LOCUS       NC_009465            1022154 bp    DNA     circular CON 10-JUN-2013
DEFINITION  Candidatus Vesicomyosocius okutanii HA, complete genome.
ACCESSION   NC_009465
VERSION     NC_009465.1  GI:148244169
DBLINK      Project: 59427
            BioProject: PRJNA59427
KEYWORDS    .
SOURCE      Candidatus Vesicomyosocius okutanii HA (Candidatus Vesicomyosocius
            okutanii str. HA)
  ORGANISM  Candidatus Vesicomyosocius okutanii HA
            Bacteria; Proteobacteria; Gammaproteobacteria; sulfur-oxidizing
            symbionts.
REFERENCE   1  (bases 1 to 1022154)
  AUTHORS   Kuwahara,H., Takaki,Y., Shimamura,S., Yoshida,T., Maeda,T.,
            Kunieda,T. and Maruyama,T.
  TITLE     Loss of genes for DNA recombination and repair in the reductive
            genome evolution of thioautotrophic symbionts of Calyptogena clams
  JOURNAL   BMC Evol. Biol. 11, 285 (2011)
   PUBMED   21966992
  REMARK    Publication Status: Online-Only
REFERENCE   2
  AUTHORS   Kuwahara,H., Yoshida,T., Takaki,Y., Shimamura,S., Nishi,S.,
            Harada,M., Matsuyama,K., Takishita,K., Kawato,M., Uematsu,K.,
            Fujiwara,Y., Sato,T., Kato,C., Kitagawa,M., Kato,I. and Maruyama,T.
  TITLE     Reduced Genome of the Thioautotrophic Intracellular Symbiont in a
            Deep-Sea Clam, Calyptogena okutanii
  JOURNAL   Curr. Biol. 17 (10), 881-886 (2007)
   PUBMED   17493812
REFERENCE   3  (bases 1 to 1022154)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2007) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   4  (bases 1 to 1022154)
  AUTHORS   Maruyama,T., Kuwahara,H., Takaki,Y., Shimamura,S., Nishi,S.,
            Yoshida,T., Harada,M., Matsuyama,K., Fujiwara,Y., Sato,T., Kato,C.,
            Kitagawa,M. and Kato,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2006) Tadashi Maruyama, Japan Agency for
            Maine-Earth Science and Technology, Extremobiosphere Research
            Center; 2-15 Natsushima-cho, Yokosuka, Kanagawa 237-0026, Japan
            (E-mail:tadashim@jamstec.go.jp, URL:http://www.jamstec.go.jp,
            Tel:81-46-867-9520, Fax:81-46-867-9525)
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AP009247.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1022154
                     /organism="Candidatus Vesicomyosocius okutanii HA"
                     /mol_type="genomic DNA"
                     /strain="HA"
                     /db_xref="taxon:412965"
                     /country="Japan: Sagami Bay, off Hatsushima"
                     /synonym="Candidatus Vesicomyosocius okutanii str. HA"
     gene            1..1293
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /db_xref="GeneID:5172626"
     CDS             1..1293
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="YP_001218864.1"
                     /db_xref="GI:148244170"
                     /db_xref="GeneID:5172626"
                     /translation="MSQTWSQCLNTLRDSIPLSQYSVWIQPLKALENKNTLSLLAPNS
                     QVLNYINKNLKPQIKNAVTQHNKNLKIFIGIACNPNTKQHTTPLFEDYTFNNLVLGNA
                     NQMAYGATKQIAENIKTSPYNPFIIYGKSGLGKTHLMQAAGHLAKEKNPNIKIIYVPL
                     MDFVRNITSSLRHNTIENIKNFYQSTDLLLVDDIHLIAGKEKSQEEFFHIFNFLFSGK
                     KQIIFTCDQPPKNIKSLEDRLKTRFSQGLNLHLTPPELEMRAAILLKKSQNKRININL
                     TEDTALFIASHIASNIRDLEGALLKLKAFVDFSKINHSFISKEIIESALGDLIKPQIK
                     NIDINDIQKEVAKHYALTISDLSSKSRKQHTVLARQMAMFICYELSSLSLTKIGKHFG
                     NRDHSTVLHAIKKIKEKHIENIEIKNDYELINIKLANL"
     misc_feature    1..1287
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /note="chromosomal replication initiation protein;
                     Reviewed; Region: dnaA; PRK00149"
                     /db_xref="CDD:234667"
     misc_feature    10..192
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /note="DnaA N-terminal domain; Region: DnaA_N; pfam11638"
                     /db_xref="CDD:221153"
     misc_feature    325..741
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    385..408
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(388..411,574..576,676..678)
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    562..579
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    712..714
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    1012..>1206
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /note="C-terminal domain of bacterial DnaA proteins. The
                     DNA-binding C-terminal domain of DnaA contains a
                     helix-turn-helix motif that specifically interacts with
                     the DnaA box, a 9-mer motif that occurs repetitively in
                     the replication origin oriC. Multiple...; Region:
                     Bac_DnaA_C; cd06571"
                     /db_xref="CDD:119330"
     misc_feature    order(1081..1083,1105..1110,1129..1131,1147..1155,
                     1180..1194,1201..1203)
                     /gene="dnaA"
                     /locus_tag="COSY_0001"
                     /note="DnaA box-binding interface [nucleotide binding];
                     other site"
                     /db_xref="CDD:119330"
     gene            1507..2610
                     /gene="dnaN"
                     /locus_tag="COSY_0002"
                     /db_xref="GeneID:5172247"
     CDS             1507..2610
                     /gene="dnaN"
                     /locus_tag="COSY_0002"
                     /EC_number="2.7.7.7"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III beta subunit"
                     /protein_id="YP_001218865.1"
                     /db_xref="GI:148244171"
                     /db_xref="GeneID:5172247"
                     /translation="MNIQLRVKELLEPLQTVISVIEKKQTLPILAHVLIQLENNLLTL
                     TTTDMEIEIKTSQIIKNKEEISFTVYAKDLINIIKKLPENTIIKFIINNSKIYIKVNK
                     NSFELNTFRHQDFPSLPKIKNKKNITIKRKILKNLIEKTSFSMGNQDIRAYLNGLYFE
                     INKNNIVVVTTDGHRLSIGKIKQANNSLNKKTVILPRKSIIEFTKLLNKNEHEEVNIY
                     TSNNYFYLSTNNTTIISKLINSKFPNYLPVIPTDFNNTIIINRLDFLNSLQQASIFVE
                     EHTKGVKLIFKNSQLYIFSNSERGQAKTQIKTKNFNKKIEIAFNINYLISILEKLNTN
                     EINMIIPNGKNKSCLLNSINDDIYQYIVMPMRL"
     misc_feature    1507..2607
                     /gene="dnaN"
                     /locus_tag="COSY_0002"
                     /note="DNA polymerase III subunit beta; Validated; Region:
                     PRK05643"
                     /db_xref="CDD:235541"
     misc_feature    1507..2604
                     /gene="dnaN"
                     /locus_tag="COSY_0002"
                     /note="Beta clamp domain.  The beta subunit (processivity
                     factor) of DNA polymerase III holoenzyme, refered to as
                     the beta clamp, forms a ring shaped dimer that encircles
                     dsDNA (sliding clamp) in bacteria.  The beta-clamp is
                     structurally similar to the trimeric...; Region:
                     beta_clamp; cd00140"
                     /db_xref="CDD:238082"
     misc_feature    order(1576..1578,1720..1722,1741..1743,2098..2100)
                     /gene="dnaN"
                     /locus_tag="COSY_0002"
                     /note="putative DNA binding surface [nucleotide binding];
                     other site"
                     /db_xref="CDD:238082"
     misc_feature    order(1723..1725,1732..1734,1810..1812,1816..1818,
                     2323..2325,2413..2418)
                     /gene="dnaN"
                     /locus_tag="COSY_0002"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238082"
     misc_feature    order(2017..2019,2023..2034,2464..2466,2593..2604)
                     /gene="dnaN"
                     /locus_tag="COSY_0002"
                     /note="beta-clamp/clamp loader binding surface; other
                     site"
                     /db_xref="CDD:238082"
     misc_feature    order(2017..2019,2023..2028,2248..2250,2353..2355,
                     2392..2397,2473..2475,2593..2604)
                     /gene="dnaN"
                     /locus_tag="COSY_0002"
                     /note="beta-clamp/translesion DNA polymerase binding
                     surface; other site"
                     /db_xref="CDD:238082"
     gene            2711..5128
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /db_xref="GeneID:5172278"
     CDS             2711..5128
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /EC_number="5.99.1.3"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit B GyrB"
                     /protein_id="YP_001218866.1"
                     /db_xref="GI:148244172"
                     /db_xref="GeneID:5172278"
                     /translation="MSKKQSQNSQEYKASSIKVLRGLDAVRKRPGMYIGDTDDGTGLH
                     HMVFEVVDNAIDESLAGYCSKINIIIHEDKSVSINDNGRGIPIDIHPEEGISAAEVIM
                     TILHAGGKFDNNSYKVSGGLHGVGISVVNALSEWVKLTVYRNNKIYYQHYNKGVPEKP
                     IQVIGKSNKTGTIIHFKPNINIFSNTEFNYDILANRIRELSFLNSGVHIGIEEFSTEK
                     KDIFKYKGGIKSFIKHLNKTKTPIHNDIIEINTQREKIKIVVALQWSDSYQQSIYCFT
                     NNIPQRNGGSHLAGFRGGLTRTVNNYIDNSDIAKKEKNSITGEDTREGLTAIINIKIP
                     DPKFSSQTKDKLVSSEVRAPIESIINDKLNDYFLENPKEAKIIIKKILDASRARNAAR
                     KAREITRRKGLFDISSLPGKLSDCQTKNPVESEIFLVEGDSAGGSAKQGRNRRTQAIL
                     PLKGKILNVEKSRFEKILSSAEVGTLITALGCGIGKEEYNLNKLRYHKIVIMTDADVD
                     GAHIRTLLLTFFYRYLPELIENGYLYIARPPLYKIKKGKQERYLKNDQELNDYLLQEG
                     INNSYLFVSKKTPPISGIELEFLIKEYYKINKIFDKLSKHYNLNLLKAISNSKPIDDL
                     TNHKNMNTWCTNLTKNLNKNLTLEKTHKVIFNKNTNEVEYTLYVYGVNIDHTILNSVF
                     FNSFDYQSIKEFSKKIENVITQESYVKNINKKIRVQYFSHVVEFLMNNARKGQSFQRY
                     KGLGEMNPKQLWETTMDPEQRTLFKVKIEDSIISDEVFSTLMGDAVEPRRNFIEDNAL
                     SVNNLDF"
     misc_feature    2726..5125
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="DNA gyrase subunit B; Provisional; Region: gyrB;
                     PRK14939"
                     /db_xref="CDD:237860"
     misc_feature    2837..>3115
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    order(2855..2857,2867..2869,2876..2878,2942..2944,
                     2948..2950,2954..2956,2960..2965,3080..3091)
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    2867..2869
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    order(2954..2956,2960..2962,3080..3082,3086..3088)
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     misc_feature    3386..3859
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="TopoIIA_Trans_DNA_gyrase: Transducer domain, having
                     a ribosomal S5 domain 2-like fold, of the type found in
                     proteins of the type IIA family of DNA topoisomerases
                     similar to the B subunits of E. coli DNA gyrase and E.
                     coli Topoisomerase IV which are; Region:
                     TopoII_Trans_DNA_gyrase; cd00822"
                     /db_xref="CDD:238419"
     misc_feature    3539..3541
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="anchoring element; other site"
                     /db_xref="CDD:238419"
     misc_feature    order(3713..3715,3722..3727,3731..3733)
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238419"
     misc_feature    order(3731..3733,3737..3739)
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238419"
     misc_feature    3980..4324
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM)
                     nucleotidyl transferase/hydrolase domain of the type found
                     in proteins of the type IIA family of DNA topoisomerases
                     similar to the Escherichia coli GyrB subunit. TopoIIA
                     enzymes cut both strands of the...; Region:
                     TOPRIM_TopoIIA_GyrB; cd03366"
                     /db_xref="CDD:173786"
     misc_feature    order(3998..4003,4010..4012,4220..4222,4226..4228,
                     4232..4234)
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="active site"
                     /db_xref="CDD:173786"
     misc_feature    order(3998..4000,4220..4222)
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="putative metal-binding site [ion binding]; other
                     site"
                     /db_xref="CDD:173786"
     misc_feature    4901..5092
                     /gene="gyrB"
                     /locus_tag="COSY_0003"
                     /note="DNA gyrase B subunit, carboxyl terminus; Region:
                     DNA_gyraseB_C; pfam00986"
                     /db_xref="CDD:201537"
     gene            5149..6027
                     /gene="prkB"
                     /locus_tag="COSY_0004"
                     /db_xref="GeneID:5172433"
     CDS             5149..6027
                     /gene="prkB"
                     /locus_tag="COSY_0004"
                     /EC_number="2.7.1.19"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="YP_001218867.1"
                     /db_xref="GI:148244173"
                     /db_xref="GeneID:5172433"
                     /translation="MSNKHPVIIVTGSSGAGTTFVKRAFEHIFRKESINPLIIEGDSF
                     HKYDRNSMKKNVKKQEDLGNNFFSHFGPDANLFEKIEQTFKDYSETGKCDRRYYLHSI
                     KEANKHNQRLNTNLNPGEFSPWEKVGDGTDLLFYEGLHGVVVTDGVDMAQYGDLKIGV
                     VPSVNLEWIQKIHRDNTERGYSAEETVSTILRRMPDYINYITPQFSQTDINFQRVATV
                     DTSNPFIARDIPTPDESFIVIRFNDLDKTSVDFSYLCSMINGSFMSRRNTIVIPGGKM
                     SLAMEIILYPIIKKMI"
     misc_feature    5149..6024
                     /gene="prkB"
                     /locus_tag="COSY_0004"
                     /note="phosphoribulokinase; Provisional; Region: PRK15453"
                     /db_xref="CDD:237970"
     misc_feature    order(5182..5184,5197..5208)
                     /gene="prkB"
                     /locus_tag="COSY_0004"
                     /note="active site"
                     /db_xref="CDD:238977"
     gene            complement(6084..8531)
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /db_xref="GeneID:5171803"
     CDS             complement(6084..8531)
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /EC_number="6.1.1.5"
                     /note="leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA
                     synthetase; charges leucine by linking carboxyl group to
                     alpha-phosphate of ATP and then transfers
                     aminoacyl-adenylate to its tRNA; due to the large number
                     of codons that tRNA(Leu) recognizes, the leucyl-tRNA
                     synthetase does not recognize the anticodon loop of the
                     tRNA, but instead recognition is dependent on a conserved
                     discriminator base A37 and a long arm; an editing domain
                     hydrolyzes misformed products; in Methanothermobacter
                     thermautotrophicus this enzyme associates with prolyl-tRNA
                     synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl-tRNA synthetase"
                     /protein_id="YP_001218868.1"
                     /db_xref="GI:148244174"
                     /db_xref="GeneID:5171803"
                     /translation="MNIKYDVQKIEKQAQKYWKEKKSFEVIEDYSKEKYYCLSMFPYP
                     SGRLHMGHVRNYSIGDVISRFQRMQGKNVMQPIGWDGFGLPAENAALKNKESPAKWTY
                     KNINYMKTQLNQLGFGYDWAREITTCHPKYYRWEQWLFIKLFKKNLIYKKKAIVNWDP
                     VDQTVLANEQVINGRGWRSNALIEKKEISQWFIRITNYAEELLNDLDKLYGWPDPVKI
                     MQKNWIGKSIGLEITFSRRNSDPLIIYTTRPDTLMGVTYLAISFEHPLALESGKNNYQ
                     VQSFIEKCKTIQTSEILNEIMDKKGIDSGFKCIHPITNNEVPIWITNFVLMSYGTGAI
                     MSVPAHDKRDFKFAKKYGIFIKQVINKNESIDKGPIINKGKLFNSEEFSGMDFNQAYE
                     SIAKTLIEKNLGNKKINYRLRDWGISRQRYWGCPIPIVNCKYCGSVTVKVKDLPVILP
                     EKVKFYDVSSPIKKMPNFYQTICPKCGSKAHRETDTFDTFFESSWYFARHTCNNNNNA
                     MLDKRVNYWLEVDQYIGGVEHSILHLLYARFFNKLLRDEGLIKYDEPFKNLLTQGMVL
                     KNGVKMSKSKGNTVDPTKMIKKYGADTVRLFILFAAPPMQDLEWNNSGLEGAHRFIKK
                     VYRLVSIYINDSKDYIVNHLNINFLNKTQKHIRRKIHQNLVKITDDINRRYTFNTAIS
                     TLMESVDIINKFTKTDTQSIALRSESINIILLTLSPITPHICHYLWLKLGNKKAIINE
                     PWPKVDLKALIESEVQIIIQVDGKLRDKMMMMINTDKEILESEVLSNKNIIKFTKNKN
                     IIKIIIIHNKLINIVTK"
     misc_feature    complement(6174..8531)
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /note="leucyl-tRNA synthetase; Validated; Region: leuS;
                     PRK00390"
                     /db_xref="CDD:234743"
     misc_feature    complement(<7821..8432)
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /note="catalytic core domain of leucyl-tRNA synthetases;
                     Region: LeuRS_core; cd00812"
                     /db_xref="CDD:173906"
     misc_feature    complement(8376..8387)
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173906"
     misc_feature    complement(7335..7850)
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /note="Leucyl-tRNA synthetase, Domain 2; Region:
                     tRNA-synt_1_2; pfam13603"
                     /db_xref="CDD:222257"
     misc_feature    complement(6702..>7298)
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /note="nucleotidyl transferase superfamily; Region:
                     nt_trans; cl00015"
                     /db_xref="CDD:241550"
     misc_feature    complement(6804..6815)
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /note="active site"
                     /db_xref="CDD:173912"
     misc_feature    complement(6804..6815)
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173912"
     misc_feature    complement(6339..6704)
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /note="Anticodon-binding domain of bacterial and
                     eukaryotic mitochondrial leucyl tRNA synthetases; Region:
                     Anticodon_Ia_Leu_BEm; cd07958"
                     /db_xref="CDD:153412"
     misc_feature    complement(order(6444..6446,6456..6458,6465..6467,
                     6474..6479,6486..6488,6498..6500,6660..6662,6672..6674,
                     6681..6686,6693..6695))
                     /gene="leuS"
                     /locus_tag="COSY_0005"
                     /note="tRNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:153412"
     gene            complement(8528..9505)
                     /gene="pyrD"
                     /locus_tag="COSY_0006"
                     /db_xref="GeneID:5172446"
     CDS             complement(8528..9505)
                     /gene="pyrD"
                     /locus_tag="COSY_0006"
                     /EC_number="1.3.98.1"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase dehydrogenase"
                     /protein_id="YP_001218869.1"
                     /db_xref="GI:148244175"
                     /db_xref="GeneID:5172446"
                     /translation="MNNNLKNQFCGLFFNSPIVLLSGCVGFGKEYTNIDGFTNSDVGA
                     ICLKGTTLKRCLGNIPHRVTETPSGMINAIGLQNPGSDVVINKILPKLDKTETNFIIN
                     ISGSSFEEYGEITKRFDNTDIHAIEINISCPNIKKGGVTFGNDPNMSYRVVEICRRNT
                     TKPIITKLSPNQTDIAFSAQRCIDAGTDGLAVINTLMGMAINITTKKPIIGNNQGGVS
                     GPAIKPIALLKVYQVYQVSKHYNIPIIGQGGITTANDAIEFIIAGASAIGIGTALFYD
                     PLVCHKINHGISEYLNNNNLNSIDDLIGTLELNSTTSQCDTYLDKSRIL"
     misc_feature    complement(8594..9493)
                     /gene="pyrD"
                     /locus_tag="COSY_0006"
                     /note="dihydroorotate dehydrogenase (subfamily 1) family
                     protein; Region: pyrD_sub1_fam; TIGR01037"
                     /db_xref="CDD:130109"
     misc_feature    complement(8588..9484)
                     /gene="pyrD"
                     /locus_tag="COSY_0006"
                     /note="Dihydroorotate dehydrogenase (DHOD) class 1B
                     FMN-binding domain. DHOD catalyzes the oxidation of
                     (S)-dihydroorotate to orotate. This is the fourth step and
                     the only redox reaction in the de novo biosynthesis of
                     UMP, the precursor of all pyrimidine...; Region:
                     DHOD_1B_like; cd04740"
                     /db_xref="CDD:240091"
     misc_feature    complement(order(8672..8677,8681..8683,8846..8848,
                     9275..9277,9311..9313,9317..9322,9338..9340,9362..9364,
                     9404..9406,9413..9418))
                     /gene="pyrD"
                     /locus_tag="COSY_0006"
                     /note="heterodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240091"
     misc_feature    complement(order(8693..8698,8759..8761,8849..8851,
                     8921..8929,9005..9007,9110..9112,9119..9121,9290..9292,
                     9359..9361))
                     /gene="pyrD"
                     /locus_tag="COSY_0006"
                     /note="active site"
                     /db_xref="CDD:240091"
     misc_feature    complement(order(8693..8698,8759..8761,8849..8851,
                     8924..8929,9005..9007,9119..9121,9290..9292,9359..9361))
                     /gene="pyrD"
                     /locus_tag="COSY_0006"
                     /note="FMN binding site [chemical binding]; other site"
                     /db_xref="CDD:240091"
     misc_feature    complement(order(8591..8593,8600..8602,8720..8725,
                     8732..8734,8822..8827,8831..8839,8846..8848,8882..8890,
                     8897..8917,8990..8992,9074..9076,9302..9310))
                     /gene="pyrD"
                     /locus_tag="COSY_0006"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240091"
     misc_feature    complement(order(8921..8926,9113..9115,9119..9121,
                     9290..9292))
                     /gene="pyrD"
                     /locus_tag="COSY_0006"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240091"
     gene            9545..10195
                     /gene="bioD"
                     /locus_tag="COSY_0007"
                     /db_xref="GeneID:5172479"
     CDS             9545..10195
                     /gene="bioD"
                     /locus_tag="COSY_0007"
                     /EC_number="6.3.3.3"
                     /codon_start=1
                     /transl_table=11
                     /product="dethiobiotin synthase"
                     /protein_id="YP_001218870.1"
                     /db_xref="GI:148244176"
                     /db_xref="GeneID:5172479"
                     /translation="MKGLFISGSGTNVGKTFIAQYLIKFLTNILKVRVRKPVESDCKN
                     KNGKLIPKDALLLSKACNIIESIDKICRYKFQACSSAQIASQALGLKLTLDDLVDACI
                     ADEFVVVEGAGGLLSPIATKTLNSDLVQAINVPVVLVIKDELGAVNQALLSINAAQHY
                     KLNISMVVLNQIYPNLLGNEKEITQYTNANIVVFNQNDLKSFERQIEKILLADLIK"
     misc_feature    9545..10105
                     /gene="bioD"
                     /locus_tag="COSY_0007"
                     /note="Dethiobiotin synthetase [Coenzyme metabolism];
                     Region: BioD; COG0132"
                     /db_xref="CDD:223210"
     misc_feature    9548..10120
                     /gene="bioD"
                     /locus_tag="COSY_0007"
                     /note="AAA domain; Region: AAA_26; pfam13500"
                     /db_xref="CDD:222178"
     gene            complement(10184..10522)
                     /gene="sspB"
                     /locus_tag="COSY_0008"
                     /db_xref="GeneID:5172454"
     CDS             complement(10184..10522)
                     /gene="sspB"
                     /locus_tag="COSY_0008"
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein B"
                     /protein_id="YP_001218871.1"
                     /db_xref="GI:148244177"
                     /db_xref="GeneID:5172454"
                     /translation="MMLSIAPYLIRAYHAWTEDAKLTPHILVDCTYSSVIVPKQFIQQ
                     NKIVLNIASNATYNLIISNDNLSFKARFSKKLINIFVPINAINSIYASENGKGMFFKT
                     EEKPNLKLLD"
     misc_feature    complement(<10211..10522)
                     /gene="sspB"
                     /locus_tag="COSY_0008"
                     /note="Stringent starvation protein B; Region: SspB;
                     cl01120"
                     /db_xref="CDD:242314"
     gene            complement(10519..11154)
                     /gene="sspA"
                     /locus_tag="COSY_0009"
                     /db_xref="GeneID:5172057"
     CDS             complement(10519..11154)
                     /gene="sspA"
                     /locus_tag="COSY_0009"
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein A"
                     /protein_id="YP_001218872.1"
                     /db_xref="GI:148244178"
                     /db_xref="GeneID:5172057"
                     /translation="MLTKPNPASTTLYSSPKDIRSHVVRFIMAEKNIEREVLNLKIEE
                     IPEEILELNPCQSLPTLFDRGIVLYDLSVVMEYLDERFPFPPLLSVDPIEKSEKRLLI
                     FRFTRAPNCWFELADIIESGSKKNADKARKVLKSNLIELVPLFAYKPFFKSDDMTIVD
                     ACLGALLWRLKKLEIELGKPGKSVIDYANRLFTRDSFKASLTDCEKEYNEI"
     misc_feature    complement(10534..11124)
                     /gene="sspA"
                     /locus_tag="COSY_0009"
                     /note="stringent starvation protein A; Provisional;
                     Region: sspA; PRK09481"
                     /db_xref="CDD:236537"
     misc_feature    complement(10909..11124)
                     /gene="sspA"
                     /locus_tag="COSY_0009"
                     /note="Protein Disulfide Oxidoreductases and Other
                     Proteins with a Thioredoxin fold; Region:
                     Thioredoxin_like; cl00388"
                     /db_xref="CDD:241832"
     misc_feature    complement(10552..10881)
                     /gene="sspA"
                     /locus_tag="COSY_0009"
                     /note="C-terminal, alpha helical domain of the Glutathione
                     S-transferase family; Region: GST_C_family; cl02776"
                     /db_xref="CDD:243175"
     misc_feature    complement(order(10648..10650,10660..10662,10669..10674,
                     10681..10683,10837..10839,10858..10860))
                     /gene="sspA"
                     /locus_tag="COSY_0009"
                     /note="N-terminal domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:198286"
     misc_feature    complement(order(10735..10737,10834..10836,10843..10848,
                     10855..10860))
                     /gene="sspA"
                     /locus_tag="COSY_0009"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:198286"
     misc_feature    complement(order(10648..10650,10657..10659,10813..10818,
                     10837..10839))
                     /gene="sspA"
                     /locus_tag="COSY_0009"
                     /note="substrate binding pocket (H-site) [chemical
                     binding]; other site"
                     /db_xref="CDD:198286"
     gene            complement(11193..11879)
                     /gene="petC"
                     /locus_tag="COSY_0010"
                     /db_xref="GeneID:5172046"
     CDS             complement(11193..11879)
                     /gene="petC"
                     /locus_tag="COSY_0010"
                     /EC_number="1.10.2.2"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol-cytochrome c reductase cytochrome c1
                     subunit"
                     /protein_id="YP_001218873.1"
                     /db_xref="GI:148244179"
                     /db_xref="GeneID:5172046"
                     /translation="MKNIVHTLLIAVTILIFSFNTFASGNEIHLDQANTNINDKKSLR
                     RGAKLFMNYCSGCHSIQFMRYNRIGKDLNIADAEIEKHFILGNEKIGETITSAMSVTD
                     ANQWFGQSPDLSLVSRSKGVDWIYSYLHGFYKDNSRIFGVNNHILKNVSMPDVLWKLK
                     QDKSSKKFDQDIRDITNFLDYVGEPAKLVRFNLGIKVLGFLLILFIFSYLLKIEYWKD
                     IKYGKWRTKH"
     misc_feature    complement(<11583..11879)
                     /gene="petC"
                     /locus_tag="COSY_0010"
                     /note="Cytochrome c; Region: Cytochrom_C; cl11414"
                     /db_xref="CDD:245607"
     misc_feature    complement(11223..11777)
                     /gene="petC"
                     /locus_tag="COSY_0010"
                     /note="Cytochrome C1 family; Region: Cytochrom_C1;
                     pfam02167"
                     /db_xref="CDD:216912"
     gene            complement(11884..13107)
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /db_xref="GeneID:5171851"
     CDS             complement(11884..13107)
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /EC_number="1.10.2.2"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol-cytochrome c reductase cytochrome b
                     subunit"
                     /protein_id="YP_001218874.1"
                     /db_xref="GI:148244180"
                     /db_xref="GeneID:5171851"
                     /translation="MNNNKNWIDQRFPLTKVWNEHLAEYYTPRNFNFWYFFGSLAMLV
                     LVIQIVTGIFLTMHFKPDAIHAFASVEYIMRDVNWGWLIRYLHSTGASAFFVVIYLHI
                     HRSLLYGSYKTPRELIWILGMVLYIALMAEAFMGYVLPWGQMSYWGAQVIISLFGSVP
                     IFGPEILTFILGDYAVGDPVLNRFFSLHVIALPLILAILVFLHIVALHTVGSNNPDGI
                     EIKKNKNKDGIPKDGVPFHPYYSVKDIVGVVVFLMIFSSIVFFAPAMNGYFLESSNFI
                     EANPLQTPNHIAPLWYLTPFYSVLRAIPPMFGSQFPGVVGMFASLLILIALPWLDRSK
                     VKSIRYRSWPYKIALGIFVISFIILGYLGMQPVTPINALLARVFTLTYFGFFILMPWF
                     TSIGKTKSLPIRVTE"
     misc_feature    complement(11938..13086)
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="cytochrome b; Provisional; Region: CYTB; MTH00145"
                     /db_xref="CDD:177203"
     misc_feature    complement(12550..13071)
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is
                     a subunit of cytochrome bc1, an 11-subunit mitochondrial
                     respiratory enzyme. Cytochrome b spans the mitochondrial
                     membrane with 8 transmembrane helices (A-H) in eukaryotes.
                     In plants and cyanobacteria; Region: Cytochrome_b_N;
                     cd00284"
                     /db_xref="CDD:238176"
     misc_feature    complement(order(12982..12984,12991..12993,13042..13047))
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="Qi binding site; other site"
                     /db_xref="CDD:238176"
     misc_feature    complement(order(12628..12630,12652..12657,12667..12687,
                     12697..12699,12727..12732,12739..12741,12748..12753,
                     12760..12765,12775..12792,12811..12813,12820..12825,
                     12829..12834,12838..12843,12850..12855,12862..12864,
                     12907..12909,12979..12981,12988..12993,13000..13005,
                     13021..13029,13039..13044))
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="intrachain domain interface; other site"
                     /db_xref="CDD:238176"
     misc_feature    complement(order(12766..12768,12850..12852,12859..12867,
                     12871..12885,12892..12897,12904..12909,12934..12939,
                     12946..12948,12958..12960,13021..13023,13030..13032,
                     13036..13041))
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="interchain domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238176"
     misc_feature    complement(order(12730..12735,12739..12744,12751..12756,
                     12796..12798,12802..12807,12814..12816,12826..12828,
                     12982..12987,12991..12996,13003..13005))
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="heme bH binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238176"
     misc_feature    complement(order(12688..12693,12697..12702,12709..12714,
                     12835..12837,12844..12849,12856..12858,12898..12900,
                     12931..12933,12940..12945,12949..12954,12961..12966,
                     12973..12975))
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="heme bL binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238176"
     misc_feature    complement(order(12556..12558,12640..12642,12652..12657,
                     12664..12666,12703..12708,12715..12720,12727..12729))
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="Qo binding site; other site"
                     /db_xref="CDD:238176"
     misc_feature    complement(order(12079..12084,12103..12108,12280..12285,
                     12292..12294,12319..12321,12325..12330,12337..12342,
                     12349..12351,12358..12363,12370..12372,12379..12384,
                     12388..12396,12403..12417))
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="interchain domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238179"
     misc_feature    complement(order(12115..12117,12121..12129,12133..12138,
                     12145..12147,12187..12189,12232..12243,12247..12249,
                     12256..12264,12268..12282,12286..12291,12295..12297,
                     12319..12321,12328..12336,12340..12345,12355..12357,
                     12364..12369,12376..12381,12388..12390,12400..12402,
                     12406..12414))
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="intrachain domain interface; other site"
                     /db_xref="CDD:238179"
     misc_feature    complement(order(12376..12378,12400..12402))
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="Qi binding site; other site"
                     /db_xref="CDD:238179"
     misc_feature    complement(11959..12279)
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="Cytochrome b(C-terminal)/b6/petD; Region:
                     Cytochrom_B_C; pfam00032"
                     /db_xref="CDD:200943"
     misc_feature    complement(order(12157..12159,12217..12222,12229..12231,
                     12238..12243,12247..12249))
                     /gene="petB"
                     /locus_tag="COSY_0011"
                     /note="Qo binding site; other site"
                     /db_xref="CDD:238179"
     gene            complement(13121..13717)
                     /gene="petA"
                     /locus_tag="COSY_0012"
                     /db_xref="GeneID:5171856"
     CDS             complement(13121..13717)
                     /gene="petA"
                     /locus_tag="COSY_0012"
                     /EC_number="1.10.2.2"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol-cytochrome c reductase iron-sulfur
                     subunit"
                     /protein_id="YP_001218875.1"
                     /db_xref="GI:148244181"
                     /db_xref="GeneID:5171856"
                     /translation="MSEQEIDLKKRRFLTSATSVVGAIGVGFVLVPFLSSWMPSARAK
                     AAGAPIDVDISKLDNGQLVRVLWRKKPVWIFKRDKKTIKNLMTLNSILTDPNSNEISQ
                     QPKYAQNLYRSINPDVAVIIGVCTHLGCSPTYRPELGASDLGGDSWKGGFYCPCHGSK
                     FDLAGRVYTGVPAPTNLVIPPYHFVADSLIRIGIDPKA"
     misc_feature    complement(13598..13717)
                     /gene="petA"
                     /locus_tag="COSY_0012"
                     /note="Ubiquitinol-cytochrome C reductase Fe-S subunit TAT
                     signal; Region: UCR_Fe-S_N; pfam10399"
                     /db_xref="CDD:150981"
     misc_feature    complement(13139..13693)
                     /gene="petA"
                     /locus_tag="COSY_0012"
                     /note="ubiquinol-cytochrome c reductase, iron-sulfur
                     subunit; Region: Rieske_proteo; TIGR01416"
                     /db_xref="CDD:233404"
     misc_feature    complement(13139..13573)
                     /gene="petA"
                     /locus_tag="COSY_0012"
                     /note="Iron-sulfur protein (ISP) component of the bc(1)
                     complex family, Rieske domain; The Rieske domain is a
                     [2Fe-2S] cluster binding domain involved in electron
                     transfer. The bc(1) complex is a multisubunit enzyme found
                     in many different organisms including...; Region:
                     Rieske_cytochrome_bc1; cd03470"
                     /db_xref="CDD:239552"
     misc_feature    complement(order(13241..13243,13247..13249,13256..13258,
                     13334..13339,13343..13345))
                     /gene="petA"
                     /locus_tag="COSY_0012"
                     /note="[2Fe-2S] cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239552"
     gene            complement(13826..14131)
                     /locus_tag="COSY_0013"
                     /db_xref="GeneID:5171861"
     CDS             complement(13826..14131)
                     /locus_tag="COSY_0013"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218876.1"
                     /db_xref="GI:148244182"
                     /db_xref="GeneID:5171861"
                     /translation="MCQYKTLTNLANFIPNGRLGQLFTKAKSYNRINIELNKILPNTL
                     KPFIKLCLIKDNTATLITNNHAIYFRAQKQIVKLLEILIQIPALESITHIEIKINVN"
     misc_feature    complement(<13829..14122)
                     /locus_tag="COSY_0013"
                     /note="Protein of unknown function (DUF721); Region:
                     DUF721; cl02324"
                     /db_xref="CDD:242985"
     gene            14184..16877
                     /gene="secA"
                     /locus_tag="COSY_0014"
                     /db_xref="GeneID:5172393"
     CDS             14184..16877
                     /gene="secA"
                     /locus_tag="COSY_0014"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase SecA subunit"
                     /protein_id="YP_001218877.1"
                     /db_xref="GI:148244183"
                     /db_xref="GeneID:5172393"
                     /translation="MSIINNILSKIVGSRNDRLIKVLYKTVNQITELESNMQALSDEQ
                     LKSKTQEFKDRLNKKETLNSILIEAFAVIREASIRVLDLRHHDVQLIGGIVLNNGNIA
                     EMGTGEGKTLVATLPAYLNALNGKGVHIVTVNDYLAFRDAQWMGKVFNFLSMSVGIIT
                     SNMSYENKQVAYLCDIVYATNNELGFDYLRDNMAFTSEQKVQRMLNFAIVDEVDSILI
                     DEARTPLIISGPTDDYAQIYQAINHMIPHFTKQIESGAGKEIVIEVAGDYTVDEKHKQ
                     VFLTDNGHGKAERLLIDAGALLEGVSLYDASNILLMQHINSALRAHILFQKNVDYIIQ
                     NDEVVIVDEFTGRTMLGRRWSEGLHQAIEAKERVSIKKENQTLASITFQNYFRLYRTL
                     SGMTGTADTEAVEFQDIYGLETVVVPPNKPSTRVDKSDLIYLTTQEKFKAIALEVANC
                     QKTGQPVLVGTSSIENSELISTLLEKNNIKHEVLNAKQHEREAIIIANAGSIGAVTIA
                     TNMAGRGTDIVLGGKLLEQATNKQKIDWQNRHDDVIKAGGLHIVGTERNESRRVDNQL
                     RGRSARQGDVGSTRFYLSLEDNLMRIFASEKMSSTMQKLGMKKGESIEHKMVNRAIEN
                     AQRKVEGMNYDARKHLLEYDDVANDQRKVIYQLRDDLMSVNDVQDRFISIREKVIKQL
                     FSDYISAELMEEDWNVEGFYNALKSDYSVDLPLQQWLNKGVDIDELQSRIIQGMSTIC
                     DYKEETVGTKPMREFEKAVMLKTIDHYWKEHLATMDYLRQSVNLRGYAQKNPMQEYKR
                     ESFAMFTSLLDTINIEIVKSLSNVTINENTDILDVEQQNNDDAQATHSNPNEQTKQAS
                     ITNNIQTQTDQQNTYQRKEKKVGRNEPCPCGSGKKYKKCHG"
     misc_feature    14193..16655
                     /gene="secA"
                     /locus_tag="COSY_0014"
                     /note="preprotein translocase subunit SecA; Reviewed;
                     Region: PRK12904"
                     /db_xref="CDD:237259"
     misc_feature    14463..>14834
                     /gene="secA"
                     /locus_tag="COSY_0014"
                     /note="DEAD/DEAH box helicase; Region: DEAD; pfam00270"
                     /db_xref="CDD:215832"
     misc_feature    order(14496..14504,14511..14516)
                     /gene="secA"
                     /locus_tag="COSY_0014"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238005"
     misc_feature    14814..14825
                     /gene="secA"
                     /locus_tag="COSY_0014"
                     /note="putative Mg++ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238005"
     misc_feature    14871..15272
                     /gene="secA"
                     /locus_tag="COSY_0014"
                     /note="SecA preprotein cross-linking domain; Region:
                     SecA_PP_bind; smart00958"
                     /db_xref="CDD:214938"
     misc_feature    16821..16874
                     /gene="secA"
                     /locus_tag="COSY_0014"
                     /note="SEC-C motif; Region: SEC-C; pfam02810"
                     /db_xref="CDD:202406"
     gene            17357..18385
                     /gene="pyrC"
                     /locus_tag="COSY_0015"
                     /db_xref="GeneID:5171812"
     CDS             17357..18385
                     /gene="pyrC"
                     /locus_tag="COSY_0015"
                     /EC_number="3.5.2.3"
                     /note="catalyzes the formation of N-carbamoyl-L-aspartate
                     from (S)-dihydroorotate in pyrimidine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="YP_001218878.1"
                     /db_xref="GI:148244184"
                     /db_xref="GeneID:5171812"
                     /translation="MQFKMIQPDDCHLHIRSGMALKSIIGMTVKQMGRAIIMPNLNPP
                     ITNVTQACAYKAEILSALPKGNRFNPLMTLYLTDNTTSKDIQEAIDHDVIAVKLYPAG
                     ATTNSDSGVTNIAKLYPTLESMQKLGMPLLVHGEVTRSEVDIFDREAVFIDEVLNQVV
                     SDFPELKIVFEHITTKNAVDFVLASHHKIAATVTPHHLLANRNDMLVNGIRPHYFCLP
                     VLKRRNPHQIALLDVVTSGNVKFFLGTDSAPHMKTDKESACGCAGIFNAHCAIELYVM
                     VFEHQNALDKLEGFASKFGADFYNLPYNKKIITLNKKDWTIPASYSFAHSNIVPFMAT
                     KTLSWKLV"
     misc_feature    17363..18373
                     /gene="pyrC"
                     /locus_tag="COSY_0015"
                     /note="Dihydroorotase (DHOase) catalyzes the reversible
                     interconversion of carbamoyl aspartate to dihydroorotate,
                     a key reaction in the pyrimidine biosynthesis. In contrast
                     to the large polyfunctional CAD proteins of higher
                     organisms, this group of DHOases is...; Region: DHOase;
                     cd01294"
                     /db_xref="CDD:238619"
     misc_feature    order(17390..17392,17396..17398,17645..17647,17756..17758,
                     17870..17872,18092..18094)
                     /gene="pyrC"
                     /locus_tag="COSY_0015"
                     /note="active site"
                     /db_xref="CDD:238619"
     misc_feature    order(17402..17404,18002..18007,18098..18100,18104..18106,
                     18140..18145)
                     /gene="pyrC"
                     /locus_tag="COSY_0015"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238619"
     misc_feature    order(17786..17797,17960..17965,17999..18001,18020..18022,
                     18128..18136)
                     /gene="pyrC"
                     /locus_tag="COSY_0015"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238619"
     gene            complement(18778..19680)
                     /gene="ribF"
                     /locus_tag="COSY_0016"
                     /db_xref="GeneID:5172693"
     CDS             complement(18778..19680)
                     /gene="ribF"
                     /locus_tag="COSY_0016"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /note="bifunctional riboflavin kinase / FMN
                     adenylyltransferase."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin biosynthesis protein
                     RibF"
                     /protein_id="YP_001218879.1"
                     /db_xref="GI:148244185"
                     /db_xref="GeneID:5172693"
                     /translation="MKIIRGLQNLKPHLGSVVTIGNFDGVHIGHQKIIKTLVNKAQIM
                     NLPSVIVSFSPTPQHFFGHAQATLSSFKQKHALLTSLGVDEHLLINFNASFSQLTANT
                     FIHEILLDKLKVKLCLVGDDFRFGSNQTGDFSLLQTFNFEVEKTPTVLYNLDRVSSSK
                     IRQSLKKGNFYLANQLLGRKFSISGKIIHCQKQGRTIGFPTINIPIKRKISPLLGIFA
                     VNVELNGKIYNGVCNLGKRPTVGGETILLEVFLFDFNKQVYGEYTKVIFKYKIRDEQK
                     FNSFLALKEQIKLDVKNAKFFFGL"
     misc_feature    complement(18781..19677)
                     /gene="ribF"
                     /locus_tag="COSY_0016"
                     /note="bifunctional riboflavin kinase/FMN
                     adenylyltransferase; Reviewed; Region: PRK05627"
                     /db_xref="CDD:235536"
     misc_feature    complement(19114..19635)
                     /gene="ribF"
                     /locus_tag="COSY_0016"
                     /note="FAD synthetase, N-terminal domain of the
                     bifunctional enzyme; Region: FAD_synthetase_N; cd02064"
                     /db_xref="CDD:185679"
     misc_feature    complement(order(19207..19215,19237..19239,19315..19317,
                     19591..19593,19600..19602,19609..19620))
                     /gene="ribF"
                     /locus_tag="COSY_0016"
                     /note="active site"
                     /db_xref="CDD:185679"
     misc_feature    complement(18787..19155)
                     /gene="ribF"
                     /locus_tag="COSY_0016"
                     /note="Riboflavin kinase; Region: Flavokinase; pfam01687"
                     /db_xref="CDD:190069"
     gene            complement(19999..21054)
                     /gene="metA"
                     /locus_tag="COSY_0017"
                     /db_xref="GeneID:5172532"
     CDS             complement(19999..21054)
                     /gene="metA"
                     /locus_tag="COSY_0017"
                     /EC_number="2.3.1.46"
                     /note="catalyzes the formation of O-succinyl-L-homoserine
                     from succinyl-CoA and L-homoserine in methionine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="YP_001218880.1"
                     /db_xref="GI:148244186"
                     /db_xref="GeneID:5172532"
                     /translation="MPLIAHSNLPSFSRLKDEGETILSKDRANNQTIRELHIGLLNTM
                     PDAALEATERQFFRLIGHSNQIAQFYLHPFTLPSIKRGKKANKHIKQHYQTFTDIKAQ
                     GLDALIITGAHIEQEDLQKAPFYEELKEVVDWSYDHVTSTLCSCLATHAVLEFRYGQK
                     RKAIGEKCWGVFPHQILDRQHPLMSGVNTRFNVPHSRFNEISKKQFNAAGVKILVESK
                     IGVHLGVSEDLLRIVFFQGHPEYDTISLLKEYKRDIISYLKKTRNNYPPFPEHYLTEQ
                     SKAILNEYKTKLLSSEFNISNFPEKLIKKTLDNTWGNATNVIINNWIGCVYQTTHEDI
                     EKPFMNGINPNDPLNLK"
     misc_feature    complement(20050..21054)
                     /gene="metA"
                     /locus_tag="COSY_0017"
                     /note="homoserine O-succinyltransferase; Provisional;
                     Region: PRK05368"
                     /db_xref="CDD:235433"
     misc_feature    complement(20407..20943)
                     /gene="metA"
                     /locus_tag="COSY_0017"
                     /note="Type 1 glutamine amidotransferase (GATase1)-like
                     domain found in homoserine trans-succinylase (HTS);
                     Region: GATase1_HTS; cd03131"
                     /db_xref="CDD:153225"
     misc_feature    complement(20914..20916)
                     /gene="metA"
                     /locus_tag="COSY_0017"
                     /note="proposed active site lysine [active]"
                     /db_xref="CDD:153225"
     misc_feature    complement(20617..20619)
                     /gene="metA"
                     /locus_tag="COSY_0017"
                     /note="conserved cys residue [active]"
                     /db_xref="CDD:153225"
     gene            complement(21054..21890)
                     /locus_tag="COSY_0018"
                     /db_xref="GeneID:5172183"
     CDS             complement(21054..21890)
                     /locus_tag="COSY_0018"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218881.1"
                     /db_xref="GI:148244187"
                     /db_xref="GeneID:5172183"
                     /translation="MKLSFSEFKNSNHKRLTLLGMSGVGKTHLAKLLSHQDKYFHYSS
                     DYRIGAKYLNDKILGNIKNHVKQDKWLKDLLDKESISIQNHITFDNLSSVSTFLGKTG
                     NPELGGTSIDTFIARQIMHLNAEIKTMLDVPQFIKKAKAQGFNHFINDAGGSLCELDN
                     EQVYQTLSDNTVILYIRASKTNEIALIKRAQTHPKPLYYQANFLKHELDIYLQENQLI
                     YIAQINPNKFVRWVFPRLLEHRKPKYEAIAKKYGYIIDNEDLYQCRSANEIFELIYRA
                     MN"
     misc_feature    complement(<21723..21833)
                     /locus_tag="COSY_0018"
                     /note="AAA domain; Region: AAA_17; cl17253"
                     /db_xref="CDD:247807"
     misc_feature    complement(<21285..21536)
                     /locus_tag="COSY_0018"
                     /note="Formate/glycerate dehydrogenases, D-specific
                     2-hydroxy acid dehydrogenases and related dehydrogenases;
                     Region: FDH_GDH_like; cl17240"
                     /db_xref="CDD:247794"
     gene            complement(21918..23105)
                     /locus_tag="COSY_0019"
                     /db_xref="GeneID:5172381"
     CDS             complement(21918..23105)
                     /locus_tag="COSY_0019"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="YP_001218882.1"
                     /db_xref="GI:148244188"
                     /db_xref="GeneID:5172381"
                     /translation="MNNDFPRIKRLPDYVFAVTNKLKAKARARGEDIIDFGMGNPDQP
                     TPNHIVEKLVEATRRKDTHRYATFRGIPRLRKAISNWYKNRFNVDINPETEAIVTIGS
                     KEGLYNLAQAIVDSGDTVLVPNPAYPIHPYGFVLAGAKIQYVPCGPDDDFLTELEHSI
                     KNTLSKPKMLVLNYPSNPTTQCAELYFFEKVIKIAKKHEIWVVQDLAYADIVFDGYVA
                     PSILQVEGAKKISVEFFSLSKSYNMPGWRVGFMVGNPTLVSALAKIKSYLDYGMFTPI
                     QIAAIEALEGDQSCVKEISNMYQDRRDVLCNGLDSIGWIVTPPKATMFVWAKIPEFYQ
                     HMGSLEFTKKLLKIAKISVSPGIGFGSYGDQYVRFGLIENEHRTRQAIRGIREMFKKD
                     GLL"
     misc_feature    complement(21921..23099)
                     /locus_tag="COSY_0019"
                     /note="aminotransferase; Validated; Region: PRK08175"
                     /db_xref="CDD:181268"
     misc_feature    complement(21945..23006)
                     /locus_tag="COSY_0019"
                     /note="Aspartate aminotransferase family. This family
                     belongs to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). Pyridoxal phosphate
                     combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine...; Region: AAT_like;
                     cd00609"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(22365..22367,22389..22394,22398..22400,
                     22482..22484,22575..22577,22725..22727,22797..22805))
                     /locus_tag="COSY_0019"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(22269..22271,22278..22280,22365..22373,
                     22503..22505,22695..22697,22794..22796))
                     /locus_tag="COSY_0019"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99734"
     misc_feature    complement(22389..22391)
                     /locus_tag="COSY_0019"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
     gene            complement(23136..23462)
                     /gene="fkpA"
                     /locus_tag="COSY_0020"
                     /db_xref="GeneID:5172384"
     CDS             complement(23136..23462)
                     /gene="fkpA"
                     /locus_tag="COSY_0020"
                     /EC_number="5.2.1.8"
                     /note="FkbP-type peptidyl-prolyl cis-trans isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="YP_001218883.1"
                     /db_xref="GI:148244189"
                     /db_xref="GeneID:5172384"
                     /translation="MEDLEIQNLKIGTGAACKAGDFISMHYTGWFIDGKKFDSSVDRN
                     ETFNFKLGVGQVILGWDQGINGMCIGGKRKLIIPSKLAYGEMGSGNLIPSNTTLIFEV
                     ELLAIQ"
     misc_feature    complement(23142..>23462)
                     /gene="fkpA"
                     /locus_tag="COSY_0020"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerases 1
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: FkpA; COG0545"
                     /db_xref="CDD:223619"
     misc_feature    complement(23148..23411)
                     /gene="fkpA"
                     /locus_tag="COSY_0020"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase;
                     Region: FKBP_C; pfam00254"
                     /db_xref="CDD:215821"
     gene            complement(23474..24274)
                     /locus_tag="COSY_0021"
                     /db_xref="GeneID:5171946"
     CDS             complement(23474..24274)
                     /locus_tag="COSY_0021"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218884.1"
                     /db_xref="GI:148244190"
                     /db_xref="GeneID:5171946"
                     /translation="MQINGLIKKMHTYLNSNIVQYQLPIGNKLLNMNDLVGEQISLQF
                     NGEIVCSNCKKHINKIYSQGFCYSCCQSLARCDLCIIKPETCHYHLGTCREPEWGLDN
                     CFNPHVVYLANSSGIKVGITRKSNIPSRWIDQGAIVALAILEIDNRLKSGKIEVALKN
                     YVNDKTNWRKMLKNEIEQTNIKKTNNDLLKKIPHLISDLSAIVLDNEVLTINYPVIKY
                     PNKISSLNFEKTPKIKGILQGIKGQYLLLNTGVLNIRKFSSHHITIIY"
     misc_feature    complement(23486..24166)
                     /locus_tag="COSY_0021"
                     /note="Protein of unknown function (DUF2797); Region:
                     DUF2797; pfam10977"
                     /db_xref="CDD:220920"
     gene            complement(24280..25155)
                     /gene="purC"
                     /locus_tag="COSY_0022"
                     /db_xref="GeneID:5172379"
     CDS             complement(24280..25155)
                     /gene="purC"
                     /locus_tag="COSY_0022"
                     /EC_number="6.3.2.6"
                     /note="catalyzes the formation of
                     (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-
                     carboxamido)succinate from
                     5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and
                     L-aspartate in purine biosynthesis; SAICAR synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole-succinocarboxamide
                     synthase"
                     /protein_id="YP_001218885.1"
                     /db_xref="GI:148244191"
                     /db_xref="GeneID:5172379"
                     /translation="MILSSTNLSLPLIQKGKVRDIYDIDDKRMLIVTTDRLSVFDVIF
                     DEPINNKGLILTKMANFWFEKTRHIIKNHLTLEPLDSILNNEEADLIKGRGIIVKKLK
                     PIAIEAIVRGYIIGSSWKDYQTLGKICSIKLPKGLRLAEKLSSALYTPSNKATMNQHD
                     KNIDFTQTVKIVGKRLAQQIKQVSLEIYNFAGNYALERGIIIADTKFEFGLDENNQLT
                     LMDEVLTPDSSRFWSKIDYQIGNSPKSFDKQIIRDYLETLNWDKTISVPTLPKSIIQQ
                     TADKYKEVQQRLMQH"
     misc_feature    complement(24292..25122)
                     /gene="purC"
                     /locus_tag="COSY_0022"
                     /note="phosphoribosylaminoimidazole-succinocarboxamide
                     synthase; Reviewed; Region: PRK09362"
                     /db_xref="CDD:181800"
     misc_feature    complement(24292..25122)
                     /gene="purC"
                     /locus_tag="COSY_0022"
                     /note="non-metazoan
                     5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide
                     (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414"
                     /db_xref="CDD:133469"
     misc_feature    complement(order(24493..24498,24532..24534,24697..24699,
                     24847..24849,24853..24855,24859..24861,24937..24939,
                     25063..25065,25069..25071,25090..25095,25099..25101,
                     25105..25110,25114..25119))
                     /gene="purC"
                     /locus_tag="COSY_0022"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:133469"
     misc_feature    complement(order(24466..24477,24493..24495,24532..24534,
                     24538..24546,24676..24678,24697..24699,24703..24705,
                     24805..24813,24823..24825,24829..24831,24835..24837,
                     24847..24849,24853..24864,24934..24936,25033..25035,
                     25069..25071,25093..25095,25099..25110,25114..25116))
                     /gene="purC"
                     /locus_tag="COSY_0022"
                     /note="active site"
                     /db_xref="CDD:133469"
     misc_feature    complement(order(24466..24477,24538..24546,24676..24678,
                     24703..24705,24805..24813,24823..24825,24829..24831,
                     24835..24837,25033..25035))
                     /gene="purC"
                     /locus_tag="COSY_0022"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:133469"
     gene            25265..25882
                     /locus_tag="COSY_0023"
                     /db_xref="GeneID:5172344"
     CDS             25265..25882
                     /locus_tag="COSY_0023"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218886.1"
                     /db_xref="GI:148244192"
                     /db_xref="GeneID:5172344"
                     /translation="MLIKILIICVLIQHSAIASTLSKNALRLIKIGHEIGSRDVTLRG
                     QYFLLKSAFDLGDFDAMYEVSKQIRYGSKLMGYVPLERAANEILIKLVRKSYDPALYE
                     YALNLLDGSDGFIKNEFLALHLFEESFKVHGNAKSALMAAIICNESLVPGTKELNYIN
                     ELITFAILNNVAGAQAYQNQYIRLDYLSDLNPPSWRIWVDTQVLN"
     gene            complement(25842..27014)
                     /locus_tag="COSY_0024"
                     /db_xref="GeneID:5172378"
     CDS             complement(25842..27014)
                     /locus_tag="COSY_0024"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218887.1"
                     /db_xref="GI:148244193"
                     /db_xref="GeneID:5172378"
                     /translation="MKLSNSMGRFYKITLLILMFFSMILTPAYSDNNTYHFTIKHGDS
                     LSQYFSKLGLSNRLLINLLIANKHNKKLNQLNIGHKLIIRLHKNQHFKSLTYQLNNII
                     NLDIVLNGNYFSTVLNKQPKKTLSNSSTTVVNINHSFGVDAQKAGISFSTINSVIKAL
                     SWQLNLHTDLKKGDRFIIVSNGSIKPAAIIYQSIINNKSIEAFAYKNKHGHTSYFDRF
                     GHSLSSSFLRAPLKYKRISSKFQLKRYHPILKTWRPHRAVDYAAKHGTPVYSTANGII
                     TTKGRKGSLGKVIIIEHDFDYTTVYAHLSKYANNLYKDKKIKKGQIIGYVGSTGHSTG
                     PHLHYELHHKGKRRNPITYKVPPQKNIDHINIKKFKTKINKILSNLKLEYQPKYAN"
     misc_feature    complement(25947..>26927)
                     /locus_tag="COSY_0024"
                     /note="putative peptidase; Provisional; Region: PRK11649"
                     /db_xref="CDD:236946"
     misc_feature    complement(25965..26258)
                     /locus_tag="COSY_0024"
                     /note="Peptidase family M23; Region: Peptidase_M23;
                     pfam01551"
                     /db_xref="CDD:216566"
     gene            complement(26989..28140)
                     /gene="dxr"
                     /locus_tag="COSY_0025"
                     /db_xref="GeneID:5172392"
     CDS             complement(26989..28140)
                     /gene="dxr"
                     /locus_tag="COSY_0025"
                     /EC_number="1.1.1.267"
                     /note="catalyzes the NADP-dependent rearrangement and
                     reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to
                     2-C-methyl-D-erythritol 4-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose 5-phosphate reductoisomerase"
                     /protein_id="YP_001218888.1"
                     /db_xref="GI:148244194"
                     /db_xref="GeneID:5172392"
                     /translation="MKNITLLGATGSIGKSTLSVVDLHPDKFNIFALSANTNWKQMIK
                     LCNKYQPSYAIMVDEQSAEKLSNAITTDIQVLSSVQALDKIVTHQDTDYVMAAIVGAI
                     GMSSALCGAKAGKRIMLANKESLVLAGDIFMKTVKEFNAELIPVDSEHSAIFQCLKSG
                     KSGLNKIQLTASGGPFLHTPISQFKSITPDEACAHPNWSMGRKISVDSATMMNKGLEV
                     IEAHYLFSLTPKQIDVVIHPQSIVHSSVFYKDGSTLSQLGNPDMRTVIAYAMSYPKRM
                     NSGVSELDLTSTASLEFYQPDFEKFTCLKLAFEALNKGGNAMITMNAANEIAVKYFLN
                     HQISFLDIPKIIDQTLSTMKHTTLNSLEEVINNDLIAREIAHEIIKQYG"
     misc_feature    complement(26992..28140)
                     /gene="dxr"
                     /locus_tag="COSY_0025"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase;
                     Provisional; Region: PRK05447"
                     /db_xref="CDD:235472"
     misc_feature    complement(27754..28131)
                     /gene="dxr"
                     /locus_tag="COSY_0025"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase;
                     Region: DXP_reductoisom; pfam02670"
                     /db_xref="CDD:217176"
     misc_feature    complement(27466..27714)
                     /gene="dxr"
                     /locus_tag="COSY_0025"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase
                     C-terminal; Region: DXP_redisom_C; pfam08436"
                     /db_xref="CDD:203943"
     misc_feature    complement(27016..27369)
                     /gene="dxr"
                     /locus_tag="COSY_0025"
                     /note="DXP reductoisomerase C-terminal domain; Region:
                     DXPR_C; pfam13288"
                     /db_xref="CDD:222027"
     gene            complement(28137..28937)
                     /gene="cdsA"
                     /locus_tag="COSY_0026"
                     /db_xref="GeneID:5172438"
     CDS             complement(28137..28937)
                     /gene="cdsA"
                     /locus_tag="COSY_0026"
                     /EC_number="2.7.7.41"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="YP_001218889.1"
                     /db_xref="GI:148244195"
                     /db_xref="GeneID:5172438"
                     /translation="MLTKRIITAFILAPLIIWAIFAMPNYYFEQLLLIFTALGAWEFS
                     RLIKFRRLIARILLVFSIVICALIIQKNTQIIPFILYLSVLWWTINLYWVLSYPSKTN
                     FWFDPLIVRIITGVLLLVPMWIALITLKQQYGSEYFLLLMLITWGADSGAYFIGKAIG
                     KWKLAPKLSSGKSIEGVIGGIVVALVVMMIFLQNQNIATNQYLDYLLLTVVIANISVL
                     GDLFESLFKRISNIKDSGQILPGHGGILDRIDSLTATAPFFLLGLSLI"
     misc_feature    complement(28155..28937)
                     /gene="cdsA"
                     /locus_tag="COSY_0026"
                     /note="CDP-diglyceride synthetase [Lipid metabolism];
                     Region: CdsA; COG0575"
                     /db_xref="CDD:223648"
     misc_feature    complement(28161..28937)
                     /gene="cdsA"
                     /locus_tag="COSY_0026"
                     /note="CDP-diglyceride synthase; Provisional; Region:
                     cdsA; PRK11624"
                     /db_xref="CDD:183240"
     gene            complement(28948..29649)
                     /gene="uppS"
                     /locus_tag="COSY_0027"
                     /db_xref="GeneID:5172093"
     CDS             complement(28948..29649)
                     /gene="uppS"
                     /locus_tag="COSY_0027"
                     /EC_number="2.5.1.31"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl diphosphate synthase"
                     /protein_id="YP_001218890.1"
                     /db_xref="GI:148244196"
                     /db_xref="GeneID:5172093"
                     /translation="MSTLKHIAIIMDGNGRWASKRSLPRILGHQQGIQAVRNVVKACS
                     IRSIKTLTLFAFSSENKNRSTKEVSLLFKLFLDMLQQEVKKLNKHNIKLKIIGDMSLF
                     PIKIQQVAIDTQAILASNTGLTLIIAANYGGQWDITQAAIKAAKVAVAGDIKANDINV
                     KNFSQYLSLANEPNVDLLIRTSGELRISNFLLWDIAYSEFYFTKTLWPDFNKSELEKA
                     INSFNNRNRRFGTRL"
     misc_feature    complement(28960..29640)
                     /gene="uppS"
                     /locus_tag="COSY_0027"
                     /note="Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS);
                     homodimers which catalyze the successive 1&apos;-4
                     condensation of the isopentenyl diphosphate (IPP) molecule
                     to trans,trans-farnesyl diphosphate (FPP) or to
                     cis,trans-FPP to form long-chain polyprenyl...; Region:
                     CIS_IPPS; cl00230"
                     /db_xref="CDD:241707"
     misc_feature    complement(28960..29622)
                     /gene="uppS"
                     /locus_tag="COSY_0027"
                     /note="Putative undecaprenyl diphosphate synthase; Region:
                     Prenyltransf; pfam01255"
                     /db_xref="CDD:216392"
     misc_feature    complement(29614..29616)
                     /gene="uppS"
                     /locus_tag="COSY_0027"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238265"
     misc_feature    complement(29602..29613)
                     /gene="uppS"
                     /locus_tag="COSY_0027"
                     /note="putative FPP diphosphate  binding site; other site"
                     /db_xref="CDD:238265"
     misc_feature    complement(order(29269..29271,29275..29277,29320..29322,
                     29341..29343,29422..29430,29434..29439,29479..29493))
                     /gene="uppS"
                     /locus_tag="COSY_0027"
                     /note="putative FPP binding hydrophobic cleft; other site"
                     /db_xref="CDD:238265"
     misc_feature    complement(order(29050..29052,29062..29064,29071..29073,
                     29083..29085,29092..29097,29176..29178,29203..29205,
                     29212..29214,29224..29226,29248..29250))
                     /gene="uppS"
                     /locus_tag="COSY_0027"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238265"
     misc_feature    complement(order(29092..29094,29110..29112))
                     /gene="uppS"
                     /locus_tag="COSY_0027"
                     /note="putative IPP diphosphate binding site; other site"
                     /db_xref="CDD:238265"
     gene            29735..30502
                     /gene="hisF"
                     /locus_tag="COSY_0028"
                     /db_xref="GeneID:5171837"
     CDS             29735..30502
                     /gene="hisF"
                     /locus_tag="COSY_0028"
                     /note="catalyzes the conversion of
                     5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-
                     1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine
                     to imidazole-glycerol phosphate,
                     5-aminoimidazol-4-carboxamideribonucleotide and glutamate;
                     the HisF subunit acts as a cyclase"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="YP_001218891.1"
                     /db_xref="GI:148244197"
                     /db_xref="GeneID:5171837"
                     /translation="MSLAIRIIPCLDVCDGRVVKGTKFIDIKDAGDPVEVAKRYDLEG
                     ADEIIFLDITASIDGRDTMIHMVEAIAEQVFIPLTVGGGIRKAADVRAILNAGADKIT
                     INSAAIFNPNLINQLSKEFGSQCIVIAIDAKKIDYNKWGIFTHGGRKYTGIDAIEWAK
                     KMTCGDNGAGEVLLTSMDCDGVKTGFDLLLTRAVSDAVDVPVIASGGVGNLEHLSEGV
                     LQGAADAVLAASIFHFGEYTIQQAKKAMQENGIKVRL"
     misc_feature    29747..30481
                     /gene="hisF"
                     /locus_tag="COSY_0028"
                     /note="The cyclase subunit of imidazoleglycerol phosphate
                     synthase (HisF). Imidazole glycerol phosphate synthase
                     (IGPS) catalyzes the fifth step of histidine biosynthesis,
                     the formation of the imidazole ring. IGPS converts
                     N1-(5&apos;-phosphoribulosyl)...; Region: HisF; cd04731"
                     /db_xref="CDD:240082"
     misc_feature    29750..30448
                     /gene="hisF"
                     /locus_tag="COSY_0028"
                     /note="Histidine biosynthesis protein; Region:
                     His_biosynth; pfam00977"
                     /db_xref="CDD:216225"
     misc_feature    order(29792..29794,29885..29887,29981..29983,30044..30049,
                     30119..30121,30125..30127,30170..30172,30257..30259,
                     30272..30277,30347..30355,30419..30424)
                     /gene="hisF"
                     /locus_tag="COSY_0028"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240082"
     misc_feature    order(29855..29857,29870..29872,29936..29938,29948..29950,
                     29957..29959,29963..29965,30020..30022,30029..30034,
                     30104..30106,30245..30247,30329..30331,30404..30406)
                     /gene="hisF"
                     /locus_tag="COSY_0028"
                     /note="glutamase interaction surface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:240082"
     gene            30571..31107
                     /locus_tag="COSY_0029"
                     /db_xref="GeneID:5172631"
     CDS             30571..31107
                     /locus_tag="COSY_0029"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218892.1"
                     /db_xref="GI:148244198"
                     /db_xref="GeneID:5172631"
                     /translation="MNSKKELWILLASFVLPIAFGTAFFYLSPDSFTRHTINFGEFVN
                     PIIATEKEDVVFTDINHNLQGLWTLAYVTKQCDSICVKALHDIRTVRILMNEDMLRIQ
                     CLLLMTNKAKAKVQPADILVGYSIESLSRQFNQFPKNSLFLIDPLGNVMLRYDSKQLE
                     VKRVIKDLKRLLKYSRIG"
     gene            31120..32013
                     /gene="cyoE"
                     /locus_tag="COSY_0030"
                     /db_xref="GeneID:5172148"
     CDS             31120..32013
                     /gene="cyoE"
                     /locus_tag="COSY_0030"
                     /EC_number="2.5.1.-"
                     /note="converts protoheme IX and farnesyl diphosphate to
                     heme O"
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="YP_001218893.1"
                     /db_xref="GI:148244199"
                     /db_xref="GeneID:5172148"
                     /translation="MPLISDLLALCKLKVVALILFTAVVGMFLAVPAPYLPNGLLVLS
                     ASIGISMVAASAAVFNHVVDEQIDAQMSRTNQRPLPQGRVSKNQALVWGVFLGFIGLG
                     ILQLFVNIITVVLTFISLIGYTIVYTLYLKRATPQNIVIGGAAGATPPVLGWTAVSGT
                     QGIEYACLLFLIVFIWTPPHFWALAIYRVEEYKKIDMPMLPVTHGLAYTRTQILLYTV
                     LLLLVSLLPYLSGMSGLIYLVITIALGVRFLVYAIKIYNNPDDKMVAWSTFMYSINYL
                     MLLFIALLFDHYWLISPWEIL"
     misc_feature    31180..32001
                     /gene="cyoE"
                     /locus_tag="COSY_0030"
                     /note="protoheme IX farnesyltransferase; Provisional;
                     Region: PRK04375"
                     /db_xref="CDD:235293"
     misc_feature    31180..31956
                     /gene="cyoE"
                     /locus_tag="COSY_0030"
                     /note="UbiA prenyltransferase family; Region: UbiA;
                     pfam01040"
                     /db_xref="CDD:216260"
     gene            32014..32205
                     /locus_tag="COSY_0031"
                     /db_xref="GeneID:5172156"
     CDS             32014..32205
                     /locus_tag="COSY_0031"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218894.1"
                     /db_xref="GI:148244200"
                     /db_xref="GeneID:5172156"
                     /translation="MKRLGQVFKAVVSAMIGVGKKEDLVKDFARTEKQGPWPYIIIGL
                     IMTFIFIGLIIAVVKLVLP"
     misc_feature    32023..32199
                     /locus_tag="COSY_0031"
                     /note="Protein of unknown function (DUF2970); Region:
                     DUF2970; pfam11174"
                     /db_xref="CDD:204604"
     gene            complement(32314..33288)
                     /locus_tag="COSY_0032"
                     /db_xref="GeneID:5172341"
     CDS             complement(32314..33288)
                     /locus_tag="COSY_0032"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase assembly protein"
                     /protein_id="YP_001218895.1"
                     /db_xref="GI:148244201"
                     /db_xref="GeneID:5172341"
                     /translation="MFRKILQISIILALIVVILGAYTRLGNAGLGCPDWPGCYGQLSV
                     PDAKDGTTIQGFSRPLNIVKGWKEMLHRYVASTLGLTILILFFLALKGKLQHQQSLKL
                     PGFSAFFVMLQGAFGMWTVTFLVHPGIVTLHLIGGFLTTILLVWMFLNQKKTPTTYQN
                     VLKEHKFVLLITLTILSLQIILGGWTSANYAALSCGEYFPTCLNKWWPDLDFTHALYW
                     GSLGANYEYGILENPARSAIQVLHRIGALITTIFMLLLIYLFRNYNHLRFNLILSVIL
                     LTIQITLGVLNVVLSLPIIIAVLHNTIALLLLLSIITMVHKTFIKHNN"
     misc_feature    complement(32377..33231)
                     /locus_tag="COSY_0032"
                     /note="Cytochrome oxidase assembly protein; Region:
                     COX15-CtaA; pfam02628"
                     /db_xref="CDD:217153"
     misc_feature    complement(32377..33231)
                     /locus_tag="COSY_0032"
                     /note="Uncharacterized protein required for cytochrome
                     oxidase assembly [Posttranslational modification, protein
                     turnover, chaperones]; Region: CtaA; COG1612"
                     /db_xref="CDD:224528"
     gene            complement(33389..34216)
                     /locus_tag="COSY_0033"
                     /db_xref="GeneID:5172201"
     CDS             complement(33389..34216)
                     /locus_tag="COSY_0033"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218896.1"
                     /db_xref="GI:148244202"
                     /db_xref="GeneID:5172201"
                     /translation="MLQIPRMTKSINKKVYIKKISYSAPFTWLKKGVEDFTKCPALAL
                     FYGTLFTSFTYFYWDFLSHSPTLSDIAAPLLAMVVIIFGPISAMAMYDASKRLSIGEE
                     LSFRSILTVIKSAFKANGGSYPSFFLSIILIIIAIMWMVFTPLIYAILNTDTFVNQNQ
                     TIIEAILDDIINFNNPLFLVIYGIFTTVTAWISFMISWFSFPMVLDQNIDPFTAAHTS
                     IKTALANKIVMLIWVPIVGIIVLASLLTPYFLGMVVTVPVLAHATWHAYKSLISKLE"
     misc_feature    complement(33404..34168)
                     /locus_tag="COSY_0033"
                     /note="Predicted integral membrane protein (DUF2189);
                     Region: DUF2189; cl02291"
                     /db_xref="CDD:242969"
     gene            34428..35537
                     /gene="coxB"
                     /locus_tag="COSY_0034"
                     /db_xref="GeneID:5172562"
     CDS             34428..35537
                     /gene="coxB"
                     /locus_tag="COSY_0034"
                     /EC_number="1.9.3.1"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase subunit II"
                     /protein_id="YP_001218897.1"
                     /db_xref="GI:148244203"
                     /db_xref="GeneID:5172562"
                     /translation="MSKLTSYLGGLIAIVSVNAFSEYDLNMTRGVTSVSRDIYGLHMM
                     VFWVCVAIAIIVFSIMIYSLIVHRKSQGAVAANFHESTKAELLWTGIPIIILVLMAIP
                     ASSTLIDLEDTSKAQMTIKITGHQWKWQYDYPKEGISFISNLKQNSKDAIYSKNKHEN
                     YLLEVDNNLVLPVDTSIRFLITSNDVIHNWWVPDFGVKQDANPGFINDAWAKIDEIGT
                     YRGQCAELCGKDHGFMPIVVDVVSKADYAQWVLKKQITKAAKLTQSRKTWSEKDLTSL
                     GKKVYNTNCSSCHGITGKGIPGIFPALRGSSVATGDIKNHIGIVLHGKAGTAMASYKN
                     ILGDADIAAVITFERNSFGNQMGDLVQPSDIKSAR"
     misc_feature    34458..35225
                     /gene="coxB"
                     /locus_tag="COSY_0034"
                     /note="Heme/copper-type cytochrome/quinol oxidases,
                     subunit 2 [Energy production and conversion]; Region:
                     CyoA; COG1622"
                     /db_xref="CDD:224537"
     misc_feature    34494..34733
                     /gene="coxB"
                     /locus_tag="COSY_0034"
                     /note="Cytochrome C oxidase subunit II, transmembrane
                     domain; Region: COX2_TM; pfam02790"
                     /db_xref="CDD:202397"
     misc_feature    34779..35150
                     /gene="coxB"
                     /locus_tag="COSY_0034"
                     /note="Cytochrome C oxidase subunit II, periplasmic
                     domain; Region: COX2; pfam00116"
                     /db_xref="CDD:201014"
     misc_feature    35127..>35303
                     /gene="coxB"
                     /locus_tag="COSY_0034"
                     /note="cytochrome c-550; Provisional; Region: psbV;
                     cl17239"
                     /db_xref="CDD:247793"
     misc_feature    <35229..35534
                     /gene="coxB"
                     /locus_tag="COSY_0034"
                     /note="Cytochrome c, mono- and diheme variants [Energy
                     production and conversion]; Region: CccA; COG2010"
                     /db_xref="CDD:224921"
     misc_feature    35256..35468
                     /gene="coxB"
                     /locus_tag="COSY_0034"
                     /note="Cytochrome c; Region: Cytochrom_C; pfam00034"
                     /db_xref="CDD:215669"
     gene            35563..37164
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /db_xref="GeneID:5172144"
     CDS             35563..37164
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /EC_number="1.9.3.1"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase subunit I"
                     /protein_id="YP_001218898.1"
                     /db_xref="GI:148244204"
                     /db_xref="GeneID:5172144"
                     /translation="MTTITAYTSHHSPEKGLMRWIKTTNHKDIGSLYLWFAFIMLLVG
                     GVMAMVIRMELFQPGMQLINPQFFNQMTTMHGLIMVFGAIMPAFVGLGNWLIPMMIGA
                     PDMALPRMNNWSFWILPFAGGILLSTFFMEGGAPAFGWTFYAPLSTTFAPDSTDFFIF
                     AVHLLGFSSIMGAINIVATVVNMRALEMKLMDMPLFVWTWLITSFLLIGAMPVLAGAV
                     TMMLTDRNFGTAFFDAAGGGDPVMFQHIFWFFGHPEVYIMILPAFGVISHVIPTFARK
                     PLFGYSSMVYATASIAFLSYIVWAHHMFLTGMPVAGELYFMYATMLIAVPTGVKVFNW
                     ISTMWRGSMTFETPMLWAISFVFLFTIGGFSGVMVGIAPADIQYHDTYFVVAHFHYVL
                     VTGALWSIIAATFYWLPKWTGKMYNETLAQVHFWWAVVSVNVLFFPQHFLGLAGMPRR
                     IPDYSLQFADFNMISSIGGFAFGTSFILFTYIVIDCIRNGKPADARPWEGAKGLEWTL
                     EPKAQYHSFNKPPTRELIKQESQNS"
     misc_feature    35605..37131
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Heme/copper-type cytochrome/quinol oxidases,
                     subunit 1 [Energy production and conversion]; Region:
                     CyoB; COG0843"
                     /db_xref="CDD:223913"
     misc_feature    35632..37086
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Cytochrome C oxidase subunit I.  Cytochrome c
                     oxidase (CcO), the terminal oxidase in the respiratory
                     chains of eukaryotes and most bacteria, is a multi-chain
                     transmembrane protein located in the inner membrane of
                     mitochondria and the cell membrane of...; Region:
                     Cyt_c_Oxidase_I; cd01663"
                     /db_xref="CDD:238833"
     misc_feature    order(35632..35634,35869..35871,35881..35883,35887..35889,
                     35908..35910,36028..36030,36040..36042,36094..36096,
                     36106..36108,36166..36168,36187..36189,36196..36198,
                     36220..36222,36247..36255,36268..36273,36277..36279,
                     36307..36309,36418..36420,36427..36429,36436..36441,
                     36451..36453)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/III interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238833"
     misc_feature    order(35659..35661,35839..35841,35872..35874,35893..35895,
                     35902..35904,36064..36069,36085..36087,36097..36099)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="D-pathway; other site"
                     /db_xref="CDD:238833"
     misc_feature    order(35677..35679,35689..35691,35698..35700,35710..35712,
                     35947..35952,36793..36795,37012..37014,37021..37023)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/VIIc interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238833"
     misc_feature    order(35719..35721,35728..35733,36817..36819,36826..36831,
                     36928..36930,36982..36984)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/IV interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238833"
     misc_feature    order(35767..35769,36277..36279,36388..36390,36397..36402,
                     36475..36483,36490..36492,36499..36501,36523..36525,
                     36547..36549,36556..36558,36577..36585,36619..36621,
                     36673..36678,36682..36684,36688..36702,36892..36897,
                     36907..36915,36940..36945)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/II interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238833"
     misc_feature    order(35785..35787,36727..36729,36739..36741,36865..36867,
                     36976..36978)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Low-spin heme (heme a) binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238833"
     misc_feature    order(35941..35943,35950..35952)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/VIIa interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238833"
     misc_feature    order(36007..36009,36235..36246)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/VIa interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238833"
     misc_feature    order(36166..36168,36187..36189,36307..36309,36418..36420,
                     36427..36429,36436..36441,36451..36453)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Dimer interface; other site"
                     /db_xref="CDD:238833"
     misc_feature    order(36277..36279,36292..36297,36685..36687,36697..36702,
                     36907..36909)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Putative water exit pathway; other site"
                     /db_xref="CDD:238833"
     misc_feature    order(36316..36318,36463..36468,36721..36723)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Binuclear center (heme a3/CuB) [ion binding]; other
                     site"
                     /db_xref="CDD:238833"
     misc_feature    order(36316..36318,36328..36330,36361..36363,36463..36468,
                     36541..36543,36550..36552)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="K-pathway; other site"
                     /db_xref="CDD:238833"
     misc_feature    order(36391..36393,36403..36405,37081..37083)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/Vb interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238833"
     misc_feature    order(36466..36468,36697..36702,36907..36912)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Putative proton exit pathway; other site"
                     /db_xref="CDD:238833"
     misc_feature    36481..36483
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/VIb interface; other site"
                     /db_xref="CDD:238833"
     misc_feature    36580..36582
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/VIc interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238833"
     misc_feature    order(36724..36726,36907..36912)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Electron transfer pathway; other site"
                     /db_xref="CDD:238833"
     misc_feature    order(36820..36822,36991..36993)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/VIIIb interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238833"
     misc_feature    order(36928..36930,36940..36942)
                     /gene="coxA"
                     /locus_tag="COSY_0035"
                     /note="Subunit I/VIIb interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238833"
     gene            37255..37788
                     /locus_tag="COSY_0036"
                     /db_xref="GeneID:5172142"
     CDS             37255..37788
                     /locus_tag="COSY_0036"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase assembly protein"
                     /protein_id="YP_001218899.1"
                     /db_xref="GI:148244205"
                     /db_xref="GeneID:5172142"
                     /translation="MVDISVRKKITKTFWIKLILSPILMFAFAYAMVPIYDVFCEITG
                     FNGTTGRINSEQIYAIDESRRIEVSFFAMTMGGFPVQFRPKINSMEVIPGKFYTTSYI
                     AKNNTDKVVIGQAIPSVAPTEAALYFKKLECFCFNKQVFEPHQKIEMTLRFVIEPELD
                     KRIKDVSLSYNFFKIKS"
     misc_feature    37300..37782
                     /locus_tag="COSY_0036"
                     /note="cytochrome C oxidase assembly protein; Provisional;
                     Region: PRK05089"
                     /db_xref="CDD:235341"
     gene            37806..38690
                     /gene="coxC"
                     /locus_tag="COSY_0037"
                     /db_xref="GeneID:5172124"
     CDS             37806..38690
                     /gene="coxC"
                     /locus_tag="COSY_0037"
                     /EC_number="1.9.3.1"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase subunit III"
                     /protein_id="YP_001218900.1"
                     /db_xref="GI:148244206"
                     /db_xref="GeneID:5172124"
                     /translation="MNEQEYYVPSGTYWPIIGSIGVATLFVGFANQMHGASWGASIMA
                     LGFSILVFMMFGWFGQVVNESTSGMYNSQVDRSFRWGMSWFIFSEVMFFAAFFGVLFY
                     ARQLSVPWLGGSGNNFFTPDLWNGFSSTWKQIAFSTPGLILQSGTAISVPRQLVDAWG
                     LPALNTALLLLSGVTLTFAHHTLRNGDRNKIIGWLVATIVLGVLFLGFQITEYGHAYH
                     DGLKLTSGIYGSTFYMLTGFHGFHVTVGVIMLTVILYRVQKGHFSADNHFGFEGVAWY
                     WHFVDVVWLGLFIFVYWL"
     misc_feature    37851..38684
                     /gene="coxC"
                     /locus_tag="COSY_0037"
                     /note="Cytochrome c oxidase subunit III.  Cytochrome c
                     oxidase (CcO), the terminal oxidase in the respiratory
                     chains of eukaryotes and most bacteria, is a multi-chain
                     transmembrane protein located in the inner membrane of
                     mitochondria and the cell membrane of...; Region:
                     Cyt_c_Oxidase_III; cd01665"
                     /db_xref="CDD:238834"
     misc_feature    order(37971..37973,37980..37985,37992..37994,38001..38006)
                     /gene="coxC"
                     /locus_tag="COSY_0037"
                     /note="Subunit III/VIIa interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238834"
     misc_feature    order(37974..37979,37986..37991,37998..38000,38013..38015,
                     38046..38051,38058..38060,38550..38552,38571..38573,
                     38607..38612)
                     /gene="coxC"
                     /locus_tag="COSY_0037"
                     /note="Phospholipid binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238834"
     misc_feature    order(38022..38024,38031..38036,38067..38069,38076..38078,
                     38088..38093,38109..38111,38481..38486,38493..38495,
                     38505..38507)
                     /gene="coxC"
                     /locus_tag="COSY_0037"
                     /note="Subunit I/III interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238834"
     misc_feature    38199..38201
                     /gene="coxC"
                     /locus_tag="COSY_0037"
                     /note="Subunit III/VIb interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238834"
     misc_feature    order(38280..38288,38337..38339,38415..38417,38445..38453,
                     38475..38483)
                     /gene="coxC"
                     /locus_tag="COSY_0037"
                     /note="Subunit III/VIa interface; other site"
                     /db_xref="CDD:238834"
     misc_feature    38373..38375
                     /gene="coxC"
                     /locus_tag="COSY_0037"
                     /note="Subunit III/Vb interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238834"
     gene            38756..38983
                     /locus_tag="COSY_0038"
                     /db_xref="GeneID:5172146"
     CDS             38756..38983
                     /locus_tag="COSY_0038"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218901.1"
                     /db_xref="GI:148244207"
                     /db_xref="GeneID:5172146"
                     /translation="MTQIIIVIIIIAILIALSISLLGMLRGGKAGSNKMFKSLVIRVV
                     LSLSLFIIVMFFAYMGWIEPNIIMMDTFSFQ"
     gene            38980..39681
                     /locus_tag="COSY_0039"
                     /db_xref="GeneID:5172098"
     CDS             38980..39681
                     /locus_tag="COSY_0039"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218902.1"
                     /db_xref="GI:148244208"
                     /db_xref="GeneID:5172098"
                     /translation="MIKHTIFIPIILIFLIIYGLISLGFWQIDRADEKRVIENKIILA
                     QQKPVQLITNVKELLNKEYHQVLLKGHYDTDKQFIYDNQIVNGNAGYYVLTPFVLSSK
                     TTILVNRGFVPWNGSRGQLVNIKVDNLTRVIKVRLVKPVERIKLKQELITSNFPVLIQ
                     SLNLDELSLLSDYQIVAMLARLDIEDSDGFFRQWQSFYGSVNKHLSYALQWFLMALVL
                     GIISLRLWIKKNKKN"
     misc_feature    39055..39642
                     /locus_tag="COSY_0039"
                     /note="SURF1 superfamily. Surf1/Shy1 has been implicated
                     in the posttranslational steps of the biogenesis of the
                     mitochondrially-encoded Cox1 subunit of cytochrome c
                     oxidase (complex IV). Cytochrome c oxidase (complex IV),
                     the terminal electron-transferring...; Region: SURF1;
                     cd06662"
                     /db_xref="CDD:119401"
     gene            39798..41216
                     /gene="ccoN"
                     /locus_tag="COSY_0040"
                     /db_xref="GeneID:5172617"
     CDS             39798..41216
                     /gene="ccoN"
                     /locus_tag="COSY_0040"
                     /EC_number="1.9.3.1"
                     /note="CcoN; FixN"
                     /codon_start=1
                     /transl_table=11
                     /product="cbb3-type cytochrome c oxidase subunit I"
                     /protein_id="YP_001218903.1"
                     /db_xref="GI:148244209"
                     /db_xref="GeneID:5172617"
                     /translation="MNLTEKYDLGVVKWFAIMATVYLVIGTLLGVYIASELAFPFLND
                     LGTDLPYFQFGRLRPLHTNSVIFAFAGSALMASAFYIVQRTNQTRLWSNKMAWFTFWS
                     WNTVIVLAVITLPLGLTQSREYAELEWPIDILITLAWVSYLYNFIMTIYIRNRNKVPH
                     VYVANWFFMGMMVMVTYLHVINNLSIPVSAFKSYSIFSGVQDAMIQWWWGHNAVGFFL
                     TAGFLGIMYYFVPKQAQRPIYSYRLSVIHFWALMFGYVWLGAHHLQYTALPDWAGSLG
                     ATISLAMIIPSWGGALNGILTLSGAWDRLREDYILRFLIMSLAFYAMSTFEGPVMAAK
                     TVNALSHYTDWTIGHVHSGALGWNIMVAAGAIYHMIEKIYNVKMSQKLLGIHFWIHTI
                     GTVVYIVAMWVSGIMQGLMWRAYDEYGTLAYTFAESVSAMHPYYVMRATGGTLVLLGA
                     IIMLINIVTTIRRSGSGQIANV"
     misc_feature    39798..41207
                     /gene="ccoN"
                     /locus_tag="COSY_0040"
                     /note="cbb3-type cytochrome c oxidase subunit I;
                     Provisional; Region: PRK14488"
                     /db_xref="CDD:237726"
     misc_feature    order(39816..39818,39837..39839,39849..39854,39864..39866,
                     40026..40028,40827..40829,40848..40850,40857..40862,
                     41031..41036,41118..41120)
                     /gene="ccoN"
                     /locus_tag="COSY_0040"
                     /note="Low-spin heme binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238461"
     misc_feature    39828..41135
                     /gene="ccoN"
                     /locus_tag="COSY_0040"
                     /note="Cytochrome C and Quinol oxidase polypeptide I;
                     Region: COX1; pfam00115"
                     /db_xref="CDD:215728"
     misc_feature    order(39894..39896,39903..39905,39936..39938,39945..39947,
                     40122..40127,40143..40145,40155..40157)
                     /gene="ccoN"
                     /locus_tag="COSY_0040"
                     /note="D-pathway; other site"
                     /db_xref="CDD:238461"
     misc_feature    order(40389..40391,40404..40409,40806..40808,40818..40823,
                     41031..41033)
                     /gene="ccoN"
                     /locus_tag="COSY_0040"
                     /note="Putative water exit pathway; other site"
                     /db_xref="CDD:238461"
     misc_feature    order(40428..40430,40578..40583,40842..40844)
                     /gene="ccoN"
                     /locus_tag="COSY_0040"
                     /note="Binuclear center (active site) [active]"
                     /db_xref="CDD:238461"
     misc_feature    order(40428..40430,40440..40442,40473..40475,40578..40583,
                     40656..40658,40665..40667)
                     /gene="ccoN"
                     /locus_tag="COSY_0040"
                     /note="K-pathway; other site"
                     /db_xref="CDD:238461"
     misc_feature    order(40581..40583,40818..40823,41031..41036)
                     /gene="ccoN"
                     /locus_tag="COSY_0040"
                     /note="Putative proton exit pathway; other site"
                     /db_xref="CDD:238461"
     gene            41231..41962
                     /gene="ccoO"
                     /locus_tag="COSY_0041"
                     /db_xref="GeneID:5172039"
     CDS             41231..41962
                     /gene="ccoO"
                     /locus_tag="COSY_0041"
                     /EC_number="1.9.3.1"
                     /note="CcoO; FixO"
                     /codon_start=1
                     /transl_table=11
                     /product="cbb3-type cytochrome c oxidase subunit II"
                     /protein_id="YP_001218904.1"
                     /db_xref="GI:148244210"
                     /db_xref="GeneID:5172039"
                     /translation="MVNRNVKESLQVKLEKNIFGMYLFMALSVSLAGIVEIVPLFTNP
                     EAVKDEVIVADGSTKSLLWLRSKGQSLSDWKPGDGVRPLTALELAGRDIYQREGCYLC
                     HSQMIRPFRDEKERYGHFSLAVESIYDHPFQWGSKRTGPDLARLGGKYSDEWHILHLR
                     HPQAVVPESVMPKYRFLENALVDGDVISTHMSGLSKVGVPYTKEDIVQAPAFVKGKNE
                     MDAMVAYLQSLGNMIKFEDGVTYRE"
     misc_feature    41255..41935
                     /gene="ccoO"
                     /locus_tag="COSY_0041"
                     /note="Cbb3-type cytochrome oxidase, cytochrome c subunit
                     [Energy production and conversion]; Region: CcoO; COG2993"
                     /db_xref="CDD:225540"
     misc_feature    41267..41950
                     /gene="ccoO"
                     /locus_tag="COSY_0041"
                     /note="cbb3-type cytochrome c oxidase subunit II;
                     Provisional; Region: PRK14487"
                     /db_xref="CDD:237725"
     gene            41962..42102
                     /gene="ccoQ"
                     /locus_tag="COSY_0042"
                     /db_xref="GeneID:5172073"
     CDS             41962..42102
                     /gene="ccoQ"
                     /locus_tag="COSY_0042"
                     /EC_number="1.9.3.1"
                     /codon_start=1
                     /transl_table=11
                     /product="cbb3-type cytochrome c oxidase subunit IV"
                     /protein_id="YP_001218905.1"
                     /db_xref="GI:148244211"
                     /db_xref="GeneID:5172073"
                     /translation="MTLVDKFGAVIAVVIFLLLAISYFYAFRPKNKKKFEALRNFVND
                     KD"
     gene            42121..43023
                     /gene="ccoP"
                     /locus_tag="COSY_0043"
                     /db_xref="GeneID:5172090"
     CDS             42121..43023
                     /gene="ccoP"
                     /locus_tag="COSY_0043"
                     /EC_number="1.9.3.1"
                     /codon_start=1
                     /transl_table=11
                     /product="cbb3-type cytochrome c oxidase subunit III"
                     /protein_id="YP_001218906.1"
                     /db_xref="GI:148244212"
                     /db_xref="GeneID:5172090"
                     /translation="MSEQKNSFPGENNTGHFWDEENDIRELNNPPPRWYMLALYMGTL
                     AVIVYTFYYPTIPWFGEHNKGFASWTQISEMNESVAKLEIYREERFADIEKAIAEKSL
                     EEIVLDDELRTYAIKTSKVLFGDNCSACHGAAGQGNIGFPVLADDDWLYGGKLEQIST
                     SITSGRKGRMPARMLGISDAEASTLATFLIEIGKGKKGNSDLASKALYMNKGCIACHA
                     PNMKGNQLLGSVNLSDGIYRFKADDQHASIVRIILHGVNQVNDPLTQDAVMPSFGHSS
                     IINALQIKKLAIYVHQLGGGVSVK"
     misc_feature    42160..43008
                     /gene="ccoP"
                     /locus_tag="COSY_0043"
                     /note="cytochrome c oxidase, cbb3-type, subunit III;
                     Region: ccoP; TIGR00782"
                     /db_xref="CDD:129864"
     misc_feature    42478..42687
                     /gene="ccoP"
                     /locus_tag="COSY_0043"
                     /note="Cytochrome c; Region: Cytochrom_C; pfam00034"
                     /db_xref="CDD:215669"
     misc_feature    42733..42990
                     /gene="ccoP"
                     /locus_tag="COSY_0043"
                     /note="Cytochrome C oxidase, cbb3-type, subunit III;
                     Region: Cytochrome_CBB3; pfam13442"
                     /db_xref="CDD:205620"
     gene            43138..43213
                     /locus_tag="COSY_t01"
                     /db_xref="GeneID:5329743"
     tRNA            43138..43213
                     /locus_tag="COSY_t01"
                     /product="tRNA-Thr"
                     /db_xref="GeneID:5329743"
     gene            complement(43633..44001)
                     /locus_tag="COSY_0044"
                     /db_xref="GeneID:5172087"
     CDS             complement(43633..44001)
                     /locus_tag="COSY_0044"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218907.1"
                     /db_xref="GI:148244213"
                     /db_xref="GeneID:5172087"
                     /translation="MPNEQILLLNNTKLWLIDVELEQANLISTTNLTQTPLYWFINRP
                     IDSNHIPQYIYTKDKINWYKTQQTNQLNFGLKDNMLKAISLNNKLNQTILLTFDSIII
                     NPNIESNAFELNLKTGFDIQ"
     misc_feature    complement(43669..>43998)
                     /locus_tag="COSY_0044"
                     /note="Outer membrane lipoprotein carrier protein LolA;
                     Region: LolA; cl17548"
                     /db_xref="CDD:248102"
     gene            complement(44001..44201)
                     /locus_tag="COSY_0045"
                     /db_xref="GeneID:5171908"
     CDS             complement(44001..44201)
                     /locus_tag="COSY_0045"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218908.1"
                     /db_xref="GI:148244214"
                     /db_xref="GeneID:5171908"
                     /translation="MTKFISTLMLVFSSFANSNYDFSNFFGSFERLSANFTQHTYNNT
                     GTLLTKSSGTLLFKRPQQLGIS"
     gene            complement(44194..46470)
                     /gene="ftsK"
                     /locus_tag="COSY_0046"
                     /db_xref="GeneID:5172187"
     CDS             complement(44194..46470)
                     /gene="ftsK"
                     /locus_tag="COSY_0046"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="YP_001218909.1"
                     /db_xref="GI:148244215"
                     /db_xref="GeneID:5172187"
                     /translation="MKKNKKISTKRYQQKPRTKIASEILFIFLSTIGLIFLSALVTYS
                     ANENPWSGNVTLIAPVANLAGVFGAYLSDISLSNLGYSAYLIPVSLIWLGWKIHKNTE
                     QKKLKYLTIAIRFISLMTLITFSAAFLVQNFTDIGASGGYIGISIHRYFNVLFGSASL
                     IIYLSIIMISFSIVSSSSWINIFSFTNNMLNNLLKKMRYIRTQVKTIKVSTPIKQSST
                     KTSILTEIKRSKEKPNKSFKKVISSNLFNTITITGLPNVDLLDEPTINTTGYSKEILE
                     KMSRQVEVKLKDFGFDVLVTTVTPGPVVTQFELSLAPGIKVSQIINLNKDLARALLVK
                     SVRIVDIIPGKPVIGLEIPNTQREIINLKEIFSSENFIKSDSALTLGLGKDINGIPII
                     TNLTKMPHLLVAGATGMGKSIGLNTMILSVLFKAKPEEVRIIMIDPKIVELACYAGIP
                     HLLTPVVTDMNQAASALYWCVNEMERRYSLLAKFGVRHIEGFNKKIKKSKNKKEPLFY
                     PLFNQNTTNESKTTTELEALPMIMIVIDEYADMLGTLAQEDRTKAKRVEALIIRLAQK
                     SRAAGIHIIIATQRPSVDVITGLIKSNIPTRIAFKVSSKVDSRTILDQSGAEQLLGMG
                     DMLYMKPGMSHLIRVHGAFVDDGEIERVVNFLKDNHETNYLDDILNINSKSNNLQDLN
                     KISNISCELDVLYNKAVKIVTLSQRASISSLQRRMRIGYNRAALIIEDMEANGIVSSM
                     NSAGNRKVLAPIPITTND"
     misc_feature    complement(46003..46416)
                     /gene="ftsK"
                     /locus_tag="COSY_0046"
                     /note="Domain of unknown function (DUF4117); Region:
                     DUF4117; pfam13491"
                     /db_xref="CDD:222173"
     misc_feature    complement(44722..45387)
                     /gene="ftsK"
                     /locus_tag="COSY_0046"
                     /note="FtsK/SpoIIIE family; Region: FtsK_SpoIIIE;
                     pfam01580"
                     /db_xref="CDD:216584"
     misc_feature    complement(44218..44403)
                     /gene="ftsK"
                     /locus_tag="COSY_0046"
                     /note="Ftsk gamma domain; Region: Ftsk_gamma; pfam09397"
                     /db_xref="CDD:220220"
     gene            46519..47463
                     /gene="trxB"
                     /locus_tag="COSY_0047"
                     /db_xref="GeneID:5171987"
     CDS             46519..47463
                     /gene="trxB"
                     /locus_tag="COSY_0047"
                     /EC_number="1.8.1.9"
                     /note="thioredoxin reductase (NADPH)"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="YP_001218910.1"
                     /db_xref="GI:148244216"
                     /db_xref="GeneID:5171987"
                     /translation="MSENKHCKVLIIGSGPAGYSAAVYAARANLTPVVVSGMEQGGQL
                     MNTTDVDNWPGDDAGVQGPDLMARMKKHAEYFDTQVINDTIISVNFVKRPFVLKGEII
                     TYTADSVIIATGASARYLGLESEEEFKGKGVSACATCDGFFYRGKKVAVIGGGNTAVE
                     EALFLSNIVDHVTIVHRKHKFSSEKILSDQLIEKARTGNITIEYNHNLDEVLGDVNGV
                     TGIRLKNNNNKIKDIDVHGVFIAIGHTPNTAIFKGHLEMINDYIKVQSGTQGNATQTS
                     IEGVFAAGDVSDYVYRQAITSAGSGCMSALDAERFLGE"
     misc_feature    46519..47454
                     /gene="trxB"
                     /locus_tag="COSY_0047"
                     /note="thioredoxin reductase; Provisional; Region:
                     PRK10262"
                     /db_xref="CDD:182343"
     misc_feature    <46669..47052
                     /gene="trxB"
                     /locus_tag="COSY_0047"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; cl17500"
                     /db_xref="CDD:248054"
     misc_feature    46960..47175
                     /gene="trxB"
                     /locus_tag="COSY_0047"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:215691"
     gene            47513..47588
                     /locus_tag="COSY_t02"
                     /db_xref="GeneID:5329754"
     tRNA            47513..47588
                     /locus_tag="COSY_t02"
                     /product="tRNA-Phe"
                     /db_xref="GeneID:5329754"
     gene            complement(48071..49033)
                     /gene="pyrB"
                     /locus_tag="COSY_0049"
                     /db_xref="GeneID:5172005"
     CDS             complement(48071..49033)
                     /gene="pyrB"
                     /locus_tag="COSY_0049"
                     /EC_number="2.1.3.2"
                     /note="catalyzes the transfer of the carbamoyl moiety from
                     carbamoyl phosphate to L- aspartate in pyrimidine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="YP_001218911.1"
                     /db_xref="GI:148244217"
                     /db_xref="GeneID:5172005"
                     /translation="MKKNLISNHIQLNDSGKLIHLLGLEGLSKQHLTHILDKADSLID
                     TSGNLKKSKALDDMSIANLFFEPSTRTRNTFEIAAMRSSANVINVDLANSALKKNEDL
                     LDTMRTLKAMQIDMFVIRHKQNGLPHHVAKYLEGVSILNAGDGINAHPTQALLDMLSI
                     RQHKKTFENLSVAIVGDIIHSRVAHSGIQALKTLGTTDIRLIAPKILQYNSEPCSEVS
                     CFDDIEPGLKDCDVVIVLRLQKERMIEANIPNEQEYFNNFGLTPKRLALTKSDAIVMH
                     PGPINRGVEIDSIVADGNQSIILQQVTDGIAIRMAVMQILANKS"
     misc_feature    complement(48074..48991)
                     /gene="pyrB"
                     /locus_tag="COSY_0049"
                     /note="aspartate carbamoyltransferase catalytic subunit;
                     Provisional; Region: pyrB; PRK00856"
                     /db_xref="CDD:234849"
     misc_feature    complement(48545..48976)
                     /gene="pyrB"
                     /locus_tag="COSY_0049"
                     /note="Aspartate/ornithine carbamoyltransferase,
                     carbamoyl-P binding domain; Region: OTCace_N; pfam02729"
                     /db_xref="CDD:217204"
     misc_feature    complement(48086..48532)
                     /gene="pyrB"
                     /locus_tag="COSY_0049"
                     /note="Aspartate/ornithine carbamoyltransferase, Asp/Orn
                     binding domain; Region: OTCace; pfam00185"
                     /db_xref="CDD:215776"
     gene            complement(49014..49442)
                     /locus_tag="COSY_0050"
                     /db_xref="GeneID:5172374"
     CDS             complement(49014..49442)
                     /locus_tag="COSY_0050"
                     /note="Similar to Holliday junction resolvase."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218912.1"
                     /db_xref="GI:148244218"
                     /db_xref="GeneID:5172374"
                     /translation="MNINTYLGFDIGTKRTGVAIANSLTMRATGIAVIKHHKDNSTNW
                     VELDEVINSHNIKLFIVGLPFDKQGKEQIMTFIAKSFGKKLKNRYQIEVEFIDEYLSS
                     NEAKKLLKYNHHHHNAQRGNVDKQSSQLILQTWLNEKKFD"
     misc_feature    complement(49029..49430)
                     /locus_tag="COSY_0050"
                     /note="Uncharacterized protein family (UPF0081); Region:
                     UPF0081; pfam03652"
                     /db_xref="CDD:217659"
     gene            complement(49439..49720)
                     /locus_tag="COSY_0051"
                     /db_xref="GeneID:5172595"
     CDS             complement(49439..49720)
                     /locus_tag="COSY_0051"
                     /note="Similar to the C-terminal region of membrane-bound
                     lytic transglycolase-related protein in Thiobacillus
                     denitrificans , peptidoglycan-binding domain 1."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218913.1"
                     /db_xref="GI:148244219"
                     /db_xref="GeneID:5172595"
                     /translation="MLFSGGIAQFYMYYLSDRLIGLNQLFAKSITEPSLSNDNIKYIQ
                     NTLNKLGFNTGEPNGISGQKTRCTTRAYQKANKLPIDGYVGYQLLQQLQ"
     misc_feature    complement(49466..49615)
                     /locus_tag="COSY_0051"
                     /note="Putative peptidoglycan binding domain; Region:
                     PG_binding_1; pfam01471"
                     /db_xref="CDD:216518"
     gene            complement(49850..50515)
                     /locus_tag="COSY_0052"
                     /db_xref="GeneID:5172367"
     CDS             complement(49850..50515)
                     /locus_tag="COSY_0052"
                     /note="Similar to the N-terminal region of membrane-bound
                     lytic transglycolase-related protein in Thiomicrospira
                     crunogena XCL-2."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218914.1"
                     /db_xref="GI:148244220"
                     /db_xref="GeneID:5172367"
                     /translation="MIVHYKAIQLGISQTTINNYFNDLIPNPKVLKYDRNQTKFNLNF
                     WHYLNSRVNQNRLDKGLIKLKKYQKYLQENYKKYGIPTHIIVALWGLETNYGKNIGKI
                     NIIRSLATLSFDKRRREFFTHELLTLLKLIDEDRLPLNTQGSWASAMGSIQFIPTNVA
                     TYDIDANLDGKIHLWHTQEDIFASAVYFLKNICWYQGERRGRKVNIPKDFNYQLTNLS
                     IKR"
     misc_feature    complement(<49853..50500)
                     /locus_tag="COSY_0052"
                     /note="Transglycosylase SLT domain; Region: SLT_2;
                     pfam13406"
                     /db_xref="CDD:222107"
     misc_feature    complement(<49895..50383)
                     /locus_tag="COSY_0052"
                     /note="murein hydrolase B; Provisional; Region: PRK10760;
                     cl17906"
                     /db_xref="CDD:248460"
     gene            50634..51548
                     /gene="apbE"
                     /locus_tag="COSY_0053"
                     /db_xref="GeneID:5172417"
     CDS             50634..51548
                     /gene="apbE"
                     /locus_tag="COSY_0053"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamin biosynthesis lipoprotein ApbE"
                     /protein_id="YP_001218915.1"
                     /db_xref="GI:148244221"
                     /db_xref="GeneID:5172417"
                     /translation="MFIVFIFLFLSSCVSETAQTITGTTMGTDYSIKVLNTQISKLII
                     DKRLNEIEKIFSTWDETSELSKLNRAPVNQWIKVSDELFFVLLQAKKIYKQTQGFFDP
                     GIGRLIDVWGFGVIKTQVKPNKEKIAKALAISSIEYIHLGDLRVKKLKDVYINLSAIV
                     KGYSVDIVANMLIQQGLKNFIVEIGGEVMAQGQWTIGIEKPNHSLPIAIELQNLAIAT
                     SGDYRNYFVWQEKKYQHILNPSTGLPANTDLSSVSVIHDSAMIADAYATAMMAMGSQK
                     ARILAQQLNLSVVFILNQWYDFEVLQFH"
     misc_feature    50637..51506
                     /gene="apbE"
                     /locus_tag="COSY_0053"
                     /note="Membrane-associated lipoprotein involved in
                     thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE;
                     COG1477"
                     /db_xref="CDD:224394"
     misc_feature    50775..51506
                     /gene="apbE"
                     /locus_tag="COSY_0053"
                     /note="ApbE family; Region: ApbE; pfam02424"
                     /db_xref="CDD:217027"
     gene            52239..52631
                     /locus_tag="COSY_0054"
                     /db_xref="GeneID:5172107"
     CDS             52239..52631
                     /locus_tag="COSY_0054"
                     /note="crcB-family inner membrane protein in chromosome
                     condensation"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218916.1"
                     /db_xref="GI:148244222"
                     /db_xref="GeneID:5172107"
                     /translation="MSVLFTIFVIGIGATIGASMRYYLTQLMNATLISDFPYSTLAVN
                     ILGSFLAGILVVIILERATLHEAYRLMLLIGLTGSLTTMSTLSWESIEMISFGYYGQA
                     GLNILLNVVLSLLATGIGVILGRYFLIS"
     misc_feature    52245..52622
                     /locus_tag="COSY_0054"
                     /note="Integral membrane protein possibly involved in
                     chromosome condensation [Cell division and chromosome
                     partitioning]; Region: CrcB; COG0239"
                     /db_xref="CDD:223317"
     gene            complement(52628..53590)
                     /gene="gshB"
                     /locus_tag="COSY_0055"
                     /db_xref="GeneID:5172348"
     CDS             complement(52628..53590)
                     /gene="gshB"
                     /locus_tag="COSY_0055"
                     /EC_number="6.3.2.3"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthetase"
                     /protein_id="YP_001218917.1"
                     /db_xref="GI:148244223"
                     /db_xref="GeneID:5172348"
                     /translation="MKKIKIAVLMDNINNINPKKDSSLAMMLEASKRGWEIYTFNTCD
                     LFAQDGSVFANCAKTTVHDNLNHWFKKETNTIMILSEFNVILMRKDPPFNMNYIYATY
                     LLEQSENKNTLIINKPQSLRDANEKLFALNFPHCIPKTLISSNQMQIKTFIKIQNTAI
                     IKPLDGMGGHDIFKFKTNDIKIDAILKRLTNNGKKPIMVQEFLPDITKGDKRILLING
                     KPVDYALARIPAKGNFKGNLAAGAIGIGQPLSKHDYYLCKQISPTLKAKGLIFVGLDV
                     IGDYITEINVTSPTCIRELDKQFNLNIAGELFDVIEQKIKISHY"
     misc_feature    complement(52643..53581)
                     /gene="gshB"
                     /locus_tag="COSY_0055"
                     /note="glutathione synthetase; Provisional; Region:
                     PRK05246"
                     /db_xref="CDD:235371"
     misc_feature    complement(53225..53581)
                     /gene="gshB"
                     /locus_tag="COSY_0055"
                     /note="Prokaryotic glutathione synthetase, N-terminal
                     domain; Region: GSH-S_N; pfam02951"
                     /db_xref="CDD:190485"
     misc_feature    complement(52694..53215)
                     /gene="gshB"
                     /locus_tag="COSY_0055"
                     /note="Prokaryotic glutathione synthetase, ATP-grasp
                     domain; Region: GSH-S_ATP; pfam02955"
                     /db_xref="CDD:202486"
     gene            53629..53705
                     /locus_tag="COSY_t03"
                     /db_xref="GeneID:5329746"
     tRNA            53629..53705
                     /locus_tag="COSY_t03"
                     /product="tRNA-Met"
                     /db_xref="GeneID:5329746"
     gene            53808..54269
                     /locus_tag="COSY_0057"
                     /db_xref="GeneID:5171850"
     CDS             53808..54269
                     /locus_tag="COSY_0057"
                     /note="in Streptococcus pneumoniae this gene was found to
                     be essential; structure determination of the Streptococcus
                     protein shows that it is similar to a number of other
                     proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218918.1"
                     /db_xref="GI:148244224"
                     /db_xref="GeneID:5171850"
                     /translation="MARVTDKITHLIKPVIEGMGYELLGIEYVASGKYSILRIFIDTN
                     KSISVNDCEIVSRQLSSIFDIEEPISGQYNLEVSSPGIERPLFHKGHYQCFLGFNVKL
                     HMFRPISGQSNFFGVIGSVSEINNTIELVGELGAIILDIDLIKKANLVVDF"
     misc_feature    53808..54266
                     /locus_tag="COSY_0057"
                     /note="ribosome maturation protein RimP; Reviewed; Region:
                     PRK00092"
                     /db_xref="CDD:234627"
     misc_feature    53823..>54128
                     /locus_tag="COSY_0057"
                     /note="Sm and related proteins; Region: Sm_like; cl00259"
                     /db_xref="CDD:241733"
     misc_feature    54048..54266
                     /locus_tag="COSY_0057"
                     /note="Bacillus subtilis YxlS-like, C-terminal domain;
                     Region: YlxS_C; cd01734"
                     /db_xref="CDD:212481"
     misc_feature    order(54114..54116,54120..54122,54141..54143,54147..54149,
                     54165..54167,54186..54188,54213..54221,54225..54230,
                     54234..54251)
                     /locus_tag="COSY_0057"
                     /note="putative oligomer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:212481"
     misc_feature    order(54171..54173,54177..54179,54225..54227)
                     /locus_tag="COSY_0057"
                     /note="putative RNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:212481"
     gene            54310..55785
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /db_xref="GeneID:5172308"
     CDS             54310..55785
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="N utilization substance protein A"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="YP_001218919.1"
                     /db_xref="GI:148244225"
                     /db_xref="GeneID:5172308"
                     /translation="MDGKELFLMVEAISNEKNISKEEVLESLEKALAIATKKRNNIDA
                     YVEINRQTGEFLTFRQWMVVADGELFVDDDGTEFDLELHIYEKDTDGLVVDDYMRKPI
                     ETQEFGRIAAQIVKQVIIQKVREAEREVIVNDYSSRIGEVIMVTVKRVDRGNIYVDMG
                     GVDGMIPKFDLIPNESVRKNDRLRAYIKEVKSSIRGVQIFLSRSVSEMMIELFKMEVP
                     EISAGVIEIMGGSRDPGLRSKLAVRAKDKRIDPIGSCIGMRGARVQAVSNELNAERVD
                     IILWDEDPAQFVINAMAPAEVSSIIVDENKHSMDIAVEDEQLALAIGRGGQNIKLASR
                     LTGWKLNVMSTIQADEEQVQEMQKISDKLADQLGVDSEVAGVLIEEGFDSVDELVDAD
                     TQVLGNIEEFDASMVEELQERASDAQLVQALGDAEASEILMSVEGVNEDLASVLIEVD
                     IFTVDDLAELSIDELLDIQDMDIEIASSIIMTARENEGWFD"
     misc_feature    54319..55725
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="transcription elongation factor NusA; Validated;
                     Region: nusA; PRK09202"
                     /db_xref="CDD:236410"
     misc_feature    54322..54699
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="NusA N-terminal domain; Region: NusA_N; pfam08529"
                     /db_xref="CDD:219884"
     misc_feature    54718..54918
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="S1_NusA: N-utilizing substance A protein (NusA),
                     S1-like RNA-binding domain. S1-like RNA-binding domains
                     are found in a wide variety of RNA-associated proteins.
                     NusA is a transcription elongation factor containing an
                     N-terminal catalytic domain and three...; Region: S1_NusA;
                     cd04455"
                     /db_xref="CDD:239902"
     misc_feature    order(54751..54753,54775..54777,54802..54804,54808..54810)
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:239902"
     misc_feature    order(54757..54759,54769..54771,54796..54798,54802..54804,
                     54901..54903)
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239902"
     misc_feature    55009..55215
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="NusA-like KH domain; Region: KH_5; pfam13184"
                     /db_xref="CDD:205365"
     misc_feature    55159..55338
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="NusA_K homology RNA-binding domain (KH). NusA is an
                     essential multifunctional transcription elongation factor
                     that is universally conserved among prokaryotes and
                     archaea. NusA anti-termination function plays an important
                     role in the expression of...; Region: NusA_KH; cd02134"
                     /db_xref="CDD:239049"
     misc_feature    55276..55287
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="G-X-X-G motif; other site"
                     /db_xref="CDD:239049"
     misc_feature    55414..55560
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="transcription termination factor NusA, C-terminal
                     duplication; Region: nusA_Cterm_rpt; TIGR01954"
                     /db_xref="CDD:131009"
     misc_feature    55621..55764
                     /gene="nusA"
                     /locus_tag="COSY_0058"
                     /note="transcription termination factor NusA, C-terminal
                     duplication; Region: nusA_Cterm_rpt; TIGR01954"
                     /db_xref="CDD:131009"
     gene            55839..58286
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /db_xref="GeneID:5171913"
     CDS             55839..58286
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="Protects formylmethionyl-tRNA from spontaneous
                     hydrolysis and promotes its binding to the 30S ribosomal
                     subunits during initiation of protein synthesis. Also
                     involved in the hydrolysis of GTP during the formation of
                     the 70S ribosomal complex"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="YP_001218920.1"
                     /db_xref="GI:148244226"
                     /db_xref="GeneID:5171913"
                     /translation="MAHTVQTLSKLLKKTPDEVVTILANAGVDGKNSDSVISAEERKI
                     LMSSLSKRPIRRSSMSVFRKAGTKSNAVSVSDVKVKVRSKRLTQPITMIDEQSKVVAN
                     EMARAALAALDAGRNADEILLAQDARRLEMVRLQKAQVEVVEIQKETVKKVQEKEAEK
                     KVEKLKTADKPKEGNKPKRLRNTSSDNNTRKQLHVARHNPNRRLKKKDRTHLSQKIQA
                     EQAQHAFQKPIEKVIHEVAIVGNIKVTELAQKMATKAGEVLKVLMGMGVMVTLNDVID
                     QDTALLVVEEMGHKGIISVEETIEDVLIEQLKYNEHESARPPIVTIMGHVDHGKTSLL
                     DYIRQAKVAHGEVGGITQHIGAYQVQSNGNIITFIDTPGHAAFSKMRFRGANVTDIVI
                     LVVAADDGVMPQTIESIKHTQIVGVPMIVAINKIDKEGTDVDKIKQVLSTYDVISEDW
                     GGDVIMVPVSAHTGEGVDALLDAISLTAEILEFSAVSEGPAHGTVLEARLEKGRGKVT
                     TILVQSGTLNKGDIMIAGFEYGKVKQIVDDKGKILKLAMPSMPVEVLGLSGVPNSGDE
                     VIVVGSERKAREVADFRKSKDREVQLQKQQASKMENFLMKMEKGDISTVNVLLKADVR
                     GSAQALIEALEELSTDEVRVKVVSSGVGGINNTDITLAATSSALVLGFNVRADAVARK
                     TADNEGVRVEYYSIIYNLINDVKAIMSGLLSPELSENIIGIASVKNIFKSQKMGDIAG
                     CMVDEGMVKRDSLIRVLRDSVVIFDGKLESLRRFKDDVNEVKSGTECGIGVLNYTDVQ
                     PGDQIEIFERVERARIL"
     misc_feature    56544..58283
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="translation initiation factor IF-2; Region: IF-2;
                     TIGR00487"
                     /db_xref="CDD:232995"
     misc_feature    56790..57281
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="Initiation Factor 2 (IF2)/ eukaryotic Initiation
                     Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887"
                     /db_xref="CDD:206674"
     misc_feature    56808..56831
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="G1 box; other site"
                     /db_xref="CDD:206674"
     misc_feature    order(56811..56813,56817..56819,56829..56834,56841..56843,
                     56850..56855,56901..56906,56958..56963,57030..57035,
                     57138..57140,57150..57152)
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="putative GEF interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:206674"
     misc_feature    order(56814..56834,56961..56963,57108..57113,57117..57122,
                     57216..57224)
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206674"
     misc_feature    56883..56903
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206674"
     misc_feature    56889..56891
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="G2 box; other site"
                     /db_xref="CDD:206674"
     misc_feature    56946..56957
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="G3 box; other site"
                     /db_xref="CDD:206674"
     misc_feature    56952..57008
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206674"
     misc_feature    57108..57119
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="G4 box; other site"
                     /db_xref="CDD:206674"
     misc_feature    57216..57224
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="G5 box; other site"
                     /db_xref="CDD:206674"
     misc_feature    57309..57590
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="This family represents the domain II of bacterial
                     Initiation Factor 2 (IF2) and its eukaryotic mitochondrial
                     homologue mtIF2. IF2, the largest initiation factor is an
                     essential GTP binding protein. In E. coli three natural
                     forms of IF2 exist in the cell; Region: IF2_mtIF2_II;
                     cd03702"
                     /db_xref="CDD:239673"
     misc_feature    57633..57956
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="Translation-initiation factor 2; Region: IF-2;
                     pfam11987"
                     /db_xref="CDD:221359"
     misc_feature    58002..58253
                     /gene="infB"
                     /locus_tag="COSY_0059"
                     /note="mtIF2_IVc: this family represents the C2 subdomain
                     of domain IV of mitochondrial translation initiation
                     factor 2 (mtIF2) which adopts a beta-barrel fold
                     displaying a high degree of structural similarity with
                     domain II of the translation elongation factor...; Region:
                     mtIF2_IVc; cd03692"
                     /db_xref="CDD:239663"
     gene            58301..58645
                     /gene="rbfA"
                     /locus_tag="COSY_0060"
                     /db_xref="GeneID:5172676"
     CDS             58301..58645
                     /gene="rbfA"
                     /locus_tag="COSY_0060"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="YP_001218921.1"
                     /db_xref="GI:148244227"
                     /db_xref="GeneID:5172676"
                     /translation="MLEQEQASYRVERINELIRRELTLLLRTSIKDPRLRDMIITDVL
                     ISRDLSSAKVFYTVIKEDKKMIEPLLDKASGFFRIHLSKTIDLRHTPVLRFIFDSAPN
                     TGARIEQLLSKL"
     misc_feature    58388..58633
                     /gene="rbfA"
                     /locus_tag="COSY_0060"
                     /note="Ribosome-binding factor A; Region: RBFA; pfam02033"
                     /db_xref="CDD:216854"
     gene            58668..59576
                     /gene="truB"
                     /locus_tag="COSY_0061"
                     /db_xref="GeneID:5172085"
     CDS             58668..59576
                     /gene="truB"
                     /locus_tag="COSY_0061"
                     /EC_number="4.2.1.70"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine synthase B"
                     /protein_id="YP_001218922.1"
                     /db_xref="GI:148244228"
                     /db_xref="GeneID:5172085"
                     /translation="MLRRNPKGRSINGIVLLDKDIGLSSNAALQKVKRLFFAKKAGHT
                     GALDFSASGILPICLGQATKIAQFLLEDDKRYFVRGKLGQISDTGDCEGSIIKTQPFE
                     HLSDSEIAKVTASFKGNIFQIPPMYSALKRDGQPLYKLARKGIEVERESRLVTIYKII
                     YLGYKNGILSLEVTCSKGTYIRTLIEDIGEKLSCGAHVIELRRTGFAHIDIRQTLTFS
                     ELEILASNDYQALDEKILASEDMLLGLEDVYLSKVQSLDIKFGREIQTDKQGLLKVKL
                     FNEKKQFLGIGQCQGNGIILPKKLFI"
     misc_feature    58674..59570
                     /gene="truB"
                     /locus_tag="COSY_0061"
                     /note="tRNA pseudouridine synthase B; Provisional; Region:
                     truB; PRK05033"
                     /db_xref="CDD:235333"
     misc_feature    58704..59336
                     /gene="truB"
                     /locus_tag="COSY_0061"
                     /note="Pseudouridine synthase, Escherichia coli TruB like;
                     Region: PseudoU_synth_EcTruB; cd02573"
                     /db_xref="CDD:211339"
     misc_feature    order(58737..58739,58743..58745,58752..58754,58788..58796,
                     58800..58814,58854..58856,58863..58868,58875..58877,
                     58887..58889,58893..58895,59046..59060,59121..59123,
                     59196..59213,59274..59276)
                     /gene="truB"
                     /locus_tag="COSY_0061"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:211339"
     misc_feature    order(58800..58811,59211..59213)
                     /gene="truB"
                     /locus_tag="COSY_0061"
                     /note="active site"
                     /db_xref="CDD:211339"
     misc_feature    59409..59570
                     /gene="truB"
                     /locus_tag="COSY_0061"
                     /note="Pseudouridine synthase II TruB, C-terminal; Region:
                     TruB-C_2; pfam09157"
                     /db_xref="CDD:220128"
     gene            59816..61099
                     /gene="purD"
                     /locus_tag="COSY_0062"
                     /db_xref="GeneID:5171810"
     CDS             59816..61099
                     /gene="purD"
                     /locus_tag="COSY_0062"
                     /EC_number="6.3.4.13"
                     /note="catalyzes the formation of
                     N(1)-(5-phospho-D-ribosyl)glycinamide from
                     5-phospho-D-ribosylamine and glycine in purine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="YP_001218923.1"
                     /db_xref="GI:148244229"
                     /db_xref="GeneID:5171810"
                     /translation="MKVLVIGGGGREHALAWQCSKFDTVSHVFVAPGNAGTQLETKLT
                     NINILTDDIVGLINFVKTNQVDLTIVGPEAPLVIGIVDRFQYEGLAIFGPTKAASQLE
                     WSKVFCKYFLERHNIPTAHYGVFTEVELAIEYVKNQGTPIVIKADGLASGKGVIIAYT
                     QFEAKNVIIDMLQGNCFGKAGLCVVIEEFLSGEEASFIVMCDGKNILPMATSQDHKAR
                     DNDDKGPNTGGMGAYSPTPIITDEIFQSVMDTIIYPTVNAMAEEGNIYTGFLYVGLMI
                     DQDNNFKVLEYNCRFGDPETQPIMMRLKSNLADLCLLATQQSLDQANIKWDERICLGV
                     VLAAKGYPNTYNTNELIILPEDSQDTKVFHAGTKLENGKVFSSGGRVLCVTALGENIY
                     SAQTKAYKLVKRINWDGSYYRDDIGFKAIKRLYSI"
     misc_feature    59816..61084
                     /gene="purD"
                     /locus_tag="COSY_0062"
                     /note="phosphoribosylamine--glycine ligase; Provisional;
                     Region: PRK00885"
                     /db_xref="CDD:234856"
     misc_feature    59816..60121
                     /gene="purD"
                     /locus_tag="COSY_0062"
                     /note="Phosphoribosylglycinamide synthetase, N domain;
                     Region: GARS_N; pfam02844"
                     /db_xref="CDD:217251"
     misc_feature    60125..60703
                     /gene="purD"
                     /locus_tag="COSY_0062"
                     /note="Phosphoribosylglycinamide synthetase, ATP-grasp (A)
                     domain; Region: GARS_A; pfam01071"
                     /db_xref="CDD:216282"
     misc_feature    60806..61078
                     /gene="purD"
                     /locus_tag="COSY_0062"
                     /note="Phosphoribosylglycinamide synthetase, C domain;
                     Region: GARS_C; pfam02843"
                     /db_xref="CDD:217250"
     gene            complement(61656..62363)
                     /locus_tag="COSY_0063"
                     /db_xref="GeneID:5172412"
     CDS             complement(61656..62363)
                     /locus_tag="COSY_0063"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218924.1"
                     /db_xref="GI:148244230"
                     /db_xref="GeneID:5172412"
                     /translation="MKKFILLTLLMANFLLLTACVSAIQGVSTVSSIISVSNDRRSAG
                     EVLDDKTIALRLFTWSNKDVILNNAHLNFMVYNKTVLITGEVTTPKIRIYVSKQAQLQ
                     VPKISQVFNEIKLGPSNGLLSRAKDSTITIQVEFLFQNQEVFHPTHVQVMTENQVVYL
                     MGAVTKREADMAAKTAAKARGVCKVIKLFDYIKTRPKAEIERDRLKSLENEQKAKLEV
                     KKANLKHQIRVLNRNVH"
     misc_feature    complement(61785..62249)
                     /locus_tag="COSY_0063"
                     /note="outer membrane lipoprotein; Provisional; Region:
                     PRK11023"
                     /db_xref="CDD:182907"
     gene            62682..63512
                     /locus_tag="COSY_0064"
                     /db_xref="GeneID:5172347"
     CDS             62682..63512
                     /locus_tag="COSY_0064"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="YP_001218925.1"
                     /db_xref="GI:148244231"
                     /db_xref="GeneID:5172347"
                     /translation="MNGTLYIIATPIGNLNDITFRAIETLKTVDIILAEDICHSKRLL
                     NHYDITTSMYTFHEHNERCKTPDIINKLLKGKHFALISDAGTPLISDPGHVLVIEAKK
                     VGINVSPIPGSNAMISAISVSGIASNKFSFFGFLPSKQSARLKVIQSIVNINEMAIFY
                     ESPNRILSCAQDLQTVLGNERIVCFAKELTKLFETIKTNTLPQLIDYLQADNTHQKGE
                     FVILISAAKKNNEVSGEEMLNKVLPILLIEMGAAKAARLVAKMTGFDKRYCYQRAIEL
                     "
     misc_feature    62682..63509
                     /locus_tag="COSY_0064"
                     /note="Predicted methyltransferases [General function
                     prediction only]; Region: COG0313"
                     /db_xref="CDD:223390"
     misc_feature    62694..63353
                     /locus_tag="COSY_0064"
                     /note="Ribosomal RNA small subunit methyltransferase I,
                     also known as rRNA (cytidine-2&apos;-O-)-methyltransferase
                     RsmI; Region: RsmI; cd11648"
                     /db_xref="CDD:212507"
     misc_feature    order(62715..62717,62931..62939,62946..62951,63021..63026,
                     63159..63161,63237..63239,63243..63248,63333..63341)
                     /locus_tag="COSY_0064"
                     /note="putative SAM binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212507"
     misc_feature    order(62733..62744,62748..62750,62937..62954,62961..62966,
                     62970..62975,63006..63008,63012..63023,63027..63032,
                     63039..63044,63069..63083)
                     /locus_tag="COSY_0064"
                     /note="putative homodimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:212507"
     gene            complement(63752..64357)
                     /gene="coaE"
                     /locus_tag="COSY_0065"
                     /db_xref="GeneID:5172360"
     CDS             complement(63752..64357)
                     /gene="coaE"
                     /locus_tag="COSY_0065"
                     /EC_number="2.7.1.24"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="YP_001218926.1"
                     /db_xref="GI:148244232"
                     /db_xref="GeneID:5172360"
                     /translation="MSIIKIALTGGIACGKSKVSQILSNLGLDIISLDKLAQKIVKPN
                     TIELKELIKHFGDDILNTNTSLNRSILRKILLEKKSNQKLIEAILHPRILIRMENEIR
                     KLKAKLVVVEVPLLAEKNLTHLFNRAIIINCNKEQQLKRLINRDNIDTNEAKNMVSTQ
                     FSHALRLKLREKLPTDIIENNLEITDLTHKTNQLYKKLINL"
     misc_feature    complement(63755..64351)
                     /gene="coaE"
                     /locus_tag="COSY_0065"
                     /note="Dephospho-CoA kinase [Coenzyme metabolism]; Region:
                     CoaE; COG0237"
                     /db_xref="CDD:223315"
     misc_feature    complement(63800..64345)
                     /gene="coaE"
                     /locus_tag="COSY_0065"
                     /note="Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24)
                     catalyzes the phosphorylation of dephosphocoenzyme A
                     (dCoA) to yield CoA, which is the final step in CoA
                     biosynthesis; Region: DPCK; cd02022"
                     /db_xref="CDD:238980"
     misc_feature    complement(order(63878..63880,64013..64018,64088..64090,
                     64256..64258,64331..64333))
                     /gene="coaE"
                     /locus_tag="COSY_0065"
                     /note="CoA-binding site [chemical binding]; other site"
                     /db_xref="CDD:238980"
     misc_feature    complement(order(63818..63820,63935..63937,64310..64315,
                     64322..64330))
                     /gene="coaE"
                     /locus_tag="COSY_0065"
                     /note="ATP-binding [chemical binding]; other site"
                     /db_xref="CDD:238980"
     gene            64442..64518
                     /locus_tag="COSY_t04"
                     /db_xref="GeneID:5329744"
     tRNA            64442..64518
                     /locus_tag="COSY_t04"
                     /product="tRNA-Met"
                     /db_xref="GeneID:5329744"
     gene            complement(65198..65623)
                     /locus_tag="COSY_0067"
                     /db_xref="GeneID:5172126"
     CDS             complement(65198..65623)
                     /locus_tag="COSY_0067"
                     /codon_start=1
                     /transl_table=11
                     /product="nuclease"
                     /protein_id="YP_001218927.1"
                     /db_xref="GI:148244233"
                     /db_xref="GeneID:5172126"
                     /translation="MKLFLSIIIATLVFQVQSKPQYGTVIVSKVISIYDGDTFRVNID
                     LLPPIVGRNIPIRINGIDTPEIRGKCQYEKNIAIKARDFVRGKLNNAKEIKLTNLQRG
                     KYFRVIANVMVDGVSLEQELLDNGLAYNYYGGKKLSWCK"
     misc_feature    complement(<65216..65623)
                     /locus_tag="COSY_0067"
                     /note="Micrococcal nuclease (thermonuclease) homologs [DNA
                     replication, recombination, and repair]; Region: COG1525"
                     /db_xref="CDD:224442"
     misc_feature    complement(<65225..65521)
                     /locus_tag="COSY_0067"
                     /note="Staphylococcal nuclease homologues. SNase
                     homologues are found in bacteria, archaea, and eukaryotes.
                     They contain no disufide bonds; Region: SNc; cl00140"
                     /db_xref="CDD:241633"
     misc_feature    complement(order(65306..65308,65312..65317,65429..65431,
                     65438..65440,65456..65458,65513..65515))
                     /locus_tag="COSY_0067"
                     /note="Catalytic site; other site"
                     /db_xref="CDD:238102"
     gene            complement(66489..66692)
                     /locus_tag="COSY_0068"
                     /db_xref="GeneID:5172356"
     CDS             complement(66489..66692)
                     /locus_tag="COSY_0068"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218928.1"
                     /db_xref="GI:148244234"
                     /db_xref="GeneID:5172356"
                     /translation="MDTIIKYKYEMDRINSWMEDCYIINQIIKASGLYKFYKNWTDDD
                     DESHMKQHILDTKLSEREFLKKE"
     gene            complement(68273..68479)
                     /locus_tag="COSY_0069"
                     /db_xref="GeneID:5172327"
     CDS             complement(68273..68479)
                     /locus_tag="COSY_0069"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218929.1"
                     /db_xref="GI:148244235"
                     /db_xref="GeneID:5172327"
                     /translation="MYKSYQIKKLNQEDTIRDLLVFTDLHRREATNLKWGNINYKDKI
                     SLLTIIKTMKPYAIINILFIGHVE"
     gene            69410..71395
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /db_xref="GeneID:5172345"
     CDS             69410..71395
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /EC_number="2.2.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="YP_001218930.1"
                     /db_xref="GI:148244236"
                     /db_xref="GeneID:5172345"
                     /translation="MPSRRDLANAIRVLSMDAVQRANSGHPGAPMGMADIAQVLWNDH
                     LKYNPMNAKWTNRDRFVLSNGHGSMLIYSLLHLSGYDLNMDDIKDFRQLHARTAGHPE
                     YGYVDGIETTTGPLGQGITNAVGMAIAERTLGAQFNKLGHNIVDHNTYVFMGDGCLME
                     GLSHESCAMAGTLGLGKLIVFWDDNDISIDGHISDWMEKDVASRFESYGWHVVRDVNG
                     HDPDAINSAINAAKDEITKPSFICTRTTIGFGSPNLCGTHNCHGSPLGNEEIAATRKE
                     LGWDFAPFEIPVDIYEGWDHKKKGIADELAWNIKFAAYKAEFSADATEFERRMSGDLP
                     ANFEVEMDQFIAKTQDEMPSIASRQASQRTIEAMGPLLPEMFGGSADLTGSNLTNWSG
                     TVKVNAENANGNYLSWGVREFGMAHMMNGIVLHGGFKVYGATFFMFMEFMRNALRMSA
                     LMKIGTIYVYTHDSIGLGEDGPTHQPVEQLATMRMIPNFQSWRGCDAVESAVSWKMAM
                     LRSDAPTGLVFSRQTLTAMERTSEQVENIEKGGYVLKDCEGLADIIFIATGSEVNLAI
                     EAVAVINAKVRVVSMPCTNAYDDQDQAYKDSVLTPGIKRLAIEAGVADGWYKYVGLDG
                     GVVCMTTFGESAPADQLFKAFGFTIDNVIAKAKAIIG"
     misc_feature    69410..71389
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /note="transketolase; Reviewed; Region: PRK12753"
                     /db_xref="CDD:183723"
     misc_feature    69434..70231
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /note="Thiamine pyrophosphate (TPP) family, Transketolase
                     (TK) subfamily, TPP-binding module; TK catalyzes the
                     transfer of a two-carbon unit from ketose phosphates to
                     aldose phosphates. In heterotrophic organisms, TK provides
                     a link between glycolysis and the...; Region: TPP_TK;
                     cd02012"
                     /db_xref="CDD:238970"
     misc_feature    order(69605..69607,69749..69751,69755..69757,69872..69877,
                     69887..69889,69962..69964,69968..69970,69974..69976,
                     70190..70192)
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238970"
     misc_feature    order(69680..69682,69704..69709,69713..69715,69752..69757,
                     69761..69763,69881..69892,69899..69904,69911..69913,
                     69923..69925,69971..69976,70019..70021)
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238970"
     misc_feature    70484..70972
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /note="Pyrimidine (PYR) binding domain of
                     1-deoxy-D-xylulose-5-phosphate synthase (DXS),
                     transketolase (TK), and related proteins; Region:
                     TPP_PYR_DXS_TK_like; cd07033"
                     /db_xref="CDD:132916"
     misc_feature    order(70526..70528,70532..70534,70550..70552,70619..70621,
                     70628..70630,70634..70651,70658..70663,70667..70675,
                     70730..70732,70739..70744,70817..70819,70826..70828,
                     70874..70879,70943..70945)
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    order(70550..70552,70628..70630,70637..70645,70727..70732,
                     70736..70738,70817..70819,70823..70825,70850..70855,
                     70859..70864,70868..70870)
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    order(70637..70639,70643..70645,70721..70723,70730..70732)
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    71030..71365
                     /gene="tktA"
                     /locus_tag="COSY_0070"
                     /note="Transketolase, C-terminal domain; Region:
                     Transketolase_C; pfam02780"
                     /db_xref="CDD:217227"
     gene            71501..72496
                     /gene="gapA"
                     /locus_tag="COSY_0071"
                     /db_xref="GeneID:5171949"
     CDS             71501..72496
                     /gene="gapA"
                     /locus_tag="COSY_0071"
                     /EC_number="1.2.1.12"
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="YP_001218931.1"
                     /db_xref="GI:148244237"
                     /db_xref="GeneID:5171949"
                     /translation="MAIKIGINGFGRIGRMVFRAIAKDFPELEVVGINDLLENNYLAY
                     MLKYDTAHGRFDDNITVDNNNLFINGKKIRLSAARDPANLLWGDIDVDVAIDCTGFFL
                     TKESCQSHIDAGAKKVVQSAPSKDDTPMFVYGVNHTKYSGQAIISAASCTTNCLAPIA
                     KVINDNWGLKRGLMTTIHASTATQKTVDSPSMKDWRGGRSVFENIIPSSTGAAKAVGV
                     VLPELNGKLTGMAFRIPSVDVSVVDLTCELNKSATYEQIFDAMKEASQGSMKGTLAYT
                     KDAVVSSDFRGFSASSIFDYDAGIALDDTFVKVVSWYDNEYGYTCNMLRLVECVA"
     misc_feature    71504..72493
                     /gene="gapA"
                     /locus_tag="COSY_0071"
                     /note="Glyceraldehyde-3-phosphate
                     dehydrogenase/erythrose-4-phosphate dehydrogenase
                     [Carbohydrate transport and metabolism]; Region: GapA;
                     COG0057"
                     /db_xref="CDD:223135"
     misc_feature    71507..71950
                     /gene="gapA"
                     /locus_tag="COSY_0071"
                     /note="Glyceraldehyde 3-phosphate dehydrogenase, NAD
                     binding domain; Region: Gp_dh_N; pfam00044"
                     /db_xref="CDD:215675"
     misc_feature    71966..72439
                     /gene="gapA"
                     /locus_tag="COSY_0071"
                     /note="Glyceraldehyde 3-phosphate dehydrogenase,
                     C-terminal domain; Region: Gp_dh_C; pfam02800"
                     /db_xref="CDD:217235"
     gene            72944..74122
                     /gene="pgk"
                     /locus_tag="COSY_0072"
                     /db_xref="GeneID:5172231"
     CDS             72944..74122
                     /gene="pgk"
                     /locus_tag="COSY_0072"
                     /EC_number="2.7.2.3"
                     /note="Converts 3-phospho-D-glycerate to
                     3-phospho-D-glyceroyl phosphate during the glycolysis
                     pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="YP_001218932.1"
                     /db_xref="GI:148244238"
                     /db_xref="GeneID:5172231"
                     /translation="MSVINLSDLDLNSKRVLIRQDLNVPISNGVVTSDKRIKASLPTI
                     KMALNQGAKVMLMSHRGRPIEGDPSDGFSLQPVADRLSELLNTTVRLEKDWLDGVEMN
                     NGKVVLCENVRFNVGEMVNDDELSKRMAAICDIFVMDAFGTAHRAQASTYGVAKYAPI
                     ACSGPLLSEELDALGKALDNPKRPMVAIVGGSKVSTKLTVLESLSKIVDQLVVGGGIA
                     NTFIAAQGFNVGKSLCEYDLIPIAKKLMEDCEIPVSKDVVCGKEFSDVAEAETKASKD
                     VADDDMIFDIGPKSAQQLADIMRNAGTIVWNGPVGVFEFDQFAGGTETLGKAIAESNA
                     FSIAGGGDTLAAVDKYGIEDKISYISTGGGAFLEFLEGKKLPAVEVLEQRALEVIKLA
                     "
     misc_feature    72956..74062
                     /gene="pgk"
                     /locus_tag="COSY_0072"
                     /note="Phosphoglycerate kinase; Region: PGK; pfam00162"
                     /db_xref="CDD:215761"
     misc_feature    72959..74092
                     /gene="pgk"
                     /locus_tag="COSY_0072"
                     /note="Phosphoglycerate kinase (PGK) is a monomeric enzyme
                     which catalyzes the transfer of the high-energy phosphate
                     group of 1,3-bisphosphoglycerate to ADP, forming ATP and
                     3-phosphoglycerate. This reaction represents the first of
                     the two substrate-level...; Region:
                     Phosphoglycerate_kinase; cd00318"
                     /db_xref="CDD:238195"
     misc_feature    order(73004..73006,73010..73012,73049..73051,73118..73120,
                     73280..73282)
                     /gene="pgk"
                     /locus_tag="COSY_0072"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238195"
     misc_feature    order(73475..73486,74018..74026)
                     /gene="pgk"
                     /locus_tag="COSY_0072"
                     /note="hinge regions; other site"
                     /db_xref="CDD:238195"
     misc_feature    order(73589..73591,73790..73792,73862..73864,73868..73870,
                     73874..73885,73964..73972)
                     /gene="pgk"
                     /locus_tag="COSY_0072"
                     /note="ADP binding site [chemical binding]; other site"
                     /db_xref="CDD:238195"
     misc_feature    73967..73969
                     /gene="pgk"
                     /locus_tag="COSY_0072"
                     /note="catalytic site [active]"
                     /db_xref="CDD:238195"
     gene            74115..75557
                     /locus_tag="COSY_0073"
                     /db_xref="GeneID:5171841"
     CDS             74115..75557
                     /locus_tag="COSY_0073"
                     /EC_number="2.7.1.40"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="YP_001218933.1"
                     /db_xref="GI:148244239"
                     /db_xref="GeneID:5171841"
                     /translation="MPRRTKILATLGPATDKYGVLVSILEAGVNVVRINFSHGSEKEH
                     LNRVKEVRAWAEANQTYVGVLMDLQGPKIRIAAFKGGIKIQLNNGDTFALDAGLDENL
                     GNKYSVGIAYKKLPQEVQPGSILLLDDGKIILKVIDIKGNKINTNVIQGGILSDKKGI
                     NLRGGGLSANALTKKDKKDILIVAKAKADYVALSFPVSGDDVREIKKLLKQVDCDAGV
                     ISKIERAESLVESVILDIIRESVGIMVARGDLGVEIGDAQLPAQQKRLIKLARSNNRI
                     VITATQMLESMIINPIPTRAEVFDVANAVLDGTDAVMLSAETAVGNFPGNAVKTMHDV
                     CIEAEKNPIAKISHHRLDETFTHIDETIAMSAMYAANHMGARVISTLTESGKTAIWMS
                     RISSGIPIVAMSDKISTLQKATLYRGVHPCFLSTKKDWTEINKAVIKRLQIGDFVYDG
                     DTVILTKGMYKNKSGGTNLMKILTVGDSEY"
     misc_feature    74115..75512
                     /locus_tag="COSY_0073"
                     /note="pyruvate kinase; Provisional; Region: PRK05826"
                     /db_xref="CDD:235619"
     misc_feature    74121..75539
                     /locus_tag="COSY_0073"
                     /note="Pyruvate kinase (PK):  Large allosteric enzyme that
                     regulates glycolysis through binding of the substrate,
                     phosphoenolpyruvate, and one or more allosteric effectors.
                     Like other allosteric enzymes, PK has a high substrate
                     affinity R state and a low...; Region: Pyruvate_Kinase;
                     cl17342"
                     /db_xref="CDD:247896"
     misc_feature    order(74124..74129,74295..74297,74301..74303,74325..74336,
                     74592..74597,74613..74615,74622..74636,74679..74681,
                     74703..74705,74724..74726,74757..74759,74871..74873,
                     74925..74930,74940..74942,75036..75038,75042..75044,
                     75129..75131,75135..75140,75291..75293,75297..75299,
                     75303..75305,75336..75338,75345..75350,75354..75356,
                     75360..75368)
                     /locus_tag="COSY_0073"
                     /note="domain interfaces; other site"
                     /db_xref="CDD:238178"
     misc_feature    order(74211..74213,74217..74219,74313..74315,74697..74699,
                     74775..74777,74781..74783,74859..74861,74955..74957)
                     /locus_tag="COSY_0073"
                     /note="active site"
                     /db_xref="CDD:238178"
     gene            75633..76694
                     /gene="fbaA"
                     /locus_tag="COSY_0074"
                     /db_xref="GeneID:5171988"
     CDS             75633..76694
                     /gene="fbaA"
                     /locus_tag="COSY_0074"
                     /EC_number="4.1.2.13"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase, class II"
                     /protein_id="YP_001218934.1"
                     /db_xref="GI:148244240"
                     /db_xref="GeneID:5171988"
                     /translation="MLISLRELLDHAAANNYGMPAFNVNNMEQVHAIMKAADKTNSPV
                     IMQGSAGARGYAGEPFLRHLILAAIEMYPHIPVVMHQDHGSDPSVCLRSIQSGFSSVM
                     MDGSLEPDMKTPASFKYNVNVTTEVVKIAHAGGVSVEGELGCLGSLETGMMGEEDGHG
                     AEGKLDLDMLLTSVEEAADFVKSTNVDALAIAIGTSHGAYKFTQEPTGDVLRIDRIKE
                     IHARIPNTHLVMHGSSSVPQDWLKIINNFGGDMGQTYGVPVEEIQEGIKHGVRKVNID
                     TDLRMSSTGAIRKHLGENTSNFDPRKFLKEATNAMSDICAARFEAFGSANNADKIIVS
                     SLDTMSKKYLSIELDSQVK"
     misc_feature    75645..76628
                     /gene="fbaA"
                     /locus_tag="COSY_0074"
                     /note="fructose-bisphosphate aldolase; Provisional;
                     Region: PRK09197"
                     /db_xref="CDD:236406"
     misc_feature    75645..76610
                     /gene="fbaA"
                     /locus_tag="COSY_0074"
                     /note="Tagatose-1,6-bisphosphate (TBP) aldolase and
                     related Type B Class II aldolases. TBP aldolase is a
                     tetrameric class II aldolase that catalyzes the reversible
                     condensation of dihydroxyacetone phosphate with
                     glyceraldehyde 3-phsophate to produce tagatose 1; Region:
                     TBP_aldolase_IIB; cd00947"
                     /db_xref="CDD:238477"
     misc_feature    order(75708..75716,75723..75725,75783..75785,75792..75800,
                     75810..75812,75822..75824,75831..75836,76098..76100,
                     76461..76466,76470..76475,76482..76484,76494..76496,
                     76503..76505)
                     /gene="fbaA"
                     /locus_tag="COSY_0074"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238477"
     misc_feature    order(75876..75881,76218..76226,76230..76232,76323..76328,
                     76332..76334,76452..76454,76458..76463)
                     /gene="fbaA"
                     /locus_tag="COSY_0074"
                     /note="active site"
                     /db_xref="CDD:238477"
     misc_feature    order(75879..75881,76221..76223,76323..76325)
                     /gene="fbaA"
                     /locus_tag="COSY_0074"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:238477"
     misc_feature    order(76218..76220,76224..76226,76230..76232,76326..76328,
                     76332..76334)
                     /gene="fbaA"
                     /locus_tag="COSY_0074"
                     /note="Na+ binding site [ion binding]; other site"
                     /db_xref="CDD:238477"
     gene            76761..78626
                     /gene="gidA"
                     /locus_tag="COSY_0075"
                     /db_xref="GeneID:5172042"
     CDS             76761..78626
                     /gene="gidA"
                     /locus_tag="COSY_0075"
                     /note="GidA; glucose-inhibited cell division protein A;
                     involved in the 5-carboxymethylaminomethyl modification
                     (mnm(5)s(2)U) of the wobble uridine base in some tRNAs"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-carboxymethylaminomethyl
                     modification enzyme GidA"
                     /protein_id="YP_001218935.1"
                     /db_xref="GI:148244241"
                     /db_xref="GeneID:5172042"
                     /translation="MKQSKRYLVIVIGGGHAGTEAALASARMGVSTLLISHNIETLGQ
                     MSCNPAIGGIGKGHLVKEIDAMGGIMAHTIDKSGIQFRTLNASKGSAVRATRAQADRI
                     LYKSEIRYALENQDNLSLFQQSVDDLIIKGDQIKGVVTQMGLALMADKVILTSGTFLG
                     GIIHIGQRNFQGGRAGDAPSNALSRKLRSYDLGVNRLKTGTPPRLDGRTLDYSLMQVQ
                     SGDIPLPTFSFIGVKEEHPRQIPCYITHTNKRTHDLIRSGLKDSPIFTGNIESIGPRY
                     CPSIEDKVVRFNERDSHQIFVEPEGLSTNEVYPNGVSTSLSYKVQLDFINSIKGFENA
                     QIIRPGYAIEYDFFDPRGLKQTLEVKKISGLYFAGQINGTTGYEEAAAQGLLAGVNAA
                     CAILEKDAWLPKRDESYIGVMVDDLITKGTNEPYRMFTSRAEYRLLLREDNADERLTP
                     KAKELGLISEARWQSFQVKYNAVEQEKKRLKNTWIQANDTQANTILNQNISHEYSLFE
                     LLKRPKVDYQILSKIESGKPFLTDITLMRVIENQIKYAGYIKRQLVEIEKYRKNENTV
                     LSTNINYNSIKALSTEVRQKLELHKPETIGQASRIQGVTPASISILLVYLKTRIS"
     misc_feature    76773..78617
                     /gene="gidA"
                     /locus_tag="COSY_0075"
                     /note="tRNA uridine 5-carboxymethylaminomethyl
                     modification enzyme GidA; Validated; Region: PRK05192"
                     /db_xref="CDD:235362"
     misc_feature    76785..>77144
                     /gene="gidA"
                     /locus_tag="COSY_0075"
                     /note="tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO;
                     TIGR00137"
                     /db_xref="CDD:129243"
     misc_feature    <77691..78023
                     /gene="gidA"
                     /locus_tag="COSY_0075"
                     /note="NAD(FAD)-utilizing enzyme possibly involved in
                     translation [Translation, ribosomal structure and
                     biogenesis]; Region: Gid; COG1206"
                     /db_xref="CDD:224127"
     misc_feature    78387..78602
                     /gene="gidA"
                     /locus_tag="COSY_0075"
                     /note="GidA associated domain 3; Region: GIDA_assoc_3;
                     pfam13932"
                     /db_xref="CDD:206103"
     gene            78995..79795
                     /locus_tag="COSY_0076"
                     /db_xref="GeneID:5172060"
     CDS             78995..79795
                     /locus_tag="COSY_0076"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218936.1"
                     /db_xref="GI:148244242"
                     /db_xref="GeneID:5172060"
                     /translation="MKKIGYFLIGLIVILVLIMMLVFDSIGKKYVQKYAQNILRTPIT
                     ISQFSSSFWDKRLNIDFIEVQNPPNFNNKDAFYLDHFVLKIGDDTTLDLIVIDELSFD
                     GMHFILEQNKTNVNLVTLIDNLGKSSNNTTLSSSEETHGVIDKRIKINQFNVINTTLK
                     IDTKWLKETIKVPNINLQKFGGNSGITLNKVGQELMEIVLNNLEDALEKKGIELGEKE
                     IKETLIQRLWINNIQENFKLDKFKESLDFSETKKLQNQAKDLFQKLGF"
     gene            79802..80572
                     /gene="tatD"
                     /locus_tag="COSY_0077"
                     /db_xref="GeneID:5172312"
     CDS             79802..80572
                     /gene="tatD"
                     /locus_tag="COSY_0077"
                     /note="TatD-related deoxyribonuclease"
                     /codon_start=1
                     /transl_table=11
                     /product="Mg-dependent deoxyribonuclease"
                     /protein_id="YP_001218937.1"
                     /db_xref="GI:148244243"
                     /db_xref="GeneID:5172312"
                     /translation="MQIVDSHCHLDKLDFVNFGGNIESVIAHAKELSVVKFLCVCIDL
                     EHFDEILFLAKKYPQIYASVGVHPVNTKGKDPSICQLLKLANYEEVIAIGETGLDYFH
                     IEKSIADWQQNRFRRHIRASNQSGKPMIIHTRNAKEDTIKIMQEEKAKQGVMHCFSED
                     WETAQMALDLGFYISFSGIITFKSAKDLREVAKKVPSDKLLVETDSPYLTPMPYRGTS
                     NLPAYSYYVAEKLAEIRGVSINDIANTTTNNFEQLFLT"
     misc_feature    79808..80563
                     /gene="tatD"
                     /locus_tag="COSY_0077"
                     /note="TatD like proteins;  E.coli TatD is a cytoplasmic
                     protein, shown to have magnesium dependent DNase activity;
                     Region: TatD_DNAse; cd01310"
                     /db_xref="CDD:238635"
     misc_feature    79811..80563
                     /gene="tatD"
                     /locus_tag="COSY_0077"
                     /note="Predicted metal-dependent hydrolases with the
                     TIM-barrel fold [General function prediction only];
                     Region: COG1099"
                     /db_xref="CDD:224024"
     misc_feature    order(79820..79822,79826..79828,80195..80197,80264..80266,
                     80414..80416)
                     /gene="tatD"
                     /locus_tag="COSY_0077"
                     /note="active site"
                     /db_xref="CDD:238635"
     gene            80569..81480
                     /gene="rluC"
                     /locus_tag="COSY_0078"
                     /db_xref="GeneID:5172248"
     CDS             80569..81480
                     /gene="rluC"
                     /locus_tag="COSY_0078"
                     /EC_number="4.2.1.70"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal large subunit pseudouridine synthase
                     C"
                     /protein_id="YP_001218938.1"
                     /db_xref="GI:148244244"
                     /db_xref="GeneID:5172248"
                     /translation="MSVSFQTIDEFSQGQRLDNYLLKILKGVPKSHIYRVIRKGEVRV
                     NKGRKKSEYKLNLDDIVRIPPIKVSTTKSMYTSDGLKKILTNAILYEDKGLLIINKPS
                     GLAVHSGSGVNVGVIEALRQMYKEPIELVHRLDRATSGVLLVAKKRLVLKNLHEQLNQ
                     HTIEKHYIALVKGVWSKKIHTINAPLYNNSRYTKVDAKGKYSVSHFHPLKNFNIENFS
                     ASLVNISIETGRTHQIRVHAKYVGHALACDNKYGDKEFDRQVKFKGLKRLFLHSNQLI
                     FINPLTNDIQKVNAPLPIELEEFLAKL"
     misc_feature    80572..81477
                     /gene="rluC"
                     /locus_tag="COSY_0078"
                     /note="23S rRNA pseudouridylate synthase C; Provisional;
                     Region: PRK11025"
                     /db_xref="CDD:182909"
     misc_feature    80611..80865
                     /gene="rluC"
                     /locus_tag="COSY_0078"
                     /note="S4/Hsp/ tRNA synthetase RNA-binding domain; The
                     domain surface is populated by conserved, charged residues
                     that define a likely RNA-binding site;  Found in stress
                     proteins, ribosomal proteins and tRNA synthetases; This
                     may imply a hitherto unrecognized...; Region: S4; cd00165"
                     /db_xref="CDD:238095"
     misc_feature    order(80614..80616,80650..80655,80659..80664,80668..80673,
                     80680..80685,80689..80691,80710..80712,80713..80730,
                     80734..80736)
                     /gene="rluC"
                     /locus_tag="COSY_0078"
                     /note="RNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238095"
     misc_feature    80851..81399
                     /gene="rluC"
                     /locus_tag="COSY_0078"
                     /note="Pseudouridine synthase, RsuA/RluD family; Region:
                     PseudoU_synth_RluCD_like; cd02869"
                     /db_xref="CDD:211346"
     misc_feature    order(80962..80973,81271..81273)
                     /gene="rluC"
                     /locus_tag="COSY_0078"
                     /note="active site"
                     /db_xref="CDD:211346"
     gene            81477..82346
                     /gene="ubiA"
                     /locus_tag="COSY_0079"
                     /db_xref="GeneID:5172678"
     CDS             81477..82346
                     /gene="ubiA"
                     /locus_tag="COSY_0079"
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="YP_001218939.1"
                     /db_xref="GI:148244245"
                     /db_xref="GeneID:5172678"
                     /translation="MNFHFKTTSFVAYLRLMRLDNPIGIYLLLWPTLWALFLASEGFP
                     DLKLLLIFVLGVVLMRSAGCVINDYADRYIDKLVERTKHRPITSGEIHHRSALKFFVL
                     LIMLAFLLVLLTNWLTIQLAMIAVLLAILYPFTKRWTYFPQFVLGLAFAMSVLMAFSA
                     TLNEIPITAWYVFAATVIWTVIYDTMYAMADREEDLKIGIKSSAILFAKFDRLIIGIL
                     QIIFLLILIKISNVFNLTISYHITLLLVTLLMIYHQYLIKNNENYSYLHGFLHNNYIG
                     MVIFIGIVLSVGL"
     misc_feature    81510..82334
                     /gene="ubiA"
                     /locus_tag="COSY_0079"
                     /note="4-hydroxybenzoate polyprenyltransferase and related
                     prenyltransferases [Coenzyme metabolism]; Region: UbiA;
                     cl00337"
                     /db_xref="CDD:241797"
     misc_feature    81600..>82103
                     /gene="ubiA"
                     /locus_tag="COSY_0079"
                     /note="UbiA prenyltransferase family; Region: UbiA;
                     pfam01040"
                     /db_xref="CDD:216260"
     gene            complement(82865..83680)
                     /gene="dapD"
                     /locus_tag="COSY_0080"
                     /db_xref="GeneID:5171864"
     CDS             complement(82865..83680)
                     /gene="dapD"
                     /locus_tag="COSY_0080"
                     /EC_number="2.3.1.117"
                     /note="catalyzes the formation of
                     N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and
                     tetrahydrodipicolinate in the lysine biosynthetic pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-carboxylate
                     N-succinyltransferase"
                     /protein_id="YP_001218940.1"
                     /db_xref="GI:148244246"
                     /db_xref="GeneID:5171864"
                     /translation="MKDIIEKAFEDRANLNPQTVNVKVKQAVTDAIHLLDSGKARIAQ
                     QKSIGNWKVNEWLKKAVLLSFRLEENIPMQGGFTQYFDKVPSKFADMSINEFNKAGIR
                     IVPPASARYGSFIAKNTVMMPSYVNIGAYVDSGTMIDTWATVGSCAQIGKNVHLSGGV
                     GIGGVLEPLQASPTIIEDNCFIGARSEIVEGVIIEESAVISMGVYIGQSTKIFNRKTN
                     KITYGRIPAGSVVVPGNLPSKDGTYSLYCAVIVKQVDAKTRYKIGINELLRGI"
     misc_feature    complement(82874..83680)
                     /gene="dapD"
                     /locus_tag="COSY_0080"
                     /note="2,3,4,5-tetrahydropyridine-2,6-carboxylate
                     N-succinyltransferase; Provisional; Region: dapD;
                     PRK11830"
                     /db_xref="CDD:236996"
     misc_feature    complement(82970..83383)
                     /gene="dapD"
                     /locus_tag="COSY_0080"
                     /note="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP)
                     N-succinyltransferase (also called THP
                     succinyltransferase): THDP N-succinyltransferase catalyzes
                     the conversion of tetrahydrodipicolinate and succinyl-CoA
                     to N-succinyltetrahydrodipicolinate and CoA; Region:
                     LbH_THP_succinylT; cd03350"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(82970..82972,82976..82987,83066..83068,
                     83120..83122,83126..83128,83204..83206,83252..83260,
                     83306..83308,83312..83314,83360..83365,83372..83377))
                     /gene="dapD"
                     /locus_tag="COSY_0080"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(83075..83080,83111..83113,83126..83134,
                     83171..83173,83180..83185,83189..83191,83210..83212,
                     83216..83218,83243..83245,83264..83266,83300..83302,
                     83318..83320,83351..83353,83375..83377))
                     /gene="dapD"
                     /locus_tag="COSY_0080"
                     /note="active site"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(83183..83185,83243..83245,83264..83266,
                     83300..83302,83318..83320,83351..83353,83375..83377))
                     /gene="dapD"
                     /locus_tag="COSY_0080"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100041"
     misc_feature    complement(order(83075..83080,83111..83113,83126..83134,
                     83171..83173,83189..83191,83207..83212))
                     /gene="dapD"
                     /locus_tag="COSY_0080"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:100041"
     gene            83842..85236
                     /locus_tag="COSY_0081"
                     /db_xref="GeneID:5172181"
     CDS             83842..85236
                     /locus_tag="COSY_0081"
                     /note="Similar to nitrogen fixation protein FixG in
                     Brucella suis 1330."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="YP_001218941.1"
                     /db_xref="GI:148244247"
                     /db_xref="GeneID:5172181"
                     /translation="MTDKKIQIENLYEEGELWVQNLGDKTIHAKRMKGKFRNLKWLAI
                     FVWLPFFMGPYLTWDDKQAILFDIDNRQYHLFNITIFPQDIWMLTMVLLFLSILLAIM
                     TAILGRIFCGYFCFQTIWTDIFTKIEQWIEGTPVQRRKLDKEPMSFNKFRLKLVKHSI
                     WIAIALFSGITWMLYFGVTWTNYVKGDVTSTTMVITAIISFGAYVFAGFMREQTCLWI
                     CPYARIQGAMVDEQSILPTYDYYRGERRGRLKKGKFVKGFGDCVDCHQCVAVCPTGVD
                     IRKGQEYGCITCGLCIDACDLVMEKVGKPKGLICYTSLAEMKFNKPVKVFYKRPRVII
                     YASVLFLALSILVYGILNLAPMDLKVLHDRQPLFVQLSDGSIRNKYELKVMNKTNKIM
                     PISISFSSKIKNLKSKKSFKTVMIPSGNVKSIYVYLIALESDVGSDNNVIFVVKSEQV
                     TLEYKTLFFTPKSI"
     misc_feature    83947..85218
                     /locus_tag="COSY_0081"
                     /note="cytochrome c oxidase accessory protein FixG;
                     Region: ccoG_rdxA_fixG; TIGR02745"
                     /db_xref="CDD:233993"
     misc_feature    84103..84246
                     /locus_tag="COSY_0081"
                     /note="4Fe-4S binding domain; Region: Fer4_5; pfam12801"
                     /db_xref="CDD:221777"
     misc_feature    84877..85224
                     /locus_tag="COSY_0081"
                     /note="Ubp3 associated protein Bre5; Region: Bre5;
                     pfam11614"
                     /db_xref="CDD:221151"
     gene            85236..85715
                     /locus_tag="COSY_0082"
                     /db_xref="GeneID:5172383"
     CDS             85236..85715
                     /locus_tag="COSY_0082"
                     /note="Similar to nitrogen fixation protein FixH in
                     Brucella suis 1330."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218942.1"
                     /db_xref="GI:148244248"
                     /db_xref="GeneID:5172383"
                     /translation="MSIHRSPIMMVMLMLFIILVGATVYRIIIALETHPGLVVEDAYS
                     SGQRYAITLNHKNQLAQLGWALNLVTPEAVSHNIKQIYTVNSTQHGKALSDALVTAYF
                     YRPLEKVHDFSINMLFRQGIDKYQAYIILPLKGRWDLVVEVVKEGLVQRVSKKLFAQ"
     misc_feature    85296..85706
                     /locus_tag="COSY_0082"
                     /note="FixH; Region: FixH; pfam05751"
                     /db_xref="CDD:218730"
     misc_feature    85422..85661
                     /locus_tag="COSY_0082"
                     /note="YtkA-like; Region: YtkA; pfam13115"
                     /db_xref="CDD:221926"
     gene            complement(86107..86826)
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /db_xref="GeneID:5172387"
     CDS             complement(86107..86826)
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein"
                     /protein_id="YP_001218943.1"
                     /db_xref="GI:148244249"
                     /db_xref="GeneID:5172387"
                     /translation="MSEILISANHISLSHHGKKVLDDVNFELKIGEFITLIGPNGAGK
                     SSLIKILLGLITPDNGKIKKSKHIRLSYTPQKFIPNEFIPISVIDFLKLNQKIDAKFL
                     KDTTTLTGIETLLHLALKNLSGGEIQRVLLTRALLAKPNVLILDEPTQNLDVSGQMHL
                     YKLIQDIHKQQNCAVLMVSHDLHRVMKESTQVLCLYHHICCIGKPYTILKDAQFNNLF
                     ADQIDELMATYEHHHNHEHKY"
     misc_feature    complement(86116..86814)
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /note="high-affinity zinc transporter ATPase; Reviewed;
                     Region: znuC; PRK09544"
                     /db_xref="CDD:181939"
     misc_feature    complement(86218..86808)
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    complement(86692..86715)
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(86287..86289,86386..86391,86602..86604,
                     86689..86697,86701..86706))
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(86602..86613)
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(86434..86463)
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(86386..86403)
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(86368..86379)
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(86281..86301)
                     /gene="znuC"
                     /locus_tag="COSY_0083"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            86918..89647
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /db_xref="GeneID:5172735"
     CDS             86918..89647
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /EC_number="2.7.7.7"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="YP_001218944.1"
                     /db_xref="GI:148244250"
                     /db_xref="GeneID:5172735"
                     /translation="MPHKLILMDGSAFLFRAYFSTLKQNLTNQNGFPTGAMFGVINAM
                     KSLQRKYQEARIIIIFDARGKNFRHNIYPQYKANRKPIDGGLVVQIEPLYEMIQAMGI
                     HFICVSKVEADDVIATLSCCANQNNIKTIIASGDKDLMQLVGTNISQLNMKGVLHDRQ
                     SVIEKIGVAPEKILDFLALTGDSADNIPGVPSVGPKTAIKWLQIYSDILGIKENAMQI
                     KGKVGEKLRDNFDLLDLSYQLVKLKFDVVLPCNILDDEPVKNIDKLANLYQQYGFFMW
                     LKQLDNVSVLKQKSIQVIGTDTGVNNSVDILKGYSQILVLDLDIFNTMVSRLKILKTF
                     VFSLKATSLDYMNASIVGWVFLIDKDSFYVPVNHDYIDAPKQLNFNDVLNQLKPILED
                     VSISKIGQNLKYDAHILSNYKIDLQGISDDVIVKSYCLNSVATRHNMNDLSEYYLNYQ
                     TINFVDILGKGKKQVTFNQVNVEIALLYVCENVIITSLLNHMLDEEIAQYPRLVKLYQ
                     NLELPLIKVLLCMERNGVELDVNILSTQQLDITQQMEDIKNQVFELADNVFNLESPKQ
                     IQRILFESKGLGLIPLRKTPKGVPSTNEEALKLLDHPVVDLILSYRTLAKLNSTYLEV
                     LPRKIDLNTHRLHTSYNQVVTATGRLSSSNPNLQNIPIFSEQGSCIRGAFITGKGNVI
                     ISADYSQIELRIMTQLSKDQNLLEAFNNDKDVHSETASTMFNIPIDEVTSEYRRRAKA
                     INFGLIYGMSAYGLAKQIGVSRTKAKQYMDTYFDNYPSVLYYMDNIKEIAKVQGYVET
                     IMGRRLYLPQINAKNKMLQQHALRTAINAPMQGSSADIIKKSMFDVYTWIGQDNPDIR
                     MIMQVHDELVFEVSASKADEFSRKIQALMSNTYLLDIPLKVDVGIGNSWKEAH"
     misc_feature    86927..89644
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="DNA polymerase I; Provisional; Region: PRK05755"
                     /db_xref="CDD:235591"
     misc_feature    86930..87415
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="PIN domain of the 5&apos;-3&apos; exonuclease of
                     Taq DNA polymerase I and homologs; Region: PIN_53EXO;
                     cd09859"
                     /db_xref="CDD:189029"
     misc_feature    order(86942..86944,87098..87100,87248..87250,87254..87259,
                     87323..87325,87329..87331)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="active site"
                     /db_xref="CDD:189029"
     misc_feature    order(86942..86944,87254..87256,87323..87325)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="metal binding site 1 [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:189029"
     misc_feature    87116..87154
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="putative 5' ssDNA interaction site; other site"
                     /db_xref="CDD:189029"
     misc_feature    order(87248..87250,87257..87259)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="metal binding site 3; metal-binding site"
                     /db_xref="CDD:189029"
     misc_feature    order(87323..87325,87329..87331)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="metal binding site 2 [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:189029"
     misc_feature    87425..87643
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="H3TH domain of the 5&apos;-3&apos; exonuclease of
                     Taq DNA polymerase I and homologs; Region: H3TH_53EXO;
                     cd09898"
                     /db_xref="CDD:188618"
     misc_feature    order(87455..87478,87482..87511,87515..87526)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:188618"
     misc_feature    order(87461..87463,87470..87472)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:188618"
     misc_feature    87896..88471
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="DEDDy 3&apos;-5&apos; exonuclease domain of
                     Escherichia coli DNA polymerase I and similar bacterial
                     family-A DNA polymerases; Region:
                     DNA_polA_I_Ecoli_like_exo; cd06139"
                     /db_xref="CDD:176651"
     misc_feature    order(87926..87937,87944..87946,88115..88120,88124..88132,
                     88229..88234,88277..88282,88349..88351,88361..88363)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="active site"
                     /db_xref="CDD:176651"
     misc_feature    order(87926..87928,87932..87934,88130..88132,88349..88351,
                     88361..88363)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="catalytic site [active]"
                     /db_xref="CDD:176651"
     misc_feature    order(87929..87937,87944..87946,88115..88120,88124..88129,
                     88229..88234,88277..88282,88349..88351,88361..88363)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:176651"
     misc_feature    88502..89632
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="Polymerase I functions primarily to fill DNA gaps
                     that arise during DNA repair, recombination and
                     replication; Region: DNA_pol_A_pol_I_C; cd08637"
                     /db_xref="CDD:176474"
     misc_feature    order(88751..88753,88763..88765,88772..88777,88850..88858,
                     88862..88864,88868..88879,88973..88978,89060..89062,
                     89120..89122,89132..89134,89384..89386,89405..89407,
                     89498..89506)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="active site"
                     /db_xref="CDD:176474"
     misc_feature    order(88751..88753,88763..88765,88772..88777,88850..88858,
                     88862..88864,88868..88879,89156..89158,89381..89386,
                     89393..89395,89405..89407,89498..89506)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:176474"
     misc_feature    order(88973..88978,88982..88984,89060..89062,89120..89122,
                     89132..89134,89504..89506)
                     /gene="polA"
                     /locus_tag="COSY_0084"
                     /note="catalytic site [active]"
                     /db_xref="CDD:176474"
     gene            90504..92222
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /db_xref="GeneID:5172418"
     CDS             90504..92222
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /EC_number="6.1.1.19"
                     /note="catalyzes a two-step reaction, first charging an
                     arginine molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA
                     synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="arginyl-tRNA synthetase"
                     /protein_id="YP_001218945.1"
                     /db_xref="GI:148244251"
                     /db_xref="GeneID:5172418"
                     /translation="MKQLLQQLLVQSLEVLMDNNILESMPENIRVDHSKDKAQGDFAS
                     NIAMLLSEQAQCSSKVLAQKIKANFPDSVDVEKIEIVGPGFINFFMSQSSNALVVEDI
                     IKQGGNYGLSNIGMGQRVLLEFVSANPTGPLHVGHGRGVAYGAAVAHLLRAVGFEVDC
                     EYYVNDAGRQMDILAISVYLRYVETEQFPDNCYKGDYIFDIAKKISGVKKLDIFTNTC
                     KDTSEWKVQKNSIDKERYIDDLIANCKLQLGSDYRKVFDFAINSILSDIKIDLADFGV
                     EYHQWFSEQSLVDSGLSEEIVKKLQDLGYIYEKEGALWFRTTDFGDDLDRVVVRDNGI
                     HTYFSYDIAYHLGKFERGYDRIINIWGADHHGYIARVKASIKALNYNPDKLEILLVQF
                     VNLFRDGKKVSMSTRSGSFITLKELREEVGNDVVRFFYILRKSTQHMDFNLDLAKSKS
                     NENPVFYIQYAYVRICSVLKQGMPFMADIDLLVLNNELETLLIKELNRYKDILQSSAL
                     NYEPHVLACYLRKLAGYFHSYYNNCEFLVDDDKLRNSRLLLITAVQQILANGLNLLGI
                     STPNSM"
     misc_feature    90567..92219
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="Arginyl-tRNA synthetase [Translation, ribosomal
                     structure and biogenesis]; Region: ArgS; COG0018"
                     /db_xref="CDD:223097"
     misc_feature    90570..90773
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="Arginyl tRNA synthetase N terminal dom; Region:
                     Arg_tRNA_synt_N; smart01016"
                     /db_xref="CDD:214975"
     misc_feature    90870..>91013
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="nucleotidyl transferase superfamily; Region:
                     nt_trans; cl00015"
                     /db_xref="CDD:241550"
     misc_feature    90903..90914
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="active site"
                     /db_xref="CDD:173912"
     misc_feature    90903..90914
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173912"
     misc_feature    order(90903..90905,90912..90914)
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173912"
     misc_feature    91194..91730
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="catalytic core domain of arginyl-tRNA synthetases;
                     Region: ArgRS_core; cd00671"
                     /db_xref="CDD:185675"
     misc_feature    91713..91724
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="KMSK motif region; other site"
                     /db_xref="CDD:185675"
     misc_feature    91758..92219
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="Anticodon-binding domain of class Ia aminoacyl tRNA
                     synthetases and similar domains; Region:
                     Anticodon_Ia_like; cl12020"
                     /db_xref="CDD:245839"
     misc_feature    order(91833..91835,91845..91847,91854..91856,91881..91883,
                     91893..91898,91902..91907,92052..92054,92073..92075,
                     92082..92084,92091..92093)
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="tRNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:153408"
     misc_feature    order(91881..91883,91890..91895,91902..91907,92091..92093)
                     /gene="argS"
                     /locus_tag="COSY_0085"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:153408"
     gene            92219..95389
                     /locus_tag="COSY_0086"
                     /db_xref="GeneID:5172170"
     CDS             92219..95389
                     /locus_tag="COSY_0086"
                     /EC_number="3.6.1.-"
                     /note="UvrD/Rep helicase family"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="YP_001218946.1"
                     /db_xref="GI:148244252"
                     /db_xref="GeneID:5172170"
                     /translation="MNDQKQRRQALDVSQSFIIQAPAGSGKTELLTQRYLKLLSVSTS
                     PESVIVMTFTKKAVSELTTRVIESLELAQGNRPKDPHKQIIYDLAFQVLERSKELDWQ
                     LLNTPERFKILTIDSLSSLITSHYPSKNQLVPKKVISQNWARYSMYSQAAKQTLLAIN
                     ELEYQDSVESILLYLDNNIDRFYQLITDMLAKRDQWILKLYQHGTLNIETLRLSSEKV
                     IIQHLSLLKNEVEYYFDPIFFKLLKYNSKLEFAQIKDVPDATIKSLEVWKNLSRLCLT
                     VQGKWRSSLNKNNGFPAELKMQKLAIIKIFQSLSSHQQLRELLAGVEYLPDINFSTDQ
                     INVLQDIAQVLKLAVSQLKILFDVNQTHDFIQVSLDADQALDEYHVSDIALFLDNKIQ
                     HILIDEFQDTSVIQFSLLEKLIANWYSGDGKTLFLVGDPMQSIYLFRQSQVGLFLQVR
                     TRGIANIKPEFLQLHTNFRSSQSVVEGNNEIFSKIFPNQEEAYKGAIKYEYSKAYFTA
                     ESKRAINFYPFAYKRYDFEAQQVLKIIQNNPTKEIAILVRNRSHLNNIVPVLKQANIN
                     FEAVKILPLKDDLFTRDLLSLTRALIYLGDKLAWLAILRAPWCGLLLEDLLVLSQNNE
                     RVIFDLIRDDQTLQGLSSDGRIRVDNFAYVLGNIVNQQSRFSFTQVLEFAINQLVPPN
                     SLSVKQSMIKTQFLQIIYDCEFEQQLDIETINKMLDELYTPSVNVLNARIKLMTIHEA
                     KGLEFELVIIPGLGRVSQNNKSPIIHLQEFSNQSLLLAPIRSYTQLNDSCTYVYLKHI
                     KSQQDRFETMRLLYVAMTRAKYKIYLLATLSQSNQAIRNTFLKLLEPIFQNRFDQLKS
                     SVIEDNKQPIRAPELVRYIKPIEYNNLLDRSKKKMNFQLNVDLQYKSLLGILLHQYYA
                     NELFSPDRQNIRVRLVEFGISNMDIDDSIDFIIDMLNLTKQDKYFSWLFKQRVSTQVE
                     VEFINDKRNIIIDRLFIDEGILWVIDFKTERQVNNESIVQFIQRQKIKHSHQLLFYKV
                     TLSECYSMEVKCALYCPSVQKLIRID"
     misc_feature    92267..>92413
                     /locus_tag="COSY_0086"
                     /note="Part of AAA domain; Region: AAA_19; pfam13245"
                     /db_xref="CDD:222005"
     misc_feature    93608..94705
                     /locus_tag="COSY_0086"
                     /note="UvrD-like helicase C-terminal domain; Region:
                     UvrD_C; pfam13361"
                     /db_xref="CDD:222073"
     gene            complement(96260..96841)
                     /gene="thiE"
                     /locus_tag="COSY_0087"
                     /db_xref="GeneID:5172287"
     CDS             complement(96260..96841)
                     /gene="thiE"
                     /locus_tag="COSY_0087"
                     /EC_number="2.5.1.3"
                     /note="thiamine monophosphate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate pyrophosphorylase"
                     /protein_id="YP_001218947.1"
                     /db_xref="GI:148244253"
                     /db_xref="GeneID:5172287"
                     /translation="MVFNKKISHIYAITPDVSLNSILIRWVINKHHISILQYRHKTNN
                     NNMKLKEAYVLRQLCLVHNTLFIINDDINLTEKVHADGVHLGKDDGSIQQARQQLGID
                     SIIGISCYNDINLAFQAQKQGANYVTFGALFDSKTKPNAPHCPLNVITKAKQILHIPI
                     VGIGGIDLYNQQQAFDAGCDAVAMINALFKNYN"
     misc_feature    complement(96269..96814)
                     /gene="thiE"
                     /locus_tag="COSY_0087"
                     /note="Thiamine monophosphate synthase (TMP
                     synthase)/TenI. TMP synthase catalyzes an important step
                     in the thiamine biosynthesis pathway, the substitution of
                     the pyrophosphate of 2-methyl-4-amino-5-
                     hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-;
                     Region: TMP_TenI; cd00564"
                     /db_xref="CDD:238317"
     misc_feature    complement(order(96284..96295,96347..96349,96359..96361,
                     96431..96433,96437..96439,96458..96460,96464..96466,
                     96518..96520,96590..96592,96725..96727,96731..96733,
                     96803..96805,96809..96811))
                     /gene="thiE"
                     /locus_tag="COSY_0087"
                     /note="thiamine phosphate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238317"
     misc_feature    complement(order(96284..96289,96347..96349,96428..96433,
                     96437..96439,96518..96520,96575..96577,96632..96637,
                     96719..96721,96725..96727,96731..96733))
                     /gene="thiE"
                     /locus_tag="COSY_0087"
                     /note="active site"
                     /db_xref="CDD:238317"
     misc_feature    complement(order(96428..96430,96518..96520,96575..96577,
                     96584..96586,96632..96637,96719..96721,96725..96727))
                     /gene="thiE"
                     /locus_tag="COSY_0087"
                     /note="pyrophosphate binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238317"
     gene            96753..97796
                     /locus_tag="COSY_0088"
                     /db_xref="GeneID:5172704"
     CDS             96753..97796
                     /locus_tag="COSY_0088"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218948.1"
                     /db_xref="GI:148244254"
                     /db_xref="GeneID:5172704"
                     /translation="MLMTHLIRIELSETSGVIAYIWLIFLLNTMFDSQLRHSLLSVVF
                     IIVIIGIIWFFIGLFLFSCSVQEDKQKPLLIDNQTSFEGVTYLERIDNFSLQVFDIKA
                     ELSYFVKAKSYFSFKNLPVLLIEPKVTFYDAKGIKNYVLNSKRAHYVDNNGIKFKGEV
                     GIHFSNGFNHKINTEELLVGIETRDLMSKKQVTYLGETVKIISQGIQIRSKDDIIKLI
                     GNIKINQRDGQQILTKDLYINQIEGQKHFYSKNKIVYMFQKDKIYADSIDINEQKQII
                     ELLGKVKIMKDSGSKISTKNLFIDQSNGLEIYRTKEKVHYQSNTADIHAVGMIYDVIK
                     QKIKLTSDVIGIL"
     misc_feature    97020..97418
                     /locus_tag="COSY_0088"
                     /note="Lipopolysaccharide-assembly, LptC-related; Region:
                     LptC; pfam06835"
                     /db_xref="CDD:219198"
     misc_feature    <97461..97787
                     /locus_tag="COSY_0088"
                     /note="Lipopolysaccharide-assembly, LptC-related; Region:
                     LptC; pfam06835"
                     /db_xref="CDD:219198"
     gene            98093..99301
                     /gene="sat"
                     /locus_tag="COSY_0089"
                     /db_xref="GeneID:5172354"
     CDS             98093..99301
                     /gene="sat"
                     /locus_tag="COSY_0089"
                     /EC_number="2.7.7.4"
                     /note="ATP sulfurylase; ATPS; converts ATP and sulfate to
                     5'phosphosulfate and pyrophosphate; in some organisms this
                     enzyme is involved in the incorporation of inorganic
                     sulfate while in others it is involved in the production
                     of ATP in the reverse direction; the enzyme from Thermus
                     thermophilus is dimeric and binds a zinc ion that is
                     coordinated by cysteine and histidine residues that are
                     not found in all related proteins but is found in some
                     thermophilic organisms"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase"
                     /protein_id="YP_001218949.1"
                     /db_xref="GI:148244255"
                     /db_xref="GeneID:5172354"
                     /translation="MSKLVPPHGGDKLKPLALEGNSLMAELEKAKLLLKVSCSSREVG
                     DIIMMGIGGFTPLEGFMDNVNWQSVCDNMTMSSGLFWPIPITLSTNSEDIKQGDEVAL
                     VNGETDDIIATMVVSEKYSIDKSHECNTVYRTTEMAHPGVVMVMAQGKYNLAGSIKVL
                     SDGNFPEKYGSLYMTPMETRAYFDDKGWKTIAAFQTRNPMHRSHEYLAKIAVEICDGV
                     MIHSVLGGLKDGDIPADVRSEAISVLIKNYFVDNTILQSGYPLDMRYAGPREALLHAL
                     FRQNYGCSHLIVGRDHAGVNDYYGPFDAHNIFNVIANDALVTKALKFDWTFWCHKCGG
                     ISSMRTCPHNSEDRVLLSGTEVRKILSENKELPETFSRPEVAKVLQVYYASIKDEDKI
                     EIKLNDHFTK"
     misc_feature    98096..99271
                     /gene="sat"
                     /locus_tag="COSY_0089"
                     /note="sulfate adenylyltransferase; Reviewed; Region: sat;
                     PRK04149"
                     /db_xref="CDD:235227"
     misc_feature    98198..99229
                     /gene="sat"
                     /locus_tag="COSY_0089"
                     /note="ATP-sulfurylase; Region: ATPS; cd00517"
                     /db_xref="CDD:173895"
     misc_feature    order(98672..98686,98702..98704,98711..98713,98879..98881,
                     98954..98962,98966..98971,99062..99070)
                     /gene="sat"
                     /locus_tag="COSY_0089"
                     /note="active site"
                     /db_xref="CDD:173895"
     misc_feature    98693..98704
                     /gene="sat"
                     /locus_tag="COSY_0089"
                     /note="HXXH motif; other site"
                     /db_xref="CDD:173895"
     misc_feature    98765..98797
                     /gene="sat"
                     /locus_tag="COSY_0089"
                     /note="flexible loop; other site"
                     /db_xref="CDD:173895"
     gene            99516..100385
                     /gene="aprM"
                     /locus_tag="COSY_0090"
                     /db_xref="GeneID:5171802"
     CDS             99516..100385
                     /gene="aprM"
                     /locus_tag="COSY_0090"
                     /note="Similar to hypothetical protein Tbd_2284 (284 aa)
                     in Thiobacillus denitrificans ATCC 25259."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylylsulfate reductase membrane anchor"
                     /protein_id="YP_001218950.1"
                     /db_xref="GI:148244256"
                     /db_xref="GeneID:5171802"
                     /translation="MIDINSTPIASLLAEGISYTNMQMYVVIMIALVIIMTVLDLLHK
                     KSSIYFFSASAKAEKDLFAGNAPCSLGKEEDRLKILSVADKVNILASTVVVDVSTAGE
                     FSNGLRRLVHILTMWGFIFFNVATIIIIFGAQETQILAQVWNIGAIMLFIGTFWYWFG
                     FKVDSQVEGYSWTRVVIRRDMFSLSLMATSVSALGWNIYGGGTGIWFILVLLATISLF
                     GGVYWSKFSHMFFKPIAAYNKRIIKANGTNENLPHETRNDVWQQNRHSMELLKDAPMD
                     MGLGIKREAPKHY"
     gene            100417..100896
                     /gene="aprB"
                     /locus_tag="COSY_0091"
                     /db_xref="GeneID:5172128"
     CDS             100417..100896
                     /gene="aprB"
                     /locus_tag="COSY_0091"
                     /EC_number="1.8.99.2"
                     /note="Similar to adenylylsulfate reductase beta subunit
                     Tbd_2283 (160 aa) in Thiobacillus denitrificans ATCC
                     25259."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylylsulfate reductase beta subunit"
                     /protein_id="YP_001218951.1"
                     /db_xref="GI:148244257"
                     /db_xref="GeneID:5172128"
                     /translation="MPTFVYMTRCDGCGHCVDICPSDIMHIDDKYRRAYNIEPNMCWE
                     CYSCVKACPHQAIDVRGYADFAPLGHSVRVIRDEEKGTIAWRVKFRDGRVKNFLSPIT
                     TQPWGTKIPDLRNEPEPSNDMRNSQLLAFEPKYIRMDDGDIHTLESNGLKFKEGVYY"
     misc_feature    100417..100812
                     /gene="aprB"
                     /locus_tag="COSY_0091"
                     /note="adenosine phosphosulphate reductase, beta subunit;
                     Region: aprB; TIGR02060"
                     /db_xref="CDD:131115"
     misc_feature    <100417..100596
                     /gene="aprB"
                     /locus_tag="COSY_0091"
                     /note="RPB11 and RPB3 subunits of RNA polymerase; Region:
                     RNAP_RPB11_RPB3; cl11409"
                     /db_xref="CDD:245605"
     misc_feature    100591..100857
                     /gene="aprB"
                     /locus_tag="COSY_0091"
                     /note="Adenosine-5&apos;-phosphosulfate reductase beta
                     subunit; Region: APS-reductase_C; pfam12139"
                     /db_xref="CDD:204833"
     gene            100896..102779
                     /gene="aprA"
                     /locus_tag="COSY_0092"
                     /db_xref="GeneID:5172122"
     CDS             100896..102779
                     /gene="aprA"
                     /locus_tag="COSY_0092"
                     /EC_number="1.8.99.2"
                     /note="catalyzes the reduction of adenosine
                     5'-phosphosulfate to AMP and sulfite"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylylsulfate reductase subunit alpha"
                     /protein_id="YP_001218952.1"
                     /db_xref="GI:148244258"
                     /db_xref="GeneID:5172122"
                     /translation="MGIKTIVEDNIDILVVGAGLGGTGAAYEARYWGRNKKIIIAEKA
                     NINRSGAVAQGLYAINCYMGTRFGENNPEDHVRYARMDLMGMVREDLLFDMARHVDSA
                     VHKFEEWGLPLMKDPKREDIGAYMREGRWQIMIHGESYKPIVAEAATKQADKVYNRIM
                     VTHLLMDDEKKNRVAGAVGFNVRTGNYHVFKSKTTIVGAGGASNIFKPRSVGEGMGRV
                     WYAPWSSGSAYGLLIEAGAKMTQMENRIVLARFKDGYGPVGAYFLHLKTYTQNGYGDE
                     YESKWFPALSKMVGKEYLDTEGQHLSHKPIPTCLRNHAFISEVNAGRGPIHMVTMEAF
                     KDPHLEEVGWENFLGMTVGQAVLWAATDVDPKYENPELTTSEPYVMGSHATGCGAWCS
                     GPEDISPDEYFWGYNRMTTVDGLFGAGDTVGGTPHAFSSGSFTEGRLAAKAACKYIDD
                     GKAEGIVVSNKQIAERKEQIYKPLENYTIGRNEIVAGTVSPSYILPMSGLQRLQKIMD
                     EYCGGVTVSYITNDKLLNIGLKKLAILEEDLEHIGAEDLHQLMRGWELRHRHRTSECV
                     TQHTLFRKETRWPGYYYRGDAMKLDDKNWHVLTVSHRNRITGEYTLEKAPCYHLVGEG
                     DEK"
     misc_feature    100896..102764
                     /gene="aprA"
                     /locus_tag="COSY_0092"
                     /note="adenylylsulfate reductase subunit alpha; Validated;
                     Region: PRK06854"
                     /db_xref="CDD:235879"
     misc_feature    102396..102743
                     /gene="aprA"
                     /locus_tag="COSY_0092"
                     /note="Fumarate reductase flavoprotein C-term; Region:
                     Succ_DH_flav_C; pfam02910"
                     /db_xref="CDD:217281"
     gene            102845..103240
                     /locus_tag="COSY_0093"
                     /db_xref="GeneID:5172116"
     CDS             102845..103240
                     /locus_tag="COSY_0093"
                     /note="Similar to hypothetical protein Tbd_2281 (129 aa)
                     in Thiobacillus denitrificans ATCC 25259."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218953.1"
                     /db_xref="GI:148244259"
                     /db_xref="GeneID:5172116"
                     /translation="MCILRKNVFIGVIESMNIIDKTDEEILAIANPMWNNLVKYSNNG
                     NYGAFSRHFSEDFLRGANEIEMGKQFARSELTKGLEKGAGCLGMIRRGQYVTVLYKQT
                     HSKKEGEYLGRLVLGYEDDVVKIFGTTIF"
     gene            103246..103752
                     /locus_tag="COSY_0094"
                     /db_xref="GeneID:5172349"
     CDS             103246..103752
                     /locus_tag="COSY_0094"
                     /EC_number="5.2.1.8"
                     /note="Similar to putative peptidyl-prolyl cis-trans
                     isomerase Tbd_2280 (169 aa) in Thiobacillus denitrificans
                     ATCC 25259. FKBP-type peptidyl-prolyl cis-trans isomerase
                     (Rotamase) protein."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="YP_001218954.1"
                     /db_xref="GI:148244260"
                     /db_xref="GeneID:5172349"
                     /translation="MDNIIKEFKYVELIYKVIDKKTGNIFLSIEYPVGYVHGINDTLG
                     KEVINELEGRRQGDVIEVEIDVDKLYGIRDESLVFIDKIENIPHKYQKVGTKIVMENS
                     KGESKDFLVTKVDDKTVTIDGNNPLCGREVRFILDIHLVRDATDGEMEVGGMTDEQPD
                     IEQLLTVH"
     misc_feature    103258..103701
                     /locus_tag="COSY_0094"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerases 2
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: SlpA; COG1047"
                     /db_xref="CDD:223976"
     gene            103755..104108
                     /locus_tag="COSY_0095"
                     /db_xref="GeneID:5172389"
     CDS             103755..104108
                     /locus_tag="COSY_0095"
                     /note="Similar to hypothetical protein Tbd_1503 (121 aa)
                     in Thiobacillus denitrificans ATCC 25259."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218955.1"
                     /db_xref="GI:148244261"
                     /db_xref="GeneID:5172389"
                     /translation="MSIDFLGSEIKTIQNAVNQRWKKENINVNLADIEITKEGELTLV
                     PAAVWEDKNSTFIILKIGIFSYKSFFYYLTDKRFDTGVSEYNDLYECANTLLKAQADF
                     ILSEHTKDLNLHSFK"
     gene            complement(104183..106183)
                     /gene="hppA"
                     /locus_tag="COSY_0096"
                     /db_xref="GeneID:5172375"
     CDS             complement(104183..106183)
                     /gene="hppA"
                     /locus_tag="COSY_0096"
                     /EC_number="3.6.1.1"
                     /note="pyrophosphate-energized proton pump;
                     pyrophosphate-energized inorganic pyrophosphatase;
                     H+-PPase; can cleave pyrophosphate to two phosphates; can
                     generate a proton motive force and drive pyrophosphate
                     synthesis when PMF is sufficient"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound proton-translocating
                     pyrophosphatase"
                     /protein_id="YP_001218956.1"
                     /db_xref="GI:148244262"
                     /db_xref="GeneID:5172375"
                     /translation="MDIILILAISASTVAVLYGLLTITWINKQPLGNDKMKEISNAIA
                     QGASAYLNRQYSTISIAGVILLIIITYFLGYTVGLGFLVGAVLSGITGYIGMNVSVKS
                     NARTAQAAHNGINAAFQVAFKGGAVTGMLVVGLALLGVSGYYAGMIEYGIAQKDALHA
                     LIGLAFGGSLISIFARLGGGIFTKGADVGADIVGKVEAGIPEDDPRNPAVIADNVGDN
                     VGDCAGMAADLFETYAVTIIATMMLAGVLGLGDNAILYPLALGAISIIASIIGTFFVK
                     VSDNSGSIMGALYKGLTVSAVLAAITFYFITNNMNMGMNLFYASLIGLALTAVMVVVT
                     EYYTSTQYSPVQHVAEASLTGDGTNVIAGIGLSMKSTAFPILAVCTSIWGAYELGGLY
                     AIAISATAMLSMTGVIVALDAYGPITDNAGGIAEMAKLPEKIRNITDPLDAVGNTTKA
                     VTKGYAIGSAGLATLVLFADFTNEISIKFGSNIPFDLSDHKVIIGLFLGGLVPYLFGS
                     MAMEAVGRAAGGIVNEVRRQFKEIPGIMDYTQKPDYSKAVDMLTKSAIKEMILPSILP
                     IAFPVVVGLLLGAEALGGLLIGSITTGIFVAISMTTGGGAWDNAKKYIEDGHFGGKGS
                     DAHKAAITGDTVGDPYKDTAGPAINPLIKIINIVAIMIIPLL"
     misc_feature    complement(104231..106168)
                     /gene="hppA"
                     /locus_tag="COSY_0096"
                     /note="H(+) -translocating inorganic pyrophosphatase;
                     Region: PLN02255; cl11452"
                     /db_xref="CDD:245626"
     misc_feature    complement(104186..106108)
                     /gene="hppA"
                     /locus_tag="COSY_0096"
                     /note="membrane-bound proton-translocating
                     pyrophosphatase; Validated; Region: hppA; PRK00733"
                     /db_xref="CDD:234827"
     gene            complement(106680..107339)
                     /gene="adk"
                     /locus_tag="COSY_0097"
                     /db_xref="GeneID:5172371"
     CDS             complement(106680..107339)
                     /gene="adk"
                     /locus_tag="COSY_0097"
                     /EC_number="2.7.4.3"
                     /note="essential enzyme that recycles AMP in active cells;
                     converts ATP and AMP to two molecules of ADP"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="YP_001218957.1"
                     /db_xref="GI:148244263"
                     /db_xref="GeneID:5172371"
                     /translation="MNIILLGPPGAGKGTQATNICNKYSIPQISTGDMLRVAVKVGTP
                     LGIEAKKIMDSGGLVSDNIIINLVKERIQHSDCKNGFLFDGFPRTITQAEALRKDSVK
                     INFVIEIQVPDQEIIARMSGRRTHLKSGRTYHITYNQPKVEGIDDITGEKLVQRSDDS
                     ENTVRSRLDIYHNQTQPLVNYYQSWMDKDSNAPKYAAAIGIGTLDEVKDRIYNSLISY
                     D"
     misc_feature    complement(106695..107339)
                     /gene="adk"
                     /locus_tag="COSY_0097"
                     /note="adenylate kinase; Reviewed; Region: adk; PRK00279"
                     /db_xref="CDD:234711"
     misc_feature    complement(106719..107336)
                     /gene="adk"
                     /locus_tag="COSY_0097"
                     /note="Adenylate kinase (ADK) catalyzes the reversible
                     phosphoryl transfer from adenosine triphosphates (ATP) to
                     adenosine monophosphates (AMP) and to yield adenosine
                     diphosphates (ADP). This enzyme is required for the
                     biosynthesis of ADP and is essential for...; Region: ADK;
                     cd01428"
                     /db_xref="CDD:238713"
     misc_feature    complement(order(107064..107066,107076..107081,
                     107085..107090,107163..107165,107232..107234,
                     107247..107249))
                     /gene="adk"
                     /locus_tag="COSY_0097"
                     /note="AMP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238713"
     misc_feature    complement(order(106827..106829,106839..106841,
                     106971..106973,107076..107078,107088..107090,
                     107232..107234))
                     /gene="adk"
                     /locus_tag="COSY_0097"
                     /note="ATP-AMP (Ap5A)-binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238713"
     gene            complement(107449..108693)
                     /gene="pfkA"
                     /locus_tag="COSY_0098"
                     /db_xref="GeneID:5171916"
     CDS             complement(107449..108693)
                     /gene="pfkA"
                     /locus_tag="COSY_0098"
                     /EC_number="2.7.1.11"
                     /note="catalyzes the formation of D-fructose
                     1,6-bisphosphate from D-fructose 6-phosphate in
                     glycolysis"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="YP_001218958.1"
                     /db_xref="GI:148244264"
                     /db_xref="GeneID:5171916"
                     /translation="MKNAFYAQSGGVTAVINASACGVIETARKHSNTIGTVYAGKNGI
                     IGALTENLIDTSKESSADIKALKHTPSGGFGSCRYKMKSLETNKAEYERLIEVFKAHN
                     IGYFFYNGGGDSADTCLKVSQLSESMGYPIQAIHIPKTVDNDLPITDNSPGFGSVAKY
                     IAVSTMEASFDVASMAATSTKIFVLEVMGRHAGWIASAGGLVDDSIPVVILFPEVGFD
                     EKKFLAKVDKNVKEFGYCTIVVSEGAKWPDGRFLSEQNTHDDFGHAQLGGVAPIIAKL
                     IKNALGYKYHWAVADYLQRAARHLASKSDVKQAYALGQAAINMALEGKNSVMPTIIRT
                     SNNPYTWKIGSGKLKDIANIEKMMLMNYISNDGFGITEACREYLQPLIEGEDYPPYKN
                     GLPDYVVMKKLMVDKKLPPFGV"
     misc_feature    complement(107458..108693)
                     /gene="pfkA"
                     /locus_tag="COSY_0098"
                     /note="6-phosphofructokinase; Provisional; Region:
                     PRK14072"
                     /db_xref="CDD:237600"
     misc_feature    complement(107710..108669)
                     /gene="pfkA"
                     /locus_tag="COSY_0098"
                     /note="6-phosphofructokinase; Region: PFKA_ATP; TIGR02482"
                     /db_xref="CDD:213713"
     misc_feature    complement(order(107809..107811,107818..107820,
                     107968..107970,108124..108132,108262..108264,
                     108268..108270,108274..108276,108343..108348,
                     108352..108360,108460..108462,108571..108573,
                     108661..108663))
                     /gene="pfkA"
                     /locus_tag="COSY_0098"
                     /note="active site"
                     /db_xref="CDD:238216"
     misc_feature    complement(order(108343..108348,108352..108360,
                     108460..108462,108571..108573,108661..108663))
                     /gene="pfkA"
                     /locus_tag="COSY_0098"
                     /note="ADP/pyrophosphate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238216"
     misc_feature    complement(order(107683..107685,107740..107742,
                     107761..107763,107773..107778,108001..108003,
                     108076..108078,108088..108093,108175..108177,
                     108184..108186,108196..108198,108244..108246,
                     108499..108501,108508..108510,108523..108525,
                     108619..108621,108631..108633))
                     /gene="pfkA"
                     /locus_tag="COSY_0098"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238216"
     misc_feature    complement(order(107995..108003,108007..108009,
                     108070..108072,108076..108078,108175..108177,
                     108508..108513,108520..108525,108619..108621,
                     108631..108633))
                     /gene="pfkA"
                     /locus_tag="COSY_0098"
                     /note="allosteric effector site; other site"
                     /db_xref="CDD:238216"
     misc_feature    complement(order(107809..107811,107818..107820,
                     107836..107838,107968..107970,108124..108132,
                     108151..108153,108262..108264,108268..108270,
                     108274..108276))
                     /gene="pfkA"
                     /locus_tag="COSY_0098"
                     /note="fructose-1,6-bisphosphate binding site; other site"
                     /db_xref="CDD:238216"
     gene            complement(108746..109228)
                     /locus_tag="COSY_0099"
                     /db_xref="GeneID:5171847"
     CDS             complement(108746..109228)
                     /locus_tag="COSY_0099"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218959.1"
                     /db_xref="GI:148244265"
                     /db_xref="GeneID:5171847"
                     /translation="MMNTSIGILSDTHGFIHPNIVKLMNQCDIIIHAGDIIDEKTLQA
                     LIPKQKLIAIQGNNDTHITHLNLIEKLSFSSGNIIIEHGHKHGHHQPSHNSLRAAYPN
                     SKIIIYGHTHKQVIDKIKTPWIINPGAAGKIRNYGGSKCFILKINQFQKWKITPYVFN
                     "
     misc_feature    complement(108767..109213)
                     /locus_tag="COSY_0099"
                     /note="Escherichia coli YfcE and related proteins,
                     metallophosphatase domain; Region: MPP_YfcE; cd00841"
                     /db_xref="CDD:163617"
     misc_feature    complement(order(108893..108895,108899..108901,
                     108983..108985,109055..109060,109124..109126,
                     109190..109192,109196..109198))
                     /locus_tag="COSY_0099"
                     /note="active site"
                     /db_xref="CDD:163617"
     misc_feature    complement(order(108893..108895,108899..108901,
                     108983..108985,109058..109060,109124..109126,
                     109190..109192,109196..109198))
                     /locus_tag="COSY_0099"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163617"
     misc_feature    complement(order(108977..108979,108998..109006,
                     109007..109027,109052..109066,109073..109075,
                     109142..109147))
                     /locus_tag="COSY_0099"
                     /note="homotetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:163617"
     gene            complement(109916..111304)
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /db_xref="GeneID:5172369"
     CDS             complement(109916..111304)
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /EC_number="6.1.1.16"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteinyl-tRNA synthetase"
                     /protein_id="YP_001218960.1"
                     /db_xref="GI:148244266"
                     /db_xref="GeneID:5172369"
                     /translation="MLKIYNTLSKQKEIFHPINNNKVGIYVCGMTVYDYCHMGHARVL
                     VMFDVITRHLRRHFSNVEYVRNITDIDDKIIKRAVENKEDIYTLTNRFINAMHEDEHA
                     LGILPPDVEPRATNTMEQIFCMIKSLIEKGFAYQAHNGDVYYSVRHFKNYGKFSRKNL
                     NKLEIGARIKVESAKKDPLDFVLWKMSKPNEPSWSSPWGKGRPGWHIECSAMSTHHLG
                     NHFDIHGGGMDLTFPHHENEIAQSEGANNCTFVNIWMHVGFVNINNKKMSKSLNNFFT
                     IRNVLKNYNGEILRYFIMSSHYHSPLNFSDENLNKAKSSLSRLYTTIRGLNTSNVRTE
                     EISIHFDYSVRFNEALDDDFNTPIALSVLFELAKIVNIQRENNTDQAKTLAQLLKKLG
                     GYIGILQMNADKFLKQGISLSDEQINIKITNRNKARINKDFTLSDYIRDELAKFDIIL
                     EDNINGTTWRKK"
     misc_feature    complement(109919..111304)
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /note="cysteinyl-tRNA synthetase; Validated; Region: cysS;
                     PRK00260"
                     /db_xref="CDD:234705"
     misc_feature    complement(<110963..111298)
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /note="catalytic core domain of cysteinyl tRNA synthetase;
                     Region: CysRS_core; cd00672"
                     /db_xref="CDD:173899"
     misc_feature    complement(order(111101..111103,111107..111109,
                     111173..111178,111185..111190,111194..111196,
                     111212..111223))
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /note="active site"
                     /db_xref="CDD:173899"
     misc_feature    complement(111185..111196)
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173899"
     misc_feature    complement(110390..>110692)
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /note="catalytic core domain of cysteinyl tRNA synthetase;
                     Region: CysRS_core; cd00672"
                     /db_xref="CDD:173899"
     misc_feature    complement(110495..110509)
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173899"
     misc_feature    complement(109922..110389)
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /note="Anticodon-binding domain of cysteinyl tRNA
                     synthetases; Region: Anticodon_Ia_Cys; cd07963"
                     /db_xref="CDD:153417"
     misc_feature    complement(order(109925..109927,109949..109960,
                     109985..109987,109994..109996,110006..110008,
                     110021..110023,110033..110035,110192..110194,
                     110201..110203,110210..110215,110222..110224,
                     110231..110236,110240..110242,110333..110335,
                     110342..110344,110351..110353,110360..110362,
                     110372..110374,110381..110383))
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /note="tRNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:153417"
     misc_feature    complement(order(109949..109957,109985..109987,
                     109994..109996,110006..110008,110021..110023,
                     110033..110035))
                     /gene="cysS"
                     /locus_tag="COSY_0100"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:153417"
     gene            111445..112044
                     /gene="ahpC"
                     /locus_tag="COSY_0101"
                     /db_xref="GeneID:5172173"
     CDS             111445..112044
                     /gene="ahpC"
                     /locus_tag="COSY_0101"
                     /note="AhpC/TSA family"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="YP_001218961.1"
                     /db_xref="GI:148244267"
                     /db_xref="GeneID:5172173"
                     /translation="MNVLVTQQAPDFKAAAVLADGTIVNNFQLSDFKGKKIVLFFYPL
                     DFTFVCPSEILAHHHRMMQFNEKGVKVVGVSVDSQFTHNAWRKIDPMDGGLGVIDFPL
                     VADTNHSIMKSYGIVHPTGVALRASFLIDESFDIRHQVVNDLPLGRNVDEILRMVDAL
                     DFHSKHGEVCPAGWNDGDEGMKDTPAGVANYLSQYADKL"
     misc_feature    111451..112041
                     /gene="ahpC"
                     /locus_tag="COSY_0101"
                     /note="peroxidase; Provisional; Region: PRK15000"
                     /db_xref="CDD:184962"
     misc_feature    111457..111975
                     /gene="ahpC"
                     /locus_tag="COSY_0101"
                     /note="Peroxiredoxin (PRX) family, Typical 2-Cys PRX
                     subfamily; PRXs are thiol-specific antioxidant (TSA)
                     proteins, which confer a protective role in cells through
                     its peroxidase activity by reducing hydrogen peroxide,
                     peroxynitrite, and organic hydroperoxides; Region:
                     PRX_Typ2cys; cd03015"
                     /db_xref="CDD:239313"
     misc_feature    order(111457..111459,111586..111591,111598..111600,
                     111787..111789,111814..111816,111853..111861,
                     111865..111873,111883..111888,111907..111909,
                     111952..111963)
                     /gene="ahpC"
                     /locus_tag="COSY_0101"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239313"
     misc_feature    order(111580..111582,111682..111687,111760..111762,
                     111766..111768)
                     /gene="ahpC"
                     /locus_tag="COSY_0101"
                     /note="decamer (pentamer of dimers) interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239313"
     misc_feature    order(111583..111585,111592..111594,111817..111819)
                     /gene="ahpC"
                     /locus_tag="COSY_0101"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:239313"
     misc_feature    order(111592..111594,111952..111954)
                     /gene="ahpC"
                     /locus_tag="COSY_0101"
                     /note="peroxidatic and resolving cysteines [active]"
                     /db_xref="CDD:239313"
     gene            112092..112262
                     /gene="rubA"
                     /locus_tag="COSY_0102"
                     /db_xref="GeneID:5171978"
     CDS             112092..112262
                     /gene="rubA"
                     /locus_tag="COSY_0102"
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin"
                     /protein_id="YP_001218962.1"
                     /db_xref="GI:148244268"
                     /db_xref="GeneID:5171978"
                     /translation="MVMKKYRCIVCGWVYDEYLSTSKEGAELGQKWENIPEDWVCPDC
                     GASKSEFEIVKI"
     misc_feature    112098..112259
                     /gene="rubA"
                     /locus_tag="COSY_0102"
                     /note="Rubredoxin [Energy production and conversion];
                     Region: COG1773"
                     /db_xref="CDD:224687"
     misc_feature    112104..112247
                     /gene="rubA"
                     /locus_tag="COSY_0102"
                     /note="Rubredoxin; nonheme iron binding domains containing
                     a [Fe(SCys)4] center. Rubredoxins are small nonheme iron
                     proteins. The iron atom is coordinated by four cysteine
                     residues (Fe(S-Cys)4), but iron can also be replaced by
                     cobalt, nickel or zinc. They are...; Region: rubredoxin;
                     cd00730"
                     /db_xref="CDD:238372"
     misc_feature    order(112113..112115,112122..112124,112212..112214,
                     112221..112223)
                     /gene="rubA"
                     /locus_tag="COSY_0102"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238372"
     gene            112298..113368
                     /gene="leuB"
                     /locus_tag="COSY_0103"
                     /db_xref="GeneID:5172449"
     CDS             112298..113368
                     /gene="leuB"
                     /locus_tag="COSY_0103"
                     /EC_number="1.1.1.85"
                     /note="catalyzes the oxidation of 3-isopropylmalate to
                     3-carboxy-4-methyl-2-oxopentanoate in leucine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="YP_001218963.1"
                     /db_xref="GI:148244269"
                     /db_xref="GeneID:5172449"
                     /translation="MSKVLILPGDGIGQEVVIQALKVIDFLNANFNLGMTLEHGLIGG
                     SAYDVTGSPLPQDTLDVARKCDSILLGAVGGYKWESLLRDLRPERGLLRLRAEMDLFS
                     NLRPAILYSQLISASTLKKEVVLGLDLMIIRELVSGIYFGKPRGIEIRNGQRYGFNTA
                     TYFESEIRRIGHSAFKIAQLRNKRVCSVDKANVLEVCELWRKVMIDLAKDYPDVELSH
                     MYVDNVAMQLVRAPKQFDVIVTSNLFGDVLSDCAAMLTGSIGMLPSASLNQYGFGMYE
                     PIHGSAPDIEGKDIANPLAAILSVAMMLRYSLNQAHLAFKIEAAVNAVLDKGYRTLDI
                     LTEGGMVVGTNEMGNLVVEALV"
     misc_feature    112298..113362
                     /gene="leuB"
                     /locus_tag="COSY_0103"
                     /note="3-isopropylmalate dehydrogenase; Provisional;
                     Region: PRK00772"
                     /db_xref="CDD:234832"
     misc_feature    112304..113362
                     /gene="leuB"
                     /locus_tag="COSY_0103"
                     /note="tartrate dehydrogenase; Region: TTC; TIGR02089"
                     /db_xref="CDD:233718"
     gene            complement(114386..115339)
                     /locus_tag="COSY_0104"
                     /db_xref="GeneID:5172564"
     CDS             complement(114386..115339)
                     /locus_tag="COSY_0104"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218964.1"
                     /db_xref="GI:148244270"
                     /db_xref="GeneID:5172564"
                     /translation="MKTIYLLFTLTLSTLSNAWKIEGIGEFSPEKISNNLFVIHGPFG
                     KPNIQNQGFINNPGIIIGKEGVIIIDPGSSYDIGKKVIKEVEKITKKPIISVFNTHIH
                     GDHWLGNHAIIEKYPNTKIYAHPQMIIEAKNGKGNKWINIMTTLTNGLTKDTIATYPT
                     NPIKHLQVIKLDSEQFKIHNPTIKSHTNTDIMIEHINSKTLFLGDNSFVNRMGPFDNS
                     SSIHDNIKVLQYATNLGLNYYVPGHGSSGNVNHTVKPFLDYLLIIQSEAKKGYEKDFT
                     DYEIKPIAIKKLNSYKNWHGFYGQLGNHISKVLLEVEALEL"
     misc_feature    complement(114611..>115054)
                     /locus_tag="COSY_0104"
                     /note="Metallo-beta-lactamase superfamily; Region:
                     Lactamase_B; smart00849"
                     /db_xref="CDD:214854"
     gene            115792..116337
                     /gene="nudE"
                     /locus_tag="COSY_0105"
                     /db_xref="GeneID:5172400"
     CDS             115792..116337
                     /gene="nudE"
                     /locus_tag="COSY_0105"
                     /EC_number="3.6.1.-"
                     /note="ADP-sugar pyrophosphatase; catalyzes the formation
                     of D-ribose 5-phosphate from ADP-ribose; can also act on
                     ADP-mannose and ADP-glucose"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase NudE"
                     /protein_id="YP_001218965.1"
                     /db_xref="GI:148244271"
                     /db_xref="GeneID:5172400"
                     /translation="MRKKPTVLNIKTIATTNFFNIEEMDIKFSNGEKRIYERLKPFEN
                     GAVLIVPMLDDETVLMIYEYSGGTDKYELVLTKGKIDDNEILVEAANRELIEEIGFGA
                     NKLTFIKKMTIAPSYQSSITYIVLAQDLYKAKAQGDEPELLEVVTFRMADLENLVYNE
                     HLTEARSIAALYMARDMINNQ"
     misc_feature    115792..116334
                     /gene="nudE"
                     /locus_tag="COSY_0105"
                     /note="adenosine nucleotide hydrolase NudE; Provisional;
                     Region: nudE; PRK11762"
                     /db_xref="CDD:183303"
     misc_feature    115924..116316
                     /gene="nudE"
                     /locus_tag="COSY_0105"
                     /note="ADP-ribose pyrophosphatase (ADPRase) catalyzes the
                     hydrolysis of ADP-ribose and a variety of additional
                     ADP-sugar conjugates to AMP and ribose-5-phosphate. Like
                     other members of the Nudix hydrolase superfamily, it
                     requires a divalent cation, such as Mg2+; Region:
                     ADPRase_NUDT5; cd03424"
                     /db_xref="CDD:239516"
     misc_feature    order(115924..115926,115975..115977,115981..115983,
                     115987..115989,116002..116004,116119..116130,
                     116134..116136,116140..116154,116212..116217,
                     116221..116223,116260..116265,116284..116286,
                     116296..116298,116305..116307)
                     /gene="nudE"
                     /locus_tag="COSY_0105"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239516"
     misc_feature    order(115927..115929,115984..115986,116026..116028,
                     116068..116070,116080..116082,116149..116151)
                     /gene="nudE"
                     /locus_tag="COSY_0105"
                     /note="ADP-ribose binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239516"
     misc_feature    order(115984..115986,116020..116028,116068..116070,
                     116080..116082,116149..116151,116212..116214)
                     /gene="nudE"
                     /locus_tag="COSY_0105"
                     /note="active site"
                     /db_xref="CDD:239516"
     misc_feature    order(116023..116034,116038..116091)
                     /gene="nudE"
                     /locus_tag="COSY_0105"
                     /note="nudix motif; other site"
                     /db_xref="CDD:239516"
     misc_feature    order(116068..116070,116080..116082,116212..116214)
                     /gene="nudE"
                     /locus_tag="COSY_0105"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:239516"
     gene            117062..118303
                     /gene="lysA"
                     /locus_tag="COSY_0106"
                     /db_xref="GeneID:5172620"
     CDS             117062..118303
                     /gene="lysA"
                     /locus_tag="COSY_0106"
                     /EC_number="4.1.1.20"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="YP_001218966.1"
                     /db_xref="GI:148244272"
                     /db_xref="GeneID:5172620"
                     /translation="MGFSYQNHILHAESVAIADLMKTYGSPLYVYSRTDIEYNWHLFS
                     HAFGIHPHLVCYAVKANSNLAVLSVLAKIGSGFDVVSNGELERILLAGADASRCVFSG
                     VAKTNIEIKRALEVGIFCFNVESMAEMIRIEQVAKEMSMQAPISLRVNPDVDAKTHPY
                     ISTGLKENKFGVDIDDAIPIYKMAYNSPYLKVKGIDCHIGSQLTKISPFLDALDKVLE
                     LVAKLGKLNIHVTHLDLGGGVGIKYDNEQTIDINAYISSILDKVGSLKIILEPGRAIV
                     GNAGIFVTKVEFLKQNSDKSFAIIDGAMNDLLRPSFYQAYHQVLPIDENAEGIDAHWD
                     LVGPICETGDFLAKNRRLSLSEGDYLALMSAGAYGSTMSSNYNSRPRVAEVMVLGSQY
                     TLVRERETIQDLFNKEYMIND"
     misc_feature    117071..118285
                     /gene="lysA"
                     /locus_tag="COSY_0106"
                     /note="diaminopimelate decarboxylase; Region: lysA;
                     TIGR01048"
                     /db_xref="CDD:233248"
     misc_feature    117131..118222
                     /gene="lysA"
                     /locus_tag="COSY_0106"
                     /note="Type III Pyridoxal 5-phosphate (PLP)-Dependent
                     Enzyme Diaminopimelate Decarboxylase; Region:
                     PLPDE_III_DapDC; cd06828"
                     /db_xref="CDD:143501"
     misc_feature    order(117230..117232,117236..117238,117293..117295,
                     117362..117364,117503..117505,117647..117649,
                     117653..117655,117662..117664,117770..117775,
                     117869..117880,117986..117988,117998..118000,
                     118079..118081,118163..118165,118175..118177,
                     118187..118189)
                     /gene="lysA"
                     /locus_tag="COSY_0106"
                     /note="active site"
                     /db_xref="CDD:143501"
     misc_feature    order(117230..117232,117236..117238,117293..117295,
                     117362..117364,117503..117505,117647..117649,
                     117653..117655,117662..117664,117770..117775,
                     117869..117880,118079..118081,118163..118165)
                     /gene="lysA"
                     /locus_tag="COSY_0106"
                     /note="pyridoxal 5'-phosphate (PLP) binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:143501"
     misc_feature    order(117236..117238,117653..117655,117662..117664,
                     117878..117880,117986..117988,117998..118000,
                     118079..118084,118163..118165,118175..118177,
                     118187..118189)
                     /gene="lysA"
                     /locus_tag="COSY_0106"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:143501"
     misc_feature    order(117236..117238,118079..118081)
                     /gene="lysA"
                     /locus_tag="COSY_0106"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143501"
     misc_feature    order(117251..117256,117299..117304,117308..117313,
                     117368..117376,117386..117388,117431..117433,
                     117440..117442,117563..117574,117923..117925,
                     117929..117931,117950..117952,117956..117958,
                     118070..118087,118091..118093,118172..118180,
                     118184..118195,118202..118204)
                     /gene="lysA"
                     /locus_tag="COSY_0106"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143501"
     gene            118296..118598
                     /locus_tag="COSY_0107"
                     /db_xref="GeneID:5172249"
     CDS             118296..118598
                     /locus_tag="COSY_0107"
                     /note="Similar to RNA-binding protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218967.1"
                     /db_xref="GI:148244273"
                     /db_xref="GeneID:5172249"
                     /translation="MTKLTNNQKKFLRSKSHSLKPIVMAGQHGLNESVLAELEITMDK
                     HELLKIKIRMDKRAEKQKIIDKIINTYHAHLVQIIGNIVVIYRAFDEDPQIILPRK"
     misc_feature    118305..118556
                     /locus_tag="COSY_0107"
                     /note="CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY;
                     pfam01985"
                     /db_xref="CDD:190184"
     gene            118605..119690
                     /gene="lpxB"
                     /locus_tag="COSY_0108"
                     /db_xref="GeneID:5172398"
     CDS             118605..119690
                     /gene="lpxB"
                     /locus_tag="COSY_0108"
                     /EC_number="2.4.1.182"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="YP_001218968.1"
                     /db_xref="GI:148244274"
                     /db_xref="GeneID:5172398"
                     /translation="MRIAISATEASGDLIGSKLVESLRKQNSNIIIEGLVGDKMFAAG
                     CIQNWDQRQVNVMGFSEILKKLPFLFILRKRIIAYFSSQKPDVFIGIDAPDFNFVIER
                     KLKSKGIKTIHFISPSVWAWRQSRVKKIKQSTDLILCLFPFEVDFYQAYNQRALFIGH
                     PLAQSLHPRRSHIKTKNILLMPGSRQSEIKRLLPEMLLAVEIMSLQDRMLTFNLVLVN
                     DELLDWVTIQVGNIPVEISFDDAHTRMLRADLALVASGTAALELTLIGVPMVVIYKLS
                     RFSYFIASRLVKSKYISLPNIIVNKNLVPELIQNSANGDNIAKHAMIIMSRDNKALIQ
                     EFNAIHQQLDLDASDESARIIYEFINE"
     misc_feature    118605..119684
                     /gene="lpxB"
                     /locus_tag="COSY_0108"
                     /note="lipid-A-disaccharide synthase; Reviewed; Region:
                     lpxB; PRK00025"
                     /db_xref="CDD:234580"
     misc_feature    118605..119561
                     /gene="lpxB"
                     /locus_tag="COSY_0108"
                     /note="ipid-A-disaccharide synthase; Provisional; Region:
                     PRK14089"
                     /db_xref="CDD:237606"
     gene            119641..120504
                     /gene="nadC"
                     /locus_tag="COSY_0109"
                     /db_xref="GeneID:5172279"
     CDS             119641..120504
                     /gene="nadC"
                     /locus_tag="COSY_0109"
                     /EC_number="2.4.2.19"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide pyrophosphorylase
                     (carboxylating)"
                     /protein_id="YP_001218969.1"
                     /db_xref="GI:148244275"
                     /db_xref="GeneID:5172279"
                     /translation="MLVMSQHVLFMSLSTNKYVLNSVVLALEEDLGTGDVSADLLLDK
                     INTAEIISRESGIICGIEYAQSTFLLLNDNLKLDWKVKDGEDINPGQVLCVLKGSSKA
                     IISAERVALNFLQMLSSVATRTHYLVNKINHTNAQLLDTRKTIIGLRFAQKYAVKCGG
                     GVNHRMGLYDCVILKENHIIASGSITLSVKIAIEKYPNLPLIVEVEDLNQLQEVLKLS
                     GITRALCDNFLISDLIQAVVMAKGKLPLEASGNINESTIVEVANTGIDFISIGSITKN
                     IQAIDLSLRFI"
     misc_feature    119704..120498
                     /gene="nadC"
                     /locus_tag="COSY_0109"
                     /note="quinolinate phosphoribosyltransferase; Validated;
                     Region: PRK09016"
                     /db_xref="CDD:181612"
     misc_feature    119713..120495
                     /gene="nadC"
                     /locus_tag="COSY_0109"
                     /note="Quinolinate phosphoribosyl transferase (QAPRTase or
                     QPRTase), also called nicotinate-nucleotide
                     pyrophosphorylase, is involved in the de novo synthesis of
                     NAD in both prokaryotes and eukaryotes. It catalyses the
                     reaction of quinolinic acid (QA) with...; Region: QPRTase;
                     cd01572"
                     /db_xref="CDD:238806"
     misc_feature    order(119749..119754,119959..119964,119974..119976,
                     120064..120066,120070..120072,120082..120087,
                     120142..120147,120157..120159,120163..120165,
                     120169..120174,120181..120183,120214..120216,
                     120463..120465)
                     /gene="nadC"
                     /locus_tag="COSY_0109"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238806"
     misc_feature    order(120061..120069,120130..120135,120316..120318,
                     120385..120390,120445..120447,120451..120456,
                     120463..120465)
                     /gene="nadC"
                     /locus_tag="COSY_0109"
                     /note="active site"
                     /db_xref="CDD:238806"
     gene            complement(120490..121272)
                     /gene="cysQ"
                     /locus_tag="COSY_0110"
                     /db_xref="GeneID:5172002"
     CDS             complement(120490..121272)
                     /gene="cysQ"
                     /locus_tag="COSY_0110"
                     /EC_number="3.1.3.7"
                     /note="PAPS (adenosine 3'-phosphate 5'-phosphosulfate)
                     3'(2'),5'-bisphosphate nucleotidase, converts PAPS to
                     APS."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite synthesis pathway protein CysQ"
                     /protein_id="YP_001218970.1"
                     /db_xref="GI:148244276"
                     /db_xref="GeneID:5172002"
                     /translation="MRYDNIAMFDLLIPKLIRMTTKVGDMIMSLYENELNIKIKSNKT
                     PFTIADKNAHKLIVKTLSKLTPNTPIISEESEIIEFSERSKWCEYWIIDPLDGTRDFL
                     KQTDEFCICIAYIKKHKPIFGMIYAPPRKTHYYTTDANKVFKQQKNIIQPLNVRPNHN
                     PLRVVIGHWSSHNKQLKDHLKKYSTYKLSQLGSALKFCAIAEGKYDYYPKFGPCSEWD
                     TAAGVCILQNAGGSVVNQNEKPLSYNTKNDLTSPIFFASNKP"
     misc_feature    complement(120526..121251)
                     /gene="cysQ"
                     /locus_tag="COSY_0110"
                     /note="Archaeal fructose-1,6-bisphosphatase and related
                     enzymes of inositol monophosphatase family [Carbohydrate
                     transport and metabolism]; Region: SuhB; COG0483"
                     /db_xref="CDD:223559"
     misc_feature    complement(120505..121239)
                     /gene="cysQ"
                     /locus_tag="COSY_0110"
                     /note="CysQ, a
                     3&apos;-Phosphoadenosine-5&apos;-phosphosulfate (PAPS)
                     3&apos;-phosphatase, is a bacterial member of the inositol
                     monophosphatase family. It has been proposed that CysQ
                     helps control intracellular levels of PAPS, which is an
                     intermediate in...; Region: CysQ; cd01638"
                     /db_xref="CDD:238816"
     misc_feature    complement(order(120619..120624,120649..120651,
                     120685..120687,120760..120762,120772..120774,
                     120973..120975,120979..120996,121051..121056,
                     121123..121125))
                     /gene="cysQ"
                     /locus_tag="COSY_0110"
                     /note="active site"
                     /db_xref="CDD:238816"
     gene            complement(121650..121726)
                     /locus_tag="COSY_t05"
                     /db_xref="GeneID:5329745"
     tRNA            complement(121650..121726)
                     /locus_tag="COSY_t05"
                     /product="tRNA-Met"
                     /db_xref="GeneID:5329745"
     gene            complement(121734..123545)
                     /gene="rpoD"
                     /locus_tag="COSY_0112"
                     /db_xref="GeneID:5172171"
     CDS             complement(121734..123545)
                     /gene="rpoD"
                     /locus_tag="COSY_0112"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase sigma-70 factor"
                     /protein_id="YP_001218971.1"
                     /db_xref="GI:148244277"
                     /db_xref="GeneID:5172171"
                     /translation="MKSTTKAHKQALQKLIMVGKEKGYLTYSEINDILPEDLLTQEQV
                     EPIVTILEELDITVSDTVPDADTLVVESGAKAQSTSAEAAIAALAALDSEFGRTTDPV
                     RMYMREMGVVDLLEQEDEIRIAKEIEAGVFEIMQSITLYPVITDFFFKAHTRLEEGKC
                     KMTDVIIGYQGDAEDFANKKVAFDAGEFDNDEEYEEIEEMEYTGPDKNQVYNRFDTVL
                     KYSKTYNKTTEQLGFRHKKTIKTRQQLSKGLSDLRLAPKLVNTMIEVICNRVSQVKEQ
                     EKIIKNICLDAGINRLHFFELFSNNETNFNWLDTVKLDEKIEKNLKDSKDKIYYAQKN
                     LQQFEEEMQLTIVELKKLNKMYRRGDRRAKKAKSQMIEANLRLVISIAKKYANRGLQF
                     LDLIQEGNVGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIET
                     INKLNRVRRQLLQKFGREASSEELATEMELPEYKIIKILKIAKEPLSMETPVGDDEDS
                     NIGDFIEDTNLSSPVEITTKESLRETTGDLLSNLSPREAKVLKMRFGINMNTDHTLEE
                     VGRQFDVTRERIRQIEAKALRKLRHPSRAHKLQSFLE"
     misc_feature    complement(121737..123545)
                     /gene="rpoD"
                     /locus_tag="COSY_0112"
                     /note="RNA polymerase sigma factor RpoD; Validated;
                     Region: PRK05658"
                     /db_xref="CDD:235549"
     misc_feature    complement(123330..123515)
                     /gene="rpoD"
                     /locus_tag="COSY_0112"
                     /note="Sigma-70 factor, region 1.1; Region: Sigma70_r1_1;
                     pfam03979"
                     /db_xref="CDD:217827"
     misc_feature    complement(123144..123251)
                     /gene="rpoD"
                     /locus_tag="COSY_0112"
                     /note="Sigma-70 factor, region 1.2; Region: Sigma70_r1_2;
                     pfam00140"
                     /db_xref="CDD:201030"
     misc_feature    complement(122529..123125)
                     /gene="rpoD"
                     /locus_tag="COSY_0112"
                     /note="Sigma-70, non-essential region; Region:
                     Sigma70_ner; pfam04546"
                     /db_xref="CDD:203043"
     misc_feature    complement(122226..122438)
                     /gene="rpoD"
                     /locus_tag="COSY_0112"
                     /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542"
                     /db_xref="CDD:218138"
     misc_feature    complement(121968..122201)
                     /gene="rpoD"
                     /locus_tag="COSY_0112"
                     /note="Sigma-70 region 3; Region: Sigma70_r3; pfam04539"
                     /db_xref="CDD:146934"
     misc_feature    complement(121776..121952)
                     /gene="rpoD"
                     /locus_tag="COSY_0112"
                     /note="Sigma70, region (SR) 4 refers to the most
                     C-terminal of four conserved domains found in Escherichia
                     coli (Ec) sigma70, the main housekeeping sigma, and
                     related sigma-factors (SFs). A SF is a dissociable subunit
                     of RNA polymerase, it directs bacterial or...; Region:
                     Sigma70_r4; cd06171"
                     /db_xref="CDD:100119"
     misc_feature    complement(order(121788..121790,121794..121799,
                     121803..121811,121815..121820,121824..121826,
                     121854..121859,121887..121889,121917..121919))
                     /gene="rpoD"
                     /locus_tag="COSY_0112"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:100119"
     gene            complement(123645..124598)
                     /gene="prsA"
                     /locus_tag="COSY_0113"
                     /db_xref="GeneID:5172621"
     CDS             complement(123645..124598)
                     /gene="prsA"
                     /locus_tag="COSY_0113"
                     /EC_number="2.7.6.1"
                     /note="phosphoribosyl pyrophosphate synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="YP_001218972.1"
                     /db_xref="GI:148244278"
                     /db_xref="GeneID:5172621"
                     /translation="MSLDKIKIFSGNANPELSREIISSLNVVQGKALVSRFSDGEPQI
                     EILENVRGCDVFIIQPTCGPSPAETLMELLIIVDALKRSSATRITAVVPYFGYSRQDR
                     RSRLTRVPITAKLAAKLIESAGVDRILTVDLHADQIQGFFNIPIDNIYAQPVLIEDIL
                     SKNYKDIVVVSPDVGGVVRARSAAKRLNDAELAIIDKRRPAPNMVKIMNVIGDVKGRS
                     CILIDDMVDTAGTLCQAASILKQRGAKEVVAYATHAVLSGNAINNINNSQLNELITTN
                     TIPLNIDVANCFKIRQLSIAPTMAEVIKRISEEQSISTIFT"
     misc_feature    complement(123651..124583)
                     /gene="prsA"
                     /locus_tag="COSY_0113"
                     /note="ribose-phosphate pyrophosphokinase; Provisional;
                     Region: PRK01259"
                     /db_xref="CDD:234929"
     misc_feature    complement(124227..124583)
                     /gene="prsA"
                     /locus_tag="COSY_0113"
                     /note="N-terminal domain of ribose phosphate
                     pyrophosphokinase; Region: Pribosyltran_N; pfam13793"
                     /db_xref="CDD:222383"
     misc_feature    complement(123825..124142)
                     /gene="prsA"
                     /locus_tag="COSY_0113"
                     /note="Phosphoribosyl transferase (PRT)-type I domain;
                     Region: PRTases_typeI; cd06223"
                     /db_xref="CDD:206754"
     misc_feature    complement(order(123834..123836,123906..123920,
                     123924..123932,124074..124076,124080..124082))
                     /gene="prsA"
                     /locus_tag="COSY_0113"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            complement(124668..124742)
                     /locus_tag="COSY_t06"
                     /db_xref="GeneID:5329764"
     tRNA            complement(124668..124742)
                     /locus_tag="COSY_t06"
                     /product="tRNA-Gln"
                     /db_xref="GeneID:5329764"
     gene            complement(124722..125579)
                     /gene="ipk"
                     /locus_tag="COSY_0115"
                     /db_xref="GeneID:5171959"
     CDS             complement(124722..125579)
                     /gene="ipk"
                     /locus_tag="COSY_0115"
                     /EC_number="2.7.1.148"
                     /note="An essential enzyme in the nonmevalonate pathway of
                     isopentenyl diphosphate and dimethylallyl diphosphate
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2-C-methyl-D-erythritol
                     kinase"
                     /protein_id="YP_001218973.1"
                     /db_xref="GI:148244279"
                     /db_xref="GeneID:5171959"
                     /translation="MPSTWLAPAKINLFLHINKRRKDNYHNLQTIFQLLDYCDKLTCT
                     ITNNGVIKRTSGNKSVKQDQDLIIKAAKALQQYTGTTLGANLSIVKNIPIGGGLGGGS
                     SDAATTLVALNQLWDTKLTQAQLMKLGLNLGADVPVFIFAQSAWAEGIGNILSPIKTP
                     DHYFLVVFINKHISTKEIFSHYALTISEPQGKIANFSELVNTHNDCLQVAIKLEAEIG
                     VALEHLNTCYNRVGQARMSGTGSCVFNEFLTEKDALAAAKKVPKKWMSFVTRAINNSP
                     IYNWAVAKR"
     misc_feature    complement(124764..125579)
                     /gene="ipk"
                     /locus_tag="COSY_0115"
                     /note="4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;
                     Provisional; Region: ipk; PRK00343"
                     /db_xref="CDD:234731"
     misc_feature    complement(125157..125324)
                     /gene="ipk"
                     /locus_tag="COSY_0115"
                     /note="GHMP kinases N terminal domain; Region:
                     GHMP_kinases_N; pfam00288"
                     /db_xref="CDD:215839"
     gene            complement(125572..126117)
                     /gene="orn"
                     /locus_tag="COSY_0116"
                     /db_xref="GeneID:5172690"
     CDS             complement(125572..126117)
                     /gene="orn"
                     /locus_tag="COSY_0116"
                     /note="3'-5' exoribonuclease specific for small
                     oligoribonuclotides"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="YP_001218974.1"
                     /db_xref="GI:148244280"
                     /db_xref="GeneID:5172690"
                     /translation="MINKDTNLIWIDLEMTGLTPEKDVIIEIATIVTDAQLHIIAQGP
                     SLAIHQNDKILTSMNQWNTEHHTNSGLLKRVRKSNVSCKKAEIHTLKFLKKYVNKGAS
                     PMCGNTICQDRRFLYNYMPTLEQFFHYRHIDVSTLKELIMHWKPNEKMVFKKDSAHLA
                     LSDIQDSIDELKHYRNVFINA"
     misc_feature    complement(125581..126096)
                     /gene="orn"
                     /locus_tag="COSY_0116"
                     /note="DEDDh 3&apos;-5&apos; exonuclease domain of
                     oligoribonuclease and similar proteins; Region: Orn;
                     cd06135"
                     /db_xref="CDD:99838"
     misc_feature    complement(order(125629..125631,125644..125646,
                     125782..125784,126076..126078,126082..126084))
                     /gene="orn"
                     /locus_tag="COSY_0116"
                     /note="catalytic site [active]"
                     /db_xref="CDD:99838"
     misc_feature    complement(order(125629..125631,125644..125646,
                     125782..125790,125794..125799,126067..126069,
                     126073..126084))
                     /gene="orn"
                     /locus_tag="COSY_0116"
                     /note="putative active site [active]"
                     /db_xref="CDD:99838"
     misc_feature    complement(order(125629..125631,125644..125646,
                     125785..125790,125794..125799,126067..126069,
                     126073..126084))
                     /gene="orn"
                     /locus_tag="COSY_0116"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:99838"
     misc_feature    complement(order(125581..125586,125590..125592,
                     125683..125688,125701..125703,125710..125712,
                     125719..125721,125725..125730,125767..125769,
                     125776..125778,125785..125790,126013..126015))
                     /gene="orn"
                     /locus_tag="COSY_0116"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:99838"
     gene            complement(126130..127149)
                     /gene="trpD"
                     /locus_tag="COSY_0117"
                     /db_xref="GeneID:5171895"
     CDS             complement(126130..127149)
                     /gene="trpD"
                     /locus_tag="COSY_0117"
                     /EC_number="2.4.2.18"
                     /note="Catalyzes the conversion of
                     N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to
                     anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="YP_001218975.1"
                     /db_xref="GI:148244281"
                     /db_xref="GeneID:5171895"
                     /translation="MNIQQAIKQIVKKQDLSQNEMQKVMNDIMTGKTTDTQTSGFLVG
                     LAIKGESIDEITAVVKIIRSFTKSVTIKNTKHLVDTCGTGGDGLGLFNISTACAFVVA
                     AAGGSVAKHGNRGISSKSGSADVLKAAGVNLNMSVERISKCIEKIGIGFMFAPFHHHS
                     IKYTTNVRKDLAIKTIFNIVGPLTNPAKVPNQIIGVYTQNLVEPIAHVLKKLGSKHII
                     VVHSKDGLDEISIADDTFVAELKNGKIKTYTINPTNFGLPLGNLDDIKVNNADDSLIL
                     IQQALDGKDSVAKNIVALNSGAAIYVCELANSLQEGVSKALKILNSGVAHQKLDDFVR
                     ESTGC"
     misc_feature    complement(126142..127107)
                     /gene="trpD"
                     /locus_tag="COSY_0117"
                     /note="anthranilate phosphoribosyltransferase;
                     Provisional; Region: trpD; PRK00188"
                     /db_xref="CDD:234682"
     misc_feature    complement(126949..127107)
                     /gene="trpD"
                     /locus_tag="COSY_0117"
                     /note="Glycosyl transferase family, helical bundle domain;
                     Region: Glycos_trans_3N; pfam02885"
                     /db_xref="CDD:145834"
     misc_feature    complement(126175..126879)
                     /gene="trpD"
                     /locus_tag="COSY_0117"
                     /note="Glycosyl transferase family, a/b domain; Region:
                     Glycos_transf_3; pfam00591"
                     /db_xref="CDD:216013"
     gene            complement(127154..128371)
                     /gene="pepP"
                     /locus_tag="COSY_0118"
                     /db_xref="GeneID:5172366"
     CDS             complement(127154..128371)
                     /gene="pepP"
                     /locus_tag="COSY_0118"
                     /EC_number="3.4.11.9"
                     /note="aminopeptidase P"
                     /codon_start=1
                     /transl_table=11
                     /product="X-Pro aminopeptidase"
                     /protein_id="YP_001218976.1"
                     /db_xref="GI:148244282"
                     /db_xref="GeneID:5172366"
                     /translation="MIHQKRRLSLLNQLDNNAVVIISSNSEQNRSGDVNYPFRVHSDF
                     YYLTGLQEPKALAIFSKNNYTIFLRPKDKTCEIWGEQRLGIDDASNILKSDNAFSIDL
                     LKEKIPQLILNNQVYFDTTNCQVDNNIKNLLLNHKLKSFAPTLHEMRLIKDKLEISTM
                     QKAANISIKAHQLAMQTIKPYMFEFEVQSIFDGFFTKNNAQHAYTPIVAGGMNSCLLH
                     YIENNKKLNKGDLILIDAGAEVDCYASDITRTLPVNGQFSSTQKQIYQIVLNAQINAI
                     NTIKPGIKINKPHKVATNTIKQGLIDLGILQINDDLSQFYMHSTGHWLGLDVHDVGQY
                     KKNGHHKKFVAGMITTIEPGIYIRKNDKINPIYHNIGVRIEDIVLVTTSGNTVLTKSL
                     AKEINDIELLMNR"
     misc_feature    complement(128015..128368)
                     /gene="pepP"
                     /locus_tag="COSY_0118"
                     /note="Aminopeptidase P, N-terminal domain; Region: AMP_N;
                     pfam05195"
                     /db_xref="CDD:218491"
     misc_feature    complement(127163..128365)
                     /gene="pepP"
                     /locus_tag="COSY_0118"
                     /note="proline aminopeptidase P II; Provisional; Region:
                     PRK10879"
                     /db_xref="CDD:182804"
     misc_feature    complement(127202..127903)
                     /gene="pepP"
                     /locus_tag="COSY_0118"
                     /note="Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro
                     dipeptidase, X-Pro dipeptidase, proline dipeptidase.,
                     imidodipeptidase, peptidase D, gamma-peptidase. Catalyses
                     hydrolysis of Xaa-Pro dipeptides; also acts on
                     aminoacyl-hydroxyproline analogs. No action on...; Region:
                     Prolidase; cd01087"
                     /db_xref="CDD:238520"
     misc_feature    complement(order(127247..127249,127316..127318,
                     127406..127408,127634..127636,127667..127669,
                     127718..127720))
                     /gene="pepP"
                     /locus_tag="COSY_0118"
                     /note="active site"
                     /db_xref="CDD:238520"
     gene            128425..129141
                     /locus_tag="COSY_0119"
                     /db_xref="GeneID:5171862"
     CDS             128425..129141
                     /locus_tag="COSY_0119"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218977.1"
                     /db_xref="GI:148244283"
                     /db_xref="GeneID:5171862"
                     /translation="MKHVRLYQNISLKINKKLVLDEYASCHLAKALRFLQGQEITLFN
                     GDGRNYLATIVRVKNYCEVEIHTCTHNNSESQLNITLVQGITKGEKMDFLTQKSVELG
                     VNRIIPIFSEYCVIHLQDEKLQKRMERWQKIIIGACEQSGRSVIPSLVLAMNFEDFVN
                     TKFGNGFILHHRAKYSLLEMNKVNQATIIIGPEGGLSDQEIANANEQGAQSLVLGSRI
                     LRAETASLATIANMQLLWGS"
     misc_feature    128437..129135
                     /locus_tag="COSY_0119"
                     /note="16S ribosomal RNA methyltransferase RsmE;
                     Provisional; Region: PRK11713"
                     /db_xref="CDD:236959"
     misc_feature    128461..129138
                     /locus_tag="COSY_0119"
                     /note="RNA methyltransferase, RsmE family; Region:
                     TIGR00046"
                     /db_xref="CDD:129157"
     gene            complement(129127..130185)
                     /locus_tag="COSY_0120"
                     /db_xref="GeneID:5172618"
     CDS             complement(129127..130185)
                     /locus_tag="COSY_0120"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218978.1"
                     /db_xref="GI:148244284"
                     /db_xref="GeneID:5172618"
                     /translation="MLNTEDILKLNVLIKTSIAIRIDTYKLIVVGLNTQFKEQMINLS
                     LTSDSDAYIKEVKELLINQVMGTMKGKYLSYLKHWSRIGQVTSSNLSLLLKLGEVEAV
                     IAVSNAIKFDKNLLKLTWWCATNTANQAEIGRLLLTKDFVINTNIGRNIAKYLLELLP
                     FIHDIEQLIDTTNLILQKGLINKTEKAKLWEQGQKKTAFLVGFIERMNLKDIYFKIHT
                     DINIISFNFKHQDLQLISNKQTQLLLKTTINILKKINQETILYRTLDVLGQYLYHPSI
                     TFKESIVDITNQANVMVCNIKDEREKLFARMLLAGVSERLVVSTISAHRLTGSAIRRK
                     LINILSPIQKALDVLTTP"
     gene            complement(130460..131287)
                     /gene="proC"
                     /locus_tag="COSY_0121"
                     /db_xref="GeneID:5172382"
     CDS             complement(130460..131287)
                     /gene="proC"
                     /locus_tag="COSY_0121"
                     /EC_number="1.5.1.2"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="YP_001218979.1"
                     /db_xref="GI:148244285"
                     /db_xref="GeneID:5172382"
                     /translation="MQNSLIGFIGAGNMTHAIISGLINNNTNHNQIKISDTNEALLLL
                     RKTEFNIEIFTDNTKLATQCSTIIFAVKPQVLSSVCKNLKNKLTTNTLIISIAAGVRS
                     HDIERWLGGNQAIIRTMPNTPALLNQGITGLFANKQVSNKQKFLAENILNSVGECLWV
                     NDEYLLNAITAVSGSGPAYFFLMLESMTKAGVTLGLDEVVAQKLSIQTALGASMMASR
                     SKDSPQQLRNKVTSKNGTTQAAIESLQNQDFEIIIAHAIRAASDKSNKIGIELSNDE"
     misc_feature    complement(130484..131278)
                     /gene="proC"
                     /locus_tag="COSY_0121"
                     /note="pyrroline-5-carboxylate reductase; Region:
                     PLN02688"
                     /db_xref="CDD:178291"
     misc_feature    complement(130478..131272)
                     /gene="proC"
                     /locus_tag="COSY_0121"
                     /note="pyrroline-5-carboxylate reductase; Reviewed;
                     Region: PRK11880"
                     /db_xref="CDD:237008"
     gene            131363..132031
                     /gene="gph"
                     /locus_tag="COSY_0122"
                     /db_xref="GeneID:5172482"
     CDS             131363..132031
                     /gene="gph"
                     /locus_tag="COSY_0122"
                     /EC_number="3.1.3.18"
                     /note="catalyzes the dephosphorylation of
                     2-phosphoglycolate to form glycolate and phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="YP_001218980.2"
                     /db_xref="GI:162329287"
                     /db_xref="GeneID:5172482"
                     /translation="MKTFNPKLIMIDLDGTLVDSVPDLAYCIDELMKAMNRTPWGEFK
                     VRDWVGNGVLKLVERSLTGELEASVNKQDFDKAYSIFLELYSINTSVRSCLYDGVKEG
                     LDYLKRQGYLLGCVTNKDEQFTLPILKDLDIFNYFGLVISGDTLVKKKPDPLPLLHSA
                     EFFNIPPQDCLMLGDSISDVIASRVAGFEIICMSYGYNHGKDIQDVNPDLVIDSMIEL
                     KDYL"
     misc_feature    131363..132028
                     /gene="gph"
                     /locus_tag="COSY_0122"
                     /note="phosphoglycolate phosphatase; Provisional; Region:
                     PRK13222"
                     /db_xref="CDD:237310"
     misc_feature    131621..131941
                     /gene="gph"
                     /locus_tag="COSY_0122"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    131711..131713
                     /gene="gph"
                     /locus_tag="COSY_0122"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     gene            132059..133297
                     /gene="bioA"
                     /locus_tag="COSY_0123"
                     /db_xref="GeneID:5171943"
     CDS             132059..133297
                     /gene="bioA"
                     /locus_tag="COSY_0123"
                     /EC_number="2.6.1.62"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine-8-amino-7-oxononanoate
                     aminotransferase"
                     /protein_id="YP_001218981.1"
                     /db_xref="GI:148244287"
                     /db_xref="GeneID:5171943"
                     /translation="MDTFDNQHIWHPYAKIPNEVPTYLVESAEGVYLILEGGNRVIDG
                     MSSWWSAIHGYNHPVLNKAIETQLRKMSHIMFGGLTHQPAIDLTKTLLSVTPDNLTKV
                     FFTDSGSLSVEVALKMVLQYWNNKHQANKQKFITIRGGYHGDTFGAMSVCDPDNGMHH
                     LFSSVLPQHFFVKSPSIVPMNEALEDLRVTLKQNSNKIAAMILEPVIQNAGGIRTYNP
                     QYLLKAKKLCKQNNILFVLDEIATGFGRTGELFALEYANVEPDILCLGKALTGGYITL
                     AATLTTDDVSNVVGTLMHGPTFMANPLACAVANASIELLLSSPWKNSIANIGKILSAE
                     LLPLKNHDKVKDVRILGAIGVIEITHEIDIQIVQKYLIDLGVWLRPYGKLLYTMPPFI
                     ITDDELLTITSAIKAIVSRL"
     misc_feature    132068..133285
                     /gene="bioA"
                     /locus_tag="COSY_0123"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     Region: OAT_like; cd00610"
                     /db_xref="CDD:99735"
     misc_feature    132083..133288
                     /gene="bioA"
                     /locus_tag="COSY_0123"
                     /note="adenosylmethionine-8-amino-7-oxononanoate
                     transaminase; Region: bioA; TIGR00508"
                     /db_xref="CDD:233000"
     misc_feature    order(132377..132385,132479..132484,132488..132490,
                     132668..132670,132770..132772,132776..132781,
                     132857..132859)
                     /gene="bioA"
                     /locus_tag="COSY_0123"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99735"
     misc_feature    order(132380..132385,132479..132484,132668..132670,
                     132770..132772,132779..132781,132857..132859)
                     /gene="bioA"
                     /locus_tag="COSY_0123"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99735"
     misc_feature    132857..132859
                     /gene="bioA"
                     /locus_tag="COSY_0123"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     gene            complement(134198..136240)
                     /gene="priA"
                     /locus_tag="COSY_0124"
                     /db_xref="GeneID:5172403"
     CDS             complement(134198..136240)
                     /gene="priA"
                     /locus_tag="COSY_0124"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="YP_001218982.1"
                     /db_xref="GI:148244288"
                     /db_xref="GeneID:5172403"
                     /translation="MIKYLFYQYSITLSLIIEVAISIPLSKTFNYLCDNEVSVGVRVK
                     VPLARKKVIGIVLAIKDKSRYNETNFRKKREDTLGYKLKSVEKVLDKIPILDKSILDL
                     LFWSANYYHYPISKVISYTLPKNLLLGKEAKIKKIIDFPNKLQQPDFQPTDEQNIAIE
                     QILKSTNQYHAFLLHGVTGSGKTEVYLHIIQSMIDQKKQVLVLVPEIGLTPQMITHFK
                     SRLKTRVIAIHSQLNETQKLDAYLMAKNGDAGVILGTRSAIFAPISNFGLIIIDEEHD
                     NSFKQQSSFRYSARNLGFIRAQQSNIPLVLGTATPSLELLKIAMDKKITRITLTKRAG
                     GATLPKVSLIDMRSNTNDALSKILIEKIKQYLSIDKQVMLFINRRGYAPIYYCTQCNW
                     KAQCNHCDSTMVYHRHINRLKCHHCGDEKIPEHVCPNCTKQSLKILGYGTEKLEETLY
                     SYFVDTPIIRIDRDTTRRKKSFAQHLEQINTGKPCIIIGTQMLTKGHDFSNLAMVGIL
                     DVDTGFLSTNFRATEYLAQLLIQVSGRAGRHKERGEVVIQTRYPDHPIFNFVLSSRYT
                     QFASQLLKQRLSAMMPPFSHQALLCANAKNKQNAENFLHEAAILLKSIQMNSVEIWGP
                     IANTIEKKSDYYYFNLYLQSNNRVTLHQILSTFSQHINKLKLKNKVRWYLDIDPIE"
     misc_feature    complement(134201..136195)
                     /gene="priA"
                     /locus_tag="COSY_0124"
                     /note="primosome assembly protein PriA; Validated; Region:
                     PRK05580"
                     /db_xref="CDD:235514"
     misc_feature    complement(135308..135727)
                     /gene="priA"
                     /locus_tag="COSY_0124"
                     /note="DEAD-like helicases superfamily. A diverse family
                     of proteins involved in ATP-dependent RNA or DNA
                     unwinding. This domain contains the ATP-binding region;
                     Region: DEXDc; cd00046"
                     /db_xref="CDD:238005"
     misc_feature    complement(135692..135706)
                     /gene="priA"
                     /locus_tag="COSY_0124"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238005"
     misc_feature    complement(135416..135427)
                     /gene="priA"
                     /locus_tag="COSY_0124"
                     /note="putative Mg++ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238005"
     misc_feature    complement(134621..>134815)
                     /gene="priA"
                     /locus_tag="COSY_0124"
                     /note="helicase superfamily c-terminal domain; Region:
                     HELICc; smart00490"
                     /db_xref="CDD:197757"
     gene            136268..136705
                     /locus_tag="COSY_0125"
                     /db_xref="GeneID:5171806"
     CDS             136268..136705
                     /locus_tag="COSY_0125"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218983.1"
                     /db_xref="GI:148244289"
                     /db_xref="GeneID:5171806"
                     /translation="MVIIQNNIHDLSVNEDDLSCILQKVVKEWGKGESELLVRLVDEA
                     EIQNLNKVYRYKDEPTNVLSFPTDLPIEIDEKILGDVVICIQIVLKESIEQHKSFNNH
                     LMHMAVHGTLHLLGYDHIDTKDAQNMANLERKILAKIGINNPY"
     misc_feature    136268..136702
                     /locus_tag="COSY_0125"
                     /note="metal-binding heat shock protein; Provisional;
                     Region: PRK00016"
                     /db_xref="CDD:234575"
     gene            complement(136759..137931)
                     /gene="mesJ"
                     /locus_tag="COSY_0126"
                     /db_xref="GeneID:5172613"
     CDS             complement(136759..137931)
                     /gene="mesJ"
                     /locus_tag="COSY_0126"
                     /note="tRNA(Ile)-lysidine synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle protein MesJ"
                     /protein_id="YP_001218984.1"
                     /db_xref="GI:148244290"
                     /db_xref="GeneID:5172613"
                     /translation="MENLKTKDLFLEDKNIVLGLSGGIDSIVLLHYLNTHYPNKIRVI
                     HCNHHLSQFCNKWDKFCKTTCLNLNIVYLSINLSFDNTSNIEENARKKRYHSLSNLLK
                     ENEVLCTAHHKNDQAETLLLQLFRGSGSAGLAAMPKEKPLGKGIHYRPFLTINKSQVS
                     DYANNHKLNWIEDDSNKNTYFRRNFLRLEILPKLSEVYKNLTETLARSAQHQSETLKL
                     TRELADIDIKTYYIINHTNRINISQLIKLGIHRIKNIIRHHLNLLNFLTPSDKIMHQI
                     IKLLHAKKDTKPLVCWNKYEVRRYKNELYFINKTLLKKNEPCPFHEELKDFPNFSIRY
                     RQKGQRIKLLEKKHTKSLKKVLQEANIPPWERNQLKMYYISNKLYAIERIGKTYSA"
     misc_feature    complement(136792..137901)
                     /gene="mesJ"
                     /locus_tag="COSY_0126"
                     /note="tRNA(Ile)-lysidine synthetase; Provisional; Region:
                     tilS; PRK10660"
                     /db_xref="CDD:182626"
     misc_feature    complement(137356..137886)
                     /gene="mesJ"
                     /locus_tag="COSY_0126"
                     /note="N-terminal domain of predicted ATPase of the
                     PP-loop faimly implicated in cell cycle control [Cell
                     division and chromosome partitioning]. This is a subfamily
                     of Adenine nucleotide alpha hydrolases
                     superfamily.Adeninosine nucleotide alpha hydrolases...;
                     Region: PP-ATPase; cd01992"
                     /db_xref="CDD:238950"
     misc_feature    complement(order(137791..137793,137797..137799,
                     137854..137865,137869..137877))
                     /gene="mesJ"
                     /locus_tag="COSY_0126"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238950"
     misc_feature    complement(137014..137217)
                     /gene="mesJ"
                     /locus_tag="COSY_0126"
                     /note="TilS substrate binding domain; Region: TilS;
                     pfam09179"
                     /db_xref="CDD:204159"
     misc_feature    complement(<136777..136941)
                     /gene="mesJ"
                     /locus_tag="COSY_0126"
                     /note="TilS substrate C-terminal domain; Region: TilS_C;
                     pfam11734"
                     /db_xref="CDD:221192"
     gene            complement(137912..138880)
                     /gene="accA"
                     /locus_tag="COSY_0127"
                     /db_xref="GeneID:5172227"
     CDS             complement(137912..138880)
                     /gene="accA"
                     /locus_tag="COSY_0127"
                     /EC_number="6.4.1.2"
                     /note="catalyzes the carboxylation of acetyl-CoA to
                     malonyl-CoA; forms a tetramer composed of two alpha (AccA)
                     and two beta (AccD) subunits; one of the two catalytic
                     subunits that can form the acetyl CoA carboxylase enzyme
                     together with a carrier protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="YP_001218985.1"
                     /db_xref="GI:148244291"
                     /db_xref="GeneID:5172227"
                     /translation="MNLDYLDFEQPIAELEEKIQTLDNIKGKANIKDKADIINKIKAL
                     KSKSNALTKKIFSSLSDWQISQLARHPKRLYTLDYISDVFDEFTELHGDRTYGDDHAI
                     IGGIATLDNQPVMFIGQQKGRTTQEKIKYNFGMPRPEGYRKALRLMKLAEKFSMPIVT
                     FIDTPGAYPGIGAEERGQSEAIAKNLFEMSTLPTPIISIVIGEGGSGGALAIGVADII
                     MMFEYSIYSVISPEGCASILYKDVTKANLAAESLKLTSIHLKKERLIDVVINEPLGGI
                     HRNPSQAKVLLKEVLTQQLNKIKQLPIEQLLQNRQKKLLGFGKFKD"
     misc_feature    complement(137915..138880)
                     /gene="accA"
                     /locus_tag="COSY_0127"
                     /note="acetyl-CoA carboxylase carboxyltransferase subunit
                     alpha; Validated; Region: PRK05724"
                     /db_xref="CDD:235580"
     misc_feature    complement(137915..138880)
                     /gene="accA"
                     /locus_tag="COSY_0127"
                     /note="acetyl-CoA carboxylase carboxyltransferase alpha
                     subunit; Provisional; Region: accA; CHL00198"
                     /db_xref="CDD:214393"
     gene            139149..139346
                     /locus_tag="COSY_0128"
                     /db_xref="GeneID:5172275"
     CDS             139149..139346
                     /locus_tag="COSY_0128"
                     /codon_start=1
                     /transl_table=11
                     /product="cbb3-type cytochrome oxidase maturation protein"
                     /protein_id="YP_001218986.1"
                     /db_xref="GI:148244292"
                     /db_xref="GeneID:5172275"
                     /translation="MDVIYWLVPSMIFVGIVLVIILIIGVKNGQFDDLEGEGQRILYD
                     EEQMNLAPIKNIKNKVDNSSF"
     misc_feature    139152..139286
                     /locus_tag="COSY_0128"
                     /note="Cytochrome oxidase maturation protein cbb3-type;
                     Region: CcoS; pfam03597"
                     /db_xref="CDD:202697"
     gene            139384..140061
                     /locus_tag="COSY_0129"
                     /db_xref="GeneID:5172622"
     CDS             139384..140061
                     /locus_tag="COSY_0129"
                     /note="Similar to phosphate transport regulator PhoU."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218987.1"
                     /db_xref="GI:148244293"
                     /db_xref="GeneID:5172622"
                     /translation="MAQNIIDGLFGKSPISSLQKHMTQVHSCISELNGFMIAIHTQNW
                     VKAEIIRSDIDTKEGKADILKKNLRLSLSSTFMMPFSRRDLLDLLLIQDSIANITKDV
                     SGLMINRKMILPDETFDDVIELTKVCIKTSSTALKAVNELDELLETAFGSRERKIISS
                     IIEDINELESKSDKIQHEIRAELFPLESSLPPVDIMFYYRTVEWLGELADAAQKVGSR
                     LEVLLAR"
     misc_feature    139393..140058
                     /locus_tag="COSY_0129"
                     /note="Phosphate transport regulator (distant homolog of
                     PhoU) [Inorganic ion transport and metabolism]; Region:
                     COG1392"
                     /db_xref="CDD:224310"
     gene            140073..141353
                     /gene="pitA"
                     /locus_tag="COSY_0130"
                     /db_xref="GeneID:5172589"
     CDS             140073..141353
                     /gene="pitA"
                     /locus_tag="COSY_0130"
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+):phosphate symporter"
                     /protein_id="YP_001218988.1"
                     /db_xref="GI:148244294"
                     /db_xref="GeneID:5172589"
                     /translation="MDIIANYADIFIMLSIGFGLFMAWGIGANDVSNAMGTSVGSAAI
                     TFKQAVVIAVIFEFSGAILAGGEVTDTVRKGILDAVLFTNNPHLLVYGMLASLLAAGA
                     WLLIASSLGWPVSTTHSIVGAIVGFGAVGVGIDAVAWDKVIKIVMSWVVSPVLAGTLA
                     VFIFKSLQFLVIDTKDPLINAKRYLPFYVFFVGFIIALVTQFKGLKHIDSLKYISKNV
                     SLSLIIAIIVGIFAAVIAAFIMRNIKINPKDDKDFHYANMEKLFAVLMVITASAMAFA
                     HGSNDVANAIGPLAAVYSIVEAGGDITSRSAIPSWVLLVGGGGIIFGFVTYGFKVMKT
                     IGQGITELTPSRGFAAELAAATTVVLASSTGIPVSTTQVLVGAVLGVGIARGVVALNM
                     RVINTIFLSWLITLPAGAVMSILFFFALKGVFGA"
     misc_feature    140097..>140624
                     /gene="pitA"
                     /locus_tag="COSY_0130"
                     /note="Phosphate/sulphate permeases [Inorganic ion
                     transport and metabolism]; Region: PitA; COG0306"
                     /db_xref="CDD:223383"
     misc_feature    <140835..141344
                     /gene="pitA"
                     /locus_tag="COSY_0130"
                     /note="Phosphate/sulphate permeases [Inorganic ion
                     transport and metabolism]; Region: PitA; COG0306"
                     /db_xref="CDD:223383"
     gene            141357..141587
                     /locus_tag="COSY_0131"
                     /db_xref="GeneID:5172323"
     CDS             141357..141587
                     /locus_tag="COSY_0131"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218989.1"
                     /db_xref="GI:148244295"
                     /db_xref="GeneID:5172323"
                     /translation="MTLEEIKEKIELGIENSTVIMEGDGCSCSTKVISPIFEGMSLLA
                     RQKMVLAVMNKEIINGTLHALSIKTRTPEEDT"
     misc_feature    <141423..141578
                     /locus_tag="COSY_0131"
                     /note="BolA-like protein; Region: BolA; pfam01722"
                     /db_xref="CDD:216662"
     gene            141728..142996
                     /gene="rhlE"
                     /locus_tag="COSY_0132"
                     /db_xref="GeneID:5172115"
     CDS             141728..142996
                     /gene="rhlE"
                     /locus_tag="COSY_0132"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="YP_001218990.1"
                     /db_xref="GI:148244296"
                     /db_xref="GeneID:5172115"
                     /translation="MSFSKLGLSDSILKAIEQKGYSEPSPIQNQSIPAILNGKDVMAA
                     AQTGTGKTACFALPILEILSKKKPTKSNQVRTLILTPTRELAIQVSDSVTTYGKYLPL
                     KSSVVFGGVKINPQMQRLCSGVDILVATPGRLLDLYSQNSVKFDMLEIVVFDEADRML
                     DMGFINDIKRILKILPSKKQTLMFSATFSNKILTLAKSLVNNPVEISVTPRNSTVKAI
                     KQWIHPVDKSKKHALLTHLIQEHNWHQVLVFSRTKYGANRIVNQLEKKKIRATAIHSN
                     KSQGARTRALLDFKNHEVNVLVATDIAARGIEINQLPHVINFDLPYVPEDYVHRIGRT
                     GRAGSKGEAISLVSADEAKQLFDVECLIQNKLDRVMVEGFVPDHNLPESGKKLLSPKN
                     RNFKNSKSRNRLRYGKNSSFKKINLTMKNS"
     misc_feature    141734..142348
                     /gene="rhlE"
                     /locus_tag="COSY_0132"
                     /note="DEAD-box helicases. A diverse family of proteins
                     involved in ATP-dependent RNA unwinding, needed in a
                     variety of cellular processes including splicing, ribosome
                     biogenesis and RNA degradation. The name derives from the
                     sequence of the Walker  B motif; Region: DEADc; cd00268"
                     /db_xref="CDD:238167"
     misc_feature    141773..142390
                     /gene="rhlE"
                     /locus_tag="COSY_0132"
                     /note="DEAD-like helicases superfamily; Region: DEXDc;
                     smart00487"
                     /db_xref="CDD:214692"
     misc_feature    141869..141883
                     /gene="rhlE"
                     /locus_tag="COSY_0132"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238167"
     misc_feature    142187..142198
                     /gene="rhlE"
                     /locus_tag="COSY_0132"
                     /note="Mg++ binding site [ion binding]; other site"
                     /db_xref="CDD:238167"
     misc_feature    142280..142288
                     /gene="rhlE"
                     /locus_tag="COSY_0132"
                     /note="motif III; other site"
                     /db_xref="CDD:238167"
     misc_feature    142379..142765
                     /gene="rhlE"
                     /locus_tag="COSY_0132"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:238034"
     misc_feature    order(142478..142489,142547..142552,142625..142633)
                     /gene="rhlE"
                     /locus_tag="COSY_0132"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:238034"
     misc_feature    order(142649..142651,142712..142714,142724..142726,
                     142733..142735)
                     /gene="rhlE"
                     /locus_tag="COSY_0132"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238034"
     gene            143007..143252
                     /locus_tag="COSY_0133"
                     /db_xref="GeneID:5172448"
     CDS             143007..143252
                     /locus_tag="COSY_0133"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218991.1"
                     /db_xref="GI:148244297"
                     /db_xref="GeneID:5172448"
                     /translation="MKIKLITFVIVLFLTPVHAGLWEKITTIGAKIVTPTSEYLIETS
                     GWNIRVYEWIPTDNPNTRCLFAAGSQKGGVACYSIND"
     gene            complement(144020..145204)
                     /gene="tyrS"
                     /locus_tag="COSY_0134"
                     /db_xref="GeneID:5172003"
     CDS             complement(144020..145204)
                     /gene="tyrS"
                     /locus_tag="COSY_0134"
                     /EC_number="6.1.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosyl-tRNA synthetase"
                     /protein_id="YP_001218992.1"
                     /db_xref="GI:148244298"
                     /db_xref="GeneID:5172003"
                     /translation="MNIEQTLAIFTRGTNEILPFHELKEKLKKDKPLRIKAGFDPTTP
                     DLHLGHTVVINKLKQLQNLGHEILFLIGDFTAMIGDPTGKSKTRPPLSKKQVQENAKS
                     YTKQIFKILDKNKTKVVFNFQWMDKMKPIEFIQLASKQTIARILERDDFSKRYKSGQS
                     ISTHEFLYPLIQGNDSVELQSDVEVGGTDQKFNLLVGRELQKQAGQEQQVILTMPILE
                     GLDGVQKMSKSLDNYIGINALPDEMFGKIMSISDDLMWRYFELLSFQSLEAITNLKQT
                     IVQGKNPRDIKFVLANEIVTRFYKVDVAKEAQQNFINRFSKNQTPNKMNEFSFKAGIK
                     IANLLKDTGLCFSTSNAYQMIKQGGVKINNIKITNKNFEPPTNTNVYQVGKRKFARVT
                     IQ"
     misc_feature    complement(144026..145204)
                     /gene="tyrS"
                     /locus_tag="COSY_0134"
                     /note="tyrosyl-tRNA synthetase; Validated; Region:
                     PRK05912"
                     /db_xref="CDD:235645"
     misc_feature    complement(144314..145096)
                     /gene="tyrS"
                     /locus_tag="COSY_0134"
                     /note="catalytic core domain of tyrosinyl-tRNA synthetase;
                     Region: TyrRS_core; cd00805"
                     /db_xref="CDD:173902"
     misc_feature    complement(order(144521..144532,144554..144559,
                     144635..144637,144644..144649,144653..144655,
                     144680..144682,144689..144691,144701..144703,
                     145055..145060,145064..145066,145085..145093))
                     /gene="tyrS"
                     /locus_tag="COSY_0134"
                     /note="active site"
                     /db_xref="CDD:173902"
     misc_feature    complement(145055..145066)
                     /gene="tyrS"
                     /locus_tag="COSY_0134"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173902"
     misc_feature    complement(order(144692..144697,144704..144709,
                     144713..144715,144767..144772,144776..144787,
                     144791..144796,144800..144808,144812..144817,
                     144971..144976,144983..144985))
                     /gene="tyrS"
                     /locus_tag="COSY_0134"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:173902"
     misc_feature    complement(144518..144532)
                     /gene="tyrS"
                     /locus_tag="COSY_0134"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173902"
     gene            complement(145210..146469)
                     /gene="proA"
                     /locus_tag="COSY_0135"
                     /db_xref="GeneID:5171869"
     CDS             complement(145210..146469)
                     /gene="proA"
                     /locus_tag="COSY_0135"
                     /EC_number="1.2.1.41"
                     /note="Catalyzes the phosphorylation of L-glutamate during
                     the proline biosynthesis pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl phosphate reductase"
                     /protein_id="YP_001218993.1"
                     /db_xref="GI:148244299"
                     /db_xref="GeneID:5171869"
                     /translation="MDSIKNLITLLGENAKNAAKTLRGATTVAKNNALINIANQIDQN
                     RRSILKANKKDLANSKNKGLNIALLDRLMLDNIRINNIIKSLNQIANLPDPIGEITDL
                     KYQASGIQVGKMRVSLGVIGVIYESRPNVTIDAVALCLKSGNSIILRGGSETVHSNHA
                     LYTCVKQSITQAGLNENCAQLINTQDRKAVIELVKASDYVDAIIPRGGKGLLKAISNS
                     AKVPIIKHLDGICHTYIDKDADTQKAISIAFNAKTRRYGVCNATETLLVHSSVVGKIL
                     PELIAQYLAKGVELRGCPETVKLSNTIILATAEDWKTEYLDAILSIRIVKSMSEAIKH
                     IDKYSSNHTESIVSENYTRSRRFITEVNSSSVMINASTSFADGFEYGLGGEIGISTDK
                     LHVRGPVGLEGLTSQKFIVLGNGHIRQ"
     misc_feature    complement(145228..146439)
                     /gene="proA"
                     /locus_tag="COSY_0135"
                     /note="Gamma-glutamyl phosphate reductase (GPR), aldehyde
                     dehydrogenase families 18 and 19; Region:
                     ALDH_F18-19_ProA-GPR; cd07079"
                     /db_xref="CDD:143398"
     misc_feature    complement(145246..146427)
                     /gene="proA"
                     /locus_tag="COSY_0135"
                     /note="gamma-glutamyl phosphate reductase; Region: proA;
                     TIGR00407"
                     /db_xref="CDD:161862"
     misc_feature    complement(145693..145695)
                     /gene="proA"
                     /locus_tag="COSY_0135"
                     /note="putative catalytic cysteine [active]"
                     /db_xref="CDD:143398"
     gene            complement(146457..147476)
                     /gene="holA"
                     /locus_tag="COSY_0136"
                     /db_xref="GeneID:5172487"
     CDS             complement(146457..147476)
                     /gene="holA"
                     /locus_tag="COSY_0136"
                     /EC_number="2.7.7.7"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III delta subunit"
                     /protein_id="YP_001218994.1"
                     /db_xref="GI:148244300"
                     /db_xref="GeneID:5172487"
                     /translation="MKIKPQQLNTQLANKLDAIYFIFGAEILLIEQSLAQIKKAAKQK
                     KFDEKVSFEIDSNFDWNQIFEEISTTSLFSPKRIIECRLKTGKIGIKGANNLVEIVNT
                     LPNNILLIVSTGKLNIAQQKSKWFKILEQTGSLIQHFEVQNNHLVDWITKQMAELGLK
                     DNIEIAQNIAFCTEGNLTASMQAIQKLKIAYPNGKINTQEYLKQANQQSKYTVYDLID
                     AALFGNSNQVNKIYQTLISNTIMPIQLSHALYLEIKSITEMSIELRQVKDTNIVLKNH
                     QVWNTRKPIITNALKHHSYQHFQKILLSLGCIDRSIKNMDNLNVIDELHTLLLSLAGE
                     IQWTQ"
     misc_feature    complement(146478..147476)
                     /gene="holA"
                     /locus_tag="COSY_0136"
                     /note="DNA polymerase III subunit delta; Reviewed; Region:
                     holA; PRK05574"
                     /db_xref="CDD:235511"
     misc_feature    complement(146910..147419)
                     /gene="holA"
                     /locus_tag="COSY_0136"
                     /note="DNA polymerase III, delta subunit; Region:
                     DNA_pol3_delta; pfam06144"
                     /db_xref="CDD:218910"
     gene            complement(147466..147912)
                     /locus_tag="COSY_0137"
                     /db_xref="GeneID:5172695"
     CDS             complement(147466..147912)
                     /locus_tag="COSY_0137"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218995.1"
                     /db_xref="GI:148244301"
                     /db_xref="GeneID:5172695"
                     /translation="MLKINLLAIMVTILSSCGFHTPYTNSTINASITSNRNNIFANEL
                     QKHFNQNMHKILVIQVGTENQNQRTVSYTSSNEASSYTLNLNIPIKVFNHNKKLLLSK
                     TFSANTYLNKIDAYQANRLQIEEGYQQLRRLIIRQLLRRLYKLNEN"
     misc_feature    complement(<147589..147837)
                     /locus_tag="COSY_0137"
                     /note="Lipopolysaccharide-assembly; Region: LptE; cl01125"
                     /db_xref="CDD:242317"
     gene            148068..149990
                     /gene="ftsH"
                     /locus_tag="COSY_0138"
                     /db_xref="GeneID:5172113"
     CDS             148068..149990
                     /gene="ftsH"
                     /locus_tag="COSY_0138"
                     /note="ATP-dependent Zn protease"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsH"
                     /protein_id="YP_001218996.1"
                     /db_xref="GI:148244302"
                     /db_xref="GeneID:5172113"
                     /translation="MFKNLLLWLILGGVLTSIFSQSQMGDQKNDITYSQFIQNVKQGA
                     VSQVTIAGSNITGVGTNGEQFATYSPGDLGLMGDLLNNGVNVVAKSPEKEGFFKQLII
                     SLAPILLLIGVVLYTMKGAGGAMGGKNPMSFGKSKARLITKDESNITFDDVAGVDEAK
                     DDVSELVDFLSDPGKFTKVGGKIPKGVLLVGPPGTGKTLLAKAIAGEADVPFFFISGS
                     DFVEMFVGVGASRVRDMFEQAKKNAPCIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQ
                     MLVEMDGFEGSEGVIVIAATNRPDVLDPALLRPGRFDRQVIVGLPDINGRNAILKIHM
                     RKLPIAKNVKSINIAKGTPGFSGADLANLTNEAALIAASKDKKLVGMQEFEKAKDKIM
                     MGSERKSMAMDESEKEMTAYHEAGHAIVGRLVPEHDPVYKVSIIPRGRALGVTMFLPE
                     KDSYSISKRKLNSQVASLFGGRIAEELIYGVDRVTTGASNDIERATEIAHKMVKQWGM
                     SEVLGPLSYGEDEGEVFLGRQVTKHKHISEDTFRTIDSEIRKIIDSNYQIAFKILKGN
                     KDILFEMTRALMEFETIDKEQIDDLMNRKPIRESAVVIDSNVASTELGSGATFDGSNQ
                     NSDEKPLNKGSTEQVA"
     misc_feature    148119..>148277
                     /gene="ftsH"
                     /locus_tag="COSY_0138"
                     /note="FtsH Extracellular; Region: FtsH_ext; pfam06480"
                     /db_xref="CDD:219052"
     misc_feature    148458..149846
                     /gene="ftsH"
                     /locus_tag="COSY_0138"
                     /note="ATP-dependent metalloprotease FtsH; Region:
                     FtsH_fam; TIGR01241"
                     /db_xref="CDD:233327"
     misc_feature    148617..149027
                     /gene="ftsH"
                     /locus_tag="COSY_0138"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    148638..148661
                     /gene="ftsH"
                     /locus_tag="COSY_0138"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(148641..148664,148815..148817,148956..148958)
                     /gene="ftsH"
                     /locus_tag="COSY_0138"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    148803..148820
                     /gene="ftsH"
                     /locus_tag="COSY_0138"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    148998..149000
                     /gene="ftsH"
                     /locus_tag="COSY_0138"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    149208..149840
                     /gene="ftsH"
                     /locus_tag="COSY_0138"
                     /note="Peptidase family M41; Region: Peptidase_M41;
                     pfam01434"
                     /db_xref="CDD:216502"
     gene            150026..150829
                     /gene="folP"
                     /locus_tag="COSY_0139"
                     /db_xref="GeneID:5171896"
     CDS             150026..150829
                     /gene="folP"
                     /locus_tag="COSY_0139"
                     /EC_number="2.5.1.15"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="YP_001218997.1"
                     /db_xref="GI:148244303"
                     /db_xref="GeneID:5171896"
                     /translation="MHSSNVMIMGVLNITPDSFSDGNQYFTVDRAINYAKLMIDQGAD
                     IIDIGGESTRPNALQVSIDDEINRVIPVIKVLSKLGSVPISIDTSQAKIMQLAIEAGV
                     SMINDVRALQAKSSLEVVASSNKDVCLMHMKGSPKTMQNNPIYTDVIDEIKYFFDQRI
                     EDCISAGIDQNKIILDPGFGFGKTLNHNFEILRRLDEFQSFGLRILVGMSRKSMIGNI
                     LNNRNIDGRMIGSVTTAIIAFQNGANIVRVHDVLDTKDAFKILQSVVGD"
     misc_feature    150041..150811
                     /gene="folP"
                     /locus_tag="COSY_0139"
                     /note="DHPS subgroup of Pterin binding enzymes. DHPS
                     (dihydropteroate synthase), a functional homodimer,
                     catalyzes the condensation of p-aminobenzoic acid (pABA)
                     in the de novo biosynthesis of folate, which is an
                     essential cofactor in both nucleic acid and...; Region:
                     DHPS; cd00739"
                     /db_xref="CDD:238380"
     misc_feature    150044..150817
                     /gene="folP"
                     /locus_tag="COSY_0139"
                     /note="dihydropteroate synthase; Region: DHPS; TIGR01496"
                     /db_xref="CDD:233439"
     misc_feature    order(150062..150064,150284..150286,150341..150343,
                     150347..150349,150413..150415,150551..150553,
                     150647..150649,150659..150661,150764..150766,
                     150770..150772)
                     /gene="folP"
                     /locus_tag="COSY_0139"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238380"
     misc_feature    order(150590..150592,150602..150607,150722..150724,
                     150734..150736,150746..150748,150791..150796)
                     /gene="folP"
                     /locus_tag="COSY_0139"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238380"
     misc_feature    150653..150661
                     /gene="folP"
                     /locus_tag="COSY_0139"
                     /note="inhibitor binding site; inhibition site"
                     /db_xref="CDD:238380"
     gene            150831..152156
                     /gene="glmM"
                     /locus_tag="COSY_0140"
                     /db_xref="GeneID:5171996"
     CDS             150831..152156
                     /gene="glmM"
                     /locus_tag="COSY_0140"
                     /EC_number="5.4.2.10"
                     /note="catalyzes the conversion of glucosamine-6-phosphate
                     to glucosamine-1-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="YP_001218998.1"
                     /db_xref="GI:148244304"
                     /db_xref="GeneID:5171996"
                     /translation="MDNYFGTDGIRGKVGIEPITADFFLKLGWSVGSVLAQQGKASVI
                     IGKDTRISGYLFESALEAGFLSAGVDVGLLGPMPTPAVAYLTQTYNANAGVVISASHN
                     HFQDNGVKFFSAKGLKFSSQDQSAIENKLTKPMINVGADKIGKAYRHEQPLGRYIEFC
                     KSTFDRTQSLLGLNIIIDCANGATYHIARSVFSELGANIHIINNTPDGFNINERCGAT
                     NTKHLQQVVLELKADLGIAFDGDGDRLIMVDENGELVDGDELIFIIAKAWQSQGRLVN
                     NTVVGTKMSNLGMRYALRDLNIQFIEVNVGDRFVMEQMQKSGSILGGEGSGHIICLNK
                     TTSGDGMISALQVLEVLVKSQSSLTQLKQSMNKYTQILINIKIQTQVNLENHTKLQQA
                     QLEVEKMLGSEGRVVIRASGTESLIRIMVEAKNKIIAKKGAKKLSNVFK"
     misc_feature    150840..152096
                     /gene="glmM"
                     /locus_tag="COSY_0140"
                     /note="GlmM is a bacterial phosphoglucosamine mutase
                     (PNGM) that belongs to the alpha-D-phosphohexomutase
                     superfamily. It is required for the interconversion of
                     glucosamine-6-phosphate and glucosamine-1-phosphate in the
                     biosynthetic pathway of...; Region: GlmM; cd05802"
                     /db_xref="CDD:100095"
     misc_feature    150840..152096
                     /gene="glmM"
                     /locus_tag="COSY_0140"
                     /note="phosphoglucosamine mutase; Provisional; Region:
                     glmM; PRK10887"
                     /db_xref="CDD:236787"
     misc_feature    order(150846..150848,150852..150854,150861..150863,
                     151128..151136,151158..151160,151545..151547,
                     151551..151553,151557..151562,151680..151682,
                     151743..151751,151800..151802,151806..151808,
                     151812..151814,152055..152057,152061..152069,
                     152082..152084)
                     /gene="glmM"
                     /locus_tag="COSY_0140"
                     /note="active site"
                     /db_xref="CDD:100095"
     misc_feature    order(150852..150854,151128..151130,151560..151562,
                     151680..151682,151743..151745,151749..151751,
                     151800..151802,151806..151808,151812..151814,
                     152055..152057,152061..152069,152082..152084)
                     /gene="glmM"
                     /locus_tag="COSY_0140"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100095"
     misc_feature    order(151128..151130,151545..151547,151551..151553,
                     151557..151559)
                     /gene="glmM"
                     /locus_tag="COSY_0140"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:100095"
     gene            153232..153975
                     /locus_tag="COSY_0141"
                     /db_xref="GeneID:5172014"
     CDS             153232..153975
                     /locus_tag="COSY_0141"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001218999.1"
                     /db_xref="GI:148244305"
                     /db_xref="GeneID:5172014"
                     /translation="MRSMYFSNTELFLISLIFLWVGFVRTGFGFGGVSLGLPLMLLIG
                     SSPVYWLPIIGIHLLFFSSLTLFKSIKEVDWCYLKYSLLWIIPPTLFGLFWLLSLSDK
                     VMIVFVYSITIFYSIIWIFNQKLTSYRVWVDKLLLILGGYVTGTSLIGAPLIVAVYIR
                     YVAKKYLRNTLFVLWFILVSIKMSVFIAFGIKIDWQLSLSLIPIAAIGHVVGLKLHQR
                     IIENDDLFRHWVGGILLLISLIGILKVVM"
     gene            154174..154749
                     /gene="rnfA"
                     /locus_tag="COSY_0142"
                     /db_xref="GeneID:5172134"
     CDS             154174..154749
                     /gene="rnfA"
                     /locus_tag="COSY_0142"
                     /note="Similar to Na(+)-translocating NADH-quinone
                     reductase subunit E."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex protein RnfA"
                     /protein_id="YP_001219000.1"
                     /db_xref="GI:148244306"
                     /db_xref="GeneID:5172134"
                     /translation="MNEYVLILVSTILVNNFVLVKFLGLCPFMGASRNIDTAIGMGFA
                     TTFVLTLASISSYLINTYVLVPFEMEYLRTIAFIVTIAGVVGFTELVVNKTSPTLYQS
                     LGVFLPLITTNCAVLGVALLNVNQDNGFLASGVYGFGVAIGFSFVLVLFSTIRERIDV
                     ADVPLTFKGVPIALITAGLMSMAFMGFIGLV"
     misc_feature    154174..154746
                     /gene="rnfA"
                     /locus_tag="COSY_0142"
                     /note="electron transport complex protein RsxA;
                     Provisional; Region: PRK05151"
                     /db_xref="CDD:235352"
     gene            154756..155301
                     /gene="rnfB"
                     /locus_tag="COSY_0143"
                     /db_xref="GeneID:5172560"
     CDS             154756..155301
                     /gene="rnfB"
                     /locus_tag="COSY_0143"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex protein RnfB"
                     /protein_id="YP_001219001.1"
                     /db_xref="GI:148244307"
                     /db_xref="GeneID:5172560"
                     /translation="MSLFDSVLIFSVFTLILGLILGYAGVKFKLKDNPLVNQIDTILP
                     QIQCGQCDYPGCRPYACAIASGEAKINQCPPGGQEVADALAELLGVETLELNAEHGET
                     KPSHVVFVDEQACIGCTLCIQACPVDAFVGASKMMTQVIINECTGCDLCIPVCPVDCI
                     YVKEITPNLITFVSDIIKVKH"
     misc_feature    154774..155235
                     /gene="rnfB"
                     /locus_tag="COSY_0143"
                     /note="electron transport complex, RnfABCDGE type, B
                     subunit; Region: rnfB; TIGR01944"
                     /db_xref="CDD:233648"
     misc_feature    154879..154983
                     /gene="rnfB"
                     /locus_tag="COSY_0143"
                     /note="Putative Fe-S cluster; Region: FeS; pfam04060"
                     /db_xref="CDD:112857"
     misc_feature    <155074..155241
                     /gene="rnfB"
                     /locus_tag="COSY_0143"
                     /note="RPB11 and RPB3 subunits of RNA polymerase; Region:
                     RNAP_RPB11_RPB3; cl11409"
                     /db_xref="CDD:245605"
     gene            155304..156794
                     /gene="rnfC"
                     /locus_tag="COSY_0144"
                     /db_xref="GeneID:5172574"
     CDS             155304..156794
                     /gene="rnfC"
                     /locus_tag="COSY_0144"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex protein RnfC"
                     /protein_id="YP_001219002.1"
                     /db_xref="GI:148244308"
                     /db_xref="GeneID:5172574"
                     /translation="MSNYSFKGGIVIKNPYLVNKVEIIQASLPKKIILPLQKFDGKAK
                     PCVSVGDYVLVGQVVASTESGFDVSSHASISGVVLSIDTQDIVHKSGFKFQCITIKSD
                     GEDKWIDNKGGNVDFLHYSKETLVGIIQKSGIVGMGGAGFPTHVKINKVLDCHTLIIN
                     GTECEPGVMCDDALMQFYPKEIILGIEILLYICGADRAIIAIEDDKQAAYQALLTVNR
                     NDRININQIPTKYTSGAEKLLIKALLDIEILSGGFAINEGIICQNISTTKAVFDAVIN
                     HKPLVSRIVTVTGDGVYPNNFEVRLGASFEHLISMTSPNTKEHNYRMGGMMMGIDVVD
                     INMPIGKTTSAIFVNNKVSEPIVQECIRCGQCSEVCPIGLLPQQLYWYIKSKNFEKAL
                     NYNLPDCIECACCDYVCPSHIPLVSYFSFAKTFSKQQTIEQNKVNTARERFKYREYRL
                     ERNKLERAQVMLDKKKALKEKMAKEQFQKQKITEAIQRVKQAKDKI"
     misc_feature    155313..156575
                     /gene="rnfC"
                     /locus_tag="COSY_0144"
                     /note="electron transport complex, RnfABCDGE type, C
                     subunit; Region: rnfC; TIGR01945"
                     /db_xref="CDD:233649"
     misc_feature    156153..>156236
                     /gene="rnfC"
                     /locus_tag="COSY_0144"
                     /note="SLBB domain; Region: SLBB; pfam10531"
                     /db_xref="CDD:220798"
     misc_feature    <156372..>156569
                     /gene="rnfC"
                     /locus_tag="COSY_0144"
                     /note="The HCP family of iron-sulfur proteins includes
                     hybrid cluster protein (HCP), acetyl-CoA synthase (ACS),
                     and carbon monoxide dehydrogenase (CODH), all of which
                     contain [Fe4-S4] metal clusters at their active sites.
                     These proteins have a conserved...; Region: HCP_like;
                     cl14655"
                     /db_xref="CDD:246686"
     gene            156791..157735
                     /gene="rnfD"
                     /locus_tag="COSY_0145"
                     /db_xref="GeneID:5172729"
     CDS             156791..157735
                     /gene="rnfD"
                     /locus_tag="COSY_0145"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex protein RnfD"
                     /protein_id="YP_001219003.1"
                     /db_xref="GI:148244309"
                     /db_xref="GeneID:5172729"
                     /translation="MTLILSSTSWMMRQVIYALALGIVVSYYFFGWGIVLQIVLGVIT
                     AVAVESAFLAFRGRDIISSISDGSIILTAILLAISIPNIAPWWVIIVGISFAIIFGKQ
                     LYGGLGNNLFNPAMLGYVFLLISYPLQMSTWPINFLSFDQALEVVFNLSNIDAISGAT
                     RLDEIKNSLSLSNSIKQLEIHFPSQVWINVGFFFGGLYLLFRKIISWHIPVSFLVGIV
                     ITSVLLWISNVDLYIPMQNHIMLGGTMLGAFFIATDPVSASTTINGRIIYGFLIGVLI
                     VIIRTFGGYPDGIAFAVLLMNMTVPLIDVYTQPKVFGQ"
     misc_feature    156809..157729
                     /gene="rnfD"
                     /locus_tag="COSY_0145"
                     /note="NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE;
                     cl00779"
                     /db_xref="CDD:242085"
     gene            157738..158343
                     /gene="rnfG"
                     /locus_tag="COSY_0146"
                     /db_xref="GeneID:5172526"
     CDS             157738..158343
                     /gene="rnfG"
                     /locus_tag="COSY_0146"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex protein RnfG"
                     /protein_id="YP_001219004.1"
                     /db_xref="GI:148244310"
                     /db_xref="GeneID:5172526"
                     /translation="MRVILKSGALLFVFTVVSIFFVSLTQIKTKDIIIYNEKQLLIQR
                     LGELVSGYSNDILLDKYSKTLKLHGILQNINIYPVKKNHQIFSYLIEHTYPNGYNGDI
                     RLLTGVGIDKKLLGVRVIMHKETPGLGDKIELKKSNWIEQFFGLSLLNPVKKNWKVKR
                     DGGIFDTFTGATITPRAIVTATYQVLELLNEPCILSKKPCN"
     misc_feature    157822..158340
                     /gene="rnfG"
                     /locus_tag="COSY_0146"
                     /note="FMN-binding domain; Region: FMN_bind; cl01081"
                     /db_xref="CDD:242292"
     gene            158334..159356
                     /gene="queA"
                     /locus_tag="COSY_0147"
                     /db_xref="GeneID:5172544"
     CDS             158334..159356
                     /gene="queA"
                     /locus_tag="COSY_0147"
                     /note="queuosine biosynthesis protein"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase"
                     /protein_id="YP_001219005.1"
                     /db_xref="GI:148244311"
                     /db_xref="GeneID:5172544"
                     /translation="MQLKDFDFDLPASLIAQHPIKNRTDSRLLIKRSSIIDIQFNQIG
                     DFFQSGDLLIMNNTKVIPARLFGTKETGGKVEIMIERILDENQVLAMIKASRAPKIGS
                     CIFLENDVNIIVYQKDNGFYTLIFETDSLFDLLNNIGHTPLPPYIKRTNNVQDLSRYQ
                     TVYAQKDGAVAAPTAGLHFDDSLLAQLKIQGIDHLFVTLHIGSGTFTPIRTDNIKNHV
                     MHSEIFEISQVTVDRINLTKANGGRIIAVGTTTVRVLESSLKNGKLIAQNGETDIFIY
                     PSYQFRIVDSLITNFHLPKSSLLMLVSAFIGRDKMLELYKHAIEQKYKFLSYGDAMFL
                     EKNNDL"
     misc_feature    158337..159338
                     /gene="queA"
                     /locus_tag="COSY_0147"
                     /note="Queuosine biosynthesis protein; Region:
                     Queuosine_synth; pfam02547"
                     /db_xref="CDD:217096"
     misc_feature    158340..159335
                     /gene="queA"
                     /locus_tag="COSY_0147"
                     /note="S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase; Region: queA; TIGR00113"
                     /db_xref="CDD:232830"
     gene            complement(159806..160576)
                     /locus_tag="COSY_0148"
                     /db_xref="GeneID:5172207"
     CDS             complement(159806..160576)
                     /locus_tag="COSY_0148"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219006.1"
                     /db_xref="GI:148244312"
                     /db_xref="GeneID:5172207"
                     /translation="MKKPIIVLGIGELGSVFSRAFLKNNYPVYPITRQTNINELANTI
                     NPELVLICTAEDDLQNALHSTPDKWKDRITMIQNELLPRDWQTHNFIDPTVISVWFEK
                     KKGIDPKVLISSPIYGKKAKILIDSLALINIPSHIINSEEELLFELVLKNLYILTTNI
                     VGLVIESDANINDLRNKHSSLMSNVSNDIIAIQTKLTGKTFDKKKLEQGIIKIFESDL
                     EHNCMGRFALTRLKRTLKLAKKFNLSVPALKKIANEHV"
     misc_feature    complement(<160391..>160558)
                     /locus_tag="COSY_0148"
                     /note="Medium chain reductase/dehydrogenase
                     (MDR)/zinc-dependent alcohol dehydrogenase-like family;
                     Region: MDR; cl16912"
                     /db_xref="CDD:247637"
     gene            complement(160573..161442)
                     /gene="sucD"
                     /locus_tag="COSY_0149"
                     /db_xref="GeneID:5172013"
     CDS             complement(160573..161442)
                     /gene="sucD"
                     /locus_tag="COSY_0149"
                     /EC_number="6.2.1.5"
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-CoA synthetase alpha subunit"
                     /protein_id="YP_001219007.1"
                     /db_xref="GI:148244313"
                     /db_xref="GeneID:5172013"
                     /translation="MSILIDKNTRVITQGFTGKQGTFHSKQSIIYGTQIVGGVTPNKG
                     GQRHLNLPVFNTTKEAINETLANASIIYVPPRFAYASILEAIETNIPVIACITEGIPV
                     QDMLKIKAILKKSDSTLIGPNCPGVITPDECKLGIMPGNIHKAGSVGVISRSGTLTYE
                     AVHQTTLVGLGQSTCIGIGGDPIQGMDFIDCLALFETDSQTKSIVMIGEIGGSTEEEA
                     AEYIQSNISKPVISYIAGLNVPQGKRMGHSGAVISAGTGKAIDKIKALRKVGVAIAPT
                     PTSIGETLLEILE"
     misc_feature    complement(160576..161442)
                     /gene="sucD"
                     /locus_tag="COSY_0149"
                     /note="succinyl-CoA synthetase subunit alpha; Validated;
                     Region: PRK05678"
                     /db_xref="CDD:180194"
     misc_feature    complement(161143..161433)
                     /gene="sucD"
                     /locus_tag="COSY_0149"
                     /note="CoA binding domain; Region: CoA_binding;
                     smart00881"
                     /db_xref="CDD:214881"
     misc_feature    complement(160630..160992)
                     /gene="sucD"
                     /locus_tag="COSY_0149"
                     /note="CoA-ligase; Region: Ligase_CoA; pfam00549"
                     /db_xref="CDD:215988"
     gene            complement(161439..162599)
                     /gene="sucC"
                     /locus_tag="COSY_0150"
                     /db_xref="GeneID:5172084"
     CDS             complement(161439..162599)
                     /gene="sucC"
                     /locus_tag="COSY_0150"
                     /EC_number="6.2.1.5"
                     /note="catalyzes the interconversion of succinyl-CoA and
                     succinate"
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-CoA synthetase subunit beta"
                     /protein_id="YP_001219008.1"
                     /db_xref="GI:148244314"
                     /db_xref="GeneID:5172084"
                     /translation="MHIHEYQAKTLFNHKHIQTPKGILIYSVDQASDACKTLGGSIWV
                     VKAQIHAGGRGKGGGIILCRSIEEVKNACSQLLNSQLITPQTYAKGLPVSQLLIEIGE
                     NITHEFYLGLLIDRQTKKITVLASTKGGMDIEKVARKTPNQIIKFGINPLGHLSVQDC
                     AFMAKKLDLHFKFTKQFNNILLGLYEIFTQKDVNLIEINPLVITKENKLLALDGKIDF
                     DDNALYRHKDIIALRDISQEDEKERLANIYHLNYISLNGTIGCMVNGAGLAMATMDLI
                     EHFGGSPANFLDVGGDTTADRVAKAFELIQTEENIKGILVNIFGGIVHCDLIAQGILQ
                     AIEKVRLTLPIVVRLEGTNATDGLKLLDKAKVDIHTESDLNKATIKIIKLAK"
     misc_feature    complement(161442..162599)
                     /gene="sucC"
                     /locus_tag="COSY_0150"
                     /note="succinyl-CoA synthetase subunit beta; Provisional;
                     Region: sucC; PRK00696"
                     /db_xref="CDD:234813"
     misc_feature    complement(161991..162596)
                     /gene="sucC"
                     /locus_tag="COSY_0150"
                     /note="ATP-grasp domain; Region: ATP-grasp_2; pfam08442"
                     /db_xref="CDD:219843"
     misc_feature    complement(<161538..161816)
                     /gene="sucC"
                     /locus_tag="COSY_0150"
                     /note="CoA-ligase; Region: Ligase_CoA; pfam00549"
                     /db_xref="CDD:215988"
     gene            163299..163862
                     /gene="efp"
                     /locus_tag="COSY_0151"
                     /db_xref="GeneID:5172062"
     CDS             163299..163862
                     /gene="efp"
                     /locus_tag="COSY_0151"
                     /note="Involved in peptide bond synthesis; alters the
                     affinity of the ribosome for aminoacyl-tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="YP_001219009.1"
                     /db_xref="GI:148244315"
                     /db_xref="GeneID:5172062"
                     /translation="MDKYSINQFKNGLKLMLDSNPCSILNNEIVKPGKGQAFNRVKFK
                     DLITGKTLIKTFKSGEFLEGADVMELDLQYLYNDGNAWNFMDPHSFEQYIIDGITVSS
                     VKGYLVEQDICIVTLWNDNPISITPPNHVILEVFDTDPGLKGDTIGASGKPATMNTGV
                     VLQVPLFVSIGDKVKVDTRINEYAGRA"
     misc_feature    163305..163859
                     /gene="efp"
                     /locus_tag="COSY_0151"
                     /note="elongation factor P; Validated; Region: PRK00529"
                     /db_xref="CDD:234788"
     misc_feature    163311..163484
                     /gene="efp"
                     /locus_tag="COSY_0151"
                     /note="Elongation factor P (EF-P) KOW-like domain; Region:
                     EFP_N; pfam08207"
                     /db_xref="CDD:203876"
     misc_feature    163500..163682
                     /gene="efp"
                     /locus_tag="COSY_0151"
                     /note="S1_EF-P_repeat_1: Translation elongation factor P
                     (EF-P), S1-like RNA-binding domain, repeat 1. EF-P
                     stimulates the peptidyltransferase activity in the
                     prokaryotic 70S ribosome. EF-P enhances the synthesis of
                     certain dipeptides with...; Region: S1_EF-P_repeat_1;
                     cd04470"
                     /db_xref="CDD:239916"
     misc_feature    order(163569..163571,163644..163646,163659..163664)
                     /gene="efp"
                     /locus_tag="COSY_0151"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:239916"
     misc_feature    163689..163856
                     /gene="efp"
                     /locus_tag="COSY_0151"
                     /note="S1_EF-P_repeat_2: Translation elongation factor P
                     (EF-P), S1-like RNA-binding domain, repeat 1. EF-P
                     stimulates the peptidyltransferase activity in the
                     prokaryotic 70S ribosome. EF-P enhances the synthesis of
                     certain dipeptides with...; Region: S1_EF-P_repeat_2;
                     cd05794"
                     /db_xref="CDD:240220"
     misc_feature    order(163776..163778,163827..163829,163842..163847)
                     /gene="efp"
                     /locus_tag="COSY_0151"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:240220"
     gene            163913..164797
                     /gene="genX"
                     /locus_tag="COSY_0152"
                     /db_xref="GeneID:5172457"
     CDS             163913..164797
                     /gene="genX"
                     /locus_tag="COSY_0152"
                     /EC_number="6.1.1.6"
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase, class II"
                     /protein_id="YP_001219010.1"
                     /db_xref="GI:148244316"
                     /db_xref="GeneID:5172457"
                     /translation="MFMIRNTLIKKQLIIQKIRQFFKEQEVLEVQTPILQNTSTSDVY
                     IDSISLTINTDIGIQSIQYLHTSPELEMKKLLAQGSGDIYQICQVFRNNEYGKQNFNE
                     FTLLEYYRLGFDIHQLMADMINLLKMLGIQDKVYQLSYAQVFNQYANIDILNTDIASL
                     KIIASKLGLSTDFVWIEDLQMLLFVHLVEPKLKNLPLCFIYDYPKSQSTLAKVKNQVA
                     KRFELYLNGVEVANGYDELQTKDEYQQVFICENNKRKQFSKLISQIDVSFLSKLSKPL
                     PQCTGVAIGINRLLTQIN"
     misc_feature    163982..164782
                     /gene="genX"
                     /locus_tag="COSY_0152"
                     /note="EF-P lysine aminoacylase GenX; Region: genX;
                     TIGR00462"
                     /db_xref="CDD:232984"
     misc_feature    163994..164779
                     /gene="genX"
                     /locus_tag="COSY_0152"
                     /note="Class II tRNA amino-acyl synthetase-like catalytic
                     core domain. Class II amino acyl-tRNA synthetases (aaRS)
                     share a common fold and generally attach an amino acid to
                     the 3&apos; OH of ribose of the appropriate tRNA.   PheRS
                     is an exception in that it...; Region:
                     class_II_aaRS-like_core; cl00268"
                     /db_xref="CDD:241739"
     misc_feature    order(163994..163999,164003..164005,164132..164137,
                     164180..164182,164186..164188)
                     /gene="genX"
                     /locus_tag="COSY_0152"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238391"
     misc_feature    163994..164005
                     /gene="genX"
                     /locus_tag="COSY_0152"
                     /note="motif 1; other site"
                     /db_xref="CDD:238391"
     misc_feature    order(164111..164113,164117..164119,164183..164185,
                     164219..164221,164225..164227,164231..164239,
                     164597..164602,164612..164614,164753..164758,
                     164762..164767,164774..164776)
                     /gene="genX"
                     /locus_tag="COSY_0152"
                     /note="active site"
                     /db_xref="CDD:238391"
     misc_feature    164180..164188
                     /gene="genX"
                     /locus_tag="COSY_0152"
                     /note="motif 2; other site"
                     /db_xref="CDD:238391"
     misc_feature    order(164765..164767,164774..164776)
                     /gene="genX"
                     /locus_tag="COSY_0152"
                     /note="motif 3; other site"
                     /db_xref="CDD:238391"
     gene            164822..166204
                     /locus_tag="COSY_0153"
                     /db_xref="GeneID:5172199"
     CDS             164822..166204
                     /locus_tag="COSY_0153"
                     /note="TPR repeat protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219011.1"
                     /db_xref="GI:148244317"
                     /db_xref="GeneID:5172199"
                     /translation="MIKFIYLILIFSLPIQALQILQSINDNKVIHQLDVPQLDTLLSA
                     EQLLTKLKKSAKRGDARSQFSLANMYNNGINVKKDNKLAFYWYLQVAEQDYASAQFNV
                     ANSYFYGLGVGKDLEQAFNWYKKAVKNGHVQAQYNLATLYLNGDGVEKNSKQAVYWYQ
                     KSAEQGYLEAYYHLALLQLIGNGINKDIKNALTVLLDLSAKGHQVSQYQLYLIYNKGE
                     IVVKNDILAKTYLLKAVKGGYAKAQYQLGKSFLDQGMDREEAVHYLELAANQKNVLAF
                     KLLEKLQSKLQKEVQNRQKKDTIHLATNIDQSIVAVASPMVGMPKQDIWPVKFNLNKQ
                     FNHVAANLIPNLSDIASSLSYNIKSHVNLEALLLNAKQGNPIAQYNLSMLYYKGEGVR
                     KDNRVAFILMQQSANQGITQSQNTLAKMYMNGSGIHIDYNKAYYWASVTTRKGSQQGK
                     RILLYLIANL"
     misc_feature    164912..>165562
                     /locus_tag="COSY_0153"
                     /note="FOG: TPR repeat, SEL1 subfamily [General function
                     prediction only]; Region: COG0790"
                     /db_xref="CDD:223861"
     misc_feature    164999..165106
                     /locus_tag="COSY_0153"
                     /note="Sel1-like repeats; Region: SEL1; smart00671"
                     /db_xref="CDD:214772"
     misc_feature    165107..165214
                     /locus_tag="COSY_0153"
                     /note="Sel1-like repeats; Region: SEL1; smart00671"
                     /db_xref="CDD:214772"
     misc_feature    165215..165322
                     /locus_tag="COSY_0153"
                     /note="Sel1-like repeats; Region: SEL1; smart00671"
                     /db_xref="CDD:214772"
     misc_feature    165800..>166189
                     /locus_tag="COSY_0153"
                     /note="FOG: TPR repeat, SEL1 subfamily [General function
                     prediction only]; Region: COG0790"
                     /db_xref="CDD:223861"
     misc_feature    165944..166048
                     /locus_tag="COSY_0153"
                     /note="Sel1-like repeats; Region: SEL1; smart00671"
                     /db_xref="CDD:214772"
     gene            166998..168209
                     /gene="argG"
                     /locus_tag="COSY_0154"
                     /db_xref="GeneID:5172652"
     CDS             166998..168209
                     /gene="argG"
                     /locus_tag="COSY_0154"
                     /EC_number="6.3.4.5"
                     /note="catalyzes the formation of
                     2-N(omega)-(L-arginino)succinate from L-citrulline and
                     L-aspartate in arginine biosynthesis, AMP-forming"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="YP_001219012.1"
                     /db_xref="GI:148244318"
                     /db_xref="GeneID:5172652"
                     /translation="MDKTSINKVVLAYSGGLDTSIIVKWLQDTYQCEVVTFTADIGQG
                     EEVEPARVKAEAAGVKEIYIEDLREEFARNFVFPMFRANAIYEGEYLLGTSIARPLIS
                     KRLVEIAKQVGADAISHGATGKGNDQVRFELNAYALNADIQVIAPWREWDLSSRESLM
                     DYAQKHGIEIDYKKQSKKSPYSMDANLLHISYEGNILEDPWTEPEEDMWRWTLSPENA
                     PDKVEYVEMTFKKGDIIAINGKVMSPASVMEDLNKRAGAHGIGRDDIVENRFVGMKSR
                     GCYETPSGTVMLKARRAMESLTLDRAAAHLKDELMPKYAEMVYNGFWFAPEREMLQAA
                     IDKTQETVSGVVRLKFYKGNVTVVGRQSKNSLFSEKIVTFENDDGIYNQRDAAGFIKL
                     NALRLCLNTIK"
     misc_feature    167019..168182
                     /gene="argG"
                     /locus_tag="COSY_0154"
                     /note="argininosuccinate synthase; Provisional; Region:
                     PRK13820"
                     /db_xref="CDD:237521"
     misc_feature    167022..168185
                     /gene="argG"
                     /locus_tag="COSY_0154"
                     /note="Argininosuccinate synthase. The Argininosuccinate
                     synthase is a urea cycle enzyme that catalyzes the
                     penultimate step in arginine biosynthesis: the
                     ATP-dependent ligation of citrulline to aspartate to form
                     argininosuccinate, AMP and pyrophosphate .  In...; Region:
                     Argininosuccinate_Synthase; cd01999"
                     /db_xref="CDD:238957"
     misc_feature    order(167031..167033,167052..167054,167106..167108,
                     167112..167114,167124..167126,167289..167291,
                     167355..167357,167388..167390,167541..167546)
                     /gene="argG"
                     /locus_tag="COSY_0154"
                     /note="ANP binding site [chemical binding]; other site"
                     /db_xref="CDD:238957"
     misc_feature    order(167265..167267,167277..167282,167373..167375,
                     167385..167387,167541..167549,167568..167570,
                     167574..167576,167796..167798,167832..167834,
                     167952..167954)
                     /gene="argG"
                     /locus_tag="COSY_0154"
                     /note="Substrate Binding Site II [chemical binding]; other
                     site"
                     /db_xref="CDD:238957"
     misc_feature    order(167358..167363,167370..167378)
                     /gene="argG"
                     /locus_tag="COSY_0154"
                     /note="Substrate Binding Site I [chemical binding]; other
                     site"
                     /db_xref="CDD:238957"
     gene            complement(168277..168350)
                     /locus_tag="COSY_t07"
                     /db_xref="GeneID:5329749"
     tRNA            complement(168277..168350)
                     /locus_tag="COSY_t07"
                     /product="tRNA-Cys"
                     /db_xref="GeneID:5329749"
     gene            complement(168402..168477)
                     /locus_tag="COSY_t08"
                     /db_xref="GeneID:5329758"
     tRNA            complement(168402..168477)
                     /locus_tag="COSY_t08"
                     /product="tRNA-Gly"
                     /db_xref="GeneID:5329758"
     gene            complement(168538..169116)
                     /gene="pgsA"
                     /locus_tag="COSY_0157"
                     /db_xref="GeneID:5172153"
     CDS             complement(168538..169116)
                     /gene="pgsA"
                     /locus_tag="COSY_0157"
                     /EC_number="2.7.8.5"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="YP_001219013.1"
                     /db_xref="GI:148244319"
                     /db_xref="GeneID:5172153"
                     /translation="MVTIPNILTLSRIFLIPVFVSLYYFQPTYSITPVFTWINFLLTS
                     TYALISATDYFDGYLARKLDMTSQLGAFLDPVADKLMVSTALILLVDFYPTDTHWYIS
                     VCALIIISREILISALREWMGTIGQRSNINVSWMGKMKTFVQIFAILFLLYQQSFFGL
                     PSFKIGVTLLLIATFLTLWSGFIYLKKGAQNF"
     misc_feature    complement(168562..169107)
                     /gene="pgsA"
                     /locus_tag="COSY_0157"
                     /note="CDP-alcohol phosphatidyltransferase; Region:
                     CDP-OH_P_transf; cl00453"
                     /db_xref="CDD:241872"
     gene            complement(169152..169228)
                     /locus_tag="COSY_t09"
                     /db_xref="GeneID:5329762"
     tRNA            complement(169152..169228)
                     /locus_tag="COSY_t09"
                     /product="tRNA-Arg"
                     /db_xref="GeneID:5329762"
     gene            complement(169282..170562)
                     /gene="murF"
                     /locus_tag="COSY_0159"
                     /db_xref="GeneID:5171839"
     CDS             complement(169282..170562)
                     /gene="murF"
                     /locus_tag="COSY_0159"
                     /EC_number="6.3.2.10"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-
                     diaminopimelate--D-alanyl-D-alanine ligase"
                     /protein_id="YP_001219014.1"
                     /db_xref="GI:148244320"
                     /db_xref="GeneID:5171839"
                     /translation="MLQTTTNTIAKVLKIDYSVNVKFKGVYTDTRKRMDGALFIALVG
                     DNFDAHDYIYQAQQMGAVAIIANKSVDSQLPILVVNDTQTALSTIASWHLQNIKPIVI
                     AITGSNGKTTTKNMLANILSLQAPTLKTQGNLNNHLGVPMTLLTLEKQHQYAVIEMGA
                     NHLGEISHLRKIVNPDIAIVTNTLDAHIGTFGGFDNLVKAKGEIYSKNSKNIINTQSI
                     FTGDVSFTPHGNTKVSGNNGDIFASNIVNNKFDLNIHQQKISITLNLIGIHNIDNALA
                     ASACVYPLGIDINLIKQGLEATKAEPGRLEIIHTKQFRIIDDTYNANPYSTIIALKTL
                     QNFSGEKIIVLGTMEELGNYSKMFHFKIGQLAKKSADTFYSYGKIALHHCSIHFEKKQ
                     PLANHILTNHTNATILIKGSRMAKLNKLVDLLKK"
     misc_feature    complement(170284..170499)
                     /gene="murF"
                     /locus_tag="COSY_0159"
                     /note="Mur ligase family, catalytic domain; Region:
                     Mur_ligase; pfam01225"
                     /db_xref="CDD:216373"
     misc_feature    complement(169291..170481)
                     /gene="murF"
                     /locus_tag="COSY_0159"
                     /note="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine
                     ligase; Region: murF; TIGR01143"
                     /db_xref="CDD:233291"
     misc_feature    complement(169750..170250)
                     /gene="murF"
                     /locus_tag="COSY_0159"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:219763"
     misc_feature    complement(<169450..169659)
                     /gene="murF"
                     /locus_tag="COSY_0159"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:217262"
     gene            complement(171068..172462)
                     /gene="murE"
                     /locus_tag="COSY_0160"
                     /db_xref="GeneID:5172023"
     CDS             complement(171068..172462)
                     /gene="murE"
                     /locus_tag="COSY_0160"
                     /EC_number="6.3.2.13"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-
                     diaminopimelate ligase"
                     /protein_id="YP_001219015.1"
                     /db_xref="GI:148244321"
                     /db_xref="GeneID:5172023"
                     /translation="MNISQLLINIIQTEVDIEIKGLCLNTQSAQPGDLFIALQGESTN
                     GTDYINQAIDKGCVAILVDSKEIECAIPSIRVNNLPIYLQTLANTFYNNATKIDVIGV
                     TGTNGKTSVTYLISQLLEKLGVKNGLIGTLGITHNKQLYFNTTPDILTLYRVLHHYYQ
                     QDIHYAVIEISSHALAQNRIAGLNIKQAVFTNLTQDHLDYHHTLDEYKTTKQRLFTLN
                     CVKSVILNQDDHHYKHFLKVSKGKKQTSYSLNDFNSIKIIQQGFLVQLDHYVFEIPFL
                     GEFNLLNILATLNSVEALGFKRNDIIPLIYQLSTPPGRMQQINHYHAWIDYAHTPNAL
                     ENAITTLQKHYPNFKIRIVFGCGGNRDRNKRSKMGRIASKLADSIILTNDNPRSENPQ
                     TIINDILNGIDDSFELDIIKDRQLAIETAMITLKKNECLIITGKGHETTQQLFNKIIY
                     LNDLQIAQNSIKDT"
     misc_feature    complement(171089..172462)
                     /gene="murE"
                     /locus_tag="COSY_0160"
                     /note="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase; Provisional; Region: murE;
                     PRK00139"
                     /db_xref="CDD:234660"
     misc_feature    complement(172190..172411)
                     /gene="murE"
                     /locus_tag="COSY_0160"
                     /note="Mur ligase family, catalytic domain; Region:
                     Mur_ligase; pfam01225"
                     /db_xref="CDD:216373"
     misc_feature    complement(171620..172156)
                     /gene="murE"
                     /locus_tag="COSY_0160"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:219763"
     misc_feature    complement(171278..171532)
                     /gene="murE"
                     /locus_tag="COSY_0160"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:217262"
     gene            172596..174485
                     /gene="soxB"
                     /locus_tag="COSY_0161"
                     /db_xref="GeneID:5172731"
     CDS             172596..174485
                     /gene="soxB"
                     /locus_tag="COSY_0161"
                     /note="sulfate thiol esterase"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur oxidation protein SoxB"
                     /protein_id="YP_001219016.1"
                     /db_xref="GI:148244322"
                     /db_xref="GeneID:5172731"
                     /translation="MALTRRDFIKVLGAGSAVGLISGCGNDTDKLSSQDNRYEVAKTG
                     NARILHITDTHGNLLPNYFREPNVNLGFGPTFGQLPHVVGNNLLKQIGVKAGSADAYA
                     FTYNNFEDLAAKYGKTGGFGQIKTVLDSLRESAGGVQNTLTLDGGDTWQGSGTSLWTR
                     GADMVEACNILGVDVMVGHWEFTYKEEETLKNINFFKGNFLGQNIRIVEDALMGDSYV
                     TMTERYDGNGLFNEEDALPFRSYVIKNVGGNRIAVIGQAFPRTSNANPKKYFFPDWSF
                     GLREDEMNELVTDIRKNKKPDAIIVISHNGMDVDIKMASRISGIDAIFGGHTHDGIPK
                     PVEVNNAGGVTVVTNAGCSGKYVGVMDLNIKDHKVMGYEYKMLPILTNFIKPDVSMMS
                     FINQMRTTKYDKNVVEARSDKMSNNLDRIGKTYDAILTEKLCTTEQTLYRRGNFMGTW
                     DQVLVNSLREEYNADFSMSAGVRWGTSVPAGHDVTMEDLMTNTSMTYGETYVNEMKGS
                     QLKEILEGIADNLFVQDPYLQSGGDMVRMGGMDYTIDPVASFGKRISNMKDDEGIAID
                     QNKSYRVSGWAQVDSVGNGRLMWDVAADYLRKQKHLNLTKINHPTIKGVNNNPGIENY
                     GGKLI"
     misc_feature    172608..174413
                     /gene="soxB"
                     /locus_tag="COSY_0161"
                     /note="bifunctional UDP-sugar
                     hydrolase/5&apos;-nucleotidase periplasmic precursor;
                     Reviewed; Region: ushA; PRK09558"
                     /db_xref="CDD:236566"
     misc_feature    172731..173732
                     /gene="soxB"
                     /locus_tag="COSY_0161"
                     /note="Thermus thermophilus SoxB and related proteins,
                     N-terminal metallophosphatase domain; Region: MPP_SoxB_N;
                     cd07411"
                     /db_xref="CDD:163654"
     misc_feature    order(172752..172754,172758..172760,173037..173039,
                     173130..173135,173505..173507,173574..173576,
                     173580..173582)
                     /gene="soxB"
                     /locus_tag="COSY_0161"
                     /note="active site"
                     /db_xref="CDD:163654"
     misc_feature    order(172752..172754,172758..172760,173037..173039,
                     173130..173132,173505..173507,173574..173576,
                     173580..173582)
                     /gene="soxB"
                     /locus_tag="COSY_0161"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163654"
     misc_feature    173949..174314
                     /gene="soxB"
                     /locus_tag="COSY_0161"
                     /note="5&apos;-nucleotidase, C-terminal domain; Region:
                     5_nucleotid_C; pfam02872"
                     /db_xref="CDD:217260"
     gene            complement(175535..176515)
                     /locus_tag="COSY_0163"
                     /db_xref="GeneID:5171934"
     CDS             complement(175535..176515)
                     /locus_tag="COSY_0163"
                     /EC_number="5.3.1.13"
                     /note="arabinose-5-phosphate isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="polysialic acid capsule expression protein"
                     /protein_id="YP_001219017.1"
                     /db_xref="GI:148244323"
                     /db_xref="GeneID:5171934"
                     /translation="MYLLTMSNSLLQSAKNVILTEAKAVTMLADSLDQNFIDACQLIQ
                     NCTGKVVLIGMGKSGHIASKIAATLASTGTPAFAVHPGEAGHGDLGMITQEDVVITIS
                     YSGESDEIMTLIPIIKHLGVFIIGMTGNVNSSISKISDVHLDVNVEKEACPHNLAPTS
                     STTVALVMGDALAISLLTNKGFSVDDFARSHPSGALGRRLLTFVSTIMKTGNDIPMVS
                     ADIKLLNALLVMSQKTLGMVLITDNNTLKGIFTDGDLRRVLETHPNIQTLTIGEVMTH
                     NCQSISADKPAIAAVQMMDKFNLNSLPVVDDNNQILGAINTHTLMQAKII"
     misc_feature    complement(175538..176482)
                     /locus_tag="COSY_0163"
                     /note="D-arabinose 5-phosphate isomerase; Provisional;
                     Region: PRK10892"
                     /db_xref="CDD:182814"
     misc_feature    complement(175991..176374)
                     /locus_tag="COSY_0163"
                     /note="KpsF-like protein. KpsF is an arabinose-5-phosphate
                     isomerase which contains SIS (Sugar ISomerase) domains.
                     SIS domains are found in many phosphosugar isomerases and
                     phosphosugar binding proteins. KpsF catalyzes the
                     reversible reaction of ribulose...; Region: SIS_Kpsf;
                     cd05014"
                     /db_xref="CDD:240145"
     misc_feature    complement(order(176210..176212,176342..176344))
                     /locus_tag="COSY_0163"
                     /note="putative active site [active]"
                     /db_xref="CDD:240145"
     misc_feature    complement(175547..175885)
                     /locus_tag="COSY_0163"
                     /note="This cd contains two tandem repeats of the
                     cystathionine beta-synthase (CBS pair) domains associated
                     with KpsF/GutQ domains in the API [A5P (D-arabinose
                     5-phosphate) isomerase] protein.  These APIs catalyze the
                     conversion of the pentose pathway...; Region:
                     CBS_pair_KpsF_GutQ_assoc; cd04604"
                     /db_xref="CDD:239977"
     gene            176960..177334
                     /gene="rpsL"
                     /locus_tag="COSY_0164"
                     /db_xref="GeneID:5171859"
     CDS             176960..177334
                     /gene="rpsL"
                     /locus_tag="COSY_0164"
                     /note="interacts with and stabilizes bases of the 16S rRNA
                     that are involved in tRNA selection in the A site and with
                     the mRNA backbone; located at the interface of the 30S and
                     50S subunits, it traverses the body of the 30S subunit
                     contacting proteins on the other side; mutations in the
                     S12 gene confer streptomycin resistance"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="YP_001219018.1"
                     /db_xref="GI:148244324"
                     /db_xref="GeneID:5171859"
                     /translation="MSTINQLVRNPRKKKVIKSGVPALDSCPQKRGVCTRVYTTTPKK
                     PNSALRKVARVRLTNANEVTTYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DTTGVDSRMQGRSKYGTKKPKK"
     misc_feature    176966..177289
                     /gene="rpsL"
                     /locus_tag="COSY_0164"
                     /note="S12-like family, 30S ribosomal protein S12
                     subfamily; S12 is located at the interface of the large
                     and small ribosomal subunits of prokaryotes, chloroplasts
                     and mitochondria, where it plays an important role in both
                     tRNA and ribosomal subunit...; Region: Ribosomal_S12;
                     cd03368"
                     /db_xref="CDD:239466"
     misc_feature    order(176969..176974,176978..176983,176990..176995)
                     /gene="rpsL"
                     /locus_tag="COSY_0164"
                     /note="S17 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239466"
     misc_feature    176969..176971
                     /gene="rpsL"
                     /locus_tag="COSY_0164"
                     /note="S8 interaction site; other site"
                     /db_xref="CDD:239466"
     misc_feature    order(176993..177001,177035..177037,177041..177046,
                     177050..177052,177095..177100,177104..177112,
                     177131..177133,177155..177157,177164..177169,
                     177206..177211,177221..177226,177287..177289)
                     /gene="rpsL"
                     /locus_tag="COSY_0164"
                     /note="16S rRNA interaction site [nucleotide binding];
                     other site"
                     /db_xref="CDD:239466"
     misc_feature    order(177086..177091,177221..177223)
                     /gene="rpsL"
                     /locus_tag="COSY_0164"
                     /note="streptomycin interaction site [chemical binding];
                     other site"
                     /db_xref="CDD:239466"
     misc_feature    177089..177094
                     /gene="rpsL"
                     /locus_tag="COSY_0164"
                     /note="23S rRNA interaction site [nucleotide binding];
                     other site"
                     /db_xref="CDD:239466"
     misc_feature    order(177092..177109,177167..177193)
                     /gene="rpsL"
                     /locus_tag="COSY_0164"
                     /note="aminoacyl-tRNA interaction site (A-site)
                     [nucleotide binding]; other site"
                     /db_xref="CDD:239466"
     gene            177367..177834
                     /gene="rpsG"
                     /locus_tag="COSY_0165"
                     /db_xref="GeneID:5172410"
     CDS             177367..177834
                     /gene="rpsG"
                     /locus_tag="COSY_0165"
                     /note="binds directly to 16S rRNA where it nucleates
                     assembly of the head domain of the 30S subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="YP_001219019.1"
                     /db_xref="GI:148244325"
                     /db_xref="GeneID:5172410"
                     /translation="MRRRSAPKREILPDPKFGDLVLAKFINILMFDGKKSVAEKIVYE
                     ALDTIKAKGNAQPIEVFKQALDKIGPQVEIKSRRVGGSTYQVPIEVRTERKSALAMRW
                     IIEASRKRGAKSMKLRLAGEILDAIQNRGNAFKKKEDSHRMAEANKAFAHFRW"
     misc_feature    177367..177831
                     /gene="rpsG"
                     /locus_tag="COSY_0165"
                     /note="30S ribosomal protein S7; Validated; Region:
                     PRK05302"
                     /db_xref="CDD:235398"
     gene            177859..179961
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /db_xref="GeneID:5172475"
     CDS             177859..179961
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="EF-G; promotes GTP-dependent translocation of the
                     ribosome during translation; many organisms have multiple
                     copies of this gene"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="YP_001219020.1"
                     /db_xref="GI:148244326"
                     /db_xref="GeneID:5172475"
                     /translation="MARTTPLDRYRNVGIMAHIDAGKTTTTERILLYTGRTHRIGEVH
                     DGSATMDWMEQEQERGITITSAATTCFWKGMDGQFEDHRVNIIDTPGHVDFTIEVERS
                     LKVLDSACAVFCAVGGVEPQSETVWRQANKYNVPRIGFVNKMDRSGADFLRVCKQIKT
                     RLGGNPVPMQIAIGAEESFEGVIDLISMKAIFWNEVDQGATYETRDIPIELQGLAKEQ
                     YEFMVESAAEANDELMEKYLEESKLSNHDIKKGIRLRAIKSEIIPMFCGSAFKNKGVQ
                     AVLDAMIMYMPSPLDVDAITGISDDKDETVVPRKADDNEPFAALAFKIATDPFVGNLT
                     FFRVYSGVLEAGDFVYNSSKGKKERIGRMVQMHSNERDEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDMKEKIILERMEFPEPVIALAVEPKTKADQEKMGIALGKLAAEDPSFRVSTD
                     EESGQTIIAGMGELHLDIIVDRMVREFDVECNVGAPQVSYREAITTMVEHQHKFVKQS
                     GGRGQYGHVYLRIEPQEPGTGYEFVDEIKGGVIPKEYMPAVNKGVQEQMENGVLAGFP
                     LVDIKVTVYDGSYHDVDSNEIAFKIAASKCLSEGVKMANPQLLEPMMAVEVLTPEDYM
                     GDVMGDINRRRGIVSAMEDMPAGKQVKAEVPLAEMFGYSNDLRSITQGRANYSMEFAK
                     YTAAPKNVADEIIEKLNK"
     misc_feature    177859..179958
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="elongation factor G; Reviewed; Region: PRK00007"
                     /db_xref="CDD:234569"
     misc_feature    177892..178725
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="Elongation factor G (EF-G) family involved in both
                     the elongation and ribosome recycling phases of protein
                     synthesis; Region: EF-G; cd01886"
                     /db_xref="CDD:206673"
     misc_feature    177907..177930
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="G1 box; other site"
                     /db_xref="CDD:206673"
     misc_feature    order(177910..177912,177916..177918,177928..177933,
                     177940..177942,177949..177954,178054..178059,
                     178132..178137,178204..178209,178315..178317,
                     178327..178329)
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="putative GEF interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:206673"
     misc_feature    order(177916..177918,177922..177933,178282..178287,
                     178291..178293,178660..178668)
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206673"
     misc_feature    177997..178056
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206673"
     misc_feature    178042..178044
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="G2 box; other site"
                     /db_xref="CDD:206673"
     misc_feature    178120..178131
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="G3 box; other site"
                     /db_xref="CDD:206673"
     misc_feature    178126..178182
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206673"
     misc_feature    178282..178293
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="G4 box; other site"
                     /db_xref="CDD:206673"
     misc_feature    178660..178668
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="G5 box; other site"
                     /db_xref="CDD:206673"
     misc_feature    178807..179055
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="EFG_mtEFG_II: this subfamily represents the domain
                     II of elongation factor G (EF-G) in bacteria and, the
                     C-terminus of mitochondrial Elongation factor G1 (mtEFG1)
                     and G2 (mtEFG2)_like proteins found in eukaryotes. During
                     the process of peptide synthesis...; Region: EFG_mtEFG_II;
                     cd04088"
                     /db_xref="CDD:239755"
     misc_feature    179326..179673
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="EFG_mtEFG1_IV: domains similar to domain IV of the
                     bacterial translational elongation factor (EF) EF-G.
                     Included in this group is a domain of mitochondrial
                     Elongation factor G1 (mtEFG1) proteins homologous to
                     domain IV of EF-G. Eukaryotic cells harbor 2...; Region:
                     EFG_mtEFG1_IV; cd01434"
                     /db_xref="CDD:238715"
     misc_feature    179686..179919
                     /gene="fusA"
                     /locus_tag="COSY_0166"
                     /note="EFG_mtEFG_C: domains similar to the C-terminal
                     domain of the bacterial translational elongation factor
                     (EF) EF-G.  Included in this group is the C-terminus of
                     mitochondrial Elongation factor G1 (mtEFG1) and G2
                     (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region:
                     EFG_mtEFG_C; cd03713"
                     /db_xref="CDD:239683"
     gene            179972..181162
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /db_xref="GeneID:5172233"
     CDS             179972..181162
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /EC_number="3.6.5.3"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="YP_001219021.1"
                     /db_xref="GI:148244327"
                     /db_xref="GeneID:5172233"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITKVMAEVRGGEF
                     KDYADIDNAPEERERGITISTAHVEYESEIRHYAHVDCPGHADYIKNMITGAAQMDGA
                     IIVIAATDGPMAQTREHILLSKQVGVPYIVVYMNKADMVDDEELVELVEMEIRELLDE
                     YDFPGDDTPVIFGSALKALEGDISDIGVPSILKLVDALDSYIPTPKRDTDKSFIMPIE
                     DVFSISGRGTVVTGRIEAGVVNIGDELEIVGIKDTKTTTCTGVEMFRKLLSSGEAGDN
                     VGVLLRGTKREEVERGQVLSKPGSIKPHAKFEAEIYILSKDEGGRHTPFFNNYRPQFY
                     FRTTDVTGACQLPDGIEMVMPGDNVKMRVELLSPIAMEDGLRFAIREGGRTVGAGVVS
                     KVTD"
     misc_feature    179972..181159
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="elongation factor Tu; Reviewed; Region: PRK00049"
                     /db_xref="CDD:234596"
     misc_feature    180002..180586
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="Elongation Factor Tu (EF-Tu) GTP-binding proteins;
                     Region: EF_Tu; cd01884"
                     /db_xref="CDD:206671"
     misc_feature    180026..180049
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="G1 box; other site"
                     /db_xref="CDD:206671"
     misc_feature    order(180029..180031,180035..180037,180047..180052,
                     180059..180061,180068..180073,180083..180085,
                     180167..180172,180224..180229,180296..180301,
                     180305..180316,180323..180325,180416..180418,
                     180428..180430,180506..180511)
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="GEF interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:206671"
     misc_feature    order(180035..180052,180110..180112,180377..180382,
                     180386..180388,180491..180499)
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206671"
     misc_feature    180137..180169
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206671"
     misc_feature    180155..180157
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="G2 box; other site"
                     /db_xref="CDD:206671"
     misc_feature    180212..180223
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="G3 box; other site"
                     /db_xref="CDD:206671"
     misc_feature    180218..180274
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206671"
     misc_feature    180377..180388
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="G4 box; other site"
                     /db_xref="CDD:206671"
     misc_feature    180491..180499
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="G5 box; other site"
                     /db_xref="CDD:206671"
     misc_feature    180608..180868
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="EFTU_II: Elongation factor Tu domain II. Elongation
                     factors Tu (EF-Tu) are three-domain GTPases with an
                     essential function in the elongation phase of mRNA
                     translation. The GTPase center of EF-Tu is in the
                     N-terminal domain (domain I), also known as the...;
                     Region: EFTU_II; cd03697"
                     /db_xref="CDD:239668"
     misc_feature    180875..181144
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="Domain III of elongation factor (EF) Tu. Ef-Tu
                     consists of three structural domains, designated I, II and
                     III. Domain III adopts a beta barrel structure. Domain III
                     is involved in binding to both charged tRNA and binding to
                     elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707"
                     /db_xref="CDD:239678"
     misc_feature    order(180911..180913,180917..180925,180977..180979,
                     181097..181105,181133..181135)
                     /gene="tufA"
                     /locus_tag="COSY_0167"
                     /gene_synonym="tuf"
                     /note="Antibiotic Binding Site [chemical binding]; other
                     site"
                     /db_xref="CDD:239678"
     gene            181250..181561
                     /gene="rpsJ"
                     /locus_tag="COSY_0168"
                     /db_xref="GeneID:5171922"
     CDS             181250..181561
                     /gene="rpsJ"
                     /locus_tag="COSY_0168"
                     /note="NusE; involved in assembly of the 30S subunit; in
                     the ribosome, this protein is involved in the binding of
                     tRNA; in Escherichia coli this protein was also found to
                     be involved in transcription antitermination; NusB/S10
                     heterodimers bind boxA sequences in the leader RNA of rrn
                     operons which is required for antitermination; binding of
                     NusB/S10 to boxA nucleates assembly of the antitermination
                     complex"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="YP_001219022.1"
                     /db_xref="GI:148244328"
                     /db_xref="GeneID:5171922"
                     /translation="MSNQNIRIKLKAFDHRLIDKSAVEIVETAKRTGASVRGPIPLPT
                     KKERFTVLTSPHVNKKARDQYELRTYVRLMDVISPTDKTVDALMKLDLAAGVDVAIKL
                     N"
     misc_feature    181250..181555
                     /gene="rpsJ"
                     /locus_tag="COSY_0168"
                     /note="30S ribosomal protein S10; Reviewed; Region: rpsJ;
                     PRK00596"
                     /db_xref="CDD:179076"
     gene            181590..182315
                     /gene="rplC"
                     /locus_tag="COSY_0169"
                     /db_xref="GeneID:5171967"
     CDS             181590..182315
                     /gene="rplC"
                     /locus_tag="COSY_0169"
                     /note="binds directly near the 3' end of the 23S rRNA,
                     where it nucleates assembly of the 50S subunit; essential
                     for peptidyltransferase activity; mutations in this gene
                     confer resistance to tiamulin"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="YP_001219023.1"
                     /db_xref="GI:148244329"
                     /db_xref="GeneID:5171967"
                     /translation="MAIDLVGQKIGMTRLISDDGSIMPVSVIKIEPNRIVQTRTIDID
                     GYRAIQVTTGKKVNKKGEAKVRRISAAIKGHYAKASQEIGLGLWEFKLEDNEITNATS
                     IDISLFGAGHYVDVIGKSKGKGFQGGVKLHNFQMQDATHGNSISHRAIGSTGQCQEPG
                     RVFKGKKMAGHMGNKQVTQECLKVVKVDIEKSVILVKGSIPGAIKGFVKVSLSPKKDN
                     SNKEVSKNIKNQVTNEVDQTKQM"
     misc_feature    181590..182237
                     /gene="rplC"
                     /locus_tag="COSY_0169"
                     /note="50S ribosomal protein L3; Validated; Region: rplC;
                     PRK00001"
                     /db_xref="CDD:234564"
     gene            182329..182943
                     /gene="rplD"
                     /locus_tag="COSY_0170"
                     /db_xref="GeneID:5172658"
     CDS             182329..182943
                     /gene="rplD"
                     /locus_tag="COSY_0170"
                     /note="L4 is important during the early stages of 50S
                     assembly; it initially binds near the 5' end of the 23S
                     rRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="YP_001219024.1"
                     /db_xref="GI:148244330"
                     /db_xref="GeneID:5172658"
                     /translation="MELKVLNISLNSLNTVEVDDTIFARDFNQALVHQVTTAYMSGSR
                     QGSKAQKNRSAVSGGGKRPWAQKGTGRARAGTTRGPIWRSGGVTFATQPRSYAQKVNK
                     KMYKGAISIIFSELVRSERLKVVKEFDIKEVKTKNMIALLKVLNVKDALLMTDELDEN
                     LYLSSRNLYHVGVCDTQSIDPVSLIGYDNVVVTELALKKIEVML"
     misc_feature    182329..182940
                     /gene="rplD"
                     /locus_tag="COSY_0170"
                     /note="50S ribosomal protein L4; Provisional; Region:
                     rplD; PRK05319"
                     /db_xref="CDD:235404"
     gene            182940..183230
                     /gene="rplW"
                     /locus_tag="COSY_0171"
                     /db_xref="GeneID:5172661"
     CDS             182940..183230
                     /gene="rplW"
                     /locus_tag="COSY_0171"
                     /note="binds third domain of 23S rRNA and protein L29;
                     part of exit tunnel"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="YP_001219025.1"
                     /db_xref="GI:148244331"
                     /db_xref="GeneID:5172661"
                     /translation="MNQEKVLKTLLMPIVSEKMTMLSANNQYAFKVRMDSSKREIKAA
                     VEILLGVNVENVTTLIVKGKKKIFKGRTGSRPNWKKAMVKVSAGQIIDVNRT"
     misc_feature    182958..183218
                     /gene="rplW"
                     /locus_tag="COSY_0171"
                     /note="50S ribosomal protein L23; Reviewed; Region: rplW;
                     PRK05738"
                     /db_xref="CDD:235586"
     gene            183241..184071
                     /gene="rplB"
                     /locus_tag="COSY_0172"
                     /db_xref="GeneID:5172386"
     CDS             183241..184071
                     /gene="rplB"
                     /locus_tag="COSY_0172"
                     /note="one of the primary rRNA-binding proteins; required
                     for association of the 30S and 50S subunits to form the
                     70S ribosome, for tRNA binding and peptide bond formation"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="YP_001219026.1"
                     /db_xref="GI:148244332"
                     /db_xref="GeneID:5172386"
                     /translation="MAQVIKRKPTSPGRRFVVSIVDKELHKGTSYGPLTQNKNRINGR
                     NNAGRITMRHKGGGHKRRYRIIDFKRNKDDITARVERLEYDPNRSANIALILYADGKR
                     HYIIAPRGLSVGDMIVSGNSVAIQVGNVMPLSNIPLGSIVHCIELRPMKGAQIARSAG
                     TSAQLIAKRGTYVTLRLRSGEVRKVLTDCRATIGEVSRSEHSLRKLGKAGATRWHGVR
                     PTVRGVVMNSVDHPHGGGEGKTSGGRHPVSPWGTPTKGYKTRSNKRTDKLILRHRNKG
                     "
     misc_feature    183241..184068
                     /gene="rplB"
                     /locus_tag="COSY_0172"
                     /note="50S ribosomal protein L2; Validated; Region: rplB;
                     PRK09374"
                     /db_xref="CDD:236488"
     misc_feature    <183427..183597
                     /gene="rplB"
                     /locus_tag="COSY_0172"
                     /note="Ribosomal Proteins L2, RNA binding domain; Region:
                     Ribosomal_L2; pfam00181"
                     /db_xref="CDD:109247"
     misc_feature    183613..183999
                     /gene="rplB"
                     /locus_tag="COSY_0172"
                     /note="Ribosomal Proteins L2, C-terminal domain; Region:
                     Ribosomal_L2_C; pfam03947"
                     /db_xref="CDD:202823"
     gene            184076..184345
                     /gene="rpsS"
                     /locus_tag="COSY_0173"
                     /db_xref="GeneID:5172657"
     CDS             184076..184345
                     /gene="rpsS"
                     /locus_tag="COSY_0173"
                     /note="protein S19 forms a complex with S13 that binds
                     strongly to the 16S ribosomal RNA"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="YP_001219027.1"
                     /db_xref="GI:148244333"
                     /db_xref="GeneID:5172657"
                     /translation="MARSLRKGPFVDEHLIKKVLAAQGNNDRKPIKTWSRRSVVVPEM
                     IGLTIAVHNGRVHVPVSINENMVGHKLGEFAITRTFKGHFGDRKA"
     misc_feature    184076..184342
                     /gene="rpsS"
                     /locus_tag="COSY_0173"
                     /note="30S ribosomal protein S19; Reviewed; Region: rpsS;
                     PRK00357"
                     /db_xref="CDD:178985"
     gene            184366..184698
                     /gene="rplV"
                     /locus_tag="COSY_0174"
                     /db_xref="GeneID:5172421"
     CDS             184366..184698
                     /gene="rplV"
                     /locus_tag="COSY_0174"
                     /note="binds specifically to 23S rRNA during the early
                     stages of 50S assembly; makes contact with all 6 domains
                     of the 23S rRNA in the assembled 50S subunit and ribosome;
                     mutations in this gene result in erythromycin resistance;
                     located near peptidyl-transferase center"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="YP_001219028.1"
                     /db_xref="GI:148244334"
                     /db_xref="GeneID:5172421"
                     /translation="MKEVKAVHKYAKTSAFKARLVADQIRLKSVEEALNILSFSNKKA
                     AVLVKKVLNSVISNAEHNDGLDIDELFVTSIYIDEGSTMKRIRPRAKGRANRILKRTS
                     HITVGIGK"
     misc_feature    184375..184683
                     /gene="rplV"
                     /locus_tag="COSY_0174"
                     /note="Ribosomal protein L22/L17e.  L22 (L17 in
                     eukaryotes) is a core protein of the large ribosomal
                     subunit.  It is the only ribosomal protein that interacts
                     with all six domains of 23S rRNA, and is one of the
                     proteins important for directing the proper...; Region:
                     Ribosomal_L22; cd00336"
                     /db_xref="CDD:238205"
     misc_feature    order(184375..184380,184444..184452,184456..184461,
                     184465..184470,184531..184548,184573..184590)
                     /gene="rplV"
                     /locus_tag="COSY_0174"
                     /note="putative translocon binding site; other site"
                     /db_xref="CDD:238205"
     misc_feature    order(184384..184386,184390..184392,184399..184401,
                     184405..184413,184420..184422,184432..184434,
                     184441..184443,184525..184527,184537..184539,
                     184546..184548,184585..184587,184591..184599,
                     184603..184605,184612..184614,184648..184665)
                     /gene="rplV"
                     /locus_tag="COSY_0174"
                     /note="protein-rRNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238205"
     gene            184706..185398
                     /gene="rpsC"
                     /locus_tag="COSY_0175"
                     /db_xref="GeneID:5172079"
     CDS             184706..185398
                     /gene="rpsC"
                     /locus_tag="COSY_0175"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="YP_001219029.1"
                     /db_xref="GI:148244335"
                     /db_xref="GeneID:5172079"
                     /translation="MGQKVNPKGIRLGIIKDWDSKWYASSKDYSKYLLSDIKVRNYLF
                     KKLINASVSRVQIGRLVNNAKVTIYTARPGIVIGKKGADIEQLKLIVSKMMGIPVHIN
                     IEEIKKPELDARLVAENIAQQLEKRVMYRRAVKRVLGNATRLGAQGIKVMVSGRLNGA
                     EIARSEWYREGRVPLHTFRADVDYSSYGAKTQYGVIGIKVWIFKGEILDHKKGTLDEV
                     AHRGAINQIAKK"
     misc_feature    184706..185374
                     /gene="rpsC"
                     /locus_tag="COSY_0175"
                     /note="30S ribosomal protein S3; Reviewed; Region: rpsC;
                     PRK00310"
                     /db_xref="CDD:234722"
     misc_feature    184709..185032
                     /gene="rpsC"
                     /locus_tag="COSY_0175"
                     /note="K homology RNA-binding (KH) domain of the
                     prokaryotic 30S small ribosomal subunit protein S3. S3  is
                     part of the head region of the 30S ribosomal subunit and
                     is believed to interact with mRNA as it threads its way
                     from the latch into the channel.  The KH...; Region:
                     30S_S3_KH; cd02412"
                     /db_xref="CDD:239095"
     misc_feature    184937..184948
                     /gene="rpsC"
                     /locus_tag="COSY_0175"
                     /note="G-X-X-G motif; other site"
                     /db_xref="CDD:239095"
     misc_feature    185060..185311
                     /gene="rpsC"
                     /locus_tag="COSY_0175"
                     /note="Ribosomal protein S3, C-terminal domain; Region:
                     Ribosomal_S3_C; pfam00189"
                     /db_xref="CDD:215779"
     gene            185415..185825
                     /gene="rplP"
                     /locus_tag="COSY_0176"
                     /db_xref="GeneID:5172370"
     CDS             185415..185825
                     /gene="rplP"
                     /locus_tag="COSY_0176"
                     /note="located in the peptidyl transferase center and may
                     be involved in peptidyl transferase activity; similar to
                     archaeal L10e"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="YP_001219030.1"
                     /db_xref="GI:148244336"
                     /db_xref="GeneID:5172370"
                     /translation="MLQPKRTKFRKMMKGRNRGLATGHKVSFGEIGLQAVGRCRLSAR
                     QIESARRAMTRHVKRQGKIWIRVFPDKPVTKKPLEVRMGKGKGSVEYWVAKIKPGQML
                     FEMQGVEETVAIEAFALASGKLPVKTTIIKRTVM"
     misc_feature    185478..185807
                     /gene="rplP"
                     /locus_tag="COSY_0176"
                     /note="Ribosomal_L16_L10e: L16 is an essential protein in
                     the large ribosomal subunit of bacteria, mitochondria, and
                     chloroplasts. Large subunits that lack L16 are defective
                     in peptidyl transferase activity, peptidyl-tRNA hydrolysis
                     activity, association with...; Region: Ribosomal_L16_L10e;
                     cd01433"
                     /db_xref="CDD:238714"
     misc_feature    order(185478..185480,185484..185489,185496..185498,
                     185544..185549,185556..185558,185565..185567,
                     185577..185579,185586..185588,185604..185612,
                     185616..185618,185622..185624,185634..185639,
                     185658..185672,185712..185714,185766..185771,
                     185778..185783)
                     /gene="rplP"
                     /locus_tag="COSY_0176"
                     /note="23S rRNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238714"
     misc_feature    185523..185528
                     /gene="rplP"
                     /locus_tag="COSY_0176"
                     /note="5S rRNA interface [nucleotide binding]; other site"
                     /db_xref="CDD:238714"
     misc_feature    order(185559..185567,185574..185579)
                     /gene="rplP"
                     /locus_tag="COSY_0176"
                     /note="putative antibiotic binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238714"
     misc_feature    order(185586..185588,185595..185600,185604..185606,
                     185730..185732)
                     /gene="rplP"
                     /locus_tag="COSY_0176"
                     /note="L25 interface [polypeptide binding]; other site"
                     /db_xref="CDD:238714"
     misc_feature    order(185652..185657,185664..185669)
                     /gene="rplP"
                     /locus_tag="COSY_0176"
                     /note="L27 interface [polypeptide binding]; other site"
                     /db_xref="CDD:238714"
     gene            185825..186013
                     /gene="rpmC"
                     /locus_tag="COSY_0177"
                     /db_xref="GeneID:5172415"
     CDS             185825..186013
                     /gene="rpmC"
                     /locus_tag="COSY_0177"
                     /note="one of the stabilizing components for the large
                     ribosomal subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="YP_001219031.1"
                     /db_xref="GI:148244337"
                     /db_xref="GeneID:5172415"
                     /translation="MDVKELRNQSVSALNEMLIKLLKEHFEFRMQHKSSQLDNFSKLG
                     KTKKSIAQIKTIIRQKQA"
     misc_feature    185834..186004
                     /gene="rpmC"
                     /locus_tag="COSY_0177"
                     /note="Ribosomal L29 protein/HIP.  L29 is a protein of the
                     large ribosomal Subunit. A homolog, called heparin/heparan
                     sulfate interacting protein (HIP), has also been
                     identified in mammals.  L29 is located on the surface of
                     the large ribosomal subunit, where it...; Region:
                     Ribosomal_L29_HIP; cd00427"
                     /db_xref="CDD:238243"
     misc_feature    order(185834..185836,185843..185845,185945..185947,
                     185975..185980,185984..185989,185999..186001)
                     /gene="rpmC"
                     /locus_tag="COSY_0177"
                     /note="23S rRNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238243"
     misc_feature    order(185834..185842,185846..185848,185858..185863,
                     185867..185872,185879..185884,185891..185896,
                     185903..185905,185912..185917,185939..185941,
                     185948..185950,185960..185962,185969..185974,
                     185981..185986,185993..185995)
                     /gene="rpmC"
                     /locus_tag="COSY_0177"
                     /note="putative translocon interaction site; other site"
                     /db_xref="CDD:238243"
     misc_feature    order(185882..185884,185894..185896,185903..185905,
                     185915..185917,185960..185962)
                     /gene="rpmC"
                     /locus_tag="COSY_0177"
                     /note="signal recognition particle (SRP54) interaction
                     site; other site"
                     /db_xref="CDD:238243"
     misc_feature    order(185900..185902,185909..185914)
                     /gene="rpmC"
                     /locus_tag="COSY_0177"
                     /note="L23 interface [polypeptide binding]; other site"
                     /db_xref="CDD:238243"
     misc_feature    185921..185926
                     /gene="rpmC"
                     /locus_tag="COSY_0177"
                     /note="trigger factor interaction site; other site"
                     /db_xref="CDD:238243"
     gene            186010..186276
                     /gene="rpsQ"
                     /locus_tag="COSY_0178"
                     /db_xref="GeneID:5172536"
     CDS             186010..186276
                     /gene="rpsQ"
                     /locus_tag="COSY_0178"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="YP_001219032.1"
                     /db_xref="GI:148244338"
                     /db_xref="GeneID:5172536"
                     /translation="MNEKKVECVLTGTVVSSNRDKTITVLIERKVRHPIYKKYIKRST
                     KVHAHDDKNECICGDLVRVVEAKPFSKTKHWSLLEVVERLVSVD"
     misc_feature    186034..186234
                     /gene="rpsQ"
                     /locus_tag="COSY_0178"
                     /note="30S ribosomal protein S17; Reviewed; Region: rpsQ;
                     PRK05610"
                     /db_xref="CDD:235532"
     gene            186305..186673
                     /gene="rplN"
                     /locus_tag="COSY_0179"
                     /db_xref="GeneID:5172636"
     CDS             186305..186673
                     /gene="rplN"
                     /locus_tag="COSY_0179"
                     /note="binds to the 23S rRNA between the centers for
                     peptidyl transferase and GTPase"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="YP_001219033.1"
                     /db_xref="GI:148244339"
                     /db_xref="GeneID:5172636"
                     /translation="MIQVQTRLKVADNSGGIKAMCIKVLGGSKRRYANIGDVIKVSIK
                     EVVPRGKVKKGDVYDAVVVRTAHGVRRSDGSRIRFDSNAIVLLNTKREPIGTRIFGPV
                     TRELRSAQFMKIVSLAPEVL"
     misc_feature    186305..186670
                     /gene="rplN"
                     /locus_tag="COSY_0179"
                     /note="50S ribosomal protein L14; Validated; Region: rplN;
                     PRK05483"
                     /db_xref="CDD:180117"
     gene            186673..186984
                     /gene="rplX"
                     /locus_tag="COSY_0180"
                     /db_xref="GeneID:5172422"
     CDS             186673..186984
                     /gene="rplX"
                     /locus_tag="COSY_0180"
                     /note="assembly initiator protein; binds to 5' end of 23S
                     rRNA and nucleates assembly of the 50S; surrounds
                     polypeptide exit tunnel"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="YP_001219034.1"
                     /db_xref="GI:148244340"
                     /db_xref="GeneID:5172422"
                     /translation="MQKIKSNDEIIIIAGKDKGSIGIVTKIVDSKVLVEGLNLAKKHV
                     KPNPNKGVTGGITEIEMPLSISNVAIYNPTTKKADRVGIRTSKNGIKERFFKSNDKSI
                     I"
     misc_feature    186673..186978
                     /gene="rplX"
                     /locus_tag="COSY_0180"
                     /note="50S ribosomal protein L24; Reviewed; Region: rplX;
                     PRK00004"
                     /db_xref="CDD:234566"
     misc_feature    186691..186882
                     /gene="rplX"
                     /locus_tag="COSY_0180"
                     /note="KOW motif of Ribosomal Protein L26; Region:
                     KOW_RPL26; cd06089"
                     /db_xref="CDD:240513"
     misc_feature    order(186712..186720,186754..186756,186793..186798,
                     186865..186870)
                     /gene="rplX"
                     /locus_tag="COSY_0180"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:240513"
     gene            187014..187553
                     /gene="rplE"
                     /locus_tag="COSY_0181"
                     /db_xref="GeneID:5172510"
     CDS             187014..187553
                     /gene="rplE"
                     /locus_tag="COSY_0181"
                     /note="part of 50S and 5S/L5/L18/L25 subcomplex; contacts
                     5S rRNA and P site tRNA; forms a bridge to the 30S subunit
                     in the ribosome by binding to S13"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="YP_001219035.1"
                     /db_xref="GI:148244341"
                     /db_xref="GeneID:5172510"
                     /translation="MSRLQEQYKNKISLILQKELGMSNPMQTPKIEKITINMGLGNAL
                     GDKKILQSGLEEMSLISGQKPLTCNARKSVASFKLREGNPIGCKVTLRKQKMYEFLDR
                     LVNITIPRIRDFRGLKTTAFDGRGNYNMGITEQITFPEIDFEKVTKIRGMDIAITTTA
                     KSDEDAKKLLAMFKFPFKG"
     misc_feature    187014..187547
                     /gene="rplE"
                     /locus_tag="COSY_0181"
                     /note="50S ribosomal protein L5; Validated; Region: rplE;
                     PRK00010"
                     /db_xref="CDD:178791"
     misc_feature    187083..187253
                     /gene="rplE"
                     /locus_tag="COSY_0181"
                     /note="Ribosomal protein L5; Region: Ribosomal_L5;
                     pfam00281"
                     /db_xref="CDD:109342"
     misc_feature    187263..187547
                     /gene="rplE"
                     /locus_tag="COSY_0181"
                     /note="ribosomal L5P family C-terminus; Region:
                     Ribosomal_L5_C; pfam00673"
                     /db_xref="CDD:201383"
     gene            187559..187864
                     /gene="rpsN"
                     /locus_tag="COSY_0182"
                     /db_xref="GeneID:5172663"
     CDS             187559..187864
                     /gene="rpsN"
                     /locus_tag="COSY_0182"
                     /note="located in the peptidyl transferase center and
                     involved in assembly of 30S ribosome subunit; similar to
                     what is observed with proteins L31 and L33, some proteins
                     in this family contain CXXC motifs that are involved in
                     zinc binding; if two copies are present in a genome, then
                     the duplicated copy appears to have lost the zinc-binding
                     motif and is instead regulated by zinc; the proteins in
                     this group do not appear to have the zinc-binding motif"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="YP_001219036.1"
                     /db_xref="GI:148244342"
                     /db_xref="GeneID:5172663"
                     /translation="MAKKSMMNRDIKRTKIVKKYKAKRLELKKIIKSINVSDEERFQA
                     TIKLQALPRNASPTRQRSRCSLTGRPHGFYRKFGLARNKLRECTMNGEVPGLSKASW"
     misc_feature    187559..187861
                     /gene="rpsN"
                     /locus_tag="COSY_0182"
                     /note="30S ribosomal protein S14; Reviewed; Region: rpsN;
                     PRK08881"
                     /db_xref="CDD:181574"
     gene            187876..188271
                     /gene="rpsH"
                     /locus_tag="COSY_0183"
                     /db_xref="GeneID:5172600"
     CDS             187876..188271
                     /gene="rpsH"
                     /locus_tag="COSY_0183"
                     /note="binds directly to 16S rRNA central domain where it
                     helps coordinate assembly of the platform of the 30S
                     subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="YP_001219037.1"
                     /db_xref="GI:148244343"
                     /db_xref="GeneID:5172600"
                     /translation="MSMSDPIADMLTRIRNAQLVKKKEVNVPSSNLKFAIAGVMQQEG
                     YIESFSVNGVVASKILKIKLKYYDNKPVIEKLKRISKPSLRVYVSNSKIPSVMNGLGI
                     VIVSTPKGVMTGQVALDQNVGGEVLCSIY"
     misc_feature    187879..188268
                     /gene="rpsH"
                     /locus_tag="COSY_0183"
                     /note="30S ribosomal protein S8; Validated; Region: rpsH;
                     PRK00136"
                     /db_xref="CDD:234658"
     gene            188287..188832
                     /gene="rplF"
                     /locus_tag="COSY_0184"
                     /db_xref="GeneID:5172555"
     CDS             188287..188832
                     /gene="rplF"
                     /locus_tag="COSY_0184"
                     /note="ribosomal protein L6 appears to have arisen as a
                     result of an ancient gene duplication as based on
                     structural comparison of the Bacillus stearothermophilus
                     protein; RNA-binding appears to be in the C-terminal
                     domain; mutations in the L6 gene confer resistance to
                     aminoglycoside antibiotics such as gentamicin and these
                     occur in truncations of the C-terminal domain; it has been
                     localized to a region between the base of the L7/L12 stalk
                     and the central protuberance"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="YP_001219038.1"
                     /db_xref="GI:148244344"
                     /db_xref="GeneID:5172555"
                     /translation="MSRVAKSSITIPTSVEVIITGNLMSVKGRLGQLNMSIHPCVAIM
                     NTNSKLSFDIITIEKKEQRKAWAQAGTARANTANLIQGVTEGWKKKLTLIGVGYRAKV
                     MGKILDLTLGFSHPINYKFPEGIIVETPSQTEIIIKGMDKQKVGQVASEIRSYRPPEP
                     YKGKGVRYIDEQVIHKETKKK"
     misc_feature    188287..188829
                     /gene="rplF"
                     /locus_tag="COSY_0184"
                     /note="50S ribosomal protein L6; Validated; Region: rplF;
                     PRK05498"
                     /db_xref="CDD:235495"
     misc_feature    188566..188790
                     /gene="rplF"
                     /locus_tag="COSY_0184"
                     /note="Ribosomal protein L6; Region: Ribosomal_L6;
                     pfam00347"
                     /db_xref="CDD:215872"
     gene            188850..189197
                     /gene="rplR"
                     /locus_tag="COSY_0185"
                     /db_xref="GeneID:5172669"
     CDS             188850..189197
                     /gene="rplR"
                     /locus_tag="COSY_0185"
                     /note="binds 5S rRNA along with protein L5 and L25"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="YP_001219039.1"
                     /db_xref="GI:148244345"
                     /db_xref="GeneID:5172669"
                     /translation="MKFLKKQARLRRATKFRAKHAKKDIERLCIHKTAQHIYAQIISS
                     CGTKILASASTLKAKLKNGGNVDAAVKVGEAIAKAATSVKVKKVAFDRSGFKYHGRVK
                     ALADAAREGGLDF"
     misc_feature    188928..189188
                     /gene="rplR"
                     /locus_tag="COSY_0185"
                     /note="Ribosomal L18/L5e:  L18 (L5e) is a ribosomal
                     protein found in the central protuberance (CP) of the
                     large subunit. L18 binds 5S rRNA and induces a
                     conformational change that stimulates the binding of L5 to
                     5S rRNA. Association of 5S rRNA with 23S rRNA...; Region:
                     Ribosomal_L18_L5e; cd00432"
                     /db_xref="CDD:238246"
     misc_feature    order(188928..188930,188940..188957,188961..188963,
                     188967..188969,188988..188996,189003..189005,
                     189114..189116,189147..189149)
                     /gene="rplR"
                     /locus_tag="COSY_0185"
                     /note="5S rRNA interface [nucleotide binding]; other site"
                     /db_xref="CDD:238246"
     misc_feature    order(189117..189119,189126..189128,189174..189176)
                     /gene="rplR"
                     /locus_tag="COSY_0185"
                     /note="23S rRNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238246"
     misc_feature    189132..189134
                     /gene="rplR"
                     /locus_tag="COSY_0185"
                     /note="L5 interface [polypeptide binding]; other site"
                     /db_xref="CDD:238246"
     gene            189240..189755
                     /gene="rpsE"
                     /locus_tag="COSY_0186"
                     /db_xref="GeneID:5172428"
     CDS             189240..189755
                     /gene="rpsE"
                     /locus_tag="COSY_0186"
                     /note="located at the back of the 30S subunit body where
                     it stabilizes the conformation of the head with respect to
                     the body; contacts S4 and S8; with S4 and S12 plays a role
                     in translational accuracy; mutations in this gene result
                     in spectinomycin resistance"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="YP_001219040.1"
                     /db_xref="GI:148244346"
                     /db_xref="GeneID:5172428"
                     /translation="MAGYKENNNIDNNYIEKLVNIRRVVKVVKGGRIFGFSALVVVGD
                     GNGKVGYGTGKAREVPVAIQKAMDKARKAMKNVPLVNGTLHYSIISNVGAAKVYMQPA
                     SEGTGVIAGGPMRSVLEAVGVHNILAKCNGTRNPISVVRATVEGLTSMLSPQLVATKR
                     GMTVDQITGEE"
     misc_feature    189243..189746
                     /gene="rpsE"
                     /locus_tag="COSY_0186"
                     /note="30S ribosomal protein S5; Validated; Region: rpsE;
                     PRK00550"
                     /db_xref="CDD:234790"
     misc_feature    <189348..189476
                     /gene="rpsE"
                     /locus_tag="COSY_0186"
                     /note="Ribosomal protein S5, N-terminal domain; Region:
                     Ribosomal_S5; pfam00333"
                     /db_xref="CDD:144065"
     misc_feature    189501..189722
                     /gene="rpsE"
                     /locus_tag="COSY_0186"
                     /note="Ribosomal protein S5, C-terminal domain; Region:
                     Ribosomal_S5_C; pfam03719"
                     /db_xref="CDD:190724"
     gene            189755..189997
                     /gene="rpmD"
                     /locus_tag="COSY_0187"
                     /db_xref="GeneID:5172513"
     CDS             189755..189997
                     /gene="rpmD"
                     /locus_tag="COSY_0187"
                     /note="L30 binds domain II of the 23S rRNA and the 5S
                     rRNA; similar to eukaryotic protein L7"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="YP_001219041.1"
                     /db_xref="GI:148244347"
                     /db_xref="GeneID:5172513"
                     /translation="MAKENRTVKKVTTIQKTQVSSKHNTVSVTLVKSFHGRLPSHRET
                     IVGLGLKRINHTKKFKDTSEIRGMINKVSYLLKVEN"
     misc_feature    189836..189991
                     /gene="rpmD"
                     /locus_tag="COSY_0187"
                     /note="Ribosomal protein L30, which is found in eukaryotes
                     and prokaryotes but not in archaea, is one of the smallest
                     ribosomal proteins with a molecular mass of about 7kDa.
                     L30 binds the 23SrRNA as well as the 5S rRNA and is one of
                     five ribosomal proteins that...; Region: Ribosomal_L30;
                     cd01658"
                     /db_xref="CDD:100100"
     misc_feature    order(189848..189853,189857..189862,189866..189874,
                     189881..189886,189893..189901,189905..189907,
                     189914..189916,189929..189934,189941..189949,
                     189953..189958)
                     /gene="rpmD"
                     /locus_tag="COSY_0187"
                     /note="23S rRNA binding site [nucleotide binding]; other
                     site"
                     /db_xref="CDD:100100"
     gene            190011..190445
                     /gene="rplO"
                     /locus_tag="COSY_0188"
                     /db_xref="GeneID:5172522"
     CDS             190011..190445
                     /gene="rplO"
                     /locus_tag="COSY_0188"
                     /note="late assembly protein"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="YP_001219042.1"
                     /db_xref="GI:148244348"
                     /db_xref="GeneID:5172522"
                     /translation="MQLNTLSPAQGEKKSRKRVGRGIGSGIGKTCGSGHKGQKSRSGG
                     FNKIGFEGGQMPLQRRLPKVGFSSRISIITSQVTLSEINRLTETYITIDVFKAHNLIT
                     KNIKRVKVILSGEITRAVTLTGIKVTKGAKLAIEAVKGSVSD"
     misc_feature    190011..190436
                     /gene="rplO"
                     /locus_tag="COSY_0188"
                     /note="50S ribosomal protein L15; Reviewed; Region: rplO;
                     PRK05592"
                     /db_xref="CDD:235523"
     gene            190446..191747
                     /gene="secY"
                     /locus_tag="COSY_0189"
                     /db_xref="GeneID:5172197"
     CDS             190446..191747
                     /gene="secY"
                     /locus_tag="COSY_0189"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase SecY subunit"
                     /protein_id="YP_001219043.1"
                     /db_xref="GI:148244349"
                     /db_xref="GeneID:5172197"
                     /translation="MMNQPLNLSQDLSKRILFLLGALIIFRLGTHITIPFISSIALAS
                     LVQNQQGTILDMFNMFSGGALERLSIFTLGIMPYISSSIIIQLMTSVVPKLEQLKKEG
                     ETGKRRITQYTRIGTVILAVFQSYGISIALQSQSSGGVTLVTQSGFTFSMVTVVTLTT
                     GTLFLMWLGEQITEKGIGNGISMIIFAGIVSGLPSAFGSTLSLVSTGELSIILVVILL
                     IMTSLVIAFVVFMERGQRRITVNYAKRQRGRKMIGAQSSYLPLKINMAGVIPPIFASS
                     IILFPATLGGWFSRSEGMGWLADITESISPGQPLYVLFYGLAIVFFTFFYTALTFDSK
                     DTADNLRKSGGFIPGIRPGKHSADYIDSVMSRLTASGAVYITAVCLLPEFLILYWNVP
                     FYFGGTSLLIIVVVVMDFIAQAQSHLMSNQYGSLMKKAGLN"
     misc_feature    190476..191726
                     /gene="secY"
                     /locus_tag="COSY_0189"
                     /note="preprotein translocase subunit SecY; Reviewed;
                     Region: secY; PRK09204"
                     /db_xref="CDD:236412"
     misc_feature    190650..191678
                     /gene="secY"
                     /locus_tag="COSY_0189"
                     /note="SecY translocase; Region: SecY; pfam00344"
                     /db_xref="CDD:215869"
     gene            191762..191875
                     /gene="rpmJ"
                     /locus_tag="COSY_0190"
                     /db_xref="GeneID:5171876"
     CDS             191762..191875
                     /gene="rpmJ"
                     /locus_tag="COSY_0190"
                     /note="smallest protein in the large subunit; similar to
                     what is found with protein L31 and L33 several bacterial
                     genomes contain paralogs which may be regulated by zinc;
                     the protein from Thermus thermophilus has a zinc-binding
                     motif and contains a bound zinc ion; the proteins in this
                     group have the motif"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="YP_001219044.1"
                     /db_xref="GI:148244350"
                     /db_xref="GeneID:5171876"
                     /translation="MKVRASVKRICNNCKIIKRHGVVRVICKEPRHKQRQG"
     misc_feature    191762..191872
                     /gene="rpmJ"
                     /locus_tag="COSY_0190"
                     /note="50S ribosomal protein L36; Reviewed; Region: rpmJ;
                     PRK00465"
                     /db_xref="CDD:179039"
     gene            192035..192388
                     /gene="rpsM"
                     /locus_tag="COSY_0191"
                     /db_xref="GeneID:5172161"
     CDS             192035..192388
                     /gene="rpsM"
                     /locus_tag="COSY_0191"
                     /note="located at the top of the head of the 30S subunit,
                     it contacts several helices of the 16S rRNA; makes contact
                     with the large subunit via RNA-protein interactions and
                     via protein-protein interactions with L5; contacts P-site
                     tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="YP_001219045.1"
                     /db_xref="GI:148244351"
                     /db_xref="GeneID:5172161"
                     /translation="MARIAGINIPTHKHIVIGLQSIFGIGDTRAREICITLKLDPVTK
                     VANITENQLELIRVEIAKYEVEGDLRRQLAMDIKRLKDLGCYRGVRHRKSLPLRGQRT
                     KTNARTRKGPRRLIK"
     misc_feature    192035..192385
                     /gene="rpsM"
                     /locus_tag="COSY_0191"
                     /note="30S ribosomal protein S13; Validated; Region: rpsM;
                     PRK05179"
                     /db_xref="CDD:235358"
     misc_feature    192041..192376
                     /gene="rpsM"
                     /locus_tag="COSY_0191"
                     /note="30S ribosomal protein S13; Region: bact_S13;
                     TIGR03631"
                     /db_xref="CDD:213840"
     gene            192407..192793
                     /gene="rpsK"
                     /locus_tag="COSY_0192"
                     /db_xref="GeneID:5171811"
     CDS             192407..192793
                     /gene="rpsK"
                     /locus_tag="COSY_0192"
                     /note="located on the platform of the 30S subunit, it
                     bridges several disparate RNA helices of the 16S rRNA;
                     forms part of the Shine-Dalgarno cleft in the 70S
                     ribosome; interacts with S7 and S18 and IF-3"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="YP_001219046.1"
                     /db_xref="GI:148244352"
                     /db_xref="GeneID:5171811"
                     /translation="MIAKSSSKKKSKKVITDGIAHIHATFNNTIVMITDRHGNTVCWA
                     TSGGSGFRGSRKSTPFAAQVAAGSCGEKALAFGMKNLEVHVKGPGPGRDSAIRGLNAQ
                     GLKIQSITDVTPIPHNGCRPSKKRRV"
     misc_feature    192446..192790
                     /gene="rpsK"
                     /locus_tag="COSY_0192"
                     /note="30S ribosomal protein S11; Validated; Region:
                     PRK05309"
                     /db_xref="CDD:180007"
     gene            192803..193429
                     /gene="rpsD"
                     /locus_tag="COSY_0193"
                     /db_xref="GeneID:5172490"
     CDS             192803..193429
                     /gene="rpsD"
                     /locus_tag="COSY_0193"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="YP_001219047.1"
                     /db_xref="GI:148244353"
                     /db_xref="GeneID:5172490"
                     /translation="MARYTGPTCKLARREGADLFLKSGIRSLDSKCKVTQLPGMHGAS
                     ARRQKGTEYGLQLREKQKIRRIYGILEKQFRLYYKKASQKKGSTGENLLSLLECRLDN
                     VVYRMGFASTRAEARQLVSHKSIMVNGLVVNIPSYQVSVNDKISIREKAKKQSRIQLA
                     LELSGQSTQPQWLDVDNKTLKGVFKNVPSRDELPSDIQEHLIVELYSK"
     misc_feature    192803..193426
                     /gene="rpsD"
                     /locus_tag="COSY_0193"
                     /note="30S ribosomal protein S4; Validated; Region: rpsD;
                     PRK05327"
                     /db_xref="CDD:235411"
     misc_feature    192806..193093
                     /gene="rpsD"
                     /locus_tag="COSY_0193"
                     /note="Ribosomal protein S4/S9 N-terminal domain; Region:
                     Ribosomal_S4; pfam00163"
                     /db_xref="CDD:215762"
     misc_feature    193097..193273
                     /gene="rpsD"
                     /locus_tag="COSY_0193"
                     /note="S4/Hsp/ tRNA synthetase RNA-binding domain; The
                     domain surface is populated by conserved, charged residues
                     that define a likely RNA-binding site;  Found in stress
                     proteins, ribosomal proteins and tRNA synthetases; This
                     may imply a hitherto unrecognized...; Region: S4; cd00165"
                     /db_xref="CDD:238095"
     misc_feature    order(193097..193099,193133..193138,193142..193147,
                     193151..193156,193163..193168,193172..193174,
                     193193..193216,193220..193222)
                     /gene="rpsD"
                     /locus_tag="COSY_0193"
                     /note="RNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238095"
     gene            193440..194420
                     /gene="rpoA"
                     /locus_tag="COSY_0194"
                     /db_xref="GeneID:5172506"
     CDS             193440..194420
                     /gene="rpoA"
                     /locus_tag="COSY_0194"
                     /EC_number="2.7.7.6"
                     /note="catalyzes the transcription of DNA into RNA using
                     the four ribonucleoside triphosphates as substrates.
