LOCUS       NC_015168              19280 bp    DNA     circular CON 06-JUL-2013
DEFINITION  Bacteroides salanitronis DSM 18170 plasmid pBACSA02, complete
            sequence.
ACCESSION   NC_015168
VERSION     NC_015168.1  GI:324976987
DBLINK      Project: 63269
            BioProject: PRJNA63269
KEYWORDS    .
SOURCE      Bacteroides salanitronis DSM 18170
  ORGANISM  Bacteroides salanitronis DSM 18170
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales;
            Bacteroidaceae; Bacteroides.
REFERENCE   1  (bases 1 to 19280)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Goodwin,L., Pitluck,S.,
            Kyrpides,N., Mavromatis,K., Ivanova,N., Mikhailova,N., Teshima,H.,
            Misra,M., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D.,
            Gronow,S., Wellnitz,S., Brambilla,E., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete sequence of plasmid2 of Bacteroides salanitronis DSM
            18170
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19280)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2011) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 19280)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Goodwin,L., Pitluck,S.,
            Kyrpides,N., Mavromatis,K., Ivanova,N., Mikhailova,N., Teshima,H.,
            Misra,M., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D.,
            Gronow,S., Wellnitz,S., Brambilla,E., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (17-FEB-2011) US DOE Joint Genome Institute, 2800
            Mitchell Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to CP002532.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4087335
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
                      David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            
            ##MIGS-Data-START##
            investigation_type  :: bacteria_archaea
            project_name        :: Bacteroides salanitronis BL78, DSM 18170
            collection_date     :: isolated by  P. T. N. Lan
            lat_lon             :: Missing
            depth               :: Missing
            alt_elev            :: Missing
            country             :: Japan
            environment         :: Host
            num_replicons       :: 4
            ref_biomaterial     :: DSM 18170, CCUG 54637, JCM 13657
            biotic_relationship :: Free living
            trophic_level       :: Missing
            rel_to_oxygen       :: Anaerobe
            isol_growth_condt   :: 17158987
            sequencing_meth     :: WGS
            assembly            :: Newbler v. 2.3 (pre-release)
            finishing_strategy  :: Finished
            GOLD Stamp ID       :: Gi04003
            Type Strain         :: Yes
            Funding Program     :: DOE-GEBA 2009
            Gene Calling Method :: Prodigal 1.4, GenePRIMP
            Isolation Site      :: caecum of chicken
            Host Name           :: caecum of healthy chicken
            Cell Shape          :: Rod-shaped
            Motility            :: Nonmotile
            Sporulation         :: Nonsporulating
            Temperature Range   :: Mesophile
            Temperature Optimum :: 37CC
            Gram Staining       :: Gram-
            Diseases            :: None
            ##MIGS-Data-END##
            
            ##Genome-Assembly-Data-START##
            Finishing Goal           :: Finished
            Current Finishing Status :: Finished
            Assembly Method          :: Newbler v. 2.3
            Genome Coverage          :: 30x
            Sequencing Technology    :: 454/Illumina
            ##Genome-Assembly-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19280
                     /organism="Bacteroides salanitronis DSM 18170"
                     /mol_type="genomic DNA"
                     /strain="DSM 18170"
                     /isolation_source="cecum"
                     /host="chicken"
                     /culture_collection="DSMZ:DSM 18170"
                     /db_xref="taxon:667015"
                     /plasmid="pBACSA02"
                     /country="Japan"
                     /collected_by="P.T.N. Lan"
     gene            330..1019
                     /locus_tag="Bacsa_3705"
                     /db_xref="GeneID:10229016"
     CDS             330..1019
                     /locus_tag="Bacsa_3705"
                     /note="KEGG: bth:BT_p548204 hypothetical protein;
                     SPTR: Putative uncharacterized protein;
                     PFAM: SprT-like family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004263991.1"
                     /db_xref="GI:324976988"
                     /db_xref="GeneID:10229016"
                     /translation="MITTIQFKTLDDLFQFYNNRLFEGKLPECIVNMSRKGGSYGFFA
                     ADRWKGDSMQKKIIHEISINPDFMDRPDKEWHSTLVHEMCHLWQHDFGNPSRNCYHNK
                     QLASKMIQVGLMPTDTGEPGGKQTGQQMSHYVIEGGLFDKVFNALGADELENLRLKYR
                     PLPASFRMLPVPVPPPGKSADTEKAEDKEGDWEKSGKRKRYTCGCGNHVWGKSGLWIR
                     CEECNMLFLED"
     misc_feature    357..>761
                     /locus_tag="Bacsa_3705"
                     /note="SprT-like family; Region: SprT-like; pfam10263"
                     /db_xref="CDD:220661"
     misc_feature    363..>677
                     /locus_tag="Bacsa_3705"
                     /note="SprT homologues; Region: SprT; cl01182"
                     /db_xref="CDD:242350"
     gene            1178..1846
                     /locus_tag="Bacsa_3706"
                     /db_xref="GeneID:10228992"
     CDS             1178..1846
                     /locus_tag="Bacsa_3706"
                     /note="KEGG: bvu:BVU_1437 hypothetical protein;
                     SPTR: Putative uncharacterized protein;
                     PFAM: Abi-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004263992.1"
                     /db_xref="GI:324976989"
                     /db_xref="GeneID:10228992"
                     /translation="MKYKDYEAAFSQARLSRYLNACAGDKNKALILYRYNLKLCQKFY
                     GVLGLFEVVFRNAVNEHYKRHFGDEDWIRTQIHAGGMLESSPQVSDVTRYISKLSDAG
                     KYTHDRLVSSVSFGFWTYLFNKQPFRKGGQSLLAIFPHKTKGLGQRAIYNELMEIKSF
                     RNRIAHHEPICFDMDGNKDVEFAQSNYNQILKYVGFLGYNKNELFYGLDVLPDRTIQK
                     IRDL"
     misc_feature    1187..1690
                     /locus_tag="Bacsa_3706"
                     /note="Abi-like protein; Region: Abi_2; pfam07751"
                     /db_xref="CDD:219553"
     gene            complement(1886..2896)
                     /locus_tag="Bacsa_3707"
                     /db_xref="GeneID:10228993"
     CDS             complement(1886..2896)
                     /locus_tag="Bacsa_3707"
                     /note="InterPro IPR000525;
                     KEGG: aps:CFPG_P1-1 replication protein A;
                     PFAM: Initiator Rep protein;
                     SPTR: Initiator RepB protein;
                     PFAM: Initiator Replication protein"
                     /codon_start=1
                     /transl_table=11
                     /product="initiator RepB protein"
                     /protein_id="YP_004263993.1"
                     /db_xref="GI:324976990"
                     /db_xref="GeneID:10228993"
                     /translation="MERTKQKKNNGVVVRNKDQIQSYIMTTAKYDFNVYEKRILYRLV
                     ELAQCELQGLKFPEDCRKVEHTLWGNLIVTLPVTSILSNEDDNNYAKAKKALIALSQK
                     YFEYEDEKTWEKINIIVLPKIQKYKSTFTFQIDPRIWSCCLDFTKGFRKYELVTAMNF
                     KSVYTMRFYELMSGQKAKMSFSLNHLKEMFQVTDKYKLTADFIRKVIEPAKKELDECS
                     PYTFEWTPQKEGKKIVGFCFYPIVQPQFRDNDLYRQEIQKQTNLSWDLNRQVLGYLKL
                     SLGFSDKEIKNNRAVFIAAQFELPDIMGELAILKGKSRDKGNPKGYIINALKGKLKDK
                     QG"
     misc_feature    complement(2180..2839)
                     /locus_tag="Bacsa_3707"
                     /note="Initiator Replication protein; Region: Rep_3;
                     pfam01051"
                     /db_xref="CDD:216266"
     gene            complement(3317..4594)
                     /locus_tag="Bacsa_3708"
                     /db_xref="GeneID:10228994"
     CDS             complement(3317..4594)
                     /locus_tag="Bacsa_3708"
                     /note="InterPro IPR001668;
                     KEGG: bvu:BVU_1439 mobilization protein;
                     PFAM: Plasmid recombination enzyme;
                     SPTR: Mob421 protein"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="YP_004263994.1"
                     /db_xref="GI:324976991"
                     /db_xref="GeneID:10228994"
                     /translation="MAKTSINVRPCNIGSAERHNLRSKELDYIRPELSHRNEQWSEMR
                     IADVLEDIREKYRQHTGQSMQKKATPIREGVVVIEDGTTLRQLQDFAGRLEERFGIHT
                     FQIYTHKDEGAGVWDGNAETWKPNYHAHMIFDWTDGETGRTRKLNKQDMAEMQTILAE
                     CLGMERGISSDRKHLSAIQYKNMVEAEKAAQIEKECRKMENERNVIEEKVKQAGEKLE
                     DTQKKLKEAAAEIKVEKLKGAAADTGTALLKAGTTVIDATASLFNSGKVKRQEQEIAE
                     LKRENFELEMKSQNLQSNLRTANAQNEREREATRRAVRTGEERLKPITELFPCMENAK
                     ENIDELRTMGVGDNDIRLLLTGKEITYSGFLYDRERRKKHQVKDVKIDIAKSKSGNTT
                     IWLNDFHFKEFFKQLWIRLQKILGLGTNKGVHM"
     misc_feature    complement(4049..4561)
                     /locus_tag="Bacsa_3708"
                     /note="Plasmid recombination enzyme; Region: Mob_Pre;
                     pfam01076"
                     /db_xref="CDD:216286"
     gene            4986..5204
                     /locus_tag="Bacsa_3709"
                     /db_xref="GeneID:10228995"
     CDS             4986..5204
                     /locus_tag="Bacsa_3709"
                     /note="SPTR: Predicted protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004263995.1"
                     /db_xref="GI:324976992"
                     /db_xref="GeneID:10228995"
                     /translation="MVDKNKNLKKMKEGDLVSVSAESTGLGRPMEAVIDKIETFLGQT
                     LVTVSYTQPDENSGFGGCFVDAHITVKE"
     misc_feature    4995..>5168
                     /locus_tag="Bacsa_3709"
                     /note="lipoxygenase; Region: PLN02337"
                     /db_xref="CDD:215193"
     gene            5233..5565
                     /locus_tag="Bacsa_3710"
                     /db_xref="GeneID:10228996"
     CDS             5233..5565
                     /locus_tag="Bacsa_3710"
                     /note="KEGG: cvi:CV_2332 SOS mutagenesis;
                     SPTR: Predicted protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004263996.1"
                     /db_xref="GI:324976993"
                     /db_xref="GeneID:10228996"
                     /translation="MGNENVSKSKRGGKREGAGRKSRAGIHSVVMRVPASMEELVQAF
                     IDIYSDWIREEGDKFAPHKTNETQRALFRQTVSGMLEFERERLVKRNKEDSDRRQLRL
                     FENETKSE"
     gene            5707..6279
                     /locus_tag="Bacsa_3711"
                     /db_xref="GeneID:10228997"
     CDS             5707..6279
                     /locus_tag="Bacsa_3711"
                     /note="COGs: COG1961 Site-specific recombinase DNA
                     invertase Pin homologs;
                     InterPro IPR006119:IPR006120;
                     KEGG: mmz:MmarC7_1490 resolvase domain-containing protein;
                     PFAM: Resolvase, N-terminal; Resolvase, helix-turn-helix
                     domain;
                     SMART: Resolvase, N-terminal;
                     SPTR: Putative uncharacterized protein;
                     PFAM: Resolvase, N terminal domain; Helix-turn-helix
                     domain of resolvase"
                     /codon_start=1
                     /transl_table=11
                     /product="Resolvase domain"
                     /protein_id="YP_004263997.1"
                     /db_xref="GI:324976994"
                     /db_xref="GeneID:10228997"
                     /translation="MIIGYARVSKNDQHLDRQIDRLKKEGCERIYQEKVSGAGKIRPE
                     LDRMLDALREGDTVIVCELTRLGRSVKELFMLAERIGATGADLRSIKEPWLDTTTPQG
                     KLLFAVFSGVSQFERDIIRERTLEGLESARARGRKGGRPKADAGRIELAMKLYDSRAC
                     PVSDILKASGISKATLYAYLKDRESTEKGT"
     misc_feature    5707..6255
                     /locus_tag="Bacsa_3711"
                     /note="multiple promoter invertase; Provisional; Region:
                     mpi; PRK13413"
                     /db_xref="CDD:184041"
     misc_feature    5710..6087
                     /locus_tag="Bacsa_3711"
                     /note="Serine Recombinase (SR) family, Resolvase and
                     Invertase subfamily, catalytic domain; members contain a
                     C-terminal DNA binding domain. Serine recombinases
                     catalyze site-specific recombination of DNA molecules by a
                     concerted, four-strand cleavage and...; Region: SR_ResInv;
                     cd03768"
                     /db_xref="CDD:239737"
     misc_feature    order(5725..5727,5731..5733,5896..5901,5908..5910)
                     /locus_tag="Bacsa_3711"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239737"
     misc_feature    5731..5733
                     /locus_tag="Bacsa_3711"
                     /note="catalytic nucleophile [active]"
                     /db_xref="CDD:239737"
     misc_feature    order(5893..5895,6028..6033,6037..6042,6052..6054)
                     /locus_tag="Bacsa_3711"
                     /note="Presynaptic Site I dimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    order(5911..5913,5926..5931,6016..6018,6025..6030,
                     6037..6042,6049..6051,6058..6060)
                     /locus_tag="Bacsa_3711"
                     /note="Synaptic Antiparallel dimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    order(5980..5988,6016..6021,6028..6033,6040..6042,
                     6052..6054,6061..6063,6073..6075)
                     /locus_tag="Bacsa_3711"
                     /note="Synaptic Flat tetramer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    order(5980..5982,6031..6033,6040..6042,6052..6054,
                     6061..6063,6073..6075)
                     /locus_tag="Bacsa_3711"
                     /note="Synaptic Site I dimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    order(6055..6057,6073..6078)
                     /locus_tag="Bacsa_3711"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:239737"
     gene            complement(6319..7017)
                     /locus_tag="Bacsa_3712"
                     /db_xref="GeneID:10228998"
     CDS             complement(6319..7017)
                     /locus_tag="Bacsa_3712"
                     /note="COGs: COG0745 Response regulators consisting of a
                     CheY-like receiver domain and a winged-helix DNA-binding
                     domain;
                     InterPro IPR001789:IPR001867;
                     KEGG: pru:PRU_2320 DNA-binding response regulator;
                     PFAM: Signal transduction response regulator, receiver
                     domain; Signal transduction response regulator,
                     C-terminal;
                     SMART: Signal transduction response regulator, receiver
                     domain; Signal transduction response regulator,
                     C-terminal;
                     SPTR: Putative uncharacterized protein;
                     PFAM: Response regulator receiver domain; Transcriptional
                     regulatory protein, C terminal"
                     /codon_start=1
                     /transl_table=11
                     /product="two component transcriptional regulator, winged
                     helix family"
                     /protein_id="YP_004263998.1"
                     /db_xref="GI:324976995"
                     /db_xref="GeneID:10228998"
                     /translation="MIKLLLVEDDVNLCYIVQAGLQDVIGGYEVITAGNGLEGLHAWE
                     EHKPDIIISDIDMPEMDGFEMVRRIRETDGDTPILFASAMTSPKDVKHGYELGVNNYV
                     KKPFVPEEIDAHIHAILKMKEGARSRSVEGHCRFSHYTLDTVHATLRDDNTGKIRVLT
                     TTEAKILQLLAENKNEVIRREAILSRCWNTEDDFFASRSLDVFVTKLRKLFTDDPDVE
                     IKTARGVGLMLVAK"
     misc_feature    complement(6322..7011)
                     /locus_tag="Bacsa_3712"
                     /note="Response regulators consisting of a CheY-like
                     receiver domain and a winged-helix DNA-binding domain
                     [Signal transduction mechanisms / Transcription]; Region:
                     OmpR; COG0745"
                     /db_xref="CDD:223816"
     misc_feature    complement(6661..7005)
                     /locus_tag="Bacsa_3712"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(6703..6708,6715..6717,6772..6774,