                     Dimerization of the alpha subunit is the first step in the
                     sequential assembly of subunits to form the holoenzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="YP_001219048.1"
                     /db_xref="GI:148244354"
                     /db_xref="GeneID:5172506"
                     /translation="MQGSARDFLKPKLVESSQTGVNEFKVILEPLERGFGHTLGNAIR
                     RTLLSSMTGFAVTEVVIDGVMHEFSTIDGVQEDVLDILLNLKEVSVVLNTVETAQVVI
                     DKKGPCEITVADIETNGIDITTFNPDKVIATINDEGHMRMTLKITAGIGYDAAASRTD
                     EASSIGGMQLDASFSPIKRVSFTVDAARVKQKVNLDKLNIMIETNGSVNAEVAIKRVA
                     TILQEQLSSFVELELVEEEVSLPTSEDFDPQLLAAVDELELTVRSANCLKAEQIYYIG
                     DLIQKSEQDLLRTPNLGRKSLNEIKEVLTEKGLSLGTNIENWPPVDLMSE"
     misc_feature    193455..194378
                     /gene="rpoA"
                     /locus_tag="COSY_0194"
                     /note="DNA-directed RNA polymerase subunit alpha;
                     Provisional; Region: PRK05182"
                     /db_xref="CDD:235359"
     misc_feature    193479..194099
                     /gene="rpoA"
                     /locus_tag="COSY_0194"
                     /note="N-terminal domain of the Alpha subunit of Bacterial
                     RNA polymerase; Region: RNAP_alpha_NTD; cd06928"
                     /db_xref="CDD:132904"
     misc_feature    order(193479..193481,193485..193487,193521..193523,
                     193530..193532,193536..193544,193551..193553,
                     193563..193565,193572..193577,193587..193589,
                     194091..194093)
                     /gene="rpoA"
                     /locus_tag="COSY_0194"
                     /note="alphaNTD homodimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:132904"
     misc_feature    order(193512..193514,193548..193550,193560..193562,
                     193569..193574,193635..193637,193641..193643,
                     193647..193649,193653..193664,193677..193679,
                     193695..193697,193842..193844,193893..193895,
                     193950..193952,193956..193958,193974..193982,
                     193986..193997,194025..194027,194034..194036,
                     194040..194042)
                     /gene="rpoA"
                     /locus_tag="COSY_0194"
                     /note="alphaNTD - beta interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:132904"
     misc_feature    order(193641..193643,193677..193679,193686..193688,
                     193695..193700,193890..193895,193899..193901,
                     193956..193958,193971..193976,194001..194003)
                     /gene="rpoA"
                     /locus_tag="COSY_0194"
                     /note="alphaNTD - beta' interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:132904"
     misc_feature    194169..194357
                     /gene="rpoA"
                     /locus_tag="COSY_0194"
                     /note="Bacterial RNA polymerase, alpha chain C terminal
                     domain; Region: RNA_pol_A_CTD; pfam03118"
                     /db_xref="CDD:202541"
     gene            194431..194826
                     /gene="rplQ"
                     /locus_tag="COSY_0195"
                     /db_xref="GeneID:5172474"
     CDS             194431..194826
                     /gene="rplQ"
                     /locus_tag="COSY_0195"
                     /note="is a component of the macrolide binding site in the
                     peptidyl transferase center"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="YP_001219049.1"
                     /db_xref="GI:148244355"
                     /db_xref="GeneID:5172474"
                     /translation="MRHRKSGRQLNRNASHRKAMFKNMANSLFLYKTIRTTLPKAKEL
                     RRVVEPLITKAKIDSVANRRNAFSKLRDSAIVAKLFTELAPFYKDRPGGYIRILKAGF
                     RTGDKAAMAIVQLIDLETMTDTTAGTTTS"
     misc_feature    194440..194778
                     /gene="rplQ"
                     /locus_tag="COSY_0195"
                     /note="50S ribosomal protein L17; Validated; Region: rplQ;
                     PRK05591"
                     /db_xref="CDD:235522"
     gene            194838..195053
                     /gene="rpsU"
                     /locus_tag="COSY_0196"
                     /db_xref="GeneID:5172318"
     CDS             194838..195053
                     /gene="rpsU"
                     /locus_tag="COSY_0196"
                     /note="a small basic protein that is one of the last in
                     the subunit assembly; omission does not prevent assembly
                     but the subunit is inactive; binds central domain of 16S
                     rRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="YP_001219050.1"
                     /db_xref="GI:148244356"
                     /db_xref="GeneID:5172318"
                     /translation="MPSIKVRENEPFDIALRRFRRICDRAGVITDVRKKEFFEKPTWV
                     SKRMKAAAVKRTHKEMAKNRVYRKRMY"
     misc_feature    194838..195029
                     /gene="rpsU"
                     /locus_tag="COSY_0196"
                     /note="30S ribosomal protein S21; Reviewed; Region: rpsU;
                     PRK00270"
                     /db_xref="CDD:234707"
     gene            195605..196669
                     /gene="cca"
                     /locus_tag="COSY_0197"
                     /db_xref="GeneID:5172465"
     CDS             195605..196669
                     /gene="cca"
                     /locus_tag="COSY_0197"
                     /EC_number="2.7.7.72"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA nucleotidyltransferase (CCA-adding enzyme)"
                     /protein_id="YP_001219051.1"
                     /db_xref="GI:148244357"
                     /db_xref="GeneID:5172465"
                     /translation="MKIYLVGGAVRDRLLGIADDNTEKDWVVVGSSSTEMLDLGYRQV
                     GKDFPVFLHPDTQEEYALARIERKLGIGYKRFEFDVSSSVTLEQDLSRRDLTINAIAQ
                     KDDELFDPFNGQEDLNNRILRHVSNDFSEDPVRVLRVARFAAYFKNFGFEVEQETYQL
                     MRQMVASGEVDSLTPERVFKELNKALSYGTPSAFFKVLTACGAYQKVFPSLNNHIYQN
                     YSNSFEFLDNLNTKAHIKFSIWLKDENKYNIKCPKQYQQLSELTSQFYKFSKDFINKS
                     SREIFDFFTQTDALRRQDRFEDLLTVFKLLEIDILPIKHLKNLLKNIDISRLDKLDFG
                     KAIQIEKKLIIDSFIRKIKK"
     misc_feature    195605..196636
                     /gene="cca"
                     /locus_tag="COSY_0197"
                     /note="tRNA CCA-pyrophosphorylase; Provisional; Region:
                     PRK13298"
                     /db_xref="CDD:237338"
     misc_feature    195605..195961
                     /gene="cca"
                     /locus_tag="COSY_0197"
                     /note="Nucleotidyltransferase (NT) domain of ClassII
                     CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398"
                     /db_xref="CDD:143388"
     misc_feature    order(195623..195628,195635..195640,195671..195673,
                     195677..195679,195779..195781,195794..195796,
                     195878..195889,195896..195898)
                     /gene="cca"
                     /locus_tag="COSY_0197"
                     /note="active site"
                     /db_xref="CDD:143388"
     misc_feature    order(195623..195628,195635..195637,195671..195673,
                     195677..195679,195878..195886,195896..195898)
                     /gene="cca"
                     /locus_tag="COSY_0197"
                     /note="NTP binding site [chemical binding]; other site"
                     /db_xref="CDD:143388"
     misc_feature    order(195671..195673,195677..195679,195779..195781)
                     /gene="cca"
                     /locus_tag="COSY_0197"
                     /note="metal binding triad [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143388"
     misc_feature    196052..196249
                     /gene="cca"
                     /locus_tag="COSY_0197"
                     /note="Probable RNA and SrmB- binding site of polymerase
                     A; Region: PolyA_pol_RNAbd; pfam12627"
                     /db_xref="CDD:221674"
     gene            complement(196825..199305)
                     /locus_tag="COSY_0198"
                     /db_xref="GeneID:5171915"
     CDS             complement(196825..199305)
                     /locus_tag="COSY_0198"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219052.1"
                     /db_xref="GI:148244358"
                     /db_xref="GeneID:5171915"
                     /translation="MVMLINVDLTKLNAKNIIILANNQQVLAFKKTFTIQHGNSQLPI
                     TLSWKQYLLHTWRQINPNSNLRFIDQIESRYLIKQSIQKLGQKTNHRLLDEVIKNYNY
                     CTNYLIDLSELYRSKIHSSELFSIWINTYQNTKLNLDLIDLQDLPRLIIKAKTSITKP
                     HIYGFKTLTPQQQLLFDIIGYQQISAIKTYNVSALTFDTVTSEIFKAAKWAKTHFDIN
                     PNKSIAIVNPSSNDIKYQLSSIFDQVFGDLLTEIEEKSYTISLGLRLNQYPIIQDLLS
                     ILTLSAQIQHNKIRSTLFNQVVTCVYVFGYQKERSDRNLLKNQVLSLLTDQFNLDKIN
                     EALSKCPILKTIIDNIKCEQLTNNTLESHLLAFNNTLKTWGFATDRNLSNTEYQIFKK
                     YLETSLELNRLSSYYDKVSTQSAIKQLNNLTTQIIFQAQASKTNIQILSVSEAHGLYF
                     DEAWVLGMTNQFVSTQLNLPRFITYDISTKHHIPHTDYKLIATDAKNTLESLNSIAGK
                     VIFSYAATHLGSKQLPSPLVKFDTSINTNHIQKIFPIALESINDTKTTHLEKTQVKSG
                     VCILKDQMACAFKGFIHRLNIPNFDAPHIGINRLEQGYIIHNTLQYIYQKITSKKQLL
                     ALNNKELDKLILNTIKAALRHYPSSSFKKIEKLRLSRLIHSFIAVDKLREDFYILKTE
                     QSITINIANLEFKIRLDRLDQMSNGDKIIFDYKTSSTSIYNWCDTAISKPQLPIYAIT
                     NNVQGAAFIELTSHKINFKGLSEDSDSLPKQSKYKGKCQSWNKQLKIWQNILNTASFD
                     FQNGIAAVLPNKNACDYCKFYLFCRVKK"
     misc_feature    complement(196837..198945)
                     /locus_tag="COSY_0198"
                     /note="probable DNA repair protein; Region: TIGR03623"
                     /db_xref="CDD:234283"
     misc_feature    complement(197092..197586)
                     /locus_tag="COSY_0198"
                     /note="PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1;
                     pfam12705"
                     /db_xref="CDD:221726"
     gene            complement(199289..199888)
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /db_xref="GeneID:5172604"
     CDS             complement(199289..199888)
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /note="binds guanine nucleotides; in Escherichia coli
                     depletion results in defective cell division and
                     filamentation; in Bacillus subtilis this gene is
                     essential"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein YsxC"
                     /protein_id="YP_001219053.1"
                     /db_xref="GI:148244359"
                     /db_xref="GeneID:5172604"
                     /translation="MCKHYHQAKFLLSCPSLKGCPPDQGYEVIFAGRSNAGKSRAINT
                     LTLQNKLAKVSRTPGRTQHLVFFELDKDRRLADLPGYGYAKVPEHIKVKWYKDMNEYF
                     NQRDCLRGAVLVMDVRHPLKPFDQMMLDWCNNIHLPTQIILTKSDKLKKIAASNTYFK
                     VLDQIKKYSYVDVQLFSSLKKQGLKKLWTRLDTFFGYVD"
     misc_feature    complement(199304..199810)
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /note="YihA (EngB) GTPase family; Region: YihA_EngB;
                     cd01876"
                     /db_xref="CDD:206665"
     misc_feature    complement(199772..199795)
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /note="G1 box; other site"
                     /db_xref="CDD:206665"
     misc_feature    complement(order(199355..199360,199448..199450,
                     199454..199456,199658..199660,199706..199714,
                     199721..199729,199769..199789))
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206665"
     misc_feature    complement(199697..199717)
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206665"
     misc_feature    complement(199706..199708)
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /note="G2 box; other site"
                     /db_xref="CDD:206665"
     misc_feature    complement(199649..199660)
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /note="G3 box; other site"
                     /db_xref="CDD:206665"
     misc_feature    complement(order(199565..199570,199577..199621,
                     199640..199651))
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206665"
     misc_feature    complement(199448..199459)
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /note="G4 box; other site"
                     /db_xref="CDD:206665"
     misc_feature    complement(199352..199360)
                     /gene="engB"
                     /locus_tag="COSY_0199"
                     /note="G5 box; other site"
                     /db_xref="CDD:206665"
     gene            199963..200253
                     /locus_tag="COSY_0200"
                     /db_xref="GeneID:5172458"
     CDS             199963..200253
                     /locus_tag="COSY_0200"
                     /note="Similar to cytochrome c family protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219054.1"
                     /db_xref="GI:148244360"
                     /db_xref="GeneID:5172458"
                     /translation="MKRILLVAAIATFTIGFAQADGAEDYASSGCGSCHGSTGISVVP
                     IYPNLAGQNAAYTVKQLKAFQSGTRKDMTMNAMASIIIGKEQSIADFLAIQK"
     misc_feature    199963..200250
                     /locus_tag="COSY_0200"
                     /note="Cytochrome c; Region: Cytochrom_C; cl11414"
                     /db_xref="CDD:245607"
     gene            200362..201003
                     /locus_tag="COSY_0201"
                     /db_xref="GeneID:5172271"
     CDS             200362..201003
                     /locus_tag="COSY_0201"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c, class I"
                     /protein_id="YP_001219055.1"
                     /db_xref="GI:148244361"
                     /db_xref="GeneID:5172271"
                     /translation="MNKLASIFIIVIAFTSVNVFASGDVNKGEVIALTCVACHGVHGN
                     SVVAAFPKLAGQGEGYLLKQLQDFKSNTRQDAIMKGIVASLTENDMENLAAYFSKQTV
                     TQGVTVKSSNIDLGKKLYRGGNKSKNITACIACHGPTGAGIPSARFPALTYQNATYIA
                     KQLINFRQDAYNTQMDTSAPERSNDYEGMMRNITKYLSNVEIEAVSQYIGRLH"
     misc_feature    200362..200727
                     /locus_tag="COSY_0201"
                     /note="Cytochrome c553 [Energy production and conversion];
                     Region: COG2863"
                     /db_xref="CDD:225418"
     misc_feature    <200734..200997
                     /locus_tag="COSY_0201"
                     /note="Cytochrome c; Region: Cytochrom_C; cl11414"
                     /db_xref="CDD:245607"
     gene            201131..202420
                     /gene="tig"
                     /locus_tag="COSY_0202"
                     /db_xref="GeneID:5172594"
     CDS             201131..202420
                     /gene="tig"
                     /locus_tag="COSY_0202"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="YP_001219056.1"
                     /db_xref="GI:148244362"
                     /db_xref="GeneID:5172594"
                     /translation="MKTSLETLKGLSRSLTIDLPIDIFNQKMDKILQKMALEVNIDGF
                     RKGKVPISIVRKRFGNNANSDVINEIVNETLTDALAQVKLTPVAQPVITKVDSNSNKN
                     FSYTVEFEVFPKIKIADFSELSIEQTKVNITKADEQKTLDGLKDRLTEYKAVQCKSKM
                     GDRLSIDFKGLINGETFDGGEAKDFKIVLGKGSMIKGFEEGLIDVAYSSRVVLDLTFP
                     KDYYMDKLASKDVTFEININEIASPKELKLDETFAKKFGEKNMNALRVSMKEQMRVEV
                     DGRIGHLNKNAIFDKLTTANPFNVPQHSIDNEAQNLFKAMQDRMQHQGLSTQGEMPIT
                     AFNDEAQRRVKLGLLVNQISRDYKLSVSMKQIDEKLKEISKTYGENAQQMIDFYNQDP
                     TRKSSIELLVVEKMVQDLILDKAQVTFKQKKFQEITQ"
     misc_feature    201131..202408
                     /gene="tig"
                     /locus_tag="COSY_0202"
                     /note="trigger factor; Provisional; Region: tig; PRK01490"
                     /db_xref="CDD:234956"
     misc_feature    201599..>201793
                     /gene="tig"
                     /locus_tag="COSY_0202"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase;
                     Region: FKBP_C; pfam00254"
                     /db_xref="CDD:215821"
     misc_feature    201911..202363
                     /gene="tig"
                     /locus_tag="COSY_0202"
                     /note="Bacterial trigger factor protein (TF) C-terminus;
                     Region: Trigger_C; pfam05698"
                     /db_xref="CDD:218701"
     gene            202425..203021
                     /gene="clpP"
                     /locus_tag="COSY_0203"
                     /db_xref="GeneID:5172004"
     CDS             202425..203021
                     /gene="clpP"
                     /locus_tag="COSY_0203"
                     /EC_number="3.4.21.92"
                     /note="hydrolyzes proteins to small peptides; with the
                     ATPase subunits ClpA or ClpX, ClpP degrades specific
                     substrates"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="YP_001219057.1"
                     /db_xref="GI:148244363"
                     /db_xref="GeneID:5172004"
                     /translation="MNIKNLNQIPIVVEQSARGERAYDIYSRLLKERIIFLVGPIEDY
                     MANVVVAQLLFLESENPDKDIHLYINSPGGSVSAGLAIYDTMQFIKSDISTLCIGQAA
                     SMGALLLTAGTKGKRFALPNVRCMIHQPLGGFSGQASDVDIHAQEILKVRANLNQIFK
                     LHTGQVIKTIQKDTDRDNFMSADEATKYGLIDKVLAKR"
     misc_feature    202449..203018
                     /gene="clpP"
                     /locus_tag="COSY_0203"
                     /note="Protease subunit of ATP-dependent Clp proteases
                     [Posttranslational modification, protein turnover,
                     chaperones / Intracellular trafficking and secretion];
                     Region: ClpP; COG0740"
                     /db_xref="CDD:223811"
     misc_feature    202494..203006
                     /gene="clpP"
                     /locus_tag="COSY_0203"
                     /note="Caseinolytic protease (ClpP) is an ATP-dependent,
                     highly conserved serine protease; Region: S14_ClpP_2;
                     cd07017"
                     /db_xref="CDD:132928"
     misc_feature    order(202530..202532,202536..202538,202563..202568,
                     202575..202580,202587..202589,202632..202634,
                     202653..202655,202665..202667,202674..202676,
                     202683..202688,202698..202700,202722..202724,
                     202788..202790,202794..202796,202812..202823,
                     202863..202865,202872..202874,202878..202880,
                     202884..202886,202953..202955,202959..202961)
                     /gene="clpP"
                     /locus_tag="COSY_0203"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:132928"
     misc_feature    order(202731..202733,202806..202808,202953..202955)
                     /gene="clpP"
                     /locus_tag="COSY_0203"
                     /note="active site residues [active]"
                     /db_xref="CDD:132928"
     gene            202996..204291
                     /gene="clpX"
                     /locus_tag="COSY_0204"
                     /db_xref="GeneID:5172112"
     CDS             202996..204291
                     /gene="clpX"
                     /locus_tag="COSY_0204"
                     /note="binds and unfolds substrates as part of the ClpXP
                     protease"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="YP_001219058.1"
                     /db_xref="GI:148244364"
                     /db_xref="GeneID:5172112"
                     /translation="MIKYWQSAKFMKDDNQELVCSFCGKIKSKVERLIAGPGVYICNE
                     CIRSCHDLIEKQALQEVIDEFKNWDYTPKQLTSFLNDYVIGQEHAKKVLSVAVYNHYK
                     RLQNDHISNEVELDKSNILMIGPTGSGKTLLAQTLARILDIPFTVADATTLTEAGYVG
                     DDVENVVKNLLSKCDFDPDRAQRGIIFIDEIDKISRRSDSPSITRDVSGEGVQQAMLK
                     LIEGTIASVPPQGGRKHPNQETIDVDTSNILFICGGAFDGLDKIINRRVKKVTGIGFS
                     VDVKDQNEEKALSDLFVLIQPEDLIKFGLIPELVGRLPVQTVLSELDEIALVKILIEP
                     KNSVIKQFQEIFSMEGVKLIFKKPSLLAIAKLAIKRKTGARGLRSILEDLLLDTMFEL
                     PSLLDVTEVVIDKTVVEKKKKPLIVYQSQKRVNNSKKVG"
     misc_feature    203026..204261
                     /gene="clpX"
                     /locus_tag="COSY_0204"
                     /note="ATP-dependent protease ATP-binding subunit ClpX;
                     Provisional; Region: clpX; PRK05342"
                     /db_xref="CDD:235422"
     misc_feature    203047..203163
                     /gene="clpX"
                     /locus_tag="COSY_0204"
                     /note="ClpX C4-type zinc finger; Region: zf-C4_ClpX;
                     pfam06689"
                     /db_xref="CDD:203502"
     misc_feature    203245..>203667
                     /gene="clpX"
                     /locus_tag="COSY_0204"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    203365..203388
                     /gene="clpX"
                     /locus_tag="COSY_0204"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(203368..203391,203560..203562)
                     /gene="clpX"
                     /locus_tag="COSY_0204"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    203548..203565
                     /gene="clpX"
                     /locus_tag="COSY_0204"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    203959..204222
                     /gene="clpX"
                     /locus_tag="COSY_0204"
                     /note="C-terminal, D2-small domain, of ClpB protein;
                     Region: ClpB_D2-small; smart01086"
                     /db_xref="CDD:198154"
     gene            204729..207065
                     /gene="lon"
                     /locus_tag="COSY_0205"
                     /db_xref="GeneID:5172117"
     CDS             204729..207065
                     /gene="lon"
                     /locus_tag="COSY_0205"
                     /EC_number="3.4.21.53"
                     /note="ATP-dependent Lon protease"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease La"
                     /protein_id="YP_001219059.1"
                     /db_xref="GI:148244365"
                     /db_xref="GeneID:5172117"
                     /translation="MATELNNEQIDLSKSNIPLLPLRDVVVFPHTVMPLFVGRKTSVN
                     AITRAMATNKYIFLVTQKDDQVESPTGDDLHQVGTLATILQMLKLPDGTIKVLVEGVR
                     RAKIKQIVETDGFFEVSLSEFSLQSNDDTEIKAMMRLALDSFENYIKLNKRVPEEVLK
                     MLQEVSNVERFSDVIIANLNLKVSEKQALLSDDKAQDRLDKILSVIQGEIDVLGTEKK
                     IQSRVRKQMESNQRDYYLNEQMKSIQKELGQAEDENEIEELQVGINKAKMSKEAKEKA
                     QNELKKLSRMSSHSSDASIIRTYIENLCDVPWKKKTVINKDLNKAQKILDDDHYSLNK
                     VKERILEHLAVQTRVTHNKANILCLVGPPGVGKTSLGESIARAVNRKYVRMALGGVRD
                     EAEIRGHRRTYIGAMPGSIIQKMQKVKVKNPLFLLDEIEKMASDYRGDPSSAMLEVLD
                     PEQNHTFNDHYLEVDYDLSQVMFVATANSLDLPQPLLDRMEIIELSGYTEDEKVEIAK
                     RHLIKKAMNGNGVKDNEIKFQDDAILDIIRYYTREAGVRGLSRTISTICRKVVKEVIL
                     KKCETKAYINAKSLEKYLGVRKFRFGLAEQNNQIGEVTGLAWTSVGGDLLTIEATAYK
                     GKGKLNYTGQLGDVMQESIQAAKSVVRSMVKKFGIDENFDEKLDIHIHVPDGATPKDG
                     PSAGAAMTTALVSVLTSRKVKADVAMTGEITLRGEVTPIGGLKEKMLAALRGGIKTVI
                     IPDDNERELSEVPEKIKGKLKVIQVKWIDEVLDIALEK"
     misc_feature    204768..207062
                     /gene="lon"
                     /locus_tag="COSY_0205"
                     /note="ATP-dependent Lon protease, bacterial type
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: Lon; COG0466"
                     /db_xref="CDD:223542"
     misc_feature    204777..>204920
                     /gene="lon"
                     /locus_tag="COSY_0205"
                     /note="Found in ATP-dependent protease La (LON); Region:
                     LON; smart00464"
                     /db_xref="CDD:197740"
     misc_feature    205734..206207
                     /gene="lon"
                     /locus_tag="COSY_0205"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    205809..205832
                     /gene="lon"
                     /locus_tag="COSY_0205"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(205812..205835,206010..206012,206151..206153)
                     /gene="lon"
                     /locus_tag="COSY_0205"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    205998..206015
                     /gene="lon"
                     /locus_tag="COSY_0205"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    206193..206195
                     /gene="lon"
                     /locus_tag="COSY_0205"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    206451..207062
                     /gene="lon"
                     /locus_tag="COSY_0205"
                     /note="Lon protease (S16) C-terminal proteolytic domain;
                     Region: Lon_C; pfam05362"
                     /db_xref="CDD:191262"
     gene            complement(207072..207485)
                     /locus_tag="COSY_0206"
                     /db_xref="GeneID:5172289"
     CDS             complement(207072..207485)
                     /locus_tag="COSY_0206"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219060.1"
                     /db_xref="GI:148244366"
                     /db_xref="GeneID:5172289"
                     /translation="MKRILFSITILILLTLNAQAVNQKYVIQISTDDIRTQKIVLNNA
                     VNLQKYYGIDNVDIEIVAYGPGLSILTQSNKNSDRIESMIMNNITFSACHNTMKAIKR
                     KKGKFPTLVEGINIVTSGVVRIGNLQQQGYSYIRP"
     misc_feature    complement(207075..207416)
                     /locus_tag="COSY_0206"
                     /note="DsrE/DsrF-like family; Region: DrsE; pfam02635"
                     /db_xref="CDD:217157"
     gene            208001..209440
                     /gene="pepA"
                     /locus_tag="COSY_0207"
                     /db_xref="GeneID:5172182"
     CDS             208001..209440
                     /gene="pepA"
                     /locus_tag="COSY_0207"
                     /EC_number="3.4.11.1"
                     /note="cytosol aminopeptidase"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="YP_001219061.1"
                     /db_xref="GI:148244367"
                     /db_xref="GeneID:5172182"
                     /translation="MKFTLINEIIQHFKGDAVVVFSNSNTVFNDDNIQQLIKLNHFDS
                     KPGKVLLLNLVSGFKSKQVIVSGLGDAPISAKNYVKALNAVIVILVEIKAKNLMVQHV
                     GIKGFNELWVHEITAKVMCNATYKVQKVGNYKKQNSGIERITIQSTMDSVYGLMKGQA
                     IADGMSLTRHLGDLPSNVCTPSYLAGTAISLAQEFNLECEVLEEVDMEKLGMGSLLAV
                     SKGSSEPPKLISLSYRGNGNEKPIVLVGKGVTFDSGGISLKPGTGMDEMKYDMCGAAS
                     VLGVMRVIAQIKPNINLVVVLPAVENMPAHNASKPGDVVKSMSGKTIEILNTDAEGRL
                     ILCDALTYVKKFNPEVVIDIATLTGAVVVALGKYNSGLMSNDKNLANDIISASKVSLD
                     GVWQLPIEDEYDELLQSNFADMANIGGSSEAGSITAGCFLSRFTQGYRWAHLDIAGTA
                     WVSGDKKGATGRPVSLLTQFIMDQVQKRL"
     misc_feature    208001..209419
                     /gene="pepA"
                     /locus_tag="COSY_0207"
                     /note="multifunctional aminopeptidase A; Provisional;
                     Region: PRK00913"
                     /db_xref="CDD:234863"
     misc_feature    208097..209413
                     /gene="pepA"
                     /locus_tag="COSY_0207"
                     /note="Cytosol aminopeptidase family, N-terminal and
                     catalytic domains.  Family M17 contains zinc- and
                     manganese-dependent exopeptidases ( EC  3.4.11.1),
                     including leucine aminopeptidase. They catalyze removal of
                     amino acids from the N-terminus of a protein and...;
                     Region: Peptidase_M17; cd00433"
                     /db_xref="CDD:238247"
     misc_feature    order(208115..208120,208160..208162,208184..208186,
                     208226..208228,208517..208519,208523..208531,
                     208661..208663,208667..208669,208751..208753,
                     208769..208771,208784..208786,208793..208795,
                     208802..208807,208901..208903,208907..208918,
                     208922..208924,208928..208942,208958..208960,
                     208964..208966,208976..208978,209084..209098,
                     209105..209107,209183..209188,209192..209194,
                     209207..209209,209213..209218,209231..209233,
                     209237..209239,209267..209272,209276..209278,
                     209369..209371)
                     /gene="pepA"
                     /locus_tag="COSY_0207"
                     /note="interface (dimer of trimers) [polypeptide binding];
                     other site"
                     /db_xref="CDD:238247"
     misc_feature    order(208739..208741,208754..208756,208775..208777,
                     208808..208810,208985..208987,208991..208993,
                     208997..208999,209069..209071)
                     /gene="pepA"
                     /locus_tag="COSY_0207"
                     /note="Substrate-binding/catalytic site; other site"
                     /db_xref="CDD:238247"
     misc_feature    order(208739..208741,208754..208756,208808..208810,
                     208985..208987,208991..208993)
                     /gene="pepA"
                     /locus_tag="COSY_0207"
                     /note="Zn-binding sites [ion binding]; other site"
                     /db_xref="CDD:238247"
     gene            complement(210371..210991)
                     /locus_tag="COSY_0208"
                     /db_xref="GeneID:5171865"
     CDS             complement(210371..210991)
                     /locus_tag="COSY_0208"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219062.1"
                     /db_xref="GI:148244368"
                     /db_xref="GeneID:5171865"
                     /translation="MSGIINLIKWLLIIIGAITIYYTVSLQIKYDGITGKVISEIISP
                     KLHPKSMSKVYMPMINTLLDTGDIAMASIVRVKVADDVSNEDVEEAMESIATAKGIRS
                     VGMLPLSEMVELQTNDKQRFLKIYQYCSPRTAMTMVDHSDAFSAYLPCRLALIEDKSG
                     QRWLYMLNMNAMIYGGAPLPDYLLKKALVIQRAMTVIQNNGAKGDF"
     misc_feature    complement(210485..210649)
                     /locus_tag="COSY_0208"
                     /note="Domain of unknown function DUF302; Region: DUF302;
                     pfam03625"
                     /db_xref="CDD:202704"
     gene            complement(211096..211500)
                     /locus_tag="COSY_0209"
                     /db_xref="GeneID:5172610"
     CDS             complement(211096..211500)
                     /locus_tag="COSY_0209"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219063.1"
                     /db_xref="GI:148244369"
                     /db_xref="GeneID:5172610"
                     /translation="MTNNTTTTIVKDVMWTQVDIVNSKCTVQNALNDMQHKKTKMLLV
                     DKSHVYDEYGVVLISDIASKVIAKDRALDRVNVYEIMNKPAISVHSNMDIRYCAKLLT
                     NFNLSRCPVLDNGKIVGMVSLTSIVFNSLRIV"
     misc_feature    complement(211120..211473)
                     /locus_tag="COSY_0209"
                     /note="FOG: CBS domain [General function prediction only];
                     Region: COG0517"
                     /db_xref="CDD:223591"
     misc_feature    complement(211114..211455)
                     /locus_tag="COSY_0209"
                     /note="The CBS domain, named after human CBS, is a small
                     domain originally identified in cystathionine
                     beta-synthase and is subsequently found in a wide range of
                     different proteins. CBS domains usually occur in tandem
                     repeats. They associate to form a so-called...; Region:
                     CBS_pair_17; cd04630"
                     /db_xref="CDD:240001"
     gene            complement(211500..211850)
                     /locus_tag="COSY_0210"
                     /db_xref="GeneID:5172630"
     CDS             complement(211500..211850)
                     /locus_tag="COSY_0210"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein PII"
                     /protein_id="YP_001219064.1"
                     /db_xref="GI:148244370"
                     /db_xref="GeneID:5172630"
                     /translation="MHFKLIIAFVDSNKTDNILEAARTKGATGSTIISQARGEGLKHN
                     KTFLGLNIETPRDVLLLLVERHLSRDILETIADTGNFESNPKEGIAFQVDVEDAVGVM
                     HQIHALEHTIKEKI"
     misc_feature    complement(211548..211835)
                     /locus_tag="COSY_0210"
                     /note="Nitrogen regulatory protein P-II; Region: P-II;
                     smart00938"
                     /db_xref="CDD:198006"
     gene            complement(211859..212599)
                     /locus_tag="COSY_0211"
                     /db_xref="GeneID:5172664"
     CDS             complement(211859..212599)
                     /locus_tag="COSY_0211"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219065.1"
                     /db_xref="GI:148244371"
                     /db_xref="GeneID:5172664"
                     /translation="MNLMGNFINMFWDIMPIAVILLGFQIIILKQKIPYLKKIITGFI
                     LVWIGLTLFIVGLETALFPLGKLMAKQLTSSNFIGNDTLSWKDYYWIYIFAASIGFAT
                     TIAEPALLAIAIKANQVSGGFIKVWPLRIVVAIGVAVGITIGSFRIVTGLPLYYFIIS
                     GYVIVLIQTYFAPKNIIALAYDSGGVTTSTVTVPLVAALGLGLASTIDGRSTLIDGFG
                     LIAFASLFPIMSVMTYVQIIKFLNQNKK"
     misc_feature    complement(211886..212551)
                     /locus_tag="COSY_0211"
                     /note="Protein of unknown function (DUF1538); Region:
                     DUF1538; pfam07556"
                     /db_xref="CDD:148909"
     gene            complement(212596..213327)
                     /locus_tag="COSY_0212"
                     /db_xref="GeneID:5172219"
     CDS             complement(212596..213327)
                     /locus_tag="COSY_0212"
                     /note="Similar to PTS system mannose-specific factor IIC."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219066.1"
                     /db_xref="GI:148244372"
                     /db_xref="GeneID:5172219"
                     /translation="MKKTVQQFTKNLTDSAKDLAPIIGVITFFQIIVLQQSIPNLMDI
                     IIGTGFVLLGLTLFVYGLKLGLFPIGETLAYGFVKKGSIFWLLLFSFALGFGTTVAEP
                     ALIAITNEAAKVAKLGGIVNTQTEINNYAKTLRLTVAISVGLAVVIGVLRILKGWPIQ
                     YLIISGYLLVIATTFFAPDFIIGFAYDSGGVTTSTITVPLLTALGVGLASSISGRNPL
                     TDGFGMIAIASLLPIIAVMLFGILQ"
     misc_feature    complement(212602..213264)
                     /locus_tag="COSY_0212"
                     /note="Protein of unknown function (DUF1538); Region:
                     DUF1538; pfam07556"
                     /db_xref="CDD:148909"
     gene            213433..214320
                     /gene="pabC"
                     /locus_tag="COSY_0213"
                     /db_xref="GeneID:5171853"
     CDS             213433..214320
                     /gene="pabC"
                     /locus_tag="COSY_0213"
                     /EC_number="4.1.3.38"
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxychorismate lyase"
                     /protein_id="YP_001219067.1"
                     /db_xref="GI:148244373"
                     /db_xref="GeneID:5171853"
                     /translation="MVTILLINGKKQTKLSMFNRLVQFGDGLFETCLIEDSRLLFWSK
                     HFLRLEKGCEKLGIHKVNEGIWLKEVAQAFALSRLNQAVVKIILSRGESTRGYGYEKN
                     IKPTRIIIIYPMTDLPWQYELGVCSSGYVGNQLLSEIKHCNRLEQILARSELQGQECI
                     MLDENSLVISVTQGNIFAISNQVILTPSLTNCGIEGTLRSVVFDLAKELDLQLKICSL
                     SLVELLETDEVFITNSVIGIKPVSKINQKLFNHHQITDRLISAFVCSKNNHSLSILLK
                     SKSFYLRFIFIFVAIFLLF"
     misc_feature    213448..214206
                     /gene="pabC"
                     /locus_tag="COSY_0213"
                     /note="Branched-chain amino acid
                     aminotransferase/4-amino-4-deoxychorismate lyase [Amino
                     acid transport and metabolism / Coenzyme metabolism];
                     Region: IlvE; COG0115"
                     /db_xref="CDD:223193"
     misc_feature    213487..214206
                     /gene="pabC"
                     /locus_tag="COSY_0213"
                     /note="ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a
                     member of the fold-type IV of PLP dependent enzymes that
                     converts 4-amino-4-deoxychorismate (ADC) to
                     p-aminobenzoate and pyruvate.  Based on the information
                     available from the crystal structure, most...; Region:
                     ADCL_like; cd01559"
                     /db_xref="CDD:238800"
     misc_feature    order(213574..213576,213850..213852,213940..213942)
                     /gene="pabC"
                     /locus_tag="COSY_0213"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238800"
     misc_feature    213850..213852
                     /gene="pabC"
                     /locus_tag="COSY_0213"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238800"
     gene            214675..215292
                     /gene="tmk"
                     /locus_tag="COSY_0214"
                     /db_xref="GeneID:5171894"
     CDS             214675..215292
                     /gene="tmk"
                     /locus_tag="COSY_0214"
                     /EC_number="2.7.4.9"
                     /note="catalyzes the reversible phosphoryl transfer from
                     adenosine triphosphate (ATP) to thymidine monophosphate
                     (dTMP) to form thymidine diphosphate (dTDP)"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="YP_001219068.1"
                     /db_xref="GI:148244374"
                     /db_xref="GeneID:5171894"
                     /translation="MQRGKFITIDGVEGAGKSTQIDFICSYLAKKNINVVLTREPGGT
                     KLGEKIRALLLSIDTQLMDNDTELLLIFAARNEHIKTKIIPALNRGDWVLSDRFTDAS
                     YAYQGGGRGLSIERIALLEQWVLQDFSPDVTLLLDVPVALGMLRIKSRSRKDRIELET
                     NDFFNRVRDSYIKRSKQFPERIKLIDASQTLKETTQQIKVILQAL"
     misc_feature    214681..215289
                     /gene="tmk"
                     /locus_tag="COSY_0214"
                     /note="thymidylate kinase; Validated; Region: tmk;
                     PRK00698"
                     /db_xref="CDD:234814"
     misc_feature    214687..215283
                     /gene="tmk"
                     /locus_tag="COSY_0214"
                     /note="Thymidine monophosphate kinase (TMPK), also known
                     as thymidylate kinase, catalyzes the phosphorylation of
                     thymidine monophosphate (TMP) to thymidine diphosphate
                     (TDP) utilizing ATP as its preferred phophoryl donor. TMPK
                     represents the rate-limiting step...; Region: TMPK;
                     cd01672"
                     /db_xref="CDD:238835"
     misc_feature    order(214726..214728,214885..214887,214897..214899,
                     214960..214965,214987..214989,215122..215124)
                     /gene="tmk"
                     /locus_tag="COSY_0214"
                     /note="TMP-binding site; other site"
                     /db_xref="CDD:238835"
     misc_feature    order(214729..214731,215110..215112,215233..215235)
                     /gene="tmk"
                     /locus_tag="COSY_0214"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238835"
     gene            215289..216317
                     /gene="holB"
                     /locus_tag="COSY_0215"
                     /db_xref="GeneID:5171888"
     CDS             215289..216317
                     /gene="holB"
                     /locus_tag="COSY_0215"
                     /EC_number="2.7.7.7"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III delta prime subunit"
                     /protein_id="YP_001219069.1"
                     /db_xref="GI:148244375"
                     /db_xref="GeneID:5171888"
                     /translation="MNLPWHKNAWSKLQNMIDQDCFPHALLITGVEKIGKFELMQQLV
                     GVLLKDDIIIRKDNVRNNLDYPVLIRRSNYPNMVYCRAGEMVEKNKNRSNNIRIDQVR
                     VFCDALNKTADELQIGVIFYGDQMNIGAANGLLKTLEEPRKNTLIIILAHHVENLPIT
                     IVSRCQNIHITPTYDQQTCQWLIEHIGKTQKKDYNIKQLLESTHGVPFKVLSDLSDGN
                     FTHYQNYQNQLLNIVANPLMIVQIKDFEGNELVILNCLQNIIIEGIRLKTVHQEDAIT
                     ELYQVIVTVKFEFLFKLLDDIYHAIKLLKTTVNISLLMDNILIVWSHIVHLKKYPQIT
                     NKHVKIIF"
     misc_feature    215316..215909
                     /gene="holB"
                     /locus_tag="COSY_0215"
                     /note="DNA polymerase III, delta&apos; subunit; Region:
                     holB; TIGR00678"
                     /db_xref="CDD:233087"
     misc_feature    <215667..>215780
                     /gene="holB"
                     /locus_tag="COSY_0215"
                     /note="DNA polymerase III subunit delta&apos;; Validated;
                     Region: PRK08485"
                     /db_xref="CDD:236274"
     misc_feature    <215682..216287
                     /gene="holB"
                     /locus_tag="COSY_0215"
                     /note="DNA polymerase III subunits gamma and tau;
                     Provisional; Region: PRK14961"
                     /db_xref="CDD:184925"
     gene            216332..217618
                     /gene="hemL"
                     /locus_tag="COSY_0216"
                     /db_xref="GeneID:5172683"
     CDS             216332..217618
                     /gene="hemL"
                     /locus_tag="COSY_0216"
                     /EC_number="5.4.3.8"
                     /note="Converts (S)-4-amino-5-oxopentanoate to
                     5-aminolevulinate during the porphyrin biosynthesis
                     pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde aminotransferase"
                     /protein_id="YP_001219070.1"
                     /db_xref="GI:148244376"
                     /db_xref="GeneID:5172683"
                     /translation="MNQSEVLFAQARTVISGGVNSPVRAFNGVGGNPIFFTRGKGAYL
                     FDVDGNKYIDYVASWGPMILGHANQEVINAIKTNLENGLSFGAPTHIETMLAEKVCEL
                     IPSIELVRMVSSGTEATMSAIRLARGYTGRDKIIKFEGCYHGHSDALLVKAGSAALTL
                     GVPTSPGVPKDFAKHTLTLEYNNINQVYEILKEVGTEVACIIVEPVAGNMNCILPIDG
                     FLQGLRKLCDEYGIILIFDEVMTGFRVALGGAQEFYNVEPDLTTLGKIIGGGLPVGIF
                     GGKCEIMKCIAPLGPIYQAGTLSGNPISMSAGLAMLNVLSKDKNFYTTLNIKVQKLTK
                     GFLAKAKENNIGMTANVVGGMFGLFFTDAKSVTNFKEVSQCNVELFKRFYHLMLEEGV
                     YMTPSIYETDFISSAHSDMDIQNTIDAAGRVFAKLV"
     misc_feature    216332..217612
                     /gene="hemL"
                     /locus_tag="COSY_0216"
                     /note="glutamate-1-semialdehyde aminotransferase;
                     Provisional; Region: PRK00062"
                     /db_xref="CDD:234607"
     misc_feature    216350..217603
                     /gene="hemL"
                     /locus_tag="COSY_0216"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     Region: OAT_like; cd00610"
                     /db_xref="CDD:99735"
     misc_feature    order(216671..216679,216755..216760,216764..216766,
                     216941..216943,217040..217042,217046..217051,
                     217124..217126)
                     /gene="hemL"
                     /locus_tag="COSY_0216"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99735"
     misc_feature    order(216674..216679,216755..216760,216941..216943,
                     217040..217042,217049..217051,217124..217126)
                     /gene="hemL"
                     /locus_tag="COSY_0216"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99735"
     misc_feature    217124..217126
                     /gene="hemL"
                     /locus_tag="COSY_0216"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     gene            217973..218626
                     /locus_tag="COSY_0217"
                     /db_xref="GeneID:5172408"
     CDS             217973..218626
                     /locus_tag="COSY_0217"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="YP_001219071.1"
                     /db_xref="GI:148244377"
                     /db_xref="GeneID:5172408"
                     /translation="MTLAIFDLDRTLIKGDSDFLWGEFLSEIGAVDVNIYQSKNQYFF
                     DQYMLRKLDIHEYLEFCLEPLSKYSMEILNQWHQWFMDQKIEQILLPKAQLVVDKHKE
                     KGDTLMVITSTNRFVTEPIVARYGIKHLLATNPEIKEGQYTGKVKGEPCFQFGKINHL
                     NKWLKKTSLSIKGASFYSDSYNDLPMLELVDYPIVVHGDDKLNAIAIERGWRCLDWT"
     misc_feature    217973..218605
                     /locus_tag="COSY_0217"
                     /note="Phosphoserine phosphatase [Amino acid transport and
                     metabolism]; Region: SerB; COG0560"
                     /db_xref="CDD:223634"
     misc_feature    217979..218578
                     /locus_tag="COSY_0217"
                     /note="haloacid dehalogenase-like hydrolase; Region: HAD;
                     cl17202"
                     /db_xref="CDD:247756"
     gene            complement(218722..219237)
                     /locus_tag="COSY_0218"
                     /db_xref="GeneID:5171863"
     CDS             complement(218722..219237)
                     /locus_tag="COSY_0218"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219072.1"
                     /db_xref="GI:148244378"
                     /db_xref="GeneID:5171863"
                     /translation="MSDNKKMTIIATKGTFDWAFPPFIIASTGVAMDKEVTIFFTFYG
                     LNLLLKDTSKLRISPIGNPAMPMKLPIGPEWLQKIDFSPKIPNIFWLLPFTEHLATYL
                     MKKTMKKNGVATLDELRSMCQEFDVKFIACEMTVDLFGYSKDDFIDGVEFAGAATYFE
                     ECNDSNHNLYM"
     misc_feature    complement(218728..219231)
                     /locus_tag="COSY_0218"
                     /note="DsrE/DsrF/DrsH-like family; Region: DrsE_2;
                     pfam13686"
                     /db_xref="CDD:205862"
     gene            complement(219266..219490)
                     /locus_tag="COSY_0219"
                     /db_xref="GeneID:5171901"
     CDS             complement(219266..219490)
                     /locus_tag="COSY_0219"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219073.1"
                     /db_xref="GI:148244379"
                     /db_xref="GeneID:5171901"
                     /translation="MADETLDASGLNCPLPILKTKKALSKMDIGKILDVISTDAGSVK
                     DIEAFCNQTGNKLMSAVEESGKYIFTIEKT"
     misc_feature    complement(219272..219478)
                     /locus_tag="COSY_0219"
                     /note="SirA, YedF, and YeeD. Two-layered alpha/beta
                     sandwich domain.  SirA (also known as UvrY,  and YhhP)
                     belongs to a family of bacterial two-component response
                     regulators that controls secondary metabolism and
                     virulence. The other member of this...; Region:
                     SirA_YedF_YeeD; cd00291"
                     /db_xref="CDD:238180"
     misc_feature    complement(order(219437..219439,219443..219454,
                     219461..219463,219470..219475))
                     /locus_tag="COSY_0219"
                     /note="CPxP  motif; other site"
                     /db_xref="CDD:238180"
     gene            complement(220337..220999)
                     /gene="rpiA"
                     /locus_tag="COSY_0220"
                     /db_xref="GeneID:5171991"
     CDS             complement(220337..220999)
                     /gene="rpiA"
                     /locus_tag="COSY_0220"
                     /EC_number="5.3.1.6"
                     /note="Catalyzes D-ribose 5-phosphate --> D-ribulose
                     5-phosphate in the nonoxidative branch of the pentose
                     phosphate pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase A"
                     /protein_id="YP_001219074.1"
                     /db_xref="GI:148244380"
                     /db_xref="GeneID:5171991"
                     /translation="MTQDEMKFTVAQTALKYVIKNTIIGVGTGSTANFFIDALSTIKN
                     NIKGAVASSKATAQRLENHGIRVFDLNKVTAISTYIDGADESDNNLNLIKGGGGALTR
                     EKIVAAVAHQFICIADESKLVSIMGSFPLPIEVIPMAANYVKNQISQKIGGIPEVRKD
                     FITDNGNFILDIKDLKITNPKAMETKLNSIIGVVTNGLFANRGANVLLLGTPNGVKII
                     TN"
     misc_feature    complement(220367..220984)
                     /gene="rpiA"
                     /locus_tag="COSY_0220"
                     /note="RPI_A: Ribose 5-phosphate isomerase type A (RPI_A)
                     subfamily; RPI catalyzes the reversible conversion of
                     ribose-5-phosphate to ribulose 5-phosphate, the first step
                     of the non-oxidative branch of the pentose phosphate
                     pathway. This reaction leads to the...; Region: RPI_A;
                     cd01398"
                     /db_xref="CDD:238692"
     misc_feature    complement(order(220496..220498,220508..220510,
                     220514..220516,220523..220528,220709..220714,
                     220793..220795,220799..220801,220826..220831,
                     220838..220840,220916..220918))
                     /gene="rpiA"
                     /locus_tag="COSY_0220"
                     /note="tetramer (dimer of dimers) interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:238692"
     misc_feature    complement(order(220637..220639,220691..220693,
                     220709..220720,220748..220750,220754..220759,
                     220907..220912,220916..220918))
                     /gene="rpiA"
                     /locus_tag="COSY_0220"
                     /note="active site"
                     /db_xref="CDD:238692"
     misc_feature    complement(order(220418..220420,220433..220438,
                     220565..220567,220574..220582,220586..220591,
                     220673..220675,220694..220696,220778..220780,
                     220790..220792))
                     /gene="rpiA"
                     /locus_tag="COSY_0220"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238692"
     gene            221042..221632
                     /locus_tag="COSY_0221"
                     /db_xref="GeneID:5172635"
     CDS             221042..221632
                     /locus_tag="COSY_0221"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine triphosphate pyrophosphatase"
                     /protein_id="YP_001219075.1"
                     /db_xref="GI:148244381"
                     /db_xref="GeneID:5172635"
                     /translation="MKKIILASNNQGKIKEFNTMLRGIYQVISMKDKQIKEVPEVGLT
                     FVENALIKARNSSEQSGLPALADDSGIVIDALGGNPGIYSARYANCHGDDEANIQKVL
                     IDMKDVVDGERTGRFWCAIVFVEYASDPTPIIIQQSWEGEILREKIGNNGFGYDPIFY
                     VPIYNCTSAELSFVTKNKISHRGKALSALLKVLKKN"
     misc_feature    221051..221590
                     /locus_tag="COSY_0221"
                     /note="NTPase/HAM1.  This family consists of the HAM1
                     protein and pyrophosphate-releasing xanthosine/ inosine
                     triphosphatase. HAM1 protects the cell against mutagenesis
                     by the base analog 6-N-hydroxylaminopurine (HAP) in E.
                     Coli and S. cerevisiae. A...; Region: HAM1; cd00515"
                     /db_xref="CDD:238285"
     misc_feature    order(221069..221071,221075..221080,221087..221089,
                     221246..221254,221291..221296,221390..221392,
                     221498..221500,221504..221509,221582..221587)
                     /locus_tag="COSY_0221"
                     /note="active site"
                     /db_xref="CDD:238285"
     misc_feature    order(221159..221167,221267..221272,221279..221281,
                     221288..221290,221297..221299)
                     /locus_tag="COSY_0221"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238285"
     gene            221632..222750
                     /gene="hemN"
                     /locus_tag="COSY_0222"
                     /db_xref="GeneID:5171923"
     CDS             221632..222750
                     /gene="hemN"
                     /locus_tag="COSY_0222"
                     /EC_number="1.3.99.22"
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="YP_001219076.1"
                     /db_xref="GI:148244382"
                     /db_xref="GeneID:5171923"
                     /translation="MSYTLELPPLSLYIHYPWCVKKCPYCDFNSHDCNQRSGYIESLL
                     EDLNEDLDYIQGRAIQSIFLGGGTPSLMSEQELFKLFTGLKKRLKFVNDIEITLETNP
                     GIFEIEKFKLFKHIGINRLSIGVQSFNDRHLQSLGRIHNADEAIYACKQANQVGFKYF
                     NIDIMYGLERQTLDECLSDVRQAMNLKPDHISFYQLTIEPNTYFAKYTPILPSDEVVW
                     QMGDAGVSLLERNGYTRYEVSAFGKTPSKHNLNYWQFGDYVGIGAGAHGKITLLKESF
                     PFRTIKARLPKDYLKNRQKQVNQIKNLNFDFMLNALRLKHGFNLRLFELRTRQPIQVI
                     ECQLNKAKALGLFELDGKLAKPSKKGFDFLNDLQAIFL"
     misc_feature    221647..222747
                     /gene="hemN"
                     /locus_tag="COSY_0222"
                     /note="coproporphyrinogen III oxidase; Provisional;
                     Region: PRK08898"
                     /db_xref="CDD:236346"
     misc_feature    221677..222279
                     /gene="hemN"
                     /locus_tag="COSY_0222"
                     /note="Radical SAM superfamily. Enzymes of this family
                     generate radicals by combining a 4Fe-4S cluster and
                     S-adenosylmethionine (SAM) in close proximity. They are
                     characterized by a conserved CxxxCxxC motif, which
                     coordinates the conserved iron-sulfur cluster; Region:
                     Radical_SAM; cd01335"
                     /db_xref="CDD:100105"
     misc_feature    order(221686..221688,221692..221694,221698..221700,
                     221704..221712,221824..221826,221830..221835,
                     221926..221934,222001..222003,222124..222126,
                     222214..222219)
                     /gene="hemN"
                     /locus_tag="COSY_0222"
                     /note="FeS/SAM binding site; other site"
                     /db_xref="CDD:100105"
     gene            223648..224577
                     /gene="argB"
                     /locus_tag="COSY_0223"
                     /db_xref="GeneID:5172673"
     CDS             223648..224577
                     /gene="argB"
                     /locus_tag="COSY_0223"
                     /EC_number="2.7.2.8"
                     /note="catalyzes the phosphorylation of
                     N-acetyl-L-glutamate to form N-acetyl-L-glutamate
                     5-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="YP_001219077.1"
                     /db_xref="GI:148244383"
                     /db_xref="GeneID:5172673"
                     /translation="MLHNMSNNIHNIASVLTESLSYFQKFQGKTIVIKYGGNAMVDEA
                     LKSSFARDIVLMKSVGMNPIVVHGGGPQIGKILEKIGKQSQFIDGMRVTDSETMDVVE
                     MVLGGLVNKEIVNLIHQHGGHSIGLTGKDGSLISAKKLKSDIKPELTSEIIDLGHVGE
                     VDKIDISVINLLLKGDFIPVIAPIGVGKDGFSYNINADLVAGSIAQALNAEKLILLTN
                     TSGLLDANGELLTGLDVNIIDSLIENGTIYGGMLPKIDCALSSVRNGVKSTHIIDGRV
                     AHAVLLEIFTDNGVGTLITCNESGTLITYNEQG"
     misc_feature    223690..224529
                     /gene="argB"
                     /locus_tag="COSY_0223"
                     /note="AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic
                     (NAGK-C) catalyzes the phosphorylation of the gamma-COOH
                     group of N-acetyl-L-glutamate (NAG) by ATP in the second
                     step of arginine biosynthesis found in some bacteria and
                     photosynthetic organisms using the...; Region: AAK_NAGK-C;
                     cd04250"
                     /db_xref="CDD:239783"
     misc_feature    223690..223719
                     /gene="argB"
                     /locus_tag="COSY_0223"
                     /note="feedback inhibition sensing region; other site"
                     /db_xref="CDD:239783"
     misc_feature    order(223693..223701,223705..223707,223714..223719,
                     223798..223800,223810..223812,223822..223824,
                     223882..223887,223942..223944,223951..223956,
                     223969..223971,223978..223980,223990..223992,
                     224011..224013,224017..224025,224029..224031,
                     224035..224046,224149..224151,224176..224178,
                     224479..224481,224488..224493,224503..224505)
                     /gene="argB"
                     /locus_tag="COSY_0223"
                     /note="homohexameric interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239783"
     misc_feature    order(223747..223749,223756..223761,224233..224235,
                     224296..224304,224314..224316,224383..224385,
                     224389..224391,224395..224400,224407..224409)
                     /gene="argB"
                     /locus_tag="COSY_0223"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239783"
     misc_feature    order(223849..223854,223915..223920,224227..224229,
                     224233..224238)
                     /gene="argB"
                     /locus_tag="COSY_0223"
                     /note="N-acetyl-L-glutamate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239783"
     gene            224564..225421
                     /gene="pyrK"
                     /locus_tag="COSY_0224"
                     /db_xref="GeneID:5172132"
     CDS             224564..225421
                     /gene="pyrK"
                     /locus_tag="COSY_0224"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="YP_001219078.1"
                     /db_xref="GI:148244384"
                     /db_xref="GeneID:5172132"
                     /translation="MNKASRNQIKVCDCQILAHSRFENEQYILTLSSSVIAQQSKPGQ
                     FVHLRVSDFLAMRRPISIMLVDSEKGTFDLLYKVVGKGTRQLAKQKVGDVLSIIGPIG
                     NSFELTNKKRPLLIGGGVGMPPMIAIAQQIKNSDYKSFAILGSEVPFPFSAKLANNGK
                     DYQGATHTMTELEDWGIECRLASFQGFDGVFKGFVTDLAKVYLDSLTVDEIMQVEVYA
                     CGPHSMLVTVASLIKEYDLPCQVSLEENMACAVGGCAGCVVEVQTEQGISMQRICVDG
                     PVFDAYQVF"
     misc_feature    224609..225403
                     /gene="pyrK"
                     /locus_tag="COSY_0224"
                     /note="FAD/NAD binding domain in the electron transfer
                     subunit of dihydroorotate dehydrogenase. Dihydroorotate
                     dehydrogenases (DHODs) catalyze the only redox reaction in
                     pyrimidine de novo biosynthesis. They catalyze the
                     oxidation of (S)-dihydroorotate to...; Region:
                     DHOD_e_trans; cd06218"
                     /db_xref="CDD:99814"
     misc_feature    224642..225418
                     /gene="pyrK"
                     /locus_tag="COSY_0224"
                     /note="dihydroorotate dehydrogenase electron transfer
                     subunit; Reviewed; Region: PRK00054"
                     /db_xref="CDD:234601"
     misc_feature    order(224729..224731,224735..224746,224786..224794,
                     224810..224818,224921..224923,225296..225301)
                     /gene="pyrK"
                     /locus_tag="COSY_0224"
                     /note="FAD binding pocket [chemical binding]; other site"
                     /db_xref="CDD:99814"
     misc_feature    order(224735..224737,224741..224746)
                     /gene="pyrK"
                     /locus_tag="COSY_0224"
                     /note="FAD binding motif [chemical binding]; other site"
                     /db_xref="CDD:99814"
     misc_feature    order(224807..224809,224816..224818,224825..224827,
                     224837..224839,224861..224863,224867..224869)
                     /gene="pyrK"
                     /locus_tag="COSY_0224"
                     /note="phosphate binding motif [ion binding]; other site"
                     /db_xref="CDD:99814"
     misc_feature    order(224906..224908,224918..224929,224933..224935)
                     /gene="pyrK"
                     /locus_tag="COSY_0224"
                     /note="beta-alpha-beta structure motif; other site"
                     /db_xref="CDD:99814"
     misc_feature    order(224921..224926,224993..225001,225221..225226)
                     /gene="pyrK"
                     /locus_tag="COSY_0224"
                     /note="NAD binding pocket [chemical binding]; other site"
                     /db_xref="CDD:99814"
     misc_feature    order(225308..225310,225323..225325,225332..225334,
                     225380..225382)
                     /gene="pyrK"
                     /locus_tag="COSY_0224"
                     /note="Iron coordination center [ion binding]; other site"
                     /db_xref="CDD:99814"
     gene            225418..226056
                     /locus_tag="COSY_0225"
                     /db_xref="GeneID:5171958"
     CDS             225418..226056
                     /locus_tag="COSY_0225"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219079.1"
                     /db_xref="GI:148244385"
                     /db_xref="GeneID:5171958"
                     /translation="MIKDNLIKVQLRISQVNHTQSVTLVAVSKTRSVYELQQAIDVGQ
                     QHFAENYLQEALIKINHLKGQNLIWHFIGPIQSNKTLKIAKNFDWVHSIGRLKIAQRL
                     NDQRPKNLPKLKVLLQINIDNEPTKSGVLVGQIDELITHFESLKNLTLRGFMCVPNPF
                     SSAQSFSRMENIIKQYSNLDVLSMGMSHDLELAIENGATSVRIGADIFGKRT"
     misc_feature    225418..226047
                     /locus_tag="COSY_0225"
                     /note="Pyridoxal 5-phosphate (PLP)-binding TIM barrel
                     domain of Type III PLP-Dependent Enzymes, Yggs-like
                     proteins; Region: PLPDE_III_Yggs_like; cd06824"
                     /db_xref="CDD:143497"
     misc_feature    order(225496..225498,225502..225504,225565..225567,
                     225631..225633,225883..225885,225973..225975,
                     226021..226023,226027..226032)
                     /locus_tag="COSY_0225"
                     /note="pyridoxal 5'-phosphate (PLP) binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:143497"
     misc_feature    225502..225504
                     /locus_tag="COSY_0225"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:143497"
     gene            226236..226721
                     /locus_tag="COSY_0226"
                     /db_xref="GeneID:5172020"
     CDS             226236..226721
                     /locus_tag="COSY_0226"
                     /EC_number="3.5.1.1"
                     /note="Similar to the N-terminal region of periplasmic
                     L-asparaginase II AnsB (348 aa) in Escherichia coli.
                     archaeal Glu-tRNAGln amidotransferase."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase"
                     /protein_id="YP_001219080.1"
                     /db_xref="GI:148244386"
                     /db_xref="GeneID:5172020"
                     /translation="MRIKLLITGGTIDKVYDELIGQLVFQRTYLIDMLNRSRSMVDTL
                     SEVLFLKDSLDMSDIDRALIVKKCQESDTSHILITHGTDSMIRTAKLLAKEINNKTIV
                     LFGSMIPYSINCSDALFNLGVALSAVQIKEYGVYITMNGQVFDFDKVEKNKEIGIFTL
                     L"
     misc_feature    226239..>226667
                     /locus_tag="COSY_0226"
                     /note="Bacterial L-asparaginases and related enzymes;
                     Region: L-asparaginase_like; cl00216"
                     /db_xref="CDD:241694"
     misc_feature    order(226263..226268,226392..226397,226476..226484,
                     226551..226553)
                     /locus_tag="COSY_0226"
                     /note="active site"
                     /db_xref="CDD:199205"
     gene            227077..229551
                     /locus_tag="COSY_0227"
                     /db_xref="GeneID:5172032"
     CDS             227077..229551
                     /locus_tag="COSY_0227"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219081.1"
                     /db_xref="GI:148244387"
                     /db_xref="GeneID:5172032"
                     /translation="MMIKRTLLGGTKVLKISTWVSVIFSLIIVLIVVLFVTFPILLKA
                     PIENQLSSLTGLDVRLSKITFYFENIGIALQVHDIAILSNKNQQKVAIIKKLSWHVNL
                     LNLFDNIYHSSKIYIDTLMLFSNSGNVNINNINNIVSLDMLEKLYFFESLHVNKIIIK
                     HAIKITPLTLKRDGVQFLLTIPRQDLVTKYFNVTFSLSNVQVSRDGCLTLPITVINND
                     FKLVLGLKLYNQKNDDFIQITGLIKRMNVVKISDYLPVVLIGSATYQWIKQAFQSGTI
                     DNINIDIKKNLSKELPAKIKINAHLTNTELLFNADWHNLKQLDANIYIDDKQITVTVN
                     HTMLNEMFLQDIKVQMLDMSKDKLEVSVVGKINSYSEVLTRFLKEVPLDSNLNNILNY
                     FSLSGKVIADVELTIPLNKTDLTLDIDLNIEDNHLTILGGAIVIKNYNAHLVLHNNQI
                     ISYGMGNIRGKSFNIHINSNNQDSGLDVLFAVVLTNSSDNFEFHLAKYLNQSWQVNIK
                     SDALKTDAKIILNDGVLPEVKLTNLQVTGLDKIKGNWDIRVNDIPSMHLSVQDIQIGE
                     KKLPNFHATLESQDKMLKIINLEFSGVGFGAQNLSFNGVWINGRTKLFAKVKGNKLSE
                     FLDKLNIKEKVRGGQFEFDVRLFCNCAPWNMSSEDISGLIKVKVKEGVFTNEDPNIGL
                     VLSLLNIKSIAKRLELNITDLISKGFAYDTIDAQIYINNSMATIVHFELNSSSSIITL
                     TGSSKFVEQTYHLEAKVLPAISDAVPIATYLAGGGLAGLGVWLTDKMLFKGELINNIV
                     DKVVEFKYKITGPWNKPVIEKISTVL"
     misc_feature    227809..228645
                     /locus_tag="COSY_0227"
                     /note="Protein of unknown function; Region: DUF3971;
                     pfam13116"
                     /db_xref="CDD:221927"
     misc_feature    228787..229524
                     /locus_tag="COSY_0227"
                     /note="AsmA-like C-terminal region; Region: AsmA_2;
                     pfam13502"
                     /db_xref="CDD:222180"
     gene            229548..230975
                     /gene="tldD"
                     /locus_tag="COSY_0228"
                     /db_xref="GeneID:5172208"
     CDS             229548..230975
                     /gene="tldD"
                     /locus_tag="COSY_0228"
                     /note="TldD protein suppresses the inhibitory activity of
                     the carbon storage regulator (CsrA)."
                     /codon_start=1
                     /transl_table=11
                     /product="PmbA/TldD family DNA gyrase modulator"
                     /protein_id="YP_001219082.1"
                     /db_xref="GI:148244388"
                     /db_xref="GeneID:5172208"
                     /translation="MIEQLLDDHHLNQEIITTLLSSLAVKGTDYADLYFQHSAVESWF
                     LEESIVKSGTYHISHGVGARAVSFDQTGFAYSDDLNLRSIEKAINFAKGVSMYQTAVG
                     KIQDFQPIPQVAKYSGLNPLNSFSSQEKVDFLNRIDKIARKESKVTQVSASISGGFSE
                     VLITSTDGVFAKDYRPMVRVSVNVIVECNGRIESASSGGGGRYDYQYFVNHALDEIYV
                     NEAIRQALLALESKNAPAGSMPVILGSGWPGVLLHEAIGHGLEGDFNRKKSSVFTNRI
                     GEQVASDKCTIVDNGTLANRRGSLTIDDEGTPTQNTLLIENGILKGYLFDKINAKLMD
                     TVSTGNGRRESYAHIPMPRMTNTYMLNGQDSLDDMIASVDYGIYAINFDGGQVDITSG
                     KFVFSANEAYLIKNGKIMHPVKGVTLIGSGDKVLKKISMVANDLKLDNGVGICGKDGQ
                     NVPVGVGQPSLKIDQLTVGGTEVNV"
     misc_feature    229554..230960
                     /gene="tldD"
                     /locus_tag="COSY_0228"
                     /note="protease TldD; Provisional; Region: tldD; PRK10735"
                     /db_xref="CDD:182685"
     gene            231072..231428
                     /gene="nuoA"
                     /locus_tag="COSY_0229"
                     /db_xref="GeneID:5172011"
     CDS             231072..231428
                     /gene="nuoA"
                     /locus_tag="COSY_0229"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain A"
                     /protein_id="YP_001219083.1"
                     /db_xref="GI:148244389"
                     /db_xref="GeneID:5172011"
                     /translation="MLENYLPIVVFIFLGLFFGIGPMLIGYLLGPSKPNEEKNTQFEC
                     GFPAFNDSRTYFNIRYYLVAILFILFDLEVAFVFPWAVVQSQLGWFGFVVMSIFLFLL
                     IVGFVFEWKNGALEWE"
     misc_feature    <231150..231425
                     /gene="nuoA"
                     /locus_tag="COSY_0229"
                     /note="NADH-ubiquinone/plastoquinone oxidoreductase, chain
                     3; Region: Oxidored_q4; cl00535"
                     /db_xref="CDD:241931"
     gene            231432..231911
                     /gene="nuoB"
                     /locus_tag="COSY_0230"
                     /db_xref="GeneID:5171955"
     CDS             231432..231911
                     /gene="nuoB"
                     /locus_tag="COSY_0230"
                     /EC_number="1.6.5.3"
                     /note="The point of entry for the majority of electrons
                     that traverse the respiratory chain eventually resulting
                     in the reduction of oxygen"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase subunit B"
                     /protein_id="YP_001219084.1"
                     /db_xref="GI:148244390"
                     /db_xref="GeneID:5171955"
                     /translation="MAIEGLIKQGFVTMSLDRVINWARTGSLWPMTFGLACCAVEMME
                     AGSSRYDLDRFGIVFRPTPRQSDLMIVAGTLTNKMAPALRKVYDQMPEPKWVISMGSC
                     ANGGGYYHYSYAVIRGCDRIVPVDIYVPGCPPTAEALLYGIMQLQDKIRRTNTIART"
     misc_feature    231432..231887
                     /gene="nuoB"
                     /locus_tag="COSY_0230"
                     /note="NADH dehydrogenase subunit B; Validated; Region:
                     PRK06411"
                     /db_xref="CDD:235797"
     gene            231911..232525
                     /gene="nuoC"
                     /locus_tag="COSY_0231"
                     /db_xref="GeneID:5171948"
     CDS             231911..232525
                     /gene="nuoC"
                     /locus_tag="COSY_0231"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain C"
                     /protein_id="YP_001219085.1"
                     /db_xref="GI:148244391"
                     /db_xref="GeneID:5171948"
                     /translation="MQDLKTSLVEVFGKTNLVESFDELTLTVGSQNIIKTCLKLRDFF
                     SFDTLIDLCGVDYLTYGQSDWNGNASASGFSRGRSHQGLKDIHEERFAVVYHLLSVSK
                     NKRIRVKSFVDEVEPIIKSVTDIWASADWYEREAFDLMGILFENHTDLRRILTDYGFT
                     GHPLRKDFPMIGEVEMRYDEDLCRVIYEKVSIEPNVNVPRVIRK"
     misc_feature    231914..232519
                     /gene="nuoC"
                     /locus_tag="COSY_0231"
                     /note="NADH dehydrogenase subunit C; Provisional; Region:
                     PRK06074"
                     /db_xref="CDD:235691"
     misc_feature    231980..232426
                     /gene="nuoC"
                     /locus_tag="COSY_0231"
                     /note="Respiratory-chain NADH dehydrogenase, 30 Kd
                     subunit; Region: Complex1_30kDa; cl16917"
                     /db_xref="CDD:247642"
     gene            232527..233780
                     /gene="nuoD"
                     /locus_tag="COSY_0232"
                     /db_xref="GeneID:5171947"
     CDS             232527..233780
                     /gene="nuoD"
                     /locus_tag="COSY_0232"
                     /EC_number="1.6.5.3"
                     /note="Catalyzes the transfer of electrons from NADH to
                     quinone"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase subunit D"
                     /protein_id="YP_001219086.1"
                     /db_xref="GI:148244392"
                     /db_xref="GeneID:5171947"
                     /translation="MSEIRNYTLNFGPQHPAAHGVLRLILEIDGEVIERADPHIGLLH
                     RGTEKLVESKPYNQSIGYMDRLDYVSMMCNEHAYVMAIEAMLNLKVPKRAQYIRVMFD
                     EITRILNHLMWLGTHGLDVGAMSIFLYAFREREKLIDCYEAVSGSRMHATYYRPGGVY
                     RDLPDKMPQYLASDFRTSKELETMNENRQGSLLDFIADFVKEFPKSIKQYDDLLTDNR
                     IWKQRLVNIGVVSANRAKQLGFTGPMLRGSGVEWDLRKNQPYAVYDQLKFDIPVGMTG
                     DSYDRYLVRMEEMRQSNYIIKQCVKWLRENPGAVMSDDHKVSQPKRTNMKNDMESLIH
                     HFKLFTEGYCLPEGEVYRAVEHPKGEFGVYLISDGANKPYRVKIRAPGFSHLAAMNEM
                     TRGHMLSDVVTIIGTQDVVFGEIDR"
     misc_feature    232527..233777
                     /gene="nuoD"
                     /locus_tag="COSY_0232"
                     /note="NADH dehydrogenase subunit D; Validated; Region:
                     PRK06075"
                     /db_xref="CDD:180385"
     misc_feature    232533..233777
                     /gene="nuoD"
                     /locus_tag="COSY_0232"
                     /note="NADH:ubiquinone oxidoreductase 49 kD subunit 7
                     [Energy production and conversion]; Region: NuoD; COG0649"
                     /db_xref="CDD:223722"
     gene            233777..234250
                     /gene="nuoE"
                     /locus_tag="COSY_0233"
                     /db_xref="GeneID:5171944"
     CDS             233777..234250
                     /gene="nuoE"
                     /locus_tag="COSY_0233"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain E"
                     /protein_id="YP_001219087.1"
                     /db_xref="GI:148244393"
                     /db_xref="GeneID:5171944"
                     /translation="MISIRAKNQIDVWIAKYPKDRQSSAVMQALKIVQAENKNILSAS
                     IIQEVADYLDMPDIVVQEVATFYENYNYKKVGKYVIRFCHNISCMLNGADDLIKHLEN
                     KLGVKTGEVTLDGLISVKKVECLGACVGAPMFQINEKYFENLTIDKIDKIVDNLK"
     misc_feature    233777..234247
                     /gene="nuoE"
                     /locus_tag="COSY_0233"
                     /note="NADH dehydrogenase subunit E; Validated; Region:
                     PRK07539"
                     /db_xref="CDD:181024"
     misc_feature    234005..234244
                     /gene="nuoE"
                     /locus_tag="COSY_0233"
                     /note="TRX-like [2Fe-2S] Ferredoxin (Fd) family,
                     NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily;
                     Nuo, also called respiratory chain Complex 1, is the entry
                     point for electrons into the respiratory chains of
                     bacteria and the mitochondria of eukaryotes; Region:
                     TRX_Fd_NuoE; cd03064"
                     /db_xref="CDD:239362"
     misc_feature    order(234011..234013,234017..234019,234137..234145)
                     /gene="nuoE"
                     /locus_tag="COSY_0233"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239362"
     misc_feature    order(234023..234025,234038..234040,234146..234148,
                     234158..234160)
                     /gene="nuoE"
                     /locus_tag="COSY_0233"
                     /note="[2Fe-2S] cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239362"
     gene            234247..235515
                     /gene="nuoF"
                     /locus_tag="COSY_0234"
                     /db_xref="GeneID:5171939"
     CDS             234247..235515
                     /gene="nuoF"
                     /locus_tag="COSY_0234"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain F"
                     /protein_id="YP_001219088.1"
                     /db_xref="GI:148244394"
                     /db_xref="GeneID:5171939"
                     /translation="MNEVCFKNLKKDQCWSLKIYEASGGYSSWRKILKGELTPEQIID
                     ELKLSGLRGRGGAGFPTGLKWSFMPRHSDGQKYVVCNSDEGEPGTCKDRDILRFNPHA
                     VIEGMAIGGFVMNASVGYNYIRGEFMEPFKRFESALEEAYKAGLLGQNINNSSINFDL
                     YTHLGAGAYICGEETALLESIEGKKGQPRFKPPFPANVGLFGKPTTINNTESFASVPE
                     ILRCGGQWFADIGVENSGGCKLFSVSGHVTNPANFEVPMGISFKDLLEMAGGMRDGAK
                     LKAVIPGGSSTPVLTAEIVMNMTMDYDGIEKAGSMLGAGSVIVMNESTCMVEVLTRLA
                     HFYYDESCGQCTPCREGTGWLYRVLKRIIDGNGRQGDIDLLLSVQNKIMGNTICALGD
                     AAAMPVESFLRNFREEFEYYIKYRKSMVKG"
     misc_feature    234262..235488
                     /gene="nuoF"
                     /locus_tag="COSY_0234"
                     /note="NADH:ubiquinone oxidoreductase, NADH-binding (51
                     kD) subunit [Energy production and conversion]; Region:
                     NuoF; COG1894"
                     /db_xref="CDD:224806"
     misc_feature    234964..235116
                     /gene="nuoF"
                     /locus_tag="COSY_0234"
                     /note="SLBB domain; Region: SLBB; pfam10531"
                     /db_xref="CDD:220798"
     misc_feature    235225..235362
                     /gene="nuoF"
                     /locus_tag="COSY_0234"
                     /note="NADH-ubiquinone oxidoreductase-F iron-sulfur
                     binding region; Region: NADH_4Fe-4S; smart00928"
                     /db_xref="CDD:197996"
     gene            235520..237781
                     /gene="nuoG"
                     /locus_tag="COSY_0235"
                     /db_xref="GeneID:5171937"
     CDS             235520..237781
                     /gene="nuoG"
                     /locus_tag="COSY_0235"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain G"
                     /protein_id="YP_001219089.1"
                     /db_xref="GI:148244395"
                     /db_xref="GeneID:5171937"
                     /translation="MTDIEININGNIVSAKAGEMLIVVTDRENISVPRFCYHKKLSVV
                     SSCRICLVDVEGVLKPQPACSTPVIQGMKVQTQNVKTKNSQKSVMEFLLINHPLDCPI
                     CDQGGECELQDMAVEYGSDISSFSEGKRIVTDSDIGVLIQTDMTRCIHCTRCVRFGVE
                     IAGIMEMGGTGRGEHLKIEPFLEQGIQSELSGNMIDICPVGALTSKPFKYELRSWQMN
                     SIPSIARHDLVGSNLFVQTYKGKVKRVVSADNDLVNEIWISDRDRFSYESLTHENRLL
                     KPQIKVQGRWNQVSWEVALDYAVKGLNSHILNHQKADQLGGLVSNTATMEEFYLFKKI
                     LTEVGCDNIDYRLNVKNLDNTIILDSNIKLDALEKIDYALIIGTNIRLEQPMINHRLR
                     KATKKGADIDVLNVMVFDFNYSLHTENIIAPNKIAFTLAGVLKSIMIDNGQELPDYLI
                     VIDVSEVAKNIAYKVLNSDSSVIILGEHIINNEDASTIANLVTKIAQSTNSRTLNLSI
                     TANTLAANLVGCVPQNSGMNVNTMFVSDMRGFILLDIYPQYNFHHLGSAIKAFEKDNT
                     FVISLNSFKDDIVAGYSDVILPIASIYETSGTHLNINNDMQSYTAAVKAPNEVKPAWK
                     VLKVMADLLELPGFNYDDSTQVLAEISYQSQVIHTRDIKDNLASHHNGISIIWQNSSY
                     SIDAVLRHSGTLQKTKIGQINNAYMNQTSAKTLKVSVGDKYLGVVVVITDAVADDCVF
                     INTNQTANIQGQA"
     misc_feature    235529..237682
                     /gene="nuoG"
                     /locus_tag="COSY_0235"
                     /note="NADH dehydrogenase subunit G; Validated; Region:
                     PRK09129"
                     /db_xref="CDD:236386"
     misc_feature    235529..235753
                     /gene="nuoG"
                     /locus_tag="COSY_0235"
                     /note="2Fe-2S iron-sulfur cluster binding domain; Region:
                     Fer2_4; pfam13510"
                     /db_xref="CDD:205688"
     misc_feature    235772..235894
                     /gene="nuoG"
                     /locus_tag="COSY_0235"
                     /note="NADH-ubiquinone oxidoreductase-G iron-sulfur
                     binding region; Region: NADH-G_4Fe-4S_3; pfam10588"
                     /db_xref="CDD:204520"
     misc_feature    236180..237418
                     /gene="nuoG"
                     /locus_tag="COSY_0235"
                     /note="Molybdopterin-Binding (MopB) domain of the MopB
                     superfamily of proteins, a  large, diverse, heterogeneous
                     superfamily of enzymes that, in general, bind
                     molybdopterin as a cofactor. The MopB domain is found in a
                     wide variety of molybdenum- and...; Region:
                     Molybdopterin-Binding; cl09928"
                     /db_xref="CDD:245203"
     misc_feature    order(236300..236302,236558..236560,236645..236650,
                     236654..236656,236663..236668,236729..236737,
                     236798..236800,237038..237040,237152..237160,
                     237230..237238,237248..237250,237284..237289,
                     237302..237304)
                     /gene="nuoG"
                     /locus_tag="COSY_0235"
                     /note="molybdopterin cofactor binding site; other site"
                     /db_xref="CDD:238218"
     gene            237781..238854
                     /gene="nuoH"
                     /locus_tag="COSY_0236"
                     /db_xref="GeneID:5171933"
     CDS             237781..238854
                     /gene="nuoH"
                     /locus_tag="COSY_0236"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain H"
                     /protein_id="YP_001219090.1"
                     /db_xref="GI:148244396"
                     /db_xref="GeneID:5171933"
                     /translation="MELWQTFVKMVHALVPWLDGTVAIILIIFIKAIALLIPLMLVVA
                     YFTYAERKVIGYMQLRIGPNRVGPKGWLQPIADALKLMTKEIIFPTKANIYLFLLAPV
                     LAIAPAIAVWAVIPFDESIYITNLDISLLYVLAIGSIGVYGIILAGWASNSKYPLLGA
                     LRSAALLVSYEIVIGFALVTVVMIAGSVNLNTIVQAQQGGIIYWYFIPLFPIMIIFFI
                     SSLVETNRAPFDVVEGESEIVGGTHVEYSGMTFAVFFLAEYANMILMAVLSVIMFFGG
                     WHSPFEAIPYLESVFSWIPGMIWLLAKTTFFMFLYLWVRATFPRFRYDQIMHLSWKVF
                     LPITIIWIFVVALMTQLQLSPWF"
     misc_feature    237892..238824
                     /gene="nuoH"
                     /locus_tag="COSY_0236"
                     /note="NADH:ubiquinone oxidoreductase subunit H;
                     Provisional; Region: PRK06076"
                     /db_xref="CDD:235692"
     misc_feature    237895..238818
                     /gene="nuoH"
                     /locus_tag="COSY_0236"
                     /note="Formate hydrogenlyase subunit 4 [Energy production
                     and conversion]; Region: HyfC; COG0650"
                     /db_xref="CDD:223723"
     gene            238868..239359
                     /gene="nuoI"
                     /locus_tag="COSY_0237"
                     /db_xref="GeneID:5171931"
     CDS             238868..239359
                     /gene="nuoI"
                     /locus_tag="COSY_0237"
                     /EC_number="1.6.5.3"
                     /note="Catalyzes the transfer of electrons from NADH to
                     quinone"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase subunit I"
                     /protein_id="YP_001219091.1"
                     /db_xref="GI:148244397"
                     /db_xref="GeneID:5171931"
                     /translation="MIKKLNKLIKNFTLNELRTGLKVTAKELVNKKITVQFPEERTPI
                     SPRFRGLHALRRYPNGEERCIACKLCEAVCPANAITIESKMRDDGTRRTTQYDIDLFK
                     CIFCGFCEEACPVDAIVETQIFDYVFESRQGSIMTKERLLEVGSQNEQVINQTKFEDA
                     KYK"
     misc_feature    238886..239356
                     /gene="nuoI"
                     /locus_tag="COSY_0237"
                     /note="NADH dehydrogenase subunit I; Provisional; Region:
                     PRK05888"
                     /db_xref="CDD:235637"
     misc_feature    239048..239107
                     /gene="nuoI"
                     /locus_tag="COSY_0237"
                     /note="4Fe-4S binding domain; Region: Fer4; pfam00037"
                     /db_xref="CDD:215671"
     misc_feature    239153..239221
                     /gene="nuoI"
                     /locus_tag="COSY_0237"
                     /note="4Fe-4S binding domain; Region: Fer4; pfam00037"
                     /db_xref="CDD:215671"
     gene            239369..239980
                     /gene="nuoJ"
                     /locus_tag="COSY_0238"
                     /db_xref="GeneID:5171928"
     CDS             239369..239980
                     /gene="nuoJ"
                     /locus_tag="COSY_0238"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain J"
                     /protein_id="YP_001219092.1"
                     /db_xref="GI:148244398"
                     /db_xref="GeneID:5171928"
                     /translation="MGFEQIIFYIFSFWFVVSSLAMIFSRNAAKAVLFLVLAFFSAAS
                     IWILLEAEFLAIILILVYVGAVMVLFLFVIKMLNIDKSTIKARFTGYLPLRLIVAIII
                     IIEMSLVLGSNQFGLDVFSVPERHSEDYSNITVLAMQIYTTYVYPFELAAVLLLIAII
                     AAITLVHRNDTSRKKQSISEQVNVQAKDRVRLVSIILPDKKEK"
     misc_feature    239369..239956
                     /gene="nuoJ"
                     /locus_tag="COSY_0238"
                     /note="NADH:ubiquinone oxidoreductase subunit J;
                     Provisional; Region: PRK06638"
                     /db_xref="CDD:235844"
     gene            239981..240286
                     /gene="nuoK"
                     /locus_tag="COSY_0239"
                     /db_xref="GeneID:5171924"
     CDS             239981..240286
                     /gene="nuoK"
                     /locus_tag="COSY_0239"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain K"
                     /protein_id="YP_001219093.1"
                     /db_xref="GI:148244399"
                     /db_xref="GeneID:5171924"
                     /translation="MVSLSEYLILSSTIFCIGLVGIFVNRTNIITLLMCVELILVAVN
                     TNFVAFSHFLGDEAGQIFVFFILTVAASEVAIGLAILTLLFRGSGSISVDVTNNLKG"
     misc_feature    239981..240283
                     /gene="nuoK"
                     /locus_tag="COSY_0239"
                     /note="NADH:ubiquinone oxidoreductase subunit K;
                     Validated; Region: PRK05715"
                     /db_xref="CDD:180218"
     gene            240289..242250
                     /gene="nuoL"
                     /locus_tag="COSY_0240"
                     /db_xref="GeneID:5171921"
     CDS             240289..242250
                     /gene="nuoL"
                     /locus_tag="COSY_0240"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain L"
                     /protein_id="YP_001219094.1"
                     /db_xref="GI:148244400"
                     /db_xref="GeneID:5171921"
                     /translation="MEKIYLTIALSPLVGAVIAGFFGTMLGKTATHTLTILGLLISTV
                     LSLYVFNYHILDRGEVFNQNLYTWIQINNLNISVGFLIDNLTAVMLVVVSFISLMVHI
                     YTIGYMYNDAGYTKFFSYISLFTFSMFILIMSNNFMQLFFGWEAVGLVSYLLIGFWHH
                     KERAVQANLKAFLVNRVGDFGFLLGISLILVFSGSLDYAEVFLSLEKTIGQQLWGLDL
                     ITVICLLLFVGAMGKSAQVPLHVWLPGSMEGPTPISALIHAATMVTAGIFMVSRMSPM
                     FELSDIALTVVMVVGAITALFMGLLGIVQNDIKKVVAYSTLSQLGYMTVALGVSAYSV
                     AIFHLMTHAFFKALLFLVAGSVIVAMHHQQDIRKMGGLRKKMPITYWTALIGTLALVG
                     FPGFSGFYSKDMIIEAVYFSSLSYSSWVYVAVVVGVFITSFYSLRMFFLVFHGESRID
                     VHTVTHLHESASSIIFPLIVLAIPSLMIGYLTIEFMLFNGWLDNAITVASSHISMAKL
                     KYEFHSAASMIPHAIQTLPFWMMIGGIATAWLFSIYKVQWADWVQKKYYRTNYVLESL
                     YGFDRFNDLIFVSGVKKLGNFLYKVSDISLIDKLLVNGSAKLIVLVGKILRLIQTGYV
                     YHYAFLMIFSLLIILTWVLFTGENPLIEL"
     misc_feature    240289..242226
                     /gene="nuoL"
                     /locus_tag="COSY_0240"
                     /note="NADH:ubiquinone oxidoreductase subunit L; Reviewed;
                     Region: PRK06590"
                     /db_xref="CDD:235836"
     misc_feature    240472..240657
                     /gene="nuoL"
                     /locus_tag="COSY_0240"
                     /note="NADH-Ubiquinone oxidoreductase (complex I), chain 5
                     N-terminus; Region: Oxidored_q1_N; pfam00662"
                     /db_xref="CDD:109709"
     misc_feature    240688..241512
                     /gene="nuoL"
                     /locus_tag="COSY_0240"
                     /note="NADH-Ubiquinone/plastoquinone (complex I), various
                     chains; Region: Oxidored_q1; pfam00361"
                     /db_xref="CDD:201180"
     gene            242253..243758
                     /gene="nuoM"
                     /locus_tag="COSY_0241"
                     /db_xref="GeneID:5171920"
     CDS             242253..243758
                     /gene="nuoM"
                     /locus_tag="COSY_0241"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain M"
                     /protein_id="YP_001219095.1"
                     /db_xref="GI:148244401"
                     /db_xref="GeneID:5171920"
                     /translation="MGISLLSLLIWLPIFSGVLVIFIGNGRANIARWVSLILSIFIFV
                     ISLSLYTSFDSSTHLMQFVEKSSWISQFNINYHIGVDGISVPLIILTTFSTILVIIAG
                     WEVVIKRCSHYMAAFLMMEGLIIGVFSSLDAILFYVFWEASLIPMLLIIGIWGGVNRV
                     YASIKFFLYTFLGSVFMLLSLIYMYNKGGSFSIIDMHNLKLSFTEQSYIFWAFFMAFA
                     VKVPMFPMHTWLPDAHVQAPTGGSVILAAIMLKMGGYGFFRFSLPIIPDASLEFSEIM
                     IILSLIAIVYIGFIALVQRDIKKLIAYSSISHMGFVTLGIFTLFLSYKQNIIEGSLLG
                     LEGAMVQMISHGFISAAMFLVVGVLYDRLHSREISTYGGVINTMPKFTGFVILFAMAN
                     VGLPGTSGFVGEFMVILGAIQANIWYGILSASTLIIGAAYTLWMVKRVFFGVITNPAV
                     SMLKDINAREFSILAILAIVVLVIGLYPQPVIELMHISIEHLLHQALTSKL"
     misc_feature    242301..243737
                     /gene="nuoM"
                     /locus_tag="COSY_0241"
                     /note="NADH:ubiquinone oxidoreductase subunit M; Reviewed;
                     Region: PRK05846"
                     /db_xref="CDD:235622"
     misc_feature    242640..243485
                     /gene="nuoM"
                     /locus_tag="COSY_0241"
                     /note="NADH-Ubiquinone/plastoquinone (complex I), various
                     chains; Region: Oxidored_q1; pfam00361"
                     /db_xref="CDD:201180"
     gene            243769..245223
                     /gene="nuoN"
                     /locus_tag="COSY_0242"
                     /db_xref="GeneID:5171918"
     CDS             243769..245223
                     /gene="nuoN"
                     /locus_tag="COSY_0242"
                     /EC_number="1.6.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I chain N"
                     /protein_id="YP_001219096.1"
                     /db_xref="GI:148244402"
                     /db_xref="GeneID:5171918"
                     /translation="MNNLIEFDTSSLWVVLPEIFLLSAIIVILLLDLFLNKYSQQVTY
                     YLTQLSLLISGLLTFNLIDHPQVIIFSGSFILDNMASVFKVFMMIATMIAMVYSRHYL
                     RAHLLFRSEYFILVLLSILGMMVMVSGYSLLTLYLGLEILSLSLYALIAIAHEKVYAI
                     EAAFKYFILGAISSALLLYGMSMIYGISGSLNINEIANFVSNTDLTSRKTLIINFGLV
                     FLVIGIAFKLGSVPFHMWVPDVYQGAPTSVTLFISTVPKIAAISILIRILVNGLGSMH
                     SYWSDLFMVLSILSITLGSVVALMQTNIKRMLAYSTISHVGFIMLGFVTGTLTGYSAA
                     IFYMLVYILMSLAAFGMIILLNKQGFEVDQISDFKGLSKHSPWFALMMLIVMLSMAGI
                     PPLLGFYSKFFILQQIVSAGFITIAIFAVIFAVISTYYYLQIIKFMYFDEIDNNISIN
                     ASIDMQLVLSMNVILILVVGLFPDFLIQLVLSLF"
     misc_feature    243781..245220
                     /gene="nuoN"
                     /locus_tag="COSY_0242"
                     /note="NADH:ubiquinone oxidoreductase subunit N;
                     Provisional; Region: PRK05777"
                     /db_xref="CDD:235603"
     misc_feature    244243..244986
                     /gene="nuoN"
                     /locus_tag="COSY_0242"
                     /note="NADH-Ubiquinone/plastoquinone (complex I), various
                     chains; Region: Oxidored_q1; pfam00361"
                     /db_xref="CDD:201180"
     gene            complement(245348..246136)
                     /gene="bioC"
                     /locus_tag="COSY_0243"
                     /db_xref="GeneID:5171917"
     CDS             complement(245348..246136)
                     /gene="bioC"
                     /locus_tag="COSY_0243"
                     /note="SAM-dependent methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin biosynthesis protein BioC"
                     /protein_id="YP_001219097.1"
                     /db_xref="GI:148244403"
                     /db_xref="GeneID:5171917"
                     /translation="MSQIRLSFNKASNNYDNHALLQKEIAIRLDKKLNTISSKADIIL
                     DLGAGTGLLSKQLTKCFLNSKIICIDFSQKSLKYNPSSNKICANANYLPLLNNSIDII
                     TSNLMMQWCPDLNTLFSECFRVLKNDGLFLFSTFGPDTLKELKNSWSVVDDKIHVNTF
                     IDMHDIGDQMLQNRFQNPVMEMETWTLTYQTVIDLLHDLKAIGAQTVIKRSKSLTGKN
                     KFRLMIKMYESYKNNGKLPVTYEVIYGHAWKQTSNIANITLETQ"
     misc_feature    complement(245390..246118)
                     /gene="bioC"
                     /locus_tag="COSY_0243"
                     /note="biotin biosynthesis protein BioC; Region: BioC;
                     TIGR02072"
                     /db_xref="CDD:233708"
     misc_feature    complement(245729..246010)
                     /gene="bioC"
                     /locus_tag="COSY_0243"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(245822..245824,245870..245878,
                     245924..245929,245981..246001))
                     /gene="bioC"
                     /locus_tag="COSY_0243"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(246124..247002)
                     /locus_tag="COSY_0244"
                     /db_xref="GeneID:5172441"
     CDS             complement(246124..247002)
                     /locus_tag="COSY_0244"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="YP_001219098.1"
                     /db_xref="GI:148244404"
                     /db_xref="GeneID:5172441"
                     /translation="MIVRSLLTTLLFSANIFAEPNIVVSIKPIHSIVSSLTQGITTPK
                     LLLTTNQSAHHTHLKPSQLLLLSHADLAIFIHPNLEGGLKKILNNLSDNKKLIIGNIE
                     DIHLIHNKEYNEYELDEHQKTINYHLWLDINNMQIFAKELIEKLIKIDPNNQLNYTNN
                     LDKLNKNLNKLKQGIDQKLLFYKSKILASYSNTFDYFINANQLKKSINITNYHGERLS
                     ISKILKAKKIMKNTQTKCLLTTVEISKKRTNPLIKGLNINSVNIDIIGFNIQQKSNHY
                     FKLMHNITNKVIQCLK"
     misc_feature    complement(246127..246990)
                     /locus_tag="COSY_0244"
                     /note="ABC-type Zn2+ transport system, periplasmic
                     component/surface adhesin [Inorganic ion transport and
                     metabolism]; Region: ZnuA; COG4531"
                     /db_xref="CDD:226908"
     misc_feature    complement(246130..246954)
                     /locus_tag="COSY_0244"
                     /note="Helical backbone metal receptor (TroA-like domain).
                     These proteins have been shown to function in the ABC
                     transport of ferric siderophores and metal ions such as
                     Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site
                     is formed in the interface between...; Region: TroA-like;
                     cl00262"
                     /db_xref="CDD:241735"
     misc_feature    complement(order(246571..246573,246739..246741,
                     246748..246753))
                     /locus_tag="COSY_0244"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238347"
     gene            complement(247900..248283)
                     /locus_tag="COSY_0245"
                     /db_xref="GeneID:5171970"
     CDS             complement(247900..248283)
                     /locus_tag="COSY_0245"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219099.1"
                     /db_xref="GI:148244405"
                     /db_xref="GeneID:5171970"
                     /translation="MPISSIGPVLYKISLANACSNLFMLTFSKLSLFLQASCTTSITE
                     ESATVCSTTLEVSINVIVSRLYSLFTTILLKIGSIRPISRSSPPAITSPTNTNIIAKL
                     SILLIIFIPPNYSKINLSTFFESLL"
     gene            complement(248413..248970)
                     /gene="frr"
                     /locus_tag="COSY_0246"
                     /db_xref="GeneID:5172666"
     CDS             complement(248413..248970)
                     /gene="frr"
                     /locus_tag="COSY_0246"
                     /note="Rrf; Frr; ribosome-recycling factor; release factor
                     4; RF4; recycles ribosomes upon translation termination
                     along with release factor RF-3 and elongation factor EF-G;
                     A GTPase-dependent process results in release of 50S from
                     70S; inhibited by release factor RF-1; essential for
                     viability; structurally similar to tRNAs"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="YP_001219100.1"
                     /db_xref="GI:148244406"
                     /db_xref="GeneID:5172666"
                     /translation="MLNEIQQNSQNKMNKSINSLKNAFSKIRASRAHPSLLEQIHINY
                     YGSMVPLSQVANISTEDSRTLKASPWEKDMVSVIEKAIMTSDLGLNPQTIGQVIRIHL
                     PPLTQERRGELVKIIKDEAEKAKIAIRNIRRDANSDFKELLKEKEISKDEARKAEYDI
                     QKITDEYIKKIEINLNKKEDSLLEI"
     misc_feature    complement(248470..248970)
                     /gene="frr"
                     /locus_tag="COSY_0246"
                     /note="ribosome recycling factor; Reviewed; Region: frr;
                     PRK00083"
                     /db_xref="CDD:178850"
     misc_feature    complement(248470..248943)
                     /gene="frr"
                     /locus_tag="COSY_0246"
                     /note="Ribosome recycling factor (RRF). Ribosome recycling
                     factor dissociates the posttermination complex, composed
                     of the ribosome, deacylated tRNA, and mRNA, after
                     termination of translation.  Thus ribosomes are
                     &quot;recycled&quot; and ready for another...; Region:
                     RRF; cd00520"
                     /db_xref="CDD:238288"
     misc_feature    complement(order(248656..248667,248875..248886))
                     /gene="frr"
                     /locus_tag="COSY_0246"
                     /note="hinge region; other site"
                     /db_xref="CDD:238288"
     gene            complement(248974..249687)
                     /gene="pyrH"
                     /locus_tag="COSY_0247"
                     /db_xref="GeneID:5171829"
     CDS             complement(248974..249687)
                     /gene="pyrH"
                     /locus_tag="COSY_0247"
                     /EC_number="2.7.4.-"
                     /note="Catalyzes the phosphorylation of UMP to UDP"
                     /codon_start=1
                     /transl_table=11
                     /product="uridylate kinase"
                     /protein_id="YP_001219101.1"
                     /db_xref="GI:148244407"
                     /db_xref="GeneID:5171829"
                     /translation="MSKYKRILLKLSGEALASTTNIIDPVTLNKIVDIIKSVLSQNIE
                     IAIVIGGGNIFRGETLTKTGINRITSDHIGMLSTIINALAIADTCQKNKVDALVMSGL
                     SIGGGICNSINHIYAKQALKKGKVIIFCAGTGNPCFTTDTGAALRAIEIGADAIFKAT
                     KVDGIYTDDPVKNPNAKRYNSLSFDEAIEKNLQIMDVSAFALCRKHDLEICVFSMLEN
                     TNTLSDLLKGKLLGTIVRK"
     misc_feature    complement(248983..249675)
                     /gene="pyrH"
                     /locus_tag="COSY_0247"
                     /note="UMP kinase (UMPK)-Ec, the microbial/chloroplast
                     uridine monophosphate kinase (uridylate kinase) enzyme
                     that catalyzes UMP phosphorylation and plays a key role in
                     pyrimidine nucleotide biosynthesis; regulation of this
                     process is via feed-back control and...; Region:
                     AAK_UMPK-PyrH-Ec; cd04254"
                     /db_xref="CDD:239787"
     misc_feature    complement(order(249181..249186,249190..249192,
                     249196..249198,249205..249210,249265..249270,
                     249532..249540,249646..249651,249658..249660))
                     /gene="pyrH"
                     /locus_tag="COSY_0247"
                     /note="putative nucleotide binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239787"
     misc_feature    complement(order(249268..249276,249280..249285,
                     249289..249291,249463..249468,249475..249477,
                     249517..249522,249532..249540))
                     /gene="pyrH"
                     /locus_tag="COSY_0247"
                     /note="uridine monophosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239787"
     misc_feature    complement(order(249070..249072,249238..249243,
                     249250..249252,249277..249285,249289..249291,
                     249313..249315,249331..249333,249340..249342,
                     249352..249354,249397..249399,249427..249429,
                     249448..249450,249469..249474,249496..249501))
                     /gene="pyrH"
                     /locus_tag="COSY_0247"
                     /note="homohexameric interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239787"
     gene            249770..252586
                     /gene="uvrA"
                     /locus_tag="COSY_0248"
                     /db_xref="GeneID:5171804"
     CDS             249770..252586
                     /gene="uvrA"
                     /locus_tag="COSY_0248"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
                     /protein_id="YP_001219102.1"
                     /db_xref="GI:148244408"
                     /db_xref="GeneID:5171804"
                     /translation="MDQISIRGARVHNLKNIDIDIPRNKLIVITGLSGSGKSSLAFDT
                     IYAEGHRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIYDYLRLLFARIGIPICPKHKINLESQTISQMVNNIVKLPIGRKIMLLAPIVQNRKG
                     SHVQLLKELNQQGFLRARIDGVVVYIDEMEVLNSKVNHSIEIVVDRLKIREDMISRLS
                     ESLETALNLSAGLVRIAPMEYESSLQEKVFSAKFSCIECGYSLSELEPRLFSFNNPVG
                     ACQTCDGLGVRDTFDEQKVVVSPSMSLADGAVYGWGRSNAYFYQILMLVGKYYGFSIE
                     TPYEQLSNKHKKIVLYGSGTDDIDFSRIKGRKGWSNKAKPFEGIIPRMMRRYETSEIN
                     SVREELSRYVVSKNCTECHGDRLNESARNVFIDEQNLSNITKLSIADIYSFLKEVKLE
                     GVRGQIAEKILKEIIQRLEFLINVGLEYLSLDRRANSLSGGEAQRIRLASQIGAGLMG
                     VLYVLDEPSIGLHQRDNQKLLNTLAYLRDIGNTVIMIEHDEEAIKQADYVIDIGPGAG
                     VHGGEIVAIGIPKDIENNLKSLTGDYLSGRQSIKVPTKRKSANQWIRIKGAKGNSLNN
                     VDLSIPIGVLTCVTGVSGSGKSTLINDTLYALAARELHHAQITPAEYESVEGLNYLDK
                     IVNIDQSPIGRTPRSNPATYTGVFSLVRDLFSQTLEAKLRGYKAGRFSFNVKGGRCEA
                     CKGDGLIKVEMHFLSDIYVSCDVCQGQRYNQQTLEVFYKGKSISQVLGMTVEQAIRFF
                     QSISKIKQKLQTLMEVGLSYITLGQNATTLSGGEAQRIKLAKELSRMDTGRTLYILDE
                     PTTGLHFHDIKLLLSVINRLCERNNTIVIIEHNLDVIKTADWIIDLGPEGGNKGGQII
                     AFGTPEEVAQVKESYTGEYLKTYV"
     misc_feature    249770..252574
                     /gene="uvrA"
                     /locus_tag="COSY_0248"
                     /note="excinuclease ABC subunit A; Reviewed; Region: uvrA;
                     PRK00349"
                     /db_xref="CDD:234734"
     misc_feature    249779..>250120
                     /gene="uvrA"
                     /locus_tag="COSY_0248"
                     /note="ATP-binding cassette domain I of the excision
                     repair protein UvrA; Region: ABC_UvrA_I; cd03270"
                     /db_xref="CDD:213237"
     misc_feature    <251159..251497
                     /gene="uvrA"
                     /locus_tag="COSY_0248"
                     /note="ATP-binding cassette domain I of the excision
                     repair protein UvrA; Region: ABC_UvrA_I; cd03270"
                     /db_xref="CDD:213237"
     misc_feature    251603..252526
                     /gene="uvrA"
                     /locus_tag="COSY_0248"
                     /note="ATP-binding cassette domain II of the excision
                     repair protein UvrA; Region: ABC_UvrA_II; cd03271"
                     /db_xref="CDD:213238"
     gene            complement(253046..253657)
                     /gene="purN"
                     /locus_tag="COSY_0249"
                     /db_xref="GeneID:5171941"
     CDS             complement(253046..253657)
                     /gene="purN"
                     /locus_tag="COSY_0249"
                     /EC_number="2.1.2.2"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="YP_001219103.1"
                     /db_xref="GI:148244409"
                     /db_xref="GeneID:5171941"
                     /translation="MNGVVLISGNGSNLQSIIDHSIAIDLKIRAVISNHTNAYGLKLS
                     EHENIPTHTLSHKNFSSREKFDQALSNIINQYNPEIIILAGFMRILSAEFTHQYSGKI
                     LNTHPSLLPKFKGLNTHQRVIEAKEKQHGVSIHFVTRQLDGGPIIAQTSINIIDTDTK
                     ETLAKRVLLEEHKLFPKVIHWFTQGRLKLKGNQAILDGKILSN"
     misc_feature    complement(253067..253648)
                     /gene="purN"
                     /locus_tag="COSY_0249"
                     /note="phosphoribosylglycinamide formyltransferase;
                     Reviewed; Region: purN; PRK05647"
                     /db_xref="CDD:235544"
     misc_feature    complement(253112..253648)
                     /gene="purN"
                     /locus_tag="COSY_0249"
                     /note="Phosphoribosylglycinamide formyltransferase (GAR
                     transformylase, GART); Region: FMT_core_GART; cd08645"
                     /db_xref="CDD:187714"
     misc_feature    complement(order(253145..253147,253232..253237,
                     253244..253249,253253..253255,253313..253315,
                     253337..253348,253373..253375,253388..253411,
                     253616..253624,253637..253639))
                     /gene="purN"
                     /locus_tag="COSY_0249"
                     /note="active site"
                     /db_xref="CDD:187714"
     misc_feature    complement(order(253145..253147,253337..253339,
                     253343..253345,253403..253408,253619..253624))
                     /gene="purN"
                     /locus_tag="COSY_0249"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187714"
     misc_feature    complement(order(253232..253237,253244..253249,
                     253346..253348,253373..253375,253388..253396,
                     253400..253402,253409..253411))
                     /gene="purN"
                     /locus_tag="COSY_0249"
                     /note="cosubstrate binding site; other site"
                     /db_xref="CDD:187714"
     misc_feature    complement(order(253232..253234,253340..253342,
                     253346..253348))
                     /gene="purN"
                     /locus_tag="COSY_0249"
                     /note="catalytic site [active]"
                     /db_xref="CDD:187714"
     gene            complement(253673..254674)
                     /gene="purM"
                     /locus_tag="COSY_0250"
                     /db_xref="GeneID:5172380"
     CDS             complement(253673..254674)
                     /gene="purM"
                     /locus_tag="COSY_0250"
                     /EC_number="6.3.3.1"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="YP_001219104.1"
                     /db_xref="GI:148244410"
                     /db_xref="GeneID:5172380"
                     /translation="MLSLSYLDSGVNITKGNALIEQIKPIAKSTTRPEVLAGLGGFGA
                     MFELSFNKYKHPILISSTDGVGTKLKIAQMLNKHDTIGIDLVAMCVNDLIVQGAEPLF
                     FLDYYATSKLNTKLATSVIYGIGEGCKQSGCALIGGETAEMPGMYQGEEYDLVGFCVG
                     ITDKNKIINGTKVTIGNHIIALASSGPHSNGYSLIHKVLAQSNPTDEQLNELIKPTRI
                     YVKSILSLIKKFSVHAISHITGGGLLENIPRVFPKNLSAKLDVNSWQLPSIFQFLQDS
                     GNIDMMEMYRVFNCGIGMIIIVPEEQSADAIEYLNEIGEQAWLVGEIKNNQGNQVII"
     misc_feature    complement(253706..254665)
                     /gene="purM"
                     /locus_tag="COSY_0250"
                     /note="phosphoribosylaminoimidazole synthetase;
                     Provisional; Region: PRK05385"
                     /db_xref="CDD:235439"
     misc_feature    complement(253703..254566)
                     /gene="purM"
                     /locus_tag="COSY_0250"
                     /note="PurM (Aminoimidazole Ribonucleotide [AIR]
                     synthetase), one of eleven enzymes required for purine
                     biosynthesis, catalyzes the conversion of
                     formylglycinamide ribonucleotide (FGAM) and ATP to AIR,
                     ADP, and Pi, the fifth step in de novo purine
                     biosynthesis; Region: PurM; cd02196"
                     /db_xref="CDD:100032"
     misc_feature    complement(order(253928..253930,254204..254206,
                     254216..254221,254240..254242,254246..254248,
                     254258..254260,254351..254353,254360..254362,
                     254369..254371,254387..254389,254399..254401,
                     254465..254467,254483..254485,254489..254491,
                     254495..254506,254537..254551))
                     /gene="purM"
                     /locus_tag="COSY_0250"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100032"
     misc_feature    complement(order(254258..254266,254399..254401))
                     /gene="purM"
                     /locus_tag="COSY_0250"
                     /note="putative ATP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100032"
     gene            254728..255294
                     /locus_tag="COSY_0251"
                     /db_xref="GeneID:5172096"
     CDS             254728..255294
                     /locus_tag="COSY_0251"
                     /note="Similar to phosphatidylglycerophosphate synthase
                     PgsA."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219105.1"
                     /db_xref="GI:148244411"
                     /db_xref="GeneID:5172096"
                     /translation="MSFSSLPNLLSILRIILTVPVVMTLLDRQYFLAMVLFFVAGITD
                     ALDGWIAKRYSFQTRLGSILDPIADKLLLVSSFMALYVIRLIPLWLLVLIFLRDFMII
                     SGTVGCFIGSGASKNDLLSPSKLSKINTVLQIILVLFLVIVQIYPVPVQYSTIFFIII
                     ATSTMLSGADYAWIWIEQIILQEKKNPQ"
     misc_feature    254734..254973
                     /locus_tag="COSY_0251"
                     /note="CDP-alcohol phosphatidyltransferase; Region:
                     CDP-OH_P_transf; pfam01066"
                     /db_xref="CDD:216278"
     gene            255291..255965
                     /locus_tag="COSY_0252"
                     /db_xref="GeneID:5172186"
     CDS             255291..255965
                     /locus_tag="COSY_0252"
                     /note="ATPase involved in DNA replication initiation, DnaA
                     family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA family protein"
                     /protein_id="YP_001219106.1"
                     /db_xref="GI:148244412"
                     /db_xref="GeneID:5172186"
                     /translation="MNQLGLPLLLNSKILLSNFIGNKNQQVLDFVNRLFTQKRSAVVF
                     ISGTKSSGKTHLLQGCAFSALDKKLNVAYIDIKQELPKGIISDLTSVDWICIDNVDCL
                     SITQQQALFDLYNRNKPTSVKLIIAASSSPNELNLLKDLKTRLSLAVAFTLEVLNDEQ
                     KILIIERKMADKNININSKVYHYLFKVFSRDLNDILNVISVLEEASLQQKSNISIPFV
                     KQILGI"
     misc_feature    255339..255959
                     /locus_tag="COSY_0252"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cl17189"
                     /db_xref="CDD:247743"
     misc_feature    <255342..>255956
                     /locus_tag="COSY_0252"
                     /note="ATPase involved in DNA replication initiation [DNA
                     replication, recombination, and repair]; Region: DnaA;
                     COG0593"
                     /db_xref="CDD:223666"
     misc_feature    255429..255452
                     /locus_tag="COSY_0252"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(255432..255455,255579..255581,255678..255680)
                     /locus_tag="COSY_0252"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    255567..255584
                     /locus_tag="COSY_0252"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    255720..255722
                     /locus_tag="COSY_0252"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     gene            complement(255962..256369)
                     /locus_tag="COSY_0253"
                     /db_xref="GeneID:5171957"
     CDS             complement(255962..256369)
                     /locus_tag="COSY_0253"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219107.1"
                     /db_xref="GI:148244413"
                     /db_xref="GeneID:5171957"
                     /translation="MSNKHYTCPFDKLIISGRCGCKFSTKDCIAEKEFGVCLDHSYSN
                     QCQLLYTNLRDNSNFVLNIHHQNNLLIRQQLKIKMGGLLALQEKLNIDNSNQIKDISN
                     LVKIIKKKYIDFKKINFSKLMPKIEQFRFREKS"
     gene            256466..257866
                     /gene="cysG"
                     /locus_tag="COSY_0254"
                     /db_xref="GeneID:5172080"
     CDS             256466..257866
                     /gene="cysG"
                     /locus_tag="COSY_0254"
                     /EC_number="1.3.1.76"
                     /EC_number="2.1.1.107"
                     /EC_number="4.99.1.4"
                     /note="Multifunctional uroporphyrin-III
                     C-methyltransferase / precorrin-2 oxidase /
                     ferrochelatase."
                     /codon_start=1
                     /transl_table=11
                     /product="siroheme synthase"
                     /protein_id="YP_001219108.1"
                     /db_xref="GI:148244414"
                     /db_xref="GeneID:5172080"
                     /translation="MNYLPIFIDIKQKPCLVVGGGSIAYRKINLLLKAYGQVTCIAKS
                     SCKNVAKLVNNKKIIYIERSFESSDVNGQVLIISATNNATLNKKVSELASQNNIPVNV
                     IDSPDLCTFIMPSIVDRSPILIAISSAGKAPVLARIIRAKLESTLPHAYGKLAELAGN
                     FRDQVKAKFSRIEDKRYFWEEIFSGIIAEKVFSGKIQEAKADLQAQLNNTVEAQVGAV
                     YLVGGGPGDPDLLTFRALRLMQQADVVLYDRLVSDRVMELVRRDAQLIYVGKECDNHA
                     VPQGDINQLLVDLAKEGRRVCRLKGGDPFIFGRGGEEIETLAENGIPFQVVPGITAAS
                     GCSTYSGIPLTHRDYSQSCRFVTGHLKDGSMNLPWHELAIEQQTIVFYMALNSVEYLS
                     GQLIIHNMRPDMPVALVEKGTTPEQKVYITTLKELPNLVENETIHAPTLIIIGEVVKL
                     REKLNWFDAKPISSKK"
     misc_feature    256466..257836
                     /gene="cysG"
                     /locus_tag="COSY_0254"
                     /note="siroheme synthase; Provisional; Region: cysG;
                     PRK10637"
                     /db_xref="CDD:182606"
     misc_feature    256481..256810
                     /gene="cysG"
                     /locus_tag="COSY_0254"
                     /note="Putative NAD(P)-binding; Region: NAD_binding_7;
                     pfam13241"
                     /db_xref="CDD:222002"
     misc_feature    256910..257089
                     /gene="cysG"
                     /locus_tag="COSY_0254"
                     /note="Sirohaem synthase dimerisation region; Region:
                     CysG_dimeriser; pfam10414"
                     /db_xref="CDD:204480"
     misc_feature    257117..257812
                     /gene="cysG"
                     /locus_tag="COSY_0254"
                     /note="Uroporphyrin-III C-methyltransferase
                     (S-Adenosyl-L-methionine:uroporphyrinogen III
                     methyltransferase, SUMT); Region: SUMT; cd11642"
                     /db_xref="CDD:212501"
     misc_feature    order(257138..257140,257207..257215,257366..257374,
                     257381..257392,257456..257461,257471..257473,
                     257534..257536,257540..257542,257606..257620,
                     257690..257692,257696..257701,257705..257707,
                     257777..257788)
                     /gene="cysG"
                     /locus_tag="COSY_0254"
                     /note="active site"
                     /db_xref="CDD:212501"
     misc_feature    order(257138..257140,257366..257374,257381..257386,
                     257456..257461,257609..257611,257690..257692,
                     257696..257701,257780..257788)
                     /gene="cysG"
                     /locus_tag="COSY_0254"
                     /note="SAM binding site [chemical binding]; other site"
                     /db_xref="CDD:212501"
     misc_feature    order(257150..257167,257171..257173,257372..257374,
                     257378..257386,257396..257401,257405..257407,
                     257417..257422,257441..257443,257447..257449,
                     257453..257455,257465..257470,257492..257494,
                     257498..257506,257516..257530)
                     /gene="cysG"
                     /locus_tag="COSY_0254"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:212501"
     gene            complement(257902..258105)
                     /locus_tag="COSY_0255"
                     /db_xref="GeneID:5172168"
     CDS             complement(257902..258105)
                     /locus_tag="COSY_0255"
                     /note="Rhodanese-related sulfurtransferase putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219109.1"
                     /db_xref="GI:148244415"
                     /db_xref="GeneID:5172168"
                     /translation="MTINNVVSAVAGVVIIISLLLGAQEISPFAYNSNWLWLTVFVGF
                     NLFQSAFTGFCPAAIIAKKLGAK"
     misc_feature    complement(257917..>258021)
                     /locus_tag="COSY_0255"
                     /note="Protein of unknown function (DUF2892); Region:
                     DUF2892; pfam11127"
                     /db_xref="CDD:220991"
     gene            258203..258287
                     /locus_tag="COSY_t10"
                     /db_xref="GeneID:5329731"
     tRNA            258203..258287
                     /locus_tag="COSY_t10"
                     /product="tRNA-Leu"
                     /db_xref="GeneID:5329731"
     gene            258304..259113
                     /gene="serB"
                     /locus_tag="COSY_0257"
                     /db_xref="GeneID:5172055"
     CDS             258304..259113
                     /gene="serB"
                     /locus_tag="COSY_0257"
                     /EC_number="3.1.3.3"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="YP_001219110.1"
                     /db_xref="GI:148244416"
                     /db_xref="GeneID:5172055"
                     /translation="MSMTIIIQHSLDENIAKKISSKFQVFNTHIRHKIVSANLDDLRQ
                     QYQIDFNYLPKLDLSSIQLFVSDMDSTLINIECIDEIADFANIKREVGVITELTMQGK
                     LDFGSSLFKRVSLLKGLSVDVLDKVYTQRLSVSPGGRSLISFFKTKFIKTAIVSGGFT
                     YFTNRLVKDLALDYACANVLSIENNQLTGVTEGLMINAQAKSDFVKALCDKQGWSYSQ
                     VIVVGDGVNDLDMMNIAGLSVAYHAKPSVIKHVDIIINFGGLDKIIDLFNQ"
     misc_feature    258475..259101
                     /gene="serB"
                     /locus_tag="COSY_0257"
                     /note="phosphoserine phosphatase SerB; Region: serB;
                     TIGR00338"
                     /db_xref="CDD:232927"
     misc_feature    258676..259023
                     /gene="serB"
                     /locus_tag="COSY_0257"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    258769..258771
                     /gene="serB"
                     /locus_tag="COSY_0257"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     gene            259120..261027
                     /gene="ccmF"
                     /locus_tag="COSY_0258"
                     /db_xref="GeneID:5171885"
     CDS             259120..261027
                     /gene="ccmF"
                     /locus_tag="COSY_0258"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis protein CcmF"
                     /protein_id="YP_001219111.1"
                     /db_xref="GI:148244417"
                     /db_xref="GeneID:5171885"
                     /translation="MLIEIGHFALVLALVFAMLQVILPTIGMIKYDVVLSSLSRPLLW
                     MQFFWILIAFVILVNAFVVDDFSVRYVASNSNTQLPNIFKMSAIWGAHEGSLLLWALI
                     LAAWSVAVSLFSRRLPVEVLNHILIILGLISIGFLLFLLLTSNPFERLDIVPLQGREL
                     NPLLQDFGLIIHPPMLYMGYVGMAIPFAFVVSSLIRGQLDSTWLRWSRPWTLIAWAFL
                     TLGITLGSWWAYYELGWGGWWFWDPVENASFMPWLVATALVHSLSVSEKRSAFKHWTV
                     LLAISSFSLSLLGTFLVRSGILTSVHSFATDPDRGLFVLIFLVIVIGGSLVLYAWRAT
                     LLMQSSNTFSLLSRESGLLVNNILLVASMLSVFLGTFYPLLLDALGLGKISVGAPYFG
                     SVFVPIMILAILIMAIIPFLRWKEDTTQRVVDLLKRVWIGVGLLFVISVFLIDNILVL
                     LAVFLFIWIVSHSLVLLFQRLGQKGSINLAFIGMIFAHIGIAVFLLGATVTTQYGVEK
                     DIQMEIDKPITIKGYDFIFKGVTRLFGPNYQGNKGHVEVYFEDEKIADLRPEKRQYTT
                     GMPMTEASIDSSLYRDIYIALGESLEDDSWSLRIYYKPLVRWIWLGGLLISLGALLSA
                     FDRRYRLRIKE"
     misc_feature    259120..261015
                     /gene="ccmF"
                     /locus_tag="COSY_0258"
                     /note="Cytochrome c biogenesis factor [Posttranslational
                     modification, protein turnover, chaperones]; Region: CcmF;
                     COG1138"
                     /db_xref="CDD:224061"
     gene            261024..262190
                     /locus_tag="COSY_0259"
                     /db_xref="GeneID:5172017"
     CDS             261024..262190
                     /locus_tag="COSY_0259"
                     /note="Similar to cytochrome c-type biogenesis protein.
                     TPR repeat domain protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219112.1"
                     /db_xref="GI:148244418"
                     /db_xref="GeneID:5172017"
                     /translation="MSLYLWFALMVIVSFIWIIWFLYRPIKSNKFNLESSNISLGKQK
                     LLELEQDLHQNLIDKKQFNQAKEEISITLAIELKQANSINTSTNNNILIIVLILVLLP
                     VMSIGFYQYLTSKNNMNQSSSNTEESLSLEQSVNKIVQYLQTNRDDAEAWRMLGLTYF
                     ELGELDLSINAYEKSFQINPKDPRLLVEYASIMISANGHQFSNHSIKLIKQALEIDPN
                     ASDSLYLAGMFAARQGDFDLAKGLWQRALNALPKDSINRVALVNILSELKVLESSRDM
                     SKHFISVRVNVSDEILKFRSSEDFIMIYVKAAKGRAMPIAIKKIKLKVFTGQVVLTDQ
                     DSVIQDNQLSAYDQVIVVVRISATGSAIRSIDDIQVLSKVINVADNPSVYLNMK"
     misc_feature    261042..261812
                     /locus_tag="COSY_0259"
                     /note="Cytochrome c biogenesis factor [Posttranslational
                     modification, protein turnover, chaperones]; Region:
                     COG4235"
                     /db_xref="CDD:226687"
     misc_feature    261042..>261263
                     /locus_tag="COSY_0259"
                     /note="cytochrome c-type biogenesis protein CcmI; Region:
                     cytochro_ccmI; TIGR03142"
                     /db_xref="CDD:163153"
     misc_feature    261471..261779
                     /locus_tag="COSY_0259"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cd00189"
                     /db_xref="CDD:238112"
     misc_feature    order(261471..261476,261480..261485,261492..261497,
                     261582..261587,261591..261593,261600..261602,
                     261609..261614,261693..261698,261705..261710,
                     261717..261722)
                     /locus_tag="COSY_0259"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     misc_feature    order(261489..261491,261525..261527,261537..261539,
                     261546..261548,261591..261593,261636..261638,
                     261648..261650,261657..261659,261702..261704,
                     261738..261740,261750..261752,261759..261761)
                     /locus_tag="COSY_0259"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     gene            262195..263325
                     /gene="dapE"
                     /locus_tag="COSY_0260"
                     /db_xref="GeneID:5172026"
     CDS             262195..263325
                     /gene="dapE"
                     /locus_tag="COSY_0260"
                     /EC_number="3.5.1.18"
                     /note="dapE-encoded N-succinyl-L,L-diaminopimelic acid
                     desuccinylase (DapE), catalyzes the hydrolysis of
                     N-succinyl-L,Ldiaminopimelate L,L-SDAP to
                     L,L-diaminopimelate and succinate. It is a metalloprotease
                     containing dinuclear active sites. Its structure is
                     similar to the carboxypeptidase G2 from Pseudomonas sp.
                     strain RS-16 and the aminopeptidase from Aeromonas
                     proteolytica."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="YP_001219113.1"
                     /db_xref="GI:148244419"
                     /db_xref="GeneID:5172026"
                     /translation="MSKTLTLAKKLVSIDSITPQDKGCQSIMISHLNDLNFEITDLKF
                     GEVDNFWAIRGQQSPVFVFAGHTDVVPVGNESEWHMPPFSAQVKNGMLYGRGTSDMKG
                     SLAAMLSATDRFVKDHSNHKGSIGYLITSDEEGPAINGTVKVAQYLKKINQTVDYCLV
                     GEPSATHELGDIIKNGRRGSLNGSFKIIGKQGHIAYPHLASNPIHLVIPALNDLCNEV
                     WDEGNEYFPATSFQISNIQSGTGVTNVIPGESNIVFNFRYSTQCTQEQLQSRVCAILD
                     KRNFEYQITWEHSGYPFLTPKGKLVNACVNAIKTVKNINTQLSTSGGTSDGRFIAPIL
                     KTRVIELGPSNATIHQVNECVSIQDLEDLSDIYYHILKNILT"
     misc_feature    262195..263322
                     /gene="dapE"
                     /locus_tag="COSY_0260"
                     /note="succinyl-diaminopimelate desuccinylase; Reviewed;
                     Region: PRK13009"
                     /db_xref="CDD:237265"
     misc_feature    262207..263307
                     /gene="dapE"
                     /locus_tag="COSY_0260"
                     /note="M20 Peptidase proteobacterial DapE encoded
                     N-succinyl-L,L-diaminopimelic acid desuccinylase; Region:
                     M20_DapE_proteobac; cd03891"
                     /db_xref="CDD:193511"
     misc_feature    order(262390..262392,262489..262491,262591..262596,
                     262678..262680,263239..263241)
                     /gene="dapE"
                     /locus_tag="COSY_0260"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:193511"
     misc_feature    order(262738..262740,262771..262782,262798..262800,
                     262804..262809,262816..262821,262825..262830,
                     262837..262839,262882..262884,262888..262911,
                     262930..262935,262957..262959,262963..262965,
                     263158..263160)
                     /gene="dapE"
                     /locus_tag="COSY_0260"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:193511"
     gene            263329..264003
                     /gene="trmD"
                     /locus_tag="COSY_0261"
                     /db_xref="GeneID:5172188"
     CDS             263329..264003
                     /gene="trmD"
                     /locus_tag="COSY_0261"
                     /EC_number="2.1.1.31"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N1-)-methyltransferase"
                     /protein_id="YP_001219114.1"
                     /db_xref="GI:148244420"
                     /db_xref="GeneID:5172188"
                     /translation="MRFDIITLFPNMFNIIKDEGVVARAIKKSHLSVHIWQLRDFSNN
                     KYKNIDDKPYGGGGGMVMQVKPIRDCINKIKQSSPKTKIIYLSPQGQPLKHKLTKELS
                     MFDAITLLCGRYEGVDERIINHDIDMEISIGDYIISGGELAAMVLIDTVSRQIPNVLG
                     NINSLNDSFTNNLLDYPNYTRPKIIDNQKVPEVLLSGHQANINIWRIEQSIKKTKKKR
                     KDLLKN"
     misc_feature    263329..263961
                     /gene="trmD"
                     /locus_tag="COSY_0261"
                     /note="tRNA (guanine-N(1)-)-methyltransferase; Reviewed;
                     Region: trmD; PRK00026"
                     /db_xref="CDD:234581"
     gene            264163..264501
                     /gene="glnK"
                     /locus_tag="COSY_0262"
                     /db_xref="GeneID:5172200"
     CDS             264163..264501
                     /gene="glnK"
                     /locus_tag="COSY_0262"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein PII"
                     /protein_id="YP_001219115.1"
                     /db_xref="GI:148244421"
                     /db_xref="GeneID:5172200"
                     /translation="MKFVTAILRPHKLDSVREALSEVGVSGVTVTEVKGFGRQKGHTE
                     LYRGTEYQIDFLPKIKLEIAIEAKKLDEVIEMISSVTNSGKVGDGKIFVSNLDKVVRI
                     RTGETDKNAL"
     misc_feature    264163..264498
                     /gene="glnK"
                     /locus_tag="COSY_0262"
                     /note="Nitrogen regulatory protein PII [Amino acid
                     transport and metabolism]; Region: GlnK; COG0347"
                     /db_xref="CDD:223424"
     misc_feature    264172..264477
                     /gene="glnK"
                     /locus_tag="COSY_0262"
                     /note="Nitrogen regulatory protein P-II; Region: P-II;
                     smart00938"
                     /db_xref="CDD:198006"
     gene            264491..265786
                     /gene="amtB"
                     /locus_tag="COSY_0263"
                     /db_xref="GeneID:5172688"
     CDS             264491..265786
                     /gene="amtB"
                     /locus_tag="COSY_0263"
                     /note="ammonium or ammonia transporter (Amt) family"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="YP_001219116.1"
                     /db_xref="GI:148244422"
                     /db_xref="GeneID:5172688"
                     /translation="MHFKELVVKKLLVTLAYLPMSVFSQDINGADTAWIMTSTALVLL
                     MTLPGLALFYGGLVRTKNILSVLMQCFTIAGIVSILWFVVGYSIAFSGDSPYFGDFSN
                     ILLMKVSINMINNSIPESLFVMFQMTFAIITPALIIGGYAERMKFSAVLLFSSIWLLV
                     VYAPITHWVWGGGWLGNMLDYAGGTVVHITAGIAALVAAIVLGPRKGFLKRPIPPHNM
                     TMTITGAAMLWVGWFGFNGGSALAVGGNAAMAILVTHISAATGAITWMFYEWIKFGRP
                     TALGTVTGMVAGLGTITPASGFVGPVGALVIGFIAGIVCFNAVIIIKQKFKIDDSLDV
                     FPVHGVGGIMGTLMVGFFASKELGIFSGQGGWDHEAILIYEQLQIQFIGVVATVIYTA
                     IATYLILKIVNVITGLRVSEEEEQQGLDIISHEEKGYDL"
     misc_feature    264569..265783
                     /gene="amtB"
                     /locus_tag="COSY_0263"
                     /note="Ammonia permease [Inorganic ion transport and
                     metabolism]; Region: AmtB; COG0004"
                     /db_xref="CDD:223083"
     gene            265930..266790
                     /gene="dapA"
                     /locus_tag="COSY_0264"
                     /db_xref="GeneID:5172089"
     CDS             265930..266790
                     /gene="dapA"
                     /locus_tag="COSY_0264"
                     /EC_number="4.2.1.52"
                     /note="catalyzes the formation of dihydrodipicolinate from
                     L-aspartate 4-semialdehyde and pyruvate in lysine and
                     diaminopimelate biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase"
                     /protein_id="YP_001219117.1"
                     /db_xref="GI:148244423"
                     /db_xref="GeneID:5172089"
                     /translation="MVALITPMFDDGSIDFSALKSLVAFHIDAGTKAIVSMGTTGESA
                     TLNQDEHIEVIRATVEFANSCIPVIAGTGANSTSEAIKLTKVAKEIGADACLLVTPYY
                     NKPTQEGLYQHYKLIAETVDIYQILYNVPSRTAVDLSVETVIRLSDINNIIGIKDATG
                     NLNIAQSLIEQCSDDFLLYSGDDATAVEFILMGGHGGISVTANVAPKQVAFAYQFALE
                     NKRELAELTNESLIDLHQHLFSESNPIPVKWAMYKMGKCNNGIRLPLMTLSKQAKMIL
                     EQDLSNLGII"
     misc_feature    265930..266769
                     /gene="dapA"
                     /locus_tag="COSY_0264"
                     /note="Dihydrodipicolinate synthase (DHDPS); Region:
                     DHDPS; cd00950"
                     /db_xref="CDD:188637"
     misc_feature    265933..266778
                     /gene="dapA"
                     /locus_tag="COSY_0264"
                     /note="dihydrodipicolinate synthase; Region: dapA;
                     TIGR00674"
                     /db_xref="CDD:129757"
     misc_feature    order(266041..266055,266152..266154,266158..266160,
                     266227..266235,266320..266322,266326..266328,
                     266656..266661,266713..266715,266719..266721)
                     /gene="dapA"
                     /locus_tag="COSY_0264"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188637"
     misc_feature    order(266044..266049,266311..266313,266326..266328,
                     266395..266397,266470..266472,266476..266478)
                     /gene="dapA"
                     /locus_tag="COSY_0264"
                     /note="active site"
                     /db_xref="CDD:188637"
     misc_feature    266395..266397
                     /gene="dapA"
                     /locus_tag="COSY_0264"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188637"
     gene            266793..267926
                     /locus_tag="COSY_0265"
                     /db_xref="GeneID:5172178"
     CDS             266793..267926
                     /locus_tag="COSY_0265"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219118.1"
                     /db_xref="GI:148244424"
                     /db_xref="GeneID:5172178"
                     /translation="MVIRGLIALFLVFSLGGCLSLGNKEGQKHNGIGGRDVEYYSKKI
                     LTSLEIPPDLTKPSVKNSLKLGKYVSNFQEDLVNFSKQDSSIKKVSNILRTPTNVEVI
                     KSSSFRWLVVDKEPDVVWELAKSFFQFYGFVIKKASKKTGIMETNFLENHPEISNQSL
                     GFIRSMFRKVTKMKYTLPVADKYRLRIEPIDDNKSAVYLSLSSMQEVLTNKGGDDENT
                     IWQAQSKDPILETEMLYRLMIFLGSDHVLAKEKILAAREQQILTVVVAKGVGGYAKLV
                     FPLTQYETWSNISWALDQIGADIEDKDIREGSFYINFAKEEDESIFSRLFSNSVIKES
                     FQIVVRQVDSNITEVYFNDLSEENKQTTIDFSYQFLGDIAKQF"
     misc_feature    266808..267752
                     /locus_tag="COSY_0265"
                     /note="Uncharacterized lipoprotein [Cell envelope
                     biogenesis, outer membrane]; Region: NlpB; COG3317"
                     /db_xref="CDD:225854"
     gene            267941..269839
                     /gene="lig"
                     /locus_tag="COSY_0266"
                     /db_xref="GeneID:5172050"
     CDS             267941..269839
                     /gene="lig"
                     /locus_tag="COSY_0266"
                     /EC_number="6.5.1.2"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA ligase (NAD+)"
                     /protein_id="YP_001219119.1"
                     /db_xref="GI:148244425"
                     /db_xref="GeneID:5172050"
                     /translation="MLSQNIIDKIIRQDILVDELLDEELSIFCQTANLAYRSGKPIIS
                     NEDYDFIYLATLKNKEPNNPLFKSIEPEGRAFAEEKVLLPELMLSIDKAYSWNEMSKW
                     IERLEKSGMLIGLDLNAIQIKATPKLDGFAGFDDGNRLYTRGDGKKGSDISRVFKRGL
                     CVFKDSGRGLGAGEIVVKKSYFEKYLVHSFEYPRNFQSSLIKEKALDEQAQKAIIDKG
                     ALFVPFIKLPIWSGSMTELVAKFEEIVSQVLVMVDFDVDGVVFEVINIDLKTQMGANR
                     KFHRWQIAFKENKDIVQVKVLNVMPQVGRSGKITPVAEVEPTLLSGATIVRVTGHHYG
                     LVKEQGLGIGSVVELTRSGLVIPKIISVLKPMPVDIPDNCLSCGMPLVWESDFLVCVN
                     HKNCPAQIIGRITYFFKVLANNDGFGIATVEKLYAHNIRSVSQIYTLNVERLMAIGFG
                     EKTSINLISQLSRSISEKIEDWRFLAAFGMHRMGLGNCENLLKSYRLNDIFDLTLEQI
                     TNIDGFAELTAQVIVQGLVSIVDEYNQIYQYNFNLDTTVFTKDLQTLMHELFDKRIVF
                     TGKMNCPRNEMKKHAKLVGIKVSTTISTKIDYLVIGSRVGQKKIQNAEKLGVVVMTEA
                     DYLSKITM"
     misc_feature    268046..>268399
                     /gene="lig"
                     /locus_tag="COSY_0266"
                     /note="NAD+ dependent DNA ligase adenylation domain. DNA
                     ligases catalyze the crucial step of joining the breaks in
                     duplex DNA during DNA replication, repair and
                     recombination, utilizing either ATP or NAD(+) as a
                     cofactor, but using the same basic reaction...; Region:
                     LIGANc; cl03295"
                     /db_xref="CDD:243376"
     misc_feature    268085..269815
                     /gene="lig"
                     /locus_tag="COSY_0266"
                     /note="NAD-dependent DNA ligase LigA; Provisional; Region:
                     ligA; PRK14350"
                     /db_xref="CDD:172826"
     misc_feature    order(268208..268210,268313..268315,268319..268321,
                     268367..268369)
                     /gene="lig"
                     /locus_tag="COSY_0266"
                     /note="nucleotide binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238062"
     misc_feature    order(268319..268321,268325..268330)
                     /gene="lig"
                     /locus_tag="COSY_0266"
                     /note="K-X-D-G motif; other site"
                     /db_xref="CDD:238062"
     misc_feature    268319..268321
                     /gene="lig"
                     /locus_tag="COSY_0266"
                     /note="catalytic site [active]"
                     /db_xref="CDD:238062"
     misc_feature    268814..269032
                     /gene="lig"
                     /locus_tag="COSY_0266"
                     /note="NAD-dependent DNA ligase OB-fold domain; Region:
                     DNA_ligase_OB; pfam03120"
                     /db_xref="CDD:145978"
     misc_feature    269621..269809
                     /gene="lig"
                     /locus_tag="COSY_0266"
                     /note="Breast Cancer Suppressor Protein (BRCA1),
                     carboxy-terminal domain. The BRCT domain is found within
                     many DNA damage repair and cell cycle checkpoint proteins.
                     The unique diversity of this domain superfamily allows
                     BRCT modules to interact forming homo...; Region: BRCT;
                     cd00027"
                     /db_xref="CDD:237994"
     misc_feature    order(269663..269665,269675..269677,269684..269686,
                     269693..269695,269699..269701)
                     /gene="lig"
                     /locus_tag="COSY_0266"
                     /note="Dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:237994"
     gene            270118..270465
                     /locus_tag="COSY_0267"
                     /db_xref="GeneID:5172571"
     CDS             270118..270465
                     /locus_tag="COSY_0267"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein PII"
                     /protein_id="YP_001219120.1"
                     /db_xref="GI:148244426"
                     /db_xref="GeneID:5172571"
                     /translation="MKMVTAIIKPFKLENVREALSEIGISGITATEVKGFGRQKGHTE
                     LYRGAEYTVDFLPKVKLEIAIVADQVDNVVKVISTAAKSGDEGKIGDGKIFVSSLEQV
                     LRIRTGETGSIAL"
     misc_feature    270118..270462
                     /locus_tag="COSY_0267"
                     /note="Nitrogen regulatory protein PII [Amino acid
                     transport and metabolism]; Region: GlnK; COG0347"
                     /db_xref="CDD:223424"
     misc_feature    270127..270441
                     /locus_tag="COSY_0267"
                     /note="Nitrogen regulatory protein P-II; Region: P-II;
                     smart00938"
                     /db_xref="CDD:198006"
     gene            270885..271547
                     /locus_tag="COSY_0268"
                     /db_xref="GeneID:5171998"
     CDS             270885..271547
                     /locus_tag="COSY_0268"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219121.1"
                     /db_xref="GI:148244427"
                     /db_xref="GeneID:5171998"
                     /translation="MKKNIIILLLCLISIFNSVSLAEAKIQSAVSANITIANDYVWRG
                     KTQTNDKKVVQIGLDYNVGNGAVLGIWSSNVLNGTEFDYYISYSGEVGDIDYEVGYIA
                     YRYSEDAIVNRLNFDEVYIGGSYSDLGFTYYIGNGKKMLKVGNYVEASYNNSINDIDV
                     SLTVGRYFEAVTGDSNDYNVYGISLERSYKGLDLTLRFVKNNSHNIFNEKNTVFSISK
                     SF"
     misc_feature    270885..271544
                     /locus_tag="COSY_0268"
                     /note="Bacterial protein of unknown function (Gcw_chp);
                     Region: Gcw_chp; cl09901"
                     /db_xref="CDD:245189"
     gene            271639..272079
                     /locus_tag="COSY_0269"
                     /db_xref="GeneID:5172081"
     CDS             271639..272079
                     /locus_tag="COSY_0269"
                     /note="Similar to inosine-5-monophosphate dehydrogenase."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219122.1"
                     /db_xref="GI:148244428"
                     /db_xref="GeneID:5172081"
                     /translation="MQVQEIMSTNVKTVTPDQLVKDIAIIMVMDHISGAPVVDVNNTL
                     VGIISEKDILQHMFPKLDEVMSDTYFDFENMEHNYKDTMNVRVGELMTKEVASIDLNM
                     PCLKAASTMWLKNFRRIPITHNNKLVGIVSIGDVHRAIFKSRIK"
     misc_feature    271645..272046
                     /locus_tag="COSY_0269"
                     /note="FOG: CBS domain [General function prediction only];
                     Region: COG0517"
                     /db_xref="CDD:223591"
     misc_feature    271663..272055
                     /locus_tag="COSY_0269"
                     /note="The CBS domain, named after human CBS, is a small
                     domain originally identified in cystathionine
                     beta-synthase and is subsequently found in a wide range of
                     different proteins. CBS domains usually occur in tandem
                     repeats. They associate to form a so-called...; Region:
                     CBS_pair; cl15354"
                     /db_xref="CDD:246936"
     gene            272076..272663
                     /gene="nasT"
                     /locus_tag="COSY_0270"
                     /db_xref="GeneID:5172203"
     CDS             272076..272663
                     /gene="nasT"
                     /locus_tag="COSY_0270"
                     /note="histidine kinase/response regulator hybrid protein"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator NasT"
                     /protein_id="YP_001219123.1"
                     /db_xref="GI:148244429"
                     /db_xref="GeneID:5172203"
                     /translation="MNIALKIILVDKNTGRSAMLRRALQDKGHEVICRMRDSSNLQDS
                     NEMTHADVLIVNADIPDEQVFANLIDINKTKPKPIVMFTKESNSEMANSAIKSGVHAY
                     IVDGLEENRVQPIIDVAIARFREFQALKDELDATRNQLSERKKVEKAKGLLMQHNKDI
                     NEDEAYQSLRKMAMNKNKRIVDVAESVINAFELLE"
     misc_feature    272088..272657
                     /gene="nasT"
                     /locus_tag="COSY_0270"
                     /note="Response regulator with putative antiterminator
                     output domain [Signal transduction mechanisms]; Region:
                     AmiR; COG3707"
                     /db_xref="CDD:226230"
     misc_feature    272091..>272264
                     /gene="nasT"
                     /locus_tag="COSY_0270"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    272469..272639
                     /gene="nasT"
                     /locus_tag="COSY_0270"
                     /note="ANTAR domain; Region: ANTAR; pfam03861"
                     /db_xref="CDD:202788"
     gene            complement(272682..273503)
                     /gene="tatC"
                     /locus_tag="COSY_0271"
                     /db_xref="GeneID:5171966"
     CDS             complement(272682..273503)
                     /gene="tatC"
                     /locus_tag="COSY_0271"
                     /codon_start=1
                     /transl_table=11
                     /product="sec-independent protein translocase protein
                     TatC"
                     /protein_id="YP_001219124.1"
                     /db_xref="GI:148244430"
                     /db_xref="GeneID:5171966"
                     /translation="MINKEMTFVQHLVELRKILLHSVIVILIIFMSIFPFANEVYSFI
                     AAPIINVLPQDTNIIAIGIISPFLTPLKMSLIISVYVAMPYLLYKIWSFIAPALYKHE
                     KQMILPLVVSTTILFYAGLLFSFYIVFPVIFGFLSSIGPNIVDFTPDIQYYLDFVLKV
                     SFAFGVAFEVPIATILLIIFGITTVEKLKNNRPYIIIGAFILGMLLTPPDIISQTLIA
                     IPIWLLFEAGLIFSPLFKQNKQEISNNYPKNSNKTNSKEKKVSDNDDWNKNKIEN"
     misc_feature    complement(272808..273479)
                     /gene="tatC"
                     /locus_tag="COSY_0271"
                     /note="Sec-independent protein translocase protein (TatC);
                     Region: TatC; cl00521"
                     /db_xref="CDD:241922"
     gene            complement(273503..273784)
                     /locus_tag="COSY_0272"
                     /db_xref="GeneID:5172240"
     CDS             complement(273503..273784)
                     /locus_tag="COSY_0272"
                     /note="Similar to the N-terminal region of Bordetella
                     pertussis sec-independent protein translocase protein TatB
                     (147 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219125.1"
                     /db_xref="GI:148244431"
                     /db_xref="GeneID:5172240"
                     /translation="MFDVGFWEFSLIGIITLIIVGPKRMPEIVKEVGTYIGKVKRFII
                     NIQDDISDELEIEKLKKHLNSMDKKSNILEVIDETKNTLNDIKNNIDQK"
     misc_feature    complement(<273539..273784)
                     /locus_tag="COSY_0272"
                     /note="mttA/Hcf106 family; Region: MttA_Hcf106; cl00788"
                     /db_xref="CDD:242093"
     gene            complement(273788..273997)
                     /locus_tag="COSY_0273"
                     /db_xref="GeneID:5172705"
     CDS             complement(273788..273997)
                     /locus_tag="COSY_0273"
                     /note="Similar to the N-terminal region of sec-independent
                     protein translocase protein TatA (73 aa) in Idiomarina
                     loihiensis L2TR."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219126.1"
                     /db_xref="GI:148244432"
                     /db_xref="GeneID:5172705"
                     /translation="MMPGPFELIIILVIVLLLFGGKRLKDIGGDLGNAIKGFKKAMKE
                     STDSINNKDDIVEAKIIKKEIKQEK"
     misc_feature    complement(<273854..>273943)
                     /locus_tag="COSY_0273"
                     /note="mttA/Hcf106 family; Region: MttA_Hcf106; cl00788"
                     /db_xref="CDD:242093"
     gene            complement(274015..274332)
                     /gene="hisE"
                     /locus_tag="COSY_0274"
                     /db_xref="GeneID:5172141"
     CDS             complement(274015..274332)
                     /gene="hisE"
                     /locus_tag="COSY_0274"
                     /EC_number="3.6.1.31"
                     /note="catalyzes the formation of 1-(5-phosphoribosyl)-AMP
                     from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-ATP pyrophosphatase"
                     /protein_id="YP_001219127.1"
                     /db_xref="GI:148244433"
                     /db_xref="GeneID:5172141"
                     /translation="MDEILIKLEQILEQRKSAKADKSYVSSLYNKGTDEILKKISEES
                     AEVIMATKDGSNDKIIYEIADLWFHTLVLLRFKKIKVEQITNELSRRFGLSGLKEKAN
                     RNN"
     misc_feature    complement(274069..274320)
                     /gene="hisE"
                     /locus_tag="COSY_0274"
                     /note="Nucleoside Triphosphate Pyrophosphohydrolase (EC
                     3.6.1.8) MazG-like domain found in Escherichia coli
                     phosphoribosyl-ATP pyrophosphohydrolase (HisIE or
                     PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like;
                     cd11534"
                     /db_xref="CDD:212141"
     misc_feature    complement(order(274138..274140,274147..274149,
                     274195..274197,274204..274206))
                     /gene="hisE"
                     /locus_tag="COSY_0274"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:212141"
     gene            complement(274325..274705)
                     /gene="hisI"
                     /locus_tag="COSY_0275"
                     /db_xref="GeneID:5172405"
     CDS             complement(274325..274705)
                     /gene="hisI"
                     /locus_tag="COSY_0275"
                     /EC_number="3.5.4.19"
                     /note="PR-AMP cyclohydrolase; functions in histidine
                     biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP
                     to
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxyamide during the histidine biosynthesis pathway;
                     binds zinc and magnesium; forms homodimers"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="YP_001219128.1"
                     /db_xref="GI:148244434"
                     /db_xref="GeneID:5172405"
                     /translation="MSALKQIKFDEKGLIPAISQDFKTGEILMFAWMNQESLKLTIKK
                     QQAVYYSRSRQKIWFKGEESGHIQHIKEIFTDCDNDVILLKIEQIGGISCHTGRISCF
                     FQQLDKKNWKIITNMIKNPRDIYG"
     misc_feature    complement(274328..274705)
                     /gene="hisI"
                     /locus_tag="COSY_0275"
                     /note="phosphoribosyl-AMP cyclohydrolase; Reviewed;
                     Region: hisI; PRK00051"
                     /db_xref="CDD:234598"
     gene            complement(274829..276160)
                     /gene="gor"
                     /locus_tag="COSY_0276"
                     /db_xref="GeneID:5172250"
     CDS             complement(274829..276160)
                     /gene="gor"
                     /locus_tag="COSY_0276"
                     /EC_number="1.8.1.7"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione oxidoreductase"
                     /protein_id="YP_001219129.1"
                     /db_xref="GI:148244435"
                     /db_xref="GeneID:5172250"
                     /translation="MNKDYDMIVIGAGSGGLSVIERAAEYGKKCLVIEVKTIGGTCVN
                     TGCVPKKIMWFAANTGTIIKNSKGFGFDVEQKGFSWKKLKTKRDNYIKSITNWYKEHL
                     EKLGIDYIQGFGKLVNKNTVSVNDKQYTAHHIVLSPGGEPSVPHIKGAKYGITSDGFF
                     TLEELPKKVAVIGSGYIGIELAGMLNSLGSKVAIFSRANKLLRGFDYMIQDALNKDYL
                     NHGITIHHNTQIKKISKDKTILTNKGEFSGFDTIIWAVGRNPITKYLGLDNVGVKYDQ
                     KGFIPTDKFQATNIDNIFALGDATPQTPLTPVAIAAGRRLSDRLYNNMVNRHLDYNNI
                     ATVVFSHPPIGTIGLTETQANKKFNKVKIYKSEFTPMADALLNHKTTTVLKLVCMGDD
                     EKIIGCHLMGHGIDEMLQGFAVAIKMGATKAQFDDTIAIHPTSAEELVTMR"
     misc_feature    complement(274832..276160)
                     /gene="gor"
                     /locus_tag="COSY_0276"
                     /note="glutathione reductase; Validated; Region: PRK06116"
                     /db_xref="CDD:235701"
     misc_feature    complement(<276062..276148)
                     /gene="gor"
                     /locus_tag="COSY_0276"
                     /note="Anaerobic glycerol-3-phosphate dehydrogenase [Amino
                     acid transport and metabolism]; Region: GlpB; cl17730"
                     /db_xref="CDD:248284"
     misc_feature    complement(275570..>275788)
                     /gene="gor"
                     /locus_tag="COSY_0276"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; cl17500"
                     /db_xref="CDD:248054"
     misc_feature    complement(275447..275659)
                     /gene="gor"
                     /locus_tag="COSY_0276"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:215691"
     misc_feature    complement(274832..275161)
                     /gene="gor"
                     /locus_tag="COSY_0276"
                     /note="Pyridine nucleotide-disulphide oxidoreductase,
                     dimerisation domain; Region: Pyr_redox_dim; pfam02852"
                     /db_xref="CDD:217252"
     gene            complement(277039..277422)
                     /locus_tag="COSY_0277"
                     /db_xref="GeneID:5171961"
     CDS             complement(277039..277422)
                     /locus_tag="COSY_0277"
                     /note="Similar to dioxygenase/lactoylglutathione lyase and
                     related lyases."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219130.1"
                     /db_xref="GI:148244436"
                     /db_xref="GeneID:5171961"
                     /translation="MNIRFSHIALRCNNINTVAIFFTEVIGLEKGFRPYFIFPGYWLY
                     SPENKQEAIIHILSKKAKFSIKTNNYNNLLDHIAFVRDDYPIFIKHINKLKINFYEKF
                     IPNLNTKQVFLKGPENITVEVNFII"
     misc_feature    complement(277054..277410)
                     /locus_tag="COSY_0277"
                     /note="This conserved domain belongs to a superfamily
                     including the bleomycin resistance protein, glyoxalase I,
                     and type I ring-cleaving dioxygenases; Region:
                     Glo_EDI_BRP_like_9; cd07245"
                     /db_xref="CDD:176669"
     misc_feature    complement(order(277054..277059,277153..277155,
                     277162..277167,277177..277200,277273..277275,
                     277285..277290,277297..277299,277339..277341,
                     277345..277350,277390..277392,277396..277410))
                     /locus_tag="COSY_0277"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:176669"
     misc_feature    complement(order(277057..277059,277195..277197,
                     277402..277404))
                     /locus_tag="COSY_0277"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176669"
     gene            complement(277597..278691)
                     /gene="prfB"
                     /locus_tag="COSY_0278"
                     /db_xref="GeneID:5172054"
     CDS             complement(277597..278691)
                     /gene="prfB"
                     /locus_tag="COSY_0278"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor RF-2"
                     /protein_id="YP_001219131.1"
                     /db_xref="GI:148244437"
                     /db_xref="GeneID:5172054"
                     /translation="MELSPTYQKIEDLKKCSGTLSIHLNLKKKQYRLEEILLEMEDPN
                     IWENPNQAQSLGREKSKLISICQTFEQVNAILEDAQELLNLAQTENDTETANGIINDL
                     DTAQSSIEKLEFKRMFSGDLDANSAYLDIQSGSGGTEAQDWAEMVLRMYLRWGEKHNF
                     KIKLMEVSAGEVAGIKSATIHFKGEYAFGWLRTEIGIHRLVRKSPFNANGKRHTSFCS
                     VFVSPEIDSDIDIDISPSDLRIDTYRASGAGGQHVNKTESAVRITHLPTNTVVQCQNG
                     RSQHANKNQAIKQLQSKLYKLEMQKRNTEKQSLEQSKSDISWGHQIRSYILDQSRVKD
                     LRTGIESSNTQNILEGNLDQFMKASLKSRL"
     misc_feature    complement(277600..278670)
                     /gene="prfB"
                     /locus_tag="COSY_0278"
                     /note="peptide chain release factor 2; Validated; Region:
                     prfB; PRK00578"
                     /db_xref="CDD:234799"
     misc_feature    complement(278110..278451)
                     /gene="prfB"
                     /locus_tag="COSY_0278"
                     /note="This domain is found in peptide chain release
                     factors; Region: PCRF; smart00937"
                     /db_xref="CDD:214923"
     misc_feature    complement(277684..277980)
                     /gene="prfB"
                     /locus_tag="COSY_0278"
                     /note="RF-1 domain; Region: RF-1; pfam00472"
                     /db_xref="CDD:201249"
     gene            complement(278763..279023)
                     /gene="rpsO"
                     /locus_tag="COSY_0279"
                     /db_xref="GeneID:5171809"
     CDS             complement(278763..279023)
                     /gene="rpsO"
                     /locus_tag="COSY_0279"
                     /note="primary rRNA binding protein; helps nucleate
                     assembly of 30S; binds directly to the 16S rRNA and an
                     intersubunit bridge to the 23S rRNA; autoregulates
                     translation through interactions with the mRNA leader
                     sequence"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="YP_001219132.1"
                     /db_xref="GI:148244438"
                     /db_xref="GeneID:5171809"
                     /translation="MSINIQEIIKEYQSKIGDTGSTNVQVALLTARIRHLTKHFKTHK
                     KDHHSRRGLLHLVSQRKKLLTYLRGNNKTAYSKLISHLELRK"
     misc_feature    complement(278778..279014)
                     /gene="rpsO"
                     /locus_tag="COSY_0279"
                     /note="Ribosomal protein S15 (prokaryotic)_S13
                     (eukaryotic) binds the central domain of 16S rRNA and is
                     required for assembly of the small ribosomal subunit and
                     for intersubunit association, thus representing a key
                     element in the assembly of the whole ribosome; Region:
                     Ribosomal_S15p_S13e; cd00353"
                     /db_xref="CDD:238213"
     misc_feature    complement(order(278826..278828,278838..278840,
                     278877..278882,278886..278891,278895..278897,
                     278907..278909,278916..278918,278928..278930,
                     278949..278951,278958..278960,279009..279011))
                     /gene="rpsO"
                     /locus_tag="COSY_0279"
                     /note="16S/18S rRNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238213"
     misc_feature    complement(order(278781..278783,278793..278795,
                     278913..278915,278922..278924,278931..278936,
                     278943..278945))
                     /gene="rpsO"
                     /locus_tag="COSY_0279"
                     /note="S13e-L30e interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:238213"
     misc_feature    complement(order(278778..278780,278841..278843,
                     278853..278855))
                     /gene="rpsO"
                     /locus_tag="COSY_0279"
                     /note="25S rRNA binding site [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238213"
     gene            complement(279078..279974)
                     /gene="htrB"
                     /locus_tag="COSY_0280"
                     /db_xref="GeneID:5172614"
     CDS             complement(279078..279974)
                     /gene="htrB"
                     /locus_tag="COSY_0280"
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A biosynthesis lauroyl acyltransferase"
                     /protein_id="YP_001219133.1"
                     /db_xref="GI:148244439"
                     /db_xref="GeneID:5172614"
                     /translation="MTKTKFFHPKFIPTWILIGLMKLSAKLPLKTQLTIGKIIGKNLY
                     SLLSRFRKIAFINLTKCFPEKNKDQVKKLVKQHFEALGIGLFETANCFYLNDKKLKQY
                     YHIKGAEILQNALDKKQNIILLVGHFTTMMLAGRILLQNFDFADVYRPQNNALFDNQM
                     QKIFTQHGSTMIKAKDTKTLIRVLKSGLPIWYTHDQDLGIKISIFAPFFNIQTATIKA
                     TEKLARIDNTVVIPLSFTRQYTTYTLEFSPILTNYPITNSQQNAQLTNQILQQQILKA
                     PEQYLWIHRRFKTKPNNESSFY"
     misc_feature    complement(279108..279968)
                     /gene="htrB"
                     /locus_tag="COSY_0280"
                     /note="Bacterial lipid A biosynthesis acyltransferase;
                     Region: Lip_A_acyltrans; pfam03279"
                     /db_xref="CDD:112109"
     misc_feature    complement(279111..279677)
                     /gene="htrB"
                     /locus_tag="COSY_0280"
                     /note="Lysophospholipid Acyltransferases (LPLATs) of
                     Glycerophospholipid Biosynthesis: LABLAT-like; Region:
                     LPLAT_LABLAT-like; cd07984"
                     /db_xref="CDD:153246"
     misc_feature    complement(order(279381..279389,279522..279533,
                     279579..279581,279585..279587,279594..279596))
                     /gene="htrB"
                     /locus_tag="COSY_0280"
                     /note="putative acyl-acceptor binding pocket; other site"
                     /db_xref="CDD:153246"
     gene            280007..281791
                     /gene="dnaG"
                     /locus_tag="COSY_0281"
                     /db_xref="GeneID:5172561"
     CDS             280007..281791
                     /gene="dnaG"
                     /locus_tag="COSY_0281"
                     /EC_number="2.7.7.-"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="YP_001219134.1"
                     /db_xref="GI:148244440"
                     /db_xref="GeneID:5172561"
                     /translation="MPFINADFKDDLPNRVNIVDIINQRVPLKKAGKDYKACCPFHHE
                     KTPSFIVSAEKQMYKCFGCGDGNGVIKFVMKFDNLGLVEAVETIASESGISVVYDKNI
                     KPIDTRLTRYLDLMQRVGQFYIQQLKQSLAKNKAVGYVKYRGISSQIAKRFELGFAPP
                     NSNLLFGFKQDSQDIADLKVMGLLCDDQYRSGKYYDLFKDRIMFPIHNNKGNIIAFGG
                     RSCNNNFKAKYFNSPETPIFSKSKELYGLYHMRKYSRSIDYILVVEGYMDVVSLHQAG
                     ISQVVATLGTVTTVEHLNILFRTTNTIIFCFDGDKAGEKAAWRALNITLPVIKAGITI
                     KFLFLPDKEDPDTLVKKESSQAFVKRIENAQFLSKFLFSHIKTEVDFNTIEGKTLFLE
                     RVSMLLRKINYKTYQHQLLEGLAGEVNQSIEQIESILERQDISTQSNTFSISKNYEEP
                     PMFNFYDSDEKYQVPMSVPLISNNSLIDQMIGLLLNYPSMVDKTVMLRVRKINNADIL
                     QKLANLVLLQEDITLETMVEQFPQKKQQLLNLYNKKRVLKNYDYKDEFLDALLKIEER
                     QKEKSALLITNEIEYTKNLQARKGKPKS"
     misc_feature    280016..281251
                     /gene="dnaG"
                     /locus_tag="COSY_0281"
                     /note="DNA primase, catalytic core; Region: dnaG;
                     TIGR01391"
                     /db_xref="CDD:233392"
     misc_feature    280016..280309
                     /gene="dnaG"
                     /locus_tag="COSY_0281"
                     /note="CHC2 zinc finger; Region: zf-CHC2; pfam01807"
                     /db_xref="CDD:110780"
     misc_feature    280370..280759
                     /gene="dnaG"
                     /locus_tag="COSY_0281"
                     /note="DNA primase catalytic core, N-terminal domain;
                     Region: Toprim_N; pfam08275"
                     /db_xref="CDD:219773"
     misc_feature    280778..281023
                     /gene="dnaG"
                     /locus_tag="COSY_0281"
                     /note="TOPRIM_DnaG_primases: The topoisomerase-primase
                     (TORPIM) nucleotidyl transferase/hydrolase domain found in
                     the active site regions of proteins similar to Escherichia
                     coli DnaG. Primases synthesize RNA primers for the
                     initiation of DNA replication. DnaG...; Region:
                     TOPRIM_DnaG_primases; cd03364"
                     /db_xref="CDD:173784"
     misc_feature    order(280796..280801,280808..280810,280928..280930,
                     280934..280936,280940..280942)
                     /gene="dnaG"
                     /locus_tag="COSY_0281"
                     /note="active site"
                     /db_xref="CDD:173784"
     misc_feature    order(280796..280798,280928..280930)
                     /gene="dnaG"
                     /locus_tag="COSY_0281"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:173784"
     misc_feature    order(280802..280807,280823..280828,280856..280858)
                     /gene="dnaG"
                     /locus_tag="COSY_0281"
                     /note="interdomain interaction site; other site"
                     /db_xref="CDD:173784"
     misc_feature    281105..281281
                     /gene="dnaG"
                     /locus_tag="COSY_0281"
                     /note="DnaB-helicase binding domain of primase; Region:
                     DnaB_bind; pfam10410"
                     /db_xref="CDD:220737"
     gene            complement(282020..282943)
                     /gene="mraW"
                     /locus_tag="COSY_0282"
                     /db_xref="GeneID:5172267"
     CDS             complement(282020..282943)
                     /gene="mraW"
                     /locus_tag="COSY_0282"
                     /note="cell envelope biogenesis"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-methyltransferase MraW"
                     /protein_id="YP_001219135.1"
                     /db_xref="GI:148244441"
                     /db_xref="GeneID:5172267"
                     /translation="MMPEYHQSVMFNESMYALNIKTDGIYIDATFGRGGHAQGILNRL
                     SKKGRLIAFDQDINAIEYANKNLVDNRLTLIHSAFSKMLSIITKQGLIGRIDGILIDL
                     GVSSPQLENAQRGFSFRVDGPLDMRMNQTTGMSATQWLKSANEEEIANVIYQFSNEKK
                     SRHIANKIKKYQKNHVLETTLELANIVSKVVKKQKNKHPATRTFQAIRIFINQELKQL
                     ISVLEQSKDILSKNGRLSIISFHSIEDRIVKRFIQKNSRQKTLPKGLPIIENEIEKTY
                     LKDLGKYLTSKAEIDNNKRARSAILRVASKN"
     misc_feature    complement(282023..282931)
                     /gene="mraW"
                     /locus_tag="COSY_0282"
                     /note="16S rRNA m(4)C1402 methyltranserfase; Provisional;
                     Region: PRK00050"
                     /db_xref="CDD:234597"
     misc_feature    complement(282023..282928)
                     /gene="mraW"
                     /locus_tag="COSY_0282"
                     /note="MraW methylase family; Region: Methyltransf_5;
                     cl17771"
                     /db_xref="CDD:248325"
     gene            complement(282933..283358)
                     /locus_tag="COSY_0283"
                     /db_xref="GeneID:5172058"
     CDS             complement(282933..283358)
                     /locus_tag="COSY_0283"
                     /note="Similar to cell envelope biogenesis protein MraZ"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219136.1"
                     /db_xref="GI:148244442"
                     /db_xref="GeneID:5172058"
                     /translation="MLKKVKMPTHHQTQIDKIYSIEMILSVHLDDEYWVLYPLKNWQV
                     WEEKISTLSLVNSHTKQLKRELINHTTNYELDKVVHILTPLTIKHYSHVDGKTIIGNQ
                     RHDFEVRNKNTWNKQFDYFDTISEINQNPIKLPNYHYDA"
     misc_feature    complement(283008..283349)
                     /locus_tag="COSY_0283"
                     /note="mraZ protein; Region: TIGR00242"
                     /db_xref="CDD:129345"
     gene            284122..286359
                     /gene="parC"
                     /locus_tag="COSY_0284"
                     /db_xref="GeneID:5172076"
     CDS             284122..286359
                     /gene="parC"
                     /locus_tag="COSY_0284"
                     /EC_number="5.99.1.-"
                     /note="decatenates newly replicated chromosomal DNA and
                     relaxes positive and negative DNA supercoiling"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="YP_001219137.1"
                     /db_xref="GI:148244443"
                     /db_xref="GeneID:5172076"
                     /translation="MNQINFEQQSIAQFSERAYLDYSMYVILDRALPFVGDGLKPVQR
                     RIIYAMSELGLKSTAKFKKSARTVGDVLGKFHPHGDSACYESMVLMAQKFSYRYPFID
                     GQGNWGAPDNPKSFAAMRYTESKLSRYADLLLLEINQGTVNWTDNFDGSLQEPKNLPA
                     QVPNLLLNGASGIAVGMATDVPPHNLIEVVSACIVLLDNPSIDLDDIMQTIQAPDYPT
                     DADIVSSSADLRQIYDTGYGSVKMRAVYQKEKGNIVIEALPFQVSGAKVISQIVVQMR
                     AKKLPLVDDIRDESDHENPTRIVIILHSNRFDVDALMLHLFATTELEKNYRVNMNVIG
                     LDGKPRVLPLIPMLKEWLSYRMQVVTNRLTCRFDKIIVRLHILKGLLIALLNINEVIA
                     VIREYDKPKLVLINHFKLNTIQAEAILELKLRHLAKLEEVRIRTEQQELVLERKQLEL
                     LLSSNSRLKSLIKKELKIIIKDFGDERRSNIKSNVNVAQAFSEDNLVLAEDVTVVLSN
                     KGWVRRVKGHDIDPTTLNYKAGDSYLTSVKGKSNKMVIFIDSTGRSYSLLAHSLSNSR
                     GQGEPLTGKLSPPLGAQFIDIIMGKTSQNILLSSDVGYGFIATFDDLLSSRQTGKVFL
                     SLSKGAQVMRVINVDDVDNQLVALATNRGRLLIFSISELPMLSKGKGNKLIQIPVNSA
                     KTRQEFVASVCILFETQQLRVNAGKHYLTIKFQDLNNYISNRACRGKLLPKGYQNVSS
                     IKVID"
     misc_feature    284134..286344
                     /gene="parC"
                     /locus_tag="COSY_0284"
                     /note="DNA topoisomerase IV subunit A; Validated; Region:
                     PRK05561"
                     /db_xref="CDD:235503"
     misc_feature    284206..285429
                     /gene="parC"
                     /locus_tag="COSY_0284"
                     /note="DNA Topoisomerase, subtype IIA; domain A&apos;;
                     bacterial DNA topoisomerase IV (C subunit, ParC),
                     bacterial DNA gyrases (A subunit, GyrA),mammalian DNA
                     toposiomerases II. DNA topoisomerases are essential
                     enzymes that regulate the conformational changes...;
                     Region: TOP4c; cd00187"
                     /db_xref="CDD:238111"
     misc_feature    order(284206..284286,284299..284448,284452..284457,
                     284461..284511,284515..284586,284593..284595)
                     /gene="parC"
                     /locus_tag="COSY_0284"
                     /note="CAP-like domain; other site"
                     /db_xref="CDD:238111"
     misc_feature    284482..284484
                     /gene="parC"
                     /locus_tag="COSY_0284"
                     /note="active site"
                     /db_xref="CDD:238111"
     misc_feature    order(285274..285282,285289..285300,285322..285327,
                     285367..285417)
                     /gene="parC"
                     /locus_tag="COSY_0284"
                     /note="primary dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238111"
     gene            286461..286838
                     /gene="ptpS"
                     /locus_tag="COSY_0285"
                     /db_xref="GeneID:5171882"
     CDS             286461..286838
                     /gene="ptpS"
                     /locus_tag="COSY_0285"
                     /EC_number="4.2.3.12"
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyltetrahydropterin synthase"
                     /protein_id="YP_001219138.1"
                     /db_xref="GI:148244444"
                     /db_xref="GeneID:5171882"
                     /translation="MFVLKIVTDFASAHSLRNYPGDCSRLHGHNWQVEVMVGSKELNN
                     NGIVIDFRDIKKQTKTVVKRLDHQYLNKIVPFDKLNPTSENLAKYFFDEVGRLININD
                     VKVKAVTIWETSRVSVTYSQGDL"
     misc_feature    286470..286820
                     /gene="ptpS"
                     /locus_tag="COSY_0285"
                     /note="6-pyruvoyl tetrahydropterin synthase; Region: PTPS;
                     pfam01242"
                     /db_xref="CDD:216384"
     misc_feature    order(286539..286541,286545..286547,286794..286796,
                     286812..286814)
                     /gene="ptpS"
                     /locus_tag="COSY_0285"
                     /note="active site"
                     /db_xref="CDD:238351"
     gene            286835..287629
                     /locus_tag="COSY_0286"
                     /db_xref="GeneID:5172473"
     CDS             286835..287629
                     /locus_tag="COSY_0286"
                     /note="similar protein in Methanocaldococcus converts GTP
                     to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the
                     first step in methanopterin biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="putative GTP cyclohydrolase"
                     /protein_id="YP_001219139.1"
                     /db_xref="GI:148244445"
                     /db_xref="GeneID:5172473"
                     /translation="MSATHLPDTQNSADTRHIIIDKVGIKDIIHPITYIDCDGNKMPT
                     IGMFTMTVSLPEHVKGTHMSRFIEILNENSCEFSAHNFDQIIDKVKEKLESDTAHITL
                     NFPFFRKKEAPSSGVKSMMDYQVTLYGTLNKGEVQVMIKVVVPVTSLCPCSKSISKYG
                     AHNQRSHITIKAKVSKGRTLHIEDLIDLAERKASCELYALLKRDDEKMVTERAYDNPA
                     FVEDLVRDIAVDLNADDKISYYCLESENFESIHNHSAYALIENLKC"
     misc_feature    286835..287626
                     /locus_tag="COSY_0286"
                     /note="putative GTP cyclohydrolase; Provisional; Region:
                     PRK13674"
                     /db_xref="CDD:237466"
     gene            287623..288690
                     /gene="aroG"
                     /locus_tag="COSY_0287"
                     /db_xref="GeneID:5172078"
     CDS             287623..288690
                     /gene="aroG"
                     /locus_tag="COSY_0287"
                     /EC_number="2.5.1.54"
                     /note="catalyzes the formation of
                     3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from
                     phosphoenolpyruvate and D-erythrose 4-phosphate,
                     phenylalanine sensitive"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-2-dehydro-3-deoxyheptonate aldolase"
                     /protein_id="YP_001219140.1"
                     /db_xref="GI:148244446"
                     /db_xref="GeneID:5172078"
                     /translation="MLKRILTKISNIRITKAESITPPIGFIKKYPVKKSQSNFIIDSR
                     KTIANIISGKDKRLLVVVGPCSIHDSKAARDYAYRLLEIKKELDRDLFIIMRVYFEKP
                     RTTIGWKGLIYDPDLNNSFDMEKGFDLARSLLLDLSKIGMPSATEYLDLITPQYISDL
                     ISWGAIGARTTESQTHRELASGLSCPVGFKNGTNGNIQIAIDAIISASSTHMFWSINK
                     KGVANRYTTMGNSNCHIILRGAADGPNYSKQSIENATKQLINDGLLGRVMIDFSHANS
                     KKNFKNQMLVGDEIAKQLSLGSNKIFGVMIESNINEGAQAVGELNSLEYGISITDSCL
                     GWQDTEKLLKILSLSVQARNT"
     misc_feature    287635..288681
                     /gene="aroG"
                     /locus_tag="COSY_0287"
                     /note="phospho-2-dehydro-3-deoxyheptonate aldolase;
                     Validated; Region: PRK09261"
                     /db_xref="CDD:236435"
     misc_feature    287764..288651
                     /gene="aroG"
                     /locus_tag="COSY_0287"
                     /note="DAHP synthetase I family; Region: DAHP_synth_1;
                     pfam00793"
                     /db_xref="CDD:216123"
     gene            288802..291387
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /db_xref="GeneID:5172217"
     CDS             288802..291387
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A GyrA"
                     /protein_id="YP_001219141.1"
                     /db_xref="GI:148244447"
                     /db_xref="GeneID:5172217"
                     /translation="MSKYTENSTNFESNFPIVTIESEMRNSYLEYAMSVIVGRALPDV
                     RDGLKPVHRRVLYAMDVLGNDYNKSYKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQP
                     FSMRNILIDGQGNFGSVDGDSAAAMRYTEIRMAKLSHELLQDLEKDTVDFVDNYDGSE
                     SEPSVLPARVPNLLANGSSGIAVGMATNIPPHNLNEVIEACLKTIENEDITIDELLEI
                     MPGPDFPTAGIINGTSGIRQAYETGKGKIYLRCVSHIEGEEKRSIIVTELPYQVNKAK
                     LIGKIAELVKDKRIDGITGLRDESDKDGMSMVIELRRGEVPEVILNNLYKLTEMQTVF
                     GINMVAIDKGIPKLMTLKDILEAFIAHRRDVVTRRSIFDLNKARNRVHLLEGLSVALY
                     NIDNIVELIKSAPSSTDARSILIAKTWRSSVIIELVGNRDMAMFKPENLPKELGLQMS
                     GDYQLSQKQVQAILDLKLHRLTGFEKDKIFDEFNELLERIKYLLDILQTPERLMQVIC
                     EELIDIQSNYGNARMTQILEHNIDLTLEDLIAQEERVVTLSHGGYVKAQSLSDYQAQC
                     RGGKGKSATKVKDEDFVDQLFIANSHDIVLCFSSFGKVYWLKVYDLPMASRISRGKPI
                     INLLPLEKKEIINAILPILKFDENHFVFMATSSGTCKKTALTNFSKPRKGGIIAIELR
                     NNDQLIGVEITSGEHDIMLFSANGKSIRFKESDVRIVGRTAIGVRGIKLVDGDKVVSL
                     IVTNQDSPVLTATEKGFGKRTHLNEYRVQSRGGSGVISIKTSDRNGKIIGAIQVTNED
                     EMMLISNKGILVRARAADVSIIGRNTQGVILINISKDEKLVSIAKVVETEDDKSESKS
                     KNYVK"
     misc_feature    288853..291345
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="DNA gyrase subunit A; Validated; Region: PRK05560"
                     /db_xref="CDD:235502"
     misc_feature    288910..290343
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="DNA Topoisomerase, subtype IIA; domain A&apos;;
                     bacterial DNA topoisomerase IV (C subunit, ParC),
                     bacterial DNA gyrases (A subunit, GyrA),mammalian DNA
                     toposiomerases II. DNA topoisomerases are essential
                     enzymes that regulate the conformational changes...;
                     Region: TOP4c; cd00187"
                     /db_xref="CDD:238111"
     misc_feature    order(288910..288993,289006..289155,289159..289215,
                     289219..289290,289297..289299)
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="CAP-like domain; other site"
                     /db_xref="CDD:238111"
     misc_feature    289186..289188
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="active site"
                     /db_xref="CDD:238111"
     misc_feature    order(289975..289983,289990..290001,290032..290037,
                     290182..290232)
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="primary dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238111"
     misc_feature    290434..290571
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:217832"
     misc_feature    290578..290727
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:217832"
     misc_feature    290746..290883
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:217832"
     misc_feature    290890..291033
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:217832"
     misc_feature    291046..291186
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:217832"
     misc_feature    291193..291333
                     /gene="gyrA"
                     /locus_tag="COSY_0288"
                     /note="DNA gyrase C-terminal domain, beta-propeller;
                     Region: DNA_gyraseA_C; pfam03989"
                     /db_xref="CDD:217832"
     gene            complement(291483..293054)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /db_xref="GeneID:5171805"
     CDS             complement(291483..293054)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor RF-3"
                     /protein_id="YP_001219142.1"
                     /db_xref="GI:148244448"
                     /db_xref="GeneID:5171805"
                     /translation="MISEISKRRTFAIISHPDAGKTTITEKLLLYAGVIKTAGSIKSR
                     KTKTHATSDWMNIEKERGISITSSIMQFEYDNHIINLLDTPGHEDFSEDTYRTLTAVD
                     SALMVIDIAKGVEIRTIKLMRVCRLRNTPILTFINKLDREGKEPIDLLDEIETMLNIE
                     CAPITWPIGMGKRLKGVIDLLEDKVYLYRTGKNSEVSKNITINGINNFQLDKILGKNI
                     AHKMREEVELIHGTTTPFDLDKFLAGKQTPIFFGSAISNFGIQNLLDSFIKYAPTPQN
                     RESNIRKVTPNETKLTGFIFKIQANMNPKHHDRLAFMRIVSGQYKKGTKVLQVATNKQ
                     IKISNAVTFMSHKRTLTEVAYAGDVIGIHNHGSISIGDTFTQGEKLTFQGIPNFAPEI
                     FKIAQLKDPLKAKAFKKGLNQLSEEGATQIFRPIVNSSQILGAVGVLQFDVVMHRLKY
                     EYNVHCQFKTINIVTARWITGDSKDIEQLKIKAGNNIAVDAKGMLTYLAPSNVNLQLT
                     IERYSNLVFSATREH"
     misc_feature    complement(291486..293045)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="peptide chain release factor 3; Provisional;
                     Region: prfC; PRK00741"
                     /db_xref="CDD:179105"
     misc_feature    complement(292233..293036)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="Release Factor 3 (RF3) protein involved in the
                     terminal step of translocation in bacteria; Region: RF3;
                     cd04169"
                     /db_xref="CDD:206732"
     misc_feature    complement(292989..293012)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="G1 box; other site"
                     /db_xref="CDD:206732"
     misc_feature    complement(order(292599..292601,292611..292613,
                     292719..292724,292791..292796,292848..292853,
                     292965..292970,292977..292979,292986..292991,
                     293001..293003,293007..293009))
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="putative GEF interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:206732"
     misc_feature    complement(order(292290..292298,292635..292637,
                     292641..292646,292986..293003))
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206732"
     misc_feature    complement(292851..292886)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206732"
     misc_feature    complement(292863..292865)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="G2 box; other site"
                     /db_xref="CDD:206732"
     misc_feature    complement(292797..292808)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="G3 box; other site"
                     /db_xref="CDD:206732"
     misc_feature    complement(292746..292802)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206732"
     misc_feature    complement(292635..292646)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="G4 box; other site"
                     /db_xref="CDD:206732"
     misc_feature    complement(292290..292298)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="G5 box; other site"
                     /db_xref="CDD:206732"
     misc_feature    complement(291924..292178)
                     /gene="prfC"
                     /locus_tag="COSY_0289"
                     /note="Translation_Factor_II_like: Elongation factor Tu
                     (EF-Tu) domain II-like proteins. Elongation factor Tu
                     consists of three structural domains, this family
                     represents the second domain. Domain II adopts a beta
                     barrel structure and is involved in binding to...; Region:
                     Translation_Factor_II_like; cl02787"
                     /db_xref="CDD:243185"
     gene            complement(293051..293497)
                     /locus_tag="COSY_0290"
                     /db_xref="GeneID:5171808"
     CDS             complement(293051..293497)
                     /locus_tag="COSY_0290"
                     /EC_number="3.5.4.12"
                     /note="dCMP deaminase"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxycytidylate deaminase"
                     /protein_id="YP_001219143.1"
                     /db_xref="GI:148244449"
                     /db_xref="GeneID:5171808"
                     /translation="MGILDKWDKRYLSLAKKVSTWSKDPSTQVGAVTVGRKKEVLSQG
                     FNGFPRGIHDTDERYHDREIKYKFVVHAEMNAIYNATYSGTSLDRATLYVYGLPICSE
                     CAKGIIQVGIKRVVIENSKELDNWNQSVRLSQEMFNETGIKLIIKI"
     misc_feature    complement(293087..293476)
                     /locus_tag="COSY_0290"
                     /note="Deoxycytidylate deaminase domain. Deoxycytidylate
                     deaminase catalyzes the deamination of dCMP to dUMP,
                     providing the nucleotide substrate for thymidylate
                     synthase. The enzyme binds Zn++, which is required for
                     catalytic activity. The activity of the...; Region:
                     deoxycytidylate_deaminase; cd01286"
                     /db_xref="CDD:238613"
     misc_feature    complement(order(293189..293191,293198..293203,
                     293279..293281,293285..293287,293357..293359))
                     /locus_tag="COSY_0290"
                     /note="catalytic motif [active]"
                     /db_xref="CDD:238613"
     misc_feature    complement(order(293189..293191,293198..293200,
                     293279..293281,293285..293287))
                     /locus_tag="COSY_0290"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:238613"
     gene            complement(293500..294585)
                     /gene="mraY"
                     /locus_tag="COSY_0291"
                     /db_xref="GeneID:5172185"
     CDS             complement(293500..294585)
                     /gene="mraY"
                     /locus_tag="COSY_0291"
                     /EC_number="2.7.8.13"
                     /note="First step of the lipid cycle reactions in the
                     biosynthesis of the cell wall peptidoglycan"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="YP_001219144.1"
                     /db_xref="GI:148244450"
                     /db_xref="GeneID:5172185"
                     /translation="MFLELINFITQFDTKFNVLNYLTIRALLAMLSALFIGLMLGRIF
                     IKRLQQCHINQVIRTDGPKSHLIKVGTPTMGGILILFAFIVSILIWGDWSNIYLWIII
                     VTSIIFSAIGFTDDYLKIKHKSSNGLSSSIKFLTQSLSAIVISTWIILISQKTTQPQL
                     LIPFFNDIILPLSVFDFLILSYFVIVGSSNAVNLTDGLDGLAIMSVILISGALAIFAY
                     FSGNYNFSNYLNMPYITGINELFIICAALIGSSLGFLWFNAYPAEIFMGDVGSLSLGA
                     ILAVIAILIRQEILLFIMGGVFVAETLSVIIQVGYYKLYKKRIFLMTPLHHHFEKQNI
                     SEPKIIVRFWIVTLILVLIGLASIKIH"
     misc_feature    complement(293506..294540)
                     /gene="mraY"
                     /locus_tag="COSY_0291"
                     /note="phospho-N-acetylmuramoyl-pentapeptide-transferase;
                     Provisional; Region: mraY; PRK00108"
                     /db_xref="CDD:234638"
     misc_feature    complement(293515..294405)
                     /gene="mraY"
                     /locus_tag="COSY_0291"
                     /note="Phospho-N-acetylmuramoyl-pentapeptide-transferase
                     (mraY) is an enzyme responsible for the formation of the
                     first lipid intermediate in the synthesis of bacterial
                     cell wall peptidoglycan. It catalyzes the formation of...;
                     Region: GT_MraY; cd06852"
                     /db_xref="CDD:133462"
     misc_feature    complement(294238..294243)
                     /gene="mraY"
                     /locus_tag="COSY_0291"
                     /note="Mg++ binding site [ion binding]; other site"
                     /db_xref="CDD:133462"
     misc_feature    complement(293782..293793)
                     /gene="mraY"
                     /locus_tag="COSY_0291"
                     /note="putative catalytic motif [active]"
                     /db_xref="CDD:133462"
     misc_feature    complement(order(293602..293616,293632..293634))
                     /gene="mraY"
                     /locus_tag="COSY_0291"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:133462"
     gene            295340..295573
                     /locus_tag="COSY_0292"
                     /db_xref="GeneID:5172056"
     CDS             295340..295573
                     /locus_tag="COSY_0292"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="YP_001219145.1"
                     /db_xref="GI:148244451"
                     /db_xref="GeneID:5172056"
                     /translation="MSLLITDECINCDVCEPECPNDAIYMGDEIYEIDGNKCTECKGH
                     FDEPQCVEVCPVDCCLPDPNRVETEEELLAKIK"
     misc_feature    295364..295510
                     /locus_tag="COSY_0292"
                     /note="4Fe-4S dicluster domain; Region: Fer4_7; pfam12838"
                     /db_xref="CDD:221801"
     gene            complement(295767..296882)
                     /locus_tag="COSY_0293"
                     /db_xref="GeneID:5172588"
     CDS             complement(295767..296882)
                     /locus_tag="COSY_0293"
                     /note="serine-pyruvate aminotransferase/archaeal aspartate
                     aminotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase, class V"
                     /protein_id="YP_001219146.1"
                     /db_xref="GI:148244452"
                     /db_xref="GeneID:5172588"
                     /translation="MQSFNPPVRTLMGSGPSDVHPRILSAMAKPTIGHLDPIFIAMMD
                     EIKEGLKTIFKTDNKLTMPISAPGSAGMEACFTNLVEPNDKVIICINGVFGMRMKENV
                     TRLGGKAIIVKDNWGEAISTDKLEHALKNNPNANIVAFVHAETSTGAQSDVKTLCKLA
                     HQYDCITIVDAVTSLGGTELYVDEWEIDAIYSGTQKCLSAMPGISLISFGKRAIQKLN
                     TRKTSVNSWFLDLNLIMNYWNGDSKRTYHHTAPVNMLYGLHESLVMILEEGIENSWVR
                     HKKNHELLKNGLEAMNINFLVNKKDRLPQLNSVLIPKGFDDEKIRSILLNDYNLEISA
                     GLGAYTGKIWRIGLMGYSSRKENIVLCLSALKEILRK"
     misc_feature    complement(295773..296855)
                     /locus_tag="COSY_0293"
                     /note="Alanine-glyoxylate aminotransferase (AGAT) family.
                     This family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to alanine-glyoxylate
                     aminotransferase (AGAT); Region: AGAT_like; cd06451"
                     /db_xref="CDD:99744"
     misc_feature    complement(order(295908..295910,296130..296141,
                     296199..296201,296277..296279,296298..296300,
                     296568..296573,296583..296585,296592..296594,
                     296664..296666,296682..296687,296775..296777,
                     296781..296783,296802..296804,296811..296813))
                     /locus_tag="COSY_0293"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99744"
     misc_feature    complement(order(296295..296300,296367..296369,
                     296373..296375,296448..296450,296601..296603,
                     296676..296684))
                     /locus_tag="COSY_0293"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99744"
     misc_feature    complement(296295..296297)
                     /locus_tag="COSY_0293"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99744"
     gene            296934..298364
                     /gene="glcD"
                     /locus_tag="COSY_0294"
                     /db_xref="GeneID:5171907"
     CDS             296934..298364
                     /gene="glcD"
                     /locus_tag="COSY_0294"
                     /EC_number="1.1.3.15"
                     /note="(S)-2-hydroxy-acid oxidase, FAD-linked subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcD"
                     /protein_id="YP_001219147.1"
                     /db_xref="GI:148244453"
                     /db_xref="GeneID:5171907"
                     /translation="MTIVNQLTRAFPKGIVLTSNENTRPFECDGLSVYRQKPLAVVLP
                     DNVMQIKQVLKICKINNIPIVTRGAGTGLSGGAMPLEKSIVLGLSKLNKVKLIDVENQ
                     LAVVEPGVRNIAISEAVAQYGLYYAPDPSSQIACTIGGNVSENSGGVHCLKYGLTVHN
                     VEAIRMLTIDGDELILSCQDDGLGLLALMNGSEGLLGVITEVTVKLTPNPAFVKMVMA
                     GFDSVRDCANAVTNIIKAGIIPAGLEMMDSFAIKAAEGFAQVGYPLDAKALLLCELDG
                     IQTQVQLELDNVLKILSGASTLKVSESEEERLNFWKGRKSAFSAVGTLSPDYYCMDGT
                     IPRRYLADMLEKIHKLSKKYQLRVANVFHAGDGNLHPLILYDANVTGELERTEEFGTE
                     ILKLSVDMGGTITGEHGVGVEKLNAMCHQFNTQELEIFHKIKQVFDEDSLFNPGKAVP
                     ELHRCAELGAMHIHRGELPYPELERF"
     misc_feature    296937..298361
                     /gene="glcD"
                     /locus_tag="COSY_0294"
                     /note="glycolate oxidase subunit GlcD; Provisional;
                     Region: PRK11230"
                     /db_xref="CDD:183043"
     misc_feature    297045..297464
                     /gene="glcD"
                     /locus_tag="COSY_0294"
                     /note="FAD binding domain; Region: FAD_binding_4;
                     pfam01565"
                     /db_xref="CDD:216574"
     gene            298364..298897
                     /locus_tag="COSY_0295"
                     /db_xref="GeneID:5172063"
     CDS             298364..298897
                     /locus_tag="COSY_0295"
                     /note="Similar to the N-terminal region of glycolate
                     oxidase subunit GlcE (352 aa) in Psychrobacter arcticus
                     273-4."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219148.1"
                     /db_xref="GI:148244454"
                     /db_xref="GeneID:5172063"
                     /translation="MDSRLQQLQTLVKESSSLHIKSTLLDYSGIVEYYAEELVISVKA
                     GTSIEQIKKQLKKNNQALSFYTDNDDISIGAAYAQGAQDLSDCVLGVKIIDGTGTYLN
                     FGGQVMKNVAGYDVARLLVGSKGKLALIMQISFKVMPAIYVNQLTPPIKRKNNSVLHK
                     HFEKKLKQVFDPRGIFN"
     misc_feature    <298406..298675
                     /locus_tag="COSY_0295"
                     /note="FAD binding domain; Region: FAD_binding_4;
                     pfam01565"
                     /db_xref="CDD:216574"
     gene            298897..300021
                     /gene="glcF"
                     /locus_tag="COSY_0296"
                     /db_xref="GeneID:5172570"
     CDS             298897..300021
                     /gene="glcF"
                     /locus_tag="COSY_0296"
                     /EC_number="1.1.3.15"
                     /note="(S)-2-hydroxy-acid oxidase, iron-sulfur subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase iron-sulfur subunit GlcF"
                     /protein_id="YP_001219149.1"
                     /db_xref="GI:148244455"
                     /db_xref="GeneID:5172570"
                     /translation="MQTIKISNMEANNIIRKCVHCGFCLATCPTYQLLGNELDSPRGR
                     IYLIKSVLENHHFSKKSIVHLDRCLTCRSCETTCPSGVEYVQLVNIGRKLVEQKRPLW
                     QKVYRYFIRQFLTTPILFNPIGFIFRHSQIKGKSIKPIIRIGTVLLLGGCVQPIIAPN
                     INHSIKNILAKLGYETIETPQKQCCGAIDQHLSVNHDALIQIKKNIDTWLKVKAEMII
                     VSASGCGLMIKDYVSMFEKLDPYYQKAQHIVNKTKDIAEFLADKNLNQLNLERVNIVY
                     HEPCTLQHGQQLGGLVSSILNSLGYQQTPVVDSHLCCGSAGTYSIFQPKLSQQLRANK
                     LKHLQIANPQMIVTANIGCLIHLQKKAKIPVKHWVELLDN"
     misc_feature    298924..300015
                     /gene="glcF"
                     /locus_tag="COSY_0296"
                     /note="glycolate oxidase iron-sulfur subunit; Provisional;
                     Region: glcF; PRK11274"
                     /db_xref="CDD:236890"
     misc_feature    <298939..>299163
                     /gene="glcF"
                     /locus_tag="COSY_0296"
                     /note="The HCP family of iron-sulfur proteins includes
                     hybrid cluster protein (HCP), acetyl-CoA synthase (ACS),
                     and carbon monoxide dehydrogenase (CODH), all of which
                     contain [Fe4-S4] metal clusters at their active sites.
                     These proteins have a conserved...; Region: HCP_like;
                     cl14655"
                     /db_xref="CDD:246686"
     misc_feature    299347..299583
                     /gene="glcF"
                     /locus_tag="COSY_0296"
                     /note="Cysteine-rich domain; Region: CCG; pfam02754"
                     /db_xref="CDD:202376"
     misc_feature    299716..299970
                     /gene="glcF"
                     /locus_tag="COSY_0296"
                     /note="Cysteine-rich domain; Region: CCG; pfam02754"
                     /db_xref="CDD:202376"
     gene            300047..301366
                     /gene="rumA"
                     /locus_tag="COSY_0298"
                     /db_xref="GeneID:5171997"
     CDS             300047..301366
                     /gene="rumA"
                     /locus_tag="COSY_0298"
                     /EC_number="2.1.1.-"
                     /note="23S rRNA (uracil-5-)-methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="YP_001219150.1"
                     /db_xref="GI:148244456"
                     /db_xref="GeneID:5171997"
                     /translation="MRRRRKLEHKTYKLNIESFSHEGRGIAHFEDKIIFVSDALPGEL
                     VIANRTFSCAKFEEADAKEILKPADNRMKPKCDVFGICGGCSFQNLSSEDQIQIKSRW
                     LKKVFARQAKVEPETWLKSLQFQSWGYRRKARLGIRYVAKKDKVLIGFRERKSSFITN
                     MSRCEVLHPSIGEHLEVLANCIERLSIKSSIPQFEVVISESGIALILRHLESLSVKDE
                     KILADCAQELNITFYTQSGGLDSVKPLDEPTILTYSHSNYNIIMEFLPTDFVQVNFKL
                     NQQMVSLAVELLELNESDKVIDLFCGLGNFTLPIARYAKYVVGIEGDLGLVERAKYNA
                     EKNSINNVDFYRSDLCKEVVGFEWFKGKTYNKALIDPSRSGAIEIVELLPKLGVTRLV
                     YVSCNPATLARDTLKLIKLGFTLETAGVIDMFPQTSHVESIALFVKR"
     misc_feature    300053..301363
                     /gene="rumA"
                     /locus_tag="COSY_0298"
                     /note="23S rRNA m(5)U1939 methyltransferase; Reviewed;
                     Region: rumA; PRK13168"
                     /db_xref="CDD:237291"
     misc_feature    300059..300232
                     /gene="rumA"
                     /locus_tag="COSY_0298"
                     /note="TRAM domain; Region: TRAM; cl01282"
                     /db_xref="CDD:242412"
     misc_feature    300929..>301162
                     /gene="rumA"
                     /locus_tag="COSY_0298"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(300941..300961,301007..301012,301085..301093,
                     301154..301156)
                     /gene="rumA"
                     /locus_tag="COSY_0298"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            301948..302094
                     /locus_tag="COSY_0299"
                     /pseudo
                     /db_xref="GeneID:5171860"
     misc_feature    301948..302094
                     /locus_tag="COSY_0299"
                     /note="Probable gene remnant. Similar to the central
                     region of beta-hexosaminidase (342 aa) in Shewanella sp.
                     MR-7."
                     /pseudo
     gene            302211..302492
                     /locus_tag="COSY_0300"
                     /db_xref="GeneID:5171817"
     CDS             302211..302492
                     /locus_tag="COSY_0300"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219151.1"
                     /db_xref="GI:148244457"
                     /db_xref="GeneID:5171817"
                     /translation="MNNDNKQRFEIRFLAVVRKTLIAVAKDTITRPGLKHPLSKVTQE
                     MITDCLDIVTSRQIAIEKSSGIHTNMKPVYTDKQTVQSFSIDDLKKTLN"
     gene            complement(302807..304960)
                     /gene="uvrD"
                     /locus_tag="COSY_0301"
                     /db_xref="GeneID:5171952"
     CDS             complement(302807..304960)
                     /gene="uvrD"
                     /locus_tag="COSY_0301"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II / ATP-dependent DNA helicase
                     PcrA"
                     /protein_id="YP_001219152.1"
                     /db_xref="GI:148244458"
                     /db_xref="GeneID:5171952"
                     /translation="MNLSEITNGLNDKQCQSVTLNNEKNALILAGAGSGKTKVLIHRI
                     AYLITQKDIHIDAILAVTFTNKAATEMCERLSKLLRHPITSMWTGTFHSLAHRLLRTH
                     YEQAQLTYNFQILDAQDQFRIIKNLMKENNIDESKFPIKKVQQFINNQKNKGIHLHDI
                     DSSYNYFIKKSLKVFELYEVHCKTNELIDFAELLIRSYELLKNNVNLLNHYKNRFKHI
                     LIDEFQDTNMIQYKWIKLLFSGNNKVFCVGDDDQSIYGWRGANIENITKLCTDFVPIK
                     TIRLEQNYRSTNNILTASNALIAHNTSRMGKSLWTNAIDGELIDMYEAQTEIDEADYV
                     VSSIQKLITNGVLPNDCAILYRLNTQSRIFEEVLIKYNIPYIIYGGLKFFERAEIKHA
                     LSYLRLIENSDDNLAFERVVNFPTRGIGNTTINKIRIFAQNNHVSLFQATIQVSSTLS
                     TRTTNALNGFTNLIEKMKDDTKNLNLSEKIVNLLNMSGLMAHYSNDKTSNKKENLEEL
                     ITAAKQYKQNNDMNEIIGFISLASIDSGGNTNTLTNQNVQLMTMHSAKGLEFPYVFLS
                     GMEEGLSPYRQSKNKPHLIDEERRLCYVGMTRAMKKLSLSYTMKRFLHGHFLYADPSR
                     FLNEIPDEYLNKIKVKFDITIKNYNNNNIFNQSITPKSDNQLHIGALVNHPKFGLGTV
                     LNFEGQGDSSRIQIKFKQAGSIKWLISSYANLEFI"
     misc_feature    complement(302816..304960)
                     /gene="uvrD"
                     /locus_tag="COSY_0301"
                     /note="DNA-dependent helicase II; Provisional; Region:
                     uvrD; PRK11773"
                     /db_xref="CDD:236976"
     misc_feature    complement(304676..304882)
                     /gene="uvrD"
                     /locus_tag="COSY_0301"
                     /note="Part of AAA domain; Region: AAA_19; pfam13245"
                     /db_xref="CDD:222005"
     misc_feature    complement(303146..>303304)
                     /gene="uvrD"
                     /locus_tag="COSY_0301"
                     /note="Family description; Region: UvrD_C_2; pfam13538"
                     /db_xref="CDD:222209"
     gene            305080..305265
                     /locus_tag="COSY_0302"
                     /db_xref="GeneID:5172066"
     CDS             305080..305265
                     /locus_tag="COSY_0302"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219153.1"
                     /db_xref="GI:148244459"
                     /db_xref="GeneID:5172066"
                     /translation="MTYYAGVKKMEEMGVNDNYIQGWVAGFLNNPEIEEQRITNEWKS
                     GYEDGKEHTDVNFINFC"
     gene            305270..306214
                     /gene="kamA"
                     /locus_tag="COSY_0303"
                     /db_xref="GeneID:5171999"
     CDS             305270..306214
                     /gene="kamA"
                     /locus_tag="COSY_0303"
                     /EC_number="5.4.3.2"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine 2,3-aminomutase"
                     /protein_id="YP_001219154.1"
                     /db_xref="GI:148244460"
                     /db_xref="GeneID:5171999"
                     /translation="MENNWQYYARYTLKGANKSNVFFKTKMFKDCTFPIKIPMEFARL
                     IDKRNKDDPLLKQVITPKNLSKSTNFSLSPLEDEKYSPVAGLIHKYPNRVLLIASQVC
                     AIHCQFCFRQNFNYVEHDAISNWVEIQNYIINDVKINEVILSGGDPLSLSDDKLSTLI
                     DNIAHIEHIKTLRVHTRNAVVEPSRITRKLVEIFNQSRLNIVIVLHINHAQELSVQFA
                     QKIIELTRVTLLSQSVLLRGVNDSIEVLTELCLSLFDLGILPYYLHMLDKVQGAQDFL
                     VKDDYAIQLHQQLKSNLSGYLVPKLVRDSSSYSKDWLF"
     misc_feature    305555..305995
                     /gene="kamA"
                     /locus_tag="COSY_0303"
                     /note="Radical SAM superfamily; Region: Radical_SAM;
                     pfam04055"
                     /db_xref="CDD:217866"
     misc_feature    305573..>305872
                     /gene="kamA"
                     /locus_tag="COSY_0303"
                     /note="Radical SAM superfamily. Enzymes of this family
                     generate radicals by combining a 4Fe-4S cluster and
                     S-adenosylmethionine (SAM) in close proximity. They are
                     characterized by a conserved CxxxCxxC motif, which
                     coordinates the conserved iron-sulfur cluster; Region:
                     Radical_SAM; cd01335"
                     /db_xref="CDD:100105"
     misc_feature    order(305573..305575,305579..305581,305585..305587,
                     305591..305599,305699..305701,305705..305710,
                     305792..305800)
                     /gene="kamA"
                     /locus_tag="COSY_0303"
                     /note="FeS/SAM binding site; other site"
                     /db_xref="CDD:100105"
     gene            complement(306206..306781)
                     /locus_tag="COSY_0304"
                     /db_xref="GeneID:5172718"
     CDS             complement(306206..306781)
                     /locus_tag="COSY_0304"
                     /note="AhpC/TSA family protein/cytochrome c biogenesis
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="YP_001219155.1"
                     /db_xref="GI:148244461"
                     /db_xref="GeneID:5172718"
                     /translation="MTKNSIIPTNYLFQLSNKIIKFSFICLLFVTLNIAQANNINDIV
                     KSANDIWREERKIKVPNFYLTDLDDNIYTNKSTKGKYLVINFWATWCPPCLKEIPTFI
                     KFYEKNKDRIIILGLNYEQADKIAIMEFTDTFMVNYPIVLFNDKNRTQFKKFGEIVGM
                     PTTYIYGPNGNLVDYQIGEMNMKDLEKAISK"
     misc_feature    complement(306248..306601)
                     /locus_tag="COSY_0304"
                     /note="TlpA-like family; composed of  TlpA, ResA, DsbE and
                     similar proteins. TlpA, ResA and DsbE are bacterial
                     protein disulfide reductases with important roles in
                     cytochrome maturation. They are membrane-anchored proteins
                     with a soluble TRX domain containing a...; Region:
                     TlpA_like_family; cd02966"
                     /db_xref="CDD:239264"
     misc_feature    complement(306269..306547)
                     /locus_tag="COSY_0304"
                     /note="Thioredoxin-like; Region: Thioredoxin_8; pfam13905"
                     /db_xref="CDD:222448"
     misc_feature    complement(order(306500..306502,306509..306511))
                     /locus_tag="COSY_0304"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239264"
     gene            306794..307141
                     /gene="arsC"
                     /locus_tag="COSY_0305"
                     /db_xref="GeneID:5171992"
     CDS             306794..307141
                     /gene="arsC"
                     /locus_tag="COSY_0305"
                     /EC_number="1.20.4.1"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="YP_001219156.1"
                     /db_xref="GI:148244462"
                     /db_xref="GeneID:5171992"
                     /translation="MSIIIYHNPKCSKSRTTLAILEQKNVDFEIIKYLENPPTINELK
                     QLLIDLKLEARLLIRKGELEYKEKGLDDKHLTEDQLISAMVKTPKLIERPIVRTSKGV
                     VIGRPPENIFSIL"
     misc_feature    306800..307135
                     /gene="arsC"
                     /locus_tag="COSY_0305"
                     /note="Arsenate Reductase (ArsC) family, ArsC subfamily;
                     arsenic reductases similar to that encoded by arsC on the
                     R733 plasmid of Escherichia coli. E. coli ArsC catalyzes
                     the reduction of arsenate [As(V)] to arsenite [As(III)],
                     the first step in the...; Region: ArsC_ArsC; cd03034"
                     /db_xref="CDD:239332"
     misc_feature    306809..307126
                     /gene="arsC"
                     /locus_tag="COSY_0305"
                     /note="ArsC family; Region: ArsC; pfam03960"
                     /db_xref="CDD:202832"
     misc_feature    order(306824..306826,306968..306970,307070..307072,
                     307109..307111)
                     /gene="arsC"
                     /locus_tag="COSY_0305"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239332"
     gene            complement(307171..307830)
                     /gene="gst"
                     /locus_tag="COSY_0306"
                     /db_xref="GeneID:5172251"
     CDS             complement(307171..307830)
                     /gene="gst"
                     /locus_tag="COSY_0306"
                     /EC_number="2.5.1.18"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="YP_001219157.1"
                     /db_xref="GI:148244463"
                     /db_xref="GeneID:5172251"
                     /translation="MKLELISFKLCPFAQCAIILLNKQELAFELNYINSINLPNWFKQ
                     ISPTGKVPLLKANDKIIFESSVITEFINDISKTNLHPSDPIKKAKNRSWIHFSSTLFD
                     DLFDVITGDKEKFYTSKKSLFDKLSKIEAVKNNSQFFNGDDFSIIDATFAPIFMRLSW
                     INKFTNNTLSFDRLTNIKAWSQDLLQVDIVKNSVVKNLDDVYYSNIETRKGHISTLFI
                     D"
     misc_feature    complement(307291..307824)
                     /gene="gst"
                     /locus_tag="COSY_0306"
                     /note="Glutathione S-transferase [Posttranslational
                     modification, protein turnover, chaperones]; Region: Gst;
                     COG0625"
                     /db_xref="CDD:223698"
     misc_feature    complement(307612..307818)
                     /gene="gst"
                     /locus_tag="COSY_0306"
                     /note="Glutathione S-transferase, N-terminal domain;
                     Region: GST_N_3; pfam13417"
                     /db_xref="CDD:205595"
     misc_feature    complement(307291..307560)
                     /gene="gst"
                     /locus_tag="COSY_0306"
                     /note="C-terminal, alpha helical domain of the Glutathione
                     S-transferase family; Region: GST_C_family; cd00299"
                     /db_xref="CDD:198286"
     misc_feature    complement(order(307360..307362,307372..307374,
                     307381..307386,307393..307395,307537..307539,
                     307558..307560))
                     /gene="gst"
                     /locus_tag="COSY_0306"
                     /note="N-terminal domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:198286"
     misc_feature    complement(order(307447..307449,307534..307536,
                     307543..307548,307555..307560))
                     /gene="gst"
                     /locus_tag="COSY_0306"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:198286"
     misc_feature    complement(order(307360..307362,307369..307371,
                     307522..307527,307537..307539))
                     /gene="gst"
                     /locus_tag="COSY_0306"
                     /note="substrate binding pocket (H-site) [chemical
                     binding]; other site"
                     /db_xref="CDD:198286"
     gene            complement(308015..308647)
                     /gene="nadD"
                     /locus_tag="COSY_0307"
                     /db_xref="GeneID:5171840"
     CDS             complement(308015..308647)
                     /gene="nadD"
                     /locus_tag="COSY_0307"
                     /EC_number="2.7.7.18"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="YP_001219158.1"
                     /db_xref="GI:148244464"
                     /db_xref="GeneID:5171840"
                     /translation="MQKSLHSKLFKIIGFFGGSFDPIHYGHLKNAAQLKDKLRLSKLF
                     LMPCDKPVHKKQLNFSINQRIDMLHLAIKEFNTLSIDTREIKQNKNSYTINSLKYIQS
                     KYQNNSICLIMGMDSFNTLSSWEECQNFYQYCHLVIMSRPGILTYQKKYGFRLTNIIN
                     DLTKQKTGFIFFANNQMLNISSSTIQGKIKSQKNLSGLLPDSIINYINAL"
     misc_feature    complement(308024..308617)
                     /gene="nadD"
                     /locus_tag="COSY_0307"
                     /note="nicotinic acid mononucleotide adenylyltransferase;
                     Provisional; Region: nadD; PRK00071"
                     /db_xref="CDD:234611"
     misc_feature    complement(308024..308611)
                     /gene="nadD"
                     /locus_tag="COSY_0307"
                     /note="Nicotinamide/nicotinate mononucleotide
                     adenylyltransferase; Region: NMNAT; cd02165"
                     /db_xref="CDD:185680"
     misc_feature    complement(order(308108..308110,308225..308230,
                     308273..308278,308297..308302,308306..308311,
                     308315..308317,308369..308377,308495..308497,
                     308558..308560,308567..308572,308576..308578,
                     308588..308602))
                     /gene="nadD"
                     /locus_tag="COSY_0307"
                     /note="active site"
                     /db_xref="CDD:185680"
     misc_feature    complement(308567..308578)
                     /gene="nadD"
                     /locus_tag="COSY_0307"
                     /note="(T/H)XGH motif; other site"
                     /db_xref="CDD:185680"
     gene            complement(308651..309373)
                     /locus_tag="COSY_0308"
                     /db_xref="GeneID:5172517"
     CDS             complement(308651..309373)
                     /locus_tag="COSY_0308"
                     /note="Similar to glyoxalase II (hydroxyacylglutathione
                     hydrolase) GloB."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219159.1"
                     /db_xref="GI:148244465"
                     /db_xref="GeneID:5172517"
                     /translation="MNIQTFKEKTYTLEILYHIGVLEDSIHFIFDHSTKTCAIVDPAW
                     NAPLFIQRIHDKGYTLTDIWLTHWHFDHTNAVDEIVEATGAKITVGVNEIHYLKINNL
                     PDTVENNDTIFIGNTTAKIINTPGHSAGGICYLLDRHIIAGDTLFVYGAGHCSLPGGN
                     IKELFNSMQKLKYIDNDVMLHCGHDYGSKINTTMGEQKQGNAFLLLDNEDDFVNYVNS
                     MQQGKIPYPTGPLTQAEIKDML"
     misc_feature    complement(<308816..309319)
                     /locus_tag="COSY_0308"
                     /note="Metallo-beta-lactamase superfamily; Region:
                     Lactamase_B; cl00446"
                     /db_xref="CDD:241867"
     gene            309468..309543
                     /locus_tag="COSY_t11"
                     /db_xref="GeneID:5329732"
     tRNA            309468..309543
                     /locus_tag="COSY_t11"
                     /product="tRNA-Ala"
                     /db_xref="GeneID:5329732"
     gene            309560..309634
                     /locus_tag="COSY_t12"
                     /db_xref="GeneID:5329759"
     tRNA            309560..309634
                     /locus_tag="COSY_t12"
                     /product="tRNA-Glu"
                     /db_xref="GeneID:5329759"
     gene            complement(309885..310214)
                     /locus_tag="COSY_0311"
                     /db_xref="GeneID:5171828"
     CDS             complement(309885..310214)
                     /locus_tag="COSY_0311"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219160.1"
                     /db_xref="GI:148244466"
                     /db_xref="GeneID:5171828"
                     /translation="MDDSQEIQKVFFKKLIDGDFGLAKTYWFYGVLVGLIGQIIMLGV
                     EMSESIALVIITILAALTYNVCQMIGTWNAANRYTGSKIWTVLAKITVALGVIAITFT
                     IIILTNL"
     gene            310955..311899
                     /gene="rluD"
                     /locus_tag="COSY_0312"
                     /db_xref="GeneID:5171976"
     CDS             310955..311899
                     /gene="rluD"
                     /locus_tag="COSY_0312"
                     /EC_number="4.2.1.70"
                     /note="23S rRNA pseudouridine synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal large subunit pseudouridine synthase
                     D"
                     /protein_id="YP_001219161.1"
                     /db_xref="GI:148244467"
                     /db_xref="GeneID:5171976"
                     /translation="MSLLSIIIPNRFINQRVDVAMAQMLPNYSRTKITYWIKSGNALI
                     HRKTFKPKEKVLGGEMVNLLIKTKKANSWLAEDAAIDVVYEDSEIIIVNKPVGLVTHP
                     GASNWTGTLANALLHYDSSLANLDRAGIVHRLDKNTSGLMVVARSEYAQKYLTKQLQT
                     HSISREYSAIVYGYMISGGSVDAPIGRDPKDRIKQAVVKDGKYALTHYRIIERFTHHT
                     HVKAILETGRTHQIRVHLSFIGHPLIADPIYGGKVYFPKKADKQLTKALKNFNRQTLH
                     AKKLTLTHPISGELMSWKMPLPQDMQDLLQILAKFDSC"
     misc_feature    310964..311878
                     /gene="rluD"
                     /locus_tag="COSY_0312"
                     /note="23S rRNA pseudouridine synthase D; Provisional;
                     Region: rluD; PRK11180"
                     /db_xref="CDD:183020"
     misc_feature    310997..311233
                     /gene="rluD"
                     /locus_tag="COSY_0312"
                     /note="S4/Hsp/ tRNA synthetase RNA-binding domain; The
                     domain surface is populated by conserved, charged residues
                     that define a likely RNA-binding site;  Found in stress
                     proteins, ribosomal proteins and tRNA synthetases; This
                     may imply a hitherto unrecognized...; Region: S4; cl09940"
                     /db_xref="CDD:245212"
     misc_feature    order(311000..311002,311036..311041,311045..311050,
                     311054..311059,311066..311071,311075..311077,
                     311093..311116,311120..311122)
                     /gene="rluD"
                     /locus_tag="COSY_0312"
                     /note="RNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238095"
     misc_feature    311219..311800
                     /gene="rluD"
                     /locus_tag="COSY_0312"
                     /note="Pseudouridine synthase, RsuA/RluD family; Region:
                     PseudoU_synth_RluCD_like; cd02869"
                     /db_xref="CDD:211346"
     misc_feature    order(311348..311359,311651..311653)
                     /gene="rluD"
                     /locus_tag="COSY_0312"
                     /note="active site"
                     /db_xref="CDD:211346"
     gene            complement(311951..312367)
                     /locus_tag="COSY_0313"
                     /db_xref="GeneID:5172576"
     CDS             complement(311951..312367)
                     /locus_tag="COSY_0313"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219162.1"
                     /db_xref="GI:148244468"
                     /db_xref="GeneID:5172576"
                     /translation="MSDLDTPQEIFNTNCSTNSEPFALQNLGKYMIPEFSENCIVIID
                     PSMKIHNHAYTVVRYDMEIYFRQYIERGSRKFLICLNTQYDDIELKGEFTVVGCVIQQ
                     KQRKQKPLHYYHLNTSTKEMSFSASGTLKNNKEKQL"
     misc_feature    complement(312068..312304)
                     /locus_tag="COSY_0313"
                     /note="Peptidase S24 LexA-like proteins are involved in
                     the SOS response leading to the repair of single-stranded
                     DNA within the bacterial cell. This family includes: the
                     lambda repressor CI/C2 family and related bacterial
                     prophage repressor proteins; LexA (EC...; Region:
                     S24_LexA-like; cd06529"
                     /db_xref="CDD:119397"
     misc_feature    complement(order(312170..312172,312278..312280))
                     /locus_tag="COSY_0313"
                     /note="Catalytic site [active]"
                     /db_xref="CDD:119397"
     gene            complement(312355..313164)
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /db_xref="GeneID:5172252"
     CDS             complement(312355..313164)
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /EC_number="3.2.2.23"
                     /note="Involved in base excision repair of DNA damaged by
                     oxidation or by mutagenic agents. Acts as DNA glycosylase
                     that recognizes and removes damaged bases"
                     /codon_start=1
                     /transl_table=11
                     /product="formamidopyrimidine-DNA glycosylase"
                     /protein_id="YP_001219163.1"
                     /db_xref="GI:148244469"
                     /db_xref="GeneID:5172252"
                     /translation="MPELPEIETIKRGLTSLIINQKVNKAILHRENLRWVIPKHLSTT
                     LTNQLISTIDRRGKYLLIKFKVGTLIIHLGMSGSIKVVNTNTPLLKHEHFELQLKNGT
                     SMRLKDPRRFGAVLFSKDGSHKLLDSLGVEPLKTSFYDGYLYQKSRNKQQNIKAFIMD
                     NKIVVGVGNIYACESLFMAGINPKLKAGSISKTRYNVLTQCIKNILTQAIEAGGTTLQ
                     DFVQVNGNPGYFTQNLSVYGCKNKKCYRCKGIIIKFVQNQRSTFYCKKCQT"
     misc_feature    complement(312361..313164)
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="formamidopyrimidine/5-formyluracil/
                     5-hydroxymethyluracil DNA glycosylase; Validated; Region:
                     PRK01103"
                     /db_xref="CDD:234899"
     misc_feature    complement(312814..313161)
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="N-terminal domain of Escherichia coli Fpg1/MutM and
                     related bacterial DNA glycosylases; Region: EcFpg-like_N;
                     cd08966"
                     /db_xref="CDD:176800"
     misc_feature    complement(order(312829..312840,312892..312897,
                     312937..312945,312949..312951,312991..312993,
                     313156..313161))
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:176800"
     misc_feature    complement(313159..313161)
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:176800"
     misc_feature    complement(order(312937..312939,312991..313002,
                     313129..313131,313138..313143,313147..313158))
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="H2TH interface [polypeptide binding]; other site"
                     /db_xref="CDD:176800"
     misc_feature    complement(order(312991..312993,313156..313158))
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="putative catalytic residues [active]"
                     /db_xref="CDD:176800"
     misc_feature    complement(312949..312951)
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="turnover-facilitating residue; other site"
                     /db_xref="CDD:176800"
     misc_feature    complement(order(312829..312831,312835..312837,
                     312940..312942))
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="intercalation triad [nucleotide binding]; other
                     site"
                     /db_xref="CDD:176800"
     misc_feature    complement(312937..312939)
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="8OG recognition residue [nucleotide binding]; other
                     site"
                     /db_xref="CDD:176800"
     misc_feature    complement(order(312832..312834,312892..312894))
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="putative reading head residues; other site"
                     /db_xref="CDD:176800"
     misc_feature    complement(312502..312780)
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="Formamidopyrimidine-DNA glycosylase H2TH domain;
                     Region: H2TH; pfam06831"
                     /db_xref="CDD:115485"
     misc_feature    complement(312361..312441)
                     /gene="mutM"
                     /locus_tag="COSY_0314"
                     /note="Zinc finger found in FPG and IleRS; Region:
                     zf-FPG_IleRS; pfam06827"
                     /db_xref="CDD:203527"
     gene            313220..313816
                     /locus_tag="COSY_0315"
                     /db_xref="GeneID:5172022"
     CDS             313220..313816
                     /locus_tag="COSY_0315"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219164.1"
                     /db_xref="GI:148244470"
                     /db_xref="GeneID:5172022"
                     /translation="MEKNMFDRINLVQCKILLGFILSVIIFFSFNYKIVEAQNLTHYG
                     LIVWLHVLAGIVWIGLLYYFNFVQVPAMGQALSDTNGPGPAAIGKYIAPRALLWFRMS
                     AITTWILGLVLLATKDAILSAFMLEPTFQIIGIGAWMGTIMVFNVWFIIWPNQQKILG
                     VKSASDTAIVIAKKNAALASSVNVILSIPMLLTMLAWH"
     misc_feature    313352..>313564
                     /locus_tag="COSY_0315"
                     /note="Protein of unknown function (DUF989); Region:
                     DUF989; pfam06181"
                     /db_xref="CDD:218928"
     misc_feature    <313616..313813
                     /locus_tag="COSY_0315"
                     /note="Protein of unknown function (DUF989); Region:
                     DUF989; pfam06181"
                     /db_xref="CDD:218928"
     gene            314128..315183
                     /locus_tag="COSY_0316"
                     /db_xref="GeneID:5172615"
     CDS             314128..315183
                     /locus_tag="COSY_0316"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219165.1"
                     /db_xref="GI:148244471"
                     /db_xref="GeneID:5172615"
                     /translation="MRKQLLIAAVAATMSVAATADISITGDAYIDFAKQKIGAADTAN
                     TNHDSQRTRLKVVGSAGGDAKVTAVVRNDGATRANDNDIDSSKKGLHMDSLYLTTKVG
                     PVNVKVGDYWGTIGLGARSLDAARSNALSASTKVGDWKLGLFTADGSSDDGSDTTNVS
                     ASGLLGPVSVGLVHNPGGFTNFTAKTTFNGILFAVDKWNDKRRNIIHNDTTLIHIGGK
                     VNHFTWDLAQIKNDQASDMTDTSIVTNGKFAPLGSMLIGRSARGGTATAVADVSHFSE
                     ILGVAVSTKLAGNTVKAIYTKNTMFGDDKVTGTELIVSRPLGGTTLTANIAKLSDVNT
                     IVNGNATNTGLRLDVKF"
     gene            315362..316033
                     /locus_tag="COSY_0317"
                     /db_xref="GeneID:5172592"
     CDS             315362..316033
                     /locus_tag="COSY_0317"
                     /note="Similar to aminomethyltransferase related to GcvT."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219166.1"
                     /db_xref="GI:148244472"
                     /db_xref="GeneID:5172592"
                     /translation="MKVRITLKVSGVDAQSFLQGQLSNDIVSIGENEWQLNAYCQHQG
                     KVIALFWVTKYKNDFYLNFPKSLQDKIFKHLHIFVLMSDVEIVQTSFNTYPPIDVMKH
                     PEVYLITSEKFVPQELNLDINEVGVNFSKGCYPGQEIVARLHYLGKPKRRMRLFECEQ
                     ILKVGDKLIALDSKSVKASGIVVRCIKLYGKLLYLATIEVKYQDSDIIANNSNDAKFT
                     RIKND"
     misc_feature    315380..316003
                     /locus_tag="COSY_0317"
                     /note="Predicted aminomethyltransferase related to GcvT
                     [General function prediction only]; Region: COG0354"
                     /db_xref="CDD:223431"
     misc_feature    315668..315835
                     /locus_tag="COSY_0317"
                     /note="folate-binding protein YgfZ; Region:
                     ygfZ_signature; TIGR03317"
                     /db_xref="CDD:234167"
     gene            315999..317396
                     /gene="nhaD"
                     /locus_tag="COSY_0318"
                     /db_xref="GeneID:5172599"
     CDS             315999..317396
                     /gene="nhaD"
                     /locus_tag="COSY_0318"
                     /note="NhaD Na+:H+ antiporter family"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+:H+ antiporter NhaD"
                     /protein_id="YP_001219167.1"
                     /db_xref="GI:148244473"
                     /db_xref="GeneID:5172599"
                     /translation="MTPNSQGLKMIKLCTLLFMLLSMDASATSEPPLDLTIHWVGYTS
                     LILFVLAYILVMVEEFTHFRKSKPVILVAGVIWGLIGWMYTSQGLPYFAEVALRHNIL
                     EYAELFLFLLVAMTYIEAMRERHVFEALKVWLINKGLTFRQLFWLTGFLAFFISPIAD
                     NLTTALIMGAVVLAVGAGNPRFITISFINIVVAANAGGVFSPFGDITTLMVWQNGIVG
                     FAQFFSLFVPSLINFVVPASIMHFSIKNEMTTNNQSKVNIKLGGIIIIILFIITIITA
                     VSFHNFLHLPPAMGMMTGLSYLMIAAYFIRQSECKLQQEGFDVFRKVANAEWDTLLFF
                     FGVIVSVGGLGFIGYLTLASEAMYLSLGATYANILIGVLSAIVDNIPVMFAVLTMNPD
                     MSLGQWLLVTLTTGVGGSLFSIGSAAGVALMGQSNGLYTFLSHLRWTGVIVLGYGLSI
                     GAHILMNAALFDVPV"
     misc_feature    316113..317363
                     /gene="nhaD"
                     /locus_tag="COSY_0318"
                     /note="Na+/H+ antiporter NhaD and related arsenite
                     permeases [Inorganic ion transport and metabolism];
                     Region: ArsB; COG1055"
                     /db_xref="CDD:223983"
     misc_feature    316188..317342
                     /gene="nhaD"
                     /locus_tag="COSY_0318"
                     /note="NHAD transporter family protein; Provisional;
                     Region: PLN00137; cl17324"
                     /db_xref="CDD:247878"
     gene            317368..318087
                     /locus_tag="COSY_0319"
                     /db_xref="GeneID:5171964"
     CDS             317368..318087
                     /locus_tag="COSY_0319"
                     /codon_start=1
                     /transl_table=11
                     /product="Baf family transcriptional regulator"
                     /protein_id="YP_001219168.1"
                     /db_xref="GI:148244474"
                     /db_xref="GeneID:5171964"
                     /translation="MLLYLMYQFESYLLVDIGNTSIKWCLNGKVNSAFITQFNITQLP
                     KVDKIFASCVGDCYILEDLNNTHFVKTERVFNSVECGYQTPSTLGSDRWLAMLASIEH
                     YPKQNLLIIDAGSALTFDLVLANGKHQGGLIMPGLSVLRRSFTQFSNNIQQLSLGLTA
                     NNTQEGWLIGTSQMLMSVINTQIEQHLNNYSNLVVVLTGGDAKIIALKLHRQVKLHQN
                     LVLEGLSSYVQAYKRLHSVLV"
     misc_feature    317404..318048
                     /locus_tag="COSY_0319"
                     /note="Type III pantothenate kinase; Region: Pan_kinase;
                     cl17198"
                     /db_xref="CDD:247752"
     gene            318119..319315
                     /gene="trpS"
                     /locus_tag="COSY_0320"
                     /db_xref="GeneID:5172313"
     CDS             318119..319315
                     /gene="trpS"
                     /locus_tag="COSY_0320"
                     /EC_number="6.1.1.2"
                     /note="catalyzes a two-step reaction, first charging a
                     tryptophan molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanyl-tRNA synthetase"
                     /protein_id="YP_001219169.1"
                     /db_xref="GI:148244475"
                     /db_xref="GeneID:5172313"
                     /translation="MQDRRVLSGMRPTGQLHLGHYHGVLKNWLVLQNEYDSYFFVADW
                     HAFTTHYSDNMNLNVNVIEMVVDWLATGINPNTSTIFVQSKVPEHSELHLLLSMSTPL
                     SWLERVPSYKDQQLKLHIKDLATYGFLGYPLLQSADILIYKAGLVPVGEDQVAHVEFT
                     REVARRFNHLYGREVDFEKKAEISINKMGKKQAKTYRLLRKTYQETGDDEALIKAHAL
                     LQQQNITLGDRERLSGYIEGIGRIILPEPELLLTKASKMPGLDGQKMSKSYCNTISLR
                     DTPKQIQVKIKRMPTDPARIKIINTGNPQKCPVWKLHEVYSNESTCDWVVEGCTKAKF
                     GCIECKQPIINAIEEELTPMQERIAKYQSDPELIKQIIFEGSEKARSIAKETMIEVRE
                     AMGINY"
     misc_feature    318131..319312
                     /gene="trpS"
                     /locus_tag="COSY_0320"
                     /note="tryptophanyl-tRNA synthetase II; Reviewed; Region:
                     PRK12282"
                     /db_xref="CDD:183400"
     misc_feature    318131..>318688
                     /gene="trpS"
                     /locus_tag="COSY_0320"
                     /note="catalytic core domain of tryptophanyl-tRNA
                     synthetase; Region: TrpRS_core; cd00806"
                     /db_xref="CDD:173903"
     misc_feature    order(318137..318151,318167..318169,318173..318178,
                     318185..318187,318236..318238,318251..318253,
                     318365..318367,318509..318511,318521..318523,
                     318530..318532,318557..318559,318563..318568,
                     318572..318577,318584..318586,318686..318688)
                     /gene="trpS"
                     /locus_tag="COSY_0320"
                     /note="active site"
                     /db_xref="CDD:173903"
     misc_feature    318167..318178
                     /gene="trpS"
                     /locus_tag="COSY_0320"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173903"
     misc_feature    order(318248..318250,318257..318262,318383..318388,
                     318392..318400,318407..318412,318416..318427,
                     318431..318436,318497..318499,318503..318508,
                     318515..318520)
                     /gene="trpS"
                     /locus_tag="COSY_0320"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:173903"
     misc_feature    <318845..319312
                     /gene="trpS"
                     /locus_tag="COSY_0320"
                     /note="nucleotidyl transferase superfamily; Region:
                     nt_trans; cl00015"
                     /db_xref="CDD:241550"
     misc_feature    318914..318925
                     /gene="trpS"
                     /locus_tag="COSY_0320"
                     /note="active site"
                     /db_xref="CDD:173912"
     misc_feature    318914..318925
                     /gene="trpS"
                     /locus_tag="COSY_0320"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173912"
     gene            319318..320043
                     /locus_tag="COSY_0321"
                     /db_xref="GeneID:5171930"
     CDS             319318..320043
                     /locus_tag="COSY_0321"
                     /EC_number="4.2.1.70"
                     /note="23S rRNA pseudouridine synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal large subunit pseudouridine synthase
                     B"
                     /protein_id="YP_001219170.1"
                     /db_xref="GI:148244476"
                     /db_xref="GeneID:5171930"
                     /translation="MANRLQKLIANAGYGSRRWVERLIEQGRIEVNNKIAIIGDKTEI
                     TSLVKIDGRKINLSRYVEQETKVIILNKQAGVICSNRDDKGRKSVYSLLPKESRWIMV
                     GRLDLNTSGLLLVTNNGDLANKLMHPSSEIDREYAVRVLGQVKNKDLKKLTQGVVFDD
                     GFSKFNQITFSGGKGANRWYKVVLREGKKREVRRLWEVLGFKVSRLIRIRFGEIRLPD
                     NLKANQYDYLKTVQIKLLFNAVE"
     misc_feature    319318..320040
                     /locus_tag="COSY_0321"
                     /note="16S rRNA uridine-516 pseudouridylate synthase and
                     related pseudouridylate synthases [Translation, ribosomal
                     structure and biogenesis]; Region: RsuA; COG1187"
                     /db_xref="CDD:224108"
     misc_feature    319327..319524
                     /locus_tag="COSY_0321"
                     /note="S4/Hsp/ tRNA synthetase RNA-binding domain; The
                     domain surface is populated by conserved, charged residues
                     that define a likely RNA-binding site;  Found in stress
                     proteins, ribosomal proteins and tRNA synthetases; This
                     may imply a hitherto unrecognized...; Region: S4; cd00165"
                     /db_xref="CDD:238095"
     misc_feature    order(319327..319329,319360..319365,319369..319374,
                     319378..319383,319390..319395,319399..319401,
                     319420..319431,319432..319440,319444..319446)
                     /locus_tag="COSY_0321"
                     /note="RNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238095"
     misc_feature    319513..320004
                     /locus_tag="COSY_0321"
                     /note="Pseudouridine synthase, Escherichia coli RluB like;
                     Region: PseudoU_synth_RluB; cd02556"
                     /db_xref="CDD:211330"
     misc_feature    order(319624..319635,319894..319896)
                     /locus_tag="COSY_0321"
                     /note="probable active site [active]"
                     /db_xref="CDD:211330"
     gene            320193..323060
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /db_xref="GeneID:5172097"
     CDS             320193..323060
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /EC_number="6.1.1.5"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucyl-tRNA synthetase"
                     /protein_id="YP_001219171.1"
                     /db_xref="GI:148244477"
                     /db_xref="GeneID:5172097"
                     /translation="MSDYKSSLNLPSTQFSMKANLANREGKFLKKWQNDRLYDQIRKQ
                     NQGKPKFVLHDGPIYANGDIHIGHAVNKVLKDIIVKSKSLSGFDAPYVPGWDCHGLPI
                     ELNVEKEYGKVGIKIDVNTFRYKCREYADHQVMRQSQDFQRLGILSDWDNPYLTKDFK
                     YEADVVRALGQVVKNGHVYKGHKPLHWCTECGSALAEAEVEYKNKQSEAIDVKFRIIE
                     DSVFNVKKPVSVVIWTTTPWTLPANEAVALHSELNYVLVDIGSEYLLLSQSLVVNSIS
                     RYDIKVTIGERMFSSSELEGLKVQHPFYDKQVPIILGDHVTIDSGTGAVHIAPAHGQE
                     DFIAGLKYNLPIDCPVDAKGVFFKEILLLGGQFIFKANASVIRILKETNTLVKHESLT
                     HSYPHCWRHKTPIIFRITSQWFISMQQNGLRDIVNSEIQKVQWIPHWSKKRIELMVDN
                     RPDWCISRQRFWGVPITLFVHKKTGELHPNTQMLFVCIANRIEQEGIEAWFKSDTKDF
                     IGDDVNDYDKITDILDVWFDSGMSHFVVLKVRKELSNVADLYLEGSDQHRGWFQSSLI
                     SSVAINKKAPYKNVLTHGFVVDKDGKKMSKSLGNIISPQKIVNNVGADILRLWIASTD
                     YTGEMTVSDEILKRSADSYRRIRNTMRFMLANMNGFTQKNLVDTKAMLDLDRWIVAKT
                     QKIQEAIIENYDTYQFHYIVKSINNFCSNDLGGFYLDIIKDRQYTTQKDSPARRSAQT
                     ALYHITQMMVRWLSPILSFTSEEIWQELAPNKKSIFLQEWYLQVDTIDNVVFDDGIIY
                     GTMISSHISQEQREGLEKSDDIFTSINIVRIISPTIRQAIEKLRKDKVLGASLEAEVD
                     IYCNLKVKEKLSKFGEELRFMFITSDVRLHSFEEKPNNAIEVDSDVLQQVAIVVVKSE
                     HSKCVRCWHHRKDVGSNNKYLELCCRCVENVDGDGEVRKFA"
     misc_feature    320193..323033
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="isoleucyl-tRNA synthetase; Reviewed; Region: ileS;
                     PRK05743"
                     /db_xref="CDD:235588"
     misc_feature    320337..>320753
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="nucleotidyl transferase superfamily; Region:
                     nt_trans; cl00015"
                     /db_xref="CDD:241550"
     misc_feature    320385..320396
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="active site"
                     /db_xref="CDD:173912"
     misc_feature    320385..320396
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173912"
     misc_feature    order(320385..320387,320394..320396)
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173912"
     misc_feature    <321078..>321230
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="Leucyl-tRNA synthetase, Domain 2; Region:
                     tRNA-synt_1_2; pfam13603"
                     /db_xref="CDD:222257"
     misc_feature    <321402..322076
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="catalytic core domain of isoleucyl-tRNA
                     synthetases; Region: IleRS_core; cd00818"
                     /db_xref="CDD:173909"
     misc_feature    order(321519..321521,321768..321770,321777..321779,
                     321846..321860,321864..321866,321870..321872,
                     321939..321953,321963..321980)
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="active site"
                     /db_xref="CDD:173909"
     misc_feature    321969..321983
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173909"
     misc_feature    322083..322535
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="Anticodon-binding domain of bacterial and
                     eukaryotic mitochondrial isoleucyl tRNA synthetases;
                     Region: Anticodon_Ia_Ile_BEm; cd07960"
                     /db_xref="CDD:153414"
     misc_feature    order(322092..322094,322104..322106,322113..322115,
                     322125..322127,322134..322136,322143..322148,
                     322287..322289,322296..322301,322308..322313,
                     322320..322322,322335..322337,322347..322349,
                     322356..322358)
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="tRNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:153414"
     misc_feature    order(322134..322136,322143..322145)
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:153414"
     misc_feature    322941..323024
                     /gene="ileS"
                     /locus_tag="COSY_0322"
                     /note="Zinc finger found in FPG and IleRS; Region:
                     zf-FPG_IleRS; pfam06827"
                     /db_xref="CDD:203527"
     gene            323061..324143
                     /gene="aroB"
                     /locus_tag="COSY_0323"
                     /db_xref="GeneID:5172670"
     CDS             323061..324143
                     /gene="aroB"
                     /locus_tag="COSY_0323"
                     /EC_number="4.2.3.4"
                     /note="catalyzes the formation of 3-dehydroquinate from
                     3-deoxy-arabino-heptulonate 7-phosphate; functions in
                     aromatic amino acid biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="YP_001219172.1"
                     /db_xref="GI:148244478"
                     /db_xref="GeneID:5172670"
                     /translation="MKILNLDLGYKSYPIYIGQNLLLKGELLTKHISGKQVMIVTNTT
                     VAPLYLKKVQNLLLSFEFAQVILPDGEKYKTLDTVNCIFSALLEKRFDRSCTLIALGG
                     GVVGDMTGFVAASYQRGVNFIQIPTTLLSQVDSSVGGKTGVNHMLGKNMIGAFHQPKC
                     VLIDIYTLDTLDSQQYSSGMAEVIKYGLLVEYLNFFNFLQENIKDLMDRKQSLIIEMI
                     YQSCQHKINIVAQDELEMGKRTLLNLGHTFGHAIENTLGYGTFLHGEAISVGILMATR
                     LSQLEGYLSSKQVAKIQDLLEKANLPISIIGKINASAFMKAMLVDKKVINGNIRLILL
                     KRLGQAFICDNYNNHLLDQVVNEFCQ"
     misc_feature    323094..324122
                     /gene="aroB"
                     /locus_tag="COSY_0323"
                     /note="Dehydroquinate synthase (DHQS) catalyzes the
                     conversion of DAHP to DHQ in shikimate pathway for
                     aromatic compounds synthesis; Region: DHQS; cd08195"
                     /db_xref="CDD:173954"
     misc_feature    order(323184..323186,323364..323372,323379..323381,
                     323388..323390,323439..323444,323448..323450,
                     323505..323507,323514..323516,323559..323561,
                     323583..323585,323604..323606,323616..323618,
                     323796..323798,323808..323810,323847..323849)
                     /gene="aroB"
                     /locus_tag="COSY_0323"
                     /note="active site"
                     /db_xref="CDD:173954"
     misc_feature    order(323286..323288,323307..323312,323391..323393,
                     323400..323402,323406..323414,323478..323483,
                     323508..323525)
                     /gene="aroB"
                     /locus_tag="COSY_0323"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:173954"
     misc_feature    order(323604..323606,323796..323798,323847..323849)
                     /gene="aroB"
                     /locus_tag="COSY_0323"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:173954"
     gene            324150..324740
                     /locus_tag="COSY_0324"
                     /db_xref="GeneID:5172180"
     CDS             324150..324740
                     /locus_tag="COSY_0324"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219173.1"
                     /db_xref="GI:148244479"
                     /db_xref="GeneID:5172180"
                     /translation="MTDKNKLKVGDDEVMITSSISDLEKMLESVEKHADQRTDTKFER
                     FFLPALAVFGAIIMGFFVVIYSITSDMTRLANSMDPDMGDNMSSMVKSIDSLSYTVGK
                     MTTSVAYMQKDFQQVNKNMNIIASKLDNLDSIAADLTQVSLKMNALEPMLINMEKMNK
                     NMAIMQNSMQWMRRDLNILRSSFSKPLRIFNSIPML"
     gene            324743..325030
                     /gene="gatC"
                     /locus_tag="COSY_0325"
                     /db_xref="GeneID:5172167"
     CDS             324743..325030
                     /gene="gatC"
                     /locus_tag="COSY_0325"
                     /EC_number="6.3.5.-"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA (Gln) amidotransferase subunit C"
                     /protein_id="YP_001219174.1"
                     /db_xref="GI:148244480"
                     /db_xref="GeneID:5172167"
                     /translation="MSLSENQVSQIAHLACLSLNEAQLKDNTQNLNTITSLFEQLANI
                     EIDGVEPMLHPLHMFQRLREDVVSEKEQLALFQSIAPKVRNGYYLVPTVIK"
     misc_feature    324743..325027
                     /gene="gatC"
                     /locus_tag="COSY_0325"
                     /note="aspartyl/glutamyl-tRNA amidotransferase subunit C;
                     Reviewed; Region: gatC; PRK00034"
                     /db_xref="CDD:178810"
     gene            325032..326474
                     /gene="gatA"
                     /locus_tag="COSY_0326"
                     /db_xref="GeneID:5172194"
     CDS             325032..326474
                     /gene="gatA"
                     /locus_tag="COSY_0326"
                     /EC_number="6.3.5.-"
                     /note="allows the formation of correctly charged
                     Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation
                     of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms
                     which lack either or both of asparaginyl-tRNA or
                     glutaminyl-tRNA synthetases; reaction takes place in the
                     presence of glutamine and ATP through an activated
                     phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl/glutamyl-tRNA amidotransferase subunit
                     A"
                     /protein_id="YP_001219175.1"
                     /db_xref="GI:148244481"
                     /db_xref="GeneID:5172194"
                     /translation="MHTKTIVELYKGLKNKDFSCVELTQYYLSRINQSKLNAFITVTD
                     ELALVQAQVADDKIALGNASILTGIPYAHKDIFCTKGVKTSAGSKMLDTFIAPYDATV
                     SQKLNQMNLVMLGKTNMDEFAMGSSNENSFYNAVKNPWNYLKIPGGSSGGSAASVAGG
                     LSCFATGTDTGGSIRQPASLCGITGLKPTYGRISRYGIIAYASSFDQAGIMTKTSQDA
                     AIVLNIMAGFDEKDSTSAEQKVPDYTTNLNNSLQGLIIGLPKEFFLSGLDNEVANNIM
                     FAVKEFESMGAIVKEVSLPNSVYAIPTYYIIASCECSSNLSRLDGVRYGYRSKESKNL
                     EDLYLSSRSEGFGEEVKRRIMIGTYALSTGYYDAYYLKAQKVRRLISNDFKKVFEKVD
                     VIMGPVSPTTAFDLGSVKDPVSMYLADIYTLSVNLAGLPGMSIPVGFAQDLPVGLQLI
                     GNYWSESKLLNIAHQFQLQTDWHLRIPQEC"
     misc_feature    325041..326465
                     /gene="gatA"
                     /locus_tag="COSY_0326"
                     /note="Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit
                     and related amidases [Translation, ribosomal structure and
                     biogenesis]; Region: GatA; COG0154"
                     /db_xref="CDD:223232"
     misc_feature    325068..326432
                     /gene="gatA"
                     /locus_tag="COSY_0326"
                     /note="aspartyl/glutamyl-tRNA amidotransferase subunit A;
                     Reviewed; Region: gatA; PRK00012"
                     /db_xref="CDD:234572"
     gene            326476..327906
                     /gene="gatB"
                     /locus_tag="COSY_0327"
                     /db_xref="GeneID:5172230"
     CDS             326476..327906
                     /gene="gatB"
                     /locus_tag="COSY_0327"
                     /EC_number="6.3.5.-"
                     /note="allows the formation of correctly charged
                     Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation
                     of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms
                     which lack either or both of asparaginyl-tRNA or
                     glutaminyl-tRNA synthetases; reaction takes place in the
                     presence of glutamine and ATP through an activated
                     phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl/glutamyl-tRNA amidotransferase subunit
                     B"
                     /protein_id="YP_001219176.1"
                     /db_xref="GI:148244482"
                     /db_xref="GeneID:5172230"
                     /translation="MKWETVIGLEIHVQLNTKSKIFSSALTKYGKKPNSQACAIDLGL
                     PGVLPVLNVEAVNKAIRFGVAINAHINKRNIFDRKNYFYPDLPKGYQISQMDWPIIGK
                     GKIEIILGNQTKVICITRAHLEEDAGKSIHDMFDDNTAIDLNRAGIPLLEIVSEPDMR
                     SAKEAVAYTKKIHTLVQYIDICDGNMQEGSFRCDANISIRPKGQKELGTRAELKNINS
                     FKFLERAINFEVKRQKDILEEGEKVVQETRLYDSIKNETRSMRLKEETNDYRYFPDPD
                     LLPIEISNELLEKVKQTLPELPDQRKTRFVVELGLSEYDADVLTSQKSLADYFEVMLE
                     DNIVNIKLCANWVMGELSAALNKHQIDIQNSPITAPALSLLISRISDDTISVKTAKDV
                     FKYMWDSKNSADEIIKVRGLKQMTNMVEIEVIIEQVIANSTLQVSQFKLGNNKILGFF
                     IGKIMELTGGKVNPKQVNELLRKKLL"
     misc_feature    326476..327900
                     /gene="gatB"
                     /locus_tag="COSY_0327"
                     /note="aspartyl/glutamyl-tRNA amidotransferase subunit B;
                     Validated; Region: gatB; PRK05477"
                     /db_xref="CDD:235489"
     misc_feature    326485..327345
                     /gene="gatB"
                     /locus_tag="COSY_0327"
                     /note="GatB/GatE catalytic domain; Region: GatB_N;
                     pfam02934"
                     /db_xref="CDD:217294"
     misc_feature    327457..327900
                     /gene="gatB"
                     /locus_tag="COSY_0327"
                     /note="GatB domain; Region: GatB_Yqey; smart00845"
                     /db_xref="CDD:197913"
     gene            complement(328729..329358)
                     /locus_tag="COSY_0328"
                     /db_xref="GeneID:5171985"
     CDS             complement(328729..329358)
                     /locus_tag="COSY_0328"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219177.1"
                     /db_xref="GI:148244483"
                     /db_xref="GeneID:5171985"
                     /translation="MIDIQTLLIWTIPILFAITVHETAHGWIASRLGDHSAKMMGRIT
                     LNPIKHISLIGTILIPAFLYVTSGFIFGWAKPVPINFNALRSPKKDMLWVAIAGPVSN
                     LIMAIIWLMIILLAITINSQFLIEMGQVGIQINLILAVFNLLPLPPLDGARVVSSLLP
                     RKLSYQYNQLEPYGLYILLSLLFLGIFQWTVFPVVKIIQQFMFNITGLI"
     misc_feature    complement(328843..329340)
                     /locus_tag="COSY_0328"
                     /note="Uncharacterized homologs of Site-2 protease (S2P),
                     zinc metalloproteases (MEROPS family M50) which cleave
                     transmembrane domains of substrate proteins, regulating
                     intramembrane proteolysis (RIP) of diverse signal
                     transduction mechanisms. Members of the...; Region:
                     S2P-M50_like_1; cd06158"
                     /db_xref="CDD:100079"
     misc_feature    complement(328879..329325)
                     /locus_tag="COSY_0328"
                     /note="Peptidase family M50; Region: Peptidase_M50;
                     pfam02163"
                     /db_xref="CDD:216910"
     misc_feature    complement(order(328909..328911,328933..328935,
                     329284..329286,329293..329298))
                     /locus_tag="COSY_0328"
                     /note="active site"
                     /db_xref="CDD:100079"
     misc_feature    complement(328924..328935)
                     /locus_tag="COSY_0328"
                     /note="putative substrate binding region [chemical
                     binding]; other site"
                     /db_xref="CDD:100079"
     gene            329393..331075
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /db_xref="GeneID:5172332"
     CDS             329393..331075
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /EC_number="6.1.1.15"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase"
                     /protein_id="YP_001219178.1"
                     /db_xref="GI:148244484"
                     /db_xref="GeneID:5172332"
                     /translation="MKTTKLLIPTQKEAPNDAKIISHQLMIRAGLISKLALGLYSYLP
                     IGIRVLQKVENIIRQEMNKSGAQEVLMPIVQPAELWKESGRWNKYGAELLRFIDRHQR
                     EFCLGPTHEEVITHLARQYLRSYKQLPMNFYQIQTKFRDEIRPRFGVIRMREFIMKDA
                     YSFHIDEASLQETYEVMYKTYCNIFNRLGLNYRIVLADSGSIGGNTSHEFHVLADSGE
                     DTICFSDKSDYAANIEKVTFFKQEKTCQSTMVESKVLTKEKTSIEDVSKFLNVKKVNC
                     VKILIIKIKDGFKALALRGDHELNEIKIHNLFGDFEFSTNNEIKNLGLKKGFIGIKNL
                     DIDLIVDYSASVLCDFVCGANECDYHLIGVNWQGIKFIDADLRNAVDGDYSPDGKGKL
                     MIKRGIEVGHIFQLGTKYSSVMKANVIGESGKAVTTTMGCYGIGVTRIIAAFIEQNHD
                     DKGIIFSQAIAPFQIVIVPINYNKSTRVKALADRLYQQFIKASIDVLLDDRKEHVGIM
                     FADSELLGIPHRIVISDTHADNGSVEYKARNKTNKIEVKFDDALSFIQTKMI"
     misc_feature    329393..331060
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="prolyl-tRNA synthetase; Provisional; Region:
                     PRK09194"
                     /db_xref="CDD:236405"
     misc_feature    329441..>330037
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="Prolyl-tRNA synthetase (ProRS) class II core
                     catalytic domain. ProRS is a homodimer. It is responsible
                     for the attachment of proline to the 3&apos; OH group of
                     ribose of the appropriate tRNA. This domain is primarily
                     responsible for ATP-dependent...; Region: ProRS_core_prok;
                     cd00779"
                     /db_xref="CDD:238402"
     misc_feature    order(329489..329494,329513..329524,329543..329545,
                     329594..329602,329606..329611,329669..329671,
                     329675..329689,329741..329743,329801..329803,
                     329852..329854)
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238402"
     misc_feature    329588..329611
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="motif 1; other site"
                     /db_xref="CDD:238402"
     misc_feature    order(329717..329719,329723..329725,329810..329812,
                     329816..329818,329840..329848,329855..329857,
                     329861..329863,329867..329869)
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="active site"
                     /db_xref="CDD:238402"
     misc_feature    329807..329818
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="motif 2; other site"
                     /db_xref="CDD:238402"
     misc_feature    330071..330490
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="INS is an amino acid-editing domain inserted (INS)
                     into the bacterial class II prolyl-tRNA synthetase (ProRS)
                     however, this CD is not exclusively bacterial. It is also
                     found at the N-terminus of the eukaryotic/archaea-like
                     ProRS&apos;s of yeasts and...; Region: ProRS-INS; cd04334"
                     /db_xref="CDD:239826"
     misc_feature    order(330224..330226,330371..330376,330449..330451)
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="putative deacylase active site [active]"
                     /db_xref="CDD:239826"
     misc_feature    <330566..330733
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="Class II tRNA amino-acyl synthetase-like catalytic
                     core domain. Class II amino acyl-tRNA synthetases (aaRS)
                     share a common fold and generally attach an amino acid to
                     the 3&apos; OH of ribose of the appropriate tRNA.   PheRS
                     is an exception in that it...; Region:
                     class_II_aaRS-like_core; cl00268"
                     /db_xref="CDD:241739"
     misc_feature    order(330581..330586,330596..330598,330686..330691,
                     330695..330700,330707..330709)
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="active site"
                     /db_xref="CDD:238391"
     misc_feature    order(330698..330700,330707..330709)
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="motif 3; other site"
                     /db_xref="CDD:238391"
     misc_feature    330776..331060
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="ProRS Prolyl-anticodon binding domain, short
                     version found predominantly in bacteria. ProRS belongs to
                     class II aminoacyl-tRNA synthetases (aaRS). This alignment
                     contains the anticodon binding domain, which is
                     responsible for specificity in tRNA-binding; Region:
                     ProRS_anticodon_short; cd00861"
                     /db_xref="CDD:238438"
     misc_feature    order(330800..330805,330920..330922,330938..330940,
                     330962..330964,330992..330994,330998..331000)
                     /gene="proS"
                     /locus_tag="COSY_0329"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:238438"
     gene            331082..331894
                     /gene="psd"
                     /locus_tag="COSY_0330"
                     /db_xref="GeneID:5172461"
     CDS             331082..331894
                     /gene="psd"
                     /locus_tag="COSY_0330"
                     /EC_number="4.1.1.65"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="YP_001219179.1"
                     /db_xref="GI:148244485"
                     /db_xref="GeneID:5172461"
                     /translation="MIWWQYVIPQHWLSKLMFRFARIKNVWFKNKFITWFVKSYQINL
                     SEAVRENIKDYQNFNDFFTRELKPDARKIAKSLIICPVDGRVSKVGNINSTQIIQAKN
                     HRYNVEQLLGNDIRSAEFKVGFFATIYLSPKDYHRIHMPYDGKLISMSYILGDLFSVN
                     QVTTENIDGLFARNERVVCYFETEFGLCAFILVGAIFVGSMETVWHGQINPPFQKRIQ
                     HFSYLNQTIELKKGEEMGRFNMGSTVIMLMSNQINKFILKETEMVRMGQALI"
     misc_feature    331094..331888
                     /gene="psd"
                     /locus_tag="COSY_0330"
                     /note="phosphatidylserine decarboxylase; Reviewed; Region:
                     psd; PRK00044"
                     /db_xref="CDD:234591"
     gene            complement(331869..333128)
                     /locus_tag="COSY_0331"
                     /db_xref="GeneID:5172209"
     CDS             complement(331869..333128)
                     /locus_tag="COSY_0331"
                     /note="HlyC/CorC (HCC) family"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt efflux protein"
                     /protein_id="YP_001219180.1"
                     /db_xref="GI:148244486"
                     /db_xref="GeneID:5172209"
                     /translation="MESLSIFWLSIILFGLILSSAFFSSTETSMMAINRYRLKVLSRN
                     NKNAKRTEHLLNNLDSLIGTILLGNNLVNIFASSITTILAIKLWGEGSIVLASLTLTF
                     IILVFAETTPKTFAAKNPEKIALPVSIIIESLIKIFKPFVWIIAQLSKIILTTFSIKS
                     ETNNNLVSSEELKMVVSDAKPVIASNYQKMLLNIIDLEKVKVEDIMIPRHELISIDIN
                     KPDKILKQLQRIQHTRLITYDTSSDNITGVLHMRDIVNLYAKGNFSIDNALALIHKPY
                     FVPEGTSLAHQLAHFQQQKRRLGLIVDEYGEVRGMIVLEDILEEIVGQFTSNQNESID
                     EITKQKDGSYLVDPRINIRELNNLLRLNLSVTNAKTLNGLILETLQSIPKRDVSLKIN
                     NILIEIMQISNQTIKLVKITKLEPVPF"
     misc_feature    complement(331881..333053)
                     /locus_tag="COSY_0331"
                     /note="Putative Mg2+ and Co2+ transporter CorB [Inorganic
                     ion transport and metabolism]; Region: CorB; COG4536"
                     /db_xref="CDD:226911"
     misc_feature    complement(332589..333050)
                     /locus_tag="COSY_0331"
                     /note="Domain of unknown function DUF21; Region: DUF21;
                     pfam01595"
                     /db_xref="CDD:216595"
     misc_feature    complement(332169..332498)
                     /locus_tag="COSY_0331"
                     /note="This cd contains two tandem repeats of the
                     cystathionine beta-synthase (CBS pair) domains associated
                     with the CorC_HlyC domain. CorC_HlyC is a transporter
                     associated domain. This small domain is found in Na+/H+
                     antiporters, in proteins involved in...; Region:
                     CBS_pair_CorC_HlyC_assoc; cd04590"
                     /db_xref="CDD:239963"
     misc_feature    complement(331887..332120)
                     /locus_tag="COSY_0331"
                     /note="Transporter associated domain; Region: CorC_HlyC;
                     smart01091"
                     /db_xref="CDD:215020"
     gene            complement(333165..334451)
                     /gene="eno"
                     /locus_tag="COSY_0332"
                     /db_xref="GeneID:5172041"
     CDS             complement(333165..334451)
                     /gene="eno"
                     /locus_tag="COSY_0332"
                     /EC_number="4.2.1.11"
                     /note="enolase; catalyzes the formation of
                     phosphoenolpyruvate from 2-phospho-D-glycerate in
                     glycolysis"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="YP_001219181.1"
                     /db_xref="GI:148244487"
                     /db_xref="GeneID:5172041"
                     /translation="MEIKQIKAREVIDSRGNPTVEADVILNDDTIGSAMVPSGASTGQ
                     KEALELRDRDKSRYLGKGVLKAVKFVNTEICDTLIGFDINNLSKIDQTMIDLDGTKTK
                     SRLGANTILSVSLAAAHANANRQHKPLYASLNQGGNYKLPVPMMNIINGGEHANNNID
                     IQEFMIIPVGAPSFKEALRYGIEVFHHLKSILEIKGMSTTVGDEGGFAPNLASNEDAI
                     KIILEAINNAGYKPGKDIFIGIDAASSEFYDNDNKTYNLISENKSFSSEEFVNYLAKW
                     VENYPIISIEDGMDENDWNGWNLLTKKLGDKVQLVGDDLYVTNSKILKQGIERNIANS
                     ILIKVNQIGTLTETFATIKVAMNARYTSIMSHRSGETEDTTIADLAVACTCSQIKTGS
                     LSRSDRLAKYNRLLRIEEELGTQAVYPGLNAFNHLN"
     misc_feature    complement(333168..334451)
                     /gene="eno"
                     /locus_tag="COSY_0332"
                     /note="enolase; Provisional; Region: eno; PRK00077"
                     /db_xref="CDD:234617"
     misc_feature    complement(333219..334436)
                     /gene="eno"
                     /locus_tag="COSY_0332"
                     /note="Enolase: Enolases are homodimeric enzymes that
                     catalyse the reversible dehydration of
                     2-phospho-D-glycerate to phosphoenolpyruvate as part of
                     the glycolytic and gluconeogenesis pathways. The reaction
                     is facilitated by the presence of metal ions; Region:
                     enolase; cd03313"
                     /db_xref="CDD:239429"
     misc_feature    complement(order(333222..333224,333231..333236,
                     333243..333245,333252..333257,333261..333269,
                     333336..333344,333822..333824,333828..333830,
                     333849..333854,333891..333896,333903..333908,
                     333915..333920,333981..333989,334353..334355,
                     334389..334391,334401..334427,334431..334433))
                     /gene="eno"
                     /locus_tag="COSY_0332"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239429"
     misc_feature    complement(order(333513..333515,333594..333596,
                     333729..333731,334329..334331))
                     /gene="eno"
                     /locus_tag="COSY_0332"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:239429"
     misc_feature    complement(order(333285..333287,333348..333356,
                     333438..333440,333840..333842,333990..333992))
                     /gene="eno"
                     /locus_tag="COSY_0332"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:239429"
     gene            335016..335279
                     /locus_tag="COSY_0333"
                     /db_xref="GeneID:5172470"
     CDS             335016..335279
                     /locus_tag="COSY_0333"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219182.1"
                     /db_xref="GI:148244488"
                     /db_xref="GeneID:5172470"
                     /translation="MVQSFLNAGEAFNEEKYTKLGINLDNYLHTHFNKNNQLYRVSID
                     SKLGTLAVFEDYAYLSNAYLSVFDQTNDKKWLDRVITLVNVMN"
     misc_feature    <335016..>335273
                     /locus_tag="COSY_0333"
                     /note="Highly conserved protein containing a thioredoxin
                     domain [Posttranslational modification, protein turnover,
                     chaperones]; Region: COG1331"
                     /db_xref="CDD:224250"
     gene            complement(335919..338957)
                     /locus_tag="COSY_0334"
                     /db_xref="GeneID:5172297"
     CDS             complement(335919..338957)
                     /locus_tag="COSY_0334"
                     /note="hydrophobe/amphiphile efflux-1 (HAE1) family in
                     resistance-nodulation-cell division (RND) superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="cation/multidrug efflux pump"
                     /protein_id="YP_001219183.1"
                     /db_xref="GI:148244489"
                     /db_xref="GeneID:5172297"
                     /translation="MDNILIFFVKQKKLALVLTISIIVLGLFTLNSIQRDKFPAVDFE
                     VMTIVTAYPGASPEDVEQNVTNLIEDELRSISGIDKFSSTSKEGKSSIVIILSQDVDD
                     IEPLKQEIRNVVNRIKSLPEEVNGFPWIVDQKNSLKSILKINISSDNLSYQVLRDIID
                     DMSESLSLVKGVSKVIKEGYLDREFQIRVNPDSLYQHKLSLPQVIKAIKNRNKRYTVG
                     NNNDINEKTIVVLAKFDEIEAVSNVIIKSTFDGPVIRLKDIAKITSENKKETSIIRVN
                     GTKGFILSIHKQEHADVITTVDLVKDKVLELEAKYPTSLKFFYSSDESNHVRNRLNIV
                     TNNGLIGLLLVLIILALFLSFKTAFWVSIGLPVSLLGTVSLLGVTGETINLVSLAAMI
                     LILGIVVDDSIVVAESIHHYKQLGKDRYQSTILGFKRVIAPVITTILTTILAFSSMFF
                     MSGTMGKFIYVIPLVVIFSLTLSFLEVSLALPAHLASSDEKTKEKIWFMRIEVWFEGF
                     LTEVLKWRYSVVFIFSIVLIGSLYFAKTQMKYVQFPIVGADSIDARLNMPIGTSLERT
                     ESISKQVEKIIIEVVGEDLDSLTNNIGHYFTNVAKFSIELVPSSIRVETSKSLLAKLK
                     KRVKDIKFAQELKFSISRPGPSQGEDVEINLIGSDNIQRQNAADTLEKILLGIDGIDN
                     IERDDESGKARIEVVIDFEKMSRFDVDFSVVDDYLKAVFTGTNVTSVRYGDNNVYFRI
                     YLGSDKQSKNFLTLLKINNRQGRPIPLKQFVSLKKIKGEPNFNHFNGQRSVMFSGSVD
                     DEVTTSGEVISQALKQLDLVSKYPAIQMTSEGGNKDTKKTMDSFKKAFIMAIFSIFLL
                     LILLFNSYSQPILVLIAVPFSIIGVIWAFFLHGETLSFFAILGTLALVGVIVNDSLIM
                     VTHLNYLKVKLASTMSVYKWVAQGAKDRLRAVVLTTLTTLAGVIPLAYGIGGTDFILQ
                     PMALSLGYGLLFGTLMTLVLLPCLYLINHELINWLKKTFG"
     misc_feature    complement(336033..338939)
                     /locus_tag="COSY_0334"
                     /note="Cation/multidrug efflux pump [Defense mechanisms];
                     Region: AcrB; COG0841"
                     /db_xref="CDD:223911"
     misc_feature    complement(337536..>337814)
                     /locus_tag="COSY_0334"
                     /note="Protein export membrane protein; Region: SecD_SecF;
                     cl14618"
                     /db_xref="CDD:246677"
     gene            complement(339045..340847)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /db_xref="GeneID:5172472"
     CDS             complement(339045..340847)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding elongation factor family protein"
                     /protein_id="YP_001219184.1"
                     /db_xref="GI:148244490"
                     /db_xref="GeneID:5172472"
                     /translation="MNTKLRNIAIIAHVDHGKTTLVDKLLEQSQTFDARFESSDRMMD
                     SNDLEKERGITISSKNTAIKWYDYHINIVDTPGHADFGGEVERILSMVDSVLLLVDAQ
                     EGPMPQTRFVTRKAFEQGLNPIVVINKIDKDAARPDWVIGQVFDLFDQLGATDKQLDF
                     PIIYASGINGYASLDDDTRSGDMTPMFETIVKQVKAPEVDIDAPLQMQITALDYSSFV
                     GSISIGRITRGTIKKNMQVVVVGVDGGKRKAKITSLQGFLGLNKIDTNSAQAGNIVCI
                     TGIKNISISDTICDPGTIESLPPLSVDEPTVSMAFRVNDSPFAGQDGKFITSRNIRDR
                     LDKELIYNISLRVENTSDPSEFVVLGRGVLHLSILIETMRREGFELAVGRPQVILRKI
                     DGVICEPFEDLSLDVEIQHQGTMMKKLGERKAKLTNMIPDGNGRVRLDFNIPARGLIG
                     FRTEFLIATTGTGLMNATFDTYKLQQPGEIGQRSNGSLISMNQGQAVAYAIFNLQKSG
                     KFFIEHNTDIYEGMVVGIHTRYQDLMINVMKGKQLTNVRASGTDEAVSLTPAIKLDLE
                     KALEFIDNDELVEVTPHNIRIRKRLLTVSERKGA"
     misc_feature    complement(339048..340847)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="Predicted membrane GTPase involved in stress
                     response [Signal transduction mechanisms]; Region: TypA;
                     COG1217"
                     /db_xref="CDD:224138"
     misc_feature    complement(340257..340838)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="Tyrosine phosphorylated protein A (TypA)/BipA
                     family belongs to ribosome-binding GTPases; Region:
                     TypA_BipA; cd01891"
                     /db_xref="CDD:206678"
     misc_feature    complement(340791..340814)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="G1 box; other site"
                     /db_xref="CDD:206678"
     misc_feature    complement(order(340419..340421,340431..340433,
                     340539..340544,340611..340616,340668..340673,
                     340767..340772,340779..340781,340788..340793,
                     340803..340805,340809..340811))
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="putative GEF interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:206678"
     misc_feature    complement(order(340344..340352,340455..340457,
                     340461..340466,340788..340805))
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206678"
     misc_feature    complement(340671..340706)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206678"
     misc_feature    complement(340683..340685)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="G2 box; other site"
                     /db_xref="CDD:206678"
     misc_feature    complement(340617..340628)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="G3 box; other site"
                     /db_xref="CDD:206678"
     misc_feature    complement(340566..340622)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206678"
     misc_feature    complement(340455..340466)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="G4 box; other site"
                     /db_xref="CDD:206678"
     misc_feature    complement(340344..340352)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="G5 box; other site"
                     /db_xref="CDD:206678"
     misc_feature    complement(339978..340235)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="BipA_TypA_II: domain II of BipA (also called TypA)
                     having homology to domain II of the elongation factors
                     (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein
                     with global regulatory properties in Escherichia coli.
                     BipA is phosphorylated on a...; Region: BipA_TypA_II;
                     cd03691"
                     /db_xref="CDD:239662"
     misc_feature    complement(339432..339656)
                     /gene="bipA"
                     /locus_tag="COSY_0335"
                     /note="BipA_TypA_C: a C-terminal portion of BipA or TypA
                     having homology to the C terminal domains of the
                     elongation factors EF-G and EF-2. A member of the ribosome
                     binding GTPase superfamily, BipA is widely distributed in
                     bacteria and plants.  BipA is a highly...; Region:
                     BipA_TypA_C; cd03710"
                     /db_xref="CDD:239681"
     gene            340918..341550
                     /gene="ftsJ"
                     /locus_tag="COSY_0336"
                     /db_xref="GeneID:5172489"
     CDS             340918..341550
                     /gene="ftsJ"
                     /locus_tag="COSY_0336"
                     /EC_number="2.1.1.-"
                     /note="ribosomal RNA large subunit methyltransferase J"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein methyltransferase FtsJ"
                     /protein_id="YP_001219185.1"
                     /db_xref="GI:148244491"
                     /db_xref="GeneID:5172489"
                     /translation="MSKKDSSRRWMREHINDKFVKNAKKAGYRSRAVYKLIEVINKEK
                     FIKPGNKVIDLGAAPGSWSQMAIKAVGKSGQVIANDILNIKPIDGIDFLQGDFTENSV
                     YEALLNLTMNQKVNVVLSDIAPNISGQPSVDIPKSMYLCELALDIAIKSLTPSGYFFV
                     KVFQGDGFDMFVESCRTYFSYVTIHKPKASRTRSKEVYLLANKLKPAKLM"
     misc_feature    340933..341541
                     /gene="ftsJ"
                     /locus_tag="COSY_0336"
                     /note="23S rRNA methylase [Translation, ribosomal
                     structure and biogenesis]; Region: FtsJ; COG0293"
                     /db_xref="CDD:223370"
     misc_feature    341068..341406
                     /gene="ftsJ"
                     /locus_tag="COSY_0336"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(341080..341100,341155..341160,341200..341208,
                     341278..341280)
                     /gene="ftsJ"
                     /locus_tag="COSY_0336"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            341601..342572
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /db_xref="GeneID:5172029"
     CDS             341601..342572
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /EC_number="2.5.1.30"
                     /note="trans-hexaprenyltranstransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl-diphosphate synthase"
                     /protein_id="YP_001219186.1"
                     /db_xref="GI:148244492"
                     /db_xref="GeneID:5172029"
                     /translation="MKNLSDIQSLIKLDLKKTDEILINRLSSNVALINQMSHYIIHAG
                     GKRLRPLLLLLCARATGYQGTHHYLMAVVIELIHTATLLHDDIVDESSTRRGKDTVNE
                     VWGNAPSILVGDFLYSRAFEIMVEPNLMSIMCILSKTTNNIAEGEVLQLLNCQNDELT
                     EVEYYAVIKQKTACLFQAATQIGGLLSAVNKTQETALKNYGLHLGNAFQIIDDVLDYE
                     SDAKTIGKEVGDDLSEGKTTLPMIYALSHTSGNDKQLLKDAINQADNSKIVQVIKILQ
                     SVKAFDYTRNQAYKSAQLAKQSLNLIPNSEYKDALILLCDLSLQRQS"
     misc_feature    341613..342569
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /note="Geranylgeranyl pyrophosphate synthase [Coenzyme
                     metabolism]; Region: IspA; COG0142"
                     /db_xref="CDD:223220"
     misc_feature    341682..342563
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /note="Trans-Isoprenyl Diphosphate Synthases,
                     head-to-tail; Region: Trans_IPPS_HT; cd00685"
                     /db_xref="CDD:173833"
     misc_feature    order(341829..341831,341838..341846,341850..341858,
                     341862..341867,341880..341885,342039..342041,
                     342048..342050,342111..342116,342123..342125,
                     342234..342239,342246..342248,342276..342278,
                     342291..342293,342306..342308)
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173833"
     misc_feature    341838..341867
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /note="chain length determination region; other site"
                     /db_xref="CDD:173833"
     misc_feature    order(341853..341858,341865..341867,341880..341885,
                     342048..342050,342111..342113,342234..342239,
                     342246..342248,342276..342278,342291..342293,
                     342306..342308)
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /note="substrate-Mg2+ binding site; other site"
                     /db_xref="CDD:173833"
     misc_feature    order(341853..341858,341865..341867,341880..341885,
                     342111..342113,342234..342239)
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:173833"
     misc_feature    order(341853..341858,341865..341867,341880..341885,
                     342048..342050,342111..342113)
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /note="aspartate-rich region 1; other site"
                     /db_xref="CDD:173833"
     misc_feature    order(341871..341915,342255..342260,342276..342293,
                     342300..342314)
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /note="active site lid residues [active]"
                     /db_xref="CDD:173833"
     misc_feature    order(342234..342239,342246..342248,342276..342278,
                     342291..342293,342306..342308)
                     /gene="ispB"
                     /locus_tag="COSY_0337"
                     /note="aspartate-rich region 2; other site"
                     /db_xref="CDD:173833"
     gene            342577..344637
                     /gene="dinG"
                     /locus_tag="COSY_0338"
                     /db_xref="GeneID:5171974"
     CDS             342577..344637
                     /gene="dinG"
                     /locus_tag="COSY_0338"
                     /EC_number="3.6.1.-"
                     /note="helicase involved in DNA repair and perhaps also
                     replication"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="YP_001219187.1"
                     /db_xref="GI:148244493"
                     /db_xref="GeneID:5171974"
                     /translation="MLSNELKTKIHQSFKNLKENMNGFITRQAQNKMIAEISKTLSGE
                     YKNSHNILCVEAPTGIGKTFAYLLGSIHIAKANKKKLIISSANVALQEQLFFKDIPQA
                     QQYCCVDFEYTLIKGRSRYVCIRNLINICEDNKNDNPLFESMPLFDKPPEEYPLEQLS
                     KMLYNYSTKKWNGEIDDLIPTTNHSIWQQIACNRFTCTVKNCEFYKDCAFFKTRQKIT
                     KADVIVANHDLVLADLSTGNTVLPDVSKSIFIFDEAHHLNSKALSHFSLTTSTEFIKT
                     SVKQTKEVSETLCKISKQNIPNINIKQIDNYITDLIQLLEQLKFNENIYLFNQGVIDE
                     PIKQISRNILTLIEIIQTKFTLLKEFWSDYLKKTVINKSIHGPINNMAGQCEQHLLSI
                     IALFSSFLQIDEPNKIPNSRWIKKSILTTSKRTNYLLNSAQTDISENLDHLIWSKASG
                     AILTSATLTSLGSFERLNKQLGLLRNENQYLRLPSPFMFNQVDLIIAKLKASPTQVYE
                     HTQETTLQLLKRLDSDEGSLVLFTSNKQMQIVANLIDKKLNCTLFIQGEYPKKNILKK
                     HINLRKQGKGSIIFGLDSFSEGIDLKGNNLTHVIITKLRFSVPTSPIDRTLATYLKSQ
                     NRNPFMEISLPDASLKLIQACGRLIRTETDVGKITIFDNRLISKFYGKLLLNALPNYN
                     IIIE"
     misc_feature    342577..344634
                     /gene="dinG"
                     /locus_tag="COSY_0338"
                     /note="ATP-dependent DNA helicase DinG; Provisional;
                     Region: dinG; PRK11747"
                     /db_xref="CDD:236966"
     misc_feature    <343171..343374
                     /gene="dinG"
                     /locus_tag="COSY_0338"
                     /note="DEAD_2; Region: DEAD_2; pfam06733"
                     /db_xref="CDD:219153"
     misc_feature    344152..344619
                     /gene="dinG"
                     /locus_tag="COSY_0338"
                     /note="Helicase C-terminal domain; Region: Helicase_C_2;
                     pfam13307"
                     /db_xref="CDD:222037"
     gene            complement(344647..346095)
                     /gene="trkH"
                     /locus_tag="COSY_0339"
                     /db_xref="GeneID:5172241"
     CDS             complement(344647..346095)
                     /gene="trkH"
                     /locus_tag="COSY_0339"
                     /note="K+ transporter (Trk) family"
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system, membrane component"
                     /protein_id="YP_001219188.1"
                     /db_xref="GI:148244494"
                     /db_xref="GeneID:5172241"
                     /translation="MQFSIVFKTVGLLLMLFSLTQLPPIIVDFIYAQNEALYFITAFF
                     LTLLSGFVLWLPFKNSTKDFRIREGVLVVVSFWLVLSLFATTPFLLSTSLEMSFSDAF
                     FESMSGLTTTGATVLSGLDGLPKALLYYRQQLQWLGGMGIIVLAVAILPMLGVGGMEL
                     YHAESSGISKERLTPKLTQTAKALWKIYISLTVACALSYYFAGMDVFNAIGYSYSTIA
                     IGGFSTHDVSIGYFNSYAIELVAIIFMLLAGVNFSLHFLVWRKNNIFIYLKDSEFKTY
                     LLILGISIMLISGYLFDTGYYKTIEESVRYGVFQSVSMVTTTGFVSTDFSLWPFVLPV
                     FLIFVSFIGACAGSTGGGIKVVRILLMFKLAMQEIKKFIHPNAQINIKLNQKSVSENT
                     LVSVWGFLSLYVIAFVVIMLMLMFSGLEQVSAFSAAAASINNLGPGLGDVSANYGGIS
                     DTAKWILSFSMLLGRLEILTLMALLHKAFWRF"
     misc_feature    complement(344653..346095)
                     /gene="trkH"
                     /locus_tag="COSY_0339"
                     /note="Cation transport protein; Region: TrkH; cl17365"
                     /db_xref="CDD:247919"
     misc_feature    complement(344701..345846)
                     /gene="trkH"
                     /locus_tag="COSY_0339"
                     /note="potassium uptake protein, TrkH family; Region:
                     2a38; TIGR00933"
                     /db_xref="CDD:233196"
     gene            complement(346108..347481)
                     /gene="trkA"
                     /locus_tag="COSY_0340"
                     /gene_synonym="sapG"
                     /db_xref="GeneID:5172212"
     CDS             complement(346108..347481)
                     /gene="trkA"
                     /locus_tag="COSY_0340"
                     /gene_synonym="sapG"
                     /note="involved in potassium uptake; found to be
                     peripherally associated with the inner membrane in
                     Escherichia coli; contains an NAD-binding domain"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="YP_001219189.1"
                     /db_xref="GI:148244495"
                     /db_xref="GeneID:5172212"
                     /translation="MKILILGAGQVGTTLAKYLGLDNDNDISIIDKDESNLLNLQRHL
                     DIKTVCGHASYPNILEEADIKNMDMVIAVTRSDEGNMLACQMAHTLYQVEKKVARVRT
                     AEYLHRKELFSPNAIPIDFVITPEELVTNYIKRMVEEPGAEQVFEFENGLVQLVETRA
                     YKGTPIVGHPIKDLHEHLPKTWVRIVSLYRNSRAIPASGETVIRDGDRVYFMTKKASI
                     SKVIKQFRREDRTYKNIIIAGGGRIGLNLAKFLEKDHRIRVIEMNKQRVNEIADELEN
                     TLVLLGNASDEELLLEEGIENTDLFLALTDSDEINVIVSILAKRLGAYKTVALVKRNV
                     YEDLAEQSEDVDMVISPDQITVGGILAHIRKGDTMTAYSLRQGKAEAIEIIVHGDKYH
                     SDVVGKTIEQINLPNGVVVGSVVRNNEVIMGSRRLIIKEGDHVLLVLTDVSKIHEVEK
                     LFEGYFD"
     misc_feature    complement(346123..347481)
                     /gene="trkA"
                     /locus_tag="COSY_0340"
                     /gene_synonym="sapG"
                     /note="potassium transporter peripheral membrane
                     component; Reviewed; Region: trkA; PRK09496"
                     /db_xref="CDD:236541"
     misc_feature    complement(347107..347475)
                     /gene="trkA"
                     /locus_tag="COSY_0340"
                     /gene_synonym="sapG"
                     /note="TrkA-N domain; Region: TrkA_N; pfam02254"
                     /db_xref="CDD:216949"
     misc_feature    complement(346804..347019)
                     /gene="trkA"
                     /locus_tag="COSY_0340"
                     /gene_synonym="sapG"
                     /note="TrkA-C domain; Region: TrkA_C; pfam02080"
                     /db_xref="CDD:216867"
     misc_feature    complement(346429..346779)
                     /gene="trkA"
                     /locus_tag="COSY_0340"
                     /gene_synonym="sapG"
                     /note="TrkA-N domain; Region: TrkA_N; pfam02254"
                     /db_xref="CDD:216949"
     gene            complement(347488..348063)
                     /locus_tag="COSY_0341"
                     /db_xref="GeneID:5172223"
     CDS             complement(347488..348063)
                     /locus_tag="COSY_0341"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator"
                     /protein_id="YP_001219190.1"
                     /db_xref="GI:148244496"
                     /db_xref="GeneID:5172223"
                     /translation="MDDVLVIGSILIIDDENINAETMMDILEDVNYHVVLAANANQAK
                     IIIKDQSFDLVMMDVWMPGQDGMSLLEEWTQADFSTPIVMMSGHAEHQDVVKAIKFGA
                     VDFLKKPLHDFLPLIRKILSEQVLEKSRYNVNNIEFNVPLKEARNIFEVQYFNHHLKE
                     NNHNIAKVAAFAGLERTTLYRKLKDLGIDKK"
     misc_feature    complement(347674..348039)
                     /locus_tag="COSY_0341"
                     /note="FOG: CheY-like receiver [Signal transduction
                     mechanisms]; Region: CheY; COG0784"
                     /db_xref="CDD:223855"
     misc_feature    complement(347701..348033)
                     /locus_tag="COSY_0341"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(347737..347742,347749..347751,
                     347806..347808,347866..347868,347890..347892,
                     348019..348024))
                     /locus_tag="COSY_0341"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(347890..347892)
                     /locus_tag="COSY_0341"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(347866..347874,347878..347883))
                     /locus_tag="COSY_0341"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(347734..347742)
                     /locus_tag="COSY_0341"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(347506..>347592)
                     /locus_tag="COSY_0341"
                     /note="Bacterial regulatory protein, Fis family; Region:
                     HTH_8; cl17420"
                     /db_xref="CDD:247974"
     gene            complement(348076..350238)
                     /locus_tag="COSY_0342"
                     /db_xref="GeneID:5172434"
     CDS             complement(348076..350238)
                     /locus_tag="COSY_0342"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="YP_001219191.1"
                     /db_xref="GI:148244497"
                     /db_xref="GeneID:5172434"
                     /translation="MVLNQYLSLKKTPPAWIWVLIFLLSISGTFYLGLNPDFIAHWWG
                     YLVGFNIIMSLVAVYYVYVDVLRLKRDVKGDVVGSKFTWSFVKIVPVLVIVPVLSFYM
                     FSFQTIQNNVKDSEKAFNVFSQNFIQQVNGLYSGVQKIRDERYTEQTKRLLTLITSFG
                     SFQKDVKNYAQSMQIFLDGLIDKGWACQITLLNAQEEMVAKTANVTNCMVIKEQPLLG
                     AQPRMINEDETANVIQVKMSTRYLFNVSSQDIFVIDVVYATDPGLLGFLSQVRGFASA
                     AQNIKFEINTSITQKRFMIDFSSTILLAILSAIMVVFRMIERLMKPLNNLSIAAQEIA
                     KGNYDVRIAKQEESEDVRSLIEQFNTMSRQIKASREDLDTHNLYLETILKYSYGVIAL
                     DQNRKIRLINPVVGTMLGIKDEKLFIGKKCNIIVDCCSNLEPLFLMTQDKFKQDESEW
                     SEEIEITLVDRHLLLSCQGAALKNDNETLGFVIIIKDISKLNRAQKKAAWGEVAKRMA
                     HEIKNPLTPILLSAQRLRNRFLISLEGKDLDVIDKTTNTIIHQVQSMDAMLSAFADYA
                     NTPQVERMPCNLNALINQSILLYDDISKMNIDLDLAVNIPLLFLDSNSISRVLINLVK
                     NASEAMIDGRDLNVKIVTEYLLKQAIVRLSIIDNGDGFDKHVIDRVFEPYVTTKAQGG
                     GLGMTIVQNIIKQHKAKIFASNINPHGAMITIEFDCKG"
     misc_feature    complement(348079..349356)
                     /locus_tag="COSY_0342"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: VicK; COG5002"
                     /db_xref="CDD:227335"
     misc_feature    complement(349138..349284)
                     /locus_tag="COSY_0342"
                     /note="Histidine kinase, Adenylyl cyclase,
                     Methyl-accepting protein, and Phosphatase (HAMP) domain.
                     HAMP is a signaling domain which occurs in a wide variety
                     of signaling proteins, many of which are bacterial. The
                     HAMP domain consists of two alpha helices...; Region:
                     HAMP; cd06225"
                     /db_xref="CDD:100122"
     misc_feature    complement(order(349144..349149,349156..349161,
                     349165..349170,349177..349182,349186..349188,
                     349192..349194,349240..349242,349246..349251,
                     349258..349263,349267..349272,349279..349284))
                     /locus_tag="COSY_0342"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100122"
     misc_feature    complement(348541..348747)
                     /locus_tag="COSY_0342"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    complement(order(348553..348555,348565..348567,
                     348574..348576,348586..348588,348595..348597,
                     348625..348627,348676..348678,348685..348687,
                     348697..348699,348706..348708,348718..348720,
                     348730..348732))
                     /locus_tag="COSY_0342"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    complement(348712..348714)
                     /locus_tag="COSY_0342"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    complement(348091..348396)
                     /locus_tag="COSY_0342"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(348103..348105,348109..348114,
                     348127..348129,348133..348135,348181..348192,
                     348253..348258,348262..348264,348268..348270,
                     348274..348276,348355..348357,348364..348366,
                     348376..348378))
                     /locus_tag="COSY_0342"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(348364..348366)
                     /locus_tag="COSY_0342"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(348184..348186,348190..348192,
                     348256..348258,348262..348264))
                     /locus_tag="COSY_0342"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            350851..351381
                     /gene="ppa"
                     /locus_tag="COSY_0343"
                     /db_xref="GeneID:5172372"
     CDS             350851..351381
                     /gene="ppa"
                     /locus_tag="COSY_0343"
                     /EC_number="3.6.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic pyrophosphatase"
                     /protein_id="YP_001219192.1"
                     /db_xref="GI:148244498"
                     /db_xref="GeneID:5172372"
                     /translation="MQNSLKPVSAGNIPDEVNVIIEIPANSSPIKYEIDKETGAMFVD
                     RFISTPMFYPCNYGFVPETLSDDGDPTDILVITPYPLIHDSVITARPIGILYMTDEAG
                     KDSKILAVPIDKLCKSYHDIKCIDDVGITLKKQIEHFFTYYKDLEEGKWVKIDGWGNS
                     IKAKKELQASFNYYYQ"
     misc_feature    350893..351363
                     /gene="ppa"
                     /locus_tag="COSY_0343"
                     /note="Inorganic pyrophosphatase. These enzymes hydrolyze
                     inorganic pyrophosphate (PPi) to two molecules of
                     orthophosphates (Pi). The reaction requires bivalent
                     cations. The enzymes in general exist as homooligomers;
                     Region: pyrophosphatase; cd00412"
                     /db_xref="CDD:238239"
     misc_feature    order(350923..350928,351085..351090)
                     /gene="ppa"
                     /locus_tag="COSY_0343"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238239"
     misc_feature    order(350941..350943,350983..350985,351019..351021,
                     351277..351282)
                     /gene="ppa"
                     /locus_tag="COSY_0343"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238239"
     misc_feature    order(350947..350949,351049..351051,351064..351066,
                     351145..351147,351160..351162)
                     /gene="ppa"
                     /locus_tag="COSY_0343"
                     /note="metal binding sites [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:238239"
     gene            351311..351952
                     /locus_tag="COSY_0344"
                     /db_xref="GeneID:5171821"
     CDS             351311..351952
                     /locus_tag="COSY_0344"
                     /note="Similar to N6-adenine-specific DNA methylase."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="YP_001219193.1"
                     /db_xref="GI:148244499"
                     /db_xref="GeneID:5171821"
                     /translation="MMVGVILLKPKKSFKLLLTITINNFFQIGSGKYRGKKFNFPYTP
                     TLRPTSGRIRETLFNWIQFESYNKTYLDLFAGSGALSFEALSRGAKQVTSFEKDYNTY
                     QNLQKNKALLKTNKINIFNQDALNFLSHKSTQTFDFIFLDPPFNKNYLPKTLKALIDG
                     NYITLNTKIYIESEFKISENIVTKWLSTNIQINKQKHAGKIHYCLITLLQNFD"
     misc_feature    351383..351925
                     /locus_tag="COSY_0344"
                     /note="N6-adenine-specific methylase [DNA replication,
                     recombination, and repair]; Region: COG0742"
                     /db_xref="CDD:223813"
     misc_feature    351521..351823
                     /locus_tag="COSY_0344"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(351527..351547,351596..351601,351674..351682,
                     351734..351736)
                     /locus_tag="COSY_0344"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            351965..352441
                     /gene="coaD"
                     /locus_tag="COSY_0345"
                     /db_xref="GeneID:5172292"
     CDS             351965..352441
                     /gene="coaD"
                     /locus_tag="COSY_0345"
                     /EC_number="2.7.7.3"
                     /note="Catalyzes the conversion of ATP and pantetheine
                     4'-phosphate to diphosphate and 3'-dephospho-coA"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantetheine adenylyltransferase"
                     /protein_id="YP_001219194.1"
                     /db_xref="GI:148244500"
                     /db_xref="GeneID:5172292"
                     /translation="MKKIAIYPGSFDPITNGHVDLIKRASKLFDEIIIGISQNSKKKA
                     FLSINDRIDTINTALKDINNIRILSFDTLLVDFASLKNAQVILRGLRAISDFEYEYQL
                     SGINKHLNPNIETLFMTPTEQYANISSSLIKEIIALGGDISVFVPASVKTLLKHRL"
     misc_feature    351968..352438
                     /gene="coaD"
                     /locus_tag="COSY_0345"
                     /note="phosphopantetheine adenylyltransferase;
                     Provisional; Region: coaD; PRK00168"
                     /db_xref="CDD:234674"
     misc_feature    351974..352429
                     /gene="coaD"
                     /locus_tag="COSY_0345"
                     /note="Phosphopantetheine adenylyltransferase; Region:
                     PPAT; cd02163"
                     /db_xref="CDD:173914"
     misc_feature    order(351983..351997,352013..352018,352025..352027,
                     352073..352075,352088..352090,352178..352186,
                     352226..352231,352235..352237,352256..352261,
                     352268..352270,352280..352282,352322..352324,
                     352334..352336,352343..352345)
                     /gene="coaD"
                     /locus_tag="COSY_0345"
                     /note="active site"
                     /db_xref="CDD:173914"
     misc_feature    352007..352018
                     /gene="coaD"
                     /locus_tag="COSY_0345"
                     /note="(T/H)XGH motif; other site"
                     /db_xref="CDD:173914"
     gene            352518..354422
                     /gene="dnaK"
                     /locus_tag="COSY_0346"
                     /db_xref="GeneID:5172125"
     CDS             352518..354422
                     /gene="dnaK"
                     /locus_tag="COSY_0346"
                     /note="heat shock protein 70; assists in folding of
                     nascent polypeptide chains; refolding of misfolded
                     proteins; utilizes ATPase activity to help fold;
                     co-chaperones are DnaJ and GrpE; multiple copies in some
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="YP_001219195.1"
                     /db_xref="GI:148244501"
                     /db_xref="GeneID:5172125"
                     /translation="MSKIIGIDLGTTNSCVAIMDGGSVKIIENSEGDRTTPSIIAYPK
                     DSEEVLVGQAAKRQAVTNPENTLYAIKRLIGRRFEEDAVQKDIDLVPYKIVKADNGDA
                     WVKVKNKKMAAPEISAKVIGKMKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGK
                     IAGLNVKRIINEPTAAALAYGVDKVKGDKTVVVYDLGGGTFDVSIIEMEDIDGEKHFE
                     VLSTNGDTFLGGEDFDQRMIGYLVDEFKKDQGVDLTNDPMALQRLKEAAEKAKIELSS
                     SEQTEVNLPYVTADASGPKHLNIKITRAKLESLVEDLLKRTIEPCKTALKDADLSTGD
                     IDEVILVGGQTRMPKVTKMVQNFFDKEPKKDVNPDEAVAMGAAIQAGVLGGDVKDVLL
                     LDVTPLSLGIETMGGVMTKLIEKNTTIPTNASQIFSTAADNQSAVTVHVLQGEREISS
                     ANKSLGQFNLEGINSAPKGQPQIEVTLDIDSDGILNVSAKDKNTGKKQSITIKASSGL
                     SDEEVEKMVKDAEAHADEDQKFQKLVTSKNMADALIHSTKQTLDELKDEISIDEKSVI
                     EASITDLEKVIKSDNKEAIDTKVKTLSEKAQLLAEKAQAKAGVKNTPQEEKNSDDVVD
                     ADFEEVKDDK"
     misc_feature    352518..354419
                     /gene="dnaK"
                     /locus_tag="COSY_0346"
                     /note="molecular chaperone DnaK; Provisional; Region:
                     dnaK; PRK00290"
                     /db_xref="CDD:234715"
     misc_feature    352518..353657
                     /gene="dnaK"
                     /locus_tag="COSY_0346"
                     /note="Nucleotide-Binding Domain of the sugar
                     kinase/HSP70/actin superfamily; Region:
                     NBD_sugar-kinase_HSP70_actin; cl17037"
                     /db_xref="CDD:247684"
     misc_feature    order(352539..352550,352554..352556,352560..352562,
                     353031..353033,353097..353099,353103..353111,
                     353541..353543)
                     /gene="dnaK"
                     /locus_tag="COSY_0346"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212657"
     gene            354494..355591
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /db_xref="GeneID:5172273"
     CDS             354494..355591
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /note="chaperone Hsp40; co-chaperone with DnaK;
                     Participates actively in the response to hyperosmotic and
                     heat shock by preventing the aggregation of
                     stress-denatured proteins and by disaggregating proteins,
                     also in an autonomous, dnaK-independent fashion"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone protein DnaJ"
                     /protein_id="YP_001219196.1"
                     /db_xref="GI:148244502"
                     /db_xref="GeneID:5172273"
                     /translation="MSQRDFYEILGIAKNTDVKQIKKAYKRLAMKHHPDRVKDNKELA
                     EKKFKEIQKAYAILSDTQKRQAYDQFGHAGINGNAGATSGTSFSSSGFGDIFGDIFGG
                     GSQQSNNRGSDLRYDLEIDLKEAAQGTTVKIRIPKNETCDTCSGTGAKPGTSVKTCLT
                     CGGAGQIQIQQGFFAVQRPCNACSGTGQRIESTCNNCHGKGVVHKQKTLSVKIPAGVD
                     TGNRIRLSGEGEAGIRGGLSGDLYVQIHVKKHAIFERQDSDLYCEVPIDFATAVLGGQ
                     VEVPTLDNKLNIKVPAGTQTGKLFRLRSKGITHLQHGGSGDVICKVKLETPINLSKKQ
                     QDLLQKFSNSCGKKHHPESNSFFGKMKSFFE"
     misc_feature    354494..355588
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /note="chaperone protein DnaJ; Provisional; Region:
                     PRK10767"
                     /db_xref="CDD:236757"
     misc_feature    354506..354673
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /note="DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock
                     protein 40) proteins are highly conserved and play crucial
                     roles in protein translation, folding, unfolding,
                     translocation, and degradation. They act primarily by
                     stimulating the ATPase activity of Hsp70s; Region: DnaJ;
                     cd06257"
                     /db_xref="CDD:99751"
     misc_feature    order(354590..354598,354626..354628,354635..354640,
                     354647..354652)
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /note="HSP70 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99751"
     misc_feature    354830..>354913
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /note="C-terminal substrate binding domain of DnaJ and
                     HSP40; Region: DnaJ_C; cl03262"
                     /db_xref="CDD:243362"
     misc_feature    order(354839..354841,354884..354901)
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /note="substrate binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:199909"
     misc_feature    354914..355096
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /note="Zinc finger domain of DnaJ and HSP40; Region:
                     DnaJ_zf; cd10719"
                     /db_xref="CDD:199908"
     misc_feature    order(354914..354916,354923..354925,354965..354967,
                     354974..354976,355031..355033,355040..355042,
                     355073..355075,355082..355084)
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /note="Zn binding sites [ion binding]; other site"
                     /db_xref="CDD:199908"
     misc_feature    355097..355483
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /note="C-terminal substrate binding domain of DnaJ and
                     HSP40; Region: DnaJ_C; cd10747"
                     /db_xref="CDD:199909"
     misc_feature    order(355295..355300,355307..355312,355370..355381,
                     355469..355483)
                     /gene="dnaJ"
                     /locus_tag="COSY_0347"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:199909"
     gene            complement(355980..356588)
                     /gene="ruvA"
                     /locus_tag="COSY_0348"
                     /db_xref="GeneID:5172269"
     CDS             complement(355980..356588)
                     /gene="ruvA"
                     /locus_tag="COSY_0348"
                     /codon_start=1
                     /transl_table=11
                     /product="holliday junction DNA helicase RuvA"
                     /protein_id="YP_001219197.1"
                     /db_xref="GI:148244503"
                     /db_xref="GeneID:5172269"
                     /translation="MVMIGKLSGTILEKNPPEILLEVDKIGYEILCSMSSFYAMGDEE
                     QLSLYTHLSIKENAHILYGFISKDEKTLFRELIRINGIGPKVALAILSHLDINSLIKV
                     ITDGNDTLLAKTPGIGIKTAQKLIVELKDRLEKLKLNNENHKNIHIKFKKNPNIKQAS
                     AALQALGFKARESEKMLSVIKDNSLSTKALIRQALQNKESFI"
     misc_feature    complement(356001..356582)
                     /gene="ruvA"
                     /locus_tag="COSY_0348"
                     /note="Holliday junction DNA helicase RuvA; Reviewed;
                     Region: ruvA; PRK00116"
                     /db_xref="CDD:234645"
     misc_feature    complement(356400..356582)
                     /gene="ruvA"
                     /locus_tag="COSY_0348"
                     /note="RuvA N terminal domain; Region: RuvA_N; pfam01330"
                     /db_xref="CDD:216437"
     misc_feature    complement(356001..356117)
                     /gene="ruvA"
                     /locus_tag="COSY_0348"
                     /note="RuvA, C-terminal domain; Region: RuvA_C; pfam07499"
                     /db_xref="CDD:219432"
     gene            complement(356579..357193)
                     /gene="leuD"
                     /locus_tag="COSY_0349"
                     /db_xref="GeneID:5172008"
     CDS             complement(356579..357193)
                     /gene="leuD"
                     /locus_tag="COSY_0349"
                     /EC_number="4.2.1.33"
                     /note="catalyzes the isomerization between
                     2-isopropylmalate and 3-isopropylmalate in leucine
                     biosynthesis; forms a heterodimer of LeuC/D"
                     /codon_start=1
                     /transl_table=11
                     /product="isopropylmalate isomerase small subunit"
                     /protein_id="YP_001219198.1"
                     /db_xref="GI:148244504"
                     /db_xref="GeneID:5172008"
                     /translation="MQKFTTFTSIAIPLKRANIDTDAIIPKQFLKSIKRSGFGANLFD
                     EWRYLDHGEIGMDNSKRPLNMDFVLNQPKYQNAKILLVLKNFGCGSSREHAPWALKDY
                     GFKTIIAPSFADIFYNNCFKNGILPIVQNNNVMDELFSSTDKITINLDAQSININNKN
                     YPFEIDIERKTHLINGLDDISLTLQYINDIKAFEKHYFNKYDWL"
     misc_feature    complement(356582..357193)
                     /gene="leuD"
                     /locus_tag="COSY_0349"
                     /note="isopropylmalate isomerase small subunit;
                     Provisional; Region: leuD; PRK01641"
                     /db_xref="CDD:179314"
     misc_feature    complement(356747..357154)
                     /gene="leuD"
                     /locus_tag="COSY_0349"
                     /note="Aconatase-like swivel domain of 3-isopropylmalate
                     dehydratase and related uncharacterized proteins.
                     3-isopropylmalate dehydratase catalyzes the isomerization
                     between 2-isopropylmalate and 3-isopropylmalate, via the
                     formation of 2-isopropylmaleate...; Region: IPMI_Swivel;
                     cd01577"
                     /db_xref="CDD:238809"
     misc_feature    complement(356918..356926)
                     /gene="leuD"
                     /locus_tag="COSY_0349"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238809"
     gene            complement(357194..358594)
                     /gene="leuC"
                     /locus_tag="COSY_0350"
                     /db_xref="GeneID:5172591"
     CDS             complement(357194..358594)
                     /gene="leuC"
                     /locus_tag="COSY_0350"
                     /EC_number="4.2.1.33"
                     /note="dehydratase component, catalyzes the isomerization
                     between 2-isopropylmalate and 3-isopropylmalate"
                     /codon_start=1
                     /transl_table=11
                     /product="isopropylmalate isomerase large subunit"
                     /protein_id="YP_001219199.1"
                     /db_xref="GI:148244505"
                     /db_xref="GeneID:5172591"
                     /translation="MAKTLYNKLMDAHIIRENISTALIYIDRHLIHEVTSPQAFEGLS
                     IANRKLWRKSTNLAVPDHNVPTTNRSSGVSSISDPISRIQIETLGRNCELFGIDEISM
                     NDTRQGIVHIIGPEQGATFPGMSIVCGDSHTSTHGALGALAFGIGTSEVEHVLATNCL
                     WQSKSKNFNIEVNGSLNQHVSAKDIALYIIGQLGTAGGMGFAIEFSGNTIQNLSIEGR
                     MTLCNMAIEAGARIGMVAVDEKTINYVKDRPLAPSGIKWRKAVKYWRTLHSDKNAHFD
                     KTMHFDAKDIKPQVTWGTSPDMVVATDGYVPNPNNAKNQTEKISWKNALNYMHLNANT
                     KISDIKIDKIFIGSCTNSRIEDLRIAADILKDKKIANNIKLALVVPGSGIIKKQAEEE
                     ELDKIFINSGFEWREAGCSMCLAMNADKLEVGERCASTSNRNFEGRQGQGSFTHLVSP
                     AIAASSAIAGYLSEVK"
     misc_feature    complement(357206..358594)
                     /gene="leuC"
                     /locus_tag="COSY_0350"
                     /note="3-isopropylmalate dehydratase large subunit;
                     Reviewed; Region: PRK00402"
                     /db_xref="CDD:234748"
     misc_feature    complement(357209..358513)
                     /gene="leuC"
                     /locus_tag="COSY_0350"
                     /note="3-isopropylmalate dehydratase catalyzes the
                     isomerization between 2-isopropylmalate and
                     3-isopropylmalate; Region: IPMI; cd01583"
                     /db_xref="CDD:153133"
     misc_feature    complement(order(357281..357283,357296..357298,
                     357353..357355,358202..358207,358490..358492,
                     358499..358501))
                     /gene="leuC"
                     /locus_tag="COSY_0350"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:153133"
     misc_feature    complement(order(357299..357301,357353..357358,
                     357365..357367,357548..357550,358199..358201))
                     /gene="leuC"
                     /locus_tag="COSY_0350"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:153133"
     gene            358649..360421
                     /gene="asnB"
                     /locus_tag="COSY_0351"
                     /db_xref="GeneID:5172686"
     CDS             358649..360421
                     /gene="asnB"
                     /locus_tag="COSY_0351"
                     /EC_number="6.3.5.4"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthetase (glutamine-hydrolyzing)"
                     /protein_id="YP_001219200.1"
                     /db_xref="GI:148244506"
                     /db_xref="GeneID:5172686"
                     /translation="MCGLCGQLRFDNRVVSDDRLKKMMKRMVHRGPDSSGSWIDGHIG
                     FGHQRLAIIDLSNNAYQPMIDKNLGLVLVFNGTIYNYQALHKYLIKQGYQFFSHSDTE
                     VIIKAYHHWGEDCVMHLDGMFAFCVWDKVQDQLFVARDRMGIKPFYFNLTDKAFSFAS
                     NVQALVTQEVDKSINSVALQQQLSLHGVVPAPNTIINGVNKIKPATTLTISGKGKVVE
                     KTYWHPKSIRLKEALTDEQFIQRTHELLRDSVLKRMNATDVPIGVLLSGGLDSSLLVA
                     LIKEIGYNNIRTFSIGFEDINGENGSEFEYSDQIVARFKTQHKKYMVSNSQVLTRLGE
                     AVANMSEPMVAQDAVAFYLLSEQVSKHIKVVLSGQGADEVFAGYFWYERMKAQTGSDI
                     ERFTKHYVDRPYEEYLQTVNLKYHSGNHTETWLHHEFTKENTDTFMDKVFRTDVTRLV
                     VDDPVKRVDNMTMAWGLEARMPFMDYKLVEHALSMSPSLKMLNKGKYPLKQIAKGLLP
                     DSVIDRKKSYFPMPALKYVQGEFLDFMSDILTSSKCINRGIFSQIFIAKIINKPQNYM
                     TPLNGSRLWHLALLEFWLQINIDE"
     misc_feature    358649..360403
                     /gene="asnB"
                     /locus_tag="COSY_0351"
                     /note="asparagine synthase family amidotransferase;
                     Region: trio_amidotrans; TIGR03104"
                     /db_xref="CDD:234108"
     misc_feature    358652..359317
                     /gene="asnB"
                     /locus_tag="COSY_0351"
                     /note="Glutamine amidotransferases class-II (GATase)
                     asparagine synthase_B type.  Asparagine synthetase B
                     catalyses the ATP-dependent conversion of aspartate to
                     asparagine. This enzyme is a homodimer, with each monomer
                     composed of a  glutaminase domain and a...; Region: AsnB;
                     cd00712"
                     /db_xref="CDD:238364"
     misc_feature    order(358652..358654,358793..358795,358871..358879,
                     358946..358948)
                     /gene="asnB"
                     /locus_tag="COSY_0351"
                     /note="active site"
                     /db_xref="CDD:238364"
     misc_feature    order(358697..358699,358721..358723,358730..358732,
                     358739..358753,358790..358792)
                     /gene="asnB"
                     /locus_tag="COSY_0351"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238364"
     misc_feature    359378..360214
                     /gene="asnB"
                     /locus_tag="COSY_0351"
                     /note="The C-terminal domain of Asparagine Synthase B.
                     This domain is always found associated n-terminal
                     amidotransferase domain. Family members that contain this
                     domain catalyse the conversion of aspartate to asparagine.
                     Asparagine synthetase B  catalyzes the...; Region:
                     Asn_Synthase_B_C; cd01991"
                     /db_xref="CDD:238949"
     misc_feature    order(359438..359446,359519..359527,359708..359710,
                     359747..359755)
                     /gene="asnB"
                     /locus_tag="COSY_0351"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238949"
     misc_feature    order(359438..359446,359519..359527,359708..359710,
                     359747..359755)
                     /gene="asnB"
                     /locus_tag="COSY_0351"
                     /note="Molecular Tunnel; other site"
                     /db_xref="CDD:238949"
     gene            360411..360857
                     /gene="rnhA"
                     /locus_tag="COSY_0352"
                     /db_xref="GeneID:5172268"
     CDS             360411..360857
                     /gene="rnhA"
                     /locus_tag="COSY_0352"
                     /EC_number="3.1.26.4"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H"
                     /protein_id="YP_001219201.1"
                     /db_xref="GI:148244507"
                     /db_xref="GeneID:5172268"
                     /translation="MMNRIVIYTDGGCRCNTGIGGWGVWLKYGDYDKKLKGNEKKTTN
                     NRMELTATIKALEEIKSNQIGIDLFTDSKYVITGINEWMKNWKVKNWETSKKRPVKNV
                     DLWQRLDVLNKQHDVIWYWVKSHSNNKGNDIADELANLAMDKISLS"
     misc_feature    360420..360839
                     /gene="rnhA"
                     /locus_tag="COSY_0352"
                     /note="RNase HI family found mainly in prokaryotes;
                     Region: RNase_HI_prokaryote_like; cd09278"
                     /db_xref="CDD:187702"
     misc_feature    order(360438..360449,360537..360545,360552..360554,
                     360621..360623,360771..360773,360825..360827)
                     /gene="rnhA"
                     /locus_tag="COSY_0352"
                     /note="RNA/DNA hybrid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:187702"
     misc_feature    order(360438..360440,360552..360554,360621..360623,
                     360813..360815)
                     /gene="rnhA"
                     /locus_tag="COSY_0352"
                     /note="active site"
                     /db_xref="CDD:187702"
     gene            complement(360984..361415)
                     /locus_tag="COSY_0353"
                     /db_xref="GeneID:5172546"
     CDS             complement(360984..361415)
                     /locus_tag="COSY_0353"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoketide cyclase/lipid transport protein"
                     /protein_id="YP_001219202.1"
                     /db_xref="GI:148244508"
                     /db_xref="GeneID:5172546"
                     /translation="MHHISKNAIVSYSCKQMYQLINQVNQYPEFLNWCSDSSILKQSD
                     NQIIASIKINKGGFNQTFTTTNTLIPYQRIDMQLKEGLFKQLNGSWVFVALNNTACKI
                     QLNLAFSFSSKLVDISISHIFTSIANSQLDAFIVRAKTIYG"
     misc_feature    complement(360993..361406)
                     /locus_tag="COSY_0353"
                     /note="Coenzyme Q-binding protein COQ10p and similar
                     proteins; Region: COQ10p_like; cd07813"
                     /db_xref="CDD:176855"
     misc_feature    complement(order(361014..361016,361023..361031,
                     361035..361043,361047..361061,361092..361094,
                     361098..361100,361104..361106,361110..361112,
                     361140..361142,361146..361148,361152..361157,
                     361188..361190,361194..361196,361212..361214,
                     361218..361220,361224..361226,361257..361259,
                     361263..361265,361269..361271,361275..361277,
                     361305..361307,361350..361355,361359..361367,
                     361392..361394,361398..361400,361404..361406))
                     /locus_tag="COSY_0353"
                     /note="putative coenzyme Q binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:176855"
     gene            361430..361915
                     /gene="smpB"
                     /locus_tag="COSY_0354"
                     /db_xref="GeneID:5172176"
     CDS             361430..361915
                     /gene="smpB"
                     /locus_tag="COSY_0354"
                     /note="binds to ssrA RNA (tmRNA) and is required for its
                     successful binding to ribosomes; also appears to function
                     in the trans-translation step by promoting accommodation
                     of tmRNA into the ribosomal A site; SmpB protects the
                     tmRNA from RNase R degradation in Caulobacter crescentus;
                     both the tmRNA and SmpB are regulated in cell
                     cycle-dependent manner; functions in release of stalled
                     ribosomes from damaged mRNAs and targeting proteins for
                     degradation"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein"
                     /protein_id="YP_001219203.1"
                     /db_xref="GI:148244509"
                     /db_xref="GeneID:5172176"
                     /translation="MAKKNKKISLNTIAFNKKARHVYFIEQTLEAGLSLEGWEVKSLR
                     DSKVQIKESYVILRSNEIFLYGAHISPLKSVSTHVNSDPIRTRKLLLNRLEINRIKEK
                     INQKGATIVALKLYWIRGMVKLEIGLAKGKKSYDKRQDNKLRDWQRDKQRTLKQINYR
                     L"
     misc_feature    361475..361825
                     /gene="smpB"
                     /locus_tag="COSY_0354"
                     /note="Small protein B (SmpB) is a component of the
                     trans-translation system in prokaryotes for releasing
                     stalled ribosome from damaged messenger RNAs; Region:
                     SmpB; cd09294"
                     /db_xref="CDD:187755"
     misc_feature    order(361517..361534,361538..361543,361547..361552,
                     361559..361561,361610..361612,361697..361714,
                     361796..361798)
                     /gene="smpB"
                     /locus_tag="COSY_0354"
                     /note="SmpB-tmRNA interface; other site"
                     /db_xref="CDD:187755"
     gene            362435..362860
                     /gene="ndk"
                     /locus_tag="COSY_0355"
                     /db_xref="GeneID:5171925"
     CDS             362435..362860
                     /gene="ndk"
                     /locus_tag="COSY_0355"
                     /EC_number="2.7.4.6"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase"
                     /protein_id="YP_001219204.1"
                     /db_xref="GI:148244510"
                     /db_xref="GeneID:5171925"
                     /translation="MERTLSIIKPDAVAKNIIGKIYSRFEEAGFRIIASKMIHLDNDE
                     AGGFYAVHKDRPFYGELLEFMTSGPIIVQVLEGEDVVAKHREIMGDTNPKEANSGTIR
                     ADFARSLDENTVHGSDSLENAVIEIKYFFGKNDICSRTR"
     misc_feature    362438..362827
                     /gene="ndk"
                     /locus_tag="COSY_0355"
                     /note="Nucleoside diphosphate kinase Group I
                     (NDPk_I)-like: NDP kinase domains are present in a large
                     family of structurally and functionally conserved proteins
                     from bacteria to humans that generally catalyze the
                     transfer of gamma-phosphates of a nucleoside...; Region:
                     NDPk_I; cd04413"
                     /db_xref="CDD:239876"
     misc_feature    order(362459..362461,362579..362581,362603..362605,
                     362687..362689,362705..362707,362738..362740,
                     362768..362770,362777..362779,362783..362788,
                     362810..362812)
                     /gene="ndk"
                     /locus_tag="COSY_0355"
                     /note="active site"
                     /db_xref="CDD:239876"
     misc_feature    order(362471..362473,362486..362494,362501..362503,
                     362510..362512,362537..362545)
                     /gene="ndk"
                     /locus_tag="COSY_0355"
                     /note="multimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239876"
     gene            362910..363980
                     /locus_tag="COSY_0356"
                     /db_xref="GeneID:5171965"
     CDS             362910..363980
                     /locus_tag="COSY_0356"
                     /note="radical SAM enzyme Cfr family"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-cluster redox enzyme"
                     /protein_id="YP_001219205.1"
                     /db_xref="GI:148244511"
                     /db_xref="GeneID:5171965"
                     /translation="MNKQNLLSLNQDALNDFFVCLGEKHYRTKQIMQWIYKVHEFDFD
                     KMFNFSKSLREELNKIACIEFPKVVKQKFALDKVIKWVLALSEDNYIEMVYIPEKDRG
                     TLCISSQVGCALACTFCSTGMQGFNKNLTTAEIIAQVLIANKYLNSKTKRISNIVFMG
                     MGEPLLNEQAVYNACDLLLDDLAFGLSRRKVTISTSGIVPSILRMSKRTPVSLAISLH
                     APNNQLRDKLVPVNQKYSIEELLKACKVYLNAGTQERHILFEYVMLKDVNDSTEHANK
                     LAKLLKAISAKVNLIPFNSFERTQYQSSNAQTIEKFQDILYQQGIRTMMRRTRGEDID
                     GACGQLAGKVLNKTKKLNARKH"
     misc_feature    362916..363959
                     /locus_tag="COSY_0356"
                     /note="Predicted Fe-S-cluster redox enzyme [General
                     function prediction only]; Region: COG0820"
                     /db_xref="CDD:223890"
     misc_feature    363240..>363665
                     /locus_tag="COSY_0356"
                     /note="Radical SAM superfamily. Enzymes of this family
                     generate radicals by combining a 4Fe-4S cluster and
                     S-adenosylmethionine (SAM) in close proximity. They are
                     characterized by a conserved CxxxCxxC motif, which
                     coordinates the conserved iron-sulfur cluster; Region:
                     Radical_SAM; cd01335"
                     /db_xref="CDD:100105"
     misc_feature    order(363243..363245,363249..363251,363255..363257,
                     363261..363269,363387..363389,363393..363398,
                     363489..363497,363555..363557)
                     /locus_tag="COSY_0356"
                     /note="FeS/SAM binding site; other site"
                     /db_xref="CDD:100105"
     gene            363964..364272
                     /locus_tag="COSY_0357"
                     /db_xref="GeneID:5172100"
     CDS             363964..364272
                     /locus_tag="COSY_0357"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219206.1"
                     /db_xref="GI:148244512"
                     /db_xref="GeneID:5172100"
                     /translation="MLESIDYYSKKSKKKLKLKCWLLLILVSNVGIFWYLNQKDNIKK
                     AKEVPALIVINHGEKEQKEVVSTVIINDYLLLNSGFNRNIINSKELDEIIYNYTNKLQ
                     "
     gene            364269..365345
                     /gene="ispG"
                     /locus_tag="COSY_0358"
                     /db_xref="GeneID:5172431"
     CDS             364269..365345
                     /gene="ispG"
                     /locus_tag="COSY_0358"
                     /EC_number="1.17.7.1"
                     /note="catalyzes the conversion of 2C-methyl-D-erythritol
                     2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl
                     diphosphate; involved in isoprenoid synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-en-1-yl diphosphate
                     synthase"
                     /protein_id="YP_001219207.1"
                     /db_xref="GI:148244513"
                     /db_xref="GeneID:5172431"
                     /translation="MKPIHTIHRRESKQIFVGNVAIGGDAPISVQSMTNTKTTDVKAT
                     LKQISEIEEAGADLVRVSIPTMEAARAFKVIKEQVTIPLIADIHFDYKIALEVAKYGA
                     DCLRINPGNIGRVDYISEVVASAKDHDIPIRIGVNAGSLEKYLQKKYTRPTPEAMVES
                     ALRHIDILDKLNFDNFKISLKASEIFMTVFAYQQLSSQIDNPLHLGITEAGSLSFGTV
                     KSSIGLGLLLSKGIGDTIRVSLASDPVDEVRVAFNILKSLNLRQKGVNLIACPSCSRQ
                     KFDVIKVVSELESRFKDIITPIDVSVIGCVVNGPGEAKSVSVGLTGGDPNLLYLDGKT
                     HSKIINENLVNELEAQVRNSLKNL"
     misc_feature    364269..365342
                     /gene="ispG"
                     /locus_tag="COSY_0358"
                     /note="4-hydroxy-3-methylbut-2-en-1-yl diphosphate
                     synthase; Reviewed; Region: ispG; PRK00366"
                     /db_xref="CDD:234737"
     misc_feature    364293..>365036
                     /gene="ispG"
                     /locus_tag="COSY_0358"
                     /note="4-hydroxy-3-methylbut-2-en-1-yl diphosphate
                     synthase; Validated; Region: PRK00694"
                     /db_xref="CDD:234812"
     misc_feature    <364998..365258
                     /gene="ispG"
                     /locus_tag="COSY_0358"
                     /note="4-hydroxy-3-methylbut-2-en-1-yl diphosphate
                     synthase; Validated; Region: PRK00694"
                     /db_xref="CDD:234812"
     gene            complement(365332..365826)
                     /locus_tag="COSY_0359"
                     /db_xref="GeneID:5172607"
     CDS             complement(365332..365826)
                     /locus_tag="COSY_0359"
                     /note="Similar to flagellar biosynthesis protein FlhF."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219208.1"
                     /db_xref="GI:148244514"
                     /db_xref="GeneID:5172607"
                     /translation="MKKLLKRYSPNLDELKNHKHLNWFGKRLYHSSLWNFNRRSISKA
                     FAIGLFCAFIPIPFQMLLAAPISIIFSANLPLSISLVWITNPITMPAIFYVCYKLGAW
                     LLGVNIKQDFAMSLEYIWQVFDIIWQPFLLGCLVISITSSVFGYFAIQFIYRYKVYKR
                     VKGF"
     misc_feature    complement(365341..365769)
                     /locus_tag="COSY_0359"
                     /note="Uncharacterized protein conserved in bacteria
                     (DUF2062); Region: DUF2062; pfam09835"
                     /db_xref="CDD:220432"
     gene            complement(365823..367625)
                     /gene="dxs"
                     /locus_tag="COSY_0360"
                     /db_xref="GeneID:5172363"
     CDS             complement(365823..367625)
                     /gene="dxs"
                     /locus_tag="COSY_0360"
                     /EC_number="2.2.1.7"
                     /note="1-deoxyxylulose-5-phosphate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="YP_001219209.1"
                     /db_xref="GI:148244515"
                     /db_xref="GeneID:5172363"
                     /translation="MLNSITSPTDIKQLNIVQLQSLAKKVRTFLIENIQRTGGHLAPN
                     LGIIEMTIAIHYIFDTPYDSLVFDVGHQAYTHKILTGRFDKMHTLRQKGGLSGFTKHS
                     ESEHDSFGAGHSSTSISAALGIAIGNSINNSKGKSIAVIGDGALTGGMSFEALNHAGD
                     SDADLLIILNDNDMSISKNVGAMNKYLTRLISGKVYSTMKSKSLGFLEKIPQIHKFAK
                     RSEEHLKGMVLPSTLFEELGLDYFGPIDGHDLPTLIQTLKNLKKQTKPRLLHIITKKG
                     YGLKIAENDPCKFHGVTPASSNTSSFPSYSTVFGTWLNNTALHHKNLVAITPAMCAGS
                     GMSEFEKNYPKQYFDVGIAEQHAITFAGGLAMQGLKPIVAIYSTFLQRGYDQLIHDIA
                     LQNLNVIFAIDRAGLVGADGATHAGSFDLSFLRCIPNLIIMTPSNAMQMYQMFNTAFK
                     TNNTICIRYPRGVSNIQDYVTDKQISLGKAKIILKGSDVAIFAFGTTVESAFSAGKKL
                     NATVVDMRFVKPLDKDLITELANSHIKLISIEDNAAIGGAGSAISELLHQRNINTSLS
                     ILGLPDKFSEQGEQKELYDLYGLNEAGILNAARS"
     misc_feature    complement(365826..367625)
                     /gene="dxs"
                     /locus_tag="COSY_0360"
                     /note="1-deoxy-D-xylulose-5-phosphate synthase;
                     Provisional; Region: PRK05444"
                     /db_xref="CDD:235470"
     misc_feature    complement(366789..367514)
                     /gene="dxs"
                     /locus_tag="COSY_0360"
                     /note="Thiamine pyrophosphate (TPP) family, DXS subfamily,
                     TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate
                     synthase (DXS) is a regulatory enzyme of the
                     mevalonate-independent pathway involved in terpenoid
                     biosynthesis. Terpeniods are plant natural products...;
                     Region: TPP_DXS; cd02007"
                     /db_xref="CDD:238965"
     misc_feature    complement(order(367104..367106,367110..367112,
                     367191..367202,367284..367286))
                     /gene="dxs"
                     /locus_tag="COSY_0360"
                     /note="TPP-binding site; other site"
                     /db_xref="CDD:238965"
     misc_feature    complement(366243..366704)
                     /gene="dxs"
                     /locus_tag="COSY_0360"
                     /note="Pyrimidine (PYR) binding domain of
                     1-deoxy-D-xylulose-5-phosphate synthase (DXS),
                     transketolase (TK), and related proteins; Region:
                     TPP_PYR_DXS_TK_like; cd07033"
                     /db_xref="CDD:132916"
     misc_feature    complement(order(366270..366272,366333..366338,
                     366384..366386,366393..366395,366468..366473,
                     366480..366482,366534..366542,366546..366551,
                     366558..366575,366579..366581,366588..366590,
                     366639..366641,366657..366659,366663..366665))
                     /gene="dxs"
                     /locus_tag="COSY_0360"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    complement(order(366342..366344,366348..366353,
                     366357..366362,366387..366389,366393..366395,
                     366474..366476,366480..366485,366564..366572,
                     366579..366581,366639..366641))
                     /gene="dxs"
                     /locus_tag="COSY_0360"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    complement(order(366480..366482,366489..366491,
                     366564..366566,366570..366572))
                     /gene="dxs"
                     /locus_tag="COSY_0360"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    complement(365844..366194)
                     /gene="dxs"
                     /locus_tag="COSY_0360"
                     /note="Transketolase, C-terminal domain; Region:
                     Transketolase_C; pfam02780"
                     /db_xref="CDD:217227"
     gene            complement(367688..369043)
                     /locus_tag="COSY_0361"
                     /db_xref="GeneID:5172453"
     CDS             complement(367688..369043)
                     /locus_tag="COSY_0361"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="YP_001219210.1"
                     /db_xref="GI:148244516"
                     /db_xref="GeneID:5172453"
                     /translation="MNRPELLSPAGSLKHMRYAYAYGADAVYAGQPRYSLRVRNNLFD
                     TKTLKQGILEAHANNKKFFIASNIIPHNSKIKTYIKDIEPIINLGPDALIMADPGLIM
                     MVKEKFPNQVIHLSVQANSINYATVKFWKNTGVSRIILSRELSLDEIKDIRQECPDVE
                     LEVFVHGSLCIAYSGRCLLSGYFNHRDPNQGSCTNSCRWKYDVKKAKETFKGDVKAVK
                     IKTPENQVVLLEEQTRLGELMPTFEDEHGTYIMNSKDLRAIEHVHTLTTIGINSLKIE
                     GRTKSHYYVARTTQVYRQAIDDAVAGREFNKDAFGILENLANRGYTDGFYQRHQPEEL
                     QTYFENYSRSNKQQVVGEILDYKDGKAFIKVKNKFSVGNSIEVILPDRCFNTTIEYIL
                     TKHNEKLDVAKGSGYQVWIPMREIKPELGFIAKNFNEKIKIKNKNIKKDHSLKIRRPS
                     W"
     misc_feature    complement(367799..369043)
                     /locus_tag="COSY_0361"
                     /note="putative protease; Provisional; Region: PRK15452"
                     /db_xref="CDD:237969"
     misc_feature    complement(368057..368821)
                     /locus_tag="COSY_0361"
                     /note="Peptidase family U32; Region: Peptidase_U32;
                     pfam01136"
                     /db_xref="CDD:216321"
     gene            369102..369689
                     /locus_tag="COSY_0362"
                     /db_xref="GeneID:5172359"
     CDS             369102..369689
                     /locus_tag="COSY_0362"
                     /note="methyltransferase small domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219211.1"
                     /db_xref="GI:148244517"
                     /db_xref="GeneID:5172359"
                     /translation="MFTKKDIPRLKQDLTIETNLLGVNLTLKTRWGVFSPRSIDDGTK
                     LFMKYLKIINDDKCLDLGCGYGPIGLAVAKSCPKTEVHMVDKDFIAVELSNINAKLNR
                     IDNIQVYLSDAFLSVNKTDYFDQVLSNVPAKVGREQLSIILYDAYDVLKPGGKITFVS
                     INSLRHFIKNNFKFVFGNYKKLKQGQKYTVSQAIK"
     misc_feature    <369105..369686
                     /locus_tag="COSY_0362"
                     /note="16S RNA G1207 methylase RsmC [Translation,
                     ribosomal structure and biogenesis]; Region: RsmC;
                     COG2813"
                     /db_xref="CDD:225370"
     misc_feature    369270..369569
                     /locus_tag="COSY_0362"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(369282..369302,369354..369359,369432..369440,
                     369486..369488)
                     /locus_tag="COSY_0362"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            369759..370088
                     /locus_tag="COSY_0363"
                     /db_xref="GeneID:5172343"
     CDS             369759..370088
                     /locus_tag="COSY_0363"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-related protein"
                     /protein_id="YP_001219212.1"
                     /db_xref="GI:148244518"
                     /db_xref="GeneID:5172343"
                     /translation="MDVMDRIQHQVDSAAVVLYMKGTPQFPQCGFSAKAAQTLTSTGV
                     EFAYVNIFEDQEVFQSLPTFANWPTFPQIYFNSELVGGGDIIVEMAEMGTLKDEMKKA
                     SEKFDVK"
     misc_feature    369777..370046
                     /locus_tag="COSY_0363"
                     /note="Glutaredoxin (GRX) family, PKC-interacting cousin
                     of TRX (PICOT)-like subfamily; composed of PICOT and
                     GRX-PICOT-like proteins. The non-PICOT members of this
                     family contain only the GRX-like domain, whereas PICOT
                     contains an N-terminal TRX-like domain...; Region:
                     GRX_PICOT_like; cd03028"
                     /db_xref="CDD:239326"
     misc_feature    order(369819..369821,369843..369851,369963..369968)
                     /locus_tag="COSY_0363"
                     /note="putative GSH binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239326"
     misc_feature    order(369843..369845,369852..369854)
                     /locus_tag="COSY_0363"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239326"
     gene            complement(370160..373984)
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /db_xref="GeneID:5172346"
     CDS             complement(370160..373984)
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /EC_number="6.3.5.3"
                     /note="catalyzes the formation of
                     2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from
                     N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and
                     L-glutamine in purine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="YP_001219213.1"
                     /db_xref="GI:148244519"
                     /db_xref="GeneID:5172346"
                     /translation="MIKTIQHIQALSTFKKDTLNKKIAFLGVNLIGIEYIHFADCENT
                     LSSSKLLTLEKLLSYEAHIKINNSVQIIIIPRLGTISPWSSKVSNILHLCGLEKIRRI
                     ERGIIYHFDKISDNKADILAIIMDKMTESELDSIDNMYLIFNKLKAKSLSSIDILNGG
                     KSALERSNIELNLSLSDSEISYLNENFTHLKRNPNDIELMMFTQINSEHCRHKIFNAD
                     WIIDDIAQEKSLFSMIRNTYHQNPKGLLSVYSDNSAVMEGYQGERFYANENNEYVSTQ
                     EHRAILMKVETHNHPTAIAPYQGAATGSGGEIRDEGSTGQGSKPKVGLCGFSVSNLKI
                     KNAKQPWEIEHGKPNQIQSALDIILEAPIGVASFNNEFGRPNILGYFRTFEQQMPNGD
                     IRGYHKPIMLAGGLGHIQRRHIKKGNIPVGSKIIVLGGPSMLIGLGGSVASSIKSDKQ
                     NEDLNFASVQRANPEMQRRAQEVIDQCTNLEENNPIISIHDIGAGGLSNGLPELINDS
                     SRGGKFQLRAIPNDDNQMSPLEIWCNESQERYVLAISEKNLNVFTDICKRERSPFAVL
                     GETTKEQILVLNDKLFNNIPINIPMTVLLGNPPKTSINAKSSTNILNILDTSNIKLDD
                     AITRIVQLPSVASKNFLITIGDRSVTGMVARDQFIGPWQVPVSDCAISIADYVGFNGE
                     IMSLGERAPLALCDARCAARMTIGEALTNMLGGYVEDIQHINLSANWMSASGHENEDV
                     KLFQAVKAVGMELCPKLGLTIPVGKDSMNMKSTWKDNDINKSVTAPLSLIITAFSKTS
                     DVRLQLTPLLENTQESELLLIDLGFGQNRMGGSCIAQVYNQIGNIAPNLDKETTFKKF
                     FTVINQFNKNGLISAYHDRSDGGVIVTLLEIAFASHCGLDINFNGEIEELFNEELGCV
                     IQVKNKNKQTVMKALDKIGLSNFTRTIALINNTDMIKISSNDNLIYNKPRAELQELWS
                     STSYKIAKLRDNPNCAKEEFSSISERTSGIKIDLNFNINKSISAPYIKIPTKPKIAIL
                     REQGIHGQIEMGVAFTKAQFSAIDVHMNDILSGKVSLVDFKGLVACGGFSYGDVLGAG
                     RGWAGSILYNERAKDEFEAFFNRNDSFALGVCNGCQMMSNLTQIIPDSEHFPTFKRNT
                     SEQFEARFSSVQIKPSNSIFFKEMEGSIIPISIAHGEGRASFALQMNKNYSIMQYVDH
                     DGKPTQNYPHNPNGSDFATAGVTNKSGQVTIMMPHPERVIRSVQNSYHPKYWRERGPW
                     IRMFENARAWVD"
     misc_feature    complement(370163..373981)
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /note="phosphoribosylformylglycinamidine synthase;
                     Provisional; Region: PRK05297"
                     /db_xref="CDD:235394"
     misc_feature    complement(372218..373393)
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /note="PurL subunit of the formylglycinamide
                     ribonucleotide amidotransferase (FGAR-AT), first repeat.
                     FGAR-AT catalyzes the ATP-dependent conversion of
                     formylglycinamide ribonucleotide (FGAR) and glutamine to
                     formylglycinamidine ribonucleotide (FGAM), ADP; Region:
                     PurL_repeat1; cd02203"
                     /db_xref="CDD:100034"
     misc_feature    complement(order(372773..372775,372785..372790,
                     372845..372847,373001..373003,373010..373012,
                     373019..373021,373055..373057,373130..373132,
                     373136..373147))
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100034"
     misc_feature    complement(order(372845..372853,373055..373057,
                     373067..373069))
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:100034"
     misc_feature    complement(371192..371983)
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /note="PurL subunit of the formylglycinamide
                     ribonucleotide amidotransferase (FGAR-AT), second repeat.
                     FGAR-AT catalyzes the ATP-dependent conversion of
                     formylglycinamide ribonucleotide (FGAR) and glutamine to
                     formylglycinamidine ribonucleotide (FGAM), ADP; Region:
                     PurL_repeat2; cd02204"
                     /db_xref="CDD:100035"
     misc_feature    complement(order(371609..371611,371621..371626,
                     371690..371692,371795..371797,371804..371806,
                     371813..371815,371852..371854,371927..371929,
                     371933..371944))
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100035"
     misc_feature    complement(order(371690..371698,371852..371854,
                     371864..371866))
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:100035"
     misc_feature    complement(370175..370906)
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /note="Type 1 glutamine amidotransferase (GATase1)-like
                     domain found in Formylglycinamide ribonucleotide
                     amidotransferase; Region: GATase1_FGAR_AT; cd01740"
                     /db_xref="CDD:153211"
     misc_feature    complement(order(370259..370270,370274..370276,
                     370442..370447,370613..370615,370625..370627,
                     370736..370738,370748..370753))
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /note="putative active site [active]"
                     /db_xref="CDD:153211"
     misc_feature    complement(order(370262..370264,370268..370270,
                     370625..370627))
                     /gene="purL"
                     /locus_tag="COSY_0364"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153211"
     gene            complement(374121..374861)
                     /locus_tag="COSY_0365"
                     /db_xref="GeneID:5172577"
     CDS             complement(374121..374861)
                     /locus_tag="COSY_0365"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219214.1"
                     /db_xref="GI:148244520"
                     /db_xref="GeneID:5172577"
                     /translation="MAGHSKWHNIQHRKGIQDVKRGKIFAKFIKEIIIATKTGGSVIE
                     NNPSLRMVIDRALAANMKRNTIENAVKRGSCDLDDKNYDEVRYEGYGLAGTAIIVDTL
                     TDNRNRTVANIRHAFSKYGGNLSIEGSVSYLFIKQGFINFETGDEEQIMEVALDAGAK
                     DIITNDNGSIYVITTTEDFFTIRNTLITARLEPSHSEVTMKPINYIKLNLHNTEKFIK
                     LTDSLKDLDDTREVYHNADISDEIITQF"
     misc_feature    complement(374124..374861)
                     /locus_tag="COSY_0365"
                     /note="hypothetical protein; Validated; Region: PRK00110"
                     /db_xref="CDD:234640"
     gene            complement(374890..375840)
                     /gene="nadA"
                     /locus_tag="COSY_0366"
                     /db_xref="GeneID:5172362"
     CDS             complement(374890..375840)
                     /gene="nadA"
                     /locus_tag="COSY_0366"
                     /note="3 different subfamilies; catalyzes the formation of
                     quinolinate from iminoaspartate and dihydroxyacetone
                     phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthetase"
                     /protein_id="YP_001219215.1"
                     /db_xref="GI:148244521"
                     /db_xref="GeneID:5172362"
                     /translation="MLSIQEKIKTALKAHNAILVAHYYVDAKLQTLAEETGGIVSDSL
                     EMARFSQNCDADIIIVAGVKFMGETAKILSPEKTVLILDDNATCSLDEDCPIDEFSKF
                     CDEHSNRTVVVYANTSAQVKAKADWVVTSGSALNVVKYLKDKGKKILWAPDKHLGNYV
                     KNKTGVDMLLWQGACLVHERFKAKALIQLQNIYPEAATLVHPESPQEVVDLADVIGST
                     TTLINAVKNRKEQTFIVATDNGIFHKMHEVAPNKKLIEAPTMGESADCESCAHCQWMA
                     MNTLDNCLDAIQNKTHEIIIDQSIVIQAKKSIHKLLNFTI"
     misc_feature    complement(374896..375840)
                     /gene="nadA"
                     /locus_tag="COSY_0366"
                     /note="quinolinate synthetase; Provisional; Region:
                     PRK09375"
                     /db_xref="CDD:236489"
     gene            complement(375847..377601)
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /db_xref="GeneID:5172016"
     CDS             complement(375847..377601)
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /EC_number="6.1.1.12"
                     /note="catalyzes a two-step reaction, first charging an
                     aspartate molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; contains discriminating
                     and non-discriminating subtypes"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-tRNA synthetase"
                     /protein_id="YP_001219216.1"
                     /db_xref="GI:148244522"
                     /db_xref="GeneID:5172016"
                     /translation="MIRTHYCGKINTSDVGQIIEIYGWVNRKRNHGGVIFLDIRDIRG
                     IVQVVINPDNKDFSLAETIRNEFVLKISGLVIARDKGLSNPKLVSGEIEIKAQNIEIL
                     NTSKPTPFQINAINTSEEIRLRYRYLDLRNNAMQKRLHLRSRVTHYIRKFMDKHDFLD
                     IETPFLTKATPEGARDYLVPSRTHPGKFFALPQSPQLFKQLLMMSGFERYYQIVKCFR
                     DEDLRADRQPEFTQLDIETSFMNENEIMTIMERMTRGLFKSVINVDLGNKFPTITYED
                     AMEKYGLDCPDIRIPIQIISIDKLMKNVDFKVFSKPANNSNSRVAALKISGGASISRK
                     NIDKYTKYVGIYGAKGLAYIKLNKNGPTSPILKFLDDEITNKIIEITGAKTGDIIFFG
                     ADKTKIVNESLGNLREKIAKDLNLFDTQWAPIWVVDFPMFGINDNGSLNATHHPFTAP
                     IVDKETLKQTAKTAFSRAYDLVINGSEIGGGSIRIHQVEMQKTVLKLLGISNQEAQDK
                     FGFLLDALEYGCPPHGGMAFGLDRLVMIMTGTDNIRDVIAFPKTQTATCLLTDAPANV
                     PKKLLRELNVKISLPKKN"
     misc_feature    complement(375856..377601)
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="aspartyl-tRNA synthetase; Validated; Region: aspS;
                     PRK00476"
                     /db_xref="CDD:234775"
     misc_feature    complement(377239..377595)
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="EcAspRS_like_N: N-terminal, anticodon recognition
                     domain of the type found in Escherichia coli aspartyl-tRNA
                     synthetase (AspRS), the human mitochondrial (mt) AspRS-2,
                     the discriminating (D) Thermus thermophilus AspRS-1, and
                     the nondiscriminating (ND)...; Region: EcAspRS_like_N;
                     cd04317"
                     /db_xref="CDD:239812"
     misc_feature    complement(order(377284..377289,377293..377295,
                     377476..377478,377530..377532,377584..377586,
                     377593..377595))
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239812"
     misc_feature    complement(order(377275..377277,377323..377325,
                     377350..377352,377368..377370,377410..377412,
                     377461..377463,377494..377496,377509..377517,
                     377521..377523))
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:239812"
     misc_feature    complement(<376747..377187)
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="Asp tRNA synthetase (aspRS) class II core domain.
                     Class II assignment is based upon its structure and the
                     presence of three characteristic sequence motifs. AspRS is
                     a homodimer, which attaches a specific amino acid to the
                     3&apos; OH group of ribose of...; Region: AspRS_core;
                     cd00777"
                     /db_xref="CDD:238400"
     misc_feature    complement(order(376870..376872,376885..376887,
                     376915..376917,376945..376947,376957..376959,
                     376975..376980,376987..376992,377035..377046,
                     377056..377070,377077..377079,377098..377118,
                     377122..377133,377140..377142,377149..377154,
                     377161..377163,377170..377178))
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238400"
     misc_feature    complement(377098..377112)
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="motif 1; other site"
                     /db_xref="CDD:238400"
     misc_feature    complement(order(376906..376908,376912..376914,
                     376921..376929,376942..376944,376948..376950,
                     377005..377007,377014..377016,377020..377022,
                     377080..377088))
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="active site"
                     /db_xref="CDD:238400"
     misc_feature    complement(376942..376953)
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="motif 2; other site"
                     /db_xref="CDD:238400"
     misc_feature    complement(376393..376677)
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="GAD domain; Region: GAD; pfam02938"
                     /db_xref="CDD:145868"
     misc_feature    complement(375943..>376341)
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="Class II tRNA amino-acyl synthetase-like catalytic
                     core domain. Class II amino acyl-tRNA synthetases (aaRS)
                     share a common fold and generally attach an amino acid to
                     the 3&apos; OH of ribose of the appropriate tRNA.   PheRS
                     is an exception in that it...; Region:
                     class_II_aaRS-like_core; cl00268"
                     /db_xref="CDD:241739"
     misc_feature    complement(order(376006..376008,376015..376020,
                     376024..376029,376156..376158,376168..376173))
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="active site"
                     /db_xref="CDD:238391"
     misc_feature    complement(order(376006..376008,376015..376017))
                     /gene="aspS"
                     /locus_tag="COSY_0367"
                     /note="motif 3; other site"
                     /db_xref="CDD:238391"
     gene            complement(377598..378209)
                     /locus_tag="COSY_0368"
                     /db_xref="GeneID:5172285"
     CDS             complement(377598..378209)
                     /locus_tag="COSY_0368"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219217.1"
                     /db_xref="GI:148244523"
                     /db_xref="GeneID:5172285"
                     /translation="MKRLRNYFISGLLFWIPLGLSIVVIKFFLELINNIVPFQYLPEA
                     LFNLNGTIPGSGIIWVILILLITGALVNNFIGRKLIQLWEKLLNKIPGFRSIYSALKQ
                     LSDTVLSPSGKSFKEAVLVEYPRKGMWTIAFQTSNYSGEVAKKIGKEVINIYVPTTPN
                     PTSGFFIMLAKNDVIELDMSVDEAFKLVISTGVITPIKEGQIK"
     misc_feature    complement(377622..378209)
                     /locus_tag="COSY_0368"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG2928"
                     /db_xref="CDD:225480"
     gene            complement(378266..379045)
                     /gene="map"
                     /locus_tag="COSY_0369"
                     /db_xref="GeneID:5172329"
     CDS             complement(378266..379045)
                     /gene="map"
                     /locus_tag="COSY_0369"
                     /EC_number="3.4.11.18"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine aminopeptidase"
                     /protein_id="YP_001219218.1"
                     /db_xref="GI:148244524"
                     /db_xref="GeneID:5172329"
                     /translation="MSITIKSKNEIGKMRMAGRLAANVIDMISPYVRAGISTNELDKI
                     CHNYIVNQQGAIAAPLNYHGFPKSICTSINHVVCHGIPGNRKLRTGDIINIDITIIKN
                     GFHGDTSKMFIIGKSSVKAQRICKIAQECLYIGIKQVKPGVHLGEIGKTIGAHANKNN
                     CAVVRDYCGHGIGTEFHAEPQVIHYDDGRLNISPILKAGMTFTIEPMINLGGFEVITS
                     KIDNWTVTTKDHTLSAQWEHTILVTENGCEILTLRDDEEPV"
     misc_feature    complement(378290..379015)
                     /gene="map"
                     /locus_tag="COSY_0369"
                     /note="Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also
                     known as methionyl aminopeptidase and Peptidase M.
                     Catalyzes release of N-terminal amino acids,
                     preferentially methionine, from peptides and arylamides;
                     Region: MetAP1; cd01086"
                     /db_xref="CDD:238519"
     misc_feature    complement(order(378335..378337,378431..378433,
                     378536..378538,378725..378727,378758..378760,
                     378809..378811))
                     /gene="map"
                     /locus_tag="COSY_0369"
                     /note="active site"
                     /db_xref="CDD:238519"
     gene            complement(379036..380064)
                     /locus_tag="COSY_0370"
                     /db_xref="GeneID:5172543"
     CDS             complement(379036..380064)
                     /locus_tag="COSY_0370"
                     /note="Similar to the N-terminal region of peptidase M48,
                     Ste24p (670 aa) in Nitrosococcus oceani ATCC 19707."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219219.1"
                     /db_xref="GI:148244525"
                     /db_xref="GeneID:5172543"
                     /translation="MDFRKHQDKAKKNTLIIWSLYLVLLLISSILISYTLFVGLNLAQ
                     FYQPEYQQYSLSEKFIAANQIVFQNQEQLLNFLRFSLMVLLAMISATAFGFFQKSNGH
                     KVALSFDGKLISDKNNELSIEEKQALNIVAEQALAANIPTPTLYIIPDNAINAFAAGK
                     TTQEAIIAITQGSMKSFNRTQLSGIIAHEIGHIVNHDIKLNIQISAFVFSFTVLFFLS
                     RVIFYQAAYNRRIDGRVKLLLLATAAIIALIGMMTVWFGRILQAAMSRQREYLADASA
                     IQFTRYPNGLVEAFEIIKGDATTTLKNPNAKEYAHAMLFSMGSKLFATHPPLDKRIKR
                     IQNKVSCQ"
     misc_feature    complement(379054..379818)
                     /locus_tag="COSY_0370"
                     /note="Peptidase family M48; Region: Peptidase_M48;
                     cl12018"
                     /db_xref="CDD:245838"
     gene            complement(380205..380813)
                     /locus_tag="COSY_0371"
                     /db_xref="GeneID:5172336"
     CDS             complement(380205..380813)
                     /locus_tag="COSY_0371"
                     /note="LemA family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219220.1"
                     /db_xref="GI:148244526"
                     /db_xref="GeneID:5172336"
                     /translation="MEFLIQNWLLVTIIIVLIIWITSIYNNLVSYKTQYQNGFEQISV
                     QLKRRLDLIGNLVDIAKKYMKHEKETLTTVTEARKELIQANKVAQKNPDKTNAMTNLA
                     SSQVALESAMNGFNLKMEAYPDLKANNNMIQLSEEIIATENRIASARQGYNDLVQKFN
                     EYKKSFPNILFTSIFGFSVDAQNLEFNESIEQLKQAPKNLFS"
     misc_feature    complement(380235..380744)
                     /locus_tag="COSY_0371"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: LemA; COG1704"
                     /db_xref="CDD:224618"
     gene            complement(381581..381656)
                     /locus_tag="COSY_t13"
                     /db_xref="GeneID:5329733"
     tRNA            complement(381581..381656)
                     /locus_tag="COSY_t13"
                     /product="tRNA-His"
                     /db_xref="GeneID:5329733"
     gene            complement(381679..381755)
                     /locus_tag="COSY_t14"
                     /db_xref="GeneID:5329760"
     tRNA            complement(381679..381755)
                     /locus_tag="COSY_t14"
                     /product="tRNA-Arg"
                     /db_xref="GeneID:5329760"
     gene            complement(381806..381882)
                     /locus_tag="COSY_t15"
                     /db_xref="GeneID:5329761"
     tRNA            complement(381806..381882)
                     /locus_tag="COSY_t15"
                     /product="tRNA-Pro"
                     /db_xref="GeneID:5329761"
     gene            complement(382510..383181)
                     /gene="dnaQ"
                     /locus_tag="COSY_0375"
                     /db_xref="GeneID:5172361"
     CDS             complement(382510..383181)
                     /gene="dnaQ"
                     /locus_tag="COSY_0375"
                     /EC_number="2.7.7.7"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III epsilon subunit"
                     /protein_id="YP_001219221.1"
                     /db_xref="GI:148244527"
                     /db_xref="GeneID:5172361"
                     /translation="MERLIVLDTETTGIKPSEGHRIIEIGCIEIIDRQITKNNKYHEY
                     IQPNRNVGDSVRIHGITDKFLTKKPKFKEVVEEFLAYIKETTLIIHNAPFDLGFLNHE
                     LKLIGINERIEDKCTIIDSLELSKQQRPGTLHNLDSLCRRFKIDSSARTVHGALLDVQ
                     ILAQVYLAMTGGQSTLFSNDKTINEQDNNTNNIVRINNAIGKIKIVYANKKELAAHAD
                     YFKKL"
     misc_feature    complement(382513..383175)
                     /gene="dnaQ"
                     /locus_tag="COSY_0375"
                     /note="DNA polymerase III, epsilon subunit,
                     Proteobacterial; Region: dnaQ_proteo; TIGR01406"
                     /db_xref="CDD:130473"
     misc_feature    complement(382672..383172)
                     /gene="dnaQ"
                     /locus_tag="COSY_0375"
                     /note="DEDDh 3&apos;-5&apos; exonuclease domain of the
                     epsilon subunit of Escherichia coli DNA polymerase III and
                     similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like;
                     cd06131"
                     /db_xref="CDD:99835"
     misc_feature    complement(order(382708..382710,382723..382725,
                     382732..382734,382774..382779,382897..382905,
                     382909..382914,383008..383013,383020..383025,
                     383140..383145,383149..383160))
                     /gene="dnaQ"
                     /locus_tag="COSY_0375"
                     /note="active site"
                     /db_xref="CDD:99835"
     misc_feature    complement(order(382708..382710,382723..382725,
                     382897..382899,383152..383154,383158..383160))
                     /gene="dnaQ"
                     /locus_tag="COSY_0375"
                     /note="catalytic site [active]"
                     /db_xref="CDD:99835"
     misc_feature    complement(order(382708..382710,382723..382725,
                     382732..382734,382774..382779,382900..382905,
                     382909..382914,383008..383013,383020..383025,
                     383140..383145,383149..383160))
                     /gene="dnaQ"
                     /locus_tag="COSY_0375"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99835"
     gene            383251..383583
                     /gene="rpoZ"
                     /locus_tag="COSY_0376"
                     /db_xref="GeneID:5172280"
     CDS             383251..383583
                     /gene="rpoZ"
                     /locus_tag="COSY_0376"
                     /EC_number="2.7.7.6"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase omega subunit"
                     /protein_id="YP_001219222.1"
                     /db_xref="GI:148244528"
                     /db_xref="GeneID:5172280"
                     /translation="MARVTVEDCLDHVENRFELVLIAAKRAHQLSSGGYKPLLNAGKD
                     KPTVVALREIEAGLIDSSILSEIYVIDEQLSAQQKVLDSVKMSEIKDELSVTAVDKVI
                     DEITEIEE"
     misc_feature    383251..383448
                     /gene="rpoZ"
                     /locus_tag="COSY_0376"
                     /note="DNA-directed RNA polymerase subunit omega;
                     Reviewed; Region: rpoZ; PRK00392"
                     /db_xref="CDD:234744"
     gene            complement(385459..386118)
                     /locus_tag="COSY_0377"
                     /db_xref="GeneID:5172440"
     CDS             complement(385459..386118)
                     /locus_tag="COSY_0377"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219223.1"
                     /db_xref="GI:148244529"
                     /db_xref="GeneID:5172440"
                     /translation="MENKSLFSSIALIITLIIGYFIHNNQVIQLNNKISNLKQEYNVK
                     QIAKFPVTIRNSDTLENLNKQLIKTHSELKKAQDKLSLETSKGHVLNDEILQINNARI
                     EIIDLKYLLTSIQKKLQTSDEKLKYLEGIFEEQNKNIITKNIAHIKKLKEASTSIVVT
                     GLIVPAIGIATLISYTSEEIQNYCNNIKNTMNLEYKVFGKVISLNKNMRINYLQQCLR
                     K"
     gene            complement(386160..387146)
                     /gene="hemB"
                     /locus_tag="COSY_0378"
                     /db_xref="GeneID:5172338"
     CDS             complement(386160..387146)
                     /gene="hemB"
                     /locus_tag="COSY_0378"
                     /EC_number="4.2.1.24"
                     /note="catalyzes the formation of porphobilinogen from
                     5-aminolevulinate"
                     /codon_start=1
                     /transl_table=11
                     /product="delta-aminolevulinic acid dehydratase"
                     /protein_id="YP_001219224.1"
                     /db_xref="GI:148244530"
                     /db_xref="GeneID:5172338"
                     /translation="MTILTHRPRRMRKHSYTRELMRENHLLTSDLIFPIFIIKGENKR
                     QNINSMPGIKRLSVDQLLIEVAELIELGIQAIALFPVVPPIKKSLDAKEAFNPDGLIQ
                     RAIYTVKQKYSNLAVITDVALDSFTTHGQDGLIDNNGYVLNDETNEVLVRQALSHAQA
                     GTDIVAPSDMMDGRIGAIRKALEKNGFIHTNILAYSAKYASHYYDPFRDAIDSSANLG
                     ESNKKTYQMDPANSNEAIREVALDIDEGADIIMIKPGLPYLDIVYRIKQNFNIPIFAY
                     HVSGEYAMLKAAVQNNWLKEEQVVLETLLAFKRAGADGILTYYAKQVAKWLM"
     misc_feature    complement(386166..387131)
                     /gene="hemB"
                     /locus_tag="COSY_0378"
                     /note="Porphobilinogen synthase (PBGS), which is also
                     called delta-aminolevulinic acid dehydratase (ALAD),
                     catalyzes the condensation of two 5-aminolevulinic acid
                     (ALA) molecules to form the pyrrole porphobilinogen (PBG),
                     which is the second step in the...; Region:
                     ALAD_PBGS_aspartate_rich; cd04823"
                     /db_xref="CDD:240127"
     misc_feature    complement(order(386220..386222,386229..386231,
                     386241..386243,386250..386252,386295..386297,
                     386367..386381,386433..386438,386445..386447,
                     386454..386465,386472..386477,386538..386546,
                     386631..386636,386715..386720,386994..386996,
                     387003..387005,387075..387083,387108..387113,
                     387120..387128))
                     /gene="hemB"
                     /locus_tag="COSY_0378"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:240127"
     misc_feature    complement(order(386421..386423,386433..386435,
                     386631..386633,387126..387128))
                     /gene="hemB"
                     /locus_tag="COSY_0378"
                     /note="allosteric magnesium binding site [ion binding];
                     other site"
                     /db_xref="CDD:240127"
     misc_feature    complement(order(386193..386195,386310..386312,
                     386319..386321,386388..386390,386469..386471,
                     386481..386483,386508..386510,386523..386528,
                     386535..386537,386553..386555,386643..386645,
                     386751..386753,386775..386777,386781..386783,
                     386787..386789))
                     /gene="hemB"
                     /locus_tag="COSY_0378"
                     /note="active site"
                     /db_xref="CDD:240127"
     misc_feature    complement(order(386640..386642,386751..386753,
                     386775..386777))
                     /gene="hemB"
                     /locus_tag="COSY_0378"
                     /note="aspartate-rich active site metal binding site;
                     other site"
                     /db_xref="CDD:240127"
     misc_feature    complement(order(386388..386390,386553..386555))
                     /gene="hemB"
                     /locus_tag="COSY_0378"
                     /note="Schiff base residues; other site"
                     /db_xref="CDD:240127"
     gene            387191..389059
                     /gene="thiC"
                     /locus_tag="COSY_0379"
                     /db_xref="GeneID:5172391"
     CDS             387191..389059
                     /gene="thiC"
                     /locus_tag="COSY_0379"
                     /note="required for the synthesis of the
                     hydromethylpyrimidine moiety of thiamine"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiC"
                     /protein_id="YP_001219225.1"
                     /db_xref="GI:148244531"
                     /db_xref="GeneID:5172391"
                     /translation="MNQSNSTFKNMSNVNEALIKPFPNSNKIYVQGSRKDIQVPMREI
                     TLTDTIGELAEKNAPIHVYDTSGVYTDSNVNIDLRKGLGNIRVSWIKERNDTEILTEF
                     SSNFSNERRDDVQLNALRFEHLQVPRRAKDTKNVSQMHYAKQGVITPEMEYIAIRENC
                     KWQEYKDQIGQKKGESFDANIPDLITSEFICSEVAKGRAVIPANINHPEVEPMIIGRN
                     FMVKINGNIGNSVLGSSIEEEVSKMIWGIRWGADTIMDLSTGKNIHETREWIIRNSPV
                     PIGTVPIYQALEKVNGIVENLNWEIFRDTLIEQAEQGVDYFTIHAGVRLKHVPLTIDR
                     VTGIVSRGGSIMAKWCLAHHTESFIYTHFEDICEIMKQYDVTFSLGDGLRPGCIADAN
                     DVAQFGELETLGGLVKIAWKHDVQTFIEGPGHVPMQMIKENMDKQLEECGEAPFYTLG
                     PLTTDIAPGYDHITSAIGAAQIGWYGCAMLCYVTPKEHLGLPNKDDVKQGVIAYKIAA
                     HAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARKYHDETMPKQAAKTSH
                     FCSMCGPKFCSMKITQEIKTMNVDEIAKINSIQIEMDKKSAEFLKNNSEIYMKKNT"
     misc_feature    387200..389047
                     /gene="thiC"
                     /locus_tag="COSY_0379"
                     /note="thiamine biosynthesis protein ThiC; Provisional;
                     Region: PRK09284"
                     /db_xref="CDD:236451"
     misc_feature    387248..387481
                     /gene="thiC"
                     /locus_tag="COSY_0379"
                     /note="ThiC-associated domain; Region: ThiC-associated;
                     pfam13667"
                     /db_xref="CDD:222303"
     misc_feature    387599..388942
                     /gene="thiC"
                     /locus_tag="COSY_0379"
                     /note="ThiC family; Region: ThiC; pfam01964"
                     /db_xref="CDD:216813"
     gene            complement(389195..390445)
                     /gene="kdtA"
                     /locus_tag="COSY_0380"
                     /db_xref="GeneID:5172284"
     CDS             complement(389195..390445)
                     /gene="kdtA"
                     /locus_tag="COSY_0380"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-D-manno-octulosonic-acid transferase"
                     /protein_id="YP_001219226.1"
                     /db_xref="GI:148244532"
                     /db_xref="GeneID:5172284"
                     /translation="MDQSLYNIIGYILLPFIILRLIIKGIKTPKFKQRINERLGLITR
                     IQEPIIWVHCVSIGEFKAAIVIIDQLIKQHPNHKLLVTTTTPTGSDAVISYYRDKVVN
                     LYFPYDLPLIIKHYIKQINPKICLILETEIWPNLIHELNKRNIPILLINARLSQQSKE
                     KYQKFTSNLVKQTLNKISLIAAQNQNSANNFIELGARNDYVVITNNIKFDQNTTPDKI
                     ISNALQKIIGKRKTVIFASTHKNEEVQIINEYSKNKYAINALLVIIPRHPERFDVVYK
                     LAKNANLNIARRSENQPARDVQILLGDSMGEMMSYFDIANIVFMGGSLSNTGGHNMLE
                     PAAFAKPIIFGSNTFNFTEISLDLLEQNAAILIQNVSDLFKIIIMLLNDEKQCKVLGY
                     NAQQYLYSKQGAVKNTLQLINKFI"
     misc_feature    complement(389198..390445)
                     /gene="kdtA"
                     /locus_tag="COSY_0380"
                     /note="3-deoxy-D-manno-octulosonic-acid transferase;
                     Reviewed; Region: PRK05749"
                     /db_xref="CDD:235589"
     misc_feature    complement(389810..390355)
                     /gene="kdtA"
                     /locus_tag="COSY_0380"
                     /note="3-Deoxy-D-manno-octulosonic-acid transferase
                     (kdotransferase); Region: Glycos_transf_N; pfam04413"
                     /db_xref="CDD:218074"
     misc_feature    complement(389255..389686)
                     /gene="kdtA"
                     /locus_tag="COSY_0380"
                     /note="Glycosyltransferases catalyze the transfer of sugar
                     moieties from activated donor molecules to specific
                     acceptor molecules, forming glycosidic bonds. The acceptor
                     molecule can be a lipid, a protein, a heterocyclic
                     compound, or another carbohydrate...; Region:
                     Glycosyltransferase_GTB_type; cl10013"
                     /db_xref="CDD:245227"
     gene            390499..391503
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /db_xref="GeneID:5172697"
     CDS             390499..391503
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP1/Obg family GTP-binding protein"
                     /protein_id="YP_001219227.1"
                     /db_xref="GI:148244533"
                     /db_xref="GeneID:5172697"
                     /translation="MKFVDSASVRIEAGKGGAGCLGFRRERYISDGGPDGGDGGDGGH
                     VYFQGQDGLNTLSEFCFKRLFRAKNGQPGSGQNKRGKSAQHLTVEIPLGTKVYDLVTD
                     ELIGEMTKHEQTILVAKGGFHGLGNTRFKSSINRAPRETTPGFPGEVREIGLELSVMA
                     DIGLLGIPNAGKSSLIRQISSARPKIADYPFTTLHPSLSVVSFCDKHIVMADIPGLIE
                     NASKGAGLGFKFLKHLSRAKVLLHVVDILPVDGSDPVKNFLTIEKELKKYDQELANKE
                     KLLVINKIDLLPEKDRNTMVQSLLKDICYKGKVFNISALNGLGCKDLVAGLFKLVLRK
                     "
     misc_feature    390502..391491
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="GTPase CgtA; Reviewed; Region: obgE; PRK12299"
                     /db_xref="CDD:237048"
     misc_feature    390505..390966
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="GTP1/OBG; Region: GTP1_OBG; pfam01018"
                     /db_xref="CDD:110047"
     misc_feature    390976..391491
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="Obg GTPase; Region: Obg; cd01898"
                     /db_xref="CDD:206685"
     misc_feature    390994..391017
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="G1 box; other site"
                     /db_xref="CDD:206685"
     misc_feature    order(391003..391020,391342..391347,391351..391353,
                     391435..391440)
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206685"
     misc_feature    391039..391086
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206685"
     misc_feature    391075..391077
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="G2 box; other site"
                     /db_xref="CDD:206685"
     misc_feature    391132..391143
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="G3 box; other site"
                     /db_xref="CDD:206685"
     misc_feature    order(391141..391164,391171..391209)
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206685"
     misc_feature    391342..391353
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="G4 box; other site"
                     /db_xref="CDD:206685"
     misc_feature    391435..391443
                     /gene="obg"
                     /locus_tag="COSY_0381"
                     /note="G5 box; other site"
                     /db_xref="CDD:206685"
     gene            391500..392270
                     /gene="proB"
                     /locus_tag="COSY_0382"
                     /db_xref="GeneID:5172445"
     CDS             391500..392270
                     /gene="proB"
                     /locus_tag="COSY_0382"
                     /EC_number="2.7.2.11"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="YP_001219228.1"
                     /db_xref="GI:148244534"
                     /db_xref="GeneID:5172445"
                     /translation="MNKQRWVIKIGSSLLTNDGKGLDKTFIATLVKQIKELKQQNIDI
                     ILVSSGAIAEGMKRLGWHGRPENIHKLQAVAAVGQMGLIQTYETLFSQYNIHTAQVLL
                     THVNLANTDQSNNISATLNTLLNFDIVPIVNENDTVATDEIKFGDNDTLAALVANLVN
                     ATQLVILTDQGGVYDADPRQNANAKLIDKIHVNNERLTQVANRAGGSLGSGGMYTKVL
                     AAQIVAKSNVITIIASGRQANVLSKLYEGEPIGTLIYC"
     misc_feature    391500..>392264
                     /gene="proB"
                     /locus_tag="COSY_0382"
                     /note="gamma-glutamyl kinase; Provisional; Region:
                     PRK05429"
                     /db_xref="CDD:235460"
     misc_feature    391512..392261
                     /gene="proB"
                     /locus_tag="COSY_0382"
                     /note="AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes
                     glutamate-dependent ATP cleavage; G5K transfers the
                     terminal phosphoryl group of ATP to the gamma-carboxyl
                     group of glutamate, in the first and controlling step of
                     proline (and, in mammals, ornithine)...; Region:
                     AAK_G5K_ProB; cd04242"
                     /db_xref="CDD:239775"
     misc_feature    order(391536..391538,392001..392009,392016..392021,
                     392127..392129,392133..392135,392145..392147)
                     /gene="proB"
                     /locus_tag="COSY_0382"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239775"
     misc_feature    order(391611..391616,391623..391625,391713..391715,
                     391725..391727,391794..391796,391800..391802,
                     391842..391847,391863..391865,391872..391874,
                     391902..391904,391908..391913)
                     /gene="proB"
                     /locus_tag="COSY_0382"
                     /note="homotetrameric interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239775"
     misc_feature    391647..391670
                     /gene="proB"
                     /locus_tag="COSY_0382"
                     /note="putative phosphate binding site [ion binding];
                     other site"
                     /db_xref="CDD:239775"
     misc_feature    order(391650..391652,391905..391907,391938..391940)
                     /gene="proB"
                     /locus_tag="COSY_0382"
                     /note="putative allosteric binding site; other site"
                     /db_xref="CDD:239775"
     gene            392264..392737
                     /gene="folK"
                     /locus_tag="COSY_0383"
                     /db_xref="GeneID:5172625"
     CDS             392264..392737
                     /gene="folK"
                     /locus_tag="COSY_0383"
                     /EC_number="2.7.6.3"
                     /note="7,8-dihydro-6-hydroxymethylpterin-
                     pyrophosphokinase"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine pyrophosphokinase"
                     /protein_id="YP_001219229.1"
                     /db_xref="GI:148244535"
                     /db_xref="GeneID:5172625"
                     /translation="MLAYIGLGSNLNHPKKQIKNALIALNYTKGIKVGGLSNMYQSKP
                     IDGSKQPDYINAMCQVDTHLTALELLHVCQDIEIKQHRVREKKWSARTIDLDIIIYGV
                     QVIVSTQLIIPHPKMMNRAFVLVPLAELEPNLKVPVLGPIQNLIDNLDTTKLVKL"
     misc_feature    392270..392653
                     /gene="folK"
                     /locus_tag="COSY_0383"
                     /note="7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
                     (HPPK). Folate derivatives are essential cofactors in the
                     biosynthesis of purines, pyrimidines, and amino acids as
                     well as formyl-tRNA. Mammalian cells are able to utilize
                     pre-formed folates after...; Region: HPPK; cd00483"
                     /db_xref="CDD:238269"
     misc_feature    order(392285..392287,392387..392392,392396..392398,
                     392420..392422,392426..392428,392471..392473,
                     392483..392485,392492..392494,392507..392509,
                     392513..392515,392525..392527,392534..392536,
                     392543..392545,392549..392554,392594..392596,
                     392603..392608,392621..392623,392627..392629)
                     /gene="folK"
                     /locus_tag="COSY_0383"
                     /note="catalytic center binding site [active]"
                     /db_xref="CDD:238269"
     misc_feature    order(392471..392473,392483..392485,392492..392494,
                     392507..392509,392513..392515,392534..392536,
                     392549..392554,392594..392596,392603..392608,
                     392621..392623)
                     /gene="folK"
                     /locus_tag="COSY_0383"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238269"
     gene            392734..393516
                     /gene="panB"
                     /locus_tag="COSY_0384"
                     /db_xref="GeneID:5171953"
     CDS             392734..393516
                     /gene="panB"
                     /locus_tag="COSY_0384"
                     /EC_number="2.1.2.11"
                     /note="catalyzes the formation of tetrahydrofolate and
                     2-dehydropantoate from 5,10-methylenetetrahydrofolate and
                     3-methyl-2-oxobutanoate"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="YP_001219230.1"
                     /db_xref="GI:148244536"
                     /db_xref="GeneID:5171953"
                     /translation="MNIEALKVFKESGEKITCLTAYDASFASVFDACGIDIILVGDSL
                     GNVIQGDKNTLDVSMSDMIYHMQAVAKGTQNALRIADMPYQSYTYAEQTLTNAKRLIM
                     AGAQMVKLEGGCEHEASFRILQGNDISVCGHLGLQPQSVVEIDGYRVQGRGKQGANKI
                     IKNALALASWGVKVIVLECVPAELAKQVSQSVSIPIIGIGAGLDCDGQVLVSYDMLGV
                     HVRHVPRFVKNFLTDNGDVKSAVNAFIKAVKDKSFPSKKYSY"
     misc_feature    392740..393495
                     /gene="panB"
                     /locus_tag="COSY_0384"
                     /note="Ketopantoate hydroxymethyltransferase (KPHMT) is
                     the first enzyme in the pantothenate biosynthesis pathway.
                     Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes
                     the first committed step in the biosynthesis of
                     pantothenate (vitamin B5), which is a...; Region:
                     KPHMT-like; cd06557"
                     /db_xref="CDD:119342"
     misc_feature    order(392740..392745,392800..392811,392818..392820,
                     392863..392865,392869..392886,392896..392901,
                     392914..392916,392923..392928,392935..392937,
                     392944..392946,392983..392988,393013..393015,
                     393025..393027,393034..393036,393049..393051,
                     393103..393120,393148..393153,393157..393168,
                     393250..393252,393370..393372,393379..393384,
                     393424..393426,393433..393447)
                     /gene="panB"
                     /locus_tag="COSY_0384"
                     /note="oligomerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:119342"
     misc_feature    order(392791..392793,392848..392850,392854..392862,
                     392974..392976,393058..393060,393130..393132,
                     393145..393147,393265..393267,393358..393360,
                     393364..393366)
                     /gene="panB"
                     /locus_tag="COSY_0384"
                     /note="active site"
                     /db_xref="CDD:119342"
     misc_feature    order(392857..392859,392974..392976,393058..393060)
                     /gene="panB"
                     /locus_tag="COSY_0384"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:119342"
     gene            393516..394364
                     /gene="panC"
                     /locus_tag="COSY_0385"
                     /db_xref="GeneID:5171889"
     CDS             393516..394364
                     /gene="panC"
                     /locus_tag="COSY_0385"
                     /EC_number="6.3.2.1"
                     /note="catalyzes the formation of (R)-pantothenate from
                     pantoate and beta-alanine"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="YP_001219231.1"
                     /db_xref="GI:148244537"
                     /db_xref="GeneID:5171889"
                     /translation="MKLCYQNIQITELVNDWHEQEKTIAFIPTMGGLHQGHLSLIDIA
                     KQKADKVVVSIFVNPAQFDKNEDLDSYPRSLNADLVELEENVDSVFVPDVKQIYPNGI
                     SKYIDVGMIGRILCGKTRPHFFNGMIQVVEILFEIVRPNVAIFGQKDYQQLLVIKQMV
                     KNLSLDICIESGEIIREKSGLAMSTRNQYLSENDAKIAANLYRILTYVKHEVLQNKKI
                     DVLKKMAESDLKQHFKLDYLEVLDANTLKQITDNTCQIIILSAVFLGSVRLIDNIIFL
                     KKDNYV"
     misc_feature    393540..394337
                     /gene="panC"
                     /locus_tag="COSY_0385"
                     /note="pantoate--beta-alanine ligase; Region: panC;
                     TIGR00018"
                     /db_xref="CDD:232784"
     misc_feature    393549..394334
                     /gene="panC"
                     /locus_tag="COSY_0385"
                     /note="Pantoate-beta-alanine ligase; Region: PanC;
                     cd00560"
                     /db_xref="CDD:185673"
     misc_feature    order(393597..393608,393615..393617,393621..393626,
                     393633..393635,393687..393689,393696..393698,
                     393726..393728,393894..393896,393903..393908,
                     393948..393953,393957..393962,393969..393971,
                     394032..394040,394062..394073)
                     /gene="panC"
                     /locus_tag="COSY_0385"
                     /note="active site"
                     /db_xref="CDD:185673"
     misc_feature    order(393597..393605,393615..393617,393624..393626,
                     393633..393635,393696..393698,393903..393908,
                     393948..393953,393957..393962,393969..393971,
                     394035..394040,394059..394064)
                     /gene="panC"
                     /locus_tag="COSY_0385"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:185673"
     misc_feature    order(393597..393599,393603..393605,393687..393689,
                     393696..393698,393903..393908,393915..393917,
                     393969..393971)
                     /gene="panC"
                     /locus_tag="COSY_0385"
                     /note="pantoate-binding site; other site"
                     /db_xref="CDD:185673"
     misc_feature    393615..393626
                     /gene="panC"
                     /locus_tag="COSY_0385"
                     /note="HXXH motif; other site"
                     /db_xref="CDD:185673"
     gene            394357..394935
                     /locus_tag="COSY_0386"
                     /db_xref="GeneID:5171887"
     CDS             394357..394935
                     /locus_tag="COSY_0386"
                     /note="thioredoxin-like proteins and domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219232.1"
                     /db_xref="GI:148244538"
                     /db_xref="GeneID:5171887"
                     /translation="MFNITDKAKVYMADLFAQQDEKDLGLKVDIEKAGTPAATVIFNF
                     CFPKELSKTYQKFEYKGFDVYINKLNFVYLKDSEVALKDSSVGKKLIITAPNAKGEEP
                     KEDAPLEEKIKYVIAADITPGLASHGGFVELVGITKQIDVILNFGGGCQGCSSVKSTL
                     EQGVEAQLKARFPEIKSVRDVTNHANTDNAYM"
     misc_feature    394357..394656
                     /locus_tag="COSY_0386"
                     /note="Iron-sulphur cluster biosynthesis; Region:
                     Fe-S_biosyn; cl00400"
                     /db_xref="CDD:241842"
     misc_feature    394363..394929
                     /locus_tag="COSY_0386"
                     /note="IscR-regulated protein YhgI; Region: YhgI_GntY;
                     TIGR03341"
                     /db_xref="CDD:132384"
     misc_feature    394651..394914
                     /locus_tag="COSY_0386"
                     /note="Thioredoxin-like proteins and domains
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: COG0694"
                     /db_xref="CDD:223766"
     gene            394980..395489
                     /locus_tag="COSY_0387"
                     /db_xref="GeneID:5172437"
     CDS             394980..395489
                     /locus_tag="COSY_0387"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219233.1"
                     /db_xref="GI:148244539"
                     /db_xref="GeneID:5172437"
                     /translation="MITVIDASIKERRDAKAAHELFTINTVIVHLFFTLGLIKLLNID
                     MNSAIYLSILISFVIIIYTYFRTKKAKSNDAYLVYLHWQLSLNRYKLLISAYVFYFLV
                     TSLGLIISTDVPISMDGIRIIDSILSLLGIVPLFFCILLSVVLGSGSMFNAGRSEINQ
                     KLVQKYPKS"
     gene            395489..396418
                     /gene="thiL"
                     /locus_tag="COSY_0388"
                     /db_xref="GeneID:5172157"
     CDS             395489..396418
                     /gene="thiL"
                     /locus_tag="COSY_0388"
                     /EC_number="2.7.4.16"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamin-monophosphate kinase"
                     /protein_id="YP_001219234.1"
                     /db_xref="GI:148244540"
                     /db_xref="GeneID:5172157"
                     /translation="MNEFSLIETYFNWGSSSLANLGIGDDCAVINIDPNYQLVTSVDT
                     LIEGVHFPLNTSASDIAYKSLAVNLSDLAAMGARAKYFTLALTLPNIKKKWLSQFSAS
                     LKSLSDEIGIILVGGDTTKGTLSITINVTGVVEKDKALLRSSAQVGDLIFVSNTISDA
                     AYAWKQLQNNQIPSEYAINHFNRPKPQLVLGQQLSTIANACIDISDGLEQDLKHILTC
                     SNVGASINIDDIPLTNEVKTYIAKTNDWCLVLAGGDDYELCFTVPVKNMNLLKNLQSK
                     NNVTVTQIGIINDSMMLTKIGTFDKQCCSYQHF"
     misc_feature    395489..396415
                     /gene="thiL"
                     /locus_tag="COSY_0388"
                     /note="thiamine monophosphate kinase; Provisional; Region:
                     PRK05731"
                     /db_xref="CDD:235583"
     misc_feature    395492..396349
                     /gene="thiL"
                     /locus_tag="COSY_0388"
                     /note="ThiL (Thiamine-monophosphate kinase) plays a dual
                     role in de novo biosynthesis and in salvage of exogenous
                     thiamine. Thiamine salvage occurs in two steps, with
                     thiamine kinase catalyzing the formation of thiamine
                     phosphate, and ThiL catalyzing the...; Region: ThiL;
                     cd02194"
                     /db_xref="CDD:100030"
     misc_feature    order(395507..395509,395558..395566,395699..395701,
                     395738..395740,395786..395788,395834..395842,
                     395912..395914,396095..396097,396101..396106)
                     /gene="thiL"
                     /locus_tag="COSY_0388"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:100030"
     misc_feature    order(395516..395518,395567..395569,395612..395620,
                     395624..395626,395786..395788,395831..395833,
                     395840..395851,395867..395869,395873..395875)
                     /gene="thiL"
                     /locus_tag="COSY_0388"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100030"
     gene            complement(396455..396865)
                     /gene="dksA"
                     /locus_tag="COSY_0389"
                     /db_xref="GeneID:5172567"
     CDS             complement(396455..396865)
                     /gene="dksA"
                     /locus_tag="COSY_0389"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaK suppressor protein DksA"
                     /protein_id="YP_001219235.1"
                     /db_xref="GI:148244541"
                     /db_xref="GeneID:5172567"
                     /translation="MSQSIYQEILDYQPKKNEKFMNDTQLEHFKNKLNAWREQLVDDA
                     ESTINHIQEDSNQVADINDRATLEEEFALELRTRDRERKLIGKIDKTLHIIELGDYGF
                     CKTCGAEISLMRLEARPTADECIDCKTIAEKKEV"
     misc_feature    complement(396479..396805)
                     /gene="dksA"
                     /locus_tag="COSY_0389"
                     /note="RNA polymerase-binding protein DksA; Region: dksA;
                     TIGR02420"
                     /db_xref="CDD:131473"
     gene            396956..397717
                     /locus_tag="COSY_0390"
                     /db_xref="GeneID:5172245"
     CDS             396956..397717
                     /locus_tag="COSY_0390"
                     /note="CbbY family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="YP_001219236.1"
                     /db_xref="GI:148244542"
                     /db_xref="GeneID:5172245"
                     /translation="MALEALIFDVDGTLANTERDGHLTAFNLAFKELDLDWHWSNKIY
                     HELLNVTGGKLRIKYYLTKYNQTFEHQYLDDFIDSIHQLKTKIYVRLMSQGAVPLRIG
                     VKRLFNEARKANLRLAIATTTTPINVDALITSTLGSESLDWFEVIGSGNIVSKLKPAG
                     DIYTYVLKQMRLDPAKCFAFEDSHNGIISATEAGLKTLITTNEYTKSHCFDGAMVVLN
                     HLGESNVPFQLIKGDKTNATYVSIDYLKELYAKYC"
     misc_feature    396962..397615
                     /locus_tag="COSY_0390"
                     /note="Predicted phosphatase/phosphohexomutase [General
                     function prediction only]; Region: COG0637"
                     /db_xref="CDD:223710"
     misc_feature    397259..397549
                     /locus_tag="COSY_0390"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    397316..397318
                     /locus_tag="COSY_0390"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     gene            397701..398678
                     /locus_tag="COSY_0391"
                     /db_xref="GeneID:5172554"
     CDS             397701..398678
                     /locus_tag="COSY_0391"
                     /note="Similar to the N-terminal region of threonine
                     dehydratase I IlvA Tbd_2363 (505 aa) in Thiobacillus
                     denitrificans ATCC 25259."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine dehydratase"
                     /protein_id="YP_001219237.1"
                     /db_xref="GI:148244543"
                     /db_xref="GeneID:5172554"
                     /translation="MQNIVSRIKRDVVNEVVRKTQLEFASQISMHLDNKIYLKREDLT
                     PVHSFKLRGAYHKIRTLNIRQLSKGVITCSAGNHAQGVAFSAKKLGIYAVIVMPKITP
                     KIKVDSVKSLGAEVILFGNSYDVAYDFSQNIAKKKGYTFIHAFDDLDVIAGQGTIAYE
                     LLEQLDDIDYIFVPVGGGGLITGIASVIKTQRPKIKIIGVEPVGSAAFTRSITSNTHA
                     VLDEVDVFAEGVAVKKVGFENLRIAKKLVNGTVLVSNDEMCAAIKDIYNQNRYIVEPS
                     GALALAGIKRYIFDKQLHNNNIISIVSGANMNFDRLRYITERANLNEYN"
     misc_feature    397728..398672
                     /locus_tag="COSY_0391"
                     /note="Threonine dehydratase [Amino acid transport and
                     metabolism]; Region: IlvA; COG1171"
                     /db_xref="CDD:224092"
     misc_feature    397728..398624
                     /locus_tag="COSY_0391"
                     /note="Threonine dehydratase: The first step in amino acid
                     degradation is the removal of nitrogen. Although the
                     nitrogen atoms of most amino acids are transferred to
                     alpha-ketoglutarate before removal, the alpha-amino group
                     of threonine can be directly...; Region: Thr-dehyd;
                     cd01562"
                     /db_xref="CDD:107205"
     misc_feature    order(397728..397733,397824..397829,398265..398270,
                     398475..398477,398484..398489,398496..398498,
                     398508..398516,398613..398624)
                     /locus_tag="COSY_0391"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107205"
     misc_feature    order(397848..397850,397929..397931,398226..398240,
                     398607..398609)
                     /locus_tag="COSY_0391"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:107205"
     misc_feature    397848..397850
                     /locus_tag="COSY_0391"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:107205"
     gene            399912..401159
                     /gene="icd"
                     /locus_tag="COSY_0392"
                     /db_xref="GeneID:5172064"
     CDS             399912..401159
                     /gene="icd"
                     /locus_tag="COSY_0392"
                     /EC_number="1.1.1.42"
                     /note="Similar to isocitrate dehydrogenase in E14
                     prophage, specific for NADP+."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate dehydrogenase"
                     /protein_id="YP_001219238.1"
                     /db_xref="GI:148244544"
                     /db_xref="GeneID:5172064"
                     /translation="MIYQHIQIPPKGEKISFKKGVIKVPNYPIITYIEGDGIGVDVSP
                     VMKKVIDSIVAKAYNGSKAIQWMNIYAGKKANDIYGEYLPQETLDAIKEFSVSIKGPL
                     TTPVGGGVRSLNVAIRQMLDLFICQRPVKYLKGTPSPVKAPEKVDMVIFRENSEDIYA
                     GIEYQEGTAEVKKVIDFLQYEMGTKKIRFPDTSGIGIKPVSKEGTERLVRAAIQYAID
                     NNKDSVTLVHKGNIMKFTEGSFRNWSYQLACDEFGATTFGDGPWKSFKNPNTGMVIII
                     KDVIADAFLQQILLRPEEYSVIATLNLNGDYISDALAAQVGGIGIAPSANLSDTIAVF
                     EATHGTAPKYAELNKVNPGSIILSAEMMLRHMGWIQAADMVLEAMSNVIQNKTVTYDL
                     ERLMDDATLLSCSEFGDALIDYI"
     misc_feature    399918..401153
                     /gene="icd"
                     /locus_tag="COSY_0392"
                     /note="isocitrate dehydrogenase; Validated; Region:
                     PRK07362"
                     /db_xref="CDD:180944"
     misc_feature    399936..401150
                     /gene="icd"
                     /locus_tag="COSY_0392"
                     /note="isocitrate dehydrogenase; Reviewed; Region:
                     PRK07006"
                     /db_xref="CDD:180792"
     gene            401846..402370
                     /locus_tag="COSY_0393"
                     /db_xref="GeneID:5172581"
     CDS             401846..402370
                     /locus_tag="COSY_0393"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219239.1"
                     /db_xref="GI:148244545"
                     /db_xref="GeneID:5172581"
                     /translation="MKKIIAIATLVAATSASAGFFNNSSNNNGYGYGNGSNNWGPFDG
                     GSNFGPMNGGSNWGPFSGGNNWGPFDGGSNFGPMNGGSNWGPFSNNNDMNNDSDWGFH
                     YNNKNKTKNVSNVTADGKYAGTADAFAKGQADAFAKGQADAFAKAQADAYAKGYADAK
                     ANATVDSRDQVIVK"
     gene            402624..402699
                     /locus_tag="COSY_t16"
                     /db_xref="GeneID:5329734"
     tRNA            402624..402699
                     /locus_tag="COSY_t16"
                     /product="tRNA-Asn"
                     /db_xref="GeneID:5329734"
     gene            403766..405025
                     /locus_tag="COSY_0395"
                     /db_xref="GeneID:5172739"
     CDS             403766..405025
                     /locus_tag="COSY_0395"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219240.1"
                     /db_xref="GI:148244546"
                     /db_xref="GeneID:5172739"
                     /translation="MVHKIECEHCGNKINIEQSIWKSISIDLNSKYVKKDVEMKVREK
                     ALNDEKEKQDEEVAFLVAQERSVLVKKYNDAQKIQEEMIQTEVDKRLILDKELLDKQI
                     REEVKNDLEDAKQKNIENNKIKIENMRLEATVNTMESQHKIDIEIKVAEAINLSEKKA
                     IEDREQQRSENDVKMKQMQKSIEDVHRQSNQGSMQIQGEAQEQTIKSFLKYNFPLDII
                     EPIKQGARGGDCLQHVVNNNNQKCGIIYYESKRTKNFENSWIQKFKADMREKNVDIGV
                     LATQAMPKGMKRAGLVKGIWVCLLEEFKMISHILRKQLIEIYKIRSISENREDIVSHL
                     YRYLTSSEFKMDMEAIVEGFTEMRSDIDSEKKAFNRIWSKRGKQLEKIMLSTVNMYGS
                     LQGISNNSIETINGLELPGADYSQIKK"
     misc_feature    403868..404995
                     /locus_tag="COSY_0395"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4487"
                     /db_xref="CDD:226889"
     misc_feature    404246..405004
                     /locus_tag="COSY_0395"
                     /note="Uncharacterized protein conserved in bacteria
                     (DUF2130); Region: DUF2130; pfam09903"
                     /db_xref="CDD:220464"
     gene            complement(405069..406247)
                     /gene="aspB"
                     /locus_tag="COSY_0396"
                     /db_xref="GeneID:5172566"
     CDS             complement(405069..406247)
                     /gene="aspB"
                     /locus_tag="COSY_0396"
                     /EC_number="2.6.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase"
                     /protein_id="YP_001219241.1"
                     /db_xref="GI:148244547"
                     /db_xref="GeneID:5172566"
                     /translation="MSAYLSDRIQKIKPSATLEVTAKANELKSQGIQIISMGSGEPDF
                     DTPKNIQRAAIQAIKNGQTRYTMVDGTPILKKAIIDKFKRENSLTYTNTEVIVSSGGK
                     QVFYNLCQAVLNKGDEVIITAPFWVSYPDMTLLADATPIIITTGLEQNFKITPKQLES
                     NITNNTKLFVINSPSNPTGVVYSKAELQALANILKKYPKILIITDDIYEHIHWNNNEN
                     FVNIVMVDKTLKDRTIILNGVSKAYAMTGWRIGYGAGPKNIIQAMKKIQGQSTSNPCS
                     ISQAAALEALNGDQSIINIMVRAFKKRHDFIVDALNTINGIECPKSQGAFYAFPRVEG
                     LISRLGLKNDIELSTYCLEILNIALVPGSDFGMPGYIRFSFATNMDNIRKAIDKLSKV
                     "
     misc_feature    complement(405072..406235)
                     /gene="aspB"
                     /locus_tag="COSY_0396"
                     /note="aspartate aminotransferase; Provisional; Region:
                     PRK05764"
                     /db_xref="CDD:235596"
     misc_feature    complement(405075..406145)
                     /gene="aspB"
                     /locus_tag="COSY_0396"
                     /note="Aspartate aminotransferase family. This family
                     belongs to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). Pyridoxal phosphate
                     combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine...; Region: AAT_like;
                     cd00609"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(405501..405503,405525..405530,
                     405534..405536,405624..405626,405720..405722,
                     405870..405872,405942..405950))
                     /gene="aspB"
                     /locus_tag="COSY_0396"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(405405..405407,405414..405416,
                     405501..405509,405645..405647,405840..405842,
                     405939..405941))
                     /gene="aspB"
                     /locus_tag="COSY_0396"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99734"
     misc_feature    complement(405525..405527)
                     /gene="aspB"
                     /locus_tag="COSY_0396"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
     gene            406724..407365
                     /locus_tag="COSY_0397"
                     /db_xref="GeneID:5172274"
     CDS             406724..407365
                     /locus_tag="COSY_0397"
                     /note="radical SAM superfamily protein"
                     /codon_start=1
                     /transl_table=11
                     /product="organic radical activating enzyme"
                     /protein_id="YP_001219242.1"
                     /db_xref="GI:148244548"
                     /db_xref="GeneID:5172274"
                     /translation="MINAKLNINEIFYSIQGEAREVGLPSVFIRLTGCPLKCTYCDTE
                     YAFHGNNLMEIDAIISEIKQYDTTYICVTGGEPLLQKNCYLLLDRLVENNYQVSLETS
                     GSINIQDVNALVSIVMDVKTPSSGESEQNKYTNFKKLTVKDQLKFVIGSHSDFDWSVA
                     ILNQYHTTAGVLFSPVFGNITPTQLADWILDQQLNVRLQLQLHKLLWGDEKGK"
     misc_feature    406739..407362
                     /locus_tag="COSY_0397"
                     /note="putative 7-cyano-7-deazaguanosine (preQ0)
                     biosynthesis protein QueE, gammaproteobacterial type;
                     Region: rSAM_QueE_gams; TIGR04349"
                     /db_xref="CDD:213962"
     misc_feature    406817..>407050
                     /locus_tag="COSY_0397"
                     /note="Radical SAM superfamily. Enzymes of this family
                     generate radicals by combining a 4Fe-4S cluster and
                     S-adenosylmethionine (SAM) in close proximity. They are
                     characterized by a conserved CxxxCxxC motif, which
                     coordinates the conserved iron-sulfur cluster; Region:
                     Radical_SAM; cd01335"
                     /db_xref="CDD:100105"
     misc_feature    order(406823..406825,406829..406831,406835..406837,
                     406841..406849,406940..406942,406946..406951,
                     407021..407029)
                     /locus_tag="COSY_0397"
                     /note="FeS/SAM binding site; other site"
                     /db_xref="CDD:100105"
     gene            complement(407366..407890)
                     /locus_tag="COSY_0398"
                     /db_xref="GeneID:5172486"
     CDS             complement(407366..407890)
                     /locus_tag="COSY_0398"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219243.1"
                     /db_xref="GI:148244549"
                     /db_xref="GeneID:5172486"
                     /translation="MKLIKAILKKIMYKRLLLSILLISSVINANSNNLFNSSLFDNNF
                     IWHDFEQQFRQLNYKINQIQNYSNLRTQSRRYFDNQSNSFIIQIKVNGISKENLSIST
                     NNNTILIKGCVKKVQSNNYNLGTSSGSFFQKFTLPDDVDTNNINASFNNNILSISIPK
                     LKQKKPQVQKISIQ"
     misc_feature    complement(<407465..407647)
                     /locus_tag="COSY_0398"
                     /note="Alpha-crystallin domain (ACD) of
                     alpha-crystallin-type small(s) heat shock proteins (Hsps).
                     sHsps are small stress induced proteins with monomeric
                     masses between 12 -43 kDa, whose common feature is the
                     Alpha-crystallin domain  (ACD). sHsps are generally...;
                     Region: ACD_sHsps-like; cd06464"
                     /db_xref="CDD:107221"
     gene            complement(408137..409234)
                     /gene="aroC"
                     /locus_tag="COSY_0399"
                     /db_xref="GeneID:5172521"
     CDS             complement(408137..409234)
                     /gene="aroC"
                     /locus_tag="COSY_0399"
                     /EC_number="4.2.3.5"
                     /note="catalyzes the formation of chorismate from
                     5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino
                     acid biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="YP_001219244.1"
                     /db_xref="GI:148244550"
                     /db_xref="GeneID:5172521"
                     /translation="MSGNTIGKLFTITTAGESHGEALIGIVDGCPPGLALTEVDLQDD
                     LDLRKPGTSRHTSQRHEEDLVKILSGTFEGKTTGTPIALIIQNTDQRSKDYGNIKDTF
                     RPGHADYTYHQKYGIRDYRGGGRSSARETAMRVACGGIAKKYLKQEYNIKIKGYLSQL
                     GPIKIENSDWLEVHNNPFFCLDANKVKILEKYMDTLRKSGDSVGARINIIVNNMPVGL
                     GEPIFDRLDADIAHSMMSINAVKGVEIGDGFRVVNQKGTEHRDAITLTGFKSNHAGGI
                     FGGISSGQDILVSIALKPTSSLSLPIESIDKRGGPIEVITKGRHDPCVGIRATPIAEA
                     MLAITIMDHVMRHRAQNLNIESITPIIPASI"
     misc_feature    complement(408152..409231)
                     /gene="aroC"
                     /locus_tag="COSY_0399"
                     /note="Chorismate synthase [Amino acid transport and
                     metabolism]; Region: AroC; COG0082"
                     /db_xref="CDD:223160"
     misc_feature    complement(408206..409207)
                     /gene="aroC"
                     /locus_tag="COSY_0399"
                     /note="Chorismase synthase, the enzyme catalyzing the
                     final step of the shikimate pathway; Region:
                     Chorismate_synthase; cd07304"
                     /db_xref="CDD:143612"
     misc_feature    complement(order(408230..408232,408344..408346,
                     408353..408364,408368..408370,408389..408397,
                     408401..408409,408416..408418,408464..408469,
                     408479..408484,408488..408493,408500..408514,
                     408521..408523,408527..408532,408536..408544,
                     408551..408556,408560..408562,408572..408580,
                     408584..408586,408617..408634,408647..408649,
                     408833..408835,408857..408862,408890..408904,
                     408983..408985,408989..408991,408995..408997,
                     409001..409006,409025..409030,409034..409039,
                     409136..409141,409151..409153,409157..409159,
                     409163..409165,409184..409204))
                     /gene="aroC"
                     /locus_tag="COSY_0399"
                     /note="Tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143612"
     misc_feature    complement(order(408251..408253,408263..408265,
                     408344..408352,408356..408361,408518..408523,
                     408839..408841,408848..408859,408917..408922,
                     409091..409093,409178..409180))
                     /gene="aroC"
                     /locus_tag="COSY_0399"
                     /note="active site"
                     /db_xref="CDD:143612"
     misc_feature    complement(order(408254..408256,408263..408265,
                     408272..408274,408344..408352,408356..408358,
                     408518..408526,408854..408856,408860..408862,
                     408914..408922))
                     /gene="aroC"
                     /locus_tag="COSY_0399"
                     /note="FMN-binding site [chemical binding]; other site"
                     /db_xref="CDD:143612"
     gene            complement(409726..409802)
                     /locus_tag="COSY_t17"
                     /db_xref="GeneID:5329750"
     tRNA            complement(409726..409802)
                     /locus_tag="COSY_t17"
                     /product="tRNA-Arg"
                     /db_xref="GeneID:5329750"
     gene            410000..410695
                     /gene="pyrF"
                     /locus_tag="COSY_0401"
                     /db_xref="GeneID:5172190"
     CDS             410000..410695
                     /gene="pyrF"
                     /locus_tag="COSY_0401"
                     /EC_number="4.1.1.23"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="YP_001219245.1"
                     /db_xref="GI:148244551"
                     /db_xref="GeneID:5172190"
                     /translation="MKNIKVENRLIFALDVSEIKQAKDLVIQLDNSINFYKIGMELLM
                     TGQYFNLLDWLLEKDKQVFVDLKFFDVPETVGRTIKRLSQYGATFVTIHGNQALMEKA
                     NENKYNLKILAVTALTSIDRGDLDDLGFNCDVLELVVSRAKRAFEAGCDGVVSSGLEV
                     PFLRKYVDSKLIVVTPGIRPVVNDDDQKRIVDVVTAFNSGSDYIVVGRPIKNATSPYQ
                     AATDIQTIIKGCF"
     misc_feature    410027..410668
                     /gene="pyrF"
                     /locus_tag="COSY_0401"
                     /note="Orotidine 5&apos;-phosphate decarboxylase (ODCase)
                     is a dimeric enzyme that decarboxylates orotidine
                     5&apos;-monophosphate (OMP) to form uridine
                     5&apos;-phosphate (UMP), an essential step in the
                     pyrimidine biosynthetic pathway. In mammals, UMP
                     synthase...; Region: OMP_decarboxylase_like; cd04725"
                     /db_xref="CDD:240076"
     misc_feature    order(410036..410038,410042..410044,410108..410110,
                     410114..410116,410192..410194,410198..410200,
                     410348..410353,410525..410527,410618..410623)
                     /gene="pyrF"
                     /locus_tag="COSY_0401"
                     /note="active site"
                     /db_xref="CDD:240076"
     misc_feature    order(410114..410116,410120..410125,410195..410200,
                     410204..410209,410216..410221,410228..410233,
                     410276..410284,410297..410299,410348..410350,
                     410408..410410,410621..410623)
                     /gene="pyrF"
                     /locus_tag="COSY_0401"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:240076"
     gene            410715..410791
                     /locus_tag="COSY_t18"
                     /db_xref="GeneID:5329765"
     tRNA            410715..410791
                     /locus_tag="COSY_t18"
                     /product="tRNA-Val"
                     /db_xref="GeneID:5329765"
     gene            411117..412310
                     /locus_tag="COSY_0403"
                     /db_xref="GeneID:5172411"
     CDS             411117..412310
                     /locus_tag="COSY_0403"
                     /note="Similar to 2-polyprenyl-6-methoxyphenol hydroxylase
                     in ubiquinone biosynthesis, UbiH/UbiF/VisC/COQ6."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219246.1"
                     /db_xref="GI:148244552"
                     /db_xref="GeneID:5172411"
                     /translation="MKVDIVIIGGGPSGLSFASAMLNSNIKILLIERSSLDSIASPQV
                     DGREIALTHLSLKILKKFGVWDLINQAEVSPLKEAKVFDGDSPSLLNFTTENTSIEAL
                     GYLVPNYQIRKALYTKVKQEKKINIITNMVVEDVIQLDDCSQVILSNGDKVETKLVIA
                     ADSRFSDIRRKVGIPTLIKDFSKLMIVTQMSHELSHNNVALERFDYGRTLALLPMVGN
                     VSSIVLTVKTNQSQAILKMNETDFNQMITQSFKDELGKMMQIGERYSYPLIATHAQTF
                     ISKRFALIGDASVGMHPVTAHGFNLGLRGQAILAKLVNEALDNGQDIGSKSLLKLYEK
                     KHINLTRLMFFSTNSIVALFTNDAPVIKQIRRFVLKFAEHFPPIKYLIFHHLTQDKKY
                     KSFYF"
     misc_feature    411117..412289
                     /locus_tag="COSY_0403"
                     /note="hypothetical protein; Provisional; Region:
                     PRK09126"
                     /db_xref="CDD:236385"
     misc_feature    411120..412253
                     /locus_tag="COSY_0403"
                     /note="ubiquinone biosynthesis hydroxylase family protein;
                     Provisional; Region: PRK07608; cl17314"
                     /db_xref="CDD:247868"
     gene            412310..412948
                     /gene="pdxH"
                     /locus_tag="COSY_0404"
                     /db_xref="GeneID:5172702"
     CDS             412310..412948
                     /gene="pdxH"
                     /locus_tag="COSY_0404"
                     /EC_number="1.4.3.5"
                     /note="pyridoxamine 5'-phosphate oxidase"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine-phosphate oxidase"
                     /protein_id="YP_001219247.1"
                     /db_xref="GI:148244553"
                     /db_xref="GeneID:5172702"
                     /translation="MKVDLTGLRREFTQSGLNRTDLDNSPFGQFNLWFEQAQKADIIE
                     PSAMSLATSDNNEIGIRTVLLKYFDMYGFVFFTNYNSKKSKELQSNPNVALLFPWLVL
                     ERQVKISGYVEKISMLESLKYFSSRPKASQLGSWASQQSSSLSSRKVLLSQFELMKVK
                     FSNGKVPLPDFWGGYRVVPLKIEFWQGRENRLHDRFIYQLNKGKWRIERLAP"
     misc_feature    412382..412945
                     /gene="pdxH"
                     /locus_tag="COSY_0404"
                     /note="pyridoxamine-phosphate oxidase; Region: pdxH;
                     TIGR00558"
                     /db_xref="CDD:211586"
     misc_feature    412409..412657
                     /gene="pdxH"
                     /locus_tag="COSY_0404"
                     /note="Pyridoxamine 5&apos;-phosphate oxidase; Region:
                     Pyridox_oxidase; pfam01243"
                     /db_xref="CDD:216385"
     misc_feature    412823..412945
                     /gene="pdxH"
                     /locus_tag="COSY_0404"
                     /note="Pyridoxine 5&apos;-phosphate oxidase C-terminal
                     dimerisation region; Region: PNPOx_C; pfam10590"
                     /db_xref="CDD:204522"
     gene            complement(412937..413740)
                     /gene="aroE"
                     /locus_tag="COSY_0405"
                     /db_xref="GeneID:5171868"
     CDS             complement(412937..413740)
                     /gene="aroE"
                     /locus_tag="COSY_0405"
                     /EC_number="1.1.1.25"
                     /note="AroE; catalyzes the conversion of shikimate to
                     3-dehydroshikimate"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate 5-dehydrogenase"
                     /protein_id="YP_001219248.1"
                     /db_xref="GI:148244554"
                     /db_xref="GeneID:5171868"
                     /translation="MYKFAVFGNPINHSLSPNIQNQFAKQTGFEISYDKILAPVDDFV
                     SSVQAFINQGANGFNITVPFKLDAFKFANELTLNAKIAGSVNTIKIEADKIIGENTDG
                     IGLIKDLTHNIGIKLKNKVILILGAGGATQGILFPILKQKPNQVIISNRTHSKAIRLA
                     KNFSKFGNTCSFSLNKIKYKSVDIIINATSASFDGRIPNIAFSIANNAVCYDLMYGYQ
                     TPFMSWAKTNHAKMISDGLGMLVEQAAIAFEFWTGAKPDTKKVLSNLRR"
     misc_feature    complement(412940..413740)
                     /gene="aroE"
                     /locus_tag="COSY_0405"
                     /note="shikimate 5-dehydrogenase; Reviewed; Region: aroE;
                     PRK00258"
                     /db_xref="CDD:234703"
     misc_feature    complement(413477..413725)
                     /gene="aroE"
                     /locus_tag="COSY_0405"
                     /note="Shikimate dehydrogenase substrate binding domain;
                     Region: Shikimate_dh_N; pfam08501"
                     /db_xref="CDD:149523"
     misc_feature    complement(412982..413443)
                     /gene="aroE"
                     /locus_tag="COSY_0405"
                     /note="NAD(P) binding domain of Shikimate dehydrogenase;
                     Region: NAD_bind_Shikimate_DH; cd01065"
                     /db_xref="CDD:133443"
     misc_feature    complement(order(413012..413014,413021..413023,
                     413096..413098,413438..413440))
                     /gene="aroE"
                     /locus_tag="COSY_0405"
                     /note="shikimate binding site; other site"
                     /db_xref="CDD:133443"
     misc_feature    complement(order(413021..413026,413033..413035,
                     413102..413104,413171..413179,413288..413293,
                     413351..413353,413360..413362))
                     /gene="aroE"
                     /locus_tag="COSY_0405"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:133443"
     gene            complement(413763..415484)
                     /locus_tag="COSY_0406"
                     /db_xref="GeneID:5172206"
     CDS             complement(413763..415484)
                     /locus_tag="COSY_0406"
                     /note="Similar to the N-terminal region of ribonuclease E
                     Rne (1029 aa) in Marinomonas sp. MED121."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219249.1"
                     /db_xref="GI:148244555"
                     /db_xref="GeneID:5172206"
                     /translation="MNHILINATHSEEIRVGIIKNKKLTGLNIETSLNKKTKGNIYRG
                     KISRIEQSLEAAFVDYGKEKQGFLPFKEIAETLYNNTKTEGEKLTISDVLKEGQKIIV
                     QIEKEERGNKGAALSTYINLAGAYMILMPNNPKSHGISRQIVSSDRQSLKEIINRIIL
                     PKHSGLIIRTAGSGKSFEELQWEVDYLTDLWKSINTMALAHGAPFLIYQESDIIIRTL
                     RDHLRSDTDSVIIDELEAFQNAKEFVSFVLPHYLDRIKFFDVSEHSLFSHMGIETQVK
                     SVFNREVSLRTGATIVFDPTEALTSIDINSARATKGADIKETAYNTNLEAAKEIAIQL
                     QLRDIGGLIVIDFIDMASEEHRVSIEKAMEKAISLDRARIQIGTISQFGLLEMSRQRL
                     MNSVTESVEKPCTICHGRGTTPTIPTLALTILRQLENSCNAAKQTARLTIQSSIEVIT
                     YILNEKRQEVIKLEDKHSIKITLLPNPYMQFPNFTINKQKWGKKSQHKSYQGISKPQH
                     ILVENGLANQAEIPAINVNRPNTRVPEKKIFLFEKIKNTLFGKKKKQPNKRRTNPNNR
                     NRNKNRK"
     misc_feature    complement(414021..415484)
                     /locus_tag="COSY_0406"
                     /note="Ribonucleases G and E [Translation, ribosomal
                     structure and biogenesis]; Region: CafA; COG1530"
                     /db_xref="CDD:224447"
     misc_feature    complement(415113..415385)
                     /locus_tag="COSY_0406"
                     /note="S1_RNase_E: RNase E and RNase G, S1-like
                     RNA-binding domain. RNase E is an essential
                     endoribonuclease in the processing and degradation of RNA.
                     In addition to its role in mRNA degradation, RNase E has
                     also been implicated in the processing of rRNA, and...;
                     Region: S1_RNase_E; cd04453"
                     /db_xref="CDD:239900"
     misc_feature    complement(order(415188..415190,415200..415202,
                     415356..415358))
                     /locus_tag="COSY_0406"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239900"
     misc_feature    complement(order(415116..415118,415146..415151,
                     415158..415160,415167..415169,415284..415286))
                     /locus_tag="COSY_0406"
                     /note="oligonucleotide binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239900"
     gene            complement(415824..416543)
                     /locus_tag="COSY_0407"
                     /db_xref="GeneID:5172656"
     CDS             complement(415824..416543)
                     /locus_tag="COSY_0407"
                     /note="short chain dehydrogenase/reductase family"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_001219250.1"
                     /db_xref="GI:148244556"
                     /db_xref="GeneID:5172656"
                     /translation="MKIALITGGAYRIGMQICHTLHRDGYFVIIHYRNSFQAANNLMN
                     KLNNIRQNSASILQAELSNIQEVNKLCNAIKSLEILVNNASIFYSTPVDKLNQHDYQS
                     IMNTNLMAPLFLSSTLSDKLAHNQGCIINIIDIHSERPLKNYTIYSISKAAVAMMTKT
                     LAKELAPNVRVCGVSPGSILWPTNVAKLNQVQKNKILKKIVLRKQGSAQDIADTVLFL
                     AKSTYITGQIINVDGGRTLNQ"
     misc_feature    complement(415830..416540)
                     /locus_tag="COSY_0407"
                     /note="pteridine reductase; Provisional; Region: PRK09135"
                     /db_xref="CDD:181668"
     misc_feature    complement(415842..416540)
                     /locus_tag="COSY_0407"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    complement(order(416007..416018,416091..416093,
                     416103..416105,416142..416150,416289..416297,
                     416442..416450,416505..416507,416511..416516,
                     416520..416522))
                     /locus_tag="COSY_0407"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    complement(order(416091..416093,416103..416105,
                     416142..416144,416223..416225))
                     /locus_tag="COSY_0407"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            416531..417652
                     /locus_tag="COSY_0408"
                     /db_xref="GeneID:5172520"
     CDS             416531..417652
                     /locus_tag="COSY_0408"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219251.1"
                     /db_xref="GI:148244557"
                     /db_xref="GeneID:5172520"
                     /translation="MLFSYKIRQVILEQIIKNTIIQNAGPIGFDEFMNLALYYPALGY
                     YRSGLEKFSKNGDFITAPETSDLFGFCLANQCAQVLNGTNDILEFGSGSGILATQILF
                     ELGRLKKLPQKYYILELSGELKHRQAETISKVLPELIDRIVWLDELPSDFSGVVIANE
                     VLDAMPAKRVIYKNKQFYELGIDHHENEFFWRKFDSPYQNDKILLPNNVIEDYRTEIN
                     LHAIAWIDSLYNATNKALVLLIDYGMSRDEYFHPQRLDGTLRCYYHHKASENPFLNIG
                     KQDITTSVNFSDIADQASISGFKVNGYATQALFLISLGISDYLLKQKDKNKRMNLAQQ
                     IKQLVLPSVMGESFKVLALSKKLSVRLIGFVEQDLSGKL"
     misc_feature    416531..417601
                     /locus_tag="COSY_0408"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG1565"
                     /db_xref="CDD:224481"
     gene            417670..418464
                     /gene="bacA"
                     /locus_tag="COSY_0409"
                     /db_xref="GeneID:5172373"
     CDS             417670..418464
                     /gene="bacA"
                     /locus_tag="COSY_0409"
                     /EC_number="3.6.1.27"
                     /note="BacA; phosphatase activity in Escherichia coli not
                     kinase; involved in bacitracin resistance as bacitracin
                     supposedly sequesters undecaprenyl disphosphate which
                     reduces the pool of lipid carrier available to the cell"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl pyrophosphate phosphatase"
                     /protein_id="YP_001219252.1"
                     /db_xref="GI:148244558"
                     /db_xref="GeneID:5172373"
                     /translation="MDVSQTIVLALIQGLSEFLPISSSAHLILVPKLTNWTDQGLIFD
                     VVVHMGTLSAVIFYYQAMIRSLFFDFYYSIIKRQIIGQSKLAWGVLLGTIPIGLVGMI
                     FKDFVAVDLRSIEIIAYTTLVFGLLLGFASWFNHKNKNPKSTISWIDVSFVSMMQILA
                     LIPGTSRSGITITACMLVGLSRKLSIQFSFLLSIPVITLSLILMLIDLYHQTQLVNVS
                     LLVLGFVISTISAYATIIFVIRLIDMVGMTPFVIYRLILGVFLFFL"
     misc_feature    417670..418461
                     /gene="bacA"
                     /locus_tag="COSY_0409"
                     /note="undecaprenyl pyrophosphate phosphatase; Reviewed;
                     Region: PRK00281"
                     /db_xref="CDD:234712"
     gene            420095..421006
                     /gene="lpxC"
                     /locus_tag="COSY_0410"
                     /db_xref="GeneID:5172388"
     CDS             420095..421006
                     /gene="lpxC"
                     /locus_tag="COSY_0410"
                     /EC_number="3.5.1.-"
                     /note="zinc-dependent; catalyzes the deacetylation of
                     UDP-(3-O-acyl)-N-acetylglucosamine to
                     UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second
                     step of lipid A biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     deacetylase"
                     /protein_id="YP_001219253.1"
                     /db_xref="GI:148244559"
                     /db_xref="GeneID:5172388"
                     /translation="MIKQRTIKKEVKARGIGIHSGSVVNMTLIPAKEDHGVVFRRMDV
                     GDKLVRAHSAFVNEVVLSTGLENKGVKVSTVEHLMSAFSALGIDNVLVELDSFEVPIM
                     DGSSAPFIFLVQSAGIEEQSTHKKFFVIKDTIRVENGDSWAQVSKYEGFKVSLEIDFD
                     HKKVKESGEKLSINFSKQSYLKEISRARTFGYMKDVEMMQRQNLALGASMDNAIALSD
                     DDVLNEDGMRYQNEFVKHKILDIVGDLYLLGSNLIGHYEGYKTGHLLNDQLLSTILAK
                     PDTWSIETFEEDNSPIQFYSEDWQNSL"
     misc_feature    420095..420976
                     /gene="lpxC"
                     /locus_tag="COSY_0410"
                     /note="UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     deacetylase; Reviewed; Region: lpxC; PRK13186"
                     /db_xref="CDD:237294"
     misc_feature    420098..420922
                     /gene="lpxC"
                     /locus_tag="COSY_0410"
                     /note="UDP-3-O-acyl N-acetylglycosamine deacetylase;
                     Region: LpxC; pfam03331"
                     /db_xref="CDD:202596"
     gene            421071..422804
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /db_xref="GeneID:5172265"
     CDS             421071..422804
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /EC_number="2.2.1.6"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="YP_001219254.1"
                     /db_xref="GI:148244560"
                     /db_xref="GeneID:5172265"
                     /translation="MKLNGAQILVNSLKSEGVKHIFGYPGGAVLHIYDALNACDEIEH
                     ILVRHEQGAAHAADGYTRASGKCGVTLVTSGPGITNAVTGIATAYMDSIPMVIISGQV
                     PSALIGNDAFQEVDAVGITRSCVKHNFLIKNINQIVNTIKKAFHIATTGRPGPVLIDI
                     PKDITIATVEPKPYPNSVEMRSYQVPSRADSAKINAAADLISLAKCPIVYSGGGCIIG
                     NADQELRAFTRQLGFPITQTLMGLGAYPATDKQSLGMLGMHGTYEANMAMHDADCVIA
                     AGVRFDDRVTANIDKFCPNAKIIHIDIDPSSISKNVAVDIAIVGDVKLVLSDLIVKMK
                     TKFIQDISLWWLQIDRWRSVNSLAYQTKLGIIKPQTVIETLYEVTKGNAIVTSDVGQH
                     QMWAAQYYQFDYPRRWINSGGLGTMGFGLPAAMGAKLAKPELNVACVTGEGSIQMMTQ
                     ELSTMLQYATPVKIINLNNGYLGMVRQWQEFFYEKRYSMSYMDALPNFVKLAESYGHI
                     GIKVEKEQDLKPALIEAFKQKDRTVFLDILTDPTENVFPMIPSGAGHHEMLLAGRDEM
                     ASMNDDGLNLV"
     misc_feature    421077..422762
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /note="acetolactate synthase 3 catalytic subunit;
                     Validated; Region: PRK06965"
                     /db_xref="CDD:180780"
     misc_feature    421089..421556
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /note="Pyrimidine (PYR) binding domain of POX and related
                     proteins; Region: TPP_PYR_POX_like; cd07035"
                     /db_xref="CDD:132918"
     misc_feature    order(421128..421130,421143..421148,421158..421160,
                     421170..421172,421197..421217,421224..421226,
                     421233..421238,421245..421250,421254..421262,
                     421296..421298,421317..421319,421329..421331,
                     421338..421343)
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    order(421143..421151,421158..421160,421170..421172,
                     421200..421202,421206..421217,421221..421223,
                     421296..421298,421305..421310,421314..421319,
                     421326..421328,421428..421430,421437..421439)
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    order(421143..421145,421218..421220,421296..421298,
                     421308..421310)
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    421650..422057
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /note="Thiamine pyrophosphate enzyme, central domain;
                     Region: TPP_enzyme_M; pfam00205"
                     /db_xref="CDD:215786"
     misc_feature    422166..422726
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /note="Thiamine pyrophosphate (TPP) family,
                     Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding
                     module; composed of proteins similar to the large
                     catalytic subunit of AHAS. AHAS catalyzes the condensation
                     of two molecules of pyruvate to give the...; Region:
                     TPP_AHAS; cd02015"
                     /db_xref="CDD:238973"
     misc_feature    order(422235..422246,422313..422315,422319..422321,
                     422394..422402,422409..422411,422475..422477)
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238973"
     misc_feature    order(422304..422306,422313..422315,422319..422321,
                     422406..422411,422415..422420,422439..422441,
                     422556..422561,422571..422573,422580..422582)
                     /gene="ilvI"
                     /locus_tag="COSY_0411"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238973"
     gene            422801..423298
                     /gene="ilvH"
                     /locus_tag="COSY_0412"
                     /db_xref="GeneID:5172733"
     CDS             422801..423298
                     /gene="ilvH"
                     /locus_tag="COSY_0412"
                     /EC_number="2.2.1.6"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="YP_001219255.1"
                     /db_xref="GI:148244561"
                     /db_xref="GeneID:5172733"
                     /translation="MRHIISILLENEAGALSRVAGLFSARGFNIESLTVVATNDSTLS
                     RMTIVSIADDGIIEKIVKQLNKLIDVIKVTDLTATEHIERELLLVKVNVNQQTQVNID
                     KQIDAFSCKLVDVSEDIYTIELAGKSKKINDFLANLDASKILDVSRTGVTGICMKNRN
                     LTKGA"
     misc_feature    422801..423283
                     /gene="ilvH"
                     /locus_tag="COSY_0412"
                     /note="acetolactate synthase 3 regulatory subunit;
                     Reviewed; Region: ilvH; PRK11895"
                     /db_xref="CDD:183365"
     misc_feature    422807..423022
                     /gene="ilvH"
                     /locus_tag="COSY_0412"
                     /note="N-terminal ACT domain of the Escherichia coli
                     IlvH-like regulatory subunit of acetohydroxyacid synthase
                     (AHAS); Region: ACT_AHAS; cd04878"
                     /db_xref="CDD:153150"
     misc_feature    order(422825..422827,422831..422833,422846..422848,
                     422885..422890,422903..422905,422930..422932)
                     /gene="ilvH"
                     /locus_tag="COSY_0412"
                     /note="putative valine binding site [chemical binding];
                     other site"
                     /db_xref="CDD:153150"
     misc_feature    order(422837..422842,422849..422851,422870..422872,
                     422879..422881,422891..422905,422933..422935)
                     /gene="ilvH"
                     /locus_tag="COSY_0412"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:153150"
     misc_feature    423047..423262
                     /gene="ilvH"
                     /locus_tag="COSY_0412"
                     /note="Small subunit of acetolactate synthase; Region:
                     ALS_ss_C; pfam10369"
                     /db_xref="CDD:204463"
     gene            423322..424326
                     /gene="ilvC"
                     /locus_tag="COSY_0413"
                     /db_xref="GeneID:5172685"
     CDS             423322..424326
                     /gene="ilvC"
                     /locus_tag="COSY_0413"
                     /EC_number="1.1.1.86"
                     /note="catalyzes the formation of
                     (R)-2,3-dihydroxy-3-methylbutanoate from
                     (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and
                     isoleucine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="YP_001219256.1"
                     /db_xref="GI:148244562"
                     /db_xref="GeneID:5172685"
                     /translation="MNIYYDKNADLNIIKDMKVAIVGYGSQGHAHANNLRDSNVEVVV
                     ALRDGSASSKKASDAGLNVKSIKQATAWADLIMVLAPDEFQAQIYTDSIEPNLKQGAT
                     LAFAHGFNIHYNRIIPRADLDVIMIAPKAPGHTVRSEFVKGGGIPDLIAVFQDVSGNA
                     KDTALSYASAIGGGRTGILETSFKDETETDLFGEQVVLCGGTTALVQAGFETLVEAGY
                     EPEMAYFECLHELKLIVDLMYEGGIANMRYSISNTAEYGDITRGSRIVTADTKDEMKK
                     ILIEIQNGVFAKEFVANVGELPAHREVQRAHQIEQVGESLRSMMPWINKNKIVDQSKN
                     "
     misc_feature    423322..424296
                     /gene="ilvC"
                     /locus_tag="COSY_0413"
                     /note="ketol-acid reductoisomerase; Provisional; Region:
                     PRK05479"
                     /db_xref="CDD:235491"
     misc_feature    423358..423852
                     /gene="ilvC"
                     /locus_tag="COSY_0413"
                     /note="Acetohydroxy acid isomeroreductase, catalytic
                     domain; Region: IlvN; pfam07991"
                     /db_xref="CDD:116601"
     misc_feature    423868..424293
                     /gene="ilvC"
                     /locus_tag="COSY_0413"
                     /note="Acetohydroxy acid isomeroreductase, catalytic
                     domain; Region: IlvC; pfam01450"
                     /db_xref="CDD:216510"
     gene            424377..425123
                     /gene="pssA"
                     /locus_tag="COSY_0414"
                     /db_xref="GeneID:5172724"
     CDS             424377..425123
                     /gene="pssA"
                     /locus_tag="COSY_0414"
                     /EC_number="2.7.8.8"
                     /note="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine synthase"
                     /protein_id="YP_001219257.1"
                     /db_xref="GI:148244563"
                     /db_xref="GeneID:5172724"
                     /translation="MERKTKRGIYLLPNILTTFGLFSGFFAIILATKSQYSDAAIAIF
                     IAMLWDGLDGRVARLTNSQSEFGAQYDSMADMISFGVAPALLMYFWLLSDLGKIGWLG
                     AFVYVAAGALRLARFNTQIGIEDKCYFQGLPSPAAAALIAGLVWTKEMIGVTGYDQNL
                     ILASWIILVGSGVLMVSNIRYNSFKEINLKGRSSFKLLLFATLIIIVIILEPSAILFV
                     FFFIYALSGLLTTMVEVRKKRRLKKHHLKG"
     misc_feature    424395..425063
                     /gene="pssA"
                     /locus_tag="COSY_0414"
                     /note="Phosphatidylserine synthase [Lipid metabolism];
                     Region: PssA; COG1183"
                     /db_xref="CDD:224104"
     misc_feature    424401..424679
                     /gene="pssA"
                     /locus_tag="COSY_0414"
                     /note="CDP-alcohol phosphatidyltransferase; Region:
                     CDP-OH_P_transf; pfam01066"
                     /db_xref="CDD:216278"
     gene            425300..426835
                     /gene="leuA"
                     /locus_tag="COSY_0415"
                     /db_xref="GeneID:5172028"
     CDS             425300..426835
                     /gene="leuA"
                     /locus_tag="COSY_0415"
                     /EC_number="2.3.3.13"
                     /note="catalyzes the formation of 2-isopropylmalate from
                     acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="YP_001219258.1"
                     /db_xref="GI:148244564"
                     /db_xref="GeneID:5172028"
                     /translation="MTNKLIIFDTTLRDGEQSPGASMTKDEKIRIAKVLEKMKVDVIE
                     AGFAIASEGDFEAVQAVANIVQNSVICSLARALDKDIDRAGEALKGANASRIHTFIAT
                     SNIHMKMKLQMTPDQVVGQAVRAVKRANRYTDNIEFSPEDAGRSDEDFLCYIIEAVIK
                     AGATTINIPDTVGYNIPHQFGATIKSLIERIPNSDKAIFSAHCHNDLGLAVANSLSAV
                     LNGARQVECTINGLGERAGNTSLEELVMAVRTRQDIFDCDTNIDTMHILSASRLASSV
                     TGFIIQPNKAIVGANAFAHEAGIHQDGVLKHRETYEIMRAEDVGWNANQLVLGKHSGR
                     NAFKVRLAKLGVEFNDDGSLNDAFRRFKELADKKHEIFDEDLQALVSETQTESCDEAI
                     KLVSLKVCTETNEKNTATVVLFINDKKKTATANTSGAVDATFSAINSLASIKINLQLY
                     SVSNVTQGTDALGEVNVRLEYNGRIVNGQGVDTDIITASAKAYVHGLNKVLTVTNKAH
                     PQI"
     misc_feature    425300..426829
                     /gene="leuA"
                     /locus_tag="COSY_0415"
                     /note="2-isopropylmalate synthase; Validated; Region:
                     PRK00915"
                     /db_xref="CDD:234864"
     misc_feature    425318..426121
                     /gene="leuA"
                     /locus_tag="COSY_0415"
                     /note="2-isopropylmalate synthase (IPMS), N-terminal
                     catalytic TIM barrel domain; Region: DRE_TIM_IPMS;
                     cd07940"
                     /db_xref="CDD:163678"
     misc_feature    order(425336..425341,425348..425350,425429..425431,
                     425522..425524,425588..425590,425714..425716,
                     425720..425722,425804..425806,425810..425812,
                     425903..425905,425909..425911)
                     /gene="leuA"
                     /locus_tag="COSY_0415"
                     /note="active site"
                     /db_xref="CDD:163678"
     misc_feature    order(425336..425341,425429..425431)
                     /gene="leuA"
                     /locus_tag="COSY_0415"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:163678"
     misc_feature    order(425903..425905,425909..425911)
                     /gene="leuA"
                     /locus_tag="COSY_0415"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163678"
     misc_feature    426407..426796
                     /gene="leuA"
                     /locus_tag="COSY_0415"
                     /note="LeuA allosteric (dimerisation) domain; Region:
                     LeuA_dimer; smart00917"
                     /db_xref="CDD:214910"
     gene            426832..427251
                     /locus_tag="COSY_0416"
                     /db_xref="GeneID:5172299"
     CDS             426832..427251
                     /locus_tag="COSY_0416"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219259.1"
                     /db_xref="GI:148244565"
                     /db_xref="GeneID:5172299"
                     /translation="MNESLRSRYLEVFAIPEFLHIQAKNQDLNVLKIDIKCLVIETKN
                     PSSFCQTGKTQDFLFKMLGAIGLKKSDIKYISININDLDQTLNKYNAKTVLLMDVGLK
                     PSSIQHFYIHHPSNILTNDKLKRETWETLKKVKQCLK"
     misc_feature    <427147..427245
                     /locus_tag="COSY_0416"
                     /note="Uracil-DNA glycosylases (UDG) and related enzymes;
                     Region: UDG_like; cl00483"
                     /db_xref="CDD:241896"
     gene            427239..427931
                     /locus_tag="COSY_0417"
                     /db_xref="GeneID:5172305"
     CDS             427239..427931
                     /locus_tag="COSY_0417"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219260.1"
                     /db_xref="GI:148244566"
                     /db_xref="GeneID:5172305"
                     /translation="MSQVDYSLLGYRRPKLTTPNGETKLLMHSCCAPCSGEIMEALAV
                     SNIDTTIFFYNPNIHPKKEYELRKEENMRFAQKLNMLFIDADYDYNTWFDRTRGQEYE
                     PERGKRCTTCFDMRFEVTVQYAQNHGFNLISSTLGISRWKDINQINNCGIRATQLFKN
                     IYYWDFNWRKQGGSSRMLELSKRETFYQQEYCGCVYSLRDTNRWRVSCGREKVERGVK
                     FYQQTIESSKDV"
     misc_feature    427296..427907
                     /locus_tag="COSY_0417"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG1636"
                     /db_xref="CDD:224551"
     gene            complement(427928..428827)
                     /gene="argF"
                     /locus_tag="COSY_0418"
                     /db_xref="GeneID:5172406"
     CDS             complement(427928..428827)
                     /gene="argF"
                     /locus_tag="COSY_0418"
                     /EC_number="2.1.3.3"
                     /note="catalyzes the formation of L-citrulline from
                     carbamoyl phosphate and L-ornithine in arginine
                     biosynthesis and degradation"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="YP_001219261.1"
                     /db_xref="GI:148244567"
                     /db_xref="GeneID:5172406"
                     /translation="MIKHFINLNDLSNYDLTQIIKQAIKLKEQYKSGKINKALENKTL
                     AMIFDKSSTRTRVSFEAGMTQLGGRALFLSDKDIQLGRGEPIIDSAIVISSMVDAIMI
                     RVSSHEDIQTFSEHSSVPIINALSDESHPCQLLADMMTYQEYNGSIANKTVAWIGDGN
                     NMCHTYIQAAKSFNFKLNIAAPKNYQPNQSFIEKYANHIHLFTDIKTACKEVDLIVTD
                     VWASMGQETEQIKREIAFKDFQVDTVLMSKAKPTAVFMHCLPAHRGKEVSANVIDSNQ
                     SLVWSEAENRLHVQKALLLYLLN"
     misc_feature    complement(427934..428827)
                     /gene="argF"
                     /locus_tag="COSY_0418"
                     /note="ornithine carbamoyltransferase; Provisional;
                     Region: PRK00779"
                     /db_xref="CDD:234835"
     misc_feature    complement(428399..428821)
                     /gene="argF"
                     /locus_tag="COSY_0418"
                     /note="Aspartate/ornithine carbamoyltransferase,
                     carbamoyl-P binding domain; Region: OTCace_N; pfam02729"
                     /db_xref="CDD:217204"
     misc_feature    complement(427937..428383)
                     /gene="argF"
                     /locus_tag="COSY_0418"
                     /note="Aspartate/ornithine carbamoyltransferase, Asp/Orn
                     binding domain; Region: OTCace; pfam00185"
                     /db_xref="CDD:215776"
     gene            complement(428841..429998)
                     /gene="argD"
                     /locus_tag="COSY_0419"
                     /db_xref="GeneID:5172147"
     CDS             complement(428841..429998)
                     /gene="argD"
                     /locus_tag="COSY_0419"
                     /EC_number="2.6.1.11"
                     /note="catalyzes the formation of N-acetyl-l-glutamate
                     5-semialdehyde from 2-oxoglutarate and
                     N(2)-acetyl-L-ornithine"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine aminotransferase"
                     /protein_id="YP_001219262.1"
                     /db_xref="GI:148244568"
                     /db_xref="GeneID:5172147"
                     /translation="MSYLMSNYTPLKVTFVKGVGCYLIDDKDEQYLDALCGVGVVGLG
                     HCHQDITKTIQTQAANLLHTSNWYHIQYQEDLAEKLCQLSNMDKAFFANSGAEANEAA
                     IKIVRLHGHANHINNPTILTANQSFHGRTMATLSATGNPKIQEGFTPLVSNFIYFDFN
                     NIKAIKAHENNNNIVAVMLEPIQGESGIIIPDKNYLNQVQEICNNNNWLLILDEIQTG
                     IGRTGKLFAHNYNNITPDLLTLAKGLGNGIPIGACLAKGKASQILTPGTHGSTFGGNP
                     LACKTALTVLEIIEKDNILDNVLVMGEYIISSFRNKLKNSNKVFEIRSKGLMIAIELN
                     QDCSTLLQKALNNKLLINITGQTIRLLPPLIINQYDADILIDKVSNLINTL"
     misc_feature    complement(428844..429998)
                     /gene="argD"
                     /locus_tag="COSY_0419"
                     /note="acetylornithine aminotransferase; Provisional;
                     Region: PRK02627"
                     /db_xref="CDD:235056"
     misc_feature    complement(428865..429992)
                     /gene="argD"
                     /locus_tag="COSY_0419"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     Region: OAT_like; cd00610"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(429273..429275,429351..429356,
                     429360..429362,429459..429461,429609..429611,
                     429615..429620,429711..429719))
                     /gene="argD"
                     /locus_tag="COSY_0419"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(429273..429275,429351..429353,
                     429360..429362,429459..429461,429615..429620,
                     429711..429716))
                     /gene="argD"
                     /locus_tag="COSY_0419"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99735"
     misc_feature    complement(429273..429275)
                     /gene="argD"
                     /locus_tag="COSY_0419"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     gene            complement(430066..430269)
                     /locus_tag="COSY_0420"
                     /db_xref="GeneID:5172143"
     CDS             complement(430066..430269)
                     /locus_tag="COSY_0420"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219263.1"
                     /db_xref="GI:148244569"
                     /db_xref="GeneID:5172143"
                     /translation="MIATSQHSNELSAKRIVLQNTFKAHTQVNGFSYKDWINPPAGSF
                     YEGYKKKLDEINNEMAPPLTYQS"
     gene            430426..430734
                     /locus_tag="COSY_0421"
                     /db_xref="GeneID:5172569"
     CDS             430426..430734
                     /locus_tag="COSY_0421"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 modulation protein"
                     /protein_id="YP_001219264.1"
                     /db_xref="GI:148244570"
                     /db_xref="GeneID:5172569"
                     /translation="MQLNISGHHLDITEAIKQHSLTKLNKIKNHFNQVININMILEVK
                     KDVQKAEAIIHVSGADLFAKAESFDMYNSIDQMVNKLDVQIRKHKEKLNNHRKKLTTI
                     "
     misc_feature    430429..430698
                     /locus_tag="COSY_0421"
                     /note="RaiA (&quot;ribosome-associated inhibitor A&quot;,
                     also known as Protein Y (PY), YfiA, and SpotY,  is a
                     stress-response protein that binds the ribosomal subunit
                     interface and arrests translation by interfering with
                     aminoacyl-tRNA binding to the ribosomal...; Region: RaiA;
                     cd00552"
                     /db_xref="CDD:238308"
     misc_feature    order(430435..430437,430441..430443,430447..430449,
                     430501..430503,430510..430512,430528..430533,
                     430543..430545,430555..430557,430582..430584,
                     430591..430602,430609..430611,430615..430617,
                     430624..430626,430630..430632,430639..430641,
                     430681..430686,430696..430698)
                     /locus_tag="COSY_0421"
                     /note="30S subunit binding site; other site"
                     /db_xref="CDD:238308"
     gene            430781..432112
                     /gene="mgtE"
                     /locus_tag="COSY_0422"
                     /db_xref="GeneID:5172478"
     CDS             430781..432112
                     /gene="mgtE"
                     /locus_tag="COSY_0422"
                     /note="Mg2+ transporter-E (MgtE) family"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter MgtE"
                     /protein_id="YP_001219265.1"
                     /db_xref="GI:148244571"
                     /db_xref="GeneID:5172478"
                     /translation="MLEVENTSFKDCLQKLIKFLEHLKYEEAISYLVELHPIEIARLL
                     ESIPPKDRIQIWLNIDIGIKGDIIKNLNENVQSQLLSKMDVVDIVKTIEVLDMDDLPE
                     SKIHNLLLILDYKHKDHLKQILSYPEDSAAGLMNIDIITVRGNVTVGTVIRYLRLLKE
                     MPIDTDQVFVVNKSYQYLGSIYISTLLTNEAEQNIDLLINKKSKPILATTIDNEVASL
                     FEQRNLISAPVVDESNQLIGRITIDDVVDIIRDEAEHSVMSMAGLNEEEDVFSPVIQS
                     AKRRSIWLGINLITVFIAVFFIGLFEATLQGKITLAILMPVVASMGGIAGTQTLILVT
                     RGIATGRVTEANLKVLMNKEVVIGVLNGIFWSLIISVVTYIWFTDLMLSLVIALAIIV
                     NLIFAAFSGAFLPLLLIKFKIDPALAGGVILTTITDVIGFLAFLSLATLIV"
     misc_feature    430820..432106
                     /gene="mgtE"
                     /locus_tag="COSY_0422"
                     /note="Mg/Co/Ni transporter MgtE (contains CBS domain)
                     [Inorganic ion transport and metabolism]; Region: MgtE;
                     COG2239"
                     /db_xref="CDD:225148"
     misc_feature    430883..431173
                     /gene="mgtE"
                     /locus_tag="COSY_0422"
                     /note="MgtE intracellular N domain; Region: MgtE_N;
                     smart00924"
                     /db_xref="CDD:214915"
     misc_feature    431201..431494
                     /gene="mgtE"
                     /locus_tag="COSY_0422"
                     /note="This cd contains two tandem repeats of the
                     cystathionine beta-synthase (CBS pair) domain in the
                     magnesium transporter, MgtE.  MgtE and its homologs are
                     found in eubacteria, archaebacteria, and eukaryota.
                     Members of this family transport Mg2+ or other...; Region:
                     CBS_pair_Mg_transporter; cd04606"
                     /db_xref="CDD:239979"
     misc_feature    431720..432097
                     /gene="mgtE"
                     /locus_tag="COSY_0422"
                     /note="Divalent cation transporter; Region: MgtE; cl00786"
                     /db_xref="CDD:242091"
     gene            complement(432432..433805)
                     /locus_tag="COSY_0423"
                     /db_xref="GeneID:5172077"
     CDS             complement(432432..433805)
                     /locus_tag="COSY_0423"
                     /EC_number="5.4.2.8"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="YP_001219266.1"
                     /db_xref="GI:148244572"
                     /db_xref="GeneID:5172077"
                     /translation="MNISQSIFKAYDIRGIAKDDLTPENVKLLGLAIGSESISKYERN
                     IVIGRDGRLSSFDLMQALTEGLKKSGCHIVDIGMVVTPLVYFATHTKASTSGVMITGS
                     HNPPEYNGFKIIIAGETLSGERIQALYQRIQIGDFSSGHGTSIKVNIEEDYIKRITHD
                     IKLEKPFSIVVDAGNGVAGNIAPKLFEQLGVKVTKLFCLIDGNFSNHHPDPSKLHNLK
                     YIIKEVKHTGADMGFSFDGDGDRLGLIDNKGNVIWADRQMILYSRDILKRNKGAKIVF
                     DVKCSSLLSKDIIKHSGEAIMSRTGHSFIKAKLKETGAALGGEMSGHIFFKERWYGFD
                     DALYTGARLLEILSKTKKTCAEIFSELPDNFNTPEINIHFDQQGEQFNVMNKLAANVD
                     FPNARITTIDGIRVDYDNGWGLIRPSNTTPCLVLRFEADSQEVLNEIQERFRIWLKSN
                     NISTQYF"
     misc_feature    complement(432459..433805)
                     /locus_tag="COSY_0423"
                     /note="Phosphomannomutase [Carbohydrate transport and
                     metabolism]; Region: {ManB}; COG1109"
                     /db_xref="CDD:224034"
     misc_feature    complement(432465..433787)
                     /locus_tag="COSY_0423"
                     /note="The phosphomannomutase/phosphoglucomutase (PMM/PGM)
                     bifunctional enzyme catalyzes the reversible conversion of
                     1-phospho to 6-phospho-sugars (e.g. between
                     mannose-1-phosphate and mannose-6-phosphate or
                     glucose-1-phosphate and glucose-6-phosphate) via a...;
                     Region: PMM_PGM; cd03089"
                     /db_xref="CDD:100091"
     misc_feature    complement(order(432546..432554,432558..432560,
                     432837..432839,432843..432845,432849..432851,
                     432900..432908,432969..432971,433083..433088,
                     433092..433094,433098..433100,433470..433472,
                     433494..433502,433764..433766,433773..433775,
                     433779..433781))
                     /locus_tag="COSY_0423"
                     /note="active site"
                     /db_xref="CDD:100091"
     misc_feature    complement(order(432546..432554,432558..432560,
                     432837..432839,432843..432845,432849..432851,
                     432900..432902,432906..432908,432969..432971,
                     433083..433085,433500..433502,433764..433766,
                     433773..433775))
                     /locus_tag="COSY_0423"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100091"
     misc_feature    complement(order(433086..433088,433092..433094,
                     433098..433100,433500..433502))
                     /locus_tag="COSY_0423"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:100091"
     gene            433862..434230
                     /gene="rseC"
                     /locus_tag="COSY_0424"
                     /db_xref="GeneID:5172447"
     CDS             433862..434230
                     /gene="rseC"
                     /locus_tag="COSY_0424"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseC"
                     /protein_id="YP_001219267.1"
                     /db_xref="GI:148244573"
                     /db_xref="GeneID:5172447"
                     /translation="MKEQFKVITINNEIMTLEVNRSSGCHGCEASSSCGIGILTNHYS
                     VFNRPCRDNISAGDFVTLEISSSELFLRAFQLYILPLLSLFISGVLGSILYTVNEMGQ
                     IVFALIGFFISFVFIKYFIK"
     misc_feature    433880..434227
                     /gene="rseC"
                     /locus_tag="COSY_0424"
                     /note="Positive regulator of sigma(E), RseC/MucC; Region:
                     RseC_MucC; pfam04246"
                     /db_xref="CDD:202942"
     gene            434291..436942
                     /gene="aceE"
                     /locus_tag="COSY_0425"
                     /db_xref="GeneID:5172351"
     CDS             434291..436942
                     /gene="aceE"
                     /locus_tag="COSY_0425"
                     /EC_number="1.2.4.1"
                     /note="E1 component; part of pyruvate dehydrogenase; forms
                     a complex with DlaT and LpdC"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase subunit E1"
                     /protein_id="YP_001219268.1"
                     /db_xref="GI:148244574"
                     /db_xref="GeneID:5172351"
                     /translation="MLVQDIDPLETQEWLEAFKSVVRIEGDDRVKFLLNQLMNMAYHE
                     GIDLPTDVNTSYLNSISKEKEVVTDINKDIEERISAIVRWNAMVMVVKANQLPYDLGG
                     HIASFASSATLYEVGFNHFYRGPDAHQGADLVFFQGHISPGIYSRAYLEGRITEDQML
                     KFRQEVGKDGLSSYPHPWLMPDFWQFPTVSMGLGPIMAIFQARFMKYLHHREIKQTDK
                     RTVWAYLGDGETDEPEALGAISMAGREKLDNLIFVINCNLQRLDGPVRGNGKIIQELE
                     GVFHGSGWNVIKVIWGGKWDELFAKDTQGLLKKRMEEVVDGEYQAYKAKDGAYVRKHF
                     FGKYPELLAMVKDMSDDEIYHLDRGGHDPYKVFQVYHSAKACHDKPTVILAKTVKGYG
                     MGEAGEGQNTTHSQKKIGLKQVETFAKRFDVPVTEEDVKALNFYKPALDSEEMVYMRA
                     KRKKLGGSLPVRAFDLEQIKIPKLNVFETLLKSSGDRKMSTTMVFNRVITLLVRDKQL
                     GPKIVPIIPDEARTFGMEGLFRQLGIYSASGQLYQPEDSDKVMWYKEDKKGQVLQEGI
                     NEAGAISDWIAAATAYATHNTTMIPFYIYYSKFGFQRVGDLIWAAGDMQAKGFLIGGT
                     AGRTTLNGEGLQHQDGDSQLVANTIPNCISYDPAYGYELMVIIHSGLYRMYEKHENIF
                     YYITVMNELYTHPEMPKNSEQGIIKGMYKLKTIGKSIIEVQLMGSGTILREVEKAAKM
                     LADDWGVKSSIWSVTSFNELTREAQAIDRVNRFNTSGITQVPYITKCLEDANGPIIVA
                     TDYMRNFAEQVRKYVPNRYEVLGTDGFGRSDSRAALREFFEVNAKYITIVALKALSDE
                     GEIDISIFTKAIKKYKFNISKPNPMTV"
     misc_feature    434291..436939
                     /gene="aceE"
                     /locus_tag="COSY_0425"
                     /note="pyruvate dehydrogenase subunit E1; Reviewed;
                     Region: aceE; PRK09405"
                     /db_xref="CDD:236500"
     misc_feature    434507..435661
                     /gene="aceE"
                     /locus_tag="COSY_0425"
                     /note="Thiamine pyrophosphate (TPP) family, E1 of E. coli
                     PDC-like subfamily, TPP-binding module; composed of
                     proteins similar to the E1 component of the Escherichia
                     coli pyruvate dehydrogenase multienzyme complex (PDC). PDC
                     catalyzes the oxidative...; Region: TPP_E1_EcPDC_like;
                     cd02017"
                     /db_xref="CDD:238975"
     misc_feature    order(434582..434590,434777..434788,434807..434812,
                     434816..434818,434822..434824,434849..434851,
                     434855..434863,434981..434992,434999..435001,
                     435008..435010,435020..435022,435068..435076,
                     435086..435088,435110..435112,435119..435124,
                     435131..435133)
                     /gene="aceE"
                     /locus_tag="COSY_0425"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238975"
     misc_feature    order(434606..434608,434699..434701,434705..434707,
                     434855..434857,434861..434863,434969..434977,
                     434984..434986,435059..435061,435065..435067,
                     435455..435457)
                     /gene="aceE"
                     /locus_tag="COSY_0425"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238975"
     gene            complement(437037..439124)
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /db_xref="GeneID:5172404"
     CDS             complement(437037..439124)
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /EC_number="2.7.7.8"
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide phosphorylase/polyadenylase"
                     /protein_id="YP_001219269.1"
                     /db_xref="GI:148244575"
                     /db_xref="GeneID:5172404"
                     /translation="MNIKTKSFTMGKHIVTLETGRIARQAHGAVLASMDDTQVLVTVV
                     SSKETRPGQDFFPLSVDYIEKTYSTGKIPGSFLKREARPSEKETLTSRLIDRTIRPLF
                     PNGFMNEIQVLITVVSANSEVNPDIISMLGVSAALSISGVPFSRPIGGSRVGYSNGEY
                     ILNPTYIELTNSDLDMVVAGTDEAVLMVESEANELSEEIMLGAVVYAHEQYQVAITNI
                     AEFTTEVGMQKWDWIAPITNEVLLSDIKSKFGKEINKAYQIKEKLDRHAKIDNIRMAA
                     IEALENENENGNSAEEVSKYFKEVEKSTVRERILNNDSRIDGRNNETVRELKIETGIL
                     KNTHGSALFTRGETQALVVTTLGPKSDAQLIEKLESPERQNNYFLLHYNFPPYCVGET
                     GRLATIKRREIGHGHLARRGITACLPSIEEFPYTVRVVSEITESNGSSSMASVCGSSL
                     SLMDAGVPIKAPIAGIAMGLVKENDRFTVLTDILGDEDHLGDMDFKVAGTSRGVNALQ
                     MDIKIQSITHEIMEIALKQAKEARLNILGQMNQVICEPNTSNKNTPKTTIIKIKTDKI
                     RDLIGRGGETIKGIISTSCASIDVDDSGNVNIFSNNQKSFDTAVQMVKDVTAIPEVNK
                     VYTGKVVKIVEFGAFINIMPNQDGLLHISEISHERVEKVKDHIREGDKIDVKVIGLDR
                     GRIKLSRKVLLEK"
     misc_feature    complement(437046..439124)
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="polynucleotide phosphorylase/polyadenylase;
                     Provisional; Region: PRK11824"
                     /db_xref="CDD:236995"
     misc_feature    complement(438429..439115)
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="Polyribonucleotide nucleotidyltransferase, repeat
                     1; Region: RNase_PH_PNPase_1; cd11363"
                     /db_xref="CDD:206768"
     misc_feature    complement(order(439011..439013,439020..439022,
                     439026..439028,439032..439034,439062..439064,
                     439071..439073,439077..439079,439104..439106,
                     439110..439112))
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="RNase E interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:206768"
     misc_feature    complement(order(438762..438776,438786..438788,
                     438792..438794,438798..438800,438873..438875,
                     438885..438899,438906..438917,438921..438932,
                     438936..438938,438942..438944,438987..438989,
                     438993..438995,438999..439001,439005..439007,
                     439032..439034,439047..439064))
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:206768"
     misc_feature    complement(438168..438404)
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="Polyribonucleotide nucleotidyltransferase, RNA
                     binding domain; Region: PNPase; pfam03726"
                     /db_xref="CDD:217697"
     misc_feature    complement(437487..438158)
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="Polyribonucleotide nucleotidyltransferase, repeat
                     2; Region: RNase_PH_PNPase_2; cd11364"
                     /db_xref="CDD:206769"
     misc_feature    complement(order(437496..437501,437511..437513,
                     437523..437525,437535..437537,438120..438122,
                     438129..438158))
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="RNase E interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:206769"
     misc_feature    complement(order(437817..437825,437829..437831,
                     437835..437837,437841..437843,437931..437933,
                     437937..437939,437946..437954,437958..437969,
                     437976..437978,437982..437984,438036..438044,
                     438054..438062,438066..438068,438072..438074,
                     438084..438089,438111..438125,438135..438137,
                     438141..438143))
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:206769"
     misc_feature    complement(order(437595..437597,437601..437603,
                     437637..437639,437643..437645,437661..437663,
                     437802..437810,437910..437912,437922..437924,
                     437973..437975,437979..437981))
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="active site"
                     /db_xref="CDD:206769"
     misc_feature    complement(437283..>437426)
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="Polynucleotide phosphorylase (PNPase) K homology
                     RNA-binding domain (KH). PNPase is a polyribonucleotide
                     nucleotidyl transferase that degrades mRNA in prokaryotes
                     and plant chloroplasts. The C-terminal region of PNPase
                     contains domains homologous to...; Region: PNPase_KH;
                     cd02393"
                     /db_xref="CDD:239086"
     misc_feature    complement(order(437355..437366,437379..437384,
                     437391..437396,437403..437417,437421..437426))
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="putative nucleic acid binding region [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239086"
     misc_feature    complement(437403..437414)
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="G-X-X-G motif; other site"
                     /db_xref="CDD:239086"
     misc_feature    complement(437058..437258)
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="S1_PNPase: Polynucleotide phosphorylase (PNPase),
                     ), S1-like RNA-binding domain. PNPase  is a
                     polyribonucleotide nucleotidyl transferase that degrades
                     mRNA. It is a trimeric multidomain protein. The C-terminus
                     contains the S1 domain which binds ssRNA; Region:
                     S1_PNPase; cd04472"
                     /db_xref="CDD:239918"
     misc_feature    complement(order(437172..437174,437178..437180,
                     437208..437210,437232..437234))
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:239918"
     misc_feature    complement(437112..437117)
                     /gene="pnp"
                     /locus_tag="COSY_0426"
                     /note="domain interface; other site"
                     /db_xref="CDD:239918"
     gene            complement(439839..441299)
                     /gene="guaB"
                     /locus_tag="COSY_0427"
                     /db_xref="GeneID:5171824"
     CDS             complement(439839..441299)
                     /gene="guaB"
                     /locus_tag="COSY_0427"
                     /EC_number="1.1.1.205"
                     /note="inosine-5'-monophosphate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="YP_001219270.1"
                     /db_xref="GI:148244576"
                     /db_xref="GeneID:5171824"
                     /translation="MNLLKTAYTFDDVLLVPEYSKIIPKKVNLITQLTKNITLNIPIL
                     SAAMDTVTESKLAIAIAQEGGIGIIHKNISVEEQANEVHRVKRFESGIIKEPITISLK
                     ATIADVLKMQQQYNISALPVVEGNTIKGLVTGRDVRFKTRLNELVKNVMTPQNKLITV
                     KEGTNINKVRSLLQKHRIERIIITDDTFNLKGMINVSDIQKSTDFPNACKDSEERLRV
                     GAAVGVGAGTSKRIDALIEAGVDVIVIDTAHGHSQGVLNRVAETKNKHPNLSIIAGNI
                     ATGGAALDLIKAGADCVKVGIGPGSICTTRIVAGVGIPQISAISEVADALKDTGIPLI
                     ADGGIRYSGDIAKALAAGAYCVMLGSMLAGTEESPGEVELYQGRSYKSYRGMGSLGAM
                     NQAHGSSDRYFQSDSKADKLVPEGVEGRVPFKGSIRPIIHQMIGGVKSSMGYIGCDTL
                     EKMRTNSQFVQVTSAGMVESHVHDVSITKEASNYHQ"
     misc_feature    complement(439845..441299)
                     /gene="guaB"
                     /locus_tag="COSY_0427"
                     /note="inosine 5&apos;-monophosphate dehydrogenase;
                     Reviewed; Region: PRK05567"
                     /db_xref="CDD:235507"
     misc_feature    complement(<441042..441281)
                     /gene="guaB"
                     /locus_tag="COSY_0427"
                     /note="TIM barrel proteins share a structurally conserved
                     phosphate binding motif and in general share an eight
                     beta/alpha closed barrel structure. Specific for this
                     family is the conserved phosphate binding site at the
                     edges of strands 7 and 8. The phosphate...; Region:
                     TIM_phosphate_binding; cl17186"
                     /db_xref="CDD:247740"
     misc_feature    complement(440694..441023)
                     /gene="guaB"
                     /locus_tag="COSY_0427"
                     /note="This cd contains two tandem repeats of the
                     cystathionine beta-synthase (CBS pair) domains in the
                     inosine 5&apos; monophosphate dehydrogenase (IMPDH)
                     protein.  IMPDH is an essential enzyme that catalyzes the
                     first step unique to GTP synthesis, playing a...; Region:
                     CBS_pair_IMPDH; cd04601"
                     /db_xref="CDD:239974"
     misc_feature    complement(439914..>440657)
                     /gene="guaB"
                     /locus_tag="COSY_0427"
                     /note="IMPDH: The catalytic domain of the inosine
                     monophosphate dehydrogenase. IMPDH catalyzes the
                     NAD-dependent oxidation of inosine 5&apos;-monophosphate
                     (IMP) to xanthosine 5&apos; monophosphate (XMP). It is a
                     rate-limiting step in the de novo synthesis of...; Region:
                     IMPDH; cd00381"
                     /db_xref="CDD:238223"
     misc_feature    complement(order(440052..440057,440139..440147,
                     440151..440153,440220..440225,440286..440288,
                     440292..440294,440391..440399))
                     /gene="guaB"
                     /locus_tag="COSY_0427"
                     /note="active site"
                     /db_xref="CDD:238223"
     gene            complement(441299..441958)
                     /locus_tag="COSY_0428"
                     /db_xref="GeneID:5171823"
     CDS             complement(441299..441958)
                     /locus_tag="COSY_0428"
                     /note="SH3 domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219271.1"
                     /db_xref="GI:148244577"
                     /db_xref="GeneID:5171823"
                     /translation="MNLIKYLLLTPILFSTLISIVNAKSFVYITDQVDIPMREDKSFN
                     NNIIRSLSSGAKLYILQATKDGWTQVKYKDSIGWVISRYLSNNPPARVKLDKFKKKYN
                     SNQLLSIKQGKRNTELEKQVKILKNQNTKLFIQKNKSKAEKQHIEKIYKDALKLEHSN
                     EKLSTKILQLKAEIQLLENNNTATQNYSSRNWFITGSLVLFFGAIIGLILSNFVNRRR
                     Y"
     misc_feature    complement(441305..441877)
                     /locus_tag="COSY_0428"
                     /note="SH3 domain protein; Region: SH3_and_anchor;
                     TIGR04211"
                     /db_xref="CDD:234501"
     misc_feature    complement(441704..441850)
                     /locus_tag="COSY_0428"
                     /note="Bacterial SH3 domain; Region: SH3_3; cl17532"
                     /db_xref="CDD:248086"
     gene            complement(441955..444702)
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /db_xref="GeneID:5172224"
     CDS             complement(441955..444702)
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /EC_number="6.1.1.9"
                     /codon_start=1
                     /transl_table=11
                     /product="valyl-tRNA synthetase"
                     /protein_id="YP_001219272.1"
                     /db_xref="GI:148244578"
                     /db_xref="GeneID:5172224"
                     /translation="MEKTYNPEQIEAKFSLLWEDKNLFSSNSNTTSKNAYCIMLPPPN
                     VTGSLHMGHAFQHTIMDILTRYHRANGEQTLWQPGTDHAGIATQMVVERQLATQDMTR
                     HELGREKFTQKIWDWKAQSGDTITSQMRRLGFSVDWEKNRFTMDNGLSNAVKKVFIQL
                     FKEGLIYRGKRLVNWDPILHTAVSDLEVINTEEQSSLWYIRYPVTNTNEVMIIATTRP
                     ETMLGDSAIAVHPNDKRYTHLIGKTVDLPLTNRKIPIIKDDYVDMKFSTGCVKITPAH
                     DFNDYEVGFRHNLDVINILTDDAKINNGVNSAYTDMDRFKARKQIIQDLDNQGLLEKI
                     EPHKLMIPRGDRTNAIIEPYLTDQWFVKIKPLVQPAIDAVKNRDIRFIPENWSKTYFN
                     WMNNIQDWCISRQIWWGHRIPAWYDEKGNIFVADSLKQAQEQAGEGITLIQDKDVLDT
                     WFSSALWPFSTLGWPEKTPDLSRFYPTNVLVTGFDIIFFWVARMIMFGLKFTGEVPFK
                     DIYITGLIKDGQGQKMSKSKGNVLDPIDLINGITLKNLLEKRTQGLMQIKMAEKIKKQ
                     TRKEFANGIPAFGTDALRFTFATLASFSCDIKFDIKRVEGYRNFCNKLWNASRFVLMN
                     LKGKTIDTNAQLSTADEWILSRLQNTKINVEKHLSDYRIDLMSQTLYEFIWHDYCDWY
                     LELSKSLLQNNKTKTGTQAILIKVLSEIVTLLHPIIPFITEEIFEQCNVITGHDNTSL
                     IIQPYPKIINNLISAKAEAEMKWLQTFILRIRQIRGEMNISPLKWLPCFVQSFNSKDE
                     QYLTNNINILNSLAKIESINKLTTTEQAPESATALVNDMKIFIPLAGLIDKSQEITRL
                     NKEIKKLKKMKSQFKSKLDNEKFIKGAPKTIINIEKERLATTLSAIHDLNNQLNKISS
                     L"
     misc_feature    complement(441961..444702)
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="valyl-tRNA synthetase; Reviewed; Region: valS;
                     PRK05729"
                     /db_xref="CDD:235582"
     misc_feature    complement(<444094..444597)
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="nucleotidyl transferase superfamily; Region:
                     nt_trans; cl00015"
                     /db_xref="CDD:241550"
     misc_feature    complement(444544..444555)
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="active site"
                     /db_xref="CDD:173912"
     misc_feature    complement(444544..444555)
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173912"
     misc_feature    complement(order(444544..444546,444553..444555))
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173912"
     misc_feature    complement(443728..444108)
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="Leucyl-tRNA synthetase, Domain 2; Region:
                     tRNA-synt_1_2; pfam13603"
                     /db_xref="CDD:222257"
     misc_feature    complement(442906..>443673)
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="catalytic core domain of valyl-tRNA synthetases;
                     Region: ValRS_core; cd00817"
                     /db_xref="CDD:185677"
     misc_feature    complement(order(443131..443133,443155..443166,
                     443233..443235,443245..443250,443254..443259,
                     443341..443343,443350..443352))
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="active site"
                     /db_xref="CDD:185677"
     misc_feature    complement(443122..443136)
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:185677"
     misc_feature    complement(442558..442908)
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="Anticodon-binding domain of valyl tRNA synthetases;
                     Region: Anticodon_Ia_Val; cd07962"
                     /db_xref="CDD:153416"
     misc_feature    complement(order(442642..442644,442651..442656,
                     442678..442680,442699..442701,442708..442710,
                     442843..442848,442852..442857,442864..442869,
                     442876..442881,442885..442887,442894..442899,
                     442903..442905))
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="tRNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:153416"
     misc_feature    complement(order(442642..442644,442651..442656,
                     442666..442668,442843..442848,442852..442857,
                     442864..442866))
                     /gene="valS"
                     /locus_tag="COSY_0429"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:153416"
     gene            complement(445145..445450)
                     /locus_tag="COSY_0430"
                     /db_xref="GeneID:5172552"
     CDS             complement(445145..445450)
                     /locus_tag="COSY_0430"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219273.1"
                     /db_xref="GI:148244579"
                     /db_xref="GeneID:5172552"
                     /translation="MFKAGMTDMMKKAQQIQNNMKQAQSEIKNLSATGKAAGGCVEII
                     LNGEHIVTNITILDEVMSDKELLEDLILNAMNDAVKQIANASSAKMKTITGDMNLPF"
     misc_feature    complement(445151..445444)
                     /locus_tag="COSY_0430"
                     /note="hypothetical protein; Validated; Region: PRK00153"
                     /db_xref="CDD:234669"
     gene            complement(445443..447014)
                     /gene="dnaX"
                     /locus_tag="COSY_0431"
                     /db_xref="GeneID:5172376"
     CDS             complement(445443..447014)
                     /gene="dnaX"
                     /locus_tag="COSY_0431"
                     /EC_number="2.7.7.7"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III tau and gamma subunit"
                     /protein_id="YP_001219274.1"
                     /db_xref="GI:148244580"
                     /db_xref="GeneID:5172376"
                     /translation="MSKHYQVLARKYRPHSFTELVGQTNTKKTLINALNANNVHHGFL
                     FTGTRGVGKTSIARIFAKSINCEKGVSSTPCGKCSTCIEIDKGQSIDLIELDAASHTG
                     VDNMRSILENTQYMPSKNRYKIYLIDEVHMLSNSSFNALLKTLEEPPEHVKFLLATTN
                     PQKLPVTILSRCLQFTLQQLTHDEILGQLKFIMDSEALSYEELALSQIANFGKGSMRD
                     ALSLLDQSISYGKGTVTSADIKTMLGLVHHGDIITLTTHLFNQDAKSVINFIKDLSHR
                     GENLNNALKDLSSLFHKISIAQIVDTKSDRTTKNLSKQISNFDLQIFYQMSINGSKDM
                     ALAPSDQIGFEMTLLRMLAFRSDNQPNTEKKTLKIKSKVKTPVLIEKKEISDITKPKI
                     LNINNQQQWETLILSLEFKGSVKMLVENTLFDNVNNTTLTLTLDNQFTNLLNNYVQKS
                     MLTTLRKKFSTLNLVINLGKLNVQTLAQKKTQAHSKKITKMQTKFLNDEGVQKLEKIF
                     DTKINVNSIKEIKHV"
     misc_feature    complement(445455..447002)
                     /gene="dnaX"
                     /locus_tag="COSY_0431"
                     /note="DNA polymerase III subunits gamma and tau;
                     Provisional; Region: PRK14969"
                     /db_xref="CDD:237873"
     misc_feature    complement(446499..446954)
                     /gene="dnaX"
                     /locus_tag="COSY_0431"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(446853..446876)
                     /gene="dnaX"
                     /locus_tag="COSY_0431"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(446538..446540,446631..446633,
                     446850..446873))
                     /gene="dnaX"
                     /locus_tag="COSY_0431"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(446628..446645)
                     /gene="dnaX"
                     /locus_tag="COSY_0431"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(<446346..>446600)
                     /gene="dnaX"
                     /locus_tag="COSY_0431"
                     /note="DNA polymerase III subunit delta&apos;; Validated;
                     Region: PRK08485"
                     /db_xref="CDD:236274"
     misc_feature    complement(446502..446504)
                     /gene="dnaX"
                     /locus_tag="COSY_0431"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(445947..446315)
                     /gene="dnaX"
                     /locus_tag="COSY_0431"
                     /note="DNA polymerase III subunits gamma and tau domain
                     III; Region: DNA_pol3_gamma3; pfam12169"
                     /db_xref="CDD:152604"
     gene            complement(448280..449113)
                     /locus_tag="COSY_0432"
                     /db_xref="GeneID:5172294"
     CDS             complement(448280..449113)
                     /locus_tag="COSY_0432"
                     /EC_number="2.6.1.21"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase, class IV"
                     /protein_id="YP_001219275.1"
                     /db_xref="GI:148244581"
                     /db_xref="GeneID:5172294"
                     /translation="MVFLNGEFIKKNQAHISVMDRGFLFGDGVYEVIPIYNGKIFRLD
                     EHLLRLQTSLDSIKIKNPYSPKKWDSILNKLLKFYNNQEQSIYLQISRGISNKRQHSF
                     SNLTPTVYIESNILLTKTKETLRTGFSAITQPDIRWSRCDIKSTSLLANVMYSQQAKE
                     KNVEEIILYQNTQVTEGATSNVFMIKNNTLYTHPTNVHILSGITRDLVLESAKAYHIS
                     IQETSFSIDELNTADELWISSSTREIMPITKVDNKLINNGHIGNVWSRVYDYYQSLKN
                     V"
     misc_feature    complement(448301..449113)
                     /locus_tag="COSY_0432"
                     /note="Branched-chain amino acid
                     aminotransferase/4-amino-4-deoxychorismate lyase [Amino
                     acid transport and metabolism / Coenzyme metabolism];
                     Region: IlvE; COG0115"
                     /db_xref="CDD:223193"
     misc_feature    complement(448301..449107)
                     /locus_tag="COSY_0432"
                     /note="D-Alanine aminotransferase (D-AAT_like): D-amino
                     acid aminotransferase catalyzes transamination between
                     D-amino acids and their respective alpha-keto acids. It
                     plays a major role in the synthesis of bacterial cell wall
                     components like D-alanine and...; Region: D-AAT_like;
                     cd01558"
                     /db_xref="CDD:238799"
     misc_feature    complement(order(448577..448579,448634..448636,
                     448646..448651,448658..448663,448667..448681,
                     448778..448780,448790..448792,448841..448843,
                     448847..448849,448853..448855,449024..449026,
                     449033..449062,449066..449071))
                     /locus_tag="COSY_0432"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238799"
     misc_feature    complement(order(448394..448396,448502..448507,
                     448586..448588,448670..448672,448682..448684,
                     448967..448969,449024..449026,449039..449041))
                     /locus_tag="COSY_0432"
                     /note="substrate-cofactor binding pocket; other site"
                     /db_xref="CDD:238799"
     misc_feature    complement(order(448394..448396,448502..448504,
                     448682..448684,448967..448969,449024..449026))
                     /locus_tag="COSY_0432"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238799"
     misc_feature    complement(448682..448684)
                     /locus_tag="COSY_0432"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238799"
     gene            complement(449113..450240)
                     /locus_tag="COSY_0433"
                     /db_xref="GeneID:5172451"
     CDS             complement(449113..450240)
                     /locus_tag="COSY_0433"
                     /EC_number="3.4.16.4"
                     /note="penicillin-binding protein 5/6"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="YP_001219276.1"
                     /db_xref="GI:148244582"
                     /db_xref="GeneID:5172451"
                     /translation="MQNKLFIKFLTILICSFTLNIQAAIFITPKAPEISAVAYSIVDY
                     NSGKVIASNKQHYKRAPASLTKLMTAYVIFQLISNDRIKLEDEVRISKKAWKTGGSKS
                     FVEVGKTMKLETLLKGMIIQSGNDSAVALAEHIAGDESTFTTYMNKYARKLGMNNSQF
                     RNASGLPDNNQYTTAADIVLLATAIIKDFPQFYLWYSEKEFTYHGIKQYNRNKLLWND
                     HTVDGLKTGFTKKAGYNLVASAKRLGMRLISVVLGSSSVNDRTSQTQKILDYGFRFFE
                     TKTIRNIKKELPIANSTKNMLKVGTSKIISFTLARGQFKFSDQVIQLDTALSAPINKG
                     DVVGKLLIQFKGKTMASIPLIALEHAQQASFFSRMLETIGF"
     misc_feature    complement(449134..450216)
                     /locus_tag="COSY_0433"
                     /note="D-alanyl-D-alanine carboxypeptidase [Cell envelope
                     biogenesis, outer membrane]; Region: DacC; COG1686"
                     /db_xref="CDD:224600"
     misc_feature    complement(<449530..450207)
                     /locus_tag="COSY_0433"
                     /note="Beta-lactamase enzyme family; Region:
                     Beta-lactamase2; cl17872"
                     /db_xref="CDD:248426"
     misc_feature    complement(449167..449418)
                     /locus_tag="COSY_0433"
                     /note="Penicillin-binding protein 5, C-terminal domain;
                     Region: PBP5_C; smart00936"
                     /db_xref="CDD:198004"
     gene            complement(450774..451913)
                     /gene="rodA"
                     /locus_tag="COSY_0434"
                     /db_xref="GeneID:5172623"
     CDS             complement(450774..451913)
                     /gene="rodA"
                     /locus_tag="COSY_0434"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="YP_001219277.1"
                     /db_xref="GI:148244583"
                     /db_xref="GeneID:5172623"
                     /translation="MKLLSVAQIRYYWHYFKIDTPLFLLIIALSGFGLIVLYSASEGS
                     MQTMYKQAFHFALAICAMLIIAQIPPYELKRFSPYLMLFGIFLLFLVLFFGSNSGGAQ
                     RWLNFGFIRFQPSEIMKVIVPIAIASILSEKTFLPKLLPIFLSIVAIILIVILIAKQP
                     DLGTSLLIAASGFYVLFFSGVRIQIVKNNWLNFTLISSITMLGVYVLWNYLLIGYQKE
                     RIMTLFDPSSDPLGSGYHILQSKIAIGSGGLIGKGLGQGSQSHLNFLPEHTTDFIFAV
                     IAEELGFIGIIFLFTLYGLIIYRLLIISFQSEDNFSKLLGLSLTFVFFTYIFVNVGMV
                     SGLLPVVGVPLPMISYGGSSIITLMSSFGIIMAIRKHKTPSYLQK"
     misc_feature    complement(450798..451859)
                     /gene="rodA"
                     /locus_tag="COSY_0434"
                     /note="rod shape-determining protein RodA; Region:
                     rodA_shape; TIGR02210"
                     /db_xref="CDD:233780"
     gene            complement(451910..452308)
                     /locus_tag="COSY_0435"
                     /db_xref="GeneID:5172593"
     CDS             complement(451910..452308)
                     /locus_tag="COSY_0435"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219278.1"
                     /db_xref="GI:148244584"
                     /db_xref="GeneID:5172593"
                     /translation="MCFYSSNNRCNTMEFNQQEADYNSIISVKEYHVKLTHIQLKIPC
                     FISCSYYCEININHLNDINKISLFPLSNQDSINLLIIGTGLTHKFLHPKQQIAIRQMG
                     INTEIMNNKSACRSFNLLLSDARSVGLLLL"
     misc_feature    complement(451913..452239)
                     /locus_tag="COSY_0435"
                     /note="Mth938-like domain. The members of this family
                     include: Mth938, 2P1, Xcr35, Rpa2829, and several
                     uncharacterized sequences. Mth938 is a hypothetical
                     protein encoded by the Methanobacterium
                     thermoautotrophicum (Mth) genome. This protein
                     crystallizes as a...; Region: Mth938-like; cd00248"
                     /db_xref="CDD:238152"
     gene            452355..452804
                     /locus_tag="COSY_0436"
                     /db_xref="GeneID:5172689"
     CDS             452355..452804
                     /locus_tag="COSY_0436"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219279.1"
                     /db_xref="GI:148244585"
                     /db_xref="GeneID:5172689"
                     /translation="MSDSSNIDIYNADLSSGVTAFDTKNFTMAYQLLAPLATKGNAEA
                     LWRVGMMQMNGLGMVENQPLGFENFLQAAGKGHAFAHHMLGVAYMTGEGVEKDIIQSI
                     EWFKKGAKFGISGPMYTLGMLFEDGKEVKQDLEKAQFWFDKADRVSL"
     misc_feature    452394..>452789
                     /locus_tag="COSY_0436"
                     /note="FOG: TPR repeat, SEL1 subfamily [General function
                     prediction only]; Region: COG0790"
                     /db_xref="CDD:223861"
     misc_feature    452478..452585
                     /locus_tag="COSY_0436"
                     /note="Sel1 repeat; Region: Sel1; cl02723"
                     /db_xref="CDD:243158"
     misc_feature    452586..452690
                     /locus_tag="COSY_0436"
                     /note="Sel1-like repeats; Region: SEL1; smart00671"
                     /db_xref="CDD:214772"
     misc_feature    452703..452786
                     /locus_tag="COSY_0436"
                     /note="Sel1-like repeats; Region: SEL1; smart00671"
                     /db_xref="CDD:214772"
     gene            452817..454184
                     /gene="gltX"
                     /locus_tag="COSY_0437"
                     /db_xref="GeneID:5172692"
     CDS             452817..454184
                     /gene="gltX"
                     /locus_tag="COSY_0437"
                     /EC_number="6.1.1.17"
                     /note="Charges one glutamine molecule and pairs it to its
                     corresponding RNA trinucleotide during protein
                     translation"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA synthetase"
                     /protein_id="YP_001219280.1"
                     /db_xref="GI:148244586"
                     /db_xref="GeneID:5172692"
                     /translation="MIKSRFAPSPTGYLHIGGARTAFFAWIWAKKQHGKFVLRIENTD
                     LERSTQASVDAILQGIDWLGLNYDEGPLYQTDRFDRYKQIIQQLLDEKKAYYCECSKK
                     RLQILREELTKQGKKAKYDGCCRNKNLHTGVVRFNNPKEGIVVFNDVVKGKISINNQE
                     LDDLIIARSDNTPTYNLTVVVDDHDMKINIIIRGDDHINNTPKQINLYQALGWHLPEF
                     AHLPMILGNDGIRLSKRHGAVSIMAYRDAGFLPEALLNYLSRLGWSYGNQEIFSINKI
                     VQLFELKNINKASASFNQDKLLWFNQETIKSSSVKNLLSNLTWHLQNQEIIIKDTPNI
                     EIVVRYLQDRCKTLVNMAGELKMFYQDFDTFDEKLAKKFFKDKTPLKRLFVELEMLNT
                     WKADNIKQVVKQVCFELNIGFGRVGQPFRLALSGDGNAGSIDIVAELVGKNKALLRLK
                     MAIDF"
     misc_feature    452817..454175
                     /gene="gltX"
                     /locus_tag="COSY_0437"
                     /note="glutamyl-tRNA synthetase; Reviewed; Region: gltX;
                     PRK01406"
                     /db_xref="CDD:234953"
     misc_feature    452817..>453092
                     /gene="gltX"
                     /locus_tag="COSY_0437"
                     /note="catalytic core domain of discriminating
                     glutamyl-tRNA synthetase; Region: GluRS_core; cd00808"
                     /db_xref="CDD:173905"
     misc_feature    452859..452870
                     /gene="gltX"
                     /locus_tag="COSY_0437"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173905"
     misc_feature    <453309..453731
                     /gene="gltX"
                     /locus_tag="COSY_0437"
                     /note="catalytic core domain of discriminating
                     glutamyl-tRNA synthetase; Region: GluRS_core; cd00808"
                     /db_xref="CDD:173905"
     misc_feature    order(453339..453341,453351..453353,453393..453398,
                     453402..453407,453480..453485,453507..453512)
                     /gene="gltX"
                     /locus_tag="COSY_0437"
                     /note="active site"
                     /db_xref="CDD:173905"
     misc_feature    453507..453521
                     /gene="gltX"
                     /locus_tag="COSY_0437"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173905"
     gene            454200..456719
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /db_xref="GeneID:5172282"
     CDS             454200..456719
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /EC_number="2.7.7.59"
                     /codon_start=1
                     /transl_table=11
                     /product="[protein-PII] uridylyltransferase"
                     /protein_id="YP_001219281.1"
                     /db_xref="GI:148244587"
                     /db_xref="GeneID:5172282"
                     /translation="MIDLSLFKAQYQSLQDLIKEDFLNSPETAQALILYRSDGIDQLL
                     KDIWQSFNISDQLCLVAVGGYGRKELHPYSDIDLLILIPDGSHNTYQQDIASFLTFLW
                     DVNLEVGHATRDLKDCISVIDDLSVVTNLLESRVILGKVSLFYKMKAVIKSSVWSSQS
                     FLVGKKKEQHNRHQNPSNTACNLEPNIKQSSGGLRDIQTVVWVVKWYFCVNTLFELVD
                     KQYLTISEYELLNTSQLFLFKVRFALHIIANRREDRLIFQYQKSVAIILGYVDGDFLA
                     VETFMKDYYQTVTKVSRLNDILLQLLEDEILNTQYLNSRFMVSHGYIHSIDERIFIQI
                     PSTFIEIFLLIAKHNYVCGISAKTLRQMQTSINLIDCDYYKRRNNNRLFIELLQQNQG
                     VNKALKLMNRYGILERYIPAFGQIMGLMQYDLFHAYTVDQHTLFVIRNLRRFFVSEFA
                     KEFILCSEIAVGIQKPELLLLAGLFHDIAKGRGREHAQLGAIDVRKFCQYHQLKTNDI
                     DLVSQLVEKHLLMSMVAQKQDIGDFEVIKYFAEQVSTVEFLEFLYLLTVADIRATKDN
                     LWNSWKDSLLKKLFYNTKKYLENSNGQRPSVDQRVQDIKQTIINNSIIQGYPISEVEK
                     ILSTLPKDYYLRYDMSDVLWHLNFTTKITVDKIIVSSRISQYNVVDILILCNDFKGLF
                     FKLISILERLGLDIVDAKILTTKNNKVYNTISVLQDEALEHININQRIKNELDNLDVS
                     VRITHDIYMYQYFDHKVKVSFSLNEQWNLTQLEINALNKQGVLSNIAYVFSELNILLI
                     NARIATMGERVEDVFFISNAKNEPLSMAEKLILKESLEEKL"
     misc_feature    454218..456671
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /note="PII uridylyl-transferase; Provisional; Region:
                     glnD; PRK00275"
                     /db_xref="CDD:234709"
     misc_feature    454221..454652
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /note="Nucleotidyltransferase (NT) domain of Escherichia
                     coli adenylyltransferase (GlnE), Escherichia coli uridylyl
                     transferase (GlnD), and similar proteins; Region:
                     NT_GlnE_GlnD_like; cd05401"
                     /db_xref="CDD:143391"
     misc_feature    order(454422..454424,454428..454430,454506..454508)
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /note="metal binding triad; other site"
                     /db_xref="CDD:143391"
     misc_feature    454680..455078
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /note="GlnD PII-uridylyltransferase; Region:
                     GlnD_UR_UTase; pfam08335"
                     /db_xref="CDD:219800"
     misc_feature    455481..455939
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /note="Metal dependent phosphohydrolases with conserved
                     &apos;HD&apos; motif; Region: HDc; cd00077"
                     /db_xref="CDD:238032"
     misc_feature    order(455496..455498,455625..455630,455874..455876)
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    455628..455630
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    456210..>456347
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /note="ACT domains are commonly involved in specifically
                     binding an amino acid or other small ligand leading to
                     regulation of the enzyme; Region: ACT; cl09141"
                     /db_xref="CDD:245020"
     misc_feature    456507..456677
                     /gene="glnD"
                     /locus_tag="COSY_0438"
                     /note="C-terminal ACT domains of the bacterial
                     signal-transducing uridylyltransferase /uridylyl-removing
                     (UUR) enzyme, GlnD and related domains; Region:
                     ACT_ACR-UUR-like_2; cd04899"
                     /db_xref="CDD:153171"
     gene            456806..457132
                     /gene="trxA"
                     /locus_tag="COSY_0439"
                     /db_xref="GeneID:5172727"
     CDS             456806..457132
                     /gene="trxA"
                     /locus_tag="COSY_0439"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin 1"
                     /protein_id="YP_001219282.1"
                     /db_xref="GI:148244588"
                     /db_xref="GeneID:5172727"
                     /translation="MNDKIKIVVDASFEAEVVNSSQVVLVDFWAQWCGPCKTLMPVLD
                     KIADEYDGRVLIAKINIDENQKIPSKYGIRGIPTMLLFFEGVVQATKMGALSKAELSA
                     FIDANI"
     misc_feature    456836..457120
                     /gene="trxA"
                     /locus_tag="COSY_0439"
                     /note="TRX family; composed of two groups: Group I, which
                     includes proteins that exclusively encode a TRX domain;
                     and Group II, which are composed of fusion proteins of TRX
                     and additional domains. Group I TRX is a small ancient
                     protein that alter the redox...; Region: TRX_family;
                     cd02947"
                     /db_xref="CDD:239245"
     misc_feature    456866..457048
                     /gene="trxA"
                     /locus_tag="COSY_0439"
                     /note="Thioredoxin-like; Region: Thioredoxin_8; pfam13905"
                     /db_xref="CDD:222448"
     misc_feature    order(456902..456904,456911..456913)
                     /gene="trxA"
                     /locus_tag="COSY_0439"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239245"
     gene            457248..458510
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /db_xref="GeneID:5171835"
     CDS             457248..458510
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /note="An RNA-DNA helicase that actively releases nascent
                     mRNAs from paused transcription complexes"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="YP_001219283.1"
                     /db_xref="GI:148244589"
                     /db_xref="GeneID:5171835"
                     /translation="MKLSELKKFSPEKLLELAQSLGAENISRAKKQTLIFIILKAKAA
                     NDEEVLGDGVLDVLQDGYGFLRSSDDSYTSGADDIYISPNQIRRFNLSTGDLVAGKIR
                     APKKGEKYFALIKVSEVNSEDPDNVRNRIPFASLTPIHPNERINLEVGNGGTEDITAR
                     VIDLVAPFGKGQRGLLVAPPKAGKTMIMQNIATSISVNHPECELIVLLIDERPEEVTE
                     MARTVRGEVIASTFDEPAKRHVQVAEMVIQKTKRRSEQGKDVIILLDSITRLARAYNT
                     IAPSSGKVLTGGVDANALQRPKRFFGAARNIENGGSITIIATALIDTGSKMDEVIYQE
                     FKGTGNMELHLEKRLSEKRIFPAININASGTRREELITDEKELQKIWILRKILHPMDT
                     VEAAEFLINRLKLTKTNDEFFALMSQKK"
     misc_feature    457248..458501
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /note="transcription termination factor Rho; Provisional;
                     Region: rho; PRK09376"
                     /db_xref="CDD:236490"
     misc_feature    457260..457388
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /note="Rho termination factor, N-terminal domain; Region:
                     Rho_N; pfam07498"
                     /db_xref="CDD:203652"
     misc_feature    457398..457595
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /note="Rho_CSD: Rho protein cold-shock domain (CSD). Rho
                     protein is a transcription termination factor in most
                     bacteria. In bacteria, there are two distinct mechanisms
                     for mRNA transcription termination. In intrinsic
                     termination, RNA polymerase and nascent mRNA...; Region:
                     Rho_CSD; cd04459"
                     /db_xref="CDD:239906"
     misc_feature    order(457413..457415,457419..457421,457431..457433,
                     457437..457439,457443..457445,457479..457481,
                     457485..457487,457560..457562,457569..457577)
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:239906"
     misc_feature    457713..458459
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /note="Transcription termination factor rho is a bacterial
                     ATP-dependent RNA/DNA helicase. It is a homohexamer. Each
                     monomer consists of an N-terminal domain of the OB fold,
                     which is responsible for binding to cysteine rich
                     nucleotides. This alignment is of the...; Region:
                     rho_factor; cd01128"
                     /db_xref="CDD:238548"
     misc_feature    order(457764..457766,458097..458099,458130..458132,
                     458139..458144,458151..458153,458160..458162,
                     458169..458171,458244..458249,458253..458267,
                     458271..458273,458343..458348,458388..458390,
                     458400..458402)
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /note="multimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238548"
     misc_feature    457779..457802
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:238548"
     misc_feature    order(457788..457790,457794..457805,458310..458312)
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238548"
     misc_feature    458028..458042
                     /gene="rho"
                     /locus_tag="COSY_0440"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:238548"
     gene            458647..459720
                     /locus_tag="COSY_0441"
                     /db_xref="GeneID:5172611"
     CDS             458647..459720
                     /locus_tag="COSY_0441"
                     /note="Similar to permease, YjgP/YjgQ family."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219284.1"
                     /db_xref="GI:148244590"
                     /db_xref="GeneID:5172611"
                     /translation="MRNTLVILSAVFIVISLVVFGNQLVVVVKESLEEGIPVKDLLPL
                     VGFNMIRDIVPILSLSLLLAIILSINKLYKNSEAVIMNSLGLNNKHFMVFIQPLVIVI
                     VIVIVILTTVVVPWSKQQKDLIINHSKNISKFSFIKEREFQEFKNGDIIFFASKVSNF
                     NNSKEQNMEGIFIYTFINNEPVIILAKQAKKYTNLNTNSVYLRLKNGTNYHGFILDTK
                     KKILNFNLYDIQIIDGNMKKLISKVIKVESKSTFELFFSRKLTEIAEFQWRISQPLSI
                     LILSALGVLLGRTSQNGGRNLGVLIGVVVFILYNNALLISKSVLERGESLPIIGLWWV
                     HLVMLLLIFIFYSIRNRIFTNFF"
     misc_feature    458647..459684
                     /locus_tag="COSY_0441"
                     /note="Predicted permease YjgP/YjgQ family; Region:
                     YjgP_YjgQ; pfam03739"
                     /db_xref="CDD:217705"
     misc_feature    458665..459702
                     /locus_tag="COSY_0441"
                     /note="Predicted permeases [General function prediction
                     only]; Region: COG0795; cl12074"
                     /db_xref="CDD:245860"
     gene            459862..460260
                     /gene="folE"
                     /locus_tag="COSY_0442"
                     /db_xref="GeneID:5172539"
     CDS             459862..460260
                     /gene="folE"
                     /locus_tag="COSY_0442"
                     /EC_number="3.5.4.16"
                     /note="NADPH-dependent; catalyzes the reduction of
                     7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in
                     queuosine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine reductase"
                     /protein_id="YP_001219285.1"
                     /db_xref="GI:148244591"
                     /db_xref="GeneID:5172539"
                     /translation="MSSQPNKNLKVFDNPNIERNFIIQINMPEFTCLCPKTGQPDFAT
                     LYLEYIADKVCIELKSLKMYIWSYRSKGEFHEAVTNKILDDLIQISNPRFMRLKAIFN
                     VRGGIYTTIIAEYQQKNWTFKTKIDLQYQG"
     misc_feature    459880..460218
                     /gene="folE"
                     /locus_tag="COSY_0442"
                     /note="7-cyano-7-deazaguanine reductase; Provisional;
                     Region: PRK13258"
                     /db_xref="CDD:237320"
     gene            460269..461420
                     /gene="pcnB"
                     /locus_tag="COSY_0443"
                     /db_xref="GeneID:5172009"
     CDS             460269..461420
                     /gene="pcnB"
                     /locus_tag="COSY_0443"
                     /EC_number="2.7.7.19"
                     /codon_start=1
                     /transl_table=11
                     /product="poly(A) polymerase"
                     /protein_id="YP_001219286.1"
                     /db_xref="GI:148244592"
                     /db_xref="GeneID:5172009"
                     /translation="MKVIRQSVKFDRSLLDKDALKVINIINKAGFKAYLVGGCVRDFL
                     LSLTPKDFDIATNAKPEQVHKLFKRSRLIGRRFRLVHVMFSARKFIEVATFRSGKVQV
                     ANNGVVMRDNCYGNIEDDVVRRDLSINALYYDIETQEVIDYVGGLQDIRVQELHVIGN
                     PKKRFEQDPVRMIRVIRFQTKLDFHLSNEIKSAIFEQAPLLGNISTIRLYEECIKLFH
                     NEYGFKIYQRLEEYGLFKYLFKQTHKNEFIKKALLNTSDRIKRNQSVTPVFLFAVFLW
                     QAQNERFFVIKKKQCSTSLAMSQASEEVIIEQIKQVSLPRWLSSRIKDIWMIQPKLES
                     MNPKKVKELLKNPRFRMAYDFLLLRSISINPELAKVAKFWHKTQQLNQS"
     misc_feature    460299..461417
                     /gene="pcnB"
                     /locus_tag="COSY_0443"
                     /note="poly(A) polymerase; Region: pcnB; TIGR01942"
                     /db_xref="CDD:130997"
     misc_feature    460314..460721
                     /gene="pcnB"
                     /locus_tag="COSY_0443"
                     /note="Nucleotidyltransferase (NT) domain of ClassII
                     CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398"
                     /db_xref="CDD:143388"
     misc_feature    order(460377..460382,460389..460394,460419..460421,
                     460425..460427,460497..460499,460539..460541,
                     460554..460556,460635..460646,460653..460655)
                     /gene="pcnB"
                     /locus_tag="COSY_0443"
                     /note="active site"
                     /db_xref="CDD:143388"
     misc_feature    order(460377..460382,460389..460391,460419..460421,
                     460425..460427,460635..460643,460653..460655)
                     /gene="pcnB"
                     /locus_tag="COSY_0443"
                     /note="NTP binding site [chemical binding]; other site"
                     /db_xref="CDD:143388"
     misc_feature    order(460419..460421,460425..460427,460539..460541)
                     /gene="pcnB"
                     /locus_tag="COSY_0443"
                     /note="metal binding triad [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143388"
     misc_feature    460815..461000
                     /gene="pcnB"
                     /locus_tag="COSY_0443"
                     /note="Probable RNA and SrmB- binding site of polymerase
                     A; Region: PolyA_pol_RNAbd; pfam12627"
                     /db_xref="CDD:221674"
     misc_feature    461154..>461417
                     /gene="pcnB"
                     /locus_tag="COSY_0443"
                     /note="Polymerase A arginine-rich C-terminus; Region:
                     PolyA_pol_arg_C; pfam12626"
                     /db_xref="CDD:221673"
     gene            461790..462014
                     /gene="xseB"
                     /locus_tag="COSY_0444"
                     /db_xref="GeneID:5171875"
     CDS             461790..462014
                     /gene="xseB"
                     /locus_tag="COSY_0444"
                     /EC_number="3.1.11.6"
                     /note="catalyzes the bidirectional exonucleolytic cleavage
                     of DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="YP_001219287.1"
                     /db_xref="GI:148244593"
                     /db_xref="GeneID:5171875"
                     /translation="MSEKFNFNQGLIDLEKIVKAMESGDLSLEDSLNHFSKGVELTKQ
                     CQSALNKAEQKISMLTEQDNYTNEKPLKRL"
     misc_feature    461790..461981
                     /gene="xseB"
                     /locus_tag="COSY_0444"
                     /note="exodeoxyribonuclease VII small subunit;
                     Provisional; Region: PRK00977"
                     /db_xref="CDD:179195"
     gene            462064..462918
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /db_xref="GeneID:5171899"
     CDS             462064..462918
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /EC_number="2.5.1.10"
                     /codon_start=1
                     /transl_table=11
                     /product="geranyltranstransferase"
                     /protein_id="YP_001219288.1"
                     /db_xref="GI:148244594"
                     /db_xref="GeneID:5171899"
                     /translation="MDFNAYITRVNTKLEKYLPVQGYLTKAMRYSTLTNGKRFRPILT
                     YSVANIFSTHLDLVDSSSCAIEFIHAYSLIHDDLPAMDDDDIRHNQPTCHKLFGEAQA
                     ILVGDGLQTLAFKVLVNDNLIGSDTKIELIKSLTHASFEMAEGQAIDLSIIAKQVNIT
                     TLETMHRKKTGALLNCAVNLGAIVSKNCNNKDQTILNIFSKDIGLAYQIQDDVLDIET
                     PDELLGKKQYSDEYKNKPTYPSLLGLDKSRLVYKDLYEKAIDEIALLSVDAVELQQLT
                     IKLQERLF"
     misc_feature    462064..462855
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /note="Geranylgeranyl pyrophosphate synthase [Coenzyme
                     metabolism]; Region: IspA; COG0142"
                     /db_xref="CDD:223220"
     misc_feature    462133..462909
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /note="Trans-Isoprenyl Diphosphate Synthases,
                     head-to-tail; Region: Trans_IPPS_HT; cd00685"
                     /db_xref="CDD:173833"
     misc_feature    order(462265..462267,462274..462282,462286..462294,
                     462304..462309,462322..462327,462499..462501,
                     462508..462510,462568..462573,462580..462582,
                     462694..462699,462706..462708,462736..462738,
                     462751..462753,462766..462768)
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173833"
     misc_feature    order(462274..462297,462304..462309)
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /note="chain length determination region; other site"
                     /db_xref="CDD:173833"
     misc_feature    order(462289..462294,462307..462309,462322..462327,
                     462508..462510,462568..462570,462694..462699,
                     462706..462708,462736..462738,462751..462753,
                     462766..462768)
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /note="substrate-Mg2+ binding site; other site"
                     /db_xref="CDD:173833"
     misc_feature    order(462289..462294,462307..462309,462322..462327,
                     462568..462570,462694..462699)
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:173833"
     misc_feature    order(462289..462294,462307..462309,462322..462327,
                     462508..462510,462568..462570)
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /note="aspartate-rich region 1; other site"
                     /db_xref="CDD:173833"
     misc_feature    order(462313..462357,462715..462720,462736..462753,
                     462760..462774)
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /note="active site lid residues [active]"
                     /db_xref="CDD:173833"
     misc_feature    order(462694..462699,462706..462708,462736..462738,
                     462751..462753,462766..462768)
                     /gene="ispA"
                     /locus_tag="COSY_0445"
                     /note="aspartate-rich region 2; other site"
                     /db_xref="CDD:173833"
     gene            complement(462915..463859)
                     /gene="fabH"
                     /locus_tag="COSY_0446"
                     /db_xref="GeneID:5172698"
     CDS             complement(462915..463859)
                     /gene="fabH"
                     /locus_tag="COSY_0446"
                     /EC_number="2.3.1.41"
                     /note="acetylCoA ACP transacylase"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase III"
                     /protein_id="YP_001219289.1"
                     /db_xref="GI:148244595"
                     /db_xref="GeneID:5172698"
                     /translation="MSKFARIIGTGSYLPPTVITNDDLSKTINTTNEWIVARTGIKQR
                     HKVTNETTCDLAEKAANRALEMAGINVKDLDLIILATTTADKIFPATATILQTAIGAS
                     CPAFDLQSVCAGFIFALTTAEQYIKASAANKVLVVGSETLSRIVNWNDRSTAVLFGDG
                     AGAVVLSGSDNTGILYSKLFSDGNYLSSLQVSNNYINEVGFIEMSGNEVFKIAVNRLS
                     SLAEKTLKETNLNSNKLDWIVPHQANIRIISAVAKRIKTPMNKVIVTLENHGNTSAAS
                     IPLALDTAVRDGRIKRGDHLLFEGIGAGFSWGSILIQF"
     misc_feature    complement(462918..463853)
                     /gene="fabH"
                     /locus_tag="COSY_0446"
                     /note="3-oxoacyl-(acyl carrier protein) synthase III;
                     Reviewed; Region: PRK09352"
                     /db_xref="CDD:236475"
     misc_feature    complement(462924..463850)
                     /gene="fabH"
                     /locus_tag="COSY_0446"
                     /note="Ketoacyl-acyl carrier protein synthase III (KASIII)
                     initiates the elongation in type II fatty acid synthase
                     systems. It is found in bacteria and plants. Elongation of
                     fatty acids in the type II systems occurs by Claisen
                     condensation of malonyl-acyl...; Region: KAS_III; cd00830"
                     /db_xref="CDD:238426"
     misc_feature    complement(order(462948..462950,463287..463292,
                     463308..463325,463428..463430,463485..463490,
                     463497..463502,463509..463511,463533..463553,
                     463572..463574,463581..463583,463608..463610,
                     463614..463616))
                     /gene="fabH"
                     /locus_tag="COSY_0446"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238426"
     misc_feature    complement(order(463047..463049,463137..463139,
                     463524..463526))
                     /gene="fabH"
                     /locus_tag="COSY_0446"
                     /note="active site"
                     /db_xref="CDD:238426"
     misc_feature    complement(463128..463130)
                     /gene="fabH"
                     /locus_tag="COSY_0446"
                     /note="CoA binding pocket [chemical binding]; other site"
                     /db_xref="CDD:238426"
     gene            complement(463852..464871)
                     /gene="plsX"
                     /locus_tag="COSY_0447"
                     /db_xref="GeneID:5172499"
     CDS             complement(463852..464871)
                     /gene="plsX"
                     /locus_tag="COSY_0447"
                     /note="involved in acylation of glycerol-3-phosphate to
                     form 1-acyl-glycerol-3 phosphate for use in phospholipid
                     biosynthesis; functions with PlsY"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol-3-phosphate acyltransferase
                     PlsX"
                     /protein_id="YP_001219290.1"
                     /db_xref="GI:148244596"
                     /db_xref="GeneID:5172499"
                     /translation="MAIKVSIDASGGDYGIPVTIVAGIKALNIFQDLHLYFVGNEPSI
                     TTELGKYPSNTLNSRYTIIHASEVVLMNESPAIALRKKKDSSMRIAINLVKTFKADAC
                     VSAGNTGALMAISRFVLRTIKGIDRPAIMGRMPTITGHTHMLDLGANVDSKPKALVEF
                     ATMGSIAVKHTENIESPTIGLLNIGEEDMKGSEKIRKAATLLKASNLNYVGFVEGNDI
                     YKGIVDLIVCDGFEGNIALKASEGVASMMEHYLKQAFTRNLLTKLVSLIAIPVLKDFK
                     SSLNPDKYNGASLLGLRGIVVKSHGSANIDSFLTAITEAYIEAHAKISDKISLQISKE
                     LEHNE"
     misc_feature    complement(463873..464865)
                     /gene="plsX"
                     /locus_tag="COSY_0447"
                     /note="putative phosphate acyltransferase; Provisional;
                     Region: PRK05331"
                     /db_xref="CDD:235414"
     gene            complement(464877..465074)
                     /gene="rpmF"
                     /locus_tag="COSY_0448"
                     /db_xref="GeneID:5171830"
     CDS             complement(464877..465074)
                     /gene="rpmF"
                     /locus_tag="COSY_0448"
                     /note="some L32 proteins have zinc finger motifs
                     consisting of CXXC while others do not"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="YP_001219291.1"
                     /db_xref="GI:148244597"
                     /db_xref="GeneID:5171830"
                     /translation="MAVQKSRKTPSKRGMRRSHNALVKSTLSEDQETGEIHLRHHITT
                     DGFYHGKKIINKVQNIQKINA"
     misc_feature    complement(464925..465074)
                     /gene="rpmF"
                     /locus_tag="COSY_0448"
                     /note="50S ribosomal protein L32; Validated; Region: rpmF;
                     PRK01110"
                     /db_xref="CDD:234901"
     gene            complement(465098..465592)
                     /locus_tag="COSY_0449"
                     /db_xref="GeneID:5172086"
     CDS             complement(465098..465592)
                     /locus_tag="COSY_0449"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219292.1"
                     /db_xref="GI:148244598"
                     /db_xref="GeneID:5172086"
                     /translation="MQGIPDIIKLFSFAKKGLNFSHTYQVKDFPRIKKLLSNIDDKVK
                     VELSFYIKNNVVPCIKGSIQLSAIVDCQRCLNEVNIHLSPSFKLGFLKNEQQKEKLDS
                     SFETILNADKAFSTIEFITDELLISIPMSPMHPYKCQSYQDKEWINSQDKYHPFATLK
                     QLKD"
     misc_feature    complement(465104..465553)
                     /locus_tag="COSY_0449"
                     /note="Uncharacterized ACR, COG1399; Region: DUF177;
                     cl00616"
                     /db_xref="CDD:241985"
     gene            complement(465805..466506)
                     /gene="plsC"
                     /locus_tag="COSY_0450"
                     /db_xref="GeneID:5172540"
     CDS             complement(465805..466506)
                     /gene="plsC"
                     /locus_tag="COSY_0450"
                     /EC_number="2.3.1.51"
                     /note="phospholipid and glycerol acyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="YP_001219293.1"
                     /db_xref="GI:148244599"
                     /db_xref="GeneID:5172540"
                     /translation="MLFLRSLLYFLGSFIALIILVTVALSLFFLPFKFRYIILSKWSM
                     FCLWWLEYILNIKLQVIGKENIPPRPCVIVSNHQSTWETLGFQQIFPPQTWVLKKILL
                     WIPFFGWGLMLLKPIVINRGKKLKALKTIIKQGENRLKNGIFVVIFPEGTRQPYKKLG
                     KYQNGAIALAKKASCDIIPVYHNAGTIWPKGSFIKHAGTITVIIGKPIKIKEKSTKKL
                     TQIIRNWTQKQSKNF"
     misc_feature    complement(<465892..466479)
                     /gene="plsC"
                     /locus_tag="COSY_0450"
                     /note="1-acyl-sn-glycerol-3-phosphate acyltransferase
                     [Lipid metabolism]; Region: PlsC; COG0204"
                     /db_xref="CDD:223282"
     misc_feature    complement(465892..466353)
                     /gene="plsC"
                     /locus_tag="COSY_0450"
                     /note="Lysophospholipid Acyltransferases (LPLATs) of
                     Glycerophospholipid Biosynthesis: AGPAT-like; Region:
                     LPLAT_AGPAT-like; cd07989"
                     /db_xref="CDD:153251"
     misc_feature    complement(order(466048..466056,466207..466218,
                     466261..466263,466267..466269,466276..466278))
                     /gene="plsC"
                     /locus_tag="COSY_0450"
                     /note="putative acyl-acceptor binding pocket; other site"
                     /db_xref="CDD:153251"
     gene            467297..468049
                     /locus_tag="COSY_0451"
                     /db_xref="GeneID:5171831"
     CDS             467297..468049
                     /locus_tag="COSY_0451"
                     /note="short-chain dehydrogenase/reductase family"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="YP_001219294.1"
                     /db_xref="GI:148244600"
                     /db_xref="GeneID:5171831"
                     /translation="MEISTNYSITKGELKDRVILVTGANRGFGRAITLDLAKAGASVI
                     MLGRDLSSLENTYDEVINFGYQKPILYPLDLEGATPKHYEQLQKDILNNFEQLDGLIH
                     NASIIGTMMPIEQYDIKLWYSTMQININAPFMLTQVLIPVLNKSSDARVLFFSSSVGR
                     VAKAYWGAYGVSKFAIEGISKTLSEELERTNIKVNSLDPGRMRTKMRQIAYPAENIYN
                     NPLPETKSPVIVYLMSEKAKELNGKQITLFSI"
     misc_feature    467312..468031
                     /locus_tag="COSY_0451"
                     /note="putative oxoacyl-(acyl carrier protein) reductase;
                     Provisional; Region: PRK08945"
                     /db_xref="CDD:236357"
     misc_feature    467336..468025
                     /locus_tag="COSY_0451"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    order(467363..467365,467369..467374,467378..467380,
                     467435..467443,467603..467611,467756..467764,
                     467801..467803,467813..467815,467891..467902)
                     /locus_tag="COSY_0451"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    order(467678..467680,467762..467764,467801..467803,
                     467813..467815)
                     /locus_tag="COSY_0451"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            complement(468163..468966)
                     /gene="suhB"
                     /locus_tag="COSY_0452"
                     /db_xref="GeneID:5172427"
     CDS             complement(468163..468966)
                     /gene="suhB"
                     /locus_tag="COSY_0452"
                     /EC_number="3.1.3.25"
                     /note="extragenic suppressor protein SuhB"
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inositol-1(or 4)-monophosphatase"
                     /protein_id="YP_001219295.1"
                     /db_xref="GI:148244601"
                     /db_xref="GeneID:5172427"
                     /translation="MQHPTLNIAVKVARKAGNIILRYHNQINLLTIKNKTTNNFVSEV
                     NKAAKDAIINELKYTFPSHSILYEENSEILDNNRFQWIIDPLNGTTNYLHGFPQYSVS
                     IALYENKEPKHAVVYDPFKEELFTTSKGEGAYLNEQRIRITHTNGFENTLIGTGFSFK
                     ESKHLDTYLSMFKAIYLKVSGIRHTGSAALNLAYLAAGRLDGFWEIELNIWNIAAGVL
                     LVKEAGGFVGDFSGRDKYLKTGNVVAGNNQVFKAILKTIHPYLTVKLQR"
     misc_feature    complement(468196..468960)
                     /gene="suhB"
                     /locus_tag="COSY_0452"
                     /note="Archaeal fructose-1,6-bisphosphatase and related
                     enzymes of inositol monophosphatase family [Carbohydrate
                     transport and metabolism]; Region: SuhB; COG0483"
                     /db_xref="CDD:223559"
     misc_feature    complement(468229..468951)
                     /gene="suhB"
                     /locus_tag="COSY_0452"
                     /note="IMPase, inositol monophosphatase and related
                     domains. A family of Mg++ dependent phosphatases,
                     inhibited by lithium, many of which may act on inositol
                     monophosphate substrate. They dephosphorylate inositol
                     phosphate to generate inositol, which may be...; Region:
                     IMPase; cd01639"
                     /db_xref="CDD:238817"
     misc_feature    complement(order(468331..468336,468700..468717,
                     468760..468765,468832..468834,468850..468852,
                     468865..468867))
                     /gene="suhB"
                     /locus_tag="COSY_0452"
                     /note="active site"
                     /db_xref="CDD:238817"
     misc_feature    complement(order(468364..468375,468385..468387,
                     468409..468429,468442..468444,468451..468453,
                     468460..468462,468469..468474,468496..468501,
                     468505..468507,468511..468519,468673..468690,
                     468694..468699,468847..468849,468853..468855))
                     /gene="suhB"
                     /locus_tag="COSY_0452"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238817"
     gene            468980..469723
                     /locus_tag="COSY_0453"
                     /db_xref="GeneID:5172127"
     CDS             468980..469723
                     /locus_tag="COSY_0453"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="YP_001219296.1"
                     /db_xref="GI:148244602"
                     /db_xref="GeneID:5172127"
                     /translation="MKKGINYTFDKVRVVMVNTTEPGNIGAAARAMKNMNLSKLYLVN
                     PKGYPSATATARASGADDVLSDAIVCESLEEALKGTHLVIGASARQRNIKWRQMDVVG
                     TCNKIQKTITIDSQEVAVIFGTEKSGLTNKELDLCQILMTIPGNPDYFSLNVASAIQV
                     FAYQNYIYNTPTEFKENVSKLASFDELESFYTHLTQVLEHIEYFKDQHSQTLLMRRLR
                     CFFTKVEPKIEEVSIFRGILKNIKPFKRL"
     misc_feature    469001..469705
                     /locus_tag="COSY_0453"
                     /note="rRNA methylase [Translation, ribosomal structure
                     and biogenesis]; Region: LasT; COG0565"
                     /db_xref="CDD:223639"
     misc_feature    469010..469468
                     /locus_tag="COSY_0453"
                     /note="SpoU rRNA Methylase family; Region: SpoU_methylase;
                     pfam00588"
                     /db_xref="CDD:216010"
     gene            complement(469761..471611)
                     /gene="htpG"
                     /locus_tag="COSY_0454"
                     /db_xref="GeneID:5172545"
     CDS             complement(469761..471611)
                     /gene="htpG"
                     /locus_tag="COSY_0454"
                     /note="molecular chaperone"
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein 90"
                     /protein_id="YP_001219297.1"
                     /db_xref="GI:148244603"
                     /db_xref="GeneID:5172545"
                     /translation="MTIKQTHSFQTEVSQLLHLMIHSLYSNKEIFLRELISNASDAVD
                     KLKFKSLSDDTLIEGKEALQIHIDVNKDANTITITDNGIGMSEVEVNKNIGTIANSGT
                     KKFLKSLNETQAQDSNLIGQFGVGFYSSFIVSDKVEIITRKAGSKSKKGTKWASTGKG
                     KYSIESIDRPDFGTSVILHIKKDEKEFLDDYRLRNIISKYSDHITVPIMMVKVSEDNK
                     DIEYERINKANAFWAQDKQDLKQKDYDEFYKSLTYDLEAPLTQLHNRVEGNIDYTSLL
                     FIPSKSPFDIWEPKRKGGIKLYAKRVFIMEDNEALMPLYLRFVKGVIDTADLSLNLSR
                     EILQDNKVIKAIRKASVKRILSVLEKMAKNKPEDYATFWQEFGMLMKEGVVEDTINKD
                     KIAKLLRFTTNKSKNATQTVTLEHYIKNIQKDQKAIYYITAETYETAKGSPHLENFNQ
                     KNIEVLLLSDRVDEWMVSNFREFDGIQLKSIAKGNLEDFDSKEEKKAKEEVAKNFEIV
                     IEKMQKILDSQVKEIKISSRLSESPSCLVADENEMGGNMERIMKSLGQDIPDTKPILE
                     INPTHSLVKKLKTKIDEDLVKVLFDQAVLSEGGQLKDPAEFVKRINKLIN"
     misc_feature    complement(469767..471608)
                     /gene="htpG"
                     /locus_tag="COSY_0454"
                     /note="heat shock protein 90; Provisional; Region:
                     PRK05218"
                     /db_xref="CDD:235366"
     misc_feature    complement(471153..471527)
                     /gene="htpG"
                     /locus_tag="COSY_0454"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(471156..471161,471174..471176,
                     471195..471197,471231..471242,471357..471362,
                     471366..471368,471372..471374,471378..471380,
                     471489..471491,471498..471500,471510..471512))
                     /gene="htpG"
                     /locus_tag="COSY_0454"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(471498..471500)
                     /gene="htpG"
                     /locus_tag="COSY_0454"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(471234..471236,471240..471242,
                     471360..471362,471366..471368))
                     /gene="htpG"
                     /locus_tag="COSY_0454"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(<470382..>470630)
                     /gene="htpG"
                     /locus_tag="COSY_0454"
                     /note="Phage maturation protein; Region: Phage_mat-A;
                     cl17797"
                     /db_xref="CDD:248351"
     gene            472193..472729
                     /locus_tag="COSY_0455"
                     /db_xref="GeneID:5172628"
     CDS             472193..472729
                     /locus_tag="COSY_0455"
                     /note="putative translation factor, Sua5/YciO/YrdC/YwlC
                     family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219298.1"
                     /db_xref="GI:148244604"
                     /db_xref="GeneID:5172628"
                     /translation="MNFHTRFAASCLKVGGVISNPTDTIQGLTCLPKFESSMTRILQF
                     KHRSSTKGLILLASDVYYFKDYVKDISLLINVTINTQPTTYLLKANRRTSQLLTGDFD
                     TIALRLTNNQLITNLCTATHSALVSSSANITSKCNARSMLDLKLFFSDKLDFIIPPKT
                     YNTQASKIINLQTGEKIR"
     misc_feature    472226..>472591
                     /locus_tag="COSY_0455"
                     /note="Telomere recombination; Region: Sua5_yciO_yrdC;
                     cl00305"
                     /db_xref="CDD:241768"
     gene            472726..473652
                     /gene="hemF"
                     /locus_tag="COSY_0456"
                     /db_xref="GeneID:5172541"
     CDS             472726..473652
                     /gene="hemF"
                     /locus_tag="COSY_0456"
                     /EC_number="1.3.3.3"
                     /note="catalyzes the conversion of the propionic acid
                     groups of rings I and III to vinyl groups during heme
                     synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="YP_001219299.1"
                     /db_xref="GI:148244605"
                     /db_xref="GeneID:5172541"
                     /translation="MIEKLQKYLLMLQSDICEQFEQLDGKVKFIKDAWKKPNNTGNGL
                     TRILVNGAVFEQAGVNFSIIRSNDMPASATELRPELAGRSFTALGVSLVIHPHNPYVP
                     TSHANVRFFIAKKKGKIPIWWFGGGFDLTPYYGFDEDAIFWHQSAKQACDLFGKDVYL
                     KYKKWCDDYFYLKHRNEQRGIGGLFFDDLNEGGFDKCFAFMRSVGDGYIKAYQPIVER
                     RKDTSYTDHERQFQLYRRGRYVEFNLVYDRGTLFGLQTGGRTESILMSIPPLVRWQYQ
                     YQPEPGSQEERLYTRFIQPQDWINISFKQNEI"
     misc_feature    472729..473622
                     /gene="hemF"
                     /locus_tag="COSY_0456"
                     /note="coproporphyrinogen III oxidase; Provisional;
                     Region: PRK05330"
                     /db_xref="CDD:235413"
     misc_feature    472732..473622
                     /gene="hemF"
                     /locus_tag="COSY_0456"
                     /note="Coproporphyrinogen III oxidase; Region:
                     Coprogen_oxidas; pfam01218"
                     /db_xref="CDD:216370"
     gene            473642..473866
                     /locus_tag="COSY_0457"
                     /db_xref="GeneID:5172476"
     CDS             473642..473866
                     /locus_tag="COSY_0457"
                     /note="Similar to molybdopterin biosynthesis MoeB
                     protein-related protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219300.1"
                     /db_xref="GI:148244606"
                     /db_xref="GeneID:5172476"
                     /translation="MKYNLNVKHLFCPMSVIRLSEMIKKIKINDTIEILTTDTGVLHD
                     ISAWCKVHGHQVILVNQKTNEIIIFVEKTG"
     misc_feature    473654..473857
                     /locus_tag="COSY_0457"
                     /note="SirA, YedF, and YeeD. Two-layered alpha/beta
                     sandwich domain.  SirA (also known as UvrY,  and YhhP)
                     belongs to a family of bacterial two-component response
                     regulators that controls secondary metabolism and
                     virulence. The other member of this...; Region:
                     SirA_YedF_YeeD; cd00291"
                     /db_xref="CDD:238180"
     misc_feature    order(473654..473659,473666..473668,473675..473686,
                     473690..473692)
                     /locus_tag="COSY_0457"
                     /note="CPxP  motif; other site"
                     /db_xref="CDD:238180"
     gene            473999..475414
                     /gene="glnA"
                     /locus_tag="COSY_0458"
                     /db_xref="GeneID:5172192"
     CDS             473999..475414
                     /gene="glnA"
                     /locus_tag="COSY_0458"
                     /EC_number="6.3.1.2"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="YP_001219301.1"
                     /db_xref="GI:148244607"
                     /db_xref="GeneID:5172192"
                     /translation="MSAKNIMKIIEDNKVKFIDFRFTDTIGKEQHVSVPAHTMNIAKL
                     TEGQTFDGSSIAGWKSIDKSDMIMMPDTATAVMDPFTEESTLNIICDIIESNNMANYE
                     KDPRSIAKRAEIYLNKTGIGDTAYFGNEPEFFIFDSVKWDTGFGLGKAFYEINSEEAY
                     WESGSDFEGGNKGHRPRIKGGYFPVPPVDSLHNLRAQMCLAIEEMGVTTEIHHHEVGT
                     AGQCEIGALFNTLVKKADETQILKYCVHNVAHSYGKTATFMPKPIAVDNGNGMHVHQS
                     ITKNGKNLFDGNEYGNLSEMALHYIGGIIKHAQALNAFTNASTNSYKRLVPGFEAPEM
                     LAYSAKNRSAAIRIPFVSHSKGRRIEVRFPDSTANPYLAFAAMLMAGLDGIKNKIHPG
                     KPGDEDLYSLTEKEKLSFPKVCSSLDQALEALDKDREFLKKGSVFTDNIIDSFINLKI
                     KEVTALRASPHPVEFDMYYSV"
     misc_feature    473999..475411
                     /gene="glnA"
                     /locus_tag="COSY_0458"
                     /note="glutamine synthetase; Provisional; Region: glnA;
                     PRK09469"
                     /db_xref="CDD:181884"
     misc_feature    474038..474280
                     /gene="glnA"
                     /locus_tag="COSY_0458"
                     /note="Glutamine synthetase, beta-Grasp domain; Region:
                     Gln-synt_N; pfam03951"
                     /db_xref="CDD:217811"
     misc_feature    474302..475141
                     /gene="glnA"
                     /locus_tag="COSY_0458"
                     /note="Glutamine synthetase, catalytic domain; Region:
                     Gln-synt_C; pfam00120"
                     /db_xref="CDD:215731"
     gene            475512..476480
                     /gene="bioB"
                     /locus_tag="COSY_0459"
                     /db_xref="GeneID:5172706"
     CDS             475512..476480
                     /gene="bioB"
                     /locus_tag="COSY_0459"
                     /EC_number="2.8.1.6"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthetase"
                     /protein_id="YP_001219302.1"
                     /db_xref="GI:148244608"
                     /db_xref="GeneID:5172706"
                     /translation="MTQQRHNWTLKEVEALFTLPFNDLLFQAHSIHRKNFDPNQVQIS
                     SLLNIKTGACPEDCLYCSQSSKYDTGLEREKLMEIDLVLKQAKQAQDNGATRFCMGAA
                     WRNPTDKSINKVIPMIQGVKDMGMETCVTLGMLTQKQAFVLKEVGLDYYNHNIDTSKE
                     NYSNIVTTRNFQDRLNTLESVQNANIRVCSGGILGLGEDQTDRASMLRSLSNLAIHPD
                     SVPLNLLVPIPGTPFENIEPPTESEFIRTIAVARIMMPKSVVRLSAGRTKMGDTMQAL
                     CFFAGANSIFYGEQLLTTDNPNTDSDQDLFVRLGINQKQANNLQSV"
     misc_feature    475551..476441
                     /gene="bioB"
                     /locus_tag="COSY_0459"
                     /note="biotin synthase; Region: bioB; TIGR00433"
                     /db_xref="CDD:232973"
     misc_feature    475662..476261
                     /gene="bioB"
                     /locus_tag="COSY_0459"
                     /note="Radical SAM superfamily. Enzymes of this family
                     generate radicals by combining a 4Fe-4S cluster and
                     S-adenosylmethionine (SAM) in close proximity. They are
                     characterized by a conserved CxxxCxxC motif, which
                     coordinates the conserved iron-sulfur cluster; Region:
                     Radical_SAM; cd01335"
                     /db_xref="CDD:100105"
     misc_feature    order(475671..475673,475677..475679,475683..475685,
                     475689..475697,475803..475805,475809..475814,
                     475896..475904,475971..475973,476088..476090,
                     476181..476186)
                     /gene="bioB"
                     /locus_tag="COSY_0459"
                     /note="FeS/SAM binding site; other site"
                     /db_xref="CDD:100105"
     misc_feature    476172..476447
                     /gene="bioB"
                     /locus_tag="COSY_0459"
                     /note="Biotin and Thiamin Synthesis associated domain;
                     Region: BATS; smart00876"
                     /db_xref="CDD:214877"
     gene            complement(476443..477465)
                     /gene="murG"
                     /locus_tag="COSY_0460"
                     /db_xref="GeneID:5172424"
     CDS             complement(476443..477465)
                     /gene="murG"
                     /locus_tag="COSY_0460"
                     /EC_number="2.4.1.227"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="YP_001219303.1"
                     /db_xref="GI:148244609"
                     /db_xref="GeneID:5172424"
                     /translation="MFNTAKKILIMAGGTGGHIFPALAIANELKKHSSNIQWLGSNLG
                     MENNIIPKHNIKLHTVSSVGLRGKNVISLIKAPFLLSYATLQVIKIFLKFKPDVVLGM
                     GGFTSGIGGLVAWVFKTTLVIHEQNSIPGTTNKILNKIATKTFQAFDDTFIRNATTSG
                     NPIVFNPIEKQNNNKLNLLIIGGSLGSKPINEIVTQLNIDINIWHQTGKLHADTVKSQ
                     YKNSAVKVTAFITEMASAYAWADIVLCRAGAMTVSELMLSATSSILIPLPNSIDNHQF
                     HNAKILSDNNAGILIEQKDLTIELLEGILLNINKNQIKQMSSNALKIAKPNAVKQIVD
                     YLLVSD"
     misc_feature    complement(476464..477450)
                     /gene="murG"
                     /locus_tag="COSY_0460"
                     /note="undecaprenyldiphospho-muramoylpentapeptide beta-N-
                     acetylglucosaminyltransferase; Provisional; Region: murG;
                     PRK00726"
                     /db_xref="CDD:234825"
     misc_feature    complement(476464..477447)
                     /gene="murG"
                     /locus_tag="COSY_0460"
                     /note="MurG is an N-acetylglucosaminyltransferase, the
                     last enzyme involved in the intracellular phase of
                     peptidoglycan biosynthesis. It transfers
                     N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4
                     hydroxyl of a lipid-linked N-acetylmuramoyl
                     pentapeptide...; Region: GT1_MurG; cd03785"
                     /db_xref="CDD:99961"
     misc_feature    complement(order(476632..476634,476641..476646,
                     476665..476667,476704..476706,476713..476724,
                     476767..476769,476779..476781,476848..476850,
                     476914..476916,477085..477087,477415..477417))
                     /gene="murG"
                     /locus_tag="COSY_0460"
                     /note="active site"
                     /db_xref="CDD:99961"
     misc_feature    complement(order(477043..477045,477118..477120,
                     477202..477204,477235..477237,477244..477246))
                     /gene="murG"
                     /locus_tag="COSY_0460"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99961"
     gene            478303..479916
                     /locus_tag="COSY_0461"
                     /db_xref="GeneID:5172311"
     CDS             478303..479916
                     /locus_tag="COSY_0461"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="YP_001219304.1"
                     /db_xref="GI:148244610"
                     /db_xref="GeneID:5172311"
                     /translation="MISTANITMQFGEKPLFENISIKFQDGNRYGLIGANGCGKSTFM
                     RILTGELIPTNGTVHISDGERLGILRQDQFSFENFSVIDTVIMGHHELWIIKKERDRI
                     YALPEMSEEDGIKVAELEMKFAEMDGYMAESSASELLLGLDFPEEQHYGSMNKIAPGW
                     KLRILLAQALFSDPDILLLDEPTNNLDINSIRWLEDVLRERKATMIIISHDRHFLNGV
                     CTHMSDLDYGALNTFPGNYDHFMIASTAIQEKMQADNAKKEVKIKTLKHFVSRFSANA
                     SKSKQATSRLKQLDKITLDDIKPSSRVSPYIIFNQEKKIHRNILEVEDLSKSFNPKED
                     TEKDGKFEVLKSINFLFEAGDRIAVIGQNGIGKTTLLRTLVGEIKPDRGKIKWSENIN
                     IGYYAQDHSKDFEIDMSVLDWMCQFKSEKDDIQAMRAVLGKMLFGKENIGKSVTSLSG
                     GEKGRMLFGKLMLQKPNILVMDEPTNHLDIESIEALNLALDNYKGSLIFVSHDREFVS
                     SLSTKVLELKEDGMHYYSGNYEDYLVSKK"
     misc_feature    478303..479910
                     /locus_tag="COSY_0461"
                     /note="ABC transporter ATP-binding protein; Provisional;
                     Region: PRK15064"
                     /db_xref="CDD:237894"
     misc_feature    478336..478974
                     /locus_tag="COSY_0461"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    478402..478425
                     /locus_tag="COSY_0461"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(478411..478416,478420..478428,478513..478515,
                     478840..478845,478930..478932)
                     /locus_tag="COSY_0461"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    478504..478515
                     /locus_tag="COSY_0461"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(478711..478719,478777..478797)
                     /locus_tag="COSY_0461"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    478828..478845
                     /locus_tag="COSY_0461"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    478852..478863
                     /locus_tag="COSY_0461"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    478918..478938
                     /locus_tag="COSY_0461"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     misc_feature    478972..479229
                     /locus_tag="COSY_0461"
                     /note="ABC transporter; Region: ABC_tran_2; pfam12848"
                     /db_xref="CDD:221805"
     misc_feature    479260..479865
                     /locus_tag="COSY_0461"
                     /note="ATP-binding cassette domain of elongation factor 3,
                     subfamily F; Region: ABCF_EF-3; cd03221"
                     /db_xref="CDD:213188"
     gene            480049..480654
                     /locus_tag="COSY_0462"
                     /db_xref="GeneID:5172723"
     CDS             480049..480654
                     /locus_tag="COSY_0462"
                     /EC_number="2.5.1.9"
                     /note="catalyzes the formation of riboflavin from
                     6,7-dimethyl-8-(1-D-ribityl)lumazine"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase subunit alpha"
                     /protein_id="YP_001219305.1"
                     /db_xref="GI:148244611"
                     /db_xref="GeneID:5172723"
                     /translation="MFTGIIQAIGKIKSIELGSFCFQAKKSFFDEVKIGDSIAVNGVC
                     LTTIKIDDNYFKVDISKETLRCTIFSHLGVDSLVNLEKTLRLNQGIDGHLVSGHVDGI
                     VKVVGRSIEGKSIRFKMKTPKNLIKYITKKGSICINGVSLTVNNINDCVLDINIVPYT
                     LKTTTLGELEINSKANLEVDIIARHIERLLYFEKNSYEIYH"
     misc_feature    480049..480615
                     /locus_tag="COSY_0462"
                     /note="riboflavin synthase subunit alpha; Provisional;
                     Region: PRK09289"
                     /db_xref="CDD:236455"
     misc_feature    480055..480294
                     /locus_tag="COSY_0462"
                     /note="Lumazine binding domain; Region: Lum_binding;
                     pfam00677"
                     /db_xref="CDD:201387"
     misc_feature    480334..480588
                     /locus_tag="COSY_0462"
                     /note="Lumazine binding domain; Region: Lum_binding;
                     pfam00677"
                     /db_xref="CDD:201387"
     gene            480638..481711
                     /gene="ribAB"
                     /locus_tag="COSY_0463"
                     /db_xref="GeneID:5172674"
     CDS             480638..481711
                     /gene="ribAB"
                     /locus_tag="COSY_0463"
                     /EC_number="3.5.4.25"
                     /note="bifunctional enzyme,
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin biosynthesis protein
                     RibBA"
                     /protein_id="YP_001219306.1"
                     /db_xref="GI:148244612"
                     /db_xref="GeneID:5172674"
                     /translation="MKSTIKEILKDYSQGKMIILMDDEDRENEGDLIIPAETVTKEDI
                     NFMATHGRGLICLTLTQERCKQLNLPLMVAQNNDSNGTNFTVSIEAIKGVTTGISAAD
                     RAKTILDAVAKDAKPDDIVQPGHIFPLMAQPGGVLIRAGHTEAGCDLARLAGFEPASV
                     IVEILNKDGSMARRDDLEIFAKKHDIKLGTIENLISYRVENEKTIERINEREFKTEFA
                     TFRLISFLDSIHNETHLALVKGEINSNADTYVRVHMEDTFKDVLREKLNSFSVDAVLK
                     CIAKSDSGVLLLLRMQTNQSILENIDNVNCDIHDDIKTYGVGAQILSDLGVKRMKILG
                     NPRKLYGLKGFGLEVTEYVDTNK"
     misc_feature    480644..481699
                     /gene="ribAB"
                     /locus_tag="COSY_0463"
                     /note="bifunctional 3,4-dihydroxy-2-butanone 4-phosphate
                     synthase/GTP cyclohydrolase II-like protein; Provisional;
                     Region: PRK14019"
                     /db_xref="CDD:237587"
     misc_feature    480650..481231
                     /gene="ribAB"
                     /locus_tag="COSY_0463"
                     /note="3,4-dihydroxy-2-butanone 4-phosphate synthase;
                     Region: DHBP_synthase; pfam00926"
                     /db_xref="CDD:216197"
     misc_feature    481250..481696
                     /gene="ribAB"
                     /locus_tag="COSY_0463"
                     /note="GTP cyclohydrolase II; Region: GTP_cyclohydro2;
                     pfam00925"
                     /db_xref="CDD:216196"
     misc_feature    order(481259..481279,481301..481303,481307..481315,
                     481334..481336,481340..481342,481346..481348,
                     481400..481402,481406..481411,481415..481423,
                     481433..481435,481451..481453,481460..481462,
                     481499..481501,481505..481507,481529..481534)
                     /gene="ribAB"
                     /locus_tag="COSY_0463"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238348"
     misc_feature    order(481388..481405,481409..481411,481430..481432,
                     481511..481522,481544..481546,481568..481570,
                     481574..481576,481637..481642,481649..481651)
                     /gene="ribAB"
                     /locus_tag="COSY_0463"
                     /note="active site"
                     /db_xref="CDD:238348"
     gene            481722..482225
                     /gene="ribH"
                     /locus_tag="COSY_0464"
                     /db_xref="GeneID:5172627"
     CDS             481722..482225
                     /gene="ribH"
                     /locus_tag="COSY_0464"
                     /EC_number="2.5.1.9"
                     /note="6,7-dimethyl-8-ribityllumazine synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase beta chain"
                     /protein_id="YP_001219307.1"
                     /db_xref="GI:148244613"
                     /db_xref="GeneID:5172627"
                     /translation="MEFKFNKDGSRDFLSKKKIAIIVGYFYQDICDNLLLASQETLTK
                     YGIKANNINVFYAPGAFEIPLLAKKLASQQINGKNLYNGIVALGAVINGETPHFKFIC
                     NECARGVSNVSYQYEIPTTFGVITTNNMEQTIARAGGYKGNKGEEATMAMIIMLYLMQ
                     QADTQFF"
     misc_feature    481776..482189
                     /gene="ribH"
                     /locus_tag="COSY_0464"
                     /note="lumazine synthase (6,7-dimethyl-8-ribityllumazine
                     synthase, LS), catalyzes the penultimate step in the
                     biosynthesis of riboflavin (vitamin B2); type-I; Region:
                     Lumazine_synthase-I; cd09209"
                     /db_xref="CDD:187742"
     misc_feature    order(481779..481781,481797..481799,481884..481895,
                     481902..481907,481911..481919,481923..481931,
                     481935..481937,481962..481964,481995..481997,
                     482001..482006,482010..482012,482016..482021,
                     482025..482033,482037..482045,482049..482063,
                     482070..482075,482085..482087,482091..482093,
                     482097..482099,482103..482105,482115..482117,
                     482127..482129,482151..482153,482160..482162,
                     482172..482174,482181..482186)
                     /gene="ribH"
                     /locus_tag="COSY_0464"
                     /note="homopentamer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187742"
     misc_feature    order(481797..481802,481896..481907,481983..482000,
                     482004..482006,482010..482015,482082..482096,
                     482127..482129,482151..482153,482160..482162)
                     /gene="ribH"
                     /locus_tag="COSY_0464"
                     /note="active site"
                     /db_xref="CDD:187742"
     gene            482228..482653
                     /gene="nusB"
                     /locus_tag="COSY_0465"
                     /db_xref="GeneID:5172444"
     CDS             482228..482653
                     /gene="nusB"
                     /locus_tag="COSY_0465"
                     /note="transcription termination factor NusB"
                     /codon_start=1
                     /transl_table=11
                     /product="N utilization substance protein B"
                     /protein_id="YP_001219308.1"
                     /db_xref="GI:148244614"
                     /db_xref="GeneID:5172444"
                     /translation="MSFKTPKQRTRERVIQALYQYLVSGGEVFQIEQQFLNQKQGKIS
                     KVFFSDLFINILENRFVLDELITSTISRGTEELGSVEHSILYLGTFELKFNSEVPYKV
                     VINESLALAKLYGAEGSYKLINVSLDKLARILRKIELIN"
     misc_feature    482243..482641
                     /gene="nusB"
                     /locus_tag="COSY_0465"
                     /note="transcription antitermination protein NusB;
                     Reviewed; Region: nusB; PRK00202"
                     /db_xref="CDD:234686"
     misc_feature    482252..482260
                     /gene="nusB"
                     /locus_tag="COSY_0465"
                     /note="putative RNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238253"
     gene            complement(482789..486469)
                     /gene="metH"
                     /locus_tag="COSY_0466"
                     /db_xref="GeneID:5171910"
     CDS             complement(482789..486469)
                     /gene="metH"
                     /locus_tag="COSY_0466"
                     /EC_number="2.1.1.13"
                     /note="cobalamin-dependent methionine synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydrofolate--homocysteine
                     methyltransferase"
                     /protein_id="YP_001219309.1"
                     /db_xref="GI:148244615"
                     /db_xref="GeneID:5171910"
                     /translation="MLYTCIMLIMNIKQILKSLLNKRILVLDGAMGTMIQQHKLTEQE
                     YRGDRFKDWHVLVQGNNDLLSLTQPQIIKNIHKDYLKVGADIIETNTFNATRTSMSDY
                     KMEKLAYEINLKSAKIARQAADEFSNTKKPRFVAGVIGPTSRTCSLSPDVNDPGFRNI
                     TFDELVDVYIESTRGLIKGGVDIILIETIFDTLNAKAAIFAIEQVFEDDGIELPIMIS
                     GTITDASGRTLSGQMTEAFYNSLRHAKPISIGLNCALGPDLLRQYVAEMSRVADTYVS
                     AHPNAGLPNEFGEYDLNALTMSEQVSEWARSGLVNILGGCCGSTPDHIRAIADSINRI
                     PPRKIPTIKPECRLSALEAFNIGNDSLFVNIGERANITGSAKFKRLILNQEYEKALDI
                     CRTQVEEGAQMIDINMDEGMLDGKTAMIRFINLIASEPDIAKVPLIVDSSKWEIIEAG
                     LKCTQGKPIVNSISLKEGKTKFIQYARLCKRYGAAIIVMAFDESGQADTQARKIEICT
                     KAYYILVNNVNFPPEDIIFDPNIFAIATGIEEHNNYGIDFIEATRAIKKNLPYAKISG
                     GVSNVSFSFRGNNTVREAIHSVFLYHTVKAGMTMGIVNAGQLMVYNDIDPELKKAVED
                     VVLNINKQAGERLVDIALKFSNTFEQKNNKQNLEWRTWAVERRLEHALVKGITTYINK
                     DTQEAFDKLGRPILVIEGPLMSGMNVVGDLFSAGKMFLPQVVKSARVMKKSVAYLDPF
                     LENEKENCVTSSQGKILMATVKGDVHDIGKNIVSVVLSCNNYKIIDLGVMVPTETILE
                     TARKENVDIIGLSGLITPSLDEMVFVAKEMTRQGLKLPLMIGGATTSKAHTAVKIEPE
                     YDHGVFYVKDASKSVGVATALLSKTLKQQLLIDTKIDYENVRKRRINKGKSKLISLEK
                     ARANRPNISFNSIVKPKKLGIHVFKNYNLAEIFEFIDWVPFFQTWELTGKFPDILTDE
                     IVGESASILFNDAKVLFKKVINERLLTANAVIGIFPANSINEDIELYDENNEVIITLN
                     HLRQQLDKKGNTPNFCLSDFIASKDSGINDYMGAFAVTTGINIELLITTFKADHDDYN
                     SIMIKAIADRLVEGFTELMHFKLRTKLWGYSFERFDNNQFIQEKFDGIRPAPGYPSCP
                     EHSEKEKLWTLLDVKNNTGMILTSSYAMLPTASVSGWYFANPDARYFGVAKINQSQLN
                     NYAKRKNISLEQAEKLLSPNLE"
     misc_feature    complement(482795..486451)
                     /gene="metH"
                     /locus_tag="COSY_0466"
                     /note="B12-dependent methionine synthase; Provisional;
                     Region: metH; PRK09490"
                     /db_xref="CDD:236539"
     misc_feature    complement(485480..486445)
                     /gene="metH"
                     /locus_tag="COSY_0466"
                     /note="Methionine synthase I (cobalamin-dependent),
                     methyltransferase domain [Amino acid transport and
                     metabolism]; Region: MetH; COG0646"
                     /db_xref="CDD:223719"
     misc_feature    complement(484616..485386)
                     /gene="metH"
                     /locus_tag="COSY_0466"
                     /note="MeTr subgroup of pterin binding enzymes. This
                     family includes cobalamin-dependent methyltransferases
                     such as methyltetrahydrofolate, corrinoid iron-sulfur
                     protein methyltransferase (MeTr) and methionine synthase
                     (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740"
                     /db_xref="CDD:238381"
     misc_feature    complement(order(484658..484660,484664..484666,
                     484757..484759,484769..484771,484886..484888,
                     485003..485005,485081..485083,485087..485089,
                     485150..485152,485360..485362))
                     /gene="metH"
                     /locus_tag="COSY_0466"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238381"
     misc_feature    complement(483836..484480)
                     /gene="metH"
                     /locus_tag="COSY_0466"
                     /note="B12 binding domain of methionine synthase. This
                     domain binds methylcobalamin, which it uses as an
                     intermediate methyl carrier from methyltetrahydrofolate
                     (CH3H4folate) to homocysteine (Hcy); Region:
                     methionine_synthase_B12_BD; cd02069"
                     /db_xref="CDD:239020"
     misc_feature    complement(order(483860..483862,483869..483871,
                     483878..483880,483944..483946,484025..484033,
                     484037..484045,484154..484156,484163..484183,
                     484301..484303,484310..484312,484361..484363,
                     484373..484375))
                     /gene="metH"
                     /locus_tag="COSY_0466"
                     /note="B12 binding site [chemical binding]; other site"
                     /db_xref="CDD:239020"
     misc_feature    complement(484172..484174)
                     /gene="metH"
                     /locus_tag="COSY_0466"
                     /note="cobalt ligand [ion binding]; other site"
                     /db_xref="CDD:239020"
     misc_feature    complement(482885..483292)
                     /gene="metH"
                     /locus_tag="COSY_0466"
                     /note="Vitamin B12 dependent methionine synthase,
                     activation domain; Region: Met_synt_B12; pfam02965"
                     /db_xref="CDD:111813"
     gene            486758..487144
                     /locus_tag="COSY_0467"
                     /db_xref="GeneID:5172091"
     CDS             486758..487144
                     /locus_tag="COSY_0467"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219310.1"
                     /db_xref="GI:148244616"
                     /db_xref="GeneID:5172091"
                     /translation="MKSFFTIALLTFTISVNAFWGGNNSHWRNGYQEDNGIFGYNPYD
                     FWDPRWYAEEMGNMFDEFDDNGWNNNYNGYGRNGYGRNGYGRNGYGRNGYGRNGYGFA
                     PNGYVNTPWGPGIAPKVTKPVVPTVK"
     gene            complement(487208..487705)
                     /gene="ssb"
                     /locus_tag="COSY_0468"
                     /db_xref="GeneID:5172583"
     CDS             complement(487208..487705)
                     /gene="ssb"
                     /locus_tag="COSY_0468"
                     /codon_start=1
                     /transl_table=11
                     /product="single-strand DNA binding protein"
                     /protein_id="YP_001219311.1"
                     /db_xref="GI:148244617"
                     /db_xref="GeneID:5172583"
                     /translation="MLGINKVILIGNVGQNIELKYISDGRSVANLSVATNERWIDKNT
                     GQKVDRTEWHRVSLFGKLADIASQYLHKGSKIYIEGKLKTRKWQDKTGTDRYTTEIVV
                     SGLNGTLQMLDRRDNDDDMNNTLQPQQSSPPSSTFTSQQKTVPSVSEPITPIDNSEFD
                     DDIPF"
     misc_feature    complement(487211..487702)
                     /gene="ssb"
                     /locus_tag="COSY_0468"
                     /note="Single-stranded DNA-binding protein [DNA
                     replication, recombination, and repair]; Region: Ssb;
                     COG0629"
                     /db_xref="CDD:223702"
     misc_feature    complement(487397..487687)
                     /gene="ssb"
                     /locus_tag="COSY_0468"
                     /note="SSB_OBF: A subfamily of OB folds similar to the OB
                     fold of ssDNA-binding protein (SSB). SSBs bind with high
                     affinity to ssDNA. They bind to and protect ssDNA
                     intermediates during DNA metabolic pathways. All bacterial
                     and eukaryotic SSBs studied to date...; Region: SSB_OBF;
                     cd04496"
                     /db_xref="CDD:239942"
     misc_feature    complement(order(487412..487414,487421..487423,
                     487454..487456,487481..487483,487544..487546,
                     487550..487552,487595..487603,487676..487687))
                     /gene="ssb"
                     /locus_tag="COSY_0468"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239942"
     misc_feature    complement(order(487403..487405,487409..487411,
                     487448..487453,487457..487459,487463..487465,
                     487487..487492,487529..487531,487535..487537,
                     487541..487543,487547..487549,487553..487558,
                     487592..487597,487616..487618,487646..487648,
                     487664..487672))
                     /gene="ssb"
                     /locus_tag="COSY_0468"
                     /note="ssDNA binding site [nucleotide binding]; other
                     site"
                     /db_xref="CDD:239942"
     misc_feature    complement(order(487469..487471,487475..487477,
                     487481..487483))
                     /gene="ssb"
                     /locus_tag="COSY_0468"
                     /note="tetramer (dimer of dimers) interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239942"
     gene            complement(487720..488895)
                     /locus_tag="COSY_0469"
                     /db_xref="GeneID:5172034"
     CDS             complement(487720..488895)
                     /locus_tag="COSY_0469"
                     /note="putative aromatic compound/drug exporter (ACDE)
                     family in major facilitator superfamily (MFS)"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator family transporter"
                     /protein_id="YP_001219312.1"
                     /db_xref="GI:148244618"
                     /db_xref="GeneID:5172034"
                     /translation="MNKQERVFAFKISLIMTTRMLGLFMIFPIFSVYASKYTNTTPYL
                     IGLAIGIYGLTQALLQIPFGYLSDKYGRKSMLTIGLIIFFIGSIVVANSTDIIGIVIG
                     RALQGSGAISAVLMAFLADFISENQRSKANAFVGVQIGIAFMLALLLGPIISAKLGIS
                     GLFWVIALLSIIALIIVTTMPDIKPKEQYALSIVSIKKVLNIDLLRLDFSIFALHLIL
                     TCAFIAMPIVLKENNIIDIKDSWQIYLPIIMLSFIGMLPMVILASKHKKIKPVFLSAI
                     TLLIISQVLFYQTELTYTSFLILLTLFFIAFNALEAILPSLIASGASADKRGLAMGLY
                     STSQFLGVFVGGISGGRIYNIFNLNSVFLFTTFIAIIWWIIILITKQKTPIKQTAKN"
     misc_feature    complement(487813..488862)
                     /locus_tag="COSY_0469"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(487858..488862)
                     /locus_tag="COSY_0469"
                     /note="Major Facilitator Superfamily; Region: MFS_1;
                     pfam07690"
                     /db_xref="CDD:219516"
     misc_feature    complement(order(487870..487872,487879..487884,
                     487891..487896,487903..487908,487939..487941,
                     487948..487953,487966..487968,487975..487980,
                     487987..487989,488131..488133,488143..488145,
                     488152..488154,488164..488166,488176..488178,
                     488218..488220,488227..488232,488239..488244,
                     488251..488253,488467..488469,488485..488490,
                     488497..488502,488536..488538,488545..488550,
                     488557..488562,488569..488574,488704..488709,
                     488713..488718,488728..488730,488737..488742,
                     488749..488751,488803..488808,488812..488820,
                     488827..488829))
                     /locus_tag="COSY_0469"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(488914..489681)
                     /gene="comL"
                     /locus_tag="COSY_0470"
                     /db_xref="GeneID:5172732"
     CDS             complement(488914..489681)
                     /gene="comL"
                     /locus_tag="COSY_0470"
                     /codon_start=1
                     /transl_table=11
                     /product="competence lipoprotein ComL"
                     /protein_id="YP_001219313.1"
                     /db_xref="GI:148244619"
                     /db_xref="GeneID:5172732"
                     /translation="MKKLFIILPFLVLLLNGCSWQKEIKIESITKGWSPKTFFTQAKE
                     QESLGLTNKAIKLFEQLQATYPGSKYALQSKLEIAYALYKNKDYDQAIYHLNNYIKFY
                     PEHFSTPYAYYLRGVISQDKSRSFLDDYFTDSAQRSVNSVRNAFNYYLALIDKFPKTK
                     YTEDTITRLVALRNILSRHELFIAIYYTKKGANIAAINRTKFIVEKYQNTPSVPAALH
                     LMATNYDAINAGTLAKDTRRVLEKNYPWYTPYYSLKN"
     misc_feature    complement(488947..489633)
                     /gene="comL"
                     /locus_tag="COSY_0470"
                     /note="outer membrane assembly lipoprotein YfiO; Region:
                     OM_YfiO; TIGR03302"
                     /db_xref="CDD:234164"
     misc_feature    complement(489310..489576)
                     /gene="comL"
                     /locus_tag="COSY_0470"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cl02429"
                     /db_xref="CDD:243034"
     misc_feature    complement(order(489316..489321,489328..489333,
                     489340..489345,489430..489435,489442..489447,
                     489451..489456,489550..489555,489562..489567,
                     489571..489576))
                     /gene="comL"
                     /locus_tag="COSY_0470"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     misc_feature    complement(order(489334..489336,489388..489390,
                     489397..489399,489409..489411,489445..489447,
                     489499..489501,489508..489510,489520..489522,
                     489556..489558))
                     /gene="comL"
                     /locus_tag="COSY_0470"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     gene            489779..491881
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /db_xref="GeneID:5172135"
     CDS             489779..491881
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /EC_number="3.1.7.2"
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="YP_001219314.1"
                     /db_xref="GI:148244620"
                     /db_xref="GeneID:5172135"
                     /translation="MKLPDKRILISELCNTLENYMSKKQVEGVYQAYIVAATAHNGQY
                     RQSGEAYVFHPISVAMILAELKLDYCCIVAAILHDCIEDTSVTYEQIKRDFGDEIAHI
                     VEGLSKLTGFEFHSNTDKQAQNFRKLLLAMSGDMRVIVIKLADRLHNMQTLGSMNRDK
                     QLRIAKETVEIHAPIARRLDLNSIRVKLDNLCFAIIYPFRNRVLVSQIKKQCGNRKKI
                     INHIENEIKSRLNQEGLPNVEINGRRKQPCSIYRKMKIKHLKFSQVLDMYALRVIVAD
                     VAQCYQSLGIIHNLYKPLPGKFKDYIALPKSNGYQSLHTVLFGSNKIFIEVQIRSSDM
                     HFISEYGIAAHWYYKSGSNHKSALANNWLGSLLDIQQNSGTSIEFLEETKADLFPSEV
                     FVFTPEGDIIQLPYKSTVLDFAYMVHTSIGNHTLRAKIDQVVTPISTELKSGQTIEII
                     TDDKATPRSSWLQIVVTIKARSSIKAYLKNESASELIQLGEYLLTNALDYQNIDTDNI
                     DEVQWIKCIKALHCNSKEDMYMKIGLSEILVSVALNKLQGDNIKNTIQKISIYKTQGK
                     AISFASCCHPIPGDKVAGVLTTSKGMVVHRLICANLARAKSKNAQWLNIDWQANEDEE
                     FKAMIDVDVANQRGTLASITSVISKMKINIEFLEIQEKNNTIKSLNIVISVANFSQLN
                     QVFVQLKTLKFVREVSRM"
     misc_feature    489788..491878
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /note="Guanosine polyphosphate
                     pyrophosphohydrolases/synthetases [Signal transduction
                     mechanisms / Transcription]; Region: SpoT; COG0317"
                     /db_xref="CDD:223394"
     misc_feature    489923..490288
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /note="Metal dependent phosphohydrolases with conserved
                     &apos;HD&apos; motif; Region: HDc; cd00077"
                     /db_xref="CDD:238032"
     misc_feature    order(489938..489940,490010..490015,490211..490213)
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    490013..490015
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238032"
     misc_feature    490484..490798
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /note="Nucleotidyltransferase (NT) domain of RelA- and
                     SpoT-like ppGpp synthetases and hydrolases; Region:
                     NT_Rel-Spo_like; cd05399"
                     /db_xref="CDD:143389"
     misc_feature    order(490505..490507,490511..490513,490574..490579,
                     490589..490591,490673..490675,490679..490681,
                     490694..490696,490700..490702,490706..490708,
                     490718..490720,490754..490756,490760..490762,
                     490766..490768,490790..490795)
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /note="synthetase active site [active]"
                     /db_xref="CDD:143389"
     misc_feature    order(490505..490507,490673..490675,490679..490681,
                     490694..490696,490700..490702,490706..490708,
                     490718..490720,490754..490756,490760..490762,
                     490790..490792)
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /note="NTP binding site [chemical binding]; other site"
                     /db_xref="CDD:143389"
     misc_feature    order(490574..490576,490754..490756)
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143389"
     misc_feature    490952..491131
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /note="TGS_RelA_SpoT: The RelA (SpoT) protein, also
                     referred to as ppGpp hydrolase/synthetase, is a
                     ribosome-associated protein that is activated during amino
                     acid starvation and thought to mediate the stringent
                     response. RelA contains a TGS domain, named after...;
                     Region: TGS_RelA_SpoT; cd01668"
                     /db_xref="CDD:133438"
     misc_feature    491663..491875
                     /gene="spoT"
                     /locus_tag="COSY_0471"
                     /note="ACT  domain found C-terminal of the RelA/SpoT
                     domains; Region: ACT_RelA-SpoT; cd04876"
                     /db_xref="CDD:153148"
     gene            491956..492150
                     /locus_tag="COSY_0472"
                     /db_xref="GeneID:5172021"
     CDS             491956..492150
                     /locus_tag="COSY_0472"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219315.1"
                     /db_xref="GI:148244621"
                     /db_xref="GeneID:5172021"
                     /translation="MNWTDSLDIAIALNDAYPKINPCIVNFVDLRQMVIALNEFDDDV
                     NKSGEKILEVIQMNWIEERE"
     misc_feature    491956..492147
                     /locus_tag="COSY_0472"
                     /note="Iron-sulphur cluster assembly; Region:
                     Fe-S_assembly; pfam04384"
                     /db_xref="CDD:146824"
     gene            492147..493421
                     /gene="tolB"
                     /locus_tag="COSY_0473"
                     /db_xref="GeneID:5172730"
     CDS             492147..493421
                     /gene="tolB"
                     /locus_tag="COSY_0473"
                     /note="Tol biopolymer transport system, colicin import
                     protein. TonB-ExbB-ExbD/TolA-TolQ-TolR (TonB) family of
                     auxiliary proteins for energization of outer membrane
                     receptor (OMR)-mediated active transport"
                     /codon_start=1
                     /transl_table=11
                     /product="biopolymer transport protein TolB"
                     /protein_id="YP_001219316.1"
                     /db_xref="GI:148244622"
                     /db_xref="GeneID:5172730"
                     /translation="MKQFIVFILSLYTTLSWAVLEVTIFKQEENTFPIVISDFFVVGD
                     ASQGKVIADIMRNNFNRSGEFSVVNANYIIRSKPSFDKWKAKKIEAIVLGKLEKISKK
                     IFNVEIELLDVYSKKTLYKDIFTVHNSGIRRIAHYLSDQIYHALLGKRGFFNTRLAYI
                     TVINKDKGEREYRLEISDSDAQNPQTILKSREPLLSPVWSPKQDKIAYVSFKNSRSEV
                     FIQYPFIRRKIQKLPYFDGIASSPSWHPNGEILLLTLSKNGNKDIYSYQLSSKKLTRL
                     TIDMGIDTEASYSPDGNKIIFTSNRSGQVQVYIKDLKTNKINRATFKGRYNAQAVFSP
                     DGKSLIMVHKIDQDYRIALLDIATKDLKVMTNNQLDESPFFSPNGDMIIFATNQGGFG
                     VLSVVSIWGRQIFELTSKVGEVREPNWSHYLK"
     misc_feature    492156..493412
                     /gene="tolB"
                     /locus_tag="COSY_0473"
                     /note="translocation protein TolB; Provisional; Region:
                     tolB; PRK04922"
                     /db_xref="CDD:179892"
     misc_feature    492204..492485
                     /gene="tolB"
                     /locus_tag="COSY_0473"
                     /note="TolB amino-terminal domain; Region: TolB_N;
                     pfam04052"
                     /db_xref="CDD:217863"
     misc_feature    492963..493073
                     /gene="tolB"
                     /locus_tag="COSY_0473"
                     /note="WD40-like Beta Propeller Repeat; Region: PD40;
                     pfam07676"
                     /db_xref="CDD:203719"
     misc_feature    493230..493316
                     /gene="tolB"
                     /locus_tag="COSY_0473"
                     /note="WD40-like Beta Propeller Repeat; Region: PD40;
                     pfam07676"
                     /db_xref="CDD:203719"
     gene            493433..494002
                     /gene="pal"
                     /locus_tag="COSY_0474"
                     /db_xref="GeneID:5171878"
     CDS             493433..494002
                     /gene="pal"
                     /locus_tag="COSY_0474"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein"
                     /protein_id="YP_001219317.1"
                     /db_xref="GI:148244623"
                     /db_xref="GeneID:5171878"
                     /translation="MLKLISLLIVVLLSSCLSGDDLYRKVLPKSSVVTIEDRMKNVQE
                     NVFETDKSNFTSLRVDDRIKSIPSITESFIVTSFRETDVNFILYFSDDGTEINKTSIK
                     QIIKHANFMRNNPTLKLRLEGHTDERGTREYNLALGENRALNVKEILGLYDLSSRIEV
                     ISFGEEKPMTQQHDEDAWQKNRRVEFVYQ"
     misc_feature    <493682..493996
                     /gene="pal"
                     /locus_tag="COSY_0474"
                     /note="Outer membrane protein and related
                     peptidoglycan-associated (lipo)proteins [Cell envelope
                     biogenesis, outer membrane]; Region: OmpA; COG2885"
                     /db_xref="CDD:225439"
     misc_feature    493685..493993
                     /gene="pal"
                     /locus_tag="COSY_0474"
                     /note="Peptidoglycan binding domains similar to the
                     C-terminal domain of outer-membrane protein OmpA; Region:
                     OmpA_C-like; cd07185"
                     /db_xref="CDD:143586"
     misc_feature    order(493703..493708,493805..493810,493817..493819,
                     493829..493834,493841..493843,493964..493966,
                     493976..493978)
                     /gene="pal"
                     /locus_tag="COSY_0474"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:143586"
     gene            494009..494674
                     /locus_tag="COSY_0475"
                     /db_xref="GeneID:5171892"
     CDS             494009..494674
                     /locus_tag="COSY_0475"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219318.1"
                     /db_xref="GI:148244624"
                     /db_xref="GeneID:5171892"
                     /translation="MYYLGLFIFLSIFILQSAYSGINTEKVVIDHNQKIKRLLLKNKI
                     LIGKFELLEQQQEISTGKIKELFNLITYQKSSGIIKETSFKTREYDKKAKRVYTQARS
                     LLIIEQYDQAIKLFKQYLVDYSNSSYTSDVYYWLAKSYLAKEDFHNAKNTFVVFQQQN
                     PLHYKFSNSLFDLAKVYIELNKQDKAQGLLSTMLVKFPSHKAINRAKQLLSKIIIKSK
                     VNN"
     misc_feature    494297..494632
                     /locus_tag="COSY_0475"
                     /note="tol-pal system protein YbgF; Region: tol_pal_ybgF;
                     TIGR02795"
                     /db_xref="CDD:188247"
     gene            494687..495976
                     /locus_tag="COSY_0476"
                     /db_xref="GeneID:5172691"
     CDS             494687..495976
                     /locus_tag="COSY_0476"
                     /EC_number="2.6.1.85"
                     /note="Similar to anthranilate synthase component I
                     (EC:4.1.3.27) TrpE."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219319.1"
                     /db_xref="GI:148244625"
                     /db_xref="GeneID:5172691"
                     /translation="MKVISIPDIDLDTLSYANPTRYPFLLESVNHNSNNRFSILFAHP
                     GKKIVLNDLEEFDFLDKLTTSIDTLLIYSDLPFTGGWFVYLSYELIGQIEPTLKQIMH
                     TSDQPIAMAVQIPTAIIIDHTNHQTYLLDQFGSKYRIDQVLADIKQLKLIPDCKLTGT
                     LYTEEEAKFLLGVAKNREYIKAGDVFQVNLSRQWQYHLTNDITPTQIYQALKKTNPAP
                     FSALVQLQTFSIISSSPERLFSVDGNVIQSRPIAGTYPRGIGSEDKRLKQQLINHPKE
                     RAEHIMLLDLERNDLGKVCEYGSIKIDEIMGLESYPFVHHIVSNIKGKIKLNTTIKHL
                     ISALFPGGTITGCPKIRCMQIIQELEQTPRQSYTGSLGYVSSNGKMDFNILIRTISKQ
                     NNLLTLRTGAGIVFDSIAKQELQETKHKAKGMLKIFA"
     misc_feature    494687..495973
                     /locus_tag="COSY_0476"
                     /note="hypothetical protein; Validated; Region: PRK09070"
                     /db_xref="CDD:236371"
     misc_feature    494747..495073
                     /locus_tag="COSY_0476"
                     /note="Anthranilate synthase component I, N terminal
                     region; Region: Anth_synt_I_N; pfam04715"
                     /db_xref="CDD:218224"
     misc_feature    495179..495946
                     /locus_tag="COSY_0476"
                     /note="chorismate binding enzyme; Region: Chorismate_bind;
                     pfam00425"
                     /db_xref="CDD:215913"
     gene            complement(496092..497723)
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /db_xref="GeneID:5172512"
     CDS             complement(496092..497723)
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /EC_number="6.3.5.1"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD+ synthase (glutamine-hydrolysing)"
                     /protein_id="YP_001219320.1"
                     /db_xref="GI:148244626"
                     /db_xref="GeneID:5172512"
                     /translation="MQNQLEKLANNSKSIKIDIAQINPIVGDLNGNTQKIIKLTQEAY
                     IRGCDLLVFPELSLIGYPPEDLLLHEGFVQQVQDKVTLINQTISNNISIIFGAPYKKD
                     DILYNSAYLIQNSQVYFYHKQNLPNYGVFDEKRYFESGNEPFIFECQGKKISLVICED
                     AWTSDIISISANKGVQIIISINASPFQIGKHSQRIEQIKQRVLETKTNFIYVNMVGAQ
                     DELVFDGASFAMNSNANITLQLPLFKEAVQSVSFTSPITLFDTDPIEKTIYDALVLAT
                     KDYIEKNDVFNGVVIGLSGGIDSALTLAIAADAIGTEHIKAIMMPYKYTSNISLEDAK
                     IQATTMNVDYHEINIHIIVDSFNTQLNTLFIGMETDTTEENIQARIRGTLLMAISNKL
                     GKIVLTTSNKSEIAVGYTTLYGDMSGGFAPLKDVNKTLVYQLAKYRNTISTIIPERVI
                     DRKPSAELAPNQADQDSLPSYNELDAILTLFIEQKYSVKHIIKQGFNEQTVKYITQMV
                     LNNEYKRRQSAPGPKISPNAFGKERRYPMTSKFQP"
     misc_feature    complement(496101..497681)
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="NAD synthetase; Provisional; Region: PRK13981"
                     /db_xref="CDD:237577"
     misc_feature    complement(496962..497678)
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="Glutamine aminotransferase (GAT, glutaminase)
                     domain of glutamine-dependent NAD synthetases (class 7 and
                     8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570"
                     /db_xref="CDD:143594"
     misc_feature    complement(order(496998..497000,497058..497060,
                     497064..497078,497112..497117,497124..497129,
                     497136..497138,497148..497150,497157..497168,
                     497202..497204,497211..497213,497214..497219,
                     497229..497243,497247..497249,497301..497303,
                     497307..497312,497319..497324,497328..497330,
                     497334..497342,497346..497354,497406..497411,
                     497424..497426,497502..497504,497511..497522,
                     497526..497537,497634..497648))
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="multimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143594"
     misc_feature    complement(order(497154..497156,497238..497240,
                     497247..497252,497325..497327,497331..497333,
                     497340..497342,497346..497348,497358..497360,
                     497559..497561))
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="active site"
                     /db_xref="CDD:143594"
     misc_feature    complement(order(497250..497252,497358..497360,
                     497559..497561))
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:143594"
     misc_feature    complement(order(496998..497000,497058..497060,
                     497064..497072,497076..497078,497112..497117,
                     497124..497129,497136..497138,497148..497150,
                     497157..497168,497214..497219,497229..497243,
                     497247..497249,497301..497303,497328..497330,
                     497334..497342,497346..497354))
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="protein interface 1 [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143594"
     misc_feature    complement(496179..496922)
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="NAD+ synthase is a homodimer, which catalyzes the
                     final step in de novo nicotinamide adenine dinucleotide
                     (NAD+) biosynthesis, an amide transfer from either ammonia
                     or glutamine to nicotinic acid adenine dinucleotide
                     (NaAD). The conversion of NaAD to NAD...; Region:
                     NAD_synthase; cd00553"
                     /db_xref="CDD:238309"
     misc_feature    complement(order(496179..496181,496185..496187,
                     496449..496454,496461..496478,496485..496490,
                     496551..496556,496560..496568,496572..496580,
                     496584..496589,496596..496598,496608..496610,
                     496662..496667,496674..496679,496686..496697,
                     496887..496892,496899..496901,496908..496913))
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238309"
     misc_feature    complement(order(496182..496187,496323..496325,
                     496350..496352,496356..496361,496479..496481,
                     496488..496499,496512..496514,496527..496529,
                     496581..496583,496587..496592,496599..496601,
                     496611..496613,496764..496772,496827..496829,
                     496842..496853))
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="NAD binding pocket [chemical binding]; other site"
                     /db_xref="CDD:238309"
     misc_feature    complement(order(496359..496364,496440..496442,
                     496527..496529,496581..496583,496764..496769,
                     496827..496832,496842..496850))
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="ATP binding pocket [chemical binding]; other site"
                     /db_xref="CDD:238309"
     misc_feature    complement(order(496359..496361,496512..496514,
                     496830..496832,496842..496844))
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="Mg binding site [ion binding]; other site"
                     /db_xref="CDD:238309"
     misc_feature    complement(order(496320..496343,496350..496373,
                     496743..496745))
                     /gene="nadE"
                     /locus_tag="COSY_0477"
                     /note="active-site loop [active]"
                     /db_xref="CDD:238309"
     gene            498452..499435
                     /gene="hemH"
                     /locus_tag="COSY_0478"
                     /db_xref="GeneID:5171994"
     CDS             498452..499435
                     /gene="hemH"
                     /locus_tag="COSY_0478"
                     /EC_number="4.99.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="YP_001219321.1"
                     /db_xref="GI:148244627"
                     /db_xref="GeneID:5171994"
                     /translation="MKIGILLTNIGTPDAPTKASLKRYLSEFLSDSRVVSFPIKFKFI
                     WWLVLNVVILNTRPKKSAKNYAKIWDRIGIGSPLLSITKLQLQGVKKTLLERHENLVF
                     EMGMRYGNPSISSVLNKLLNQDCEKIIVLPLYPQYSNTTTLSTLDVINQVLNDSWTKK
                     PEIIFIEYYCYNDDYIQSLANTVLEHQIKHGKPNKLIISFHGIPQRYIDSGDIYYDHC
                     VDTAKLLAKKLDLNKSDYLFSFQSIFGREPWTKPQTKERLETLACDGVEHIQIICPGF
                     SSDCLETLEEIECENRNYFIQSGGLKFSYIPALNYRDDHIKMLSNLISNYL"
     misc_feature    498455..499432
                     /gene="hemH"
                     /locus_tag="COSY_0478"
                     /note="Ferrochelatase; Region: Ferrochelatase; pfam00762"
                     /db_xref="CDD:216106"
     misc_feature    498458..498970
                     /gene="hemH"
                     /locus_tag="COSY_0478"
                     /note="Ferrochelatase, N-terminal domain: Ferrochelatase
                     (protoheme ferrolyase or HemH) is the terminal enzyme of
                     the heme biosynthetic pathway. It catalyzes the insertion
                     of ferrous iron into the protoporphyrin IX ring yielding
                     protoheme. This enzyme is...; Region: Ferrochelatase_N;
                     cd03411"
                     /db_xref="CDD:239504"
     misc_feature    order(498476..498478,498641..498643,498653..498655,
                     498692..498694,498704..498706,498848..498850,
                     498857..498868,498953..498955,498962..498964)
                     /gene="hemH"
                     /locus_tag="COSY_0478"
                     /note="C-terminal domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239504"
     misc_feature    order(498479..498481,498521..498523,498533..498541,
                     498869..498874)
                     /gene="hemH"
                     /locus_tag="COSY_0478"
                     /note="active site"
                     /db_xref="CDD:239504"
     misc_feature    498980..499381
                     /gene="hemH"
                     /locus_tag="COSY_0478"
                     /note="Ferrochelatase, C-terminal domain: Ferrochelatase
                     (protoheme ferrolyase or HemH) is the terminal enzyme of
                     the heme biosynthetic pathway. It catalyzes the insertion
                     of ferrous iron into the protoporphyrin IX ring yielding
                     protoheme. This enzyme is...; Region: Ferrochelatase_C;
                     cd00419"
                     /db_xref="CDD:238240"
     misc_feature    order(499052..499054,499067..499069,499196..499198,
                     499295..499297)
                     /gene="hemH"
                     /locus_tag="COSY_0478"
                     /note="active site"
                     /db_xref="CDD:238240"
     misc_feature    order(499085..499093,499100..499102,499112..499114,
                     499274..499276,499280..499288,499292..499294,
                     499304..499306,499379..499381)
                     /gene="hemH"
                     /locus_tag="COSY_0478"
                     /note="N-terminal domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238240"
     gene            499543..501819
                     /gene="nrdA"
                     /locus_tag="COSY_0479"
                     /db_xref="GeneID:5172638"
     CDS             499543..501819
                     /gene="nrdA"
                     /locus_tag="COSY_0479"
                     /EC_number="1.17.4.1"
                     /note="Catalyzes the rate-limiting step in dNTP synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     alpha"
                     /protein_id="YP_001219322.1"
                     /db_xref="GI:148244628"
                     /db_xref="GeneID:5172638"
                     /translation="MNQDIKVTKRNGQQESIDMEKIHRVVHWASQDLKSVSVSQVEIN
                     AQLAFFDGIKTEDIHETIIKSAADLISTDIPDYQYLAARLSIFHLRKKAFKSFTPPPF
                     FEHIKKITDLGIYDKDILNKYLKEEIEILGSYIDHWRDMNFSYVAVKQLEGKYLVQNR
                     VTGEIYESPQFLYMLVGMCLFQEYEVSKRMNTVKRFYDAVSLFKISLPTPIMAGVRTP
                     TRQFSSCVLIETDDDLDSISATAGVIVKYISQRAGIGINGGKIRAIGSPIRGGEATHT
                     GCIPFYKHFHTAVKSCSQGGVRGGAATLFYPLWHLEVENLLVLKNNTGTDENRIRHLD
                     YGVQFNGLMYQRFLKDGDITLFSPHDTPDLYNAFFADQEEFKRLYHKYEQNTLIRKHT
                     IKARELFSKFIQERANTGRIYLQNVDHCNTHSAFNAKQAPIKQSNLCMEITLPTKPLY
                     SIQDEQGEIALCTLSAVNLGALDSLNELETLTDIIVRSLDCLLDYQDYPIKAAELASK
                     NRRTLGIGVTNLAYYLAKNGAKYSDGSGNQLIHTTFEALQYYSLKASNTLAKELGACP
                     LFFQTQYSQGIMPIDSYKKDIDAFCDFKLKFDWDTLRQDITSKGLRNSTLTALMPCES
                     SSQISNSTNGIEPPRGFVSIKQSKDGILKQIVPDYELLKNQYELLWDIKDNEGYLQLC
                     GIMQKFVDQSISTNTHYDPSQFEGNKVPIKLFLMDLLKAYKYGIKTLYYHTTRDGGSN
                     DMSEKEDDNNCTNGICKL"
     misc_feature    499552..501816
                     /gene="nrdA"
                     /locus_tag="COSY_0479"
                     /note="ribonucleotide-diphosphate reductase subunit alpha;
                     Validated; Region: PRK09103"
                     /db_xref="CDD:181649"
     misc_feature    499555..499818
                     /gene="nrdA"
                     /locus_tag="COSY_0479"
                     /note="ATP cone domain; Region: ATP-cone; pfam03477"
                     /db_xref="CDD:217585"
     misc_feature    500047..501744
                     /gene="nrdA"
                     /locus_tag="COSY_0479"
                     /note="Class I ribonucleotide reductase; Region: RNR_I;
                     cd01679"
                     /db_xref="CDD:153088"
     misc_feature    order(500167..500172,500212..500217,500299..500301,
                     500851..500853,500857..500859,500863..500865,
                     500932..500934,501400..501417)
                     /gene="nrdA"
                     /locus_tag="COSY_0479"
                     /note="active site"
                     /db_xref="CDD:153088"
     misc_feature    order(500203..500205,500242..500247,500254..500256,
                     500263..500268,500275..500280,500287..500289,
                     500332..500334,500368..500370,500380..500385,
                     500389..500394,500401..500406,500413..500427)
                     /gene="nrdA"
                     /locus_tag="COSY_0479"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:153088"
     misc_feature    order(500215..500217,500851..500853,500857..500859,
                     500863..500865,500926..500928,501730..501735)
                     /gene="nrdA"
                     /locus_tag="COSY_0479"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:153088"
     misc_feature    order(500236..500244,500251..500253,500287..500289,
                     500326..500328,500368..500370,500383..500385)
                     /gene="nrdA"
                     /locus_tag="COSY_0479"
                     /note="effector binding site; other site"
                     /db_xref="CDD:153088"
     misc_feature    order(500563..500565,500572..500577,500581..500586,
                     500728..500730,500740..500742,500761..500763,
                     501670..501678,501682..501687,501697..501702,
                     501706..501711)
                     /gene="nrdA"
                     /locus_tag="COSY_0479"
                     /note="R2 peptide binding site; other site"
                     /db_xref="CDD:153088"
     gene            501835..502971
                     /gene="nrdB"
                     /locus_tag="COSY_0480"
                     /db_xref="GeneID:5171960"
     CDS             501835..502971
                     /gene="nrdB"
                     /locus_tag="COSY_0480"
                     /EC_number="1.17.4.1"
                     /note="B2 or R2 protein; type 1a enzyme; catalyzes the
                     rate-limiting step in dNTP synthesis; converts nucleotides
                     to deoxynucleotides; forms a homodimer and then a
                     multimeric complex with NrdA"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="YP_001219323.1"
                     /db_xref="GI:148244629"
                     /db_xref="GeneID:5171960"
                     /translation="MSYSIFTKTISNILIEPMFFGNTVNVARFDKQKFEIFEKLTEKQ
                     LSFFWRPEEIDVSKDKIDFAKLLPNEKHIFISNLQYQILLDSVQSRSPNIAFLPIVSL
                     PELENWIETWSFSETIHSRSYTHIIRAIVNEPGIVFDDIMKIDEIIQRAESVSKHYNE
                     LIKCTQAYLLHGIGKFKVQDKEILIDLYCLKKQLYLTIMSVNILEAVQFYVSFACSFA
                     FAERKVMEGNAKIIRMIARDEALHLTGTQHILNLMSDGKDDPDMKKIAKECEKEVITM
                     FKEACEQEKDWAEYLFRDGSMIGLNAKMLKQYLEYITNVRMKALNLSPVFDECINPLP
                     WINHWLDSDNVQVAPQETEITSYLVSAIDNTLDKQDFDFNSFKL"
     misc_feature    501919..502857
                     /gene="nrdB"
                     /locus_tag="COSY_0480"
                     /note="Ribonucleotide Reductase, R2/beta subunit,
                     ferritin-like diiron-binding domain; Region: RNRR2;
                     cd01049"
                     /db_xref="CDD:153108"
     misc_feature    order(501946..501948,501967..501969,502162..502167,
                     502174..502176,502183..502188,502195..502197,
                     502204..502206,502246..502251,502258..502260)
                     /gene="nrdB"
                     /locus_tag="COSY_0480"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:153108"
     misc_feature    order(501979..501981,502087..502089,502180..502182,
                     502189..502191,502201..502203,502543..502548,
                     502558..502560)
                     /gene="nrdB"
                     /locus_tag="COSY_0480"
                     /note="putative radical transfer pathway; other site"
                     /db_xref="CDD:153108"
     misc_feature    order(502087..502089,502180..502182,502189..502191,
                     502447..502449,502549..502551,502558..502560)
                     /gene="nrdB"
                     /locus_tag="COSY_0480"
                     /note="diiron center [ion binding]; other site"
                     /db_xref="CDD:153108"
     misc_feature    502201..502203
                     /gene="nrdB"
                     /locus_tag="COSY_0480"
                     /note="tyrosyl radical; other site"
                     /db_xref="CDD:153108"
     gene            502980..503243
                     /locus_tag="COSY_0481"
                     /db_xref="GeneID:5172357"
     CDS             502980..503243
                     /locus_tag="COSY_0481"
                     /note="2Fe-2S iron-sulfur cluster binding domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219324.1"
                     /db_xref="GI:148244630"
                     /db_xref="GeneID:5172357"
                     /translation="MFRIEIDNINGKTKSLYAYGDHSILIELEQQNILINHSCRQGHC
                     GSCILQLLSGDVIHQDSIIHLSQGEILACRATPVTDIKIASRN"
     misc_feature    <503088..503228
                     /locus_tag="COSY_0481"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    order(503094..503096,503103..503105,503109..503120,
                     503193..503198)
                     /locus_tag="COSY_0481"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    order(503094..503096,503109..503111,503118..503120,
                     503196..503198)
                     /locus_tag="COSY_0481"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     gene            complement(503429..504097)
                     /locus_tag="COSY_0482"
                     /db_xref="GeneID:5172511"
     CDS             complement(503429..504097)
                     /locus_tag="COSY_0482"
                     /note="Similar to dUTP diphosphatase."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219325.1"
                     /db_xref="GI:148244631"
                     /db_xref="GeneID:5172511"
                     /translation="MSKIKQMFELQKQLNNNTNGVQWTDGITKDGRYISWLRCIYMEA
                     TEAIDSFNWKHWKDIKKEHDLDNFKVELVDIWHFIMSEAIHLGDTQFAHNYENIKPER
                     EVNPELVIEILEKLVAIASSANVNKSQNALYEITGLFFKALTTMSMDVSELYKRYLVK
                     NQLNIFRQKHGYKKGTYIKLWGVEEDNVVAFRIMEKHSDLMPEQLYKELEKEYTLHNF
                     LLNK"
     misc_feature    complement(503582..504091)
                     /locus_tag="COSY_0482"
                     /note="dUTPase; Region: dUTPase_2; pfam08761"
                     /db_xref="CDD:220008"
     misc_feature    complement(503840..504079)
                     /locus_tag="COSY_0482"
                     /note="Nucleoside Triphosphate Pyrophosphohydrolase (EC
                     3.6.1.8) MazG-like domain found in dimeric 2-Deoxyuridine
                     5&apos;-triphosphate nucleotidohydrolase and similar
                     proteins; Region: NTP-PPase_dUTPase; cd11527"
                     /db_xref="CDD:212134"
     misc_feature    complement(order(503864..503869,503876..503878,
                     503885..503887,503960..503962,503969..503971,
                     503990..503992,504041..504046,504053..504058,
                     504065..504067))
                     /locus_tag="COSY_0482"
                     /note="active site"
                     /db_xref="CDD:212134"
     misc_feature    complement(order(503864..503866,503921..503941,
                     503951..503956,503963..503965,503972..503977,
                     503981..503986,503990..503992,504041..504046))
                     /locus_tag="COSY_0482"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:212134"
     misc_feature    complement(order(503876..503878,503885..503887,
                     503960..503962,503969..503971))
                     /locus_tag="COSY_0482"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:212134"
     gene            complement(504370..504951)
                     /gene="rnt"
                     /locus_tag="COSY_0483"
                     /db_xref="GeneID:5172364"
     CDS             complement(504370..504951)
                     /gene="rnt"
                     /locus_tag="COSY_0483"
                     /EC_number="3.1.13.-"
                     /note="Responsible for the end-turnover of tRNA:
                     specifically removes the terminal AMP residue from
                     uncharged tRNA (tRNA-C-C-A)"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="YP_001219326.1"
                     /db_xref="GI:148244632"
                     /db_xref="GeneID:5172364"
                     /translation="MLIKDRIRGYLPVVIDIETGGFNEKTDAMLEICTIIIGIDKMNN
                     LYPKKPQHFHIEPFKGSILEPSAIKFNSIDVDNPFRMAVKEVDAIKQIYTKVYTELKQ
                     KDCTRAILVGHNAFFDLGFLRAATNRCKLKSPFHQFSTLDTVSLSALCYGETVLAKAI
                     RKADIEWDDTCAHSALYDTQKTAELFCKVFNTQ"
     misc_feature    complement(<504388..504951)
                     /gene="rnt"
                     /locus_tag="COSY_0483"
                     /note="DNA polymerase III, epsilon subunit and related
                     3&apos;-5&apos; exonucleases [DNA replication,
                     recombination, and repair]; Region: DnaQ; COG0847"
                     /db_xref="CDD:223916"
     misc_feature    complement(504373..504936)
                     /gene="rnt"
                     /locus_tag="COSY_0483"
                     /note="DEDDh 3&apos;-5&apos; exonuclease domain of RNase
                     T; Region: RNaseT; cd06134"
                     /db_xref="CDD:99837"
     misc_feature    complement(order(504373..504375,504493..504498,
                     504505..504510,504517..504519,504526..504540,
                     504604..504606,504928..504930,504934..504936))
                     /gene="rnt"
                     /locus_tag="COSY_0483"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:99837"
     misc_feature    complement(order(504418..504420,504433..504435,
                     504598..504600,504898..504900,504904..504906))
                     /gene="rnt"
                     /locus_tag="COSY_0483"
                     /note="catalytic site [active]"
                     /db_xref="CDD:99837"
     misc_feature    complement(order(504418..504420,504433..504435,
                     504598..504606,504610..504615,504889..504891,
                     504895..504906))
                     /gene="rnt"
                     /locus_tag="COSY_0483"
                     /note="putative active site [active]"
                     /db_xref="CDD:99837"
     misc_feature    complement(order(504418..504420,504433..504435,
                     504601..504606,504610..504615,504889..504891,
                     504895..504906))
                     /gene="rnt"
                     /locus_tag="COSY_0483"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:99837"
     gene            complement(504941..505366)
                     /locus_tag="COSY_0484"
                     /db_xref="GeneID:5172578"
     CDS             complement(504941..505366)
                     /locus_tag="COSY_0484"
                     /note="Similar to the C-terminal region of amino-acid
                     N-acetyltransferase ArgA (477 aa) in Ralstonia eutropha
                     JMP134."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219327.1"
                     /db_xref="GI:148244633"
                     /db_xref="GeneID:5172578"
                     /translation="MIKAEQILTLVKPFSEEGKILIRTEAQINENIGDFVYLTNNNQL
                     IACAGLKDCKEDNMGEIYSLAVSKKAQKTGLSLKLLEKIMFKAKAKKFSKVFALTKHS
                     TDWFIKHGFIQMNIIDLPQKHQALFNQERNSSIFFKNVN"
     misc_feature    complement(<505115..505264)
                     /locus_tag="COSY_0484"
                     /note="N-Acyltransferase superfamily: Various enzymes that
                     characteristically catalyze the transfer of an acyl group
                     to a substrate; Region: NAT_SF; cd04301"
                     /db_xref="CDD:173926"
     misc_feature    complement(order(505136..505141,505169..505177))
                     /locus_tag="COSY_0484"
                     /note="Coenzyme A binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173926"
     gene            505443..507107
                     /gene="ilvD"
                     /locus_tag="COSY_0485"
                     /db_xref="GeneID:5172644"
     CDS             505443..507107
                     /gene="ilvD"
                     /locus_tag="COSY_0485"
                     /EC_number="4.2.1.9"
                     /note="catalyzes the dehydration of
                     2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate
                     in valine and isoleucine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="YP_001219328.1"
                     /db_xref="GI:148244634"
                     /db_xref="GeneID:5172644"
                     /translation="MCIPRKYSSQVVDGFERAPSRAMLYPIGFKKDDFSKPQVGIAST
                     WSMVTPCNMHINKLADKAEKGINNAGGKGVIFNTITISDGISMGSEGMKYSLVSREVI
                     ADSIETVVGCQGFDGVVAIGGCDKNMPGCIIGLARLNRPSIFVYGGTIQPGKNRTDVV
                     SVFEAVGRFSNHEIDEIELENIEKTAVTGAGSCGGMYTANTMASAIEALGMSLPNSSA
                     QNAISDDKNNDCIQAGEAILTLLNKDIKPRDIMTMKAFENAITVIIALGGSTNAVLHL
                     IAMANAAEVNLKIDDFTRIGKKVPVIADLKPSGKYMMSELVEIGGTLPLMKMLLDAGL
                     LHGDCMTVTGKTLAKNLKNVQSYADSQEIIRALDNPIKKDSHLRILRGNLAINGAVAK
                     ITGKEGSSFKGTAKCFSHEEGALKAILNDQIKAGNVIVIRYEGPVGGPGMREMLAPTS
                     AVMGKGLGGKIALITDGRFSGGTHGFVVGHITPEAFKGGVLAVVEDGDEIIIDAQNNV
                     LELLVDQAIIDKRLSKWTQPKPNYTKGVLAKFAKLAKSASEGAVTD"
     misc_feature    505458..507104
                     /gene="ilvD"
                     /locus_tag="COSY_0485"
                     /note="dihydroxy-acid dehydratase; Provisional; Region:
                     PRK00911"
                     /db_xref="CDD:234861"
     gene            complement(507173..509290)
                     /gene="vacB"
                     /locus_tag="COSY_0486"
                     /db_xref="GeneID:5172550"
     CDS             complement(507173..509290)
                     /gene="vacB"
                     /locus_tag="COSY_0486"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="YP_001219329.1"
                     /db_xref="GI:148244635"
                     /db_xref="GeneID:5172550"
                     /translation="MSDFHYKKESKKYDNSIPSRKYILSFFEKKSRTLHELYDLLTID
                     YHQKKPLSHRLKAMVRDQQLNFDQHGVYHKFSAKNGVITGKVIANPKGFGFIALDKGG
                     KDLRLSLKQMQLVFHGDKVEARLLNQRGDAQIIKVIKSIKTVVGRLHLEKKYAYVVVD
                     DKRIKNNISILKINKEHHDKQIVIVKIIRSPTLKSLAIGEIIQILGIYMDKGMETDSA
                     LYRNSIPVDFSLGAFEQISKLPTVVTDSDKIGRIDITKIKLVTIDGEDSRDFDDAVYA
                     EVTSKGWKLIVAIADVSHYVKEGSDLDKDALDRGNSVYFPRRVVPMLPEILSNGLCSI
                     NPGVERLCVTCEMNIDTHGNLLDYKFYPAVMLSHARLTYTKVNQILKHHDTDLTKYYA
                     PVMDNLNALYNLYKSLRTSRIKRGVMDFDRIESKILFNNNGKISNIVDCSRNDAHKLI
                     EECMLMANQATAKFLNHHNEDFLYRIHPKPTVEKVEVTRQFLTTIGLTLEGGIQPESK
                     DFAKILEYSKGRNDENIIKTIVLRTMKQAVYTPNNEGHFGLAFKDYTHFTSPIRRYPD
                     LLVHRAIKRVLNKKGKKPSKKMLEIGTHLSMTERRADDASRDVEQWLKCEYMLNKVGN
                     RFNGVISGIASFGIFIELTDIFVEGMIALCDMKDDYYIFDNINHQLKGEPTGKVYQLG
                     NTIKIQVTSVNLDNRQIIFSPIE"
     misc_feature    complement(507185..509242)
                     /gene="vacB"
                     /locus_tag="COSY_0486"
                     /note="ribonuclease R; Region: RNase_R; TIGR02063"
                     /db_xref="CDD:233703"
     misc_feature    complement(<508904..509041)
                     /gene="vacB"
                     /locus_tag="COSY_0486"
                     /note="Ribonuclease B OB domain; Region: OB_RNB;
                     pfam08206"
                     /db_xref="CDD:203875"
     misc_feature    complement(507560..508540)
                     /gene="vacB"
                     /locus_tag="COSY_0486"
                     /note="RNB domain; Region: RNB; pfam00773"
                     /db_xref="CDD:216112"
     misc_feature    complement(507179..507427)
                     /gene="vacB"
                     /locus_tag="COSY_0486"
                     /note="S1_RNase_R: RNase R C-terminal S1 domain. RNase R
                     is a processive 3&apos; to 5&apos; exoribonuclease, which
                     is a homolog of RNase II. RNase R degrades RNA with
                     secondary structure having a 3&apos; overhang of at least
                     7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R;
                     cd04471"
                     /db_xref="CDD:239917"
     misc_feature    complement(order(507335..507337,507341..507343,
                     507374..507376,507398..507400))
                     /gene="vacB"
                     /locus_tag="COSY_0486"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:239917"
     gene            complement(509294..510610)
                     /gene="purA"
                     /locus_tag="COSY_0487"
                     /db_xref="GeneID:5171852"
     CDS             complement(509294..510610)
                     /gene="purA"
                     /locus_tag="COSY_0487"
                     /EC_number="6.3.4.4"
                     /note="catalyzes the formation of
                     N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine
                     monophosphate and GTP in AMP biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthetase"
                     /protein_id="YP_001219330.1"
                     /db_xref="GI:148244636"
                     /db_xref="GeneID:5171852"
                     /translation="MSKNVVIIGTQWGDEGKGKIVDLISDRAVSVVRFQGGHNAGHTL
                     VIDQQTTVLHLIPSGILHDHVECLIAHGVVLSMSALLKEIAELEGANINVTERLKISP
                     GCPLIFPYHIALDNAREAKCGKTAIGTTGNGIGPTYEDKVARRGLRAGDLLNPILFAS
                     KLKEVVEYHNFLLTNYYGTAPVDYQVILYEALSQAKKIKHMIIDVTEKIHQHIANDEN
                     ILFEGAQGTLLDIDQGTYPFVTSSNTTSGGAVTGSGVGVTDINYVLGIVKAYTTRVGS
                     GPFPTELIYNVSTNKGDAIGKVLGTVGHEFGATTGRQRRCGWLDMVTLKRSFNLNAVT
                     GICLTKLDVLDSLISVKICVAYKLNGKEVTIPPYDAKGYTDAKPVYIEMPGWKTSTIG
                     TNSFDSLPIEAQNYIHKIEQLANLPVDILSTGPDRTQTLILKHPFE"
     misc_feature    complement(509315..510601)
                     /gene="purA"
                     /locus_tag="COSY_0487"
                     /note="Adenylosuccinate synthetase; Region:
                     Adenylsucc_synt; smart00788"
                     /db_xref="CDD:197875"
     misc_feature    complement(509336..510601)
                     /gene="purA"
                     /locus_tag="COSY_0487"
                     /note="Adenylosuccinate synthetase (AdSS) catalyzes the
                     first step in the de novo biosynthesis of AMP. IMP and
                     L-aspartate are conjugated in a two-step reaction
                     accompanied by the hydrolysis of GTP to GDP in the
                     presence of Mg2+. In the first step, the...; Region: AdSS;
                     cd03108"
                     /db_xref="CDD:239382"
     misc_feature    complement(order(509336..509341,509585..509587,
                     509591..509593,510476..510478,510482..510490,
                     510557..510565,510569..510571))
                     /gene="purA"
                     /locus_tag="COSY_0487"
                     /note="GDP-binding site [chemical binding]; other site"
                     /db_xref="CDD:239382"
     misc_feature    complement(order(510485..510487,510554..510556,
                     510563..510565))
                     /gene="purA"
                     /locus_tag="COSY_0487"
                     /note="ACT binding site; other site"
                     /db_xref="CDD:239382"
     misc_feature    complement(order(509891..509893,509936..509938,
                     510221..510223,510230..510232,510494..510496))
                     /gene="purA"
                     /locus_tag="COSY_0487"
                     /note="IMP binding site; other site"
                     /db_xref="CDD:239382"
     gene            complement(510637..511587)
                     /gene="hisZ"
                     /locus_tag="COSY_0488"
                     /db_xref="GeneID:5172505"
     CDS             complement(510637..511587)
                     /gene="hisZ"
                     /locus_tag="COSY_0488"
                     /note="histidine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="YP_001219331.1"
                     /db_xref="GI:148244637"
                     /db_xref="GeneID:5172505"
                     /translation="MWQLPESIEELTNDQALVFESLRRHLLDLYADKGFGLVIPPMVE
                     HVNSLLLTNDVVDEKTFKFLDPNSGKMLGVHADITPQIARIDAKRGSDSVEKYCYINS
                     ILKTKADDFYASRSPIQAGAELYGSDATESDVEVIELMLESLKLLSIDSVILILGNVA
                     IFDSLTEQENISIQAVAHLRAIFSRRSMPDLAVFLNNNTLKNADLFIHLIKLEGDSDI
                     LDKALIIFGHFEQARIAIEDLIIIDKQLLEKGIKAIFDLSELQAYEYHTGVVFSAYNK
                     NYSKALAQGGRYNDIGKSFGKSRAATGFSFDLKFLSQSHF"
     misc_feature    complement(510655..511566)
                     /gene="hisZ"
                     /locus_tag="COSY_0488"
                     /note="Histidyl-tRNA synthetase; Region: tRNA-synt_His;
                     pfam13393"
                     /db_xref="CDD:222097"
     misc_feature    complement(510661..511545)
                     /gene="hisZ"
                     /locus_tag="COSY_0488"
                     /note="Class II Histidinyl-tRNA synthetase (HisRS)-like
                     catalytic core domain. HisRS is a homodimer. It is
                     responsible for the attachment of histidine to the 3&apos;
                     OH group of ribose of the appropriate tRNA. This domain is
                     primarily responsible for...; Region: HisRS-like_core;
                     cd00773"
                     /db_xref="CDD:238396"
     misc_feature    complement(order(510676..510681,510730..510732,
                     511174..511176,511183..511185,511195..511197,
                     511219..511221,511258..511263,511321..511326,
                     511333..511338,511351..511353,511357..511359,
                     511396..511401,511459..511479,511492..511494,
                     511528..511530))
                     /gene="hisZ"
                     /locus_tag="COSY_0488"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238396"
     misc_feature    complement(511459..511485)
                     /gene="hisZ"
                     /locus_tag="COSY_0488"
                     /note="motif 1; other site"
                     /db_xref="CDD:238396"
     misc_feature    complement(order(510667..510669,510676..510678,
                     510730..510732,510745..510747,510790..510795,
                     510799..510801,510805..510807,511219..511221,
                     511231..511233,511255..511257,511264..511266,
                     511351..511353,511357..511359))
                     /gene="hisZ"
                     /locus_tag="COSY_0488"
                     /note="active site"
                     /db_xref="CDD:238396"
     misc_feature    complement(510667..510681)
                     /gene="hisZ"
                     /locus_tag="COSY_0488"
                     /note="motif 3; other site"
                     /db_xref="CDD:238396"
     gene            complement(511600..512457)
                     /gene="hflC"
                     /locus_tag="COSY_0489"
                     /db_xref="GeneID:5172435"
     CDS             complement(511600..512457)
                     /gene="hflC"
                     /locus_tag="COSY_0489"
                     /note="protease specific for phage lambda CII repressor"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protease subunit HflC"
                     /protein_id="YP_001219332.1"
                     /db_xref="GI:148244638"
                     /db_xref="GeneID:5172435"
                     /translation="MQKIGLALIAVLFLVLSSVVYTVNETQTAIKLRLGEIVSVEKVP
                     GLKFKMPFVNNIVKFDHRIQTLDAPSERFLTGEKKNVIVDSYVKWRIEDAEQFYKSTG
                     GNIARTNNRLAQIIKTGLKSEFSKRTIADVVSGERSEIMANIARLAKKDIAQFGIKII
                     DVRIKRIDLSQEVSNSVYRRMQAERQRVAKEFRSKGAEKAEIIKAAADKERTIILANA
                     YRDSEKIRGEGDAVSANNYAKAYSKNSDFYVFYRSLESYKKSFSNQNNILVLNPNTEF
                     FRYFNPQIK"
     misc_feature    complement(511615..512457)
                     /gene="hflC"
                     /locus_tag="COSY_0489"
                     /note="HflC protein; Region: hflC; TIGR01932"
                     /db_xref="CDD:233644"
     misc_feature    complement(511675..512400)
                     /gene="hflC"
                     /locus_tag="COSY_0489"
                     /note="Band_7_HflC: The band 7 domain of flotillin
                     (reggie) like proteins. This group includes proteins
                     similar to prokaryotic HlfC (High frequency of
                     lysogenization C). Although many members of the band 7
                     family are lipid raft associated, prokaryote plasma...;
                     Region: Band_7_HflC; cd03405"
                     /db_xref="CDD:239499"
     gene            complement(512457..513626)
                     /gene="hflK"
                     /locus_tag="COSY_0490"
                     /db_xref="GeneID:5172407"
     CDS             complement(512457..513626)
                     /gene="hflK"
                     /locus_tag="COSY_0490"
                     /note="protease specific for phage lambda CII repressor"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protease subunit HflK"
                     /protein_id="YP_001219333.1"
                     /db_xref="GI:148244639"
                     /db_xref="GeneID:5172407"
                     /translation="MAWNDNNNKNPWNGNNQTPPELEKVIKDMKNKFDGFLNGKKSSN
                     TITPKIPSNGNLKYILILILFIWLLSGIYIIDPAEKGVILRFGAFQEETSQGPHWHIP
                     YPIETLNRINVEQIRTSEIGYRNTVNNNRRFGSNVSSESLMLTKDENMIEAKFAVQYK
                     INNVQDYLFNVVKPDTTLRHVSESAIRQIVGQNTMDYILTEGRVNIADDIKIKSQSLL
                     DKYKTGLLITTVNMQDAQPPEQVQSAFSDAVKAREDKQRLINEAQTYANDILPKSRGK
                     AVRMLEESKAYKSEIVSKSEGETSRFKQILAEYEKAPKVTKERLYRETMENVLATTSK
                     VMVDSKTNNMMYLPIDKLINAKQANAQVTIQESSIKQNNQGSSNVRDIFRNRGGR"
     misc_feature    complement(513504..>513578)
                     /gene="hflK"
                     /locus_tag="COSY_0490"
                     /note="Bacterial membrane protein N terminal; Region:
                     HflK_N; pfam12221"
                     /db_xref="CDD:221467"
     misc_feature    complement(512577..513410)
                     /gene="hflK"
                     /locus_tag="COSY_0490"
                     /note="HflK protein; Region: hflK; TIGR01933"
                     /db_xref="CDD:130988"
     misc_feature    complement(512640..513410)
                     /gene="hflK"
                     /locus_tag="COSY_0490"
                     /note="Band_7_HflK: The band 7 domain of flotillin
                     (reggie) like proteins. This group includes proteins
                     similar to prokaryotic HlfK (High frequency of
                     lysogenization K). Although many members of the band 7
                     family are lipid raft associated, prokaryote plasma...;
                     Region: Band_7_HflK; cd03404"
                     /db_xref="CDD:239498"
     gene            513749..515980
                     /locus_tag="COSY_0491"
                     /db_xref="GeneID:5172646"
     CDS             513749..515980
                     /locus_tag="COSY_0491"
                     /note="Similar to organic solvent tolerance protein OstA."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219334.1"
                     /db_xref="GI:148244640"
                     /db_xref="GeneID:5172646"
                     /translation="MREYTIIMQKQLALCLLLAFLSNTISAGSLILNCKNNVLLFPEQ
                     ILSTETKDLNIQANYSEIYKGDSYFLKGNVSLNSSTYFLGADEISINKPSKISTATGY
                     VKFQNNELMLTGDKAMIKKQGEMIYTTLNQVKFYYPNLKIKGRAQFVTHDGTEQIFNS
                     GSYSLCPLGNSDWQMKADKIILNSTTNKGIAKNVTIEFLGITIFYSPYQEWVLKGRSS
                     GFLAPIFGSYNELGVSGGSNYQVKIPYYFNIAPDRDFFLILNQLSSRGSVFEGKYRQL
                     ITDNNYLGNGRSEIEGHYLLNKDKITNSRRWLLNSKLDLSLNAKTDLSIVTSRVSDSD
                     YFKEIAHSNTSDSKLRSYVNLSYKNQKKNLTMSFFIESEQLINNGSASYTRVPELSIN
                     KKYKGLDGRNVVFSLISTKFTHKNSNTTTNKTGIRTHAQTKFSRSLKTNNYSITPSLK
                     LSTTNYTMDDAVHQERNIVSFGFDSKFFLERRVFLFGTHLTQTLTPRLGYNYTPKKDQ
                     STLPNFDSDDKNNLYESLFSGQKFTGIDRIASANDLIFGLESDFINEETGGTYLSLKI
                     AQAYQFDDMSMNRNGTLVSQKKYSNVAMSANLTMRDFSFNNSLQYNSRTNKISKRNSS
                     ISFIINSRKFLTLAHYVDNGNNSVELYSAYPLTQQTHVFAGINGSISNSIINKETIGI
                     AYESCCWAVRLAYFKEYLNENNYDYVAKFELVLKGLATTSSNLYKRLKEDIPNYSVNL
                     NDF"
     misc_feature    513899..515902
                     /locus_tag="COSY_0491"
                     /note="Organic solvent tolerance protein OstA [Cell
                     envelope biogenesis, outer membrane]; Region: Imp;
                     COG1452"
                     /db_xref="CDD:224369"
     misc_feature    514664..515593
                     /locus_tag="COSY_0491"
                     /note="Organic solvent tolerance protein; Region: OstA_C;
                     pfam04453"
                     /db_xref="CDD:218093"
     gene            515970..516863
                     /locus_tag="COSY_0492"
                     /db_xref="GeneID:5172303"
     CDS             515970..516863
                     /locus_tag="COSY_0492"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219335.1"
                     /db_xref="GI:148244641"
                     /db_xref="GeneID:5172303"
                     /translation="MIFKMNKTLLLICVFSFNIFAIPNSIVAIVNDDLITFDQISIDI
                     KPNYTKAQKLTLVNQQIDLILQLQKIKQLSIVPKENVINSMLGNIALNNDLSLIQLQS
                     LPQFDKVINHVKQNLSLEGLKHFIIENLNIELTDVEISKQLSKTPNHLNKLEKQIRIA
                     QITINSTNQVDSNRLIKDRLIDLSEKINKGDSFSILKKIYSQDNFYKNDSESIWLNLS
                     KLPKAFQQSLKGLLVGEISQPFKIGQVWRIVKIIDKRSVDNYLVELKAKLIRQKEDTY
                     FYNWVKKIRKEAYIKIFDNKL"
     misc_feature    516495..516728
                     /locus_tag="COSY_0492"
                     /note="PPIC-type PPIASE domain; Region: Rotamase_2;
                     cl08278"
                     /db_xref="CDD:244886"
     gene            516864..517607
                     /locus_tag="COSY_0493"
                     /db_xref="GeneID:5172601"
     CDS             516864..517607
                     /locus_tag="COSY_0493"
                     /note="23S rRNA (guanosine-2'-O-)-methyltransferase RlmB"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="YP_001219336.1"
                     /db_xref="GI:148244642"
                     /db_xref="GeneID:5172601"
                     /translation="MSKSIIITGFHAIQAQLKFNPKYLIKIFILNKRCDKRLNTLILE
                     INNFDINIQQCTKVQLDKLSNYQTHQGIAAEILLPILPNQCELITYVSKLDNASLILI
                     LDSIQDPRNLGACLRSANAAGVDCVIINKDGSASISALVHKTSAGAINQIKIFQVTNL
                     SRTIKALQQQNIWVIGLDSSANTLIYQIDLTTPNAIIMGSEGFGLKRLTKQSCDQLAK
                     IPMQGKVESLNVSVATGITLFEINRQRFL"
     misc_feature    516870..517598
                     /locus_tag="COSY_0493"
                     /note="23S rRNA (guanosine-2&apos;-O-)-methyltransferase;
                     Provisional; Region: PRK11181"
                     /db_xref="CDD:183021"
     misc_feature    516882..517091
                     /locus_tag="COSY_0493"
                     /note="RNA 2&apos;-O ribose methyltransferase substrate
                     binding; Region: SpoU_sub_bind; smart00967"
                     /db_xref="CDD:214943"
     misc_feature    517155..517580
                     /locus_tag="COSY_0493"
                     /note="SpoU rRNA Methylase family; Region: SpoU_methylase;
                     pfam00588"
                     /db_xref="CDD:216010"
     gene            complement(517828..519018)
                     /locus_tag="COSY_0494"
                     /db_xref="GeneID:5171883"
     CDS             complement(517828..519018)
                     /locus_tag="COSY_0494"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219337.1"
                     /db_xref="GI:148244643"
                     /db_xref="GeneID:5171883"
                     /translation="MIENNINKLDLQVVKAKLTKARTQLILDQPFLGNLVLRLPLKAA
                     GSWCKTSATDAKSFYYNPNFINQLDHHQTKFILIHEVLHCALMHFSRRGNRLKHKWDL
                     ACDFAINPLLVKEGFHPPPGLSIFHKYQGMIAEEIYPMVDDSIDTKPMDQHLYDDSPK
                     NNLQDNSNNNSNSFYLANKPNPLTPVEIQQLSGKWQKNLASSIQLAQQAGKLNGEFIK
                     LINFFLQPQFSWQSLLSQYMFSFVRDDFSYARPSRRSGNAILPSLRSSQINITVAIDT
                     SGSISQNEINEFIIEINAIKSNIRATITLIACDEKVSKELIWRFEVWDELIFPVSLVG
                     GGKGTNFNPVFDHVNTQEIASSVLIYFTDAKGKFPKYEPIYPVMWLIKGNKNVPWGHR
                     IQLN"
     misc_feature    complement(518227..518976)
                     /locus_tag="COSY_0494"
                     /note="Putative metallopeptidase domain; Region:
                     DUF2201_N; pfam13203"
                     /db_xref="CDD:221979"
     misc_feature    complement(517831..518211)
                     /locus_tag="COSY_0494"
                     /note="VWA-like domain (DUF2201); Region: DUF2201;
                     pfam09967"
                     /db_xref="CDD:220493"
     gene            complement(519093..520133)
                     /locus_tag="COSY_0495"
                     /db_xref="GeneID:5171962"
     CDS             complement(519093..520133)
                     /locus_tag="COSY_0495"
                     /note="Similar to MoxR-like ATPase."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219338.1"
                     /db_xref="GI:148244644"
                     /db_xref="GeneID:5171962"
                     /translation="MRPKEVSEILNKELTSVIQGYHTPVMLWGSPGIGKSQIIFQIAS
                     NNKVNIIDIRLSQMEPSDLRGIPFKNGNLVDWSVPSLLPDSKRHGEQGILFLDEITSA
                     PPTVSAAAYQLILDRCLGDYTVPKGWVIFAAGNRQGDRGITYSMPAPLANRFSHFELD
                     VNLDDWVTWAYKNNIDERIIGFLRYRPEYLFEFNSKHNPTAFPSPRTWEFVHRALKKF
                     GTDLSLFKQAASACVGKIAGVEITTFIKHISDFPNLDSIINGESVSIPEELDLQYVIC
                     AALVGRATSLKGSNHAKKAWGNILNFAKNFPRNELGVMLVLDMQRAIGEDIFTIPEFA
                     DWANTISNVMLD"
     misc_feature    complement(519666..520112)
                     /locus_tag="COSY_0495"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(519666..520064)
                     /locus_tag="COSY_0495"
                     /note="ATPases associated with a variety of cellular
                     activities; Region: AAA; smart00382"
                     /db_xref="CDD:214640"
     misc_feature    complement(520026..520049)
                     /locus_tag="COSY_0495"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(519729..519731,519843..519845,
                     520026..520046))
                     /locus_tag="COSY_0495"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(519840..519857)
                     /locus_tag="COSY_0495"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(519675..519677)
                     /locus_tag="COSY_0495"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     gene            520197..520475
                     /locus_tag="COSY_0496"
                     /db_xref="GeneID:5171906"
     CDS             520197..520475
                     /locus_tag="COSY_0496"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219339.1"
                     /db_xref="GI:148244645"
                     /db_xref="GeneID:5171906"
                     /translation="MITVNSTSETLFNFPCDYSIKIFGKNCEKFQNTICTIVERHTHK
                     LNPNKITKKHSSKGNYVSFSIRIIANSRIQLDSINQDLKNCNLVSYVL"
     misc_feature    520221..520472
                     /locus_tag="COSY_0496"
                     /note="Protein of unknown function (DUF493); Region:
                     DUF493; pfam04359"
                     /db_xref="CDD:218043"
     gene            520482..521096
                     /gene="lipB"
                     /locus_tag="COSY_0497"
                     /db_xref="GeneID:5172396"
     CDS             520482..521096
                     /gene="lipB"
                     /locus_tag="COSY_0497"
                     /EC_number="2.3.1.-"
                     /note="lipoyl/octanoyltransferase; catalyzes the transfer
                     of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto
                     lipoate-dependent enzymes like pyruvate dehydrogenase and
                     the glycine cleavage system H protein"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate-protein ligase B"
                     /protein_id="YP_001219340.1"
                     /db_xref="GI:148244646"
                     /db_xref="GeneID:5172396"
                     /translation="MRVINLGRQDYLNIWDKMKTFTNTRDKNTKDELWIVEHNPVFTQ
                     GVSSKPEHILSNTDIPIVQTDRGGQVTYHGPGQVIIYCLFDLKRLGMGVKRIIEIIEN
                     SIIDLLRTYTIKAHLKSGAPGVYIDNAKIAALGLRIKQSRIYHGLSLNIDMDLSPFIQ
                     INPCGYQNLKVTQLCDLTDSRDTLNIIAKKLSQILINYVSRNRH"
     misc_feature    520482..521093
                     /gene="lipB"
                     /locus_tag="COSY_0497"
                     /note="lipoate-protein ligase B; Provisional; Region:
                     PRK14342"
                     /db_xref="CDD:237681"
     gene            521074..522021
                     /gene="lipA"
                     /locus_tag="COSY_0498"
                     /db_xref="GeneID:5172553"
     CDS             521074..522021
                     /gene="lipA"
                     /locus_tag="COSY_0498"
                     /EC_number="2.8.1.-"
                     /note="catalyzes the radical-mediated insertion of two
                     sulfur atoms into an acyl carrier protein (ACP) bound to
                     an octanoyl group to produce a lipoyl group"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="YP_001219341.1"
                     /db_xref="GI:148244647"
                     /db_xref="GeneID:5172553"
                     /translation="MFQEIDIKSLKGKSKVARLRIKPDVNRTVIRKPKWIRTKHIFGS
                     KVDQLKSTLRAQKLFTVCEEAQCPNLVECFNHGTATFMIMGQICTRRCPFCDVAHGKP
                     RTLDIDEPKHLADTIKKMRLKYVVITSVDRDDLHDGGVQHFKMCIDNIRLSTPKVKIE
                     ILTPDFKGRIDKALKVFKSCPPDVFNHNLETVPSLYPKVRPGANYEYSLKLLQKFKQQ
                     HPLVISKSGLMLGVGESEKQVINVLKDLRRHNVDMLTIGQYLQPSKYHLAVETYIHPN
                     QFDKYRKIALKLGFIRVASGPMVRSSYHANLQIKGKLII"
     misc_feature    521149..522006
                     /gene="lipA"
                     /locus_tag="COSY_0498"
                     /note="lipoyl synthase; Provisional; Region: PRK05481"
                     /db_xref="CDD:235493"
     gene            complement(522046..525492)
                     /locus_tag="COSY_0499"
                     /db_xref="GeneID:5172355"
     CDS             complement(522046..525492)
                     /locus_tag="COSY_0499"
                     /note="acriflavin resistance protein AcrB/AcrD/AcrF
                     family. hydrophobe/amphiphile efflux-1 (HAE1) family in
                     resistance-nodulation-cell division (RND) superfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux system"
                     /protein_id="YP_001219342.1"
                     /db_xref="GI:148244648"
                     /db_xref="GeneID:5172355"
                     /translation="MTNKSHVDQVKIDKVNRKFEMGIAGKLTKAFITSSLSIIIFFAM
                     LGAGIIGLISTPRQEDPQISVPLIDLFVEYPGASSKEVSNIIIKPLERLMSNILGVKH
                     VYSVSDKSKGVITVEFDVGQEMNTSIIKVRDKMLSNLEFMPPGAKQPLIKPKEIDDVP
                     IINLTLWSKSLDDGQLRSLGLELLQQLAKVKDTNNGFVVGGRKEIFHIDAYPGRLAGH
                     DISIQQIASTIGNANVRGHTGNIELNGLKMEVYSGDFFSKVEDIENLVITVNDGKPIY
                     VRDVADVYYAPEDAEHMVNYYTGKANKTEKKATAEQAITIAIAKKYGTNGVEVAENIL
                     AKVEELKGKLIPDNVEISVTRDYGKSAKDKVNVLIKKLFIATGAVTLLVWFALGIRPA
                     IVVTLVIPVVLLMTIFSAWILGMTIDRVSLFALIFSIGILVDDAIVVTENIYRRWLID
                     NKITIGTAIDAVREVGNPTILATFTVVAALVPMAAVSGMMGPYMAPIPILGSVAMMFS
                     LFAAFVFTPYFIMIFVPPLNVLHKMHKKEEKEAKVMFTFFHSTISKLFNIKIYGWGFL
                     IGLIVAFFMSISMFYTTLVPVKMLPLDNKSEFGVILNMPDGTALANTASTLHKMAQVL
                     RNVPEVVAIQSYSGTAKPFDFNGLVRHYYLRQSPSEGELQIQLVEKSERARSSHEIAL
                     EARTLIKQIVEDVGANYAVIEMPPGPPVLSPVVAEVYGPDKETRRKLANDLTELFKES
                     GTMTDVDNLIRDKYPVIDFQVDTAKASRFGVSVMTIKETLSMAMSSFNVGTIRLKNAL
                     EPSRICLQIPLSKRSQLSYLTQLPVPSQHGGLIPISELGSFSYKKQDDLIFHKDLADI
                     EYVLGEPKGRLSAPIYAMLGVDDLLLKYQTIDGKQLQGEYLGPPKDQTIPSFEWTGEW
                     TVTYETFRDMGSTFAIALVVIYMLVVWQFGSFIIPAVIMAPIPLTLLGIVPGHWLLDA
                     EFTATSMIGWIALAGIIVRNSILLVDFTVQEYAKGIPFFDAIINSCSSRTRPIMITAF
                     ALVGGSSVILSDPIFQGMAISLLFGVLISTILTLIVIPLGTLSAGEATCRNIAVNMGL
                     LPENKDADSKYNVEEPKSEKENKDPKEWIKTVLGRKNKVKLSSEELGINKLVKKTDKN
                     NL"
     misc_feature    complement(522328..525366)
                     /locus_tag="COSY_0499"
                     /note="Cation/multidrug efflux pump [Defense mechanisms];
                     Region: AcrB; COG0841"
                     /db_xref="CDD:223911"
     gene            complement(525499..526674)
                     /locus_tag="COSY_0500"
                     /db_xref="GeneID:5171825"
     CDS             complement(525499..526674)
                     /locus_tag="COSY_0500"
                     /note="acriflavin resistance protein AcrA/AcrE family.
                     hydrophobe/amphiphile efflux-1 (HAE1) family in
                     resistance-nodulation-cell division (RND) superfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux system"
                     /protein_id="YP_001219343.1"
                     /db_xref="GI:148244649"
                     /db_xref="GeneID:5171825"
                     /translation="MHTLILLFTSIVLMSSLPSKAQITSLNMSLKGSTKQNINNFESV
                     YNIQAVRGISLDKRALLGGSVISSSRVNLVAQVSGDVLNIKGQEGDMFKKGAILVTLE
                     QESIQAQRDSAYAAIASASEALRNAGVQYSQSIVSPNSGGMFGSVPGMFSMFTDPMLK
                     ISGQGNPDFDKFANRTSRYTNYQQAKNKLKQAELHLKQAESRLKDANVSAPFDGVIVA
                     KNINKGDVVQPGQILIKFANIKNLQVEVNVPSRLVRSLKLNKTYRIKLDIANIVVDAK
                     LSQIYPIADNVKHSVKVKFDLPANVPVLSGAYAEVEIFETDSGVLTPVIPEIAIMWRS
                     SLPSVFVVNSLTNKTELRFIRLGEQVGKNKKSVLSGLKIGERIVSNPNILMVSGMGI"
     misc_feature    complement(525508..526536)
                     /locus_tag="COSY_0500"
                     /note="RND family efflux transporter, MFP subunit; Region:
                     RND_mfp; TIGR01730"
                     /db_xref="CDD:233547"
     misc_feature    complement(525760..526047)
                     /locus_tag="COSY_0500"
                     /note="HlyD family secretion protein; Region: HlyD_3;
                     pfam13437"
                     /db_xref="CDD:222128"
     gene            526875..527873
                     /gene="pdxA"
                     /locus_tag="COSY_0501"
                     /db_xref="GeneID:5172504"
     CDS             526875..527873
                     /gene="pdxA"
                     /locus_tag="COSY_0501"
                     /EC_number="1.1.1.262"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase"
                     /protein_id="YP_001219344.1"
                     /db_xref="GI:148244650"
                     /db_xref="GeneID:5172504"
                     /translation="MTTIAFTVGEPSGIGPDLAVIYAQIKSNKNLLLFTDPDVLLNRA
                     KQLNLNIKIIEAEQAGSNYELAVYPIKVNTHVECGILNKDNAQYVLNTLDCATEYCLN
                     SRCDALVTGPIHKGIINQAGINFTGHTEYLANLSNIDKTVMMLATNGLRVALATTHMP
                     LSDVPQNITTQSLKKTISIIHQFLLNNGVNTPKIVVCGLNPHAGENGYLGMEEIEIIN
                     PLIKELNSQGYNLVGSIPADTAFTPNSLTGVDCVLSMYHDQGLPVLKTLGFKKAVNIT
                     LGLPFIRTSVDHGSALNLAGTGNISLGSLNTAINYAQMLVINHKKFKPTKVVSLDT"
     misc_feature    526884..527822
                     /gene="pdxA"
                     /locus_tag="COSY_0501"
                     /note="4-hydroxythreonine-4-phosphate dehydrogenase;
                     Region: pdxA; TIGR00557"
                     /db_xref="CDD:233023"
     misc_feature    526884..527810
                     /gene="pdxA"
                     /locus_tag="COSY_0501"
                     /note="4-hydroxythreonine-4-phosphate dehydrogenase;
                     Validated; Region: pdxA; PRK03743"
                     /db_xref="CDD:179641"
     gene            527854..528618
                     /gene="ksgA"
                     /locus_tag="COSY_0502"
                     /db_xref="GeneID:5171874"
     CDS             527854..528618
                     /gene="ksgA"
                     /locus_tag="COSY_0502"
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyladenosine transferase"
                     /protein_id="YP_001219345.1"
                     /db_xref="GI:148244651"
                     /db_xref="GeneID:5171874"
                     /translation="MYLLIHKARKRFGQNFLIDNRIIDRIIATISPKRNDNLLEIGPG
                     QGAITIPLLNYVNQLNVIEIDLNLISILESLEYSHLIIYQGDVLKFDLNILPMPIRII
                     GNLPYNISSSILFHLIENLDKIQDITVMLQKEVVERMGANSGSKVYGRLSVMMQTFFN
                     INMIFTVPPESFNPVPRVDSAIVYLKPLAQPKTKNIKVFEKVVKLAFSQRRKMLRNSL
                     KYVLTQKQTDIDLSRRAEMLTVDDFITLTQDYEKQH"
     misc_feature    527869..528615
                     /gene="ksgA"
                     /locus_tag="COSY_0502"
                     /note="16S ribosomal RNA methyltransferase KsgA/Dim1
                     family protein; Reviewed; Region: ksgA; PRK00274"
                     /db_xref="CDD:234708"
     misc_feature    527872..528615
                     /gene="ksgA"
                     /locus_tag="COSY_0502"
                     /note="Dimethyladenosine transferase (rRNA methylation)
                     [Translation, ribosomal structure and biogenesis]; Region:
                     KsgA; COG0030"
                     /db_xref="CDD:223109"
     gene            528602..528973
                     /gene="apaG"
                     /locus_tag="COSY_0503"
                     /db_xref="GeneID:5172699"
     CDS             528602..528973
                     /gene="apaG"
                     /locus_tag="COSY_0503"
                     /note="protein associated with Co2+ and Mg2+ efflux"
                     /codon_start=1
                     /transl_table=11
                     /product="ApaG"
                     /protein_id="YP_001219346.1"
                     /db_xref="GI:148244652"
                     /db_xref="GeneID:5172699"
                     /translation="MKNNIEIKIKVTYLESQSDIYANQYIYTYTITITNRGNVGVQLL
                     TRHWRIKDETGHTEDVIGKGVIGQQPHLSPKESFQYSSGSIIKTQTGSMKGSYGMIND
                     RGERFNVKIPEFILSKPYTLH"
     misc_feature    528602..528970
                     /gene="apaG"
                     /locus_tag="COSY_0503"
                     /note="CO2+/MG2+ efflux protein ApaG; Reviewed; Region:
                     apaG; PRK05461"
                     /db_xref="CDD:180098"
     gene            528973..529770
                     /gene="apaH"
                     /locus_tag="COSY_0504"
                     /db_xref="GeneID:5171951"
     CDS             528973..529770
                     /gene="apaH"
                     /locus_tag="COSY_0504"
                     /EC_number="3.6.1.41"
                     /note="hydrolyzes P(1),P(4)-bis(5'-adenosyl)
                     tetraphosphate to form 2 ADP"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenosine tetraphosphatase"
                     /protein_id="YP_001219347.1"
                     /db_xref="GI:148244653"
                     /db_xref="GeneID:5171951"
                     /translation="MSDYLIGDVQGCFDSLQTLLKKIKFSSDKDRLFFLGDVVNRGKQ
                     SLATLRFIKDLKSNALMVLGNHDFHLLACTLGRKNPNKKDTFTDIINAHDANLLLDFL
                     KNQPLAIKHKGVLMIHAGVPPSWDIDRTLKQSRQVQKHLQSVNVSQFLNKMYGNKPNI
                     WSKDLTELEQCKYTINALMRLRFCKSNDQLEFSHKMNYTHPPKGFKAWFMHKNRLLKN
                     TDIFFGHWSSLSGVNQTHIYSMDHGCIWHGHLSAIRLKDKRIFSVSC"
     misc_feature    528973..529767
                     /gene="apaH"
                     /locus_tag="COSY_0504"
                     /note="diadenosine tetraphosphatase; Reviewed; Region:
                     apaH; PRK00166"
                     /db_xref="CDD:234673"
     misc_feature    528979..529737
                     /gene="apaH"
                     /locus_tag="COSY_0504"
                     /note="Escherichia coli ApaH and related proteins,
                     metallophosphatase domain; Region: MPP_ApaH; cd07422"
                     /db_xref="CDD:163665"
     misc_feature    order(528994..528996,529000..529002,529081..529083,
                     529090..529095,529165..529170,529324..529326,
                     529645..529647,529693..529695,529708..529710)
                     /gene="apaH"
                     /locus_tag="COSY_0504"
                     /note="active site"
                     /db_xref="CDD:163665"
     misc_feature    order(528994..528996,529000..529002,529081..529083,
                     529165..529167,529324..529326,529645..529647)
                     /gene="apaH"
                     /locus_tag="COSY_0504"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163665"
     gene            complement(529767..530582)
                     /gene="dapF"
                     /locus_tag="COSY_0505"
                     /db_xref="GeneID:5172099"
     CDS             complement(529767..530582)
                     /gene="dapF"
                     /locus_tag="COSY_0505"
                     /EC_number="5.1.1.7"
                     /note="involved in lysine biosynthesis; DAP epimerase;
                     produces DL-diaminopimelate from LL-diaminopimelate"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="YP_001219348.1"
                     /db_xref="GI:148244654"
                     /db_xref="GeneID:5172099"
                     /translation="MLINFTKMHGLGNDFMVVDNLAGDITFNAKKITNLANRAFGIGF
                     DQLLVVETSNIRGVDFRYVIYNSNGSEVEQCGNGARCFARFVNYKNLTHSNPITVKTR
                     SNIISLHLNDDNTVCVDMGKPSFNPADIPLLVPQQSEYYQIEGFDLGAISIGNPHCVM
                     LVKDVNTIDVNTIALKIQQSELLPNQANIGFMQILNTHEINLRVYERGSEETLACGSG
                     ACAAVAYGVEQGLLKKNVVVHLSGGDALIEYTQGGHIFLSGPAQFVFEGQVEI"
     misc_feature    complement(529770..530582)
                     /gene="dapF"
                     /locus_tag="COSY_0505"
                     /note="diaminopimelate epimerase; Provisional; Region:
                     dapF; PRK00450"
                     /db_xref="CDD:234768"
     misc_feature    complement(530208..530570)
                     /gene="dapF"
                     /locus_tag="COSY_0505"
                     /note="Diaminopimelate epimerase; Region: DAP_epimerase;
                     pfam01678"
                     /db_xref="CDD:216645"
     misc_feature    complement(529791..530135)
                     /gene="dapF"
                     /locus_tag="COSY_0505"
                     /note="Diaminopimelate epimerase; Region: DAP_epimerase;
                     pfam01678"
                     /db_xref="CDD:216645"
     gene            532101..533438
                     /locus_tag="COSY_0506"
                     /db_xref="GeneID:5172204"
     CDS             532101..533438
                     /locus_tag="COSY_0506"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-associated Zn-dependent protease"
                     /protein_id="YP_001219349.1"
                     /db_xref="GI:148244655"
                     /db_xref="GeneID:5172204"
                     /translation="MVFIYALGFFLITTSILTTVHELGHFLVAKKFNVKVLRFSIGFG
                     KILTSFKYGETQYTLCALPLGGFIKMLDENETSVERSEKHRAFNQQNVYIRIMIIVAG
                     PIANFILAIILYTVVFAIGVTGVKPIVGTLETPSIAQQSGIKKGDQLLSINGISTPTI
                     SEFSMSFIQSLNKTPLYINVISDTSNLRKLKLNLSGDFLSNPEQGIDRYLGFKFAMPK
                     LEAIIDQIMPNSAASIAGLQINDKILSENHTHIDSWSDFVNTVQNNPNKKINLRVERD
                     DNIINITLIPKIENGLVKAGVNVLIPNNYLDEWLVLVKKNIFDAFIEANNKVYQLILL
                     NLRMIKKMIIGNVSLDQINGPISIANYAGKSAQVGFVTFLSFLAIISIGLGLLNLLPI
                     PLLDGGHLFFYLIELIKGSAVSRSFQQVLTRFGLFVIILITVVALYNDLSRLL"
     misc_feature    532101..533432
                     /locus_tag="COSY_0506"
                     /note="zinc metallopeptidase RseP; Provisional; Region:
                     PRK10779"
                     /db_xref="CDD:182723"
     misc_feature    532125..>532460
                     /locus_tag="COSY_0506"
                     /note="RseP-like Site-2 proteases (S2P), zinc
                     metalloproteases (MEROPS family M50A), cleave
                     transmembrane domains of substrate proteins, regulating
                     intramembrane proteolysis (RIP) of diverse signal
                     transduction mechanisms. In Escherichia coli, the S2P
                     homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163"
                     /db_xref="CDD:100084"
     misc_feature    order(532161..532166,532173..532175)
                     /locus_tag="COSY_0506"
                     /note="active site"
                     /db_xref="CDD:100084"
     misc_feature    532440..532649
                     /locus_tag="COSY_0506"
                     /note="PDZ domain of bacterial and plant zinc
                     metalloprotases, presumably membrane-associated or
                     integral membrane proteases, which may be involved in
                     signalling and regulatory mechanisms. May be responsible
                     for substrate recognition and/or binding, as most PDZ...;
                     Region: PDZ_metalloprotease; cd00989"
                     /db_xref="CDD:238489"
     misc_feature    order(532443..532454,532458..532460,532587..532592,
                     532602..532607)
                     /locus_tag="COSY_0506"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238489"
     misc_feature    532728..532958
                     /locus_tag="COSY_0506"
                     /note="PDZ domain of bacterial and plant zinc
                     metalloprotases, presumably membrane-associated or
                     integral membrane proteases, which may be involved in
                     signalling and regulatory mechanisms. May be responsible
                     for substrate recognition and/or binding, as most PDZ...;
                     Region: PDZ_metalloprotease; cd00989"
                     /db_xref="CDD:238489"
     misc_feature    order(532728..532736,532740..532742,532869..532874,
                     532881..532886)
                     /locus_tag="COSY_0506"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238489"
     misc_feature    <533286..533429
                     /locus_tag="COSY_0506"
                     /note="Site-2 protease (S2P) class of zinc
                     metalloproteases (MEROPS family M50) cleaves transmembrane
                     domains of substrate proteins, regulating intramembrane
                     proteolysis (RIP) of diverse signal transduction
                     mechanisms. Members of this family use proteolytic...;
                     Region: S2P-M50; cl10020"
                     /db_xref="CDD:245232"
     gene            533454..535745
                     /locus_tag="COSY_0507"
                     /db_xref="GeneID:5171886"
     CDS             533454..535745
                     /locus_tag="COSY_0507"
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen family protein"
                     /protein_id="YP_001219350.1"
                     /db_xref="GI:148244656"
                     /db_xref="GeneID:5171886"
                     /translation="MRKIITKLILVASILVCSIASATSIKSIEILGLNVISRDSVLSY
                     LPVEIGDDYNSQVSNQIIRSLYKTNFFKDIEVSQEAKILKIKLTENPHIKYINVTNHS
                     NKVIEEKPLNKILKNMGFSQGKIFNKRQFDKLITQLKDTYISKGYYGINIDKNIDIDT
                     QNRVSIKLDINEGKVAKISSMKIIGNHVFNEIDLLNLFEIGQSDFFIINFFTEKDHHS
                     KIALDVGIESMKSLYTNAGYFNFKIDKIKTNLSENKQNIDITIQISEGSKYKIGSIKF
                     TGNLLSHPIEKLRKLLSFNKNDIFNHKKMMQGLQNINNVFTNQGYAFSDVKVRISENT
                     STHTIDLNIDITPNRKVYINRITIIGNTRTKDEVIRREIGIYEGSLYSSTELNESIKK
                     IKRLGFFSEVKIQVSKLKDIEDKINLYFSVVETQTGTFSIGFSHSNNTGASLNLGVQE
                     RNFLGTGNTLSLSLSNSKATRDVSFYFSNPYFTQNKHSISYGIFSKKLDASELELDEY
                     KIDENGFSLGYSVPITKATRIGANLRASKRYITCGLTFSDNDHEPTQCAKKDKTELKL
                     GLNWSNNTLNDFNFPTKGQQSNLNFSLTLPIADFRYYKLDASHKSYYPLKNDLTFSLR
                     GNLGFAQGYDGKEFPFFKRYYGGGSSSVRGFDFNSLGVKYLNSNKAKGGELSFLTSAS
                     IILPIKLIDNNKNMRISVFVDLGSVSEKASNFDLEELRLSTGIAFSWLTPIGPLGFYA
                     ARPLIKKLGDKTKTFDFTLGTSF"
     misc_feature    533526..535742
                     /locus_tag="COSY_0507"
                     /note="outer membrane protein assembly complex, YaeT
                     protein; Region: OM_YaeT; TIGR03303"
                     /db_xref="CDD:234165"
     misc_feature    533724..533972
                     /locus_tag="COSY_0507"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:219346"
     misc_feature    533979..534251
                     /locus_tag="COSY_0507"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:219346"
     misc_feature    534258..534497
                     /locus_tag="COSY_0507"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:219346"
     misc_feature    534546..534725
                     /locus_tag="COSY_0507"
                     /note="Surface antigen variable number repeat; Region:
                     Surf_Ag_VNR; pfam07244"
                     /db_xref="CDD:219346"
     misc_feature    534864..535742
                     /locus_tag="COSY_0507"
                     /note="Surface antigen; Region: Bac_surface_Ag; pfam01103"
                     /db_xref="CDD:216300"
     gene            535784..536782
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /db_xref="GeneID:5172164"
     CDS             535784..536782
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-[3-hydroxymyristoyl] glucosamine
                     N-acyltransferase"
                     /protein_id="YP_001219351.1"
                     /db_xref="GI:148244657"
                     /db_xref="GeneID:5172164"
                     /translation="MHTLGDIAKTINAKLVGDSNVEITGVASSLYANQTQLTYIINSK
                     YKQTLIHSKAGVVILNKDLLRICPTNALVVDNVYLAFAKATHLFKKQNVCYQGIHPSA
                     KINNAKIAPNCIIGRNVSIGNHCIIASNVVIEDNVTIGNYALIQPNVSILQGCSIGDN
                     IVISPGVVIGSEGFGNAQDQQKHWHSIAHLGYVVIGNNVSIGANTTIDRGTIEDTQIH
                     NGVRIDNLVHIAHNVIIEQDSAIAATVTIGGSCKLGKRCMVGGGATITSHVNLADDII
                     ITGASTVDKNLSEQGHYTGFTSISKHQKWKKIQVWLLNLDKIVHYLNIKLKKLKEK"
     misc_feature    535790..536779
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /note="UDP-3-O-[3-hydroxymyristoyl] glucosamine
                     N-acyltransferase; Provisional; Region: lpxD; PRK00892"
                     /db_xref="CDD:234858"
     misc_feature    535838..536047
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /note="UDP-3-O-[3-hydroxymyristoyl] glucosamine
                     N-acyltransferase, LpxD; Region: LpxD; pfam04613"
                     /db_xref="CDD:218175"
     misc_feature    order(535952..535954,535958..535960,536015..536017,
                     536027..536029,536105..536107,536120..536125,
                     536129..536131,536159..536161,536171..536173,
                     536174..536176,536180..536182)
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /note="putative trimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:100038"
     misc_feature    536084..536701
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /note="UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD):
                     The enzyme catalyzes the transfer of 3-hydroxymyristic
                     acid or 3-hydroxy-arachidic acid, depending on the
                     organism, from the acyl carrier protein (ACP) to
                     UDP-3-O-acyl-glucosamine to produce UDP-2; Region:
                     LbH_LpxD; cd03352"
                     /db_xref="CDD:100043"
     misc_feature    order(536105..536107,536111..536116,536129..536131,
                     536165..536167,536180..536182)
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100038"
     misc_feature    order(536117..536119,536129..536134,536186..536188,
                     536225..536227,536231..536233,536237..536239,
                     536273..536275,536279..536281,536297..536299,
                     536303..536305,536339..536347,536381..536383,
                     536393..536395,536399..536401,536405..536407,
                     536414..536422,536447..536449,536453..536461,
                     536465..536467,536477..536479,536495..536497,
                     536501..536503,536513..536521,536549..536551,
                     536567..536575,536585..536587,536621..536629,
                     536681..536683,536693..536695)
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100043"
     misc_feature    order(536303..536311,536453..536455,536465..536467,
                     536474..536479,536507..536512,536525..536533,
                     536582..536587,536618..536620)
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /note="active site"
                     /db_xref="CDD:100043"
     misc_feature    order(536303..536311,536474..536479,536528..536533,
                     536582..536587)
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /note="UDP-GlcNAc binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100043"
     misc_feature    order(536453..536455,536465..536467,536507..536512,
                     536525..536527,536618..536620)
                     /gene="lpxD"
                     /locus_tag="COSY_0508"
                     /note="lipid binding site [chemical binding];
                     lipid-binding site"
                     /db_xref="CDD:100043"
     gene            536784..537227
                     /gene="fabZ"
                     /locus_tag="COSY_0509"
                     /db_xref="GeneID:5172260"
     CDS             536784..537227
                     /gene="fabZ"
                     /locus_tag="COSY_0509"
                     /EC_number="4.2.1.-"
                     /note="in Pseudomonas aeruginosa this enzyme is a trimer
                     of dimers; essential for membrane formation; performs
                     third step of type II fatty acid biosynthesis; catalyzes
                     dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP"
                     /codon_start=1
                     /transl_table=11
                     /product="(3R)-hydroxymyristoyl-ACP dehydratase"
                     /protein_id="YP_001219352.1"
                     /db_xref="GI:148244658"
                     /db_xref="GeneID:5172260"
                     /translation="MEMNIQDVKNYLPHRYPFLLIDRVLELEVGKSIVALKNVTFNEP
                     QFIGHFPDQPIMPGVMIVEALAQATGILAFKAEVSKPTNGQIYMLVGIDKVRFKRMVE
                     PGDQLRLEVGIVTVKRGIWKFKCKATVDSQTITSAELMCTQKATD"
     misc_feature    536817..537206
                     /gene="fabZ"
                     /locus_tag="COSY_0509"
                     /note="FabZ is a 17kD beta-hydroxyacyl-acyl carrier
                     protein (ACP) dehydratase that primarily catalyzes the
                     dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP,
                     the third step in the elongation phase of the bacterial/
                     plastid, type II, fatty-acid...; Region: FabZ; cd01288"
                     /db_xref="CDD:238615"
     gene            537253..538044
                     /gene="lpxA"
                     /locus_tag="COSY_0510"
                     /db_xref="GeneID:5172514"
     CDS             537253..538044
                     /gene="lpxA"
                     /locus_tag="COSY_0510"
                     /EC_number="2.3.1.129"
                     /note="acyl-[acyl-carrier-protein]--UDP-N-
                     acetylglucosamine O-acyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine acyltransferase"
                     /protein_id="YP_001219353.1"
                     /db_xref="GI:148244659"
                     /db_xref="GeneID:5172514"
                     /translation="MTIDSSAIVDPSAKIHKNAEIYAYVIIGANVEIDSGTIVEAHTV
                     IQGPTRIGKNNHIYSFASIGGDPQDITYAEGQESSLIIGNDNLIREFCTINRGTEKEN
                     SITRVGSNNMLMAYVHIAHDCQVGNHIIMSNNASLAGHVRIYDWAILGGFTLAKQFCM
                     IGMHTYVGMGCQINKDIPAYMVASGVQTRVRSINSEGMRRRGFSPNAIAAIKRAFKAV
                     YRESGLLDQSLKELEQSESDHPEVVQFVNCIRSSKVGIMRGPTEE"
     misc_feature    537253..538029
                     /gene="lpxA"
                     /locus_tag="COSY_0510"
                     /note="UDP-N-acetylglucosamine acyltransferase;
                     Provisional; Region: PRK05289"
                     /db_xref="CDD:235390"
     misc_feature    537259..538020
                     /gene="lpxA"
                     /locus_tag="COSY_0510"
                     /note="UDP-N-acetylglucosamine O-acyltransferase
                     (UDP-GlcNAc acyltransferase): Proteins in this family
                     catalyze the transfer of (R)-3-hydroxymyristic acid from
                     its acyl carrier protein thioester to UDP-GlcNAc. It is
                     the first enzyme in the lipid A biosynthetic...; Region:
                     LbH_UDP-GlcNAc_AT; cd03351"
                     /db_xref="CDD:100042"
     misc_feature    order(537454..537456,537463..537465,537535..537537,
                     537604..537606,537613..537615,537670..537672,
                     537718..537723,537757..537759,537832..537834,
                     537850..537855)
                     /gene="lpxA"
                     /locus_tag="COSY_0510"
                     /note="active site"
                     /db_xref="CDD:100042"
     gene            538062..539588
                     /gene="mviN"
                     /locus_tag="COSY_0511"
                     /db_xref="GeneID:5172281"
     CDS             538062..539588
                     /gene="mviN"
                     /locus_tag="COSY_0511"
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor MviN"
                     /protein_id="YP_001219354.1"
                     /db_xref="GI:148244660"
                     /db_xref="GeneID:5172281"
                     /translation="MDKSFLKSSGIIIAMTFLSRILGLVRDYFIARYFGASGLTDAFW
                     VAFRIPNFLRRLFGEGALSQAFMPILADAKANNTQIEVQNIINHIATKLLFVLIAITL
                     ITVIISPIIIFMFAWGFYFSPDLIQFNLASDMLRITFPYLLFISLTALSGAILNIYNH
                     FAVPAFTPVLLNISIILSSIYLSKHLNTPIMALAWGVFFGGVAQLLFQIPFLIKIKKL
                     PKLVLGNHQAVETLKKHMLPALFSVSVSQINLLVDTMIASLLVSGSISWLYYSDRLLE
                     LPLALIGITLATVSLAKLSHHFTDKNHEKFLQTIDNALTIGLLLGLPACVGLILLAKP
                     LIITLFQYDQFDAFAALQSSLSLMAYGSGLMAFIFVKVLAPIFLSIGDTKTPVKAGII
                     AMVSNIFLNIILGFYFAHVGLAIATSISALINASLLYFYLNKQSIFNISKNLYQTFFK
                     ALVSSFIMAIFILIFKSEAELYLRASVNSRIILLGTTIVLSSIIYFSSLKLLNIGVQK
                     "
     misc_feature    538062..539567
                     /gene="mviN"
                     /locus_tag="COSY_0511"
                     /note="Uncharacterized membrane protein, putative
                     virulence factor [General function prediction only];
                     Region: MviN; COG0728"
                     /db_xref="CDD:223800"
     misc_feature    538101..539366
                     /gene="mviN"
                     /locus_tag="COSY_0511"
                     /note="MurJ/MviN, a subfamily of the multidrug and toxic
                     compound extrusion (MATE)-like proteins; Region:
                     MATE_MurJ_like; cd13123"
                     /db_xref="CDD:240528"
     gene            539588..539857
                     /locus_tag="COSY_0512"
                     /db_xref="GeneID:5172019"
     CDS             539588..539857
                     /locus_tag="COSY_0512"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219355.1"
                     /db_xref="GI:148244661"
                     /db_xref="GeneID:5172019"
                     /translation="MNIVKCIKLNQKLEALDRAPYPGELGKKILNNISKQGWKLWLEH
                     QTMLINENNLNLMDSNAQNYLKEQMEKFFFSKEGADKIKGYSPDE"
     misc_feature    539588..539854
                     /locus_tag="COSY_0512"
                     /note="oxidative damage protection protein; Provisional;
                     Region: PRK05408"
                     /db_xref="CDD:180059"
     gene            539850..540461
                     /gene="gmk"
                     /locus_tag="COSY_0513"
                     /db_xref="GeneID:5171929"
     CDS             539850..540461
                     /gene="gmk"
                     /locus_tag="COSY_0513"
                     /EC_number="2.7.4.8"
                     /note="Essential for recycling GMP and indirectly, cGMP"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="YP_001219356.1"
                     /db_xref="GI:148244662"
                     /db_xref="GeneID:5171929"
                     /translation="MNNGVLFIISAPSGCGKTSLVKALIKKVENLCVSISHTTRQPRS
                     GEIQGKNYFFVSKDEFNKMKSSNNFIESTQVFDNNYGSSKQSVQDLLNSGFDVILEID
                     WRGFRQIKQTFSHSVGIFILPPSKVALEERLTNRGQDNKGIINRRMHDAVSEMQHFNE
                     FNYLVINDNFDVALNNLSTIVHAERLTLAQQSNKYQNLLKTLI"
     misc_feature    539850..540410
                     /gene="gmk"
                     /locus_tag="COSY_0513"
                     /note="Guanylate kinase [Nucleotide transport and
                     metabolism]; Region: Gmk; COG0194"
                     /db_xref="CDD:223272"
     misc_feature    539865..540314
                     /gene="gmk"
                     /locus_tag="COSY_0513"
                     /note="Guanosine monophosphate kinase (GMPK, EC 2.7.4.8),
                     also known as guanylate kinase (GKase), catalyzes the
                     reversible phosphoryl transfer from adenosine triphosphate
                     (ATP) to guanosine monophosphate (GMP) to yield adenosine
                     diphosphate (ADP) and guanosine...; Region: GMPK; cd00071"
                     /db_xref="CDD:238026"
     misc_feature    order(539880..539882,539898..539900,539946..539948,
                     539967..539969,539976..539978,540003..540005,
                     540072..540074,540087..540089)
                     /gene="gmk"
                     /locus_tag="COSY_0513"
                     /note="catalytic site [active]"
                     /db_xref="CDD:238026"
     misc_feature    order(539880..539882,539898..539900)
                     /gene="gmk"
                     /locus_tag="COSY_0513"
                     /note="G-X2-G-X-G-K; other site"
                     /db_xref="CDD:238026"
     gene            540511..541344
                     /gene="rpoH"
                     /locus_tag="COSY_0514"
                     /db_xref="GeneID:5172044"
     CDS             540511..541344
                     /gene="rpoH"
                     /locus_tag="COSY_0514"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase sigma-32 factor"
                     /protein_id="YP_001219357.1"
                     /db_xref="GI:148244663"
                     /db_xref="GeneID:5172044"
                     /translation="MNQEFALSSTQKTSSLEVQKYPPILSSEEEHELAVQLYENHNLS
                     AARKLVLSHMRFVAFIAHSYKGYGLEQADLVQEGTIGLMKAVKRFNPHRNVRLASFAV
                     YWIRAEIHEFIFKNWKIVKVATTKAQRKLFFKLKQAKAHIYNSLNEEQADKIAKDLGV
                     RRKDVLEMESRLQFSDVTFEVFDEEDSHAPEQYLTNENIQTPEQLLLTDDSKKTQQQR
                     LYKALSSLDERSLDILQSRYLKEEKTTLYTLADKYSISKERVRQLETKAMQKLKSNLQ
                     E"
     misc_feature    540511..541341
                     /gene="rpoH"
                     /locus_tag="COSY_0514"
                     /note="RNA polymerase factor sigma-32; Reviewed; Region:
                     PRK06596"
                     /db_xref="CDD:235838"
     misc_feature    540655..540867
                     /gene="rpoH"
                     /locus_tag="COSY_0514"
                     /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542"
                     /db_xref="CDD:218138"
     misc_feature    541156..541326
                     /gene="rpoH"
                     /locus_tag="COSY_0514"
                     /note="Sigma70, region (SR) 4 refers to the most
                     C-terminal of four conserved domains found in Escherichia
                     coli (Ec) sigma70, the main housekeeping sigma, and
                     related sigma-factors (SFs). A SF is a dissociable subunit
                     of RNA polymerase, it directs bacterial or...; Region:
                     Sigma70_r4; cd06171"
                     /db_xref="CDD:100119"
     misc_feature    order(541189..541191,541219..541221,541243..541248,
                     541276..541278,541282..541287,541291..541299,
                     541303..541308,541312..541314)
                     /gene="rpoH"
                     /locus_tag="COSY_0514"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:100119"
     gene            541411..541698
                     /gene="groES"
                     /locus_tag="COSY_0515"
                     /db_xref="GeneID:5172442"
     CDS             541411..541698
                     /gene="groES"
                     /locus_tag="COSY_0515"
                     /note="10 kDa chaperonin; Cpn10; GroES; forms
                     homoheptameric ring; binds to one or both ends of the
                     GroEL double barrel in the presence of adenine nucleotides
                     capping it; folding of unfolded substrates initiates in a
                     GroEL-substrate bound and capped by GroES; release of the
                     folded substrate is dependent on ATP binding and
                     hydrolysis in the trans ring"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperonin GroES"
                     /protein_id="YP_001219358.1"
                     /db_xref="GI:148244664"
                     /db_xref="GeneID:5172442"
                     /translation="MNIRPLHDRVVVRRVEEKKTTSSGLIIPDSATEKPSEGVVVAVG
                     NGKKNDNGDTIALDVTIGNKVLFAQYAGTEIKVDGKKLLIMKEGDIVAVIK"
     misc_feature    541414..541692
                     /gene="groES"
                     /locus_tag="COSY_0515"
                     /note="Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10
                     cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase,
                     to assist the folding and assembly of proteins and is
                     found in eubacterial cytosol, as well as in the matrix of
                     mitochondria and chloroplasts. It...; Region: cpn10;
                     cd00320"
                     /db_xref="CDD:238197"
     misc_feature    order(541414..541416,541420..541422,541426..541428,
                     541435..541437,541516..541521,541582..541584,
                     541612..541614,541627..541629,541633..541635,
                     541681..541689)
                     /gene="groES"
                     /locus_tag="COSY_0515"
                     /note="oligomerisation interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238197"
     misc_feature    541462..541503
                     /gene="groES"
                     /locus_tag="COSY_0515"
                     /note="mobile loop; other site"
                     /db_xref="CDD:238197"
     misc_feature    order(541543..541545,541576..541578)
                     /gene="groES"
                     /locus_tag="COSY_0515"
                     /note="roof hairpin; other site"
                     /db_xref="CDD:238197"
     gene            541711..543354
                     /gene="groEL"
                     /locus_tag="COSY_0516"
                     /db_xref="GeneID:5171872"
     CDS             541711..543354
                     /gene="groEL"
                     /locus_tag="COSY_0516"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; many bacteria have multiple
                     copies of the groEL gene which are active under different
                     environmental conditions; the B.japonicum protein in this
                     cluster is expressed constitutively; in Rhodobacter,
                     Corynebacterium and Rhizobium this protein is essential
                     for growth"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="YP_001219359.1"
                     /db_xref="GI:148244665"
                     /db_xref="GeneID:5171872"
                     /translation="MSAKDIKFGPEARNLMLDGVNMLANAVKVTLGPKGRNVVLDKSF
                     GGPTITKDGVSVAQEITLEGKFENMGAQMVKEVASKTNDIAGDGTTTATVLAQALVTE
                     GVKSVAAGMNPMDLKRGIDKATEVAVNALHDFSQPCNDTKAIAQVGTISANSDVSVGD
                     IIADAMEKVGQAGVITVEEGSGFENELDVVEGMQFDRGYLSPYFVNNQDTMTADLESP
                     FVLLHDAKISNIRDLLPALEIVQKSSKALLIIAEDIDGEALATLVVNNMRGIVKVAAV
                     KAPGFGDRRKAILEDIAILTGSVVISEEVGLSLEKVTEEHLGTAKRIEIGKENTVIVD
                     GAGKKSNIDGRVNQIKAQIETTTSDYDKEKLLERLAKLSGGVAVIKVGAATEVAMKEK
                     KDHVDDALHATRAAVEEGVVPGGGVALVRTIKALDGLTGDNHDQNIGIDIAKRAMEAP
                     LRQIVTNGGGEASVVLNNVADGKDNYGYNATTEEYGDMLKMGILDPTKVVRAALQHAA
                     SISGLMITTEAMITDIPQDATPTASPDMGGMGGMGGGMM"
     misc_feature    541717..543306
                     /gene="groEL"
                     /locus_tag="COSY_0516"
                     /note="chaperonin GroEL; Reviewed; Region: groEL;
                     PRK12849"
                     /db_xref="CDD:237230"
     misc_feature    541720..543279
                     /gene="groEL"
                     /locus_tag="COSY_0516"
                     /note="GroEL_like type I chaperonin. Chaperonins are
                     involved in productive folding of proteins. They share a
                     common general morphology, a double toroid of 2 stacked
                     rings, each composed of 7-9 subunits. The symmetry of type
                     I is seven-fold and they are found...; Region: GroEL;
                     cd03344"
                     /db_xref="CDD:239460"
     misc_feature    order(541720..541722,541732..541734,541783..541785,
                     541816..541827,541831..541833,541846..541851,
                     541855..541857,541885..541887,541891..541893,
                     541915..541917,541927..541929,541936..541938,
                     542299..542301,542395..542397,542479..542481,
                     542860..542862,542866..542868,543085..543087,
                     543247..543249,543256..543276)
                     /gene="groEL"
                     /locus_tag="COSY_0516"
                     /note="ring oligomerisation interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239460"
     misc_feature    order(541801..541809,541969..541971,541981..541983,
                     542158..542160,542902..542904,542953..542955,
                     543070..543072,543187..543189,543193..543195)
                     /gene="groEL"
                     /locus_tag="COSY_0516"
                     /note="ATP/Mg binding site [chemical binding]; other site"
                     /db_xref="CDD:239460"
     misc_feature    order(542035..542037,543010..543012,543064..543066,
                     543091..543093,543097..543102,543109..543111)
                     /gene="groEL"
                     /locus_tag="COSY_0516"
                     /note="stacking interactions; other site"
                     /db_xref="CDD:239460"
     misc_feature    order(542131..542133,542266..542268,542287..542289,
                     542833..542835,542935..542940)
                     /gene="groEL"
                     /locus_tag="COSY_0516"
                     /note="hinge regions; other site"
                     /db_xref="CDD:239460"
     gene            543491..544732
                     /locus_tag="COSY_0517"
                     /db_xref="GeneID:5171877"
     CDS             543491..544732
                     /locus_tag="COSY_0517"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219360.1"
                     /db_xref="GI:148244666"
                     /db_xref="GeneID:5171877"
                     /translation="MQHKLIILIISFLGLQVQANLQSFVNSKTNIIIPPTKIDNISHS
                     NIDNLSSKECSVCHYDIYKQWTNSMHAKSTALKDPIHGLFYGVVVGNPKVEGIKTGKD
                     KDKYPVCLECHSPAAAKEKKTKLNAKNSFSEGVNCIACHSLTKYKRIKKKNDRVKLGI
                     KAYKYSSHQIQGPNGTNKKHKRFGEGGVANNPGLFKTSKACLGCHNQRNNSKEVPLCQ
                     TGGEIISAGGSTTCQSCHMPVIEGISNHTMIGGHSVEMVSKGLVMTIKTKKVSDMLYI
                     SVNATNLLPHNFPTGAPFRNFYITVTAQDYNDNILWQSSKTHPMIDDKKAMFMYIIGD
                     DNNKPTSPPKATKILGDTRLKPNETRILNYKIPSNDVSIVTAKAYYDLLLVPMKNKFS
                     SKLPKRLLESKEIAKAIVVIR"
     misc_feature    543647..543913
                     /locus_tag="COSY_0517"
                     /note="Cytochrome c554 and c-prime; Region:
                     Cytochrome_C554; pfam13435"
                     /db_xref="CDD:222126"
     gene            544813..546693
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /db_xref="GeneID:5172399"
     CDS             544813..546693
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /EC_number="5.99.1.-"
                     /note="decatenates newly replicated chromosomal DNA and
                     relaxes positive and negative DNA supercoiling"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="YP_001219361.1"
                     /db_xref="GI:148244667"
                     /db_xref="GeneID:5172399"
                     /translation="MNSYDSSSIEVLTGLEPVRKHPGMYTETECPNHLAQEVIDNSVD
                     EAIAGFASKINVVLYKNNSLSVEDDGRGMPVDIHPKEGKSGVEVILTKLHAGGKFSND
                     LYQFSGGLHGVGISVVNALSTLVEIWIKRDAKEHHITFSNGSKKTELKVTRKVSKYNT
                     GTIVKFKPDARFFDNIKFSATKLHNNLRSKAVLCPDLEINFYNEINEKTDKWIYKEGL
                     KDYLSKSLDGLDCLPTDPFVVNYKTNEQQLNCSVTWTQYNTNIIAESYVNLIPTISGT
                     HVNGLRSGLTEALKEFCEFRNLIPKNIKLTPDDVWQKISYVLSIKIMDPQFSGQTKKR
                     LSSRECASFVANIVKDTFSIWLNQHTSMAKEIAQLAIINAQIKLKTNKKVIRKKIFSG
                     PILPGKLSDCISTDLNQTEVFLVEGDSAGGSAKQARNKEYQAILPLRGKILNTWEINS
                     EQILANKEIHDISIAIGLEPNSEDLSNLRYGKICILADADSDGAHIATLICTLFMKHF
                     PKLVQEGHIFVAMPPLYRIDAGKQVYYALNNNERDTIIRKVKNENKRVKIQVQRFKGL
                     GEMNPSQLRETTMLSNTRHLIQLTSNNPLQIFKTMDMLLSKKRAADRKKWLEENGNLD
                     NA"
     misc_feature    544813..546684
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="DNA topoisomerase IV subunit B; Reviewed; Region:
                     PRK05559"
                     /db_xref="CDD:235501"
     misc_feature    544909..545205
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    order(544921..544923,544933..544935,544942..544944,
                     545008..545010,545014..545016,545020..545022,
                     545026..545031,545146..545157,545197..545199,
                     545203..545205)
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    544933..544935
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    order(545020..545022,545026..545028,545146..545148,
                     545152..545154)
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     misc_feature    545461..545949
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="TopoIIA_Trans_DNA_gyrase: Transducer domain, having
                     a ribosomal S5 domain 2-like fold, of the type found in
                     proteins of the type IIA family of DNA topoisomerases
                     similar to the B subunits of E. coli DNA gyrase and E.
                     coli Topoisomerase IV which are; Region:
                     TopoII_Trans_DNA_gyrase; cd00822"
                     /db_xref="CDD:238419"
     misc_feature    545614..545616
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="anchoring element; other site"
                     /db_xref="CDD:238419"
     misc_feature    order(545782..545784,545791..545796,545800..545802,
                     545935..545940)
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238419"
     misc_feature    order(545800..545802,545806..545808)
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238419"
     misc_feature    546040..546378
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM)
                     nucleotidyl transferase/hydrolase domain of the type found
                     in proteins of the type IIA family of DNA topoisomerases
                     similar to Saccharomyces cerevisiae Topoisomerase II.
                     TopoIIA enzymes cut both strands...; Region:
                     TOPRIM_TopoIIA_like; cd01030"
                     /db_xref="CDD:173780"
     misc_feature    order(546058..546063,546070..546072,546274..546276,
                     546280..546282,546286..546288)
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="active site"
                     /db_xref="CDD:173780"
     misc_feature    order(546058..546060,546274..546276)
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="putative metal-binding site [ion binding]; other
                     site"
                     /db_xref="CDD:173780"
     misc_feature    546481..546666
                     /gene="parE"
                     /locus_tag="COSY_0518"
                     /note="DNA gyrase B subunit, carboxyl terminus; Region:
                     DNA_gyraseB_C; pfam00986"
                     /db_xref="CDD:201537"
     gene            546686..547378
                     /gene="exsB"
                     /locus_tag="COSY_0519"
                     /db_xref="GeneID:5171880"
     CDS             546686..547378
                     /gene="exsB"
                     /locus_tag="COSY_0519"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-regulatory protein ExsB"
                     /protein_id="YP_001219362.1"
                     /db_xref="GI:148244668"
                     /db_xref="GeneID:5171880"
                     /translation="MLNAKHKIKAVILLSGGLDSTTTLAIAKSKKFECYSLSFDYGQK
                     QESELQSAKNIAKIFITSEHRVVKISLSGISKSALTNDNIDVPKFSQSNKIPITYVPA
                     RNTIFLSYALAWSEVLNCQHIFIGVNELDYSGYPDCRKSYIKAFEIMANLATKQGIEG
                     QKLTIHTPLIHLNKAQIIKKGLSLGIDYTLTTTCYQADKNGKACGICDACEYRKLGFK
                     EAKVPDQTRYQT"
     misc_feature    546710..547342
                     /gene="exsB"
                     /locus_tag="COSY_0519"
                     /note="ExsB is a transcription regulator related protein.
                     It is a subfamily of a Adenosine nucleotide binding
                     superfamily of proteins. This protein family is
                     represented by a single member in nearly every completed
                     large (&gt; 1000 genes) prokaryotic genome. In...; Region:
                     ExsB; cd01995"
                     /db_xref="CDD:238953"
     misc_feature    order(546722..546730,546734..546745,546809..546811,
                     546815..546817)
                     /gene="exsB"
                     /locus_tag="COSY_0519"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238953"
     gene            547487..547711
                     /gene="acpP"
                     /locus_tag="COSY_0520"
                     /db_xref="GeneID:5172481"
     CDS             547487..547711
                     /gene="acpP"
                     /locus_tag="COSY_0520"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="YP_001219363.1"
                     /db_xref="GI:148244669"
                     /db_xref="GeneID:5172481"
                     /translation="MSIEQRVKKVVAEQLDVSGDVDNNASFVDDLGADSLDTVELVMS
                     LEDEFECEIPDDQAENITNVQQAIDYVSNL"
     misc_feature    547487..547705
                     /gene="acpP"
                     /locus_tag="COSY_0520"
                     /note="acyl carrier protein; Provisional; Region: acpP;
                     PRK00982"
                     /db_xref="CDD:179197"
     gene            547790..549031
                     /gene="fabF"
                     /locus_tag="COSY_0521"
                     /db_xref="GeneID:5172491"
     CDS             547790..549031
                     /gene="fabF"
                     /locus_tag="COSY_0521"
                     /EC_number="2.3.1.41"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase I/II"
                     /protein_id="YP_001219364.1"
                     /db_xref="GI:148244670"
                     /db_xref="GeneID:5172491"
                     /translation="MSKRRVVITGMGIICPVGLSVSESWDNILKGYSGIASLTNINTK
                     GQSVTFGGSVKNFEVTDYLRPKDAKKMDTFIHYGMAASIQAIEDSGIEVTEKNACRIG
                     VAIGAGIGGLGTIERTADLFREKGAGRISPFFVPSSIINMISGNLSIKYGLKGPNFAI
                     TTACTTGTHNIGNASRLIEYNDADVMIAGGAEMSTTNCGLGGFAAARALSTRNDDPIS
                     ASRPWDKDRDGFVLGDGAGIIVLEEFEHAKARGAKIYAQVSGYGMSGDAYHITLPSKG
                     GEGAARCMQNAMNNSGINVDEINYINAHGTSTLVGDQAETDAVKLAFREQHAYNIVIS
                     STKSMTGHLLGASGGIEAIFTTLAIQDQVVPPTINIINQDPNCDLDYCANEAREMTIN
                     HAISNSFGFGGTNGSIVLSRI"
     misc_feature    547799..548974
                     /gene="fabF"
                     /locus_tag="COSY_0521"
                     /note="Beta-ketoacyl-acyl carrier protein (ACP) synthase
                     (KAS), type I and II. KASs are responsible for the
                     elongation steps in fatty acid biosynthesis. KASIII
                     catalyses the initial condensation and KAS I and II
                     catalyze further elongation steps by Claisen...; Region:
                     KAS_I_II; cd00834"
                     /db_xref="CDD:238430"
     misc_feature    547799..548974
                     /gene="fabF"
                     /locus_tag="COSY_0521"
                     /note="beta-ketoacyl-acyl-carrier-protein synthase II;
                     Region: fabF; TIGR03150"
                     /db_xref="CDD:200247"
     misc_feature    order(548111..548113,548132..548137,548147..548149,
                     548153..548158,548192..548194,548210..548212,
                     548222..548224,548234..548236,548252..548254,
                     548258..548260,548264..548272,548306..548308,
                     548315..548320,548327..548329,548390..548395,
                     548402..548407,548579..548593,548633..548635)
                     /gene="fabF"
                     /locus_tag="COSY_0521"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238430"
     misc_feature    order(548279..548281,548699..548701,548813..548815)
                     /gene="fabF"
                     /locus_tag="COSY_0521"
                     /note="active site"
                     /db_xref="CDD:238430"
     gene            complement(549089..549301)
                     /locus_tag="COSY_0522"
                     /db_xref="GeneID:5172494"
     CDS             complement(549089..549301)
                     /locus_tag="COSY_0522"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219365.1"
                     /db_xref="GI:148244671"
                     /db_xref="GeneID:5172494"
                     /translation="MIKFILSIIIILALIGGAIKFVATEESWSLVMNKGVALSSVQNG
                     AIAIYEFIEALISDANKIKIVDSTIK"
     gene            complement(549294..551228)
                     /gene="prlC"
                     /locus_tag="COSY_0523"
                     /db_xref="GeneID:5172290"
     CDS             complement(549294..551228)
                     /gene="prlC"
                     /locus_tag="COSY_0523"
                     /EC_number="3.4.24.70"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="YP_001219366.1"
                     /db_xref="GI:148244672"
                     /db_xref="GeneID:5172290"
                     /translation="MKPNFQPKNIVKTIERLTRNGLKIVKKASFGTNWESVVMPIDQM
                     KFELEKHISVNSHLNAVMFSDEFNQKYEETLPIITNFYSDVSTNKDLYQAYNSLRGVN
                     LNKQQQHIVKDVIKGFELSGVGLEGKNADRFKVIKEKLSLLSNEFSKNILKSTNEWKK
                     IVSKHELKGYSDNELVKIKIDKDYELSLQTPVYMDVMTYLDNRDLREEVYIAYISRAS
                     DLGITATNYNNKPIMDEILLLRSEMANILGFEHYAQLSITSKMVNTVDEVVQFLSDLV
                     EYSKSQAQLELEELKIFSGIDLKPWDLEFYSEKLKEQKFGFKKSDLTPYFPENSVLKG
                     LFLTIENLYQIKIKQIQQNSYHTDVKVLDVNNESGVIGRIYLDLYARENKRSGAWMTD
                     YQPLINNQKPVAFVVCNFNSPTKDKPALFEFDEIVTLFHEFGHVLHHLLTKVKYPCAS
                     GISGVPWDGVELPSQYMEFYVFEKQVISLISSHYKTRKPLPDELYNKLIASKNFNSAL
                     SMLRQCEFALWDLKTHMSTRDSYTILKQVQRKTSLMPMINENRFLNTFEHIFSGGYAA
                     GYFSYKWAEVLAADAYYYVQKKGGIGSDASRDFLYNILEIGGSLDFMQQYIKFRGENP
                     SVNALLKANGIIHSTKERHD"
     misc_feature    complement(549318..551132)
                     /gene="prlC"
                     /locus_tag="COSY_0523"
                     /note="Zn-dependent oligopeptidases [Amino acid transport
                     and metabolism]; Region: Dcp; COG0339"
                     /db_xref="CDD:223416"
     misc_feature    complement(549324..551132)
                     /gene="prlC"
                     /locus_tag="COSY_0523"
                     /note="Peptidase family M3 dipeptidyl carboxypeptidase
                     (DCP); Region: M3A_DCP; cd06456"
                     /db_xref="CDD:188995"
     misc_feature    complement(order(549516..549518,549525..549527,
                     549537..549545,549555..549560,549576..549581,
                     549690..549692,549837..549839,549846..549848,
                     549924..549926,549933..549938,550059..550067))
                     /gene="prlC"
                     /locus_tag="COSY_0523"
                     /note="active site"
                     /db_xref="CDD:188995"
     misc_feature    complement(order(549846..549848,549924..549926,
                     549936..549938))
                     /gene="prlC"
                     /locus_tag="COSY_0523"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188995"
     gene            complement(551241..551329)
                     /locus_tag="COSY_t19"
                     /db_xref="GeneID:5329763"
     tRNA            complement(551241..551329)
                     /locus_tag="COSY_t19"
                     /product="tRNA-Ser"
                     /db_xref="GeneID:5329763"
     gene            complement(551517..553154)
                     /gene="metG"
                     /locus_tag="COSY_0525"
                     /db_xref="GeneID:5171801"
     CDS             complement(551517..553154)
                     /gene="metG"
                     /locus_tag="COSY_0525"
                     /EC_number="6.1.1.10"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA synthetase"
                     /protein_id="YP_001219367.1"
                     /db_xref="GI:148244673"
                     /db_xref="GeneID:5171801"
                     /translation="MTSRKILVTSALPYANGEIHLGHLLEYIQTDIWVRFQKMMGNEC
                     HYVCADDAHGTAIMLKADELDITPEVLIKNMSNKHQIDFQSFSIDFSQYHSTHSQENK
                     DISTNIYNKLNVAGFIKTRVISQAFDPLKQMFLADRFIKGDCPKCGSNEQYGDNCEVC
                     GATYSSIELKNAKSVISGVTPITKDSEHYFFDLPQFEVQLKEWTKAGHLQDAISNKLS
                     EWFKEGLQQWDISRDAPYFGFQIPAVEGKYFYVWLDAPIGYMASFKKLCDEQNIDFNE
                     YFNKDSNTELYHFIGKDIIYFHALFWPAMLIGSNYRTPSAIFAHGFLTINGQKMSKSR
                     GTFIQARTYLNYLNPEYLRYYYAYKLSSKIDDIDLNLIDFKQRINSDLVGKVVNIASR
                     SAGFIVKKFNKTLSSYTIESKFYQEFFDCGDIIAKHYEARNYNQAMRVIIKLANKANQ
                     YIDKHKPWQLIKKPNQQTQVHDVTSLAINLFRVLMTYLKPVLPIMAKQVEKFLNIDEL
                     HWQDLKYPLIKHQINTFKPLMLRIEDDQIERIIEASK"
     misc_feature    complement(551568..553151)
                     /gene="metG"
                     /locus_tag="COSY_0525"
                     /note="methionyl-tRNA synthetase; Reviewed; Region:
                     PRK12268"
                     /db_xref="CDD:237029"
     misc_feature    complement(552072..553142)
                     /gene="metG"
                     /locus_tag="COSY_0525"
                     /note="catalytic core domain of methioninyl-tRNA
                     synthetases; Region: MetRS_core; cd00814"
                     /db_xref="CDD:173907"
     misc_feature    complement(order(552261..552263,552273..552275,
                     552378..552380,552387..552392,552399..552401,
                     553002..553004,553113..553115,553119..553124))
                     /gene="metG"
                     /locus_tag="COSY_0525"
                     /note="active site"
                     /db_xref="CDD:173907"
     misc_feature    complement(553086..553097)
                     /gene="metG"
                     /locus_tag="COSY_0525"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173907"
     misc_feature    complement(552156..552170)
                     /gene="metG"
                     /locus_tag="COSY_0525"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:173907"
     misc_feature    complement(551646..552038)
                     /gene="metG"
                     /locus_tag="COSY_0525"
                     /note="Anticodon-binding domain of methionyl tRNA
                     synthetases; Region: Anticodon_Ia_Met; cd07957"
                     /db_xref="CDD:153411"
     misc_feature    complement(order(551781..551783,551799..551801,
                     551967..551972,551979..551984,551991..551996,
                     552003..552008,552018..552020))
                     /gene="metG"
                     /locus_tag="COSY_0525"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:153411"
     misc_feature    complement(order(551781..551783,551796..551801,
                     551805..551810,551967..551972,551979..551984,
                     551991..551996,552003..552008,552015..552020))
                     /gene="metG"
                     /locus_tag="COSY_0525"
                     /note="tRNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:153411"
     gene            553236..554309
                     /gene="mrp"
                     /locus_tag="COSY_0526"
                     /db_xref="GeneID:5172108"
     CDS             553236..554309
                     /gene="mrp"
                     /locus_tag="COSY_0526"
                     /note="ATP-binding protein involved in chromosome
                     partitioning"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp-ATPase"
                     /protein_id="YP_001219368.1"
                     /db_xref="GI:148244674"
                     /db_xref="GeneID:5172108"
                     /translation="MVNLTNKKIKIILSKIVDIYTEQNIISSNNINIDGDKVQINIEL
                     NYPANSYHTTLSNTITDALTKNGINNHSVDIKTKIVKYTTQKGVDTLPEVKNIIAIAS
                     GKGGVGKSTTAVNLALALQAEGAKVAILDADIYGPSQPRMLGVSKIKPESSTEGKLLP
                     ILGHGIQSMSIGYLVKEDNPMIWRGPMITQALEQMLRDTLWRGIDYMIIDLPPGTGDT
                     QLTLSQKIPVSGSIIVTTPQDIALIDAKKGLKMFEKVNIPILGIVENMSLHICSKCGY
                     EEAIFGTGGGKAMAINEGIEFLGSLPLKMDIQTDVDEGTPTVTKDPEGKIAKIYKEIA
                     KKVSAKLTQQSRVTNAFPSITIE"
     misc_feature    553524..554198
                     /gene="mrp"
                     /locus_tag="COSY_0526"
                     /note="MinD superfamily P-loop ATPase containing an
                     inserted ferredoxin domain [Energy production and
                     conversion]; Region: COG1149"
                     /db_xref="CDD:224071"
     misc_feature    553524..554150
                     /gene="mrp"
                     /locus_tag="COSY_0526"
                     /note="MRP (Multiple Resistance and pH adaptation) is a
                     homologue of the Fer4_NifH superfamily. Like the other
                     members of the superfamily, MRP contains a ATP-binding
                     domain at the N-termini. It is found in bacteria as a
                     membrane-spanning protein and functions...; Region:
                     MRP-like; cd02037"
                     /db_xref="CDD:238994"
     misc_feature    553542..553565
                     /gene="mrp"
                     /locus_tag="COSY_0526"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:238994"
     gene            complement(554560..554898)
                     /gene="fdx"
                     /locus_tag="COSY_0527"
                     /db_xref="GeneID:5172043"
     CDS             complement(554560..554898)
                     /gene="fdx"
                     /locus_tag="COSY_0527"
                     /note="ferredoxin, 2Fe-2S"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="YP_001219369.1"
                     /db_xref="GI:148244675"
                     /db_xref="GeneID:5172043"
                     /translation="MPQIIVLPHHELCPEGIIINIQSGVSICDALLADDVEIEHACEM
                     SSACTTCHVYLREGFDSVEESDEIEDDLLDKAWGLEPDSRLSCQTIMGNTDLVIEIPK
                     YTINQVSENH"
     misc_feature    complement(554587..554898)
                     /gene="fdx"
                     /locus_tag="COSY_0527"
                     /note="Ferredoxin [Energy production and conversion];
                     Region: Fdx; COG0633"
                     /db_xref="CDD:223706"
     misc_feature    complement(554602..554859)
                     /gene="fdx"
                     /locus_tag="COSY_0527"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(554638..554643,554746..554757,
                     554761..554763,554773..554775,554782..554787))
                     /gene="fdx"
                     /locus_tag="COSY_0527"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(554638..554640,554746..554748,
                     554755..554757,554773..554775))
                     /gene="fdx"
                     /locus_tag="COSY_0527"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     gene            complement(554921..556765)
                     /gene="hscA"
                     /locus_tag="COSY_0528"
                     /db_xref="GeneID:5172015"
     CDS             complement(554921..556765)
                     /gene="hscA"
                     /locus_tag="COSY_0528"
                     /note="involved in the maturation of iron-sulfur
                     cluster-containing proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone protein HscA"
                     /protein_id="YP_001219370.1"
                     /db_xref="GI:148244676"
                     /db_xref="GeneID:5172015"
                     /translation="MTLLQISEPSQVSKPHQHKLVIGIDLGTTNSLVASVINGQSKVI
                     MDENNEAVLPSIIHCGKHNKLTVGCDAYPYAKTDPTNTIISIKRFMGMSYEEVSTFKN
                     CPYQLIKDGNNVLFHTSMGNLSAVEISASILSSLKQRAENSLGGVLSGAVITTPAYFN
                     DAQRQATKDAATLAGLKTLRLLNEPTAAAVAYGLESGEEGVHAIYDLGGGTFDISILN
                     FSKGVFKVLAIGGDATLGGDDFDELIINDCIEQLSINELTPAQMQEIKQFSRIAKETL
                     SNYEFSEFDCIKRPYCITKKKFETLAKVLIKRTLLLTKQAIRDAQVDVKNIKNIIMVG
                     GSTRIPLVCSMVSDLFNKPVLCSINPDEVVAKGAAIQANILAGIKSQNDILLLDVLPL
                     SLGLETMGGLVEKIIHRNTTIPIIRAQEFTTFKDGQTAMSIHVLQGERELVRDCRSLA
                     KFDLYGIPAMVAGNARIRIEFQVDVDGLLSVSAVEQISGVKTNISIKPSYGLTDVQKE
                     KMLKDSFLFAKTDIQTRKLHETQVEANRTIEAIDSAIKKDKNMLDDKMLNNILNARNT
                     LFDIVHSDDEKAISIAIENLENSCLKFVEMRMNSSVMKAIQGRNIDEF"
     misc_feature    complement(554924..556765)
                     /gene="hscA"
                     /locus_tag="COSY_0528"
                     /note="chaperone protein HscA; Provisional; Region: hscA;
                     PRK05183"
                     /db_xref="CDD:235360"
     misc_feature    complement(555647..556708)
                     /gene="hscA"
                     /locus_tag="COSY_0528"
                     /note="Nucleotide-binding domain of HscA and similar
                     proteins; Region: HscA_like_NBD; cd10236"
                     /db_xref="CDD:212678"
     misc_feature    complement(order(555683..555685,555749..555754,
                     555758..555766,555944..555949,555956..555958,
                     556052..556057,556127..556129,556133..556150,
                     556214..556216,556298..556300,556505..556507,
                     556676..556687,556691..556693))
                     /gene="hscA"
                     /locus_tag="COSY_0528"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212678"
     misc_feature    complement(order(555908..555913,555917..555919,
                     555953..555955,555965..555967,555974..555979,
                     555986..555988,556337..556342,556547..556552,
                     556559..556561,556571..556573,556622..556624))
                     /gene="hscA"
                     /locus_tag="COSY_0528"
                     /note="putative NEF/HSP70 interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:212678"
     misc_feature    complement(order(556085..556096,556217..556219,
                     556223..556228,556271..556276,556280..556285))
                     /gene="hscA"
                     /locus_tag="COSY_0528"
                     /note="SBD interface [polypeptide binding]; other site"
                     /db_xref="CDD:212678"
     gene            complement(556781..557296)
                     /gene="hscB"
                     /locus_tag="COSY_0529"
                     /db_xref="GeneID:5172660"
     CDS             complement(556781..557296)
                     /gene="hscB"
                     /locus_tag="COSY_0529"
                     /note="Hsc20"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HscB"
                     /protein_id="YP_001219371.1"
                     /db_xref="GI:148244677"
                     /db_xref="GeneID:5172660"
                     /translation="MENYFELFSIKPDFNISIINLNAEYQKQIVKFHPDRFITSSAKE
                     RVLALQNTSLINTAFDTLKSPLNRANYLLELNGIDAFDEKYTQMDVKFLMNQIELREN
                     LELIRISKDEIRLYDFIEKNDLNIKHNVDNIRLLFTNTKTFNEIKNLVRELKFYEHLN
                     THAKQLMNEWL"
     misc_feature    complement(556799..557290)
                     /gene="hscB"
                     /locus_tag="COSY_0529"
                     /note="co-chaperone HscB; Provisional; Region: hscB;
                     PRK05014"
                     /db_xref="CDD:179914"
     misc_feature    complement(557081..557290)
                     /gene="hscB"
                     /locus_tag="COSY_0529"
                     /note="DnaJ domain; Region: DnaJ; pfam00226"
                     /db_xref="CDD:215804"
     misc_feature    complement(order(557126..557131,557138..557143,
                     557150..557152,557192..557200))
                     /gene="hscB"
                     /locus_tag="COSY_0529"
                     /note="HSP70 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99751"
     misc_feature    complement(556802..557035)
                     /gene="hscB"
                     /locus_tag="COSY_0529"
                     /note="HSCB C-terminal oligomerisation domain; Region:
                     HSCB_C; pfam07743"
                     /db_xref="CDD:219548"
     gene            complement(557309..557632)
                     /gene="iscA"
                     /locus_tag="COSY_0530"
                     /db_xref="GeneID:5172659"
     CDS             complement(557309..557632)
                     /gene="iscA"
                     /locus_tag="COSY_0530"
                     /note="nitrogen fixation protein HesB"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein"
                     /protein_id="YP_001219372.1"
                     /db_xref="GI:148244678"
                     /db_xref="GeneID:5172659"
                     /translation="MAVTLTEHAVERIVEFLTNRGSGIGIRLRVQTTGCSGLGYNMEF
                     VDYTFDDDTVFEDNGVKIIVDAKSLIYLDGTQVDYVKKGLNEGFEFNNPNAKAECGCG
                     ESFTV"
     misc_feature    complement(557312..557626)
                     /gene="iscA"
                     /locus_tag="COSY_0530"
                     /note="Iron-sulphur cluster biosynthesis; Region:
                     Fe-S_biosyn; cl00400"
                     /db_xref="CDD:241842"
     gene            complement(557639..558016)
                     /gene="iscU"
                     /locus_tag="COSY_0531"
                     /db_xref="GeneID:5172738"
     CDS             complement(557639..558016)
                     /gene="iscU"
                     /locus_tag="COSY_0531"
                     /note="nitrogen fixation protein NifU and related
                     proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="scaffold protein"
                     /protein_id="YP_001219373.1"
                     /db_xref="GI:148244679"
                     /db_xref="GeneID:5172738"
                     /translation="MAYGKKVMDHYENPRNVGVLDKNAKNVGTGMVGAPACGDVMRLQ
                     IKIDDNGVIEDAKFKTYGCGSAIASSSLLTQWVKGKTLDEATKIKNSDIAEELSLPPV
                     KIHCSVLAEDAIKAAINDIKSKI"
     misc_feature    complement(557645..558016)
                     /gene="iscU"
                     /locus_tag="COSY_0531"
                     /note="NifU homolog involved in Fe-S cluster formation
                     [Energy production and conversion]; Region: IscU; COG0822"
                     /db_xref="CDD:223892"
     misc_feature    complement(557666..558010)
                     /gene="iscU"
                     /locus_tag="COSY_0531"
                     /note="Iron-sulfur cluster scaffold-like proteins; Region:
                     IscU_like; cd06664"
                     /db_xref="CDD:143480"
     misc_feature    complement(order(557699..557704,557708..557713,
                     557822..557824,557828..557830,557903..557908,
                     557990..557995,558002..558010))
                     /gene="iscU"
                     /locus_tag="COSY_0531"
                     /note="trimerization site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143480"
     misc_feature    complement(order(557699..557701,557828..557830,
                     557906..557908))
                     /gene="iscU"
                     /locus_tag="COSY_0531"
                     /note="active site"
                     /db_xref="CDD:143480"
     gene            complement(558084..559298)
                     /gene="iscS"
                     /locus_tag="COSY_0532"
                     /db_xref="GeneID:5172586"
     CDS             complement(558084..559298)
                     /gene="iscS"
                     /locus_tag="COSY_0532"
                     /EC_number="2.8.1.7"
                     /note="catalyzes the removal of elemental sulfur from
                     cysteine to produce alanine; involved in NAD biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="YP_001219374.1"
                     /db_xref="GI:148244680"
                     /db_xref="GeneID:5172586"
                     /translation="MSIPTYMDYSATTPVDERVAQKMIQFLTKDGNFGNSASNSHYYG
                     WQADEAVKKARQQVANLIDADPKEIVWTSGATESNNLAIKGVAHFYHKKGKHIITLKT
                     EHKSVLDTCRQLEREGFEVTYLDPMSNGLLDLNILRDAMREDTILVSIMHVNNEIGVI
                     QDIESIGNLCHQNNIFFHVDAAQSAGKVAISLSELSVDLMSFSAHKIYGPKGMGALYV
                     RRKPRVRIEAQMHGGGHERGMRSGTLATHQIVGMGEAFAIAQAEMREENTKIRQLRDR
                     LLVGFIDMEEVVVNGDMESRIPGNLNISFNYVEGESLMMAINDIAVSSGSACTSLSLE
                     PSYVLRALGLNDELAHSSIRFTIGRYTTEAQIDKAIDLVRAKVDKLRDLSPLWDMFKD
                     GVDISKVEWSAH"
     misc_feature    complement(558087..559298)
                     /gene="iscS"
                     /locus_tag="COSY_0532"
                     /note="cysteine desulfurase; Provisional; Region:
                     PRK14012"
                     /db_xref="CDD:184450"
     misc_feature    complement(558141..559283)
                     /gene="iscS"
                     /locus_tag="COSY_0532"
                     /note="cysteine desulfurase NifS; Region: FeS_nifS;
                     TIGR03402"
                     /db_xref="CDD:132443"
     misc_feature    complement(order(558681..558683,558690..558692,
                     558750..558752,558759..558761,558843..558845,
                     559062..559064,559071..559076))
                     /gene="iscS"
                     /locus_tag="COSY_0532"
                     /note="pyridoxal 5'-phosphate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:99742"
     misc_feature    complement(558681..558683)
                     /gene="iscS"
                     /locus_tag="COSY_0532"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99742"
     gene            complement(559301..559720)
                     /gene="iscR"
                     /locus_tag="COSY_0533"
                     /db_xref="GeneID:5172716"
     CDS             complement(559301..559720)
                     /gene="iscR"
                     /locus_tag="COSY_0533"
                     /note="Rrf2 family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster-containing transcription factor"
                     /protein_id="YP_001219375.1"
                     /db_xref="GI:148244681"
                     /db_xref="GeneID:5172716"
                     /translation="MQLTTKGRYAVTAILDLASNDTGKPITLDIISQRQNISLSYLEQ
                     LFAKLRRAELVKSVRGPGGGYLLDAKACDINLTQIIEAVDENIDLRRCKGIKVCNNGR
                     QCISHQLWCEVSEQIRTFLNGKTLQMVIDDHNSNKGV"
     misc_feature    complement(559319..559720)
                     /gene="iscR"
                     /locus_tag="COSY_0533"
                     /note="Transcriptional regulator; Region: Rrf2; cl17282"
                     /db_xref="CDD:247836"
     misc_feature    complement(559328..559720)
                     /gene="iscR"
                     /locus_tag="COSY_0533"
                     /note="Rrf2 family protein; Region: rrf2_super; TIGR00738"
                     /db_xref="CDD:129821"
     gene            complement(559803..560501)
                     /gene="cysE"
                     /locus_tag="COSY_0534"
                     /db_xref="GeneID:5172709"
     CDS             complement(559803..560501)
                     /gene="cysE"
                     /locus_tag="COSY_0534"
                     /EC_number="2.3.1.30"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="YP_001219376.1"
                     /db_xref="GI:148244682"
                     /db_xref="GeneID:5172709"
                     /translation="MKFIEDIQSIFDRDPAARNIFEIITCYSGVQAMLFYRLSHRLWK
                     FKFKWLARFVSSLARWFTGIEIHPGAVIGRRFFIDHGMGVVIGETAEIGDDCTLYHGV
                     TLGGTTWQKGKRHPILGNNVVIGAGAKILGPIVLADNVRVGSNSVVVKSIDKSQIVVG
                     VPGRILKNNKIQSNHFDSYAVGNNVDDPTVEAINFILLHLHDVDFQLHKISKKLNIKD
                     QQGASMNDLEIESK"
     misc_feature    complement(560010..560489)
                     /gene="cysE"
                     /locus_tag="COSY_0534"
                     /note="serine O-acetyltransferase; Region: cysE;
                     TIGR01172"
                     /db_xref="CDD:200082"
     misc_feature    complement(560016..560318)
                     /gene="cysE"
                     /locus_tag="COSY_0534"
                     /note="Serine acetyltransferase (SAT): SAT catalyzes the
                     CoA-dependent acetylation of the side chain hydroxyl group
                     of L-serine to form O-acetylserine, as the first step of a
                     two-step biosynthetic pathway in bacteria and plants
                     leading to the formation of...; Region: LbH_SAT; cd03354"
                     /db_xref="CDD:100045"
     misc_feature    complement(order(560055..560057,560061..560063,
                     560070..560072,560160..560162,560262..560264,
                     560307..560309,560313..560315))
                     /gene="cysE"
                     /locus_tag="COSY_0534"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100045"
     misc_feature    complement(order(560016..560018,560031..560033,
                     560055..560057,560061..560063,560070..560075,
                     560079..560081,560124..560126,560157..560162,
                     560181..560186,560202..560207,560262..560267))
                     /gene="cysE"
                     /locus_tag="COSY_0534"
                     /note="active site"
                     /db_xref="CDD:100045"
     misc_feature    complement(order(560157..560162,560184..560186,
                     560262..560267))
                     /gene="cysE"
                     /locus_tag="COSY_0534"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100045"
     misc_feature    complement(order(560016..560018,560031..560033,
                     560055..560057,560061..560063,560070..560075,
                     560079..560081,560124..560126,560181..560186,
                     560202..560207))
                     /gene="cysE"
                     /locus_tag="COSY_0534"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:100045"
     gene            complement(560570..561430)
                     /locus_tag="COSY_0535"
                     /db_xref="GeneID:5172162"
     CDS             complement(560570..561430)
                     /locus_tag="COSY_0535"
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A biosynthesis lauroyl acyltransferase"
                     /protein_id="YP_001219377.1"
                     /db_xref="GI:148244683"
                     /db_xref="GeneID:5172162"
                     /translation="MKPRKVRMIRFILWIFSIIPLKLNHFIGTVIGQYLYLTKSNSRA
                     IVSKNIQLCFPGLNSKQQQILIRKSLIESGKGLSESGFIWFKNFDDNVKYVTKTLGIQ
                     HLRSNKAVILLVPHFGCWELVARMISLTKPVTFMYKILKNKQQNRLLLSKREQGDLLM
                     VPANKKGVIKLQRAINKKQLIAILPDQDPGEMGSILAPFFSQDTRTMTLLVRLTRKNN
                     AQVIMAWTKRLPNAKGYELNLKPVQILSDTNILGDDVSLMNKVIEDLVTTQPEQYLWN
                     YKRFKSVIKY"
     misc_feature    complement(560585..561400)
                     /locus_tag="COSY_0535"
                     /note="Bacterial lipid A biosynthesis acyltransferase;
                     Region: Lip_A_acyltrans; pfam03279"
                     /db_xref="CDD:112109"
     misc_feature    complement(560588..561127)
                     /locus_tag="COSY_0535"
                     /note="Lysophospholipid Acyltransferases (LPLATs) of
                     Glycerophospholipid Biosynthesis: LABLAT-like; Region:
                     LPLAT_LABLAT-like; cd07984"
                     /db_xref="CDD:153246"
     misc_feature    complement(order(560864..560872,561011..561022,
                     561068..561070,561074..561076,561083..561085))
                     /locus_tag="COSY_0535"
                     /note="putative acyl-acceptor binding pocket; other site"
                     /db_xref="CDD:153246"
     gene            complement(561411..562151)
                     /locus_tag="COSY_0536"
                     /db_xref="GeneID:5172106"
     CDS             complement(561411..562151)
                     /locus_tag="COSY_0536"
                     /note="cell cycle control ATPase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219378.1"
                     /db_xref="GI:148244684"
                     /db_xref="GeneID:5172106"
                     /translation="MVNPRIVLPKLLVKLVGRAINDFKMIKKDDKVLLAVSGGKDSLS
                     LFHIFRHFLVSAPIYFEFGVVTIDPKIDGFEPQALEYFFRKFDTPYFFETFSIMKQAE
                     KSMKGNSYCSFCARIKRGLMYQVARREGYNVLALGHHLDDLAESLMMSMCHNGKIQTM
                     KAHYINDAKDLRVIRPLTYVRERQLADFAKITHLPVIKDSCPACYQMPTERMHFKKWL
                     LTEEKRTPNLYKNLLSAMKPMLDETKKG"
     misc_feature    complement(561540..562061)
                     /locus_tag="COSY_0536"
                     /note="This is a subfamily of Adenine nucleotide alpha
                     hydrolases superfamily.Adeninosine nucleotide alpha
                     hydrolases superfamily  includes N type ATP PPases and ATP
                     sulphurylases. It forms a apha/beta/apha fold which  binds
                     to Adenosine group.  This subfamily; Region:
                     Alpha_ANH_like_II; cd01993"
                     /db_xref="CDD:238951"
     misc_feature    complement(order(561948..561950,561954..561956,
                     562026..562037,562041..562049))
                     /locus_tag="COSY_0536"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238951"
     gene            complement(562691..564061)
                     /locus_tag="COSY_0537"
                     /db_xref="GeneID:5172103"
     CDS             complement(562691..564061)
                     /locus_tag="COSY_0537"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219379.1"
                     /db_xref="GI:148244685"
                     /db_xref="GeneID:5172103"
                     /translation="MKKHFIFIFIFIFCFNSKAMTQNKFIERLEDIHPFFTKLDLSLQ
                     IKKIDQQETTANQNWLVGVKTNFNNVDIDNNLNTISVDFLATKKIVSSGADITFKHSW
                     RQQNKNTTTNVDTNNSKFSIDYVHPLLKNASGINDKLNTGLSSINMQISKLNIAEQKE
                     AFILVQLKKFIDLAYIQERLIIDNQRLDLAAQELTLVKQKFKMAVIDKVDVLLQEDAY
                     HSAKHRQLQTQQYLNILRYELSIILDINLYSVKAEFDLYKPYIINKDDLKQYLLANSR
                     VLKIADLNQDLLELQLKSDKSNSKAKFDLKLGITNESKNSYYTNSIFNPSSSWNIGLD
                     FSYPIGNIQAKSNITKTQIMLAKAKEKKQEQLLNIYAKANVLKQKIKYLVEILELSKA
                     QIKTAKARTIEERRRYNNANSQISFVIAAQNNEQSVNLNYIQVFKNYQELVLNFKEII
                     DQLSPL"
     misc_feature    complement(563333..>563617)
                     /locus_tag="COSY_0537"
                     /note="Outer membrane efflux protein; Region: OEP;
                     pfam02321"
                     /db_xref="CDD:202204"
     misc_feature    complement(562712..563269)
                     /locus_tag="COSY_0537"
                     /note="Outer membrane efflux protein; Region: OEP;
                     pfam02321"
                     /db_xref="CDD:202204"
     gene            complement(564058..564582)
                     /gene="aroK"
                     /locus_tag="COSY_0538"
                     /db_xref="GeneID:5172095"
     CDS             complement(564058..564582)
                     /gene="aroK"
                     /locus_tag="COSY_0538"
                     /EC_number="2.7.1.71"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase I"
                     /protein_id="YP_001219380.1"
                     /db_xref="GI:148244686"
                     /db_xref="GeneID:5172095"
                     /translation="MSSNSSRNIILVGPMGSGKTSVGRRLACILNRDFFDSDFEIVAR
                     TGVSINHIFDVEGEKGFRKREMQILADLCEIKHIVIATGGGIVINPQNRKILKQGNFV
                     IYLSSTVEQLLKYTMNSKSRPLLEQSYDREKTFNNLLLKRGPLYQTVADVVIDTTSKK
                     LYAIISEIIKVIPI"
     misc_feature    complement(564064..564564)
                     /gene="aroK"
                     /locus_tag="COSY_0538"
                     /note="shikimate kinase; Reviewed; Region: aroK; PRK00131"
                     /db_xref="CDD:234654"
     misc_feature    complement(564115..564561)
                     /gene="aroK"
                     /locus_tag="COSY_0538"
                     /note="Shikimate kinase (SK) is the fifth enzyme in the
                     shikimate pathway, a seven-step biosynthetic pathway which
                     converts erythrose-4-phosphate to chorismic acid, found in
                     bacteria, fungi and plants. Chorismic acid is a important
                     intermediate in the synthesis...; Region: SK; cd00464"
                     /db_xref="CDD:238260"
     misc_feature    complement(order(564217..564219,564238..564240,
                     564520..564537))
                     /gene="aroK"
                     /locus_tag="COSY_0538"
                     /note="ADP binding site [chemical binding]; other site"
                     /db_xref="CDD:238260"
     misc_feature    complement(order(564469..564471,564475..564477,
                     564523..564525))
                     /gene="aroK"
                     /locus_tag="COSY_0538"
                     /note="magnesium binding site [ion binding]; other site"
                     /db_xref="CDD:238260"
     misc_feature    complement(order(564157..564159,564328..564336,
                     564388..564390,564397..564399,564469..564471))
                     /gene="aroK"
                     /locus_tag="COSY_0538"
                     /note="putative shikimate binding site; other site"
                     /db_xref="CDD:238260"
     gene            complement(564784..565713)
                     /gene="ilvE"
                     /locus_tag="COSY_0539"
                     /db_xref="GeneID:5172226"
     CDS             complement(564784..565713)
                     /gene="ilvE"
                     /locus_tag="COSY_0539"
                     /EC_number="2.6.1.42"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="YP_001219381.1"
                     /db_xref="GI:148244687"
                     /db_xref="GeneID:5172226"
                     /translation="MHTFDDRDGLIWFDGYWIDWREAKVHVLTHTLHYGMGVFEGIRA
                     YETKKGAAIFRLEEHVNRLFNSAKIMNMDIGFSKDKLNQVSKDAVAKNNLDSAYIRPM
                     CFYGSEGMGLRADGLKVHTIIAAWEWGSYLGEDNMKNGIRVRTSSYTRHHVNITMTKA
                     KANGNYINSMLALQEALIDGYDEALLLDVDGFVAEGSGENIFIVQDSVIYTPSLTSAL
                     AGITRDTVFKLATDLGYKVIEKHITRDEVYISDEAFFTGTAAEITPIRELDNRIIGLG
                     TRGPVTEQLQTLYFNCVYGRNEQYQHWIVKGFC"
     misc_feature    complement(564823..565692)
                     /gene="ilvE"
                     /locus_tag="COSY_0539"
                     /note="Branched-chain amino acid
                     aminotransferase/4-amino-4-deoxychorismate lyase [Amino
                     acid transport and metabolism / Coenzyme metabolism];
                     Region: IlvE; COG0115"
                     /db_xref="CDD:223193"
     misc_feature    complement(564829..565644)
                     /gene="ilvE"
                     /locus_tag="COSY_0539"
                     /note="BCAT_beta_family: Branched-chain aminotransferase
                     catalyses the transamination of the branched-chain amino
                     acids  leusine, isoleucine and valine to their respective
                     alpha-keto acids, alpha-ketoisocaproate,
                     alpha-keto-beta-methylvalerate and...; Region:
                     BCAT_beta_family; cd01557"
                     /db_xref="CDD:238798"
     misc_feature    complement(order(565150..565152,565192..565194,
                     565204..565206,565210..565212,565225..565227,
                     565348..565350,565372..565374,565384..565392,
                     565408..565410,565414..565416,565507..565509,
                     565597..565599,565603..565605,565609..565623,
                     565630..565644))
                     /gene="ilvE"
                     /locus_tag="COSY_0539"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238798"
     misc_feature    complement(order(564940..564942,565048..565053,
                     565129..565131,565216..565218,565231..565233,
                     565378..565380,565528..565530,565597..565599,
                     565612..565614))
                     /gene="ilvE"
                     /locus_tag="COSY_0539"
                     /note="substrate-cofactor binding pocket; other site"
                     /db_xref="CDD:238798"
     misc_feature    complement(565231..565233)
                     /gene="ilvE"
                     /locus_tag="COSY_0539"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238798"
     gene            complement(565716..566939)
                     /locus_tag="COSY_0540"
                     /db_xref="GeneID:5172712"
     CDS             complement(565716..566939)
                     /locus_tag="COSY_0540"
                     /EC_number="2.7.2.4"
                     /note="catalyzes the formation of 4-phospho-L-aspartate
                     from L-aspartate and ATP, in Bacillus, lysine sensitive;
                     regulated by response to starvation."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="YP_001219382.1"
                     /db_xref="GI:148244688"
                     /db_xref="GeneID:5172712"
                     /translation="MALIVQKYGGTSVASVERIQAVAQKIKAFKEKGHQLVVSVSAMS
                     GETSRMTALAQTIQDIPSLREMDVLLTTGEQVTIALLTMALQQLGCDAVSYTGPQVCI
                     MTDSEHGKARIKSIDNHRIFHSLDQGKVVVVAGFQGVDENGHITTLGRGGSDTTAVAL
                     VTALKADECQIYTDVDGVFTTDPRIEINARRINVVSYEEMLEMASLGSKVLQIRSVEF
                     ASKYKVPLRVLSSLIDNPLGTLITREENIVEQVVISGIAHNKDEAKLSLIGVLDEPGI
                     AFKILNPISSANIEVDMIVQSVSAREGLTNFAFTVHRNNFKTASKILNNVCKEIGAIA
                     VQSDDKVVKVSLVGIGIRSHAGIATQMFEVLHNEGINIQMISTSEIKISVVIDEKYLE
                     LAVRSLHAVFELDKE"
     misc_feature    complement(565725..566939)
                     /locus_tag="COSY_0540"
                     /note="aspartate kinase; Reviewed; Region: PRK06635"
                     /db_xref="CDD:235843"
     misc_feature    complement(566214..566933)
                     /locus_tag="COSY_0540"
                     /note="AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily
                     (AAK), AKii; this CD includes the N-terminal catalytic
                     aspartokinase (AK) domain of the lysine-sensitive
                     aspartokinase isoenzyme AKII of Bacillus subtilis 168, and
                     the lysine plus threonine-sensitive...; Region:
                     AAK_AKii-LysC-BS; cd04261"
                     /db_xref="CDD:239794"
     misc_feature    complement(order(566403..566408,566415..566420,
                     566907..566915,566919..566921))
                     /locus_tag="COSY_0540"
                     /note="putative nucleotide binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239794"
     misc_feature    complement(order(566718..566720,566799..566801,
                     566919..566921))
                     /locus_tag="COSY_0540"
                     /note="putative catalytic residues [active]"
                     /db_xref="CDD:239794"
     misc_feature    complement(order(566394..566396,566478..566480,
                     566799..566801,566817..566819))
                     /locus_tag="COSY_0540"
                     /note="putative Mg ion binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239794"
     misc_feature    complement(order(566718..566720,566799..566801,
                     566814..566819))
                     /locus_tag="COSY_0540"
                     /note="putative aspartate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239794"
     misc_feature    complement(565929..566156)
                     /locus_tag="COSY_0540"
                     /note="ACT domains of the lysine-sensitive aspartokinase
                     isoenzyme AKII of Bacillus subtilis (BS) strain 168 and
                     related proteins; Region: ACT_AKii-LysC-BS-like_1;
                     cd04913"
                     /db_xref="CDD:153185"
     misc_feature    complement(order(566037..566039,566043..566045))
                     /locus_tag="COSY_0540"
                     /note="putative allosteric regulatory site; other site"
                     /db_xref="CDD:153185"
     misc_feature    complement(565728..565913)
                     /locus_tag="COSY_0540"
                     /note="ACT domains of the lysine-sensitive, aspartokinase
                     (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168
                     and related domains; Region: ACT_AKii-LysC-BS-like_2;
                     cd04936"
                     /db_xref="CDD:153208"
     gene            567344..568591
                     /locus_tag="COSY_0541"
                     /db_xref="GeneID:5171972"
     CDS             567344..568591
                     /locus_tag="COSY_0541"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M48, Ste24p"
                     /protein_id="YP_001219383.1"
                     /db_xref="GI:148244689"
                     /db_xref="GeneID:5171972"
                     /translation="MTSDLFTLIFLIAIFIYMTILLWLNIRQNKAIIQSFDKVPNEFR
                     KEITLKDHQKATEYTQAKLKLNHFEVIFSTTILLLWTLGGGLDYLDNIWQEQTDNILY
                     AGVGFIVSLIMLGSLIDLPFSVYRTFILEQKFGFNQTNIKTFITDLLKGALLVLVIGL
                     PLIYAILYLMDTMSEYWWFYVWLVLIVFSLLIFWLYPTYIAPIFNQFKPLDNIELKTK
                     INNLLERTGFRSDGIFVMNGSKRSSHANAYFTGIGKNKRIVFFDTLIKNMSDNEVQAI
                     LAHELGHCHHRHVIKHMISSFITSLLGLALLSYLINQNWFFHGLGISHPSNHSALILF
                     TLTIPVFSFLITPINNYLSRKYEFEADVFATKHTNANDLVSSLVKLYRDNAIILAPDY
                     MYSYFHDSHPSALIRINQIKTYK"
     misc_feature    567890..568570
                     /locus_tag="COSY_0541"
                     /note="Peptidase family M48; Region: Peptidase_M48;
                     pfam01435"
                     /db_xref="CDD:216503"
     gene            568654..568908
                     /locus_tag="COSY_0542"
                     /db_xref="GeneID:5171984"
     CDS             568654..568908
                     /locus_tag="COSY_0542"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219384.1"
                     /db_xref="GI:148244690"
                     /db_xref="GeneID:5171984"
                     /translation="MLVASSNALSNDKGKELHKESCITCHIVEHNNTFYTRNNSRLHN
                     HFDLRKQVSNCVNAFNINWLPDEEKSVVNHLNNEYYDFRK"
     gene            569023..569862
                     /locus_tag="COSY_0543"
                     /db_xref="GeneID:5172114"
     CDS             569023..569862
                     /locus_tag="COSY_0543"
                     /note="probable GTPase engC"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219385.1"
                     /db_xref="GI:148244691"
                     /db_xref="GeneID:5172114"
                     /translation="MVITRYKKRLLVKIKSGELYQCVTKNNIDLSVAGDRVIFQITQS
                     NQGIVTAILERHNQLYRTHKLIATNIDQLWLVVAMEPHYQFELIDRYLIMAENAKLPI
                     NIVVNKVELTNNIKKVKYDFSMYKNIGYSINYLSVKKQINIDKFKLKLNNKTHIFLGQ
                     SGVGKSSLINKLIPELNLRVNEISTKSKLGKHTTTNTTLYQIPSGGDLIDSPGIRKFQ
                     LDEFSNQEILNGFKEFNPFTNACKFRNCAHIFEPKCAIKLAVKLGDIHKKRYQSYITL
                     VSS"
     misc_feature    569023..569205
                     /locus_tag="COSY_0543"
                     /note="S1_like: Ribosomal protein S1-like RNA-binding
                     domain. Found in a wide variety of RNA-associated
                     proteins. Originally identified in S1 ribosomal protein.
                     This superfamily also contains the Cold Shock Domain
                     (CSD), which is a homolog of the S1 domain; Region:
                     S1_like; cl09927"
                     /db_xref="CDD:245202"
     misc_feature    order(569029..569031,569053..569055,569083..569085,
                     569089..569091)
                     /locus_tag="COSY_0543"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:238094"
     misc_feature    569053..569856
                     /locus_tag="COSY_0543"
                     /note="GTPase RsgA; Reviewed; Region: PRK00098"
                     /db_xref="CDD:234631"
     misc_feature    569227..569850
                     /locus_tag="COSY_0543"
                     /note="Ribosomal interacting GTPase YjeQ/EngC, a
                     circularly permuted subfamily of the Ras GTPases; Region:
                     YjeQ_EngC; cd01854"
                     /db_xref="CDD:206747"
     misc_feature    order(569275..569280,569287..569292,569296..569301,
                     569308..569313,569410..569412,569698..569700,
                     569710..569712,569716..569718,569827..569829,
                     569836..569838,569848..569850)
                     /locus_tag="COSY_0543"
                     /note="GTPase/Zn-binding domain interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:206747"
     misc_feature    order(569341..569346,569350..569355,569428..569433,
                     569506..569523)
                     /locus_tag="COSY_0543"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206747"
     misc_feature    569341..569352
                     /locus_tag="COSY_0543"
                     /note="G4 box; other site"
                     /db_xref="CDD:206747"
     misc_feature    569428..569436
                     /locus_tag="COSY_0543"
                     /note="G5 box; other site"
                     /db_xref="CDD:206747"
     misc_feature    569497..569520
                     /locus_tag="COSY_0543"
                     /note="G1 box; other site"
                     /db_xref="CDD:206747"
     misc_feature    569593..569616
                     /locus_tag="COSY_0543"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206747"
     misc_feature    569602..569604
                     /locus_tag="COSY_0543"
                     /note="G2 box; other site"
                     /db_xref="CDD:206747"
     misc_feature    569650..569661
                     /locus_tag="COSY_0543"
                     /note="G3 box; other site"
                     /db_xref="CDD:206747"
     misc_feature    569656..569664
                     /locus_tag="COSY_0543"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206747"
     gene            complement(570494..570871)
                     /locus_tag="COSY_0544"
                     /db_xref="GeneID:5172655"
     CDS             complement(570494..570871)
                     /locus_tag="COSY_0544"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219386.1"
                     /db_xref="GI:148244692"
                     /db_xref="GeneID:5172655"
                     /translation="MNFFWIFIALSGTMVIVMDAMSVHIFKYVLPIEDIMRIQTAITY
                     QMYHTLIIAILAIQSQRIIVKSINQSIWLFIAGIVMFSGSLYLYTLTKLYGLFFITPI
                     GGMLLVLGWLSIARFAFNFSKIK"
     misc_feature    complement(570503..570871)
                     /locus_tag="COSY_0544"
                     /note="Uncharacterized small membrane protein [Function
                     unknown]; Region: COG2363"
                     /db_xref="CDD:225238"
     gene            complement(571185..571260)
                     /locus_tag="COSY_t20"
                     /db_xref="GeneID:5329741"
     tRNA            complement(571185..571260)
                     /locus_tag="COSY_t20"
                     /product="tRNA-Lys"
                     /db_xref="GeneID:5329741"
     gene            complement(571354..571632)
                     /locus_tag="COSY_0546"
                     /db_xref="GeneID:5172654"
     CDS             complement(571354..571632)
                     /locus_tag="COSY_0546"
                     /note="bacterial nucleoid DNA-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor, beta subunit"
                     /protein_id="YP_001219387.1"
                     /db_xref="GI:148244693"
                     /db_xref="GeneID:5172654"
                     /translation="MKKPDLILNLSNSSNLSKTDAKIAVEVILEELTQGIVSGEGVEI
                     RGFGGFYKKYRKARQGINPKTSERTEVSEKFVPFFKPGKFLKEIINKI"
     misc_feature    complement(571372..571626)
                     /locus_tag="COSY_0546"
                     /note="Integration host factor (IHF) and HU are small
                     heterodimeric members of the DNABII protein family that
                     bind and bend DNA, functioning as architectural factors in
                     many cellular processes including transcription,
                     site-specific recombination, and...; Region: HU_IHF;
                     cd00591"
                     /db_xref="CDD:238332"
     misc_feature    complement(order(571384..571386,571393..571395,
                     571399..571401,571411..571413,571441..571452,
                     571459..571461,571465..571470,571474..571476,
                     571486..571488,571495..571500,571504..571506,
                     571510..571512,571555..571557,571621..571626))
                     /locus_tag="COSY_0546"
                     /note="IHF - DNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238332"
     misc_feature    complement(order(571390..571392,571396..571398,
                     571408..571413,571477..571479,571492..571497,
                     571504..571518,571528..571533,571540..571545,
                     571552..571554,571594..571596,571606..571608,
                     571615..571617,571624..571626))
                     /locus_tag="COSY_0546"
                     /note="IHF dimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238332"
     gene            complement(571665..573344)
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /db_xref="GeneID:5172632"
     CDS             complement(571665..573344)
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="in Escherichia coli this protein is involved in
                     binding to the leader sequence of mRNAs and is itself
                     bound to the 30S subunit; autoregulates expression via a
                     C-terminal domain; in most gram negative organisms this
                     protein is composed of 6 repeats of the S1 domain while in
                     gram positive there are 4 repeats; the S1 nucleic
                     acid-binding domain is found associated with other
                     proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="YP_001219388.1"
                     /db_xref="GI:148244694"
                     /db_xref="GeneID:5172632"
                     /translation="MSESFAELFENSAEQQNVKVGALLVGTVVSINREKAIVNVGLKS
                     EGFIPLDEFKNQQGELKVEEGDIVEVALKSIDDGLGNTLLSHADAKRIKLWHSLELAM
                     NSKEVVTGIVTGAVKGGLTVDIGVVKAFLPGSLVDVRPVKDFSYLTGQEIEAIVIKMD
                     EVRNNIVISRKAVLQEANSADREALLEELEEGKEIEGIVKNLADYGAFVDLGGVDGLL
                     HITDISWQRVNHPSEKLTIGDKIIVKVLNYDKEKMRVSLGLKQLTVSPWDSISDRLPI
                     GKKVQGTVSNLTDYGAFLSIEEGVEGLVHVSEMDWTNANARPSKIVKLGQEVEVVVLD
                     VQESKHRISLSMKQAQENPWESFEATHNKGDKIPVRVKSITDFGLFVGLLGGIDGLIH
                     LADISWEKQSSDQLVSSYSKGQELEVVILNIDAEKERISLGIKQLLEDEFMRYASANK
                     KGSIVRGMVMEVDSRGAVIRLNEDITGYLKAGEISEDRVEDATLILKTGEEIEVAILN
                     IDRRTRNILVSIKAKNSVEEKAAMEDYNKQSSDIVSGSTLGDLLKEAKDNK"
     misc_feature    complement(571668..573344)
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="30S ribosomal protein S1; Reviewed; Region: rpsA;
                     PRK06299"
                     /db_xref="CDD:235775"
     misc_feature    complement(573087..573284)
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1)
                     domain. RPS1 is a component of the small ribosomal subunit
                     thought to be involved in the recognition and binding of
                     mRNA&apos;s during translation initiation. The bacterial
                     RPS1 domain architecture...; Region:
                     S1_RPS1_repeat_ec1_hs1; cd05687"
                     /db_xref="CDD:240192"
     misc_feature    complement(order(573198..573200,573204..573206,
                     573234..573236,573258..573260))
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:240192"
     misc_feature    complement(572832..573032)
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1)
                     domain. RPS1 is a component of the small ribosomal subunit
                     thought to be involved in the recognition and binding of
                     mRNA&apos;s during translation initiation. The bacterial
                     RPS1 domain architecture...; Region:
                     S1_RPS1_repeat_ec2_hs2; cd04465"
                     /db_xref="CDD:239911"
     misc_feature    complement(order(572949..572951,572955..572957,
                     572982..572984,573006..573008))
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:239911"
     misc_feature    complement(572571..572750)
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1)
                     domain. RPS1 is a component of the small ribosomal subunit
                     thought to be involved in the recognition and binding of
                     mRNA&apos;s during translation initiation. The bacterial
                     RPS1 domain architecture consists...; Region:
                     S1_RPS1_repeat_ec3; cd05688"
                     /db_xref="CDD:240193"
     misc_feature    complement(order(572688..572690,572694..572696,
                     572721..572723,572745..572747))
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:240193"
     misc_feature    complement(572313..572522)
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="S1_like: Ribosomal protein S1-like RNA-binding
                     domain. Found in a wide variety of RNA-associated
                     proteins. Originally identified in S1 ribosomal protein.
                     This superfamily also contains the Cold Shock Domain
                     (CSD), which is a homolog of the S1 domain; Region:
                     S1_like; cl09927"
                     /db_xref="CDD:245202"
     misc_feature    complement(order(572430..572432,572436..572438,
                     572466..572468,572490..572492))
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:238094"
     misc_feature    complement(572046..572255)
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="S1_like: Ribosomal protein S1-like RNA-binding
                     domain. Found in a wide variety of RNA-associated
                     proteins. Originally identified in S1 ribosomal protein.
                     This superfamily also contains the Cold Shock Domain
                     (CSD), which is a homolog of the S1 domain; Region:
                     S1_like; cl09927"
                     /db_xref="CDD:245202"
     misc_feature    complement(order(572169..572171,572175..572177,
                     572205..572207,572229..572231))
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:238094"
     misc_feature    complement(571773..571991)
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1)
                     domain. RPS1 is a component of the small ribosomal subunit
                     thought to be involved in the recognition and binding of
                     mRNA&apos;s during translation initiation. The bacterial
                     RPS1 domain architecture consists...; Region:
                     S1_RPS1_repeat_ec6; cd05691"
                     /db_xref="CDD:240196"
     misc_feature    complement(order(571905..571907,571911..571913,
                     571941..571943,571965..571967))
                     /gene="rpsA"
                     /locus_tag="COSY_0547"
                     /note="RNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:240196"
     gene            complement(573443..574120)
                     /gene="cmk"
                     /locus_tag="COSY_0548"
                     /db_xref="GeneID:5172535"
     CDS             complement(573443..574120)
                     /gene="cmk"
                     /locus_tag="COSY_0548"
                     /EC_number="2.7.4.14"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase"
                     /protein_id="YP_001219389.1"
                     /db_xref="GI:148244695"
                     /db_xref="GeneID:5172535"
                     /translation="MSQNIIPVLTIDGPSGVGKGTIARIMAQKKNWHLLDSGAIYRAF
                     ALTIDTREINIADEKALRKIAETLDVKFKTKSGNKLVSIYLDGKDVSKILRTEKIGKM
                     ASKIASIEVVRAMLLKRQKDFSETPGLVADGRDMGTTVFPDALFKVYLTASVDERVNR
                     RLKQLQAQGSEGIILNILSDVVDRDKRDYTRKYSPLKPAKDALIIDSTKLSIDEVIIQ
                     VIALVEA"
     misc_feature    complement(573446..574102)
                     /gene="cmk"
                     /locus_tag="COSY_0548"
                     /note="cytidylate kinase; Provisional; Region: cmk;
                     PRK00023"
                     /db_xref="CDD:234579"
     misc_feature    complement(573497..574099)
                     /gene="cmk"
                     /locus_tag="COSY_0548"
                     /note="Cytidine monophosphate kinase (CMPK) catalyzes the
                     reversible phosphorylation of cytidine monophosphate (CMP)
                     to produce cytidine diphosphate (CDP), using ATP as the
                     preferred phosphoryl donor; Region: CMPK; cd02020"
                     /db_xref="CDD:238978"
     misc_feature    complement(order(573548..573550,573716..573721,
                     573782..573784))
                     /gene="cmk"
                     /locus_tag="COSY_0548"
                     /note="CMP-binding site; other site"
                     /db_xref="CDD:238978"
     misc_feature    complement(order(573557..573559,573569..573571))
                     /gene="cmk"
                     /locus_tag="COSY_0548"
                     /note="The sites determining sugar specificity; other
                     site"
                     /db_xref="CDD:238978"
     gene            complement(574394..575884)
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /db_xref="GeneID:5172120"
     CDS             complement(574394..575884)
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /EC_number="6.1.1.6"
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase, class II"
                     /protein_id="YP_001219390.1"
                     /db_xref="GI:148244696"
                     /db_xref="GeneID:5172120"
                     /translation="MRDEDNNKLILKRKSKLALLREVGNPFINNFKPENLAQNIIQEF
                     KGFSKEELEKKNMQVSIAGRMMLKRVMGKVSFVHVQDSSGKIQLFVTCDKLPESFYNE
                     QFKKWDIGDIIGAIGILFKTNMGELSIRIDDIKLLTKSLRPLPGKFHGLSDQEIRYRQ
                     RYVDLIMNKTSRNTFKRRSQIINYIRNFFNHHDFIEVETPMLQTIPGGATAKPFETYH
                     NALDMPMYFRISPELYLKRLIIGGMNKVFEINRNFRNEGLSTRHNPEFTMIEFYQAYG
                     TYHDLMNLTEKLFRSIALDVCGSANVYYQGNNLDFFKSFKRISVVDSILQYNPSLIAT
                     DLNQKNAKQTAEKLGIQIKENWGLGKIQIEIFETTVEEKLLQPTFITEYPTEVSPLAR
                     RNDDNPFITDRFELFISGCEIANGFSELNDAQDQAERFKKQVEEKDLGNDESMYYDAD
                     YIRALEYGMPPTAGEGIGIDRLVMLFTDSPSIRDVILFPHMRAEVK"
     misc_feature    complement(574403..575875)
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /note="lysyl-tRNA synthetase; Reviewed; Region: lysS;
                     PRK00484"
                     /db_xref="CDD:234778"
     misc_feature    complement(575390..575713)
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /note="LysRS_N: N-terminal, anticodon recognition domain
                     of lysyl-tRNA synthetases (LysRS). These enzymes are
                     homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs).
                     This domain is a beta-barrel domain (OB fold) involved in
                     binding the tRNA anticodon stem-loop; Region: LysRS_N;
                     cd04322"
                     /db_xref="CDD:239817"
     misc_feature    complement(order(575456..575464,575471..575473,
                     575549..575551,575639..575644,575693..575698))
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239817"
     misc_feature    complement(order(575501..575503,575519..575521,
                     575561..575563,575618..575620,575624..575626,
                     575657..575659,575675..575680,575684..575686))
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /note="putative anticodon binding site; other site"
                     /db_xref="CDD:239817"
     misc_feature    complement(574409..575383)
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /note="Lys_tRNA synthetase (LysRS) class II core domain.
                     Class II LysRS is a dimer which attaches a lysine to the
                     3&apos; OH group of ribose of the appropriate tRNA. Its
                     assignment to class II aaRS is based upon its structure
                     and the presence of three...; Region: LysRS_core; cd00775"
                     /db_xref="CDD:238398"
     misc_feature    complement(575273..575287)
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /note="motif 1; other site"
                     /db_xref="CDD:238398"
     misc_feature    complement(order(574472..574474,574628..574630,
                     574640..574642,574649..574651,574670..574672,
                     575087..575089,575099..575101,575117..575119,
                     575123..575125,575189..575191))
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /note="active site"
                     /db_xref="CDD:238398"
     misc_feature    complement(575117..575128)
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /note="motif 2; other site"
                     /db_xref="CDD:238398"
     misc_feature    complement(574472..574483)
                     /gene="lysS"
                     /locus_tag="COSY_0549"
                     /note="motif 3; other site"
                     /db_xref="CDD:238398"
     gene            complement(576514..576948)
                     /gene="ccmH"
                     /locus_tag="COSY_0550"
                     /db_xref="GeneID:5172243"
     CDS             complement(576514..576948)
                     /gene="ccmH"
                     /locus_tag="COSY_0550"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis protein CcmH"
                     /protein_id="YP_001219391.1"
                     /db_xref="GI:148244697"
                     /db_xref="GeneID:5172243"
                     /translation="MLFYSILFLLGFVSYTHVDSFEAKSYVNNQQQRYQTLINEIRCP
                     VCQGQSIGGSNAGLAKDLREKVMELILEENTDNDIRQFMTDRYGDFVVFKPPVNKNTY
                     LLWFAPFIFLVLGLFFLVRSLLTKESSVKSNIDTTKAKDLLK"
     misc_feature    complement(<576625..576933)
                     /gene="ccmH"
                     /locus_tag="COSY_0550"
                     /note="Cytochrome C biogenesis protein; Region: CcmH;
                     pfam03918"
                     /db_xref="CDD:217792"
     gene            576987..578603
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /db_xref="GeneID:5172031"
     CDS             576987..578603
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="YP_001219392.1"
                     /db_xref="GI:148244698"
                     /db_xref="GeneID:5172031"
                     /translation="MPLITLDNISLSFSDKQILNKVNSTIYKGDKIALIGRNGEGKST
                     FMRILAGLIESDDGKLNIKNGSKISYLEQTLPQNNDKNLFDIVAEGLGDIGIILTEYQ
                     HLINNGKLEQASKVQEKIDQSNSWQYLYKIQTILNRFTLNANTILSTLSSGWKRRVML
                     ARALIQNPDVLLLDEPTNHMDITTILNLEHMLKNYNGTLVLISHDRSFIKSIVNRVFD
                     LDRGNLAVFNCSYVNYVKRKNIQLHTEKIANARFDKKLAQEENWIRQGIKARRTRNEG
                     RIRTLKSMRKSFTNRRVKKSNANIHILNDENHISKLIFEIKKINYQIAGINLIENFSM
                     LILKGEKIGITGSNGTGKSTFIELLLDKLQPDSGSILRSKTIKLAYFDQTQYLEPSMK
                     VMDFASEGREHIDIGGKSKHIIGYLRQFLFTEKQAMAPIRMLSGGEKNRLMLAKILSQ
                     PANLLVLDEPTNDLDIETLELLEEMLVNYNGTLLLISHDRTFLNNVVSSTIVMNDGII
                     NQYAGGYDDYLTKKQDKLYKTKVKTTKKFK"
     misc_feature    576987..578552
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="ATPase components of ABC transporters with
                     duplicated ATPase domains [General function prediction
                     only]; Region: Uup; COG0488"
                     /db_xref="CDD:223562"
     misc_feature    577002..577661
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    577092..577115
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(577101..577106,577110..577118,577203..577205,
                     577506..577511,577596..577598)
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    577194..577205
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    577434..577463
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    577494..577511
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    577518..577529
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    577584..577604
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     misc_feature    577635..577844
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="ABC transporter; Region: ABC_tran_2; pfam12848"
                     /db_xref="CDD:221805"
     misc_feature    577929..578504
                     /gene="uup"
                     /locus_tag="COSY_0551"
                     /note="ATP-binding cassette domain of elongation factor 3,
                     subfamily F; Region: ABCF_EF-3; cd03221"
                     /db_xref="CDD:213188"
     gene            578739..579359
                     /locus_tag="COSY_0552"
                     /db_xref="GeneID:5171832"
     CDS             578739..579359
                     /locus_tag="COSY_0552"
                     /note="Similar to the N-terminal region of UbiA
                     prenyltransferase (483 aa) TR:Q4ZU26 in Pseudomonas
                     syringae pv. syringae."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219393.1"
                     /db_xref="GI:148244699"
                     /db_xref="GeneID:5171832"
                     /translation="MTPLIVDLDHTLIDTDLLYESSIGTLKKNPLLIFIYPFWFFRGK
                     GYLKEQLAKRFPIDIKVLAYNQDVINYIKERKEQGDKIILATASHKLYASAVNNHLKT
                     EKTQIKNKQKNFNFFIHNDQQTTVNKINLFDDVMASNKNFNLSSHNKAKRLIERFGNK
                     GFDYIGDHMRDLPVWEASNLSILVNVPNKIINKTKHLNTLVLSRKN"
     misc_feature    578793..>579317
                     /locus_tag="COSY_0552"
                     /note="hypothetical protein; Validated; Region: PRK08238"
                     /db_xref="CDD:236195"
     gene            580876..581526
                     /locus_tag="COSY_0553"
                     /db_xref="GeneID:5172671"
     CDS             580876..581526
                     /locus_tag="COSY_0553"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219394.1"
                     /db_xref="GI:148244700"
                     /db_xref="GeneID:5172671"
                     /translation="MIKTLLIVLSILPINSTLAIDKVLNTTHQAIVDMIDPPNSAALN
                     IMVSALTSLKELKKQKRATKKNIEALTRLKILPNIAISVSTKIALNKYWDNLNIQQKQ
                     FFKYYISESLIQDYVGILSSYDKLDSVHISVDPDVKRKNDKAIVRLIININNDPKPSI
                     ISLKMIRFNTWRVYDIVFSGISIVKNYRAQFNSYIRRKGIDSLIRKSKQKLKKIAE"
     misc_feature    581020..581505
                     /locus_tag="COSY_0553"
                     /note="Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2;
                     pfam05494"
                     /db_xref="CDD:218607"
     gene            581526..582785
                     /gene="murA"
                     /locus_tag="COSY_0554"
                     /db_xref="GeneID:5172291"
     CDS             581526..582785
                     /gene="murA"
                     /locus_tag="COSY_0554"
                     /EC_number="2.5.1.7"
                     /note="adds enolpyruvyl to UDP-N-acetylglucosamine as a
                     component of cell wall formation; gram-positive bacteria
                     have 2 copies of MurA which are active"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="YP_001219395.1"
                     /db_xref="GI:148244701"
                     /db_xref="GeneID:5172291"
                     /translation="MYKLIIHGGISLNGSVITAGSKNSSLPILFASILANGPITLTNT
                     PHLSDVSTTLRLLMDMGAEFILESDNSLFINGSKLTNLVAQYNLVKTMRASILALGPM
                     LAKYGKAKISLPGGCAIGPRPVNLHLEALENLGATIKVKNGYIYATAKELIGTKIHFK
                     QISVTATENIIMAATLATGITTIYNAAQEPEIVDLVKCLIKMGAIISGAGTSIIIIQG
                     VDELSGVTYSVCPDRIEAGTYLVATAITGGKITIKNVHYQSMHAILEKLLETGADIKT
                     NKNSIILDMKGKRPRAVNIKTSTYPNFPTDMQAQFTALNAIADGYSTITETIFENRFM
                     HIPELSRMGANLVLKGNTVVCKGVKYLTGMPLIATDLRASASLVLAGLVATGTTTIER
                     VYHLDRGYETIEEKLKLLGAQIERVQD"
     misc_feature    581526..582773
                     /gene="murA"
                     /locus_tag="COSY_0554"
                     /note="UDP-N-acetylglucosamine 1-carboxyvinyltransferase;
                     Region: murA; TIGR01072"
                     /db_xref="CDD:162190"
     misc_feature    581559..582755
                     /gene="murA"
                     /locus_tag="COSY_0554"
                     /note="UDP-N-acetylglucosamine enolpyruvyl transferase
                     catalyzes enolpyruvyl transfer as part of the first step
                     in the biosynthesis of peptidoglycan, a component of the
                     bacterial cell wall. The reaction is phosphoenolpyruvate +
                     UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555"
                     /db_xref="CDD:238796"
     misc_feature    order(581577..581588,582210..582221)
                     /gene="murA"
                     /locus_tag="COSY_0554"
                     /note="hinge; other site"
                     /db_xref="CDD:238796"
     misc_feature    order(581592..581594,581802..581804,581814..581816,
                     581889..581906,582006..582008,582015..582020,
                     582441..582443)
                     /gene="murA"
                     /locus_tag="COSY_0554"
                     /note="active site"
                     /db_xref="CDD:238796"
     gene            582792..583409
                     /gene="hisG"
                     /locus_tag="COSY_0555"
                     /db_xref="GeneID:5172293"
     CDS             582792..583409
                     /gene="hisG"
                     /locus_tag="COSY_0555"
                     /EC_number="2.4.2.17"
                     /note="short form of enzyme; requires HisZ for function;
                     catalyzes the formation of N'-5'-phosphoribosyl-ATP from
                     phosphoribosyl pyrophosphate; crucial role in histidine
                     biosynthesis; forms heteromultimer of HisG and HisZ"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase catalytic subunit"
                     /protein_id="YP_001219396.1"
                     /db_xref="GI:148244702"
                     /db_xref="GeneID:5172293"
                     /translation="MLTITLSKGRILKQTLPLLEQAGLIIAKQELNSRKLILDTNLTD
                     VKVIIVRSTDVPVFVQHGATDMGIAGKDVLLEHGANNLFEVLDLGIAKCKLMVAAESK
                     NRLKQNTLKVATKYVNSTKRYFQNKGQSCEIIKLYGAMELAPKVGLAHCIVDLVDTGN
                     TLKANGLIPFEYIEKISSRLVVNVASFRTKNAQIKSWIQNIENSL"
     misc_feature    582792..>583406
                     /gene="hisG"
                     /locus_tag="COSY_0555"
                     /note="ATP phosphoribosyltransferase [Amino acid transport
                     and metabolism]; Region: HisG; COG0040"
                     /db_xref="CDD:223118"
     misc_feature    582792..583406
                     /gene="hisG"
                     /locus_tag="COSY_0555"
                     /note="ATP phosphoribosyltransferase catalytic subunit;
                     Reviewed; Region: hisG; PRK01686"
                     /db_xref="CDD:234971"
     gene            583406..584701
                     /gene="hisD"
                     /locus_tag="COSY_0556"
                     /db_xref="GeneID:5172624"
     CDS             583406..584701
                     /gene="hisD"
                     /locus_tag="COSY_0556"
                     /EC_number="1.1.1.23"
                     /note="catalyzes the oxidation of L-histidinol to
                     L-histidinaldehyde and then to L-histidine in histidine
                     biosynthesis; functions as a dimer"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="YP_001219397.1"
                     /db_xref="GI:148244703"
                     /db_xref="GeneID:5172624"
                     /translation="MITKLVSTQFDFQKKLSSLLEWENVSNSSVTKTVSDIITNIRSN
                     GDSALIDYTNKFDNVNASSMKDLTIELPRLKQAFDILDEKQKSALSTAANRIRLYHEK
                     QKQSTWSYTEDDGTVLGQKITSLDCVGLYVPGGKAVYPSSVLMNAIPAKVAGVKALIM
                     VVPTPNAISNSLILAAAHISGITQVFTIGGAQAIASLAYGTQTIPKVDKIVGPGNIYV
                     ATAKRAVFGQVGIDMIAGPSEILIICDGKTNPDWIAMDLFSQAEHDENSQSLLLSPDS
                     NFINQVESSIKKLLPTMSRKNIIKTALKNRGALIHTKDMNEAISLSNQIAPEHLELSI
                     EHPKAVLDNIKHAGAIFMGRHTCESLGDYCAGPNHVLPTSGTARFSSPLGVYDFQKKS
                     SLIMVSNQGANTLGKITVTLANGEGLQAHAQSARYRITQ"
     misc_feature    583511..584689
                     /gene="hisD"
                     /locus_tag="COSY_0556"
                     /note="Histidinol dehydrogenase [Amino acid transport and
                     metabolism]; Region: HisD; COG0141"
                     /db_xref="CDD:223219"
     misc_feature    583511..584668
                     /gene="hisD"
                     /locus_tag="COSY_0556"
                     /note="Histidinol dehydrogenase, HisD, E.C 1.1.1.23.
                     Histidinol dehydrogenase catalyzes the last two steps in
                     the L-histidine biosynthesis pathway, which is conserved
                     in bacteria, archaea, fungi, and plants. These last two
                     steps are (i) the NAD-dependent...; Region: Histidinol_dh;
                     cd06572"
                     /db_xref="CDD:119329"
     misc_feature    order(583571..583573,583796..583798,583802..583807,
                     583829..583831,583892..583894,583970..583975,
                     583979..583981,584042..584050,584054..584059,
                     584192..584194)
                     /gene="hisD"
                     /locus_tag="COSY_0556"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:119329"
     misc_feature    order(583655..583660,583667..583672,583676..583678,
                     583685..583690,583697..583702,583709..583714,
                     583733..583735,583739..583741,583751..583765,
                     583772..583774,583778..583780,583814..583828,
                     584027..584029,584072..584074,584084..584086,
                     584156..584161,584168..584173,584177..584185,
                     584189..584194,584402..584404,584417..584419,
                     584426..584431,584435..584461,584465..584467,
                     584471..584476,584480..584494,584498..584500,
                     584504..584506,584534..584539,584543..584557,
                     584561..584566,584573..584596,584639..584644,
                     584648..584668)
                     /gene="hisD"
                     /locus_tag="COSY_0556"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:119329"
     misc_feature    order(583820..583822,583826..583828,584117..584119,
                     584192..584194,584387..584392,584477..584479,
                     584489..584494,584510..584512,584651..584653,
                     584657..584659,584666..584668)
                     /gene="hisD"
                     /locus_tag="COSY_0556"
                     /note="product binding site; other site"
                     /db_xref="CDD:119329"
     misc_feature    order(583826..583828,584117..584119,584183..584185,
                     584192..584194,584387..584392,584477..584479,
                     584489..584494,584510..584512,584651..584653,
                     584657..584659,584666..584668)
                     /gene="hisD"
                     /locus_tag="COSY_0556"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:119329"
     misc_feature    order(584183..584185,584192..584194,584489..584491,
                     584666..584668)
                     /gene="hisD"
                     /locus_tag="COSY_0556"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:119329"
     misc_feature    584387..584392
                     /gene="hisD"
                     /locus_tag="COSY_0556"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:119329"
     gene            complement(584810..586210)
                     /gene="ffh"
                     /locus_tag="COSY_0557"
                     /db_xref="GeneID:5172721"
     CDS             complement(584810..586210)
                     /gene="ffh"
                     /locus_tag="COSY_0557"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle, subunit SRP54"
                     /protein_id="YP_001219398.1"
                     /db_xref="GI:148244704"
                     /db_xref="GeneID:5172721"
                     /translation="MFDNLTELLQNSFKVLQGKNKLSESNVKEAIRKVRRALLEADVA
                     LEVIKVFLDKVQIKALGLKVGQGLTPSQTFIKLVETELTKIIGGKVESLDLKTQPPAI
                     IMVAGLQGAGKTTSVAKIAFYLKQRENKKVLVVSADVYRPAAIEQLEVLSKQIEVDFF
                     PSTINDKPSDIVANAKRYAQKQFFDVLLVDTAGRLHIDEQMMNEIKILQKKVDPIETL
                     FVIDSMTGQDAVHTAKVFSNALPLTGVILTKTDGDARGGAALSVRHIIGKPIKFLGVG
                     EKIDALELFHPERVVSRLLGMGDVLSLVEEISRKVNHKKVQKSFQKMTKGQFDLSDMR
                     YQLLQTEKMGGIEAMMNKLPGLGKIPQNVKNQIVNGAEIKKMVAIINSMTPKERSYIS
                     LIKGSRKARIANGSGTNIQAVNKLIKQFEKMQKQMKKVSGGKMQKMMAKMVDSDGMPD
                     FSKIKKSNISSNKFPF"
     misc_feature    complement(584864..586210)
                     /gene="ffh"
                     /locus_tag="COSY_0557"
                     /note="signal recognition particle protein; Provisional;
                     Region: PRK10867"
                     /db_xref="CDD:236780"
     misc_feature    complement(585956..586186)
                     /gene="ffh"
                     /locus_tag="COSY_0557"
                     /note="SRP54-type protein, helical bundle domain; Region:
                     SRP54_N; smart00963"
                     /db_xref="CDD:214941"
     misc_feature    complement(585389..585910)
                     /gene="ffh"
                     /locus_tag="COSY_0557"
                     /note="The signal recognition particle (SRP) mediates the
                     transport to or across the plasma membrane in bacteria and
                     the endoplasmic reticulum in eukaryotes. SRP recognizes
                     N-terminal sighnal sequences of newly synthesized
                     polypeptides at the ribosome. The...; Region: SRP;
                     cd03115"
                     /db_xref="CDD:239389"
     misc_feature    complement(585869..585892)
                     /gene="ffh"
                     /locus_tag="COSY_0557"
                     /note="P loop; other site"
                     /db_xref="CDD:239389"
     misc_feature    complement(order(585455..585460,585467..585469,
                     585632..585634,585797..585799))
                     /gene="ffh"
                     /locus_tag="COSY_0557"
                     /note="GTP binding site [chemical binding]; other site"
                     /db_xref="CDD:239389"
     misc_feature    complement(584894..585232)
                     /gene="ffh"
                     /locus_tag="COSY_0557"
                     /note="Signal peptide binding domain; Region: SRP_SPB;
                     pfam02978"
                     /db_xref="CDD:202493"
     gene            586273..587052
                     /locus_tag="COSY_0558"
                     /db_xref="GeneID:5172001"
     CDS             586273..587052
                     /locus_tag="COSY_0558"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c assembly family protein"
                     /protein_id="YP_001219399.1"
                     /db_xref="GI:148244705"
                     /db_xref="GeneID:5172001"
                     /translation="MLLSYLAIALYFAATFLLIRYFVINEIQHQQTIFLLVSLAIIVQ
                     SLTFSHFWSDKGIVFGLANSASFVAWLISVLLFLSSLSKPVHVLGILIYPLVAFTLAF
                     SIAFPDTINKVIPINIALHVLLSITAYALLALAVCQSVLLNIQEKHLHARKINSFINK
                     LPALQTIEALLFQILRIGFYLLTLSLLSGFIFVQDIFSQHLIHKTTLSIIAWIIFAIL
                     VFGRKVFGWRGKQAITSTQFGFGILVIAYFGSKFVLERLLT"
     misc_feature    <586432..587046
                     /locus_tag="COSY_0558"
                     /note="Cytochrome C assembly protein; Region:
                     Cytochrom_C_asm; cl00504"
                     /db_xref="CDD:241908"
     gene            complement(587509..589296)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /db_xref="GeneID:5171904"
     CDS             complement(587509..589296)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="binds to the ribosome on the universally-conserved
                     alpha-sarcin loop"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein LepA"
                     /protein_id="YP_001219400.1"
                     /db_xref="GI:148244706"
                     /db_xref="GeneID:5171904"
                     /translation="MKNIRNFSIIAHIDHGKSTIADCFIQFCGGLSDREMSSQVLDSM
                     DIEKERGITIKSQSVTLDYHAKNGETYQLNFIDTPGHVDFSYEVSRSLSACEGALLIV
                     DASQGVEAQTVANCYTALEQGLQVVSVLNKIDLPAADPERVMDEIEDVIGVEAHDVVH
                     ASAKLGIGIEDILEQIVERIPTPKGNINAPIKALIIDSWFDSYLGVVSLIRMIDGEIK
                     IKTKIKIFSNGGEYIVDEVGIFTPKRKRIDSLKAGEVGFLIANIKNIDGAPVGDTITS
                     AENPASESLEGFRPVQPCVFAGIFPISGKDYEKFRDALAKLRLNDAALQYEPENSDVL
                     GFGFRIGFLGLLHMEIVQERLEREYDLDLIITAPTVIYEILDTKGIIHRVDSLSKMPT
                     NQSISKFREPIITAKILVISKYVGAVMNLCIEKRGIQKNIIYMSRQVSLIYELPLNEV
                     VLDFFDRLKSVSRGFASMDYHFERYQESDLICLDVMINQEPVDALALIMHRDDSVRKG
                     NELVEKMKELIPRQMFDVTIQACIGSKIISRSNVKALRKNVTAKCYGGDVSRKKKLLD
                     KQNKGKKRMRSVGRVDIPKEVFLAILHIN"
     misc_feature    complement(587512..589296)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="GTP-binding protein LepA; Provisional; Region:
                     PRK05433"
                     /db_xref="CDD:235462"
     misc_feature    complement(588748..589284)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="LepA also known as Elongation Factor 4 (EF4);
                     Region: LepA; cd01890"
                     /db_xref="CDD:206677"
     misc_feature    complement(589243..589266)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="G1 box; other site"
                     /db_xref="CDD:206677"
     misc_feature    complement(order(588859..588861,588871..588873,
                     588979..588984,589051..589056,589123..589128,
                     589219..589224,589231..589233,589240..589245,
                     589255..589257,589261..589263))
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="putative GEF interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:206677"
     misc_feature    complement(order(588805..588813,588895..588897,
                     588901..588906,589240..589257))
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206677"
     misc_feature    complement(589126..589161)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206677"
     misc_feature    complement(589138..589140)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="G2 box; other site"
                     /db_xref="CDD:206677"
     misc_feature    complement(589057..589068)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="G3 box; other site"
                     /db_xref="CDD:206677"
     misc_feature    complement(589006..589062)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206677"
     misc_feature    complement(588895..588906)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="G4 box; other site"
                     /db_xref="CDD:206677"
     misc_feature    complement(588805..588813)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="G5 box; other site"
                     /db_xref="CDD:206677"
     misc_feature    complement(588469..588723)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="lepA_II: This subfamily represents the domain II of
                     LepA, a GTP-binding protein localized in the cytoplasmic
                     membrane. The N-terminal domain of LepA shares regions of
                     homology to translation factors. In terms of interaction
                     with the ribosome, EF-G, EF-Tu...; Region: lepA_II;
                     cd03699"
                     /db_xref="CDD:239670"
     misc_feature    complement(587860..588096)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="lepA_C: This family represents the C-terminal
                     region of LepA, a GTP-binding protein localized in the
                     cytoplasmic membrane.   LepA is ubiquitous in Bacteria and
                     Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is
                     missing from Archaea. LepA exhibits...; Region: lepA_C;
                     cd03709"
                     /db_xref="CDD:239680"
     misc_feature    complement(587515..587838)
                     /gene="lepA"
                     /locus_tag="COSY_0559"
                     /note="GTP-binding protein LepA C-terminus; Region:
                     LepA_C; pfam06421"
                     /db_xref="CDD:203441"
     gene            589337..589786
                     /locus_tag="COSY_0560"
                     /db_xref="GeneID:5172648"
     CDS             589337..589786
                     /locus_tag="COSY_0560"
                     /note="bacterioferritin comigratory protein Bcp"
                     /codon_start=1
                     /transl_table=11
                     /product="AhpC/TSA family peroxiredoxin"
                     /protein_id="YP_001219401.1"
                     /db_xref="GI:148244707"
                     /db_xref="GeneID:5172648"
                     /translation="MNKVQPITCTATSNLKISIPDTKGRNIVLYFYPKDSTPGCITEG
                     QNFRDKHQAFLDANTVIYGVSKDDLTKHEKFKAKQNFPFELIVDINGTLCELFNVWQL
                     KKFIGREYMGIVRSTFLIDANGNILKHWDKVKVKGHVEEVLIFTQAL"
     misc_feature    589343..>589723
                     /locus_tag="COSY_0560"
                     /note="Peroxiredoxin [Posttranslational modification,
                     protein turnover, chaperones]; Region: AhpC; COG0450"
                     /db_xref="CDD:223527"
     misc_feature    589355..589765
                     /locus_tag="COSY_0560"
                     /note="Peroxiredoxin (PRX) family, Bacterioferritin
                     comigratory protein (BCP) subfamily; composed of
                     thioredoxin-dependent thiol peroxidases, widely expressed
                     in pathogenic bacteria, that protect cells against
                     toxicity from reactive oxygen species by reducing...;
                     Region: PRX_BCP; cd03017"
                     /db_xref="CDD:239315"
     misc_feature    order(589445..589447,589454..589456,589679..589681)
                     /locus_tag="COSY_0560"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:239315"
     gene            589783..590481
                     /gene="ubiG"
                     /locus_tag="COSY_0561"
                     /db_xref="GeneID:5171977"
     CDS             589783..590481
                     /gene="ubiG"
                     /locus_tag="COSY_0561"
                     /EC_number="2.1.1.64"
                     /codon_start=1
                     /transl_table=11
                     /product="3-demethylubiquinone-9 3-methyltransferase"
                     /protein_id="YP_001219402.1"
                     /db_xref="GI:148244708"
                     /db_xref="GeneID:5171977"
                     /translation="MNNIDFNEVNKFATLASHWWDKNSKFKPLHDINPLRLNYIKQQH
                     NCPLKDKQILDIGCGGGILTESFALEGAVVTGIDMAEEGLEVAKLHLLESGLKVDYQK
                     IYVEKFARQNTKKFDIITCLEMLEHVPDPGSIIKACGELVKPGGQVFFSTINRNAKSY
                     LFAIIGAEYILKLLPQGTHDWNKFIQPSEIDKWARASSLSLKGMTGIVYNPFTKTYKL
                     KDDVSVNYLSHYQK"
     misc_feature    589783..590478
                     /gene="ubiG"
                     /locus_tag="COSY_0561"
                     /note="bifunctional 3-demethylubiquinone-9
                     3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol
                     methylase; Provisional; Region: PRK05134"
                     /db_xref="CDD:235350"
     misc_feature    589939..590235
                     /gene="ubiG"
                     /locus_tag="COSY_0561"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(589948..589968,590014..590019,590089..590097,
                     590146..590148)
                     /gene="ubiG"
                     /locus_tag="COSY_0561"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            590517..590822
                     /locus_tag="COSY_0562"
                     /db_xref="GeneID:5171854"
     CDS             590517..590822
                     /locus_tag="COSY_0562"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219403.1"
                     /db_xref="GI:148244709"
                     /db_xref="GeneID:5171854"
                     /translation="MKIILTLLFLTSNFSALALSPNEMLVIVGAVKYYNENCSGLNSA
                     GFQRMNKGLKRFKMNKIPIPILEQQLLAISSYQTAKKFGCIKTKNEAYKAGFGQYIN"
     gene            complement(590819..591202)
                     /gene="acpS"
                     /locus_tag="COSY_0563"
                     /db_xref="GeneID:5172603"
     CDS             complement(590819..591202)
                     /gene="acpS"
                     /locus_tag="COSY_0563"
                     /EC_number="2.7.8.7"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-[acyl-carrier protein] synthase"
                     /protein_id="YP_001219404.1"
                     /db_xref="GI:148244710"
                     /db_xref="GeneID:5172603"
                     /translation="MIYGVGVDIVNIERVERILSKNKEGFVKRVLSEYEQVLFAKKGD
                     SSTYCAKRFSAKEAFAKALGIGIGKIVSFQDLTICNNKQGNPYFIFSAKLCLYLVDKN
                     IKKAHLSLSDEKFNAMAFVILEIEN"
     misc_feature    complement(590831..591202)
                     /gene="acpS"
                     /locus_tag="COSY_0563"
                     /note="4&apos;-phosphopantetheinyl transferase;
                     Provisional; Region: acpS; PRK00070"
                     /db_xref="CDD:234610"
     gene            complement(591199..591924)
                     /gene="pdxJ"
                     /locus_tag="COSY_0564"
                     /db_xref="GeneID:5171855"
     CDS             complement(591199..591924)
                     /gene="pdxJ"
                     /locus_tag="COSY_0564"
                     /note="involved in the de novo synthesis of pyridoxine
                     (Vitamin B6)"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="YP_001219405.1"
                     /db_xref="GI:148244711"
                     /db_xref="GeneID:5171855"
                     /translation="MGIYLGINIDHIATIRQVRGTDYPSLVEAALLCEKSGADSITLH
                     LREDRRHIQDADVEILRGKLTTKMNLEMAATDEMIAIASKIKPQNCCLVPEKREELTT
                     EGGLNVTSQISKICDICIQLKMSNIIVSLFIDAQKDQIDAAKQCGAAVVELHTGHYAN
                     ATNEAQLTELERIKIMATYARSIGLQVNAGHGLTLGNITNIAKLPEIVELNIGHSIIS
                     RAIFVSLGTAIQEMKNLMIDARQ"
     misc_feature    complement(591217..591912)
                     /gene="pdxJ"
                     /locus_tag="COSY_0564"
                     /note="Pyridoxine 5&apos;-phosphate (PNP) synthase domain;
                     pyridoxal 5&apos;-phosphate is the active form of vitamin
                     B6 that acts as an essential, ubiquitous coenzyme in amino
                     acid metabolism. In bacteria, formation of pyridoxine
                     5&apos;-phosphate is a step in...; Region: PNPsynthase;
                     cd00003"
                     /db_xref="CDD:237977"
     misc_feature    complement(order(591283..591288,591349..591354,
                     591469..591471,591529..591531,591610..591612,
                     591619..591624,591712..591714,591772..591777,
                     591787..591789,591793..591795,591868..591870,
                     591892..591897,591901..591903))
                     /gene="pdxJ"
                     /locus_tag="COSY_0564"
                     /note="active site"
                     /db_xref="CDD:237977"
     misc_feature    complement(order(591292..591294,591298..591303,
                     591352..591354,591361..591363,591469..591471,
                     591475..591477,591529..591531,591535..591537,
                     591652..591654,591658..591660,591712..591714,
                     591718..591720,591724..591726,591799..591801,
                     591901..591903))
                     /gene="pdxJ"
                     /locus_tag="COSY_0564"
                     /note="hydrophilic channel; other site"
                     /db_xref="CDD:237977"
     misc_feature    complement(order(591445..591450,591868..591870))
                     /gene="pdxJ"
                     /locus_tag="COSY_0564"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:237977"
     misc_feature    complement(order(591352..591354,591469..591471,
                     591712..591714,591793..591795))
                     /gene="pdxJ"
                     /locus_tag="COSY_0564"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:237977"
     misc_feature    complement(591610..591642)
                     /gene="pdxJ"
                     /locus_tag="COSY_0564"
                     /note="active site lid [active]"
                     /db_xref="CDD:237977"
     gene            complement(592352..593302)
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /db_xref="GeneID:5171866"
     CDS             complement(592352..593302)
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein Era"
                     /protein_id="YP_001219406.1"
                     /db_xref="GI:148244712"
                     /db_xref="GeneID:5171866"
                     /translation="MCTNFIKKIKKIMIKINNKITKSNFKSGFIGVVGRPNVGKSTLI
                     NELIGRKLSITSHRPQTTRHRIHAIDTTDNYQMVFVDTPGIHMGNYKAINSYMNRVAS
                     LAIMDVDVILWLIEVGKWTKEDLRVLEHITQIDVPVILCINKIDKLKSPQEVLPFLNK
                     IFQKYQPTDLFPLSAFKKNDICVLRELVLQYLPKQTLIFDADYITDRSEKFIVAEFIR
                     EKLMRHLKDELPYDLTVEIEQFEQDRNLQRIASHIFVDKASQKNIVIGNKGVMLKLIG
                     TEARKSIEGFLDRKVFLKLRVKVKQGWSDDKRALASLGYD"
     misc_feature    complement(592358..593221)
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="GTPase Era; Reviewed; Region: era; PRK00089"
                     /db_xref="CDD:234624"
     misc_feature    complement(592727..593221)
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="E. coli Ras-like protein (Era) is a multifunctional
                     GTPase; Region: Era; cd04163"
                     /db_xref="CDD:206726"
     misc_feature    complement(593180..593203)
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="G1 box; other site"
                     /db_xref="CDD:206726"
     misc_feature    complement(order(592778..592783,592865..592867,
                     592871..592876,593051..593053,593117..593125,
                     593135..593137,593177..593197))
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206726"
     misc_feature    complement(order(593108..593152,593156..593158))
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206726"
     misc_feature    complement(593117..593119)
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="G2 box; other site"
                     /db_xref="CDD:206726"
     misc_feature    complement(order(592982..592987,593048..593065))
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206726"
     misc_feature    complement(593051..593062)
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="G3 box; other site"
                     /db_xref="CDD:206726"
     misc_feature    complement(592865..592876)
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="G4 box; other site"
                     /db_xref="CDD:206726"
     misc_feature    complement(592775..592783)
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="G5 box; other site"
                     /db_xref="CDD:206726"
     misc_feature    complement(<592451..592621)
                     /gene="era"
                     /locus_tag="COSY_0565"
                     /note="KH domain; Region: KH_2; pfam07650"
                     /db_xref="CDD:203707"
     gene            complement(593263..593928)
                     /gene="rnc"
                     /locus_tag="COSY_0566"
                     /db_xref="GeneID:5172471"
     CDS             complement(593263..593928)
                     /gene="rnc"
                     /locus_tag="COSY_0566"
                     /EC_number="3.1.26.3"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="YP_001219407.1"
                     /db_xref="GI:148244713"
                     /db_xref="GeneID:5172471"
                     /translation="MKKLQKKINYQFKDLSLLKLALTHRSTGRNNNERLEFLGDSILG
                     VAISKELYQRFPCVDEGKLSRLRSHLIRGQTLVQLGTALELSNNLILGSGELKSGGYR
                     RESIQADTVEAIFGAVLLDSNFETTNMVILGLFKVLLNSISPDDSLKDSKTQLQEYLQ
                     KRGNILPKYKLIDTTGKDHNAIFMVNCFLEDQKLQVKQSAKSIKKAEQFCAQILLKKL
                     KKS"
     misc_feature    complement(593269..593928)
                     /gene="rnc"
                     /locus_tag="COSY_0566"
                     /note="ribonuclease III; Reviewed; Region: rnc; PRK00102"
                     /db_xref="CDD:234633"
     misc_feature    complement(593497..593883)
                     /gene="rnc"
                     /locus_tag="COSY_0566"
                     /note="RIBOc. Ribonuclease III C terminal domain. This
                     group consists of eukaryotic, bacterial and archeal
                     ribonuclease III (RNAse III) proteins. RNAse III is a
                     double stranded RNA-specific endonuclease. Prokaryotic
                     RNAse III is important in...; Region: RIBOc; cd00593"
                     /db_xref="CDD:238333"
     misc_feature    complement(order(593545..593547,593572..593574,
                     593740..593742,593770..593778,593782..593787,
                     593794..593799,593806..593808,593815..593820,
                     593827..593832))
                     /gene="rnc"
                     /locus_tag="COSY_0566"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238333"
     misc_feature    complement(order(593593..593595,593602..593604,
                     593809..593811,593821..593823,593830..593832))
                     /gene="rnc"
                     /locus_tag="COSY_0566"
                     /note="active site"
                     /db_xref="CDD:238333"
     misc_feature    complement(order(593593..593595,593602..593604,
                     593821..593823))
                     /gene="rnc"
                     /locus_tag="COSY_0566"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:238333"
     misc_feature    complement(593275..593481)
                     /gene="rnc"
                     /locus_tag="COSY_0566"
                     /note="Double-stranded RNA binding motif. Binding is not
                     sequence specific but is highly specific for double
                     stranded RNA. Found in a variety of proteins including
                     dsRNA dependent protein kinase PKR, RNA helicases,
                     Drosophila staufen protein, E. coli RNase III; Region:
                     DSRM; cd00048"
                     /db_xref="CDD:238007"
     misc_feature    complement(order(593308..593310,593317..593328,
                     593458..593463,593479..593481))
                     /gene="rnc"
                     /locus_tag="COSY_0566"
                     /note="dsRNA binding site [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238007"
     gene            593960..594661
                     /locus_tag="COSY_0567"
                     /db_xref="GeneID:5172719"
     CDS             593960..594661
                     /locus_tag="COSY_0567"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219408.1"
                     /db_xref="GI:148244714"
                     /db_xref="GeneID:5172719"
                     /translation="MFIIHSDYNLRFFMFWQEEAKKEHFTLPETIQDVVFNIFSNILP
                     IDHSFLLEQALLKHLPWLNEVDAGIFNISVADGNGWVQNHKNGFYYPSKRSKLIIRLP
                     KDKLNETKQLLGKTLYLDKYEIKIIKFLKPKLLSDIPILFAKKIVCNETMSENDFLQD
                     AFEQLKTLDISVKKMIVGLKNHIKTDTNIIHTRSLMVADLKKYESITLQEKGLGNYRL
                     LGCGLFIPHKDITSI"
     misc_feature    594053..594646
                     /locus_tag="COSY_0567"
                     /note="CRISPR/Cas system-associated RAMP superfamily
                     protein Cas6; Region: Cas6-I-III; cd09733"
                     /db_xref="CDD:187864"
     gene            complement(594979..595773)
                     /gene="thyA"
                     /locus_tag="COSY_0568"
                     /db_xref="GeneID:5172606"
     CDS             complement(594979..595773)
                     /gene="thyA"
                     /locus_tag="COSY_0568"
                     /EC_number="2.1.1.45"
                     /note="ThyA; catalyzes formation of dTMP and
                     7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and
                     dUMP; involved in deoxyribonucleotide biosynthesis; there
                     are 2 copies in some Bacilli, one of which appears to be
                     phage-derived"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="YP_001219409.1"
                     /db_xref="GI:148244715"
                     /db_xref="GeneID:5172606"
                     /translation="MKQYLDFLKLVKNIGVYKTDRTNTGTTSMFGYQMRFDLSKGFPL
                     VTTKHVHLPSVVYELLWFLNGDTNIKYLQDNGVRIWNEWADENGDLGPVYGTQWRHWK
                     NIKDKSIDQISKVVEQIKNTPNSRRIIVSAWNVGELENMALPPCHVFFQFYVADGKLS
                     CQLYQRSADIFLGVPFNIASYSLLTHMMAQQCDLEVGDFIWSGGDCHIYSNHYKQVEI
                     QLSRTPKALATLKIKRKPENIFDYSFEDFEFVNYIFDAPIKAPVAI"
     misc_feature    complement(594982..595773)
                     /gene="thyA"
                     /locus_tag="COSY_0568"
                     /note="thymidylate synthase; Reviewed; Region: thyA;
                     PRK01827"
                     /db_xref="CDD:234984"
     misc_feature    complement(595123..595767)
                     /gene="thyA"
                     /locus_tag="COSY_0568"
                     /note="Thymidylate synthase and pyrimidine
                     hydroxymethylase: Thymidylate synthase (TS) and
                     deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs
                     that catalyze analogous alkylation of C5 of pyrimidine
                     nucleotides. Both enzymes are involved in the...; Region:
                     TS_Pyrimidine_HMase; cd00351"
                     /db_xref="CDD:238211"
     misc_feature    complement(order(595159..595164,595273..595278,
                     595282..595284,595309..595311,595321..595323,
                     595327..595329,595369..595374,595393..595398,
                     595684..595686,595690..595692,595714..595716,
                     595726..595728))
                     /gene="thyA"
                     /locus_tag="COSY_0568"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238211"
     misc_feature    complement(order(595147..595149,595153..595155,
                     595243..595248,595267..595269,595273..595281,
                     595333..595338,595492..595494,595525..595527,
                     595534..595536,595600..595602,595711..595713))
                     /gene="thyA"
                     /locus_tag="COSY_0568"
                     /note="active site"
                     /db_xref="CDD:238211"
     gene            complement(595770..596555)
                     /gene="lgt"
                     /locus_tag="COSY_0569"
                     /db_xref="GeneID:5171838"
     CDS             complement(595770..596555)
                     /gene="lgt"
                     /locus_tag="COSY_0569"
                     /EC_number="2.4.99.-"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="YP_001219410.1"
                     /db_xref="GI:148244716"
                     /db_xref="GeneID:5171838"
                     /translation="MTYPIINPIALDLGFIQIYWYGVMYLMAFLVAYLLANYRVKQKQ
                     LNNWNTQQIEDLIFYGAIGVVSGGRLGYMLFYNFLNFLSDPLLIFAIQDGGMSFHGGF
                     LGVLLAMVLFNRKYNKTFFTTMDFVAPLVPLGLGFGRIGNFINSELWGQITTSPFGMY
                     IEQQSVSRYPSQLVEAFLEGLILFIILWLFSNKLRPSMSISALFLIFYGLFRFIIEFI
                     RLPDVQLGYLAFGWFTMGQLLSLPMILVGIFLLRKAYIKKEIM"
     misc_feature    complement(595782..596555)
                     /gene="lgt"
                     /locus_tag="COSY_0569"
                     /note="prolipoprotein diacylglyceryl transferase;
                     Reviewed; Region: PRK00052"
                     /db_xref="CDD:234599"
     gene            complement(596571..596647)
                     /locus_tag="COSY_t21"
                     /db_xref="GeneID:5329751"
     tRNA            complement(596571..596647)
                     /locus_tag="COSY_t21"
                     /product="tRNA-Arg"
                     /db_xref="GeneID:5329751"
     gene            complement(596667..596978)
                     /locus_tag="COSY_0571"
                     /db_xref="GeneID:5172587"
     CDS             complement(596667..596978)
                     /locus_tag="COSY_0571"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="YP_001219411.1"
                     /db_xref="GI:148244717"
                     /db_xref="GeneID:5172587"
                     /translation="MGEIALLEKEEDIEKATRALKAMAHPLRLKILCALKNDELPVLE
                     IVNKVGSSQSNISQHIDILRTKNIVESRRDGNKILCKIKDTKVLKLVSNIQAVFCSEG
                     V"
     misc_feature    complement(596715..596921)
                     /locus_tag="COSY_0571"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cd00090"
                     /db_xref="CDD:238042"
     misc_feature    complement(order(596715..596720,596778..596780,
                     596868..596870,596877..596882,596889..596894,
                     596901..596903,596910..596912,596916..596921))
                     /locus_tag="COSY_0571"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    complement(order(596739..596747,596760..596768,
                     596784..596789,596793..596798,596805..596810,
                     596814..596825,596850..596858,596895..596903,
                     596913..596918))
                     /locus_tag="COSY_0571"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238042"
     misc_feature    complement(order(596718..596720,596847..596849,
                     596856..596858))
                     /locus_tag="COSY_0571"
                     /note="putative Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238042"
     gene            complement(596985..597569)
                     /locus_tag="COSY_0572"
                     /db_xref="GeneID:5172118"
     CDS             complement(596985..597569)
                     /locus_tag="COSY_0572"
                     /note="Similar to toluene tolerance protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219412.1"
                     /db_xref="GI:148244718"
                     /db_xref="GeneID:5172118"
                     /translation="MRRLNIILLALIMFISLGASAEKVVQDNSGPVQAIQTAIVKLNQ
                     LISMVYSPRMLNSFVEKEIAPLFDFNHIANEAFLVTNNRLSEKETKFFVNRLKDNMMT
                     TLLARLSQVNSTSFQFISARPVMSDAIAVQLKVKRYTSYGGIYLDLLFHQNKDKKWQI
                     FDIIFNNDSLINFYQKMILIKVRRYGIYGMLGRL"
     misc_feature    complement(596988..597416)
                     /locus_tag="COSY_0572"
                     /note="Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2;
                     cl01074"
                     /db_xref="CDD:242286"
     gene            597670..599001
                     /locus_tag="COSY_0573"
                     /db_xref="GeneID:5171912"
     CDS             597670..599001
                     /locus_tag="COSY_0573"
                     /note="peptidase S41A"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxyl-terminal protease"
                     /protein_id="YP_001219413.1"
                     /db_xref="GI:148244719"
                     /db_xref="GeneID:5171912"
                     /translation="MTFLNFLKYSLFLTLFYTTLGVYTPALAKNDTEKQKIEDFFKDL
                     EIFTAVFSNIKKLYVDDVDNKKLFNYAIKGMVSGLDPHSAYLELKEQKSLLESASGKF
                     GGLGIIIGMKDEAIQVISPIDDTPAYKAGIQAGDLIVKINNKAVRGMTLEDSVELMRG
                     KAGTNVQITIVRKNKKPFIVDIIREIITIISVKGYLLEENIGYIRISSFQNPTAQLLK
                     QIFNDLVKENNTQLSSLILDLRNNPGGVLNSAVDVSNLFLDKKGLVVYTKGRIPISNL
                     KFKIKSGDIMQGLPIVVLINEGSASASEIVAGALQDHKRAIIMGTTSFGKGSVQTILE
                     SQKGHGLKLTTARYYTPNGRSIQAKGIVPDIELKNINIQNEVEKSIIETKEKDLDGHL
                     EVENSSKEILSIQKQNKTKQNKIIIKKLEKDYFIHEAKNLLKALTIINNQK"
     misc_feature    597742..598878
                     /locus_tag="COSY_0573"
                     /note="Periplasmic protease [Cell envelope biogenesis,
                     outer membrane]; Region: Prc; COG0793"
                     /db_xref="CDD:223864"
     misc_feature    597787..>597924
                     /locus_tag="COSY_0573"
                     /note="C-terminal processing peptidase family S41; Region:
                     Peptidase_S41; cl02526"
                     /db_xref="CDD:243070"
     misc_feature    597973..598203
                     /locus_tag="COSY_0573"
                     /note="PDZ domain of C-terminal processing-,
                     tail-specific-, and tricorn proteases, which function in
                     posttranslational protein processing, maturation, and
                     disassembly or degradation, in Bacteria, Archaea, and
                     plant chloroplasts. May be responsible for...; Region:
                     PDZ_CTP_protease; cd00988"
                     /db_xref="CDD:238488"
     misc_feature    order(597979..597990,597994..597996,598129..598134,
                     598141..598146)
                     /locus_tag="COSY_0573"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238488"
     misc_feature    <598270..598773
                     /locus_tag="COSY_0573"
                     /note="C-terminal processing peptidase; serine protease
                     family S41; Region: Peptidase_S41_CPP; cd07560"
                     /db_xref="CDD:143476"
     misc_feature    order(598570..598572,598645..598647)
                     /locus_tag="COSY_0573"
                     /note="Catalytic dyad [active]"
                     /db_xref="CDD:143476"
     gene            complement(599452..600336)
                     /gene="lepB"
                     /locus_tag="COSY_0574"
                     /db_xref="GeneID:5172609"
     CDS             complement(599452..600336)
                     /gene="lepB"
                     /locus_tag="COSY_0574"
                     /EC_number="3.4.21.89"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="YP_001219414.1"
                     /db_xref="GI:148244720"
                     /db_xref="GeneID:5172609"
                     /translation="MTIENAASFFAWDVSSFLVLFLVLAFIIVTIDQLFFNHTTISIT
                     SKKKRPTLGRFIYFFLFLRFKKSEKYLNRPKIVQWSAEFFPVLLLVFVLRGFVIEPFR
                     IPSNSMMPTLLTGDFILVSKFNYGVSIPILNKKIIEFSKPERGDVVVFRYPNYENNLR
                     YKGADFIKRVIGIPGDKIVYHVDNLYVNDVKISSENIGIYQGIESGSAMTGFKNKREL
                     LNNNPYNILLDPKHPSKSIKLTVPEEHYFVMGDNRARSSDSRFWGFVPESYIIGKAFG
                     IWMHWDKSLKLDRIGSFD"
     misc_feature    complement(<599818..600042)
                     /gene="lepB"
                     /locus_tag="COSY_0574"
                     /note="The S26 Type I signal peptidase (SPase; LepB;
                     leader peptidase B; leader peptidase I; EC 3.4.21.89)
                     family members are essential membrane-bound serine
                     proteases that function to cleave the amino-terminal
                     signal peptide extension from proteins that are...;
                     Region: S26_SPase_I; cd06530"
                     /db_xref="CDD:119398"
     misc_feature    complement(order(599833..599835,600016..600018))
                     /gene="lepB"
                     /locus_tag="COSY_0574"
                     /note="Catalytic site [active]"
                     /db_xref="CDD:119398"
     misc_feature    complement(599503..599970)
                     /gene="lepB"
                     /locus_tag="COSY_0574"
                     /note="Signal peptidase, peptidase S26; Region:
                     Peptidase_S26; pfam10502"
                     /db_xref="CDD:151062"
     misc_feature    complement(599515..>599601)
                     /gene="lepB"
                     /locus_tag="COSY_0574"
                     /note="The S26 Type I signal peptidase (SPase; LepB;
                     leader peptidase B; leader peptidase I; EC 3.4.21.89)
                     family members are essential membrane-bound serine
                     proteases that function to cleave the amino-terminal
                     signal peptide extension from proteins that are...;
                     Region: S26_SPase_I; cd06530"
                     /db_xref="CDD:119398"
     gene            600392..600733
                     /gene="yccK"
                     /locus_tag="COSY_0575"
                     /db_xref="GeneID:5172515"
     CDS             600392..600733
                     /gene="yccK"
                     /locus_tag="COSY_0575"
                     /EC_number="1.8.99.3"
                     /note="DsrC-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase"
                     /protein_id="YP_001219415.1"
                     /db_xref="GI:148244721"
                     /db_xref="GeneID:5172515"
                     /translation="MYGEEMTLADLERDNNGYLKDLNEWNEDIAVELSKEEGITLTDD
                     SFKLINFLRNEYINNNANQPNERNMVKSLKDDWKGKLSTKELYVLFPKGPAKQAGKIA
                     GLPETKRKGGY"
     misc_feature    600404..600706
                     /gene="yccK"
                     /locus_tag="COSY_0575"
                     /note="DsrC like protein; Region: DsrC; pfam04358"
                     /db_xref="CDD:146805"
     gene            complement(601436..602743)
                     /gene="aroA"
                     /locus_tag="COSY_0576"
                     /db_xref="GeneID:5171842"
     CDS             complement(601436..602743)
                     /gene="aroA"
                     /locus_tag="COSY_0576"
                     /EC_number="2.5.1.19"
                     /note="catalyzes the formation of
                     5-O-(1-carboxyvinyl)-3-phosphoshikimate from
                     phosphoenolpyruvate and 3-phosphoshikimate in tryptophan
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="YP_001219416.1"
                     /db_xref="GI:148244722"
                     /db_xref="GeneID:5171842"
                     /translation="MSKFIINPSNSMYGNLKIPGDKSISHRSIMLGSLANGVTKISGF
                     LEGKDVLSTLKGFQNMGVKIERNSDNVIIYGVGLNGLKKSLVPLNFGNSGTSIRLISG
                     ILAAQTFDSELYGDESLSKRPMGRVINPLVQMGALIESNDGKLPIKIKGGQTLKGINY
                     DLPVASAQVKSCILLAGLYAQGETCIKESILTRDHTERMLKGLGYRLDTNKNKICLTG
                     GAQLNAANIQVPSDISSAAFFIVAASIAPQADITLIGVNVNPTRTGIIDILKLMGANL
                     SLSNECVIGGELLANIRIQSAQLKGIRIPKDLVPLAIDEFPAIFIAASCAKGETILTN
                     AKELRVKESDRIQVMADGLSILGIENEVFEDGIKIKGGVFSKPSSTIKSHHDHRISMS
                     FAIASLRCHYAIEIEDVDNVQTSFPNFVELANQIGMNISLVSA"
     misc_feature    complement(601451..602743)
                     /gene="aroA"
                     /locus_tag="COSY_0576"
                     /note="3-phosphoshikimate 1-carboxyvinyltransferase;
                     Provisional; Region: PRK02427"
                     /db_xref="CDD:235037"
     misc_feature    complement(601466..602710)
                     /gene="aroA"
                     /locus_tag="COSY_0576"
                     /note="EPSP synthase domain. 3-phosphoshikimate
                     1-carboxyvinyltransferase
                     (5-enolpyruvylshikimate-3-phosphate synthase) (EC
                     2.5.1.19) catalyses the reaction between
                     shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP)
                     to form...; Region: EPSP_synthase; cd01556"
                     /db_xref="CDD:238797"
     misc_feature    complement(order(602048..602059,602681..602692))
                     /gene="aroA"
                     /locus_tag="COSY_0576"
                     /note="hinge; other site"
                     /db_xref="CDD:238797"
     misc_feature    complement(order(601502..601504,601580..601585,
                     601709..601711,601718..601723,601733..601735,
                     601802..601804,602168..602170,602177..602179,
                     602240..602248,602378..602380,602459..602464,
                     602468..602470,602663..602665,602675..602680))
                     /gene="aroA"
                     /locus_tag="COSY_0576"
                     /note="active site"
                     /db_xref="CDD:238797"
     gene            complement(602748..603602)
                     /locus_tag="COSY_0577"
                     /db_xref="GeneID:5172174"
     CDS             complement(602748..603602)
                     /locus_tag="COSY_0577"
                     /EC_number="1.3.1.12"
                     /note="Similar to the N-terminal region of bifunctional
                     protein TyrA PFL_4310 (741 aa) in Pseudomonas fluorescens
                     Pf-5, prephenate dehydrogenase / 3-phosphoshikimate
                     1-carboxyvinyltransferase (EC:1.2.1.3 EC:5.4.99.5)."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="YP_001219417.1"
                     /db_xref="GI:148244723"
                     /db_xref="GeneID:5172174"
                     /translation="MIDRICIIGVGLIGGSFVAGLKQTNQVKTVIGFSRQESHLRKAQ
                     EMGIIDEYSLDISQVLKQVQMVIIATPVNSFQAILEMIKPHIDESVIISDVGSTKGSV
                     IQIAKLVFGQMPAKFIPAHPIAGKEKSGIEAVDAQLFNHKRVVLTPTESSDIQTIAIL
                     SGLWKELGAKVEIMTDKKHDDLLAMTSHLPHMLAYGLMDYLISNNPYACRYVAGGFKD
                     FSRIASSDALMWRDICINNPKEIVKHIEGYQKTLEKISNLIKNNKAEALEQLFQEAKS
                     ARDNWFSS"
     misc_feature    complement(602760..603602)
                     /locus_tag="COSY_0577"
                     /note="Prephenate dehydrogenase [Amino acid transport and
                     metabolism]; Region: TyrA; COG0287"
                     /db_xref="CDD:223364"
     misc_feature    complement(602766..603590)
                     /locus_tag="COSY_0577"
                     /note="prephenate dehydrogenase; Validated; Region:
                     PRK08507"
                     /db_xref="CDD:181452"
     gene            complement(603599..603889)
                     /locus_tag="COSY_0578"
                     /db_xref="GeneID:5172572"
     CDS             complement(603599..603889)
                     /locus_tag="COSY_0578"
                     /note="Similar to the N-terminal region of
                     histidinol-phosphate aminotransferase HisH (366 aa) in
                     Haemophilus influenzae Rd KW20."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219418.1"
                     /db_xref="GI:148244724"
                     /db_xref="GeneID:5172572"
                     /translation="MNICSIGKFIKPYQSAKYITILCSELRLKYVTRLISKENSLDII
                     LRVQKVIFEIHSYPYGIDFKLKQSLIKHLNFNTDCITLNSSNDFLEALKSLL"
     misc_feature    complement(<603620..603862)
                     /locus_tag="COSY_0578"
                     /note="histidinol-phosphate aminotransferase; Validated;
                     Region: PRK02731"
                     /db_xref="CDD:235064"
     gene            complement(603992..605092)
                     /gene="pheA"
                     /locus_tag="COSY_0579"
                     /db_xref="GeneID:5172596"
     CDS             complement(603992..605092)
                     /gene="pheA"
                     /locus_tag="COSY_0579"
                     /EC_number="4.2.1.51"
                     /EC_number="5.4.99.5"
                     /note="bifunctional chorismate mutase / prephenate
                     dehydratase in phenylalanine, tyrosine and tryptophan
                     biosynthesis pathway."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein PheA"
                     /protein_id="YP_001219419.1"
                     /db_xref="GI:148244725"
                     /db_xref="GeneID:5172596"
                     /translation="MGKRTLSELRDEIDVLDKKIQLLIGNRAQLVAKVAQVKKASDDS
                     SVFYRPEREAQVLRSIIKRNNSLLKDKDMAYIFRQIMSACLALEQPLNIAYLGPEGTF
                     TQEAALKHFGHSVSTLDCVSIDDIFHQVEKGNAHYGVVPIENSSNGMIGATVDMLYSQ
                     NLKICGEVEIAIQHQLMSANQSQGITVIYAHSQALNQCQRWLNNNYPNTELKSVASNA
                     LAACIVKDEVGAAAIASEVALDLYGLERIAKNIEDKAGNVTRFLILGKENISTSFENI
                     STSFEGKTSLLVVIKHESGTLCDLLEPFKQQGINMIQLEKHPIPGVKWEYLFLIDIEG
                     HKDNKKVKLALTEVASRVLKVNVLGSYPIAVL"
     misc_feature    complement(604850..605077)
                     /gene="pheA"
                     /locus_tag="COSY_0579"
                     /note="Chorismate mutase type II; Region: CM_2; cl00693"
                     /db_xref="CDD:242033"
     misc_feature    complement(603995..604828)
                     /gene="pheA"
                     /locus_tag="COSY_0579"
                     /note="Prephenate dehydratase [Amino acid transport and
                     metabolism]; Region: PheA; COG0077"
                     /db_xref="CDD:223155"
     misc_feature    complement(604286..604816)
                     /gene="pheA"
                     /locus_tag="COSY_0579"
                     /note="Prephenate dehydratase; Region: PDT; pfam00800"
                     /db_xref="CDD:216127"
     misc_feature    complement(604007..604246)
                     /gene="pheA"
                     /locus_tag="COSY_0579"
                     /note="C-terminal ACT domain of the bifunctional
                     chorismate mutase-prephenate dehydratase (CM-PDT) enzyme
                     and the prephenate dehydratase (PDT) enzyme; Region:
                     ACT_CM-PDT; cd04905"
                     /db_xref="CDD:153177"
     misc_feature    complement(order(604139..604150,604199..604210))
                     /gene="pheA"
                     /locus_tag="COSY_0579"
                     /note="putative L-Phe binding site [chemical binding];
                     other site"
                     /db_xref="CDD:153177"
     gene            complement(605103..606260)
                     /gene="serA"
                     /locus_tag="COSY_0580"
                     /db_xref="GeneID:5172616"
     CDS             complement(605103..606260)
                     /gene="serA"
                     /locus_tag="COSY_0580"
                     /EC_number="1.1.1.95"
                     /note="D-isomer specific 2-hydroxyacid dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="YP_001219420.1"
                     /db_xref="GI:148244726"
                     /db_xref="GeneID:5172616"
                     /translation="MIKVLTLNNISSIGLNKLPRDNYKISSKMSNPDVVLVRSAKMYD
                     MEINDNLKVVGRAGAGVNNIPLDKMSNKGVVVFNAPGANANAVKELVISSMLLASRNI
                     CQAWYYVNCLSLDNLKTAIEEGKKKYAGSELPSKTLGIVGLGAIGVKIANAAHALGMN
                     VIGFDPLITIKSAWKLSSGVEQVLSIDELFSRSNFVSFHVPLVENTKNLLNKERIALL
                     PEDATILNFARDGIVNEEALMIALNNGKVKYYVTDFPIDDKKDHDRVIALPHLGASTV
                     EAEDNCAIMVVNQIRDYLENGNITNSVNFPEVLMPRAGKNRLAITHKNIPNMVGQIST
                     TIADTSANIIDMLNKSKNNIAYTLVDLEHEIPVSIVDNLKQVKGILTVRGL"
     misc_feature    complement(605349..606254)
                     /gene="serA"
                     /locus_tag="COSY_0580"
                     /note="Putative D-3-Phosphoglycerate Dehydrogenases,
                     NAD-binding and catalytic domains; Region: PGDH_like_3;
                     cd12174"
                     /db_xref="CDD:240651"
     misc_feature    complement(order(605451..605453,605574..605576,
                     606012..606014,606081..606089,606144..606146))
                     /gene="serA"
                     /locus_tag="COSY_0580"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:240651"
     misc_feature    complement(order(605442..605447,605451..605453,
                     605502..605507,605574..605582,605643..605645,
                     605658..605666,605763..605771,605823..605837,
                     606000..606002,606012..606014,606084..606086))
                     /gene="serA"
                     /locus_tag="COSY_0580"
                     /note="putative NAD binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240651"
     misc_feature    complement(order(605451..605453,605493..605495,
                     605574..605576))
                     /gene="serA"
                     /locus_tag="COSY_0580"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:240651"
     misc_feature    complement(605106..605312)
                     /gene="serA"
                     /locus_tag="COSY_0580"
                     /note="C-terminal ACT (regulatory) domain of
                     D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi
                     and bacteria; Region: ACT_3PGDH; cd04901"
                     /db_xref="CDD:153173"
     misc_feature    complement(order(605235..605237,605289..605291,
                     605295..605297))
                     /gene="serA"
                     /locus_tag="COSY_0580"
                     /note="L-serine binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:153173"
     misc_feature    complement(order(605211..605231,605235..605237,
                     605262..605264,605271..605276,605283..605285,
                     605289..605291))
                     /gene="serA"
                     /locus_tag="COSY_0580"
                     /note="ACT domain interface; other site"
                     /db_xref="CDD:153173"
     gene            complement(606260..607339)
                     /gene="serC"
                     /locus_tag="COSY_0581"
                     /db_xref="GeneID:5171881"
     CDS             complement(606260..607339)
                     /gene="serC"
                     /locus_tag="COSY_0581"
                     /EC_number="2.6.1.52"
                     /note="catalyzes the formation of 3-phosphonooxypyruvate
                     and glutamate from O-phospho-L-serine and 2-oxoglutarate;
                     required both in major phosphorylated pathway of serine
                     biosynthesis and in the biosynthesis of pyridoxine"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine aminotransferase"
                     /protein_id="YP_001219421.1"
                     /db_xref="GI:148244727"
                     /db_xref="GeneID:5171881"
                     /translation="MSQVYNFSAGPAMLPIQVLRQMQDELLEYEDVKASIMEISHRST
                     DFIAMAQKSEQDLRDLMNIPNHYKVLFLQGGASAQFSMVPINLLHGKTKANYAYTGHW
                     SKKAIVEGSRYCDVNICTNSSDNKYTDIDVFENWDIDPDGAYLHYTPNETIAGLEFDY
                     VPEVDMPLVADMSSSILSREVDVSKYGVIYAGAQKNIGIAGLTVVIVREDLMGSVVAN
                     QPILFDYTIQAKNDSMYNTPSTYSWYVASRVFEWLKQQGGLSVIAKINQTKAKTLYDV
                     IDGSNFYSNPVALKYRSWMNVPFLLADENLNGLFVEKAAINNLITLKGHRSVGGMRAS
                     IYNAMPQKGINELINFMKVFEKENS"
     misc_feature    complement(606263..607339)
                     /gene="serC"
                     /locus_tag="COSY_0581"
                     /note="3-phosphoserine/phosphohydroxythreonine
                     aminotransferase; Provisional; Region: PRK05355"
                     /db_xref="CDD:235428"
     misc_feature    complement(order(606755..606757,606764..606766,
                     606818..606820,606827..606829,606896..606898,
                     607100..607102,607109..607114))
                     /gene="serC"
                     /locus_tag="COSY_0581"
                     /note="pyridoxal 5'-phosphate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:99742"
     misc_feature    complement(606755..606757)
                     /gene="serC"
                     /locus_tag="COSY_0581"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99742"
     gene            609059..609628
                     /locus_tag="COSY_0582"
                     /db_xref="GeneID:5171890"
     CDS             609059..609628
                     /locus_tag="COSY_0582"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219422.1"
                     /db_xref="GI:148244728"
                     /db_xref="GeneID:5171890"
                     /translation="MINKIHKTKTIFAIFIMVILIITTRGNINWQSSIIHLPDFTIPA
                     LFIAGVYLRTFWTAIVIIISAIIIDNYTIIHKGVSANCITPAYSILLLTYYGIFWVGK
                     YLTTLKIDHNIIKNALIIIITCITQWFVATASYFAFTTSFWGKFGLYIAHWSIIEIPL
                     ILYWMIAICSIFTLNHRYLIIPFFSTRKD"
     gene            609635..610228
                     /gene="cobO"
                     /locus_tag="COSY_0583"
                     /db_xref="GeneID:5172193"
     CDS             609635..610228
                     /gene="cobO"
                     /locus_tag="COSY_0583"
                     /EC_number="2.5.1.17"
                     /note="ATP:corrinoid adenosyltransferase BtuR/CobO/CobP"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)alamin adenosyltransferase"
                     /protein_id="YP_001219423.1"
                     /db_xref="GI:148244729"
                     /db_xref="GeneID:5172193"
                     /translation="MVENHYKARMQRKKFYINTRIKQANIDKGIIVLLTGNGKGKSSS
                     ALGMVCRALGYNMKIAIAKFLKGVQTTGEDIFLAKQPNVQTTYMKTGFTWDTQDKTFD
                     TDMAQETWGKAEQYLNDDSINLVVLDELTYMINYQYLYEAQIINTLNNRPKKQHVIIT
                     GRVASQKLIKLADTVSEIKDIKHAFRANIKAQKGIEL"
     misc_feature    609650..610222
                     /gene="cobO"
                     /locus_tag="COSY_0583"
                     /note="ATP:corrinoid adenosyltransferase [Coenzyme
                     metabolism]; Region: BtuR; COG2109"
                     /db_xref="CDD:225020"
     misc_feature    609710..610222
                     /gene="cobO"
                     /locus_tag="COSY_0583"
                     /note="ATP:corrinoid adenosyltransferase BtuR/CobO/CobP;
                     Region: CobA_CobO_BtuR; pfam02572"
                     /db_xref="CDD:217113"
     gene            complement(610250..611509)
                     /gene="glyA"
                     /locus_tag="COSY_0584"
                     /db_xref="GeneID:5172131"
     CDS             complement(610250..611509)
                     /gene="glyA"
                     /locus_tag="COSY_0584"
                     /EC_number="2.1.2.1"
                     /note="catalyzes the reaction of glycine with
                     5,10-methylenetetrahydrofolate to form L-serine and
                     tetrahydrofolate"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="YP_001219424.1"
                     /db_xref="GI:148244730"
                     /db_xref="GeneID:5172131"
                     /translation="MFDKSQTLAKVDAEIYKAIVLEETRQETHIELIASENYTSPAVM
                     ETQGSKLTNKYAEGYPCKRYYGGCEYVDMVEQLAIDRAKTLFGADYANVQPHSGSQAN
                     AAVFQALLVPGDTILGMSLAHGGHLTHGATPSFSGKNFNSIQYGLNQKTGEIDYEQVE
                     VLAKRYKPKMIIAGFSAYSRMVDWQRFREIADSVGAYLMVDMAHVAGLIATGEYPSPV
                     AIADVTTTTTHKTLRGPRGGLILAKSNKTIEKKLNAAIFPGIQGGPLMHIIAAKAVSF
                     KEAMSDEYKTYQKQVKINAQVMANTFIKRGFDVVSGGTDNHLFLVSFIDQGLTGKAVD
                     TALGSAYITVNMNAVPNDPNPPFVTSGIRVGTPSVTTRGFNEIDCSDLASWMCDICDD
                     LGNQEVIYKIRGRVVSLCAKYPVYLDD"
     misc_feature    complement(610262..611500)
                     /gene="glyA"
                     /locus_tag="COSY_0584"
                     /note="serine hydroxymethyltransferase; Reviewed; Region:
                     glyA; PRK00011"
                     /db_xref="CDD:234571"
     misc_feature    complement(610283..611485)
                     /gene="glyA"
                     /locus_tag="COSY_0584"
                     /note="Serine-glycine hydroxymethyltransferase (SHMT).
                     This family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). SHMT
                     carries out interconversion of serine and glycine; it
                     catalyzes the transfer of hydroxymethyl...; Region: SHMT;
                     cd00378"
                     /db_xref="CDD:99733"
     misc_feature    complement(order(610661..610663,610715..610717,
                     611093..611098,611201..611203,611222..611224,
                     611267..611269,611291..611296,611348..611350,
                     611402..611404,611417..611419,611444..611449,
                     611468..611470,611474..611476))
                     /gene="glyA"
                     /locus_tag="COSY_0584"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:99733"
     misc_feature    complement(order(610421..610423,610820..610822,
                     611132..611134,611405..611407))
                     /gene="glyA"
                     /locus_tag="COSY_0584"
                     /note="active site"
                     /db_xref="CDD:99733"
     misc_feature    complement(order(610421..610423,610802..610804,
                     610820..610825,610898..610900,610907..610909,
                     610982..610984,611132..611134,611213..611218,
                     611315..611317,611345..611347,611405..611407))
                     /gene="glyA"
                     /locus_tag="COSY_0584"
                     /note="glycine-pyridoxal phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99733"
     misc_feature    complement(order(610469..610471,610739..610741,
                     611129..611131,611135..611137,611147..611149,
                     611318..611320,611339..611341))
                     /gene="glyA"
                     /locus_tag="COSY_0584"
                     /note="folate binding site [chemical binding]; other site"
                     /db_xref="CDD:99733"
     gene            complement(612096..612169)
                     /locus_tag="COSY_t22"
                     /db_xref="GeneID:5329747"
     tRNA            complement(612096..612169)
                     /locus_tag="COSY_t22"
                     /product="tRNA-Pro"
                     /db_xref="GeneID:5329747"
     gene            complement(612160..612906)
                     /gene="moeB"
                     /locus_tag="COSY_0586"
                     /db_xref="GeneID:5172263"
     CDS             complement(612160..612906)
                     /gene="moeB"
                     /locus_tag="COSY_0586"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin biosynthesis protein MoeB"
                     /protein_id="YP_001219425.1"
                     /db_xref="GI:148244731"
                     /db_xref="GeneID:5172263"
                     /translation="MNDQELLRYSRQILLPQISIKGQQSLKDSTLLLIGMGGLGSPSA
                     LYLASAGIGHLIIADSDKVELSNLQRQIIHSTDDIGRTKVNSAKDKILAINPNIKVTT
                     IGKLSQDNLNNWVAKVDVVLDGTDNFDIRFKINKACVMQRTPLVSAAVIRFEGQLSVF
                     QGYNQTKPCYQCLYSIEGNSDENCTRNGILSPVTGIIGSLQALQAIKVLLNLGEQLVG
                     KLMLIDTLNLSFKKIKINKDESCKICSHGV"
     misc_feature    complement(612184..612906)
                     /gene="moeB"
                     /locus_tag="COSY_0586"
                     /note="molybdopterin biosynthesis protein MoeB;
                     Provisional; Region: PRK05690"
                     /db_xref="CDD:180204"
     misc_feature    complement(612202..612885)
                     /gene="moeB"
                     /locus_tag="COSY_0586"
                     /note="ThiF_MoeB_HesA. Family of E1-like enzymes involved
                     in molybdopterin and thiamine biosynthesis family. The
                     common reaction mechanism catalyzed by MoeB and ThiF, like
                     other E1 enzymes, begins with a nucleophilic attack of the
                     C-terminal carboxylate of MoaD...; Region:
                     ThiF_MoeB_HesA_family; cd00757"
                     /db_xref="CDD:238386"
     misc_feature    complement(order(612517..612519,612535..612537,
                     612658..612660,612697..612699,612724..612726,
                     612730..612732,612790..612792,612796..612798,
                     612802..612804))
                     /gene="moeB"
                     /locus_tag="COSY_0586"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238386"
     misc_feature    complement(order(612205..612210,612214..612216,
                     612235..612237,612247..612249,612439..612441,
                     612445..612447,612457..612462,612514..612516,
                     612526..612534,612790..612792))
                     /gene="moeB"
                     /locus_tag="COSY_0586"
                     /note="substrate interface [chemical binding]; other site"
                     /db_xref="CDD:238386"
     gene            complement(612903..613394)
                     /gene="msrA"
                     /locus_tag="COSY_0587"
                     /db_xref="GeneID:5172394"
     CDS             complement(612903..613394)
                     /gene="msrA"
                     /locus_tag="COSY_0587"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide methionine sulfoxide reductase MsrA"
                     /protein_id="YP_001219426.1"
                     /db_xref="GI:148244732"
                     /db_xref="GeneID:5172394"
                     /translation="MQTAYFSGGCFWCVEAIFQRIVGIIKLTSGYCNGNTSNPTYQDI
                     CLGVTGHAEVVKIEFDEFKISFKVLLDIFFEIHNPTTLNQQGNDRGTQYRSAIFYINN
                     KQQLQAINMINLMSDNIVTQVTKLDCFYPAEDYHQNYFNNNLSKPYCQMLIRPKLDKY
                     FSQ"
     misc_feature    complement(612927..613394)
                     /gene="msrA"
                     /locus_tag="COSY_0587"
                     /note="methionine sulfoxide reductase A; Provisional;
                     Region: PRK14054"
                     /db_xref="CDD:237597"
     gene            613810..614277
                     /locus_tag="COSY_0588"
                     /db_xref="GeneID:5172651"
     CDS             613810..614277
                     /locus_tag="COSY_0588"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219427.1"
                     /db_xref="GI:148244733"
                     /db_xref="GeneID:5172651"
                     /translation="MLKRLVEFLKNNHPDANIEEYLDAKYIQLNNLQLKQIANALNNG
                     KLSTKPASNCNANHFIFHFGSTLILLQKDTTNTSKVYQVELSWETDFLSIRSRDKTKG
                     FYFINFEFDNNYNTTLQKTKKTIKGHINNTVKNQEIIDKIMPILKGFMSAITD"
     gene            complement(614346..614675)
                     /gene="himA"
                     /locus_tag="COSY_0589"
                     /db_xref="GeneID:5172105"
     CDS             complement(614346..614675)
                     /gene="himA"
                     /locus_tag="COSY_0589"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor, alpha subunit"
                     /protein_id="YP_001219428.1"
                     /db_xref="GI:148244734"
                     /db_xref="GeneID:5172105"
                     /translation="MSITKKDIANVLVKSMDITHVQALSITHDFFDQIKQTLASGESV
                     KLSSFGNFIIREKSSRVGRNPKTGEMVEISARRVVVFKSGPKLKLATQKDGYFPNYNL
                     KNFVVNL"
     misc_feature    complement(614406..614666)
                     /gene="himA"
                     /locus_tag="COSY_0589"
                     /note="Integration host factor (IHF) and HU are small
                     heterodimeric members of the DNABII protein family that
                     bind and bend DNA, functioning as architectural factors in
                     many cellular processes including transcription,
                     site-specific recombination, and...; Region: HU_IHF;
                     cd00591"
                     /db_xref="CDD:238332"
     misc_feature    complement(order(614406..614408,614427..614429,
                     614433..614435,614445..614450,614514..614516,
                     614529..614534,614541..614555,614565..614570,
                     614577..614582,614589..614591,614631..614633,
                     614643..614645,614652..614654,614661..614666))
                     /gene="himA"
                     /locus_tag="COSY_0589"
                     /note="IHF dimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238332"
     misc_feature    complement(order(614421..614423,614430..614432,
                     614436..614438,614448..614450,614478..614489,
                     614496..614498,614502..614507,614511..614513,
                     614523..614525,614532..614537,614541..614543,
                     614547..614549,614592..614594,614658..614666))
                     /gene="himA"
                     /locus_tag="COSY_0589"
                     /note="IHF - DNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238332"
     gene            complement(614675..617041)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /db_xref="GeneID:5172559"
     CDS             complement(614675..617041)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /EC_number="6.1.1.20"
                     /note="catalyzes a two-step reaction, first charging a
                     phenylalanine molecule by linking its carboxyl group to
                     the alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; forms a tetramer of
                     alpha(2)beta(2); binds two magnesium ions per tetramer;
                     type 2 subfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="YP_001219429.1"
                     /db_xref="GI:148244735"
                     /db_xref="GeneID:5172559"
                     /translation="MNILSNWLREWVNPNVTNRILVEHLTMVGLEVDSITSIMPAFKG
                     VVVVGHVVSYNKHPYADKLNLCQVDVGEEKNLQIICGAKNIRSGLKVVVAMVGSQLLN
                     GLEIKIVNFRGVKSFGIICSESELGMSDLSQGIVELEANTPIGKDIREHLNFDNYIIE
                     LNITPNRGDCFSVLGIAREVSANYNLAFNLPVFEVLAQGDCVISTNVVDTKACPKYLT
                     RSIKNIDNTVKTPKWMADKLVYSGQQLHTPVVDILNFVLLELGQPMHVFDLSKLKGNI
                     EVRMAKCDEHIELLNGTTIKLKEDILVVADSNLVLSIAGVMGNMSSSAQNNSTNILLE
                     SAFFELVSISGNARSYGLHTDSSLRFERGVDFNMTELAMDRATQLIVKICGGQASKIS
                     ACIDKSALPQLKPITINQEKIKKILGLELDAKWIEQKFTNLGFEISQQTNNSWTIIPP
                     SFRFDIRIPADLIEELARLYGYDKLPVQKLSLEANINSTSETDINQYNITQSLVNRGY
                     QEIITYSFISEKYQNLISPDARKIRLSNPISIDMSIMRSSLIPGLLQTVESNQRRKHT
                     DARFFEIGLCFDGIEVDEQSNKLAAIVTGNRFSAQWAANLQSLDFFDIKADLESLLVL
                     TGSEFYFESGQHAALQKGQTAQIILNDEQVGWIGALSPMVQKQLSLPDCYLFEINLAS
                     IKSRNIVKYKAFSSYQQSRRDIALVLDEVVPVAKLIQSIKSMQQQYFINVILFDVYIG
                     DGIKLGKKSVALSLTYQSLEGTLTETQLNTKVDEVLVLMQTQYSAILR"
     misc_feature    complement(614678..617041)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="phenylalanyl-tRNA synthetase subunit beta;
                     Reviewed; Region: pheT; PRK00629"
                     /db_xref="CDD:234804"
     misc_feature    complement(616598..616879)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="tRNA-binding-domain-containing prokaryotic
                     phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS
                     aminoacylate phenylalanine transfer RNAs (tRNAphe).
                     PheRSs belong structurally to class II aminoacyl tRNA
                     synthetases (aaRSs) but, as they aminoacylate...; Region:
                     tRNA_bind_bactPheRS; cd02796"
                     /db_xref="CDD:239196"
     misc_feature    complement(order(616685..616687,616694..616696,
                     616715..616717,616754..616756,616817..616819,
                     616856..616858))
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="putative tRNA-binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:239196"
     misc_feature    complement(615887..616363)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="B3/4 domain; Region: B3_4; pfam03483"
                     /db_xref="CDD:202662"
     misc_feature    complement(615626..615832)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="tRNA synthetase B5 domain; Region: B5; smart00874"
                     /db_xref="CDD:197942"
     misc_feature    complement(614993..615550)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="Phenylalanyl-tRNA synthetase (PheRS) beta chain
                     core domain. PheRS belongs to class II aminoacyl-tRNA
                     synthetases (aaRS) based upon its structure. While class
                     II aaRSs generally aminoacylate the 3&apos;-OH ribose of
                     the appropriate tRNA,  PheRS is an...; Region:
                     PheRS_beta_core; cd00769"
                     /db_xref="CDD:238392"
     misc_feature    complement(order(615191..615193,615287..615289,
                     615305..615307,615311..615313,615317..615319,
                     615332..615334,615362..615364,615404..615406,
                     615437..615448,615500..615508,615512..615514,
                     615518..615520,615530..615532,615539..615541))
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238392"
     misc_feature    complement(615500..615520)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="motif 1; other site"
                     /db_xref="CDD:238392"
     misc_feature    complement(615377..615388)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="motif 3; other site"
                     /db_xref="CDD:238392"
     misc_feature    complement(615305..615313)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="motif 2; other site"
                     /db_xref="CDD:238392"
     misc_feature    complement(614678..614959)
                     /gene="pheT"
                     /locus_tag="COSY_0590"
                     /note="Ferredoxin-fold anticodon binding domain; Region:
                     FDX-ACB; pfam03147"
                     /db_xref="CDD:202554"
     gene            complement(617038..618063)
                     /gene="pheS"
                     /locus_tag="COSY_0591"
                     /db_xref="GeneID:5171833"
     CDS             complement(617038..618063)
                     /gene="pheS"
                     /locus_tag="COSY_0591"
                     /EC_number="6.1.1.20"
                     /note="catalyzes a two-step reaction, first charging a
                     phenylalanine molecule by linking its carboxyl group to
                     the alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; forms a heterotetramer of
                     alpha(2)beta(2); binds two magnesium ions per tetramer;
                     type 1 subfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="YP_001219430.1"
                     /db_xref="GI:148244736"
                     /db_xref="GeneID:5171833"
                     /translation="MVSDLIDTILDRAKTSIEKIKNLQELEDLRVSFLGKKGELTFLL
                     KNLGKLSKEQRPKMGEAINQVKVNIQMLLTDKKNYLEFVVLEKRLLAEKIDVSLPGRH
                     AEMGGLHPITITLNRIQSLFVKNGFEIVMGPEIEDDFHNFTALNIPKHHPARTMHDTF
                     YIDKKTLLRTHTSPVQIRTLEKQNPPVRIITSGRVYRFDSDITHTPMFHQIEGLIVDK
                     YANFAQLKGLLIDLLRTFFEKEVLKVRFRPSYFPFTEPSAEADIECVMCSGKGCRVCK
                     KTGWLEVLGCGVVHPNVLSSVNIDSEVYTGLAFGIGIERLSMLRYSVNDLRLFFENDN
                     RFLRQFR"
     misc_feature    complement(617044..618048)
                     /gene="pheS"
                     /locus_tag="COSY_0591"
                     /note="phenylalanyl-tRNA synthetase subunit alpha;
                     Validated; Region: pheS; PRK00488"
                     /db_xref="CDD:234780"
     misc_feature    complement(617794..618012)
                     /gene="pheS"
                     /locus_tag="COSY_0591"
                     /note="Aminoacyl tRNA synthetase class II, N-terminal
                     domain; Region: Phe_tRNA-synt_N; pfam02912"
                     /db_xref="CDD:111764"
     misc_feature    complement(617059..617739)
                     /gene="pheS"
                     /locus_tag="COSY_0591"
                     /note="Phenylalanyl-tRNA synthetase (PheRS) alpha chain
                     catalytic core domain. PheRS belongs to class II
                     aminoacyl-tRNA synthetases (aaRS) based upon its structure
                     and the presence of three characteristic sequence motifs.
                     This domain is primarily responsible...; Region:
                     PheRS_alpha_core; cd00496"
                     /db_xref="CDD:238277"
     misc_feature    complement(order(617062..617070,617074..617076,
                     617191..617196,617287..617289,617293..617301,
                     617320..617322,617383..617388,617392..617400,
                     617449..617451,617470..617472,617476..617478,
                     617482..617484,617488..617490,617500..617508,
                     617527..617529,617572..617589,617599..617601,
                     617614..617616,617665..617673,617677..617682,
                     617695..617697,617716..617721,617728..617730,
                     617737..617739))
                     /gene="pheS"
                     /locus_tag="COSY_0591"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238277"
     misc_feature    complement(617665..617685)
                     /gene="pheS"
                     /locus_tag="COSY_0591"
                     /note="motif 1; other site"
                     /db_xref="CDD:238277"
     misc_feature    complement(order(617086..617088,617119..617121,
                     617128..617139,617203..617220,617302..617307,
                     617311..617313,617428..617430,617434..617436,
                     617440..617442,617449..617457,617467..617469,
                     617473..617475,617536..617538,617545..617547,
                     617551..617553,617593..617601))
                     /gene="pheS"
                     /locus_tag="COSY_0591"
                     /note="active site"
                     /db_xref="CDD:238277"
     misc_feature    complement(617467..617478)
                     /gene="pheS"
                     /locus_tag="COSY_0591"
                     /note="motif 2; other site"
                     /db_xref="CDD:238277"
     misc_feature    complement(617119..617136)
                     /gene="pheS"
                     /locus_tag="COSY_0591"
                     /note="motif 3; other site"
                     /db_xref="CDD:238277"
     gene            complement(618423..618782)
                     /gene="rplT"
                     /locus_tag="COSY_0592"
                     /db_xref="GeneID:5171836"
     CDS             complement(618423..618782)
                     /gene="rplT"
                     /locus_tag="COSY_0592"
                     /note="binds directly to 23S ribosomal RNA prior to in
                     vitro assembly of the 50S ribosomal subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="YP_001219431.1"
                     /db_xref="GI:148244737"
                     /db_xref="GeneID:5171836"
                     /translation="MARVSRGVQAHAKHKKILKKAKGYYGARSKVYRIAKQAIIKAGQ
                     YAYRDRRQRRRQFRRLWIVRINAEARNNGLSYSRMINGMSKAGIEIDRKVLSDIAIFD
                     KVAFAKIVDQVKQALSV"
     misc_feature    complement(618450..>618701)
                     /gene="rplT"
                     /locus_tag="COSY_0592"
                     /note="Ribosomal protein L20; Region: Ribosomal_L20;
                     cd07026"
                     /db_xref="CDD:197305"
     misc_feature    complement(order(618501..618509,618531..618533,
                     618540..618545,618552..618557,618573..618575,
                     618585..618587,618594..618602,618606..618650,
                     618657..618662,618672..618677,618684..618695,
                     618699..618701))
                     /gene="rplT"
                     /locus_tag="COSY_0592"
                     /note="23S rRNA binding site [nucleotide binding]; other
                     site"
                     /db_xref="CDD:197305"
     misc_feature    complement(order(618456..618461,618477..618482,
                     618498..618500,618507..618518,618633..618635,
                     618642..618647,618651..618656,618663..618665,
                     618675..618677))
                     /gene="rplT"
                     /locus_tag="COSY_0592"
                     /note="L21 binding site [polypeptide binding]; other site"
                     /db_xref="CDD:197305"
     misc_feature    complement(order(618483..618485,618492..618494,
                     618501..618503,618573..618575,618579..618584,
                     618591..618593,618600..618605,618612..618614))
                     /gene="rplT"
                     /locus_tag="COSY_0592"
                     /note="L13 binding site [polypeptide binding]; other site"
                     /db_xref="CDD:197305"
     gene            complement(618795..618992)
                     /gene="rpmI"
                     /locus_tag="COSY_0593"
                     /db_xref="GeneID:5172368"
     CDS             complement(618795..618992)
                     /gene="rpmI"
                     /locus_tag="COSY_0593"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="YP_001219432.1"
                     /db_xref="GI:148244738"
                     /db_xref="GeneID:5172368"
                     /translation="MPKLKTNKGAAKRFKKTASGGYKCKHSHLRHILTKKSTSRKRSL
                     RAPDSIEKVDIPMVRKMLPYS"
     misc_feature    complement(618798..618992)
                     /gene="rpmI"
                     /locus_tag="COSY_0593"
                     /note="50S ribosomal protein L35; Reviewed; Region: rpmI;
                     PRK00172"
                     /db_xref="CDD:234676"
     gene            complement(619047..619496)
                     /gene="infC"
                     /locus_tag="COSY_0594"
                     /db_xref="GeneID:5172563"
     CDS             complement(619047..619496)
                     /gene="infC"
                     /locus_tag="COSY_0594"
                     /note="Similar to the C-terminal region of translation
                     initiation factor IF-3 (178 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="YP_001219433.1"
                     /db_xref="GI:148244739"
                     /db_xref="GeneID:5172563"
                     /translation="MQIGIVNTDIAKQEAIQSELDLVEVSPSAQPPVCKIMDFGKFLY
                     GLKQQKKEAKKKQKRNTVKTIKYRPGTEESDYQIKFRNLVKFLDNGDKVKVGIWFRGR
                     EMQHKELGMKMLDRIEKDTEDFANVEQKAKMEGRQLGMMLAPKSKKK"
     misc_feature    complement(619053..619493)
                     /gene="infC"
                     /locus_tag="COSY_0594"
                     /note="translation initiation factor IF-3; Reviewed;
                     Region: infC; PRK00028"
                     /db_xref="CDD:234582"
     misc_feature    complement(619365..>619493)
                     /gene="infC"
                     /locus_tag="COSY_0594"
                     /note="Translation initiation factor IF-3, N-terminal
                     domain; Region: IF3_N; pfam05198"
                     /db_xref="CDD:191228"
     misc_feature    complement(619062..619316)
                     /gene="infC"
                     /locus_tag="COSY_0594"
                     /note="Translation initiation factor IF-3, C-terminal
                     domain; Region: IF3_C; pfam00707"
                     /db_xref="CDD:201407"
     gene            complement(619556..621466)
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /db_xref="GeneID:5172619"
     CDS             complement(619556..621466)
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /EC_number="6.1.1.3"
                     /note="catalyzes a two-step reaction, first charging a
                     threonine molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; catalyzes the formation
                     of threonyl-tRNA(Thr) from threonine and tRNA(Thr)"
                     /codon_start=1
                     /transl_table=11
                     /product="threonyl-tRNA synthetase"
                     /protein_id="YP_001219434.1"
                     /db_xref="GI:148244740"
                     /db_xref="GeneID:5172619"
                     /translation="MPIITLPDGTKKIFEQVVSVEQVAKSMGLVKAALAGEVDGELVS
                     TSFLIKTDANLTIITANDDQGLEIIRHSTAHLLAQATQMLYPDAQVTIGPVIDNGFYY
                     DFAYKNGFLEGDLIKIEKNMHKLVKQNLKIEKFEMSRDETLQFFKDKGEYYKVKIIES
                     ISTDQILSLYKQGDFIDLCRGPHVPSTAKLKNFKLMKLAGAYWRGDSSNEMLQRVYGT
                     AWGNEQDLKVYLHKLEEVARRDHRKIGKTQDLFHIQEETPGMVFWHAKGWILYQLVEQ
                     YMRGIFRDNGYQEVHTPQLIDKSLWEKSGHWDKFGDVMFTTTSGDRDYAVKPMNCPAH
                     IQIYNQGLKSYRNLPLRLAEFGSCHRNEPSGTLHGIMRVRNFVQDDGHIFCTPEQIQD
                     EVSTFIDLTFNVYKYFGFEKINIKLSTRPKKRVGSDEVWDKSEIALVEALNAKNIVWE
                     LQEGEGAFYGPKIEFILKDCLDRQWQCGTLQVDFSMPKRLGAQFIDENSVKKTPVILH
                     RAIMGSLERFLGILIEHYEGAYPCWLSPIQAVIINISEKHAKFIVDIVKKLKKQGLRV
                     ISDLRNEKVSFKIREHSLQRYPYILVVGDREMEKGQVSVRQRGGKDLGAMSVGTFIKK
                     VNQETLLKNQIK"
     misc_feature    complement(619583..621466)
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="threonyl-tRNA synthetase; Reviewed; Region: thrS;
                     PRK00413"
                     /db_xref="CDD:234752"
     misc_feature    complement(621287..621457)
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is
                     a class II tRNA synthetase that couples threonine to its
                     cognate tRNA.  In addition to its catalytic and
                     anticodon-binding domains, ThrRS has an N-terminal TGS
                     domain, named after the ThrRS, GTPase, and...; Region:
                     TGS_ThrRS_N; cd01667"
                     /db_xref="CDD:133437"
     misc_feature    complement(620822..620968)
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="Threonyl and Alanyl tRNA synthetase second
                     additional domain; Region: tRNA_SAD; smart00863"
                     /db_xref="CDD:197931"
     misc_feature    complement(619859..620752)
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="Threonyl-tRNA synthetase (ThrRS) class II core
                     catalytic domain. ThrRS is a homodimer. It is responsible
                     for the attachment of threonine to the 3&apos; OH group of
                     ribose of the appropriate tRNA. This domain is primarily
                     responsible for ATP-dependent...; Region: ThrRS_core;
                     cd00771"
                     /db_xref="CDD:238394"
     misc_feature    complement(order(619916..619918,619925..619930,
                     620024..620026,620036..620041,620048..620050,
                     620333..620335,620339..620341,620348..620356,
                     620369..620377,620381..620383,620387..620389,
                     620483..620485,620525..620530,620537..620539,
                     620549..620551,620702..620704,620741..620743))
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="active site"
                     /db_xref="CDD:238394"
     misc_feature    complement(order(619976..619978,619982..619984,
                     620129..620137,620261..620263,620342..620347,
                     620375..620377,620384..620386,620390..620392,
                     620429..620437,620441..620449,620456..620461,
                     620495..620497,620501..620512,620516..620524,
                     620576..620578,620582..620590,620594..620596,
                     620600..620605,620615..620620,620663..620665,
                     620672..620674,620678..620683,620687..620689,
                     620693..620695,620699..620707,620711..620713,
                     620729..620731))
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238394"
     misc_feature    complement(620582..620605)
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="motif 1; other site"
                     /db_xref="CDD:238394"
     misc_feature    complement(620381..620392)
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="motif 2; other site"
                     /db_xref="CDD:238394"
     misc_feature    complement(619916..619930)
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="motif 3; other site"
                     /db_xref="CDD:238394"
     misc_feature    complement(619592..619861)
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="ThrRS Threonyl-anticodon binding domain. ThrRS
                     belongs to class II aminoacyl-tRNA synthetases (aaRS).