                     6832..6834,6856..6858,6991..6996))
                     /locus_tag="Bacsa_3712"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(6856..6858)
                     /locus_tag="Bacsa_3712"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(6832..6840,6844..6849))
                     /locus_tag="Bacsa_3712"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(6700..6708)
                     /locus_tag="Bacsa_3712"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(6331..6615)
                     /locus_tag="Bacsa_3712"
                     /note="Effector domain of response regulator. Bacteria and
                     certain eukaryotes like protozoa and higher plants use
                     two-component signal transduction systems to detect and
                     respond to changes in the environment. The system consists
                     of a sensor histidine kinase and...; Region: trans_reg_C;
                     cd00383"
                     /db_xref="CDD:238225"
     misc_feature    complement(order(6340..6342,6355..6357,6385..6390,
                     6412..6414,6421..6423,6478..6483,6538..6540))
                     /locus_tag="Bacsa_3712"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238225"
     gene            complement(7014..8321)
                     /locus_tag="Bacsa_3713"
                     /db_xref="GeneID:10228999"
     CDS             complement(7014..8321)
                     /locus_tag="Bacsa_3713"
                     /note="COGs: COG2205 Osmosensitive K+ channel histidine
                     kinase;
                     InterPro IPR003661:IPR003594;
                     KEGG: bvu:BVU_0833 two-component system sensor histidine
                     kinase;
                     PFAM: ATPase-like, ATP-binding domain; Signal transduction
                     histidine kinase, subgroup 1, dimerisation/phosphoacceptor
                     domain;
                     SMART: ATPase-like, ATP-binding domain; Signal
                     transduction histidine kinase, subgroup 1,
                     dimerisation/phosphoacceptor domain;
                     SPTR: Two-component system sensor histidine kinase;
                     PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like
                     ATPase; His Kinase A (phosphoacceptor) domain"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane sensor signal transduction
                     histidine kinase"
                     /protein_id="YP_004263999.1"
                     /db_xref="GI:324976996"
                     /db_xref="GeneID:10228999"
                     /translation="MRYNNFILCFTLLGIISILSLQYVWLNNTYILIKNNIFIECNNI
                     IEEALKKETSIIAKQLPEGTRIIGGANTDSIPQSTYLYEGISKLGYKLSLQRIDSITN
                     LLLKEKNINNRFYIRIINPKNEEIYASYNKCNQKNALTTIESKVIPIKVDLSKGIQLV
                     LENPQISIFERMNILLISTIIIMIFVIGCIIYQVKIVSKQKKIFQIREDFSYAMVHDM
                     KTPLTTIFTALSFLHSGRLDDKPETKEKFFNVAKEEADRLLTLTNKLLTISKLENKKM
                     KMECEKIALEPMLVRLADKFKVKSHKPVSFEFDLQTPEIYADAEYIEEVFSNLIDNSI
                     KYSKERVDIRVSSSKNDLYSIIKIYDNGLGISEKDQRSIFNKYERAAAGSRSNKKKAS
                     GFGLGLNFVQQVIEAHKGKIFVNSIEGEFTEFIIYLPLMVKEL"
     sig_peptide     complement(8244..8321)
                     /locus_tag="Bacsa_3713"
                     /note="Signal predicted by SignalP 3.0 HMM"
     misc_feature    complement(7020..>7709)
                     /locus_tag="Bacsa_3713"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: BaeS; COG0642"
                     /db_xref="CDD:223715"
     misc_feature    complement(7512..7709)
                     /locus_tag="Bacsa_3713"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    complement(order(7527..7529,7539..7541,7548..7550,
                     7560..7562,7569..7571,7581..7583,7638..7640,7647..7649,
                     7659..7661,7668..7670,7680..7682,7692..7694))
                     /locus_tag="Bacsa_3713"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    complement(7674..7676)
                     /locus_tag="Bacsa_3713"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    complement(7038..7358)
                     /locus_tag="Bacsa_3713"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(7050..7052,7056..7061,7074..7076,
                     7080..7082,7128..7139,7227..7232,7236..7238,7242..7244,
                     7248..7250,7317..7319,7326..7328,7338..7340))
                     /locus_tag="Bacsa_3713"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(7326..7328)
                     /locus_tag="Bacsa_3713"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(7131..7133,7137..7139,7230..7232,
                     7236..7238))
                     /locus_tag="Bacsa_3713"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            8431..8547
                     /locus_tag="Bacsa_3714"
                     /db_xref="GeneID:10229000"
     CDS             8431..8547
                     /locus_tag="Bacsa_3714"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004264000.1"
                     /db_xref="GI:324976997"
                     /db_xref="GeneID:10229000"
                     /translation="MKQIQDLEKNEMIEIFGGEWMVLNGEWVYVDVTRGKDD"
     gene            8674..8829
                     /locus_tag="Bacsa_3715"
                     /db_xref="GeneID:10229001"
     CDS             8674..8829
                     /locus_tag="Bacsa_3715"
                     /note="InterPro IPR010133;
                     TIGRFAM: Bacteriocin-type signal sequence motif;
                     TIGRFAM: bacteriocin-type signal sequence"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-type signal sequence"
                     /protein_id="YP_004264001.1"
                     /db_xref="GI:324976998"
                     /db_xref="GeneID:10229001"
                     /translation="MKKNELKTLEIEELKNVNGGVAPGPNGESCTEHGLPDFLKNTIL
                     LDILKHR"
     gene            8892..9005
                     /locus_tag="Bacsa_3716"
                     /db_xref="GeneID:10229002"
     CDS             8892..9005
                     /locus_tag="Bacsa_3716"
                     /note="SPTR: Predicted protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004264002.1"
                     /db_xref="GI:324976999"
                     /db_xref="GeneID:10229002"
                     /translation="MKELNKDEDLSITGGYFPPTEEQLEKLNPIERIIICW"
     gene            9022..9174
                     /locus_tag="Bacsa_3717"
                     /db_xref="GeneID:10229003"
     CDS             9022..9174
                     /locus_tag="Bacsa_3717"
                     /note="SPTR: Putative uncharacterized protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004264003.1"
                     /db_xref="GI:324977000"
                     /db_xref="GeneID:10229003"
                     /translation="MEKNEMMRTMSLQEQQEINGGGALDILINLKSATPFPKCYLHKE
                     KWTFDS"
     gene            complement(9279..10566)
                     /locus_tag="Bacsa_3718"
                     /pseudo
                     /db_xref="GeneID:10229004"
     gene            10857..11012
                     /locus_tag="Bacsa_3719"
                     /db_xref="GeneID:10229005"
     CDS             10857..11012
                     /locus_tag="Bacsa_3719"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004264004.1"
                     /db_xref="GI:324977001"
                     /db_xref="GeneID:10229005"
                     /translation="MKENVFMVELNQKEMSEVNGGGIWTEVFKALIASYEMASDFKEG
                     WDSVPDL"
     gene            11062..11196
                     /locus_tag="Bacsa_3720"
                     /db_xref="GeneID:10229006"
     CDS             11062..11196
                     /locus_tag="Bacsa_3720"
                     /note="SPTR: TldD/PmbA family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004264005.1"
                     /db_xref="GI:324977002"
                     /db_xref="GeneID:10229006"
                     /translation="MMKNESYVELSKKENSEIYGGKSFMTTIGELCHKGWNEVKSWFR
                     "
     gene            11270..12133
                     /locus_tag="Bacsa_3721"
                     /db_xref="GeneID:10229007"
     CDS             11270..12133