                     This alignment contains the anticodon binding domain,
                     which is responsible for specificity in tRNA-binding, so
                     that the activated amino acid is...; Region:
                     ThrRS_anticodon; cd00860"
                     /db_xref="CDD:238437"
     misc_feature    complement(order(619649..619651,619655..619657,
                     619685..619687,619709..619711,619727..619729,
                     619832..619837))
                     /gene="thrS"
                     /locus_tag="COSY_0595"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:238437"
     gene            complement(621521..623239)
                     /gene="recJ"
                     /locus_tag="COSY_0596"
                     /db_xref="GeneID:5172040"
     CDS             complement(621521..623239)
                     /gene="recJ"
                     /locus_tag="COSY_0596"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="YP_001219435.1"
                     /db_xref="GI:148244741"
                     /db_xref="GeneID:5172040"
                     /translation="MLIRTIDQNLFDSYSDDIPIFLKKIYAARGINESHLSLNLSRLL
                     KPNFLQLDIALVLLEQALLNQKRILIVGDFDCDGATASVVAVKSLRMMGAKYVDFLVP
                     NRFEHGYGLSEEIVSLAIQEKQPDLIITVDNGISSFDGIKLAKLSGIMVIVTDHHLPN
                     ENLPNADAIINPNLKDCEFLSKNLAGVGVCFYLFSALKTYLSESDYFIHQKIVPPDLR
                     NVLDLVALGTVADVVKFDQNNRILVDQGIKRIQQQKCSPGILALLEISSRPSSTLCAS
                     DLAFSIAPRLNAAGRLSDIACGIRCLLTDDINDARRYAQELERFNQQRKQEQARMQDQ
                     AQAIVDMQELSFTQKDMGHDRFAISLFEPSWHEGIVGIVAGKLKESYHCPVAIFAQSG
                     NYLKGSIRSIPSVHVKDLLDLVDRQNPDLIVKFGGHAMAAGLSIKSENFSNFKQVFSD
                     AIQIHLDNQISKVNLLTDGELEVFELSLNNAQLLVDVGPWGQGFDEPIFYGKFEIIEQ
                     KVVGKKHLKCRLKFKGNTKVFDGIAFFQPLLEFVQVLAVYKLSINSWRGSTSLQLIIV
                     QIKALK"
     misc_feature    complement(621527..623194)
                     /gene="recJ"
                     /locus_tag="COSY_0596"
                     /note="ssDNA exonuclease RecJ; Provisional; Region:
                     PRK11070"
                     /db_xref="CDD:182944"
     misc_feature    complement(622553..623059)
                     /gene="recJ"
                     /locus_tag="COSY_0596"
                     /note="DHH family; Region: DHH; pfam01368"
                     /db_xref="CDD:216459"
     misc_feature    complement(621890..622090)
                     /gene="recJ"
                     /locus_tag="COSY_0596"
                     /note="DHHA1 domain; Region: DHHA1; pfam02272"
                     /db_xref="CDD:216955"
     gene            complement(623229..623780)
                     /locus_tag="COSY_0597"
                     /db_xref="GeneID:5172459"
     CDS             complement(623229..623780)
                     /locus_tag="COSY_0597"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219436.1"
                     /db_xref="GI:148244742"
                     /db_xref="GeneID:5172459"
                     /translation="MHKIIVFLVLFIYALIINAQLIKVSERENILKSEVKDHRCVLDQ
                     QSKLVWEVKLNDKGLQDANSSYTWFDGQSGVSNGDYSHHCHWGKNCNTQAYINALNIV
                     KLCKQNTWRLPSESELRTLLLYGDNDLLINLLFFPNTKRKSYWSADEQDTNIAIDVPF
                     FYGGSKSSDKSFDAYIRAVSNAY"
     misc_feature    complement(623415..623660)
                     /locus_tag="COSY_0597"
                     /note="Protein of unknown function (DUF1566); Region:
                     DUF1566; pfam07603"
                     /db_xref="CDD:219484"
     gene            complement(623773..624768)
                     /locus_tag="COSY_0598"
                     /db_xref="GeneID:5172463"
     CDS             complement(623773..624768)
                     /locus_tag="COSY_0598"
                     /note="Similar to glycine oxidase ThiO"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD dependent oxidoreductase"
                     /protein_id="YP_001219437.1"
                     /db_xref="GI:148244743"
                     /db_xref="GeneID:5172463"
                     /translation="MGKMTDCLVIGGGIIGMMSARTLIMEGVSVTLLDQRECGKESSW
                     AGGGIISPLYPWRYDDLTNELSFASQIIYEDLCLQIFEDTGIDPQYIQSGLLMMDEYD
                     LPLAIEWMNRYHVDYQFHVDGALFSNIAQVRNPRLLQALKVDILNKGVDIIEYVKVNN
                     LLIKNNKVIGVRTKDKNYFAQDVIVCSGAWSSKWLKLVDEVFPMKGQMIILKSTKSMV
                     KNIVLDQGRYIIPREDGRVLVGSTMENVGFDNHTDIGVQKSLHKFAYQRFPSLFNVKI
                     EHHWSGFRPASLSGKVILGRHEQFEHLFINTGHFCNGLNMAPASSDRIKQLIINA"
     misc_feature    complement(<624634..624759)
                     /locus_tag="COSY_0598"
                     /note="hydroxyglutarate oxidase; Provisional; Region:
                     PRK11728"
                     /db_xref="CDD:183292"
     misc_feature    complement(623785..624702)
                     /locus_tag="COSY_0598"
                     /note="glycine oxidase ThiO; Region: thiamin_ThiO;
                     TIGR02352"
                     /db_xref="CDD:233831"
     gene            complement(624756..625214)
                     /gene="lspA"
                     /locus_tag="COSY_0599"
                     /db_xref="GeneID:5172641"
     CDS             complement(624756..625214)
                     /gene="lspA"
                     /locus_tag="COSY_0599"
                     /EC_number="3.4.23.36"
                     /note="lipoprotein signal peptidase; integral membrane
                     protein that removes signal peptides from prolipoproteins
                     during lipoprotein biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein signal peptidase"
                     /protein_id="YP_001219438.1"
                     /db_xref="GI:148244744"
                     /db_xref="GeneID:5172641"
                     /translation="MKVRHYFLLVVLLVVCDQLTKLLAYEYLGIDNSIIINEFLSLTF
                     SHNYGAAFSFLADNSGWQRYFLSGISAISSVIISIWILRTPLRYKFKLISLVLILSGA
                     IGNMIDRITNGFVVDFIDFHYSGFNYPIFNFADIFISVGVVVLIIVDWGK"
     misc_feature    complement(624774..625214)
                     /gene="lspA"
                     /locus_tag="COSY_0599"
                     /note="lipoprotein signal peptidase; Reviewed; Region:
                     lspA; PRK00376"
                     /db_xref="CDD:234739"
     gene            625575..626357
                     /gene="fabI"
                     /locus_tag="COSY_0600"
                     /db_xref="GeneID:5172649"
     CDS             625575..626357
                     /gene="fabI"
                     /locus_tag="COSY_0600"
                     /EC_number="1.3.1.9"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier protein] reductase (NADH)"
                     /protein_id="YP_001219439.1"
                     /db_xref="GI:148244745"
                     /db_xref="GeneID:5172649"
                     /translation="MGFLTGKKALIVGVASNRSIAWGIAQAMAKQDCEIALTYQNDKL
                     KKRVNKCAVICHSNIVIKCNVASDKDIKKTFKELKNYWDNFDIIIHSVAFAPREALNG
                     NYIQATTRENFATTHDISSYSFTALAKYASSMLNDNGALLTVSYLGSIRSIPNYNVMG
                     VAKASLEANVRYMATALGPERGIRVNAVSSGPIKTLAASGIKNFGKLLDYSADSSALK
                     RNVTIEDVGNAAAFLCSDLASGITGEITYVDSGYNFYDKGPN"
     misc_feature    625575..626333
                     /gene="fabI"
                     /locus_tag="COSY_0600"
                     /note="Enoyl-[acyl-carrier-protein]; Region: FabI;
                     COG0623"
                     /db_xref="CDD:223696"
     misc_feature    625590..626333
                     /gene="fabI"
                     /locus_tag="COSY_0600"
                     /note="Enoyl acyl carrier protein (ACP) reductase (ENR),
                     divergent SDR; Region: ENR_SDR; cd05372"
                     /db_xref="CDD:187630"
     misc_feature    order(625611..625619,625629..625634,625692..625694,
                     625761..625769,625845..625856,625929..625931,
                     626004..626012,626040..626042,626061..626063,
                     626142..626153,626157..626168)
                     /gene="fabI"
                     /locus_tag="COSY_0600"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187630"
     misc_feature    order(625662..625664,625767..625778,625785..625787,
                     625881..625892,625896..625904,625911..625916,
                     625923..625928,625935..625940,625947..625949,
                     625959..625961,625968..625970,626016..626021,
                     626025..626036,626040..626045,626052..626057,
                     626064..626069,626076..626081,626085..626102,
                     626106..626111,626193..626195,626202..626204,
                     626220..626231,626247..626249,626256..626261,
                     626268..626270,626283..626285,626289..626327,
                     626331..626333)
                     /gene="fabI"
                     /locus_tag="COSY_0600"
                     /note="homotetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187630"
     misc_feature    order(625767..625778,625881..625892,625896..625904,
                     625911..625916,625923..625928,625935..625940,
                     625947..625949,625956..625961,625968..625970,
                     626016..626021,626025..626033,626040..626045,
                     626052..626057,626064..626069,626076..626081,
                     626085..626093,626097..626105)
                     /gene="fabI"
                     /locus_tag="COSY_0600"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187630"
     misc_feature    order(625851..625853,625857..625859,626010..626012,
                     626040..626042,626049..626051,626061..626063,
                     626163..626168,626175..626177,626184..626186)
                     /gene="fabI"
                     /locus_tag="COSY_0600"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187630"
     misc_feature    order(625932..625934,626010..626012,626049..626051,
                     626061..626063)
                     /gene="fabI"
                     /locus_tag="COSY_0600"
                     /note="active site"
                     /db_xref="CDD:187630"
     gene            complement(626742..628589)
                     /locus_tag="COSY_0601"
                     /db_xref="GeneID:5172508"
     CDS             complement(626742..628589)
                     /locus_tag="COSY_0601"
                     /EC_number="5.2.1.8"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase D"
                     /protein_id="YP_001219440.1"
                     /db_xref="GI:148244746"
                     /db_xref="GeneID:5172508"
                     /translation="MLVSIRNKTKGWISYLIIGLIIIPFALFGISEYFTGASNIKVAS
                     FDGVDISKEEFLSEFNPQKRWLQKELDKKYDKKFDFILKQSILNQMLNKHLLEQLSRK
                     LSYETTTSELNNIIRANDLFKEEGRFSLEKYKKLLRLNGYTTEKYETIKLQELRRTQI
                     KSNLLDSAFITPSQLLRLQKLNDQKRKFSYIIIQTDNHIKEVKVDAQSVKDFYDNKKS
                     LFFAPEQVKIEFIELSLNEIAKKIKVSDNELFNFYENEQENFTTEEERQAQHILLTDE
                     LTAQKVVTLLDNGGDFVKLAKQYSQDSGSKDDAGNLGFFTRGIMVPEFEKKVFAMKSG
                     EVSDLVKSKFGYHIIKLNNIKVKTLKSFDIAKQEILDLYIQKQAQKVFYNLTEQLASL
                     AYETSLEKIVDQMDLKLQVSDFFDKRNTQLNQKIVTTAFSDMVLNKGENSEVLELSKD
                     KLMVIRVREKLVKRQKSFSEVKSEINTHLMTLLAKTFVDNLAKNIVDLLVHNDKDTLE
                     KIMIKNKLKWHRVGWIKRDSNKVKTTIVNKVFALAKPINSKSSYSAQNLERGNAIVID
                     LLGVKTTDIKIVNAVLEKSLLSFESNEVFSNILEMLKSQAEIKIFSRNL"
     misc_feature    complement(626754..628499)
                     /locus_tag="COSY_0601"
                     /note="periplasmic folding chaperone; Provisional; Region:
                     PRK10788"
                     /db_xref="CDD:182731"
     misc_feature    complement(628122..628499)
                     /locus_tag="COSY_0601"
                     /note="SurA N-terminal domain; Region: SurA_N_3; cl07813"
                     /db_xref="CDD:244798"
     misc_feature    complement(627531..627782)
                     /locus_tag="COSY_0601"
                     /note="PPIC-type PPIASE domain; Region: Rotamase;
                     pfam00639"
                     /db_xref="CDD:216038"
     gene            complement(628751..628827)
                     /locus_tag="COSY_t23"
                     /db_xref="GeneID:5329742"
     tRNA            complement(628751..628827)
                     /locus_tag="COSY_t23"
                     /product="tRNA-Asp"
                     /db_xref="GeneID:5329742"
     gene            complement(628839..628914)
                     /locus_tag="COSY_t24"
                     /db_xref="GeneID:5329735"
     tRNA            complement(628839..628914)
                     /locus_tag="COSY_t24"
                     /product="tRNA-Val"
                     /db_xref="GeneID:5329735"
     gene            complement(628963..629238)
                     /gene="hupB"
                     /locus_tag="COSY_0604"
                     /db_xref="GeneID:5172650"
     CDS             complement(628963..629238)
                     /gene="hupB"
                     /locus_tag="COSY_0604"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="YP_001219441.1"
                     /db_xref="GI:148244747"
                     /db_xref="GeneID:5172650"
                     /translation="MNKSDLVAVISQISNLTKADSARALDAMTGAITSALTSGDNVAI
                     TGFGSFVVRDRAARTGRNPQTGEAIQIKASKVPAFKAGKLLKESVNS"
     misc_feature    complement(628975..629235)
                     /gene="hupB"
                     /locus_tag="COSY_0604"
                     /note="Integration host factor (IHF) and HU are small
                     heterodimeric members of the DNABII protein family that
                     bind and bend DNA, functioning as architectural factors in
                     many cellular processes including transcription,
                     site-specific recombination, and...; Region: HU_IHF;
                     cd00591"
                     /db_xref="CDD:238332"
     misc_feature    complement(order(628975..628977,628996..628998,
                     629002..629004,629014..629019,629083..629085,
                     629098..629103,629110..629124,629134..629139,
                     629146..629151,629158..629160,629200..629202,
                     629212..629214,629221..629223,629230..629235))
                     /gene="hupB"
                     /locus_tag="COSY_0604"
                     /note="IHF dimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238332"
     misc_feature    complement(order(628990..628992,628999..629001,
                     629005..629007,629017..629019,629047..629058,
                     629065..629067,629071..629076,629080..629082,
                     629092..629094,629101..629106,629110..629112,
                     629116..629118,629161..629163,629227..629235))
                     /gene="hupB"
                     /locus_tag="COSY_0604"
                     /note="IHF - DNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238332"
     gene            complement(629366..629896)
                     /gene="dsbE"
                     /locus_tag="COSY_0605"
                     /db_xref="GeneID:5172537"
     CDS             complement(629366..629896)
                     /gene="dsbE"
                     /locus_tag="COSY_0605"
                     /note="cytochrome c biogenesis protein CcmG,
                     thiol:disulfide interchange protein DsbE"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="YP_001219442.1"
                     /db_xref="GI:148244748"
                     /db_xref="GeneID:5172537"
                     /translation="MKKFLPLILFFVLASFLYIGLGLDPTKLPSPLLGRAFPNLQVED
                     FNSAKIYAIQDKLQGKISLVNVWASWCVTCRVEHEILMKIAKTNSLQILGINYKDTRK
                     DGNIFLTRLGNPYDSIVFDQLGKLGLELGVYATPETFITDQQGIIRFKRIGELTPRIW
                     ESKISPLIDELRNSMR"
     misc_feature    complement(629390..629884)
                     /gene="dsbE"
                     /locus_tag="COSY_0605"
                     /note="periplasmic protein thiol:disulfide
                     oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385"
                     /db_xref="CDD:129481"
     misc_feature    complement(629414..629794)
                     /gene="dsbE"
                     /locus_tag="COSY_0605"
                     /note="TlpA-like family, DsbE (also known as CcmG and
                     CycY) subfamily; DsbE is a membrane-anchored, periplasmic
                     TRX-like reductase containing a CXXC motif that
                     specifically donates reducing equivalents to apocytochrome
                     c via CcmH, another cytochrome c...; Region:
                     TlpA_like_DsbE; cd03010"
                     /db_xref="CDD:239308"
     misc_feature    complement(order(629675..629677,629684..629686))
                     /gene="dsbE"
                     /locus_tag="COSY_0605"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239308"
     misc_feature    complement(629534..629602)
                     /gene="dsbE"
                     /locus_tag="COSY_0605"
                     /note="central insert; other site"
                     /db_xref="CDD:239308"
     gene            complement(629893..630315)
                     /gene="ccmE"
                     /locus_tag="COSY_0606"
                     /db_xref="GeneID:5172304"
     CDS             complement(629893..630315)
                     /gene="ccmE"
                     /locus_tag="COSY_0606"
                     /note="CycJ; periplasmic heme chaperone that binds heme
                     transiently via a histidine residue and delivers it to
                     newly synthesized and exported c-type cytochromes;
                     requires the ATP hydrolysis activity of the CcmA protein
                     in order to transfer the heme to the apocytochrome; part
                     of the cytochrome c maturation system; periplasmic protein
                     anchored to the inner membrane"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis protein CcmE"
                     /protein_id="YP_001219443.1"
                     /db_xref="GI:148244749"
                     /db_xref="GeneID:5172304"
                     /translation="MTKRQNRMVLVALLVIGVSLAGYLGLKAFNENLLYFLSPTDVTK
                     GRAPKDKDFRLGGMIVKDSIKHDGIKVVFDVTDYSNTFRVNYSGILPDLFKEGQGVIT
                     TGSLVDGVFMATEVLAKHDENYMPPEVADALEKAKNKQ"
     misc_feature    complement(629896..630315)
                     /gene="ccmE"
                     /locus_tag="COSY_0606"
                     /note="cytochrome c-type biogenesis protein CcmE;
                     Reviewed; Region: PRK13254"
                     /db_xref="CDD:237317"
     gene            complement(630487..631227)
                     /gene="ccmC"
                     /locus_tag="COSY_0607"
                     /db_xref="GeneID:5172007"
     CDS             complement(630487..631227)
                     /gene="ccmC"
                     /locus_tag="COSY_0607"
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter membrane protein CcmC"
                     /protein_id="YP_001219444.1"
                     /db_xref="GI:148244750"
                     /db_xref="GeneID:5172007"
                     /translation="MWKWIQTFASPKNFYQISQKIILWLLIPFIILMLIGLYWGLIVA
                     PIDYQQGESYRIMFIHVPAAWMSMFVYLVLAISGGIGLIWKIKLAYVIAKVSAPIGVA
                     FTFLALTTGAVWGKPMWGTWWVWDARLTSELILLFLYLAYMSLNNAFDNPKTASKASS
                     VLAIMGLVNLPIIHYSVKWWNTLHQSASVSVNKVAIQDVDMLIALLLMGMAFKFLYGA
                     LMLMRARDEVLVIEQNSSWVKRIIMEHR"
     misc_feature    complement(630544..631095)
                     /gene="ccmC"
                     /locus_tag="COSY_0607"
                     /note="heme exporter protein CcmC; Region: ccmC;
                     TIGR01191"
                     /db_xref="CDD:233306"
     gene            complement(631266..631925)
                     /locus_tag="COSY_0608"
                     /db_xref="GeneID:5171975"
     CDS             complement(631266..631925)
                     /locus_tag="COSY_0608"
                     /note="peptidase M22"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoprotease"
                     /protein_id="YP_001219445.1"
                     /db_xref="GI:148244751"
                     /db_xref="GeneID:5171975"
                     /translation="MINLLAIDTCTNTCSVSLYTQGETFSRFVQSEKKSSGLILSLCD
                     EIFKASQMSPSALDGIIYTKGPGSFTGVRMCVSVVQGISLAYNIPTLGFSTLELLGFG
                     AFKKYNTSKVAIALDARMSEVYWGIYQNQILCKESLQKPDEVDILGKYFIGVGNGWGV
                     YDNELIQQTGINTCFANFYPKAENLIVLYLTCVNQHIKFSNKLALPTYLRNNVAHKSL
                     K"
     misc_feature    complement(631296..631916)
                     /locus_tag="COSY_0608"
                     /note="tRNA threonylcarbamoyl adenosine modification
                     protein YeaZ; Region: T6A_YeaZ; TIGR03725"
                     /db_xref="CDD:234332"
     misc_feature    complement(<631548..631811)
                     /locus_tag="COSY_0608"
                     /note="Glycoprotease family; Region: Peptidase_M22;
                     pfam00814"
                     /db_xref="CDD:216132"
     gene            632487..632828
                     /gene="rpsF"
                     /locus_tag="COSY_0609"
                     /db_xref="GeneID:5172533"
     CDS             632487..632828
                     /gene="rpsF"
                     /locus_tag="COSY_0609"
                     /note="binds cooperatively with S18 to the S15-16S
                     complex, allowing platform assembly to continue with S11
                     and S21"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="YP_001219446.1"
                     /db_xref="GI:148244752"
                     /db_xref="GeneID:5172533"
                     /translation="MRHYEITLIVHPDQSAQVGTMMDKYKEIINADGGKIHKEEDWGR
                     KHLAYPIKKIYKAHYLMMNIECDQEMLDKLNYNFRFNDAILRSLIISKNKAITTPSIM
                     MVNKDKEKGKS"
     misc_feature    632487..632807
                     /gene="rpsF"
                     /locus_tag="COSY_0609"
                     /note="30S ribosomal protein S6; Reviewed; Region: rpsF;
                     PRK00453"
                     /db_xref="CDD:179034"
     gene            632828..633082
                     /gene="rpsR"
                     /locus_tag="COSY_0610"
                     /db_xref="GeneID:5172286"
     CDS             632828..633082
                     /gene="rpsR"
                     /locus_tag="COSY_0610"
                     /note="binds as a heterodimer with protein S6 to the
                     central domain of the 16S rRNA; helps stabilize the
                     platform of the 30S subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="YP_001219447.1"
                     /db_xref="GI:148244753"
                     /db_xref="GeneID:5172286"
                     /translation="MAKQIKRKRRPQIKINTFCRFTAAGVTKIDYKDIDILLKNIDES
                     GKITPSRMTGTSAKFQRKLTTAIKRARFLALIPYTDKHKK"
     misc_feature    632879..633070
                     /gene="rpsR"
                     /locus_tag="COSY_0610"
                     /note="30S ribosomal protein S18; Reviewed; Region: rpsR;
                     PRK00391"
                     /db_xref="CDD:178997"
     gene            633092..633544
                     /gene="rplI"
                     /locus_tag="COSY_0611"
                     /db_xref="GeneID:5172647"
     CDS             633092..633544
                     /gene="rplI"
                     /locus_tag="COSY_0611"
                     /note="in Escherichia coli this protein is wrapped around
                     the base of the L1 stalk"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="YP_001219448.1"
                     /db_xref="GI:148244754"
                     /db_xref="GeneID:5172647"
                     /translation="MQVILLENIQKLGNLGDIINVKAGYTRNFLIPKGKAKLATKTNL
                     VEFELIRAKLQIAEAKTLKNAKAIETKMTNTICIIQANASEEGKLFGSINTTDIQTSL
                     IKSGFKIEKRNIDIPETIRHTGEYKININLHTNITVSVKIVIEALQKV"
     misc_feature    633092..633529
                     /gene="rplI"
                     /locus_tag="COSY_0611"
                     /note="50S ribosomal protein L9; Reviewed; Region: rplI;
                     PRK00137"
                     /db_xref="CDD:234659"
     misc_feature    633092..633235
                     /gene="rplI"
                     /locus_tag="COSY_0611"
                     /note="Ribosomal protein L9, N-terminal domain; Region:
                     Ribosomal_L9_N; pfam01281"
                     /db_xref="CDD:201708"
     misc_feature    633275..633529
                     /gene="rplI"
                     /locus_tag="COSY_0611"
                     /note="Ribosomal protein L9, C-terminal domain; Region:
                     Ribosomal_L9_C; pfam03948"
                     /db_xref="CDD:146531"
     gene            633630..635075
                     /gene="dnaB"
                     /locus_tag="COSY_0612"
                     /db_xref="GeneID:5172684"
     CDS             633630..635075
                     /gene="dnaB"
                     /locus_tag="COSY_0612"
                     /EC_number="3.6.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="YP_001219449.1"
                     /db_xref="GI:148244755"
                     /db_xref="GeneID:5172684"
                     /translation="MNIKNTKIPPNSIESEQSVLGGLLLHNEAWDRVADILTQVDFYN
                     ASHKIIFNAISTLLQHDQPADILTVKEQVKKTDSEEIIGGFFYLAQIAENTPSISNIE
                     AYAKHVRELSVYRQLIIVSHQIADAAYHPKEVEVQELIDLSEKKIFEIAEQMTRGKQD
                     ITNIKDIIKDVVNRIQEMQEYSGINGLETGFIELDKLTSGLQNGDLIIIAGRPSMGKT
                     AFSMNIIEHIAITAKEPKPVVIFSLEMPTEQLVMRMISSFGHIEGSKLRNTMTETDWN
                     SFNHAVLALEKSTVLIDETPSITPIEIRAKCRRLKRQYPNLALIMVDYLQLMTVHGKN
                     ENRVQEISEISRSLKALAKEINVPVLALSQLNRGVESRLKANKGRMPQMVDLRESGSI
                     EQDADIIGFIYRDQQYHDDTYSNPEEIGKADLKIVKHRNGPTGIIKLAFIGEYARFED
                     LANEDQFHGMNDEQIDTTYAHNIANFDQEPF"
     misc_feature    633651..634988
                     /gene="dnaB"
                     /locus_tag="COSY_0612"
                     /note="replicative DNA helicase; Region: DnaB; TIGR00665"
                     /db_xref="CDD:233080"
     misc_feature    633651..633959
                     /gene="dnaB"
                     /locus_tag="COSY_0612"
                     /note="DnaB-like helicase N terminal domain; Region: DnaB;
                     pfam00772"
                     /db_xref="CDD:216111"
     misc_feature    634206..634952
                     /gene="dnaB"
                     /locus_tag="COSY_0612"
                     /note="DnaB helicase C terminal domain. The hexameric
                     helicase DnaB unwinds the DNA duplex at the  chromosome
                     replication fork. Although the mechanism by which DnaB
                     both couples ATP hydrolysis to translocation along DNA and
                     denatures the duplex is unknown, a...; Region: DnaB_C;
                     cd00984"
                     /db_xref="CDD:238484"
     misc_feature    634263..634283
                     /gene="dnaB"
                     /locus_tag="COSY_0612"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:238484"
     misc_feature    order(634278..634283,634596..634598,634719..634721,
                     634839..634841,634917..634919,634950..634952)
                     /gene="dnaB"
                     /locus_tag="COSY_0612"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238484"
     misc_feature    634587..634598
                     /gene="dnaB"
                     /locus_tag="COSY_0612"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:238484"
     misc_feature    order(634611..634616,634635..634643,634716..634742,
                     634836..634841,634887..634892)
                     /gene="dnaB"
                     /locus_tag="COSY_0612"
                     /note="DNA binding loops [nucleotide binding]"
                     /db_xref="CDD:238484"
     gene            635084..636139
                     /gene="alr"
                     /locus_tag="COSY_0613"
                     /db_xref="GeneID:5172255"
     CDS             635084..636139
                     /gene="alr"
                     /locus_tag="COSY_0613"
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="YP_001219450.1"
                     /db_xref="GI:148244756"
                     /db_xref="GeneID:5172255"
                     /translation="MSMCTIVSISQSALKHNLLVVKENSPNSKIVSMVKANAYGHKIN
                     LINPIINHSDLLAVSEISEAKKLRKITKKPILLLSGVIEDQELQQAIKLNCQIVVHDK
                     TQITTINNTKQPINIWIKINTGMHRLGLSTHEYFDCIKLLANNPLINTQCVMSHFACA
                     DEINHPMNQSQLFEFKKSTYHTTKRSMANSAAILSNPASHFDYVRPGIMLYGVSPFEI
                     INNHLKPVMQISAPIMSIKTIQTGDSVGYGATWIAKKSTTIATIGIGYGDGYPRHAKN
                     GTPVLINNNLCPLIGRVSMDLICVDISNVKASVGDNVILWGAQKLRIETIAKYSDTIA
                     YELLTGISSRVAFVSTI"
     misc_feature    635084..636127
                     /gene="alr"
                     /locus_tag="COSY_0613"
                     /note="Alanine racemase [Cell envelope biogenesis, outer
                     membrane]; Region: Alr; COG0787"
                     /db_xref="CDD:223858"
     misc_feature    635093..636133
                     /gene="alr"
                     /locus_tag="COSY_0613"
                     /note="Type III Pyridoxal 5-phosphate (PLP)-Dependent
                     Enzymes, Proteobacterial Alanine Racemases; Region:
                     PLPDE_III_AR_proteobact; cd06827"
                     /db_xref="CDD:143500"
     misc_feature    order(635180..635182,635186..635188,635198..635200,
                     635315..635317,635441..635443,635462..635464,
                     635543..635545,635549..635551,635648..635656,
                     635696..635707,636086..636088)
                     /gene="alr"
                     /locus_tag="COSY_0613"
                     /note="active site"
                     /db_xref="CDD:143500"
     misc_feature    order(635180..635182,635186..635188,635198..635200,
                     635315..635317,635549..635551,635648..635653,
                     635696..635698,635702..635707,636086..636088)
                     /gene="alr"
                     /locus_tag="COSY_0613"
                     /note="pyridoxal 5'-phosphate (PLP) binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:143500"
     misc_feature    order(635186..635188,635198..635200,635462..635464,
                     635549..635551,636086..636088)
                     /gene="alr"
                     /locus_tag="COSY_0613"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:143500"
     misc_feature    order(635186..635188,635822..635824)
                     /gene="alr"
                     /locus_tag="COSY_0613"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143500"
     misc_feature    order(635783..635785,635792..635794,635810..635815,
                     635819..635827,635864..635866,635879..635881,
                     635897..635899,635963..635965,635969..635971,
                     636080..636082,636086..636091,636104..636106,
                     636113..636115)
                     /gene="alr"
                     /locus_tag="COSY_0613"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143500"
     gene            636136..636837
                     /locus_tag="COSY_0614"
                     /db_xref="GeneID:5172048"
     CDS             636136..636837
                     /locus_tag="COSY_0614"
                     /note="serine/threonine protein phosphatase putative"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="YP_001219451.1"
                     /db_xref="GI:148244757"
                     /db_xref="GeneID:5172048"
                     /translation="MNYSLIQISDCHIDDNKYSMGVNTHINLKKIISRISHINIDVLL
                     ITGDLTHKGSITSYKALQQMLYPIQIKLLIIPGNHDNKNNLSATFSKNLFSQFTLGKW
                     EIININSVQVSKTSGFLTKDELIKLELNLAQSIAQYILITLHHPTVPMNSTWDDSLSL
                     ENPEALFNVLDKYHKIQAILFGHAHQAAEFKRLGVKIISCPSTALQFNNETRIGFNYY
                     TLYDNGQLTINTQWI"
     misc_feature    636148..636807
                     /locus_tag="COSY_0614"
                     /note="Enterobacter aerogenes GpdQ and related proteins,
                     metallophosphatase domain; Region: MPP_GpdQ; cd07402"
                     /db_xref="CDD:163645"
     misc_feature    636148..636693
                     /locus_tag="COSY_0614"
                     /note="Calcineurin-like phosphoesterase; Region:
                     Metallophos; pfam00149"
                     /db_xref="CDD:215750"
     misc_feature    order(636163..636165,636169..636171,636277..636279,
                     636286..636288,636367..636372,636565..636567,
                     636682..636684,636688..636690,636748..636750)
                     /locus_tag="COSY_0614"
                     /note="active site"
                     /db_xref="CDD:163645"
     misc_feature    order(636163..636165,636169..636171,636277..636279,
                     636367..636369,636565..636567,636682..636684,
                     636688..636690)
                     /locus_tag="COSY_0614"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163645"
     misc_feature    order(636202..636204,636211..636213,636220..636225,
                     636232..636237,636286..636288,636295..636297,
                     636322..636324,636577..636579,636583..636588,
                     636667..636669,636673..636675,636694..636708,
                     636715..636723,636727..636729,636790..636792,
                     636799..636801,636805..636807)
                     /locus_tag="COSY_0614"
                     /note="hexamer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:163645"
     gene            637054..637977
                     /locus_tag="COSY_0615"
                     /db_xref="GeneID:5172083"
     CDS             637054..637977
                     /locus_tag="COSY_0615"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase"
                     /protein_id="YP_001219452.1"
                     /db_xref="GI:148244758"
                     /db_xref="GeneID:5172083"
                     /translation="MKNTVKKNQEKNKLVITISSRALFNLDESHKIFKEQGVKAYTQH
                     QEENEKVILKPGVGFSLVKKLLALNTSQNPIDVILLSRNSADTSLRIFNSIENYGLNI
                     SKAAFTRGESTHNLVGAFGADLFLSSNYLDVQKALESGFAAASIVGSSSQKQHKTQLR
                     IAFDGDAVIFSDESERIFQEKGLKAFIENEKNSANIALKAGPFKCFVMSLQRIQSSFP
                     TINNPIRTALITARSAPSHKRVIHTMRKWGIRIDESFFLGGLEKGIFLKEFSADIFFD
                     DQHQHCQSASKYVPTGHVPNRISSQKIMLDK"
     misc_feature    637180..637956
                     /locus_tag="COSY_0615"
                     /note="5&apos;-nucleotidase; Region: 5-nucleotidase;
                     pfam06189"
                     /db_xref="CDD:218931"
     gene            638115..639053
                     /locus_tag="COSY_0616"
                     /db_xref="GeneID:5172653"
     CDS             638115..639053
                     /locus_tag="COSY_0616"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219453.1"
                     /db_xref="GI:148244759"
                     /db_xref="GeneID:5172653"
                     /translation="MSLQSVRMTLLQMLKIQVKIYILILAIIILNVLNPVQAEYIYNK
                     NLDLTEIPIKKALYKPFIERYILDELKLLRQEQQQLKVDFAEKVANARLDVSDRAIRY
                     TADTTTNIFYIITIAATLLVLLGWRSLQDVRDNIKTITSKQVSELTQKYEKRLSIIED
                     KARIRSEQIISTQQDIANTNLIHSLWVRSGIAKSEQEKINIFDEILDLAPDDIEALTY
                     KADTLLDIDEDTWSLSLSNRAIEIDDKYALAYWQRACAKAKLKQHDDAVADIKLATDL
                     TDSLKTEVMNEVYFENLKDNKKYQVLIGKFGNIENN"
     misc_feature    638709..638942
                     /locus_tag="COSY_0616"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cd00189"
                     /db_xref="CDD:238112"
     misc_feature    order(638718..638720,638727..638729,638772..638774,
                     638808..638810,638820..638822,638829..638831,
                     638874..638876,638910..638912,638922..638924,
                     638931..638933)
                     /locus_tag="COSY_0616"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     misc_feature    638745..638942
                     /locus_tag="COSY_0616"
                     /note="TPR repeat; Region: TPR_11; pfam13414"
                     /db_xref="CDD:222112"
     misc_feature    order(638763..638768,638772..638777,638784..638789,
                     638865..638870,638877..638882,638889..638894)
                     /locus_tag="COSY_0616"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     gene            complement(639500..639859)
                     /locus_tag="COSY_0617"
                     /db_xref="GeneID:5172668"
     CDS             complement(639500..639859)
                     /locus_tag="COSY_0617"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219454.1"
                     /db_xref="GI:148244760"
                     /db_xref="GeneID:5172668"
                     /translation="MQTPTNISLNKEKTLLTITFDKINYPLSAEYLRVYSPSAEVVGH
                     ASGQEILQLNKENVTILRIQPTGNYAVILFFSDKHDSGIYSWSHLHKLASNHDKLWHK
                     YLQKLKDIGHTHSQLNI"
     misc_feature    complement(639527..639859)
                     /locus_tag="COSY_0617"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3536"
                     /db_xref="CDD:226066"
     gene            640605..641873
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /db_xref="GeneID:5172637"
     CDS             640605..641873
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /EC_number="6.1.1.21"
                     /note="catalyzes a two-step reaction, first charging a
                     histidine molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA
                     synthetase; forms homodimers; some organisms have a
                     paralogous gene, hisZ, that is similar to hisS and
                     produces a protein that performs the first step in
                     histidine biosynthesis along with HisG"
                     /codon_start=1
                     /transl_table=11
                     /product="histidyl-tRNA synthetase"
                     /protein_id="YP_001219455.1"
                     /db_xref="GI:148244761"
                     /db_xref="GeneID:5172637"
                     /translation="MSKKIQAIRGMNDLLPKNSALWLSLEKTIFDLFITYGYQNIRTP
                     IVEKTDTFCRAIGGDTDIVEKEMYSWKETSGESLSLRPEGTAGCVRMMIEHNLPRESI
                     QKVFYQGAMFRHERPQKGRYRQFHQVGLEIFGVFNAKADAELMIIMHALWQTIGLKNI
                     VLEINTLGSNEVRNAYRKILVAYFNQHKNQLNEDGLKQLKTNPFRILDSKNKAIHSLI
                     SDAPKLMDYLDKKSIQHFKQFKSYLDALNITYVINTSLVRGLDYYNRTVFEWTTTDLG
                     TQSTICAGGRYDGLIEKMGGTPTPAVGLAIGLERLVLLLEAQNLISTKSTLSIYLIAF
                     GKKEQIKSIQIANVLHDELPNVILYNDLTLGSFKSQFEKADKAKANFALILGEQELNN
                     NQISIKPLRNQGTQQTMNLEEAIKYFKENQ"
     misc_feature    640614..641867
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /note="histidyl-tRNA synthetase; Reviewed; Region: hisS;
                     PRK00037"
                     /db_xref="CDD:234586"
     misc_feature    640659..641552
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /note="Class II Histidinyl-tRNA synthetase (HisRS)-like
                     catalytic core domain. HisRS is a homodimer. It is
                     responsible for the attachment of histidine to the 3&apos;
                     OH group of ribose of the appropriate tRNA. This domain is
                     primarily responsible for...; Region: HisRS-like_core;
                     cd00773"
                     /db_xref="CDD:238396"
     misc_feature    order(640671..640673,640707..640709,640722..640742,
                     640812..640817,640851..640853,640857..640859,
                     640872..640877,640884..640889,640971..640976,
                     640995..640997,641019..641021,641031..641033,
                     641040..641042,641457..641459,641511..641516)
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238396"
     misc_feature    640716..640742
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /note="motif 1; other site"
                     /db_xref="CDD:238396"
     misc_feature    order(640851..640853,640857..640859,640941..640943,
                     640947..640949,640968..640970,640977..640979,
                     640983..640985,640995..640997,641376..641378,
                     641382..641384,641388..641393,641442..641444,
                     641457..641459,641514..641516,641523..641525,
                     641532..641534)
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /note="active site"
                     /db_xref="CDD:238396"
     misc_feature    640938..640952
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /note="motif 2; other site"
                     /db_xref="CDD:238396"
     misc_feature    order(641511..641525,641532..641534)
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /note="motif 3; other site"
                     /db_xref="CDD:238396"
     misc_feature    641589..641861
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /note="HisRS Histidyl-anticodon binding domain. HisRS
                     belongs to class II aminoacyl-tRNA synthetases (aaRS).
                     This alignment contains the anticodon binding domain,
                     which is responsible for specificity in tRNA-binding, so
                     that the activated amino acid is...; Region:
                     HisRS_anticodon; cd00859"
                     /db_xref="CDD:238436"
     misc_feature    order(641604..641609,641718..641720,641736..641738,
                     641760..641762,641790..641792,641796..641798)
                     /gene="hisS"
                     /locus_tag="COSY_0618"
                     /note="anticodon binding site; other site"
                     /db_xref="CDD:238436"
     gene            641870..642487
                     /locus_tag="COSY_0619"
                     /db_xref="GeneID:5172353"
     CDS             641870..642487
                     /locus_tag="COSY_0619"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219456.1"
                     /db_xref="GI:148244762"
                     /db_xref="GeneID:5172353"
                     /translation="MRSFIKVNRTEEEQIKQTQQWIKKNTLQIIIAITVSLSGIWGFN
                     YYKKYQHSQTIKARDIYLTFRSKPHNIQVYEQLKNNHKNSIYLDHAILILAKNAVTNK
                     NYIQALEYLIPLNNTSNPSIAKVINMRIAGLHLEMGNYKKALDALNTVPNSTFNGLYN
                     QLKGDIYLANNNIDNAKKHYKLALNQISKNSELQNLIKIKLSDLN"
     misc_feature    641897..642481
                     /locus_tag="COSY_0619"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG2976"
                     /db_xref="CDD:225523"
     misc_feature    641906..642031
                     /locus_tag="COSY_0619"
                     /note="Uncharacterized protein conserved in bacteria
                     (DUF2133); Region: DUF2133; pfam09976"
                     /db_xref="CDD:204361"
     misc_feature    642137..642424
                     /locus_tag="COSY_0619"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cl02429"
                     /db_xref="CDD:243034"
     misc_feature    order(642137..642139,642143..642148,642155..642160,
                     642251..642256,642260..642265,642272..642277,
                     642347..642352,642362..642367,642374..642379)
                     /locus_tag="COSY_0619"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     misc_feature    order(642152..642154,642188..642190,642200..642202,
                     642260..642262,642296..642298,642308..642310,
                     642317..642319,642359..642361,642395..642397,
                     642407..642409,642416..642418)
                     /locus_tag="COSY_0619"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     gene            642494..643891
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /db_xref="GeneID:5172425"
     CDS             642494..643891
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="EngA; essential Neisserial GTPase; synchronizes
                     cellular events by interacting with multiple targets with
                     tandem G-domains; overexpression in Escherichia coli
                     suppresses rrmJ mutation; structural analysis of the
                     Thermotoga maritima ortholog shows different nucleotide
                     binding affinities in the two binding domains"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein EngA"
                     /protein_id="YP_001219457.1"
                     /db_xref="GI:148244763"
                     /db_xref="GeneID:5172425"
                     /translation="MGLPIICLIGRPNVGKSTLFNRLSHSRQALVSDFAGLTRDRQYA
                     KVLLNDDTQTFTTIIDTGGFTNKVNLVDSGIQDQILSALEESDVIYFILNSRDGVISL
                     DLEIASHLRRLKKNIILVCNKAEGLNPTLTTEFFELGLGKPILISAEHGQGIDNLINT
                     TLPLLPKVTVNEEVVEGITIAVLGKPNVGKSTLINHILREKRVIAIDLPGTTRDSIYI
                     PFERKGQQYTLIDTAGIRRKNSTHEKIEIFSIIKTINALERAHVVILVLDAQTGVTKQ
                     DASLLGMILDKDKALLIVINKWDGLDDYQKQEVKRKLEVKLSFISYTSVHYISALHGS
                     GVDKLFTPINQSYQDACKQHSTSILNKILDKANHGHQPPLVKGRRLKIKYVNQTNIFP
                     LTLAFHGNHLQNVPNAYERYLKKFFINSLKLTNIPIKIEYKSGNNPFKNKKNILNASQ
                     IAKKRRLMKFVKRKH"
     misc_feature    642500..643804
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="GTP-binding protein Der; Reviewed; Region:
                     PRK00093"
                     /db_xref="CDD:234628"
     misc_feature    642515..642988
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="EngA1 GTPase contains the first domain of EngA;
                     Region: EngA1; cd01894"
                     /db_xref="CDD:206681"
     misc_feature    642521..642544
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="G1 box; other site"
                     /db_xref="CDD:206681"
     misc_feature    order(642530..642532,642536..642547,642857..642862,
                     642866..642868,642932..642940)
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206681"
     misc_feature    order(642575..642595,642605..642616)
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206681"
     misc_feature    642605..642607
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="G2 box; other site"
                     /db_xref="CDD:206681"
     misc_feature    order(642704..642715,642746..642751)
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206681"
     misc_feature    642707..642715
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="G3 box; other site"
                     /db_xref="CDD:206681"
     misc_feature    642857..642868
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="G4 box; other site"
                     /db_xref="CDD:206681"
     misc_feature    642932..642940
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="G5 box; other site"
                     /db_xref="CDD:206681"
     misc_feature    643019..643534
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="EngA2 GTPase contains the second domain of EngA;
                     Region: EngA2; cd01895"
                     /db_xref="CDD:206682"
     misc_feature    643043..643066
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="G1 box; other site"
                     /db_xref="CDD:206682"
     misc_feature    order(643052..643054,643058..643069,643379..643384,
                     643388..643390,643478..643486)
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206682"
     misc_feature    order(643088..643090,643097..643138)
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206682"
     misc_feature    643127..643129
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="G2 box; other site"
                     /db_xref="CDD:206682"
     misc_feature    643184..643195
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="G3 box; other site"
                     /db_xref="CDD:206682"
     misc_feature    order(643193..643198,643268..643273)
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206682"
     misc_feature    643379..643390
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="G4 box; other site"
                     /db_xref="CDD:206682"
     misc_feature    643478..643486
                     /gene="engA"
                     /locus_tag="COSY_0620"
                     /note="G5 box; other site"
                     /db_xref="CDD:206682"
     gene            complement(644613..646250)
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /db_xref="GeneID:5172642"
     CDS             complement(644613..646250)
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /EC_number="6.3.4.2"
                     /note="CTP synthase; cytidine triphosphate synthetase;
                     catalyzes the ATP-dependent amination of UTP to CTP with
                     either L-glutamine or ammonia as the source of nitrogen;
                     in Escherichia coli this enzyme forms a homotetramer"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthetase"
                     /protein_id="YP_001219458.1"
                     /db_xref="GI:148244764"
                     /db_xref="GeneID:5172642"
                     /translation="MSTKYIFITGGVVSSLGKGIVSASLASILESRGLNITMLKLDPY
                     INVDPGTMSPFQHGEVFVTNDGAETDLDLGHYERFTRIQLGKENNFTAGRVYENVIER
                     ERLGKYLGDTVQVIPHITNEIKRLTQIGAKGADVTLVEIGGTAGDIESLPFMEAIRQM
                     SLELGRDNVLFIHLTLLPYIKVVGELKTKPTQHSVKELRSIGIQPDILICRSEYPMSD
                     IERAKIALFTNVSQDSVFTSLDVDTIYKVPRALHEQGLDNVVVKKLALDCKPTDLCEW
                     DNVIKRLQHPKSSVDIAMVGKYIDLTESYKSLSEALIHASIHTQTKVNIHYFDSEEIE
                     ENGTDCLSEMSAILVPGGFGNRGVEGKIATVKFARENNVPYLGICLGMQVAVIEYARN
                     MANMINANSTEFNKKTAYPVIHLITNWKDVDGYKHSLNKDSYLGGTMRLGGQKCVLVE
                     GTNSQEIYSKLVITERHRHRYEVNNLLIKQLEVSGLIVSGRSINGTLVEMIEIKDHPW
                     FVACQFHPEFTSNPRDGHPLFESFIKASNKANNLILF"
     misc_feature    complement(644637..646244)
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /note="CTP synthetase; Validated; Region: pyrG; PRK05380"
                     /db_xref="CDD:235437"
     misc_feature    complement(645483..646241)
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /note="CTP synthetase (CTPs) is a two-domain protein,
                     which consists of an N-terminal synthetase domain and
                     C-terminal glutaminase domain. The enzymes hydrolyze the
                     amide bond of glutamine to ammonia and glutamate at the
                     glutaminase domains and transfer nascent...; Region: CTGs;
                     cd03113"
                     /db_xref="CDD:239387"
     misc_feature    complement(order(645825..645827,645831..645833,
                     646023..646028,646035..646037,646041..646043,
                     646119..646127,646131..646133,646191..646202,
                     646209..646211))
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /note="Catalytic site [active]"
                     /db_xref="CDD:239387"
     misc_feature    complement(order(645582..645584,645684..645692,
                     645822..645824,646131..646133,646194..646208))
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /note="active site"
                     /db_xref="CDD:239387"
     misc_feature    complement(order(645582..645584,645684..645692,
                     645804..645806,645822..645827,646119..646133))
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /note="UTP binding site [chemical binding]; other site"
                     /db_xref="CDD:239387"
     misc_feature    complement(644652..645383)
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in Cytidine Triphosphate Synthetase; Region:
                     GATase1_CTP_Synthase; cd01746"
                     /db_xref="CDD:153217"
     misc_feature    complement(order(644700..644702,644706..644708,
                     644838..644849,645042..645044,645102..645104,
                     645111..645116,645189..645203))
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /note="active site"
                     /db_xref="CDD:153217"
     misc_feature    complement(order(645111..645113,645195..645197))
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /note="putative oxyanion hole; other site"
                     /db_xref="CDD:153217"
     misc_feature    complement(order(644700..644702,644706..644708,
                     645114..645116))
                     /gene="pyrG"
                     /locus_tag="COSY_0621"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153217"
     gene            646331..648052
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /db_xref="GeneID:5172525"
     CDS             646331..648052
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A export ATP-binding/permease protein
                     MsbA"
                     /protein_id="YP_001219459.1"
                     /db_xref="GI:148244765"
                     /db_xref="GeneID:5172525"
                     /translation="MQYKQFISHLFIHLKPHIGKFIFISTMMIIATVLESSVPEITGR
                     IVDELFATERKSETAFIYALTLLGAIVLSSLFALTSTAVSSWVSNKVIMDLRVIMFTK
                     LLKLPKSYLDQHPTGKTLSILTFDVEQIAASASTIWLDFIKSSMTVVILIGYLFYKNW
                     QLSLTLLILLPLVYLAVKFSSNRMRHSNVNVQKSMGDMTHLLNENISGNTLVKIYHAQ
                     SQINDKFNSLIKNIRQQRFKVDMTSSFNTAFVNILIGLSLSSVVYFSSTLLQMSAGEF
                     LSFFTAMGMLLKPAKSLVNINKPLQNAMAAGESVFGLINEKEESNIGTKELINPKGFI
                     QFNNVSFSYNNNTTILKHINLDIKAGETIAFVGATGSGKTTIIQLLMRFYSPKQGVIT
                     IDGVDINQFEIDSLRSNISFVDQNIQLFNDSIKGNIALGQLETISDKQIKQSAIIANA
                     DEFIQQLEHEFDTQIGENGISLSGGQRQRLAIARAIAKDSPILILDEATSALDNATEK
                     KVQNAIHKMQKNRTTIIIAHRLSTIQKANRIIVLRHGYIIEQGTHQELLDYQGEYAQL
                     YKHQFKY"
     misc_feature    646358..648046
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /note="lipid A export permease/ATP-binding protein MsbA;
                     Region: MsbA_lipidA; TIGR02203"
                     /db_xref="CDD:131258"
     misc_feature    646409..647191
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:216049"
     misc_feature    647330..648031
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    647429..647452
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(647438..647443,647447..647455,647573..647575,
                     647816..647821,647912..647914)
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    647564..647575
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    647744..647773
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    647804..647821
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    647828..647839
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    647900..647920
                     /gene="msbA"
                     /locus_tag="COSY_0622"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            complement(648228..648803)
                     /locus_tag="COSY_0623"
                     /db_xref="GeneID:5172707"
     CDS             complement(648228..648803)
                     /locus_tag="COSY_0623"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219460.1"
                     /db_xref="GI:148244766"
                     /db_xref="GeneID:5172707"
                     /translation="MIMESINTKHLFYSFILLNVSLVVYFYLNGYKIDLVMLKEFLSG
                     KNFLTSYLVYIIILIIRGLTFLPGAIFLLAGIYLFSFIQVFFAIQIAIVSYCLIIYNF
                     SHKLNFKVPEKILQFEQKIKSKEISIIFVLCFIPGISINVLIYFLSVIDIKLKNILIG
                     VIAGTSITSIIYISIITGIFNSSYYFSSFFK"
     gene            complement(648784..649683)
                     /locus_tag="COSY_0624"
                     /db_xref="GeneID:5172645"
     CDS             complement(648784..649683)
                     /locus_tag="COSY_0624"
                     /note="Similar to cyanophycin synthetase domain protein
                     CPS_3007 in Colwellia psychrerythraea 34H."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219461.1"
                     /db_xref="GI:148244767"
                     /db_xref="GeneID:5172645"
                     /translation="MKYWLHRFLSRFFLSGCSDYNPLKIRRACRSKAQARMAFKENNF
                     PYAQGKIFINPISAFKFAKKNGFPLVVKPNVGGFSRGAYFPINTYMQLAKASLSVKKW
                     WLVSIVEKYLLGKNYRIVMTKFGVMSVLRRYPPFVIGDNVSDIAKLIDNENLVRKKMN
                     LLPIIKPIPKNLAIKQYLKKQQMNLSSIPNVGQKVYLHHKISLKLGSSVEIIDKKILT
                     KQNRQDLKKILNFFDANILGIDVICKEGIEIDFNAQVCIFLELNSRPFLAMHNKPRYG
                     KSEDLSIFYHQLDKIQIFDHGEY"
     misc_feature    complement(<649333..649602)
                     /locus_tag="COSY_0624"
                     /note="ATP-grasp domain; Region: ATP-grasp_4; cl17255"
                     /db_xref="CDD:247809"
     gene            complement(649680..650489)
                     /locus_tag="COSY_0625"
                     /db_xref="GeneID:5172462"
     CDS             complement(649680..650489)
                     /locus_tag="COSY_0625"
                     /note="Similar to hypothetical protein CPS_3006 in
                     Colwellia psychrerythraea 34H."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219462.1"
                     /db_xref="GI:148244768"
                     /db_xref="GeneID:5172462"
                     /translation="MTFRLIFYYIYWSLRLGIPPWYYFQINAEWYNKKKGFYSKIDMD
                     KRIPLKWRLKQAYLDKNNPPCKFPVFLKPEWGQNSNGIKRIDSRDEFLAFNHKKSKIP
                     YIVQEVAIEMQEYEIFYIRNSDNETHCITLTITQVINHSGESYPVNSINNKQVIYQDC
                     TLDFSLRELKKLHNHLQELPYFRIARVGLRSNSKQDLLKGMFHIIEVNLFAPFPINLL
                     DSSISKKNKHQFIKDNMYHLVRISNTTPKEHFNRFVFFKKVIKHYQSKVEL"
     misc_feature    complement(<650145..>650291)
                     /locus_tag="COSY_0625"
                     /note="ATP-grasp domain; Region: ATP-grasp_4; cl17255"
                     /db_xref="CDD:247809"
     gene            complement(650479..650967)
                     /locus_tag="COSY_0626"
                     /db_xref="GeneID:5172464"
     CDS             complement(650479..650967)
                     /locus_tag="COSY_0626"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219463.1"
                     /db_xref="GI:148244769"
                     /db_xref="GeneID:5172464"
                     /translation="MFKEIQNTYYTHSTNFDFKMLCVLLHEEKYTLAIEKIKTLILEI
                     DLETLLFDQYNYTRNIIINNKSYWLGLLNWDKGAITRIHGHPDRAFIYVIKGQLICKD
                     FDKNPLTKISSSTLVDGTCKYSNSVKGKMDNDIHQISATELSLSLHFYSDNPIKGEIF
                     DF"
     misc_feature    complement(650515..>650817)
                     /locus_tag="COSY_0626"
                     /note="Cysteine dioxygenase type I; Region: CDO_I;
                     pfam05995"
                     /db_xref="CDD:218847"
     gene            complement(650960..652348)
                     /locus_tag="COSY_0627"
                     /db_xref="GeneID:5172466"
     CDS             complement(650960..652348)
                     /locus_tag="COSY_0627"
                     /note="Similar to the C-termnal region of glutamate
                     decarboxylase 1 (614 aa) in Strongylocentrotus
                     purpuratus."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219464.1"
                     /db_xref="GI:148244770"
                     /db_xref="GeneID:5172466"
                     /translation="MMQNQDVLQKITQVLATSNFKKSNQLINYQTINKLEKTLNLNKQ
                     NPQCWDEIFTWVEQYLEYSPNTSHPNFANRMWSGANQPSIVGEIVTALSNTSNCTFES
                     APVATLMERYMIKQMLDIVGFKNGEGQMTTGSSNANMIAMMVARNQALRKVKKQGLFN
                     QKYLFAFVNEDAHYSLDKASNILGIGTNHLIKVSTLEDGSINTILLNEKIKQIKQQGG
                     LVFFVCATLGTTVRGAYDNIEALTMLKKQHNFWLHGDGAWGGVAIMSLKLKKKFLTSI
                     ESLDSFTMDFHKMLGSNLMCNFLLLNHKHLLSCTCADGDGSYIFRDNEADLGIASLQC
                     GRRVDSLKWFLDWKFYTRKGFSDRVENYYQLAKFAEDFINASVDLEMVLKRTSFNVCF
                     RFKSSHSNKNNFNQCLRDSLYQGQQALLALAYVEKKLVFRLLISNINMNKVKLVSLLN
                     RLVKRGRTLNNV"
     misc_feature    complement(651170..652219)
                     /locus_tag="COSY_0627"
                     /note="Aspartate aminotransferase (AAT) superfamily (fold
                     type I) of pyridoxal phosphate (PLP)-dependent enzymes.
                     PLP combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine intermediate, which
                     depending on the reaction, is the...; Region: AAT_I;
                     cl00321"
                     /db_xref="CDD:241782"
     misc_feature    complement(order(651485..651487,651494..651496,
                     651575..651577,651584..651586,651671..651673,
                     651935..651937,651944..651949))
                     /locus_tag="COSY_0627"
                     /note="pyridoxal 5'-phosphate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:99742"
     misc_feature    complement(651485..651487)
                     /locus_tag="COSY_0627"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99742"
     gene            complement(652350..652811)
                     /locus_tag="COSY_0628"
                     /db_xref="GeneID:5172288"
     CDS             complement(652350..652811)
                     /locus_tag="COSY_0628"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219465.1"
                     /db_xref="GI:148244771"
                     /db_xref="GeneID:5172288"
                     /translation="MNNTIKVVAGWLVLLLVLYVFLSSLPYTFTSYAIESLYIFFTFG
                     AWMSYFLGGMISELFVQYSSYVINSSKLFTFLIVLSPIIFWYLRKDLHFISGLMVLVM
                     MYSVLFYLFILLNWIVKWNQNGQIQTDSGLVNVVFSILVLGVVMFLLNKRA"
     gene            complement(652856..653920)
                     /locus_tag="COSY_0629"
                     /db_xref="GeneID:5172429"
     CDS             complement(652856..653920)
                     /locus_tag="COSY_0629"
                     /note="Similar to anthranilate phosphoribosyltransferase
                     TrpD."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="YP_001219466.1"
                     /db_xref="GI:148244772"
                     /db_xref="GeneID:5172429"
                     /translation="MKISQKLIHSIIQRIATGPDLSKNIDFEEAKAGMLSILRGEINE
                     VQIAIFLIALRMKRETREESEGILAAILCESDQQQVIVDNLVDLGDPYSGYSRSIPIS
                     SFLPPLLAELGLPTVIHGLDSVSPKYGLTHRHINEALGLNINNSTKQAKVRLEDSSIG
                     WSYIDQENYCQGLHNLVPLRNKIIKRSVINTVETLIGPMRGKKTHSILGYVHKPYPPI
                     YAHLVTASGMDTSLLVRGVEGGVIPSLRQKGLMISYQGSVEQDKVDIDPKLLGIYQDI
                     RAISFPSGLNVYSDIKALADYTVKLGKSALSGEKGLFYDGLVLAASLILWHTRKASSL
                     IEAACITRAVLDSGKVLSRL"
     misc_feature    complement(653705..653899)
                     /locus_tag="COSY_0629"
                     /note="Glycosyl transferase family, helical bundle domain;
                     Region: Glycos_trans_3N; pfam02885"
                     /db_xref="CDD:145834"
     misc_feature    complement(652859..653890)
                     /locus_tag="COSY_0629"
                     /note="Anthranilate phosphoribosyltransferase [Amino acid
                     transport and metabolism]; Region: TrpD; COG0547"
                     /db_xref="CDD:223621"
     misc_feature    complement(652868..653629)
                     /locus_tag="COSY_0629"
                     /note="Glycosyl transferase family, a/b domain; Region:
                     Glycos_transf_3; pfam00591"
                     /db_xref="CDD:216013"
     gene            complement(653917..654213)
                     /locus_tag="COSY_0630"
                     /db_xref="GeneID:5172385"
     CDS             complement(653917..654213)
                     /locus_tag="COSY_0630"
                     /note="Similar to naphthalene 1,2-dioxygenase ferredoxin
                     component NirD."
                     /codon_start=1
                     /transl_table=11
                     /product="dioxygenase ferredoxin subunit"
                     /protein_id="YP_001219467.1"
                     /db_xref="GI:148244773"
                     /db_xref="GeneID:5172385"
                     /translation="MWVKILDKEPKEGEMVEVVVEGKDLFVTLNQGKLYCADNRCPHE
                     DIKLTLGCLKGDRIKCSLHGFSFDLITGNSTQKSVDNLRIYPIKQENNKIYLEL"
     misc_feature    complement(653923..>654120)
                     /locus_tag="COSY_0630"
                     /note="Rieske domain; a [2Fe-2S] cluster binding domain
                     commonly found in Rieske non-heme iron oxygenase (RO)
                     systems such as naphthalene and biphenyl dioxygenases, as
                     well as in plant/cyanobacterial chloroplast b6f and
                     mitochondrial cytochrome bc(1) complexes; Region: Rieske;
                     cl00938"
                     /db_xref="CDD:242206"
     misc_feature    complement(order(654013..654015,654019..654021,
                     654025..654030,654034..654036,654082..654087,
                     654091..654093))
                     /locus_tag="COSY_0630"
                     /note="iron-sulfur cluster [ion binding]; other site"
                     /db_xref="CDD:239550"
     misc_feature    complement(order(654019..654021,654025..654027,
                     654034..654036,654082..654087,654091..654093))
                     /locus_tag="COSY_0630"
                     /note="[2Fe-2S] cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239550"
     gene            complement(654219..654827)
                     /locus_tag="COSY_0631"
                     /db_xref="GeneID:5172538"
     CDS             complement(654219..654827)
                     /locus_tag="COSY_0631"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219468.1"
                     /db_xref="GI:148244774"
                     /db_xref="GeneID:5172538"
                     /translation="MVSKLLLIVLISLALSGCFSTPAIQVNNICHLMDEKVSWYQAVR
                     ASEKKYGIPMHVQLAIMYQESHFASNARPPRDKLFGVVPWFRQSSAYGFAQIRDITWE
                     WYQLKTGKQNINRNNFDDAINFIGWYANQSSKRSGIDKSDTYNQYLAYHDGHSGFNKQ
                     TYLVKPWLMKIAGGVDDNAKRYKHQLKQCAPRLDNNNIWKFF"
     misc_feature    complement(654342..654656)
                     /locus_tag="COSY_0631"
                     /note="Lytic Transglycosylase (LT)  and Goose Egg White
                     Lysozyme (GEWL) domain. Members include the soluble and
                     insoluble membrane-bound LTs in bacteria, the LTs in
                     bacteriophage lambda, as well as, the eukaryotic
                     &quot;goose-type&quot; lysozymes (GEWL).  LTs...; Region:
                     LT_GEWL; cd00254"
                     /db_xref="CDD:238157"
     misc_feature    complement(order(654378..654380,654444..654446,
                     654537..654539,654636..654638))
                     /locus_tag="COSY_0631"
                     /note="N-acetyl-D-glucosamine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238157"
     misc_feature    complement(654636..654638)
                     /locus_tag="COSY_0631"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238157"
     gene            complement(654821..655138)
                     /gene="csp"
                     /locus_tag="COSY_0632"
                     /db_xref="GeneID:5172276"
     CDS             complement(654821..655138)
                     /gene="csp"
                     /locus_tag="COSY_0632"
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein"
                     /protein_id="YP_001219469.1"
                     /db_xref="GI:148244775"
                     /db_xref="GeneID:5172276"
                     /translation="MVKKVQGTVAQFGTKGYGFIMGDDGEKYFVHQKNIFNKSRLKVN
                     TRVVFNTQNSEKGWVAMDVNLEKSIKTPNLKSKTLSYNTIKSMFVILFIIQAIIVYKI
                     FGW"
     misc_feature    complement(654950..655126)
                     /gene="csp"
                     /locus_tag="COSY_0632"
                     /note="Cold-Shock Protein (CSP) contains an S1-like
                     cold-shock domain (CSD) that is found in eukaryotes,
                     prokaryotes, and archaea.  CSP&apos;s include the major
                     cold-shock proteins CspA and CspB in bacteria and the
                     eukaryotic gene regulatory factor Y-box...; Region:
                     CSP_CDS; cd04458"
                     /db_xref="CDD:239905"
     misc_feature    complement(order(654971..654973,655052..655054,
                     655082..655084,655106..655108))
                     /gene="csp"
                     /locus_tag="COSY_0632"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:239905"
     misc_feature    complement(order(655046..655057,655073..655093))
                     /gene="csp"
                     /locus_tag="COSY_0632"
                     /note="RNA-binding motif; other site"
                     /db_xref="CDD:239905"
     gene            655781..656272
                     /locus_tag="COSY_0633"
                     /db_xref="GeneID:5172151"
     CDS             655781..656272
                     /locus_tag="COSY_0633"
                     /note="thiol-disulfide isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="YP_001219470.1"
                     /db_xref="GI:148244776"
                     /db_xref="GeneID:5172151"
                     /translation="MINHKKRKIFLQWLLVIIAIFSFRVYQQHDLSSGVIPSFNSKTL
                     SNVVVSSHSNKPTLIHFWATWCRICQLENDNIQTISSNYRVLNIAIQSGSDTDLKAYA
                     KEHDMKIDNIINDKSSSLAKLLGVKATPTSFFISKDNQIKFSEVGYVSMLGYRLRLWW
                     TSL"
     misc_feature    655889..656257
                     /locus_tag="COSY_0633"
                     /note="Protein Disulfide Oxidoreductases and Other
                     Proteins with a Thioredoxin fold; Region:
                     Thioredoxin_like; cl00388"
                     /db_xref="CDD:241832"
     misc_feature    655940..656203
                     /locus_tag="COSY_0633"
                     /note="Thioredoxin-like; Region: Thioredoxin_8; pfam13905"
                     /db_xref="CDD:222448"
     gene            656254..656928
                     /gene="ung"
                     /locus_tag="COSY_0634"
                     /db_xref="GeneID:5172529"
     CDS             656254..656928
                     /gene="ung"
                     /locus_tag="COSY_0634"
                     /EC_number="3.2.2.-"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="YP_001219471.1"
                     /db_xref="GI:148244777"
                     /db_xref="GeneID:5172529"
                     /translation="MVDKFMNIQNWHPSIKTLLKTQSIINLKLFLIRQRKAKKVILPN
                     SNNWFKAFELTAFDKVKVVILGQDPYHGLGQAHGLSFSVVHGVKKPPSLNNIFKELHN
                     DLNIEPKQNSNLTRWAIQGVLLLNSVLTVEVNKAASHSNQGWEVFTDSVIRTLSKEQQ
                     HLVFMLWGAHAKRKSILIDRNKHLILTSTHPSPLSAHRGFLGCRHFSKANNYLKIHNQ
                     QVINWQ"
     misc_feature    656347..656922
                     /gene="ung"
                     /locus_tag="COSY_0634"
                     /note="Family 1 of Uracil-DNA glycosylase (UDG) enzymes;
                     Region: UDG_F1; cd10027"
                     /db_xref="CDD:198425"
     misc_feature    order(656449..656463,656491..656496,656527..656529,
                     656629..656631,656821..656823)
                     /gene="ung"
                     /locus_tag="COSY_0634"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:198425"
     misc_feature    order(656452..656457,656461..656466,656521..656529,
                     656755..656760,656818..656823,656827..656838)
                     /gene="ung"
                     /locus_tag="COSY_0634"
                     /note="active site"
                     /db_xref="CDD:198425"
     misc_feature    order(656452..656454,656461..656469,656521..656529,
                     656656..656661,656755..656760,656821..656823,
                     656827..656835)
                     /gene="ung"
                     /locus_tag="COSY_0634"
                     /note="UGI interface [polypeptide binding]; other site"
                     /db_xref="CDD:198425"
     misc_feature    order(656455..656457,656821..656823)
                     /gene="ung"
                     /locus_tag="COSY_0634"
                     /note="catalytic site [active]"
                     /db_xref="CDD:198425"
     gene            656928..657965
                     /gene="pdxB"
                     /locus_tag="COSY_0635"
                     /db_xref="GeneID:5171891"
     CDS             656928..657965
                     /gene="pdxB"
                     /locus_tag="COSY_0635"
                     /EC_number="1.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="erythronate-4-phosphate dehyrogenase"
                     /protein_id="YP_001219472.1"
                     /db_xref="GI:148244778"
                     /db_xref="GeneID:5171891"
                     /translation="MKLVIDDACYAHKEIFSHFGNISTIAGRDINSTSVKNADILIVR
                     SRTKVNHVLLDGSQVKFVGSTVTGLDHIDQDYLKSKGIKFFSAQGCNSMAVAEFVISA
                     IVNLADELDFDYQKKTLGIIGIGNVGARLAKKAKLMGIKTLLNDPPRQMYENLPNFVD
                     LKTTLSADIVTFHTPLTVNGKYPSYQLLNENNFHYILDKTILFNVARGGIIKETIWQE
                     YKTLANIIDCWEDEPNINLKLQNTAYLATPHIAGHSIDAKFIGSFMVYEALCDFLGKK
                     QDSNIKNLINLDKLSINKDTLKNTLNKIYDFRQDAKAIQDINNFEDYRRNYPVRYEWH
                     HFKSKTTLPIA"
     misc_feature    656928..657938
                     /gene="pdxB"
                     /locus_tag="COSY_0635"
                     /note="erythronate-4-phosphate dehydrogenase; Validated;
                     Region: PRK00257"
                     /db_xref="CDD:166874"
     misc_feature    656931..657911
                     /gene="pdxB"
                     /locus_tag="COSY_0635"
                     /note="D-Erythronate-4-Phosphate Dehydrogenase NAD-binding
                     and catalytic domains; Region: ErythrP_dh; cd12158"
                     /db_xref="CDD:240635"
     misc_feature    order(657198..657200,657546..657548,657672..657674,
                     657684..657686,657897..657899)
                     /gene="pdxB"
                     /locus_tag="COSY_0635"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:240635"
     misc_feature    order(657198..657200,657210..657212,657291..657308,
                     657360..657371,657444..657452,657471..657473,
                     657477..657479,657540..657548,657606..657611,
                     657672..657674,657678..657683)
                     /gene="pdxB"
                     /locus_tag="COSY_0635"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:240635"
     misc_feature    order(657546..657548,657621..657623,657672..657674)
                     /gene="pdxB"
                     /locus_tag="COSY_0635"
                     /note="catalytic site [active]"
                     /db_xref="CDD:240635"
     misc_feature    order(657789..657797,657798..657806,657813..657815,
                     657822..657824,657834..657836,657843..657845,
                     657849..657854,657861..657863)
                     /gene="pdxB"
                     /locus_tag="COSY_0635"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240635"
     gene            complement(658536..660236)
                     /locus_tag="COSY_0636"
                     /db_xref="GeneID:5171871"
     CDS             complement(658536..660236)
                     /locus_tag="COSY_0636"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional serine/threonine kinase and
                     phosphatase"
                     /protein_id="YP_001219473.1"
                     /db_xref="GI:148244779"
                     /db_xref="GeneID:5171871"
                     /translation="MKQLKVIVNSHSIAGVKRENQDACAYYVPNPQTLQFKGIVGVIA
                     DGVSACERAKEASGCCVKGFLSDYYSTPESWSIEHSASTVISALNNWLYSQSMRFGEV
                     SSMLCTLSVVIIKSNAIHVFHVGDSRVYRYRNKVLRQLTKDHILSLNKEKTYLSRAMG
                     FDLSINVDYQIFDLELGDQFLMTTDGVHDYLQHASLASLMDKDSSAHKIVEQAIKKNS
                     QDNISAMIIMIEQLPDKNLGEVFDELTQKPVPPDLTKGMKINGFEIESLIISSAKMQL
                     YLAKDIMTKQLVALKTPSVNFEDDPEYLQHFMYEKWVGQRVKSPNVVKIYNSYKKANF
                     LAYAMVYVKGQTLRSWMNGNKQPNIEVVVSFVKQIIQGLRAFHRQEMLHCDLKPENIM
                     INEIGQIKIIDFGSVRIAGVSELVNPINFIGNQGTQGYTAPEVILNEIVSQASDQFSL
                     GVIVYEIFSSHIPYQNKLDKNLSVKTLSKLTYESVLIYNSNLPVWIDGAIHKACYLDY
                     MNRYEALSDFLYDLEHPNSIFLLPKKNKQSKLKPIKYRLLSVLLLVLNFILLLILFIK
                     "
     misc_feature    complement(659556..660221)
                     /locus_tag="COSY_0636"
                     /note="Serine/threonine phosphatases, family 2C, catalytic
                     domain; The protein architecture and deduced catalytic
                     mechanism of PP2C phosphatases are similar to the PP1,
                     PP2A, PP2B family of protein Ser/Thr phosphatases, with
                     which PP2C shares no sequence...; Region: PP2Cc; cd00143"
                     /db_xref="CDD:238083"
     misc_feature    complement(order(659577..659579,659682..659684,
                     660096..660104,660171..660176,660186..660188))
                     /locus_tag="COSY_0636"
                     /note="active site"
                     /db_xref="CDD:238083"
     misc_feature    complement(658788..659408)
                     /locus_tag="COSY_0636"
                     /note="Serine/Threonine protein kinases, catalytic domain;
                     Region: S_TKc; smart00220"
                     /db_xref="CDD:214567"
     misc_feature    complement(658866..659408)
                     /locus_tag="COSY_0636"
                     /note="Catalytic domain of Protein Kinases; Region: PKc;
                     cd00180"
                     /db_xref="CDD:173623"
     misc_feature    complement(order(658950..658961,659019..659021,
                     659028..659030,659061..659063,659067..659072,
                     659076..659078,659082..659084,659193..659195,
                     659199..659201,659211..659222,659268..659270,
                     659364..659366,659370..659372))
                     /locus_tag="COSY_0636"
                     /note="active site"
                     /db_xref="CDD:173623"
     misc_feature    complement(order(659028..659030,659061..659063,
                     659067..659072,659076..659078,659082..659084,
                     659199..659201,659211..659222,659268..659270,
                     659364..659366,659370..659372))
                     /locus_tag="COSY_0636"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:173623"
     misc_feature    complement(order(658950..658961,659019..659021,
                     659070..659072,659076..659078,659082..659084,
                     659193..659195,659199..659201))
                     /locus_tag="COSY_0636"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173623"
     misc_feature    complement(order(658950..658961,659013..659033))
                     /locus_tag="COSY_0636"
                     /note="activation loop (A-loop); other site"
                     /db_xref="CDD:173623"
     gene            complement(660239..661705)
                     /locus_tag="COSY_0637"
                     /db_xref="GeneID:5172501"
     CDS             complement(660239..661705)
                     /locus_tag="COSY_0637"
                     /note="nitrate/nitrite porter (NNP) family in major
                     facilitator superfamily (MFS)"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter"
                     /protein_id="YP_001219474.1"
                     /db_xref="GI:148244780"
                     /db_xref="GeneID:5172501"
                     /translation="MEDKLNLFSFKGKYYILHLTWFAFFMTFVVWLSLGPMMPFIQQA
                     LLLSEQQAKVLLILNVAMTIPARIVVGMLVDKLGPKIMFSSILVLGGFVSIVFSWMQS
                     YEQLALVRFLSGFIGAGFVVGIRMISEWFPAKQTGTAQGIYGGWGNFGSAGAAISLPF
                     IASSFGEVNGWRYAITIASMLAISYGIFYYFNVTNTPKGSTYFKPKKIGAMEVSSYSD
                     LGLYVLMNIPLYLALSLLTWKLSPERMNMISLGVEFSIYIVLVLVFVLQIFKTWTVNA
                     QYLKHFTLKQHQYKFKQVAILDWAYLVTFGAELSVVSILAMFYVDWFELPKITAALLA
                     GVYPFINLFARPGGGYLSDKYGRKLTLVVLFSGITLSFLVLGNVDKSWSMYLVVALTI
                     VGGIFSKAGSGAVFSMVPLIQRRLTGQIAGMVGAFGNVGAVLFLTANSLVDYDEFFIL
                     ISMTSAVVLVLIVIFLEEPKEHMTEILDDGTVEIIKLN"
     misc_feature    complement(660410..661660)
                     /locus_tag="COSY_0637"
                     /note="nitrite extrusion protein (nitrite facilitator);
                     Region: 2A0108; TIGR00886"
                     /db_xref="CDD:233170"
     misc_feature    complement(<661133..661651)
                     /locus_tag="COSY_0637"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(order(661253..661255,661271..661276,
                     661283..661288,661322..661324,661331..661336,
                     661343..661348,661355..661360,661493..661498,
                     661502..661507,661517..661519,661526..661531,
                     661538..661540,661589..661594,661598..661606,
                     661613..661615))
                     /locus_tag="COSY_0637"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     misc_feature    complement(<660380..660799)
                     /locus_tag="COSY_0637"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(order(660410..660412,660428..660433,
                     660440..660445,660485..660487,660494..660499,
                     660506..660511,660518..660523,660659..660664,
                     660668..660673,660683..660685,660692..660697,
                     660704..660706,660755..660760,660764..660772,
                     660779..660781))
                     /locus_tag="COSY_0637"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(661708..664077)
                     /gene="nirB"
                     /locus_tag="COSY_0638"
                     /db_xref="GeneID:5172717"
     CDS             complement(661708..664077)
                     /gene="nirB"
                     /locus_tag="COSY_0638"
                     /EC_number="1.7.1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase (NAD(P)H) large subunit"
                     /protein_id="YP_001219475.1"
                     /db_xref="GI:148244781"
                     /db_xref="GeneID:5172717"
                     /translation="MKNLVIVGSGMSAMKVVDEVLNIDPMMYQIIIIGEEKVLPYNRI
                     MLSLVLAGEKEFEDIKTHNESYFSQNNIIFKPGCLVSSIDRFNKNILLTNKKESYSIK
                     YDRLVICTGSRPVILPLPGKTLEGVVSFRDIYDVEYMQSKVNQAKKVVVIGTGLLGLE
                     AANGLNELGFDVTVIGNMDSIMNMQLDALSGDLLQKVLEQKNIKFKLGMIINKIIGFN
                     KVKALEFKGGIIMDADMVIMSVGIIPEDSLAKAAGLHTDRGIIVGDTMMTSDPAIYSV
                     GECIKHRGISYGLVAPLFEQARVCAEQICEVSHHIYTGSNISTKLKISGVDVFSAGEF
                     NNPKDEIMCSKDNAFNTRKRLSIRDNKLVGAVLFGDSTDGLFYFNLIKKETDISSIRK
                     TLLFGNINDLGVGDKGVEKMANDEQVCGCMGVDKGDIVSAVAGGCNTFEALQEETGCS
                     TGCGGCTSVAKQVFSFVSGTKILSKNTLCNCTKYSTEEVRQYIRVLVQVVSVDNVRDA
                     LDFDNTCEICGAAINYYLSSQFNETYLHNDDERPHNEKMHANKQRDGTYSVVPQMQGG
                     LTTPKELKALADIAIKYEVPTVKVTGGQRIDLLGVSKENLNDIWDEVTGAGMEAGYAY
                     AKATRTCKSCVGKDHCMMGTQDSMGLAIKMEDAVWSHFMPHKFKMGVSGCPRNCAEVT
                     IKDFGVICTEKGYEIHVAGACGIRTKTCLKDRFFETEEEVVEYLKAFVQLYRIEANYL
                     ERVMHFEERVGLDYIQSKLDTSSMIKYYANLLPKTVKNPWGITTHKSSV"
     misc_feature    complement(661807..664068)
                     /gene="nirB"
                     /locus_tag="COSY_0638"
                     /note="NAD(P)H-nitrite reductase [Energy production and
                     conversion]; Region: NirB; COG1251"
                     /db_xref="CDD:224171"
     misc_feature    complement(663394..663636)
                     /gene="nirB"
                     /locus_tag="COSY_0638"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:215691"
     misc_feature    complement(662242..662427)
                     /gene="nirB"
                     /locus_tag="COSY_0638"
                     /note="Nitrite/Sulfite reductase ferredoxin-like half
                     domain; Region: NIR_SIR_ferr; pfam03460"
                     /db_xref="CDD:217572"
     gene            664377..664826
                     /gene="moaE"
                     /locus_tag="COSY_0639"
                     /db_xref="GeneID:5171963"
     CDS             664377..664826
                     /gene="moaE"
                     /locus_tag="COSY_0639"
                     /note="molybdopterin converting factor, subunit 2"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein E"
                     /protein_id="YP_001219476.1"
                     /db_xref="GI:148244782"
                     /db_xref="GeneID:5171963"
                     /translation="MDKIIIQQQDFDLSTEVALIKNTRSDIGAIVSFVGFVRELKDNQ
                     IQKMTLEYYPGMTEKTLKYIVNKANKLWHISNTTIIHRVGDLNIKDQIVLVITSSKHR
                     QTAFESCEFIMDFLKTQAPFWKKEHTQNKSTWVEAKSSDKNQKKRWE"
     misc_feature    664407..664781
                     /gene="moaE"
                     /locus_tag="COSY_0639"
                     /note="MoaE family. Members of this family are involved in
                     biosynthesis of the molybdenum cofactor (Moco), an
                     essential cofactor for a diverse group of redox enzymes.
                     Moco biosynthesis is an evolutionarily conserved pathway
                     present in eubacteria, archaea and...; Region: MoaE;
                     cd00756"
                     /db_xref="CDD:238385"
     misc_feature    order(664425..664427,664437..664439,664458..664460,
                     664464..664478,664482..664484,664488..664490,
                     664647..664649,664674..664676,664680..664682,
                     664704..664706,664716..664718)
                     /gene="moaE"
                     /locus_tag="COSY_0639"
                     /note="MoaE homodimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238385"
     misc_feature    order(664527..664529,664533..664535,664542..664544,
                     664551..664553,664563..664565,664617..664619,
                     664725..664730,664734..664736,664740..664748,
                     664776..664778)
                     /gene="moaE"
                     /locus_tag="COSY_0639"
                     /note="MoaD interaction [polypeptide binding]; other site"
                     /db_xref="CDD:238385"
     misc_feature    order(664725..664727,664746..664748)
                     /gene="moaE"
                     /locus_tag="COSY_0639"
                     /note="active site residues [active]"
                     /db_xref="CDD:238385"
     gene            complement(664829..665413)
                     /gene="mobA"
                     /locus_tag="COSY_0640"
                     /db_xref="GeneID:5172065"
     CDS             complement(664829..665413)
                     /gene="mobA"
                     /locus_tag="COSY_0640"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein A"
                     /protein_id="YP_001219477.1"
                     /db_xref="GI:148244783"
                     /db_xref="GeneID:5172065"
                     /translation="MKNIGKSDITVVILAGGQSIRMNHKDKGLILFNGKPLISYVVDI
                     VHQDVCSILISANRNISEYQRFGEVITDSLPGFQGPLAGILSALNKVKTKYLLIVPCD
                     GPFINQSLITRLLKNMQQPSVNICVAMQGQKMHPTFSLVSVNLKDNLSEFLEQGNRKM
                     SVWFESNHAQKVDFSDQVNMFTNLNSPKDLKIKQ"
     misc_feature    complement(664841..665395)
                     /gene="mobA"
                     /locus_tag="COSY_0640"
                     /note="molybdopterin-guanine dinucleotide biosynthesis
                     protein MobA; Reviewed; Region: mobA; PRK00317"
                     /db_xref="CDD:234725"
     misc_feature    complement(664844..665389)
                     /gene="mobA"
                     /locus_tag="COSY_0640"
                     /note="MobA catalyzes the formation of molybdopterin
                     guanine dinucleotide; Region: MobA; cd02503"
                     /db_xref="CDD:133000"
     misc_feature    complement(order(665108..665110,665114..665116,
                     665165..665167,665174..665179,665198..665200,
                     665249..665251,665333..665335,665360..665362,
                     665366..665374))
                     /gene="mobA"
                     /locus_tag="COSY_0640"
                     /note="GTP binding site; other site"
                     /db_xref="CDD:133000"
     gene            665492..666763
                     /gene="moeA"
                     /locus_tag="COSY_0641"
                     /db_xref="GeneID:5172061"
     CDS             665492..666763
                     /gene="moeA"
                     /locus_tag="COSY_0641"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin biosynthesis protein MoeA"
                     /protein_id="YP_001219478.1"
                     /db_xref="GI:148244784"
                     /db_xref="GeneID:5172061"
                     /translation="MIDNQHQVDYESDQTPEFLHSINKALEKLISLAKVIDSTQLIEL
                     DDALNRILAVDIHANISVPSFNNSAMDGYAINLKENQINTPGKFVFEITDRISAGNTV
                     SILEPGCAARIFTGAPIPNGANTVLVQEECKVIKNKFKIKVDRPILLNENIRPIGNDI
                     QSGDVILSKGKQLQPQDIALASSIGIGKFEVFNKIKVGVFFTGDELVKPGNTLQQGQI
                     FNSNRYLLVALLNKLSCNIINLGNIKDTLNATCDALETLKSNCDLIITTGGVSIGDKD
                     YIKPAIEKLGQLNLWRIKIKPGKPIAFGNIGHCTFIGLPGNPVSAMVTFLLFARPFIK
                     KIQGANHYLNNALKTQTNFDWHKPKPRCEFVRVCLDHTTFPAKANIYTKQGSNVLSSM
                     VWADGLMEIPEKTTFKKGEILNFYSLNEMLS"
     misc_feature    665546..666754
                     /gene="moeA"
                     /locus_tag="COSY_0641"
                     /note="Molybdopterin biosynthesis enzyme [Coenzyme
                     metabolism]; Region: MoeA; COG0303"
                     /db_xref="CDD:223380"
     misc_feature    665564..666745
                     /gene="moeA"
                     /locus_tag="COSY_0641"
                     /note="MoeA family. Members of this family are involved in
                     biosynthesis of the molybdenum cofactor (MoCF), an
                     essential cofactor of a diverse group of redox enzymes.
                     MoCF biosynthesis is an evolutionarily conserved pathway
                     present in eubacteria, archaea and...; Region: MoeA;
                     cd00887"
                     /db_xref="CDD:238452"
     misc_feature    order(665624..665626,665966..665968,666011..666022,
                     666026..666028,666035..666040,666044..666046,
                     666146..666148,666152..666154,666161..666163,
                     666530..666532,666650..666652,666731..666733)
                     /gene="moeA"
                     /locus_tag="COSY_0641"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238452"
     misc_feature    order(666095..666100,666104..666106,666224..666226,
                     666296..666298)
                     /gene="moeA"
                     /locus_tag="COSY_0641"
                     /note="putative functional site; other site"
                     /db_xref="CDD:238452"
     misc_feature    order(666296..666304,666434..666439,666449..666451,
                     666458..666460)
                     /gene="moeA"
                     /locus_tag="COSY_0641"
                     /note="putative MPT binding site; other site"
                     /db_xref="CDD:238452"
     gene            666760..667266
                     /gene="moaC"
                     /locus_tag="COSY_0642"
                     /db_xref="GeneID:5172059"
     CDS             666760..667266
                     /gene="moaC"
                     /locus_tag="COSY_0642"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein C"
                     /protein_id="YP_001219479.1"
                     /db_xref="GI:148244785"
                     /db_xref="GeneID:5172059"
                     /translation="MNNKQNIVIQTNKLTHINNKGKSNMVDISNKNTTTRIAKATAKV
                     VMKLETLQKIKNNDFKKGDVLSVARIAGIMAAKQTHNLIPMCHSLNLSKINIDFKFVK
                     NGIQITTLAKLNAKTGVEMEALTAASIAALTIYDMCKSVDHFIKIKDIQLLEKQGGKS
                     GYWKLEYV"
     misc_feature    666832..667245
                     /gene="moaC"
                     /locus_tag="COSY_0642"
                     /note="MoaC family, prokaryotic and eukaryotic. Members of
                     this family are involved in molybdenum cofactor (Moco)
                     biosynthesis, an essential cofactor of a diverse group of
                     redox enzymes. MoaC, a small hexameric protein, converts,
                     together with MoaA, a guanosine...; Region: MoaC_PE;
                     cd01420"
                     /db_xref="CDD:238708"
     misc_feature    order(666832..666843,666946..667023,667030..667050,
                     667198..667233)
                     /gene="moaC"
                     /locus_tag="COSY_0642"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238708"
     misc_feature    order(666940..666948,666994..667008,667183..667191)
                     /gene="moaC"
                     /locus_tag="COSY_0642"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238708"
     misc_feature    order(666940..666942,666988..666990,667009..667011,
                     667015..667020,667108..667110,667117..667125,
                     667132..667134,667165..667167,667174..667176)
                     /gene="moaC"
                     /locus_tag="COSY_0642"
                     /note="putative active site [active]"
                     /db_xref="CDD:238708"
     gene            667259..668254
                     /gene="moaA"
                     /locus_tag="COSY_0643"
                     /db_xref="GeneID:5172069"
     CDS             667259..668254
                     /gene="moaA"
                     /locus_tag="COSY_0643"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein A"
                     /protein_id="YP_001219480.1"
                     /db_xref="GI:148244786"
                     /db_xref="GeneID:5172069"
                     /translation="MFKLIDKFGRKINYLRLSVTEHCNYRCFYCRDNKYTPHCKREDI
                     LSYKDIERIVQLFAQLGISKVRLTGGEPLLRKDIYKIARIISHVDGINDIPLSTNAHL
                     LEKFAKKLYQNGINRVNISIDSLIPKKFEEITRGGNLTKVIKGIDAAIQVNMRPIKIN
                     MVTMRGVNDNEIESMIDFAINKGIDIRFIETMPIGSSGIKILTHYISEKNILTKINNH
                     LNNKLVPIASSDIDGPAHNFKIMGTNSTIGTISAMSNHFCQTCNRVRLTAKGDLILCL
                     GQKNSISLKDALHSNLTDDQIKNIIINAINKKPEKHEFNSVVDNISNRQMVEIGG"
     misc_feature    667268..668251
                     /gene="moaA"
                     /locus_tag="COSY_0643"
                     /note="molybdenum cofactor biosynthesis protein A;
                     Reviewed; Region: moaA; PRK00164"
                     /db_xref="CDD:234672"
     misc_feature    667307..667852
                     /gene="moaA"
                     /locus_tag="COSY_0643"
                     /note="Radical SAM superfamily. Enzymes of this family
                     generate radicals by combining a 4Fe-4S cluster and
                     S-adenosylmethionine (SAM) in close proximity. They are
                     characterized by a conserved CxxxCxxC motif, which
                     coordinates the conserved iron-sulfur cluster; Region:
                     Radical_SAM; cd01335"
                     /db_xref="CDD:100105"
     misc_feature    order(667325..667327,667331..667333,667337..667339,
                     667343..667351,667460..667462,667466..667471,
                     667547..667555,667619..667621,667748..667750,
                     667835..667840)
                     /gene="moaA"
                     /locus_tag="COSY_0643"
                     /note="FeS/SAM binding site; other site"
                     /db_xref="CDD:100105"
     misc_feature    667808..668197
                     /gene="moaA"
                     /locus_tag="COSY_0643"
                     /note="Molybdenum Cofactor Synthesis C; Region:
                     Mob_synth_C; pfam06463"
                     /db_xref="CDD:115139"
     gene            668273..668509
                     /gene="moaD"
                     /locus_tag="COSY_0644"
                     /db_xref="GeneID:5172333"
     CDS             668273..668509
                     /gene="moaD"
                     /locus_tag="COSY_0644"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein D"
                     /protein_id="YP_001219481.1"
                     /db_xref="GI:148244787"
                     /db_xref="GeneID:5172333"
                     /translation="MNILYFASLKESLNLSSEKIILADNTTITQLRTQLINKYGKHNF
                     PNNTICAVNQEIANDAVIIKKTDEVAFYPPVTGG"
     misc_feature    668273..668506
                     /gene="moaD"
                     /locus_tag="COSY_0644"
                     /note="Ubiquitin domain of MoaD-like proteins; Region:
                     MoaD; cd00754"
                     /db_xref="CDD:176354"
     misc_feature    order(668288..668296,668300..668305,668429..668431,
                     668474..668476,668489..668497,668504..668506)
                     /gene="moaD"
                     /locus_tag="COSY_0644"
                     /note="MoaE interaction surface [polypeptide binding];
                     other site"
                     /db_xref="CDD:176354"
     misc_feature    order(668288..668293,668300..668305,668489..668491,
                     668495..668497,668504..668506)
                     /gene="moaD"
                     /locus_tag="COSY_0644"
                     /note="MoeB interaction surface [polypeptide binding];
                     other site"
                     /db_xref="CDD:176354"
     misc_feature    668504..668506
                     /gene="moaD"
                     /locus_tag="COSY_0644"
                     /note="thiocarboxylated glycine; other site"
                     /db_xref="CDD:176354"
     gene            complement(669306..669758)
                     /locus_tag="COSY_0645"
                     /db_xref="GeneID:5172067"
     CDS             complement(669306..669758)
                     /locus_tag="COSY_0645"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219482.1"
                     /db_xref="GI:148244788"
                     /db_xref="GeneID:5172067"
                     /translation="MSIKVNHVQISDDDVFQEMQYQTDAINVKEVIFKAAQALVVQQL
                     LLQAVGIKKNNPNEEEKINQLLSDNIVIPTASVEFCKRYYNNNKIKFLDKERGETLPF
                     EMVKVYIKEYLQNQSTISGINEYIKMLAVDANIQGFDFKDPSVTNIKI"
     gene            complement(669765..670445)
                     /gene="narI"
                     /locus_tag="COSY_0646"
                     /db_xref="GeneID:5172556"
     CDS             complement(669765..670445)
                     /gene="narI"
                     /locus_tag="COSY_0646"
                     /EC_number="1.7.99.4"
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase gamma subunit"
                     /protein_id="YP_001219483.1"
                     /db_xref="GI:148244789"
                     /db_xref="GeneID:5172556"
                     /translation="MNTFLDQFFFGYYPYVAMTMFIVGSALRYDRDQYTWKADSSQLL
                     RKKGMLWGSNLFHIGIILLFFGHFVGLLTPEWVYHPFMSAGTKQIIAMTVGSIFGTMC
                     LVGMLILLNRRLFDKRIRKTSKFSDTFILIYLFVQLLLGLLTVPYSTQHLDGSSMIAL
                     ANWAQYITSFRMGATDFIVSEAWVFKLHLILGMTLFAIFPFTRLVHIWSVPVQYLTRT
                     NYQIVRRR"
     misc_feature    complement(669768..670436)
                     /gene="narI"
                     /locus_tag="COSY_0646"
                     /note="Nitrate reductase gamma subunit; Region:
                     Nitrate_red_gam; pfam02665"
                     /db_xref="CDD:145687"
     gene            complement(670461..671117)
                     /gene="narJ"
                     /locus_tag="COSY_0647"
                     /db_xref="GeneID:5171982"
     CDS             complement(670461..671117)
                     /gene="narJ"
                     /locus_tag="COSY_0647"
                     /EC_number="1.7.99.4"
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase delta subunit"
                     /protein_id="YP_001219484.1"
                     /db_xref="GI:148244790"
                     /db_xref="GeneID:5171982"
                     /translation="MKILKVLAVLLSYPNINVYKNIDELTEVLKQESLLSKKKIKELL
                     SFIEDYKNKDLLELQERFVATFDRSRIHCLNLFEHIHGESRDRGQAMVDLIDMYAKKN
                     LFIDKKELPDYLPLFLEYLSLCDVQEAITSLGDTVDIIALIGGHLKKNKSPYQIIFFA
                     LEELSNIKANQFKVAEAIENSLKEPETLDELDELWQEQEAFSGDSSECSACEINATKN
                     "
     misc_feature    complement(670578..671117)
                     /gene="narJ"
                     /locus_tag="COSY_0647"
                     /note="Nitrate reductase delta subunit [Energy production
                     and conversion]; Region: NarJ; COG2180"
                     /db_xref="CDD:225091"
     gene            complement(671114..672655)
                     /gene="narH"
                     /locus_tag="COSY_0648"
                     /db_xref="GeneID:5171979"
     CDS             complement(671114..672655)
                     /gene="narH"
                     /locus_tag="COSY_0648"
                     /EC_number="1.7.99.4"
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase beta subunit"
                     /protein_id="YP_001219485.1"
                     /db_xref="GI:148244791"
                     /db_xref="GeneID:5171979"
                     /translation="MRIRAQIGMVLNLDKCIGCHTCSVTCKNVWTSRQGVEYAWFNNV
                     ETKPGIGYPVDWENQDKWNGGWVSKNGKLQPKIGGKFRLLAKIFANPDLPEIDDYYEP
                     FTFNYAHLQNAPEMITPPVARPHSMITGEVMEKPEWGPNWEEILGGEFKKRSKDYNFK
                     TIEKEIYGQFENTFMMYLPRLCEHCLNPSCVAACPSGAIYKREEDGIVLIDQDKCRGW
                     RMCVSACPYKKIYYNWQSGKSEKCTFCYPRIESGEPTVCSETCVGRIRSLGVILYDAD
                     KIEEMANMSDEKDLYEAQLKIFLDPNDKSIQAEAKKDGIPDSWIEAAQNSPVYKMAID
                     WKVAFPLHPEYRTLPMVWYIPPLSPIQNAIEKGVINNRGPIPNVEELRIPIRYLANML
                     TAGDDKPIIFALKRMIAMRNFMRAKRVDNVILTEVLDEVGLTEDMVDDMYRTMALAAY
                     EDRFVIPTNHKEYAGEMPFDNEIAFDTRSSCGFSFGNGCSEGSTTATLFGGKTHSNTM
                     NGNIS"
     misc_feature    complement(671150..672655)
                     /gene="narH"
                     /locus_tag="COSY_0648"
                     /note="Nitrate reductase beta subunit [Energy production
                     and conversion]; Region: NarY; COG1140"
                     /db_xref="CDD:224063"
     misc_feature    complement(671966..672037)
                     /gene="narH"
                     /locus_tag="COSY_0648"
                     /note="4Fe-4S binding domain; Region: Fer4_6; pfam12837"
                     /db_xref="CDD:205098"
     gene            complement(672655..676386)
                     /gene="narG"
                     /locus_tag="COSY_0649"
                     /db_xref="GeneID:5171983"
     CDS             complement(672655..676386)
                     /gene="narG"
                     /locus_tag="COSY_0649"
                     /EC_number="1.7.99.4"
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase alpha subunit"
                     /protein_id="YP_001219486.1"
                     /db_xref="GI:148244792"
                     /db_xref="GeneID:5171983"
                     /translation="MSYLLDRITFFTQSKPEYFSNGHGKLVHENRSWEKAYRNRWGHD
                     KVVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTNYPRTRPDLPDHEPRGCQRGATYSW
                     YLYSATRLKYPLIRSRLLKIWREAKKQNIDPVDAWKSIMNDKAKTKEYKQVRGLGGMV
                     RVDWDEVNEIIVASNIYTTKTYGPDRVVGFSPIPAMSMVSYAAGSRYLSLIGGTSLSF
                     YDWYCDLPPSSPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTESRYNG
                     TKTIAVTPDFSEVAKLSDEWMSPTQGTDAALAMTMGHVILKEYHLTNKSKYFTNYIKQ
                     YTDMPFLVILEEKKEVFVPGRTLRASDIHDTLGEKDNTEWKPLLIDQNTNEIVVPTGT
                     IGFRWDGSGKWNIENKNAMNDADIDPKITLKDNNDEIISVGFPYFNNKVHDQEIFTNT
                     THDSILMRNVPIRQLTLVNGKEVKVSTVFDLMMANYSVDQGLGGDNVAASFNDDVPYT
                     PAWNEKVTGVPREQTVRIAREFSENADKTQGKSMVILGAAINHWYHMDMIYRGIINML
                     MMCGCIGKSGGGWSHYVGQEKLRPQTGWLPLAFGLDWHRPPRQMNGTSFFYNHSSQWR
                     YEKLEVDEILSPLIDKTKWKNYSIIDCNVRSEKMGWLPSAPQFEDNPLEITKQAEEAG
                     INVKDYIVKKLKSKDLKFSCEDPDNPKNFPHNMFIWRSNILGSSGKGHEYLLKYLLGA
                     QNAVLGNETDKKPSEVKWREGVEGKVDLFVTLDFRMSTTCLYSDIVLPSATWYEKNDL
                     NTSDMHPFIHPLSKAVDPAWESRSDWEIYKGLAKKFSELCPGHLGKEKDIVALPILHD
                     TSAEMAQATDVKAWFDGECEAIPGKTMPNFIEVERNYPDTYKKFTSLGPLMSKMGNGG
                     KGIEWDTKDEVTSLGDLNKIVKEEGVSKGLPKIETDIDATEVILSLAPETNGKVAVKA
                     WKSLGKITGKDHTHLAKSKEDEQIRYRDIQAQPRKIISSPIWSGLEDEHVSYNAGYIN
                     VHEYIPWRTLTGRQQFYQDHKWMIDFGENLCTYKPPINTRTVEPIINENNDGRSQVVL
                     NWITPHQKWGIHSTYSDNLLMLTLNRGGPVVWISEVDAQKINVEDNDWIELYNSNGTI
                     AARAVVSQRVPEGMSLMYHAQEKITTTPIAEKSGFRGGIHNSVTRTITKPTHMIGGYA
                     QLSYGFNYYGTVGSNRDEFVIVRKMNKVDWKDEPAKKNN"
     misc_feature    complement(672685..676386)
                     /gene="narG"
                     /locus_tag="COSY_0649"
                     /note="Nitrate reductase alpha subunit [Energy production
                     and conversion]; Region: NarG; COG5013"
                     /db_xref="CDD:227346"
     misc_feature    complement(<675340..676257)
                     /gene="narG"
                     /locus_tag="COSY_0649"
                     /note="Respiratory nitrate reductase A (NarGHI), alpha
                     chain (NarG) and related proteins. Under anaerobic
                     conditions in the presence of nitrate, E. coli synthesizes
                     the cytoplasmic membrane-bound quinol-nitrate
                     oxidoreductase (NarGHI), which reduces nitrate to...;
                     Region: MopB_Nitrate-R-NarG-like; cd02750"
                     /db_xref="CDD:239151"
     misc_feature    complement(order(676105..676107,676204..676206,
                     676210..676212,676222..676224,676234..676236))
                     /gene="narG"
                     /locus_tag="COSY_0649"
                     /note="[4Fe-4S] binding site [ion binding]; other site"
                     /db_xref="CDD:239151"
     misc_feature    complement(<674626..>674877)
                     /gene="narG"
                     /locus_tag="COSY_0649"
                     /note="Molybdopterin-Binding (MopB) domain of the MopB
                     superfamily of proteins, a  large, diverse, heterogeneous
                     superfamily of enzymes that, in general, bind
                     molybdopterin as a cofactor. The MopB domain is found in a
                     wide variety of molybdenum- and...; Region:
                     Molybdopterin-Binding; cl09928"
                     /db_xref="CDD:245203"
     misc_feature    complement(673885..>674253)
                     /gene="narG"
                     /locus_tag="COSY_0649"
                     /note="Molybdopterin-Binding (MopB) domain of the MopB
                     superfamily of proteins, a  large, diverse, heterogeneous
                     superfamily of enzymes that, in general, bind
                     molybdopterin as a cofactor. The MopB domain is found in a
                     wide variety of molybdenum- and...; Region:
                     Molybdopterin-Binding; cl09928"
                     /db_xref="CDD:245203"
     misc_feature    complement(673192..>673284)
                     /gene="narG"
                     /locus_tag="COSY_0649"
                     /note="Molybdopterin-Binding (MopB) domain of the MopB
                     superfamily of proteins, a  large, diverse, heterogeneous
                     superfamily of enzymes that, in general, bind
                     molybdopterin as a cofactor. The MopB domain is found in a
                     wide variety of molybdenum- and...; Region:
                     Molybdopterin-Binding; cl09928"
                     /db_xref="CDD:245203"
     misc_feature    complement(672706..673128)
                     /gene="narG"
                     /locus_tag="COSY_0649"
                     /note="Respiratory nitrate reductase A (NarGHI), alpha
                     chain (NarG) and related proteins. Under anaerobic
                     conditions in the presence of nitrate, E. coli synthesizes
                     the cytoplasmic membrane-bound quinol-nitrate
                     oxidoreductase (NarGHI), which reduces nitrate to...;
                     Region: MopB_CT_Nitrate-R-NarG-like; cd02776"
                     /db_xref="CDD:239177"
     misc_feature    complement(order(672727..672732,672826..672828,
                     672892..672894,673081..673095,673102..673113))
                     /gene="narG"
                     /locus_tag="COSY_0649"
                     /note="molybdopterin cofactor binding site; other site"
                     /db_xref="CDD:239177"
     gene            677171..677701
                     /gene="moaB"
                     /locus_tag="COSY_0650"
                     /db_xref="GeneID:5171989"
     CDS             677171..677701
                     /gene="moaB"
                     /locus_tag="COSY_0650"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="YP_001219487.1"
                     /db_xref="GI:148244793"
                     /db_xref="GeneID:5171989"
                     /translation="MRKINIKIGFITISDRAARGEYEDISGPAMQNWIKNAVLSPYTV
                     EDITIEDNQLLIEKTMIDFADNKHCNLILTTGGTGVTTRDVTPEATHIVCERIFDGFA
                     QQMRNISLRTVPTAILSRQTAGTRGSSLIINLPGKPAAIAICLGAVFLAVPKCLELLD
                     QSNIQIDLDFIEQNLE"
     misc_feature    677186..677647
                     /gene="moaB"
                     /locus_tag="COSY_0650"
                     /note="MogA_MoaB family. Members of this family are
                     involved in biosynthesis of the molybdenum cofactor (MoCF)
                     an essential cofactor of a diverse group of redox enzymes.
                     MoCF biosynthesis is an evolutionarily conserved pathway
                     present in eubacteria, archaea; Region: MogA_MoaB;
                     cd00886"
                     /db_xref="CDD:238451"
     misc_feature    order(677399..677407,677495..677497,677573..677578,
                     677588..677590,677597..677599)
                     /gene="moaB"
                     /locus_tag="COSY_0650"
                     /note="MPT binding site; other site"
                     /db_xref="CDD:238451"
     misc_feature    order(677405..677407,677411..677416,677420..677422,
                     677432..677434,677456..677464,677477..677479,
                     677486..677491,677519..677521,677528..677530,
                     677645..677647)
                     /gene="moaB"
                     /locus_tag="COSY_0650"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238451"
     gene            complement(678095..680341)
                     /gene="cbbO"
                     /locus_tag="COSY_0651"
                     /db_xref="GeneID:5172071"
     CDS             complement(678095..680341)
                     /gene="cbbO"
                     /locus_tag="COSY_0651"
                     /note="Similar to nitric-oxide reductase activation NorD
                     protein / von Willebrand factor type A domain protein."
                     /codon_start=1
                     /transl_table=11
                     /product="Rubisco regulator CbbO"
                     /protein_id="YP_001219488.1"
                     /db_xref="GI:148244794"
                     /db_xref="GeneID:5172071"
                     /translation="MPEVSQYKPLNCAFNTIQGVFVENIEQAAKRLSEQGLIEYYKGA
                     ELLAKIGQGDTLSIVFLKTMPWIGEFYGDGSIQKIVDFAYQKISRTPNKDAVKPFLNS
                     FIDVIEHTNNDQLDEYLNLIEYHLNKTTFSIHGIHDTHASPSLLSMLANMRLLLEQLE
                     FEGIYKWINYGLRYFQDHPKRQEEYFSLLSADSKAVFQRQRKGLLFIDVERKINLFQR
                     ALWKTEFMYAPYSPDFEKLEHFRPYLEDNIIRLPDIYELFNGVNACKRYMALMAHLIA
                     HHQFTTKIIADNVSPQQRFFTEIFEDARVEYLAMQEYPGLKNLWLNLIPIVDEFDCDD
                     KYQSCLRHRAIMLTYALLDDNHHYKNKILLDYVEKFKTLMNTGKTSTSDSLNLGLKYL
                     IKTRSASDALANMYFENTEVTYRDDNRSMWLFIEKFDEEDNIFEHQKKSEEEDEDQVE
                     VIPPHYYDEWDYSYETYKPDWVAVYERLHSHSDASKIDRILDKHSALVKQLKKVLDLL
                     KPQNKKRLRYQEEGAELDLDIALRSVIDIKNGSQPDTRINVDFEHDSRSVSVLLLLDL
                     SESLNKVVGKFGQTILELSQEAVSLLAWAVEQLGDNFSISGFNSNTRQKVMYYHIKGY
                     GEHWDDTVKARLADLRAEFSTRMGAAIRHGAHYLDLQQSDKKLMLVLTDGEPADIDIY
                     DPKTLIQDAHKAVQEVQQKGIYPYCISLDKKADEYIVDIFGSHYSVIDRIESLPQELP
                     KLFLSLTK"
     misc_feature    complement(678155..678601)
                     /gene="cbbO"
                     /locus_tag="COSY_0651"
                     /note="norD type: Denitrifying bacteria contain both
                     membrane bound and periplasmic nitrate reductases.
                     Denitrification plays a major role  in completing the
                     nitrogen cycle by converting nitrate or nitrite to
                     nitrogen gas. The pathway for microbial...; Region:
                     vWA_norD_type; cd01454"
                     /db_xref="CDD:238731"
     gene            complement(680357..681166)
                     /gene="cbbQ"
                     /locus_tag="COSY_0652"
                     /db_xref="GeneID:5171846"
     CDS             complement(680357..681166)
                     /gene="cbbQ"
                     /locus_tag="COSY_0652"
                     /note="Similar to nitric-oxide reductase NorQ protein.
                     ATPase, AAA family."
                     /codon_start=1
                     /transl_table=11
                     /product="Rubisco regulator CbbQ"
                     /protein_id="YP_001219489.1"
                     /db_xref="GI:148244795"
                     /db_xref="GeneID:5171846"
                     /translation="MSNFDINQFKIILEPFYKAQSTEVELYTAAYNLGLPVMIKGPTG
                     CGKSRFIEYMAYKLDKPIITVSCNEDITASDLIGRFLLDTNGTRWVDGPLTLAARHGA
                     ICYLDEIVEARQDTMVVIHSLTDHRRELMLDKKGELVKAHSDFQLVISYNPAYQSLMK
                     DLKQSTKQRFTGMDFDYVSAELETSIVVRESGVGGDIATKLVKLAQVTRNLVGHGIDE
                     GASTRLLNYAGTLIASGVGVKDACNMALVCPITDDVEIRTTMGSAIDAIFD"
     misc_feature    complement(680363..681073)
                     /gene="cbbQ"
                     /locus_tag="COSY_0652"
                     /note="gas vesicle protein GvpN; Region: gas_vesic_GvpN;
                     TIGR02640"
                     /db_xref="CDD:131688"
     misc_feature    complement(680657..681061)
                     /gene="cbbQ"
                     /locus_tag="COSY_0652"
                     /note="AAA domain (dynein-related subfamily); Region:
                     AAA_5; pfam07728"
                     /db_xref="CDD:219538"
     misc_feature    complement(681023..681046)
                     /gene="cbbQ"
                     /locus_tag="COSY_0652"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(680714..680716,680846..680848,
                     681023..681043))
                     /gene="cbbQ"
                     /locus_tag="COSY_0652"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(680843..680860)
                     /gene="cbbQ"
                     /locus_tag="COSY_0652"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(680363..680620)
                     /gene="cbbQ"
                     /locus_tag="COSY_0652"
                     /note="CbbQ/NirQ/NorQ C-terminal; Region: CbbQ_C;
                     pfam08406"
                     /db_xref="CDD:149460"
     gene            complement(681254..682636)
                     /gene="cbbM"
                     /locus_tag="COSY_0653"
                     /db_xref="GeneID:5171911"
     CDS             complement(681254..682636)
                     /gene="cbbM"
                     /locus_tag="COSY_0653"
                     /EC_number="4.1.1.39"
                     /note="catalyzes the carboxylation of D-ribulose
                     1,5-bisphosphate in carbon dioxide fixation"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose bisphosphate carboxylase"
                     /protein_id="YP_001219490.1"
                     /db_xref="GI:148244796"
                     /db_xref="GeneID:5171911"
                     /translation="MDQSNRYADLSLDEDTLLAEGGHILVAYTMNIMPNFGGYLETAA
                     HFAAESSTGTNVEVSTTDDFTKDLDAMVYEIDEVKGIMKIAYPCGLFDRNLIDGRAMV
                     VSFLTLAIGNNQGMGDVKCAQMIDFHVPKQMLDIFDGPSVDITDLWNLLGRDRKNGGY
                     IAGTIIKPKLGLRPQPFAEAAYQFWLGGDFIKNDEPQGNQVYARMKDVMPLVSDAMKR
                     AQDETGEAKIFSANITADDYHEMIARGEYILEAFGENAHHVAFLVDGYVGGCGMVTTA
                     RRNFPGQYLHYHRAGHGAITSPSSVRGYTALVLAKLSRLMGASGIHVGTMGYGKMEGG
                     ADDRNIAYMIERDSADGPVYHQEWFGMKPTTPIISGGMNALRLPGFFENLGHGNVINT
                     SGGGSYGHIDSPSAGAKSLRQAYDCWMAKADPIEFARDNNEFARAFESFPGDADSLYP
                     GWRDKLGVHK"
     misc_feature    complement(681305..682636)
                     /gene="cbbM"
                     /locus_tag="COSY_0653"
                     /note="ribulose bisphosphate carboxylase; Provisional;
                     Region: PRK13475"
                     /db_xref="CDD:184072"
     misc_feature    complement(681314..682633)
                     /gene="cbbM"
                     /locus_tag="COSY_0653"
                     /note="Ribulose bisphosphate carboxylase large chain, Form
                     II; Region: RuBisCO_large_II; cd08211"
                     /db_xref="CDD:173976"
     misc_feature    complement(order(681731..681733,681746..681748,
                     681755..681769,681803..681805,681812..681817,
                     681821..681832,681845..681847,681905..681910,
                     681917..681925,681929..681934,682019..682024,
                     682031..682045,682052..682054,682127..682138,
                     682301..682306,682313..682321,682328..682330,
                     682433..682435,682475..682477,682481..682492))
                     /gene="cbbM"
                     /locus_tag="COSY_0653"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:173976"
     misc_feature    complement(order(681455..681463,681527..681532,
                     681536..681538,681665..681667,681671..681673,
                     681770..681772,682052..682057,682142..682144,
                     682301..682303))
                     /gene="cbbM"
                     /locus_tag="COSY_0653"
                     /note="active site"
                     /db_xref="CDD:173976"
     misc_feature    complement(682061..682063)
                     /gene="cbbM"
                     /locus_tag="COSY_0653"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:173976"
     misc_feature    complement(682052..682057)
                     /gene="cbbM"
                     /locus_tag="COSY_0653"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:173976"
     gene            682738..683028
                     /locus_tag="COSY_0654"
                     /pseudo
                     /db_xref="GeneID:5171816"
     misc_feature    682738..683028
                     /locus_tag="COSY_0654"
                     /note="Probable gene remnant. Similar to the N-terminal
                     region of Rubisco operon transcriptional regulator
                     TR:Q6SEU6 (292 aa)."
                     /pseudo
     gene            complement(683624..684841)
                     /gene="argJ"
                     /locus_tag="COSY_0655"
                     /db_xref="GeneID:5172672"
     CDS             complement(683624..684841)
                     /gene="argJ"
                     /locus_tag="COSY_0655"
                     /EC_number="2.3.1.1"
                     /note="bifunctional amino-acid N-acetyltransferase /
                     glutamate N-acetyltransferase."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional arginine biosynthesis protein ArgJ"
                     /protein_id="YP_001219491.1"
                     /db_xref="GI:148244797"
                     /db_xref="GeneID:5172672"
                     /translation="MDNILNINGITCAAINSGIKHAQNFSENLSIKDTKKLDLSIIFL
                     KKGTQTAAVFTKNIFCAAPVLVAKNHLNHAIKALVINSGNANAGTGLVGLKNTYKVCD
                     LVAKELDIKAEQVLPFSTGVIGQLLPMACFENNISTLVSNLAIDNFSQVAQAIMTTDL
                     VDKVYSKQFKIGDNLITITGFAKGSGMIRPDMATMLSFIFTDIEATQSELQNCLTQAV
                     NQSFNRITIDGDTSTNDACTLSATGVSSIKINDCMEKFQQSLNTVTKILAHKIIKDGE
                     GATKFVEVCVKGGISVKDCLEVAYTVAHSPLVKTALFASDANWGRILAAVGRANIKYL
                     RIEDVSIYLGKICLIKAGELNVYYTEAQGEAQMKKSEIVITIEIGKGELTESVWTTDL
                     SYDYIKINSAYRT"
     misc_feature    complement(683627..684823)
                     /gene="argJ"
                     /locus_tag="COSY_0655"
                     /note="Ornithine acetyltransferase (OAT) family; also
                     referred to as ArgJ. OAT catalyzes the first and fifth
                     steps in arginine biosynthesis, coupling acetylation of
                     glutamate with deacetylation of N-acetylornithine, which
                     allows recycling of the acetyl group in...; Region: OAT;
                     cd02152"
                     /db_xref="CDD:239065"
     misc_feature    complement(order(683660..683668,683795..683797,
                     683852..683863,683870..683875,683879..683890,
                     683894..683896,683900..683905,683909..683914,
                     683921..683929,684149..684160,684269..684271,
                     684281..684283,684470..684475,684578..684580,
                     684662..684676))
                     /gene="argJ"
                     /locus_tag="COSY_0655"
                     /note="heterotetramer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239065"
     misc_feature    complement(order(683627..683632,683642..683644,
                     684260..684262,684284..684286,684293..684295,
                     684368..684373,684479..684484))
                     /gene="argJ"
                     /locus_tag="COSY_0655"
                     /note="active site pocket [active]"
                     /db_xref="CDD:239065"
     misc_feature    complement(684260..684265)
                     /gene="argJ"
                     /locus_tag="COSY_0655"
                     /note="cleavage site"
                     /db_xref="CDD:239065"
     gene            complement(684950..686545)
                     /locus_tag="COSY_0656"
                     /db_xref="GeneID:5172163"
     CDS             complement(684950..686545)
                     /locus_tag="COSY_0656"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="YP_001219492.1"
                     /db_xref="GI:148244798"
                     /db_xref="GeneID:5172163"
                     /translation="MEKNCLKSKVWISVLALLVAMPIFVVAVSWFFPERELWAHFSTI
                     LLPNLISATVVLLIGVGVGVTFLGTILAYLVVMVEFPGRQWLEWALFLPFAVPAYVLA
                     FVYLGVFDYSGYVQVWMREVLGLSGFDIRAGSWAIILTFVLVFYPYVYMMARASFKRQ
                     KVNIIEAGRLLGTSPLRTFFKISLPLARPAAAAGLLVTLMEILADFGVVSLFNFDTFT
                     TAIYSAWGDFRSIEVAAQLASLLVLVAFFLIYFEKKARGQAKYYSSDVVNKKPYRAFG
                     IMGWLISIFIFSVFMLAFAMPMLQLIIWGWAYSSKELNVRYTDLIISTLVLTVSATLI
                     TVSIATILALPNHCKKNSSWLKSVINIATLGYALPGSIMAVGLLYGINQVSAVSIYFG
                     GQSINQIIFGSIALLLFSYISRFMAIGYNSIKASAEQIKPMFTQSARLLGVSRLRLIW
                     QIYLPMMTPGILAGGLLVAVDVMKELPATYLLRPFGWDTLAIQVYELSAEGLFERAAI
                     PALIMVLFGSVLMIIFQYLDKKS"
     misc_feature    complement(684953..686524)
                     /locus_tag="COSY_0656"
                     /note="ABC-type Fe3+ transport system, permease component
                     [Inorganic ion transport and metabolism]; Region: ThiP;
                     COG1178"
                     /db_xref="CDD:224099"
     misc_feature    complement(685871..686332)
                     /locus_tag="COSY_0656"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(685871..685876,685913..685918,
                     685925..685936,685955..685957,685964..685969,
                     686009..686011,686060..686062,686069..686074,
                     686084..686086,686090..686095,686102..686104,
                     686111..686113,686117..686122,686228..686230,
                     686234..686239,686246..686275,686279..686290,
                     686318..686320))
                     /locus_tag="COSY_0656"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(685919..685936,686228..686272))
                     /locus_tag="COSY_0656"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(685871..685873,685880..685882,
                     685916..685918,686135..686137,686228..686230))
                     /locus_tag="COSY_0656"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(685988..685990,686000..686005,
                     686021..686059))
                     /locus_tag="COSY_0656"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(684995..685585)
                     /locus_tag="COSY_0656"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(684995..684997,685004..685009,
                     685016..685021,685025..685030,685037..685042,
                     685070..685075,685103..685108,685115..685126,
                     685145..685147,685154..685159,685199..685201,
                     685250..685252,685259..685264,685283..685285,
                     685289..685294,685301..685303,685307..685309,
                     685313..685318,685412..685414,685418..685423,
                     685430..685459,685463..685474,685505..685507,
                     685520..685525,685532..685537))
                     /locus_tag="COSY_0656"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(685109..685126,685412..685456))
                     /locus_tag="COSY_0656"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(685040..685042,685070..685072,
                     685079..685081,685106..685108,685331..685333,
                     685412..685414))
                     /locus_tag="COSY_0656"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(685178..685180,685190..685195,
                     685211..685249))
                     /locus_tag="COSY_0656"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(686627..687646)
                     /locus_tag="COSY_0657"
                     /db_xref="GeneID:5172696"
     CDS             complement(686627..687646)
                     /locus_tag="COSY_0657"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter substrate-binding protein"
                     /protein_id="YP_001219493.1"
                     /db_xref="GI:148244799"
                     /db_xref="GeneID:5172696"
                     /translation="MNIKIRIVPALIVLLLVVTSVGIARARSEDLVTVYSSRKEHLIK
                     PLFESFTRDTGIQVTYLTGKGGALIERLKLEGKNTNADMFMTVDAGNLWYAATQDLFQ
                     AVQTQTLENNIPSHLRDSKGLWTGLSVRARTIVYSTERVNPVDLSTYENLADTKWAGR
                     LCLRTSKKIYTKSLVASMIYHHGINKASDIISGWVNNLAATPNAKDSHIMNAIISGQC
                     DIGLVNTYYFARLITKNPNVPLKLFWANQDTTGVHVNISGAGVTKYATNVKGAIKLLE
                     WLSNAKAQAIYASLNKEYPANQNVISDEVVSSWGSFKQDKMNLEQTGILQADAVKLMQ
                     TKGYR"
     misc_feature    complement(686645..687511)
                     /locus_tag="COSY_0657"
                     /note="ABC-type Fe3+ transport system, periplasmic
                     component [Inorganic ion transport and metabolism];
                     Region: AfuA; COG1840"
                     /db_xref="CDD:224753"
     misc_feature    complement(686723..687511)
                     /locus_tag="COSY_0657"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_8; pfam13416"
                     /db_xref="CDD:222114"
     gene            complement(687702..688352)
                     /locus_tag="COSY_0658"
                     /db_xref="GeneID:5172565"
     CDS             complement(687702..688352)
                     /locus_tag="COSY_0658"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein"
                     /protein_id="YP_001219494.1"
                     /db_xref="GI:148244800"
                     /db_xref="GeneID:5172565"
                     /translation="MLLVNHLSISYQATQILNDFDLSLATGDIFALLGDSGSGKSSVL
                     RFISGLDEAQSGQVILNGKQLSNNGTHNVPPELREIGMVFQDYALFPHMNVKKNISFG
                     IYNLSNSKQKTKVEELLLMIGLKGVERKYPHQLSGGEQQRVALARALAPSPKLLLLDE
                     PFSSLDKNHQEQLVLQVRDILKKTNITSILVTHDKYEATIFADKVGVIKNKKLTIN"
     misc_feature    complement(687705..688352)
                     /locus_tag="COSY_0658"
                     /note="ABC-type antimicrobial peptide transport system,
                     ATPase component [Defense mechanisms]; Region: SalX;
                     COG1136"
                     /db_xref="CDD:224059"
     misc_feature    complement(687714..688349)
                     /locus_tag="COSY_0658"
                     /note="ATP-binding cassette domain of the carbohydrate and
                     solute transporters-like; Region: ABC_Carb_Solutes_like;
                     cd03259"
                     /db_xref="CDD:213226"
     misc_feature    complement(688230..688253)
                     /locus_tag="COSY_0658"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213226"
     misc_feature    complement(order(687774..687776,687873..687878,
                     688098..688100,688227..688235,688239..688244))
                     /locus_tag="COSY_0658"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213226"
     misc_feature    complement(688098..688109)
                     /locus_tag="COSY_0658"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213226"
     misc_feature    complement(687921..687950)
                     /locus_tag="COSY_0658"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213226"
     misc_feature    complement(687873..687890)
                     /locus_tag="COSY_0658"
                     /note="Walker B; other site"
                     /db_xref="CDD:213226"
     misc_feature    complement(687855..687866)
                     /locus_tag="COSY_0658"
                     /note="D-loop; other site"
                     /db_xref="CDD:213226"
     misc_feature    complement(687768..687788)
                     /locus_tag="COSY_0658"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213226"
     gene            complement(688419..690113)
                     /locus_tag="COSY_0659"
                     /db_xref="GeneID:5172530"
     CDS             complement(688419..690113)
                     /locus_tag="COSY_0659"
                     /EC_number="1.3.3.5"
                     /note="bilirubin oxidase"
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase"
                     /protein_id="YP_001219495.1"
                     /db_xref="GI:148244801"
                     /db_xref="GeneID:5172530"
                     /translation="MKRRDFIKTSILSSSILVVGCSDKRSDKFIYPDYADRSFIVPPL
                     IEPTIVNGKRIFKFSINHNTIEIFKGKLTCVLGYGDSILGPTIRVDNMDNVGFEITNY
                     LSVNTTVHFHGLHLPAKEDGGPYQIIPPNKTWKPSWRINQLASTQWYHPHLEGYTGEQ
                     VYKGMAGFFLIDDETSRLLDIPKTYGVDDLPVVIQDRRFDEKAQLLYLNKGDFDKSGG
                     MKGYTILVNGKPVPILNVPAQVIRLRILNGSNARIYNLGFEGDIQFYQIASDGGFLEK
                     PVSLTRVLLGPAERVEILLDLNNSKNTILRFKSFSAEYYDKQKLNGHQFGGPFKVGGT
                     GRLSDSVDTLDKINFDVMSIYVNKSTSTNVVRKIPNKLTKIVRLKESDAIKTRNFGLT
                     VMSGFKINRRVFTSMFKVINGIVLEGEHMLHLINGVQMDMNVINEVVKKGDVEIWRIT
                     NGAHTTHPFHIHDIQFQILDREQGDGSDPTLPNENERGWKDTVLLMPEETVRVVAKFD
                     HYADTQYPYMYHCHILEHEDAGMMGQFLVVEPEDFDTVMTDIDNNKRIPLRSFCEI"
     misc_feature    complement(688500..690113)
                     /locus_tag="COSY_0659"
                     /note="multicopper oxidase; Provisional; Region: PRK10965"
                     /db_xref="CDD:236810"
     misc_feature    complement(689586..689915)
                     /locus_tag="COSY_0659"
                     /note="Multicopper oxidase; Region: Cu-oxidase_3;
                     pfam07732"
                     /db_xref="CDD:219542"
     misc_feature    complement(<689214..>689447)
                     /locus_tag="COSY_0659"
                     /note="Multicopper oxidase; Region: Cu-oxidase; pfam00394"
                     /db_xref="CDD:215896"
     misc_feature    complement(688491..688853)
                     /locus_tag="COSY_0659"
                     /note="Multicopper oxidase; Region: Cu-oxidase_2;
                     pfam07731"
                     /db_xref="CDD:219541"
     gene            complement(690174..691082)
                     /locus_tag="COSY_0660"
                     /db_xref="GeneID:5171993"
     CDS             complement(690174..691082)
                     /locus_tag="COSY_0660"
                     /note="Similar to sterol desaturase."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219496.1"
                     /db_xref="GI:148244802"
                     /db_xref="GeneID:5171993"
                     /translation="MLMEINPFEYLMDPHRRIYWLFLLSSLMITFVFLKFHPKQQRIV
                     LSKKLWLHPSSLLDYSYFIFSVFFRVMIILPVIISTKEVALFVNIVLLNQYGFVRIET
                     LSYTQVMVLFTLILFILNDFTRYWLHRLLHFVPWLWVFHKVHHSAKVLNPLTFYRVHP
                     IEFLLFGFRYSLSIGFVTGVFVFLFGSLVSIYDILGVNLFVFIFSLLGSNLRHSHIKL
                     GFGNVVELFLISPLQHQIHHSKNYMNTNFGGFLSVWDYLFGTLILSKNVTNIKFGLEK
                     TQMKNFQSLKDLLFFPFIVTYKQIKK"
     misc_feature    complement(690225..691031)
                     /locus_tag="COSY_0660"
                     /note="Sterol desaturase [Lipid metabolism]; Region: ERG3;
                     COG3000"
                     /db_xref="CDD:225546"
     misc_feature    complement(690366..690746)
                     /locus_tag="COSY_0660"
                     /note="Fatty acid hydroxylase superfamily; Region:
                     FA_hydroxylase; pfam04116"
                     /db_xref="CDD:217907"
     gene            complement(691066..692031)
                     /locus_tag="COSY_0661"
                     /db_xref="GeneID:5172711"
     CDS             complement(691066..692031)
                     /locus_tag="COSY_0661"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219497.1"
                     /db_xref="GI:148244803"
                     /db_xref="GeneID:5172711"
                     /translation="MMRYLVVIIFFISIVVNAVGEKFFNQVIIVNIILAIKSVDLLID
                     NINQANSTRIRMQFGNLVSSWKKVETTYFLGDLNEDYLDTPRYIDIFHGNNEEIKPQL
                     DLIINSNDELFNAMYKYSHKTINALEYVLFTKDLSHQRVKNMALIIAKSIKSYLSEIL
                     DGYKMYQSKFLENEQYASAILLNTLIAGTYKLKEWRVGDVAGLSKKFKNKPNNYRAEY
                     ATSGNSVNAIKAILETQAQIINSPDYQDLGDISRQFKARKEIDQAISALNDSIANANN
                     MSEFDFINDKGKRLYQSTNRLMKAYYISLMDKLGFVSKVLDADGD"
     misc_feature    complement(691132..691923)
                     /locus_tag="COSY_0661"
                     /note="Imelysin; Region: Peptidase_M75; pfam09375"
                     /db_xref="CDD:220211"
     gene            complement(692038..693405)
                     /locus_tag="COSY_0662"
                     /db_xref="GeneID:5172547"
     CDS             complement(692038..693405)
                     /locus_tag="COSY_0662"
                     /note="Similar to thiol oxidoreductase."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219498.1"
                     /db_xref="GI:148244804"
                     /db_xref="GeneID:5172547"
                     /translation="MLRKLNYKYSAALIILILVISLMERVFANDFSNLSTYELSQSFT
                     QVQPNLSNDKLDKFILGKSFFRIPWVEAPSSTTARDGLGPLFSANTCVNCHVKNGRGK
                     VFEVNNIVDKSHVIRLSIPLNDTDEHQGMIAKFGSIPEPNYGVQISINGVPGVPFEAK
                     SLVHYSTKNIHYSDNTIIILQQPIVKLEKLGYGDLLPNTIISARIAPALVGLGLLEQI
                     TDEQILANEDINDANHDGISGKANRVWSEQTKKIEIGRYAWKASAPTVKYQSANAAVN
                     DMGLTNPIYEHQSCTLIQVECINSSKDGEKHELTAQRLNAISYYLTHLKLPKSIISQY
                     QGQRLFSEIGCSKCHVPSYSLPNITIYPYSDFLLHDMGKDLADDRSEFDALGNEWRTP
                     PLWRLGRVSLILKDNKNFLHDGRARNLEQAIIWHGGEAERSKTLFMNLPVSSRGKILQ
                     FLNEI"
     misc_feature    complement(692050..693303)
                     /locus_tag="COSY_0662"
                     /note="Protein of unknown function (DUF1111); Region:
                     DUF1111; pfam06537"
                     /db_xref="CDD:219077"
     misc_feature    complement(692041..693282)
                     /locus_tag="COSY_0662"
                     /note="Predicted thiol oxidoreductase [Energy production
                     and conversion]; Region: COG3488"
                     /db_xref="CDD:226019"
     gene            complement(693383..694693)
                     /locus_tag="COSY_0663"
                     /db_xref="GeneID:5172568"
     CDS             complement(693383..694693)
                     /locus_tag="COSY_0663"
                     /note="Similar to iron-regulated protein A."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219499.1"
                     /db_xref="GI:148244805"
                     /db_xref="GeneID:5172568"
                     /translation="MHDSTKKLMISFVLTVVIVISAASVFLSGNEINPLLITYANIAT
                     INYTDALNDAKKLGIKLKDFTINPTIETMGNAKAAWLNARESYSQTEAFRLSNGPIDA
                     EEGWHTSYGAPEGRLNAWPLDENMIDYTTNAKGRKTSGNIIDTPDIFNPGGENPLVID
                     VSIITSDVLVALNENGGNANVTTGYHVIEFLLWGQDQDYTNFIKDSVTHGALLAGQRP
                     LADYTINVNADRRKQYLNAAASLIISDLESITSAWADGDSTNYKAALLGQNSDVTKNI
                     NVKVALKQIFSGLGIFIKSELANERIAMAVLTPSEEDEHSCFSDNTHRDITQNFQGFK
                     NLLFGTYNGFDYGVALIDAMKDKTKLMGLIASVNTKINQMNTLAQVSRHFDYQIHPND
                     SQARQIKILKNELRAIGDQMIYVAKSNGIDLTVGNIMDVEEIKL"
     misc_feature    complement(693500..694582)
                     /locus_tag="COSY_0663"
                     /note="Imelysin; Region: Peptidase_M75; cl09159"
                     /db_xref="CDD:245024"
     gene            695502..696641
                     /locus_tag="COSY_0664"
                     /db_xref="GeneID:5172121"
     CDS             695502..696641
                     /locus_tag="COSY_0664"
                     /note="Co/Zn/Cd cation transporter, cation diffusion
                     facilitator (CDF) family"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-efflux family protein"
                     /protein_id="YP_001219500.1"
                     /db_xref="GI:148244806"
                     /db_xref="GeneID:5172121"
                     /translation="MDLNKRTQASQKVTLVGITVDFLLAILKVITGSIGNSGALIADG
                     AHSFSDLLSDGLVLYATKHSTLDADEEHPYGHNRFETVAILGLAIILTIVGLGIILDA
                     MIKLSNPITLSHSTLLLNITILSIFSKEALYWYTLKVANDYKSDLLKANAWHHRSDAL
                     SSIVVLIGILGSLNDYPYLDSIAAIVVGVMIIYIAWKLGLNATKELVDTSIDAQQVAE
                     LKHALGQINDVNSVHSLRTRKIGHTISCDVHIQVDPFLSVSEGHIISISVERVAKKCL
                     KNLNDVTVHIDVEDDETNSPYKALPERSEALGILTKALFNNKYSSEISRIQLHYLESK
                     IHVDFYLPLKCLQTDNTADKILTKLQETVNNLDNFGKIKVYFSQN"
     misc_feature    695502..696395
                     /locus_tag="COSY_0664"
                     /note="Predicted Co/Zn/Cd cation transporters [Inorganic
                     ion transport and metabolism]; Region: MMT1; COG0053"
                     /db_xref="CDD:223131"
     misc_feature    695568..696362
                     /locus_tag="COSY_0664"
                     /note="cation diffusion facilitator family transporter;
                     Region: CDF; TIGR01297"
                     /db_xref="CDD:233348"
     gene            696989..697348
                     /locus_tag="COSY_0665"
                     /db_xref="GeneID:5172524"
     CDS             696989..697348
                     /locus_tag="COSY_0665"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="YP_001219501.1"
                     /db_xref="GI:148244807"
                     /db_xref="GeneID:5172524"
                     /translation="MAVLELNLSNFDETIQSNDIVILDFWAPWCGPCKQFAPIYDEVS
                     NKVDNVIFAKINTEDEQKLASNFQIRSIPTLMIFREQIEVFSQPGAMSGSNLEDVITK
                     AKAFDMNEMRKEIKKKK"
     misc_feature    697013..697288
                     /locus_tag="COSY_0665"
                     /note="TRX family; composed of two groups: Group I, which
                     includes proteins that exclusively encode a TRX domain;
                     and Group II, which are composed of fusion proteins of TRX
                     and additional domains. Group I TRX is a small ancient
                     protein that alter the redox...; Region: TRX_family;
                     cd02947"
                     /db_xref="CDD:239245"
     misc_feature    697040..697219
                     /locus_tag="COSY_0665"
                     /note="Thioredoxin-like; Region: Thioredoxin_8; pfam13905"
                     /db_xref="CDD:222448"
     misc_feature    order(697076..697078,697085..697087)
                     /locus_tag="COSY_0665"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239245"
     gene            complement(697355..697681)
                     /locus_tag="COSY_0666"
                     /db_xref="GeneID:5172612"
     CDS             complement(697355..697681)
                     /locus_tag="COSY_0666"
                     /EC_number="1.20.4.1"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="YP_001219502.1"
                     /db_xref="GI:148244808"
                     /db_xref="GeneID:5172612"
                     /translation="MIKMYGIKNCDTIKKAKKFFINHQVDFEFIDFRDNPIDKTKLQT
                     FVDKVTWENLINKRSTTYRNLNDEEKGNITLDLVLKNPTLIKRPILIIGDDIMVGFSE
                     KNYLKL"
     misc_feature    complement(697376..697678)
                     /locus_tag="COSY_0666"
                     /note="Arsenate Reductase (ArsC) family, Yffb subfamily;
                     Yffb is an uncharacterized bacterial protein encoded by
                     the yffb gene, related to the thioredoxin-fold arsenic
                     reductases, ArsC. The structure of Yffb and the
                     conservation of the catalytic cysteine...; Region:
                     ArsC_Yffb; cd03035"
                     /db_xref="CDD:239333"
     misc_feature    complement(697358..697669)
                     /locus_tag="COSY_0666"
                     /note="ArsC family; Region: ArsC; pfam03960"
                     /db_xref="CDD:202832"
     misc_feature    complement(order(697382..697384,697421..697423,
                     697514..697516,697652..697654))
                     /locus_tag="COSY_0666"
                     /note="putative catalytic residues [active]"
                     /db_xref="CDD:239333"
     gene            complement(697678..698310)
                     /locus_tag="COSY_0667"
                     /db_xref="GeneID:5172703"
     CDS             complement(697678..698310)
                     /locus_tag="COSY_0667"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219503.1"
                     /db_xref="GI:148244809"
                     /db_xref="GeneID:5172703"
                     /translation="MIESKIISITLLLAVVIFTLFYLLTRNIQIPQNQSMPWQSFINS
                     QGNTVVFNLTMGHSSLIDAMHLFGSEAEIAMFGSESKEPELEVFFSNTKVGGISVGVI
                     LNLIFDQKDTKYLNNNIKELRVMSSGVRKTTFNLMAKISMLDLKIKSLTLIPKVDLSK
                     EIIINLFGEPSRVELVSQSVSYWYYLIKGVRIIIDDDNKEILEFYNEVVQ"
     gene            complement(698314..698727)
                     /locus_tag="COSY_0668"
                     /db_xref="GeneID:5172582"
     CDS             complement(698314..698727)
                     /locus_tag="COSY_0668"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219504.1"
                     /db_xref="GI:148244810"
                     /db_xref="GeneID:5172582"
                     /translation="MLVDSIVVLINQLDDILVIMGIISGVIFIISLLLIPYLLGLMPS
                     NYFLKNSEKKLKIRRPFNLIKLILKTLTGFILLIVGIIMLVTPGQGLISILLGLFLME
                     FPGKRQLELKLINHNLTFKTLNWLRSKANKPLFKR"
     misc_feature    complement(698401..698520)
                     /locus_tag="COSY_0668"
                     /note="Putative transmembrane protein (PGPGW); Region:
                     PGPGW; pfam09656"
                     /db_xref="CDD:150350"
     gene            complement(699148..701181)
                     /gene="glyS"
                     /locus_tag="COSY_0669"
                     /db_xref="GeneID:5172575"
     CDS             complement(699148..701181)
                     /gene="glyS"
                     /locus_tag="COSY_0669"
                     /EC_number="6.1.1.14"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-tRNA synthetase beta subunit"
                     /protein_id="YP_001219505.1"
                     /db_xref="GI:148244811"
                     /db_xref="GeneID:5172575"
                     /translation="MNTQDFLLELGCEELPPKNLQHLSNALTYNLTTEFDKLKLSYSS
                     VESFATPRRLAVLVNGLQLQQNNQTIERKGPLISELDKAIEGFAKSCGVARNMLTQKA
                     FGKIQYYFFTKQQIGLKTIDLLESVVNTAIQNIPIAKPMRWSNLDTYFVRPVHWLIMM
                     LGSDVVPASIMGLISSNITRGLRFTDECIFDIICAKDYQKTLLEKAQIEVDFDMRKAI
                     IRKQIIHVAQNNNATAVIDESLLDEVCALVEYPCVFSGNFSSKFLDIPEEVLISVMKS
                     YQKYFHMLDMNGNLMSSFISVANIESSDLSVIIDGNERVIRSRLSDSEFFWIQDKAYT
                     LEFRLDRLNQVLFMKSLGSMGDKAKRIEILSGYIAGVIGANVKDSSRAGLLCKSDLVT
                     DMVGEFADLQGVMGGYYAFNDGENKAVSVAISEHYQPRFSGDSLPNTIEGLVVSIADK
                     LDTITGIFGIGQGPTGSKDPYALRRMALGLLRIILESKFHINLKELISESLNAHLSVV
                     NTNKANDIYQFMMERLRSYYKKHEVSMQVFDAVLAVCPESPYDFHLRIRALNTFTNNQ
                     ELENLIEINKRISNILKNCSDLSIKVDDSVLIETAEKTLFKATKILAKRISNSINYTK
                     NMKELIALKDMIDEFFDKVMVNTDDVELRQARLNLINWVRSLFLSVADISYLV"
     misc_feature    complement(699151..701175)
                     /gene="glyS"
                     /locus_tag="COSY_0669"
                     /note="glycyl-tRNA synthetase subunit beta; Validated;
                     Region: glyS; PRK01233"
                     /db_xref="CDD:234925"
     misc_feature    complement(699181..699456)
                     /gene="glyS"
                     /locus_tag="COSY_0669"
                     /note="Anticodon-binding domain of class Ia aminoacyl tRNA
                     synthetases and similar domains; Region:
                     Anticodon_Ia_like; cl12020"
                     /db_xref="CDD:245839"
     gene            complement(701896..702288)
                     /locus_tag="COSY_0670"
                     /db_xref="GeneID:5172053"
     CDS             complement(701896..702288)
                     /locus_tag="COSY_0670"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219506.1"
                     /db_xref="GI:148244812"
                     /db_xref="GeneID:5172053"
                     /translation="MDILKLDTKTQSNLTLQLFKILENWHLEDIEQLKLLDLYGVIKP
                     RHLCLYKNLYKLFDFDERLIKRTEIILGVSESLGTTFPINKEYGAIWLKRPVKKFKHK
                     TPLELMLSGDTGMMRVWYFLDCTQGWKN"
     gene            complement(702288..703127)
                     /locus_tag="COSY_0671"
                     /db_xref="GeneID:5172722"
     CDS             complement(702288..703127)
                     /locus_tag="COSY_0671"
                     /note="Similar to the C-terminal region of biopolymer
                     transport protein (colicin import membrane protein) TolA
                     (341 aa) in Thiomicrospira crunogena XCL-2."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219507.1"
                     /db_xref="GI:148244813"
                     /db_xref="GeneID:5172722"
                     /translation="MKFNFFKEIKLPKIVRQCPIAFWVAIALHVVLAIGLLYSNAQRL
                     GIPKQTVKLDEIPKAMMIDLTEIEKEKQRLINIKQRREKRLEELQRTEKKVENERYKE
                     QQRLKQLKIKIKQEKKAKIIAEIKRKQAEREALKAENKKQEIEKLRQVEAKKFKKEQN
                     KRFLKKEVQAEEDQDRLIAQEDILNELKFNYINQIASRVKEKWHYQGAKDSWSCDVQI
                     LQDLDGQVKSVNLKSCNIDNIIKVQSFKDSIERAVYKASPLPYAPDRSVFDAQILFHF
                     KVN"
     misc_feature    complement(702324..702557)
                     /locus_tag="COSY_0671"
                     /note="Gram-negative bacterial tonB protein; Region: TonB;
                     cl10048"
                     /db_xref="CDD:245245"
     gene            complement(703127..703579)
                     /gene="tolR"
                     /locus_tag="COSY_0672"
                     /db_xref="GeneID:5172708"
     CDS             complement(703127..703579)
                     /gene="tolR"
                     /locus_tag="COSY_0672"
                     /note="Tol biopolymer transport system.
                     TonB-ExbB-ExbD/TolA-TolQ-TolR (Exb) family"
                     /codon_start=1
                     /transl_table=11
                     /product="biopolymer transport protein TolR"
                     /protein_id="YP_001219508.1"
                     /db_xref="GI:148244814"
                     /db_xref="GeneID:5172708"
                     /translation="MIELLKRHRLVIDAQINIVPYIDVMLVLLVIFMMTTPIIEQGIE
                     VDLPFAEAKIVDFTQQPTIITIDKQGKYFINSLNEMDSDVVVIGEKLPLGVIVGRVNA
                     RLEIYPKMKVFVRGDRQVDYGSVVSLMSILQKNGVDKVGIVTESPDLR"
     misc_feature    complement(703136..703546)
                     /gene="tolR"
                     /locus_tag="COSY_0672"
                     /note="Biopolymer transport protein [Intracellular
                     trafficking and secretion]; Region: ExbD; COG0848"
                     /db_xref="CDD:223917"
     misc_feature    complement(703145..703540)
                     /gene="tolR"
                     /locus_tag="COSY_0672"
                     /note="TolR protein; Region: tolR; TIGR02801"
                     /db_xref="CDD:234020"
     gene            complement(703572..704264)
                     /gene="tolQ"
                     /locus_tag="COSY_0673"
                     /db_xref="GeneID:5172225"
     CDS             complement(703572..704264)
                     /gene="tolQ"
                     /locus_tag="COSY_0673"
                     /note="Tol biopolymer transport system.
                     TonB-ExbB-ExbD/TolA-TolQ-TolR (Exb) family"
                     /codon_start=1
                     /transl_table=11
                     /product="biopolymer transport protein TolQ"
                     /protein_id="YP_001219509.1"
                     /db_xref="GI:148244815"
                     /db_xref="GeneID:5172225"
                     /translation="MDNGLSIFSLILSAGFVVQVVMFILVLMSIYSWTLILSKKKILI
                     DTNKSIKFFYQKFSTNVDLEKLAYQTFQESTNQSSMERIFNAGYQELNYTTSDSSQEL
                     IINAERAYRIMNITANNEVDYLDDGLSILAMIASSSPYIGLFGTVWGIMHSFIGLASV
                     KQATIAIVAPGIAEALIATAFGLFSAIPATIAYNRLITKVGMINNKYSVFVEQLFVLF
                     QRQKNKLKIEND"
     misc_feature    complement(703605..704249)
                     /gene="tolQ"
                     /locus_tag="COSY_0673"
                     /note="TolQ protein; Region: tolQ; TIGR02796"
                     /db_xref="CDD:131843"
     gene            complement(704657..705685)
                     /gene="ruvB"
                     /locus_tag="COSY_0674"
                     /db_xref="GeneID:5172215"
     CDS             complement(704657..705685)
                     /gene="ruvB"
                     /locus_tag="COSY_0674"
                     /EC_number="3.1.22.4"
                     /note="promotes strand exchange during homologous
                     recombination; RuvAB complex promotes branch migration;
                     RuvABC complex scans the DNA during branch migration and
                     resolves Holliday junctions at consensus sequences; forms
                     hexameric rings around opposite DNA arms; requires ATP for
                     branch migration and orientation of RuvAB complex
                     determines direction of migration"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction DNA helicase RuvB"
                     /protein_id="YP_001219510.1"
                     /db_xref="GI:148244816"
                     /db_xref="GeneID:5172215"
                     /translation="MIEEDLLIDEKDHNNEDLVITSIRPNSLENYIGQNDVKSQMMLF
                     IKAAKKRKDTLDHCLIYGPPGLGKTTLANVIANQMSTGFKKTSGPVLERAGDLAAILT
                     KLDPYDILFIDEIHRLNYVVEETLYPALEDFKLDIIVGEGLASHSVQLELPPFTLIGA
                     TTRVGMLTSPLRDRFGIIQRLQFYNVEDLKMIVERSADILDIQIESKGALEIAKRSRG
                     TPRIANRLLRRVRDFADVKANSMIHQDIAKEALIILKVDEAGLEQLDRDYLSIIMNKF
                     SGGPVGLDTLATSIGEERGTLEDMVEPYLIQQGFIMRTPRGRSITDAAYAHLGLINGL
                     KVNDLFNQ"
     misc_feature    complement(704696..705667)
                     /gene="ruvB"
                     /locus_tag="COSY_0674"
                     /note="Holliday junction DNA helicase RuvB; Reviewed;
                     Region: ruvB; PRK00080"
                     /db_xref="CDD:234619"
     misc_feature    complement(705152..705592)
                     /gene="ruvB"
                     /locus_tag="COSY_0674"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(705479..705502)
                     /gene="ruvB"
                     /locus_tag="COSY_0674"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(705200..705202,705347..705349,
                     705476..705499))
                     /gene="ruvB"
                     /locus_tag="COSY_0674"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(705344..705361)
                     /gene="ruvB"
                     /locus_tag="COSY_0674"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(705164..705166)
                     /gene="ruvB"
                     /locus_tag="COSY_0674"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(704696..704917)
                     /gene="ruvB"
                     /locus_tag="COSY_0674"
                     /note="Holliday junction DNA helicase ruvB C-terminus;
                     Region: RuvB_C; pfam05491"
                     /db_xref="CDD:203257"
     gene            706287..707537
                     /gene="hemA"
                     /locus_tag="COSY_0675"
                     /db_xref="GeneID:5172634"
     CDS             706287..707537
                     /gene="hemA"
                     /locus_tag="COSY_0675"
                     /EC_number="1.2.1.70"
                     /note="catalyzes the formation of glutamate-1-semialdehyde
                     from glutamyl-tRNA(Glu) and NADPH; the second step of the
                     pathway is catalyzed by glutamate-1-semialdehyde
                     aminomutase which results in the formation of
                     5-aminolevulinic acid; functions in porphyrin
                     (tetrapyrroles) biosynthesis; the crystal structure showed
                     a C-terminal dimerization domain that appears to be absent
                     in Chlamydial proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="YP_001219511.1"
                     /db_xref="GI:148244817"
                     /db_xref="GeneID:5172634"
                     /translation="MSQIAILSVNHQLAPVEVREKVAFTPDKLTQALSDLHGIYGIYA
                     CIILSTCNRVEIYVNSDNENPKEVLSNYLAKIHNITRDRINPYLNYFEDNEALTHVCN
                     VATGLDSLVLGEPQILGQLKNAYHMAKEAKTLNKLLEKLFQHAFSTAKKVRTDTQIGV
                     SPVSIAYCSVKLSEKIFECLSEQTVLLIGAGEMIELCAQYLNKKKVSNMIIANRTIEN
                     AQKIANLYQAQSIGLKQFSSVIHKADIIISSTAASVPIIGKGLIESALKKRKHKPIFM
                     LDIAIPRDIEPEVGQLDDIYLYTIDDLEQVINDNIGNREKEKNLAQEIIIKQNQVFNQ
                     WLKVLPNEQLVRSYRSNANLIKNKLLEKAIKQIKHSGDYENIIRKFADQLTNKLLHLP
                     SKNIKQTSTDNLSQCEGCIPNIKK"
     misc_feature    706293..707528
                     /gene="hemA"
                     /locus_tag="COSY_0675"
                     /note="glutamyl-tRNA reductase; Reviewed; Region: hemA;
                     PRK00045"
                     /db_xref="CDD:234592"
     misc_feature    706296..707237
                     /gene="hemA"
                     /locus_tag="COSY_0675"
                     /note="NADP-binding domain of glutamyl-tRNA reductase;
                     Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213"
                     /db_xref="CDD:133452"
     misc_feature    order(706344..706346,706434..706436,706632..706634,
                     706641..706643,706653..706655,706662..706664,
                     706674..706676)
                     /gene="hemA"
                     /locus_tag="COSY_0675"
                     /note="tRNA; other site"
                     /db_xref="CDD:133452"
     misc_feature    order(706434..706439,706443..706445,706611..706613,
                     706626..706628,706632..706634,706644..706646)
                     /gene="hemA"
                     /locus_tag="COSY_0675"
                     /note="putative tRNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:133452"
     misc_feature    order(706851..706853,706857..706859,706866..706868)
                     /gene="hemA"
                     /locus_tag="COSY_0675"
                     /note="putative NADP binding site [chemical binding];
                     other site"
                     /db_xref="CDD:133452"
     misc_feature    707247..707495
                     /gene="hemA"
                     /locus_tag="COSY_0675"
                     /note="Glutamyl-tRNAGlu reductase, dimerisation domain;
                     Region: GlutR_dimer; pfam00745"
                     /db_xref="CDD:201424"
     gene            707537..708622
                     /gene="prfA"
                     /locus_tag="COSY_0676"
                     /db_xref="GeneID:5172484"
     CDS             707537..708622
                     /gene="prfA"
                     /locus_tag="COSY_0676"
                     /note="recognizes the termination signals UAG and UAA
                     during protein translation a specificity which is
                     dependent on amino acid residues residing in loops of the
                     L-shaped tRNA-like molecule of RF1; this protein is
                     similar to release factor 2"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="YP_001219512.1"
                     /db_xref="GI:148244818"
                     /db_xref="GeneID:5172484"
                     /translation="MNSSILAKLEQLSIRLEEVSIMLSDPEVVSNVKKFTKLSIEYAQ
                     LTPVNQQFQTYLSHLKNLEDAQLILFEDDMEIKTMAKEEILNTKKILSQLDLKLKKSI
                     LPKDPNDSRNIIIEIRAGTGGDEASIFSGDLFKIYSRYSEKQKWTIEIISSSIGEHGG
                     FKEIIARISGINVYSKLKFESGAHRVQRVPTTESQGRIHTSACTVAIMPEVENIEEIN
                     ININDVRIDTFRASGAGGQHVNKTDSAVRITHLPTGTVVECQDGRSQHKNKAQAMSVL
                     ASRILDAQQQEQQEQQSSTRKELIGSGDRSQRIRTYNYPQGRITDHRINLTLYKLTEI
                     MEGNLSAIIKPLIIEQQTNQLTELNNT"
     misc_feature    707540..708616
                     /gene="prfA"
                     /locus_tag="COSY_0676"
                     /note="peptide chain release factor 1; Validated; Region:
                     prfA; PRK00591"
                     /db_xref="CDD:234801"
     misc_feature    707732..708076
                     /gene="prfA"
                     /locus_tag="COSY_0676"
                     /note="This domain is found in peptide chain release
                     factors; Region: PCRF; smart00937"
                     /db_xref="CDD:214923"
     misc_feature    708203..708505
                     /gene="prfA"
                     /locus_tag="COSY_0676"
                     /note="RF-1 domain; Region: RF-1; pfam00472"
                     /db_xref="CDD:201249"
     gene            complement(709041..709844)
                     /locus_tag="COSY_0677"
                     /db_xref="GeneID:5171814"
     CDS             complement(709041..709844)
                     /locus_tag="COSY_0677"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease"
                     /protein_id="YP_001219513.1"
                     /db_xref="GI:148244819"
                     /db_xref="GeneID:5171814"
                     /translation="MSLIHLEDFIFRAILAAIGISIISGSLGCFVIWKRMSYFSESIS
                     HSALLGTSLGFASGLGMHFGLVMVGTIFAIFIVILQRKNFLSNDTILGIFSHIFLSLG
                     IVVLGFIGGTNTDYFSLLFGDILSITNSDIVWVYVILTVLGLLLIIFWQRLLLLTLNE
                     ELAVAQGLNRDFYQLLFMLMIALAVSVSVQIVGVLLITSLLIIPPAVARVFSNTPSSM
                     VFQSVIVSMVAVTIGIIASMFYDVATGPAIVITLGVLFLLSQFAYKKLI"
     misc_feature    complement(709050..709760)
                     /locus_tag="COSY_0677"
                     /note="ABC-type Mn2+/Zn2+ transport systems, permease
                     components [Inorganic ion transport and metabolism];
                     Region: ZnuB; COG1108"
                     /db_xref="CDD:224033"
     misc_feature    complement(709068..709760)
                     /locus_tag="COSY_0677"
                     /note="Transmembrane subunit (TM), of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters involved in the uptake of siderophores, heme,
                     vitamin B12, or the divalent cations Mg2+ and Zn2+.
                     PBP-dependent ABC transporters consist of...; Region:
                     TM_ABC_iron-siderophores_like; cd06550"
                     /db_xref="CDD:119348"
     misc_feature    complement(order(709200..709202,709221..709223,
                     709347..709355,709359..709376,709380..709385,
                     709389..709397,709401..709406,709743..709751))
                     /locus_tag="COSY_0677"
                     /note="ABC-ATPase subunit  interface; other site"
                     /db_xref="CDD:119348"
     misc_feature    complement(order(709074..709079,709086..709088,
                     709095..709100,709107..709109,709254..709256,
                     709482..709484,709491..709496,709530..709535,
                     709542..709544,709551..709556,709563..709568,
                     709575..709580,709725..709727,709740..709742,
                     709746..709748))
                     /locus_tag="COSY_0677"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    complement(order(709116..709118,709131..709133,
                     709266..709268,709278..709280,709452..709454))
                     /locus_tag="COSY_0677"
                     /note="putative PBP binding regions; other site"
                     /db_xref="CDD:119348"
     gene            complement(709835..710242)
                     /gene="fur"
                     /locus_tag="COSY_0678"
                     /db_xref="GeneID:5172700"
     CDS             complement(709835..710242)
                     /gene="fur"
                     /locus_tag="COSY_0678"
                     /codon_start=1
                     /transl_table=11
                     /product="negative regulator of ferric iron uptake"
                     /protein_id="YP_001219514.1"
                     /db_xref="GI:148244820"
                     /db_xref="GeneID:5172700"
                     /translation="MDAQDLKSAGLKVTLPRLKILEILETSDNHHMSAEDIYRTLMIQ
                     GAEVGVATIYRVLTQFEEAGMVNKLNFDNGQSVFELSNVDHHDHLVCIKCGKIDEFSD
                     EVIEQHQHDIANKYGYQLTDHCLYLYGFCKGCH"
     misc_feature    complement(709850..710197)
                     /gene="fur"
                     /locus_tag="COSY_0678"
                     /note="Ferric uptake regulator(Fur) and related
                     metalloregulatory proteins; typically iron-dependent,
                     DNA-binding repressors and activators; Region: Fur_like;
                     cd07153"
                     /db_xref="CDD:133478"
     misc_feature    complement(order(709946..709948,709979..709981,
                     709985..709987,710006..710008,710150..710152))
                     /gene="fur"
                     /locus_tag="COSY_0678"
                     /note="metal binding site 2 [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:133478"
     misc_feature    complement(710054..710098)
                     /gene="fur"
                     /locus_tag="COSY_0678"
                     /note="putative DNA binding helix; other site"
                     /db_xref="CDD:133478"
     misc_feature    complement(order(709874..709876,709925..709927,
                     709982..709984,709988..709990))
                     /gene="fur"
                     /locus_tag="COSY_0678"
                     /note="metal binding site 1 [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:133478"
     misc_feature    complement(order(709853..709879,709883..709891,
                     709916..709921,709967..709975))
                     /gene="fur"
                     /locus_tag="COSY_0678"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:133478"
     misc_feature    complement(order(709850..709852,709961..709963,
                     709970..709972))
                     /gene="fur"
                     /locus_tag="COSY_0678"
                     /note="structural Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:133478"
     gene            710308..710805
                     /locus_tag="COSY_0679"
                     /db_xref="GeneID:5172258"
     CDS             710308..710805
                     /locus_tag="COSY_0679"
                     /note="SmpA/OmlA family protein. Bacterial outer membrane
                     lipoprotein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219515.1"
                     /db_xref="GI:148244821"
                     /db_xref="GeneID:5172258"
                     /translation="MNKLTLIAFLFLFLSACLHKIPGVSLPILYKNDIHQGSILERFK
                     INQLKLGMSKAQVQNLIGSPSIIDTFHNNQWDYINHSTLYKKDDIHYRLILKFNNNNL
                     IHINTSGINSLSQLTDKERKIENKRIRDKQASEKAKVVVKITEEKDLSKAKILKSDPS
                     TLFVN"
     misc_feature    710308..>710616
                     /locus_tag="COSY_0679"
                     /note="Outer membrane lipoprotein OmlA (small protein A)
                     [Cell envelope biogenesis, outer membrane]; Region: OlmA;
                     COG2913"
                     /db_xref="CDD:225465"
     misc_feature    710416..710622
                     /locus_tag="COSY_0679"
                     /note="SmpA / OmlA family; Region: SmpA_OmlA; pfam04355"
                     /db_xref="CDD:202983"
     gene            complement(710873..711832)
                     /locus_tag="COSY_0680"
                     /db_xref="GeneID:5172450"
     CDS             complement(710873..711832)
                     /locus_tag="COSY_0680"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S49"
                     /protein_id="YP_001219516.1"
                     /db_xref="GI:148244822"
                     /db_xref="GeneID:5172450"
                     /translation="MKRTADEQLADIAQEFVRQNKSKYRWRIIFSILFVGYFIFIYYI
                     GISENGVLNTALKKESPFVAEVVLSGTIQSSGSIDADETIELLYSAFKLENAKAIILR
                     INSPGGSPVQSSRIYKAIIRLKKQFDKKFYVVVEDVCASGCYYIASAADEIYADESSI
                     IGSIGVIMSSFGAVDAIKKLGIKRRLYTAGKYKGLLDSFSPENEKILAHIQIHVLDKL
                     HQNFINAVKAGRGNRLSKHKDLFTGLIWLGQDANKLGLIDGIADTNYVAKHIIGIDSR
                     VLFEKEKTLLEQLTEASINGIALAISDKLISKNLIGFLQVDNY"
     misc_feature    complement(711038..711646)
                     /locus_tag="COSY_0680"
                     /note="signal peptide peptidase SppA, 36K type; Region:
                     SppA_dom; TIGR00706"
                     /db_xref="CDD:213553"
     misc_feature    complement(711047..711646)
                     /locus_tag="COSY_0680"
                     /note="Signal peptide peptidase A (SppA), a serine
                     protease, has catalytic Ser-Lys dyad; Region:
                     S49_Sppa_N_C; cd07023"
                     /db_xref="CDD:132934"
     misc_feature    complement(order(711083..711085,711092..711094,
                     711098..711106,711176..711178,711326..711337,
                     711359..711361,711365..711367,711410..711412,
                     711527..711529,711626..711628))
                     /locus_tag="COSY_0680"
                     /note="tandem repeat interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:132934"
     misc_feature    complement(order(711170..711172,711182..711184,
                     711272..711286,711290..711292,711491..711493,
                     711569..711571,711590..711592))
                     /locus_tag="COSY_0680"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:132934"
     misc_feature    complement(711410..711412)
                     /locus_tag="COSY_0680"
                     /note="active site residues [active]"
                     /db_xref="CDD:132934"
     gene            711848..712444
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /db_xref="GeneID:5172518"
     CDS             711848..712444
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /EC_number="3.6.3.41"
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter ATP-binding protein CcmA"
                     /protein_id="YP_001219517.1"
                     /db_xref="GI:148244823"
                     /db_xref="GeneID:5172518"
                     /translation="MLKVDNLSCQKGYNLLFSNLSFKVNSGDILRITGTNGSGKTSLL
                     KILAGLDIQEQGNVFLDNHALKSEAYQQEIFYLGHLSTLSEELSTLENLEFLTKLNKS
                     TKQIQLTKALSSIGLKGYENEYCDKLSAGQKRRVILAGLFISNAKIWLLDEPFTALDT
                     DGVTIIESRITKHCKQGGLCLFTTHQNSDLLNQKVLAL"
     misc_feature    711848..712405
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /note="cytochrome c biogenesis protein CcmA; Provisional;
                     Region: PRK13538"
                     /db_xref="CDD:184125"
     misc_feature    711851..712405
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    711947..711970
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(711956..711961,711965..711973,712082..712084,
                     712301..712306,712400..712402)
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    712073..712084
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    712229..712258
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    712289..712306
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    712313..712324
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    712388..712405
                     /gene="ccmA"
                     /locus_tag="COSY_0681"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            712441..713106
                     /gene="ccmB"
                     /locus_tag="COSY_0682"
                     /db_xref="GeneID:5171926"
     CDS             712441..713106
                     /gene="ccmB"
                     /locus_tag="COSY_0682"
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter membrane protein CcmB"
                     /protein_id="YP_001219518.1"
                     /db_xref="GI:148244824"
                     /db_xref="GeneID:5171926"
                     /translation="MNIYLQALKRDLRIAIRNPSSILNPLLFFIISVSLFPLAISSEA
                     TILSPIGSGIIWVTSMLSMLLSLNALFHHDFENGVLEQMVISHHSLPLLILSKITAHW
                     ILTGIPIILLSPLFGLFLFLDNNGLYVLMITLLLATPSLSLIGAIGASLIVGIKNSGM
                     LLSLLILPLYIPILIFASSAVSQAQFGLGITGQLYFLATVLIVSLMSAPFISGIALKI
                     SLE"
     misc_feature    712462..713091
                     /gene="ccmB"
                     /locus_tag="COSY_0682"
                     /note="heme exporter protein CcmB; Region: ccmB;
                     TIGR01190"
                     /db_xref="CDD:200083"
     gene            713260..714393
                     /gene="metK"
                     /locus_tag="COSY_0683"
                     /db_xref="GeneID:5171950"
     CDS             713260..714393
                     /gene="metK"
                     /locus_tag="COSY_0683"
                     /EC_number="2.5.1.6"
                     /note="catalyzes the formation of S-adenosylmethionine
                     from methionine and ATP; methionine adenosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="YP_001219519.1"
                     /db_xref="GI:148244825"
                     /db_xref="GeneID:5171950"
                     /translation="MIFTSESVSAGHPDKICDQISDAILDAALTQDKNSRVAVETLVK
                     GNHVVLAGEITTGANIDYEKIVRNTIIDIGYDKQEYGFNGNTCNITNLLGEQSQDIAI
                     GVNESSNHEQGAGDQGLMFGYACNATDTLMPAPILYAHLLVARQAKLMKDGVLPWLRP
                     DAKSQVSMIYNGHKIVGIDAVVLSTQHDNDISLTDLRKVILEKIIKPVLPSKWLSNKT
                     QYHINSTGHFVIGGPVGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSTAYAT
                     RYIAKNIVAAGLADRCEIQVSYAIGVAEPISINVETFGTGKINNQAIEHLIHKHFDLR
                     PKGLIEMLDLKRPIYQQTASYGHFGRTENDISWEKTDRAHLLR"
     misc_feature    713260..714390
                     /gene="metK"
                     /locus_tag="COSY_0683"
                     /note="S-adenosylmethionine synthetase; Validated; Region:
                     PRK05250"
                     /db_xref="CDD:235374"
     misc_feature    713263..713550
                     /gene="metK"
                     /locus_tag="COSY_0683"
                     /note="S-adenosylmethionine synthetase, N-terminal domain;
                     Region: S-AdoMet_synt_N; pfam00438"
                     /db_xref="CDD:201226"
     misc_feature    713587..713943
                     /gene="metK"
                     /locus_tag="COSY_0683"
                     /note="S-adenosylmethionine synthetase, central domain;
                     Region: S-AdoMet_synt_M; pfam02772"
                     /db_xref="CDD:217221"
     misc_feature    713947..714366
                     /gene="metK"
                     /locus_tag="COSY_0683"
                     /note="S-adenosylmethionine synthetase, C-terminal domain;
                     Region: S-AdoMet_synt_C; pfam02773"
                     /db_xref="CDD:111646"
     gene            714418..715788
                     /gene="ahcY"
                     /locus_tag="COSY_0684"
                     /db_xref="GeneID:5172088"
     CDS             714418..715788
                     /gene="ahcY"
                     /locus_tag="COSY_0684"
                     /EC_number="3.3.1.1"
                     /note="catalyzes the formation of L-homocysteine from
                     S-adenosyl-L-homocysteine"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-L-homocysteine hydrolase"
                     /protein_id="YP_001219520.1"
                     /db_xref="GI:148244826"
                     /db_xref="GeneID:5172088"
                     /translation="MNNPTLNNKDYKVADMKLADYGRKEIELAEAEMPTLMALREKYK
                     SKQPLKNAKILGCIHMTIQTAVLIETLIDLGSQVRWSSCNIFSTQDHAASAMVAANIP
                     IFAWKGETEEEFLWCIEQTILKNGKPWAANMVLDDGGDLTQILHEKYPEMLANIHGIS
                     EETTTGVHRLLEMMKEGSLKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRSTDMLMS
                     GKKVLVIGYGDVGKGSAQSLRQENMIVKISEIDPICAMQACMDGFEIISPYINGINTG
                     LIDNINKDLLNTTDLIVTATGNINVCDNTMLQTLKPGAVVCNIGHFDNEIDTQYMRDN
                     WRWDEIKPQVHRIFRTDNKNDYLILLSEGRLVNLGNATGHPSRIMDGSFANQVLAQIH
                     LFNAKFADNGGNIYVKVLPKKLDEEVAAGMVYGFNGVLTILTTNQANYINVPKNGPFK
                     PENYKY"
     misc_feature    714427..715767
                     /gene="ahcY"
                     /locus_tag="COSY_0684"
                     /note="S-adenosyl-L-homocysteine hydrolase; Provisional;
                     Region: PRK05476"
                     /db_xref="CDD:235488"
     misc_feature    714475..715749
                     /gene="ahcY"
                     /locus_tag="COSY_0684"
                     /note="S-Adenosylhomocysteine Hydrolase, NAD-binding and
                     catalytic domains; Region: SAHH; cd00401"
                     /db_xref="CDD:240619"
     misc_feature    order(714478..714480,714487..714489,714499..714501,
                     714508..714513,714919..714921,714928..714933,
                     714979..714981,714985..714987,714997..715002,
                     715012..715014,715021..715026,715036..715038,
                     715045..715050,715057..715077,715099..715104,
                     715111..715113,715138..715143,715147..715149,
                     715162..715188,715192..715203,715207..715215,
                     715219..715221,715228..715230,715306..715320,
                     715348..715356,715387..715389,715435..715440,
                     715453..715455,715531..715533,715540..715542,
                     715546..715551,715558..715560,715642..715644,
                     715660..715665,715672..715677,715684..715686,
                     715693..715698,715702..715710,715714..715716,
                     715723..715728,715735..715740)
                     /gene="ahcY"
                     /locus_tag="COSY_0684"
                     /note="homotetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240619"
     misc_feature    order(714592..714594,714598..714600,714604..714609,
                     714826..714828,714901..714906,714991..714993,
                     715003..715005,715519..715521,715534..715539,
                     715552..715554,715564..715566)
                     /gene="ahcY"
                     /locus_tag="COSY_0684"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:240619"
     misc_feature    order(714592..714594,714826..714828,714901..714903,
                     715003..715005)
                     /gene="ahcY"
                     /locus_tag="COSY_0684"
                     /note="catalytic site [active]"
                     /db_xref="CDD:240619"
     misc_feature    order(714904..714912,715006..715008,715018..715020,
                     715093..715095,715099..715107,715159..715170,
                     715177..715179,715300..715311,715318..715320,
                     715372..715380,715510..715512,715516..715518,
                     715537..715539)
                     /gene="ahcY"
                     /locus_tag="COSY_0684"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:240619"
     gene            715880..716803
                     /gene="glyQ"
                     /locus_tag="COSY_0685"
                     /db_xref="GeneID:5171968"
     CDS             715880..716803
                     /gene="glyQ"
                     /locus_tag="COSY_0685"
                     /EC_number="6.1.1.14"
                     /note="glycine--tRNA ligase alpha chain; GlyRS; class II
                     aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2);
                     catalyzes a two-step reaction; first charging a glycine
                     molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP; second by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-tRNA synthetase subunit alpha"
                     /protein_id="YP_001219521.1"
                     /db_xref="GI:148244827"
                     /db_xref="GeneID:5171968"
                     /translation="MLISNLDTCVSFQNLILKLQTFWSSKGCVLLQPFDMEMGAGTFH
                     PATFLRAIGPEPWKAAYVQPSRRPTDGRYGKNPNRLQHYYQFQVLLKPSPINIQDLYL
                     ESLARINIDLTKHDIRFIEDNWESPTLGAWGLGWEVWLNGMEISQFTYFQQVGGLTCK
                     PVSGELTYGLERLSMYLQGVDSVFDLIWVEGISYSDVFHQNEIEQSQYNFEIANTEVL
                     FRQFDEAETMHKKLIERLLPYPAHEQVIKASHLFNLLDARHAISVTDRARFIRKVRAM
                     SQKVAQTYYDSRKALDFPMLKQPTKVKPSKK"
     misc_feature    715910..716746
                     /gene="glyQ"
                     /locus_tag="COSY_0685"
                     /note="Class II Glycyl-tRNA synthetase (GlyRS) alpha
                     subunit core catalytic domain. GlyRS functions as a
                     homodimer in eukaryotes, archaea and some bacteria and as
                     a heterotetramer in the remainder of prokaryotes and in
                     arabidopsis. It is responsible for the...; Region:
                     GlyRS_alpha_core; cd00733"
                     /db_xref="CDD:238375"
     misc_feature    order(715916..715918,715928..715930,715940..715942,
                     715964..715969,715973..715975,715979..715990,
                     716036..716038,716063..716065,716075..716077,
                     716123..716125,716441..716443,716480..716482,
                     716489..716494,716513..716515,716519..716521,
                     716528..716530,716537..716542,716549..716554,
                     716561..716563,716570..716572,716582..716584,
                     716588..716599,716606..716608,716618..716620)
                     /gene="glyQ"
                     /locus_tag="COSY_0685"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238375"
     misc_feature    715961..715984
                     /gene="glyQ"
                     /locus_tag="COSY_0685"
                     /note="motif 1; other site"
                     /db_xref="CDD:238375"
     misc_feature    order(715997..715999,716003..716005,716078..716080,
                     716126..716128,716132..716134,716138..716146,
                     716309..716314,716324..716326,716372..716377,
                     716381..716386,716390..716395)
                     /gene="glyQ"
                     /locus_tag="COSY_0685"
                     /note="active site"
                     /db_xref="CDD:238375"
     misc_feature    716075..716086
                     /gene="glyQ"
                     /locus_tag="COSY_0685"
                     /note="motif 2; other site"
                     /db_xref="CDD:238375"
     misc_feature    716384..716395
                     /gene="glyQ"
                     /locus_tag="COSY_0685"
                     /note="motif 3; other site"
                     /db_xref="CDD:238375"
     gene            716805..717377
                     /locus_tag="COSY_0686"
                     /db_xref="GeneID:5172074"
     CDS             716805..717377
                     /locus_tag="COSY_0686"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219522.1"
                     /db_xref="GI:148244828"
                     /db_xref="GeneID:5172074"
                     /translation="MNIFSKIYLRILNWVESKYTIYYLSVVSFLESSILPYPPPDIIL
                     VPMTLKHPEKAYYFAFICTIFSVFGGLTGYFLGEVLLQFLLNFELIKPESVTYIKTSF
                     NTYGIWVVGIVAFSPIPYKLATITAGTMSIALLPFIIISLIARATRYYLVVSLIKAYG
                     QQYDQWLKKYINHLGYIIIIVIALGAWYAS"
     misc_feature    716811..717284
                     /locus_tag="COSY_0686"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG1238"
                     /db_xref="CDD:224159"
     gene            717358..717843
                     /locus_tag="COSY_0687"
                     /db_xref="GeneID:5172467"
     CDS             717358..717843
                     /locus_tag="COSY_0687"
                     /note="Similar to the C-terrminal region of lipoprotein
                     NlpD peptidase M23."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219523.1"
                     /db_xref="GI:148244829"
                     /db_xref="GeneID:5172467"
                     /translation="MLGMPVKFLALGLGLLLITSCFYSQQEVIIIEKSTNLQNIKKIS
                     KKINKWSMPVEGNIRKTFSIKNKHLGLTFDTNTGKNVRTIRNGEVVYAGNKIKNHGKM
                     IIIRHPFGFYSSYTQNKTLMVKNGDFVNKGQIIAITSKVPFYFEMKKFQQPINPLKYL
                     K"
     misc_feature    717556..717825
                     /locus_tag="COSY_0687"
                     /note="Peptidase family M23; Region: Peptidase_M23;
                     pfam01551"
                     /db_xref="CDD:216566"
     gene            717997..719325
                     /gene="miaB"
                     /locus_tag="COSY_0688"
                     /db_xref="GeneID:5172584"
     CDS             717997..719325
                     /gene="miaB"
                     /locus_tag="COSY_0688"
                     /note="catalyzes the formation of
                     2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at
                     position 37 in tRNAs that read codons beginning with
                     uridine from N6-(dimethylallyl)adenosine (i(6)A)"
                     /codon_start=1
                     /transl_table=11
                     /product="(dimethylallyl)adenosine tRNA
                     methylthiotransferase"
                     /protein_id="YP_001219524.1"
                     /db_xref="GI:148244830"
                     /db_xref="GeneID:5172584"
                     /translation="MINKLYIRTFGCQMNEYDSNKMVDILKHSHDLTLTDDATSADVL
                     LLNTCSIREKAQDKLFHQLGRWSKLKNKNPNLIIGVGGCVASQEGELILKRTPYVDII
                     FGPQTLHRLPNMLNDALNNKKTSIDISFPEIEKFDHLPKPRTNSVTAFVSIMEGCSKY
                     CTFCIVPYTRGEEISRPFNDVINEVKILASQGVREINLLGQNVNAYQGSMNDGEVSDL
                     ALLINIVAKISGIKRIRYTTSHPNQFSDSLIEAYAEVPELVSHLHLPVQSGSDKILRL
                     MKRGYMSIEYKSKIRKLRKIRPDISISSDFIIGFPGENEKDFLDTMILIDEIGFDKSF
                     SFIYSVRPGTPAASYPDDIDIQVKKQRLALIQKTINNNTEHISQLMIGSIQKVLVENI
                     TKKGNELFGRTENMRNTHFKGDKSLIGQIVNVKITKGRGNSLMGDLLTQI"
     misc_feature    717997..719319
                     /gene="miaB"
                     /locus_tag="COSY_0688"
                     /note="(dimethylallyl)adenosine tRNA
                     methylthiotransferase; Provisional; Region: PRK14325"
                     /db_xref="CDD:237673"
     misc_feature    718006..718308
                     /gene="miaB"
                     /locus_tag="COSY_0688"
                     /note="Uncharacterized protein family UPF0004; Region:
                     UPF0004; pfam00919"
                     /db_xref="CDD:216191"
     misc_feature    718462..719064
                     /gene="miaB"
                     /locus_tag="COSY_0688"
                     /note="Radical SAM superfamily. Enzymes of this family
                     generate radicals by combining a 4Fe-4S cluster and
                     S-adenosylmethionine (SAM) in close proximity. They are
                     characterized by a conserved CxxxCxxC motif, which
                     coordinates the conserved iron-sulfur cluster; Region:
                     Radical_SAM; cd01335"
                     /db_xref="CDD:100105"
     misc_feature    order(718465..718467,718471..718473,718477..718479,
                     718483..718491,718591..718593,718597..718602,
                     718705..718713,718789..718791,718915..718917,
                     719008..719010)
                     /gene="miaB"
                     /locus_tag="COSY_0688"
                     /note="FeS/SAM binding site; other site"
                     /db_xref="CDD:100105"
     misc_feature    719128..719313
                     /gene="miaB"
                     /locus_tag="COSY_0688"
                     /note="TRAM domain; Region: TRAM; pfam01938"
                     /db_xref="CDD:110897"
     gene            complement(719726..720406)
                     /locus_tag="COSY_0689"
                     /db_xref="GeneID:5172072"
     CDS             complement(719726..720406)
                     /locus_tag="COSY_0689"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219525.1"
                     /db_xref="GI:148244831"
                     /db_xref="GeneID:5172072"
                     /translation="MNNKLFSGIVVVVSVISIFYFISPSKSYQDLEKQLKVSYILHNP
                     DKKLPSFSLVGHNNNKFDNNNLKGKWTLLSFIYTHCPDVCPTVLIDMSILKSTLIKRG
                     LNIIPNLVAITFDPARDTPSVLKTYVTHFDKDFLGVSGDQVQINQLIKPFGVYYERVV
                     YEKNGKLLVLKNDEPLSKGILESGYLINHTAWIYLLNPDGQIFAGFPTPHDPIKIADD
                     IEFIIKNF"
     misc_feature    complement(719801..720262)
                     /locus_tag="COSY_0689"
                     /note="SCO (an acronym for Synthesis of Cytochrome c
                     Oxidase) family; composed of proteins similar to Sco1, a
                     membrane-anchored protein possessing a soluble domain with
                     a TRX fold. Members of this family are required for the
                     proper assembly of cytochrome c...; Region: SCO; cd02968"
                     /db_xref="CDD:239266"
     misc_feature    complement(719732..>720256)
                     /locus_tag="COSY_0689"
                     /note="Uncharacterized protein SCO1/SenC/PrrC, involved in
                     biogenesis of respiratory and photosynthetic systems
                     [General function prediction only]; Region: COG1999"
                     /db_xref="CDD:224910"
     misc_feature    complement(order(719840..719842,720155..720157,
                     720167..720169))
                     /locus_tag="COSY_0689"
                     /note="Cu(I) binding site [ion binding]; other site"
                     /db_xref="CDD:239266"
     gene            complement(720750..721253)
                     /locus_tag="COSY_0690"
                     /db_xref="GeneID:5172534"
     CDS             complement(720750..721253)
                     /locus_tag="COSY_0690"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219526.1"
                     /db_xref="GI:148244832"
                     /db_xref="GeneID:5172534"
                     /translation="MFNKVKKLILAFIILIILYVSIAMEHYQMNHITSEIMINDPWVR
                     LAPTNASVLGLFMQINNNTNHDIKLLSVNAGDYKRIELHRTVAQDDIMKMVKQEFMII
                     PAKGKLHLKPGSWHIMLISPKLVLHKGDIVMFELIFDNGLTKIVHAEVRIGKKTIDNH
                     HSTEVYH"
     misc_feature    complement(720816..721142)
                     /locus_tag="COSY_0690"
                     /note="Protein of unknown function (DUF461); Region:
                     DUF461; pfam04314"
                     /db_xref="CDD:190941"
     gene            722294..723382
                     /gene="mnmA"
                     /locus_tag="COSY_0691"
                     /db_xref="GeneID:5172665"
     CDS             722294..723382
                     /gene="mnmA"
                     /locus_tag="COSY_0691"
                     /EC_number="2.1.1.61"
                     /note="catalyzes a sulfuration reaction to synthesize
                     2-thiouridine at the U34 position of tRNAs"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-specific 2-thiouridylase MnmA"
                     /protein_id="YP_001219527.1"
                     /db_xref="GI:148244833"
                     /db_xref="GeneID:5172665"
                     /translation="MKNLNKNTKIIVGLSGGVDSSVTALLLLKQGYQVEALFMKNWEE
                     DDKGRYCSAKQDLSDAQNITNKLSIKLHTINFSVDYWNDVFTHFLKEYKKGRTPNPDI
                     LCNQKIKFGAFLKHAISLGADKIATGHYARIAKKNGTYQLKTGLDNNKDQSYFLHLLS
                     QYQLSKSLFPLGETNKIDVRNIATENGFVTAKKKDSTGICFIGERKFSEFLATYLPKQ
                     QGNIVGEQGQFIKHHQGLAFYTIGQRKGLEIGGGFGKSGKPWFVADKCIERNELVVVQ
                     GDHTLLYYQTLNTSKPYWINTPPTLPMTCNAKIRYRQQSQSCMISQDNNKQLKIIFKQ
                     PQRAITPGQSIVFYDNETCLGGAIIEYR"
     misc_feature    722318..723370
                     /gene="mnmA"
                     /locus_tag="COSY_0691"
                     /note="tRNA methyl transferase; Region: tRNA_Me_trans;
                     pfam03054"
                     /db_xref="CDD:217339"
     misc_feature    722318..723370
                     /gene="mnmA"
                     /locus_tag="COSY_0691"
                     /note="tRNA methyl transferase. This family represents
                     tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase
                     which is involved in the biosynthesis of the modified
                     nucleoside 5-methylaminomethyl-2-thiouridine present in
                     the wobble position of some tRNAs; Region: tRNA_Me_trans;
                     cd01998"
                     /db_xref="CDD:238956"
     misc_feature    order(722330..722338,722342..722353,722405..722407,
                     722411..722413)
                     /gene="mnmA"
                     /locus_tag="COSY_0691"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238956"
     gene            723385..723996
                     /locus_tag="COSY_0692"
                     /db_xref="GeneID:5172189"
     CDS             723385..723996
                     /locus_tag="COSY_0692"
                     /note="HflD; UPF0274; in Escherichia coli this protein is
                     peripherally associated with the membrane and appears to
                     act with lambda CII protein; in Haemophilus influenzae a
                     knockout of the HI0638 gene affected paracytosis"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219528.1"
                     /db_xref="GI:148244834"
                     /db_xref="GeneID:5172189"
                     /translation="MNKLREQTLALASILQTTTLIDQLASTGTCDANSNQASLKSIIT
                     SSTKLEEVFNQKQDLLVGIDALKVVLSNKTKCIQHIIFYALALINLEKKLMKNQTLLN
                     QITLEIDLIRNQDFFEISHINSIARLAQLYKSTLGGLNPKIMINGQQIYLSNKHTSNH
                     IRALLLAGIRAVSLWKSQGGKTWHLLLNKKKILNLINTLEGLN"
     misc_feature    723385..723936
                     /locus_tag="COSY_0692"
                     /note="putative lysogenization regulator; Reviewed;
                     Region: PRK00218"
                     /db_xref="CDD:234690"
     gene            724084..724344
                     /gene="rpsT"
                     /locus_tag="COSY_0693"
                     /db_xref="GeneID:5172633"
     CDS             724084..724344
                     /gene="rpsT"
                     /locus_tag="COSY_0693"
                     /note="binds directly to the 16S rRNA and is involved in
                     post-translational inhibition of arginine and ornithine
                     decarboxylase"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="YP_001219529.1"
                     /db_xref="GI:148244835"
                     /db_xref="GeneID:5172633"
                     /translation="MANSASSRKRARQAVKRNKHNSQIRAKVRTFIKKVTYALEAGNK
                     EQAQNCFTIMQKMLDQAVNKGLIHKNQAARKKSRLNSQIKAL"
     misc_feature    724084..724341
                     /gene="rpsT"
                     /locus_tag="COSY_0693"
                     /note="30S ribosomal protein S20; Reviewed; Region: rpsT;
                     PRK00239"
                     /db_xref="CDD:178943"
     gene            724501..724983
                     /locus_tag="COSY_0694"
                     /db_xref="GeneID:5171873"
     CDS             724501..724983
                     /locus_tag="COSY_0694"
                     /note="Smr domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219530.1"
                     /db_xref="GI:148244836"
                     /db_xref="GeneID:5171873"
                     /translation="MISKSDKILFRSTIENSIPINKDKIVLQNLTNKKAFKAYNYITH
                     GSLAGSDIISYAKNSVSPKIIKRMKQGNISHAPILDLHGQTTIEACQSLSEFIHYHQH
                     QKFIHIIHGKGYNSGQDNGILKSQVVSFLRQHPEVLAFNSCPPKDGGTGAVFTLLKQN
                     "
     misc_feature    724507..724980
                     /locus_tag="COSY_0694"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG2840"
                     /db_xref="CDD:225396"
     misc_feature    724735..724974
                     /locus_tag="COSY_0694"
                     /note="Smr domain; Region: Smr; pfam01713"
                     /db_xref="CDD:216658"
     gene            724988..726388
                     /gene="xseA"
                     /locus_tag="COSY_0695"
                     /db_xref="GeneID:5172677"
     CDS             724988..726388
                     /gene="xseA"
                     /locus_tag="COSY_0695"
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="YP_001219531.1"
                     /db_xref="GI:148244837"
                     /db_xref="GeneID:5172677"
                     /translation="MFNIDEVYTISSFLSVCNKTIENNIPTCWLQGEISNLTRPASGH
                     WYFSLKDNTVQVRCALFRFNQRYIKFSPKNGIEVLVRVVPTLYEARGNFQLVIQQIEQ
                     IGIGNLNLAFKQLKKDLDNEGLFDNIHKKPLPNTINTIGVISSSTGAVIQDIIKVLNN
                     RYPFVKILLFDSIVQGQDSIKKLTNALNIADQSGKCDVIIIARGGGSLEDLWAFNEEI
                     LARAIFNAKTPIISAIGHETDTTIADLVSDIRAPTPSFAAMLVTSNRLELLSNTNKLY
                     TQLHQSYRQTLHYYQSRLNQLKLKISNPNKQIDYLNQKLDYLSINLTTRKESIFTLNN
                     AKLNSLFTTLKQHSPIKTIKHAKSLNQMSLNQLKYQIKQIINTNNNMLYLATERLQKI
                     IMALTNKHKARLSIQANSLHYLSPLNILARGFSITSDTKNQVLSSVTNIKINQTIITQ
                     LDNGALYSNIEKIEKN"
     misc_feature    725000..726370
                     /gene="xseA"
                     /locus_tag="COSY_0695"
                     /note="exodeoxyribonuclease VII large subunit; Reviewed;
                     Region: xseA; PRK00286"
                     /db_xref="CDD:234714"
     misc_feature    725066..725299
                     /gene="xseA"
                     /locus_tag="COSY_0695"
                     /note="ExoVII_LU_OBF: A subfamily of OB folds
                     corresponding to the N-terminal OB-fold domain of
                     Escherichia coli exodeoxyribonuclease VII (ExoVII) large
                     subunit. E. coli ExoVII is composed of two non-identical
                     subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF;
                     cd04489"
                     /db_xref="CDD:239935"
     misc_feature    order(725072..725074,725216..725218,725222..725224,
                     725228..725230,725288..725290)
                     /gene="xseA"
                     /locus_tag="COSY_0695"
                     /note="generic binding surface II; other site"
                     /db_xref="CDD:239935"
     misc_feature    order(725087..725095,725123..725134,725138..725140,
                     725156..725164,725168..725170,725213..725215,
                     725234..725242,725267..725275)
                     /gene="xseA"
                     /locus_tag="COSY_0695"
                     /note="generic binding surface I; other site"
                     /db_xref="CDD:239935"
     gene            727340..727579
                     /locus_tag="COSY_0696"
                     /db_xref="GeneID:5172598"
     CDS             727340..727579
                     /locus_tag="COSY_0696"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219532.1"
                     /db_xref="GI:148244838"
                     /db_xref="GeneID:5172598"
                     /translation="MSSTVDNSNIRGNILMLSTLIITFILPLILIILSYIGIISGTSE
                     YIYAFAVITSMIYIVGGTIWMFTQDLKDSKQLFDG"
     gene            727955..728683
                     /gene="ispD"
                     /locus_tag="COSY_0697"
                     /db_xref="GeneID:5172680"
     CDS             727955..728683
                     /gene="ispD"
                     /locus_tag="COSY_0697"
                     /EC_number="2.7.7.60"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="YP_001219533.1"
                     /db_xref="GI:148244839"
                     /db_xref="GeneID:5172680"
                     /translation="MSNDYYLIIPAGGIGTRMHSEKDNINRKIKIAKQYLKLDNGLTI
                     LDQTLKILLNIDQIKGCIIALANKDYLFTKSKFNNHSKLITTVIGGKKRMNSVFNGLK
                     ALTNLAKDDDWILVHDSVRPCVKASEIINLMNQLKHHETGGLLATKVVDTIKQASNNI
                     VNTTIDRSNLWQAQTPQMYRFGVLLKALNTVINDGMNITDEASAIEYLRLKSVLVKSS
                     KSNIKITNSEDLELANFYLTQYKE"
     misc_feature    727967..728653
                     /gene="ispD"
                     /locus_tag="COSY_0697"
                     /note="CDP-ME synthetase is involved in
                     mevalonate-independent isoprenoid production; Region:
                     CDP-ME_synthetase; cd02516"
                     /db_xref="CDD:133009"
     misc_feature    order(727982..727984,727988..728005,728051..728053,
                     728222..728233,728240..728242,728306..728314,
                     728621..728623)
                     /gene="ispD"
                     /locus_tag="COSY_0697"
                     /note="substrate binding site; other site"
                     /db_xref="CDD:133009"
     misc_feature    order(728315..728317,728372..728374,728399..728401,
                     728405..728407,728456..728473,728549..728554,
                     728558..728563,728570..728572,728585..728596,
                     728606..728611)
                     /gene="ispD"
                     /locus_tag="COSY_0697"
                     /note="dimer interface; other site"
                     /db_xref="CDD:133009"
     gene            728680..729150
                     /gene="ispF"
                     /locus_tag="COSY_0698"
                     /db_xref="GeneID:5172714"
     CDS             728680..729150
                     /gene="ispF"
                     /locus_tag="COSY_0698"
                     /EC_number="4.6.1.12"
                     /note="catalyzes the conversion of
                     4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate
                     into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="YP_001219534.1"
                     /db_xref="GI:148244840"
                     /db_xref="GeneID:5172714"
                     /translation="MKIKTGLGQDSHAFCDTNKLLILAGVVFDYPKSLNANSDGDVVF
                     HSITNAISSITGINILGAKADTLCKQGVTDSVEYLKLAFNDLNKWKIQHIAISIECLH
                     PKILPMIEKMKLSISKLLNIALQDVGITTTTGEGLTEFGKGNGIQVLSIVTVIK"
     misc_feature    728689..729141
                     /gene="ispF"
                     /locus_tag="COSY_0698"
                     /note="MECDP_synthase
                     (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase),
                     encoded by the ispF gene, catalyzes the formation of
                     2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the
                     non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid
                     biosynthesis; Region: MECDP_synthase; cd00554"
                     /db_xref="CDD:100025"
     misc_feature    order(728689..728694,728698..728700,728704..728706,
                     728710..728718,728728..728730,728836..728838,
                     728842..728847,728851..728856,728956..728958,
                     728962..728964,728968..728970,728989..728991,
                     728995..728997,729061..729063,729067..729072,
                     729079..729087,729124..729126,729130..729132,
                     729136..729138)
                     /gene="ispF"
                     /locus_tag="COSY_0698"
                     /note="homotrimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:100025"
     misc_feature    order(728707..728709,728713..728715,728812..728814)
                     /gene="ispF"
                     /locus_tag="COSY_0698"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:100025"
     misc_feature    order(728854..728856,728860..728862,728977..728982,
                     728986..728997,729070..729078)
                     /gene="ispF"
                     /locus_tag="COSY_0698"
                     /note="CDP-binding sites; other site"
                     /db_xref="CDD:100025"
     gene            729150..730559
                     /gene="murC"
                     /locus_tag="COSY_0699"
                     /db_xref="GeneID:5172736"
     CDS             729150..730559
                     /gene="murC"
                     /locus_tag="COSY_0699"
                     /EC_number="6.3.2.8"
                     /note="Catalyzes the formation of
                     UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate
                     and L-alanine in peptidoglycan synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="YP_001219535.1"
                     /db_xref="GI:148244841"
                     /db_xref="GeneID:5172736"
                     /translation="MKDLRMVFKSRITNIHFVGIAGSGMSGIAEVLHNLGYGVSGSDI
                     SQNKITDRLKEMGCQIYYKHHQDNIKNAQAVVISSAIKDNNPEVIKAHQLNIPIVPRA
                     EMLAELMRFRFGIAIAGTHGKTTTTSIITHILNMAELDPTYIIGGILNSSGINAKLGE
                     SDYLIAEADESDASFLHLQSMLSVITNIDHEHMATYNNDYQKLKDAFVSFSANLPFYG
                     TCIICIDDKGVNEILSDIHRPIITYGFNNGADIQAINIKQVDMQMHFDIIYDKYTKPF
                     PIKLNLIGKHNILNTLAAIGICCELNIKVNIIQKALANFSGVARRLDYHGKLNINNLQ
                     ISLFDDYGHHPKEISAVFESLKDTYQNKRLVVIFQPHRYSRTHDLFDNFTRILSTADA
                     LILLDIYPAQEKPIAHINSSTLADAIRKYSSLNPVVIKNQKKILDILPNIVHNNDVLL
                     TLGAGDIHTLPELLKFNYT"
     misc_feature    729165..730544
                     /gene="murC"
                     /locus_tag="COSY_0699"
                     /note="UDP-N-acetylmuramate--L-alanine ligase;
                     Provisional; Region: murC; PRK00421"
                     /db_xref="CDD:234757"
     misc_feature    729192..729488
                     /gene="murC"
                     /locus_tag="COSY_0699"
                     /note="Mur ligase family, catalytic domain; Region:
                     Mur_ligase; pfam01225"
                     /db_xref="CDD:216373"
     misc_feature    <729627..730013
                     /gene="murC"
                     /locus_tag="COSY_0699"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:219763"
     misc_feature    730101..730370
                     /gene="murC"
                     /locus_tag="COSY_0699"
                     /note="Mur ligase family, glutamate ligase domain; Region:
                     Mur_ligase_C; pfam02875"
                     /db_xref="CDD:217262"
     gene            730571..731404
                     /gene="murB"
                     /locus_tag="COSY_0700"
                     /db_xref="GeneID:5172027"
     CDS             730571..731404
                     /gene="murB"
                     /locus_tag="COSY_0700"
                     /EC_number="1.1.1.158"
                     /note="UDP-N-acetylmuramate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylenolpyruvoylglucosamine reductase"
                     /protein_id="YP_001219536.1"
                     /db_xref="GI:148244842"
                     /db_xref="GeneID:5172027"
                     /translation="MILRNESMNSHCSFRTGGLAQYFFIPNDLKDLSNFLKINTKPLL
                     FLGLGSNLLIRDQGFKGVVIKLSNLKQTKIEKNTIWVEAGVTLAKLSRLCYANCLYGG
                     EFLSAIPGTVGGALMMNAGAFGFEFWQHVVSVTTINQLGIVFKRTKDNFNIGYRHVHA
                     QHSNEYFINATLTFNQTKPQKDIKQLLDKRNQYQPTGKASCGSVFKNPKNYFAAKLIE
                     ESQLKGVCIGGACISNKHTNFIINQNKASSSDIINLITHIQQTVKSNFDIDLELEVII
                     K"
     misc_feature    730574..731398
                     /gene="murB"
                     /locus_tag="COSY_0700"
                     /note="UDP-N-acetylenolpyruvoylglucosamine reductase;
                     Provisional; Region: murB; PRK13905"
                     /db_xref="CDD:237553"
     misc_feature    730628..731005
                     /gene="murB"
                     /locus_tag="COSY_0700"
                     /note="FAD binding domain; Region: FAD_binding_4;
                     pfam01565"
                     /db_xref="CDD:216574"
     misc_feature    731120..731398
                     /gene="murB"
                     /locus_tag="COSY_0700"
                     /note="UDP-N-acetylenolpyruvoylglucosamine reductase,
                     C-terminal domain; Region: MurB_C; pfam02873"
                     /db_xref="CDD:111727"
     gene            731401..732282
                     /gene="ddl"
                     /locus_tag="COSY_0701"
                     /db_xref="GeneID:5172037"
     CDS             731401..732282
                     /gene="ddl"
                     /locus_tag="COSY_0701"
                     /EC_number="6.3.2.4"
                     /note="D-alanine--D-alanine ligase; DdlA; DdlB;
                     cytoplasmic; catalyzes the formation of D-alanyl-D-alanine
                     from two D-alanines in peptidoglycan synthesis; there are
                     two forms of this enzyme in Escherichia coli"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="YP_001219537.1"
                     /db_xref="GI:148244843"
                     /db_xref="GeneID:5172037"
                     /translation="MIAILMGGNSAERAISLKSGEAIYQTLNNQNIDCFTFDWYGDNL
                     SEFWQQEFDQVFIILHGRGGEDGYIQKQLENRGICYTGSDSNASHNSMDKARTKIIWE
                     QHSLTLAPSIIANIDQPINPINFPLPWAVKPTLEGSSIGISKVDNQMQLNDALMLAWQ
                     YAPYALIEQWIKGDEYTVAILGDKALPVVRIITDQNFYDYESKYHSNKTQYLCPCNLS
                     LTQEKALQAIALKAFFAINAKGWGRVDFIINQHNKPYLLEINTVPGMTSHSLVPMAAK
                     AIGISFNKLVTSIINEI"
     misc_feature    731404..732270
                     /gene="ddl"
                     /locus_tag="COSY_0701"
                     /note="D-alanine--D-alanine ligase; Reviewed; Region: ddl;
                     PRK01372"
                     /db_xref="CDD:234948"
     misc_feature    731404..731649
                     /gene="ddl"
                     /locus_tag="COSY_0701"
                     /note="D-ala D-ala ligase N-terminus; Region:
                     Dala_Dala_lig_N; pfam01820"
                     /db_xref="CDD:216721"
     misc_feature    731779..732270
                     /gene="ddl"
                     /locus_tag="COSY_0701"
                     /note="ATP-grasp domain; Region: ATP-grasp_4; cl17255"
                     /db_xref="CDD:247809"
     gene            complement(733472..733780)
                     /gene="bolA"
                     /locus_tag="COSY_0702"
                     /db_xref="GeneID:5172216"
     CDS             complement(733472..733780)
                     /gene="bolA"
                     /locus_tag="COSY_0702"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein BolA"
                     /protein_id="YP_001219538.1"
                     /db_xref="GI:148244844"
                     /db_xref="GeneID:5172216"
                     /translation="MNNMQQHLTEQLQIALSPSYLEVFNESHNHSGPSSESHFKLIVV
                     SDYFDDLKLIERHRFINQLFKEEMTYIHALSIHTYTSDEWQMKNGVPDSPKCVGSSTS
                     "
     misc_feature    complement(733478..733771)
                     /gene="bolA"
                     /locus_tag="COSY_0702"
                     /note="BolA-like protein; Region: BolA; cl00386"
                     /db_xref="CDD:241831"
     gene            734693..735610
                     /gene="miaA"
                     /locus_tag="COSY_0703"
                     /db_xref="GeneID:5172502"
     CDS             734693..735610
                     /gene="miaA"
                     /locus_tag="COSY_0703"
                     /EC_number="2.5.1.75"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA delta(2)-isopentenylpyrophosphate
                     transferase"
                     /protein_id="YP_001219539.1"
                     /db_xref="GI:148244845"
                     /db_xref="GeneID:5172502"
                     /translation="MPIQINKTVIFLMGPTASGKTNLAIKLSQQFKTRLISVDSALIY
                     KGMNIGTAKPDKATLKKYPHYLINICSPESSYSVFDFIRDANKQIKTAFAKNELPILV
                     GGTSFYFHVLEHGLSNLPESSTKSKEKFNQLLRNKGTIKLHQDLKKIDPQAANKIHPN
                     DSQRIIRALEVFNLSGKTISELQGNKKPIIDYPIKKIILMPKRNELHTKIETRFLLMM
                     KNGFLNEVQHLKQNPNLHQNLSSIRCVGYRQAWQYLNGKIDKTEMIEKIIIATRQLCK
                     RQITWLKSEKYALVLNNSNLAKAVTFINS"
     misc_feature    734705..735568
                     /gene="miaA"
                     /locus_tag="COSY_0703"
                     /note="tRNA delta(2)-isopentenylpyrophosphate transferase
                     [Translation, ribosomal structure and biogenesis]; Region:
                     MiaA; COG0324"
                     /db_xref="CDD:223401"
     misc_feature    734708..735607
                     /gene="miaA"
                     /locus_tag="COSY_0703"
                     /note="tRNA delta(2)-isopentenylpyrophosphate transferase;
                     Reviewed; Region: miaA; PRK00091"
                     /db_xref="CDD:234626"
     gene            complement(735779..737077)
                     /gene="murD"
                     /locus_tag="COSY_0704"
                     /db_xref="GeneID:5172075"
     CDS             complement(735779..737077)
                     /gene="murD"
                     /locus_tag="COSY_0704"
                     /EC_number="6.3.2.9"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanine--D-glutamate ligase"
                     /protein_id="YP_001219540.1"
                     /db_xref="GI:148244846"
                     /db_xref="GeneID:5172075"
                     /translation="MKLILGLGKTGFSIARFLSEQNINYKIADSRMNPPFLSKYTSLL
                     FKSKPILGIWTSSLLIEVDEVFISPGIAQSETIVGWAMKKNIPIVSDIELFSRFAKAP
                     VIGITGSNGKSTVTKLLTQMIADSGMLVAIGGNIGIPALDCLNEKIEYYVLELSSYQL
                     DYSYHLNLITGVVLNITPDHLDRYSSFEYYIHSKLSLYQYCQYSVVNLDEPLIPKQTN
                     VKYFGINIPKRANDFGTVTCHNICYLLKGNNTLMSVDEVQLIGEHNTKNILAALALGD
                     QIKLPISSMIQSIKNFKALEHRLEWVIKKQNIDYYNDSKATNAISTIIAIQTLMYKHQ
                     NIVLILGGIAKKEDYTLLFKFINKGITGVVLIGQSTRQFLQEINTNSIIYANTNTMQE
                     AVNIARSMISNGVILLSPGCASFDMFDNFEHRGRVFKDCI"
     misc_feature    complement(735782..737074)
                     /gene="murD"
                     /locus_tag="COSY_0704"
                     /note="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
                     synthetase; Provisional; Region: murD; PRK03803"
                     /db_xref="CDD:235160"
     misc_feature    complement(736286..736759)
                     /gene="murD"
                     /locus_tag="COSY_0704"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:219763"
     gene            737138..737797
                     /locus_tag="COSY_0705"
                     /db_xref="GeneID:5172025"
     CDS             737138..737797
                     /locus_tag="COSY_0705"
                     /note="testis-enhanced gene transfer (TEGT) family"
                     /codon_start=1
                     /transl_table=11
                     /product="carrier/transport protein"
                     /protein_id="YP_001219541.1"
                     /db_xref="GI:148244847"
                     /db_xref="GeneID:5172025"
                     /translation="MNTNVNTQIRDTNINSILRNTYQLLSATLLFSGLMAYFAMSLNL
                     PNFGFLITLGGYFGLLYLTNKFKNSSYGILAVFALTGFMGLTLGPIISAYTTTFSNGS
                     ELIAMAMTGTGLIFLSLSFYAVTSGKDFSFLSGFLTAGVIVAFLAGIAAYFFAIPALS
                     LTVSVAFILLMSGLILFETSNIIHGGETNYIMATVTLFISIYNLFLSLLQLLGVFSGE
                     D"
     misc_feature    737138..737794
                     /locus_tag="COSY_0705"
                     /note="Integral membrane protein, interacts with FtsH
                     [General function prediction only]; Region: COG0670"
                     /db_xref="CDD:223742"
     misc_feature    737180..737788
                     /locus_tag="COSY_0705"
                     /note="YccA-like proteins; Region: YccA_like; cd10433"
                     /db_xref="CDD:198415"
     gene            738300..739586
                     /gene="thrA"
                     /locus_tag="COSY_0706"
                     /db_xref="GeneID:5172662"
     CDS             738300..739586
                     /gene="thrA"
                     /locus_tag="COSY_0706"
                     /EC_number="1.1.1.3"
                     /note="catalyzes the formation of L-aspartate
                     4-semialdehyde from L-homoserine"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="YP_001219542.1"
                     /db_xref="GI:148244848"
                     /db_xref="GeneID:5172662"
                     /translation="MLLVNIGILGLGTVGGGVVNVLNKNQKQIIRRSGNNINVTHAAV
                     RDITQTRICPTKNIKLTQDPFQIVNNDDISVVLELMGGVGLAKNLIEQAIKNGKHVVT
                     ANKALIATYGNELLALAKDYNTHLLFEAAVAGGIPILKSLKDGLSANQIELVAGIING
                     TSNFILTEMHNKDRNFQDALKEAKALGYAEANPTFDVEGIDTAHKLAILASMAFGCEL
                     QFNQITTEGISNISSEDITYATKLGYTIKHIGIAKKLNDKLQMHVRPTLVPTTHLLSN
                     VNGVMNGILIKGNAVGETLYYGAGAGDEATASSVIADLIDIIRNTANHDIFGWKSLIN
                     ITKCNTNSIASIFYLRLLVTNKSGIVKDIKKTLANYDINIEAILQKKINQKNDLHIAL
                     ITNLTNNSKINKAVTDIQKYDYIIDEIKIIFVETLN"
     misc_feature    738372..739259
                     /gene="thrA"
                     /locus_tag="COSY_0706"
                     /note="Homoserine dehydrogenase [Amino acid transport and
                     metabolism]; Region: ThrA; COG0460"
                     /db_xref="CDD:223536"
     misc_feature    738381..738686
                     /gene="thrA"
                     /locus_tag="COSY_0706"
                     /note="Homoserine dehydrogenase, NAD binding domain;
                     Region: NAD_binding_3; pfam03447"
                     /db_xref="CDD:217564"
     misc_feature    738708..739241
                     /gene="thrA"
                     /locus_tag="COSY_0706"
                     /note="Homoserine dehydrogenase; Region: Homoserine_dh;
                     pfam00742"
                     /db_xref="CDD:216092"
     misc_feature    739338..>739517
                     /gene="thrA"
                     /locus_tag="COSY_0706"
                     /note="ACT domains are commonly involved in specifically
                     binding an amino acid or other small ligand leading to
                     regulation of the enzyme; Region: ACT; cl09141"
                     /db_xref="CDD:245020"
     gene            739597..740661
                     /gene="thrC"
                     /locus_tag="COSY_0707"
                     /db_xref="GeneID:5172558"
     CDS             739597..740661
                     /gene="thrC"
                     /locus_tag="COSY_0707"
                     /EC_number="4.2.3.1"
                     /note="catalyzes the formation of L-threonine from
                     O-phospho-L-homoserine"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="YP_001219543.1"
                     /db_xref="GI:148244849"
                     /db_xref="GeneID:5172558"
                     /translation="MRYTGLIEYYKDRLPVNDNTKLISLGEGNTPLIQLVNLPKELSK
                     DVDIYIKYEGLNPTGSFKDRGMTMAVTKALESGSKAIICASTGNTSASAAAYAARAGI
                     KAFVLIPEGKITLGKLAQAMMHSAIIIQIKGNFDDGMRLVKEVSEHVSVSIVNSINPF
                     RLQGQKTAAFEIIEELGFAPDYHCLPVGNAGNISSHCMGYSELYKEGKVNNMPKMIGY
                     QAAGSAPFVKGIMIDNPETIATAIRIGHPQNWDLAQKVKKESKGWFSSLTDEKILSTQ
                     KLLSEREGIFCEPASATALAGAIHDIKSGKIVNGSKIVCTLTGHGLKDSDTAISQCNN
                     QIININPVISEVKNAIYNNM"
     misc_feature    739603..740580
                     /gene="thrC"
                     /locus_tag="COSY_0707"
                     /note="threonine synthase; Reviewed; Region: PRK06721"
                     /db_xref="CDD:136018"
     misc_feature    739615..740568
                     /gene="thrC"
                     /locus_tag="COSY_0707"
                     /note="Threonine synthase is a pyridoxal phosphate (PLP)
                     dependent enzyme that catalyses the last reaction in the
                     synthesis of  threonine from aspartate. It proceeds by
                     converting O-phospho-L-homoserine (OPH) into threonine and
                     inorganic phosphate. In plants; Region: Thr-synth_1;
                     cd01563"
                     /db_xref="CDD:107206"
     misc_feature    order(739672..739674,739687..739692,739762..739764,
                     739831..739833,739879..739881,739888..739893,
                     739909..739911,739960..739980,739984..739992,
                     740026..740031,740119..740121,740434..740442,
                     740446..740451,740554..740556)
                     /gene="thrC"
                     /locus_tag="COSY_0707"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107206"
     misc_feature    order(739780..739782,739858..739860,740158..740172,
                     740548..740550)
                     /gene="thrC"
                     /locus_tag="COSY_0707"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:107206"
     misc_feature    739780..739782
                     /gene="thrC"
                     /locus_tag="COSY_0707"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:107206"
     gene            740680..741567
                     /gene="cysM"
                     /locus_tag="COSY_0708"
                     /db_xref="GeneID:5172675"
     CDS             740680..741567
                     /gene="cysM"
                     /locus_tag="COSY_0708"
                     /EC_number="2.5.1.47"
                     /note="catalyzes the formation of cysteine from
                     3-O-acetyl-L-serine and hydrogen sulfide"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase B"
                     /protein_id="YP_001219544.1"
                     /db_xref="GI:148244850"
                     /db_xref="GeneID:5172675"
                     /translation="MIFKTIEQTIGNTPLVKLQRLNPNSSNIILLKLEGNNPAGSVKD
                     RSVLNMVLNSEKRGEISPGDTLIEATSGNTGIALAMIAAIKNYKMILIMPDYLSQERR
                     DAMSAYGAKLILVTKDEGMEGARDLADKMEKQGIGKQLNQFSNLDNPNAHFNTTAEEI
                     WQDTQGSITHFISAMGTTGTIMGVSDSLKEKNSTIQIIGVQPEDGAQIAGIRRWPKTY
                     LPKIFNLSKVDTIMNISQISAEQTTRNLATIEGIFVGVSSGGSIFSAIELSKKINNAT
                     IVTIACDRGDRYLSTGLFS"
     misc_feature    740692..741561
                     /gene="cysM"
                     /locus_tag="COSY_0708"
                     /note="cysteine synthase B; Region: cysM; TIGR01138"
                     /db_xref="CDD:130208"
     misc_feature    740710..741549
                     /gene="cysM"
                     /locus_tag="COSY_0708"
                     /note="CBS_like: This subgroup includes Cystathionine
                     beta-synthase (CBS) and Cysteine synthase. CBS is a unique
                     heme-containing enzyme that catalyzes a pyridoxal
                     5&apos;-phosphate (PLP)-dependent condensation of serine
                     and homocysteine to give cystathionine; Region: CBS_like;
                     cd01561"
                     /db_xref="CDD:107204"
     misc_feature    order(740722..740730,740767..740769,740785..740787,
                     740791..740793,740917..740919,740926..740928,
                     740974..740979,740986..740991,740998..741003,
                     741163..741168,741418..741426,741430..741438,
                     741505..741507,741535..741537,741544..741546)
                     /gene="cysM"
                     /locus_tag="COSY_0708"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:107204"
     misc_feature    order(740806..740808,740896..740898,741202..741219,
                     741307..741309,741448..741450,741523..741528)
                     /gene="cysM"
                     /locus_tag="COSY_0708"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:107204"
     misc_feature    740806..740808
                     /gene="cysM"
                     /locus_tag="COSY_0708"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:107204"
     gene            741564..742847
                     /locus_tag="COSY_0709"
                     /db_xref="GeneID:5172169"
     CDS             741564..742847
                     /locus_tag="COSY_0709"
                     /note="chloride channel (ClC) family"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="YP_001219545.1"
                     /db_xref="GI:148244851"
                     /db_xref="GeneID:5172169"
                     /translation="MIRYLSHQLPSKLKIYIFLALSSIITIIVIDFFLTYSEHAQNTF
                     KHLISSKPYLSFVITPVVFVLVVYITKYFCHYVQGSGIPQLIIANDSRNKSIRKKLLS
                     FRVATGKIILIFAGMLGGAPIGIEGPSIHIGGSIFFGFNKFIKFKRKLLIHSLIAIGG
                     STGLIIAFNAPIAGFMFSFEEIGRKLKKQALILIAIVSGLVYLLAIIYRGNSIYLSDM
                     SANSIDLILIWQLLPLVILSGIFGGLFSKTTLYLIKIFTAYTKIKVIMIALILGLIIA
                     LFNYLSQGQIAGSGREEVLLILAGYQFDNDFIVMKYLSTLSSLASTIPGGLFMPSISI
                     GAGIGSEMSNYYSQINPQIIIIMSMIAYLTAVIRTPLTCTFVILEMTNTLNLLIPALI
                     VAFIANWISKQISKPPIYEALANNYLKLTQKTKTV"
     misc_feature    741657..742793
                     /locus_tag="COSY_0709"
                     /note="ClC chloride channel family. These protein
                     sequences, closely related to the ClC Eric family, are
                     putative halogen ion (Cl-, Br- and I-) transport proteins
                     found in eubacteria. They belong to the ClC superfamily of
                     chloride ion channels, which share a...; Region:
                     EriC_like; cd01034"
                     /db_xref="CDD:238506"
     misc_feature    741768..742811
                     /locus_tag="COSY_0709"
                     /note="Chloride channel protein EriC [Inorganic ion
                     transport and metabolism]; Region: EriC; COG0038"
                     /db_xref="CDD:223116"
     misc_feature    order(741798..741812,741933..741947,742539..742553,
                     742791..742793)
                     /locus_tag="COSY_0709"
                     /note="putative ion selectivity filter; other site"
                     /db_xref="CDD:238506"
     misc_feature    741939..741941
                     /locus_tag="COSY_0709"
                     /note="putative pore gating glutamate residue; other site"
                     /db_xref="CDD:238506"
     misc_feature    742104..742106
                     /locus_tag="COSY_0709"
                     /note="putative H+/Cl- coupling transport residue; other
                     site"
                     /db_xref="CDD:238506"
     gene            complement(742834..743256)
                     /locus_tag="COSY_0710"
                     /db_xref="GeneID:5172557"
     CDS             complement(742834..743256)
                     /locus_tag="COSY_0710"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219546.1"
                     /db_xref="GI:148244852"
                     /db_xref="GeneID:5172557"
                     /translation="MLWIKAFHIISVITWFASLFYLPRLFVYHSMSQDKLSIDRFKVM
                     EYKLYTGIMMPSFILASVLGLCLSIDGWAYYSIQYWLYVKLLLVMLLIVYHFFCGYLV
                     DVFKADENTRSHVFYRWFNEFPVLILVGVVVLVVVKPF"
     misc_feature    complement(742837..743253)
                     /locus_tag="COSY_0710"
                     /note="Uncharacterized protein family (UPF0093); Region:
                     UPF0093; pfam03653"
                     /db_xref="CDD:217660"
     gene            743870..744829
                     /gene="ftsY"
                     /locus_tag="COSY_0711"
                     /db_xref="GeneID:5172573"
     CDS             743870..744829
                     /gene="ftsY"
                     /locus_tag="COSY_0711"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division transporter substrate-binding
                     protein FtsY"
                     /protein_id="YP_001219547.1"
                     /db_xref="GI:148244853"
                     /db_xref="GeneID:5172573"
                     /translation="MFNFLKKNRSKSENLGTNKPTSLKQRLDKSRQKLGYSLSSLLLG
                     KKEINENLLEELETLLITADVGINTTDKIIKSTRKNASRKTLKNAESLYQFLKDELAK
                     LFIENNQLNISINETFVILVVGVNGAGKTTLIGKLAKSFQNQGKSVMLAAGDTFRAAA
                     IEQLKIWGQRNNIPVVAKTLGADTASVIFDAYQSAQAKNIDILLADTAGRLHTQDNLM
                     QELAKIKRVITKQNINAPHETMLVIDGGSGQNIINQAKEFNKAVNLSGISITKLDGTA
                     KGGGLFSIADELNLPIRYIGIGEGIDDLKIFQPKEFINALFDQ"
     misc_feature    743870..744823
                     /gene="ftsY"
                     /locus_tag="COSY_0711"
                     /note="signal recognition particle-docking protein FtsY;
                     Provisional; Region: PRK10416"
                     /db_xref="CDD:236686"
     misc_feature    <744056..744169
                     /gene="ftsY"
                     /locus_tag="COSY_0711"
                     /note="SRP54-type protein, helical bundle domain; Region:
                     SRP54_N; pfam02881"
                     /db_xref="CDD:217266"
     misc_feature    744221..744757
                     /gene="ftsY"
                     /locus_tag="COSY_0711"
                     /note="The signal recognition particle (SRP) mediates the
                     transport to or across the plasma membrane in bacteria and
                     the endoplasmic reticulum in eukaryotes. SRP recognizes
                     N-terminal sighnal sequences of newly synthesized
                     polypeptides at the ribosome. The...; Region: SRP;
                     cd03115"
                     /db_xref="CDD:239389"
     misc_feature    744239..744262
                     /gene="ftsY"
                     /locus_tag="COSY_0711"
                     /note="P loop; other site"
                     /db_xref="CDD:239389"
     misc_feature    order(744329..744331,744494..744496,744677..744679,
                     744686..744691)
                     /gene="ftsY"
                     /locus_tag="COSY_0711"
                     /note="GTP binding site [chemical binding]; other site"
                     /db_xref="CDD:239389"
     gene            complement(745572..746486)
                     /gene="hemC"
                     /locus_tag="COSY_0712"
                     /db_xref="GeneID:5171942"
     CDS             complement(745572..746486)
                     /gene="hemC"
                     /locus_tag="COSY_0712"
                     /EC_number="2.5.1.61"
                     /note="transformation of porphobilinogen to
                     hydroxymethylbilane in porphyrin biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen deaminase"
                     /protein_id="YP_001219548.1"
                     /db_xref="GI:148244854"
                     /db_xref="GeneID:5171942"
                     /translation="MNKTLKIATRQSPLALWQAQHVKSRLEKIYPNLTVILVKITTKG
                     DQILNSSLSKIGGKGLFIKELEISIMKGMSDIAVHSMKDVPYEIPQEFELGAILKCEN
                     PFDAFVSNHFSSIDDLPKNAKVGTCSMRRILQLKVIRPDLQIIDLRGNVNTRLKKLDD
                     GEFDAIILACAGLIRLGFGNRIKQQIPENQNLPAVGQGAIGIEIRENDKEILDLIKPL
                     IDIETSYRIIAERAMNTQLEGGCSVPVAGFATINNKQITLTGLVGNIDTGVILKEKIF
                     GHVSQAEILGIELANKLILLGAKDILKD"
     misc_feature    complement(745605..746486)
                     /gene="hemC"
                     /locus_tag="COSY_0712"
                     /note="porphobilinogen deaminase; Reviewed; Region: hemC;
                     PRK00072"
                     /db_xref="CDD:234612"
     misc_feature    complement(745605..746474)
                     /gene="hemC"
                     /locus_tag="COSY_0712"
                     /note="Hydroxymethylbilane synthase (HMBS), also known as
                     porphobilinogen deaminase (PBGD), is an intermediate
                     enzyme in the biosynthetic pathway of tetrapyrrolic ring
                     systems, such as heme, chlorophylls, and vitamin B12.
                     HMBS catalyzes the conversion of...; Region: HMBS;
                     cd00494"
                     /db_xref="CDD:238276"
     misc_feature    complement(order(745671..745673,745677..745679,
                     745686..745688,745695..745697,745710..745712,
                     745746..745748,745752..745754,745764..745766,
                     745785..745787,745794..745799,745809..745811,
                     745818..745820,745839..745841,745893..745916,
                     745962..745967,745974..745976,746037..746039,
                     746076..746078,746088..746093,746097..746099,
                     746172..746189,746193..746198,746223..746225,
                     746229..746246,746436..746438,746451..746453))
                     /gene="hemC"
                     /locus_tag="COSY_0712"
                     /note="domain interfaces; other site"
                     /db_xref="CDD:238276"
     misc_feature    complement(order(745764..745766,745893..745898,
                     745905..745907,745962..745964,745971..745973,
                     745980..745988,746025..746027,746046..746048,
                     746094..746099,746103..746111,746238..746243,
                     746247..746249,746433..746435,746445..746447))
                     /gene="hemC"
                     /locus_tag="COSY_0712"
                     /note="active site"
                     /db_xref="CDD:238276"
     gene            746485..746883
                     /locus_tag="COSY_0713"
                     /db_xref="GeneID:5172234"
     CDS             746485..746883
                     /locus_tag="COSY_0713"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219549.1"
                     /db_xref="GI:148244855"
                     /db_xref="GeneID:5172234"
                     /translation="MVKRVYIKIAICFISYLLLLVFISNFSVSQDLTENLLKDAQLVR
                     KDKTNTLIKSSLHNNRYYPEIKQKVITPINKLGEHKNNTIILHVNTNTLKNIKDSNNK
                     NTNQNRINSYPTVFFIDKFSTNLYKIVKHI"
     gene            746962..748404
                     /gene="argH"
                     /locus_tag="COSY_0714"
                     /db_xref="GeneID:5172737"
     CDS             746962..748404
                     /gene="argH"
                     /locus_tag="COSY_0714"
                     /EC_number="4.3.2.1"
                     /note="catalyzes the formation of arginine from
                     (N-L-arginino)succinate"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="YP_001219550.1"
                     /db_xref="GI:148244856"
                     /db_xref="GeneID:5172737"
                     /translation="MNNKTQQKQHTVVPKKKSRQITQTNQSWGGRFKEPTDEFVKIFS
                     ASIFFDKILAPYDIQGSIAHATMLQEVGLLTKYEKNQIIKGLDKILNKIKTGEFEWSV
                     TLEDVHMNIEAYLIKLIGDTGKKLHTGRSRNDQIATDIRLYLRDQVDDIIRKIKRLQL
                     VLTNLAEREMSTIMPGFTHLQAAQPISFGHHMMAYFEMLARDVERLFDCRKRINSMPL
                     GSAALAGTTYPIKRTRTAELLGFKRICLNSLDGVSDRDFAIEFLSIASIIMMHLSRFS
                     EELILWSSTQFNFIELHDSFCTGSSIMPQKKNPDIPELVRGKTGRVYGNLTSLLTIMK
                     SQPLAYNKDNQEDKEPLFDTVDTLKACLRVFADMIPTIQIKCDNMYNSTKQGYTTATD
                     LADYLVNKGLPFRDAHTVVGKSVSYGIKHQKDLSELSLKELQIFDSRIENDVFKVLSL
                     KGSLNARNHLGATSPNQVKQTIKIARKGLK"
     misc_feature    747025..748401
                     /gene="argH"
                     /locus_tag="COSY_0714"
                     /note="argininosuccinate lyase; Provisional; Region:
                     PRK00855"
                     /db_xref="CDD:179143"
     misc_feature    747097..748398
                     /gene="argH"
                     /locus_tag="COSY_0714"
                     /note="Argininosuccinate lyase (argininosuccinase, ASAL);
                     Region: Argininosuccinate_lyase; cd01359"
                     /db_xref="CDD:176463"
     misc_feature    order(747097..747099,747109..747111,747277..747279,
                     747283..747285,747352..747360,747367..747369,
                     747493..747498,747724..747726,747853..747855,
                     747859..747861,747883..747885,747889..747891,
                     747898..747900,747979..747981,747985..747987,
                     747994..747996,748000..748005)
                     /gene="argH"
                     /locus_tag="COSY_0714"
                     /note="active sites [active]"
                     /db_xref="CDD:176463"
     misc_feature    order(747322..747324,747331..747333,747340..747345,
                     747490..747513,747529..747531,747541..747546,
                     747562..747564,747571..747576,747583..747585,
                     747595..747597,747628..747642,747646..747648,
                     747655..747657,747697..747711,747718..747723,
                     747727..747729,747739..747741,747748..747750,
                     747760..747762,747769..747774,747778..747783,
                     747790..747795,747808..747813,747820..747822,
                     747844..747846,747862..747873,747877..747885,
                     747889..747891,747898..747903,747907..747924,
                     747928..747936,747943..747945,747949..747957,
                     747979..747990,747997..747999,748006..748008,
                     748039..748041,748048..748050,748129..748131,
                     748144..748146,748171..748176,748183..748185,
                     748192..748194,748330..748332,748336..748350,
                     748372..748374)
                     /gene="argH"
                     /locus_tag="COSY_0714"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176463"
     gene            748404..749372
                     /gene="fmt"
                     /locus_tag="COSY_0715"
                     /db_xref="GeneID:5172158"
     CDS             748404..749372
                     /gene="fmt"
                     /locus_tag="COSY_0715"
                     /EC_number="2.1.2.9"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="YP_001219551.1"
                     /db_xref="GI:148244857"
                     /db_xref="GeneID:5172158"
                     /translation="MHSKSTSFKTRIAFAGTTKFSVAILEILINAKYDIVGVYCQPDR
                     PKGRGRILTACPVKEKALEYNLKIFQPENLQSTKTQQALAKLNADVMIVVSYGQILPE
                     RILNMLKYGCLNIHSSLLPRWRGAAPIQRAILAGDKITGISIIQMNKILDTGDILLEK
                     NCTITLNDTTQSLHNKLVKLGSNAIVEVLNNLDNLSPTEQSKNNITYAKKLKKNEAWI
                     DWTQSAIQIHQKIRAFNPYPITQTHASSNRFATKILRIFSASIVVTNDNYSPGNIIKH
                     NKKICIVATGDGALSLETVQLSGKKVLNIKDFSNAYKLTKLFITCR"
     misc_feature    748434..749351
                     /gene="fmt"
                     /locus_tag="COSY_0715"
                     /note="methionyl-tRNA formyltransferase; Reviewed; Region:
                     fmt; PRK00005"
                     /db_xref="CDD:234567"
     misc_feature    748434..749036
                     /gene="fmt"
                     /locus_tag="COSY_0715"
                     /note="Methionyl-tRNA formyltransferase, N-terminal
                     hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N;
                     cd08646"
                     /db_xref="CDD:187715"
     misc_feature    order(748449..748451,748461..748466,748680..748703,
                     748716..748718,748743..748754,748776..748778,
                     748836..748838,748842..748847,748854..748859)
                     /gene="fmt"
                     /locus_tag="COSY_0715"
                     /note="putative active site [active]"
                     /db_xref="CDD:187715"
     misc_feature    order(748452..748457,748461..748463,748524..748526,
                     748536..748538,748542..748553,748683..748694,
                     748743..748745,748749..748754,748776..748784,
                     749031..749033)
                     /gene="fmt"
                     /locus_tag="COSY_0715"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187715"
     misc_feature    order(748680..748682,748689..748691,748695..748703,
                     748716..748718,748743..748745,748842..748847,
                     748854..748859)
                     /gene="fmt"
                     /locus_tag="COSY_0715"
                     /note="putative cosubstrate binding site; other site"
                     /db_xref="CDD:187715"
     misc_feature    order(748743..748745,748749..748751,748857..748859)
                     /gene="fmt"
                     /locus_tag="COSY_0715"
                     /note="catalytic site [active]"
                     /db_xref="CDD:187715"
     misc_feature    749046..749318
                     /gene="fmt"
                     /locus_tag="COSY_0715"
                     /note="C-terminal domain of Formyltransferase and other
                     enzymes; Region: Met_tRNA_FMT_C; cd08704"
                     /db_xref="CDD:187732"
     misc_feature    order(749112..749114,749160..749162,749166..749168,
                     749289..749291,749295..749297,749301..749306,
                     749310..749312)
                     /gene="fmt"
                     /locus_tag="COSY_0715"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187732"
     gene            749621..752179
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /db_xref="GeneID:5171954"
     CDS             749621..752179
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpB"
                     /protein_id="YP_001219552.1"
                     /db_xref="GI:148244858"
                     /db_xref="GeneID:5171954"
                     /translation="MNFDKLTAQFQQDLSTAQSIAITKNHSTIEAVHIISSMLQNNNS
                     SVNNLLSNIDIDIHQLKQETDKEINTLATISNPSGDVNISQNLLRLLNQMEKLALNKK
                     DSYLSTEIFLLAIIKGNDTTTKLLKAHGVNEINLNQAIDNLRGGKNVNNQNTENNQNT
                     LNKYTQDLTQLAIDGKLDPVIGRDSEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINHEVSEGIKGKRVLSLDMTALIAGAKYRGEFEERLKVVLKELEDKQGQIILF
                     IDELHTMVGIGKSDGSMDAGNILKPALARGDLHCIGATTLNEYRQYIEKDSALERRFQ
                     KVLVDEPTEQDTIAILRGLKEKYEVHHGVEITDPAIIVAVTYSTRYITDRQLPDKAID
                     LIDEAASQIRMEIDSKPESMDKLDRKLVQLKIERMALKKEKDKASKTRLEELVKLIKS
                     LEKEYANLEKIWKKEKLVVQSAHHLKEELEQAKSDLENAHRNNNLAKMSELQYGIIPE
                     LEQKINMAENADTEQMTLLRNKVTENEIAHIVARWTGIPVDKMMAGEKDKLLQMETII
                     HKRLVGQDKAVKVISDAVRRARSGLSDPNRPDGSFLFMGPTGVGKTELTKALADFLFD
                     TEQAIVRIDMSEFMEKHSVARLIGAPPGYVGYEQGGVLTEAVRRKPYSIILLDEIEKA
                     HSDLFNILLQVLDDGRLTDSQGRTVDFKNTIIIMTSNLGSHLIQQNPGKDMSVELTKI
                     VSEHFRPEFVNRIDEIVTFKTLEKSQIKGIALRQIEILSSRLSKLNLRITLSDIAISM
                     IVNKGYNPVFGARPLKRTIQQLLENPLSKKIIAGEFLSDSTIHGDVKDGKIVFY"
     misc_feature    749636..752173
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="ATP-dependent chaperone ClpB; Region:
                     chaperone_ClpB; TIGR03346"
                     /db_xref="CDD:234173"
     misc_feature    749903..750055
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="Clp amino terminal domain; Region: Clp_N;
                     pfam02861"
                     /db_xref="CDD:217254"
     misc_feature    750161..750643
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    750236..750259
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(750239..750262,750452..750454,750563..750565)
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    750440..750457
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    750614..750616
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    751331..751897
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    751433..751456
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(751436..751459,751649..751651,751775..751777)
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    751637..751654
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    751874..751876
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    751904..752143
                     /gene="clpB"
                     /locus_tag="COSY_0716"
                     /note="C-terminal, D2-small domain, of ClpB protein;
                     Region: ClpB_D2-small; pfam10431"
                     /db_xref="CDD:204486"
     gene            752249..752890
                     /gene="rnfE"
                     /locus_tag="COSY_0717"
                     /db_xref="GeneID:5172111"
     CDS             752249..752890
                     /gene="rnfE"
                     /locus_tag="COSY_0717"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex protein RnfE"
                     /protein_id="YP_001219553.1"
                     /db_xref="GI:148244859"
                     /db_xref="GeneID:5172111"
                     /translation="MCNYNKIIKNGLWNNNQALVAILGLCPLLAVTNNIVNAVGLGLA
                     TTFVLVMSNVTVSIFRHHISKEIRIPVFVLLIASFVTIVELIMQSYFYDLYLILGIFV
                     PLIVTNCAILGRAEAFASKNTWDKSILDGLMMGIGFSVVLIILGAMRELIGNGTLFDK
                     SVLLLGDFGNTLSITVFENYQGTLLAILPPGAFIGLGLIIAMKNKYDLKRKKL"
     misc_feature    752249..752884
                     /gene="rnfE"
                     /locus_tag="COSY_0717"
                     /note="electron transport complex RsxE subunit;
                     Provisional; Region: PRK12405"
                     /db_xref="CDD:237091"
     gene            753135..753947
                     /gene="hemK"
                     /locus_tag="COSY_0718"
                     /db_xref="GeneID:5172531"
     CDS             753135..753947
                     /gene="hemK"
                     /locus_tag="COSY_0718"
                     /codon_start=1
                     /transl_table=11
                     /product="protein methyltransferase HemK"
                     /protein_id="YP_001219554.1"
                     /db_xref="GI:148244860"
                     /db_xref="GeneID:5172531"
                     /translation="MTIINLQTLDTIQNYLSSDIIDIVLLLSLTLDKSHAQLISHNNY
                     QLSSNEKNQLNQFIKHRQSGVPFAYLSGTKGFYHLDFKVTPDTLIPRPETELLIDIAL
                     GLFNQNQTYEVLDLGTGSGVIAITISDKNPNWNLTATDFSINALAVAKQNTKTNINFQ
                     LGSWFEATPNQTFDLIISNPPYIKQNDIHLNELRFEPQSALISGKDGLDDIQIIINNI
                     PKFLNEKGYLLLEHGFNQQQKIIQLLKDNFFNIKKFKDYNQKNRAILAQIKH"
     misc_feature    753231..753935
                     /gene="hemK"
                     /locus_tag="COSY_0718"
                     /note="N5-glutamine S-adenosyl-L-methionine-dependent
                     methyltransferase; Provisional; Region: PRK09328"
                     /db_xref="CDD:236467"
     misc_feature    753471..>753680
                     /gene="hemK"
                     /locus_tag="COSY_0718"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(753480..753500,753552..753557,753618..753626,
                     753669..753671)
                     /gene="hemK"
                     /locus_tag="COSY_0718"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(754588..756078)
                     /gene="fumB"
                     /locus_tag="COSY_0719"
                     /db_xref="GeneID:5172413"
     CDS             complement(754588..756078)
                     /gene="fumB"
                     /locus_tag="COSY_0719"
                     /EC_number="4.2.1.2"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase, class I"
                     /protein_id="YP_001219555.1"
                     /db_xref="GI:148244861"
                     /db_xref="GeneID:5172413"
                     /translation="MKIQQKHVIESIFNALQYISYYHSPDFIQAMTSAYEKETHKAAK
                     NAITQILINSKMAVFGKRPICQDTGVVNVFVEVGMEVTWIANLSLEDMINEGVRQAFT
                     YVNNPLRASIVKDPLFTRVNTKDNTPAVIHMKVVKGEQLNFIVAAKGGGSENKAKFSM
                     LEPDVDIIDWVLEAIPTMGAGWCPPGIIGIGVGGTAEKSMLMAKQSLMEPIDIKDIAQ
                     KSNPSNLEKLRLELFDKINDLGIGAQGLGGLTTVLDVKIKDYPTHAASQAVAMIPNCA
                     ATRHLHFSLDGSGVAQLPQVDMDSYPQLEMDYTQYKKIDLSNLTREKMALWHIGDTLL
                     LSGSIITGRDVAHKYLKEMIDNGEGLPDGVNFDNKFIYYVGPVDAVGDEVIGPSGPTT
                     ATRMDKFTDMILDNTNILGMIGKAERGEDSVQIIKKHKVTYLIAVGGAAYLISKSIKK
                     AKKIAFKEMGMEAIYEFEVKDMPVTVAVDTQGNNIHSIFKDIKIIH"
     misc_feature    complement(755224..756057)
                     /gene="fumB"
                     /locus_tag="COSY_0719"
                     /note="Fumarate hydratase (Fumerase); Region: Fumerase;
                     pfam05681"
                     /db_xref="CDD:218689"
     misc_feature    complement(754612..755220)
                     /gene="fumB"
                     /locus_tag="COSY_0719"
                     /note="Fumarase C-terminus; Region: Fumerase_C; pfam05683"
                     /db_xref="CDD:218690"
     gene            756158..757237
                     /gene="mreB"
                     /locus_tag="COSY_0720"
                     /db_xref="GeneID:5172239"
     CDS             756158..757237
                     /gene="mreB"
                     /locus_tag="COSY_0720"
                     /note="functions in MreBCD complex in some organisms"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="YP_001219556.1"
                     /db_xref="GI:148244862"
                     /db_xref="GeneID:5172239"
                     /translation="MFNFLKGQSLDFLKGQSLDFLKGQSLSIDLGTANTLICMDGAVV
                     LNEPSVVAIHNDRRSLESTVIAVGQDAKNMLGRTPGSIEAIRPMKDGVIADFKITEKM
                     LQHFIRKVLRSGFFSPSPKVLICVPCGATQVERRAIKESAVGAGARDVYLIEEPMAAA
                     LGAGMAIEEASGAMVIDIGGGTTEIAIMSLNGIVYSDSLRIGGDVFDDTIVKFIRREH
                     GIIIGYSTAEKIKEEVGSAFKSSAVKEMQFRGRDVAKGIPVSFNITNTEILQTLKEPL
                     KIIIGSIKTALEKTPPELSSDIAENGLVLTGGGALLDGLNKLISQETNLPVRIADDPL
                     TCVARGGGVALNMISKHNIGFLAAE"
     misc_feature    756233..757210
                     /gene="mreB"
                     /locus_tag="COSY_0720"
                     /note="rod shape-determining protein MreB; Provisional;
                     Region: PRK13927"
                     /db_xref="CDD:237562"
     misc_feature    756233..757201
                     /gene="mreB"
                     /locus_tag="COSY_0720"
                     /note="MreB and similar proteins; Region: MreB_like;
                     cd10225"
                     /db_xref="CDD:212668"
     misc_feature    order(756242..756244,756248..756259,756428..756430,
                     756620..756622,756686..756688,756692..756703,
                     756764..756769,756839..756841,756848..756853,
                     757076..757084,757088..757093,757157..757159,
                     757166..757168)
                     /gene="mreB"
                     /locus_tag="COSY_0720"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212668"
     misc_feature    order(756242..756244,756686..756688)
                     /gene="mreB"
                     /locus_tag="COSY_0720"
                     /note="Mg binding site [ion binding]; other site"
                     /db_xref="CDD:212668"
     misc_feature    order(756317..756319,756377..756379,756401..756403,
                     756665..756667,756671..756673,756731..756733,
                     756827..756829,756833..756835,756902..756904,
                     756926..756928,756935..756937,757025..757027,
                     757034..757036,757130..757132)
                     /gene="mreB"
                     /locus_tag="COSY_0720"
                     /note="putative protofilament interaction site
                     [polypeptide binding]; other site"
                     /db_xref="CDD:212668"
     misc_feature    order(756647..756652,756674..756676,757052..757060,
                     757133..757135,757139..757141,757148..757150)
                     /gene="mreB"
                     /locus_tag="COSY_0720"
                     /note="RodZ interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:212668"
     gene            757274..758068
                     /gene="mreC"
                     /locus_tag="COSY_0721"
                     /db_xref="GeneID:5172049"
     CDS             757274..758068
                     /gene="mreC"
                     /locus_tag="COSY_0721"
                     /note="in some organisms this protein is a transmembrane
                     protein while in others it is periplasmic; involved in
                     some organisms with other components of the MreBCD complex
                     and with penicillin binding proteins in the periplasm or
                     cell wall"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="YP_001219557.1"
                     /db_xref="GI:148244863"
                     /db_xref="GeneID:5172049"
                     /translation="MKFLELFIPVIISILLILSDYKFSYLNHLRQSIETLISPIYMVV
                     NLPSQIYIWIDKQGTSKDQLTINNDNLHRELLKLKAKLQTYNALALENKKLQALLGSS
                     YTVKQQNFTLARISELSQSRIKKQIIINKGSSSGIKIGQIALSSKGIIGQISRTTPLY
                     STILMASDPTQHVPVKNERSGVRGISKGIANNNHLLSVEFIEPNLDVKVGDVFLSSAI
                     GSKFPDGYPVGTVISVEKNQNEPFLHIQLKPAQIPEQLEFVIITTD"
     misc_feature    757280..758056
                     /gene="mreC"
                     /locus_tag="COSY_0721"
                     /note="rod shape-determining protein MreC; Provisional;
                     Region: PRK13922"
                     /db_xref="CDD:237560"
     misc_feature    757700..758056
                     /gene="mreC"
                     /locus_tag="COSY_0721"
                     /note="rod shape-determining protein MreC; Region: MreC;
                     pfam04085"
                     /db_xref="CDD:217883"
     gene            758071..758541
                     /gene="mreD"
                     /locus_tag="COSY_0722"
                     /db_xref="GeneID:5172047"
     CDS             758071..758541
                     /gene="mreD"
                     /locus_tag="COSY_0722"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="YP_001219558.1"
                     /db_xref="GI:148244864"
                     /db_xref="GeneID:5172047"
                     /translation="MNVQRRPYIFLMKITFFALILSVIPLNKLLLGASAFWLLLLYIY
                     WIVYFSTKLKFFIALILGTLVDILHGDILGQNALALIFSSLFISNIKQSFFLSNLSTQ
                     QVYIFISSSIYLVFFLLIFVLTQGFIINYYLFLAPFTSAFIWPVVQFLLSKCKA"
     gene            758499..760379
                     /gene="mrdA"
                     /locus_tag="COSY_0723"
                     /db_xref="GeneID:5172045"
     CDS             758499..760379
                     /gene="mrdA"
                     /locus_tag="COSY_0723"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="YP_001219559.1"
                     /db_xref="GI:148244865"
                     /db_xref="GeneID:5172045"
                     /translation="MASRSVLIIKMQSINNVQFENKTLFSRLRLALIFIFLLTTLLII
                     RIYNLQIVNHQYYLKKSLDNQIRTMPITPSRGKIFDRNGNVLATNKLAFRLTLTQEKT
                     KNITKTLQQLKQSGFINDKDIKSFNQNIKHYQKFHSIPIRYNLNEIQVAKFLISNIFI
                     GVNIEPYFHRIYPNQNSSVHVIGYVSRMSKKDQLIYDKKNYLGTLFVGKTGIEKQYEI
                     LLHGTNGLQQIERNVNGRVIHTKIIKPAITGKNLYLSIDLDMQKKAETLLKGKRGSIV
                     VIDVKNGEILTLVSTPIYNPNWFVNGISHTNYNQLQTSKNIPQLNRAIQGLYPPGSTI
                     KPMVALAGLEEGVITNISSTFCPGYYKLPNVKRKFNDWKKTGHGHVNVKDSITQSCDV
                     FFYDLANKLGIDKLHNNLDLFNFGRKTNIDIPGENPGILPSKVWKKINKHKPWYRGET
                     LITGIGQGFIAVTPLQLAVATTAIANKGILFQPTLLKNTQASDDIIIESKKDSHIQIP
                     IKNIQNWEDVIDGMKQAIYAPKGTARKLNKGLTYTLAGKTGTAQVFSLDNTIKQYIEA
                     KLDERLRDHALFTGFAPTENPEIAIAIIVENAGNGSSKAAPIARQVLDVYFNKQLNNT
                     LP"
     misc_feature    758637..760355
                     /gene="mrdA"
                     /locus_tag="COSY_0723"
                     /note="penicillin-binding protein 2; Region: pbp2_mrdA;
                     TIGR03423"
                     /db_xref="CDD:234204"
     misc_feature    758709..759224
                     /gene="mrdA"
                     /locus_tag="COSY_0723"
                     /note="Penicillin-binding Protein dimerisation domain;
                     Region: PBP_dimer; pfam03717"
                     /db_xref="CDD:217689"
     misc_feature    759315..760340
                     /gene="mrdA"
                     /locus_tag="COSY_0723"
                     /note="Penicillin binding protein transpeptidase domain;
                     Region: Transpeptidase; pfam00905"
                     /db_xref="CDD:216183"
     gene            complement(760686..761798)
                     /gene="tgt"
                     /locus_tag="COSY_0724"
                     /db_xref="GeneID:5172051"
     CDS             complement(760686..761798)
                     /gene="tgt"
                     /locus_tag="COSY_0724"
                     /EC_number="2.4.2.29"
                     /codon_start=1
                     /transl_table=11
                     /product="queuine tRNA-ribosyltransferase"
                     /protein_id="YP_001219560.1"
                     /db_xref="GI:148244866"
                     /db_xref="GeneID:5172051"
                     /translation="MKFELKNTNYLARRGKIIFDRGEVETPSFMPVGTYGSVKAMTPE
                     ELSSFGTQMILGNSFHLAITPGIDVVQAHGNLHDFMHWKGPILTDSGGFQVFSLGETR
                     KISEKGVDFRSPKDGAKIFMGPEESIQIQKKLGSDIVMIFDECTPYPADKKTVYKSMQ
                     LSLRWAQRSKNEHDRLNNKNALFGIVQGGMHEDLRIQSAATLVEIGFNGFAIGGLSVG
                     ESKEEMIKVLDYLPSQLPSDKLRYLMGVGTPKDLVEAVERGIDMFDCVMPTRNARNGY
                     LFTSIGIVKIRNARYRLDTSVLDECCHCYTCQNYSKSYLHHLQRKNEILGARLNTIHN
                     LYYYQYLMLQMRRAIESNKFSKFKKEFYQQQGHDTL"
     misc_feature    complement(760752..761798)
                     /gene="tgt"
                     /locus_tag="COSY_0724"
                     /note="queuine tRNA-ribosyltransferase; Provisional;
                     Region: tgt; PRK00112"
                     /db_xref="CDD:234642"
     misc_feature    complement(760752..761792)
                     /gene="tgt"
                     /locus_tag="COSY_0724"
                     /note="Queuine/archaeosine tRNA-ribosyltransferase
                     [Translation, ribosomal structure and biogenesis]; Region:
                     Tgt; COG0343"
                     /db_xref="CDD:223420"
     gene            complement(761788..763581)
                     /locus_tag="COSY_0725"
                     /db_xref="GeneID:5172272"
     CDS             complement(761788..763581)
                     /locus_tag="COSY_0725"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="YP_001219561.1"
                     /db_xref="GI:148244867"
                     /db_xref="GeneID:5172272"
                     /translation="MCSTDKQTKAYDFKTRDIKVLKKLFPYLLKMRIRVILAMLFLIV
                     AKFANVAVPVVLKEIVDVLNQTNVLLILPLGLLFAYGALRLTSSLFNELRDAIFVRVR
                     YHIMRLIAVSVFKHLHTLDLSFHLDRRIGGITRDVDRGTQSVSTLLSIFVFNIIPAFF
                     EICLVIGVLWFNYDIFFAGISLLTVVFYVGFTLVITTWRMKYRYQMNDMQSEANMNAV
                     DSLINYETVKYFNQEDAEVNRYDETMTRWENIATKSFTSMTALNFVQSAVIAVGITII
                     LIFASQGVVDESLSLGDMIMIQVLLLQLFMPLGSLGIVYRQIKHNFIDMNNMFDLLDR
                     QSKVNSSKDAPKIKIGQGKIEFKRISFAYKGKNKILKEVSFVIEPGQKVAIVGKSGSG
                     KSTLAKLLFRFYDVDSGEILIDGQNIQTLNQHSVQSVIGVVPQDTVMFNESIYYNIAY
                     GKQDTNQHEVEKVAKLSFIDTFINKLPQGYDTLVGERGLKLSGGEKQRLAIARVLLKN
                     PPILIFDEATSALDSYSEKMVQKSLKILSSKHTILVIAHRLSTIIDSNKIIVLGDGKV
                     QESGTHAKLLESNGEYAKLWQLQVNEKSDEI"
     misc_feature    complement(762658..763479)
                     /locus_tag="COSY_0725"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:216049"
     misc_feature    complement(761821..763305)
                     /locus_tag="COSY_0725"
                     /note="ABC-type transport system involved in Fe-S cluster
                     assembly, permease and ATPase components
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: ATM1; COG5265"
                     /db_xref="CDD:227590"
     misc_feature    complement(761815..762522)
                     /locus_tag="COSY_0725"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    complement(762400..762423)
                     /locus_tag="COSY_0725"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(761941..761943,762034..762039,
                     762277..762279,762397..762405,762409..762414))
                     /locus_tag="COSY_0725"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(762277..762288)
                     /locus_tag="COSY_0725"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(762082..762111)
                     /locus_tag="COSY_0725"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(762034..762051)
                     /locus_tag="COSY_0725"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(762016..762027)
                     /locus_tag="COSY_0725"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(761935..761955)
                     /locus_tag="COSY_0725"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            764042..765091
                     /gene="ribD"
                     /locus_tag="COSY_0726"
                     /db_xref="GeneID:5172682"
     CDS             764042..765091
                     /gene="ribD"
                     /locus_tag="COSY_0726"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /note="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     (riboflavin-specific deaminase) /
                     5-amino-6-(5-phosphoribosylamino)uracil reductase."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin biosynthesis protein
                     RibD"
                     /protein_id="YP_001219562.1"
                     /db_xref="GI:148244868"
                     /db_xref="GeneID:5172682"
                     /translation="MLTTFSKNETQNMTIAIKLALQGRYGVKSNPMVGCVIVKHSKII
                     AKGYHESFGQAHGEINALQQINYKAHGATLYVTLEPCSHQGKTPSCAQAIINSGVKKV
                     IIAMLDPNPLVNGKGVVMLKYAGIEVKIGLLKNDASILNQGFIKRMQTNQPFIRCKVA
                     MSIDGKTSMSSGESKWITSKVARLDVQKLRANHQAIITGSGTIINDNPLMTVRLDGVN
                     SKPLRVVIDSKNQITDTSLNIFNTDAPTLILNPDNTKVLASGKLDLSNVLTQLGNQGI
                     NNVLLEAGPKLIGAMIKINLIDEFIIYMAPILMGSDANSILNLVIKDMSYKIKLDIVD
                     VRMVGDNIKITATLK"
     misc_feature    764078..765076
                     /gene="ribD"
                     /locus_tag="COSY_0726"
                     /note="riboflavin biosynthesis protein RibD; Region:
                     eubact_ribD; TIGR00326"
                     /db_xref="CDD:232920"
     misc_feature    764078..764416
                     /gene="ribD"
                     /locus_tag="COSY_0726"
                     /note="Riboflavin-specific deaminase. Riboflavin
                     biosynthesis protein RibD
                     (Diaminohydroxyphosphoribosylaminopyrimidine deaminase)
                     catalyzes the deamination of
                     2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone
                     5&apos;-phosphate, which is an intermediate step in
                     the...; Region: Riboflavin_deaminase-reductase; cd01284"
                     /db_xref="CDD:238611"
     misc_feature    order(764207..764215,764279..764284,764309..764311)
                     /gene="ribD"
                     /locus_tag="COSY_0726"
                     /note="catalytic motif [active]"
                     /db_xref="CDD:238611"
     misc_feature    order(764207..764209,764213..764215,764282..764284,
                     764309..764311)
                     /gene="ribD"
                     /locus_tag="COSY_0726"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:238611"
     misc_feature    764498..765085
                     /gene="ribD"
                     /locus_tag="COSY_0726"
                     /note="RibD C-terminal domain; Region: RibD_C; cl17279"
                     /db_xref="CDD:247833"
     gene            765088..766281
                     /gene="dfp"
                     /locus_tag="COSY_0727"
                     /db_xref="GeneID:5172443"
     CDS             765088..766281
                     /gene="dfp"
                     /locus_tag="COSY_0727"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /note="bifunctional phosphopantothenoylcysteine
                     decarboxylase / phosphopantothenate-cysteine ligase."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/pantothenate metabolism flavoprotein"
                     /protein_id="YP_001219563.1"
                     /db_xref="GI:148244869"
                     /db_xref="GeneID:5172443"
                     /translation="MNNLTNKHIIIGVSGSISAYKAPDIVRRLQDFDAKVKVILTKGG
                     AKFITKWSLQSISKNKVYHNLWDEDAEFGMRHIELARWADAILIAPASANTITNISIG
                     KANDLLSSVVLASDALLFIAPAMNLKMYQSHALQNNLSILINRHAIIIKPGSGEQVCG
                     DIGMGKLAEPSSIAKQVFQQFISTKLTGKKVLITLGSTIEAIDPIRFISNHSSGKMGM
                     ELVNTCIESGALVTCIYGNITTTLNTKSNNISIVNAQQMYDKVMDNITNQDIFIACAA
                     VSDFSAKNTKNQKIKNDRRNLTLELIPNKDILADVCKLKEKPICMGFAAETQNMLKNA
                     KNKLKNKGCDVIILNDVSNANFGFNTDENEVTFLSKNLNKKIAKSSKKKVAKKILEIF
                     IKEYL"
     misc_feature    765088..766194
                     /gene="dfp"
                     /locus_tag="COSY_0727"
                     /note="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate synthase; Validated;
                     Region: PRK05579"
                     /db_xref="CDD:235513"
     misc_feature    765106..765489
                     /gene="dfp"
                     /locus_tag="COSY_0727"
                     /note="Flavoprotein; Region: Flavoprotein; pfam02441"
                     /db_xref="CDD:217035"
     misc_feature    765643..766191
                     /gene="dfp"
                     /locus_tag="COSY_0727"
                     /note="DNA / pantothenate metabolism flavoprotein; Region:
                     DFP; pfam04127"
                     /db_xref="CDD:217913"
     gene            complement(766893..770318)
                     /gene="dnaE"
                     /locus_tag="COSY_0728"
                     /db_xref="GeneID:5172236"
     CDS             complement(766893..770318)
                     /gene="dnaE"
                     /locus_tag="COSY_0728"
                     /EC_number="2.7.7.7"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III alpha subunit"
                     /protein_id="YP_001219564.1"
                     /db_xref="GI:148244870"
                     /db_xref="GeneID:5172236"
                     /translation="MVNPGFVHLHCQSEFSVENSVVRISKFIEKVQEIGMDSIALTDE
                     SNLFAAVKFYQKATAANIKPIFGARINIKDKEGELYSGLLLCQDHQGYLNLSELISLS
                     YTQGRSCERVSITQQELIDYNQGLIMIATPIYSDVAKYLISNKIVKAKQKSEFWQAIF
                     VDRYYLGVQRTSRKFDEKHLHLCIKLALELGIAVVATNDVQFLNESDFDAHEARICIS
                     QGSLLDDTQRKRHFSNQQFLKSPKQMYKLFSDLPEILENTLELAKRCNVHFELFKKNY
                     LPDFPIPEHLTIEQFFSEESEGGLVQRLKNLKVDVNIYQQRLKFELDIIIQMGFSGYF
                     LIVADFIKWSKENDIPVGPGRGSGAGSLVAYVLGITNVDPIKHELLFERFLNPERVSM
                     PDLDIDFCTDRRDEVIGYVAKRYGHEKVSQIITYGTMAAKGVVRDVGRVLGHPYGFSD
                     QISKMIPNDLRATLEKALSEPEKGGSKELRARYDSEESVTALIDLSKQLEGLVRNVGT
                     HAGGVVIAPSKISDFCPVYKGYGENNSVVSQFDKDDVEAVGLVKFDFLGLSNLTVIHK
                     AIKLISVKGLSDEPINLDALPLDDKRVYKLLQSCDTTGVFQLESKGMRSYLKKLQADN
                     FEDIVAMLALYRPGPLDAGMVDDYINVKHGAQVKYPHPMLEQILKPTNGVFLYQEQVM
                     KSAQVMAGYSLGGADLLRRAMGKKKASEMNRQRSVFVKGAAERGINEKKANEIFDLID
                     KFSGYGFNKSHSVAYAYVSYHTAWLKSHYPAPFMAAVLSGVMDDTDRVSFTISEIRQM
                     GLIVNGPNVCESNYEFSILDKNTVLYGLGAIKGVGVALVDAVVFERSTNGTYKDLFEF
                     CSRIEKRYLNKRAIEALIYSGAFDILGVNRESLIKTYPIAIRQAEQKQSDYFSGQNGL
                     FSHNEYETRYLLAPSFSFKKRLQLEKSVLGYYFDNHPTNEYTVADLKNINVVLPSNIV
                     FRKNRDVRVLALISDLRYRSIKNGERIALITIEDGSASLNAVVFTKTLTLVSNQLMTD
                     EVVVISGKINKDFRDQWQLVVNKIENIEQVKISYAKGFEVLLNTKHQSIFDKLIKILI
                     EHKGNCPVKISYIVDNLRGSMLLNKVYLVAPNQQLIDAVNILAQDQVSKVYYH"
     misc_feature    complement(766929..770306)
                     /gene="dnaE"
                     /locus_tag="COSY_0728"
                     /note="DNA polymerase III subunit alpha; Validated;
                     Region: dnaE; PRK05673"
                     /db_xref="CDD:235554"
     misc_feature    complement(769479..770306)
                     /gene="dnaE"
                     /locus_tag="COSY_0728"
                     /note="Polymerase and Histidinol Phosphatase domain of
                     alpha-subunit of bacterial polymerase III DnaE1; Region:
                     PHP_PolIIIA_DnaE1; cd07433"
                     /db_xref="CDD:213988"
     misc_feature    complement(order(769716..769718,769722..769724,
                     770112..770114,770187..770189,770262..770264,
                     770283..770285,770289..770291))
                     /gene="dnaE"
                     /locus_tag="COSY_0728"
                     /note="putative active site [active]"
                     /db_xref="CDD:213988"
     misc_feature    complement(order(769521..769523,770127..770135,
                     770145..770147))
                     /gene="dnaE"
                     /locus_tag="COSY_0728"
                     /note="putative PHP Thumb interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:213988"
     misc_feature    complement(767127..767381)
                     /gene="dnaE"
                     /locus_tag="COSY_0728"
                     /note="DnaE_OBF: A subfamily of OB folds corresponding to
                     the C-terminal OB-fold nucleic acid binding domain of
                     Thermus aquaticus and Escherichia coli type C replicative
                     DNA polymerase III alpha subunit (DnaE). The DNA
                     polymerase holoenzyme of E. coli contains...; Region:
                     DnaE_OBF; cd04485"
                     /db_xref="CDD:239931"
     misc_feature    complement(order(767154..767156,767211..767213,
                     767217..767219,767223..767225,767379..767381))
                     /gene="dnaE"
                     /locus_tag="COSY_0728"
                     /note="generic binding surface II; other site"
                     /db_xref="CDD:239931"
     misc_feature    complement(order(767169..767177,767199..767207,
                     767226..767228,767271..767273,767277..767285,
                     767301..767303,767307..767318,767358..767366))
                     /gene="dnaE"
                     /locus_tag="COSY_0728"
                     /note="generic binding surface I; other site"
                     /db_xref="CDD:239931"
     gene            complement(770460..770777)
                     /locus_tag="COSY_0729"
                     /db_xref="GeneID:5172266"
     CDS             complement(770460..770777)
                     /locus_tag="COSY_0729"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219565.1"
                     /db_xref="GI:148244871"
                     /db_xref="GeneID:5172266"
                     /translation="MKRVLLIVLVLFTLIALAGYMGSLYNWNNNSNSFKSSIAAAETG
                     YKENLAADMAWRDTGKMIKEAKKLYKSGKNVAAIILANKAHKQTVNATLQTILAKTAG
                     PRF"
     gene            complement(770792..771607)
                     /gene="soxA"
                     /locus_tag="COSY_0730"
                     /db_xref="GeneID:5172420"
     CDS             complement(770792..771607)
                     /gene="soxA"
                     /locus_tag="COSY_0730"
                     /note="cytochrome c"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur oxidation protein SoxA"
                     /protein_id="YP_001219566.1"
                     /db_xref="GI:148244872"
                     /db_xref="GeneID:5172420"
                     /translation="MKKIITTMACLGFLVSVALADVKSDQKAFINHFKTIFPSVELAD
                     YTNGVYMIDQDSREQFEEILDGIPPYEEAVEDGGKEYLKFGLNKCVSLKDPVAARIQH
                     PYFNEATQQVVTLETAIKNCYQNQTGNKLSYNKGKIARISAWISDQAAGQKINVKVES
                     FGAKVAYEKGKIFFYAKRGQFNMSCADCHVYNAGKKARADILSPALGHTTHIPMYRVK
                     WTGMGTLHRRYSSCLKNIRANPLKPQTEALRNMEFFHQAMSNGLKITADRYRK"
     gene            complement(771635..771937)
                     /gene="soxZ"
                     /locus_tag="COSY_0731"
                     /db_xref="GeneID:5171932"
     CDS             complement(771635..771937)
                     /gene="soxZ"
                     /locus_tag="COSY_0731"
                     /note="sulfur compound-chelating protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur oxidation protein SoxZ"
                     /protein_id="YP_001219567.1"
                     /db_xref="GI:148244873"
                     /db_xref="GeneID:5171932"
                     /translation="MASIKLKPKAKKGVISIKCLIKHPMETGLRKKKGKIVPANYIEN
                     IVILHNGNKIVDADIGISISKNPYFKFKVPGKKGDIIELKYNSNKGETGSATVKSK"
     misc_feature    complement(771644..771928)
                     /gene="soxZ"
                     /locus_tag="COSY_0731"
                     /note="Sulphur oxidation protein SoxZ; Region: SoxZ;
                     pfam08770"
                     /db_xref="CDD:220011"
     gene            complement(771971..772414)
                     /gene="soxY"
                     /locus_tag="COSY_0732"
                     /db_xref="GeneID:5172000"
     CDS             complement(771971..772414)
                     /gene="soxY"
                     /locus_tag="COSY_0732"
                     /note="sulfur covalently-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur oxidation protein SoxY"
                     /protein_id="YP_001219568.1"
                     /db_xref="GI:148244874"
                     /db_xref="GeneID:5172000"
                     /translation="MKRRLFLKSAIASSAVATAVSAGLLTPSMVFANSASFKDKSDIV
                     STSVVSAKEGLFKFKAPKIAENGEVVPMTVDASKIKDVTDISFYIKNNSMPLAASFNL
                     SGAHGYVSTRVKMGRTSSVIALVTAGGIITSRTQEVKVTIGGCGG"
     misc_feature    complement(771980..772264)
                     /gene="soxY"
                     /locus_tag="COSY_0732"
                     /note="Sulfur oxidation protein SoxY; Region: SoxY;
                     pfam13501"
                     /db_xref="CDD:222179"
     gene            complement(772425..772772)
                     /gene="soxX"
                     /locus_tag="COSY_0733"
                     /db_xref="GeneID:5171986"
     CDS             complement(772425..772772)
                     /gene="soxX"
                     /locus_tag="COSY_0733"
                     /note="cytochrome c"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur oxidation protein SoxX"
                     /protein_id="YP_001219569.1"
                     /db_xref="GI:148244875"
                     /db_xref="GeneID:5171986"
                     /translation="MKEAISSIPTVVILIVLFMISAQTGAKEMTGEEVTFGRKLGNCL
                     ACHMIPGGSLPGTIGPPLFAMKERFPNKADLRKQIWDATIKNPYSIMPPFGKHQILTE
                     NQIDQITDFIYSK"
     misc_feature    complement(772437..772649)
                     /gene="soxX"
                     /locus_tag="COSY_0733"
                     /note="Cytochrome C oxidase, cbb3-type, subunit III;
                     Region: Cytochrome_CBB3; pfam13442"
                     /db_xref="CDD:205620"
     gene            complement(772996..774450)
                     /locus_tag="COSY_0734"
                     /db_xref="GeneID:5171945"
     CDS             complement(772996..774450)
                     /locus_tag="COSY_0734"
                     /EC_number="2.6.1.85"
                     /note="Similar to anthranilate synthase component I
                     (EC:4.1.3.27) TrpE."
                     /codon_start=1
                     /transl_table=11
                     /product="para-aminobenzoate synthetase component I"
                     /protein_id="YP_001219570.1"
                     /db_xref="GI:148244876"
                     /db_xref="GeneID:5171945"
                     /translation="MNQSSFNQFVKQGYNHIPVFKEVILDTDTALGLYLKLADTPYSY
                     LFESVQGGEKWGRYSIIGLSAQTVIKVFGNEVRIEQDTQLLESLIVADPLLWIEKYQQ
                     KYSVPKINNLPEFNGGLVGYFGYEIIHYIEPKLKFSKQKDEFNIADIMLMVSNDLVVF
                     DNLANKAFLITHINPVKQDFEDAQLRLSKIKRQINQPLIKKDYQSHHFSDINFTSSFG
                     EQNYKIAVDTIQQYIKSGDVMQVVPSQRLSATFKASPIELYRQLRRLNPSPYMYYLNL
                     DDIMIIGSSPEILTRVDNNRRATIRPMAGTRSRGKDHAQDLELEQDLLNDEKEIAEHL
                     MLIDLGRNDLGRIAKTGTVKLTDRMFVERYSHVMHIVSNVECELKDDVSVIDVLKATF
                     PAGTLSGAPKVRAMEIINEVEPLKRNIYSGAIGYLSWHGCMDMAIAIRTAVIKEQILY
                     VQAGAGIVYDSTAQSEWDETMHKAQALIKAAQQV"
     misc_feature    complement(772999..774450)
                     /locus_tag="COSY_0734"
                     /note="anthranilate synthase component I; Provisional;
                     Region: PRK13565"
                     /db_xref="CDD:184146"
     misc_feature    complement(773944..774375)
                     /locus_tag="COSY_0734"
                     /note="Anthranilate synthase component I, N terminal
                     region; Region: Anth_synt_I_N; pfam04715"
                     /db_xref="CDD:218224"
     misc_feature    complement(773032..773799)
                     /locus_tag="COSY_0734"
                     /note="chorismate binding enzyme; Region: Chorismate_bind;
                     pfam00425"
                     /db_xref="CDD:215913"
     gene            complement(774538..778719)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /db_xref="GeneID:5172352"
     CDS             complement(774538..778719)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /EC_number="2.7.7.6"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase beta' subunit"
                     /protein_id="YP_001219571.1"
                     /db_xref="GI:148244877"
                     /db_xref="GeneID:5172352"
                     /translation="MRDLLKIHKLEQKEQDFDAIRVGLASPEKIRSWSYGEVKKPETI
                     NYRTFKPEREGLFCAKVFGPMKDFECLCGKYKRMKFRNVVCEKCGVEVTYSKVRRERM
                     GHIELAAPVAHIWYLKSLPSRLGLLMDMTLKDIERVLYFEAFLVTDPGSTPLVHKQLL
                     TEEMYFDALDEYGDDEFEAKMGAEAIQDVLSDMKLEVEAANLREDSLNTKSQTKLKKY
                     NKRLKLVNSLIQSGNKPEWMVLKVLPILPSDLRPLVPLDGGRFATSDLNDLYRRVINR
                     NNRLARLLELDAPEIIVRNEKRMLQEAVDSLIDNGRRGRAVMGNNRRPLKSISDMIKG
                     KQGRFRQNLLGKRVDYSGRSVIVCGPYLKLHQCGLPKKMALELFKPFIYNRLQTKGLA
                     STIKAAKKMVESESPEVWDILERVVHQHPVLLNRAPTLHRLGIQAFEPLLIEGKAIQL
                     HPLVCGAFNADFDGDQMAVHVPLSEEAQLEARTLMLASNNVLHLASGEPIIVPSQDVI
                     LGLYYMTREMINQKGEGLIFVNATEALNAYESDSVTLHAKVKLRIQDYHKVNGKFEPS
                     AKRIVDTTVGRAIFSRILPNGLSFNLINEAISKKVVSNLIHVCYRTQELKQTVMFADQ
                     MMYMGFQYSTKSGISFCSNDMIIPDSKAKMIEQAEIQVKDIQEQFSKGVVTDGERYNK
                     VIDIWSRTSEKVAKAMMDEIGFENFTDVDGKIQKLASFNSVYMMADSGARGSPAQMRQ
                     LSGMRGLMAKPDGSIIETPITSNFREGLNNMQYFISTHGARKGLADTALKTANSGYLT
                     RRLVDVGQDLVITENDCGTDNGLIMKAVIDGGNIVQTLGTATLGRVTAEDVLMPDSIE
                     IFLEKGHLVSLDDSDKINELGIESIKVRSSITCDTRYGVCSSCYGNDMARGHKIGVGE
                     AIGVIAAQSIGEPGTQLTMRTFHIGGAASASTAVSSINVNTDGIAHFENLKSITNENN
                     DLVVISRSSEVTIRNNKGQEVERYKIPYGAIVHVQEGGAVTAKDKISDWDPHTHPIIS
                     EQAGRVIFVDFVEGMTVNKNTDPLTGLTFFEMIDEAERSTAAKGLKPLIKMVEENDSE
                     VVLSTHYLPSTVKINLDDNQVIAAGGVLAKIPKDLSKTSDITGGLPRVADLFEARKAK
                     DHSILAEATGVISFGNSTKSKDRLIITSSEGKATEMMIHKWSQINVFDGETIEKGDVI
                     SDGPSNPHDILRLLGVEALANYVVREVQNVYRLQGVNISDKHIEVIVKQMLRKVEILD
                     AGDSSFVNGETAEYGRVIEMNYQLEAQGKDLINYQRLLMGITKASLATESFISAASFQ
                     ETTRVLTEASTTGRVDTLQGLKENVIVGRLIPAGTGFKHHQVRRAQYVESITTQTVDA
                     QQALSDQLKEAEEQT"
     misc_feature    complement(777691..778680)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="RNA polymerase Rpb1, domain 1; Region:
                     RNA_pol_Rpb1_1; pfam04997"
                     /db_xref="CDD:218370"
     misc_feature    complement(776158..778662)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="DNA-directed RNA polymerase, beta&apos; subunit/160
                     kD subunit [Transcription]; Region: RpoC; COG0086"
                     /db_xref="CDD:223164"
     misc_feature    complement(777184..778014)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="RNA polymerase I subunit A N-terminus; Region:
                     RPOLA_N; smart00663"
                     /db_xref="CDD:214767"
     misc_feature    complement(776785..777252)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="RNA polymerase Rpb1, domain 3; Region:
                     RNA_pol_Rpb1_3; pfam04983"
                     /db_xref="CDD:218361"
     misc_feature    complement(776425..776700)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="RNA polymerase Rpb1, domain 4; Region:
                     RNA_pol_Rpb1_4; pfam05000"
                     /db_xref="CDD:218372"
     misc_feature    complement(<775399..776421)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="RNA polymerase Rpb1, domain 5; Region:
                     RNA_pol_Rpb1_5; pfam04998"
                     /db_xref="CDD:147266"
     misc_feature    complement(<775900..775998)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="Largest subunit of RNA polymerase (RNAP),
                     C-terminal domain; Region: RNAP_largest_subunit_C;
                     cl11429"
                     /db_xref="CDD:142634"
     misc_feature    complement(775978..775980)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="Rpb1 - Rpb6 interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:132719"
     misc_feature    complement(<775267..775341)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="Largest subunit of RNA polymerase (RNAP),
                     C-terminal domain; Region: RNAP_largest_subunit_C;
                     cl11429"
                     /db_xref="CDD:142634"
     misc_feature    complement(774649..>775098)
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="Largest subunit (beta&apos;) of Bacterial
                     DNA-dependent RNA polymerase (RNAP), C-terminal domain;
                     Region: RNAP_beta&apos;_C; cd02655"
                     /db_xref="CDD:132721"
     misc_feature    complement(order(774757..774762,774805..774807))
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:132721"
     misc_feature    complement(order(774655..774657,774667..774672,
                     774679..774681,774697..774699,774715..774717))
                     /gene="rpoC"
                     /locus_tag="COSY_0735"
                     /note="Rpb1 (beta') - Rpb2 (beta) interaction site
                     [polypeptide binding]; other site"
                     /db_xref="CDD:132721"
     gene            complement(778733..782815)
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /db_xref="GeneID:5172602"
     CDS             complement(778733..782815)
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /EC_number="2.7.7.6"
                     /note="DNA-dependent RNA polymerase catalyzes the
                     transcription of DNA into RNA using the four
                     ribonucleoside triphosphates as substrates; beta subunit
                     is part of the catalytic core which binds with a sigma
                     factor to produce the holoenzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="YP_001219572.1"
                     /db_xref="GI:148244878"
                     /db_xref="GeneID:5172602"
                     /translation="MAYSFTEKKRIRNNFGSRESILTEPDLLAIQIDSFNSFIQADNK
                     IKQDIGLHNVLQSVFPITAVNGYAQIEYVDYQLKEPKFNVEECKLRGVTFASTLRVKL
                     NLVLFDKNGSTLKKKRKVKQIIEEDVYLGQLPLMTETGTFVINGTERVVVSQLHRSPG
                     VIFEHDKGKTHSSGKILFSSRIIPYRGSWLDFEYDHHEHLYVRIDRRRKLPVTTLLRA
                     MGLSSEDILETFFEKTPVKLKAKSCDLSMLPIHLQRTIAEFDIVVNQHVVVEKGRRIT
                     AKHVKLLGKAGIKSINAPLEYLLDKVICADIINKDTGEILISANTITSEEVLELLNTN
                     KVKKIEILYINSSETGAYISDTLRLDETQTEIEARMSIYHVMRPGEPATEDAVNLLFN
                     NLFFKNDRYDLSKVGRMKLNRRLGISRETGEHVLTNDDIIRVIKLLINIKDGNDSVDD
                     IDTLANRRVRAIGEMIENQFRIGLVRVEKAVREGLNLAETDELTPQDLINSKPVSAAV
                     REFFGSSQLSQFMDQVNPLSGVTHKRRISALGPGGLTRERAGFEVRDVHPSHYGRLCP
                     IETPEGPNIGLINTLAVYAKTNSYGFLETPYQIVKNGKVTKEVIYVSAIDEITHTIAQ
                     ANALVDDRGKLMDDLISCRHKNEFVLVDSSEVTLIDIDSKQISSVAASLIPFLEHDDA
                     NRALMGSNMQRQAVPVLKAEKPLVGTGIERVVAKDSRVCVTAKHGGVVEAVDASRIVI
                     RVDSKKTKANELGVDIYNLTKYSRSNQNTCINQKPLVRTGDKITFGDVLADGPSTDMG
                     ELALGQNMKIAFMPWNGYNFEDSILISEKVVQEDRYTTIHIEELTAYSRDTKLGPEEI
                     TSDIPNVSESALSKLDEVGVVYVGARVKGGDILVGKVTPKSETVLSPEEKLLRAIFGE
                     KANNVKDSSLRIGASKSGVVIDVQVFTRDRVEKDIRALSIDAERLERIKKDIDDEFSI
                     IDGDIFRRIRLKLLGNVLSKAIGDIRIGERLSIKLMKKFDNKDIAKFKVENATVNKEV
                     AVLVKQAKAKKVEFEKFFKKEKAKINEGAELPPGVMKMVKVYVATRKTLQVGDKMAGR
                     HGNKGVISRVSPVEDMPYLADGSTIDIVLNPLGVPSRMNVGQVLEVHLGYAAKGLGYK
                     IAAILDERRPDMVKQIRVFLDKVYNLHGKKEDLTLFSNEEIIELANNLREGVPMATPV
                     FDGIREQDIKSLLRLADLPESGQEQLYDGRTGEPFDRHVTVGYMHMLKLNHLVDDKMH
                     ARSTGPYSLVTQQPLSGKAQFGGQRFGEMEVWALEAYGAAHTLREMLTVKSDDVAGRA
                     KMYKSIVDGKNLTESVMPESFNVLVKEIRSLGIDVELEQH"
     misc_feature    complement(<779987..782815)
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="DNA-directed RNA polymerase subunit beta; Reviewed;
                     Region: rpoB; PRK00405"
                     /db_xref="CDD:234749"
     misc_feature    complement(<782189..782737)
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="RNA polymerase beta subunit. RNA polymerases
                     catalyse the DNA dependent polymerization of RNA.
                     Prokaryotes contain a single RNA polymerase compared to
                     three in eukaryotes (not including mitochondrial. and
                     chloroplast polymerases). Each RNA polymerase...; Region:
                     RNA_pol_B_RPB2; cl17585"
                     /db_xref="CDD:248139"
     misc_feature    complement(<781985..782347)
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="RNA polymerase Rpb2, domain 2; Region:
                     RNA_pol_Rpb2_2; pfam04561"
                     /db_xref="CDD:218151"
     misc_feature    complement(<779966..>781531)
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="RNA polymerase beta subunit. RNA polymerases
                     catalyse the DNA dependent polymerization of RNA.
                     Prokaryotes contain a single RNA polymerase compared to
                     three in eukaryotes (not including mitochondrial. and
                     chloroplast polymerases). Each RNA polymerase...; Region:
                     RNA_pol_B_RPB2; cd00653"
                     /db_xref="CDD:238353"
     misc_feature    complement(order(780326..780328,780368..780370))
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="RPB11 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238353"
     misc_feature    complement(order(780170..780172,780176..780184,
                     780194..780196,780200..780202,780311..780313))
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="RPB12 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238353"
     misc_feature    complement(778742..>779638)
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="RNA polymerase beta subunit. RNA polymerases
                     catalyse the DNA dependent polymerization of RNA.
                     Prokaryotes contain a single RNA polymerase compared to
                     three in eukaryotes (not including mitochondrial. and
                     chloroplast polymerases). Each RNA polymerase...; Region:
                     RNA_pol_B_RPB2; cd00653"
                     /db_xref="CDD:238353"
     misc_feature    complement(order(779090..779092,779096..779119,
                     779489..779494,779498..779500,779507..779515,
                     779588..779590,779594..779596))
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="RPB3 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238353"
     misc_feature    complement(order(778742..778744,778748..778750,
                     778754..778765,778769..778771,778775..778780,
                     778784..778786,778790..778792,778802..778804,
                     778871..778873,778883..778900,778904..778921,
                     778925..778927,778931..778936,778940..778942,
                     778952..778960,779021..779026,779030..779038,
                     779045..779047,779084..779086,779090..779098,
                     779120..779122,779201..779203,779411..779413,
                     779423..779425,779438..779440,779447..779449,
                     779456..779458,779462..779464,779528..779530,
                     779534..779536,779540..779542))
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="RPB1 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238353"
     misc_feature    complement(order(779114..779116,779516..779518))
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="RPB11 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238353"
     misc_feature    complement(order(779081..779083,779132..779134,
                     779294..779296,779300..779302,779393..779395,
                     779474..779476,779513..779515))
                     /gene="rpoB"
                     /locus_tag="COSY_0736"
                     /note="RPB10 interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238353"
     gene            complement(782985..783359)
                     /gene="rplL"
                     /locus_tag="COSY_0737"
                     /db_xref="GeneID:5172590"
     CDS             complement(782985..783359)
                     /gene="rplL"
                     /locus_tag="COSY_0737"
                     /note="present in two forms; L12 is normal, while L7 is
                     aminoacylated at the N-terminal serine; the only multicopy
                     ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two
                     L12 dimers bind L10; critically important for translation
                     efficiency and fidelity; stimulates GTPase activity of
                     translation factors"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="YP_001219573.1"
                     /db_xref="GI:148244879"
                     /db_xref="GeneID:5172590"
                     /translation="MAKLTNEDILNAIADMSVIDVVELVSAMEEKFGVSATAVTPVAV
                     VADVDNTVVEKDEFDIMLTSFGEKKVAVIKAVRSITGLGLKESKDMVESAPVVIKESA
                     SKIEAEDIERQLKEVGASVELK"
     misc_feature    complement(782991..783350)
                     /gene="rplL"
                     /locus_tag="COSY_0737"
                     /note="Ribosomal protein L7/L12. Ribosomal protein L7/L12
                     refers to the large ribosomal subunit proteins L7 and L12,
                     which are identical except that L7 is acetylated at the N
                     terminus. It is a component of the L7/L12 stalk, which is
                     located at the surface of...; Region: Ribosomal_L7_L12;
                     cd00387"
                     /db_xref="CDD:100102"
     misc_feature    complement(order(783042..783044,783051..783053,
                     783057..783062,783102..783107,783111..783113,
                     783117..783122,783126..783128,783189..783194,
                     783204..783212,783216..783221,783228..783230,
                     783273..783275,783282..783284,783291..783296,
                     783303..783311,783348..783350))
                     /gene="rplL"
                     /locus_tag="COSY_0737"
                     /note="core dimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100102"
     misc_feature    complement(order(783264..783266,783279..783281,
                     783318..783320,783330..783332,783339..783341))
                     /gene="rplL"
                     /locus_tag="COSY_0737"
                     /note="peripheral dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:100102"
     misc_feature    complement(order(783264..783266,783273..783275,
                     783285..783290,783297..783299))
                     /gene="rplL"
                     /locus_tag="COSY_0737"
                     /note="L10 interface [polypeptide binding]; other site"
                     /db_xref="CDD:100102"
     misc_feature    complement(order(783096..783098,783105..783110,
                     783129..783131,783138..783143,783150..783155))
                     /gene="rplL"
                     /locus_tag="COSY_0737"
                     /note="L11 interface [polypeptide binding]; other site"
                     /db_xref="CDD:100102"
     misc_feature    complement(order(783096..783098,783105..783110,
                     783129..783131,783138..783140,783150..783152))
                     /gene="rplL"
                     /locus_tag="COSY_0737"
                     /note="putative EF-Tu interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:100102"
     misc_feature    complement(order(783129..783131,783138..783143,
                     783150..783152))
                     /gene="rplL"
                     /locus_tag="COSY_0737"
                     /note="putative EF-G interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:100102"
     gene            complement(783382..783906)
                     /gene="rplJ"
                     /locus_tag="COSY_0738"
                     /db_xref="GeneID:5172726"
     CDS             complement(783382..783906)
                     /gene="rplJ"
                     /locus_tag="COSY_0738"
                     /note="binds the two ribosomal protein L7/L12 dimers and
                     anchors them to the large ribosomal subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="YP_001219574.1"
                     /db_xref="GI:148244880"
                     /db_xref="GeneID:5172726"
                     /translation="MALNLMAKKAVVAQVNLLARVSVSIGVAEYCGLTVEQMTNLRSS
                     AIDADVVLRVVKNSLAKRALVSTKCECVLPVLSGPVILGFSQQDLGAVARVFKNFIKE
                     NKDLVVKGLGVSGEFVESNQLKRIADLPTRDQAISIIMALMLAPVEKLARTLIEVPMK
                     VTRVVEAVCDQKKS"
     misc_feature    complement(783433..783897)
                     /gene="rplJ"
                     /locus_tag="COSY_0738"
                     /note="Ribosomal protein L10 family, L10 subfamily;
                     composed of bacterial 50S ribosomal protein and eukaryotic
                     mitochondrial 39S ribosomal protein, L10. L10 occupies the
                     L7/L12 stalk of the ribosome. The N-terminal domain (NTD)
                     of L10 interacts with L11 protein...; Region:
                     Ribosomal_L10; cd05797"
                     /db_xref="CDD:240223"
     misc_feature    complement(order(783721..783723,783730..783741,
                     783871..783873,783880..783885))
                     /gene="rplJ"
                     /locus_tag="COSY_0738"
                     /note="23S rRNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:240223"
     misc_feature    complement(order(783433..783438,783442..783447,
                     783454..783462,783466..783483,783487..783492,
                     783499..783504,783511..783513,783559..783561,
                     783568..783570,783637..783639))
                     /gene="rplJ"
                     /locus_tag="COSY_0738"
                     /note="Interface with L7/L12 ribosomal proteins
                     [polypeptide binding]; other site"
                     /db_xref="CDD:240223"
     gene            complement(784107..784802)
                     /gene="rplA"
                     /locus_tag="COSY_0739"
                     /db_xref="GeneID:5172710"
     CDS             complement(784107..784802)
                     /gene="rplA"
                     /locus_tag="COSY_0739"
                     /note="in Escherichia coli and Methanococcus, this protein
                     autoregulates expression; the binding site in the mRNA
                     mimics the binding site in the 23S rRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="YP_001219575.1"
                     /db_xref="GI:148244881"
                     /db_xref="GeneID:5172710"
                     /translation="MAKLTKNQKYISTKVEHNKYYSINDALNLLKICAIAKFDESIDV
                     SINLGIDVKKYDQNIRGSVILPNGTGKVVRVAVFTQGDNVIKAQDAGADVVGMEDLMK
                     SMQGGDLSYDVVIASPDAMGVVGRLGQLLGPRGLMPNPKVGTVTSDVSLAVSNAKSGQ
                     LRYRADKAGIIHGCVGKVSFNISALAQNINVLIGELKKVKPSSAKGVYFKKLSISSTM
                     GPGFSVDLASVDI"
     misc_feature    complement(784131..784736)
                     /gene="rplA"
                     /locus_tag="COSY_0739"
                     /note="Ribosomal protein L1.  The L1 protein, located near
                     the E-site of the ribosome, forms part of the L1 stalk
                     along with 23S rRNA.  In bacteria and archaea, L1
                     functions both as a ribosomal protein that binds rRNA, and
                     as a translation repressor that binds...; Region:
                     Ribosomal_L1; cd00403"
                     /db_xref="CDD:238235"
     misc_feature    complement(order(784140..784142,784146..784151,
                     784287..784289,784293..784295,784299..784301,
                     784662..784664,784668..784670,784674..784676,
                     784680..784682,784689..784697))
                     /gene="rplA"
                     /locus_tag="COSY_0739"
                     /note="mRNA/rRNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238235"
     gene            complement(784807..785235)
                     /gene="rplK"
                     /locus_tag="COSY_0740"
                     /db_xref="GeneID:5172643"
     CDS             complement(784807..785235)
                     /gene="rplK"
                     /locus_tag="COSY_0740"
                     /note="binds directly to 23S ribosomal RNA"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="YP_001219576.1"
                     /db_xref="GI:148244882"
                     /db_xref="GeneID:5172643"
                     /translation="MAKKIESYIKLQVAAQEANPSPPVGPALGQHGVNIMEFCKAFNS
                     KTQEINKGMKVPVVITVYSDRSFSFVTKTPPAALLILKIIDIKKGSGSPHLDKVGSIT
                     RAQLEEVASMKMKDLNANNMDSAVNIIAGTARSMGIMVEG"
     misc_feature    complement(784810..785235)
                     /gene="rplK"
                     /locus_tag="COSY_0740"
                     /note="50S ribosomal protein L11; Validated; Region: rplK;
                     PRK00140"
                     /db_xref="CDD:234661"
     misc_feature    complement(784816..785211)
                     /gene="rplK"
                     /locus_tag="COSY_0740"
                     /note="Ribosomal protein L11. Ribosomal protein L11,
                     together with proteins L10 and L7/L12, and 23S rRNA, form
                     the L7/L12 stalk on the surface of the large subunit of
                     the ribosome. The homologous eukaryotic cytoplasmic
                     protein is also called 60S ribosomal...; Region:
                     Ribosomal_L11; cd00349"
                     /db_xref="CDD:100101"
     misc_feature    complement(order(784828..784836,784840..784845,
                     784852..784857,784864..784866,784876..784884,
                     784897..784899,784972..784974,784993..784995,
                     785005..785013,785146..785148,785206..785208))
                     /gene="rplK"
                     /locus_tag="COSY_0740"
                     /note="23S rRNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:100101"
     misc_feature    complement(order(784879..784884,784891..784896,
                     785026..785031,785035..785037,785047..785058,
                     785062..785064,785206..785208))
                     /gene="rplK"
                     /locus_tag="COSY_0740"
                     /note="L7/L12 interface [polypeptide binding]; other site"
                     /db_xref="CDD:100101"
     misc_feature    complement(order(785146..785148,785158..785160))
                     /gene="rplK"
                     /locus_tag="COSY_0740"
                     /note="putative thiostrepton binding site; other site"
                     /db_xref="CDD:100101"
     misc_feature    complement(order(784945..784947,784954..784956))
                     /gene="rplK"
                     /locus_tag="COSY_0740"
                     /note="L25 interface [polypeptide binding]; other site"
                     /db_xref="CDD:100101"
     gene            complement(785326..785859)
                     /gene="nusG"
                     /locus_tag="COSY_0741"
                     /db_xref="GeneID:5172713"
     CDS             complement(785326..785859)
                     /gene="nusG"
                     /locus_tag="COSY_0741"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination protein NusG"
                     /protein_id="YP_001219577.1"
                     /db_xref="GI:148244883"
                     /db_xref="GeneID:5172713"
                     /translation="MSKRWYVFHARSGFESKVKIAIEESTIREGLEDLVGEVLVPTEQ
                     VVELKDGQKKMAERKFFPGYMLVNMELTEPSWLLVKNTNNVIGFIGGSSGKPSPITQR
                     EVDKILMRVQEGADKPKPKVAYQPGEEILVIDGPFNEFNGLVEAVDYEKNLLKVEVLI
                     FGRSTSVELEFSQVEKT"
     misc_feature    complement(785332..785859)
                     /gene="nusG"
                     /locus_tag="COSY_0741"
                     /note="transcription antitermination protein NusG;
                     Validated; Region: nusG; PRK05609"
                     /db_xref="CDD:180161"
     misc_feature    complement(785527..785850)
                     /gene="nusG"
                     /locus_tag="COSY_0741"
                     /note="Bacterial N-Utilization Substance G (NusG)
                     N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1;
                     cd09891"
                     /db_xref="CDD:193580"
     misc_feature    complement(order(785539..785541,785563..785565,
                     785662..785664,785668..785670,785677..785679,
                     785737..785739,785839..785841))
                     /gene="nusG"
                     /locus_tag="COSY_0741"
                     /note="putative homodimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:193580"
     misc_feature    complement(785332..785499)
                     /gene="nusG"
                     /locus_tag="COSY_0741"
                     /note="NusG contains an NGN domain at its N-terminus and
                     KOW motif at its C-terminus; Region: KOW_NusG; cd06091"
                     /db_xref="CDD:240515"
     misc_feature    complement(order(785341..785346,785356..785367,
                     785371..785379,785404..785406,785440..785442,
                     785449..785463))
                     /gene="nusG"
                     /locus_tag="COSY_0741"
                     /note="heterodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240515"
     misc_feature    complement(785452..785463)
                     /gene="nusG"
                     /locus_tag="COSY_0741"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240515"
     gene            complement(785870..786241)
                     /gene="secE"
                     /locus_tag="COSY_0742"
                     /db_xref="GeneID:5171902"
     CDS             complement(785870..786241)
                     /gene="secE"
                     /locus_tag="COSY_0742"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase SecE subunit"
                     /protein_id="YP_001219578.1"
                     /db_xref="GI:148244884"
                     /db_xref="GeneID:5171902"
                     /translation="MTKVTEPKAKQSLLGMIVSILIVVVSFVFFYLNPLGLSTTLYKV
                     LFLLTGFLLSGFVFFKSPQGVRFSSFLIETKIELRKVVWPTRDETIKTTGMIMVAVVI
                     VAIFLWIIDALFSWMVHLLTN"
     misc_feature    complement(785876..>786055)
                     /gene="secE"
                     /locus_tag="COSY_0742"
                     /note="preprotein translocase subunit SecE; Reviewed;
                     Region: secE; PRK05740"
                     /db_xref="CDD:235587"
     gene            complement(786258..786333)
                     /locus_tag="COSY_t25"
                     /db_xref="GeneID:5329753"
     tRNA            complement(786258..786333)
                     /locus_tag="COSY_t25"
                     /product="tRNA-Trp"
                     /db_xref="GeneID:5329753"
     gene            complement(786412..787602)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /db_xref="GeneID:5171820"
     CDS             complement(786412..787602)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /EC_number="3.6.5.3"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="YP_001219579.1"
                     /db_xref="GI:148244885"
                     /db_xref="GeneID:5171820"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITKVMAEVRGGEF
                     KDYADIDNAPEERERGITISTAHVEYESEIRHYAHVDCPGHADYIKNMITGAAQMDGA
                     IIVIAATDGPMAQTREHILLSKQVGVPYIVVYMNKADMVDDEELVELVEMEIRELLDE
                     YDFPGDDTPVIFGSALKALEGDISDIGVPSILKLVDALDSYIPTPKRDTDKSFIMPIE
                     DVFSISGRGTVVTGRIEAGVVNIGDELEIVGIKDTKTTTCTGVEMFRKLLSSGEAGDN
                     VGVLLRGTKREEVERGQVLSKPGSIKPHAKFEAEIYILSKDEGGRHTPFFNNYRPQFY
                     FRTTDVTGACQLPDGIEMVMPGDNVKMRVELLSPIAMEDGLRFAIREGGRTVGAGVVS
                     KVTD"
     misc_feature    complement(786415..787602)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="elongation factor Tu; Reviewed; Region: PRK00049"
                     /db_xref="CDD:234596"
     misc_feature    complement(786988..787572)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="Elongation Factor Tu (EF-Tu) GTP-binding proteins;
                     Region: EF_Tu; cd01884"
                     /db_xref="CDD:206671"
     misc_feature    complement(787525..787548)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="G1 box; other site"
                     /db_xref="CDD:206671"
     misc_feature    complement(order(787063..787068,787144..787146,
                     787156..787158,787249..787251,787258..787269,
                     787273..787278,787345..787350,787402..787407,
                     787489..787491,787501..787506,787513..787515,
                     787522..787527,787537..787539,787543..787545))
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="GEF interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:206671"
     misc_feature    complement(order(787075..787083,787186..787188,
                     787192..787197,787462..787464,787522..787539))
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206671"
     misc_feature    complement(787405..787437)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206671"
     misc_feature    complement(787417..787419)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="G2 box; other site"
                     /db_xref="CDD:206671"
     misc_feature    complement(787351..787362)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="G3 box; other site"
                     /db_xref="CDD:206671"
     misc_feature    complement(787300..787356)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206671"
     misc_feature    complement(787186..787197)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="G4 box; other site"
                     /db_xref="CDD:206671"
     misc_feature    complement(787075..787083)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="G5 box; other site"
                     /db_xref="CDD:206671"
     misc_feature    complement(786706..786966)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="EFTU_II: Elongation factor Tu domain II. Elongation
                     factors Tu (EF-Tu) are three-domain GTPases with an
                     essential function in the elongation phase of mRNA
                     translation. The GTPase center of EF-Tu is in the
                     N-terminal domain (domain I), also known as the...;
                     Region: EFTU_II; cd03697"
                     /db_xref="CDD:239668"
     misc_feature    complement(786430..786699)
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="Domain III of elongation factor (EF) Tu. Ef-Tu
                     consists of three structural domains, designated I, II and
                     III. Domain III adopts a beta barrel structure. Domain III
                     is involved in binding to both charged tRNA and binding to
                     elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707"
                     /db_xref="CDD:239678"
     misc_feature    complement(order(786439..786441,786469..786477,
                     786595..786597,786649..786657,786661..786663))
                     /gene="tufB"
                     /locus_tag="COSY_0744"
                     /gene_synonym="tuf"
                     /note="Antibiotic Binding Site [chemical binding]; other
                     site"
                     /db_xref="CDD:239678"
     gene            complement(787637..787712)
                     /locus_tag="COSY_t26"
                     /db_xref="GeneID:5329755"
     tRNA            complement(787637..787712)
                     /locus_tag="COSY_t26"
                     /product="tRNA-Thr"
                     /db_xref="GeneID:5329755"
     gene            complement(787728..787801)
                     /locus_tag="COSY_t27"
                     /db_xref="GeneID:5329736"
     tRNA            complement(787728..787801)
                     /locus_tag="COSY_t27"
                     /product="tRNA-Gly"
                     /db_xref="GeneID:5329736"
     gene            complement(787821..787905)
                     /locus_tag="COSY_t28"
                     /db_xref="GeneID:5329737"
     tRNA            complement(787821..787905)
                     /locus_tag="COSY_t28"
                     /product="tRNA-Tyr"
                     /db_xref="GeneID:5329737"
     gene            complement(788001..789221)
                     /gene="maeB"
                     /locus_tag="COSY_0748"
                     /db_xref="GeneID:5171849"
     CDS             complement(788001..789221)
                     /gene="maeB"
                     /locus_tag="COSY_0748"
                     /EC_number="1.1.1.40"
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase
                     (oxaloacetate-decarboxylating)(NADP+)"
                     /protein_id="YP_001219580.1"
                     /db_xref="GI:148244886"
                     /db_xref="GeneID:5171849"
                     /translation="MSSKFHKLALEYHKGNRPGKIIVSSHKSLTTCEDLSLAYTPGVA
                     IPVREIAQDANKVYDFTIKRNLVAVISDGSAVLGLGNVGPLASKPVMEGKAVLFKHFA
                     DIDVFDIEIDTQDVDDFVQTVKNIAPTFGGINLEDISAPRCFEIEKRLIEMLDIPVFH
                     DDQHGTAIIIAAGLLNSLEIQNKDIETIQLVCLGAGSAGIATLDLLCELGLSKDNILL
                     VDSGGVISKDMENVSQVKAQYGTKTDKKTLTDVMQGADVFIGVAVANLVSKQMIKSMA
                     DRPIVFALSNPDPEISPKDANSVRDDLIMATGRSDYPNQVNNVLGFPFIFRGALDAKA
                     SEINLKMKIAAVYALKDLAKLEVPNSVLKAYSTKYMTFGKDYIIPKPFDPRLIEVVPK
                     AVFDVAVSSGVSRL"
     misc_feature    complement(788007..789221)
                     /gene="maeB"
                     /locus_tag="COSY_0748"
                     /note="Malic enzyme [Energy production and conversion];
                     Region: SfcA; COG0281"
                     /db_xref="CDD:223358"
     misc_feature    complement(788769..789170)
                     /gene="maeB"
                     /locus_tag="COSY_0748"
                     /note="Malic enzyme, N-terminal domain; Region: malic;
                     pfam00390"
                     /db_xref="CDD:215894"
     misc_feature    complement(788028..788735)
                     /gene="maeB"
                     /locus_tag="COSY_0748"
                     /note="NAD(P) binding domain of malic enzyme (ME),
                     subgroup 2; Region: NAD_bind_2_malic_enz; cd05311"
                     /db_xref="CDD:133453"
     misc_feature    complement(order(788268..788270,788274..788276,
                     788298..788300,788364..788372,788424..788426,
                     788436..788441,788559..788564,788628..788639))
                     /gene="maeB"
                     /locus_tag="COSY_0748"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:133453"
     gene            complement(789721..790059)
                     /locus_tag="COSY_0749"
                     /db_xref="GeneID:5172229"
     CDS             complement(789721..790059)
                     /locus_tag="COSY_0749"
                     /note="histidine triad nucleotide-binding protein (HIT)
                     family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
                     /protein_id="YP_001219581.1"
                     /db_xref="GI:148244887"
                     /db_xref="GeneID:5172229"
                     /translation="MTDCLFCTIINGDISVNKIYEDEDVLAFYDIKPRAPYHFLVIPK
                     THIKTLNNTNDEKLLGKLILIASDITQDLGFADKGYRVVMNCNKQGGQTVYHIHLHCL
                     GGRVLTWPPG"
     misc_feature    complement(789748..790053)
                     /locus_tag="COSY_0749"
                     /note="Protein Kinase C Interacting protein related
                     (PKCI): PKCI and related proteins belong to the ubiquitous
                     HIT family of hydrolases that act on alpha-phosphates of
                     ribonucleotides. The members of this subgroup have a
                     conserved HxHxHxx motif (x is a...; Region: PKCI_related;
                     cd01276"
                     /db_xref="CDD:238607"
     misc_feature    complement(order(789760..789762,789766..789768,
                     789778..789780,789784..789786,789805..789807,
                     789940..789942,789946..789948,789967..789972,
                     789976..789978))
                     /locus_tag="COSY_0749"
                     /note="nucleotide binding site/active site [active]"
                     /db_xref="CDD:238607"
     misc_feature    complement(order(789754..789762,789766..789768,
                     789772..789774))
                     /locus_tag="COSY_0749"
                     /note="HIT family signature motif; other site"
                     /db_xref="CDD:238607"
     misc_feature    complement(789766..789768)
                     /locus_tag="COSY_0749"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238607"
     gene            complement(790563..791690)
                     /locus_tag="COSY_0750"
                     /db_xref="GeneID:5172321"
     CDS             complement(790563..791690)
                     /locus_tag="COSY_0750"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide-quinone reductase"
                     /protein_id="YP_001219582.1"
                     /db_xref="GI:148244888"
                     /db_xref="GeneID:5172321"
                     /translation="MNKITIIGSGFAGLTAVRTLRKNDKHTQITLISPKAEFVYMPSL
                     IWIPSGIANKKDIVIPLNSFFKRMNIRHISGKVIGLENRARTVITSVGEYENDALIIA
                     SGGRFIKKLSGIEHAITPCDGVSAVEQIRDRIQVMDSGNIAIGFAANPNELSAIRGGP
                     MFEFLFGLDTQLRREGRRDKFNLTFFTPTEKPGARLGEKAVISLLSEMKKRNIKTHLG
                     HKIKSFEINKVITEGGEFIADLILFMPGMTGNHWFDSTELERSKGGLLKADKFCQVKG
                     AENIFVVGDSGSFPGPDWMPKQAHMADLQAVAAAKNVLAVLDDKPTSHTFKIELMCIV
                     DSNNKGMYISRTLKGGLMLPSCRLMHYAKQIFGWRYLRQYR"
     misc_feature    complement(790836..791684)
                     /locus_tag="COSY_0750"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox_2; pfam07992"
                     /db_xref="CDD:219686"
     gene            791950..792531
                     /locus_tag="COSY_0751"
                     /db_xref="GeneID:5172715"
     CDS             791950..792531
                     /locus_tag="COSY_0751"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219583.1"
                     /db_xref="GI:148244889"
                     /db_xref="GeneID:5172715"
                     /translation="MLNKDTLDTLFRHARSHNGWLKQDVSKTQFHQIYELMKFAPTAT
                     NNCPVRITFIKSHTAKQRLKPHLNEGNIDKSMNAPAIAIISYDTEFYKKLSFLFPHTN
                     AKSWYEGKPEKIKLAGSINATLQGAYFIMATRAIGLDCGPIGGFNKETLDDDFFTDGK
                     TKSIFLCGIGHGDHNKIFPRLPRLSFDEACKII"
     misc_feature    791965..792519
                     /locus_tag="COSY_0751"
                     /note="Nitroreductase-like family 5.  A subfamily of the
                     nitroreductase family containing uncharacterized proteins
                     that are similar to nitroreductase. Nitroreductase
                     catalyzes the reduction of nitroaromatic compounds such as
                     nitrotoluenes, nitrofurans and...; Region:
                     Nitroreductase_5; cd02148"
                     /db_xref="CDD:239061"
     misc_feature    order(791989..791991,791995..791997,792001..792003,
                     792079..792081,792379..792384)
                     /locus_tag="COSY_0751"
                     /note="putative FMN binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239061"
     gene            complement(792701..792949)
                     /locus_tag="COSY_0752"
                     /db_xref="GeneID:5172507"
     CDS             complement(792701..792949)
                     /locus_tag="COSY_0752"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219584.1"
                     /db_xref="GI:148244890"
                     /db_xref="GeneID:5172507"
                     /translation="MKGYSIDPHPSINIVKEVFAVIRIPRIKRERVPANNVEVVKDLD
                     VAIEKSDSSKNLYAAKVLGPSRSSEGIILYYILEMYNI"
     gene            complement(792965..793663)
                     /locus_tag="COSY_0753"
                     /db_xref="GeneID:5172498"
     CDS             complement(792965..793663)
                     /locus_tag="COSY_0753"
                     /EC_number="3.1.2.6"
                     /note="hydroxyacylglutathione hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase II"
                     /protein_id="YP_001219585.1"
                     /db_xref="GI:148244891"
                     /db_xref="GeneID:5172498"
                     /translation="MSLLLRPLFEKTSSTYTYLLADMKTLDAIIIDAVDETMQRDIAF
                     IRELGLNLKYIIETHVHADHITSSYLLKRYFTQAKIVLGSVNEIMCADILLNDGDILS
                     FGVYTLSAMTTPGHTNGCMSYVVGNQVFTGDTLLIRSCGRCDFQGGSAEKLYDSIQKI
                     FTLPDETLVYPAHDYEGRTMSSIWEEKQFNEMIGLNVDKQIFVSRVNKIKLDLPKKIH
                     VAVPANQDCGAKKL"
     misc_feature    complement(792980..793660)
                     /locus_tag="COSY_0753"
                     /note="Metallo-beta-lactamase superfamily; Region:
                     Lactamase_B; cl00446"
                     /db_xref="CDD:241867"
     gene            complement(793944..794687)
                     /gene="dapB"
                     /locus_tag="COSY_0754"
                     /db_xref="GeneID:5172492"
     CDS             complement(793944..794687)
                     /gene="dapB"
                     /locus_tag="COSY_0754"
                     /EC_number="1.3.1.26"
                     /note="catalyzes the reduction of 2,3-dihydrodipicolinate
                     to 2,3,4,5-tetrahydrodipicolinate in lysine and
                     diaminopimelate biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="YP_001219586.1"
                     /db_xref="GI:148244892"
                     /db_xref="GeneID:5172492"
                     /translation="MLKIAVSGSNGRMGQAIIEAIEQSNSIKLVIKIDQNNNLTNYLD
                     NFDVLIDFTYPAATLGYLSICAKAGKKMVIGTTGFNDDEFNQLTSLAKNIPIVFAPNM
                     SVGVNLSLKLLEIAAKVIGEDSDIEIVEMHHRFKADAPSGTALKMGEVIADTLGRDLK
                     TCAVYGRKGIKQIRDRNIIGFSTIRGGDVVGEHTVSFFMQGERVEITHKASSRMTFAL
                     GAIRAAEWLAKVPSNKGCIYSMKDVLEMS"
     misc_feature    complement(793950..794687)
                     /gene="dapB"
                     /locus_tag="COSY_0754"
                     /note="dihydrodipicolinate reductase; Provisional; Region:
                     PRK00048"
                     /db_xref="CDD:234595"
     misc_feature    complement(794382..794684)
                     /gene="dapB"
                     /locus_tag="COSY_0754"
                     /note="Dihydrodipicolinate reductase, N-terminus; Region:
                     DapB_N; pfam01113"
                     /db_xref="CDD:216304"
     misc_feature    complement(793956..794375)
                     /gene="dapB"
                     /locus_tag="COSY_0754"
                     /note="Dihydrodipicolinate reductase, C-terminus; Region:
                     DapB_C; pfam05173"
                     /db_xref="CDD:218479"
     gene            complement(794837..795670)
                     /gene="kdsA"
                     /locus_tag="COSY_0755"
                     /db_xref="GeneID:5172179"
     CDS             complement(794837..795670)
                     /gene="kdsA"
                     /locus_tag="COSY_0755"
                     /EC_number="2.5.1.55"
                     /note="catalyzes the formation of
                     2-dehydro-3-deoxy-D-octonate 8-phosphate from
                     phosphoenolpyruvate and D-arabinose 5-phosphate in LPS
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphooctonate aldolase"
                     /protein_id="YP_001219587.1"
                     /db_xref="GI:148244893"
                     /db_xref="GeneID:5172179"
                     /translation="MKLLDFEVGINHPFFLIAGPCVIESEALALETATYLKRVTEDLG
                     INFIYKSSYDKANRTSTNSFRGLGVKEGLRILQKVKDEVGVPVLTDVHEDTPLSEVAS
                     VVDMMQTPAFLVRQTNFIQNVCKQGIPVNIKKGQFQAPWDIGNVVNKAYETGNRLITI
                     CERGTSFGYNTLISDMRGLSTMRSTGCPIVFDATHSVQQPGGNGLTSGGQREMVPVVA
                     RAAIGVGVSGFFMETHPNPNEAFSDGPNMVPIDKIDELLKTLQELDAVTKKHGFLEDS
                     L"
     misc_feature    complement(794870..795658)
                     /gene="kdsA"
                     /locus_tag="COSY_0755"
                     /note="2-dehydro-3-deoxyphosphooctonate aldolase;
                     Provisional; Region: PRK05198"
                     /db_xref="CDD:235363"
     misc_feature    complement(794867..795646)
                     /gene="kdsA"
                     /locus_tag="COSY_0755"
                     /note="DAHP synthetase I family; Region: DAHP_synth_1;
                     pfam00793"
                     /db_xref="CDD:216123"
     gene            795875..796681
                     /gene="trpC"
                     /locus_tag="COSY_0756"
                     /db_xref="GeneID:5172728"
     CDS             795875..796681
                     /gene="trpC"
                     /locus_tag="COSY_0756"
                     /EC_number="4.1.1.48"
                     /note="involved in tryptophan biosynthesis; amino acid
                     biosynthesis; converts
                     1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to
                     C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide
                     and water"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol-phosphate synthase"
                     /protein_id="YP_001219588.1"
                     /db_xref="GI:148244894"
                     /db_xref="GeneID:5172728"
                     /translation="MMNTPDILKKIIARKKVEIAECKNNIPENQMLDVAYKNHNTNNF
                     YQALKDKVDTKQNAIIAEIKKASPSKGVLRENFNPVEIAESYEKSGATCLSVVTNKDF
                     FQGNNQHLIDVCEAISIPILHKEFIIDSYQIYESRTLGADCILLIAACLNDQQIEDFT
                     MQAININMDVLIEIHNIEELERTLQLRLPMIGVNNRNLHTFDVSLETTIELMKEIKED
                     TLIITESGILTSNDVAFMNKHNIYSFLVGEAFMRQDNPGKALQKIFGKNK"
     misc_feature    796004..796663
                     /gene="trpC"
                     /locus_tag="COSY_0756"
                     /note="Indole-3-glycerol phosphate synthase (IGPS); an
                     enzyme in the tryptophan biosynthetic pathway, catalyzing
                     the ring closure reaction of
                     1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate
                     (CdRP) to indole-3-glycerol phosphate (IGP), accompanied
                     by the...; Region: IGPS; cd00331"
                     /db_xref="CDD:238203"
     misc_feature    order(796058..796060,796064..796066,796073..796081,
                     796181..796183,796244..796246,796250..796252,
                     796313..796315,796391..796393,796454..796456,
                     796460..796462,796466..796468,796547..796552,
                     796613..796618)
                     /gene="trpC"
                     /locus_tag="COSY_0756"
                     /note="active site"
                     /db_xref="CDD:238203"
     misc_feature    order(796058..796060,796064..796066,796244..796246,
                     796391..796393,796454..796456)
                     /gene="trpC"
                     /locus_tag="COSY_0756"
                     /note="ribulose/triose binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238203"
     misc_feature    order(796064..796066,796550..796552,796613..796618)
                     /gene="trpC"
                     /locus_tag="COSY_0756"
                     /note="phosphate binding site [ion binding]; other site"
                     /db_xref="CDD:238203"
     misc_feature    order(796076..796078,796181..796183,796460..796462,
                     796466..796468)
                     /gene="trpC"
                     /locus_tag="COSY_0756"
                     /note="substrate (anthranilate) binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:238203"
     misc_feature    order(796181..796183,796244..796246,796250..796252,
                     796313..796315,796466..796468)
                     /gene="trpC"
                     /locus_tag="COSY_0756"
                     /note="product (indole) binding pocket [chemical binding];
                     other site"
                     /db_xref="CDD:238203"
     gene            796678..797091
                     /locus_tag="COSY_0757"
                     /db_xref="GeneID:5172483"
     CDS             796678..797091
                     /locus_tag="COSY_0757"
                     /note="redox protein regulator of disulfide bond
                     formation"
                     /codon_start=1
                     /transl_table=11
                     /product="redox protein regulator"
                     /protein_id="YP_001219589.1"
                     /db_xref="GI:148244895"
                     /db_xref="GeneID:5172483"
                     /translation="MNTTVKWINDMMIVGESDSGHAIVMDGPQNLGGKNLGIRPMEML
                     LLGIGGCTTIDVISTLKKMCQEVHTFRAEISSERAKEHPKIFTKIHIHFAIKGVNLND
                     KKVSKAVNLSTNKYCSALIILGKSATITHDFKIHK"
     misc_feature    796678..797082
                     /locus_tag="COSY_0757"
                     /note="OsmC-like protein; Region: OsmC; cl00767"
                     /db_xref="CDD:242076"
     gene            797611..797703
                     /locus_tag="COSY_t29"
                     /db_xref="GeneID:5329738"
     tRNA            797611..797703
                     /locus_tag="COSY_t29"
                     /product="tRNA-Ser"
                     /db_xref="GeneID:5329738"
     gene            797828..798607
                     /gene="thiG"
                     /locus_tag="COSY_0759"
                     /db_xref="GeneID:5172469"
     CDS             797828..798607
                     /gene="thiG"
                     /locus_tag="COSY_0759"
                     /note="functions in thiamine (vitamin B1) biosynthesis; in
                     Bacillus subtilis this enzyme catalyzes the formation of
                     thiazole from dehydroxyglycine and
                     1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate"
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="YP_001219590.1"
                     /db_xref="GI:148244896"
                     /db_xref="GeneID:5172469"
                     /translation="MIDIPLVIAKKTYNSRLLVGSGKYKDLNETKLATDMAEADIITV
                     AIRRTNIGQNVNEPNLLDIISPNKYTILPNTAGCYNAKDAIRTCQLARELLGGHNLIK
                     LEILGDKKTLYPNIVETLSAAKTLVDNGFDVMVYTSDDPIVAKELENIGCVAIMPLAS
                     LIGSGQGITNPTQIKLIKEHATVPVLIDAGIGCASDAAKAMELGCDGVLMNSAIANAN
                     NPILMASAMKNAIIAGRESFLSGRMMKKSYASASSPMVDLI"
     misc_feature    797843..798592
                     /gene="thiG"
                     /locus_tag="COSY_0759"
                     /note="Thiazole synthase (ThiG) is the tetrameric enzyme
                     that is involved in the formation of the thiazole moiety
                     of thiamin pyrophosphate, an essential ubiquitous cofactor
                     that plays an important role in carbohydrate and amino
                     acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728"
                     /db_xref="CDD:240079"
     misc_feature    order(797960..797962,798002..798004,798011..798013)
                     /gene="thiG"
                     /locus_tag="COSY_0759"
                     /note="ThiS interaction site; other site"
                     /db_xref="CDD:240079"
     misc_feature    order(798131..798133,798137..798139,798389..798391)
                     /gene="thiG"
                     /locus_tag="COSY_0759"
                     /note="putative active site [active]"
                     /db_xref="CDD:240079"
     misc_feature    order(798146..798148,798155..798157,798164..798172,
                     798239..798241,798245..798253,798260..798265,
                     798317..798325,798332..798334,798350..798352,
                     798362..798364,798404..798412,798422..798424,
                     798431..798436,798461..798463,798476..798484,
                     798491..798496,798503..798505,798524..798526,
                     798533..798538,798542..798556,798560..798565,
                     798569..798571,798575..798583,798587..798589)
                     /gene="thiG"
                     /locus_tag="COSY_0759"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240079"
     gene            799156..800253
                     /gene="bioF"
                     /locus_tag="COSY_0760"
                     /db_xref="GeneID:5172681"
     CDS             799156..800253
                     /gene="bioF"
                     /locus_tag="COSY_0760"
                     /EC_number="2.3.1.47"
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="YP_001219591.1"
                     /db_xref="GI:148244897"
                     /db_xref="GeneID:5172681"
                     /translation="MNFSQELSNLKQNYLYRTRKISKNTQISINGKSLINFCSNDYLS
                     LASHPQVKEAFKQGIDKFGVGASASHLISGHTATHQALEEALANYTGQEKALLFSTGY
                     MANIGVFSALKDKLNWVLQDKFNHASLIDANHLIGLPLQRYLHNNLKSLKKKINKQTG
                     QGLIVTENVFSMDGDQANIKGIEKIIEKTDTFLMQDDAHGFGVFKPIIPKNSIYMATL
                     GKAAGTMGAFVAGNEDLIDFLIQKSRPYIYTTAIIPALCSATLKSLELIKEGEQNTKL
                     LANIHYFQSLSKALNLPIKASNSAIQPLILGNNKKSINISKKLFSTGFHISAIRPPTV
                     PKNTARLRITLSANHTQNQIKQLLIQLKYVI"
     misc_feature    799162..800208
                     /gene="bioF"
                     /locus_tag="COSY_0760"
                     /note="8-amino-7-oxononanoate synthase; Reviewed; Region:
                     PRK05958"
                     /db_xref="CDD:235655"
     misc_feature    799168..800211
                     /gene="bioF"
                     /locus_tag="COSY_0760"
                     /note="pyridoxal phosphate-dependent acyltransferase,
                     putative; Region: gly_Cac_T_rel; TIGR01825"
                     /db_xref="CDD:130884"
     misc_feature    order(799456..799461,799468..799470,799654..799656,
                     799741..799743,799750..799752,799804..799806,
                     799813..799815)
                     /gene="bioF"
                     /locus_tag="COSY_0760"
                     /note="pyridoxal 5'-phosphate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:99742"
     misc_feature    799813..799815
                     /gene="bioF"
                     /locus_tag="COSY_0760"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99742"
     gene            800243..800980
                     /gene="bioH"
                     /locus_tag="COSY_0761"
                     /db_xref="GeneID:5172460"
     CDS             800243..800980
                     /gene="bioH"
                     /locus_tag="COSY_0761"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin biosynthesis protein BioH"
                     /protein_id="YP_001219592.1"
                     /db_xref="GI:148244898"
                     /db_xref="GeneID:5172460"
                     /translation="MLYSNTEGFGVDLVLLHGWGFNSKLFNSLFYNYKNQYRITLIDL
                     PGHGRSTNIDGGLNEWCDEIIKILPRNPILLGWSLGGLLAINIASKITVSSLILIAST
                     PNFIQTNNWEFGIDKNNFKQFSNALQLNLSKSLKRFISLQTKNKSKLKTLNKIIEQYS
                     TTTQALNQGLEILLNTNLNNKFKKLSIPIEVVLGKYDTLVPIKISHWYHQNNIKTCVL
                     NTGHLPFLHHDFALPSTLEVKYNPSNT"
     misc_feature    800273..800926
                     /gene="bioH"
                     /locus_tag="COSY_0761"
                     /note="pimelyl-[acyl-carrier protein] methyl ester
                     esterase; Region: bioH; TIGR01738"
                     /db_xref="CDD:130799"
     gene            800995..801483
                     /gene="purE"
                     /locus_tag="COSY_0762"
                     /db_xref="GeneID:5172480"
     CDS             800995..801483
                     /gene="purE"
                     /locus_tag="COSY_0762"
                     /EC_number="4.1.1.21"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase
                     catalytic subunit"
                     /protein_id="YP_001219593.1"
                     /db_xref="GI:148244899"
                     /db_xref="GeneID:5172480"
                     /translation="MSVLVGVIMGSKSDWITMKNTVNILKELSIPYEVKVISAHRTPD
                     LMFYYASNALKRGLKVIIAGAGGAAHLPGMVASKTIVPVLGVPIQSCALNGQDSLLSI
                     AQMPAGIPVGTLAIGKAGAKNAGILAAQIIGNENQTIRNIVTNFRAKQTQDILDNSNP
                     QE"
     misc_feature    800995..801480
                     /gene="purE"
                     /locus_tag="COSY_0762"
                     /note="Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
                     [Nucleotide transport and metabolism]; Region: PurE;
                     COG0041"
                     /db_xref="CDD:223119"
     gene            801487..802566
                     /gene="purK"
                     /locus_tag="COSY_0763"
                     /db_xref="GeneID:5172639"
     CDS             801487..802566
                     /gene="purK"
                     /locus_tag="COSY_0763"
                     /EC_number="4.1.1.21"
                     /note="With PurE catalyzes the conversion of
                     aminoimidazole ribonucleotide to carboxyaminoimidazole
                     ribonucleotide in the de novo purine nucleotide
                     biosynthetic pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase ATPase
                     subunit"
                     /protein_id="YP_001219594.1"
                     /db_xref="GI:148244900"
                     /db_xref="GeneID:5172639"
                     /translation="MKVGILGAGQLGRMLAISGYPLNHQFGFSGETHDEPSSLLGHMF
                     AHKDNINSLIEFSDVITYESENTKVEIIKKINKKVPVHPNEKSLFITQHRGREKALFN
                     QLNIPCAPYQMVNSESDLKAAIKTIGLPAILKTVTDGYDGKGQFLLHEAKQITKAWKS
                     MNDVESILEGFINFKRELSLIAVRGIDNSHKYYPIVENKHHKGILRLTIAPAQNINEK
                     IQKTAQYYMKTLLDEMDYIGVLTIELFETKNGLIVNEMAPRVHNSGHWSIEGTNTSQF
                     QNHIRAITGMPLGDTTPTHPFCAMINIISKLGDIDTVLKMPNTHLHLYDKSERKNRKL
                     GHTNITANSQAKLNESIAKLKNFLP"
     misc_feature    801487..802554
                     /gene="purK"
                     /locus_tag="COSY_0763"
                     /note="phosphoribosylaminoimidazole carboxylase ATPase
                     subunit; Reviewed; Region: PRK06019"
                     /db_xref="CDD:235674"
     misc_feature    801787..802296
                     /gene="purK"
                     /locus_tag="COSY_0763"
                     /note="ATP-grasp domain; Region: ATP-grasp; pfam02222"
                     /db_xref="CDD:216935"
     gene            complement(802574..802948)
                     /locus_tag="COSY_0764"
                     /db_xref="GeneID:5172196"
     CDS             complement(802574..802948)
                     /locus_tag="COSY_0764"
                     /note="glutaredoxin family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219595.1"
                     /db_xref="GI:148244901"
                     /db_xref="GeneID:5172196"
                     /translation="MRFLLKGFRNGLGAIIAFISWIVPVSKVKRTSEQQHKVDKETIN
                     IELYQFFGCPFCIKTRRMIKRLNLHIITRNAQTIGSKFRDEIQRETGKVQVPCLKITN
                     GDEVQWMFESNEISTYLNKHFR"
     misc_feature    complement(802580..802816)
                     /locus_tag="COSY_0764"
                     /note="Protein Disulfide Oxidoreductases and Other
                     Proteins with a Thioredoxin fold; Region:
                     Thioredoxin_like; cl00388"
                     /db_xref="CDD:241832"
     gene            complement(802945..803778)
                     /gene="folD"
                     /locus_tag="COSY_0765"
                     /db_xref="GeneID:5172456"
     CDS             complement(802945..803778)
                     /gene="folD"
                     /locus_tag="COSY_0765"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /note="catalyzes the formation of
                     5,10-methenyltetrahydrofolate from
                     5,10-methylenetetrahydrofolate and subsequent formation of
                     10-formyltetrahydrofolate from
                     5,10-methenyltetrahydrofolate"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/ 5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="YP_001219596.1"
                     /db_xref="GI:148244902"
                     /db_xref="GeneID:5172456"
                     /translation="MNVINGKKIAQNLQASIKLKVDTLDRKPGLAVILVGDDDASEVY
                     IRNKEDACKEVGFYLEIINRFDNISQEELLFEIERLNHDDKIDGILVQLPLPKHLDVN
                     LVIETISPKKDVDGFHSENIGKLMQNKPFLHPCTPKGVMLMLESIEIDLVGKNCVVVG
                     ASNIVGRPMACELLNAKATVTICNSKTKNLSCKLIQADIVVVAVGIPKMIQSDWIKPG
                     AIVIDVGINRLDNGCLVGDVDFESVRKVAGWIAPVPGGVGPMTIATLLKNTLTAYEAR
                     I"
     misc_feature    complement(802948..803778)
                     /gene="folD"
                     /locus_tag="COSY_0765"
                     /note="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/ 5,10-methylene-tetrahydrofolate
                     cyclohydrolase; Provisional; Region: PRK10792"
                     /db_xref="CDD:236760"
     misc_feature    complement(803434..803775)
                     /gene="folD"
                     /locus_tag="COSY_0765"
                     /note="Tetrahydrofolate dehydrogenase/cyclohydrolase,
                     catalytic domain; Region: THF_DHG_CYH; pfam00763"
                     /db_xref="CDD:201431"
     misc_feature    complement(802957..803451)
                     /gene="folD"
                     /locus_tag="COSY_0765"
                     /note="NADP binding domain of methylene-tetrahydrofolate
                     dehydrogenase/cyclohydrolase; Region:
                     NAD_bind_m-THF_DH_Cyclohyd; cd01080"
                     /db_xref="CDD:133448"
     misc_feature    complement(order(803191..803193,803218..803223,
                     803227..803229,803233..803250,803257..803259,
                     803266..803271,803296..803298,803314..803316,
                     803320..803322,803410..803412,803419..803424))
                     /gene="folD"
                     /locus_tag="COSY_0765"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:133448"
     misc_feature    complement(order(802996..802998,803005..803007,
                     803101..803103,803107..803109,803152..803154,
                     803161..803163,803167..803169,803224..803229,
                     803293..803298,803371..803373))
                     /gene="folD"
                     /locus_tag="COSY_0765"
                     /note="NADP binding site [chemical binding]; other site"
                     /db_xref="CDD:133448"
     misc_feature    complement(order(802993..802995,803014..803019))
                     /gene="folD"
                     /locus_tag="COSY_0765"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:133448"
     gene            complement(803782..804516)
                     /gene="kdsB"
                     /locus_tag="COSY_0766"
                     /db_xref="GeneID:5172010"
     CDS             complement(803782..804516)
                     /gene="kdsB"
                     /locus_tag="COSY_0766"
                     /EC_number="2.7.7.38"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="YP_001219597.1"
                     /db_xref="GI:148244903"
                     /db_xref="GeneID:5172010"
                     /translation="MNFSVIIPARYASSRLPAKLLRDVHGKPLIQLTYENAVNSGANR
                     VIIATDDKRIEVVANDFGAITCMTDGHFTSGTLRIAQVLEKLDINDDEIIVNVQGDEP
                     MLDPSVIDQVVNNLATNPMQIATLCKQITDKAQYFDPNCVKVVFNKIGKALYFSRATI
                     PFFREARDFDLKLCYKHIGVYAYRAGVIKQYLTMNSSSYEKVEKLEQLTALNEGFDIH
                     VAPACASVGHGVDIQRDLDEVRKELG"
     misc_feature    complement(803788..804516)
                     /gene="kdsB"
                     /locus_tag="COSY_0766"
                     /note="3-deoxy-manno-octulosonate cytidylyltransferase;
                     Provisional; Region: PRK05450"
                     /db_xref="CDD:235473"
     misc_feature    complement(803794..804513)
                     /gene="kdsB"
                     /locus_tag="COSY_0766"
                     /note="CMP-KDO synthetase catalyzes the activation of KDO
                     which is an essential component of the lipopolysaccharide;
                     Region: CMP-KDO-Synthetase; cd02517"
                     /db_xref="CDD:133010"
     misc_feature    complement(order(804217..804219,804223..804225,
                     804292..804294,804373..804375,804487..804495))
                     /gene="kdsB"
                     /locus_tag="COSY_0766"
                     /note="Ligand binding site; other site"
                     /db_xref="CDD:133010"
     misc_feature    complement(order(803875..803886,803905..803913,
                     803920..803925,803998..804000,804031..804051,
                     804055..804060,804076..804084,804100..804102,
                     804151..804153))
                     /gene="kdsB"
                     /locus_tag="COSY_0766"
                     /note="oligomer interface; other site"
                     /db_xref="CDD:133010"
     gene            complement(804516..804695)
                     /locus_tag="COSY_0767"
                     /db_xref="GeneID:5172725"
     CDS             complement(804516..804695)
                     /locus_tag="COSY_0767"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219598.1"
                     /db_xref="GI:148244904"
                     /db_xref="GeneID:5172725"
                     /translation="MIDEALLKLLVCPKSKAPLKQVGNELICEVSGLAYPIEDGIPIL
                     LVEEARELDKGSDKK"
     misc_feature    complement(804537..804692)
                     /locus_tag="COSY_0767"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG2835"
                     /db_xref="CDD:225391"
     gene            complement(804692..805639)
                     /gene="lpxK"
                     /locus_tag="COSY_0768"
                     /db_xref="GeneID:5172452"
     CDS             complement(804692..805639)
                     /gene="lpxK"
                     /locus_tag="COSY_0768"
                     /EC_number="2.7.1.130"
                     /note="transfers the gamma-phosphate of ATP to the 4'
                     position of a tetraacyldisaccharide 1-phosphate
                     intermediate to form tetraacyldisaccharide
                     1,4'-bis-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="YP_001219599.1"
                     /db_xref="GI:148244905"
                     /db_xref="GeneID:5172452"
                     /translation="MDLNTRGIINYLLLPISGIFYLASVLRKWLYQVNFFKVKKFKCP
                     VIVVGNITVGGTGKTPIVILLAQYFKQQGKQVGVVLRGYGGMHHKGSLLVSKNTNVYL
                     SGDEPLLIALQADLPVMVNRNRAQAVEDLINQCQVNLIISDDGLQHYRMDRNIEIAVI
                     DGTRRFGNEFFLPSGPLRESIDRLKSVDFVINNAGFRAGEFNIKLILKVFVNVKTGEE
                     KPLDYFNGEYCHGVAGIGYPQRFFDTLIRLGINLKPHIFADHYVYQQSDLVFEDNYPI
                     LMTAKDCVKCIQFANNQMWYLQVEANLSDNFFKELEAKL"
     misc_feature    complement(804695..805627)
                     /gene="lpxK"
                     /locus_tag="COSY_0768"
                     /note="tetraacyldisaccharide 4&apos;-kinase; Reviewed;
                     Region: lpxK; PRK00652"
                     /db_xref="CDD:234808"
     misc_feature    complement(804728..805615)
                     /gene="lpxK"
                     /locus_tag="COSY_0768"
                     /note="tetraacyldisaccharide 4&apos;-kinase; Region: lpxK;
                     TIGR00682"
                     /db_xref="CDD:233090"
     gene            806066..807301
                     /gene="lolE"
                     /locus_tag="COSY_0769"
                     /db_xref="GeneID:5172094"
     CDS             806066..807301
                     /gene="lolE"
                     /locus_tag="COSY_0769"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein ABC transporter permease LolE"
                     /protein_id="YP_001219600.1"
                     /db_xref="GI:148244906"
                     /db_xref="GeneID:5172094"
                     /translation="MSIEFIISNQYLRSNQKKGFISFIPGVSIVGLILSVVTLITVLS
                     VMNGFHKELRDRVLNTISHSYITQYNNLVDNWQNLQTKINKHPNVVSTSPYIEKYALL
                     STHNGTQGVNVRGIRPNLEKKTSILLDKIKSGNANLLKSDILIGTGLATQLGLIIGDK
                     ITLLTPKLSSNIIGIQPRFKRFTISGIFDAGISEYDNNLAFISLEQAQKLYIMKDKVS
                     GIRLKVDDLFNAKKITNEIITNLLDGRYYGIDWTEQKANFIKALNLEKQMISIIMSLI
                     IAVAAFNIVSMIVMVVNDRKADIAILRTLGMTPNRIVKIFLYQGLIIGLIGITIGSIL
                     GVLLSLNIEMIVSGIESILGFQFFPKDLFYISRFPSEIHIIDIVKVIFGGFILITIAS
                     IYPAKLAGKIDIAKVLNHE"
     misc_feature    806069..807298
                     /gene="lolE"
                     /locus_tag="COSY_0769"
                     /note="lipoprotein releasing system, transmembrane
                     protein, LolC/E family; Region: lolCE; TIGR02212"
                     /db_xref="CDD:233781"
     misc_feature    <806309..806776
                     /gene="lolE"
                     /locus_tag="COSY_0769"
                     /note="MacB-like periplasmic core domain; Region:
                     MacB_PCD; pfam12704"
                     /db_xref="CDD:221725"
     misc_feature    806873..807277
                     /gene="lolE"
                     /locus_tag="COSY_0769"
                     /note="FtsX-like permease family; Region: FtsX; pfam02687"
                     /db_xref="CDD:217187"
     gene            807294..807968
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /db_xref="GeneID:5172527"
     CDS             807294..807968
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein ABC transporter ATP-binding protein
                     LolD"
                     /protein_id="YP_001219601.1"
                     /db_xref="GI:148244907"
                     /db_xref="GeneID:5172527"
                     /translation="MNNIIECNNISYTYFNGKQKIPILNNLNLNVKQGESIAILGQSG
                     CGKSTLLNLLGGIDKPTQGKILINGINLNTLNENDTTLLRGKYLGFVYQFHHLLNDFS
                     MLDNVAMPERIQGVNQKSAQANAKKLLSKIGLEHRLNHLPSELSGGERQRVAIARALI
                     TNPSCILADEPTGNLDAKNTNEILNLMLELNHDQNCALIIVTHDEKIAIKMDKSLILN
                     HGILTT"
     misc_feature    807303..807962
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /note="lipoprotein releasing system, ATP-binding protein;
                     Region: LolD_lipo_ex; TIGR02211"
                     /db_xref="CDD:131266"
     misc_feature    807306..807953
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /note="ATP-binding cassette domain of the transporters
                     involved in export of lipoprotein and macrolide, and cell
                     division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255"
                     /db_xref="CDD:213222"
     misc_feature    807414..807437
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213222"
     misc_feature    order(807423..807428,807432..807440,807570..807572,
                     807798..807803,807900..807902)
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213222"
     misc_feature    807561..807572
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213222"
     misc_feature    807726..807755
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213222"
     misc_feature    807786..807803
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /note="Walker B; other site"
                     /db_xref="CDD:213222"
     misc_feature    807810..807821
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /note="D-loop; other site"
                     /db_xref="CDD:213222"
     misc_feature    807888..807908
                     /gene="lolD"
                     /locus_tag="COSY_0770"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213222"
     gene            complement(808390..808773)
                     /gene="panD"
                     /locus_tag="COSY_0771"
                     /db_xref="GeneID:5172468"
     CDS             complement(808390..808773)
                     /gene="panD"
                     /locus_tag="COSY_0771"
                     /EC_number="4.1.1.11"
                     /note="Converts L-aspartate to beta-alanine and provides
                     the major route of beta-alanine production in bacteria.
                     Beta-alanine is essential for the biosynthesis of
                     pantothenate (vitamin B5)"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate alpha-decarboxylase"
                     /protein_id="YP_001219602.1"
                     /db_xref="GI:148244908"
                     /db_xref="GeneID:5172468"
                     /translation="MKRIFLSAKLHKVTTTAVELNYEGSCEIDGVLLDAAGIGAFEQI
                     QIYNINNGNRFTTYTILGKDNSGIISVNGAAARKVNVGDVLIIAAYALYSEEELEGYA
                     PRLCYVNNKNILTKISTGSKKSSLY"
     misc_feature    complement(808438..808770)
                     /gene="panD"
                     /locus_tag="COSY_0771"
                     /note="Aspartate alpha-decarboxylase or L-aspartate
                     1-decarboxylase, a pyruvoyl group-dependent  decarboxylase
                     in beta-alanine production; Region: Asp_decarbox; cd06919"
                     /db_xref="CDD:132994"
     misc_feature    complement(order(808471..808473,808498..808506,
                     808516..808518,808540..808545,808549..808554,
                     808600..808614,808618..808620,808627..808629,
                     808633..808635,808645..808650,808657..808659,
                     808663..808665,808705..808716,808738..808743,
                     808747..808749,808753..808770))
                     /gene="panD"
                     /locus_tag="COSY_0771"
                     /note="tetramerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:132994"
     misc_feature    complement(order(808600..808602,808699..808704,
                     808741..808743,808747..808749))
                     /gene="panD"
                     /locus_tag="COSY_0771"
                     /note="active site"
                     /db_xref="CDD:132994"
     gene            complement(808783..809913)
                     /gene="oadB"
                     /locus_tag="COSY_0772"
                     /db_xref="GeneID:5171884"
     CDS             complement(808783..809913)
                     /gene="oadB"
                     /locus_tag="COSY_0772"
                     /EC_number="4.1.1.3"
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase, beta subunit"
                     /protein_id="YP_001219603.1"
                     /db_xref="GI:148244909"
                     /db_xref="GeneID:5171884"
                     /translation="MEQLNTLWINTGLHQMSWGQGLMLLVGILLLYLAIVKNFEPLLL
                     LPIGFGSILANIPGAGIAEGSGILHIFYVIGIESGAFPLIIFMGVGALTDFGPLLANP
                     KTLLLGAAAQFGIFATLLGAIGLTVVGIFDFSLTDAAAIGIIGGADGPTSIYVASKLA
                     PDLLGAIAVASYSYMALVPLIQPPIMRALTTKKERQIEMVQLRKVSKYEKIIFPIMLL
                     MLVALLLPDAAPLLGMFAFGNLMKESGVVNRLSDTMQNALINIVTIFLGLAVGSKLMA
                     EKFLQLDTLGILLLGMVAFAIGTACGVLMAKCMNIFSKNKINPLIGSAGVSAVPMAAR
                     VSNKVGLEANPHNFLLMHAMGPNVAGVIGSAIAAGIMIQFLG"
     misc_feature    complement(808840..809913)
                     /gene="oadB"
                     /locus_tag="COSY_0772"
                     /note="Na+-transporting methylmalonyl-CoA/oxaloacetate
                     decarboxylase, beta subunit [Energy production and
                     conversion]; Region: OadB; COG1883"
                     /db_xref="CDD:224795"
     gene            complement(809928..811700)
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /db_xref="GeneID:5171897"
     CDS             complement(809928..811700)
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /EC_number="4.1.1.3"
                     /note="catalyzes the formation of pyruvate from
                     oxaloacetate"
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase"
                     /protein_id="YP_001219604.1"
                     /db_xref="GI:148244910"
                     /db_xref="GeneID:5171897"
                     /translation="MEITELVFRDGHQSLFATRMRIDDMLPIADKLDKIGYWSIESWG
                     GATFDSCIRYLGEDPWDRIREIKKVMPNTPQQMLLRGQNLLGYRHYSDDVVRKFVDQS
                     AKNGVSIFRIFDAMNDIRNLKTATDQAVKIGQHAQGTLSYTISPVHNIQTWLDMAREI
                     EDMGAHSLCIKDMAGLLQPYVAYDLIKALKMVVDIPIQLHAHATTGLSTATIVKAVEA
                     GIDRVDTAIGSMSMTYGHSATNSVVSILENSPRKTGLDLKKLEEIDSYFRSVRCKYTH
                     FEGSLKGVDSRILLSQVPGGMLTNMESQLREQGALDKMDEVLVEIACVRKDLGYIPLV
                     TPTSQIVGTQSVLNVLTGERYKTITKESAGVLKGEYGATPAPVDQALQFKVLDGGEPI
                     TCRPADNIAPEMQILEKEFDRIVAKKGIILAKGKIDDLLTYALFPQVGILFLQNRDNP
                     DFFEPVSQIVESCQRSDKKEETYTVSFKGNSYTVDVSAGGDITSMKASYDQTKLSTPV
                     EKEILSIAPTTKGEVIGAPLSGTIWKVIVEVNQKIAQGDVLVILEAMKMETEIKAARS
                     GVVTDIEIKEGDTVDVGQTLLILV"
     misc_feature    complement(809931..811700)
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /note="oxaloacetate decarboxylase; Provisional; Region:
                     PRK14040"
                     /db_xref="CDD:237592"
     misc_feature    complement(810870..811694)
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /note="Pyruvate carboxylase and Transcarboxylase 5S,
                     carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S;
                     cd07937"
                     /db_xref="CDD:163675"
     misc_feature    complement(order(810993..810995,811095..811097,
                     811101..811103,811188..811190,811278..811280,
                     811461..811463,811467..811469,811566..811568,
                     811578..811580,811662..811664,811671..811676))
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /note="active site"
                     /db_xref="CDD:163675"
     misc_feature    complement(order(811578..811580,811671..811676))
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:163675"
     misc_feature    complement(order(811095..811097,811101..811103,
                     811188..811190,811671..811673))
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163675"
     misc_feature    complement(order(810918..810920,810960..810962,
                     810978..810980,811008..811010,811014..811019,
                     811059..811064,811074..811076,811080..811082,
                     811086..811088,811161..811163,811167..811169))
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /note="homodimer binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:163675"
     misc_feature    complement(809934..810134)
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /note="The biotinyl-domain or biotin carboxyl carrier
                     protein (BCCP) domain is present in all biotin-dependent
                     enzymes, such as acetyl-CoA carboxylase, pyruvate
                     carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA
                     carboxylase, geranyl-CoA carboxylase; Region:
                     biotinyl_domain; cd06850"
                     /db_xref="CDD:133459"
     misc_feature    complement(order(810009..810011,810030..810038,
                     810063..810065))
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /note="carboxyltransferase (CT) interaction site; other
                     site"
                     /db_xref="CDD:133459"
     misc_feature    complement(810033..810035)
                     /gene="oadA"
                     /locus_tag="COSY_0773"
                     /note="biotinylation site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133459"
     gene            complement(812023..812107)
                     /locus_tag="COSY_t30"
                     /db_xref="GeneID:5329740"
     tRNA            complement(812023..812107)
                     /locus_tag="COSY_t30"
                     /product="tRNA-Leu"
                     /db_xref="GeneID:5329740"
     gene            complement(812116..812334)
                     /gene="infA"
                     /locus_tag="COSY_0775"
                     /db_xref="GeneID:5171900"
     CDS             complement(812116..812334)
                     /gene="infA"
                     /locus_tag="COSY_0775"
                     /note="stimulates the activities of the other two
                     initiation factors, IF-2 and IF-3"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="YP_001219605.1"
                     /db_xref="GI:148244911"
                     /db_xref="GeneID:5171900"
                     /translation="MSKSDYIELEGFVKEKLPNTTFMVELENGHCILAHISGKIRKHY
                     IRILPGDKVTVEMTPYDLTKGRITFRHK"
     misc_feature    complement(812125..812316)
                     /gene="infA"
                     /locus_tag="COSY_0775"
                     /note="S1_IF1: Translation Initiation Factor IF1, S1-like
                     RNA-binding domain. IF1 contains an S1-like RNA-binding
                     domain, which is found in a wide variety of RNA-associated
                     proteins. Translation initiation includes a number of
                     interrelated steps preceding the...; Region: S1_IF1;
                     cd04451"
                     /db_xref="CDD:239898"
     misc_feature    complement(order(812137..812139,812143..812145,
                     812194..812205,812218..812223,812230..812232,
                     812266..812268,812284..812292))
                     /gene="infA"
                     /locus_tag="COSY_0775"
                     /note="rRNA binding site [nucleotide binding]; other site"
                     /db_xref="CDD:239898"
     misc_feature    complement(order(812125..812127,812218..812220,
                     812230..812232))
                     /gene="infA"
                     /locus_tag="COSY_0775"
                     /note="predicted 30S ribosome binding site; other site"
                     /db_xref="CDD:239898"
     gene            812501..813322
                     /gene="metF"
                     /locus_tag="COSY_0776"
                     /db_xref="GeneID:5172579"
     CDS             812501..813322
                     /gene="metF"
                     /locus_tag="COSY_0776"
                     /EC_number="1.5.1.20"
                     /note="methylenetetrahydrofolate reductase (NADPH)"
                     /codon_start=1
                     /transl_table=11
                     /product="5,10-methylenetetrahydrofolate reductase"
                     /protein_id="YP_001219606.1"
                     /db_xref="GI:148244912"
                     /db_xref="GeneID:5172579"
                     /translation="MKISFEFFPPKTEQGKEKLIQVRQSLSVVSPKYFSTTSGAGGTT
                     QDTTLETVLDIQKNNNIPATPHLSCIGLKKSNIIELLDKYKAININHIIALRGDIPSS
                     IRNMGDFNYANELVEFIRSKYNDNFNIEVAAYPEMHPQAKNIKSDLTHFVNKVKAGAN
                     GAITQYFYNADAYFRFQDDVQKLGINIPITPGIMPITNYTKLLNFSNMCGAQIPKWIL
                     ERLKFYENDLESLNDFGFDVVANLCQTLKNQGVNSFHFYSMNLVEPSLKLAKNII"
     misc_feature    812507..813316
                     /gene="metF"
                     /locus_tag="COSY_0776"
                     /note="Methylenetetrahydrofolate reductase (MTHFR).
                     5,10-Methylenetetrahydrofolate is reduced to
                     5-methyltetrahydrofolate by methylenetetrahydrofolate
                     reductase, a cytoplasmic, NAD(P)-dependent enzyme.
                     5-methyltetrahydrofolate is utilized by methionine
                     synthase...; Region: MTHFR; cd00537"
                     /db_xref="CDD:238299"
     misc_feature    order(812612..812614,812696..812698,812783..812791,
                     812831..812836,812894..812896,812900..812902,
                     812912..812914,812918..812920,812939..812941,
                     812948..812950,812957..812962,812987..812989,
                     812993..812995,813269..813271)
                     /gene="metF"
                     /locus_tag="COSY_0776"
                     /note="FAD binding site [chemical binding]; other site"
                     /db_xref="CDD:238299"
     gene            complement(813334..813798)
                     /locus_tag="COSY_0777"
                     /db_xref="GeneID:5172202"
     CDS             complement(813334..813798)
                     /locus_tag="COSY_0777"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219607.1"
                     /db_xref="GI:148244913"
                     /db_xref="GeneID:5172202"
                     /translation="MVLWRASVIKLSVSQAARKLGVSRAHIQTQINLGKLQTHEGYVT
                     TDSIRLAYPKISLYSEQDKYIQKMQQIKSDAMFKAGVADLTKQENEEKLINIVTALKS
                     KLYKEELRNEHYVMVFEELYSRLNIFEKCCHTQDKESLHKLQYWIKIQSNLN"
     gene            complement(813816..814562)
                     /gene="hemD"
                     /locus_tag="COSY_0778"
                     /db_xref="GeneID:5172430"
     CDS             complement(813816..814562)
                     /gene="hemD"
                     /locus_tag="COSY_0778"
                     /EC_number="4.2.1.75"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthetase"
                     /protein_id="YP_001219608.1"
                     /db_xref="GI:148244914"
                     /db_xref="GeneID:5172430"
                     /translation="MNVMLTRPALQVEKLQDMVVKSGNNPLFFPTLKLHPIDIKLEKN
                     HYDVIIFISANAVEYGLKILKNISYQQVLAVGSATAKKLSENNIIINDFPKNKASSEA
                     LLELDSVTQLNDKTILIFRGKGGRETLKQGLIKQGNQVEYVEVYERVCCDISHLHCQS
                     LDKFLLSREGVISITSIDNMKSLIKIVNQINHIDKLKNYLLVVLSERIKIYVNSIEFD
                     KVLVTPNTSNNGIISVLMNLNTLDKPVKYS"
     misc_feature    complement(813858..814562)
                     /gene="hemD"
                     /locus_tag="COSY_0778"
                     /note="uroporphyrinogen-III synthase; Reviewed; Region:
                     hemD; PRK05928"
                     /db_xref="CDD:235647"
     misc_feature    complement(813858..814556)
                     /gene="hemD"
                     /locus_tag="COSY_0778"
                     /note="Uroporphyrinogen-III synthase (HemD) catalyzes the
                     asymmetrical cyclization of tetrapyrrole (linear) to
                     uroporphyrinogen-III, the fourth step in the biosynthesis
                     of heme. This ubiquitous enzyme is present in eukaryotes,
                     bacteria and archaea. Mutations in...; Region: HemD;
                     cd06578"
                     /db_xref="CDD:119440"
     misc_feature    complement(order(814026..814040,814119..814121,
                     814125..814127,814197..814199,814329..814331,
                     814398..814406,814542..814544))
                     /gene="hemD"
                     /locus_tag="COSY_0778"
                     /note="active site"
                     /db_xref="CDD:119440"
     gene            complement(814566..815159)
                     /locus_tag="COSY_0779"
                     /db_xref="GeneID:5172640"
     CDS             complement(814566..815159)
                     /locus_tag="COSY_0779"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219609.1"
                     /db_xref="GI:148244915"
                     /db_xref="GeneID:5172640"
                     /translation="MNKTEFLIGRSDLDLLDDFYPDDLPNEWRFDYYSTLFKALSLKI
                     DTKEDLEQIFIELKESDEVFELVVYIEQTQLLEISMLKLLLKPIHQYRSRFNLFCELD
                     EQPSNEVMKILSGYKLCFQSDNKLKFDLNTKLITNKYFYFTQFPILYTSNIWDEKQIR
                     RFLQDVSLVNTKIILICKYAESETLNKIRIIAEILGF"
     gene            815220..816173
                     /locus_tag="COSY_0780"
                     /db_xref="GeneID:5172416"
     CDS             815220..816173
                     /locus_tag="COSY_0780"
                     /note="Ca2+:cation antiporter (CaCA) family"
                     /codon_start=1
                     /transl_table=11
                     /product="Ca2+:Na+ antiporter"
                     /protein_id="YP_001219610.1"
                     /db_xref="GI:148244916"
                     /db_xref="GeneID:5172416"
                     /translation="MPDILLPIIALLSGFTLLIWSADKFTENGVKIANIFRISPFIIG
                     IIILGFGTSIPEILVSTLAAIKGNTGLSIGNAIGSNISNISLILGISAIISPINVQWK
                     ILKKEWLFLMITTLCAGLLLWDYRLDFKDGLILLSLLVLFFAYIFKQAKNKTHHNFNE
                     VKHNTNKDQIKKTKIILIISLTILVSSAELVAWGGIEVAKIFGISDLIIGLSIIALGT
                     SLPELAVSISSVLKKQYTMVVGNVIGSNIFNIIAVLAIPGLIHPSDVPIEVINRDYPV
                     MLLLTILLFVVSYKFNKKHIINRLEGFFLIGIFSLYMWQLL"
     misc_feature    815220..816158
                     /locus_tag="COSY_0780"
                     /note="Ca2+/Na+ antiporter [Inorganic ion transport and
                     metabolism]; Region: ECM27; COG0530"
                     /db_xref="CDD:223604"
     misc_feature    <815880..816161
                     /locus_tag="COSY_0780"
                     /note="Sodium/calcium exchanger protein; Region: Na_Ca_ex;
                     pfam01699"
                     /db_xref="CDD:216653"
     gene            816158..816625
                     /locus_tag="COSY_0781"
                     /db_xref="GeneID:5172395"
     CDS             816158..816625
                     /locus_tag="COSY_0781"
                     /note="putative nucleotide-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219611.1"
                     /db_xref="GI:148244917"
                     /db_xref="GeneID:5172395"
                     /translation="MAIIMKLTLHNESDTYEFAHQLAQCTQLVNSCIVIYLEGDLGVG
                     KTTFARGFIQFYGFDQVKSPTYSLVESYINDKVNIHHFDCYRLGDAQELEYIGIREYL
                     APGHIQLIEWAELGKGMIAPTDMIIRITDHLDKHELQITTHTQVGNQLLACIN"
     misc_feature    816170..816613
                     /locus_tag="COSY_0781"
                     /note="Predicted ATPase or kinase [General function
                     prediction only]; Region: COG0802"
                     /db_xref="CDD:223873"
     gene            complement(817196..817537)
                     /gene="dsrR"
                     /locus_tag="COSY_0782"
                     /db_xref="GeneID:5172350"
     CDS             complement(817196..817537)
                     /gene="dsrR"
                     /locus_tag="COSY_0782"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrR"
                     /protein_id="YP_001219612.1"
                     /db_xref="GI:148244918"
                     /db_xref="GeneID:5172350"
                     /translation="MIIITKKASDEIILSTHNPENKGLLIRFSVDKTNDGFQYFMGFD
                     DRNDSDIHLESNGIEYIFAYEQKILLEGMVVDFDQIDKNSDYHFVFMNPNDPNYEPPE
                     KECAPDKLNKK"
     misc_feature    complement(817256..817537)
                     /gene="dsrR"
                     /locus_tag="COSY_0782"
                     /note="Iron-sulphur cluster biosynthesis; Region:
                     Fe-S_biosyn; cl00400"
                     /db_xref="CDD:241842"
     gene            complement(817534..818910)
                     /gene="dsrN"
                     /locus_tag="COSY_0783"
                     /db_xref="GeneID:5172432"
     CDS             complement(817534..818910)
                     /gene="dsrN"
                     /locus_tag="COSY_0783"
                     /note="Similar to cobyrinic acid a, c-diamide synthase
                     CbiA."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrN"
                     /protein_id="YP_001219613.1"
                     /db_xref="GI:148244919"
                     /db_xref="GeneID:5172432"
                     /translation="MPLSFYLSAAHKSSGKTVISLGLCAAFKQKSLNVQTFKKGPDYI
                     DPIWLSKASGNPCYNLDFYNMTDNEIIQLYQNQSLNSDIDIIEGNKGLFDGMSVAGGD
                     ANADLAKLLMTPVILVIDSTGITRGVAPLLSGYQVFDKEINIAGVILNKVASERHESK
                     LIQAINYYTDIPVLGCIRRSKALIIDERHLGLIPVNETPQSQTFIKKVTNIITDQVDL
                     NTLVDFNCIKSNKKIINTYTNINTIKEKIIIAIAKDAVFNFYYQDDLDKFESLGVKIK
                     YFDTLKDNNLPICDGLFIGGGFPEMQLEALNANQSLLVDIKTKIEQDLPTYVECGGLM
                     YLTNSITHNKKTYSMMGVIDADTYMMSKPVGRGYVELEPTDKHCWAGVSKHIYAHEFH
                     YSKLKNISSNTRYAFNVLRGVGVNNKFDGIMKYNLLASYTHLHNVANNAWVIQFVNFI
                     NKVKKQEL"
     misc_feature    complement(818368..818910)
                     /gene="dsrN"
                     /locus_tag="COSY_0783"
                     /note="The Fer4_NifH superfamily contains a variety of
                     proteins which share a common ATP-binding domain.
                     Functionally, proteins in this superfamily use the energy
                     from hydrolysis of NTP to transfer electron or ion;
                     Region: Fer4_NifH; cl17203"
                     /db_xref="CDD:247757"
     misc_feature    complement(817564..818898)
                     /gene="dsrN"
                     /locus_tag="COSY_0783"
                     /note="Cobyrinic acid a,c-diamide synthase [Coenzyme
                     metabolism]; Region: CobB; COG1797"
                     /db_xref="CDD:224710"
     misc_feature    complement(817570..818151)
                     /gene="dsrN"
                     /locus_tag="COSY_0783"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in Cobyrinic Acid a,c-Diamide Synthase; Region:
                     GATase1_CobB; cd03130"
                     /db_xref="CDD:153224"
     misc_feature    complement(order(817600..817602,817606..817608,
                     817921..817923))
                     /gene="dsrN"
                     /locus_tag="COSY_0783"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153224"
     gene            complement(818938..820140)
                     /gene="dsrP"
                     /locus_tag="COSY_0784"
                     /db_xref="GeneID:5172402"
     CDS             complement(818938..820140)
                     /gene="dsrP"
                     /locus_tag="COSY_0784"
                     /note="polysulphide reductase/molybdopterin oxidoreductase
                     membrane subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrP"
                     /protein_id="YP_001219614.1"
                     /db_xref="GI:148244920"
                     /db_xref="GeneID:5172402"
                     /translation="MSNIRFEQIEGKSLGFYILITGLGILILAALGSVYYVEHHGHFV
                     TGMNNRIVWGMPHVFALFLIVAASGALNVASISSVFNKKLYKPLSRLSGLVALSLLAG
                     GLMVLVLDLGRIDRLIVAMTEYNFKSIFAWNIILYNGFFVVVAIYLWMMFERRMNKFS
                     HKVGLVAFSWRLILTTGTGSIFGFLVARQAYDAVIMAPMFIIMSFSFGLASFILILMA
                     SYKWTNRPLGNIIVNRLRNLLGVFVAAVMYFVAVYHLGNLYLAENTGIENFILFDGGI
                     YTKLFWYGQIILGGIVPMVLIYHPITKGDRSMLGLSSVLIIIGGFIQLYVIIIGGQAY
                     PMELFPGKEVLEGYGDIAQYLVSLPEVFLGIGGIALAIIIVTFLVKFLAFLPESLEDD
                     LADLYYKR"
     misc_feature    complement(818959..820041)
                     /gene="dsrP"
                     /locus_tag="COSY_0784"
                     /note="Polysulphide reductase [Energy production and
                     conversion]; Region: COG5557; cl17901"
                     /db_xref="CDD:248455"
     misc_feature    complement(819136..820011)
                     /gene="dsrP"
                     /locus_tag="COSY_0784"
                     /note="Polysulphide reductase, NrfD; Region: NrfD;
                     pfam03916"
                     /db_xref="CDD:217790"
     gene            complement(820166..820897)
                     /gene="dsrO"
                     /locus_tag="COSY_0785"
                     /db_xref="GeneID:5172419"
     CDS             complement(820166..820897)
                     /gene="dsrO"
                     /locus_tag="COSY_0785"
                     /note="iron-sulfur binding protein/polysulfide reductase
                     subunit B/molybdopterin oxidoreductase iron-sulfur binding
                     subunit."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrO"
                     /protein_id="YP_001219615.1"
                     /db_xref="GI:148244921"
                     /db_xref="GeneID:5172419"
                     /translation="MNKALNRRDFIKIMNATTTGVAIVASGITLTTFASVSETPVTNK
                     KRWGLLIDTNKLTETDIDGMVNACQQEQGWGTEIRSTSSQKPGWIKKLKIKDKATNKV
                     SNLALMCQHCEEPPCVDVCPTNASMKREDGIVLVDKHLCIGCRYCMMACPYDARSFVH
                     ETLNNQKEHMPRGKGTVEACTMCVHKVDKGETPACVESVNSEAVIFGNLYDESSQINQ
                     TLKIVQSSQIRADLNLNTGVRYSGI"
     misc_feature    complement(820178..820789)
                     /gene="dsrO"
                     /locus_tag="COSY_0785"
                     /note="Fe-S-cluster-containing hydrogenase components 1
                     [Energy production and conversion]; Region: HybA; COG0437"
                     /db_xref="CDD:223514"
     misc_feature    complement(820433..820501)
                     /gene="dsrO"
                     /locus_tag="COSY_0785"
                     /note="4Fe-4S binding domain; Region: Fer4_6; pfam12837"
                     /db_xref="CDD:205098"
     gene            complement(820894..821277)
                     /gene="dsrJ"
                     /locus_tag="COSY_0786"
                     /db_xref="GeneID:5172414"
     CDS             complement(820894..821277)
                     /gene="dsrJ"
                     /locus_tag="COSY_0786"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrJ"
                     /protein_id="YP_001219616.1"
                     /db_xref="GI:148244922"
                     /db_xref="GeneID:5172414"
                     /translation="MNRFLVVFLSLLVSSVFAYIDEYANLGEQASSIKASGKVFHESP
                     SIIRKMHPEFLRHKRDKTLRQGIRTNEYSLKGCVSCHANKNKINNQYYSVDKQGQFCS
                     DCHKKVGVSFDCFSCHRTVLREDLL"
     gene            complement(821307..823271)
                     /gene="dsrL"
                     /locus_tag="COSY_0787"
                     /db_xref="GeneID:5172337"
     CDS             complement(821307..823271)
                     /gene="dsrL"
                     /locus_tag="COSY_0787"
                     /note="unknown function"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glutamate synthase (NADPH) small
                     subunit"
                     /protein_id="YP_001219617.1"
                     /db_xref="GI:148244923"
                     /db_xref="GeneID:5172337"
                     /translation="MQKNPYGVPTKSDNHTFRLYTNDGDEQKTVPWSQKIFKEDTSHK
                     CPTYVTQTPPCQGSCPSGHNVRGWLDIVRGMEKPSGELSWQEYAFQRSTDSNPFPSIM
                     GRVCPAPCEDGCNRNEVENTVGINAVEQFIGDNAKVEGYTFTINAKDTGKKVAIIGGG
                     CGGLTTALKLRRQGHSVTIFEKYDQLGGMMMYGIPDYRVPRDVLSYEIDRIINTGIET
                     RMNTKVGIDVTIDELEKKFDAVLFAIGAMSGRTLPIPGGKATNCVSGIAFLEAYNQGR
                     LKHITGKVICIGGGDTSIDVVSVARRLGNINNAAEKDRPEHIIFSDTTHDVVDTSKRL
                     GADVLLTTRSTVVNMPAAQEEIDDATREGVEIQGQLQPVEVITGKDGRATALRMIRLE
                     EDGSTPIKGSEFEIECELIVSAIGQGVDSEGIDISFFNKHGFINADKNYQVPNKPGFF
                     VCGDVIRPHLLTTAIGQASVVAESIGDYLSGFEQHTRPKVDVSYFDLMEKLKEWDLAP
                     ESYKSGSNVATATDSANFAVHNYEDRAFASIIPHTELFLGHFDHEQHNQRNHKLVDVD
                     NVLGNFNERLIGYTEKEAQKEAARCMSCGLCFECDNCVMYCPQDAVFKVKKDKATLGR
                     YVDTDYNKCIGCHICADVCPTGYIQMGLGE"
     misc_feature    complement(821310..823250)
                     /gene="dsrL"
                     /locus_tag="COSY_0787"
                     /note="putative glutamate synthase (NADPH) small subunit;
                     Provisional; Region: PRK12771"
                     /db_xref="CDD:237198"
     misc_feature    complement(<822672..822806)
                     /gene="dsrL"
                     /locus_tag="COSY_0787"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; pfam13450"
                     /db_xref="CDD:205628"
     misc_feature    complement(<821334..>821534)
                     /gene="dsrL"
                     /locus_tag="COSY_0787"
                     /note="The HCP family of iron-sulfur proteins includes
                     hybrid cluster protein (HCP), acetyl-CoA synthase (ACS),
                     and carbon monoxide dehydrogenase (CODH), all of which
                     contain [Fe4-S4] metal clusters at their active sites.
                     These proteins have a conserved...; Region: HCP_like;
                     cl14655"
                     /db_xref="CDD:246686"
     gene            complement(823327..824892)
                     /gene="dsrK"
                     /locus_tag="COSY_0788"
                     /db_xref="GeneID:5172342"
     CDS             complement(823327..824892)
                     /gene="dsrK"
                     /locus_tag="COSY_0788"
                     /note="Fe-S oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrK"
                     /protein_id="YP_001219618.1"
                     /db_xref="GI:148244924"
                     /db_xref="GeneID:5172342"
                     /translation="MVKEFDIPILPTYLETPKLKEGVMDGEGPFKSAQEFQNPLGFPG
                     EKVDNWQKVAIDKIGELKSKYRSVQVFLDSCVKCGACTDKCHYFLGSSDPKNMPVARQ
                     DLFRSVYRRHFTFAGKYFPKLVGAKELDDDMLDDWYNYFHQCSQCRRCSVFCPYGIDT
                     AEISMAAREVLDVVGIGQKYCNQILGKALTIGNNLGLPEPALRDTLLDLEEEIEEETG
                     GIAVKYPLDQKGAEILLITPSADFFAEPHIDGLIGYGKVFHQDGVSWTLSSYASEGAN
                     FGMFIGSYDVMRKAALRIRKAALDLEVSRVMVGECGHAWRVAYSFWNTLSGVGVGAAD
                     EFSQKLQDQLDHRYPQPQHIIEYTHDLIQRGKLVFDKSANDDRTVTFHDSCNVARATN
                     MGGILGGQFILPREVIKAVCNNYVDMERSTIKESTFCCGGGGGLLTDDLMEIRVKGAV
                     PRMQALKTVEKDNGVNTLAAICAICKSQFSKVLPKFDFDPYMIVSVHQLVSEAIIMDR
                     RKIEVQEDKSEVD"
     misc_feature    complement(824416..824670)
                     /gene="dsrK"
                     /locus_tag="COSY_0788"
                     /note="4Fe-4S dicluster domain; Region: Fer4_17;
                     pfam13534"
                     /db_xref="CDD:222205"
     misc_feature    complement(823381..>823863)
                     /gene="dsrK"
                     /locus_tag="COSY_0788"
                     /note="Fe-S oxidoreductase [Energy production and
                     conversion]; Region: GlpC; COG0247"
                     /db_xref="CDD:223325"
     gene            complement(824894..825667)
                     /gene="dsrM"
                     /locus_tag="COSY_0789"
                     /db_xref="GeneID:5172339"
     CDS             complement(824894..825667)
                     /gene="dsrM"
                     /locus_tag="COSY_0789"
                     /note="Similar to nitrate reductase gamma subunit."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrM"
                     /protein_id="YP_001219619.1"
                     /db_xref="GI:148244925"
                     /db_xref="GeneID:5172339"
                     /translation="MSIISIFFTALFYISLIVFLVGMVKKIYQFGITPAPLKIPIAPT
                     PLTQKGVVMRIIREIVLFESLFRSNKWIWLFGWLFHIGLLLISIRHIRYFWPDDLPDI
                     FLLTQSFKYAAFVMVFGLIGLILRRIFVERIRYISAPSDYLMLIMLLIIGISGMIMTF
                     TSNHTDIIMVKEFTSGLVSFNWKNLPTEVYFLIHIFLVFVLMVIFPISKLLHIPGIFF
                     SPTLNQVDDARSKRHIAPWALKQEQEHATQLEQILGKDE"
     misc_feature    complement(825029..825478)
                     /gene="dsrM"
                     /locus_tag="COSY_0789"
                     /note="Nitrate reductase gamma subunit; Region:
                     Nitrate_red_gam; cl00959"
                     /db_xref="CDD:242222"
     gene            complement(825744..826067)
                     /gene="dsrC"
                     /locus_tag="COSY_0790"
                     /db_xref="GeneID:5172365"
     CDS             complement(825744..826067)
                     /gene="dsrC"
                     /locus_tag="COSY_0790"
                     /note="dissimilatory sulfite reductase (desulfoviridin)
                     gamma subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrC"
                     /protein_id="YP_001219620.1"
                     /db_xref="GI:148244926"
                     /db_xref="GeneID:5172365"
                     /translation="MADILGAKVDEEGFLVDLGDWSKEIAEQMAKDDDVSLSEEHWDV
                     INFLREYFEEYQIAPAVRVLTKAIAKRMGKDKGNSKYLYSLFPYGPGKQGCRFAGLPK
                     PTGCI"
     misc_feature    complement(825747..826043)
                     /gene="dsrC"
                     /locus_tag="COSY_0790"
                     /note="DsrC like protein; Region: DsrC; pfam04358"
                     /db_xref="CDD:146805"
     misc_feature    complement(825747..826040)
                     /gene="dsrC"
                     /locus_tag="COSY_0790"
                     /note="Dissimilatory sulfite reductase (desulfoviridin),
                     gamma subunit [Inorganic ion transport and metabolism];
                     Region: DsrC; COG2920"
                     /db_xref="CDD:225472"
     gene            complement(826094..826390)
                     /gene="dsrH"
                     /locus_tag="COSY_0791"
                     /db_xref="GeneID:5172316"
     CDS             complement(826094..826390)
                     /gene="dsrH"
                     /locus_tag="COSY_0791"
                     /note="gamma subunit of DsrEFH"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrH"
                     /protein_id="YP_001219621.1"
                     /db_xref="GI:148244927"
                     /db_xref="GeneID:5172316"
                     /translation="MLHTVNKSSFERNSLKSCINTIDDTSVILLIEDGVISATKNINS
                     SMIANLANQGRVYALQGDVEARGVSSKLVDNIKLVNYTGFVDLVVEHGTSVSWV"
     misc_feature    complement(826106..826372)
                     /gene="dsrH"
                     /locus_tag="COSY_0791"
                     /note="DsrH like protein; Region: DsrH; pfam04077"
                     /db_xref="CDD:217876"
     gene            complement(826402..826806)
                     /gene="dsrF"
                     /locus_tag="COSY_0792"
                     /db_xref="GeneID:5172330"
     CDS             complement(826402..826806)
                     /gene="dsrF"
                     /locus_tag="COSY_0792"
                     /note="beta subunit of DsrEFH"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrF"
                     /protein_id="YP_001219622.1"
                     /db_xref="GI:148244928"
                     /db_xref="GeneID:5172330"
                     /translation="MSIKKFMYLNRRSSFGTVYAIESLEVVLVAAAFDQDVSLAFIDD
                     GVYQIIKGQNTNGIGMKNFSKTFHALGDYEINKLYVSAESLEERGLSADDLMPLVYED
                     EDDNWEEKSSVKVVSNLEISKIMSKQDVCFSF"
     misc_feature    complement(826405..826794)
                     /gene="dsrF"
                     /locus_tag="COSY_0792"
                     /note="DsrE/DsrF-like family; Region: DrsE; cl00672"
                     /db_xref="CDD:242020"
     gene            complement(826810..827211)
                     /gene="dsrE"
                     /locus_tag="COSY_0793"
                     /db_xref="GeneID:5172324"
     CDS             complement(826810..827211)
                     /gene="dsrE"
                     /locus_tag="COSY_0793"
                     /note="alpha subunit of DsrEFH"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrE"
                     /protein_id="YP_001219623.1"
                     /db_xref="GI:148244929"
                     /db_xref="GeneID:5172324"
                     /translation="MKISIQINEGPYQHQASDTAYQFAKAAIEKGHEIFRVFFYHDGV
                     NNASRFTIPPQDDRNIVNQWAELGIKNANGEPELVVCVAAALRRGMLDESEASKNGID
                     GNNIHPAFRISGLGQLIEAGIQSDRLVVFGD"
     misc_feature    complement(826819..827208)
                     /gene="dsrE"
                     /locus_tag="COSY_0793"
                     /note="sulfur relay protein TusD/DsrE; Region:
                     sulf_tusD_dsrE; TIGR03012"
                     /db_xref="CDD:234086"
     gene            complement(827224..828297)
                     /gene="dsrB"
                     /locus_tag="COSY_0794"
                     /db_xref="GeneID:5172320"
     CDS             complement(827224..828297)
                     /gene="dsrB"
                     /locus_tag="COSY_0794"
                     /note="dissimilatory sulfite reductase (desulfoviridin)
                     beta subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrB"
                     /protein_id="YP_001219624.1"
                     /db_xref="GI:148244930"
                     /db_xref="GeneID:5172320"
                     /translation="MAEAPRMPIESGCPDPIQYMHPTMRRNYGQWVYHDRPRPGVLHH
                     TSKNHEEIWTVRCGTSRQMDVYTIRKLADIADEFADGHVRFTMRSNVEYMVADEAKVE
                     SLIAALTESGFPVGGTGPSVTMISHTQGWLHCDIPGTDASGIVKSLMDEMHEEFTREE
                     MPNRVHMTTSCCQINCGGQGDIALNVQHTKPPKINHDLVANVCERPTVVARCPVAAIR
                     PAMVNGKPTLEVDEKKCICCGACFPPCPPMQINDPEYSKIALWIGGKNSNARSKPSFH
                     KLVASNLPNNPPRWPEVTAVVKNILSVYKEDARDWERMGEWVDRIGWPAFFEKTGLPF
                     TKFHINDWKGARHELNSSAHIRF"
     misc_feature    complement(827227..828228)
                     /gene="dsrB"
                     /locus_tag="COSY_0794"
                     /note="sulfite reductase, dissimilatory-type beta subunit;
                     Region: dsrB; TIGR02066"
                     /db_xref="CDD:131121"
     misc_feature    complement(827968..828141)
                     /gene="dsrB"
                     /locus_tag="COSY_0794"
                     /note="Nitrite/Sulfite reductase ferredoxin-like half
                     domain; Region: NIR_SIR_ferr; pfam03460"
                     /db_xref="CDD:217572"
     gene            complement(828373..829674)
                     /gene="dsrA"
                     /locus_tag="COSY_0795"
                     /db_xref="GeneID:5172315"
     CDS             complement(828373..829674)
                     /gene="dsrA"
                     /locus_tag="COSY_0795"
                     /note="dissimilatory sulfite reductase (desulfoviridin)
                     alpha subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrA"
                     /protein_id="YP_001219625.1"
                     /db_xref="GI:148244931"
                     /db_xref="GeneID:5172315"
                     /translation="MAELYNTPNLDELENGPWPSFVTGLKRLASDSHAGAEMARDVLG
                     TLETSYVTKKGYWKGGTVGVIGYGGGIIPRFNELKDDKGEYKFPAAGEFHTLRVQPPA
                     GMHYTSTLLRDMCDMFVDNGGSGLIALHGQSGDIMLQGSTEETTQTIFNTFNDYGFDL
                     GGAGPAVRTGMSCVGASRCEMSNVNEQAVLRTLVNAFLDDMHRPALPYKMKFKVSGCS
                     NDCMNTVQRADFAVIGTWRDDIKVNQYLWQSMVADKGRSYVVDNIISRCPTSAMTLNE
                     DDSVTIDNKNCVKCMHCLNVTSPLTHKYIAKGDIEPILATGDDKGVMIIMGGKRTLKI
                     GDLFGSVVVPFMKMETADNLEEIENLAGEVIDFFAENALEHERTGEMIERIGVVNFLE
                     GIGLNVDPNMVNSTRTSSYVRMDTWDEEAIKWFENKAEASA"
     misc_feature    complement(828385..829647)
                     /gene="dsrA"
                     /locus_tag="COSY_0795"
                     /note="sulfite reductase, dissimilatory-type alpha
                     subunit; Region: dsrA; TIGR02064"
                     /db_xref="CDD:233704"
     gene            complement(829907..831340)
                     /gene="gltD"
                     /locus_tag="COSY_0796"
                     /db_xref="GeneID:5172307"
     CDS             complement(829907..831340)
                     /gene="gltD"
                     /locus_tag="COSY_0796"
                     /EC_number="1.4.1.13"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase (NADPH) small chain"
                     /protein_id="YP_001219626.1"
                     /db_xref="GI:148244932"
                     /db_xref="GeneID:5172307"
                     /translation="MGKITGFKEFNRKTEAYRSVDLRIKDYGEIFTGYSDAVHLQEQA
                     ARCMDCGVPFCQSENGCPVDNLIPEFNDLIYHNKWQEALTRLLKTNNFPEFTGRVCPA
                     PCEGSCVLGINNSAVTIKNIEQAIIDRGFDEDRVKPYTVEYRTGKKIAIIGSGPAGLA
                     AADELNKIGHNVTIFERDDRIGGLLMYGIPNMKLSKDVVDRRVKLMQNSGIEFIINVN
                     VGKDITTIQLQQDFDALVLTTGVSKARDLLVDNRQAQGVHMAMEYLTHNTKSLLDNGY
                     AEESDLSAKDKDVIVIGGGDTGTDCISTALRQGARSIVNFELMSKPPTKRMSNNPWPL
                     WPLIYRVDYGHAEVTEVFGKDPRQYCLMTKSFIKDDQNSVIGLNTVNVDFQNGEFMEM
                     NGSERTWSAQLVLLSMGFVSPEHYLSDDANIKLDEHGNYKAKYGQYTTSQKGIFTAGD
                     CRRGQSLVVWAINEGRGVAVKVNEYLT"
     misc_feature    complement(829910..831340)
                     /gene="gltD"
                     /locus_tag="COSY_0796"
                     /note="glutamate synthase subunit beta; Reviewed; Region:
                     gltD; PRK12810"
                     /db_xref="CDD:237213"
     misc_feature    complement(<830792..830890)
                     /gene="gltD"
                     /locus_tag="COSY_0796"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; pfam13450"
                     /db_xref="CDD:205628"
     gene            831491..831844
                     /gene="rplS"
                     /locus_tag="COSY_0797"
                     /db_xref="GeneID:5172516"
     CDS             831491..831844
                     /gene="rplS"
                     /locus_tag="COSY_0797"
                     /note="this protein is located at the 30S-50S ribosomal
                     subunit interface and may play a role in the structure and
                     function of the aminoacyl-tRNA binding site"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="YP_001219627.1"
                     /db_xref="GI:148244933"
                     /db_xref="GeneID:5172516"
                     /translation="MNLIDQIENEQLRSDLPLFVSGDTIIVQVKVREGERERLQAFEG
                     VVIAKKNRGIGSAFTVRKISHGEGVERVFQTHSKMIDSIKVKRRGKVHQAKLYYLRGL
                     TGKKARIKEKLQIRK"
     misc_feature    831491..831829
                     /gene="rplS"
                     /locus_tag="COSY_0797"
                     /note="50S ribosomal protein L19; Provisional; Region:
                     rplS; PRK05338"
                     /db_xref="CDD:235418"
     gene            complement(831932..832411)
                     /gene="greA"
                     /locus_tag="COSY_0798"
                     /db_xref="GeneID:5172397"
     CDS             complement(831932..832411)
                     /gene="greA"
                     /locus_tag="COSY_0798"
                     /note="necessary for efficient RNA polymerase
                     transcription elongation past template-encoded arresting
                     sites; arresting sites in DNA have the property of
                     trapping a certain fraction of elongating RNA polymerases
                     that pass through, resulting in locked ternary complexes.
                     Cleavage of the nascent transcript by cleavage factors
                     such as GreA or GreB allows the resumption of elongation
                     from the new 3'terminus"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="YP_001219628.1"
                     /db_xref="GI:148244934"
                     /db_xref="GeneID:5172397"
                     /translation="MNNIPVTAFGAKALEAALLKLKDVSRPRIIEDIRIARAHGDLKE
                     NAEYHAAKEEQSFVEGRIKEIELKLSRMQIIDVTKLSQDGRCVFGTTITLMNSVDNSE
                     ITYQIVGEDEADISLDKISCHSPIASALMGNEEGDKVIVKAPKGDIVYKILSVEYYI"
     misc_feature    complement(831941..832411)
                     /gene="greA"
                     /locus_tag="COSY_0798"
                     /note="transcription elongation factor GreA; Reviewed;
                     Region: greA; PRK00226"
                     /db_xref="CDD:234693"
     misc_feature    complement(832190..832402)
                     /gene="greA"
                     /locus_tag="COSY_0798"
                     /note="Transcription elongation factor, N-terminal;
                     Region: GreA_GreB_N; pfam03449"
                     /db_xref="CDD:217565"
     misc_feature    complement(831941..832168)
                     /gene="greA"
                     /locus_tag="COSY_0798"
                     /note="Transcription elongation factor, GreA/GreB, C-term;
                     Region: GreA_GreB; pfam01272"
                     /db_xref="CDD:201702"
     gene            complement(832414..835620)
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /db_xref="GeneID:5171914"
     CDS             complement(832414..835620)
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /EC_number="6.3.5.5"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="YP_001219629.1"
                     /db_xref="GI:148244935"
                     /db_xref="GeneID:5171914"
                     /translation="MPKRQDLSSILIIGAGPIVIGQACEFDYSGAQACSALREEGYRV
                     ILVNSNPATIMTDPTMADSTYIEPIEWRIVEKIIEVEKPDALLPTMGGQTALNCALDL
                     ERHGVLDKHCVEMIGAKKEAINKAEDRDLFREAMLKIGLDMPKAAVAHNMEEAFTIQE
                     TVGFPTVIRPSFTMGGSGGGIAYNKDEFVKICECGLDLSPINELLVEESILGWKEFEL
                     EVIRDRKDNCIIICSIENFDPIGIHTGDSITVAPAQTLTDKEYQAMRDASLAVLREIG
                     VDTGGSNVQFALNPENGRLTIIEMNPRVSRSSALASKATGFPIAKVAAKLAIGYTLDE
                     LNNDITNGKTPASFEPSIDYVVTKIPRFAFEKFPGANDRLTTQMKSVGEVMAIGSTFQ
                     ESLQKALRGLETDKVGLDPIVDLNADDARNKIRSECISARSDRIFYLADAFRLGMSLK
                     EVFDLSKVDSWFLAQIQDIIATELQINSTNVTDIDADKMFSLKRKGFSDARLAQLFCC
                     NESSVRERRHALNVKSVFKRVDSCAAEFDTQTAYLYSTYQLECEANPTDKKKIMILGG
                     GPNRIGQGIEFDYCCVHASLALREDGFETIMVNCNPETVSTDYDISDRLYFEPLTLED
                     VLAIIDIENPDGIIVHYGGQTPLKLAKALEKSGANIIGTTPDAIDLAEDRERFSKMLQ
                     DLKLKQPLNGTARSLEQAQDIANAIGFPLVVRPSYVLGGRAMKIVYDKDSLEHYMYTA
                     VKVSNDSPILLDSFLDHAIEVDIDAICDGENVVIGGIMQHIEQAGIHSGDSACSLPPY
                     SLTNKVLDEMRAQVILMAKKLNVVGLMNTQLAYQNGEIYIIEVNPRASRTVPFVSKAI
                     GVPLANIAARVMSGVSLKAQNFTKEIIPEHFSVKEAVFPFNKFLGVDPILGPEMRSTG
                     EVMGVGKDFASAFDKAQLAAGSRVPENGKVFVSLRKLDRNELINLGNKLLIQGFSLVS
                     TRSNRDMLNAAGLKCEVINKVSEGSPHIIDMIKNDGVDLIINSTEDTQGVEDAAEIRC
                     QALTHKIPFTTTVEAAFAMLDGLKVIDKFTITKLQSLY"
     misc_feature    complement(832417..835620)
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="carbamoyl phosphate synthase large subunit;
                     Reviewed; Region: carB; PRK05294"
                     /db_xref="CDD:235393"
     misc_feature    complement(835255..835596)
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="Carbamoyl-phosphate synthase L chain, N-terminal
                     domain; Region: CPSase_L_chain; pfam00289"
                     /db_xref="CDD:201133"
     misc_feature    complement(834616..835239)
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="Carbamoyl-phosphate synthase L chain, ATP binding
                     domain; Region: CPSase_L_D2; pfam02786"
                     /db_xref="CDD:190425"
     misc_feature    complement(833980..834351)
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="Carbamoyl-phosphate synthetase large chain,
                     oligomerisation domain; Region: CPSase_L_D3; pfam02787"
                     /db_xref="CDD:217231"
     misc_feature    complement(833620..833946)
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="Carbamoyl-phosphate synthase L chain, N-terminal
                     domain; Region: CPSase_L_chain; pfam00289"
                     /db_xref="CDD:201133"
     misc_feature    complement(833002..833604)
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="ATP-grasp domain; Region: ATP-grasp_4; cl17255"
                     /db_xref="CDD:247809"
     misc_feature    complement(832471..832797)
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="Methylglyoxal synthase-like domain from type II
                     glutamine-dependent carbamoyl phosphate synthetase (CSP).
                     CSP, a CarA and CarB heterodimer, catalyzes the production
                     of carbamoyl phosphate which is subsequently employed in
                     the metabolic pathways...; Region: MGS_CPS_II; cd01424"
                     /db_xref="CDD:238712"
     misc_feature    complement(order(832573..832581,832645..832647,
                     832693..832698,832702..832704,832762..832764,
                     832780..832782))
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="IMP binding site; other site"
                     /db_xref="CDD:238712"
     misc_feature    complement(order(832612..832614,832648..832650,
                     832654..832659,832663..832665,832687..832689,
                     832699..832701))
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238712"
     misc_feature    complement(order(832477..832479,832489..832491,
                     832504..832506))
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="interdomain contacts; other site"
                     /db_xref="CDD:238712"
     misc_feature    complement(832498..832506)
                     /gene="carB"
                     /locus_tag="COSY_0799"
                     /note="partial ornithine binding site; other site"
                     /db_xref="CDD:238712"
     gene            complement(835643..836329)
                     /gene="vacJ"
                     /locus_tag="COSY_0800"
                     /db_xref="GeneID:5172503"
     CDS             complement(835643..836329)
                     /gene="vacJ"
                     /locus_tag="COSY_0800"
                     /codon_start=1
                     /transl_table=11
                     /product="surface lipoprotein VacJ"
                     /protein_id="YP_001219630.1"
                     /db_xref="GI:148244936"
                     /db_xref="GeneID:5172503"
                     /translation="MKNLFMSFLLLIFSSIVMAENIDPFEGLNRTIFEFNQTLDENIF
                     YPVAKVYKEFLPKTMQNRVSDFFSNLDDVSTLGNELLQFKLLDSVNTFGRILVNSTIG
                     LAGLFDVASNIWIEKTDEDFGQTMAVWGVPSGPYIVLPILGPSSIRDSVGTYINVTEN
                     VNVNKWLNATEETTLLLTRAVDTRVKLSPIIDLLKNSDDFYIATRSSFLQKRQFDIFD
                     GNPPIEYDDF"
     misc_feature    complement(835649..836263)
                     /gene="vacJ"
                     /locus_tag="COSY_0800"
                     /note="VacJ like lipoprotein; Region: VacJ; cl01073"
                     /db_xref="CDD:242285"
     gene            complement(836326..837447)
                     /gene="carA"
                     /locus_tag="COSY_0801"
                     /db_xref="GeneID:5171822"
     CDS             complement(836326..837447)
                     /gene="carA"
                     /locus_tag="COSY_0801"
                     /EC_number="6.3.5.5"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase small subunit"
                     /protein_id="YP_001219631.1"
                     /db_xref="GI:148244937"
                     /db_xref="GeneID:5171822"
                     /translation="MLQVALLALEDGKIFYGKSIGVNGITLGEVVFNTSMTGYQEILT
                     DPSYVQQIVILTCPHIGNTGINLVDEESDKIHVSGLIIRDLSLIASNWRSDISLGAYL
                     KHNNIVAISDIDTRALTRHLRKQGSLKGCIITGNDIDPEVAIAKAKLFVGMKNIDLAK
                     VVSTTQSYEFNQGSYSLVNTKFNELNTKFKVVVYDFGVKKNILKMLVDKGCALTVVNA
                     QTSATKVLERNPDGVFLSNGPGDPEPCDYAIKNIQILLGKDIPLFGICLGHQLLSLAV
                     GATTQKMKFGHHGANHPVQNLHTKQVIITSQNHGFVVSDENMPNDLEVTHRSLFDNSI
                     QGIHIVNKKAFGFQGHPEASPGPHDMSSFFDTFIREMNE"
     misc_feature    complement(836335..837435)
                     /gene="carA"
                     /locus_tag="COSY_0801"
                     /note="carbamoyl phosphate synthase small subunit;
                     Reviewed; Region: PRK12564"
                     /db_xref="CDD:237139"
     misc_feature    complement(837052..837435)
                     /gene="carA"
                     /locus_tag="COSY_0801"
                     /note="Carbamoyl-phosphate synthase small chain, CPSase
                     domain; Region: CPSase_sm_chain; smart01097"
                     /db_xref="CDD:198165"
     misc_feature    complement(836344..836877)
                     /gene="carA"
                     /locus_tag="COSY_0801"
                     /note="Small chain of the glutamine-dependent form of
                     carbamoyl phosphate synthase, CPSase II; Region:
                     GATase1_CPSase; cd01744"
                     /db_xref="CDD:153215"
     misc_feature    complement(order(836392..836394,836398..836400,
                     836650..836652))
                     /gene="carA"
                     /locus_tag="COSY_0801"
                     /note="catalytic site [active]"
                     /db_xref="CDD:153215"
     misc_feature    complement(order(836371..836376,836380..836385,
                     836461..836463,836542..836544,836548..836550,
                     836569..836571,836575..836577))
                     /gene="carA"
                     /locus_tag="COSY_0801"
                     /note="subunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:153215"
     gene            837558..837827
                     /locus_tag="COSY_0802"
                     /db_xref="GeneID:5172509"
     CDS             837558..837827
                     /locus_tag="COSY_0802"
                     /note="heavy-metal-associated domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219632.1"
                     /db_xref="GI:148244938"
                     /db_xref="GeneID:5172509"
                     /translation="MKIIVDNIKCVGCINIITKKLIATFNTKKVNINIEQGIVKIDVD
                     STKKSEVAQVLLNLGYPEINSIHGFNSTKAKAKSFVSCTIGRINI"
     misc_feature    837564..837740
                     /locus_tag="COSY_0802"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cl00207"
                     /db_xref="CDD:241686"
     gene            837824..838024
                     /gene="thiS"
                     /locus_tag="COSY_0803"
                     /db_xref="GeneID:5172335"
     CDS             837824..838024
                     /gene="thiS"
                     /locus_tag="COSY_0803"
                     /note="sulphur carrier protein"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiS"
                     /protein_id="YP_001219633.1"
                     /db_xref="GI:148244939"
                     /db_xref="GeneID:5172335"
                     /translation="MTFTLNGKLLKMADNLNAYDLIIQLGYENQRIALEINETIIPKS
                     KHATFALNEGDIIEIIKAVGGG"
     misc_feature    837827..838021
                     /gene="thiS"
                     /locus_tag="COSY_0803"
                     /note="ThiaminS ubiquitin-like sulfur carrier protein;
                     Region: ThiS; cd00565"
                     /db_xref="CDD:176353"
     misc_feature    order(837941..837943,837995..838003)
                     /gene="thiS"
                     /locus_tag="COSY_0803"
                     /note="thiS-thiF/thiG interaction site; other site"
                     /db_xref="CDD:176353"
     gene            complement(838542..839588)
                     /locus_tag="COSY_0804"
                     /db_xref="GeneID:5172679"
     CDS             complement(838542..839588)
                     /locus_tag="COSY_0804"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219634.1"
                     /db_xref="GI:148244940"
                     /db_xref="GeneID:5172679"
                     /translation="MTNKQIKAVSLISGGLDSLLSTKIILDQGIHVEGINFFTGFCME
                     GHTNTIRKQKKNGLKRNNALWVAEKLGIKLHIIDVIEEYRDVLLNPKHGYGKNMNPCL
                     DCKGFMVKKAKEWMVEYEFDFIITGEVVGQRPMSQRKETMPIIQLESGANDLLLRPLC
                     AKHLPVTKAEIENWVDREKLLDFSGRTRKPQMFLAKEYGFDGYATPAGGCCFLTDKQY
                     SDKLVDMWKSRGNRNYQLDDLMMLKVGRHIRPNPRFKMIIAREEGEVKFLEGYRNQYA
                     NLYPTSCNGPLALIDGDPNQADLQIAAKILARYSQGRGYDSVDIEIKLDVDTMQTLNI
                     KPFSADEIQKDWMV"
     misc_feature    complement(838614..839582)
                     /locus_tag="COSY_0804"
                     /note="Predicted tRNA(5-methylaminomethyl-2-thiouridylate)
                     methyltransferase, contains the PP-loop ATPase domain
                     [Translation, ribosomal structure and biogenesis]; Region:
                     TrmU; COG0482"
                     /db_xref="CDD:223558"
     misc_feature    complement(838992..839570)
                     /locus_tag="COSY_0804"
                     /note="ThiI is required for thiazole synthesis in the
                     thiamine biosynthesis pathway. It belongs to the Adenosine
                     Nucleotide Hydrolysis suoerfamily and predicted to bind to
                     Adenosine nucleotide; Region: ThiI; cd01712"
                     /db_xref="CDD:238845"
     misc_feature    complement(order(839472..839474,839478..839480,
                     839535..839546,839550..839558))
                     /locus_tag="COSY_0804"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238845"
     gene            839956..840246
                     /locus_tag="COSY_0805"
                     /db_xref="GeneID:5172328"
     CDS             839956..840246
                     /locus_tag="COSY_0805"
                     /note="dissimilatory sulfite reductase (desulfoviridin)
                     gamma subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular sulfur oxidation protein DsrC"
                     /protein_id="YP_001219635.1"
                     /db_xref="GI:148244941"
                     /db_xref="GeneID:5172328"
                     /translation="MELKRTGNGYLVDPTIWTEDIMHKMAKEDEIELTRSMVNQILTA
                     RKYFEENSSVPPIRTFAKVVGIDKKILFKEWLTGPMKPITKYGGMPQPTGCV"
     misc_feature    839977..840243
                     /locus_tag="COSY_0805"
                     /note="DsrC like protein; Region: DsrC; cl01101"
                     /db_xref="CDD:214107"
     gene            complement(840275..842872)
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /db_xref="GeneID:5172322"
     CDS             complement(840275..842872)
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /EC_number="6.1.1.7"
                     /note="Catalyzes a two-step reaction, first charging an
                     alanyl molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA synthetase"
                     /protein_id="YP_001219636.1"
                     /db_xref="GI:148244942"
                     /db_xref="GeneID:5172322"
                     /translation="MKTAQIRQKFLDYFESKGHIIESSASLIPHNDKTLLFVNAGMVP
                     FKDVFSGIEKRPYTRAVSVQRCARAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFK
                     REAIHYAWEFLTKELNLPKKNLWVSVFDQDNEAEDIWVNEIGFPKNRISRCGAKDNFW
                     QMGDTGPCGPSSEIFYDHGEHIAGGPPGHANEDGDRYIEIWNLVFTEFDKQEDGYLKP
                     LAVPCVDTGMGLERLVAVLQHKNNNYDTDGFQNLVKAVVNLTPKFNNIKDNNASVRVI
                     TDHIRSAAFMIVDGVIPSNEGRGYVLRRIIRRGIRHGHKMGIGKVFFYRLASILALEF
                     KDVYPELEQALSKVEKVLKREEQRFSKTLDQGMSILEEVITNFKGSEINGKIVFKLYD
                     TYGFPVDLTSDIARERNLTIDMSGFEVEMTKQRDRARQASDFKISEKGVDIAERTEFL
                     GYKQLKNVSLIQAIINNNELVEKIEVGDHGIVVLAQSSFYAESGGQIGDKGILSNMQV
                     EFRVDHTNKQKSGAFEHHGVLNKGVLKVSDAVQANVDKKSRKCIARNHSATHLLHAAL
                     HIVLGKAVMQKGSLVGSEKLRFDFSYDKVIVKSDLERIESIVNRKILGNTKVYTDITN
                     IEGAKKKGAMTLFGKKYGDTVRVLTMGKNEFSVELCGGTHVNQLGDIGLFRIISESSV
                     SAGVRRIEALTGYDAYQFDNRIQNSLNKIAQMTRSSNTEVVGKVTQLIKQQKELEKQI
                     ATFQKKIANNQGDDLIVQAQEVKGIKLLSTVVEGVTSKDLRNIVDKLKDKLSSAVIVL
                     AVVINDKVSLVTGVTKDLTKQYQARKILNHVAKQIGGKGDGRSDMAQGGGTKPECLIK
                     ALASVKSLI"
     misc_feature    complement(840278..842872)
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /note="alanyl-tRNA synthetase; Reviewed; Region: alaS;
                     PRK00252"
                     /db_xref="CDD:234701"
     misc_feature    complement(842153..842866)
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /note="Alanyl-tRNA synthetase (AlaRS) class II core
                     catalytic domain. AlaRS is a homodimer. It is responsible
                     for the attachment of alanine to the 3&apos; OH group of
                     ribose of the appropriate tRNA. This domain is primarily
                     responsible for ATP-dependent...; Region: AlaRS_core;
                     cd00673"
                     /db_xref="CDD:238360"
     misc_feature    complement(842798..842812)
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /note="motif 1; other site"
                     /db_xref="CDD:238360"
     misc_feature    complement(order(842177..842179,842186..842191,
                     842201..842206,842261..842263,842273..842278,
                     842588..842596,842600..842602,842606..842608,
                     842669..842671,842723..842725,842729..842731))
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /note="active site"
                     /db_xref="CDD:238360"
     misc_feature    complement(842666..842674)
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /note="motif 2; other site"
                     /db_xref="CDD:238360"
     misc_feature    complement(842177..842194)
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /note="motif 3; other site"
                     /db_xref="CDD:238360"
     misc_feature    complement(840806..840940)
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /note="Threonyl and Alanyl tRNA synthetase second
                     additional domain; Region: tRNA_SAD; smart00863"
                     /db_xref="CDD:197931"
     misc_feature    complement(<840758..840847)
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /note="hypothetical protein; Region: PHA01516"
                     /db_xref="CDD:107038"
     misc_feature    complement(840284..840496)
                     /gene="alaS"
                     /locus_tag="COSY_0806"
                     /note="DHHA1 domain; Region: DHHA1; pfam02272"
                     /db_xref="CDD:216955"
     gene            complement(842921..843535)
                     /locus_tag="COSY_0807"
                     /db_xref="GeneID:5172018"
     CDS             complement(842921..843535)
                     /locus_tag="COSY_0807"
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5 family translation factor"
                     /protein_id="YP_001219637.1"
                     /db_xref="GI:148244943"
                     /db_xref="GeneID:5172018"
                     /translation="MVKLLEIHPKNPQIRLLEQVADELRRGAVIVYPTDSGYALGATL
                     GNKNGLERIRCIRNLSKQHYFTLMMRDLAHIGEYAKLDNISFRLLKRILPGSYTFVLQ
                     GTRDVPNRLLHAKKKTIGFRVSNHGLVQALLDVLNEPIINTSLIIKDCEFFDIDDVYD
                     SLEKRVDVIIDGGYCPLEPTTVIDLSLSSINIIRQGAGDISLII"
     misc_feature    complement(842933..843535)
                     /locus_tag="COSY_0807"
                     /note="Telomere recombination; Region: Sua5_yciO_yrdC;
                     cl00305"
                     /db_xref="CDD:241768"
     gene            complement(843529..844359)
                     /locus_tag="COSY_0808"
                     /db_xref="GeneID:5172314"
     CDS             complement(843529..844359)
                     /locus_tag="COSY_0808"
                     /note="PHP (Polymerase and Histidinol Phosphatase) domain
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219638.1"
                     /db_xref="GI:148244944"
                     /db_xref="GeneID:5172314"
                     /translation="MVIDLHNHSYYSDGILSPTEVVRLANKQNCDMVALTDHDTIDGL
                     AEASYEANKLNLQFVFGTEISATWNNMTIHILGLKINPNNKILQTGLKKHQQLREVRS
                     EKIACSLEGAGIIGAMEKTKAITKTGIITRTHFAQMLIQEGICKNMKSVFRNFLTGNN
                     PGSVSVKWAQFDEVIGWIRSAGGVAVLAHPLRYRVTHTQIKRMMSDLAVNGCTGIEVV
                     TAMSSLDEIILVSQWSGELGLLASSGSDYHGWSNQRVQIGCLQDLPNYEQAIWKNWIW
                     "
     misc_feature    complement(843616..844359)
                     /locus_tag="COSY_0808"
                     /note="Predicted metal-dependent phosphoesterases (PHP
                     family) [General function prediction only]; Region:
                     COG0613"
                     /db_xref="CDD:223686"
     misc_feature    complement(<844129..844353)
                     /locus_tag="COSY_0808"
                     /note="Polymerase and Histidinol Phosphatase domain of
                     Histidinol phosphate phosphatase (HisPPase) AMP bound;
                     Region: PHP_HisPPase_AMP; cd07438"
                     /db_xref="CDD:213993"
     misc_feature    complement(order(844138..844140,844171..844173,
                     844246..844248,844321..844323,844336..844338,
                     844342..844344))
                     /locus_tag="COSY_0808"
                     /note="active site"
                     /db_xref="CDD:213993"
     misc_feature    complement(843613..>843855)
                     /locus_tag="COSY_0808"
                     /note="Polymerase and Histidinol Phosphatase domain of
                     Histidinol phosphate phosphatase (HisPPase) AMP bound;
                     Region: PHP_HisPPase_AMP; cd07438"
                     /db_xref="CDD:213993"
     gene            844437..846284
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /db_xref="GeneID:5172306"
     CDS             844437..846284
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /EC_number="2.6.1.16"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine--fructose-6-phosphate
                     aminotransferase (isomerizing)"
                     /protein_id="YP_001219639.1"
                     /db_xref="GI:148244945"
                     /db_xref="GeneID:5172306"
                     /translation="MCGIVGGICKYNITPILLNGLKRLEYRGYDSAGIVVLSNNNKLN
                     RVRAVGKVINLETNIQKQNSKIQGNVGIAHTRWATHGEPSTQNAHPHICFDTVSVVHN
                     GIIENFLKLKQEQKAQGYAFTSDTDTEVIVHGIHQALKTSKNLLQATQKSIKTFEGAY
                     GLGVISPSYPGHIVVARSGSPLIIGISNEGNFITSDQVALLGITKKFIFLEEGDIADI
                     TLNSITIYNQDDEQVNRVIKISNLNSKQIDLGDYKHYMQKEIFEQPQAIRDTLESRIT
                     KDTVSLSAFGHNAETIFTNIKHIQIIACGTSYNAGLVAKYWLEDIAKVPTNIEVASEY
                     RYRNPVVLNNTLLVTISQSGETTDTLEALKSVKQHHNNIHTLTICNCAESFLTRESEL
                     TLLTHAGPEISVASTKAFTTQLVSLALLSVAIGKCHKQVDKKQETAIVDGLNRLPGLI
                     KKTLEQESQIIELAQSFKNKFNAIFLGRGTMHAIAMEGALKLKEISYIHSEAFPAGEL
                     KHGPIALIDQDTPVIAIAPNDQLLDKLKSNLQEVKSRGSQMIVFEDEMSNVTPMQNMT
                     VMSITHNLGIITAPIIFTIPLQLLSYHVALIKGTNVDKPRNLAKSVTVE"
     misc_feature    844437..846281
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /note="glucosamine--fructose-6-phosphate aminotransferase;
                     Reviewed; Region: PRK00331"
                     /db_xref="CDD:234729"
     misc_feature    844440..845090
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /note="Glutamine amidotransferases class-II
                     (Gn-AT)_GFAT-type. This domain is found at the N-terminus
                     of glucosamine-6P synthase (GlmS, or GFAT in humans).  The
                     glutaminase domain catalyzes amide nitrogen transfer from
                     glutamine to the appropriate substrate. In...; Region:
                     GFAT; cd00714"
                     /db_xref="CDD:238366"
     misc_feature    order(844440..844442,844515..844517,844662..844667,
                     844671..844676,844701..844703,844740..844745,
                     844815..844820)
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /note="glutaminase active site [active]"
                     /db_xref="CDD:238366"
     misc_feature    845328..845711
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /note="SIS (Sugar ISomerase) domain repeat 1 found in
                     Glucosamine 6-phosphate synthase (GlmS) and
                     Glucosamine-6-phosphate deaminase (GlmD). The SIS domain
                     is found in many phosphosugar isomerases and phosphosugar
                     binding proteins. GlmS contains a N-terminal...; Region:
                     SIS_GlmS_GlmD_1; cd05008"
                     /db_xref="CDD:240141"
     misc_feature    order(845346..845351,845379..845384,845391..845396,
                     845415..845417,845421..845423,845433..845435,
                     845442..845444,845508..845510)
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:240141"
     misc_feature    order(845352..845357,845487..845495)
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /note="active site"
                     /db_xref="CDD:240141"
     misc_feature    845811..846275
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /note="SIS (Sugar ISomerase) domain repeat 2 found in
                     Glucosamine 6-phosphate synthase (GlmS) and
                     Glucosamine-6-phosphate deaminase (GlmD). The SIS domain
                     is found in many phosphosugar isomerases and phosphosugar
                     binding proteins. GlmS contains a N-terminal...; Region:
                     SIS_GlmS_GlmD_2; cd05009"
                     /db_xref="CDD:240142"
     misc_feature    order(845871..845873,845913..845915,845925..845927,
                     845931..845933,845937..845939,845943..845945,
                     845955..845957,845961..845969,845973..845984,
                     846033..846038,846048..846050,846054..846059,
                     846252..846257,846270..846272)
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:240142"
     misc_feature    order(845907..845909,845916..845918)
                     /gene="glmS"
                     /locus_tag="COSY_0809"
                     /note="active site"
                     /db_xref="CDD:240142"
     gene            846290..847528
                     /gene="pgi"
                     /locus_tag="COSY_0810"
                     /db_xref="GeneID:5172030"
     CDS             846290..847528
                     /gene="pgi"
                     /locus_tag="COSY_0810"
                     /EC_number="5.3.1.9"
                     /note="catalyzes the formation of D-fructose 6-phosphate
                     from D-glucose 6-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="YP_001219640.1"
                     /db_xref="GI:148244946"
                     /db_xref="GeneID:5172030"
                     /translation="MINILGFDSDFDPSLLDRIVNEKKKIGYYNLPNQDTTYINHYLK
                     QLNKRQNLNSISDVVVIGIGGSSLGAKAVYHFIRSIRQLKRNLHFMDSTDPITIANIC
                     NSLNISSTHFIVISKSGSTIETIAIYKHILAITKTIQLSHFPFTFITGKSSLLAQHAR
                     KVNGLIINIQQNIGGRFSLLSSAGIIPLALTGTKIDCLLKGAAKIKDSFFNQGYMQNL
                     LLKKATFYANNASNYNINALFSYTDSLKYFNDWYAQLWGESLGKKQKNSVFHVGLTPI
                     GLTGPKDQHSFLQLLYEGIRDKSVTFIKLKTFENHQKIPNITLEKLETFNLINQVKFS
                     TLINMQADAIIESLKKHTRIPLDEITLQKQDEFSIGQLIYYYELLTSLVGNLLNINTY
                     NQPGVEFGKNILIKKLQQQL"
     misc_feature    846290..847522
                     /gene="pgi"
                     /locus_tag="COSY_0810"
                     /note="glucose-6-phosphate isomerase; Provisional; Region:
                     PRK03868"
                     /db_xref="CDD:235168"
     misc_feature    <846491..846859
                     /gene="pgi"
                     /locus_tag="COSY_0810"
                     /note="Phosphoglucose isomerase (PGI) contains two SIS
                     (Sugar ISomerase) domains. This classification is based on
                     the alignment of the first SIS domain. PGI is a
                     multifunctional enzyme which as an intracellular dimer
                     catalyzes the reversible isomerization of...; Region:
                     SIS_PGI_1; cd05015"
                     /db_xref="CDD:240146"
     misc_feature    order(846560..846571,846656..846658,846668..846670,
                     846677..846679)
                     /gene="pgi"
                     /locus_tag="COSY_0810"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:240146"
     misc_feature    order(846635..846643,846650..846652,846812..846814)
                     /gene="pgi"
                     /locus_tag="COSY_0810"
                     /note="active site"
                     /db_xref="CDD:240146"
     misc_feature    847001..847510
                     /gene="pgi"
                     /locus_tag="COSY_0810"
                     /note="Phosphoglucose isomerase (PGI) contains two SIS
                     (Sugar ISomerase) domains. This classification is based on
                     the alignment of the second SIS domain. PGI is a
                     multifunctional enzyme which as an intracellular dimer
                     catalyzes the reversible isomerization of...; Region:
                     SIS_PGI_2; cd05016"
                     /db_xref="CDD:240147"
     misc_feature    order(847013..847015,847049..847051,847061..847063,
                     847070..847075,847121..847123,847127..847135,
                     847142..847147,847154..847159,847166..847168,
                     847286..847288,847292..847294,847316..847318,
                     847325..847327)
                     /gene="pgi"
                     /locus_tag="COSY_0810"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:240147"
     misc_feature    order(847049..847051,847061..847063)
                     /gene="pgi"
                     /locus_tag="COSY_0810"
                     /note="active site"
                     /db_xref="CDD:240147"
     gene            847525..848358
                     /gene="galU"
                     /locus_tag="COSY_0811"
                     /db_xref="GeneID:5171844"
     CDS             847525..848358
                     /gene="galU"
                     /locus_tag="COSY_0811"
                     /EC_number="2.7.7.9"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase"
                     /protein_id="YP_001219641.1"
                     /db_xref="GI:148244947"
                     /db_xref="GeneID:5171844"
                     /translation="MIKKCLFPAAGLGTRFLPATKAVPKEMLPILTKPLLQYAVEEAL
                     SANITNIAIVTNKNKRAIEDHFDQALELELQIKGTQKEELLKEINTVCNYATFTYVRQ
                     KQMLGLGYAILTGKALIGNEPFAVHLADDLCTSEEGNSVLYQMIKIYNKYQCSIVAIE
                     EVPMNQIHKYGVIVGDLIDNTNNTYRVTNMVEKPTPKNAPTNMAIIGRYILTPDIFNI
                     LKQTKPDKGGEIQITDALLTQSKQGNVIAYKFKGKRFDCGSIQGYIKATNYFAKLQGI
                     M"
     misc_feature    847531..848340
                     /gene="galU"
                     /locus_tag="COSY_0811"
                     /note="Prokaryotic UGPase catalyses the synthesis of
                     UDP-glucose; Region: UGPase_prokaryotic; cd02541"
                     /db_xref="CDD:133021"
     misc_feature    847534..848349
                     /gene="galU"
                     /locus_tag="COSY_0811"
                     /note="dTDP-glucose pyrophosphorylase [Cell envelope
                     biogenesis, outer membrane]; Region: RfbA; COG1209"
                     /db_xref="CDD:224130"
     misc_feature    order(847546..847557,847597..847602,847828..847830,
                     847837..847848,847906..847908,847912..847917,
                     848032..848037,848098..848103,848137..848139,
                     848221..848223)
                     /gene="galU"
                     /locus_tag="COSY_0811"
                     /note="active site"
                     /db_xref="CDD:133021"
     misc_feature    order(847558..847560,847567..847581,847585..847593,
                     847603..847611,847615..847623,847633..847635,
                     847705..847707,847711..847719,847723..847725,
                     847735..847740,847822..847827,847831..847833,
                     847837..847839,848029..848031,848209..848211,
                     848281..848283,848299..848307,848311..848319,
                     848323..848331,848338..848340)
                     /gene="galU"
                     /locus_tag="COSY_0811"
                     /note="tetramer interface; other site"
                     /db_xref="CDD:133021"
     gene            849069..849797
                     /locus_tag="COSY_0812"
                     /db_xref="GeneID:5172261"
     CDS             849069..849797
                     /locus_tag="COSY_0812"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="YP_001219642.1"
                     /db_xref="GI:148244948"
                     /db_xref="GeneID:5172261"
                     /translation="MNKVNIICIKWGDKFPVKYVNRLFGMVSRHLSIPFRFICFTENN
                     TGIRSEVEIQDLPELDLPLGLLERGWRKLTIFKNNFGNLSGSTLFLDLDIVVVGNLDE
                     FFTFPGDFLIAHDKKKPKKIEGNSSIFRFEIGKYSKILSYFEKNFELVKSEVRHEQAY
                     LSRELHKQDKLKYWPDEWVPSFKYRCCPSWIKSWFQAPFIPKNAKVILFHGLPNPPEA
                     IIGCSKKWYRHIQPSPWIEKYWKV"
     misc_feature    <849330..>849494
                     /locus_tag="COSY_0812"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cl11394"
                     /db_xref="CDD:245596"
     gene            850417..851157
                     /locus_tag="COSY_0813"
                     /db_xref="GeneID:5172300"
     CDS             850417..851157
                     /locus_tag="COSY_0813"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219643.1"
                     /db_xref="GI:148244949"
                     /db_xref="GeneID:5172300"
                     /translation="MGRKDKSKFEKWFSLTRHQRRFGAKHLSKHINVDFKHQKKQFIV
                     DDGIIYTYGSPKNIEEHSNALKNEFSGQSELCHTHAKLIILIRREFETKKHFTIFENL
                     WHEETKFLLKSLNTRWLLSAINTFADCSNNDAIIGLSVACSCLLITIEIQESERFIIN
                     SKNNKDDKEKTDRLNNEERIMLFDGISTFKFGTSDTIRNMRWRIDKAAKINVAGKILL
                     EVFKRLQKFDTIYKRAKDRHTRDKTGWW"
     gene            851158..851934
                     /locus_tag="COSY_0814"
                     /db_xref="GeneID:5172295"
     CDS             851158..851934
                     /locus_tag="COSY_0814"
                     /note="LPS biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001219644.1"
                     /db_xref="GI:148244950"
                     /db_xref="GeneID:5172295"
                     /translation="MDIFVINLSSAIKRRQFQEQQLSRLKLDYQITNATTISDINNKT
                     YQKHHYDWQRPMQKTEVACYFSHQTLWSKIVKKNRMALILEDDVLLSKHTPSILTKLE
                     KYTNFDMVNLEVFNRKKYVAKKSQPIGHHQLFYLYQDKAGAAAYVLYPNGAKKLLQQQ
                     QKSGIALADAHLHNCLELQSYQIEPACAVQLMFCKKYDIKQHSTAISQSFIRYENNNN
                     SIFVFKIKRITVQIKLGIRQLSFILKAKKRYIKLNNKDFK"
     misc_feature    851164..851673
                     /locus_tag="COSY_0814"
                     /note="Glycosyltransferase family 25 [lipooligosaccharide
                     (LOS) biosynthesis protein] is a family of
                     glycosyltransferases involved in LOS biosynthesis. The
                     members include the beta(1,4) galactosyltransferases: Lgt2
                     of Moraxella catarrhalis, LgtB and LgtE of...; Region:
                     Glyco_transf_25; cd06532"
                     /db_xref="CDD:133474"
     gene            851947..852984
                     /locus_tag="COSY_0815"
                     /db_xref="GeneID:5172277"
     CDS             851947..852984
                     /locus_tag="COSY_0815"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001219645.1"
                     /db_xref="GI:148244951"
                     /db_xref="GeneID:5172277"
                     /translation="MKKKNVAIVIPTLQGNGAERMVLTLAEGFIQQGYTVNIVLTLKR
                     SIELKSSRQLKIHYFKKYYRWIPKIIRGIFLAPILDKFIVNRCDNPNLVLSNLLPSDR
                     ILCYSKLNTYLIIHNTISKQNNNFAEMRSIYTKKPVICVSQGVKTDFDRFFNSRFPSY
                     YIYNPIDVDFINQESIKFKPKYHDYLVHVGKFKKQKRHDILIKAYHQSGIENPLILIG
                     KGHLKEKYKKLVNNLDLNEKVIFAGFQPNPYPFIKYARLMVLSSDFEGFGMVITEALA
                     LKTPVISTNCPSGPSEILPKNNLVPVNDIEKLAQLMQQANNNPLIFSHPLNKKFYLDF
                     TTKKYIDIING"
     misc_feature    851959..852906
                     /locus_tag="COSY_0815"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. WabH in Klebsiella
                     pneumoniae has been shown to transfer a GlcNAc residue
                     from UDP-GlcNAc onto the acceptor GalUA residue in the
                     cellular outer core; Region: GT1_WabH_like; cd03811"
                     /db_xref="CDD:99982"
     misc_feature    order(851995..851997,852511..852519,852688..852690,
                     852754..852756)
                     /locus_tag="COSY_0815"
                     /note="putative ADP-binding pocket [chemical binding];
                     other site"
                     /db_xref="CDD:99982"
     misc_feature    851995..852456
                     /locus_tag="COSY_0815"
                     /note="Glycosyltransferase Family 4; Region:
                     Glyco_transf_4; pfam13439"
                     /db_xref="CDD:222130"
     gene            854027..855688
                     /gene="glnS"
                     /locus_tag="COSY_0816"
                     /db_xref="GeneID:5172270"
     CDS             854027..855688
                     /gene="glnS"
                     /locus_tag="COSY_0816"
                     /EC_number="6.1.1.18"
                     /note="catalyzes a two-step reaction, first charging a
                     glutamine molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-tRNA synthetase"
                     /protein_id="YP_001219646.1"
                     /db_xref="GI:148244952"
                     /db_xref="GeneID:5172270"
                     /translation="MNKNNTYTNFIRNQIDIDLEQKLHTSIQTRFPPEPNGYLHIGHA
                     KSIFLNFGLAKDYKGRCNLRFDDTNPTKEDIKFIDAIKEDIKWLGFSWDGNIKYSSHY
                     FKQFYKYATELINKNLAYVCFLDSDEIRTYRGTLKKVGQDSPYRNTSIAKNLELLAKM
                     KAGKFLEGECVLRGKIDMRSSFMCMRDPTLYRIRFDKHHQTSNQWHIYPMYDFAHCIS
                     DAIEGVTHSLCTLEFQDNRRLYDWILENLDDFNKPNRPHQYEFSRLNLEYTVMSKRKL
                     QLLVENKLVSGWDDPRMPTISGLRRRGYTKVAIREFTNRIGISKVDNITDMKILEVAV
                     RDNLNIVAPRTMGVINPIRVIIENYPEGKLETLQSPTHPQNKTMGKRDIFFSRKLYID
                     RADFKETVPNKKFRRLAINKEVRLRSAYVINATTFDTDLNGNITTVYATYDPDTLGKN
                     PKDGRKIKGVIHFVEATKALKAEFRLYDRLFILKDLGKNNNFEQLLNTQSLIITYGMV
                     EPSMANSKPEFAYQFEREGYFCRDNQSSNKLIFNKTINLHDTWKS"
     misc_feature    854027..855682
                     /gene="glnS"
                     /locus_tag="COSY_0816"
                     /note="glutaminyl-tRNA synthetase; Provisional; Region:
                     PRK05347"
                     /db_xref="CDD:235424"
     misc_feature    854105..>854422
                     /gene="glnS"
                     /locus_tag="COSY_0816"
                     /note="nucleotidyl transferase superfamily; Region:
                     nt_trans; cl00015"
                     /db_xref="CDD:241550"
     misc_feature    854144..854155
                     /gene="glnS"
                     /locus_tag="COSY_0816"
                     /note="active site"
                     /db_xref="CDD:173912"
     misc_feature    854144..854155
                     /gene="glnS"
                     /locus_tag="COSY_0816"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173912"
     misc_feature    order(854144..854146,854153..854155)
                     /gene="glnS"
                     /locus_tag="COSY_0816"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173912"
     misc_feature    <854618..855058
                     /gene="glnS"
                     /locus_tag="COSY_0816"
                     /note="catalytic core domain of glutaminyl-tRNA
                     synthetase; Region: GlnRS_core; cd00807"
                     /db_xref="CDD:185676"
     misc_feature    854834..854848
                     /gene="glnS"
                     /locus_tag="COSY_0816"
                     /note="KMSKS motif; other site"
                     /db_xref="CDD:185676"
     misc_feature    855050..855622
                     /gene="glnS"
                     /locus_tag="COSY_0816"
                     /note="tRNA synthetases class I (E and Q), anti-codon
                     binding domain; Region: tRNA-synt_1c_C; pfam03950"
                     /db_xref="CDD:217810"
     gene            complement(856135..856884)
                     /gene="surE"
                     /locus_tag="COSY_0817"
                     /db_xref="GeneID:5172701"
     CDS             complement(856135..856884)
                     /gene="surE"
                     /locus_tag="COSY_0817"
                     /EC_number="3.1.3.2"
                     /note="catalyzes the conversion of a phosphate monoester
                     to an alcohol and a phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase survival protein SurE"
                     /protein_id="YP_001219647.1"
                     /db_xref="GI:148244953"
                     /db_xref="GeneID:5172701"
                     /translation="MKILVSNDDGYQAQGIIELAQSLAQEHEVIVVAPSENKSAASSS
                     LTLDKPLRPIQISNNVYCIDATPSDCVHLALCGFLNEEIDLVVTGINFGANLGDDVIY
                     SGTVAGAIEGRFLGLPSLSISLASWRGQHFKTAGIVIRQLINQISHAHLSYGTVLNIN
                     VPDVIFSDIKGFQTTRLGKRHMSEQSVIDKNDSSLYWIGENGKEADNGVGTDFHAITN
                     HYVSITPLQTDLTKYNEINTVSTWLNQIITT"
     misc_feature    complement(856153..856884)
                     /gene="surE"
                     /locus_tag="COSY_0817"
                     /note="5&apos;(3&apos;)-nucleotidase/polyphosphatase;
                     Provisional; Region: surE; PRK00346"
                     /db_xref="CDD:234732"
     gene            complement(856907..859129)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /db_xref="GeneID:5172228"
     CDS             complement(856907..859129)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="YP_001219648.1"
                     /db_xref="GI:148244954"
                     /db_xref="GeneID:5172228"
                     /translation="MIETGLQQEINYVMTQARNNRLEFVTVEHLLLALLNIDEMVTLL
                     NNKRVDVDEFRDELEGYIDSHTPLIALDSNVDIVLTVGFQRVLQRSIYQVQSAQKNTV
                     YAMNILVSIFSEKDSHSVYLLKLNNISRLDAMEDILNRTPESITSEPRVESDKEKIKQ
                     SSLETYTTNLCEKAKSGQIDPLLGREKEIIRTVQVLSRRRKNNLLFVGLSGVGKTAIA
                     QGIALKIVEGKVPDILKKVSIYSLDIGVLIAGTKYRGDFEKRLKAVLTDLEKIPKAVL
                     FIDEIHTLIGAGSVSGGSLDASNLLKPALADGTLRCMGSTTYEEYRKVFEKDHALSRR
                     FQKIDIDEPSVADTIKILQGLKKYYQNYHKVKYSAAALRSAVELSHRYINNRYLPDKA
                     IDVIDEVGAYQQIQPKSKRKINIGVGDIENIISKLARIPSNKVTNDDKFLLKNLESEL
                     KLGVFGQDRALDSLSTAIKLSRSGLAQVDKPIGSFLFAGPTGVGKTEICKQLARIMGI
                     KLLRFDMSEYGERHSVSKFIGSPPGYVGYDKGGLLTEVVNANPHAVLLLDEIEKAHAD
                     IFNLLLQVMDNSKMTDASGREVDFRNVILVMTSNAGVQSIQRASIGFSEQDRSLDYET
                     ELKKLFTPEFRNRLSEVIYFNTLNEQTIVYVVNKFLFELKKALENKQVSLTVSDIARA
                     WFAKHGYDAKMGARPMARLVEQEIRKPLADELLFGKLTNGGLVKVDVKKDRIILVIQS
                     "
     misc_feature    complement(856943..859114)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="ATP-dependent Clp protease ATP-binding subunit
                     clpA; Region: ClpA; TIGR02639"
                     /db_xref="CDD:233959"
     misc_feature    complement(858941..859081)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="Clp amino terminal domain; Region: Clp_N;
                     pfam02861"
                     /db_xref="CDD:217254"
     misc_feature    complement(858116..858580)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(858485..858508)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(858179..858181,858293..858295,
                     858482..858505))
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(858290..858307)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(858128..858130)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(857330..857767)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(857642..857665)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(857330..857332,857456..857458,
                     857639..857662))
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(857453..857470)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(856949..857191)
                     /gene="clpA"
                     /locus_tag="COSY_0818"
                     /note="C-terminal, D2-small domain, of ClpB protein;
                     Region: ClpB_D2-small; pfam10431"
                     /db_xref="CDD:204486"
     gene            complement(859346..860428)
                     /locus_tag="COSY_0819"
                     /db_xref="GeneID:5172104"
     CDS             complement(859346..860428)
                     /locus_tag="COSY_0819"
                     /note="YjgP/YjgQ family"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="YP_001219649.1"
                     /db_xref="GI:148244955"
                     /db_xref="GeneID:5172104"
                     /translation="MKILTLYIVKTMAFYTLIVMLVWIGVYSFFNFLDEVKFIGQYNY
                     TVFEATKYIILNIPAVMYSHSSVIILLGSLLALTNLASTSQLVIIRSSGVSIMQISNI
                     VVWVALMFIAIIILIGELVAPITTEYAECLRSKALEQNMTCRNQQEFWLKDNGLFIHV
                     KKDFDAKSFQDITFIKLRAPGVLDSIIYSDNATFNGNNLELNKPIHYQLSKNGELTTF
                     SKNYFEKYSVQISFNQKLIKNLKKDPRKLSTWHLYKQMSFLTNNNLVADIVEIEIYKR
                     FMMPVTLVAMILFSMLFVFGSLRDASLGKKIFLGLMMSLFFELASRIIGVLSLTFNYN
                     HFLSASIPTLMVLVIVLLLLKRKSAN"
     misc_feature    complement(859403..860428)
                     /locus_tag="COSY_0819"
                     /note="Predicted permeases [General function prediction
                     only]; Region: COG0795; cl12074"
                     /db_xref="CDD:245860"
     misc_feature    complement(859400..860410)
                     /locus_tag="COSY_0819"
                     /note="Predicted permease YjgP/YjgQ family; Region:
                     YjgP_YjgQ; pfam03739"
                     /db_xref="CDD:217705"
     gene            860473..862038
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /db_xref="GeneID:5172264"
     CDS             860473..862038
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /EC_number="6.3.5.2"
                     /note="contains glutamine-hydrolyzing domain and glutamine
                     amidotransferase; GMP-binding domain; functions to produce
                     GMP from XMP in the IMP pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP synthase"
                     /protein_id="YP_001219650.1"
                     /db_xref="GI:148244956"
                     /db_xref="GeneID:5172264"
                     /translation="MMNNIHLNKILILDFGSQYTQLIARRVREIGVYCELSHYDINSD
                     FIKKFNPKGVILSGGPDTVTFDNSARAPSIIFDLNIPILGICYGMQTMAIQLGGHATS
                     ADKHEYGFAKVRSCNYSPLLNGINDGGDDLLDVWMSHGIEVKRLPDGFKLIASTDSCN
                     IAGFADINKHYYGLQFHPEVTHTKQGKHILERFVSDICQCKKNWTTDNIITKLVKDLK
                     NQIGSANVLLGLSGGVDSSVVAILLQQAVGKQLTCVFVDNGLLRLNEGNKIMQTFAQN
                     MSVKVIRVNAQEKFYNALSNEDKPEAKRKIIGHAFIEVFEEEARKLNNIQFLAQGTIY
                     PDVIESAGTKSNKTKVIKSHHNVGGLPNSLQLTLVEPIKELFKDEVRKIGVILGLPTH
                     MLNCHPFPGPGLSIRILGQVKQEYVDILRQADTIFIDELYKNNLYNTVNQAFAVFLPI
                     KSVGVTGDARRYDYVISLRAVETIDFMTARWARLPYDFLDLVSNRIMNEIPRISRVVY
                     DISSKPPATIEWE"
     misc_feature    860485..862035
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /note="GMP synthase; Reviewed; Region: guaA; PRK00074"
                     /db_xref="CDD:234614"
     misc_feature    860500..861054
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in GMP synthetase; Region: GATase1_GMP_Synthase;
                     cd01742"
                     /db_xref="CDD:153213"
     misc_feature    order(860521..860526,860644..860652,860728..860733,
                     860884..860886,861001..861003)
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /note="AMP/PPi binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:153213"
     misc_feature    order(860647..860649,860731..860733)
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /note="candidate oxyanion hole; other site"
                     /db_xref="CDD:153213"
     misc_feature    order(860728..860730,861001..861003,861007..861009)
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153213"
     misc_feature    order(860740..860742,860887..860889,860995..860997)
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /note="potential glutamine specificity residues [chemical
                     binding]; other site"
                     /db_xref="CDD:153213"
     misc_feature    861148..862032
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /note="The C-terminal domain of GMP synthetase. It
                     contains two subdomains; the ATP pyrophosphatase domain
                     which closes to the N-termial and the dimerization domain
                     at C-terminal end. The ATP-PPase is a twisted,
                     five-stranded parallel beta-sheet sandwiched...; Region:
                     GMP_synthase_C; cd01997"
                     /db_xref="CDD:238955"
     misc_feature    order(861148..861219,861223..861255,861259..861291,
                     861322..861435,861451..861498,861526..861555,
                     861568..861642,861658..861702)
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /note="ATP Binding subdomain [chemical binding]; other
                     site"
                     /db_xref="CDD:238955"
     misc_feature    order(861157..861165,861169..861180,861232..861234,
                     861238..861240,861601..861603)
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /note="Ligand Binding sites [chemical binding]; other
                     site"
                     /db_xref="CDD:238955"
     misc_feature    order(861727..861765,861790..861819,861826..861858,
                     861868..861915,861934..861960,861964..862032)
                     /gene="guaA"
                     /locus_tag="COSY_0820"
                     /note="Dimerization subdomain; other site"
                     /db_xref="CDD:238955"
     gene            862029..862490
                     /locus_tag="COSY_0821"
                     /db_xref="GeneID:5171826"
     CDS             862029..862490
                     /locus_tag="COSY_0821"
                     /note="cytidine/deoxycytidylate deaminase, zinc-binding
                     region"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219651.1"
                     /db_xref="GI:148244957"
                     /db_xref="GeneID:5171826"
                     /translation="MGINTVAWMTLAIEQAKQAQQIGEIPVGAILIQNNQLIGGAHNQ
                     TILNNDPTAHAEIQLLRIAGKKLNNYRLSGTTLYVTLEPCTMCLGAIVHARISCIVFG
                     AYDKKSGACGSCIDLLNNRCFNHLISIKSGILADQCKNLLQDFFKNKRKNT"
     misc_feature    862053..862376
                     /locus_tag="COSY_0821"
                     /note="Nucleoside deaminases include adenosine, guanine
                     and cytosine deaminases. These enzymes are Zn dependent
                     and catalyze the deamination of nucleosides. The zinc ion
                     in the active site plays a central role in the proposed
                     catalytic mechanism, activating a...; Region:
                     nucleoside_deaminase; cd01285"
                     /db_xref="CDD:238612"
     misc_feature    order(862107..862109,862155..862157,862188..862196,
                     862278..862280,862287..862289)
                     /locus_tag="COSY_0821"
                     /note="nucleoside/Zn binding site; other site"
                     /db_xref="CDD:238612"
     misc_feature    order(862182..862184,862197..862199,862209..862211,
                     862281..862286,862293..862298,862305..862310)
                     /locus_tag="COSY_0821"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238612"
     misc_feature    order(862188..862196,862275..862280,862287..862289)
                     /locus_tag="COSY_0821"
                     /note="catalytic motif [active]"
                     /db_xref="CDD:238612"
     gene            complement(862508..863254)
                     /gene="fabG"
                     /locus_tag="COSY_0822"
                     /db_xref="GeneID:5172254"
     CDS             complement(862508..863254)
                     /gene="fabG"
                     /locus_tag="COSY_0822"
                     /EC_number="1.1.1.100"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier protein] reductase"
                     /protein_id="YP_001219652.1"
                     /db_xref="GI:148244958"
                     /db_xref="GeneID:5172254"
                     /translation="MNNLDGKIVLVTGASRGIGQAIALTLGAAGATVIGTATSNKGSS
                     AISIVLKNSGVTGIGMKLNVTNNEQIAKMIKSIVGTYGIIDILVNNAGIIRDNLLMRM
                     CEDEWDDIINTNLTSVYKMSKAVLRGMMKKKSGRIISIASVVGAMGNAGQTNYAAAKA
                     GIIGFTKSLAREVGSRNITINAIAPGFIETDMINTLSEEQIVAVSQQIPMNRLGTVYE
                     VANAVLFLAGNGGAYITAQTLHVNGGMYAV"
     misc_feature    complement(862511..863248)
                     /gene="fabG"
                     /locus_tag="COSY_0822"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Validated; Region: fabG; PRK05557"
                     /db_xref="CDD:235500"
     misc_feature    complement(862517..863236)
                     /gene="fabG"
                     /locus_tag="COSY_0822"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    complement(order(862691..862702,862778..862780,
                     862790..862792,862829..862837,862979..862987,
                     863138..863146,863201..863203,863207..863212,
                     863216..863218))
                     /gene="fabG"
                     /locus_tag="COSY_0822"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    complement(order(862778..862780,862790..862792,
                     862829..862831,862913..862915))
                     /gene="fabG"
                     /locus_tag="COSY_0822"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            complement(863251..864183)
                     /gene="fabD"
                     /locus_tag="COSY_0823"
                     /db_xref="GeneID:5172496"
     CDS             complement(863251..864183)
                     /gene="fabD"
                     /locus_tag="COSY_0823"
                     /EC_number="2.3.1.39"
                     /note="malonyl-CoA-[acyl-carrier-protein] transacylase"
                     /codon_start=1
                     /transl_table=11
                     /product="[acyl-carrier-protein] S-malonyltransferase"
                     /protein_id="YP_001219653.1"
                     /db_xref="GI:148244959"
                     /db_xref="GeneID:5172496"
                     /translation="MKYAIIFPGQGSQSLGMLSELASYFPVVKETFTEASDALGFDLW
                     TLTQQDRNALNQTQNTQPAMLAAGYATYLALTYKYNLLPICMAGHSLGEYTALVASGS
                     LGFSDGIKLVRKRAELMQSAMPKGVGVMAAILGLESSVVVKLCLDYSGSGIVEAVNFN
                     SLRQVVIAGNKEAVEATCQLLKIRGAKRVVLLPVSVASHCSLMNDAAVEFKNYVDVVR
                     FNQGSIDVLHNFDTLKATDVDDIKSKLVAQLHNPVLWTSTIQAMHNMGIEKLIESGPG
                     KVLTGLTKRIEKSLTVNAILDPTSIEITLKEILS"
     misc_feature    complement(863263..864183)
                     /gene="fabD"
                     /locus_tag="COSY_0823"
                     /note="(acyl-carrier-protein) S-malonyltransferase [Lipid
                     metabolism]; Region: FabD; COG0331"
                     /db_xref="CDD:223408"
     misc_feature    complement(863314..864183)
                     /gene="fabD"
                     /locus_tag="COSY_0823"
                     /note="malonyl CoA-acyl carrier protein transacylase;
                     Region: fabD; TIGR00128"
                     /db_xref="CDD:232839"
     gene            complement(864271..864528)
                     /gene="rpmA"
                     /locus_tag="COSY_0824"
                     /db_xref="GeneID:5172495"
     CDS             complement(864271..864528)
                     /gene="rpmA"
                     /locus_tag="COSY_0824"
                     /note="involved in the peptidyltransferase reaction during
                     translation"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="YP_001219654.1"
                     /db_xref="GI:148244960"
                     /db_xref="GeneID:5172495"
                     /translation="MAHKKAGGSTNNGRDSVSKRLGVKRFGGQVVLAGNILVRQRGTK
                     FHPGTNVRKGKDDTLFATMDGRVVFSKKGKFMYQYISIEIT"
     misc_feature    complement(864280..864528)
                     /gene="rpmA"
                     /locus_tag="COSY_0824"
                     /note="50S ribosomal protein L27; Validated; Region: rpmA;
                     PRK05435"
                     /db_xref="CDD:235464"
     gene            complement(864540..864851)
                     /gene="rplU"
                     /locus_tag="COSY_0825"
                     /db_xref="GeneID:5172720"
     CDS             complement(864540..864851)
                     /gene="rplU"
                     /locus_tag="COSY_0825"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="YP_001219655.1"
                     /db_xref="GI:148244961"
                     /db_xref="GeneID:5172720"
                     /translation="MYAVIKTGGQQFKVKQGTILKIEKLEIEPGKKVTFKEVLIVSDG
                     DDIQVGTPFVSKVTVEAKIISQGKGKKVHILKFRRRKHSMKQQGHRQLLTEIEIVKIN
                     A"
     misc_feature    complement(<864543..864851)
                     /gene="rplU"
                     /locus_tag="COSY_0825"
                     /note="50S ribosomal protein L21/unknown domain fusion
                     protein; Provisional; Region: PRK12278"
                     /db_xref="CDD:237034"
     misc_feature    complement(864543..864851)
                     /gene="rplU"
                     /locus_tag="COSY_0825"
                     /note="50S ribosomal protein L21; Validated; Region: rplU;
                     PRK05573"
                     /db_xref="CDD:235510"
     gene            864977..865462
                     /gene="ppiB"
                     /locus_tag="COSY_0826"
                     /db_xref="GeneID:5172629"
     CDS             864977..865462
                     /gene="ppiB"
                     /locus_tag="COSY_0826"
                     /EC_number="5.2.1.8"
                     /note="rotamase"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase B"
                     /protein_id="YP_001219656.1"
                     /db_xref="GI:148244962"
                     /db_xref="GeneID:5172629"
                     /translation="MTIFETNMGNIHINVDIKNTPISAQNFIDYVNNRFYDGTIFHRV
                     IKDFMIQGGGFTKDMIQKTTKTNIKNEAKNSFKNNKYSLAMARTSAPHSASSQFFINT
                     SKNSYLDFPGQDGWGYCVFGKVVKGFEVIDKINQVSTSNKDEHSDIPNDSVIVNRAYN
                     A"
     misc_feature    864977..865447
                     /gene="ppiB"
                     /locus_tag="COSY_0826"
                     /note="cyclophilin: cyclophilin-type peptidylprolyl cis-
                     trans isomerases. This family contains eukaryotic,
                     bacterial and archeal proteins which exhibit a
                     peptidylprolyl cis- trans isomerases activity (PPIase,
                     Rotamase) and in addition bind the...; Region:
                     cyclophilin; cl00197"
                     /db_xref="CDD:241677"
     misc_feature    order(865103..865105,865109..865111,865118..865123,
                     865127..865129,865232..865237,865265..865267,
                     865271..865273,865295..865300,865313..865315)
                     /gene="ppiB"
                     /locus_tag="COSY_0826"
                     /note="active site"
                     /db_xref="CDD:238194"
     gene            865465..866187
                     /gene="lpxH"
                     /locus_tag="COSY_0827"
                     /db_xref="GeneID:5171819"
     CDS             865465..866187
                     /gene="lpxH"
                     /locus_tag="COSY_0827"
                     /EC_number="3.6.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine hydrolase"
                     /protein_id="YP_001219657.1"
                     /db_xref="GI:148244963"
                     /db_xref="GeneID:5171819"
                     /translation="MSQIFIIADLHLTVNKIEKTHLFIKFCQEQAVIADQLFILGDLF
                     HTWLGDDLSINYYQKVILTLKKLSLKTKIFIMTGNRDFLLGNNFVKQTNCILINTPYL
                     LKTSKQQYLLTHGDELCTDDKKYQRLKRVLQHPITKFIFLHLKTKLRIKISNKLRQNS
                     IKAQQSKSLKVMDVNMTSVNQLMQKYPGVNLIHGHTHRLDTHVNNNFTRYVLGEWSNN
                     QGNAIKINHQQLNRLKISTTIN"
     misc_feature    865477..866109
                     /gene="lpxH"
                     /locus_tag="COSY_0827"
                     /note="Escherichia coli YbbF/LpxH and related proteins,
                     metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398"
                     /db_xref="CDD:163641"
     misc_feature    865483..>866097
                     /gene="lpxH"
                     /locus_tag="COSY_0827"
                     /note="Predicted phosphohydrolases [General function
                     prediction only]; Region: Icc; COG1409"
                     /db_xref="CDD:224327"
     misc_feature    order(865489..865491,865495..865497,865588..865590,
                     865699..865704,865804..865806,866047..866049,
                     866053..866055)
                     /gene="lpxH"
                     /locus_tag="COSY_0827"
                     /note="putative active site [active]"
                     /db_xref="CDD:163641"
     misc_feature    order(865489..865491,865495..865497,865588..865590,
                     865699..865701,865804..865806,866047..866049,
                     866053..866055)
                     /gene="lpxH"
                     /locus_tag="COSY_0827"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:163641"
     gene            complement(866152..867957)
                     /locus_tag="COSY_0828"
                     /db_xref="GeneID:5172259"
     CDS             complement(866152..867957)
                     /locus_tag="COSY_0828"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease II family protein"
                     /protein_id="YP_001219658.1"
                     /db_xref="GI:148244964"
                     /db_xref="GeneID:5172259"
                     /translation="MINALVSYKGKPARIIKQTIHKFVLEFADGSSRLVRAKDFRFIH
                     SEFVQVDNTCTYADVSVLEDLQEEVLTLEEVTQWLFDEYNAKNAWCSCVLIEDGLYFY
                     WQKDKVFIRPTYQVESIRTKRDAKIIETKNLKHCADNIANNILDKQDLPYIRDIEKVA
                     LNQSKHAKVLSNIGIENIPESAYRLLLNLNYFKPGFNPYPTRNNILKDDQIDASIVKV
                     DRVDLTHLSSYAIDNFDSNDADDAISVDGDKIWIHIADVSLIATAGSELDSYAQKRAS
                     NLYLPEQIIHMLPISVTKMCALGLTETSHALSIGFTLELGEINNVEVVRSIIKVTNIS
                     YDNADGMLVSNEYLSKLQSITKAHKQYRYKNGAISLNLPNVDIRFRQGQVLITQQRLS
                     KSRELVAEMMVMAGRVVAQFAVDNNIVMPYTIQDKGGFSQEILDNQDTLSLSESFKAT
                     KFFKRSATSIKNLPHFGLGVKAYLRITSPLRRYLDLFAHQQLSRFIKGEDTLNKEDVK
                     KIIGIHNTTMSSVGRTIRSSNDHYKCVYLLDNPLWQGDSFVVDIRGNKTLLMIPELGM
                     ITQIRFKILPKLDEKITLKVTTVDLVDCSANFKSI"
     misc_feature    complement(866464..867300)
                     /locus_tag="COSY_0828"
                     /note="This domain is the catalytic domain of ribonuclease
                     II; Region: RNB; smart00955"
                     /db_xref="CDD:214935"
     misc_feature    complement(866470..867300)
                     /locus_tag="COSY_0828"
                     /note="RNB domain; Region: RNB; pfam00773"
                     /db_xref="CDD:216112"
     gene            complement(867966..868340)
                     /gene="gcvH"
                     /locus_tag="COSY_0829"
                     /db_xref="GeneID:5172246"
     CDS             complement(867966..868340)
                     /gene="gcvH"
                     /locus_tag="COSY_0829"
                     /note="part of multienzyme complex composed of H, L, P,
                     and T proteins which catalyzes oxidation of glycine to
                     yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a
                     reduced pyridine nucleotide; protein H is involved in
                     transfer of methylamine group from the P to T protein;
                     covalently bound to a lipoyl cofactor"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="YP_001219659.1"
                     /db_xref="GI:148244965"
                     /db_xref="GeneID:5172246"
                     /translation="MSEIRDDRQYTQTHEWILDNGDDTYTMGITDHAQALLGDMVFVE
                     LPNVDDEVSIDDEFCVVESVKAASGVYSPADLQIIEANEALDDEPELVNSSCYDDGWL
                     VKFKSHSVVDLMDSTAYAQILN"
     misc_feature    complement(868026..868313)
                     /gene="gcvH"
                     /locus_tag="COSY_0829"
                     /note="Glycine cleavage H-protein. Glycine cleavage
                     H-proteins are part of the glycine cleavage system (GCS)
                     found in bacteria, archea and the mitochondria of
                     eukaryotes. GCS is a multienzyme complex consisting of 4
                     different components (P-, H-, T- and...; Region: GCS_H;
                     cd06848"
                     /db_xref="CDD:133457"
     misc_feature    complement(868146..868148)
                     /gene="gcvH"
                     /locus_tag="COSY_0829"
                     /note="lipoyl attachment site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133457"
     gene            complement(868384..869460)
                     /gene="gcvT"
                     /locus_tag="COSY_0830"
                     /db_xref="GeneID:5171903"
     CDS             complement(868384..869460)
                     /gene="gcvT"
                     /locus_tag="COSY_0830"
                     /EC_number="2.1.2.10"
                     /note="catalyzes the transfer of a methylene carbon from
                     the methylamine-loaded GcvH protein to tetrahydrofolate,
                     causing the release of ammonia and the generation of
                     reduced GcvH protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     T"
                     /protein_id="YP_001219660.1"
                     /db_xref="GI:148244966"
                     /db_xref="GeneID:5171903"
                     /translation="MKQTPLYQIHVESQGNMVDFWDWKMPLNYGSQIEEHHQVRHDAG
                     MFDISHMSVVDFKGVEAKAFLQVLIANDVDKLRVQGKALYGCMLNELGGIVDDLIVYC
                     RNNEYYRMVINARTTDKDMAWINTQANSFDVLVEPISDLAMIAVQGPNAREKVFSAIP
                     GVEEVCGELKSFNAASLGKLFIARIGYTGEDGFEIMLPLNAAKFTWKMLLEAGVKPYG
                     LGAFDTLRLEAGVSLYGLEMNDMVSPLEAALAWTVDLSNENRAFIGRDALETLKDKGV
                     KKTIIGLVLEGKGVIRNHQKVMTSLGEGKVTSGIFSPTIGKAIALASVPKGSLGVCEI
                     EIRKRQVYAKIVEPPFVRNGIVLV"
     misc_feature    complement(868399..869460)
                     /gene="gcvT"
                     /locus_tag="COSY_0830"
                     /note="glycine cleavage system aminomethyltransferase T;
                     Reviewed; Region: gcvT; PRK00389"
                     /db_xref="CDD:234742"
     misc_feature    complement(868417..868677)
                     /gene="gcvT"
                     /locus_tag="COSY_0830"
                     /note="Glycine cleavage T-protein C-terminal barrel
                     domain; Region: GCV_T_C; pfam08669"
                     /db_xref="CDD:219963"
     gene            complement(869460..870113)
                     /gene="ispZ"
                     /locus_tag="COSY_0831"
                     /db_xref="GeneID:5172222"
     CDS             complement(869460..870113)
                     /gene="ispZ"
                     /locus_tag="COSY_0831"
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular septation protein"
                     /protein_id="YP_001219661.1"
                     /db_xref="GI:148244967"
                     /db_xref="GeneID:5172222"
                     /translation="MNKFLLEFFPIILFFVVYKVMGLYMAIYAMISATFLQMIIVRFQ
                     IGRFENTHLITFGLLGVLGGVTLVLRDPAFLMWKVSVLYVVFAFMLVLSMWIGKKTLL
                     QRMLGKELDLPINVWCQLSWLWGFGFIGIAIVNAYYVNIALSAREALFTSTELDPKIE
                     LTMLDCTNIAMSNLCIIAQEAEESWVNFKLFGTMGLTLILIIIMIIFIKKYIKEDKK"
     misc_feature    complement(<869703..870068)
                     /gene="ispZ"
                     /locus_tag="COSY_0831"
                     /note="Intracellular septation protein A; Region: IspA;
                     cl01098"
                     /db_xref="CDD:242299"
     gene            complement(870114..870323)
                     /locus_tag="COSY_0832"
                     /db_xref="GeneID:5172523"
     CDS             complement(870114..870323)
                     /locus_tag="COSY_0832"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219662.1"
                     /db_xref="GI:148244968"
                     /db_xref="GeneID:5172523"
                     /translation="MGIIKLIIIVLFVWMGFWLLKKFRKPIDRIKQKSSSNIMLACSV
                     CKIHIPRNEAIIQNNKAYCSKEHLE"
     gene            870408..870495
                     /locus_tag="COSY_t31"
                     /db_xref="GeneID:5329739"
     tRNA            870408..870495
                     /locus_tag="COSY_t31"
                     /product="tRNA-Leu"
                     /db_xref="GeneID:5329739"
     gene            870701..871108
                     /locus_tag="COSY_0834"
                     /db_xref="GeneID:5172235"
     CDS             870701..871108
                     /locus_tag="COSY_0834"
                     /note="YjgF-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease L-PSP family protein"
                     /protein_id="YP_001219663.1"
                     /db_xref="GI:148244969"
                     /db_xref="GeneID:5172235"
                     /translation="MQKQIISTNKAPKAIGTYSQAVCITGGSIIYLSGQIPLIPATME
                     IINGDIGEQINQVFKNLIAVCRQSNGDLKDIVKLNIYLTDLNNFPKVNKIMSTYFNEP
                     YPARAMIGVNELPKKSMVEIDGVMVIEPYDYTY"
     misc_feature    870752..871075
                     /locus_tag="COSY_0834"
                     /note="YjgF, YER057c, and UK114 belong to a large family
                     of proteins present in bacteria, archaea, and eukaryotes
                     with no definitive function. The conserved domain is
                     similar in structure to chorismate mutase but there is no
                     sequence similarity and no...; Region:
                     YjgF_YER057c_UK114_family; cd00448"
                     /db_xref="CDD:100004"
     misc_feature    order(870752..870757,870764..870766,870770..870772,
                     870785..870787,870791..870793,870797..870802,
                     870920..870922,870926..870931,870935..870937,
                     870941..870943,870974..870976,870983..870985,
                     871010..871033,871061..871063,871067..871069,
                     871073..871075)
                     /locus_tag="COSY_0834"
                     /note="homotrimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:100004"
     misc_feature    order(870752..870754,870962..870964,870974..870976,
                     871016..871018,871061..871063)
                     /locus_tag="COSY_0834"
                     /note="putative active site [active]"
                     /db_xref="CDD:100004"
     gene            871179..873245
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /db_xref="GeneID:5172220"
     CDS             871179..873245
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /EC_number="3.6.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="YP_001219664.1"
                     /db_xref="GI:148244970"
                     /db_xref="GeneID:5172220"
                     /translation="MYQLSNSIIILDGLGPKTQQKLNAIGIFNLEHLLFQLPTHYQDK
                     TKLAKLNQVQIGDEVLIQLTIKYTEQVSTHQKQLLCYLSDSNHRNLLLRFFYFNQYQK
                     QNFIRGDIIQCFGEIKMGQNSLEIHNPEYRLISKGQANLLEKTLSPIYPLTANIRQAQ
                     MKKWIDTALEVLQQSDLFDNFKNLTNNTMPTLKQALNTLHHPKVDDNIKQIANFKHFS
                     QQRLIIEELCTQRLSLLKLKSKRKSKISNIFKIKNRLTQKALDTLKFQLTQAQQSCIN
                     DINSDLSSNHPMLRLLQGDVGSGKTIIAVFACLQAIENGFQTTIIAPTEILAAQHLQG
                     FSNYLTPLGIDIAFLTDSQSAIQKSKQLEKINSDTARIIIGTHVLLQTKVVFDKLGLV
                     IINEQHKFGVHQCLSLVQKSHNTPHQLVITATPIPKSLTISVYADLDYSIIDELPTGR
                     TPTNTIVLGNDKKNKVIEKIKQVCNIGNQVYWVCTLIEESEVLRTESATNTHNYLKKN
                     LEGLTVVLINGRMQKYKKSNIIAQFLKGEIDVLVATTEIEAGVNIINTSLLVIENSER
                     LGLTQLHQLRSRVGRSLDASICILMYQAPLSYNAIERLDILRKTNDGFKIALKDLELR
                     GPSEILGTQQIGITNMKIANIVRDRYLLKQVQSYSKQFLKLDKNKQQILITRWITNDN
                     STYSNI"
     misc_feature    871179..873221
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /note="ATP-dependent DNA helicase RecG; Provisional;
                     Region: PRK10917"
                     /db_xref="CDD:236794"
     misc_feature    871359..871580
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /note="RecG_wedge_OBF: A subfamily of OB folds
                     corresponding to the OB fold found in the N-terminal
                     (wedge) domain of Escherichia coli RecG. RecG is a
                     branched-DNA-specific helicase, which catalyzes the
                     interconversion of a DNA replication fork to a...; Region:
                     RecG_wedge_OBF; cd04488"
                     /db_xref="CDD:239934"
     misc_feature    order(871389..871391,871407..871409,871461..871463,
                     871476..871478,871554..871556)
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /note="ssDNA binding site; other site"
                     /db_xref="CDD:239934"
     misc_feature    order(871506..871508,871512..871514,871518..871520,
                     871575..871577)
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /note="generic binding surface II; other site"
                     /db_xref="CDD:239934"
     misc_feature    872046..872453
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /note="DEAD-like helicases superfamily. A diverse family
                     of proteins involved in ATP-dependent RNA or DNA
                     unwinding. This domain contains the ATP-binding region;
                     Region: DEXDc; cd00046"
                     /db_xref="CDD:238005"
     misc_feature    872067..872081
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238005"
     misc_feature    872361..872372
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /note="putative Mg++ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238005"
     misc_feature    872535..872951
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:238034"
     misc_feature    order(872631..872633,872658..872666,872730..872735,
                     872808..872816)
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:238034"
     misc_feature    order(872832..872834,872898..872900,872910..872912,
                     872919..872921)
                     /gene="recG"
                     /locus_tag="COSY_0835"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238034"
     gene            873277..873741
                     /gene="ubiC"
                     /locus_tag="COSY_0836"
                     /db_xref="GeneID:5171893"
     CDS             873277..873741
                     /gene="ubiC"
                     /locus_tag="COSY_0836"
                     /EC_number="4.1.3.-"
                     /note="4-hydroxybenzoate synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate--pyruvate lyase"
                     /protein_id="YP_001219665.1"
                     /db_xref="GI:148244971"
                     /db_xref="GeneID:5171893"
                     /translation="MFNTKNLIWTNLNQIRNIPDHILTWLDDYQSLTAKLKQKFNRFS
                     VNILSQKKSIPHADEIELLDWHSQFVVREVELLGNDQVIVFARSIIPITDNTQRLLKI
                     GSHPLGEMLFNDINIKRGQLQITHTHGTWGRRSIFTIGSTQVLVSEFFIKDS"
     misc_feature    873292..873729
                     /gene="ubiC"
                     /locus_tag="COSY_0836"
                     /note="Chorismate lyase; Region: Chor_lyase; cl01230"
                     /db_xref="CDD:242378"
     gene            874189..874776
                     /locus_tag="COSY_0837"
                     /db_xref="GeneID:5171981"
     CDS             874189..874776
                     /locus_tag="COSY_0837"
                     /EC_number="2.6.1.85"
                     /note="Similar to the N-terminal region of bifunctional
                     protein TrpD (531 aa) in Escherichia coli, anthranilate
                     phosphoribosyltransferase / anthranilate synthase
                     component II (EC:2.4.2.18 EC:4.1.3.27)."
                     /codon_start=1
                     /transl_table=11
                     /product="para-aminobenzoate synthetase component II"
                     /protein_id="YP_001219666.1"
                     /db_xref="GI:148244972"
                     /db_xref="GeneID:5171981"
                     /translation="MLLMIDNYDSFTYNLVQYFGELGQAVEVYRNDEITIQEIEKLMP
                     EFLVISPGPYAPNEAGISIEAIKYFSKKIPILGVCLGFQAIVQTFGGNIIGAKKIMHG
                     KVSKIYHTNKGVFTSLKNPLNATRYHSLVAQQSTLPKCFEVTSWTKNNKGEVDEIMGV
                     RHKEFATEGVQFHPESILTEQGHEILNNFLIRRAL"
     misc_feature    874189..874767
                     /locus_tag="COSY_0837"
                     /note="para-aminobenzoate synthase component II;
                     Provisional; Region: PRK08857"
                     /db_xref="CDD:181566"
     misc_feature    874192..874758
                     /locus_tag="COSY_0837"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in Anthranilate synthase; Region:
                     GATase1_Anthranilate_Synthase; cd01743"
                     /db_xref="CDD:153214"
     misc_feature    order(874339..874344,874348..874350,874423..874428,
                     874435..874437,874567..874578)
                     /locus_tag="COSY_0837"
                     /note="glutamine binding [chemical binding]; other site"
                     /db_xref="CDD:153214"
     misc_feature    order(874423..874425,874705..874707,874711..874713)
                     /locus_tag="COSY_0837"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153214"
     gene            874780..875199
                     /locus_tag="COSY_0838"
                     /db_xref="GeneID:5172213"
     CDS             874780..875199
                     /locus_tag="COSY_0838"
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese family protein"
                     /protein_id="YP_001219667.1"
                     /db_xref="GI:148244973"
                     /db_xref="GeneID:5172213"
                     /translation="MEIFEFLFANEQIFTTITLILLIALFIGNIVVDKLKKYKDIDPN
                     GAVTLMDNNNLILLDVREERERKVGYIDGDIHIPLANVKSKLLSLDKHKKVLVYCRSG
                     SRSAHISGLLTRNKFVSVYNLKGGFQAWKRAKLPIKT"
     misc_feature    874915..875172
                     /locus_tag="COSY_0838"
                     /note="Rhodanese Homology Domain (RHOD); an alpha beta
                     fold domain found duplicated in the rhodanese protein. The
                     cysteine containing enzymatically active version of the
                     domain is also found in the Cdc25 class of protein
                     phosphatases and a variety of proteins...; Region: RHOD;
                     cd00158"
                     /db_xref="CDD:238089"
     misc_feature    875074..875076
                     /locus_tag="COSY_0838"
                     /note="active site residue [active]"
                     /db_xref="CDD:238089"
     gene            875206..875460
                     /gene="grxC"
                     /locus_tag="COSY_0839"
                     /db_xref="GeneID:5172198"
     CDS             875206..875460
                     /gene="grxC"
                     /locus_tag="COSY_0839"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="YP_001219668.1"
                     /db_xref="GI:148244974"
                     /db_xref="GeneID:5172198"
                     /translation="MKKNIIYCSDSCFFCQKAYQLLEKKGIHFKKHYVRTQVDWNEVK
                     EKTNRTTVPQIFINDFYIGGFDDLSAAEQSGKLDEILNKT"
     misc_feature    875218..875448
                     /gene="grxC"
                     /locus_tag="COSY_0839"
                     /note="Protein Disulfide Oxidoreductases and Other
                     Proteins with a Thioredoxin fold; Region:
                     Thioredoxin_like; cl00388"
                     /db_xref="CDD:241832"
     gene            875457..876440
                     /gene="gpsA"
                     /locus_tag="COSY_0840"
                     /db_xref="GeneID:5171867"
     CDS             875457..876440
                     /gene="gpsA"
                     /locus_tag="COSY_0840"
                     /EC_number="1.1.1.94"
                     /note="catalyzes the NAD(P)H-dependent reduction of
                     glycerol 3-phosphate to glycerone phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="YP_001219669.1"
                     /db_xref="GI:148244975"
                     /db_xref="GeneID:5171867"
                     /translation="MSNNLSIIGAGAWGSALSIALYDNFDTIYLHTHTQADIKKLKSK
                     HSALSIPYPYNVKIAYDLYKLQDSKNIIITTPSYAFSEILEKIKPFINHTHKIAWGTK
                     GFDTTKRCFLYESFKRLFPNRNGCVISGPSFAFEVALNKPTALVVASIDENTRNHFAK
                     LIQTNTLRTYTNADIIGVEVGGSVKNILAIAAGIASGLKYGFNTQAALIARGLSEMSR
                     LGKSLGAKNSTFIGLSGLGDLVLTCSDNLSRNRRFGQELVNNHNIKNALINVGGTVEG
                     LNTLDLILSIANKKQVEMPICEQVYQITQGKITPAEAVNYLMSREQQQNNE"
     misc_feature    875466..876416
                     /gene="gpsA"
                     /locus_tag="COSY_0840"
                     /note="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase; Validated; Region: gpsA; PRK00094"
                     /db_xref="CDD:234629"
     misc_feature    875475..875918
                     /gene="gpsA"
                     /locus_tag="COSY_0840"
                     /note="NAD-dependent glycerol-3-phosphate dehydrogenase
                     N-terminus; Region: NAD_Gly3P_dh_N; pfam01210"
                     /db_xref="CDD:201664"
     misc_feature    875976..876407
                     /gene="gpsA"
                     /locus_tag="COSY_0840"
                     /note="NAD-dependent glycerol-3-phosphate dehydrogenase
                     C-terminus; Region: NAD_Gly3P_dh_C; pfam07479"
                     /db_xref="CDD:116100"
     gene            876437..876964
                     /gene="cobC"
                     /locus_tag="COSY_0841"
                     /db_xref="GeneID:5171919"
     CDS             876437..876964
                     /gene="cobC"
                     /locus_tag="COSY_0841"
                     /EC_number="3.1.3.73"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ribazole phosphatase"
                     /protein_id="YP_001219670.1"
                     /db_xref="GI:148244976"
                     /db_xref="GeneID:5171919"
                     /translation="MKLDLLRHGIPIGGHIYRGNQNDPISKNGWQQMLKSTQGESWDY
                     IASSPLIRCAKFAKYLSKEQNIYCEIINNFKELGFGDWQGKNVDSIGLKLINNFRQDP
                     INHQPPNAENLYDFQSRVLSSFEDIRLHHTNKSVLIIAHAGVIRIIKSYLLNLPVEKM
                     FTIEVSCASSEHFTI"
     misc_feature    876440..876943
                     /gene="cobC"
                     /locus_tag="COSY_0841"
                     /note="Histidine phosphatase domain found in
                     phosphoglycerate mutases and related proteins, mostly
                     phosphatases; contains a His residue which is
                     phosphorylated during the reaction; Region: HP_PGM_like;
                     cd07067"
                     /db_xref="CDD:132718"
     misc_feature    order(876455..876460,876590..876592,876857..876862)
                     /gene="cobC"
                     /locus_tag="COSY_0841"
                     /note="catalytic core [active]"
                     /db_xref="CDD:132718"
     gene            complement(877363..877758)
                     /gene="rpsI"
                     /locus_tag="COSY_0842"
                     /db_xref="GeneID:5172129"
     CDS             complement(877363..877758)
                     /gene="rpsI"
                     /locus_tag="COSY_0842"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="YP_001219671.1"
                     /db_xref="GI:148244977"
                     /db_xref="GeneID:5172129"
                     /translation="MVKTEIYYATGRRKTSVARVYMSKGKGVFIVNKRPMNEYFGRET
                     SSMIINQPLDTSDMKDKFDFNIIVKGGGDTGQAGAIRLGVTRALIAYNNDLRGVLRKA
                     GFVTRDARIVERKKVGRKKARKSEQFSKR"
     misc_feature    complement(877366..877752)
                     /gene="rpsI"
                     /locus_tag="COSY_0842"
                     /note="30S ribosomal protein S9; Reviewed; Region: rpsI;
                     PRK00132"
                     /db_xref="CDD:178888"
     gene            complement(877771..878199)
                     /gene="rplM"
                     /locus_tag="COSY_0843"
                     /db_xref="GeneID:5172605"
     CDS             complement(877771..878199)
                     /gene="rplM"
                     /locus_tag="COSY_0843"
                     /note="in Escherichia coli this protein is one of the
                     earliest assembly proteins in the large subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="YP_001219672.1"
                     /db_xref="GI:148244978"
                     /db_xref="GeneID:5172605"
                     /translation="MKTFSAKARDVKRDWLLIDADGKTLGRLATKIASCLRGKHKPEY
                     TPHTDIGDYIVVINASKIKVTGNKFEDKIYYHHTGYVGNLKSIAFKDLQTKNPETIIN
                     KAVKGMLPKGPLGRDMFKKMKVFVDSEHTHGAQQPKVLDI"
     misc_feature    complement(877816..878157)
                     /gene="rplM"
                     /locus_tag="COSY_0843"
                     /note="Ribosomal protein L13.  Protein L13, a large
                     ribosomal subunit protein, is one of five proteins
                     required for an early folding intermediate of 23S rRNA in
                     the assembly of the large subunit. L13 is situated on the
                     bottom of the large subunit, near the...; Region:
                     Ribosomal_L13; cd00392"
                     /db_xref="CDD:238230"
     misc_feature    complement(order(877828..877833,877840..877842,
                     877852..877854,877858..877860,877864..877872,
                     877876..877884,877888..877896,877912..877917,
                     877999..878001,878005..878007,878089..878091,
                     878101..878103,878110..878112,878119..878124,
                     878128..878130))
                     /gene="rplM"
                     /locus_tag="COSY_0843"
                     /note="23S rRNA interface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238230"
     misc_feature    complement(877912..877914)
                     /gene="rplM"
                     /locus_tag="COSY_0843"
                     /note="L3 interface [polypeptide binding]; other site"
                     /db_xref="CDD:238230"
     gene            878434..880260
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /db_xref="GeneID:5172580"
     CDS             878434..880260
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DeaD"
                     /protein_id="YP_001219673.1"
                     /db_xref="GI:148244979"
                     /db_xref="GeneID:5172580"
                     /translation="MSENKSDQKSPSKFERLGLSNTILNVLDSIGYETPSPIQEQCIT
                     HLLNNKDIIGQAQTGTGKTAAFVLPLLDKINLNINAPQLLILAPTRELAIQVSEAVQT
                     YARGMKGFHVLPIYGGQSYDIQLRPLKRGVHAIVGTPGRVMDHIEKKTLKLDNLKSFV
                     LDEADEMLKMGFIDDIKWIMQRIPEQRQIALFSATMPNVIKKIAKQFLNQPKIIKIKT
                     KTETATTITQKYCMVGGLSNKLEALTRILEVTVFDAMIIFVRTKTLTTELTEKLSARG
                     FSADAINGDIQQNQRERIINDYKQGKIDILIATDIAARGLDVERISHVVNYDIPQDAE
                     SYVHRIGRTGRAGRKGEAILFVSNRERRMLNTIEHVTRQKITPIELPSVKIINAKRIE
                     TFKQNIIQTINNQNLEIFKKLVGEFQQENPKIEISQISSALAYIAQGNEPLLLSEKES
                     NLGFNQTPKEKIIISIRAKPLKGFPKIPMCRYKIEVGNNNNVKTSNILGAIANKTNMD
                     SEYIGSIQIFDHFSTIDLPAKISNEVFGVLQKTIVCGKHLNIVELTKKNNKDTIVGRT
                     EKRNLNRGKFSKNKNNNQRDNKNYHSKNKKYDKHSRKSKLSH"
     misc_feature    878440..879852
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /note="Superfamily II DNA and RNA helicases [DNA
                     replication, recombination, and repair / Transcription /
                     Translation, ribosomal structure and biogenesis]; Region:
                     SrmB; COG0513"
                     /db_xref="CDD:223587"
     misc_feature    878473..879066
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /note="DEAD-box helicases. A diverse family of proteins
                     involved in ATP-dependent RNA unwinding, needed in a
                     variety of cellular processes including splicing, ribosome
                     biogenesis and RNA degradation. The name derives from the
                     sequence of the Walker  B motif; Region: DEADc; cd00268"
                     /db_xref="CDD:238167"
     misc_feature    878608..878622
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238167"
     misc_feature    878917..878928
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /note="Mg++ binding site [ion binding]; other site"
                     /db_xref="CDD:238167"
     misc_feature    879010..879018
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /note="motif III; other site"
                     /db_xref="CDD:238167"
     misc_feature    879115..879498
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:238034"
     misc_feature    order(879211..879222,879280..879285,879358..879366)
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:238034"
     misc_feature    order(879382..879384,879445..879447,879457..879459,
                     879466..879468)
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238034"
     misc_feature    879874..880092
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /note="RNA recognition motif in Escherichia coli
                     cold-shock DEAD box protein A (CsdA) and similar proteins;
                     Region: RRM_EcCsdA_like; cd12499"
                     /db_xref="CDD:240943"
     misc_feature    order(879895..879897,879910..879921,879925..879933,
                     879937..879942,879958..879960,879967..879978,
                     880066..880071,880078..880080)
                     /gene="deaD"
                     /locus_tag="COSY_0844"
                     /note="putative RNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:240943"
     gene            880954..881157
                     /gene="cspC"
                     /locus_tag="COSY_0845"
                     /db_xref="GeneID:5172218"
     CDS             880954..881157
                     /gene="cspC"
                     /locus_tag="COSY_0845"
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein"
                     /protein_id="YP_001219674.1"
                     /db_xref="GI:148244980"
                     /db_xref="GeneID:5172218"
                     /translation="MSTTGKVKWFDAKKGFGFIEQESGGDVFVHFRAIQGDGYKSLEE
                     GQEVEFDLEDGEKGPQAVNVFPK"
     misc_feature    880963..881151
                     /gene="cspC"
                     /locus_tag="COSY_0845"
                     /note="Cold-Shock Protein (CSP) contains an S1-like
                     cold-shock domain (CSD) that is found in eukaryotes,
                     prokaryotes, and archaea.  CSP&apos;s include the major
                     cold-shock proteins CspA and CspB in bacteria and the
                     eukaryotic gene regulatory factor Y-box...; Region:
                     CSP_CDS; cd04458"
                     /db_xref="CDD:239905"
     misc_feature    order(880978..880980,881005..881007,881035..881037,
                     881122..881124)
                     /gene="cspC"
                     /locus_tag="COSY_0845"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:239905"
     misc_feature    order(880996..881016,881032..881043)
                     /gene="cspC"
                     /locus_tag="COSY_0845"
                     /note="RNA-binding motif; other site"
                     /db_xref="CDD:239905"
     gene            881948..883369
                     /gene="sbcB"
                     /locus_tag="COSY_0846"
                     /db_xref="GeneID:5172152"
     CDS             881948..883369
                     /gene="sbcB"
                     /locus_tag="COSY_0846"
                     /EC_number="3.1.11.1"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="YP_001219675.1"
                     /db_xref="GI:148244981"
                     /db_xref="GeneID:5172152"
                     /translation="MKTFYWYDYETFGISPKIDRISQFAGIRTDENFNILDEQMFYCK
                     PTNDCLLSPETCLITGISPQLCEQKGMIEHKFIKKIHAQLSTPDTCVIGYNSIRFDDE
                     FTRYALYRNFIDPYTWHWKNGNTRWDILDVVRLCYALKKDTSLKWVYDEQNKVIFKLD
                     QLSLANNIEHTYAHNALADVYATIAIAKIIKKTQPQLFNYAFSLRKKKTIKEKIKLFE
                     PMLHTSRVYSATLSCTRLSVALAYHSYHDRVFVFNLDQDPCILLELNIKTLKTLMFTK
                     NNQSALSKEMKGLQIKELIFNKSPMFVPNVYKLESKIIKQLKIDMSTCLQRLEFIKKN
                     QVIISKVVQDLYRNDQQRQPSSDVDQALYDDFINDNTDKHICNQIQTLSTNELKNFHP
                     KFKDNRLSKLLIHFKARNYPNILTENEKEEWFKTVQERVQTGKNGYTTIDDYLARINI
                     IRKQHPNQEKLWKQLETYSKSFF"
     misc_feature    881954..883351
                     /gene="sbcB"
                     /locus_tag="COSY_0846"
                     /note="exonuclease I; Provisional; Region: sbcB; PRK11779"
                     /db_xref="CDD:236979"
     misc_feature    881960..882490
                     /gene="sbcB"
                     /locus_tag="COSY_0846"
                     /note="N-terminal DEDDh 3&apos;-5&apos; exonuclease domain
                     of Escherichia coli exonuclease I and similar proteins;
                     Region: ExoI_N; cd06138"
                     /db_xref="CDD:99841"
     misc_feature    order(881969..881980,881984..881989,882119..882124,
                     882227..882232,882239..882247,882467..882469,
                     882482..882484)
                     /gene="sbcB"
                     /locus_tag="COSY_0846"
                     /note="active site"
                     /db_xref="CDD:99841"
     misc_feature    order(881969..881971,881975..881977,882245..882247,
                     882467..882469,882482..882484)
                     /gene="sbcB"
                     /locus_tag="COSY_0846"
                     /note="catalytic site [active]"
                     /db_xref="CDD:99841"
     misc_feature    order(881969..881980,881984..881986,882227..882232,
                     882239..882244,882467..882469,882482..882484)
                     /gene="sbcB"
                     /locus_tag="COSY_0846"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99841"
     misc_feature    882596..883363
                     /gene="sbcB"
                     /locus_tag="COSY_0846"
                     /note="Exonuclease C-terminal; Region: Exonuc_X-T_C;
                     pfam08411"
                     /db_xref="CDD:219829"
     gene            883439..884071
                     /gene="nth"
                     /locus_tag="COSY_0847"
                     /db_xref="GeneID:5171807"
     CDS             883439..884071
                     /gene="nth"
                     /locus_tag="COSY_0847"
                     /EC_number="4.2.99.18"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="YP_001219676.1"
                     /db_xref="GI:148244982"
                     /db_xref="GeneID:5171807"
                     /translation="MNAETRTKIFGRLLKKIPNPTTELNYSTPFELLVAVTLSAQATD
                     KSVNKVTDKLFPIANTPETISKLGEDTLRNTIRTIGLFNSKAKHIIQACKILIEKYNS
                     GVPKTRKELEALPGVGRKTANVVLNTAFGHPTIAVDTHIYRVANRTAIASGKTVLEVE
                     KKLVKFIPNEYRVPAHHLMILHGRYTCKARSPLCGECILLDLCEYEEKNL"
     misc_feature    883439..884068
                     /gene="nth"
                     /locus_tag="COSY_0847"
                     /note="Predicted EndoIII-related endonuclease [DNA
                     replication, recombination, and repair]; Region: Nth;
                     COG0177"
                     /db_xref="CDD:223255"
     misc_feature    883526..883987
                     /gene="nth"
                     /locus_tag="COSY_0847"
                     /note="endonuclease III; includes endonuclease III
                     (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA
                     glycosidases (Alka-family) and other DNA glycosidases;
                     Region: ENDO3c; cd00056"
                     /db_xref="CDD:238013"
     misc_feature    order(883559..883567,883574..883576,883691..883693)
                     /gene="nth"
                     /locus_tag="COSY_0847"
                     /note="minor groove reading motif; other site"
                     /db_xref="CDD:238013"
     misc_feature    883778..883801
                     /gene="nth"
                     /locus_tag="COSY_0847"
                     /note="helix-hairpin-helix signature motif; other site"
                     /db_xref="CDD:238013"
     misc_feature    order(883808..883810,883964..883966,883976..883978)
                     /gene="nth"
                     /locus_tag="COSY_0847"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238013"
     misc_feature    883850..883852
                     /gene="nth"
                     /locus_tag="COSY_0847"
                     /note="active site"
                     /db_xref="CDD:238013"
     misc_feature    883994..884053
                     /gene="nth"
                     /locus_tag="COSY_0847"
                     /note="iron-sulpphur binding domain in DNA-(apurinic or
                     apyrimidinic site) lyase (subfamily of ENDO3); Region:
                     FES; smart00525"
                     /db_xref="CDD:197771"
     gene            complement(884510..885127)
                     /gene="hisH"
                     /locus_tag="COSY_0848"
                     /db_xref="GeneID:5171956"
     CDS             complement(884510..885127)
                     /gene="hisH"
                     /locus_tag="COSY_0848"
                     /EC_number="2.4.2.-"
                     /note="with HisF IGPS catalyzes the conversion of
                     phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide
                     ribonucleotide phosphate and glutamine to
                     imidazole-glycerol phosphate,
                     5-aminoimidazol-4-carboxamide ribonucleotide, and
                     glutamate in histidine biosynthesis; the HisH subunit
                     provides the glutamine amidotransferase activity that
                     produces the ammonia necessary to HisF for the synthesis
                     of imidazole-glycerol phosphate and
                     5-aminoimidazol-4-carboxamide ribonucleotide"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="YP_001219677.1"
                     /db_xref="GI:148244983"
                     /db_xref="GeneID:5171956"
                     /translation="MQSIVIIDYGMGNTRSVQKALTYVAPNDNVVITNNADLIMQADR
                     IVFPGQGAIGACIEVLVKHKLINVIKHCVNEKPFLGICLGLQLLFDFSAENGGTDGLS
                     IVEGNIVKFSKNNLKVPHMGWNTVKQTIEHPLWHNIDDNTYFYSVHSYYVEQNSTNVV
                     AGLTSYGVDFTCAIAQNKLFAVQFHPEKSQYDGLQLLSNFVNWQN"
     misc_feature    complement(884516..885127)
                     /gene="hisH"
                     /locus_tag="COSY_0848"
                     /note="imidazole glycerol phosphate synthase subunit HisH;
                     Provisional; Region: hisH; PRK13146"
                     /db_xref="CDD:237290"
     misc_feature    complement(884525..885118)
                     /gene="hisH"
                     /locus_tag="COSY_0848"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in imidazole glycerol phosphate synthase (IGPS);
                     Region: GATase1_IGP_Synthase; cd01748"
                     /db_xref="CDD:153219"
     misc_feature    complement(order(884567..884569,884573..884575,
                     884876..884890,884975..884998))
                     /gene="hisH"
                     /locus_tag="COSY_0848"
                     /note="putative active site [active]"
                     /db_xref="CDD:153219"
     misc_feature    complement(884975..884998)
                     /gene="hisH"
                     /locus_tag="COSY_0848"
                     /note="oxyanion strand; other site"
                     /db_xref="CDD:153219"
     misc_feature    complement(order(884567..884569,884573..884575,
                     884882..884884))
                     /gene="hisH"
                     /locus_tag="COSY_0848"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153219"
     gene            complement(885134..885712)
                     /gene="hisB"
                     /locus_tag="COSY_0849"
                     /db_xref="GeneID:5172390"
     CDS             complement(885134..885712)
                     /gene="hisB"
                     /locus_tag="COSY_0849"
                     /EC_number="4.2.1.19"
                     /note="catalyzes the dehydration of
                     D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to
                     3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase"
                     /protein_id="YP_001219678.1"
                     /db_xref="GI:148244984"
                     /db_xref="GeneID:5172390"
                     /translation="MIKVSRKTNETDISVELNLYGMGKASIDTGVPFLDHMLDQVARH
                     GLMDLTIKCDGDIQIDDHHSVEDIGITLGQAFVQAVGDKKGLIRYGYSYVPLDESLSR
                     VVLDLSGRPSLKLNVSFTRAMIGTFDVDLISEFFQGFVNHALVTLHIDNLKGINSHHQ
                     AETIFKAFGRALRVAITEDERQEGIPSTKGSL"
     misc_feature    complement(885137..885706)
                     /gene="hisB"
                     /locus_tag="COSY_0849"
                     /note="Imidazoleglycerol-phosphate dehydratase; Region:
                     IGPD; cd07914"
                     /db_xref="CDD:153419"
     misc_feature    complement(order(885227..885229,885236..885241,
                     885311..885313,885383..885385,885422..885427,
                     885449..885451,885515..885517,885524..885529,
                     885581..885586,885593..885595,885605..885607,
                     885683..885685))
                     /gene="hisB"
                     /locus_tag="COSY_0849"
                     /note="putative active site pocket [active]"
                     /db_xref="CDD:153419"
     misc_feature    complement(order(885236..885250,885311..885316,
                     885323..885325,885329..885331,885338..885352,
                     885524..885529,885533..885541,885605..885607,
                     885614..885619))
                     /gene="hisB"
                     /locus_tag="COSY_0849"
                     /note="4-fold oligomerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:153419"
     misc_feature    complement(order(885227..885229,885236..885241,
                     885311..885313,885515..885517,885524..885529,
                     885605..885607))
                     /gene="hisB"
                     /locus_tag="COSY_0849"
                     /note="metal binding residues [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:153419"
     misc_feature    complement(order(885176..885178,885194..885196,
                     885203..885205,885257..885259,885263..885265,
                     885269..885271,885275..885277,885377..885379,
                     885383..885385,885395..885403,885413..885418,
                     885422..885430,885434..885442,885446..885448,
                     885452..885454))
                     /gene="hisB"
                     /locus_tag="COSY_0849"
                     /note="3-fold/trimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:153419"
     gene            complement(885727..885867)
                     /locus_tag="COSY_0850"
                     /db_xref="GeneID:5172177"
     CDS             complement(885727..885867)
                     /locus_tag="COSY_0850"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219679.1"
                     /db_xref="GI:148244985"
                     /db_xref="GeneID:5172177"
                     /translation="MFYASVIGILIMLVITGIISFITALALSLYFVEVIIFVNSYNKK
                     LF"
     gene            complement(885942..886964)
                     /gene="asd"
                     /locus_tag="COSY_0851"
                     /db_xref="GeneID:5172172"
     CDS             complement(885942..886964)
                     /gene="asd"
                     /locus_tag="COSY_0851"
                     /EC_number="1.2.1.11"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="YP_001219680.1"
                     /db_xref="GI:148244986"
                     /db_xref="GeneID:5172172"
                     /translation="MNKKYDVAVVGATGVVGEMILSILEQRNFQINSLYPLASANSTG
                     KKVFCQGKSWMVQDLNTFDFSQVQISLFSAGGSISKKYAPIAADSGCVVIDNTAYFRR
                     DKDIPLVIPEVNPHAIVDYTKRNIISNPNCSTIQMLVALKPIYDAVGIKRINVATYQA
                     VSGSGKEAITELTDQTVKLLNGQEIDIKVYPKQIAFNVIPHIDVFQDNGYTREEMKMV
                     WETQKIFEDENILVNPTAVRVPVIYGHSEAINIETRRKITATAATKILSEANGVTVMD
                     KREDGGYATPFVEATNHDDTFVGRIREDISHEKALNLWVVSDNIRKGAALNTVQIAEI
                     LIEEYL"
     misc_feature    complement(885957..886913)
                     /gene="asd"
                     /locus_tag="COSY_0851"
                     /note="aspartate-semialdehyde dehydrogenase; Provisional;
                     Region: PRK14874"
                     /db_xref="CDD:237845"
     misc_feature    complement(886602..886913)
                     /gene="asd"
                     /locus_tag="COSY_0851"
                     /note="Semialdehyde dehydrogenase, NAD binding domain;
                     Region: Semialdhyde_dh; smart00859"
                     /db_xref="CDD:214863"
     gene            complement(887570..888310)
                     /locus_tag="COSY_0852"
                     /db_xref="GeneID:5172256"
     CDS             complement(887570..888310)
                     /locus_tag="COSY_0852"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219681.1"
                     /db_xref="GI:148244987"
                     /db_xref="GeneID:5172256"
                     /translation="MIDNKTLSEYCHDYLDVDTFDDYCPNGLQIEGRQQIRKIIAGVS
                     VNQDLIERVIDEKADALFVHHGLFWQNESLVITGIKKNRIKILLEKNINLFAYHLPLD
                     AHLIVGNNIQLAMHLNIVNPTPIGDTLVWQGEVKLSLIEVSQLVQDITQRIPLVFGDL
                     NQQIKKIAWCTGDAQSYIKHAINIGADCFITGEISEQTPAIAKENNIAFISAGHYATE
                     RYGVQALCQHLSEKFNVQYQFIDIDNIV"
     misc_feature    complement(887579..888307)
                     /locus_tag="COSY_0852"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG0327"
                     /db_xref="CDD:223404"
     misc_feature    complement(887579..888301)
                     /locus_tag="COSY_0852"
                     /note="NIF3 (NGG1p interacting factor 3); Region: NIF3;
                     cl15371"
                     /db_xref="CDD:246938"
     gene            complement(888320..889384)
                     /gene="hisC"
                     /locus_tag="COSY_0853"
                     /db_xref="GeneID:5172166"
     CDS             complement(888320..889384)
                     /gene="hisC"
                     /locus_tag="COSY_0853"
                     /EC_number="2.6.1.9"
                     /note="catalyzes the formation of L-histidinol phosphate
                     from imidazole-acetol phosphate and glutamate in histidine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase"
                     /protein_id="YP_001219682.1"
                     /db_xref="GI:148244988"
                     /db_xref="GeneID:5172166"
                     /translation="MSFINSWLRSDIKMINAYHVPISADMVKMDAMESPFSLSDELTD
                     QYLTYLVDAQLNRYPSPSSDKLNQTLRLLMNIPKEFGVLLGNGSDELIQLLALACNTG
                     DTVLSVEPSFVMYGMITKFTRLNYQSVLLTDDFEIDDDTMQKAIKTYNPKLIFIAYPN
                     NPTGNMFNREIIEHIISSTKAMVVLDEAYYAYTTDSFLTDIAKYPNLVLLRTVSKIGF
                     AGLRLGLLIATQDTVNQLNKLRLPYNINILTQVSANFLLQEKNTINANVSVILAQRQV
                     LFDALVKINVLKVYPSQANFILFKAPNTNILFDFLKENGVLIKNLSVKKKLINCLRVT
                     IGTEEQNQKFINIVEKFYIL"
     misc_feature    complement(888329..889384)
                     /gene="hisC"
                     /locus_tag="COSY_0853"
                     /note="histidinol-phosphate aminotransferase; Provisional;
                     Region: PRK04870"
                     /db_xref="CDD:179888"
     misc_feature    complement(888335..889306)
                     /gene="hisC"
                     /locus_tag="COSY_0853"
                     /note="Aspartate aminotransferase family. This family
                     belongs to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). Pyridoxal phosphate
                     combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine...; Region: AAT_like;
                     cd00609"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(888719..888721,888740..888745,
                     888749..888751,888818..888820,888902..888904,
                     889049..889051,889118..889126))
                     /gene="hisC"
                     /locus_tag="COSY_0853"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(888632..888634,888638..888640,
                     888719..888727,888839..888841,889019..889021,
                     889115..889117))
                     /gene="hisC"
                     /locus_tag="COSY_0853"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99734"
     misc_feature    complement(888740..888742)
                     /gene="hisC"
                     /locus_tag="COSY_0853"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
     gene            complement(889381..890133)
                     /gene="thiD"
                     /locus_tag="COSY_0854"
                     /db_xref="GeneID:5172477"
     CDS             complement(889381..890133)
                     /gene="thiD"
                     /locus_tag="COSY_0854"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /note="bifunctional hydroxymethylpyrimidine /
                     phosphomethylpyrimidine kinase."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional thiamine biosynthesis ThiD"
                     /protein_id="YP_001219683.1"
                     /db_xref="GI:148244989"
                     /db_xref="GeneID:5172477"
                     /translation="MNNTVLVLSGLDPCGGAGLVADIESINQFGVTPLVIITNLTVQN
                     TASVENLVEVDCKFIIQQFECLQADVDFEVVKIGLLSSIQQIRTITKLVKNKIIVLDP
                     IVKSSSDFDFLDSVLIDSLKHQLLPMVKVITPNLTELQILADEQDEQKAIKKLSYNWI
                     LLTKTDSSDDVIEHCLYHYGTLIQSFSYQKLPGSYHGSGCTLSSAMSALIALGLDIEI
                     ASKRALDYTYQTLLNAKSIGKMQLHPNRQKPL"
     misc_feature    complement(889432..890124)
                     /gene="thiD"
                     /locus_tag="COSY_0854"
                     /note="4-amino-5-hydroxymethyl-2-methyl-pyrimidine
                     phosphate kinase (HMPP-kinase) catalyzes two consecutive
                     phosphorylation steps in the thiamine phosphate
                     biosynthesis pathway, leading to the synthesis of vitamin
                     B1. The first step is the phosphorylation of...; Region:
                     HMPP_kinase; cd01169"
                     /db_xref="CDD:238574"
     misc_feature    complement(order(889936..889941,889951..889953,
                     889960..889962,889969..889974,889978..889980,
                     889984..889989,890002..890016,890023..890025,
                     890029..890046,890053..890055,890062..890067,
                     890074..890076,890086..890088,890092..890097,
                     890101..890103,890122..890124))
                     /gene="thiD"
                     /locus_tag="COSY_0854"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238574"
     misc_feature    complement(order(889534..889536,889897..889899,
                     890005..890007,890068..890070,890104..890106))
                     /gene="thiD"
                     /locus_tag="COSY_0854"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238574"
     misc_feature    complement(order(889537..889539,889543..889545,
                     889645..889647,889720..889722,889831..889833))
                     /gene="thiD"
                     /locus_tag="COSY_0854"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238574"
     gene            complement(890126..890743)
                     /gene="dsbA"
                     /locus_tag="COSY_0855"
                     /db_xref="GeneID:5172694"
     CDS             complement(890126..890743)
                     /gene="dsbA"
                     /locus_tag="COSY_0855"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family thiol:disulfide interchange protein"
                     /protein_id="YP_001219684.1"
                     /db_xref="GI:148244990"
                     /db_xref="GeneID:5172694"
                     /translation="MKKILSILLIAFSSFVFSKDYEAGIDYIVLNKPVKTITGDKIEV
                     RELFWYYCLHCYNLEPLINRWLKTKPSNVEFVRQTAIFSERWLNGAIFYFVLEELDLV
                     EKLHEELFDVIHVNNKRFNSKESFVNWVASFGVNKNKIETAFNSFNVKIKVNRSKLNT
                     LKYKITGVPAIIINGKYLTDATYAGSHIDMFKVVDFLIKKESKLE"
     misc_feature    complement(890135..890677)
                     /gene="dsbA"
                     /locus_tag="COSY_0855"
                     /note="DsbA family, DsbA subfamily; DsbA is a monomeric
                     thiol disulfide oxidoreductase protein containing a redox
                     active CXXC motif imbedded in a TRX fold. It is involved
                     in the oxidative protein folding pathway in prokaryotes,
                     and is the strongest thiol...; Region: DsbA_DsbA; cd03019"
                     /db_xref="CDD:239317"
     misc_feature    complement(order(890237..890239,890579..890584,
                     890588..890590))
                     /gene="dsbA"
                     /locus_tag="COSY_0855"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239317"
     misc_feature    complement(890492..890500)
                     /gene="dsbA"
                     /locus_tag="COSY_0855"
                     /note="hinge region; other site"
                     /db_xref="CDD:239317"
     misc_feature    complement(order(890303..890332,890348..890374,
                     890384..890443,890456..890479))
                     /gene="dsbA"
                     /locus_tag="COSY_0855"
                     /note="alpha helical domain; other site"
                     /db_xref="CDD:239317"
     gene            complement(890746..891228)
                     /locus_tag="COSY_0856"
                     /db_xref="GeneID:5172296"
     CDS             complement(890746..891228)
                     /locus_tag="COSY_0856"
                     /EC_number="2.7.6.3"
                     /note="7,8-dihydro-6-hydroxymethylpterin-
                     pyrophosphokinase"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine pyrophosphokinase"
                     /protein_id="YP_001219685.1"
                     /db_xref="GI:148244991"
                     /db_xref="GeneID:5172296"
                     /translation="MANIHINIGSNRNRRENLSKAIYAIKVMFENTVFSKVYESRAFG
                     FKGDNFYNVGINATTNLIIAEVVNILHDIEENLGRDREASKFSSRSIDLDLTLYDSVI
                     DQNYNLPRDDILKYNFVLMPLAELNPNLVHPQQHQTYTQLRATMSGLKSYNIDILNTE
                     "
     misc_feature    complement(890851..891213)
                     /locus_tag="COSY_0856"
                     /note="7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
                     (HPPK). Folate derivatives are essential cofactors in the
                     biosynthesis of purines, pyrimidines, and amino acids as
                     well as formyl-tRNA. Mammalian cells are able to utilize
                     pre-formed folates after...; Region: HPPK; cd00483"
                     /db_xref="CDD:238269"
     misc_feature    complement(order(890875..890877,890881..890883,
                     890896..890901,890908..890910,890944..890949,
                     890953..890955,890962..890964,890971..890973,
                     890986..890988,890992..890994,891007..891009,
                     891016..891018,891028..891030,891073..891075,
                     891079..891081,891100..891102,891106..891111,
                     891202..891204))
                     /locus_tag="COSY_0856"
                     /note="catalytic center binding site [active]"
                     /db_xref="CDD:238269"
     misc_feature    complement(order(890881..890883,890896..890901,
                     890908..890910,890944..890949,890962..890964,
                     890986..890988,890992..890994,891007..891009,
                     891016..891018,891028..891030))
                     /locus_tag="COSY_0856"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238269"
     gene            complement(891221..891574)
                     /gene="folB"
                     /locus_tag="COSY_0857"
                     /db_xref="GeneID:5172160"
     CDS             complement(891221..891574)
                     /gene="folB"
                     /locus_tag="COSY_0857"
                     /EC_number="4.1.2.25"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="YP_001219686.1"
                     /db_xref="GI:148244992"
                     /db_xref="GeneID:5172160"
                     /translation="MDIIFIQGLKIDTVIGIYDWERKIRQDIVLDIEMSANIKAASKT
                     DHINQALDYKAVSKRLIDFVQRSEFQLVETLAERITQIVLKEFKVTWIKLTLNKGEVL
                     TGAQGVGIVIERSNG"
     misc_feature    complement(891233..891565)
                     /gene="folB"
                     /locus_tag="COSY_0857"
                     /note="Dihydroneopterin aldolase; Region: FolB;
                     smart00905"
                     /db_xref="CDD:214902"
     misc_feature    complement(order(891239..891241,891287..891289,
                     891491..891493,891497..891499))
                     /gene="folB"
                     /locus_tag="COSY_0857"
                     /note="active site"
                     /db_xref="CDD:238351"
     gene            891630..892220
                     /locus_tag="COSY_0858"
                     /db_xref="GeneID:5172006"
     CDS             891630..892220
                     /locus_tag="COSY_0858"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219687.1"
                     /db_xref="GI:148244993"
                     /db_xref="GeneID:5172006"
                     /translation="MLPELFFTIIILSYLIGSISTAIIICKILNLPDPRTQGSNNPGA
                     TNILRIGGKKAAIITLVGDGLKGMIPVLIAHYLDLDTLNITWIIFAAFLGHVYPIFFS
                     FKGGKGVATFLGALLALSYPTGLSFIITWIFVAKVLKISSLSALVATALTPVYFYLIT
                     NNLIATYVIISICIWIFYTHQSNIKRLFNNQENKIN"
     misc_feature    891690..892214
                     /locus_tag="COSY_0858"
                     /note="putative glycerol-3-phosphate acyltransferase PlsY;
                     Provisional; Region: PRK00220"
                     /db_xref="CDD:234691"
     gene            892320..893231
                     /gene="ppk"
                     /locus_tag="COSY_0859"
                     /db_xref="GeneID:5172155"
     CDS             892320..893231
                     /gene="ppk"
                     /locus_tag="COSY_0859"
                     /EC_number="2.7.4.1"
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase"
                     /protein_id="YP_001219688.1"
                     /db_xref="GI:148244994"
                     /db_xref="GeneID:5172155"
                     /translation="MLIRKKFSKKDAKNKIKKLQNNKYVMHKNNVMSGNALLSLSEIA
                     GDYPYAKKMHVEEYENEKYLLQTELLKAQDWIKNYNKKIILLFEGRDAAGKGGTIKRF
                     MEHLNPRAARVIALEKPSRVELGQWYFQRYIKHFPTNGEMVLFDRSWYNRAGVERVMG
                     FCKNSEYLEFMRQAPLLERMLVNDGFMLSKYWFSVSHQEQLRRFHLRKNDPLKRWKLS
                     EIDLQSLTKWEQYTKARKDMFFYTNTADSSWIVVKSDDKKRARINCIRHFLYYLNYPN
                     KDTKIVFKPDSKIIGSVSNLYKNKEDI"
     misc_feature    892473..893159
                     /gene="ppk"
                     /locus_tag="COSY_0859"
                     /note="polyphosphate kinase 2, PA0141 family; Region:
                     PPK2_P_aer; TIGR03707"
                     /db_xref="CDD:213852"
     gene            893228..893482
                     /locus_tag="COSY_0860"
                     /db_xref="GeneID:5171815"
     CDS             893228..893482
                     /locus_tag="COSY_0860"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219689.1"
                     /db_xref="GI:148244995"
                     /db_xref="GeneID:5171815"
                     /translation="MISNKKQQLKDAIQIARKAEIEALIATEKAQKSVNKIVKLRKEL
                     DVQYKKLAKKIKENKKNNDKKIEYFSKKKVKKAKKKKSLK"
     gene            complement(893582..894340)
                     /locus_tag="COSY_0861"
                     /db_xref="GeneID:5172150"
     CDS             complement(893582..894340)
                     /locus_tag="COSY_0861"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="YP_001219690.1"
                     /db_xref="GI:148244996"
                     /db_xref="GeneID:5172150"
                     /translation="MWISYKTIVIKEILRFSRIWVQTIFPPIITTSLYLLIFGGLMGK
                     RIGDMQGVDYLHYIIPGVILMTVITNSYTNTVTSFFLAKFNHSIEELLVAPVSYWVIL
                     LGYVSGGVSRGFAVGLGVSIAMSFFIDFEINNMLIVLIIFLFTSILFSLAGFINAIFA
                     QSFDDISIVPTFVLMPMTYLGGIFYNVEILPQFWQNISKFNPIYYMVDSFRLGFLGVS
                     TSEFWVSILVLLSIIIVLAIFAFCLLKRNVNIKT"
     misc_feature    complement(893585..894340)
                     /locus_tag="COSY_0861"
                     /note="inner membrane transport permease; Provisional;
                     Region: PRK15066"
                     /db_xref="CDD:237896"
     misc_feature    complement(893681..894313)
                     /locus_tag="COSY_0861"
                     /note="ABC-type multidrug transport system, permease
                     component [Defense mechanisms]; Region: COG0842"
                     /db_xref="CDD:223912"
     gene            complement(894340..895257)
                     /locus_tag="COSY_0862"
                     /db_xref="GeneID:5172145"
     CDS             complement(894340..895257)
                     /locus_tag="COSY_0862"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="YP_001219691.1"
                     /db_xref="GI:148244997"
                     /db_xref="GeneID:5172145"
                     /translation="MSTALLIKGLKKTYSNQLEALKGIDLCVDHGDFYALLGSNGAGK
                     TTVIGIICGLLNKTSGSIKVLGFNQSNHVNQVKKLIGLMPQEFNFNPFEPIEEILINQ
                     AGYYGIAKSKAKIQAEFLLKEVDLWEKRSDMAKSLSGGMKRRLMLARALIHQPKILIL
                     DEPTAGVDVKIRHSIWRFLSKLNRQGMTIILTTHYLGEAELLCRNVAILNEGKVIKQT
                     SMKALLSQVDQQVLILESLSQLPQTITSDRFKCERLDDHSLQVVLNSDISITSVLHDL
                     DTQGVSVDYVHSAQNRLETLFLYLTNKEE"
     misc_feature    complement(894349..895257)
                     /locus_tag="COSY_0862"
                     /note="ABC-type multidrug transport system, ATPase
                     component [Defense mechanisms]; Region: CcmA; COG1131"
                     /db_xref="CDD:224054"
     misc_feature    complement(894601..895239)
                     /locus_tag="COSY_0862"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    complement(895123..895146)
                     /locus_tag="COSY_0862"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(894676..894678,894772..894777,
                     895003..895005,895120..895128,895132..895137))
                     /locus_tag="COSY_0862"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(895003..895014)
                     /locus_tag="COSY_0862"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(894820..894849)
                     /locus_tag="COSY_0862"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(894772..894789)
                     /locus_tag="COSY_0862"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(894754..894765)
                     /locus_tag="COSY_0862"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(894670..894690)
                     /locus_tag="COSY_0862"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            895365..896888
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /db_xref="GeneID:5172139"
     CDS             895365..896888
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /EC_number="2.3.1.12"
                     /note="dihydrolipoamide acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex E2 component"
                     /protein_id="YP_001219692.1"
                     /db_xref="GI:148244998"
                     /db_xref="GeneID:5172139"
                     /translation="MMNIKNIVLPDIGDFYEVKIIEILVNVGDKINTNDSIVTLEKDK
                     SSMKIPSPYTGIITKIEVNIGNKIKQNDIILSIESEYSEIQNTNKNIKNEYQKTEIIP
                     VVVPNIGDFDEIEVIEILVSVGDELSVEDSIITLESDKASMEIPTPVAGKVININVAL
                     GDKISLGTLILNIKSIAEETPTEIKIQSSTPIPIPPNPSTLTPITNNINQIVSEPIRG
                     NSHASPSIRKLARELGVNLSYITGTGRKGRILDTDLKSHVKQIITSNNFNSVLPKPPI
                     IDFSKFGNTETIKLSRINKLSGKHLTTCWLSIPHVTQFDEVNINQMEAYRQEQKANGI
                     KLTPLVFIMKALVRTLKNHLRFNASLDESGENLIIKKYFNLGIAMDTPKGLIVPVIRD
                     VEKKSLTDLAKELFETSKNARENKLKPADMQGSGLTISSLGGIGGTQFTPIVNAPEVA
                     ILGISRSYFKPTWDGENFIPTLTLPLALSYDHRVIDGAQGGRFMAELNTTLREANYD"
     misc_feature    895374..896867
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /note="dihydrolipoamide acetyltransferase; Reviewed;
                     Region: PRK11855"
                     /db_xref="CDD:237000"
     misc_feature    895377..895580
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /note="Lipoyl domain of the dihydrolipoyl acyltransferase
                     component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
                     dehydrogenase multienzyme complexes, like pyruvate
                     dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
                     and branched-chain 2-oxo acid...; Region: lipoyl_domain;
                     cd06849"
                     /db_xref="CDD:133458"
     misc_feature    order(895464..895466,895485..895502,895512..895514)
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /note="E3 interaction surface; other site"
                     /db_xref="CDD:133458"
     misc_feature    895494..895496
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /note="lipoyl attachment site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133458"
     misc_feature    895665..895883
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /note="Lipoyl domain of the dihydrolipoyl acyltransferase
                     component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
                     dehydrogenase multienzyme complexes, like pyruvate
                     dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
                     and branched-chain 2-oxo acid...; Region: lipoyl_domain;
                     cd06849"
                     /db_xref="CDD:133458"
     misc_feature    order(895752..895754,895773..895790,895800..895802)
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /note="E3 interaction surface; other site"
                     /db_xref="CDD:133458"
     misc_feature    895782..895784
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /note="lipoyl attachment site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133458"
     misc_feature    896016..896132
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /note="e3 binding domain; Region: E3_binding; pfam02817"
                     /db_xref="CDD:202412"
     misc_feature    896265..896867
                     /gene="aceF"
                     /locus_tag="COSY_0863"
                     /note="2-oxoacid dehydrogenases acyltransferase (catalytic
                     domain); Region: 2-oxoacid_dh; pfam00198"
                     /db_xref="CDD:215782"
     gene            896881..898287
                     /gene="lpdA"
                     /locus_tag="COSY_0864"
                     /db_xref="GeneID:5172426"
     CDS             896881..898287
                     /gene="lpdA"
                     /locus_tag="COSY_0864"
                     /EC_number="1.8.1.4"
                     /note="dihydrolipoamide dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex E3 component"
                     /protein_id="YP_001219693.1"
                     /db_xref="GI:148244999"
                     /db_xref="GeneID:5172426"
                     /translation="MIKTQIVIIGSGPGGYTAAFRLADLGKQVTLIERYNALGGVCLN
                     VGCIPSKALLHTAQIINEAKDASHVGVTFNEPLISINGIRTNKDNIVTKLTNGIKTLA
                     KARKINVITGYGRFISANQITIENSDDIIEFEQCIIATGSQVTKIPTLPFDDARVMSS
                     TDALNLSNIPKRLLVVGGGIIGLEMATVYNALGSEITVVELSDQLITSADKDIINPLL
                     RRIKKQYANIFLNTKITKIEALKEGIKVRFEGKNTPKFDTFDKILVAIGRTPNGRLID
                     CEKAGVEINDWGFIPVNKQMKTNVNNIYAIGDIIGQPMLAHKAIHEAKIAAEVICGYK
                     SGFNALTIPSIAYTDPEIAWTGKTEKELKAEGISYEKGLFPWTNSGRSLSIGRSEGIT
                     KGLFDTKIGKILGMGICGTNASELIAEATLAIEMGCDMDDIALTIHAHPTLSETTAFA
                     TEMAQGTITDLLSSKKKK"
     misc_feature    896884..898281
                     /gene="lpdA"
                     /locus_tag="COSY_0864"
                     /note="dihydrolipoamide dehydrogenase; Reviewed; Region:
                     PRK06467"
                     /db_xref="CDD:180579"
     misc_feature    896902..>897006
                     /gene="lpdA"
                     /locus_tag="COSY_0864"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; pfam13450"
                     /db_xref="CDD:205628"
     misc_feature    897430..897636
                     /gene="lpdA"
                     /locus_tag="COSY_0864"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:215691"
     misc_feature    897904..898215
                     /gene="lpdA"
                     /locus_tag="COSY_0864"
                     /note="Pyridine nucleotide-disulphide oxidoreductase,
                     dimerisation domain; Region: Pyr_redox_dim; pfam02852"
                     /db_xref="CDD:217252"
     gene            898299..898952
                     /gene="pcm"
                     /locus_tag="COSY_0865"
                     /db_xref="GeneID:5172283"
     CDS             898299..898952
                     /gene="pcm"
                     /locus_tag="COSY_0865"
                     /EC_number="2.1.1.77"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase"
                     /protein_id="YP_001219694.1"
                     /db_xref="GI:148245000"
                     /db_xref="GeneID:5172283"
                     /translation="MNIKQARKNVIEQQIRPWGGLNYIANNALKDTPREDFVPEKYKN
                     LTFADIEIPLTSKAKMLFPKIEGRLLNALNIKKHETVLEIGTGSGYLTAVLSKLCKSV
                     TSIEIDENLSHNAKKRIDTLGIDNVTLEVVDASKNWKYNDFFNVVIISSSVPKITGYY
                     FHLLNIGGRIFVIEGTKNIMSAKLITRISKNKWDTKSLFETQLDAMRGLESSNNFEF"
     misc_feature    898314..898901
                     /gene="pcm"
                     /locus_tag="COSY_0865"
                     /note="Protein-L-isoaspartate carboxylmethyltransferase
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: Pcm; COG2518"
                     /db_xref="CDD:225316"
     misc_feature    898536..898817
                     /gene="pcm"
                     /locus_tag="COSY_0865"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(898548..898568,898614..898619,898692..898700,
                     898731..898733)
                     /gene="pcm"
                     /locus_tag="COSY_0865"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            898955..901336
                     /locus_tag="COSY_0866"
                     /db_xref="GeneID:5171879"
     CDS             898955..901336
                     /locus_tag="COSY_0866"
                     /note="exporters of resistance-nodulation-cell division
                     (RND) superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219695.1"
                     /db_xref="GI:148245001"
                     /db_xref="GeneID:5171879"
                     /translation="MNLFFDFILKKASLGLTLLLLIAIFFIAQISDFQLDASADSLVL
                     EGDENLRYYQNIKKNYGSDDYLIISYQVKDSLITPKQLDHLRKFKQDLTKINQIRSVT
                     TILDVPLFRSPPLSLAELASENISIDNDNANLALANNEFKNSPLYANNLVSKDGKTTA
                     ILVKLKNNQKFKELRENLDKMRTQRANNKLSNDQQLKLKIIEKQVLKNITTQNKIQAQ
                     TIAQIRTTINQYSNKAHLFLGGLPMITTDIVTYISNDLIIFSLAVIGLMSLILTIIFK
                     SVRWVIIPIGISIFSSFIMTGILAYLGWKITVISSNFFSLLLVMTLSIVIHLIVRYRE
                     ISQLNPNINSHQLIKDTLSQMFKPCFFTTLTTFVAFSSLLISGIRPVINFGWIMSIGV
                     IIALVLSFLAFPMIMSLLPKAKITKQKTELRATTLLAKFVEKFGNHLLVILVILLIGS
                     GFGISKLSVENRFINYFKQNTEINQGLTLIDKELGGTIPLEIIFDNLAEDYWFDEDLR
                     NEIHDVHQYLNSLDETGKVLSIDTLMQILTQANDGKTPNGFLLNIIHSQLPERAKVQV
                     LYPYLSENSGQLRMVIRIRETEKELKRGKLIDQIQHHISTELGFKQNSFHLSGMLILY
                     NNMLQSLFDSQIKTITVVFVMIFIMFLFIFKSISLSIIALIPNTLPSLFILGIMGLLN
                     IPLDLMTITISTIAIGIGVDNAIHYIHRFQHEFRKDNDYIATMYRSHTSIGLAMFYTS
                     ITVTIGFLILALSNFIPSIYFGVFTAIAMLSALLANLTLLPKLILMIKPKINI"
     misc_feature    899057..901255
                     /locus_tag="COSY_0866"
                     /note="Predicted exporters of the RND superfamily [General
                     function prediction only]; Region: COG1033"
                     /db_xref="CDD:223964"
     misc_feature    <899849..900154
                     /locus_tag="COSY_0866"
                     /note="Protein export membrane protein; Region: SecD_SecF;
                     cl14618"
                     /db_xref="CDD:246677"
     gene            901396..902967
                     /gene="nadB"
                     /locus_tag="COSY_0867"
                     /db_xref="GeneID:5172130"
     CDS             901396..902967
                     /gene="nadB"
                     /locus_tag="COSY_0867"
                     /EC_number="1.4.3.16"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="YP_001219696.1"
                     /db_xref="GI:148245002"
                     /db_xref="GeneID:5172130"
                     /translation="MTKQHHFDVLIIGTGSAGLMSALQLSDNLSIALIAKDKILEGSS
                     YYAQGGISAVLDINDNFTTHIQDTLLTAAGLGDETAIRFMVENAPKAITSLEHSGVKF
                     TKNKDKEDYHLTTEGGHSHRRVAHVADKTGQSIQTNLLKNVKEKSNITLFENYIAIDL
                     LIKSYDCYGAYVLNKNTNQVESFISHKTIIATGGASKTYLYTSNPDTSTGDGIAMAYR
                     AKCIITNMEFTQFHPTCLYHPHAKSFLITEALRGEGGKLILQNGEAFMHKFDNREELA
                     PRDIVARAIDVQIKTHGFECVYLDISFKNKSWIKQHFPTIYKKCKSLGIDISKNAIPV
                     VPAAHYTCGGVQTNLDGQTNIDNLYAIGEVAHTGVHGANRMASNSLLECVVFAKSCAN
                     YINQQSTTLTLTYKQFSQWDASKAAPSKEKVVVSHLWDEIRRIMWNFVGIVRSNKRLK
                     YAQYRLNQIQAEVNDYYKLYLISSNLIELRNLIQTAQLIVQSAIFRTESRGLHYNEDH
                     PQQSNHPINTIIKKS"
     misc_feature    901396..902958
                     /gene="nadB"
                     /locus_tag="COSY_0867"
                     /note="L-aspartate oxidase; Provisional; Region: PRK09077"
                     /db_xref="CDD:236374"
     misc_feature    901417..902580
                     /gene="nadB"
                     /locus_tag="COSY_0867"
                     /note="L-aspartate oxidase; Provisional; Region: PRK06175"
                     /db_xref="CDD:180442"
     misc_feature    902680..>902925
                     /gene="nadB"
                     /locus_tag="COSY_0867"
                     /note="Fumarate reductase flavoprotein C-term; Region:
                     Succ_DH_flav_C; pfam02910"
                     /db_xref="CDD:217281"
     gene            902964..903506
                     /gene="def"
                     /locus_tag="COSY_0868"
                     /db_xref="GeneID:5172012"
     CDS             902964..903506
                     /gene="def"
                     /locus_tag="COSY_0868"
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /transl_table=11
                     /product="polypeptide deformylase"
                     /protein_id="YP_001219697.1"
                     /db_xref="GI:148245003"
                     /db_xref="GeneID:5172012"
                     /translation="MILPILSYPDKRLRIKAKNVNIVNKTIQTLIKNMFETMYARNGI
                     GLAATQVNQHLQIVVIDVPNSQFLFKNRKNNSQKLLQKQHPLCFINPEIKEKYGQEKH
                     TEGCLSVSDFQAEIQRANHIKVKALNEKGEIFILQATGLLAICIQHEIDHLKGILFVD
                     YLSKLKQKRLLERIKKMTKV"
     misc_feature    902976..903437
                     /gene="def"
                     /locus_tag="COSY_0868"
                     /note="Polypeptide or peptide deformylase; a family of
                     metalloenzymes that catalyzes the removal of the
                     N-terminal formyl group in a growing polypeptide chain
                     following translation initiation during protein synthesis
                     in prokaryotes. These enzymes utilize Fe(II)...; Region:
                     Pep_deformylase; cd00487"
                     /db_xref="CDD:238271"
     misc_feature    order(903090..903098,903111..903113,903276..903284,
                     903405..903410,903417..903419)
                     /gene="def"
                     /locus_tag="COSY_0868"
                     /note="active site"
                     /db_xref="CDD:238271"
     misc_feature    order(903096..903098,903111..903113,903282..903284,
                     903408..903410)
                     /gene="def"
                     /locus_tag="COSY_0868"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:238271"
     misc_feature    order(903279..903281,903405..903407,903417..903419)
                     /gene="def"
                     /locus_tag="COSY_0868"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:238271"
     gene            904190..905731
                     /gene="purH"
                     /locus_tag="COSY_0869"
                     /db_xref="GeneID:5172221"
     CDS             904190..905731
                     /gene="purH"
                     /locus_tag="COSY_0869"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /note="involved in de novo purine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="YP_001219698.1"
                     /db_xref="GI:148245004"
                     /db_xref="GeneID:5172221"
                     /translation="MSIQRALISVSNKNGVIDFAQFLVDNNIDIISTDGTAKLLIENN
                     IPVIEVSDYTRFPEIMAGRVKTLNPKIHGGILARRGIDEDIMAQNNIKPIDLVIVNLY
                     PFQATIAKTDCTLEDAIENIDIGGSAMLRSSAKNYTSVTVIVNNTDYQKVMDEISELG
                     NTTLETRAMLALKTFEHTAMYDGAIANYLGKNKNGFSNTINLQFNKAQSIRYGENPHQ
                     KAAFYVESNLSESCLASSIQCQGKEMSYNNMADADAALECVRSFNKPCCVIVKHANPC
                     GIAIRNNINNAYLDAFKTDPTSAFGGIIAFNRVLDKNTAQNIIDKQFVEVIIAPSVQT
                     QAKQILSTKQNIRVLECGNLNTAKPSLDYRRVTGGLLVQDKDLGIITEDDIKCVSDLT
                     PTKDQIEDLLFAWKVAKVVKSNAIVYAKNKMTIGIGAGQMSRVYSARIAGMKATDADF
                     IIDSCVMASDAFFPFRDGIDSVAQAGIKAIIQPGGSIRDKQVIKAANEHGITMVFTGM
                     RHFKH"
     misc_feature    904190..905728
                     /gene="purH"
                     /locus_tag="COSY_0869"
                     /note="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase; Provisional; Region:
                     purH; PRK00881"
                     /db_xref="CDD:234854"
     misc_feature    904199..904756
                     /gene="purH"
                     /locus_tag="COSY_0869"
                     /note="Inosine monophosphate cyclohydrolase domain. This
                     is the N-terminal domain in the purine biosynthesis
                     pathway protein ATIC (purH). The bifunctional ATIC protein
                     contains a C-terminal  ATIC formylase domain that
                     formylates...; Region: IMPCH; cd01421"
                     /db_xref="CDD:238709"
     misc_feature    order(904220..904222,904226..904228,904286..904288,
                     904295..904297,904382..904387,904487..904489,
                     904556..904558)
                     /gene="purH"
                     /locus_tag="COSY_0869"
                     /note="purine monophosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238709"
     misc_feature    order(904355..904357,904364..904369,904376..904381,
                     904388..904396,904403..904408,904415..904417,
                     904553..904561,904568..904570,904580..904585,
                     904592..904594,904691..904693,904700..904708,
                     904730..904738,904742..904747,904754..904756)
                     /gene="purH"
                     /locus_tag="COSY_0869"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238709"
     misc_feature    order(904382..904384,904556..904558)
                     /gene="purH"
                     /locus_tag="COSY_0869"
                     /note="putative catalytic residues [active]"
                     /db_xref="CDD:238709"
     misc_feature    904586..905524
                     /gene="purH"
                     /locus_tag="COSY_0869"
                     /note="AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas;
                     smart00798"
                     /db_xref="CDD:214822"
     gene            complement(906146..907534)
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /db_xref="GeneID:5172138"
     CDS             complement(906146..907534)
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
                     /protein_id="YP_001219699.1"
                     /db_xref="GI:148245005"
                     /db_xref="GeneID:5172138"
                     /translation="MNATDFSSLKLHPNLLKNLTILGYDLMTPIQKLSLPVILSGKDV
                     IGQGKTGSGKTVAFGLGLLQKLDVKLFKLQSIVLCPTRELANQVAVEIQKLARVINNI
                     KVVVLCGGMSFGLQIDSLRHGVHVVVGTPGRIEEHLRKGTLKLSYINTLVLDEADRML
                     DMGFQESVDNIIETMPTNRQTLLFSATCLDTITNITQRVMRSPIMVKVPLINERSTIK
                     QYFYKINTDNERMMALRLLLAKYKPESSLVFCNTKRDAQKVANELVYYGFYALAIHGD
                     LDQRERDQALIRFSNKSVSILVATDVAARGLDIDSLDMVINFDIAHDDQVHIHRIGRT
                     GRAGHFGIACTLYSNRETYKLDTLKLGTGDDIILDSLPSKHYLNNPIKKPSMITLKID
                     GGKKHKLRPGDIVGGLTGKKKEITFNQIGKINVLSQWSYVAVNSNFVKTALKKIRYDK
                     LKGRSFKVRILS"
     misc_feature    complement(906152..907534)
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /note="ATP-dependent RNA helicase DbpA; Provisional;
                     Region: PRK11776"
                     /db_xref="CDD:236977"
     misc_feature    complement(906914..907519)
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /note="DEAD-box helicases. A diverse family of proteins
                     involved in ATP-dependent RNA unwinding, needed in a
                     variety of cellular processes including splicing, ribosome
                     biogenesis and RNA degradation. The name derives from the
                     sequence of the Walker  B motif; Region: DEADc; cd00268"
                     /db_xref="CDD:238167"
     misc_feature    complement(907370..907384)
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238167"
     misc_feature    complement(907064..907075)
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /note="Mg++ binding site [ion binding]; other site"
                     /db_xref="CDD:238167"
     misc_feature    complement(906974..906982)
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /note="motif III; other site"
                     /db_xref="CDD:238167"
     misc_feature    complement(906506..906886)
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:238034"
     misc_feature    complement(order(906629..906637,906710..906715,
                     906773..906784))
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:238034"
     misc_feature    complement(order(906527..906529,906536..906538,
                     906548..906550,906611..906613))
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238034"
     misc_feature    complement(906152..906373)
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /note="RNA recognition motif in Escherichia coli RNA
                     helicase dbpA and similar proteins; Region:
                     RRM_EcDbpA_like; cd12501"
                     /db_xref="CDD:240945"
     misc_feature    complement(order(906164..906166,906173..906178,
                     906266..906277,906284..906286,906305..906310,
                     906314..906322,906326..906337,906350..906352))
                     /gene="dbpA"
                     /locus_tag="COSY_0870"
                     /note="putative RNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:240945"
     gene            907791..908348
                     /locus_tag="COSY_0871"
                     /db_xref="GeneID:5172214"
     CDS             907791..908348
                     /locus_tag="COSY_0871"
                     /EC_number="6.3.3.2"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="YP_001219700.1"
                     /db_xref="GI:148245006"
                     /db_xref="GeneID:5172214"
                     /translation="MKALRLTLRQKRHTINHNNRKKFAQFLLFQTQKLTTFKREEKIA
                     IYLPNDGEIDTKYIANFLKRQNFSIYLPKLIGKKLKFAKVNKFFKKNIFGIKEPIYTK
                     ILNTKQMNIIFVPLVGFDKNKNRIGMGSGFYDHTLAFKKYQQNYKNPKLYGLAFDCQK
                     VDKLNTKPWDVPLDAIITPTKIYNK"
     misc_feature    907794..908339
                     /locus_tag="COSY_0871"
                     /note="5-formyltetrahydrofolate cyclo-ligase [Coenzyme
                     metabolism]; Region: COG0212"
                     /db_xref="CDD:223290"
     misc_feature    907794..908327
                     /locus_tag="COSY_0871"
                     /note="5-formyltetrahydrofolate cyclo-ligase family;
                     Region: 5-FTHF_cyc-lig; pfam01812"
                     /db_xref="CDD:216717"
     gene            complement(908710..909891)
                     /locus_tag="COSY_0872"
                     /db_xref="GeneID:5172123"
     CDS             complement(908710..909891)
                     /locus_tag="COSY_0872"
                     /EC_number="1.14.13.-"
                     /note="2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol
                     hydroxylase (EC:1.14.13.-) UbiF VisC"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiH/COQ6 monooxygenase family protein"
                     /protein_id="YP_001219701.1"
                     /db_xref="GI:148245007"
                     /db_xref="GeneID:5172123"
                     /translation="MSSENNLQYDIVIIGGGMVGQAFALSMINKGLKIVIIEPNYFNP
                     KLQDKYHTRVSAITSKSETLLRNIGVWRLIKRKYAFTDIHIWDQNSHGSLDFHSQDED
                     INQLGYIIENDAIQSAMYTILEKTRVEFICTELTAINRIDNGYQVDLNSNHKIKCGLL
                     VGADGAKSNVRELAGIEFSENNYQQRAIVCNIESLQSFQNTIWQRFLSDSIIALLPLS
                     DKQASIVWSAENNLADELIQLSVKQFADRLSKSVEYKFSRFKVVSDIKSFTLIERSAQ
                     DYIKRNLVLIGDAAHNIHPLGGQGVNLGFSDVIELSQQIQANHKSLDDYLVLKKYARS
                     RRLNNELMAKTMTGLNWIYKENNEPLRWLRGFGMNLINESKTLKSYFQKQASGNKLFN
                     I"
     misc_feature    complement(908731..909870)
                     /locus_tag="COSY_0872"
                     /note="ubiquinone biosynthesis hydroxylase family protein;
                     Provisional; Region: PRK07608; cl17314"
                     /db_xref="CDD:247868"
     misc_feature    complement(908731..909864)
                     /locus_tag="COSY_0872"
                     /note="Ubiquinone biosynthesis hydroxylase,
                     UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988"
                     /db_xref="CDD:233671"
     gene            complement(909891..911210)
                     /gene="pmbA"
                     /locus_tag="COSY_0873"
                     /db_xref="GeneID:5172119"
     CDS             complement(909891..911210)
                     /gene="pmbA"
                     /locus_tag="COSY_0873"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation protein PmbA"
                     /protein_id="YP_001219702.1"
                     /db_xref="GI:148245008"
                     /db_xref="GeneID:5172119"
                     /translation="MSFSLENTAQFAIDFLKKYDITDYEIFLSSSSGVSTAVRLGKIE
                     TLEHHLDKMFDINVYMGNKKGHASSVDLNKQGIAKTIESACLIAKYTQEDLFNGLAPK
                     ELMAFNPPDLDLYYPWDLDPSHSVDLAKRCETAALEQKYIDSSDGAELSSFQGKDLYI
                     NSHGMMAAQQGAKHSLHCSIIAKQDRDMQTAYEYTVALDNFDLESPEVVGKKAANLAV
                     NKLASRSLESRKCPVIFTSRLSGGLFSQLMGALNGARQYKKSTFLLDSVDQLVMPSSI
                     SLLEKPLVKKTIGSKAFDQDGVLKKQQYFVKNGQVQSYIMGQYSANQLGLKTTANAGG
                     VNNVMIEHKFEGGLDEVIKNMHQGLVVTELMGQGVNDTTGDYSRGALGFWVDNGKIQY
                     PVSGITIAGNLKEMLLGIEHIGSDIDYRNNIKVGSVLIQQMTIAGEV"
     misc_feature    complement(909897..911138)
                     /gene="pmbA"
                     /locus_tag="COSY_0873"
                     /note="peptidase PmbA; Provisional; Region: PRK11040"
                     /db_xref="CDD:182922"
     gene            complement(911264..911962)
                     /locus_tag="COSY_0874"
                     /db_xref="GeneID:5171827"
     CDS             complement(911264..911962)
                     /locus_tag="COSY_0874"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219703.1"
                     /db_xref="GI:148245009"
                     /db_xref="GeneID:5171827"
                     /translation="MSILISVFIMGLLGGVHCLGMCGGIVGMLSAGLDPKVRSNPKKI
                     ALFHLNYNLGRILSYILLGAIFGLFGMLLTQVLQMSVFDKVLRIFSGMLMVMVGLYIG
                     NWSFNIQILEKFGAKFWVKLQPLTQQFLPIKNLRSAFFIGLLWGGIPCGLVYGALSFS
                     ILSGSMFEGSLIMLSFGLGTLPSLLLMSVLSTQMSFLIQKLWIRRLSGLLIIILGIMA
                     LWMPIQSMIFYDYI"
     misc_feature    complement(911363..911947)
                     /locus_tag="COSY_0874"
                     /note="Family description; Region: DsbD_2; pfam13386"
                     /db_xref="CDD:222093"
     gene            complement(911962..912810)
                     /gene="corC"
                     /locus_tag="COSY_0875"
                     /db_xref="GeneID:5172110"
     CDS             complement(911962..912810)
                     /gene="corC"
                     /locus_tag="COSY_0875"
                     /note="HlyC/CorC (HCC) family"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt efflux protein"
                     /protein_id="YP_001219704.1"
                     /db_xref="GI:148245010"
                     /db_xref="GeneID:5172110"
                     /translation="MNKEQFSLKSFFLQRLKKRYLHIPLRSSDELLRMLKEAEENYII
                     DSNSRSIIEGTMQLEKLEVRDVMVPKSKMVMIEHQSTTKELLDIMIKSSHSRFPIINS
                     DKNKIQGVILAKDLLGFLVEKQNFEFNYKQYLRDSLFVPESKTLGALLRDFQQKKSHM
                     AIVMDEYGEIAGLVTLEDVLEQIVGEIEDEHDLEEDNIIDFGEGRFLLKANTPIEEFD
                     EFFKVKLQVENLDTVAGLVIKGFTRLPEQMDEISLQGFNFKILKTDSRRIHLLEVERS
                     MNGNNA"
     misc_feature    complement(911986..912807)
                     /gene="corC"
                     /locus_tag="COSY_0875"
                     /note="Putative Mg2+ and Co2+ transporter CorC [Inorganic
                     ion transport and metabolism]; Region: CorC; COG4535"
                     /db_xref="CDD:226910"
     misc_feature    complement(912265..912600)
                     /gene="corC"
                     /locus_tag="COSY_0875"
                     /note="This cd contains two tandem repeats of the
                     cystathionine beta-synthase (CBS pair) domains associated
                     with the CorC_HlyC domain. CorC_HlyC is a transporter
                     associated domain. This small domain is found in Na+/H+
                     antiporters, in proteins involved in...; Region:
                     CBS_pair_CorC_HlyC_assoc; cd04590"
                     /db_xref="CDD:239963"
     misc_feature    complement(911986..912207)
                     /gene="corC"
                     /locus_tag="COSY_0875"
                     /note="Transporter associated domain; Region: CorC_HlyC;
                     smart01091"
                     /db_xref="CDD:215020"
     gene            complement(912849..913145)
                     /locus_tag="COSY_0876"
                     /db_xref="GeneID:5172140"
     CDS             complement(912849..913145)
                     /locus_tag="COSY_0876"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219705.1"
                     /db_xref="GI:148245011"
                     /db_xref="GeneID:5172140"
                     /translation="MKIEVVYALRDKQTLLELEISEGTTLQQAIKMSSILSIYPEIDL
                     IKQKTGIFGKIVKLDTVLREKDRIEIYRSLIADPKVVRKERAAQGKMMRSGKKT"
     misc_feature    complement(912876..913145)
                     /locus_tag="COSY_0876"
                     /note="hypothetical protein; Validated; Region: PRK01777"
                     /db_xref="CDD:234982"
     gene            complement(913135..913866)
                     /gene="hisA"
                     /locus_tag="COSY_0877"
                     /db_xref="GeneID:5172102"
     CDS             complement(913135..913866)
                     /gene="hisA"
                     /locus_tag="COSY_0877"
                     /EC_number="5.3.1.16"
                     /note="catalyzes the formation of
                     5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l-
                     (5-phosphoribosyl)imidazole-4-carboxamide from
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]
                     imidazole-4-carboxamide"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]
                     imidazole-4-carboxamide isomerase"
                     /protein_id="YP_001219706.1"
                     /db_xref="GI:148245012"
                     /db_xref="GeneID:5172102"
                     /translation="MIVIPAIDLKDGQCVRLRQGLMEDTTVFSSNPIEMATQWVEQGA
                     RRLHLVDLNGAFEGRPVNSTSITEIVSAFPDLPVQIGGGIRNIKIANTYIEAGVSYLI
                     IGTMAVTDSEFVSELCREFPNKVIVGLDANNGFVATKGWVQKTNLNVVDLSKKFEQDG
                     INSIIYTDIARDGMMQGMNVEAIVNLAKQISIPIIASGGITNIGDIIRLLTEVHFGIM
                     GVITGRAIYEGTLDFKQAQQLCDEN"
     misc_feature    complement(913153..913863)
                     /gene="hisA"
                     /locus_tag="COSY_0877"
                     /note="HisA.  Phosphoribosylformimino-5-aminoimidazole
                     carboxamide ribonucleotide (ProFAR) isomerase catalyzes
                     the fourth step in histidine biosynthesis, an
                     isomerisation of the aminoaldose moiety of ProFAR to the
                     aminoketose of PRFAR (N-(5&apos;-phospho-D-1...; Region:
                     HisA; cd04732"
                     /db_xref="CDD:240083"
     misc_feature    complement(913165..913860)
                     /gene="hisA"
                     /locus_tag="COSY_0877"
                     /note="phosphoribosylformimino-5-aminoimidazole
                     carboxamide ribotide isomerase; Region: TIGR00007"
                     /db_xref="CDD:232779"
     misc_feature    complement(order(913477..913479,913723..913725,
                     913843..913845))
                     /gene="hisA"
                     /locus_tag="COSY_0877"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:240083"
     gene            complement(915176..916201)
                     /gene="gcp"
                     /locus_tag="COSY_0878"
                     /db_xref="GeneID:5172439"
     CDS             complement(915176..916201)
                     /gene="gcp"
                     /locus_tag="COSY_0878"
                     /EC_number="3.4.24.57"
                     /note="in most organisms, only the N-terminal domain is
                     present in a single polypeptide; in some archaea this
                     domain is fused to a kinase domain; this gene is essential
                     for growth in Escherichia coli and Bacillus subtilis; the
                     secreted glycoprotease from Pasteurella haemolytica showed
                     specificity for O-sialoglycosylated proteins; the
                     Pyrococcus structure shows DNA-binding properties,
                     iron-binding, ATP-binding, and AP endonuclease activity"
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding/iron metalloprotein/AP
                     endonuclease"
                     /protein_id="YP_001219707.1"
                     /db_xref="GI:148245013"
                     /db_xref="GeneID:5172439"
                     /translation="MAKLDFITLGIESSCDETGVGLYHSELGLIGHKLFSSVEIHSEY
                     GGVVPELASRDHIQRVLPLIKTVLTNAKFTLQDLSGIAYTAGPGLAGALLVGSALAKS
                     LAWSLGVPSLAVHHMEGHLLAPLLEESQPKFPFVALLVSGGHTMLIDVKAIGQYKILG
                     KSLDDAVGEAFDKTAKILGLGYPGGPALEMLAKQGDTNTFKFPLPMVNRPGLDFSFSG
                     LKTFARNTFTKHPNKKSDIAKAFEVATTQILMIKCRRALEKTGRITLVVAGGVSANLS
                     LRSELNQMGRKVGVNIFYPRQEFCTDNGAMIALAGHFRLSDGQCDTNYEINIKPRWNI
                     EELSQIK"
     misc_feature    complement(915182..916183)
                     /gene="gcp"
                     /locus_tag="COSY_0878"
                     /note="UGMP family protein; Validated; Region: PRK09604"
                     /db_xref="CDD:236585"
     misc_feature    complement(<915860..916180)
                     /gene="gcp"
                     /locus_tag="COSY_0878"
                     /note="Inactive homolog of metal-dependent proteases,
                     putative molecular chaperone [Posttranslational
                     modification, protein turnover, chaperones]; Region:
                     COG1214; cl17884"
                     /db_xref="CDD:248438"
     gene            complement(916239..916961)
                     /locus_tag="COSY_0879"
                     /db_xref="GeneID:5172195"
     CDS             complement(916239..916961)
                     /locus_tag="COSY_0879"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="YP_001219708.1"
                     /db_xref="GI:148245014"
                     /db_xref="GeneID:5172195"
                     /translation="MTSNALIIQNISKSYSGRNVVNDVSFFVKSGEVVGLLGPNGAGK
                     TTCFYITCGLVKSNSGKVYLNNKRIDHLPMHKRADLGLSYLPQEPSIFRNLSVENNIM
                     AVLQLNSNFDKIQRVNRLEKLLREFSIEHIRHINGVSLSGGERRRVESARALAMNPKF
                     ILLDEPFSGVDPISVVDIQKIIFYLKDQDIGILITDHNYREMLDTCNNSYVLHNGVII
                     AKGSKEQILYNERVREVYLGRV"
     misc_feature    complement(916248..916946)
                     /locus_tag="COSY_0879"
                     /note="ATP-binding cassette component of YhbG transport
                     system; Region: ABC_YhbG; cd03218"
                     /db_xref="CDD:213185"
     misc_feature    complement(916248..916946)
                     /locus_tag="COSY_0879"
                     /note="ABC-type (unclassified) transport system, ATPase
                     component [General function prediction only]; Region:
                     YhbG; COG1137"
                     /db_xref="CDD:224060"
     misc_feature    complement(916827..916850)
                     /locus_tag="COSY_0879"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213185"
     misc_feature    complement(order(916371..916373,916467..916472,
                     916701..916703,916824..916832,916836..916841))
                     /locus_tag="COSY_0879"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213185"
     misc_feature    complement(916701..916712)
                     /locus_tag="COSY_0879"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213185"
     misc_feature    complement(916515..916544)
                     /locus_tag="COSY_0879"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213185"
     misc_feature    complement(916467..916484)
                     /locus_tag="COSY_0879"
                     /note="Walker B; other site"
                     /db_xref="CDD:213185"
     misc_feature    complement(916449..916460)
                     /locus_tag="COSY_0879"
                     /note="D-loop; other site"
                     /db_xref="CDD:213185"
     misc_feature    complement(916365..916385)
                     /locus_tag="COSY_0879"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213185"
     gene            complement(917232..917990)
                     /gene="birA"
                     /locus_tag="COSY_0880"
                     /db_xref="GeneID:5172092"
     CDS             complement(917232..917990)
                     /gene="birA"
                     /locus_tag="COSY_0880"
                     /EC_number="6.3.4.15"
                     /note="bifunctional biotin-[acetyl-CoA-carboxylase] ligase
                     / transcriptional repressor of biotin synthesis."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin biosynthesis protein BirA"
                     /protein_id="YP_001219709.1"
                     /db_xref="GI:148245015"
                     /db_xref="GeneID:5172092"
                     /translation="MNTYNYTNLSSYLSDDIQCFVFDSISSTNDYLAQLAFCMKTQVC
                     VTSEQTCGKGQYNRKWLSQKDASIILSIRRVFLSRILLSGLSLVVGLALVDVLEKYGI
                     FDLKLKWPNDLYFKDKKLAGILIENSLQGDYHSVIIGLGLNVDFNEDFQCETPWIDLK
                     KIILIPIDKLHLSKNLINKILEYLDIFESSGFDKFYNEWSKIDYLLGKQVKHTNKMQL
                     FSGTCLGINHEGVLLVETQCGIKLVYSSEFLHLY"
     misc_feature    complement(917562..917930)
                     /gene="birA"
                     /locus_tag="COSY_0880"
                     /note="Biotin/lipoate A/B protein ligase family; Region:
                     BPL_LplA_LipB; pfam03099"
                     /db_xref="CDD:217367"
     misc_feature    complement(917235..917927)
                     /gene="birA"
                     /locus_tag="COSY_0880"
                     /note="Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme
                     metabolism]; Region: BirA; COG0340"
                     /db_xref="CDD:223417"
     misc_feature    complement(917238..917375)
                     /gene="birA"
                     /locus_tag="COSY_0880"
                     /note="Biotin protein ligase C terminal domain; Region:
                     BPL_C; pfam02237"
                     /db_xref="CDD:216943"
     gene            918269..919012
                     /gene="truA"
                     /locus_tag="COSY_0881"
                     /db_xref="GeneID:5172500"
     CDS             918269..919012
                     /gene="truA"
                     /locus_tag="COSY_0881"
                     /EC_number="4.2.1.70"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine synthase A"
                     /protein_id="YP_001219710.1"
                     /db_xref="GI:148245016"
                     /db_xref="GeneID:5172500"
                     /translation="MKLALGVEYLGTHFHGWQCQKSNIRTVQQVIEQALSSVANQPVR
                     VFCSGRTDTGVHATCQVIHFETNIKRKNKAWLFGGNVHLPSDVNFTWVKPVDDNFHAR
                     FSVITRQYNYKIHNTKIRSSIIATHSLWEPRKLDIVAMNKAGQYLTGKHNFSAFRGSL
                     CQAKSPIKNIEFIKLTKHDDNILLDIKANAFLHHMVRNIVGTLLKVGKGEKPIEWVRE
                     VLNSKQRKQAGPTAPPQGLYFIRAFYKNI"
     misc_feature    918269..919000
                     /gene="truA"
                     /locus_tag="COSY_0881"
                     /note="tRNA pseudouridine synthase A; Validated; Region:
                     truA; PRK00021"
                     /db_xref="CDD:234577"
     misc_feature    918281..919000
                     /gene="truA"
                     /locus_tag="COSY_0881"
                     /note="Eukaryotic and bacterial pseudouridine synthases
                     similar to E.  coli TruA; Region: PseudoU_synth_EcTruA;
                     cd02570"
                     /db_xref="CDD:211337"
     misc_feature    order(918290..918292,918506..918508,918515..918538)
                     /gene="truA"
                     /locus_tag="COSY_0881"
                     /note="dimerization interface 3.5A [polypeptide binding];
                     other site"
                     /db_xref="CDD:211337"
     misc_feature    order(918413..918424,918857..918859)
                     /gene="truA"
                     /locus_tag="COSY_0881"
                     /note="active site"
                     /db_xref="CDD:211337"
     gene            919277..921220
                     /locus_tag="COSY_0882"
                     /db_xref="GeneID:5172033"
     CDS             919277..921220
                     /locus_tag="COSY_0882"
                     /note="sodium:sulfate symporter of divalent anion:Na+
                     symporter (DASS) family"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur deprivation response regulator"
                     /protein_id="YP_001219711.1"
                     /db_xref="GI:148245017"
                     /db_xref="GeneID:5172033"
                     /translation="MFNKKNISAIIFAIFAVWLSTIAPTTSISWMLGVLVLTIYLFAF
                     EVVEVDEAAITIMIILGLSSLPWIYTLMGLKEGLVDNQRLFDGFSSNAVMSIIAVMII
                     GAGLDKTGLMGKVATFILKIGGTSEPRVIPIISSTVGFISSFMQNVGAAALFIPVVSR
                     ISSRSGIPMSRLLMPMGFTAILGGTITMVGSSPLILLNDLILTTNQGLEVGQEMNTWG
                     LFSVTPIGIALVITGIIYFVIAGKFVLPVTKKEQLESVSAIEHFHKVYNIDYDLFEVN
                     VPTDSNLIGMMLDDIETTAKIRIIAIQTIEGETFIGHHSVERSTAIKPQMTLGVLTKK
                     EHLDTFIQEFHLKLSDTIEKFSNLLSTQECGTAEIVIPPNSSLINQSARDVWLRKTYG
                     IAMVALHRGGETMQEGEGIRNIPFQSGDTLIVHTRWIDLDRLQSNTDFIVITSEYPRQ
                     EEYRPEKIKWASIFFVIALFLVLFTDIKLSIALMTGALGMILSGVIKIEEAYRVVSWK
                     TVFLLASLIPLGMAVSKTGTALWIAQETVKVVGDMAPWVILTSIVILATFFTLVMSNV
                     GATILLVPIAVNIAIQVGENPAVYALAVAIATSNSFLIPTHQVNALIMGPGGYKVADF
                     IKAGGLMTVLFIIVMMSMMSIIF"
     misc_feature    919370..>919993
                     /locus_tag="COSY_0882"
                     /note="Anion permease ArsB/NhaD.  These permeases have
                     been shown to translocate sodium, arsenate, antimonite,
                     sulfate and organic anions across biological membranes in
                     all three kingdoms of life.  A typical anion permease
                     contains 8-13 transmembrane helices...; Region:
                     ArsB_NhaD_permease; cl17221"
                     /db_xref="CDD:247775"
     misc_feature    order(919391..919402,919421..919462,919544..919597,
                     919667..919717,919721..919774,919784..919855,
                     919943..919987)
                     /locus_tag="COSY_0882"
                     /note="transmembrane helices; other site"
                     /db_xref="CDD:238344"
     misc_feature    920090..920311
                     /locus_tag="COSY_0882"
                     /note="TrkA-C domain; Region: TrkA_C; pfam02080"
                     /db_xref="CDD:216867"
     misc_feature    <920375..921178
                     /locus_tag="COSY_0882"
                     /note="Di- and tricarboxylate transporters [Inorganic ion
                     transport and metabolism]; Region: CitT; COG0471"
                     /db_xref="CDD:223547"
     misc_feature    920375..920584
                     /locus_tag="COSY_0882"
                     /note="TrkA-C domain; Region: TrkA_C; pfam02080"
                     /db_xref="CDD:216867"
     misc_feature    <920711..921178
                     /locus_tag="COSY_0882"
                     /note="Anion permease ArsB/NhaD.  These permeases have
                     been shown to translocate sodium, arsenate, antimonite,
                     sulfate and organic anions across biological membranes in
                     all three kingdoms of life.  A typical anion permease
                     contains 8-13 transmembrane helices...; Region:
                     ArsB_NhaD_permease; cl17221"
                     /db_xref="CDD:247775"
     gene            921286..921876
                     /gene="cynT"
                     /locus_tag="COSY_0883"
                     /db_xref="GeneID:5172070"
     CDS             921286..921876
                     /gene="cynT"
                     /locus_tag="COSY_0883"
                     /EC_number="4.2.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="YP_001219712.1"
                     /db_xref="GI:148245018"
                     /db_xref="GeneID:5172070"
                     /translation="MQAKKRLIDGNQRFIDGTTTLHHQLPPHKHIKNIQDQKPFAIIL
                     GCSDSRVPIETIFDQNFGDLFIIRIAGNIVAPSQMGSVEFAISKFKTVLIVVLGHSNC
                     GAINATIDECINKTHLSSSLHSITDRIKPSILPLINLDLPNHELMNKAVKVNIINSVK
                     QLQSQSTIIKESMKNNKLKIIGANYSLASGMVQFLT"
     misc_feature    921289..921870
                     /gene="cynT"
                     /locus_tag="COSY_0883"
                     /note="Carbonic anhydrases (CA) are zinc-containing
                     enzymes that catalyze the reversible hydration of carbon
                     dioxide in a two-step mechanism in which the nucleophilic
                     attack of a zinc-bound hydroxide ion on carbon dioxide is
                     followed by the regeneration of an...; Region:
                     beta_CA_cladeC; cd03378"
                     /db_xref="CDD:239473"
     misc_feature    order(921394..921396,921400..921402,921421..921423,
                     921427..921435,921469..921471,921478..921480,
                     921535..921537,921550..921552,921580..921582,
                     921589..921591,921838..921840)
                     /gene="cynT"
                     /locus_tag="COSY_0883"
                     /note="active site clefts [active]"
                     /db_xref="CDD:239473"
     misc_feature    order(921421..921423,921427..921429,921580..921582,
                     921589..921591)
                     /gene="cynT"
                     /locus_tag="COSY_0883"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:239473"
     misc_feature    order(921424..921435,921439..921441,921445..921456,
                     921469..921477,921481..921483,921487..921489,
                     921520..921525,921532..921537,921838..921840,
                     921844..921849,921853..921855,921859..921861)
                     /gene="cynT"
                     /locus_tag="COSY_0883"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239473"
     gene            complement(921911..922321)
                     /gene="rimM"
                     /locus_tag="COSY_0884"
                     /db_xref="GeneID:5172154"
     CDS             complement(921911..922321)
                     /gene="rimM"
                     /locus_tag="COSY_0884"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="YP_001219713.1"
                     /db_xref="GI:148245019"
                     /db_xref="GeneID:5172154"
                     /translation="MNILSYQPWYINVDSHWQTLNISQGRVQAKTIVAQIKDIFDKEQ
                     ARVYIDINLYIKKSQLLRLKEGEYYWNDLIGLEVVNKAQFVLGKVFNLVDTGSNNVLV
                     VRGGKEHWVPYISPFLIQVDINNQIILVDWDENF"
     misc_feature    complement(921914..922318)
                     /gene="rimM"
                     /locus_tag="COSY_0884"
                     /note="16S rRNA-processing protein RimM; Provisional;
                     Region: rimM; PRK00122"
                     /db_xref="CDD:234650"
     misc_feature    complement(922145..>922318)
                     /gene="rimM"
                     /locus_tag="COSY_0884"
                     /note="RimM N-terminal domain; Region: RimM; pfam01782"
                     /db_xref="CDD:216696"
     misc_feature    complement(921929..922129)
                     /gene="rimM"
                     /locus_tag="COSY_0884"
                     /note="PRC-barrel domain; Region: PRC; pfam05239"
                     /db_xref="CDD:218519"
     gene            complement(922472..922762)
                     /gene="rpsP"
                     /locus_tag="COSY_0885"
                     /db_xref="GeneID:5172549"
     CDS             complement(922472..922762)
                     /gene="rpsP"
                     /locus_tag="COSY_0885"
                     /note="binds to lower part of 30S body where it stabilizes
                     two domains; required for efficient assembly of 30S; in
                     Escherichia coli this protein has nuclease activity"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="YP_001219714.1"
                     /db_xref="GI:148245020"
                     /db_xref="GeneID:5172549"
                     /translation="MVKIRLARGGAKKKPFYSIVATDSRRRRDSAYIERLGYFNPVTH
                     GQEVRLIIEEARLAYWTSKGAQISDRVKQLVKEFKDPLIRERDIAVKSAKNL"
     misc_feature    complement(922538..922762)
                     /gene="rpsP"
                     /locus_tag="COSY_0885"
                     /note="30S ribosomal protein S16; Reviewed; Region: rpsP;
                     PRK00040"
                     /db_xref="CDD:234588"
     gene            complement(922827..924203)
                     /gene="purB"
                     /locus_tag="COSY_0886"
                     /db_xref="GeneID:5171936"
     CDS             complement(922827..924203)
                     /gene="purB"
                     /locus_tag="COSY_0886"
                     /EC_number="4.3.2.2"
                     /note="Catalyzes two discrete reactions in the de novo
                     synthesis of purines: the cleavage of adenylosuccinate and
                     succinylaminoimidazole carboxamide ribotide"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="YP_001219715.1"
                     /db_xref="GI:148245021"
                     /db_xref="GeneID:5171936"
                     /translation="MKLTELTAISPIDGRYFEKTEILSSIFSEFGLIKYRVLIEVKWL
                     QDMADNIGIKEVSSFSQEATKFLDDIVTNFSLIDAQEVKMIEHTINHDVKAVEYFLKD
                     KIKGNSELEAVSEFFHFACTSEDINNLSYALMLLEGRNIMLTKMRELLSFIAKLAENN
                     VSVPMLSRTHGQTASPSTVGKEMANFAYRLKRQIEQLESVKIMGKFNGSVGNFNAHIC
                     AYPDLDWQYISQNFIESFGVNYAMYTTQIEPHDYIAEYFHSINRFNTVLIDFCRDIWG
                     YVSLGYFKQKTITGEVGSSTMPHKVNPIDFENGEGNLGIANAINMYLADKLAISRWQR
                     DLSDSTILRNLGVSCAHCLVAYASIVKGIGKLQSNKAKLTQDLDNSWEVLAEPIQTVM
                     RRYGIENPYEKLKDLTRGKTINAQVLVEFVKDLDIPDEAKITLFKLTPMTYTGDAQKL
                     AKAIKQLI"
     misc_feature    complement(922839..924203)
                     /gene="purB"
                     /locus_tag="COSY_0886"
                     /note="adenylosuccinate lyase; Provisional; Region:
                     PRK09285"
                     /db_xref="CDD:236452"
     misc_feature    complement(922869..924137)
                     /gene="purB"
                     /locus_tag="COSY_0886"
                     /note="PurB_like adenylosuccinases (adenylsuccinate lyase,
                     ASL); Region: PurB; cd01598"
                     /db_xref="CDD:176470"
     misc_feature    complement(order(922872..922874,923160..923162,
                     923175..923177,923181..923186,923196..923216,
                     923226..923231,923238..923243,923250..923255,
                     923259..923264,923271..923273,923283..923285,
                     923298..923303,923367..923372,923376..923381,
                     923385..923387,923397..923399,923418..923420,
                     923439..923441,923451..923453,923472..923477,
                     923481..923483,923550..923552,923559..923570,
                     923616..923621,923637..923642,923649..923651,
                     923658..923663,923679..923681,923685..923702,
                     923844..923849,923853..923858,923901..923903,
                     923928..923930,924117..924122))
                     /gene="purB"
                     /locus_tag="COSY_0886"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176470"
     misc_feature    complement(order(923283..923285,923298..923300,
                     923304..923306,923466..923468,923694..923696,
                     923850..923852,923931..923933))
                     /gene="purB"
                     /locus_tag="COSY_0886"
                     /note="active site"
                     /db_xref="CDD:176470"
     gene            924327..926903
                     /gene="acnB"
                     /locus_tag="COSY_0887"
                     /db_xref="GeneID:5172497"
     CDS             924327..926903
                     /gene="acnB"
                     /locus_tag="COSY_0887"
                     /EC_number="4.2.1.3"
                     /note="catalyzes the conversion of citrate to isocitrate
                     and the conversion of 2-methylaconitate to
                     2-methylisocitrate"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="YP_001219716.1"
                     /db_xref="GI:148245022"
                     /db_xref="GeneID:5172497"
                     /translation="MKSVYLEHVNKRQQNNLPPIALNKQQTESVIRHLIKDNHSSFYL
                     DLLTHQIPPGVDEASYIKANFLSSISKGDQSCHSISQTHATFLLGTMMGGYNIKPLIE
                     LLDIDATKENAQIALANTLLIYEAYQAIMDKSKNNIYARNVVQSWADAQWFNKKTPLS
                     DKIKLTVFRVEGEVNTDDLSPATQAWSRPDIPLHAQSMLIKKMNNPLKTIKKLKQKGL
                     PLVFVGDIVGTGSSRKSAINSVLWHIGQNINYIPNKRSGGIILGGKIAPIFFNTAQDS
                     GALPIECDVGKMRMGDKITIYPFKGKITNSKGEIISTFIISPTTLPDEVRAGGRIPLI
                     IGRGLTDKTRQDLGLPISTTFLRPQAGTEEQSISQSHTGYTLAQKIVGKACGVNGIYP
                     GTYCEPHMSSVGSQDTTGAMTRDELKELACLEFSADLVIQSFCHTAAYPKPIDLELQH
                     SLPNFMHSRGGVSLKPGDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVA
                     FSASIGMLPLNMPESILVRFTGTMQSGITLRDIVNAIPYTAIQRNLLTIDKSNKKNIF
                     SGRILEIEGLNDLKVEQAFELADASAERSANGCTIKLNKEPVIEYLRSNIALLSSMIN
                     KGYENKKTLARRIQAIQKWLEEPELLIADSDCKYASIIEINLNEIKEPILACPNDPDD
                     VKLLSELANTKIDEVFIGSCMTNISHFRMAAQMLKDELNIATELWIAPPTRMDKAQLK
                     AEGVYDIFNKLTKHVEIPGCSLCMGNQARVKNNSTVVSTSTRNFPNRLGNNTDVYLSS
                     AEVATITAKLGHIPTNIEYQQAIKSIKPIEEQIYQNLNFDQLEEYKDEINNLSLKNIL
                     NA"
     misc_feature    924327..926837
                     /gene="acnB"
                     /locus_tag="COSY_0887"
                     /note="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase; Validated; Region:
                     PRK09238"
                     /db_xref="CDD:236424"
     misc_feature    924828..925220
                     /gene="acnB"
                     /locus_tag="COSY_0887"
                     /note="Aconitase B swivel domain. Aconitate hydratase B is
                     involved in energy metabolism as part of the TCA cycle. It
                     catalyses the formation of cis-aconitate from citrate.
                     This is the aconitase swivel domain, which undergoes
                     swivelling conformational change in...; Region:
                     AcnB_Swivel; cd01576"
                     /db_xref="CDD:238808"
     misc_feature    925017..925025
                     /gene="acnB"
                     /locus_tag="COSY_0887"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238808"
     misc_feature    925452..926759
                     /gene="acnB"
                     /locus_tag="COSY_0887"
                     /note="Aconitate hydratase B catalyses the formation of
                     cis-aconitate from citrate as part of the TCA cycle;
                     Region: AcnB; cd01581"
                     /db_xref="CDD:153131"
     misc_feature    order(925542..925544,925551..925553,925791..925796,
                     926616..926618,926670..926672,926685..926687)
                     /gene="acnB"
                     /locus_tag="COSY_0887"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:153131"
     misc_feature    order(925797..925799,926430..926432,926604..926606,
                     926613..926618,926667..926669)
                     /gene="acnB"
                     /locus_tag="COSY_0887"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:153131"
     gene            complement(926960..927115)
                     /gene="rpmG"
                     /locus_tag="COSY_0888"
                     /db_xref="GeneID:5172455"
     CDS             complement(926960..927115)
                     /gene="rpmG"
                     /locus_tag="COSY_0888"
                     /note="in Escherichia coli BM108, a mutation that results
                     in lack of L33 synthesis had no effect on ribosome
                     synthesis or function; there are paralogous genes in
                     several bacterial genomes, and a CXXC motif for zinc
                     binding and an upstream regulation region of the paralog
                     lacking this motif that are regulated by zinc similar to
                     other ribosomal proteins like L31; the proteins in this
                     group lack the CXXC motif"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="YP_001219717.1"
                     /db_xref="GI:148245023"
                     /db_xref="GeneID:5172455"
                     /translation="MRETIKLVSSAKTGHFYTATKNKRLHPEKVEVKKFDPVVRKHVM
                     YKEVKIK"
     misc_feature    complement(926969..927115)
                     /gene="rpmG"
                     /locus_tag="COSY_0888"
                     /note="50S ribosomal protein L33; Validated; Region: rpmG;
                     PRK00595"
                     /db_xref="CDD:179075"
     gene            complement(927112..927360)
                     /gene="rpmB"
                     /locus_tag="COSY_0889"
                     /db_xref="GeneID:5172485"
     CDS             complement(927112..927360)
                     /gene="rpmB"
                     /locus_tag="COSY_0889"
                     /note="required for 70S ribosome assembly"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="YP_001219718.1"
                     /db_xref="GI:148245024"
                     /db_xref="GeneID:5172485"
                     /translation="MAKVCMVTGKRPISGNNVSHANNKTRRRFYPNLHKHRFWVESEN
                     RFVKLKLSAKGFRIIDKKGINIVLTEIRARGKFKESSL"
     misc_feature    complement(927136..927360)
                     /gene="rpmB"
                     /locus_tag="COSY_0889"
                     /note="50S ribosomal protein L28; Reviewed; Region: rpmB;
                     PRK00359"
                     /db_xref="CDD:234736"
     gene            927485..927574
                     /locus_tag="COSY_t32"
                     /db_xref="GeneID:5329752"
     tRNA            927485..927574
                     /locus_tag="COSY_t32"
                     /product="tRNA-Ser"
                     /db_xref="GeneID:5329752"
     gene            complement(928066..928689)
                     /gene="pyrE"
                     /locus_tag="COSY_0891"
                     /db_xref="GeneID:5172687"
     CDS             complement(928066..928689)
                     /gene="pyrE"
                     /locus_tag="COSY_0891"
                     /EC_number="2.4.2.10"
                     /note="involved in fifth step of pyrimidine biosynthesis;
                     converts orotidine 5'-phosphate and diphosphate to orotate
                     and 5-phospho-alpha-D-ribose 1-diphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="YP_001219719.1"
                     /db_xref="GI:148245025"
                     /db_xref="GeneID:5172687"
                     /translation="MEQYQEDFVEFILDSGALKFGNFTLKSGRISPYFFNVGVFNTGQ
                     YLSQLGKFYAIAIENSGLDFDVLFGPSYKGIPLVTATAVAFNNNFNKDVSYSFNRKEV
                     KTYGEGGGIVGHSLEGNILIIDDVITAGTAIHEAVDIIKANGATVKGVIVAVDRQEKG
                     KSGQSAIQEVEQNFGISVFSIINLSNVVDYLKQGNNHALIDRIEVQR"
     misc_feature    complement(928207..928545)
                     /gene="pyrE"
                     /locus_tag="COSY_0891"
                     /note="Phosphoribosyl transferase (PRT)-type I domain;
                     Region: PRTases_typeI; cd06223"
                     /db_xref="CDD:206754"
     misc_feature    complement(order(928222..928224,928294..928308,
                     928312..928320,928471..928473,928477..928479))
                     /gene="pyrE"
                     /locus_tag="COSY_0891"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            928715..929485
                     /gene="xthA"
                     /locus_tag="COSY_0892"
                     /db_xref="GeneID:5172423"
     CDS             928715..929485
                     /gene="xthA"
                     /locus_tag="COSY_0892"
                     /EC_number="3.1.11.2"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="YP_001219720.1"
                     /db_xref="GI:148245026"
                     /db_xref="GeneID:5172423"
                     /translation="MIRIITTNVNGIRAAERKGFLNWIKNQNADVVCLQEIKATEEQL
                     DERFYPEEYHCYYQPAQKKGYSGTTIFTKQTPIQVIKESPWKDINFEGRFIQVNFKNF
                     SVISIYIHSGSAKQARQNLKMEFLTERFMPYLQELKISGRKVIICGDMNIVHQERDIK
                     NWKANQKNSGCLPEERAWLDKLFFKVGFIDGFREVNQEDQQYTWWSNRGQAWANNIGW
                     RIDYQILTPNLKGKVKNANIYKNKRFSDHAPIIMDYQL"
     misc_feature    928718..929476
                     /gene="xthA"
                     /locus_tag="COSY_0892"
                     /note="Neisseria meningitides Nape-like subfamily of the
                     ExoIII family purinic/apyrimidinic (AP) endonucleases;
                     Region: Nape_like_AP-endo; cd10281"
                     /db_xref="CDD:197336"
     misc_feature    order(928736..928738,928742..928759,928820..928822,
                     928826..928828,928841..928843,928904..928909,
                     928991..928993,929036..929038,929045..929047,
                     929051..929053,929066..929068,929159..929161,
                     929165..929167,929195..929197,929201..929203,
                     929207..929209,929324..929326,929330..929338,
                     929342..929344,929354..929356,929360..929362,
                     929366..929368,929372..929377,929444..929446,
                     929450..929455)
                     /gene="xthA"
                     /locus_tag="COSY_0892"
                     /note="putative active site [active]"
                     /db_xref="CDD:197336"
     misc_feature    order(928736..928738,928820..928822,929036..929038,
                     929159..929161,929165..929167,929375..929377,
                     929450..929455)
                     /gene="xthA"
                     /locus_tag="COSY_0892"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:197336"
     misc_feature    order(928736..928738,928742..928759,928820..928822,
                     928826..928828,928841..928843,928904..928909,
                     928991..928993,929036..929038,929045..929047,
                     929051..929053,929066..929068,929159..929161,
                     929165..929167,929195..929197,929201..929203,
                     929207..929209,929324..929326,929330..929338,
                     929354..929356,929360..929362,929366..929368,
                     929372..929374,929444..929446,929453..929455)
                     /gene="xthA"
                     /locus_tag="COSY_0892"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:197336"
     misc_feature    order(928736..928738,928820..928822,929036..929038,
                     929045..929047,929159..929161,929165..929167,
                     929453..929455)
                     /gene="xthA"
                     /locus_tag="COSY_0892"
                     /note="putative phosphate binding site [ion binding];
                     other site"
                     /db_xref="CDD:197336"
     misc_feature    order(928742..928744,928820..928822,929450..929452)
                     /gene="xthA"
                     /locus_tag="COSY_0892"
                     /note="metal binding site A [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:197336"
     misc_feature    order(929036..929038,929045..929047,929159..929161,
                     929165..929167,929324..929326,929366..929368,
                     929372..929374,929453..929455)
                     /gene="xthA"
                     /locus_tag="COSY_0892"
                     /note="putative AP binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:197336"
     misc_feature    order(929159..929161,929165..929167,929453..929455)
                     /gene="xthA"
                     /locus_tag="COSY_0892"
                     /note="putative metal binding site B [ion binding]; other
                     site"
                     /db_xref="CDD:197336"
     gene            930228..930911
                     /locus_tag="COSY_0893"
                     /db_xref="GeneID:5171927"
     CDS             930228..930911
                     /locus_tag="COSY_0893"
                     /note="SAM-dependent methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine-dependent
                     methyltransferase"
                     /protein_id="YP_001219721.1"
                     /db_xref="GI:148245027"
                     /db_xref="GeneID:5171927"
                     /translation="MINQIRKIKSFVRRPGRLTLGQKMGLTKFWEDHGIDLPKGKINL
                     NTLFVKQQKIVLEVGFGNGDSLLKMAINTPDRNFLGIEVYEAGVGQLINKAHKYQLNN
                     LKIIKEDAVKVLTNHIEDSSFNLFQMFFPDPWHKKRHFKRRLVQTDFLNLLSHKMIKS
                     GKIHIVTDSKHYAIHMMTVLERHPNFKNTQNAPIYSPRPEHQPITKFEQRSHRLGHDV
                     WNLIFTNEK"
     misc_feature    930249..930869
                     /locus_tag="COSY_0893"
                     /note="tRNA (guanine-N(7)-)-methyltransferase; Reviewed;
                     Region: trmB; PRK00121"
                     /db_xref="CDD:234649"
     gene            930913..931365
                     /locus_tag="COSY_0894"
                     /db_xref="GeneID:5172038"
     CDS             930913..931365
                     /locus_tag="COSY_0894"
                     /note="suppresses F exclusion of bacteriophage T7"
                     /codon_start=1
                     /transl_table=11
                     /product="FxsA protein"
                     /protein_id="YP_001219722.1"
                     /db_xref="GI:148245028"
                     /db_xref="GeneID:5172038"
                     /translation="MIFPIFVVMTLLEIYILASVGAAIGGFLTVLLVIITAFIGFFLL
                     KQQGYSTIAKAQNTISNNQTSTFVRLEGVVIVVSGVLLLTPGFITDMIGLLGLLPFSR
                     SYFINRILEKNAKKIFNNNHSGSIIKTQNNQPQQSNEKNTIEGEFWED"
     misc_feature    930919..931281
                     /locus_tag="COSY_0894"
                     /note="FxsA cytoplasmic membrane protein; Region: FxsA;
                     pfam04186"
                     /db_xref="CDD:217949"
     gene            931353..932567
                     /gene="folC"
                     /locus_tag="COSY_0895"
                     /db_xref="GeneID:5171995"
     CDS             931353..932567
                     /gene="folC"
                     /locus_tag="COSY_0895"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /note="bifunctional dihydrofolate synthase /
                     folylpolyglutamate synthase."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folate biosynthesis protein FolC"
                     /protein_id="YP_001219723.1"
                     /db_xref="GI:148245029"
                     /db_xref="GeneID:5171995"
                     /translation="MGGLNTLSDWLNYQDNLHFKKIDLGLERVTKVYKKLFPKGILFQ
                     VITVAGTNGKGSTVAFIDSIYQQSNFKVGKFSSPHILKYNERFVINGIQATDEKICSA
                     FNKIEQIREKTSLTYFEFSTLAALIIFELEKVDVAVLEVGIGGRLDSVNIVDNNVGVI
                     TNIDIDHVDYLGNTRELIGYEKAGIMRKNTPCICADINPPTSINQYAHQIKAQLEFVK
                     QRYTGDIGLISKHQQQNAATAILTVQKLNKTLPINANEIKRGIKYVKLNARFQIETIH
                     NKTFIFDVAHNVAAVKVLSAELAKQKCPTIAIFSALKDKNIGLMINKISMVINQWLLV
                     PLNVNRAISMQTLSKQFNLAHNIQICNDMQDAINHGINDKQYRRIVIFGSFYVVANAL
                     KILTPFMKNNKE"
     misc_feature    931368..932537
                     /gene="folC"
                     /locus_tag="COSY_0895"
                     /note="Folylpolyglutamate synthase [Coenzyme metabolism];
                     Region: FolC; COG0285"
                     /db_xref="CDD:223362"
     misc_feature    931500..>931946
                     /gene="folC"
                     /locus_tag="COSY_0895"
                     /note="Mur ligase middle domain; Region: Mur_ligase_M;
                     pfam08245"
                     /db_xref="CDD:219763"
     gene            932613..933464
                     /locus_tag="COSY_0896"
                     /db_xref="GeneID:5171813"
     CDS             932613..933464
                     /locus_tag="COSY_0896"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219724.1"
                     /db_xref="GI:148245030"
                     /db_xref="GeneID:5171813"
                     /translation="MMNEFFITIWNMIERLVWSDWITIAILAIFLVLGFKRGLAKELI
                     NLGFLLLAILITLLFYQVLATSSLITWLMLSHQSHLTISFWIIFICIVIIKKLIYKLT
                     QLSLTINNPCVLNKLFALMVLFTAITIFSCHHLDIVAGLDIIEVFIDNKYIRISVSFI
                     ILFSSIFGIFTFISKILNISIDKTKPCFLSSFFEKILKILQAMDIKLNARNINSTQNS
                     ILGSMMGLIKANLAILIIVLMLQNISWVSQQYYWIETNGALRIFQDIASNIKPVLSQY
                     LLFINNN"
     gene            933475..934992
                     /gene="purF"
                     /locus_tag="COSY_0897"
                     /db_xref="GeneID:5171971"
     CDS             933475..934992
                     /gene="purF"
                     /locus_tag="COSY_0897"
                     /EC_number="2.4.2.14"
                     /note="Catalyzes first step of the de novo purine
                     nucleotide biosynthetic pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="YP_001219725.1"
                     /db_xref="GI:148245031"
                     /db_xref="GeneID:5171971"
                     /translation="MCGIVGILSTTKKDIAVYIYDALTILQHRGQDAAGIVTAYKGRF
                     YMRKSNGLVKNVFRTKHMTQLLGNMGIGHVRYPTSGSSSNAEVQPFYVNSPYGITFAH
                     NGNLTNTEQLSQELFEQDLRHINTNSDSEILLNVFASELAKLQKQRINESDIFNSVSQ
                     VHKRVRGAYAAIGMIPGYGIFGFRDPNGIRPLILGKCITKGGTKYMLASESVALRALG
                     YKITQDIKPGEAVVIDRIGNIFIKQCTEKAKYSPCIFEFVYFARPDSVIDNISVYKSR
                     LRMGEKLAEKINKEWNIDNIDVIIPIPDTSRVAALQLAHKLDVKYSEGLIRNRYIART
                     FIMPGQKLRKKSVRQKLSTIELEFKNKNVLLVDDSIVRGTTSEQIVQMARDAGANKVF
                     FASAAPVVRYPNVYGIDMASNKEFIAHNRNIDQICKAIGADKLIYQDLDDLIWCVQQG
                     NNAITTFDCSCFNGQYVTNDIDQDYLEHIEFLRGNSTKKNNNTCEASELIGNDVE"
     misc_feature    933475..934983
                     /gene="purF"
                     /locus_tag="COSY_0897"
                     /note="amidophosphoribosyltransferase; Provisional;
                     Region: PRK09246"
                     /db_xref="CDD:236427"
     misc_feature    933478..934278
                     /gene="purF"
                     /locus_tag="COSY_0897"
                     /note="Glutamine amidotransferases class-II (GN-AT)_GPAT-
                     type. This domain is found at the N-terminus of  glutamine
                     phosphoribosylpyrophosphate (Prpp) amidotransferase
                     (GPATase) . The glutaminase domain catalyzes amide
                     nitrogen transfer from glutamine to the...; Region:
                     GPATase_N; cd00715"
                     /db_xref="CDD:238367"
     misc_feature    order(933478..933480,933559..933564,933697..933699,
                     933781..933786,933859..933861)
                     /gene="purF"
                     /locus_tag="COSY_0897"
                     /note="active site"
                     /db_xref="CDD:238367"
     misc_feature    order(933532..933537,933544..933546,933565..933567,
                     933748..933750,933865..933867,933874..933879,
                     933886..933891)
                     /gene="purF"
                     /locus_tag="COSY_0897"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238367"
     misc_feature    934309..934671
                     /gene="purF"
                     /locus_tag="COSY_0897"
                     /note="Phosphoribosyl transferase (PRT)-type I domain;
                     Region: PRTases_typeI; cd06223"
                     /db_xref="CDD:206754"
     misc_feature    order(934375..934377,934381..934383,934573..934581,
                     934585..934599,934669..934671)
                     /gene="purF"
                     /locus_tag="COSY_0897"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            935018..936184
                     /gene="metB"
                     /locus_tag="COSY_0898"
                     /db_xref="GeneID:5172436"
     CDS             935018..936184
                     /gene="metB"
                     /locus_tag="COSY_0898"
                     /EC_number="4.2.99.-"
                     /note="cystathionine gamma-synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="O-succinylhomoserine sulfhydrylase"
                     /protein_id="YP_001219726.1"
                     /db_xref="GI:148245032"
                     /db_xref="GeneID:5172436"
                     /translation="MKDLSFNTKAIRTGYKTTTEQEHSEAIFLTSSFVFSSAEQAANR
                     FSKKDPGNIYARFTNPTVDAFEKKLAILEGAQACVATSSGMAAIFATIMALFKSGDHI
                     VASRNMFGTSIIMLNTIITKFNIDISFVNLSDLSAWENTLKNNTKLFLLETPSNPLGE
                     VVNINALSRISKANSILLAVDNTILSPALQTPITLGADIVIHSATKYIDGQGRCLAGV
                     IAGSTDIIEQIHRFLRTTGPSLSAFNAWIVLKGLDTLSLRMKAHSDNALKLAIWLEAQ
                     DQVEKVYYLGLPSHPDHNLAKSQQSGFGGIVSFKIKGGKKSAFKIINATNILSITANL
                     GDTKSTITHPATTTHGRLTDEERLNAHITDGLIRISVGLEDIKDIIADIKQTLV"
     misc_feature    935018..936166
                     /gene="metB"
                     /locus_tag="COSY_0898"
                     /note="O-succinylhomoserine sulfhydrylase; Validated;
                     Region: PRK08133"
                     /db_xref="CDD:181244"
     misc_feature    935096..936178
                     /gene="metB"
                     /locus_tag="COSY_0898"
                     /note="CGS_like: Cystathionine gamma-synthase is a PLP
                     dependent enzyme and catalyzes the committed step of
                     methionine biosynthesis. This pathway is unique to
                     microorganisms and plants, rendering the enzyme an
                     attractive target for the development of...; Region:
                     CGS_like; cd00614"
                     /db_xref="CDD:99738"
     misc_feature    order(935102..935113,935117..935122,935177..935179,
                     935183..935185,935261..935266,935270..935275,
                     935342..935344,935357..935359,935366..935368,
                     935630..935632,935654..935656,935660..935662,
                     935708..935710,935738..935740,935744..935749,
                     935984..935986)
                     /gene="metB"
                     /locus_tag="COSY_0898"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99738"
     misc_feature    order(935264..935272,935342..935344,935471..935473,
                     935558..935560,935624..935626,935630..935635,
                     935660..935662)
                     /gene="metB"
                     /locus_tag="COSY_0898"
                     /note="substrate-cofactor binding pocket; other site"
                     /db_xref="CDD:99738"
     misc_feature    order(935264..935272,935342..935344,935558..935560,
                     935567..935569,935624..935626,935630..935635)
                     /gene="metB"
                     /locus_tag="COSY_0898"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99738"
     misc_feature    935633..935635
                     /gene="metB"
                     /locus_tag="COSY_0898"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99738"
     gene            936213..936722
                     /gene="fabA"
                     /locus_tag="COSY_0899"
                     /db_xref="GeneID:5172551"
     CDS             936213..936722
                     /gene="fabA"
                     /locus_tag="COSY_0899"
                     /EC_number="4.2.1.60"
                     /note="catalyzes the dehydration of
                     (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or
                     3,4-decenoyl-ACP"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxydecanoyl-(acyl carrier protein)
                     dehydratase"
                     /protein_id="YP_001219727.1"
                     /db_xref="GI:148245033"
                     /db_xref="GeneID:5172551"
                     /translation="MQNSFSYNELIKCGDGELFGLGNAQLPKPPMLMFDRISHISNDG
                     GEYGKGEIIAELDINPNLWFFKCHFNEDPVMPGCLGLDAMWQLIGFYLGWLGGPGRGR
                     ALGAGNIKFVGQVLPSAKKVTYKIDLSRVIARKLYMGVADATMEVDSKVIYEATNLKV
                     GLFTDTSKM"
     misc_feature    936282..936707
                     /gene="fabA"
                     /locus_tag="COSY_0899"
                     /note="FabA, beta-hydroxydecanoyl-acyl carrier protein
                     (ACP)-dehydratase: Bacterial protein of the type II, fatty
                     acid synthase system that binds ACP and catalyzes both
                     dehydration and isomerization reactions, apparently in the
                     same active site. The FabA...; Region: FabA; cd01287"
                     /db_xref="CDD:238614"
     misc_feature    order(936282..936290,936456..936458,936465..936470,
                     936477..936482,936513..936524)
                     /gene="fabA"
                     /locus_tag="COSY_0899"
                     /note="active site 1 [active]"
                     /db_xref="CDD:238614"
     misc_feature    order(936285..936287,936291..936293,936444..936446,
                     936456..936458,936513..936539,936543..936545,
                     936549..936554)
                     /gene="fabA"
                     /locus_tag="COSY_0899"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238614"
     misc_feature    order(936435..936443,936543..936554)
                     /gene="fabA"
                     /locus_tag="COSY_0899"
                     /note="active site 2 [active]"
                     /db_xref="CDD:238614"
     gene            936722..937936
                     /gene="fabB"
                     /locus_tag="COSY_0900"
                     /db_xref="GeneID:5172488"
     CDS             936722..937936
                     /gene="fabB"
                     /locus_tag="COSY_0900"
                     /EC_number="2.3.1.41"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase I/II"
                     /protein_id="YP_001219728.1"
                     /db_xref="GI:148245034"
                     /db_xref="GeneID:5172488"
                     /translation="MHRVVVTGMGVVSSLGVNCAEVLNSLKTSKSGIKFNKTQENIGL
                     RSHLSGTISEINSDEIIDRKMKRFMADAAIYNAVALDEAIKQSGLTKVQISNERTGLI
                     MGSGGASNQNIVEATDILRKKGIKRVGPYRVPRTMGSTTSACLSTLFKIKGINYSISS
                     ACSTSAHCIGNAMEQIQMGKQDVVFAGGGEELDWSLTMLFDAMGALSSKYNKFPEQAS
                     RAFDKGRDGFIISGGGGALALESLEYAQARGATILAELTGYGATSDGYDMVVPSGDGA
                     KRCMEIAISTVNGPINYINAHGTSTPIGDIKELNAIKEVFGDNIPNISSTKSLSGHAL
                     GAAGVNESIYSLLMLQNNFMTKSVNINILDEAAKGMPIIQTTIKQTFNRVMSNSFGFG
                     GTNACLVFEKFK"
     misc_feature    936722..937933
                     /gene="fabB"
                     /locus_tag="COSY_0900"
                     /note="3-oxoacyl-(acyl carrier protein) synthase I;
                     Reviewed; Region: PRK07967"
                     /db_xref="CDD:181184"
     misc_feature    936725..937921
                     /gene="fabB"
                     /locus_tag="COSY_0900"
                     /note="Beta-ketoacyl-acyl carrier protein (ACP) synthase
                     (KAS), type I and II. KASs are responsible for the
                     elongation steps in fatty acid biosynthesis. KASIII
                     catalyses the initial condensation and KAS I and II
                     catalyze further elongation steps by Claisen...; Region:
                     KAS_I_II; cd00834"
                     /db_xref="CDD:238430"
     misc_feature    order(937037..937039,937058..937063,937073..937075,
                     937079..937084,937118..937120,937136..937138,
                     937148..937150,937160..937162,937178..937180,
                     937184..937186,937190..937198,937232..937234,
                     937241..937246,937253..937255,937316..937318,
                     937325..937330,937505..937519,937553..937555,
                     937895..937897,937901..937903)
                     /gene="fabB"
                     /locus_tag="COSY_0900"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238430"
     misc_feature    order(937205..937207,937610..937612,937715..937717)
                     /gene="fabB"
                     /locus_tag="COSY_0900"
                     /note="active site"
                     /db_xref="CDD:238430"
     gene            complement(938378..939292)
                     /gene="secF"
                     /locus_tag="COSY_0901"
                     /db_xref="GeneID:5172493"
     CDS             complement(938378..939292)
                     /gene="secF"
                     /locus_tag="COSY_0901"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase SecF subunit"
                     /protein_id="YP_001219729.1"
                     /db_xref="GI:148245035"
                     /db_xref="GeneID:5172493"
                     /translation="MSFKVLNIPTINFIGKRTYAIIFSVLLISVSIFSLTTKGLKLGI
                     DFKGGTLIEVGYQQSVDLAEIRAILVNANFKRANVQYFGSTNEILIRLEPQLISNAKL
                     SSKIIYLLGDDVDIRRVEFVGPKVGEELTNDGGLAMLYALIGILIYVLFRFEYRFSLG
                     SIAALIHDVIIILGVFSLFQIEFDLTVLAAILAVIGYSLNDTIVVFDRIRENFLLTHH
                     VESSRIINDALNQTLSRTITTSLTTLLVLLALFFLGGEIIHNFSLALLIGVVIGTYSS
                     IYVASLMILELGITKENLFSSDKSKSRP"
     misc_feature    complement(938411..939265)
                     /gene="secF"
                     /locus_tag="COSY_0901"
                     /note="preprotein translocase subunit SecF; Reviewed;
                     Region: secF; PRK13022"
                     /db_xref="CDD:237275"
     misc_feature    complement(939107..939187)
                     /gene="secF"
                     /locus_tag="COSY_0901"
                     /note="SecD/SecF GG Motif; Region: Sec_GG; pfam07549"
                     /db_xref="CDD:219463"
     misc_feature    complement(938429..938965)
                     /gene="secF"
                     /locus_tag="COSY_0901"
                     /note="Protein export membrane protein; Region: SecD_SecF;
                     pfam02355"
                     /db_xref="CDD:216990"
     gene            complement(939289..941136)
                     /gene="secD"
                     /locus_tag="COSY_0902"
                     /db_xref="GeneID:5171834"
     CDS             complement(939289..941136)
                     /gene="secD"
                     /locus_tag="COSY_0902"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase SecD subunit"
                     /protein_id="YP_001219730.1"
                     /db_xref="GI:148245036"
                     /db_xref="GeneID:5171834"
                     /translation="MNHYSWHKNALIVFVLLLSILYALPNIFGSDLAIQVSSVDNALI
                     VDQDLVKIKNVLKIQQIKFKSIELINQRILVRFKNKMQQLLAKDALNKALSRSYVVAL
                     NLAPSVPVWLASLGGKAMSLGLDLRGGVHFLLEVDMKAVISASMDTAYNELRVLLRKD
                     RLYKSIKQKGNSIVIHFKRSELKDEASQLIKSELSDLVLLSNTDDLLLNIGISESVQK
                     QAKKSALKQNITTLRNRVNELGVAEPIIQQQGLERIVVQLPGVQDTARAKEILGAVAT
                     LEFRLVDEKNDPQIAIQSGRLPIGSKLYYFKDGRPLLLKSHVITTGENITGATSGVHQ
                     ENNTPMVNITLDSAGGRAMFNTTKKYLHHRMAVVFIENKVETIVKNGKTIKKRTTTRD
                     IINAATIKGIFSSRFQVTGIDNIKEARNLALLLRAGSLSAPIEIIEERTIGPSLGSDN
                     ITKGVISILVGFILVLLFMAMRYQLFGMVANVALTLNLVMILSILSLLQATLTLPGIA
                     GIVLTVGMAVDANVLIFERIKEEMVINRNLPKAISVGYDKALLTILDANITTLIAALI
                     LFSFGTGVIKGFAITLSIGIITSMFTAIIVSRAIINKIYSGKKLEEISI"
     misc_feature    complement(940831..941136)
                     /gene="secD"
                     /locus_tag="COSY_0902"
                     /note="SecD export protein N-terminal TM region; Region:
                     SecD-TM1; pfam13721"
                     /db_xref="CDD:222341"
     misc_feature    complement(939292..940830)
                     /gene="secD"
                     /locus_tag="COSY_0902"
                     /note="preprotein translocase subunit SecD; Reviewed;
                     Region: secD; PRK05812"
                     /db_xref="CDD:235615"
     misc_feature    complement(940711..940806)
                     /gene="secD"
                     /locus_tag="COSY_0902"
                     /note="SecD/SecF GG Motif; Region: Sec_GG; pfam07549"
                     /db_xref="CDD:219463"
     misc_feature    complement(939355..939837)
                     /gene="secD"
                     /locus_tag="COSY_0902"
                     /note="protein-export membrane protein, SecD/SecF family;
                     Region: 2A0604s01; TIGR00916"
                     /db_xref="CDD:233183"
     gene            complement(941152..941493)
                     /gene="yajC"
                     /locus_tag="COSY_0903"
                     /db_xref="GeneID:5171818"
     CDS             complement(941152..941493)
                     /gene="yajC"
                     /locus_tag="COSY_0903"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase YajC subunit"
                     /protein_id="YP_001219731.1"
                     /db_xref="GI:148245037"
                     /db_xref="GeneID:5171818"
                     /translation="MNLLDLIIVPVFAEGLVSESSILDSWSGLPFLLVMFALMYFLLI
                     RPQQKRAKEHKTLLVALKTGDEVVTNGGIIGKVVSVDESFAILEIANGILVKVQKQGI
                     NQKMPKGSAKI"
     misc_feature    complement(941158..941418)
                     /gene="yajC"
                     /locus_tag="COSY_0903"
                     /note="preprotein translocase subunit YajC; Validated;
                     Region: yajC; PRK05585"
                     /db_xref="CDD:235518"
     gene            complement(941515..942804)
                     /gene="serS"
                     /locus_tag="COSY_0904"
                     /db_xref="GeneID:5172052"
     CDS             complement(941515..942804)
                     /gene="serS"
                     /locus_tag="COSY_0904"
                     /EC_number="6.1.1.11"
                     /note="catalyzes a two-step reaction, first charging a
                     serine molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="seryl-tRNA synthetase"
                     /protein_id="YP_001219732.1"
                     /db_xref="GI:148245038"
                     /db_xref="GeneID:5172052"
                     /translation="MLSKKQLRLDMKAVANALKKRYFYFDVDHLIELESNRKKNQIET
                     QNLQNLRNMQSKAIGKAKASGEDIKSLLKNVSDLSTKLNLAKSNLQLIQSEIDVIVLS
                     MPNIPHHSVPNGKSEEDNIEVSKWGKLVNYDFDVKDHVDLGAMYGLDFETAVKISGAR
                     FSVMTGKIARLHRALTQFMLDRHSEVNGYTEAYVPYLVNTESLIGTGQLPKFEADLFK
                     TYLHGEKGETKTLYLIPTGEVPVTNMMRDMIIKENDLPLKFVTHTPSFRSEAGSYGRY
                     TRGLIRQHQFEKVELVQVVKAQDSYQALEVLTTHAEDILQALELPYRKISLCAGDLGF
                     SATKTYDLEVWLPGQNVYCEISSCSCFEDFQARRLQLRYKNKETNKLELLHTLNGSGL
                     AVGRTLVAVLENHQQADRSIKIPFVLQSYMGGLEVMN"
     misc_feature    complement(941524..942804)
                     /gene="serS"
                     /locus_tag="COSY_0904"
                     /note="seryl-tRNA synthetase; Provisional; Region:
                     PRK05431"
                     /db_xref="CDD:235461"
     misc_feature    complement(942484..942804)
                     /gene="serS"
                     /locus_tag="COSY_0904"
                     /note="Seryl-tRNA synthetase N-terminal domain; Region:
                     Seryl_tRNA_N; pfam02403"
                     /db_xref="CDD:217020"
     misc_feature    complement(941539..942450)
                     /gene="serS"
                     /locus_tag="COSY_0904"
                     /note="Seryl-tRNA synthetase (SerRS) class II core
                     catalytic domain. SerRS is responsible for the attachment
                     of serine to the 3&apos; OH group of ribose of the
                     appropriate tRNA. This domain It is primarily responsible
                     for ATP-dependent formation of the enzyme...; Region:
                     SerRS_core; cd00770"
                     /db_xref="CDD:238393"
     misc_feature    complement(order(941539..941544,941950..941952,
                     942013..942015,942061..942063,942073..942075,
                     942085..942087,942112..942114,942124..942126,
                     942151..942156,942208..942210,942214..942222,
                     942226..942237,942274..942276,942283..942285,
                     942289..942291,942295..942297,942307..942327,
                     942334..942351))
                     /gene="serS"
                     /locus_tag="COSY_0904"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238393"
     misc_feature    complement(order(941617..941619,941635..941637,
                     941641..941643,941734..941745,941935..941937,
                     941941..941943,941947..941949,941956..941958,
                     941962..941964,941971..941973,941980..941982,
                     941998..942000,942004..942006,942091..942093,
                     942097..942099,942328..942330))
                     /gene="serS"
                     /locus_tag="COSY_0904"
                     /note="active site"
                     /db_xref="CDD:238393"
     misc_feature    complement(942214..942237)
                     /gene="serS"
                     /locus_tag="COSY_0904"
                     /note="motif 1; other site"
                     /db_xref="CDD:238393"
     misc_feature    complement(941998..942009)
                     /gene="serS"
                     /locus_tag="COSY_0904"
                     /note="motif 2; other site"
                     /db_xref="CDD:238393"
     misc_feature    complement(order(941617..941619,941626..941634))
                     /gene="serS"
                     /locus_tag="COSY_0904"
                     /note="motif 3; other site"
                     /db_xref="CDD:238393"
     gene            942804..943175
                     /locus_tag="COSY_0905"
                     /db_xref="GeneID:5171898"
     CDS             942804..943175
                     /locus_tag="COSY_0905"
                     /note="Rhodanese is a sulphurtransferase involved in
                     cyanide detoxification."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese family protein"
                     /protein_id="YP_001219733.1"
                     /db_xref="GI:148245039"
                     /db_xref="GeneID:5171898"
                     /translation="MLYNNFIIYIICLNTPGLTLKTNFGNYTMFNSFSSNDACQLLAN
                     GAQLVDVRSSNEFAQGALPNAINLPLQSIMTADRIIDRNKAVILYCVTGIRSSTAKNY
                     LIQMGYKNVNDLGSFKNYNCE"
     misc_feature    942924..943136
                     /locus_tag="COSY_0905"
                     /note="Rhodanese Homology Domain (RHOD); an alpha beta
                     fold domain found duplicated in the rhodanese protein. The
                     cysteine containing enzymatically active version of the
                     domain is also found in the Cdc25 class of protein
                     phosphatases and a variety of proteins...; Region: RHOD;
                     cd00158"
                     /db_xref="CDD:238089"
     misc_feature    943071..943073
                     /locus_tag="COSY_0905"
                     /note="active site residue [active]"
                     /db_xref="CDD:238089"
     gene            943209..943838
                     /locus_tag="COSY_0906"
                     /db_xref="GeneID:5171940"
     CDS             943209..943838
                     /locus_tag="COSY_0906"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219734.1"
                     /db_xref="GI:148245040"
                     /db_xref="GeneID:5171940"
                     /translation="MRVKSTWHKTQVKTIDDIASTLAFNSWRITKNHLEDLINEAFII
                     EKAQVFDVISEYLYFLIQCIDRLVLDKLNYKQRQTLIIKLAKQSATYFHENKQERIGS
                     GEYWNDFIQTYNNRSKNYANYEFTNGEPSYHFLRYFAKKIQKAMTNADSKWIVQQIIE
                     IQAPKAFKSIKRSIKNLIAVEKIIFKAEQIKNKNKIPRSKRKSIFPKLQ"
     gene            943888..944310
                     /gene="trxC"
                     /locus_tag="COSY_0907"
                     /db_xref="GeneID:5171905"
     CDS             943888..944310
                     /gene="trxC"
                     /locus_tag="COSY_0907"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="YP_001219735.1"
                     /db_xref="GI:148245041"
                     /db_xref="GeneID:5171905"
                     /translation="MIAICLNCNRLNNIPKNKLKNKPNCGNCKNPIYSGQPINVSGIQ
                     LTRAIEKTDELLVVDFWATWCGPCKTFAPTFKQVTTQLEPKARFIKIETEKEQVISTK
                     HNIRSIPTLAIFKDGKEIERISGSLSAPDFINWVNQYT"
     misc_feature    944038..944298
                     /gene="trxC"
                     /locus_tag="COSY_0907"
                     /note="TRX family; composed of two groups: Group I, which
                     includes proteins that exclusively encode a TRX domain;
                     and Group II, which are composed of fusion proteins of TRX
                     and additional domains. Group I TRX is a small ancient
                     protein that alter the redox...; Region: TRX_family;
                     cd02947"
                     /db_xref="CDD:239245"
     misc_feature    944044..944247
                     /gene="trxC"
                     /locus_tag="COSY_0907"
                     /note="Thioredoxin-like; Region: Thioredoxin_8; pfam13905"
                     /db_xref="CDD:222448"
     misc_feature    order(944080..944082,944089..944091)
                     /gene="trxC"
                     /locus_tag="COSY_0907"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239245"
     gene            complement(944354..944477)
                     /locus_tag="COSY_0907a"
                     /db_xref="GeneID:5236318"
     rRNA            complement(944354..944477)
                     /locus_tag="COSY_0907a"
                     /product="5S ribosomal RNA"
                     /db_xref="GeneID:5236318"
     gene            complement(944655..947560)
                     /locus_tag="COSY_0907b"
                     /db_xref="GeneID:5236319"
     rRNA            complement(944655..947560)
                     /locus_tag="COSY_0907b"
                     /product="23S ribosomal RNA"
                     /db_xref="GeneID:5236319"
     gene            complement(948022..948097)
                     /locus_tag="COSY_t33"
                     /db_xref="GeneID:5329756"
     tRNA            complement(948022..948097)
                     /locus_tag="COSY_t33"
                     /product="tRNA-Ala"
                     /db_xref="GeneID:5329756"
     gene            complement(948097..948193)
                     /locus_tag="COSY_0907c"
                     /db_xref="GeneID:5236317"
     gene            complement(948193..948269)
                     /locus_tag="COSY_t34"
                     /db_xref="GeneID:5329757"
     tRNA            complement(948193..948269)
                     /locus_tag="COSY_t34"
                     /product="tRNA-Ile"
                     /db_xref="GeneID:5329757"
     gene            complement(948384..949942)
                     /locus_tag="COSY_0907d"
                     /db_xref="GeneID:5236320"
     rRNA            complement(948384..949942)
                     /locus_tag="COSY_0907d"
                     /product="16S ribosomal RNA"
                     /db_xref="GeneID:5236320"
     gene            complement(950273..950752)
                     /locus_tag="COSY_0913"
                     /db_xref="GeneID:5171848"
     CDS             complement(950273..950752)
                     /locus_tag="COSY_0913"
                     /note="Rhodanese is a sulphurtransferase involved in
                     cyanide detoxification."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese family protein"
                     /protein_id="YP_001219736.1"
                     /db_xref="GI:148245042"
                     /db_xref="GeneID:5171848"
                     /translation="MDRYQKLVAQALSSVIEIFSWDLEEEIQRNKDLILLDIREQDEF
                     DMMHIKNSIHVPRGILESACVWNYDNTVPKLVQAINQDIIVICHSGNRSALATLTMQQ
                     MGFNKVRSLKMGIKGWNDNDLEMVNSNHVIVDINKADAWLNRAISEDKLESRKNNAN"
     misc_feature    complement(950399..950677)
                     /locus_tag="COSY_0913"
                     /note="Rhodanese Homology Domain (RHOD); an alpha beta
                     fold domain found duplicated in the rhodanese protein. The
                     cysteine containing enzymatically active version of the
                     domain is also found in the Cdc25 class of protein
                     phosphatases and a variety of proteins...; Region: RHOD;
                     cd00158"
                     /db_xref="CDD:238089"
     misc_feature    complement(950492..950494)
                     /locus_tag="COSY_0913"
                     /note="active site residue [active]"
                     /db_xref="CDD:238089"
     gene            complement(950758..951387)
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /db_xref="GeneID:5171845"
     CDS             complement(950758..951387)
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system, nitrate/nitrite response
                     regulator"
                     /protein_id="YP_001219737.1"
                     /db_xref="GI:148245043"
                     /db_xref="GeneID:5171845"
                     /translation="MKIYIIDDHALFRNGLIALLESKQISASAAASPKQGLIEIPSLS
                     VDIILLDLRMPQMSGLEVLKILKTKNITIPIVMLTTSTQEYDLRSCLKHGAQGYLLKD
                     MDPDELVDALDEVIKGSIVVAQDMRYILAKALRDELTDNEPSFGSLTSREKEVACQVS
                     SGYSNKVIARELGISDGTVKLHVKSILKKLSLSSRVEVAVMVTQKGYCK"
     misc_feature    complement(950776..951381)
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /note="transcriptional regulator NarL; Provisional;
                     Region: PRK10651"
                     /db_xref="CDD:182619"
     misc_feature    complement(951040..951375)
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(951082..951087,951094..951096,
                     951151..951153,951211..951213,951235..951237,
                     951364..951369))
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(951235..951237)
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(951211..951219,951223..951228))
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(951079..951087)
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(950782..950946)
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(950803..950805,950836..950850,
                     950854..950859,950863..950868,950890..950898,
                     950935..950943))
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(950788..950790,950797..950805,
                     950896..950898,950902..950904,950908..950910))
                     /gene="narL"
                     /locus_tag="COSY_0914"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(951384..952868)
                     /gene="narX"
                     /locus_tag="COSY_0915"
                     /db_xref="GeneID:5171973"
     CDS             complement(951384..952868)
                     /gene="narX"
                     /locus_tag="COSY_0915"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system, nitrate/nitrite sensor
                     histidine kinase"
                     /protein_id="YP_001219738.1"
                     /db_xref="GI:148245044"
                     /db_xref="GeneID:5171973"
                     /translation="MNIKTKFYIYFLVTILLSPLLMYEAMLSYTMTSVVDILLVVLIL
                     LVYLGLYLSIRQDFLLPFNDLQSWVDGYKFSQSVRLSDHQKTTFQPVAKAINHLINEN
                     QCLYDDMESILNKQVQRLSKKSASLETLYSVSSKLNKIHSIDELFAHFLDILIKMTGA
                     SSGAARSLSDDSQLHLMATQGVIDKKGQVMDVLSADCFCGEVAMASDTCVQFSVHTCA
                     QCVGKKSRTKASIGTIFIPLRYHGKTLGTFNLFFDTLPSLAFDERVLLSSIAENIAIS
                     LDKAWLDIQTKRMELSQERLFLSQEIHDSLAQTIYSLKLQVTALGNILKVGKKSDAND
                     KVLSLQSNITQANQELRELMCNFRIPLDPKGIKASLTTLLNRFMSEEGITTYLQVEGK
                     LQVSPEVEMQIMRITQEALSNIRKHAKARNVRVLLLAEPNCQLLIEDDGVGFEKDQNK
                     SEVMGNNIGMNIMKERAIRIGANIKIESEVDGSTRVIVNFQKVS"
     misc_feature    complement(951999..952490)
                     /gene="narX"
                     /locus_tag="COSY_0915"
                     /note="FOG: GAF domain [Signal transduction mechanisms];
                     Region: FhlA; COG2203"
                     /db_xref="CDD:225113"
     misc_feature    complement(952032..952445)
                     /gene="narX"
                     /locus_tag="COSY_0915"
                     /note="GAF domain; Region: GAF_3; pfam13492"
                     /db_xref="CDD:222174"
     misc_feature    complement(951399..>952130)
                     /gene="narX"
                     /locus_tag="COSY_0915"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: COG4585"
                     /db_xref="CDD:226951"
     misc_feature    complement(951795..951989)
                     /gene="narX"
                     /locus_tag="COSY_0915"
                     /note="Histidine kinase; Region: HisKA_3; pfam07730"
                     /db_xref="CDD:219540"
     misc_feature    complement(951399..951662)
                     /gene="narX"
                     /locus_tag="COSY_0915"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(951411..951413,951417..951422,
                     951435..951437,951441..951443,951489..951500,
                     951537..951542,951546..951548,951552..951554,
                     951558..951560,951621..951623,951630..951632,
                     951642..951644))
                     /gene="narX"
                     /locus_tag="COSY_0915"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(951630..951632)
                     /gene="narX"
                     /locus_tag="COSY_0915"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(951492..951494,951498..951500,
                     951540..951542,951546..951548))
                     /gene="narX"
                     /locus_tag="COSY_0915"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            complement(952909..954252)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /db_xref="GeneID:5172528"
     CDS             complement(952909..954252)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="in Escherichia coli this protein is involved in the
                     biosynthesis of the hypermodified nucleoside
                     5-methylaminomethyl-2-thiouridine, which is found in the
                     wobble position of some tRNAs and affects ribosomal
                     frameshifting; shows potassium-dependent dimerization and
                     GTP hydrolysis; also involved in regulation of
                     glutamate-dependent acid resistance and activation of
                     gadE"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA modification GTPase TrmE"
                     /protein_id="YP_001219739.1"
                     /db_xref="GI:148245045"
                     /db_xref="GeneID:5172528"
                     /translation="MNSSKTTICALASSVGKGGIGIVRVSGPLCKVIAKKMLGFIPKP
                     RYAYYGLFFDQESTEIDKGIALFFPKPYSFTGEDVLEFQGHGGMIGMRLLLESAISMG
                     AKLAESGEFSKRSFLNGKMDLVQAEAISDMINANSKRASKSAFRSLSGDFSNQINGLT
                     KSIIELRVFVEATIDFSDEEIDFLQFDQVKCKIKDIKQTIETILKSATQGIILREGLN
                     VAIAGKPNAGKSSLLNALTQESSAIVTDIAGTTRDVLKETIHVNGVPLSIIDTAGLRN
                     SHDKIEKEGIKRANFEIEHADVVLMVFDAQDDKPDLSILPKNINDQSLLLIKNKVDLT
                     SGAIKREVINDIVQLSVSAKYSEGIKLLRKELSNISGLEDLSEGVVLARRRHIIALEA
                     SLVSIGNAIMQLEIGAIELMAEDLRFAGQFMGSITGEFSSDDLLDEIFSSFCIGK"
     misc_feature    complement(952912..954234)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="tRNA modification GTPase TrmE; Reviewed; Region:
                     trmE; PRK05291"
                     /db_xref="CDD:235392"
     misc_feature    complement(953893..954234)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="GTP-binding protein TrmE N-terminus; Region:
                     TrmE_N; pfam10396"
                     /db_xref="CDD:204472"
     misc_feature    complement(953431..>953802)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="Circularly permuted YlqF-related GTPases; Region:
                     YlqF_related_GTPase; cl17249"
                     /db_xref="CDD:247803"
     misc_feature    complement(order(953434..953436,953560..953580,
                     953632..953637,953725..953730,953734..953736))
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206746"
     misc_feature    complement(order(953728..953733,953734..953736))
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="G4 box; other site"
                     /db_xref="CDD:206746"
     misc_feature    complement(953629..953637)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="G5 box; other site"
                     /db_xref="CDD:206746"
     misc_feature    complement(953146..953613)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="trmE is a tRNA modification GTPase; Region: trmE;
                     cd04164"
                     /db_xref="CDD:206727"
     misc_feature    complement(953563..953586)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="G1 box; other site"
                     /db_xref="CDD:206727"
     misc_feature    complement(953563..953586)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="G1 box; other site"
                     /db_xref="CDD:206746"
     misc_feature    complement(order(953191..953199,953257..953259,
                     953263..953268,953560..953571,953575..953577))
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206727"
     misc_feature    complement(953491..953541)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206727"
     misc_feature    complement(953488..953511)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206746"
     misc_feature    complement(953500..953502)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="G2 box; other site"
                     /db_xref="CDD:206727"
     misc_feature    complement(953500..953502)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="G2 box; other site"
                     /db_xref="CDD:206746"
     misc_feature    complement(order(953368..953412,953416..953448))
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206727"
     misc_feature    complement(953434..953445)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="G3 box; other site"
                     /db_xref="CDD:206727"
     misc_feature    complement(953434..953445)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="G3 box; other site"
                     /db_xref="CDD:206746"
     misc_feature    complement(953431..953439)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206746"
     misc_feature    complement(953257..953268)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="G4 box; other site"
                     /db_xref="CDD:206727"
     misc_feature    complement(953191..953199)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="G5 box; other site"
                     /db_xref="CDD:206727"
     misc_feature    complement(952921..953127)
                     /gene="trmE"
                     /locus_tag="COSY_0916"
                     /note="Catalytic cysteine-containing C-terminus of GTPase,
                     MnmE; Region: GTPase_Cys_C; pfam12631"
                     /db_xref="CDD:204989"
     gene            complement(954252..955814)
                     /gene="gshA"
                     /locus_tag="COSY_0917"
                     /db_xref="GeneID:5172257"
     CDS             complement(954252..955814)
                     /gene="gshA"
                     /locus_tag="COSY_0917"
                     /EC_number="6.3.2.2"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="YP_001219740.1"
                     /db_xref="GI:148245046"
                     /db_xref="GeneID:5172257"
                     /translation="MQLKEKIQRLKPFDTLLKGNLMGLEKEGLRVSRKGGISQVPHPY
                     ALGCALTHPNITTDFSESLLELVTPPLSGAVEMLSFLENTQYYLYHHLPKDQNFWPTS
                     MPCVIRGETTIPIAQYGTSNQGKLKTIYRQGLANRYGSVMQTIAGIHFNYSFSNKFWQ
                     QYKRLFAPTEVLRSFIDNGYMGLIRNIVRYGWIIPYLFGASPAVCKSFLKGYHTHSLV
                     EFNDSTLYEPYATSLRMGNIGYQNLAEDEAGVKANYNSLSHYINSLKVGMQTSCSEYE
                     MIGVKRHGKYQQLNTNILQIENEYYASVRPKPLLESNKNSLNTLSNSGIGYVELRSID
                     INPLLSLGIDKPQIHFLEAFMLFCLLEPSCAISTSEQFGIDTNDQLVAHEGRKPKLML
                     MYKGKQISRQEWGSDIITKMEWCTALLSENHQVSVRDIACRINNPDLTPSAITLSQMK
                     RRNQGFFDYTNSLSKKYRGDFLFNKINKKHFDYLDHQAKVSCQKQLQIEASDLVDFDT
                     FLNEYFIKYLKN"
     misc_feature    complement(954258..955802)
                     /gene="gshA"
                     /locus_tag="COSY_0917"
                     /note="Glutamate-cysteine ligase; Region: Glu_cys_ligase;
                     cl17352"
                     /db_xref="CDD:247906"
     gene            956171..956785
                     /locus_tag="COSY_0918"
                     /db_xref="GeneID:5171857"
     CDS             956171..956785
                     /locus_tag="COSY_0918"
                     /note="Similar to the C-terminal region of mutator protein
                     MutT (314 aa) in Pseudomonas putida F1,
                     7,8-dihydro-8-oxoguanine-triphosphatase."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219741.1"
                     /db_xref="GI:148245047"
                     /db_xref="GeneID:5171857"
                     /translation="MILNKQLDDYKLLPVMKTFINSIALPDKYWITPSNNHQSNKWME
                     KFNQKLTQNIKLIQLRSKTKINNNFIQQLHNKCKQHNIQLLLNTVNKTFNEAYCDGWN
                     LTTAEMLKFKKRPCTNNKLLGVSTHNLTEALKAQIIGADFVIISPVQATKTHPKLLPL
                     GWDNAKEVVNTLNIPVYFLGGMRLQDLKKTQQLGAQGIAGVSTF"
     misc_feature    956255..956776
                     /locus_tag="COSY_0918"
                     /note="Thiamine monophosphate synthase (TMP
                     synthase)/TenI. TMP synthase catalyzes an important step
                     in the thiamine biosynthesis pathway, the substitution of
                     the pyrophosphate of 2-methyl-4-amino-5-
                     hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-;
                     Region: TMP_TenI; cd00564"
                     /db_xref="CDD:238317"
     misc_feature    order(956255..956257,956261..956263,956342..956344,
                     956348..956350,956543..956545,956594..956596,
                     956600..956602,956621..956623,956627..956629,
                     956699..956701,956711..956713,956765..956776)
                     /locus_tag="COSY_0918"
                     /note="thiamine phosphate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238317"
     misc_feature    order(956342..956344,956348..956350,956354..956356,
                     956429..956431,956477..956479,956543..956545,
                     956621..956623,956627..956632,956711..956713,
                     956771..956776)
                     /locus_tag="COSY_0918"
                     /note="active site"
                     /db_xref="CDD:238317"
     misc_feature    order(956348..956350,956354..956356,956429..956431,
                     956477..956479,956543..956545,956630..956632)
                     /locus_tag="COSY_0918"
                     /note="pyrophosphate binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238317"
     gene            957234..961754
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /db_xref="GeneID:5171858"
     CDS             957234..961754
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /EC_number="1.4.1.13"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase (NADPH) large chain"
                     /protein_id="YP_001219742.1"
                     /db_xref="GI:148245048"
                     /db_xref="GeneID:5171858"
                     /translation="MKTQLLHLPKARGLYHPNNEKENCGIGFIAHIKGKPSHQITIDA
                     LEMLSRMEHRGGCGCETNTGDGAGILTNIPHKFFIQEIKRLFDVVVEKGAYSVGNIFL
                     PQDKKQRAHCMNLLEKSIVCENQTFIGWRNVPININKANIGNIARKSKPVIKQLIIAR
                     AKGIDTPTFERALFIIRKHTSNIIRTDKALSQALLFYVCSMSSNIIIYKGMLLGSQVL
                     DFYQDLSDIKYSTYLAMVHSRFSTNTFPSWDRAQPCRYMSHNGEINTRQGNYNWMHAR
                     EGVLKSKLFKNNLNKTLPVIETEVSDSGSFDNVLEFLMMNGRTLQESALMMVPEAWQN
                     DSNMSAEKKAFYEYLSNIMEPWDGPASIAFTDGFYIGAMLDRNGLRPSRYYLTHDERV
                     IMASEVGVVDVATDNIKTKGRLRPGKMFLVDFNKGELVNDETIKSEFAAKNPYQTWLN
                     IQQIHLSEFHCQTEAHSLHPESLIHRLKTFGYSTETLQFMLLPLVNELRDPVGSMGND
                     SALACLSSQSRIIYDYFKQLFAQVTNPAIDSIREEVVMSLRCSIGPEGNLLHDKAENA
                     HRLVIEHPILTNKEVTALKHCNHRNWTSKTIDITYDINKGKKISDLLDDICNQGSQAI
                     KNKHNLIILSDRNIDKNRVAISSLLASSALHRHLVASTERTQVGIIVETGEAREVHHF
                     CLMIGFGADAINPYLAFEALWQARRDEIIDIKSDDAIISSYRKSIAKGMLKVMAKMGI
                     STLESYKGAQIFEAVGLAPEIMDKCFFGTASRINGVNFDILQTESEKRHQNAYQTNSL
                     DNFGQYYWRSGGEKHMWDPQTISHLQNAARNNNKSAYWAFSKHANEQGTRNSTLRGLM
                     SFKKGNPINIDDVENIKKIVKRFATGAMSFGSISSESHESLAIAMNRLGGKSNTGEGG
                     EDKKRWTPDINGDSRRSAIKQVASGRFGVTIDYLNNADEIQIKVSQGAKPGEGGELPG
                     TKVDENIASIRHSTPGVGLISPPPHHDIYSIEDLSQLIFDLKRSNPSARISVKLVAEV
                     GVGTIAAGVVKAKSDHIVIAGHDGGTGASPLTSIKHAGLPWELGLAETHQTLVMNGLR
                     SRIVVQIDGQLKTGRDVAIGILLGAEEFGFSTAPLITLGCIMMRKCHLNTCPVGIATQ
                     DIELRKKFTGKPEHVVNYLFMVAQELRLIMAELGFKTVNEMIGRVDMLQMNQILNHWK
                     QGTINLDALLTPAKKPNKHTDTYQTVTQDHQLNQQIDNKLIAKSKLAVKNTEKVYINS
                     IITNVDRAVGTMLSSYIVKTRGTNNLQDDTIHINFKGSAGQSLGAFLAKGVTLEVEGD
                     ANDYVGKGISGGCIIVYPPKNSTFNAENEIIAGNVCGYGATAGEIYLSGCVSERFCVR
                     NSGAIAVAEGVGDHGCEYMTGGRAIILGEVGRNFGAGMSGGIAYIYNPHHTFESMANP
                     IMIDLDPMDSETQIELKQYINNHAKYTGSKIATRILDNWHSEIKHFIKIMPKDFKRVL
                     AKKITSNQFQQK"
     misc_feature    957264..961697
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="glutamate synthase subunit alpha; Provisional;
                     Region: gltB; PRK11750"
                     /db_xref="CDD:236968"
     misc_feature    957303..958562
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="Glutamine amidotransferases class-II (Gn-AT),
                     glutamate synthase (GltS)-type. GltS is a homodimer that
                     synthesizes L-glutamate from 2-oxoglutarate and
                     L-glutamine, an important step in ammonia assimilation in
                     bacteria, cyanobacteria and plants. The...; Region: GltS;
                     cd00713"
                     /db_xref="CDD:238365"
     misc_feature    order(957303..957305,957393..957395,957948..957950,
                     958011..958019,958137..958139)
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="active site"
                     /db_xref="CDD:238365"
     misc_feature    order(957561..957563,957570..957572,957582..957584,
                     957621..957623,957627..957629,957642..957644,
                     957681..957683,957693..957695,957966..957968)
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238365"
     misc_feature    958650..959504
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="Glutamate synthase central domain; Region:
                     Glu_syn_central; pfam04898"
                     /db_xref="CDD:218318"
     misc_feature    959676..960818
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="Glutamate synthase (GltS) FMN-binding domain.  GltS
                     is a complex iron-sulfur flavoprotein that catalyzes the
                     reductive synthesis of L-glutamate from 2-oxoglutarate and
                     L-glutamine via intramolecular channelling of ammonia, a
                     reaction in the plant, yeast...; Region: GltS_FMN;
                     cd02808"
                     /db_xref="CDD:239202"
     misc_feature    order(959877..959888,959967..959969,960036..960038,
                     960102..960104,960120..960122,960180..960182,
                     960306..960308,960396..960404,960519..960521,
                     960525..960527,960588..960593,960615..960617,
                     960633..960635,960648..960650)
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="active site"
                     /db_xref="CDD:239202"
     misc_feature    order(959877..959888,959967..959969,960036..960038,
                     960102..960104,960306..960308,960396..960401,
                     960519..960521,960525..960527,960588..960593)
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="FMN binding site [chemical binding]; other site"
                     /db_xref="CDD:239202"
     misc_feature    order(960120..960122,960180..960182,960399..960404)
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239202"
     misc_feature    order(960615..960617,960633..960635,960648..960650)
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="3Fe-4S cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239202"
     misc_feature    960951..961697
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="gltb_C. This domain is found at the C-terminus of
                     the large subunit (gltB) of glutamate synthase (GltS).
                     GltS encodes a complex iron-sulfur flavoprotein that
                     catalyzes the synthesis of L-glutamate from L-glutamine
                     and 2-oxoglutarate. It requires the...; Region: gltB_C;
                     cd00982"
                     /db_xref="CDD:238482"
     misc_feature    order(961050..961055,961062..961064,961071..961076,
                     961131..961133,961140..961145,961155..961157,
                     961191..961199,961212..961214,961221..961223,
                     961278..961289,961296..961298,961305..961307,
                     961314..961316,961341..961355,961362..961367,
                     961371..961373,961398..961409,961416..961421,
                     961425..961427,961464..961466,961473..961475,
                     961482..961484,961527..961538)
                     /gene="gltB"
                     /locus_tag="COSY_0919"
                     /note="domain interface; other site"
                     /db_xref="CDD:238482"
     gene            complement(961807..962298)
                     /gene="folA"
                     /locus_tag="COSY_0920"
                     /db_xref="GeneID:5172597"
     CDS             complement(961807..962298)
                     /gene="folA"
                     /locus_tag="COSY_0920"
                     /EC_number="1.5.1.3"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="YP_001219743.1"
                     /db_xref="GI:148245049"
                     /db_xref="GeneID:5172597"
                     /translation="MKLSIIVAMDDNYLIGKDNSLPWYLPADLAYFKKITIGKTILMG
                     RKTHDSIGRSLPNRRNIIVSKNTKFKADNCEVVSSIDVALSLANNDNELMIVGGSSFY
                     DQIIDKVDRLYITEVKGMFDGDAYFPEFDRTKFIELSRESHKPDEKNFYTYNFIVLQR
                     NTY"
     misc_feature    complement(961816..962295)
                     /gene="folA"
                     /locus_tag="COSY_0920"
                     /note="Dihydrofolate reductase [Coenzyme metabolism];
                     Region: FolA; COG0262"
                     /db_xref="CDD:223340"
     misc_feature    complement(961822..962292)
                     /gene="folA"
                     /locus_tag="COSY_0920"
                     /note="Dihydrofolate reductase (DHFR). Reduces
                     7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH
                     as a cofactor. This is an essential step in the
                     biosynthesis of deoxythymidine phosphate since
                     5,6,7,8-tetrahydrofolate is required to regenerate 5;
                     Region: DHFR; cd00209"
                     /db_xref="CDD:238127"
     misc_feature    complement(order(961954..961956,961993..961995,
                     962011..962013,962125..962127,962215..962217,
                     962230..962232,962281..962283))
                     /gene="folA"
                     /locus_tag="COSY_0920"
                     /note="folate binding site [chemical binding]; other site"
                     /db_xref="CDD:238127"
     misc_feature    complement(order(961999..962010,962104..962106,
                     962158..962166,962254..962256,962275..962277))
                     /gene="folA"
                     /locus_tag="COSY_0920"
                     /note="NADP+ binding site [chemical binding]; other site"
                     /db_xref="CDD:238127"
     gene            962354..962959
                     /gene="maf"
                     /locus_tag="COSY_0921"
                     /db_xref="GeneID:5171980"
     CDS             962354..962959
                     /gene="maf"
                     /locus_tag="COSY_0921"
                     /note="nucleotide-binding protein implicated in inhibition
                     of septum formation."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation protein Maf"
                     /protein_id="YP_001219744.1"
                     /db_xref="GI:148245050"
                     /db_xref="GeneID:5171980"
                     /translation="MISLILASNSPFRKTLLAKLGLAFDTHPPKIDESRKKGETPEKL
                     VYRLAQEKAREIGKTHSGLIIASDQVATINNGFNNDDNILTKPKNHKEAIKQLQQNSC
                     NTVNFLTSLSLLNTNTGNMQTKVEIFKVIFKKLNIDQINHYLKKETPYNCAGSFKSES
                     LGIGLFKCMIGNDPNSLIGLPLIQLITMLENEGIDILTDNI"
     misc_feature    962363..962935
                     /gene="maf"
                     /locus_tag="COSY_0921"
                     /note="Maf-like protein; Region: Maf; pfam02545"
                     /db_xref="CDD:202278"
     misc_feature    962363..962920
                     /gene="maf"
                     /locus_tag="COSY_0921"
                     /note="Nucleotide binding protein Maf. Maf has been
                     implicated in inhibition of septum formation in
                     eukaryotes, bacteria and archaea, but homologs in
                     B.subtilis and S.cerevisiae are nonessential for cell
                     division. Maf has been predicted to be a nucleotide-
                     or...; Region: Maf; cd00555"
                     /db_xref="CDD:238310"
     misc_feature    order(962375..962377,962390..962392,962450..962452,
                     962507..962509,962555..962557,962609..962611)
                     /gene="maf"
                     /locus_tag="COSY_0921"
                     /note="active site"
                     /db_xref="CDD:238310"
     misc_feature    order(962489..962491,962711..962728)
                     /gene="maf"
                     /locus_tag="COSY_0921"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238310"
     gene            962962..966399
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /db_xref="GeneID:5172542"
     CDS             962962..966399
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /note="superfamily II helicase"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="YP_001219745.1"
                     /db_xref="GI:148245051"
                     /db_xref="GeneID:5172542"
                     /translation="MMPYLYSNKVKCFELGRKMYWGSLYGSADALALIEFANQQHIIL
                     VIANDIVHFDNFYKSLKFYNTDLEILKFDNWEVLAYDYFSPHPDITSSRLKTLSKLKS
                     LKRGIVITTLESLFSHLCPLEFSKKYSLNIRINDKINPDTFSEKLLKIGYKHVITVME
                     HGEFNMRNSLIDLYPMGTKTAYRINLFNQKVESIRAFNTSTQRSKTKIPEITLLPARE
                     FATDNTSIEYFKTNYKKIFNDNGFIYTEVSEGRLPGGIEFYLPLFFHTTNTLFDYLAD
                     NTIIATSKEFSNLVDKTYNEIRERFENAKKSLDRAPLDIQRVFLSKELLFSEVKKKSQ
                     IIISTSKLENKKQHFNFNSSLPPPVRIELQTNNPLSKFSTFVKRFTNKQNKKILIVCE
                     SLDRQNVLSDLLINHNLNTYSVKSWHEFTTSSKSLNIIHEDLIHGLLIHNIAIITEED
                     LFGQEVVQQQRRHTKHKYFDVAIKSLVEIKIGDAIVHENYGVGRYLGLKTKIFDKQSQ
                     DFLVLKYANNAKLMVPIISFNLISRYAGISLKSTPLHKLGTNQWAKAKKKAGEALFDI
                     AVELLKISAKRSSQTGFSFPKPNDDYSSFVANFPFEETPDQIKTMNEVLADMQSQQPM
                     DRLVCGDVGFGKTEIAMRAAFLAVKAGKQVAILVPTTLLSNQHYRSFIDRFTNDPTKI
                     ATLSRFQTPKEQKIIIEQLKQGTIDIIIGTHKIIQNNIKYKNLSLIIIDEEHRFGVKQ
                     KEALKKLRGQSDILTMTATPIPRTLNMALGSLRELSIIATPPAKRSTIQTFVQEWHND
                     NIKEAITREIHRGGQVFILHNDINSIDNMAENLKQIIPKLQIRIAHGKIPTRELEQIM
                     SDFYHARFHILVCTTIIETGIDIPNANTIIINNAQNFGLAQLHQLRGRVGRSHHRAYA
                     YLIVKSHLSLSKTAKDRLDVIKSLTELGSGFMLANHDLEIRGAGDLLGDNQSGQISEI
                     GFNLYHDLLKRTIDAVYSGKKINLNDPINHEVQIDSGLPSIIPETYIFDVHERLVLYK
                     RIANCQNNNELKALQIEMIDRFGLLPDSTKNLLYNTKLKLFSQIIGVNKIILYEDKAI
                     ITFNKKNTIDPIKITNLIQKQAKKYQLKDQNQLIIKEQMPKNIRRIKLIEYLLKMLN"
     misc_feature    963007..966393
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /note="Transcription-repair coupling factor (superfamily
                     II helicase) [DNA replication, recombination, and repair /
                     Transcription]; Region: Mfd; COG1197"
                     /db_xref="CDD:224118"
     misc_feature    964393..964680
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /note="CarD-like/TRCF domain; Region: CarD_TRCF;
                     smart01058"
                     /db_xref="CDD:215001"
     misc_feature    964831..965241
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /note="DEAD-like helicases superfamily. A diverse family
                     of proteins involved in ATP-dependent RNA or DNA
                     unwinding. This domain contains the ATP-binding region;
                     Region: DEXDc; cd00046"
                     /db_xref="CDD:238005"
     misc_feature    964858..964872
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238005"
     misc_feature    965152..965163
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /note="putative Mg++ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238005"
     misc_feature    965332..965712
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:238034"
     misc_feature    order(965416..965427,965491..965496,965569..965577)
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:238034"
     misc_feature    order(965596..965598,965659..965661,965671..965673,
                     965680..965682)
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238034"
     misc_feature    965980..966279
                     /gene="mfd"
                     /locus_tag="COSY_0922"
                     /note="This domain is found in proteins necessary for
                     strand-specific repair in DNA such as TRCF in Escherichia
                     coli; Region: TRCF; smart00982"
                     /db_xref="CDD:198050"
     gene            complement(966414..967355)
                     /locus_tag="COSY_0923"
                     /db_xref="GeneID:5172082"
     CDS             complement(966414..967355)
                     /locus_tag="COSY_0923"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="YP_001219746.1"
                     /db_xref="GI:148245052"
                     /db_xref="GeneID:5172082"
                     /translation="MTKTALICGSYAFDSIMVFHDYFNNHILPDRVHMLNVSFLVPTM
                     RKEFGGCAGNIAYNLHLLGVNSVPMATVGSDFTPYLEWMTRCHMNTAYIKIIPGQYTG
                     QAFITTDMSGNQITVFHPGAMDQSHQNKVFDVSMVDIGIVSPDGRTGMIEHAAQFKQL
                     NIPFIFDPGQGMPMFSGEELINFIEQASYVVVNSYESQMLQDRTGLNLATIAIKVKAL
                     FITKGIQGSEIHTEEKVINITPVKVDVFQDPTGCGDAYRAGLLYGLMNGMDWKTIGQL
                     AGLLGAIKVTHLGAQNHQFDMGYIEKYYQDNYGELLF"
     misc_feature    complement(966483..967346)
                     /locus_tag="COSY_0923"
                     /note="Ribokinase-like subgroup A.  Found in bacteria and
                     archaea, this subgroup is part of the ribokinase/pfkB
                     superfamily.  Its oligomerization state is unknown at this
                     time; Region: ribokinase_group_A; cd01942"
                     /db_xref="CDD:238917"
     misc_feature    complement(966483..967340)
                     /locus_tag="COSY_0923"
                     /note="Sugar kinases, ribokinase family [Carbohydrate
                     transport and metabolism]; Region: RbsK; COG0524"
                     /db_xref="CDD:223598"
     misc_feature    complement(order(966594..966596,966603..966605,
                     967194..967196))
                     /locus_tag="COSY_0923"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238917"
     misc_feature    complement(order(966513..966515,966522..966524,
                     966588..966590,966597..966602,966609..966611,
                     966693..966695,966777..966779))
                     /locus_tag="COSY_0923"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238917"
     gene            complement(967424..968350)
                     /gene="ispH"
                     /locus_tag="COSY_0924"
                     /db_xref="GeneID:5171969"
     CDS             complement(967424..968350)
                     /gene="ispH"
                     /locus_tag="COSY_0924"
                     /EC_number="1.17.1.2"
                     /note="catalyzes the conversion of
                     1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into
                     isopentenyl diphosphate (IPP) and dimethylallyl
                     diphosphate (DMAPP); functions in the nonmevalonate
                     isoprenoid biosynthesis pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="YP_001219747.1"
                     /db_xref="GI:148245053"
                     /db_xref="GeneID:5171969"
                     /translation="MKVLLANPRGFCAGVDRAIEIVECALKLHGAPVYVRHEVVHNKF
                     VVDGLKNKGAVFVEDIADVPNNQVVIFSAHGVSIAVRRQTHNIGAIIYDATCPLVTKV
                     HKEVARKQKQNYQVILIGHKGHPEVEGTLGQSSESNCVQLVETIEDVERLNLSKNMSF
                     SYTTQTTLSIDDTQSIIDYLKLRIPTIDMPKKDDICYATQNRQDAVKILMQFSSVLLI
                     LGSSNSSNSNRLREIAEKIGIPAYLIDGIDNIDELWFKGVDTIGVTAGASAPEVLVQE
                     VVHYLRDKGATKVIEVGGVKENIHFPVPKELR"
     misc_feature    complement(967451..968350)
                     /gene="ispH"
                     /locus_tag="COSY_0924"
                     /note="4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
                     Reviewed; Region: ispH; PRK01045"
                     /db_xref="CDD:234893"
     misc_feature    complement(967469..968350)
                     /gene="ispH"
                     /locus_tag="COSY_0924"
                     /note="4-Hydroxy-3-methylbut-2-enyl diphosphate reductase
                     IspH [Lipid metabolism]; Region: lytB; COG0761"
                     /db_xref="CDD:223832"
     gene            complement(968347..968754)
                     /locus_tag="COSY_0925"
                     /db_xref="GeneID:5172237"
     CDS             complement(968347..968754)
                     /locus_tag="COSY_0925"
                     /EC_number="5.2.1.8"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase 2"
                     /protein_id="YP_001219748.1"
                     /db_xref="GI:148245054"
                     /db_xref="GeneID:5172237"
                     /translation="MTKYKIFYKFSHANGTLIDESWDDPLEFELGDGQLDFCLESCVI
                     DAQVGKLQTFLLSASEAFGNELEEAFQIMKRLDFPQTMMIELDSVVEFKTPIGDSYVG
                     CIDKIKNDDITVNFNHPLAGNDVSFQVKILQKQ"
     misc_feature    complement(968350..968742)
                     /locus_tag="COSY_0925"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerases 2
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: SlpA; COG1047"
                     /db_xref="CDD:223976"
     misc_feature    complement(<968560..968742)
                     /locus_tag="COSY_0925"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase;
                     Region: FKBP_C; pfam00254"
                     /db_xref="CDD:215821"
     gene            complement(968747..969595)
                     /gene="accD"
                     /locus_tag="COSY_0926"
                     /db_xref="GeneID:5171990"
     CDS             complement(968747..969595)
                     /gene="accD"
                     /locus_tag="COSY_0926"
                     /EC_number="6.4.1.2"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit beta"
                     /protein_id="YP_001219749.1"
                     /db_xref="GI:148245055"
                     /db_xref="GeneID:5171990"
                     /translation="MSWLEKILPSITSVVKKDIPKGLWSKCPKCETTLYSEELKTLNY
                     VCPKCDYHIRLTARARIDGFLDKKGQEEVAADLSAVDPLKFKDQKKYKDRYLQAQRIT
                     HEKDALVVKIGTLNGIKVVVVAFEFKFMGGSMGSVVGEKFVRAAKISIKTNTPLICFS
                     ASGGARMQEGLFSLMQMSKTALIIKLLSDKKVPFISILTDPTMGGVSASFAMLGDIHI
                     AEPSALIGFAGPRVVKQTVREALPEGFQRSEFLLDKGAIDMIVHRSELRTQVHRILSA
                     MTFNND"
     misc_feature    complement(968762..969595)
                     /gene="accD"
                     /locus_tag="COSY_0926"
                     /note="acetyl-CoA carboxylase subunit beta; Validated;
                     Region: PRK05654"
                     /db_xref="CDD:235547"
     misc_feature    complement(<968891..969439)
                     /gene="accD"
                     /locus_tag="COSY_0926"
                     /note="malonate decarboxylase subunit beta; Reviewed;
                     Region: PRK07189; cl17682"
                     /db_xref="CDD:248236"
     gene            complement(969615..970412)
                     /gene="trpA"
                     /locus_tag="COSY_0927"
                     /db_xref="GeneID:5172334"
     CDS             complement(969615..970412)
                     /gene="trpA"
                     /locus_tag="COSY_0927"
                     /EC_number="4.2.1.20"
                     /note="catalyzes the formation of indole and
                     glyceraldehyde 3-phosphate from indoleglycerol phosphate
                     in tryptophan biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="YP_001219750.1"
                     /db_xref="GI:148245056"
                     /db_xref="GeneID:5172334"
                     /translation="MSRLSRVFFDSPKNHKVFIPFITAGDSGLDNTFELMQVLVKNGA
                     DVIELGVPFSDPMADGPVISRSYERTVKDGVSLSDVFTVVKKFRQTNNTTAIVLMGYL
                     NPIEVFGYQPFANAASESGVDGVLVVDMPPEEAYGLKQILDGVGINFIFLVAPTTMDE
                     RLVFLATIASGFIYFVSLKGVTGAEYLDINLVKTHILRIRQVIDLPIGVGFGIKDAIS
                     AKIVSEYADAVIVGSSLVGLVERYANDRTKMLAKVGYLANEISTIIK"
     misc_feature    complement(969633..970361)
                     /gene="trpA"
                     /locus_tag="COSY_0927"
                     /note="Ttryptophan synthase (TRPS) alpha subunit (TSA).
                     TPRS is a bifunctional tetrameric enzyme (2 alpha and 2
                     beta subunits) that catalyzes the last two steps of
                     L-tryptophan biosynthesis. Alpha and beta subunit catalyze
                     two distinct reactions which are both...; Region:
                     Tryptophan_synthase_alpha; cd04724"
                     /db_xref="CDD:240075"
     misc_feature    complement(order(969714..969719,969777..969782,
                     969864..969869,969891..969893,970224..970226,
                     970236..970238,970269..970271))
                     /gene="trpA"
                     /locus_tag="COSY_0927"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240075"
     misc_feature    complement(order(969867..969869,970110..970112,
                     970236..970238,970269..970271))
                     /gene="trpA"
                     /locus_tag="COSY_0927"
                     /note="active site"
                     /db_xref="CDD:240075"
     misc_feature    complement(order(970110..970112,970236..970238,
                     970269..970271))
                     /gene="trpA"
                     /locus_tag="COSY_0927"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:240075"
     misc_feature    complement(order(969930..969932,969939..969947,
                     969951..969953,970011..970013,970020..970022,
                     970026..970031,970095..970097,970104..970106,
                     970218..970223,970230..970232,970239..970241,
                     970245..970256))
                     /gene="trpA"
                     /locus_tag="COSY_0927"
                     /note="heterodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240075"
     gene            complement(970414..971451)
                     /gene="hemE"
                     /locus_tag="COSY_0928"
                     /db_xref="GeneID:5172262"
     CDS             complement(970414..971451)
                     /gene="hemE"
                     /locus_tag="COSY_0928"
                     /EC_number="4.1.1.37"
                     /note="catalyzes the formation of coproporphyrinogen from
                     uroporphyrinogen III"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="YP_001219751.1"
                     /db_xref="GI:148245057"
                     /db_xref="GeneID:5172262"
                     /translation="MSFDYINALLKKPTSRTPIWIMRQAGRYLPEYRATRAKAGDFLT
                     LCKSPELACEVTMQPIDRFDLDAAILFSDILTIPDAMGLGLYFMEGEGPKFRNPIKNL
                     KDIKKISTDLNNDLSYVFDGVSTIKKSLNNRVPLIGFSGSPWTLATYMIEGGGRIFAS
                     TKKMLFNDPEALHLLLMKLTKSVIAYLNQQIVSGADSVMVFDTWGGVLSEQNYLDFSL
                     YYMAKIVKGVKAQHPNIPITLFSKNGGKYLTHIANTGCDGVGIDWTVELYQVQQEVGN
                     KVAIQGNLDPAVLYATPEVIEREVKKVLSQFKGDTGYIFNLGHGITPDVDPENVKILV
                     DCVHTFSKECR"
     misc_feature    complement(970438..971436)
                     /gene="hemE"
                     /locus_tag="COSY_0928"
                     /note="Uroporphyrinogen decarboxylase (URO-D) is a dimeric
                     cytosolic enzyme that decarboxylates the four acetate side
                     chains of uroporphyrinogen III (uro-III) to create
                     coproporphyrinogen III, without requiring any prosthetic
                     groups or cofactors. This reaction...; Region: URO-D;
                     cd00717"
                     /db_xref="CDD:238368"
     misc_feature    complement(order(970495..970497,970732..970734,
                     970840..970845,970849..970851,970987..970989,
                     971005..971007,971035..971037,971176..971178,
                     971191..971193,971227..971247,971326..971328,
                     971344..971346,971356..971358,971371..971388))
                     /gene="hemE"
                     /locus_tag="COSY_0928"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238368"
     misc_feature    complement(order(970495..970497,970843..970845,
                     971005..971007,971233..971235,971371..971373,
                     971383..971385))
                     /gene="hemE"
                     /locus_tag="COSY_0928"
                     /note="active site"
                     /db_xref="CDD:238368"
     gene            complement(971537..971749)
                     /gene="rpmE"
                     /locus_tag="COSY_0929"
                     /db_xref="GeneID:5172317"
     CDS             complement(971537..971749)
                     /gene="rpmE"
                     /locus_tag="COSY_0929"
                     /note="RpmE; there appears to be two types of ribosomal
                     proteins L31 in bacterial genomes; some contain a CxxC
                     motif while others do not; Bacillus subtilis has both
                     types; the proteins in this cluster have the CXXC motif;
                     RpmE is found in exponentially growing Bacilli while YtiA
                     was found after exponential growth; expression of ytiA is
                     controlled by a zinc-specific transcriptional repressor;
                     RpmE contains one zinc ion and a CxxC motif is responsible
                     for this binding; forms an RNP particle along with
                     proteins L5, L18, and L25 and 5S rRNA; found crosslinked
                     to L2 and L25 and EF-G; may be near the
                     peptidyltransferase site of the 50S ribosome"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="YP_001219752.1"
                     /db_xref="GI:148245058"
                     /db_xref="GeneID:5172317"
                     /translation="MKTSIHPNYNDVQIICSCGNTFKTRSTIDKKELHLDVCSSCHPF
                     YTGKQKIMDSAGRVEKFKSRYASFKR"
     misc_feature    complement(971540..971749)
                     /gene="rpmE"
                     /locus_tag="COSY_0929"
                     /note="50S ribosomal protein L31; Reviewed; Region: rpmE;
                     PRK00019"
                     /db_xref="CDD:234576"
     gene            complement(971831..974236)
                     /locus_tag="COSY_0930"
                     /db_xref="GeneID:5172409"
     CDS             complement(971831..974236)
                     /locus_tag="COSY_0930"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-transporting P-type ATPase"
                     /protein_id="YP_001219753.1"
                     /db_xref="GI:148245059"
                     /db_xref="GeneID:5172409"
                     /translation="MSNSCYHCGLEVIIRNQVRVPIEGKQQDFCCSGCASVCQTIYLS
                     GLSSFYHQQTNSLLPAIDLEYPIEFYDAQAFQQPFLESSYESGTKTITLISNTIHCAA
                     CVWLIERAINALNGVLWVRVNLTDKRIRLSWVDTDIQLSVIMQKLADLGYSAMPYEQD
                     IAESVANKINRLILYRIGFSAFTMMNLLWISIALYTGATDGKYHHYFQWLSFVLATPT
                     LFYAGMPFLKNAYFGLKNCFMNMDVPISIGALSTYFYSVYVLFGLSAKNEVYFDTVVN
                     FIFVILIGRYLESSAKKSTLSASSALQQLQPKVAYVINKGEEQITPVGIIKIGDTVLI
                     KPAERIAVDGIVLSGNSEVDESLLTGESLLIRKQSSDEVFAGSINASGSLIIKVTKTL
                     RNSALGQIVSLVETTKYNKSSIICMLDKIIPYFVGMTILLAIVTFIYWYPYDFDLALL
                     SATSVLIITCPCAFGLATPMSVAVASGVAIKKKILIKNSDALEVLDKVDWVVFDKTGT
                     LTRGKFSISHIETVIDKTIFINIMRSIERYSEHPLAKAIVDIDFASKYLAVSGFYADY
                     GQGVSGIVDQQRYKIGNLSYVDVHHKVNTDLLNKSIILEEQGASCIWCATESEVLGFV
                     ILQDKIKLDAAKVVNQLTSIGKQVSILSGDSKIVTQAIALELGIEHMISQALPKDKAN
                     YIKQLQQRHIVLMVGDGVNDAPALVQADVSIAIGSGSDVSVNSADLVILESTISPIID
                     LINLAKHTNSIIRQNIIFALLYNTFMIPLAMMSKVTPLFAAIVMPISSLIVIGNAARL
                     RNK"
     misc_feature    complement(973994..974230)
                     /locus_tag="COSY_0930"
                     /note="Putative metal-binding domain of cation transport
                     ATPase; Region: ATPase-cat_bd; pfam12156"
                     /db_xref="CDD:221444"
     misc_feature    complement(971834..973945)
                     /locus_tag="COSY_0930"
                     /note="Cation transport ATPase [Inorganic ion transport
                     and metabolism]; Region: ZntA; COG2217"
                     /db_xref="CDD:225127"
     misc_feature    complement(973775..973945)
                     /locus_tag="COSY_0930"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    complement(order(973928..973930,973937..973945))
                     /locus_tag="COSY_0930"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    complement(972758..973408)
                     /locus_tag="COSY_0930"
                     /note="E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122"
                     /db_xref="CDD:215733"
     misc_feature    complement(972119..972394)
                     /locus_tag="COSY_0930"
                     /note="haloacid dehalogenase-like hydrolase; Region: HAD;
                     pfam12710"
                     /db_xref="CDD:221729"
     gene            974447..975118
                     /locus_tag="COSY_0931"
                     /db_xref="GeneID:5172068"
     CDS             974447..975118
                     /locus_tag="COSY_0931"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219754.1"
                     /db_xref="GI:148245060"
                     /db_xref="GeneID:5172068"
                     /translation="MNKLSIQLIVLLSLLFFSNKSISESPIHLYKQYLIGTPRAYLQK
                     SHPLEDCSAKYEKGTLCMKNHLLAGEKAEIAFRFLNDKLVSIVLIMTLTDVSKIKKIF
                     YVLKTQFDLVLIEDGYNKLDIIQINASTFNKHEFTKIIANFENEAYQKHNIKYTFISK
                     YEFITQSRKSRNFSDIFKNAPMRMRAAIYSIGRKDEQVIGTISFIVPGVTQSYLDQNP
                     IVEDF"
     gene            975128..976477
                     /gene="glmU"
                     /locus_tag="COSY_0932"
                     /db_xref="GeneID:5172101"
     CDS             975128..976477
                     /gene="glmU"
                     /locus_tag="COSY_0932"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /note="bifunctional glucosamine-1-phosphate
                     N-acetyltransferase / UDP-N-acetylglucosamine
                     pyrophosphorylase."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional peptidoglycan biosynthesis protein
                     GlmU"
                     /protein_id="YP_001219755.1"
                     /db_xref="GI:148245061"
                     /db_xref="GeneID:5172101"
                     /translation="MNNIHAIILAAGKGTRMNSTKPKVLQILSNNTLLEHVLSQVKTL
                     CNKIHIAYGFEGKQVQQKINNPSINWVKQVKQLGTGHAVAQVMPYIEGNSISLILYGD
                     VPLIKRSTLYDLINKTQQSGIALLSVILNNPTGYGRIIRNNKQIQAIVEQKDASNMQL
                     NINEVNTGIMAINSQLLKQYLNEIDSRNTQGELYLTDIIACAAADKKTISSIISKNKF
                     EVLGVNDKVQLAELERLFQKDQAIQFMKQGLGLKDPTRFDCRGTLTFGQNCEIDVNTL
                     IKGKVALGNSTTIEPNCIIKNTIIGNHVSIFPNCVIEDAVIGEGVTIGPFVHIRPQTH
                     IQTHAKIGNFVEIKKSTIGKNTKISHLSYVGDSTIGKNVNIGAGVITCNYDGVNKHQT
                     IIADGAFIGSDSQLIAPIKIGKNAKIGAGSTITKSVSENQLSVSRTKQKNLKYRSKK"
     misc_feature    975137..976474
                     /gene="glmU"
                     /locus_tag="COSY_0932"
                     /note="UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase; Region: glmU; TIGR01173"
                     /db_xref="CDD:233299"
     misc_feature    975143..975814
                     /gene="glmU"
                     /locus_tag="COSY_0932"
                     /note="N-terminal domain of bacterial GlmU; Region:
                     GT2_GlmU_N_bac; cd02540"
                     /db_xref="CDD:133020"
     misc_feature    order(975152..975160,975278..975280,975362..975364,
                     975371..975373,975425..975427,975431..975433)
                     /gene="glmU"
                     /locus_tag="COSY_0932"
                     /note="Substrate binding site; other site"
                     /db_xref="CDD:133020"
     misc_feature    order(975431..975433,975797..975799)
                     /gene="glmU"
                     /locus_tag="COSY_0932"
                     /note="Mg++ binding site; other site"
                     /db_xref="CDD:133020"
     misc_feature    975869..976447
                     /gene="glmU"
                     /locus_tag="COSY_0932"
                     /note="N-acetyl-glucosamine-1-phosphate uridyltransferase
                     (GlmU), C-terminal left-handed beta-helix (LbH)
                     acetyltransferase domain: GlmU is also known as
                     UDP-N-acetylglucosamine pyrophosphorylase. It is a
                     bifunctional bacterial enzyme that catalyzes two...;
                     Region: LbH_GlmU_C; cd03353"
                     /db_xref="CDD:100044"
     misc_feature    order(976115..976117,976163..976165,976169..976171,
                     976205..976207,976214..976216,976247..976258,
                     976271..976279,976292..976294,976322..976324,
                     976328..976333,976382..976387,976436..976438)
                     /gene="glmU"
                     /locus_tag="COSY_0932"
                     /note="active site"
                     /db_xref="CDD:100044"
     misc_feature    order(976115..976117,976163..976165,976169..976171,
                     976205..976207,976214..976216,976247..976255,
                     976274..976276,976292..976294)
                     /gene="glmU"
                     /locus_tag="COSY_0932"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100044"
     misc_feature    order(976256..976258,976271..976273,976277..976279,
                     976328..976333,976382..976387,976436..976438)
                     /gene="glmU"
                     /locus_tag="COSY_0932"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:100044"
     gene            complement(977043..978248)
                     /gene="trpB"
                     /locus_tag="COSY_0933"
                     /db_xref="GeneID:5172184"
     CDS             complement(977043..978248)
                     /gene="trpB"
                     /locus_tag="COSY_0933"
                     /EC_number="4.2.1.20"
                     /note="catalyzes the formation of L-tryptophan from
                     L-serine and 1-(indol-3-yl)glycerol 3-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="YP_001219756.1"
                     /db_xref="GI:148245062"
                     /db_xref="GeneID:5172184"
                     /translation="MSNYNLPDDNGHFDKYGGIFIAETLMTAVFELKDAYARFKNDSK
                     FICEFEQDLKHYAGRETPLYYAKNLSKKLRGAQIYLKREDLNHTGSHKINNTIGQALL
                     AKRMGKTRIIAETGAGQHGVATATVAARLGLECVVYMGEVDVARQSLNVFRMKLLGAK
                     VIPVTSGSKTLKDSLNEAMRDWVKNIDDTFYIIGTIAGPHPYPMMVRDFQSIIGKEAK
                     AQFHDQVGGLPDALVACVGGGSNAIGLFYAFIDNVSVEIYGVEAAGHGLEKGPSAHAA
                     PLCAGNVGVLHGNRTYLMGDENGQIIEGHSIAAGLDYPGVGPEHAYLKDSGRAQYMAI
                     TDKEALEAFHILTKIEGILPALESSHAVAYGIKLAKKLGKNKSIIINLSGRGDKDIHT
                     IAQIEGIEC"
     misc_feature    complement(977064..978218)
                     /gene="trpB"
                     /locus_tag="COSY_0933"
                     /note="tryptophan synthase, beta subunit; Region: trpB;
                     TIGR00263"
                     /db_xref="CDD:232897"
     misc_feature    complement(977070..978158)
                     /gene="trpB"
                     /locus_tag="COSY_0933"
                     /note="Tryptophan synthase-beta:  Trptophan synthase is a
                     bifunctional enzyme that catalyses the last two steps in
                     the biosynthesis of L-tryptophan via its alpha and beta
                     reactions. In the alpha reaction, indole 3-glycerol
                     phosphate is cleaved reversibly to...; Region:
                     Trp-synth_B; cd06446"
                     /db_xref="CDD:107207"
     misc_feature    complement(order(977100..977102,977178..977180,
                     977526..977540,977664..977666,977892..977894,
                     977973..977978))
                     /gene="trpB"
                     /locus_tag="COSY_0933"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:107207"
     misc_feature    complement(977973..977975)
                     /gene="trpB"
                     /locus_tag="COSY_0933"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:107207"
     gene            complement(978245..978853)
                     /gene="trpF"
                     /locus_tag="COSY_0934"
                     /db_xref="GeneID:5172242"
     CDS             complement(978245..978853)
                     /gene="trpF"
                     /locus_tag="COSY_0934"
                     /EC_number="5.3.1.24"
                     /note="catalyzes the formation of
                     1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
                     from N-(5-phospho-beta-D-ribosyl)-anthranilate in
                     tryptophan biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="N-(5'-phosphoribosyl)anthranilate isomerase"
                     /protein_id="YP_001219757.1"
                     /db_xref="GI:148245063"
                     /db_xref="GeneID:5172242"
                     /translation="MRIKICGFTSVDNANQAAMLDIDAIGLVFYDKSPRYVNVGTAID
                     IVNVLPPFVNRVGLFVNSDSNFIDKVLCKVPLDTLQFHGDEPAHECAQYTMPFIKALH
                     MNVQTNIKKMADEYHQASGLLLDVFNKDIYGGTGENFDWRLARVDINLPIILAGGLNS
                     NTVDNAINQVHPYAVDVSSGVESEKGIKDINKIKQFIQKANL"
     misc_feature    complement(978254..978847)
                     /gene="trpF"
                     /locus_tag="COSY_0934"
                     /note="Phosphoribosylanthranilate isomerase (PRAI)
                     catalyzes the fourth step of the tryptophan biosynthesis,
                     the conversion of N-(5&apos;- phosphoribosyl)-anthranilate
                     (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose
                     5-phosphate (CdRP). Most PRAIs are...; Region: PRAI;
                     cd00405"
                     /db_xref="CDD:238237"
     misc_feature    complement(order(978317..978322,978326..978328,
                     978479..978481,978608..978610,978614..978616,
                     978770..978772,978836..978838,978842..978844))
                     /gene="trpF"
                     /locus_tag="COSY_0934"
                     /note="active site"
                     /db_xref="CDD:238237"
     gene            complement(978854..979561)
                     /locus_tag="COSY_0935"
                     /db_xref="GeneID:5172238"
     CDS             complement(978854..979561)
                     /locus_tag="COSY_0935"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219758.1"
                     /db_xref="GI:148245064"
                     /db_xref="GeneID:5172238"
                     /translation="MGKYLNKQQIFDAEDGEDLYVNEEQLKSRLKFFEKKIQVQTDDT
                     PVEEKINNLLEIGRIQVELYKGLDAWEKAFIAFDIARDNELWELAVEACDVMFLSEEP
                     KALKALGHALWLGVTFPINPELSVAMLQHLVDESPKEADICAIAATTAHYITSMRCGL
                     DDDLTFFSSQMMASVADKHSHVTDQSTFDLWCKTLQLDQPEVFLRKLSGAIDQLVVDD
                     WWIDRDKIKTKLDIDGK"
     gene            complement(980324..982657)
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /db_xref="GeneID:5172109"
     CDS             complement(980324..982657)
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /EC_number="5.99.1.2"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="YP_001219759.1"
                     /db_xref="GI:148245065"
                     /db_xref="GeneID:5172109"
                     /translation="MAKNLVIVESPTKAKTIEKFLGKDFSVKSSIGHIRDMPKKNMGI
                     DIDNNFTPTYEITADKKKVVTDLRKAVKVAEKVYLATDEDREGEAIAWHLLEALNLPK
                     DTPRIVFHEITKNAITHAISEPRIVNYRLVDAQQARRIIDRLVGFEISPILWRKISGA
                     RSAGRVQSPVVRLVVEREREISKHIDNSTYKVKAELSSESGEIFKVKLSKEFKSKKQV
                     LAFANILLLANLTITSIEKKPFKRSPKPPFITSTLQQEAFQKLGFSVKQTMILAQNLY
                     RKGFITYMRTDSFILSETAIEAVHKIIVREFGSEYHNTRRYKSKESRAQEAHEAIRPT
                     DLTRSNIFDIEEQAAKLYILIYKRTLSCQMSDAQLQKTKIKINIEGLDEIFIANGEVL
                     VFPGFLRIYDYLLSEDKLLPRLNKGNALNLVNFKARESFSRAKPRYTEASLVKKIEEM
                     GIGRPSTYSTMVSTVQDRNYVTKKNGRGVEREYQLIEIKDNQVIQSQPSEVISGEKNK
                     LFPTNIAYLLTDFLVKYFNNIIDYKFTAKLESDFDTIATQNISWQGVVKNFYIPFHQK
                     IEDAVNISREEIHSMRNLGVDPKSDKPVSVRVGRYGAFVQIGHTDDKDKPTFASFRGL
                     LDIESITLDEALELFNMPRHLGETDNFGTIKANYGRFGPYIQYGKKYVSLKEDIPEEV
                     SLEKALELIKIKEKFDSERIIKIFDGSDIQLLNGRFGPYIWNGKKKGKGQKNITIKKV
                     FGDKPIANLTLEECKKAISGKLKLKKKIVKKEVTKNS"
     misc_feature    complement(980396..982657)
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="DNA topoisomerase I; Provisional; Region: PRK08780"
                     /db_xref="CDD:181555"
     misc_feature    complement(982286..982651)
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="TOPRIM_TopoIA_TopoI: The topoisomerase-primase
                     (TORPIM) domain found in members of the type IA family of
                     DNA topoisomerases (Topo IA) similar to Escherichia coli
                     DNA topoisomerase I.   Type IA DNA topoisomerases remove
                     (relax) negative supercoils in the...; Region:
                     TOPRIM_TopoIA_TopoI; cd03363"
                     /db_xref="CDD:173783"
     misc_feature    complement(order(982400..982402,982406..982408,
                     982412..982414,982619..982621,982628..982633))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="active site"
                     /db_xref="CDD:173783"
     misc_feature    complement(order(982370..982375,982379..982384,
                     982403..982405,982409..982411,982610..982612))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="interdomain interaction site; other site"
                     /db_xref="CDD:173783"
     misc_feature    complement(order(982406..982408,982412..982414))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="putative metal-binding site [ion binding]; other
                     site"
                     /db_xref="CDD:173783"
     misc_feature    complement(982403..982405)
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173783"
     misc_feature    complement(980957..982273)
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="DNA Topoisomerase, subtype IA; DNA-binding,
                     ATP-binding and catalytic domain of bacterial DNA
                     topoisomerases I and III, and eukaryotic DNA topoisomerase
                     III and eubacterial and archael reverse gyrases.
                     Topoisomerases clevage single or double stranded DNA...;
                     Region: TOP1Ac; cd00186"
                     /db_xref="CDD:238110"
     misc_feature    complement(order(982115..982174,982190..982273))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="domain I; other site"
                     /db_xref="CDD:238110"
     misc_feature    complement(order(981254..981259,981269..981271,
                     981275..981280,981287..981292,981803..981805,
                     981827..981829,981839..981841,982208..982210,
                     982220..982222,982232..982234,982241..982246))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="DNA binding groove [nucleotide binding]"
                     /db_xref="CDD:238110"
     misc_feature    complement(order(981089..981091,982130..982132,
                     982142..982144))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="phosphate binding site [ion binding]; other site"
                     /db_xref="CDD:238110"
     misc_feature    complement(order(981359..981391,981455..981511,
                     981521..981565,981929..981967,982073..982102))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="domain II; other site"
                     /db_xref="CDD:238110"
     misc_feature    complement(order(981566..981622,981653..981679,
                     981737..981904,981908..981928))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="domain III; other site"
                     /db_xref="CDD:238110"
     misc_feature    complement(order(981131..981133,981290..981292,
                     981296..981298,981587..981589,981599..981601,
                     981608..981610,981674..981676,981875..981883,
                     981893..981895))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238110"
     misc_feature    complement(order(981674..981676,981803..981805,
                     981809..981811))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="catalytic site [active]"
                     /db_xref="CDD:238110"
     misc_feature    complement(order(980957..981073,981089..981133,
                     981143..981145,981239..981358))
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="domain IV; other site"
                     /db_xref="CDD:238110"
     misc_feature    complement(<980744..980899)
                     /gene="topA"
                     /locus_tag="COSY_0936"
                     /note="Topoisomerase C-terminal repeat; Region:
                     Toprim_C_rpt; pfam13368"
                     /db_xref="CDD:222079"
     gene            complement(982657..983148)
                     /gene="smg"
                     /locus_tag="COSY_0937"
                     /db_xref="GeneID:5172205"
     CDS             complement(982657..983148)
                     /gene="smg"
                     /locus_tag="COSY_0937"
                     /note="nonsense mediated mRNA decay protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Smg protein"
                     /protein_id="YP_001219760.1"
                     /db_xref="GI:148245066"
                     /db_xref="GeneID:5172205"
                     /translation="MTNNILDVLTYMFDYLFEEAEQDATHEIDNTELKAHLSDIGFDT
                     MRIDKALSWLEKIATIQDGKIKPFKTTYQGSIRIYTKTEKIKLNAKSRGFLLFMENIG
                     QLNGNQREMIIDQIMLLGDTSISLEDLKWVVMMVLGNSVDGETSTQWLESIVFLDENR
                     TIQ"
     misc_feature    complement(982660..983136)
                     /gene="smg"
                     /locus_tag="COSY_0937"
                     /note="Protein of unknown function (DUF494); Region:
                     DUF494; pfam04361"
                     /db_xref="CDD:146808"
     gene            984186..984326
                     /gene="rpmH"
                     /locus_tag="COSY_0938"
                     /db_xref="GeneID:5171909"
     CDS             984186..984326
                     /gene="rpmH"
                     /locus_tag="COSY_0938"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="YP_001219761.1"
                     /db_xref="GI:148245067"
                     /db_xref="GeneID:5171909"
                     /translation="MKQKRTFQPSVIKRKRTHGFRLRMRTKSGRAIINARRKKKRKRL
                     AA"
     misc_feature    984195..>984290
                     /gene="rpmH"
                     /locus_tag="COSY_0938"
                     /note="50S ribosomal protein L34; Reviewed; Region: rpmH;
                     PRK00399"
                     /db_xref="CDD:179004"
     gene            984336..984677
                     /gene="rnpA"
                     /locus_tag="COSY_0939"
                     /db_xref="GeneID:5172401"
     CDS             984336..984677
                     /gene="rnpA"
                     /locus_tag="COSY_0939"
                     /EC_number="3.1.26.5"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="YP_001219762.1"
                     /db_xref="GI:148245068"
                     /db_xref="GeneID:5172401"
                     /translation="MSFRLTRNLRVLKPFDYKTIFKHGKIIKGQYWQVLARKIDTPEP
                     RLGLAISKKVHRLAIDRNKTKRIARETFRTHQNDLNHWEFIVMAEHSKPAKNSIMTND
                     LLHLFKKIITY"
     misc_feature    984354..984665
                     /gene="rnpA"
                     /locus_tag="COSY_0939"
                     /note="Ribonuclease P; Region: Ribonuclease_P; pfam00825"
                     /db_xref="CDD:216139"
     gene            984677..984892
                     /locus_tag="COSY_0940"
                     /db_xref="GeneID:5172548"
     CDS             984677..984892
                     /locus_tag="COSY_0940"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219763.1"
                     /db_xref="GI:148245069"
                     /db_xref="GeneID:5172548"
                     /translation="MYYLLLILIKFYQLFISPLLSSNCRFQPTCSQYAYDAIQTHGFF
                     KGLSLSLKRISKCHPWHDSGFDPVPKK"
     misc_feature    984677..984880
                     /locus_tag="COSY_0940"
                     /note="Haemolytic domain; Region: Haemolytic; pfam01809"
                     /db_xref="CDD:201984"
     gene            984912..986537
                     /locus_tag="COSY_0941"
                     /db_xref="GeneID:5172133"
     CDS             984912..986537
                     /locus_tag="COSY_0941"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219764.1"
                     /db_xref="GI:148245070"
                     /db_xref="GeneID:5172133"
                     /translation="MNNQKFFLIIAIFLSIFLLWDKWEITHTIDKNNNLISQTKIKNT
                     STINNSLTNQNLDIPSVTNRNNKLDLPNTDTKNQIPFTTVKTDLLTLEISHKGGTIQN
                     AWLNDYPIEIDSEQKFQLLSDRTGKIFQAQSGLLPQGKMPTHHSIFSSKNIYYQMDGN
                     NLVVPFTWKSENGIIVNKRYHFNKNSYVVGIDYQITNTTNNTLHITSYTQLIRNIPDQ
                     DNMIMPTYTGGARFNDQDVYEKIEFEDFDDQPKTSYKGGWMAMIEHYFFVAVIPNLNQ
                     IHTYSSKIINDKYLLTVVNPELSIAPGATKTIINSNLYIGPKEQSHIDNVAPGLDKTV
                     DYGILFIIAKPLSELLNWIYSIIHSWGYSIIILTLLIKLAFYKLSEKSYRSMAGMRQL
                     APRLKKLKETYGDNKQKLGKKTMELYKKEKINPASGCLPILVQIPVFISLYWVLLEMV
                     ELRQAPFWYLTDLSAPDPYYILPLIMGISMFIQQKLNPPPPDPIQAKIMMALPFVFTI
                     FFLWFPSGLVLYWMINNILSITQQWVINKRINN"
     misc_feature    985137..986534
                     /locus_tag="COSY_0941"
                     /note="membrane protein insertase; Provisional; Region:
                     PRK01318"
                     /db_xref="CDD:234942"
     misc_feature    985986..986522
                     /locus_tag="COSY_0941"
                     /note="membrane protein insertase, YidC/Oxa1 family,
                     C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592"
                     /db_xref="CDD:234272"
     gene            986546..987406
                     /locus_tag="COSY_0942"
                     /db_xref="GeneID:5172137"
     CDS             986546..987406
                     /locus_tag="COSY_0942"
                     /note="taurine catabolism dioxygenase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219765.1"
                     /db_xref="GI:148245071"
                     /db_xref="GeneID:5172137"
                     /translation="MSILNNLDEYKCWRDDKLANSNTNIETCLIEINNPFKIIKSEKD
                     KIKLLCQKNNFALFHIKQQNNYPRAIIAMNKQLGLVDYDSHLYVLNQGLANITKNVKK
                     DQAKFIPYTDKAIGWHTDGYYNKTDQRIRAFSLFCVTPASYGGENKWINQQIVYLQLR
                     ESNPDVAMALTHAQAMSIPEHVINSIVKRRTSIGAIFFIDQPTSQLYMRYTQRKKNII
                     YSNSQEVRQAITVLDKYLRTTTKYHFSHTMDANQGILCNNILHKRSAFTDNPTNPRSL
                     LRGRYFNRLN"
     misc_feature    <986894..987379
                     /locus_tag="COSY_0942"
                     /note="Clavaminic acid synthetase (CAS) -like;  CAS is a
                     trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase
                     carrying out three reactions in the biosynthesis of
                     clavulanic acid, an inhibitor of class A serine
                     beta-lactamases. In general, Fe(II)-2OG oxygenases...;
                     Region: CAS_like; cl00184"
                     /db_xref="CDD:241666"
     misc_feature    order(986897..986899,986903..986905,986984..986986,
                     987326..987328,987365..987367)
                     /locus_tag="COSY_0942"
                     /note="active site"
                     /db_xref="CDD:238154"
     misc_feature    order(986897..986899,986903..986905,987326..987328)
                     /locus_tag="COSY_0942"
                     /note="iron coordination sites [ion binding]; other site"
                     /db_xref="CDD:238154"
     misc_feature    order(986906..986908,986912..986914,986921..986923,
                     987092..987094,987377..987379)
                     /locus_tag="COSY_0942"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238154"
     gene            987820..988353
                     /gene="kdsC"
                     /locus_tag="COSY_0943"
                     /db_xref="GeneID:5172149"
     CDS             987820..988353
                     /gene="kdsC"
                     /locus_tag="COSY_0943"
                     /EC_number="3.1.3.45"
                     /note="KDO 8-P phosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-D-manno-octulosonate 8-phosphate
                     phosphatase"
                     /protein_id="YP_001219766.1"
                     /db_xref="GI:148245072"
                     /db_xref="GeneID:5172149"
                     /translation="MQLSNKFYLKAKNIKLIIFDVDGVLTDGGLYFSDKGIELKRFNS
                     LDGLGIKLLKQNGIESAIISARSSKNVMYRMKNLDIKHFYQGQDNKIVAFNNLIKKLS
                     LKTEQVAYIGDDIIDLPVMRKIGLPIAVSNAHELVKKNAYFITKKIGGHGAVREVCDL
                     LLQSQNTYNKTMDKYLT"
     misc_feature    987862..988200
                     /gene="kdsC"
                     /locus_tag="COSY_0943"
                     /note="HAD-superfamily hydrolase, subfamily IIIA; Region:
                     HAD-SF-IIIA; TIGR01662"
                     /db_xref="CDD:233517"
     misc_feature    987865..988209
                     /gene="kdsC"
                     /locus_tag="COSY_0943"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    order(987877..987885,988009..988014)
                     /gene="kdsC"
                     /locus_tag="COSY_0943"
                     /note="active site"
                     /db_xref="CDD:119389"
     misc_feature    987877..987894
                     /gene="kdsC"
                     /locus_tag="COSY_0943"
                     /note="motif I; other site"
                     /db_xref="CDD:119389"
     misc_feature    988009..988011
                     /gene="kdsC"
                     /locus_tag="COSY_0943"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     gene            complement(988967..989383)
                     /gene="atpC"
                     /locus_tag="COSY_0944"
                     /db_xref="GeneID:5172734"
     CDS             complement(988967..989383)
                     /gene="atpC"
                     /locus_tag="COSY_0944"
                     /EC_number="3.6.3.14"
                     /note="part of catalytic core of ATP synthase;
                     alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in
                     producing ATP from ADP in the presence of the proton
                     motive force across the membrane"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="YP_001219767.1"
                     /db_xref="GI:148245073"
                     /db_xref="GeneID:5172734"
                     /translation="MSTIHVDVVSATESLYSGEVLCVFAPASTGELGIYPKHTALLSI
                     LKPGEVRIETDKGIESIYVSGGIVEVQPDVVTIFSDTAIRANDLDEFKVLEAKQRAQD
                     EMDNSIDTQDISATQAALSESMAQLQMINKMRGKKC"
     misc_feature    complement(988982..989383)
                     /gene="atpC"
                     /locus_tag="COSY_0944"
                     /note="F0F1 ATP synthase subunit epsilon; Validated;
                     Region: atpC; PRK00571"
                     /db_xref="CDD:234796"
     misc_feature    complement(989009..989374)
                     /gene="atpC"
                     /locus_tag="COSY_0944"
                     /note="mitochondrial ATP synthase delta subunit; Region:
                     F1-ATPase_delta; cd12152"
                     /db_xref="CDD:213395"
     misc_feature    complement(order(989144..989152,989156..989158,
                     989174..989191,989255..989269,989333..989335,
                     989342..989344,989348..989356,989363..989365))
                     /gene="atpC"
                     /locus_tag="COSY_0944"
                     /note="gamma subunit interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:213395"
     misc_feature    complement(order(989015..989017,989021..989023,
                     989030..989035,989039..989044,989096..989098,
                     989117..989119,989123..989128,989135..989137,
                     989141..989146,989186..989194,989243..989245,
                     989249..989254,989300..989302,989348..989350))
                     /gene="atpC"
                     /locus_tag="COSY_0944"
                     /note="epsilon subunit interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:213395"
     misc_feature    complement(order(989225..989227,989267..989275,
                     989279..989281,989285..989287,989291..989296,
                     989312..989314,989318..989320))
                     /gene="atpC"
                     /locus_tag="COSY_0944"
                     /note="LBP interface [polypeptide binding]; other site"
                     /db_xref="CDD:213395"
     gene            complement(989384..990763)
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /db_xref="GeneID:5172309"
     CDS             complement(989384..990763)
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /EC_number="3.6.3.14"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. The beta chain is a
                     regulatory subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="YP_001219768.1"
                     /db_xref="GI:148245074"
                     /db_xref="GeneID:5172309"
                     /translation="MSIGKITQIIGAVIDVEFSADNMPKIYDALKVLETGLTLEVQQQ
                     LGDHIVRAIAMGGSEGLKRGLGVTNTGEPIKVPVGVKTLGRIMNVLGEPIDNAGEIGQ
                     EVDWTIHRSAPDYDELAPTTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMME
                     LIRNIAIAHSGYSVFAGVGERTREGNDFYHEMKESNVLNKVSLVYGQMNEPPGNRLRV
                     ALTGLTMAEYFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLASEMGA
                     LQERITSTKKGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRQVAELGIYPAVD
                     PLDSTSRQLDPLIVGEEHYNVARGVQGVLQRYKELKDIIAILGMDELSEEDKRSVSRA
                     RKVQRFLSQPFFVAEVFTGAPGKYVSLKDTIAGFKAILDGEMDDFPEQVFYMTGSIDE
                     VRGRSKEKA"
     misc_feature    complement(989387..990763)
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /note="F0F1 ATP synthase subunit beta; Validated; Region:
                     PRK09280"
                     /db_xref="CDD:236447"
     misc_feature    complement(990551..990748)
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /note="ATP synthase alpha/beta family, beta-barrel domain;
                     Region: ATP-synt_ab_N; pfam02874"
                     /db_xref="CDD:217261"
     misc_feature    complement(989729..990547)
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /note="F1 ATP synthase beta subunit, nucleotide-binding
                     domain. The F-ATPase is found in bacterial plasma
                     membranes, mitochondrial inner membranes and in
                     chloroplast thylakoid membranes. It has also been found in
                     the archaea Methanosarcina barkeri. It uses a...; Region:
                     F1-ATPase_beta; cd01133"
                     /db_xref="CDD:238553"
     misc_feature    complement(order(989741..989743,989747..989749,
                     989753..989758,989783..989788,989819..989827,
                     989831..989833,989852..989854,989864..989869,
                     989876..989878,989927..989929,989948..989950,
                     989960..989962,989975..989980,989984..989992,
                     990008..990010,990020..990022,990029..990031,
                     990119..990121,990134..990142,990206..990208,
                     990215..990223,990404..990406,990410..990412,
                     990416..990421,990425..990427,990476..990478))
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /note="alpha subunit interaction interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:238553"
     misc_feature    complement(990299..990319)
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:238553"
     misc_feature    complement(order(989774..989779,990029..990031,
                     990041..990043,990212..990214,990221..990226,
                     990296..990304,990311..990313))
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238553"
     misc_feature    complement(990041..990055)
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:238553"
     misc_feature    complement(order(989756..989761,989777..989779,
                     989783..989785))
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /note="inhibitor binding site; inhibition site"
                     /db_xref="CDD:238553"
     misc_feature    complement(989387..989707)
                     /gene="atpD"
                     /locus_tag="COSY_0945"
                     /note="ATP synthase alpha/beta chain, C terminal domain;
                     Region: ATP-synt_ab_C; pfam00306"
                     /db_xref="CDD:215848"
     gene            complement(990786..991652)
                     /gene="atpG"
                     /locus_tag="COSY_0946"
                     /db_xref="GeneID:5172319"
     CDS             complement(990786..991652)
                     /gene="atpG"
                     /locus_tag="COSY_0946"
                     /EC_number="3.6.3.14"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. The gamma chain is a
                     regulatory subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="YP_001219769.1"
                     /db_xref="GI:148245075"
                     /db_xref="GeneID:5172319"
                     /translation="MAVGKEIRTQISSIKNTQKITSAMEMVAASKMKKAQDRMLESRP
                     YCEKISNIIGHLAYAHSEFQHPYMNSLKKLQSIGIIIISSDRGLCGGLNTNLFRYILR
                     QVVEYQANGIKVDICTIGKKATLFFKNFGLNVKSVLTDLGDSPHFDDLLGTIKIMLDG
                     FDLGEIQQLSVAYNKFENTMIQIPTIMQLVPIVSIKSDNINHYWDYIYEPNAQEVLSA
                     LLVRYIEALVYQGLVENISCEQSSRMIAMKSATDNAGDMVKELELIYNKARQAAITQE
                     ISEIVSGGATAV"
     misc_feature    complement(990804..991640)
                     /gene="atpG"
                     /locus_tag="COSY_0946"
                     /note="mitochondrial ATP synthase gamma subunit; Region:
                     F1-ATPase_gamma; cd12151"
                     /db_xref="CDD:213394"
     misc_feature    complement(order(990804..990818,990822..990824,
                     990831..990836,990843..990848,990852..990857,
                     990864..990866,990882..990884,990891..990896,
                     990903..990905,991266..991268,991275..991280,
                     991287..991292,991380..991391,991395..991397,
                     991560..991565,991572..991577,991581..991586,
                     991593..991595,991605..991607,991623..991625,
                     991638..991640))
                     /gene="atpG"
                     /locus_tag="COSY_0946"
                     /note="core domain interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:213394"
     misc_feature    complement(order(990987..990989,990996..991001,
                     991008..991010,991497..991502,991509..991511,
                     991518..991523,991527..991532))
                     /gene="atpG"
                     /locus_tag="COSY_0946"
                     /note="delta subunit interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:213394"
     misc_feature    complement(order(990987..990992,990999..991001,
                     991233..991250,991281..991283))
                     /gene="atpG"
                     /locus_tag="COSY_0946"
                     /note="epsilon subunit interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:213394"
     gene            complement(991666..993207)
                     /gene="atpA"
                     /locus_tag="COSY_0947"
                     /db_xref="GeneID:5172340"
     CDS             complement(991666..993207)
                     /gene="atpA"
                     /locus_tag="COSY_0947"
                     /EC_number="3.6.3.14"
                     /note="produces ATP from ADP in the presence of a proton
                     gradient across the membrane; the alpha chain is a
                     catalytic subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="YP_001219770.1"
                     /db_xref="GI:148245076"
                     /db_xref="GeneID:5172340"
                     /translation="MQLNAHEISDLIKKQIEGFDFTAEARTEGSVVSVSDGIVRIHGL
                     GDVQFGEMIEFSNNTFGMALNLEQDSVGAVILGDYLHILEGDIVKCTNRLVEVPVGEA
                     MLGRVVNPLGKAIDGKGDIDAQGVRPLEVMAPGVIDRKSVDQPIQTGIKAIDAMVPVG
                     RGQRELIIGDRQTGKTAVAIDAIINQRDSGIRCVYVAIGQKDSSVATVVRKLEEYGAL
                     ANTIIVVAGAAVSPALQYIAPYAGCAMAEYFRDRGEDVLIVYDDLTKQAWAYREVSLL
                     LKRPPGREAYPGDVFYLHSRLLERASRVNADYVEKMTNGKVKGQTGSLTALPIIETQG
                     GDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINVGLSVSRVGGAAQTNIIKKLGGG
                     IRLDLAQYRELVAFAQFSSDLDVETKAQIDRGQRVTELMKQNQYSPLSIAEMATLLFS
                     ANSGLLDDIEVNKIVDFEVSLIAYMKVNQVSLMNRINEIGNYNDKISNELQVAIDDFK
                     TNYTW"
     misc_feature    complement(991672..993207)
                     /gene="atpA"
                     /locus_tag="COSY_0947"
                     /note="F0F1 ATP synthase subunit alpha; Validated; Region:
                     PRK09281"
                     /db_xref="CDD:236448"
     misc_feature    complement(992932..993123)
                     /gene="atpA"
                     /locus_tag="COSY_0947"
                     /note="ATP synthase alpha/beta family, beta-barrel domain;
                     Region: ATP-synt_ab_N; pfam02874"
                     /db_xref="CDD:217261"
     misc_feature    complement(992074..992928)
                     /gene="atpA"
                     /locus_tag="COSY_0947"
                     /note="F1 ATP synthase alpha, central domain. The F-ATPase
                     is found in bacterial plasma membranes, mitochondrial
                     inner membranes and in chloroplast thylakoid membranes. It
                     has also been found in the archaea Methanosarcina barkeri.
                     It uses a proton gradient to...; Region: F1_ATPase_alpha;
                     cd01132"
                     /db_xref="CDD:238552"
     misc_feature    complement(order(992080..992082,992113..992115,
                     992122..992127,992158..992160,992167..992169,
                     992311..992313,992323..992325,992332..992334,
                     992344..992346,992359..992364,992368..992376,
                     992392..992397,992578..992580,992587..992592,
                     992596..992607,992692..992697,992785..992787,
                     992791..992793,992800..992805,992809..992814,
                     992860..992865))
                     /gene="atpA"
                     /locus_tag="COSY_0947"
                     /note="beta subunit interaction interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:238552"
     misc_feature    complement(992680..992703)
                     /gene="atpA"
                     /locus_tag="COSY_0947"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:238552"
     misc_feature    complement(order(992080..992082,992110..992115,
                     992128..992130,992167..992169,992215..992217,
                     992413..992415,992422..992427,992608..992610,
                     992623..992625,992677..992685,992695..992697))
                     /gene="atpA"
                     /locus_tag="COSY_0947"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238552"
     misc_feature    complement(992425..992439)
                     /gene="atpA"
                     /locus_tag="COSY_0947"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:238552"
     misc_feature    complement(991780..992049)
                     /gene="atpA"
                     /locus_tag="COSY_0947"
                     /note="ATP synthase alpha/beta chain, C terminal domain;
                     Region: ATP-synt_ab_C; pfam00306"
                     /db_xref="CDD:215848"
     gene            complement(993234..993785)
                     /gene="atpH"
                     /locus_tag="COSY_0948"
                     /db_xref="GeneID:5172298"
     CDS             complement(993234..993785)
                     /gene="atpH"
                     /locus_tag="COSY_0948"
                     /EC_number="3.6.3.14"
                     /note="F1 sector"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1-type ATP synthase delta subunit"
                     /protein_id="YP_001219771.1"
                     /db_xref="GI:148245077"
                     /db_xref="GeneID:5172298"
                     /translation="MKLAVIAKPYANAIFELAQQDNSHLQWKMVLDVGAYLLLDKKMR
                     RLIASPNILEQDKLSTIKALLMSILNRELDAHEAMFISVLLDNNRIGILPSIATLFES
                     LINITNNIKIFTIISSYQLSKSEKEQIVSDLMNQYNKTVSIDIVVDKDLVGGVIIKDG
                     DKVIDISIKARVDELGLRLSKTH"
     misc_feature    complement(993243..993785)
                     /gene="atpH"
                     /locus_tag="COSY_0948"
                     /note="F0F1 ATP synthase subunit delta; Provisional;
                     Region: PRK13429"
                     /db_xref="CDD:237386"
     misc_feature    complement(993333..993785)
                     /gene="atpH"
                     /locus_tag="COSY_0948"
                     /note="F0F1-type ATP synthase, delta subunit
                     (mitochondrial oligomycin sensitivity protein) [Energy
                     production and conversion]; Region: AtpH; cl17210"
                     /db_xref="CDD:247764"
     gene            complement(993792..994265)
                     /gene="atpF"
                     /locus_tag="COSY_0949"
                     /db_xref="GeneID:5172377"
     CDS             complement(993792..994265)
                     /gene="atpF"
                     /locus_tag="COSY_0949"
                     /EC_number="3.6.3.14"
                     /note="F0 sector"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1-type ATP synthase B subunit"
                     /protein_id="YP_001219772.1"
                     /db_xref="GI:148245078"
                     /db_xref="GeneID:5172377"
                     /translation="MNINLTMFGQLIMFAMFTWFCMKFIWPPIVMAMEERQKRIEGGL
                     LAAERGRFEKAEAQIKAKEIINQSKSLAAEIIANATRQALNMVEDAKYIALKEAGKVK
                     EQAQAQLEQDTICVRNELKNQVSDLVIQGVNAVLDKEVDVKLHQQMLGKLSESLS"
     misc_feature    complement(993798..994265)
                     /gene="atpF"
                     /locus_tag="COSY_0949"
                     /note="F0F1 ATP synthase subunit B; Validated; Region:
                     PRK05759"
                     /db_xref="CDD:180240"
     misc_feature    complement(993828..994265)
                     /gene="atpF"
                     /locus_tag="COSY_0949"
                     /note="F0F1-type ATP synthase, subunit b [Energy
                     production and conversion]; Region: AtpF; COG0711"
                     /db_xref="CDD:223783"
     gene            complement(994301..994534)
                     /gene="atpE"
                     /locus_tag="COSY_0950"
                     /db_xref="GeneID:5172331"
     CDS             complement(994301..994534)
                     /gene="atpE"
                     /locus_tag="COSY_0950"
                     /EC_number="3.6.3.14"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit C is part of the
                     membrane proton channel F0"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="YP_001219773.1"
                     /db_xref="GI:148245079"
                     /db_xref="GeneID:5172331"
                     /translation="MEQSILFLAGSILMGLGALGAAVGIGILGAKFLEGAARQPELIP
                     MLRTQMFIVMGLVDAVPMIAVGISMYILFAVAG"
     misc_feature    complement(994307..>994444)
                     /gene="atpE"
                     /locus_tag="COSY_0950"
                     /note="F0F1 ATP synthase subunit C; Validated; Region:
                     PRK06876"
                     /db_xref="CDD:180739"
     gene            complement(994562..995416)
                     /gene="atpB"
                     /locus_tag="COSY_0951"
                     /db_xref="GeneID:5172325"
     CDS             complement(994562..995416)
                     /gene="atpB"
                     /locus_tag="COSY_0951"
                     /EC_number="3.6.3.14"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit A is part of the
                     membrane proton channel F0"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="YP_001219774.1"
                     /db_xref="GI:148245080"
                     /db_xref="GeneID:5172325"
                     /translation="MSSTNEVITSGSYIKHHLQNLTYGQFPDGYWGFAHTSEQAKEMG
                     FLAVHLDTLSISFVLGMLFLSFFYRIGKKMTYDTPSGAQNFIESVISYINENVRGSFN
                     GQNPMVAPLALTTFIWIVLMNAMDLVPVDWLPYIAQKIGVWFGADLHHVFFKVVPTTD
                     LNATLGMSIGIFILIIYYSIKEKGMGGFVAELTFHPFGKMMLPFNLFLEGVNLIAKPV
                     SLALRLFGNMYAGEMIFILIALLPFWIQWSLSLPWAIFHILIVLLQAFIFMTLVIVYM
                     DMAHQKEY"
     misc_feature    complement(994568..995401)
                     /gene="atpB"
                     /locus_tag="COSY_0951"
                     /note="F0F1-type ATP synthase, subunit a [Energy
                     production and conversion]; Region: AtpB; COG0356"
                     /db_xref="CDD:223433"
     misc_feature    complement(994568..995293)
                     /gene="atpB"
                     /locus_tag="COSY_0951"
                     /note="F0F1 ATP synthase subunit A; Validated; Region:
                     PRK05815"
                     /db_xref="CDD:235617"
     gene            complement(995416..995763)
                     /locus_tag="COSY_0952"
                     /db_xref="GeneID:5172302"
     CDS             complement(995416..995763)
                     /locus_tag="COSY_0952"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219775.1"
                     /db_xref="GI:148245081"
                     /db_xref="GeneID:5172302"
                     /translation="MATRSEWPKVQLSALLMVSIYFSMNNVAIAAIYGGIIGLLNTSL
                     INRHTNKQKGKLNISPGIDVIMMSVSVIMRMTLLVLLTFFGLLIIGLAPEALIIGLVL
                     GQIGFLIDRVINR"
     gene            995954..997240
                     /gene="sqr"
                     /locus_tag="COSY_0953"
                     /db_xref="GeneID:5172159"
     CDS             995954..997240
                     /gene="sqr"
                     /locus_tag="COSY_0953"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide-quinone reductase"
                     /protein_id="YP_001219776.1"
                     /db_xref="GI:148245082"
                     /db_xref="GeneID:5172159"
                     /translation="MSHVVVIGASTGGLPFAYDIKKTLGKDHQVTVISNNPNFNFIPS
                     NPWLAVGWRSEENISFLLEPHLKRKDIELIIGEASEIKPNDNQVIVGNQVINYDYLVL
                     ATGPKLAFDEIEGLGPEGHSVSICTTAHAESARQEWKKFCTSGGGPIVVGAVQGASCF
                     GPAYEFATIMDTDLKKQGIRDKCPITFITAEPYIGHLGLGGVGDSKGLLESEFRQRHI
                     KWITNAKVTNIATNKVTVDQVNDEGKVVKTIEIATQYTMMLPAFKGVDIVAKLADIDT
                     GFVNPRGFVIVNDYQQSPVKDNIFSIGVNIAIPPVEETPVMCGTPKTGYMIESMVTAV
                     VHNIEEMIANKAPTHIPTWNAVCIADMGDTGVTFVAMPQIPPRNVTWAKKGKMMHLAK
                     IAFEKFFIRNMKTGNSEPAYQKYIFKILGIERLKKK"
     misc_feature    995960..996862
                     /gene="sqr"
                     /locus_tag="COSY_0953"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox_2; pfam07992"
                     /db_xref="CDD:219686"
     gene            complement(997967..998785)
                     /locus_tag="COSY_0954"
                     /db_xref="GeneID:5172024"
     CDS             complement(997967..998785)
                     /locus_tag="COSY_0954"
                     /EC_number="2.7.1.23"
                     /note="bifunctional inorganic polyphosphate / ATP-NAD
                     kinase."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD+ kinase"
                     /protein_id="YP_001219777.1"
                     /db_xref="GI:148245083"
                     /db_xref="GeneID:5172024"
                     /translation="MFKTIGIITKPNDSVSEDTAIKLSEFLLTYHVDVVSGNKSIIQE
                     ADLIIVVGGDGSILSTARSFVDNNIPILGINLGRLGFLADVSLTGMFDIVSEVLDGKY
                     IKEERCLLSCQIKQNNRILDNFLALNDVIIHRKEHLKMVEFDVYIDNKLVNNQRADGL
                     IITTPTGSTAYALSSGGPIMHPGVNAIGLVSICPHTMSHRPLLIPGDSEVMIQVKDSD
                     DGTIVSFDGQTSIVIKVGQDICVRQHSSFINLLHPKDYNYFEIIRSKLHWGHKL"
     misc_feature    complement(997970..998782)
                     /locus_tag="COSY_0954"
                     /note="NAD kinase [Coenzyme metabolism]; Region: nadF;
                     cl01255"
                     /db_xref="CDD:242395"
     misc_feature    complement(998027..998776)
                     /locus_tag="COSY_0954"
                     /note="ATP-NAD kinase; Region: NAD_kinase; pfam01513"
                     /db_xref="CDD:216543"
     gene            998909..999484
                     /gene="grpE"
                     /locus_tag="COSY_0955"
                     /db_xref="GeneID:5172165"
     CDS             998909..999484
                     /gene="grpE"
                     /locus_tag="COSY_0955"
                     /note="heat shock protein"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone GrpE"
                     /protein_id="YP_001219778.1"
                     /db_xref="GI:148245084"
                     /db_xref="GeneID:5172165"
                     /translation="MSNKMTKKKSEKKNQERASVEKKDIETTTKVDLQTPQDEDLQEQ
                     LAQAQQSAKDNWDKLLRSRAEMENLKRRNAKDVENAHKFALDRFVKALLEVKDSLSMG
                     IKTAQEEKATVKHIVEGLEMTDKVFLSTLKKFGVEMINPEGETFNPELHEAVTMVPMT
                     DKDPNSVLEVVQFGFTLNERLVRPAMVVVVQ"
     misc_feature    999062..999481
                     /gene="grpE"
                     /locus_tag="COSY_0955"
                     /note="GrpE; Region: GrpE; pfam01025"
                     /db_xref="CDD:216249"
     misc_feature    999062..999475
                     /gene="grpE"
                     /locus_tag="COSY_0955"
                     /note="GrpE is the adenine nucleotide exchange factor of
                     DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the
                     ATPase domain of Hsp70 catalyzing the dissociation of ADP,
                     which enables rebinding of ATP, one step in the Hsp70
                     reaction cycle in protein folding; Region: GrpE; cd00446"
                     /db_xref="CDD:238252"
     misc_feature    order(999068..999073,999080..999085,999092..999094,
                     999104..999106,999113..999118,999158..999160,
                     999170..999172,999179..999181,999200..999202,
                     999212..999214,999266..999268,999275..999277,
                     999308..999310)
                     /gene="grpE"
                     /locus_tag="COSY_0955"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238252"
     misc_feature    order(999119..999121,999350..999352,999359..999373,
                     999419..999421,999446..999448,999458..999460)
                     /gene="grpE"
                     /locus_tag="COSY_0955"
                     /note="hsp70 (ATPase domain) interactions [polypeptide
                     binding]; other site"
                     /db_xref="CDD:238252"
     gene            1000568..1002799
                     /gene="dsbD"
                     /locus_tag="COSY_0956"
                     /db_xref="GeneID:5171870"
     CDS             1000568..1002799
                     /gene="dsbD"
                     /locus_tag="COSY_0956"
                     /EC_number="1.8.1.8"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbD"
                     /protein_id="YP_001219779.1"
                     /db_xref="GI:148245085"
                     /db_xref="GeneID:5171870"
                     /translation="MKRLLISLILILSTFLLAQVENDLLPVNKAFIFKAEVVNNKILL
                     NWKIKKNYFLYKEKIKIYADFSAQLGNAKFPKTKIRNDEFFGKIGIYRDNTIVVVPIL
                     KGGAKSILLTVNYQGCSDLGVCYPPITKSVVLDISSIHSTSLDNNSFNLLSQATNKVQ
                     SLVKNSIPTSNKPLSVDNAFKFSVVAINNNTLLAKWDIHQEYYLYHNKFLFDIKGATF
                     GNIVISKGKIKDDKFLGKIEVHKDALEVEIPLTDINTKSITLIIKYQGCWEGGVCFSP
                     QEKTINIMLPSQTNNPKINALSKKKSIYTPNIVQIELNETDQITALFQQENILLVLAS
                     FFGFGLLLSLTPCVFPMIPILSGIIVGQKEEVSTKKALIMSIVFVLSMSIAYSIVGVF
                     AGYFGENLQVLFQDPWVLSIFSLIFVTLAFSMFGYYEIQLPTSLQEKITKINNDQKGG
                     HLISVAIMGFLSALIIGPCVTPPLAGALIYIGQTGDALLGGISLFIMSLGMGSLLIIV
                     GAGVSKLPKADGWMESIKYIFGILMLAIAIYLLDRIISPLTSLILWAMLITISPIAMG
                     ALNTQINTSKPWQRIFKALGLIILGYGILLWILVARGGGDMLQPLSSWRSSNIEIESD
                     HLKFKQIKSISDLEQVLIQTKNNNQIVMLDFYANWCTSCKELELFIFSNTHVVNEMSD
                     VIALQADVTENNINDKALMKRFNIVGPPAILFFKNGIENRSQRIIGEINTQNFLSRLN
                     KIK"
     misc_feature    1000628..1000975
                     /gene="dsbD"
                     /locus_tag="COSY_0956"
                     /note="Disulphide bond corrector protein DsbC; Region:
                     DsbC; pfam11412"
                     /db_xref="CDD:221107"
     misc_feature    1001069..1002793
                     /gene="dsbD"
                     /locus_tag="COSY_0956"
                     /note="thiol:disulfide interchange protein precursor;
                     Provisional; Region: dipZ; PRK00293"
                     /db_xref="CDD:234717"
     misc_feature    1001075..1001410
                     /gene="dsbD"
                     /locus_tag="COSY_0956"
                     /note="Disulphide bond corrector protein DsbC; Region:
                     DsbC; pfam11412"
                     /db_xref="CDD:221107"
     misc_feature    <1001606..1002190
                     /gene="dsbD"
                     /locus_tag="COSY_0956"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    1002479..1002787
                     /gene="dsbD"
                     /locus_tag="COSY_0956"
                     /note="DsbD gamma family; DsbD gamma is the C-terminal
                     periplasmic domain of the bacterial protein DsbD. It
                     contains a CXXC motif in a TRX fold and shuttles the
                     reducing potential from the membrane domain (DsbD beta) to
                     the N-terminal periplasmic domain (DsbD...; Region:
                     DsbDgamma; cd02953"
                     /db_xref="CDD:239251"
     misc_feature    order(1002539..1002547,1002551..1002553,1002557..1002559,
                     1002569..1002574,1002689..1002697,1002728..1002730,
                     1002734..1002739,1002746..1002754,1002779..1002781)
                     /gene="dsbD"
                     /locus_tag="COSY_0956"
                     /note="DsbD alpha interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239251"
     misc_feature    order(1002545..1002547,1002554..1002556)
                     /gene="dsbD"
                     /locus_tag="COSY_0956"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239251"
     gene            1002888..1003337
                     /gene="aroQ"
                     /locus_tag="COSY_0957"
                     /db_xref="GeneID:5172301"
     CDS             1002888..1003337
                     /gene="aroQ"
                     /locus_tag="COSY_0957"
                     /EC_number="4.2.1.10"
                     /note="catalyzes the formation of 3-dehydroshikimate from
                     3-dehydroquinate in chorismate biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate dehydratase"
                     /protein_id="YP_001219780.1"
                     /db_xref="GI:148245086"
                     /db_xref="GeneID:5172301"
                     /translation="MDVLLLNGPNLNLLGSREPDYYGTQTLDDITSNLTKIANNVGLT
                     FEHHQDNSEAKLIKYIHNAVDNGVQYIIINPAAFTHTSIALRDAILAVGIEFSEVHLS
                     NIYKRENFRKQSYFSDIAQGIISGFGPQGYEFALQAAIQHIQQLERL"
     misc_feature    1002936..1003289
                     /gene="aroQ"
                     /locus_tag="COSY_0957"
                     /note="Dehydroquinase (DHQase), type II. Dehydroquinase
                     (or 3-dehydroquinate dehydratase) catalyzes the reversible
                     dehydration of 3-dehydroquinate to form
                     3-dehydroshikimate. This reaction is part of two metabolic
                     pathways: the biosynthetic shikimate pathway...; Region:
                     DHQase_II; cd00466"
                     /db_xref="CDD:238262"
     misc_feature    1002936..1003289
                     /gene="aroQ"
                     /locus_tag="COSY_0957"
                     /note="Dehydroquinase class II; Region: DHquinase_II;
                     pfam01220"
                     /db_xref="CDD:189894"
     misc_feature    order(1002936..1002938,1002951..1002953,1003107..1003109,
                     1003113..1003118,1003125..1003127,1003146..1003148,
                     1003185..1003193,1003218..1003220)
                     /gene="aroQ"
                     /locus_tag="COSY_0957"
                     /note="active site"
                     /db_xref="CDD:238262"
     misc_feature    order(1003038..1003052,1003059..1003061,1003068..1003070,
                     1003116..1003118,1003137..1003139,1003146..1003151,
                     1003158..1003160,1003218..1003220)
                     /gene="aroQ"
                     /locus_tag="COSY_0957"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238262"
     misc_feature    order(1003194..1003196,1003200..1003205,1003236..1003241,
                     1003245..1003256,1003260..1003268,1003275..1003277,
                     1003287..1003289)
                     /gene="aroQ"
                     /locus_tag="COSY_0957"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238262"
     gene            1003338..1003784
                     /gene="accB"
                     /locus_tag="COSY_0958"
                     /db_xref="GeneID:5172244"
     CDS             1003338..1003784
                     /gene="accB"
                     /locus_tag="COSY_0958"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="YP_001219781.1"
                     /db_xref="GI:148245087"
                     /db_xref="GeneID:5172244"
                     /translation="MDIRKVKKLMELLEQSSMSEIEIVEGEGSLRISRYRNATMAPPV
                     AITTPVVAPIEVTTGVNPSENNISTVDGHPITSPMVGTFYSAASPNSDAFVKIGQHVN
                     QGDTICIVEAMKIMNQIEADQSGTVTEILCTDGDAVEFSQTLVIIQ"
     misc_feature    1003338..1003778
                     /gene="accB"
                     /locus_tag="COSY_0958"
                     /note="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit; Validated; Region: PRK06302"
                     /db_xref="CDD:235777"
     misc_feature    1003560..1003778
                     /gene="accB"
                     /locus_tag="COSY_0958"
                     /note="The biotinyl-domain or biotin carboxyl carrier
                     protein (BCCP) domain is present in all biotin-dependent
                     enzymes, such as acetyl-CoA carboxylase, pyruvate
                     carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA
                     carboxylase, geranyl-CoA carboxylase; Region:
                     biotinyl_domain; cd06850"
                     /db_xref="CDD:133459"
     misc_feature    order(1003647..1003649,1003674..1003682,1003701..1003703)
                     /gene="accB"
                     /locus_tag="COSY_0958"
                     /note="carboxyltransferase (CT) interaction site; other
                     site"
                     /db_xref="CDD:133459"
     misc_feature    1003677..1003679
                     /gene="accB"
                     /locus_tag="COSY_0958"
                     /note="biotinylation site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133459"
     gene            1003790..1005145
                     /gene="accC"
                     /locus_tag="COSY_0959"
                     /db_xref="GeneID:5172310"
     CDS             1003790..1005145
                     /gene="accC"
                     /locus_tag="COSY_0959"
                     /EC_number="6.3.4.14"
                     /EC_number="6.4.1.2"
                     /note="bifunctional biotin carboxylase / acetyl-CoA
                     carboxylase."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="YP_001219782.1"
                     /db_xref="GI:148245088"
                     /db_xref="GeneID:5172310"
                     /translation="MNKISKVLIANRGEIALRILRTCKELGIKTVAVYSTADKDLKHV
                     RLSDEAVCIGPHPSKDSYLNIPALIAAAEVTHADAIHPGYGFLSENADFAQRVEESGF
                     IFIGPRADNIRTMGDKVAAINTMQKSGVPCIPGSNGSLTEDAAQNTQLARDIGFPIII
                     KASNGGGGRGMRVVEKEADLIDSIEMTKTEALNFFGNCKVYIEKFLTKPRHIEIQILA
                     DEYGNAIHLGERDCSMQRRHQKVVEEAPAPGITPRLRDKISSACTNACKAISYRGAGT
                     FEFLFENNEFYFIEMNTRIQVEHPVTEMITGIDIVREQIRIADGQILSFTQNEVHVKG
                     HAIECRINAEDPNNFMPSPGKITQYHIAGGLGVRVDSHVYNGYVVPPYYDSMIGKLIT
                     FSDTRLGAIIKMQNALDEMVIDGIKTNIALQKRIIDDETFQKGSINIHYLEKMLGNSL
                     I"
     misc_feature    1003799..1005136
                     /gene="accC"
                     /locus_tag="COSY_0959"
                     /note="acetyl-CoA carboxylase biotin carboxylase subunit;
                     Validated; Region: PRK08591"
                     /db_xref="CDD:236307"
     misc_feature    1003799..1004119
                     /gene="accC"
                     /locus_tag="COSY_0959"
                     /note="Carbamoyl-phosphate synthase L chain, N-terminal
                     domain; Region: CPSase_L_chain; pfam00289"
                     /db_xref="CDD:201133"
     misc_feature    1004138..1004767
                     /gene="accC"
                     /locus_tag="COSY_0959"
                     /note="Carbamoyl-phosphate synthase L chain, ATP binding
                     domain; Region: CPSase_L_D2; pfam02786"
                     /db_xref="CDD:190425"
     misc_feature    1004801..1005118
                     /gene="accC"
                     /locus_tag="COSY_0959"
                     /note="Biotin carboxylase C-terminal domain; Region:
                     Biotin_carb_C; smart00878"
                     /db_xref="CDD:214878"
     gene            1005142..1006164
                     /gene="argC"
                     /locus_tag="COSY_0960"
                     /db_xref="GeneID:5172326"
     CDS             1005142..1006164
                     /gene="argC"
                     /locus_tag="COSY_0960"
                     /EC_number="1.2.1.38"
                     /note="catalyzes the reduction of N-acetyl-5-glutamyl
                     phosphate to N-acetyl-L-glutamate 5-semialdehyde in
                     arginine biosynthesis and the reduction of
                     N-acetyl-gamma-aminoadipyl-phosphate to
                     N-acetyl-L-aminoadipate-semialdehyde in lysine
                     biosynthesis; involved in both the arginine and lysine
                     biosynthetic pathways; lysine is produced via the AAA
                     pathway, lysine from alpha-aminoadipate"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="YP_001219783.1"
                     /db_xref="GI:148245089"
                     /db_xref="GeneID:5172326"
                     /translation="MIKVGIIGSTGYTGLELIRLLHNHPNAKIIALCSRINASKSVIK
                     EFPSLISYIDLDFVTPNEKKLFECDIIFFATPHGVAMNSVSKFLNKDIKIIDLGADFR
                     IKDSTEWSKWYGMTHTQGDLLKDAVYGLPEVYNSQIKNATLIANPGCYPTAIILALKP
                     LLETNIIDTKSIIADCKSGVSGAGRSANIATLFCEVNESLKPYNVDQHRHKPETQQVL
                     TDIAGKEVNFFFTPHLVPMTRGMLASIYVDLIKDINVQKLFEKHYQNNKFIHILPTNV
                     YPQTKSVKGTNNCHIGIQKSNNKLIIMSVIDNIIKGASGQAIQNMNLMFGLDEGLGLE
                     QIGLLP"
     misc_feature    1005142..1006161
                     /gene="argC"
                     /locus_tag="COSY_0960"
                     /note="N-acetyl-gamma-glutamyl-phosphate reductase;
                     Validated; Region: argC; PRK00436"
                     /db_xref="CDD:234761"
     misc_feature    1005148..1005564
                     /gene="argC"
                     /locus_tag="COSY_0960"
                     /note="Semialdehyde dehydrogenase, NAD binding domain;
                     Region: Semialdhyde_dh; smart00859"
                     /db_xref="CDD:214863"
     gene            1006174..1006527
                     /locus_tag="COSY_0961"
                     /db_xref="GeneID:5172136"
     CDS             1006174..1006527
                     /locus_tag="COSY_0961"
                     /note="essential respiratory protein A; may be involved in
                     the transfer of iron-sulfur clusters; essential for growth
                     using oxygen or alternate electron acceptors"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="YP_001219784.1"
                     /db_xref="GI:148245090"
                     /db_xref="GeneID:5172136"
                     /translation="MEIKQISEKADIIFSDNAAKKVSTLIEEEQNNNLYLRVYITGGG
                     CSGFSYGFTFDEKRKEGDSSVTNNGVQLVIDPMSYQYLIGATVDYLEDLQGARFIIHN
                     PNAKTTCGCGSSFSV"
     misc_feature    1006198..1006524
                     /locus_tag="COSY_0961"
                     /note="iron-sulfur cluster insertion protein ErpA;
                     Provisional; Region: PRK13623"
                     /db_xref="CDD:184186"
     gene            1006531..1007667
                     /gene="gltA"
                     /locus_tag="COSY_0962"
                     /db_xref="GeneID:5172175"
     CDS             1006531..1007667
                     /gene="gltA"
                     /locus_tag="COSY_0962"
                     /EC_number="2.3.3.5"
                     /note="catalyzes the formation of citrate from acetyl-CoA
                     and oxaloacetate"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="YP_001219785.1"
                     /db_xref="GI:148245091"
                     /db_xref="GeneID:5172175"
                     /translation="MIKYIPGLAGVPATESSISSIDGKNGILTYRGYSIEDLVKYASF
                     EEVSMLLRDGELPDKNRLDNFKDVLHKRYEVKRNIHSMMWSLPATGHPMNVLQTAIAA
                     MATFYPDAGAQNPDSICTQSALTKIISNMSTLVAMWTRISAGYNPIPPSKGMSYAKNF
                     LYMSSGEEPDNNIVKLFDACLILHAEHTINASTFSAMVTASTLANPFASISAAVGTLA
                     GSLHGGANEDVLKMLDEIGNAKNARTYIENRLKNKQIIWGMGHREYSVKDPRANILQN
                     MIESYIKKSNMHFSKRFETALEVERVCEELLSNKGIYPNVDFYSGIVYAEIFKIPQTH
                     FTPIFAMARSSGWTAHWHEQVRHNRIFRPTQIYTGAHFRSYPKK"
     misc_feature    1006531..1007664
                     /gene="gltA"
                     /locus_tag="COSY_0962"
                     /note="citrate synthase; Provisional; Region: PRK14036"
                     /db_xref="CDD:237591"
     misc_feature    1006540..1007655
                     /gene="gltA"
                     /locus_tag="COSY_0962"
                     /note="Citrate synthase (CS) catalyzes the condensation of
                     acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form
                     citrate and coenzyme A (CoA), the first step in the
                     oxidative citric acid cycle (TCA or Krebs cycle).
                     Peroxisomal CS is involved in the glyoxylate...; Region:
                     citrate_synt_like_1_1; cd06112"
                     /db_xref="CDD:99865"
     misc_feature    order(1006546..1006554,1006561..1006581,1006624..1006626,
                     1006666..1006668,1006699..1006701,1006705..1006707,
                     1006762..1006764,1006771..1006776,1006798..1006800,
                     1006810..1006812,1006819..1006824,1006831..1006833,
                     1007089..1007091,1007095..1007097,1007101..1007103,
                     1007110..1007115,1007122..1007127,1007131..1007145,
                     1007152..1007154,1007161..1007163,1007173..1007178,
                     1007182..1007193,1007314..1007319,1007605..1007634)
                     /gene="gltA"
                     /locus_tag="COSY_0962"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:99865"
     misc_feature    order(1006555..1006557,1007089..1007091,1007098..1007100,
                     1007191..1007199,1007203..1007205,1007212..1007214,
                     1007293..1007316,1007323..1007325,1007338..1007340,
                     1007458..1007460,1007464..1007466,1007473..1007475,
                     1007479..1007481,1007545..1007547,1007557..1007559,
                     1007605..1007607,1007614..1007616)
                     /gene="gltA"
                     /locus_tag="COSY_0962"
                     /note="active site"
                     /db_xref="CDD:99865"
     misc_feature    order(1006555..1006557,1007089..1007091,1007098..1007100,
                     1007191..1007196,1007293..1007298,1007302..1007316,
                     1007338..1007340,1007473..1007475,1007557..1007559)
                     /gene="gltA"
                     /locus_tag="COSY_0962"
                     /note="citrylCoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99865"
     misc_feature    order(1007089..1007091,1007098..1007100,1007194..1007199,
                     1007311..1007313,1007338..1007340,1007479..1007481,
                     1007545..1007547,1007557..1007559,1007614..1007616)
                     /gene="gltA"
                     /locus_tag="COSY_0962"
                     /note="oxalacetate/citrate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99865"
     misc_feature    order(1007191..1007196,1007203..1007205,1007212..1007214,
                     1007293..1007310,1007314..1007316,1007323..1007325,
                     1007458..1007460,1007464..1007466,1007473..1007475,
                     1007479..1007481,1007605..1007607)
                     /gene="gltA"
                     /locus_tag="COSY_0962"
                     /note="coenzyme A binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99865"
     misc_feature    order(1007194..1007196,1007311..1007313,1007479..1007481)
                     /gene="gltA"
                     /locus_tag="COSY_0962"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:99865"
     gene            1007670..1008410
                     /gene="ubiE"
                     /locus_tag="COSY_0963"
                     /db_xref="GeneID:5172585"
     CDS             1007670..1008410
                     /gene="ubiE"
                     /locus_tag="COSY_0963"
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone/menaquinone biosynthesis
                     methyltransferase UbiE"
                     /protein_id="YP_001219786.1"
                     /db_xref="GI:148245092"
                     /db_xref="GeneID:5172585"
                     /translation="MENTTHFGFKQVATNDKQSLVRDVFNSVAGKYDLMNDILSFGTH
                     RLWKHYAITSGNIKMGDKVLDIAGGTGDLTMEFTRQVGDNGQVILSDINTTMLHEGRK
                     KLTNKGIFGVEFIQLNAQYLPFKNNTFDCVSIAFGLRNVTNQDQALEEMYRILKPSGC
                     LLILEFSTTNSVLLKKIYDFYSFKIIPKLGDIIANDKTSYQYLAESIRKHPNQKTLKN
                     MVLNAGFDFCEYHNLSSGIVALHKGVKV"
     misc_feature    1007694..1008404
                     /gene="ubiE"
                     /locus_tag="COSY_0963"
                     /note="Methylase involved in ubiquinone/menaquinone
                     biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226"
                     /db_xref="CDD:225136"
     misc_feature    1007853..1008167
                     /gene="ubiE"
                     /locus_tag="COSY_0963"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(1007865..1007885,1007940..1007945,1008018..1008026,
                     1008069..1008071)
                     /gene="ubiE"
                     /locus_tag="COSY_0963"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            1008639..1008968
                     /locus_tag="COSY_0964"
                     /db_xref="GeneID:5172036"
     CDS             1008639..1008968
                     /locus_tag="COSY_0964"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219787.1"
                     /db_xref="GI:148245093"
                     /db_xref="GeneID:5172036"
                     /translation="MFIFLLQCKGLTQLIRQDKINIHSDFKTTQLLINLLKKVDIDFK
                     EIISKYTSDIVPYQLAKLTKKIQKVNIQKINSLEMIKNRLSTLSINKIKTKRHKRKNS
                     WTLCIAF"
     misc_feature    <1008651..>1008821
                     /locus_tag="COSY_0964"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3165"
                     /db_xref="CDD:225706"
     gene            1008944..1010557
                     /gene="ubiB"
                     /locus_tag="COSY_0965"
                     /db_xref="GeneID:5172191"
     CDS             1008944..1010557
                     /gene="ubiB"
                     /locus_tag="COSY_0965"
                     /note="2-octaprenylphenol hydroxylase of ubiquinone
                     biosynthetic pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein"
                     /protein_id="YP_001219788.1"
                     /db_xref="GI:148245094"
                     /db_xref="GeneID:5172191"
                     /translation="MDSMYSFLRFIKISRVLMRYRLDSLVLSTPLLKSFKPLVYLIPW
                     HYFPVKKYTRGQRIRLALEELGPIFIKFGQTLSTRRDLIPKDIGDELAKLQNNCPAFD
                     PIKAKKIIEQSLGESTENLFKRFDIKPLASASIAQIHTALTNDDNEVVIKVVRPDINK
                     VIQHDIKLMYTLAMLFNKHQLSKKLRPIEVVAEFENIILNELDMRIEANNCLKIGKNF
                     KNSSLLYIPKIYPNLCHKNILTIERIHGIPVNDIEQLKANNIDMKQLAEEGVIIFFTQ
                     VFKHNFFHADMHPGNIFVNTNGQYMGVDFGIMGTLTKTDKDFLADIFIAFFNQDYKKV
                     AQIYIDSGWISSTTNIFSFETAVQRICEPMFEKPLGEISFGQVLLELIQEAKNFDITI
                     QPQLLLLDKTLLNIEGLGRQLYPQLNLWTTAKPFLENLVKEKYSIKHTFEKIKDQTPQ
                     LLKDIPELPSMTINAIKQLNQIKDIGHLYIQQTNIIVNQLKNNENKHTSAILAGSMTI
                     LSGILAVNTFWLPSLFSSIIALIFWFQSI"
     misc_feature    1008953..1010545
                     /gene="ubiB"
                     /locus_tag="COSY_0965"
                     /note="ABC1 family; Region: ABC1; cl17513"
                     /db_xref="CDD:248067"
     misc_feature    1008962..1010260
                     /gene="ubiB"
                     /locus_tag="COSY_0965"
                     /note="2-polyprenylphenol 6-hydroxylase; Region: UbiB;
                     TIGR01982"
                     /db_xref="CDD:233667"
     gene            1010714..1011391
                     /gene="rplY"
                     /locus_tag="COSY_0966"
                     /db_xref="GeneID:5171935"
     CDS             1010714..1011391
                     /gene="rplY"
                     /locus_tag="COSY_0966"
                     /note="the Ctc family of proteins consists of two types,
                     one that contains the N-terminal ribosomal protein L25
                     domain only which in Escherichia coli binds the 5S rRNA
                     while a subset of proteins contain a C-terminal extension
                     that is involved in the stress response"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="YP_001219789.1"
                     /db_xref="GI:148245095"
                     /db_xref="GeneID:5171935"
                     /translation="MNLTINALTRNYQGKGANRRLRRNNKIPAIVYGTGKPPSKITLD
                     IFEITHLLKNEETYTSVLNLIVNKNKEAVIIKNLQRHPAKNSITHIDFLRINLNQSII
                     TSIPIQFNGEEDNKAMRLGAVLNQFMTAIEISCLPTNLPHSINVDISHLTIGEHINLT
                     DINIPKGIVITALTHGDIETHNQSIAIIQEPRKMAEIEENILVKAEDSKNKITKDNET
                     NKDKSNL"
     misc_feature    1010714..1011310
                     /gene="rplY"
                     /locus_tag="COSY_0966"
                     /note="50S ribosomal protein L25/general stress protein
                     Ctc; Reviewed; Region: PRK05618"
                     /db_xref="CDD:235534"
     misc_feature    1010723..1010995
                     /gene="rplY"
                     /locus_tag="COSY_0966"
                     /note="Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding
                     domain; Region: Ribosomal_L25_TL5_CTC; cd00495"
                     /db_xref="CDD:198379"
     misc_feature    order(1010741..1010743,1010765..1010773,1010777..1010779,
                     1010807..1010815,1010825..1010827,1010939..1010944,
                     1010948..1010950,1010978..1010980,1010984..1010986,
                     1010990..1010992)
                     /gene="rplY"
                     /locus_tag="COSY_0966"
                     /note="5S rRNA interface [nucleotide binding]; other site"
                     /db_xref="CDD:198379"
     misc_feature    order(1010813..1010815,1010891..1010893,1010927..1010929,
                     1010939..1010941,1010990..1010995)
                     /gene="rplY"
                     /locus_tag="COSY_0966"
                     /note="CTC domain interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:198379"
     misc_feature    order(1010933..1010938,1010945..1010947,1010966..1010968,
                     1010990..1010992)
                     /gene="rplY"
                     /locus_tag="COSY_0966"
                     /note="L16 interface [polypeptide binding]; other site"
                     /db_xref="CDD:198379"
     gene            1011403..1011984
                     /gene="pth"
                     /locus_tag="COSY_0967"
                     /db_xref="GeneID:5172519"
     CDS             1011403..1011984
                     /gene="pth"
                     /locus_tag="COSY_0967"
                     /EC_number="3.1.1.29"
                     /note="Enables the recycling of peptidyl-tRNAs produced at
                     termination of translation"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-tRNA hydrolase"
                     /protein_id="YP_001219790.1"
                     /db_xref="GI:148245096"
                     /db_xref="GeneID:5172519"
                     /translation="MTIKLIVGLGNPGKNYKYHRHNVGFWFCDALAKLYAGNFKKRTK
                     FFGEVTQINIFNHKIQLLKPTTFMNCSGQSIQSIANFYQINADEILIVHDELNINPGI
                     AKIKSGGSHGGHNGLKNTIKILETKAFYRLRIGIGHPGNKLPIVDFVLNTPSKDELDK
                     IQNALNNSLQVIEDVIKNNLDKVIKTLQKKEII"
     misc_feature    1011415..1011930
                     /gene="pth"
                     /locus_tag="COSY_0967"
                     /note="Peptidyl-tRNA hydrolase (PTH) is a monomeric
                     protein that cleaves the ester bond linking the nascent
                     peptide and tRNA when peptidyl-tRNA is released
                     prematurely from the ribosome. This ensures the recycling
                     of peptidyl-tRNAs into tRNAs produced through...; Region:
                     PTH; cd00462"
                     /db_xref="CDD:238259"
     misc_feature    order(1011433..1011435,1011463..1011465,1011601..1011606,
                     1011682..1011684,1011742..1011744)
                     /gene="pth"
                     /locus_tag="COSY_0967"
                     /note="putative active site [active]"
                     /db_xref="CDD:238259"
     misc_feature    1011463..1011465
                     /gene="pth"
                     /locus_tag="COSY_0967"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238259"
     gene            1011997..1013088
                     /locus_tag="COSY_0968"
                     /db_xref="GeneID:5172358"
     CDS             1011997..1013088
                     /locus_tag="COSY_0968"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-dependent nucleic acid-binding protein EngD"
                     /protein_id="YP_001219791.1"
                     /db_xref="GI:148245097"
                     /db_xref="GeneID:5172358"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTQSNIESVNYPFCTIKPNIGIV
                     PINDERLDKLAKIINPKKIIPAIIEFVDIAGLVKGASKGDGLGNQFLTNIRETDAIIH
                     VIRAFDNDNIIHVSGKVSPLDDIEIINTELILADLNVVEKLYKKSLKNTKSGQKDGIP
                     LHNILTKILSVLNNGNSIRTLSFDKEELKLLKGLQLLTIKPILYVANVSEVGFLNNPY
                     LKIIEKLSNKENTQIVTICAKTEDEISELDKNEKQEFLSEMGQSESGLDRLIKAGYKL
                     LGLQTYFTAGAQEVRAWTINIGDKAPQAASKIHSDLKKGFIRAQTIAFSDFIEFKGEK
                     GAKEAGNLRSEGKEYIVQDGDIIHFLYNI"
     misc_feature    1011997..1013085
                     /locus_tag="COSY_0968"
                     /note="GTP-binding protein YchF; Reviewed; Region:
                     PRK09601"
                     /db_xref="CDD:236583"
     misc_feature    1012009..1012827
                     /locus_tag="COSY_0968"
                     /note="YchF GTPase; Region: YchF; cd01900"
                     /db_xref="CDD:206687"
     misc_feature    1012021..1012044
                     /locus_tag="COSY_0968"
                     /note="G1 box; other site"
                     /db_xref="CDD:206687"
     misc_feature    order(1012030..1012032,1012036..1012047,1012615..1012620,
                     1012624..1012626,1012705..1012713)
                     /locus_tag="COSY_0968"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206687"
     misc_feature    1012090..1012113
                     /locus_tag="COSY_0968"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206687"
     misc_feature    1012102..1012104
                     /locus_tag="COSY_0968"
                     /note="G2 box; other site"
                     /db_xref="CDD:206687"
     misc_feature    order(1012207..1012236,1012255..1012284)
                     /locus_tag="COSY_0968"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206687"
     misc_feature    1012210..1012221
                     /locus_tag="COSY_0968"
                     /note="G3 box; other site"
                     /db_xref="CDD:206687"
     misc_feature    1012615..1012626
                     /locus_tag="COSY_0968"
                     /note="G4 box; other site"
                     /db_xref="CDD:206687"
     misc_feature    1012705..1012713
                     /locus_tag="COSY_0968"
                     /note="G5 box; other site"
                     /db_xref="CDD:206687"
     misc_feature    1012831..1013079
                     /locus_tag="COSY_0968"
                     /note="TGS_YchF_C: This subfamily represents TGS
                     domain-containing YchF GTP-binding protein, a universally
                     conserved GTPase whose function is unknown. The N-terminal
                     domain of the YchF protein belongs to the Obg-like family
                     of GTPases, and some members of the...; Region:
                     TGS_YchF_C; cd04867"
                     /db_xref="CDD:133440"
     gene            1013131..1014669
                     /gene="gpm"
                     /locus_tag="COSY_0969"
                     /db_xref="GeneID:5172211"
     CDS             1013131..1014669
                     /gene="gpm"
                     /locus_tag="COSY_0969"
                     /EC_number="5.4.2.1"
                     /note="catalyzes the interconversion of 2-phosphoglycerate
                     and 3-phosphoglycerate"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglyceromutase"
                     /protein_id="YP_001219792.1"
                     /db_xref="GI:148245098"
                     /db_xref="GeneID:5172211"
                     /translation="MKSKKQTKLLLILDGWGYSKTTKNNAIALANTSVWDRLNQTFPH
                     SLIHTSGKDVGLPGKQMGNSEVGHLNLGAGRIVKQDFTRIYNELQNGDFFRNPILRNS
                     LEYANDNNKAIHIMGLLSDGGVHSHEEQIHAMLEMTSRQGCKNVYLHIFTDGRDCAQK
                     SAKKYIKKLESKMKELNTGEIVSLIGRYFSMDRDNRWSRIRYAYELIAKGKAKFLAKS
                     ALNAIELAYARGETDEFIQSTSIKAPTSIKKGDVLILMNYRADRARQITCAFTDEDFQ
                     GFSRGTFVPTQFVCLTEYKKDFNLPVAYPSSKLNNVLGKYLSNLGMTQLRIAETEKYA
                     HVTFFLNGGIEQAFNGEERVLIPSPDVATYDLQPEMSAFELTDALVENIESQKYDLII
                     CNFANTDMVGHSGKLDATIKAVEAVDTCLGIIYKAMFAIGGEMLITADHGNAEQMINP
                     QTNEVHTAHTNNPVPLIFVSNRKADIMKPGKGALSDIAPTLLAMMDIEKPDEMTGNSL
                     LTFK"
     misc_feature    1013131..1014657
                     /gene="gpm"
                     /locus_tag="COSY_0969"
                     /note="phosphoglyceromutase; Provisional; Region:
                     PRK05434"
                     /db_xref="CDD:235463"
     misc_feature    1013134..1014657
                     /gene="gpm"
                     /locus_tag="COSY_0969"
                     /note="Phosphoglyceromutase [Carbohydrate transport and
                     metabolism]; Region: GpmI; COG0696"
                     /db_xref="CDD:223768"
     gene            1014700..1015371
                     /gene="rpe"
                     /locus_tag="COSY_0970"
                     /db_xref="GeneID:5171938"
     CDS             1014700..1015371
                     /gene="rpe"
                     /locus_tag="COSY_0970"
                     /EC_number="5.1.3.1"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="YP_001219793.1"
                     /db_xref="GI:148245099"
                     /db_xref="GeneID:5171938"
                     /translation="MKQANFIAPSILSADFSRLGEEVDNVLKDGADIIHFDVMDNHYV
                     PNLTIGPLVCEALKNHGVSAPIDIHLMVKPVDNIIPNFIKAGASYITFHPEASEHIDR
                     TLGMIQEGGCKAGLVFNPATPIHVLENVMSKLDIILLMSVNPGFGGQSFIPHTLDKCR
                     EVRKLIDASGRNIRLEIDGGIKINNIHEISKAGADTFVAGSAIFKTDNYKTTIDAMRM
                     KLVEV"
     misc_feature    1014718..1015350
                     /gene="rpe"
                     /locus_tag="COSY_0970"
                     /note="Ribulose-5-phosphate 3-epimerase (RPE). This enzyme
                     catalyses the interconversion of D-ribulose 5-phosphate
                     (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin
                     cycle (reductive pentose phosphate pathway) in
                     chloroplasts and in the oxidative pentose...; Region: RPE;
                     cd00429"
                     /db_xref="CDD:238244"
     misc_feature    1014718..1015350
                     /gene="rpe"
                     /locus_tag="COSY_0970"
                     /note="ribulose-phosphate 3-epimerase; Region: rpe;
                     TIGR01163"
                     /db_xref="CDD:130231"
     misc_feature    order(1014727..1014729,1014733..1014735,1014808..1014810,
                     1014910..1014912,1015129..1015134,1015138..1015143,
                     1015231..1015233,1015237..1015239,1015297..1015302)
                     /gene="rpe"
                     /locus_tag="COSY_0970"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238244"
     misc_feature    order(1014748..1014750,1014757..1014759,1014817..1014819,
                     1014823..1014828,1014832..1014834,1014838..1014849,
                     1014919..1014921,1014931..1014933,1014994..1014996,
                     1015000..1015005,1015057..1015059,1015066..1015068,
                     1015072..1015074,1015084..1015086,1015126..1015128,
                     1015153..1015155,1015159..1015161,1015171..1015173)
                     /gene="rpe"
                     /locus_tag="COSY_0970"
                     /note="hexamer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238244"
     misc_feature    order(1014802..1014804,1014808..1014810,1014904..1014906,
                     1015231..1015233)
                     /gene="rpe"
                     /locus_tag="COSY_0970"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:238244"
     gene            1015636..1016421
                     /gene="rpsB"
                     /locus_tag="COSY_0971"
                     /db_xref="GeneID:5172608"
     CDS             1015636..1016421
                     /gene="rpsB"
                     /locus_tag="COSY_0971"
                     /note="one of the last subunits in the assembly of the 30S
                     subunit; absence of S2 does not inhibit assembly but
                     results in an inactive subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="YP_001219794.1"
                     /db_xref="GI:148245100"
                     /db_xref="GeneID:5172608"
                     /translation="MAKTSMKKMLETGVHFGHRARFWHPKMKRFIYGTRNGIHIINLE
                     KTLPMFNDVLNFINKTVKAGRSILFVGTKRAASNIIKQEAIRCGMPYVNHRWLGGMMT
                     NYKTIKASIKRLKDLEFLAEENFNQFGKKEALIMKREMKKLERSLGGIKDLGSIPDVV
                     FVIDTGIEKNAVAEAKKLHLPIIGIVDTNHNPEGIDYVIPGNDDSIRAIGFYAREIAN
                     TILETKATYSSPINKKVSVKKSETQKPKIKKAPVEQILVKKSY"
     misc_feature    1015660..1016301
                     /gene="rpsB"
                     /locus_tag="COSY_0971"
                     /note="Ribosomal protein S2 (RPS2), involved in formation
                     of the translation initiation complex, where it might
                     contact the messenger RNA and several components of the
                     ribosome. It has been shown that in Escherichia coli RPS2
                     is essential for the binding of...; Region: RPS2; cd01425"
                     /db_xref="CDD:100106"
     misc_feature    order(1015708..1015713,1015738..1015746,1015918..1015920,
                     1015924..1015932,1015939..1015944,1016155..1016157,
                     1016164..1016166)
                     /gene="rpsB"
                     /locus_tag="COSY_0971"
                     /note="rRNA interaction site [nucleotide binding]; other
                     site"
                     /db_xref="CDD:100106"
     misc_feature    order(1016161..1016166,1016170..1016172,1016212..1016223)
                     /gene="rpsB"
                     /locus_tag="COSY_0971"
                     /note="S8 interaction site; other site"
                     /db_xref="CDD:100106"
     misc_feature    1016266..1016283
                     /gene="rpsB"
                     /locus_tag="COSY_0971"
                     /note="putative laminin-1 binding site; other site"
                     /db_xref="CDD:100106"
     gene            1016621..1017493
                     /gene="tsf"
                     /locus_tag="COSY_0972"
                     /db_xref="GeneID:5172667"
     CDS             1016621..1017493
                     /gene="tsf"
                     /locus_tag="COSY_0972"
                     /note="EF-Ts; functions during elongation stage of protein
                     translation; forms a dimer; associates with EF-Tu-GDP
                     complex and promotes exchange of GDP to GTP resulting in
                     regeneration of the active form of EF-Tu"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="YP_001219795.1"
                     /db_xref="GI:148245101"
                     /db_xref="GeneID:5172667"
                     /translation="MKITASLVKKLRQRMGAGMMDCKKALNATNGNIEKAIDLMRTLN
                     TTKSAKKLDRITIEGLVKINISANKKTVTILEVNSETDFVTKSDTFISFVNMLGVLAL
                     KTTPTNIEEFLSQPLSNGDSIEKAREEIIAKVGENITIRRVQTIKTNNGIIGTYKHMD
                     RIAVVTILEKGDETLAKDIAMHIAATNPECITEAELSSDLLEREKAIFIEQSKKSGKP
                     NNIIEKMIIGRMKKFVNGVTLYGQPFIKNHDTTIGKLMQLNNTQVKFFVRFEVGEGIE
                     KKEKNFVDEVMAQI"
     misc_feature    1016621..1017490
                     /gene="tsf"
                     /locus_tag="COSY_0972"
                     /note="elongation factor Ts; Provisional; Region: tsf;
                     PRK09377"
                     /db_xref="CDD:236491"
     misc_feature    1016627..1016734
                     /gene="tsf"
                     /locus_tag="COSY_0972"
                     /note="UBA/TS-N domain; Region: UBA; pfam00627"
                     /db_xref="CDD:201355"
     misc_feature    1016786..>1016905
                     /gene="tsf"
                     /locus_tag="COSY_0972"
                     /note="Elongation factor TS; Region: EF_TS; pfam00889"
                     /db_xref="CDD:189759"
     misc_feature    1017062..1017439
                     /gene="tsf"
                     /locus_tag="COSY_0972"
                     /note="Elongation factor TS; Region: EF_TS; pfam00889"
                     /db_xref="CDD:189759"
     gene            complement(1017960..1018544)
                     /locus_tag="COSY_0973"
                     /db_xref="GeneID:5172035"
     CDS             complement(1017960..1018544)
                     /locus_tag="COSY_0973"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219796.1"
                     /db_xref="GI:148245102"
                     /db_xref="GeneID:5172035"
                     /translation="MILKTLLRIRELILLNLEINMKKIIVISTLVAVTSVSAGFFNNS
                     SNNNGYGYGSGSNNWGPLDGGSNWGPMNSGSNIGPFNGANNWGPFDGSSNWGPFNGAN
                     NWGPFSNNNNMNNDSDWGFHYNNKNKTKNVSNASVDGKYEGIADANVKGQADAYAKGQ
                     ADAYAKAQADAYAKGYADAKANATADSRDQVISK"
     gene            complement(1019178..1019588)
                     /locus_tag="COSY_0974"
                     /db_xref="GeneID:5172232"
     CDS             complement(1019178..1019588)
                     /locus_tag="COSY_0974"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219797.1"
                     /db_xref="GI:148245103"
                     /db_xref="GeneID:5172232"
                     /translation="MQKFNWLLFFLLITFNESFAFWSGNYGMSNYNNQANYPYCNSLS
                     FVNYYNIVRNQNIGLNSINFRIKNRVKPSNWLMLTDFSFTFKKNKISQSNFIMNHNIN
                     QYQENFFESMNTTYNDLGYMLFPAAISTLKIEIQ"
     gene            complement(1020279..1020364)
                     /locus_tag="COSY_t35"
                     /db_xref="GeneID:5329748"
     tRNA            complement(1020279..1020364)
                     /locus_tag="COSY_t35"
                     /product="tRNA-Leu"
                     /db_xref="GeneID:5329748"
     gene            complement(1020382..1020753)
                     /gene="secG"
                     /locus_tag="COSY_0976"
                     /db_xref="GeneID:5172253"
     CDS             complement(1020382..1020753)
                     /gene="secG"
                     /locus_tag="COSY_0976"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase SecG subunit"
                     /protein_id="YP_001219798.1"
                     /db_xref="GI:148245104"
                     /db_xref="GeneID:5172253"
                     /translation="MMSFQFILIVHMFLALSLIVLILMQHGKGADAGAAFGAGVSGSV
                     FGVRGANSFLYKLITGLSLGFFLTSLTLAYLATHDGSIGNKPISIMEQVTTGKLVVPD
                     VPIATVTPILNKLDVIDIPDY"
     gene            complement(1020753..1021499)
                     /gene="tpiA"
                     /locus_tag="COSY_0977"
                     /db_xref="GeneID:5171843"
     CDS             complement(1020753..1021499)
                     /gene="tpiA"
                     /locus_tag="COSY_0977"
                     /EC_number="5.3.1.1"
                     /note="Reversibly isomerizes the ketone sugar
                     dihydroxyacetone phosphate to the aldehyde sugar
                     glyceraldehyde-3-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="triosephosphate isomerase"
                     /protein_id="YP_001219799.1"
                     /db_xref="GI:148245105"
                     /db_xref="GeneID:5171843"
                     /translation="MRQVIIAGNWKMNASKEATNILVMDILSGMVDVKSKVIICVPFP
                     YMAQVEALVGCSQLNLGAQDLNINKSGAFTGEVSVDMIKDFGARYVIVGHSERRSLYF
                     ENNEIVAQKVQVALNNNLTPLLCIGELLEDRDSGKTQEVVSEQIQAVIDLVGIDAFKD
                     IIVAYEPVWAIGTGITATPQQAQDTHAFIRSMLAKYDDNVSQITSILYGGSMNPRNAA
                     ELMNCKDIDGGLIGGASLKAQDFLQICKAS"
     misc_feature    complement(1020768..1021493)
                     /gene="tpiA"
                     /locus_tag="COSY_0977"
                     /note="triosephosphate isomerase; Provisional; Region:
                     PRK14567"
                     /db_xref="CDD:173031"
     misc_feature    complement(1020762..1021487)
                     /gene="tpiA"
                     /locus_tag="COSY_0977"
                     /note="Triosephosphate isomerase (TIM) is a glycolytic
                     enzyme that catalyzes the interconversion of
                     dihydroxyacetone phosphate and
                     D-glyceraldehyde-3-phosphate. The reaction is very
                     efficient and requires neither cofactors nor metal ions.