                     /locus_tag="Bacsa_3721"
                     /note="InterPro IPR003675;
                     KEGG: bfs:BF1825 putative transmembrane protease;
                     PFAM: Abortive infection protein;
                     SPTR: Putative transmembrane protease;
                     PFAM: CAAX amino terminal protease family"
                     /codon_start=1
                     /transl_table=11
                     /product="Abortive infection protein"
                     /protein_id="YP_004264006.1"
                     /db_xref="GI:324977003"
                     /db_xref="GeneID:10229007"
                     /translation="MCYIVKKNRVPLWADLLIFLVFLFIASLIGVESTLSLIGSTEFE
                     SVKYFFLSTIISSIIVLLAILLQHYVIDKRPLSELGLCTTHFVWKHSSMVVVWTFIVF
                     VIGFLICLLSGDVSIVSVYWNLKDLSLSLLMFTFGAFYEEIIMRGYLLTRLCRSGLNV
                     WLCLIITAIVFSAMHLANPNVNVCSVVNLFLFGILDGCIFLYTKSLWVSVIAHCAWNW
                     IQGSILGFKVSGCEFFQPIINLDMPSYNLVNGGLFGFEGSIICTILLIPFIIIFINLL
                     SKSIAKDEFQH"
     misc_feature    11648..11926
                     /locus_tag="Bacsa_3721"
                     /note="CAAX protease self-immunity; Region: Abi;
                     pfam02517"
                     /db_xref="CDD:217080"
     gene            12234..13403
                     /locus_tag="Bacsa_3722"
                     /db_xref="GeneID:10229008"
     CDS             12234..13403
                     /locus_tag="Bacsa_3722"
                     /note="COGs: COG1566 Multidrug resistance efflux pump;
                     InterPro IPR006143;
                     KEGG: dfe:Dfer_4909 secretion protein HlyD family protein;
                     PFAM: Secretion protein HlyD;
                     SPTR: Secretion protein HlyD family protein;
                     PFAM: HlyD family secretion protein"
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD family protein"
                     /protein_id="YP_004264007.1"
                     /db_xref="GI:324977004"
                     /db_xref="GeneID:10229008"
                     /translation="MLLPNEWIENSIETYIYQHTTKSQVIYWVVLLAVTVTLVALPFV
                     YVDISVQGSGVVRPVAEKAEITSSITEIVDSVFVKEGDQVNKGDVILRFRTNNSDYKI
                     NYQTSRLNDCSAQLADLAFLAKGERPERFSSPVRQQEYAYFIRKKQELETALAQAEKE
                     YTRNRTLFEKKVISEEEYDSYYFKLKSQQNELASLVQSQLSTWQADQNTYRNTYNEMN
                     SSLNQEIKDKDMYIVRSPVDGTVDQFSGVYRGSSIQAGQSLAVISPDSTLCLEVYVTP
                     RNIGFMSVGMPVNVQVESFNYNEWGTIPGRVKDISSDFLTDSQGNSFYKVKCEMERDY
                     LQLKNGRVGKLKKGMTVNAHFMVTRRSLFDLLYQKMDGWVNPKQYENETMVAKLN"
     misc_feature    12369..13331
                     /locus_tag="Bacsa_3722"
                     /note="type I secretion membrane fusion protein, HlyD
                     family; Region: type_I_hlyD; TIGR01843"
                     /db_xref="CDD:130902"
     misc_feature    12414..12542
                     /locus_tag="Bacsa_3722"
                     /note="Biotin-lipoyl like; Region: Biotin_lipoyl_2;
                     pfam13533"
                     /db_xref="CDD:205711"
     misc_feature    12927..13253
                     /locus_tag="Bacsa_3722"
                     /note="HlyD family secretion protein; Region: HlyD_3;
                     pfam13437"
                     /db_xref="CDD:222128"
     gene            13432..15597
                     /locus_tag="Bacsa_3723"
                     /db_xref="GeneID:10229009"
     CDS             13432..15597
                     /locus_tag="Bacsa_3723"
                     /EC_number="3.6.3.44"
                     /note="COGs: COG2274 ABC-type bacteriocin/lantibiotic
                     exporter contain an N-terminal double-glycine peptidase
                     domain;
                     InterPro
                     IPR003593:IPR005074:IPR001140:IPR003439:IPR005897;
                     KEGG: zpr:ZPR_4399 probable bacteriocin/lantibiotic ABC
                     transporter, ATP-binding protein;
                     PFAM: ABC transporter-like; Peptidase C39, bacteriocin
                     processing; ABC transporter, transmembrane domain;
                     PRIAM: Xenobiotic-transporting ATPase;
                     SMART: ATPase, AAA+ type, core;
                     SPTR: Bacteriocin/lantibiotic ABC transporter;
                     TIGRFAM: Peptidase C39, ABC-type bacteriocin transporter;
                     PFAM: ABC transporter transmembrane region; ABC
                     transporter; Peptidase C39 family;
                     TIGRFAM: ABC-type bacteriocin transporter; type I
                     secretion system ABC transporter, HlyB family"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-type bacteriocin transporter"
                     /protein_id="YP_004264008.1"
                     /db_xref="GI:324977005"
                     /db_xref="GeneID:10229009"
                     /translation="MYKKGIKIKQHDITDCGAACLASVCAHYGLQFPVARIRQYAFTD
                     QKGTNVLGLIEAANRLGLSAKGVRAQFEALAIVPKPTIAHVIVHEHLQHFVVIYKVEK
                     GHITYMDPGDGRMHKVTDEEFKRMWTGVLVLMEPEETFKKGNMKTSMTRKFFSLLAPH
                     KSVMMQAVFGALVYSILGLSTSVYVGKITDYVLVDGNINLLNLMGVVMIVILILRTFI
                     GAMKSILALKTGQRIDAALILGYYKHLLTLPQQFFDTMRVGEIISRVNDAVKIRNFIN
                     NVSLDLVVNMMILLFSVGLMFVYSWELALVTLASAPLFLLIFWGFNRLNRKYQRGIME
                     SSADLEAQLVESINSISTIKRFGIEDFANLKTETRFVHLLKNTFRSIYGAIMAQGGIQ
                     FVSTAITIAVLWMGSVLVIDKELTPGTLMVFYSLISYVISPIGSLISSNQTIQDALIA
                     ADRLFQIMDLEREQDDSQKIELEPDMIGDITFENVSFRYGSRKEVFKGLNLKIEKGKT
                     TAVIGESGSGKTTLISLLQHIYPIQSGQIRIGEYDIAQISNRSLRRRVGTVPQQIELF
                     AGTIIENIAVGDLQPDMKRIVDLVEQLGLKDFIERLPNGYMTYIGEHGASLSGGERQR
                     IAIARALYKEPEILIFDEATSSLDSISEKHVKQTLDALAKRGKTVIVIAHRLSTVKNA
                     DRIVVLDKGQVAETGTHKELFNSGGIYSRLWNEQFDQLD"
     misc_feature    13453..15579
                     /locus_tag="Bacsa_3723"
                     /note="ABC-type bacteriocin/lantibiotic exporters, contain
                     an N-terminal double-glycine peptidase domain [Defense
                     mechanisms]; Region: SunT; COG2274"
                     /db_xref="CDD:225183"
     misc_feature    13453..13848
                     /locus_tag="Bacsa_3723"
                     /note="A sub-family of peptidase family C39. Peptidase
                     family C39 mostly contains bacteriocin-processing
                     endopeptidases from bacteria. The cysteine peptidases in
                     family C39 cleave the &quot;double-glycine&quot; leader
                     peptides from the precursors of various...; Region:
                     Peptidase_C39B; cd02418"
                     /db_xref="CDD:239099"
     misc_feature    order(13459..13461,13477..13479,13708..13710,13756..13758)
                     /locus_tag="Bacsa_3723"
                     /note="putative active site [active]"
                     /db_xref="CDD:239099"
     misc_feature    13918..14733
                     /locus_tag="Bacsa_3723"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:216049"
     misc_feature    14869..15579
                     /locus_tag="Bacsa_3723"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    14968..14991
                     /locus_tag="Bacsa_3723"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(14977..14982,14986..14994,15112..15114,15352..15357,
                     15451..15453)
                     /locus_tag="Bacsa_3723"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    15103..15114
                     /locus_tag="Bacsa_3723"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    15280..15309
                     /locus_tag="Bacsa_3723"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    15340..15357
                     /locus_tag="Bacsa_3723"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    15364..15375
                     /locus_tag="Bacsa_3723"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    15439..15459
                     /locus_tag="Bacsa_3723"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            15738..17063
                     /locus_tag="Bacsa_3724"
                     /db_xref="GeneID:10229010"
     CDS             15738..17063