                     TIM, usually...; Region: TIM; cd00311"
                     /db_xref="CDD:238190"
     misc_feature    complement(order(1020801..1020806,1020810..1020812,
                     1020867..1020869,1020984..1020986,1021002..1021004,
                     1021218..1021220,1021467..1021469,1021473..1021475))
                     /gene="tpiA"
                     /locus_tag="COSY_0977"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238190"
     misc_feature    complement(order(1021209..1021214,1021245..1021250,
                     1021257..1021259,1021311..1021313,1021350..1021352,
                     1021359..1021361,1021365..1021373,1021464..1021466,
                     1021473..1021475))
                     /gene="tpiA"
                     /locus_tag="COSY_0977"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238190"
     misc_feature    complement(order(1021002..1021004,1021218..1021220,
                     1021467..1021469))
                     /gene="tpiA"
                     /locus_tag="COSY_0977"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238190"
     gene            complement(1021569..1022087)
                     /locus_tag="COSY_0978"
                     /db_xref="GeneID:5172210"
     CDS             complement(1021569..1022087)
                     /locus_tag="COSY_0978"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001219800.1"
                     /db_xref="GI:148245106"
                     /db_xref="GeneID:5172210"
                     /translation="MNGLEKYFEKLLWGSRYMVLVAVISSLLLSLLLFVITAVDVFAL
                     LVHTFDYIIATSEVRKVLKIELVAHTVGSIDGFLLATILLIFSLGLYELFISDIDEAK
                     ESDQSSKVLVINSLDDLKSKLAKVILMILVVTFFEVSLSMSFNSSLDLIYFSLGILMV
                     SLALYFGSKSSH"
     misc_feature    complement(1021668..1022057)
                     /locus_tag="COSY_0978"
                     /note="Uncharacterized protein family, UPF0114; Region:
                     UPF0114; pfam03350"
                     /db_xref="CDD:217507"
ORIGIN      
        1 atgtctcaaa cttggtcaca atgcctaaac acacttagag atagtatccc actttctcaa
       61 tatagtgtat ggatacaacc cttaaaagca cttgaaaata aaaacacatt atctttatta
      121 gcacctaatt cacaagtact taactacatt aataaaaatc ttaaacccca aataaaaaat
      181 gcagttacac aacataataa aaatttaaaa atttttatcg gtattgcatg caatccaaat
      241 acaaaacaac acaccacacc tttatttgaa gactatacat ttaataattt agtactagga
      301 aatgccaatc aaatggcata tggcgctact aaacaaattg ctgagaatat aaaaacttca
      361 ccatacaatc cttttattat ttatggtaaa tcaggactgg gtaaaaccca cttaatgcaa
      421 gctgctggac acctagcaaa agaaaaaaat ccaaatatta aaataattta tgtaccatta
      481 atggattttg ttagaaacat tacctctagc ttaagacata atactattga aaatattaaa
      541 aatttttacc aatctactga tttattatta gttgatgata tacatttaat tgcaggcaaa
      601 gaaaaatctc aagaagaatt ttttcatatt ttcaattttt tattcagtgg taaaaaacaa
      661 attatattta catgcgacca acccccaaaa aatattaaat cattagaaga tcgtttaaaa
      721 actagatttt cacaaggttt aaatttacat ctaacacccc cagaattaga aatgcgcgct
      781 gctattttac ttaaaaaatc acaaaataaa agaattaaca taaatttaac agaagataca
      841 gcattattta ttgctagcca tattgcgtct aatattagag accttgaggg agcacttctt
      901 aaactcaaag cttttgttga cttttcaaaa atcaatcata gctttatctc taaagaaata
      961 attgaatcag ctttaggaga tctaataaaa ccccaaataa aaaatattga tattaatgat
     1021 atccaaaaag aagtagctaa acattatgcc ttaactattt ccgatttaag ttcaaaatct
     1081 agaaaacaac atacagtact tgctagacaa atggcaatgt ttatttgcta tgaactaagc
     1141 tcactatcac taacaaaaat tggtaaacac ttcggaaata gagatcattc cactgtatta
     1201 cacgctatta aaaaaattaa agaaaaacat atagaaaata ttgaaataaa aaatgattac
     1261 gaattaataa atataaaact agcaaactta taaacatatc caaacaaaat cttatcttaa
     1321 ctgttaataa cattaataac attaacactt taaaaaaatt ataaacatat ccacattttt
     1381 ttacataaaa tacttgatag ttatcaacaa actaaaactc catttttaaa tgaaaaacaa
     1441 ctcttattaa cataaaataa ccatactaat aataataata atatatttaa taaaaggatt
     1501 tttttaatga acatacaact tagagttaaa gaactattag aacctttaca aactgttatt
     1561 agtgtgattg aaaaaaaaca aacattacct atccttgcac atgttcttat tcaacttgaa
     1621 aataatttat taactttaac aacaacagat atggaaattg agataaaaac ttctcaaatt
     1681 atcaaaaaca aagaagaaat ttcttttaca gtatatgcaa aagatctaat taatattatt
     1741 aaaaaattac cagaaaatac aataattaaa tttattatta ataattctaa aatttatatt
     1801 aaagttaata aaaattcatt tgaactcaat acttttagac atcaagattt tccttcatta
     1861 ccaaaaataa aaaataaaaa aaatattaca attaaaagaa aaattttaaa aaatctaatt
     1921 gaaaaaacaa gtttctcaat gggtaatcaa gatattagag catatttaaa tggattatat
     1981 tttgaaatta ataaaaataa tatcgtagtt gttactactg atggtcatcg actttctatt
     2041 ggaaaaataa aacaagctaa taactcctta aacaaaaaaa ctgtaatctt accaagaaaa
     2101 tcaataattg aatttactaa attacttaat aaaaatgaac atgaagaagt taatatttat
     2161 acatcaaata actattttta tcttagtact aataatacaa caataattag taaactaatc
     2221 aatagtaaat tccctaatta tttaccagta attcctacag attttaataa tactattatt
     2281 attaaccgtc tagatttttt aaattcactt cagcaagctt caatttttgt tgaagaacac
     2341 actaaaggtg ttaaattaat attcaaaaat tcacaattat atattttttc aaattcagaa
     2401 agaggacaag ctaaaacaca aattaaaact aaaaatttta ataaaaaaat tgaaattgca
     2461 tttaacatta attatttaat ctcaatttta gaaaaattaa ataccaacga aattaatatg
     2521 ataatcccca atgggaaaaa taaatcatgt ttattgaata gtataaatga tgatatttat
     2581 caatatattg ttatgcctat gagactctaa tatcttataa atttaaaaaa aacttaatct
     2641 tacttcaaaa atataacaaa tacgatttat ttatttgcat ggtataataa tttcattttt
     2701 tacagcatcc atgtctaaaa aacaatcaca aaattcacaa gaatacaaag cttctagtat
     2761 taaagtttta agggggttag atgcagtacg taaacgtcct ggcatgtaca ttggtgatac
     2821 tgatgatggt actggattac accatatggt atttgaagtt gttgataatg caattgatga
     2881 atccttagct ggatattgtt caaaaattaa tattattatt cacgaagata aatcagtttc
     2941 aataaatgat aatggtagag gtattcctat tgatattcat cctgaagaag gcatatctgc
     3001 tgcggaagta attatgacaa tacttcatgc aggaggtaaa tttgataata attcttataa
     3061 agtatcaggg gggctacatg gggtaggtat ttcagttgtc aatgcattaa gtgaatgggt
     3121 taaattaaca gtatatcgta ataataaaat ttactatcaa cactataata aaggtgtacc
     3181 tgaaaaacca atacaagtaa ttggaaaatc aaataaaaca ggaacaatta ttcattttaa
     3241 accaaatatt aatatttttt caaataccga atttaactat gatatattag caaaccgtat
     3301 tcgtgaatta tcatttttaa attcaggagt tcatattgga attgaagaat tttcaacaga
     3361 aaaaaaagat atttttaaat ataaaggggg tattaaatca tttataaaac atcttaataa
     3421 aacaaaaacc ccaattcata atgatattat tgaaattaat actcaacgtg aaaaaattaa
     3481 aattgttgtt gccttacaat ggtctgattc ttatcaacaa agtatttatt gttttactaa
     3541 taatatccct caaagaaatg ggggttccca tttagctgga tttagaggag gcttaactag
     3601 aacagttaat aactatattg ataattctga tatagctaaa aaagaaaaaa attcaataac
     3661 aggcgaagat actcgtgaag gtttaacagc aattattaat ataaaaatac ctgatccaaa
     3721 attttcatca caaactaaag ataaattagt gtctagtgaa gtaagagcac ctattgaatc
     3781 aataataaat gataaactaa atgattattt tttggaaaac ccaaaagaag caaaaattat
     3841 tattaaaaaa attttagatg cttcacgtgc acgtaatgca gctagaaaag caagagaaat
     3901 aactcgtcgt aaaggtttgt ttgacatctc cagcttacca ggtaaattaa gtgattgtca
     3961 aacaaaaaat cctgttgaaa gtgaaatatt tttagttgag ggggattctg cgggaggttc
     4021 tgctaaacaa ggtcgtaatc gacgtacaca agctatttta ccccttaaag gaaaaatatt
     4081 aaatgttgaa aaatcacgtt ttgaaaaaat actatcttca gcagaagttg gtactttaat
     4141 tactgcatta ggatgtggta ttggtaaaga agaatataat cttaataaat tacgttatca
     4201 taaaattgta attatgactg atgcagatgt agatggtgca catattcgta ctttattact
     4261 cacttttttt tatcgttatt taccagaatt aattgaaaat ggatatttat atattgcacg
     4321 gcctccttta tataaaataa aaaaaggaaa acaagaacgt tacttaaaaa acgatcaaga
     4381 attaaacgat tatttattac aagaaggaat taataattca tatttatttg tttcaaaaaa
     4441 aacacctcct atttcaggaa tagaattaga gtttttaata aaagaatatt acaaaattaa
     4501 caaaattttt gataaattat ctaaacatta caatttaaat ttacttaaag caatttccaa
     4561 ttcaaaacct attgatgatt taactaatca taaaaatatg aatacttggt gtacaaattt
     4621 aacaaaaaat ttaaataaaa atttaacact agaaaaaaca cataaagtta tttttaataa
     4681 aaatactaat gaagttgaat atacactata tgtatacgga gttaatattg accatacaat
     4741 attaaattca gtttttttta attcttttga ttatcaatct attaaagaat tttctaaaaa
     4801 aattgaaaat gttattactc aagaatctta tgtaaaaaat ataaataaaa aaattagagt
     4861 tcaatatttt agtcatgtag ttgaattttt gatgaataat gctagaaaag gacaaagttt
     4921 tcaaagatat aaaggtttag gtgaaatgaa ccctaaacaa ctttgggaaa caactatgga
     4981 tcctgaacaa agaactttat ttaaagttaa aattgaagat agtattattt ctgacgaagt
     5041 tttttccacc ttaatgggag atgctgttga accaagaaga aattttattg aagataatgc
     5101 tttgtcagtt aataacttag atttttaata aaaaataagg agataactat gtcaaataaa
     5161 catccagtta ttatagtaac aggatcatct ggcgctggaa caacttttgt aaagcgtgct
     5221 tttgaacata tttttagaaa ggaaagtatt aatcctttga ttattgaagg agatagtttt
     5281 cataaatatg atcgtaattc aatgaaaaag aatgttaaaa aacaagaaga tttaggaaat
     5341 aatttttttt ctcattttgg tcctgatgct aatttattcg aaaaaataga acaaactttt
     5401 aaagattata gtgaaacagg aaaatgtgat cgtcgttatt atttacattc tataaaagag
     5461 gctaataaac ataatcaacg tctaaacact aatctaaatc caggtgaatt tagtccttgg
     5521 gaaaaagtag gtgatggtac agatttgtta ttttatgaag gtttacatgg tgttgttgtt
     5581 acagatgggg tagatatggc tcaatatggt gatttaaaaa ttggggttgt acctagtgtt
     5641 aatcttgaat ggattcaaaa aattcatcgt gacaatacgg aaagaggtta ttcagcagaa
     5701 gaaacagtta gtacaatttt acgtagaatg cctgattata ttaactatat aacaccccag
     5761 ttttcacaaa cagatattaa ttttcaacgg gtggcaacag tagatacttc taatcctttt
     5821 attgccagag atattccaac cccagatgaa agttttatag taattcgttt taatgattta
     5881 gataaaactt ctgttgattt ttcatactta tgtagtatga ttaatggttc ttttatgtct
     5941 agacgtaata ctattgtaat tccaggtgga aaaatgagtt tagcaatgga aattattcta
     6001 tatcctatta ttaaaaaaat gatttaaata ataggatata ttatactatt aactaataaa
     6061 tatataatta catatttata ttattattta gttacaatat ttattaattt attatgaata
     6121 ataattattt taataatatt tttatttttg gtaaacttaa taatattttt attagaaagt
     6181 acttcacttt caagtatttc tttatcagta ttaatcatca tcatcatctt atcacgtaat
     6241 ttaccatcaa cttgtattat gatttgcact tcactttcta tcaatgcttt tagatcaacc
     6301 ttaggccatg gttcattaat aattgctttt ttattaccta atttaagcca taaataatga
     6361 caaatatgag gagttatggg acttaaagta agtaagataa tattgattga ttcagatctt
     6421 aatgctattg attgtgtatc tgttttagta aacttattta ttatatctac tgattccatc
     6481 aatgtagaaa tagctgtatt aaaggtgtat ctacgattaa tatcatcagt aattttcact
     6541 aaattttgat gtatttttct tcggatatgt ttttgtgttt tattgagaaa attaatattt
     6601 aaatgattaa caatatagtc tttagaatca ttaatataaa tactcactaa acgataaact
     6661 ttttttataa atcgatgtgc accttcaaga cctgaattat tccattctaa atcttgcatg
     6721 ggaggggctg caaataaaat aaataaacgt actgtgtcag caccatattt tttaatcatt
     6781 tttgtaggat ccactgtatt tcctttagat ttactcattt taacgccatt ttttaaaacc
     6841 ataccttgag taagtaaatt tttaaatggt tcatcatatt ttattaaacc ctcatctcgt
     6901 aatagtttat tgaaaaatct tgcatataaa agatgtaaga tagaatgttc aaccccccca
     6961 atatattgat caacttctaa ccaataattt acacgtttat caagcatagc attattatta
     7021 ttattacaag tatgacgtgc aaagtaccaa gaagattcaa agaaagtatc aaatgtatcg
     7081 gtttctcgat gcgctttaga accacatttt ggacaaatgg tttgataaaa atttggcatt
     7141 ttttttattg gtgaactaac atcataaaat ttaacttttt caggaagaat aacgggtaaa
     7201 tctttaactt taacagtaac tgaaccacaa tacttgcagt taacaattgg gataggacaa
     7261 ccccaatacc gttgtcttga tataccccaa tcacgtaaac gataattaat ttttttatta
     7321 cccaaatttt tttctatcaa agttttagca atgctttcat atgcttggtt aaaatccata
     7381 ccactaaatt cttctgaatt aaataatttt cctttattaa taataggacc tttatcaata
     7441 ctttcatttt tattaataac ttgcttgata aaaataccgt attttttagc aaatttaaaa
     7501 tctcgtttat catgtgcggg tacactcata attgcacctg taccgtaact cattaataca
     7561 aaattagtaa tccaaatagg aacttcatta tttgttattg ggtgtataca tttaaatcct
     7621 gaatcaatac cttttttatc cattatttca tttaaaatct cagaagtttg tatagtttta
     7681 catttttcaa taaaagattg cacttgataa ttattctttc ctgattctaa tgctaacgga
     7741 tgttcaaatg aaatagctaa ataagtaacc cccattagtg tatctggccg agtagtgtaa
     7801 attataagag gatcagaatt tcttctagaa aaagtaattt ctagcccaat agatttacca
     7861 atccaatttt tttgcataat cttgacggga tctggccaac cataaagttt gtctaaatca
     7921 ttaagtaatt cttctgcata gttagtgata cgtataaacc attgtgagat ttcttttttc
     7981 tcaatcaagg cattagaacg ccacccacgt ccattaatca cttgttcatt tgctaacact
     8041 gtttgatcaa caggatccca attaacaata gcttttttct tatatattaa atttttttta
     8101 aataatttaa taaacagcca ttgttcccaa cgataatact ttggatgaca agttgtaatt
     8161 tcacgagccc aatcataacc aaaacctaat tggtttaatt gagttttcat ataattaata
     8221 tttttatacg tccacttagc tggggattct ttatttttta atgctgcatt ttcagctggt
     8281 aatccaaaac catcccaacc aataggctgc ataacatttt taccttgcat tctttgaaaa
     8341 cgagaaataa catcaccaat actataatta cgtacatgcc ccatatgtaa tcgtccagat
     8401 ggataaggga acatgctaag gcaataatat ttttcttttg aataatcctc tattacttca
     8461 aaagattttt tttctttcca atatttttga gcttgttttt caattttttg cacatcatat
     8521 tttatgttca tagaattctt gatttatcta aataagtatc acattgagat gtagtagaat
     8581 taagttctag tgtacctatt aaatcatcaa tactgtttaa attattatta tttaaatatt
     8641 cactaatacc atgattaatt ttatgacaaa ctaatggatc ataaaaaaga gcagtaccta
     8701 taccaatagc agaagctcct gcaattatga attctattgc atcattagca gttgtaatgc
     8761 cgccttgacc aataatagga atattataat gtttactaac ttgataaact tgataaactt
     8821 ttaatagagc gatgggttta atagccgggc cagatactcc accttgattg ttaccaatga
     8881 ttggtttttt agttgtaata ttaatagcca tacccataag cgtgttgata actgctaaac
     8941 catcagtacc tgcatcaata caacgttggg cactaaaagc aatatcagtt tgattagggg
     9001 atagtttagt aataataggt ttagtagtat ttcttcggca aatttctaca actctataag
     9061 acatatttgg gtcattacca aaagtaactc ctcctttttt aatattagga caagaaatat
     9121 taatttcaat tgcgtgaata tctgtattat caaaacgttt agtaatttct ccatactctt
     9181 caaaggatga accagaaata ttaataataa aattagtttc agttttatct agttttggga
     9241 ggattttatt aattaccaca tcagaaccag gattttgtag tccaatggca ttaatcatcc
     9301 cgctaggtgt ttcagttact cgatggggga tatttcctaa acatcgtttt aaggttgtac
     9361 ccttaagaca aatagcacct acatcagaat tagtaaatcc atcaatattt gtatattctt
     9421 taccaaagcc aacacaacct gataaaagaa caataggtga attaaagaaa agtccacaga
     9481 attggttttt taaattatta ttcatgaata atattataca tttttactgt taaaattatt
     9541 atttatgaaa ggactattca ttagcggtag tgggactaat gttggtaaaa catttattgc
     9601 tcaatattta attaaatttt taacaaatat tctaaaagta cgtgttagaa aaccagttga
     9661 aagtgattgt aaaaataaaa atgggaaatt gataccaaaa gatgctttat tattatctaa
     9721 agcatgtaat attattgagt caattgataa aatatgtcga tataaatttc aggcatgtag
     9781 tagcgcacaa atagcaagtc aagctttagg attaaaactt actttagatg atttggttga
     9841 tgcttgtata gcagatgaat ttgttgttgt tgaaggagct ggtggattgt tatctccaat
     9901 agcaactaaa acattaaata gtgatttagt tcaagcaatt aatgtaccag tagtgctggt
     9961 gattaaagat gagttaggtg cagttaatca ggcgttactt agtattaatg cagctcagca
    10021 ttataagctt aatataagta tggtggtgtt aaatcagata taccctaatt tgttaggtaa
    10081 tgaaaaagaa attactcagt atacaaatgc taatattgtg gtatttaatc aaaatgattt
    10141 aaaatcattt gaaagacaaa ttgaaaaaat tctattagcg gatttaatca agtaatttta
    10201 agtttggttt ttcttcagtt ttaaagaaca tacctttgcc attttcactt gcataaatac
    10261 tattaattgc attaataggc acaaagatat taattaattt tttagaaaat cttgctttaa
    10321 aactaagatt atcattactt ataattaagt tataagtcgc gttactagca atattaagaa
    10381 caattttatt ttgttgaatg aattgctttg gtacaataac acttgaatag gtacaatcga
    10441 ctaatatgtg aggggttagc ttagcatcct ccgtccatgc gtgataagcc ctgattaaat
    10501 atggtgctat agaaagcatc atatttcatt gtattctttt tcgcaatcgg ttaagcttgc
    10561 tttaaaacta tctcgagtaa aaagtctatt tgcataatct ataacagatt ttcctggttt
    10621 tcctagttca atttctagtt tttttaaacg ccataataaa gcacctaagc aagcatccac
    10681 aatagtcatg tcatcacttt taaaaaaagg tttataggca aataaaggca ctaattcaat
    10741 taagttactt tttaaaacct tacgtgcttt atcagcgttt tttttactac ctgattcaat
    10801 aatatctgct agttcaaacc aacaattagg tgctctagta aatctgaaaa taagtaatct
    10861 tttttcagat ttttcaatag ggtctacaga taataacggg ggaaatggga atcgttcatc
    10921 aaggtattcc atcactactg aaagatcgta taaaacaatt cctctgtcaa ataaagtagg
    10981 taatgattga caagggttaa gttctagaat ttcttcagga atttcttcaa tttttaaatt
    11041 tagcacttct ctttcaatat ttttttcagc cattataaaa cgtactacat gagaacgtat
    11101 atctttgggt gatgaataaa gtgttgtcga agcaggatta ggttttgtta acatagtatt
    11161 tacctttaga ataaaaaatt ttaattgaaa aattaatgtt tagtacgcca ttttccatat
    11221 ttgatatctt tccagtattc tatttttaat aaataagaaa aaatgaataa aatcaacaaa
    11281 aaacctaata ctttaatacc aagattaaat cgtactaatt tagctggttc accaacataa
    11341 tctaagaagt tagtaatatc tctaatatct tgatcaaatt ttttactaga tttatcttgt
    11401 tttaatttcc ataaaacatc tggcatagag acgtttttta gtatatggtt atttacacca
    11461 aatatacgtg aattatcttt ataaaaacca tgtaagtaag agtatatcca gtctactcct
    11521 tttgaacgtg atactaaaga taggtctggg ctttgtccaa accattggtt agcatcagta
    11581 actgacatag cagatgtaat tgtttcacca attttttcat tgcctaaaat aaaatgtttt
    11641 tcaatctctg catcagcaat atttaagtct ttaccaatac gattataacg catgaattgg
    11701 attgagtgac agccagaaca gtaattcatg aataatttag cacctcttcg taatgatttt
    11761 ttatcattaa tattagtatt agcctgatct agatgaattt cattgcctga tgcaaaagta
    11821 ttaaaagaga atatcaaaat tgtaactgct attaacaatg tgtgtactat atttttcata
    11881 tatttactcc gttactcgta ttggtaacga cttggttttt ccaatggagg taaaccaagg
    11941 catcaagata aaaaacccaa aataagtaag tgtaaacact cttgctagta atgcattaat
    12001 tggcgttacc ggctgcatac ctaaataacc aagtatgata aaactaataa caaaaattcc
    12061 taaagcaatt ttataaggcc atgaacgata tcgaattgat tttaccttag atctgtctaa
    12121 ccagggcaat gcaattagaa ttaatagtga agcaaacata ccaacaacac ctggaaattg
    12181 tgaaccaaac atagggggta tagctcttaa cactgaatag aaaggtgtta aataccaaag
    12241 tggcgcaatg tgattaggtg tttgaagtgg atttgcttca ataaagttag aactctctaa
    12301 aaaatatcca ttcattgctg gagcaaagaa tacaatagat gaaaaaatca ttaaaaatac
    12361 tactacaccc acaatatcct taacactata gtacggatga aatggaactc cgtctttagg
    12421 aattccatct ttgtttttat tttttttgat ttctataccg tctggattat ttgaacctac
    12481 tgtgtgtaat gccacaatat gtaaaaatac caaaatagct aaaatcaatg gtaaagcaat
    12541 tacatgcaat gaaaagaaac ggtttaaaac aggatcccca acagcgtagt cacccaaaat
    12601 gaaagttaag atttcaggac caaatatggg tactgaacca aatagagaaa taataacttg
    12661 tgctccccag tatgacattt gcccccatgg taatacataa cccataaagg cttctgccat
    12721 caatgcaata tatagcacca ttcctaaaat ccaaattaat tcacggggtg tcttgtacga
    12781 tccataaagt agactacgat gtatatgtaa atatataaca acaaaaaaag cagaggcgcc
    12841 tgttgagtgt aaataacgaa taagccaccc ccagttaaca tcacgcatga tatattctac
    12901 tgatgcaaat gcatggatag catctggttt aaagtgcata gttaaaaaaa ttcctgttac
    12961 aatttgtatt actaatacca acatggctaa tgagccaaaa aaataccaaa aattaaaatt
    13021 tctaggtgtg taatactccg ctaagtgttc attccaaact ttagttaatg gaaatctttg
    13081 atcaatccaa tttttgttat tattcatgta attctcctga ttatgctttt gggtcaatgc
    13141 caattcgaat taaagaatcg gcaacaaaat gataaggcgg aataactaaa tttgttggtg
    13201 ctggaacgcc tgtataaacc cttcctgcta aatcaaattt agagccatgg caaggacaat
    13261 aaaacccccc cttccatgaa tctccaccaa gatcagaagc gcctaattca ggtctatagg
    13321 tgggcgagca acctagatga gtacaaacgc caataataac agcaacatca ggatttattg
    13381 aacgataaag gttttgagca tactttggtt gttgagaaat ttcattacta ttaggatcag
    13441 tcaagatgct atttaacgtc atcaaattct taatagtttt tttatcacgc ttaaaaatcc
    13501 aaacaggttt tttccgccat aaaactctaa ctaattgtcc gttatctaat ttacttatat
    13561 caacatcaat aggtgcacca gcagcttttg ctcttgctga aggcatccat gatgataaaa
    13621 atggtactaa aacaaaacca acgcctatcg caccaacaac gcttgtggca ctagttaaaa
    13681 atcgcctttt ctttaagtct atctcttgtt ctgacatagg ggttaaaatc ctttattaaa
    13741 gtttataaat aaaatctaat tttaaacccg gattattata atatatatta gctttatttg
    13801 atagataatt aatgttagag tgttattaat tgacattaat tttaatttct atatgtgtta
    13861 tagattcaag tgctggtatt tgtatcaaaa tttctagtaa ttttactatt tgtttttgag
    13921 ctctaaaata aatagcatga ttattagtta tcagagttgc tgtgttatct ttaattaagc
    13981 ataatttaat aaatggtttt agtgtgtttg gtagaatctt attaagctca atattgattc
    14041 gattatagga ttttgcttta gtaaacagtt gtccaagcct accattaggt ataaaatttg
    14101 cgagatttgt tagggtttta tactgacaca ttcatctatc tatgagaaaa taagttttta
    14161 aagattaatt taaacatatt ttaatgagta ttataaataa cattctatca aagattgttg
    14221 gttctagaaa tgatcgactt atcaaagttt tatacaaaac tgttaatcaa attactgaat
    14281 tagagtcgaa catgcaagca cttagtgacg agcagcttaa atctaaaact caagaattca
    14341 aagatagatt gaataaaaag gaaactttaa actcaattct tattgaggcg tttgccgtga
    14401 tacgggaggc atcaatcagg gtattagatc ttagacatca tgatgtacaa ctaattggtg
    14461 gtatagttct taataatggt aatattgcag agatggggac aggtgaaggt aaaactttag
    14521 tggcaacctt gcccgcctat cttaatgcac ttaatggtaa gggtgtacat atagttactg
    14581 tgaatgatta cttagcattt cgtgatgcgc agtggatggg aaaagtattt aattttttaa
    14641 gcatgagtgt gggtattatt acctcaaata tgtcgtatga aaataaacaa gttgcttatt
    14701 tatgtgatat tgtttatgca actaataatg agttaggttt tgattatctt cgtgataata
    14761 tggcatttac ttctgaacaa aaagtacaac gaatgcttaa ttttgccatt gtagatgagg
    14821 ttgattcaat tttaattgat gaggctagaa cgcctttgat tatttctggt ccaacggatg
    14881 attatgctca aatttatcaa gctattaatc atatgattcc tcattttact aagcaaatag
    14941 aaagcggggc gggcaaagaa atagttattg aggtggcagg tgattatact gttgacgaaa
    15001 aacataaaca agtattttta actgataatg gacatggtaa agctgaacgt ttattaattg
    15061 atgctggtgc cttgttagag ggcgttagtc tttatgatgc aagtaatatt ttgttaatgc
    15121 agcatattaa ctcagcattg cgtgcacata ttttattcca aaaaaatgtg gactatatta
    15181 tccagaatga tgaagttgta attgttgatg aatttaccgg tagaactatg ttgggtcgtc
    15241 gttggtcaga aggtttacat caagctattg aagctaaaga aagagtaagt attaaaaagg
    15301 aaaaccaaac gcttgcttca attacttttc aaaattattt taggctttat agaacactct
    15361 caggtatgac aggtactgct gatactgaag ctgtagaatt tcaagatatt tacggattag
    15421 aaacagtggt tgttcctcct aataagccat ctacacgtgt agacaaatca gatctaattt
    15481 atttaacaac acaagaaaaa tttaaggcta ttgctcttga agttgctaat tgtcagaaaa
    15541 ctggacagcc agttttggta ggaacgagta gtattgaaaa ttcagaatta atttccactc
    15601 tattagaaaa aaataatatc aaacacgaag ttttaaatgc taagcagcat gagcgagaag
    15661 ctattattat tgctaatgct ggtagtattg gtgcagttac tattgcaact aatatggcag
    15721 gtaggggtac ggatattgtg ttaggcggta aattgcttga acaagcaaca aataagcaaa
    15781 aaattgattg gcagaatcga catgatgatg ttattaaagc aggtggtttg catattgttg
    15841 gtacggagcg taatgaatca cgtcgagtgg ataatcaatt acggggtcgt tctgcgcgtc
    15901 aaggagatgt aggttcaact cgtttttact tatcattaga agataattta atgcgtattt
    15961 ttgctagtga gaaaatgtca tcaacgatgc aaaagttggg tatgaaaaaa ggagagtcaa
    16021 ttgaacataa aatggttaat cgtgctattg aaaatgccca aagaaaagta gaaggtatga
    16081 attatgatgc acgtaaacat cttttagaat atgatgatgt cgctaacgat caaagaaaag
    16141 tcatctatca attacgtgat gatttaatga gtgttaatga tgttcaagac cgatttatta
    16201 gtattaggga aaaagttatt aaacagcttt tttcggatta tatttcagct gaattaatgg
    16261 aagaggattg gaatgttgaa ggattttata atgctctaaa atcagattat tcagtcgatt
    16321 taccattaca acaatggctt aataaaggtg ttgatatcga tgaattacaa tcaagaatta
    16381 ttcaaggaat gagtacaatt tgtgattata aagaagaaac ggttggtact aagcctatgc
    16441 gtgaatttga aaaagcagtt atgctaaaaa ctattgacca ttattggaaa gaacacttag
    16501 caaccatgga ttatttacgt caaagtgtta atttacgggg ttatgcgcaa aagaacccga
    16561 tgcaagagta taaacgtgaa tcgtttgcta tgtttacctc gttgttagat actattaata
    16621 ttgaaattgt taaatcttta tcaaatgtta ctattaatga aaatactgat attttagatg
    16681 tggaacagca aaataatgat gatgcgcaag caacacatag taatccaaat gaacaaacca
    16741 aacaagctag tattactaat aacatacaaa cacaaactga ccaacaaaac acctatcaaa
    16801 gaaaagagaa aaaggtagga agaaatgagc cttgtccttg tggatcaggg aaaaaatata
    16861 aaaaatgtca tggataacta tattgattta atatcaggta ttagttttaa tggtgttgtt
    16921 attaatgaga gaggtataca aaatactaat ccaagcttac ctttattatt cttataagct
    16981 agagcaaatt ttgttaaagc ttactcaaaa ttcaaagatc ttattagagg gtctggctaa
    17041 tattgagatt caaatggcga attatttttc tgatacagta aatttattat tataacagat
    17101 agatattaaa gcaaagaata ttaaaataaa tagcaaatag gagtagatgt ttatttgtgg
    17161 ggtagtgtat tttatttaag catttggttt attaaaatat taatagtaaa gttatactaa
    17221 ccaatgattt gagcgtattt atagattatt tagaagctct tacattttat tttttgatga
    17281 aaaaacttag caaatttgtc atcaaatttt caatcagtaa aagggttatg gatgaaagga
    17341 gtgcttggag taatttatgc aatttaaaat gattcagcca gatgactgtc atttacatat
    17401 tcgttcagga atggcattaa aatcaattat cggtatgacg gttaagcaaa tgggtagagc
    17461 aattattatg cctaatttaa atcctcctat tactaatgtt actcaagcgt gcgcttataa
    17521 agcagaaatt ttatctgcac taccaaaagg aaacagattt aatccattaa tgaccttata
    17581 tttaacagat aatactactt ctaaagatat tcaagaagct attgatcatg atgttatagc
    17641 ggttaagctt taccctgcgg gggcaacgac taattccgat agtggtgtaa ctaatattgc
    17701 taaactttat ccaacactag aaagtatgca aaaactgggt atgccgcttt tagtgcatgg
    17761 agaagtaaca cgtagtgagg tagatatttt tgatcgagag gccgtattta ttgatgaggt
    17821 gttgaatcaa gtagtgagtg attttcctga gttgaaaatt gtatttgagc atatcactac
    17881 taaaaatgct gttgattttg ttttagcaag tcatcataaa atagcagcaa ctgttacacc
    17941 acatcatctt ttagctaata gaaatgatat gcttgttaat ggtatccggc cacattattt
    18001 ttgcctacca gttttaaaga ggagaaatcc acaccaaata gcattattag acgttgtaac
    18061 tagcggtaat gttaagtttt tcttaggtac agattctgcg ccacatatga agaccgataa
    18121 agaatctgct tgtggttgtg ctggtatttt taatgcacat tgcgctattg agctttatgt
    18181 aatggttttt gaacatcaaa acgcactaga taagttagaa ggatttgcct caaaatttgg
    18241 tgcggatttt tataatttac cttataataa aaagattatt acacttaata agaaagattg
    18301 gactatacca gcaagttatt cttttgcaca tagtaatatt gtgccattta tggcaactaa
    18361 aacacttagt tggaaactgg tttaaagtag aatataaatt ttcttgtttt taacgctttt
    18421 tttatctttt atattatgat tactactatt attaaaagtt ttgtatttat ttttatcaat
    18481 atttttatac tattttatta tgaactatat aaagatatat ttcatctagt acaggtatat
    18541 tgaaatagat aaattaattt taatacaata tacattattt tgagtaaatt ttaggttgaa
    18601 gaaataaata aattgagttt atttcaaagt agtttagtta acaaactata agtagtactt
    18661 ttatgcttat ttgtaaaatt aaaaaggttc taggaattta tatattctag ggataattga
    18721 atattgtaaa ggtttaaata agttattaac tagtaaaaaa aatttaaaga aaattgttca
    18781 gagtccaaaa aaaaatttag cgtttttaac gtctaatttt atttgttcct ttaatgctaa
    18841 aaaagaatta aatttttgtt catcacgaat tttgtatttg aatataacct tggtatattc
    18901 accataaact tgtttgttaa agtcaaataa aaaaacttct aataagattg tttcaccccc
    18961 aactgttgga cgttttccaa gattacatac accattgtaa attttaccat ttaattctac
    19021 gttaactgcg aatataccta atagtgggct gatcttcctt ttaataggaa tattgattgt
    19081 gggaaatcca attgttctac cttgtttttg acaatgaatg attttacctg aaattgaaaa
    19141 ttttcgtcct aacaactgat ttgctaagta aaaattacct tttttaagtg actgtctaat
    19201 ttttgaacta cttactctat caagattata aagcacggtt ggtgtttttt ctacctcaaa
    19261 attaaaggtt tgtaataaag aaaaatcacc tgtttggttg gatccaaaac gaaaatcatc
    19321 tccaactagg caaagtttaa ctttgagttt atctagtaat atttcatgaa taaaagtgtt
    19381 agcagtgagt tgtgaaaatg aagcattaaa gttaattaat aagtgttcat ctactccaag
    19441 gcttgtaagc aaagcgtgtt tttgtttgaa actactaagt gtggcttgcg catgtccaaa
    19501 aaagtgttgt ggcgttggtg aaaatgaaac aatcactgat ggtaaattca taatttgtgc
    19561 tttattaact aatgttttga taattttttg atgtcctata tgtacaccat caaagttgcc
    19621 aatagtaaca acacttccta aatggggttt taaattttgt aaaccacgaa tgattttcat
    19681 aaatgttaat tttagtctaa ttaatggatg atattatcaa ctggttttgt tcttttgtaa
    19741 ttttagttat tggtttgtta ttctaaacaa ttagattgga tttagctatg ggctttaatt
    19801 tagtatatgt taagcatggt cattgatcta aagttttatt ttcagataca ttagtttgag
    19861 aagataatta ttaataatcg ttgctaatta actaaatatg ataaggatta tttagttttc
    19921 cttttgctgc ttgtcaggat agataataat gactaaatta gtcaaactat tttagtagta
    19981 gttttgagat ttagtgcact attttaaatt aagagggtca tttggattaa taccgttcat
    20041 aaatggtttt tcaatatctt catgagttgt ttggtaaacg caaccaatcc agttgttgat
    20101 aatgacatta gtggcgtttc cccaagtatt atctaaggtt tttttaatga gcttttcagg
    20161 aaaatttgaa atattaaatt ctgaggataa aagtttggtt ttatattcat tgagaatagc
    20221 tttactttgt tcggttaaat aatgttcagg gaatggtgga tagttattcc ttgttttttt
    20281 taaataggaa ataatatcgc gcttgtattc ctttaatagg ctaatagtat cgtattctgg
    20341 atggccttga aaaaatacaa tccttaataa atcttcacta actcctaagt gaacaccgat
    20401 tttactttca actaaaattt taactccagc agcattaaat tgtttttttg aaatttcatt
    20461 aaaacgagaa tgtggaacgt taaaacgtgt gttaacgccg ctcattaaag ggtgttgtcg
    20521 gtctagtatt tggtgtggaa atacgcccca acatttttca ccaatggctt tgcgtttttg
    20581 cccatatcta aactctaaaa cagcgtgagt tgctaaacat gagcatagtg ttgaagtaac
    20641 atggtcgtac gaccaatcaa caacttcttt taattcttca tagaaaggtg ctttttgtaa
    20701 atcttcttgt tcaatatgcg cacctgtaat aattagtgca tcaagtcctt gtgctttaat
    20761 atctgtaaaa gtttgataat gttgtttgat atgtttgttt gcttttttac cacgtttgat
    20821 tgatggtagt gtgaatggat gtaaataaaa ttgtgcaatt tggttagaat gtccaataag
    20881 acgaaaaaat tgacgttcag ttgcctcaag tgctgcgtct ggcattgtgt ttagtaagcc
    20941 aatatgtaat tcacgtatgg tttggttatt tgccctgtct tttgacaaaa tagtttcacc
    21001 ctcatcttta agacgtgaga aagaaggtag gtttgaatgt gcaattaggg gcattagttc
    21061 atcgctctat agataagttc aaatatttcg ttggcacttc tacattgata taagtcttca
    21121 ttatcaataa tgtaaccata tttttttgca attgcttcat attttggttt gcggtgttca
    21181 agtaggcggg gaaataccca gcgtacaaac ttgtttgggt tgatttgtgc aatataaatt
    21241 aattgatttt cctggaggta aatgtctaat tcatgtttta agaaattagc ttgataatat
    21301 aagggttttg gatgtgtctg tgcacgttta atcaaagcta tctcgttagt tttgctagcc
    21361 ctaatataga gaatcaccgt gttgtcagat agggtttgat atacttgttc attatctaat
    21421 tcacacaaac taccacctgc atcattaata aaatgattaa atccttgtgc tttggctttt
    21481 tttataaatt ggggtacatc aagcatggtt tttatttctg cgtttaagtg cattatttga
    21541 cgagcaataa aagtgtcaat ggatgtacca cctagttcag gattgcctgt ttttcctaaa
    21601 aaagtagata ctgatgataa gttatcaaaa gtaatgtgat tttggatact aatcgattct
    21661 ttatctagta agtctttaag ccatttatct tgtttaacgt ggtttttaat gttccctaaa
    21721 attttatcat ttaaatactt agcacctata cgataatcac tagaataatg aaagtattta
    21781 tcttgatggc taagaagttt tgctaagtgt gtttttccaa ctcctgacat gcctaataga
    21841 gttagacgtt tgtgattaga gtttttaaat tcgctgaatg atagtttcat gattttgatt
    21901 tttcatcaaa tctgttttta taacaaacca tcttttttaa acatttcacg aataccccta
    21961 attgcttgac gggttcggtg ttcgttttca attaatccaa aacgtacgta ttgatcacca
    22021 taactaccaa agccaatacc tggtgataca ctaatttttg caattttaag aagtttttta
    22081 gtaaattcta gagagcccat gtgttgatag aattcaggaa tttttgccca aacaaacatt
    22141 gtagctttag gcggtgtaac tatccatcca attgagtcta aaccattaca gagtacatca
    22201 cgtctatctt ggtacatatt agatatttct tttacacagc tttggtctcc ttctagtgct
    22261 tcaatagcag caatttgaat aggggtaaac ataccataat ctagataaga tttaatttta
    22321 gcaagtgcac tgactaaggt tgggttgcct accataaaac ccacacgcca acctggcata
    22381 ttgtagcttt ttgaaagcga aaagaactca acagaaatct ttttagcccc ttctacctgt
    22441 aaaatacttg gtgctacgta gccatcaaat acaatatctg cgtaagctaa atcttgtact
    22501 acccaaattt catgtttttt ggctattttg ataacttttt caaaaaaata taattcagca
    22561 cattgtgtgg ttggattaga tggataattt aaaactaaca tttttggttt ggacaaagta
    22621 tttttaatag agtgctctaa ttctgttaag aaatcatcat ctggaccaca aggcacatac
    22681 tgaatctttg cacctgcaag cacaaaccca tatgggtgaa tagggtaagc agggttaggc
    22741 actaatactg tatcgccact gtctacaatc gcttgtgcta aattatatag cccttcttta
    22801 gagccaatag taacaatagc ctcagtttct gggttaatat caacattaaa gcgattttta
    22861 taccaattac taatcgcttt tcgtaaccgt ggaattcctc ggaaagtagc atatcgatgt
    22921 gtatctttac gtcgcgttgc ctctactagt ttttcaacaa tatgattagg tgttggttgg
    22981 tcaggattac ccataccaaa gtcaataata tcttcaccac gagcacgtgc cttggccttt
    23041 agtttgttag taactgcaaa aacatagtca ggtagtcttt ttattcgtgg gaaatcatta
    23101 ttcattgttg tttagtttgt gttagttaga atagattatt gaatggctaa taattcaacc
    23161 tcaaaaatta gcgtggtatt ggatgggatt agattacctg aacccatctc gccataagct
    23221 agttttgagg ggatgatgag ttttcgtttg cccccaatac acatgccatt aataccttgg
    23281 tcccagccga ggattacttg tccaactcca agtttaaagt taaaagtttc atttctatca
    23341 acacttgagt caaatttttt accatcaata aaccagccag tatagtgcat tgagataaaa
    23401 tcacctgctt tacaagcagc tcctgtgcct atttttaaat tttgtatttc taaatcttcc
    23461 atatttattt ttcctaataa attattgtaa tatgatgtga gctaaatttt ctaatattta
    23521 acactcccgt attaagtaat aaatattgcc ctttaatacc ttgtaaaata cccttaattt
    23581 taggggtttt ttcaaaattt aatgagctaa ttttgttagg gtattttatc acagggtagt
    23641 taattgttaa aacttcatta tccagtacaa ttgcgctcaa atcactaatt aagtggggta
    23701 tttttttaag taaatcattg ttggtttttt ttatgttagt ttgctctatc tcgtttttga
    23761 gcatttttcg ccagttagtt ttatcattga cataattttt aagtgctacc tcaatttttc
    23821 ccgatttaag ccgattatca atctcaagta tggctagtgc aacaattgca ccttgatcaa
    23881 tccagcggct aggaatattg cttttacgag taataccaac ctttattcca gatgaattag
    23941 ctaaataaac aacatgtgga ttgaagcaat tatccagtcc ccattctggt tcacggcaag
    24001 taccaaggtg gtaatgacag gtttctggtt ttataataca caaatcacat cttgctaaac
    24061 tttgacaaca agaatagcaa aacccttgag aatagatttt attaatatgt tttttacaat
    24121 ttgagcaaac aatttcacca ttaaactgaa gactaatttg ttcacctact aagtcgttca
    24181 tatttagtaa tttattacca attggtagtt gatactgtac tatattactg tttaaatagg
    24241 tatgcatttt tttgataagt ccattaattt gcatggtttc taatgttgca ttaatcgttg
    24301 ctgaacttct ttgtatttat cagcggtttg ttgaatgatg gattttggta atgttggtac
    24361 agatatggtc ttatcccagt ttagtgtttc taaataatca cgtataattt gtttgtcaaa
    24421 actttttgga ctattgccta tttgataatc aatctttgac caaaaacgtg atgagtcagg
    24481 tgttagaact tcgtccatta aggttagttg gttgttttca tccaacccaa attcaaattt
    24541 agtatcggca atgataatac ctctttctaa ggcgtagtta ccagcgaagt tatagatttc
    24601 tagactaact tgtttgattt gttgtgctaa tcttttacct acaattttaa ctgtttgagt
    24661 aaaatcaatg tttttgtcat gctggttcat agtggcttta tttgatgggg tatagagtgc
    24721 agaggataat ttttcggcta agcgtaagcc tttgggtaat ttaatactac atatttttcc
    24781 taaggtttga taatctttcc aactagatcc tataatatat ccacgaacaa tagcttcaat
    24841 agcaataggt tttagttttt ttacaataat accacgacct tttattaggt ctgcttcttc
    24901 gttgtttaaa atgctatcaa gtggttcaag tgttagatga tttttaataa tatgtctggt
    24961 tttttcaaac cagaaatttg ccattttggt taggattaaa cctttgttgt taatgggttc
    25021 atcaaagatt acatcaaaaa cactaagtcg atctgtagta acaatcagca tacgcttatc
    25081 atcaatatcg taaatatctc taactttacc tttttgaatc agtggtagac ttaagtttgt
    25141 actagataat atcattagct tacgtgtatg aattatttaa tttaggtgtt attttaatca
    25201 attgtgtaac ccggcttgta aattatgata acttaaacca tggtaaaata acaaataagt
    25261 tgttatgtta ataaaaattc tcattatttg cgtacttatt cagcattcgg caattgcttc
    25321 aacattgtca aaaaacgcat tacggcttat caaaattggt catgaaattg gttcacgtga
    25381 tgttacgtta agaggacagt attttttgct aaaaagtgct tttgatttag gtgattttga
    25441 tgctatgtat gaagtttcaa aacaaattag atacggaagt aaattaatgg gatatgttcc
    25501 tttggaacgt gcagccaatg agattcttat taaattggtt cgtaaaagtt acgatccagc
    25561 tttatatgag tacgccttaa atttacttga tggtagtgat ggttttatta agaatgagtt
    25621 tttggcctta catttatttg aggagtcttt taaagttcat ggtaatgcta aatctgcatt
    25681 aatggcagct attatttgta atgaatcgct agtaccaggt actaaagaat tgaattatat
    25741 taatgagtta atcacatttg cgatattaaa taatgttgca ggcgcacaag cgtatcagaa
    25801 tcaatacata agattggact atttatctga tctaaatcca cctagttggc gtatttgggt
    25861 tgatactcaa gttttaaatt agataaaatt ttattaattt tggttttaaa tttttttata
    25921 ttgatatgat ctatgttttt ttgtggaggt actttgtaag tgataggatt tcttcttttg
    25981 cctttatgat gtagctcgta atgtaagtgt ggacctgttg agtgacctgt tgaaccgaca
    26041 taaccaatta tttgaccttt tttaatcttt ttatctttgt ataggttgtt ggcatatttt
    26101 gataagtgtg cataaacagt agtgtaatca aagtcgtgtt caatgatgat gactttacca
    26161 agtgaacctt ttctaccttt ggtagtaatt attccattgg cagtagaata aacgggtgtg
    26221 ccatgtttag ctgcatagtc aactgctcga tggggacgcc aagtttttaa tattgggtga
    26281 taacgcttga gttgaaattt ggaactaatg cgcttgtatt ttagtggtgc tcttaaaaaa
    26341 gaagagctta gagaatggcc aaagcgatca aagtaactag tatgtccatg tttgtttttg
    26401 tatgcaaagg cctcaataga tttattgttg ataatgcttt gataaatgat agctgctggt
    26461 tttatacttc cattactaac aatgatgaat cggtcgcctt ttttaagatc agtatgaagg
    26521 tttaattgcc atgaaagtgc tttaataaca gagttaatag tactaaaact aatccctgct
    26581 ttttgtgcat caacaccgaa ggaatgattt atattaacta cagttgtaga tgaattgcta
    26641 agtgtttttt tgggttgttt gttgagaacg gtggaaaagt aattaccatt aagcacaata
    26701 tctagattaa ttatgttatt tagttggtaa gttaaagatt taaaatgttg atttttatgt
    26761 aatctaatga ttaatttgtg accaatgttt aactggttga gttttttatt atgtttattg
    26821 gcaataagta gattgataag taatcgatta gaaagcccaa gtttggaaaa atattgactt
    26881 agtgaatctc catgtttaat agtgaagtga tatgtattgt tgtcagaata agcaggagtg
    26941 agtatcatgc taaaaaacat aagtattagt agggtaattt tgtaaaatct acccatactg
    27001 tttgataatt tcatgagcta tttcacgagc aataagatca ttgttaatta cttcttctaa
    27061 agagtttagt gttgtgtgtt tcatagtgct tagtgtttgg tcgatgattt tcggtatatc
    27121 taaaaaacta atttggtggt taagaaaata tttaactgca atttcattag ctgcattcat
    27181 agtaatcatg gcgttaccac ctttgttaag tgcttcaaat gctagtttaa gacaagtaaa
    27241 tttttcaaaa tctggttggt aaaattctaa ggaagctgtg ctagttaagt caagttcaga
    27301 aacgccagag ttcatgcgtt ttggataact cattgcatat gcaataactg tacgcatatc
    27361 tggatttcct agttgagata gtgttgaacc atctttgtaa aagactgatg aatgaacaat
    27421 gctttgtggg tgtataacca catcaatttg ttttggtgtg agtgaaaata aataatgagc
    27481 ttcaattact tctagtcctt tgttcatcat agtagcagaa tcaactgaaa ttttacgtcc
    27541 cattgaccag ttcgggtgtg cacaggcctc atctggagtg atggatttaa attggctaat
    27601 tggtgtgtgt aagaacggtc caccactagc agttagttga attttattta atcctgattt
    27661 gccacttttt aggcactgaa aaattgcact gtgttctgaa tcaacaggaa tcagttcggc
    27721 attaaattct tttactgttt tcataaaaat atcacctgct aatactaatg attctttatt
    27781 tgcaagcata attctcttgc cagctttggc accacaaagt gctgaggaca taccaatagc
    27841 gccgacgata gcagccataa catagtcagt atcttgatga gtaacaattt tatccaaagc
    27901 ttgaacacta ctaagtactt ggatatcagt agtgatagca tttgataatt tttcagcaga
    27961 ttgttcatct accataatgg cataacttgg ttgatattta ttgcataact taatcatttg
    28021 tttccagtta gtgttagcgc ttagagcaaa aatattaaat ttatcaggat gtagatctac
    28081 cacagatagc gtggattttc cgatagaacc agttgctcca agtaaggtta tgtttttcat
    28141 attaagctaa gtcctagcaa gaagaatggt gctgttgctg tgagagaatc gattcgatct
    28201 aagattcctc catgtccagg aaggatttgt ccactatctt taatgtttga gatacgttta
    28261 aataagcttt caaataaatc acctaatact gatatattag caataacaac cgttaatagc
    28321 aaataatcta aatattgatt agttgctata ttttgattct gtaaaaatat catcattacc
    28381 actaaagcaa caacaatacc acctattacg ccttcaattg actttcctga acttaattta
    28441 ggtgctaatt tccatttacc aattgcctta ccaataaaat aagcaccaga gtcagcaccc
    28501 caagtaatca acattagtag taaaaaatat tcagatccat attgttgttt taaagtaatt
    28561 agcgcaatcc acataggcac taataacaat accccagtta tgatacgaac aataagtggg
    28621 tcaaaccaaa aattagtttt gcttggataa cttagtaccc aatataaatt aattgtccac
    28681 cataaaacag ataagtaaag tataaatgga ataatttggg tatttttttg aataataagt
    28741 gcacatatca caatactaaa taccaatagt attctagcga ttaagcgcct aaatttaatt
    28801 aaacgggaga attcccatgc gcctaatgct gtaaaaatca agagtagttg ttcgaagtaa
    28861 taattaggca tagcgaatat tgcccaaatt attagcggtg ctaaaataaa agcggttatg
    28921 attctttttg ttagcataat tttttcttta aagtcttgta ccaaaacgtc gattacgatt
    28981 attaaagcta ttaatggcct tttctaattc agatttatta aaatctggcc atagtgtttt
    29041 tgtgaaataa aattcactat aagcaatatc ccacaataaa aaattactaa ttctaagttc
    29101 accactggta cggattaata aatcgacatt tggttcattg gctaatgaca ggtattgtga
    29161 aaagtttttt acattaatat cattggcttt tatgtctcca gcaacagcta ctttagctgc
    29221 tttaattgct gcttgagtaa tatcccattg gccgccataa ttggctgcaa ttattaatgt
    29281 taaaccagta ttactagcaa gtatagcttg tgtatcaatt gctacttgtt gaattttgat
    29341 aggaaataaa gacatatcac caattatttt tagcttaata ttgtgtttat tgagtttttt
    29401 tacctcttgt tgaagcatgt caagaaataa tttaaacaat aaagagactt ctttagtcga
    29461 acggttttta ttctcactac taaaagcaaa taaggtaagt gttttaatac tacgtattga
    29521 acaagcttta acaacattac gtactgcttg aattccttgt tgatgtccta gaatgcgggg
    29581 taaagagcgt tttgatgccc aacgaccatt accgtccatt ataattgcga tgtgtttaag
    29641 cgtactcata acaaagttag attataccta tagcattaca aacagtcagc aaacacagtt
    29701 aatatagaac tgatatacgg taaaatttat gattatgagc ttagcaataa gaattattcc
    29761 ctgtcttgat gtatgtgatg ggcgtgtggt taaaggtact aaatttattg atattaaaga
    29821 tgcaggagac ccggttgaag tggctaagcg ttatgactta gagggtgctg atgagattat
    29881 ttttttagac attactgcat caattgatgg tagagatacc atgatacata tggttgaagc
    29941 aatcgccgag caagtattta ttccattgac tgtaggtggt ggtattcgta aggcggcaga
    30001 tgtacgtgct atattaaatg caggagcaga taaaattact attaattctg ctgctatttt
    30061 taaccctaat ttaatcaacc agttaagtaa agaatttggt tcacaatgta ttgtcattgc
    30121 tattgatgca aagaaaattg attataataa atggggaata tttactcatg gtggacgaaa
    30181 atatacaggg attgatgcta ttgagtgggc aaaaaaaatg acttgtggtg ataatggtgc
    30241 tggtgaggtg ttgcttacct caatggattg tgatggtgtt aagacaggtt ttgatttgtt
    30301 acttaccagg gcagtctctg atgcagtaga tgtacctgtt attgcttctg gtggtgtagg
    30361 aaatttagaa catttatctg aaggtgtgct acaaggagct gctgatgcag tattagcagc
    30421 tagtattttt cattttggtg aatatacgat acaacaagcc aagaaagcta tgcaagaaaa
    30481 tggtataaaa gtcagacttt agcacttggt tttttaattt cttggttttt taagtgtatt
    30541 atataagtac tttataagca taagattttt atgaattcta aaaaagaatt atggatatta
    30601 ttagcatctt ttgtgttgcc aattgctttt gggacggctt ttttttacct aagtcctgat
    30661 tcttttactc gtcatacgat taatttcggt gagtttgtta accctattat tgctactgaa
    30721 aaagaagatg tagtttttac agatatcaat cacaacctac aaggtttgtg gacattggct
    30781 tatgtaacca aacaatgcga tagtatttgt gtaaaagcat tgcacgatat aagaactgtt
    30841 cgaattttga tgaatgaaga catgcttcgt attcaatgtt tattgttaat gacaaataaa
    30901 gctaaagcta aagtgcaacc agcagatata ttagttggat actctattga gtcacttagt
    30961 cgacaattta atcagtttcc aaaaaatagt ttatttttaa ttgatccgct tggtaatgtg
    31021 atgttacgtt acgattcaaa acaattagaa gttaaacgtg tgattaaaga tttaaaacgc
    31081 ttgttgaagt attcacgtat tggctaatag gagataataa tgcctttaat tagtgactta
    31141 ttagctttat gtaaacttaa ggtggtggca ttgatattgt ttacggcagt ggtgggtatg
    31201 tttttagccg tacctgcacc gtatttacct aatgggttat tagtattaag cgcctcaatt
    31261 ggtattagta tggtagctgc ttcagcagca gtgtttaacc atgtggttga tgaacagatt
    31321 gatgctcaaa tgtctcgtac taaccaacgc cctttgccac aaggaagggt gagtaaaaat
    31381 caagcgttag tgtggggggt atttttggga tttattggtc ttggtatttt gcaattattt
    31441 gttaatatta ttactgttgt gcttacgttt atttcattaa ttggctacac tattgtttac
    31501 actttgtatc ttaaacgtgc aacaccgcaa aatattgtta tcggtggtgc agcaggtgca
    31561 acaccccctg tgctaggctg gacagccgta tctggtaccc agggtattga atatgcttgt
    31621 ttgttatttt taattgtttt tatctggaca ccgccccact tttgggcact agctatttat
    31681 cgggtcgagg aatataaaaa aatcgatatg cctatgttgc cagtaacaca tggattagcc
    31741 tataccagaa cgcaaatttt attatatacg gttttattgt tattagttag tttgttgcct
    31801 tatttatcag gcatgtctgg gcttatttat ttggtaataa ccattgcatt aggagttaga
    31861 tttctagtat atgcgattaa aatttataat aatccagatg ataaaatggt tgcttggagt
    31921 acttttatgt attcaattaa ttatttaatg ttgttattta ttgcactatt atttgaccat
    31981 tactggctaa tatcaccttg ggagattctt tagatgaaaa gattaggaca agtatttaaa
    32041 gcagttgtat ctgctatgat tggtgttggt aaaaaagaag atttagtaaa agattttgca
    32101 cgtactgaaa aacaaggacc atggccttat attattattg gtctaattat gacatttatt
    32161 tttattggtt taataatagc agttgttaag ttagtattac cataatcaag tgttttgatg
    32221 attacattaa gtgattgcta tttttttgtg taggttagag tttggttaat agtctgattt
    32281 atttaagaat gtagtatata tagcaataaa tagttagttg ttatgtttta taaaagtttt
    32341 atgtaccata gtaataatac taagtaacaa tagtaacgct atagtgttat gtaacactgc
    32401 tattattatt ggcaatgaaa gaacaacatt aagaacacca agtgtgattt gtattgttaa
    32461 tagaataaca cttaatatta aattaaacct taagtgattg taatttctaa ataaataaat
    32521 aagtaatagc atgaatatgg ttgttattaa ggcgccaata cgatgaagca cttgaatggc
    32581 agaacgtgcc gggttttcta atataccata ctcataatta gctcctaacg atccccaata
    32641 taatgcgtga gtaaaatcta gatcaggcca ccatttgttt aaacaagttg gaaagtattc
    32701 accacaagat agcgctgcat agttagcact tgtccagcca cctagaatga tttgtaaact
    32761 tagtatggtt aatgttatta ataatacaaa tttatgttct tttaaaacgt tttggtaagt
    32821 agttggtgtt tttttttgat ttaagaacat ccaaacaagt aatatagtgg ttaaaaatcc
    32881 ccctattaaa tgtaaggtaa caatgccagg atgtactaaa aatgtgactg tccacatacc
    32941 aaatgcacct tgtaacataa caaaaaaagc gctaaatcca ggcagtttta atgattgttg
    33001 gtgttgtagt ttccctttta gtgctaagaa aaacagaata agtattgtta atccaagcgt
    33061 ggaggcaaca tagcgatgta gcatttcttt ccatcctttt acaatattta gtggacgaga
    33121 aaaaccttga atagtagtac cgtctttagc gtcaggtacg cttagttgac cataacatcc
    33181 tggccaatct ggacagccta acccagcatt acctaggcgt gtgtaagcac ctagaataac
    33241 aacaatgagt gctaaaataa ttgaaatttg cagtattttt ctaaacattt gtttgttaaa
    33301 acaacccctt ctctatattt atacaagtaa ttctaaaata gaataaaata cttctagata
    33361 agaaattaga gtattcctta ttgaattatt attctaactt gctaattaaa gatttataag
    33421 catgccaggt tgcatgtgct aatactggaa cagtaaccac catacctaaa aaatatggtg
    33481 ttaataaact agctaaaaca ataataccaa caattggcac ccatatcaac attacaattt
    33541 tatttgctaa tgcggtttta atactggtat gagcagctgt aaaggggtcg atattttggt
    33601 ctaataccat agggaaagag aaccagctaa tcataaaaga tatccaagca gtaacggtag
    33661 taaaaatgcc ataaatgact aaaaataatg gattattaaa gttgataata tcatctaaga
    33721 tagcttctat aattgtttga ttttgattaa caaaagtgtc ggtattgagt attgcataaa
    33781 taagaggtgt aaacaccatc cacataattg ctataataat taaaataata gataaaaaga
    33841 atgaaggata agagccgcca ttggctttga aggcagattt aataacggtt aatatagatc
    33901 taaaagaaag ctcttctcca atagataagc gttttgaggc atcatacata gccatggcag
    33961 aaataggacc aaatataatt accaccatag ctaataaagg tgctgcaata tcgctaagtg
    34021 tgggcgagtg tgataaaaaa tcccagtaaa aataggtaaa tgaagtaaat agtgtgccat
    34081 aaaataatgc caatgctggg cattttgtaa aatcttccac gccttttttt aaccatgtaa
    34141 agggagcgct gtaactaatt ttcttaatat aaactttttt gtttatactc ttagtcatcc
    34201 ggggtatttg tagcattttt aatctcctga atttgatgtg taatatcatt catattaaaa
    34261 cagacctttt tatacctgtc aagaaaataa gttaaatatt ttgacttaga attaaggaaa
    34321 tttattatta tttgtgaatg agaaaaaata attgtgtatc ataagtataa attttcaata
    34381 cactagtgta ttgaaaatta tagtattttt atatagggga gaaatttatg agcaaattga
    34441 cgtcttattt aggtggtttg attgcaatag tatcagtaaa tgcattttct gaatatgatt
    34501 tgaatatgac acgtggagtt acctctgtta gtcgagatat ttatgggtta cacatgatgg
    34561 tgttttgggt ttgtgttgct attgctatta ttgtatttag tattatgatt tactcattga
    34621 ttgtacaccg taagtcgcaa ggtgcggtag ctgcaaattt tcatgaaagt acaaaagctg
    34681 aattgctttg gacaggtatt cctattatca tcttagtatt aatggcaatt cctgcttcaa
    34741 gtacattgat tgatttagaa gatacttcta aagcgcaaat gaccattaag attacaggcc
    34801 atcagtggaa atggcaatac gattacccta aggaaggtat tagttttatt tctaacctta
    34861 aacaaaattc taaagacgct atctactcta aaaataaaca tgagaattat ttgttagaag
    34921 tggacaataa tctagtgtta ccggtagata cttctattcg tttcttaatc acctcaaatg
    34981 atgttattca taactggtgg gtacctgatt ttggcgtgaa acaggatgct aacccaggtt
    35041 ttattaatga tgcgtgggca aagattgatg aaataggcac ctatcgtggc cagtgtgctg
    35101 aactttgtgg taaagatcat ggttttatgc ctattgtggt tgatgtagtc tccaaggcag
    35161 attatgctca atgggtatta aagaaacaga taactaaagc agcaaaactt actcaatcaa
    35221 gaaaaacttg gagtgaaaag gatctaacaa gcttgggtaa aaaagtttat aacacaaatt
    35281 gttctagctg tcatggtatt actggaaaag gtattcctgg tatttttcca gcgcttagag
    35341 gtagttctgt tgcaactggt gatatcaaaa atcatatagg cattgttttg catggaaagg
    35401 ccgggactgc tatggctagt tataaaaata tactgggaga tgctgatatt gcagcagtaa
    35461 taacctttga aaggaattct tttggtaatc aaatgggtga tttggttcag ccatcagata
    35521 ttaaatctgc acgttaattt agaataatta aggagaaaca atatgacaac aataactgct
    35581 tacactagcc atcacagtcc tgaaaaaggt ctgatgagat ggatcaaaac aaccaatcat
    35641 aaagatattg gatcgttata tttatggttt gcgtttatta tgctattagt tggtggtgta
    35701 atggcaatgg ttattcgtat ggagttattt caaccaggta tgcaattaat taatccacaa
    35761 ttttttaatc aaatgacaac catgcatggt ttaattatgg tttttggtgc aattatgcca
    35821 gcatttgttg gtttaggtaa ctggcttatt ccaatgatga taggagcgcc tgatatggca
    35881 ttgccacgaa tgaataattg gtctttctgg attctgccat ttgctggtgg tattttacta
    35941 agcacatttt ttatggaagg gggtgcacct gcgtttggtt ggacatttta tgcgccactg
    36001 tcaacaacat ttgcaccaga tagtaccgat ttttttattt ttgcagtaca tttgttaggc
    36061 ttttcttcca ttatgggtgc gattaatatt gttgcaacag tggtcaatat gcgcgcacta
    36121 gagatgaagc ttatggatat gccattattt gtatggacat ggctaattac ctcatttttg
    36181 cttattggtg cgatgccagt acttgcaggt gcggtaacta tgatgttgac agatcgtaat
    36241 tttggtacgg cattttttga tgcagcaggt ggtggtgacc ctgttatgtt tcagcatatc
    36301 ttttggtttt ttggtcatcc tgaggtttat attatgattt tgccagcatt tggcgtaatt
    36361 tcacatgtta ttccaacttt tgcacgtaaa cctttgtttg gttattcatc aatggtttat
    36421 gctacagcat cgattgcatt tttatcctat attgtttggg cacaccatat gtttttaact
    36481 ggcatgccag ttgctggtga gttgtatttt atgtacgcta ccatgttaat tgcagtgcca
    36541 acaggtgtta aggtgtttaa ctggatctca actatgtgga gaggttctat gacttttgag
    36601 acgccaatgt tatgggccat ttcatttgta tttttattta caattggcgg tttttctggc
    36661 gtaatggtag gaattgcgcc ggcagatatt cagtatcatg atacttattt tgtagttgca
    36721 cattttcatt atgttttagt gactggtgca ttatggtcta ttattgcagc aacattttat
    36781 tggctgccta aatggacagg taaaatgtat aatgaaactt tggcacaggt acacttttgg
    36841 tgggcagttg tttcagtaaa tgttttattc tttcctcagc actttttagg gcttgctggt
    36901 atgcctaggc gtattcctga ttattcgtta cagtttgctg attttaatat gatctcttct
    36961 attggtggct ttgcatttgg tacatcattt attctattca cctatattgt tattgattgt
    37021 attcgtaatg gtaaaccagc agatgctcgt ccttgggaag gcgctaaagg tttagaatgg
    37081 accttagagc caaaggcaca gtatcatagc tttaataaac caccaacaag agagttgatt
    37141 aagcaagaat ctcagaactc ttaatgaaaa ataaaaatca acaaggtgtg gtaattactg
    37201 tagtaattac cagcgccatt gcagtaggtg tgtttatagc aaccattgta ttgtatggtt
    37261 gatataagtg ttcggaaaaa aataacaaaa acattttgga taaaattaat tttatcacca
    37321 atattaatgt ttgcctttgc ttatgcaatg gtacctattt acgatgtatt ttgtgaaatt
    37381 actggattta atggaacaac aggtagaatt aatagtgaac aaatatatgc tatagatgaa
    37441 tcgcgcagga ttgaagtaag tttttttgct atgacaatgg gggggtttcc ggtacagttc
    37501 agacctaaga taaattcaat ggaagtaata cctggtaagt tttacactac tagttatatt
    37561 gctaagaata atactgataa agttgttatt ggtcaagcaa ttcctagtgt tgctcctaca
    37621 gaagcggcat tgtattttaa aaagttagag tgtttttgtt tcaataaaca agtgtttgaa
    37681 ccacatcaga agatagaaat gactttaaga tttgtgattg agccagaatt agacaagcgt
    37741 attaaagacg tgagcttatc ttataatttt tttaagatta aaagttaaaa aaaggggaga
    37801 gaaatatgaa tgaacaagaa tattatgtgc caagtggtac ttattggcct attattggtt
    37861 caattggtgt tgctacttta tttgtaggtt ttgctaatca aatgcatggt gctagttggg
    37921 gtgcttcaat tatggcctta ggctttagta ttttggtatt tatgatgttt ggttggtttg
    37981 gtcaagttgt taatgaaagc actagtggta tgtataacag tcaagttgat cgctcatttc
    38041 gctggggtat gagttggttt attttttctg aagtgatgtt ttttgctgcc ttttttggcg
    38101 ttttatttta tgcaagacaa ttatcagttc catggctagg tggttcaggt aataactttt
    38161 tcactcctga tttatggaat ggttttagtt caacatggaa acaaattgct tttagtacac
    38221 ctggtttaat cctacaatca ggtacagcaa tttctgtgcc aagacaatta gttgatgctt
    38281 gggggctgcc agctttaaat acagcattac tgcttttatc aggtgttact ttaacttttg
    38341 cgcatcatac actgcgtaat ggagatcgta ataaaattat tggatggttg gttgctacca
    38401 ttgttcttgg tgtgttgttt ttaggatttc aaattactga atatggccat gcatatcatg
    38461 atggtttgaa gctaacttct ggaatttatg gctcaacatt ttatatgtta actggttttc
    38521 atggttttca tgtaacagtt ggtgtaatta tgttaactgt tattctttat cgtgtacaaa
    38581 aaggacattt tagtgcagat aaccactttg gctttgaagg tgttgcttgg tattggcatt
    38641 ttgtagatgt agtgtggttg ggtttattta tctttgtgta ttggttgtag ttagttataa
    38701 aattgataaa aatattttat atttggtttt ttatcctatt tcataggaaa agctaatgac
    38761 acaaatcatt atagttatca ttattatcgc tattttaata gcactaagta taagtttact
    38821 gggtatgctt agaggtggga aagctggttc gaataaaatg tttaaatcat tagtaatacg
    38881 cgtggtattg tcgttatctt tgtttattat cgttatgttt tttgcttata tgggttggat
    38941 agaacccaat ataattatga tggatacatt ttcttttcag tgattaagca tactattttt
    39001 attcctatta ttttaatatt cttaattatt tatggattaa tatcgttagg attttggcag
    39061 attgaccgtg ctgatgagaa acgtgttatt gagaataaga ttatactagc gcaacaaaaa
    39121 ccagttcagt tgataacaaa tgtaaaagag ttgttgaata aagagtatca tcaggtgcta
    39181 ttaaaaggtc attatgacac tgataaacaa tttatttatg acaatcaaat tgttaatggt
    39241 aatgctggtt attatgtact tacacctttt gtattaagta gtaaaactac catattggtt
    39301 aaccgtggtt ttgtaccttg gaatggaagc cgcggtcaat tagtgaatat taaggtagat
    39361 aacctaacaa gagttattaa agttagactg gttaagcctg ttgagcgtat taaacttaag
    39421 caagaattaa tcacatcaaa ttttcctgta ttaatacagt ctttaaattt agacgagtta
    39481 tctttgttat ctgattatca aattgttgct atgttagcgc gtcttgatat tgaagatagt
    39541 gatggatttt ttaggcaatg gcaatctttt tatggtagtg tgaataagca cttaagttat
    39601 gcattgcaat ggttcttaat ggctttagtg ttaggtatta tttctttaag attatggatc
    39661 aagaaaaata aaaaaaattg atctatatca aaagagcatg atgtggttga ctgtatcata
    39721 agtgctagtg tagaatttga gcctattttt taatataaag aactaggttg ttaatctaaa
    39781 aatatagagg actattaatg aatttaacag aaaagtatga tttaggtgtt gttaaatggt
    39841 ttgctattat ggcaactgtt tacctagtaa taggaacact gctcggtgta tacattgctt
    39901 ctgaattagc tttcccattt cttaatgatt taggtacaga tttaccttat tttcaatttg
    39961 gtcgattaag acctttgcac actaattctg tgatttttgc ttttgctgga tcagcactaa
    40021 tggcgtcagc tttttatatt gtacaacgca ctaatcaaac ccgtctttgg tctaataaaa
    40081 tggcttggtt tacattttgg tcatggaata ctgtgattgt tttagcggtt attactctac
    40141 ctttaggttt gacacaatct agggaatatg cagagttaga atggccaatt gatattttga
    40201 ttactttagc atgggtttcg tatctatata attttattat gactatttat attcgtaatc
    40261 gtaataaagt accacatgtt tatgtggcta attggttctt tatgggtatg atggttatgg
    40321 ttacttatct tcatgtgatt aacaatttat ccattccagt gagtgcgttt aaatcttatt
    40381 caatcttttc tggtgtacag gacgctatga ttcagtggtg gtggggtcat aatgctgttg
    40441 gatttttcct aacagcaggc tttttaggta ttatgtatta ttttgtgcca aaacaagcac
    40501 agcgtccaat atattcttat cgtttatcgg tgattcactt ttgggcattg atgtttggtt
    40561 atgtttggtt aggtgctcat catctacaat atacagcatt accggattgg gcaggttcat
    40621 tgggtgcaac aatttcatta gctatgatta ttccatcatg gggtggtgcg cttaatggta
    40681 ttttaacgtt atcaggtgct tgggatcgtt tacgtgaaga ttatattcta cgttttttga
    40741 ttatgtcttt agcattctac gccatgagta catttgaagg accggttatg gcggcgaaga
    40801 cagttaatgc cttgtcacat tatacagatt ggacgattgg tcatgtacat tctggtgcat
    40861 taggttggaa tattatggtg gcagcaggtg ctatatatca catgattgag aaaatttata
    40921 acgttaaaat gtcacaaaaa ctcttaggta ttcatttttg gatacatacg attggaacag
    40981 tggtttatat tgtagcgatg tgggtgtcag gtattatgca aggtcttatg tggagagcgt
    41041 atgatgaata cggaacattg gcttatacgt ttgctgagtc agtatcagca atgcatcctt
    41101 attatgttat gagagctaca ggcggcacat tggtactatt aggcgcaatt atcatgttaa
    41161 ttaatattgt gacgactatt cgtagatcag gttctggtca aatagctaat gtataaaaag
    41221 gaaatgaacc atggtaaata gaaacgtaaa agagagttta caggttaaat tagagaagaa
    41281 tatttttggc atgtatttgt ttatggctct atcagtatca ttagctggta ttgtagaaat
    41341 tgttccttta tttaccaatc ctgaagcggt taaggacgaa gtgattgtag ctgatgggag
    41401 tacaaaaagt ttattatggc ttcgttctaa aggtcaaagt ttgtctgatt ggaagcctgg
    41461 tgatggtgta aggcctttaa ctgctttaga attagcgggt cgtgatattt atcagcgtga
    41521 aggttgttat ttatgtcact cacaaatgat acgtccattt agagatgaga aagaacgtta
    41581 tggccatttt tctttagcgg tggagtcaat atatgatcac ccatttcagt ggggatctaa
    41641 aagaacaggc cctgatttag cgcgacttgg tggtaaatat tctgatgaat ggcatatttt
    41701 gcatttacgt catccacaag cagttgtacc agaatcagtc atgccaaaat atcgtttttt
    41761 agaaaatgct ttggtcgatg gtgatgtaat ctctacacac atgagcggtt tatctaaagt
    41821 tggtgtgcct tatacaaagg aagatattgt acaagctcca gccttcgtta agggaaagaa
    41881 tgaaatggat gcaatggtag cttatttgca atcattagga aatatgatca aatttgaaga
    41941 cggcgtgact tacagagagt aatgaccttg gttgataaat ttggtgctgt gatagcagtt
    42001 gttatatttt tattattagc aatttcttat ttttacgctt ttagaccaaa aaataagaaa
    42061 aaatttgaag ccttgcgtaa ctttgtaaat gataaagatt gagttaagat ggaaaaaaca
    42121 atgagtgaac agaaaaattc tttcccaggt gaaaataata cagggcattt ttgggatgaa
    42181 gaaaatgata ttagagagct aaataatccc ccgccaagat ggtatatgtt ggcattatat
    42241 atgggtacac ttgctgttat agtttatacg ttttactatc caactattcc ttggtttggt
    42301 gagcataata aaggttttgc tagttggaca caaattagtg aaatgaatga aagcgttgct
    42361 aaattagaga tttatcgtga agaaaggttt gctgatattg agaaagctat tgctgaaaaa
    42421 tcattagaag aaattgtact tgatgatgaa ttaagaactt atgctattaa aacgtctaaa
    42481 gtattatttg gtgataattg ttcggcttgt catggtgctg ctggtcaagg taatataggt
    42541 tttcctgttt tagctgatga tgattggttg tatggaggaa aattagaaca aattagtact
    42601 agtattacaa gtggacgaaa aggaagaatg ccagcacgta tgttgggtat ttcagatgct
    42661 gaggctagta cgttagctac tttcttgatt gaaataggta aaggtaaaaa aggaaattct
    42721 gatcttgctt ctaaagcact atatatgaat aaaggttgta ttgcttgtca tgctcctaat
    42781 atgaagggca atcaattgtt aggtagtgtt aatttaagcg acggtattta tcgttttaaa
    42841 gcagatgatc aacatgcgtc aattgtacgt ataattctac acggtgtaaa tcaagtaaac
    42901 gatccattaa cacaagacgc cgttatgcca tcatttggcc attcaagtat tatcaatgct
    42961 ttgcaaatta aaaaacttgc tatttatgtg catcaattag gtggtggtgt ttctgttaaa
    43021 taaaatactt aacaatcctt tatactatat ttcaaggaac tagtaatatt tttttattta
    43081 aaagctaatt tttttttaaa aatttgttat ctttgtaggt ataattctat cttcaaagcc
    43141 gaagtagcat agttggtagt gcaactgatt tgtaatcagt aggtcgccag ttcgagtccg
    43201 gccttcggca ccatattgac gagtaggact tataatattg tcataatcag gggttgtatt
    43261 tctattttaa aattgtgtat cctatcctcc ttattttttg ctctatatat aagaactctc
    43321 taggagaaaa atatttttta attattttta gatatagtta taactatgat agataaggta
    43381 aattatattg gattgaaagt gatgagagag gttatccatg aatattttta tattaataat
    43441 ggaatatgtg taaacagtca aaaaagaaag taagattaaa tctatttatg agaaattaag
    43501 ttatatcaca attagagtaa ttttatcaaa atctagacat tctcttttac tacatatcaa
    43561 tatatcaata ctagttttat tagtagttgt atatagactt aaatttaatt aatacctaat
    43621 catatagaaa gactattgta tatcaaaccc tgttttaagg tttagttcaa aagcatttga
    43681 ttcaatattt ggattaataa ttattgaatc aaatgttagt aaaattgttt gatttagttt
    43741 attattaaga ctaatggctt tcagcatgtt atcttttagg ccaaaattta attggttagt
    43801 ttgttgagtt ttataccaat taattttatc ttttgtgtat atatattggg gtatatgatt
    43861 gctatcgata ggtcgattaa taaaccaata taatggagtt tgtgttaagt tagttgttga
    43921 tatcaaatta gcttgttcta attcaacatc aattagccac agtttagtat tatttaacag
    43981 tagtatttgc tcatttggca ttagcttatg ccaagttgtt gcggacgttt aaataataac
    44041 gtgccagaag atttggttaa tagagtacct gtgttgttat aggtatgttg tgtaaagtta
    44101 gcacttaggc gttcaaatga accaaaaaaa ttagagaaat catagttact attggcaaaa
    44161 ctagaaaata caagcattaa agtacttata aatttagtca ttagtagtta taggtatagg
    44221 tgctaatact ttgcgatttc cagcgctatt catactgctt actataccat tagcttccat
    44281 gtcttcaata ataagtgctg cacggttgta accaattcgc atacggcgtt gtaggctaga
    44341 aattgaagca cgctgtgata aagttacaat tttcacagct ttattatata aaacatcaag
    44401 ctcacatgat atgtttgata ttttatttaa gtcttgtaga ttatttgatt tactattaat
    44461 attaagaata tcatctagat aattagtttc atggttatct tttaaaaaat taaccacgcg
    44521 ttcaatctca ccatcgtcaa caaaggcacc atgtacgcga ataaggtgtg acatacctgg
    44581 tttcatatat aacatatcac ccataccgag taattgttca gcaccacttt ggtcaagaat
    44641 ggtgcgtgaa tcaacttttg aagagacttt gaaagcaata cgtgtgggta tattagattt
    44701 gattagacca gtaataacat ctacacttgg acgttgtgtg gcaataataa tgtgaatacc
    44761 tgcagctcgt gatttttgtg ctaaacgtat aataagtgcc tcaacacgtt tagctttggt
    44821 acgatcttct tgggctagtg tgccaagcat atcagcatat tcatcaataa ctatcataat
    44881 cataggtaat gcttctaact cagttgttgt tttactttca ttagtagtat tttgattaaa
    44941 taacggataa aataaaggtt ctttcttatt tttagatttt tttatctttt tattaaagcc
    45001 ttcaatatgg cgcactccaa atttagccaa taatgaataa cgacgttcca tttcattaac
    45061 acaccagtac aaggcagaag ctgcttggtt catatctgtt acaacaggtg tgagcaagtg
    45121 tggaatgcca gcataacaag ctagttcaac aattttaggg tcaatcataa taatacgtac
    45181 ttcttctggt ttagctttga agagcacact taggatcatt gtatttagtc caattgattt
    45241 gcccataccg gttgcaccag caacgagcaa gtgtggcatt tttgttagat tggtaataat
    45301 tggaataccg ttaatatctt tacctagacc tagggttaag gcagagtcag atttaataaa
    45361 attttcagaa gaaaaaattt ctttaagatt gatgatttca cgttgtgtat ttgggatttc
    45421 taagccaata acaggttttc cggggataat atcaacaata cgtacacttt taactaataa
    45481 agcacgtgct aagtctttat taagatttat aatttgacta actttaatgc caggagcaag
    45541 tgaaagttca aattgagtga cgacaggacc aggggtgact gtggtaacta aaacatcaaa
    45601 accaaaatct ttaagtttta cttcaacttg gcgtgacatt ttttctagta tttctttaga
    45661 gtatccagtg gtgttgatag ttggttcatc aagtaagtct acatttggca aaccagttat
    45721 ggttatcgta ttaaatagat tagaggaaat aactttttta aaacttttat ttggtttttc
    45781 cttgcttctt tttatttcgg taagtatgct agttttagta cttgattgtt taatgggggt
    45841 agaaactttt atagttttaa cttgtgttct aatataacgc atttttttaa gaagattatt
    45901 taacatatta ttagtaaagg agaaaatatt aatccatgaa gaactactga caatgctaaa
    45961 actaatcatt ataatactga gataaataat tagtgatgca gaaccaaata aaacattaaa
    46021 ataacgatgt atactaatac caatatagcc accagatgcg cctatatctg taaagttttg
    46081 aactaaaaat gcagcactaa aagtaattag tgtcattagt gaaataaaac gaatagcaat
    46141 tgttaagtat tttaactttt tctgttcagt gtttttgtgg attttccatc ctaaccatat
    46201 tagtgagact ggtattaaat aggcactata acctaaatta gataaagaga tatcgcttaa
    46261 atatgcacca aatacaccag caaggttagc aactggtgca attagagtaa cgttacctga
    46321 ccaagggttt tcattagcag aataagtcac taatgcggat aaaaaaataa gacctatggt
    46381 acttaaaaaa ataaatagta tttcactagc tattttagta cgaggttttt gttggtatct
    46441 ttttgtactt atttttttat tctttttcaa ggtggtttat aatatctcga atgtattcat
    46501 aaagtataaa gtattcatat gagtgaaaat aaacattgta aggtattgat tattggttca
    46561 ggtcctgctg gttattctgc tgcagtttat gcagctagag ctaatcttac tcctgttgtt
    46621 gtgagtggta tggaacaagg tggtcagcta atgaatacta ctgatgtgga taactggcct
    46681 ggagatgatg ctggtgttca aggtccagat ttaatggcac gtatgaaaaa acatgctgag
    46741 tattttgata cacaagttat taatgatact atcatatcag ttaattttgt caaacgcccc
    46801 tttgttttaa aaggtgagat aattacctac acagcagatt cagtgattat tgcaacaggt
    46861 gcaagtgctc gttatttagg tttagaatca gaagaagaat ttaaaggaaa aggtgtatct
    46921 gcctgtgcaa cgtgtgatgg atttttttat cgtgggaaaa aagtagctgt gattggtgga
    46981 ggtaatacag cagttgaaga agcgttgttt ttgtcaaata ttgttgatca tgttactatt
    47041 gttcatcgta agcataagtt ttcttctgaa aagattttat ctgaccagtt aattgaaaaa
    47101 gcaagaacag gaaatatcac tattgaatat aatcataacc ttgatgaggt attaggtgat
    47161 gtcaatggag taacagggat tcgtttaaaa aataataata ataagataaa agatattgat
    47221 gtgcatggtg tatttattgc tattggtcat acacctaata cagctatttt taaaggtcat
    47281 ttagaaatga taaatgacta tattaaagtt caaagtggaa cacaaggtaa tgctacacaa
    47341 accagtatag aaggtgtatt tgcagcaggt gatgtgtcag attatgttta tcgtcaggct
    47401 attacttcag ctgggtctgg ttgtatgtca gcgttagatg ctgaacgatt tttaggcgaa
    47461 taaccttttt aaaggttata atctactctt ttatacctgt aaagagtgta aaggccacat
    47521 agctcagttg gtagagcaag ggactgaaaa tccctgtgtc cctagttcaa ttctaggtgt
    47581 ggccaccatg tttatttgac tatattaagt atttttttat taagactagt tagagaattc
    47641 tattttcgta aagtattaat tttggttgat cacgaaatta aagattattt ttttgttata
    47701 agtagattga aagtttaaca gtattagcaa ttagtattat attattaatt gttttatgat
    47761 ataatactgt tatgtcgccc ttaagaaata ctctccttaa gagataagtt ggcgacatac
    47821 ttctatcgtt agttataatt tcataatttc ataatttcat aattttaaac tgggttattc
    47881 agtaaaatta atttttctaa tggagtatat tcttatttgt aaggttcttc agaatcaatt
    47941 tttacaatga ctttgtttaa tcaatcataa aggttaataa tgttatttaa cagagttaag
    48001 ttacacaaaa tactatgtat attggattat tcttttgttg tatgttacgt gacttttaat
    48061 taattgtaat tcatgatttg ttagcaagaa tttgcatgac tgccatacgt attgcaatac
    48121 catcagtaac ttgttgcaat atgattgatt gattgccatc agctacaatt gagtcaattt
    48181 caacgccacg attaattgga cctggatgca taacaatagc atctgatttt gttagtgcta
    48241 gacgttttgg cgtgagtcca aaattattaa agtattcttg ttcattaggg atattagcct
    48301 caatcatacg ttctttttgt aatcttaata ctatcactac atcgcaatct ttaagtcctg
    48361 gttcaatatc atcaaaacaa ctgacttctg aacaaggttc tgaattgtat tgtaagattt
    48421 ttggagcaat aagacggata tcagtcgttc ctagagtttt aagtgcttga ataccagagt
    48481 gtgccacacg tgaatgaata atatcaccta caatagcaac tgataagttt tcaaatgttt
    48541 ttttgtgttg gcgaatactt agcatatcaa gtagtgcttg ggttgggtga gcgttaatac
    48601 cgtcacctgc gtttagaatg gagacacctt ctaggtattt tgctacatgg tgtggtaagc
    48661 cattttgttt gtggcgaatt acaaacatgt caatttgcat ggctttaagt gttcgcatgg
    48721 tatcaagtaa gtcttcattt tttttgagtg ctgagttagc aaggtcaacg ttaataacat
    48781 tggcactact tctcattgca gcaatttcaa atgtgttgcg tgttcgtgtt gatggttcaa
    48841 agaataaatt agcaatggac atatcatcaa gtgctttgga tttttttaag ttgccagagg
    48901 tatcaattaa gctatcagcc ttatcaagaa tatgagttaa atgttgtttg gaaagaccct
    48961 caagtcctaa tagatgaatt aatttaccag agtcgtttag ttgaatatgg ttactaatca
    49021 aatttttttt cattgagcca tgtttgtaat attaattgtg atgattgttt gtcaacatta
    49081 ccacgttgtg cattgtgatg atgatgattg tattttagaa gtttttttgc ttcatttgag
    49141 gataaatatt catcaataaa ttcgacttca atttggtaac gattttttaa tttttttccg
    49201 aatgatttgg caataaaagt cattatctgt tcttttcctt gtttgtcaaa tggtaatcca
    49261 acaataaata gcttaatatt atgactatta ataacttcat caagttcgac ccaattagtt
    49321 gaattgtctt tatgatgttt aattaccgca atacctgttg ctcgcatggt taaactattg
    49381 gctattgcaa caccagttct cttagtgcca atatcaaatc ctaaataagt attaatattc
    49441 actgtagttg ttgtaataat tgatagccaa catagccatc aatcggtaat ttatttgctt
    49501 tttggtatgc tcttgttgta caacgagtct tttgtcctga tataccatta ggttcacctg
    49561 tattaaagcc tagtttattt agcgtgtttt gaatatattt aatattatca ttactaagcg
    49621 aaggttcggt aatggatttc gcaaataatt gatttaagcc tattaaacga tcagataaat
    49681 agtacatata aaattgagcg attccacctg agaatagcat gaaaatttcg ataaattaaa
    49741 aatgctgggc cattatagtc cattggtaat atgagagatg cttgcatact tgagttggga
    49801 agattagcgc tatttatcat acgtatacct aagatttgcc atttatttac tatcttttaa
    49861 tactcaaatt cgttagttgg tagttaaaat ctttaggaat attaacctta cgtccccgac
    49921 gttctccttg ataccagcaa atatttttta gaaaatatac tgcactggca aagatatctt
    49981 cttgtgtatg ccataagtga atttttccat caagattagc atctatatca taagtagcta
    50041 cattagtggg tataaattgt atgctgccca tggcgcttgc ccaagatcct tgagtattca
    50101 aaggaagtct atcttcatcg atcagtttaa gtaaagtcaa taattcatga gtaaaaaatt
    50161 cacgtcggcg tttatcaaaa cttagtgttg caagtgagcg aattatatta atttttccaa
    50221 tatttttacc ataattagtt tccaaacccc aaagagctac aataatatga gtcggtatac
    50281 cgtatttttt ataattttct tgtaagtatt tttgatattt cttaagtttt attaaacctt
    50341 tatcaagcct attctgattc actcttgagt ttagataatg ccaaaaatta aggttaaatt
    50401 ttgtttggtt gcggtcatat tttaagactt taggatttgg tattaaatca ttaaaatagt
    50461 tattaatcgt agtttgtgaa atgcctaatt gaattgcttt gtagtgaact atcatttaag
    50521 aactgtgtaa aactatgtgt attagatgtg tcttgggtat catttgtata cgcaggtaat
    50581 gttaacaaca aactgaaaat aaattttaac atgtcaaaat tataatatct aaggtgttta
    50641 ttgtttttat ctttttattt ttaagttctt gtgttagtga aacagcacaa actattactg
    50701 gtacaactat gggtactgat tatagtatca aagttttgaa cacccaaatc tcaaagttaa
    50761 ttattgataa acgtcttaat gaaattgaga aaatattttc cacttgggat gaaacttccg
    50821 agctttcaaa attaaacaga gcgccagtta atcaatggat aaaggtatca gatgagttgt
    50881 tttttgtttt actccaagca aaaaaaatat ataagcaaac gcaaggtttt tttgatcctg
    50941 gtataggtcg tttaattgat gtttggggtt ttggtgttat taagacacag gtaaaaccta
    51001 ataaggaaaa gatagctaaa gcactagcaa tatcatccat tgagtatata catttaggcg
    51061 atttacgagt taaaaagctt aaagatgttt atattaattt gtctgctatt gttaagggtt
    51121 atagtgtaga tattgtggca aatatgctaa ttcagcaagg acttaaaaat tttatagtgg
    51181 aaattggtgg cgaggtaatg gctcaaggtc agtggacaat tggtattgaa aagccgaatc
    51241 atagcctgcc aattgctatt gaattgcaaa atttagctat tgccacttca ggagattatc
    51301 gtaattattt tgtttggcaa gaaaaaaaat atcaacatat tttaaatccc agtacaggat
    51361 tacctgctaa tactgactta agttctgtta gcgtgattca tgatagcgcg atgatagcag
    51421 atgcttatgc aactgctatg atggcaatgg gtagtcaaaa agctagaata ttagcacaac
    51481 aacttaactt atcagtagtg tttattttga atcagtggta tgattttgaa gtactacaat
    51541 ttcattaaaa tataaccttt attatagtat gtgtatttac actaagattt gtcagtattt
    51601 ttttgtttga ttaaaataaa aaaatattta gttatatgct atttgtagaa acgttaaagt
    51661 ttagaacttt agatgatttt tagttagtta tatttgttga atattaatat ttatgttgtt
    51721 aggatattta caacactcga ttgcattgta tgattctatg gaatctatta gatattggtt
    51781 aaatgatttt aatcaaaaaa ttattaatgg atatttcaca tgtctaagct atagataaga
    51841 cgaggtaaaa gaattacaga taatagttga taatgctaaa aaattataga aaatttagta
    51901 agtaaatggt tatcatctat acaataggat tatattatca atatatttat gtagtatgtt
    51961 atatggattc tatcaaagta tgaaatattt aatcaagtga tagttaagat ctaaaaaaca
    52021 ggatatgttt ttaaaataaa agaatttgta taacgtgttt aatttagttg atggtgtaag
    52081 taaaagtatt gctatgcatg tgtatatcat gtatttgatg tgcttgtata tggataaata
    52141 tctaatctta acgagttaga agaataagtt tgattgttta aaaattttag gtgaaatatt
    52201 aaaattattg aaaaattgaa acatctaaga gatttgtgat gagtgtttta ttcacaattt
    52261 ttgtgattgg tataggtgca actatcggtg ctagtatgcg ttattattta acccaattaa
    52321 tgaacgctac acttatatct gattttcctt atagcacttt ggctgttaat attttaggat
    52381 cgtttttagc gggtatattg gtagttatta tattagaaag agctacttta catgaggctt
    52441 atcggttgat gttgttaatt ggtttgactg ggtcgctaac aactatgtca actttatctt
    52501 gggaatctat tgaaatgatt agttttgggt attacggtca agcagggttg aacatcctac
    52561 ttaatgttgt tttatctcta cttgctaccg gcataggagt gatattgggc cgatattttt
    52621 tgatttctta gtaatgacta attttaatct tttgttcgat aacatcaaat aattcacctg
    52681 caatattaag attaaattgt ttgtctaatt cacgaataca ggttggactg gtgacgttaa
    52741 tttcagtaat ataatcacca attacgtcta gtccaacaaa tattaagcct ttagctttaa
    52801 gagtgggaga gatttgtttg cataaataat aatcatgttt acttaagggt tgtccaatgc
    52861 caattgcacc tgctgctaaa ttgcctttaa agtttccttt tgcgggaata cgagcaagtg
    52921 cataatcaac cggcttacca ttaattaata aaatacgttt atcaccttta gtaatatcag
    52981 gtaaaaattc ttgtaccatg attggttttt taccattatt tgttaggcgt tttagtattg
    53041 catctatttt tatatcgttt gttttaaatt taaaaatatc atgccctccc atgccgtcaa
    53101 gtggtttaat aatagcggta ttttgtattt tgataaaggt tttgatttgc atttgattgc
    53161 tactaattag tgtttttggt atacaatgcg ggaaatttag ggcaaatagt ttttcattgg
    53221 catctcgtaa agattgtggt ttattaatga ttaatgtatt tttgttttca gattgttcta
    53281 ataaataagt tgcgtaaata tagttcatat tgaatggagg gtctttacgc attagaataa
    53341 cgttaaattc actaagtatc attattgtat ttgtttcttt cttaaaccaa tgattaagat
    53401 tatcatgaac cgtagttttt gcacaattag caaatactga tccatcttga gcaaatagat
    53461 cacaagtatt aaaagtgtaa atctcccagc ctcgttttga tgcctctagc atcatagcca
    53521 aggaagagtc cttttttgga ttaatattgt tgatattatc cattaataca gcaattttta
    53581 tttttttcat aattcttagt attatagtgt ataattcaca ccctttagtg cggggtggag
    53641 cagtttggta gctcgtcggg ctcataaccc gaaggtcata ggttcaaatc ctgtccccgc
    53701 taccagttaa gtactttttt attaactagg ttaataaaaa agttgattaa gaccccattt
    53761 ataggggttt tttgttatgc attgaaagat aaagttaata gaaatatatg gcaagagtaa
    53821 ctgacaaaat tacccattta attaagcctg ttattgaagg tatgggttat gaattgttgg
    53881 gtattgagta tgtcgctagt ggtaaatata gcatcttgag aatttttatt gatacaaata
    53941 aaagtattag tgttaatgat tgtgaaatag tttctcgtca attgagtagt atttttgata
    54001 tagaagaacc gattagtggt caatacaatt tggaggtttc atctcctggt attgagcgcc
    54061 cattatttca taaggggcat tatcagtgtt ttttaggttt taatgttaag ttacatatgt
    54121 ttaggccgat tagtggtcaa agcaattttt ttggtgttat tggtagtgtt agtgagatta
    54181 ataatacgat tgagctggtt ggtgaattag gagcaattat tttggatatt gatttgatta
    54241 aaaaagcaaa tttagtggtt gatttttaag ctcaattagg taacttgggt aatgtaggag
    54301 agtaaagaaa tggacggtaa agaattattt ttaatggttg aggcgatttc aaatgagaaa
    54361 aatatctcta aagaagaggt gcttgagtcg ttagaaaaag cattagctat tgcgacaaaa
    54421 aaacgaaata atattgatgc atatgttgaa attaatagac aaacaggcga gttcttaacc
    54481 tttagacaat ggatggttgt ggcagatggt gagttgtttg ttgatgatga tggcactgag
    54541 tttgatttag aattacacat ttatgaaaaa gacacggatg gtttagtggt tgatgattat
    54601 atgcgtaagc caattgaaac acaagagttt ggccgtattg cggcacaaat tgttaagcaa
    54661 gtaattattc aaaaggttcg tgaagcagaa agagaagtaa ttgttaatga ttattcctca
    54721 cgaattggcg aagttattat ggttacggtt aaacgtgttg atagaggaaa tatttatgtt
    54781 gatatgggtg gtgttgatgg catgattcct aaatttgact tgattcctaa tgagtcggta
    54841 cgtaaaaatg accgtttaag agcttatatt aaagaggtaa agtcttctat tcgtggtgta
    54901 caaatttttc tatcacgtag cgtgtctgaa atgatgattg agctattcaa aatggaagtg
    54961 ccagaaattt ctgcaggtgt gattgagatt atgggtggta gtagagaccc aggtttgcgt
    55021 tcaaaactag cagttagagc taaagataaa cgtatagatc caattgggtc ttgtattggc
    55081 atgcgtggtg cgcgtgttca ggcggtatcg aatgagctaa atgctgagcg tgttgatatt
    55141 attctttggg atgaagatcc tgcacaattt gttattaatg caatggcacc tgctgaagtg
    55201 agttcaatta ttgttgatga aaataaacat tcaatggata ttgcagttga ggatgagcag
    55261 ctagcattag ctattggtcg tggcggccaa aatattaagc ttgcttctcg tttgactggt
    55321 tggaaattaa atgtgatgtc aacaattcaa gctgacgaag agcaagtaca ggagatgcaa
    55381 aaaattagcg ataagcttgc tgatcaatta ggtgttgatt ctgaagtggc gggtgtattg
    55441 attgaagaag ggtttgatag tgtggatgag ttagttgatg cagatacgca agttttagga
    55501 aatatagaag aatttgatgc atcaatggtt gaagaactcc aagaacgtgc atcagatgca
    55561 caattagtac aagccttggg agatgcagaa gcttctgaaa tacttatgag tgttgaaggt
    55621 gttaatgagg atttggcaag tgtattaatt gaagtagaca tttttactgt tgatgattta
    55681 gctgaattgt ctattgatga attactagat atccaagata tggatattga aatagcatca
    55741 agtattatca tgaccgcaag agaaaatgaa ggatggtttg attaattgat catgagaatt
    55801 tattttaagt taataattat aaaaaatagg caagtattat ggcacacacg gttcaaacac
    55861 tctctaaact actgaaaaag acgcctgatg aggtagttac aattctagcg aatgctggtg
    55921 ttgatggtaa aaattcagat tctgtcattt cagcagaaga aagaaaaata ttaatgagta
    55981 gtctttcaaa gcgtccaatt agaagatcta gcatgtctgt ttttcgtaaa gcaggtacta
    56041 agtccaatgc cgtttcagtg agtgacgtta aagtaaaagt taggtcaaaa cgcttgacac
    56101 agccaattac aatgattgat gaacagtcta aagttgttgc taacgaaatg gctagagctg
    56161 ctctagctgc tttggatgct ggtcgtaatg cagatgaaat attattggcc caagatgcta
    56221 ggcgtttgga aatggtgcgt ttgcaaaaag cccaagtaga agtggtagag atccagaaag
    56281 aaacggttaa aaaagtgcaa gagaaagaag ctgaaaagaa agttgaaaaa ctaaaaacgg
    56341 cagacaagcc taaagaaggt aataaaccta aacgcttacg taatacttct agcgataata
    56401 atactcgcaa gcaacttcat gtcgctagac ataatcccaa tcgaagatta aagaaaaaag
    56461 atagaacaca tttgtcacaa aaaatacaag cagaacaagc gcaacatgct ttccaaaaac
    56521 ctattgaaaa agtaattcat gaagttgcta ttgttgggaa tatcaaggta actgaacttg
    56581 cacaaaagat ggctactaaa gctggtgaag tgcttaaagt gttaatgggt atgggtgtta
    56641 tggtgacatt gaatgatgta attgaccaag atactgcctt gttagttgta gaagaaatgg
    56701 gccataaagg tattattagt gttgaagaaa ccattgaaga tgtattaatt gaacagttaa
    56761 aatataatga gcatgaaagt gctagaccac ctattgtaac tattatgggt catgttgatc
    56821 atggtaagac ctcacttctc gattacatcc gtcaagccaa agtagcgcat ggtgaagttg
    56881 gcggtattac gcaacatatt ggcgcttatc aagttcagtc aaatggtaat attattactt
    56941 ttattgacac accaggacat gcggcgtttt caaaaatgcg ttttcggggt gctaatgtga
    57001 ccgatattgt tattttagtg gtggctgctg atgatggcgt gatgccacag acgattgagt
    57061 ctattaaaca tacacaaatt gttggcgtgc ctatgattgt tgcaattaat aagatagata
    57121 aagaagggac ggatgttgat aaaattaagc aagtcctttc aacgtatgat gtaatctctg
    57181 aagattgggg tggtgatgtg ataatggttc ctgtatcagc tcatactggc gaaggtgtgg
    57241 atgctttatt agatgctatt tcactcactg ccgagatttt agaattctcg gcagtgagtg
    57301 aaggtccagc gcatggcact gtactagaag cacgtcttga aaaaggtcgt ggtaaggtga
    57361 ccactatttt agtacaatca ggtacattga ataaaggaga tattatgatt gctggattcg
    57421 aatatggcaa agttaagcaa attgtggatg ataaaggtaa aatacttaaa ttagctatgc
    57481 catcaatgcc tgtagaggtg ttaggtttgt ctggtgtgcc taactccggt gatgaagtaa
    57541 tagttgtagg tagtgagaga aaggctcgtg aggtggctga ttttagaaaa tctaaagatc
    57601 gtgaagtgca gttgcagaaa cagcaagcat cgaaaatgga aaatttttta atgaaaatgg
    57661 aaaaaggtga tatttcaacc gttaatgtat tacttaaagc ggatgttaga ggttcagcgc
    57721 aagcattaat tgaagcctta gaggaattat caacggatga ggttagagtg aaagtagtgt
    57781 caagtggtgt tggcggtatt aacaatactg atattacatt agcagcaact tctagtgctt
    57841 tagtacttgg ttttaatgtt cgtgctgatg ctgttgcacg taaaacagct gacaatgaag
    57901 gtgttcgtgt tgaatattac tcaattatat ataacttaat taatgatgtt aaagctatta
    57961 tgagtggttt actcagccca gaattgagtg aaaatattat tggtattgcc tctgttaaaa
    58021 atatatttaa atctcaaaaa atgggtgata ttgctgggtg tatggtggat gaaggtatgg
    58081 ttaaacgtga tagcctaatt cgagtattac gtgatagtgt agttatcttt gatggtaaac
    58141 tggagtcatt aagacgtttt aaagatgatg tgaatgaagt taaatcaggt actgaatgtg
    58201 gtattggtgt acttaattat acagatgtac aaccaggtga tcaaatagaa atctttgaac
    58261 gtgttgaaag ggcgcgtata ctttaaaatt tttgatataa gtgttagaac aagaacaagc
    58321 ctcttataga gttgaaagaa ttaacgaatt gattcgtcgt gagttgacgt tattgttaag
    58381 aacctctatt aaagatccaa ggttacgtga catgataatt actgatgtac tgataagtcg
    58441 tgatttaagt agtgctaagg ttttttatac agttattaaa gaagacaaaa aaatgattga
    58501 accactactt gataaagcta gtggtttttt tcgtatacat ttatctaaaa cgattgatct
    58561 tcgtcacaca cctgtactta ggtttatctt tgactctgcg cctaatacag gcgcaagaat
    58621 tgaacaacta ctatctaaat tgtaaaagac tattatatta atattacatg ttaaggcgta
    58681 atccaaaagg tagaagtatt aatggtattg ttttattaga taaagatatt gggttaagtt
    58741 ctaacgctgc cttacaaaaa gtaaaacgac ttttttttgc taaaaaggcc ggacatacag
    58801 gtgcactaga cttttcggct agtggtattt tgccaatctg tttaggacaa gctactaaaa
    58861 ttgcacagtt tttactagag gacgataaac gttattttgt gcgtggtaaa ttggggcaaa
    58921 taagtgatac tggtgattgc gaaggcagta ttatcaaaac ccaacctttt gaacatttaa
    58981 gtgatagtga aattgctaag gtaactgcaa gttttaaagg taatattttt cagattcctc
    59041 ctatgtactc agcacttaaa agagatggac aaccattata taagcttgct agaaaaggca
    59101 tagaagtaga aagagagtct cgtctagtta ccatttataa aattatctat cttgggtata
    59161 aaaacggcat actttcactt gaagtaacat gttctaaagg tacttatatt cgtactttga
    59221 tagaagatat tggggaaaaa ttgagttgtg gcgctcatgt tattgagctt agacgtacag
    59281 gttttgcaca tattgatatc aggcaaacct tgacattttc tgaacttgaa attttggcat
    59341 ctaatgatta tcaagcactg gatgagaaaa tacttgccag tgaagatatg ttattaggcc
    59401 ttgaagatgt ttatctgagt aaggttcaaa gtttggatat aaaatttggt agagaaattc
    59461 agacagataa gcaaggatta cttaaagtga agttatttaa tgagaaaaaa caatttttgg
    59521 gtattggaca atgtcaagga aatggaataa ttttaccaaa aaaattattt atatgagcaa
    59581 aaaaagatgc actagttgta gttggtggtt tctttaataa caaattaata tactctatca
    59641 agcacgataa aaatttgcac aaaagtgttt ataattatga aaaaactttt aatattgtgc
    59701 tattttaaat ggactattat tagtattatc ataaattttg taacaatgtt gtttaatgat
    59761 tatagtatac aaattatagc acaaaaaatt ttaagtaatt tattatggag tgtttatgaa
    59821 ggttttagtt attgggggtg ggggtcgtga acacgctttg gcttggcagt gtagtaaatt
    59881 tgatacagta agtcacgtgt ttgttgctcc tggtaatgct ggtacacagt tagaaactaa
    59941 attgactaat attaatatcc ttacggatga tatagtaggt ttaattaatt ttgtaaaaac
    60001 caatcaagta gatttaacca ttgttggccc tgaagctcca ttggtaatag gtatagttga
    60061 tcgttttcaa tacgaaggat tagcaatttt tgggccaact aaggctgcct ctcaacttga
    60121 gtggtctaaa gtattttgta agtatttctt ggagcgtcat aatattccta cagcgcatta
    60181 tggtgtattt accgaagtag aacttgctat cgaatatgtt aagaatcaag gtacacctat
    60241 tgtaattaag gctgatggtt tagcttcggg aaagggtgtg attattgctt atacacaatt
    60301 tgaagctaaa aatgttatta ttgatatgct acaaggtaat tgtttcggta aggcaggttt
    60361 atgtgtggtg attgaggagt ttttgagtgg tgaagaagca agttttattg tgatgtgtga
    60421 tggtaaaaat attttgccaa tggcaacttc acaagatcat aaagctcgtg ataatgatga
    60481 taaaggtcca aatactggtg gtatgggtgc ttattctcca acgcctatta ttactgatga
    60541 aatttttcaa tcagtaatgg ataccattat ttatccaact gttaatgcaa tggcagaaga
    60601 aggaaatatt tacacaggat tcttatatgt agggttaatg attgaccaag ataataattt
    60661 taaagtatta gagtataact gtcgctttgg tgatcctgaa acccagccga ttatgatgcg
    60721 cctcaagtct aatttagcag atttatgttt attagcaaca caacaaagct tagatcaagc
    60781 gaatattaag tgggatgagc gtatttgttt aggtgtagtt ttagctgcaa aaggctatcc
    60841 aaatacttat aatactaatg aattaattat attgccagaa gatagtcaag ataccaaagt
    60901 ttttcacgca ggaacaaaac tagaaaatgg taaagtgttt tctagtggag ggcgtgtttt
    60961 atgtgtaact gctttgggtg aaaatattta tagtgcacaa acgaaggctt ataagttggt
    61021 aaaaagaatc aattgggatg gttcttatta tcgagatgat attggattta aagctattaa
    61081 aagactatat tctatttaag tattattcta atacttaaat ttatcttttc tcttaataga
    61141 aaaatttaat tttttaaaaa ggttatcttt ttgtgataag ttgattataa gttatagtaa
    61201 gtttagtttt cacttgaaaa tccgttgtat cgcaataata gaggtatgct taacactatt
    61261 taatcaacta ttagaattta aacaatagtg ttgaaatgat tagctgttat acactaatta
    61321 ccaatcatgg cagtagggtg aagcaggtgt aattaataaa attagcattt ttaggttata
    61381 ctatgttgtc gataaagaaa gctacagttt aaaatttaaa tacttaattt aatcaagtat
    61441 tagtggatag taatagttgt actgattttg actattgaaa gatagtgtaa ttaagcttga
    61501 aatcagtagt atcgattttt tgtcaaagta ataacatgat aaataaataa ttgaattaga
    61561 taagttatga gatttgctaa atataagagt tgtgttgcta aattgaaatg cgtatcatag
    61621 ctttaacaaa taataaacac tgttaatcat ttactctagt gaacatttct atttaatacc
    61681 cttatttgat gttttagatt agcttttttt acttcaagtt tagctttttg ttcattttca
    61741 agcgatttaa gtctatcacg ttctatttca gctttggggc gagtttttat gtaatcaaat
    61801 aatttgataa ccttgcaaac acctctggct ttagcggcag ttttggcggc catgtctgcc
    61861 tctcgtttag ttacggcacc cataagataa actacttgat tttcagtcat cacctgaacg
    61921 tgggttggat gaaatacttc ttgattctga aataggaatt caacttgtat agtgatggtt
    61981 gaatctttag ctctactaag tagtccattt gaagggccta atttaatttc attaaatact
    62041 tgtgaaattt ttggtacttg aagttgtgct tgtttactta cataaatacg tatcttaggt
    62101 gttgttactt ctccagtaat gagtactgtt ttgttataaa ccatgaaatt aagatgtgca
    62161 ttatttaata ttacatcttt gttagaccag gtaaataacc ttagagcaat ggttttatca
    62221 tctaatactt ctccagcact acgcctgtca ttacttactg agataattga gctaacagtt
    62281 gaaacacctt gaatagctga tacacaagct gttagaagta agaagtttgc cattagaagt
    62341 gttaatagaa tgaatttttt catgatgtta tgtctttact ttacacacta tatttaaaat
    62401 attttaaatc agatttaagt ctaatgagat caaatttgta cagataattt tgatattttt
    62461 tatttttgaa taattattta tatcatagaa ctgaaggaat tgttagcacg atatatattt
    62521 tcaataaaaa ctagtattta gttgatttta tcaagcataa taatatttaa ttttactcaa
    62581 tcatgattta atattttttt aatgagttta atatgttatt tgaataaata tgtcaataaa
    62641 atttctttta tctgatagtt aatttttttg taaaactgaa tatgaatgga acgctttata
    62701 ttatcgctac accaattgga aatttaaatg atatcacttt tagagctatt gaaacgttaa
    62761 aaacagttga tattattcta gcagaggata tatgtcactc taaacgctta cttaatcatt
    62821 atgatattac aacatccatg tatacttttc atgaacataa tgaaagatgt aaaacccctg
    62881 atataataaa taaattatta aaaggaaagc attttgcatt gattagtgac gcaggaacgc
    62941 cacttattag cgacccaggt catgtattag tgatagaggc gaaaaaagta ggtattaacg
    63001 tatcgcctat ccctggttct aatgcaatga ttagtgcaat tagtgtatca ggaattgcta
    63061 gtaacaagtt cagttttttt ggttttttgc ctagtaaaca atcggcgcgt cttaaggtga
    63121 ttcaatccat tgtaaatatc aatgaaatgg ctatttttta tgaatcacct aatcgtattc
    63181 tttcctgtgc gcaagattta caaacagtat tgggtaatga acgtattgtt tgctttgcca
    63241 aagaactgac taagttgttt gagactatta agacaaatac attgcctcag ttgattgatt
    63301 atttacaagc agataataca caccaaaaag gtgaatttgt gattcttatt tctgcagcaa
    63361 agaaaaacaa tgaagtctca ggagaagaaa tgttgaataa agtattacca attttgctca
    63421 ttgagatggg tgcggcaaaa gcagctaggc ttgtagctaa aatgactggt tttgataaaa
    63481 gatactgcta tcaaagagct attgagttat aagtatcttt tataaacctt tatacaaagt
    63541 atgcttactt tgataacaac accagttaaa aactattacc cataatttta tttttaaaaa
    63601 atataatttg cattatagat gaggaataag atagggttat agtaagttgt gctattttat
    63661 ggtgttgtat gggtaatata atggttgttt atattgacga ataagacatt aataatatta
    63721 caatccaata aatggtaata ttgttaagag attataagtt aattagtttt ttatacaact
    63781 gattagtttt atgggttaaa tcagtaattt ctaggttatt ttcaatgata tcagtaggta
    63841 atttttcacg caattttaag cgtaatgcat gactaaattg tgtagaaacc atattttttg
    63901 cttcatttgt atcaatatta tcacgattaa tcaatctttt caattgttgt tctttattgc
    63961 agttaataat aattgctcta ttaaacaaat gagtaagatt cttctcagcc aatagtggta
    64021 cttcaaccac cactaatttg gcttttagtt ttctaatttc attttccata cgtattaata
    64081 ttcttggatg tagtattgct tcaatcaatt tttgattaga ttttttttct aataaaattt
    64141 ttcttaaaat actacggtta aggcttgtat tagtattaag aatatcatca ccaaagtgtt
    64201 tgattaattc tttaagttca atcgtgttag gtttaacaat tttttgtgca agcttatcaa
    64261 ggcttataat atctaaacct aaattactta agatttgact tacttttgat ttaccacaag
    64321 caattccacc tgttaatgct attttaatga tcgacatatt aaattgattt tatcaatatt
    64381 acatattatc tattgacatt tatactaaat ctttcgataa tgcttctttt tatagttatg
    64441 tggttatgta gctcagctgg ttagagcaca gcattcataa tgctggggtc ggtggttcaa
    64501 gtccacctat aaccaccata ttatataagg ctttcagact tttatatctg tttataaata
    64561 actctaggat aacacaatat caatatttaa atgttattta aagcagttta gaattgtttt
    64621 taaggtgtat gttaaaatct atttaatcct ttattattta aaagactaat aaagccactt
    64681 cgtgatattt tagtcagata aatttttcca ttgggttttt tggataaata cgccataata
    64741 tgttttttct aagtcagcat caccaaaatc tgaaaaggtt actatctttt aatttttcaa
    64801 tagtttagag tccatataaa attcgatgaa aagaggttgt ttgtacgttt taacttcaca
    64861 aaataattga ttattatctg tttttctcct tgtgtctagt tacttttttc tgtagaaatc
    64921 atgtgtgtga gagatactct tcagattgta tagcagaatg ctaaaattca acaatctatt
    64981 ttatcaggcg ttttgacatc tacaatgtgt ttttcactaa ccttatcatg atgaattata
    65041 ttttactatt cttattgatt tttatagtta cgatgccatt cagttttatt cggtagtttc
    65101 tttttgttag tccgactaca ttttgatttt accatattta gtagttagtt cagagctgta
    65161 actatagtat atttattggg ttctatttgt aagtctatta cttgcaccaa cttaatttct
    65221 taccaccgta ataattataa gctaaaccat tatcaagtag ctcctgttct aaactaaccc
    65281 catcaaccat tacattggca ataactctga agtacttacc tctttgtaaa ttagtcaact
    65341 taatttcttt agcattgttt agcttgcctc ttacaaaatc tcttgccttg atggctatat
    65401 tcttttcata ctggcacttt cctcgtattt ctggagtgtc tatcccattt attctaatag
    65461 gtatattcct acctacgata ggcggtaata agtctatatt tactctaaag gtatcaccat
    65521 cataaatact aatgactttt gatactatta ctgtaccgta ttggggtttt gattgtactt
    65581 gaaaaacaag agttgctata ataatagata aaaatagttt cataaattta atgattagag
    65641 tctatttcta atatgcatct ttaactactt gatacttagg gatgcttgta aatattcata
    65701 taattaatac aagtattatg aatattagtc ggtgtttttc atttcatttg ttgcttttat
    65761 ttaaatacct aataactcca atcactttat acaactatta ttaatcctta acaaaatttg
    65821 tataaatttt attctgtctc tgcttgctta gttcaaccat acaagaagga tgtgtgatga
    65881 atctcattgt acaagtatat agtattacac tctaaataca ggtatccaat gactttaaaa
    65941 acaacactag aaaaaatgac aatattttat tcttttcttt catattttat tcttttcttt
    66001 catattttat tcctatggtt tgctcttagt gctagttgag taaggtattg aatatcctga
    66061 gttgtgataa ttgtatccat cagttgaacg attattatga ctactaaatt agttctgcta
    66121 ttctgtgtta aattagaagt attgcggtta gtagtaattt cataactgat tttaactatt
    66181 cgaatgatta tatgatatta ttatttaatg ttaaattaga tccgattaat tgatcttgcc
    66241 agactatctt tttatgagta ataataatct aaagcaatat ccatactcta gtggttatta
    66301 aagttagtat ttagattaag caatgtatct catgaatcgt aaaagtaaaa agagagttga
    66361 tctttaaaat aaagattttt tagggtttaa ccctaaaata ttactacaag gaatataaga
    66421 ttcattaatt aaaagttgct atcatgatac tcatttaact taatacttat ataaatctat
    66481 cctatactct attctttctt taggaattct cgttcagata acttagtatc gagtatatgt
    66541 tgtttcatat gcgactcatc atcatcatca gtccagtttt tgtagaattt atataaacca
    66601 gaagctttaa ttatttggtt aataatgtaa caatcctcca tccaggaatt aattctatcc
    66661 atctcatatt tatatttaat aatagtatcc acaatattct ttggttcttt ttaaccttta
    66721 cttttgtaac tctaaatatc cttcaatagt tcaaataatt cctgataatt cttgtttaaa
    66781 tttattttgt agcttcttat attggtctta atctttaatt attatcttaa aaggaattag
    66841 aacttaagaa tctttagata ccatatccat atccatatcc aggtgctggc ttgtgattat
    66901 cattaattaa aaccttaaac tctagtctaa agaatctagt aataatcaga tcctgattgg
    66961 tgagaagttt tagttaggat ttattaaact tagagccttc tttagtttta gtagtaacaa
    67021 taaaccttgc aatctttaaa cgtactatgt tgttattaat aattccctta gttctatcaa
    67081 ttaaaatgct cactgttgtt tgtttatcta ttgaaaggta tttataaata cacttttcca
    67141 ttagcacttt taaccataaa agaaaaataa cttccgttct ttaatgtctt tatttagtga
    67201 ataactaaca attatttgaa gatagttaat catattttga tcgttattaa tagcctaatt
    67261 taggaacgat atttataacg agaactttgt tttaggacta tagacaacta gtgcttgttt
    67321 agtaataaac ttagctttgg agttttttaa gactttctac ccttattagc cacacttaat
    67381 aagtacgtgt ctgtgtctag ttcttattct taatggaatc tatagttcat tttttgctaa
    67441 atgaatgatt gactagatag cttgtctaga ttcagatcga gctgtatatt tgctcatctt
    67501 acgttttcta ttataatcct taatcctgat acttagtcat atcgtaataa tgcatcctgt
    67561 tttgttagtt tatagatatg tccatcatca ttaaaatgcc atctatacca attcaaatac
    67621 atccatttat catgctgatg tgtaaatcct ttgcactatc tatttcagtt aagtgctctg
    67681 aaccttctcc ttatagatat gaatatgtac tgttaaggta cttaattgtg ctgcatttag
    67741 aagtatttgt aacttggcga ttagttttat acttacctag ttaaatctaa gggtattcca
    67801 accagcacta tctttcttga cactattaag tcggtactct aaaatacatc gagtctagat
    67861 ggttagttag ttaatatcat aagcagctct tgaggaagct cggtaatctt ttatctttaa
    67921 actcgtaagg gtatagaacc tgatgcgatt atatattcgc tatttagcat ggatatcgat
    67981 acctagtttt gtctactact ttagagggta actaaagtag taatgcaaat catctgtagg
    68041 tgttatgtat ctaccttagt atcaaggttc accacatttt tttaatagtt gttatgcttc
    68101 cagcatcgtt cttcacattc atatcaacga caactaagtt ggttatctta tcagttggta
    68161 accatcggca ttagagttct tatctaacca gtaattaatt gatgtatgca tctttattag
    68221 ctgttaacat attctttcaa atacaataga actgtccgtt tctgatttaa gcctattcaa
    68281 catgtccaat aaacagtata ttaatgatag cgtatggttt catagttttt attattgtaa
    68341 gtagtgaaat tttatctttg taattaatat taccccactt taggtttgta gcctctcttc
    68401 tatgtaaatc agtaaataca agcaggtctc taatagtatc ttcttgattt agttttttta
    68461 tttggtagct cttgtacaat cttgtactat ttctttaaat tatatgactt tattatcgct
    68521 tttctacgtt tttctttatt ctagacttta atatggctaa gctttttagt tgatttatta
    68581 attattatag gtttgactat tacttcatac ttaccttatg tacaattaaa tgaagttcta
    68641 agcagtttct atagaagtgt tggcttttgt tgtagatttt tgagtcatgt ctctgtattt
    68701 cttatccaca tcatcacgag taatacttaa tatttcttat ctttccaatc agatagatag
    68761 ttattaataa tataaggtgc aatgacttgt aatataatta tccagcacct gtgaaagggc
    68821 gataatttta ataacttcac tttttacttt tttggattaa ttacatcact gatagtgttt
    68881 aaatattatt tatattttta ctttttgctt tctataaccc tttaaatgta attacgtctt
    68941 cgtacaagaa ttgatttgat tctattatta gtaatttaga ggattagtcc attaatttca
    69001 gatacgggct tgcagagaat taattatttt atttgtgaag cttatcgact tactcatatc
    69061 ttttatttag ttagagctac agaatgtggt tatttgagag tgagtaagta caaatgtaat
    69121 ggaatccata atatgatact attttacaag tattttatga cattgtatgt atagatttag
    69181 ttggttcaac tccactcata accaccataa taatgtcgtg attgagatta tgttttaatg
    69241 tgtatctttt atttttaatc taacgtagaa agattagcgt cataatttaa ttaatttctc
    69301 ccatgattat gattattctt ttgttataag aaatcatttt tggagtgtct tgattaaaga
    69361 gtagtttttt acgtataatc atttagtatt ttgttcaagg aattttacta tgccatcacg
    69421 cagagattta gcaaatgcca ttcgtgtttt aagtatggac gcagttcaaa gggcaaactc
    69481 aggtcatcca ggtgcgccaa tgggtatggc agatattgca caggtacttt ggaatgatca
    69541 tttaaagtat aacccaatga atgctaagtg gactaatcgt gaccgttttg tgttatcaaa
    69601 tggacatggt tcaatgctta tttactcatt attacatttg tcaggttacg accttaatat
    69661 ggatgatatt aaagattttc gtcaattaca cgctagaact gcagggcatc ctgaatatgg
    69721 ttatgtagat ggtattgaaa caacaacagg tccattagga caaggtatta ctaatgcagt
    69781 gggtatggca attgctgagc gaacattagg tgcacaattt aacaagttgg gtcataatat
    69841 tgttgatcat aacacatatg tatttatggg tgatggttgt ttaatggaag gtttatctca
    69901 cgaatcttgt gctatggcag gtacattagg acttggcaaa ttaattgttt tttgggatga
    69961 taatgatatt tctattgatg gtcatatttc tgattggatg gaaaaagatg tggcaagtcg
    70021 ttttgagtct tatggttggc atgttgttcg tgatgttaat ggtcatgatc ctgatgcaat
    70081 taattctgca attaatgcag ctaaggatga gattactaag ccctcattta tttgtacacg
    70141 cacaactatt ggttttggtt cgcctaattt atgtggtact cacaattgtc atggttcgcc
    70201 acttggtaat gaggagattg cagcaactcg taaagagttg ggttgggatt ttgctccatt
    70261 tgaaattcct gtagatattt atgaaggatg ggatcataaa aaaaaaggca ttgctgatga
    70321 attagcttgg aatattaaat ttgcagctta taaagcggag ttttcggcag atgctactga
    70381 gtttgagcgt cgtatgtcgg gtgacttgcc tgctaatttt gaagttgaga tggatcaatt
    70441 tattgctaaa acacaagatg aaatgccaag tattgcttct cgtcaggcct ctcaacgtac
    70501 tattgaagct atgggtccat tattgccaga aatgtttggc ggttctgctg atttaactgg
    70561 ttctaattta accaattggt caggaactgt taaagtgaat gcagaaaatg caaatggtaa
    70621 ttatctttca tggggtgtac gtgaatttgg tatggcacat atgatgaatg gtatagtgct
    70681 tcatggtggt tttaaggttt atggcgcaac tttctttatg tttatggaat ttatgcgtaa
    70741 tgcattacgt atgtcagcac ttatgaaaat tggtacaatt tatgtttata cccatgattc
    70801 tattggttta ggagaagatg gacctacgca tcagccagtt gagcagttag caactatgcg
    70861 tatgattcct aatttccagt cttggagagg atgtgatgca gttgaatcag cagtttcctg
    70921 gaagatggcg atgcttagaa gcgatgcacc aacaggattg gtattttcac gtcaaacttt
    70981 gacagcaatg gagcgaactt ctgaacaagt agaaaatatt gaaaaaggag gttatgttct
    71041 taaagattgt gaaggtttgg ctgatattat ttttattgca actggttctg aagtgaactt
    71101 agcaattgaa gcagtagcgg taataaatgc taaggttcgt gtagtttcaa tgccttgtac
    71161 aaatgcttat gatgatcaag atcaagctta taaagattca gttttaacgc caggtattaa
    71221 gcgccttgcg attgaggcag gtgttgctga tggatggtat aaatacgtag gtttagatgg
    71281 tggcgtggtt tgtatgacaa cttttggtga gtctgcgccg gcagatcaat tatttaaagc
    71341 atttggcttt acaatagata atgtcattgc aaaagcaaaa gccattatcg gttagataat
    71401 acatttaaat atggtaaaaa tgactgataa tttttgaggg tttttaatga aatttatatc
    71461 taaatggtat aatttaatga agtaaaaaag gagtaataaa atggcaataa aaataggtat
    71521 taatggtttt ggtcgtattg gtcgcatggt atttcgtgca attgcaaaag attttccaga
    71581 attagaggta gttggtatta acgatttatt agagaataat tatttagcat atatgcttaa
    71641 atatgataca gctcatggtc gttttgatga taatattaca gttgataata ataacttatt
    71701 tattaatggt aaaaaaattc gcttgtcagc tgcacgcgat cctgctaacc ttttatgggg
    71761 cgatattgat gtagatgtag caattgactg tactggtttt ttcttaacta aagaatcttg
    71821 tcaatcgcat attgatgcag gtgcaaaaaa agtggttcaa tcagccccat ctaaagatga
    71881 tacaccaatg tttgtttatg gcgtaaatca tactaaatat tcaggtcaag ctattatttc
    71941 agcggcgtct tgtactacaa attgtcttgc accaatagct aaagtgatta atgataattg
    72001 gggcctaaag cggggtttaa tgacaacaat tcatgcatca actgcaacac agaaaacagt
    72061 tgatagtcct tcgatgaaag attggagagg cggtcgttct gtatttgaga atatcattcc
    72121 ttcatcaaca ggagctgcta aagcagtagg tgttgtatta ccagaactta atggtaagtt
    72181 aacaggtatg gcatttcgta ttccatcagt tgatgtttca gttgttgatt taacttgtga
    72241 gttaaacaaa agtgcaactt atgaacaaat ttttgacgct atgaaagagg cttcacaagg
    72301 atcaatgaag ggtacgttgg cctatactaa agatgcagtt gtttcaagtg attttcgtgg
    72361 ttttagcgct tcttcaattt ttgattatga tgcaggtatt gctttggatg atacgtttgt
    72421 taaagttgta tcttggtatg ataatgagta tggttatacc tgtaatatgc ttcgcttagt
    72481 tgagtgtgtt gcttaattta ttaaagatac gtctcatatt gcttactagt tgtgttttta
    72541 ttttatattt gtatatgaaa aattcacaac taaattttgg ttagtttttt ggaaaattaa
    72601 aacaagttat tataaacaat cagtttaata ttttagatat atttgatatt aaacatatac
    72661 tagaaataaa gactaaaaat tagcagagga gtatagtgta tttaaaattt gtaaactaaa
    72721 agttgcaaaa gatattactg aaaaggatat caatttagtt acaatgttgt tgtgttgaat
    72781 ttcggtatat acttagaata atgttaccaa agttgggtta gtattactat ctaaataaat
    72841 tattaaacta tcgaatgcca atgtattatt gttgttagtt gagcttgttg aaaaaatcct
    72901 gattaaaatt gttgatcaga ctgttgaata taggagaatt attatgtcag ttattaattt
    72961 atcagattta gatttaaact caaaacgagt gttaattcgt caagatctta atgtaccgat
    73021 ttccaatggt gttgttacca gtgataagcg tatcaaagct tcgttaccaa ctattaaaat
    73081 ggctttgaat caaggtgcta aagtgatgtt aatgtcacat cgtggtcgtc caattgaagg
    73141 cgacccaagt gatggattta gtctgcagcc tgttgcagat cgtttaagcg agttattaaa
    73201 cactacagta cgtttagaaa aagattggtt ggatggtgtt gagatgaaca acggtaaggt
    73261 agtgctttgt gaaaatgttc gctttaacgt cggtgaaatg gttaatgatg atgagttatc
    73321 taagcgtatg gcggctattt gtgatatttt cgtgatggat gcatttggta ctgctcatcg
    73381 cgctcaggcg tctacttatg gcgttgctaa atatgcacct attgcttgtt ctggtccatt
    73441 attatcggaa gagcttgatg cacttggtaa ggcgttagac aatcctaaac gtccaatggt
    73501 tgcaattgtt ggcggctcta aagtttcaac aaaattgact gtgcttgagt cgttatctaa
    73561 gatagtggat caactagttg taggtggcgg tattgccaat acttttattg cagcccaggg
    73621 ctttaacgtg ggtaaatctt tatgtgagta cgatttaatt ccaatagcta aaaaacttat
    73681 ggaagattgt gaaattccag tatcaaaaga tgtagtatgt ggtaaggagt tttcagatgt
    73741 tgctgaggct gaaactaaag catcaaaaga tgttgctgat gatgatatga tttttgatat
    73801 cggacctaaa tctgcccagc agttagctga tattatgaga aatgcaggta cgattgtatg
    73861 gaatggtcca gttggtgttt ttgagtttga tcaatttgct ggtggcacag aaacgttagg
    73921 taaagcgatt gctgagtcta atgcattttc aattgctggt ggtggtgata cattagcggc
    73981 tgttgataaa tacggtatcg aggataaaat aagctatatt tcaacaggtg gtggtgcatt
    74041 tttagaattt cttgagggta aaaaattacc agcagtagaa gttttagaac aaagagcttt
    74101 agaggttata aaacttgcct agaagaacta aaatattagc gacacttggt cctgcaacag
    74161 ataaatatgg tgtattagtt agtattcttg aggctggtgt taatgttgtg cgtattaatt
    74221 tttcacatgg ttcagagaaa gaacatttaa atagagttaa ggaagtacgt gcttgggcag
    74281 aagccaatca aacttatgta ggtgttttga tggatcttca aggccctaaa atccgtattg
    74341 ctgcttttaa agggggtata aagattcagt tgaataatgg agatactttt gcacttgatg
    74401 ctggtttgga tgaaaactta ggtaataaat attcggtggg tattgcatat aaaaagttac
    74461 cacaagaagt gcaacctggt agtattttac ttctagatga tggaaaaata atactaaaag
    74521 ttattgatat taaaggtaat aaaattaata cgaatgtgat tcaaggtggt attttatcag
    74581 ataaaaaagg aattaatctt cgtggtggtg gtttatctgc taatgcatta accaagaaag
    74641 ataaaaaaga tattttaatt gtagcaaaag ctaaagcaga ttatgtggct ttatcatttc
    74701 cagttagtgg tgatgatgta cgtgaaatta agaaattatt aaaacaggta gattgtgatg
    74761 ccggcgtaat ttcaaaaatt gaacgtgctg agtccttagt agagagcgtt attttagata
    74821 ttatcagaga atcagtggga attatggtag cgcgcggtga tttaggtgtt gaaattggtg
    74881 atgcacaatt acctgcacaa caaaaacgtt taattaagtt agctagatca aataatcgaa
    74941 tagttattac tgcaacacaa atgttagaat caatgattat taatccaatt ccaactcgag
    75001 ctgaggtttt tgatgttgct aatgcagtat tagatggaac tgatgcagta atgctttcag
    75061 ctgaaacagc agtaggtaat tttcctggga atgctgttaa aactatgcac gatgtttgta
    75121 ttgaagctga aaaaaaccca attgctaaaa tatctcacca tcgtcttgat gaaaccttta
    75181 ctcatattga tgaaaccatt gctatgagcg caatgtatgc tgctaatcat atgggtgcta
    75241 gagtgatttc tactttaaca gaaagcggta aaactgctat atggatgtca agaattagct
    75301 caggtattcc tattgtagca atgtctgata agatatctac tttgcaaaag gctacgcttt
    75361 atcggggagt tcatccttgt tttttatcca ctaaaaaaga ttggacagag ataaacaagg
    75421 ccgttattaa gcgcttacaa attggagatt ttgtttatga tggcgatact gttattttaa
    75481 ctaagggtat gtataaaaat aagtctggtg gcactaattt gatgaaaatt ttgacagttg
    75541 gcgattcaga gtattaaaat aagagtaaaa atagtcatat ttatataaat aacaaagtaa
    75601 taaactttaa aaaacttaaa aaggagaaaa atatgttaat ttcgttaaga gaattattag
    75661 accatgctgc agctaacaac tacggcatgc cagcatttaa tgttaacaat atggaacaag
    75721 tccatgctat tatgaaagca gcagataaaa ctaatagtcc tgttattatg caaggttctg
    75781 ctggtgcacg aggctacgca ggtgaaccgt ttttacgtca tttgatttta gcggcaattg
    75841 aaatgtatcc acatattcca gtggttatgc atcaagatca tggttctgat ccttctgtct
    75901 gtttgcgttc aattcaatct ggtttttcat cagtgatgat ggatggttca ttagaaccag
    75961 atatgaaaac gccagcttca tttaagtata atgttaacgt gactactgaa gttgtaaaaa
    76021 tagcacacgc aggcggtgtt tctgttgaag gtgaattagg ttgtctagga tcattagaaa
    76081 ctggaatgat gggtgaagaa gatggtcatg gtgctgaagg taaattagat ttagatatgt
    76141 tgctaacttc agttgaagag gctgctgatt ttgttaaatc aactaatgtt gatgcattag
    76201 ctattgctat cggcacttcg catggtgctt ataaatttac ccaagaacca acgggcgatg
    76261 tgttacgtat cgatagaatt aaagaaatcc atgcacgtat tccaaatact catttagtga
    76321 tgcatggttc ttcttcagta ccacaagatt ggttaaagat tattaacaac tttggcggtg
    76381 atatgggtca aacttatggt gttcctgtag aggaaattca agagggtatc aagcacggtg
    76441 tacgtaaagt taatattgat actgatttac gtatgtcatc gactggtgcg attcgtaaac
    76501 acctgggtga aaatacatca aactttgatc cacgtaaatt tttaaaagaa gcaaccaatg
    76561 cgatgagtga tatttgtgca gcgcgttttg aggcatttgg ctcagcaaat aatgctgata
    76621 aaattatcgt atcttcatta gacaccatga gtaaaaaata tctttctatt gagttagact
    76681 ctcaagtaaa gtagacgtat aacaattaat aataaataag gctcgtttct aacgagcctt
    76741 atttatttga tttgataaat atgaagcaat ctaagcgtta tttagttatt gttattgggg
    76801 ggggtcatgc tggtacagaa gcggcacttg cgagtgcacg tatgggagtt agtacgttgc
    76861 tcatttctca taatattgaa acacttgggc aaatgagttg caatcccgca attggtggga
    76921 ttggaaaagg acatttagtt aaggaaattg atgcgatggg tggtattatg gcacacacga
    76981 ttgataaatc tgggatacaa tttcgtacat taaatgcctc aaaaggttct gcagtacgtg
    77041 ctactcgtgc acaggctgat cgtattttgt ataagtcaga gattcgttat gctttagaaa
    77101 atcaagataa tttatcttta ttccaacagt cagtcgatga tttaattatt aaaggtgatc
    77161 aaattaaagg tgtagtgacc caaatgggac ttgctttaat ggcagataag gttattctta
    77221 catcaggtac ttttttaggc ggtattatcc atattggaca acgtaatttt caaggtggtc
    77281 gtgcaggtga tgcaccttcc aacgccctgt caagaaaatt acgttcttat gatttaggtg
    77341 ttaatcgatt aaaaacgggt acaccaccaa gattagatgg aagaacatta gattattctc
    77401 tcatgcaagt acaatcagga gatataccac taccgacatt ttcatttata ggtgttaaag
    77461 aagaacatcc aagacaaatt ccttgctata ttactcatac caacaaaaga acccatgatt
    77521 tgattcgtag tggattaaaa gactcaccta tttttactgg aaatatagaa agtattggtc
    77581 ctagatattg tccatccatt gaagataaag tagtacgttt taatgagcgt gattcacatc
    77641 aaatctttgt tgaacctgag ggactaagta ctaatgaggt ttatccaaat ggagtgtcta
    77701 catcgttatc ttataaagtg caactagatt ttattaattc cataaagggt tttgagaatg
    77761 cacaaatcat acgtccaggc tatgcaattg aatatgattt ttttgatcct agaggattga
    77821 aacaaacatt ggaagttaaa aaaatatcag gattgtattt tgctggacag attaatggta
    77881 ctacgggtta tgaagaagcg gcagctcaag ggttgttagc aggtgttaat gctgcatgtg
    77941 ctatattaga aaaagatgct tggttgccga aacgagatga gtcctatatt ggcgttatgg
    78001 tagatgattt aattacaaaa ggtactaatg agccttaccg aatgtttacc tcgcgtgctg
    78061 aatatcgcct attattaaga gaggataatg cagatgagcg tctcacaccc aaggctaaag
    78121 agcttgggtt aattagtgag gctcgttggc agtcttttca agttaaatat aatgctgttg
    78181 aacaagaaaa aaagcgtctt aaaaatacct ggatacaagc aaacgacact caggcaaata
    78241 cgattttaaa tcaaaatata agtcatgaat attctttatt tgagttactg aaacgaccga
    78301 aagttgatta tcaaatatta agtaaaatag agtccggtaa gccgttttta actgatatta
    78361 ctttaatgag agtgattgaa aatcaaatta aatatgctgg ctatattaag cgtcaactag
    78421 tagagattga aaaatatcgt aagaacgaaa atacagtatt atctacaaat ataaattata
    78481 actcaattaa agccctttct actgaagtta gacaaaaact tgaattacat aagccagaga
    78541 ctattggtca agcaagccgt atccaaggtg taactcccgc ttctatttct attttattag
    78601 tttatttaaa aacacgcatt agttaagatg aatgttaaag gaaactaatt taataggtat
    78661 gaagtttgaa agtgaacaag tcaataaagt tatgaactat attgcgttga ttattaatta
    78721 gaataagact tacaatctaa ttgctattag aatcttggaa caatgtaatt ttatgcaatt
    78781 tgataaaatt aatgataatt aacaattttt aatttggtta attctagatt aaaaccatat
    78841 cagattacct tgctttagat agattatttt aatagccttt ttagaggtta aaaaaaatat
    78901 tgaaattgat gtaataatta ttatgcgata atgacgaata cttgttaata aaaggaagta
    78961 gtattttaag taaaaagaat ttattaggag agaaatgaaa aaaatagggt attttttaat
    79021 aggtttaatt gttattttgg ttcttattat gatgcttgta tttgactcaa taggcaaaaa
    79081 atacgtacaa aagtatgcac aaaatatact tagaacaccg ataactatta gtcaatttag
    79141 tagtagcttc tgggataagc gtttaaatat tgattttatt gaagtgcaga atccaccaaa
    79201 ttttaataat aaagatgctt tttatttgga tcactttgta ttaaaaatcg gggatgatac
    79261 cactctagat ttaattgtta ttgatgagct atcttttgat ggaatgcatt ttattttaga
    79321 gcaaaataag actaacgtga atttagttac actaattgat aacttaggta aaagtagtaa
    79381 taataccact ttatcctcat ctgaggaaac tcatggagtt atcgataaaa gaattaagat
    79441 taatcaattt aatgttatta ataccacatt aaaaattgat acaaaatggc ttaaagagac
    79501 aattaaagtg cctaacatta accttcaaaa attcgggggt aacagtggta ttacacttaa
    79561 taaagttggt caagagttga tggaaattgt gcttaacaat ttagaagatg ctttagagaa
    79621 aaaaggtatt gaactaggag agaaagaaat caaagaaact ctaattcaaa gattatggat
    79681 taataatatt caagaaaatt ttaaattgga caaattcaaa gaatcattag attttagtga
    79741 aactaaaaag ttacaaaatc aagccaaaga tttatttcag aaacttggtt tttaattaat
    79801 tatgcaaata gttgactcgc attgtcatct tgataagtta gattttgtta attttggtgg
    79861 taatattgag agtgtaatcg ctcatgccaa agaattatct gttgtaaagt tcttgtgtgt
    79921 gtgtattgat ttagaacatt ttgatgagat actatttttg gcgaaaaagt acccacaaat
    79981 ttatgcttca gttggtgtac atcctgttaa tacaaaaggc aaagatccaa gtatttgtca
    80041 gcttttaaaa ttagcaaatt atgaagaggt tattgctatt ggcgaaactg gtttagatta
    80101 ttttcatatt gaaaaatcaa tagctgattg gcaacaaaat cgttttaggc ggcatattag
    80161 agcttcgaac caatcaggaa agccaatgat tattcataca cgtaacgcca aagaagatac
    80221 tattaagatt atgcaagagg aaaaagccaa acaaggtgta atgcattgct tctctgaaga
    80281 ttgggaaact gctcagatgg cattggattt aggtttttat atttcttttt ctggtattat
    80341 tacttttaaa agtgctaaag atttacgtga agtggcaaaa aaagtaccaa gtgataaatt
    80401 attagttgaa actgattctc cctatttaac acctatgcct tatagaggta cctctaacct
    80461 accagcttat agttattatg ttgctgagaa gttagctgaa attcgtggtg tgagcattaa
    80521 tgatatcgct aatacaacta caaataattt tgaacaactt tttttaacat gagtgttagt
    80581 tttcaaacta ttgatgaatt ttcacagggt caacgtttag ataattattt acttaaaata
    80641 cttaaaggcg ttcctaaatc tcatatctat agagttattc gtaaaggtga agtacgtgtt
    80701 aataaaggta gaaaaaaatc agaatataaa ttaaacttag acgacatagt tcgtatccca
    80761 ccaattaaag tatctacaac taagtctatg tatacttcag atggtttaaa aaaaatatta
    80821 accaatgcta ttctatatga ggacaagggt ttgcttatta ttaataaacc aagcggcctg
    80881 gcagtgcata gtggttctgg tgttaatgtt ggtgttattg aagcacttcg gcaaatgtat
    80941 aaagaaccta ttgaactggt acaccgatta gatcgtgcta cttctggggt tttgttagtt
    81001 gctaaaaagc gtctagtgtt aaaaaatttg catgagcaat tgaaccaaca taccatagaa
    81061 aaacattata tagctttggt gaaaggggta tggtcaaaaa aaatacacac tattaatgca
    81121 ccattatata ataactcaag atatacaaag gtagatgcta aaggtaaata ttcagttagt
    81181 cattttcatc cacttaaaaa ttttaatatt gagaattttt ctgcttcatt ggttaatatt
    81241 agcattgaaa ctggtcgcac tcatcaaatc cgtgtacacg caaagtatgt tggacatgcg
    81301 ctggcttgtg ataataaata tggggataaa gaatttgata gacaagtaaa attcaaaggt
    81361 ctaaaaagat tatttttgca ctcgaatcaa ctcattttta ttaatccatt gacgaatgat
    81421 attcaaaaag tgaatgcacc tttgcctatt gaattagaag aattcttagc taaattatga
    81481 actttcattt taagactact tcttttgtag cgtatttacg tttaatgcgt ttggataatc
    81541 caattggtat ttatttatta ttatggccaa cattatgggc gttatttttg gcatcagaag
    81601 gatttcctga tttaaaatta ttattaattt ttgttttagg tgttgtctta atgcggtcag
    81661 caggttgtgt gattaatgat tatgcagata gatatattga taaactagta gaacgcacta
    81721 agcatagacc tattacctca ggtgaaattc atcatagatc tgcgcttaaa ttttttgtat
    81781 tattaattat gttggcattt ttattggtat tattaaccaa ctggttaact atccaacttg
    81841 ctatgattgc ggtgctatta gcaattttgt atccatttac taagcgttgg acctactttc
    81901 cacaatttgt gttaggccta gcatttgcga tgagtgtact aatggctttt tcggcaaccc
    81961 ttaatgagat tccaattact gcttggtatg tatttgcagc aacagttatt tggacagtaa
    82021 tttatgatac gatgtatgct atggctgatc gagaagaaga tttaaaaatt gggatcaaat
    82081 caagtgctat tttatttgca aaatttgatc gattaattat tggaatttta caaattatat
    82141 ttttgctaat tttgataaaa atatcaaatg tctttaatct gactatttct tatcatatta
    82201 cgttactttt agttacattg ttaatgattt atcatcagta tttgattaaa aataatgaaa
    82261 actattctta tttacacgga ttcttacata ataattatat aggtatggta atttttatag
    82321 ggattgtgct atctgttgga ctatagatat tccaataaat taaataatac taaaaaattt
    82381 gtggatggta atctttgatt ggttaaataa actaagcctg attgcagagg ttgttatggt
    82441 aatggattta tgtttataaa tatcatagct ctaacaaaaa gactaatgat ttggtaaagt
    82501 acatatctat tagtaattat atttcgatga ttgatatttg taatcttggt aagacttatg
    82561 ttgattgtaa ggttgtttga ctttgtatag gttttatagc tttaaatata tgattaattt
    82621 ttacggtatt aatttagtta gacatatatt gaatattgtt aaagttatat tatctgagaa
    82681 gtacttatta aattaatatc aattgacagg tatttaaaga aaatagcaac aaaaaaaaag
    82741 atattagtat tcataaaaac cttagttttg tggtggatta actaagttat aaggttaaat
    82801 ttaacggttt aacaaaaaaa ataatgagat tttttttgtt aataaaagaa ggtttattgg
    82861 tttcttatat gcctcgtaaa agctcattta tacctatttt ataacgtgtt tttgcatcaa
    82921 cttgcttaac aatcactgcg caataaagtg aataagtgcc atctttactt ggtaggtttc
    82981 caggtacaac tactgaacca gcagggatac gtccatatgt gattttattt gttttacgat
    83041 tgaatatttt tgtggattgt ccaatataga cacccattga aataacagca ctttcttcaa
    83101 taatcacacc ttccactatt tctgacctgg caccgataaa acaattatct tcaataattg
    83161 ttggacttgc ttgtaatggt tccaatactc caccaatacc aacccctcct gatagatgta
    83221 catttttacc gatctgcgcg catgacccca ctgttgccca agtatctatc attgtacctg
    83281 agtctacata agcaccaata ttgacataac ttggcatcat cactgtattt ttagcaataa
    83341 aagatccgta tcgcgcactt gctggtggga ctatacggat acctgcttta ttgaattcat
    83401 ttattgacat gtcagcaaat ttagaaggta ctttatcgaa gtattgagtg aatccacctt
    83461 gcataggtat attttcttcc aatctaaaag ataacaagac tgcttttttc agccattcgt
    83521 taaccttcca attacctata cttttttgtt gtgcaatacg tgctttacca gaatcaagta
    83581 aatgaatagc atcagtaacg gcctgtttta cttttacatt aactgtttgt ggattaagat
    83641 tagctctatc ttcaaaggct ttttcaataa tatctttcat gttagattct actcaaataa
    83701 attaagaatt atatcagtaa tcatgcatta ttgataagtg gtggatttaa attgttgtat
    83761 ttcttgataa aaattaagaa aaaattaaga ttaatgatat gatacttaaa gtataaagtt
    83821 cctcctataa agaagcaaga catgacagat aaaaaaatcc aaatagaaaa cttatatgaa
    83881 gagggtgagc tgtgggtgca gaacctagga gacaaaacca ttcatgcaaa acgcatgaag
    83941 ggaaaattcc gtaatttaaa atggttagct atttttgttt ggttgccatt ttttatgggt
    84001 ccatatctta cttgggacga caaacaggct attctatttg atatagataa caggcaatat
    84061 cacttattta atattaccat ttttccacaa gacatttgga tgttgactat ggtattgtta
    84121 tttttatcta ttttgcttgc aataatgacc gctattttag gtcggatatt ttgtggttat
    84181 ttttgttttc aaacaatttg gacagatatt tttactaaaa tagagcaatg gattgaaggt
    84241 acaccagtac aacgtcgaaa gttagataaa gaaccaatga gttttaataa atttagactc
    84301 aaattggtca aacactctat ttggatagca attgcacttt tttctggtat tacttggatg
    84361 ttgtattttg gtgttacttg gactaattat gttaagggtg atgttacctc tacaacgatg
    84421 gtcatcactg ctattatttc atttggtgct tatgtatttg ctggatttat gagagagcaa
    84481 acttgtttgt ggatttgtcc atatgcgcgt attcaggggg ctatggttga tgaacagagt
    84541 attttaccaa cttatgatta ttatcgtggt gaacgtcgtg gcagacttaa aaaaggtaag
    84601 tttgttaaag gttttggtga ttgtgttgat tgtcatcagt gtgttgctgt ttgcccaaca
    84661 ggtgttgata ttcgaaaagg ccaagagtat ggttgtatta cttgtgggct atgcattgat
    84721 gcttgtgatt tagtgatgga gaaagttggc aagcctaaag gtttaatttg ctatacctcc
    84781 ttagctgaga tgaaatttaa taagccagtt aaggtgtttt ataaacgccc aagggttatt
    84841 atttatgctt cagtattatt tttagcatta tcaatattgg tttatggtat tttaaatctt
    84901 gcaccaatgg atttaaaagt actacatgat agacaaccat tatttgtaca gctttctgat
    84961 ggttctattc gcaataaata cgaacttaaa gttatgaata agacaaataa aattatgcca
    85021 attagtatca gttttagcag taaaattaaa aatctaaaat ctaaaaaatc gttcaagaca
    85081 gtgatgattc caagtggtaa tgttaaatct atttatgttt atttaatagc tttagaaagt
    85141 gatgtaggtt ctgataataa cgttatattt gtggttaaaa gcgaacaggt tactttagaa
    85201 tataaaactt tatttttcac gcctaagagt atatgatgag tattcataga agcccaatca
    85261 tgatggttat gttaatgctt tttatcattt tagtgggcgc aactgtttat cgaattatta
    85321 ttgcacttga aactcatcca ggattggtgg tagaagatgc gtattcaagt ggtcaacgct
    85381 atgcaataac attaaatcat aaaaatcaat tagcacagct tggctgggca ttaaatcttg
    85441 ttactccaga agcagtgagt cataatatta aacaaattta cacggttaat agcacacagc
    85501 atggtaaggc tttgtcagat gctttggtta cagcatattt ttatcgtcct ttagaaaaag
    85561 tacacgattt ttctattaat atgttatttc gtcaaggaat tgataaatat caagcgtata
    85621 taatattacc tttaaaagga cgctgggatt tggtagttga agtggttaaa gaggggttgg
    85681 tacaaagagt ttctaaaaaa ctatttgctc aatagtttta attttcttag gtttgtgatt
    85741 agttaagaga ttcttctttt aaatcctttt aataaaaacc ttagaagatg gaattcataa
    85801 taatatgtat tattatggtt gatttacatt tataaattat cgctatttgt tcttattagt
    85861 gtagtttttt tgctattttt ttttattcaa aacgatatat aatttatcaa cactttttta
    85921 ttgttaccaa tatgataact caataattct ttcaatagca acaattttat taagattgtt
    85981 gctattgaaa ataaatacaa ctaaaatact attatcgctg ttgttagcta tgacaattat
    86041 agtaacaata acaaaggaaa taagtgggat ctatccttta tacgatcttc cttttacttg
    86101 ttataattaa tacttatgtt catgattatg atgatgttca taagtagcca ttagttcatc
    86161 tatttggtca gcaaataaat tattaaattg cgcatctttt aaaatagtat atggcttccc
    86221 tatacaacaa atatgatggt ataggcataa gacttgggtt gattctttca ttactctatg
    86281 aaggtcgtgt gataccatga gtacagcaca attttgttgt ttatgaatat cttgaatgag
    86341 tttatataga tgcatttgac cacttacatc aaggttttga gtaggctcat caaggattaa
    86401 gacatttggc tttgcaagta aggcacgtgt caataatacg cgttgtattt caccaccaga
    86461 taaatttttt aatgctaaat gtagtaatgt ttcaatacct gtgagtgtgg ttgtatcttt
    86521 taaaaacttg gcgtcaattt tttggttaag tttgagaaaa tcaatcactg aaattggaat
    86581 aaactcatta ggaatgaatt tttgtggtgt gtagcttagt ctgatatgtt tagatttttt
    86641 aatcttgcca ttgtcaggag taataagacc aagtagaatt ttaattaatg agctttttcc
    86701 agcaccattt ggtccaatta aggtaatgaa ttctcctatt tttaattcaa agttaacgtc
    86761 atcaagcacc tttttaccat gatggctaag actgatatga tttgcactaa taaggatttc
    86821 tgacatggga taataaggat tactgactag tttttatttt atacgtataa tcctacaact
    86881 gtgtttatgt ttaaaaattg ataaaacatg gaactttatg ccacataaac taattttaat
    86941 ggatggctct gcttttttat tcagagctta tttttctacg ttaaagcaga atttaaccaa
    87001 tcaaaatggg tttcctacag gtgccatgtt tggtgttatt aatgctatga aaagtcttca
    87061 aaggaagtac caggaggcta gaataattat tatatttgat gctagaggta aaaattttag
    87121 gcataatatt tacccacaat acaaagcgaa tagaaaacca attgatggtg gattggtagt
    87181 acaaattgaa cctttatatg agatgattca agccatgggt attcatttta tatgtgtgtc
    87241 taaggttgag gcagatgatg taattgctac tttaagctgt tgcgctaatc aaaataatat
    87301 taagactatt attgcgagtg gagataaaga tttaatgcag ttagtgggta cgaatatttc
    87361 gcaattaaat atgaagggtg ttttacatga tcgccaaagt gtgattgaaa agattggtgt
    87421 tgcaccagag aaaattttag attttttagc tttgactggt gatagtgcag ataatattcc
    87481 tggtgtacct agtgttggtc ctaaaacagc tattaaatgg ctacaaattt atagtgatat
    87541 tttaggaatt aaggaaaatg caatgcagat taaaggaaaa gtgggtgaaa aactacgtga
    87601 taattttgat cttttagatt tatcttatca actagttaag cttaaatttg atgtagtgtt
    87661 gccttgtaat attttagatg atgagccagt aaaaaatatt gataaattgg ctaatttata
    87721 tcagcagtat ggttttttta tgtggttaaa gcaattagat aatgtgtctg tactaaagca
    87781 aaaaagtatc caggttattg gaacagatac aggagttaat aattcggttg atattcttaa
    87841 aggttattca cagatattag tactagattt ggatatattt aatacaatgg ttagtcgtct
    87901 taaaatctta aagacatttg tgtttagttt aaaagctact tcgttagatt atatgaatgc
    87961 ttctattgtt ggttgggtat ttttaattga taaggatagt ttttatgtgc ctgttaatca
    88021 tgattatata gatgcgccaa agcagttgaa ttttaatgat gtgcttaatc aactaaaacc
    88081 aattttagaa gatgtgtcta ttagtaaaat tggacaaaat ttaaaatatg atgcacatat
    88141 tttatctaat tataaaattg atttgcaagg cattagtgat gatgttatag tgaagtctta
    88201 ttgtttaaat tcagttgcta caaggcataa tatgaatgat ttgagtgaat attatttaaa
    88261 ttatcaaacc attaattttg ttgatatatt aggtaaaggt aaaaaacaag ttacttttaa
    88321 tcaagttaat gtagaaattg ctcttcttta tgtttgtgaa aatgtgataa taacaagttt
    88381 attaaatcat atgctagatg aagaaattgc tcaatatcct agattagtta aattatatca
    88441 aaacctagaa ttgccattga ttaaagtttt attgtgtatg gagcgtaatg gtgttgaatt
    88501 agatgtgaat atactaagta ctcagcagtt agatattacg caacaaatgg aggatattaa
    88561 gaatcaagta tttgaactgg cagataatgt gtttaacctt gaatctccta aacaaatcca
    88621 acgaatttta tttgagtcta aaggtttagg tctaattcct ttgagaaaaa ctcctaaagg
    88681 tgtaccatct actaatgagg aagctttaaa acttttagac catccggtgg tagatttaat
    88741 attaagttat cgaacattag ctaaacttaa ttctacttat cttgaagtac ttcctaggaa
    88801 gattgattta aatacgcata gacttcatac ttcttataat caggtagtaa ctgctacagg
    88861 tcggttatca tcaagcaatc caaatttgca aaatattcct attttctctg aacaaggttc
    88921 gtgtattcgt ggtgcattta ttacaggtaa aggcaatgtt attatttccg ctgattactc
    88981 acagattgaa ttaaggatta tgacacaatt atccaaagat caaaacttat tagaagcttt
    89041 taataatgat aaagatgtac atagcgaaac ggcatcaact atgtttaata taccaattga
    89101 tgaagtaaca tcagaatatc gtaggcgcgc caaagcgatt aattttggtc tgatttatgg
    89161 tatgagtgca tatggattag caaaacaaat tggtgtatct agaaccaaag caaaacaata
    89221 tatggatact tattttgata actatcctag tgttctatat tacatggaca atatcaaaga
    89281 aattgcaaaa gtacaaggtt atgttgaaac tattatgggt agacgtttgt atttaccaca
    89341 aattaatgcc aaaaataaga tgttacaaca acatgcactt agaactgcta ttaatgctcc
    89401 tatgcaaggt tcttcagcag atatcattaa aaaatccatg tttgatgttt acacatggat
    89461 tggacaagat aatccagata ttagaatgat tatgcaagta catgatgagt tggtatttga
    89521 ggtaagtgcg tcaaaagctg atgaattttc ccgtaagata caagctttaa tgtcaaatac
    89581 ttatttattg gatattcctc ttaaagtaga tgtaggaatt ggtaactctt ggaaagaggc
    89641 acattaatga tttaacttac aaattttatt ttgtgatgtt atttcttgat tttaatcagt
    89701 tatttagact cctttgtaaa aaagatgtct tgaaaaataa aaattttcca atcctagatt
    89761 tagagttggc attaaaaaag caaaaaataa ttgtattttg gtagagtgta gagaaataca
    89821 tattatgggt cgattattac ttttgtaatg tcaaaaatga caatgagtat aacaatcgat
    89881 atcactaaat attattgata aagttaataa aattatatat agtaatcttt ggattattat
    89941 attaaaaaag aattagatct gtatgtaaaa aataggtata tttaaatttt ttttagatat
    90001 attacagtat attaaatata ttagcattat ataggtgtgt gataaattag acgtttaaca
    90061 ttttatttta aagagttaat tgtataaaaa tagtaaattg acttattttt aaatcaaata
    90121 attatcctaa tttagaaggt gaatttttag ggttagatat cgaaaaggtt ttgagataaa
    90181 aaagataatt atcattcaca agaatgatag ttttacgtta aagaaataga aatatatata
    90241 aaatcaattt aaataacttt aaaaatataa ataatttttg cttaaattgg tatctatcta
    90301 tttgtatatt gaggattttt tctattttat gtcttatttt ttctatttta tgtcttattt
    90361 tttttgtagt ttatctaatg tttataatgc ataatattgg aagaattagt tacagttttt
    90421 aaatctaaca cataaaatag aatttatagt acaagaatac tgaagcgatt gatttttgca
    90481 tttagaaaat acagaagata attatgaaac aactattaca acaattgtta gtacaatctt
    90541 tagaagtatt gatggacaat aatatacttg aaagtatgcc tgagaatatt cgtgttgatc
    90601 attctaaaga taaagctcaa ggagattttg cttctaatat tgcgatgtta ttgtctgaac
    90661 aagcacagtg ttcttctaaa gtattggcac aaaaaattaa agctaatttt ccagattctg
    90721 ttgatgtgga aaagattgag attgtaggtc ctggttttat taattttttt atgtcacaga
    90781 gttcaaacgc tttagtggtg gaggatatta ttaagcaagg tggaaattat ggtttgtcta
    90841 atattggtat ggggcaacga gttttgttgg aatttgtctc tgctaatcca acaggtccac
    90901 ttcatgtagg acatggtcgt ggtgtagcgt atggtgcagc ggttgctcat cttctacgtg
    90961 cagtaggttt tgaagttgat tgtgaatatt atgtgaatga tgcgggtcgg cagatggata
    91021 ttttggcgat ttcggtttat ttacgctatg ttgaaactga acaatttcca gataactgct
    91081 ataaagggga ttatattttt gatattgcta aaaaaattag tggtgtcaaa aaacttgata
    91141 tttttactaa tacttgtaaa gatacttccg aatggaaggt ccagaaaaat agtatcgata
    91201 aggaaagata tattgatgat ttgattgcta attgtaagct ccaattagga agtgattata
    91261 gaaaagtctt tgattttgcg attaatagta ttttgagtga tattaagatt gatttagctg
    91321 attttggtgt tgaatatcat cagtggtttt ctgaacagtc tttagtggat agtggcttga
    91381 gtgaagaaat tgttaaaaaa ttacaagact taggatatat ttatgaaaaa gaaggtgctc
    91441 tttggtttag aaccactgat tttggtgatg atttagaccg tgttgtagtt cgtgataatg
    91501 gaatacatac ttatttttcc tatgatattg cttatcatct tggaaagttt gaacgtggtt
    91561 atgataggat tatcaatatt tggggcgctg accaccatgg ttatattgca agggttaagg
    91621 catcaattaa ggcgcttaat tacaatcctg ataagttgga aatcttattg gtacagtttg
    91681 ttaacctttt tagggatggt aaaaaggttt ccatgtcaac ccgtagtggt tcatttatta
    91741 ctttaaaaga attgcgtgaa gaagtgggta atgatgtagt acgttttttt tatattttgc
    91801 gtaaatcaac acaacatatg gattttaacc tagatttagc taaatcaaaa agtaatgaaa
    91861 atccagtatt ttacattcaa tatgcttatg tacgtatttg ttcagtttta aaacaaggta
    91921 tgccttttat ggcagatatt gatttattgg tattaaataa tgagttagaa actttattaa
    91981 ttaaagaact taatcgctat aaagatatct tacaatcatc tgcacttaat tatgagccac
    92041 acgtattagc ttgttattta cgtaaattag ctggctattt tcacagttat tataataact
    92101 gtgagttttt ggtagatgat gataaattga gaaattcaag gttattgcta attacagcag
    92161 ttcagcaaat attggcgaat ggtttaaatt tattgggaat tagcacacct aattcaatgt
    92221 gaatgaccaa aaacaaaggc gacaagcatt agacgttagt caatctttta ttattcaagc
    92281 gcctgctggt tcaggaaaaa cagagttatt aacgcaacgt tatttgaaat tgttatcagt
    92341 cagtacttcg cctgagagtg ttattgtgat gacctttact aaaaaagcgg taagtgaatt
    92401 gaccactcga gtgattgaat cattagaatt ggctcaagga aatagaccaa aagatccaca
    92461 taaacaaatt atttatgatt tagcttttca agtattagaa agatctaagg agcttgattg
    92521 gcaattatta aatacacctg aacgatttaa gattttaacg attgatagtt tatcaagttt
    92581 gattaccagt cactatccaa gtaaaaatca attagtgcct aagaaagtta tatcgcaaaa
    92641 ttgggcacga tattctatgt attctcaggc cgctaagcaa actttactag cgattaatga
    92701 acttgaatat caagatagtg ttgagtcgat tcttttatat ttggataata atattgatag
    92761 attttatcag ttgattacgg acatgttggc taaaagagat cagtggattt tgaaattgta
    92821 tcaacatggt acgcttaata ttgaaacctt gcggctaagt tctgaaaagg ttattattca
    92881 acatttatct ctgttaaaaa atgaagtaga atattatttt gatccaattt tttttaaatt
    92941 gttaaaatat aattctaagc tagaatttgc tcagattaaa gacgtgccag atgccactat
    93001 taaatcgcta gaagtttgga aaaatttgag tcggttatgt ttgacggtac aaggtaagtg
    93061 gcgttcatca ttgaataaaa ataatggttt tcctgcagag ttaaaaatgc aaaaactagc
    93121 tattatcaaa atatttcaat ctttatctag tcatcaacaa ttaagagagt tattagcagg
    93181 ggttgaatat ttgcctgata ttaatttttc aactgatcaa attaatgttc tgcaagatat
    93241 tgcacaagta ttaaagttgg ctgtttctca attgaaaatt ttatttgatg ttaatcaaac
    93301 gcatgatttt attcaagttt ccttggatgc agaccaggct ttagatgaat atcatgtcag
    93361 tgatatagcg ttattcttgg ataataaaat ccagcatatt ttgattgatg agtttcaaga
    93421 tacctcagtt atacagtttt ctttattaga aaaattaatt gctaattggt actcaggtga
    93481 tgggaaaaca ctatttttag taggtgatcc tatgcagtct atttacttat ttaggcaatc
    93541 tcaggtaggt ttgtttttac aagttagaac gcgaggaatt gctaatatta aacctgaatt
    93601 cttacaactt catactaatt ttcgttcctc tcaatctgtg gttgagggaa ataatgaaat
    93661 attctcaaag atatttccta atcaggaaga agcttataag ggcgcaatta agtatgagta
    93721 ttcaaaggcc tattttactg ctgaaagcaa aagagctatt aatttttacc catttgcata
    93781 taaacgttat gattttgagg cacaacaagt attaaaaatt attcagaaca atccaacaaa
    93841 agagattgcc attttagtta gaaatcgttc acatttaaat aacattgtac ctgttttaaa
    93901 gcaggctaat attaattttg aggcagtgaa aatacttcca ttaaaagatg atttatttac
    93961 ccgtgatttg cttagcttaa ctcgggcatt aatatattta ggtgataaac ttgcttggtt
    94021 agctatttta agagctcctt ggtgcgggtt attgttagaa gatttacttg tattatcaca
    94081 aaataatgaa cgtgttatct ttgatcttat tcgagatgat cagacattac aaggtttgag
    94141 ttcagatgga cgtattcgtg tggataattt tgcctatgtt ttaggtaata ttgttaatca
    94201 acaatctaga tttagtttta ctcaagtact tgaatttgcg attaatcaat tagtacctcc
    94261 aaattcttta tctgttaaac agtctatgat taaaactcag ttcttgcaaa ttatttatga
    94321 ctgtgagttt gagcaacagt tggatattga aactattaat aaaatgttag atgaattgta
    94381 tacacctagt gtgaatgtat tgaatgcacg aattaagtta atgactattc atgaagcaaa
    94441 aggtttggaa tttgagttgg ttattattcc tgggttggga agagtgtcac aaaataataa
    94501 atcacctatc attcatttac aagaatttag taatcagtct ttattattag cgccgataag
    94561 gtcttataca caattaaatg atagttgtac ttatgtttat ttaaagcata ttaaatcaca
    94621 acaagatagg tttgaaacca tgcgtttatt atatgtagct atgacacgtg caaaatataa
    94681 aatttattta ttagcaacat taagtcaaag taatcaagcc attagaaaca cttttttaaa
    94741 attattagaa cctatatttc agaaccggtt tgaccagctt aagtcgtcag tcattgagga
    94801 taataaacaa cccatacgag cgccagagtt agtacgttat attaagccta tagaatataa
    94861 taatttgctc gatagaagta agaaaaaaat gaactttcag cttaatgttg atttgcaata
    94921 taaaagctta cttggtattt tattacatca atattatgca aatgaattgt tctcgccaga
    94981 taggcaaaat ataagagtaa gattggttga attcggtatt agtaatatgg atatagatga
    95041 ttctatagac tttattattg atatgcttaa tttaacgaaa caagataaat acttttcgtg
    95101 gttgtttaaa caaagagtat caacccaggt tgaagtagaa tttattaatg acaaacgtaa
    95161 cattattatt gatcgattat ttattgatga aggcattttg tgggttattg attttaaaac
    95221 tgaaagacaa gtaaataatg agtcaatagt acaatttata caaaggcaaa aaattaaaca
    95281 tagccatcaa ttattatttt ataaagtgac tttatcagaa tgttattcaa tggaggtaaa
    95341 gtgcgcttta tattgtccat cagtacaaaa attgattaga attgactaaa tatttattct
    95401 tttattttta atgttactta gttgatatga aattaatatt atgtttttct actaaatata
    95461 gagaagttat actaataagg agaatacaat ttaacagttc ttatattggt tcttaatgaa
    95521 tctgtttagt ttttctaata ttgtttaact gatgataact ttatgctatg ttgtcatact
    95581 taacaatact tttattaaat acatcgccag taatttgtaa tagatctgcg tagacaatat
    95641 tatataaaaa ctataataat agttttagtt atgccattta ccaatatcga tcaccatatg
    95701 tataaattac ttttcaattt catgatagaa ttttcaatca aaaaaataca ttatctacac
    95761 ttaatttaac agcgtattct ttaattaagc agctttttac ctggataacg ctataaaaat
    95821 acaaattaaa acatgaaaaa gtataaagcc tgatatttaa tgaataaatt gtttcaatat
    95881 tattgaaatt agcgattata ttgtttttat tgggtgaatg acgtgaatag ggttaggtgt
    95941 tttatcgagt atatttttag tttttttact aaaatcaatc atttttcttt ttatgaacta
    96001 ctatgagtga ttgtttattt agagttaact tgttatttag ataaatgagt gtgttaattt
    96061 gtatccaagt caattgaaag attttttggt ttaaatagtt tgaagataga tgttatattt
    96121 gttttgtatt tggttttgaa tttaaaccca atatctattt acaaagatgc gacacaaggt
    96181 taagttagta atattaaatc aaactttaag tttaggtatt gcgtactaat ttaaatttat
    96241 acgaaagagt tgatgattcc tagttataat ttttaaacaa agcgttaatc attgctactg
    96301 catcacatcc agcatcaaat gcttgttgtt ggttataaag gtcaatacca ccaataccaa
    96361 caattggtat gtgtaatatt tgttttgctt tagtaattac attaagtggg caatgtggtg
    96421 cattaggttt agttttggaa tcgaatagtg caccaaaggt tacataatta gcaccttgtt
    96481 tttgagcttg aaacgctaaa ttaatatcat tatagcaaga tataccaatg atagaatcaa
    96541 tgcctaattg ctgtcttgcc tgttgtatcg aaccatcatc ttttcctaaa tgtacaccat
    96601 cagcatggac tttttctgtt agattaatat cgtcatttat gataaataaa gtattatgca
    96661 ctaaacatag ttgacgtaat acatatgctt ctttgagttt catattgttg ttattagttt
    96721 tgtgtcgata ttggagtata ctgatatgat gtttgttgat gacccatctt attagaatag
    96781 aattaagtga aacatctggg gttattgcat atatatggct aattttttta ttaaatacca
    96841 tgtttgactc tcagttgaga catagtttat taagtgtagt ttttattata gtaataattg
    96901 gtattatatg gttttttata ggattatttt tgttttcatg ttctgttcag gaagataaac
    96961 agaaaccact attaatagat aatcaaactt cttttgaagg agtgacttat cttgaaagaa
    97021 ttgataattt ttctttgcag gtatttgata ttaaagcgga attgtcgtat tttgttaaag
    97081 ctaaaagtta ttttagtttt aaaaacttac cagtattatt aatagaaccg aaagtaacat
    97141 tttatgatgc aaaaggtatt aaaaattatg tattaaattc taaacgtgct cactatgttg
    97201 acaataatgg aattaagttt aaaggggaag ttggtattca tttcagcaat gggtttaatc
    97261 ataagataaa tacagaagaa ttattagtcg gtattgagac tagagatttg atgagtaaga
    97321 aacaagtgac ttatttaggt gaaaccgtta agattatatc tcaaggtata cagatacggt
    97381 ctaaagatga tataataaaa ttaataggta atattaagat caatcaaagg gatggtcaac
    97441 aaatattgac taaagacttg tacattaatc agattgaagg tcaaaaacat ttttattcaa
    97501 aaaataaaat tgtttacatg tttcagaaag ataaaattta tgctgatagt atagatataa
    97561 atgaacaaaa acaaattata gaattattag gtaaggtaaa aattatgaaa gactctggtt
    97621 ctaaaattag tactaaaaat ttgtttattg atcaatcaaa tggtttggaa atatatagga
    97681 ctaaagaaaa agtacactac caatctaata ctgctgatat tcatgctgtt ggtatgattt
    97741 atgatgtaat taagcaaaaa ataaagttga caagtgatgt gatagggata ctataaataa
    97801 gattattttt aattaaaaat ctctgtaaat aatttttata ttctcaacaa tcctaaccaa
    97861 attagtctta cttttaaggg cgctagtatt taaatataat atatatgact gaacaagaac
    97921 ctacacatct taaagacaaa gcacatctaa tgtaatattg gtactgaata tagcttagat
    97981 attcttaatt catatatcta tatgggtatg ttgaaatatc cccatagagt gatataggta
    98041 aaaatgacca taggtataat ttttggtttt atattgaata taggattaca atatgtcaaa
    98101 attagttcca ccacatggag gtgataaatt aaagccttta gctttagaag gtaattcttt
    98161 gatggctgag ttagaaaaag caaaattatt attaaaagtt agctgttctt caagagaagt
    98221 gggtgacatt attatgatgg gtattggtgg ttttacgccg ttagaaggct ttatggataa
    98281 tgtaaattgg cagagtgtat gtgataatat gaccatgtca agtggtttat tctggccaat
    98341 tcctattact ttgtctacta atagtgaaga cattaagcag ggtgatgagg ttgctttggt
    98401 taatggagaa acggatgaca ttattgctac tatggttgtt agtgaaaagt attcgattga
    98461 taaatctcat gagtgtaata ctgtttatag aacaactgaa atggcgcatc caggagttgt
    98521 aatggtaatg gctcaaggaa aatacaatct tgctggttct atcaaggtat tatcagatgg
    98581 taactttcct gaaaaatatg gcagtttata catgactcct atggaaactc gtgcttattt
    98641 tgatgacaaa ggttggaaga caatcgcagc atttcaaaca cgtaatccaa tgcaccgttc
    98701 acatgaatat ttagctaaga ttgcagttga gatttgtgat ggtgttatga ttcactcagt
    98761 attaggtggt cttaaggatg gagatattcc tgctgatgta cgttcagaag caatttcagt
    98821 attaattaaa aattattttg tagataacac aatcttacaa tctggttatc cattagatat
    98881 gcgttatgca ggccctcgtg aggcattact acatgcatta ttcagacaaa attatggttg
    98941 ttcacatctt atcgttggtc gtgatcatgc cggtgttaat gattattatg gtccatttga
    99001 tgcacataat atctttaatg tgattgctaa tgatgcgtta gtgacaaagg cattaaagtt
    99061 tgattggaca ttttggtgtc ataaatgtgg gggcatatct tcaatgagaa cttgtcctca
    99121 taattcagaa gatcgcgtac tactgtcagg cactgaagtt cgtaagatac tttctgagaa
    99181 taaagagttg ccagagactt tttctcgccc tgaagtagct aaagtgttac aagtatatta
    99241 tgctagtatt aaagatgaag ataagataga aattaaattg aatgaccatt ttactaaata
    99301 gtgttgaatg tcttaacttt gtatatctaa agagatacgc tgtaatatta ccataaagca
    99361 ataggtttga ttttgtgagc taactttatg caagtataat aagtcgaatt ttgacaaaat
    99421 gccatttaag tgttgaaaca aaaatagtga atgctaattg aaaaaaagtt ggcacaattt
    99481 gggatgagag tgatttaact taaggagaag aactaatgat cgatatcaat tcaacaccaa
    99541 ttgctagctt attagcagaa ggtatttcat atacaaatat gcaaatgtac gtagttatta
    99601 tgattgccct agtgattatt atgacagttt tagatttact gcataaaaaa agttcaatct
    99661 acttttttag tgcatcagca aaagctgaaa aggatttatt tgcaggtaat gcgccatgtt
    99721 cattaggtaa agaagaagat agacttaaaa tattaagcgt tgctgataaa gtaaatatat
    99781 tggcaagtac ggttgtagta gatgtttcaa cagctggtga atttagtaat ggacttcgta
    99841 gattggtgca tattttaacc atgtggggtt ttattttctt taatgtagca actataatta
    99901 ttatttttgg tgcacaagaa actcagatat tagcacaagt gtggaatatt ggtgcaataa
    99961 tgctgtttat tggtacattt tggtattggt ttgggtttaa agtagatagt caagtggaag
   100021 gttattcttg gacaagagtg gttattagaa gagatatgtt tagtttgtca ttaatggcaa
   100081 cttcggtatc tgcgctaggt tggaatatat atggcggtgg tactggtata tggtttattt
   100141 tagttctttt agctactata tcactatttg gtggtgtgta ttggtctaaa ttttctcata
   100201 tgttttttaa gcctattgct gcatacaata agcgaattat taaagctaat ggtacaaatg
   100261 agaatttgcc tcatgagaca agaaatgatg tgtggcaaca aaatagacat tcaatggagc
   100321 ttctaaaaga tgctcccatg gatatgggcc ttggtattaa gcgtgaagcg cctaagcatt
   100381 attaatatta attaaataag aagagaggaa aataatatgc caacttttgt atatatgact
   100441 cgttgtgatg gttgtggaca ttgtgtagat atctgtccat ctgatattat gcacattgat
   100501 gataaatatc gtcgtgctta taatattgaa ccaaatatgt gctgggaatg ttattcatgt
   100561 gttaaagcat gtccacatca agcaattgat gtacgtggtt atgcagattt tgcgccatta
   100621 gggcacagtg ttcgtgttat tcgtgatgaa gagaaaggca ctattgcatg gagagttaaa
   100681 ttccgtgatg gacgtgtaaa gaatttctta tcaccaatta cgactcagcc atggggaact
   100741 aagattcctg atcttagaaa tgagcctgag cctagtaatg atatgcgtaa ctcacagttg
   100801 ttagcatttg aacctaaata tattcgtatg gatgatggtg atattcatac attagaatct
   100861 aatggcttga aatttaaaga aggagtgtac tactaatggg tattaaaaca attgtagaag
   100921 acaacattga tattttagtt gttggtgctg gtttaggcgg tacaggtgct gcttatgagg
   100981 ctagatattg gggtcgtaat aaaaaaatta taattgcaga aaaagcaaat attaatcgtt
   101041 caggtgctgt tgctcaaggt ttgtatgcga tcaactgtta tatgggtact cgtttcggtg
   101101 aaaataatcc tgaagaccat gtgcgttatg cgcgtatgga tttgatgggc atggttcgtg
   101161 aagatttatt gtttgacatg gctcgccatg ttgactctgc agtacataag tttgaagagt
   101221 ggggtcttcc actaatgaag gatcctaaga gagaagatat tggtgcttat atgcgtgaag
   101281 gtcgttggca gattatgatt cacggtgaat catataagcc tattgttgct gaagctgcaa
   101341 ccaagcaagc tgataaagtt tacaatcgta ttatggttac ccatttatta atggatgatg
   101401 agaaaaagaa tcgtgttgct ggagctgtgg gttttaatgt acgtactggt aattaccacg
   101461 tgtttaagtc taagactact attgttggtg ctggtggcgc gtctaatatc tttaagcctc
   101521 gttcagtcgg tgaaggtatg ggtcgtgtat ggtacgcacc atggtcttct ggttctgctt
   101581 atggcttatt aatcgaagct ggtgcgaaaa tgacacaaat ggaaaatcgt attgttcttg
   101641 ccaggtttaa agatggttat ggtcctgttg gtgcatactt tttacatctt aagacttata
   101701 ctcaaaatgg ttatggtgat gagtatgagt ctaagtggtt tccagcatta tcaaaaatgg
   101761 taggtaaaga atatttagat acagaaggtc aacatttatc tcataaacca attccaactt
   101821 gtttgcgtaa tcatgcattt attagcgagg taaatgctgg tcgtggtcca attcatatgg
   101881 taacaatgga agcatttaaa gatcctcatc tagaagaagt tggttgggaa aatttcttag
   101941 gtatgactgt tggtcaagca gtactttggg ctgcaacaga cgttgatcct aaatatgaaa
   102001 atcctgagtt aacaacttct gagccatatg taatgggttc acacgctact ggttgtggtg
   102061 catggtgctc aggtcctgaa gatatttctc ctgatgaata cttttggggt tataatcgca
   102121 tgacgacggt agatggtttg tttggtgctg gagatactgt tgggggtacg ccacatgcgt
   102181 tctcatcagg ttcatttaca gaaggtcgtt tagctgctaa ggccgcttgt aagtatattg
   102241 atgatggtaa agcagaaggt attgttgtat ctaacaagca aattgctgag cgtaaagaac
   102301 agatttataa gcctttagag aattatacaa ttgggcgtaa tgaaattgtt gctggtacag
   102361 tatctccaag ctatattctt ccaatgagtg gattgcaacg tttacaaaag attatggatg
   102421 agtattgtgg cggggttact gtttcttata taactaatga taagttgctt aatataggat
   102481 tgaagaagtt agctatttta gaagaagatt tagaacatat tggtgcagaa gatcttcatc
   102541 agttgatgcg tggatgggaa ttaagacacc gtcatcgaac ttctgaatgt gtgactcagc
   102601 atacattgtt tcgtaaggaa actcgttggc ctggatatta ttatcgtgga gatgctatga
   102661 aattagatga taaaaattgg catgtattaa cagtttctca tcgtaatcgt attactggtg
   102721 aatatacact agagaaggca ccttgttacc atttagttgg tgaaggggat gaaaagtaga
   102781 ggttcaatta aaattttgat tttaataaga agaccaatat ttatatgttg gtctttttta
   102841 tttattgtgt attttaagaa aaaacgtttt tattggggtt attgaatcaa tgaacattat
   102901 tgataaaaca gatgaggaaa ttttagcaat tgcaaatcca atgtggaata acttagttaa
   102961 atattctaat aatggtaatt acggtgcctt tagtcgtcat ttttcagagg attttttgcg
   103021 tggtgctaat gaaattgaaa tgggaaagca atttgctcgt agtgaattaa ctaagggtct
   103081 tgaaaaaggc gcaggatgct taggaatgat tcgccgtggt caatatgtaa ctgtattgta
   103141 taaacaaacc cattctaaaa aagaaggcga gtatttagga agactggtac ttggttatga
   103201 agatgatgtg gtcaaaattt ttggtacaac aattttttag aaattgtgga taatattatt
   103261 aaagagttta aatatgttga gctgatctat aaagttattg ataaaaagac tggtaatatt
   103321 tttttatcaa ttgagtatcc agtcggctat gtgcatggta ttaatgatac attaggtaaa
   103381 gaggttatta atgaattaga gggtagaaga caaggagatg ttattgaggt tgagattgat
   103441 gtagataaac tctatgggat tcgtgacgaa tctttagttt ttattgataa aatagaaaat
   103501 attcctcata aatatcagaa agttggcact aagattgtta tggagaattc taaaggagaa
   103561 tctaaggatt ttttggtaac taaagtggat gataaaacag ttactattga tggtaataat
   103621 cctctttgtg gtcgtgaggt taggtttatt cttgacattc atttggttcg tgatgcaaca
   103681 gatggagaga tggaagtagg tggtatgaca gatgaacaac cagatataga acaattatta
   103741 acagtgcatt aatcatgagt attgattttt taggatcaga aataaagacc attcaaaatg
   103801 cagttaatca gcgatggaaa aaagaaaata ttaatgttaa tttagctgat attgaaatta
   103861 ctaaagaagg tgaattaaca cttgttccag cggctgtttg ggaagataaa aactcaactt
   103921 ttattatttt aaagataggt atattctctt acaaaagttt tttttattat ttaactgata
   103981 agcgttttga tactggtgtt tctgagtata acgatttgta tgaatgtgcg aatacattgt
   104041 taaaagcgca agcagatttt attttaagtg aacataccaa agacttaaat ttacatagtt
   104101 ttaaataata tttttttaaa acttaaattt taaaaaaaga catactacat actatgtatg
   104161 tcttttttag gaaaattaat ttttacaaaa ggggtataat catgattgca acgatattga
   104221 taattttgat taatggattg attgcaggtc cagctgtatc tttatatgga tctcctaccg
   104281 tatcaccagt aatagcagct ttatgggcgt ctgaaccctt tccaccaaag tgaccgtctt
   104341 cgatatattt tttagcgtta tcccatgctc caccacctgt ggtcattgat attgcaacaa
   104401 aaataccggt tgtgatagaa ccgattaata gtccccctaa cgcttcagcg cctaataata
   104461 aaccaaccac aactggaaat gcaattggta ggatagaagg tagtatcatt tctttaatgg
   104521 ctgatttggt taacatatca accgctttag aataatcagg tttttgtgtg taatccatga
   104581 tacctggtat ttctttaaat tgacgacgta cttcgttaac aatcccacct gcagcacgac
   104641 caacagcctc cattgccatt gagccaaata agtaaggtac caacccgcct aggaataaac
   104701 caataataac tttgtgatct gagaggtcaa atggtatatt actaccaaat ttaattgaaa
   104761 tctcattggt aaaatctgca aataaaacta gtgttgctaa accagcagat ccaatcgcat
   104821 accctttggt tactgcttta gtagtattac caacagcatc taaaggatcg gtaatattgc
   104881 gaattttttc tggaagttta gccatttctg ctataccccc agcattatca gtaattgggc
   104941 cataagcatc cagagcaaca ataacgcctg tcattgacaa catagcggtt gctgaaattg
   105001 caatagcgta taagccgcct agttcatacg caccccaaat acttgtacat actgcaagga
   105061 tagggaaggc agtggatttc atacttaggc caatgccagc aataacgtta gtgccatcgc
   105121 ctgtgagtga cgcttctgca acatgttgta caggactata ttgagttgac gtgtaatatt
   105181 ctgttactac aaccataaca gctgttagtg ctaaaccaat gagtgatgcg tagaataaat
   105241 tcattcccat attcatgtta ttagtaataa agtagaaagt aattgcagct agtactgctg
   105301 aaacggttag gcctttatat aaagcaccca tgatagaacc actattatca gagactttaa
   105361 caaaaaaagt acctataatg gatgcaataa ttgaaattgc ccctagagct aacgggtata
   105421 aaatagcatt atcacctaag cctaaaacac ctgccagcat catagttgca ataatagtca
   105481 ccgcataagt ttcaaataag tcagcagcca tacccgcaca atcaccaacg ttatcaccaa
   105541 cgttatcagc gattactgca ggattacgtg gatcgtcttc tggaatacca gcttcaactt
   105601 taccaacaat atcagcacca acgtcagcac ctttagtgaa gatgcctcca cctaaacgtg
   105661 cgaaaattga aatgagcgaa ccaccaaatg caagaccaat cagtgcgtgt aatgcgtctt
   105721 tttgtgcaat accgtattca atcataccgg cgtagtaacc agagacacct aatagtgcta
   105781 agccaacgac taacatccct gtaacagcgc cacctttaaa ggcaacttga aaagcagcat
   105841 ttataccatt atgagctgct tgtgctgttc tagcattaga tttaactgat acattcatgc
   105901 caatataacc tgttatacct gataatactg caccaactaa aaatccaaga ccaactgtat
   105961 agcctaaaaa gtaagtaata atgataagta agataacacc tgctatagaa atggttgaat
   106021 attgacggtt taagtaagca cttgcgcctt gtgcgattgc gtttgaaatt tctttcattt
   106081 tgtcattacc taaaggttgt ttgttaatcc aggtaattgt caataagcca tataaaacag
   106141 cgacagttga tgctgaaatg gcaaggataa gaattatgtc cattatttta ttttctcctt
   106201 tttagttatg tgtgtgaatt ttattcaaga ttgattatag ttaataattt cctatatagt
   106261 gaaatgataa ttaaaataat tttatagaat taacttattt taattatcat ctagagtgtt
   106321 aacaaatact agtatttgtt tcagtatttg gttttgatac catgatcaaa ttttatctag
   106381 tttagatata atctaagttt taagtagttt tttaataaaa tttaggctca gcttgtttta
   106441 ccgaaaatat ttgaggtgta attatagaag taatacaaat tgaattctgg gaaatagcat
   106501 cattttgcaa ttaggtgtta tctaatggat ttaagatgct tttcgataaa acagtaaatt
   106561 ttaattatta gttaataaac tgttattttg agttatattt tgaatatata tattttatat
   106621 tttgatattt ttttcaagaa ataggatgaa atagtatgtt aatttttctt gaactagttt
   106681 taatcataag aaattaaact gttatatata cgatccttaa cttcatcaag cgtacctata
   106741 ccaatagctg cagcgtattt aggtgcatta ctatctttat ccatccagga ttggtagtaa
   106801 ttaactagtg gttgagtttg gttatgatat atatctagac gtgatcttac tgtattttcg
   106861 gaatcatctg agcgttgtac tagtttttcg ccagtaatat catcaattcc ttcaacttta
   106921 ggttgattat aggtgatatg ataagtacga cctgatttta ggtgagtacg acgacctgac
   106981 atacgggcaa taatttcttg atctggtact tgaatttcaa ttacaaagtt aattttaaca
   107041 ctatcttttc ttaacgcctc tgcttgagtg attgtacgtg gaaagccatc aaataaaaag
   107101 ccatttttac aatcactgtg ttggattctt tctttgacta agttaataat aatattatca
   107161 gaaactaaac cgcccgaatc catgattttt ttagcctcaa tacctaatgg tgtgcctacc
   107221 ttaacagcaa cgcgtaacat atccccagtt gaaatttgag gtatcgaata tttattacaa
   107281 atattggttg cttgggtacc cttacctgct ccaggggggc ctaataaaat tatgttcatt
   107341 tttttccttg tttgttatat ttaatgtttt tagctaaaat gaaaacatct tggctattga
   107401 ttttttatta aaaaatcaaa aaatatttgt tccctttagg gaaaaggttt aaactccgaa
   107461 tggaggtaat tttttatcca ccattaattt tttcattact acataatcag gtaaaccatt
   107521 tttgtatggt ggatagtctt caccttcgat aagtggttgt aaatattcac gacaagcctc
   107581 agtaatacca aagccgtcgt tagaaatata gttcataagc atcatctttt caatgttggc
   107641 aatatctttt aatttgcctg aaccaatttt ccaagtataa ggattatttg atgttctaat
   107701 aatagtaggc atgactgagt ttttaccttc aagtgccatg ttaatagctg cctgacctaa
   107761 tgcatatgct tgtttaacat cggattttga ggctaagtga cgagcagcac gttgcaagta
   107821 atctgcaact gcccagtggt acttataacc taaggcattt ttaattaatt tagcaataat
   107881 aggtgctacg ccaccaagct gagcatgacc aaaatcatcg tgtgtatttt gctctgatag
   107941 gaaacgacca tctggccatt ttgcaccttc tgatacaaca attgtgcagt agccaaattc
   108001 tttgacattt ttatcaactt tagctaagaa ttttttttca tcaaaaccaa cttctgggaa
   108061 taaaatcacg acagggatag agtcatcaac taaaccacct gctgatgcaa tccaacctgc
   108121 atgacgaccc ataacttcaa ggacaaatat tttagttgaa gttgctgcca ttgaagcaac
   108181 gtcaaaacta gcttccatag tagaaacagc aatatattta gctactgatc caaaacctgg
   108241 agaattgtct gtaattggta agtcgttatc gactgttttg ggtatgtgaa tagcttgaat
   108301 tgggtagccc attgattcag ataattgaga aacttttaaa caagtatctg ctgaatcgcc
   108361 accaccgttg taaaaaaaat agccaatatt atgtgcttta aaaacttcga ttagtctttc
   108421 gtattctgct ttgtttgttt ctaaagattt cattttataa cgacaagagc cgaagccacc
   108481 agaaggtgtg tgttttaagg ctttaatatc ggcactagat tcttttgaag tatctattaa
   108541 attttcagtt aacgcaccga taataccgtt tttacctgca taaactgtac cgattgtatt
   108601 tgaatgttta cgcgctgttt caattacacc acaagctgat gcattaatta cagcagtcac
   108661 cccccctgat tgtgcataaa aagcattttt cattattttt ccttaatttc ttaaattcaa
   108721 taattatacc tttaaattaa aaattttaat tgaaaacata aggagtaatt ttccattttt
   108781 ggaattggtt aattttaaga atgaagcatt ttgaaccacc ataattacgt attttcccag
   108841 cagcgccagg gttgataatc caaggtgttt ttatcttatc tatgacttgt ttatgagtat
   108901 gtccataaat gataattttt gaattaggat aggcggctct taacgagtta tgagaaggtt
   108961 gatgatgtcc atgtttatgt ccatgttcga tgatgatgtt tccacttgaa aaacttaatt
   109021 tttctattaa atttagatga gttatgtgtg tgtcattatt gccttgtatg gcaattaatt
   109081 tttgtttagg tatgagtgct tgaagggttt tttcatcaat aatatcacca gcatgaataa
   109141 taatatcgca ttggttcatt aacttaacaa tgttgggatg aataaatcca tgtgtatctg
   109201 agagaatgcc aattgatgta ttcatcatat gttaatattc cttgataggg ttaaaacttg
   109261 ttcaaaattt ttgatattag taaactcttt tattgatttt atatttattc gagagttgaa
   109321 tttattaatg gtaatgatgg tgctaatgtt atattgttta gaggaattta tcacagataa
   109381 agagttatca aaaaaaagat atttttgttt gttaagctta tttgagtttt ctaatttgtg
   109441 ccaaaatcat tgttcttttt ttacattgta gtcatacgat gaaataattg catcaaaaga
   109501 ttgtatcaaa tgagtcgttt gtgttttcaa ttaaatgatg ttcctataaa tgttagtaac
   109561 taaataaata cactttcttg ttcctttttg tttctttatg ctttatgtta catagtctat
   109621 cataaaagga tgtatttgaa tcatacgaac tatatccttt tttggtttgg taatgtccac
   109681 tttaaatatt tcttttatca ataattcaaa caatacgaat gtgactttct ttattctttg
   109741 caaagaatga gatagattat ttcatttata ttttgatttt tggtgtatta ggttgtggtt
   109801 tattatcaaa tactaataga gtatgtcata ttttccattg aaaaattcaa gtttagcaaa
   109861 gtactgttta tttttaataa aattaaatat agtgtctatt gaagatcatt taatactatt
   109921 tcttacgcca agttgtacca ttgatattgt cctctagtat aatatcaaat ttagctagct
   109981 catctctgat gtaatcactt agtgtaaaat ctttattgat tctggcttta tttctattgg
   110041 tgatttttat attaatttgt tcatcagata aagaaatacc ttgttttaaa aatttatctg
   110101 cattcatctg taaaatacca atgtaaccac cgagtttttt taataattgt gccaaggtct
   110161 tggcctggtc agtgttattt tcacgttgta tattgactat ttttgccaat tcaaataaaa
   110221 cacttaaagc aataggtgtg ttaaagtcat cgtcaagtgc ttcattaaat cgaactgaat
   110281 aatcaaaatg tatagatatt tcctcagttc ttacgttaga agtatttaag ccgcgaatag
   110341 tggtgtataa gcgagacagt gatgattttg ctttattaag attctcatct gagaagttga
   110401 gcggactgtg gtaatgagaa ctcatgatga aataacgtaa gatttcgcca ttatagtttt
   110461 ttagtacatt acggattgta aaaaaattat tcagcgattt gctcattttc ttattattaa
   110521 tatttacaaa accaacgtgc atccagatat tcacaaaagt gcaattattt gcaccttcag
   110581 attgggcaat ttcgttttca tgatggggga aggttaaatc cattccacca ccatgaatat
   110641 caaaatgatt acccaagtga tgtgtggaca tagcagagca ttcaatatgc caaccaggtc
   110701 gaccctttcc ccaaggagat gaccaacttg gttcgttagg tttggacatt ttccatagaa
   110761 caaaatctag agggtctttt ttggcacttt ccaccttaat tctagcgcct atttcaagtt
   110821 tattaaggtt tttccttgag aattttccat aatttttaaa atgtcgtact gaataataaa
   110881 catcaccatt atgagcttga taggcaaaac ctttctcaat tagcgactta atcatacaaa
   110941 atatttgttc cattgtattg gttgcacgtg gttcaacatc aggtggtaat attccaagtg
   111001 catgttcatc ctcgtgcatg gcgttaataa agcgattggt caatgtgtat atatcttctt
   111061 tattttcaac ggcgcgcttg ataattttgt catcaatatc ggtaatattg cgaacatatt
   111121 caacatttga gaaatgtcgt ctaagatggc gggtgatgac atcaaacatc accaatactc
   111181 gtgcatgacc catatgacaa taatcataaa ctgtcatccc gcaaacatag atacctactt
   111241 tattattatt aattgggtga aaaatctctt tttgtttact tagagtattg taaattttaa
   111301 gcataagtag tattttacgt aagtatttat ccagttttgt cttgtcaata aaatataaac
   111361 ccttactttc taaattatga tttattagta taagtaactg tataattaac taataattat
   111421 ttaaattata tataggataa atatatgaat gttttagtaa cacaacaagc tccagatttt
   111481 aaagctgctg ctgttttagc agatggtacc attgttaata actttcaact ttctgacttt
   111541 aaaggtaaga aaattgtatt gtttttttat ccattagatt ttacttttgt ttgtccttca
   111601 gaaattttag cgcatcatca tagaatgatg cagtttaatg agaaaggtgt taaagtggtt
   111661 ggtgtttcag tagattcaca atttacgcat aatgcatggc gtaagatcga tccaatggat
   111721 ggtgggttgg gtgttattga ctttccattg gtagctgata ctaatcattc tattatgaag
   111781 tcttatggta ttgtgcatcc aacaggtgtt gcattgcgtg cgtcgttttt aattgatgag
   111841 agttttgata ttcgtcatca agtagtgaat gatttacctc taggacgtaa tgttgatgaa
   111901 atattacgta tggttgatgc acttgatttt catagtaagc atggcgaagt ttgccccgca
   111961 ggttggaatg atggtgatga aggtatgaaa gatacacctg caggcgtagc taattatttg
   112021 tcacaatatg ctgataaatt ataagtgaat aagtttcatt ttcttataat cttatacagg
   112081 gagaattggt aatggtaatg aagaagtata gatgtattgt gtgcggttgg gtatatgatg
   112141 aatatttaag tacatctaaa gaaggggctg agttaggcca aaaatgggaa aatatccctg
   112201 aggattgggt gtgtccggat tgtggtgcta gcaaatctga gtttgaaatt gttaagatct
   112261 agttaaatac tatttaaaga ttaaatataa aggaagaatg tcaaaagtat taatattgcc
   112321 aggtgatggt attggtcaag aagttgtaat acaggcactt aaagtgattg actttctgaa
   112381 tgcaaatttt aatcttggta tgacgcttga acatggttta attggtggta gtgcttatga
   112441 tgtaactggc tctcctttgc cacaagacac attggatgtt gcacgtaaat gtgattctat
   112501 tttattaggt gctgtgggtg gttataagtg ggagtcttta ttacgtgatt tgcggccaga
   112561 gcgaggttta ttaagactac gtgcagaaat ggatttgttt tctaatttac gtcctgcaat
   112621 tctatattca caacttatta gtgcttctac attaaaaaaa gaagtggtat taggacttga
   112681 tttgatgatt attcgtgagt tggtttctgg tatttatttt ggcaaaccgc gaggtataga
   112741 gatacgtaat gggcaaagat atggttttaa cacagctact tattttgagt cagaaatcag
   112801 gcgtattggc cattcagctt ttaaaattgc acaactccgt aataagcgtg tttgttctgt
   112861 agataaagca aacgtgttag aggtatgtga attatggcgt aaggttatga tagatctggc
   112921 taaagattac ccagatgttg agctatcaca tatgtatgta gataatgttg caatgcaatt
   112981 agttagagca cctaagcaat ttgatgtaat agttacctcg aatctatttg gtgatgtatt
   113041 gagtgattgt gcagcaatgt tgactggttc aattggtatg ttaccgtcag cttcacttaa
   113101 tcaatatgga tttggtatgt atgaacctat tcatggttca gcacctgata ttgaaggcaa
   113161 agacattgct aatcctttgg cggctatttt atcggttgct atgatgttgc gttattcact
   113221 taatcaagcg catttagcgt ttaaaattga agcggcagtt aatgctgtat tagataaagg
   113281 ttatcgcacg ctggatattt taacagaagg tggcatggtt gttggtacta atgaaatggg
   113341 taatttggtg gtagaggcat tagtatgaag attttagttt ttgaatccaa atgttttaga
   113401 gtttaggcta ttatctgttg tattatcgaa tagtaagata ttatttagct atatagtttt
   113461 atataaattt ttatattatt ttatgtgagt ttatataagg cttaattaga taattaattt
   113521 cattttttta aactcttgtt tgatttttac taacagggaa gaattaagtt taaattcatt
   113581 aaaatatata ttctataaat catactattt ctcgttagtt ttattctttc ttttataaac
   113641 taaatatatt atagttgaac tttattttgt taaagaactg gattcaatac agatataatt
   113701 tgtatagtac tctaatatat tatttataaa tctgatggtt ttgttgtata aggttaggta
   113761 ttttatatat ataattattt agtattaact tttgattttt taatgctcat tatatcgtca
   113821 attcattatt acttaattct aatatttaat atttgtatgt taacgttaat tcaatagaca
   113881 acctcttttc tttgacacaa tttattaagt tttgtggtgc gactttttgg gtttttattc
   113941 aagttttgtt aatatctaac aggattattt ttattctatt attaccaatc tatagcacga
   114001 ttaaaaaaga attttaatag tataactgtt tgtatttaac ccatgaagaa tatacaaaat
   114061 ttaattagaa ttaaattcta ttatagatat actatattaa ggcttgtgta tgatctataa
   114121 actacgctaa aatttagtaa cgaataagaa ggttcaatta tgcaaccaat gcttgctaga
   114181 tttgtgttaa gattaaggag ttattaaata aatgagatct attatttgag taaaatatta
   114241 tttggtgaag gtcatgtgct tatagtatgc ttattaaaaa taacggcgtt aatatagtaa
   114301 taaaaattgt tatcaatata tcaataattg attaatctaa ctaagtttca taaataataa
   114361 ctttatctat cttgttatat aagttttata actctagcgc ttcaacttca agtagtactt
   114421 tactaatgtg attaccaagt tggccataaa atccatgcca atttttatag gaatttaatt
   114481 ttttaatggc gataggttta atttcatagt cagtaaaatc tttttcataa ccttttttag
   114541 cttcagattg aataattagc aggtaatcta aaaatggctt aacagtatgg tttacattgc
   114601 ctgatgagcc atgtccaggc acgtaataat ttagacctaa gtttgttgca tattgcaata
   114661 ctttgatgtt gtcatgtatg ctagagctat tgtcaaaagg acccatacga ttaacaaaac
   114721 tgttatctcc taagaataaa gttttactgt taatatgttc aatcataata tctgtattag
   114781 tatgtgattt gatggtaggg ttgtgaattt taaattgttc tgagtctaat ttgattactt
   114841 gtaaatgttt gattggattg gttgggtaag tggcaatcgt gtcttttgtt aaaccgttag
   114901 tcagtgttgt cattatatta atccatttat tgccttttcc atttttagct tcaataatca
   114961 tttgtggatg ggcataaatc ttagtattgg gatatttttc gataattgca tgattgccta
   115021 accagtggtc accatgaata tgcgtattaa agacagaaat aataggtttt ttggtaattt
   115081 tttcaacttc tttaatcact tttttaccaa tatcataact actacctggg tcaataataa
   115141 taacaccttc ttttccaata ataatgccag gattgtttat aaatccttgg ttttgaatat
   115201 tcggtttccc aaatggacca tgaatgacaa atagattatt gctaattttt tcaggtgaga
   115261 attcacctat tccttcaatt ttccaggcgt ttgataaggt tgatagagtt aaagtaaata
   115321 aaagatagat tgttttcaac atttcctcca ataaaagttg ttgtatctta tcagatttat
   115381 aggtataata ccttaaacag atttgttctt ttttattgtt taaagttaaa tatataacag
   115441 ttaaaaggag tttaattgtg ttgatataaa aagtcatact tggaaataaa tcatttttta
   115501 attaatacaa gttttattgt agatcttttg atgagtgtta cgagagtggt tattcctagt
   115561 ttagtagata cagaatttca ttcaggtaag taataatgct tattgttaac ttcctttgtt
   115621 gtatttagtg tgattttata tatgctgtaa tggcatgaat aatagcgtta atttttatta
   115681 gcatatactg atatgattgt atctaaacta tacgctttaa tgatgatgct aaattgtaag
   115741 atttatgttt agcattaatc aatggcatta atcaatggca ttaatctaac tatgcgcaag
   115801 aaaccaacgg tactaaatat taaaactatt gctacaacta atttcttcaa tattgaagaa
   115861 atggatatta agttctcaaa tggtgaaaaa agaatatatg aacgtctaaa gccatttgaa
   115921 aatggtgcag tattaattgt tcctatgtta gatgatgaaa ctgtgcttat gatttatgaa
   115981 tattctggtg gtacagataa atatgagctt gtattaacta agggaaaaat tgatgataat
   116041 gaaatacttg ttgaggccgc taatagagag ttaattgaag aaattggttt tggcgctaat
   116101 aaattaacct ttattaaaaa aatgaccatt gcacctagtt atcaatctag tattacttat
   116161 attgtattag cacaagattt atataaagca aaggcacaag gtgatgagcc agaattatta
   116221 gaggtggtta catttaggat ggctgatttg gaaaacttag tttacaacga acacttaact
   116281 gaggctagaa gtattgcagc tttatatatg gcgagagata tgattaataa ccaataatat
   116341 aatagttata gttgttgaaa tatctaagaa ttttttgtca tttcatgacg ttaaaagcct
   116401 gatgggtttg attgtattaa gtgttaatta aaggcttatc aacgaggaat tttattttga
   116461 tctataggat taaggccagt gtattagtat tttctagatt taagagtaat gactatttta
   116521 gagtgacttt ttattttaaa cagtttaaat aaaatgattc agcgtaaaaa ttaaaatggt
   116581 acttggattc ataattatat ggcgcgtgtt tatagcgaac ttcataagca aggatttacg
   116641 tacttagttg gtgtgtgtta agattttaaa ttgtcaggca agttttatag tattgttcta
   116701 agttaagtat tttttattaa ttttgatacg taatgcttat aagtctgttt ttgtatatct
   116761 gttcatgaat atattttata aatttggttg attgttaagt cgagaacttg catttaaaaa
   116821 acttggttat tttaatatac agtgttatgt gttaacgcag ttattaataa aattattgta
   116881 aaatggcctg tgttttaaat aaaaaaaaca ggcaaggaag taatatgaaa aagataacca
   116941 tacttatagt attagccttt attgttatta ttattactgc ttgtggaaag atgggtgaat
   117001 tggaacgtgt taaatcatca tcatcatcat taggtatatc aagcattacc caaattatat
   117061 aatgggtttt tcttatcaaa atcacatact acatgctgag tctgttgcta tagcagattt
   117121 gatgaaaacc tatggatcac ctctttatgt ctattcaagg acagatattg agtataattg
   117181 gcatttgttt agtcatgctt ttggtattca tccacattta gtttgttatg cggttaaagc
   117241 caactctaat ctagcagtgc tcagtgtatt agcaaaaata ggttctggat ttgacgttgt
   117301 atctaatggc gaattagaac gtattttact tgctggagcg gatgcatctc gttgtgtttt
   117361 ttcaggtgtt gctaaaacaa atattgagat taaacgtgct ttagaagttg gtattttttg
   117421 ttttaatgtt gaatctatgg cggagatgat tcgtattgaa caagtagcaa aagaaatgag
   117481 tatgcaagca ccaatttcat tacgagttaa tcctgatgtc gatgcaaaaa cacatccgta
   117541 tatttcaaca ggacttaagg agaataaatt tggcgttgat atcgatgatg ctattcctat
   117601 ctataaaatg gcatataact ccccctattt aaaggttaaa ggaatagatt gtcatattgg
   117661 ttcacaatta acgaaaatat ctcctttttt agatgcgctg gataaagtgc ttgaactagt
   117721 tgctaaactt ggtaagctta atattcatgt tactcatttg gatttaggcg gaggtgttgg
   117781 tattaagtat gacaatgaac aaacaattga tattaatgct tatatttctt ccattcttga
   117841 taaagtaggt agtttaaaaa ttattttaga accaggtagg gcaattgtcg gtaatgctgg
   117901 tatatttgtt accaaagttg aatttttaaa acagaattca gataagtcat ttgcgattat
   117961 tgatggtgca atgaatgact tattacgccc ttctttttat caagcttatc atcaagtatt
   118021 gcctattgat gagaatgctg aaggtattga tgctcattgg gatttagtgg gaccaatttg
   118081 tgaaacaggt gattttttag ctaaaaatag aagactttct ttatcggaag gggactattt
   118141 agcactgatg tctgctggtg cttatggttc taccatgagt tcaaattata attcccgtcc
   118201 tagggtagca gaagtgatgg tattaggtag tcaatacaca ttagtgcgag aacgtgaaac
   118261 tattcaggat ttgtttaata aagaatatat gattaatgac taaactaacc aataatcaaa
   118321 aaaagtttct tagatcaaaa agccatagtt taaaacctat tgtgatggca ggacaacatg
   118381 gattaaatga gtctgtttta gcagaacttg agataactat ggataaacat gaattgttaa
   118441 aaattaagat acgtatggat aagagagcgg aaaagcaaaa aataattgat aaaattatta
   118501 atacttatca tgctcatttg gtgcaaatta ttggtaatat tgtggttatt tatcgtgcat
   118561 ttgatgaaga cccacaaatc atcctgccaa gaaaataaag ttcaatgagg attgcaatta
   118621 gtgcaacaga agcttcaggt gatttaattg gttctaaatt ggttgaatcc ttaagaaagc
   118681 aaaactccaa tatcatcatt gaaggattgg tcggggataa aatgtttgct gctgggtgta
   118741 tacagaattg ggatcaaaga caagtaaatg tgatgggttt tagtgaaatc ttaaagaagt
   118801 tacctttttt atttattttg cgtaaacgta ttattgctta tttttctagt caaaaacctg
   118861 atgtttttat tggtattgat gctccagatt ttaactttgt gattgagaga aaacttaaat
   118921 ctaaaggtat taaaactata cattttattt ctccttcggt ttgggcttgg cgtcaatcac
   118981 gagttaaaaa aattaaacaa tcaacagatt tgatactttg tttatttcca tttgaagtag
   119041 atttttatca agcgtataat caaagagcgt tgtttattgg gcatcccttg gcacagagct
   119101 tgcatcctag aagatcacat attaagacaa aaaatattct cctaatgcca gggtctagac
   119161 aaagtgaaat caaacgattg ttacctgaga tgttgttggc agttgaaata atgtccttac
   119221 aagatagaat gttaaccttt aacttggttt tagtgaatga tgaattattg gattgggtaa
   119281 ctatccaagt agggaatatc ccagttgaaa tttcatttga tgatgcgcat acgcgtatgt
   119341 taagagcaga tttggcgtta gttgcgtcag gtactgcggc gttagagtta actttgattg
   119401 gtgtgcctat ggtagttatt tataaactat ctcgttttag ttattttatt gcttcaagat
   119461 tagttaaaag taaatatatc agtttgccaa atataattgt caataaaaat ctagtaccag
   119521 aattgataca aaatagtgct aatggtgata atattgccaa acatgccatg ataattatga
   119581 gtcgtgataa taaagcatta attcaagagt ttaatgcaat tcatcaacag ttagacttag
   119641 atgctagtga tgagtcagca cgtattattt atgagtttat caacgaataa gtacgttctc
   119701 aatagtgtgg tattagcttt agaagaagat cttggtactg gtgatgtttc tgctgattta
   119761 ttattagata aaataaatac agctgagatt atctcaagag aatcaggtat tatttgtggc
   119821 atagaatatg cacagagtac atttttattg cttaatgata atcttaaact agattggaaa
   119881 gttaaagatg gtgaggacat taatccaggg caggtcttat gtgttttaaa aggttcttct
   119941 aaggccatta ttagtgctga aagggtggca cttaattttt tacagatgtt aagttctgta
   120001 gcaacaagaa ctcattactt agtaaataaa attaatcata ctaatgcaca attactagat
   120061 actagaaaaa ccattattgg attaagattt gcacaaaaat atgctgtaaa atgtggtggt
   120121 ggtgttaacc atcgtatggg tttgtatgat tgtgttatac taaaagagaa ccatattatt
   120181 gcttcaggtt caattacttt gtcagttaaa atagcaatag aaaaatatcc aaatctacct
   120241 ttaattgttg aagttgagga cttaaatcaa ttacaagagg tgcttaagct tagtggtata
   120301 actagagcat tgtgtgataa ttttctcata agtgatttaa tacaagcagt tgttatggct
   120361 aaaggtaaat tacccttaga ggcttctggt aatatcaatg aaagtactat tgtagaagtg
   120421 gctaatactg gcattgattt tatttctata ggtagtatca ctaagaatat tcaagcaata
   120481 gatttatctt taaggtttat ttgaggcaaa gaaaatagga ctagttaaat catttttagt
   120541 attgtaactg agaggctttt cattctgatt aacaacactg cctccggcat tttgtagaat
   120601 acatacgcca gcagcagtat cccattcaga acaagggcca aattttgggt aatagtcata
   120661 tttaccttct gcaatagcac aaaattttag cgcactaccc aattgtgata acttatatgt
   120721 gctgtatttt tttaaatggt cttttaattg tttattgtgt gatgaccaat gaccaatcac
   120781 aactcttaaa gggttgtgat taggacgtac atttaatggt tgaataatat tcttttgttg
   120841 tttgaatact ttgtttgcat ctgttgtata gtagtgtgtt tttcttggcg gtgcgtaaat
   120901 cataccaaat attggtttgt gtttttttat ataagcaata caaatacaaa actcatctgt
   120961 ttgcttgaga aaatcacgag taccgtcaag tgggtcaatt atccaatatt cacaccattt
   121021 agagcgctca gaaaattcaa ttatttcaga ttcctccgaa attataggtg tatttggcgt
   121081 aagttttgat agtgttttaa caatgagttt atgtgcgttt ttatcagcaa tggtaaatgg
   121141 tgttttgttt gatttgattt taatattaag ttcattctcg tatagtgaca taatcatatc
   121201 gccaactttc gtggtcattc taattagttt tggtatgagt aaatcaaaca tagctatatt
   121261 atcatatctc ataaagtatg ataagtgtta atggaaatgg taggtctact tggactttaa
   121321 tcaagaatta atagaagaaa atattaaaag tagagtaatt tgtgatattg gaaataaaaa
   121381 tattaaagtt tttcatcgtg tttggcataa ttatgataga gaatgtatct ttattgattc
   121441 gctaaattag aattataatc ttgtacaagt taaagttagt aacaataatt gaagtgttat
   121501 ttttgtaaaa attacagagt gattaaagat acacgaacct tgctgtatct aatcgaatat
   121561 tagctttaat agctttaata gctttaattt tatcataatt taagcagatt taaaataaag
   121621 taaaataaat aacaataaat tctttaatat ggtgggccta cttggacttg aaccaaggac
   121681 caatcgatta tgagtcgatt gctctaacca actgagctat aggccctaaa gaattattct
   121741 aaaaagcttt gtaatttatg cgcacgagaa gggtgtctta acttgcgtag tgctttagcc
   121801 tcaatctgac gaatacgctc acgagtgaca tcaaattgac gaccaacttc ttctaaagta
   121861 tgatcagtgt tcatgttaat accaaaacgc atctttaata ctttggcttc acgaggtgac
   121921 aagttagaaa gtaaatcacc tgtagtttct cttaagcttt ctttggtggt tatttcaacg
   121981 ggtgaagata gattggtatc ttcaataaaa tcaccaatat tagaatcctc atcatcacca
   122041 actggagttt ccattgataa tggttctttg gcaattttta agattttaat aattttgtat
   122101 tctggtaatt ccatttcagt tgctagttct tcagaagaag cttctcgacc aaatttttgc
   122161 aagagttggc gacgtacacg gttaagttta ttaatggttt caatcatatg aactgggata
   122221 cgaatagtgc gtgcttggtc tgcaatagag cgagtaatag cttgacgaat ccaccaagta
   122281 gcataagtag aaaacttata accacgacga tattcaaatt tatcaactgc tttcattaag
   122341 ccaacattcc cttcttgtat taaatctagg aattgcaatc cacggttggc atatttttta
   122401 gcaattgaaa tcactagcct aagattagct tcaatcattt gagattttgc ttttttagca
   122461 cgacgatcac cacgacgata cattttgttt agttttttaa gttcaacaat agtgagttgc
   122521 atttcctctt cgaactgttg aaggtttttt tgagcatagt aaattttatc tttactatcc
   122581 tttagattct tctcaatttt ttcatctaat ttaacggtat caagccaatt gaaattagtt
   122641 tcattattag aaaataattc aaaaaaatgt aatcgattta ttcctgcgtc taagcagata
   122701 tttttaatga ttttttcttg ttctttgact tgacttacac gattacaaat aacttctatc
   122761 atagtattaa ctagtttagg agctagacgt aaatctgaca atcctttaga tagctgttga
   122821 cgtgttttaa ttgttttttt atggcgaaat ccaagttgtt cagtggtttt attgtaagtt
   122881 ttagagtatt ttagaactgt atcaaaacgg ttgtatactt gatttttatc tggtcctgtg
   122941 tattccattt cttctatttc ttcatattct tcatcgttat caaactcccc tgcatcaaag
   123001 gctactttct tattagcgaa atcttctgcg tcaccttgat aaccgataat tacatcggtc
   123061 attttacatt ttccttcttc taaacgggtg tgtgctttaa agaaaaaatc tgtaataact
   123121 ggatacaagg tgatactttg cataatttca aatacaccag cttcaatttc tttagcaata
   123181 cgaatttcgt cttcttgttc taataaatct acaacaccca tttcacgcat atacattcta
   123241 actggatctg ttgttcttcc aaactccgaa tcaagagctg ctagcgctgc tattgcagct
   123301 tctgctgaag ttgactgtgc tttggcgcca gattcaacca ctaaggtgtc tgcatctggc
   123361 actgtatcag aaacggtaat atccaattct tcaagaattg taacaatagg ctctacttgt
   123421 tcttgagtta ataagtcttc tggcaagatg tcattaattt cagagtaggt taagtagcct
   123481 ttttctttcc ctaccatgat gagtttttgt agtgcttgct tgtgtgcttt agttgtggat
   123541 ttcataaatt atgattatta tatttgaaaa gccaaatgat ggattatacc caaagttatt
   123601 agttagaaat catagccttg tattacgatg tttttattat actattatgt aaaaatagta
   123661 ctaatagatt gttcttcgct aattcgttta ataacttcag ccatcgttgg cgcaatggat
   123721 aattgtctaa ttttaaagca gttagcaaca tcaatattga gcggaatagt attagttgtt
   123781 attaattcat tcagttgaga attgttaata ttgttaattg cattaccaga aagtactgca
   123841 tgagtggcat aggctaccac ctctttggcg cctcgttgtt ttaaaatact ggcagcttgg
   123901 cagagtgtac cagcggtatc aaccatatca tcaattaaaa tacaacttct acccttaaca
   123961 tcgccaataa cattcattat cttaaccatg ttaggtgctg gtcggcgttt gtcaataatg
   124021 gcaagctctg catcatttaa gcgttttgca gcagagcgtg ccctgactac cccccctaca
   124081 tcaggagata caacaacaat atctttgtaa tttttagaca aaatatcttc aattagaacg
   124141 ggttgggcat aaatattgtc aattgggatg ttgaaaaatc cttgaatttg gtctgcatgt
   124201 agatcaacgg ttaatattcg gtcgacgcct gcagattcaa ttagttttgc tgcaagtttt
   124261 gctgtaattg gtacacgagt taagcgtgat ctacggtctt gtcttgaata accaaaatat
   124321 ggcacaacag cagtaattct tgtagctgat gagcgtttaa gtgcatcaac gataatcaaa
   124381 agctccatta gggtttcagc tggagaaggt ccgcaagtag gttgaatgat aaatacatca
   124441 caaccacgta cattttctaa tatttcaatt tggggctctc catcgctaaa tctacttaca
   124501 agtgctttac cttgtacaac atttaaacta gaaataattt ctctagaaag ttcaggatta
   124561 gcattaccgc taaagatttt aattttgtca agagacatag agggttaacc aatactatta
   124621 aagtggctaa attatacgct tataaaatat aaaatataaa aataagttgg ctgggctggc
   124681 aggatttgaa cctgcgtatg acgggatcaa aacccgttgc cttaccgctt ggcgacagcc
   124741 caattgtaaa tgggagaatt attgattgca cgtgttacaa aactcatcca tttttttggc
   124801 acttttttag ccgctgccaa ggcatctttt tcagttaaga attcattaaa aacacagctt
   124861 cctgttccac tcattctagc ttgtccgaca cgattatagc aagtatttag gtgttctagc
   124921 gcaacaccaa tttctgcttc taattttata gccacctgta aacaatcatt atgagtgttt
   124981 acaagctcag aaaagtttgc tattttccct tgaggttcgc ttattgtcaa tgcataatga
   125041 gaaaaaattt ctttagttga aatgtgtttg ttaataaaaa ctactagaaa gtaatgatcc
   125101 ggtgtcttaa tagggcttag aatatttcct ataccttctg cccaagcgct ttgagcaaaa
   125161 atgaatacag gtacatctgc acctaaattt aaacctaact tcataagttg tgcttgagtt
   125221 aattttgtat cccaaagttg attaagtgct actaacgtag ttgctgcatc tgaagaacca
   125281 ccacctaagc caccaccaat tggaatattt ttaacgattg agagattggc acctaatgtt
   125341 gttccagtat attgttgaag tgctttggct gctttaatga ttaaatcttg atcttgtttt
   125401 acgcttttat taccactagt acgtttaatg acaccattat tagttattgt acaagttaat
   125461 ttatcacaat aatccagtag ttggaagatg gtttgtaagt tgtggtaatt atctttcctt
   125521 cgtttgttaa tgtgcaaaaa taagttaatt tttgcaggtg caagccaagt actaggcatt
   125581 aatgaaaacg tttcggtagt gttttaattc atcaattgaa tcttggatat cagaaagggc
   125641 caggtgtgct gagtcttttt taaataccat tttttcatta ggtttccagt gcataattaa
   125701 ttctttaaga gtagaaacat caatatgtcg gtagtggaaa aattgttcta gtgttggcat
   125761 gtagttgtat aaaaaacgtc tatcttgaca aatagtatta ccacacatag gcgaggcacc
   125821 tttgtttaca tattttttta aaaattttaa ggtatgaatt tctgctttct tgcaagatac
   125881 attacttttt ctaacacgtt ttagaagtcc agaattagta tggtgttcag tattccactg
   125941 gttcatacta gttaaaattt tatcattctg atgaatggct agtgatgggc cttgtgcaat
   126001 aatatggagc tgcgcatcgg taacaatagt agcaatttca ataataacat ctttttcagg
   126061 cgtaagacct gtcatttcta aatcaatcca aattaagtta gtatctttat ttatcataaa
   126121 aatctataat taacagccag ttgattcacg gacaaaatca tctaattttt gatgggctac
   126181 cccactattt aagattttta acgctttact aacaccttct tgtagtgagt ttgcaagctc
   126241 acacacataa atagctgcgc ctgaattaag tgcaacaata tttttagcta cgctatcttt
   126301 gccatcaaga gcttgttgaa ttagtattaa tgagtcatcc gcattgttaa ctttaatatc
   126361 atctaaattg cctagtggta aaccaaaatt ggtaggatta atagtgtaag ttttaatttt
   126421 accattcttt aattcagcta caaatgtatc atctgcaatt gaaatctcat ctaacccatc
   126481 tttagaatgc acaactataa tatgtttaga acccaatttt tttaaaacat gagcaatagg
   126541 ttcaactaaa ttttgagtat agacacctat tatctgatta ggtactttag caggattagt
   126601 tagtggccct acaatattaa aaatggtttt aatagcaagg tctttacgca cattagtggt
   126661 atattttatt gaatggtgat gaaaaggtgc aaacataaat ccaatgccaa ttttttcaat
   126721 acatttgcta attctttcaa cactcatatt aagattaacg cctgctgcct ttaatacatc
   126781 agcactgcct gattttgaag aaatacccct attaccatgt ttggcaactg atccgccagc
   126841 agctgctaca acaaaggcac atgcggttga aatattaaac aatcctagtc catcaccacc
   126901 tgtaccacaa gtatctacta ggtgtttggt atttttaatg gtaacacttt tggtaaaaga
   126961 acgaatgatt ttgacaacag cagtaatttc atcaatactt tcacctttta ttgcaagtcc
   127021 aactaaaaaa ccactagttt gtgtatcggt agttttgccg gtcatgatat cgttcattac
   127081 tttttgcatc tcattctgac taagatcttg ttttttaaca atttgtttaa tagcttgttg
   127141 tatgttcata gtattatcgg ttcataagta attcaatatc gttgatctct ttagcaagag
   127201 atttagttag tactgtattt cctgatgttg ttactaatac aatgtcttca attctgacgc
   127261 caatgttgtg ataaattgga ttaattttat catttttacg tatataaata ccaggttcga
   127321 tagtggttat catgccagct acaaattttt tgtgatgacc attttttttg tattgaccta
   127381 catcatgtac atcaagacca agccagtgtc ctgtgctatg catataaaac tgcgataagt
   127441 cgtcatttat ttgcaatata ccaagatcaa ttaaaccttg tttgattgta ttagttgcaa
   127501 ctttatgagg tttattgatt tttataccag gtttgatggt attaatagca ttaatttgag
   127561 cattaagaac aatttgataa atttgttttt gtgtagaaga aaattgacca ttaactggta
   127621 aagttcgtgt gatatctgag gcgtagcagt caacttcagc accagcgtca atcaaaatta
   127681 aatcaccttt attgagtttt ttgttatttt ctatatagtg tagtaaacaa gagttcattc
   127741 ctcctgcaac aatgggagtg taggcatgct gagcattatt tttggtaaaa aaaccgtcaa
   127801 aaatactttg aacttcaaat tcaaacatat atggtttgat agtttgcatc gctaattggt
   127861 gtgctttgat tgagatattg gctgcttttt gcatggtgct tatttcaagt ttgtctttaa
   127921 taagacgcat ctcatgtaaa gttggggcga atgattttag tttatggttt aatagaaggt
   127981 ttttaatatt attatctact tgacaatttg tggtatcaaa gtacacttga ttattcaata
   128041 ttaattgagg tattttttct tttaacaaat ctatagaaaa agcattatct gattttaaaa
   128101 tattagatgc atcatcaatt cctaagcgtt gttcacccca gatttcacat gttttgtctt
   128161 taggacgtaa aaatattgtg tagttgtttt tagaaaaaat tgctagcgct ttaggctctt
   128221 gtaaaccagt tagatagtaa aaatcactat gcacccggaa tgggtaattg acatcaccag
   128281 aacgattctg ctcagaatta ctacttataa taacgactgc attgttatcc aactggttta
   128341 acagtgacag tcttcttttt tgatgtatca ttttatcaaa taaatcttaa ttattatcta
   128401 ctatttatta tatataataa tatcatgaaa catgtacgat tgtaccaaaa tatctcttta
   128461 aaaattaata agaaattggt acttgatgag tatgcatcat gtcatttggc aaaagcattg
   128521 cgatttttac aaggacaaga gattacttta tttaatggtg atggtaggaa ttatttagcg
   128581 acgattgtgc gagtcaaaaa ctattgtgag gttgaaatac atacgtgtac tcacaataat
   128641 tcagagtctc agttaaacat tactttggtt caaggtatta ccaaaggtga aaaaatggat
   128701 tttttaacgc aaaaatcggt tgaattagga gtgaatagaa taatacctat ttttagtgag
   128761 tattgcgtga ttcatctcca agatgagaaa ttacagaagc gcatggaacg ttggcaaaag
   128821 attattattg gtgcttgtga acaatcaggt agatctgtga taccaagttt ggtattagcc
   128881 atgaattttg aggattttgt taatactaag tttggtaatg ggtttatatt gcatcatcgt
   128941 gctaaatatt cattattaga aatgaataag gttaatcaag caactattat tattggacca
   129001 gaaggtggac taagtgacca agaaatagca aatgcaaatg aacaaggagc tcaaagtttg
   129061 gtattaggct cgagaatatt aagagctgaa actgcttcgt tagcaaccat tgctaatatg
   129121 cagttattat ggggtagtta atacatctaa ggctttttga ataggactta atatatttat
   129181 aagttttcta cgaatagcag aacctgttaa acggtgtgct gaaatggtgc taacgaccaa
   129241 acgttcactt acacctgcta atagcattct agcaaagagt ttttctcttt catctttaat
   129301 attacaaacc ataacattag cttggtttgt aatatcgaca atagattctt tgaaagttat
   129361 tgatggatga tatagatatt gtccgagtac atctagtgta cgatacaaaa tagtttcttg
   129421 attgattttt tttaaaatat taattgtggt ttttaatagt aattgtgttt gtttatttga
   129481 aataagttgt aagtcttggt gtttgaaatt aaatgatatt atgttaatat cagtatgaat
   129541 tttaaagtaa atatctttga gattcatacg ctcaataaaa ccaactaaaa atgctgtttt
   129601 cttttgacct tgttcccaca atttagcttt ttctgttttg ttgattaggc ctttttgtaa
   129661 tatcaaatta gtggtatcga ttagttgttc tatatcatgt ataaagggta ataattctag
   129721 taaatatttg gcgatatttc taccaatatt ggtgttaata acaaaatctt tagtgagtaa
   129781 caaacgcccg atttcagctt gattagcagt attagtagcg caccaccaag ttagtttgag
   129841 caaattttta tcaaatttga ttgcatttga tactgctata acagcttcaa cctcacccag
   129901 tttgagtagt aatgaaaggt ttgatgatgt cacttgtcct attcttgacc agtgttttaa
   129961 atatgataga tattttccct tcattgttcc cataacttga ttgataagaa gttctttaac
   130021 ttctttgata taggcatcac tatcacttgt taggcttaaa ttaatcattt gttctttaaa
   130081 ttgtgtgtta agtccaacaa ctattagttt ataagtatca atacgaattg cgattgaagt
   130141 cttaataaga acatttagtt taagaatgtc ttcagtgttt agcatttaga agtctattga
   130201 gtaacagaat ttattaaaga ataactagct cttgtttgct aatgtttatt attaaaaatc
   130261 tagattgata tgcatacgtt tgatggtagt tatttattat tttaactatg ttcttgatat
   130321 aatttatctt agatagtatt atttttatac ctatttttaa tagactaaat ttagtatgta
   130381 aattcaatac atacctcaaa agtaataatt aaatttaata aaaaaactgt ttaagtattg
   130441 aagtttgctg cttaatgact tattcatcat tgctcaattc tatacctatc ttatttgatt
   130501 tatcagaagc agcacgtatt gcatgagcaa taataatttc aaagtcttgg ttttgtaaag
   130561 actcaattgc tgcttgagtt gttccatttt ttgaggtgac tttattgcga agttgttgtg
   130621 gtgaatcttt agaacgactt gccatcatac ttgcacctag tgcagtttga atgcttaact
   130681 tttgtgccac tacttcatcc aggcctaatg ttacaccagc tttagtcatt gattcaagca
   130741 ttaagaaaaa atacgcaggg ccactaccag aaactgccgt gattgcattc aacaagtact
   130801 catcatttac ccataagcat tcacctacag aatttagtat gttttctgct agaaattttt
   130861 gtttgtttga tacttgtttg ttagcaaata aacctgttat tccttggttg agcaatgcag
   130921 gtgtattagg catggtacgt ataatagctt ggttaccacc tagccagcgt tcaatatcat
   130981 gtgatcttac ccccgcagca atggatataa taagtgtatt ggttgtaagc ttgtttttta
   131041 aatttttaca gaccgaggat aatacttgtg gtttaacagc aaaaataata gtgctacatt
   131101 gagttgcaag tttggtatta tccgtaaaaa tttcaatatt aaattcggtt tttcgaagaa
   131161 gtaataatgc ttcgttagta tcactgattt tgatttggtt atggttagtg ttattgttaa
   131221 taagcccaga aataatagca tgggtcatat taccagcgcc gataaaaccg ataagtgagt
   131281 tttgcataac gaatattata aagtattaat atactgtgta ttttaccaaa atagtatttg
   131341 tttaaaaaat aaaaggacgt caatgaaaac atttaatcca aaattaatta tgattgattt
   131401 agatgggacc ttggtggata gtgttccaga tttagcctat tgtattgatg aattaatgaa
   131461 agcaatgaat aggacgccat ggggtgagtt taaagttcgt gattgggttg ggaatggtgt
   131521 actaaaatta gtagaaaggt cattaactgg tgaacttgag gcaagtgtta ataaacaaga
   131581 ttttgacaaa gcttattcaa tttttttgga attgtatagc attaacactt ccgtgcgttc
   131641 atgtttatat gacggtgtaa aagaaggttt ggattatcta aaacgacaag gttatttgtt
   131701 aggctgtgtg acgaataaag acgagcaatt taccttgcca attttaaaag atttggatat
   131761 ttttaattat tttggattgg taatttcggg tgatacttta gtaaagaaaa aaccagatcc
   131821 attgccatta ttacacagcg ctgaattttt taatattcct ccacaagatt gcttaatgct
   131881 tggtgattca attagtgatg taattgcttc acgtgttgct ggttttgaga ttatttgtat
   131941 gtcgtatgga tataatcatg gtaaggatat ccaagatgtc aatccagatt tagttattga
   132001 ttcaatgatt gaacttaaag attatttata acagctagta tcagtaaaat atattcatat
   132061 ggatacattt gacaaccaac atatttggca tccatatgcc aaaattccta acgaagttcc
   132121 tacttatttg gttgaatcag ccgagggtgt ttatttaatt ctagaaggtg gtaaccgcgt
   132181 tattgatggt atgagttcat ggtggtcagc aattcatggt tataatcatc cagtacttaa
   132241 taaagcgatt gaaactcaac tcaggaaaat gtcccatatt atgtttggtg ggttgacaca
   132301 ccaacctgca attgacctta ctaaaacatt attgagcgtt acacctgata atttaaccaa
   132361 ggtatttttc actgattctg gttcactgtc agtagaagtt gcacttaaaa tggtcctaca
   132421 atattggaat aataaacacc aagctaataa gcaaaagttt attactatcc ggggaggata
   132481 tcatggcgat acatttgggg ccatgagtgt gtgtgatcca gataatggta tgcatcattt
   132541 attttcaagt gtattaccac aacacttttt tgttaaaagt ccatctattg tgcctatgaa
   132601 tgaggctctg gaagatttaa gagtgacatt aaaacaaaat tctaataaaa ttgctgctat
   132661 gattttagaa cctgttatac aaaatgcagg aggtattcgg acatacaacc ctcagtattt
   132721 gcttaaagct aaaaagcttt gcaaacaaaa taatatttta ttcgttttag atgaaattgc
   132781 aaccggtttt ggccgtactg gagaattatt tgcacttgaa tacgctaatg ttgaacctga
   132841 tattttatgt ttaggtaaag cattaacagg cggttatata actttagcag ctacattaac
   132901 aaccgatgat gtttcaaatg tagtaggcac acttatgcat ggtcctactt ttatggctaa
   132961 tcctttagct tgtgctgtcg ctaatgctag tattgaatta ttacttagtt ctccttggaa
   133021 aaatagtatt gccaatatcg gaaagatatt gagtgcagaa ttattacctc ttaaaaatca
   133081 tgataaagtt aaagatgtac gaatcttagg tgctattggt gtaatagaga ttactcatga
   133141 aattgatata caaatagtcc aaaagtattt gattgatttg ggtgtttggc taagacctta
   133201 tggaaaatta ctttacacca tgccaccatt tataattact gatgatgaac ttttaacaat
   133261 tactagtgct attaaagcta tagttagtag actttaacct taatacaata gacagtcaga
   133321 tggaatagtc tattactgtc tattatcatt gtttgtttta gacggtttta atttagaaac
   133381 agttttataa gttattttca ataaaaagat caattttata tctagattca tttagtaact
   133441 taaaatgggt agtgtagaaa ttatcgaaaa gacgtctact aggtgtaagt tttttggatt
   133501 agtatttgta tctttgtaca tcttttattt tttaagtaat gataaagatg tggtgagtag
   133561 tagatagcta agagtaataa ttagtttatc tattctgagt tttgtctcgt attttataat
   133621 ttagtagatt tactttatta gtcattaact aatatgcgta tgacataatt ttttatagtt
   133681 tcatatcttg gtttttgttt tcttttttca aatttttata tgcttcttgt tcttattttt
   133741 aataaatttg ctattttagt ttgtgaatca cattttattt taaaactaaa ttaaatcaaa
   133801 aatatgcctg ttttttagta tattagaaga atacttatcc aagaattata taaggatgat
   133861 tgttagatac tatgtttgat atatttattt attatgacaa tatttataga aaatgaaata
   133921 tcatctgtaa aatataccaa tatgattaga gcttctaaca aatgtgttaa atactagtat
   133981 ctacaagatt ttctaacttg tagaaagata gataataatg acagataaat attagattag
   134041 tctaaaaatt ttaatttaag ttattaatat ataaatatat ttatagtatg ttgattataa
   134101 caacttattt tttattttac ttaagagtta taaacttact tacataataa aatgcttttg
   134161 aaattgataa ctcaatgagt aataacttta tttgctgtta ttcaattgga tcaatatcta
   134221 aataccaacg tactttgttt ttaagtttga gtttattgat gtgttgactg aaagtggata
   134281 atatttggtg gagtgttact cgattgttag attgtaggta taggttaaag tagtagtagt
   134341 ctgacttttt ttcaatagta ttagcaattg gcccccaaat ttctactgaa ttcatttgta
   134401 tgctttttaa caaaatggct gcttcatgta agaaattttc agcgttttgt ttgttttttg
   134461 cattagcaca taataatgct tggtgtgaaa aaggtggcat cattgcgctt aaacgctgtt
   134521 ttagaagttg actagcaaat tgtgtatagc gagatgacaa aacaaaatta aaaattggat
   134581 gatcgggata gcgagtttgt ataacaactt cacctctttc tttgtgtcta ccagcacgac
   134641 cagatacttg aataaggagt tgtgctaaat attcagttgc tcgaaaattt gttgacaaga
   134701 atccagtatc aacatctaga ataccgacca ttgcaaggtt ggaaaaatcg tgtcctttgg
   134761 ttaacatttg tgtaccaata ataatacaag gtttaccagt attgatttgt tctaagtgtt
   134821 gtgcaaagga tttcttacgt cttgttgtgt cacgatcaat gcggataata ggagtgtcta
   134881 caaagtatga atataaggtt tcttctaatt tttctgtgcc atatcctaat attttaaggc
   134941 tttgtttagt acaatttggg cagacgtgtt ctggtatttt ttcgtcgcca caatgatggc
   135001 atttaagacg attgatatgg cggtgataaa ccatggttga atcacaatga ttacattgtg
   135061 ctttccagtt acattgtgta cagtaataga taggtgcata acctcggcgg ttgataaaca
   135121 acataacttg tttatcaatg gataaatatt gcttgatttt ttcaattagt attttagata
   135181 atgcgtcatt agtattactg cgcatatcaa tcagacttac cttgggtaaa gttgcaccac
   135241 ctgcgcgttt agttagtgtg atacgtgtga tttttttatc cattgctatt tttaataact
   135301 ctaacgaagg cgttgctgta cctaatacca atgggatatt agattgttga gcgcggataa
   135361 aacctaaatt tctagcagag tatcgaaaac ttgattgctg cttaaacgag ttatcatgct
   135421 cctcgtcaat aataattaaa ccaaaatttg atataggtgc gaaaatagca cttcttgtac
   135481 cgagtatcac gccagcatca ccgtttttag ccataagata ggcatctagt ttttgagtct
   135541 cgttaagttg cgaatggatt gctattacgc gtgtttttag gcgtgattta aaatgtgtaa
   135601 tcatttgtgg tgttagacca atttccggaa ccaatactaa tacttgtttt ttttggtcaa
   135661 tcattgattg gatgatgtgt aaatatactt cagttttgcc gctaccagtc accccatgta
   135721 gtaaaaaagc atgatattga ttggttgatt tcaaaatttg ttcgatagca atattttgtt
   135781 catctgttgg ttgaaagtct ggttgttgta gtttatttgg gaaatctatg atttttttaa
   135841 tttttgcttc tttacctaaa agtaagtttt taggtagtgt atatgaaata actttgctaa
   135901 ttggataatg gtaataatta gccgaccaga acaagaggtc taaaattgat ttgtctaaaa
   135961 ttggtatttt atctagtact ttttcaacag atttaagttt ataccctagt gtatcttctc
   136021 ttttttttcg gaaatttgtt tcgttatatc tacttttatc tttaatggct aatacaatgc
   136081 caattacttt ttttcgtgca aggggtactt taacacgtac gccaacagac acttcgttat
   136141 cacataggta gttaaaggtt ttgcttaatg gtatagatat agcaacttca ataattaatg
   136201 acaaagtaat agagtattga taaaataaat attttatcaa taaatatcat tcaatctaat
   136261 attaagtatg gtgattatac aaaataatat tcacgattta tctgttaatg aagatgattt
   136321 aagttgtatt ttacaaaaag tggttaaaga gtggggaaag ggtgaaagtg agttgttagt
   136381 tcgattggtt gatgaagcgg agattcaaaa tcttaataaa gtttatcgat acaaggacga
   136441 acctaccaat gtattatcat ttccaactga tttgccgatt gaaattgatg aaaagatttt
   136501 aggagatgtt gtgatctgta tacaaatagt tttaaaagag tctattgaac agcataaatc
   136561 ttttaataat cacttaatgc atatggcagt tcatggtacg ttacatttat taggttatga
   136621 tcatattgat actaaagatg cacaaaatat ggcaaactta gaaagaaaaa ttctagcaaa
   136681 aattgggatt aataatcctt attaaattag caaaaaatgc cactacttat ttaaaattgg
   136741 aaatgcttgt tttttatatt aagcgctata ggtcttacca atacgctcaa tggcatataa
   136801 tttattacta atgtaataca tttttaactg gttccgttcc caaggtggaa tattagcttc
   136861 ttgtaatact ttttttaatg atttggtgtg ttttttttct agtaatttaa tacgttgacc
   136921 tttttgtcga taacgaattg aaaaatttgg gaagtcctta agttcttcat gaaatgggca
   136981 aggctcgttc ttctttagca gggttttgtt gatgaaatat aattcatttt tgtagcgtct
   137041 aacctcgtac ttattccaac aaactagtgg tttagtgtcc ttttttgcgt gcagtagttt
   137101 aataatttgg tgcattattt tatcgctggg tgttaaaaaa ttaagcaagt ttagatgatg
   137161 gcggataatg ttcttaattc tatggattcc aagtttaata agctgactta tattgatgcg
   137221 attagtatga ttgataatat aatatgtttt aatatcaata tcggccagtt cacgtgtaag
   137281 ttttaaggtt tctgattggt gttgtgcact tctagcaagt gtttctgtta aatttttata
   137341 tacttcagat aattttggta gaatttctaa acgcaagaaa ttacgcctaa aataagtatt
   137401 cttgttgctg tcatcttcta tccagtttaa tttgtgatta ttagcataat cactaacttg
   137461 agatttatta attgttaaaa aaggacgata gtgaatacct tttcctagag gtttttcttt
   137521 aggcatagca gctaatccag cactaccact accacggaat agttgtagaa gtaatgtttc
   137581 tgcttggtcg tttttatggt gtgccgtgca tagtacttca ttttctttta acaagttaga
   137641 taatgaatga tatcgttttt tacgtgcatt ttcttcgata ttagatgtat tgtcaaaaga
   137701 taaattaatg cttaagtaaa caatattaag attcaaacat gttgttttgc aaaatttatc
   137761 ccatttgtta caaaattgag ataaatgatg attacagtga ataactctta ttttattggg
   137821 atagtgcgtg tttaaataat gcaaaagtac gatagaatca atgccaccac tgagaccaag
   137881 gacaatgttc ttatcttcaa gaaataaatc tttagtcttt aaattttcca aagcctaaga
   137941 gttttttttg tctattttgc aataattgtt ctattggtag ttgtttaatt ttattgagtt
   138001 gttgtgttaa cacttctttt aaaagtacct ttgcttgtga agggttacgg tggataccgc
   138061 ctaatggctc attaataact acatcaatta acctttcttt tttaagatgg attgaggtta
   138121 attttaaaga ttctgctgca aggtttgctt tggttacgtc tttgtataag atagaggcac
   138181 aaccttctgg agaaattaca gaataaatac tgtattcaaa catcataatt atatctgcta
   138241 caccaatagc tagcgcaccg ccagatccac cttcgccaat aactattgaa ataataggtg
   138301 ttggaagggt tgacatttca aatagatttt tggcaattgc ttcgctttgt ccacgttctt
   138361 cagcgccaat accaggataa gcaccaggtg tatcaataaa agtaacaata ggcattgaaa
   138421 atttttcagc aagtttcatt aagcgtaagg cttttcggta accttcaggt ctaggcatgc
   138481 caaaattgta ttttattttt tcttgggtgg ttcgtccttt ttgttgacca ataaacatca
   138541 ctggttggtt atctaatgta gcaataccac caataatagc atggtcatca ccataagtac
   138601 gatcaccatg caattctgtg aattcatcaa atacatcaga aatataatca agtgtataaa
   138661 ggcgttttgg gtggcgtgct agttgagata tttgccaatc gcttaaagat gagaatattt
   138721 ttttggttaa agcattactc ttggatttaa gtgcttttat cttattaatg atatctgctt
   138781 tatctttaat atttgctttg cctttaatat tatcaagcgt ttgtattttt tcctctagtt
   138841 cggcaatagg ttgttcaaaa tcaagataat ctaagttcat actctagttt aaaatttgtt
   138901 gatatacaat ctttaaaatt atagcagaaa tactagcatt tctagctttt gctactttta
   138961 tattaagtta ttaagttatt aagttagttt tataaataaa cttagatagg tatttttata
   139021 atgttaaacg agtaagattt gatgtactat cattaataat gagtgaaatt aatgcattaa
   139081 ttcttattag tacattaaaa aaataaaagg caattaatat tgttttttga taaaaataag
   139141 gaagaaacat ggatgtaatt tattggcttg taccaagtat gatttttgtt ggtattgttc
   139201 ttgttattat tttaataata ggggttaaga atggtcagtt tgatgattta gaaggggaag
   139261 gacaacgtat tttatatgat gaagaacaga tgaatttagc acctataaaa aatattaaaa
   139321 ataaggttga caattcgtct ttttgataga aaattcgcat ctaaagatgc tagaagaaac
   139381 aaaatggctc aaaatataat agatggtcta tttggtaaat cacccattag ctcattgcag
   139441 aaacacatga cacaagtgca ttcttgtatt tcagaactta atggttttat gattgccatt
   139501 catacccaaa attgggtgaa agctgaaata attagaagtg atatagatac taaagaaggt
   139561 aaagcagaca tccttaaaaa gaatctacgt ttaagtttgt cttcaacgtt tatgatgcct
   139621 ttttcacgta gagatttact tgatttattg cttatccaag attctattgc caatatcact
   139681 aaggatgttt ctggtttgat gattaatcgt aagatgattt taccagatga gacttttgat
   139741 gatgttatag aattaactaa ggtttgtatc aaaacatcat ctacggcact taaggccgtt
   139801 aatgaattag atgaattatt agaaactgca tttggtagtc gtgagcgtaa gattattagt
   139861 tctattattg aagatattaa tgaacttgaa agtaaatctg ataaaattca gcacgaaatt
   139921 cgtgctgaat tatttccgct agaatctagc ttgccacctg ttgatattat gttttattat
   139981 cgtactgtgg aatggttggg tgagcttgca gatgcagctc aaaaagttgg ctcaagacta
   140041 gaagtgctgt tagcaagata agggaggcta ttatggatat aattgcaaat tatgctgata
   140101 tttttattat gctgtcaatt gggtttggtt tgtttatggc ttggggtatt ggtgctaatg
   140161 atgtttctaa tgctatgggt acttcggtgg gttctgctgc tattaccttt aaacaagcag
   140221 ttgttattgc ggttattttt gagttttctg gtgcaattct tgcaggcgga gaagtaactg
   140281 atactgttcg taaaggtatt ttagatgcag tattatttac taataatcca cacttactgg
   140341 tgtatggtat gcttgcttcg ctcttggcag caggtgcgtg gttattgatt gcctcatcct
   140401 taggatggcc agtttctacg acacattcaa ttgttggtgc tattgttggt tttggtgcag
   140461 taggtgttgg tattgatgca gttgcttggg ataaagtaat taaaattgtg atgagttggg
   140521 tagtatctcc agtacttgct ggcacacttg ctgtttttat ctttaaaagt ctacaattct
   140581 tagtgattga tactaaagat ccgttgataa atgccaagag atatttgcca ttttatgtat
   140641 tttttgttgg ttttattatt gcgttggtta cgcaatttaa aggtcttaaa catattgact
   140701 ctttaaaata tatctctaaa aatgtttctt taagtttgat aattgcaatt atagttggta
   140761 tttttgcagc tgttattgct gcgtttatta tgagaaatat taagataaat cctaaggatg
   140821 ataaagattt tcattatgct aacatggaaa agctttttgc tgtgcttatg gtgattaccg
   140881 catctgctat ggcatttgca catggctcta atgatgttgc taatgccatt ggtccattgg
   140941 ctgcggttta tagtattgta gaagctggcg gtgatattac ctcaaggagc gctatacctt
   141001 catgggtttt gctagttggt ggcggtggca ttatatttgg tttcgtgact tatggattta
   141061 aagttatgaa aactattggc caaggaatta cagaacttac cccttctcgt ggttttgctg
   141121 ctgaattagc cgctgcaaca acggtagttt tagcctcatc aacaggtatt cctgtatcaa
   141181 ctacacaggt cttggtaggg gcggtgttgg gtgttggtat tgctaggggt gtagttgcac
   141241 ttaatatgcg agttataaat acaatttttt tatcttggtt aattaccttg ccagcaggtg
   141301 cagtcatgtc tattctattt ttctttgcac ttaagggagt atttggagca taagttatga
   141361 cattagaaga aattaaagaa aaaattgaat taggtataga aaattcaaca gttattatgg
   141421 aaggcgatgg ttgtagttgt tcaacaaagg ttatttcgcc aatttttgaa ggtatgtcgc
   141481 tgttggctag gcaaaaaatg gtacttgctg ttatgaataa agaaatcata aatggtacac
   141541 ttcatgcgct tagtattaaa acacgtacac cagaagaaga cacctaaggt gtatttattt
   141601 ttttataatt ttattgctat agcgatatta aatagcctag attaattttt aatagtttga
   141661 tatttattca tatattcatc atatgatgct catgtaaaat ttctatcttt ggatataaaa
   141721 tatttttatg agtttttcta aattaggttt atctgattca attcttaagg ctatcgagca
   141781 gaaaggatat agtgagccat caccaataca gaatcaatcg atacctgcta ttttaaatgg
   141841 taaggatgtc atggcagctg cccaaacggg aacgggaaaa acagcatgtt ttgccttgcc
   141901 tattctcgaa atattatcca aaaaaaaacc cacaaaatcc aatcaggttc gtacattgat
   141961 tctaactcca acgcgtgaat tagctataca agttagtgat agtgtaacga cttatggtaa
   142021 gtatttacct cttaaatcaa gtgtggtgtt tggtggtgtg aagattaatc cccaaatgca
   142081 aagattgtgt tcaggtgttg atattttagt cgctacgcca ggtaggttat tagatttgta
   142141 ttctcaaaat tctgtgaaat ttgatatgct agaaatagtt gtatttgatg aggcagatag
   142201 aatgttagat atgggtttta ttaacgatat taagagaatt ttaaagattt taccgtcaaa
   142261 aaagcaaaca ctcatgtttt cagctacttt ttctaataag attttaacat tagcaaaaag
   142321 tttggttaac aatcctgtag aaatatcagt tactccgaga aattctaccg ttaaagcaat
   142381 aaagcaatgg attcatcctg ttgataaatc caagaaacat gcattattaa ctcatcttat
   142441 tcaagaacat aattggcacc aggttctagt gtttagtcgt acgaaatatg gtgcaaatcg
   142501 tattgtcaat caattagaaa agaaaaagat tagagcaact gcgattcata gtaataaaag
   142561 tcagggtgcg cgtacaagag ctttgttaga ctttaaaaat cacgaagtga acgtattagt
   142621 ggcaaccgat attgctgcaa gaggtattga aattaatcaa ttaccacatg ttattaattt
   142681 tgatttaccg tatgtaccag aagattatgt acatcgtatt ggtcgtacag gtcgtgctgg
   142741 ctcaaaaggt gaggcaattt cattagttag tgctgatgaa gctaagcaat tgtttgatgt
   142801 tgaatgctta attcaaaata aattagatcg tgtaatggta gaaggttttg ttccagatca
   142861 caacctgcca gagtcaggta aaaaattatt gtcaccaaaa aatagaaatt ttaagaattc
   142921 caaaagtcgc aatcgactca gatatggcaa aaatagtagt ttcaagaaaa taaacttaac
   142981 aatgaaaaat tcataaggaa agtaacatga aaattaaatt aatcacgttt gtcatcgtgc
   143041 tatttttaac cccggttcat gctggattat gggagaaaat aactacaata ggtgctaaaa
   143101 tagttacacc aacctcagaa tacttaattg aaacgtcagg ctggaatatt cgagtatatg
   143161 aatggattcc tactgataac cctaatacac gttgcttatt tgcagctggt tcacaaaaag
   143221 gtggagtggc ttgttactca attaatgatt gataaataat taatttattg taggtaacta
   143281 gaactggatt taagctttta tttttaataa atatatcaat gattcgttga tatattattg
   143341 tgattatatt ttgattacga gtatatggtg ataagtgctt cttatttagt tttattataa
   143401 gttcaaatct attttatatc gtgatatgag attttatttt ttgttttaga ataaataaga
   143461 taggggcaat gacctttaaa ttcaagtatt ataattatat ttatagtcgt ttccatcgct
   143521 tagatggtat tatttttctt gacttggtgt atgtttttac attgtgagta acatacattt
   143581 gtaatttatt tataattttg tataagaatt tacagaaagt agtgttacta actaataaat
   143641 ataagtggtg gagatggcgg gaattgaacc cgcgtccgaa aactttcaaa caaaaagtct
   143701 acatgcttag cttgatctat ttttgttaac tacttaccac ccgaccatca gggatataag
   143761 taagcgattt tcaacaagtt ttaaccgaat tacgtgaaaa gaataatcct agcgagtctg
   143821 tgagcgaccg tcattctaaa agtacagaca acttttaggt gacggctagc tatgcagcta
   143881 gagcgtagtt gttttcgttt tcaactatat tttataagta tattttaacg agttatctta
   143941 atcctcggca tgcattcttg agatccaacc cctcgtcgaa gccatgtcat ccccaaaact
   144001 gtattattat aacagttttt tattgaattg tcactcttgc gaattttcgt tttcctactt
   144061 gataaacgtt tgtattagtt ggtggttcaa agtttttatt tgtgatttta atattattga
   144121 ttttaacacc accttgttta atcatttggt atgcgtttga ggtgctaaag caaagtccag
   144181 tatctttgag taaattagca atttttatgc cagctttaaa gctaaattca ttcattttat
   144241 taggagtctg atttttacta aaacgattaa taaaattttg ttgtgcttct ttagcgacat
   144301 cgaccttata aaagcgagta acaatctcat tagctaggac aaatttaata tctcttggat
   144361 ttttaccttg tactattgtt tgttttaaat tggtaatcgc ttctaaactt tggaaactta
   144421 ataattcaaa ataacgccac attaaatcat cagaaattga cataattttg ccaaacattt
   144481 catcaggtaa agcattaata ccaatgtagt tatctaatga ttttgacatt ttttgtacac
   144541 cgtctagtcc ttctaaaatt ggcatggtaa gtatgacctg ttgttcttgt cctgcttgtt
   144601 tttgtagttc tctacctact aataagttaa atttttggtc agtgccgcct acttctacat
   144661 cgctttgtaa ttcaacagaa tcattacctt gaattaaagg atataaaaat tcgtgggtag
   144721 aaatggattg tcctgatttg taacgtttgg aaaagtcatc acgttctaat attctagcaa
   144781 ttgtttgttt acttgcgagt tggataaact ctatcggttt cattttatcc atccactgaa
   144841 agttaaatac aaccttagtt ttatttttat ccaagatttt aaatatttgt ttggtgtagc
   144901 ttttggcgtt ctcttgaact tgtttttttg aaagtggtgg gcgagtttta cttttacctg
   144961 tcggatcgcc aatcatggca gtgaagtcac caattaaaaa taatatttca tgacctaaat
   145021 tttgtaattg cttgagtttg tttattacaa cggtatgccc taaatgtaaa tcaggtgtgg
   145081 ttgggtcaaa acctgctttg atacgtagtg gtttgtcttt tttgagtttt tctttaagtt
   145141 cgtgaaatgg taatatctca ttagtaccac gtgtaaaaat agctagtgtt tgttctatgt
   145201 tcaaatcttt tattgtctga tatgtccgtt acctaggacg ataaactttt gtgaagtcaa
   145261 tccttctaaa ccaacagggc cgcgtacatg gagtttatca gtactaatac cgatttctcc
   145321 acctaatcca tactcaaaac catcagcaaa gctagtggag gcgttaatca tgactgatga
   145381 ggagtttact tctgtaataa aacggcgtga acgagtatag ttttcactca caattgattc
   145441 agtgtgattt gagctatatt tatcaatatg tttaatggct tcactcatcg atttaacaat
   145501 acgaatagat aagattgcat ctaaatattc tgtcttccaa tcttctgcag tggctaaaat
   145561 gattgtattt gatagtttta cagtttctgg acagcctcgt aattccactc cttttgctaa
   145621 gtattgtgca attagttctg gtaatatttt acctactact gagctgtgta ccaacaatgt
   145681 ttcagtagca ttgcatacac cataacggcg agtcttggca ttaaaggcaa tgctaatagc
   145741 tttttgtgta tcagcatctt tatcaatata agtatggcaa ataccgtcta aatgtttgat
   145801 aataggtact ttagcgctgt tactaatggc cttaagtagg cctttaccac ctctagggat
   145861 aatagcatca acataatcac ttgctttgac tagctcaata acagctttac gatcttgagt
   145921 gttaataagt tgagcacaat tttcattaag tcctgcttgt gttatacttt gtttgacaca
   145981 agtatacaga gcatgattag agtgaacagt ctctgatcca ccacgtagga taatgctatt
   146041 tcctgatttt aaacaaagtg ctactgcatc aattgtaaca ttaggtctag attcataaat
   146101 aacgcctatc acaccaagtg acacgcgcat tttgccaact tggatgccac ttgcttggta
   146161 ttttagatct gtaatttcac caatagggtc tggtaggttg gcaatttgat ttaagctttt
   146221 aataatatta ttaatacgta tattatcaag catcagtcta tcgagtagtg ctatgtttag
   146281 tcccttattt ttactattag caaggtcttt tttattggct ttaagaatac tccttctatt
   146341 ttggtcaatt tgattagcga tattgattag tgcattgttc ttagctactg ttgtagcacc
   146401 acgtaatgtt tttgcagcgt tttttgcatt ttcgcctaat agagtaatta gattttttat
   146461 tgagtccatt gtatttcccc agctaaactt agtagtaatg tatgtagttc atcaatcaca
   146521 ttaagattat ccatgttttt gattgaacgg tcaatacatc ctagtgataa taatattttt
   146581 tgaaagtgct gataagaatg atgctttaat gcattggtaa taataggttt tcttgtgttc
   146641 cacacttgat ggtttttcaa aactatgtta gtatctttaa cttgtctaag ctcaattgac
   146701 atttcagtta ttgatttaat ttctaggtat aaagcatggc ttagttgaat tggcatgatt
   146761 gtattagaga ttaaagtttg ataaatttta ttaacttgat tactattacc aaataaagct
   146821 gcatcaatta aatcataaac agtatattta gattgttgat tagcttgttt aagatattct
   146881 tgagtattaa ttttgccatt tgggtaggct atttttagtt tttgaattgc ttgcatagag
   146941 gcagtcaaat taccttctgt gcaaaaagcg atattttgtg caatttctat attatcctta
   147001 agccctaatt ctgccatttg ttttgtaatc caatcaacta aatgattatt ttgtacttca
   147061 aaatgctgga taagactacc agtttgttct agtattttga accatttgct tttttgttgt
   147121 gctatgttta attttccagt agatacaatt agtaaaatat tattgggtaa agtgttgaca
   147181 atttcaacta ggttattagc acctttaata ccaattttac ctgtttttaa tcggcattca
   147241 ataatacgtt ttggtgaaaa aagtgaggta gttgagattt cttcaaaaat ctgattccag
   147301 tcaaagttac tatcaatttc aaaacttact ttttcatcaa actttttttg ttttgctgct
   147361 ttttttattt gtgctaaact ttgttcaatg agtaatattt cagcaccaaa aataaaataa
   147421 atagcatcaa gtttgttagc tagttgagta ttaagttgtt gaggtttaat tttcattaag
   147481 tttgtataat cttcttaata gttgtctaat aattaaacga cgtaattgtt gataaccttc
   147541 ttcgatttga agtctatttg cttggtatgc atctatttta ttcaagtatg tgttagcact
   147601 gaaagtttta gatagcaata gttttttgtt atgattaaaa actttaatag gtatgtttag
   147661 gtttaatgta tagctactag cttcattact tgaagtatat gaaacagttc gttgattttg
   147721 attttcagta cccacttgaa taactagaat tttatgcatg ttttgattaa aatgtttttg
   147781 caattcatta gcaaaaatat tattacggtt actggtgata gaagcattta ttgttgaatt
   147841 tgtatatggt gtatgaaatc cacaagaact aaggatcgtt accataatag ctaataagtt
   147901 aatttttaac atgattcaaa agtgtttatt taatgtaagt taagaattat ggcagaattc
   147961 taatttattt gtagataaac cttgaaaaaa cgtcattgga cccatatact agtcattaca
   148021 atagggtata gtcattctct tattttttta ttatatttta taacattatg tttaagaatt
   148081 tattactttg gttaattttg ggtggtgtcc ttacttcgat ttttagtcaa tcccagatgg
   148141 gtgaccagaa aaatgatatt acttattctc aatttattca aaatgttaag caaggtgctg
   148201 tatctcaagt aacgattgct ggtagtaata ttactggagt gggtactaac ggtgaacaat
   148261 ttgcaacata tagtccaggt gatttaggtt tgatgggtga tttattgaat aacggcgtta
   148321 acgtagttgc taaatcacct gaaaaagaag gatttttcaa acaattaatt atctctttag
   148381 ctcctatttt attattaatt ggtgtggttc tttatactat gaaaggtgct ggtggtgcta
   148441 tgggtggaaa aaacccaatg agttttggca aatcaaaagc acgtcttatt actaaggatg
   148501 agtctaatat tacttttgat gatgtagcag gtgttgatga ggctaaggat gacgtgagtg
   148561 aacttgtaga ttttttatca gatcctggta aattcactaa agtaggcgga aaaattccta
   148621 aaggggtgct tttagtagga cctccaggga caggaaaaac cctattagcc aaagcgattg
   148681 cgggtgaagc tgatgtacca tttttcttta tttcaggttc tgattttgta gaaatgtttg
   148741 taggtgttgg tgcgtcacgt gttcgtgata tgttcgaaca agcaaagaaa aatgcacctt
   148801 gtattatctt tattgatgaa attgacgctg taggccgcca acgtggtgct ggtatgggtg
   148861 ggggtcatga tgaacgtgag caaacactca atcaaatgtt ggttgaaatg gatggttttg
   148921 agggttctga aggtgttatt gttattgcag ccactaatag accagatgtt ttagatcctg
   148981 ctttattaag accaggtcgt tttgatcgtc aagttatcgt gggtttgcct gatattaatg
   149041 gtcgtaatgc gatattaaaa atacacatgc gtaaattacc tattgcaaaa aatgttaaat
   149101 cgattaatat tgctaaagga acaccaggat tttctggtgc agacttggct aatttgacta
   149161 atgaagctgc gttaattgca gcaagcaaag ataaaaaatt agttggtatg caagagtttg
   149221 aaaaagctaa agataaaatt atgatgggtt ctgaacgaaa atctatggca atggatgaat
   149281 ctgaaaaaga aatgacagct tatcatgaag caggacatgc tattgtaggt agattggtac
   149341 ctgaacatga tcctgtttat aaagtaagca ttattccaag aggaagagca ttaggtgtga
   149401 ctatgttctt accagaaaaa gatagctata gtatttccaa gcgtaaacta aattctcaag
   149461 tagcatcact ttttggcgga cgtattgcag aagagttgat ctatggtgta gatagagtaa
   149521 caactggtgc aagtaatgat attgagcgag caacagaaat tgcacataaa atggtaaaac
   149581 aatggggcat gtctgaggtg ttaggaccct tatcatatgg tgaagacgaa ggtgaagtat
   149641 ttttaggtcg acaagtcacc aaacacaagc atatttcaga ggatacattt agaactattg
   149701 atagtgaaat tcgtaagatt attgatagta attatcaaat agctttcaag attttaaaag
   149761 gtaataaaga tatcttattt gaaatgacta gggctctcat ggagtttgaa actattgata
   149821 aagaacaaat tgatgatttg atgaatagaa aaccaatacg tgaatcagct gttgttattg
   149881 attctaatgt cgcttctact gaattaggat caggagctac gtttgatggt agcaatcaaa
   149941 attctgatga aaaaccatta aataagggtt ctactgaaca ggttgcttaa ttttttgttt
   150001 ttgaatatta tctaatcaca taatagtgca ttcatctaat gtaatgatta tgggtgttct
   150061 taatataaca ccagattcat tttcagatgg taatcaatac tttactgttg atcgcgccat
   150121 taattatgct aaattgatga ttgatcaagg tgctgatata attgatattg gtggtgaatc
   150181 aactagacca aacgcactac aagtatcaat tgatgacgaa attaatcgcg ttattcctgt
   150241 tattaaagta ttatctaagt taggcagcgt gccaatttct attgatactt cacaagcaaa
   150301 aattatgcag cttgctattg aagcaggagt aagtatgatt aatgatgtac gtgctttaca
   150361 agcgaaatct tcccttgaag tggtagcatc aagtaataag gatgtgtgtc ttatgcatat
   150421 gaaaggtagc cctaaaacca tgcaaaataa tcctatttat actgatgtta ttgatgagat
   150481 aaaatatttc tttgatcaaa gaattgaaga ctgtattagc gctggtattg accaaaataa
   150541 gattattcta gatccaggtt ttggctttgg taaaacactt aatcataatt ttgaaatttt
   150601 acgtcgtctt gacgagtttc aaagttttgg cttgaggatt ttagtaggta tgtcacgcaa
   150661 atcaatgatt ggtaatatcc ttaataatag aaacatagat ggaagaatga ttggtagtgt
   150721 aactactgct ataatagcat ttcaaaacgg tgcaaatatt gttcgtgtgc atgatgtttt
   150781 agatactaaa gatgcattta agattttaca aagtgtagta ggagattaag ttggataatt
   150841 attttggtac tgatggtata cgtggcaagg taggtataga gccaattacc gctgattttt
   150901 ttttaaaatt aggttggtca gtcggctcag tattagccca acaaggcaaa gctagtgtta
   150961 ttattggtaa ggacacccgt atatctggct atttatttga atctgcactt gaggcaggat
   151021 ttttatctgc tggtgttgat gtgggtttgt taggacctat gccaacgcca gcagttgcat
   151081 atttaacaca aacttataat gctaatgctg gagtagtaat tagtgcttca cataaccatt
   151141 ttcaagataa tggtgtaaag tttttttctg ctaaaggcct aaaatttagt agtcaagacc
   151201 aaagtgcaat tgagaataaa ttaactaagc ctatgattaa tgtgggtgct gataaaattg
   151261 gtaaggctta tagacatgaa caaccacttg ggcgttatat tgaattttgt aaatccactt
   151321 ttgatcgaac acaaagtctt ttaggactta atatcattat tgattgtgca aatggcgcaa
   151381 cttatcacat cgctagaagt gtattttcag aactgggtgc aaatattcat atcattaata
   151441 atacaccaga cgggtttaat attaatgagc gttgtggtgc aaccaatacc aagcatttac
   151501 aacaagttgt attagaatta aaagcagatt tagggatagc ttttgatgga gatggtgatc
   151561 gattaataat ggtagatgaa aatggagaat tagttgacgg agatgaacta atattcatta
   151621 tcgctaaagc ttggcaatct caaggtaggt tggttaataa tacagttgtc ggaacaaaaa
   151681 tgagcaatct aggtatgcga tatgctctaa gagatttaaa tattcaattt attgaggtta
   151741 atgtgggaga tcgttttgtc atggagcaaa tgcaaaaaag tggttctata ctaggaggcg
   151801 aaggttcagg gcatattata tgcttaaata agacaacttc tggcgacggc atgatttctg
   151861 ccttacaggt attggaagta ttagtcaaaa gccaatctag tcttactcag ttaaaacaat
   151921 caatgaataa atacacacaa attttaataa atatcaaaat tcagacacaa gttaatttag
   151981 agaatcatac taaattacaa caagcccaac ttgaagttga aaaaatgctt ggtagtgaag
   152041 gaagggtagt gattcgtgct tcaggtacag agtcattaat tagaataatg gttgaagcca
   152101 aaaataagat tattgctaaa aaaggtgcta aaaaactatc aaatgttttt aaatagagta
   152161 aagcaaaagg aataattaag tatagatgta atttagaagt aacctatttt gaatagtggt
   152221 ttttaattga ttatccatcg caattatcaa ccagttctct attactgaca ataatacaat
   152281 aataagaaaa tatgcttata tactattttg ctctgacagc ataaaaatac cattatacta
   152341 ttcatcagat catctattag atctaataat tatggttcct ctctttgtaa aaagtttggt
   152401 tattaatttt aggatttttt tgcgttgtga ttttgttgaa tttttgactt tctatgaaaa
   152461 tcttttattc ctgatttctt actgacttat atttaccgaa aataatatca tataaaatat
   152521 ggttgtatta ttgtcatttt ttattttaaa aaatctttta cttaatataa gatattgaag
   152581 ttaaaaaaaa ttaattacac aattcaatca ttatagtaag tgaaccttat atttagtaca
   152641 tataatagat aatattatga attaattatg ttatataaaa tataaattac gtattgtaat
   152701 tgggttaagt gatttattaa gttatcaaaa atgaaagata aatagtaact gtttgagggt
   152761 tgttagggtt ttttaatagg tttattagta aagtaaaata ttgtagcaag tactcaaaaa
   152821 ccaagtgtta aacttgaata ttgtcaaaaa ataatttgag atagtagaaa gtagggaaaa
   152881 tagatgaagt taccttccaa taaatgaatc ttattattaa aagcttattt gttacaaaga
   152941 atagaaagat atcttgatag gtgcctatag tggttgtatt caaaagagtt tggctgcaat
   153001 atcttcctta gttaatacct taataaatac cattatatta accagttagc agttaatacg
   153061 gcgattaaaa atgtagtagt actgataaaa aatactagca tatacgctta gatctttgtt
   153121 taccacgtat ttattataaa ttagtataga tattctcata atttatgata ctactaagat
   153181 agtagtagtt tacactagtt aagagatagt agtctatatg actggtaaat agtgaggagt
   153241 atgtattttt ctaatacgga attattttta attagtttga ttttcttgtg ggtaggattt
   153301 gtacgcaccg ggttcggatt tgggggtgta tcgcttggtt tgccactaat gttattgata
   153361 ggttcatcac ctgtttattg gctacctata attggaattc atttgttatt tttttcatca
   153421 ttgactttat ttaagtctat taaggaggtt gattggtgtt atcttaaata ttcactttta
   153481 tggattattc caccaactct gtttgggtta ttctggctgt tgtcactatc tgataaggtg
   153541 atgattgtgt ttgtgtattc aattacgatt ttttattcaa ttatttggat ttttaaccaa
   153601 aaacttactt cgtatcgggt gtgggtagat aaattattat taatactagg tggttatgtg
   153661 acaggtactt cgctgattgg agcacctttg attgtagctg tatatattcg ttatgtagca
   153721 aagaaatatt tgcgtaatac tttgtttgta ttatggttta ttttagtaag tattaaaatg
   153781 agtgttttta tagcatttgg aataaagatt gactggcaat tatctttgag tttaattcct
   153841 attgcggcga ttggacatgt tgttggattg aaattacacc aaagaattat agaaaatgac
   153901 gatttattta gacactgggt aggcggtata ttattgctga ttagcttgat tggtatttta
   153961 aaggttgtta tgtagaataa ccatctcaag tattaatgat gaaagaaatg taaggtagat
   154021 agattcaagt aaatatggtg gttaatgtgg tattcatacg aaactattaa gacttattta
   154081 attcaattta aattttaata taaaaactgt cggaattaat gtaggacaat gtgtgtgtta
   154141 aaggttaatt agaattaggt taaaatcata gttatgaatg aatatgtttt aatattggtg
   154201 agtacaattt tggttaataa ctttgtatta gtgaagtttt taggattatg cccgtttatg
   154261 ggagcgtcaa gaaacattga taccgcgatt ggtatggggt ttgctacgac ttttgtattg
   154321 actttagcaa gtatttctag ctatttaatt aatacctatg ttttagttcc atttgagatg
   154381 gaatatttaa gaaccattgc ttttattgta actattgcgg gtgtggttgg gtttactgaa
   154441 ttagtagtta acaaaacttc ccctacttta tatcagtctt taggtgtatt tttaccattg
   154501 attacgacta attgtgccgt attgggtgtg gcattattaa atgttaatca agataatggg
   154561 tttttagcat caggtgttta tggttttggt gttgctattg gattttcatt tgtattggta
   154621 ttgttttcaa ctatccgtga gcgaattgat gtggcggatg tgccattgac ttttaaaggt
   154681 gtacctattg cattaattac tgctgggcta atgtcaatgg catttatggg ttttattgga
   154741 cttgtttgag tttgtttgag tttgtttgat tcagtcttaa ttttctctgt ttttacttta
   154801 atattaggtt taattcttgg gtatgctgga gttaaattta aactaaagga taaccctttg
   154861 gttaatcaaa tagatacgat tttgccacaa attcaatgtg gtcaatgcga ttatcccgga
   154921 tgtcgtcctt atgcgtgcgc aattgctagc ggtgaagcga aaattaatca atgcccacct
   154981 ggtgggcaag aagtagctga tgctctagca gaacttttag gggttgaaac tttagaactt
   155041 aatgctgagc atggtgaaac taagcctagc cacgtggtat ttgttgatga acaagcttgt
   155101 attggttgta ctttgtgtat tcaggcttgc cctgtggatg cgtttgtggg tgcttctaag
   155161 atgatgactc aagtaattat taatgaatgt acaggatgtg atttgtgtat tcctgtttgt
   155221 cctgttgatt gtatttatgt gaaagaaatt actccaaatt taattacatt tgtgtcagat
   155281 attattaagg ttaaacatta gatatgagta attattcatt taaaggtgga attgttatta
   155341 aaaatcctta tttagtgaat aaggttgaga ttattcaggc ttcattgcca aaaaagataa
   155401 ttttgccttt gcagaagttt gatgggaagg caaagccttg tgtaagtgtt ggtgattacg
   155461 tacttgttgg gcaagttgtt gctagtaccg agagtggttt tgatgtatca agccatgctt
   155521 caatttctgg tgtagttttg agtattgata cacaagatat agtacacaag tcaggattta
   155581 aatttcagtg tattactatt aaatctgatg gtgaagataa gtggatagat aataaaggtg
   155641 gtaatgttga ttttttgcat tactcaaagg aaactctagt tggtattatt caaaaatcag
   155701 gtattgtagg aatgggtggt gctgggtttc caacccatgt taagataaat aaggttcttg
   155761 attgtcatac tttgattatc aatggtactg aatgtgaacc aggcgttatg tgtgatgatg
   155821 ctttgatgca attttatcca aaagaaatta ttcttggcat agaaattcta ttatatattt
   155881 gtggtgcaga tcgtgctatt attgctattg aggatgataa acaagcagct tatcaagcgt
   155941 tattaactgt taaccgtaat gataggatta atattaatca aattccaact aagtatacct
   156001 ctggtgctga gaagttactc attaaggcgc tacttgatat tgaaatttta tcagggggtt
   156061 ttgctattaa tgaaggtatt atttgccaaa atatatccac cactaaagca gtatttgatg
   156121 cagttattaa tcataaacca ttagtatcac gtattgttac ggtgacggga gatggtgttt
   156181 atccaaataa ctttgaagtt cgtttaggcg catcatttga gcatcttatt tcaatgacca
   156241 gtcctaatac aaaagaacat aattatcgta tgggtggtat gatgatgggt attgatgttg
   156301 ttgatattaa tatgcctatt ggtaaaacta ctagtgctat ttttgttaat aataaagtgt
   156361 ctgaacctat tgttcaggaa tgtattcgtt gtggtcaatg ttcagaagtt tgtcctattg
   156421 gattgcttcc acaacaactt tattggtata ttaaaagtaa gaattttgaa aaagctttga
   156481 attataattt acctgattgt attgaatgcg cttgttgtga ttatgtttgt ccaagtcata
   156541 taccattagt gagttatttt tcttttgcta agacgtttag taagcaacaa actatagaac
   156601 agaataaagt taatactgct agagaaagat ttaaatatag agagtatcgt cttgaacgta
   156661 acaagcttga acgtgcacag gtgatgctag ataagaaaaa agctctaaaa gaaaaaatgg
   156721 caaaagagca gtttcaaaaa caaaaaatca ctgaggcaat acagagagta aaacaagcaa
   156781 aggataaaat ttgacactaa tattgagttc aacatcatgg atgatgcgtc aagtgattta
   156841 tgcattagcg ttaggtatag ttgtatctta ttatttcttc ggttggggta ttgtattaca
   156901 aatagtgcta ggtgtaataa cagctgttgc agttgaatca gcatttttag catttagagg
   156961 gcgtgatatt attagttcaa ttagtgatgg ttcaataata ctcacagcaa tcttattagc
   157021 tatctccatt cctaatattg caccatggtg ggtgataata gtaggaatta gttttgcgat
   157081 tatttttggt aagcaattat acggtggttt gggtaataat ctatttaatc cagctatgtt
   157141 agggtatgta tttttgctga tttcttatcc attacaaatg agtacttggc caattaattt
   157201 tttaagcttt gatcaagcct tagaggtggt atttaattta agtaatattg atgcaattag
   157261 tggcgcaact agactagatg aaataaagaa tagcttatca ttgtcaaact caattaaaca
   157321 attagaaata cattttccct cacaggtatg gattaatgta gggttctttt ttggaggact
   157381 atatttatta tttagaaaaa ttatttcttg gcatattcct gtttcgtttt tagtaggtat
   157441 tgtgataact tcagtattgt tgtggataag taatgtagat ttatatatac ctatgcaaaa
   157501 tcatattatg ttaggtggta caatgctagg tgcatttttt attgcaactg atccagtttc
   157561 agctagcaca acgataaacg gtagaataat ttatggtttt ttaattggag tgctcattgt
   157621 tattatacgt acttttggtg gttatcctga tggaattgcc tttgctgtac tgttaatgaa
   157681 tatgactgta ccattgattg atgtttatac acaacctaag gtatttgggc aataattttg
   157741 cgtgttattt taaagtcagg ggcgctattg tttgtattca cagtagtgag tatatttttt
   157801 gtttcgctta cacaaatcaa gaccaaggat attatcattt ataatgaaaa gcaattacta
   157861 attcaacgtt taggtgaatt ggttagtggt tatagtaatg atatattact agataaatat
   157921 tctaaaacac ttaaattaca tggtatattg caaaatatta atatttatcc agtaaaaaag
   157981 aatcatcaga tattttccta tttgattgaa cacacttatc ctaatggtta taatggagat
   158041 attcgtttat taacaggtgt tggtattgat aaaaagctcc tgggtgtccg tgttataatg
   158101 cataaagaaa ccccgggttt aggtgataaa atagagctaa aaaaatcaaa ttggattgaa
   158161 caattttttg gtctttccct tttaaaccca gttaagaaaa attggaaagt aaaacgagac
   158221 gggggtatat ttgatacctt cactggtgca actatcaccc cacgtgctat tgttactgca
   158281 acttatcaag tcttagaatt actaaatgaa ccttgtatac ttagcaaaaa accatgcaat
   158341 taaaagattt tgattttgat ttaccagctt ctcttattgc tcagcatcct attaaaaata
   158401 gaacagattc acgacttttg atcaaaagat caagcatcat agatatacaa tttaaccaaa
   158461 ttggtgattt ttttcaatca ggcgacttat tgataatgaa taatacaaaa gttattcctg
   158521 cacgcttgtt tggaacaaaa gaaacaggcg gtaaagttga aattatgatt gaacgtatct
   158581 tggatgaaaa ccaagtactt gcaatgatta aagccagtag agcgcccaag attggtagtt
   158641 gtattttctt agaaaacgat gttaatataa tagtatatca aaaagataat ggtttttata
   158701 cactaatatt tgaaactgat tccttgtttg atttacttaa taatatcggc cataccccac
   158761 tacctcctta tattaaaaga acaaataatg tacaagattt aagtcgttat caaactgttt
   158821 atgcacaaaa agatggtgca gtggcagctc caactgcagg tctacatttt gatgatagtt
   158881 tattagcaca attaaaaata caaggtatcg atcacttatt cgttacatta catattggtt
   158941 caggtacatt tactcctatc agaactgata acattaaaaa ccatgtaatg cacagtgaga
   159001 tatttgaaat tagtcaagta actgttgata gaattaatct aactaaagca aatggtggac
   159061 gtattattgc agttggaaca actactgtaa gggttttaga gtctagtttg aaaaatggta
   159121 aacttattgc tcagaatggt gagactgata tttttatcta ccccagttat cagttcagaa
   159181 ttgtggatag tttgatcact aattttcatt tgccaaaatc ttcattatta atgttagtaa
   159241 gtgcttttat tggacgtgat aaaatgcttg aactttataa acacgctatt gagcaaaaat
   159301 ataaatttct ctcttatggt gatgccatgt tcttggaaaa aaataatgat ttatgagaat
   159361 atatgaatta ctctaggaat tgaatttagt aaagtctatt gggtttaagg tatatactaa
   159421 ataaaatatt aactaattta gtgaatgcat attgaatgaa aaggctgagg ttttttagaa
   159481 ttattgatat tataaatatg aagcagttaa tattaagtta tttttatgta gataaaaata
   159541 acattagata ttttatagtt tgaaaaataa gtaatattaa tattatttga tgtaaattat
   159601 taaatagaat caaattgatg ttaaattttt aatactaatt ttgattgtgg gctttttata
   159661 aaaagtctgt gcataactat aaagtatatt acttatttgt agtttaggta tttttatgtg
   159721 taaagaattt attgaagaag tctaagaagt tttattttgc tagttttaga ggaaaatact
   159781 gtgtaagtct ttatcaaata ggtaattaaa cgtgttcatt tgcaatcttt tttaatgccg
   159841 gtacagataa gttaaatttt tttgctaatt taagtgtgcg ttttagtctt gtaagtgcaa
   159901 atcttcccat acagttatgt tctaagtcac tttcaaagat ttttattatg ccttgttcta
   159961 attttttttt atcaaaggtt tttccagtaa gtttggtttg tatggctatg atatcatttg
   160021 atacattact cattaaactt gagtgtttgt tacgtaaatc gttaatattt gcatctgact
   160081 caatgactaa acctacaata ttagtggtta agatataaag attttttaac accaactcaa
   160141 ataataattc ttcttcggaa ttaataatat gagaagggat gttaatcaaa gccaaagaat
   160201 caattagaat ttttgctttt ttaccataaa taggagatga aattaatact ttaggatcta
   160261 tgcctttttt tttctcaaac cagactgaga ttacagtagg gtctataaag ttgtgtgttt
   160321 gccaatcacg aggtaagagt tcgttttgta tcatggtaat tctatctttc catttatcag
   160381 gggtggaatg tagtgcattt tgtaaatcgt cttctgctgt gcaaattaat acaagctctg
   160441 gattgatggt attggctaac tcgttaatat tggtttgtct ggtaatggga taaacaggat
   160501 aattattttt taaaaaagca cgagagaaaa cgcttcctaa ttctccaatt cctagtacaa
   160561 taattggctt tttcattcta atatttcaag taatgtttca ccaatacttg tgggtgttgg
   160621 cgcaattgct acgccgactt ttcttaaagc tttgatttta tcgatcgcct tgccagtgcc
   160681 agcactaata actgcacccg aatgtcccat acgcttgcct tgtggcacat ttaagcctgc
   160741 aatataagaa atcacaggtt tagagatgtt agattgaata tattctgctg cttcctcttc
   160801 ggttgatcca ccaatttcac ctatcataac gatagacttg gtttgcgagt ctgtttcaaa
   160861 tagagctaga cagtcaataa aatccatccc ttgaatggga tcaccaccaa ttccaataca
   160921 ggtgctttgc cctaatccta ctaatgtagt ttgatgtacg gcttcatagg ttaatgtacc
   160981 tgagcgtgat atcaccccaa cactgccagc tttatgaata ttgccaggca taattcctaa
   161041 tttgcactca tcaggtgtaa taacacctgg acagttagga ccaatcaaag ttgaatctga
   161101 tttttttaaa atagctttaa ttttaagcat atcttgtacg ggaatacctt cggttataca
   161161 agcaatcaca ggaatgttcg tctcaattgc ttcaagtatt gaggcgtaag caaagcgtgg
   161221 tggtacataa attatgctag cattagcgag tgtttcatta atagcctctt tagttgtgtt
   161281 aaaaacaggc aagtttaaat gtctttgtcc gcctttattt ggggttactc caccaacaat
   161341 ttgtgtgcca taaataatgg attgcttaga gtgaaatgtt ccttgttttc ctgtaaatcc
   161401 ttgtgtaata acgcgtgtat ttttgtcaat tagaatactc attttgctag ttttataatt
   161461 tttatagtag ctttgtttaa atcagattca gtatgaatgt ctacctttgc tttatctagt
   161521 aatttaagtc catcagtggc attagtgcct tctaggcgca ccacaattgg caaggtcaat
   161581 ctcacttttt caattgcttg taatatgcct tgtgcaatta aatcacaatg cacaatacct
   161641 ccaaaaatat ttactaatat acctttaata ttttcctcgg tttgaatgag ttcaaaggct
   161701 ttagcaaccc tgtcagcagt tgtgtcccct cctacatcta aaaaattagc aggcgagcca
   161761 ccaaaatgct caattaaatc catcgtagcc attgctagtc ctgccccatt caccatgcaa
   161821 ccaattgttc cattaagtga aatataatta agatgatata tattagcaag cctttctttt
   161881 tcatcttctt gtgatatatc acgtaacgca ataatatctt tatgtcgata tagtgcatta
   161941 tcatcaaaat caatctttcc atcaagtgct aatagtttgt tttctttagt aataacaagc
   162001 ggattaattt caatcaaatt aacatctttt tgagtaaaga tttcatataa acctaaaaga
   162061 atattgttaa actgcttagt aaatttaaag tgaaggtcta gttttttagc cataaaagca
   162121 caatcttgta cagataaatg ccccagtggg ttaatgccaa atttaataat ctgattagga
   162181 gtttttctgg caaccttttc tatatccata ccacctttag tagaggctaa aacagtgatt
   162241 tttttcgttt gtctatctat caacaaacca agataaaatt catgtgtaat attctcccct
   162301 atttcaatta ataactgact aactggtaat cctttagcat atgtttgtgg agtaataagt
   162361 tgtgaattta ataattgact acatgcattc ttaacttctt caatgctacg acataaaata
   162421 ataccaccac cctttccacg tcctcctgca tgaatttgag ctttcacaac ccaaatacta
   162481 ccccctaaag ttttgcaagc atcgctagct tggtcaacac tataaataag aataccttta
   162541 ggggtttgaa tgtgtttgtg gttaaataat gttttagctt ggtattcgtg tatatgcata
   162601 agtttatctc tcattataca ttttctaaaa taaatattct tggtctcttt tcttttaaaa
   162661 ttttaataat tttctaaaat aaataatctc tatcattttt ttgttaaggg tttgtttata
   162721 tcttttaata gaaaattacc aacaagtaga acctgtaaag aaatttttaa taacatttta
   162781 gacttattat atttatagtt ggttttctgt attgtagata caatctaata atctatttta
   162841 caactaaaaa tattcctttt atctgaatat aatgcaatta ggtattcttt ttagcttata
   162901 aatcttaatt aagatttaac actttgttta aattctggaa taataatttt attatttctt
   162961 tcaaaatgaa agcatccaat tataggtgaa taattttata tatctgtaag gatttggcgt
   163021 gtcctatata ttttataatt agtaagttat caatgtttat gtttaaaaat tattacttaa
   163081 atattagtaa taatggtttt gattatggtt taaatattga tatgataact ttaaattctg
   163141 ttgtttaata aaagagctaa taaattcatt tttattagga gttgttactt tttttgagaa
   163201 gtttctttta ggtcattata tatatgatac aaacgagggc tattttacaa ataaaatttg
   163261 cgtaaaatga attattctgt ttcttaaatt ttttaaaaat ggataaatat tctattaacc
   163321 aattcaaaaa cggcttaaaa cttatgttag atagtaatcc ttgttcgatt ctaaataatg
   163381 aaattgtcaa gcctggtaag ggacaggcat ttaaccgagt taagtttaaa gatttaatta
   163441 ctggtaaaac actcattaaa acctttaagt ctggtgagtt tttagaaggt gctgatgtga
   163501 tggaattaga tttacaatat ctttataatg atggtaatgc atggaatttt atggatccac
   163561 attcatttga gcaatatatc attgatggta ttactgtgag tagtgttaag ggttatttgg
   163621 ttgagcagga tatatgtata gttacgctat ggaatgataa tcctatttca attacaccac
   163681 ctaatcatgt tattcttgaa gtgtttgata ctgatccagg tttaaaaggc gatactatag
   163741 gtgcaagtgg taaaccggct acaatgaaca caggagttgt gttacaagta cctctttttg
   163801 ttagtattgg tgataaagtg aaagtagata cacgtattaa tgaatatgca gggcgtgcat
   163861 aatattatct tacactatct aaaaattttt ggaatgagta aggctcgttt ctttgtttat
   163921 gatacgaaat acacttatta aaaaacagct aattattcaa aaaattagac agttctttaa
   163981 ggaacaagaa gttctggaag ttcaaacacc tatactacaa aatacatcaa ctagtgatgt
   164041 ttatattgat agtatttcac tgactattaa tactgatatt ggcatacaaa gtatccagta
   164101 tttacatact tccccagagt tagaaatgaa aaaactttta gcacaaggta gtggggatat
   164161 ttatcaaatt tgccaagtat tccgtaataa tgaatatggt aaacaaaatt ttaatgaatt
   164221 tactctgctt gaatactatc gtttgggttt tgatattcat cagttgatgg ctgatatgat
   164281 taatttattg aaaatgttag gtattcaaga taaagtgtat caattatctt atgctcaagt
   164341 ttttaatcaa tatgcgaata ttgatatttt aaatactgac attgcttcac ttaaaataat
   164401 cgcctcaaaa ttagggttga gtactgattt tgtttggatt gaagatttac aaatgttatt
   164461 atttgtgcat ttggttgaac caaagttaaa aaatttaccc ttatgtttta tttatgatta
   164521 tcccaagtca caatctacac ttgctaaagt taaaaatcaa gtagctaaac gttttgagtt
   164581 atatttgaat ggcgttgaag tagcaaatgg ttatgatgaa ttacaaacca aggatgagta
   164641 tcaacaggtt tttatatgtg aaaataataa gcgtaaacaa tttagtaagc ttatatctca
   164701 aattgatgtg tcatttttgt ctaagcttag taaacctttg cctcaatgta ctggagtagc
   164761 gataggtatt aatcgattat taacacaaat taattaaatt agttaaaaaa ataaaaaatt
   164821 tatgattaaa tttatctatc ttattcttat attttctttg ccaatacaag cattgcaaat
   164881 tctacaatcc attaacgaca ataaagttat ccatcaacta gatgtgcctc agttagatac
   164941 gttattgtct gctgaacaat tattaactaa attaaaaaaa tcagctaagc gtggtgatgc
   165001 taggtcgcaa tttagtttag ctaatatgta taacaatggt attaatgtaa aaaaagataa
   165061 taaacttgct ttttattggt acttacaagt agctgaacag gattatgcaa gtgcgcaatt
   165121 taatgtagct aatagttatt tttatggctt aggggttggt aaagacttgg agcaagcatt
   165181 taattggtat aaaaaagcag taaaaaatgg tcatgtacaa gcgcaatata acttagcaac
   165241 tttatatcta aatggtgatg gtgttgaaaa aaatagcaaa caagctgttt attggtatca
   165301 aaaatcagct gaacaaggtt atttagaggc atactatcat ttagcattac ttcaattgat
   165361 aggtaacggt attaataaag acattaagaa tgctttaacc gtgttacttg atttgtcggc
   165421 taaaggccat caagtgtcgc agtatcaatt gtatttgatt tacaataaag gtgaaattgt
   165481 tgttaagaat gatatattag ccaaaactta tttacttaaa gctgtaaaag ggggatatgc
   165541 taaagctcaa tatcaattag gaaaaagctt tcttgatcag ggtatggata gagaggaggc
   165601 tgttcattat ttagaattag cggctaatca aaaaaatgtg ttagcgttta aattgttaga
   165661 aaaattacaa tctaaattac agaaagaggt acaaaataga cagaaaaaag atacaataca
   165721 tcttgctaca aatatcgacc aatcaatagt agctgttgca tctcctatgg tgggtatgcc
   165781 taaacaggat atttggcctg ttaagttcaa tttaaataaa caatttaacc atgttgcagc
   165841 taatcttatc cctaatctaa gcgatattgc tagctcgctt agttataata ttaaatcaca
   165901 tgttaattta gaggctttac ttctcaatgc taagcaaggt aatcctattg cccaatataa
   165961 tttaagtatg ctctattaca agggtgaagg tgtacgtaag gataatagag ttgcgtttat
   166021 attaatgcag caatctgcta atcaaggtat tactcagtct caaaacaccc tagctaaaat
   166081 gtatatgaat ggttctggta ttcatataga ttataataag gcatattatt gggcaagtgt
   166141 aacaactcgc aaaggtagtc aacaaggtaa gcgtatttta ctgtacctaa tcgctaattt
   166201 ataatttttg ggaagatata gtgttaaaag atataacaga catgtatgca gtgggagttt
   166261 ttatgcgata attactggca ttgttatttg cataaacttg agattgaaga tacgggtgat
   166321 atttattaat atagtttgtt attatataga tgaataaagt ttacaatact tgtattatga
   166381 aatgttccaa caacttgtgc tagattgttt caatattaac ttggatttag gttataaatt
   166441 taattggtta cagcgtcata tgcttctcaa cttttgtatg agaaaaagac attatttaat
   166501 tagtgatata gaaactatat atttatcaga tatttttata agtgaataca tttttaaggt
   166561 aataaagtga ataaaaaact aggttgattt acataccaat taactgtttg agattatgga
   166621 taaatacccc ttattactac taggatcttt ggttaatgtt attttttaaa tatatattaa
   166681 tagctatttt tgctgaattg gttaagaatg gaacaccatt gaaatagatc atataggcta
   166741 ataactcctt aggaaaaatc tactacttaa ttagtatctg taacttcgta gaagaaaaga
   166801 ttatgttcta ttgaatttat aaggataaag cttaaattgg tttaaaatat tggcagggtc
   166861 aataaaaata tttggtacat atggacagga gagtggaaag ttgaagtatt aaactaacaa
   166921 gattaaattt tattaaccaa aatattcatt cataaaaaga aagatgagtt aaagttgtat
   166981 ttgccttaaa agaaaaaatg gacaaaacaa gcataaataa agtggtatta gcctactcgg
   167041 gtggactaga tacaagtatt attgttaaat ggctacaaga tacttatcag tgtgaagtag
   167101 ttactttcac agctgatatt ggtcaaggtg aagaggtaga acctgcacgt gttaaggcag
   167161 aagctgctgg tgtcaaagaa atttatattg aagatttacg tgaagagttt gcacgtaatt
   167221 ttgtatttcc tatgtttcgt gctaacgcta tttatgaagg tgagtattta ttaggtactt
   167281 ctattgctcg tccgcttatt tccaaacgct tagtagagat tgctaaacaa gtaggagcag
   167341 atgccattag tcatggtgca acaggaaagg gtaacgacca agttcgcttt gagttgaatg
   167401 cttatgcgtt gaatgcagat attcaagtga tagcaccatg gcgtgagtgg gatttatctt
   167461 cacgcgaaag tttgatggat tatgcccaaa aacatggcat tgaaattgat tacaaaaaac
   167521 aatctaaaaa atctccttat tcgatggatg ctaatttatt gcatatttct tatgaaggta
   167581 atattttaga agacccttgg acagaacctg aagaggatat gtggcgttgg acactctcac
   167641 ctgaaaatgc acctgataag gtagaatatg tcgaaatgac ttttaaaaaa ggagatatca
   167701 tagctattaa tggtaaagta atgagccctg cttctgtgat ggaagattta aataaacgcg
   167761 caggtgcgca tggtattggt cgtgatgata ttgtggaaaa tcgttttgtt ggtatgaaat
   167821 ctaggggttg ttatgaaaca ccttcaggta ctgttatgct aaaggcgcgt cgtgctatgg
   167881 aatcactcac gcttgatcgt gcagctgctc atctaaaaga tgagcttatg cctaaatatg
   167941 ctgaaatggt ttataatggt ttctggttcg cgcctgagcg tgaaatgtta caggctgcta
   168001 ttgataaaac ccaagaaact gttagtggtg ttgtccgtct taagttctat aaaggaaacg
   168061 ttactgttgt aggtcgtcaa tctaagaata gtttgtttag tgaaaaaatt gttacctttg
   168121 agaatgatga tggtatatat aatcaaagag atgctgctgg atttattaaa cttaatgcgc
   168181 tacgtttgtg tcttaataca ataaagtagc tcatattttt ttaattaaac ataatatttt
   168241 ttaaatactt aaatgtatag taaagagaat aagcgatgga ggctgggacc ggagtcgaac
   168301 cggtctataa ggctttgcag gcctctgcat aaccgctttg ctacccagcc atgttaaaaa
   168361 tctatattat tccttttttg gaagaatatg gtcttttaac ttggagcgga aaacgagatt
   168421 cgaactcgcg acattcacgt tggcaacgtg atgctctacc aactgagcta ttcccgcaat
   168481 aggtgataaa ttatagtgtt ttttaaataa tagtcaagtt agatacggca ttaattatta
   168541 aaagttttgt gctccttttt tcagataaat aaatccggac cataaagtta aaaaagttgc
   168601 tattaacaat aaagtaaccc ctattttaaa acttggtaac ccaaaaaaag attgttgata
   168661 caataaaaac aaaatagcaa atatttgcac aaaagttttc attttaccca tccaagaaac
   168721 attaatattc gatctttggc caatagttcc catccattct ctaagtgctg agattaaaat
   168781 ttcacgtgaa ataataataa gtgcacaaac actaatgtac caatgtgtat cagttgggta
   168841 gaaatctact agtagaatta gtgcagtgga gaccataagt ttatctgcaa ccgggtctaa
   168901 aaaagcacca agttgtgagg tcatatctaa ctttcttgct aagtatccat caaaataatc
   168961 tgttgcacta atgagtgcat aagtacttgt aagtaagaaa ttaatccaag taaaaacagg
   169021 tgttatagag taggtaggct gaaaataata taaacttaca aacactggaa ttagaaaaat
   169081 tcttgacaga gttagaatgt ttggaattgt gaccatggat tgattgttat gataagtatc
   169141 gaaaaaagat atggcgcgct cggcaggagt cgaacctgca accgatcggt tcgtagccga
   169201 ttactctatc cagttgagct acgagcgcat caagagcgtc attatctcta tatttgaatt
   169261 aaaggtcaag gtgaattaaa cttatttttt tagtaaatca accaacttat ttagttttgc
   169321 cattctagag ccttttatta atatagtagc gttagtatgg ttagtcagta tatggttagc
   169381 taatggttgt tttttttcga agtggatact acagtggtgt agtgctattt ttccatagct
   169441 ataaaaagta tcagcagatt ttttggctaa ttgtccaatt ttaaaatgga acatttttga
   169501 ataattgcct aattcttcca tagtaccgag tacaataatt ttttctccag aaaaattctg
   169561 taaagtttta agagcgataa tagttgagta tggattggcg ttgtaagtat cgtcaataat
   169621 tctaaattgt ttagtatgga taatttctaa cctaccaggt tctgcttttg ttgcttctaa
   169681 accttgcttg attaggttga tatcaattcc taatggatat acacaggcac tagctgctag
   169741 ggcattatca atattgtgta taccaatcaa gttaagtgtg attgatattt tttgctgatg
   169801 aatgtttaaa tcaaacttgt tattaacaat attactagca aaaatatcac cattattacc
   169861 acttacttta gtattcccat ggggggtaaa actaacatca cctgtaaaaa tgctttgagt
   169921 attaataata tttttagagt ttttcgaata aatttcaccc ttggctttga ctaaattatc
   169981 aaatccaccg aatgtaccaa tgtgtgcatc aagtgtatta gttacaatag caatatcagg
   170041 attaactatt ttacgaagat gtgaaatttc acctaaatgg ttagctccca tttcgatcac
   170101 tgcatattgg tgttgttttt ccaatgttaa taaagtcatt ggaacaccta agtggttatt
   170161 tagattacct tgagttttta atgttggggc ttgtaaactt agaatattag ctagcatatt
   170221 tttggtagta gttttaccat tactacctgt aatagcgata acaataggtt tgatattttg
   170281 gaggtgccaa ctagcaattg tactaagtgc agtttgtgta tcattcacta ctaatattgg
   170341 taactgacta tctacagatt tattagcaat gattgctact gcacccattt gttgtgcttg
   170401 atagatatag tcatgtgcat caaagttgtc gccaaccaaa gctataaata acgctccatc
   170461 catgcgtttt cgagtatcag tataaacgcc tttaaattta acattaacag agtaatctat
   170521 ttttaatact ttagcaatag tatttgtagt agtttgtagc ataaggttta tgattagttt
   170581 tcctattatt aaaatgtctt aaaagaaaca actaacatct attttaaaga ttttatattc
   170641 aatattttac gacaacttca gacatataga taattttgat agatttatat tccattttta
   170701 gtgtttatgt taattacgat atgttttttt gtatttggta ttgaattagc atttttttaa
   170761 atggttaaat atgccttatt aatgtttgta ttcaataaag aacttctata gtaaatagta
   170821 ctcaagtagt ctgtataatg tataaaatat ggtatttatg taaatataat aataggttgt
   170881 cttttctcta gaaaatgaat atagtatatt ttagcattta ggtttaatga aataaaatca
   170941 aacagtagta ttaacattat cggaataaac tttattttta aagtttaaaa aataattgta
   171001 tggtattcag ttagtataat tgaattattt gttctttaaa taatatagga atgtttttga
   171061 ttagaaatta agtatcttta atgctgtttt gtgcaatttg taaatcattt agatagatta
   171121 ttttattgaa taattgttgt gttgtttcat gtcctttacc agtaattatt aaacattcat
   171181 tttttttaag agttatcatt gcagtttcaa tggcaagttg tctatcttta ataatatcca
   171241 attcaaaact atcgtcaata ccatttagta tatcattgat aatggtttgt ggattttcag
   171301 atcttggatt gtcattggtt aagataatac tatctgctaa ttttgaagca attctaccca
   171361 tttttgaacg tttatttcta tccctattac caccacaacc aaagacaata cgaattttaa
   171421 agtttggata gtgtttttgc aaagttgtga tggcgttttc aagagcatta ggtgtatgag
   171481 cataatctat ccaagcatga tagtggttaa tttgttgcat tctgccaggt ggtgttgata
   171541 gttgataaat taatgggatt atatcgttgc gtttaaatcc aagtgcttca acactgttta
   171601 atgttgctag aatatttagt aaattgaatt cacctaaaaa tggaatttca aaaacataat
   171661 gatctaattg tactaagaag ccttgttgaa tgattttaat tgaattaaaa tcattcagag
   171721 aataactagt ttgctttttc cctttgctaa cttttaggaa gtgtttataa tgatgatcat
   171781 cttgattgag aataacagat ttgacacaat taagggtgaa taacctctgt ttggttgttt
   171841 tatattcatc aagcgtgtga tgataatcaa gatgatcttg agtaagatta gtaaatactg
   171901 cttgtttaat attaagtcca gcaatcctat tttgagcaag tgcatgtgaa gatatttcaa
   171961 ttacagcata gtgaatgtct tgttgataat aatgatgtaa tactcggtat agtgttaaaa
   172021 tatctggagt tgtattaaag taaagttgtt tattatgggt aattcctaaa gtaccaatta
   172081 aaccattttt gacccctaat ttctccaaaa gctgtgaaat aaggtatgta acagaagttt
   172141 taccatttgt acctgtaacg ccaatcacat caatttttgt agcgttatta taaaaagtgt
   172201 ttgccagtgt ttgtaaatat ataggtaagt tattaacacg aatagatgga atagcacatt
   172261 ctatctcttt tgagtcaact aatatagcaa cacaaccctt gtcaatcgct tggtttatgt
   172321 aatcggtacc gtttgttgac tctccttgaa gagcaataaa taaatctcca ggttgtgcac
   172381 tttgagtatt aagacataga ccttttattt ctatgtctac ttcagtttgt ataatgttga
   172441 tcaaaagttg agaaatattc atatatttag tattataaga ttttttctga ttctttaata
   172501 aaaatgttat tatttattag tgtatcttca taggtgaata aatctgttaa aattttgatt
   172561 atcttatcta attaaataat ttttttgggg agagtatggc gttaacacgt agagatttta
   172621 ttaaagtatt aggtgctggt tcagcggtag ggttgattag tggttgtggc aatgatacag
   172681 acaagttatc ttctcaagac aatcgatacg aggtagcaaa aacaggtaat gctcgtattt
   172741 tgcatattac cgatactcat ggtaacttgc ttcctaatta ttttcgtgag cctaatgtta
   172801 atctaggttt tggccctact tttgggcaat taccacatgt ggtaggtaat aatttactta
   172861 agcagattgg tgttaaagca ggttcagctg atgcttatgc ttttacttat aataattttg
   172921 aagatttagc agcaaaatac ggtaaaaccg gtggttttgg tcaaattaaa actgtattag
   172981 attcattaag agaaagtgca ggtggtgtac aaaatacact gaccttagat ggtggtgata
   173041 cttggcaagg ttcaggtacg tcactttgga cgcgtggtgc tgatatggtt gaagcttgta
   173101 atattttagg agtagatgtc atggttggtc attgggaatt tacttataaa gaagaagaaa
   173161 cattaaagaa tattaacttt tttaaaggta actttttagg tcaaaatatt cgtattgtag
   173221 aagatgcatt aatgggagat agttatgtca ctatgactga acgatatgat ggaaatggtt
   173281 tatttaatga agaagatgct ttgccattta gatcttatgt gattaaaaat gtgggtggta
   173341 atcgtattgc tgtgattggt caagcctttc caaggacttc aaatgctaat ccgaaaaaat
   173401 atttttttcc agactggtct tttggtttgc gcgaagatga gatgaatgag ttagttactg
   173461 atattcgtaa aaataaaaaa ccagatgcta ttattgtgat ttcgcataat ggcatggatg
   173521 ttgatattaa aatggcatca cgtattagcg gtattgatgc aattttcggc ggtcatacgc
   173581 atgatggtat acctaagcca gttgaagtaa acaacgcagg tggtgttact gtggtaacta
   173641 atgctggttg ttcaggtaaa tatgttggcg taatggattt aaatattaaa gatcataaag
   173701 ttatgggcta tgaatataaa atgctaccta ttttgactaa ctttattaag cctgatgtga
   173761 gtatgatgtc gtttattaat caaatgcgta ctactaaata tgataagaac gtagttgaag
   173821 ctcgtagtga taaaatgtca aacaaccttg atcgtatcgg taagacttac gatgcaattt
   173881 tgacagaaaa attatgtact actgagcaaa cactttatcg tcgtggtaac tttatgggaa
   173941 cttgggatca agttctagtt aattcgctac gtgaagaata taatgcggat ttttcaatgt
   174001 cagcaggtgt gcgctggggt acaagcgttc cagcagggca tgatgtgacc atggaagatt
   174061 tgatgactaa cacctcaatg acttatggtg aaacttacgt gaatgagatg aaaggttctc
   174121 aactgaaaga aattttggaa ggtattgcag ataatttatt tgtacaagat ccatatttac
   174181 agtcaggggg tgatatggtg cgtatggggg gtatggatta tacaattgat ccagtagcaa
   174241 gttttggtaa gcgtattagt aacatgaaag atgatgaagg aatagctatt gatcaaaata
   174301 aatcttatag agtatcagga tgggcgcaag ttgatagtgt tggtaatggt cgtttaatgt
   174361 gggatgtagc agcagattat ttacgcaaac agaagcatct taatttaact aaaataaatc
   174421 atccaactat taagggtgtg aacaataatc caggtattga aaactatggt ggtaaactaa
   174481 tttaaatttt ttaataaaaa ttattttgat tgtaatgtgt tagataatct aaaagatacc
   174541 attaagaatc tttggtttct aaatctagga gaggaagcta tatacattaa taataatgtt
   174601 gttcgtgttc gtgttcgtgt tcgtgctagt attttactta ttgttccaac ttatataatt
   174661 ttcacctttt ggaatgatcg tattatttat taagtagagg caataaacct gaatggaatt
   174721 ctattggtct aaaacgttgt gcttgtatat tgggagtgat ctttatctct gtatgtattg
   174781 ttttttaatc cagatatagt cgcactttgg attaatggtt tattaggtac tggtattctt
   174841 attgataaaa attatgtatc ttcttggttg gtattgaatt tggtgtagat atgtttatta
   174901 tttatgaagc ttgtgaaaat attgatcgta gtgacttaag aaataataac ttgtttagat
   174961 aagcaaaata aatgctatat tgtatgttgg tttgcatgtt aacaatagat gtagttaagc
   175021 tttttatagg aaaatcaatc tattctaata aaaaagtaaa agttacaatt gattcaagtt
   175081 tttaatctat gattgatgtt caacataaaa taatacactt atattaggag gagtaattaa
   175141 gctgattttt taagttatat tctgccatgt tctattgatt tttaatggaa aattagtatt
   175201 taaacctatt taaggaaaaa ttaatattgt ggtctataag atatctctat taatttattc
   175261 aactaagttg aataaatgat taaaaacctt atcctggtag tataatagtg cattgcgttg
   175321 aacttataac ttgataaata taaaaatgtt ataccattag attacgatca tattttattt
   175381 attagtatgc gttacttagt taacacaaat tatgtattgt taactttatt ttttataaaa
   175441 tcattaaata tggattataa aaaatagtta ttgttctaat tttagtactc atttctttca
   175501 ttgaagtttg gtggggtata gagtgattcg cgggttaaat aatttttgct tgcattagag
   175561 tgtgggtatt aatagcacca aggatttggt tattatcatc aactacgggt aatgagttta
   175621 gattaaattt atccatcatt tgtactgctg ctatagcggg tttatctgct gaaattgatt
   175681 ggcaattatg tgtcataact tcgccaatag ttaaggtttg aatattggga tgtgtttcaa
   175741 ggactcgcct taaatcgcca tccgtaaaaa taccttttag ggtattatta tcggtaatta
   175801 ataccatacc taaggttttt tgactcatta ctaataaagc atttagtaat ttaatatcag
   175861 cactaaccat aggtatatca ttacctgttt tcataatggt actaacaaaa gttaacagac
   175921 gacgacctaa tgcgcctgat ggatgtgatc gtgcaaaatc atccacacta aaacctttat
   175981 tagttaacaa actaattgct aatgcatctc ccatgactaa ggctactgta gttgaagagg
   176041 ttggggctag gttatgtgga caagcttctt tttcaacatt tacatcaaga tgcacgtcgc
   176101 taattttact aattgaggaa tttacatttc ctgtcatgcc tatgatgaac acaccaaggt
   176161 gtttaataat tggtattaag gtcataattt cgtcagattc accagaataa gaaatggtaa
   176221 tcacaacatc ttcttgtgta atcattccta aatctccatg tcctgcttca ccaggatgaa
   176281 cagcaaaagc gggtgtgcct gtggaggcaa gtgttgctgc aattttactt gcaatgtgtc
   176341 cagatttacc catgccaatt aataccactt tcccagtaca attttgaatt aattggcaag
   176401 catcaataaa gttttgatca agactatcag ctaacattgt tacggctttg gcttcagtta
   176461 aaattacatt ttttgcagat tgtaataatg agttagacat ggttaataaa tacattgata
   176521 taatatatca ctgattttat caatacatat gacgtgttag taaagagaaa ataaatttta
   176581 tttgtatgta tgtataatat ttttcgcttg ccaatgtaag tttttttaga ttataagtgg
   176641 agaaatgcta tgttgagtgt ttgtttgaag tagatttttc tgatgtttat tcttattata
   176701 ttagtgagta attagattct ctaaaaatta gtcgttgata aatatcatgt taattgatct
   176761 aatcaacgag tacgataagt atatgattag tggtttttta ttaaaaaagt ttgttaaaca
   176821 atctccgtaa atcttgttga catagttact tctaacaaag tataatgcct ggctttgttg
   176881 tctttaagaa aaatcataaa gacgatacaa tagcttaaat acaattataa actttagaga
   176941 aatttggagg aattgcaaca tgtcaacaat taatcaattg gtacgtaatc cgcgtaaaaa
   177001 gaaagttatt aaaagtgggg ttccagcatt agatagttgt cctcaaaaac gcggtgtttg
   177061 tactcgtgta tatacgacaa ctcctaaaaa gcctaattca gcacttagga aagtcgctcg
   177121 tgttagatta actaacgcta atgaagtaac gacctatatt ggcggtgagg gtcataattt
   177181 acaagaacat tcggtgattc ttattcgtgg gggtcgtgtg aaagatttac ctggtgttcg
   177241 ttatcacaca gttcgtggtg cattagatac aacaggtgtt gatagtagaa tgcaaggtcg
   177301 ctctaaatat ggcactaaga agccaaaaaa ataagtaatt acaataatta aaataagaga
   177361 aataaaatga gaagaagatc tgcacctaaa agagaaattc taccagaccc taaatttggc
   177421 gatttggtat tggctaagtt tattaatatt ttaatgtttg atggtaagaa atcagtggca
   177481 gaaaaaattg tatatgaagc tttagatacc attaaagcta agggtaatgc gcaaccaatt
   177541 gaagtattta agcaagcatt agataagatt ggtcctcaag ttgaaattaa atctcgtcgt
   177601 gttggaggtt ctacttacca agtgccaatt gaagtgagaa ctgaacgtaa gagtgcttta
   177661 gcaatgcgtt ggattattga agcatcacgt aagcgcggtg caaaaagtat gaagcttaga
   177721 ttagcaggtg aaattttaga tgctatacaa aatcgtggta atgcatttaa aaagaaagaa
   177781 gattctcata gaatggcaga agcaaataaa gcatttgctc attttcgctg gtagtaatat
   177841 acataggaca caagaagaat ggcaagaaca accccacttg atcgttatcg taatgttggt
   177901 attatggctc atattgatgc tggtaagaca accactacag aacgcatttt gttatatact
   177961 ggccgtactc atagaattgg tgaagtgcat gatggtagtg caactatgga ttggatggaa
   178021 caagagcaag agcgtggtat tactattact tctgcggcaa ctacttgttt ttggaaaggt
   178081 atggatggtc aatttgagga tcatcgtgtg aatattattg atactccagg acatgttgat
   178141 tttactattg aggttgaacg ctcattaaaa gtattagata gtgcttgtgc tgtattttgt
   178201 gcagttggtg gcgtagaacc tcagtcagaa acagtttggc gtcaagccaa taaatacaac
   178261 gtaccaagaa ttggttttgt taataaaatg gatcgttctg gtgcggattt tttacgtgtt
   178321 tgtaaacaaa ttaaaacacg tttaggtggt aatccagtac caatgcaaat tgcaattggc
   178381 gcagaagaaa gttttgaagg tgtgatagat ttaatcagta tgaaagctat tttttggaat
   178441 gaagttgatc aaggtgcaac ttatgaaaca agagatattc ctatagagct acaaggttta
   178501 gcaaaagaac aatatgaatt tatggttgaa tctgctgctg aggcgaatga tgagttgatg
   178561 gaaaaatatc ttgaagagag taagcttagt aatcatgata ttaaaaaagg tattcgttta
   178621 cgagctataa aaagtgaaat tattccaatg ttttgtggtt ctgcttttaa gaataagggc
   178681 gtacaagctg tgttagatgc tatgattatg tatatgccat caccattaga tgtggatgct
   178741 ataacaggta tatcagatga caaagatgag acagtcgttc ctagaaaagc cgatgataat
   178801 gaaccttttg ctgcattagc atttaagatt gctactgatc catttgtggg taacttaact
   178861 ttttttcgcg tatattcagg cgtattagaa gcaggtgatt ttgtatacaa ttcatctaaa
   178921 ggaaaaaaag aacgtattgg tcgtatggtg caaatgcatt ccaacgagcg tgatgaaatt
   178981 aaagaggtac gtgcaggtga tattgcagca gcaattggtc ttaaagatgt aacgacaggc
   179041 gataccttgt gtgatatgaa agaaaaaatt atacttgaaa gaatggaatt tcctgagccg
   179101 gttattgcat tagcagtgga gcctaaaact aaagcagatc aagaaaaaat gggtattgct
   179161 cttggtaaat tagctgctga agatccttct tttcgtgtgt caactgatga agaatcaggt
   179221 caaactatta ttgcaggtat gggtgagctt catttagata ttattgttga tcgtatggtt
   179281 cgtgaatttg atgttgaatg taatgttggt gcaccacaag tttcttatcg tgaagctatt
   179341 acaactatgg ttgaacatca gcataaattc gtcaagcaat ctggtggtcg gggtcaatat
   179401 ggtcatgtgt atttacggat tgaaccgcaa gaaccaggta ctggttatga atttgtagat
   179461 gaaattaaag gtggtgttat tcctaaagag tatatgcctg cggtaaacaa aggtgttcaa
   179521 gaacaaatgg aaaatggtgt attggctggt tttcctttag ttgatattaa agtaaccgtt
   179581 tatgatggtt cttatcatga tgttgattca aatgaaattg catttaaaat tgcagccagc
   179641 aagtgtctaa gtgaaggtgt taagatggct aaccctcaat tacttgagcc tatgatggca
   179701 gtggaggtgt taacacctga agactatatg ggcgatgtaa tgggtgatat taatagacgt
   179761 cgtggtattg ttagtgcgat ggaggatatg cctgcaggta agcaagtcaa ggcagaagtg
   179821 ccactagcgg aaatgtttgg ctattctaat gatttacgct caattacaca aggtcgagca
   179881 aattattcca tggaatttgc aaaatataca gcagcaccaa aaaatgtagc tgatgaaata
   179941 attgaaaaat taaacaagta aggaacatac aatgtcaaaa gaaaaattcg aacgaaccaa
   180001 accacatgtc aatgttggca cgattggtca tgttgatcat ggtaaaacta cacttacagc
   180061 tgccataact aaagtgatgg cagaagttcg tggtggagaa ttcaaagatt atgcagatat
   180121 tgataatgct cctgaagaaa gagaacgtgg tattaccatt tcaacagctc acgtagaata
   180181 tgaaagtgag atacgtcatt acgcgcatgt tgactgtcca ggacatgctg attatattaa
   180241 aaacatgatt acaggtgctg cccaaatgga tggagctatt attgtaattg ctgctacaga
   180301 tggtccaatg gctcaaaccc gtgagcatat tttgttatct aaacaagtag gcgtgcctta
   180361 tatcgttgtt tatatgaata aagctgatat ggttgatgat gaagaattag ttgaattagt
   180421 tgaaatggaa attcgtgagc tattggatga atatgacttt ccaggtgatg acactccagt
   180481 tatttttggt tcagcactta aagccttaga aggtgatatt tcagacattg gtgttccttc
   180541 tatcttaaag ctagttgacg cattagactc ttatatccca actcctaagc gtgatacgga
   180601 caaatccttc attatgccaa ttgaggatgt attttcaatt tcaggtcgtg gtactgtggt
   180661 aacaggtcgt attgaagcag gtgttgttaa tattggtgac gagttagaaa ttgttggtat
   180721 taaagatact aaaaccacta cttgtactgg tgttgagatg tttagaaaat tactttcttc
   180781 aggtgaagct ggtgataacg ttggtgtttt acttcgtggt acaaaacgtg aggaagttga
   180841 acgtggtcaa gtattatcta agccagggtc aatcaaacca cacgcaaagt ttgaagcaga
   180901 aatttatatt ttaagtaaag atgaaggtgg tcgtcataca ccatttttta acaattatcg
   180961 tccacagttc tattttagaa ctacagatgt tacaggtgct tgtcagttgc ctgatggtat
   181021 agagatggtt atgccaggtg ataatgtgaa aatgagagta gagctattat caccaatagc
   181081 tatggaagat ggtttaagat ttgctattag agaaggaggt cgtacggtag gtgcaggtgt
   181141 agtttctaaa gtgacggatt aagttaatta gagcagtaag atttattgta taatcttacg
   181201 ttttttattt gagaaattta caacgtaaat agacaggata taaagataca tgagcaatca
   181261 aaatattaga attaaattaa aagcatttga tcatcgttta atcgataaat cagcggttga
   181321 aattgtagaa acagctaagc gtacaggagc cagtgttaga ggtcctattc ctttgcctac
   181381 taagaaggaa cgtttcactg tattgacttc tcctcatgtt aataagaaag caagagatca
   181441 atacgaatta agaacctacg ttaggttaat ggatgttatt agcccaacag acaagacagt
   181501 agatgcgtta atgaagttag atttagcagc aggtgttgat gttgcaatta agcttaatta
   181561 agcaattaca taatttagga ataaaaatca tggcaatcga tttagtagga caaaaaatag
   181621 gaatgacacg cttgataagc gatgatggtt ctattatgcc agtgagtgtg attaaaattg
   181681 aacccaatcg tattgttcaa acaagaacga ttgatataga tggttatagg gctattcaag
   181741 taacaacagg aaaaaaagta aataaaaaag gcgaagctaa agtgcgtcgt atttctgctg
   181801 cgattaaagg tcattacgct aaagcttctc aagaaattgg cttaggactt tgggagttta
   181861 aactggaaga taatgaaata actaacgcaa caagtattga tatttcgtta tttggagctg
   181921 gtcattatgt tgatgttata ggtaaatcta aaggtaaagg gttccagggt ggtgtaaagc
   181981 ttcataattt ccaaatgcaa gatgctactc atggtaattc aatttctcac cgtgctattg
   182041 gttctacagg acaatgtcag gaaccaggtc gtgtatttaa aggtaagaaa atggctggcc
   182101 atatgggtaa taagcaagta acacaagaat gtcttaaggt tgttaaagta gacattgaga
   182161 aaagcgttat tcttgttaaa ggatcaattc ctggagcgat taagggtttt gttaaggttt
   182221 ccttgtcacc taagaaagat aatagtaata aagaagttag caaaaatatt aaaaatcaag
   182281 taactaatga agttgaccag actaagcaaa tgtaagtaag ggtttaagat ggaattaaaa
   182341 gtattaaata taagtttaaa tagtttaaac accgttgagg tggatgatac tatttttgca
   182401 agagatttta accaagcatt ggtccatcaa gtgactacag cttatatgtc tggatctcgt
   182461 caaggttcta aggcacaaaa aaatcgttct gctgttagtg gtggcggtaa gaggccttgg
   182521 gcgcaaaaag gtacaggtcg tgcccgtgct ggtactactc gtggtcctat ttggcgttca
   182581 ggtggtgtta cgtttgctac acaaccaaga agttatgcac aaaaagtgaa taagaaaatg
   182641 tataagggtg caattagtat tattttttct gaactcgttc gttctgaacg cttaaaagta
   182701 gtaaaagaat ttgatattaa agaagttaaa actaaaaata tgatcgcatt acttaaagta
   182761 cttaacgtta aagatgcttt attgatgact gatgagttag atgagaatct atatttatct
   182821 tctcgtaatt tataccatgt tggtgtttgt gatacacaaa gtattgaccc agttagctta
   182881 attggttatg ataatgttgt ggtaactgag ctggcgttga aaaaaattga ggtaatgtta
   182941 tgaatcaaga aaaggtatta aaaaccttat taatgcccat cgtttctgag aaaatgacta
   183001 tgctatcagc gaataatcaa tacgcattta aggttcgtat ggatagttct aaaagagaaa
   183061 ttaaagctgc agttgaaata ttattggggg tgaatgttga aaatgtgaca actttaattg
   183121 ttaaaggtaa gaaaaaaata tttaaaggca ggactgggtc gcgtccaaat tggaaaaagg
   183181 caatggtaaa agtgtctgca ggccaaataa ttgatgtgaa tagaacttaa agagattatt
   183241 atggcacaag taattaaaag aaaacctacc tcacctggta gaagatttgt tgttagtatt
   183301 gtagataaag agttacataa aggtacatct tatggaccat taacgcagaa taaaaataga
   183361 attaatggtc gtaataacgc aggtcgtatt actatgcgac ataaaggggg ggggcataag
   183421 cgtcgttatc gtattattga ctttaagcgt aataaagatg atattactgc acgtgttgaa
   183481 cgtttagaat atgacccaaa tcgtagtgct aatattgcct tgattttata tgctgatggc
   183541 aaacgccatt atattatagc acctcgtggt ttaagtgttg gtgatatgat tgtgtcaggt
   183601 aattctgtcg ccatccaagt aggtaatgtt atgccattaa gtaatatacc attaggtagt
   183661 atagttcatt gtattgaatt aagacctatg aaaggtgcgc aaattgctcg tagtgccggc
   183721 acttctgcac agttgattgc taaaagaggc acttatgtta ctttaagact tcgctctggt
   183781 gaggtacgta aggttttgac agattgtcgt gcaactattg gtgaggtttc taggtctgaa
   183841 catagtctaa gaaaattagg taaagcgggt gctactcgtt ggcatggtgt tcgtccaact
   183901 gttcgtggcg ttgttatgaa ttcagttgat catccacatg gtggtggtga aggtaaaacc
   183961 agtggtggta ggcatccagt ttctccttgg ggtaccccta ctaagggtta taagacacgt
   184021 agtaataaac gcacagataa gcttatcttg cgtcatagaa ataagggtta attatatggc
   184081 tagatcatta agaaaaggac catttgtaga tgagcactta attaaaaagg tattagcggc
   184141 tcaaggtaat aatgacagaa aaccaattaa aacatggtct cgtcgtagtg ttgtcgtgcc
   184201 tgaaatgatt ggacttacta ttgcagttca taatggtaga gtacatgttc ctgtgtctat
   184261 caatgaaaat atggttggtc ataagttagg cgaatttgcc attactagaa ctttcaaagg
   184321 tcactttggt gatcgcaaag cttaaataaa tataggtagg tgatgatgaa agaagttaaa
   184381 gcagtgcata aatatgcaaa aacatccgct tttaaagcaa gattagttgc agatcaaatt
   184441 cgtcttaaat cggtagaaga ggcattaaat attttatcat ttagcaataa aaaagccgca
   184501 gtcttagtta aaaaagtact gaattcagtt atttctaatg ctgagcataa tgatggacta
   184561 gacattgatg aattatttgt cactagtatt tatattgatg aaggttcaac catgaaaaga
   184621 attcgtccaa gagcaaaagg aagggcaaat aggattttaa aaagaacaag ccacattaca
   184681 gttggcatag gcaagtaggt ttagtatggg tcaaaaagta aatccaaaag gtattagatt
   184741 aggtattatt aaggattggg attctaaatg gtacgctagt tctaaagatt attctaagta
   184801 cttattatct gatattaaag ttagaaacta tctatttaag aaattaataa atgcttctgt
   184861 tagccgtgtc cagattggac gtttggtgaa taatgctaaa gttactattt atactgcacg
   184921 tccaggtatt gttattggta agaaaggtgc tgatattgag cagttaaagt taattgtttc
   184981 aaaaatgatg ggtattcctg ttcatattaa tattgaagaa attaaaaaac ctgagcttga
   185041 tgcacgtttg gtggctgaga atattgctca acagttagaa aaacgtgtga tgtatcgtcg
   185101 tgctgttaag cgtgtgctag gtaacgcaac tcgtttaggt gctcaaggta ttaaggttat
   185161 ggttagtggt cgtttaaatg gtgcagaaat tgcacgttct gagtggtatc gtgaaggtcg
   185221 agtaccatta catactttta gagctgatgt tgattattct tcttatggtg caaaaacaca
   185281 gtatggtgtt attggtatta aggtttggat ttttaagggt gaaattttag atcataaaaa
   185341 aggcacacta gatgaggttg ctcatcgtgg tgcaataaat caaattgcta aaaaataaag
   185401 tgaaggattg ataaatgtta caacctaaga gaacaaaatt tagaaaaatg atgaaaggcc
   185461 gtaatcgtgg tcttgcaacg ggtcataagg ttagttttgg tgaaattgga ctccaagctg
   185521 tgggtagatg tcgtttgtct gctagacaga ttgaatctgc acgtcgtgca atgacacgtc
   185581 atgttaaacg tcaaggaaaa atttggattc gtgtgtttcc agataagcct gttactaaga
   185641 aaccattaga ggttaggatg ggtaaaggta agggtagtgt tgaatattgg gttgcaaaga
   185701 ttaagcctgg tcaaatgtta tttgaaatgc aaggcgttga agaaacagtt gctatagagg
   185761 catttgcgtt agcatcaggt aaattaccag ttaaaacaac aattattaaa cggacggtaa
   185821 tgtaatggat gttaaagaat taagaaatca atcagtttca gcgcttaatg aaatgttgat
   185881 taaacttcta aaagaacatt ttgagtttcg tatgcaacac aaaagttcac aattggataa
   185941 tttttcgaag ttgggaaaaa caaagaaatc aattgcacaa attaaaacta ttattaggca
   186001 aaaacaagca tgaatgaaaa aaaagtagaa tgcgtattaa caggaactgt tgtaagtagt
   186061 aatcgtgaca aaactattac tgttttaatt gagcgtaaag taagacatcc tatttacaaa
   186121 aaatatatta aacgtagtac taaagtacat gcacatgacg ataagaatga atgtatatgt
   186181 ggtgatttag ttcgagtagt tgaagcaaag ccattttcaa aaactaagca ttggtcatta
   186241 ttagaagtgg ttgagagatt agtttctgtt gattaatatt aaatttattt aaagagagta
   186301 agtcatgatt caagtacaaa caagacttaa ggtcgcagat aatagtggtg gcattaaagc
   186361 aatgtgtatt aaggtattgg gtggttctaa gcgtcgttat gctaatattg gcgatgtcat
   186421 taaagttagt attaaagagg ttgtaccacg tggtaaagtt aaaaaaggtg atgtttatga
   186481 tgcggttgtt gtgcgtactg ctcatggtgt tcgccgtagt gatgggtctc gtattcgttt
   186541 tgatagcaat gcgattgtac ttttaaatac aaaacgtgaa ccaattggta ctcgtatttt
   186601 tggcccagtg acccgtgaat tgcgtagtgc acaatttatg aaaattgtct cacttgcacc
   186661 agaggtttta taatgcaaaa gattaaatca aacgatgaaa ttattattat tgctggcaag
   186721 gataaaggtt ctataggtat agttactaag attgtggatt ctaaggttct ggttgaaggg
   186781 ttaaatcttg ctaagaaaca tgtgaagcct aatccaaata agggcgtcac aggtggtatc
   186841 acagagatag aaatgccttt atcgatttct aatgttgcta tttataatcc aacaactaag
   186901 aaagctgata gagtgggaat tcgtactagt aaaaatggta ttaaagaaag attttttaaa
   186961 tcaaatgata aatcaataat ttgataaggt ataagatata aggaaatata agtatgtcta
   187021 gattacaaga gcaatacaag aataaaattt cactaatttt acaaaaagag ttaggtatgt
   187081 ctaatcctat gcaaacacct aagattgaaa agatcacaat caatatggga ctaggtaatg
   187141 cgttaggtga taaaaaaata ttgcaaagtg gtttagaaga aatgagtctt atttctggtc
   187201 agaaaccact aacttgtaat gcacgtaaat cagtagcaag ttttaaatta agagagggaa
   187261 atccaattgg ttgtaaagtt actttacgta agcaaaagat gtatgaattt cttgatcgtt
   187321 tagttaatat taccattcct cgtattcgag attttcgtgg tttaaaaact actgcatttg
   187381 atggtcgtgg taactacaat atgggtatta ctgaacaaat tacgtttcct gaaattgatt
   187441 ttgaaaaagt aacaaaaata cgtgggatgg atattgctat taccacaact gcaaaaagtg
   187501 atgaagatgc taaaaaacta ttagcaatgt ttaaatttcc atttaaaggg taagaaaaat
   187561 ggctaaaaag tctatgatga atagagacat taagcgcaca aagatagtga aaaaatataa
   187621 agcaaaacgt cttgagctta agaaaattat taagagtatt aacgtatctg atgaagaacg
   187681 tttccaagca actattaagt tgcaagctct tccacgtaat gcttcgccca cacgtcaacg
   187741 tagccgttgt agtttaactg gtcgtccgca tggattttat cgtaagtttg gtcttgctag
   187801 aaataaactt agagaatgca ccatgaatgg tgaagttcca ggtttatcta aagctagctg
   187861 gtaaggagaa ataatatgag tatgtctgat cctattgctg atatgttaac acgtattcgc
   187921 aacgcacaac tagttaagaa aaaagaagtt aatgttccat catcaaattt aaaatttgct
   187981 attgcaggtg tgatgcaaca agagggctat attgaatctt ttagtgttaa tggtgttgtt
   188041 gctagtaaaa tattaaaaat caagttaaaa tattatgata ataagccagt cattgaaaaa
   188101 ttgaagcgta tatcaaagcc gagcctaaga gtttatgtta gtaattcaaa aattccaagt
   188161 gtaatgaatg gattaggtat tgttattgtt tctacaccta aaggtgtgat gactggacaa
   188221 gtggcgcttg atcaaaatgt tggtggcgaa gtgttgtgta gcatttatta atattggaga
   188281 attagaatgt ctagagttgc aaaatcatca attactatac caactagtgt tgaagttatt
   188341 attactggta atttaatgtc tgttaaaggt agattaggcc agttaaacat gagtattcat
   188401 ccttgtgtgg caattatgaa tactaatagt aaacttagtt ttgatattat taccattgaa
   188461 aagaaagaac aaaggaaagc ttgggctcag gctggtacag caagggctaa tactgcgaat
   188521 cttattcaag gtgtaacaga gggttggaaa aaaaagttaa ctttgattgg tgttggttat
   188581 cgtgctaaag taatgggtaa aatattggat cttacattgg gtttctcaca tccaattaat
   188641 tacaaatttc cagaaggcat tatagttgaa actccttctc aaactgaaat tattattaaa
   188701 ggtatggaca agcagaaagt aggtcaagtg gcttcagaaa ttagatctta tcgtccacca
   188761 gagccttata aaggtaaggg tgttcgttat attgatgaac aagttattca caaagaaact
   188821 aagaagaaat aattgactaa ggtattaata tgaaattttt aaaaaaacaa gctcgtttaa
   188881 gaagagcaac taaatttaga gccaagcatg cgaaaaaaga tattgagcgc ttgtgtattc
   188941 ataaaactgc acagcatatt tatgctcaga ttattagttc ttgtggtact aaaattttgg
   189001 cttctgcttc aacattaaaa gctaagctta aaaatggtgg aaatgtagat gcggcagtta
   189061 aggttggtga ggcaattgct aaagctgcta ctagtgtaaa agtaaaaaaa gtagcttttg
   189121 atcggtccgg atttaaatat catggtcgtg ttaaagcatt ggctgatgca gcaagagaag
   189181 gtggtttgga cttctaagtt attaataaaa ttaattaaaa aaataataag gcgtagataa
   189241 tggctggata taaggaaaat aataatattg ataataacta tattgaaaag ttagttaata
   189301 ttcgtcgtgt tgtaaaagta gttaaaggcg gtcgtatatt tggtttttca gcattagttg
   189361 ttgttggtga tggtaatggt aaagttggct atggaacagg aaaagctcgt gaagttcctg
   189421 ttgctattca aaaagcaatg gataaagctc gtaaggcaat gaagaatgtt ccactagtaa
   189481 atggcacact tcattattca attatctcaa atgttggtgc ggctaaagtt tatatgcaac
   189541 cagcttcaga gggtacaggt gtaattgctg gtggtccaat gcgtagtgta ttggaagcag
   189601 ttggtgtaca taatatcttg gcgaaatgta atggtactcg taatccaatt agtgtggtac
   189661 gtgcaactgt tgagggttta acttctatgt tatccccaca attagttgct actaagcgtg
   189721 gtatgactgt tgatcaaatt actggagagg aataatggcc aaagaaaata gaacagttaa
   189781 aaaagtaaca actatccaaa agacgcaagt atctagtaag cacaacacag ttagtgttac
   189841 cttagttaaa agttttcatg gtcgcttacc atcccatcgt gaaaccattg taggacttgg
   189901 tttaaaacgc attaaccata caaaaaagtt taaagatact tctgaaatta gaggtatgat
   189961 taataaagta tcttacttac taaaagtaga gaattaggaa aatgaattta atgcaattaa
   190021 atacattatc acctgcacaa ggtgaaaaga aatcaagaaa acgcgtgggt cgtggtattg
   190081 gtagtggtat tggtaaaact tgtggtagtg gtcataaggg tcaaaaatca cgttctggtg
   190141 gtttcaataa gattggtttt gagggtggtc aaatgccttt gcaacgtcgc cttcctaagg
   190201 ttggattttc atcaagaata tctattatca cctctcaagt aacactatct gaaattaata
   190261 gattaactga gacttacatt actattgatg ttttcaaagc gcataattta attactaaaa
   190321 atattaagcg tgtcaaagtt atactttctg gtgaaataac tagagcagtt acattgactg
   190381 gcattaaagt aactaaaggt gcaaagttag ctattgaagc tgttaaaggt tcagtgagcg
   190441 attaagtgat gaaccaacct ttaaaccttt ctcaagattt atcaaagcgt atactttttt
   190501 tattgggcgc gttaattatt tttaggttgg gcacgcatat tactattcca tttatttcaa
   190561 gtatagcatt agcttctctc gtacaaaatc agcaaggcac tattttagat atgttcaata
   190621 tgttttcagg tggtgcatta gagagattgt ctatttttac tttaggtatt atgccttata
   190681 tttcgtcatc gattattatt cagttgatga cctctgttgt gccaaaatta gagcaattaa
   190741 agaaagaagg cgaaacaggt aaacgtagaa ttacacaata tacacgtata ggtacagtga
   190801 tattagcggt atttcaatct tatggtattt ctattgcttt acaatcacaa agttctggtg
   190861 gtgttacttt agtgactcaa agcggtttta cttttagtat ggttactgtt gtaacattaa
   190921 ctacaggaac tttatttcta atgtggttag gtgaacaaat tacagagaaa ggcattggta
   190981 atggcatttc aatgattatt tttgctggta ttgtttcagg cttaccttcg gcatttggtt
   191041 caactttatc gttagtatct acaggtgagt taagtattat tttggtagta attttattaa
   191101 ttatgacatc actagtgata gcttttgtgg tctttatgga gcgaggccaa cgtcgtatta
   191161 cagttaatta tgctaaacgt cagcgaggtc gtaaaatgat tggcgctcag agttcatatt
   191221 taccattaaa aattaatatg gctggtgtca ttccaccaat tttcgcttca tcaattattt
   191281 tatttccagc aacattagga ggctggtttt cgagaagtga aggtatgggt tggttggcag
   191341 atataactga aagtatatct ccaggacaac ctttatatgt tttattttat ggattggcta
   191401 ttgtgttttt tacttttttt tatactgcat taacatttga ttcaaaagat acagctgata
   191461 atttacgtaa gtcaggtggt tttattccag gtattcgacc aggtaaacac tcagcagatt
   191521 atattgattc agttatgtct aggctaacag cctctggtgc ggtttatatt acggctgttt
   191581 gtttgttgcc agagttttta attttatact ggaatgtgcc attttacttt ggtggtacta
   191641 gtttattaat catcgttgtt gtggtgatgg actttattgc acaagcccaa tctcatttga
   191701 tgtctaatca gtatggatca ttaatgaaga aggcgggttt aaattaaaaa aggtaattat
   191761 tatgaaggta agagcatcag ttaagagaat ttgtaacaat tgtaaaatta ttaagcgtca
   191821 tggagttgtt cgtgttattt gtaaagaacc ccgtcataag caaagacaag gttaattaga
   191881 gttgatattg aaaaactgta agagtagaat aatgggtttt ttaaatttgg tattgaacgt
   191941 tgctacaata aaaattatat aataatagat taaaatttaa agatataagg aaaataagct
   192001 tatgagacag atatgcgtta gaggtataag atagatggct agaatagcag gaataaatat
   192061 tccaacacat aaacatattg tgattggctt acagtcaatt tttggtatag gtgatacaag
   192121 agcaagagaa atttgtatta ctctaaaatt agatccagtc actaaagttg ctaacattac
   192181 tgaaaatcaa ctggaattaa ttcgtgtaga aattgctaag tatgaagttg aaggcgatct
   192241 tcgtcgtcaa cttgctatgg atatcaaacg tcttaaagat ttaggctgtt atcggggtgt
   192301 tcgtcataga aaatcattac cactacgtgg tcaaaggaca aaaacaaacg caagaactcg
   192361 taagggccct cgtcgtttaa ttaaataatt ataggtaaat attattatga tagctaaatc
   192421 atcttcaaaa aagaaatcta aaaaagtaat tactgatggt attgctcata ttcatgcaac
   192481 ttttaataat accattgtga tgattacaga tcgtcatggt aatacggttt gttgggcaac
   192541 ctcaggcggt tctggtttta gaggttcaag gaagtccaca ccatttgctg cacaagtggc
   192601 tgcaggtagt tgtggtgaga aagcattggc ttttggcatg aaaaacttag aagttcatgt
   192661 taagggtcca ggtcctggta gagattcagc aattcgcggt cttaacgcgc agggtttaaa
   192721 aattcaatca atcacagacg tgacaccaat ccctcataat ggttgtcgtc cttctaagaa
   192781 acgtagagta taaggataaa ttatggctag atatactgga cctacttgta aattagcacg
   192841 tcgagaaggc gctgacttat ttcttaaaag tggtattaga tcgttggatt ctaagtgtaa
   192901 ggttactcaa cttcctggta tgcacggtgc gagcgcccgt cgtcaaaaag gtacagagta
   192961 tggtttacaa ttacgtgaaa aacaaaaaat aagacgtatt tatggcattt tagaaaagca
   193021 atttcgttta tattataaaa aggcttcaca gaagaaaggt tctacaggtg aaaatttatt
   193081 atcactgctt gagtgtcgtt tggataatgt tgtttatcgt atggggtttg cctccacacg
   193141 tgccgaggca agacaactag tttcgcataa gtctattatg gttaatgggt tggttgttaa
   193201 tattccttct taccaagtga gtgttaatga taaaatttca attagagaga aggctaaaaa
   193261 gcaaagtcgt attcaattgg cacttgagtt atctggacaa tcaactcaac cacaatggct
   193321 tgatgttgat aacaaaacac ttaaaggtgt gtttaaaaat gttccttctc gtgatgaatt
   193381 accatcagac attcaagaac atttaattgt tgaactgtat tctaaataag gaatgaatta
   193441 tgcaaggtag tgcaagagat tttttaaagc caaagctagt tgagtcttct caaactggtg
   193501 ttaatgagtt caaagtcatt cttgaacctc ttgaacgggg ttttggtcat actttaggta
   193561 acgctataag aagaacgttg ttgtcttcta tgacgggttt tgctgtgact gaagttgtaa
   193621 ttgatggggt tatgcatgaa ttttctacaa ttgatggcgt tcaagaagat gtattagata
   193681 ttttacttaa tcttaaagag gtgtcagttg tattaaatac agttgaaacc gcacaagttg
   193741 ttattgacaa gaaaggtccg tgtgaaatta cagtagctga tattgagact aatggtattg
   193801 atattacgac attcaatcct gataaggtta ttgcaacaat taatgatgaa ggtcatatgc
   193861 gtatgacact taaaattact gctggtattg gttatgatgc tgctgcgtca cgtactgatg
   193921 aagcatcaag tattggtggt atgcagttgg atgcaagttt ttcacctatt aaacgcgtta
   193981 gttttacggt agatgcggca cgtgttaagc agaaagttaa tcttgataaa ttaaatatta
   194041 tgattgagac taatggttca gttaatgcgg aagttgctat taagcgtgta gcaacaatct
   194101 tacaagaaca attgtcttca tttgttgagt tagagctggt cgaggaagaa gtatcattac
   194161 caacatcaga agattttgat ccacagttat tagcagcagt agatgagtta gaattaaccg
   194221 tacgtagtgc gaactgctta aaggcagaac agatttatta tattggtgat ttaatccaaa
   194281 aatctgaaca agatttacta agaactccta atttaggtcg taaatcactt aatgaaatta
   194341 aagaagtatt aactgaaaaa gggctttctt taggtacaaa tattgaaaat tggccaccag
   194401 ttgatttaat gagtgaataa ggaacaaggt atgagacata gaaaatcagg tagacagtta
   194461 aatcgtaatg catctcaccg taaagcaatg tttaaaaata tggcaaattc attgttttta
   194521 tataagacta ttcgaacgac tttacctaaa gcaaaagaac ttagacgtgt tgttgaacca
   194581 ttaattacta aagctaaaat cgatagtgtt gctaatcgtc gtaatgcgtt ttcaaaatta
   194641 cgtgatagtg caatagttgc taagttattt actgaattag caccattcta taaagatcgt
   194701 cctggtggtt acattcgtat tttaaaagct ggttttcgca ctggcgataa agcagcaatg
   194761 gcaattgttc aattgattga ccttgaaact atgacagata caactgctgg aactactact
   194821 tcataaagga aaaatatatg ccctcaatta aagtaagaga aaacgaacct tttgatattg
   194881 cacttagacg ttttcgtcgt atctgtgaca gggctggtgt tattactgat gtaagaaaga
   194941 aggagttctt tgaaaagccg acttgggtta gtaaacgtat gaaagcagct gctgttaaaa
   195001 gaacacacaa agagatggct aaaaatcgtg tttatcgtaa gcgtatgtat tagaaatgta
   195061 attgctattt tagccagtga gtattgtaat cgcaattgta ggttgtgtga gctattaggt
   195121 actgacaatt actattacta gtgttttatt tgtatcattt gacgctgatg gtggtgaagg
   195181 tgattgataa tgttgtcaat aaagtcaaat aaataagttg ggtgattatt tcgatatatg
   195241 gcgctctatt tgtttatcaa tcaaggaagt acaaaatatg tattatgaag atgtaaaatt
   195301 acgtaaatta ggttaatata atagcgatta acttttaggg ttattaggaa aaaatctgtt
   195361 atttaaaatt cttatggcgt gaaatatcag aaaaattagg ttaatttatc cttaagttaa
   195421 atatggtatg agatgaaaat aagactttat gataacatac aaagataatt tcattgttca
   195481 ttatagtttt aatatttgca ttttagtatc ttattttttc gtgattctaa attgttttag
   195541 gagttaattt atctaaatcc attcgtgtac tatataagag ttaataaaat tttttctatt
   195601 aagaatgaaa atttatttag ttggtggtgc agtacgtgat cgcttgttgg gaattgcaga
   195661 tgacaatact gagaaagatt gggttgtagt tggttcatct agtactgaaa tgctggattt
   195721 aggttatcgt caagtcggta aagattttcc tgtattttta catccagata cacaagaaga
   195781 atatgcctta gcaaggatag aacgaaaatt aggtattgga tataaaaggt ttgaatttga
   195841 cgtttcaagc tcagttacgt tagagcaaga tttgtcacgt cgtgatttga caattaatgc
   195901 aattgcacaa aaagacgatg agttatttga cccattcaat ggtcaagaag atctaaataa
   195961 tcgtatttta cgccatgtat ctaatgattt tagcgaagat ccagtgcgtg tgttacgtgt
   196021 ggctcgattt gcagcatatt ttaaaaattt tggctttgaa gtagaacagg aaacttacca
   196081 attaatgaga caaatggttg cttcaggtga ggttgattct ctaactcctg agcgtgtatt
   196141 taaagaactc aataaagctt tatcatatgg aacaccatca gctttcttta aagtattaac
   196201 tgcttgtggt gcttatcaaa aagtttttcc tagtcttaat aatcacatat atcaaaatta
   196261 tagtaactct tttgagtttt tagataatct taatactaag gcgcatatta aattttctat
   196321 ttggcttaaa gatgagaata agtataatat taaatgtcct aaacagtatc aacaattatc
   196381 tgaacttact agccagtttt ataaattttc aaaggatttt attaataaat ccagtagaga
   196441 aatatttgat tttttcactc aaactgatgc tcttagacgc caagataggt ttgaagattt
   196501 acttactgta tttaaattat tggagattga tatcctacct attaaacatt taaaaaattt
   196561 acttaaaaat attgatatat ctagattgga taaattagat tttggtaaag ctattcaaat
   196621 agagaaaaaa ttaattattg attcatttat tagaaaaata aagaaataat attacaaaaa
   196681 tgtatattgt aatttagtac aaatatattt ctttataaag ttatttgatt aaagtttata
   196741 agtaagttgt tttcttatta aacataattt aatttttatt ctgggtttaa cttatgatta
   196801 aagtttgaat cagaggttaa atgattattt cttgacacga caaaacaagt aaaacttaca
   196861 ataatcacag gcatttttat taggtaagac ggcggcgatg ccattttgaa aatcaaaact
   196921 agcagtgttt aggatgtttt gccagatttt aagttgtttg ttccagcttt gacattttcc
   196981 tttatatttg gattgtttag gtagtgagtc tgagtcttct gacaatcctt tgaaatttat
   197041 tttgtgtgag gttagttcaa taaaagccgc accttgaaca ttgttagtaa tagcgtaaat
   197101 agggagttgc ggtttactaa tagcagtatc acaccaatta taaattgaag ttgaacttgt
   197161 tttgtaatcg aagattattt tgtcaccatt actcatttga tcaagtctat ctagccgaat
   197221 tttgaattct aaattggcaa tattaattgt aatactttgt tcagttttta gtatataaaa
   197281 atcttctctg agtttatcaa ctgcaatgaa actatgaata agacgagaaa gtctgagttt
   197341 ttctattttt ttaaaactag agcttggata gtgtcttagt gcggctttta ttgtattaag
   197401 aataagtttg tcaagctctt tattgttaag tgctaaaagc tgtttttttg aagtaatttt
   197461 ttgataaata tattgtaaag tgttgtggat aatatatcct tgttctaatc gatttatacc
   197521 gatatgtggt gcatcaaaat ttgggatatt caatcgatgt atgaagcctt tgaaagcaca
   197581 agccatttgg tcttttaaaa tacaaacacc tgatttgact tgggtttttt ctaaatgagt
   197641 agttttggta tcattaatag attctagcgc aatggggaat attttttgaa tatggtttgt
   197701 attaattgat gtgtcaaatt ttaccagtgg tgaaggtaat tgtttactac caaggtgtgt
   197761 tgctgcatag gaaaaaatga ccttaccggc aattgaattt aagctttcca gtgtgttttt
   197821 agcatcagtt gcaattagtt tgtaatctgt gtgtgggata tggtgttttg tgctaatatc
   197881 atacgtaata aagcgtggta aattgagttg tgtagataca aactgattag tcatacctaa
   197941 tacccaagct tcgtcaaaat ataatccatg agcttctgaa acacttagaa tttgaatgtt
   198001 ggttttgctt gcttgtgctt ggaaaattat ttgtgtggtt aaattattta attgtttaat
   198061 agcagattga gtgctaactt tatcgtaata agatgagagt cgatttagct ctaaactagt
   198121 ttctaagtat tttttaaata tttgatattc ggtattgctg agatttctat cagtagcaaa
   198181 tccccaagtt ttaagcgtgt tgttaaaagc taaaaggtgt gattctaatg tgttattggt
   198241 tagttgttca catttgatgt tatcaataat agtttttaat attgggcatt tggatagagc
   198301 ttcattaatt ttatctaaat taaattgatc agtcaataaa gacaaaactt ggttttttaa
   198361 caaatttcta tctgatcttt ctttttggta gccaaataca taaacacaag taacaacttg
   198421 gttaaataac gtgcttctaa ttttgttgtg ttgtatttga gcggagagtg ttaatattga
   198481 taataaatct tgaattatcg ggtattgatt taaacgtaac cctaatgata tagtgtagga
   198541 tttttcctca atttcagtga gtaaatcacc aaaaacttga tcaaaaatag aacttaactg
   198601 atactttata tcattagaac ttggatttac aatagcaatt gatttattag ggttgatatc
   198661 aaagtgtgtt tttgcccact tagctgcttt gaagatttcg cttgtgacgg tgtcaaaagt
   198721 aagagctgat acattgtaag ttttgatagc gctaatttgt tggtatccaa ttatatcaaa
   198781 taagagttgt tgttgaggag ttaaagtttt aaagccgtat atatgaggtt tagttattga
   198841 tgttttggct ttaataatta accttggtag gtcttgtaaa tcaatcaaat ctaagtttaa
   198901 tttagtgttc tgataggtat taatccaaat gctaaataat tcagatgagt gtatttttga
   198961 acgatataac tcagataaat caattaaata attggtgcaa taattataat ttttaatcac
   199021 ttcatctagc agacgatggt tggttttttg ccctaatttt tgtatagatt gtttgataag
   199081 atatcttgat tcaatctggt caataaagcg taagtttgag ttaggattaa tttggcgcca
   199141 agtgtgaagt aagtactgct tccaagataa ggttattggt aattggctgt taccatgttg
   199201 aatggtgaat gtttttttaa aagcgagtac ttgttgatta ttggctaaaa taataatatt
   199261 tttagcatta agtttggtta aatcgacatt aatcaacata accaaaaaaa gtatctaatc
   199321 gagtccacaa tttttttaag ccttgttttt ttaggctaga aaataactgt acatcaacat
   199381 aagagtattt tttgatttga tcaagaactt taaaatacgt attgctggca gcgatttttt
   199441 tgagtttgtc agatttggtg agtatgattt gtgtgggtaa atgaatatta ttacaccagt
   199501 caagcatcat ttggtcaaat ggtttaagtg gatggcgaac atccataact agtactgcac
   199561 cgcgaagaca atcgcgctga ttgaagtact cattcatgtc tttataccat tttactttga
   199621 tatgttctgg tactttggca tagccatagc caggtaaatc agctaagcga cgatctttgt
   199681 caagttcaaa aaaaaccaag tgttgagttc tgccaggagt acgtgatact ttagcaagtt
   199741 tattttgtag tgttagtgta ttaatggcac gtgacttacc tgcatttgat cgaccagcaa
   199801 aaataacctc atatccttgg tctggtggac agccttttaa agaagggcag gagagtagaa
   199861 atttagcttg gtgatagtgt ttgcacattg ttaaaatata atgtataata gaattctggt
   199921 gaattattta ctactaattt tactataaat agggagaaag taatgaaaag aattttatta
   199981 gtggcagcta tcgctacatt tacaataggg tttgctcaag cagacggtgc agaagattat
   200041 gctagcagtg gttgtggtag ttgtcatggt tcgacaggta tatcagttgt tccaatatat
   200101 cctaatcttg ctggacaaaa cgcggcttat actgttaagc aattaaaagc ttttcaatca
   200161 ggtacacgca aggatatgac tatgaacgca atggcgtcaa taattattgg taaagaacaa
   200221 tcaattgctg attttttagc aatacaaaaa taacccttta tgaataggta attgctgatt
   200281 aggtcatcta attataaaat tttaatagaa caaggttaat gtataattct ggcttatttt
   200341 ttttcaaaaa catatattct tatgaataaa ttagcctcaa tttttattat tgtaattgcc
   200401 tttacttcag tcaatgtttt tgcgtctggt gatgttaaca aaggagaagt tattgcgtta
   200461 acttgtgttg cttgtcatgg tgttcatggt aattcagtag tagctgcatt tcctaaatta
   200521 gctggacagg gtgaaggcta tttattaaaa cagttacaag attttaaatc aaatactcgt
   200581 caagatgcaa ttatgaaagg cattgttgca tcgttaactg agaatgatat ggagaattta
   200641 gctgcttatt tctctaagca aactgttaca caaggtgtta ctgttaaaag ttctaatatt
   200701 gacttaggta agaaacttta tagaggtgga aataagagca aaaatataac agcttgtatt
   200761 gcttgtcatg gacctacagg tgctggtatt ccttctgcta gatttccagc cttgacctat
   200821 cagaatgcga cttatatagc taaacaactt atcaattttc gtcaagatgc atataatact
   200881 caaatggata ctagtgcacc tgaacgtagt aatgattatg aaggtatgat gagaaacatt
   200941 actaaatatt taagtaatgt agaaattgag gcggtttctc agtatattgg taggttgcat
   201001 taaagatgag ctaagactta gaacaaacat tcttgattaa taaataaagg gtagttatac
   201061 tgcccttttt cattgtctgt gttttaggta taattgtttt tttcaagtat aagaaacgga
   201121 tttaaacgca atgaaaactt cattagaaac attaaagggc ctatctagat cattaacaat
   201181 agatcttcct attgatattt ttaatcaaaa gatggataaa attctacaaa aaatggcatt
   201241 ggaagtgaat attgatggtt ttagaaaagg caaggttcct atttctatcg tacgtaagcg
   201301 ttttggtaat aatgctaatt cagacgtaat taatgagatt gtaaatgaga ctttgactga
   201361 tgcattagca caagtcaagc taacacctgt tgcacagcca gttatcacta aagttgactc
   201421 gaacagcaat aagaattttt cttatacagt agaatttgaa gtatttccta agattaaaat
   201481 agctgatttt tcagagcttt caattgagca aactaaggtc aatattacca aagctgatga
   201541 gcaaaaaaca ctagatggat taaaagatcg attgactgaa tataaagctg ttcaatgtaa
   201601 atctaaaatg ggagatagat tatcgattga ttttaaaggc ttaattaatg gtgaaacatt
   201661 tgatggtggt gaggctaaag attttaaaat agtgttaggt aaaggttcaa tgattaaagg
   201721 ttttgaagag ggtttaatag atgtagctta tagtagtaga gttgtgttgg atttaacatt
   201781 ccctaaagat tattatatgg ataaattagc aagcaaggac gttacttttg aaataaatat
   201841 taatgaaata gcctcaccta aagaactaaa attagatgaa acatttgcta agaagtttgg
   201901 tgaaaaaaat atgaacgctt tgcgtgttag tatgaaagag caaatgaggg ttgaagttga
   201961 tggacgtatt ggtcatctaa ataaaaacgc tatttttgat aaacttacca cagcaaatcc
   202021 gtttaatgta ccacaacata gtattgataa tgaagcacaa aatttgttca aagcaatgca
   202081 agatcgtatg caacatcaag gtttatcaac acaaggtgaa atgcctatta ctgcctttaa
   202141 tgatgaagca caacgccgtg ttaagttagg tttattagtt aatcaaattt ctagagacta
   202201 caagttaagt gtcagtatga aacaaattga tgaaaagtta aaagagatat ctaagacgta
   202261 tggtgaaaat gctcaacaaa tgattgattt ttataaccaa gatccaacaa gaaaatcaag
   202321 tattgagtta ttagtagttg aaaaaatggt acaagattta attttagata aggctcaagt
   202381 aacttttaag cagaaaaaat tccaagaaat tacacagtag ctaaatgaat attaaaaatt
   202441 taaatcagat cccaatagtg gtagagcagt ctgctagagg tgaaagagct tatgatattt
   202501 attcgcgtct tttaaaagaa cgtattattt ttttagtggg tccaattgaa gattacatgg
   202561 cgaatgtagt tgttgcgcaa ttactttttt tagagtctga aaatcctgat aaagatattc
   202621 atttatatat taattctcct ggaggatcag tttctgctgg tttagcgatt tatgatacca
   202681 tgcaatttat caagtctgac atatctacct tatgtattgg tcaggcagca agtatgggtg
   202741 ctttgttact aacagctggt actaaaggaa agcgtttcgc gttgcctaat gttaggtgta
   202801 tgattcacca acctttagga ggattttctg gtcaagctag tgatgttgac attcatgcac
   202861 aagaaatttt aaaagtaaga gcaaatctca atcaaatttt caaacttcat acaggccaag
   202921 tgattaaaac tattcaaaag gatactgata gggataattt tatgtcagct gatgaagcta
   202981 ctaaatacgg cttaattgat aaagtattgg caaagcgcta aatttatgaa agatgataat
   203041 caagaattag tttgttcatt ttgtggtaag attaaatcta aggttgaacg tttaattgct
   203101 ggtcctggtg tttatatttg taatgaatgt attagatcgt gccatgattt aattgaaaaa
   203161 caagcattac aagaagtaat tgatgaattt aaaaattggg attacacgcc taaacagtta
   203221 accagttttc taaatgatta tgtaattggc caagaacatg ctaagaaagt gctatctgtt
   203281 gcagtttata atcattacaa acgcctccaa aatgatcata tatctaatga agtagaattg
   203341 gataaatcta atattttaat gattggccct acaggctcag ggaaaacatt attggcacaa
   203401 acattggcac gtattttaga tattcctttc acagtggctg atgctaccac attaaccgaa
   203461 gcgggttatg taggtgatga cgttgaaaat gtagttaaga atctattatc aaaatgtgat
   203521 tttgatccag atcgcgctca acgtggtatt atttttattg atgaaattga taagatttct
   203581 cgtcgttccg actcaccttc tattactcgt gatgtttcag gtgaaggggt acaacaagct
   203641 atgcttaaat tgattgaagg tactattgca agcgtacctc ctcaaggggg gcgcaagcat
   203701 cctaatcaag aaactattga tgtagacact tcaaatattt tatttatttg tggtggtgct
   203761 tttgatggtc tagataaaat tattaacaga cgtgttaaaa aagttacagg tataggtttt
   203821 tctgtagatg tgaaagacca aaatgaagag aaagcattga gtgatttatt tgtattgatt
   203881 caaccagaag atttaattaa gtttggttta attccagagc ttgttggacg tttaccagta
   203941 caaacagtac taagtgagtt agatgaaatt gctttagtga aaattttaat agagccgaaa
   204001 aattcagtga ttaaacagtt tcaagaaata ttttccatgg aaggtgttaa actgattttt
   204061 aaaaaaccat ctttacttgc tattgcaaaa ttggcaatta aacgtaaaac aggcgctaga
   204121 gggttacgtt ctatcttaga agatttgtta ttagatacaa tgtttgaatt accatcactt
   204181 cttgatgtga ctgaagtggt gattgacaag acagtggtag aaaagaaaaa aaaaccactg
   204241 attgtctatc aatctcaaaa acgtgtcaac aactctaaaa aggttggtta gattgaggat
   204301 tataaaatat tctttgcaaa gaagaaagaa tatcttagtg tatgttaagt taccaactag
   204361 tcctagtgaa acttagttgt aaactaataa acgataatta gtatataaat ggttactatt
   204421 attaatagga agtttgacat tatttgatta tgtagagatt aagaagaaac ttcatatgtt
   204481 aatattttat tacatagaga ttggtgcaag taatatcatt atttattgag tttgtctttc
   204541 atttcagata gaagaaatgt taattttctt catcaagctt tggctaagca tcttaatggt
   204601 atgataactt gtgcaaatag atatatcgat tatgaaaaag taaattattc tgtgatttgg
   204661 gtacttgaaa tctttgttac taagcactat ctatctaaat tactaaactt caaaggcgtt
   204721 agattgttat ggcaacagaa ctcaacaatg aacaaattga tttaagtaag agtaatattc
   204781 cattattacc cttgagagat gtggtggttt ttccacatac tgttatgcca ttatttgttg
   204841 gtagaaagac ctctgttaat gcaattactc gggcaatggc tacgaataaa tatatttttt
   204901 tagttactca gaaagatgat caagtggaaa gccctacggg tgatgactta catcaagttg
   204961 gaacattagc aactatcttg caaatgttaa aattgcctga tggtactatt aaggtcttgg
   205021 ttgaaggagt tagacgcgct aaaattaaac aaattgtaga aactgatggt ttttttgaag
   205081 tgagtttaag tgaatttagt ttacagtcta atgatgatac tgaaataaaa gccatgatgc
   205141 gtttagcatt agatagtttt gagaattata tcaagttaaa taaaagagtg ccagaagagg
   205201 ttcttaagat gttacaagaa gttagtaatg ttgaacgttt tagtgatgtg attattgcta
   205261 atttaaatct taaagtatct gaaaaacaag ctttattaag tgatgataag gctcaagata
   205321 ggcttgataa gattttatcg gtgattcaag gtgaaattga cgtgctagga accgagaaga
   205381 aaattcaatc acgtgtacgc aagcagatgg agtctaacca acgtgattat tatttaaatg
   205441 aacaaatgaa atccattcaa aaagagctag gtcaggctga agatgaaaat gaaattgaag
   205501 agttacaagt tggtattaat aaggccaaga tgtcaaagga agctaaggaa aaagcacaaa
   205561 atgagttaaa gaaactttca cgtatgtcat cacattcgtc tgatgcatct attattcgta
   205621 cttatattga gaatttgtgt gatgtgccat ggaagaagaa aactgttatc aataaagacc
   205681 ttaataaagc gcaaaaaatt cttgatgatg atcattatag tttgaataaa gttaaagaac
   205741 gtatattaga acacctagca gtacaaacac gtgttactca taataaggct aatattttat
   205801 gtttggttgg tcctccagga gtgggaaaaa catctttagg tgaatcaatt gctagagcag
   205861 ttaatcgtaa atacgttcgc atggcgcttg gtggtgttag agatgaagca gaaattcggg
   205921 gccataggcg tacctatatt ggcgccatgc caggttcaat tatacagaaa atgcagaaag
   205981 tgaaagttaa aaatccactt ttcttattag atgaaattga aaaaatggca agtgattatc
   206041 gcggtgaccc ttcttcggcg atgttagaag tattagatcc agaacaaaac cataccttta
   206101 atgatcatta tttagaagtt gactatgatt tatcacaagt aatgtttgtt gcaactgcta
   206161 actcacttga tttaccacaa ccgctattag atagaatgga aattattgaa ttatctggtt
   206221 atactgaaga tgaaaaagtt gagatcgcta aacgccactt aattaaaaaa gcaatgaatg
   206281 gtaatggtgt taaggataat gaaattaaat ttcaagatga tgctatttta gatataattc
   206341 gttattacac acgtgaagca ggtgtacgtg gtcttagtag aacaattagt actatttgtc
   206401 gaaaagtagt taaagaagta atcttaaaga agtgtgaaac taaggcttat attaatgcta
   206461 agagtttaga aaaatattta ggcgtgagaa agtttcggtt tggactagct gagcaaaata
   206521 atcaaatagg agaagtaaca ggacttgctt ggacttcagt gggtggagat ctgttaacta
   206581 ttgaagctac tgcctataaa ggcaaaggta aacttaatta tacaggtcaa ttaggtgatg
   206641 taatgcaaga gtcaattcag gcagcaaaat ctgtggttag gagtatggtt aaaaaatttg
   206701 gtattgatga gaattttgac gaaaaattgg atattcatat tcatgttcct gatggtgcaa
   206761 cgccaaaaga tggtcctagt gcaggagcgg ctatgactac agcattagta tcagtactca
   206821 caagtagaaa ggttaaagcc gatgttgcta tgacagggga gattactctt agaggtgaag
   206881 ttaccccaat tggagggtta aaggaaaaaa tgttagctgc attacgtggt ggtattaaaa
   206941 cggttattat tcctgatgat aatgaacgag agttgtctga agtgcctgag aaaattaaag
   207001 gaaaacttaa ggttattcaa gtgaagtgga ttgatgaagt gttagatatt gctctagaaa
   207061 aataaaatta tttatggcct aatgtaagaa taaccttgtt gttgtaaatt tccaatacga
   207121 actacaccag aagttacaat attaattcct tctactagtg ttggaaattt accttttttg
   207181 cgtttaatag ctttcatagt gttgtgacaa gcactaaagg taatgttatt cattatcatg
   207241 gattcaatac gatcagaatt tttattgctt tgagttaata tacttaaacc aggaccataa
   207301 gctacaattt caatatcaac attatcaata ccgtagtatt tttgtaggtt tacagcatta
   207361 tttagaacaa ttttttgtgt tctaatatca tctgtgctga tttgaatcac atacttttga
   207421 tttactgctt gagcgtttag tgttaatagt ataagtattg taatactgaa taatattctt
   207481 ttcatttttt ctcgctataa ttgaaaaata tctctatttt gtataaagac atcaattatc
   207541 ttacgctatt ttgatgattt tagagtaata atagccatca gttattactg actatcaata
   207601 ttttagttta gttttatttg ttatttattt gatattagtt attcaaaaat attgttaata
   207661 tgataatatt tttaagttta tgtagaagta tttgtttaag atgctatgta ttttgattga
   207721 ttattgtgaa ttgttctaaa tacaatgatt tagtattata ttgattgtcg tattgtaaat
   207781 tattgaaatt aagttagaat tttttcaact aagttgagat atggcgtatg tcataagttt
   207841 atttaagcag attttgctag gttaaataat gattatcttc taatattaaa agaaaattaa
   207901 tattaattta aatataacga ttaattagat aatgtaattt tattaatctt atctttttag
   207961 gtaaaatacc tactattgta ttttttaata aggtattgaa atgaagttta cactgattaa
   208021 tgaaataatt caacacttta agggcgatgc tgtggtcgta ttttctaatt ctaatacggt
   208081 ttttaatgat gataatattc aacaattaat taaacttaat cattttgact ctaaacctgg
   208141 gaaggtgttg ttattaaatt tggtttctgg ttttaaatcc aaacaagtga ttgtttctgg
   208201 acttggtgat gcgcctataa gcgctaaaaa ctatgttaaa gcgttgaatg ctgtgattgt
   208261 tatacttgtt gaaattaaag ctaaaaactt aatggttcaa catgttggaa ttaaaggttt
   208321 taatgaactt tgggtgcatg aaataactgc taaggtaatg tgtaacgcaa cttacaaagt
   208381 tcaaaaagtg ggtaattata aaaaacaaaa tagtggtatt gaacgtatta ctattcaatc
   208441 aactatggat agtgtatatg gtttaatgaa aggtcaagca attgctgatg gtatgtcttt
   208501 aacgcgccat ttaggggact taccatctaa tgtatgtaca cctagctatt tggcaggtac
   208561 tgctatatct ttggctcaag aatttaatct tgagtgtgaa gtcctggaag aagtggacat
   208621 ggagaaactt ggtatgggtt cgttattggc agtttctaaa ggctcgagcg agccacccaa
   208681 actaattagt ttgagttatc gaggtaatgg taatgaaaaa ccgattgtac ttgtaggcaa
   208741 aggtgttaca tttgatagtg gtggtatttc actgaagcct ggtacgggta tggatgagat
   208801 gaaatatgat atgtgtggcg cagcttctgt attaggtgta atgcgtgtta ttgcacaaat
   208861 taagccaaat attaatttag ttgttgtttt accagcagtt gagaatatgc cagcacataa
   208921 tgcctctaaa cctggagatg ttgttaaatc tatgtcaggg aaaacgattg aaattttaaa
   208981 tacagatgca gaagggcgtt tgattttgtg tgatgcgctt acttatgtta agaaatttaa
   209041 tccagaagtg gttattgata ttgctacact tacaggtgca gtagttgttg cactaggtaa
   209101 gtataattca ggacttatga gtaatgataa aaatttggct aatgatatca ttagtgcttc
   209161 taaggtttca cttgatggtg tatggcaatt acctattgaa gacgagtatg atgaattgtt
   209221 gcaatcaaac tttgccgata tggcaaatat tggaggtagt agtgaagctg gttctattac
   209281 tgctggttgt tttttgtcca gatttaccca aggttatcgt tgggcacatt tagatattgc
   209341 aggtacagct tgggtaagtg gtgataaaaa aggcgctaca ggtcgtccag tatctttatt
   209401 aacacaattc attatggatc aagttcaaaa gagattgtga tgttagatat ttgaaaatat
   209461 aactgttgct gaagtgacta atgatttatt ttgatggaaa tagtcaagtt gtctggtttg
   209521 ttgatgctag taaaaagata ctaagtatga tgatgtaaga tgattatgag tagtgaaaac
   209581 ctaaataagt gggattaatg tgtttttgct aaataaatat gaatacattc attcaaggat
   209641 attaaattaa ttaatccatt gatatgttaa atgagaatgt tgtatgaata ttggttaaaa
   209701 ttaatacgat taaagtgtgt taaaacagta tattttggtt taatttttta ttaactttac
   209761 tttatggttt tttaacttat gtgttaaatt ataagttagt agtataaatg gaaggattag
   209821 tttttctttt ggttataatt aaattctaga tagctgatat caagtatatc gatagaaaaa
   209881 tactccgtga ttttctattt taaatacata cgtgggtggc atatatgttc ctgagtattt
   209941 ataaaattta ataggtaata cgttattttt aatacgtgta agatttaaat tttctaaaat
   210001 ttgtttaaag aataatttac cataaacttg aataactcct gcacatagtt ttgatgggtc
   210061 gattaaatat ttatacacat acttgtgtgt gtatagttgc tttgggtaaa tgtttaataa
   210121 attcgcttga actatacttg cttggatagt aaaggtttgg aactgaaaga taatagcctg
   210181 ctatattaat acaagtcttc aatgaaataa ttagccgtaa aatttttgcg tatatgttgt
   210241 ttattaatac aagtgatatt aaagtctagt tcatagtaaa tagattttat ttttttattt
   210301 aagtaggtta ttaattttta atattcaaaa aaccgtcttt taggcggttt tttgaatatg
   210361 atattgtttt ctaaaaatca ccttttgcgc cattattctg aattacagtc attgctcttt
   210421 ggataactaa agccttttta agtaagtaat caggtaatgg tgcaccacca tagatcatag
   210481 cattcatgtt taacatatat agccatcttt gtccagattt atcttcaata agtgccagtc
   210541 tacaaggtaa gtatgctgaa aatgcatctg agtgatcaac cattgtcatt gctgttcgtg
   210601 gtgaacaata ttgataaatt tttaagaatc tttgcttgtc gttagtttgt aattcaacca
   210661 tttctgataa gggcaacatg cctacagaac gaataccttt agcagttgca atactttcca
   210721 ttgcttcttc aacatcttca tttgaaacat cgtcagctac ttttacacgc acaatagaag
   210781 ccatagcaat atcacctgta tcaagtagcg tgttgatcat tggcatgtac accttagaca
   210841 tagactttgg atgtagtttt ggtgaaatta tttcactgat tacttttcca gttataccat
   210901 cgtatttgat ttgtagtgat acagtataat aaattgtaat agcgccaata ataattaata
   210961 accatttgat tagattgata attccactca tttatttttc ctactataca atatataaaa
   211021 tatttctgca ttctagcagg ttaaaaaaaa atagttaatc tatcactata tcctaatttt
   211081 ctaatatttt ttttgttata caatccttaa actattaaag acaatgctag ttaagctaac
   211141 catgccaaca atcttaccat tatctaaaac tgggcaacga gaaagattaa aatttgttaa
   211201 tagttttgca caataacgaa tatccatatt agagtggact gaaatggctg gtttgttcat
   211261 aatttcatac acattaactc gatcaagtgc tcggtctttg gcaataactt tggaggcaat
   211321 gtcagaaatt agtactacac cgtattcatc atatacatga gatttgtcaa ctaaaagcat
   211381 ttttgttttc ttatgttgca tgtcattaag tgcattttgc acggtgcatt ttgaattaac
   211441 aatatcaacc tgtgtccaca tgacatcttt tactatggtt gttgttgtat tattagtcat
   211501 tatatttttt cctttatagt gtgttctagt gcatgaattt gatgcataac gccaacagca
   211561 tcctctacat caacttgaaa agcaattcct tcttttggat tggattcaaa attgcctgta
   211621 tcagcaattg tttccaatat atctctagaa agatgtcgct ctactaacaa taataagaca
   211681 tctctaggag tttcaatatt aagtcctaaa aatgttttgt tgtgtttgag gccttctcct
   211741 cgagcttgag aaataatggt tgatcctgta gcgccttttg tcctagcggc ctcaagtatg
   211801 ttgtcagttt tattagaatc aacaaaagca ataattagtt taaagtgcac agcacctcct
   211861 attttttatt ttggtttaaa aattttataa tttgtacata agtcatcaca ctcataatag
   211921 gaaataatga agcaaaagcg attaaaccaa aaccatcaat aagtgtagag cgtccatcga
   211981 ttgtactcgc aagtccaagt ccaagagctg caaccagtgg tacagttacg gtagatgttg
   212041 ttacaccgcc agaatcataa gcaagtgcaa taatattttt tggtgcaaag taggtttgta
   212101 taagtacgat aacatagccg gaaataataa agtaatataa tggtaatcca gttacaatgc
   212161 gaaagcttcc gatggtaata ccgacagcca caccaatagc aactacaatt cttagaggcc
   212221 ataccttgat aaaaccacca gatacttgat tggctttaat ggcaattgct agtaaagctg
   212281 gttcagcaat ggttgtggca aagccaatac tggctgcaaa aatataaatc cagtaataat
   212341 ctttccagct aagtgtgtca ttaccgataa aattacttga tgttagttgc tttgccatta
   212401 gttttcctag aggaaatagt gctgtttcta acccaacaat aaataaagtg agtcctatcc
   212461 aaactaaaat aaatccagta ataatcttct ttaaatatgg tattttttgt ttaagaataa
   212521 ttatctgaaa accaagtaat atcactgcaa taggcataat atcccagaac atattgataa
   212581 aattacccat taaattcatt gtaatatacc aaataacatt actgcaatga taggtagaag
   212641 tgaggcaatg gcaatcattc caaaaccatc tgttaaagga tttctgccac taattgaact
   212701 ggcaagacct acaccaagtg cagtgagtaa tggtacagta atggtacttg tagtaacacc
   212761 acctgaatca taagcaaagc cgatgataaa gtctggcgca aagaaagtag tagcaattac
   212821 tagaagatag ccgctaataa ttaagtattg tattggccaa ccttttaaaa ttctgagtac
   212881 accaattact acagctaaac ctacagaaat agctacagta agacgtaagg tttttgcata
   212941 attattaatt tctgtttgtg tattgacaat accaccaagt ttggcaactt tagctgcctc
   213001 attagtaatt gctatgaggg caggttctgc cactgtggta ccaaatccta aggcaaatga
   213061 aaataataat agccaaaaga ttgaaccttt tttaacaaaa ccataggcta atgtttcacc
   213121 aataggaaat aatcctagtt tgagtccgta tacaaataaa gtcaaaccta atagaacaaa
   213181 tcctgtccca atgataatat ccatcaagtt tggtatgctt tgttgaagca caataatttg
   213241 gaaaaaagta atgacaccta ttataggagc taaatcttta gcactatcag ttagattttt
   213301 agtaaactgt tgaacagttt ttttcataaa gattttaagg tgtgtgttat tttttttgat
   213361 taaaatgttg ggttaataat aaaaatttat cttcaggtaa caatattatt tattgaatta
   213421 taatacaatt ttatggttac cattttatta attaacggga aaaaacaaac caaacttagt
   213481 atgtttaatc gtttagtgca atttggcgat ggtttatttg aaacttgttt aattgaagat
   213541 tctaggttgt tattttggtc taagcacttt ttaaggctag aaaaaggttg tgagaagtta
   213601 ggaattcata aagtgaatga gggtatttgg cttaaagaag ttgctcaagc atttgctctt
   213661 tctagattaa atcaagcagt ggttaagatt attctttctc gcggtgaaag tacaagaggt
   213721 tatggttatg agaaaaacat taagccaacc cgtattataa ttatttaccc tatgactgac
   213781 ttaccttggc aatatgagtt gggtgtgtgt tctagcggtt atgttggtaa tcaattgtta
   213841 tctgaaatta aacattgtaa tcgtttagaa caaattcttg caaggtcaga attacaagga
   213901 caagagtgta ttatgttaga tgaaaattct ttggttattt cagttactca aggcaatatt
   213961 tttgccatta gcaatcaagt aattcttact cctagtctga ctaattgtgg tattgagggt
   214021 actctgaggt ctgtagtttt tgatttagca aaagaattag acttgcaact taagatttgt
   214081 tctttatcat tagttgagtt gcttgaaaca gatgaagtat ttattaccaa tagtgtaatt
   214141 ggtattaaac ctgtgtctaa aattaatcag aagttattta atcatcatca aattacggat
   214201 cgattaatta gtgcttttgt atgctctaag aataaccatt cattgtcaat tttgcttaaa
   214261 tcaaaatcgt tttatttgag gtttatcttt atatttgttg ctattttttt actattctga
   214321 atgtatttgt aaaatggtat caaaacaaat aatttagata tatagcaaaa tatcttaaga
   214381 cgttagtttt catttgattg caaataattt agggtgtcta agttatatca attctagtat
   214441 tttatgtgat tacttgctaa attattcaaa tgagaattta aaatttaata gcctttataa
   214501 ttcttataga aataaaggat tactactagg ggttaatctt ttcggtgggt gtaaattagt
   214561 tatatgcttt attttttttt tgctaaaaaa gatgattctg atattttata aatatttatt
   214621 gatataattt ttatattatt aacaagtatt tataatctat ataaaatatc cggcatgcaa
   214681 agaggaaaat ttatcactat tgatggtgtt gaaggtgctg gaaagagtac acaaattgat
   214741 tttatttgta gctatttagc taaaaaaaac atcaatgttg ttctaacacg tgaaccaggt
   214801 ggtactaaac tgggcgagaa aataagagca ttattattaa gtattgatac ccagttaatg
   214861 gataatgata ctgagttgtt attaatattt gctgctagaa atgagcatat taagactaaa
   214921 attattcccg cccttaatag gggagattgg gtattaagcg atcgttttac ggatgcttcg
   214981 tatgcttatc aaggtggtgg tagaggtttg agtattgagc gtattgcact tttggaacaa
   215041 tgggtattac aagatttttc tcctgatgta actttattgc tagatgtacc agttgcatta
   215101 ggtatgttgc ggattaaatc tagaagtcgt aaggatagaa ttgaacttga aacaaatgat
   215161 ttttttaatc gtgtgagaga tagctatatt aaaaggtcta agcaatttcc tgaacgtatt
   215221 aagcttattg atgcctcgca aacacttaag gaaacaactc agcaaattaa agttatttta
   215281 caagcgttat gaaccttcct tggcataaaa atgcatggtc taaattacaa aatatgattg
   215341 atcaagattg tttccctcat gcattattaa taacaggtgt tgaaaagatt ggtaaatttg
   215401 aacttatgca acaattagtt ggtgttttgt taaaggatga tattatcatt agaaaagata
   215461 atgttagaaa taatttagat tatcctgtat taattaggcg ctcaaattat cctaatatgg
   215521 tttattgtcg tgcaggagaa atggttgaaa aaaacaagaa tcgatctaat aatattcgta
   215581 ttgatcaagt acgtgttttt tgtgatgctt tgaataaaac tgccgatgaa ttacaaattg
   215641 gggttatttt ttatggagat caaatgaata taggtgctgc caatggtttg ttaaaaactc
   215701 ttgaggagcc tagaaaaaat acgctaatta ttattttagc gcatcatgtt gaaaacttgc
   215761 caattactat tgtatcaagg tgtcagaata tacatattac tccgacgtat gatcaacaaa
   215821 cttgtcagtg gctaattgaa catattggca aaactcaaaa gaaagattat aatattaaac
   215881 agctattaga gagtacacat ggtgttccgt ttaaagtatt gtctgatttg tctgatggta
   215941 attttactca ttatcagaat taccaaaacc agttgcttaa tattgttgct aatccattga
   216001 tgatagtaca aattaaagat tttgagggta atgaattggt tattttaaat tgtttgcaaa
   216061 atattattat tgaaggaatt agattaaaaa ctgtacatca agaagatgct attactgaac
   216121 tttatcaagt tattgtaaca gtaaaatttg aatttttatt caaattgctt gatgatattt
   216181 atcatgctat taaactatta aaaaccactg ttaatattag cttattaatg gataatattt
   216241 taattgtctg gtcacatatt gttcatttaa aaaaatatcc acaaattacc aataaacatg
   216301 taaagattat tttttaataa atagggggaa tatgaatcaa tcagaagttt tatttgcaca
   216361 agcaagaact gttatttctg gcggagtgaa ttcaccagtt agggcattta atggtgtagg
   216421 cggtaatcct atttttttta ctcgtggcaa aggtgcttat ctttttgatg tggatggtaa
   216481 taagtatatt gattatgttg cttcttgggg tccaatgatt ttaggtcatg ctaatcaaga
   216541 ggttataaat gctattaaaa ctaatttgga gaatggtctt agttttggtg cccctactca
   216601 tattgaaaca atgctggcag aaaaggtatg tgaactaatt ccttcaattg aattggttcg
   216661 tatggtaagt tcaggtacgg aagcaactat gagtgctatt cgtttggcac gtggttatac
   216721 tggtagagat aaaattatta aatttgaagg ttgctatcat ggacattctg atgcattatt
   216781 agttaaagca ggttctgctg ctttaacatt gggtgtacct acttcacctg gtgtacctaa
   216841 agattttgca aagcatacac tgactttgga atacaacaat attaatcaag tatatgaaat
   216901 actcaaagaa gtgggtactg aagtagcttg tattattgtt gaacctgtgg caggtaatat
   216961 gaattgtatt ctacctattg atggtttttt gcaaggttta cgcaagttgt gtgacgaata
   217021 tgggattatt ttaatttttg atgaagttat gacaggtttt cgtgttgcac ttggcggtgc
   217081 acaagaattt tataacgtag aacctgattt aacaacattg ggtaagatta ttggtggtgg
   217141 tttaccagtg ggtatattcg gtggtaagtg tgaaattatg aaatgtattg caccactagg
   217201 acctatttat caagcaggaa cgctttcagg taacccaata tcaatgtcag caggattggc
   217261 aatgttaaat gtattgtcaa aagacaaaaa tttttatact actttaaata ttaaagtcca
   217321 aaaattaaca aagggttttc tagctaaggc taaggaaaat aatattggta tgactgctaa
   217381 tgttgtaggt ggtatgtttg gtttattttt tacggatgct aaatcagtga ctaattttaa
   217441 agaagtttct cagtgtaatg ttgaattgtt taaaagattc tatcatctaa tgttggaaga
   217501 gggggtgtat atgacacctt ctatttatga aacagatttt atttctagtg ctcatagcga
   217561 tatggatatt caaaatacta ttgatgcagc tggacgcgta tttgcaaaat tggtataaat
   217621 tcttatgaag attgatgtga ttaagtctta attgatcaat actactaagt tactggataa
   217681 ttttagtaac aatattacta taccccataa gaaatagcat gatttaataa aaaagtttat
   217741 ttattgagta aattattatt tgataataga ttaccaagtt tatgcaagtt gcaaattagg
   217801 ataattgaat aagtgttaaa atttaaatta cccaatgaat aatatttcaa cctatatttg
   217861 aatgagtggt acattatttg agtatctttt tgatactaaa gttatattga tcaacaagat
   217921 ttaattctat tatggaggta ataaaaacac taatcagtgt taagaaaatg taatgacact
   217981 tgcaattttt gatttagaca gaactctcat taagggcgat agtgactttc tttggggaga
   218041 atttttaagt gaaattggtg ctgttgatgt aaatatttat cagagtaaaa atcagtattt
   218101 ttttgatcaa tatatgctta gaaagttaga tattcatgag tatttagaat tttgtttaga
   218161 acctttatct aaatactcta tggaaatatt aaatcaatgg catcagtggt ttatggacca
   218221 aaaaattgag caaattttac tacctaaagc tcaattagtg gtcgataaac ataaagaaaa
   218281 aggtgataca ttgatggtga ttacgtctac taatcgcttt gttactgaac cgattgtggc
   218341 tagatatggc attaagcatc tactagccac taatcctgaa ataaaagaag gtcaatatac
   218401 aggtaaagtt aagggtgaac cgtgtttcca atttggaaaa attaatcatc ttaacaagtg
   218461 gttgaaaaaa actagtttaa gtattaaagg tgcaagtttt tattcagatt cttataatga
   218521 tttaccaatg ttggaattag tagattatcc tattgttgtc catggtgacg ataaacttaa
   218581 tgccattgca attgagagag gttggagatg tttagattgg acataatgtt ttttataaaa
   218641 agtacgaact gttgtttatt ttagaaagca caaaaacctc cttttagagg aaaggttttt
   218701 gttgatgggt aaacagagtt attacatata aagattatgg tttgagtcat tacattcctc
   218761 aaagtaagtg gctgcacctg caaattcgac accatcaatg aagtcatctt tgctgtaacc
   218821 aaataaatca accgtcattt cacaagcgat aaatttaaca tcaaattcct gacacataga
   218881 acgtagttca tcaagcgttg caaccccgtt tttcttcatg gttttcttca ttaaataagt
   218941 ggctaaatgt tctgtaaatg gcaataacca aaatatattt gggattttag ggctaaaatc
   219001 aattttctgt aaccattccg gccctatagg tagtttcatt ggcatggctg gattacctat
   219061 aggagatata cgtaatttag aggtgtcttt taataaaaga ttaagcccgt aaaaggtaaa
   219121 aaatatggta acttctttat ccattgcaac accagtagaa gcgataatga aaggtggaaa
   219181 ggcccaatca aaagttcctt tagtagcgat aatagtcatt tttttattat ctgacataat
   219241 gattctcctg taaaatattt agtgtttaag tcttttcaat ggtgaagata tatttaccac
   219301 tttcttcaac agcagacata agtttattac ctgtttgatt gcaaaaagct tcaatatctt
   219361 ttactgaacc agcatcagtt gaaattacgt ctaaaatctt gcctatatcc attttagata
   219421 atgccttttt agtttttaaa attggtaatg ggcagtttaa gcctgatgca tctaaagttt
   219481 cgtcagccat ttgtgaactc cttatatttt ttaaagttta aaataatgaa catattagaa
   219541 ataactaata agttacacta ttttagtctt ccatcagtaa agagtcaaat ataataagcg
   219601 tatgattgaa tatttagtaa aatatgtatt gataatttta ttcatgtttg tattagatgt
   219661 gtcttagtcg tccttttaag ttgttataag aacagaaata ggagtaatga tttttatata
   219721 ttatttgaga tagcagtttt gtggtatcta atattaaaat tcaggtttat ttaaaaatgt
   219781 taggatatga attttttgtt tatagtgaga attcatctaa gaatcttaat gttttatatg
   219841 ttgatattat taatcttgct tgtgagtata agtagaagaa gacctaataa atactaagat
   219901 gctattaaga tctggcttta gtcctaaaaa tatgtcatat tttttgaaaa atttaaagat
   219961 aatctagatg taaaaaattt tccgtactta tatatattgg tattaataga atttttgctt
   220021 gtgttgttgt taatataaga gcgttatatt ggaaataaag tgtttaacta tgatgtttcg
   220081 gggaaataaa aagtatcaaa aggctaaaaa tcatgtttga caaacctttg ttacctaata
   220141 cgtaacaatc taacataggt atttactatt ctcatgaatt atgtgataga tcctataaag
   220201 acaaggtaag tgagaatatt attcgttatc agtgaataaa acttatcatc ctagataaaa
   220261 tgattaattt gatatattgg taagttaaca ttgagtgttt agaaaaattg atagagttat
   220321 atcgattttt gttcaattaa ttggttatta tttttacgcc atttggtgta cctagtaata
   220381 aaacgtttgc accacgatta gcaaagagtc cattggttac tacgccaata atactgttta
   220441 attttgtttc cattgctttt ggattagtga ttttcagatc tttaatatca agaataaaat
   220501 taccattatc agtgataaag tcttttctaa cttcaggtat accaccaatt ttttggctta
   220561 tctgattttt aacataatta gctgccattg gaataacctc aataggtagt ggaaaactac
   220621 ccataatcga aactaatttt gattcatcgg caatgcaaat aaattgatga gccactgctg
   220681 caacaatttt ttctcgtgtt agtgcaccac caccaccttt tataaggttt aaattattgt
   220741 ctgattcatc agcaccatca atgtaagttg aaatggctgt tactttatta aggtcaaata
   220801 ctctaatacc atgattttct aaacgctgtg cagttgcttt agaacttgca acagctccct
   220861 taatattgtt ttttatagtg gatagcgcat caataaaaaa attagcagta gagccggttc
   220921 ctacgcctat aatggtattt tttattacgt acttgagcgc ggtttgtgct acagtgaatt
   220981 tcatttcgtc ttgagtcata atgagttcca tggaatctaa tattaggcta aattatacac
   221041 gatgaaaaag attattcttg ctagcaataa ccaaggcaaa atcaaagagt ttaataccat
   221101 gttaagaggt atttatcagg ttatatccat gaaggataag cagattaaag aggttccaga
   221161 agtaggacta acctttgttg aaaatgcact aattaaagca cgaaattcta gcgaacagtc
   221221 tgggttacca gcattggctg atgattcagg tattgtaatt gacgcattgg gcggtaatcc
   221281 tggtatttat tctgcacgtt atgcgaattg tcatggggat gatgaggcaa atattcaaaa
   221341 agtattaatt gatatgaagg acgtagtaga tggtgagaga actggacgat tttggtgtgc
   221401 tattgttttt gttgaatatg ccagtgatcc aacgcctatt atcattcaac aaagctggga
   221461 aggcgagata ttgcgtgaaa aaataggtaa taatggtttt ggttatgacc caatttttta
   221521 tgtgccaatc tataattgca cttctgctga gctttcattt gtaacaaaga acaaaatctc
   221581 tcaccgagga aaggctttat cggcgttgct taaagtactc aaaaaaaatt agtgagttac
   221641 acactagaat taccgccatt atcgttatat attcattatc catggtgtgt caaaaaatgt
   221701 ccttattgtg attttaattc tcatgattgc aatcaacgaa gtggctatat tgagtcgtta
   221761 ttagaagatc ttaatgagga cttagattat attcaaggtc gtgccattca atctattttt
   221821 ttaggtggtg gcacacctag tttaatgagc gagcaagaac tttttaagtt atttactggt
   221881 ttaaaaaaga ggttgaaatt tgtaaatgat attgaaatta cgttagaaac taatcctggt
   221941 atttttgaaa ttgaaaagtt caaattattt aagcatattg gtattaatag gctttcaatt
   222001 ggcgtgcagt cttttaatga tagacatctg caatcattag gtcgtattca taatgctgat
   222061 gaagcgattt atgcctgtaa acaagctaat caggtaggct ttaaatattt taatattgat
   222121 attatgtatg gattagagag acaaacatta gatgaatgtt tatctgatgt tcgccaagct
   222181 atgaatttaa aacctgacca tatttctttt tatcaattaa ctattgagcc taatacttat
   222241 tttgctaaat atacgccgat cttgccaagt gatgaggttg tttggcagat gggtgatgca
   222301 ggtgtaagtt tattagaaag aaatggttat acacgttacg aagtgtctgc ttttggaaaa
   222361 acaccttcaa agcataattt aaattattgg caatttggtg attatgttgg tataggtgct
   222421 ggtgctcatg gaaaaattac tttattaaaa gagtctttcc cgtttagaac gataaaggca
   222481 cgtttgccaa aggactatct aaaaaacagg caaaaacaag ttaatcagat taaaaattta
   222541 aattttgatt ttatgcttaa tgcactgagg ttaaaacatg gatttaattt gagattgttt
   222601 gagttaagaa caaggcaacc aatacaagta attgaatgtc aattaaataa ggcaaaagca
   222661 cttggtttat ttgaattgga tggcaagctg gcgaaaccta gtaaaaaagg tttcgatttt
   222721 ttgaatgatt tacaagctat ttttttatga tgtatttttt tggcattatt attcatttgt
   222781 ttgatactac ctagtaaatg cttaatctat tcattacttt attccatttt atggtatagg
   222841 ttaatacaat attatgtcag taaataatat gtacatttga tatgatgcta atacgattta
   222901 tggtttttat aataatctaa atactaatta gtttatagtg tttagcgctt atatttatat
   222961 ttatttgaat aatcctatta tgatattctt ctctaatcgt ttgatttttc tttagataag
   223021 tagtctaaag taataaactt tatggtatct attactgttt gatttattat tagataaata
   223081 ttgaagttta aaagatatta aataaataaa taatacttct tattgagaaa ataagattga
   223141 ttataaatat atattttgga gaaagaatac tagttaatgg ctttttagag tttatgaatt
   223201 aatactaact ggagaagtca atactagtta agaaaaatat tggtgatgag attacaatca
   223261 gatttatcag taaaactagt ttttgtttat ttttacttgt attaacaaaa atacagtatt
   223321 ttttatatta ttgaaatagt gcttcaagtc tcatagttat tattgaatag ataaaatctc
   223381 aaggtttact tatcaactat ttattatatt atgaacacaa tatctagtgt cttccggtat
   223441 tttatatttt ttatatggca tattatttaa ttcaatgatt ttaggtgtgg taatctcaat
   223501 gttattattc actgtaattt aataatgcta ataggttaag acatatcaaa attagtgttc
   223561 atttctggaa ttatttgggg ttttgtttgt caaaaaatta tattcttgct acaaacatta
   223621 agtaaaatat tattttaata aatttttatg ttgcataaca tgtctaataa catacacaat
   223681 attgcaagcg ttttaacgga aagcttatct tattttcaaa aattccaagg taaaaccatt
   223741 gttattaaat atggtggtaa tgctatggtt gatgaggcat taaaatctag ttttgcgcgt
   223801 gatattgtgc tgatgaaatc tgttggcatg aatccaattg tggtgcatgg tggcggccca
   223861 caaattggta agatattaga gaaaattggt aaacaaagtc aatttattga tggcatgcgt
   223921 gttactgatt cagaaactat ggatgtagtt gaaatggtgt taggcggttt ggttaataaa
   223981 gaaattgtca atcttattca tcagcatggc ggtcattcta ttggcttaac tggcaaagat
   224041 ggtagcttaa tttctgctaa gaaattaaaa agtgatatta aacctgaact aacgtctgaa
   224101 attattgacc ttggtcatgt tggagaggta gataaaattg atatttcagt gattaattta
   224161 ctattaaaag gggattttat tccagtcatt gcacctattg gtgtgggtaa ggatggtttt
   224221 tcttataata ttaacgcaga tttagttgca ggttcaattg ctcaagcgtt gaatgctgag
   224281 aagttaatat tattaacgaa cacatctggt ttattagatg caaatggtga attattaact
   224341 gggcttgacg tcaatattat tgatagtctt attgaaaatg gaacaattta tggtggtatg
   224401 ttgccaaaaa ttgattgtgc tctatcatct gttagaaatg gggtaaaatc tacgcatatt
   224461 attgatggac gagttgcaca tgcggtattg ttagaaatct ttacagataa tggtgttggt
   224521 actttgatta cctgtaatga atctggtaca ttgattactt ataatgaaca aggctagtcg
   224581 taatcaaatt aaggtttgtg attgtcaaat tttggctcat tctcggttcg agaatgagca
   224641 atatatttta actttatcat caagtgttat tgctcaacag agtaaaccag ggcaatttgt
   224701 acatcttaga gtttctgatt ttttagcaat gagacggcct atttcaatca tgttggttga
   224761 ttctgaaaag ggtacctttg acttgcttta caaggtggtt ggcaaaggta ctcgtcaatt
   224821 agctaagcaa aaagtaggtg atgtgctatc aatcattggc cctattggta atagttttga
   224881 gttaaccaat aaaaaacgac cactactaat tgggggtggt gtgggtatgc cgcctatgat
   224941 tgctattgca caacaaataa aaaatagtga ttataaatct tttgcaattt taggttcaga
   225001 agtgccattc ccattttccg ctaagttagc caataatggc aaagattatc agggtgcaac
   225061 gcatactatg acagagttag aggattgggg tattgagtgt cgattagcca gttttcaagg
   225121 ttttgatggt gtatttaagg gttttgtaac tgatttagct aaagtatatt tagatagttt
   225181 gacagttgat gaaataatgc aagttgaggt gtatgcctgt ggtccacatt ctatgctagt
   225241 aacagtggct agtttgatta aagagtatga tttgccttgt caggtttcat tagaggaaaa
   225301 catggcctgt gctgttggtg gttgcgcagg atgtgtagtt gaagttcaaa ctgaacaagg
   225361 tatttccatg cagcgtattt gtgttgatgg tccagtgttt gatgcctatc aagtattttg
   225421 attaaagata acttaataaa agtccagtta agaattagtc aggttaatca tactcagtct
   225481 gttactttag ttgcggtgag taaaaccaga tcagtatatg agttgcaaca agcaattgat
   225541 gtaggacaac agcattttgc tgaaaactat cttcaagaag cacttataaa aattaaccac
   225601 ttaaaaggtc aaaacttaat ttggcatttt attggtccta ttcagtcaaa taaaacctta
   225661 aaaattgcca aaaattttga ctgggtacac agtataggtc gattaaaaat tgcacaaaga
   225721 cttaacgatc aacgcccaaa aaacttacct aaattaaagg tacttttaca gattaacatt
   225781 gataatgaac ctactaaatc aggagtattg gttggacaga ttgatgaact aattactcat
   225841 tttgaaagtt taaaaaatct cactttaaga ggttttatgt gtgtgccaaa tccttttagc
   225901 tcagcacaaa gtttttctag aatggaaaat attatcaagc aatattctaa tttagatgtt
   225961 ttatcgatgg gtatgagtca tgatttagag ttagctattg aaaatggtgc tacttctgta
   226021 cgtattggtg cagatatttt tggaaaaaga acttgaatat aattatgttc attattaaat
   226081 gaagtatttt ataacttttt ttagaaaagg aatatggtta aaatttaatg ttttaatttc
   226141 tataaataaa tattttagat aaactgtctt ttttactttt gaataatata aatttatttt
   226201 actatattta agtttaaaca cagcatgatc ttgttatgag aattaaatta ttaattactg
   226261 gtggtacaat tgataaagtt tatgacgagt tgattggtca gttagtgttt caacgaacct
   226321 atctcattga tatgcttaat cggtctaggt cgatggttga tactttatct gaggtgttgt
   226381 ttttaaaaga tagtttagat atgagcgata ttgatcgagc gttgattgtg aaaaagtgtc
   226441 aggaaagtga cacaagccat attttaatca ctcatggtac tgattctatg attagaactg
   226501 caaaattatt agccaaagag attaataata aaactattgt tttgtttgga tccatgatcc
   226561 cttattctat taattgttct gatgcactgt ttaatttagg cgtagcttta agtgcagtac
   226621 aaatcaaaga atatggtgtt tatattacta tgaatgggca agtgtttgat tttgacaagg
   226681 tagaaaaaaa caaagagata ggtattttta cattgctata gtacttcgaa tgtaatcaat
   226741 ggtatttgtt ttatcgtata ttcagatgac tacttttagc taattatgtg aataaattca
   226801 tgtaagtact tttttggtaa cgtcaaatca ttttttaaat atacttagtc ctgttggact
   226861 aactttatgt ttaattgttt aattgaataa ctagaaaacg cattaacata aataataaga
   226921 atatacatta ttaaaattta cgtaactttt taagtacata ttttttctta tatttttaat
   226981 atagctttgt atcaatatca ataaataact catttgtaaa aataagttat aatttcttaa
   227041 ggtcggtgtt atattgagaa tgcatcgata agtataatga tgattaaaag aacacttttg
   227101 ggcggtacta aagtattaaa aataagcact tgggttagtg ttattttttc gctcattatt
   227161 gtactaatag tagtactttt tgtaacattt ccaatattat taaaagcgcc gattgaaaac
   227221 caattgtcaa gtttaactgg tcttgatgtt cggttatcta aaattacatt ttattttgaa
   227281 aatataggaa tcgccttaca agtacatgat attgctatct tatcaaataa aaatcagcag
   227341 aaagtagcta ttattaagaa attatcttgg catgtgaatt tattaaattt atttgataat
   227401 atttatcatt ctagcaaaat ttatattgat actttaatgc ttttttctaa ttctggtaat
   227461 gttaacataa ataatattaa caatatagtc tcacttgata tgttagaaaa gctatatttc
   227521 tttgaatctt tacatgtcaa taaaataatt attaagcatg caattaaaat tacgcctttg
   227581 actcttaaaa gggatggagt acagttctta ttgacaattc ctagacagga tcttgtaact
   227641 aaatatttta atgttacatt ttctttatct aatgttcaag taagtcgtga tggttgttta
   227701 acactgccaa ttactgtgat taataatgac tttaaacttg tattaggcct taagctatat
   227761 aaccagaaaa atgatgattt tatccagatt actggtctta tcaaacgtat gaatgtagtt
   227821 aaaattagtg attatttacc tgtagtatta ataggtagtg cgacttatca atggatcaaa
   227881 caagcatttc aatcaggtac gatagataat attaatattg atattaagaa gaatctttca
   227941 aaggagttgc cagcaaagat aaaaattaat gcacacttaa ctaataccga gctattgttt
   228001 aatgctgatt ggcacaatct taaacagtta gatgcaaata tttatattga cgataagcaa
   228061 attacagtta cagtcaatca cactatgtta aatgaaatgt ttttgcaaga tatcaaagtt
   228121 caaatgctgg atatgagtaa agataaatta gaagttagtg tggttggtaa aattaacagc
   228181 tatagcgaag tgttgactcg gtttttaaaa gaggtaccac tagatagtaa cttgaataat
   228241 atactaaact attttagttt atctggtaag gtaattgctg atgtggagtt aacaatacca
   228301 ctaaataaaa cagacctgac attagatatt gatttgaata ttgaagacaa tcatttgacc
   228361 atattgggcg gtgcaattgt tattaagaac tataatgcac atttagtatt acataataat
   228421 caaattattt catatggtat gggtaatatt cgaggtaagt cgtttaatat tcatatcaat
   228481 tctaataatc aagatagcgg tttagatgta ttatttgcgg tagtacttac caatagtagt
   228541 gataattttg agtttcactt agctaaatat ttaaatcaat catggcaggt aaatattaag
   228601 tctgatgcat taaaaactga tgcaaagatt atactaaatg atggcgtttt gcctgaagta
   228661 aaattaacaa atcttcaagt aacaggacta gataagataa aaggtaattg ggatattagg
   228721 gtaaatgata tccctagtat gcatttaagt gtacaagaca tacaaatagg tgaaaagaag
   228781 ctacctaatt ttcatgccac gcttgaatca caagacaaaa tgctaaaaat tattaattta
   228841 gaattttcag gtgttggttt tggtgctcaa aatctgagtt ttaatggtgt ttggattaat
   228901 ggcagaacta agctttttgc taaagtaaaa ggtaataaat tgagtgaatt tcttgataaa
   228961 ctaaatatta aagagaaggt tcgtggtggt caatttgagt ttgatgtgcg tctattctgt
   229021 aattgtgctc cgtggaacat gagttctgaa gatattagtg gtttgattaa agttaaagtt
   229081 aaagagggtg tatttactaa tgaagaccct aatattggtt tagttttatc attactgaat
   229141 attaaatcca ttgctaagcg tttggaacta aatattactg atttaattag taaagggttt
   229201 gcttatgata caattgatgc acaaatttat attaacaatt ctatggcgac tattgttcat
   229261 tttgaactta attcaagctc aagtataatt accttaacag gttcaagtaa attcgttgaa
   229321 caaacctatc atttagaggc aaaggtatta cctgctatta gtgatgccgt accgattgct
   229381 acttatttag ctggcggtgg cttagcaggt ttaggagttt ggttaacaga taagatgtta
   229441 tttaaaggag aactgattaa taatattgtt gataaagttg ttgaatttaa atataaaata
   229501 acaggtccat ggaataagcc tgttattgag aagatatcaa ctgtactatg attgaacaac
   229561 tattggatga tcaccattta aatcaagaaa taataaccac tttattatcc tctttagcag
   229621 ttaaaggtac tgattatgca gatttatatt ttcaacattc agcggttgaa tcttggtttt
   229681 tggaagaaag tattgttaag tctggtacct accatatcag ccatggcgta ggtgctagag
   229741 ctgtaagttt tgatcaaact ggttttgctt attcagatga tttaaaccta aggtcgattg
   229801 aaaaagctat taattttgcc aagggtgtat caatgtatca gactgctgta ggaaaaattc
   229861 aggattttca acctattcca caagttgcta aatatagtgg tttgaaccca cttaatagtt
   229921 tcagttcaca agaaaaggtt gattttttaa atagaattga taagattgct agaaaggagt
   229981 ctaaggttac acaagttagt gcttctattt ctggtgggtt tagtgaggta ttaattactt
   230041 caactgatgg tgtatttgct aaagattatc gcccaatggt acgtgttagt gtaaatgtta
   230101 ttgttgagtg caatggtaga attgaatctg cctcaagcgg tggtggtggt cggtatgatt
   230161 atcaatactt tgttaatcac gctttggatg aaatttatgt taatgaagct attagacagg
   230221 cattattagc gctggagtca aagaatgcac ctgctggaag catgccagtg atactgggtt
   230281 ctggctggcc aggggtattg ttgcatgagg ctattggtca tggcttagaa ggtgatttta
   230341 atcgtaaaaa atcatcagta tttactaata gaattggtga gcaagtcgcc agtgataaat
   230401 gcactattgt tgataatgga actttggcaa atagacgtgg tagcttgaca attgatgatg
   230461 aaggtacacc aacacaaaac actttattga tcgaaaatgg tattttaaaa ggctatctat
   230521 ttgataaaat taatgctaaa ttaatggata ctgtatcaac aggtaatggt agacgtgagt
   230581 cttatgctca tattcccatg ccaagaatga ctaatactta tatgttaaat ggacaagatt
   230641 ctttagatga tatgattgct tctgttgatt atggtattta tgctattaat tttgatggtg
   230701 gtcaagttga tattacttca ggtaaatttg tttttagtgc taatgaggct tatctaatta
   230761 aaaatggaaa aattatgcac cctgttaaag gagtgacatt gataggttct ggcgataagg
   230821 tattaaaaaa aatatctatg gtggcgaatg atttaaaact tgataatggt gttggtatat
   230881 gcggcaagga tggccaaaac gtacctgttg gagtgggtca acctagtcta aaaatagacc
   230941 agttgacagt aggtggcact gaggttaatg tataatctaa cctctaaaaa tgtatttggg
   231001 gttataggta agtttgtcaa tttaattaga tataatattc agaagtctat tttttagttg
   231061 ggagaaatta ggtgttagaa aattatttac ctattgttgt atttatattt ttaggacttt
   231121 tttttggtat tgggccaatg ttaattggct atttactagg tccgagtaaa ccaaatgaag
   231181 aaaaaaatac tcaatttgag tgtggttttc ctgcctttaa tgattcgcgt acgtatttta
   231241 atatacgtta ttatttagta gctattctat ttattttgtt tgatttagaa gttgcctttg
   231301 tttttccgtg ggcggtagtt cagtcccaac ttggttggtt tggttttgtt gtaatgagca
   231361 ttttcttatt tttattgata gtgggttttg tttttgagtg gaaaaacggt gcacttgaat
   231421 gggaataact aatggcaatt gagggtttaa taaaacaagg ttttgtaacc atgtcgcttg
   231481 acagagttat taattgggca cgaacaggtt cgctttggcc aatgactttt ggcttggctt
   231541 gttgcgcggt agagatgatg gaagcaggtt cttctcgtta tgatttagat cgttttggta
   231601 ttgtttttag gcctacacca cgtcaatcag atttaatgat tgtagcagga acacttacca
   231661 ataaaatggc tccagcttta cgcaaagttt atgaccaaat gcctgagcca aagtgggtta
   231721 tttctatggg gtcatgtgcg aatggcggtg gttattatca ttactcttat gcagttatta
   231781 gaggttgtga tcgtattgtt ccagttgata tttatgttcc aggttgtcct ccaacggcag
   231841 aagcattgct atacggcatt atgcaattgc aagataaaat tcgacgtact aacactattg
   231901 cgagaacata atgcaagatt taaagacatc attagttgag gtttttggaa agaccaattt
   231961 ggttgaatct tttgatgagt taactttaac agttggttct cagaatatta ttaaaacctg
   232021 tttaaaatta agagattttt tctcttttga cacgttaata gatttatgtg gtgttgatta
   232081 tttaacttat ggacaatcag attggaatgg caatgctagt gcttctggtt tttctagagg
   232141 acgtagtcat caagggttaa aagatataca tgaagagcgt tttgctgtgg tatatcattt
   232201 gttatctgtc agtaaaaaca aacgtattag agtaaaatca tttgttgatg aagtggagcc
   232261 tattatcaag tcagtcactg atatttgggc atctgctgat tggtatgaac gagaggcctt
   232321 tgatttaatg ggtatcttgt ttgaaaatca tacagattta cgtcgaattt tgactgatta
   232381 tggctttaca ggtcatccat tacgtaaaga ttttcccatg attggtgaag ttgaaatgcg
   232441 ttatgatgag gatttgtgtc gggtgattta tgaaaaagta agcattgaac caaatgttaa
   232501 tgtgccaaga gtaattagga aataaaatgt ctgaaattcg taattatact cttaattttg
   232561 gtcctcaaca tcctgcagcc catggtgtac tacgccttat tttggaaatt gatggtgagg
   232621 ttattgagcg ggctgacccg catattggct tgttacaccg tggtacagaa aaattggtag
   232681 aatctaaacc atataatcaa tcaattggtt acatggatag gcttgattat gtttcaatga
   232741 tgtgcaatga acatgcttat gtgatggcaa ttgaagctat gttgaattta aaagtaccta
   232801 aacgtgccca gtacattcga gtaatgtttg acgaaattac tagaattctt aatcatttga
   232861 tgtggttagg cacacatgga cttgatgttg gggctatgag tattttttta tatgcatttc
   232921 gtgaacgtga aaaattgatt gattgttatg aggcagtatc aggttcacgc atgcatgcaa
   232981 cttattatcg tccaggtggt gtttatcgag atttgccaga taaaatgcct cagtatctag
   233041 cctcagattt tcgaacaagt aaagagttag aaactatgaa cgaaaatcgt caaggctcat
   233101 tattagattt tattgctgat tttgttaaag aatttcctaa aagcattaag caatatgatg
   233161 atctattaac tgataatcgt atttggaaac agcgtttggt gaatattggc gttgtttctg
   233221 cgaatcgtgc taaacagtta ggatttacag gtcctatgct tagaggttct ggtgtggagt
   233281 gggatttgag aaaaaatcaa ccttatgcag tttatgatca attaaagttt gatataccag
   233341 taggtatgac aggtgatagt tatgatcgct acttagtgcg tatggaagaa atgcgtcaat
   233401 caaattatat tattaaacaa tgtgttaagt ggttacgaga aaatccaggt gcagtgatga
   233461 gtgatgatca taaggtatca caacccaaac gtactaatat gaaaaatgat atggaatctt
   233521 taattcatca ctttaagtta tttactgaag gttattgttt gccagagggc gaagtttatc
   233581 gtgctgttga gcacccaaag ggtgaatttg gggtgtatct tatttctgat ggagctaata
   233641 agccttatag agttaaaatt agagcgcctg gtttctctca tttagctgct atgaatgaaa
   233701 tgacaagagg acatatgttg tcagatgttg tgactattat tggcacacaa gatgttgtat
   233761 ttggtgaaat agatagatga tttcaattag agcaaaaaat caaattgatg tttggattgc
   233821 aaaatatcca aaagacagac aaagttccgc tgttatgcaa gctttaaaaa ttgttcaagc
   233881 agaaaataaa aatatattaa gtgctagtat tatccaagaa gttgctgatt atttagatat
   233941 gccagatatt gttgttcaag aagtagcgac tttttatgaa aattacaatt ataaaaaagt
   234001 tggcaagtat gtaattcgtt tttgtcataa tatttcatgt atgttaaatg gtgctgatga
   234061 tttaattaag catttagaaa ataaattggg tgttaaaaca ggtgaagtaa ccttagatgg
   234121 tttaatcagt gttaaaaaag ttgagtgttt gggggcttgt gtgggtgctc caatgtttca
   234181 aattaatgaa aagtattttg aaaaccttac tattgataag attgataaga ttgtggataa
   234241 tcttaaatga acgaagtttg ttttaaaaat ttgaaaaaag atcaatgttg gtcacttaaa
   234301 atttatgagg ctagtggtgg ttattcatca tggcgtaaaa tccttaaagg tgaattgaca
   234361 cctgagcaaa tcattgatga attaaagttg tcaggtttgc gtggtcgtgg tggtgctgga
   234421 tttcctactg gacttaaatg gagttttatg ccacgtcatt ctgatggaca aaaatacgta
   234481 gtttgtaatt cagatgaagg agaaccaggc acttgtaaag atagagatat tttaagattt
   234541 aatcctcatg cagtaattga aggtatggca attggtggtt ttgttatgaa tgctagtgtt
   234601 ggttataact atattcgtgg ggaatttatg gagccattca agcgttttga gagtgcgtta
   234661 gaagaggctt acaaggcagg attgttaggt caaaatatca ataacagttc gattaatttt
   234721 gatttatata cacacctagg tgcaggtgct tatatttgtg gtgaagaaac tgctttatta
   234781 gaatccattg aaggtaaaaa aggtcagcct agatttaagc caccatttcc tgctaatgta
   234841 gggttatttg gtaaacctac tacgattaat aatactgaaa gttttgcaag cgtgcctgaa
   234901 attttaagat gtggtggtca atggtttgca gatattggtg tggaaaactc tggaggttgt
   234961 aagttatttt cagtctcagg acatgttaca aatccagcaa attttgaagt acctatgggc
   235021 atatctttca aagatttact tgagatggca ggtggtatgc gtgacggcgc taagttaaaa
   235081 gccgtgattc caggtggttc atcaaccccg gtattaactg cagaaattgt aatgaatatg
   235141 actatggatt atgatggtat tgaaaaagca ggttcaatgc ttggtgcagg ttcagtgatt
   235201 gttatgaatg aatcaacttg catggtagaa gtattaacaa ggttggcgca tttctattat
   235261 gatgaatctt gcggacaatg cactccttgt cgtgaaggaa caggttggtt gtatagagta
   235321 ttaaagcgta ttattgatgg taatggtagg cagggagata ttgacttatt attaagtgta
   235381 caaaataaaa ttatgggtaa tactatttgt gcattaggtg acgctgcagc aatgcctgtt
   235441 gagagttttt tacgtaattt ccgtgaggaa tttgagtatt atattaaata tagaaagtct
   235501 atggttaagg gataattcga tgactgatat tgaaattaat attaacggta atattgtgag
   235561 tgctaaagca ggtgaaatgc taatcgttgt cactgataga gaaaatatta gtgtgccaag
   235621 attttgttat cataaaaaac tctcagtagt ttcttcttgt cggatatgtt tggtggatgt
   235681 tgagggtgtt cttaagccgc aaccagcttg ttcaacccca gttatacagg gtatgaaagt
   235741 tcagacacag aatgtaaaaa ctaagaatag tcagaaatca gttatggaat ttttacttat
   235801 taatcatccg cttgactgtc caatttgtga tcaaggtggt gagtgtgaat tacaagatat
   235861 ggctgttgaa tatggttcag atatttcttc tttttcagaa ggtaaacgca ttgtgacaga
   235921 tagtgatatt ggtgtgttga ttcaaacaga tatgacacgt tgtattcatt gtacacgttg
   235981 tgtacgtttt ggtgttgaaa ttgctggtat aatggaaatg ggtggaactg ggcgaggcga
   236041 gcatttaaag attgaaccat tcttagagca aggtattcag tctgaattat caggcaatat
   236101 gattgatatt tgtccagtag gagcgcttac ttctaagcca tttaaatatg agttaagatc
   236161 atggcagatg aactcaattc ctagtatcgc aaggcatgat ttagtaggtt caaatctatt
   236221 tgtacaaact tacaagggta aggtgaaacg ggttgtatct gctgataatg atttggttaa
   236281 tgaaatttgg atttctgatc gtgatcgctt ctcgtatgaa agtctaacgc atgagaatag
   236341 attgttaaaa cctcaaatta aagtacaagg acggtggaat caagtaagtt gggaagtggc
   236401 attggattat gctgtaaaag gacttaatag tcatatcttg aatcatcaaa aagccgatca
   236461 attaggtggt ttggtatcaa atacagcgac tatggaagag ttttatttat ttaaaaagat
   236521 tctaacagaa gttggttgtg acaatattga ctatcgttta aatgttaaaa acttagataa
   236581 tactattata cttgattcca atatcaaact agatgcacta gaaaagatag attatgcttt
   236641 aattataggg actaatattc gattagaaca accaatgatt aatcatcgtt tacgtaaagc
   236701 tacaaaaaaa ggtgcagata tcgatgtatt aaatgtaatg gtatttgatt ttaattattc
   236761 gcttcatact gaaaatatta ttgcaccaaa taaaatagca tttacattag caggcgttct
   236821 taagtcaatc atgattgaca atggtcaaga attacctgac tacttgatag ttattgatgt
   236881 tagtgaagtg gctaaaaata tagcttataa agtgttaaat tctgatagtt cagttattat
   236941 tttaggtgaa catattatta ataatgaaga cgcttctact attgctaatt tagttactaa
   237001 aattgctcaa agtaccaata gtagaacatt gaatttgagt ataacggcaa atactttagc
   237061 agctaattta gttgggtgtg tgccccaaaa ctctggtatg aatgttaata cgatgtttgt
   237121 gtctgatatg cgcggcttta ttttgttaga catttatcca cagtacaatt ttcatcattt
   237181 aggatcagct attaaagctt ttgaaaaaga taatactttt gttatttctt taaatagttt
   237241 taaagacgat atcgttgctg gttattcaga tgttattttg ccgatcgcta gtatttatga
   237301 aacatcagga acacatttaa atattaacaa tgatatgcaa tcctatacag ctgcagttaa
   237361 agcaccaaat gaggttaaac ctgcttggaa agttttaaaa gtcatggctg atttattaga
   237421 attaccagga ttcaattatg atgattctac tcaagttttg gctgaaatat cttatcaatc
   237481 acaggtaatt catactcgtg acataaagga taaccttgcc agtcaccata atggtattag
   237541 tataatttgg caaaactcgt cttatagcat tgacgctgta ttaagacaca gtggaacatt
   237601 acaaaaaacc aaaataggac agataaataa cgcttacatg aatcaaacaa gcgctaaaac
   237661 attaaaagta tcagttggtg ataaatattt aggtgtagtt gtggtaatta ctgatgcagt
   237721 agcagatgat tgtgtattta ttaatactaa tcaaacagct aatattcagg gacaagcata
   237781 atggaacttt ggcaaacttt tgtgaaaatg gtacatgcac tcgttccttg gttggatggt
   237841 acagtagcta ttattttaat aatttttatt aaagcaattg ctttgttaat accactaatg
   237901 ttagtggtag cctactttac ttatgctgaa cgtaaagtga ttggttatat gcaattacgt
   237961 atcggtccta atcgtgttgg tccaaaaggt tggttacaac ctattgccga tgctttaaag
   238021 ttaatgacta aggaaatcat ttttcctact aaagcaaata tttatttatt tttattagca
   238081 cctgtattag ctattgcacc tgctattgca gtatgggcag tgattccatt tgacgaaagt
   238141 atttatatta ctaatttaga tattagcttg ttgtatgttt tagcgattgg ttctatcggt
   238201 gtttacggta ttattttagc agggtgggcg tctaattcaa aatatccatt attaggcgcg
   238261 cttagaagtg cagcattgct agtttcgtac gaaattgtta ttggttttgc gctagtaaca
   238321 gttgttatga ttgctggtag tgtaaactta aacactattg ttcaagcaca gcaaggcgga
   238381 attatttatt ggtactttat tcctttattt cccataatga ttatcttttt tatctcatct
   238441 cttgtagaaa caaatcgtgc accttttgat gttgtagagg gcgaatcaga aattgttggc
   238501 ggtacgcatg ttgaatactc aggtatgacg tttgcagtat tttttctagc agaatatgct
   238561 aatatgattt tgatggcagt tctttctgtg ataatgttct ttggtggctg gcattctcct
   238621 tttgaggcta ttccttatct tgaaagtgta ttttcttgga tacctggtat gatttggcta
   238681 ttggcgaaaa cgactttttt catgttttta tatttatggg tacgtgctac ttttccacgc
   238741 tttagatatg atcaaattat gcacttatct tggaaggtat ttttaccaat tactattatt
   238801 tggatatttg ttgtggcatt gatgactcaa ttacaactta gtccgtggtt ttaagttaac
   238861 ataccttatg attaaaaaat taaataaatt aattaaaaac tttaccctaa atgaattacg
   238921 aactgggcta aaggttactg ctaaagagtt ggttaacaaa aaaattaccg tacaatttcc
   238981 agaagaaaga actccaatat cgccacgttt tagagggtta catgcgttac gtcgctatcc
   239041 aaatggtgag gagcgttgta ttgcttgtaa attgtgcgag gctgtttgtc ctgctaatgc
   239101 cattaccatt gaatctaaga tgcgtgatga tggcacacgt cgaaccaccc aatacgatat
   239161 tgatttattt aagtgtattt tttgcggatt ttgcgaagaa gcctgtcccg ttgatgcgat
   239221 tgttgagaca caaatttttg attatgtgtt tgagtcaagg caaggtagta ttatgactaa
   239281 agagcgtctt ttggaagtag gtagtcaaaa tgagcaagtc attaatcaaa ctaagtttga
   239341 agatgctaag tataaataaa agtagataat gggattcgaa caaataatat tttatatatt
   239401 ttcattttgg tttgttgtta gctctttggc gatgattttt tcacgtaatg cagcaaaggc
   239461 ggttttattt ttagtgttgg cattttttag cgctgccagc atttggattt tacttgaggc
   239521 tgaattttta gctattattt tgattttggt ttatgttggt gcagttatgg tgttattttt
   239581 atttgtgatt aagatgctta atattgataa atcaacaatc aaggcaagat tcactggata
   239641 tttaccgtta cggcttattg ttgctattat tattattatt gagatgagtt tagtgttagg
   239701 atctaatcaa tttgggttag atgtatttag cgtcccagag cgtcacagtg aagattatag
   239761 taatattact gtattggcaa tgcaaattta taccacctat gtttatccat ttgaacttgc
   239821 ggcagttttg ttacttattg caatcattgc tgctattaca ttagtacata gaaatgatac
   239881 aagccgcaaa aaacaatcta tttctgaaca agtgaatgtt caagctaaag atagggtgag
   239941 acttgtctca attattttac ctgataagaa ggagaaataa atggttagtc taagtgaata
   240001 tttaatacta agtagtacaa ttttttgtat tgggttagtg ggtatttttg ttaatcgtac
   240061 taatataatt acattattga tgtgtgtaga attaattctg gttgctgtta atactaattt
   240121 tgttgctttt tcgcattttt taggagatga agcaggacaa atttttgttt tctttatttt
   240181 gacggtagca gcatctgaag ttgctattgg tctagctatt ttaaccttat tatttagagg
   240241 tagtggatct attagtgttg atgttactaa caatttaaag ggttagtaat ggaaaaaatt
   240301 tacttaacaa ttgcactttc acctttagta ggtgcggtta ttgcaggatt ttttggtact
   240361 atgcttggta aaacagcaac acatacgttg actattttag gcttattaat ttcaactgta
   240421 ttatctctat atgtgtttaa ttatcatatt ttagatcggg gtgaagtgtt taatcaaaat
   240481 ctttatacct ggatacaaat taataattta aatattagtg ttggtttttt aattgataat
   240541 ttaacagcag tgatgctagt agttgtatct tttatctcac ttatggtaca tatttatact
   240601 attggttata tgtataatga tgcaggttat acgaagtttt ttagttatat ttcattgttt
   240661 acattttcaa tgttcatatt gataatgagt aataatttta tgcaactttt ttttggctgg
   240721 gaagcagttg gattggtttc atacttatta attggctttt ggcatcataa agaaagagcg
   240781 gtgcaagcaa atttaaaagc ttttttagtt aatcgcgtgg gtgattttgg ctttttatta
   240841 ggaattagtt tgatattggt atttagtggc tcgttggatt atgcggaggt atttttgagt
   240901 cttgaaaaga cgataggtca acagctttgg gggttagatc ttattactgt tatttgttta
   240961 ttgttatttg taggtgcaat gggaaaatct gcacaagtac cactacatgt ttggctacca
   241021 ggatcaatgg aaggtcctac cccgatttca gctttaattc atgcagccac tatggtaact
   241081 gcaggtattt tcatggtatc acgtatgtca cctatgtttg aactaagtga tattgcttta
   241141 acagtagtta tggttgtagg tgcaattact gctttgttta tgggattact cggtattgta
   241201 caaaatgata ttaaaaaagt ggttgcttat tcaactttgt cacaattggg ttatatgaca
   241261 gttgctttag gagttagtgc ttattcagtt gctatttttc atctaatgac acacgcattt
   241321 tttaaagcat tattattttt agttgcaggc tcagttattg ttgctatgca tcatcagcaa
   241381 gatattcgta agatgggtgg attgcgtaaa aaaatgccaa ttacttattg gactgcactt
   241441 attggcacat tggccctggt tggctttcca ggtttttcag gcttttattc aaaagatatg
   241501 attattgaag cagtgtattt ctcatcatta tcgtattcaa gttgggttta tgttgcagta
   241561 gtagtaggtg tatttattac ttctttttat tcattaagaa tgtttttttt ggtatttcat
   241621 ggagagtcta ggatagatgt acatactgtt actcatctgc atgagtctgc atcttcaatc
   241681 atatttccat taattgtatt agctattcca tctttaatga ttggatattt gacgattgaa
   241741 tttatgttgt ttaatggttg gttagataat gctattactg ttgcttcaag ccatatttct
   241801 atggctaaat tgaaatatga atttcacagt gcagcatcaa tgattcctca tgcgatacaa
   241861 actttaccat tttggatgat gataggcggt attgccactg cttggttatt ttcaatttat
   241921 aaagtgcagt gggctgactg ggtacaaaag aaatattatc gtactaatta tgtgcttgaa
   241981 tctttgtatg gttttgatcg ttttaatgat cttatttttg ttagtggtgt gaagaaatta
   242041 ggaaacttct tgtataaggt gtcagatatt agtttaattg ataagttatt agttaatggt
   242101 agtgctaaac tcattgtttt agttggtaaa attttacgtc tcattcaaac aggttatgtt
   242161 tatcactatg cttttttgat gatttttagt ttattaatta ttttaacttg ggtgttattt
   242221 acgggtgaaa acccattaat tgagctttaa ttatgggaat ttcgttactt agtttactaa
   242281 tttggttgcc aattttttct ggtgtattag ttatatttat tggtaacggt cgtgctaata
   242341 tagcacgttg ggtaagtctg atactttcaa tttttatttt cgttatatca ttaagtcttt
   242401 atacatcttt tgattcctca acacatttaa tgcagtttgt tgaaaaatcg tcttggatat
   242461 cacaatttaa tataaattat catattggcg tagatggtat ctctgtacca cttattattc
   242521 ttacaacctt ttcaacaatt ttagtcatta ttgcaggttg ggaagtggtt attaaaagat
   242581 gttcccacta tatggcggca tttttaatga tggagggttt gattatcggt gtattttctt
   242641 cattagacgc tattttgttc tatgtatttt gggaggcatc attaattcct atgttgttga
   242701 ttattggtat ttggggtgga gttaaccgtg tgtacgcgtc tattaagttt ttcctatata
   242761 cctttctagg ttcagtgttt atgttattat ctttaattta tatgtataac aaaggtggtt
   242821 cattttcaat cattgatatg cataacttaa aattaagttt tacggaacaa agctatattt
   242881 tttgggcatt ttttatggca tttgctgtta aagtgcctat gtttcctatg cacacttggc
   242941 taccagatgc gcatgtacaa gcgccaacag gtggttctgt tattttagct gcaattatgc
   243001 ttaaaatggg gggttatggt ttttttcgtt tttccctccc cattatacct gatgcttcat
   243061 tagagttttc agaaatcatg ataatattgt cacttattgc cattgtttat attggtttta
   243121 ttgcacttgt gcaacgtgat ataaaaaaac ttatagctta ttcttcaatc tcgcatatgg
   243181 gttttgtaac actaggtata tttaccttat ttttgagcta taagcaaaac ataatagaag
   243241 gatcattatt aggtcttgag ggtgctatgg tgcaaatgat ttcacatggt tttatctcag
   243301 ctgctatgtt tttggtagtt ggtgtgttgt atgatcgttt gcattcaaga gagatatcaa
   243361 cctatggggg tgtgattaat actatgccta aattcacagg atttgttata ttatttgcaa
   243421 tggctaatgt gggtttgcca ggtacttcag gatttgtagg agaatttatg gttatcttag
   243481 gcgctattca agcaaatatc tggtatggta tattatcggc aagcacattg attataggtg
   243541 cagcatatac attatggatg gtaaaaagag tattttttgg agttattact aatcctgctg
   243601 tatcaatgct aaaagatatt aatgctcgtg agttttcaat tcttgcaatt ttggcaatag
   243661 tagtattagt tattggctta tatccgcaac cagtgattga gttaatgcac atttcaattg
   243721 aacatttatt acaccaagct ttaacgtcta aactttaaat attgacttat gaataatctt
   243781 atcgaatttg acacatcatc tttatgggtt gtgttaccag aaatattttt actcagtgca
   243841 attatagtaa ttttattgtt agatttattt ttaaataaat attctcaaca agttacatat
   243901 tacctaaccc aactaagttt attaattagt ggattactaa cattcaattt aattgatcat
   243961 cctcaggtaa ttatttttag tggttcattc atactagata atatggcatc agtatttaaa
   244021 gtatttatga tgattgccac gatgattgct atggtttact cacgtcatta tttaagggca
   244081 cacttacttt ttaggagtga gtattttatt ctggttttat tatcaatact aggtatgatg
   244141 gtaatggtat ctggttatag tttattaaca ttatatctag ggttagaaat cttatctttg
   244201 tcattgtacg cattaattgc tattgcacat gaaaaggtat atgctattga agctgcattt
   244261 aagtacttta tattaggagc aatttcgtct gctttattgt tatacggtat gagtatgatt
   244321 tatggtatta gtggtagtct taatattaac gaaattgcta attttgtatc taatacagat
   244381 cttacttcaa gaaaaactct gattattaat tttggcttag tattcttagt tattggtatt
   244441 gcctttaaat taggttctgt tccttttcat atgtgggtac cagatgtcta tcaaggcgca
   244501 cccacttcag tcacactttt tatctcaact gtacctaaaa ttgcagcgat ttctatattg
   244561 atacgtattt tagttaatgg tctaggtagt atgcactcct attggtcaga tttatttatg
   244621 gtattgtcta ttttatctat tacactaggt tctgtagtgg cacttatgca aaccaacatc
   244681 aaacgtatgt tagcttattc aacaatttca catgttggtt ttatcatgct tggttttgtg
   244741 actggaacat taactggtta tagtgcagca atattttata tgttagtata tatactaatg
   244801 agtttggcag cctttggtat gattattcta ctgaataaac aaggttttga agtagatcaa
   244861 atttctgatt ttaaaggtct tagtaaacat tcaccatggt ttgcactaat gatgttaatt
   244921 gtcatgctat ctatggcagg tattcctcca ttgcttggtt tctattcaaa attctttatt
   244981 ctccaacaaa tagtatcagc tggctttata actattgcaa tttttgctgt tatttttgct
   245041 gttattagta cctattatta tttacaaatt attaaattta tgtattttga tgaaattgat
   245101 aacaatatat ctattaatgc atcaatagat atgcagttag ttttatcaat gaatgtcatt
   245161 ttaatacttg tagttggttt gttcccagat ttcttgatac aattagtact gtcactattt
   245221 taaactaaac cactgatata aagttttatt gtatatagtg ataattttat ctaaattact
   245281 agttagtaaa ggtgaatata ttttagaaaa aacaaggtgc tgttgctcaa ttatcttaat
   245341 taatttttta ttgggtttca agagtaatat tggcaatatt acttgtttgt ttccatgcat
   245401 gtccataaat tacttcgtaa gtgactggta attttccatt atttttgtaa gactcataca
   245461 ttttaatcat tagccggaac ttatttttac cagttagtga ttttgaacgt ttgataactg
   245521 tttgggcgcc aatagcctta agatcatgta ataagtcaat gactgtttga taagtaagtg
   245581 tccaagtttc catttccatt acaggatttt ggaatctatt ttgtaacatt tgatcaccaa
   245641 tatcatgcat atcaataaaa gtattgacat gtattttatc atctacaacc gaccagctat
   245701 tttttaattc tttgagtgtg tctggaccaa aggtagaaaa taaaaataat ccatcatttt
   245761 taagtacacg aaaacattct gagaataaag tattaagatc tggacaccac tgcatcatca
   245821 aattagaagt aattatatca atactattat ttagtagggg taaataatta gcattagcac
   245881 aaatcttgtt actagatggg ttgtatttta aggatttctg ggaaaagtct atgcaaataa
   245941 tttttgagtt caaaaagcac ttagttaact gtttgcttag taaaccagta cccgcaccaa
   246001 gatcaagaat gatatcagct ttggatgaaa tagtattaag tttcttatct aacctaatag
   246061 caatttcttt ttgtaataat gcgtgattat cgtaattatt tgaggcttta ttaaatgaaa
   246121 gtcttatttg agacattgaa taactttatt ggtaatatta tgcatcagtt taaaataatg
   246181 attagatttt tgttgaatat taaaacctat aatatcaata ttgactgaat ttatattcaa
   246241 acctttaatt agtggattag ttcgtttttt tgatatttct acagtagtga gtaaacattt
   246301 tgtttgtgta tttttcatta tttttttagc tttaagtatt ttagatatac ttaacctttc
   246361 tccgtggtaa ttcgtaatat tgattgattt ctttaattga ttagcattaa taaaataatc
   246421 aaaggtatta gaataacttg caagaatttt agacttgtaa aataataatt tttgatcaat
   246481 accttgtttt agtttgttta aatttttatt aagtttatct aaattatttg tgtaatttaa
   246541 ctggttattg ggatcaattt taatcaactt ttcaatcaat tcttttgcaa atatttgcat
   246601 attatttatg tctagccaaa gatgatagtt aattgttttt tgatgttcat caagttcgta
   246661 ctcattgtat tctttattat gaataagatg aatatcttct atattgccaa taattagttt
   246721 tttattatca ctaaggttat ttaatatttt tttaagccca ccttcaaggt taggatgaat
   246781 aaaaatagct aagtctgcgt ggcttaataa caataactgg gatggtttta gatgagtatg
   246841 atgtgctgat tgattggttg ttagtaataa ttttggcgtt gttattcctt gagttaagct
   246901 actaacaata gagtgaatag gtttaatact aactacaata tttggctctg caaagatatt
   246961 tgcagaaaat aatagtgttg ttaagagaga acgaacaatc ataattattt tttctaaaat
   247021 aaggaaataa ttatactgct caatttgttt ttaacaagca aaaattatac gtttaagtgc
   247081 tgtaaatccg gttattattc tggaacttga aaatttctca agagattgtg ttttatcgtt
   247141 attattttag gtatatctag gaacttaatg tttttaaatt ctgtatcgtc aaactaaaca
   247201 tgtagtgtat tttttaatga taagaaataa atatttctta ttttatcata gtatcctttt
   247261 aggactgttt tttaactttt ttctaatcat taataagcgt ttctagagat atttttctat
   247321 ttggattaat gatatttcct aatttcttaa atacaatctt ggtttttggt gatataaaat
   247381 atctgcataa tataccgtgt taaatgaaga ttttttagtt tttattctag gaataatggc
   247441 aatataagtg tgtttgttgg attgttaatt aacgtgtgaa taacttgaga atgataatta
   247501 aataataaga atgattcaat acttggtgta attttagtat gtgatatagt cgtaaatata
   247561 ggtatccatt atgaggacta catcaagcac agattcatct tttaagtggt cttaatatga
   247621 agaataatat accagtgaat taccaatctg ataggggtat ttatattaaa taataattta
   247681 tgttagcgat ttttataagg cgaaatcatt aagtttatga gaatcaatat ttaaataagg
   247741 tattataaat tataatatct tgcttttatt attgtttttt acatataaat atgcatggta
   247801 aataagttga agattaaatt taactgtatt gatatagtac atttataaaa attactcagc
   247861 ataaattcat gtaagaatag tgattctata ataagtagtt tataataaag attcaaaaaa
   247921 tgtggataag ttaatttttg aataatttgg aggtataaaa atgataagta aaatacttag
   247981 ttttgctata atatttgtat tagtaggtga tgtaatagct ggtggagatg atcgtgatat
   248041 gggtcttatt gaaccgattt ttaataaaat tgtagtgaag agtgagtaca atcttgatac
   248101 aatgacatta attgaaactt ctagtgtggt tgaacaaact gtagctgatt cttcagtgat
   248161 actagtagtg catgaagctt gcaaaaataa acttaattta ctgaatgtta acataaaaag
   248221 atttgaacaa gcgttagcta gtgatatttt gtacaataca ggtccaattg atgaaatggg
   248281 cacattattc tctcctgaga gatgggaaga ttattttatt tgcgtagaaa atcaccaaaa
   248341 ttaatgctta ttaatcaata aaagcccgat ataaaatgag ctttttattg attaatcatt
   248401 caaggttatt gattaaattt ctagtaaaga atcttctttt ttattaaggt taatttctat
   248461 ttttttaata tattcgtcag taattttttg aatatcgtat tctgcttttc tagcctcatc
   248521 ttttgaaatt tctttttctt ttaataattc tttaaaatca gaattggcat cacgacgaat
   248581 attgcggata gcaattttgg ctttttccgc ttcatctttg atgattttta ctagttcacc
   248641 tcgacgttct tgagtaagtg gtggtaaatg aatacgtatc acttgaccta tagtttgtgg
   248701 attaagtcct aaatctgatg tcataatggc tttttcaatt acagatacca tatccttttc
   248761 ccatggagat gccttaagtg ttcgtgaatc ctctgtactg atattagcta cttgagatag
   248821 gggcaccata gaaccataat aatttatatg aatttgttca agtaatgatg ggtgtgcacg
   248881 actagctcta attttactaa aagcattttt aagtgaattg atacttttat tcattttatt
   248941 ttgggaattt tgttgtattt catttaacat agtttatttc cttacaatag tgcctaaaag
   249001 tttccctttt aataagtctg acaatgtgtt ggtgttttct agcatactaa atacacaaat
   249061 ttctaaatca tgtttacgac atagtgcgaa tgcagatacg tccataattt gaagattttt
   249121 ttcaattgct tcgtcgaaac ttaatgaatt ataacgtttt gcatttggat ttttaacagg
   249181 gtcatcggta taaataccat ctactttagt ggctttaaat atagcatctg caccaatctc
   249241 aatagcgcgt aatgctgcac cagtgtcagt agtaaaacat ggattacctg tacctgcaca
   249301 aaaaataatg actttgcctt tttttaatgc ttgtttagcg tatatgtgat taatcgaatt
   249361 acatatacca ccacctattg acaagcctga catgaccaat gcatcaacct tatttttttg
   249421 acaagtatct gcaatagcaa gtgcattgat gatagttgat aacattccaa tatgatcact
   249481 agtaattcga tttatgccag tttttgtaag tgtttcacct ctaaaaatat tacccccacc
   249541 aataacaatg gctatttcaa tattttgact aagtactgac tttattatat caactatttt
   249601 atttagtgtt actgggtcaa ttatatttgt agtgctagcc aatgcttcac cactaagttt
   249661 taataagata cgtttgtatt tactcattat tgtgtgctga aaattataat atatggataa
   249721 ttttacctat ccttatgggt ataataaatc tttgtctgat atattttata tggatcaaat
   249781 tagtattcgt ggtgctagag ttcacaattt aaaaaatatc gatattgata ttcctagaaa
   249841 taaattgatt gtaattactg gactatctgg atcaggtaaa tcttcattag cttttgatac
   249901 tatttatgca gaaggacatc gtcgttatgt agagtcttta tcagcttatg cacgtcaatt
   249961 tttatcactc atggaaaaac ctgatgttga tcatattgaa gggttatctc cagctatctc
   250021 tattgagcaa aaatccactt cacataatcc acgctcaaca gttggtacaa ttactgaaat
   250081 ttatgactat ttaagattat tgtttgcacg tattggtatt cctatttgcc caaaacacaa
   250141 aattaatctt gaatctcaaa ccatttctca aatggttaat aatattgtta aattaccaat
   250201 tggtagaaaa attatgttgt tagcacctat tgttcagaac cgtaaaggta gccatgtaca
   250261 attattaaaa gagttaaatc agcaaggttt tttaagggct agaattgatg gtgtagttgt
   250321 gtatatagat gaaatggaag tattgaatag taaggttaat catagtattg aaattgtagt
   250381 tgatcgttta aaaatacgag aagatatgat ttcacgttta tctgaatcat tagaaactgc
   250441 acttaattta agcgcaggtt tggtacgcat tgcacctatg gaatatgaat catctttgca
   250501 agaaaaggta ttttccgcta agttttcttg tattgaatgc ggttactcat taagtgaatt
   250561 ggagcctagg cttttctcat ttaataatcc agttggtgct tgccaaactt gtgatggact
   250621 gggtgtgaga gatacatttg atgaacaaaa agttgtagtt agtcctagta tgagtttagc
   250681 agatggggca gtttatggtt ggggacgctc aaatgcttat ttttatcaaa tattaatgtt
   250741 agtaggtaag tattacggct ttagtattga aacaccttat gaacaattaa gtaataagca
   250801 caaaaaaatt gtcctttatg ggagtggcac agatgatatt gacttttcaa gaatcaaagg
   250861 acgtaagggt tggtctaata aagctaagcc atttgagggt attattccaa gaatgatgcg
   250921 tcgttatgaa acaagtgaga ttaatagcgt tagagaagag ctttctcgtt atgttgttag
   250981 taagaattgt actgaatgtc atggcgatag attaaatgaa tcagctagaa atgtgtttat
   251041 tgatgagcaa aatttatcaa atattactaa gctttctatt gctgatattt atagtttttt
   251101 aaaagaggta aagctggaag gagttcgtgg tcaaattgcg gaaaaaattt taaaagaaat
   251161 tattcaacgt ttagaatttt taattaatgt ggggttagag tatttaagtc ttgatcgtag
   251221 agcaaatagc ttatcaggtg gtgaggcaca gcgtattcgc ttagctagtc agattggtgc
   251281 aggattgatg ggtgtcttgt atgtacttga tgaaccatca ataggtttac atcaaagaga
   251341 caatcaaaag ctattaaaca cacttgccta tttgcgtgat attggaaata cagtgattat
   251401 gatagaacac gatgaagaag caattaaaca ggccgattat gtaattgata ttgggcctgg
   251461 tgctggtgta catggaggtg aaatagttgc tattggtata cctaaagata ttgaaaataa
   251521 tcttaagtct ttaacaggtg attatctaag tggtcgtcaa agtattaaag ttcctactaa
   251581 acgaaaaagt gccaatcaat ggattcgtat taaaggcgct aagggtaata gccttaataa
   251641 tgttgatttg tctattccta taggtgtgtt aacttgtgtg acaggcgtat ctggttctgg
   251701 aaaatcaacc ttaattaatg atactttgta tgctttggca gcaagggaac ttcatcatgc
   251761 acaaataaca cctgctgaat atgaatcagt cgaaggattg aattatcttg ataaaattgt
   251821 taatattgat caaagtccaa ttggacgtac accacgttct aatccagcta cttatacagg
   251881 tgtattttcg ttagtgcgtg atttattttc acaaacttta gaggcaaagt tacgtggtta
   251941 taaagcaggt cgttttagtt ttaatgttaa aggaggtagg tgtgaagcgt gcaagggtga
   252001 tggattgatt aaggtagaaa tgcatttcct atcagatatt tatgtatcat gtgatgtatg
   252061 tcaaggtcag cgttataatc aacaaacttt agaagtgttt tataaaggaa aaagcatttc
   252121 gcaggtactt ggtatgactg tagaacaggc aattaggttt ttccaatcta tttctaaaat
   252181 taaacaaaaa ctacaaactc taatggaggt tggactctct tatattactc ttgggcaaaa
   252241 tgcaactact ttatctggtg gtgaagcaca acgtattaaa ttagcaaagg aattgtcaag
   252301 aatggatact ggacgaacgc tttatattct tgatgagccg acaacgggtt tgcattttca
   252361 tgatattaaa cttttgttat cagttattaa tagattatgc gagcgtaaca atactattgt
   252421 tattattgaa cataaccttg atgttattaa aactgcagat tggattattg atttaggacc
   252481 tgagggaggt aataagggtg ggcagattat tgcatttggt acaccagaag aagtggcaca
   252541 agttaaggaa tcgtatacag gagaatattt aaaaacttac gtgtaattta tctttgattt
   252601 catttttaat ctgaaactag tttaatatgt atgtgttttt atatttatta gtactggttg
   252661 tgtgtaaaaa agattttata ttgttgttat tagcgggttt actctattaa ctttgatagt
   252721 tgaataaaac taaattagtt tgtattatac ttcaaatcat tttttctaat ttttgtctga
   252781 gttatggtat ggtaagaatg gatacaatat catgatcttt aactatctat aatttgatag
   252841 tgtatagaat tatcaccttg atgattggct aaaaagtaga accttttatt ttttataaag
   252901 gctaaaagta tataagttat agcttttttg gtgtaataat atatatttaa agttcgacgg
   252961 tgtatacttt aaaagtaata ttaataattg ctaattattt atgaataatt ctaaaataga
   253021 taagaaagtt agaatattat acgaactaat ttgataatat ttttccatct agtatagctt
   253081 gatttccttt aagttttagt ctgccttgtg taaaccaatg aataactttt gggaataatt
   253141 tatgctcctc aagtagaaca cgttttgcta aagtctcttt tgtatctgta tcaataatat
   253201 taatactagt ttgggcaata ataggacctc catcaagttg tctagttaca aagtgaatac
   253261 tcactccgtg ctgtttctct ttagcttcta tcactctttg gtgggtattt agtcctttaa
   253321 attttggtaa taacgaggga tgagtattaa gtatttttcc tgaatattga tgtgtaaatt
   253381 cagcgcttag tatacgcata aacccagcaa gaataataat ttcaggattg tattgattaa
   253441 taatattgct taacgcttgg tcaaattttt ctctagatga aaaattttta tgacttagtg
   253501 tatgagtagg aatattttca tgttcagaga gtttaagacc ataagcattg gtgtgattgc
   253561 taataaccgc tctaattttt aaatcgattg caatagaatg atcaattatt gattgtagat
   253621 ttgaaccatt gccagaaatt aaaacaacac cgttcatggt ttaatatgcg agttaaataa
   253681 taacttgatt accttgatta ttcttaattt cacctactaa ccaagcttgt tcgcctattt
   253741 cgtttaaata ttcaatggcg tcagcacttt gttcttctgg tacaataata atcatgccta
   253801 tgccacagtt aaatactcga tacatttcca tcatgtcaat attaccacta tcttgtaaaa
   253861 attgaaaaat actaggtagt tgccaagaat taacgtcaag ttttgcgctc aggtttttag
   253921 gaaatactct agggatgttt tccaataaac ccccacctgt aatatgtgaa atagcatgta
   253981 ctgagaattt tttaatcaat gataggattg atttcacata gattctagta ggtttaatta
   254041 gttcatttaa ttgttcatca gttgggtttg attgggctaa tactttgtgt attaatgagt
   254101 aaccattaga atgtggtcct gaagatgcta gagcaataat atggttacct atagtgactt
   254161 ttgtaccatt aattatctta tttttatcag taatacctac acaaaaacca acaaggtcgt
   254221 attcttcacc ttggtacatg cctggcattt cagctgtttc accgccaatt agagcacaac
   254281 ctgattgttt acaaccttca ccaataccat aaataactga tgtagctaat ttagtattta
   254341 acttacttgt tgcataataa tctaggaaaa ataatggttc ggccccttga acaattaagt
   254401 catttacgca catagcaact aaatcgatac caattgtatc gtgtttattt aacatttgtg
   254461 ctattttaag tttggtacca acgccatctg tgcttgaaat taggattgga tgtttgtatt
   254521 tgttaaaaga taattcaaac attgcaccaa agccaccaag accagctaac acttcaggcc
   254581 tagtggttga tttagcaatt ggtttgattt gttcaataag tgcattacct ttggtaatgt
   254641 taacgcctga gtcaaggtat gagagtgata acatgatagt tcttccgtat aattggtttt
   254701 cttaaatttt tttatagtaa ataaaaaatg agtttttctt cattacctaa tttgctttca
   254761 attttacgca ttattttaac agtgccagtt gttatgactt tattagatcg tcaatatttt
   254821 ttagcaatgg tattgttttt tgttgcaggt attactgatg cgctagatgg atggattgct
   254881 aaacgttatt cctttcaaac tagattaggt tctattttag atccgatagc ggataagtta
   254941 ttattggtta gtagttttat ggctttatat gtgattagat taataccatt atggttattg
   255001 gtattgattt ttttacgtga ttttatgatt atttcaggta cagttgggtg ttttattggc
   255061 tcaggtgcct ctaaaaatga tttattatca ccttcaaaac tttcaaaaat taatactgta
   255121 ttacaaatta ttttggtttt atttttggta atagtacaga tttatccagt tccggtacaa
   255181 tatagtacta ttttctttat tattatagcc acctcaacta tgcttagcgg tgcagattat
   255241 gcatggattt ggattgaaca aattattttg caagagaaga aaaatccgca atgaatcaac
   255301 ttggattgcc acttttattg aattcaaaaa tattattatc taattttatt ggtaataaaa
   255361 atcagcaagt tttagatttt gttaacaggt tgtttactca aaaaagatca gccgttgtct
   255421 ttatttcagg cactaaatct agtggtaaaa cgcacttatt acaaggttgt gcttttagcg
   255481 cgctagataa gaagttaaat gttgcttata ttgacataaa gcaagagttg ccaaaaggaa
   255541 taataagtga tttaacttct gttgactgga tttgtattga taatgttgat tgtttaagta
   255601 ttactcaaca acaagcttta tttgatttat ataatagaaa taagccaact agtgttaagt
   255661 taattattgc tgcaagcagt tcacctaatg aattgaactt gttaaaggat ttgaaaacac
   255721 gcttgtcttt agcggttgct tttacattgg aagtgcttaa tgatgaacaa aaaattctta
   255781 ttattgagcg taaaatggcg gataaaaata tcaatataaa tagcaaagtc tatcattatt
   255841 tgtttaaagt tttttcacgt gatttgaatg atattctgaa tgtaattagt gttttagaag
   255901 aagcttcatt gcaacaaaag agtaatattt ctattccttt tgtcaaacaa atattaggta
   255961 tttaagattt ttctctaaat ctgaattgtt caattttagg cattagtttt gaaaaattaa
   256021 tttttttgaa atctatatat ttttttttga taatttttac tagattagat atatctttga
   256081 tttgattgct attgtcaatg ttaagttttt cttgcaaagc aagcaaacca cccattttaa
   256141 tctttaattg ttgtctgatt aataaattat tttgatggtg tatatttaag acaaaattgc
   256201 tattatcacg caaattagta tataacaatt gacattggtt ggaatatgag tgatccaaac
   256261 aaacaccaaa ctctttttct gctatacaat cctttgtact aaatttacaa ccacatctac
   256321 cgctaattat tagcttgtca aaagggcagg tatagtgttt gtttgacata atgataaacg
   256381 ttttgtgttt atatggataa ttaaaacatt ataatacaag cttttatttt atttgtgcta
   256441 attcattagt agcgctaaac attacatgaa ttatctacct atttttattg atattaagca
   256501 aaaaccttgt ttagttgttg gtggtggttc tattgcttat cgtaaaatca atcttttgtt
   256561 aaaagcttat ggtcaggtaa cttgtattgc aaaaagtagt tgtaaaaatg tagctaaatt
   256621 agttaataac aaaaaaatta tttacattga aagaagtttt gagtcgtctg atgttaatgg
   256681 acaagttttg attatttcgg ctacaaataa cgcgactctt aataagaaag tatctgagct
   256741 ggctagtcaa aataatattc ctgtaaatgt aattgattcc ccggatttat gtacgtttat
   256801 tatgccttca attgtggata gatctcctat tttgattgct atttcatcag caggaaaagc
   256861 tccagtatta gcgcgtataa ttcgcgcaaa gttagaaagt acactgccac atgcgtatgg
   256921 taagttagca gaattagcag gtaattttag agaccaagtt aaggcaaagt ttagcagaat
   256981 tgaagataaa agatactttt gggaagaaat cttttctggt attattgctg agaaagtatt
   257041 ttcaggaaaa attcaggaag ccaaagcaga tttgcaggca caacttaata atactgttga
   257101 agctcaagta ggtgcagttt atttagtagg tggtgggcct ggtgatcctg atttattaac
   257161 ttttagggct ttacgtctta tgcaacaggc agacgtagtt ttatatgacc gattagtttc
   257221 agatagagta atggagttgg ttagacgtga tgcacaattg atttatgttg gtaaagaatg
   257281 tgataatcat gctgttccac aaggtgatat taatcaattg ttggtagatt tagctaaaga
   257341 aggtagaaga gtctgtcgtc ttaaaggagg agatcctttt atctttggtc gtggtggtga
   257401 ggagattgaa acgttggctg aaaatggtat accatttcaa gtagtacctg gtattacagc
   257461 agcttctggt tgttctactt attcaggtat tccattaaca catagagatt attcacaatc
   257521 ttgccgtttt gtgacaggac atttaaaaga tggtagtatg aatttgcctt ggcatgagtt
   257581 agcgattgaa caacaaacca ttgtatttta tatggcgctt aatagtgtag agtatttatc
   257641 aggacagtta atcatacata atatgcgtcc agatatgcca gtggcattag ttgaaaaagg
   257701 gacgacacct gagcaaaagg tttacataac aactttaaaa gaattaccaa atttagtaga
   257761 aaatgaaacc atccacgccc ccactttaat tattattgga gaggtagtga aattaagaga
   257821 aaaattaaac tggttcgatg ctaaacccat atcatctaaa aaataacaaa aattgtaagc
   257881 cttttttgtc tagaagtatg gttatttagc accaagtttt tttgcaatga ttgccgctgg
   257941 acaaaatcct gtaaatgctg attgaaacag attaaaacca acaaatactg ttaaccataa
   258001 ccaattggaa ttataagcaa atggacttat ttcttgtgca cctaatagta atgagataat
   258061 aataacgaca ccagctactg ctgatacaac attattgatt gtcatacatc tttcctccat
   258121 attttatttt ttgttattat aacattaatt ataggtataa tttcgaacct ttaaactctc
   258181 ttgaatagta ttagatttaa atgcgggagt ggtggaattg gtagacacgc tggatttagg
   258241 ttccagtgtt gaaagacatg agagttcgag tctctccttc cgtaccaata ttaggttatt
   258301 aatttgagca tgacaattat tattcaacat agtttagatg aaaatattgc taagaaaatt
   258361 tcaagcaaat tccaagtttt taatactcat atccgtcata aaatagtatc agctaatctt
   258421 gatgatttaa gacaacaata tcaaattgat tttaactatt tgcctaagct tgacctttct
   258481 agtattcaat tgtttgttag cgatatggac tccaccctga ttaatattga atgtattgat
   258541 gaaattgctg attttgctaa tattaagcga gaggtaggcg ttattactga acttactatg
   258601 caaggtaaat tggattttgg tagttcttta tttaagcgtg tctccttgtt aaaaggactc
   258661 agtgttgatg tgttagataa ggtttatact cagcgtttat cagtcagtcc tggtggtaga
   258721 tctcttattt cattttttaa aactaagttt attaaaaccg ctattgtatc aggtggtttt
   258781 acttatttta ctaatcgttt ggttaaagat ttagcgctag attatgcatg tgctaatgta
   258841 ttatcaattg aaaataatca attaactggt gttacagagg gattgatgat taatgcacag
   258901 gctaagtcag attttgttaa agcgttgtgc gataaacaag gttggtcata tagtcaggtt
   258961 attgtagtgg gcgatggtgt taacgattta gatatgatga atattgctgg tttaagcgtt
   259021 gcttatcatg ctaagcctag tgtcataaag catgttgata ttatcattaa ctttggcggt
   259081 ttagataaaa taatagattt attcaatcaa taatctttta tgttaattga aattggacat
   259141 tttgcattgg tacttgcgtt ggtgtttgca atgttacaag tgattttacc aactataggt
   259201 atgattaagt acgatgttgt actttctagc ttatctagac ccttgttatg gatgcaattc
   259261 ttttggatac tgattgcttt tgttattctt gttaatgctt ttgttgtgga tgatttctct
   259321 gttagatacg tagcaagtaa ttcaaatact caattgccca atatttttaa aatgtcagct
   259381 atttggggtg cacatgaggg gtctttgtta ttatgggctt tgattttagc cgcttggagt
   259441 gtagcagtat ctttattttc tagacgttta cctgttgaag tattaaacca tattttaatt
   259501 attcttggtt taattagtat tgggtttttg ttgtttttgt tattaacttc taatcctttt
   259561 gagcgtttag atattgtgcc attacaaggc cgagaactta accctttgtt acaagatttt
   259621 ggtttaatta ttcatccccc tatgttgtat atgggttatg tgggaatggc tatccctttt
   259681 gcttttgttg tatcatcact gattcgtgga cagttagatt ctacttggct taggtggtca
   259741 cgcccttgga cgttaatagc atgggcattt ttaacgcttg gaatcacact tggttcttgg
   259801 tgggcgtatt atgaacttgg ttggggtggt tggtggttct gggatccagt agaaaatgct
   259861 tcatttatgc catggttagt ggcaacagca ttggttcatt ctttaagtgt gagtgaaaag
   259921 cgcagtgcat ttaaacactg gactgttcta ttggctattt ctagtttttc gttaagttta
   259981 ttaggtactt ttttagttag atcaggtatc cttacttcag tgcattcatt tgctactgac
   260041 cctgataggg gtttatttgt tttgatattt ttagtgattg tgattggtgg ctcgttagta
   260101 ttatatgctt ggcgtgctac tttactcatg caaagtagta ataccttttc tcttttatca
   260161 agagagagcg gtttactagt taacaatata ttattagtag cttcaatgtt aagtgttttt
   260221 ttaggcacat tctatccact actattggat gcattaggtt tgggtaaaat ttcagtaggc
   260281 gcaccttatt ttggttcagt gtttgtacct attatgattt tggcaatatt gattatggcg
   260341 attatcccct ttttacgttg gaaggaagat actacacaaa gagtggttga cttactaaag
   260401 cgggtttgga taggtgtagg tttgttgttt gtgattagtg tatttttgat cgataatatt
   260461 ttagttttgc tagccgtttt tttatttatt tggatagttt cacattcatt agtacttttg
   260521 tttcaaaggt taggacaaaa aggcagtata aatcttgctt tcattggcat gatctttgct
   260581 catattggta ttgccgtatt cttattaggt gctacagtta caacccaata cggcgttgaa
   260641 aaagatatac aaatggaaat tgacaaacca ataactataa aaggttatga ctttattttt
   260701 aaaggtgtga cacgtttatt tggtccaaat tatcaaggaa ataaaggtca tgtagaggtt
   260761 tattttgagg atgaaaaaat agcagatttg agacctgaaa aacgccaata cactacaggt
   260821 atgccaatga ctgaagcgag tattgattca tcattatatc gtgatattta tattgcatta
   260881 ggtgaatcct tagaagatga ttcatggagt ttaagaattt attataaacc tcttgtgcgc
   260941 tggatttggt tgggaggttt attgatttca ttaggtgcgt tactaagtgc atttgacaga
   261001 agatatcgat tgagaataaa agaatgagtt tatacctatg gtttgcttta atggtgattg
   261061 tttcttttat ttggataatc tggtttttgt atcgaccgat taaatctaat aaatttaatc
   261121 tagaaagttc taatatttcc ttaggcaaac aaaaattatt agaacttgag caagatttac
   261181 atcaaaattt gattgataaa aagcaattca atcaggctaa agaagagatt tcaataacat
   261241 tagctattga actaaaacaa gcgaatagta ttaatactag tactaataat aacatattaa
   261301 taatagtatt aatactagta ttgttacctg tcatgtccat tggtttttat caatatctga
   261361 cttcaaaaaa taacatgaac caatcatctt caaatacaga agagtcatta agtttagaac
   261421 aaagtgttaa taaaattgta cagtatttac aaactaatag agatgacgct gaggcttgga
   261481 gaatgcttgg acttacgtat tttgaattag gagaattaga cttatcaatc aatgcttatg
   261541 agaaatcttt tcaaattaat cctaaagatc caagattatt agttgaatat gcatctataa
   261601 tgatcagtgc taatggtcat caattttcaa atcattctat taaattaatc aaacaagcct
   261661 tggagattga tccaaatgca tcagattcac tgtatttagc gggtatgttt gctgcaaggc
   261721 aaggagattt tgatttagct aaaggactat ggcaacgtgc acttaatgct ttaccaaaag
   261781 acagtattaa cagagtagct ttagttaata ttttatctga gttaaaagta cttgaatcaa
   261841 gtagggatat gtctaaacat tttattagtg tacgtgttaa tgtgtctgat gaaatactaa
   261901 agtttagatc tagtgaagat tttataatga tttatgttaa agcagctaag ggtagagcta
   261961 tgccaattgc gattaaaaaa atcaagttaa aagtttttac aggccaagta gttttaaccg
   262021 accaagattc cgtgatacaa gacaatcaat tatcagccta tgatcaagta attgtggtag
   262081 tacgtattag tgcaactggc tctgctataa gaagtataga cgatatacaa gtgctaagta
   262141 aagtcattaa tgttgctgat aatccatctg tttatttgaa tatgaaataa tttaatgagt
   262201 aaaactttaa cattagcaaa aaagctagtt agtatagatt ctattacccc gcaagataaa
   262261 ggctgtcagt ccattatgat tagtcattta aatgatctta attttgaaat tactgattta
   262321 aaatttggcg aggttgataa tttttgggca attcgtggcc agcaatctcc tgtgtttgta
   262381 tttgcaggac atactgatgt tgtacctgtg ggcaatgaat cagaatggca tatgccacct
   262441 ttttctgctc aagttaaaaa tggtatgttg tatggtcgtg gaacatctga tatgaaaggc
   262501 tctttggcag ccatgcttag tgcaactgat agatttgtta aagatcattc taatcataaa
   262561 ggctcaattg gttatttaat tacttctgat gaagaaggtc ctgctattaa tggtactgtt
   262621 aaagttgccc aatatttaaa aaaaataaac caaacggttg attattgttt agtgggtgag
   262681 ccatcagcca ctcatgagtt aggagatatt attaaaaatg gccgtcgtgg ctctttaaat
   262741 ggttctttta aaattattgg aaagcaaggg catattgcct atccgcattt ggcaagtaat
   262801 cctattcatt tagtcatacc agcattaaat gatttgtgta atgaagtttg ggatgagggt
   262861 aatgagtatt ttccagctac tagttttcaa atttctaata tccagtcagg aacaggggta
   262921 actaatgtta ttccaggtga aagtaatatt gtttttaatt ttcgttattc cacacaatgc
   262981 actcaagaac aattacaaag tcgagtttgt gcaattctag ataaacgtaa ttttgaatat
   263041 caaatcactt gggaacattc tggttatccg tttttaaccc caaagggtaa attggttaat
   263101 gcttgtgtta atgctattaa aacggtaaaa aatataaata cccaattatc cacttctggt
   263161 ggtacttcag atggacgctt tattgcccca attttaaaga ctagagttat agaattaggt
   263221 ccttcaaatg caactattca tcaagttaat gagtgtgtat ccatccaaga tttagaagat
   263281 ttaagtgata tttattatca tattctaaaa aatatactga cctagctcat gcgttttgat
   263341 attattactt tatttcctaa catgtttaat atcattaagg atgaaggtgt tgtcgcgcga
   263401 gctatcaaaa aatcacacct ctcagttcat atttggcaac ttagagattt tagcaataac
   263461 aaatacaaaa atattgacga taagccttat ggtggtggtg gaggtatggt aatgcaagtc
   263521 aagcccattc gtgattgtat taacaaaatc aaacaatcaa gtccaaaaac taagatcatt
   263581 tatctatcac cacaaggtca gccacttaaa cataagctaa ctaaagaatt gtccatgttt
   263641 gatgcaatta ctttattatg tggacgttat gaaggtgtgg atgagcgcat tattaatcac
   263701 gatattgata tggaaatatc tattggtgat tatattatta gtgggggcga attagcagct
   263761 atggttctta ttgatacggt tagtcggcaa atcccaaatg tacttggtaa tattaattca
   263821 ttaaatgatt cctttacaaa taatttgtta gattacccaa attacacgcg tcctaaaatt
   263881 attgacaacc aaaaagttcc tgaagtatta ctaagtggac atcaagctaa tattaatatt
   263941 tggagaatag agcaatccat taaaaaaact aaaaaaaaac gtaaggacct tttaaaaaat
   264001 taggtacatt tgtattagat atcattagtt ttattttatt agaaacaata agatggttat
   264061 agaactaagt cattagatac tatagattgt tgtttatttg ctaaataatt tttataatct
   264121 gacgatataa tgcaatttaa ttacgataaa aaggagggaa atatgaagtt tgtgacagca
   264181 attctaagac cgcataaatt agacagcgtt agagaggcgt tatctgaagt gggcgtatct
   264241 ggcgtaacag tgactgaagt aaaaggtttt ggtcgtcaaa aaggacatac tgaattatat
   264301 agaggaacag agtatcaaat tgattttttg cctaaaatta aattagaaat tgcaattgag
   264361 gctaaaaaac ttgatgaagt gattgaaatg attagtagtg tgacgaattc tggcaaggta
   264421 ggtgatggaa aaatttttgt ttctaattta gataaagtgg ttcgtattcg tacgggcgag
   264481 acagataaaa atgcacttta aggagttagt agtgaagaaa ttattagtaa cattggcata
   264541 cttaccaatg agtgtgtttt cacaggatat taacggtgct gatacagctt ggataatgac
   264601 atcaacagcc ttggtgttat tgatgacatt gccaggtttg gcattatttt atggtggttt
   264661 agttcgtact aaaaatattt tatcagtact tatgcaatgt tttactattg caggtattgt
   264721 gagtattttg tggtttgtgg taggatattc gattgctttt tcaggggata gtccttactt
   264781 tggtgatttt tctaatatac ttttaatgaa agttagtata aacatgatta ataactcaat
   264841 tccagaatct ttatttgtga tgtttcaaat gacatttgcc attattacgc ctgctttgat
   264901 tattggaggt tatgcagaaa gaatgaaatt ttcagctgta ttgctgttta gttctatttg
   264961 gcttttagta gtttatgcac ctattacgca ttgggtgtgg ggtgggggtt ggttaggtaa
   265021 tatgcttgat tatgccgggg gtacggttgt tcatattact gcgggtattg ctgcactagt
   265081 agctgccatt gttttaggac ctagaaaagg ttttttaaaa agacctatac caccacataa
   265141 tatgactatg actattacag gtgcagcaat gctttgggtt ggttggtttg gatttaatgg
   265201 tggctctgct ttagcagtag gagggaatgc agctatggct attttagtaa cacatatctc
   265261 agcagcaaca ggggcgatta cgtggatgtt ttacgaatgg attaagtttg gtaggccaac
   265321 tgcattaggt acggtaacag gtatggttgc aggtttggga acaatcactc cggcctctgg
   265381 ttttgtaggc ccagtaggtg ctttagtgat tggttttatt gctggtattg tgtgttttaa
   265441 tgcggtgatt atcatcaaac aaaaatttaa aattgatgat tcgttagatg tatttccagt
   265501 acatggagta ggtggtatta tgggcacttt aatggtagga ttttttgctt ctaaagaatt
   265561 gggtattttt tctggacaag gtggttggga tcatgaagca attttgattt atgagcaatt
   265621 acaaatacaa tttataggtg tggtagcaac tgttatttat acggctattg ctacttatct
   265681 tattcttaaa atagtgaatg ttataacagg cttgagagta agtgaggagg aagaacaaca
   265741 aggcttagat attatttctc atgaagaaaa aggatacgat ttgtaagtta agtttggttt
   265801 aattaaactt gttaattgtt gaatcattag taggttttta tgttgataaa aatggattcg
   265861 tatataattc acactaatta gttttattaa atagttgaag tgcatataaa tcacccacta
   265921 actggttcaa tggtcgcctt aattaccccg atgtttgatg atggatcgat agattttagc
   265981 gcactaaaat cattggtagc atttcatatt gatgctggta ctaaggcgat tgtttcaatg
   266041 gggactacag gagaaagtgc aactcttaat caggatgagc atattgaggt gatacgagca
   266101 acggttgaat ttgcaaactc atgtattcca gtaattgctg gtacgggtgc aaattctact
   266161 tctgaagcta ttaagcttac taaagtggct aaagaaattg gtgctgatgc ttgtcttcta
   266221 gttactccgt attacaataa gccgactcaa gaggggttgt atcaacatta taagttgatt
   266281 gctgagacgg tagatattta tcaaatttta tataatgttc ctagtagaac agcagtcgat
   266341 ctttctgtag aaacagtaat tcgcttatcc gatattaata atatcattgg tattaaagat
   266401 gcaacgggta atttgaacat tgcacaatca ttaattgagc aatgttcgga tgactttttg
   266461 ctttatagtg gtgatgatgc aacagcagtt gaatttattt tgatgggtgg gcatggcggt
   266521 atttctgtaa ctgctaatgt tgcaccaaag caggtggctt ttgcttatca atttgcactt
   266581 gagaataaaa gagaattagc agaattaact aacgaatcac taattgattt acatcaacat
   266641 ttattttctg aatctaaccc aatacctgtt aaatgggcaa tgtataaaat gggaaaatgt
   266701 aataatggta ttcgtttgcc tttaatgacg ttatcaaaac aagctaaaat gatattagaa
   266761 caagatttat ctaatttagg gattatataa taatggtaat taggggatta atagcattat
   266821 ttttggtatt ttctttgggt ggttgccttt ctctcggcaa taaagaaggg caaaaacata
   266881 atggaatagg tggaagagat gttgaatatt attcaaagaa aatattaact tctttagaga
   266941 ttccgccaga tttaaccaaa cctagtgtta aaaattctct aaagttaggt aaatatgttt
   267001 ctaattttca agaagatttg gttaattttt ctaaacaaga tagttcaatt aaaaaggttt
   267061 caaatatttt aagaacccct actaatgttg aggtaattaa gtctagtagt tttcgctggt
   267121 tggtggttga taaagaacca gatgtagtat gggaattagc taaaagtttt tttcaatttt
   267181 atggctttgt tattaagaag gctagtaaaa agactggaat tatggagact aattttttag
   267241 aaaatcatcc agaaatttct aatcaatctt tgggatttat tcgttctatg tttagaaaag
   267301 taacaaaaat gaaatacaca ttaccagttg ctgataaata tcgacttcgt attgagccga
   267361 ttgatgataa taaatctgca gtttatctat cattaagttc aatgcaagaa gtgctgacta
   267421 ataaaggagg tgatgatgaa aatactattt ggcaggctca atctaaagat ccaatattgg
   267481 aaacagaaat gctttatcga ttaatgattt ttttaggtag tgatcatgtg cttgctaaag
   267541 aaaaaattct tgctgctaga gagcaacaaa tattaactgt tgtagttgct aaaggcgttg
   267601 gtggttatgc taagttggtt tttccattaa cccaatatga aacttggagt aatataagtt
   267661 gggctttaga tcaaattggg gctgatattg aagataaaga tattagagag ggtagttttt
   267721 atattaattt tgctaaagaa gaagatgaaa gtatattttc acgattgttt agtaatagtg
   267781 taataaaaga atcttttcaa attgttgtta gacaagttga tagtaatata acagaagtat
   267841 attttaatga tttatctgaa gaaaacaaac aaacaacaat tgactttagt tatcaatttt
   267901 taggcgatat tgccaaacag ttctagttaa ataaaagctg atgctatcac aaaatattat
   267961 tgataagatt attcgacaag atatattggt agatgagttg ttagatgaag aattatctat
   268021 attttgtcaa acagctaacc tagcttatcg gtctggaaag cctattatta gtaacgaaga
   268081 ttatgatttt atttatcttg ctacgcttaa aaataaagaa cctaacaatc cgttattcaa
   268141 atctatagag ccagaaggac gagcttttgc tgaggaaaaa gttttattgc cagagttaat
   268201 gctttctatt gataaagcat attcatggaa tgaaatgagt aaatggatag aacgattaga
   268261 aaaatcaggc atgctgattg gattggattt gaatgctatt caaattaaag ccactcctaa
   268321 attggatggt tttgctggat ttgatgatgg caatcgactt tatacacgtg gtgatggtaa
   268381 aaaaggcagt gatatctccc gagtattcaa gcgaggattg tgtgttttta aggattctgg
   268441 gcgcggactt ggtgctggcg aaattgtggt taagaaaagt tattttgaaa aatatttagt
   268501 gcatagtttt gaatatccac gtaactttca atctagtctt attaaagaaa aagctttaga
   268561 tgaacaagct caaaaggcta ttatcgacaa aggagcttta tttgttccgt ttattaagtt
   268621 gcctatttgg tcaggttcta tgactgaatt agttgctaaa tttgaagaaa ttgtttctca
   268681 agtattggta atggtagatt tcgatgtaga cggtgtggtt tttgaagtga ttaatattga
   268741 tttaaagacc caaatgggcg ctaatcgaaa atttcatcgc tggcaaattg cttttaagga
   268801 aaacaaagat attgtacaag ttaaggtgct taatgtgatg cctcaagtgg gacgtagtgg
   268861 aaaaataact ccagttgcag aggtagaacc tactttatta agcggtgcaa ccattgtgcg
   268921 tgtaacaggt catcattatg ggttggttaa agaacaaggt ttgggtatag gtagtgtggt
   268981 tgagttaaca cgttctgggc tggttattcc taaaattata tctgtgttaa agccaatgcc
   269041 tgttgatatt cctgataatt gtctaagttg tggtatgccg cttgtttggg agtcagattt
   269101 tttagtatgt gttaatcata aaaattgtcc tgctcaaatc attggaagaa ttacctattt
   269161 ttttaaagta ttagctaata atgacggttt tggtattgct actgttgaaa aattatatgc
   269221 acataatatt aggtcagttt cacaaattta tactttaaat gtagagcgtt taatggcaat
   269281 aggctttggt gaaaaaacaa gtataaacct tattagtcag ctaagtcgtt ctattagcga
   269341 aaaaattgaa gactggcgtt ttttagcagc atttggtatg catcgaatgg gcttaggtaa
   269401 ttgtgaaaat cttttaaagt cctatcggtt gaatgatatt tttgatttaa ctttagagca
   269461 aataaccaat atagatggtt ttgctgaatt aacagcacag gttattgtac aaggattagt
   269521 ttctattgtt gacgaatata atcaaatata tcagtataac tttaatttag atacaactgt
   269581 atttactaaa gatttacaaa cattaatgca tgaattattt gataaaagaa ttgtattcac
   269641 tggtaaaatg aattgtccaa gaaatgaaat gaaaaagcat gctaaattag ttggtattaa
   269701 agtttcaact actattagca ccaaaataga ttatttggtt attggaagta gagttgggca
   269761 aaagaaaata caaaatgctg aaaaattagg tgtagtagtg atgactgaag ctgattattt
   269821 atctaaaata accatgtaac aatgagtacg aatagttctt atgatatgat tttattattt
   269881 ttaataaaga aattttcctt tatggttata atcgttgtag ttaatgttca aaggtgggcg
   269941 gtttagtaaa gggtataagc gtttatttag atttattgta aaatgaattt tagatagacg
   270001 tctttttttg tcattttaat tatgtagctg aaagagattg aggtcaatca ttaagtttgt
   270061 attttttata agcataacga ctaggttttt ttcgttttta aaaaaaggag aaattaaatg
   270121 aaaatggtaa cagcaattat taagccgttt aaacttgaga atgttagaga agcactttct
   270181 gaaattggta tttcaggtat cacagctaca gaagtaaaag gatttggtcg tcagaaagga
   270241 catacggaac tttaccgtgg tgcagaatat actgtagatt ttttacccaa agttaaacta
   270301 gaaattgcta ttgtagcaga tcaagtggat aatgtagtta aggttattag taccgctgct
   270361 aaatcaggag atgagggcaa gattggtgat ggaaaaatat ttgtttcatc attagagcaa
   270421 gtacttcgta ttcgtactgg tgaaactggt tcaatagcat tataagaagg gagcattgaa
   270481 attatataaa taaatgtaat ttatttatat agatatctaa tgattttttg atattataaa
   270541 tattcttcta tttgcaagaa tttgcatgat tatagcaggt gttttactag aagacattag
   270601 tagttcaaat aataaatatt cgaattttta ttttcaggtt tttatggttt ttggtaaata
   270661 ttactaatca gtaataacat gtatttgagt atttgaaatg aagttaatac ttaaatgagt
   270721 gatggatatt cgagtttttg aagagtaaaa tcttttatat gttaatgttt aagaatttgg
   270781 tttatagtta cattctttat gttttacaaa ataaaggtaa caaataatgt aaagaaaata
   270841 atcaatttta gtttttattt tattgaatta gaacaaggaa agatatgaaa aaaaatataa
   270901 taatattatt attatgctta atttcaatat ttaattcagt gtctttagct gaagctaaaa
   270961 ttcaatcagc agttagtgct aatattacta tcgctaatga ttatgtttgg cgtggtaaaa
   271021 ctcaaaccaa tgataagaaa gttgttcaga ttggccttga ttataatgtt ggcaacggtg
   271081 cagtattagg tatttggagt tctaatgttt taaacgggac tgagtttgat tactatattt
   271141 cttattcagg tgaggtagga gatattgatt atgaagttgg ttatattgct tatcgttatt
   271201 cagaagatgc tattgttaat cgtttgaact tcgatgaagt ttatattggc gggtcttata
   271261 gtgatttggg cttcacttat tatataggta atggtaaaaa aatgcttaaa gtaggtaatt
   271321 atgttgaagc tagttataat aatagtatta atgatataga tgtttcattg actgttggca
   271381 gatattttga agcagttaca ggtgatagta atgattataa tgtatatgga attagccttg
   271441 aaagatctta taaaggattg gaccttacat taaggtttgt taagaataat tctcataata
   271501 tctttaacga gaaaaataca gtatttagta tcagtaaatc attttaaatt ccattttttc
   271561 tctaaaaaat accaatttta gttatgattg ggtattttta acggtagaat acaatctttt
   271621 tgattaagga taattgctat gcaagttcaa gagattatgt caacaaacgt aaaaacagtt
   271681 actcctgatc agctagttaa agacattgct attatcatgg taatggatca tattagtgga
   271741 gcaccggtag tagatgttaa taatacttta gttggtatta tttctgaaaa agatatctta
   271801 caacatatgt ttccaaaact agatgaggtg atgagtgata cgtactttga tttcgaaaat
   271861 atggagcata attataaaga cacaatgaat gttagagtgg gtgaattaat gactaaagag
   271921 gttgctagta ttgatttaaa tatgccttgt cttaaggctg catcaaccat gtggcttaaa
   271981 aattttagaa gaatccctat aactcataat aataaattag ttggaattgt tagtattggt
   272041 gatgtgcata gggctatttt taaatcacgt attaagtgaa tattgcttta aaaattatct
   272101 tagttgataa aaatacgggg cgttcagcta tgttgcgtag agctttacaa gacaagggtc
   272161 acgaagtgat ttgtcgtatg cgtgatagtt caaatttaca agatagtaat gaaatgacgc
   272221 atgcagatgt gttaattgtt aatgcagata ttcctgatga gcaagtattt gcaaatttga
   272281 tagatattaa taaaacaaaa cctaagccta tcgtgatgtt tactaaagaa tcaaactctg
   272341 agatggctaa ttctgctatc aaatctggtg tacatgctta tattgttgat ggacttgaag
   272401 agaatagggt gcagcccatt attgatgtag cgattgctag atttagagag tttcaagcac
   272461 ttaaagacga gttagatgct actcgtaatc agctttcaga gagaaagaaa gttgagaaag
   272521 ctaaaggctt gttaatgcaa cataataagg atattaatga agatgaagct tatcaatcgt
   272581 tacgtaaaat ggctatgaat aaaaataagc gtattgttga tgtggctgaa agtgtgatta
   272641 atgcttttga attgttagag taaagttata ttaattttta tttagttttc tattttattt
   272701 ttattccaat cgtcattatc tgatactttt ttttctttcg aattggtttt gttagaattt
   272761 ttaggatagt tgttagatat ttcttgttta ttttgtttaa ataaagggga aaaaataaga
   272821 cctgcttcaa ataataacca aattggaatg gcaattaaag tttgagagat gatatcaggt
   272881 ggtgttaaca acatgcctag aataaaagca ccaataatga tataaggacg gttgtttttt
   272941 aatttttcaa ctgttgttat cccaaatata ataagaagaa ttgtagcaat tggtacttca
   273001 aaggctacac caaaggcaaa agaaactttg agaacaaagt ctagatagta ttgaatatct
   273061 ggggtaaagt cgacaatatt gggtcctata ctagatagga aaccaaatat aacaggaaaa
   273121 acaatataaa aagaaaataa caatcctgca taaaacaaaa tagttgttga gacaaccaat
   273181 ggtaaaatca tttgtttttc gtgtttgtaa agtgcaggtg caataaatga ccatattttg
   273241 tataaaagat agggcatagc tacataaaca gatataataa gagacatttt taagggtgtt
   273301 aaaaatggtg atataatacc gatagcaata atattagtat cttgaggtaa aacgttaata
   273361 atcggtgctg caataaaact ataaacctca ttagcaaatg gaaagatact cataaaaata
   273421 attagaatga caataactga gtgtaataga attttgcgaa gttcaactaa atgctgaaca
   273481 aaagtcattt ctttattgat cattattttt gatcaatgtt atttttaatg tcatttaaag
   273541 tattctttgt ttcatcaata acttctaaaa tattagattt tttatccata gagtttaagt
   273601 gtttttttag tttttctatt tcaagttcat cactgatatc atcttgaata ttgataataa
   273661 aacgctttac tttgccaata taagtaccta cttctttaac aatttcaggc atgcgttttg
   273721 gaccaactat aattaatgta ataataccaa ttaaggaaaa ttcccaaaag ccaacatcaa
   273781 acatgtttta tttttcttgt tttatttctt ttttaataat tttagcttca acaatatcgt
   273841 ctttattatt aatactatct gttgattcct tcatggcttt tttaaagcct ttaatggcat
   273901 tgcctaaatc accaccaata tcttttaatc gttttccacc aaaaagaagt agcacgatta
   273961 ctaaaataat aatcaattca aatggtcctg gcatcatagt ttttctccta ttgttcagtt
   274021 gttcctattg gctttttctt tcaaaccaga caagccaaat cgtctggata attcatttgt
   274081 tatttgctct acttttattt ttttaaaacg taataatact aaggtatgaa accaaagatc
   274141 agctatttcg taaatgattt tatcatttga accatcttta gttgccataa ttacctcagc
   274201 agattcttca gaaatttttt ttaaaatttc atctgttcct ttattatata aagatgaaac
   274261 ataagattta tctgctttag cagactttct ttgctctaaa atttgctcta attttattag
   274321 gatttcatcc ataaatatct cttggatttt ttatcatatt agtgatgatt ttccaatttt
   274381 ttttatccag ttgttgaaaa aaacatgata ttctacctgt atggcaagaa atacctccaa
   274441 tttgttcaat tttgagtaga ataacgtcat tatcacaatc tgtaaaaatt tctttaatat
   274501 gttgtatgtg tccagactct tcgcctttga accaaatttt ttgacgtgat ctagaataat
   274561 aaactgcctg ttgtttctta atagttagct ttagagactc ttgattcatc caagcaaaca
   274621 ttaaaatttc tcctgtttta aaatcttgag aaatggcagg tattaaacct ttttcgtcaa
   274681 attttatttg ctttaatgca ctcatttttt gaggatctca agtattatcc tatttaattt
   274741 tactgttaga tgatagactt tgtgtaagat aatttatttt aaatatttat taagtattga
   274801 tgaagtttca aatttagata attttttatc atcgcatggt tactaattct tctgcgctag
   274861 taggatgaat tgcgattgta tcatcaaatt gagctttagt tgcacccatc ttaatagcta
   274921 ctgcaaatcc ttgtagcatt tcatcaatac catgacccat tagatgacaa ccaataattt
   274981 tctcatcatc acccatacaa actaatttta aaactgttgt ggttttatga ttaagtaggg
   275041 catcagccat tggagtgaat tctgatttat aaatttttac tttgttaaat tttttattag
   275101 cttgtgtttc agttaagcca attgtaccaa taggtggatg tgagaatact actgtggcaa
   275161 tattattata gtctagatgt ctattgacca tattgttgta aagtctgtca gatagccttc
   275221 taccagctgc gattgctacg ggcgtaagtg gtgtttgagg tgtagcatca ccaagtgcaa
   275281 agatattatc aatattggta gcttgaaatt tatctgttgg aataaagcct ttttggtcgt
   275341 attttacacc tacattgtcc agacctaaat attttgttat tggatttcta ccaactgccc
   275401 aaataatagt atcaaatcca gaaaattcac ctttattggt aagaatggtt ttatcttttg
   275461 aaattttttt aatttgagta ttatgatgaa tagtgatacc atggttcaaa taatctttat
   275521 taagtgcatc ttgaatcatg tagtcaaaac cgcgtaataa tttatttgct ctactaaaaa
   275581 tagccacttt gctacctagt gaatttagca tgccagctag ttcaatgcca atataaccac
   275641 taccgattac agctactttc tttggtaatt cttctagtgt aaaaaaacca tcagaagtaa
   275701 ttccatattt agcaccttta atatgcggta cagatggctc tccgccaggg gaaagtacga
   275761 tatgatgagc tgtgtattgt ttgtcattaa cagatactgt gtttttgtta actaattttc
   275821 caaatccttg aatataatca attcctagtt tttctaaatg ctctttatac caattggtga
   275881 tacttttgat gtaattatct cgttttgtct tgagtttttt ccaagaaaat cctttctgtt
   275941 caacatcaaa gccaaaacct ttggaatttt taatgattgt tccagtattt gcagcaaacc
   276001 acatgatttt tttaggcacg caacctgtgt taacacaggt accaccaatc gtttttactt
   276061 caataactag gcattttttt ccatattctg ctgcacgttc tatgacagat agaccgccac
   276121 tacctgcacc aatgacaatc atatcataat ctttattcat tattatcctt taagtagaga
   276181 ctacatttct ttattaaatt tttggagtgt aatagttttt gaataaacaa atagtattat
   276241 taattcttta tcaaaatccc taatttttct cctaattcac tctaagttta ttatatcatg
   276301 ttcctttatt ggtcattgtt gtgtgccaaa atgactgata attcattatc ttgatgtcga
   276361 ttatacctaa tccattgatc ttaattattc cacaaaatat ataattactt tgcacatagt
   276421 tttagtcttt tggcaataac tctaaagtta ttttaatttg tctactcgcc attagaatga
   276481 atagattatg ccgtatattg ataggttttt agttattttg ttagctagaa taatatatgc
   276541 actaaaattt agtttagaag gttattattt tagagaaaat ataaatatag tttgattagt
   276601 tagtatctgt tttttagaat tattcaggta tttattatta tgttaattat atgtcttagg
   276661 ttagattctc tgtaatggct gtggttattt attttgttat ttattaaacg atataaatta
   276721 tctatttatt aataatagtt ttatacattg gtttgtacta gaattattta ttcaggtatt
   276781 tgcttttact agtatagata atcttaactg tttatatagg ttttaaattg tctatattaa
   276841 tttaactatt ttagtaaaag attatttttt atgtttaaat tcaatttcca tttgttgatt
   276901 atattcttgt tattttttta tctttactct aaatggtttg ttaaaatatt tgttagttaa
   276961 ataatttaac aaaccattta gttatctttt ggtatcaaga gttattacta ataatatttt
   277021 tattttccct cttgtgaatt agataataaa attaacttca actgttatat tttctggtcc
   277081 ttttaaaaat acttgtttag tatttagatt aggtataaat ttttcataaa aattaatttt
   277141 taacttattg atatgtttga tgaaaattgg ataatcatct cttacgaaag caatatgatc
   277201 aagtaagtta ttgtaattgt tagtttttat tgagaattta gcctttttac taagaatatg
   277261 aataattgct tcttgcttgt tttctggtga atataaccaa taacctggaa agataaaata
   277321 tggtctaaaa cctttttcta gaccaataac ttctgtaaag aaaatagcaa cagtattaat
   277381 attattacat cttagggcaa tatggctaaa tcttatgttc atcttttttg ttacttattc
   277441 tttaataaaa acctatgtta ggatataaaa tatgtttttg ttaaatagat atataattaa
   277501 attatgttac agtgtagttt aatatattaa aggagactaa gtaggggtta acggttaatg
   277561 gaaaaaatta ttttcttgtt agaaaaataa ataaagttat aacctagatt ttaaactagc
   277621 tttcataaat tgatctaaat taccttctaa aatattttgt gtattggaag attcgatacc
   277681 agtacgtaaa tccttaactc ttgattgatc tagtatataa gagcgaattt gatgtcccca
   277741 acttatgtca gacttgctct gttctaaact ttgtttttca gtattgcgtt tttgcatttc
   277801 taacttatat agtttagatt gtaattgttt aatagcttgg tttttattag catgttgcga
   277861 gcgtccattt tgacattgta caacggtatt agtgggtaaa tgggtaatgc gtacagctga
   277921 ttcagtttta ttaacgtgct gcccacctgc accactggca cgataagtat caatacgtaa
   277981 atctgatggg ctgatatcga tatcaatatc actatctatt tcaggggaga caaatacgga
   278041 acaaaatgaa gtatgccgtt ttccgttagc attaaaaggg gattttctaa ctaagcggtg
   278101 gataccaatt tctgtgcgta accagccaaa tgcgtattca cctttaaagt gaatagttgc
   278161 ggatttaatc ccagcaactt cgcctgctga tacttccatg agtttaatct tgaagttgtg
   278221 tttttcaccc cagcgtaggt acatacgtaa caccatttct gcccaatctt gggcttctgt
   278281 tccgcctgat ccagattgaa tgtctaagta ggcagaattg gcatctaaat cgccactaaa
   278341 catacgttta aattcaagtt tttcgattga agattgggcg gtatctaaat cattaatgat
   278401 gccatttgcc gtttcagtat cattttctgt ttgagctaag tttagtagct cttgtgcatc
   278461 ttctaaaata gcattcacct gttcaaaggt ttggcaaatt gatattaatt ttgatttttc
   278521 tcgtcctaaa gattgtgctt gattagggtt ttcccagata tttggatctt ccatttctag
   278581 tagaatctct tctagacgat attgtttctt ttttagattt aaatgtatgg atagagtacc
   278641 tgaacatttc ttcaaatctt caattttttg ataggttggt gataactcca tggaaatatt
   278701 gttttaacag atataaaaaa tccttaaatt tggaagactt acatcctgaa gttattatta
   278761 tattatttcc taagttctag atgggaaatt aattttgaat aggcagtttt gttattacct
   278821 ctaaggtaag ttagtaattt tttgcgttga gaaactaaat gtagaagtcc tcttcttgaa
   278881 tggtgatctt ttttatgagt tttaaaatgt ttagttaggt gtctaatgcg agctgttaat
   278941 aaagcgactt gtacattggt tgaaccagta tcaccaattt tactctgata ttctttaata
   279001 atttcttgga tattaatcga cataataaat tttttcaaaa taaaaataaa gaagaattat
   279061 acactttttt aaaaaagtta ataaaaagat gactcattat ttggcttggt tttaaagcgc
   279121 ctgtgaatcc ataaatattg ttctggtgct tttaaaattt gttgttgtaa tatttgatta
   279181 gttaattgtg cattttgttg actattagtg ataggataat ttgtcaagat aggagaaaac
   279241 tctaatgtat aggttgtgta ttgacgagta aaggataaag gaataacaac cgtattatca
   279301 atacgtgcta gtttttctgt ggcttttatg gtagcggtct gtatattaaa aaaaggtgca
   279361 aatatgctga tcttaatgcc taaatcttgg tcatgtgtgt accaaatggg caagcctgat
   279421 tttaagactc gtattaaggt tttagtatct tttgctttaa tcatagtgct accatgttgg
   279481 gtgaatattt tttgcatttg attgtcaaat aaagcattat tttgtggacg gtaaacatct
   279541 gcaaaatcaa agttttgcag taatattcta ccagcaagca tcattgtcgt aaaatgtcct
   279601 actagtaaaa taatattttg ttttttatct agggcgtttt gtaaaatttc agcaccttta
   279661 atatgatagt attgcttgag ttttttatcg tttaaataaa agcaatttgc agtttcaaat
   279721 aagccaatac ccagtgcttc aaagtgttgt ttgactaatt tctttacttg atctttgttt
   279781 ttctcaggaa aacattttgt gagattaata aaagcaattt ttctaaatct acttagaagt
   279841 gaatatagat ttttacctat tattttacct attgttaact gggttttaag tggtaattta
   279901 gcgcttaatt tcattaagcc aattaaaatc caagttggta taaatttagg atgaaaaaat
   279961 tttgtctttg tcattaaaat atagctttaa attttgatta taaaaaatgc catttattaa
   280021 cgcagatttt aaagatgatc tacctaatcg tgtaaatatt gttgacataa ttaatcaacg
   280081 tgtgccactc aaaaaggcgg gtaaagatta caaagcatgt tgcccatttc atcatgaaaa
   280141 aactccatca tttattgtct cagctgagaa acaaatgtac aaatgttttg gttgtggaga
   280201 tggtaatggc gtgattaaat ttgttatgaa gtttgataat ctgggtttag ttgaggcggt
   280261 agagaccatt gctagcgaat caggtattag tgtagtgtat gataagaata tcaaaccgat
   280321 agatacaaga ttaactcgtt atttagattt aatgcaacga gttggccagt tttatattca
   280381 gcaattaaag caatctcttg caaaaaataa ggcggttggt tatgtcaaat atagaggtat
   280441 tagcagtcaa attgccaagc gttttgagtt gggttttgca ccacccaata gtaatttact
   280501 atttggattt aaacaagatt ctcaagatat tgctgattta aaagtgatgg gattgttatg
   280561 tgatgatcaa tatcgttcag gaaaatatta tgatcttttt aaagatcgta ttatgtttcc
   280621 tattcataat aataaaggta atattattgc ttttggtggt cggtcgtgta ataacaactt
   280681 taaggcaaaa tatttcaatt cacctgaaac gcctattttt tcaaaatcaa aagaacttta
   280741 tggtttgtat catatgcgta aatattcacg ttcaattgat tatattttag tagtagaggg
   280801 ttatatggat gtggtctctc ttcatcaagc gggcatatca caagtagttg ctactttagg
   280861 tacagtaact acggtagagc atttaaatat tctatttcgc acaacaaata ctattatttt
   280921 ttgttttgat ggtgataagg caggggagaa agctgcttgg cgagcattaa atattacttt
   280981 accagtgatt aaggcaggta taactattaa atttttattt ttgccagata aagaagatcc
   281041 agatacttta gttaaaaaag aatcaagcca agcgtttgta aaacgtattg agaatgcaca
   281101 atttttgagt aaatttttat ttagccatat taagacagaa gtagatttta acacgattga
   281161 aggaaaaacc ttatttttag aaagagtatc aatgttactt agaaaaataa attataaaac
   281221 ttaccaacat cagttgttag aaggtttggc aggtgaagtt aatcaaagta ttgaacaaat
   281281 tgaatctata ttagagcgac aagatatatc cactcaatct aatacattta gcatatcgaa
   281341 aaattatgaa gaaccaccta tgtttaattt ttatgatagt gatgaaaagt atcaagtacc
   281401 aatgtcagtt cccttaataa gtaataactc attaatagat caaatgattg gtttattgtt
   281461 aaattatcct tccatggttg ataaaacggt aatgttaagg gtgagaaaaa ttaataatgc
   281521 agatatattg caaaagttag ctaatttggt tttgttacaa gaagatatta ctttggagac
   281581 tatggtagaa caatttcccc agaaaaaaca acaattgctt aatttatata ataaaaaaag
   281641 agttttgaaa aattatgatt ataaggatga atttttggat gctttgctaa agattgagga
   281701 aagacaaaaa gagaaaagcg ctttattaat tacaaatgaa atagaatata caaaaaattt
   281761 acaagcaaga aaaggcaaac ctaaaagtta gttttttatg tttaatttga tttagtcgtc
   281821 attgattaaa atatattcta tttcctcttt aaataatata tttgggattt ttaacagtta
   281881 taaaaacact aaaaaatact taactaaacc ttgtctgtgc taataatttt gtacctatac
   281941 tagtattaat tttttttaaa atagtcgata ttttttctct cataataata gttctattta
   282001 ttttttatgt ggttgtattt tagtttttac ttgctactcg taaaattgca ctacgagcgc
   282061 gtttattatt gtcaatttct gctttgctgg taaggtattt gcctaaatcc tttagataag
   282121 ttttttcaat ttcattctca ataataggca aaccttttgg caaagttttt tgtcgtgaat
   282181 ttttttgaat aaaacgttta acaatacgat cttcaattga atgaaaacta ataatagata
   282241 gtctgccatt tttgcttaaa atgtctttgg attgttccaa tacgcttata agttgtttaa
   282301 gttcttggtt gataaaaata cgtatagctt ggaaagtacg tgtagcagga tgtttgtttt
   282361 tttgcttctt gaccacttta ctaacaatat tggcaagttc taaagtagtt tctaatacgt
   282421 gatttttctg gtattttttt attttattag caatatggcg tgattttttt tcattactaa
   282481 attgataaat aacattggca atttcttctt cattggctga ttttagccat tgagtagcac
   282541 tcattcccgt agtttggttc attcgcatat ctagcggacc atcaacccta aaactaaaac
   282601 cacgttgtgc gttttctaac tgaggggatg aaacgccaag atcaattaaa ataccgtcaa
   282661 tcctacctat taatccttgt ttagttataa tagatagcat tttggaaaat gcactgtgga
   282721 taagggtgag acgattatca actaaatttt tattagcata ttcaatggca ttaatatctt
   282781 ggtcaaaggc aattaacctc ccttttttgc ttaatctgtt caatataccc tgagcatggc
   282841 caccacgacc aaaagtagca tcaatataaa taccatctgt ttttatatta agcgcataca
   282901 ttgactcatt gaacatcaca gattggtgat attcaggcat catagtgata attgggtaat
   282961 tttattggat tttggtttat ttcactaatc gtatcaaaat aatcaaattg tttattccaa
   283021 gtatttttat tccgtacttc aaaatcatgt ctttgattac ctatgatagt tttcccatct
   283081 acatgggaat aatgttttat tgttaaagga gttagaatat gtactacttt gtctaattcg
   283141 tagttagtag tatgattaat gagttctcgt tttaattgtt ttgtgtgact gtttactaaa
   283201 gacaaagtac tgattttttc ttcccatact tgccaattct ttaagggata taacacccaa
   283261 tattcatcat ctagatgaac actaagaatc atctcaattg agtaaatttt gtcaatttgt
   283321 gtttggtgat gcgttggcat ttttaccttt tttagcacca acttatattt ttacttatct
   283381 aaacattaga gatattactg tataaagcga tacacttaat atataagtta ttatcataca
   283441 tattatacta tttttagata cttttgttta tattgtattt gttatttaaa ataatctaaa
   283501 aatcataact catcatgaaa tagttattgg tatttgacct agattatata aaatttagta
   283561 tttaagtgaa atttgttttt tgtaataatt atgtagtttt gtactaaggt caatagtgtt
   283621 attgagctta gtaatagagt aattagctac cgtttagtat gattaagaag tttttttgac
   283681 tttcaataat atttattatt gaaagtattg taatcttcat aaaaatattt tttgttaatt
   283741 tatattaaca gttttaaact atgttctgag tacgccataa tttatcatgc aaaattttag
   283801 atttcgtata tcttttaggt gtgataagaa gatgattaga aaaagtctat tttatatcgt
   283861 taagctgata atctaaactt ttaagtcttt atcctgtaga tgatatttaa ttaaatcttt
   283921 ttcttttgtt aaatttgtaa aataactgaa tgcttattca tgtttataaa taaaaataaa
   283981 tcaaataatt cctatgtttt gaggtatttg ctaaacttat atagtataca atagttttac
   284041 ttaggtacga tataagtgct tttaattgta aagagttaaa ttaaaatata gtttaattgt
   284101 agttattttt aatattatca aatgaatcaa attaactttg aacaacaaag tattgctcag
   284161 tttagtgagc gtgcttatct tgattattca atgtatgtta ttcttgaccg tgcgttgcct
   284221 tttgttggcg atggcttaaa accagtacaa aggcgtatta tttatgcgat gagtgaactt
   284281 ggtttgaaat caacagcaaa gtttaaaaaa tcagcccgta cagtaggtga tgtccttggt
   284341 aaattccatc cgcatggtga tagtgcttgt tatgagtcaa tggtgttgat ggcacaaaag
   284401 ttttcttatc gttatccatt tattgacgga cagggaaatt ggggtgcacc agataaccct
   284461 aaatcatttg cggcaatgcg ctatactgaa tcaaaattgt ctcgttatgc ggatttatta
   284521 ttgttagaaa ttaatcaagg tacggttaat tggacggata attttgatgg ttcgcttcaa
   284581 gagcctaaaa atttacctgc acaagtacct aacttattac taaacggtgc ttctggtatt
   284641 gctgtaggta tggcaactga tgtaccacca cataatttaa tagaagtagt aagtgcctgt
   284701 attgttctat tagataatcc atctattgat ttagatgata taatgcagac tattcaagca
   284761 cctgattatc ctaccgatgc tgatattgta tcctcatctg cagatcttag acagatttat
   284821 gatacaggct atggatcggt taaaatgcgt gctgtttatc aaaaagaaaa aggtaatatt
   284881 gttattgaag cattgccttt tcaagtatct ggtgctaagg taatttcaca aattgtagta
   284941 caaatgcgtg caaagaaact gcctttagtg gatgatatta gagatgaatc agaccatgaa
   285001 aatccaaccc gtattgtcat tattctgcat tctaatcgat ttgatgttga tgcattaatg
   285061 ttacacttgt tcgctacaac cgagcttgag aaaaattatc gtgttaatat gaatgtgatt
   285121 ggtctggatg gtaaaccacg tgttctacca ctaattccga tgctcaaaga atggttaagc
   285181 tataggatgc aagttgtgac taatcgttta acctgtcgtt ttgataaaat tattgtgcgt
   285241 ttgcatattt taaaaggttt gttgattgct cttttaaata ttaacgaagt aattgctgtt
   285301 attcgtgagt atgataagcc taaactagtg ttaatcaatc attttaagtt gaacactatt
   285361 caagcagagg cgattttaga gctaaaatta cgccatcttg caaaattaga agaagttaga
   285421 attcgaactg aacaacaaga attagtatta gagagaaaac aattagagtt attactttca
   285481 agtaattcac gtcttaagag tttgattaaa aaagaactaa agattattat taaagatttt
   285541 ggcgatgagc gtagatctaa cattaaaagt aatgtaaatg ttgctcaagc ttttagtgag
   285601 gataatttag tgcttgctga agatgttact gttgttctta gtaataaagg gtgggtacgc
   285661 cgtgtaaaag gtcatgatat agatccaacc acacttaatt ataaggcagg tgatagttat
   285721 ttgactagtg tgaaaggtaa aagtaacaag atggtaattt ttattgattc aacaggtagg
   285781 tcatattcat tactggctca ttcattatct aattcacgag gacaaggaga gccattaaca
   285841 ggaaaattaa gccccccttt aggggctcaa tttattgata ttataatggg taaaacgagt
   285901 caaaatatct tgttgtcttc tgatgtaggg tatggtttta ttgctacttt tgatgattta
   285961 ctgtcttcaa gacaaactgg aaaagttttt ctttctttgt ctaaaggtgc gcaagtgatg
   286021 cgtgttatta atgtggatga tgtagataat cagttagttg cattagcaac aaatcgagga
   286081 cgtttattaa tattctcaat atctgaatta cccatgctat ccaaaggtaa gggaaacaag
   286141 ttaattcaaa ttcctgtcaa tagtgctaag actagacaag aatttgtggc aagtgtttgc
   286201 attttatttg aaactcaaca actaagagtt aacgcaggta agcattattt gaccattaag
   286261 tttcaagatt taaataatta tataagcaat agagcgtgtc gtggaaagct tttgccaaaa
   286321 ggttatcaaa acgtttcctc cattaaagta attgattaaa tcaaaatatt ttggataagt
   286381 taataatttc cctatcaatc cagtgtgtaa ttatcaacag ataataggta taattattgt
   286441 ttttaccaat ttttccgaaa atgttcgtcc taaaaattgt taccgatttt gcatcagctc
   286501 attcacttag gaattatccg ggtgattgtt cgcgtctgca tggtcataat tggcaagttg
   286561 aagtaatggt tggttctaaa gaattgaata acaatggtat tgttattgat tttagagata
   286621 ttaaaaaaca aaccaagact gttgtgaaac gtctagatca tcaatatttg aataagatag
   286681 ttccttttga taaactcaac cctacttcag aaaacttagc aaaatatttt tttgatgaag
   286741 taggtcgctt aattaatatt aatgatgtca aggtcaaggc agtgactatt tgggagacat
   286801 ctagagtatc tgtcacttat tcccaaggag atttatgagc gcaactcatt tacctgatac
   286861 acaaaatagt gccgatactc gtcatattat tattgacaaa gttggtatta aagatattat
   286921 tcatcctatt acttatattg attgtgatgg taataaaatg cctacgatag gcatgtttac
   286981 tatgacagta tctttaccag aacacgttaa aggtacgcac atgtcgcgtt ttattgagat
   287041 tcttaatgaa aattcttgtg agtttagtgc gcataatttt gaccaaatta ttgataaagt
   287101 aaaagaaaaa ctcgagtcag atactgcaca cattacactc aactttcctt tttttaggaa
   287161 gaaagaagct ccgtcttcag gagttaagtc aatgatggat tatcaagtga ctttatatgg
   287221 tacgttaaat aaaggtgagg tacaagtaat gataaaagtt gtggtgcctg tcaccagttt
   287281 atgtccttgt tcaaagagta tttctaaata tggagcgcat aatcaacgtt cacatattac
   287341 tattaaagct aaagtttcta aaggaagaac tttacatata gaagatttaa ttgatttggc
   287401 tgaacgaaaa gcttcgtgtg aactttatgc acttcttaaa agagatgatg aaaaaatggt
   287461 aactgaaaga gcgtatgata accctgcatt tgttgaggat ttagtacgtg atattgcagt
   287521 tgatttaaat gcggatgata aaattagtta ttattgcctt gagtcggaaa attttgaatc
   287581 gattcataat cattcagctt atgcacttat tgaaaatcta aaatgttaaa aagaatctta
   287641 actaaaatta gtaacattcg tatcactaaa gcggaatcta ttacaccgcc aataggattt
   287701 attaaaaaat atccagtcaa gaagtcacaa tctaatttta tcatcgactc aagaaaaact
   287761 attgccaata ttatctctgg taaggataag cgtttattgg ttgtggttgg accttgctcc
   287821 attcatgatt caaaagctgc tcgagattat gcatatcgat tgttagaaat aaaaaaagaa
   287881 ttagatcggg atttatttat tatcatgcgt gtttattttg aaaaaccacg tactacgatt
   287941 ggttggaaag gacttatata cgaccctgat ttaaataata gttttgatat ggaaaagggt
   288001 tttgatttag ctcgaagttt gttattagat ttgtcaaaaa taggtatgcc aagcgcaaca
   288061 gaatatcttg atttaattac cccacaatac atatctgatt taatttcatg gggcgcaatt
   288121 ggtgcacgaa caaccgaaag tcaaacccac cgagaattag cgtctggttt atcttgtcca
   288181 gtagggttta aaaatggtac aaacggtaac atacaaattg ccattgatgc gattatatcg
   288241 gcttcaagta cacatatgtt ttggtcaatt aataaaaaag gtgtggcaaa tcgctacact
   288301 actatgggta attcaaattg tcatattatc cttcgtggtg ctgctgatgg acctaactat
   288361 agcaagcaga gtattgagaa tgctactaaa caattaataa atgatggatt attaggcagg
   288421 gttatgattg atttttctca tgctaatagt aagaaaaatt ttaaaaacca gatgctagtg
   288481 ggtgatgaaa ttgctaagca attgagttta ggttcaaata agatttttgg tgtgatgatt
   288541 gagtctaata ttaatgaagg tgctcaagca gtaggtgaac taaattcgtt agaatatggt
   288601 attagtatta ctgatagttg tcttggatgg caagatactg aaaaacttct taaaatatta
   288661 tcgttatcgg ttcaagcaag aaatacgtag tttcaagtta taatatctta cttttttttg
   288721 atagaaagtt ttgtgtaatg aaatcaatat ttgtatttaa atttgttaaa ataaaaggaa
   288781 ataaaagaaa gtctttctat tatgtctaag tatactgaga attccactaa ttttgagtca
   288841 aatttcccaa tagttactat tgagagcgag atgcgtaact cttatctgga atacgcaatg
   288901 agtgttattg ttgggcgtgc attacctgac gtccgagatg gacttaaacc ggttcatcgt
   288961 cgtgtacttt acgctatgga tgtattgggt aatgactata ataaatctta taagaaatca
   289021 gctcgtattg ttggtgatgt gattggtaag tatcatccac atggtgatac tgctgtgtat
   289081 gatactattg tgcgtatggc acaaccattt tcaatgcgta atattttaat tgatggtcag
   289141 ggtaactttg gatcagttga tggtgattca gctgctgcta tgcgttatac agaaattcgt
   289201 atggctaaac tttctcatga gttattgcaa gatttagaaa aagatacggt tgattttgtt
   289261 gataattatg atgggtcaga gtcagagcct tcagtgctgc cagcacgtgt acctaacctt
   289321 ttggctaatg gttcatcagg tattgcagta gggatggcaa ctaatatacc gcctcataat
   289381 ctaaatgagg tgattgaagc ttgtttaaaa actattgaaa atgaagatat tactattgac
   289441 gagttattag aaataatgcc aggtccagat tttccaacgg caggtattat taatggtaca
   289501 agtggtattc gtcaggctta tgaaactggt aaaggtaaaa tttacttacg ctgtgtatct
   289561 catattgaag gagaagagaa acgaagtatt attgtgactg agttacctta ccaggttaac
   289621 aaagccaagt taattgggaa aattgcagaa cttgttaaag ataagcgtat tgatggcatt
   289681 actggacttc gtgatgagtc tgataaagat ggaatgagta tggtgattga attacgtcgt
   289741 ggtgaagtac cagaagtaat acttaataat ttgtataaat taactgaaat gcaaaccgta
   289801 tttggtatta atatggtggc aattgacaag ggcataccca agttgatgac tttaaaggat
   289861 attttagaag catttattgc acataggcgt gatgtggtga ctcgtcgttc tatttttgat
   289921 ttaaataaag ccagaaatcg tgtacattta ttagaaggtt tgtcggttgc attatacaat
   289981 attgacaaca ttgttgaatt gataaagtct gcaccaagtt caacagatgc aagatcaata
   290041 ttgatagcca aaacttggcg aagttcagtg attatagaat tagttggtaa tcgtgatatg
   290101 gcaatgttta agccagaaaa tttaccaaaa gagttgggtt tacaaatgag cggtgattat
   290161 caattatcac aaaaacaagt acaagctatt ttagatttaa aacttcatcg tttaacaggg
   290221 tttgaaaaag ataaaatttt tgatgaattt aatgaattgt tagagcgtat taaatattta
   290281 ctagatattt tacaaactcc tgaaagactt atgcaagtta tttgtgaaga attaatagat
   290341 attcaaagta actatggtaa tgctcgtatg acacaaatct tagaacataa tattgacttg
   290401 acacttgaag atttaattgc ccaagaagaa cgtgtggtta ctttatccca tggtggttat
   290461 gtgaaagcgc aatctttaag tgattatcag gcacaatgtc gtggaggtaa gggtaaatca
   290521 gctactaaag taaaagatga agattttgtt gatcagctat tcattgctaa ttctcatgat
   290581 atagttttgt gcttttcatc ttttggcaag gtatactggc ttaaggttta tgatttgcca
   290641 atggcatcgc gtatttcgcg tggtaagccg attattaatt tattaccact agaaaaaaaa
   290701 gaaataatta atgctatttt gccaatctta aaatttgatg agaatcattt tgtctttatg
   290761 gcaaccagta gtggtacctg taagaaaaca gcacttacta atttctcaaa accgcgtaaa
   290821 ggcggtatta ttgctattga attaagaaat aatgaccaac ttattggtgt agaaattacc
   290881 tcaggtgaac atgatatcat gctattctca gctaatggaa aatctattcg atttaaagaa
   290941 tcagatgtac gtattgtagg gcggactgct atcggtgtac gaggtattaa attagtagat
   291001 ggtgataaag tagtatctct tattgttact aatcaagata gtccagttct gacagcaact
   291061 gaaaaaggtt ttggtaaacg tacgcatctt aatgaatatc gtgttcaatc aagaggtggt
   291121 tcaggtgtta tttctattaa aacttcagat agaaatggta aaattattgg agctattcaa
   291181 gtaaccaatg aagatgaaat gatgttaatt tctaacaaag gtattttggt tcgtgctaga
   291241 gcagctgatg tttctattat tggtcgtaac actcaaggcg tgatattgat taatatttct
   291301 aaagatgaaa aattagtctc tattgcaaag gttgttgaaa cagaagatga taaatctgaa
   291361 tctaaaagta aaaattacgt aaaataataa ttttaactgt tgtcaaaata ttttgtttaa
   291421 aagtaattac acataatgtt tgagattgtt agttttatgc aaagaaactc atgtgctaac
   291481 atttaatgtt ctctggttgc tgaaaaaact aagttagaat agcgctctat ggttaattgt
   291541 aagttgacat tggatggtgc aagataagtg agcatacctt ttgcgtcaac agcaatatta
   291601 ttacctgctt tgatcttaag ttgctcgata tccttgctat cacctgttat ccaacgtgct
   291661 gttacaatat taatagtttt aaattgacaa tgaacattat attcatattt taaacggtgc
   291721 attactacat caaattgtaa aacaccaaca gcaccaagaa tttgtgatga gttgacaatt
   291781 gggcgaaata tttgtgttgc gccttcttct gaaagctgat ttaagccctt tttaaaggct
   291841 ttagctttga gtggatcttt aagttgggct attttaaaaa tctctggtgc aaagttggga
   291901 ataccttgaa aagtgagttt ttccccttga gtaaatgtat caccaatgct aatgctacca
   291961 tgattatgaa taccgatcac atctccagcg taagctactt ctgtcagagt gcgtttatgt
   292021 gacataaagg taactgcatt actaattttt atttgtttat tggttgctac ttgtagtact
   292081 tttgtacctt ttttatattg tccactaact atacgcataa aagcaagacg gtcatgatgt
   292141 tttgggttca tattagcttg aattttaaag ataaagccgg ttagcttagt ttcatttgga
   292201 gtgactttac gaatatttga ttctctgttt tggggtgtag gagcatattt gataaaacta
   292261 tcaagtaaat tttgaatacc aaagtttgaa atggctgagc caaaaaatat tggtgtttgt
   292321 ttaccagcta gaaatttatc taaatcaaat ggagttgtag ttccatggat aagttcaacc
   292381 tcttcacgca ttttatgagc tatatttttt cctaaaattt tatcaagttg aaaattgtta
   292441 atgccgttaa tagtaatatt tttactaact tcagaattct ttcctgttct atatagataa
   292501 actttatcct caagtagatc gataactcct tttaaacgct tacccatacc aattggccaa
   292561 gtgatgggag cacattcgat attaagcatg gtttctattt catctagtaa atcaattggt
   292621 tccttacctt ctcgatctag tttattgata aacgttagaa ttggagtgtt gcgtaaacga
   292681 cacactctca taagcttgat agttcgaatt tctacacctt tggctatatc aataaccatt
   292741 agtgctgaat ctactgctgt aagggtacga taagtgtctt cagaaaagtc ttcatgtcct
   292801 ggtgtatcta ataagttgat tatatgattg tcatactcaa attgcatgat ggatgaagta
   292861 atggaaattc ctctttcttt ttctatattc atccaatcag atgttgcatg ggttttggtt
   292921 tttcttgatt tgatactgcc agctgtttta attacacctg cgtataacaa cagtttttct
   292981 gtgatggtag ttttaccagc atcagggtga gaaataatgg caaaagttcg gcgtttggat
   293041 atttcactta tcatatttta atgatcagtt taatgccggt ttcattaaac atttcttgtg
   293101 aaagtctaac actttgattc caattatcta gttcttttga attttcaatc actactcttt
   293161 taataccaac ttgaataatg cctttggcac attctgaaca aataggtaat ccgtaaacat
   293221 ataaagttgc tctatcaaga gaggtaccgg agtatgtggc attataaatg gcattcattt
   293281 ctgcatgaac cacgaatttg tacttaattt ctctatcatg atagcgttca tcagtatcat
   293341 gaattcctcg tggaaatcca ttaaatcctt gagaaagcac ctctttttta cgaccaacgg
   293401 taactgcacc tacttgtgta gaagggtctt ttgaccaggt agaaactttt tttgctagtg
   293461 ataagtaacg tttgtcccat ttatccaata tacccatatt taatgtattt taattgatgc
   293521 taaaccaatc agtactaaga ttaaagtaac tatccaaaaa cgcacaataa tttttggttc
   293581 agagatattt tgtttctcaa agtggtggtg aagtggtgtc attaggaaaa tgcgcttttt
   293641 atatagtttg tagtagccta cttgaataat cacggataag gtttctgcta caaacacccc
   293701 tcccataata aatagtaaaa tttcttggcg aatcagaatg gcaattactg ctaaaattgc
   293761 acctaaagat aatgatccta catcacccat aaatatttca gcaggataag cattaaacca
   293821 taaaaatccc aagcttgaac caataagcgc tgcacaaata ataaataatt cgttaatacc
   293881 tgttatatac ggcatattaa ggtaatttga gaagttataa ttaccactaa aataagcaaa
   293941 aatagctaat gcacctgata tgagtataac tgacataatg gcaagtccgt ctaaaccatc
   294001 agttaaatta accgcattag aacttccaac aatgacaaaa tatgataata tcaaaaaatc
   294061 aaaaacactt aacggtaata ttatatcatt aaaaaatggg atgagcaatt ggggttgagt
   294121 agttttttga gaaattaata ttatccaagt gctaattaca atagcactta atgattgagt
   294181 taaaaatttt attgaagaac ttaatccatt tgatgattta tgttttattt taagataatc
   294241 atccgtaaag ccaattgcgc taaatatgat agaagttaca ataataatcc atagatagat
   294301 attagaccaa tcgccccaaa ttaaaatact cactataaat gcaaataaaa ttaatatacc
   294361 acccatggtt ggtgtaccta ctttgattaa atgtgattta ggaccatcag tcctaattac
   294421 ttggttaata tggcattgtt gtaatctttt aataaaaata cgacccaaca taagaccaat
   294481 aaacaacgca cttagcatgg ctagtaaagc cctaatagtt aagtagttta agacgttaaa
   294541 tttggtatca aactgagtaa taaagttgat taattctaaa aacataaaat ttagcgaata
   294601 tttttaatta ataacaattc taaattaaaa tagtattttg tagaagagta ccatcaatac
   294661 tattgatata gatttgtcta aagaggataa taataattcg cttttcgtcc ttgattaatt
   294721 tacggtacct catttatcaa taagctggat aatggtgcca taacttacag taaacagcag
   294781 tgatgtattg tgtttttgaa aatttattct atcatccaaa tcaatatata aaacaacttt
   294841 gactaaattt acttttttgt ttattgtttt ttcttatttg ttttatttta atcaaatatc
   294901 ctgctttcgt tagccttgta tttggatagt tttgattaga aaatgtatcc aatttcatca
   294961 tttttgtatt acttttctaa atcataaaat tatcaatcat ctgatagaat tttaagtcat
   295021 tgtaaaaaga cattttagtc tggatatttg agtatttttc tccttgcact aaacccacaa
   295081 aattaatcac ttttagtgat gttttttcta acttaagtta gacaataata tgctacttga
   295141 ttggaatgta aatttggata taaatcctcc tctaatttag cttgcgattg taatgaaata
   295201 attaatatta atagatgtat cacataaccc aatatggctg gtgaagaaca attatgatac
   295261 ctaatctaat taaaaaagat actaacaata cggtaaaata tagcttgaat gtgttattgc
   295321 aatagaccag gagaagacta tgtctttact gattacagat gaatgtatta attgtgatgt
   295381 ttgtgagcca gaatgcccta atgatgctat ttatatgggt gatgaaattt atgaaattga
   295441 tggtaataaa tgtacagaat gtaagggtca ttttgacgag cctcaatgtg ttgaggtttg
   295501 tccagttgat tgttgtttgc ctgatcctaa tcgtgttgaa actgaagagg aattattggc
   295561 aaagataaaa tagtgaaaat tatcaatttt tgattgattt attataaaaa tttaatacat
   295621 gagttaatca aatctaaact tgtatttttt atttttaagt aaatgaagtt tttgaatttg
   295681 actaatgtaa tagtgttcag ttagaacaat ttattaacta tttttacttt ttttgcactg
   295741 aagaaatata aatatgattt actttcctat tttcttaaaa tttccttaag tgccgataga
   295801 cataaaacaa tattttcttt tcttgaggaa taacccatta aaccaatacg ccaaatctta
   295861 ccagtataag cgccaagacc tgcactaatt tcaagattat aatcattaag taagatggag
   295921 cgaatttttt cgtcatcaaa acctttaggt ataagtacag aatttaattg tggtaagcgg
   295981 tcttttttgt tcactaaaaa attaatattc attgcttcta aaccattttt taatagttca
   296041 tgattttttt tatggcgcac ccaagaattc tcaatgcctt cttctaatat cattaccaat
   296101 gattcgtgta aaccgtataa catattaaca ggtgcagtat gatgataagt acgtttactg
   296161 tctccgttcc aatagttcat gattaaatta aggtccagaa accaactgtt aacagatgtt
   296221 tttcgtgtgt tgagtttttg aatggcacgc ttaccaaagc taataagtga aatgcctggc
   296281 atggcggata aacatttttg cgtgcctgaa taaattgcat caatctccca ttcgtcaaca
   296341 tataactcag ttccacctaa agaagtaact gcatccacaa tagtgataca gtcatattgg
   296401 tgtgcaagtt tacataaggt tttgacatca gattgagcac ctgttgaagt ttcagcgtgt
   296461 acaaaagcaa caatattggc atttgggtta ttttttaaag catgttctag cttgtcagta
   296521 ctgattgctt caccccaatt atctttaaca ataattgcct tgcctcccaa gcgagtcaca
   296581 ttctctttca tacgcatacc aaatacgcca ttaatacaaa taatcacctt atcgttaggc
   296641 tcaactaaat tagtaaagca agcttccatt ccagctgaac caggtgctga tataggcatg
   296701 gttaatttat tatcggtttt aaagatagtt tttaagcctt ctttgatttc atccatcata
   296761 gctataaaaa taggatcaag atgtccaata gtaggttttg ccatagcgga taagattctt
   296821 ggatgtacat cagaaggacc tgatcccatg agagttctta ctggtggatt aaatgattgc
   296881 ataattcttt tattctttaa taaatttaaa gaaactatta taattgctta tatatgacaa
   296941 ttgttaatca attaactcgt gccttcccta agggtattgt acttacgtct aacgaaaata
   297001 cacgaccatt tgaatgcgat ggtctaagtg tgtacagaca aaagcctttg gcggtagtat
   297061 tgccagataa tgttatgcaa attaagcaag tattaaaaat ttgcaagatt aataacatac
   297121 caattgtaac acggggtgca gggacgggtt tatctggcgg ggcgatgcca cttgaaaaat
   297181 ctattgtgtt agggttgtct aaattaaata aggtgaaatt aattgatgtt gaaaatcaat
   297241 tagctgtggt tgagccaggt gtaaggaata ttgctattag tgaagcagtg gcacaatacg
   297301 ggttgtatta tgctccagat ccatctagcc aaattgcttg tacaattggt ggtaatgtgt
   297361 ctgaaaattc tggtggagtg cattgtttaa aatatgggtt aacagtgcat aatgttgaag
   297421 caattagaat gttaactatc gatggtgatg aattaatatt atcttgtcaa gatgatgggt
   297481 tgggactatt ggcactaatg aatggttctg aaggtttgtt aggtgttatt accgaagtta
   297541 cagttaagct tacgccaaat cctgcatttg ttaagatggt aatggcaggg tttgattctg
   297601 ttcgagattg tgctaatgca gtgactaata ttattaaggc aggtattatt cctgctgggt
   297661 tggaaatgat ggacagtttt gccattaaag cagctgaagg atttgctcaa gtgggttatc
   297721 ctttagatgc taaggcgtta ttgctttgtg aacttgatgg tatacaaacg caagttcaat
   297781 tagagcttga taatgtgtta aaaattttat caggagcatc gactttaaaa gtatctgaaa
   297841 gtgaagaaga acgacttaat ttttggaaag gacgtaagtc tgctttttct gcggtaggta
   297901 cactatctcc tgattattat tgtatggacg gcactattcc gcgtcgttat ttggcagata
   297961 tgttggaaaa aattcacaag ttgagcaaga aatatcaact tagagttgct aatgtttttc
   298021 atgctggtga tggtaattta catccactta ttttatatga tgctaatgtg acaggagagt
   298081 tagaaaggac tgaagaattt ggcactgaaa tcttaaaact tagtgtggat atgggaggta
   298141 caattacagg cgagcatggt gtcggtgtag aaaaattaaa tgctatgtgt catcaattta
   298201 acacgcaaga attagaaatt tttcataaaa ttaaacaagt ttttgatgag gattcattgt
   298261 ttaatcctgg taaagcagtg ccagaattac atcgctgtgc tgagttgggt gcgatgcata
   298321 tacatcgtgg tgaattgcca tatccagaac tagagcgttt ttaatggatt cgagacttca
   298381 acagttacaa actttagtta aggagtctag tagtttacat attaaaagta cattgctaga
   298441 ttattctggt attgtggaat attatgctga agaattggta attagtgtta aggcaggcac
   298501 atcaattgaa cagattaaaa aacaacttaa aaaaaacaat caagccttat ctttttatac
   298561 tgataatgat gatataagta ttggagctgc ttatgctcaa ggggctcaag atttgtcaga
   298621 ttgtgtgtta ggtgtgaaaa ttattgacgg cactgggacg tatttaaatt ttggtggtca
   298681 ggtgatgaaa aacgtagcag gttatgatgt ggcgcgttta ttagttggtt caaaaggaaa
   298741 gttagcttta attatgcaaa ttagctttaa ggtaatgcca gctatttatg ttaatcaatt
   298801 aaccccacct attaaacgta aaaataattc agtattacat aaacattttg agaaaaaatt
   298861 aaaacaagtt tttgacccta gagggatttt taactaatgc aaacgataaa aatcagcaat
   298921 atggaagcta ataatattat tagaaaatgt gtacattgtg gattttgctt ggctacttgc
   298981 ccgacttatc aattattagg taatgaatta gactcacctc gtggacgtat ttatttgatt
   299041 aaatcagtct tagaaaatca tcatttttct aagaaaagca ttgtccattt agatcgttgt
   299101 ttaacgtgta ggtcatgtga aactacttgt ccatcaggtg tagaatacgt tcaattagta
   299161 aatattggac gtaaacttgt agaacaaaaa cgtccacttt ggcagaaagt atatagatat
   299221 tttatacgtc aatttttaac tacacctatt ttatttaatc caattggatt tatttttagg
   299281 cattctcaaa tcaaaggaaa atctataaaa cctattataa gaattggtac ggttttgtta
   299341 ttaggaggtt gtgttcaacc tattattgcg cctaatatta accatagtat taaaaatatt
   299401 ctagcaaaat taggctatga aactatagaa accccacaaa aacaatgttg cggggctatt
   299461 gaccaacatt taagcgttaa tcatgacgct ctgattcaaa ttaagaaaaa tattgatact
   299521 tggcttaaag ttaaggctga aatgattatt gtcagtgcta gtggttgcgg attaatgatt
   299581 aaagattatg tatctatgtt tgaaaaacta gacccttatt atcaaaaagc acaacatatt
   299641 gttaataaaa ccaaagatat tgctgaattt ttagctgata aaaatttaaa tcagcttaat
   299701 ttagaaaggg ttaatattgt ttatcatgaa ccttgtacat tacaacacgg acaacaatta
   299761 ggaggattgg ttagttctat tttaaattca cttggttatc aacaaactcc tgttgttgat
   299821 tcgcatttat gttgcggttc tgcaggtacg tattcaattt ttcagccaaa attatcacaa
   299881 caactaagag ccaacaagtt aaaacattta caaatagcga acccccaaat gatagttact
   299941 gcaaatattg gttgtttaat tcatctgcaa aaaaaagcaa aaatccctgt caaacattgg
   300001 gtagaattat tggacaatta ggtttaataa attgatataa atacctatga gaagaagaag
   300061 aaaattagag cataaaactt ataagttaaa tatagagtca ttttctcatg aagggagagg
   300121 gattgcacat tttgaagata aaataatttt tgtgagtgat gcgttaccgg gtgaattagt
   300181 gattgctaat cgtacatttt catgtgcaaa atttgaagag gctgatgcta aagaaatatt
   300241 aaaaccagca gacaatagaa tgaaaccaaa atgtgatgta tttggtattt gtggtggttg
   300301 ttcatttcag aacttatcta gtgaagacca aatacaaatt aaaagtagat ggctaaaaaa
   300361 ggtatttgcc agacaggcta aagttgagcc ggaaacttgg ctaaaatctc ttcaatttca
   300421 aagttggggt tatcgtcgta aagctagatt aggtattcga tatgtggcta agaaagacaa
   300481 ggtattgatt gggtttagag aaagaaaatc ttcatttatc actaatatga gtcgttgtga
   300541 agtgttgcat ccatcaatag gggaacatct tgaagtgctt gctaattgta ttgaaagact
   300601 tagtattaaa tctagtatcc cgcaatttga agtggtaatt tctgagagtg gtatagcact
   300661 tattttaaga catcttgaat ctttgagcgt aaaagatgaa aaaatattag cagattgtgc
   300721 tcaagaattg aacattactt tttatactca aagtggtggt ttagatagtg ttaagccatt
   300781 agatgaacct actatactaa cgtattcaca ttctaattat aatattatta tggaattttt
   300841 acccactgat tttgttcaag taaactttaa acttaaccaa caaatggtta gtctagcagt
   300901 agaattactt gaacttaatg aatctgataa ggtgattgat ttattctgcg gtttgggtaa
   300961 tttcactttg ccaattgcaa gatatgctaa atatgtagtg ggtattgaag gtgatttagg
   301021 attggttgaa agagcaaagt ataatgctga aaaaaatagt attaataatg ttgactttta
   301081 taggtcagat ctatgtaaag aagtggtagg ttttgaatgg tttaaaggaa agacttataa
   301141 taaagcattg attgatccat ctagatctgg tgcaattgaa attgtagaat tgctgcctaa
   301201 attaggcgta acaagattgg tatatgtatc atgtaatcct gcaactttag ctcgtgatac
   301261 gcttaagtta attaaacttg gttttacgct tgaaacagca ggagtcatag atatgttccc
   301321 tcaaacttct catgtggaat ctattgcttt atttgttaaa cgataaacat taatattaac
   301381 attcaaattt ttgattattg ctaaaataat gtcttgtata aatcttgcta tattttaatt
   301441 ttaatcaacg gtatgataga ggtttaagtc gtcaattgga cgatttaaaa ttagtgaaaa
   301501 tatcaataat aatgaaaact gggaattata cttattacta gaatacgaat aggtaaaatt
   301561 tatttaaaat aatcatttaa taaacaaact agtagagact ggatattaat ttgaatttaa
   301621 tagtttgata attctgattg ggagttttaa taagaatgaa ttttttgtct ctataaaata
   301681 ttttattggt gagaaagatt acagtttaga gtgtgaaatt attttaattt gttacggcag
   301741 caattattgt taaaatattt aattgagttg acttttgcca gtaaataata ggtctatgaa
   301801 tgatttatta tgagatatga aactcttaaa gagtaagtta attatggact tgattaactt
   301861 atacttactt atgttgttta tacttaaata gatgataagc ccgcatggtt ttcagttaaa
   301921 tgaattaagt agattctaca taactatttg aagtgtgtag atgttatttt tagtgatgat
   301981 tcttctatga aaggtgtata ctttattcaa gatatacttg atatagtaaa aacattattg
   302041 gacagtggtt gtgatttagt gtttatatgt aatgatttag aattggttat gtaaattatt
   302101 gataaaaatt ggtgcatgag tgaaaaatta caatcaatgt aaggttttta taaatttaaa
   302161 cctgataaaa taaaatatta gaaaaattta gcaactatta gagatttatt atgaataatg
   302221 ataacaaaca aaggtttgaa attaggtttt tagctgtagt tagaaaaacc ctcattgctg
   302281 ttgctaaaga tactattact cggccaggat tgaaacatcc gcttagtaaa gtaacacaag
   302341 aaatgataac tgattgttta gatattgtaa ctagcagaca aattgctatt gaaaaatcct
   302401 caggcattca tactaatatg aaaccggttt ataccgataa gcaaacggtg caaagtttct
   302461 caattgatga tttaaagaaa accttaaatt aagcagttta ttttggtaaa tttatatagg
   302521 ttttggtttt attaaatcgc aaaattttat tcaaataaat agaaaggatc tatgctataa
   302581 ttaactaata agtttctact ttattgttat tgatttatca ttattttttg attttttata
   302641 tgatagaacg gtataggcta gataaagatg gtattaattt atccatattc taactacctt
   302701 aaggaggtat ctaattctat aataataatt caattttttt gttggttggg tttatcttta
   302761 catgagtatt aagaaagtta gtagtgtaac aaggtgagct attcagctat ataaattcta
   302821 aatttgcata agaactaatc aaccatttta tactgcctgc ttgtttaaat tttatctgta
   302881 ttctagaact atccccttgt ccttcaaaat ttaatactgt tcctaatccg aatttagggt
   302941 ggttgactaa agcaccaata tgtaattgat tatcagattt aggtgtaatg ctttgattaa
   303001 aaatattatt attattgtaa ttttttattg ttatatcaaa tttaacttta attttattta
   303061 aatattcatc tggaatctca tttaggaaac gtgaaggatc agcgtacaaa aaatgtccgt
   303121 gtaaaaatcg tttcatggtg taagatagtg acagtttttt catggcacgg gtcatgccaa
   303181 cgtagcataa tcgtctttct tcatctatta aatgtggttt atttttgctt tgcctgtagg
   303241 gggataaacc ttcttccatg ccgcttaaga atacataagg aaattctaac cctttggctg
   303301 aatgcatagt cataagttgt acattttgat tagtaagtgt attagtatta cccccagaat
   303361 ctattgatgc taaagaaata aatcctatta tttcattcat atcattgttc tgtttatatt
   303421 gtttagccgc agttattaat tcttctagat tttctttttt gttgctagtt ttatcattag
   303481 aataatgcgc cattaatcct gacatattaa gtaagtttac tattttttca gataaattta
   303541 agttttttgt atcatctttc attttctcaa ttaggttggt aaatccattt aatgcattag
   303601 tagtacgagt tgacagtgta gatgatactt gtatggttgc ttgaaaaaga ctgacatggt
   303661 tattttgtgc aaatatacgt attttgttaa ttgttgtatt tccaatacca cgagttggaa
   303721 aattaaccac acgttcaaag gcaagattat catctgagtt ttctatcaaa cgtaaataac
   303781 ttaaagcgtg tttaatttca gcacgttcaa aaaattttaa accaccataa ataatataag
   303841 gaatattgta ttttatgaga acctcttcaa agatacgaga ttgggtatta aggcgataca
   303901 gaatagcaca atcattgggt aatacgccat tagtgattaa tttctgaata ctactgacga
   303961 catagtctgc ttcgtctatt tcagtttgcg cctcatacat atcaattaat tcaccatcga
   304021 tagcattagt ccaaagagat ttacccatgc gactggtatt atgagcaatc aaggcgttag
   304081 aagctgttag aatattattt gttgaacgat aattttgttc taaacggatg gttttaatgg
   304141 gaacaaaatc tgtgcataat ttagtaatat tctcaatatt tgcaccgcgc cagccataaa
   304201 tagattggtc atcatcgccc acacagaata ctttattatt gccactaaat aataatttaa
   304261 tccatttgta ttggatcata ttagtgtctt gaaattcatc aattaaaatg tgcttaaagc
   304321 gatttttata atggttaagt aagtttacgt tattttttaa taactcataa ctacgtatca
   304381 acagttctgc aaaatcaatc aattcatttg ttttgcagtg tacttcataa agctcaaata
   304441 ctttaagact ttttttaata aaatagttgt aactagagtc aatatcatgt aagtgaatac
   304501 ctttattttt ttgattgtta ataaactgct gaaccttttt aataggaaac ttagattcat
   304561 ctatattatt ttctttcatt aggtttttga taatgcggaa ttggtcttgt gcatctagga
   304621 tttgaaagtt ataagttaat tgagcttgtt cataatgagt gcgtaataat cggtgtgcca
   304681 aactatgaaa tgttccagtc cacatacttg taataggatg ccttaatagc ttacttaatc
   304741 tttcacacat ttcagtagcg gctttattgg taaaagtaac ggctagaata gcatcaatgt
   304801 gaatatcttt ttgtgtgatt aagtaggcaa ttctatgtat gagaactttg gttttaccac
   304861 ttccagcacc tgctagtatt aaagcgtttt tttcattatt tagtgtaact gattggcatt
   304921 gtttgtcatt tagaccattt gttatttcag ataaattcat tatttttttt cttgtcttat
   304981 ggggttaaat ggttataata ttatccttct cttatgtcat tgagaaatga attggcataa
   305041 gtaaacaaaa ttataaacat tatttaagga gtgtcaataa tgacttacta tgcaggcgtt
   305101 aaaaaaatgg aagaaatggg tgtaaacgat aactatatac agggttgggt agctggtttt
   305161 ttaaataatc cagaaattga agagcaaaga attactaatg agtggaaatc aggttatgaa
   305221 gatggtaaag agcatacaga cgttaatttt ataaattttt gctaaatata tggaaaataa
   305281 ctggcaatat tatgctagat atacccttaa aggcgctaat aaaagtaacg ttttttttaa
   305341 gacaaagatg tttaaagact gcacttttcc tattaaaatt ccaatggaat ttgcacgatt
   305401 aattgataaa agaaataagg atgatccttt attaaaacaa gtcatcactc caaaaaattt
   305461 atcaaaaagt acaaatttta gtttatcacc attagaagat gaaaaatact ctcctgtggc
   305521 tggactgata cataaatatc caaatagggt tttattaatt gcatcgcaag tgtgtgcgat
   305581 tcattgtcaa ttttgtttta ggcaaaactt taattatgtt gagcatgatg ctattagcaa
   305641 ttgggttgag atccaaaatt atattattaa cgatgtaaaa attaatgaag taatattaag
   305701 cggtggtgat ccgttgagtt tgagtgatga taaactttcg acattgattg ataatattgc
   305761 acatattgaa catatcaaaa cactacgtgt tcatacgcgt aacgctgttg tagaacctag
   305821 cagaataact agaaaattag tagaaatatt taatcaatca agattaaata ttgtgatagt
   305881 gctacatata aatcatgcac aagaattatc tgttcaattt gcacaaaaaa tcatagaatt
   305941 aactcgtgtt actttgctta gtcagtcagt attattaaga ggtgtgaatg attcaataga
   306001 agtattgact gaactttgct tgagtttgtt tgatttaggg atattaccct actatttaca
   306061 tatgttagat aaagttcaag gtgcacagga tttcttagtt aaagacgact atgctatcca
   306121 attacatcag caattaaaga gtaatttaag tgggtatcta gttcctaagt tagtgcgtga
   306181 tagcagtagt tattccaaag attggctatt ttgaaatggc tttttctaaa tctttcatgt
   306241 tcatttcacc tatttggtaa tcaactaaat taccatttgg cccgtaaata taggttgttg
   306301 gcataccaac tatttcgcca aattttttaa attgagttct atttttatca ttaaaaagga
   306361 caatagggta atttaccatg aatgtatcag taaactccat aatagctatc ttatcggctt
   306421 gctcatagtt aagtcctaga ataatgattc tatctttgtt cttttcataa aatttaataa
   306481 aagttggaat ttcttttaaa caaggtgggc accaagttgc ccaaaagtta attactaagt
   306541 attttccttt ggtggattta ttagtatata tattgtcatc aagatcggtt agataaaaat
   306601 taggaacttt gatctttctt tcttctcgcc atatatcatt agcagatttt acaatgtcat
   306661 taatattgtt tgcttgagca atattcaaag ttacaaatag taagcatata aagctaaatt
   306721 taataatttt attgcttaat tgaaatagat aatttgtagg tataatggaa ttttttgtca
   306781 tatttattta gctatgagta taattattta tcacaatcca aaatgttcta aatcaagaac
   306841 aacattagct attttagaac aaaaaaatgt tgattttgaa ataattaaat atttagaaaa
   306901 tccaccaact ataaatgaac tcaagcaatt attaattgat ttaaagcttg aagctagatt
   306961 attaatacgt aaaggtgaac ttgaatataa agaaaagggt ttagatgata agcacttaac
   307021 tgaagatcaa ttaattagtg ccatggttaa aacaccaaaa ttaattgaaa gacctattgt
   307081 aagaacaagc aaaggggtag tgattggccg tccacctgaa aatatttttt ctattctatg
   307141 aaacgaataa gacttattta tagagccgct ttagtcaata aataaggtcg atatatgacc
   307201 tttacgtgtt tcaatgttag agtagtaaac atcatccaag tttttaacca ctgaattttt
   307261 aactatatct acttgtaata agtcttgact ccatgctttt atgtttgtaa gcctgtcaaa
   307321 cgataaagtg ttgttggtaa atttattaat ccagcttaaa cgcataaata ttggtgcaaa
   307381 agtagcatca atgattgaaa aatcgtcgcc attaaaaaat tggctattgt ttttaacagc
   307441 ttcaatttta ctaagtttat caaataaaga tttttttgat gtgtagaatt tttccttatc
   307501 acctgtaatc acatcaaata aatcatcaaa tagggttgat gaaaaatgaa tccatgaacg
   307561 atttttagcc tttttaatag ggtcactagg atgtagattg gttttgctaa tatcattaat
   307621 aaattcagta attacagagg attcaaagat aatcttatca tttgctttta ataatggcac
   307681 tttcccagtt ggggagattt gtttaaacca gttaggtaaa tttatcgagt tgatataatt
   307741 taattcaaaa gcaagttctt gcttatttaa cagaataata gcacattgtg caaatggaca
   307801 aagtttaaag ctaattagtt ctagtttcat aattcctcga attgttattg tgttgttacc
   307861 tatgataagg gtgattaatg gggtaatgaa taggattaat aaattttttt aacactagca
   307921 gttattaaat tagagttttc tgtagcttta ttaaataact tatcttttag ttttttaata
   307981 gtattattaa taacttttaa ttgttgttct aaattcataa ggcattaata taattaatga
   308041 tagaatctgg taatagtcca gataaattct tttgactttt tattttacct tgaatagtgc
   308101 ttgaagaaat attaagcatt tgattatttg caaaaaagat aaatcctgtc ttttgttttg
   308161 ttaaatcatt gattatatta gttaatctaa aaccatattt tttttgatac gttaagatac
   308221 caggtctgga cattattact agatgacaat attgataaaa attttgacac tcttcccaac
   308281 tgctaagtgt gttaaaacta tccatcccca tgattaaaca aatagaatta ttttgatatt
   308341 ttgattgtat gtatttgagt gagttaatag tgtaagagtt tttattttgc ttaatttctc
   308401 tagtatctat tgagagtgtg ttaaattcct taatagctaa atgtaacata tctatacgtt
   308461 gattaatact aaaattaagt tgttttttat gtacgggttt gtcacaaggc attaaaaata
   308521 atttagataa tctaagttta tctttaagtt gggcagcatt ttttagatgt ccgtaatgaa
   308581 ttggatcaaa tgatccacca aaaaaaccaa ttattttaaa caacttagaa tgtaaacttt
   308641 tttgcaatac tcataacata tccttaattt ctgcttgggt tagtgggcct gtaggataag
   308701 gaatttttcc ttgttgcata ctgtttacgt aattaacaaa atcatcctcg ttgtcaagta
   308761 ataagaaagc atttccttgt ttttgctcac ccattgttgt gttaattttt gagccgtagt
   308821 catgtccaca atgtagcata acatcattat ctatatattt gagtttttgc atggagttaa
   308881 ataattcttt aatattacca ccaggtaatg aacaatgtcc tgccccataa acaaacaaag
   308941 tatctccagc aataatatgt ctatctaata aataacaaat accaccagca ctgtgtcctg
   309001 gcgtgttaat aattttagct gttgtgttgc caataaaaat agtgtcgttg ttttcaactg
   309061 tatcaggtaa attattaatc tttaaataat gaatttcatt aacacctact gttattttag
   309121 caccagttgc ttctacaatt tcatcaacgg cattggtatg gtcaaagtgc caatgggtta
   309181 gccaaatatc agtgagtgtg tagcctttat cgtgtattct ttgaataaat aatggtgcat
   309241 tccatgctgg atcaacaata gcacaggttt ttgtactatg gtcaaagata aagtgaattg
   309301 agtcttctaa aacaccaatg tgatagagaa tttctagtgt ataggttttt tctttaaagg
   309361 tttgtatatt catgttatta ttttaacaat tatgtcttga ctattttaac ttagagatta
   309421 taatttaaat tttttgttta taggttagta atttaataat gttttgtggg gctatagctc
   309481 agttgggaga gcacgacact ggcagtgtcg gggtcagcgg ttcgattccg cttagctcca
   309541 ccataagtaa aaatattatg tcgccttcgt ctatcggtta ggacacaagg ttttcatcct
   309601 tgtaagagga gttcgattct cctaggcgat gccatatttt aagtaagttt tgatagatta
   309661 ggaggtatta ccaccaaagt aatactcata aattcttgat tggtatagaa gtattataat
   309721 atccatactt tgatagacat tgagagtcta gttatattac tttaaacatg tagttactga
   309781 agtattacgt gggagtaaga tcatagacaa aaattaatcg acaaggcaat ggatggtatt
   309841 aatctagtgt actagctttt gtctgaccac tctctaaata aaatttatag gtttgttaat
   309901 attattattg taaatgtgat agctatgaca cctaaagcga ctgttatttt agctaataca
   309961 gtccaaattt ttgaacccgt gtaacgatta gcagcgttcc acgtacctat catttgacat
   310021 acgttatatg ttaaagccgc taatatggta ataataacca gtgctataga ttcagacatc
   310081 tcgactccta gcattattat ttgtccaata agtcctacta atacaccata gaaccaatat
   310141 gttttagcta gaccaaaatc accatcaatt aactttttaa agaaaacttt ttgtatttct
   310201 tgagaatcat ccatatatta attcctatta tttcgtatta aatagttgtt ccagctgata
   310261 aggcctaatt gtagactaaa ttgaatagta ccttacaagg ttttaataaa gtattaggag
   310321 gtgtaactta ataatataag tcaaatcata gcaataattg ttactatatc tagatttgat
   310381 ttaagaataa taatataaaa aaatttaata gtattacagg gctatatcta ttatttgtag
   310441 aggatatata gagtatatgg attataacaa agattaattg ttattagcac agctaataaa
   310501 tcagattata caatagagaa taattactaa atttatattc gtaatagtaa tagtagaagt
   310561 tataattttt tcatatagta ttatggtatt ctggtagaaa gaatgattga ttaaagtacg
   310621 gtatcggtaa tctgttttac tttatcaaaa gtaaagaaag tatatgttat ctttgtttat
   310681 cggctataat tctaaatttt atcttatgaa aaaaggagtt tgattttttt aggcgtgatt
   310741 ctacattgat aaaatagtat ggttttttat aaaaaaccat actattcttt tgtctgtttg
   310801 taaaatattt agtctattcc cctaaattta tccattaaaa tgcttctgtc gcgttcgtct
   310861 agtctggccc aggaccctag gatttcatcc tagtaacagg agttcaaatc tcttacgcga
   310921 cgctatttta tatctacgtg agtgttgtat caacatgagc ttattaagta ttattattcc
   310981 aaatcgcttc attaatcaac gggttgatgt tgcaatggca caaatgttgc ctaattattc
   311041 acgtactaaa attacctact ggataaagtc tggtaatgct ttaattcatc gtaaaacttt
   311101 taaacctaaa gaaaaagttc taggcggaga gatggttaat ttattaatta aaactaaaaa
   311161 agccaattcg tggctagcag aagatgccgc cattgatgtg gtatatgaag attcagagat
   311221 tattattgtt aacaagccag taggtttagt aacacatcct ggtgcaagca attggacagg
   311281 aacacttgct aatgcattgt tacattatga ttcatcttta gccaatcttg atcgagctgg
   311341 tattgttcat cgtttggata aaaatacttc aggattaatg gttgttgcac gtagtgaata
   311401 tgcacaaaaa tatttaacta agcagttaca aactcatagt atttcacgag aatattcagc
   311461 cattgtatat ggctatatga tttctggtgg tagtgttgat gcaccaatag gacgtgatcc
   311521 taaggataga attaaacaag cagtagttaa agatggtaaa tatgcgctta ctcattatcg
   311581 tattattgaa cgtttcacac accatactca tgttaaggca attttagaaa cagggcgtac
   311641 tcatcaaatt cgagtacatt tatcatttat tggacatcca cttattgctg atccaatata
   311701 tggcggtaaa gtttattttc caaaaaaagc agataaacaa ctaacaaagg cacttaaaaa
   311761 cttcaatcgt caaactcttc atgctaaaaa gcttacgctt actcatccaa tatctggtga
   311821 attaatgtcg tggaaaatgc cattaccaca agatatgcaa gatttattac aaatattggc
   311881 taaatttgat tcgtgctgat tagaattgta aattagatat taattaaatt attgagcata
   311941 ttactttttg ttatagttgt ttttctttat tgtttttgag cgtgccactt gcactaaagc
   312001 tcatctcttt agtggatgta ttaagatggt aataatgtag gggtttttgt ttacgttgtt
   312061 tttgttgtat cacacatcct acaactgtaa actcaccttt aagttcaata tcatcatatt
   312121 gtgtatttaa gcatatcaaa aattttcttg aaccacgttc aatatattgg cgaaaatata
   312181 tctccatatc gtatcgtaca acagtgtaag catgattatg aattttcata ctagggtcaa
   312241 taataacaat acagttctca ctaaattctg gtatcatgta tttacctaaa ttttgcagtg
   312301 cgaatggctc agagttagtt gaacaatttg tgttaaatat ctcttggggt gtgtctaagt
   312361 ctgacatttt ttacaataga atgttgatcg ttgattttgc acaaacttaa ttattatacc
   312421 tttacaacga taacattttt tatttttaca gccatataca gataaatttt gtgtgaaata
   312481 tccaggattg ccattaactt gaacaaaatc ttgtaaagtt gtaccgcctg cttcaatagc
   312541 ctgagttaag atatttttaa tacattgtgt taaaacatta tatctagttt tggatatact
   312601 gccagccttg agtttgggat taatacctgc cataaataag ctttcgcaag catagatatt
   312661 gcctacacca actactattt tgttatccat aataaaagct ttgatgtttt gttgtttgtt
   312721 tcttgatttt tgatataaat atccatcata gaatgatgtt tttaatggct caactcctaa
   312781 tgagtctagt agtttatgtg agccatcttt tgaaaataac actgcaccaa aacgtcttgg
   312841 atcttttaag cgcatacttg ttccattttt taattgtaat tcaaaatgtt catgttttaa
   312901 tagtggtgtg tttgtattaa ccactttaat tgaaccgctc atacctaaat gaattattaa
   312961 ggtacctact ttaaacttaa ttaataagta tttaccacga cgatcaattg tgctgattaa
   313021 ttgattagtg agcgttgttg ataagtgttt aggaataacc caacgtaaat tctctcgatg
   313081 tagtatcgct ttgtttactt tttgattgat aatcaaagat gtaagcccac gtttaatggt
   313141 ttcaatttca ggaagttctg gcataaaatt atttcaaatt aaatagaata acctattata
   313201 attatcaact ttaacaacta tggagaaaaa tatgtttgat cgtattaatt tagttcagtg
   313261 caaaatcctt ttaggcttca ttctatcagt tattatattt tttagtttta attataaaat
   313321 agtagaggcc cagaacctaa cacattatgg tttaatagta tggctacatg ttttagcagg
   313381 tattgtttgg attggtttgc tttattactt taattttgta caagttccag ctatgggcca
   313441 agcattatca gatactaatg gtcctggtcc agcagctatt ggcaagtata ttgctcctcg
   313501 tgctttattg tggtttcgta tgtcggcaat aactacttgg attttaggtc tagtattatt
   313561 agcaacaaaa gatgctattc ttagtgcgtt tatgttagaa cctacttttc aaattattgg
   313621 cattggtgca tggatgggga ctatcatggt atttaatgtt tggtttatca tttggccaaa
   313681 tcagcaaaag attttaggtg tgaaatctgc aagtgataca gcaattgtta tagcaaagaa
   313741 aaatgcagca ttagcatcaa gcgttaatgt gattttatct attccaatgt tattaactat
   313801 gcttgcatgg cactaaatta agagttgtgt aatttataaa gtatttatct ttcattggta
   313861 ctttattgct attttaacaa tacagatatt tgttttatgt tcacataaca tattctgact
   313921 ttaccattga aggtggtttt tagattttca tatattttat atttttgtag taaatttgta
   313981 tattttgtat cttttttgta gagaaatatt tattacttaa aacacgtgtg tataatttgc
   314041 aacatctttg tgttacttgc aaagtaatta atgccacagg ttaaagattt cttttggcgt
   314101 atttttttaa atttttggag ataaaatatg agaaaacagt tattaattgc tgctgttgca
   314161 gcaacaatgt cagtagctgc tacagcggat atttcgatca cgggtgatgc ttatatagat
   314221 tttgctaaac aaaaaattgg agcagctgat actgcaaata ctaatcacga tagtcagcgt
   314281 actcgtttaa aagtagttgg ttctgcaggt ggtgatgcta aggtgactgc tgtcgtacgt
   314341 aatgatggtg caactcgtgc aaatgataat gatattgata gtagtaaaaa aggtcttcat
   314401 atggatagtt tatatttaac taccaaagta gggcctgtta atgtaaaagt aggggattat
   314461 tggggtacaa ttggtttagg tgctcgttct ttagatgctg ctaggtcaaa tgcattatct
   314521 gcatcaacta aagtaggcga ttggaagtta ggtttattta ctgctgatgg ttctagtgat
   314581 gatggttctg atacaactaa tgtaagtgct tctggtctat taggtccagt ttctgttgga
   314641 ttagtgcata atcctggtgg attcacaaat tttactgcta aaactacatt taatggtatt
   314701 ttgtttgctg ttgacaaatg gaatgataaa agaagaaata ttattcataa cgatacaact
   314761 cttattcata ttggcggtaa agttaatcac tttacgtggg atttagcgca gatcaaaaat
   314821 gatcaagctt ctgatatgac tgataccagc atcgttacta atggtaagtt tgcgccatta
   314881 ggttctatgt taataggtag atctgctcgg ggtggtacag caactgctgt tgctgatgtt
   314941 agtcatttta gtgaaatctt aggtgttgca gttagcacta aattagcagg taatacagtt
   315001 aaagctatct atactaaaaa cactatgttt ggtgatgata aagtaacagg tacagagtta
   315061 atagttagtc gtcctttagg tggtactact ttaacagcta atattgctaa actttctgat
   315121 gtaaatacta ttgtgaatgg taatgctact aatacaggtc ttagacttga tgttaagttc
   315181 tagattttat agtggtgtaa aaactagatt aaatttttaa aagtttaatc tagttagttc
   315241 tagaacccct agtcttattt taaggctagg ggtttttatt tcttgtattt gttttaagtt
   315301 gaaaaccttt ctgtctgata aaattcaata gaaaggtttt caacttaaaa caaataaaaa
   315361 tatgaaggtt agaataactc taaaagtgag cggtgtagat gcacaaagtt ttttgcaggg
   315421 acaattgagc aatgatattg tttccattgg agaaaatgag tggcaattga atgcgtattg
   315481 tcagcatcag ggaaaagtga ttgctctgtt ttgggtcact aaatataaaa atgattttta
   315541 cttaaatttt cctaaaagtt tgcaagataa aatcttcaaa catctgcata tatttgtatt
   315601 aatgtcagat gttgaaatag tacaaacctc ttttaatact taccccccta ttgatgtaat
   315661 gaaacatcct gaagtgtatt taataactag tgaaaaattt gtaccacaag agttaaattt
   315721 agatattaat gaggttgggg ttaatttttc taaaggttgt tatcctggac aagaaatagt
   315781 tgcacgtttg cattatttag gtaaaccaaa gcgtcgtatg cggttatttg aatgtgaaca
   315841 aatactgaaa gtaggcgata aattaattgc acttgattca aaatcagtaa aggcatcagg
   315901 catagtagtg cgttgtataa aattatatgg taaattattg tatttggcaa cgattgaggt
   315961 taaatatcaa gatagcgata ttatagcgaa taactctaat gacgccaaat tcacaaggat
   316021 taaaaatgat taaattatgt acacttttgt tcatgctttt atctatggat gcttctgcaa
   316081 ctagcgagcc gccgctagat ctaactattc attgggtagg ttatacctct cttattttat
   316141 ttgtattggc ttatatttta gtaatggtag aggaatttac tcattttaga aagtctaaac
   316201 ctgtgattct agtggcaggt gttatttggg gtttaattgg ttggatgtat actagccaag
   316261 gattaccata ttttgctgaa gtagcgctta gacataatat attagaatat gcagaattat
   316321 tcttattctt attagtggca atgacttaca ttgaggccat gcgagaaaga catgtattcg
   316381 aagcacttaa agtttggtta attaataaag gcttaacttt tagacaactt ttctggttaa
   316441 cagggttttt agcttttttc atttccccaa ttgctgataa tttaactaca gcacttatta
   316501 tgggtgctgt ggtattagca gtaggtgcag gtaatcctcg ttttattact atttctttta
   316561 ttaatattgt tgtagctgct aatgcaggcg gggtatttag tccgtttggc gatattacta
   316621 cgctaatggt atggcaaaat ggtattgttg ggtttgctca attttttagt ttgtttgtac
   316681 catctctgat taacttcgtt gtacctgcat ctattatgca tttttctatt aaaaatgaaa
   316741 tgactacaaa taatcaaagt aaagttaata ttaaattagg tggtattatt attattattc
   316801 tttttattat tactattatc acagcagtta gttttcataa ttttttacat ttaccaccag
   316861 caatgggaat gatgacaggt ttgagttatc ttatgattgc tgcttatttt attcgtcaat
   316921 ctgagtgcaa gttacaacag gaagggtttg atgtatttag aaaagttgca aatgcagaat
   316981 gggatacctt attgtttttc tttggagtaa ttgtaagtgt tggcggatta gggtttatag
   317041 gttatttaac gttagcttct gaagcaatgt atttatcttt aggagcaacc tatgctaata
   317101 ttttaatagg tgttttgtct gctattgtag ataatattcc agttatgttt gcagtattaa
   317161 ctatgaatcc tgatatgtca ctaggtcagt ggttattagt aactcttaca acaggggtgg
   317221 gcggtagctt attttcaatt ggttctgctg caggtgtggc attaatgggt caatcaaacg
   317281 ggctttatac atttctatca catcttagat ggacaggtgt gattgtatta ggttatggtt
   317341 taagtattgg cgcacatata ttaatgaatg ctgctttatt tgatgtacca gtttgagtct
   317401 tatttattgg ttgatattgg caatactagt attaagtggt gtttgaacgg taaagttaat
   317461 tcagctttta ttacacaatt taacataact caattaccaa aagtagataa aatttttgct
   317521 agttgtgtgg gtgattgtta tatattagag gatctaaata atactcattt tgttaaaact
   317581 gaacgtgtat ttaattctgt agaatgtggt tatcaaactc cttctacatt aggctctgat
   317641 cgttggttgg caatgttagc tagtattgaa cattatccta aacaaaattt gcttattatt
   317701 gatgcgggta gcgcactcac ttttgactta gtattagcta acggtaaaca ccaaggaggg
   317761 cttattatgc ctggtttgag tgtattaaga cgtagcttta ctcaattttc taataatatc
   317821 caacagttgt ctttaggtct tactgcaaac aatacccaag aaggctggtt aattggtact
   317881 agtcagatgt tgatgagtgt tattaacaca caaattgaac aacatttgaa taattatagt
   317941 aatttagttg ttgtgttgac aggtggtgat gctaagataa ttgcattaaa gcttcatcgt
   318001 caagttaaac ttcatcaaaa tttagtgtta gaaggtttgt ctagctatgt gcaagcatat
   318061 aaaaggttgc actcagtctt ggtataattt acttatttaa tttaagtaaa tataaataat
   318121 gcaagacaga cgggttttat caggtatgcg acctacaggt caacttcatt taggtcatta
   318181 tcatggcgtt ttgaaaaatt ggctagtgct tcaaaatgaa tacgattctt acttttttgt
   318241 ggctgattgg catgcattta ctacgcatta ttcagacaat atgaatttaa atgtgaatgt
   318301 tatagaaatg gtagttgatt ggcttgctac tggtattaac ccaaatactt caacaatttt
   318361 tgtacaatcc aaggtgcctg aacattcaga attacatttg ttgctttcta tgtcaacacc
   318421 tttgagttgg ttggaacgag tgccttcata taaggatcag caacttaaat tacatattaa
   318481 agatttagca acttatggat ttttaggtta tccattattg caaagcgcag atattttaat
   318541 ttataaagct ggacttgtac cagttggaga agatcaagta gctcatgttg aattcacacg
   318601 tgaggtagcc agacgtttta atcatcttta tggtcgtgaa gttgattttg aaaaaaaagc
   318661 tgaaattagt attaataaaa tgggtaaaaa acaagctaaa acgtatcgtt tactacgtaa
   318721 aacctatcaa gaaacaggtg atgatgaggc tttaatcaaa gcgcatgctt tgttacaaca
   318781 acaaaatatt actctgggtg atagagaaag actttcaggt tacattgaag gtataggtag
   318841 aattatctta cctgaacctg aattattatt aactaaagca tcaaaaatgc ctggattaga
   318901 tggtcaaaaa atgagcaaat cttattgtaa tacaatttcc ttgcgagata cccctaaaca
   318961 aatacaagtt aaaattaaac gtatgccaac tgatcctgct agaattaaaa taattaatac
   319021 aggtaaccca caaaagtgtc cagtgtggaa actgcatgaa gtgtattcaa atgaatcaac
   319081 ctgtgactgg gtagttgaag gttgtactaa agccaaattt ggttgtatag aatgtaaaca
   319141 acctattatt aatgctattg aagaagagtt aactcctatg caagaacgta ttgctaagta
   319201 tcagtcagat ccggaactta ttaaacaaat tatttttgaa ggttctgaaa aagctagaag
   319261 tattgctaag gaaactatga tagaagtgcg ggaagcaatg ggtattaatt actaatcatg
   319321 gctaatagac tacaaaaact tattgcaaat gctggttatg gttctcgtcg ttgggtggaa
   319381 cgtttaattg agcaaggacg tattgaggtt aataataaaa ttgccattat tggtgataag
   319441 actgaaataa ctagtcttgt taaaattgat ggacggaaaa ttaatttaag tcgctatgtt
   319501 gaacaagaaa caaaagttat tattttgaat aagcaagcag gggttatttg ttcaaataga
   319561 gacgataaag gacgtaagag tgtttatagt ttattaccta aagagtcacg ctggattatg
   319621 gtgggacgtc ttgatttaaa tacatctggt ttattacttg ttactaataa tggcgattta
   319681 gctaataaac ttatgcatcc tagctcagaa attgacagag aatatgctgt tagggttttg
   319741 ggacaagtga aaaataagga tttaaaaaaa cttactcaag gtgttgtttt tgatgatggc
   319801 ttttctaaat ttaatcaaat aacatttagc gggggaaaag gtgctaatcg ctggtataaa
   319861 gttgtactta gagaaggtaa gaaacgtgag gtaaggcgtt tatgggaagt tttaggattt
   319921 aaggtatcac gtcttatccg tatccgtttt ggagaaattc gtttgcctga taatcttaag
   319981 gctaatcaat atgattactt aaaaactgtg caaataaagt tattatttaa tgctgtggag
   320041 taatattaat ttttaatatt actttatttt tatactttaa ttttttatag gtttgtaaat
   320101 aatctctttt attctagtag tggattatct gttttcaaaa tttagtacta tcacgtataa
   320161 ttatgtttct aatctttatt ttttgagcgt taatgtctga ttataaatct agtttaaatc
   320221 ttccctccac tcagttttct atgaaggcaa atcttgctaa tcgagaaggt aagtttttaa
   320281 aaaaatggca aaatgataga ctttatgatc aaattcgcaa acaaaatcag ggcaagccaa
   320341 aatttgtttt acatgatggt cctatttatg caaatggtga tattcatatt ggtcatgcgg
   320401 ttaataaggt tttaaaagat ataattgtta aatcaaaatc tttatcaggt tttgatgcac
   320461 catatgttcc aggttgggac tgccatggat tgccgattga gcttaatgtt gaaaaagaat
   320521 atggtaaagt aggcattaag attgatgtta atacttttag atacaaatgt agagaatatg
   320581 ctgatcatca agtaatgagg caaagccaag attttcaacg tttaggtatt ctaagtgatt
   320641 gggataatcc atatttaacc aaagatttta aatatgaagc tgatgttgtc cgtgctttag
   320701 gtcaagttgt taaaaacgga catgtttata aaggtcataa gcctttacat tggtgcactg
   320761 aatgcggttc tgctttggca gaggctgagg ttgagtataa aaataaacaa tcagaagcaa
   320821 ttgacgttaa atttagaatc attgaggatt cggtctttaa tgtaaaaaaa ccagtttcag
   320881 ttgtgatttg gacaacaacg ccttggacgt tacctgctaa tgaagccgta gcgcttcatt
   320941 cagagttgaa ttatgtgtta gttgatattg gcagtgaata cttattactt tctcaatcct
   321001 tagtagtgaa ttcaattagt cgttatgata ttaaagttac tattggtgaa cggatgtttt
   321061 ctagtagtga attagaagga ttaaaagtac aacatccgtt ctacgataag caagtaccta
   321121 ttattttagg tgatcatgta actattgatt ctggtacagg tgctgtgcat attgcacctg
   321181 cacatggtca agaagatttt attgcgggat taaaatataa tttacctatt gattgtccag
   321241 tagatgctaa aggtgtattt tttaaagaaa ttttactttt aggtggtcag tttattttta
   321301 aagctaatgc tagtgtgatt agaattctta aagagaccaa cacattagtt aagcatgaat
   321361 cattaacgca ttcctatcca cattgttggc gacacaaaac tcctattatt tttagaataa
   321421 cgtctcagtg gtttatctct atgcaacaaa atggtcttag agatatcgtt aatagtgaaa
   321481 ttcaaaaagt acagtggata ccacattgga gtaagaaacg tattgaactg atggtggata
   321541 atcgtccaga ttggtgtatt tctcgtcaaa gattttgggg tgttccaatt actttatttg
   321601 tacataaaaa aacaggagag ttacatccaa atactcaaat gttgtttgtt tgtattgcaa
   321661 atagaatcga acaagaaggt attgaagctt ggtttaaatc tgacactaaa gattttattg
   321721 gtgatgatgt gaatgattat gataaaatta cagacatact tgatgtttgg tttgattcag
   321781 gcatgagtca ttttgtagta ttaaaagtaa gaaaggaatt atctaatgtg gctgatttat
   321841 atttagaagg ttcagatcag catcgaggtt ggtttcaatc atcactaata tcttcagttg
   321901 ctattaataa aaaagcacct tataagaatg tattaactca cggctttgtt gttgataaag
   321961 acggtaagaa gatgtctaag tctcttggta atatcattag cccccaaaaa atagttaata
   322021 acgtaggggc ggatatttta cgcttgtgga ttgcaagcac tgattatacg ggagaaatga
   322081 ctgtatctga tgaaatttta aaacgttctg ctgattcata tcgacgtatt cgtaatacta
   322141 tgcgttttat gctagcaaat atgaatggtt ttactcaaaa gaatttagta gatacgaaag
   322201 caatgttaga cctggaccga tggattgttg ctaaaacgca aaaaatacaa gaagcaatta
   322261 ttgagaatta tgatacttac caatttcatt atattgttaa gtctattaat aatttttgtt
   322321 ctaacgattt gggtggtttt tacttggata ttattaaaga tcgtcaatat actacacaaa
   322381 aagattcacc agcaaggcgt agtgcgcaaa ctgctttgta tcatattact caaatgatgg
   322441 tacgctggtt gagtcctatt ttaagtttta cttctgagga aatttggcaa gaattagcac
   322501 caaataagaa gagtattttt ttgcaagagt ggtatctcca agtagacact attgacaatg
   322561 ttgtatttga tgatggtatt atttatggaa ctatgattag ctcacatatt tctcaagaac
   322621 aacgtgaagg acttgagaaa tctgatgata tttttacaag tattaatata gtaaggataa
   322681 tttctcctac tattcgtcaa gcaattgaaa agcttagaaa agataaagtt ttgggcgctt
   322741 cattagaagc ggaggtggat atatattgta atcttaaggt taaagaaaaa ttatcaaagt
   322801 ttggtgaaga gcttagattt atgtttatta cttctgatgt tcgtttacat tcttttgaag
   322861 aaaaacccaa taatgccatt gaagtagata gcgatgtatt gcaacaagtg gctattgttg
   322921 ttgtaaaaag tgagcattct aagtgtgtgc gttgttggca tcatagaaaa gatgtaggca
   322981 gtaataataa gtatttagaa ctttgttgtc gttgtgttga gaatgtagat ggagatggtg
   323041 aagtaaggaa atttgcttaa atgaaaatac ttaatcttga cttgggatat aaatcctatc
   323101 caatatatat tggtcagaac ttattgttaa aaggtgagtt attgacaaaa catattagtg
   323161 gcaagcaagt catgattgtt actaatacga cagtggcacc tttgtatctt aaaaaggtac
   323221 aaaacttact tttatcattt gaatttgcac aagtaatttt gccagatggt gaaaaatata
   323281 agacacttga tacggttaat tgtattttta gtgcactact tgaaaagaga tttgaccgta
   323341 gttgtacatt aattgccctt ggtggtggtg tagtaggtga tatgactggc tttgtagcgg
   323401 ctagctatca acgtggtgtc aattttattc agattccaac cacgttatta tcccaagtag
   323461 attctagtgt aggtggaaaa acaggtgtta atcatatgct tggtaagaat atgattggag
   323521 cttttcatca gccaaaatgc gtactgattg atatatatac gcttgacact ttggatagtc
   323581 aacaatactc atcaggtatg gctgaagtaa ttaagtatgg tttattagta gaatatttaa
   323641 attttttcaa ctttttgcaa gaaaatatta aagatttaat ggatagaaaa cagtccttaa
   323701 taattgaaat gatttatcaa tcgtgtcaac ataaaatcaa tatcgttgct caagatgagt
   323761 tagaaatggg taaacgtact ttattaaatc ttggacatac ttttggtcat gcaattgaaa
   323821 atacgcttgg ttatggtact tttttacatg gtgaggcaat ttcagtgggt atattaatgg
   323881 caacaaggct atctcagctt gaaggatatt tgtctagtaa acaagttgct aagattcaag
   323941 atttattaga aaaagccaat ttgcctatct ctattattgg taaaataaat gcttctgctt
   324001 ttatgaaagc aatgctagtt gataagaagg tgattaatgg caatattcgt ctgattttat
   324061 tgaaaagatt aggtcaagca tttatctgcg ataattataa taatcatcta ttagatcaag
   324121 tggttaatga attttgccag taggataata tgacggataa aaataaacta aaggttggag
   324181 atgatgaagt aatgattact tctagtattt cagatttaga aaagatgctt gaaagtgttg
   324241 aaaaacatgc agatcaacgc actgacacta agtttgaaag gttttttttg ccagcacttg
   324301 cagtatttgg cgctattatt atggggttct ttgttgtaat ttactcaatt acttcggata
   324361 tgacacgttt agctaattca atggatccag atatgggtga taatatgtca tctatggtta
   324421 aaagtattga tagcttgtca tatactgttg gaaaaatgac tacttctgta gcttatatgc
   324481 aaaaagattt tcaacaagtc aataaaaata tgaatattat tgctagcaag cttgataatt
   324541 tagattctat tgcagcagat ttaacgcaag taagtttgaa gatgaatgct ttagagccaa
   324601 tgcttattaa tatggagaag atgaacaaaa atatggcaat catgcaaaat tctatgcaat
   324661 ggatgcggcg tgatttaaat attttacgct cctcattttc taaaccgctt agaattttta
   324721 atagtattcc gatgttgtag ttatgtcatt atctgaaaat caggtaagtc aaattgctca
   324781 tctagcatgt ttatcattaa atgaagcaca acttaaggat aacacacaaa atttaaatac
   324841 tattactagt ttatttgaac aattggctaa tattgagatt gatggtgttg aaccaatgtt
   324901 gcatccatta catatgttcc aacgtcttag agaagatgtt gtttctgaga aagagcagtt
   324961 agcattgttt caatcaattg cgccaaaagt taggaatggc tattatttag tgcctactgt
   325021 tattaaatag tatgcataca aaaactattg ttgaactgta taaaggtctt aaaaataaag
   325081 atttctcttg tgttgaatta acgcaatact atttaagtcg tattaaccaa tcaaagctga
   325141 atgcttttat tacagtaact gatgaattag cattagtaca agctcaagta gcagatgata
   325201 aaattgcatt aggtaacgca agtatattaa caggtattcc atatgcccat aaggatattt
   325261 tttgcactaa gggcgttaaa acctcagcgg gttctaaaat gttagatacc tttatagcgc
   325321 cttatgatgc aactgtgagt cagaagctta atcaaatgaa tttagtaatg ttaggtaaga
   325381 ctaatatgga tgagtttgca atgggttcta gtaatgagaa ctcgttctat aacgcggtta
   325441 aaaacccgtg gaattattta aaaataccag gtggttcatc aggtggttca gcagctagtg
   325501 ttgctggcgg gttaagttgt tttgctacag ggacagatac aggtggttct attcgacaac
   325561 ctgcaagttt atgtggtatt acaggactaa aacctactta tggtcggata tcaagatatg
   325621 gcataattgc ttatgcatca agttttgatc aagcggggat aatgactaaa acatcacaag
   325681 atgcagctat tgtattaaat attatggccg gatttgacga aaaagattca accagtgctg
   325741 aacaaaaagt tccagattat acgactaatc ttaataattc gcttcaaggg ttaattatcg
   325801 gattaccaaa agaattcttt ttatctggct tggataatga agtagctaat aatattatgt
   325861 ttgctgttaa agaatttgag tctatgggtg cgattgttaa agaagtatcg ttacctaact
   325921 cagtctatgc tattcctact tattatatta ttgcatcttg tgaatgttca tcaaatttat
   325981 cacgtttaga cggcgttagg tacggatatc gttctaagga gtcgaaaaac ttagaagatt
   326041 tatatttaag ttctcgctca gaagggtttg gtgaagaggt taagcgtcgt attatgatag
   326101 gtacttatgc tttgtcaaca ggttactatg atgcttatta tctgaaagca cagaaagtac
   326161 gtcgtttaat tagtaatgat tttaaaaaag tatttgaaaa agttgatgta attatgggac
   326221 cagtttctcc tacaactgca tttgatttag gttcagtgaa agatccagtt tctatgtatt
   326281 tagcagatat ttatacactt agtgttaact tagcaggctt accaggtatg agtattccag
   326341 taggttttgc acaagattta ccagtaggat tacaattaat tggtaattat tggtcagaat
   326401 ctaaactact taatatagca catcaatttc aattacaaac tgactggcac ttaagaatac
   326461 cacaggagtg ttagtatgaa gtgggaaaca gttattggtt tagaaattca tgtgcaatta
   326521 aatactaaat ctaagatttt ttcatctgct ttaactaagt atggtaaaaa gcctaattca
   326581 caggcttgtg ctattgattt ggggttgcca ggtgttttgc ctgttcttaa tgttgaggct
   326641 gttaataagg cgattagatt tggtgtggcg attaatgcac atattaataa gcgtaatata
   326701 tttgatagaa aaaattattt ttatccagat ttacctaaag gttatcaaat ctcacaaatg
   326761 gactggccta ttataggcaa aggtaagatt gaaatcatcc ttggtaatca aaccaaagta
   326821 atctgtatca cacgagcaca tttagaggaa gatgcaggaa aatccataca tgatatgttt
   326881 gatgataata ctgcaattga tttaaaccgt gctggaatac cactacttga aattgtttct
   326941 gagcctgata tgcgtagtgc taaggaggca gtagcctata ctaaaaaaat tcatactcta
   327001 gttcagtata ttgatatttg tgatggcaat atgcaagaag gttcatttcg ttgtgatgca
   327061 aatatttcta ttcgtcctaa gggacaaaaa gaacttggta cacgtgcaga gttaaaaaat
   327121 attaattcat ttaaattttt agaacgtgca attaattttg aagttaagcg ccagaaggat
   327181 attcttgaag agggtgagaa agttgtgcaa gaaactcgtt tgtatgattc gataaaaaat
   327241 gaaactcgtt ctatgcgttt aaaagaagaa acaaatgatt atcgttattt tccagatcca
   327301 gatttactac ctattgagat ttctaatgaa ttattagaaa aagttaaaca aactttacca
   327361 gaattacctg atcagagaaa aacaaggttc gttgtagaat taggcttaag tgaatacgat
   327421 gcagatgtac ttacttccca aaaatctttg gctgattatt ttgaggtcat gcttgaagat
   327481 aatattgtta atattaaact ttgtgctaat tgggttatgg gtgaattgtc agctgcttta
   327541 aataagcatc aaattgacat ccaaaactca cctattactg caccagcttt atcattattg
   327601 ataagtcgta ttagtgatga cactatttct gtcaagactg ctaaagatgt atttaagtat
   327661 atgtgggata gtaaaaatag tgcagatgag attattaaag tcagaggttt aaaacagatg
   327721 actaatatgg tcgaaattga ggtaattata gaacaagtta ttgctaatag tacattacaa
   327781 gtatcccaat ttaaattggg taataacaag attttaggat tttttatagg taaaattatg
   327841 gagcttactg gcggcaaggt taatcctaaa caagttaatg aattacttag gaagaagtta
   327901 ctttaaaaaa gctatatctt attgtgttat ttaaatagtt aaacaactta ttttagttca
   327961 taaaaatcaa gtttaaagcg aaaataaatt ccaatagata cattattagc attcattcag
   328021 gatctagatt taattattta ttactttagt taaacaatag atggagtaga agttttaaga
   328081 tattaaatag ttatttaaag gtgtaggata aacatttatt catataatat gaatgattgt
   328141 ttaatattgt acttatctat ataagggtta acattgattg ttgttagata aagtattgaa
   328201 ataatggtgg gtttatatgc aatactatat ttagtcatac tatatttggt tattttggat
   328261 tatttgctgt gtgtgtttaa attctgcaaa taaggtaagg tacttgtctg attttatgat
   328321 tgagtatcat tattagttta tttaagatga agacattaat atgttgcatt tttaatgcag
   328381 cggcataaga aatggcaatg attatttctc attagcccgg ttaatttttt tagaagttta
   328441 caacttatag tttattgatt gagttgtatt ttgaattgat gaagagaaat ttggtttgtg
   328501 tgaaaagaca agcaagataa tgtattaatt acacaattta tggacatcaa attttaacta
   328561 tatcttatat aattacttag tataagtatt aattcgtaag tcagaagata ttgatatata
   328621 aattttattt gatttattaa gtaagctttt tgaaatttat taaggtacgt agtcttatat
   328681 ttatggaatg ctaaattgat tataatggtc tgaagtaagt tgtttttctt aaatgagacc
   328741 agttatatta aacataaatt gttgaataat tttcacaacg ggaaagacag tccattgaaa
   328801 tatacctaag aataataagc ttaataaaat atatagacca taaggttcta actgattata
   328861 ttgataagat aattttcttg gtagtaatga gcttactaca cgagcaccgt cgagtggcgg
   328921 taatggcaat agattaaaca ctgctaatat caagttaatt tgaatgccaa cctgccccat
   328981 ttcaattaga aattgagagt taattgtaat tgctagtaaa attatcatta gccatataat
   329041 cgccatgatt aaatttgaca caggtccagc aattgctacc caaagcatgt cttttttagg
   329101 tgatctaagt gcattaaaat taataggtac aggtttagcc cagccaaaaa taaatcctga
   329161 agtaacatat aaaaaagcag gtattaaaat agtaccaatt agggagatat gtttgatagg
   329221 attaagcgtg attctgccca tcattttagc gctatgatct cctagtcttg aggcaatcca
   329281 accatgcgct gtttcatgta cagtaattgc aaatagtatg ggaattgtcc aaattaaaag
   329341 tgtttgaata tcgatcatat gtaaaattga atgttttttc ttgtcattat agatgaaaac
   329401 aacgaagctt ttaatcccga ctcaaaaaga agcgcctaat gatgcaaaaa ttatctcgca
   329461 tcaattaatg attcgtgcag gacttatttc taaattagca ttgggcctgt attcatactt
   329521 gccaataggg ataagagtat tacaaaaagt tgagaatatt attcgacaag aaatgaataa
   329581 atcaggtgct caagaggtgt taatgccaat tgttcaacct gcagagcttt ggaaagaatc
   329641 tggtaggtgg aataaatatg gtgctgaatt attgcgtttt atcgatcgcc accaacgtga
   329701 attttgtttg ggaccaacgc acgaagaagt gattacgcat ttggcaaggc aatatttgcg
   329761 tagttataag caattgccaa tgaattttta tcaaattcag actaaattta gagatgaaat
   329821 tcgtcctcgt tttggagtaa ttcgtatgcg tgaatttatc atgaaggatg cgtattcatt
   329881 tcatattgac gaggcctctt tacaagaaac ttatgaggtg atgtataaaa cttattgtaa
   329941 tatttttaat cgattaggtc ttaattatcg tatagtttta gcagattctg gctcaattgg
   330001 ggggaatact tcacatgaat ttcatgtatt ggcagatagt ggagaggata ctatttgttt
   330061 ttcagataag tcagattatg cagctaatat cgaaaaagtt acttttttta aacaagaaaa
   330121 aacttgtcag tctacaatgg ttgaatcaaa agttctaact aaggaaaaaa ctagtattga
   330181 agatgtttct aagtttttga atgttaaaaa ggtaaattgc gttaaaattt tgataattaa
   330241 aattaaagat ggctttaagg ccttagcgtt acgcggtgac catgagttaa atgaaatcaa
   330301 aatacataac ttatttggtg attttgagtt ttcaacaaat aatgaaatta agaatttagg
   330361 tttaaagaaa ggctttatag gtattaaaaa tttagatatt gatttgattg ttgattattc
   330421 agccagtgtg ttgtgtgatt ttgtttgtgg tgctaacgag tgtgattatc atctaatagg
   330481 tgttaattgg caaggtatta aatttattga tgctgattta cgtaatgctg tagatgggga
   330541 ttattctcca gatggaaaag gaaagttgat gattaagcgt ggtattgagg tagggcatat
   330601 ttttcagcta ggtactaagt attctagtgt tatgaaagct aatgttattg gggagtctgg
   330661 taaagcagtc acaaccacaa tgggatgtta tggtattggt gtaactcgta ttattgcagc
   330721 ttttattgaa caaaatcatg acgataaagg gattattttc tctcaagcga ttgcgccttt
   330781 tcaaattgtt attgtcccga ttaattacaa taaatctact cgtgtaaaag cattggctga
   330841 taggctttat cagcagttta ttaaggcaag tattgatgtt ttgctggatg acagaaaaga
   330901 gcatgtaggt attatgtttg ctgattctga actacttggt attccacaca gaatagtaat
   330961 tagtgatact catgctgaca atggaagtgt ggaatataaa gctagaaata agacaaataa
   331021 aatagaagta aaatttgatg atgctttatc atttattcaa actaagatga tataaaaaat
   331081 tatgatctgg tggcaatacg ttattcctca gcattggcta tcaaagttaa tgttccgttt
   331141 tgcacgcatt aaaaatgttt ggtttaaaaa taagtttatc acttggtttg ttaagtctta
   331201 tcagattaat ctatccgagg cagtacgtga aaatattaaa gattatcaga attttaatga
   331261 tttttttact agagaattaa aaccagatgc tagaaagatt gctaaaagtt tgattatttg
   331321 tcctgttgat ggtagagtat cgaaggttgg taatatcaat agcactcaga ttatccaggc
   331381 taaaaatcat agatataatg ttgaacaatt gttgggtaat gatattagaa gtgctgagtt
   331441 taaggtaggg ttttttgcta ctatttattt atcacctaaa gattatcatc gtattcatat
   331501 gccttatgat ggcaaattaa tttcaatgag ctatatttta ggtgatttgt tttcagtgaa
   331561 tcaagttact actgaaaata tagatggatt attcgctagg aatgaacgtg ttgtatgtta
   331621 ttttgagact gaatttggtt tgtgtgcatt tattctagta ggtgctattt ttgtaggttc
   331681 aatggaaact gtttggcatg gtcaaattaa tccgcctttt caaaaacgga tacagcattt
   331741 ttcttattta aatcaaacta ttgaacttaa aaaaggcgaa gaaatgggtc ggtttaatat
   331801 gggttcaact gtgattatgt tgatgtcaaa ccaaattaat aaatttattt taaaagagac
   331861 tgaaatggtt agaatgggac aggctctaat ttagttattt taaccaattt aatagtttgg
   331921 ttagaaattt gcataatttc gattagtatg ttgttaattt ttaaactaac atcacgtttc
   331981 ggaatgcttt gtaatgtctc taagattaag ccatttaatg tttttgcgtt agtaacggat
   332041 aagtttaatc gtaataaatt atttaactct cgtatattaa ttctaggatc aactaagtaa
   332101 ctaccatctt tctgtttggt aatttcatca atactctcat tttggtttga agtgaactgt
   332161 cctacaattt cttctagaat atcttctaat acgatcatac cacgtacttc tccgtattca
   332221 tctacaatta aacctagtcg tcttttttgt tgttgaaaat gtgctaattg gtgggcaagg
   332281 ctagtacctt ctggtacaaa ataaggcttg tgaatcaatg ctaacgcatt gtcaatactg
   332341 aaattaccct tggcatatag atttacaata tcacgcatat gcaatacgcc agtaatattg
   332401 tcacttgatg tgtcgtaggt gataagccta gtatgttgta tacgttgtaa ttgttttaaa
   332461 attttatcag gtttgttaat atctatacta attaactcgt gtctaggaat cataatatct
   332521 tcgactttga ctttttctag gtcaataata ttgagtaaca ttttttgata attagaggca
   332581 ataacaggtt tagcatcgct aaccaccatt tttaactctt ctgaactaac aaggttattg
   332641 tttgtttcac tttttatact aaatgttgtc aatattattt ttgataattg agcaattatc
   332701 caaacaaaag gtttaaatat tttaattaac gattcaataa taatggagac tggtaaagca
   332761 attttttcag ggtttttagc ggcaaatgtt tttggtgttg tttctgcaaa aactaagata
   332821 ataaaagtta atgttaaaga ggctaataca attgaacctt cgccccatag tttaatggct
   332881 agtattgtag taatactaga ggcaaaaata ttaactaagt tatttcctaa taggattgtt
   332941 ccaattagac tatccaagtt attaagtaaa tgttcggtac gttttgcatt tttattgttt
   333001 ctgcttaaga ctttaagacg atagcgatta attgccatca ttgatgtttc agtactagag
   333061 aaaaatgcag aacttagtat caatccaaaa agtataatac taagccaaaa aattgagagt
   333121 gattccaatc caattgtact aacttgctat ataaagcaac aagtttaatt taaatgatta
   333181 aaagcattaa gtcctggata aactgcctgt gtgcctaatt cttcttcaat acgaagcagt
   333241 cggttgtatt ttgctaaacg atctgagcga gaaagagagc cggttttgat ttgactgcaa
   333301 gtacaagcta ccgctaagtc agcaatggtg gtatcttcag tttcaccaga tctgtgtgac
   333361 ataattgagg tgtagcgagc attcattgct acttttatgg ttgcaaatgt ttcagttagt
   333421 gtgccaattt gatttacttt aattaaaata gaattagcaa tatttctctc aataccttgt
   333481 tttaagatct tactgttggt tacatataag tcatcaccaa ctaactgaac tttatcaccg
   333541 agtttcttag ttaacaagtt ccagccattc caatcatttt catccatacc gtcttcaatt
   333601 gaaataattg gataattttc tacccatttt gctaaataat taacaaattc ttcagagctg
   333661 aatgatttat tttcagatat tagattgtaa gttttgttgt cattatcata aaattctgaa
   333721 cttgctgcat caataccgat aaaaatatct ttacctggtt tatagcctgc attattaatt
   333781 gcttctaaaa taattttaat agcatcttca tttgaagcta aattaggagc aaaaccacct
   333841 tcatcaccta cagtggtact cataccttta atttctaata ttgattttaa atgatgaaac
   333901 acctcaatac catagcgtag cgcttcctta aaacttggcg cacctacagg tataatcata
   333961 aactcctgga tatcaatatt attattagca tgttcgccgc cgttaataat attcatcata
   334021 ggtacaggaa gtttgtagtt tcccccttgg tttagtgaag catataatgg tttatgttgt
   334081 ctattagcgt tagcatgagc agctgctaac gataccgata aaatggtatt tgcacctaat
   334141 cttgatttgg ttttagtacc atctaaatca atcattgttt ggtcaatttt gcttaaatta
   334201 ttaatatcaa aaccaattaa ggtatcacaa atctctgtat taacaaattt aacggctttt
   334261 aaaactcctt tacctagata acgtgattta tctctatcac gtaattctaa tgcttctttt
   334321 tgaccagttg atgcaccaga tggaaccatt gcactaccga ttgtatcatc attaagaata
   334381 acatccgctt caacggttgg attgcctcta gaatcgataa cttcccttgc tttaatttgt
   334441 ttaatttcca tagtttgtgt gtattaatat aatcgttata tggttaaaag tgtgtttaat
   334501 ctcatttaaa atgattaatt ttttaatgct agtaatttaa gtactgttaa ttttaaagta
   334561 ttctactgtt atttgctttt agtattttta ttatttattt tagaactaga caacttatta
   334621 gtgaatttta gcaaaataat aacttatatt gataagtaca gttaaatatt tatttaaact
   334681 atccagctat agattaaggt tttttagtaa ataaatttaa gaatattttg aatgcctttt
   334741 taattagcta tagtaaaaac ttacagacat gaagattatg aatatattat atagtaatta
   334801 tcaacaagag ttagaacaat tcaaacaatg gtttgaatta tcaagcaata ccgattttaa
   334861 gaaaagtcat attatccgtt tcaaaaatat aaataaatat tagcctaaaa ggcaataaaa
   334921 taattaatac cttattagat aaattatacc aaattagaaa taagagactt tcacctctta
   334981 cggataacaa aatattatta tcatggaatg cactaatggt tcaaagcttc cttaacgcag
   335041 gtgaagcttt taatgaagaa aaatacacca aactaggaat aaacttagat aattatttac
   335101 atactcattt caataagaat aaccaacttt acagggtatc aattgactct aaacttggaa
   335161 cattagcagt attcgaagac tatgcttatt tatctaatgc ttatctatct gtatttgacc
   335221 aaactaatga taaaaaatgg cttgacagag ttattactct tgttaatgta atgaattaaa
   335281 aattttggga taaacaatac catggattta atataaatta ccatacaggc ctaaactaga
   335341 atagtcttta ttattaacat aaccatccaa atagtaagca aaattaatat ttgtatattg
   335401 atattatgta tcatagatat ttcttttatc tatttgtact ccatataaaa cattaactaa
   335461 acttccttgt atgcatttca ccatgttagc taattatttt cttttctaca aaaataactt
   335521 ttttaaactt aaaacaagcc atttgttact gctactataa ttgaataaat ttataaccta
   335581 taataacatt aagataccat aatatatttt tatataaaca atttaacatg attatttttt
   335641 taccactaca gagtatttat ttataaacaa ataagatcta tatagtgaga gtaaaaaaat
   335701 attaagacac ctacttctgt ccaataaata aaagatactg gaaattatac tgaactataa
   335761 tctttgatta atgttagcac ctgttgagga ttgtgaagct actttaagtt tatttttttt
   335821 ctaatctcag aacagtttaa aaaagaaata acacaaaatg ataattaaac aagtaaaata
   335881 tttatcaaac agtactctat taagtaaatt ttagttattt acccaaaagt tttttttaac
   335941 caattaatta actcatggtt aattaaatac aaacaaggta atagaacaag tgtcattaac
   336001 gttccaaata acaaaccata acccaatgaa agcgccatag gttgtaaaat aaaatctgta
   336061 ccgccaatgc cataagcaag tggtattaca cctgctaagg tggttaatgt tgttaacaca
   336121 acagcacgta atcgatcttt tgcaccttga gcaacccatt tataaacact catagtagac
   336181 gcaagtttta cctttaaata gttcagatga gtaaccatta ttaaagaatc gttcacaata
   336241 acccctacta atgccaatgt acccaatatt gcaaaaaagc taagtgtttc tccatgaaga
   336301 aaaaaggccc aaataacgcc aataatagaa aaaggcacgg caattaaaac taatatcggt
   336361 tgtgaatagg aattaaacaa taaaattaat aataaaaata tagaaaaaat tgccatgata
   336421 aatgcctttt taaagctatc cattgtcttt tttgtatctt tatttcctcc ttcgctagtc
   336481 atctgaattg caggatactt actaactaaa tctaactgct taagcgcttg actgataact
   336541 tcaccagaag tagttacttc atcatcaaca ctaccgctaa acatgactga acgctgcccg
   336601 ttaaaatgat taaagtttgg ttctccttta atttttttca atgaaacaaa ttgtttaagt
   336661 ggtatggggc gaccttgacg gttgttaatt tttagtaacg ttaaaaaatt ctttgactgt
   336721 ttatcactac ctaaataaat tctaaaatag acattattat cgccataacg tacgctagta
   336781 acattagtgc ctgtaaaaac tgcctttaaa taatcatcaa ctactgaaaa atcaacatca
   336841 aatctagaca ttttttcaaa atcaatcaca acctcaatgc gtgcttttcc tgattcatca
   336901 tctcgctcaa tgttatctat tccatcaata cctaataata ttttctctaa agtatcagca
   336961 gcattctgac gttgaatatt atcactacct attaaattta tttccacatc ttcaccttgt
   337021 gatggacctg gcctacttat tgaaaacttt aattcttgtg caaattttat atccttaaca
   337081 cgttttttta acttagcaag taaagattta gatgtttcta ctcttatgct agaaggtaca
   337141 agttcaatac taaacttagc tacattagta aaataatgac caatattatt ggttaatgaa
   337201 tctaaatcct cacctacaac ttctataata attttctcta cttgtttgga aatagactct
   337261 gttcgttcta aagaagtacc aataggcatg tttaatcttg catcaatact atctgctccc
   337321 actatgggaa attgtacata cttcatttga gttttagcaa aatacaaaga acctataaga
   337381 acaatactaa aaataaaaac aacactataa cgccatttca atacttctgt taaaaaacct
   337441 tcaaaccaaa cctcaatacg cataaaccat attttttctt ttgttttctc atcactacta
   337501 gcaagatgtg ctggcaatgc caaactaact tctaaaaaag aaagagtcaa agaaaaaata
   337561 actactaaag gaatgacata aataaattta cccattgttc cgctcatgaa aaacatcgaa
   337621 gagaaagcca aaatagtagt caaaattgtc gttatcacag gcgcaataac acgcttaaac
   337681 ccaagtatag tagactgata tctgtctttt cctaactgtt tataatgatg tatactttct
   337741 gccactacaa tactatcatc cactacaata ccaagtatta aaatcattgc agctagcgaa
   337801 acaagattaa tagtctcacc tgttacacct aataaagaca ccgtgcctag aagagatact
   337861 ggtaaaccaa ttgataccca aaaagccgtt ttaaacgata aaaataaagc caaaataatt
   337921 agcactaaca gtaaaccaat taaaccatta ttggttacaa tattcagtct attacgaaca
   337981 tgattggatt catctgatga ataaaaaaat ttcaagctag ttggatattt agcttctaac
   338041 tccaatactt tgtctttgac taaatcaacc gtagtaatta catccgcatg ttcttgttta
   338101 tggatactca aaataaaacc tttggtacca ttcacacgaa taatagaagt ctctttcttg
   338161 ttctcactag taatttttgc aatatctttt aaacgaataa caggtccatc aaaagttgat
   338221 ttaataatca cattactaac agcctcaatc tcatcaaact tagctaaaac aacaatagtt
   338281 ttttcattaa tatcattatt attaccaaca gtgtaacgtt tattacgatt tttaatcgct
   338341 ttaattactt gaggcaaaga taatttatgt tgatataggc tatcaggatt aactctaatt
   338401 tgaaattcac gatcaagata accctcttta ataacttttg aaacaccttt aactaacgac
   338461 aaagattcac tcatatcatc gataatatcc cttaatactt ggtaggacag gttatcgcta
   338521 ctaatattaa tttttaaaat acttttgagt gaatttttct ggtcaactat ccaagggaag
   338581 ccattaacct cttcaggtaa agacttaata cgattaacta catttctaat ttcttgcttt
   338641 aatggctcaa tatcatctac atcttgggaa agtattatga caatactaga cttcccctct
   338701 ttagaggttg aactaaattt atcaatccct gaaatacttc ttaactcgtc ttcaattaga
   338761 ttagtgacat tctgctcaac atcttcagga gaagcaccag gatatgcggt tacaatagtc
   338821 attacttcaa aatctacagc tggaaattta tccctttgaa tgctatttaa agtaaaaaga
   338881 ccaagcacaa taatggaaat cgtcaaaacc aatgctagct tcttctgttt aacaaaaaaa
   338941 ataagaatgt tatccataaa cgtttaatga aagaaataac agcagtatac cattagcact
   339001 aatactaata ataaacaaga aaagttacat tttatttagt tttttcatgc accttttcgt
   339061 tcacttactg ttaataaacg tttacgaata cgaatattat gaggtgttac ttctactaat
   339121 tcatcattat caatgaattc tagtgctttt tctagatcaa gtttaatagc aggagttaat
   339181 gatacagctt catcagtacc tgatgcacgt acattagtca attgctttcc cttcataaca
   339241 ttaatcatta aatcttgata gcgtgtgtga ataccaacca ccataccttc gtaaatatca
   339301 gtattatgtt ctataaaaaa tttcccactt ttctgtaaat taaaaatagc gtaagcgact
   339361 gcttgtcctt gattcataga gatcaaagaa ccattagaac gctgaccaat ttcccctggt
   339421 tgttgaagtt tataagtatc aaaagttgca ttcattagac ctgtgcctgt cgttgctatt
   339481 aaaaattctg ttctaaaacc aatcaaacca cgtgcaggaa tattaaagtc taaccttact
   339541 ctgccattac catctggtat catattagtt agtttagcct ttcgttcgcc taattttttc
   339601 atcatagtac cttgatgttg aatttctaca tcaaggctta aatcttcgaa cggttcacaa
   339661 attactccat caatctttct taaaataact tgtggacgac ctactgccaa ctcaaaaccc
   339721 tctctacgca tagtttcaat taaaattgac aagtgtaata caccacgacc taaaacaaca
   339781 aattcagatg gatctgatgt gttttcaacc cgaagtgaaa tattgtaaat taactcttta
   339841 tctaaacgat cacgaatatt tcgtgatgtg ataaatttac catcttgtcc agcaaatggc
   339901 gaatcattca cacgaaatgc catggaaaca gttggttcat ccacactcaa aggaggtaac
   339961 gattcaatag ttccagggtc acaaatagta tctgaaattg aaatattttt aatgcctgta
   340021 atacatacaa tattacctgc ttgtgcagaa ttagtatcaa ttttatttaa tcctaaaaat
   340081 ccttgcaaac tagtaatttt tgccttacgc ttaccaccat caacacccac aacaacaact
   340141 tgcatattct ttttaatcgt accacgagta atacgaccta tactaataga gcctacaaat
   340201 gaagaataat caagagcagt gatttgcatt tgcaatggtg catcaatatc aacttctggt
   340261 gctttaacct gttttacaat agtctcaaac ataggtgtca tatcacctga acgcgtatca
   340321 tcgtctaatg aagcataacc attaatacct gaggcataaa taattggaaa atctaattgc
   340381 ttatcagttg ctcctagctg atcaaataaa tcaaatactt gaccaattac ccaatcagga
   340441 cgtgctgcat ctttgtcaat tttattaata acaacaatcg ggttcaaacc ttgctcaaaa
   340501 gctttcctcg ttacaaaacg tgtttgtggc attggacctt cttgtgcatc tacaagtaaa
   340561 agtacactat caaccataga tagaatacgt tctacctcac ccccaaaatc agcatgaccc
   340621 ggtgtatcta caatattaat atggtaatca taccatttaa ttgcagtatt tttactagaa
   340681 atagtaatac cacgttcttt ttcaagatca tttgaatcca tcattcgatc acttgactca
   340741 aaacgagcat caaatgtttg agattgctca agtaatttat caaccaaagt tgtcttacca
   340801 tggtcaacat gagcaataat agcaatattc cttaatttag tattcatgtg tagtaggtta
   340861 ctgtaaaaaa gatattatta tctcgtaaaa tactcttcaa tattaggaat tattaatatg
   340921 tcaaaaaaag acagttcaag acgttggatg agagagcata tcaacgataa gtttgttaaa
   340981 aatgcaaaaa aagcaggcta tcgttctcgt gctgtttata agcttataga ggtaatcaat
   341041 aaagagaaat ttatcaaacc aggaaataaa gtaattgacc ttggtgccgc tcctggcagc
   341101 tggagtcaaa tggcaataaa agctgtaggt aaatctggcc aagttattgc caacgatata
   341161 ttgaacataa aacccattga tggaattgat tttttacaag gtgatttcac tgaaaacagt
   341221 gtttatgaag cacttttaaa tctcactatg aatcaaaaag ttaatgttgt cttaagcgat
   341281 atagcaccaa atataagtgg tcaaccctca gttgacattc ctaaatctat gtacttatgt
   341341 gaactagcat tagacatagc aattaaaagc ttaacacctt caggttattt ttttgtcaaa
   341401 gtttttcaag gagatggatt tgatatgttt gttgaatctt gcaggactta tttctcttat
   341461 gtcaccattc acaagccaaa agcttcaaga acaagatcta aagaagttta cttgcttgca
   341521 aataaattaa agccagctaa gttgatgtaa gtattggttt tgccaataac ccataactac
   341581 gcatgtgtaa aataactact atgaaaaatt taagtgatat tcaatccctt ataaaattag
   341641 atttaaaaaa aacagacgaa atactcatta accgtttaag ttcaaatgtt gctttaatta
   341701 atcaaatgag ccattatatt atccatgctg gaggcaaacg cttgcgtcca ctactcttat
   341761 tactttgtgc gcgtgcaact ggatatcaag gaacacatca ttaccttatg gcagtagtga
   341821 tagaattaat tcatactgct actttactac acgatgatat tgttgatgaa tctagcacac
   341881 gccgaggaaa agatactgtc aatgaagtgt ggggtaatgc acccagtatt ttagtagggg
   341941 attttctata ttctcgcgct tttgaaataa tggttgagcc taatttaatg tccattatgt
   342001 gtattctttc taaaacaacc aataatattg ctgaaggtga agtattacaa ttattaaatt
   342061 gtcaaaatga tgaactaacc gaggttgaat attatgcagt aattaaacaa aaaacagcat
   342121 gtttattcca agcggccact caaattggcg ggctattatc agctgttaat aaaactcagg
   342181 agactgcatt aaaaaactac ggcttgcatc ttggaaacgc ttttcagatt attgatgatg
   342241 tacttgatta tgagtcagac gcgaagacta taggtaaaga agttggcgat gatttaagtg
   342301 aagggaaaac cacattacct atgatttacg cactttctca tacttctggt aatgataaac
   342361 aacttctaaa agacgccatt aatcaagcag ataattctaa aatagtacaa gtgattaaaa
   342421 ttttacaatc ggttaaagcc tttgactata ctcgcaatca agcgtataaa tcagcgcaac
   342481 ttgctaagca atcactcaat ctaataccta actcagagta taaggatgca ttaatcttat
   342541 tatgcgatct ttccttacaa cgtcagtcat aaaaccatgc tttcaaatga gctaaaaact
   342601 aaaatccatc agtcatttaa aaacttaaaa gaaaacatga atggctttat tacacgtcaa
   342661 gcacaaaaca aaatgattgc tgaaatctct aagactttat caggagaata taaaaatagc
   342721 cataacattt tatgtgttga agcgccaaca ggaattggaa aaacatttgc ttacttgctt
   342781 ggtagtatcc atatagctaa agctaataaa aagaaattaa ttatctctag tgccaatgtt
   342841 gcgttgcaag aacaactgtt ctttaaagat atacctcaag cacaacaata ctgctgcgtt
   342901 gattttgaat atactttaat caaggggcgt tcacgttacg tttgtattcg taatttaatc
   342961 aacatatgtg aagataataa aaatgataac cctttatttg aatcaatgcc attgtttgat
   343021 aaaccaccag aagaatatcc attagaacaa cttagtaaaa tgctgtataa ctattcaacc
   343081 aagaaatgga atggagaaat tgacgattta atacccacaa caaatcattc tatttggcaa
   343141 caaatagctt gcaaccgctt tacttgcacg gtaaaaaatt gtgaatttta taaagattgt
   343201 gctttcttta aaactagaca aaaaattaca aaagcagatg ttattgtcgc taatcatgat
   343261 ttagttttag ctgatcttag cactggtaat accgtattac cagatgttag taaatcaatt
   343321 tttatatttg atgaagcaca tcacttaaac tcaaaagcat tatcacactt ttcattaaca
   343381 actagtactg agtttattaa aactagcgtc aagcaaacta aagaagttag tgaaacatta
   343441 tgtaaaatta gcaaacaaaa tatacctaat attaatatca aacaaattga taattatata
   343501 acagatttaa ttcaattatt agaacaacta aaatttaatg aaaacattta cttatttaac
   343561 caaggcgtta ttgatgagcc tatcaaacaa ataagtagaa atattctaac actcattgaa
   343621 attattcaaa ctaaattcac acttttaaaa gaattttgga gtgattattt aaaaaaaaca
   343681 gtcataaata aaagtattca tggccctatt aacaatatgg ctggacaatg tgaacagcac
   343741 ttactcagta ttatagcttt attttcatcc ttcttgcaaa tagatgaacc aaataaaata
   343801 ccaaattcac gttggattaa aaaaagtata ctcacaacaa gtaaaagaac taactacttg
   343861 cttaatagcg cacaaactga tatttcagaa aatctagatc accttatttg gtccaaagct
   343921 tcaggtgcca ttcttacttc agctacttta acatcactag gtagttttga acgcttgaat
   343981 aaacaattag gtttactaag aaatgaaaac caatatttac gcttaccctc accttttatg
   344041 tttaatcaag tagatcttat tattgctaaa ctgaaagcta gcccaaccca agtgtatgaa
   344101 catacacaag aaacaacatt gcaactactt aaacggctcg atagtgatga gggttcacta
   344161 gtactattta cctctaacaa acaaatgcaa atagtggcaa acttgataga taaaaaacta
   344221 aattgtactt tatttataca aggagaatat cctaaaaaaa acatattaaa aaaacatatt
   344281 aacctgcgaa aacaaggtaa aggaagtatt atttttggac tagatagttt ttccgaagga
   344341 atagacttaa aaggcaataa ccttactcat gttatcatta ctaagttacg ctttagcgtt
   344401 ccaacttcac ctattgatag aacgctagcc acctatctta aatcacaaaa taggaaccct
   344461 tttatggaaa tatctctacc tgatgcatca cttaaactca ttcaagcttg tggtcgctta
   344521 attagaacag aaactgatgt agggaaaatc accatctttg ataaccgtct gatctctaaa
   344581 ttttatggaa aactactact caatgccttg ccaaactata atataattat agaatagttt
   344641 acatatttaa aaacgccaaa aagctttgtg taacaatgcc attaaggtta atatttctaa
   344701 gcgtcctaat aacattgaaa aacttaggat ccactttgct gtatcgctaa tacccccata
   344761 attagcagaa acatcaccca agcctggacc taaattatta atggaagctg ctgctgctga
   344821 aaacgcacta acttgttcaa gaccagaaaa cataagcatt aacataatca caacaaaggc
   344881 aattacatat aaagagagaa acccccagac cgatactaaa gtattctcag aaacactttt
   344941 ttgattaagt ttaatattaa tttgtgcatt agggtgtata aattttttaa tttcctgcat
   345001 ggctaattta aacattagca atattctaac aactttaata ccgcctcctg tagagccagc
   345061 gcaagcacca ataaaactaa caaagattaa aaatactggt aacacaaatg gccataatga
   345121 aaaatctgta ctgacaaacc ctgtagtcgt taccatagaa acactttgaa atacaccata
   345181 tctaactgat tcttcaatgg ttttataata acctgtatca aacaaataac ctgatattaa
   345241 cataattgat atacccaaaa ttaacaaata agttttaaac tcagaatctt tcaaataaat
   345301 aaaaatatta tttttacgcc aaacaagaaa atgcagtgaa aaattaacac ctgctaataa
   345361 cataaatatt attgccacca attcaattgc ataagaatta aaataaccaa ttgacacatc
   345421 atgagtagaa aaaccgccaa tagcaatagt cgaataactg tacccaattg cattaaacac
   345481 atccataccc gcaaagtaat aactcaatgc acaagcaaca gtaagactga tataaatttt
   345541 ccataatgct ttagctgttt gagttagttt tggcgtaagt ctttctttag agataccact
   345601 tgattctgca tgataaagct ccataccacc aacacctaac attggcaaaa ttgcaaccgc
   345661 taaaacaata atacccatac caccaagcca ctgcagctgc tgacgataat acaaaagtgc
   345721 tttaggtaaa ccatctaatc cagaaagcac tgttgcaccc gtagttgtta gccctgacat
   345781 agattcaaaa aatgcatcac taaaggacat ttctaaagac gttgataata aaaatggcgt
   345841 ggtagcaaat aaagataaaa ccaaccaaaa actcactact actaacacac cttcacgaat
   345901 tctgaaatct ttggttgagt ttttaaaagg caaccataaa acaaaaccac ttaataatgt
   345961 taaaaaaaaa gcagttataa aatataaggc ttcattctga gcgtaaataa aatcaacaat
   346021 aataggtggt aattgagtta aactaaacaa cattagcaac aaaccaacag ttttaaaaac
   346081 aatactaaac tgcattttta acaatcatta atcaaaatac ccttcaaata acttttcaac
   346141 ttcatgaatt ttactcacgt cagtaagtac tagtaataca tgatcgcctt ctttaatgat
   346201 caatctccgt gaccccataa ttacttcatt atttctaacc actgaaccta caaccacgcc
   346261 atttggtaaa ttaatttgtt caattgtttt acctacaaca tctgaatgat acttatcacc
   346321 atgcacaata atttcaattg cctccgcttt accttggcgt aatgaatacg ccgtcatagt
   346381 atcaccttta cgaatatgtg ctaaaatacc gccaacagta atttgatcag gtgatatgac
   346441 catatcaaca tcttcacttt gttcggctaa gtcttcataa acattacgtt taactaaagc
   346501 aactgtttta tacgcgccta aacgcttggc taaaatagaa acaataacgt taatttcatc
   346561 agaatctgtt aaagctaaaa ataaatctgt attttcaata ccttcttcca acaataattc
   346621 ttcatcagaa gcgttaccta aaagcactaa tgtattttca agctcatcag caatttcatt
   346681 aacacgctgc ttattcatct caataacacg aatacgatga tctttttcta aaaactttgc
   346741 taaattaaga ccaatacgtc caccacctgc aataataata tttttataag ttctatcttc
   346801 acgtctaaat tgtttaatca ctttagaaat actagctttt ttagtcataa aataaactcg
   346861 atctccatca cgaataaccg tctcacctga tgcgggaatt gccctactat tacgatacaa
   346921 actcacaatt cgtacccatg tttttggtaa atgctcatgt aaatccttaa tcggatgtcc
   346981 tacaattgga gttcctttat aagctctagt ttctaccaat tgaaccaatc cattttcaaa
   347041 ctcaaatact tgctcagcac caggttcctc aaccatacgt ttaatataat tagtcaccag
   347101 ctcttcaggt gtaataacaa aatcaattgg aatagcatta ggtgaaaata actcttttct
   347161 atgcaaatat tctgcagtac gtacacgtgc aactttcttc tcgacttgat ataaagtatg
   347221 tgccatctgg caagccagca tattaccctc atcagaacga gtaactgcaa taaccatatc
   347281 catattttta atatctgcct cttctagaat attagggtac gaagcatgac cgcacacagt
   347341 tttaatgtct aaatgacgtt gtaaatttaa taaattagac tcatctttat caataataga
   347401 aatatcatta tcattatcta aacctaaata tttagccaat gttgttccaa cttgccctgc
   347461 acctaaaatt aagatcttca tattatttta ttttttatca atgcctaaat cttttaactt
   347521 gcgatataag gtggttcttt ctaaccctgc aaatgctgca accttagcaa tgttatgatt
   347581 attctctttt aaatggtgat tgaaatactg tacttcaaaa atatttcttg cctctttaag
   347641 tggtacatta aactcaatat tattaacatt atatctagat ttttctagta cttgttcaga
   347701 tagaatttta cgtattaatg gcaaaaaatc atgcaatggt tttttcaaaa aatcaactgc
   347761 accaaattta attgctttaa ccacatcttg atgctcagca tgtccggaca tcatcacaat
   347821 cggtgtagaa aaatcagctt gagtccattc ttctaataat gacataccat cctgaccagg
   347881 catccaaaca tccatcataa ccaagtcaaa agattggtct tttataataa ttttagcttg
   347941 attagcatta gctgcaagaa ccacgtggta attaacatct tccaatatat ccatcattgt
   348001 ttcagcatta atattttcat catcaatgat aagaatacta ccaatgacta atacatcatc
   348061 cataattctt cctttttatc ccttacaatc aaattcaatg gtaatcatag caccgtgtgg
   348121 attaatatta ctagcaaata tttttgcctt atgttgtttt atgatgttct gcacaatcgt
   348181 catcccaaga ccaccacctt gagctttagt cgtcacataa ggttcaaaca ctctatcaat
   348241 cacatgttta tcaaaaccat caccattatc tatgatactt aaacgcacaa tagcctgttt
   348301 tagtaaatac tctgttacaa ttttaacgtt taaatcacgt ccgtcaatca tagcttcact
   348361 ggcatttttc actaaattaa ttaataccct agaaatactg ttactatcta agaacaatag
   348421 tggaatatta acagccaagt ctaaatcaat attcatttta cttatatcgt cataaagtaa
   348481 aatagattgg ttaattaatg cattgagatt acaaggcatt ctttcaacct ggggtgtatt
   348541 agcataatca gcaaatgcac tcaacatggc atccatagac tgaacttgat gaataatagt
   348601 atttgtagtc ttatcaataa catctaaatc cttaccttct aaagaaatta gaaatcgatt
   348661 cctaagacgt tgggcagata ataaaattgg tgttaatgga ttcttaattt cgtgtgccat
   348721 acgcttcgcc acctctcccc aggcagcttt tttttgagct ctatttaatt tcgaaatatc
   348781 cttaattata atcacaaaac ccaaagtttc attatcattt ttaagtgccg ctccttggca
   348841 cgataataac aaatgtcgat caactaaagt aatttcaatc tcctcgctcc actcactttc
   348901 atcttgttta aatttatctt gtgtcattaa aaacaaaggt tctaaatttg aacaacaatc
   348961 aacaataata ttacattttt tacctataaa taacttctca tctttaatac ccaacattgt
   349021 gccaaccact ggattaataa ggcgtatttt cctattctga tcaagcgcaa ttacaccata
   349081 agaatattta agaattgtct ctaaatacaa attatgcgta tctaagtctt cacgagaagc
   349141 tttgatttgt ctagacatag tattaaattg ttcaattaaa ctacgtacat cttcactttc
   349201 ttcttgttta gcaatacgta catcataatt gcctttagca atctcttgcg cagcaatgga
   349261 taaattattc agtggcttca tcaaccgttc aatcatgcga aaaaccacca taatcgcact
   349321 aagtattgcc aacaatattg tagacgaaaa atcaatcata aaacgttttt gagtaattga
   349381 agtgttaatt tcaaacttaa tattttgtgc tgcactagca aatcctctaa cttgagacaa
   349441 aaatcctaaa agtcctggat cagtcgcata caccacatca ataacaaata tatcttgact
   349501 tgatacatta aagagataac gtgttgacat tttcacttga ataacatttg cggtttcatc
   349561 ttcattaatc atacgtggtt gtgcacctaa caatggctgc tctttaatca ccatacaatt
   349621 agtcacattt gctgttttag caaccatttc ttcttgagca tttaataatg taatttgaca
   349681 agcccaacct ttatcaatca aaccatcaag aaatatttgc atactttgtg cataattttt
   349741 aacatctttt tggaagctac caaaggaagt aattaaagtt agtaatcttt ttgtttgttc
   349801 agtataacgc tcatctctaa ttttttgcac accactatac aaaccattaa cctgttgaat
   349861 aaaattttga ctgaaaacat taaaagcttt ctctgaatct ttcacattat tttgaatcgt
   349921 ttgaaatgaa aacatataaa aagataagac tggcacaatc accaaaactg gcacaatttt
   349981 aacaaaagac caagtaaact tagaacctac aacatcacct ttaacatcac gtttaagacg
   350041 caatacatct acataaacat aataaacagc aaccaaactc atgatgatat taaatccaac
   350101 taaatatccc caccagtgtg caataaaatc agggttgagc cctaaataaa aagtaccaga
   350161 aatagacagt aaaaaaataa gcacccaaat ccatgctggc ggtgtcttct ttaaactcaa
   350221 atattggtta agaaccatat aaaatagtgc agataagaac catataaaat agtgcagaca
   350281 atcatatttt ttaaataatt atcgcataca tctacaaaag ttattcatta aaaataactc
   350341 aaataactcg acttattatc tatgtgtcca agtttatcaa atcactactg tagtacgttt
   350401 ataacgaaag cttatattat tctaataaca cgttttttag tatttctgaa aatatttttg
   350461 acgtgcttat aagtaattta taattaataa gctgaatatt atattttata ttgttaataa
   350521 caagtttttt aacatcttac atggtttctt tcttgctatt aaagggaatt tatttagaat
   350581 aaaattagct aaaatagtaa caaaggttat caatataatt taagttaaac acatttttat
   350641 ctgaatattc acaactaaat aaaattgaca ttgctattga taaccacata ctaccaataa
   350701 aaccaatata aaacatagaa aatcattata atatagacaa taaagttatt gttaatggct
   350761 aattattatt gatttttatt catagtaact gatcagttat tttcttagca gactagcact
   350821 ttaaatatta ctataaagaa aaactaaaaa atgcaaaata gtttaaaacc agtttcagca
   350881 ggtaatattc ctgatgaagt aaatgttatt attgagattc cagcaaattc atcacccatt
   350941 aagtatgaaa ttgataaaga aacaggcgca atgtttgtag atcgttttat ttcaacacct
   351001 atgttttacc cttgtaatta tggttttgta ccagaaacat tatcagatga tggtgaccca
   351061 actgatattt tagtgattac accttatcca ttaattcatg atagtgtcat tacagcacgc
   351121 ccaattggaa ttttatatat gactgatgaa gcaggaaaag attcaaaaat attagccgta
   351181 cctattgata aattatgtaa atcttatcat gatattaaat gtattgacga tgtaggtatt
   351241 actcttaaaa aacaaattga acatttcttt acttactaca aagatcttga agagggaaaa
   351301 tgggtgaaaa ttgatggttg gggtaattct attaaagcca aaaaagagct tcaagcttct
   351361 tttaactatt actatcaata attttttcca aattggatca ggtaaatatc ggggtaaaaa
   351421 atttaatttt ccttatacac ctactttaag acccacatca ggaagaatac gagaaacttt
   351481 atttaattgg attcaattcg agtcatacaa caaaacctat ttagatttat ttgctggtag
   351541 tggtgcgtta agttttgaag cgttatcacg tggcgctaaa caagttacta gttttgaaaa
   351601 agactataac acctatcaaa atttacagaa aaataaagca ctattaaaaa caaataaaat
   351661 aaatattttt aatcaagacg cactaaactt tttatcccat aaaagcacac aaacctttga
   351721 ttttattttt ttagaccccc cttttaataa aaattatcta ccaaaaacct taaaagcact
   351781 tatagatggt aattatatta ctttaaatac taaaatctat atagaatctg aatttaaaat
   351841 ttcagaaaac atagtaacta aatggttatc aacaaatatt caaattaata aacaaaaaca
   351901 cgcagggaaa atacactatt gcttaataac tttattacaa aactttgatt aaatttatat
   351961 tattatgaaa aaaatcgcaa tttatccagg ttcgtttgat ccaattacta atggccatgt
   352021 tgatttaatt aaacgagcta gtaaattatt cgacgagatt atcattggta tttctcaaaa
   352081 tagtaaaaaa aaagcttttt taagtataaa tgatagaatt gatacaatca atactgcact
   352141 caaagatatt aacaatatta gaatattaag ttttgacaca ttattagttg acttcgcaag
   352201 tttgaaaaat gcacaagtga tattacgtgg attacgcgct attagcgatt ttgaatacga
   352261 atatcaactt tcaggtataa ataaacatct caatcctaac attgaaactc tatttatgac
   352321 tcctaccgaa caatacgcca atatttcctc ttctttaata aaagaaatta tagcattagg
   352381 aggtgatatt agtgtttttg tgcctgcatc agtaaaaaca ttacttaaac atcgcctata
   352441 atttttttaa ccttaatcct tgaaaaaaaa aatgcccatc cctatatagg acgtatatta
   352501 aacttaagga gtaaaaaatg tcaaagatta tcggtattga cttaggtaca actaattcat
   352561 gtgtagccat tatggatggt gggagcgtta aaattattga aaattctgag ggtgatcgta
   352621 ccactccatc tattattgct tatcctaaag attctgagga ggttctagtt ggtcaagcag
   352681 caaaacgtca agcagttacc aatcctgaga atacgctata cgcaattaag cgtttaattg
   352741 gtcgtcgttt tgaagaagat gctgtacaaa aagacattga tctcgtacct tataaaattg
   352801 ttaaagctga caacggtgat gcttgggtta aagttaaaaa caaaaaaatg gctgctcctg
   352861 aaatttcagc aaaagttatt ggtaaaatga aaaagactgc tgaagattat ttaggagaag
   352921 aagttaccga agcagttatt acagttcctg cttactttaa cgactcacaa cgtcaagcaa
   352981 ccaaagatgc tggtaaaatt gcaggtctta atgttaaacg tattatcaat gaaccaactg
   353041 cagcagcttt ggcttatggt gttgataaag taaagggtga taaaaccgtt gttgtatatg
   353101 acttaggtgg tggtacattt gacgtttcca tcattgaaat ggaagacatt gatggtgaaa
   353161 agcactttga agtactttct accaatggtg atactttctt aggtggtgaa gattttgatc
   353221 aacgtatgat tggctattta gtagatgagt ttaaaaaaga ccaaggtgtt gatctaacca
   353281 atgatcctat ggcactacaa cgtctaaaag aagcagctga aaaagctaaa attgagctat
   353341 cttcttccga acaaacagag gtcaatttac cttacgtaac tgcagatgct tcagggccta
   353401 aacatcttaa tattaaaatc actcgtgcta aattagaatc attggttgaa gacttgctca
   353461 aacgtactat tgagccatgt aaaactgcac ttaaagatgc agatttatct acaggtgata
   353521 ttgacgaagt tatcttagta ggtggtcaaa cacgtatgcc taaagtcaca aaaatggtac
   353581 aaaacttctt tgataaagaa cctaaaaaag atgttaatcc tgatgaagca gtagctatgg
   353641 gagctgctat tcaagcaggc gtattaggcg gtgatgttaa agatgtatta ttgctagacg
   353701 taacaccatt atctctaggt attgagacaa tgggcggagt tatgactaaa ttaattgaaa
   353761 aaaatacaac cattcctact aatgcatcac aaattttctc aacagcagct gataatcaat
   353821 ctgcagtaac cgtgcatgta ttacagggtg aacgtgaaat atcaagtgct aataaatcat
   353881 taggtcaatt caacttagaa gggattaatt cagcccctaa aggccagcct caaattgaag
   353941 taacacttga tattgattct gatggtattt taaatgtatc tgcaaaagat aaaaataccg
   354001 gtaaaaaaca atcaattaca attaaagcat catctggatt aagcgatgaa gaagtcgaaa
   354061 aaatggttaa agacgctgaa gcacatgctg atgaggatca aaaattccaa aaactagtaa
   354121 ccagcaaaaa catggcagat gctttgatac attcaaccaa acaaacttta gatgaactca
   354181 aagatgagat ctctattgat gaaaaatcag tgattgaagc atctattacc gatcttgaaa
   354241 aagtcattaa aagtgataat aaagaagcta ttgatactaa agttaaaaca ttaagtgaaa
   354301 aagcacaact attagctgaa aaagcacaag ctaaagcagg tgttaaaaac actcctcaag
   354361 aagagaaaaa ttctgatgat gtagttgatg ctgattttga agaggttaaa gacgataaat
   354421 aaaaaagttt aacacctaaa accttcacta ataaacaaca cttgaagaag attattttaa
   354481 taataaggca aatatgtcac aaagagattt ttacgaaata ctaggtattg caaagaatac
   354541 agacgttaag caaattaaaa aagcttataa acgcttagca atgaaacacc accctgaccg
   354601 agttaaagat aataaagagt tagctgaaaa aaaatttaaa gaaattcaaa aagcatacgc
   354661 tattttatct gacacccaaa aacgtcaagc atatgatcaa tttggacatg ctggtatcaa
   354721 tggtaatgca ggtgccacta gtggcacatc atttagtagt agcggatttg gggatatttt
   354781 tggggatatt tttggtggtg gttctcaaca gtcaaataat cgtggatcag atttgcgtta
   354841 tgatttagaa attgatttaa aagaggcagc acaaggcact actgttaaaa ttcgtattcc
   354901 aaaaaatgaa acttgcgata cttgttcggg cactggtgca aaacctggta ccagtgttaa
   354961 aacctgttta acttgtggtg gtgcaggaca aatacaaata caacaaggat tttttgccgt
   355021 tcaacgtcct tgtaatgctt gttctggtac gggtcaaaga atcgaatcaa cttgtaataa
   355081 ttgtcatgga aaaggtgtag tacacaaaca aaaaacacta tctgtcaaaa tacctgcagg
   355141 ggtagataca ggtaatcgaa ttcgtttaag tggcgaaggt gaagcaggta ttagaggtgg
   355201 tcttagtggt gatttatacg tacaaattca tgttaaaaaa cacgctattt ttgaacgtca
   355261 agatagcgat ttatattgcg aggtaccaat tgactttgca actgcagtat taggaggaca
   355321 agttgaggtc cctacacttg acaataaatt aaacataaaa gtcccagcag gcacacaaac
   355381 tggaaaacta tttcgcttac gtagtaaagg aattacccat cttcaacatg gtggttctgg
   355441 cgatgttatc tgtaaagtta agcttgaaac acctatcaat cttagcaaaa aacaacaaga
   355501 cttactacaa aaattttcaa attcatgtgg taaaaaacat caccctgaat caaactcttt
   355561 ctttggtaaa atgaaatcat tttttgaata aaataaatag ttcaacctct ttattttttt
   355621 aaagaatgtt ttattgcaat atttttccca aatcttgttt taacttacaa tagtgtaaga
   355681 ttctatcaaa ccttgtccta ggtaaatctt tatctatcac tctaataatt acatcacctt
   355741 tataaatact atcgtatcaa atattataag taaaactagt aactaaagtc ttcaattttt
   355801 actatctcaa gtttttatta ccttaatact gtataattaa tagcacttaa ttcatcaatt
   355861 gaccaaataa agaatatgcc ttcttcgctt tgagagtcag catcagtagc agagaaaaac
   355921 ccgttactag tatcttgcat ttctgtcaat gtgtaatcta aagtttttta gagatgtttt
   355981 tatataaagg attctttgtt ttgtagtgct tgtcgaatta atgctttagt tgaaagtgag
   356041 ttatctttaa tgacagatag cattttttca gattctctgg ctttaaatcc aagtgcttgt
   356101 aaagcagctg atgcttgttt gatattagga ttttttttga attttatatg aatattttta
   356161 tgattttcat tgtttaattt tagtttttct aaacggtctt taagttctac aatgagtttt
   356221 tgtgctgttt ttataccaat tcctggggtt tttgctagta aagtatcatt tccatctgta
   356281 ataactttta ttagtgaatt aatgtcaaga tgagataaaa tagctagtgc tactttagga
   356341 ccaataccat ttattctaat caactctcta aataaagttt tttcatcttt agagataaaa
   356401 ccgtataaaa tatgcgcgtt ttctttgatt gataagtggg tgtataacga gagttgttct
   356461 tcatcaccca ttgcataaaa acttgacatt gagcataaaa tctcatagcc aattttatct
   356521 acttcaagta atatttcagg tgggtttttt tctaaaatag tgcctgaaag tttaccaatc
   356581 ataaccaatc atacttatta aaatagtgtt tttcaaatgc tttaatatca tttatatatt
   356641 gtaaagttaa actaatatca tcaagtccat tgattaggtg tgtttttcgt tctatatcta
   356701 tttcaaaagg gtaatttttg ttatttatat tgatactttg agcgtcaaga ttaatggtta
   356761 ttttatcagt tgaggaaaat aattcatcca ttacattatt attttgtaca ataggtagga
   356821 tgccattttt aaaacaatta ttataaaata tatctgcaaa actaggtgca ataattgttt
   356881 taaaaccata atcttttaat gcccaaggtg catgttctcg acttgatcca cagccaaaat
   356941 tcttcagtac caatagtatt tttgcatttt gatattttgg ttgatttaat acaaaatcca
   357001 tattaagagg acgtttagaa ttatccatac caatttcacc gtggtctaaa taacgccatt
   357061 catcaaataa attagcacca aaaccagaac gtttaataga ctttaaaaac tgcttaggaa
   357121 taatcgcatc agtatcgata ttagcacgtt taagtggtat tgctattgaa gtaaatgtag
   357181 taaatttttg catttattta acttctgata aataaccagc aatagcgctt gaagctgcaa
   357241 tagcagggct aactaagtga gtaaatgagc cttgaccttg acgaccttca aagttgcgat
   357301 ttgaagtact tgcacatctt tcacccactt ctaacttatc agcgttcatg gctagacaca
   357361 ttgagcaacc tgcttctctc cattcaaacc cactatttat aaaaatttta tccaactcct
   357421 cttcttcggc ttgtttttta ataattcctg aaccaggtac aactaaagcg agtttgatat
   357481 tattagcaat tttcttatct tttaagatgt cagctgcaat acgtaaatct tcaatccgtg
   357541 agttagtaca tgatccaata aaaattttat cgattttaat atctgatatt tttgtattag
   357601 cattgagatg catatagtta agtgcatttt tccagctgat tttttcggtt tgattttttg
   357661 cgttattagg atttggtaca tacccatcag ttgccaccac catgtctgga gatgttcccc
   357721 aagtaacttg cggcttaata tcttttgcat caaagtgcat tgttttatca aagtgtgcgt
   357781 ttttgtcaga atgtagtgtt cgccaatatt ttactgcttt tctccattta attcctgaag
   357841 gtgctaatgg gcgatctttg acatagttaa tggttttttc atcaacagca accataccaa
   357901 tacgtgcacc tgcttcaatt gccatattgc atagtgtcat tctaccttca attgacagat
   357961 tctgaatggt attaccgcta aattcgattg caaagcccat gcctcctgca gtgccaagtt
   358021 ggccaataat ataaagagca atatcttttg cactaacatg ttgattaagt gagccattaa
   358081 cttcaatatt aaaattttta gatttagatt gccataaaca gttagtagct aagacatgtt
   358141 caacctcgct ggtgccaata ccaaaggcta atgcaccaag tgcaccatga gttgaggtat
   358201 gtgaatcacc acagacaata ctcatgcctg gaaaggtagc accttgttca ggaccaatta
   358261 tatgtacaat accttgacga gtgtcgttca tagatatttc atcaatacca aacaattcgc
   358321 agtttcgccc taaggtttca atttgtattc ttgaaatagg atcgctgatg ctactaacac
   358381 ctgatgagcg attagttgtt ggcacattat ggtcaggtac cgctaagttg gtacttttac
   358441 gccaaagttt tctgtttgct attgataacc cttcaaatgc ttgaggagag gttacttcgt
   358501 gaataagatg cctgtcaata taaatcaatg cagttgaaat attttcacgt atgatatgtg
   358561 catccataag tttattgtag agtgttttag ccattattga tacacaatac ttgttaaaat
   358621 tacttatttt acttctttaa taaattttat gtgtggactt tgtggacagt taagatttga
   358681 taatcgagta gtgagcgacg atagacttaa gaaaatgatg aaaaggatgg tacatcgtgg
   358741 tcctgattct agtggctctt ggattgatgg tcatattggt tttggacatc aaagacttgc
   358801 tattattgat ctatctaata acgcctatca gccaatgatt gataagaatc ttggtttagt
   358861 tttggttttt aatggcacga tttataatta tcaagctttg cataagtatt taattaagca
   358921 aggttatcaa tttttttcac attctgatac tgaagtaatt atcaaagcct accaccattg
   358981 gggtgaggac tgtgttatgc atttagatgg tatgtttgct ttttgtgttt gggataaagt
   359041 tcaagaccag ttgtttgttg ctcgtgatcg aatgggtatt aaaccatttt attttaattt
   359101 aacagataaa gcttttagct ttgcttctaa tgttcaagca ctggtaacac aagaagtgga
   359161 taaaagcatt aattctgttg ccttacagca gcaactttca ttgcatgggg ttgtgccagc
   359221 acctaatacg attattaatg gagtaaataa aatcaaacca gcaaccacgt taaccattag
   359281 tggtaaaggc aaagttgttg agaaaactta ttggcatcca aagtctattc gtctaaaaga
   359341 agcattgaca gacgagcaat ttattcagcg tactcatgaa cttttaagag atagtgtttt
   359401 aaaacgcatg aatgctacag atgtaccaat tggcgtgttg ctttctgggg ggttagattc
   359461 atcactctta gtagcattga ttaaagagat agggtataac aatatacgca cattttcaat
   359521 tggctttgaa gatatcaacg gtgaaaatgg atctgagttt gaatattctg atcaaattgt
   359581 tgctcggttt aaaactcagc ataaaaaata tatggttagt aattcacaag ttctaacacg
   359641 tcttggtgaa gcagttgcaa atatgagtga gccaatggta gctcaagatg cagtggcatt
   359701 ttacttatta tctgaacaag tatctaagca tattaaggtg gtgctttctg gacaaggtgc
   359761 agatgaggtt tttgcaggtt atttttggta tgaacgtatg aaagctcaga caggttctga
   359821 tattgagcgt tttaccaagc attatgttga taggccgtat gaagaatatt tgcaaacggt
   359881 taatctaaaa tatcacagcg gaaaccatac cgaaacttgg cttcatcacg aatttactaa
   359941 ggaaaataca gatacgttta tggataaagt ctttcgcact gatgttaccc gtttagtagt
   360001 agacgatcct gtaaaaaggg tggataatat gactatggct tggggtttag aggcacgtat
   360061 gccgtttatg gattataagc ttgttgaaca tgctttgagc atgtcaccaa gtttgaaaat
   360121 gcttaataaa ggtaaatatc cacttaaaca aattgctaag ggtttgttac ctgacagtgt
   360181 aattgaccgt aaaaaaagct attttccaat gccggcactc aaatatgttc aaggtgaatt
   360241 tttagatttt atgtcagata tactaacttc gagtaaatgt attaatcgtg gtatttttag
   360301 tcagatattt attgctaaaa taatcaataa accccagaat tatatgaccc cacttaatgg
   360361 ttcacgctta tggcatttgg cgttattaga attttggtta caaattaata ttgatgaata
   360421 gaatagttat ttatacagat ggtggttgtc gttgtaatac tggtattggc ggctggggcg
   360481 tatggttgaa atatggtgat tatgataaaa aacttaaagg taatgaaaaa aaaaccacta
   360541 acaatcgtat ggagttgact gcaactatta aagcattaga agagattaaa tctaatcaga
   360601 ttggtattga tttatttaca gattctaaat atgtaataac aggtattaat gagtggatga
   360661 agaactggaa agtcaaaaat tgggaaactt ctaaaaaaag accagttaaa aatgtagact
   360721 tatggcaacg cttagatgtg ctgaataaac agcatgatgt tatttggtat tgggtcaaaa
   360781 gtcatagtaa caataagggt aatgatattg ctgatgaatt ggcaaattta gctatggata
   360841 agatcagtct gagttgaaat attagttttg aataaagaaa tcaaaatatt atgtttaact
   360901 tataattatt aatagttata agtattttaa aaattaattt tattctactg atatatcata
   360961 tagtttgttg aataaatatg tttttaacca tatattgttt tagctcttac tataaatgcg
   361021 tctagttgag aattggcaat tgaggtaaaa atatgtgata tagaaatatc tacaagtttt
   361081 gatgagaaac taaatgctag attgagttga atcttacagg cagtattatt taaagcaaca
   361141 aatacccatg agccgtttag ttgtttaaat agtccttctt taagctgcat gtcaattctt
   361201 tgatagggga ttaaggtgtt tgttgttgta aaagtttgat taaaacctcc tttgttaatc
   361261 ttaattgagg ctatgatttg attatcagat tgctttaaaa tagaagaatc tgaacaccaa
   361321 ttaagaaatt cagggtattg attaacttga ttaatcaatt gatacatttg tttacaagaa
   361381 taggaaacaa tggcattttt agaaatatga tgcatggata aaaataataa tggctaaaaa
   361441 aaataaaaaa ataagtttaa ataccattgc atttaacaaa aaagcaaggc atgtctattt
   361501 tatcgaacaa accttggaag ctggtttaag tttagaaggt tgggaagtaa aaagtttaag
   361561 agactctaaa gttcaaatta aggaaagtta tgttatttta agaagtaatg agatattttt
   361621 atatggcgca catatttcac cactgaaaag cgtatcaacg catgttaatt ctgatcctat
   361681 ccgtacacga aaattattac ttaatcgttt agagattaat cgtattaagg agaagattaa
   361741 tcagaaaggc gctactattg tagcgcttaa gctttattgg attagaggta tggtaaagtt
   361801 agaaattggt ctggctaagg gtaaaaagtc ttatgataag cgtcaagata ataaattaag
   361861 agattggcaa agagataaac aaaggacgtt aaaacaaata aattataggt tatagttctg
   361921 attgatgatt atttatttgt tttaaacgct taatttacta agaaaaatgc ttttatagca
   361981 gaagtagcta aatattttat ttttattccc ctctactatt cttatatgat taatctttct
   362041 tttataaatt aattttttga agagaaaaaa tgaacaaatt agaattaatc gatgtaatta
   362101 cgtcagtggt aaatttatct aaagtataga gatctatcga tcgtgtatta aacacatcaa
   362161 tatataatat tattaacttg aaggctagtg gtaatagtgt gctttactgg ctttggtaga
   362221 tttattgcta gaaattacac atacgtataa gttgtaaatt tatcaatagg aataatgatt
   362281 taaattagag aaatcaaaag tggttgattt taaagtaagt gaagagttat aagaaaaata
   362341 tttattaata cactgtaaaa agagtacttt atggtgcttt ctatgtctta aatttggtaa
   362401 aattttgact ctatttatga ttagaggaga tgtcatggaa cgtactttat caattatcaa
   362461 gccagatgcg gttgcaaaaa atattattgg taaaatttat tctcgttttg aagaggctgg
   362521 ttttagaatt attgctagta aaatgattca tcttgataat gatgaggcag gtggttttta
   362581 tgcagtacat aaagatcgtc cattttatgg tgagctgctt gaatttatga cttctggtcc
   362641 gattattgtt caggttttgg aaggagagga tgttgttgct aaacatcgag aaattatggg
   362701 cgacactaat cctaaagaag ctaattctgg tactattcgt gctgattttg caaggtcttt
   362761 agatgaaaat acagtgcacg gctctgattc tttggaaaat gctgttattg aaattaaata
   362821 tttttttggt aaaaatgata tttgttcaag aactcgttag gattaataat gccctcttat
   362881 tgttaagcaa gacttgatgt aaaaagtgta tgaataaaca aaatctttta agtcttaatc
   362941 aagatgcgtt gaatgatttc tttgtttgtt tgggtgagaa gcattatcga accaaacaaa
   363001 tcatgcagtg gatttataaa gttcatgagt ttgattttga taaaatgttt aattttagta
   363061 agtctttgag agaagaatta aataaaatag cttgtattga atttcctaag gttgttaaac
   363121 aaaagtttgc cttagataag gtaattaaat gggtgctagc attgagtgaa gacaactata
   363181 ttgaaatggt ttatattcct gaaaaagatc gtggtacgct ttgtatatct tcacaggttg
   363241 gttgtgcttt agcttgtact ttttgctcaa ctggtatgca agggtttaac aaaaatctca
   363301 caacagctga gattattgcc caagtattga ttgccaataa gtatcttaac tctaagacca
   363361 agcgtatttc taatattgtg tttatgggta tgggtgagcc tttgttaaat gagcaagcag
   363421 tgtataacgc ttgtgattta ttacttgatg atttagcgtt tggtttgtct agacgcaagg
   363481 tgactatttc tacttctggt atagtgccat ctatattacg aatgagtaag agaacgccag
   363541 tgagtttagc tatttccttg catgcaccta ataatcaatt acgagataaa ttagtacctg
   363601 ttaatcaaaa atattcgatt gaagaattgt taaaagcttg taaagtatat ttaaacgctg
   363661 gtactcagga gcgtcatatt ttatttgaat atgttatgct taaagatgtt aatgactcta
   363721 ccgagcatgc taataaatta gcaaaattat taaaagctat ctctgctaaa gtaaatttaa
   363781 ttccttttaa ctcttttgaa agaactcaat atcaatcatc aaatgctcag actattgaga
   363841 agtttcaaga tattttatat cagcaaggta ttcgtactat gatgcgtcgc actcgtggtg
   363901 aagatattga tggtgcttgt ggacaattgg ctggaaaagt gctaaataaa accaaaaaac
   363961 ttaatgctag aaagcattga ttactactca aaaaagagta agaaaaagct taaattaaaa
   364021 tgctggttgt tacttatttt agtttctaac gtaggtattt tttggtattt aaatcaaaaa
   364081 gacaatatta aaaaagcaaa agaagtacct gctttaattg ttattaacca tggtgaaaaa
   364141 gaacagaaag aggttgtaag caccgttata atcaatgatt acctattgct taattctggt
   364201 tttaatagaa acattattaa ttcaaaagaa ttagatgaaa taatttataa ttatactaat
   364261 aaacttcaat gaaaccaata catactattc acagaagaga atctaagcaa atatttgtag
   364321 gtaatgttgc tattggtggt gatgctccta tttcagtaca aagtatgact aatactaaaa
   364381 caactgatgt caaggcgaca cttaaacaaa ttagtgaaat tgaagaagca ggtgcagatt
   364441 tagtgcgtgt ttcaattcca actatggaag cagcacgagc atttaaagtt attaaagaac
   364501 aagtcactat ccctttgatt gctgacattc attttgatta taagatcgcc ttagaagttg
   364561 caaaatatgg tgctgattgt ttacgtatta accctggtaa tattggtaga gtagattata
   364621 ttagtgaagt agtagcatcc gctaaagatc atgatattcc tattcgtatt ggcgttaacg
   364681 cgggctcatt agaaaaatac ttacaaaaga aatacacaag gccaacgcct gaagcgatgg
   364741 ttgaatctgc tttgagacat attgatattt tagataaatt aaattttgat aattttaaga
   364801 tttcactcaa ggccagtgaa atttttatga ctgtgtttgc ctaccaacaa ttatcctctc
   364861 aaattgataa tccattacat ttgggtatca cagaagcagg atcattatct tttggtacgg
   364921 ttaagtcttc gattggcttg ggtttattat tgtcaaaagg cattggcgat acgattagag
   364981 tttctttagc ttctgatcca gttgatgaag ttcgtgttgc ttttaatatt ttaaaatctt
   365041 taaatttacg ccaaaaagga gttaatttaa ttgcttgtcc atcctgttct aggcaaaaat
   365101 ttgacgtaat taaagtggtt agtgagttgg agtctcgctt taaagatatt atcacaccaa
   365161 ttgatgtgtc agtaattggt tgtgtggtta atggacctgg tgaagcaaaa tcagtgtcgg
   365221 ttggtttaac gggcggcgat cctaatcttt tgtatcttga tggtaaaact cattccaaaa
   365281 taatcaatga aaatttggta aatgagcttg aagctcaggt taggaatagt cttaaaaacc
   365341 tttaaccctt ttgtaaacct tatagcgata aataaattgt atagcgaagt aaccaaatac
   365401 tgaactagtg atagaaatga ctaaacaacc aagcaaaaaa ggttgccaaa taatatcaaa
   365461 tacctgccaa atatactcta atgacatagc aaagtcttgt tttatattaa cccctaaaag
   365521 ccacgcacca agtttgtaac atacataaaa aatagctggc atagtaatag gattggtaat
   365581 ccaaacgagc gagatagata gcggtaagtt cgcactaaat ataattgaaa ttggtgcggc
   365641 taatagcatt tgaaagggta tgggaataaa agcacaaaat agcccgattg caaatgcttt
   365701 agaaatagac cttctattaa aattccacaa gcttgagtgg tataaacgtt taccaaacca
   365761 atttaagtgc ttatgatttt ttaattcatc tagattagga ctgtaacgtt ttaatagttt
   365821 tttcatgaac gtgcagcatt aagaatacct gcttcattta acccatataa atcatataat
   365881 tctttttgtt caccttgttc actgaattta tctggtaatc ctaagatgct taaagatgta
   365941 tttatatttc tttgatgtaa aagttcacta attgcactac ctgcaccacc tattgcggca
   366001 ttgtcctcaa tagagataag tttgatatgt gaattggcta actcagtaat caaatctttg
   366061 tcaagtggct taacaaagcg catatcaact acagttgcat ttagcttctt gcctgcacta
   366121 aacgcgcttt caacagttgt accaaaagca aagattgcta catcagagcc tttaagtata
   366181 attttagctt tacctaatga aatttgttta tcagttacat aatcttggat atttgacaca
   366241 cctctagggt aacgtatgca aatagtgtta ttagttttga atgcagtatt gaacatttga
   366301 tacatttgca ttgcattgct tggcgtcata atgattaaat tagggataca tcttaagaaa
   366361 ctcaaatcaa aactacctgc atgagttgcg ccatcagcac ctactaatcc agctcgatca
   366421 attgcaaaga taacatttaa attctgtagt gcaatatcgt gaattagttg atcataacca
   366481 cgttgtaaaa aagtagaata aatagctact attggtttta atccttgcat agcaagccct
   366541 cctgcaaaag taatagcgtg ctgttctgca attcctacat caaaatattg cttgggataa
   366601 tttttttcaa attcgctcat tccagatcca gcgcacatgg cgggcgtaat agcaactaag
   366661 tttttatgat gaagtgctgt attatttagc caagtaccaa atacagtact ataactagga
   366721 aaactagagg tatttgatga ggcaggtgtt acaccatgaa atttacatgg atcattttct
   366781 gctatcttaa gtccgtaacc ttttttagta ataatatgca agagtctggg ttttgtttgt
   366841 ttttttagat tttttagagt ctggatcaaa gtaggcaagt catgtccatc gataggtcca
   366901 aaataatcaa gtcctaactc ttcaaataaa gtactaggca gaaccatacc tttaaggtgc
   366961 tcttctgagc gtttagcaaa tttatgtatt tgaggaattt tttctaaaaa tcctaatgat
   367021 tttgatttca ttgttgaata aaccttacca gagataagcc tagtaaggta tttattcatg
   367081 gcaccaacat tttttgatat tgacatatca ttgtcattta gaataataag taagtctgca
   367141 tcgctatcac ctgcatgatt aagagcttca aatgacatac cacctgttag tgcaccatct
   367201 ccaattacag caatagattt acctttgctg ttattaatac tattaccaat agcaatgcct
   367261 aaagcggcac taattgaggt tgatgaatga ccagcgccaa aactatcatg ttcactttca
   367321 ctgtgttttg tgaaaccaga taacccacct ttttgacgta atgtatgcat tttatcgaaa
   367381 cgacctgtga ggattttatg ggtataagcc tgatgtccaa catcaaagac aagactatca
   367441 taaggagtgt caaatatata atgtatagca atagtcattt caattatgcc aaggttggga
   367501 gctaggtgac cacctgttct ttggatgttt tcaattaaaa atgtacgtac ttttttagct
   367561 aaagactgta attgtacaat attaagttgt ttaatatctg taggcgatgt tattgaattt
   367621 aacactaaaa taaaggttca acttaaaaaa gatattatat acttgtaata gtaaggttat
   367681 tttaaaacta ccaagaagga cggcgaattt ttagagaatg gtctttttta atgtttttgt
   367741 ttttaatttt aattttttca ttaaaatttt tagcgataaa gccaagttct ggtttgattt
   367801 ctcgcatcgg aatccacact tgataaccac taccttttgc aacatccaac ttttcgttat
   367861 gcttggttag tatatattca attgtggtat taaaacagcg atcaggtagg ataacctcaa
   367921 tagaatttcc aacgctaaat ttgtttttaa ctttaataaa agctttccca tctttataat
   367981 ctaggatctc ccctaccact tgttgtttgt ttgaacgtga ataattctca aaataagttt
   368041 gtaattcttc cggttgatgt ctttgataaa atccatcggt gtaacctcga ttagcaaggt
   368101 tttctagtat accaaatgcg tctttattaa attcacgtcc agcaacagca tcatcaatag
   368161 cttgccgata cacttgtgtt gtacgtgcaa cgtagtaatg tgatttagtt ctaccttcta
   368221 ttttaagtga attaatgcct atagttgtga gtgtgtgcac atgttcaata gcgcgtaaat
   368281 ctttggaatt catgatataa gtgccgtgtt catcctcgaa agtgggcatt aattcaccaa
   368341 gtcgagtttg ttcttcaagt aatacaactt gattttcagg agttttgatt ttaactgctt
   368401 taacatcacc tttaaaagtt tccttagctt ttttaacgtc atatttccag cgacaagaat
   368461 tagtacacga accttggttt gggtcgcgat gattaaaata tcctgacaat aaacaacgac
   368521 cagaataggc aatacacaat gaaccatgta caaatacttc tagttcaacg tctgggcatt
   368581 cttggcgaat atcttttatt tcatctaatg ataactcgcg tgaaagaata atacgactaa
   368641 cgcctgtatt tttccaaaat tttaccgttg cgtagttaat tgaatttgct tgaactgata
   368701 gatgaataac ttgatttgga aatttttctt ttaccatcat aattaaacca gggtctgcca
   368761 taattaaggc gtcaggacca agattaataa taggttcaat atcttttata tacgttttaa
   368821 tcttgctatt atgtggaatg atgtttgagg caataaagaa ttttttatta tttgcatgtg
   368881 cttcaagtat gccttgcttt aaggttttag tatcaaataa gttgttacgt actctaagac
   368941 tgtatcttgg ttgtcctgca tagacagcat ctgcaccata agcataagca taacgcatgt
   369001 gtttaagact accagcaggg gaaagtaatt ctggtctatt catacgttca ttttatcatt
   369061 aacagtttat taaataccct tattgtataa taaggggtga tatgtttaca aaaaaagata
   369121 ttccaaggtt aaagcaagat ttaactattg aaacaaattt acttggagtt aacttaactc
   369181 taaaaacacg ttggggcgta tttagtcctc gttctattga tgacggtact aaattattca
   369241 tgaagtattt gaagattatt aatgatgaca agtgtcttga tttaggctgt ggttatggtc
   369301 ctattggttt agcagttgct aagtcttgtc caaaaacaga ggtgcatatg gtggataaag
   369361 attttattgc tgttgaatta tcaaacatca atgctaaact taatcgtatt gataatatac
   369421 aggtttattt atcagatgca tttttaagtg ttaacaaaac agactatttt gatcaagtat
   369481 tgtcaaatgt gcctgctaaa gtaggaagag aacagctaag tattattcta tatgatgctt
   369541 atgatgtgtt aaaaccaggc ggtaaaataa catttgtatc cattaatagc ctaagacatt
   369601 ttattaaaaa taattttaaa tttgtatttg gcaattataa aaaactcaaa cagggacaaa
   369661 agtatacagt ttctcaggca attaaataga aaatatttgt aaaaaaataa tatatgagta
   369721 aaatactcag tatttaaaca tgaaatagga gtaatagaat ggatgtaatg gatagaattc
   369781 aacatcaagt agatagcgca gcagttgtac tttatatgaa aggtactcca caatttcctc
   369841 agtgcggatt ttctgctaaa gcagcacaaa cacttacttc aacaggtgtt gagtttgcct
   369901 atgtgaatat ttttgaagat caagaggtat ttcaaagttt gccaactttt gcaaattggc
   369961 caactttccc tcaaatttat tttaattcag aattagttgg gggtggagat attattgtcg
   370021 aaatggctga aatgggcacc ttaaaagatg agatgaaaaa agcctctgaa aagtttgatg
   370081 ttaaatgatg tgtttacatg tgttagtata attataatag tcaaacttta tcttgcctta
   370141 ttaaataccc caatttgtat taatcaaccc aagctctagc gttttcaaac attcttatcc
   370201 acgggccacg ttcacgccaa tattttggat gataagagtt ttgtacgctt ctaataacac
   370261 gctctgggtg tggcatcata atagtgactt gcccagattt atttgtaacg cctgctgtag
   370321 caaaatccga accatttgga ttatgtggat aattttgtgt tggtttgcca tcatggtcaa
   370381 catattgcat aattgaatag tttttattca tttgaagtgc aaagcttgca cgaccttcgc
   370441 cgtgagcaat gctaattggt ataattgagc cttccatttc tttgaagaaa attgagtttg
   370501 atggtttgat ttgaaccgag gaaaaacgtg cttcaaattg ttcagaagtg ttacgcttaa
   370561 aagttgggaa atgttcacta tcaggtataa tctgtgttaa attagacatc atttgacagc
   370621 cgttacaaac accgagtgca aaactatcat ttcgattgaa aaaagcttca aattcgtctt
   370681 tagcacgttc attatacaga atagaacctg cccaaccgcg tcctgcacca agcacatcgc
   370741 cataggaaaa accaccacaa gctactaatc ctttaaaatc aactagagag acttttccag
   370801 ataaaatgtc attcatgtgt acatcaatcg cactgaattg tgctttggta aatgctacac
   370861 ccatttcaat ttgaccatga atgccttgtt ctcttaaaat ggcaattttt ggctttgttg
   370921 gtattttgat ataaggtgct gatatggatt tgttaatatt aaaatttaaa tcaattttaa
   370981 ttcctgatgt gcgttcacta atactgctaa attcttcttt agcacaattt ggattgtctc
   371041 ttaatttagc aattttataa gaagttgatg accaaagttc ttgtaattca gctcttggtt
   371101 tgttgtaaat taaattatca tttgaactaa ttttgatcat gtcagtattg ttaattaaag
   371161 caatggtgcg tgtgaaatta gagagtccta ttttatcaag agccttcatc actgtttgtt
   371221 tgttcttatt tttaacttga atgacacaac ctaactcttc attaaataac tcttcaattt
   371281 caccattaaa attgatatct agaccacaat gtgaggcaaa tgctatctct aataaagtta
   371341 caattacacc accatcacta cgatcatgat aagcactaat tagaccattc ttattaaatt
   371401 ggttaatgac agtgaagaat tttttaaatg tagtttcttt gtcgagatta ggtgcaatat
   371461 ttcctatttg gttataaacc tgtgcgatac atgatccacc cattctattt tgaccaaagc
   371521 ctaagtcaat aagcaataat tcactttctt gtgtgttttc aagtagtggt gtgagttgca
   371581 accttacatc ggatgtttta gaaaaggcgg taatgataag agagagtggt gcggtgactg
   371641 atttgtttat atcattatct ttccatgtgc ttttcatgtt cattgaatct tttccaactg
   371701 gtatagttaa gcctaattta ggacataatt ccatgcctac ggctttcact gcttgaaaaa
   371761 gcttaacgtc ttcattttca tgtccgcttg cactcatcca gtttgcacta aggttgatat
   371821 gttgaatatc ttcaacataa ccaccaagca tattagtgag tgcttctcca attgtcattc
   371881 tagctgcgca gcgtgcgtca caaagcgcta aaggtgcacg ttctccaagt gacataattt
   371941 cgccattaaa accaacgtag tctgcaattg aaattgcaca atcagaaact ggaacttgcc
   372001 atggaccaat aaattgatca cgagcaacca taccagtaac gcttctatcg ccaattgtga
   372061 ttaagaaatt tttactcgcg acgcttggca gttgtacaat tctagtgatt gcatcatcta
   372121 gtttaatatt gctagtatct aaaatattga gtatattagt agatgatttg gcattaatac
   372181 tagttttagg tgggttacct aataaaacag tcattggtat attaatagga atattgttaa
   372241 ataatttatc atttagaact aatatttgtt ctttagttgt ttcgccaagt acagcaaatg
   372301 gcgagcgctc acgtttgcaa atatctgtaa atacgtttaa gtttttttca ctaatagcaa
   372361 gtacgtagcg ttcttgtgat tcgttacacc aaatttcaag tggtgacatt tggttatcat
   372421 catttggaat ggcacgtaat tgaaattttc cgcctctgct agaatcattg attaattcag
   372481 gtaagccatt tgataaaccc cctgcaccaa tatcatgaat agaaataatt gggttgtttt
   372541 cttctagatt ggtacattga tcaataactt cttgggcacg tctttgcatt tcaggattgg
   372601 cacgttgtac tgaggcaaag tttaggtctt cattttgttt gtcactttta atacttgatg
   372661 ctacgctacc tcctaaccca attagcattg aaggcccgcc taaaacaata attttacttc
   372721 caactggaat attacctttt ttaatatgtc ttcgttgaat atgtcccaat ccaccagcaa
   372781 gcataatagg cttatgataa cctcttatat ctccattagg catttgttgt tcaaaagttc
   372841 taaaatatcc taatatattt ggcctaccaa attcattatt aaaactcgct accccaatgg
   372901 gagcttctag aataatatca agggctgatt gaatttgatt tggctttcca tgttcaattt
   372961 cccatggctg tttagcattt ttaattttaa gattagatac actaaaacca cataacccga
   373021 ctttaggttt tgaaccctga cccgttgaac cttcatcacg aatttcacca ccagagccag
   373081 ttgcagcacc ttgatacgga gcaatagcag tagggtggtt atgcgtttca actttcatta
   373141 aaattgcacg gtgttcttga gtgcttacat attcattatt ttcatttgcg taaaaacgct
   373201 caccttgata accttccatc actgctgaat tgtctgaata aacgcttaac aaaccttttg
   373261 ggttctgatg ataagtgttt cgaatcatag aaaataaact tttttcttga gctatatcat
   373321 caattatcca atcagcatta aatattttat gtcggcaatg ttctgagttt atttgtgtga
   373381 acatcattag ttcaatatca tttggatttc gtttaaggtg tgtgaaattc tcattcagat
   373441 agctaatttc actatcagat aaagacaagt tcaactcaat attgctacgc tctaatgcag
   373501 actttcctcc atttagaata tcaatactag atagtgattt tgctttaagt ttattaaaga
   373561 ttaaatacat attatcaatt gagtcaagct ctgattctgt catcttatcc ataattattg
   373621 ctagaatatc agctttatta tctgatatct tgtcaaaatg ataaattatc ccccgttcaa
   373681 tgcgacgtat tttttcaagt ccacacaagt gtaaaatatt acttactttt gacgaccaag
   373741 gtgagattgt gccaagacgt ggtatgataa taatttgtac actgttattt attttaatat
   373801 gcgcttcata acttaataat ttttcaagtg taagcaattt actactgcta agtgtattct
   373861 cacaatcggc aaaatgtata tattctatac caattagatt taccccaagg aaagctattt
   373921 tcttattgag tgtatctttt ttgaaagtgc ttagagcttg aatgtgttga atggttttaa
   373981 tcataattaa ttcttaattt ttgtaacttt tagttctttg taagtttatt ttgatatcgt
   374041 ttgacatagt ttgtagtttt ttatctaaat atctttattg ttagatatgg ataatttgtt
   374101 tttatattgt acaaatcgtt ttagaattgt gttattattt catcagaaat atccgcgttg
   374161 tgatatacct ctcgagtgtc gtctaaatct tttagactat cagttagttt tatgaatttt
   374221 tctgtattat gtagattaag tttaatataa ttaataggtt tcattgttac ttcagagtga
   374281 cttggttcca atcttgctgt gatgagtgta tttctaatgg tgaaaaaatc ttcagttgta
   374341 gtgatgacat aaatagaacc attatcattg gtgataatat cttttgcacc tgcatcaagt
   374401 gcgacttcca tgatttgttc ttcatcgcct gtctcaaaat tgataaatcc ttgtttgata
   374461 aatagataag atactgaacc ttctatgctt aaattacctc cgtattttga aaaagcatga
   374521 cgtatatttg caactgttcg attgcgatta tctgttagcg tatcaactat aatggcagta
   374581 ccagctaaac cataaccttc gtaacgcact tcatcatagt ttttgtcatc taaatcgcaa
   374641 ctaccacgtt taactgcatt ttcgattgta ttgcgtttca tgttggctgc taaggctcta
   374701 tcaattacca ttctaaggga aggattattt tcaatcacac tcccacctgt tttagtagcg
   374761 atgataattt ctttaatgaa tttggcgaat atttttccac gtttaacatc ttgtatgccc
   374821 tttctatgtt gaatattatg ccatttacta tgtcctgcca ttaaattttc tccagtttgg
   374881 aattttatct tatatagtaa aattaagtaa tttgtgtatt gatttttttg cttgaattac
   374941 gattgattga tcaattatta tctcatgtgt tttgttttga atagcatcaa ggcaattatc
   375001 tagggtattc attgccatcc attgacaatg tgcgcatgat tcacaatctg cactttcgcc
   375061 catagtaggc gcttctatta gtttcttatt cggtgcaact tcatgcattt tatggaaaat
   375121 gccattgtca gttgcgacaa taaaagtttg ttcttttcta tttttgactg cattaattag
   375181 tgttgtagtt gagccgatta catctgctaa atccaccact tcttgtggtg attctggatg
   375241 aactaatgtt gcggcttctg gatatatatt ttgtaattga atgagcgctt tagctttgaa
   375301 acgctcatgt accaaacaag cgccttgcca aagtagcatg tcaacacctg ttttattttt
   375361 gacataatta cctaaatgct tatcaggcgc ccataagatt tttttgcctt tatctttaag
   375421 gtatttgaca acgttaagcg cactacctga ggtaactacc caatcagctt ttgctttgac
   375481 ttgtgccgag gtgttagcgt agacaacaac tgttctatta gaatgttcat cgcaaaattt
   375541 ggaaaattcg tcaattgggc aatcttcatc tagcgaacaa gtggcgttgt catctaaaat
   375601 gagtactgtt ttttcaggag aaaggatttt agcagtttct cccataaatt taacgcctgc
   375661 aacgataatg atatctgcat cacagttttg gctaaaacgt gccatttcta atgaatcaga
   375721 aacgatgccg ccagtttctt ctgctaaggt ttgcaatttg gcatctacat agtagtgtgc
   375781 aactaagatt gcattatgag cttttaatgc tgttttaatt ttttcttgaa ttgacaacac
   375841 ggatgattag tttttttttg gcaggctaat tttaacattt aattcgcgca ataatttttt
   375901 tggtacgttt gcaggtgcat cggttagtaa gcatgtggca gtttgagttt taggaaaagc
   375961 aattacatca cgaatgttat ctgtacctgt cataatcatt actaagcggt caaggccaaa
   376021 tgccataccg ccatgaggtg ggcaaccgta ttctagtgca tctagtaaaa atccaaactt
   376081 atcttgcgct tcttggttgg aaatacctaa taattttaac actgtttttt gcatctcaac
   376141 ttggtgaata cggatagagc caccgcctat ttcggagcca ttaataacca aatcataagc
   376201 acgagaaaag gcggttttag cagtttgttt taatgtttct ttgtcaacta taggtgcggt
   376261 aaatggatga tgggtagcat ttaatgagcc attatcattt attccaaaca ttggaaaatc
   376321 aactacccaa ataggcgccc attgtgtatc aaataaattt aaatctttag caattttctc
   376381 acgtaaattg cccaaagatt cattaacaat tttggtttta tcagcaccaa agaaaataat
   376441 atctcctgtt tttgcacctg ttatttctat gattttatta gtaatttcat catctaagaa
   376501 ttttaaaatg ggagaagttg gaccattttt attaagtttg atataagcta agccttttgc
   376561 accataaatg ccaacgtatt tagtatattt atcaatattt ttacggctaa tactagcacc
   376621 acctgatatt tttaaagcag caacacgaga attactatta ttagcaggtt ttgaaaatac
   376681 tttaaaatca acatttttca ttagtttatc tatacttatt atttgtatgg ggatgcgtat
   376741 atctgggcag tccagtccgt atttttccat ggcatcttca taggtaatag tagggaattt
   376801 attgcctaag tcaacattaa taactgattt aaataagcct ctagtcattc tttccattat
   376861 tgtcatgatt tcattttcat tcataaatga tgtttcaata tctagttgag tgaattcagg
   376921 ctggcgatca gcacgtaaat cttcatctct aaaacattta acaatttgat aataacgctc
   376981 aaatcctgac atcattaaga gttgtttaaa taattggggt gattgtggca aggcaaagaa
   377041 cttgcctgga tgagtgcgtg aaggtactaa ataatcacga gcaccttctg gagtggcttt
   377101 ggttaaaaaa ggggtctcaa tgtctaaaaa atcatgttta tccataaatt tacgaatgta
   377161 atgagtaaca cgagaacgta agtgtaagcg tttttgcata gcattattac gtaaatctaa
   377221 atatctatat cttagtcgta tttcttccga ggtgttgatt gcattaattt ggaatggtgt
   377281 tggtttagaa gtattaagaa tttcaatatt ttgtgcttta atctcaattt caccactgac
   377341 cagtttagga ttacttaacc ccttgtctct ggcgataact agacctgaaa tttttaatac
   377401 aaattcatta cgaatagtct cagccaaaga aaaatcttta ttatcaggat taataactac
   377461 ttgaacaata cctcgtatgt ctcgtatgtc taaaaagata acaccgccat ggtttcgttt
   377521 gcgattgacc cagccataaa tttctattat ctgtcctaca tcagatgtgt ttatcttacc
   377581 acaataatgc gtccttatca ttttatttgt ccttctttta ttggtgttat cactccagta
   377641 gaaataacca gtttaaatgc ttcatcaaca ctcatgtcaa gttcaattac atcatttttt
   377701 gctagcataa taaaaaagcc agaagtaggg ttgggggtag tgggtacgta aatattaatc
   377761 acttcttttc caattttttt tgctacttca ccgctatagt tgcttgtttg aaaggcgata
   377821 gtccacatac ctttacgtgg atattcaact aatactgctt ctttgaagct tttaccagaa
   377881 gggctaagta ccgtatccga aagttgttta agtgcactat agatgcttct aaaacctgga
   377941 attttattga gtaatttttc ccaaagttgg attagtttac gaccaataaa attattaact
   378001 aacgcacctg ttatcaacag gattaaaata acccaaataa tgccagatcc aggaatggtt
   378061 ccgtttaaat taaataaagc ttctggcagg tattgaaaag ggacaatatt attaattagt
   378121 tctaagaaga atttaataac aacaatactt aagcctaatg gtatccaaaa caatagacca
   378181 gagataaaat aatttcgtaa gcgtttcaat gatttaaaat aatagcaata aagaatgcta
   378241 ttttagcata gtcattatat tatttttata ctggctcttc atcatctctg agtgttaaaa
   378301 tttcgcatcc attttctgta actaaaatag tatgttccca ttgtgcagaa agtgtgtgat
   378361 cttttgtggt tactgtccag ttgtcgattt tggaggtgat gacttcaaac ccccctaaat
   378421 taatcatagg ttcaattgta aatgtcatac ctgctttaag gattggactg atatttaatc
   378481 ttccgtcatc ataatgaatt acttgaggct cagcatggaa ctcagttcca ataccatgtc
   378541 cacaataatc acgcactacg gcgcaattat ttttgtttgc atgagcgcca attgttttgc
   378601 caatttcacc taaatgaact ccaggtttta cttgtttaat accgatatat aaacattctt
   378661 gtgcaatttt gcaaatacgt tgtgctttga cactagattt accaatgatg aacatttttg
   378721 atgtatcacc atgaaaacca tttttaataa tagtaatatc aatattaata atatcacctg
   378781 ttctaagttt tctgtttcca ggaataccgt ggcaaactac atggttaata ctagtacaaa
   378841 tagattttgg aaagccgtga taattaagag gagcagcgat agctccttgt tgattaacaa
   378901 tgtaattatg acaaattttg tctaattcat tggtactaat gccagcccta acatagggtg
   378961 atatcatatc aataacattg gctgctaaac gtccagccat acgcatcttt cctatttcgt
   379021 tttttgattt gattgttatt gacatgagac tttattttga attcttttaa tacgtttatc
   379081 tagtggtgga tgagtggcga ataatttact acccatacta aatagcatgg catgggcata
   379141 ttctttggca ttaggattct taagtgtggt tgtagcatca ccttttatga tttcaaatgc
   379201 ctccaccaaa ccgttaggat aacgagtaaa ttggatagca gatgcatcag ctaagtattc
   379261 gcgttggcgt gacattgctg cttgcaagat acgtccaaac caaactgtca tcattccaat
   379321 taacgcaata atagcagcgg ttgccagtaa taacaatttt acacgaccat ctatacgacg
   379381 attataagcg gcttggtaaa atatcactct agagagaaaa aatagcacag taaagctaaa
   379441 cacaaatgca ctaatttgta tattaagctt aatatcatgg ttaacaatat gcccaatttc
   379501 atgagcaatt atgccagata attgagtacg attaaaactt ttcattgagc cttgggtaat
   379561 agcaataatt gcttcttgag tagtttttcc tgcagcaaag gcgttaatag cattatctgg
   379621 aataatgtat aaggtaggag taggaatgtt agctgctaag gcttgctcag caacgatatt
   379681 aagcgcttgt ttttcttcaa ttgacagttc gttgttttta tcactaatta atttaccatc
   379741 aaaagaaagt gcaactttat gtccatttga tttttgaaaa aaaccaaatg ctgtagcact
   379801 tatcattgct aataatacca ttaatgaaaa tcttaaaaaa ttgagtaatt gttcttgatt
   379861 ttgaaagacg atttgattag cggcaatgaa cttttcacta agactgtatt gttgatattc
   379921 aggctgataa aactgtgcta aatttagtcc aacaaacaaa gtataagata ttaatataga
   379981 tgagattagt aataaaacaa ggtataaaga ccaaatgatt agagtgtttt ttttagcctt
   380041 gtcttgatgt ttcctaaaat ccattgttaa gagatcctcc agaaatcata gcgtgattta
   380101 ggaactaaat tcttttcagt acctttttga gggataggaa aaagtttagt tttatatatt
   380161 ttagtacgaa ctcctgccat tggatataaa taatatttct gtccttaaga aaataagttt
   380221 ttaggtgctt gctttaattg ttctatgctt tcgttaaatt ctaagttttg tgcatctaca
   380281 ctaaatccaa atatactggt aaataatata tttggaaatg attttttgta ctcattaaac
   380341 ttttgaacca agtcgttata cccttgtcta gcactagcaa tgcgattttc tgttgcgatt
   380401 atttcttcgc ttagttgtat catattattg tttgctttta aatcagggta ggcttccatt
   380461 tttaagttaa aaccattcat tgcactttcc agagctactt gagagcttgc taaatttgtc
   380521 atagcatttg ttttatctgg atttttttgt gccaccttat tagcttgtat taattctttt
   380581 ctagcttcag taacagtagt caacgtttct ttttcatgtt tcatgtattt tttggcaata
   380641 tcaactaaat taccaattaa gtctaaacgt cgtttaagtt gtactgaaat ttgttcaaaa
   380701 ccattctgat actgagtttt ataagaaacc aggttgttat aaatactagt aatccaaata
   380761 attaaaacaa taataattgt aaccagtaac cagttttgta ttaaaaattc catttttaaa
   380821 ctcctataaa aagttaatca atattaattt ttaaaatgtt gattatatac ggtattatca
   380881 tttaaattca aatcttgaat ccaattttca tttatttttg aatattttac atttaattaa
   380941 gtaatgataa aattaagtgg agctcgatta aatttgtaaa tctttagcat gtactttttc
   381001 aattttgtta agatcctatc accaatgatt ggataaccat aaccacttaa atgttttttt
   381061 gttatctatt ttttatttac ttatagtgat gattaagttt attttttaca aacttgttat
   381121 ctagtgtgat tgttctattt ggaaactttt ttaataattt tagtgagtaa cactcgttaa
   381181 ctcattggtt ttatttgtta aacctttata ctcaagaact ataacaattt aaagattttt
   381241 agccaacctt ctaaatacat actggttttt ctattttagg ttttagaaaa ataccctggt
   381301 tagttaaatt aaatactata ttttttgttt aataataatt catctagttg tttctattta
   381361 agataaataa aaacttcttg ctaatttttg agtagttttt taatagttct ttcctttctc
   381421 agttattttt accgattgta agtcgcttat aacttttata tagttctgat tttagtattt
   381481 gttttgataa atcataggag tttattgtta aagtattaaa taataattaa ttattatttt
   381541 tttgaaaaaa cacaaattaa aaatataaat cctaatagga tggggcgaga aacgggattt
   381601 gaacccgcga caaccggaat cacaatccgg ggctctacca actgagctat tcccgccata
   381661 aattattact tcaaggggtg gtacgcccaa cacgatttga acgtgtgacc tacggcttag
   381721 aaggccgttg ctctatccag ctgagctatg gacgcgcata taccaaggtt gttgtaaaac
   381781 gttctatcaa tgcaaggtat ttttttggtc ggagtggagg gatttgaacc cccgaccacc
   381841 tggtcccaaa ccagatacgc taccaaactg cgctacactc cgaaaaaaat aatgattata
   381901 ctttgttaaa ttggaatata aatagttaaa tagtgattgt gttataatta gtaaattcat
   381961 atttaatatt aacatattat caattttttt gtatggtttt ttgtctattt taattaggtc
   382021 ctccaattca tgattggttt gcttcagtaa gactatatta gtggtactaa ttcctatttt
   382081 taagtcaaga tcataaatta acgaagaaaa gtaaggacaa ttaattgacg tattattaat
   382141 caaagtagtg ttatagttta gaccaacgta cgtgctcaat atacaaatcg ttttttccaa
   382201 tttttagtgt aaaaatcatc aataattata aacttggtat aattactatt ctgatatgag
   382261 aaagtttcaa tcttttagat agaaatctat tataagtaga gtaataaata tctaaattct
   382321 atcgtttaaa gttctttact gattgttatc actgagtaaa tagtgttgta gtatctttca
   382381 atcaacaggc ttgaaggaat aatctatctt tttagataat tcttgtttag tataaacttt
   382441 tagtggaatg tgattgagtt agttttattt tctaacttga cgataaacct aataattgtc
   382501 ttaaattaat taaagttttt taaagtaatc tgcatgcgct gcgagttctt ttttatttgc
   382561 ataaacaatt ttgattttgc caatagcatt gtttatcctg acaatattat tagtattatt
   382621 gtcttgttca ttaatggttt tatcattgct aaataaagta gattgtccgc cagtcattgc
   382681 aagataaact tgtgctagaa tttgtacatc taacagcgca ccatgcacag ttcttgcact
   382741 tgagtcaatt ttaaatcgcc gacataaaga gtcaaggtta tgtagtgttc caggtcgttg
   382801 ttgtttagac aattctaatg aatcaataat ggtacattta tcttcaatgc gttcattaat
   382861 acctataagt ttaagttcat ggttcagaaa tccaaggtca aatggggcat tatggataat
   382921 gagagttgtt tctttaatat aagctaaaaa ttcttcaaca acttctttaa atttaggctt
   382981 ttttgttaaa aatttatcag taatgccatg gatgcgtact gagtcaccaa cattacgatt
   383041 tggttgtatg tattcatgat atttattatt tttagtgatt tgtctatcta taatttctat
   383101 acaaccaatt tcaattatac gatgaccttc agaaggctta atccccgtag tttcagtatc
   383161 tagtacaatt agtctttcca tcgaatattt cttaaactta tttttcgtgt acaattatct
   383221 cattttatca taagtaatat tttaaatatt atggcaagag taacagtcga agattgttta
   383281 gaccatgtag aaaatcgctt cgagttggta ttgatagcag caaagcgtgc acatcaatta
   383341 agttctggag gttataaacc attattaaat gcgggtaaag ataagccaac ggtagtagcg
   383401 ttaagagaaa ttgaggcagg attgattgac tcttcaattt taagtgaaat ttatgtaata
   383461 gatgagcaat tatcagcaca acaaaaagta ttggatagtg taaaaatgtc tgaaattaaa
   383521 gatgaattat cagtaacagc tgttgataaa gttattgacg agataacaga aattgaagag
   383581 tagataatat ttaattcatg atgtgatata tgtcattatt tattaaaaat ttatttgtta
   383641 ctttagttat ttatcatcct aaatagaaca ttttattatt ttatgtattc caatataaag
   383701 ttggctattc ttatacattt ctatcttgtt tttagaagat atgggttcga actagttctt
   383761 agagactgaa cctaatgttt ttggtataac tatagtgatt aactttgcag ttactttctt
   383821 aataatgact ctcacagtgt caatacctaa atatgttgtt aatttatttt gataacttga
   383881 aaataataat gttagatact ttagaaatta aaacatagaa aatgcactat taattaggtc
   383941 ttatgttaat gctgatagtt cagaattgtt ttttaaaaaa tataatttgc ttcattataa
   384001 aatatgcttg tatgcagttt ttacttctta aattatctgt tatttatcta atcagtagac
   384061 ctagcaaatc atctatatat gatgaagtaa cttatcaaaa ttcaattgat gataataatt
   384121 tatttttggc atagtaagca agagaatttc tagattgtaa aaaagatttg aactaaattc
   384181 tctaatgcta attatataaa atcctaattt gatgggttta aagagagtga gttaaatatt
   384241 atttataatt atattgataa acatttatca atacgtgcaa attaaatagc tgtcattctt
   384301 ggaaggtgat gggcttaagt taagttaata tttacttgtc aacatcttca tgacgaggcg
   384361 gtaaaactta gcaatggctt taaaacttta agaggtgaga aaggcgatcg attttacatt
   384421 tatattttga taatttcaca agtaagttat gctatattag cttgtgtttg tattagtagt
   384481 gttcattcta tggtatttga ttgcttctca ttagaagcat taaaaaatag aattttagac
   384541 tcttaatgta agatgttatt actgacaata aagatacacg tagtggtaga actaccatgt
   384601 taaaggtaaa ttttgattaa acagttattg ggtgtgattg tattgataaa atgattgtgg
   384661 tgaaaatata aaagtaatgt taattaatag ttttaatact gcatcgataa tcatccgtac
   384721 attaatgggg tactagtggt taacatgtta ttaacacctc atgtttgagt tacgtatttt
   384781 gtgtataact ggttaatccg ttaattctta agcatggaag tgatattatc attctattag
   384841 gaaaagcaag tatcctatgt taatacttgg cggtaagcat aaataggtag tcatatgatt
   384901 aagcttttgg ctaggacaaa tgtgtacttt gtacaaatga ttatcaatgt tttataaaga
   384961 tttatttttc catatctagg taaataattt ttaagtgata gggcatatta agcttgatgc
   385021 tgatggttgt tattggatta ttaggcgtgt agatgatgaa tgtagttaat atttctggag
   385081 attgtttagg tgtggcagaa attgaatcta cactgatttt acataataat gtttcaagag
   385141 gatgaagtag tggattatcc ttatgatatt aaaaattatt atcttgcagg cgttaataat
   385201 gaccaatatt tatataacga gtttgtttaa aactgaattg gttaagttag tgtgatccgt
   385261 gaaattagat ctattattac tatagataaa attcaatttg taccaggggt tactaaaaac
   385321 tcgtagggtg agattatgcg taggatttta agaaaaattt cacaaaataa ttatgataat
   385381 ttaggctata cttcaacttt agaaaagcta aaataagctt tttttcttat ttgctagtta
   385441 taacttttct ttgaaacttt attttcttaa gcattgttga agataattta ttcgcatatt
   385501 cttatttaac gatataacct tgccaaatac cttgtattct aagttcatgg tatttttaat
   385561 attattgcag taattctgta tttcttcaga agtgtaagag attaaggtgg caataccaat
   385621 agcaggtaca ataagtcctg ttacaacaat acttgttgat gcttctttta attttttaat
   385681 atgggcaatg ttttttgtga ttatgttttt gttttgttct tcaaaaatac cttctaagta
   385741 tttaagcttt tcatcagagg tttgtaattt tttttgaatt gaagttaata aatattttaa
   385801 gtctattatc tctattcgag cattatttat ttgtaaaatt tcatcattta aaacatgacc
   385861 tttgctagtt tctaatgaaa gtttatcttg tgcttttttt aattctgaat gtgttttgat
   385921 taattgttta ttgaggttct ctagcgtatc gctattcctt atggtaacag gaaattttgc
   385981 aatttgttta acgttgtatt cttgtttaag gttgctgatt ttattgttaa gttgaataac
   386041 ttgattattg tggataaaat aaccaataat taaagttatt attagagcga ttgagctgaa
   386101 taatgattta ttttccataa taatttctca aaaaattaat aattttgatg taagtattat
   386161 tacatcagcc acttagcaac ttgtttagca taataggtta aaataccatc agcaccagca
   386221 cgtttgaatg ccaataaagt ttctaatacc acttgttctt cctttagcca gttgttttgt
   386281 acagctgctt ttaacatagc atattcgcca ctgacgtgat aagcaaagat aggaatgtta
   386341 aaattttgct taattcgata aacaatatcc aagtatggta atccaggttt aatcatgatt
   386401 atatctgcac cttcatcaat atctagagct acctcacgaa tagcttcatt agagttagct
   386461 ggatccattt ggtaggtttt cttgttagat tcacctaaat tagctgagga atcaattgca
   386521 tctctaaatg gatcatagta gtgagaagca tactttgcag aataagctaa aatatttgtg
   386581 tgaataaatc catttttttc aagcgcttta cgaatagctc ctatacgccc atccatcatg
   386641 tcgcttggcg ctacaatatc agtaccagct tgtgcatggg aaagagcttg tctaactaaa
   386701 acttcatttg tttcatcgtt gagtacataa ccattattat caattaatcc atcttgaccg
   386761 tgtgtggtaa atgaatcaag tgctacatcg gtaataactg ctaagtttga atatttttgt
   386821 ttaacagtgt atatggcacg ttgtattaaa ccgtctggat taaatgcctc tttagcatct
   386881 aatgattttt tgataggcgg aacaacaggg aaaagtgcaa ttgcctgaat acctaattca
   386941 attaattcag ctacttcaat taataattga tcaacactca aacgtttaat acctggcatt
   387001 gagttaatat tttgtcgttt attttcacct ttaatgataa aaattggaaa tattaaatca
   387061 ctagttaata agtgattttc acgcattaat tcacgagtat atgagtgttt tctcatacgg
   387121 cgtggcctat gggttaaaat tgtcatatat ttatatattt atatatttac ctttggtata
   387181 ttatacttca atgaatcaat caaactcaac tttcaaaaat atgtcaaatg ttaatgaagc
   387241 gttaatcaaa ccattcccca attctaataa aatttatgta caggggtcac gtaaagatat
   387301 tcaggtgcct atgcgtgaaa ttacacttac agatacaatt ggtgaattgg cagaaaaaaa
   387361 tgcgcctatt cacgtttatg atacgtcggg tgtttatacc gactctaatg ttaatattga
   387421 tttgcgaaaa ggtcttggga atattagagt ttcttggatt aaagagcgaa atgatactga
   387481 aatattaacc gaatttagtt ccaatttttc taatgaacgc cgagatgatg tgcagttaaa
   387541 tgcattacgt tttgaacatc tacaagtacc acgtcgtgct aaagatacta aaaacgtatc
   387601 acaaatgcat tatgccaaac aaggtgttat cacacctgaa atggaatata ttgccattcg
   387661 tgaaaattgc aaatggcaag aatataaaga ccaaattggt cagaaaaaag gcgagagttt
   387721 tgatgctaat atcccagatt taattacatc tgagtttatt tgttctgaag ttgctaaagg
   387781 acgtgcagta attcctgcta atattaatca tccagaagta gagccgatga ttattggtcg
   387841 taattttatg gttaaaatta atggtaatat tggcaattct gtattggggt caagcatcga
   387901 agaagaggtt agtaagatga tatggggtat tcgttggggt gcagatacta ttatggatct
   387961 ttcaactggt aaaaatattc atgaaactcg tgagtggatt attcgtaatt cacctgtacc
   388021 tattggaact gtgcctattt atcaagcgtt agagaaggtt aatggtattg ttgagaactt
   388081 aaattgggag atatttcgtg atacactcat cgagcaggct gagcaaggtg tggactattt
   388141 taccatccat gcaggcgtgc gtcttaaaca tgtaccactg actatcgaca gggtaacagg
   388201 tattgtttct cgtggtggtt caattatggc aaagtggtgt ttagcacatc atacagaaag
   388261 ttttatttac acacattttg aagatatttg tgaaattatg aagcaatatg acgttacttt
   388321 ctcattaggt gatggtttac gtcctggctg tattgctgat gctaatgatg tagcgcaatt
   388381 tggtgagtta gaaaccttgg gagggctcgt taagattgcc tggaaacatg atgtgcagac
   388441 ttttattgaa ggtcctggtc atgtgccaat gcaaatgatt aaagaaaata tggataaaca
   388501 gctagaagaa tgtggtgaag caccatttta cacacttggt ccattaacaa ctgatattgc
   388561 gccaggttat gatcatatta ctagtgctat aggtgccgcg caaattggtt ggtatggttg
   388621 cgctatgcta tgttatgtta ccccaaaaga gcatctaggg ttacctaata aggatgatgt
   388681 taaacaaggt gttattgctt ataaaattgc agctcatgca gctgatttag ctaaaggaca
   388741 tccgggtgca caaattcgag ataatgctct ttctaaagcg cgttttgaat tcagatggga
   388801 agatcagttt aatttaggtc tagacccaga tacagcacgt aaatatcatg atgaaactat
   388861 gcctaaacaa gctgcaaaaa cctcgcattt ttgttctatg tgtggtccta aattttgttc
   388921 tatgaaaatc actcaagaga ttaaaactat gaatgtagat gagattgcta agattaattc
   388981 tatccaaata gaaatggata aaaaatctgc agaattttta aaaaataaca gtgaaattta
   389041 catgaaaaaa aatacttaaa ttttttatta acttaattaa aaaatgattg actatttgct
   389101 taaagctctt taaacagcat tgagttggag aattcagatt cttgtttatt gaagcaatat
   389161 tatattaggt attatatttt ttagatattg tagattatat aaatttattg attaattgta
   389221 atgtattttt tactgcacct tgtttactat acaagtattg ttgggcgtta tatcctaata
   389281 ctttgcattg tttttcatca tttagtagca ttataattat tttaaataaa tcactcacat
   389341 tttgaattag aatagcagca ttttgttcta gtaaatctaa tgatatttca gtaaagttaa
   389401 atgtgttaga accaaatata ataggtttag caaaagcagc aggttcaagc atattatgtc
   389461 caccagtatt gcttaaacta cctcccatga aaacaatatt agcaatatca aagtaggaca
   389521 tcatttcacc catagaatcg cctaaaagaa tttgaacatc tcgggcaggt tggttttctg
   389581 aacgacgagc aatatttaaa ttagcatttt tagctaattt atagactaca tcaaaacgtt
   389641 ctggatgtct tggaatgata acaagtaagg cattaatagc gtatttattt tttgagtatt
   389701 cgttaataat ttgtacttct tcattcttat gggtgctggc aaaaataaca gttttacgtt
   389761 tgccaattat tttttgtaat gcattgctta ttattttgtc aggtgttgtg ttttgatcaa
   389821 atttaatatt attagttatt acgacataat catttctagc acctaattca ataaaattgt
   389881 tagcagaatt ttgattttga gcagcgatta agctgatctt atttaaggtt tgtttaacta
   389941 aattagaggt aaatttttgg tatttttctt ttgattgttg tgataatctg gcgttgataa
   390001 gtagtattgg gatgtttctt ttgttgagtt cgtggattaa attaggccaa atttctgttt
   390061 ctaatattag gcatattttt ggattaattt gcttaatata atgcttaata atcaatggta
   390121 aatcataagg aaaataaaga ttaactacct tatctctata ataactgata actgcatcag
   390181 aacctgtagg tgtagttgtg gtaactaata atttatgatt agggtgttgt ttaataagtt
   390241 gatcaataat aacaatagct gctttaaatt cacctataga aacacaatgc acccaaataa
   390301 taggttcttg tattctagta attaagccga gtcgttcatt aattctttgt ttaaatttag
   390361 gtgtttttat gcctttaatt attaacctta ggattataaa tggtaacaaa atatatccta
   390421 ttatattgta gagactttgg tccattttgg aagtggtata atatggttca ttatatttta
   390481 gcggttttga agtcctttat gaaatttgtt gattctgcca gtgtccgtat tgaagctggt
   390541 aaaggtgggg cagggtgttt gggctttcgt agagaaagat atatctctga tggcggtcct
   390601 gacggtggtg atggtggtga tgggggtcat gtatattttc aagggcaaga tggattaaat
   390661 acacttagtg aattttgttt taagcgtttg tttagagcaa aaaacggaca acctggatca
   390721 ggccaaaata aacgtggaaa atcagcgcaa catttgacgg tagagattcc attgggtact
   390781 aaggtttatg atcttgtaac tgatgagtta attggagaaa tgactaaaca tgaacaaact
   390841 atactagttg ccaagggtgg ctttcatggt ttaggcaata cacgctttaa atccagtatt
   390901 aatcgcgctc ctagagaaac tacgccaggt tttccaggag aggttcgtga gattggtcta
   390961 gagttaagcg ttatggctga tattggtctt ttgggtatac ctaatgccgg taaatcaagt
   391021 ctgattagac aaatttcaag tgcaagacct aaaattgctg actatccatt tactacgtta
   391081 catccttcgt taagtgtggt atctttctgc gataagcata ttgttatggc agatattcca
   391141 ggactaattg agaatgctag taaaggggca ggtttgggtt ttaaattttt aaagcatttg
   391201 tcacgtgcaa aagtattatt gcatgttgtg gatattttgc cagttgatgg gtctgatcca
   391261 gttaagaatt ttttaaccat tgaaaaagag cttaaaaaat atgatcaaga actggccaat
   391321 aaggaaaaat tattagtgat taacaaaata gatttattgc cagagaagga taggaatact
   391381 atggttcaga gcttactaaa agatatttgt tataagggaa aggtttttaa tatctctgct
   391441 ttgaatggtt taggttgtaa agatttagtg gctggattat ttaaattagt gttaagaaaa
   391501 tgaataagca aagatgggta attaaaattg gatcttcgct tttaactaat gacggtaagg
   391561 gcttagataa aacttttatt gctactttgg taaagcaaat taaagaatta aagcaacaaa
   391621 atattgatat tattttggtt tcaagtggtg caattgctga aggtatgaaa cgtctaggtt
   391681 ggcatgggcg tcctgaaaat atacataaat tacaagcagt agcagcagta ggtcaaatgg
   391741 gcttgataca aacttatgaa actttgtttt ctcagtataa tattcacact gcacaagtac
   391801 tattaacaca tgttaattta gctaatactg atcaaagtaa taatatttct gctactttaa
   391861 atacattatt aaattttgat atagtgccaa ttgtgaatga gaatgatact gttgctacag
   391921 atgaaattaa atttggtgat aacgatactt tagcagcatt agtggcaaat ttggtgaatg
   391981 caactcaatt ggttattttg acagatcaag gtggtgttta tgatgctgat ccacgtcaaa
   392041 atgctaatgc taaattgatt gataaaattc atgtgaataa cgaaagatta acacaagttg
   392101 ctaatagagc aggtgggtca ttaggctctg gtggtatgta taccaaagta ttagcagccc
   392161 aaatagttgc taaatcaaac gtgattacta ttattgcctc aggcagacaa gcaaatgttt
   392221 tgtctaaact gtacgaaggc gaacctattg ggacattgat ttattgctag catatattgg
   392281 attagggtcg aatcttaatc accctaaaaa acaaattaaa aatgcattga ttgcacttaa
   392341 ttatactaaa ggtattaagg tggggggttt atcaaatatg tatcaatcta agccgattga
   392401 cggttcaaag caacctgatt atattaatgc catgtgtcaa gttgatacac acttaactgc
   392461 attagaattg ttgcatgttt gccaagatat tgaaatcaaa cagcaccgtg tgcgcgagaa
   392521 aaaatggagt gcaagaacca ttgatttgga tattattatt tatggtgtgc aagtaattgt
   392581 ttctacacaa ttgattattc cacatccgaa aatgatgaat agagcatttg tattggtacc
   392641 gttagcagaa ttagagccta atttgaaggt gccagtttta gggcctattc aaaatttaat
   392701 tgataattta gatactacta aattggttaa attatgaata ttgaagcact aaaggtcttt
   392761 aaagaatctg gagaaaaaat tacttgctta accgcttatg atgcttcatt tgcatcagtt
   392821 tttgatgcat gtggcattga tattatttta gtgggagatt cacttggtaa tgtcattcaa
   392881 ggtgacaaaa atacattgga tgtaagtatg agtgatatga tttatcatat gcaagcagtt
   392941 gctaaaggta cacaaaatgc attaaggatt gcagatatgc cttatcaaag ctatacctat
   393001 gctgaacaaa ctttaacaaa tgctaagcgt ctaataatgg caggtgcaca aatggtaaaa
   393061 cttgaaggtg gatgtgaaca tgaagcatct tttagaatct tacaaggtaa tgatatttct
   393121 gtttgtggac atttaggttt acaaccacaa tcagtagtag aaatagatgg ctacagagtg
   393181 caaggtagag gaaaacaagg cgctaataaa attattaaaa atgctttagc attagcttct
   393241 tggggtgtta aagtaatagt gttagaatgc gtacctgctg aattggctaa acaagtatcg
   393301 caatctgtaa gtatccctat tattggtatt ggtgctggtt tggattgtga tggacaggta
   393361 ttagtaagtt atgatatgtt gggtgtgcat gtaaggcatg tgccaagatt tgttaaaaat
   393421 ttcttaactg ataatggtga tgtaaaatct gctgttaatg cctttatcaa ggctgtaaaa
   393481 gataagtctt ttccaagcaa gaagtacagt tattaatgaa gttatgctat caaaatattc
   393541 aaataactga gcttgttaac gattggcacg agcaagagaa aactattgcg tttattccta
   393601 ctatgggtgg tttgcatcaa ggacatttat cattaattga tattgctaaa caaaaagctg
   393661 ataaagttgt tgttagtatt tttgttaatc cagctcaatt tgataaaaat gaagatttag
   393721 atagttatcc acgttcactt aatgctgatt tagtagaatt agaggaaaat gttgatagtg
   393781 tttttgtccc agatgttaaa caaatctatc ctaatggcat cagtaaatat attgatgttg
   393841 gtatgattgg gcgcatttta tgcggtaaaa ctagaccgca tttttttaat gggatgatac
   393901 aggttgtgga aatattgttt gaaattgtac gacctaatgt tgcaattttt ggtcaaaaag
   393961 attaccaaca attgttagtt attaagcaaa tggttaaaaa tttatcattg gatatatgta
   394021 tagaatctgg tgaaatcatt agagaaaaaa gtggcttagc aatgagtact agaaatcagt
   394081 atttatctga aaatgatgct aaaatcgctg ctaatttgta caggatatta acctatgtta
   394141 agcatgaggt tttacaaaat aaaaaaattg atgtgttaaa aaaaatggca gaatctgact
   394201 taaaacagca ttttaaattg gattatcttg aagtgttaga tgcaaatacc cttaaacaaa
   394261 ttactgataa tacgtgtcaa attattatat tatctgcagt atttttaggt tctgtacgac
   394321 tcattgacaa tatcattttc ttaaaaaagg ataattatgt ttaatattac tgataaagca
   394381 aaagtttata tggctgattt atttgcccaa caagatgaaa aagaccttgg cttaaaggta
   394441 gatattgaaa aggcaggcac acctgctgct acagttattt ttaatttttg ctttcctaaa
   394501 gagttgagta aaacgtatca aaaatttgaa tataaagggt ttgatgtcta tattaataag
   394561 ttaaattttg tatatttaaa agactcagag gttgcattaa aagattcgag tgttggtaaa
   394621 aagttaatta ttacagcgcc taatgccaaa ggcgaagaac caaaagaaga tgcgcctctt
   394681 gaagaaaaaa taaaatacgt tattgctgct gatatcactc ctgggcttgc ttctcatggt
   394741 ggttttgttg aactagttgg gattactaag caaatagacg ttattcttaa ttttggtggt
   394801 ggttgccagg gatgttcatc ggttaaatct actttagaac aaggtgttga ggctcaactt
   394861 aaagcacgct ttccagaaat taaatctgta cgtgatgtta caaaccatgc aaatactgat
   394921 aatgcttata tgtaagtaat attttattgg gttgacaatg tagtgtaaac ttaacggtta
   394981 tgattactgt cattgatgct agtattaaag agcgtagaga cgctaaggca gcgcatgaat
   395041 tatttactat taatacggtt attgtccatt tattttttac tttggggttg attaaattgc
   395101 tcaatattga catgaatagt gcaatttatt tatctatttt aatttccttt gtcattatca
   395161 tctatactta ttttcgaact aaaaaagcta aaagtaatga tgcgtatcta gtttatttac
   395221 actggcagct ttcacttaat cgttacaaat tacttattag tgcttatgtt ttttattttt
   395281 tagttacttc actagggttg attatttcaa cagatgtacc tataagtatg gacggtataa
   395341 gaattattga ttcaatttta agtttattgg gtatagtacc attatttttt tgtattttac
   395401 tgtctgttgt attaggttct ggttcaatgt ttaatgcggg tcgtagtgaa attaatcaaa
   395461 aattagtaca aaaatatcct aaaagttagt gaatgagttc tctttaattg aaacttattt
   395521 taattggggt agttcgagtt tagctaattt agggattggt gatgattgtg ctgtgattaa
   395581 tatagatcct aattatcaat tagtaactag tgttgatact ttgattgaag gtgtgcattt
   395641 tcctttaaat actagtgcaa gtgatattgc ctataaatct ttagcagtta atttaagtga
   395701 tttagcagca atgggggcac gtgcaaaata tttcacactt gcactaacat tgccaaatat
   395761 taaaaagaaa tggcttagtc aattttctgc ttcacttaaa tccttatcag atgaaattgg
   395821 tattatattg gttggtgggg atactacaaa aggtacgtta agtatcacta ttaatgttac
   395881 tggtgtagtt gaaaaagaca aagcattatt acgttcatcc gctcaagtag gagatttaat
   395941 ttttgtgtct aatacgatta gtgatgcggc ttatgcttgg aagcaattac aaaataatca
   396001 aataccttct gagtatgcta ttaaccactt taatcgacct aagccacaat tagttttagg
   396061 gcaacagtta tcaactattg ctaacgcttg tattgatatt tctgatggtt tagaacaaga
   396121 tttaaagcat attcttactt gttctaatgt aggtgcgagt atcaatattg atgatatccc
   396181 attgactaat gaggttaaaa cttatattgc aaaaactaat gattggtgtt tggtactggc
   396241 aggtggtgat gattatgaat tatgttttac tgtaccagtt aaaaatatga atttactaaa
   396301 aaacttacaa agtaaaaaca atgttacagt tactcagatt ggcattatta atgattctat
   396361 gatgttaact aaaattggaa cttttgataa gcaatgttgt tcttatcagc atttctagtt
   396421 agtaaataga tattttttgc ttgtaaaata tattttaaac ttcttttttt tctgcaatgg
   396481 ttttacaatc aatacattca tcagcagtag gacgtgcttc tagtcgcatt aaggaaattt
   396541 cagcaccaca tgttttacaa aagccataat cgcccagttc aataatatgc aaagttttgt
   396601 caatttttcc aatcagtttt ctttcacggt cacgtgtcct taattctaaa gcaaattctt
   396661 cttcaagagt agctctgtcg ttaatatcag caacttggtt tgaatcttct tggatatgat
   396721 taatagttga ttcagcatca tcaactaact gttctctcca tgcgtttaac ttatttttaa
   396781 aatgttcaag ttgagtatca ttcataaact tctcattttt cttaggttga taatcaagaa
   396841 tttcttgata aattgattgc gacataataa ctagattaat taaaaatagt atgtttatac
   396901 ctaaactacc ttaaaatagc aatttatttt ttatgttttt tatattaaat tttttatggc
   396961 attagaagca ttaatctttg atgttgacgg aactcttgca aatactgagc gtgatggaca
   397021 tttgacagcc tttaatttag cgtttaagga attagactta gattggcatt ggtcaaacaa
   397081 aatttatcat gagttactta atgtaacagg aggaaaactg cggattaaat attatttaac
   397141 aaaatacaat caaacatttg agcatcaata tttggatgat tttatcgatt ctattcatca
   397201 gctaaagact aaaatttatg tacgtttaat gagtcaaggt gcagtacctt tacggatagg
   397261 cgttaaacgt ttgtttaatg aggcaagaaa agccaatctt agattggcaa ttgccacaac
   397321 gacaacgcct attaatgttg atgctttgat tacaagtaca ttaggatctg agtcactaga
   397381 ttggtttgag gttattggtt ctggtaatat tgtgtcaaag ttgaagccag ctggtgatat
   397441 ttatacttat gtattaaagc agatgagatt ggatcctgca aaatgttttg cctttgaaga
   397501 ttcacataat ggcattattt cagctaccga ggcggggtta aaaactttga ttactactaa
   397561 tgaatatacc aagtcgcatt gttttgatgg tgcgatggtg gtgcttaatc atttaggtga
   397621 gtctaatgta ccgtttcagt taattaaggg cgataaaact aatgcaactt atgttagtat
   397681 tgattattta aaggaacttt atgcaaaata ttgttagccg tattaaacga gatgttgtta
   397741 atgaggttgt tagaaaaact caattagaat ttgccagtca aattagtatg catttagata
   397801 ataaaattta tttaaaacgt gaagatttaa cccctgtaca ttcttttaaa ttgcgcggtg
   397861 cttatcataa gattcgaaca ttaaacattc gacaattatc taaaggtgtg attacttgtt
   397921 cagctggaaa tcatgcacaa ggtgttgctt tttctgcaaa aaaattaggt atctatgctg
   397981 ttattgtgat gcctaaaatt actccaaaaa ttaaagttga ctcggttaaa tctttaggtg
   398041 cagaagttat tttatttgga aatagctatg atgtggctta tgatttttcg caaaatatcg
   398101 ccaagaaaaa aggatataca tttattcacg catttgatga tcttgatgtt attgctggac
   398161 agggaacgat tgcttatgag cttttggagc aattagatga tattgattat atttttgttc
   398221 cagttggcgg cggcggttta attacgggta ttgctagtgt gattaaaacg cagcgaccaa
   398281 agattaaaat tattggtgtt gaacctgttg gttctgctgc attcacacgt tcaattacta
   398341 gtaatacaca tgctgtttta gacgaggtag atgtttttgc tgagggtgtt gcggttaaga
   398401 aagttggatt tgaaaacttg agaattgcta aaaaattggt taatggtact gttctggtta
   398461 gtaatgatga gatgtgtgca gcaattaagg atatttataa tcaaaatcgt tatattgttg
   398521 agccttctgg tgcattagct ttggctggga taaagcgtta tatttttgat aaacaattgc
   398581 ataataataa tatcattagc attgttagtg gcgcaaatat gaattttgat cgtttgcgat
   398641 atattactga gcgtgctaat ttaaatgagt ataactagag ggttttttag ttcattaaat
   398701 aagtattctg ttaatgaggt tgttttattg ttttagattt tttttgaacg cctatgaatt
   398761 ttacttaatt ttataaaaaa attagtagtt attggaatat tttataatgg tacttatttt
   398821 tggtagtgta taagttagag atacatctaa ctttaaatag gtatttttta tctttaggtg
   398881 taaaagccaa tagatagtgt tttcttaggg atagtaaaaa ataatattga tatagatgga
   398941 aattttttag ttagaaagag agtcttgttt attaagtaag gatttttagt tattattgtt
   399001 ctgatgcatt agtttaactg atagttataa aaaagtatgc gtcgtgttgg gtttagaagt
   399061 agtttagagt gtgtgtaggg ttttgataaa gtgattcaat gctgctatac atctgataat
   399121 taatatcact taacaactta caaaaggttg aagtagaaat ctttagtggt attgttagtt
   399181 atggtaatca tataagggta atattaacgg tattagaggg gaaaggtatt tacaaataga
   399241 tctaattggt tcaatagatt agttatatat atttttaata tatgtaacta agatagacca
   399301 gtaataagcc tttaattgat ataaatttat agttctaagt ctttgtataa aggcgaagag
   399361 gtagttaaca gaatcaaaat gaaacttgtt cttagaaaat taacaatgtt aaagagtaat
   399421 agtattacaa tagtgtttag taatagtggt aattttagtt ataaaataaa acttatctaa
   399481 gcgatatact caagtaattt aatatttgtg tgaatgctct atttcggtta gaatagtttt
   399541 tgtcgaataa aatgggctat aagtattttt ttagaataga aaaacttttt cttgaaatat
   399601 tgtattagat aaataaattc agtgctaaac cattggtaat gccgttttta acaaaaacaa
   399661 tattaatatg gtaataatta atcacaaaat tattaccata ttttgtatct taaatttaaa
   399721 ggtaagaggt tatcaacaac attgattaaa taactaaaac actttagtca attagttgtg
   399781 agagtaattt ttgaagattc tcaattatga ttaaaaactt tgatttgaac aaatttttag
   399841 gtaagcgaat actatttaag tagtaaatat gctaaaatta tgcagtttct aactgcataa
   399901 ttaccctatt tatgatttat caacacattc aaatacctcc aaagggtgaa aaaattagct
   399961 ttaaaaaagg agttattaaa gtaccaaatt atccaattat tacttatatt gaaggtgatg
   400021 gtattggtgt agatgtatca ccggtgatga aaaaagtgat tgattctatt gttgctaaag
   400081 catataacgg ttcaaaagca attcaatgga tgaatattta tgcaggaaaa aaagcaaatg
   400141 atatttatgg tgagtattta ccacaagaaa ctttagatgc tataaaggaa ttttcagttt
   400201 ctattaaggg tccgttaact actccggtgg gtggtggtgt tcgttcttta aatgtagcta
   400261 ttcgtcaaat gttggattta tttatttgtc aacgtccagt taagtatctt aaaggtactc
   400321 cctcaccagt caaagctcct gaaaaggttg atatggttat ttttagagaa aactctgaag
   400381 atatttatgc aggtattgaa tatcaggaag gcactgctga ggtaaaaaaa gttattgatt
   400441 ttttacaata tgaaatgggc acgaaaaaga ttcgttttcc tgatacttca ggaattggca
   400501 ttaaaccagt ttctaaagag ggtacagaac gtttagtacg tgcagctatt caatatgcta
   400561 ttgacaataa taaagattca gtaactttag tacacaaagg taatattatg aaatttaccg
   400621 aaggtagttt tagaaattgg agttatcaat tagcgtgtga tgaatttggt gcaactacct
   400681 ttggtgatgg gccgtggaag tcgtttaaaa atccaaacac aggtatggta attataatta
   400741 aagatgttat tgcagacgct tttttgcaac aaattctttt acgtcctgag gaatattcgg
   400801 tcattgctac acttaattta aatggtgatt atatttcaga tgcattagcc gctcaagtag
   400861 gtggtattgg tattgcgcca agtgctaatc tttcggatac gatagcggta tttgaagcaa
   400921 cacatggtac agcgccaaaa tatgcagaac ttaataaagt taatccaggt tcaattattc
   400981 tttcggcaga aatgatgctt aggcatatgg gttggataca agcagccgat atggttttag
   401041 aggcaatgtc taatgttatt caaaataaaa ctgtaactta tgatttagaa agacttatgg
   401101 atgatgcgac actgttatca tgctctgaat ttggggatgc gctcattgat tatatataat
   401161 caaattattg ttttttaata aatttatcat atattttaat taggataaaa aatgaaaaac
   401221 gtaataaaac tggtggtaat tgctacagta gtagttgctt catttgcata ggtattttag
   401281 aacaacacaa acggttatgg taataataat ggttagagtt ggtatattgt caatgatctt
   401341 tctaactgga gtatttttta gatgaaaagt ggtttgttat aataataaag ataccaccaa
   401401 taatatatct actgttttag tatatgacaa ttcaactggt gtggtttctg aaaatgctaa
   401461 ggaaaaatat aatgctcacg ttaaaggttg tacagataga aaacttgtag gaaatactga
   401521 cagtagaaat caaaaatatt caaacggtgt taaattaagg ctactttatg gtggtttttg
   401581 ttatcactat atttaaattg aattaataat aaaattttta gtattctttt ccatattttt
   401641 gtaattggtt ttagtgagat tatctagtga tttttttatt tttctatttt ggtatgaatg
   401701 ctttaataga aaaatgtatg atagatttct ataatgttat tatcagttaa tatttatcgt
   401761 ataatatcta atagagacaa cagagtctga tacttaaaac cctcttaata ataagagcgt
   401821 tatactttta aatttggaga ttaatatgaa aaagataatt gctattgcta ctttagtagc
   401881 tgctacatca gcatcagctg gtttctttaa caatagttca aataataatg gctacggcta
   401941 tggtaatggt tcaaataatt ggggcccatt tgatggtggt tctaactttg gtccaatgaa
   402001 tggaggttct aattggggtc ctttttcagg tggtaacaat tggggcccat ttgatggtgg
   402061 ttctaacttt ggtccaatga atggaggttc taattggggt cctttttcga ataataatga
   402121 tatgaacaat gattctgact ggggtttcca ttataacaat aagaataaaa ctaaaaatgt
   402181 ttctaatgta accgctgacg gtaaatatgc aggtactgct gatgcatttg ctaaaggcca
   402241 agctgatgca tttgccaaag gccaagctga tgcatttgcc aaagcccaag ctgatgctta
   402301 tgctaagggt tatgcagatg ctaaggctaa tgcaactgtt gatagtcgcg atcaagtgat
   402361 tgttaagtaa gttagtttta gtatttaaga atcaataaag atcatccttg tagggtggtc
   402421 ttttgcgttt gagtaaaact gtagtagttt tagaaacttt agcattagct taaacaatta
   402481 tgtttataat aacggctatt tgtggttatg ttattgagtt ataacttttt tagtataaaa
   402541 ccatactaac ttaaaaagat ataaaaataa ctgattttta tattgcttta gtattcatgt
   402601 atcattataa ttttatctat tattccttga tagctcagtt ggtagagcaa tggactgtta
   402661 atccgtttgt cggtggttcg agtccacctc gaggagccat atttatatgg ttatatcatg
   402721 taagttattg aataatttat gatatgtatt aaaatatcta ctatatacat caaagaaata
   402781 gtttgtacta ttatgtctaa tgacataata aatctatatt taaatagttc atttagtact
   402841 cttatatatg aagatatgga tcactatatt aaacttaaat gtagtgacta gtaaacatta
   402901 atatgcaatt aagtgttttg gtgataatga ctttatttac tacattatat tagtagatga
   402961 tagttatcat tgttaagaat gtgttaataa attcgtgtta tttattgttt aattatagaa
   403021 caataagctg tatatgaaat atagattata aattaactca tatataagag agatatgcgt
   403081 aaaatattat gacttattta ttgattgttt tgatgtattt taagcgattt ttttagacag
   403141 aaaaaacaaa tttaaaactt taaagaattg atataaagta tattatttat ctgtatatct
   403201 attatgtatt tttcttaata ttttctatat ttagtatgtt gaaagatagt tttatatcta
   403261 ggtaattcaa tataaattaa ttatacttat attttaaggg cgtacttctt aaatatggaa
   403321 acagaatatt tatattactt tagtactaat tgttgtgttt gattttccaa agtatttaat
   403381 ttttatctct aataatttaa gatgatgatt cgtgaaaaat ggttatttgc accaattaat
   403441 aacttaggaa aaattaaaga tacatggtat tgtaattttg gtgttttttt gccttatgaa
   403501 aatgatgagt ttgatatttt tataaaagaa gaacgtcaaa ttcttaaagg tattaaacat
   403561 aatgagaaac tattaaaaga atttacttga taaattagac aagtaataga taaatcactc
   403621 tatatagaag gtagtataga tattgtattt ttcatacaat aaaagtactt attgttaagt
   403681 atagaagaag ttctgagaat tgtttaactt aacaagttta atgctgatat tgtttattaa
   403741 ttataaataa gtcaaggaga agaaaatggt acataaaatt gaatgtgaac attgtgggaa
   403801 taaaatcaat attgaacaat caatatggaa gagtatatca atagatctaa attctaaata
   403861 tgtcaaaaaa gatgttgaaa tgaaagtaag agagaaagcg cttaatgatg aaaaagagaa
   403921 acaggatgaa gaggttgctt ttttagtagc acaggaaaga agtgtattag taaaaaaata
   403981 caacgatgca caaaaaattc aagaagaaat gattcaaact gaagttgaca aaagattgat
   404041 tttagataaa gaattattag ataaacagat acgtgaagag gttaaaaatg atttagaaga
   404101 tgctaaacag aaaaatatag aaaataacaa aattaaaata gaaaacatga ggttagaagc
   404161 tactgttaat acaatggaat ctcaacataa gatagatatc gaaataaagg tagctgaagc
   404221 tattaattta tctgaaaaaa aagctataga agatagagag cagcaacgaa gtgagaacga
   404281 cgtgaaaatg aaacaaatgc aaaaaagtat agaagatgta caccgccagt ctaatcaagg
   404341 ttccatgcag attcaaggcg aagctcaaga gcaaactatt aagagttttt taaaatataa
   404401 ttttccatta gatataatcg aaccaattaa acagggtgct cgtggggggg attgtttgca
   404461 acatgtagta aacaataata atcaaaaatg tggaataatt tattatgaaa gtaaaagaac
   404521 aaagaacttt gaaaattctt ggatacaaaa attcaaagct gatatgcgtg agaagaatgt
   404581 agatataggt gttttggcaa cacaagctat gccaaaaggt atgaagcgag ctggattagt
   404641 aaaaggtatt tgggtatgtt tacttgaaga gtttaaaatg atatctcata ttcttagaaa
   404701 gcagttgatt gaaatatata aaattaggag tattagtgaa aatagagaag atatagtaag
   404761 tcatttatat agatatttaa ctagtagtga atttaaaatg gatatggaag caatagttga
   404821 aggttttaca gagatgagat cagatattga ttcagaaaaa aaagccttta atagaatatg
   404881 gagtaaacga ggcaagcaac ttgaaaaaat tatgctaagc actgtaaata tgtatggatc
   404941 actccaaggt atttcaaata attctattga aacaattaat gggttggagt tgcctggagc
   405001 tgattatagt caaattaaaa aatgagagag tgtataaaat tagaccatac agattttata
   405061 ataagttttt ataccttgct gagcttatca atagcttttc tgatattatc catgtttgta
   405121 gcaaatgaaa aacgtatata acctggcata ccaaaatctg aacctgggac taatgcaata
   405181 ttcaatattt ctaagcagta agtagagagt tcaatatcat tttttaaacc gagacggcta
   405241 attaatccct caacccttgg aaaggcataa aaggcgcctt gtgatttagg acattcaatg
   405301 ccattaattg tgtttaatgc atcaacaatg aaatcatgcc tttttttaaa agcacgaacc
   405361 attatgttga taatgctttg atcaccattt aaagcttcca aagcagcggc ttgggaaata
   405421 gaacaaggat tagaagtgga ttgaccttga atttttttca tagcttgaat aatatttttt
   405481 gggcctgcgc catatccaat tctccagcca gtcattgcat aggctttaga gactccattc
   405541 agaataatag tgcgatcttt tagtgtttta tcaaccataa caatgttgac aaaattctca
   405601 ttattattcc aatgaatatg ttcgtaaatg tcatcagtta tgattaatat ttttgggtat
   405661 ttttttaata tatttgccaa tgcttgtaat tcagctttag aataaactac acctgttggg
   405721 ttggaggggc tattaataac aaataattta gtattattgg taatatttga ttctaattgt
   405781 tttggtgtaa ttttaaaatt ttgttctaat cctgttgtaa taataattgg tgttgcgtca
   405841 gctaaaagag tcatgtctgg ataacttacc caaaaaggtg cggtaataat cacttcatca
   405901 cccttgttca gtacggcttg gcaaaggtta taaaacactt gtttcccacc tgatgaaact
   405961 attacttcgg tattagtgta agttaagcta ttttctcgtt taaatttatc aataatagct
   406021 ttttttaata tgggcgttcc atctaccatg gtataacgag tttgaccatt tttaatagcc
   406081 tgtatagctg ctctttgaat atttttaggt gtatcaaagt ctggctctcc tgaacccata
   406141 gatataattt gaataccttg agattttaat tcgttggctt tagcagtgac ttcaagtgtg
   406201 gctgatggtt taattttttg aattctatcg gaaagatatg ctgacatgat tattaataat
   406261 aaaatagatt aaaattgggt gtttatgtta atgaaaaaat cttttgtgtg gacaataaat
   406321 tttaactgat atcaaattac tcatagtgga gatcagccaa aagcgattag aattttggtt
   406381 gacagcgtga attgatggtg ataagttcca agtattactt ggtgtaattg gtttaggaaa
   406441 gaccttttca ccatagctaa tgttatttac tagactaaat accctagttt aattatagcc
   406501 aaacctatta tcaatactct tgatataaat ttaaccaata ataaaataga aaaaatgaca
   406561 tatatacagt gcttattcaa cttttactgg tgcaattatt aaaataaata taaaatatta
   406621 gaagagaaaa tgtatagttt gctactgatt tagagtttga atatgcagta gatatgcgta
   406681 atcagattaa acaactcaaa gacacttaat ttaaaaaaat attatgatta acgctaaatt
   406741 aaacattaat gaaatatttt actccattca aggtgaagcg cgtgaagttg gtttgcctag
   406801 cgtatttatt cgtttaactg gttgtccact taaatgtaca tattgtgata ctgaatatgc
   406861 atttcatgga aataacttaa tggaaattga tgcaatcatt agtgaaataa aacaatatga
   406921 taccacttat atttgtgtaa ctggcggtga gccgctatta caaaaaaact gttatttatt
   406981 gttagataga ttggttgaaa ataattatca agtgtcttta gaaactagtg gtagcattaa
   407041 catacaagat gttaatgctt tagtatcaat agttatggat gttaaaaccc caagttctgg
   407101 tgaatctgaa caaaataagt atacaaattt taaaaaatta accgtcaaag atcagctgaa
   407161 atttgtcatt ggatcacatt ctgattttga ttggagtgta gctattttga accaatatca
   407221 tactactgca ggtgtattat tctcacctgt atttggcaat attacaccaa cgcaactagc
   407281 agattggatt ttggatcaac aattaaatgt gcgattgcaa ttacaattac ataaattact
   407341 ttggggtgat gaaaaaggaa agtaactatt gaatagatat tttttgcact tgtggttttt
   407401 tctgtttaag ttttggaata gagatactca gtatattgtt gttaaaactt gcattgatat
   407461 tattggtatc aacatcatct ggtagggtaa atttttggaa aaaactacca gatgaggtac
   407521 ctaaattgta attgttactt tgaacttttt taacacaccc tttgattaaa atagtattgt
   407581 tattggtaga aatactaaga ttttctttac tgattccatt aacttttatt tggataataa
   407641 agctatttga ttgattgtca aagtatcttc tactttgtgt tctaaggtta ctatagttct
   407701 gtatttgatt aattttataa ttcagttgtc tgaactgttg ttcaaaatcg tgccaaataa
   407761 aattgttatc aaagagacta ctattaaata aattgttgct attggcatta attacgctgg
   407821 aaattagtaa tatagataat agtagtctct tgtacattat tttttttaga atggctttta
   407881 ttaatttcat tatactaatt aatagctatg ttttcaagtc taaaatcaag ctaatttata
   407941 aatggtttaa ataattcatg atttttatat ttttaaaatt aataaagata tttttaaggt
   408001 tatcttttag gcgtaaagat gtttgcaagt tatgtgtatt ggaagtaagt aagaagctgt
   408061 tacgtccata atgttaactt gataagtttt aatatcactt atgtttattt attttgtatg
   408121 gtaggggtga acaaatctat attgaggctg gaataatagg tgtaattgat tcgatattta
   408181 agttttgagc tcgatgacgc ataacgtgat ccataatggt tattgctagc atagcttcag
   408241 caataggagt tgcacgaatg cctacgcaag ggtcatgtcg acccttggtg attacttcaa
   408301 taggtccccc tcttttatca atactttcaa ttggtaggct caaacttgaa gttggtttta
   408361 gtgcaataga cactaaaata tcttgacctg aactaattcc accaaaaatg ccaccagcgt
   408421 gatttgactt aaaacctgtt aaagtaatgg catcacgatg ctcagtacct ttttggttaa
   408481 ctactctaaa tccatcgcca atttcaactc cttttactgc gttaatgctc atcatactat
   408541 gggcaatatc tgcatctaat ctatcaaaaa tcggttctcc tagcccaaca ggcatattat
   408601 ttactatgat gttgattcta gcacccactg aatcacctga ctttcgcaaa gtatccatat
   408661 atttttctaa aattttaact ttattagcat cgaggcaaaa aaatgggttg ttgtgtactt
   408721 ctagccaatc agaattttca attttaatag gtcctagttg agataaataa cctttaattt
   408781 taatattgta ttcttgcttt aagtattttt tagcaatacc accgcaagca acacgcatag
   408841 cagtttctct tgcagaagaa cgccctcccc cccgataatc tctaataccg tatttttgat
   408901 gataagtgta atcagcatgt ccagggcgga aggtatcttt aatatttcca tagtctttgg
   408961 aacgctggtc tgtattttga atgatgagtg ctattggtgt acctgttgtt tttccttcaa
   409021 atgtgccaga taatattttt actaaatcct cttcatggcg ctgactagtg tggcgggaag
   409081 tacctggttt tctaaggtct aaatcatctt gtaaatcaac ctcagtaagt gccagtcctg
   409141 gcggacaacc atctacaata ccaattaatg cctcaccatg agattcacct gctgtggtaa
   409201 ttgtaaataa ttttccaatt gtattaccac tcatttacca ttccttatgt aggataatat
   409261 tgtcttagtt tgttctttaa gtctttaaac atatgttttt gaaaagactt tatttttata
   409321 gggtttggat tattttttaa ttgtgtcata attagtgagc catgattttt ataaaaaacc
   409381 tacttttgtt aatattctct ttaaattcag ttaagttttt tcatcactgg taaattcaaa
   409441 gtttttattt ttcatttttt atattactat tagttgtaaa cgctccactt tgagatttgt
   409501 gatatttaga gcaacgacac atgatacata acataataat tttaaaaaaa tctaattata
   409561 cctagtctat ctaactagaa tgttatatag tattataaga ttattaatat ctgtgtcaaa
   409621 aaacttataa atcatactaa aatatataat actcataact cttaaggtta aagtattatt
   409681 gtaaaggctt taatgttaat tttttttgca tttttacttc tttgattgtg cccccggtgc
   409741 gatttgaaca cacgacctac cgcttaggag gcggttactc tatccagctg agctacgaag
   409801 gcaatgtgat tattatccac gatataagca cttgttgaaa tctttgcatt attttttatc
   409861 tgatttgttg atgataatat actttactta cttttaggcg gatatttatt tgaattgatt
   409921 tgtattttac aaaattgtgt aatttaaatc acagtataat cttaatattt ttttaatatt
   409981 taatttaatt taaaattaca tgaagaatat taaagttgag aatagactta tatttgcttt
   410041 agatgtgtca gaaattaaac aggctaaaga tttggtaatt caattggata atagtattaa
   410101 tttttataaa attggtatgg aattattaat gacagggcaa tactttaatt tgcttgattg
   410161 gttattagaa aaagacaaac aagtttttgt ggatttaaaa ttttttgatg ttccagaaac
   410221 tgtaggtaga actattaaac gtttaagcca atatggtgct acttttgtca ccatccatgg
   410281 caatcaagcg cttatggaaa aagctaatga aaataaatac aatcttaaaa ttttagcagt
   410341 aactgcgctt actagtattg atagaggtga tttagatgat ttaggtttta attgtgatgt
   410401 gttggagttg gttgtttctc gtgctaaacg tgcttttgaa gcgggttgtg acggtgtagt
   410461 atcctctgga cttgaagtgc catttttgcg taaatatgtt gacagtaaat taattgttgt
   410521 tacaccaggc atccgtcctg tggttaacga tgatgatcaa aaacgtattg tggatgtagt
   410581 aacagcgttt aactcagggt cagattatat tgttgttggt cgtccaatta aaaatgctac
   410641 tagcccatat caagctgcga cagatattca aacaattatt aaaggttgtt tttaagtaaa
   410701 attatcactt ctttagtcgc gtagctcagc tggttagagc actaccttga catggtagag
   410761 gtcggtgatt cgaattcact cgtgactacc aaagagatag tcagttttta aaatatttag
   410821 aggcttcaga ataagacaaa caacttaaac tatatatctt ttttcaattc caaatggaaa
   410881 atgtttgtaa tgccaaaaat taataatgta aataataaga ttatttagat acatatcgat
   410941 aagtgtaaac aacttcaaca ataagtatta aaactaataa tagttaaata tatcaaggat
   411001 aaatactaat tttaatttac taattaaata aagaataccg tcaaattgaa taacaatata
   411061 aaccatagta agtgctcgtg gttataatga gcatattatt ttaaattttt tgtttaatga
   411121 aagttgatat tgtaattatt ggtggcggtc catctggttt aagttttgct agcgctatgc
   411181 taaattctaa tatcaaaata ttattgattg aaagatcaag tcttgactct attgcaagcc
   411241 ctcaggtaga tggtagagaa attgcattaa cgcatttatc attaaaaatt ttaaagaagt
   411301 ttggtgtttg ggatttaatc aatcaggcag aagtttctcc tttaaaagaa gcaaaagtgt
   411361 ttgatggcga ttcaccttcg ttactgaatt ttacaactga aaatacttca atagaagcct
   411421 tgggctattt agtccctaat tatcaaatta gaaaagcgct ttatacaaaa gttaaacagg
   411481 aaaaaaagat taatattatt actaatatgg tagttgagga tgtaatccaa ttagatgatt
   411541 gttcacaggt tattttgtct aatggcgata aggtagaaac taaattagtt attgctgctg
   411601 atagtcgttt ttcagatatt cgtagaaaag ttggtattcc gaccttgata aaggattttt
   411661 ctaagcttat gattgttact cagatgagtc atgaattatc acataataat gttgctttgg
   411721 agcgctttga ttatggtaga acattggcat tattgccaat ggtaggtaat gtttcgtcta
   411781 ttgtattaac agttaaaacc aaccaatctc aagcaatact taaaatgaat gaaactgatt
   411841 ttaatcagat gatcacacaa tcatttaaag atgagttagg gaaaatgatg caaataggcg
   411901 agcgatattc ttatccattg attgcaacgc acgcgcaaac ttttatttct aaacgatttg
   411961 cgttgattgg tgatgcttca gtaggtatgc accctgtaac tgcacatggg tttaacctag
   412021 gtttaagagg gcaagctata ttagctaaat tagttaatga ggctttggat aatggtcaag
   412081 acattggctc taaatctttg ctaaaattgt atgagaaaaa gcatattaat ttaactagac
   412141 ttatgttttt tagtactaat agcattgtgg cattatttac taatgatgcg ccggtgatta
   412201 aacaaataag gcgttttgtt cttaagtttg ccgagcattt tccacctatt aagtatctca
   412261 tttttcatca tctaacacaa gataaaaagt ataaatcttt ttatttttaa tgaaagttga
   412321 tttaactggt cttaggcgcg aatttactca gagtggatta aatcgtactg atctggataa
   412381 tagtcctttt ggccaattta atttgtggtt tgagcaagct caaaaagcag atattatcga
   412441 gccaagtgct atgagtttag caacaagtga taataatgaa ataggtatta gaactgtatt
   412501 acttaaatat tttgatatgt atggttttgt gttttttaca aattacaatt ctaaaaaatc
   412561 taaagaactt caatctaatc cgaatgtagc tttgttgttt ccatggctgg ttttagagag
   412621 acaagttaaa atttctggtt atgtagaaaa gatcagtatg cttgaatcct taaagtattt
   412681 ctcttctaga cctaaagctt cccaattagg ttcctgggca tctcaacaat catcaagttt
   412741 atcctcaagg aaggtgttat tatctcaatt tgaattaatg aaggtcaaat ttagcaatgg
   412801 aaaagtgcca ttacctgatt tttggggggg gtatcgtgtt gtgccattaa agattgaatt
   412861 ttggcaaggt agagaaaatc gattgcatga tcgatttata tatcaactaa ataaaggcaa
   412921 gtggagaatt gaacgtttag cgccttaagt tacttagaac tttcttagta tcaggtttag
   412981 cacctgtcca gaattcaaaa gctattgctg cttgttcaac taacatgccc aagccatcac
   413041 taatcatttt ggcatggttg gtttttgccc aactcataaa tggagtttga tagccataca
   413101 ttaaatcgta acacaccgcg ttattggcaa tactaaaggc aatattagga attcttccat
   413161 caaatgatgc actagtagca ttgataataa tgtcaactga cttatactta attttattca
   413221 aactaaaact gcaagtatta ccaaatttag agaagttttt agctagtcta atcgctttag
   413281 aatgtgtccg attagaaatt ataacttgat taggtttctg ttttaaaata gggaataaaa
   413341 ttccttgagt cgcaccccct gcacctaaaa ttagaataac cttatttttt aatttaatac
   413401 caatattatg agttaaatct ttaattagcc caattccatc ggtattttca ccaataattt
   413461 tatcagcttc tatcttaata gtattaactg aacctgctat tttggcattt agtgtaagtt
   413521 cgtttgcaaa tttaaatgca tctaatttaa aaggcacagt aatattaaaa ccattcgctc
   413581 cttgattgat gaatgcttgt actgaggaca caaagtcatc aacaggtgct aagattttgt
   413641 catagctaat ttcaaaacca gtttgcttag caaactggtt ttgaatattt ggcgataaac
   413701 tatgatttat aggattacca aaaacagcaa atttatacat tattaacctt attttttatt
   413761 agctactttc tatttttatt tcggtttcta ttattagggt ttgttctacg tttattaggt
   413821 tgttttttct tctttccaaa taaagtattt ttgattttct caaacaagaa aattttcttt
   413881 tcaggaacgc gtgtattagg tctattgaca ttaatggcgg gaatttcagc ttgatttgca
   413941 agaccattct caactaatat atgttggggc tttgaaatac cttggtagct tttatgttgt
   414001 gattttttac cccatttttg tttattaata gtgaaattag gaaattgcat atatggatta
   414061 ggtaataaag taattttaat actatgtttg tcttctaatt ttattacctc ttggcgtttt
   414121 tcattcaaaa tgtaagtaat cacttctata cttgattgaa tggttaaacg tgctgtttgt
   414181 ttggcagcat tacagctatt ttcaagttgt cttaaaatag ttaatgctaa agttggaata
   414241 gttggagtag tgccacgacc atgacaaata gtacaaggct tttcgactga ttcagtgact
   414301 gagttcatta agcgttgtct tgacatttca agtaagccaa attgagaaat tgtaccaatt
   414361 tgaatacgtg ctcgatctaa acttattgct ttttccatgg ccttttctat tgaaactcta
   414421 tgttcttcag aagccatgtc tataaaatca atcacaatta atccaccaat atctctcaat
   414481 tgcagttgta tggcaatttc tttagctgct tcaagattag tattgtaggc agtttcttta
   414541 atgtcagcac ccttagtagc acgagcagaa ttaatgtcaa ttgaagtgag tgcttcagtt
   414601 gggtcaaaaa caatagtggc tcctgttcgt agcgatactt cacgattaaa tacactttta
   414661 acttgggttt caatgcccat atggctaaat aaagagtgtt ctgaaacatc aaaaaatttg
   414721 atgcgatcta agtagtgtgg taatacaaag ctgacaaatt ctttagcatt ttgaaaagct
   414781 tccaattcat caataataac actatcagta tcagagcgaa ggtgatcccg caatgtacga
   414841 ataatgatat cactttcttg ataaattaag aaaggtgcac catgtgctaa agccattgtg
   414901 ttgattgatt tccataagtc agtgagataa tctacttccc attgcaattc ttcaaagctt
   414961 tttccagagc cggcagtacg aatgattaaa cctgaatgtt taggtagaat aattctgtta
   415021 ataatttctt ttaaagattg tcgatctgag gagactattt gccttgatat accatgactt
   415081 ttcggattgt taggcattaa aatcatataa gcaccagcaa gattgatata agtgctaagt
   415141 gccgcgcctt tattaccacg ttcttctttt tcaatttgga caataatttt ttgtccttct
   415201 tttaaaacat cagaaatggt taatttttca ccttcagttt tagtgttatt gtataaagtt
   415261 tcggcaattt ctttaaaagg taaaaatcct tgtttttctt tgccgtagtc aacaaatgct
   415321 gcttctagtg attgttctat tcgagagatc ttgcctcggt aaatattgcc ttttgttttc
   415381 ttattaaggc tagtttctat attaaggcca gttaattttt tgttttttat aatacctact
   415441 cttatttctt cggagtgggt tgcattaatt aaaatatgat tcatggttaa gtcctagtgt
   415501 gaatggattt ggttgcgcac ataaaaggtt caacactagc gtgttaattt tgtgttaaag
   415561 tgtgatttat tcttatcata aaatgattaa aaacttattc cttaatagtt ttaaaccttt
   415621 tattatttag tttcttttaa gcgactaaat aattaattta ctttgatatg gtaacaaaaa
   415681 atccaaaata ttaatagtat ttttgtggta tttatttttg gcatataaaa aatattttaa
   415741 aaatcttttt agttgatgag aatttaaata ttaattttct aaaattatat cacaaaaata
   415801 gtatgatatt tatgcaaaga cctttattga ttaagtgtgc gaccaccatc aacattaata
   415861 atttgtccag taatgtaggt agatttggct aaaaataaaa cagtatcagc aatatcttgc
   415921 gcactacctt gttttctaag tacaattttt ttaagtattt tatttttttg aacttgatta
   415981 agtttagcta catttgttgg ccataaaatt gacccaggtg atactccaca aacacgaaca
   416041 ttgggtgcta attctttagc taaagttttt gtcatcatgg caacagctgc tttagaaatg
   416101 ctataaattg tataattttt taaaggacgt tcgctgtgaa tgtcaataat attgataatg
   416161 caaccttgat tgtgagctaa cttatcactt aaagtactag ataaaaataa aggcgccata
   416221 agattagtgt tcataataga ttgataatca tgttgattta atttatcaac aggtgttgag
   416281 taaaaaatag atgcattgtt aactaaaatc tcaagtgact tgatagcatt gcaaagttta
   416341 ttcacttctt ggatattaga taattcagct tgtaaaatac tggcagaatt ttggcgaata
   416401 ttattaagct tattcattag attgttagca gcttggaatg aatttctata atgaataata
   416461 acaaagtaac catctctatg taaagtatga cagatttgca taccaattct atacgctccg
   416521 cctgtaatta gtgctatttt catataaaat acgtcaagtg attcttgaac aaattattaa
   416581 aaatactatt atacaaaatg ctggtcctat aggttttgat gaatttatga atttagcgct
   416641 ctactatcct gcattaggtt attatagatc gggtttggaa aaatttagta aaaatggcga
   416701 ttttattacc gcaccagaaa cttcagattt atttggattt tgcttggcta atcaatgtgc
   416761 tcaggtgcta aatggtacca atgatatctt agagtttggt tcaggtagtg gtattcttgc
   416821 tactcagata ctttttgagc taggaaggtt aaaaaagttg ccacaaaagt attatatttt
   416881 agagttaagt ggtgagctta aacacagaca agcagaaacc attagtaagg tattaccaga
   416941 attaatagat agaatagttt ggcttgatga attgccatca gatttttctg gtgtggtgat
   417001 tgctaatgaa gtattagatg ccatgccagc aaaacgtgtt atttataaaa ataaacaatt
   417061 ttatgagtta ggtattgatc atcatgagaa tgaatttttt tggagaaaat tcgattctcc
   417121 ttatcaaaat gataaaatat tattacctaa taatgtgatt gaagattata gaactgaaat
   417181 aaatcttcat gctatagcat ggattgactc cttatataat gctactaata aggcgctcgt
   417241 attgttgatt gattatggca tgagtaggga tgaatatttt catccacaaa gattagatgg
   417301 tactttaagg tgttattatc accacaaggc aagtgaaaac ccatttttga atataggtaa
   417361 gcaagatatt actacatcag ttaatttttc tgatattgct gatcaagcaa gtattagtgg
   417421 tttcaaggtt aatggttatg cgacacaggc gttatttttg atttcattgg gtattagtga
   417481 ttatttgctt aaacaaaaag ataaaaataa acgtatgaat ttagcacaac aaattaaaca
   417541 gttggttcta cctagtgtaa tgggtgagag ttttaaggtg ttggccttaa gtaagaaatt
   417601 atcggtaaga ttaataggat ttgttgaaca agatctaagt ggtaaattgt aaaagatttt
   417661 tgtataaata tggatgtttc tcagacaatt gttttagcgt taatccaagg tttgagtgag
   417721 tttttaccta tctcttcttc agctcattta attttagtac caaagttaac caattggact
   417781 gaccaaggtt tgatattcga tgtagtggtg catatgggta ctctaagtgc agtgatattt
   417841 tattatcaag caatgattag gagtttgttt tttgattttt attattcaat aattaaacgt
   417901 caaattattg gtcaatcaaa gttggcatgg ggagtgctgt taggtactat tccaatagga
   417961 ttagttggta tgatatttaa agattttgtt gcagttgatt tacgttcaat agagattatt
   418021 gcttatacaa cattagtgtt tggattactt ttaggttttg ctagttggtt taatcataaa
   418081 aataaaaatc caaaaagtac aatcagttgg atagatgtta gctttgtcag tatgatgcaa
   418141 atcttagcat taattccagg aacttctaga tcaggaataa caattactgc ttgtatgtta
   418201 gtagggctgt ctaggaaatt atcaatacaa ttttcatttt tattatcaat tcctgtaatt
   418261 actttgtcat taatacttat gttgattgat ttgtatcatc agacacaatt ggttaatgtt
   418321 agtttattag tcttaggttt tgtaatttca acaattagcg cttatgcaac tattattttt
   418381 gttatcagat taatagatat ggttggtatg acaccatttg ttatctatag attaatttta
   418441 ggcgtatttt tattcttctt ataaagatat accagtttca atctaaactt ttttatcctt
   418501 aactttgttc tattggtatt atttaaataa gtctgatgtg ttaagtgtct ttacttcagt
   418561 acattaaaga ttaataaaca aaattatcca gtatttctaa tcaatggaac aatatactat
   418621 aaccaccttt aatcctaaaa tcttcgcatt ttgactaaga tttgttttgc tatgccattg
   418681 aaaatgtctt aattagatac aaaggtcatg aataaatatt tttacattaa atcatatatt
   418741 tataacggtc ggtgttgaaa gtattaaaac atttatgtaa tacaaactac ttaccaaatg
   418801 tgattggtcg tttatcacaa aattatactt accttcataa ccaatcaagt cgtgaacttt
   418861 tatttattga attaatattt ttgaaattat tcaagtaata ttaaagtgaa tatattaatc
   418921 accttgttaa aataaaagtt gcttaccatg atcgtggttg agtcttatat aggtagaagt
   418981 attagtatta attactaatt aaaatggtta ataaacctat tttgacaaaa ggtttattac
   419041 ttatttcaac caagtaaaaa ttgatatgct ggatatttag ttaataatac tagacaagtt
   419101 tagtgcggtt agcgaacaaa ctgcattaga aatagtatat gatagaataa aaaattatct
   419161 gttaatattg caatatcaat cactgctatt tctagactta gtagtggtac gatagataaa
   419221 cctgttggta cagtttattt tggttttgtg ttctaaaaac tgtttttaac tagtatcaaa
   419281 cagtttggtt ataatcgaac taaaatagta taggaaagta tttattttgt gaactattaa
   419341 agttaacagt ttgatttatt agtaaaaata aatcaatatt gaatacttga acaagtatta
   419401 ttagcatttg attagttaat tgtccttgag gtaactgttt taggtgctta actacatgtg
   419461 ataattgttt aaatcaaaac gagtaacatt tatcaaattt ttgaaaaaag cggattagga
   419521 cttagtaaag ttgttttaag ttatatagct agtagcagag gttgtattgc tcaatatgag
   419581 aaatacagtg acgttttttt aattgatatg ggaacaatat ttttaatgtc tttcatgtct
   419641 tatttgaaaa ggtaaaaaga ttcaaaatta aacatagtac tagcggataa attaatttaa
   419701 ttctattgaa caatgttatt tattattaca tagtttagct gacattttag aaaaatctta
   419761 tcaagatatt tgttattttt ttaagcaaaa tttaaaagct gaaaagctat atagaacgct
   419821 caaatcagga ttgttgttaa taggcggtat atcttgaata gaaggttgtg agggattatt
   419881 tgttaataca tttaaataag caccaaactg gttaaagttg atataaataa aattataggc
   419941 aagaatgtga ttagttctag ttctagttct agttgtattc ttaagcctgt ttgttgatgc
   420001 atactgataa taatgcttat gtagaagtag tgtaagaacc tcaataaact aactttgtga
   420061 gtaaaataaa attattactg gaataataaa tattatgatc aagcaaagaa ccattaaaaa
   420121 agaagttaaa gctagaggta tcggcattca tagtggtagt gttgtaaata tgactttgat
   420181 tcctgctaaa gaagaccatg gtgtagtatt taggcgcatg gatgtgggtg ataaattggt
   420241 gcgtgcacat agtgcctttg ttaatgaggt ggtgctttct actggtcttg aaaataaagg
   420301 tgttaaggtg tcaacagttg agcatttaat gagtgcattt tcagctcttg ggattgataa
   420361 tgttttagta gaacttgatt cgtttgaagt accaattatg gacggctcat ctgctccttt
   420421 tatttttctg gttcagtctg ctggtattga agaacaaagt actcataaaa aattttttgt
   420481 catcaaggat accatacgag tagaaaatgg tgattcatgg gcacaagtgt ctaaatatga
   420541 aggatttaag gtgtcacttg aaattgattt tgatcataaa aaagttaagg aaagtggaga
   420601 gaaattgagt attaattttt ccaaacaatc atatttaaaa gaaatttcgc gtgccagaac
   420661 ttttggttac atgaaggatg tagaaatgat gcaaagacaa aatttagcac ttggtgcgag
   420721 catggataat gcgattgctt taagtgatga tgatgtttta aacgaagatg gtatgcgtta
   420781 tcaaaatgaa tttgttaaac ataagatttt ggatattgtt ggtgacttat atttattagg
   420841 tagtaatcta attggacatt acgaaggata taagacaggg catttgctta atgatcaatt
   420901 gttatcaacc attttagcaa agcctgatac atggtctatt gagacatttg aagaagataa
   420961 ctctcctatt caattttatt ctgaagattg gcaaaattcc ttataatagt ggatttatat
   421021 tgatatatca ttaggtataa ttaataggtt attatgctaa attaaaaaga atgaagttaa
   421081 atggtgctca aatattagtt aacagtctta aaagtgaagg ggttaagcac atttttggct
   421141 atcctggtgg tgcagtttta catatttatg acgcactaaa tgcttgtgat gaaattgaac
   421201 atattcttgt tcgccatgaa caaggtgcgg cacatgctgc agatggttat acgcgggcaa
   421261 gtggcaagtg tggtgttacc ttggttacta gtgggcctgg tattaccaat gcagttacag
   421321 gtattgcaac tgcatatatg gattctattc ctatggttat catttcaggg caagtgcctt
   421381 cagcacttat tggtaatgat gcgtttcaag aagttgatgc ggtaggtatt actcgttcat
   421441 gtgtgaaaca taactttttg attaaaaata ttaaccaaat tgttaacact ataaagaaag
   421501 cattccatat tgccactaca ggccggcctg gacctgtgtt aattgatatc cctaaagata
   421561 ttactattgc tactgttgaa ccaaaacctt atccaaattc agttgaaatg cgttcatatc
   421621 aagttccatc tcgtgctgat agcgctaaaa ttaatgctgc agctgatttg atttcattag
   421681 ccaaatgtcc aattgtatat tctggtggtg gttgtattat tggtaatgct gatcaagaac
   421741 ttcgagcatt tacacgtcag ttaggctttc caatcacaca aacattgatg ggcttgggtg
   421801 cttatccagc tacggataag caatcattag gtatgttagg tatgcatggt acttatgagg
   421861 ctaatatggc aatgcatgat gcagattgtg tgattgctgc aggtgttaga tttgatgaca
   421921 gagtgacagc taatattgat aaattttgcc ctaatgctaa gattattcat attgatattg
   421981 atccatcttc tatttccaag aatgtggctg tagatatagc aattgtaggc gatgttaaat
   422041 tagtacttag tgatttaatt gttaagatga aaaccaagtt cattcaagat atttctcttt
   422101 ggtggttaca aattgaccgg tggcgttctg ttaattcttt ggcttatcaa actaaattag
   422161 gtattattaa gccgcagact gttatagaga ctctatatga agtgacgaaa ggtaatgcta
   422221 ttgtgacttc tgatgtgggt caacatcaaa tgtgggcagc gcaatactat caatttgatt
   422281 atccacgtcg ttggattaac tctggaggtt taggtacaat ggggtttggt ttaccggctg
   422341 ccatgggtgc aaaacttgct aagccagagt tgaatgttgc gtgtgtaaca ggtgaaggta
   422401 gtatccaaat gatgactcag gaattatcaa ctatgttgca atatgcaaca cctgttaaga
   422461 ttattaatct taacaatggc tatttgggta tggtgcgtca atggcaagag tttttctatg
   422521 aaaaacgtta ttccatgtcg tatatggatg cattacctaa ttttgtcaaa ttagcagaaa
   422581 gctatgggca tataggtatt aaagttgaaa aagaacaaga tttaaaacca gcattgattg
   422641 aagcgtttaa gcaaaaagat agaacagtat ttttagatat tttgactgat cctacagaaa
   422701 atgtatttcc aatgattcca tcaggcgcag gacatcatga aatgttattg gctggtcgtg
   422761 atgagatggc ctcaatgaat gatgatggat tgaatttagt atgagacata ttatttcaat
   422821 attattagaa aatgaagcag gagctctgtc tagagtggca ggattgtttt ccgctcgtgg
   422881 atttaacatt gagtcgctga cagttgtagc aactaatgat tcaactttat cacgtatgac
   422941 tattgttagt attgctgatg atggaattat tgagaaaatt gttaagcaac ttaataaatt
   423001 gattgatgta attaaagtaa cagatttaac cgcaactgag catattgagc gcgaactgtt
   423061 attagttaaa gttaatgtta atcaacaaac acaagttaat attgataagc aaattgatgc
   423121 tttttcatgt aaattagttg atgtatcaga agatatttat acgattgagt tggcaggaaa
   423181 gagtaaaaaa attaatgatt ttttagcaaa tttggatgct tcaaaaattt tagatgtttc
   423241 tagaacaggg gtgactggta tttgcatgaa aaataggaat ttaacaaaag gcgcatgaga
   423301 cgtttaaaaa tagaggaaaa tatgaatata tattatgata aaaatgcaga tttaaacatt
   423361 attaaagata tgaaggttgc tattgttggc tatggttcac aaggccatgc acatgcaaat
   423421 aatctaagag attctaatgt tgaagtagtt gttgcactta gggatggttc tgcatcttct
   423481 aaaaaagcat ctgacgctgg attaaacgtt aaatcaatta agcaagcaac tgcatgggca
   423541 gatttaataa tggttttagc gcctgatgag tttcaggctc aaatttatac agacagtatt
   423601 gaaccaaatc tgaaacaagg tgcaacttta gcatttgccc atggttttaa tattcattat
   423661 aatagaatta taccccgtgc tgatttagat gttattatga ttgctccaaa agcgccaggg
   423721 catacagtac gttcagaatt tgttaaaggt ggaggtattc cagatcttat tgcggtgttt
   423781 caggatgttt caggtaatgc taaagacact gctttgtctt atgcttcagc tattggcggc
   423841 ggtcgtactg gtattttaga aacttcattt aaagatgaaa ctgaaacaga tttgtttggc
   423901 gaacaagtgg tattatgtgg aggtacaact gctttggttc aagcaggttt tgaaaccttg
   423961 gtagaagctg gttatgagcc agaaatggca tactttgaat gtttacatga attaaagttg
   424021 attgttgatt taatgtatga aggtggtatt gctaatatgc gttattcaat ttcaaatact
   424081 gctgaatatg gtgatattac tcgcggctct cgcattgtaa ctgctgatac taaagatgaa
   424141 atgaaaaaga ttttgattga aattcaaaat ggtgtttttg ctaaagaatt tgttgctaat
   424201 gtgggcgaac ttccagccca tcgagaagtg cagcgagcac atcaaattga acaagtgggt
   424261 gaatcacttc gatctatgat gccttggatt aacaaaaata aaattgttga tcagtctaaa
   424321 aattagttat ttaataaacg tatcagttga ttagaagttt tagcgaataa catatagtgg
   424381 aaagaaaaac aaaaagaggt atttatttac taccaaatat tcttacgaca tttggattgt
   424441 tttctggttt ttttgccatt attcttgcca ctaaaagtca atatagtgat gctgctattg
   424501 caatatttat tgctatgtta tgggatggac ttgatgggcg tgtggctcgt ttaactaatt
   424561 ctcaaagtga atttggcgca cagtatgatt ctatggccga tatgatttca ttcggcgtag
   424621 ctcctgcact actaatgtat ttttggttac tgtctgattt gggtaagatt ggttggctag
   424681 gtgcttttgt atatgtagcg gcaggtgcac ttcgtttggc tcgatttaat acacaaattg
   424741 gtattgaaga taaatgttat tttcaggggt tgccttcccc agctgccgcg gcattaattg
   424801 caggtttggt ttggactaaa gaaatgattg gggttactgg ttatgatcaa aacttaattt
   424861 tagccagttg gattattctg gttggttctg gcgtgttaat ggttagtaat attcgttaca
   424921 atagttttaa agaaattaat ttaaaaggta gatcatcatt taaattatta ttatttgcta
   424981 cattgattat tattgttatt attttagagc ctagcgctat tttatttgtt ttctttttta
   425041 tttatgcact ctctggattg ttaacaacaa tggttgaagt gagaaaaaaa cgtcgtttaa
   425101 aaaaacatca tttaaaaggt taagtttcct ttataattat cctcaataat gattaatcaa
   425161 tttacatttt attcttctat agaaaacatt tctttgtttt tattataact attgccatat
   425221 ggcaatagtt atctgcgcac tatttgaaaa attttgccat ctaatttgta aatttaaata
   425281 aaccaactag gaagcttgaa tgactaataa actaattatt tttgatacaa ctcttcgtga
   425341 tggtgaacaa tcacctggtg catccatgac taaggatgaa aaaatacgta ttgctaaagt
   425401 gttggaaaaa atgaaagtag atgttattga agcaggtttt gctattgcat cagaggggga
   425461 ttttgaagcc gtacaagctg tggctaatat agtacaaaat tcggttattt gttcattggc
   425521 tagagcactt gataaagata ttgatcgtgc aggtgaggca ttaaaaggtg ctaatgcatc
   425581 ccgtatccac acttttattg ccacttctaa tattcatatg aagatgaaat tgcaaatgac
   425641 tcctgatcag gtagtaggac aagcggttcg tgctgtcaag cgagccaatc ggtatacaga
   425701 taatatagaa ttctcaccag aagatgcagg tcgatcagat gaggattttt tgtgctatat
   425761 tattgaggct gtgattaaag ctggtgctac aactatcaat attcctgata cagtaggtta
   425821 caatattcca caccaatttg gtgcaaccat taaatcttta attgaacgta taccaaactc
   425881 tgacaaggct attttttcag cacattgtca taatgatttg ggtttagcag tagctaattc
   425941 attgtccgct gtactaaatg gtgcaaggca agttgaatgt actattaatg gtttaggtga
   426001 acgtgcaggt aatacatcat tagaagagct tgttatggca gtacgaaccc gccaagatat
   426061 ttttgactgt gataccaata ttgataccat gcatatttta tcagcttcac gtttggcttc
   426121 aagtgtgaca ggttttatta tacaacctaa caaggcaatt gttggtgcaa atgcctttgc
   426181 tcatgaggca ggtattcatc aagatggtgt tcttaaacat cgagagactt atgaaattat
   426241 gcgtgctgaa gatgttggtt ggaatgctaa tcaattagta ttaggtaaac attcaggtcg
   426301 taatgcgttt aaggtcagac tggctaaatt gggtgttgaa tttaatgatg atggaagcct
   426361 taatgatgct tttagacgtt ttaaagaact agctgataaa aaacatgaaa ttttcgatga
   426421 agatttgcaa gcgctagtat ctgaaacaca gacagagtcc tgtgatgaag ctattaaact
   426481 agtgtctttg aaggtatgta cagaaactaa cgagaaaaat acggcaactg ttgtattatt
   426541 tattaatgat aaaaagaaaa cagcaacggc taatacttca ggtgcagtag atgctacctt
   426601 tagtgcaatt aattcattgg cgagtatcaa aataaacctt caattatatt ctgtttcaaa
   426661 tgttactcaa ggtacagatg cgcttggtga agtgaatgtt cgtttagagt ataatggtcg
   426721 tattgttaat ggacaaggag ttgatactga tattattact gctagtgcaa aagcttatgt
   426781 tcatggttta aataaggtat tgactgtaac taataaggca catcctcaaa tatgaatgaa
   426841 tctctaagat ctcgttattt agaggtgttt gctatacctg agtttttgca tattcaagca
   426901 aaaaatcaag atttaaatgt tttaaaaatt gatataaaat gtttagtaat tgaaactaaa
   426961 aacccttctt cattttgtca aacaggcaag actcaagatt ttttattcaa aatgttaggg
   427021 gctattggac ttaaaaaatc tgatattaag tatattagca ttaatattaa tgatttagat
   427081 caaacactta ataagtataa tgcaaaaacg gtattattga tggatgtagg tttaaagcca
   427141 tcttcaatac agcattttta catacatcac ccaagtaata ttttgactaa tgacaaactc
   427201 aaacgtgaaa cttgggaaac gctaaaaaaa gttaaacaat gtctcaagta gattatagtt
   427261 tattgggtta tagacgtcct aaattaacta caccaaatgg tgaaaccaaa ttgctaatgc
   427321 attcttgttg tgcgccttgt tctggggaaa ttatggaagc tttagcagta tcaaatattg
   427381 acactactat ctttttttat aatcctaata ttcacccaaa aaaagaatac gagttacgca
   427441 aagaggaaaa tatgcgtttt gcacaaaagc ttaacatgct gtttattgat gcagattatg
   427501 actataatac ttggtttgat cgtactagag gtcaagagta tgaaccagaa cgtggtaagc
   427561 gttgtactac ctgttttgat atgcgttttg aagttacagt tcagtatgct cagaaccatg
   427621 gttttaattt aatttcttca acacttggta tttcacgttg gaaggatata aatcaaatta
   427681 ataattgtgg tatacgtgca acacagttat ttaaaaatat ttattattgg gattttaatt
   427741 ggcgcaagca aggcggatca agtagaatgt tagaattatc taaacgtgaa acattttatc
   427801 aacaagaata ttgtggttgt gtttattcgc tacgtgacac taatcgctgg cgcgtgtctt
   427861 gcgggcgaga aaaagtggaa cgtggagtta aattttatca acaaacaatt gaaagttcta
   427921 aggatgttta atttagtaaa tataatagta atgctttttg tacatgtaat cgattttcag
   427981 cttcactcca aactaaactt tgattactat caatgacgtt ggcagaaacc tctttgccac
   428041 ggtgtgcagg taagcaatgc ataaatacag cagttggttt ggcttttgac attaagactg
   428101 tatcgacttg aaagtcttta aaggcaattt cacgttttat ttgttcggtt tcttgcccca
   428161 tacttgccca aacatcagtt actatcaaat caacctcttt acatgctgtt tttatatcgg
   428221 tgaataaatg aatgtggttg gcatattttt caataaaact ttgatttggt tggtaatttt
   428281 taggggcagc aatattaagt ttaaagttga aactttttgc tgcttgtata taagtgtggc
   428341 acatgttatt tccatcgcca atccaagcta cagttttatt agcaatagat ccgttgtatt
   428401 cttggtaagt catcatgtca gctaatagtt gacagggatg tgactcatca gataacgcat
   428461 taataatcgg tacagaagaa tgttctgaaa aggtctgaat atcctcatga gaagagactc
   428521 gtatcataat agcatcaacc attgaactaa tcacaattgc actgtcgatg attggttcac
   428581 cccggcctaa ttgaatatct ttatcagata agaatagggc acgaccacct agttgagtca
   428641 ttccagcttc aaaagaaaca cgcgttcgtg tagaagattt atcaaaaatc atagctaatg
   428701 ttttattttc taacgcttta ttgattttac cagatttata ttgttctttt agtttaattg
   428761 cttgtttaat gatttgagtt aagtcataat ttgataagtc attaagatta ataaagtgtt
   428821 ttatcatagg tatctcctgc ctataaagta ttgatcaagt tactaacttt atcaataaga
   428881 atatcagcat catactgatt aataatcaaa gggggaagta aacgtattgt ttgaccagta
   428941 atattaatta aaagtttgtt gtttaatgct ttttgtaaaa gagtagagca gtcttggttt
   429001 aattcaatag caatcattaa accttttgag cgaatttcaa atactttgtt tgaattttta
   429061 agtttgtttc taaaactaga tattatatat tcacccatta ctaagacatt atctaaaatg
   429121 ttatcttttt cgataatttc caatacagta agtgctgttt tacaagctag tggattacca
   429181 ccaaaggtgg aaccatgcgt accaggtgtt agtatttgtg aagcttttcc ttttgcaagg
   429241 caagcaccaa taggtatacc attaccaagt cctttagcta aagttaataa atctggcgtt
   429301 atattgttat aattatgcgc aaataattta ccagtacgac ctatgcctgt ttgtatttca
   429361 tcaagaatta ataaccaatt attattatta caaatttctt gaacttggtt caggtaattc
   429421 ttatctggaa tgataatccc gctttcaccc tgaataggtt caagcataac tgcaacaata
   429481 ttgttgttat tttcatgggc tttaattgct ttaatattat taaagtcaaa atagataaag
   429541 ttactaacta atggtgtgaa accttcttgt attttaggat ttccagtggc tgaaagtgtt
   429601 gccatagtac gtccatgaaa actttgatta gcagttaaga tggttgggtt gttaatatga
   429661 ttagcatggc catgtaagcg aacaatttta atagctgcct catttgcttc agcaccagaa
   429721 ttggcaaaaa aagctttatc catattagat aattgacata acttttcagc taaatcttct
   429781 tggtactgga tatggtacca attactggta tgtagtaaat tagcagcttg tgtttgaatt
   429841 gtttttgtaa tatcttgatg acaatgtccc agtccaacaa caccaacacc acaaagagcg
   429901 tctagatatt gttcatcttt gtcatctatt agatagcaac ccacaccttt gacaaaagtg
   429961 actttaagtg gtgtatagtt tgacattaaa taggacattg tgactatcta aaacagttaa
   430021 taaaaaagct ctaaactaag cttttattac caatcagaaa atcatttatg actggtaagt
   430081 taatggtggt gccatttcat tattaatttc atctaatttt tttttgtatc cttcataaaa
   430141 agagcctgct ggtgggttaa tccaatcttt ataagaaaaa ccattgactt gtgtatgggc
   430201 tttgaaagta ttttgtaata caattctttt agcgcttaat tcgttagaat gttgacttgt
   430261 tgcaatcatt ttgatctcct aaatatgtaa gtaagtaaac gtcagtatta tacactttaa
   430321 ataagattta aggtttttgt cttaaaagcg tataaattac cttataattt atattaaaat
   430381 tttactttaa tataaattat ttttcaaaga aattaaggag tatatatgca gttgaatatt
   430441 tctggtcatc atcttgatat taccgaagca attaaacaac attcgttaac aaaattaaac
   430501 aaaataaaga atcattttaa tcaggtaatt aacattaata tgattttaga agttaaaaaa
   430561 gatgtacaaa aagctgaggc aataatccat gttagtggtg cagatttatt tgcaaaagca
   430621 gaaagttttg atatgtataa ttctattgat caaatggtta ataaattaga tgttcaaatt
   430681 agaaaacata aagaaaaatt aaacaaccat agaaaaaaac taacaacaat ctgagtttta
   430741 tttaaagatt tatattgttt aacagatacg agcaatactg atgttagaag ttgaaaacac
   430801 ttcgtttaaa gattgtcttc agaaattaat aaagttttta gagcatttaa aatatgaaga
   430861 ggcaatctct tatcttgttg agctacaccc gattgaaatt gctcgtttat tagaaagtat
   430921 accgcctaaa gataggattc aaatttggtt aaatattgat attggaatta aaggcgatat
   430981 tattaaaaat ttaaatgaga atgttcaatc tcaattgcta agtaaaatgg atgttgttga
   431041 tattgtaaag actatagaag tcttggatat ggatgattta cctgaatcaa aaatacataa
   431101 cttattatta atattagatt ataaacataa agatcaccta aaacaaattc tatcttatcc
   431161 tgaagactct gctgctggtt tgatgaatat tgatattatc accgtacgtg gtaacgtgac
   431221 agtaggtaca gttattcgtt atttacgttt gttaaaagaa atgccgattg atactgacca
   431281 agtatttgtg gttaataaat cttatcaata cctgggctct atttatattt ctactttatt
   431341 aactaatgaa gctgaacaaa atattgatct actcataaac aaaaaatcaa aacctattct
   431401 agccaccact attgataatg aagtagccag cctgttcgaa cagaggaact taatatctgc
   431461 tcctgtggtt gatgagagta atcagcttat aggtcgtata accattgatg atgtggttga
   431521 tattattcgc gatgaagctg aacactcggt tatgtcaatg gctggtctga atgaagagga
   431581 ggatgtattt tctcctgtta tacaaagtgc taagcgtcgt agtatttggc ttggaattaa
   431641 cctaattaca gtttttattg ctgtattttt tatcggtctt tttgaagcca ctttacaagg
   431701 aaaaattaca ttagcaattt taatgccagt tgtagcgtca atgggtggta ttgctggtac
   431761 acaaacactt atcttggtaa cacgtggtat agcaacaggc agggtaacag aggctaatct
   431821 taaagtatta atgaataaag aggtggtaat tggggtttta aatggtattt tctggtcttt
   431881 aataattagc gtggtaactt atatttggtt tacagatttg atgctaagcc tagtgattgc
   431941 gttggcgatt attgttaatt taatttttgc tgctttttca ggtgcatttt taccattact
   432001 actaattaaa tttaaaattg acccagcact tgctggtggg gttattttga cgacaattac
   432061 tgatgttatt ggttttttag cttttttatc tttagcgacg ttgattgttt agtaatttag
   432121 gctttttaaa aatatcactt aattgatttt tagtttaatg gttttattat taattgagaa
   432181 aaattttact aaaatattag ggtttgagcg gtttttgacc atttctagag aaattttagt
   432241 tgtatatatt tatgggattg tttcggtatt ataggcgaga tattatctat tatatttgta
   432301 attttatacc tcttaatcat ttatgcataa ctctaattta tatctatata ataatgttga
   432361 tttatcaaaa atattggtat atctttaact tctagtctta gattagatcc taactgtaac
   432421 taatattatt attaaaaata ttgagtagaa atgttgttac tttttagcca aattctgaat
   432481 ctttcttgaa tttcatttaa cacttcttga ctatctgctt caaatctaag gaccaaacaa
   432541 ggcgtggtat tagaagggcg aattaatccc cagccattgt catagtcaac acgaatacca
   432601 tcaatagtgg taattcttgc attagggaaa tctacatttg cagctaattt attcatgaca
   432661 ttaaattgtt caccttgttg gtcaaaatga atattaattt ctggtgtatt aaaattatca
   432721 ggtaattcag aaaatatttc ggcacaagtt ttttttgttt ttgatagaat ttcaagcaac
   432781 ctagcacctg tataaagcgc atcatcaaag ccataccaac gttctttgaa gaagatatgt
   432841 ccactcatct ctccaccaag tgctgcacca gtttctttta atttagcttt aataaaacta
   432901 tgtcctgtgc gtgacataat tgcctcgcca ctatgtttga taatgtcttt ggataacagt
   432961 gatgaacact taacatcaaa aacaatcttg gcacctttat tacgcttaag aatatctctt
   433021 gaatataaga tcatttgtct atctgcccag attacatttc ctttgttgtc aatcaacccc
   433081 aatctatcac catcaccatc aaaggaaaag cccatgtctg cgcctgtatg ttttacttct
   433141 ttaataatat atttaaggtt atgaagttta gaagggtcag gatggtgatt agaaaagtta
   433201 ccatcaatca aacaaaataa ttttgttact ttaacaccta attgttcaaa tagttttggt
   433261 gcaatattgc ctgcaacacc atttcctgca tcaacaacaa tactaaatgg tttttctaat
   433321 ttaatatcat gagtaatacg cttaatataa tcttcttcaa tgttcacttt aattgaagtt
   433381 ccatgacctg aggaaaaatc accaatttga atacgttgat aaagcgcttg aatacgttca
   433441 cccgagagtg tttctcctgc aattatgatt ttaaaaccat tatattctgg tggattatgt
   433501 gaacctgtaa tcattacacc tgaagtactg gctttagtat gcgttgcaaa atatactaaa
   433561 ggagttacta ccataccaat atccacaata tgacaaccac tttttttaag gccttctgtt
   433621 aaagcttgca ttaaatcaaa actactgagt cgaccatcac gaccaataac aatattgcgc
   433681 tcatatttag aaatagattc gctaccaatt gctaaaccga gaagtttgac attttcagga
   433741 gttaaatcat ccttagcaat accacgaatg tcataagctt taaaaattga ttgtgaaata
   433801 ttcataattc aataagatag cgtacaataa agcctttatt ttaaacacaa agactaatta
   433861 agtgaaagaa cagtttaaag ttattacaat taacaatgaa attatgacac ttgaagttaa
   433921 tcgctcaagt ggttgtcatg gttgcgaagc aagtagtagt tgtggtatag ggatattgac
   433981 taatcattat tctgtgttta acaggccatg tcgagataat atttcagctg gtgattttgt
   434041 aacattagaa atttcttcaa gtgaattatt tctacgtgct tttcaacttt acatactacc
   434101 actgttatcg ttatttataa gtggagtact aggtagtatc ttatatacag ttaatgaaat
   434161 gggacaaatt gtatttgctt tgattggttt ttttatttca tttgtattta ttaaatattt
   434221 tataaagtag actctaaaga tataataatt ttgggataat tggttttttt aaaataaatt
   434281 atacattatt atgttagttc aagatattga ccctttggaa acccaagaat ggctagaagc
   434341 ttttaaatct gttgttcgta ttgaaggtga tgatcgtgtt aagtttttgt taaatcaatt
   434401 aatgaacatg gcatatcacg aagggataga tttaccaaca gatgttaata cttcttatct
   434461 caatagtatt tctaaagaaa aagaagttgt aactgatatt aataaagata ttgaggaaag
   434521 aatttcagct attgtccgtt ggaatgctat ggtaatggta gtaaaggcta atcagttgcc
   434581 gtatgatttg ggtggacata ttgcttcatt tgcatcaagt gcaactttat atgaagttgg
   434641 ttttaatcat ttttatcggg gtcctgatgc acatcagggt gcagatcttg tcttttttca
   434701 agggcatata tctccaggta tttattcccg tgcttattta gaaggacgta ttactgaaga
   434761 ccagatgctt aaatttcgtc aagaagttgg aaaggatggt ttatcttctt atcctcatcc
   434821 atggttaatg ccagattttt ggcaattccc aacagtttca atgggtttgg gtccaattat
   434881 ggcaattttt caagcacgat ttatgaaata tcttcatcac cgtgaaatta aacaaactga
   434941 caagcgtact gtttgggcat atttaggtga tggtgaaact gatgagccag aagcattagg
   435001 cgctatctca atggcaggtc gtgaaaaatt agacaatctt atttttgtta ttaattgtaa
   435061 tcttcagcgt cttgatggtc ctgtacgtgg taatggaaaa attattcaag aattagaagg
   435121 tgtatttcat ggttctggtt ggaatgtgat taaagttatt tggggtggta aatgggatga
   435181 attatttgcc aaagatactc aaggactctt aaaaaaacgc atggaagaag tggtggatgg
   435241 cgaatatcag gcttataaag ctaaagacgg cgcttatgta cgtaaacact tttttggtaa
   435301 gtatcctgaa ttattagcca tggttaaaga tatgagtgat gatgaaattt atcatcttga
   435361 tcgtggtggt catgatccct ataaggtatt tcaagtttat cattcggcta aagcatgtca
   435421 tgataaacca acagttattt tggctaaaac ggttaaaggt tatggtatgg gtgaggctgg
   435481 tgaaggacaa aacactaccc actcacaaaa aaaaatagga ctaaaacaag ttgaaacttt
   435541 tgctaaacgt tttgatgttc cagttactga agaagatgtt aaggctttaa atttttataa
   435601 gccagcactt gatagtgaag aaatggttta tatgcgcgct aaacgtaaaa aactaggagg
   435661 ttctttgcca gtacgtgcgt ttgatttaga acaaataaaa atacctaaac taaatgtatt
   435721 tgaaacgtta ttaaaatcaa gtggagaccg taaaatgtca actacaatgg tatttaaccg
   435781 agttataaca ttattagttc gtgataagca gttaggtcct aaaattgtac caattattcc
   435841 tgatgaggca cgtacttttg gtatggaggg tttgtttagg caattaggta tttattctgc
   435901 ttctgggcaa ctttatcaac ctgaagattc agataaagtt atgtggtata aggaagataa
   435961 aaaaggtcaa gttttacaag aaggaattaa tgaagcaggt gcgatctctg attggattgc
   436021 agccgccacg gcttatgcaa cgcataatac taccatgatc ccattttata tttattactc
   436081 taaatttggc ttccagcgtg taggggattt gatttgggca gctggagata tgcaggctaa
   436141 aggtttttta attggtggta ctgcaggacg tacaacactt aatggggaag gtttacagca
   436201 tcaagatggt gactctcaat tagtggcaaa taccattcca aactgtattt cttatgaccc
   436261 agcttatggt tacgaattga tggtaattat ccattctggt ctttatagaa tgtatgaaaa
   436321 acatgaaaat attttttatt acatcactgt aatgaatgag ttatatactc atccagaaat
   436381 gccaaaaaat tctgaacaag gtattattaa aggtatgtat aaattaaaaa ccattggtaa
   436441 gagtataata gaagtacaat taatgggttc tggaaccatt ttaagagagg tggaaaaagc
   436501 tgcaaaaatg ttggctgatg attggggggt gaaatcaagt atttggtcag tgacaagttt
   436561 taatgaatta acacgtgaag cacaagctat tgatagagta aatcgtttta atacaagtgg
   436621 tattacacag gtaccttata ttacaaaatg tttagaagac gctaatgggc cgataattgt
   436681 agcaactgac tacatgcgta attttgctga gcaagtacgt aagtatgttc ctaatcgata
   436741 cgaagtatta ggtacagatg gttttggtcg ttctgattca agagctgcac ttagagaatt
   436801 ttttgaagtt aatgctaaat acataactat agtggcatta aaagcgcttt cagatgaagg
   436861 tgagattgac atttcaattt ttacaaaagc gattaaaaaa tataaattta atatcagtaa
   436921 acctaatcca atgacagtat aaactagtaa aaaaagacgg aactaaacta tttaaaatta
   436981 tttgtatgac aatatttttc tcatgtgcaa gaactattca tttgggtttg taaaaattat
   437041 ttttctaata aaactttacg agataattta atacgacctc tgtctaaacc tataactttt
   437101 acatcaattt tatcaccttc tctaatatga tcttttactt tttcaacacg ttcatgagaa
   437161 atttcagaaa tatgtagtaa accatcttgg ttaggcatga tattaataaa agcaccaaac
   437221 tcaacaattt taacaacttt acctgtataa actttattca cttcaggtat agcggtcaca
   437281 tctttgacca tttgcactgc tgtatcaaag gatttttggt tattggaaaa aatattaaca
   437341 ttaccactat catctacatc aatactagca caagaagttg agatgatacc tttaatggtt
   437401 tctccacctc tgccgattaa atcacgaatc ttatcagttt taattttaat aatggtagtt
   437461 ttaggtgtat ttttgtttga cgtattaggt tcacaaataa cttggttcat ttgacctaaa
   437521 atattcaatc ttgcctcttt agcttgtttt agagcgattt ccataatttc atgggtaatg
   437581 ctctggattt taatgtccat ttgtaatgca tttactccac gtgatgtccc tgctacttta
   437641 aaatccatat cacctaagtg atcttcatca cctaaaatat cagtcaatac ggtaaatcta
   437701 tcattttctt taactaaacc catagcaatg cctgctattg gtgcttttat tggtacacct
   437761 gcatccatca atgataatga tgagccgcaa acactagcca tagaactaga accgttggat
   437821 tcggtaattt ctgagactac acgtactgtg tatgggaatt cttcaattga aggcaagcaa
   437881 gcagtgatac cacggcgtgc tagatgacca tgaccaattt cacgacgttt gattgtagct
   437941 aagcgaccag tttctcccac acaatatggc gggaagttgt aatgtaacaa gaagtaatta
   438001 ttttgacgct cgggagattc taatttttca attaactgag catcactctt agggcctaaa
   438061 gtggttacaa ctaatgcttg tgtttcacca cgagtaaata aagcagagcc atgcgtattt
   438121 tttagaatac ctgtttcaat ctttaactca cgaacagttt cattattacg accatcaata
   438181 cgagaatcat tatttaagat gcgctcacgt acagttgatt tttcaacttc tttaaagtat
   438241 ttgctaactt cttcagcaga atttccattt tcattttcat tttccaatgc ttcaattgca
   438301 gccattctga tgttatcaat tttggcatga cggtcaagtt tttcctttat ttggtaggct
   438361 ttgttaattt ctttgccaaa ttttgatttg atatcactta ataaaacttc attagttata
   438421 ggtgctatcc agtcccattt ttgcataccc acttcagtgg taaattcagc aatattggta
   438481 atggcaactt ggtattgttc atgtgcatac acaactgcac ctaacataat ttcttcagaa
   438541 agttcattag cttctgattc taccattaat actgcttcat cagtgcctgc aaccaccatg
   438601 tccaaatctg aattagtcaa ctcaatataa gttgggttaa gaatatattc accattagaa
   438661 tagccaacac gagaaccgcc aattggtcta ctaaacggaa caccagaaat acttagtgca
   438721 gcagatacac ctaacattga aataatgtct ggattaacct cagaattggc agaaacaacg
   438781 gtaataagta cttgtatctc attcatgaaa ccatttggaa atagtgggcg aatagtgcga
   438841 tcaattaatc tagatgttag agtttctttt tcactaggcc ttgcttcacg ttttagaaaa
   438901 ctgccaggaa tttttccggt tgagtaagtt ttttcaatat aatcaacaga tagaggaaaa
   438961 aaatcttgtc caggccgtgt ctctttagag ctaacaacgg ttaccaatac ttgcgtatca
   439021 tccatacttg ccagtactgc gccatgtgct tgcctagcaa tacgccctgt ttctaatgtc
   439081 actatgtgtt tacccatagt gaagcttttt gttttgatat tcatacccat gagaatctcc
   439141 aaagaaaaat taaaaaagaa gtctatggtt tgaacctaat aagctttatt tgaaatatat
   439201 ccaaaccttt aaaacaagta aaatcctttt tgcttataac gaatacattt tatgtaaaac
   439261 ttatgctcaa ttagaccata aaacttagtt attatactca ttaaatcttt gattgagaat
   439321 gaatttaata cagcttgtat tcattgtggt aatttcagaa ggggtaaaat cggaatcatg
   439381 ttaaagtggt tagaattttg tatttattgg gtaatttatt atttgaattg gttaaaggca
   439441 aataataact ttttcagtaa ataattttac tgctgtaaat agtcatgaac taaagtatca
   439501 aaagatgatt tattagattt tttaatggtt tggcaaaatt aattctaata ttctatagaa
   439561 ctgtttgtta tgctaattat agtttcttat atagaaaata cgtaaacttg aaatataatt
   439621 ccacaaccaa caaaacccat ttaggggttt atatttggat agtcgaattt aagggggtgc
   439681 ctaatagttg gtattttcta aattaagttt aattaatatt ggtttttcta ctaataatta
   439741 gttaaaattt ttgttcataa acttttctaa aatggatcac ttttatggta cttgtttagc
   439801 taatacaaac aaaaaatatt ggtgaaaaag tttgattgtt attgatgata atttgatgct
   439861 tcttttgtaa tagatacatc atgaacatga gattcgacca tacctgctga ggtaacttgt
   439921 acgaattgtg agtttgtacg cattttttct aatgtatcac aaccaatgta acccatagaa
   439981 gatttaacac caccaatcat ttggtgaatg atagggcgta tagaaccttt aaatggaaca
   440041 cgaccttcta ctccttctgg tactagttta tcggcttttg agtctgattg aaaatatcta
   440101 tcagatgaac cgtgtgcttg gttcattgcg cccaatgaac ccattccacg ataagattta
   440161 taagaacgac cttggtaaag ttcaacttcg cctggagatt cttcagtgcc tgctagcatt
   440221 gagcctaaca tgacgcagta tgcgccagca gctaatgcct ttgcaatgtc accagaataa
   440281 cgaatacccc catcagcgat tagtggtata cctgtgtctt tgagtgcatc tgccacttct
   440341 gaaatagcac tgatttgggg tatacctaca ccagcaacaa tacgagtagt acaaatacta
   440401 cctggaccaa tacctacctt tacgcaatct gcacctgctt tgattaaatc tagtgctgct
   440461 ccgcctgtgg cgatattacc agcaataata gacaagtttg gatgtttgtt tttagtttct
   440521 gcaaccctat taagtacacc ttgagagtgt ccatgagcag tgtcaataac aatgacatct
   440581 acacctgctt caataagtgc atcaatacgc ttacttgtac cagcaccaac cccaacagca
   440641 gcacctacac gtaaacgttc ttctgagtct ttacaggcat tgggaaaatc tgttgatttt
   440701 tgaatatcac ttacattaat cataccttta agattgaacg tatcatcagt tatgatgata
   440761 cgttcaatac gatgcttttg caataatgat cttactttgt ttatatttgt accttcttta
   440821 acggtaatca atttgttttg cggggtcatg acgtttttaa ctaattcgtt caaacgggtt
   440881 ttgaatctta catctctacc tgtaactaag cctttaatag tattaccttc aactacaggt
   440941 aaggcagaaa tattatattg ttgctgcatt ttaagaacat cagcaatagt tgcctttagt
   441001 gatatagtga ttggttcttt aataatacct gattcaaacc gtttgacacg gtgaacctca
   441061 ttagcctgct cctctactga tatattttta tgaattatgc caattccgcc ttcttgagca
   441121 atggcgatag ctagtttaga ttcagtgaca gtatccattg ctgctgaaag aatgggtatg
   441181 ttaagagtaa tatttttagt taattgcgtt attaggttta ctttttttgg tatgattttt
   441241 gagtattctg gtactagtaa tacgtcatca aatgtgtatg ctgtttttag taaattcatt
   441301 aatatctcct acggttaaca aaatttgaaa gaatgagacc tattattgca ccaaagaata
   441361 atactaaact acctgtaatg aaccagtttc tagaactata attctgtgtg gcagtgttgt
   441421 tattttctaa tagttgaatt tcggctttta gttgtaatat ttttgtagaa agtttttcgt
   441481 tagaatgttc aagctttagc gcatctttat agattttttc aatgtgttgt ttttcagctt
   441541 tagatttgtt cttttgtata aagagcttgg tattttgatt ttttagtatt ttaacttgtt
   441601 tttctagttc tgtatttctt ttaccttgtt taatacttag taattgatta gagttatatt
   441661 ttttcttaaa cttgtctagc tttactcttg ctggtggatt attagacaaa tatcttgata
   441721 taacccagcc tattgagtct ttatacttaa cttgagtcca gccgtcttta gtagcttgta
   441781 agatatataa ttttgctcca gaagataaag atcgtattat gttattatta aagcttttat
   441841 cttctcgcat tggaatatct acctggtcag tgatatagac aaatgattta gcgttaacaa
   441901 ttgatataag tgtgctaaat agtatgggtg ttaataacag atacttaatt aaattcataa
   441961 gctggatatc ttgttaagtt gattattaag atcatgaata gcggatagtg ttgtggctaa
   442021 tctttctttt tctatattaa tgattgtttt aggtgcacct tttatgaatt tctcattgtc
   442081 taatttactc ttaaactgac ttttcatctt ttttaacttt tttatttctt tattaaggcg
   442141 agttatttct tggcttttgt caattaatcc agccagtgga atgaagattt tcatatcatt
   442201 aaccaaggca gtagctgatt ctggtgcttg ttcggtagtt gtcagtttat taatactttc
   442261 tatttttgct agtgaattta aaatatttat gttattagtt agatattgtt catccttgga
   442321 gttaaagctt tgtacaaaac aaggtagcca ttttaaaggt gaaatattca tttcaccacg
   442381 aatttgtcga attcttaaaa taaaggtttg tagccatttc atttctgctt ctgctttagc
   442441 agatattaaa ttattaatta tttttgggta aggttgaatt attaagctcg tgttatcatg
   442501 gcctgtaatt acattacatt gttcaaagat ttcctcagta ataaacggaa tgataggatg
   442561 taataaagtc actatttcgc ttagtacttt gattaaaata gcttgtgtac ctgttttggt
   442621 tttattattt tgtaataaag acttagataa ttcaagatac caatcgcaat agtcatgcca
   442681 aataaattca tataaagttt gactcattaa atcaatacga tagtcagata aatgcttttc
   442741 aacatttatt tttgtatttt gtaaacgaga cagaatccat tcatcagctg ttgataattg
   442801 tgcattagta tcaatagttt tacctttaag attcattaat acgaaacgtg aagcattcca
   442861 aagtttgttg caaaaatttc gataaccttc aacacgcttt atatcaaatt taatatcgca
   442921 actaaaagaa gccaaggtag caaaagtgaa gcgtaatgca tcagtgccaa aagcgggaat
   442981 accattagca aattcttttc tagtttgttt tttgattttt tctgccattt taatttgcat
   443041 taatccttgt gtacgtttct caagtaagtt ttttaaggta ataccattga ttaagtcaat
   443101 tggatcaagc acattacctt tagatttgga cattttttgt ccttgtccat ccttgattaa
   443161 tccagtaata taaatatctt taaaaggtac ttctcctgta aatttaagtc caaacataat
   443221 catacgagca acccaaaaaa agataatatc aaagccagtg actagtacat tagttggata
   443281 aaaacgagat aaatcaggtg ttttttctgg ccatcctagg gtggaaaatg gccataaagc
   443341 tgaggagaac caagtatcaa gtacatcttt gtcttgaatg agtgttatgc cttctcctgc
   443401 ttgttcttgt gcttgtttaa gtgagtctgc aacaaagata ttaccttttt cgtcatacca
   443461 cgcaggaata cgatgtcccc accaaatttg gcgagagatg caccaatctt gaatattgtt
   443521 catccagtta aagtaagttt tgctccagtt ttcaggaatg aaacgaatat ccctattttt
   443581 aactgcatca atggcaggtt gaactaatgg ctttatttta acaaaccatt gatcggttaa
   443641 ataaggttca ataattgcat ttgttctatc gccacgtggt atcattaact tatgtggctc
   443701 aattttctct agtaaacctt gattatctaa atcttgaatg atttgcttac gagctttaaa
   443761 tctatccata tctgtgtagg cactattaac cccgttatta attttagcat catcagttaa
   443821 gatgttaata acatctaaat tatggcgaaa ccccacctca tagtcgttaa aatcatgggc
   443881 aggagtgatt ttaacgcatc ctgtactaaa tttcatatcg acataatcat ctttaataat
   443941 tggaattttt cggttggtta gtggtaagtc aacggtttta cctatcaaat gtgtataacg
   444001 tttatcgtta ggatgaacag caatggcact atcgcctagc atagtttcag ggcgtgtggt
   444061 tgcaataatc atcacttcat tagtattggt aacaggataa cgtatgtacc aaagtgagct
   444121 ttgctcttcg gtgttaatga cttcaagatc agatacagca gtatgtaata ttggatccca
   444181 attaaccaaa cgtttaccac gataaattaa tccttcttta aatagttgta tgaatacttt
   444241 cttaacggcg ttagataagc cattatccat ggtaaatcta tttttctccc aatctactga
   444301 aaaacctaag cgacgcattt gcgaggtgat tgtgtcacca gattgtgctt tccagtccca
   444361 aattttttga gtgaattttt cacgaccaag ctcatgacga gtcatgtctt gtgttgctaa
   444421 ttgacgttca actaccattt gtgtggcaat acctgcatgg tctgtacctg gttgccaaag
   444481 ggtttgttct ccattagcgc gatgataacg cgttaatata tccataattg tatgttgaaa
   444541 cgcatgtccc atatgtaaag aaccagtaac atttggtggt ggtagcataa tgcaatatgc
   444601 atttttgcta gtggtgtttg aattagaaga aaatagattt ttatcttccc aaagtaaact
   444661 aaattttgct tcaatttgtt ctggattgta agttttttcc attaaagtag cgagatggat
   444721 taaacttcgt tattatacta tatcatcaaa attgaattgg ttaataagtc ctatttattg
   444781 tgctgataac taatttttat tgtgatatta ataataatat gaaaagctaa gtatggatgt
   444841 aaggtataca tgtatataca tattttttaa gttggtatta agaaaaaata agaagtaatt
   444901 agaatctaat acattattat ttaggtgaat gatttataaa aatctattac ttttttgtgt
   444961 tatacatctt tctggtgtaa atataataaa ggttttttac ttaatctttg atatggggat
   445021 gatgtttaac ctgtttcata acatcaacta agtctttagc ttaagtcagt gccattttta
   445081 tatttatgtt taataaatga attgtacaat tttattgttc acatcaggta atgcatagca
   445141 aacattagaa aggtaagttc atgtcacccg tgatagtttt cattttggca gatgaggcat
   445201 tagcaatttg tttaacagca tcattcatag cattaagaat taaatcttca agcaattctt
   445261 tatcactcat tacttcatca agaattgtaa tattagtaac tatatgttca ccgtttaata
   445321 tgatttcaac gcaaccacca gcggcttttc cagtcgcaga tagatttttg atttctgatt
   445381 gtgcttgttt catattattt tgtatttgtt gggctttttt catcatgtca gtcattccag
   445441 ctttaaacat gcttaatctc cttaattgaa ttaacattaa tttttgtatc aaatattttt
   445501 tctagttttt gcacaccttc atcattcaaa aattttgttt gcatttttgt tattttctta
   445561 ctatgtgctt gagttttttt ttgtgctaat gtttgaacat ttagtttacc gaggttaatt
   445621 actaaattta atgttgaaaa tttttttcta agtgttgtta acatgctttt ttgtacataa
   445681 ttatttagta aattagtaaa ttgattatct agtgttagtg ttagtgttgt gttattaaca
   445741 ttgtcaaata atgtattttc gactaacatc tttacactac ctttaaattc tagcgatagg
   445801 ataagtgttt cccattgttg ttgattgtta atattgagta tttttggttt tgtaatatct
   445861 gatatttctt ttttttcaat tagtactggt gttttaactt tagacttgat ttttagcgtt
   445921 tttttttctg tattaggttg gttatcgcta cgaaatgcta acattctaag tagcgtcatc
   445981 tcaaatccaa tttgatcgct aggagctagc gccatgtctt tagagccatt gattgacatc
   446041 tgataaaaaa tttgtaaatc aaagtttgat atttgtttgc taagattttt agtagttctg
   446101 tcacttttag tatcaacaat ttgtgcaata gatattttat ggaacaatga acttaaatct
   446161 ttaagtgcat tgttaaggtt ttcgccacga tgagataaat ctttaataaa attaattacc
   446221 gatttagcat cttggttaaa taaatgcgta gttaaagtta taatatctcc atgatgtact
   446281 aaacctagca tagttttaat atcggcgcta gttactgtac ctttgccata agagattgat
   446341 tgatcaagta aactcagagc gtcacgcatt gagcctttgc caaaattagc aatttgacta
   446401 agggctaatt cctcatagct tagcgcttca gaatccatga taaattttag ttgacctaga
   446461 atttcatcat gggttagttg ctgtaatgtg aattgcaagc aacgtgatag aatagtcaca
   446521 ggtagttttt gtgggttagt agttgctaat aaaaatttaa cgtgttctgg tggttcttct
   446581 agggttttta aaagggcgtt aaaactacta ttagagagca tatgtacttc atcgataaga
   446641 taaattttat aacgattttt gcttggcatg tattgcgtat tttctaaaat agaacgcata
   446701 ttatccaccc ctgtgtgtga ggcagcatca agttcaatta aatcaattga ttgaccttta
   446761 tcaatctcaa tgcaagtaga acacttgcca cacggggttg agctaactcc tttttcacag
   446821 ttaatagatt tggcaaaaat tctagcaata ctagttttac caacaccccg tgttcctgtg
   446881 aatagaaaac cgtgatgcac attattagca ttaagtgcat taattaaggt ttttttggta
   446941 ttcgtttgac ctactaattc agtaaaagaa tgtgggcgat attttctagc taaaacttga
   447001 tagtgtttac tcatcaaaat aggattgatt atattaaaaa tgatagcacc aagaatatca
   447061 tccaacacat agaaaattat taccgttgct tctttccaga tctggcggag ttcataacca
   447121 tttattgttg gtacaacctt gatactatca agtagctatt ttacatttag tttagtttta
   447181 ttattagcta attctaaacg ttcttgagtt ccagcatttc gttaatagat agcgtaatat
   447241 cccgcactaa tttgatttag caatggctgt ttttattgct tttaaaagtg ctattttttt
   447301 caaataaata aggtttaaat agtgcagatt ggtaaacagc aatgccagaa aaagcatagg
   447361 ttttttgttt acaagggtta actgagtgtt atttgatgaa aaaacatttt tgattgtggc
   447421 tatgattatc aattaataga aaatgaacta gtaaacttat tgtaagtatt agctttgata
   447481 aattatcatt acaaagcatg ccactgttaa tgacaatgaa aggttcattt cctaacatag
   447541 gcaattcttt tataataaat atctgcaatt tctaataatc ttttttcatt gctatagtga
   447601 agattgatac caaattttat gccattatca gtataagact taattttggt tacttaaata
   447661 tgaaatgtta atgactattt tattgatact agtatgtttt aagacattaa ttgaataatt
   447721 caattaatgc caaaccttag atgctttaat taaggaggtt tagtgtattt tagttagtgg
   447781 tatcccatac atctgcctcg gtttattgct aggattgtgc caaatataag acttctttaa
   447841 gcgctgtaaa ctttaggtat ttatttgctg tttatcatac gtattattta accaataatt
   447901 gtaccattta aataatagtt gattattgtc tttaattgac atacgcttaa agatacatat
   447961 atatttctag ataacattta taatctacat tagtttaaat tgcttattaa attgagtagt
   448021 tgtttgttgt atttgttaaa tgttagattt tgaggggtga atagcttata ttttgataag
   448081 ttcataaaat ggtcgtcttg tataaattaa tatttaattt ccattaaaac atacagaaaa
   448141 gtgattaaac taaatcctag ttgatattga gctctaaaat aacgacgaaa actagcatca
   448201 ttatttgcat atgtgagtta aaaatcttga tgatcaaaaa aaatttctaa gccaaatatg
   448261 caacatattt aggtattcat catacattct ttaaactttg gtagtaatca taaacacggc
   448321 tccaaacgtt accaatatga ccattattaa ttaacttatt atcaactttg gttattggca
   448381 taatttcgcg tgtggaactg gaaatccaca actcatctgc agtgtttagt tcatcaattg
   448441 agaatgaggt ttcttgaata gagatatgat acgcttttgc actttctaac actaaatcac
   448501 gagtaatgcc agatagaatg tgaacattag ttggatgggt atatagggtg ttatttttta
   448561 tcataaaaac attagaagtt gcgccttcag tcacttgagt gttttgataa agaataatct
   448621 cttcaacatt tttttctttt gcttgttgtg aatacataac attggctaaa agagaggtgg
   448681 atttaatatc acatcgactc caacgaatat ctggttgtgt aatggctgaa aatcctgttc
   448741 taagtgtttc cttggtttta gttaacaaaa tgttagattc gatatagaca gttggtgtta
   448801 aattactaaa actatgctgg cgtttgttac ttataccccg acttatttgt aaataaattg
   448861 attgttcttg attgttgtaa aattttagaa gtttattgag aatactgtcc cacttttttg
   448921 gactatatgg attttttatt ttgatcgaat caagacttgt ttgtaaacgc aataaatgtt
   448981 catcaagacg gaatatttta ccgttgtaaa taggaattac ttcatatact ccatcaccaa
   449041 acaaaaaacc tctatccatc acagaaatat gtgcttggtt ttttttaata aattctccgt
   449101 ttaaaaatac cactaaaatc caatagtttc aagcatgcgt gaaaaaaaac ttgcttgttg
   449161 tgcatgttca agtgcaataa gtggaatact agccatggtt ttacctttaa actgaatgag
   449221 aagttttcca acaacatcac ctttattaat aggtgctgat aaggctgtgt caagctggat
   449281 aacttggtct gaaaatttga actggccacg tgctagagta aaactaatta tttttgatgt
   449341 accaaccttt aacatgtttt tagttgagtt agcgataggt aattcttttt ttatatttct
   449401 aatggtctta gtttcaaaaa aacgaaagcc gtaatcaaga attttttgtg tttgtgaagt
   449461 tctgtcgttg acactactag accctagaac aacagaaatc aagcgcatac caagacgctt
   449521 agcactagct actagattgt atcctgcttt tttagtaaat ccagtcttaa gtccatctac
   449581 tgtatgatca ttccatagta acttattacg gttgtattgt ttaataccgt ggtaagtaaa
   449641 ttctttttct gaataccata ggtaaaattg aggaaagtct ttaattattg ctgttgctag
   449701 taatactata tcagcagcag tagtgtattg attattgtct ggtaaaccag aagcgtttct
   449761 aaactgagaa ttattcatgc caagtttgcg tgcatattta ttcatataag tggtaaatgt
   449821 gctttcatct cctgcaatat gttcagctaa ggcaacagca gagtcattgc cagattgaat
   449881 aatcatgcct ttaagtaaag tttcaagctt catagttttt cctacttcta caaaactttt
   449941 tgaaccacct gttttccatg cttttttact gatacgtact tcgtcctcta atttgatacg
   450001 atcattacta atgagttgaa aaatgacata ggctgtcatt agtttagtta aacttgctgg
   450061 tgctcgtttg tagtgttgtt tgttactagc aataacttta ccagaattgt aatcaacaat
   450121 actataagca acagcagata tttctggcgc tttaggggta atgaaaattg ctgcttggat
   450181 atttaaggta aatgagcata taagaatagt taagaatttg ataaataatt tgttttgcat
   450241 aaaatattag ttatttagtt aattaaatac ttgttttaac ttgctttaga gttgataaag
   450301 catatctatt attgtgatta taatatggta gtacttaaaa attataaaaa gtaagcaaag
   450361 ttttattgat tgactatctt tagtaggtta atgaattcca atttggtttt atttttaata
   450421 tcttgatgaa tattcaaatc cttattccgc caatactgga tattttttct atgtatatta
   450481 gtatttaatt tcagcacgtc taagtgttgc taagttattt ttacaaaaca atcaatgtta
   450541 tctttaatgc gttcctaaat aataaacaaa cctttatatt tgtcccaaga catgattttt
   450601 tcttttttct tttatctgca agtattcatt taacttatta aaaagtaaag agtaatttat
   450661 ctttattaga tttgtgattt ttcactatta tttttaataa gatcatgggt tacttgaaaa
   450721 ttaattttta gtaaaaacta agttaggaaa tcaaggaagc aagagtatgt acattatttt
   450781 tgtaagtaac ttggtgtttt atgtttacga attgccatga taatgccaaa actagacatt
   450841 aaagtaatga ttgatgatcc gccataacta atcattggta atggtacgcc tactacaggt
   450901 aatagtccag ataccatgcc aacattaaca aaaatataag taaaaaagac aaaagtcaaa
   450961 ctcaagccta ataattttga aaaattatcc tccgattgaa aagaaattat tagtagtcgg
   451021 taaataatta acccatacaa ggtaaataaa aatataattc ctataaaccc tagttcttca
   451081 gcaataacag caaagataaa gtcagttgta tgctcaggta aaaaattaag atgagattga
   451141 gaaccttgtc ctaagccttt accaattaaa ccaccagagc caattgcaat ttttgattgc
   451201 aagatatgat agccagaacc taacgggtca gaacttgggt caaataaggt cataatacgt
   451261 tctttttgat aacctattaa taggtaattc cataagacgt agacgcctaa catagtgatt
   451321 gatgaaatca aagtaaaatt tagccaatta tttttaacaa tttgaatgcg gacaccagaa
   451381 aaaaataata cataaaaacc agatgcagca attaatagtg aagtacctaa atctggttgt
   451441 ttagcgatga gtattacaat taaaataata gcaacaatgg atagaaaaat tggtagtagt
   451501 tttggtaaaa atgttttctc acttaaaatt gaagcaatag caatagggac gataactttc
   451561 ataatttcag aaggttggaa acgtataaaa ccaaaattaa gccaacgttg agcgccccca
   451621 ctatttgaac caaaaaataa gacgagaaat agcaaaaata taccaaacaa cattaaataa
   451681 ggagagaaac gtttaagttc gtaaggtggt atttgggcaa taattaacat tgcacaaatt
   451741 gccagtgcaa agtggaaggc ttgcttatac atagtttgca tagaaccttc tgaagctgaa
   451801 taaagcacaa taagtccaaa cccactaagt gctataatta ataaaaataa aggagtatct
   451861 atcttgaaat aatgccaata ataacgtatt tgtgcaacac ttaataattt cataataata
   451921 acaaaccaac tgatctagca tcagatagta gtaaattaaa acttctacaa gctgatttat
   451981 tattcataat ttcagtatta atacccattt gacgaatagc tatctgttgt tttggatgta
   452041 aaaatttatg tgttaagcct gtaccaataa ttaataaatt aatactatct tgattggata
   452101 gagggaataa cgaaatttta ttaatatcat tgagatgatt gatattaatt tcacaatagt
   452161 aactacaaga aataaaacaa ggtattttaa gctgtatatg tgttaattta acatggtatt
   452221 ctttgacgga aataatactg ttataatctg cctcttgttg gttaaattcc atggtattac
   452281 agcgattatt tgatgaataa aagcacatta taacagtgta aaattaattc tattttctat
   452341 tatcagagga acagatgtca gattcaagta atatagatat atataatgca gatttatcca
   452401 gtggtgtcac tgcttttgat actaagaatt ttaccatggc atatcaatta ttagctccgc
   452461 tggctacaaa aggtaatgct gaggccttat ggcgtgttgg catgatgcaa atgaacggtt
   452521 taggtatggt cgaaaaccag cctttagggt ttgaaaattt tttacaagca gcaggaaaag
   452581 gacatgcatt tgctcatcat atgctagggg tggcatatat gactggagag ggtgtagaaa
   452641 aagatattat acagtctatt gagtggttta aaaaaggtgc taaatttggt atttctggtc
   452701 caatgtacac actaggtatg ttgtttgaag atggtaaaga agttaaacaa gatttagaaa
   452761 aagcacaatt ttggttcgac aaagccgata gagtaagcct ttaacattaa aaaataatga
   452821 taaaatcaag atttgcccca tccccaacag gctatttaca tattgggggt gctagaactg
   452881 cattcttcgc ttggatttgg gctaaaaagc aacatggtaa atttgtatta cgtattgaaa
   452941 atacagattt agaacgttca actcaagcat cagttgatgc aattttacaa ggcattgatt
   453001 ggcttggact taattatgat gaaggtcctt tgtaccaaac ggatcgtttt gacaggtata
   453061 aacaaattat ccagcaacta ttagatgaaa aaaaagctta ttattgtgaa tgttctaaga
   453121 agcgtttaca aatattgcgt gaagagttaa caaaacaagg taaaaaagct aaatatgatg
   453181 gttgttgtcg gaataaaaat ctacatactg gtgttgtacg ttttaataat ccaaaagaag
   453241 gaatagtggt ttttaatgat gtagtcaaag gaaaaatttc aattaataat caagaattgg
   453301 atgatttaat tattgctcgc agcgataaca caccaactta caatcttact gtggtagttg
   453361 atgatcatga tatgaaaatt aatatcatta ttcgcggtga tgatcatatt aacaatacac
   453421 ctaaacaaat taacctttat caagcattag gttggcattt accagaattt gcacacttac
   453481 ctatgattct aggtaatgat ggtatacgtc tttcaaaacg acatggtgct gtgagtatta
   453541 tggcataccg agatgcagga tttctacctg aagctttact taattattta tcccgtttgg
   453601 gctggtctta tggtaaccaa gaaatatttt ctataaataa aattgttcag ctatttgaat
   453661 taaaaaatat caataaagcg tctgcaagtt ttaatcaaga taagctgttg tggttcaacc
   453721 aagaaaccat taaaagctct agtgttaaga atttacttag taacctgact tggcatttac
   453781 aaaatcaaga aattataatt aaagatacac ctaatattga aatagtagtt cgatacttac
   453841 aagatagatg taaaactttg gttaacatgg caggtgagtt aaaaatgttt tatcaagatt
   453901 ttgatacttt tgatgaaaaa cttgctaaaa aattttttaa agataaaaca ccccttaaac
   453961 gattatttgt agaattagaa atgctaaaca cctggaaagc tgataatatt aaacaagttg
   454021 ttaaacaagt atgctttgaa ctcaatatcg gctttggaag agtaggtcag ccttttaggc
   454081 ttgcgctaag tggtgatggt aatgcaggca gtattgatat tgtagctgag ttggttggta
   454141 agaataaagc gttattacgt ttaaaaatgg cgattgattt ctaataaata cttataaata
   454201 tgatagattt atcactattt aaagcacaat atcaatcatt acaggattta atcaaggaag
   454261 attttttaaa tagtccagag acagctcaag cacttatttt atatagaagt gatggaattg
   454321 atcaattact aaaggatatt tggcaaagtt ttaatatttc tgatcaattg tgtttagtgg
   454381 cggttggagg ctatggtagg aaagaattgc atccgtattc agatatagat ttattaattt
   454441 taattcctga tggttctcat aatacttatc aacaagatat tgctagtttt ttgacatttt
   454501 tatgggatgt aaatttggaa gtaggacatg caactcgaga tttaaaagat tgtattagtg
   454561 taattgatga tcttagtgtg gtgactaatt tattagaatc tcgagttatt ctaggtaaag
   454621 tatctttatt ttataagatg aaagctgtga ttaaatctag cgtttggtca agtcaatcat
   454681 ttttagttgg aaagaaaaaa gaacagcata atcgtcatca aaacccatct aatactgctt
   454741 gtaatttaga gcctaatatt aaacaaagct ctggaggtct tagagatatt caaacggttg
   454801 tttgggtagt aaaatggtat ttttgtgtta atactttgtt tgaattggtc gataagcaat
   454861 atttaacaat ttctgaatat gaattattaa acacatcaca actattttta ttcaaagtca
   454921 gatttgcatt acatattatt gctaatcgac gtgaagacag acttatattc caatatcaaa
   454981 aatctgtagc aattatatta ggttatgttg atggggattt tttagcagtt gagactttca
   455041 tgaaagatta ttatcaaaca gtgactaagg tctctcgtct taatgatatt ttgttgcaat
   455101 tattagaaga tgaaatttta aacacacagt atttaaatag tcgttttatg gttagtcatg
   455161 gttacattca ttcaattgat gagcggattt ttattcaaat accgtctact tttattgaaa
   455221 tatttttact tattgctaag cataattatg tatgtggtat tagtgcaaaa acgcttagac
   455281 aaatgcaaac tagtatcaat ttaattgatt gtgactatta taaaaggcgc aataataatc
   455341 gattatttat tgaattatta cagcaaaatc aaggggttaa taaggcgtta aaacttatga
   455401 atcgttatgg tattttagag cgctatattc ctgcttttgg tcagattatg gggttgatgc
   455461 aatatgattt atttcatgca tatacagtag atcaacatac gttgtttgtg attcgtaatt
   455521 tgaggcgttt ttttgtgtct gagtttgcta aggaatttat actttgtagt gagatagcag
   455581 taggtattca aaaaccagaa ttgttattat tagcagggct ttttcatgat attgctaaag
   455641 gtagaggtag agagcatgct cagttaggtg caattgatgt acgtaaattt tgtcaatatc
   455701 atcaattaaa aacaaacgat attgatttag tttcacaatt agttgaaaaa catttactca
   455761 tgtcaatggt tgcacaaaaa caagatattg gtgattttga ggtaattaaa tattttgctg
   455821 agcaagtgag tacagttgaa ttcttagaat ttttatactt attaacagta gctgatattc
   455881 gtgcaacaaa agataattta tggaatagct ggaaagattc tttgctgaaa aaactatttt
   455941 acaatactaa aaaatactta gaaaatagta atggtcaacg tccaagtgta gatcaaagag
   456001 tgcaagatat caaacaaact attattaata actctattat tcaaggttat ccaataagtg
   456061 aggttgaaaa aatattatca actttaccta aggattatta tttacgttat gatatgagtg
   456121 atgttctatg gcatttgaat tttactacta aaataactgt agataagatt attgttagct
   456181 ctagaatttc acaatataac gtagttgata ttcttatttt atgtaatgat tttaagggtt
   456241 tattctttaa attaattagt attcttgaaa gattgggact tgatattgtg gatgctaaaa
   456301 ttttaaccac taagaataat aaagtctata acacaattag tgttttgcaa gatgaagcac
   456361 ttgagcatat taatataaat caaagaatca aaaatgagtt ggataattta gatgtgagcg
   456421 taagaataac tcatgatata tacatgtatc aatattttga tcataaagtg aaagttagtt
   456481 ttagtttaaa tgaacaatgg aacctaactc aattagaaat taacgcgctt aacaagcaag
   456541 gcgtactttc taatattgct tacgtatttt ctgaattaaa tatcttatta attaatgcta
   456601 gaattgcaac tatgggagaa agagttgagg atgtattttt tattagcaat gctaaaaatg
   456661 aaccattgag tatggcagaa aaattaattc taaaagagag tttagaggaa aaattgtaaa
   456721 aaagaattat gcgagttaaa taatgatata attttatgca gttatcaagt tctgctgttt
   456781 tttaatttca gattaatata aaaatatgaa cgataaaatt aaaatagtag ttgatgcctc
   456841 ttttgaagca gaagttgtta actcatcaca agtggtatta gtagattttt gggcacagtg
   456901 gtgtggaccg tgcaagacac taatgcctgt gttagataaa attgctgatg aatatgatgg
   456961 tagggtgctt atcgctaaaa ttaatataga tgagaatcaa aaaataccat caaagtatgg
   457021 aattcgtggc attccaacta tgttgttatt ttttgagggt gttgttcaag caactaaaat
   457081 gggtgcactt tcaaaagcag aacttagtgc atttatcgac gctaatattt aaagactaaa
   457141 taactgatta tttttctctt aagtagttag tttaacaaag ttttatagta ctttagatac
   457201 gcatctctag ttaagtaaaa atacttaacc ttaatatgga cacattcatg aaattatcag
   457261 aactaaaaaa atttagccca gagaagttac tagaactggc acaatcttta ggtgcagaaa
   457321 atatttctag agctaaaaaa caaaccttaa tttttattat tcttaaagcc aaagcagcta
   457381 atgatgagga agttttaggt gatggtgttt tggatgtgtt gcaagatggt tatggttttt
   457441 taagatcaag tgatgattct tatacctcag gtgcagatga tatttatatt tcacctaatc
   457501 aaattagacg ttttaattta tcgactggtg atttggttgc ggggaaaatt agagcaccta
   457561 aaaaaggtga aaagtatttt gctttaatta aggtatcaga agtgaatagt gaagatccag
   457621 ataatgttag aaataggatt ccatttgcct cactaacacc tattcatcct aatgaaagga
   457681 ttaatttaga agttggcaat ggtggtaccg aggatattac tgctagagta attgatcttg
   457741 ttgcaccatt tggaaaaggt caaagaggtt tattggttgc gccacctaag gcaggtaaaa
   457801 ctatgattat gcaaaatatt gctacgtcta tttcggttaa ccatccagaa tgtgaactta
   457861 ttgtgctttt aatcgatgag cgtcctgaag aggtgacaga aatggctcgt actgttcgtg
   457921 gagaggtaat tgcttcaacg tttgatgaac cagcaaaacg tcatgtccaa gttgctgaaa
   457981 tggttatcca aaaaacaaaa cgacgttcag aacaaggcaa agatgtgata attttattag
   458041 actcaattac acgtttggca cgtgcttata atacaattgc tccttcatca ggtaaagttc
   458101 taacaggggg ggttgatgct aatgcgctac aacgtcctaa gcgttttttt ggagcggcta
   458161 gaaatattga aaatggaggt agtattacta ttattgctac tgcattgatt gacactggtt
   458221 caaaaatgga tgaagttatt tatcaagaat ttaaaggtac tggtaatatg gagcttcatt
   458281 tagagaaacg cttaagtgag aaacgaattt tcccagcaat taacattaat gcttctggta
   458341 cacgtcgtga agaattaatt actgatgaaa aagaattaca aaaaatatgg attttgcgca
   458401 agattttgca tccaatggat actgttgaag cagctgaatt cttaattaat cgtttaaagt
   458461 tgaccaaaac taatgacgaa ttttttgctt taatgtcgca aaagaagtaa taaattgatt
   458521 taaaaaaacc attgtttaat ttaatcattc cgagtgtttg caccttaagc atacctaagg
   458581 tatggaacct ttattatagc aattaaagcc tttaaattac aaaatagcat tctagctaga
   458641 tatttaatgc gtaatacatt ggtgattttg agtgcagtgt ttattgtgat tagtttagtg
   458701 gtttttggta atcagttagt agtagtggtt aaagagagtc tagaagaagg tatacctgtt
   458761 aaagacttat taccactagt tggttttaat atgattagag atattgtacc aattttgtct
   458821 ttatctttat tattggctat tattttgagt attaacaagt tgtacaaaaa ctcagaggct
   458881 gtcataatga actcattagg tttgaataat aaacatttta tggtattcat tcaaccactt
   458941 gttattgtta ttgttattgt tattgttatt ttaacgacag ttgtagtacc ttggtctaag
   459001 cagcaaaaag acttgattat aaatcacagt aaaaatatat ctaaattttc ttttattaaa
   459061 gaaagagaat ttcaagagtt taaaaatggt gatattattt tttttgcatc aaaagtaagt
   459121 aattttaata attctaaaga acaaaatatg gaagggattt ttatttacac ttttattaat
   459181 aatgagccgg ttataatatt agcgaaacag gctaaaaaat acactaattt aaacactaat
   459241 agcgtgtatt tacgtcttaa aaatggtacg aattatcacg gatttatttt agatacaaag
   459301 aaaaaaatat taaattttaa tttatatgat atacaaatta ttgacggaaa tatgaaaaaa
   459361 ttaattagca aggttattaa agtagaatca aaatcaacat ttgaattgtt tttttctaga
   459421 aaacttacag aaatagcaga gtttcaatgg agaatatctc agcctttgag tattttaata
   459481 ttatcagcgc ttggtgtatt gcttggaaga acttcccaaa atggaggtag aaatttaggc
   459541 gtattaattg gtgttgttgt gtttatttta tataataatg ctttgctaat ttccaaatca
   459601 gtcttagaac ggggggagtc tttaccaatt attggactgt ggtgggtgca tttagttatg
   459661 ttgttactaa tttttatttt ttattcaatt aggaatagaa tatttaccaa ttttttttga
   459721 cactatctta atgaaatata attcaataaa attaccaata ataaaaatta ttatatttat
   459781 tatttttagt taggtttttt ataaagagtg ctatactttt tgacgcgtaa aataaccatg
   459841 ttttttaaag gaaaaatttt aatgtcatct caacctaata aaaatttaaa ggtttttgat
   459901 aatcctaata ttgaacgtaa ttttattatt caaattaaca tgccagagtt tacgtgtcta
   459961 tgccctaaaa caggacaacc tgattttgct acattgtatc ttgaatatat tgccgataaa
   460021 gtatgtatag aattaaaatc attaaaaatg tatatttggt cgtatcgaag taagggtgaa
   460081 tttcatgagg cagtcactaa taaaattctt gatgatttga ttcaaataag taatccaaga
   460141 tttatgcgct taaaagcaat tttcaatgtt cgtggtggta tttatacaac tataattgct
   460201 gaataccagc aaaaaaactg gacattcaaa accaaaattg atttgcagta tcaaggctag
   460261 tattttttat gaaagtcatt cgtcagagtg ttaagtttga tagaagtctt ctagataaag
   460321 atgctttaaa ggttattaat attataaata aagctgggtt taaagcctat ttagtaggag
   460381 gttgtgttag agattttctt ttaagtttaa ccccaaaaga ttttgacatt gcaaccaacg
   460441 ccaaaccaga acaagtacat aaattattta aacgttcacg tttaattggc aggcgattcc
   460501 gcttggtaca tgttatgttt tcagcgcgta aatttattga agtggctacc tttagatcag
   460561 gaaaagtaca agtggctaac aacggggttg ttatgcgtga taactgttat ggtaatattg
   460621 aagatgatgt tgtacgtaga gatttgagta ttaacgcact ttattacgac attgaaacac
   460681 aagaagttat tgattatgtg ggcgggcttc aagatataag agtacaagag ttacatgtta
   460741 ttggaaaccc aaaaaaaaga tttgagcaag atccggtacg tatgattaga gttattagat
   460801 ttcaaactaa attagatttt catttaagta atgagattaa gtcggctatt tttgagcaag
   460861 cgccacttct tggtaatatt tctacaatac gcttatatga agagtgtatt aaattattcc
   460921 ataatgaata tgggtttaaa atatatcaac gcttagagga gtatggtttg tttaaatatt
   460981 tatttaaaca aactcataag aatgaattta ttaaaaaagc tttattaaat acatcagata
   461041 gaattaaaag aaaccaatct gtaacacctg tttttttatt tgctgtattt ttatggcagg
   461101 ctcaaaatga gcgttttttt gtgattaaaa agaaacaatg ttctacatct ttagccatga
   461161 gtcaagcttc agaagaagtt attattgaac aaattaaaca agtttcgtta ccaagatggc
   461221 ttagtagtag aattaaagat atctggatga tacaaccaaa actagaaagt atgaatccta
   461281 aaaaagtcaa agaattgtta aaaaatccac gttttagaat ggcgtatgat tttttattac
   461341 tacgctctat aagtatcaat cctgaattag ctaaggtagc taaattttgg cataaaactc
   461401 aacaattaaa tcagtcttaa tttacaggtt atttaagtag aattaaccta tgtttatcag
   461461 aatgttactt atgccagaag taacgcagat atttaaaagt taaaaactta gaatttgaca
   461521 cctattaact aaatttactt cttcttttgt atctatttaa aagattatga gtcatattta
   461581 taaagattga tagtttatat aggtagatag gtgtattaga atagtactta gtaatattta
   461641 aatgtattat tcacacttta taagaaagaa tatcaaaatt tattattgtg ttatttttaa
   461701 ctaaactgtt actatgctta aaagaatatt tataacaaaa ataatggata aaataataag
   461761 taaatcggat aacgaggaaa aaatataaga tgtcagaaaa atttaatttt aaccaaggtt
   461821 taattgattt agaaaaaatt gtaaaagcca tggaatctgg cgatttaagt ctcgaagatt
   461881 cgcttaatca tttttctaaa ggtgttgaat taactaaaca atgtcaaagt gcactcaata
   461941 aggcagaaca aaaaatttcc atgttaactg aacaagacaa ctatacgaac gaaaaaccac
   462001 taaagagatt ataatatttt gtattatact aagtgttaaa cattacatta agacttttta
   462061 gtaatggatt ttaatgctta catcacaagg gttaatacta aattagagaa atatttacca
   462121 gtgcagggtt atttgactaa agcaatgcgt tatagcacat taaccaatgg taaacgtttt
   462181 aggcctattc ttacttattc tgttgctaat atttttagta cacatttgga tttagttgat
   462241 tctagtagtt gtgctattga atttatccat gcatattctc taattcatga tgatttaccg
   462301 gctatggatg atgatgatat acgccacaat caaccaactt gtcataagct ttttggagag
   462361 gctcaagcaa ttttagtagg tgatggtttg caaacattgg catttaaggt gttggttaat
   462421 gataatttga ttggttctga tacaaaaatt gagttaataa agtctttaac gcatgcttca
   462481 tttgaaatgg cagaaggtca agcgattgat ttgtcgatta ttgcaaaaca agttaacatt
   462541 acaacattag aaactatgca ccgaaaaaaa acaggagcat tattaaattg tgcagttaac
   462601 ctaggtgcaa ttgtttctaa aaattgtaac aataaggatc agactatttt aaatattttt
   462661 tctaaagata tcggtttggc atatcagatt caagatgacg ttcttgatat tgaaacacct
   462721 gatgagttat taggtaaaaa acaatattct gatgagtata aaaacaagcc tacctatccg
   462781 tccttattgg gattggataa atcaagactt gtttataagg atttatacga aaaagctatt
   462841 gatgagatag ctttattaag cgtagatgca gtagaattac aacaattaac aattaaattg
   462901 caagaaagat tgttttaaaa ctgaattaga atactacccc aactaaaacc tgcaccaata
   462961 ccttcaaata ataaatggtc acctctttta atacggccat ctctaactgc tgtatctagt
   463021 gctaatggta tagaggcggc agaagtattg ccatgatttt caagagtaac aattacttta
   463081 ttcattggag ttttgatgcg tttagcaaca gcagatataa tacgaatatt agcttgatgt
   463141 ggtactatcc aatctaattt atttgaattt aaattagttt ctttaagtgt tttttctgct
   463201 aaagaagata agcgattaac ggcaatttta aaaacttcat taccagacat ttcaataaaa
   463261 cccacttcat taatgtaatt attactaact tggagtgaag acaaataatt tccatcactg
   463321 aatagttttg agtatagaat accggtatta tcgctgccac ttaatactac agcaccagca
   463381 ccatcgccaa ataaaactgc agtagaacgg tcattccaat taacaattct tgataaagtt
   463441 tcactaccaa caactaatac tttattagca gcagaagctt tgatatattg ctcagctgtg
   463501 gtcagtgcaa agataaagcc tgcacaaact gattgtaaat caaatgcagg gcatgaggca
   463561 ccaattgcgg tttgtaatat agttgctgtt gcaggaaaaa ttttatcagc tgtggtggtt
   463621 gctaaaataa ttaaatctaa atctttgaca ttaataccag ccatttcaag cgcacgatta
   463681 gctgcttttt cagctaaatc acaagttgtt tcattagtca ctttatgtct ttgtttaata
   463741 cctgtacgtg caacaatcca ctcatttgtt gtgttaatgg tttttgataa atcatcattg
   463801 gtaattacgg taggtggtaa gtaactaccc gtaccaatga ttcttgcaaa tttactcatt
   463861 atgttctaat tcttttgaaa tttgaagtga tattttgtcg ctgattttag catgagcttc
   463921 aatataagcc tcagtaattg ctgttaaaaa tgaatcaatg tttgcactac catgactttt
   463981 aacaacaata ccacgaagtc ctaacaagga tgcaccattg tatttatcag gattaagact
   464041 agatttaaaa tctttaagta cgggtattgc gattaaagaa actaatttgg ttaataagtt
   464101 tctagtaaat gcttgtttta ggtaatgttc catcattgat gctacacctt cactggcttt
   464161 taacgcaata ttaccttcaa aaccatcaca aacaattaag tctacgatac ccttatagat
   464221 atcattacct tcaacaaatc ctacataatt taaattagag gcttttaata aagtggcagc
   464281 tttcctaatc ttttcactgc ccttcatatc ctcttctcca atattaagaa gaccaatggt
   464341 gggtgattca atattttcag tatgtttaac agcaattgaa cccatcgttg caaattcaac
   464401 taaagcttta ggctttgaat caacattagc tcctaaatct agcatgtgtg tatgtccagt
   464461 tatggttggc atacgaccca taatagcagg acggtcaata cctttaatgg ttcttagtac
   464521 aaagcgagaa atagccataa gtgcaccagt attacctgca ctaacacagg catctgcttt
   464581 gaatgtttta actagattaa ttgcaatacg catagaagaa tctttctttt ttcgtaatgc
   464641 aattgctgga gattcattca ttaatacaac ttcacttgca tgaataattg tgtatcttga
   464701 attaagcgta tttgatggat atttgcctaa ttcagttgtg atgctaggtt cattaccgac
   464761 aaagtataaa tgtaaatctt ggaatatatt taatgcttta atacctgcta caatagtaac
   464821 aggtatgcca taatctcctc ctgaggcatc aattgatacc tttattgcca cagggtttaa
   464881 gcatttattt tttgaatgtt ttgtactttg ttgattattt ttttaccatg gtaaaaacca
   464941 tcagttgtga tgtgatgacg taagtgaatt tcacctgttt cttgatcttc tgataatgta
   465001 gattttacta gtgcattatg tgagcgacgc atacctcttt ttgatggggt ttttctactt
   465061 ttttgtacgg ccattttttt actccttagg ttttgtttta atcttttaat tgttttaatg
   465121 ttgcaaaagg atgatattta tcttgactat ttatccattc tttatcttgg tacgattgac
   465181 acttgtatgg atgcatcgga ctcattggaa tggatattaa tagctcatct gttataaatt
   465241 caatggttga aaatgcttta tcagcattaa gaattgtttc aaaacttgaa tccaactttt
   465301 ctttctgttg ttcatttttc agaaatccaa gtttaaaact aggacttaaa tgaatattta
   465361 cctcatttaa acagcgttgg caatcaacga ttgcacttaa ttgaattgaa cctttaatac
   465421 aaggaactac attattttta atgtaaaaac ttaactcaac ttttacttta tcatcaatat
   465481 tgctaagtag tttttttatt ctaggaaaat ctttcacttg atatgtatgt gaaaaattca
   465541 accccttttt agcaaaacta aataatttta taatatctgg tattccttgc attaaccttt
   465601 atcaaaaaat caacctgata attttatcag aaaagaatca ataacttgtt ctttatagaa
   465661 taaatattta acaaattagc tagtttagtt gtattttttt taaaggcatg ataattaatt
   465721 gtatctaata gattattgta ataagataat tattttttga ttaaaagtat ctactcctaa
   465781 gtactggggt ataacaaagt tgaattaaaa attcttactt tgtttttgag tccaatttct
   465841 aataatttgc gtcaattttt tagtagattt ttcttttatc ttaattggtt tgccaataat
   465901 tacagtaata gtaccagcat gttttatgaa actacccttg ggccaaattg taccagcatt