                     /locus_tag="Bacsa_3724"
                     /note="COGs: COG1538 Outer membrane protein;
                     InterPro IPR003423;
                     KEGG: pdi:BDI_3572 putative outer membrane
                     transport/efflux protein;
                     PFAM: Outer membrane efflux protein;
                     SPTR: Putative uncharacterized protein;
                     PFAM: Outer membrane efflux protein"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane efflux protein"
                     /protein_id="YP_004264009.1"
                     /db_xref="GI:324977006"
                     /db_xref="GeneID:10229010"
                     /translation="MKGLVSILAFAGLLACQGNVQAQVKKWTLAECIDYAVTHNIEVK
                     QSDNQIQNLKVQRNTLRNSFLPDLNAGASQNFTFGRSLNQNNTYEDSNIQNSSFSVTT
                     EIPIFAGFKRTASIAQNRFDLLAAEANRELIENNLSLNVAGAYFQILLNKEIYRIALE
                     QIQLTKEQETCTQLLIENGKAAESQLYDVRAQLADDELTATEARNSLRLAYLDLAQLM
                     ELKGHEQFDIDSLGGEIAIADTLSPVSIYQSALTCMPQIRQAYYTLQSKTKGIRIAKS
                     GYYPTLSFAAGINTNYYDNGSGLGETFQRQLNNNMQKSLCFTISIPLFDRFSTRNQVR
                     AARIDEDNARLSLENEKKQLYKDIEQAYMDAISAFEKYRSTTKAVIANQEAHRYALEK
                     YAAGKSTVFEYNEIKMKLADALSQQSQAKYTYLLKDRILAFYSCFSLTD"
     sig_peptide     15738..15803
                     /locus_tag="Bacsa_3724"
                     /note="Signal predicted by SignalP 3.0 HMM"
     misc_feature    15759..17015
                     /locus_tag="Bacsa_3724"
                     /note="Outer membrane protein [Cell envelope biogenesis,
                     outer membrane / Intracellular trafficking and secretion];
                     Region: TolC; COG1538"
                     /db_xref="CDD:224455"
     gene            17077..17286
                     /locus_tag="Bacsa_3725"
                     /db_xref="GeneID:10229011"
     CDS             17077..17286
                     /locus_tag="Bacsa_3725"
                     /note="COGs: COG3655 transcriptional regulator protein;
                     InterPro IPR001387;
                     KEGG: bcb:BCB4264_A2209 transcription regulator, Cro/CI
                     family -related protein;
                     PFAM: Helix-turn-helix type 3;
                     SMART: Helix-turn-helix type 3;
                     SPTR: XRE family transcriptional regulator;
                     PFAM: Helix-turn-helix"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator, XRE family"
                     /protein_id="YP_004264010.1"
                     /db_xref="GI:324977007"
                     /db_xref="GeneID:10229011"
                     /translation="MHSIKINLDVVLNKRGMTLNELSEKTGVSIANLSNLKNNRVVSV
                     RFSTLGRICKALECQPADILKYEDD"
     misc_feature    17110..17265
                     /locus_tag="Bacsa_3725"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; Region: HTH_XRE; cd00093"
                     /db_xref="CDD:238045"
     misc_feature    order(17110..17112,17185..17187)
                     /locus_tag="Bacsa_3725"
                     /note="salt bridge; other site"
                     /db_xref="CDD:238045"
     misc_feature    order(17113..17115,17188..17190)
                     /locus_tag="Bacsa_3725"
                     /note="non-specific DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238045"
     misc_feature    order(17131..17136,17167..17169,17176..17178,17188..17193)
                     /locus_tag="Bacsa_3725"
                     /note="sequence-specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238045"
     gene            17386..17877
                     /locus_tag="Bacsa_3726"
                     /db_xref="GeneID:10229012"
     CDS             17386..17877
                     /locus_tag="Bacsa_3726"
                     /note="KEGG: bth:BT_3259 hypothetical protein;
                     SPTR: Putative uncharacterized protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004264011.1"
                     /db_xref="GI:324977008"
                     /db_xref="GeneID:10229012"
                     /translation="MEIITATTIFLASLNVYGECGFAYNAETSEDGIVTAKAVYHKSV
                     CGKYLSPTLKYNYVYDGEQRLAQKEVLKWNCVTEKWDKSHILNYMYDENGYTIEYAVW
                     DSGKQEYADVVAKQTYHESIDGALYIALYRWDDSGNDWVKQNDMVAMNLSGELLTSFE
                     FEL"
     misc_feature    17395..17739
                     /locus_tag="Bacsa_3726"
                     /note="Family of unknown function (DUF3836); Region:
                     DUF3836; pfam12930"
                     /db_xref="CDD:221862"
     gene            17908..18048
                     /locus_tag="Bacsa_3727"
                     /db_xref="GeneID:10229013"
     CDS             17908..18048
                     /locus_tag="Bacsa_3727"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004264012.1"
                     /db_xref="GI:324977009"
                     /db_xref="GeneID:10229013"
                     /translation="MEKKNLERKVRLIAIEEMRNVNGGANIVAGDEFSQLKLPIGMRK
                     KF"
     gene            complement(18166..18429)
                     /locus_tag="Bacsa_3728"
                     /db_xref="GeneID:10229014"
     CDS             complement(18166..18429)
                     /locus_tag="Bacsa_3728"
                     /note="KEGG: bfr:BF2825 hypothetical protein;
                     SPTR: Putative uncharacterized protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004264013.1"
                     /db_xref="GI:324977010"
                     /db_xref="GeneID:10229014"
                     /translation="MENKRNNLRENMKAGLSSLVRPTTVAVKQSDLRTQEKPKYKTCN
                     YITDPSRHNRLKRYATDNGMTLLQAFNEAIDLYLSDKGERYAP"
     gene            complement(18439..19200)
                     /locus_tag="Bacsa_3729"
                     /db_xref="GeneID:10229015"
     CDS             complement(18439..19200)
                     /locus_tag="Bacsa_3729"
                     /note="COGs: COG1192 ATPase involved in chromosome
                     partitioning;
                     InterPro IPR002586;
                     KEGG: bth:BT_p548231 chromosome-partitioning ATPase;
                     PFAM: Cobyrinic acid a,c-diamide synthase;
                     SPTR: Putative uncharacterized protein;
                     PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain"
                     /codon_start=1
                     /transl_table=11
                     /product="Cobyrinic acid ac-diamide synthase"
                     /protein_id="YP_004264014.1"
                     /db_xref="GI:324977011"
                     /db_xref="GeneID:10229015"
                     /translation="MAKIVSIINHKGGVGKTATAANLGAALQIRGKRVLLIDMDAQSN
                     LTDCLGVSTELDDTIYQAMRGYIPLPIVKNEDGLDIVPSCLDMSAIEMEIMQKYAREQ
                     ILHKLISQVQEQYDYILIDCPPSLSILTINAMTASDCIIIPVEAEYLAMRGMGRLTNV
                     IHEVKNNLNPKLRISGILITKYDRRKNFNQDIQEIIRDTFQGDVFTTTIRTNVAIGEA
                     TAAKHDIFHYAPKSSGAEDYASFCDEFLKKESTFN"
     misc_feature    complement(18457..19200)
                     /locus_tag="Bacsa_3729"
                     /note="ATPases involved in chromosome partitioning [Cell
                     division and chromosome partitioning]; Region: Soj;
                     COG1192"
                     /db_xref="CDD:224113"
     misc_feature    complement(<19075..19191)
                     /locus_tag="Bacsa_3729"
                     /note="ParA and ParB of Caulobacter crescentus belong to a
                     conserved family of bacterial proteins implicated in
                     chromosome segregation. ParB binds to DNA sequences
                     adjacent to the origin of replication and localizes to
                     opposite cell poles shortly following the...; Region:
                     ParA; cd02042"
                     /db_xref="CDD:238997"
     misc_feature    complement(19150..19170)
                     /locus_tag="Bacsa_3729"
                     /note="P-loop; other site"
                     /db_xref="CDD:238997"
     misc_feature    complement(19150..19152)
                     /locus_tag="Bacsa_3729"
                     /note="Magnesium ion binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238997"
     misc_feature    complement(18661..>18861)
                     /locus_tag="Bacsa_3729"
                     /note="ParA and ParB of Caulobacter crescentus belong to a
                     conserved family of bacterial proteins implicated in
                     chromosome segregation. ParB binds to DNA sequences
                     adjacent to the origin of replication and localizes to
                     opposite cell poles shortly following the...; Region:
                     ParA; cd02042"
                     /db_xref="CDD:238997"
     misc_feature    complement(18838..18840)
                     /locus_tag="Bacsa_3729"
                     /note="Magnesium ion binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238997"
ORIGIN      
        1 ataaatcaaa tgaatcaacg attttatttt tcccgtttat tcactcccgt tttctctatt
       61 gcattttaag atggaatagg acatatcctt attggactat ttttagaata agaatttaat
      121 atttatgcat tatgtgtgtt atttccacta atccactaaa atactaatat ttgtaatgta
      181 cattatattt tatataaata tttgataaac aatgaaatat aaaatatgta tatacactaa
      241 ttcactaata aactaaacaa ctaataacct attttttttg taatgtacat taaaaataat
      301 atttttgcaa gaaaataaac atcagaaaaa tgataacaac gatacagttt aagacgcttg
      361 acgatttgtt tcagttttat aataaccgcc tgttcgaagg gaaactgcca gaatgcattg
      421 tgaatatgag ccggaaggga ggttcttatg gttttttcgc tgcagaccga tggaaagggg
      481 attcaatgca aaagaaaatc atccatgaaa tcagtatcaa tcctgatttt atggatcgac
      541 cggataaaga atggcattcg actttagtac acgaaatgtg ccatctttgg cagcatgatt
      601 ttgggaatcc aagccggaac tgttatcata acaagcaatt ggcgtctaaa atgatacagg
      661 tcggtctgat gccgacagac acgggggaac cgggagggaa acaaacaggg caacagatgt
      721 cccattatgt aattgaaggc ggcttgtttg ataaggtttt caatgcgctt ggggctgatg
      781 aattggagaa cctacgtttg aaatacagac ctttgcctgc ttctttccgg atgcttccag
      841 tgcctgtacc tccaccggga aaatctgcag atacagaaaa agctgaagat aaggaggggg
      901 attgggagaa aagcgggaaa cgcaagagat acacttgcgg atgtggaaac catgtatggg
      961 gaaaatctgg tttgtggatt aggtgcgaag agtgtaatat gctgtttttg gaggattaaa
     1021 tgaaactgga ttgtcggcga atcgaagccg gttctttatt ctgtataatg gcataaaaaa
     1081 caaaaccctg aagtttgtct ttcgacaggg acgacagggg attactttgc aaaagtacgc
     1141 atttgtattt atatttgcaa ataaaacgat agaaatcatg aaatataaag attatgaagc
     1201 ggctttctcc caagcccgtt taagcagata cctaaatgct tgtgctggag acaagaataa
     1261 ggcactcata ctatacaggt acaatttgaa attgtgtcag aaattttatg gcgtacttgg
     1321 attgtttgaa gtcgtttttc gcaatgcggt aaatgaacac tataagcgtc atttcggtga
     1381 tgaagattgg attcggacgc agattcatgc aggaggaatg ttagagagca gtccacaggt
     1441 atcagatgta acccgttaca tctcaaaact atcggatgcg gggaagtaca cgcatgacag
     1501 gttggtatct tcggtaagct tcggcttctg gacctatctt ttcaacaaac agccatttcg
     1561 gaaaggcggt cagagtctat tggctatctt tccgcacaag accaaagggt tggggcaaag
     1621 ggcaatttac aacgagttga tggaaatcaa aagtttcagg aaccgaattg cccaccatga
     1681 acccatatgt tttgacatgg acggaaacaa ggacgtggaa tttgcacaat ccaattacaa
     1741 ccaaatcctg aagtatgttg gttttttggg gtacaacaag aatgaattgt tctatgggtt
     1801 ggatgtgctg cctgacagga caatccaaaa aataagagac ctataacaat tgaagccggg
     1861 attatccgtt tcaaatatcc cggcttcatc cttgtttgtc cttcagtttt cctttaagtg
     1921 cattgatgat ataccctttg gggtttccct tgtctctcga ttttcctttt agtatagcca
     1981 gttcacccat aatgtccggc agttcgaact gtgcggcaat gaaaacagcc cggttgttct
     2041 tgatttcctt gtctgaaaat ccaagcgaga gcttcaagta gccaagcact tgcctgttca
     2101 gatcccacga aaggtttgtc tgcttctgga tttcctgccg gtagaggtca ttatccctga
     2161 actgcggctg tactatcgga taaaaacaga acccgacaat tttctttcct tctttctgag
     2221 gggtccactc gaaagtatag ggggagcact cgtccagctc tttttttgcc ggctcaatga
     2281 ctttccgtat gaaatctgcc gtcagtttgt atttgtcggt tacctggaac atttccttga
     2341 gatggttaag tgagaatgac attttcgctt tctgaccgct catcagttca tagaagcgca
     2401 ttgtatagac gcttttgaag ttcatggctg tcactaactc gtatttgcgg aatcctttag
     2461 tgaagtcaag gcagcagctc caaatccttg ggtctatttg aaacgtgaac gtgctcttgt
     2521 atttttgaat ttttggcaaa acaatgatat ttatcttttc ccatgttttt tcatcttcat
     2581 attcaaaata tttctgagac aaggctatca aggctttttt tgctttcgca tagttattgt
     2641 catcttcatt ggatagtatc gatgtgaccg ggagggtcac tattaagttt ccccaaagcg
     2701 tgtgttccac ttttctacaa tcttccggga atttcaaccc ctgcaattca cattgggcaa
     2761 gttctacaag cctgtataga attctttttt cgtacacatt gaaatcatat tttgccgtag
     2821 tcatgatgta gctttgtatc tggtctttgt ttctgactac tactccgttg ttttttttct
     2881 gtttcgtgcg ttccataatc caattggctt tatgttgttt tgcaaagata gctattatta
     2941 tgacttgtac aaatgaaagt catcgataat ataaaaatcc attccaaaag tcatagtttg
     3001 aggcaaaaaa tccattccaa aagtcatagt ttgtattcca aaagtcataa taagatgtta
     3061 aattctttct gtaattaatt gataatcagc tgaaatttag ttaaaacaaa aaagtcgata
     3121 agtatataca agttatgcat ataaacaagt caaagaattt tttagcggaa tgtcacgaaa
     3181 tccattccaa aagtcataat tccgttgaaa aggaaaagca aattgtcagc atagcaggaa
     3241 tagggacgga tttttctgcg tgttaaatta tgtatattta tgtaattata tatttaattc
     3301 atgttgaaaa acataattac atatggacac ccttgtttgt gcctaatccg agtatcttct
     3361 gtagtcttat ccatagctgt ttgaaaaatt ccttgaagtg aaaatcgttc agccaaatgg
     3421 tcgtgttgcc agacttgctt ttggctatgt ctattttcac gtccttgacc tgatgctttt
     3481 ttctgcgttc ccgatcgtac aggaatcctg aataggttat ttcttttcct gtaagcagga
     3541 gccggatatc gttatcaccg acccccattg tccggagttc atcgatgttc tctttggcgt
     3601 tttccatgca ggggaacaac tcggttatcg gcttcagcct ttcctctccg gttctgacag
     3661 ccctgcgtgt ggcttcccgt tccctttcgt tttgggcgtt tgctgtacgc aggttgctct
     3721 ggaggttctg gcttttcatc tccagttcaa aattctccct tttcagttct gctatctcct
     3781 gctcctgccg tttgaccttt ccggagttga aaaggctggc tgtagcatcg atgacggtag
     3841 ttccggcttt cagcaaggct gtccccgtgt cggctgccgc ccctttcagc ttttccacct
     3901 ttatttcagc ggctgcttct ttgagcttct tttgggtgtc ctccagcttt tcccctgcct
     3961 gtttcacttt ttcctctatg acgttgcgct cattctccat cttacggcat tctttttcga
     4021 tttgcgccgc tttctccgct tcgaccatat tcttgtactg gatggcggaa aggtgcttac
     4081 ggtcggaaga aatgcccctt tccatgccaa ggcattccgc cagtatggtc tgcatttccg
     4141 ccatgtcctg cttgttcagc ttccgggttc tccctgtttc cccgtccgtc cagtcgaaaa
     4201 tcatgtgcgc atggtagttc ggcttccatg tttccgcgtt cccgtcccaa acgccggctc
     4261 cttcgtcctt gtgcgtgtag atttggaacg tgtgtattcc gaaacgttcc tccaacctcc
     4321 cggcaaagtc ctgtagctgc cggagtgtcg tgccgtcctc gatcacgacc actccctcgc
     4381 ggatgggtgt cgccttcttc tgcatggact gcccggtgtg ctgcctgtac ttttccctta
     4441 tgtcctccag cacgtccgca atcctcattt ccgaccattg ctcgttgcgg tgggagagtt
     4501 ccgggcgtat gtagtcgagt tccttgctgc ggaggttgtg ccgttccgcg ctgccgatgt
     4561 tgcagggtct tacgttgatg cttgtctttg ccataacctt tctcttttcg ttggtggata
     4621 tccgtttgca tcgccatcga gcttgccgat ggcggacggg gtcgaggggt gtcccctcgc
     4681 acacgaccct ttagggtcat agtgtgctat aacctcgcaa gcaaagttaa gccattcgga
     4741 cggaatttgc aaatgccaag tgtggaaaga gcacataggt cggtacacaa agtacactca
     4801 gaaaaatcat cggtcgggga acgcctgcac ggcaaggggg tgcacccgca ctcccgacga
     4861 gtgcatccat tagaagccat ttttccgaaa gtaatttcat tgtatcaaat tcatgtagat
     4921 taactattga aattgttaca taatcaatat ttattgtact tttgcgatga aaaaaggtgt
     4981 catttatggt ggataagaat aaaaatttaa agaagatgaa agaaggagat ttggtatcgg
     5041 tgtccgctga atccacaggc ttaggcagac caatggaggc tgttatagac aagattgaaa
     5101 cattccttgg tcaaaccctt gtcacggtca gttatacgca acctgacgaa aattccggat
     5161 tcggtggttg ctttgttgat gcacatatca ctgtgaagga ataaaaacag ataaatttga
     5221 taaattggaa gtatgggaaa tgaaaatgta tcaaaatcaa agagaggcgg aaaacgggag
     5281 ggagcaggta ggaaaagccg tgccggcatc cattcggtag tcatgcgtgt acctgcatca
     5341 atggaggaac ttgtacaggc attcattgat atttattcgg actggattcg tgaagaagga
     5401 gacaaattcg ctccacacaa aaccaatgaa acgcaaaggg ctttgttcag gcagacggtt
     5461 tcagggatgt tggaatttga acgtgaacgg ttggtgaaaa gaaacaagga ggatagcgac
     5521 aggcgtcaac tccgcttgtt tgaaaacgaa acgaaatcag aatagcgaat tttaaaaaac
     5581 gaaggttttt catacacgtt ccggtctttc caagttgtgt aggaaatgct gttcctgttt
     5641 gtctgaaaac cggtcttttt atcaaagtat gaaaaatagt atgtatgaca tattacagac
     5701 aagaccatga ttataggata tgcaagggtt tcgaagaatg accagcacct tgaccggcag
     5761 atagaccggt tgaaaaaaga gggatgcgag cggatttatc aggaaaaagt gtctggcgca
     5821 ggaaaaataa gacctgaact ggataggatg ctggatgcgc ttcgtgaagg agatacagtc
     5881 atcgtatgcg agctgactag gttggggcgt tccgtaaagg agctttttat gctggctgaa
     5941 cgtattggcg caacgggtgc ggatctgcgt tcgattaaag agccttggct tgacacgacc
     6001 actccgcaag gtaaactgct ttttgccgta ttctcaggcg tgagccagtt tgagcgtgac
     6061 attatccggg aaagaaccct tgaagggctg gaatccgcac gggcaagggg acgcaagggt
     6121 gggagaccga aagccgatgc ggggcgcata gaacttgcca tgaagcttta tgattcccgt
     6181 gcgtgtcccg tgtctgacat tctcaaggct tcaggcataa gcaaagccac cctgtacgcc
     6241 tatttaaagg acagggaaag tacggaaaag ggaacctgaa tggaatcctt ttccgtaagg
     6301 ttatgtaatt ccgatacgtt actttgccac cagcatcagt ccgacacctc tcgcggtctt
     6361 aatctccaca tccggatcat cggtaaagag cttgcggagt ttggtgacaa atacatcgag
     6421 gctacgggac gcgaaaaaat cgtcttccgt attccagcat cggctcagga tggcttcgcg
     6481 gcggatgacc tcattcttgt tttcggcgag aagctgcagg attttggctt ccgttgtggt
     6541 caatacacgg attttacccg tgttgtcatc acgcagggtg gcatgtacgg tgtcaagcgt
     6601 gtaatggctg aacctgcagt gcccctctac cgacctgctt ctggcacctt ccttcatttt
     6661 caggatggcg tggatgtgtg cgtctatctc ttccgggaca aacggcttct ttacgtagtt
     6721 gttcacgccc agttcgtagc cgtgtttcac gtctttgggc gatgtcatgg cggaagcgaa
     6781 caggattggc gtgtctccgt ccgtctcacg gatgcgcctt accatctcga acccgtccat
     6841 ttcgggcatg tcgatgtcgg atatgatgat gtcaggtttg tgttcctccc aagcgtgcag
     6901 accttccagt ccgtttccgg cggtaatcac ttcatagccg ccgattacat cctgcagacc
     6961 tgcctgtacg atgtagcata agttcacatc gtcttcaacg agtagtagct ttatcatagt
     7021 tctttgacca ttaagggtaa atagataata aattcagtaa actcaccttc tatgctgttg
     7081 acgaagattt ttcctttgtg cgcttcgatt acctgctgca cgaaattcag acccagtccg
     7141 aaaccagacg ctttcttctt gttgctcctg cttccagccg ccgcccgctc gtatttgttg
     7201 aagatgctgc gctgatcctt ttccgatatg ccaagaccat tgtcgtatat cttgatgatg
     7261 gaataaaggt cgtttttcga tgacgagacg cgtatgtcca cacgctcttt ggaatatttg
     7321 atggaattat ctatcaggtt actgaatacc tcttcgatgt attccgcatc ggcgtatatc
     7381 tccggtgttt gcaaatcaaa ctcgaacgat acgggcttgt gtgatttcac cttgaactta
     7441 tccgccagcc tgacgagcat cggctccagc gcaatctttt cacactccat cttcatcttc
     7501 ttgttctcca gtttcgatat ggtgagcagc ttgttggtca gtgtcagcag gcggtccgcc
     7561 tcttccttgg cgacattgaa gaatttctct tttgtctccg gcttgtcatc cagccttccg
     7621 ctgtgcagga agctcaatgc cgtgaatatg gtggtaagcg gagttttcat gtcatgcacc
     7681 attgcatagg aaaagtcttc acgtatttga aagatttttt tttgtttaga tacaattttg
     7741 acttggtata taatgcatcc gataacaaaa atcataataa tgatagttga tattaaaagg
     7801 atattcattc gttcaaaaat tgatatttgt ggattttcaa gaaccagttg tattcctttt
     7861 gataaatcta cttttatagg aataactttg gattctattg tagtcaatgc gtttttttga
     7921 ttacatttat tgtaacttgc ataaatttct tcattcttag ggtttatgat tctaatataa
     7981 aaacgattgt tgatgttttt ttcctttagt aagagatttg taatggaatc aattctttga
     8041 agtgataatt tatatcctaa ttttgatatt ccttcatata gataagttga ctgtggaata
     8101 gaatcagtgt ttgcaccacc tattattcgt gttccttctg gaagttgttt tgctataatg
     8161 cttgtttctt tttttaatgc ttcttctatt atattattgc attcaatgaa aatgttattc
     8221 ttaataagga tataggtatt gttaagccat acatattgca atgataatat agatataata
     8281 cctaaaagtg taaagcataa tatgaaatta ttgtatctca ttttttgagg caaagataat
     8341 aaataacatt tagataacat agaaataaca tataatgaat ctgtttattt tgatatttgc
     8401 agcatcttaa taataaaaaa tatatagagt atgaaacaga tacaagattt agaaaaaaat
     8461 gaaatgattg aaatttttgg tggtgaatgg atggttttaa atggtgaatg ggtctatgta
     8521 gatgtaacgc gaggaaaaga tgattaaatg atatgtatga aaatcattaa cctaacgata
     8581 acataaaggt aacataattc ccaataatgt tgttttatct ttgcatcagt aaaacaaaca
     8641 aagagtttaa taaacaatta aatagaaaag cgtatgaaaa agaatgaatt gaaaacttta
     8701 gagattgaag aattgaaaaa cgtgaatggc ggagtagcac ctggacctaa cggtgaaagc
     8761 tgtacggaac atggactgcc ggattttttg aaaaacacga tcctcttgga tattcttaaa
     8821 catagatagt ggaagaatgg tatttgagag aattaaaaat aaaatagtat taacaaataa
     8881 acttattgtg tatgaaagaa ttgaacaaag atgaggacct gtcaattaca ggtgggtatt
     8941 ttcctccaac agaggaacag ttggaaaaat tgaatcctat tgagagaatt atcatttgtt
     9001 ggtaaagtaa gaatgttgtg tatggaaaag aatgaaatga tgcgtactat gagtctgcaa
     9061 gaacaacagg aaatcaatgg cggtggagcc ttggatattt tgataaacct taaatccgca
     9121 actccattcc cgaagtgcta cctacataaa gagaaatgga cttttgattc gtaagataac
     9181 cattaagtcc tcgcgtccgt ttcaatgcgc ataccatccc cttaccccat aaagcgactt
     9241 gaggcaatac gcaatcagtg gccatcaagt gatgtaaatc atccggaaga agttttgaag
     9301 gcttctgcat atgcatggtt gtcggtgtag atattcagca cacattgcct tgcggtctta
     9361 atccacttgg caggtactga aatgaatttg aagacaaacg tcttgatacg gctggtttcc
     9421 ttgagcccga acttcttcac ttcaatcctt tgcatgatgg ccttgtagaa attgcgtatc
     9481 agtgccgtca ggagcaggaa cacggtattt tccgccatga aggatttagg cagtctgtcc
     9541 catccaaacc cattgttcat gtcatcaaag acgcgttcct tgccaccgcg catgttatag
     9601 aactccacga tgtccctcat ggatgattcg taatcgttgg tcaggatgca gcggtatgta
     9661 tattcccccc tcccacaggt ccggtccact gcccatgcgt ctctgtctct ggattaccag
     9721 gcgatacggt ttgcccttcc acttctcaac gagaatggag ttcaactcaa acacgatgcc
     9781 gtttatctct tccttcttcc accctctgag cgcgaagatg tcatcataga gcgagcagca
     9841 gcggttggcg cgtatgtaga atgtcctgca atgcttcctg acctcatcca caatgtcttc
     9901 agagcatgag ccgcagtcgg ccctgaagcg tttgactgtc agcttcttct cttcaagtct
     9961 ctccaaaatc ctctttagcg tgtccttctg gtgaaagcgt acattggtgt tgccgtcgct
    10021 gttctctatg ccgacaatca tgtcgccgat aacggccaca ccggacctgt aaccaagaaa
    10081 tttcttgtac gtgggctttg catcgtactt ctccgcctca atgaactggt ggtcaaagtc
    10141 aacgtcatac tccccgccct ctttcaactg ccctgtggac aacaggcaat tcaggagcaa
    10201 tgtgttgagt gtgtctgccg tattgaaatc ataggacttt ccggcatcag acgtgtatga
    10261 gatgttttcc cgggtcagtt cgtttattgc cctaaggatg gtgtcggcgc tacaggtgcg
    10321 gagtgtgggg tgaagggaaa gatgactcat taagtgggcg gtgacatcct caacgcaaga
    10381 accgccgcag aagtaaacgc ataggaggga gcggatgatt tcgctgtatt gataaccata
    10441 gagtttgcat ctcaacccaa gtgttgagtc aattgtagag gagagaaggg aggtaaattg
    10501 ctccatgatt ggaaatatgc ctccaaaagg agtgagtctt tcggatttta ttgctacctt
    10561 tgccatgcct gttgcggttt tctttgtctt tggattcgca acactaaggt aagtgaaaac
    10621 gctgacatgg caaaaacctg ggcaacaaaa tgttgctcag gaacttataa aaataattat
    10681 caattatgtt gcggaattaa ggataaatac gattgtagac gttttgaatg gaagaatgcc
    10741 tgtatatgtt taatgcatta aaatttaata gtatgaaaga actgaagtgg atgaaatgag
    10801 attgattgat tgtgagataa ttaaattgat taaaaatatt taaacggaaa aacagtatga
    10861 aagaaaatgt atttatggtt gagttaaatc agaaagaaat gagtgaagta aatggaggag
    10921 gtatttggac agaagtgttt aaagctctta ttgcatctta tgagatggca agtgatttta
    10981 aggaaggatg ggattctgtt ccagatcttt aattgattta tgaaactgat gaaaataatt
    11041 atctattaga aaggagtatt tatgatgaag aatgaatcat atgtagagct tagtaagaaa
    11101 gaaaattcag aaatctatgg tggtaaaagt tttatgacta ctataggtga actttgccat
    11161 aagggatgga atgaagtaaa atcatggttt cgataaatgt taaatagatg aagaagatgt
    11221 agtataaatg tgaactttac tatatcttct tcatttggat tatttgctta tgtgttatat
    11281 tgtgaaaaaa aatagagttc cattatgggc tgatttgttg atatttttag tgtttctttt
    11341 tattgcatct ttgataggag tagagagcac attgtcattg ataggttcaa cagaatttga
    11401 aagtgttaaa tatttctttt tgtctacaat tatttcttct ataattgtct tattagctat
    11461 tttacttcaa cattatgtta tagacaaacg acctttaagt gaattgggtt tatgtactac
    11521 tcactttgta tggaaacatt caagtatggt tgttgtgtgg acgtttatcg tgtttgttat
    11581 tggttttttg atttgtttat taagtggtga tgtctctatt gtatcagtat attggaattt
    11641 gaaagacttg tctttgagtc tattgatgtt tacttttggt gctttctatg aggaaattat
    11701 aatgagagga tatctattga cacgtttatg ccgatctgga ctaaatgtat ggctatgttt
    11761 aataataact gcaattgttt tctctgcaat gcatttagca aatcctaatg tgaatgtttg
    11821 ttctgttgtt aacctctttt tgtttgggat tttagacgga tgtatttttt tatatactaa
    11881 aagtctatgg gtgtctgtaa tagctcattg tgcatggaat tggatacaag gatcaatttt
    11941 ggggtttaaa gttagtggtt gtgaattctt tcagcccatt ataaatttgg atatgccgtc
    12001 ttataattta gtaaatggcg gattatttgg atttgaaggt tctataatct gtacgatatt
    12061 attaatacct tttattatca tttttataaa ccttctttca aaaagtattg cgaaagacga
    12121 attccagcat taacctaacg ataacataag cataacatat cctctttttt agaacggtta
    12181 cttttgtcct gtgaaaagga aacagaagta accgttttta atttaaaaaa gatatgctat
    12241 taccgaacga atggatagag aacagtatcg agacgtacat ctatcagcac acaacgaaat
    12301 cgcaggtgat ctactgggtt gtcctgcttg ccgtgaccgt cacattagtg gcacttccct
    12361 ttgtctatgt ggatatctcc gtacagggaa gcggcgtagt gagaccggtt gcggaaaagg
    12421 ctgaaatcac ttcctccatt accgaaattg tggattcggt attcgtgaag gaaggtgacc
    12481 aggtgaacaa gggagatgtg attctccggt tccgcaccaa caattcggac tacaagatca
    12541 attaccagac cagccggttg aacgactgca gcgcacagct tgccgacctt gcctttttag
    12601 cgaagggcga acgtccggaa cggttcagtt ctccggtaag gcagcaggaa tacgcctatt
    12661 tcatccggaa gaaacaggaa ctggaaacgg cactggcaca ggcggaaaag gaatacaccc
    12721 ggaacaggac gctttttgag aagaaggtca tttcggaaga ggaatatgac agttactact
    12781 tcaagttgaa aagccagcag aacgaactgg catcgctggt acagagccag ctcagcacct
    12841 ggcaggcaga ccagaacacc taccggaaca catacaacga gatgaactcc agcctgaatc
    12901 aggagataaa ggacaaggac atgtatattg tgcgcagccc ggtggacggg acggtagacc
    12961 agttctccgg cgtgtaccgc ggaagcagca ttcaggcagg tcagtcgctg gcggttatca
    13021 gtcccgactc cacgctctgc ctggaggtct atgtcacgcc gagaaacatc gggtttatga
    13081 gcgtgggtat gccggtgaac gtgcaggtag aatcgttcaa ttacaacgaa tggggaacga
    13141 taccgggaag agtaaaggat atatcatcgg acttcctgac ggacagccaa ggcaattcct
    13201 tctacaaggt gaaatgcgag atggagcgtg attatctcca gctgaagaac ggaagggtag
    13261 ggaagctgaa aaaaggaatg acggtgaatg cgcatttcat ggtgacacgc cgttcgctgt
    13321 tcgacctgct ctatcagaag atggacggat gggtgaaccc gaaacagtat gagaacgaaa
    13381 caatggtagc gaaattaaac tgaatggaaa aacggaaaaa acagaatgac tatgtataag
    13441 aaaggaatca agataaaaca gcatgacatt acggactgcg gcgcggcatg ccttgcctct
    13501 gtctgcgcac attacgggct tcagtttccg gttgcccgca tccggcagta cgcgttcacc
    13561 gaccagaaag gaacaaacgt gttgggactg atagaggctg ccaaccggct cggactttcg
    13621 gcaaaaggcg tgagggcaca gtttgaagcg cttgccatcg ttccgaaacc gaccatcgcc
    13681 catgtaatcg tacatgagca cctgcagcac ttcgtggtca tctataaggt ggaaaaggga
    13741 cacatcacct atatggatcc gggagacgga aggatgcaca aggtgacgga cgaagagttt
    13801 aagaggatgt ggacgggcgt gcttgtgctg atggaaccgg aagagacctt caagaagggg
    13861 aacatgaaaa ccagcatgac gcggaaattc ttctcgctgc tggcaccaca caagagcgtc
    13921 atgatgcagg cggtgttcgg ggcgttggta tacagtattc tcggactgtc cacctcggta
    13981 tatgtaggca agattaccga ttacgtatta gtggacggaa acatcaacct gctcaacctg
    14041 atgggcgtgg tgatgattgt catcctgatt ctccgcacct ttatcggagc catgaagagc
    14101 atcctggcac tgaagaccgg acagcgcatc gatgccgcct tgatactggg atattacaag
    14161 cacctgctga cgctcccgca acagttcttt gacacgatgc gtgtgggtga gatcatctcg
    14221 cgtgtgaacg atgcggtgaa aatccggaac ttcatcaaca acgtgtcgct cgatttggtg
    14281 gtgaacatga tgatcctgct tttctccgta ggtctgatgt tcgtgtattc gtgggagctt
    14341 gcccttgtga cgctggcatc cgcaccgctt ttcctgctta tcttctgggg gttcaaccgg
    14401 ctgaaccgga aataccagcg cggcattatg gagagcagcg cggacttgga ggcacaactg
    14461 gtggaatcca tcaactccat ctccaccatc aagcgtttcg gcatcgagga ctttgccaac
    14521 ctgaagacgg agacccgctt cgtgcatctg ttgaagaaca cgttccgcag catttacgga
    14581 gcgatcatgg cacagggtgg catccaattc gtctccacag ccatcaccat agcggtgctc
    14641 tggatgggaa gtgtgctggt catcgacaag gaactgacac cgggaacgct gatggtgttc
    14701 tattcgctca tcagctacgt catctcgccc atcggctcgc tgatatcctc caaccagacc
    14761 attcaggacg cactgattgc agccgaccgc ctgtttcaga ttatggacct ggagcgtgaa
    14821 caggacgaca gccaaaagat agagcttgaa ccggacatga tcggtgacat cacgtttgag
    14881 aatgtgtcgt tccgttacgg ttcgcggaaa gaagtgttca aaggacttaa cctgaagata
    14941 gaaaaaggaa agaccacagc tgtcatcggt gagagcggtt cgggaaaaac cacgctgatc
    15001 tcccttttgc agcatatcta tcccatccag tccgggcaga tccgcatcgg cgaatatgac
    15061 atcgcccaga taagcaatcg gagcctccgc cgcagggtgg ggactgttcc gcagcagatt
    15121 gagctgtttg ccgggacaat catcgagaac attgcggtgg gagacctgca gccggacatg
    15181 aaacggattg tagaccttgt ggaacagctc ggactgaagg atttcatcga gcgtctgccc
    15241 aacggataca tgacctatat cggcgagcac ggtgcttccc tttccggagg tgaaaggcag
    15301 cgcattgcca ttgcacgcgc cctgtataag gaaccggaga ttctgatttt tgatgaagcg
    15361 acctcctcgc tggattccat atcggagaag catgtgaagc agacgctgga cgcactggct
    15421 aaacggggaa agaccgtcat tgtcattgcg catcgcctga gcacggtgaa gaacgcggat
    15481 aggattgtgg tactcgacaa gggtcaggta gccgagacgg gtacgcacaa ggaactgttc
    15541 aattctggcg gaatctacag ccggttgtgg aacgagcagt ttgaccagtt ggattaatct
    15601 gtttccattc ctataatccg atattcgggt tgtaggaatg gatttttctt aaccttttga
    15661 taactttccg ataacatcgt ccgtggcttt gtctgtctac ttttgtagag cgaaaaacga
    15721 ataagaaagg acgaaatatg aaaggattag tatctatact ggcttttgcc ggattattag
    15781 cctgtcaggg aaacgtacag gcacaagtga aaaaatggac gcttgcagag tgtatcgact
    15841 atgcagtgac acacaacatt gaggtaaagc aaagcgataa ccagattcag aacttgaaag
    15901 tgcagaggaa tacattaaga aacagttttc ttccggatct gaatgcaggt gcctcgcaga
    15961 acttcacatt cggacgatcg ctgaaccaga acaacacgta tgaggacagc aacatacaga
    16021 actcgtcttt ctctgtaact acggaaatcc cgatatttgc cggattcaag cggacggcat
    16081 ccattgcgca gaaccgcttc gacctgcttg ccgcagaggc gaaccgggaa ctgatagaga
    16141 acaacctgtc gctgaacgtg gctggagcct atttccagat tcttctgaac aaggaaatct
    16201 accggatagc attggagcag atacagttga ccaaggaaca ggaaacctgc acgcagcttc
    16261 ttatcgagaa cgggaaggct gccgaatcac aactttatga tgtgcgtgca cagctggcgg
    16321 atgacgaact gaccgctacc gaagcgagaa attccctccg gctcgcttat cttgacttgg
    16381 cacaactgat ggagctgaaa gggcatgaac agtttgacat cgattcgctt ggcggagaga
    16441 ttgccatcgc cgacacgctg agtccggtga gcatctatca gtccgcccta acctgtatgc
    16501 ctcagatacg tcaggcatat tacaccctgc agagcaagac aaaaggcatc cggatagcca
    16561 agtccggata ttacccgacc ctttcattcg cagccggaat caacacgaac tattacgaca
    16621 acgggagcgg acttggtgag acgttccaga ggcagcttaa caacaacatg cagaaaagcc
    16681 tgtgctttac aatcagcatc ccgttgttcg accggttttc cacacggaac caggtgaggg
    16741 cggcacgtat cgatgaggat aatgcgagac tgtcattgga aaacgagaaa aagcagttgt
    16801 acaaagacat cgagcaggct tatatggatg cgatatccgc attcgagaaa taccgttcca
    16861 ccacgaaagc agtaatagcc aaccaggagg cgcaccggta tgccttggaa aaatatgcag
    16921 ccggtaaatc tactgtattc gaatacaatg aaatcaagat gaaacttgcc gacgcacttt
    16981 cgcaacagtc acaggctaaa tatacctatc tgctgaaaga ccgtatactg gctttctatt
    17041 cctgcttttc actaacagat taacagcctt gtaattatgc attcaataaa gataaatctc
    17101 gatgtcgttt taaataaaag aggaatgacg ttgaatgaac tttcggaaaa aacaggcgtg
    17161 tctatagcca acctttccaa cctgaaaaac aaccgtgtcg tttcagtcag gttttctacg
    17221 cttgggagaa tctgtaaagc cttggaatgc cagcctgccg acatcttaaa gtatgaagat
    17281 gattaactta atgataacat tctgataacc tgaaagggga tacatccttc ttacctttgt
    17341 gtcagtaaaa ggaaataaag acgaaacaat aaaaaatagt aagatatgga aattattaca
    17401 gcaacaacga tttttttagc gtcattgaac gtatatggcg agtgtgggtt tgcatacaat
    17461 gcagaaactt ctgaggatgg aattgtcaca gccaaggctg tgtaccataa gtcggtatgt
    17521 ggaaagtatc tgtctccgac tctgaaatac aactatgtgt atgacggaga gcaacgtctg
    17581 gcacagaaag aagtgttgaa gtggaactgc gtaacagaga aatgggataa atcgcacatt
    17641 ttgaattaca tgtatgatga aaacggatat accattgagt atgccgtatg ggacagtggc
    17701 aaacaggaat acgctgatgt ggttgccaag cagacttatc atgaaagcat tgacggtgcg
    17761 ctttatatcg ctttgtatag atgggatgat tccgggaacg attgggtgaa acagaatgac
    17821 atggtcgcca tgaacctgtc aggcgaactt ctgacatctt ttgaatttga attataataa
    17881 aatgtataac aataaaatga tgaatttatg gaaaagaaaa atttagaacg gaaagtcaga
    17941 ctgattgcaa ttgaagaaat gagaaatgtg aacggcggag cgaacatcgt agccggggac
    18001 gaattttcac aactgaaact gccgattggc atgcgaaaga aattctaagc tgatgtcgtt
    18061 ttgaaaaaaa gaggttggat tggataataa attgaatgtg tgaatccttg tctgtatgtt
    18121 tttgggatgc ctgtgtgtgg catccctttt tttatggaaa ctaaactatg gagcatatct
    18181 ttctcccttg tcgcttaaat atagatctat ggcttcgttg aatgcctgaa gtaaggtcat
    18241 tccgttgtct gttgcatatc gtttcagccg gttgtggcgt gaagggtctg ttatgtaatt
    18301 gcaggtttta tatttgggct tttcttgtgt acgtaaatcc gattgcttta ccgctactgt
    18361 cgttggtctt accaatgaac ttagcccggc tttcatgttt tctctcaggt tgttcctttt
    18421 gttttccata cggttgtatt aattgaacgt tgattctttt ttaagaaatt catcacaaaa
    18481 tgaggcataa tcttccgctc ctgaagattt tggcgcatag tggaatatat catgtttagc
    18541 agctgttgct tctccgatag cgacattggt tcggattgta gtagtgaaca catccccttg
    18601 aaaagtgtca cggattatct cttgtatatc ctggttgaaa tttttccgtc tgtcgtattt
    18661 ggtaatcagt attccagaaa tacgcagttt tggattcagg ttgtttttta cttcatggat
    18721 gacgtttgtt agcctgccca ttcctcgcat tgctaagtat tctgcttcta cggggataat
    18781 gatgcaatcc gaagcagtca tcgcgttgat agtcagtata gataaggatg gagggcaatc
    18841 tataagaata taatcatatt gttcttgtac ctgactgatc aatttgtgaa gaatctgctc
    18901 ccgtgcatac ttttgcatta tttccatttc tattgctgac atatccaaac atgacggtac
    18961 aatatccaga ccgtcctcat tctttacaat cggaagcggg atgtagcctc tcatggcttg
    19021 ataaatggta tcgtcaagtt ctgtagaaac tcctaggcag tccgtcaggt ttgactgtgc
    19081 atccatatca atgagcagta cccgtttccc ccgaatttgc agtgctgcgc ccaaattagc
    19141 cgcggttgcc gttttcccga cacctccttt gtggttgatt attgatacta tttttgccat
    19201 acagttgatt ataaatgcta actgaaaaac taaattacta aaattagttg attagtggca
    19261 aaattactat taaatgcaga
//