   465961 atgataaaca ggtatgatgt cacaagatgc tttcttagcg agagctatag caccattttg
   466021 atattttcct agttttttat agggttgtcg agtcccttct gggaagatca ccacaaaaat
   466081 accatttttt aatcgatttt ctccttgttt tataattgtt tttaatgctt ttaatttctt
   466141 tccacgatta ataacaatag gcttgagtag catcaaaccc caaccaaaaa atggtatcca
   466201 taataaaatt ttcttaagca cccaagtttg tggtggaaat atttgttgaa atccaagtgt
   466261 ctcccaggta gattgatggt tagaaacgat tacacaaggt ctaggaggaa tattttcttt
   466321 gccgatcact tggagcttaa tattaagtat atattccaac caccacaagc aaaacattga
   466381 ccatttagat aaaattatgt agcgaaactt aaatggtaaa aaaaacaaag atagtgcaac
   466441 agttactaaa attatcaatg caataaatga tcctaaaaaa tacaataatg accttaagaa
   466501 cagcatgata atttgcgaat gtaagcttta taatgtgata gatttataat tttaactgat
   466561 agagattacc atattgagta ttaacgctat ttattttgac ttaatggtat atttattgat
   466621 atagcattag atttaactta tgtgttaaat atgctacttc aatacagtgg tttaagtgaa
   466681 aaactttata aaaaatcaat cctttagttt tgttgcaaga tatattctta attaagttta
   466741 gttttaattg cgatgagttc tatcctaatt ttattgatat atacatataa aatgttgaat
   466801 acttataagg ataatattaa ttaattttat aaaatatttt cagatattga cacgcttatt
   466861 aaatttatta gaatcaaaga gatgttttgg agtagttact aataagcctg aaaatttaat
   466921 ttatttatta ttaagaaaac ttgatataaa ccataatgtg gtggtttttg gtgatacatt
   466981 agtatttaat aaaccacatc ttgctttgtt atgatatgct tgtgtacaat cagaaattag
   467041 tccaagtttt tatactatga ttatttgatt aatcaaaaag aaagatactg gtattaataa
   467101 tagtggagat atagagatta aggaattttt agataagatt gaaattatta ttaatgaata
   467161 agttaaagaa agagtaacta ttttgtatag aacacaaata agctataggt aaactatctg
   467221 acaacaaagg taatcttatt gctttttatg aaaaaataaa agaattaggt atttaaagta
   467281 aaaaggaatt aagccaatgg aaatttcaac taattattca atcaccaaag gtgaattaaa
   467341 agatagagtt attttagtta ctggtgcaaa tcgtggtttt ggtagggcaa taacacttga
   467401 ccttgctaaa gcaggtgcaa gtgttattat gttagggcgt gatttaagct ctctagaaaa
   467461 cacttacgac gaggtgataa attttggcta tcaaaaacct attctttatc cgcttgattt
   467521 agaaggtgca acacctaaac attatgagca gttacaaaaa gatatcttaa ataattttga
   467581 gcaacttgat ggacttattc ataatgctag tatcattgga acaatgatgc caattgaaca
   467641 atatgatatt aaactttggt attcaactat gcaaattaat attaacgcac cttttatgct
   467701 cacccaagta ttaattcctg tgcttaataa atcaagtgat gcccgtgtat tatttttttc
   467761 ttcatcagta gggcgtgtag caaaagcata ttggggtgca tatggtgtaa gtaaatttgc
   467821 tatcgaggga ataagtaaaa ccttatctga agaattagaa agaactaata ttaaggtaaa
   467881 ttcacttgat ccaggaagaa tgcgtactaa aatgcggcaa attgcttatc cagctgaaaa
   467941 tatatataat aatccactgc ctgagacaaa aagccctgta attgtgtatt taatgagtga
   468001 aaaagctaaa gagctaaatg gaaaacagat tactttattt agtatttgat aaaatttaaa
   468061 ataaatacta gtataataag ttgcttaatt ttaacgaaaa aatatctagt actataaaca
   468121 tattttttat tagagtctta ggtatctata tattgataat ttttaacgtt gtaatttaac
   468181 tgttagataa ggatggatgg tttttaagat tgctttaaaa acttggttat tgccagctac
   468241 tacattacct gtttttagat atttatctcg tcctgaaaag tcacctacaa aaccacctgc
   468301 ttctttaact aaaagcacac cagcagcaat gttccaaata ttaagttcaa tttcccaaaa
   468361 gccatctaac cgacctgcag ctaaatacgc tagattaagt gcagcagagc cagtatgacg
   468421 aataccagaa acctttagat aaatagcttt aaacatactt aaataagtat ctaaatgttt
   468481 tgattcttta aatgaaaagc ctgtaccaat taatgtattt tcaaaaccat tagtatgtgt
   468541 tatgcgaatt ctttgttcgt ttaagtaagc gccttctcct ttagaagtag taaataattc
   468601 ctccttaaaa ggatcgtata ctacagcatg ttttggctct ttattttcat acaaagcgat
   468661 cgagacagaa tattggggaa aaccatgtaa gtaattagta gtgccattta atggatcaat
   468721 aatccattga aaacgattat tgtctaaaat ttcactattt tcttcatata aaattgaatg
   468781 actagggaag gtatatttta actcgtttat aatggcatct ttagcagctt tatttacttc
   468841 agaaacaaag ttattagttg ttttattttt aatcgttaaa agattaattt gattatgata
   468901 tcttaaaatg atgttgccag cttttctagc gactttaacg gcaatattaa gcgtagggtg
   468961 ctgcataata aaaggaaaaa tgaaaaaagg aataaattat acctttgata aggtacgtgt
   469021 agttatggtt aatactaccg aacctggtaa tatcggtgcg gcagctcgtg caatgaagaa
   469081 tatgaattta tcaaaattgt atttggttaa tccaaagggt tatccatcag ctacggctac
   469141 ggctagagct agtggtgcag atgatgtact ttcagatgct atagtttgtg agtctttaga
   469201 agaagcttta aaaggtacgc atttagtgat tggtgctagt gcacgccagc gtaatattaa
   469261 atggagacaa atggatgttg ttggaacttg caataaaatt caaaaaacta ttacaattga
   469321 tagtcaagaa gttgctgtga tatttggtac tgaaaaatca ggtcttacta ataaagagtt
   469381 agatttatgt caaatactta tgactattcc tggtaatccc gattattttt ctttaaatgt
   469441 tgcatcagct attcaggtat ttgcttatca aaattatatt tataacaccc caactgaatt
   469501 taaagaaaac gttagtaaat tagctagttt tgatgaatta gaaagtttct acacacatct
   469561 tactcaagtg ttagagcata ttgaatattt taaagatcag cattctcaaa cattgttaat
   469621 gcgtcgatta cgttgttttt ttactaaagt agaacctaag atagaagaag tgtcaatttt
   469681 tagaggtatt cttaagaata tcaaaccttt taaaaggtta taaaatcccc attttctggt
   469741 ttttataacc ctttaaatga ttaattgatc agcttattta tacgttttac aaattcagcc
   469801 ggatctttaa gttgcccacc ttctgataaa acagcttgat caaatagaac cttgactaaa
   469861 tcctcatcaa ttttagtttt aagtttttta accaatgaat gagttggatt aatttcaaga
   469921 ataggtttag tatctggtat atcttgacct aaggatttca taattctttc catattacca
   469981 cccatttcat tttcatcagc taccaaacaa gaaggggatt cgctaagacg ggaagagatt
   470041 ttaatttctt taacctgaga gtcaagaatt ttttgcattt tttcaatgac tatttcaaag
   470101 tttttagcga cttcttcttt agcttttttt tcttccttag aatcaaaatc ttctaaattt
   470161 cctttagcaa ttgatttaag ttggataccg tcaaattctc taaaattact caccatccac
   470221 tcatcaacac gatcagataa tagcaggact tcaatatttt tttgattaaa attttctaaa
   470281 tgtggggagc ctttagcagt ttcataggtt tcagcagtta tgtaataaat ggctttctgg
   470341 tctttttgta tattttttat atagtgttca agcgttactg tttgtgtggc attcttgctt
   470401 ttattagtag taaatcgtaa gagttttgca attttatctt tattgatggt atcttcgact
   470461 acaccctctt tcataagcat gccgaattct tgccaaaatg ttgcataatc ttcaggttta
   470521 tttttagcca tcttttctag aactgataaa attcttttga cacttgcctt acggatagcc
   470581 ttaattactt tattatcttg taaaatttcg cgagaaaggt ttaatgataa atcagcagta
   470641 tcaatcacac ctttaacaaa gcgtaaatac agcggcatta gtgcctcatt atcttccatg
   470701 ataaatacac gtttagcgta aagtttaata cctcctttac gtttaggttc ccatatatcg
   470761 aaaggagact ttgaagggat aaatagtaat gaagtgtaat ctatattacc ttcaactcga
   470821 ttgtgtagct gtgttagtgg cgcttccaaa tcataagtaa gtgacttata gaattcatca
   470881 taatcttttt gcttaagatc ttgtttatct tgagcccaga aagcattagc tttattaatg
   470941 cgctcatatt caatatcttt attatcttca ctaactttaa ccatcataat tggcacagtg
   471001 atatgatctg agtattttga aataatattg cgtaaacgat aatcgtctaa aaattccttt
   471061 tcgtcttttt tgatgtgtaa tataactgag gtaccaaaat ctggacgatc aatactttct
   471121 attgaatatt tacctttacc agtagaagcc cattttgtac cttttttact tttgctacca
   471181 gcttttctgg taattatttc aaccttgtca gatacaataa agctagaata aaaccccaca
   471241 ccaaactggc caattaggtt agagtcttgt gcttgtgttt catttaaact ttttaaaaat
   471301 tttttagtac cagaattggc aatagtcccg atatttttat taacttctac ttcgctcata
   471361 ccaataccat tgtcagtaat agtaattgtg ttagcatctt tatttacatc aatgtgaatt
   471421 tgcaacgctt ctttcccttc aatcaaagta tcatctgaca gggatttgaa ttttaattta
   471481 tcaactgcat cagaagcatt agagattaat tcacgtaaaa atatttcttt atttgaatat
   471541 aaagagtgaa tcattaagtg taataattga gaaacttcgg tttggaagga atgtgtttgt
   471601 tttattgtca ttatattttt ctacctattt ttttttgcgt aaaatacgtt aatatggtcg
   471661 aaacataaaa aaacaagggt tatttttgta taaacaaatt actaatttta tttcagtatt
   471721 taaaagttaa gtgttattac tttattattc ataatcaaat ttatataaaa tatataatga
   471781 tttagtaatg tattcttgta gattttagaa tgtctaaatt ggtcgttatt aaatattaat
   471841 gatgtgaatt tacatcaaag gtttttacgt gtgctctgta tgattcctaa gattagagat
   471901 atgtcaggag gtaagtcagt taaacaaatt gttagttatt atttgtttaa tcatttaagt
   471961 tgtatgttat ttgtgaatga aaaacagcaa agaggtaaga ttaagaaacg tacagaatac
   472021 attatgccat gcagtagtga tctatctttt acaatataat cataatttat gttttactaa
   472081 agagttctta ggacttttta gtattaaatc taattaaagt ctatatttat cttaatttct
   472141 tttagagttg tcaaaaatat atgattagta ctatattaag agctaaaaag tcatgaattt
   472201 tcacacaaga tttgcagctt cttgcttaaa agtaggcggt gtaattagca atcctactga
   472261 tactattcaa gggttaactt gtttgccaaa atttgagtcc tctatgacta gaatactaca
   472321 atttaaacac cgatccagca ctaaaggttt gatattatta gctagtgatg tgtattattt
   472381 taaagactat gttaaagaca tctccttgtt gattaatgta actattaata ctcaaccaac
   472441 tacttattta ctcaaggcga acaggcgtac ttctcaatta ttaacaggtg actttgatac
   472501 aatcgcactt agattaacta ataatcaatt aattactaat ttatgtacag ccactcatag
   472561 tgctctagtt tcaagtagtg ctaatattac aagtaaatgt aatgcaagaa gtatgctaga
   472621 tttaaaatta ttttttagcg ataaattaga ttttattatt ccgccaaaaa cttacaacac
   472681 ccaagcgtca aaaattatta atctgcaaac tggagagaag attagatgat tgaaaaactt
   472741 caaaagtatt tactcatgct gcaatccgat atttgtgaac aatttgaaca gctagatggt
   472801 aaagtcaagt ttattaaaga cgcttggaaa aagccaaata atacaggcaa tggattgact
   472861 cgaatactag tcaatggtgc tgtgtttgaa caagcaggtg ttaatttttc aatcatacgt
   472921 agtaatgata tgccagcttc agctactgaa ttaagacctg agttagcagg acgtagcttt
   472981 actgctttag gggtatcatt agtgattcat ccacataatc cttatgtgcc aacatcacat
   473041 gccaatgttc gattttttat cgctaaaaaa aaggggaaaa ttcctatttg gtggtttggt
   473101 gggggttttg atttaactcc atattatggt tttgatgaag atgcaatttt ttggcatcaa
   473161 tcagctaaac aagcatgtga cctatttggt aaagacgtgt atttaaaata caaaaaatgg
   473221 tgtgatgatt atttttattt aaagcataga aatgaacaac gtggtattgg tggtttattc
   473281 tttgatgatt taaatgaagg tggttttgat aaatgctttg cttttatgag aagcgtgggt
   473341 gatggttata taaaggctta tcaacctatt gttgaacgga gaaaagatac atcttataca
   473401 gaccatgaaa ggcaattcca gctttatcgt cggggacgtt atgttgaatt taatttagtt
   473461 tatgatcgtg gtactttatt tggattgcaa acaggcggac gaacagaatc aattttaatg
   473521 tcaataccac cattggttcg ttggcaatac cagtatcaac cagaaccagg tagtcaagaa
   473581 gaaagactat atactcgttt tattcagcct caagattgga ttaatatctc ttttaaacag
   473641 aatgaaatat aatcttaacg ttaaacattt attttgtcct atgtcagtta tccgtttgag
   473701 tgagatgatt aaaaaaatta aaattaatga tacaattgaa atattaacta ccgatactgg
   473761 tgtgcttcat gacatatctg cttggtgtaa agttcatgga catcaagtaa ttttagttaa
   473821 tcaaaaaact aatgaaatta ttatttttgt agaaaaaaca gggtagaata aatctttatt
   473881 taaaaaaatt tattacacaa aataaataaa accatagaag aataatgctt gcaacggcgc
   473941 aggttatttt tgacaaagac tgtcagcaaa atatatatag tcaaaaaaag gagaaagtat
   474001 gtctgctaaa aatataatga agattattga agataataaa gttaaattca ttgattttcg
   474061 ttttaccgat accattggta aggaacaaca tgtgagtgtt ccagcacaca ccatgaatat
   474121 cgcaaaacta actgaaggac aaacatttga tggttcgtca attgctggtt ggaaatctat
   474181 tgataaatct gacatgatta tgatgccaga cacagcaaca gcggtaatgg atccatttac
   474241 cgaagaatct acacttaaca ttatttgtga tattattgaa tcaaataata tggctaacta
   474301 tgaaaaagac cctcgttcta ttgcaaaaag agctgaaatt tatttaaaca aaactggtat
   474361 tggtgatacc gcatattttg gcaatgagcc agaatttttt atctttgata gtgttaagtg
   474421 ggatacaggc tttggtttag gtaaagcttt ttatgaaatt aattccgaag aggcgtattg
   474481 ggagtctggt tctgattttg aaggcggtaa taaaggtcat cgtcctagaa ttaaaggggg
   474541 gtattttcca gttcctccgg tagattcatt acataattta cgtgcacaga tgtgcttagc
   474601 aattgaagaa atgggagtaa ctaccgagat tcatcatcat gaagttggta ctgctggaca
   474661 atgtgaaatt ggtgcattat ttaatacgtt agtgaaaaaa gctgatgaaa ctcaaatatt
   474721 aaaatattgt gttcataatg ttgcacattc ttatggtaaa acagcaactt ttatgcctaa
   474781 accaattgca gttgataatg gtaatggtat gcatgttcat caatcaatta ctaaaaatgg
   474841 taagaactta tttgatggta atgaatacgg taatttaagt gaaatggcgc ttcactatat
   474901 tgggggtatt attaagcacg ctcaagcact taatgctttt actaatgctt ctactaactc
   474961 gtacaagcgt ttagtgccag gttttgaagc accagaaatg ttggcgtatt cggctaaaaa
   475021 tcgttctgct gctattcgta ttccttttgt gtctcattct aaaggtcgtc gtattgaagt
   475081 acgttttcct gattcaacag ctaatccata tcttgcattt gcagcgatgt taatggcagg
   475141 tcttgatggt attaagaata agattcatcc tggaaaacca ggcgatgaag atttatatag
   475201 tttgacagaa aaagaaaaat tatcttttcc taaagtttgt agctcattag atcaagctct
   475261 tgaagcgcta gataaagatc gtgagttttt aaagaaaggt agtgtattta ctgataatat
   475321 tattgattca tttatcaatc ttaaaataaa agaagtaact gcacttcgtg cttctcctca
   475381 tccggtagaa tttgatatgt actacagtgt ataaaattta attttaaatg agataaaagc
   475441 cgtgtattta cacggctttt ttaaaatttg aattaagtta aaataactaa taaaatatca
   475501 aacaaaagat tatgacacaa caacgacaca attggacact aaaagaagtt gaagctttat
   475561 ttacattgcc ttttaatgat ttattatttc aagcacatag tattcatagg aagaattttg
   475621 atcctaatca ggttcaaatt agttcattgt taaatattaa aactggtgcc tgccctgaag
   475681 actgtttata ctgttcgcaa agttctaaat acgatacagg tcttgaacgc gaaaaattaa
   475741 tggaaattga tttggttctt aaacaagcta aacaggcaca agacaatggt gcaacacgat
   475801 tttgtatggg cgctgcatgg agaaatccta ctgataagag tataaacaag gttataccaa
   475861 tgattcaggg tgtaaaagat atgggtatgg aaacgtgtgt aaccttaggc atgttaaccc
   475921 agaaacaagc atttgtttta aaagaagtag gtctagatta ttataatcat aacattgaca
   475981 cttcaaaaga gaattattca aatattgtta ctacacgtaa ttttcaagac cgcttgaata
   476041 ctttagaatc agtacaaaat gctaatattc gtgtttgtag tggtggcatt ctagggttgg
   476101 gtgaagatca aactgatcgc gcctctatgc ttaggtcact gtctaattta gcaatacacc
   476161 cagacagtgt accgcttaat ttattagtgc caatcccagg tactccgttt gagaatattg
   476221 agccaccaac agaaagtgag tttatacgta ccattgcagt agcgcgtatt atgatgccaa
   476281 aatcagttgt acgcttatca gcaggccgca ctaagatggg agatactatg caagcacttt
   476341 gtttttttgc aggtgctaat tctatttttt atggtgaaca attactcact accgacaatc
   476401 caaatacgga cagtgaccaa gatttgtttg tgaggctagg gattaatcag aaacaagcaa
   476461 ataatctaca atctgtttaa ctgcattagg tttggcaatt tttaacgcat tgctagacat
   476521 ttgtttaatt tgatttttgt taatattaag taaaatcccc tctagtaatt caattgttaa
   476581 atctttttgc tcaattaata taccagcatt attatctgac aaaattttag cattatggaa
   476641 ttgatgatta tcaatggagt taggtagagg gattaagata ctggaggtgg ctgatagcat
   476701 taattctgat acagtcattg cacctgctct acaaagcaca atatctgccc aagcgtaagc
   476761 acttgccatc tctgtaataa atgcagttac ttttactgca ctattcttgt actgagattt
   476821 aactgtatca gcatgtaatt ttcctgtttg atgccaaata ttaatatcaa tattaagttg
   476881 cgtaactatc tcattaatcg gctttgagcc taaagaacca ccgataatta ataagtttaa
   476941 tttgttatta ttttgttttt caatagggtt gaatacaatt ggattaccag aagtagtagc
   477001 atttctaata aaagtatcgt caaatgcttg aaaagttttt gtggctattt tgttaagtat
   477061 tttattggtt gttcctggaa tagagttttg ttcatggatt actaacgtag ttttaaatac
   477121 ccaagccact aaaccgccaa tacctgaagt aaaaccaccc ataccaagta caacatcagg
   477181 tttaaatttt agaaaaattt ttatcacttg taacgtggca tagctcagta aaaatggtgc
   477241 ttttattagg ctaataacgt ttttacctcg taatccaaca ctactaactg tgtgtagttt
   477301 aatattatgt ttaggtataa tattgttttc cataccgagg tttgatccaa gccattgaat
   477361 attacttgaa tgctttttaa gctcgttagc aatggcaagt gctgggaaaa tatgcccacc
   477421 agttccacca gccataataa ggattttttt agctgtgtta aacacagtgt ttttgtttag
   477481 aatatttaca gcaattttct atatcaattc taagtaatat gagagaaact atcatatctg
   477541 atattcacct aactaataag tggtaaagta aaccctttgg gtagaatcaa gcctagacta
   477601 ataacaatat taacactaaa ttacataccc atacaaaata aataccaaag tcaaaataat
   477661 acttatattt acgattattt ttaagtgtat ttttagtaaa tttaaaactt ctaagtataa
   477721 tataagcgaa ggtaaacaat atatgttttt tcaaagatag tagaaataat attagtatgt
   477781 agttctgtca atttagtata ttgttaagtg tcattaccca aaactaattt aatcatttca
   477841 agaaactcaa gtttcaataa cataaattta atccaaacgc gtttaacctt tggcagtttt
   477901 tttcgataag ttatggaaaa aatactaatt agtaagcata tcaacgtaat gataaaaaat
   477961 aatttttatc aaaatataaa ggaactttta ttgtagtgta accaatactt aaacttaaaa
   478021 taataaaaat agtttgtttt ataagatagc cataactaaa agaatactcg tattgatgta
   478081 taagaacata gtacctaaat aaaaataaac aatgttaaaa caggaaaaag tagattttta
   478141 tctataattg aactattttt gtcaaagata agttcttaat aattaattaa ttttattaaa
   478201 ttatacttac caaggtaaga tttataattc tattagttgg gcttttttat tattattatg
   478261 ggataatatt ctcttttcgt ttgtaaaaat aaaaacaagt ttatgatttc tactgccaat
   478321 attactatgc aatttggtga aaaaccttta tttgaaaata tttctattaa atttcaggac
   478381 ggtaatcgtt atggtttaat tggtgcgaat ggctgcggta aatcaacttt tatgagaatc
   478441 ttaacaggtg aactcattcc tactaatggc acagttcata ttagtgatgg agagcgttta
   478501 ggaattcttc gccaagatca attttctttt gaaaatttta gtgtaattga taccgtgatt
   478561 atggggcatc atgagttatg gataatcaaa aaagaaagag atagaattta tgctttgcct
   478621 gaaatgagtg aagaagatgg tataaaggtt gcagagcttg aaatgaaatt tgcagaaatg
   478681 gatggttata tggctgaatc ttctgctagt gaattactgt taggattaga ctttccagaa
   478741 gagcaacatt atggttcaat gaataaaatt gcaccaggtt ggaaattgcg tattttacta
   478801 gctcaagcgt tattttcaga tccagatatt ttattacttg atgagcccac aaataattta
   478861 gatattaact caatccgttg gttagaggat gtgttaaggg aacgcaaggc gacaatgata
   478921 attatctctc atgatagaca ttttttaaat ggtgtgtgta cacatatgtc tgatttagac
   478981 tatggtgcgc ttaatacttt tcctggtaat tacgatcatt ttatgattgc gtcaactgcc
   479041 attcaagaaa aaatgcaagc tgacaatgct aaaaaagaag ttaaaattaa aactctaaag
   479101 cactttgtat ctcgtttttc agctaatgcc tctaaatcta aacaagctac ttcaaggtta
   479161 aaacaattag ataaaatcac attagatgat attaaaccat cttcaagagt aagcccatat
   479221 attatattta accaagaaaa aaagatacat agaaatatat tagaggttga agacctatct
   479281 aagagtttta atcccaaaga agatactgaa aaggatggta aatttgaagt tttaaaaagt
   479341 attaacttct tatttgaagc aggtgatcga atcgcggtta ttggccaaaa tggtattgga
   479401 aaaactacgt tattacgaac tttagttggt gaaataaagc ctgatagggg taagattaag
   479461 tggagtgaaa atattaatat tggttattat gcacaagacc atagtaaaga ttttgaaatt
   479521 gatatgagtg tacttgattg gatgtgtcaa tttaagagtg aaaaagacga tatacaagca
   479581 atgcgtgcag tgctaggaaa aatgttattt ggcaaagaaa atattggaaa aagtgttaca
   479641 tcactttctg gtggcgaaaa aggtaggatg ctttttggta aactcatgct gcaaaaaccc
   479701 aatatattgg taatggacga gcctaccaat caccttgata tagagtcaat tgaggcactt
   479761 aatttagcat tggataatta taaaggtagt ttaatattcg ttagtcacga cagggaattt
   479821 gtttcttcac tttctactaa ggtgttagaa cttaaagaag atggtatgca ttattattct
   479881 ggtaattatg aggattattt agttagtaaa aaataaaata aacccttaga gctctttaat
   479941 ttaattctag aaataagata aacgtgttat tttaatattg atttgattat ttattaatgt
   480001 tatttagtgt aagtaaaagt ttttatttta accaaaaaaa ataagtaaat gtttacaggt
   480061 attattcaag ccattggcaa gattaaaagt attgaactag gttcgttttg ctttcaagca
   480121 aagaaatcat tttttgatga agtaaaaatt ggtgatagca ttgctgtgaa tggcgtttgc
   480181 ttaactacta ttaaaataga tgataattat tttaaagtcg atatttcaaa agaaactctt
   480241 agatgcacaa tttttagcca tttaggtgtt gatagtttgg tcaatcttga aaaaacatta
   480301 agacttaatc aaggtatcga tggacattta gttagtgggc atgttgatgg tattgttaag
   480361 gttgttggac gatctattga aggtaaatcg atacgtttta agatgaaaac acctaagaat
   480421 ttgataaaat atatcactaa gaaaggttct atttgtatta acggagtgag tttaacagtt
   480481 aataatatta atgactgtgt gttggatatt aatattgttc catatacgct aaaaactaca
   480541 acattgggtg agttggaaat aaatagcaag gctaaccttg aggttgatat tatcgctaga
   480601 catattgagc gattattata ttttgaaaaa aatagttatg aaatctacca ttaaagaaat
   480661 tttaaaagac tacagccaag gaaaaatgat tatcctcatg gatgatgaag accgtgagaa
   480721 tgaaggtgat ttaatcatcc ctgctgaaac tgttactaaa gaagatatta atttcatggc
   480781 gactcatggt cgtggtttaa tttgtttaac attaacacag gaacgttgta agcaacttaa
   480841 tttaccactt atggttgcac aaaacaatga ttctaatggt actaatttta ctgtttcaat
   480901 cgaagcaata aaaggcgtaa ccacaggtat ctcagcagca gacagagcta agacaatatt
   480961 agatgctgtg gcaaaagatg ccaagcctga tgatattgta caaccaggac atattttccc
   481021 gcttatggca caaccaggtg gggttttaat tcgtgcagga catactgagg cagggtgcga
   481081 tttagctcgt cttgcagggt tcgaaccagc tagtgtgatt gttgaaattc taaataaaga
   481141 tggttcaatg gcacgacgtg atgatttaga aatatttgct aaaaaacacg atattaagtt
   481201 aggcacaatt gaaaacttaa tttcttatcg agttgaaaat gaaaaaacta tcgagcgtat
   481261 taacgaacgc gaatttaaaa ccgaatttgc tacttttaga ctaatttcat ttcttgatag
   481321 tattcacaat gaaactcatt tagctttggt taaaggtgaa attaatagta atgctgacac
   481381 gtacgtacgt gtgcacatgg aagatacttt taaggatgta ttaagagaaa aattaaatag
   481441 ttttagcgtt gacgctgtat taaagtgcat tgctaagtca gacagtggtg ttttattgtt
   481501 acttaggatg caaaccaacc aaagcatttt agaaaatatt gacaatgtga attgtgatat
   481561 tcatgatgat attaaaactt atggtgttgg tgctcagatt ttatctgacc ttggggttaa
   481621 aagaatgaaa atattaggca atcctagaaa actttatggc ttaaaaggct ttggtctaga
   481681 agtgactgaa tatgtagata ccaataagta aggaaataat aatggaattt aaatttaata
   481741 aagacggtag tagagatttt ctttcaaaga aaaaaattgc cattattgta ggttattttt
   481801 accaagatat ttgtgataat ctattattag catcacaaga aactttaact aaatatggta
   481861 ttaaggctaa taatatcaat gtattttatg ctcctggtgc atttgaaatt ccactattag
   481921 ctaaaaaatt agcaagccaa caaataaatg ggaaaaactt atacaatggt attgtggctt
   481981 taggtgctgt gattaacgga gaaactcctc attttaagtt tatttgtaac gaatgcgctc
   482041 gaggtgtatc aaatgtttct tatcagtatg aaatcccaac tacttttggc gttattacta
   482101 caaataatat ggagcaaact attgctagag ctgggggtta taagggaaac aaaggcgaag
   482161 aagcaactat ggcgatgatt ataatgcttt atttaatgca acaagcagat acccaatttt
   482221 tttaactatg tcctttaaaa ctccaaagca acgcacccgt gaacgtgtga tacaagcatt
   482281 gtatcaatat ctagtatcag gcggtgaagt atttcaaatt gaacaacaat ttttaaacca
   482341 aaaacaaggc aaaatttcaa aagttttctt ttcagattta tttatcaata tccttgaaaa
   482401 tagatttgta ttagatgagc taattacatc taccattagt cgggggactg aagagctagg
   482461 atctgttgaa cattctattt tatatctagg tacttttgaa cttaaattta actcagaagt
   482521 gccttataaa gtcgtaatta acgaatcact tgcattggca aaattatacg gggcagaagg
   482581 ttcatataaa cttattaacg tttcgttaga taaattagca cgaattctta gaaaaattga
   482641 attaattaac tagaaataca tctagatata aaatttatac atttttcggt gattttaaca
   482701 atgtctagaa tattgcgttt taacataggg ttgtttaagt ggttagaaac tttaaacagt
   482761 gaatgtttaa tattttttgt aagtattctt attctaaatt aggtgatagt aatttttctg
   482821 cttgttctaa cgaaatattt ttacgtttag cgtaattatt taattgtgat tgattgattt
   482881 ttgccacgcc aaaatatcta gcatcagggt tcgcaaaata ccaaccgctg acgctagcag
   482941 ttggtagcat ggcatacgag ctggttagta tcatgccagt gttattttta acgtcaagta
   483001 gtgtccatag tttttctttt tcgctgtgtt caggacaaga tggatagcca ggagcagggc
   483061 gaataccatc aaatttttct tggatgaatt gattgttgtc aaacctctca aaactataac
   483121 cccaaagctt ggtgcgtaat ttaaaatgca taagttcagt aaaaccctct actagacgat
   483181 cagctatggc tttaatcatg attgagttgt aatcgtcatg gtcagcttta aatgtagtaa
   483241 ttaataattc aatattaata ccggtagtca cagcgaaggc acccatataa tcattaatac
   483301 cgctgtcttt tgaagcaata aaatcactta aacaaaagtt tggggtgttg ccttttttgt
   483361 ctaattgttg acgtagatgg ttaagggtta ttataacttc gttattttca tcatacaact
   483421 caatgtcttc attgatacta ttagctggaa aaataccgat aacggcatta gctgtgagta
   483481 gtctttcatt aattactttt ttaaataaaa ccttagcatc attaaacagt atactagcag
   483541 attcacctac aatctcatcc gttaagatgt caggaaattt accggttaat tcccaagttt
   483601 gaaaaaatgg tacccagtca ataaattcga aaatttcagc tagattataa tttttaaaaa
   483661 catgaatacc taatttttta ggtttaacaa tagagttaaa agaaatatta ggtctattag
   483721 ctctggcttt ttctagagaa ataagtttac ttttaccttt attgatacga cgtttacgta
   483781 cattttcata gtcgatcttt gtgtcaatta aaagttgctg cttaagggtt tttgagagta
   483841 gggcagttgc tacgccaacg gatttagaag catcttttac ataaaaaact ccatggtcat
   483901 attctggctc aatttttacg gctgtatgtg ctttagaagt ggtagcacct ccaatcatta
   483961 aaggcaattt aagaccttga cgggtcatct ctttggcgac aaaaaccatt tcatctagtg
   484021 atggtgtgat taaccctgat aaaccgataa tatctacatt ctcttttcta gcagtttcaa
   484081 gtatggtttc ggtaggtacc attactccta gatcaataat tttataatta ttacaagaaa
   484141 gtaccacact aacaatattt ttaccaatat cgtgtacatc tcctttaacc gttgccatta
   484201 aaattttgcc ttgtgagctg gtaacacaat tttctttttc attttctaag aatggatcta
   484261 agtaagctac tgattttttc ataactcgag ctgatttcac cacttggggc aagaacattt
   484321 ttccagcact aaataaatca cctactacat tcatgccact cataagtggt ccttcaatga
   484381 ctagaatagg acgacctaat ttatcgaatg cttcttgagt gtctttatta atgtatgtag
   484441 taataccctt gactaaagca tgttctaaac gtctttctac tgcccatgtg cgccattcta
   484501 gattctgttt attatttttt tgctcgaatg tgttagaaaa ttttaaagct atatcaacca
   484561 aacgttcgcc tgcttgtttg ttgatgttta atacaacatc ttcaacagct tttttaagtt
   484621 ctgggtcaat atcattataa accattaatt gtcctgcatt aacgataccc atagtcatgc
   484681 ctgcttttac agtatgatat aaaaaaactg aatgaatcgc ttcgcgtacg gtattgttgc
   484741 ctctaaatga aaatgataca ttggatacgc caccagatat tttagcgtaa ggtagatttt
   484801 ttttaatggc gcgcgttgct tcaataaaat ctatcccgta attattgtgt tcttcaatac
   484861 ctgttgctat cgcaaaaata ttaggatcaa aaataatatc ttctggtgga aaattaacgt
   484921 tattaactaa aatataatag gcttttgtac agatttcaat ttttcgagct tgtgtgtctg
   484981 cctgaccaga ttcatcaaat gccataacga taattgctgc accatagcgt ttgcatagac
   485041 gggcatattg tataaattta gtcttacctt ctttaagtga aatagagttg acaataggtt
   485101 ttccttgtgt gcatttaagt ccagcttcga taatttccca tttagaagaa tccactatta
   485161 gtggcacttt agcaatatca ggttctgagg cgattagatt tataaagcgg atcatggcag
   485221 ttttgccatc aagcatacct tcatccatat taatatcaat catttgtgcg ccttcctcta
   485281 cttgtgtgcg gcaaatatcc aacgcctttt catattcctg gttaagaata aggcgtttaa
   485341 atttagctga acctgtgata ttagcgcgct caccaatatt tacaaaaagt gaatcgttac
   485401 caatattaaa agcttcaagc gctgataagc gacattctgg tttaatagta ggaatctttc
   485461 taggaggtat tctattaatt gagtcagcaa ttgctctaat atgatcaggt gttgatccgc
   485521 aacaaccacc tagtatattt actaaacctg atcttgccca ttcactaact tgttcactca
   485581 tggttagagc atttaaatca tattctccaa attcattggg tagtccagcg tttggatgag
   485641 ctgatacata ggtatcagct acgcgtgaca tttcagccac gtattggcgt aataaatcag
   485701 gtcctagtgc acaattaagc ccaatagaga ttggtttagc gtgacgcaat gagttataaa
   485761 aagcctcagt catttgtcca gatagggtac gaccagaagc atcagtaatg gtcccagaaa
   485821 tcataatagg taactcaata ccatcgtctt caaagacctg ttcaatcgca aagatagcag
   485881 ctttggcatt gagtgtatca aaaatggttt caatcaaaat aatatctacc ccgcctttaa
   485941 tcaagccacg agtggattct atataaacat caaccaactc atcaaaggta atatttctaa
   486001 acccaggatc atttacatct ggtgagagag aacaagtgcg tgaagttgga ccaataacac
   486061 cagcaacaaa tcttggtttt ttagtatttg aaaactcatc tgctgcttga cgtgcaattt
   486121 tagcactttt aaggttaatt tcataggcta atttttccat tttataatca gacatagaag
   486181 tgcgagtagc attaaaagta ttagtttcaa taatatcagc accgaccttc aaataatctt
   486241 tatgaatatt cttgataatc tgaggctggg taagtgagag taaatcatta ttaccttgaa
   486301 ctaagacatg ccaatcttta aaacgatcac cacgatactc ttgctcggtt aatttgtgtt
   486361 gttgaatcat ggttcccata gcaccatcaa gtactaaaat tcttttattt aaaagggatt
   486421 ttaatatttg ttttatattc ataattagca ttatacaagt atataacaag ttctaatttg
   486481 caataaatgg caagggccat agtgaaaaaa tattattatt tgaattgttg attgtaagtt
   486541 taaatataac tatattttta ggctttaata gccatgactt tgattacaag aataacgatt
   486601 agctagtttg gacaccgcat attaagcaat aaagtagttt ataattatat tggatcttta
   486661 ttcatgtaat taatattttt aagtattagt tttgtttagg tgttaatata ttattatgtt
   486721 ataatatact ttaatttgat taaatggaga tgtaacaatg aaaagttttt ttacaatagc
   486781 cttattaacg tttactataa gtgtgaatgc attttggggt ggtaataatt cccattggag
   486841 aaatggttac caagaagata acggtatatt tggttataat ccgtatgact tttgggatcc
   486901 tcgttggtat gcagaagaaa tgggtaatat gtttgatgaa tttgatgata atggctggaa
   486961 caacaactat aatggttatg ggcgtaatgg ttatgggcgt aatggttatg ggcgtaatgg
   487021 ttatgggcgt aatggttatg ggcgtaatgg ttatggtttt gctccaaatg gttatgtaaa
   487081 taccccatgg ggacctggta ttgcgcctaa agttactaaa ccagtagtac caacagttaa
   487141 gtaatattga attatgattc ataaaaaacc agcactagtg ctggtttttt attgcctatt
   487201 cccgtttcta aaagggaatg tcatcatcaa attcagaatt atcaataggt gtgataggtt
   487261 ctgatactga cggtactgtc ttttgttgtg atgtaaatgt agaagaagga ggtgatgatt
   487321 gttgaggttg gagtgtatta ttcatatcat catcattatc gcgacgatct aacatttgta
   487381 atgtgccatt taaaccagat acaactattt cagttgtata gcgatcagta ccagttttgt
   487441 cttgccattt tcgagttttt aatttacctt caatgtaaat tttagaacct ttgtgtagat
   487501 attgactagc aatatcagct aattttccaa ataaactaac tctgtgccac tcagttctat
   487561 caactttttg ccctgtattt ttatctatcc atctttcatt agttgcaaca gataaattag
   487621 ctactgatct accatcagag atgtatttta attctatatt ttgacctaca ttacctatta
   487681 aaattacttt gttgattcct aacatttttt ttgctccaat taattttttg ctgtttgttt
   487741 aatgggtgtt ttttgctttg ttataagtat gattatccac caaataattg caataaatgt
   487801 agtaaacaag aatacactat ttagattaaa tatgttgtaa atacgaccac cagaaattcc
   487861 tccaacaaac acacctaaaa attgtgatgt agaatacaaa cccatagcca gaccacgttt
   487921 atcagcactt gctcctgagg ctatgagtga aggtagaata gcttctaacg cattaaaagc
   487981 aataaaaaat aaagttagga ggatcaaaaa tgaagtgtat gtgagttctg tttgataaaa
   488041 cagaacttgg ctaataatca atagtgtgat agcacttaaa aacacaggct taattttttt
   488101 atgtttggaa gccaagatta ccattggtaa cataccaata aaagataaca tgataatagg
   488161 tagatatatt tgccaactat ctttaatgtc aataatattg ttttctttta aaacaattgg
   488221 catggcaata aaagcacaag ttaaaattaa atgtagtgca aaaatgctga aatctagtcg
   488281 tagtaaatca atattgagta cttttttaat gcttacaatt gacaaagcat attgttcttt
   488341 aggtttaatg tctggcatgg tagtaacaat aatcaaagca ataatagaaa gcaaagcaat
   488401 aacccaaaat aaaccagaga tacctaattt agcactaata atagggccta gtaataaggc
   488461 tagcataaag gctatgccta tttgtacacc cacaaaagca ttggctttag aacgttgatt
   488521 ttcgctaata aaatctgcta aaaatgccat cagtactgct gaaatagcac ctgaaccttg
   488581 taaggctcta ccaataacaa tacctatgat atctgttgaa ttagcaacca cgatactacc
   488641 aataaaaaag ataataagac caatagttaa catggatttt ctaccatact tgtctgataa
   488701 ataaccaaat gggatttgca ataatgcttg agttaaacca taaataccaa tagctaaacc
   488761 tattaagtaa ggtgtagtat tggtgtattt actagcatag actgaaaata taggaaaaat
   488821 cataaacaag cctaacatac gtgtggtcat gattaaagaa attttaaacg cgaaaactct
   488881 ttcttgttta ttcatctaaa taggttaaga accttagttc ttcaaagaat aatagggtgt
   488941 ataccaagga taattttttt ctagtactcg acgtgtatct tttgctagcg tacctgcgtt
   489001 aatagcatca taattggttg ccattaaatg tagtgctgca ggaactgagg gcgtattttg
   489061 atatttttca acgataaact tagtgcggtt aatagcagca atattagccc cttttttggt
   489121 gtagtaaata gctatgaaca actcatgtct tgataaaata tttctaagtg caactagacg
   489181 tgttatagtg tcttcagtat acttagtttt tgggaattta tcaatcaatg ctagatagta
   489241 gttaaaggcg ttacgtactg aattaacact acgttgggca ctatcagtaa agtagtcatc
   489301 taaaaatgaa cgggatttgt cttgtgaaat aacaccccgt aaataataag catatggagt
   489361 tgaaaaatgc tctggataaa atttaatata attatttaaa tgataaattg cttggtcata
   489421 gtctttgttt ttatacaatg cataggcaat ttctaactta gactgtagtg catattttga
   489481 gccaggataa gtagcttgta gttgttcaaa aagtttgata gctttatttg ttaatcctaa
   489541 tgattcttgt tctttagctt gagtaaagaa tgtctttggc gaccagcctt tagtaataga
   489601 ttctatttta atttcttttt gccaggagca gccattaagt aataatacta aaaagggtag
   489661 aatgatgaat aattttttca taattaaatg cattatttat tacagatatg tgaagaatta
   489721 tactggtgta gttgcattat aatagtaaat atttttactt caatttaact cttattgaat
   489781 gaaattacct gataaaagga tcctgataag cgagctatgt aatacactag aaaactatat
   489841 gtctaaaaaa caggttgaag gtgtttacca ggcttatatt gttgcggcga cagcacataa
   489901 tggtcaatac agacagtcag gtgaagctta tgtattccat cctatatcag ttgctatgat
   489961 tttagcagag ttaaagctgg actactgttg tattgttgcg gcaatattac atgattgtat
   490021 tgaggatact tcagttactt atgagcaaat taaacgtgat tttggtgatg aaattgcaca
   490081 tattgtggaa ggtctatcta agctaactgg gtttgaattt cattcaaata cagataagca
   490141 agcacaaaat tttagaaagt tactgttggc tatgagtggt gatatgcgag ttatagtaat
   490201 caaactagca gatcgtttac ataacatgca aacacttggt tctatgaaca gagacaaaca
   490261 acttagaatt gccaaagaaa cggtagaaat acatgcaccc attgcacgtc gtttagatct
   490321 taacagtatt agagttaagt tggataattt gtgctttgct attatttatc catttcgtaa
   490381 tagagttcta gtgagtcaaa ttaaaaaaca atgtggtaat cgcaagaaaa ttattaatca
   490441 tattgagaat gaaataaaga gccgattaaa tcaagaaggc ttgccaaacg ttgaaattaa
   490501 tggtcgtaga aaacaacctt gtagtattta tagaaaaatg aaaatcaaac atttgaagtt
   490561 ctctcaagta ttggatatgt atgcacttag ggttattgtc gctgatgttg cgcaatgtta
   490621 tcaatcctta ggtattattc ataatttgta caaaccatta ccaggtaagt ttaaagacta
   490681 catagcatta ccaaaatcaa acggttatca gtcgttacac acggtattat ttggttctaa
   490741 taaaattttt attgaagtgc aaattcgttc atctgatatg cattttattt cagaatatgg
   490801 cattgctgca cattggtatt ataaaagtgg ttctaaccat aaatcagcat tggctaataa
   490861 ctggttgggg tcactactag atattcaaca aaattcaggt acttctattg agtttttaga
   490921 agaaactaag gcagatttat ttccttctga ggtatttgtt tttactcctg aaggtgatat
   490981 tattcaatta ccttataaat cgactgtgct tgactttgcc tacatggtac atactagtat
   491041 cggtaatcat actcttagag ctaaaattga tcaagttgtt acacctattt ctactgaatt
   491101 aaaatcagga cagactattg aaattattac cgatgataaa gccactccta gatcttcttg
   491161 gttacaaatt gttgttacta taaaagctag atcttcaatt aaagcatatc ttaagaatga
   491221 gtcagcctct gaattaattc agttaggaga gtatttatta accaatgcac ttgattatca
   491281 aaatatagat acagataata ttgacgaggt tcaatggata aaatgtatta aagcgttaca
   491341 ttgtaattct aaagaagaca tgtacatgaa aattggactc tctgagattt tagtatcagt
   491401 tgcacttaac aagttgcaag gagataatat caagaataca attcaaaaga ttagtattta
   491461 taagactcaa ggaaaagcca ttagttttgc ttcttgttgt catcctattc ctggcgataa
   491521 agtagctggt gttttaacca cttctaaagg tatggtggta catagactga tttgtgctaa
   491581 tttagctcgt gctaaaagta aaaatgccca atggcttaac attgattggc aggctaatga
   491641 ggatgaggaa tttaaagcaa tgattgacgt ggatgttgct aatcaaagag gtacactcgc
   491701 ttctattacc agtgttattt caaagatgaa aattaatatt gagtttttag agattcaaga
   491761 aaaaaacaat actatcaaat cacttaatat agtgattagt gttgcaaatt ttagtcaatt
   491821 aaatcaagta ttcgtacaac taaagacgtt aaaatttgtt agagaagtta gcaggatgtg
   491881 attagaaaaa ctactaaatt tatacatagt aaaccttagt ttggttaaaa ttcaatttta
   491941 actcaaggga tttttatgaa ctggacagat tctttagata ttgcaatagc cttgaatgat
   492001 gcctatccaa aaattaatcc ttgtattgtt aactttgttg atcttagaca aatggtgatt
   492061 gcactaaatg aattcgatga tgatgtaaat aaatcaggtg aaaaaattct tgaggttatt
   492121 caaatgaact ggatagaaga aagggaatga aacaatttat tgtttttatt ttatcacttt
   492181 atacaaccct ttcttgggca gtattagaag tcactatttt caaacaggag gaaaatactt
   492241 ttcctattgt tatttctgat ttttttgttg tgggtgatgc aagccaaggc aaagttattg
   492301 cagatattat gcgtaataat tttaatcgtt caggcgaatt tagtgttgtt aatgcaaatt
   492361 atatcattag aagtaaacct agttttgata aatggaaggc aaaaaaaatt gaagctattg
   492421 tactgggtaa gttagaaaag attagtaaaa aaatctttaa tgttgagatt gaattactgg
   492481 atgtttattc taagaaaaca ctctataaag atatatttac cgtacataat agtggtatca
   492541 gaagaattgc ccattattta tctgatcaaa tttatcatgc tttactaggt aaaagaggat
   492601 tttttaatac acgtctagcc tatattactg ttattaataa agacaaaggt gaacgtgaat
   492661 atcgcttaga gatatcagat tctgatgctc aaaatccaca aactatctta aaatctagag
   492721 aacccctttt gtctcctgtt tggtctccta aacaggataa gattgcttat gtatctttta
   492781 aaaactctcg ttcagaggta ttcattcaat acccatttat acgtaggaaa atacaaaaac
   492841 tgccttattt tgatggcatt gcttcatcac cttcttggca tccgaatggt gaaatcctct
   492901 tacttacatt atctaaaaat ggtaacaaag atatttactc ctatcagtta tcctccaaaa
   492961 aactaacacg actaactata gatatgggaa ttgatactga agcaagctat tcaccagatg
   493021 gtaataaaat tatatttacc tctaaccgtt ctggacaagt acaagtttat attaaagatt
   493081 taaaaactaa taaaattaat agagcaactt ttaaaggcag atataatgcc caagccgttt
   493141 tttcacctga tggtaaaagc ttgattatgg tacataagat agatcaagat tatcgtatcg
   493201 ctttactaga tattgctact aaagacttga aagtcatgac taataatcaa cttgatgagt
   493261 ctccattctt ttcgccaaat ggagatatga ttatctttgc tactaaccaa ggtggttttg
   493321 gagtactttc tgtggtttca atatgggggc gtcaaatttt cgagttaact agtaaagtgg
   493381 gagaagttag agaaccaaat tggtcacatt atttaaaata ggagccgtta aaatgttaaa
   493441 attaatatct ttattaatag tagtactgtt gtcgtcatgt ttatctgggg acgatttgta
   493501 tagaaaagta ttacctaagt caagcgtagt taccattgaa gatagaatga aaaacgtgca
   493561 agaaaatgtt tttgagactg ataaatctaa ctttacatct ctcagggttg atgacagaat
   493621 taaaagtata ccaagtatta ctgaatcatt tattgtaaca agttttagag aaactgatgt
   493681 taactttatt ttgtattttt ctgacgatgg cactgagatt aataagacct caattaaaca
   493741 aattatcaaa catgccaact ttatgcgtaa caatccaaca ctaaagttac gtctagaagg
   493801 tcatacagat gaacgaggta cacgtgaata taacttagca ttaggtgaaa atcgtgcttt
   493861 aaatgttaaa gaaatattag gcttgtatga tctttcttcc agaattgaag ttattagttt
   493921 tggtgaagaa aagcccatga cgcagcaaca cgatgaagat gcatggcaga aaaataggcg
   493981 tgttgagttt gtttatcaat aaagtttcat gtattatctt ggtttattca tttttttaag
   494041 tatttttatc ttacagtctg cttattcagg tattaataca gaaaaagtag taatagatca
   494101 taatcaaaaa attaagcgat tgttgcttaa aaataaaatt ttaataggta aatttgagtt
   494161 gttagaacag caacaagaaa taagtactgg aaaaattaaa gagttgttta acttaattac
   494221 ttatcaaaaa tccagtggta taattaaaga aacttcattt aaaacgagag agtatgataa
   494281 aaaagctaaa cgtgtttata cgcaggctcg tagtttatta ataatagagc aatatgacca
   494341 agctattaag ttatttaagc aatatttagt agattattcc aatagtagtt acacttcaga
   494401 tgtatactat tggttagcta aatcttattt ggctaaagaa gattttcata atgctaaaaa
   494461 tacttttgtt gtatttcaac aacaaaaccc attgcattat aaattttcaa actctttatt
   494521 tgatttggct aaagtatata tagaacttaa taaacaagat aaagcacagg gtttattgag
   494581 tacaatgctg gtgaaatttc cttcacataa agcgattaat agagccaagc aactacttag
   494641 taaaatcatt attaaatcaa aggttaataa ttaactttaa attaaagtga aggttatatc
   494701 tattcctgat attgatttag atacgttatc ttacgctaat cctacacgtt atccattttt
   494761 attagaaagt gttaatcata attctaataa tcgtttttcg atattgtttg cacatcctgg
   494821 taaaaaaatt gtgttgaatg acttggaaga atttgatttt ttagataaac tcactactag
   494881 tatagataca ctgcttattt acagtgattt gccttttact ggcgggtggt ttgtatatct
   494941 ctcttatgaa ttaattgggc aaatagaacc tactttaaaa caaataatgc atacaagcga
   495001 tcaacctatt gctatggctg tgcaaattcc aacagctatt attattgatc atacgaacca
   495061 tcagacctat ttattagacc aatttggtag taaatataga atagatcaag tattagcaga
   495121 tatcaaacaa ttaaagttaa tacctgattg taaattaaca ggtactttat atactgaaga
   495181 agaagctaag tttttattag gtgtggcaaa aaatcgtgaa tacattaaag caggggatgt
   495241 ttttcaagta aacctttcaa gacaatggca ataccattta actaatgata ttactccaac
   495301 tcaaatttac caagcactaa aaaaaaccaa tccagcccca ttttctgcac tggtacaatt
   495361 acaaacgttt agtattatct cttcttcccc cgagcgtcta tttagcgtgg atggaaatgt
   495421 catacaaagc agacctattg caggtaccta cccacgtggt ataggtagtg aagataaacg
   495481 tctaaaacaa caactcatta accaccctaa agaacgagca gagcatatta tgctacttga
   495541 tttagagcgt aatgatttgg gcaaggtgtg tgaatatgga agtattaaaa ttgatgaaat
   495601 tatgggttta gaaagctatc catttgtaca tcatatcgtt tcaaatatca aaggaaaaat
   495661 taaactaaac actactatta aacacctaat tagtgcatta ttcccaggtg ggactattac
   495721 tggttgccct aagattcgct gtatgcaaat tattcaagaa cttgaacaaa ctccacgtca
   495781 atcctataca ggatcgttag gttatgtcag tagtaatgga aaaatggatt ttaacattct
   495841 tattcgcact attagcaaac aaaacaatct gctaacttta aggacagggg ctggcattgt
   495901 gttcgactct attgctaaac aagagttaca ggaaaccaaa cataaagcca agggtatgct
   495961 taaaattttt gcataatata acagaatgtt gattaatata taattttaat gcaaaatata
   496021 ctatgtctat tcaaatatat ttataatcat ttgtactatt attttaatgg tgttatttct
   496081 ttaaatggct attaaggctg aaatttagaa gtcatagggt agcgacgttc tttaccaaag
   496141 gcatttggac tgattttagg tcctggtgca ctttgtcttc gtttgtattc attgttaagt
   496201 accatttgtg taatatattt aacggtttgt tcgttaaatc cttgtttaat gatatgttta
   496261 actgaatatt tttgttctat aaatagtgtt aatattgcat ccaattcatt ataagagggt
   496321 aaggaatctt gatcagcttg attaggtgcg agttcagcag atggttttct atcgataacg
   496381 cgttccggaa tgatggttga tatggtgttt ctatatttag ctaattggta aactaaagtc
   496441 ttgttaacat ccttaagagg agcgaaacca cctgacatat caccatatag agtggtgtag
   496501 ccaactgcta tttcagattt attacttgtg gtaagtacga tttttcctaa tttattagag
   496561 attgccatga gcagtgtacc ccgtatacgt gcttgtatat tttcttcagt agtatcagtt
   496621 tccataccga taaatagagt attgagttgt gtgttaaaac tgtctactat gatatgaatg
   496681 ttgatttcat gatagtcaac attcattgtt gtagcctgaa ttttagcatc ttcaagactt
   496741 atgtttgaag tatacttata aggcatcata atggctttaa tgtgctcagt gcctatagca
   496801 tcagcagcaa tagcaagggt aagtgcagaa tcaataccac cagataagcc aattactacg
   496861 ccattaaaaa catcattttt ttcaatgtaa tctttggtag caagtaccaa ggcatcataa
   496921 atagttttct caataggatc agtgtcaaat aatgtaatag gggaggtaaa actaacgctt
   496981 tgaactgctt ctttaaataa gggtaattgc aaagtgatat tggcatttga attcattgca
   497041 aaagatgcgc catcaaatac taattcatct tgtgcaccaa ccatattaac gtaaataaaa
   497101 ttagttttag tttctaagac acgttgttta atttgttcaa tgcgttgtga gtgtttgcca
   497161 atctggaatg gagaagcatt aatgctaatt atgatttgca cacctttatt agctgagata
   497221 gaaatgatat ctgatgtcca agcatcttca catataacta ggctaatttt ttttccttga
   497281 cattcaaaaa taaaaggctc attacctgat tcaaaataac gtttttcatc aaatacacca
   497341 taatttggta gattctgttt atgataaaaa tacacttgcg aattttgaat aagataggca
   497401 ctgttgtata aaatatcgtc ttttttgtat ggcgctccaa atataataga aatattatta
   497461 gagatggttt gattaattaa agttacttta tcttggactt gttgaacaaa cccttcatgt
   497521 agcagtaaat cttcaggagg gtagccaatc agcgataatt ctggaaaaac taataaatca
   497581 caacctcgaa tatatgcttc ttgggttaat ttaataattt tttgagtgtt tccatttaaa
   497641 tcaccaacaa taggattaat ttgcgcaatg tcaattttga tagattttga gttatttgca
   497701 agtttttcta gttgattttg caaaaatatg gactttggtt tactatcagt aaattttgca
   497761 tgttcaagtt tagtatgggt gacgactttt gcagggttaa tgtttaaaat attagcaaat
   497821 aactgatcgt tggtttcaga aagggtagct tttcctgatt tatatttact taaattagat
   497881 tgattaattg aatatttttg tgagatgtta tagtctgaaa gaccagtttt tttgagtact
   497941 ttattcaagt aatatttagc cctatttgtc attatttatg tcttaatttt aaatataatt
   498001 taacacctat tatagttaat ttttaccatc cttatttggc aattaaatta gttaaaatat
   498061 actaaatata ttatataaat tattgattta taattatttt ttaaatttta aaaagcaaag
   498121 aacaattaat agtattatgc tataatttta attttatgca ataagcatta atcaattcta
   498181 gtaataaaaa atatacaaaa atttgataaa aattaagacg caatagtatg ttaaaaaatt
   498241 ttgctaaata gcaagaagtt ttattttaag aaaaacctta acataataat aatttagaca
   498301 tgtttaatcc taaaaaaggg ctaagtttaa accaaagtca gaatcttgaa acaaatataa
   498361 agataaaagt acctctgatg aaaattttaa atagaataca aaaaagtaga tttaaaatat
   498421 catttttaaa tgtatataaa tttgtttcaa aatgaaaata ggtattttac taaccaatat
   498481 tggtacacct gatgccccta caaaagcatc tttaaagcga tatttatctg aattcttatc
   498541 agattctaga gtggttagct ttcctattaa atttaaattc atatggtggc tggtgttaaa
   498601 tgttgttatt cttaatacaa gacctaaaaa atcagcaaaa aattatgcca aaatttggga
   498661 taggattggt attggttctc cattattaag cattactaag ttacaattac aaggcgttaa
   498721 aaaaactttg cttgagcgac atgaaaattt agtatttgaa atgggtatgc gttatggaaa
   498781 tccttctatt tcatcagtgt tgaataagtt acttaatcaa gattgtgaaa aaattattgt
   498841 tttaccgctt tatcctcagt actcgaacac aacaacactc tcaacattag atgttattaa
   498901 tcaagtacta aatgactctt ggactaaaaa accagaaata atctttattg agtattattg
   498961 ttacaatgat gattatattc aatcccttgc taatacggta ttagaacatc aaattaaaca
   499021 tggaaagccg aataaattga taatttcatt tcacgggatc cctcaacgat atattgatag
   499081 tggtgatata tattacgacc attgtgttga tacagctaaa ttacttgcta aaaagctaga
   499141 tttgaataag agcgattatt tgtttagctt tcagtctatt tttggtcgag aaccttggac
   499201 taagccacaa accaaagaaa gattagaaac attagcttgt gatggcgttg agcatattca
   499261 aataatttgt ccaggatttt catctgattg cttagagact ttagaagaaa ttgagtgtga
   499321 aaatagaaat tattttattc aatctggtgg tctcaaattt agttacattc ctgcattaaa
   499381 ctatagggat gatcatatta agatgctttc taatttgatt tctaattatt tatagtatgt
   499441 taaattattt ttatctataa ataaattgta aaatacgcta tttttatcta taaatatatc
   499501 gtattttacg agcattatta tgtagtccta ctaggagtat caatgaatca agatattaaa
   499561 gtcactaagc gtaatggaca acaagagtct attgatatgg aaaaaattca tcgcgttgta
   499621 cattgggctt cacaagactt aaaaagtgtt agtgttagcc aagttgaaat caatgcacag
   499681 ttagcatttt ttgatggtat taagacggaa gatattcatg aaacaattat taaatcagca
   499741 gcagatttaa tttcaacaga cataccagat tatcaatatt tagcggcacg tttatccatt
   499801 tttcatttac gtaaaaaagc gtttaaatcc tttaccccgc caccattttt tgagcacatt
   499861 aaaaaaatca cagatttagg tatttatgac aaagatattc ttaataaata tctcaaagag
   499921 gaaattgaaa tattaggttc ttatattgat cattggcgtg atatgaattt ttcctatgta
   499981 gctgttaaac aactggaagg caaatactta gttcaaaatc gtgttactgg cgaaatttat
   500041 gaatctccac aatttcttta tatgttagtg ggtatgtgct tatttcaaga atatgaagtg
   500101 agtaaacgca tgaatactgt gaagcgcttc tatgatgcag taagtttgtt taaaatctcc
   500161 cttcctacac ctattatggc tggggttaga acacctacac gccaattttc gtcttgtgta
   500221 ttaattgaaa cagatgatga tttagattct attagtgcca ctgctggggt tattgttaaa
   500281 tatatatctc agcgtgctgg gatcggcatt aatggtggta aaattcgtgc aattggtagc
   500341 cctattcgcg ggggtgaggc aacacataca ggttgtattc ctttttataa acatttccat
   500401 accgctgtta aatcttgctc acagggtggc gtgcgggggg gtgcagctac tttattttac
   500461 cctttgtggc atttagaagt tgaaaattta ttagttctta aaaacaacac aggaacggac
   500521 gaaaatcgta ttcgtcattt ggactatgga gtgcagttta acggcttaat gtatcaacgt
   500581 tttttaaaag atggcgatat tactttattt tcaccacatg atacccctga tttgtacaat
   500641 gctttttttg ctgatcaaga agaatttaaa cgtttgtatc ataaatatga acaaaatact
   500701 ttaattagaa aacacactat taaagccaga gaattatttt ctaagtttat acaagaacgt
   500761 gctaatacag gccgtattta tttacaaaat gttgatcact gcaataccca tagtgcattt
   500821 aatgccaaac aagcacctat taaacaatcc aacctttgta tggaaattac tctaccaact
   500881 aaacccttat attcaattca agatgaacaa ggcgagatag cgctttgtac attatcagca
   500941 gttaaccttg gtgcattaga ttctttaaat gagttagaaa cgttaactga tatcattgta
   501001 cgctcattgg attgtttact tgattatcaa gattacccaa ttaaagcagc tgaacttgct
   501061 agtaaaaatc gtcgaacact cggtattggc gtaactaatc ttgcttatta tttagccaaa
   501121 aatggtgcaa aatattctga tggatcaggt aatcaactca ttcatacaac ctttgaggca
   501181 ttacagtatt attcattaaa ggcttcaaat acgttagcaa aagaattagg tgcttgtcca
   501241 ttattttttc aaacccaata ttcacaaggt attatgccta ttgattctta taaaaaagat
   501301 attgatgcgt tttgtgattt caaattaaaa tttgattggg atacactacg tcaggatatt
   501361 acatctaaag gtcttagaaa ctcaacctta acagcactta tgccatgtga aagctcgtca
   501421 caaatctcta attcaactaa tgggattgaa ccacctagag ggtttgtatc tattaaacag
   501481 tctaaagatg gtatcttaaa gcaaatagta cctgattatg aattattaaa aaaccagtat
   501541 gagctactct gggatattaa agataatgaa ggttatctac aactttgtgg gattatgcaa
   501601 aaatttgtag atcagtctat ttctactaac acacattacg acccttcaca gtttgagggt
   501661 aataaagtgc caattaaatt gtttttaatg gatttgttga aagcatataa atatggcatt
   501721 aaaacgcttt attatcatac aactcgtgat ggtggcagca atgatatgtc agaaaaagaa
   501781 gatgataaca actgtacaaa cggtatttgt aaactataaa aggagctttt tagtatgtca
   501841 tatagtattt ttaccaaaac aataagcaat atactaattg aaccaatgtt ttttggcaat
   501901 acagttaatg tagcacgttt tgataagcaa aaatttgaaa tatttgaaaa gctcactgaa
   501961 aaacagcttt cttttttttg gcgtccagaa gagattgatg tttctaaaga taagatagat
   502021 tttgctaaat tactacccaa tgaaaaacat atttttattt ctaatcttca ataccaaatc
   502081 ttgctagatt cagtacaaag tcgctctcct aatattgctt ttttgccgat tgtatcattg
   502141 ccagagttag aaaattggat tgaaacttgg tcattttctg aaactattca ttcacgctct
   502201 tatacacata ttattcgtgc tattgttaat gaaccaggca tagtattcga tgatattatg
   502261 aaaatagatg aaattattca gcgcgctgaa agtgtgtcta aacactataa tgagttaatt
   502321 aaatgtactc aggcttattt attacacggt ataggtaagt ttaaagttca agataaagag
   502381 atattaattg acttgtattg tttaaaaaaa caactttatc ttactattat gtcagttaat
   502441 attcttgagg cggtgcaatt ttatgttagt tttgcttgct cttttgcctt cgccgaaaga
   502501 aaggttatgg agggtaatgc taaaattatt agaatgattg ctcgtgatga ggctctccat
   502561 ttaacaggta ctcaacatat actgaatttg atgagtgacg gcaaggatga tcctgatatg
   502621 aaaaaaatag caaaagagtg tgaaaaagaa gtaattacca tgttcaaaga agcttgtgaa
   502681 caagaaaaag attgggcaga atacttattc cgtgatggtt ctatgatcgg tttaaatgca
   502741 aagatgctaa aacaatattt agaatatatt accaacgtac gtatgaaggc tctaaattta
   502801 agtcctgtat ttgatgaatg tattaatcct ttaccttgga ttaaccattg gttagattct
   502861 gataacgttc aagttgcacc ccaagaaact gaaattacat cttatttagt cagcgctatt
   502921 gataatactt tagataaaca agactttgat tttaatagct ttaaattata gctgattaaa
   502981 tgtttaggat agaaattgat aacatcaatg gtaaaaccaa atcattatat gcttatggag
   503041 atcactccat tcttattgaa cttgaacagc agaatatact cattaatcat tcttgtcgtc
   503101 aaggacattg tggtagctgt atattgcaac tattatctgg tgacgtcatc catcaggatt
   503161 ctataataca cttatcacaa ggggaaattt tagcttgtag agcaacacct gttacggata
   503221 tcaaaattgc ttcaagaaat tgaataaata ttattaatgt tgtagtatat tcatcaatta
   503281 aaaaccaaaa tagagattct ataaatctat ttttattgtt cctgtgtaca catacttata
   503341 atactactat caaatagctt acgtcctgct tctattatat aaataataag tatgatatac
   503401 ttactttgat tctaataagt tttattgatt atttattaag taaaaaatta tgaagggtgt
   503461 attctttctc taattcttta tacaattgtt ctggcattaa atcggaatgt ttttccatta
   503521 tacgaaaggc aacaacgttg tcttcctcta cgccccaaag tttaatataa gtgcctttct
   503581 tataaccatg tttctgtcta aagatattaa gttgattttt aacaagatag cgtttataga
   503641 gttctgatac atccatactc attgtagtta gcgctttaaa aaaaagccct gttatttcat
   503701 ataaagcatt ttgtgattta ttcacattag cactacttgc tatggctact agtttttcta
   503761 aaatttctat tacaagttct ggatttactt ccctttctgg ctttatattt tcataattat
   503821 gagcaaattg agtatcacca agatgaatag cttcagacat aataaaatgc caaatatcca
   503881 ctaactcaac tttaaaatta tctaaatcat gctccttttt aatatctttc cagtgtttcc
   503941 aattaaacga atcaattgcc tcagtagctt ccatataaat acaacgtaac caagaaatat
   504001 aacgtccgtc ttttgttata ccatcagtcc actgtacacc attagtgttg ttatttaact
   504061 gcttttgtaa ttcaaacatt tgcttaattt tgctcattga taaatccttg taataatatt
   504121 aaaaattatt gatgattata atgaaaacat ttggtaagtt aaaaattaat taattgtgac
   504181 ttaggagagt ttttaacttc taactctgat cttgacttgt gtaatgaata atatttatta
   504241 cgatagggtt gtgtgatgat acaagcgcaa gcatttaagc tttatcaata gagtgcattt
   504301 aatagtatat tgaaataaat acaaaagttc aataacgtgt aattgttatt caaggtactt
   504361 ggtttaactt tattgtgtat taaaaacttt acaaaatagt tcagctgttt tttgtgtatc
   504421 gtatagtgca gaatgtgcac aagtatcatc ccactcaata tcagccttac gtatggcttt
   504481 agctaataca gtttcaccat agcataaggc tgataaacta accgtatcta gggttgagaa
   504541 ttgatgaaaa gggcttttaa gtttacatct gttagttgca gcacgtaaaa agcctaaatc
   504601 aaaaaaagca ttatgtccca ctaaaatagc acgagtgcag tccttttgtt tgagttctgt
   504661 atatacctta gtataaattt gcttaatggc atcaacctct ttaactgcca ttctaaatgg
   504721 attatcaaca tcaatactat taaactttat cgcactaggc tctaatatac ttcctttaaa
   504781 tggttcaatg tgaaaatgtt gtggtttttt tgggtataaa ttattcattt tatcaatgcc
   504841 aattataatg gtgcaaattt ctaacatagc atcagttttc tcgttaaaac cacctgtttc
   504901 gatgtcaata actaccggta aataaccacg aattctatct ttaattaaca tttttaaaaa
   504961 aaattgatga attacgttct tgattaaata aagcttgatg tttttggggt aaatcaataa
   505021 tattcatttg gataaagcca tgtttaataa accaatctgt gctatgttta gttaatgcga
   505081 aaaccttgga aaatttttta gcttttgctt taaacataat tttttcaagt aactttaaag
   505141 atagccctgt tttttgtgct tttttagata ctgctaatga gtaaatttct cccatattat
   505201 cctctttaca atctttaagt cctgcacaag caatcaattg attgttgttt gtcaaataaa
   505261 caaaatctcc aatattttca ttaatttgtg cctcagttct aatcaatatt ttaccctcct
   505321 cagaaaaagg tttaactaga gttagaatct gttcggcttt aatcaaacta aatggttaaa
   505381 atattaacta aaaatgtcaa ttttagtcta aaatttaatc tttatttttg gataaaaaaa
   505441 ttatgtgcat cccaagaaaa tattcctcac aagttgttga tggatttgaa cgcgcaccaa
   505501 gtcgtgctat gctttacccc attggtttta aaaaagatga ttttagcaaa ccccaggttg
   505561 gtatagcaag cacttggtca atggtaacac catgtaatat gcatattaat aaattagctg
   505621 ataaagccga aaaagggata aataacgcag gtggtaaagg tgttatcttt aacaccatta
   505681 ccatatcaga tggtatttct atgggctctg aaggtatgaa atattcctta gtatcacgcg
   505741 aagtcattgc cgattcaatt gaaacagttg ttggttgtca agggtttgat ggtgtggttg
   505801 ctattggtgg gtgtgataaa aatatgcctg gttgtattat tggcttagca cgtcttaatc
   505861 gccctagtat ttttgtttat ggcggtacta ttcaaccggg taaaaatcgt acagatgtgg
   505921 taagtgtttt cgaagcagtt ggccgatttt ctaaccatga aattgatgaa atagaactag
   505981 aaaatattga aaaaacagcc gttactggag caggttcttg tggtggtatg tacactgcta
   506041 atactatggc atcagcaatt gaagcattag gtatgagttt acccaactcc agcgcacaaa
   506101 atgctatatc agatgataaa aataatgatt gtatccaagc tggagaagct attcttactt
   506161 tattaaataa agacattaaa ccccgtgata taatgactat gaaagcattc gaaaatgcca
   506221 tcactgtaat tattgcattg ggtggctcaa ccaatgctgt attgcattta attgccatgg
   506281 caaatgccgc tgaggttaat ctcaaaattg atgattttac tcgcattggt aaaaaagtac
   506341 ctgttattgc tgaccttaaa ccatcaggta aatatatgat gagtgaattg gttgaaattg
   506401 ggggtacatt accactaatg aaaatgctac ttgatgcagg actattacat ggggattgca
   506461 tgacagtaac aggaaaaact ttagctaaaa atttaaaaaa tgttcaatca tatgctgatt
   506521 cccaagaaat tattagagca ttagataacc caataaagaa agattcacac cttagaattt
   506581 tgcgtggtaa ccttgcaatt aatggtgctg tggcaaagat tactggtaaa gaaggttcaa
   506641 gtttcaaagg tacagctaaa tgtttttctc atgaagaagg agcgcttaag gctattttaa
   506701 atgaccaaat aaaagcaggt aatgttatcg ttattcgtta cgaggggcct gttggtggtc
   506761 ctggtatgcg tgaaatgctt gctcctactt ctgcagttat ggggaaagga ttgggtggta
   506821 aaattgcact tattactgat gggcgcttct ctggtggtac acatggtttt gtagtcgggc
   506881 atatcactcc tgaagccttt aaaggtggag tgctagcagt ggttgaagat ggtgatgaaa
   506941 ttataattga tgcacaaaat aacgttttag aactattagt tgatcaagct attattgata
   507001 aacgcttatc taaatggacg caacctaaac caaactacac taaaggtgta ttagcaaaat
   507061 ttgcaaaact agctaaatct gcttctgaag gtgcagttac tgattaacta atacttatct
   507121 tttgtttttt atgaataaaa gaaggtttta tagaaatttt agtattattc tcttattcta
   507181 taggagaaaa tattatttgt ctattgtcaa gattaacaga ggtaacttgg attttaatag
   507241 tatttcctaa ttgataaact ttaccagtag gttctccttt gagctgatga ttaatgttgt
   507301 caaaaatata ataatcatct ttcatatcac acaaggcaat cataccttcg acaaatatat
   507361 cagtaagttc aatgaagatg ccaaaactag caataccaga aataacacca ttaaatcgat
   507421 ttcctacttt attaagcata tattcacact ttaaccactg ttcaacatca cgcgaagcat
   507481 catctgcacg acgttcagtc atagatagat gtgtaccaat ttcaagcatt tttttacttg
   507541 gttttttacc ttttttgttt aaaacacgtt taatagcgcg atgtactaga agatcagggt
   507601 aacgtctaat tggggatgta aagtgggtgt agtctttaaa tgctaagcca aagtgacctt
   507661 cattgttagg agtgtaaaca gcttgtttca ttgtacgtaa cacaatagtt ttgattatat
   507721 tttcatcatt tctaccttta gaatattcaa gaattttagc aaaatcttta gattctggct
   507781 gtataccacc ttcaagtgtt aaaccaatag tagttaaaaa ttggcgagta acctctactt
   507841 tttcaactgt aggttttgga tgaattcgat ataaaaaatc ttcattgtga tgatttaaaa
   507901 attttgctgt tgcttgatta gccattagca tacactcttc aattagttta tgagcatcat
   507961 tacgagaaca atcaacaata ttagaaattt taccattatt attaaacaaa atttttgatt
   508021 caatacgatc aaaatccatt accccacgtt taattctgga agttctaagt gatttgtata
   508081 agttatataa tgcatttaaa ttatccatta ctggtgcata gtacttggtt aaatcagtat
   508141 catgatgctt taaaatttga ttaactttag tatatgttaa tcgagcatgt gataacataa
   508201 cagcaggata aaacttataa tctaatagat taccatgagt atcaatattc atctcacaag
   508261 tcacacataa tcgttcaaca ccaggattga ttgaacataa gccatttgat aaaatttcag
   508321 gtaacattgg tacaacacga cgtggaaaat acaccgaatt accacgatca agagcatctt
   508381 tatctaaatc tgatccttct tttacataat gtgatacatc agcaatagca acaattagtt
   508441 tccaaccttt actggtaacc tctgcatata cagcatcatc aaaatcacga gaatcttcac
   508501 catcaatagt aactagcttt attttagtga tatcaattcg gcctattttg tcagaatcag
   508561 taactacagt tggtaattta gaaatttgtt caaatgctcc tagtgaaaaa tcaacaggaa
   508621 tactatttcg ataaagagca gaatctgttt ccatgccttt atccatgtag atacctaaga
   508681 tttgaataat ttcacctatt gctagacttt tcaaagttgg ggatctaata attttaacaa
   508741 tcacaatttg tttatcatga tgttctttat taatctttag aatactgata ttattcttaa
   508801 tacgtttatc atcaactaca acataagcat attttttttc aagatgtaga cgccctacta
   508861 cagttttaat gcttttgata actttgataa tttgtgcatc accccgttga ttaagtaatc
   508921 gcgcttctac tttatcgcca tgaaagacta attgcatttg ttttaatgag agtcttaagt
   508981 ctttaccacc tttgtctaat gcaataaaac caaaaccttt aggattggca attacctttc
   509041 cagttatcac accattttta gcactaaatt tatggtacac accatgttga tcgaaattaa
   509101 gttgttgatc acgaaccatg gctttaagac gatgtgatag aggttttttt tgatgataat
   509161 caatagttaa taaatcatat aattcatgta gtgtacgtga ttttttttca aaaaaactaa
   509221 ggatatattt ccttgaagga attgagttgt cgtacttttt tgattctttt ttataatgaa
   509281 aatctgacat taattactcg aatggatgtt ttaaaattag agtttgtgtt ctgtctggac
   509341 cggtggataa gatatccacc ggaagattag ctaactgctc aattttatgg atgtagtttt
   509401 gtgcttcaat aggtaaagag tcaaatgaat tagtaccaat ggttgaagtt ttccaaccag
   509461 gcatttcaat ataaactggt tttgcatctg tgtatccttt ggcatcatat ggcggtattg
   509521 taacttcttt gccatttaat ttataagcaa cacaaatttt aacacttatt aatgaatcta
   509581 aaacatcaag cttggtaaga caaataccag taacagcatt taaattaaat gaacgtttca
   509641 atgtaaccat atccaaccaa ccacaacgac gctgacgacc tgtagttgca ccaaattcat
   509701 ggccaactgt acctaatact ttaccaattg catcaccttt attagtggaa acattataaa
   509761 ttagctcagt cgggaatgga ccactaccta ctcgtgttgt ataagcttta acaattccta
   509821 gtacataatt aatatctgtt actccaacac ctgaaccagt aaccgcaccc ccagaagttg
   509881 tgtttgaaga agtaacaaat ggataagtac cttgatcaat gtctaataat gtaccttgtg
   509941 caccttcaaa tagtatattt tcatcattag caatatgctg atgaattttt tctgttacat
   510001 caataatcat atgcttaatt ttttttgctt gagatagagc ttcatataaa ataacttgat
   510061 aatcaacagg agctgtacca taatagttag tcaataaaaa gttatggtat tctacaactt
   510121 ctttaagttt tgaggcaaac aggattggat tcaataaatc tcctgcacgc aagccccgac
   510181 gagcaacttt atcctcataa gtagggccaa taccattacc tgttgtgcca atagcagtct
   510241 taccacactt tgcttctcga gcattatcaa gagcaatgtg atatggaaaa attaaggggc
   510301 aacctgggct aatctttaaa cgctctgtta cattaatatt agcaccttct aactccgcta
   510361 tttcttttaa taaagcagac attgataata ccactccatg ggcaattaaa cattcaacat
   510421 ggtcgtgtaa aatacctgaa ggaataagat gtagtacagt tgtttgttga tcaatgacca
   510481 aggtatgacc tgcgttatgc ccaccttgaa aacgcaccac gcttactgct ctatctgaga
   510541 ttaaatcaac tatcttacct ttaccttcat caccccactg ggtgccaata atcactacat
   510601 tttttgacat atcaattcct aactatttaa tattgtttaa aaatgacttt gagataagaa
   510661 tttcaaatca aatgaaaagc cagtagctgc tcttgatttt ccaaaagact taccaatgtc
   510721 gttataacga cctccttgcg ccaaagcttt agaataattt ttattataag ctgaaaacac
   510781 aacacctgta tggtattcat aggcctgtaa ttcgctaaga tcaaaaatag ctttaatacc
   510841 cttttcaagg agctgtttgt caatgataat taaatcttca atagctattc tagcttgttc
   510901 aaaatggcca aatattatca atgccttatc tagaatatca gaatccccct ctagttttat
   510961 caaatggata aataaatcag catttttaag cgtgttatta tttaagaata cagctaaatc
   511021 tggcattgat cgacgtgaga aaatagctct caaatgtgct actgcttgta ttgatatatt
   511081 ctcttgttct gttaaagaat caaaaatagc aacattaccc aagataagta tgactgaatc
   511141 aattgataat agctttaaac tttccaacat taattcgatt acctcaacat cagattcagt
   511201 ggcatctgaa ccataaagct cagctcctgc ctgaatagga gagcgtgatg cgtagaaatc
   511261 atctgctttg gtttttaaaa ttgaattaat gtagcaatat ttttcaaccg aatcgctacc
   511321 acgtttagca tcaatacgtg caatttgtgg ggtaatatca gcatgaactc ctagcatttt
   511381 accactatta ggatctaaaa acttgaatgt tttttcatca acaacatcat tagttaataa
   511441 gagtgaatta acatgttcaa ccattggggg aataactaaa ccgaaacctt tatcagcata
   511501 taaatctaaa agatgacggc gcaaggactc aaaaaccaag gcttgatcat tagtaagctc
   511561 ctctatactt tcaggcaatt gccacactcc cgtatctaat tatttaattt gtggattaaa
   511621 gtaacggaag aattccgtgt ttggattaag aactaaaata ttattttgat tagaaaatga
   511681 ctttttgtac gactctaatg aacgataaaa aacataaaaa tctgaattct tactataggc
   511741 ttttgcgtag ttatttgcac taacagcatc accctcacct ctaattttct cagaatctcg
   511801 ataagcattt gccaaaataa tagtacgttc tttgtcagct gctgccttaa ttatttcagc
   511861 tttctctgct cccttagatc taaactcttt agctactctt tgtcgttctg cctgcatacg
   511921 acgataaact gaattagata cctcttgtga taaatcaatt cgtttaatgc gaacatcaat
   511981 aatcttaata ccaaattgag caatgtcctt ttttgcaagt ctggcaatgt ttgccataat
   512041 ttcactacgt tcaccagaaa caacgtcagc aatagtacgt tttgaaaatt cacttttaag
   512101 cccagtttta ataatttggg ctaggcgatt attagttcta gctatgttac cacctgttga
   512161 tttataaaac tgctcagcat cttcaattct ccatttaaca taagaatcga caatcacatt
   512221 ttttttctcg cctgttaaaa atcgttcaga tggtgcatct aaagtttgaa tacgatggtc
   512281 aaattttaca atattattaa caaatggcat tttgaattta agacctggaa ctttctcaac
   512341 gcttacaatt tcacctaaac gtaatttaat ggctgtttgt gtttcattga ctgtatagac
   512401 tactgaactt aatactaaaa ataaaacagc aattagagct aaacctattt tttgcattat
   512461 ctacctcctc tatttcggaa aatatctcta acattactac taccttgatt gttttgtttt
   512521 attgatgatt cttgaatagt aacttgtgca tttgcttgct tagcattaat gagtttatca
   512581 ataggtaagt acatcatgtt attagtctta gagtcaacca taaccttgct ggtagtagcc
   512641 agtacgtttt ccatagtttc tcgatataaa cgctctttag taactttggg tgctttttca
   512701 tattcagcta aaatttgttt aaagcgtgag gtttcacctt ctgatttaga aactatttca
   512761 gatttgtaag cttttgactc ctcaagcata cgtacagcct taccacgaga ttttggtaag
   512821 atatcattag cataagtttg tgcttcgtta attaagcgtt gcttatcttc tcgagcttta
   512881 actgcatcag aaaaagcaga ttgtacttgt tctggtggtt gagcatcttg catattaact
   512941 gtggttatta ataaaccagt tttgtattta tcaagcaaac tttgagattt tattttaata
   513001 tcatcagcaa tattaactcg cccttcagtt aaaatataat ccatggtatt ttgaccaaca
   513061 atttgtcgaa tagcgctttc agagacgtga cgaagtgttg tgtctggttt gacaacatta
   513121 aataaataat cttgaacatt gtttattttg tattgaactg caaatttagc ttcaatcata
   513181 ttttcatctt tagttaacat taatgattca gatgaaacat tactaccaaa acgtcgatta
   513241 ttattaaccg tattacgata accaatttca gacgttctaa tttgttcaac attaattcta
   513301 tttaaagttt caattggata aggaatatgc caatgaggtc cttgagaagt ttcttcttgg
   513361 aatgccccaa aacgcagtat aactcctttt tcagcagggt caataatata aatacctgat
   513421 aataaccaaa taaataaaat caaaattaat atatatttca aattaccatt tgaaggtatt
   513481 ttaggtgtaa ttgtatttga tgatttctta ccatttaaaa aaccatcaaa tttatttttc
   513541 atatctttga ttactttctc taattccggt ggagtttgat tattgccatt ccaaggattt
   513601 ttattgttgt tgtcattcca agccatttta atttatgtgt ccaaatatat agttaaaatc
   513661 tggagttatt ttacccaaac taaagcaagc ttatgcaact aatagggcaa tctattatta
   513721 tggttatatg atgttaaaat aacaacattt gagagaatat acaattatca tgcaaaaaca
   513781 attagctctt tgtttattac ttgctttttt atctaacact attagtgctg gaagtttaat
   513841 actaaactgt aaaaataacg ttttactttt cccagaacaa atactctcaa ctgaaactaa
   513901 agatcttaat attcaagcaa attatagtga aatttacaaa ggtgatagtt attttttaaa
   513961 aggcaatgtt tcactaaatt caagcactta ttttctaggc gctgatgaaa tcagtattaa
   514021 caaacctagc aaaatatcaa cagctactgg ctatgttaaa tttcaaaaca acgaacttat
   514081 gctaactggt gataaagcta tgattaaaaa acaaggtgaa atgatttata caactttaaa
   514141 tcaagtaaaa ttctactatc caaacttaaa aataaagggt cgtgcacaat ttgtaactca
   514201 tgatggtact gaacaaatat ttaactcagg tagctacagt ttatgcccac taggtaattc
   514261 tgattggcaa atgaaggctg ataaaatcat attgaattca acgaccaata aaggtatagc
   514321 aaaaaatgtt acgattgaat ttttagggat aactattttt tattcccctt atcaagaatg
   514381 ggtattgaaa ggtcgtagtt ctggattttt agcgccaata tttggtagtt ataatgaatt
   514441 aggtgttagt ggaggtagca actaccaagt taaaattcct tattatttta atattgctcc
   514501 tgatcgtgac tttttcttaa ttttgaacca attatcaagt cgtggtagtg tatttgaagg
   514561 taaatatcgt caacttatca ctgacaataa ttatttaggt aatgggcgtt ctgagattga
   514621 aggtcattat ttattaaata aagataaaat tactaatagc agacgttggc tattaaattc
   514681 aaaattagac ttatcactaa acgctaaaac tgatttaagt attgtcacta gtcgagtatc
   514741 agattcggat tactttaaag aaattgctca tagtaatact tcggattcaa aattacgatc
   514801 ttatgttaat ttatcctaca aaaaccagaa aaaaaattta actatgtctt tttttattga
   514861 atcagaacaa cttattaaca acggaagtgc ttcgtacaca cgtgtaccag agttatctat
   514921 taataaaaaa tataaaggtt tagatggacg taatgttgtt ttctcattaa ttagtacaaa
   514981 atttacgcac aaaaactcaa atactacaac caataaaacc gggattcgaa ctcatgcgca
   515041 gacaaaattt agtcgctcat taaaaactaa taactattca attaccccaa gtttgaaatt
   515101 atcaacaact aattatacaa tggatgatgc tgttcatcaa gaacgaaata ttgttagttt
   515161 tggttttgat tctaaatttt tcttagaaag gagggtgttc ttatttggta cacatttaac
   515221 tcaaacctta accccaaggt taggatacaa ttacacacct aaaaaagacc aaagtacatt
   515281 gcctaatttt gattctgatg ataaaaataa tttatacgaa agtttgtttt ctggacaaaa
   515341 atttacaggt atcgatagga ttgctagtgc taatgatctt atttttggtc ttgagtcaga
   515401 ctttattaat gaagaaacag gtggtaccta tttaagttta aaaatagccc aggcatatca
   515461 atttgatgac atgagtatga acagaaatgg cactttagtt agtcaaaaaa aatattccaa
   515521 tgttgccatg tcggctaatt taacgatgcg tgatttttct tttaataatt cactacagta
   515581 taattcaaga actaataaaa taagtaagcg taatagttca attagtttta ttataaattc
   515641 tagaaagttt ttaactttgg cacattatgt tgataatggc aataattcag ttgaattata
   515701 tagcgcttat ccattaacac aacaaacaca tgtgtttgct ggtattaatg gatctattag
   515761 taactcaatt attaataaag aaaccatagg tattgcttat gaatcttgtt gttgggcggt
   515821 acgtttagcg tattttaaag agtatttaaa tgaaaacaat tatgattatg tggctaaatt
   515881 tgagctagta ctaaaaggat tagctaccac ttcctcaaat ttatataaac gtttaaagga
   515941 agatatacct aattattcag tcaatcttaa tgatttttaa aatgaacaaa actttattat
   516001 taatttgtgt attttcattt aatatatttg ctatacctaa tagtattgtt gctattgtta
   516061 atgatgattt gattactttt gaccagatta gtattgatat taaacccaac tatactaaag
   516121 cacaaaagtt gactttagtt aatcaacaaa tagatttaat cttgcaatta caaaaaatta
   516181 aacaactaag tattgttcca aaagagaatg tgattaatag catgttaggt aatattgctt
   516241 taaataatga tttgagctta atacaattgc aatctttgcc tcaatttgat aaagttatta
   516301 accatgtgaa acagaattta tcattagaag gtcttaaaca ttttattatt gaaaatctta
   516361 atattgaact tactgatgtt gaaataagta agcaattatc taaaacccct aatcatttaa
   516421 acaagttaga gaagcaaata agaatagcgc aaatcaccat taactctact aaccaagtag
   516481 attcaaatcg tttaattaag gatcgattga ttgatttaag tgagaaaatt aataaaggtg
   516541 attcattttc tattttaaaa aaaatttatt cgcaagataa tttttataaa aatgacagtg
   516601 aatctatttg gcttaattta tcaaaattac caaaagcttt tcaacagagt ttaaaaggcc
   516661 ttttagtagg tgagatatca cagccattta aaataggaca agtttggagg attgttaaaa
   516721 ttattgataa acgtagtgtt gacaattatc tagtcgaact taaagctaaa ttaatacgcc
   516781 aaaaagaaga tacttacttc tataattggg ttaagaaaat aaggaaagaa gcttatatta
   516841 agatttttga caataagtta taaatgtcta aatcaatcat cattactgga tttcacgcta
   516901 ttcaagcaca gttaaaattt aaccctaaat atttaattaa gattttcata ctaaataaac
   516961 gatgtgataa gcgtttaaat actcttatcc ttgagattaa taattttgat attaacattc
   517021 aacagtgtac caaagtacaa ctagataaat taagtaatta tcagactcat caaggtattg
   517081 cagctgaaat attattacct atcctaccta accaatgtga actaattact tacgtgtcta
   517141 aattagataa tgctagttta atcttaatac ttgattctat tcaagatcct aggaatttag
   517201 gcgcttgttt gcgtagtgct aatgcagctg gggttgattg cgtaataatt aataaagatg
   517261 gttcagcgtc tattagtgca ttagtacaca aaacttctgc aggtgcgatt aatcaaataa
   517321 aaattttcca agtaaccaat ctgtcgcgta ctattaaagc attacaacaa caaaatattt
   517381 gggtaattgg tttagatagt tctgccaata ctctgattta tcaaatagat ttaaccacac
   517441 caaatgctat tattatggga tctgaaggct ttggacttaa aagattaacc aaacaatctt
   517501 gcgaccaact ggctaaaatt cctatgcaag ggaaagtaga aagtttaaac gtttctgttg
   517561 ctacagggat aacacttttt gagataaata gacaacgctt tctatagttt taggcatgta
   517621 aatattgcac ttatatttaa tttagcaatg acaaaattaa ttttgtctta ctgtcgttaa
   517681 aatagctaat aggatataat acaacactca atgaaatgac tattataaaa agtaatttca
   517741 ccttatcaaa ataatattga tcacactccc gtttgttatg tttgaaatgt gcctttaaac
   517801 ctagattggg aaatattctt catattatta atttaattga atacgatgtc cccatggtac
   517861 atttttattt cctttaataa gccacattac tggatagatt ggttcatatt ttggaaattt
   517921 tcctttagca tcagtaaagt aaattaacac gctagaagca atttcttgcg tgttaacatg
   517981 atcaaataca ggattaaaat tagtaccttt gccaccaccc accaatgata ctggaaatat
   518041 taactcatcc caaacttcaa aacgccatat cagttcttta ctgacttttt catcacaagc
   518101 aattaatgta attgtagcgc gtatattact tttaatggca ttaatttcta ttataaactc
   518161 gttaatctca ttttgagaaa ttgagccaga agtatcaata gcaacagtaa tattaatttg
   518221 gctagatcta agtgatggca atatggcatt gccactacga cgtgatggtc tagcatagga
   518281 aaaatcatca cgtacaaaac taaacatata ttgtgacaat aaagattgcc aagaaaactg
   518341 aggctgaagg aaaaaattaa ttaatttaat aaattcacca tttaattttc ctgcttgttg
   518401 tgcaagttgt atacttgaag caagattttt ctgccattta ccacttaatt gttgaatttc
   518461 aacaggtgtt aaagggttag gcttatttgc caagtaaaaa gaatttgaat tattattact
   518521 attgtcttgt aaattattct ttggactatc atcatataaa tgttgatcca taggtttagt
   518581 atcaatacta tcatcaacca ttgggtaaat ttcttctgca atcatacctt gatatttatg
   518641 gaaaatagac agtccaggtg ggggatgaaa tccttctttt accaaaagcg gattaatggc
   518701 aaaatcacaa gctaaatccc atttatgttt aagccgatta ccacgacgag aaaagtgcat
   518761 tagtgcacaa tgtaggactt catgaataag aataaactta gtttgatgat gatcaagctg
   518821 gttaataaaa tttggattgt agtaaaaact tttagcatcg gttgcactag ttttacacca
   518881 agatccagca gctttaagtg gcaatctaag cactaaatta cctagaaaag gttggtcaag
   518941 aataagttgt gttcgagctt tagtcaattt tgctttaact acttgtaaat caagcttatt
   519001 aatattattc tcaatcataa tatcttcatt aataactgtt ccttgtgata cacactaaat
   519061 gtcactactt ttacaaatta aattatcaaa tattagtcaa gcataacatt agaaattgta
   519121 tttgcccaat cggcaaattc agggatagta aaaatatctt caccaatggc tcgttgcatg
   519181 tctaatacta gcataacacc taactcattt cgaggaaagt ttttagcaaa attaagaata
   519241 ttaccccatg cttttttagc atgattacta cctttaagac tggttgctct acctactagt
   519301 gctgcacaaa ttacatattg caaatcaagt tcttctggaa ttgaaacact ttcgccgtta
   519361 atgatagaat caagattagg aaaatcagat atgtgtttaa taaacgtggt aatttcaact
   519421 cctgctattt ttccaacgca agcactagca gcttgcttaa ataaagacaa atcagtacca
   519481 aattttttca gggctctatg tacaaactcc caagtccttg gcgaaggaaa ggcagttgga
   519541 ttgtgtttag aattaaactc aaacaaatat tcagggcgat aacgtaaaaa gccaataata
   519601 cgttcatcaa tgttattttt atatgcccat gtcacccaat catccaaatt aacatccagt
   519661 tcgaaatgcg aaaatcgatt tgccaaaggt gcaggcattg aataagtaat acctctatca
   519721 ccttgacgat tacctgcagc aaatattacc caacctttag gtacagtata atcacctaaa
   519781 caacgatcaa gaatgagttg ataagctgct gctgatacgg ttgggggggc tgaggtaatt
   519841 tcatcaagga ataaaatacc ttgctcgcca tgacgctttg aatcgggtaa taatgaaggc
   519901 actgaccagt caactaaatt gccattttta aacggtatac cccgaaggtc actaggttcc
   519961 atttgtgata agcgaatatc aataatatta actttattgt tacttgctat ttgaaagata
   520021 atttgagact taccaatccc tggtgaaccc cataacataa caggtgtatg ataaccttga
   520081 attactgatg ttaactcttt attgagaatt tcacttactt ctttaggacg catgaatact
   520141 tataaattat ccaaaaaact tccattttac agtaataaaa gataaaatta cttgatatga
   520201 ttaccgttaa ctctacttca gaaactttat ttaattttcc ttgtgactat tctattaaaa
   520261 tatttggtaa aaattgtgaa aagtttcaga atacaatttg cactattgtt gaacgtcaca
   520321 ctcacaaatt aaatcccaat aaaataacaa agaagcacag ttctaaaggt aattatgtgt
   520381 ctttcagcat tcgtattatt gccaacagta gaattcaatt agattccatt aatcaagatt
   520441 taaaaaactg taatttagtg tcttatgttc tataaattat tatgcgtgtt atcaatttag
   520501 ggcgtcaaga ctatttaaac atctgggata agatgaaaac atttactaat actcgtgata
   520561 aaaataccaa agatgaatta tggattgtag aacacaatcc tgtatttaca caaggggttt
   520621 ctagtaaacc agaacatatt ttatccaata ctgatattcc tatcgttcaa actgatcgtg
   520681 gaggacaagt tacttatcat ggccctgggc aagtgattat ttattgtcta tttgacctta
   520741 aacgtcttgg catgggagtt aaaagaatta ttgaaattat tgaaaattca ataattgact
   520801 tattgagaac ttacaccatt aaagcacatc taaaatccgg agcacctggt gtatatattg
   520861 ataatgctaa aattgcagca cttggtttaa ggattaaaca atcaagaatt tatcatgggc
   520921 tgagtcttaa tatagatatg gatttatctc catttatcca aattaatcct tgtggatatc
   520981 aaaacctgaa agtaacacaa ctttgtgatt taacggatag tagagatact ttaaatatta
   521041 ttgctaaaaa acttagccaa atacttatta attatgtttc aagaaataga cattaaaagt
   521101 ttaaaaggaa aatctaaagt ggcacgctta agaattaaac ctgatgttaa tagaacagtt
   521161 attagaaaac caaaatggat acggaccaag catatttttg gttcaaaagt tgatcaacta
   521221 aaaagcacgc ttcgggcgca gaaattattt acagtctgtg aagaagctca atgcccaaat
   521281 ttagttgaat gttttaatca tggtactgct acttttatga ttatgggaca aatctgtaca
   521341 cgtcgttgcc cattttgtga tgtcgctcat ggtaaaccca gaacgcttga tatagatgag
   521401 cctaaacatt tagctgatac catcaaaaag atgcgactta agtatgtagt gattacttca
   521461 gtagataggg acgatttaca tgatggaggt gttcaacatt tcaaaatgtg tattgataat
   521521 atcagattaa gtacaccaaa agttaagatt gaaatcttaa ctccagattt caaaggtagg
   521581 attgataaag cacttaaggt ttttaaatct tgtccgcctg atgtctttaa tcataatctg
   521641 gagacagtgc caagcttata cccaaaagtt cgacctggtg caaattatga gtattcatta
   521701 aaattacttc aaaaatttaa acaacaacac cctcttgtta ttagtaaatc aggattaatg
   521761 ctaggggttg gtgaaagtga aaaacaagtt atcaatgtgt taaaggattt acgcagacat
   521821 aatgtagata tgcttactat aggtcaatat ttacaaccaa gtaaatatca tttagctgtt
   521881 gaaacatata ttcatccgaa tcaatttgat aagtatagaa aaattgcact taaattaggt
   521941 tttattagag tcgctagtgg acccatggta cgttcttctt atcatgctaa tttacaaatt
   522001 aaaggtaaat taataattta gtgattataa aaagaataat ttatatcata aattattctt
   522061 atctgttttc tttactagct tattaatacc taattcctca ctactaagtt taaccttatt
   522121 ttttctacca agaactgttt ttatccattc tttagggtct ttattttcct tttcagattt
   522181 tggctcttca acattgtatt tcgaatctgc atctttattt tcaggaagaa gacccatatt
   522241 aaccgcaata tttctacaag tagcttcgcc agcagataaa gttcctaacg ggattacaat
   522301 tagcgttagt atagtagaaa ttagtacacc aaataataat gaaattgcca taccttggaa
   522361 tataggatct gataagataa cactagaacc accaaccaat gcaaatgcag taatcataat
   522421 aggccgtgtt cttgaagagc atgaattaat tattgcatca aaaaacggta tacctttagc
   522481 atattcttga acagtaaaat caactaataa aattgaattt cgtacaataa ttcctgctaa
   522541 tgcaatccaa ccaatcattg aagtggctgt aaattctgca tctaataacc aatgacctgg
   522601 gacaataccc aataatgtta atggaattgg tgccataata acagctggaa taataaagct
   522661 accaaactgc cacacaacca acatataaat tacaactaac gctatagcaa atgtgctacc
   522721 catgtctcga aaagtctcat aagtaactgt ccattcacct gtccattcaa aacttggaat
   522781 ggtttgatct ttaggtggtc ccagatattc accttgtaat tgtttgccat caatcgtttg
   522841 atatttaagt agcaagtcat ctacacctaa cattgcataa attggtgcac ttaggcgacc
   522901 tttaggttcg cctaatacat attcaatatc tgctaaatct ttatgaaaaa ttaaatcatc
   522961 ttgcttttta taactaaatg aacctaattc tgaaattgga atcaatccac catgctgaga
   523021 aggtacaggc aattgagtca aataagataa ttgagagcgt ttagatagcg gtatttgtaa
   523081 acaaatacgt gaaggttcaa gtgcattttt taatctaatt gtacctacat taaaactact
   523141 catagccatt gaaagtgttt ctttaatagt cataacacta acaccaaatc gagaagcttt
   523201 tgctgtatct acttgaaagt caataacagg atacttatca cgtataagat tatcaacatc
   523261 tgtcattgta cccgattctt tgaataattc tgttaagtca tttgctaatt tacgacgagt
   523321 ctccttatct ggcccgtaca cttcagcaac aacaggactt aatactggag gaccaggtgg
   523381 catttcaata acagcataat tagcacctac atcttctaca atctgtttaa tcaatgttct
   523441 tgcttctaag gcaatttcat gactagaacg agctctctct gatttttcaa ccaactgaat
   523501 ttgcaattca ccttctgaag gagattgtct taaataataa tgtcttacta gtccgttaaa
   523561 atcaaaaggc ttggcagttc ctgaatagga ttgaatagca acgacttctg gtacattgcg
   523621 caatacttgc gccattttat gtaaagttga agctgtattt gctagtgctg taccatcagg
   523681 catatttaaa attacaccaa attcagactt attatccaga ggcaacattt ttacaggaac
   523741 taaagtagta tagaacattg atattgacat aaaaaaagca acaatcaatc caatcaaaaa
   523801 accccaacca tatattttta tattgaataa tttagagatg gttgaatgaa aaaatgtaaa
   523861 cataactttt gcttcttttt cttctttttt atgcattttg tgtagcacat tcaaaggcgg
   523921 tacaaatatc attataaaat aaggggtaaa aacgaacgct gcaaacaatg aaaacatcat
   523981 tgcaaccgag cctaatatag gaattggagc catatatggc cccatcattc cactaactgc
   524041 tgccataggc actagagccg cgactacagt aaaggttgct aaaattgttg ggttaccaac
   524101 ttcacgcact gcgtcaatcg cggtaccaat agtaatttta ttatcaatca accatctcct
   524161 atagatattt tcggtgacaa caatagcatc atccactaga ataccaattg agaaaatcaa
   524221 agcaaataaa ctaaccctat caatggtcat gcctaaaatc cacgcagaaa aaatggtcat
   524281 caataataca actggaatga ctaacgttac tacaatagct ggacgaatac ccaaggcaaa
   524341 ccatacaagc agagtcactg cacctgtagc aataaataat ttcttaatta aaacatttac
   524401 cttatctttt gcagattttc cataatctct ggtgacacta atttctacgt tatcagggat
   524461 aagtttgcct tttaattctt caactttagc aagaatattt tcagctactt ctacgccatt
   524521 agtaccatat ttttttgcaa tagcaattgt tattgcctgt tcagcagtag cttttttttc
   524581 tgttttattt gcctttcctg tataataatt aaccatatgt tcagcatctt ctggtgcata
   524641 atacacatca gctacatcac gcacataaat tggtttacca tcatttactg taattaccaa
   524701 gttttcaata tcttccactt tactaaagaa atcacctgaa taaacctcca tctttaatcc
   524761 atttagttca atatttcctg tgtgtcctcg tacattagca ttaccaatag tactagcaat
   524821 ttgctgaata gaaatatcat gtccagctaa acgccctgga taagcatcaa tatgaaaaat
   524881 ttccttacgc ccgccaacaa caaagccatt attagtatct ttaacttttg caagctgctg
   524941 taacagttct aggcctaaag aacgtaactg tccgtcatca agtgattttg accaaagtgt
   525001 taaatttatg attggtacat catcaatttc tttaggttta atgagtggtt gcttagcacc
   525061 cgggggcata aattcaagat ttgacaacat tttgtcacgt actttgataa tagaggtatt
   525121 catttcttga cccacatcaa actctacagt aataacacct ttgctcttat cactaacaga
   525181 ataaacatgc ttaacaccta aaatatttga cattaaacgt tctaaaggct taataataat
   525241 atttgacact tccttagaag aagcgcctgg atattcaaca aataagtcaa taagtggtac
   525301 agaaatttga ggatcttctt gccttggggt tgaaattaaa ccaataatac ctgcgcctaa
   525361 catagcaaaa aatatgataa tagacagtga agaggtaata aaagctttag taagctttcc
   525421 agcaataccc atctcaaact ttctattcac cttatcgatc tttacctgat caacatgact
   525481 tttgtttgtc ataatgtgtt aaatacccat acctgaaacc attagaatgt ttggattaga
   525541 aacaattctt tcaccaattt ttaaacctga tagaacgctt tttttattct ttccaacttg
   525601 ttctcctaaa cgtataaatc ttaactctgt tttattggtt aatgaattaa caacaaacac
   525661 acttggtaat gaagatcgcc acataatagc aatttcagga atgactggcg ttaatacgcc
   525721 agaatctgtt tcaaaaattt ctacttctgc atatgctcct gataatactg gaacattagc
   525781 cggtaaatca aacttaacct taacactatg tttaacatta tctgcaatag gataaatttg
   525841 tgaaagttta gcatcaacta caatattagc aatatctaat ttaatacgat atgttttgtt
   525901 aagtttaaga cttctaacta accttgaagg cacattcact tctacttgaa gatttttaat
   525961 attagcaaat tttatcaaaa tttgaccagg ttggacaaca tcccccttat taatattttt
   526021 agccacaata acaccatcaa atggcgcact cacattagca tcttttaagc gtgattcagc
   526081 ttgctttaaa tgtaattcag cttgcttaag tttattctta gcctgctgat agtttgtgta
   526141 tctagaggtt ctattagcaa acttgtcaaa atctggatta ccttgacctg atatttttaa
   526201 catagggtca gtaaacattg aaaacatacc tggtacacta ccaaacatac cacctgagtt
   526261 tggcgataca attgattgtg aatattggac ccctgcattt ctaagcgcct cactagctga
   526321 agcaattgct gcataggctg aatctctttg tgcttgaatg gactcttgtt ctaatgtgac
   526381 taaaattgca ccttttttaa acatatcccc ctcttgaccc ttaatgttta atacatcgcc
   526441 agatacctga gcaaccaaat taacacgcga agaagaaata actgaaccac ctaaaagcgc
   526501 tctcttatct agtgatatac cccttacagc ttgaatgtta taaacagatt caaaattgtt
   526561 aatattttgt tttgtacttc cttttaaaga catattaagg gaagtaattt gtgctttaga
   526621 aggtaatgaa gacatcaata caatcgatgt gaataataag attaatgtat gcatagtcac
   526681 cctgttttta aaaagtaaaa aaataaactt tatcgaagat tttatatgat taaaatatac
   526741 tatatctatt attttccatt tataaaatgg gtaatataat tatatcttat taatacgagt
   526801 atttattttt aaataacttt atttacttta atgaataaat tttacttaca taaaaacctc
   526861 acaatattta tttaatgaca actattgctt tcaccgttgg agaaccatct ggtattggac
   526921 ctgatttagc tgttatttac gctcaaataa aatcaaataa aaatcttttg ttatttacag
   526981 atccagatgt tttattaaat cgtgcaaaac aacttaactt aaacataaaa attattgaag
   527041 ctgaacaagc tggttcaaat tatgaactgg ctgtctatcc aattaaagtt aatacccatg
   527101 tagagtgcgg tattttgaat aaagataatg cacaatatgt gttaaataca cttgattgtg
   527161 caactgagta ttgtcttaat tcacgatgtg atgccttagt tactggtccc atacataaag
   527221 gtattattaa ccaagcagga ataaatttta caggtcatac tgaatattta gctaacttgt
   527281 ctaatattga taaaacagta atgatgttgg caacaaatgg cttgagagtt gcactagcaa
   527341 ctacacatat gccactttca gatgtgcctc aaaatattac cacgcaatct ttgaagaaaa
   527401 ccattagcat tattcaccaa ttcttgttaa ataatggtgt caacacacct aaaattgttg
   527461 tatgtggttt aaatccgcat gcgggagaaa atggttattt aggtatggaa gagattgaaa
   527521 ttatcaatcc tttaattaaa gaactaaata gtcaaggata caatcttgtt ggtagtatac
   527581 ctgctgatac agcctttaca cctaattcac taactggtgt tgattgtgta ttgagtatgt
   527641 atcacgatca aggtttaccg gttctaaaaa cattaggatt taaaaaagca gtcaatatta
   527701 cactaggctt accttttata cgaacttcgg tagatcatgg tagcgcgctt aatcttgctg
   527761 gtactgggaa tattagcctt ggtagtttga atactgctat aaattatgca caaatgctag
   527821 tcatcaatca taaaaaattt aaaccaacaa aagttgtatc tcttgataca taaagctcgt
   527881 aagcgttttg ggcaaaactt tcttattgat aacagaatta ttgaccgtat tatcgccact
   527941 atctccccaa agcgtaatga taatttatta gaaattggtc ctggacaagg agccataaca
   528001 atacctttat taaattatgt taaccaattg aacgttattg aaattgatct aaatttgatt
   528061 tcaattctag aatcacttga atactctcat ttaataattt atcaaggtga tgtgcttaaa
   528121 tttgatttaa atatcttgcc tatgccaatt aggataattg gtaatttacc ttacaatatt
   528181 tcttcttcta tcctttttca tttgattgaa aatttagata aaatacaaga cataactgtc
   528241 atgttacaaa aagaagttgt agaaaggatg ggggcaaaca gtggctctaa agtatatgga
   528301 cgtttaagcg tcatgatgca aacatttttt aatattaata tgatttttac tgtaccacca
   528361 gaatcattca atcctgtacc aagagtagat tctgccattg tatatttaaa acctctagca
   528421 caaccaaaaa ccaaaaatat taaggtattt gaaaaagttg taaaattagc attttcacaa
   528481 cgaagaaaaa tgttaagaaa tagcttaaaa tatgtattaa cccaaaaaca aactgacatt
   528541 gacttatccc ggcgtgctga aatgctaaca gttgatgatt ttatcacctt aacgcaagac
   528601 tatgaaaaac aacattgaaa taaagattaa agtaacttat ttagagagcc aatcagatat
   528661 ttatgcaaat caatatatct atacttacac cattacaatt actaataggg gtaacgttgg
   528721 tgtacaactt ttaacacgtc attggcgcat taaagatgaa actgggcata ctgaagatgt
   528781 gattggaaaa ggggtaattg gtcaacaacc tcacttatcg ccaaaagaat cttttcaata
   528841 ctcatcaggt tctattatta aaacccaaac tggctctatg aaaggttctt atggtatgat
   528901 taatgatcgt ggagagcgtt ttaatgtgaa gattcctgaa tttatactta gcaaacctta
   528961 cactttacac taatgtcaga ctatttaata ggagatgttc aaggttgttt tgactctttg
   529021 caaactttgt taaaaaaaat taaattctca agcgataaag atcgattgtt ttttttagga
   529081 gatgtggtta atagaggtaa acaatcttta gctacattgc ggtttattaa agacttaaaa
   529141 agtaatgctt taatggtttt aggtaatcat gattttcatc tattagcctg cacattaggt
   529201 cgtaaaaatc ctaataaaaa agacacattc actgatatta ttaatgctca tgatgcaaac
   529261 ttattgcttg attttttgaa gaatcagcca ttagcaatta agcacaaagg tgttcttatg
   529321 attcatgctg gcgtgccacc aagttgggat attgatagaa ctcttaaaca atctagacag
   529381 gttcaaaaac atcttcaaag tgttaatgtt tcacagtttt taaacaaaat gtatggcaac
   529441 aaacctaata tctggtcaaa agatttaact gaactagaac agtgtaaata cactattaat
   529501 gctttaatgc gactacgctt ttgtaaatcc aatgatcagc tagaatttag ccataaaatg
   529561 aattatacac atccgccaaa aggttttaaa gcctggttta tgcataaaaa tagattatta
   529621 aaaaataccg atattttttt tggtcactgg tctagtttat caggtgttaa tcaaacacat
   529681 atttattcga tggatcatgg ttgtatctgg catggacatt taagtgctat taggctaaag
   529741 gataaaagaa ttttctctgt tagttgttaa atctctactt gaccttcaaa cacaaattgt
   529801 gcaggacctg ataaaaatat atgcccacct tgcgtgtatt caattaaagc atcaccccca
   529861 cttaagtgaa caacaacatt tttttttaat aaaccttgtt caacaccata agctactgct
   529921 gcacaagctc cagaaccaca agctaaagtt tcctcagagc cacgttcata aacacgtagg
   529981 ttaatttcat gagtattcaa aatttgcata aaaccaatat tagcttgatt gggcaacaat
   530041 tcactttgtt gaattttaag tgcaatagta ttaacgtcaa tagtattaac atctttaact
   530101 aacataacac aatgaggatt accaattgag atagcgccta agtcaaatcc ttcaatctga
   530161 taatattcac tttgttgcgg tactagaagt ggtatatcag ctggattaaa acttggtttt
   530221 cccatatcaa cacacactgt gttatcgtca tttagatgta aactaatgat attagaacga
   530281 gttttgacag taattggatt actatgagtt agattcttat aattaacaaa acgagcaaaa
   530341 caacgtgcgc cattgccaca ttgttctact tctgaaccgt tagaattata aataacataa
   530401 cgaaaatcaa cacctcttat attactcgtt tcaactacca atagttggtc aaagccaatc
   530461 ccaaaagccc gattagctaa atttgttatt ttcttagcat taaaggtaat atcaccagca
   530521 agattatcaa ccaccataaa gtcgttgccc aacccatgca tttttgtaaa attaattaac
   530581 atattttata tattatccac ttataatttt caaggttaaa aaaaattaag ttctaattaa
   530641 atgttatttg atgtaactgg tctaggtgac accaatcaag aaaaataata aattttgatg
   530701 aagaaattta tcaagaaaaa gttattatgg ataaaaatat aaatgcgtaa gctgtttaaa
   530761 atgaagttaa ggcgttctaa acgtctcttt gctaaatatg ctaaaaaaac acatcgtaag
   530821 aattcaactt ttgaattctc acacttgtcg agggggtggt ataaaacttt aacgatatat
   530881 tctgttccag atatgattga tcatttttaa tgataggtat tattctttct ggtctactcg
   530941 gggttctact gttggtggat aatgtccatc aggcttctag aaatcgtagt tttcaatctt
   531001 atatgtctga taatgctcat caacgagagg ttaatgacct tcgtaaagct ggtctaaatc
   531061 ctatactatc ttctactaga ggtgctggtg cttctactcc ttctgggagc tattactact
   531121 gtagatagtc ctactaattt tgttgtctct gctaatgaaa atagtactga aatgctacta
   531181 ctgtctagtc aaagctgatc tagtcggttc tcaaactaaa aaagacaaat accgaagtga
   531241 cttactccaa caacaaatac ctgaagccat agctaatagt gcaatgtggt caagtcaata
   531301 agcaaaaaca atgaaataag tataatatgg cataggtctg gttggagggc ttgttcctag
   531361 tattggtcta attatgaatc gagtacgtcc taaacctaaa aaacctgttc ttgataaata
   531421 ttttaaaaaa tatcgtaata actttaaata aacagtcgct ctgctcttta atataattcc
   531481 cccaaaaaaa gctgggaggg tttgaaaaaa tttcaacctc gcccctaatg gggtagagtt
   531541 ttttcaaatc tctatatgct ttagcatact atcatgtata cttctttcat gaaaaataca
   531601 aaaataatct actcaatgaa gttgtttcgt taataaaaca aagttttaaa gatgagtgtg
   531661 atattaacaa tatactctct cgttatgatt tatctggatc tttaccagat cctaatccta
   531721 aacaacctca atatagcgac tttactgatg tgaactttca aggttctgct aatttagtcg
   531781 ctgaaatgca aatctacttg ggagaatttg cctttggcat ctcgtgaaaa atatgattct
   531841 tttgatgata gagaaatctg aagagaaacc cgcttctgac gatgatgttg gaagcaaagc
   531901 ccagttatat acttgatgtc cattgtcaag aaaaccaaca aaaatatcaa ccaatattat
   531961 cctaaagaaa gaaaaacttt acaactatta cctttaatga gattgactat ctacttagtt
   532021 ctaaatattt aagaatttat catgaatatt tacaaaaacc aaaagacgtt agacatacct
   532081 acttacagtt atagattcta atggtgttta tttatgcttt gggatttttc ttaattacta
   532141 ctagtatttt aacaactgtt catgaattag gtcatttttt agtcgctaaa aagtttaatg
   532201 tcaaagtatt acgtttttct attgggtttg gcaaaatttt gacatcattt aagtatggcg
   532261 aaacacaata caccttatgc gcactccctt taggtggctt tattaagatg cttgatgaaa
   532321 acgaaacttc agtagagaga tcagaaaaac atcgtgcatt taatcagcaa aacgtttata
   532381 tacgtatcat gattattgtg gctggaccaa ttgctaattt tattttagct attattcttt
   532441 ataccgtcgt ttttgctatc ggtgttactg gtgttaagcc tattgttggt acacttgaaa
   532501 cccctagtat tgcccaacaa tcaggcatta aaaaaggtga tcaactattg agtattaatg
   532561 gtatttcaac accaactatt agtgaattct caatgagttt tattcaatca ctaaataaga
   532621 cccctcttta tattaatgtt atttctgata cttcaaatct cagaaaatta aaacttaatc
   532681 tatctggtga ttttttatct aatccagaac aaggtattga tcgttactta ggatttaaat
   532741 ttgctatgcc taaacttgag gcaattattg accaaatcat gcctaattca gctgcctcaa
   532801 tagcaggtct acaaataaac gataaaattt taagtgaaaa tcatactcat attgactcat
   532861 ggagtgattt tgttaacact gttcaaaaca atcccaacaa aaagattaat ctacgagttg
   532921 agcgtgatga taatattata aatataacat taataccaaa aattgagaat ggtttagtca
   532981 aagcaggtgt taacgtttta atacctaata actatttaga tgagtggctt gtattagtta
   533041 aaaaaaatat atttgatgct tttatagagg ctaataataa ggtttatcaa cttatcttac
   533101 tcaacttaag aatgattaaa aaaatgatta taggtaatgt atcacttgat caaattaatg
   533161 gccctattag tattgctaac tatgctggta aaagtgccca agttggtttt gtgacattct
   533221 tatctttttt agccattatt agcattgggc taggtttgct taatttatta cctattccat
   533281 tattagatgg gggacactta tttttctatt taatagaact tattaaaggc tcagctgtta
   533341 gtcgatcgtt tcaacaagtt ttaacaagat ttggcttgtt tgttattata ttaataacag
   533401 ttgttgctct gtataatgat ctgtcacgtt tattgtaatt tatcaaagaa gatatgagaa
   533461 aaatcattac caagcttatc ctagtagcaa gcatcttggt ctgttcgatt gcatcagcaa
   533521 catctatcaa aagtattgaa attttaggcc ttaatgttat ttctagagat tctgtcttaa
   533581 gttatcttcc agttgaaata ggtgatgatt ataatagcca agtatcaaat caaattattc
   533641 gatccttgta caaaactaat ttttttaaag acattgaagt ttctcaagaa gctaaaattt
   533701 taaaaattaa gttaacagag aatccacata ttaaatacat taatgtaact aaccattcaa
   533761 ataaagtgat tgaagaaaaa ccattaaata aaattttaaa aaatatggga ttttctcaag
   533821 gcaagatttt taataaaaga caatttgata aattaataac ccagctaaag gatacataca
   533881 tatcaaaagg atattatggt attaatattg acaaaaatat tgatattgat acacaaaata
   533941 gagtaagtat taaacttgat ataaatgaag gtaaagtagc aaaaattagt tccatgaaaa
   534001 ttattggtaa tcatgttttt aacgaaatcg atttattgaa cttatttgaa attggtcagt
   534061 ctgatttttt tattatcaat ttttttactg aaaaagacca tcattctaaa atagcgttag
   534121 atgttggtat tgaatctatg aaatcattat atactaatgc tggatatttt aattttaaaa
   534181 ttgataaaat caaaacaaat ttatcagaaa ataaacaaaa tattgacatt actattcaaa
   534241 tcagtgaagg ttctaaatat aaaattggca gcataaaatt tacaggcaat ttacttagcc
   534301 atcccattga aaaacttagg aaattattaa gttttaataa aaatgacata tttaaccaca
   534361 aaaaaatgat gcagggctta caaaatatca ataatgtatt taccaaccaa ggctatgctt
   534421 tttctgatgt caaagttaga atatcagaaa acacaagcac acatactatt gatctaaata
   534481 ttgacataac cccaaataga aaagtttata ttaaccgtat cactattatc ggtaacaccc
   534541 gtactaaaga tgaggttatt cgtcgggaaa ttggcattta tgagggtagc ttatactcta
   534601 gtacagagct taatgaatct attaaaaaaa tcaaacgttt aggcttcttt tctgaagtaa
   534661 aaattcaagt ttcaaaactt aaagacattg aagataaaat taacctatat tttagcgttg
   534721 tagaaactca aactggtact ttttcaattg gattttcaca ttctaataac acaggtgcgt
   534781 cgcttaattt aggtgtacaa gaaagaaatt ttttaggtac aggaaataca ttaagccttt
   534841 ccttgtctaa ttctaaagca acaagagatg ttagttttta tttttctaac ccatatttca
   534901 ctcaaaataa acacagtatt agttatggca tattttctaa aaaattagac gcatctgagc
   534961 tagaattaga tgaatataag attgacgaaa atgggtttag tttaggctat agtgtaccaa
   535021 taacaaaagc aacaagaatt ggtgctaact taagagcttc aaagcgttat attacttgtg
   535081 gattgacctt ttctgacaat gatcacgaac caactcaatg tgctaaaaaa gacaaaactg
   535141 aactaaaatt aggcttaaat tggagcaaca acacacttaa tgactttaac tttccaacta
   535201 aaggtcaaca aagtaattta aattttagtt taactttacc tattgcagat tttcgttatt
   535261 ataagttaga tgcttctcat aaaagctact atccactaaa aaatgattta actttttctt
   535321 taagagggaa tctcggcttt gctcaaggtt atgatggtaa agagtttcct ttttttaaac
   535381 gctattatgg tggtggatct tcatcagtac gcgggtttga ctttaactct ttaggtgtaa
   535441 agtatttaaa tagtaataaa gctaagggtg gtgaactttc tttcctaact agtgcatcaa
   535501 ttattttacc aataaaactt attgacaata ataagaacat gcgtatcagt gtctttgttg
   535561 atttaggttc tgttagcgaa aaagcttcca attttgactt ggaagaatta cgtctttcaa
   535621 caggcattgc attctcttgg ttaacaccta ttggcccgtt agggttttat gctgctaggc
   535681 ctttaattaa aaaattaggt gataagacca aaacatttga ttttacatta ggtactagtt
   535741 tctaaaacct aaacataatt gtctttttag cttaatttta ataatgcata cactgggtga
   535801 tattgctaaa accattaacg ctaagcttgt gggtgattct aatgttgaaa ttacaggtgt
   535861 tgcttcaagt ttatatgcca atcaaacaca actaacttat attattaata gtaaatacaa
   535921 acaaacatta attcactcta aagctggtgt tgttattctt aataaagatt tattaagaat
   535981 ttgccctact aatgctctag tagttgacaa tgtttattta gcatttgcaa aagctacaca
   536041 tttgtttaaa aaacaaaatg tatgttatca gggtatccat ccaagtgcca aaattaacaa
   536101 tgcaaaaata gcaccaaact gtattattgg tagaaatgtt tctattggta atcactgcat
   536161 aattgcctca aatgttgtta ttgaagataa cgtcactatt ggcaattatg ctttaattca
   536221 accaaatgtg agtattttac aaggatgttc aattggtgat aatattgtta tatctcctgg
   536281 tgtagttatt ggttcagaag gatttggtaa tgctcaagac caacaaaaac actggcatag
   536341 tattgcgcac cttggttatg ttgttattgg taacaatgtg agtattggtg cgaatacaac
   536401 tattgatcga ggcacgattg aagatactca aattcacaat ggtgtacgaa ttgataactt
   536461 agtacatatt gcgcataatg ttattattga acaagattca gctattgctg ctacagtaac
   536521 tattggcggt agttgtaaac taggaaaaag atgtatggta ggtgggggtg caactattac
   536581 tagtcatgtt aatttagcag atgatattat catcacaggt gctagcactg ttgataaaaa
   536641 tttatctgaa caggggcatt atacaggttt tacctctatc agtaaacatc aaaaatggaa
   536701 gaaaatacaa gtatggctat taaatcttga taaaatcgtt cattatttaa atattaaact
   536761 taagaaatta aaggaaaaat agcatggaaa tgaatattca agatgtcaaa aactatctac
   536821 cccatcgtta tcctttttta cttattgata gagttctgga gctggaagtt ggcaaatcaa
   536881 tcgtagcatt aaaaaatgtt acctttaatg agcctcaatt tattggacac ttcccagatc
   536941 agccaattat gcctggtgtt atgattgttg aggctttagc gcaagctaca ggtattctag
   537001 cttttaaagc tgaagttagc aagccgacta atgggcagat atatatgctt gtcggtattg
   537061 ataaggttag atttaaacgc atggttgaac ctggagatca attacgttta gaggtaggaa
   537121 ttgtaacagt taaacggggt atttggaagt ttaaatgcaa agcaactgta gatagccaaa
   537181 ctattacaag tgctgagctt atgtgtactc aaaaagcaac agattaattg aaatttcttt
   537241 aaggagcgta agatgacgat agattccagt gcaatcgttg atcccagtgc aaaaattcat
   537301 aaaaatgctg aaatatatgc ttatgtcatt attggtgcta atgtagaaat tgactctggc
   537361 acaattgttg aggcgcatac cgttattcaa ggtccaacca ggattggaaa aaataaccat
   537421 atttattctt ttgcctcaat aggcggagat ccacaagata ttacttatgc agagggtcaa
   537481 gaatctagtt taattattgg gaatgataat cttattcgtg agttttgtac cattaaccgt
   537541 ggtacagaaa aagaaaactc tatcactcga gtgggttcta acaatatgtt gatggcttat
   537601 gttcatattg cacatgattg ccaggtaggt aatcatatta ttatgtctaa taatgcctct
   537661 cttgcaggtc atgttagaat ctatgattgg gcgattttag gtggttttac tctagctaaa
   537721 caattctgta tgatcggtat gcatacttat gttggtatgg gatgtcaaat taacaaagac
   537781 attcctgctt atatggtcgc ctccggcgtg caaaccagag ttagaagtat taattctgaa
   537841 ggtatgagac gaagaggctt tagtcctaat gcaattgctg ccattaaacg tgcttttaaa
   537901 gcagtttatc gtgaatctgg attattagat caatccctta aagaattaga acaatcagaa
   537961 tctgaccatc cagaagtggt gcaatttgtt aactgtattc gtagttctaa agttggtatt
   538021 atgcgtggac caactgagga gtaatactct aagagtgttc tttggataag tcttttttaa
   538081 agtctagtgg cattatcatt gctatgactt ttctttcacg aatactaggt ttagtacgtg
   538141 attattttat tgctcgatac tttggtgcta gtggtttaac tgatgctttt tgggtagctt
   538201 ttagaattcc taattttctt agacgtttat ttggcgaggg cgctctttca caagctttta
   538261 tgcctatttt agctgatgct aaagccaata atacacagat tgaagttcag aatattatta
   538321 atcatattgc taccaaatta ctttttgtgt taattgcaat cacactcatt acagttatta
   538381 tttctcctat tattattttt atgtttgcct ggggatttta tttttctcct gatctaatac
   538441 aatttaatct agcgtcagat atgttaagaa ttacatttcc ttatttacta ttcatctctt
   538501 taacagctct ttctggtgct attttaaaca tttataatca ttttgcagta cctgcattta
   538561 caccagtttt actcaatatt tctataattt taagttccat atatttatct aaacatctaa
   538621 atacccctat tatggcatta gcatggggag tattttttgg tggtgttgca caacttttat
   538681 ttcaaatacc ttttttaatt aaaataaaaa aactacctaa attagtactt ggtaatcatc
   538741 aagcagtcga aactttaaaa aaacatatgt taccagctct atttagcgtt tcagtatcgc
   538801 aaattaattt attagttgat actatgattg cctcactttt agttagtggt agtatctcgt
   538861 ggctatatta ttcagataga ctattagagt tacccctagc acttattggt attactttgg
   538921 caactgtctc tttggcaaaa ctaagtcatc attttactga taagaaccat gaaaaatttc
   538981 tacaaacaat tgacaatgcc ttaacaattg gattgttact tgggctacca gcctgtgttg
   539041 gtttaatatt acttgctaaa cctttaatta tcactttatt tcaatatgat caatttgacg
   539101 catttgctgc attacagtca tcgcttagtt taatggccta tggttcagga ttaatggctt
   539161 ttatttttgt taaagtttta gctcctattt ttttatccat aggagacact aaaacaccag
   539221 ttaaggccgg tattattgct atggtttcta atattttctt aaacattatt ttaggttttt
   539281 actttgccca tgtaggtttg gcaatagcta cttccatttc tgctttaatc aatgctagtt
   539341 tgctatattt ttatctgaac aaacaatcta tcttcaatat ttctaagaac ttatatcaaa
   539401 ctttctttaa agccttagtt tcaagcttta taatggctat ctttattctg atttttaaat
   539461 cagaagctga actctattta agagctagtg ttaattcaag aataatatta ttaggaacaa
   539521 ctattgtact ttcaagcatt atatattttt ccagcttaaa attgttaaac ataggagtac
   539581 aaaaataatg aatattgtaa aatgtattaa attaaaccaa aagcttgaag ctttagatag
   539641 agcgccctac cctggagaat taggtaaaaa aatattgaat aatatatcta aacaaggatg
   539701 gaaactttgg cttgaacatc aaactatgtt aatcaatgaa aataatttaa atttaatgga
   539761 ttcaaacgca cagaattacc ttaaagaaca aatggaaaaa tttttcttct caaaagaagg
   539821 tgcagataaa ataaaaggtt atagtccaga tgaataatgg agtactattc attatttctg
   539881 ctccttcagg atgtggaaag acttcattag ttaaagctct cattaaaaaa gttgagaatt
   539941 tatgtgtttc aatttcacat actactagac aaccccgttc aggtgaaata caaggtaaaa
   540001 actatttttt tgtttctaaa gacgagttta ataaaatgaa aagtagtaac aattttattg
   540061 aatctaccca agtatttgat aataattatg gcagctctaa acaatcagtt caagatttat
   540121 taaatagtgg atttgatgtt attttagaga ttgattggcg aggttttagg cagattaaac
   540181 aaacttttag tcattcagtc ggaatcttta ttctcccgcc ttctaaagtg gcattagaag
   540241 aacgtttaac taacagagga caagataata aaggcatcat taatagaaga atgcatgatg
   540301 cagtaagtga gatgcaacac tttaatgaat ttaactattt ggttattaat gataactttg
   540361 atgtagctct aaataattta tcaaccatcg tacacgccga acgcctgacg ttagcacaac
   540421 aatcaaacaa ataccaaaat ttacttaaaa cattaattta acctagaata ccaaacctta
   540481 ctaatattta ttagtagtta tctaattaaa atgaatcaag aatttgcatt atcatctact
   540541 caaaaaactt caagtttaga ggttcaaaaa tacccaccta ttttaagcag tgaggaagaa
   540601 catgaattag cagttcaatt atatgaaaac cataatttaa gtgcagctag aaaattagta
   540661 ttatcacata tgcgttttgt agcttttatt gctcatagtt ataaaggtta tggccttgaa
   540721 caagctgatc ttgtacagga aggtactatt ggattaatga aggcggttaa acgttttaat
   540781 ccacatagaa atgtacgtct tgcctcattc gcagtgtatt ggattcgcgc tgaaattcat
   540841 gaatttattt tcaaaaattg gaaaatagtt aaagttgcta caacgaaagc acagcgtaaa
   540901 ctatttttta aacttaaaca agctaaagca catatttaca attcattaaa cgaagaacaa
   540961 gcagataaaa ttgccaaaga tttgggcgta cgtcgtaaag atgtcttaga aatggaatca
   541021 cgcttacaat ttagcgatgt cacatttgaa gtgtttgatg aggaggattc tcatgcacca
   541081 gaacaatatt taaccaatga aaatatccaa acacctgaac aattgttgtt aacagacgat
   541141 tcaaaaaaaa cccaacaaca acgactttat aaggctttat catcgctaga tgaaagaagt
   541201 ttggatattt tacaatccag atacttgaaa gaagaaaaaa caaccctata tactttagca
   541261 gacaagtata gcatttcaaa agaaagagtg cgtcaacttg agactaaagc catgcaaaag
   541321 cttaaatcaa acttacaaga gtaaactctt tgaaagataa atttaaactt atgcatcaag
   541381 cttaaataat tttattaact aggagaaaaa atgaatattc gcccccttca cgaccgtgtg
   541441 gtcgttcgta gagtagaaga aaagaaaacc acttccagtg gtttaattat tcctgattca
   541501 gcaactgaaa agccttcaga aggtgttgtt gttgcagtag gtaatggtaa aaaaaatgac
   541561 aatggcgata ccattgcatt agacgtaaca atcggcaata aagtattgtt tgctcaatat
   541621 gctggtactg aaattaaagt agatggtaaa aaactactga taatgaaaga aggcgatatt
   541681 gtcgcagtta ttaaataaag gagattaaga atgtcagcaa aagatataaa atttggccca
   541741 gaagctagga atttaatgtt agacggggta aatatgttag ctaacgcagt caaagtaaca
   541801 ttagggccta aaggtagaaa tgtcgtatta gataaatcat ttggcgggcc tacgatcact
   541861 aaagatggtg tttccgttgc tcaagaaatt accttagaag gtaagttcga aaatatgggc
   541921 gcacaaatgg taaaagaagt ggcatcaaaa accaatgata ttgctggtga tggcacaaca
   541981 acagcaactg tgcttgcaca agctcttgtt actgaaggtg ttaagtcagt agcagcaggt
   542041 atgaatccta tggaccttaa acgaggtatt gataaagcaa cagaagttgc tgttaacgca
   542101 ctacacgact tctcacaacc ttgtaatgat acaaaagcta ttgctcaagt aggtactatt
   542161 tctgcaaact ctgacgtttc tgtaggtgat attattgccg atgctatgga aaaagtaggt
   542221 caagcaggcg ttattaccgt tgaagaaggt tctggttttg agaatgaact tgatgtggtt
   542281 gaaggtatgc aatttgatcg tggttatttg tccccctact ttgttaacaa tcaagataca
   542341 atgactgctg atcttgagtc tccttttgta ttgttacatg atgcaaagat ttcaaatatt
   542401 cgtgatttat taccagcatt agaaatcgta caaaaatcaa gtaaagcttt attaattatt
   542461 gctgaagata ttgatggtga agcactagcc actctagttg ttaacaatat gcgcggtatt
   542521 gttaaagtcg ccgcagttaa ggctcctggt tttggggatc gccgtaaagc aattttagaa
   542581 gacattgcta tactcacagg tagtgtagtt atttcagaag aagtagggtt gtctttagaa
   542641 aaagtaactg aagagcatct tggtactgct aaacgcatcg aaattggtaa ggaaaatact
   542701 gtaattgttg atggggctgg taaaaaatct aatattgatg gtcgtgttaa ccaaattaaa
   542761 gcacaaatcg aaactacaac aagtgattat gataaagaga agttacttga acgcttagct
   542821 aaactttctg gtggtgttgc agtaattaaa gtaggtgctg ctactgaagt tgctatgaaa
   542881 gaaaagaaag atcatgttga tgacgcttta cacgccactc gcgctgctgt tgaagaaggt
   542941 gttgttcctg gtgggggtgt tgccttagta cgtactatta aagctttaga tggattaact
   543001 ggtgataatc atgatcaaaa tattggtatt gatattgcta aacgagctat ggaagcacca
   543061 ctacgccaaa tcgtaacaaa tggtgggggt gaagcctctg ttgttctcaa taatgtagct
   543121 gatggtaaag ataactatgg ctataatgca acaacagaag aatacggtga tatgctcaag
   543181 atgggtattt tagatccaac aaaagttgtg cgtgctgcat tacaacatgc tgctagtatt
   543241 tcaggcctta tgattacaac cgaggcaatg attactgaca tccctcaaga tgctacacct
   543301 actgcttctc ctgatatggg tggtatgggt ggtatgggtg gtggtatgat gtaaatcaac
   543361 attgctctat tataaaaaaa gccccatctt tatggggctt tttttataat agagcaatct
   543421 cccaatggag agtaacatag tttaataatt taaattatta aactatctaa aagattttaa
   543481 aggggaatca atgcaacata aattaattat tttaataata tcttttttgg gattacaagt
   543541 acaagcaaat ttacaatctt tcgtaaattc aaaaactaat atcataatac ctcctactaa
   543601 aatcgacaat atttcacatt caaatattga taatttatct tcaaaagaat gtagtgtatg
   543661 tcattatgat atttataaac aatggacaaa ttcaatgcat gctaaaagca cagcattaaa
   543721 agaccctatt catggtcttt tttatggcgt ggttgtaggt aatcctaaag ttgagggtat
   543781 taaaacagga aaggataaag ataaatatcc agtttgtcta gaatgtcact ctcctgcagc
   543841 agcaaaagaa aaaaaaacaa aacttaatgc taaaaactcc ttctctgaag gagttaactg
   543901 tatcgcttgc cattctttaa ctaaatacaa aagaataaag aaaaaaaatg atagagtaaa
   543961 actaggcata aaagcttata aatactcatc ccatcaaata caaggtccta atggtactaa
   544021 taaaaaacat aaaagatttg gtgaaggtgg ggttgcaaat aatccaggct tatttaaaac
   544081 ctctaaggca tgcctaggtt gtcataatca acgtaacaat tctaaagaag taccactctg
   544141 tcaaactggt ggagaaatta tatctgcagg gggttctact acttgtcagt cttgtcatat
   544201 gccagtaatt gaaggtatta gcaatcacac aatgataggt ggacattctg ttgaaatggt
   544261 aagtaaaggc ctggtcatga caatcaaaac taaaaaggtt tctgatatgt tgtatattag
   544321 cgtcaatgca actaacttat tgcctcataa tttcccaaca ggagcaccat ttagaaattt
   544381 ttatattact gttactgcgc aagattacaa tgataatatt ttgtggcaaa gttcaaagac
   544441 tcatcctatg atagatgata aaaaagctat gtttatgtac ataattggtg atgacaataa
   544501 caaaccaaca tcaccaccta aagcaaccaa aattttagga gatactcgtt taaaaccaaa
   544561 tgaaactcgc atattaaatt ataagattcc atcaaatgat gtttccatag ttacggcaaa
   544621 agcttattat gatttgttat tagtaccaat gaaaaataaa tttagctcaa aattacctaa
   544681 gcgtttatta gagtctaaag aaatagcaaa agctatcgta gttattaggt agtttttgtt
   544741 aaaaaataaa aaatcctcgt cttttcgagg attttttggt atgatacttg ataaattctc
   544801 atattcaaac atatgaatag ctacgactct tcctctattg aagttttaac aggtcttgaa
   544861 ccagtacgta aacatccagg catgtacacc gaaactgaat gtccaaatca ccttgctcaa
   544921 gaagttattg ataatagtgt tgatgaggca attgcaggat ttgcttcaaa aattaacgtt
   544981 gttttatata aaaataattc attatctgtt gaagatgatg gtcgaggtat gcctgtagat
   545041 attcacccta aagaaggtaa atcaggtgtt gaggtgatcc taacaaaact tcatgcaggt
   545101 ggaaaatttt caaatgactt ataccaattt tcaggaggac tacatggggt aggtatttca
   545161 gtggttaacg ccctatctac cttagtagaa atttggatca aaagagatgc taaagagcat
   545221 cacataacat tctcaaatgg atctaagaaa acagaactta aagtaactcg taaggtaagt
   545281 aaatataaca caggtactat cgttaaattt aaacctgatg cgcgattttt tgacaatatt
   545341 aaattctcag caactaaact acataataat ctacgttcta aagcagtttt atgcccagat
   545401 ttagagatta atttttataa tgaaataaac gaaaaaacag ataaatggat ttacaaggaa
   545461 ggcttaaaag attatctatc caaatcttta gatggtttag attgtctacc aacagatcct
   545521 tttgttgtta attataaaac taacgaacaa caacttaatt gttcagttac atggacacag
   545581 tataacacta atattatagc tgaaagctac gttaatctta tcccaacaat tagcggtaca
   545641 catgttaatg gattaaggtc aggacttacc gaagctttaa aagaattttg cgagtttaga
   545701 aatttaatcc cgaaaaatat taaactcact cctgatgacg tttggcaaaa aatttcttat
   545761 gtgttatcca ttaagataat ggatccacaa ttttctggac aaactaaaaa aagactttct
   545821 tctagagaat gtgctagttt tgttgcaaat atagttaaag acacttttag tatttggtta
   545881 aatcaacata ctagcatggc aaaagaaatt gctcaactag ctattatcaa tgcgcaaata
   545941 aaacttaaaa ctaacaaaaa agttattcgt aaaaaaatat ttagcggtcc tatcctacct
   546001 ggaaaattat cagactgtat cagcactgac ctcaatcaaa cagaagtatt tctagttgaa
   546061 ggtgattctg caggtggttc tgctaagcaa gcaagaaata aagagtacca agctatttta
   546121 cccctacggg gtaaaatttt aaatacttgg gaaattaatt ctgaacaaat acttgctaat
   546181 aaagagattc atgacattag cattgcaatt ggtcttgaac ctaatagtga agatttatct
   546241 aatttaagat atggtaaaat ttgtattctt gccgatgcag attcagatgg tgcacatatc
   546301 gctacattaa tttgtacttt gtttatgaaa cattttccaa aacttgttca agagggtcat
   546361 atttttgttg caatgccccc tttatatcgt atagatgcag gaaaacaagt ttactatgcc
   546421 cttaataata atgaacgaga caccattatt agaaaggtaa aaaacgaaaa taaacgtgtt
   546481 aaaattcaag ttcaacggtt taaggggttg ggtgaaatga acccttctca attaagagaa
   546541 actaccatgc tatccaatac tagacattta atccaactta catcaaataa cccattacaa
   546601 atttttaaaa ccatggatat gttgttaagt aaaaaacgcg cagctgatcg aaaaaagtgg
   546661 ttagaagaaa atggaaattt agataatgct taatgctaaa cataaaatca aagcggttat
   546721 tcttttatct ggtggattag attctactac tactttagcc attgctaaat caaaaaaatt
   546781 tgaatgctat agtctaagtt ttgattatgg tcaaaaacaa gaatcagagt tacaatccgc
   546841 taaaaatatc gctaaaattt ttatcacctc tgaacacaga gtagtaaaaa tatcattatc
   546901 tggtattagt aaatctgctc taactaatga taacattgac gtaccaaaat tctctcaaag
   546961 caataaaatc ccaattactt atgtacctgc tcgcaatact atttttctat cttatgcact
   547021 agcatggtca gaagtattaa attgtcaaca tatatttatt ggggttaatg aactagatta
   547081 ctcaggttat cctgattgta gaaaatctta tattaaagca ttcgaaataa tggctaatct
   547141 tgctaccaaa caaggtattg aaggacaaaa attaaccatt cacaccccac taattcattt
   547201 gaataaagca caaattatca aaaaaggact ttctttaggt attgattaca cgcttacaac
   547261 aacgtgttat caagcagata aaaatggaaa agcctgtggc atttgtgatg cttgcgaata
   547321 taggaagtta ggctttaaag aggcaaaagt gccagatcaa actcgatatc aaacctagca
   547381 ttatttgtac agaatattct aataaaaaat tttgtaattt agtcttatat acttcttttt
   547441 tgacgataaa ataataattt tttgtaaata gttaaggaaa tgacaaatga gtattgaaca
   547501 aagagtaaaa aaagttgtag ctgaacaatt ggatgtaagc ggtgatgttg ataacaacgc
   547561 ctcttttgtt gatgatttag gcgcagattc tttagatact gttgaattag tcatgtctct
   547621 tgaagatgaa tttgaatgtg aaattcctga tgatcaagca gaaaacatta ctaacgttca
   547681 acaagcaatt gattacgtta gtaatttgta attctattta tcaacttaac aaataaggcg
   547741 cttatttctt tgaaataagc gccttattat attttccaac aaaaataata tgagtaaaag
   547801 aagggttgtt attacaggta tgggtataat ttgcccagtt ggtttaagtg ttagcgagtc
   547861 ttgggataat attcttaaag gctactctgg tattgcttca cttactaaca ttaataccaa
   547921 aggtcaatca gttacctttg gtggctcagt taaaaatttt gaagtaactg attatctaag
   547981 acctaaagat gctaaaaaaa tggacacctt tattcactat ggtatggctg ctagcattca
   548041 agctattgaa gacagtggta ttgaagttac tgagaaaaat gcttgtcgta ttggggttgc
   548101 cattggagct ggtattggcg ggctaggtac aattgaaaga accgcagatt tatttagaga
   548161 aaaaggtgca ggacgtattt cacctttttt tgttccttct tctattatca atatgatttc
   548221 tggcaatctt tctattaaat acggcttaaa aggacctaat tttgccatta ctactgcttg
   548281 tactacaggt actcataata ttggtaatgc ttctcgttta attgaatata acgatgctga
   548341 tgtgatgatt gctggtggtg ctgaaatgtc aaccaccaat tgtgggttag gtgggtttgc
   548401 tgcagcacgt gcattatcta ctcgcaatga tgacccaata agcgcttctc gtccctggga
   548461 taaagataga gatggttttg tacttggtga tggtgcaggt attatagtat tggaagagtt
   548521 tgaacacgcg aaggctcgtg gtgcaaaaat ctatgcacaa gtatcaggtt atggtatgag
   548581 tggagatgct tatcatataa cattaccttc aaaagggggc gaaggtgcgg ctagatgcat
   548641 gcaaaatgct atgaataact caggtattaa tgttgatgag attaattata ttaacgcaca
   548701 tggaacttcc acattagtag gtgatcaagc agaaacagat gctgttaaat tagcctttag
   548761 agaacagcac gcttataata ttgtaataag ctcaactaaa tcaatgactg gacacttatt
   548821 aggtgcttct ggtggtattg aagctatctt taccacactc gcaattcaag atcaagtggt
   548881 accaccaacc attaatatta tcaatcaaga tccaaattgt gatttagatt attgcgctaa
   548941 tgaagcaaga gaaatgacaa ttaaccatgc tatttctaat tcattcggat ttggtggcac
   549001 taatggttca attgtattga gcagaattta atatctttta tacaaacctt catacaaagc
   549061 agaaatctaa aactacctaa agtattgatc attttatggt tgagtcaaca attttaattt
   549121 tattagcatc agatattaat gcttcaataa attcataaat tgcaattgca ccattctgta
   549181 cactactaag tgcaacccct ttattcataa ccaaagacca gctttcttca gttgcaacaa
   549241 actttatagc accaccaatc aatgccaaaa taataataat actgagaata aatttaatca
   549301 tgtctctcct tagttgaatg aataatacca tttgctttta ataaagcatt aactgagggg
   549361 ttctcacccc taaactttat atattgttgc ataaaatcta gactacctcc tatttccaaa
   549421 atattataca agaaatctct agaagcatca gagccaatac cacctttctt ttgcacataa
   549481 taataagcat cagccgccaa aacttctgcc catttataac taaaatatcc tgctgcatag
   549541 ccaccactga aaatatgttc aaaagtattt aaaaaacgat tttcatttat cattggcatt
   549601 agagaagttt ttctttgaac ttgttttaat attgtgtaac tatctctagt agacatgtgt
   549661 gttttaagat cccacaatgc aaactcacac tgtcgtaaca tactcaatgc tgaattaaag
   549721 tttttagaag caataagctt gttatacaat tcatcaggta aaggcttcct agttttataa
   549781 tgacttgaga taagagaaat cacttgtttt tcaaacacat aaaattccat atactgacta
   549841 ggtaattcaa caccatccca cggcacacca gatatcccac tagcacaagg gtatttaact
   549901 ttggttaaca agtgatgtaa cacatgccca aattcatgga atagagtaac aatctcatca
   549961 aattcaaata aagctggctt atctttagta ggagagttaa agttacaaac cacaaaagca
   550021 actggttttt gattattaat taaaggttga taatctgtca tccacgcacc agaacgtttg
   550081 ttttctctag catataaatc aagataaatt ctaccaataa ctccactttc attattaaca
   550141 tctaaaactt taacatcagt atggtagcta ttttgttgta tttgcttaat cttaatttga
   550201 tacaaatttt caatagttaa gaataatcct tttaatacgc tattctctgg aaagtatggt
   550261 gttaaatcag atttcttgaa tccaaatttt tgttctttaa gtttttcact ataaaattct
   550321 aaatcccaag gctttaaatc aatacctgaa aaaatcttta attcttccaa ttctaattgt
   550381 gcttgagatt tggaatattc taccaagtca gataaaaact gaactacttc atcgacagta
   550441 ttaaccattt tagatgtaat cgataattgt gcataatgct caaaacctaa aatattagcc
   550501 atttcagaac gtaataataa aatctcatcc ataattggct tattattata attagttgca
   550561 gtaataccca aatctgatgc ccttgatatg taggctatat agacctcttc tcttaagtct
   550621 ctattatcta aataagtcat aacatccata taaacaggag tttgtaagct taactcataa
   550681 tccttatcga ttttaatttt taccagttca ttatcactat aaccttttaa ctcatgttta
   550741 ctaacaattt ttttccactc attggtagac tttaaaatat ttttagaaaa ttcattacta
   550801 agtagactaa gtttttcttt gatgacttta aacctatctg catttttacc ttctaaaccc
   550861 acacctgaaa gttcaaaacc ttttatgaca tctttaacaa tatgttgctg ttgtttgtta
   550921 agatttaccc ctctaagtga gttgtaagct tgatataagt ctttgttagt agacacatca
   550981 gaataaaaat tagtaataat tggtagtgtt tcttcatatt tttgattaaa ttcatcacta
   551041 aacatcactg catttaaatg cgaattaaca ctgatgtgct tttccagctc aaatttcatt
   551101 tggtcaatag gcataactac actctcccaa ttggtaccaa agcttgcttt ctttactatc
   551161 ttaagtccat ttctagttag tctttcaata gttttaacaa tatttttagg ttgaaagttt
   551221 ggtttcatag tatactaata tggtggaagg agtgggattc gaacccacga taccaaaagg
   551281 tataacacac tttccaagca tgctcattaa tcctctctga catccttcca aaattatatt
   551341 aatcaataat ttctgcaaat atatttcgca tttcttcttt tctaatatct agtattagat
   551401 gcaataattt atgagtatca tctacatttt taactctgat aattttagta atccgtaaat
   551461 caatctaaat catatcaata tttttaagct tatcctgtat aacaacttgt atatctttat
   551521 tttgaagctt caataattcg ctcaatttga tcatcttcaa tgcgtaacat taggggttta
   551581 aatgtattaa tttgatgctt gattaaaggg tattttaaat cctgccaatg aagttcatct
   551641 atgtttaaaa atttttcaac ctgttttgcc ataataggta atactggctt aagataagtc
   551701 atcaatactc taaacaaatt aatggctagc gaagttacgt catgcacttg tgtttgttga
   551761 tttggttttt ttatcaactg ccaaggctta tgcttatcga tatattgatt ggctttattg
   551821 gctaatttta taataacacg catagcttgg ttataattac gtgcttcgta gtgtttagca
   551881 atgatatccc cacaatcaaa aaattcttga taaaacttag attcaatagt ataagaagat
   551941 aatgttttgt tgaatttctt aacaataaat cctgcactac gtgaggcaat attaactacc
   552001 ttaccaacta aatctgaatt aatacgttgc ttaaaatcga tcaaattgag atctatatca
   552061 tcaattttag aagacagctt ataggcgtaa taataacgca aatattcagg gtttaaataa
   552121 ttaagataag ttctagcctg aataaacgta ccacgagatt tactcatttt ttgaccattt
   552181 atagttagaa acccatgtgc aaagattgca cttggtgtac gataattcga accaattaac
   552241 atggctggcc aaaaaagcgc atgaaaataa ataatatctt tgccaataaa atgataaagt
   552301 tctgtatttg agtctttgtt gaagtactca ttaaaatcaa tattttgttc atcgcataat
   552361 tttttaaaac ttgccatata accaattggt gcatctaacc aaacataaaa atatttacct
   552421 tctaccgcag gaatctgaaa accaaaatac ggcgcatcac gagaaatgtc ccattgttgc
   552481 aaaccttctt taaaccattc agatagttta ttactaattg catcttgcaa atgtcctgct
   552541 ttagtccatt ctttaagttg tacttcaaat tgaggcaagt caaagaaata atgttctgaa
   552601 tcttttgtaa ttggggttac gcctgaaata acagatttag catttttaag ttctattgac
   552661 gaataagttg cgccacaaac ctcacaatta tcaccatatt gttcattaga accacattta
   552721 ggacaatcac ctttaataaa acgatcagcc aaaaacattt gttttaaagg gtcaaaagct
   552781 tgtgaaatca cacgagtctt aataaatcca gcaacattta gcttgttata aatattagta
   552841 gaaatatctt tattttcctg actatgagtt gagtgatatt gactaaaatc aattgaaaat
   552901 gattgaaaat ctatctgatg tttattgctc atatttttaa ttaatacctc aggagtaata
   552961 tcaagctcat ctgccttaag cataatagct gtaccatgcg catcatctgc acaaacataa
   553021 tgacattcgt tacccatcat tttctgaaaa cgcacccaaa tatcagtttg aatatattct
   553081 agcaaatgtc ctagatgaat ttcaccatta gcataaggca gtgctgaggt aactagaatt
   553141 tttcgcgatg tcataataag atgattaata tcaagtgtgg cttatgtcat tatacgataa
   553201 aatatcgttc tatttcttaa tagaatacaa taaaaatggt aaatttaacg aacaaaaaga
   553261 ttaaaataat tctatccaag atagttgata tttatactga acaaaatatt atctcttcga
   553321 acaatattaa tattgatggt gataaagttc aaattaacat cgaacttaat taccctgcta
   553381 acagctatca tactacctta tctaatacta ttactgatgc attaacaaaa aatggtatta
   553441 acaatcatag tgttgatatt aaaaccaaga ttgttaagta tacaacccaa aaaggcgttg
   553501 atactttgcc agaggttaaa aatattattg ccattgcctc gggtaagggt ggtgtaggaa
   553561 aatcaactac tgcggtcaat ttagcgttag ccttacaagc agaaggtgct aaagttgcta
   553621 ttctagatgc tgatatttat ggtccttctc aacctagaat gctaggagta agtaagataa
   553681 aaccagaatc tagcactgaa ggtaaattat tacctatttt aggccatggt atacaaagta
   553741 tgtcaatcgg ttatttagtt aaggaagaca accctatgat ttggcgtggt ccaatgatta
   553801 ctcaagccct agaacaaatg ctaagagaca ctttatggcg tggtattgat tatatgatca
   553861 ttgatttacc gccaggaaca ggcgatacac aacttacttt atcacaaaaa ataccagtta
   553921 gtggttctat aattgtgaca accccccaag atattgcact aattgatgct aaaaaaggtt
   553981 taaaaatgtt tgaaaaagtt aacataccta ttttaggtat tgttgaaaat atgtctttac
   554041 atatttgttc taaatgtgga tacgaagaag ctattttcgg cacaggtggt ggtaaagcta
   554101 tggctattaa cgaaggtatt gaatttttag gctcacttcc cttaaaaatg gacattcaaa
   554161 cagacgttga cgaaggtaca ccaaccgtta ccaaagaccc agaaggaaaa atagctaaaa
   554221 tttataaaga aattgctaaa aaggtcagtg ccaaattaac ccaacaatct cgtgtaacca
   554281 atgccttccc aagtattacc atcgaataac actaaatagg caaatataga aagatttctt
   554341 agaataatac aataaagagg agagggtatt gtgtgctaat gttaattatt caaatttaac
   554401 tgattgataa aatcaattta atcttcatgc ttaaaatatt gactacttta gaatactaaa
   554461 agtaaggttt cttcaggttt ttttatatga taataggtgg ttaacactag gtaacaaaac
   554521 actataagtt tctgctatta ttgttaacat tatatattct tagtggtttt cggagacttg
   554581 gttgatggtg tattttggta tttcaattac caagtcagta ttacccataa ttgtttgaca
   554641 agataaacga gaatctggtt ctaaacccca agctttgtcc aataaatcat cttcaatttc
   554701 atctgactct tctactgaat caaacccctc acgcaggtaa acatgacaag ttgtgcaagc
   554761 gcttgacatt tcacaggcat gctcaatttc aacatcatca gcaagtagcg catcacaaat
   554821 actaacacct gattggatat taataataat tccttctgga cataattcat gatgaggtaa
   554881 tacaataatt tgaggcatat gagattccta aatatttttc ctaaaattca tcaatattac
   554941 gaccttgtat ggctttcata acagaactgt tcatacgcat ctcaacaaat tttaaacaac
   555001 tattctcaag attttcaata gcaattgaaa tagctttttc atcatcagaa tgaacaatat
   555061 cgaacaatgt atttctggca tttaagatat tattaagcat tttatcatca agcatattct
   555121 tgtctttttt aattgctgaa tctattgctt caatggttct gtttgcttct acttgtgttt
   555181 catgaagctt tctagtttga atgtcagttt tagcaaaaag aaaagaatct ttaagcattt
   555241 tttctttttg cacatcagtt agtccgtaag atggcttgat actaatattt gttttaacac
   555301 ctgatatttg ttcaactgca ctcacggata ataagccatc aacatctact tggaattcta
   555361 tacggatgcg agcatttcct gccaccattg ctggaatacc atataaatca aatttagcta
   555421 acgagcgaca atctctcact aactctcttt caccttgcag tacatgaata ctcatagctg
   555481 tctgcccatc tttaaaggtg gtaaattctt gtgcacgaat aataggaatt gtagtatttc
   555541 gatgaattat tttttccacc aatccaccca ttgtttcaag tccaagtgac aatggcaaaa
   555601 catctaataa caatatgtca ttttgtgatt taataccagc taaaatatta gcctgtattg
   555661 ctgcgccctt agcaacaact tcatccggat taatagaaca taaaactggt ttattaaata
   555721 aatcactcac catagagcaa actaatggta tacgtgtaga accacctacc ataataatat
   555781 ttttaatgtt tttaacatca acttgtgcat ctctaatagc ttgtttagtt aacaataaag
   555841 tgcgtttaat aagtacttta gctagagttt caaatttttt cttagtaata caataaggtc
   555901 ttttaataca gtcaaattct gaaaattcat aattacttaa agtttcttta gcaatacgtg
   555961 aaaattgctt aatttcttgc atttgagcag gtgtaagttc attaatactt aactgctcaa
   556021 tacaatcatt aataattagt tcgtcaaaat catctccgcc taaagtagca tcccccccta
   556081 ttgctaacac tttgaacacg cctttactaa aatttaaaat cgaaatatca aacgtgccac
   556141 cacctaaatc ataaatagca tgtacaccct cttcacctga ttccaaacca taagcaactg
   556201 ctgctgctgt tggttcatta agcaagcgta aagttttaag tccagccaaa gttgctgcat
   556261 ctttagttgc ttgacgttgt gcatcattga aataagctgg tgtagtaatt actgcaccag
   556321 ataacacgcc acctagtgaa ttttcagctc tttgtttaag tgaagataaa atactagcag
   556381 aaatttcaac tgcagataaa tttcccatag aggtgtgaaa taatacatta tttccatctt
   556441 taattaattg ataaggacaa tttttaaacg tactaacttc ttcatagctc atacccataa
   556501 aacgtttgat tgaaataata gtattagttg ggtcagtttt tgcataagga taagcatcac
   556561 aaccaaccgt taatttgtta tgcttaccac aatgtataat tgagggtaaa acagcttcgt
   556621 tattctcatc cataatgact ttactttgac catttatcac agatgcaact aatgaatttg
   556681 ttgtacctaa gtcaatacca atcactaatt tatgctgatg tggttttgac acttgactag
   556741 gttctgatat ttgtaataaa gtcattatta atattaatta ctatagccac tcattcatta
   556801 attgttttgc atgagtattt aaatgttcat agaattttaa ttctctaact aaatttttaa
   556861 tttcgttaaa tgtttttgtg ttggtaaata agagtctaat attatccaca ttatgtttaa
   556921 tatttaaatc atttttttca ataaaatcat atagtcttat ctcatcttta ctgattctaa
   556981 ttaactctaa attctctctt aattcaattt gattcattaa aaacttaaca tccatttgag
   557041 tgtatttttc atcaaatgca tcaataccat ttaattctaa taaataatta gcacgattaa
   557101 gtggagattt taaagtatca aatgctgtgt taattaatga tgtattttgc aatgctaaaa
   557161 ctctttcttt agcgctacta gtgataaatc tatcaggatg aaatttcacg atttgtttct
   557221 gatattcagc gttaagatta ataatactta tattaaaatc aggttttatt gaaaataatt
   557281 caaaatagtt ttccattttt ttaaacaact aaaccgtaaa agattcacca cagccacatt
   557341 cagctttagc atttggattg ttaaattcaa aaccttcatt taaacccttc ttaacgtaat
   557401 caacttgtgt gccatctaaa taaattaaac tctttgcatc aacaataatt ttaacaccat
   557461 tatcttcaaa tacagtgtca tcatcaaaag tataatcaac aaactccatg ttataaccaa
   557521 gaccagaaca gcctgtagtt tgtactctaa ggcgaatacc tatgccagaa ccacgattgg
   557581 ttagaaactc aacaattcgc tctaccgcat gttcagttaa agtaactgcc attattaatt
   557641 aaattttgct tttaatgtca ttaatagctg ctttaatagc atcttcagct aaaactgaac
   557701 agtgtatctt aacaggcggt agagataact cttctgcaat gtcagaattt ttaatttttg
   557761 ttgcttcatc taatgttttt cccttaaccc attgcgttaa taatgaactt gatgcaatag
   557821 cagaaccaca accataagtt ttaaatttag catcttcaat cacaccgtta tcatcaatct
   557881 taatttgcaa acgcatcaca tcaccacatg caggtgcacc taccatacct gtaccaacgt
   557941 ttttagcatt tttatctaaa acacctacat ttcgtggatt ttcataatga tccatcactt
   558001 ttttaccata tgccatctct tttccccttt tagtgcttat tgttattgta aacctctaat
   558061 cctatatatt tattacaatt attttaatgt gccgaccatt caactttact aatatcaaca
   558121 ccatctttga acatatccca aagtggtgat aaatcacgta atttatcaac tttagcacgt
   558181 actaaatcta tagctttatc aatttgtgct tcagtagtat aacgtccaat agtgaatcta
   558241 attgatgagt gggctaattc atcgtttaaa cccagagcac gtaaaacata cgaaggttca
   558301 agacttaaac tagtacaagc tgaacctgaa gatacagcaa tatcgttaat agccatcatt
   558361 aatgattctc cttcaacata attaaaactg atatttaggt taccgggaat acgactttcc
   558421 atatcgccat ttaccacaac ctcttccata tcaataaaac ctaccaataa acggtcacgt
   558481 aattgtctaa tttttgtatt ttcttctctc atttcagctt gtgcaatcgc aaaagcctcg
   558541 cccatgccaa caatttgatg tgtggctaaa gtgcctgaac gcatacctct ttcatgtcca
   558601 ccaccatgca tttgcgcctc aatccgtaca cgtggcttac gacgcacata aagagcaccc
   558661 atacctttag gcccataaat tttatgggct gaaaaactca ttaaatcaac ggataattct
   558721 gataaactaa tcgctacttt tcctgctgat tgtgccgcat caacatgaaa gaaaatatta
   558781 ttctgatggc aaagattacc aatagattca atatcttgaa tcacaccaat ttcgttatta
   558841 acatgcatga ttgataccaa tatagtatct tcacgcatag cgtctcttaa gatatttagg
   558901 tctaataaac catttgacat tggatctaaa tacgtcacct caaaaccttc acgctctaat
   558961 tgtcgacaag tatctaacac agacttatgt tcagttttta aagtgataat atgcttgcct
   559021 tttttatgat aaaaatgtgc aacaccttta atggctaggt tattagactc agttgcacca
   559081 gaagtccaaa caatttcttt tggatcagcg tctatcaaat tagccacctg ttgtctggct
   559141 tttttaacag cttcatcggc ttgccagcca taataatgag aatttgatgc agaattgcca
   559201 aaattaccat cctttgttaa aaattgtatc attttctgag caacacgttc atcaacaggg
   559261 gttgttgctg aataatccat ataagtaggt attgacatat ttatactcct ttgtttgaat
   559321 tatgatcgtc aattaccatt tgcaaggtct tgccgttcaa aaatgttcta atttgttcac
   559381 taacctcgca ccacaattga tgagaaatac attgacgtcc attgttacat actttaatgc
   559441 ctttacaacg acgtaaatca atattttcat ctactgcttc aataatttgg gttaaattaa
   559501 tatcacaagc tttagcatca agcaaataac caccacctgg tccgcgcaca cttttaacca
   559561 attcagcacg acgtaatttg gcaaataatt gttccaagta agacaatgaa atattttgtc
   559621 tttgtgaaat aatatctaga gtaataggtt ttccagtgtc attagatgcc aaatctaata
   559681 ttgcagttac tgcgtaacga cctttggttg ttaattgcat atcggtccta attctaataa
   559741 taacaataat tatacactta acctagttat ttagtcaagt aaagaacctt aacatcaaat
   559801 agttatttac tttcaatctc caaatcattc atagaagctc cttgctggtc tttaatgttc
   559861 aatttctttg aaatcttatg caattggaaa tccacatcgt gtaaatgtag caaaataaaa
   559921 ttaatagcct caacagtagg atcatcaaca ttattaccca cagcataaga atcaaaatga
   559981 tttgattgaa ttttattatt ttttaaaata cgaccaggaa caccaacaac tatctgagat
   560041 ttatcaatag atttaactac cacagaattt gaacctactc taacattatc ggcaagtaca
   560101 attggaccta gtatctttgc gccagctcca atcactacat tattacctaa gataggatgg
   560161 cgtttaccct tttgccaagt tgttccacca agcgtaacac catgatacaa agtacaatca
   560221 tcaccaattt cagcagtttc accaataact acacccatac catgatcaat aaaaaaacgt
   560281 cgaccaataa cagcaccggg atgaatttca atacctgtaa accatcttgc taatgatgat
   560341 acaaatcttg ctagccattt aaatttaaac ttccacaatc gatgactcaa acgataaaat
   560401 aacatagctt gcacgcctga atagcaagtt ataatttcaa agatatttct agcagcaggg
   560461 tcacgatcaa aaatactttg aatatcttca ataaatttca taggtcaaat tatatcatat
   560521 aagcccaata tgcctcaaat ttcgtttata tataaacaat tctattgtat taatacttaa
   560581 taactgattt aaaacgctta taattccaca agtattgctc tggttgagtt gtgactaaat
   560641 cttcaataac cttattcatt aacgatacat catctccaag tatgtttgtg tcagacagta
   560701 tttgtactgg tttaagatta agttcatagc ccttagcatt tggtagacgt tttgtccacg
   560761 ccataattac ttgagcatta ttctttctag taagtcttac tagtaaagtc atggtacgtg
   560821 tatcttgtga gaaaaatggt gctaagatac tacccatttc accaggatct tggtcaggta
   560881 atatagcaat aagttgtttc ttattaattg ctctttgcaa tttaataaca ccttttttat
   560941 tagctggtac cattaataaa tcaccctgct ctcgttttga aagtaataac ctgttttgtt
   561001 gtttattttt taaaatttta tacataaatg tgactggctt agttagtgat atcattctag
   561061 ctaccaactc ccaacaacca aaatgtggta ctaataagat aacagcttta ttacttctaa
   561121 gatgctgaat acctaaggtt tttgtaacgt atttgacatt atcatcaaaa ttcttaaacc
   561181 aaataaatcc agattcactt aaacctttgc ctgactctat tagagacttt ctaattagga
   561241 tttgttgttg ttttgaattt aaccctggaa aacaaagttg aatattttta cttactatag
   561301 ctctagagtt agactttgtt aaatacaaat attggccaat aaccgtacca ataaaatgat
   561361 ttaatttcag cggtataatt gaaaaaatcc aaagaataaa cctaatcatt ctaacctttc
   561421 ttggtttcat ccaacatagg tttcatggca cttagtagat ttttgtataa attaggtgta
   561481 cgtttttctt cagttaataa ccacttctta aaatgcatcc gctcagtagg catttggtaa
   561541 caagctggac aagaatcttt aatcacaggt aagtgtgtta ttttggcaaa atcagccaat
   561601 tgtctttctc gaacgtatgt tagtgggcga ataactcgta aatcctttgc atcattaata
   561661 taatgagctt tcatagtttg aattttgcca ttatgacaca ttgacatcat tagtgattca
   561721 gccaagtcat ccaaatgatg tcctaatgct aaaacattat aaccttcacg ccgtgccact
   561781 tggtacatta gtcctcgttt aatgcgagcg caaaaagagc aatatgaatt tcctttcatg
   561841 cttttttcag cttgcttcat aatcgaaaaa gtttcgaaaa aatacggcgt atcaaatttt
   561901 ctaaaaaaat attccaaagc ttgcggctca aaaccatcta ttttagggtc aatagtaacc
   561961 acaccaaatt caaaataaat tggggcagaa actaaaaaat gtcgaaaaat atggaacaaa
   562021 ctcaacgagt ctttaccgcc agatactgcc agaagcactt tatcgtcttt cttaatcatt
   562081 ttaaaatcat taatagcacg accgactaat ttaactagta attttggcag aactattcta
   562141 ggattaacca tatacctttt cttagaagaa tttattttat ttgtgaaaac cgttttcttt
   562201 gtcttgctat atttcctgta ttcgaattat tttcaatacc tgctatacaa aaaagtcttc
   562261 tcactattgg ttatgttaat ggatatttca gataataatc ttttttttat aactcctact
   562321 tagatcacct ttattaatag tataagacac tcatcaaatg aaataaaatc attataaaaa
   562381 atcaaaataa taaatatatg gggttactaa atcttttatt agataattaa tatttatgtt
   562441 atagtttcta actattgtaa ttttatattt aatacttttt acatcaaact ataattggat
   562501 aaaaactgtc ttttttaaag aatgataaat caaatcttga tagttataaa agataaaatt
   562561 catgttatct aattcagtca aaccatttag taacgcacta ataatttcat tatattttgg
   562621 gtttaattga tagattttat gtttaattaa aacgaaatct tactcaggtt acatcattgt
   562681 atagcctaat ttataatggt gataattgat caatgatttc tttaaaatta agcactaatt
   562741 cttgataatt tttaaacact tggatataat taagatttac actttgttca ttattttgcg
   562801 ctgcaataac aaaacttatc tgagagttag cattattata tcttcgtctt tcttcaatag
   562861 tccgagcttt ggcagttttt atttgcgctt tacttaattc aagtatttct actaaatatt
   562921 tgatcttttg ttttaataca ttcgctttag cataaatatt tagtaattgc tcttgctttt
   562981 tctctttagc tttagcaagc attatttgtg tttttgtaat gtttgattta gcttgaatat
   563041 taccgatagg atagctaaaa tctaagccaa tattccatga tgaacttgga ttaaaaatag
   563101 agtttgtata atagctattt ttactttcat ttgtaatgcc aagttttaag tcaaattttg
   563161 cttttgaatt actcttatca ctctttaatt gaagttctaa caaatcttga tttaaatcag
   563221 ctatttttaa tactctagaa ttagctaata agtactgttt aagatcatct ttattaatta
   563281 tgtaaggctt atataaatca aattcagctt taacgctata aagattaata tctaaaataa
   563341 tagataattc ataacgtaaa atatttaaat attgttgagt ttgaagttgc ctatgtttag
   563401 cgctatgata agcatcttct tgcaataaca catcaacttt gtcaataact gccatcttaa
   563461 atttttgttt aactaaagtt aattcttgag ctgctaaatc tagccgttga ttatcaatta
   563521 ttaaacgctc ttgtatgtaa gctaaatcaa taaatttttt taattggaca agaataaaag
   563581 cttctttttg ttcagcaata ttaagcttag atatttgcat gttaatacta gataaacccg
   563641 tatttagttt atcatttata ccacttgcat tctttaataa tggatgaaca taatcaatag
   563701 agaatttact attattagta tctacattag tagttgtatt cttattttgt tgtctccaac
   563761 tatgtttaaa agtaatatca gcgcctgaac ttactatttt tttagttgcc aaaaaatcaa
   563821 ctgaaatagt atttaaatta ttatctatat ctacattgtt aaaattagtt tttactccaa
   563881 caagccaatt ttgattagct gtagtttctt gttgatcaat tttcttaatt tgtaaagata
   563941 aatcaagctt tgtaaaaaaa ggatgtatat cttctaaacg ttcaataaat ttattttgtg
   564001 tcattgcttt agaattaaaa caaaaaataa aaataaaaat aaaaataaaa tgttttttca
   564061 tatcggaatg acttttataa tttcactaat aatagcgtat aattttttac ttgtagtatc
   564121 aattactaca tctgctactg tctgatataa aggcccccgt tttaataata aattattaaa
   564181 agttttttct ctgtcatatg attgttcaag tagaggtcta gatttagaat tcatggtata
   564241 cttaagtaat tgttcaactg ttgatgatag atatattaca aaattaccct gcttaaggat
   564301 ttttcgattt tgagggttaa taacgatacc cccaccagta gcaataacaa tatgcttaat
   564361 ttcacataaa tcagccaata tttgcatttc acgtttgcga aagcccttct ctccctctac
   564421 atcaaaaata tgattaatag aaacacctgt tcgtgctact atctcaaaat ctgaatcaaa
   564481 aaaatcacga ttaagaatac aggctaaacg acgaccaact gatgttttac cagagcccat
   564541 aggcccaact aaaataatat ttcttgacga attactactc acgaaaactt atgctgattc
   564601 gtaattgaaa caacgatacg aataagatac cttatcattt tttatcaatt tgaaaaaata
   564661 tcataagatt catattctaa ttttattcct ttagtttaga gcaatagaat tgctaaattt
   564721 tttgctttca caatactaaa aataacatgt tttttaaaaa atcgttcaca taatataatt
   564781 tcattagcaa aatcccttaa caatccaatg ttggtattgc tcatttctcc catagacaca
   564841 attaaaatat aaagtttgca attgttcggt tactggacca cgtgtaccta aaccaattat
   564901 acgattatcc aactcacgaa taggagttat ttctgctgcg gtacctgtaa aaaatgcttc
   564961 atctgaaata tacacctcat cacgagtaat gtgtttttca atcactttat aacctaaatc
   565021 agttgccaat ttgaatactg tatcacgggt aattcctgct agtgctgaag ttaaactagg
   565081 tgtgtaaata acactatctt gcacaataaa aatattttct ccactacctt cagccacgaa
   565141 accatcaacg tctaacaata atgcttcatc ataaccatca attaaagctt cctgtaaagc
   565201 aagcattgaa ttaatatagt taccattagc tttggcttta gtcatcgtaa tattaacatg
   565261 atgacgcgtg taactggaag tccgaacacg aataccattt ttcatattat cctcacctaa
   565321 atacgacccc cactcccaag cagcaataat agtatgtacc ttaagcccat cagcacgtaa
   565381 tcccatacct tctgaaccat aaaaacacat agggcgaata taagcactat caagattatt
   565441 tttagcaact gcgtcttttg agacttgatt aagtttgtct ttggaaaaac caatatccat
   565501 attcataatc ttagcagaat taaacaacct attaacatgt tcttcaaggc gaaaaattgc
   565561 tgctcctttt ttggtttcat atgcacgaat accttcaaac acacccatac cataatgcag
   565621 agtatgagtc aatacatgga ctttagcttc acgccaatct atccaataac catcaaacca
   565681 aattaagcca tctctgtcat caaatgtatg catttttatt ccttatccaa ttcaaataca
   565741 gcgtgtagtg aacgcactgc caactctaaa tatttttcat caattactac tgaaatctta
   565801 atttcactag tggaaatcat ctgaatatta ataccctcat tgtgcaatac ctcaaacatt
   565861 tgagtggcga taccagcatg agaacgtatg ccaataccaa ccaatgatac cttaactact
   565921 ttatcatcac tttgaacagc tattgcacct atctctttac atacattatt taaaatctta
   565981 ctcgcagtct taaagttatt tctatgtaca gtaaaagcaa aattagttaa accttcacgt
   566041 gcagatacgc tttgtacaat catatcaact tcaatattag cactactaat tggatttaaa
   566101 attttaaatg caataccagg ttcgtctagc acaccgatta aacttaattt tgcctcatct
   566161 ttattatgag caatacctga aataactacc tgttccacaa tattttcctc tctggtaatt
   566221 aatgtaccta agggattatc aatcaaagat gataatactc ttaatggtac tttatatttt
   566281 gatgcaaact ctactgaacg aatttgcaaa acttttgagc caagtgatgc catctccaac
   566341 atctcttcat aactaacaac atttattctt ctagcattta tctcaatacg tggatcagtt
   566401 gtaaaaacac catctacatc agtataaatt tgacattcat cagccttaag agcagtaaca
   566461 agtgccacag cagtggtatc agaaccacca cgccccaatg tagtaatatg tccattttca
   566521 tccactccct gaaatcctgc cacgacaaca accttacctt gatctaaact gtggaaaatg
   566581 cgatgattat caattgactt aatacgcgct ttaccatgct cagagtcagt cataatacat
   566641 acctgcggac ctgtgtaaga aactgcatca caacctaact gttgcaatgc catagtaagc
   566701 aaagcgattg tcacttgttc tccagttgtt agcagaacat ccatctctct taaagagggt
   566761 atatcttgaa tggtttgtgc aagcgcagtc attctactag tttcaccact catggcagat
   566821 acactaacca ctaattgatg gcctttctct ttaaatgctt taattttttg tgcaactgcc
   566881 tgaatacgct caaccgaagc gactgaagta ccgccatatt tttgtacaat taacgccatt
   566941 aattataatt caattaacca aaaaaatccc actaaaacaa gcttttttaa acagtattta
   567001 atacttaatt actgtttaat tattaaagat atattttgga ttgaaagcat aaatcagaaa
   567061 gtcagcgcaa tcactacatc aataattaat gcttcggaaa taaacatagc taatgcctaa
   567121 gcacctatta attgtaccat taatagcggt ataaaacttt ctattataat actaaaatta
   567181 aaaaataatg atagagtaat tatttagaac caaaaaaatg atcaaagttt aataagtcct
   567241 atcttatttt aaaaaacctt ttaaacgtta ttataatacc ccttattgtt tatcgatacc
   567301 tatttatcta ggtaaaataa taattttcgt ttttctaaaa aacatgacat ctgatttatt
   567361 tactttaatt tttctaatag ctatttttat ttatatgact atcttgttgt ggttgaacat
   567421 cagacaaaat aaagctatta ttcaatcatt tgacaaggta cctaacgaat ttagaaaaga
   567481 aattacacta aaagatcatc aaaaagcaac tgaatataca caagctaaac ttaaattaaa
   567541 tcattttgaa gttatatttt caaccactat attactacta tggacacttg gtggaggatt
   567601 agactattta gacaatattt ggcaagaaca aactgacaat atcttgtatg caggtgtagg
   567661 atttattgta agcttgataa tgctaggaag tttaatagat ttaccgttta gtgtatatag
   567721 aacttttata ttagaacaaa aatttgggtt taaccaaaca aatataaaaa cttttattac
   567781 ggatttactt aaaggtgcat tacttgtttt ggttattggt ttgccattaa tttatgctat
   567841 tctttattta atggatacta tgagtgagta ttggtggttt tatgtttggc tagttctcat
   567901 tgtattttct ctattgatat tttggcttta tcctacttat attgcgccga tttttaatca
   567961 atttaaaccc ttagataata ttgagttaaa aactaaaatt aataatttac ttgaacgtac
   568021 aggatttaga agtgatggta tatttgtgat gaatggttct aaaagatcat cacatgccaa
   568081 cgcctacttt acaggtattg gtaaaaataa acgtattgta ttttttgata cacttattaa
   568141 aaatatgagt gataatgagg ttcaagcaat tcttgctcat gaactgggac attgtcacca
   568201 ccgacatgtc attaagcaca tgattagttc atttatcacc tccttactgg gtttggcatt
   568261 acttagttat ttaattaatc aaaattggtt ttttcacggg cttggtatta gtcatccatc
   568321 aaaccatagc gctctgattt tatttacact aaccatacca gtgtttagtt ttcttattac
   568381 tcctattaat aattatctat cacgaaaata tgagtttgaa gctgacgtct ttgctactaa
   568441 acataccaat gcaaatgatt tagtatcttc actggtaaaa ttgtatcgag ataatgccat
   568501 aattctcgca ccagattata tgtattctta ttttcatgac tctcatccaa gtgcgttgat
   568561 tcgtattaat cagattaaga cttataagta ataatacgat atacttaaaa tcaactaaag
   568621 gagagaatta tcaatcagtt aatattaact ataatgttgg ttgcatcaag taacgcatta
   568681 tccaatgata aaggtaagga attacacaaa gaatcttgta tcacttgcca tattgttgaa
   568741 cacaataata ctttttatac aagaaataat tcacgtttac acaatcattt tgatttgcgt
   568801 aaacaagtga gtaattgtgt taatgcattt aacattaatt ggcttcctga tgaagaaaaa
   568861 tcagttgtaa atcacttaaa taatgaatat tatgatttta gaaagtagca taaaatatta
   568921 cctctaacat gcgcctaaaa atggcgactt aaaaaaattc aaacgcagca cagcactaaa
   568981 ataaatataa ccccagataa ttttaataaa gtacacatag gattggtcat tactcgttac
   569041 aaaaaacgat tattagttaa aataaaatca ggtgagttgt accaatgtgt taccaaaaac
   569101 aatattgatt tatcagttgc tggtgatagg gttatctttc agataaccca gtctaatcaa
   569161 ggtatcgtta ctgccatact tgaacgtcat aatcaacttt atcgtacaca taaactcatt
   569221 gctactaata tagaccaact atggttagtg gttgctatgg aaccacatta tcaatttgaa
   569281 ttgattgatc gttatttaat aatggctgaa aatgcaaaac tacctattaa tatagtggtt
   569341 aataaagttg agttaacaaa taatattaaa aaggttaaat atgatttttc tatgtataaa
   569401 aatattggtt attcaatcaa ttatttaagt gtcaaaaagc aaataaatat cgataaattc
   569461 aagcttaaac taaataataa gacccatatc tttttgggcc aatctggtgt agggaagtct
   569521 tcactaatta ataaattaat tccagaacta aatctacgcg ttaatgaaat atccacaaaa
   569581 agcaaacttg gtaagcatac aacaactaat actacgcttt accagattcc ttcaggtggt
   569641 gatttaattg attccccagg tattcgtaaa ttccaattag atgaattcag taatcaagaa
   569701 attttaaacg ggtttaaaga atttaatcca tttactaatg cttgtaaatt taggaattgt
   569761 gctcatatct ttgaaccaaa atgcgcaatt aaattagcag tcaaattagg cgatattcac
   569821 aagaaacgtt atcaatctta tataacacta gtttcatcat aaaacaagat taattattaa
   569881 taatactatt tgctaaaaat acattcataa attgtaatga ggtctctata taaaatatca
   569941 tctatttcat aatcaccaat aatagaataa gacatctata tatatggaaa aataactata
   570001 acgtattgga ttatatgtta aagctgccca ctataatatg gatgttgatt attattaaaa
   570061 tatacatcca ttaagaataa cttttaacat tagtataacc tatattttat aagttctctt
   570121 caaattaata aaaacgtagg tttttcaaca gtaaaaaata aatagcatgt ctttaaattt
   570181 aatataataa tccactggca actccaatgg taatattcac actttatacc ccactaacct
   570241 agattaatta tacctaattt agctaattaa ctagaagtcg cacgatctac cattctatta
   570301 aaagtatatt tgaactagta tcaagaataa tttttaattt atctgtgtta acatttcatc
   570361 atacacttat taactgatta taacattcgg ttactaatat caaagggaat gttaactaat
   570421 atagaaataa ccttataaga tctgaacaca ctaaaactat cttttcaata taagatatca
   570481 aaatagataa atattatttt attttggaga aattaaaagc aaatcttgct atacttaacc
   570541 agccaagaac caatagcata ccacctatcg gggtaataaa aaacaagcca tacaatttag
   570601 tcaaagtata taaatacaaa ctacctgaaa acataacaat acctgctata aaaagccaaa
   570661 tactttggtt aatagactta actataatac gttgtgattg tatagctaat attgcaatta
   570721 tcagagtatg atacatctga taggttattg ctgtttgtat acgcataata tcctctattg
   570781 gtaaaacata cttaaaaata tgtactgaca tcgcatccat cactattacc atagtaccac
   570841 ttaatgctat aaatatccaa aaaaaattca tcgattactt tccttattat acaaaatctt
   570901 acaaccatac acttaaatag gtaatcccaa tccggaaaca taacaaataa tgtagaatct
   570961 aggttaaaac taaaattaag cttaacaaca tttcacgaaa aaaaattatg ttttaatact
   571021 ggattgaaac ttttgataaa aattgataat gatgcatata ttaagagtta acttttaata
   571081 tatgattatt attttccttt aatacaaaca ataaatacat ttctctgctc atctttataa
   571141 ctacaatcag tctatgctat aattataaat caattcttta tatatggtgg ggcgtgaacg
   571201 atttgaacgc tcgaccagcg gattaaaagt ccgatgctct accaactgag ctaacgcccc
   571261 tatttattta acactctaaa ttttagaata cttcgcgtat aaatatagaa aaatgaaatt
   571321 atacattaat cgtactttat aaattaatca aaactaaatc ttattaatga tttctttaag
   571381 aaatttacct ggcttaaaaa atggtacaaa cttctcactt acctctgtcc tttcgctagt
   571441 tttaggatta ataccttgtc gagctttacg atatttcttg taaaaaccac caaaacctct
   571501 tatctcaacc ccctcaccag aaacaatacc ttgtgttaat tcttctaaaa ttacttcaac
   571561 cgctattttt gcatcagttt tagataagtt agaactgttt gataagttta agataagatc
   571621 gggctttttc ataataggta aaaaacaatc acaattcact attgttactt attatctttt
   571681 gcttctttta acaaatcacc taatgtagaa ccagatacta tatcagaaga ctgcttatta
   571741 taatcttcca ttgctgcttt ttcttccact gagttttttg ctttaatact aactaaaata
   571801 ttacgagttc ttctgtcaat attcaaaatt gcaacttcta tttcttcgcc agtttttaat
   571861 attaaagtcg catcttcaac acgatcttct gaaatttccc ctgcttttaa atagcctgta
   571921 atatcttcat tcaaacgaat aactgcacca cgtgaatcaa cttccataac catacctcga
   571981 acaattgatc cctttttatt agcagatgca tatcgcataa attcatcttc taaaagctgt
   572041 ttaataccta aagaaatacg ctctttttca gcatcaatat tcaaaataac cacctctaac
   572101 tcttgccctt tagaataact agataccaat tgatctgaag attgtttttc ccatgaaata
   572161 tcagctaaat gaattagacc gtcaatacca cctaaaagac caacaaataa accaaagtca
   572221 gtgattgact taaccctaac aggaatttta tcacccttat tatgtgttgc ttcaaatgat
   572281 tcccaagggt tttcttgagc ttgtttcata gataatgaaa tacggtgctt agattcttga
   572341 acatctaata caaccacttc aacttcttga cctaatttaa caattttaga aggacgagca
   572401 ttagcatttg tccaatccat ttcacttaca tggactaagc cttcaacacc ctcttcaata
   572461 ctcaaaaatg caccataatc tgttaaatta gaaaccgtgc cttgtacttt cttaccgata
   572521 ggtaaacgat ctgaaatact atcccaaggg ctaacagtta gttgtttaag acctaatgat
   572581 acacgcattt tctctttatc ataattaagc actttaacaa taattttatc gccaatagtt
   572641 aatttttcag atggatgatt aacacgctgc caagaaatat ctgtaatatg taacaaacca
   572701 tcaacacctc caagatcaac aaacgcacca taatctgcaa ggtttttaac aataccttca
   572761 atttctttac cttcttcaag ctcttcaagt agcgcctctc tatctgcaga attagcttct
   572821 tgcaatacag cttttctaga aatcacaata ttatttctaa cttcatccat cttaataaca
   572881 atagcttcaa tttcttgacc cgttagatat gagaaatctt ttactggacg tacatcaact
   572941 aacgatccag gtagaaatgc tttaactaca ccaatatcaa ccgtcaagcc ccctttaaca
   573001 gcaccagtta caataccagt tacaacttct ttagaattca ttgctaattc aagtgaatgc
   573061 catagcttaa tacgcttagc atcagcatgt gataacaaag tattacccag accatcatca
   573121 attgatttaa gtgcaacttc gacaatgtca ccttcttcaa ccttcaattc tccttgttga
   573181 tttttaaatt catctagggg aataaaaccc tctgatttga gtccaacatt aacaatcgct
   573241 ttttcacgat tgatactaac aacggtcccc actaagagtg caccaacttt tacgttttgt
   573301 tgttctgcac tattttcaaa cagttcggca aatgattctg acatattatt attttgatat
   573361 tgaccggtaa ttattaagct atttgcggta tagtatgtgc ttaatatatc atcgggttaa
   573421 tttatttaag aggcttaacc gcttaagcct caactaatgc tatcacttga atgataacct
   573481 catcaataga caatttagtg ctatcaataa tgagtgcatc tttggcaggt ttgagtggtg
   573541 agtatttacg agtataatca cgtttatccc tatccaccac atctgataag atgttcaaaa
   573601 ttataccctc actaccttgt gcttgcaatt gttttaagcg tctattaact cgctcatcaa
   573661 cacttgcagt taaatacact ttaaatagtg catcaggaaa aacagttgtt cccatatccc
   573721 taccatctgc caccagccct ggtgtttcgg aaaaatcctt ttggcgtttt aaaagcatag
   573781 cacgaaccac ctcaatagag gcaatttttg aagccatctt acctattttc tctgtacgta
   573841 aaatcttgga cacatcttta ccatcaagat aaatactcac aagcttattg cccgatttag
   573901 ttttaaattt tacatcaaga gtttctgcaa tctttctcaa agccttttca tcagcaatat
   573961 taatttctct agtatcaatt gtcaaagcaa aagcgcgata aattgcacca gaatctaaca
   574021 aatgccagtt ttttttttgt gccataattc ttgctatagt gccttttcca accccacttg
   574081 gaccatcaat agttaaaact ggtattatat tttgactcat ttacctataa tctataaatt
   574141 caaacgtctt aattttgtca ttaaccacat ttaattaatg tttactaagt ttttccttat
   574201 aaccctgcac aggtaaatat tctacccaac tcttttatca ttaatataat aagttaaaac
   574261 aaacccttgc taccataatt tttaaaatca tgttttcgtg aaatgattgc ataatttgct
   574321 agcatgacaa cggctataca agtcttaacc tgttttacta aacactaaca taatataaat
   574381 aattgacatc ttttcacttt acttcagcac gcatatgagg aaacaaaata acatcacgaa
   574441 ttgacggcga atcggtaaat agcattacca atctatcaat accaatgcct tctcctgctg
   574501 taggtggcat gccatactct aaagcacgaa tataatcagc atcataatac atagactcat
   574561 cattacctaa atctttctct tcaacttgtt ttttaaaacg ctcagcttga tcctgtgcat
   574621 cattaagctc agaaaagccg ttagcaattt cacacccact aataaataat tcaaaccgat
   574681 cagtaataaa cggattatcg tcatttcgac gtgctaatgg tgatacttca gttggatact
   574741 cagtgataaa agtaggctgt aataattttt cttcaacagt agtctcaaag atttcaattt
   574801 gaatcttgcc caaaccccaa ttttctttaa tttgaatacc taatttttct gcagtttgtt
   574861 tagcattttt ctgatttaaa tcagttgcta tcaagcttgg attatattgt aaaattgaat
   574921 caaccacact aatacgttta aatgacttaa aaaaatcaag attgttacct tgataataga
   574981 cattagcgct gccacataca tcaagtgcga tactgcgaaa taatttttct gtcaaattca
   575041 ttaaatcatg atatgttcca taagcctggt aaaattcaat catcgtaaat tctggattat
   575101 gtctagtgga aagtccttca tttctaaaat tacgattaat ttcgaatact ttattcatac
   575161 caccaataat taaacgtttt aagtaaagct caggtgaaat gcgaaaatac ataggcatgt
   575221 ctaatgcatt atgatacgtt tcaaatggtt tggctgttgc gccacctgga atagtttgta
   575281 acataggtgt ttctacctca ataaaatcat gatgattgaa aaaattgcgg atatagttaa
   575341 taatttgact acggcgttta aacgtatttc gtgatgtctt attcataatc aaatcaacat
   575401 aacgctgacg ataacgaatt tcttgatcag acaagccatg aaattttcca ggtaacggac
   575461 gtagtgattt agttaacaac ttaatatcgt caatacgaat tgacaattca cccatattgg
   575521 ttttgaataa aatacctata gcgccaataa tatcaccaat atcccatttt ttaaactgtt
   575581 cattataaaa actctcaggt agcttatcac aagtgacaaa aagctgaatt ttcccactag
   575641 aatcttgtac atgtacaaaa ctaaccttac ccataacacg cttgagcatc atccgtcctg
   575701 ctattgatac ttgcatattc tttttctcta gttcttcttt agaaaaacct ttaaattctt
   575761 gaataatatt ttgtgctaag ttttcaggct taaaattatt aataaatgga tttccaactt
   575821 ctcttaataa ggccaatttt gattttcttt taagaattaa tttattgtta tcttcgtctc
   575881 tcactggact ccttaatgtg ttttgtattc tagctctgat ttataccaat accttttctt
   575941 tagccaaatt ttatttaaat ggttctaaac gttacaattg aactaataaa atatcacgat
   576001 tataatagcc ttgataagaa tcaagtgtcc aattacgtac caaagttaaa tcttttaaag
   576061 ataattaata tttattgatt ttcatacaaa tactaacaaa ttataaatag tggaaataca
   576121 ctaactctaa atgataacaa cttgtatata agcgttatta tgtctttagt tatttaatta
   576181 atttgatcat aacaattgcc taaattatta taaatatcac tatcaatatt attcaacgtc
   576241 aaagtctatt caaaatattg attctatagg ataaaaacca gataatacac ccttgaacta
   576301 tttaaattat ttgtaatagt actcaatata cttcctatcg acaaaccatt attaccttgt
   576361 aattgatata aatcaaccaa aatctaatgt attctcaaca aacacatgat ataatcaaat
   576421 tgatgaactt tattataaat taatgcaaaa acaatttttt gtgtaacctt gataacacca
   576481 ctttggtggg ttaaattaat aattgctaaa gatttatttt aataaatctt tagccttagt
   576541 tgtatctata ttacttttaa cactagattc tttagtcaat aaagaacgta ctaaaaagaa
   576601 caaccctaga actaaaaata taaaaggcgc aaaccataat aaataagtat ttttattaac
   576661 tggtggttta aatacgacaa aatcgccata tctatcagtc ataaattgac gaatatcgtt
   576721 atctgtattt tcttccaata ttaactccat gactttttcg cgcaaatctt tagccaatcc
   576781 tgcatttgaa ccaccaatac tttggccttg acaaactggg cagcgaattt cgttaattaa
   576841 cgtttgataa cgttgttgtt gattattgac ataacttttg gcttcaaaac tatcaacatg
   576901 agtataacta acaaatccta ataggaataa aatcgaataa aataacacta aaatataaat
   576961 tttattaaaa ataataattt taacctatgc cattgattac acttgacaat atttctctta
   577021 gtttttctga caaacaaatc ctaaataaag taaattcaac catatataaa ggcgacaaaa
   577081 ttgcacttat tggtagaaat ggtgaaggaa aatctacttt tatgcgcatt cttgctggtt
   577141 taattgaatc agatgacggc aaactaaata ttaaaaatgg cagcaaaatt agttatttag
   577201 aacaaacact accacaaaat aatgataaaa atttatttga tattgtggca gaaggtctag
   577261 gagatattgg cattattctc acagaatacc aacatttaat taataatgga aaattagaac
   577321 aagctagtaa agtacaagaa aaaattgatc aatcaaatag ttggcaatat ttgtataaaa
   577381 tacaaaccat tctcaatcgt tttacactca atgctaatac aattttgtct acgctttcta
   577441 gcggttggaa aagacgtgta atgctagcta gagcattaat tcaaaatcca gatgtattat
   577501 tacttgatga accaactaac catatggata ttaccactat tcttaatctt gagcatatgc
   577561 taaagaatta taatggtact ttagtactaa ttagtcatga tcgttcattt attaaaagca
   577621 ttgttaatcg tgtatttgat cttgatcgtg gtaatttagc agtatttaat tgtagctatg
   577681 ttaattatgt taaacgcaaa aatatacaac ttcatactga aaaaattgcc aacgcacgat
   577741 ttgataaaaa acttgcacaa gaagaaaatt ggattagaca aggtatcaaa gctagacgaa
   577801 ctcgcaacga aggacgtatt cgcactttaa aatctatgcg taaatcattc acaaatcgtc
   577861 gtgtgaaaaa aagcaatgct aacatacata tcctgaatga tgaaaatcat atttccaaat
   577921 tgattttcga aattaaaaaa attaattacc aaattgctgg cattaatcta attgaaaatt
   577981 tttctatgct aattttgaaa ggtgaaaaaa tcggtattac cggtagtaat ggtacaggaa
   578041 aatctacttt cattgaactc ctacttgata aattacaacc tgatagtggt tccattctta
   578101 ggtcaaaaac tattaaacta gcctactttg accaaacaca gtatcttgag cctagtatga
   578161 aagtcatgga tttcgcttct gaaggtcgtg agcatattga tattggtgga aaaagtaagc
   578221 atattattgg ctatctacgt caatttttat ttactgaaaa acaagccatg gcaccgatta
   578281 gaatgctttc tggaggcgaa aaaaatcgcc ttatgttggc taaaatttta tctcaacctg
   578341 ccaatttatt agtgcttgat gaaccaacta atgaccttga tattgaaaca cttgaattat
   578401 tagaggaaat gttagtaaat tataacggca ctttgctttt aatttcacac gatagaactt
   578461 ttttaaacaa tgttgttagt tctacaattg ttatgaatga tggtattatc aaccaatatg
   578521 ctggtggtta tgatgattat ctgactaaaa aacaagataa attatacaaa accaaagtta
   578581 aaacaactaa aaagtttaaa taaaaattta ttgatttcaa ttacacatta tcacactatg
   578641 gatttttaca acagaaaaaa tcttaagata tcttaattaa acctatcaag ttaaaaacaa
   578701 aatttgaaag atattataaa agaatagaga agatttaaat gacaccatta attgtcgact
   578761 tggaccatac attaattgat acagatttat tgtatgagtc ttcaattggt acattaaaaa
   578821 aaaatccact acttattttt atttatcctt tttggttttt tcgtggaaaa ggctatttaa
   578881 aagaacaatt ggctaaacgt tttcctattg atattaaagt tttagcttac aatcaagacg
   578941 taattaatta tatcaaagaa cgcaaagaac aaggagataa aatcatactt gctactgcct
   579001 cgcataaatt atatgcttct gccgttaaca atcatctgaa aactgaaaaa actcagataa
   579061 aaaataaaca gaaaaatttt aattttttta tccataacga tcaacaaaca accgttaata
   579121 aaattaattt attcgatgat gttatggcaa gtaacaaaaa ctttaatcta tcttcacaca
   579181 ataaagcaaa acgattaatt gagcgatttg gcaataaagg ctttgactat ataggtgatc
   579241 atatgcgtga tttacccgtt tgggaagcat ccaatctgtc aattttagtt aatgtaccaa
   579301 ataaaattat taataaaacc aaacatctta atacgttagt attatcaaga aagaattaag
   579361 aaacaaagca tatcaattat ctttattata tagccaaaag aagataaggt attaactaac
   579421 aaaaacaaat tatatagtta tctttggtat tttttatttt taataaaata tcaaattatt
   579481 gaacaattat tatatcgtca aatcccttca attaaatatg ataaaacacc aaagaacaag
   579541 tatataatac taattacgct aagtgtaata gtaattactt tagctatttt taaattttta
   579601 cctaaaatcc gattgttaat ccaccacaca aaatagctaa caacaaaagc aatcacaagt
   579661 atcctaataa acatattaat cttttagttt ttcaactatt ttagtcgcta atattaaatt
   579721 aatacaacta actttttgaa tttcatgaat agatgctttc tttacttctt gtaaaccaac
   579781 aaaataatta agtagaccta ttctacgtaa ctttactact cctataatag attctaatat
   579841 tgaagttata catcttaaaa acaagttttt tcgataattc ttcattacaa aactgatgat
   579901 tcattccgga ttcgattcac taacataaaa gtaagaatat ggttaggcaa cttgtctaac
   579961 tctaaaataa ctttgtaggt gcacaagtct tgatttttta aatcttgata ataacatttt
   580021 gattaagatt ttccttaacg gttaaattag ctatattaag ataatgtctt tatatttatt
   580081 tagtctgtca ataatatgcg tatttaaagc tgaagaaatt atatgtttat cattcaattt
   580141 ataactaatt aatatttgtt tagggatatt tttatctaaa tagtataaaa gcaaaaaagc
   580201 agataaaatt tgtttaaaat ctagattatt tgagtttttt ggtaaaataa atacctattc
   580261 aatttgttta ccagaacgtc cttaatacca cttactcctc attgttgatc aatactaacc
   580321 acatataagt tactactaaa acttgatata gttgttattg aataacgtgt aaatcaatta
   580381 attggtaata taatcgcgcc gctaattcaa actctaaatt ttgagaagca agttgcattt
   580441 tttttgacac cttttctaga gttttcttgt ctttgtcaga taagaataaa gacatcattg
   580501 gtacatctaa ttgataattt tcatatggct gatttttccc acacaaggtg tactacatag
   580561 ccatatttga tattataaac aaagtctaaa cgagattcag taagttctat tagagcattc
   580621 tctaacttta aaaattttaa tatttaccac caggactcta gttttgttct gtttatgtgt
   580681 tctaacaaaa tagtttaaca ctctactttt taagttttta gctttaccta catagattat
   580741 ttaatcctgt ttatcaaaca tttgataaac accagagttg gtagttagat tctttagtct
   580801 tttctttaat tggtatctat acaaaaaaca cttacaaagg taaaattcaa attaggttaa
   580861 ttttttttaa aatttgtgat taaaacatta ctcattgtat tgtctatttt gcctataaat
   580921 tctactttag cgatagacaa agttctaaat acaactcatc aagcaatcgt agatatgatt
   580981 gacccgccta attcagccgc gcttaatatt atggttagcg ctctaacttc tttaaaagaa
   581041 ttaaaaaaac aaaaaagagc cactaaaaaa aatattgaag ctttaactcg attaaaaatt
   581101 ttacctaata ttgctataag tgtatccact aaaattgcat taaacaaata ttgggataac
   581161 ttaaatatcc aacaaaaaca gttttttaaa tactatattt cagaatcttt aatccaagat
   581221 tatgtaggta tcttatccag ttacgacaaa cttgatagcg tacacatttc agtagatcct
   581281 gacgttaaac gtaaaaatga taaggctatt gtaaggttaa ttattaatat taataatgat
   581341 ccgaaaccta gtatcatttc tctaaaaatg atacgattta atacttggcg tgtgtatgat
   581401 atcgtatttt ctggcataag tattgttaaa aattatcgcg ctcaatttaa ttcatatatt
   581461 agacgtaagg gtattgacag cctaattaga aaatctaaac agaagcttaa aaaaatagct
   581521 gaataatgta caaacttatt attcatggcg gtatctcgtt aaatggtagt gttataactg
   581581 cgggatcaaa aaattcatct ctacccatct tatttgcctc aatattagct aatggcccta
   581641 tcactttaac caatacacct catttaagtg atgtttcaac cacacttaga ttattaatgg
   581701 atatgggtgc agaatttata ctagaatcag ataattcttt atttataaat ggttctaaat
   581761 taacaaactt agtcgctcaa tacaatttgg ttaagactat gcgtgcttca attttagcat
   581821 tagggccaat gcttgctaaa tatggcaagg caaaaatatc tctacctggg ggttgtgcaa
   581881 ttggcccacg tcctgttaat ttacacttag aagcattaga aaatttagga gcaacaatta
   581941 aagtcaaaaa tggttatatt tatgccacag ctaaagaact tattggtact aaaattcatt
   582001 ttaaacaaat ttcagtaact gctactgaaa atataattat ggcagcaact ttagcaacag
   582061 gtataactac aatttataat gctgcacaag aacctgaaat tgtagattta gtcaaatgtt
   582121 taatcaagat gggggctatt atttccggtg ctggtacttc aattattatt atccaaggag
   582181 ttgatgaatt atcaggcgta acttattcag tttgtcctga tcgaattgaa gcaggtactt
   582241 atcttgttgc tacagctatc acaggtggta aaattacgat taaaaatgtg cattatcaat
   582301 caatgcatgc cattctcgaa aaactacttg aaaccggcgc agacattaaa actaataaaa
   582361 attcaatcat ccttgatatg aaaggaaaac gacccagagc tgttaatatc aaaactagta
   582421 cttatccaaa ttttcccaca gatatgcagg cacaatttac agcacttaac gctattgctg
   582481 atgggtatag tactattact gaaaccatct ttgaaaatag atttatgcac attcctgaat
   582541 tatcacgcat gggcgcaaat cttgttttaa aaggtaacac tgttgtttgc aaaggggtaa
   582601 aatatttaac tggaatgccc ttaatagcaa ctgatttaag ggcttcagca tctttagtgt
   582661 tagctggatt agtagcaacg ggtaccacaa cgattgaacg tgtttaccat ctagatcgtg
   582721 gttatgaaac aatcgaggaa aaattaaaac tattaggtgc tcaaattgaa cgtgtacagg
   582781 attaaaaatt tatgctaact atcacattat ccaaaggtag aattttaaaa caaacattac
   582841 ctttacttga acaagcaggt ttaattattg ctaaacaaga gttaaactca cgtaaattaa
   582901 ttcttgatac caatctcact gacgttaaag ttattattgt tcgttcaact gatgtacctg
   582961 tatttgtaca gcatggtgct actgatatgg gcattgctgg taaagatgtt ttacttgaac
   583021 atggtgctaa taatctattc gaagtgctag atctaggtat tgctaaatgt aaactaatgg
   583081 tagctgctga gtcaaaaaat agacttaaac aaaatacact taaagtagca actaaatatg
   583141 tcaattcaac caaacgttat tttcaaaata aaggtcaatc ttgtgaaatc ataaaacttt
   583201 acggtgcaat ggaattagcg ccaaaagtcg gtctagctca ttgtattgtt gatttagttg
   583261 atactgggaa taccttaaaa gccaatgggc ttatcccatt tgagtatatt gaaaaaatta
   583321 gctctcgttt agtggtaaat gtcgcttcat ttagaaccaa aaatgcacaa attaagtctt
   583381 ggattcaaaa tattgagaac agtttatgat cactaaatta gtatctacac aatttgactt
   583441 tcaaaaaaag ctctcctcat tacttgaatg ggaaaatgtt tctaactcca gtgttaccaa
   583501 aacagttagc gatattatta ctaatattcg tagtaatggt gatagtgctt taattgatta
   583561 cacgaataaa tttgataatg ttaacgcctc tagcatgaaa gatttaacta ttgaattacc
   583621 tagactcaaa caagcctttg acatactcga tgaaaaacaa aaatctgcac taagcacagc
   583681 ggcaaaccgc atacgtcttt accacgaaaa acaaaaacaa agtacttggt cctatacaga
   583741 agatgatggt acagtgctgg gacaaaaaat tacatcacta gattgtgttg gtttgtacgt
   583801 ccctggtggt aaagcagtct acccttcctc tgtattaatg aacgctatcc cagctaaagt
   583861 tgctggtgta aaagcattaa ttatggttgt accaacaccc aatgcaataa gtaattcatt
   583921 aatattagca gcagcacata tttcaggtat tactcaggta tttacaatag gaggcgcaca
   583981 agcaatcgca tcgcttgctt atggtacaca aaccatacct aaggtagata agattgtagg
   584041 acctggtaat atttatgtcg caacagctaa acgcgcagta tttggtcaag tcggtattga
   584101 tatgattgct ggccctagtg aaatcctcat tatttgtgat gggaaaacta atccagactg
   584161 gattgcaatg gatttatttt ctcaagcaga acatgatgaa aactcacaat cacttttatt
   584221 atctcctgac tctaacttta ttaatcaagt tgagtcaagt attaaaaaac tattgcctac
   584281 tatgagtaga aaaaacatta ttaaaactgc acttaaaaac cgtggagcac tcattcacac
   584341 taaagatatg aatgaggcaa tctctttatc taaccaaatt gcacctgaac atttagaatt
   584401 atctattgaa caccctaaag ctgtattaga taatattaaa cacgcaggtg caatttttat
   584461 gggtcgccac acttgtgaat ccttaggaga ttattgcgca ggaccaaatc atgtactacc
   584521 aacttcaggt acagcacgtt tttcatcccc tttaggggtg tatgattttc aaaaaaaatc
   584581 aagtttgatt atggtttcta accaaggtgc aaatacattg ggaaaaataa ctgtcaccct
   584641 agctaatggc gaagggctac aagctcatgc tcaatcagca cgctatcgta taacacaata
   584701 attaaagagg ataaataata cataattttt atttgttaaa tatcatttga attgctaaat
   584761 caaaaaaatc tatcccttta aatacattgt tgttacacta ttttgataac taaaaaggaa
   584821 acttattact actaatatta gattttttta ttttagaaaa atcaggcatg ccatcactat
   584881 ctaccatttt agccatcatt ttttgcatct ttccaccact cacctttttc atttgttttt
   584941 gcattttttc aaactgttta attagtttgt tgactgcttg aatattcgta ccagaaccat
   585001 tagcaatacg cgccttacgt gaacctttaa ttaaactaat ataactacgc tctttaggtg
   585061 tcatagaatt aatgatagca accattttct tgatttcagc cccgttcact atttgatttt
   585121 taacattttg gggaatttta cctaaacctg gaagtttatt catcatcgct tctataccac
   585181 ccattttttc cgtttgcaaa agttgataac gcatatcaga taaatcaaat tgacctttgg
   585241 tcattttctg aaaagacttt tgcacttttt tatgattaac tttacgtgaa atctcttcta
   585301 ctaacgataa cacatctccc ataccaagta aacgagaaac tacgcgctct ggatggaaca
   585361 gctccagtgc atcaattttc tcaccaacac ctaaaaattt aattggtttg ccgataatat
   585421 gacgtacaga taatgctgct ccccccctag cgtcgccatc agttttagta agaatcacac
   585481 ctgtcaatgg taatgcgtta gaaaacactt tagcagtatg taccgcgtcc tggcccgtca
   585541 tagaatcgat cacaaataaa gtttcaattg gatctacttt tttctgcaag attttaattt
   585601 cattcatcat ttgctcatct atatgcaaac gacctgcagt atcaactaat aaaacatcaa
   585661 aaaactgttt ttgtgcatat cttttagcgt tagccacaat atctgaaggt ttatcattaa
   585721 ttgttgatgg gaaaaaatct acctcaattt gtttggataa tacttctaac tgctcaatag
   585781 cagcaggacg ataaacatca gcactaacta ctaatacttt tttgttttca cgctgtttta
   585841 aataaaatgc aatcttagcg actgaagtag ttttacccgc accttgtaag cctgctacca
   585901 tgataatagc tggcggttga gtttttaaat caagcgattc tactttacct ccaataatct
   585961 tagttaattc agtttcaacc aacttaataa atgtttgtga tggtgttagt ccttgtccaa
   586021 ccttaagtcc taatgccttg atttgcactt tatctaaaaa taccttgatt acttcaagtg
   586081 caacatctgc ctcaagtagt gcacgacgta ctttacgaat cgcctcttta acattggatt
   586141 cagatagttt attctttcct tgtaaaactt taaaactgtt ttgtaggagc tcggttaaat
   586201 tatcaaacat ttttaaataa atataactaa agtatcgtat tatagtactt tatattaatt
   586261 caaaaattaa ttatgctttt atcttacttg gcaatagctt tgtatttcgc tgcaaccttt
   586321 ttactaatac gttattttgt aataaatgaa atccaacacc aacaaactat ttttttatta
   586381 gtaagtcttg ccataattgt acaatcgctc acctttagcc atttttggag tgataaaggt
   586441 attgtttttg gattagcaaa tagcgcctca tttgttgctt ggttaatttc tgttttatta
   586501 tttttgtctt ccttgtctaa gcctgtacac gtattaggaa tattgattta tccattagta
   586561 gcattcacgt tagcctttag tatcgccttt ccagatacaa taaacaaagt tatcccgata
   586621 aatattgctt tacacgtatt attatcaata actgcttatg ccttattagc tctagcagta
   586681 tgccaatccg tattgttaaa tatccaagaa aagcatttac acgcaagaaa aattaatagt
   586741 tttattaata aacttccagc actacaaact attgaagcac tactatttca aatccttaga
   586801 attggctttt atttattaac cttgtcactc ctttctggtt ttatttttgt acaagatata
   586861 ttttctcaac acttaataca taaaactact ctttcaatta ttgcatggat tattttcgcc
   586921 atactcgttt ttggcagaaa agtttttggt tggcgtggga aacaagccat tactagtaca
   586981 caatttggtt ttggtatttt agttattgct tattttggtt ctaaatttgt tttagaaaga
   587041 cttctaactt agaataattt actgtaacta acaagtctaa gttcagtaga aataaacaat
   587101 aaattagact tgatataaca ttcaaaaaga atcgacataa tgattacttg agacagtagt
   587161 atttttttat ttttactata atctttattg cttcttaaaa attaaaatta cctcaacaat
   587221 agcttctaaa tcaagcaatg ataacttttt ttaatccttt atttaaattg tgtttaaata
   587281 aactaatata aaactattat actttagcaa ctaattcatt aaataatgtc ttaactccac
   587341 aaacttttaa taccattacc attttataat tcttgcataa tctacatagt ttcttggttt
   587401 gaacctattt agcagataat tttaatggag tcaaattaga atgaacaatt gttatgacaa
   587461 ataatttaat ggcttgaaga gaattaagcc taatttatta tatcattgtc aattaatatg
   587521 caaaatagct aagaatacct ccttaggaat gtctaccctg cccacactac gcatacgttt
   587581 tttaccttta ttttgtttat caagtaactt tttcttacgt gaaacatcac caccataaca
   587641 tttagcagtt acattctttc tgagtgcttt cacgtttgaa cgtgaaataa ttttagaacc
   587701 aatacaagct tgaatagtaa catcaaacat ttgtcttgga ataagctctt tcattttttc
   587761 aaccaactca ttccctttac gtacagaatc atctcgatgc ataataagtg ctaacgcatc
   587821 tactggttct tgattgatca taacatccaa acaaattaaa tcagattctt gataacgttc
   587881 aaaatgataa tccatagaag caaaacctct tgatacagat tttaatctgt caaaaaaatc
   587941 aagcaccact tcatttaatg gtaactcgta gataagagat acttgcctac tcatatagat
   588001 gatatttttt tgtataccac gcttttcaat acacaaattc attaccgccc caacatattt
   588061 actaatcact agaatttttg ctgtaataat cggttctcta aatttagaaa tactttgatt
   588121 agttggcatt tttgataggc tgtctactct atggataatg cccttagtat caagaatttc
   588181 ataaataaca gtcggtgcag tgataattaa atcaagatcg tattcacgtt ctaaacgctc
   588241 ttgaacaatt tccatatgta ataagcctaa aaatccgata cgaaagccaa aacctagtac
   588301 gtctgaattt tcaggttcgt attgtaaagc cgcatcattt agacgaagct ttgccaaagc
   588361 atcacgaaat ttttcataat ctttaccaga aattggaaaa atacctgcaa atacacaagg
   588421 ttgcactggt ctaaacccct ctaaagactc tgatgcagga ttttcagcac tggtaatcgt
   588481 atctcctact ggagcaccat caatattttt aatattagca attaaaaatc caacttcccc
   588541 tgcttttaaa ctatctattc ttttacgttt tggagtaaag attccaactt catcaacaat
   588601 gtattcccct ccatttgaga aaatttttat tttagtttta attttaattt caccatcaat
   588661 catacgaatt aaagatacta cgcctaaata actatcaaac caggaatcaa taatcaaagc
   588721 cttaatcggt gcattaatat tgccttttgg agtgggaatt ctttctacaa tttgttctaa
   588781 aatatcttca ataccaatac ctaatttagc actagcatga actacatcat gcgcttcaac
   588841 accgataaca tcttcaattt catccattac acgttcaggg tctgctgctg gaaggtcaat
   588901 cttattaagc acagacacaa cttgtaaacc ttgttctaat gcagtatagc aatttgcaac
   588961 tgtttgcgct tccactcctt gtgatgcgtc aacaatcaat agagctcctt cacaagcaga
   589021 aagtgaacga gatacttcat aagaaaaatc aacatgacca ggcgtgtcaa taaaatttaa
   589081 ttgataagtt tcgccatttt tagcatggta atcaagcgta acactttgcg atttaatagt
   589141 aatacctcgt tctttttcaa tatccataga atctaacact tgagatgaca tttcccgatc
   589201 actcaaaccg ccacaaaact gaataaagca gtcagcaatg gtcgattttc catggtcaat
   589261 atgggcaata attgaaaaat tacgaatgtt tttcatatga taaaatagat ctttttaagt
   589321 atattattat acagtcatga ataaagttca accaattacc tgtactgcta caagcaattt
   589381 aaaaataagc attcctgata ctaaagggcg taatattgta ttgtattttt atcctaaaga
   589441 ttccactcca ggatgtatta ctgaagggca aaattttaga gataaacatc aagcattttt
   589501 agatgctaat acagtaattt atggtgtatc aaaagatgat ttaactaaac atgaaaaatt
   589561 taaagccaag caaaattttc cttttgaatt aattgttgat attaatggca ctttatgcga
   589621 attatttaac gtttggcaac ttaaaaagtt tataggtcgt gaatatatgg gcatcgttcg
   589681 ctctactttc ttaattgatg ctaatggcaa tatccttaaa cattgggata aagttaaagt
   589741 taaaggtcac gttgaagaag ttttaatttt tacccaggca ttatgaacaa catagatttt
   589801 aacgaagtta ataaattcgc tactttggca tcacattggt gggataaaaa ctctaaattt
   589861 aaacccctac atgatattaa tccactcaga ctaaattaca tcaaacaaca acataattgc
   589921 ccgctcaagg ataaacaaat tcttgatatt ggttgtggag gtggtatatt aacagaatct
   589981 tttgctttag agggtgcagt ggtaacaggt attgatatgg cagaagaggg cttagaagtt
   590041 gccaaattac acttacttga atcaggctta aaagtagatt atcaaaaaat ttatgtagaa
   590101 aaatttgcta ggcaaaacac taaaaaattt gatattatta cctgcttaga aatgctagag
   590161 catgtaccag atccaggttc aattattaaa gcttgtggtg aattagttaa acctggtgga
   590221 caagtattct tttcgaccat caaccgcaat gctaaatcct atttatttgc cattatcggt
   590281 gcagaataca tcctaaaact cttacctcaa ggcacacatg actggaataa atttattcaa
   590341 cctagcgaaa tagacaaatg ggcaagagcc tcgtccttat ctcttaaagg aatgaccgga
   590401 atagtataca acccctttac aaaaacatac aaacttaaag acgatgtaag tgtaaattat
   590461 ttatctcatt atcaaaaata aagaaataaa ccataaaaac tacaggtaac caaaaaatga
   590521 aaataatact cactcttcta tttcttacta gcaattttag tgcattagcc ctctcaccca
   590581 acgaaatgct ggtaattgtt ggcgcagtta aatactacaa tgaaaattgt tcaggattga
   590641 attcagcagg atttcaacga atgaacaaag gattaaaacg ctttaaaatg aataaaatcc
   590701 ctatacctat actggaacaa cagctactag ctatatctag ctatcaaaca gcaaaaaaat
   590761 ttggttgtat taagactaaa aatgaagctt ataaagcagg gtttggtcaa tatataaatt
   590821 aattttctat ttctaaaatt acaaatgcca tagcattaaa tttttcatct gacaaactaa
   590881 gatgtgcctt tttaatattt ttatccacca aatacaaaca caattttgca ctgaaaataa
   590941 aatagggatt accctgttta ttattgcaaa tagttaaatc ttgaaaactg acaatcttac
   591001 caatacctat acccaaagct tttgcaaaag cctctttagc ggaaaaacgc ttagcacaat
   591061 aagtgctact atcgcctttt ttagcaaata aaacttgttc atattcagat aatacacgtt
   591121 taacaaagcc ttctttattt ttgcttaaga tacgttcaac acgttcaata ttgacaatat
   591181 caacccctac accataaatc attgtcttgc atcaatcatt aaatttttca tctcttggat
   591241 tgcagttcca agactcacaa atattgctct ggaaataatt gagtggccaa tattaagctc
   591301 aacaatttca ggtaatttag caatattagt tatattaccc aaggttaatc catgtcctgc
   591361 attgacttgt aaaccaattg aacgtgcata ggttgccata attttaattc tttcaagttc
   591421 tgttaattgc gcctcattag ttgcattagc ataatgacca gtatggagtt caactacagc
   591481 tgcaccacac tgtttagctg catcaatttg atctttttgt gcgtcaataa ataaagaaac
   591541 aataatattt gacattttaa gttgaatgca aatatcacat atcttagaaa tttgagatgt
   591601 tacgtttagt ccgccttcag tagtcaattc ctcgcgtttt tccggtacta gacaacaatt
   591661 ttgaggttta atcttactag caatggcgat catttcatcc gttgctgcca tttctaagtt
   591721 catttttgta gttaacttac cacgcaaaat ttcaacatcg gcatcttgaa tatgacgcct
   591781 atcctctcgt aaatgtaaag taatgctatc cgcgcctgat ttttcacata ataaagctgc
   591841 ttctaccagt gaaggatagt ccgtgcctct aacttgccta atggtagcaa tatgatcaat
   591901 gttaatacct aaataaatac ccattgtttg ttatggttga ataaaaaata aagaccgact
   591961 tttaaggatt tatcgcctaa aagtgaatgt aatagttgtt tatttaaatc atgataaatt
   592021 tttattggta agtggtaaat cactttctcg atattttacc aaaagaatta ggtataaatc
   592081 ctactttagg ttgatattaa tcataattat ttaagttaat tttattacca ttaatatcaa
   592141 ttaactaatg tattatcact tttaactcac tattttccta caaatagaat acttaaatat
   592201 taaaacattt gaatatgggt ttttaattct ttaagtctct ctgtcaacta agcgaaaaat
   592261 ttaccaaaat tacagaaaaa accaagtagt aatgataaac ctttaaaaat aaacatgata
   592321 aatcagaaaa aacaacaggg ttaattcaac tttagtcata ccctaatgaa gccagtgcac
   592381 gcttatcatc agaccatcct tgtttaactt taaccctaag tttgaggaat acttttctat
   592441 ctaaaaatcc ctcaatactt tttcgtgctt cagtaccaat taattttagc attacacctt
   592501 tattgccaat aacaatattt ttttgtgaag ctttatcaac aaaaatatga gaagcaattc
   592561 gttgtaaatt tctatcttgt tcaaactgtt caatttcaac ggttaaatcg taaggcaatt
   592621 cgtcttttaa atggcgcata agtttttctc gaataaattc agcaacaata aatttttcac
   592681 ttctgtcggt tatataatca gcatcaaaaa taagagtttg ttttggtaaa tattgcaaaa
   592741 ctaattcacg caatacacaa atatcatttt ttttaaatgc tgacaatgga aataaatctg
   592801 ttggttgata tttttgaaaa attttattca aaaatggtaa cacctcttgc ggggacttga
   592861 gtttgtcaat tttgttaata cataaaataa ctggaacatc tatctgagta atatgttcta
   592921 aaactctcaa gtcctctttg gtccatttac ctacttctat taaccataaa ataacatcaa
   592981 catccattat agctaaactg gctactctat tcatataaga attaatggct ttatagttgc
   593041 ccatatgaat tcctggcgta tccacaaaga ccatttgata attatcagtt gtatcaatag
   593101 catgaattcg atgtcgtgtg gtttgtggac ggtgtgaagt gatagataat ttacgcccaa
   593161 ttaattcatt aataagtgta gatttaccaa cattaggtct cccaacaacc ccaataaaac
   593221 ctgacttaaa gtttgattta gtaattttat tgtttatttt aatcatgatt tttttaattt
   593281 ttttaataaa atttgtgcac aaaattgttc tgctttttta atgcttttag cagattgctt
   593341 aacttgtagc ttttggtctt ctaaaaaaca atttaccata aatattgcat tatgatcttt
   593401 tcctgttgta tcaattagtt tgtattttgg taaaatatta ccacgctttt gtagatattc
   593461 ttgtaattgt gtctttgagt cttttagcga atcatctgga ctgatactat ttagcaagac
   593521 tttaaaaaga cctaagataa ccatattagt ggtttcaaaa tttgaatcca ataacaccgc
   593581 accaaatatt gcttctacag tatctgcttg aatagattca cgcctataac caccactttt
   593641 taattcacca gaacctaaaa tcaaattgtt tgatagttct aatgcagtac ctaactgtac
   593701 caaagtttga cctctaatta agtgtgatct taatcgggaa agttttcctt cgtcaacaca
   593761 aggaaaacgc tgataaagtt cttttgagat tgctacgcct aaaatactat cacctaaaaa
   593821 ttctaaacgt tcattattgt ttcttccagt agaacggtgt gttaatgcaa gttttaataa
   593881 agacaagtct ttaaattgat aattaatttt tttttgtaat tttttcatta ctttgtatta
   593941 ggttttataa acgagtaatg tgtttataat acattctgat tataatttaa gattttttat
   594001 gttttggcaa gaagaagcta aaaaagaaca ttttacgctg cctgaaacca tacaagatgt
   594061 agtgtttaat atcttctcta atattttacc tattgatcat agttttttac tagaacaagc
   594121 gctacttaaa cacttaccat ggcttaatga ggtagatgct ggtatcttta atatcagtgt
   594181 agctgatggt aatggctggg tacagaatca taaaaacgga ttttattacc cttccaaacg
   594241 ctcaaaacta attattagat tgccaaaaga taagcttaat gaaacaaaac agctacttgg
   594301 taaaacacta tatttagata aatatgaaat aaaaattatt aaatttttaa aacccaaatt
   594361 actcagtgac atacctatac tatttgcaaa aaaaattgtc tgtaatgaaa caatgagtga
   594421 aaatgatttc ttacaagatg cttttgaaca attaaaaaca ctcgatattt ctgttaagaa
   594481 aatgatagtt ggtcttaaaa atcacattaa aactgatact aatattattc atacacgttc
   594541 tctaatggtg gctgatctaa aaaaatacga atcaataaca ctacaagaaa aaggccttgg
   594601 taattatcga ttattaggct gtggcttgtt tattccccat aaagatatca caagtatcta
   594661 actttcacta aaagcatttt agtattaata gttaaacctt taaaagcaga ataattttct
   594721 aggtttcaag ataattgata aagtgcctat ttagtttaaa gtttatttta taaattcttt
   594781 gaagatttag aaaagaaaat aaagagtgat aatttacttt cataaaaatg gttatcatta
   594841 ttgtggtaaa ttaattaaaa ataactttca taacatatct ttagttacta aactataaaa
   594901 aatttaacgt cattagaaac aaatatatta aacaaaatag atttagtata caaagtatta
   594961 caaaatatat tgaatgattt agattgcaac tggtgcttta ataggtgcat caaatatata
   595021 atttacaaac tcaaagtcct cgaaactata atcaaaaata ttctcaggct tacgcttaat
   595081 tttaagtgtt gctagtgctt ttggagtacg agataattgt atttctactt gtttataatg
   595141 attggaataa atatgacaat cacccccact ccagataaaa tcacctactt ctaaatcaca
   595201 ctgctgcgcc atcatatgag ttaacaatga atatgaagca atattgaatg gtacaccaag
   595261 aaaaatatct gcacttcttt ggtacaactg acaagataac tttccatcag ctacataaaa
   595321 ctgaaaaaat acatggcaag gcggtaatgc catattttct aactcaccaa cattccaagc
   595381 tgaaacaata attctacgag agtttggtgt atttttaatt tgctctacca ctttcgaaat
   595441 ctggtcaata cttttatctt taatattttt ccaatgacgc cactgtgtgc cataaactgg
   595501 gcctaaatct ccattttcat ctgcccattc attccaaatt ctaactccat tatcttgtaa
   595561 atatttaatg ttagtatcac cattaagaaa ccacaataac tcgtatacaa ctgaaggcaa
   595621 gtgtacgtgt ttagtggtaa caagtggaaa ccccttggat aaatcaaaac gcatttgata
   595681 tccgaacata cttgttgttc ctgtattcgt tctatcggtc ttatataccc caatattttt
   595741 aactagcttt agaaaatcta agtactgttt cacattattt cctttttaat atatgctttt
   595801 cgcaatagga aaataccaac taatatcatt ggtaagctta ataattgtcc catggtaaac
   595861 caaccaaaag ccaaataacc taactgtaca tctggtaatc gaataaactc aattataaat
   595921 ctaaataaac cataaaaaat taaaaataat gctgaaattg acatagatgg acgcaattta
   595981 ttactaaata accaaagaat aataaataaa attaagccct ctaaaaacgc ttcaaccaat
   596041 tgtgatggat atcgacttac actttgttgt tcaatataca ttccaaatgg gctggtagtt
   596101 atttgacccc aaagttcact attaataaaa ttacctatcc taccaaaacc taatcctaaa
   596161 ggtacaagtg gtgctacaaa atccattgta gtaaaaaaag ttttattata ttttcgatta
   596221 aataaaacca ttgccaacaa cacacccaag aaaccaccgt gaaacgacat tccaccatct
   596281 tgaatggcga aaattaacaa agggtccgat aaaaaattta aaaaattata aaacagcata
   596341 tatcccaaac gaccaccgct aaccacacca attgcaccat aaaaaattaa atcttcaatt
   596401 tgttgagtat tccagttgtt aagttgcttt tgcttaacac gataattcgc taataaataa
   596461 gctactaaaa aagccattaa atacatcact ccataccaat agatttgtat aaaacccaaa
   596521 tctagtgcaa ttggattaat aattggatag gtcatattta gtattcctaa tggtacgccc
   596581 gaggtgattc gaacacccga catttagctt cggaggctaa tactctatcc aactgagcta
   596641 cgagcgtata aataaaatcg ttaaaattaa accccttcag aacagaagac tgcttgtata
   596701 ttagacacta attttagaac ctttgtatct ttaattttgc ataaaatttt attaccatca
   596761 cgccgagatt caacaatatt tttggttcta agaatatcaa tatgttgtga gatattagat
   596821 tgtgaagaac caactttgtt tacaatttcc aatacaggta attcatcatt cttcaatgca
   596881 catagaattt ttaaacgcaa tggatgtgcc attgctttta aagctcttgt tgctttttcg
   596941 atatcttctt ccttttctaa taatgctatt tcacccataa ttaattaaag tctacccaac
   597001 ataccataaa taccatatcg cctaactttg attagtatca ttttttgata aaagttgatt
   597061 aagctatcat tattaaatat aatatcaaag atttgccatt tcttatcttt attttgatga
   597121 aatagcaaat caagataaat accaccatac gaagtatatc ttttaacttt aagttgtact
   597181 gcaattgcat cactcatcac tggtctggca gatataaatt gaaacgaagt agaattcact
   597241 tgggataatc tagctaataa agttgtcatc atattatctt tcaatctatt aacaaaaaac
   597301 ttagtctctt tttcgcttaa gcgattatta gttaccagaa aagcttcatt agcaatgtga
   597361 ttaaagtcaa acaatggtgc aatctctttt tcgacaaaag aattaagcat tcttggcgaa
   597421 tataccattg atattaactg attaagtttt acaattgccg tttgtatagc ctgaactggg
   597481 ccactattat cttgtactac tttttctgca gaggctccta atgaaataaa cattatcaaa
   597541 gctaacaaaa ttatatttaa tcttctcatt ttttctccat tttttaaaaa caaaaccaag
   597601 taaaattaaa aaaatagtat tggtttcaca gtattatatt taaacttttt ataagtaaac
   597661 gattatatta tgactttctt aaactttctt aaatattcac tatttttaac acttttttat
   597721 acaactttag gtgtttatac accggcatta gctaaaaatg atactgaaaa acaaaaaata
   597781 gaagattttt tcaaagactt agagatattc acagctgttt ttagtaatat taagaaacta
   597841 tatgttgatg atgttgataa taaaaaacta tttaactatg ctattaaagg tatggtaagt
   597901 ggattagacc cacattcagc ctaccttgaa ctcaaagagc agaagagctt acttgaaagt
   597961 gcttcaggta aatttggagg ccttggtatt attattggta tgaaagatga agctattcaa
   598021 gttatctctc ctattgatga cacacctgcc tataaagctg gtattcaagc gggtgattta
   598081 attgtaaaaa ttaacaacaa agcagtacgg ggtatgactt tagaagatag tgttgaattg
   598141 atgcgtggta aagcaggcac caatgttcaa attaccattg tacgtaaaaa taaaaagcca
   598201 tttattgttg atattattag agaaataatt actattattt cggttaaggg atatttattg
   598261 gaagagaata ttggatacat acgcatctct agctttcaaa acccaacagc acaactactc
   598321 aaacagattt ttaatgactt agttaaagaa aataatactc aacttagttc attaattctt
   598381 gatttaagaa acaatcctgg tggtgttctt aatagtgcag ttgatgtgtc aaatttattt
   598441 cttgataaaa aaggtctagt agtttatacc aaaggtagaa ttccaatttc aaaccttaaa
   598501 tttaaaatta aatcaggtga tattatgcaa ggattaccta ttgttgtact aattaatgaa
   598561 ggttcagcct ctgcatcaga aattgttgca ggtgcattac aagaccataa aagagctatt
   598621 attatgggta ctacttcatt tggaaaaggt tcagttcaaa ctattcttga atctcaaaaa
   598681 gggcacggac ttaaacttac aactgccaga tattacaccc caaatgggcg ttctattcaa
   598741 gccaaaggta ttgttcctga tattgaacta aaaaatatta atattcaaaa tgaagtagaa
   598801 aaatcaataa tcgagactaa agaaaaagac cttgatggtc atttagaagt tgaaaattct
   598861 tctaaagaaa tattaagtat ccaaaaacaa aacaaaacaa aacaaaacaa aataattatt
   598921 aaaaaattgg aaaaagatta ttttatacat gaagctaaga atttattaaa agctttaaca
   598981 attataaata atcagaaata aaaattacat ttcctttgca aaccaaaaaa attaatgtga
   599041 gtaaaattat gataactatt aaattcatat agcaccaatt acttattatt atcatcacaa
   599101 ccatcaaatg caacgataga ttacggtgta tatcaatata accctaatta ttctaatatg
   599161 aataacatgt attatttcaa tatttttcac acaagatata atctttaaac aattatttta
   599221 taaaaataaa attagtagaa taaaaagtgt taaataagat gtaatttact atctaaaatt
   599281 ggttatttct tatatatagc taaaccagtg aaggctaaga aaaacgttaa ttaatatagc
   599341 taaaagttaa aaactaattc atgagttgaa tggattaatt ggaaaagtcc attctacaaa
   599401 tagaaatcat caatcaatgg atgaagtaaa taatattctc aatcagatta attaatcaaa
   599461 actgcctatt ctatcaagtt ttaaagattt atcccagtgc atccaaatac caaatgcttt
   599521 gccaatgata tacgattctg gcacaaaccc ccaaaaacga gaatcactac tacgagcacg
   599581 attatcgccc atcacaaagt aatgctcttc tggtacagtt agttttatac ttttagaagg
   599641 atgttttgga tctagcaaaa tattataagg gttattattt aataattcac gcttattctt
   599701 aaatcctgtc atggctgaac cagactcaat accttgatat atgccaatat tttcactact
   599761 aatttttaca tcattaacat acaaattatc tacatgataa actatcttat cacctgggat
   599821 accaataacg cgcttaataa aatcagcacc cttatatctt aaattatttt cataattagg
   599881 gtatctaaac acaacaacat cacccctttc aggctttgaa aattcaatga tttttttatt
   599941 taatattgga atactcacac cataattaaa cttcgacacc aaaataaagt cacctgttaa
   600001 taaggttggc atcattgagt tggaaggaat tctaaaaggc tcaataacaa aacctcgaag
   600061 tacaaatacc aataataata ctggaaaaaa ctcagctgac cactgaacta ttttaggacg
   600121 atttaaatat ttttcagatt ttttaaaacg taaaaacaag aaaaaataaa taaatctccc
   600181 taaagttggt cttttctttt tacttgtaat tgatattgtt gtatgattaa aaaataattg
   600241 atcaatagtc acgataataa aagctaaaac caaaaacaaa accaaaaatg aagaaacatc
   600301 ccatgcaaaa aaagaagcag cgttttcaat tgtcataata aaaataagag aattaacaaa
   600361 aagtattatt atataatgat tatattttta attgtatgga gaagaaatga cattagctga
   600421 tttagaaaga gataataatg gttacttaaa ggatcttaac gaatggaatg aggatattgc
   600481 agtagaactt tcaaaagaag aaggaattac cttaacagat gatagcttca aattaattaa
   600541 ttttttacgc aatgaatata tcaataacaa cgccaatcaa cctaatgaac gtaatatggt
   600601 taaaagttta aaggatgatt ggaaaggtaa gttaagcact aaagaattat atgtattatt
   600661 tccaaaaggg cccgcgaagc aagcaggaaa aattgctgga ctacctgaaa ctaaacgaaa
   600721 aggtggttat taatccctct tctatcaaaa ataaaatctg atattgatta aggatttttt
   600781 attgattgtt aattaataat ttaaatatct attaaggttg tatctgtagt ttttagcata
   600841 tgttaaatta ataacagtac caaaacttga tatccataca aagcctatta atgatatctt
   600901 tagcaataat taagttaatc tactatgatt ttaaaattta tacttgatta atattttatt
   600961 aagtatctta tcaaactttt caaaaagttg aaaaattaaa ttcaaatatg aacccacttt
   601021 gtaaattaaa aacaactgta tctacaatca atacttaaaa ttttattaat caatatctct
   601081 aatattttta ctcattttta aaataaaaac tatttcagtt aaaagtccat attcattaat
   601141 aaaatacata aatttttgac aaaattaaga tcaaaataga tataaactat ttatgataaa
   601201 attcttaata ttgaaactta gatatatagt gacttcagac agttatatgc taactaatat
   601261 tagcaagctt atgaaaaaaa ctaaaaaaac taaaaaaaat aagatgatat agcttaaaat
   601321 caatcacgta tagctgaata ttaaaaataa aaagaagaaa atctctaaat tacttccaaa
   601381 gttattgtgt caaaattaaa acaattaatt ttaatacgta ttgatatgta acactttatg
   601441 cactaactaa gctaatattc attcctattt ggtttgcaag ttcaacaaaa tttgggaatg
   601501 aggtttgaac attatctaca tcttcaattt caatagcata atgacatctt aaagaagcaa
   601561 tagcaaatga catagaaata cggtgatcat gatgagattt aatcgtagag ctaggtttcg
   601621 aaaaaacacc acctttgatc ttaataccat cttcaaatac ttcattctca ataccaagaa
   601681 tacttaaacc atctgccatc acttgaatac gatcagactc cttaactctt aattctttag
   601741 cgttagtcag tatagtttca cccttagcac agctagctgc aataaaaata gcagggaatt
   601801 catcaatagc tagtggcact aaatctttag gaatacgaat accttttaat tgtgctgatt
   601861 gaatacgaat gttggctaat aactctccgc caattacaca ttcatttgat aaacttagat
   601921 tagcgcccat taattttaaa atatcaataa tacctgttcg tgttgggtta acattaaccc
   601981 caataagagt tatatctgct tgcggtgcaa ttgatgctgc tactataaaa aatgcagctg
   602041 aagatatatc gcttggcact tgtatgttag ctgcatttaa ctgagcgccg ccagtcaagc
   602101 atattttatt tttattagta tctaatctat aacctaatcc ttttaacatg cgttcagtgt
   602161 ggtctcgtgt aaggatagac tctttaatac aagtttcacc ttgtgcatac aaacctgcta
   602221 acaatatgca agatttcact tgtgctgaag ctactggcaa atcataatta atgcctttta
   602281 atgtttgtcc acctttaatt ttaattggta attttccatc attactttca atcaaagcac
   602341 ccatttgaac taaaggatta ataaccctac ccattggccg ctttgaaagc gactcatcac
   602401 catataattc actatcaaat gtttgtgccg ctaatatacc agatattaaa cgaatagatg
   602461 tgccagagtt tccaaaatta agtggcacta aagatttttt aagtccatta agaccaacgc
   602521 cataaataat aacattatcg ctattacgtt caatcttaac ccccatattt tggaaacctt
   602581 ttaacgttga taatacatct tttccctcta aaaaaccact aattttagta acgccattag
   602641 ccaatgatcc aagcataatg cttctatgag aaatagactt atcaccagga atttttaaat
   602701 taccatacat agaattagat ggatttataa tgaatttact catattttta actactaaac
   602761 caattatctc gtgcagactt agcctcttga aaaagctgtt caagagcttc cgctttatta
   602821 tttttaatta ggtttgatat cttttctaat gttttctgat aaccctctat atgcttaaca
   602881 atttctttag ggttattaat acaaatatca cgccacatta atgcgtctga tgaggcaata
   602941 cgtgaaaaat ccttaaaccc acctgctaca taacgacaag catatggatt attactgatt
   603001 aaataatcca tcaatccata tgctaacata tgtggtaaat gagaggtcat agctaataaa
   603061 tcatcatgtt tcttatcagt cataatttct actttagcac caagttcttt ccacaaacca
   603121 ctcaatatag ctattgtctg aatatctgaa ctttctgttg gcgttaaaac aacacgttta
   603181 tgattaaaca attgagcatc aactgcttca ataccacttt tttccttgcc agcaattgga
   603241 tgagccggaa taaattttgc tggcatttga ccaaatacca attttgcaat ttgtatcaca
   603301 ctacccttag tactgccaac atcagaaata ataaccgatt catcaatatg aggtttaatc
   603361 atctctaaaa tagcttgaaa actatttact ggcgttgcaa taataaccat ttgtacctgt
   603421 ttgagaactt gtgagatatc taaactatac tcatcaataa tacccatttc ttgtgctttt
   603481 ctaagatgtg actcttgtct agaaaaacca ataacagttt taacctgatt agtctgtttt
   603541 agtccggcaa caaaagatcc tccaatcaac ccaacaccaa taatacaaat tctatctatc
   603601 ataagagtga ttttaacgct tctaaaaaat catttgaact attcaatgta atacaatcag
   603661 tgttaaagtt taaatgcttg ataagtgatt gctttaattt aaagtcaata ccataaggat
   603721 aactgtgaat ctcaaatata actttctgta ctctaagtat aatgtctaaa gaattttctt
   603781 tactaataag cctagtgaca tatttcaatc ttagttcact acacaatata gtaatatatt
   603841 tagcactttg gtaaggtttt ataaacttac ctattgaaca aatattcata gcgaaaatct
   603901 ttcaaataag aaagagttat ataaatacga aaaagaaaaa ataactctat taaaaattga
   603961 tattttcata accattaata cgagaattac cttataaaac agcaatagga taagaaccaa
   604021 gcacattaac tttaagcact ctactggcta cttctgttaa tgctaatttt acttttttat
   604081 tatctttgtg cccttcaata tcaattaaaa acaaatattc ccacttaaca ccaggaattg
   604141 gatgcttttc caattgtatc atattgatac cttgttgttt aaatggttcc aataaatcac
   604201 aaagtgtacc agactcatgc ttaatcacaa ctagaagtga agttttacct tcaaaagaag
   604261 tagaaatatt ttcaaaagaa gtagaaatat tttctttacc aagaattaaa aaacgagtaa
   604321 cattaccggc cttatcttca atatttttag caattctttc taaaccatac aaatctaatg
   604381 ccacctctga agcaattgca gcagcaccca cctcatcttt aacaatacaa gcagccaatg
   604441 cgtttgatgc aactgatttt aactcagtat ttggataatt attatttagc caacgttgac
   604501 attgattcaa tgcttgagaa tgggcataaa taaccgtaat tccttgcgac tgatttgcac
   604561 tcattaattg atgttgaatt gcaatttcca cctcaccaca aattttcaaa ttctgagaat
   604621 ataacatatc aaccgttgca ccaatcatgc cattagatga attctcaata ggtacaacac
   604681 cataatgcgc attacccttc tcaacttgat gaaaaatatc atcaatacta acacaatcaa
   604741 gtgtggatac actatgtcca aaatgcttaa gcgccgcctc ttgtgtaaaa gtgccttcag
   604801 gacctaagta agcaatattt aaaggttgtt ctagtgcaag acaggccgac ataatttggc
   604861 gaaaaatata tgccatgtct ttatctttta ataggctgtt atttctttta ataattgaac
   604921 gtaacacttg tgcctcacgt tcaggtcggt aaaaaacact actatcatct gaagcttttt
   604981 tcacttgtgc aactttagct actaattgtg cacgattacc aattagtagt tggatttttt
   605041 tatctaatac atcaatctca tcacgtagct ctgacaatgt tcttttaccc atactgtatc
   605101 tcttaaagac ctctaacagt caatatacct tttacttgtt ttaaattatc aacaattgaa
   605161 actggaatct catgctctaa atcaaccaaa gtataagcaa tattattttt tgatttgtta
   605221 agcatatcaa taatattagc gctagtatct gcaatggttg ttgaaatttg accaaccata
   605281 ttaggaatat ttttatgggt aatagctaat cgatttttac ctgctcttgg cattaatact
   605341 tcgggaaaat ttaccgaatt ggtaatatta ccattttcta aataatctct tatttgattt
   605401 accaccataa ttgcacagtt atcttcagcc tctaccgttg atgcacctaa atgtggaaga
   605461 gcaattactc tatcatgatc ttttttatca tcaattggga aatcagtcac gtaatactta
   605521 actttaccat tattaagcgc aatcattaaa gcctcttcat taacaatacc atctctggca
   605581 aaattaagaa tagttgcatc ttctggtaat aaagcgatac gttctttatt taataaattt
   605641 ttagtatttt caactaatgg cacatggaat gaaacaaaat tactccgtga aaatagctca
   605701 tcaatgctta atacctgttc tacacctgat gataatttcc atgcactttt aatagtgatc
   605761 aaagggtcaa aaccaataac attcatcccc aaagcatgtg ctgcattagc aattttcacc
   605821 ccaattgcac ccaaaccaac aatccctaat gttttacttg gtagctcaga accagcatat
   605881 ttttttttac cttcttcaat ggcagttttt aaattatcaa gtgacaaaca attaacataa
   605941 taccaagctt ggcaaatatt acgacttgcc agcaacattg aactaataac taattctttc
   606001 actgcatttg catttgcacc tggtgcatta aacacaacca cacccttatt actcatttta
   606061 tccaaaggaa tattattaac acctgcacca gcacgaccaa caacttttag attatcgtta
   606121 atttccatat catacatttt tgcactgcgt actaaaacta catcaggatt actcattttc
   606181 gaagaaattt tataattatc tcttggtaat ttatttaacc caatcgaaga aatattatta
   606241 agcgtgagaa ctttaatcat taggaatttt ccttctcaaa tactttcatg aaatttatta
   606301 attcattaat tcccttttgg ggcatagcat tataaatact agcacgcatt ccgcccacac
   606361 tacgatgacc ttttaaggta attaaattat taatagctgc tttttccaca aataaaccat
   606421 taagattttc atcagccaat aaaaatggca cgttcatcca agaacgatat tttaaggcta
   606481 ctggatttga ataaaaatta gaaccatcaa taacgtcata aagtgttttt gctttagttt
   606541 ggttaatctt agctatgaca ctcagtccac cttgttgttt aagccattca aacacacgag
   606601 atgcaacgta ccaagaatat gttgatggcg tgttatacat tgaatcgttt tttgcttgta
   606661 ttgtataatc aaataaaata ggctggttag caaccacact acccattaaa tcttctctta
   606721 caatcacaac tgtcagtcct gcaataccaa tatttttttg tgctcctgca taaattacac
   606781 catattttga cacatcaact tctcgtgata aaatacttga tgacatatca gcaaccaatg
   606841 gcatatctac ttctggcaca taatcaaact ctagaccagc aatggtttca ttaggagtat
   606901 aatgcaggta agcaccatca gggtcaatat cccaattttc aaacacatca atatcagtat
   606961 atttattgtc tgaactattt gtacaaatat ttacatcaca ataacgacta ccttcaacaa
   607021 ttgctttttt agaccaatga cctgtatatg catagttagc cttagttttt ccatgaagta
   607081 agttaatcgg taccattgaa aattgagccg atgccccgcc ctgtaaaaat aaaactttat
   607141 agtgattagg aatattcatc aaatctctta aatcttgttc tgatttttga gccattgcta
   607201 taaaatctgt actgcgatgt gaaatttcca taatcgatgc tttaacatct tcatattcta
   607261 gtaattcgtc ttgcatttgt cttaatactt gtattggcaa catagcagga ccagcactaa
   607321 agttataaac ttgactcatt tctttacaaa ctccttgtta ataaaattta aagtcagacg
   607381 attttatcag aacccagata tttaggctta tctaatgttt accctatatt ataattcgca
   607441 cttaattttg attataaaag taggtgaaaa atcttacact gtctgcgcaa cgatattttt
   607501 gacataagaa attagcctga tacatagtct aaaattctta actccattaa ggatgatatc
   607561 attcaaaaaa ccttatttat attaatactt atcacaagta ttaatataaa tgcagtttta
   607621 ggacctattt ccatttatct taacaccgaa tatcgtacca ataatccggt tattgactct
   607681 attacctcaa cattaagttt taatgaaaat gataatacag agagatagta ttaaaaataa
   607741 tgctattaat ctcaagtttg gtaccaaatt tggttatgta aaaacaactc ttgatatatc
   607801 ttcaaataac aataaaattc aatatgacgc ctgtgaattt ggtgcaataa atagtaatga
   607861 ttgcttaaac gatagaagtt caaaaaaatt aatttgatta ctgaaaataa atttagtgat
   607921 tatggtactc taaattatca cttagccagc ttaatcatag tagaaaacac tacactggtg
   607981 aaattttaga aactttgagt aacgataaat ttaaaagcat agatttaact ttattaaacg
   608041 acattaaatt aaacaatgca ttattaaata ttggtttatc aaaaattatc cagtaaggat
   608101 atctttatta attggcaaaa aaatatatct aacatagata taaatacagg catacgtatt
   608161 tatcaatttt aataaatttg gtaaaagaac aatttatagt ttagggcttg ctaaaagcat
   608221 taaaaatgat atcaaattaa cagctagtta caataacgct tttaatgcac cctctattta
   608281 tcaactaaca gacatgccaa cgctgaatcc agaaatttaa aaaaatattg caattggcat
   608341 agaaaaaaga tataacctag gtttatcgtt tattaaagtt tataaaaata aaattaaaaa
   608401 ttttatagac tatcactata gtaccaccaa tcctcaccat tactctaatg aggacaaatt
   608461 aaatacaaaa ggcattgaat ctatcaattt ccgcaaatat caaatactat caaatcaatt
   608521 ttaatcataa ttacgtcaaa agtgtattaa ataataacaa tacacaaaaa attagaagac
   608581 caaaaaatat cactaattta acgatcaata aacaatacac tcaatttgag ttatacttac
   608641 aagtaattaa caagtcatct agtttaggta taggtaaatt aagacttaaa gctacaccct
   608701 ggttaatcta acaaccaatt atcattacaa taataatact aaactagttt taaatattaa
   608761 caatgtattt aataaaaatt acaaagtcat agatggtttt aaccaactag gtaggatgat
   608821 aaattttgat atcagctatc aattctaaac taatcttcaa ggtaaagaca gtttttatac
   608881 cctgtatttg cttaaataaa actaaatcct atggaaaaaa tgactaactc tacacttttg
   608941 tacatgaccc acaaaaattt gataaactca ttaaccttaa aaaggggcaa tcatataaca
   609001 caatgatttt atctttacca atttgctata atgaagaata ttcacagggt ataaaaatat
   609061 gataaataaa atccacaaaa caaagactat ctttgctatt tttattatgg ttattttaat
   609121 aattaccact cgtggtaaca ttaactggca atcatcaatt attcacctac cagattttac
   609181 tattcctgct ttatttattg caggtgttta tttacgtaca ttttggacag cgatagtgat
   609241 tattataagc gccattatta ttgataatta tacaattatt cacaaaggcg taagtgcaaa
   609301 ttgcattact cctgcttata gcattttact acttacttat tatggtattt tttgggtagg
   609361 aaaataccta acaacactta aaattgacca taatattatt aagaacgcat taattattat
   609421 tattacctgt attactcaat ggtttgttgc taccgctagt tactttgcat ttacaacatc
   609481 attttgggga aaatttggct tatacattgc tcattggtca attattgaga ttccattaat
   609541 attatattgg atgattgcta tttgtagcat ctttacactt aatcatcgct acttaataat
   609601 accttttttc tcaacacgga aagattaaag tttcgtggta gaaaatcatt ataaagctcg
   609661 tatgcaacgt aaaaaatttt atattaatac tcgcataaaa caagccaata ttgacaaagg
   609721 tattattgtt cttttaacag gtaacggaaa aggtaaatca tcatccgcac tgggaatggt
   609781 ttgccgtgca ttaggttata acatgaaaat tgccattgct aaatttttaa aaggagtaca
   609841 aaccacaggt gaagacatat tcttagccaa acaacccaac gtacaaacca catatatgaa
   609901 aacaggtttt acttgggaca cgcaagacaa aacctttgat acagatatgg cacaagaaac
   609961 ttggggcaaa gctgaacaat atttaaacga tgattcaatt aatttggttg tacttgacga
   610021 acttacttat atgattaatt accaatatct ttacgaagca caaattatca acactttaaa
   610081 caatcgccct aaaaaacaac atgtaataat tactggcaga gtcgcctctc aaaagttaat
   610141 taaacttgcc gatacagtaa gcgaaattaa agatattaaa cacgctttta gagcaaatat
   610201 taaagcccaa aaaggcatag aactttaatc aaaacatatt aagttaaaat taatcatcta
   610261 aataaactgg atatttagca caaagactaa cgactcttcc tctaatctta taaatcactt
   610321 cttgattccc taaatcatca caaatatcgc acatccaaga tgctaaatca gaacaatcaa
   610381 tctcattgaa tccacgtgtt gtcaccgatg gtgtacctac acgaatacca ctagttacaa
   610441 aaggagggtt cgggtcgttt ggcactgcat tcatattaac cgtgatatac gcactgccta
   610501 aagcagtatc cactgcttta cctgttaatc cttggtcaat aaaacttact aagaataaat
   610561 gattatccgt accacctgaa actacatcaa atccacgttt aataaatgta ttagccatta
   610621 cttgtgcatt aatctttact tgcttctgat aagtcttata ttcatcactc atagcttctt
   610681 taaaactcac tgctttagca gcaatgatat gcattagtgg cccgccctgg ataccaggga
   610741 aaatagcagc attaagtttc ttttctattg tcttgttaga cttggctaaa attaaaccac
   610801 ccctagggcc ccgaagtgtt ttatgcgtag ttgtagtggt tacatcagca attgcaactg
   610861 gtgatggata ttcaccagtt gcaatcaaac cagcaacatg cgccatatca accattaaat
   610921 aagcaccaac actatctgca atttctctaa aacgttgcca atcaaccata cgtgaatatg
   610981 ctgaaaaacc agcaataatc attttaggct tatacctttt tgccaaaact tcaacttgct
   611041 cataatcaat ctcccccgtt ttttgattca aaccatattg aatagaatta aaatttttac
   611101 ccgaaaacga aggtgtagca ccatgtgtta aatgtccgcc atgtgctaaa ctcatgccta
   611161 aaattgtatc cccaggtact aacaacgctt gaaaaaccgc agcattcgcc tgagaaccag
   611221 aatgtggttg gacattcgca taatccgcac caaataatgt tttagcacga tcaatcgcta
   611281 attgctcaac catgtcaaca tattcacacc ccccataata acgcttacaa ggataccctt
   611341 cagcatactt attggttaat tttgaacctt gcgtctccat cactgcaggt gaagtataat
   611401 tttcactggc aatcaactca atatgtgtct cttgtcgagt ctcttccaga acaatcgctt
   611461 tatagatttc agcatctact ttagctaatg tttgagattt atcaaacata attttcctta
   611521 taatataatg tttaaaacta aaatagttta ttttaataca taaacataaa taaagaataa
   611581 atgattatcc ttaaattcag attctgaatg caattcttta ttagttaata ccttgtaaaa
   611641 catatgatct tagtgtcaaa gaaaatacta agcacaatgt actaataact aattatttag
   611701 tagatattca accaacatgg caaacgccgt ttatcactaa taacaaaatc aaaaaagtaa
   611761 tatagtatga catacaataa atattgagcc aatcaataac acatttagat acttctaaaa
   611821 actaaaaaca gttgtatatt caaaattatt aacgaatcca ttattaccaa taatggtatt
   611881 atattctact tgtatttttt tgcaaacttt atgttaacag aaaacagaac aaacttagta
   611941 tgcaaaataa aattctgaaa actaaaatga ttaaccactt aacataagta tcatcactat
   612001 attaaactat aaaaagttaa tcgctaatct aagcacttac atctaaaata aatattcact
   612061 tagtctatat ttattcacac cgtcttttaa atttatcggg acgacaggat ttgaacctgt
   612121 gaccaccaca cccccagtgt ggtacgctac catactgcgc tacaccccgt gagagcaaat
   612181 tttacaagat tcgtctttat ttattttaat ttttttaaaa gaaagattta aggtatcaat
   612241 taacattaat tttcccacta attgttcgcc taaatttaac aaaactttaa tagcttgcaa
   612301 ggcttgtaat gagccaatta ttcctgtaac aggtgatagt ataccatttc tagtacaatt
   612361 ctcatcagaa tttccttcaa ttgaatataa acactggtaa caaggttttg tttggttata
   612421 gccttgaaat acagataact gtccttcaaa acgaatgact gctgctgata caagaggtgt
   612481 tctttgcatt acgcaagctt tgttaatttt aaatctaata tcaaaattat ctgtgccatc
   612541 taaaactaca tcaactttag ctacccaatt attcagatta tcttgactta gttttccaat
   612601 cgtagtaact tttatattag gattaatagc gagtatctta tctttggcag aattgacttt
   612661 tgttctacca atatcatctg tagaatggat aatttgccgt tgtaagtttg acaattcaac
   612721 tttatcagaa tcagcaataa ttaaatgtcc aataccagca gaggctaaat ataaggcact
   612781 gggtgaacct aaaccaccca taccaattag taataaagta gaatctttta gggattgttg
   612841 ccctttaatg ctgatttgag gtagtaatat ttggcgagaa tatctaagta attcttgatc
   612901 gttcattggc taaagtattt atctaattta ggtctgatta acatttgaca atagggtttt
   612961 gataagttgt tattaaaata attttgatga taatcttcag ctggataaaa gcaatctagc
   613021 tttgtaactt gagttacaat attatcactc ataagattaa tcatattaat tgcttgtagt
   613081 tgttgtttat tatttatata aaaaatagca gagcgatatt gagtaccacg gtcatttcct
   613141 tgttggttta atgtggtggg attatgaatt tcaaagaaaa tatctaacaa tactttaaaa
   613201 gatattttaa actcatcaaa ctctattttg actacctcag catgtccagt tacgcctaaa
   613261 caaatatctt gataagtagg attactggta ttcccattac aataaccaga agtgagttta
   613321 ataatcccca caatgcgttg aaaaattgct tcaacacacc aaaaacatcc accagaaaag
   613381 taggcagttt gcatctataa ttttccattt tatgaattaa aataattagt ataattgatg
   613441 agtagtaata gtattacctc acaattaaaa tagtttacaa ctgagcaaaa gcaaaaaata
   613501 aagtctatta ttagacattt ttaatacaaa tataattaca agaactaata atattaataa
   613561 ttttcttact aagcaatata tgagtaatat tataactaaa tactatgtgt agtataaaag
   613621 atacgaaata ataaaaaata cgaaataata aaaaatacga aataataaaa aatataagtg
   613681 aaaaatagat ttaagcacaa aaaggtagtt cctatgaata ttaataaaaa ctaaaataaa
   613741 tatgcttggc gtggatggtt cattgttttt gattataata ataaattatt ataatcaaaa
   613801 attaaagata tgcttaaaag acttgttgaa tttttaaaaa acaatcatcc agatgccaat
   613861 attgaagaat atttagatgc aaaatacatt caacttaata accttcagct taaacaaatt
   613921 gccaatgcac taaataatgg caaattaagc acaaaacctg catcaaattg taatgcaaat
   613981 cattttattt ttcattttgg ctcaactctt attttactac aaaaagatac aacaaataca
   614041 agtaaggtat atcaggtaga actttcttgg gaaactgact ttttatcgat tagatctaga
   614101 gacaaaacca aaggctttta ttttataaat tttgaatttg acaacaatta caatacaacc
   614161 ctgcaaaaaa caaaaaaaac cattaagggt catattaaca atactgttaa aaatcaagaa
   614221 attattgaca aaataatgcc aatattaaaa ggctttatgt cggctattac agactagtaa
   614281 gtaattctaa atagtcttta ataaaattga ggaattcatg atactgtaac ttataccgtc
   614341 aactattaca aattaacaac aaagtttttt agattatagt ttggaaaata tccatctttt
   614401 tgagtagcta atttaagctt tggtcctgat ttaaacacta ctactctcct agctgaaatt
   614461 tcaaccattt caccagtctt agggttccta cctactctgg aagatttctc tcttatgata
   614521 aaattaccaa aactagatag ttttactgat tctccagaag ctaatgtttg tttgatttga
   614581 tcaaaaaaat catgcgtgat tgataatgct tgaacatgag ttatgtccat gctttttact
   614641 aaaacgttag caatatcttt tttggtaatt gacattatct gagaatagct gaatattgag
   614701 tttgcattaa taccaaaact tcatcaactt tagtattcaa ttgtgtttct gtcagcgtcc
   614761 cctctagtga ttgataagtt aaactaagtg caacgctttt cttccctaat ttaataccat
   614821 cgcctatata aacatcaaac aagataacat taataaaata ttgctgctgc atactcttaa
   614881 tactttgaat taatttagct acaggtacaa cctcatcgag tactaaagca atgtcacgtc
   614941 tagattgttg atatgatgaa aatgctttat atttaacgat attacgtgat tttatactag
   615001 ctaaattaat ttcaaataaa taacaatcag gtaatgataa ctgtttttga accatcggtg
   615061 ataatgcacc tatccaacct acttgctcat cgtttaatat aatttgagct gtttgtcctt
   615121 tttgcaaagc tgcatgttgt cctgattcaa aataaaattc agaacctgtt aacactaata
   615181 gtgattccaa atcagcctta atatcaaaaa aatctaagga ttgtaaattt gctgcccact
   615241 gtgcagaaaa acgattacct gtcacaatag cggctaactt attagattgt tcatctacct
   615301 caataccatc aaaacataaa ccaatttcaa aaaacctagc atctgtatgc ttacgccttt
   615361 gattagattc tactgtttgt aacaaacctg gtataagcga tgagcgcatg attgacatat
   615421 caattgatat tggatttgaa agtctaattt ttcttgcgtc tgggctgatt aaattctgat
   615481 atttttcaga aataaaacta taagtaataa tttcttgata accacgatta accaagcttt
   615541 gagtgatatt atattgatta atatcagttt ctgaagtaga attaatattg gcttctaaag
   615601 acaatttttg tacaggtaat ttatcataac catagagcct tgccaattct tcaattaaat
   615661 cagcaggaat acgaatatca aatctaaagc ttggtgggat aatagtccat gaattattgg
   615721 tttgttgtga tatttcaaac ccaagattgg taaatttttg ctcaatccat tttgcgtcta
   615781 attcaagacc taaaatcttt ttaattttct cttgattgat ggtgattggt tttagttgtg
   615841 gtaatgcact tttgtcaata caggcgctaa ttttacttgc ttgaccacca caaattttca
   615901 caatgagttg tgtagcacga tccattgcca actcggtcat attaaaatcc acgccacgct
   615961 caaaacgtag agatgaatca gtatgtaagc cataacttct agcatttcct gaaatagata
   616021 ctaattcaaa aaaagcgctt tctaataata tattagtaga attattttga gcagaacttg
   616081 acatgttacc cataacccct gcaatagaaa gcactaaatt actatcagca acaactaaaa
   616141 tatcttcctt taactttatc gtagttccgt tcaatagttc aatatgttca tcacatttgg
   616201 ccattctaac ttcaatatta ccttttaact ttgataaatc aaacacatgc attggttgac
   616261 ctaattctaa taaaacaaag tttaaaatat ccaccacagg tgtatgaagt tgttgaccag
   616321 aatatactaa tttatcagcc atccacttag gtgttttaac tgtgttatcg atatttttaa
   616381 tacttcttgt taaatacttt gggcaggctt tcgtatcaac aacattagta ctaataacac
   616441 aatcaccttg tgcaagcact tcaaatactg gcaaattaaa agccaaatta taattagcac
   616501 tcacttcacg ggcaatacct aaaactgaaa aacaatcacc acgattaggt gtaatgttta
   616561 attcaattat ataattatca aagtttaaat gctccctaat atcttttcca ataggtgtat
   616621 tggcttcaag ctcaacaata ccttgtgata agtcagacat acctaattca gattctgagc
   616681 aaattatacc aaatgactta acacctcgaa aattgactat tttaatctct aaaccattta
   616741 gcaactgaga accaaccata gcaacaacca cttttaaccc tgaacgaata tttttagcac
   616801 cgcaaataat ttgtaaattt ttttcttcac ccacatctac ttgacacaaa tttaatttat
   616861 cagcataagg atgtttatta taagatacaa catgacctac caccacaaca cctttaaaag
   616921 ctggcataat agatgtaata ctatcgacct caagccctac catggttaaa tgctctacta
   616981 atattctatt agttacgttt ggatttaccc actcacgcaa ccaatttgat aaaatattca
   617041 tctaaactgc ctcaaaaaac gattatcatt ttcaaaaaaa aggcgcaaat cattcacact
   617101 ataacgcaac attgacaaac gttcgattcc tatcccaaat gctaacccag tataaacctc
   617161 tgagtcaata ttaactgatg acaacacatt aggatgaaca acaccacacc ctaatacttc
   617221 aagccaaccc gtttttttac agactcgaca accttttcca gaacacataa cacattcaat
   617281 atcagcctct gcagacggct cagtgaatgg aaaatatgaa ggacgaaaac gtacttttaa
   617341 tacttctttt tcaaagaaag tacgtaataa atcaatcaat aaacccttaa gttgcgcaaa
   617401 atttgcatat ttatcaacaa ttaaaccttc aatttgatga aacatcgggg tatgtgtaat
   617461 gtctgaatca aaacgataaa cccgaccaga tgtaataata cgcactggtg ggttttgttt
   617521 ttctagtgta cgaatttgca caggtgaggt gtgagtcctt aataacgttt ttttatcaat
   617581 ataaaacgta tcatgcatgg tacgagctgg atgatgttta ggaatgttaa gtgcggtaaa
   617641 attatgaaaa tcatcttcta tttcaggacc cataactatt tcaaatccat tttttacaaa
   617701 tagagactga atgcgattaa gcgttattgt gattggatgt agaccaccca tttcagcgtg
   617761 tctacctggc aaagaaacgt caattttttc tgctaataag cgtttttcta atacaacaaa
   617821 ttctagataa ttttttttat cagttaataa catttgtatg ttaactttaa cctgatttat
   617881 agcctctccc attttaggac gttgctcttt tgaaagcttt cccaggtttt ttaacaaaaa
   617941 agttaactca ccttttttac ctaaaaaact aactcttaaa tcttcaagct cttgtaagtt
   618001 ctttattttt tcaatagagg ttttggctct atcaagaata gtatctatca aatcactaac
   618061 caaattattg acgtatcaag tgcactattt atctaccagt tgaattttct tcaaatagtc
   618121 catatctaat acactaacag tagatacttt atctctctca tcacactgca tttaccacaa
   618181 taacaacata taaagttata tcaacaacag tcccctagat tgataatctg ataatttaat
   618241 agccttacta aaaataatac accatactgc cagcatacta gataattgat cagtttcaac
   618301 ataagaatac tcatttttac ctttttatct ttagttaatc gataactgac aagacgataa
   618361 aataaaacaa ataatactat tcataatata ttctatatct agctcctatt gttatattaa
   618421 tattatacag ataaagcttg ttttacttgg tctacaatct ttgcaaatgc tactttatca
   618481 aagatagcaa tatctgataa aaccttacga tcaatttcaa ttcctgcctt actcatgcca
   618541 ttaatcattc ttgaataact taaaccatta ttacgcgctt cagcattaat acgcacaatc
   618601 caaagtctgc gaaattgacg acgtctttga cgacgatccc gatatgcata ttgccctgct
   618661 ttaataatag cctgtttagc aatacgatac accttggaac gagcgccata ataaccctta
   618721 gctttcttta aaattttttt atgtttagcg tgcgcttgca cacctcttga tactcttgcc
   618781 attttttata ctctttaact atacggtaac attttacgaa ccatcggaat atctactttc
   618841 tcaatagagt ctggtgcgcg taaactacgt tttctagaag tactcttttt agtcaaaata
   618901 tgacgtaaat gagagtgttt acatttataa ccaccactgg cagttttttt gaagcgcttt
   618961 gcagcgcctt tattagtttt taacttcggc attatttact ccttttttag ccctatcaag
   619021 cttttgtatt ttcagacttt ttagccttac tttttctttg atttaggtgc cagcatcatg
   619081 ccaagctgac gaccttccat ttttgccttt tgttcaacat tagcaaaatc ttctgtatct
   619141 ttctctattc tatctagcat tttcatgcct aattccttat gttgcatttc acgaccacga
   619201 aaccaaatac caactttaac tttatctcca ttatctagaa acttgactaa atttctaaat
   619261 ttaatttgat aatcactctc ttccgtacct ggacgatatt taatagtttt aactgtattc
   619321 ctcttttgtt tctttttagc ttctttcttt tgttgcttta atccataaag aaacttacca
   619381 aaatccataa ttttacaaac aggcggttgt gcactaggag aaacttctac taaatctaac
   619441 tcagattgaa ttgcttcttg cttcgcaata tcagtattaa caataccaat ctgcacgcct
   619501 ttagcgtcaa ttaatcgaac ttttgttacc ctaatggcgt cattaattcg agtttttact
   619561 ttatttggtt ttttaataat gtctcctggt ttactttttt tataaacgtt ccaacgctca
   619621 ttgcacctaa atcttttcca ccacgttgcc gtactgaaac ttgacctttc tccatttcac
   619681 gatcacctac cactaaaata taaggataac gttgtagtga atgctcgcgt attttaaagc
   619741 ttaccttctc atttcgcaag tctgaaatga ctctaagtcc ttgttttttt aactttttaa
   619801 caatatctac aataaatttt gcgtgttttt cagaaatatt aataataacc gcctgaatag
   619861 gtgataacca acaagggtac gcaccctcat aatgttcaat taaaatacct aaaaatcgtt
   619921 ccaatgaacc cataatggca cgatgcaata tgacgggagt tttctttaca ctattctcat
   619981 caataaattg tgcacctaaa cgttttggca tagaaaaatc aacctgtaaa gtgccacatt
   620041 gccactgtct atctaaacaa tcttttaata taaattcaat tttaggaccg taaaatgcac
   620101 cttcaccttc ttgtaactcc catactatat tcttagcatt caacgcttct accaatgcta
   620161 tctcagattt atcccatact tcatcagaac caacccgctt tttaggtcga gtagataact
   620221 tgatattaat cttttcaaat ccaaagtatt tatatacatt aaatgttaaa tcaataaaag
   620281 ttgaaacctc atcttgaatt tgttcaggtg tacaaaaaat atgaccatca tcttgtacaa
   620341 aattacgcac acgcataata ccatgtaatg tacctgaggg ctcattacga tggcatgaac
   620401 caaactctgc tagacgtaac ggtaaattac gataagactt taaaccttga ttataaattt
   620461 gaatatgtgc aggacaattc ataggtttca ctgcataatc acgatcacca ctagtagtgg
   620521 taaacataac atcaccaaat ttatcccaat gacctgactt ttcccaaaga cttttatcaa
   620581 ttaattgggg ggtatgtacc tcttgataac cattatctct gaaaataccg cgcatatatt
   620641 gttcaactaa ttggtataag atccaaccct tggcatgcca aaaaaccata ccaggcgtct
   620701 cttcttgtat gtggaacaaa tcctgagttt ttccaatttt acgatgatct cgtctcgcaa
   620761 cttcttctaa cttatgtaaa tatactttta aatcttgctc attcccccaa gccgtaccat
   620821 acacacgctg taacatttca ttactagaat caccacgcca ataagcacca gccaatttca
   620881 tcaacttaaa attcttaagt ttagcagttg aaggtacatg cggcccacga caaaggtcaa
   620941 taaaatcgcc ttgcttatac aaagatagta tttgatcagt agaaattgac tcaataattt
   621001 taaccttgta atattcgccc ttatctttaa aaaactgtaa tgtctcatca cgactcattt
   621061 caaatttttc aatcttaaga ttttgcttaa ccaatttatg catatttttt tcaattttaa
   621121 ttaaatcacc ttctaaaaag ccatttttat aagcaaaatc ataataaaaa ccattgtcaa
   621181 ttacaggacc aatcgtcacc tgtgcatctg gatacagcat ctgagtagct tgtgccaata
   621241 agtgcgctgt agaatggcga ataatctcaa gcccttgatc atcatttgcc gtaataatcg
   621301 taagattagc atctgtctta attaaaaacg aagtactaac caattcacca tcaacctcac
   621361 cagctaatgc agctttaacc aaacccatag actttgccac ttgctcaaca ctaactactt
   621421 gttcaaatat tttttttgtt ccatctggca gagtaataat tggcattaca gaatattaaa
   621481 tctaaaaaag aaaaaactaa attttacctt gataatacta ttattttaag gcctttattt
   621541 gtacaattat tagttgtaat gaagtactac ctctccaact attaatagac aatttataaa
   621601 ccgccaaaac ttgcacaaac tcaagtagcg gttgaaagaa tgcaatacca tcaaatactt
   621661 tggtattacc cttaaatttt aagcgacatt ttagatgttt tttaccaacc actttttgct
   621721 caataatctc aaatttacca taaaaaatag gctcgtcaaa tccttgaccc caaggtccaa
   621781 catcaactaa taattgtgca ttgtttaagg ataattcaaa tacctctaat tcaccatcag
   621841 ttaacaaatt aactttagat atttggttat ctagatgaat ttgaatagcg tctgaaaaaa
   621901 cttgtttaaa attagaaaaa ttttcagatt tgatacttaa tcctgctgcc atagcatggc
   621961 cgccaaattt tacaattaaa tcagggtttt gcctatctac taaatctaat aaatctttga
   622021 catgtacact gggaatagaa cgaatagaac cttttaaata attacctgac tgagcaaata
   622081 tcgcaactgg acaatgatag ctttctttaa gtttaccagc cacaataccc acaataccct
   622141 catgccaaga tggttcaaat aaactaatag caaatctatc atgacccata tctttttgtg
   622201 taaaagataa ttcttgcata tcaacaatag cttgtgcttg atcttgcata cgggcttgtt
   622261 cttgtttgcg ctgttgatta aacctttcta actcttgagc gtaacgccta gcatcattta
   622321 tatcatcagt taataagcaa cgtatgccac atgcaatatc acttaaacgc cctgctgcat
   622381 ttaaacgtgg agctatagag aaagctaaat cacttgcaca taaggttgaa cttggtcgac
   622441 ttgagatttc taataacgcc aaaatacctg gagaacattt ttgttgttga atgcgtttaa
   622501 taccctgatc aactaaaatt ctattatttt gatcaaattt taccacatca gccactgtac
   622561 caagtgcaac taaatctaat acatttcgta agtctggggg aacaattttt tgatggataa
   622621 aataatcact ctcactcaaa taagttttta aagcagaaaa tagataaaaa caaaccccaa
   622681 cacctgctaa atttttgctt aaaaattcac aatctttaag atttggatta ataattgcat
   622741 ctgcattagg aagattctca ttgggtaagt gatgatcagt tacaataacc ataatacctg
   622801 ataattttgc taattttatc ccatcaaaac ttgaaatacc attatcaact gtaataatca
   622861 aatcaggctg tttttcttga atagctaagc taacaatttc ttcactcaaa ccataaccat
   622921 gttcaaaacg attaggaact aaaaaatcca catattttgc ccccatcatg cgcaatgact
   622981 taactgccac aacagacgca gttgcaccat cacaatcaaa atcaccaaca atcaaaatac
   623041 gtttttgatt aagtaaggct tgctcaagta agacaagtgc gatatctagt tgaagaaaat
   623101 taggctttaa tagacgacta agattcaaag acaaatgcga ctcattaatt ccacgagctg
   623161 cataaatttt ctttaaaaaa ataggaatat catctgaata tgaatcaaat aaattttgat
   623221 ctattgttct aataagcatt actaactgct cgaatatagg catcaaagga tttatcagaa
   623281 cttttactac caccataaaa aaatggcaca tcaattgcga tgttggtatc ttgttcgtcc
   623341 gcactccagt aggatttacg tttggtattc gggaaaaaaa gtagattaat aagcaaatca
   623401 ttatcaccat aaagtaataa ggttcttaat tctgactcac taggtaaccg ccaagtattt
   623461 tgtttacata acttaactat atttagtgcg ttaatatatg cctgagtatt gcaatttttg
   623521 ccccagtgac aatggtgact atagtcacca ttgctaaccc ctgattgacc atcaaaccaa
   623581 gtgtaactac tatttgcatc ttgtaatcct ttatcgttta atttaacctc ccatactaac
   623641 ttggactgtt gatcaagtac acatcgatga tctttaacct cacttttaag aatgttttct
   623701 cgttctgaaa ccttaattaa ctgtgcatta ataatcaatg cataaataaa taatactaaa
   623761 aagacaatta ttttatgcat tgataatcaa ctgtttaatt cgatctgaac tagcaggtgc
   623821 catattcaaa ccattacaaa aatgtccagt atttatgaat aaatgttcaa attgttcatg
   623881 tctacctaat atgaccttac cagaaaggct tgctggtcga aaaccagacc aatgatgttc
   623941 aattttcaca ttaaataaag atggaaatct ttggtaagca aatttatgaa gtgatttttg
   624001 aacgccaata tcggtatgat tatcaaaacc aacattttcc atggtagaac ctactaatac
   624061 tctcccatcc tcccttggaa taatatatct accttgatct aatacaatat tttttaccat
   624121 actttttgta gatttaagaa taatcatttg tcctttcatt ggaaaaactt catcaacaag
   624181 ttttaaccat tttgaactcc atgcgccaga gcaaacaata acatcttgtg caaaataatt
   624241 tttatcttta gttcttacgc caatcacttt attgtttttt atcaataaat tattcacctt
   624301 aacatactcg atgatatcca cccctttatt taaaatatca acctttaatg cttgtaacaa
   624361 cctcggatta cgaacttgag caatattaga aaacagtgca ccatcaacat gaaattgata
   624421 atcaacatga tatctattca tccattctat tgctaatggc aagtcatatt catccatcat
   624481 taacaagcca gattgaatat attgcggatc aatacccgta tcttcaaaaa tttgtaaaca
   624541 tagatcttca taaattattt gtgaagcaaa acttaattca ttggttaaat catcataacg
   624601 ccaaggatac aatggactaa taataccccc acctgcccaa gatgactctt taccacattc
   624661 acgttgatct aacaaagtaa cactaacacc ttccattatc aatgtccttg cgctcatcat
   624721 gccaataata cctccgccaa ttaccaaaca atcagtcatt ttccccaatc cactattatc
   624781 aatactacca caccaacact gataaaaata tcagcaaaat taaaaattgg ataattaaat
   624841 ccactgtaat gaaaatcaat aaaatcaaca acaaatccat tagtaattcg atcaatcata
   624901 ttaccaattg cacctgataa aatcaatact agactgataa gtttaaactt atatctcaaa
   624961 ggtgttctta gaatccaaat actaataata acactagaaa ttgcagaaat acctgataaa
   625021 aaataacgtt gccaaccact attatcagcc aaaaaactaa atgctgcacc ataattatgg
   625081 gaaaaagtta acgataaaaa ttcattaatg ataattgaat tatcaatacc taaatattca
   625141 taagctaata attttgttaa ttggtcacaa acaactaata acacaactag taaaaaataa
   625201 tgtcttactt tcatcttgaa tttagattaa attttaatat aaaaataatg agtattacaa
   625261 accccaaacc aataacaacc caaaacaaac taccaaattt tgtataacct gataaaacct
   625321 taataattac aagttcagtt aactcaaatg ctgacatgtg caaagtatct tttacctaaa
   625381 attttcggca atggaaataa aaacactgct accataagaa aaataaatag gaaatagaga
   625441 aatagagcta attctaaacg ttcgaataga tgttaagaaa acatataaca tataacaata
   625501 gtaaaaatag ttagttatta taagtgttgt ataggttata atttgctttt tgttaaaaac
   625561 aaaattatag atctatgggt ttcttaactg gtaaaaaagc acttattgtt ggtgttgcat
   625621 caaatcgctc tattgcttgg ggaattgcac aagctatggc taaacaagac tgtgagattg
   625681 cactcactta tcaaaatgat aaacttaaaa aacgggttaa taaatgtgca gtaatttgtc
   625741 actcaaatat tgttattaag tgtaatgttg ctagtgacaa ggacattaaa aaaactttta
   625801 aagaattaaa aaactattgg gataattttg atattattat ccattcagtt gcttttgcac
   625861 cacgcgaagc gctaaatggt aactatatcc aagcaaccac tcgtgaaaat tttgctacaa
   625921 cacatgatat tagttcatac agctttactg cgctcgccaa atatgcatcc tccatgctta
   625981 atgataatgg agcattatta acagttagtt atttaggcag tattcgatct atcccaaatt
   626041 ataatgtgat gggagtggct aaggcttctc ttgaggctaa tgttcgttat atggcaacag
   626101 ctttaggacc tgaaagagga attcgcgtta atgcggtctc atcaggccca attaaaactt
   626161 tagcagcatc tggtatcaaa aactttggca agctacttga ttattctgca gatagttctg
   626221 cactcaaacg caacgtaacc attgaagatg taggcaatgc tgctgcattt ttatgttctg
   626281 atttagcctc aggcatcact ggtgaaatca cttatgttga ttctggctat aatttctatg
   626341 acaagggtcc gaattaacaa tatttagcaa acaagctagc ttcttataat agtgtatctt
   626401 tataaatata tgaaagtctc acattattaa tacacttaat caatagtttg ttatgtcctg
   626461 taaataataa aatagttata gcattatgta aaataataaa attctaatta cccctaaaaa
   626521 atatcatctt aatatcttta ttgagtattt aaaccatttg atcttatctg tctttttaca
   626581 aaagaaagct tagtccaata tctccctctt atcttcttaa attaacctat ggaatttaat
   626641 gttgcctaac tctcattttt ctattaaaaa tagttgctat attataattt caaaatgaag
   626701 aatctaatta gattaactga ctgaatatca gataagttaa attacaagtt tctactaaaa
   626761 attttaattt ctgcttgaga tttaagcatt tcaagaatat ttgaaaatac ctcatttgac
   626821 tcaaaactta gcaaagattt ttcaagtaca gcgttgacta ttttaatatc tgtcgtttta
   626881 acacctaata gatcaatcac aattgcatta cccctttcta aattttgagc actgtagcta
   626941 gatttactat taattggttt agccaatgca aacactttat tgacaatagt agttttaact
   627001 ttattagaat ctcgttttat ccaacccaca cgatgccatt ttagtttatt tttaatcatt
   627061 attttttcaa gtgtatcttt atcattatga accaataaat caacaatatt cttagctaaa
   627121 ttatcaacaa aagttttagc taatagtgtc attaaatgtg tattaatttc acttttaact
   627181 tcagaaaaag atttttgtct ttttactaat ttttctcgta cgcgaataac cattaattta
   627241 tcttttgata attctaaaac ctctgaattt tcacctttat taagaaccat atcactaaat
   627301 gcagtggtta caattttttg gtttaattgg gtgttacgtt tatcaaaaaa atcactcact
   627361 tgaagcttta aatccatttg atcaacaatt ttctctaaac ttgtctcata ggctaagctg
   627421 gctaactgtt cagttaagtt ataaaatact ttttgtgctt gtttttgaat atataaatca
   627481 agtatttcct gtttagctat atcaaaagat ttaagagtct taactttaat attatttagt
   627541 ttaataatat gatagccaaa tttagattta actaaatcac tcacctcccc agatttcata
   627601 gcaaacactt ttttctcaaa ttctggcacc ataatacccc gagtaaaaaa acctaaattt
   627661 cctgcatcgt ctttagaacc tgaatcttga gaatattgct tagcgagctt gacaaaatca
   627721 ccaccattat ctaataatgt aacaactttt tgtgcggtta attcgtctgt aagcaaaata
   627781 tgctgtgctt gcctttcttc ttctgtagta aaattttctt gctcattttc ataaaaatta
   627841 aataattcgt tatcacttac tttaattttt tttgcaattt cattcaatga caattcaata
   627901 aattctattt ttacttgttc tggtgcaaaa aataacgact ttttattatc ataaaaatct
   627961 ttaacacttt gcgcatcaac cttaacttct ttaatatgat tatcagtctg aataataata
   628021 taactaaatt ttcgtttttg atcgttcaat ttttgtaatc ttaaaagttg tgatggtgta
   628081 ataaaagcag aatctaatag gttagattta atttgagttc gccttaattc ttgtaacttt
   628141 attgtctcat atttttccgt tgtatagcca ttaagcctta ataatttctt atatttttct
   628201 aatgaaaatc gtccttcttc tttaaacaaa tcattagctc gaataatatt gttaagctca
   628261 ctggtagttg tttcataaga taattttcta gacaactgct caagcaaatg tttattaagc
   628321 atttgattaa gaatagattg ctttaatata aaatcaaatt ttttatcata ttttttatct
   628381 aattcttttt gtaaccatct tttttggggg ttaaattctg aaagaaattc ttcttttgaa
   628441 atatcaacac catcaaaaga agcaacttta atatttgaag caccagtaaa atattcactt
   628501 ataccaaata aagcaaaagg gataataatt aaaccaataa ttaagtagga tatccaaccc
   628561 ttggttttgt ttctaattga aactagcata atagtatgta ttaacggcta ataattaata
   628621 atctaagaac cgtttatttt taataaaaat aagaattata aacgaaaacc tttgtattaa
   628681 tacgtaggtt ttattatgct ttaaaaattg aattttgaat gaatcaaaaa acataataaa
   628741 gaaaaaatta tggcggagcg gacgggattc gaacccgcga catcctgcgt gacaggcagg
   628801 cactctaacc aactgagcta ccgctccgaa tttatttttg gtgggcgcta caagacttga
   628861 acttgtgacc ctcgccttgt aagggcgatg ctctaccaac tgagctaagc gcccaaaaaa
   628921 aatacctagt attatatagc aaagaatcag gcatattata ctttaagaat taactgattc
   628981 tttaagtaat ttacctgctt taaatgcagg cactttagaa gccttaattt ggattgcttc
   629041 gcctgtttga gggttacggc ctgtgcgtgc tgcacggtca cgaacaacaa aactaccaaa
   629101 acctgtaata gccacattat caccacttgt taatgctgag gtaattgcac ctgtcatggc
   629161 gtccaatgca cgagctgaat ctgcttttgt taaattggaa atttgtgaaa ttactgcaac
   629221 taaatctgat ttattcattg actttattct cctgtatgta aacctttttc gattaaaaaa
   629281 tatcaaactt gaaattaaac tttagttgaa ttatccatta aatatcagtg ctgtcaatgg
   629341 actttgataa aaaatatact aaattttatc tcatactatt tcttaactcg tcaataagag
   629401 gagaaatttt actttcccaa attcgtggag ttaattcacc aatacgctta aaacgaataa
   629461 taccttgctg gtcagtgata aaagtttcag gtgttgcata tacacctaac tcaaggccaa
   629521 gcttgcctaa ttgatcaaat acaatcgaat catacggatt accaagtcta gttaaaaata
   629581 tatttccatc ttttctggtg tctttataat tgattcctaa tatttgtaat gagttggttt
   629641 tagctatttt cattaatatt tcatgctcaa ctctacaggt aacgcaccaa gaagcccaaa
   629701 cattaaccaa agatattttt ccctgtagtt tatcttgaat agcgtaaatt ttagcactat
   629761 tgaaatcttc tacttgtaaa tttggaaacg ctctaccaag taatggtgaa ggtagttttg
   629821 taggatcaag tccaagacct atatataaaa aacttgctag tacaaaaaat aaaattaaag
   629881 gtagaaattt tttcattgtt tatttttagc tttttccaac gcatcagcca cttctggtgg
   629941 catatagttt tcatcatgtt tagcaagtac ctcagttgcc atgaaaacgc catcaactaa
   630001 agaaccggtt gtaataacgc cctgaccttc tttaaataaa tcaggcaaaa ttcctgaata
   630061 attgacacga aaagtgttag aataatcagt tacatcaaat acaactttaa tgccatcatg
   630121 tttaatgcta tccttaacaa tcataccacc taaacgaaaa tctttatctt tgggagctct
   630181 acccttagtt acatcagtag gagataaaaa atacaataaa ttctcgttaa atgcttttaa
   630241 acctaaataa cccgctaaac tcacacctat taccaataaa gcaactagta ccattctatt
   630301 ttgtcgtttt gtcatgttat ttttctctta aatacttaat gcgtaattgc tcgattacat
   630361 ttttgtgaat agaatatgtg cgtataaata aagttgcaat tacaatcaaa gtcattaaat
   630421 aagaaaacca aatataaaaa gcgtactttc catacggaag aaaagaaaaa tattctgcta
   630481 acgtcactat ctatgctcca taattattct tttaacccaa ctagagtttt gttctatgac
   630541 caacacttca tctctagccc tcattaacat aagcgcacca tataaaaact taaatgccat
   630601 acccattaat aataatgcaa tcaacatatc aacatcttgg atggctactt tattaacact
   630661 aactgacgca ctctgatgta atgtattcca ccatttaacc gaataatgaa taataggtaa
   630721 attaaccaaa cccataatag ctaatactga agaagccttg gatgcagttt taggattatc
   630781 aaatgcatta ttaagtgaca tataagctaa gtataaaaac agtaaaatta actctgaggt
   630841 taaacgtgca tcccacaccc accaagtacc ccacattggc ttaccccaaa ccgcaccagt
   630901 agttaaggct aaaaaggtaa atgctacccc aataggcgct gacaccttag caatcacata
   630961 tgctaattta attttccaaa ttaggccaat accccctgaa attgctaaca ccaaataaac
   631021 aaacatactc atccatgcag caggtacatg aataaacata atgcgataac tctcaccttg
   631081 ttgataatca ataggtgcta caattagtcc ccaatacaaa ccgatcaaca ttagaataat
   631141 aaaagggatt aaaagccaaa gaataatttt ttgactaatt tgatagaaat ttttaggcga
   631201 ggcaaaagtt tgaatccatt tccacataaa ccaatcctgc tagttattta gcttaataaa
   631261 atatattatt ttagcgattt atgtgcaaca ttattacgta aataagttgg cagtgccaac
   631321 ttattgctaa atttaatatg ttggttaaca caggttaaat aaagtactat aagattctca
   631381 gcttttggat aaaaattggc aaaacaggta ttaatacctg tttgttgaat gagctcatta
   631441 tcatatacac cccatccatt tcccacacca ataaaatatt tcccaagaat atccacttca
   631501 tcaggctttt gtaaactttc cttacacagg atttgatttt gataaatacc ccaatatacc
   631561 tcactcatac gtgcatcaag tgcaatagca actttgctag tattgtactt tttaaacgct
   631621 ccaaacccaa gtaactcaag tgttgaaaaa cctaatgtag ggatattata cgctaacgat
   631681 ataccttgaa ctacactaac acacattcta acacctgtaa aagatccagg gcctttagtg
   631741 taaataatac catccaaggc agaaggtgac atttgactag ctttaaaaat ttcatcgcaa
   631801 agtgataata ttaaacctga acttttcttc tcgctttgaa caaaacgaga aaaggtttca
   631861 ccttgagtgt aaagacttac cgagcacgta ttagtacacg tatcaattgc taataaattt
   631921 atcatttttt taaacttata atagattaaa caaattattt gtatttaaac agtttaataa
   631981 atacctagct gagtgataat aatcagagct tttaactaaa actacaagct ttaaaatttt
   632041 tttaagttat aattatatca ttcaacatta tcttttttaa agaaaaacca aggtaaaatc
   632101 attaatactc ttattacttt tttaactaaa atacaaaata tttatataac tattaagcat
   632161 gcattctttg attgaataaa tatagcaata ataacttcat caatgtttct ttgacttttt
   632221 attttaaaac ttctctttct ttaataagat atttttaatt agatacatcc ttattgatat
   632281 tagttccaag aaatgacttg ttatttaaaa tatgtattat aataaattat ctgaatttta
   632341 acaaaagcta tacacaaaat attttttata caatatatag agttaagtga ttgttaaaaa
   632401 caaataatta gtataaaatt ctttcttcct tgcttgagag cactattttc caagctatta
   632461 aaacaataac cataaggaga aaactcatga gacattatga gattacactt attgtccatc
   632521 ctgaccaatc agctcaggta ggtacaatga tggacaaata caaagaaatc atcaatgctg
   632581 atggtggtaa gattcataaa gaagaggatt gggggcgtaa gcatttagcc tatccaatca
   632641 agaaaattta taaagcacat tacttaatga tgaatattga gtgcgaccaa gagatgcttg
   632701 ataaactcaa ttataatttt cgctttaatg atgctattct tagaagttta atcatttcta
   632761 agaataaggc aattaccaca ccatcaatca tgatggttaa taaagataaa gaaaaaggga
   632821 aatcataatg gccaagcaaa taaaaagaaa acgtagacct caaattaaaa ttaacacttt
   632881 ttgccgtttt acagcagcag gagttacaaa aattgattat aaggatattg acatattact
   632941 taaaaatatt gatgaaagtg gaaaaattac accatcaaga atgacgggta ccagtgctaa
   633001 atttcagcgt aaactaacaa ctgccattaa aagagctagg ttcttagctc ttattcctta
   633061 tactgacaaa cacaagaaat aggagtctat catgcaagta attttattag aaaatatcca
   633121 aaaattagga aacttaggtg atataatcaa cgttaaagct ggttatactc gtaacttttt
   633181 aattcctaaa ggtaaagcta aacttgcaac taaaacaaac ttagttgaat ttgagttgat
   633241 tagagctaaa ctacaaattg ccgaagctaa aacacttaaa aatgcaaaag cgattgaaac
   633301 taagatgact aatactattt gtattatcca agctaatgca agtgaagaag gtaaattatt
   633361 tggctccatc aacaccactg atattcaaac aagtcttata aaaagtggtt ttaaaattga
   633421 aaaacgtaat attgatatac ctgaaacaat tcgtcataca ggtgaatata aaattaacat
   633481 taatttacat acaaatatta cagtaagtgt taaaattgtt attgaagctc ttcaaaaagt
   633541 ataaaaaact aattcattgt acgttaaaat taaaaaccct ataatgaggg tttttaattt
   633601 tttaaaaggt tctttaaaaa gaaaagccaa tgaatatcaa aaacaccaaa ataccaccta
   633661 attcaattga atcagaacaa tctgttttag gtggtttatt gttacataat gaagcgtggg
   633721 atcgtgttgc agatatttta actcaggtag acttttacaa cgcctcacat aaaattattt
   633781 ttaatgctat tagcactcta ttgcagcacg accagcctgc ggatattctc actgtaaaag
   633841 aacaagtaaa aaaaacagat tctgaagaaa ttattggtgg ctttttctat ttagcccaaa
   633901 ttgctgaaaa tacccctagt atttctaaca ttgaagctta cgctaaacat gtgcgagaat
   633961 tatcagttta tcgtcaacta attattgtta gtcaccaaat tgctgatgct gcataccatc
   634021 caaaagaagt tgaagttcaa gaattaattg atctttctga gaaaaaaata tttgaaattg
   634081 ccgaacaaat gactcgtgga aaacaagata ttactaatat aaaggatatt attaaagatg
   634141 ttgttaatcg catacaagaa atgcaagaat atagcggtat aaatggctta gagactggct
   634201 ttattgaatt agataagtta acttctggct tacaaaatgg cgatctaatt attattgccg
   634261 ggcgtccatc tatgggtaaa acagcttttt caatgaatat tattgaacat attgctatta
   634321 ctgctaaaga acccaaacca gttgtaatat ttagtttaga aatgccaact gaacaattag
   634381 taatgcgtat gatttcatca tttggtcata ttgaaggctc aaaattacgc aacaccatga
   634441 ctgaaactga ctggaatagt tttaaccatg ctgtattagc tctggaaaaa tctaccgttc
   634501 ttattgacga aaccccttct attacaccaa tagaaattcg cgcaaaatgt cgacgattaa
   634561 aacgtcaata cccgaactta gcattaatta tggtagacta cttgcaactc atgactgtac
   634621 acggaaagaa tgaaaataga gtgcaagaaa tttctgaaat ttcccgttca ctaaaagcac
   634681 tagctaaaga aattaacgta ccagttcttg ccttatcaca acttaatcga ggagttgaat
   634741 cacgccttaa agctaacaaa ggtcgtatgc cacaaatggt tgatttacga gaatctggct
   634801 cgattgaaca agatgctgat attattggct ttatctatcg agaccaacaa tatcatgatg
   634861 atacctattc aaacccagaa gaaattggta aggcagattt aaagattgtc aaacatagaa
   634921 atggacccac tgggataatc aaacttgcct ttatcggaga atatgcacga tttgaagact
   634981 tagctaacga ggaccaattc cacggtatga acgatgaaca aatagataca acttatgcac
   635041 ataatatagc taattttgac caggaacctt tttaataaaa accttgtcta tgtgtaccat
   635101 tgtttcaatt tcacaatcag cattaaaaca caatctctta gttgtaaaag aaaattcgcc
   635161 taattccaaa atagtctcta tggtaaaggc aaatgcttat ggtcacaaaa ttaatttaat
   635221 aaatccaatt attaaccatt ctgatttatt agctgtcagc gaaatctcgg aagcaaaaaa
   635281 attacgtaaa ataacaaaaa aaccaatttt gcttctatca ggtgttattg aagaccaaga
   635341 actacaacaa gccattaaat taaattgcca aattgttgta catgataaaa cccaaattac
   635401 cactatcaac aataccaaac aaccaatcaa tatttggata aaaattaaca caggcatgca
   635461 ccgattaggc ttgtctaccc atgagtactt tgattgcata aaattattag caaacaaccc
   635521 attaattaat acccaatgtg ttatgagcca ttttgcttgc gctgatgaaa ttaaccaccc
   635581 aatgaaccaa tctcaactat ttgaatttaa aaaatcaaca tatcacacta ctaaacgttc
   635641 aatggcaaat tctgctgcga ttttgtcaaa cccagcctca cactttgatt atgttcgtcc
   635701 tggtattatg ttatatgggg tttctccttt tgaaattatt aataatcatc ttaagcctgt
   635761 tatgcaaata tcagcaccaa ttatgtcaat taaaaccatt caaactggtg attcagttgg
   635821 ctatggcgct acttggatag ctaaaaaatc aacaaccata gcaactatcg gtatcggtta
   635881 tggtgatggc tatccacgcc atgctaaaaa tggtactcct gtactaatta ataacaattt
   635941 atgtccactt attggtcgtg tatcaatgga tttaatttgc gttgatataa gtaatgttaa
   636001 agcctctgtt ggagataatg tcattctttg gggggctcag aaattacgca ttgaaactat
   636061 tgcaaaatac agcgatacta ttgcttatga actactcaca ggtattagtt ctcgggttgc
   636121 ttttgttagt actatatgaa ctatagtctt attcagatta gcgattgtca cattgatgat
   636181 aataagtact ctatgggtgt taatacccat atcaatctaa aaaaaattat tagtagaatt
   636241 agccatatta acattgatgt actattaatt actggtgatc ttactcacaa aggctcaatc
   636301 acttcttaca aagctctaca acagatgcta taccccattc aaataaaact gttgatcata
   636361 cctggtaatc atgataacaa aaacaatctg agcgctactt tttctaaaaa tttatttagt
   636421 caattcacac ttggaaagtg ggaaattatt aatataaatt cagtgcaagt atcaaaaacc
   636481 agtggattct taacaaaaga tgaactaata aaactagagc ttaatttagc acaatcaatt
   636541 gctcaatata tactcattac attacaccac cccaccgtac caatgaatag tacttgggat
   636601 gattcattgt ctttagaaaa cccagaagca ttgtttaatg tacttgataa ataccataaa
   636661 atacaagcta tactatttgg tcatgcgcat caagcagctg aatttaaaag attaggggta
   636721 aaaattattt catgcccatc aactgcctta caatttaaca atgagactag aattggcttt
   636781 aattattaca cactatatga taatggacaa ctaacaatta atacacaatg gatatagagc
   636841 aatacttatt aacattttta tataatcaaa aaaagtcaaa aacttacatt aaagtttctc
   636901 aaatatttga attaaactat caaaaaaatt taaaatttat tcccccgtta aaaacaaatt
   636961 actcactatt gtactaataa gcataatagt taaaattaaa tacttttatc aaaaaataat
   637021 tgaattattt cttaagtaaa tatcaaggaa atcatgaaaa atactgtaaa aaaaaatcaa
   637081 gaaaaaaata aattggtcat tactatctca tcaagagcct tatttaatct tgatgaatct
   637141 cacaaaatct ttaaagaaca aggagttaaa gcttatactc aacatcaaga agaaaacgaa
   637201 aaagttattt taaaaccagg agtcggtttt tcactagtca aaaaattact agcactaaat
   637261 acctcacaaa accctattga tgttatttta ctttcacgta atagcgctga tacaagcttg
   637321 cgtattttta attctattga aaattatggc ttaaatattt caaaagcagc gtttacccgt
   637381 ggcgaaagta cacataatct tgtaggtgca tttggagcag atttattctt atcaagtaat
   637441 tatctagatg tacaaaaagc cttagaatca ggttttgcgg cagcatcaat tgtcggttct
   637501 agctcacaaa aacaacacaa aacccaatta cgaattgctt ttgatggtga tgcagttatt
   637561 ttctcagatg aatcagaacg aatttttcaa gaaaaaggct tgaaagcctt tatagaaaac
   637621 gaaaaaaatt cagccaatat tgcattaaaa gctggaccat ttaaatgctt tgtaatgtcg
   637681 ttacaaagaa tacagtcttc tttcccaacg ataaataacc caatcagaac cgccctaata
   637741 accgcacgtt ctgcaccatc acataaacgc gttattcaca ccatgcgtaa atggggtatt
   637801 cgtattgatg aatctttctt cctaggcggg ttagaaaaag gtatattttt aaaagaattt
   637861 agtgctgaca tcttttttga cgatcaacac caacactgcc aatcagcctc taaatatgta
   637921 cctacagggc atgttcctaa tagaattagc agtcaaaaaa tcatgctaga taaataatta
   637981 taacttaacc taatttacga agaaaatagc taccagaaat atccatctaa attaaaaacg
   638041 ttagtagtta aatttagtat tagtttcttt ttttaatctt cctctgcttt aatttatctt
   638101 tcagaagtag actcatgagc ttacaaagtg ttagaatgac acttttacaa atgcttaaaa
   638161 tccaagtgaa aatatatatt ttaatacttg ctattataat tttaaacgtc ttgaatcctg
   638221 tacaagctga atatatatat aataaaaatc tagatttaac agaaatacct attaaaaaag
   638281 cattatacaa accttttata gaacgatata ttttagatga acttaaacta ttgcgccaag
   638341 aacaacaaca attaaaggtt gattttgccg aaaaagtcgc aaatgcaaga ttagacgttt
   638401 ctgatagagc aatcagatat acagcagata ctaccactaa tattttctac atcattacca
   638461 ttgctgctac cttacttgta ttattaggat ggcgttcatt acaagacgtt agagataaca
   638521 ttaaaactat tacttcaaaa caagtatcag agttaacaca aaaatatgaa aaaagactaa
   638581 gtataataga agataaagct agaatacgct ctgaacaaat tatcagtaca caacaagata
   638641 ttgctaatac taacctaatt cattcattat gggtacgctc aggcattgcc aaaagtgaac
   638701 aagaaaaaat taatattttt gatgaaattt tagatctagc tccagacgat attgaagcat
   638761 taacctataa agctgatact ttattagata ttgatgaaga cacttggtca ctatctttat
   638821 ccaatcgtgc tatagaaata gatgataaat atgcactagc ttactggcaa agagcttgtg
   638881 caaaagccaa attaaaacaa catgatgatg cagtagcaga cataaaacta gccactgatt
   638941 taacagactc actaaaaaca gaggttatga atgaagttta tttcgagaac ttaaaggata
   639001 acaagaaata ccaagtttta attggtaaat ttggtaacat tgagaataat taacactcaa
   639061 tttaaaaaat ctaatattat atatttaaac caattactac ttgtaaataa taaaattaat
   639121 acatgatata taccttacaa tatcatgatt atcaatagct tatctaaaaa caagttatac
   639181 cttttctata aatttaaata tatcaactag ttgtataaat tttattccta atgaatcaat
   639241 agctaatgct aaactaaaat tgactgttag tataatactt ctttgtaaga gtagcttaaa
   639301 ttcaactata atataagact tattatatat atgacctact tttgtaataa tagtacttat
   639361 tacaacaact acaactacta taaagttgaa gataaaataa ctaatttatg tacttgttga
   639421 tactcttacc ctatcgttag caaaaccaac aacgtttaaa agataattac tattagcatc
   639481 atctagaatt ctaatatttt catatattta actgtgaatg agtatgtcca atatctttga
   639541 gtttttgtaa atatttatgc caaagcttat catgattcga agcaagttta tgtaagtgtg
   639601 accaagaata aataccgcta tcgtgtttat cactaaaaaa taaaattaca gcataatttc
   639661 ccgttggttg aatgcgcaaa atagtgacat tttctttatt aagttgcaat atttcttgtc
   639721 ctgaagcatg accaactact tcagctgaag gtgaataaac tcttaaatat tcggcactaa
   639781 gcggataatt aatcttatca aaagtaatag ttaataaagt tttttcttta tttaggctga
   639841 tgttagttgg tgtttgcatt agttatctta atatggagca tccaacaata ttttatcata
   639901 aacaaattaa ttgaacatta ataattataa gtgaacaata tcataaaata tgttgattta
   639961 ttttaaaaaa atacatgaag tttagtaacg acttcatagt agttgataat ttttctaata
   640021 acattacctt taatactagg aaaaaagcaa atttagacaa tctcagtatt ttagtattgg
   640081 ctttaatcaa ctgttaacaa ttaaagttag cagtataata ggtattaatt ttcattatgt
   640141 tatttataat gtttaacggt tcaaaaagaa gaataatgaa ataataacgt atattgtttt
   640201 attagtgata agaactaact agtagttatt actaattagt atctaaataa taatacaatg
   640261 tgtattgata tagaataacc aggctttagt cagaatatga tactccattt ctaatactca
   640321 aataaaatac acattatcag attgaatgga tatatataac aagaaagcta ataaagttaa
   640381 atgctgttat cctaatagat tatttcaata aaaaaagata ataacaataa caaaaatagt
   640441 aatactaaaa gatagataac gaacagatat aaatattcct aaatatatta gataaaccct
   640501 agtaatttca ttatataaat aaatattgta ttttgtttct tattcttcta actcttaaga
   640561 gagaaattgg taaaatctta taaacttcta atatttatca aaaaatgagt aaaaaaatcc
   640621 aagccattcg tggtatgaac gacttattgc caaaaaattc tgcactatgg ttatcgttag
   640681 aaaaaacaat ttttgattta tttattactt atgggtatca aaatattcgc acaccaatcg
   640741 ttgagaaaac agatactttt tgtcgtgcca ttggtggaga tacagatatt gttgaaaaag
   640801 aaatgtattc atggaaggag acaagtggtg agtcattaag cttaagacca gaaggcacag
   640861 cgggttgtgt acgtatgatg attgagcata atttacctag agaaagcatc caaaaagtct
   640921 tttaccaagg agcaatgttt cggcatgaac gtccgcaaaa gggacgttat cgtcagtttc
   640981 atcaagtagg acttgagata tttggtgtat ttaatgccaa agcagatgct gagcttatga
   641041 taatcatgca tgctttgtgg caaactattg gtttgaaaaa tattgtattg gagattaaca
   641101 ctttaggatc taacgaagtg aggaatgctt atagaaaaat attggttgca tattttaatc
   641161 agcataaaaa ccagctgaac gaagatgggt taaaacaatt aaaaactaac ccttttcgca
   641221 tcttggatag taaaaataaa gcaatacatt ctttaattag cgatgcacct aagttaatgg
   641281 attacttaga taaaaaatct atacagcatt ttaaacagtt taaatcttat ttagacgctt
   641341 taaatattac ttatgtaatt aatactagct tggttcgtgg gttagattat tacaaccgta
   641401 ctgtctttga gtggacaaca actgatttag gtacacaaag tacaatttgt gctggtggta
   641461 gatatgacgg tttaattgag aagatgggtg gtacgcccac accagcagtt ggtttagcaa
   641521 ttggcttaga acgtctagta ttgttattag aagcacaaaa cttaatatca actaaatcca
   641581 ctttatctat ttatttgatt gcattcggca aaaaggaaca aattaaatca atacaaatag
   641641 cgaatgtttt acatgatgaa ttacctaatg taatacttta taatgactta actttaggta
   641701 gttttaagag tcaatttgaa aaagcagata aagccaaagc taattttgca ttaatcttag
   641761 gtgaacaaga gctaaataat aatcaaatta gtatcaaacc tctgagaaat caaggaacgc
   641821 aacaaactat gaatttagaa gaagccatta aatattttaa ggaaaaccaa tgagaagttt
   641881 tattaaagta aatagaactg aagaagaaca aattaaacaa acccaacagt ggattaaaaa
   641941 aaatacacta caaattatta ttgctattac tgtgagtttg agtggtattt gggggtttaa
   642001 ttattataaa aaatatcaac attcacaaac tattaaagca cgagatattt acttaacatt
   642061 tagatctaaa cctcacaata tacaagtcta tgaacaacta aaaaataacc ataaaaatag
   642121 catctacctt gatcatgcaa tattaattct agctaaaaat gcagtcacta ataagaatta
   642181 tatacaagca cttgaatacc ttatcccatt aaataataca agtaatcctt ccattgctaa
   642241 agttattaat atgagaatag ctggcttaca tttagaaatg ggtaattata aaaaagcact
   642301 tgatgcatta aatactgttc ctaacagtac atttaacggg ttgtataatc aacttaaagg
   642361 ggatatttat ttggctaata acaacattga taatgctaaa aaacattata aattagcctt
   642421 aaatcaaatc tctaaaaatt ctgagttaca aaatttgatt aaaattaaat taagcgatct
   642481 taactaatca cctatggggt tacctattat ttgccttatt ggacgaccta atgttggtaa
   642541 atcaacgtta tttaatcgcc taagtcattc acgacaagca ttagtgtctg attttgcagg
   642601 gctgactcgc gatcgtcaat acgcaaaagt gcttttgaat gatgacacac aaacttttac
   642661 cacaattatt gacacaggtg gatttaccaa caaagtcaat ctagttgaca gcggtataca
   642721 ggatcaaata ttaagtgcac tagaagaatc agatgttatt tattttatac ttaatagccg
   642781 agatggtgtg attagtcttg atttagaaat cgcttcacat cttagaaggc ttaaaaaaaa
   642841 tattatctta gtttgtaaca aagctgaggg tttaaaccca accttaacta ccgaattctt
   642901 tgaacttgga cttggaaaac ctatacttat ttcagctgaa catggtcaag gtattgataa
   642961 tttaattaat actaccttac ctttactacc taaagtaact gttaatgagg aagtagtaga
   643021 aggcattact atagctgtac ttggtaagcc taatgtgggt aaatcaactt taattaacca
   643081 tattttaagg gagaaacgag taatagcaat tgatttacca ggcaccacac gtgatagtat
   643141 ttacattcct tttgagcgta aaggacagca atatacactt atcgacacag caggcattcg
   643201 tcgtaaaaat tcaacccatg aaaaaattga aatattttct attattaaaa ccattaatgc
   643261 tctggaaaga gctcatgttg ttattcttgt attagatgca caaactggag taactaaaca
   643321 agatgcaagc ctattaggta tgattttaga taaagataag gcactgttaa ttgttattaa
   643381 caaatgggat ggtttagatg actatcaaaa acaagaagtt aaacgcaaat tagaagttaa
   643441 actttctttt ataagttata ctagcgtaca ttatatttct gcactacatg gatctggtgt
   643501 ggataaatta tttacaccta ttaaccaatc ttatcaagat gcttgtaaac aacattcaac
   643561 ttcaatattg aataaaattt tagacaaagc caatcatggt catcaaccac cgcttgttaa
   643621 aggtagaagg ttaaaaataa aatatgtcaa tcaaactaac atatttccgc taactcttgc
   643681 ttttcatgga aatcatttac aaaatgtacc aaatgcctat gagcgttatt taaaaaaatt
   643741 ttttattaac tctttaaaac taactaatat ccctattaaa attgaatata aaagtggtaa
   643801 taaccctttt aaaaataaaa aaaatatatt aaatgctagt caaattgcta aaaaacgtcg
   643861 tctaatgaaa tttgttaaaa gaaaacatta agacactcta aacattgaac taaatactac
   643921 aattacactg ttcttattat gcttttatag cattattaaa attaccaaat aaaaataaac
   643981 cactattata gatcgtttta agagttaaca atccttaata aaaatacaac attatttact
   644041 aataatgttt tatagctctt atgtatctta tcggctagat aagatacata actaacttta
   644101 cactttttcc ttaatagcac taagtggatt gtcatacaat ctgtcttttt gaatctttac
   644161 acagttgctt gtacatacct cgctcatatt ttagaatcta catttaagtt acaacctacc
   644221 aatactgaat aaataactaa atatttattc attttccctt atttattaac tattctgtta
   644281 actttataga ctgcacttat aaacttctta tcaatttatt ttatttttca ttgtcatatt
   644341 tagcttttac atgtaccaga atagatacca cccatcatca cgatacacta ataactttcc
   644401 cttaaacaac aataaattta ctttgcatat gtacacatta aatctattgc acttgagatc
   644461 caaattttat ttcacttttt cttataatta gatcaacaaa actaatggtg ttattcactg
   644521 atataaattc cttatcaatc aattgataga cataaaatta acaatgattc acaaaataaa
   644581 ggaacggttt agtcaatatt tttataaata aattaaaaca aaataaggtt atttgcttta
   644641 ttggaagctt taataaaact ttcgaataac ggatgtccat cacgtggatt tgaagtgaat
   644701 tctggatgaa attggcaagc tacaaaccaa ggatgatctt taatttcaat catttcaact
   644761 aaagtaccat taatagatct cccagaaact atcaagccag atacctctag ttgtttaatt
   644821 aataaattat taacttcata acgatgtcta tgtctctcag taataaccaa cttgctataa
   644881 atctcttgtg aattagtacc ctcaactaaa acacattttt gtcctccaag acgcatagtg
   644941 cctcctaaat atgaatcttt atttagagag tgtttatatc catcaacatc tttccaattt
   645001 gttattaagt gaatgacagg gtaagctgtt tttttattaa attctgtact attagcatta
   645061 atcatgttcg ccatattgcg tgcgtattca atcacagcaa cctgcatacc aagacaaata
   645121 cctaaataag gcacattgtt ttcacgagca aatttaactg tagcaatttt accctcaaca
   645181 ccacgattac caaaaccacc tggtactaaa attgcactca tctcagataa acaatcagta
   645241 ccgttttctt caatttcctc agaatcaaaa taatggatat tgactttagt ctgtgtgtgt
   645301 atactagcat gaatcaaagc ttcagataaa gacttgtaag actctgtcaa atctatatat
   645361 tttcccacca tagcaatatc aacactagat ttaggatgtt gtaatctttt aatcacatta
   645421 tcccattcac acaaatcagt tggtttacaa tctaatgcta gttttttcac tactacatta
   645481 tccaaccctt gttcatgtaa agctcttggt actttataaa tcgtatcaac atctaatgat
   645541 gtaaacacag aatcttgaga aacattggta aacaatgcaa ttttagctct ctcaatatct
   645601 gacatcggat actcagatcg acaaattaat atatcaggtt gaataccaat acttcttaat
   645661 tccttaacag aatgttgagt tggcttagtt tttaattcac ctacaacttt aatataaggt
   645721 aataaggtga gatgaataaa cagaacatta tcacgaccta gttcaagact catttgccta
   645781 atagcctcca taaatggaag cgattcaata tcacctgctg ttcctccaat ttcaactaaa
   645841 gtaacatcag cccctttcgc acctatttga gttaaacgct taatttcatt cgtaatatgt
   645901 gggataactt gtacagtatc acccaaatat ttaccaagac gttcacgctc aataacattc
   645961 tcatatacac gacctgctgt aaaattattt tccttaccta attgaatacg agtaaaacgt
   646021 tcataatgtc ccaagtcaag atctgtttca gcaccatcat tagttacaaa aacctcacca
   646081 tgctgaaatg ggctcatagt accaggatca acattgatat aaggatcaag tttaagcata
   646141 gtaatattta aaccacgtga ttctaaaatt gaagctaaag atgcactaac aatacctttc
   646201 cctagagaag aaaccacacc accagtaata aaaatatatt ttgttgacac agaaaaagta
   646261 acaaagttga aagggctatg atacccaaaa ctgggtagaa tatggggtta ctaagattag
   646321 ttatttataa atgcaataca aacaatttat ttctcatcta tttattcatt taaagcccca
   646381 cattggaaaa tttattttta tttcaaccat gatgataata gcaacagtac ttgaaagttc
   646441 tgtaccagaa attacaggta gaattgttga tgaattattt gcaactgagc gtaaatcaga
   646501 aactgcattt atttatgccc ttactttatt aggtgctatt gttcttagtt cattgtttgc
   646561 acttacttct actgcagtta gttcttgggt atccaataaa gttattatgg atttgcgtgt
   646621 tattatgttt actaaattgc taaaattacc taaatcgtat cttgatcaac accctacagg
   646681 aaaaacacta tctatactaa cctttgatgt tgaacaaatt gcagctagtg cttcaactat
   646741 ttggttggat tttattaagt cgtcaatgac tgttgttatt ctaattggat atttatttta
   646801 taaaaactgg cagttgagtt taacactttt aatactttta ccgctagtat atctagcggt
   646861 aaaattttcc tctaatcgta tgcgtcattc gaatgttaat gtacagaaat caatgggtga
   646921 tatgacacat ttacttaatg aaaatatctc tggtaacaca ttagttaaaa tttatcatgc
   646981 ccaatctcaa ataaatgaca aatttaacag tttgattaaa aatatccgtc aacaacgttt
   647041 taaagttgat atgaccagta gttttaatac cgcttttgtt aatattttaa ttggtttgtc
   647101 tttaagtagt gtagtgtatt tttcctctac tttactacaa atgagtgcag gtgaattttt
   647161 gtcctttttt actgcaatgg gtatgttgct taaacctgct aaaagtttgg ttaatattaa
   647221 caagccttta caaaatgcaa tggcagcagg tgaaagtgta ttcggactta ttaacgaaaa
   647281 agaagaatcc aatattggaa ctaaggagct aataaatccc aaaggtttta ttcaatttaa
   647341 taatgtgtca tttagttata ataacaatac aaccatactt aaacatatta atctagatat
   647401 taaagcaggt gaaactattg catttgttgg tgcaacaggt agtggcaaaa ctactattat
   647461 ccaattattg atgcgttttt attctcctaa acaaggagtt attactatcg atggggtgga
   647521 tattaaccag tttgaaattg attcattacg ctcaaatatt tcctttgttg atcaaaatat
   647581 acaactattt aacgactcta ttaaaggtaa tattgcctta ggtcaactag aaactatatc
   647641 agataaacaa atcaaacaat cagcaattat tgctaatgcg gatgaattta ttcaacaact
   647701 agagcatgaa tttgatacac aaattggtga aaatggcata tcactatcag gcggacaacg
   647761 ccaacgactt gctattgcaa gagcaattgc caaagacagt cctattttaa ttttagatga
   647821 agccacttca gcactagata atgcgaccga aaaaaaagtg caaaacgcca ttcataaaat
   647881 gcaaaaaaac agaacaacta ttattattgc ccatcgacta agtactattc aaaaagctaa
   647941 ccgaattatt gtactacgcc atggctatat tattgaacaa ggaacacatc aagaattact
   648001 agattatcaa ggtgaatatg ctcaactgta taagcaccaa tttaagtatt aatactaaaa
   648061 gaataaggcc tgtatggcgt taggttaata ttactaatac taataatctt gaattaatat
   648121 gaatgaatag atttcaaata agtatttata tcagtacaac aattatttac acctacggta
   648181 gtgtctatag ttttgataat aattagtaaa aaatagattg aactctttta tttaaaaaaa
   648241 ctcgaaaaat aataacttga gttaaaaata cctgtgataa ttgaaatata gataattgaa
   648301 gtgatagagg ttccagcaat gacacctata agaatatttt tgagtttaat atcaataact
   648361 gataaaaaat aaattaatac attaattgaa ataccaggaa taaaacataa tacaaaaata
   648421 atggaaattt ctttgctttt aattttctgt tcaaactgaa gtattttttc tggcactttg
   648481 aaattaagtt tatgagaaaa attataaata attaaacaat aacttacaat cgctatttga
   648541 atagcaaaaa acacctgtat aaaagaaaaa agataaatac ctgctagtaa gaatatagct
   648601 ccaggcagaa atgtcaaccc cctaataatc agtattataa tatacactaa ataagaagtt
   648661 aaaaaatttt ttccacttag aaattcttta agcataacta gatcaatctt atatccattt
   648721 aagtaaaagt aaactaccaa agaaacatta agtaaaataa aactgtaaaa aagatgtttt
   648781 gtgttaatac tctccatgat caaaaatttg tattttatct aattgatgat agaaaattga
   648841 taaatcttca ctttttccat atctgggctt gttatgcatt gctaaaaatg gacgtgaatt
   648901 aagttctaaa aaaatacaca cttgtgcatt aaagtcaatc tcaatacctt ccttacaaat
   648961 cacatcaata cctaaaatat tagcatcaaa aaaattgagt atctttttca agtcttgtct
   649021 attttgtttg gttaatattt ttttatcaat aatttcaaca ctagaaccta attttaatga
   649081 tattttatga tgtaaataca ccttttgtcc aacgttagga atactagata aattcatttg
   649141 ttgtttcttt aaatattgtt taatggctaa atttttaggg ataggcttaa taattggcaa
   649201 taaattcatc ttttttctaa ccagattctc gttatcaatc aacttagcta tatcactcac
   649261 attatcaccg atcacaaaag gagggtaacg tctaagtacc gacattaccc caaacttagt
   649321 cataactata cgataatttt tacccaataa atatttctca acaatactta ctaaccacca
   649381 ttttttaacg ctcaaactag ctttagccaa ttgcatataa gtgttaatag gaaaatatgc
   649441 tcctctagaa aacccaccaa cattaggttt aacaactaaa ggaaaaccat tttttttagc
   649501 aaatttaaat gcactaatag gattaataaa tattttacct tgggcataag gaaaattatt
   649561 ttccttaaaa gccattctag cttgtgcctt agaacgacaa gcacggcgta ttttaagtgg
   649621 attataatca ctacatcctg ataaaaaaaa tcgtgacaaa aatcgatgta gccaatactt
   649681 cataattcaa cttttgattg ataatgttta atgacttttt taaaaaatac gaaacgatta
   649741 aaatgttcct taggtgttgt gttactaatt ctaacaaggt gatacatatt gtctttaata
   649801 aactgatgtt tatttttttt tgaaatacta ctatcaagta gattaatcgg aaatggtgca
   649861 aataaattaa cctcaataat atgaaacata cctttcaata aatcttgttt agaattggat
   649921 ctaagtccca ctctagcgat tcgaaaatat ggtaattctt gcaaatgatt gtgcaatttt
   649981 ttaagttcac ggagtgagaa atctaatgta cagtcttgat aaattacctg tttgttatta
   650041 atactattca caggataaga ctcgcctgaa tggttgatta cttgagtaat tgttagtgtg
   650101 atacaatgtg tttcattatc agaatttcga atatagaaaa tctcatattc ttgcatttct
   650161 attgctactt cttgaacaat gtaaggaatt ttactttttt tatgattaaa agctaaaaat
   650221 tcatctcttg aatcaattct tttgatacca ttagaattct gtccccactc tggctttaaa
   650281 aacacaggaa atttacaagg tggattgttt ttatcaagat aagcttgttt taatctccat
   650341 tttaaaggga tgcgtttatc catatcaatt ttagaataaa accctttttt tttattatac
   650401 cattcagcgt taatttgaaa ataataccaa ggtggaatac caagtcttaa tgaccaataa
   650461 atatagtaaa aaattaacct aaaagtcaaa aatttctcct ttgatagggt tatctgaata
   650521 aaaatgtaaa cttaagctta actcggtagc actaatttga tgaatatcat tatccatttt
   650581 tcctttcaca ctattactat atttacacgt tccatcaaca agcgtactac tactaatctt
   650641 agtcaatgga ttcttatcaa aatctttgca tattaactga cccttaatta cataaataaa
   650701 agcacggtct ggatgtccat gaatacgtgt tattgctcct ttatcccaat ttaatagacc
   650761 taaccaataa cttttattgt taataataat atttcttgtg taattatact gatcaaataa
   650821 taaagtctct aaatctattt ctaaaattag tgtttttatt ttctcaatag ctaaagtata
   650881 tttttcctca tgaagtaata cacacaacat cttaaaatca aaattagttg aatgcgtata
   650941 atacgtattt tgaatttctt taaacattat ttaatgttct tcctctctta accaaacgat
   651001 taagtaaact aactaatttc actttattca tattaatatt actaattaat aatctaaata
   651061 ctaatttctt ttccacgtat gctaaagcca gtagggcttg ttgtccctga tataaactat
   651121 cacgcaaaca ttgattaaaa ttatttttat tagaatgact acttttaaag cgaaaacata
   651181 cattaaaaga agtacgttta agtaccattt ctaaatcaac actagcgtta ataaaatctt
   651241 cagcaaattt tgccagttga tagtaattct caactctatc agaaaaccct ttcctagtat
   651301 agaatttcca atctaaaaac cattttaaac tatcaacacg acgaccacat tgcaatgaag
   651361 caatacccaa atcagcctca ttatctctaa aaatatagct accatctcca tctgcacaag
   651421 tacatgataa tagatgttta tgatttaaca ataaaaaatt acacattaaa ttactaccca
   651481 acattttgtg aaagtccata gtaaaagaat ctagagactc aatacttgtt aaaaatttct
   651541 tttttaattt caaactcata attgccacac cgccccatgc accatcacca tgtaaccaaa
   651601 aattgtgttg ctttttcagc atagttaacg cttcaatatt gtcataagca cctcgtactg
   651661 ttgtacctaa tgttgcacaa acaaaaaata ctaagccacc ttgttgtttt atttgcttga
   651721 ttttctcatt aagcaatatt gtatttattg agccatcttc aagggtagat accttaatta
   651781 aatgattggt accaatacct aatatattgc ttgctttgtc taatgaataa tgtgcatcct
   651841 cattaacaaa agcaaacaaa tatttctggt taaataatcc ttgttttttt acctttctca
   651901 atgcttgatt acgtgcaacc atcatagcaa tcatattggc attactagat cctgtggtca
   651961 tctgtccttc accattttta aagcctacta tatcaagcat ttgtttaatc atgtatcttt
   652021 ccattaacgt cgcaacaggt gcagactcaa aagtgcaatt tgaagtattg cttagcgcag
   652081 ttacaatttc acctacaata gaaggttgat tagcacccga ccacatacga ttagcaaaat
   652141 taggatgact agtattagga gaatattcta aatattgttc tacccatgta aatatctcat
   652201 cccaacactg tggattttgt ttgtttaaat ttaaggtttt ttccaactta ttaatagttt
   652261 gataattaat gagttggtta gattttttaa aatttgaagt agctaagact tgggttattt
   652321 tttgtaaaac atcctgattt tgcatcaaat taagctcgtt tattgagaag aaacattaca
   652381 acgcctaaaa ctaaaataga aaaaactaca ttcaccaagc ctgaatcagt ttgtatttgt
   652441 ccattctgat tccacttaac tatccagttc aataggataa ataaataaaa caaaactgaa
   652501 tacatcatca ctaataccat taaaccacta atgaaatgta aatcttttct taaataccaa
   652561 aaaataatag gagatagcac aattaaaaaa gtaaataact tagaactatt aataacataa
   652621 gagctgtatt gaacaaataa ttcacttatc ataccgccta gaaaataact catccaagca
   652681 ccaaaagtaa aaaagatata taaggattct attgcataac tagtaaatgt ataaggtaat
   652741 gagcttaaaa aaacatacaa taccaataag agaaccaacc aaccagcaac aactttaatg
   652801 gtattattca tgtttttatt cccttttttt gttttgtgat aattttatta tttaattata
   652861 aacgactcaa tactttgcca gagtctaaga ccgctcttgt tatacaggca gcctcaatca
   652921 atgagctagc ctttctagta tgccaaagaa ttaaactagc agctaaaact aaaccatcat
   652981 aaaacagacc tttttcacct gataaagctg attttcctaa tttaactgta taatctgcta
   653041 gggctttgat atcactatat acatttagcc cactaggaaa tgaaatggca cgaatatctt
   653101 gatagatacc caacaactta gggtcaatat ccactttatc ttgctcaacc gaaccttggt
   653161 aagaaatcat taaccccttt tggcgaagtg aaggaataac gcctccttca acacctctaa
   653221 ctaacaacga tgtatccatg cctgaagcgg ttactaaatg cgcataaata ggaggataag
   653281 gcttatgtac atagcctaaa atagagtgtg ttttttttcc gcgcattgga ccaattaaag
   653341 tttctacagt attaatcaca ctacgcttaa taattttatt acgcaaaggc acaagattat
   653401 gcaaaccttg gcaatagttt tcttgatcaa tatacgacca accaatactg ctatcttcaa
   653461 gccggacctt agcttgctta gttgagttat tgatattcaa acccaaagcc tcattaatat
   653521 gtcgatgagt aagtccatac tttggagata cactatctaa accatgaata acggtaggca
   653581 aaccaagctc agccaacaat ggcggtaaaa atgatgatat tggaattgaa cgactatacc
   653641 cactataagg atcacctaaa tctaccaaat tatcaacaat aacttgttgc tgatcagact
   653701 cacaaagaat agcagcaaga ataccctcac tttcttcacg tgtttcacgt ttcatgcgta
   653761 gtgcaattaa aaaaatagct atttgcacct cattaatttc tccacgaaga atacttaaca
   653821 tacctgcctt tgcctcttca aaatcaatat tcttactcaa atcaggacct gttgctatgc
   653881 gttgaataat tgagtgtata agtttttgag atattttcat aattctaaat aaattttatt
   653941 attttcttgc ttgataggat aaatacgtaa attatctaca cttttctgtg tactatttcc
   654001 tgtaattaaa tcaaaactaa atccatgcaa tgaacatttg attcgatcac cttttaaaca
   654061 acctaacgtt aatttaatat cttcatgtgg acaacgatta tctgcacaat acaacttacc
   654121 ttggttaagt gtaacaaata aatccttacc ttctacaaca acttcaacca tttctccttc
   654181 ttttggttct ttatctagaa tttttaccca cataaaactt agaagaattt ccagatattg
   654241 ttgttatcca atcgcggagc gcattgttta agttgatgct tataacgttt tgcattatca
   654301 tcaacaccac ctgcgatttt catcaaccat ggcttaacaa gataagtttg tttattgaaa
   654361 ccgctatgtc catcatgata agcaagatat tgattgtatg tatctgattt atcaatacca
   654421 gaacgtttac tggactggtt agcataccaa ccaataaaat ttatagcatc atcaaaatta
   654481 ttacgattga tattttgttt acctgttttt aactgatacc actcccaagt tatgtcccta
   654541 atttgagcaa aaccataagc actactctgt ctaaaccatg gcacaacacc aaataattta
   654601 tctcttggtg gtcttgcatt tgatgcaaaa tgcgactctt ggtacataat agctaattgc
   654661 acatgcatag gtataccata ctttttctca ctagctctaa ctgcttgata ccaactcact
   654721 ttctcatcca ttaaatgaca aatattattc acttgtattg caggtgttga aaaacacccg
   654781 ctaagtgcta atgagattaa tacaataagt aaaagtttac tcaccaccca aatattttat
   654841 aaacaataat agcttgaata ataaacaaaa taacaaacat acttttaata gtgttatatg
   654901 ataacgtctt agatttaaga ttaggcgttt taatgctttt ttccaaatta acatccattg
   654961 ctacccaacc tttttcagaa ttctgcgtat taaaaacaac acgtgtatta actttcaagc
   655021 gagatttatt aaaaatattt ttttgatgaa caaaatattt ttcaccatca tcacccataa
   655081 taaaaccata ccccttagtg ccaaattggg caactgttcc ctgtactttc tttaccattc
   655141 cttcctctta ttttttttac acaaacaata cgttttttct taataaaatc aacattttta
   655201 cgttaaaatt tgaactcatt tttaatatca tcgaaacatt gtaaccgctg acactcaaac
   655261 cctttaaagg ttacctctgc ctatcattaa ttacataaga gggccactta ttcgtaagta
   655321 aggataaagg ttaaccacag tattctacaa tcagtagata ttatatcgta taaataggat
   655381 gtatattttg ctcttaaaac taaagacagt tcaattcaaa ctctttatca tatatagtac
   655441 taacatgatt taaaatgtta gaattaagat taagataatt accatatata gatatcaata
   655501 tcttttaaaa gattacacaa caaatttatc acttttatta gtagaaaaca caacttaatt
   655561 ctctacaaag agctgttgat tacaagttaa cttaacaccc aatatcttaa aatcttttct
   655621 taagaaatac aacataatca atactttaac cacataatga tataaataca caattactaa
   655681 aatttaattc cagataatta actaattttg ttttgagcta atttgtataa tagtctatat
   655741 ttaccttatt accaacgtat tatctaatca ctcatatata atgataaacc ataaaaaaag
   655801 aaaaatattc ttacaatggc tactagtcat tattgctatt tttagttttc gtgtttatca
   655861 acaacatgac ttaagtagtg gtgtcatacc cagttttaat agcaaaactc taagcaatgt
   655921 ggttgtctca tcacactcaa ataagccaac tttgatacat ttttgggcaa cttggtgtag
   655981 gatctgtcaa cttgaaaatg ataacataca aaccataagc agtaattata gagtgcttaa
   656041 tattgccata caatctggtt ctgacactga tttaaaagca tatgcaaaag agcatgatat
   656101 gaaaatagac aatattatta atgataaatc tagctcttta gcaaaactac ttggtgttaa
   656161 agccacacca actagttttt tcatctcaaa ggataatcaa attaaattta gcgaagttgg
   656221 ttatgtgagt atgctaggtt atcgcttaag attatggtgg acaagtttat gaacatacaa
   656281 aattggcacc caagtatcaa aacattactg aaaacacagt caataatcaa tttaaaactt
   656341 ttcttgatac gacaaagaaa agctaaaaaa gttatcctac ctaattctaa caactggttt
   656401 aaagcatttg aactaactgc gtttgataaa gttaaagttg tcattcttgg acaagatcct
   656461 tatcacggac taggacaggc gcatggtttg agtttttcag tagttcatgg cgtaaaaaag
   656521 ccaccatcac ttaataatat ctttaaagaa ttacataatg atttaaatat tgaacctaaa
   656581 caaaatagca atctaactcg ttgggcaata caaggtgttt tactacttaa tagcgtttta
   656641 actgttgaag tcaataaagc ggcttctcat tctaatcaag gttgggaagt atttactgat
   656701 agcgttatta gaaccctaag taaagaacaa caacatttag tgtttatgct ttggggcgct
   656761 catgcaaaaa gaaaatctat attgattgat agaaataagc atttgattct cactagcaca
   656821 cacccttctc ccttgtcagc acatcgtggt tttttaggtt gtcggcattt ctcaaaggcc
   656881 aataattatc ttaaaataca caaccaacaa gtgatcaact ggcaataatg aaattagtca
   656941 ttgacgatgc ttgctatgct cataaagaaa tatttagcca ctttggtaat atctctacca
   657001 tcgctggtag agatattaac tccacctcag ttaagaatgc agatatatta attgtacgtt
   657061 cacgtactaa agttaatcat gtattattag atggtagcca agttaaattt gttggctcaa
   657121 cagttactgg gctagaccat attgatcaag attatttaaa atctaaaggt attaaatttt
   657181 tttcagccca aggttgtaat tcaatggcag tagcagaatt tgtaataagt gctattgtta
   657241 atttagcaga tgaattggat tttgattatc aaaagaaaac cttaggtatt attggcatag
   657301 ggaatgtagg tgcaagacta gcaaaaaaag ctaaattaat gggtattaaa accttgctta
   657361 atgatccacc acgacaaatg tatgagaact tgccaaactt tgtggattta aaaacaacat
   657421 taagcgctga tattgtcact tttcatacac cgctaactgt taatggtaaa tacccatcct
   657481 atcaactact caatgaaaat aattttcatt atattttaga taaaactatt ctttttaacg
   657541 tagcacgtgg cggtataata aaggagacaa tatggcaaga atataaaaca cttgctaata
   657601 ttattgattg ctgggaagat gaaccaaaca tcaacctaaa attacaaaat actgcttatc
   657661 tagccacgcc acacatagct ggacactcaa ttgatgcaaa atttatagga agttttatgg
   657721 tatatgaagc gctgtgtgat tttttaggta aaaaacaaga tagtaacatc aaaaatttaa
   657781 ttaaccttga taagttatcc ataaataagg ataccttaaa aaatacatta aataaaattt
   657841 acgattttcg acaagatgca aaagctattc aagatattaa taattttgaa gactatcgca
   657901 gaaattaccc tgttcgttat gagtggcatc attttaaaag taaaactacc ttgccaattg
   657961 cttaaccttt aaagcatggt tgtttaaaat atttgtctaa ttcaactttc tttatcttta
   658021 aatcacagta taatagaatt tgtaaataat attcatcttg aaatagataa attaaatttt
   658081 tttatagttc ttttatataa catcaacaca aatcacaaaa gctttaaata ttttgatatg
   658141 gcatatatac aatattacta tcaataataa aaatagtttg tgtttgataa atatcatcaa
   658201 acgatacaga cataatatca acttcacaaa aatcttctgt taatatttac ccaaacaaat
   658261 acaatactat ttagtgtttt gatattaact caaacacttt aatcactgct ttaatggttt
   658321 ttacaattta ctcaatgaaa aactaatcaa tctatcatta tctatatacc tactatgtct
   658381 aatagagttt aacctctaat gcaatgtatt actttattgg caggaaaatt tttctctctt
   658441 accaaattta agatagatcc taatcaaata aactcaatac taaaccctat tccacaataa
   658501 ggacaggttg ttttaaaact tatcattctt tcattttact taatgaataa aattaacaat
   658561 agaataaaat ttaatacaag caacaataca cttaacagtc gatattttat tggttttaac
   658621 tttgactgct tgttcttttt aggtaataaa aatattgaat ttggatgttc taagtcatat
   658681 aaaaaatctg acaaagcctc atacctattc atataatcca gataacacgc cttatgtata
   658741 gcaccatcaa tccatacagg taaattcgaa ttgtatatta acactgactc ataagttaat
   658801 ttagataatg ttttaacact caaattctta tctaatttat tctgataagg tatatgagat
   658861 gaaaatatct catatacaat cacacctaaa ctaaattgat cagaggcttg tgaaacaatt
   658921 tcatttaaaa ttacttctgg tgcagtataa ccctgtgtac cttgattacc tataaaatta
   658981 atagggttga ctaattctga tacaccagca attctgactg aaccaaaatc aatgattttg
   659041 atttgaccaa tttcgttaat catgatattt tctggtttta gatcacagtg taacatttct
   659101 tgacgatgaa acgctctaag accttgaata atttgtttta caaaactaac aaccacttcg
   659161 atattaggct gtttatttcc attcatccac gatcgtaaag tttgcccctt aacatatacc
   659221 atggcataag ctaaaaagtt cgctttttta taactattgt aaattttaac gacattggga
   659281 cttttaacgc gctgccctac ccacttttca tacataaaat gttgcaaata ttctggatca
   659341 tcttcaaaat tcacagaagg ggttttaaga gcaactaact gtttagtcat aatatctttg
   659401 gccagataca gttgcatttt tgcacttgaa ataattaaag attctatctc aaaaccatta
   659461 attttcattc ctttagttaa atcaggtggt acaggttttt gagttaattc atcaaatact
   659521 tcacctagat ttttatctgg taattgctca atcattatta tcatagctga aatattatcc
   659581 tgggagtttt tcttaatcgc ttgttcaaca attttatgag cagacgagtc tttatccatt
   659641 aaagatgcca atgatgcatg ttgcaaataa tcatgaacac catcagttgt cattaaaaac
   659701 tgatctccca gttcaagatc aaaaatttga tagtcaacat taatacttaa atcaaagccc
   659761 attgcccttg atagataagt tttttcctta ttaaggctta aaatatgatc tttagtcagt
   659821 tgtcttaata ctttgtttct ataacgataa actcgtgaat ctcccacatg aaaaacatgt
   659881 atagcatttg atttaataat cactacacta agtgtgcata gcatagatga aacttcacca
   659941 aaacgcattg attgagaata cagccaatta ttaagtgctg agataactgt actagctgaa
   660001 tgctcaatac tccaagattc aggagttgaa taataatcac ttaaaaaccc tttaacacaa
   660061 cagccacttg cttcttttgc tcgttcacaa gcactaacac catcagcaat aacacctaca
   660121 attcctttga attgcaaggt ttgaggatta ggtacataat aggcgcaagc atcttgattt
   660181 tccctcttta cacctgcaat agaatgtgag ttaacaataa cctttaattg tttcatgctt
   660241 aatttagttt gattatctca accgtaccat catctaaaat ttcagtcatg tgttcttttg
   660301 gttcttctaa aaaaataaca atcaatacta atactacagc actagtcata ctaatcaata
   660361 taaaaaattc atcataatct accaaagaat ttgcagttaa aaataagact gcacccacat
   660421 ttccaaatgc acctaccata cctgcaattt gacctgttag tcttctctga attagtggca
   660481 ccatagaaaa tactgctcct gatcctgctt tagaaaaaat accaccaaca attgtcaatg
   660541 ccactactaa atacatagac cagcttttat ccacattacc taatactaaa aaacttaaag
   660601 taataccaga gaaaagtaca actaacgtta gctttcgacc atatttatcg ctcaaataac
   660661 caccacctgg cctggcaaat aaattaataa atggatatac gcctgccaat aaagctgctg
   660721 taattttagg caactcaaac caatcaacat aaaacatagc tagaattgaa actacagaca
   660781 actcagcgcc aaaagtaacc aaataagccc aatctaaaat cgctacctgt ttaaatttat
   660841 attgatgttg cttaagcgta aaatgcttta aatattgcgc attaacagtc caggttttaa
   660901 atatttgtaa aacaaatact aatactaata ctatatatat gctaaattcc acgcctaatg
   660961 aaatcatatt cattctttca ggcgataact tccaagtaag tagtgacaaa gcaagataca
   661021 aaggtatgtt cattagaaca tacaacccca aatctgaata actactcact tccattgctc
   661081 ctattttttt aggcttaaaa taagttgaac ccttgggggt attggttaca ttaaaataat
   661141 aaaaaatacc ataacttatt gccaacatac tagcgatagt aatagcatag cgccagccat
   661201 taacctcacc aaaactgctt gcgataaaag gtaatgatat agctgcacct gctgaaccaa
   661261 aattacccca accaccataa ataccttgtg cagtacctgt ttgtttagcc ggaaaccact
   661321 cagaaatcat acgaatacca actacaaatc cagctccaat aaagcctgat aaaaatctaa
   661381 caagcgcaag ttgctcataa gactgcatcc aactaaatac aattgaaaca aacccaccta
   661441 aaactaaaat agaggagaac ataattttag gaccaagttt atcaactagc ataccaacta
   661501 caattcttgc tggaatcgtc atagccacat taagaattag taatactttt gcttgctgtt
   661561 cgctcaataa taatgcttgt tgaataaatg gcatcattgg tcccaagcta agccatacaa
   661621 caaatgtcat aaaaaaagca aaccaagtta agtgtaaaat atagtatttg cctttaaatg
   661681 aaaataagtt taatttatct tccataatta taccgaactt ttatgagttg ttattcccca
   661741 tggattttta acagttttag gtagtaaatt tgcatagtat ttaatcattg aagatgtatc
   661801 tagtttagat tggatataat ctaaacctac acgctcttca aaatgcatta ctcgttcaag
   661861 atagttagcc tcaatacggt ataattgcac aaaagctttg agatactcaa ccacttcttc
   661921 ttcagtttca aaaaatctgt cttttaaaca ggttttagta cgaataccac aagcacctgc
   661981 tacgtggatt tcataacctt tttcagtaca aataactcca aaatctttaa tcgtaacttc
   662041 tgcacaatta cgtggacaac cactcacacc cattttaaat ttatgtggca taaagtgtga
   662101 ccaaactgca tcttccattt taattgcaag ccccatagaa tcttgcgtac ccatcataca
   662161 atggtcttta ccaacacagg atttacatgt tctagtggct ttagcataag cgtaaccagc
   662221 ctccatacct gccccagtaa cttcatccca aatatcgttt aaattttcct tagaaacacc
   662281 taataaatca atacgttgtc ctccagttac tttaaccgtt ggaacctcat atttaatagc
   662341 aatatcagct aatgctttaa gttctttagg tgttgtcagt ccaccttgca tttgtggtac
   662401 aacagagtag gtaccgtctc tttgtttatt agcatgcatt ttctcattgt gcggtcgttc
   662461 atcatcatta tgaagatatg tttcattaaa ttgtgaagat aaataatagt taatagcagc
   662521 accacaaatc tcacaagtgt tatcaaaatc aagcgcgtct ctaacattat caacactaac
   662581 aacttggact aatactctaa tatattgacg cacctcttct gttgagtatt ttgtacaatt
   662641 acacaaggtg tttttactta atattttagt gccagaaaca aaactaaata cttgtttagc
   662701 aactgaagta caacccccac aacctgttga acagccagtt tcctcctgta atgcctcaaa
   662761 agtattacaa ccacctgcta ctgcacttac aatatcacct ttatcaacac ccatacaacc
   662821 acatacttgc tcatcattag ccatcttttc aacaccttta tcgcctacgc ctaagtcatt
   662881 aatattacca aataataaag ttttacggat actgctaata tctgtttctt ttttaattaa
   662941 gttaaaataa aataatccat ctgttgagtc accaaataaa actgcaccaa ctaatttatt
   663001 atctctaata gataatcttt tacgagtgtt aaatgcattg tctttagaac acataatctc
   663061 atctttagga ttgttaaact cccctgctga aaagacatca acacctgaaa tttttagctt
   663121 agtagaaata tttgaacctg tgtatatatg atgagatacc tcacatatct gttcagcaca
   663181 tacgcgtgct tgttcaaata atggcgctac taaaccatac gatatacctc ggtgtttaat
   663241 acattcacct actgagtaaa tagcaggatc tgaggtcatc attgtatcgc ctacaataat
   663301 tcctcgatct gtatgtaacc ctgcagcttt agctaaagaa tcctcaggaa taatacctac
   663361 tgacataata accatatcag catccattat tattccaccc ttaaattcca aagcttttac
   663421 tttattgaat ccaataattt tattgataat catacctagc ttgaatttaa tattcttctg
   663481 ttctaatact ttttgcaata agtcaccaga taaagcgtct agttgcatat tcataataga
   663541 atccatatta ccaataacag ttacatcaaa ccctaactca ttaagtccat tagcggcctc
   663601 aagtcctaat aatcctgttc caattactac tactttttta gcttggttaa cttttgattg
   663661 catatattca acatcataaa tatctctaaa cgatactacg ccctctaacg ttttacctgg
   663721 caatggtaaa ataacaggcc ttgaaccagt acaaataacc aatctatcat attttattga
   663781 atacgactct tttttattgg ttaataaaat atttttatta aatctatcaa tagatgacac
   663841 caaacaaccc ggcttaaaaa taatattatt ttgagaaaaa taagactcgt tatgcgtttt
   663901 tatatcttca aactcttttt ctcctgccaa aacaagtgag agcataattc tattatatgg
   663961 caataccttt tcctctccaa taatgataat ttgatacatc attggatcaa tatttaacac
   664021 ctcatcaacc accttcatgg cgctcatccc cgatccaact atgactaaat ttttcattat
   664081 attttcctat cttgttttaa tattttatgc tttttatgaa gcaaaaaagc cagttactac
   664141 atttatgtgc atagacataa aatacaataa ctggcttcaa taccaaatta tcagccctat
   664201 cttagaactg acgaaaaaaa acgcttactt aataatttaa tcaaaaaact aagtaaacgt
   664261 ctatgttcat tgtttccctt cattaggaaa ctgaataata attatatcaa taaactaagt
   664321 tataataact tgatttatca tatatatttt tgtttattaa aaaacacttt ttaaatatgg
   664381 ataaaataat tatacaacaa caagattttg acttatcaac agaggtagca ttaataaaaa
   664441 atacacgctc tgatattggc gcaatagtta gttttgttgg ttttgtacgt gagttaaaag
   664501 acaatcaaat tcaaaaaatg acgttagaat actatcctgg gatgactgaa aaaactctaa
   664561 aatatattgt taataaagcc aataaacttt ggcatataag caatacaacc attattcatc
   664621 gtgtgggtga tttaaatatt aaagatcaaa ttgtattggt tattacaagt agcaaacacc
   664681 gtcaaactgc ctttgaatct tgtgaattta ttatggactt tctaaaaacc caagcacctt
   664741 tttggaaaaa agaacatact caaaataaaa gtacatgggt tgaagctaaa agtagtgata
   664801 aaaatcaaaa aaaacgttgg gaataatttt actgcttaat tttcaaatct ttaggtgaat
   664861 ttaagttcgt aaacatattt acttgatctg aaaaatcaac tttttgtgca tgattacttt
   664921 caaaccacac actcatctta cggttgcctt gttctagaaa ttcgcttaaa ttatctttta
   664981 aattgacact aactaatgaa aaagtaggat gcattttttg cccttgcatt gctacacaaa
   665041 tattcacact aggttgctgc atatttttta ataatctagt tataagactt tgattaataa
   665101 acggtccatc acatggcaca attaataaat attttgtctt aaccttgttc aaagcagata
   665161 aaataccagc aagcggcccc tgaaacccag gtaaactatc agtgataacc tcgccaaatc
   665221 tttgatactc actaatattt ctattggcac ttattaatat actacacaca tcttgatgaa
   665281 caatatcaac cacataacta atcaaaggtt tgccattaaa taaaattaaa cccttatcct
   665341 tatgattcat acgtatggac tgacctcctg caagtataac aacagtgata tcacttttac
   665401 caatgttttt catatgggtg tattagtgtc aaatctataa gctatatgat acaatcaaac
   665461 aattaacttt aattataaac tataaaaatt tatgatagac aaccaacatc aagttgatta
   665521 tgaaagtgat caaacgccag aatttttaca ttctattaat aaggctttag aaaaattaat
   665581 aagccttgcc aaagttattg atagtactca attaatagaa ctcgatgacg cattaaatag
   665641 aattctagct gttgatatac atgccaatat ttctgtccct agttttaata attctgctat
   665701 ggacggttac gctattaatc ttaaagaaaa tcaaataaat acacctggta aatttgtatt
   665761 tgaaattacc gatcgtattt ctgcaggtaa tacagtaagt atactagaac caggctgtgc
   665821 agcacgtata tttacaggtg cacctatacc aaatggtgcc aatacagtac tcgtacaaga
   665881 ggagtgcaag gtaattaaaa acaaattcaa aattaaagtt gatcgaccta tcctacttaa
   665941 tgaaaatatc agacctatag gtaatgacat tcagtcaggt gatgttattc tatccaaagg
   666001 aaaacaactg caaccacaag atattgcact agcttcctcc ataggaatag gaaaatttga
   666061 agtatttaat aaaattaagg tcggtgtttt ttttacaggt gatgagttag tcaagcctgg
   666121 aaatacatta caacaaggac aaatttttaa ttctaatcgt tatttattag tggcactatt
   666181 aaacaagctt agttgtaaca ttatcaactt aggcaatatt aaagataccc ttaatgccac
   666241 ttgtgatgca ttagaaacat taaaatctaa ttgtgattta attataacaa caggcggagt
   666301 gtctattggg gataaagatt atattaaacc tgctatagaa aaactaggcc aattaaacct
   666361 ttggcgtatt aagataaaac caggaaaacc aattgctttt ggcaatatag ggcattgcac
   666421 ttttattgga ctaccaggca atccagtttc tgccatggta acttttttac tctttgctcg
   666481 gccttttatt aaaaaaatac aaggcgcaaa tcactattta aacaacgctt taaaaactca
   666541 aacaaacttt gattggcata aacctaaacc aagatgtgaa tttgtacgtg tatgccttga
   666601 ccatacaaca ttccctgcaa aagcaaatat atatacaaaa caaggatcca acgtacttag
   666661 ttccatggta tgggcagatg gactaatgga aattccagaa aaaactactt ttaaaaaagg
   666721 tgaaatatta aatttttact cacttaatga gatgttgtca tgaataacaa gcaaaatata
   666781 gtaatccaga caaataaatt aacccatata aacaataaag gaaaaagtaa tatggtggat
   666841 atttccaaca aaaataccac cacacgtatt gctaaagcaa ctgcaaaagt agtaatgaaa
   666901 ttagaaacct tgcaaaaaat taaaaacaat gattttaaaa aaggtgatgt attatcagtg
   666961 gcaagaattg ctggtatcat ggcagcaaaa caaacccata atctgattcc aatgtgtcac
   667021 agtcttaatc tttcaaaaat taatattgat tttaagtttg ttaaaaatgg tatacaaatt
   667081 accacattag ctaaactaaa cgcgaaaact ggcgtagaaa tggaagcgct taccgcagca
   667141 agtatagcag cactaactat ttatgatatg tgtaaatcag ttgatcattt tatcaaaatt
   667201 aaagatattc aattattaga aaaacaaggt ggaaaatctg gttattggaa acttgaatat
   667261 gtttaaatta attgacaaat ttggtagaaa aattaactac ctaagactct cagtaactga
   667321 gcactgtaac taccgatgtt tttattgtcg tgataataaa tataccccac actgtaaacg
   667381 cgaagatatt ctaagttata aagatattga aagaatcgtt caactttttg cacaattggg
   667441 cattagtaaa gttagattaa caggtggaga acctctacta cgaaaagaca tatataaaat
   667501 agctagaatt atcagccatg ttgatggtat taatgatata cctttatcaa ctaatgcaca
   667561 tcttttagaa aagttcgcta aaaagcttta ccaaaatggt attaatagag tgaatatttc
   667621 tattgattca ctcattccta aaaagtttga agaaatcact cgtggtggga atttaacaaa
   667681 agttattaaa ggtattgatg cagcaataca agtaaacatg agaccaatca aaattaatat
   667741 ggtaaccatg cgtggcgtca atgataatga aatagaatca atgattgatt ttgccattaa
   667801 taagggcatc gatattcgct ttattgaaac catgccaatt ggatcatcag gtataaaaat
   667861 actcactcac tacattagtg aaaaaaacat tcttactaaa ataaataatc acctaaacaa
   667921 taaattagtt cccattgcat ctagtgatat cgatggtcct gcccataatt ttaaaattat
   667981 gggcacgaac tctacaatag ggacaattag cgccatgtca aaccattttt gccaaacttg
   668041 caatcgtgtt agacttactg ctaaggggga tttaatccta tgcttaggac aaaaaaattc
   668101 aatttcttta aaagatgcac tacactcaaa cttaacagat gatcaaatta aaaacataat
   668161 tataaatgca attaataaaa aacctgaaaa acacgagttc aactctgttg ttgacaatat
   668221 tagcaaccga caaatggtag aaattggcgg ataaaataat acttaaaaaa atatgaatat
   668281 tttatatttt gcctcactca aagaatcact taatctatca agtgagaaga ttattcttgc
   668341 tgataacact acaataacac aactaagaac acaacttatt aacaaatatg gaaaacataa
   668401 ttttccaaat aacactattt gtgcagttaa tcaagaaatt gctaatgatg cagttattat
   668461 taagaaaaca gatgaagtag ctttttatcc accagttact ggtggataaa ataatatctt
   668521 taatttctta caaattaacc ctgactaaaa ataatcttca aacagatttt tatctctaaa
   668581 accacctatt tcaatagcaa ataatatgaa agaattaaaa aatagacata acagcaaaga
   668641 cataatttaa ttgatgtatt acttcgttac taataatagc atcgattgcc gttatattgt
   668701 aacatacata gtaacgaata taagcgaaac agtataatat attagtaatc aattaaaaat
   668761 aagtagtgct tatctcaaca aaaataatta tatgcgctaa tgaagttaca cagataaaaa
   668821 gctacagcat gtaacaagct acagcatgta acaagctaaa caactaatat atataaaaca
   668881 ataattgtta gaaaaagata cagctatagc aattactata aattatctga taaccgatat
   668941 taataattct ttattgcttc acctttatta gtagttcaaa cagataatca taatataatt
   669001 aaattcaaca ttaaagcctt tattcagtac tttaaccacc tggaggtttc ataacatata
   669061 tttcacaagc ttgttttaca tatccataaa gaaacaagtt aaataattta gctttagtaa
   669121 agtttctatt tacaccaaaa ttaatcaata tttgtttagt tatatgaaga aacatcagaa
   669181 atagcgctat gtatattata atcactctta ataaaattaa atataaccca aataatcaca
   669241 cattagtgtt atattttcta acttaatcaa ttctaaatta tttctttatg attaatgtta
   669301 atttattata ttttgatatt agtaacacta ggatctttaa agtcaaatcc ttgtatattt
   669361 gcatctacag caagcatctt aatgtattca ttaataccag aaattgttga ttgattttgt
   669421 aaatattctt taatatacac ctttaccatt tcaaacggta gtgtttcgcc tctttcttta
   669481 tctaaaaatt taattttatt attattataa taacgtttac aaaattctac acttgctgta
   669541 ggaataacta tattatcact taacaattga ttaattttct cctcctcatt aggattattt
   669601 tttttaatac caactgcctg taataataat tgttgaacaa ctaaagcttg tgctgcttta
   669661 aaaataactt cttttacatt tatagcatct gtttgatatt gcatttcttg aaatacatca
   669721 tcatcactaa tttgtacgtg gttaacttta atagacatag ttacttatct tcttcttact
   669781 atttgataat ttgtacgagt taaatattgt acaggcacac tccaaatatg cactaatcga
   669841 gtaaatggaa aaatagcaaa aagcgtcata cctaggatta aatgcaactt aaacacccaa
   669901 gcctcagaaa caataaaatc agtagccccc attctaaaag aagtgatata ttgtgcccaa
   669961 ttagccaaag caatcattga actaccatct aagtgttgcg ttgaataagg aacagttaac
   670021 aaacctaata ataattgtac aaatagatag atcaaaataa aagtgtcact aaacttgctg
   670081 gtttttctaa tacgtttatc aaataagcgt ctatttaata gaattaacat accaactaaa
   670141 cacattgtac caaaaatgct accgacagtc attgctatta tctgcttagt accagcactc
   670201 ataaatggat gatacaccca ttctggggtt aataaaccaa caaaatgacc aaagaataat
   670261 aagattattc caatgtggaa taaattacta ccccataaca tgcctttttt tcgtaataat
   670321 tgtgatgaat ctgctttcca ggtatattgg tctctgtcat aacgtagtgc actgcctaca
   670381 ataaacatag tcatagcaac ataaggatag taaccaaaaa aaaactgatc taaaaaagta
   670441 ttcataatat acctccgtat ttaatttttt gttgcattaa tttcacaagc actacactct
   670501 gacgaatcgc cactaaacgc ttcttgttct tgccataact catctaattc atccaatgtt
   670561 tctggctctt ttaggctgtt ttctattgcc tctgctactt taaattgatt tgccttaatg
   670621 ttagataatt cttctaatgc aaaaaagata atttgataag gagatttatt ctttttaaga
   670681 tgaccaccga tcaaagcaat aatatcaacc gtatccccta atgatgttat cgcttcttga
   670741 acatcacata aagacaaata ctctaaaaat aagggcaaat aatcaggtaa ctctttcttg
   670801 tcaataaata aattcttctt tgcatacata tcaatcaagt caaccatagc ctgaccacga
   670861 tcacgtgatt caccatgaat atgctcgaat aaatttaaac aatgaatacg acttctatca
   670921 aaggttgcca caaaacgttc ctgcaattct aaaagatctt tatttttata atcctctata
   670981 aaagacaata attctttaat cttcttttta gataacaaag attcttgctt taagacttca
   671041 gtaagctcat caatattttt ataaacatta atattcggat aagacaataa aacagctaaa
   671101 actttaagta ttttcatgaa atgtttccat tcattgtatt agaatgtgtt ttaccaccaa
   671161 ataaagtcgc tgttgtagag ccttcagaac aaccattacc aaagctaaat ccacaagaag
   671221 atctagtatc aaaagcaatt tcattatcaa aaggcatctc tcctgcgtat tctttatggt
   671281 tagtaggaat cacaaatcta tcttcataag cagccagcgc catagttcta tacatatcat
   671341 caaccatatc ttctgtcaaa cctacctcat ccaatacctc agttaagata acgttatcaa
   671401 cacgctttgc acgcataaag ttacgcatag caatcattct ctttaaagca aatataatag
   671461 gcttgtcatc acctgctgta agcatatttg ccaaataacg aattgggata cgcaactctt
   671521 caacatttgg aataggacct cgattgttaa tcacaccctt ttcaattgcg ttctgaattg
   671581 gggataatgg tggtatatac caaaccatag gtaatgttct atattcagga tgtaacggaa
   671641 aagccacttt ccagtcaatt gccattttat aaacagggga attttgagca gcctctatcc
   671701 aactgtcagg tataccatct tttttagctt ctgcttgaat agatttatcg tttggatcta
   671761 agaatatttt taattgagcc tcatataaat ctttttcatc gctcatgtta gccatttctt
   671821 caattttatc cgcatcataa agaataaccc ctaatgaacg aattctacca acacaggttt
   671881 cagaacaaac tgttggctct ccagattcta ttcttgggta acaaaatgta catttttctg
   671941 atttaccaga ctgccaattg taataaatct ttttgtaagg acaagcgcta acacacattc
   672001 tccaaccacg acatttatct tggtcaatta gaacaatacc atcttcttca cgtttataaa
   672061 tagcgccaga tggacatgca gctacgcaag atgggttaag acaatgttca cacaagcgtg
   672121 gtaaatacat cataaatgta ttttcaaatt gaccataaat ctctttttct atagttttaa
   672181 aattataatc ttttgaacgt tttttaaact caccacctaa gatttcctcc caattaggac
   672241 cccattctgg tttttccata acttcaccag taatcataga gtgtggcctt gccacaggtg
   672301 gtgtaatcat ttcaggtgca ttttgcaaat gagcataatt aaacgtaaac ggctcgtagt
   672361 aatcatcaat ttcaggtaaa tcaggattag caaatatttt tgctaataat ctaaatttac
   672421 ccccaatttt aggctgtaat ttaccatttt tagaaaccca gccaccattc catttatctt
   672481 gattttccca atctactggg taaccaatac caggttttgt ttctacatta ttaaaccaag
   672541 catactcaac accttgacgt gaggtccata catttttaca agtaactgaa caggtatggc
   672601 aaccaataca cttgtccaaa tttaaaacca ttcctatttg tgctcttatt ctcattagtt
   672661 attttttttt gctggttcat ccttccaatc tactttattc attttacgta caattacaaa
   672721 ttcatcacga ttagaaccta ctgtaccata atagttaaat ccataagata attgtgcata
   672781 accaccaatc atatgagttg gtttagtaat cgttctagta acagaattat gaataccacc
   672841 cctaaatcct gatttttctg ctataggcgt agtggtaatt ttttcttgag catgatacat
   672901 aagtgacata ccttctggca ctctttgtga tacaaccgct ctagcagcaa tcgtaccatt
   672961 agaattgtac aactcaatcc aatcattgtc ttcaacatta attttttgag catcgacttc
   673021 acttatccac actactggac cgccacgatt aagtgttagc attaatagat tatcagaata
   673081 agtggaatga ataccccatt tctgatgtgg tgtaatccag tttaatacaa cttgagaacg
   673141 tccatcatta ttttcattga taataggttc gactgttcta gtattaatag gtggcttata
   673201 agtacataaa ttctcaccaa aatctatcat ccatttatga tcttggtaga actgctgtct
   673261 acccgttaat gttctccaag gaatatattc gtgcacatta atataacccg cattataact
   673321 aacatgttca tcttcaagac cagaccaaat gggtgatgaa ataatttttc taggttgtgc
   673381 ttgaatatct ctataacgaa tctgctcatc ttcttttgat ttcgctaggt gcgtatgatc
   673441 tttacctgtt attttcccta atgatttcca agctttaaca gcaactttac cattagtttc
   673501 aggtgctaaa gataaaatta cttcggttgc atcaatatca gtttctattt taggaagacc
   673561 tttagacacg ccttcttctt taacaatttt atttaaatca cctagagaag taacttcatc
   673621 tttagtatcc cattcaatac ctttaccacc attgcccatc ttagacatta gtggtcctaa
   673681 tgaggtaaac tttttataag tatctggata attcctttca acttcaataa aatttggcat
   673741 tgttttacca ggaatagctt cacactcacc atcaaaccaa gctttaacat cagttgcctg
   673801 agccatttct gccgacgtat catgcaaaat aggtaaagca acaatatcct tttcttttcc
   673861 taaatgtcca ggacaaagtt ctgagaattt tttagctaag cctttataaa tttcccaatc
   673921 acttcttgat tcccacgcag gatctactgc tttagacaac ggatgaataa atggatgcat
   673981 atctgaagta tttagatcgt tcttttcata ccatgttgct gatggtagaa caatatctga
   674041 atacaaacaa gtagttgaca tcctaaaatc taatgttaca aataaatcaa ccttaccttc
   674101 tacgccttca cgccacttaa cctcagatgg ttttttatct gtctcattgc ctaaaactgc
   674161 attttgtgca cctaataaat attttaataa atactcatgt cctttaccac tagagcctaa
   674221 tatattagaa cgccatataa acatattatg aggaaaattt tttggattat cagggtcttc
   674281 acaagaaaat tttaagtcct tagacttaag tttcttaaca atataatctt taacatttat
   674341 gcctgcttct tctgcttgct tagtaatttc taatggatta tcttcaaact gtggcgcaga
   674401 aggcaaccag cccatttttt cactacgaac attgcaatct attatagaat agtttttcca
   674461 ttttgtctta tcaatcagtg gagataaaat ctcatcaacc tctagttttt catatctcca
   674521 ttgactagaa tggttataaa aaaatgaagt gccgttcatt tgacgaggtg gacgatgcca
   674581 atctagaccg aatgctaatg gtaaccatcc tgtttgtgga cgcagttttt cttgacctac
   674641 ataatgagac caacccccac cagatttacc aatacaacca cacatcatta acatattaat
   674701 aataccgcga tagatcatat ccatatggta ccaatgatta atagcagcgc ctagaataac
   674761 catagactta ccttgtgttt tatctgcatt ttctgaaaat tctctagcaa tacgcacggt
   674821 ctgctctctt ggaactcctg ttactttttc attccaagct ggtgtataag gaacatcatc
   674881 attaaatgaa gcagcaacat tatcaccacc taatccttgg tcaacactat aatttgccat
   674941 cattaaatca aacactgttg aaactttaac ttccttacca ttaaccaatg ttaactgtct
   675001 aattggaaca tttctcatta aaatagaatc atgcgttgta tttgtaaata tttcttgatc
   675061 atgtactttg ttattaaaat atggaaaacc aacggatata atctcatcat tgttatcttt
   675121 taaagtaatt tttggatcaa tatccgcatc attcatagca ttcttatttt caatattcca
   675181 cttaccagaa ccatcccaac gaaatcctat tgttcctgtt ggaacaacaa tttcattagt
   675241 attttgatca atgagtagtg gtttccattc ggtattatct ttttcaccta aagtgtcatg
   675301 aatatctgaa gctcgaagag ttcttccagg cacaaatacc tcttttttct cttccaatat
   675361 taccaaaaat ggcatatctg tatattgctt gatataatta gtaaaatatt tacttttatt
   675421 ggttaaatga tactctttta ggatgacatg tcccattgtc atagcaagtg ctgcatctgt
   675481 accttgagtt ggactcatcc actcatcaga aagcttagca acttcactaa aatcaggtgt
   675541 tactgcaata gttttagtac cattataccg agattccgta aaaaaatgag catctggagt
   675601 acgagtttga ggaacattag aaccccatgc tataatatag gatgaattat accaatcagc
   675661 actttctggt acatcggttt gttcacccca agtttgaggt gaggatggtg gtaaatcaca
   675721 ataccagtca taaaaactta aagaagtacc gccaattaat gacaaataac gagaaccagc
   675781 tgcataagat accattgaca tagctggaat aggtgaaaaa ccaacaactc tatctggtcc
   675841 ataggtttta gttgtataaa tattagaagc tacaataatc tcattcactt catcccaatc
   675901 aacacgaacc atcccaccta aaccccgaac ttgtttatat tcttttgttt tagctttatc
   675961 attcatgatt gacttccatg catcaacagg atcaatattt tgctttttag cttcgcgcca
   676021 tatttttaac aacctagaac gaattagagg gtatttaaga cgagtggcgc tatacaaata
   676081 ccatgaatat gttgcacctc tttgacaacc tctaggttca tgatctggca agtctggacg
   676141 agttctagga taattagttt gttgagtttc ccaagttact aagccatttt ttacataaat
   676201 tttccaacta catgaacctg tacaattaac accatgagtc gaacgaacaa ccttatcatg
   676261 tccccaacga ttacgataag ctttttccca acttctattt tcatgtacta attttccatg
   676321 gccattagaa aaatattcag gctttgactg ggtaaaaaac gttattctat ctaataaata
   676381 actcattttt acctcctatt atcattacat tttttattcg atgattttaa taagaacttt
   676441 aatgtaaagc aatcaatcca attactaaac aagtatactt attatttatt taataaaaag
   676501 aaataattca aattacttta attaattttt aaaattaata cttgtgtatt ataattaaaa
   676561 acaaccaaaa gctcttttta cataatacct ctataaactt actttataaa taaactatac
   676621 ctaacattat aaaaatcatt tatgctacct tagagcctat aaacatatta tgctaataat
   676681 agatcaaata agtacatcaa aaagaatatt aatccatata taaattaatg ctaacgagtc
   676741 atgtaaattt ataatattac ttagtataac gccattatta acataatatg ttaaaaatta
   676801 aatatccata taattaataa atagcattaa taagaaatac tcacaaattg aaactatgca
   676861 ataccaacac aaataattag gaaatatcat ccatacagaa aacatgttat agataaaact
   676921 aaattagctt ataattttta actacgtaag cattaacaat tctatacttg atttaattta
   676981 aaaaaataat tagaataatt ttgcattcaa ttcagttggg cttagaaaga tataagtttt
   677041 tatatttata tcacaataat ctagaaaaat aattttaatt tagtaaaatt aactatttag
   677101 acttgttttt actattcaag agaatggtaa aattaaaact taaaaagtaa ctaactggcc
   677161 tttgaaatat atgagaaaaa taaacattaa aattggtttt attactatat ctgatcgtgc
   677221 tgctagaggt gaatatgagg atatcagcgg tcctgctatg caaaattgga ttaaaaatgc
   677281 tgtactatct ccctacacag tagaagatat aactattgaa gataatcaac ttctaattga
   677341 aaaaaccatg attgattttg ctgataataa gcattgtaac ttaattctaa ctaccggggg
   677401 tactggagtt acaacgcgtg atgtaacgcc agaagcaaca catatcgtat gtgaacgtat
   677461 ctttgatgga tttgctcaac aaatgcgtaa tatatcatta cgcacggttc ccacggcgat
   677521 tttatcccgc caaacagcag gtacacgtgg tagtagctta attatcaatc taccaggaaa
   677581 acccgctgca attgcaatat gtttaggtgc agtattttta gcggtgccta aatgtttaga
   677641 attacttgac caatctaata ttcaaattga tttagatttt atcgaacaaa atttagagta
   677701 aaaatttaac tagatttctt acctaatagg taagagtcta ctagtgcgat agtgatgttg
   677761 tcgtggattt taaattgctc agcaatgact ttaatcttag ataaatattc tgtttgttga
   677821 tgcttttttc ttaacaatgt taaatctagc ttaccattat ttacacaatc ttctacacaa
   677881 ccttttgcat tagcaaatat aatagtttga tccaaaataa catctagttg ataagaatac
   677941 aagtcaatat tatttgctcg agcaattgat aaatatacag cattaaaaaa atcatcatga
   678001 taaataatat gctcaatatc aatcacatta cttaactcat aatgttggcc ctgataatca
   678061 aatccaacat ttgctgtaac tgtattagca gacattattt agtcagtgat aaaaataatt
   678121 ttggtaactc ttgaggtaaa gattcaatac gatcaattac cgagtaatgg gagccgaaaa
   678181 tatcaacaat gtattcatct gcttttttat ctaaactaat acaataagga tatatgcctt
   678241 tttgttgaac ttcttgcaca gctttatgtg catcctgaat taaggttttt ggatcataaa
   678301 tatcaatatc agcaggttct ccatcagtta aaacaagcat taatttttta tcactttgct
   678361 gcaagtctaa ataatgtgca ccatggcgaa tagcagcacc cattctagta gaaaattcag
   678421 cccttaaatc agctaaacgt gcctttactg tatcatccca atgctcacca tagcctttga
   678481 tatgataata catgaccttc tgtctggtat tagaattaaa cccagaaata gaaaaattat
   678541 cacccaactg ttctaccgcc caagccaaca aagacactgc ctcttgtgat agttctaaaa
   678601 tagtctgtcc aaatttccca acaactttat ttaatgactc cgataaatct aacaacaata
   678661 aaactgatac actgcgagaa tcatgttcaa aatcaacatt aattctggta tcaggctgag
   678721 aaccattttt aatatcaatt acactgcgta atgcaatatc aaggtctaac tcagcaccct
   678781 cttcttgata acgaagacgt ttcttatttt gtggtttaag caaatctaat acttttttca
   678841 gctgtttaac caaagctgag tgcttgtcaa gaattctatc aatctttgat gcatcactat
   678901 gcgaatgtaa tcgttcatat acagccaccc aatctggttt ataagtttca taagaataat
   678961 cccattcgtc ataataatgc ggaggtatta cttcaacttg atcttcgtcc tcctcttcag
   679021 attttttttg atgttcaaaa atattatctt cttcatcaaa cttttcaata aacaaccaca
   679081 ttgaacggtt atcatctcga taagtcactt cagtattttc aaaatacata ttagctaacg
   679141 catctgaagc acttcttgtt ttaattaaat attttaatcc aagatttaaa ctatctgatg
   679201 tacttgtttt ccctgtgttc attaatgtct taaatttttc aacataatct aagagaattt
   679261 tattcttata atggtgatta tcatcaagta aagcgtatgt aagcataata gcacgatgtc
   679321 gcaagcaaga ttgatactta tcatcacaat caaactcatc tactattgga attaagttta
   679381 accataaatt ttttaaacca ggatactctt gcatagctaa atattcgaca cgagcatctt
   679441 caaaaatttc agtaaaaaat cgttgctgcg gtgaaacatt atcagcaata atcttagtgg
   679501 taaattgatg atgtgcaatc aaatgtgcca ttaaagccat ataacgcttg caagcattaa
   679561 caccgttaaa taattcataa atatctggca gacgaataat attatcttct aaataaggac
   679621 gaaagtgttc taatttttca aaatctggag aatacggtgc atacataaat tctgttttcc
   679681 agagtgcacg ctgaaataaa ttaattttcc gctcaacatc aataaacaac aaaccctttc
   679741 tttgccgttg aaatacggct tttgaatcag cacttaataa tgaaaaatat tcctcttgtc
   679801 gtttaggatg gtcttgaaaa tatcttaaac cataattaat ccacttataa ataccttcaa
   679861 attctaattg ttccaacaac aaacgcatat tagcaagcat agataataat gatggagaag
   679921 cgtgcgtatc atgaatacca tgtattgaaa atgtagtttt attcaaatga tattcaatta
   679981 gattcaagta ctcatcaagt tgatcattat ttgtatgttc aataacatca ataaaactgt
   680041 ttaaaaacgg tttaactgca tctttattag gtgtcctaga tattttttga taagcaaaat
   680101 ctacaatttt ttgaatacta ccatcaccat aaaattcacc tatccaaggc atggttttta
   680161 aaaaaacaat agataaagta tcgccttgtc caatttttgc taaaagttca gcacctttat
   680221 aatactcaat taaaccttgt tctgaaagtc ttttggcagc ttgttcaata ttttcaacaa
   680281 atactccttg aatcgtatta aaagcacaat ttaaaggttt atactgactt acttcaggca
   680341 tactattaag taatttttag tcaaaaatag catcaattgc actacccata gtggtacgaa
   680401 tttctacatc atcagtgatt gggcatacta atgccatatt acaagcatct tttactccaa
   680461 cacctgaagc aatcaatgta cctgcataat taagcaaacg agttgatgca ccttcatcaa
   680521 taccatgtcc tactaaatta cgagtgacct gtgcaagttt gactaactta gttgcaatat
   680581 caccaccaac accagactct ctaacaacaa tactggtttc taactcagcc gatacataat
   680641 caaaatccat accagtaaaa cgttgcttag ttgattgttt aaggtctttc ataagtgatt
   680701 gataagctgg gttatatgaa attaccaatt ggaagtcaga atgtgctttt acaagctcgc
   680761 cttttttatc taacattaac tcacgtctat ggtcagtaag agaatgaata acaaccatcg
   680821 tatcttggcg tgcttctaca atttcatcaa gataacaaat tgcaccatga cgtgctgcta
   680881 atgttaacgg accatctacc caacgagtgc cattggtatc tagtaaaaaa cgaccaatca
   680941 agtctgaagc agtaatatct tcattacaag atactgtaat aataggcttg tctaatttat
   681001 aggccatata ttcaataaaa cgagactttc cacaacctgt tggtcctttg atcattactg
   681061 gtaatcctaa attatatgct gcagtatata attctacttc agttgattgg gctttataaa
   681121 aaggctctaa tataatttta aattggttga tatcgaaatt tgacataact ctatcctaaa
   681181 tgtatctttt ttaaatttta taaaaaagcc tctgcatgta gcagaggctt tcattaacta
   681241 tttactacaa actttacttg tgaacgccta atttatctct ccaaccagga tataaagaat
   681301 cggcatcccc tggaaaagat tcaaatgcac gagcaaattc attattatct ctagcaaact
   681361 caattggatc agctttagcc atccaacaat catatgcttg acgtaatgac ttagcacccg
   681421 ctgaaggcga atcaatatga ccataagaac caccaccaga agtgttaatt acgttaccat
   681481 gaccaaggtt ttcaaagaaa ccaggaagac gtaacgcatt cataccacca gaaataattg
   681541 gtgttgttgg cttcatacca aaccactctt gatgataaac tggaccatca gcgctatctc
   681601 gctcaatcat gtatgcaatg tttctatcat cagcaccacc ttccatctta ccataaccca
   681661 ttgtacccac atgaatacca gatgcaccca taaggcgaga aagtttagca agaaccagtg
   681721 ccgtataacc acgaactgaa cttggagatg taatcgcacc atgaccagct ctatgataat
   681781 gtaggtactg accggggaag ttacgacgtg cagtagtaac cataccacaa ccacccacat
   681841 aaccatcaac taaaaaagca acatgatgcg cattctcgcc aaatgcttct aaaatatatt
   681901 caccacgagc aatcatttca tgatagtcat cagcagtaat attagcagag aaaattttag
   681961 cttcacccgt ttcgtcttgt gcacgcttca tagcatcaga aactaaaggc attacatcct
   682021 tcatacgtgc ataaacttgg ttaccttgag gttcatcatt cttaataaag tcaccaccta
   682081 accagaattg atatgctgct tcagcaaaag gctgaggacg taatcccaac ttaggcttaa
   682141 taatcgtacc agcgatataa ccaccatttt tacgatcacg gcccaataga ttccataaat
   682201 ctgtaatatc aacagaggga ccgtcaaaaa tatctaacat ttgcttagga acgtggaaat
   682261 caatcatttg cgcgcatttc acatcaccca taccttggtt attaccaatg gcaagtgtta
   682321 ggaaagatac aaccattgca cgaccgtcaa ttaaattacg atcgaataag ccacatggat
   682381 aggcaatctt cataatacct ttaacttcat caatctcata aaccatagca tctaaatctt
   682441 tagtaaaatc atctgtagtt gatacttcaa catttgtacc agtagatgat tccgctgcaa
   682501 agtgagcagc agtttctaaa taaccaccaa aattaggcat tatgttcatt gtgtaggcaa
   682561 caagaatatg cccgccttca gctaatagcg tatcttcgtc taatgacaaa tctgcatatc
   682621 tatttgattg atccataatg gactcctatt tattaaataa acgttcatga tacaagacac
   682681 tatcaataat gtaaaataat atttatttat gattttatac aaatatatct taacgatatg
   682741 atcaacttta cattaaaaca gctatacagc tttgaagcag taatccgtct atctagtttt
   682801 accaaagcca gcaaagaact taatattact caacctgctg tgtatatgca aattcaacaa
   682861 ctacaaaaaa atattggctc tgatttagtt aatattaaag gcaaaagcat tcatcccact
   682921 tttattggaa ataaactata tcaaacttgc ttaaaggtca ttaataagct agaacgaacc
   682981 aaatctgata ttgagaaaac actaaatcca aactctggac acctataaat tgatgttatc
   683041 agcacaacca aactcattca cttagtcatg tcttaataaa atttaaacag aaatatacca
   683101 agagagtttt tcacttagaa gtaactaatc ataaattact acttgaaaaa ctaagtaaca
   683161 attaacaaca aaactcttta tggagaatcc acatctctat tgcttatcct aaaaatattc
   683221 ccccattatt cattattggt atatggtaca aaataataat gacacactct cactcattgt
   683281 aaaatatttt aaaacgttta tcattaaaaa taattaaaaa caataacttt ttaaaaaaat
   683341 cgctaccaaa ataagtaata tcaacaatgc ttgtataaat acaatggttt tattatggat
   683401 aattaatacc caggtcttcc atatgatatt gcaaaccttt tactagcgta attttttcaa
   683461 tttattatat ctaatatggg acatgggttg ctctacattc aataattgaa ttttcgttac
   683521 gctagtaaca ttaagaacaa gttacaccaa ttaacttaac cccatattat tcagcttaca
   683581 catatggata tgaaattaaa aatctataaa cactcatact aatttaggtt cgatatgctg
   683641 aattaatttt tatataatca taagaaagat cagttgtcca tacactttct gttaattcac
   683701 ctttgccaat ctcaatagta atgacaattt cagatttctt catttgtgcc tcaccttgag
   683761 cttcggtata ataaacattc aactctccag ctttaatcaa acaaatctta cctaaataaa
   683821 tactcacatc ttcaattctc aaatacttga tattagcacg ccctactgct gctaaaattc
   683881 tcccccaatt tgcatcagaa gcaaataaag cagttttaac caaaggtgaa tgcgcaaccg
   683941 tataagccac ctcaagacaa tccttaacac ttattccacc cttaacacac acttcaacga
   684001 acttagttgc accttcacca tccttaataa ttttatgtgc taatatctta gttacagtat
   684061 ttagcgattg ttggaacttt tccatacaat cattaatttt aatactagaa acaccagtcg
   684121 cacttaatgt acacgcatca ttagtagaag tatcgccatc tatagtaata cgattaaaag
   684181 attgattcac tgcctgagtt aagcaatttt gtagttcaga ttgagtggct tcaatatcag
   684241 taaaaataaa actaagcatg gttgccatat caggacgaat catgcctgaa cctttagcaa
   684301 aaccagtaat agtaatcaaa ttatcaccta ttttgaattg tttagagtac accttgtcaa
   684361 ctaaatcagt cgtcataata gcttgtgcta cttgggaaaa gttatctatt gccaaattag
   684421 aaactaatgt agatatatta ttctcaaaac aagccatagg caacaactga ccaattaccc
   684481 ctgttgaaaa tggcaacact tgttcagcct taatatctag ctcttttgcc accaagtcac
   684541 aaactttata agtattttta agtcctacca aacctgtacc tgcattagca ttaccactat
   684601 taataaccaa tgctttaata gcatgattaa gatgattctt tgctactaat acaggcgcag
   684661 cgcaaaatat attttttgta aaaacagctg cagtttgtgt gccttttttt aaaaaaataa
   684721 tagacaaatc tagcttttta gtatctttaa tgcttaaatt ttctgaaaaa ttttgcgcat
   684781 gcttaatacc agaattaatt gctgcgcaag taataccgtt aatatttaat atattatcca
   684841 tatcatgata aaaatcctag tcaattaaaa cttgtttctt agtgctatta aaaatctata
   684901 gtacagtaac ataataaatt attgcttaat acttcatttt tagaaatttt taagacttct
   684961 tgtctaaata ctgaaaaata atcattagta cggaaccaaa tagaaccatt ataagggctg
   685021 gtatagcggc tcgttcaaat aaaccttcag cacttaattc atacacttga attgccaatg
   685081 tatcccagcc aaatggacgc aataaatagg tagctggcaa ttctttcatt acatcaaccg
   685141 caactaacaa accacctgcc aaaatacctg gagtcatcat gggtaagtat atttgccaaa
   685201 taagtcgtaa acgtgacaca ccaagtaaac gtgcactttg agtgaacata ggcttaattt
   685261 gttcagcact ggctttaatt gaattatagc caattgccat aaaacgagat atataagaaa
   685321 ataataataa agcaatggaa ccaaaaataa tctgattaat actttgtcca ccaaaatata
   685381 tactgactgc tgacacttgg ttaataccat ataatagtcc aactgccata attgaacctg
   685441 gtaatgcata gcctaatgtt gctatattaa tcacactttt aagccaagaa ctattctttt
   685501 tacaatgatt gggcaatgct aatatagtag caatactaac cgttattaaa gtagctgata
   685561 cagttagaac taaagttgag atgatcaaat cagtatacct aacattcaac tccttacttg
   685621 agtatgccca accccaaatt atcaattgta acataggcat ggcaaaagca agcataaaca
   685681 cgctaaatat aaaaatactg attaaccaac ccataatacc aaaagcacga taaggctttt
   685741 tattaaccac atcgcttgaa taatattttg cttgtccacg tgcttttttt tcaaaataaa
   685801 tcaaaaaaaa tgccactaac actaataatg atgccaattg tgctgccact tcaatagaac
   685861 gaaaatcacc ccaagcagaa taaattgccg tagtaaacgt atcaaaatta aacaaactaa
   685921 ccacaccaaa atcagccaat atttccatta gtgttactaa taatccagct gctgctgctg
   685981 ggcgtgctag aggcaaagat atcttaaaaa acgtacgcaa aggactagta cctaacaaac
   686041 gaccagcttc gattatatta accttttgac gtttaaatga ggctcgtgcc atcatgtata
   686101 cataaggata aaataccaat acaaaagtca aaataattgc ccaagatccg gcacggatat
   686161 caaaccctga taaacctagt acttcacgca tccaaacttg tacataacca gaatagtcaa
   686221 atacacctaa atatacaaaa gctaatacat atgcaggaac agcaaaaggc aaaaataacg
   686281 cccattctaa ccactgtcta ccagggaatt caaccattac cactaaatat gctaaaattg
   686341 tacctaaaaa agtaacaccc acccctacac caataagtaa aactacagta gcactgatta
   686401 aatttggtaa taaaatagta gaaaaatgcg cccacagttc acgttctgga aagaaccacg
   686461 acacagctac aacaaaaatt ggcatagcta ccaataatgc taaaacactg atccaaactt
   686521 ttgatttaag gcaatttttt tccaaaatac tctttttaat ttttaaaaac tattttaaaa
   686581 actcaagact gttaaagtct gggtttcttg ctactaaaat agaaacttat cgatagcctt
   686641 ttgtttgcat gagcttcact gcatcagctt gtaatatacc tgtttgttct aaattcattt
   686701 tatcttgctt gaatgatccc caactcgata ccacttcatc tgaaataaca ttctgattag
   686761 ctggatattc tttattaagt gatgcataaa tagcttgtgc tttagcattt gataaccatt
   686821 ctaataattt aatagcaccc ttgacattag tagcatattt tgtaacacca gcacctgata
   686881 tatttacatg cacacctgtg gtatcttgat ttgcccaaaa taacttcaat ggtacattag
   686941 gatttttagt aattaaacga gcaaaataat aagtatttac caaaccaata tcacattgac
   687001 ctgaaataat tgcattcata atatgagaat ctttagcatt aggtgtagct gccaaattat
   687061 tcacccaacc actaataata tcgctcgctt tatttattcc atgatgataa atcatcgatg
   687121 ccactaatga cttagtataa atttttttac tagttcttaa acacaatcta cctgcccatt
   687181 ttgtatctgc taaattctca taagtagata gatcgactgg attaacacgc tcagtgctat
   687241 aaacaatggt tcttgcacgc actgatagtc ctgtccacaa gcctttagaa tctcttaaat
   687301 ggcttggaat gttgttttct aacgtttgtg tttgtactgc ttgaaataaa tcttgcgtag
   687361 cagcatacca aagattacct gcatctacag tcataaacat atcagcatta gtgtttttac
   687421 cttctaattt caaacgctca attaatgcac cacctttgcc tgttaagtac gtaacttgaa
   687481 tgcctgtatc tcttgtaaaa gattcaaata aaggtttaat taaatgttct tttctagagc
   687541 tgtatacagt gactaaatct tcacttcttg ctcgtgctat accaacacta gttactacca
   687601 gtaacaatac tatcaacgct ggtactatcc gtatttttat attcatcctt attttctcct
   687661 tataaaaaaa ctgactaagg ttatataatt gatgcatatt atcaattaat agtcaatttc
   687721 ttatttttaa ttactcctac tttatcagca aaaatagtcg cctcatattt gtcatgtgtt
   687781 actagaattg aagtgatgtt agttttcttt aaaatgtctc tgacttgtaa tactaattgt
   687841 tcttgatggt tcttatctag actagaaaat ggctcatcca ataataataa ttttggtgag
   687901 ggggctaatg cacgagctaa ggcaacacgc tgttgctctc cacctgaaag ctggtgtgga
   687961 tattttctct caacaccttt taaaccaatc atcaaaagca attcttcaac cttagttttc
   688021 tgtttgctgt ttgataaatt ataaatacca aaagaaatat ttttttttac attcatatgc
   688081 ggaaataacg cataatcttg aaacaccatt cctatttctc ttaattctgg tggtacatta
   688141 tgtgtaccat tgttagataa ttgtttacca tttaaaatta cctgaccact ttgcgcctca
   688201 tcaagtccag aaataaacct aagtactgaa ctttttccac taccactatc acccaataag
   688261 gcaaaaatat cacctgtagc aagacttaaa tcaaaatcat ttaaaatttg agtggcttga
   688321 taggaaattg ataaatggtt aactaataac atttaataat aaaaatgata atgattccta
   688381 tcattatata agatatatta atgataatat catattaact aaatttcgca aaaagacctt
   688441 aatggaattc ttttgttatt atcaatatca gtcataacag tatcaaaatc ctctggttct
   688501 accaccaaaa attgtcccat cattcctgcg tcttcatgtt ccaatatatg acaatgatac
   688561 atataagggt attgagtatc tgcgtagtga tcaaatttag caactactct tacggtttct
   688621 tctggcataa gtaatacggt atctttccaa ccacgttcat tttcatttgg cagggttgga
   688681 tctgaaccat ctccttgttc tctatcaaga atttgaaatt gaatatcatg aatatgaaaa
   688741 gggtgagtag tatgtgcacc gttggtaatt cgccaaattt caacatcacc ttttttaacc
   688801 acttcattaa tcacattcat gtccatttga acaccattaa ttaaatgtaa catatgctca
   688861 ccttcaagta caataccatt aataacttta aacatggaag tgaaaactcg tctattgatt
   688921 ttaaaaccac tcataactgt taatccaaaa ttcctagttt taatagcatc tgactctttt
   688981 aatcggacta ttttagtgag tttattagga atttttctaa caacattagt actagttgat
   689041 ttattaacgt aaatactcat aacatcaaaa ttaattttat ctaacgtatc taccgaatcc
   689101 gataaacgac ctgtaccacc tactttaaat ggtccaccaa actgatgacc attaagtttt
   689161 tgtttatcat aatattcagc actaaaactc ttgaaccgta aaattgtatt cttgctatta
   689221 ttcaaatcaa gcaaaatttc tactcgttct gcaggaccta gtaataccct agtaagtgaa
   689281 accggttttt ctaaaaaacc accgtcacta gcaatttgat aaaactgaat atctccttca
   689341 aaacctaaat tataaattct tgcattagag ccattgagta ttcttagtct aatcacttga
   689401 gcaggtacat ttaaaatagg cacaggttta ccatttacca aaattgtata acccttcatg
   689461 ccgcctgatt tatcaaaatc acctttattt aaataaagca attgggcttt ttcatcaaat
   689521 cgcctatctt gaatcaccac aggtaaatca tcaacgccat aagttttagg aatatctaat
   689581 aatctagaag tttcatcatc aattaagaaa aaacctgcca tacctttata cacttgttca
   689641 cctgtataac cctcaagatg agggtgatac cattgagttg aagctaattg attaatacgc
   689701 caactaggtt tccatgtttt gttaggtgga ataatttgat acggaccacc atcttcttta
   689761 gccggcaaat gcaatccatg aaaatgtaca gtggtattaa ctgataaata attggttatt
   689821 tcaaaaccca cattatccat attatccacc cgaatagttg gacctaaaat actatcacca
   689881 taacctaata cgcatgttaa cttaccttta aaaatttcta ttgtattgtg attgattgaa
   689941 aatttaaata ttcttttacc gttaacaatt gtaggttcaa taagtggtgg aacaataaaa
   690001 gatctatctg cataatcagg ataaataaat ttatcagaac gcttatcact acaacccact
   690061 actagtatac tactagataa aatagatgtt ttaataaaat ctctacgttt cataactatt
   690121 ctctttttag tctttagaac caaaataatc tcatacaata tgacataaaa ttcttacttt
   690181 tttatttgtt tataggtaac aataaaaggg aaaaataaca aatctttcaa actttgaaag
   690241 tttttcatct gcgtcttttc taaaccaaat ttaatattag ttacgttttt tgaaagaatt
   690301 aatgtgccaa ataaatagtc ccaaactgac aaaaaaccac caaaattagt attcatatag
   690361 ttcttagaat gatgaatttg atgttgtaga ggagagatta aaaatagctc aaccacattt
   690421 ccaaaaccta acttgatatg agaatgtcta agattagacc ctaataatga aaatataaaa
   690481 acaaacaaat taacacctaa gatatcataa atactcacca aactaccaaa taaaaataca
   690541 aaaacacctg tcacaaaacc gatacttaga gaatagcgaa aaccaaacaa caagaattca
   690601 ataggatgta ctcgataaaa cgtcagtgga tttaaaactt tagcactatg gtgtacttta
   690661 tgaaacaccc ataaccatgg tacaaagtgt aataaacgat gtaaccaata acgggtaaaa
   690721 tcatttaaaa taaacaaaat aagtgtaaat agcaccatta cttgtgtata agataaagtt
   690781 tctattctca caaaaccata ttgatttaac aagacaatat taacaaacaa tgcaacttct
   690841 ttagtactta ttatcactgg taatataatc ataactctaa agaatacaga gaaaataaaa
   690901 taactataat ccaataaact agaaggatgc agccaaagtt tttttgataa aacaatacgt
   690961 tgctgttttg gatgaaactt taaaaaaaca aatgtaatca tcaacgaact tagtaaaaat
   691021 aaccaataaa ttcgcctatg aggatccatt aagtattcaa acggattaat ctccatcagc
   691081 atctaacact ttagagacaa accccaattt atccattaaa gaaatgtaat aggctttcat
   691141 aagcctatta gttgattgat ataaacgttt acccttgtcg ttaataaaat caaactcgga
   691201 catattattc gcattagcaa ttgaatcatt taatgcacta atagcctggt cgatctcttt
   691261 tcttgcttta aattgacgtg atatatcacc aagatcttga taatctggtg aattaataat
   691321 ctgagcttgt gtttcaagaa tagctttaat agcattgaca ctattgccac tagttgcata
   691381 ctctgctcta taattgttcg gtttattctt aaatttttta ctcaaaccag ctacatcacc
   691441 aacacgccac tctttaagtt tataggtacc agcaattaaa gtatttaaca gaattgcact
   691501 agcatattgc tcattttcaa ggaattttga ctgatacatt ttataaccat ctaaaatttc
   691561 tgacaaatag cttttgattg acttggcaat tattaacgcc atatttttaa ccctctgatg
   691621 agacaaatct tttgtaaaaa gaacatattc caaagcatta atagttttgt gtgaatactt
   691681 atacatagca ttaaatagct catcattact attaataatt aaatctaatt gaggtttaat
   691741 ctcctcatta tttccatgaa atatatcaat gtatcttggt gtatctaaat aatcctcatt
   691801 taaatcaccc aaaaaataag tagtttcaac ttttttccaa cttgaaacta agttaccgaa
   691861 ttgcattcta attcttgtag aattagcttg attaatatta tcaattaata aatcaacact
   691921 tttaatggct aatataatat tgacaataat aacttggtta aagaactttt caccaactgc
   691981 atttacaaca atcgatataa aaaaaataat aacaaccaag tatctcatca acttacccta
   692041 tatctcattc aaaaattgca atattttacc tctactacta acaggtaaat tcataaacaa
   692101 agttttagac ctctcagcct caccaccatg ccaaataatt gcctgttcga ggttgcgtgc
   692161 acgaccatca tgcaaaaaat tcttattatc tttaagtatt aaagaaaccc tgcccaatct
   692221 ccataatgga ggggtacgcc attcattacc taaagcatca aattctgaac gatcatctgc
   692281 taaatccttt cccatatcat gtaatagaaa atcactatat ggatatatag taatattagg
   692341 caatgaataa cttggaacat gacattttga acatcctatt tcagagaata gtctttgtcc
   692401 ttgatattgg ctaataatag attttggcag tttcaaatgt gtcaaataat aactaatagc
   692461 atttaatctt tgtgctgtta gctcatgttt ttctccatct tttgaggaat taatacattc
   692521 aacttgtatt aatgtgcacg actgatgttc gtaaatagga ttagttaaac ccatatcatt
   692581 aacagcagca ttggctgatt gatactttac tgttggtgca gaagctttcc aagcataacg
   692641 accaatctca attttcttag tctgctctga ccaaacccta ttagctttac cagaaatacc
   692701 atcatgatta gcatcattaa tatcttcatt agctagaatc tgttcatcag taatttgttc
   692761 caataaaccc aaacccacaa gtgctggtgc aattctagca gaaataattg tgttaggaag
   692821 taaatcacca taacctaatt tctctaattt aactattggt tgttgcaaaa tgatgatagt
   692881 attatcggaa taatgaatat ttttagttga ataatgtacc aaggacttgg cttcaaaagg
   692941 tacaccagga actccattaa tgctaatttg aacaccataa tttggctcag gaatagaacc
   693001 aaatttagct atcattcctt gatgctcatc agtatcattt aaaggtatgg ataagcgtat
   693061 tacgtgtgac ttatcaacga tattatttac ttcaaatact tttccacgac cattttttac
   693121 atgacaatta acacaagtat tagcactaaa taatggacct aatccatcac gtgctgttgt
   693181 tgaactagga gcttctaccc aaggaatacg aaaaaaactc tttcccaaaa taaacttatc
   693241 caatttatca ttacttaaat taggctgaac ttgcgtaaaa gactgactta actcgtaggt
   693301 tgataaatta ctaaaatcat tagcgaaaac cctttccatt agactaataa caagaattaa
   693361 tatgattaaa gccgctgaat atttatagtt taatttcctc aacatccatt atatttccaa
   693421 ctgttaaatc aataccattt gattttgcta cataaatcat ttgatcacca atggctctta
   693481 actcattttt aagtattttg atttgcctag cttgagagtc attcggatga atttgataat
   693541 caaaatgacg gcttacttgt gccaatgtat tcatttgatt aattttagta tttactgatg
   693601 caattaaacc cattaactta gttttatctt tcatagcatc aataagtgct acaccatagt
   693661 caaaaccatt ataagtaccg aacaacaaat tcttaaaacc ttgaaaattt tgcgttatat
   693721 cacgatgtgt attatcagaa aaacaactat gctcatcttc ttcagatggc gttagtactg
   693781 ccattgcaat acgctcatta gcaagttcag atttaataaa aatacctaac ccagaaaaaa
   693841 tttgcttaag tgccaccttt acattaatat tcttagtcac atcagaattt tgacccaata
   693901 atgctgcttt ataattagta ctatcgccat ctgcccaagc cgaagttatt gactctaaat
   693961 cagaaataat tagactcgct gcggcattta aatattgttt acgacgatca gcatttacat
   694021 taatcgtata atcagcaagt ggtctctgac ctgctaacaa tgcaccatga gttacactat
   694081 cttttataaa attagtataa tcctgatctt gaccccataa taaaaactca ataacgtgat
   694141 aaccagttgt aacattagca ttgccaccat tttcattaag cgctactaac acatcagaag
   694201 taattatact tacatcaatc actaaaggat tttccccacc tggattaaat atatctgggg
   694261 tatcaataat attacctgat gtttttctac ccttagcatt ggttgtataa tcaatcatat
   694321 tttcatctaa tggccaagca tttaatcgcc cttctggtgc accataagat gtatgccaac
   694381 cttcctctgc atcaataggc ccattagaca atctaaacgc ttcagtttga ctataagatt
   694441 cacgagcgtt tagccatgcc gctttagcat ttcccattgt ttctattgta ggattaattg
   694501 taaaatcttt caattttatt cctaattttt tagcatcatt caaggcatcc gtgtagttta
   694561 tagttgcaat atttgcataa gtgattaaca acggattaat ctcatttcca ctcaagaata
   694621 cacttgcagc agaaattact attaccactg tcaaaacaaa cgaaatcatc aatttttttg
   694681 tactgtcatg catatttctc cttacactta taaaaattct atagttgcta ttattaatac
   694741 taaaaagcga tttataaact attaattgat tttttatccg ttcattttat tattttcaaa
   694801 aagataatta catcttataa ctaatcaaaa gctataagct aaactcgaca accattcaac
   694861 ctaaattaaa ccataaacga taaggattag aactaccata accctttata tcatttttaa
   694921 aataattcac accaatacta ataatatatc aactgctgta tctgtaataa tattcatata
   694981 cttaatacta gttatcctat atattgttaa ttagaaatat ctacagaact acttctgcag
   695041 atttgatacc tgcctgtatt aatcttaatt caccttcttt tattttatta aaaatagtta
   695101 atttcttcaa gttagtaaat gatatcagtt attatttgca tttataataa aatataaaaa
   695161 ttatgtaata tatcattttc ttagctattg agaaaaaaat aaaacctctt aaacactcag
   695221 ctataccatt aactaaatta attttcatag atctagcatt taaatttgat tttatgattg
   695281 atattattaa cagcacattt attacaaaat caaatttatc ttaaaattat acaaacactc
   695341 ttaaatcata atattatata agttctactt tgatttactt atatgctaca cagaaaagaa
   695401 agtatgaata aattactatc acccctagat atatcttaat aattgcatat tataaaaata
   695461 taacataaaa taaaatagtc atcattcatc tttttaccac tttggattta aacaaacgca
   695521 ctcaagccag tcaaaaagtt acacttgtag gtatcactgt tgatttttta ttggcgatat
   695581 tgaaagttat tacaggttct attggaaatt ctggcgcttt aattgcagat ggtgcccact
   695641 cattttctga cttattatct gatggattag ttctatatgc tactaaacat tcaacccttg
   695701 atgccgacga agagcaccct tatgggcata atcgatttga aacagttgct attctaggtc
   695761 ttgcaattat tttaaccatt gttggtttag gtattatttt agatgcaatg attaaattat
   695821 ctaaccctat tacactttca cacagtacgt tacttttaaa tattactatc ttatcaattt
   695881 tttctaaaga agctttatac tggtatactc taaaagtagc caatgattat aaatctgact
   695941 tattaaaagc caatgcttgg catcatcgtt cagatgcatt atcttcaatt gtagtactaa
   696001 tcggcattct tggcagttta aatgattatc catatttaga tagtattgca gctatcgttg
   696061 tgggtgtcat gattatttat attgcttgga aattaggtct aaatgcaact aaagaactag
   696121 tagacacctc tattgatgca caacaagtag cagaattaaa gcacgcacta ggacaaatta
   696181 atgatgttaa tagtgttcat tctctacgta ctcgcaaaat tggacacact atttcttgtg
   696241 atgtgcacat acaagttgat ccttttttaa gtgttagcga ggggcatatt atcagtatta
   696301 gcgttgaacg tgtagccaaa aaatgcttaa aaaacttaaa cgatgtgaca gttcatattg
   696361 atgtagaaga tgatgaaact aattctcctt acaaagcatt accagaacgt tcagaagcgt
   696421 taggaattct aactaaagcc ctatttaata ataaatatag cagtgaaatt agtcgtattc
   696481 aattacatta tttagaaagt aaaattcatg tagattttta cttaccactt aaatgtctcc
   696541 aaactgacaa tactgctgat aaaatactaa ctaagttaca agagactgtt aacaatcttg
   696601 ataattttgg aaagattaag gtttatttta gccaaaatta aaaaacaaca aaaagcatac
   696661 taatagcact taataatgta tctattacat ttatctggag tatatcttat taagtcttaa
   696721 taatctcttc ttgcatcata aataatgcct gttcttttaa cagcgtatta tttctcccac
   696781 aatagtcttt taattagatt agaaaccata ttactacatt aaaatttaag cttattaggc
   696841 tcaattaaac cgcaatctgt tactcttgaa ccaaaatcaa ctcctaaaat tccattaaaa
   696901 aatatttaat aatttttcta ggtttatcaa acacatatta cacccttatg atatactttt
   696961 atttttctaa attttaagga ttaaacaaat ggcagtatta gaactaaatc taagtaattt
   697021 tgatgaaacc attcaaagta atgacattgt tatactagac ttttgggctc catggtgtgg
   697081 tccttgcaaa caatttgcac ctatttatga tgaagtttct aacaaagtag ataatgttat
   697141 ttttgctaaa ataaacaccg aagatgaaca aaaactagca agtaattttc aaattcgatc
   697201 cattcctact ctaatgattt tcagagaaca aattgaagtc ttctctcaac caggagcaat
   697261 gtcaggttct aatttagaag atgttattac taaagccaaa gcatttgata tgaacgaaat
   697321 gcgtaaagaa attaaaaaga aaaaataatt attattataa ctttaaataa tttttttcac
   697381 taaatccaac catgatatca tcacctatta tcaatattgg gcgtttgata agtgttgggt
   697441 ttttcagtac taaatctaaa gtaatattac ctttttcttc atcatttaaa tttcgataag
   697501 tagtagaacg cttattaata agattttccc aagtgacttt atctacaaat gtttgtaact
   697561 tagttttatc aatcggatta tcacgaaaat caataaattc aaaatcaacc tgatgattaa
   697621 tgaagaattt ttttgctttt ttaatggtat cgcaattttt aatcccatac attttaatca
   697681 ttgaactacc tcattataaa attctaaaat ttctttatta tcatcatcaa taatgatacg
   697741 tacgcctttg atcaaataat accaatacga cacactctga ctaaccagct ccactctact
   697801 aggttcacca aatagattaa taattatttc ttttgataaa tctactttag gtataagggt
   697861 taatgacttg atttttagat ctaacattga tattttagcc atcaaattaa acgttgtttt
   697921 cctaacacct gaagacataa ctcttaattc tttaatgttg ttatttaaat atttagtgtc
   697981 tttttggtca aatattaaat ttaaaataac accaacacta ataccaccta ctttggtgtt
   698041 agaaaaaaat acttctaatt ccggttcctt actctcactt ccaaacatag caatctcagc
   698101 ctcagagcca aataaatgca ttgcatcaat aagactacta tggcccatgg ttaaattaaa
   698161 tacaaccgta ttaccttgac tattgataaa actttgccac ggcatagatt gattttgtgg
   698221 tatttgtatg ttacgagtca ataggtaaaa tagagtaaat attactactg ctaataataa
   698281 tgttattgat attattttac tttctatcat taattatcgc ttaaataggg gtttgttagc
   698341 tttagaacgt aaccaattaa gtgttttaaa ggttaagtta tgattgatta atttaagttc
   698401 tagttgtcgc ttacctggaa attccattaa aaataaacct aataaaattg atattaatcc
   698461 ttgacctggc gtcactaaca taataatacc aacaattaat aatataaaac cagttagtgt
   698521 cttaagtatc aatttaatca aattaaaagg tcttcttatt tttaatttct tttctgagtt
   698581 ttttagaaaa taatttgatg gcattagccc taataaataa ggtattaaca ataaactaat
   698641 gataaaaatc actccagaaa ttatacccat aattactagt atatcgtcta attgatttat
   698701 aagtactact atactatcta ctaacataat aataaaaata tcacagactc attattggtt
   698761 aaagatactt gtatattagc accaaaaata ccactaataa ttaactctta ttttagtcaa
   698821 aaaataatca aacaatactt tagtttgctc tgataactta gtggtaaaaa accaactctt
   698881 atgcctaaat tagtattagc taatagaatc aattgaaaaa caaccaatac ctcgcccaac
   698941 atatctttaa tcaatagact catccttttg attcgcgtca taaaatacct aatataataa
   699001 caattatata atcattttct ctgtttttac ttgttaatta tatttttcaa tatcaataaa
   699061 actaacattc cttgattgat tttttccata attcactatt tactttaact ttagcattcg
   699121 ttacgtgtta aattaaagtt ttcattatta aacaagatat gaaatatcag caactgacaa
   699181 aaataaagat ctaacccagt taattagatt taaacgcgct tgtcttaact caacatcatc
   699241 agtattaacc ataactttat caaaaaactc atcgatcata tccttaaggg caataagttc
   699301 tttcatattt tttgtgtagt taatagaatt agaaatgcgt ttagcaagta tttttgttgc
   699361 cttaaatagt gttttttccg ctgtttctat caaaactgaa tcatcaactt taattgataa
   699421 gtccgagcaa ttcttcaata tattagaaat acgtttattt atttcaatca gattttctaa
   699481 ttcttgattg ttagtaaatg tattaagcgc tctaatacgt agatgaaaat cataaggcga
   699541 ttctggacac actgccaaaa ctgcatcaaa gacctgcata ctgacctcat gcttcttgta
   699601 ataagaacgc aaacgctcca tcataaattg ataaatatcg ttagctttat tagtatttac
   699661 aacagataaa tgagcattta atgattcact aatcagttct ttaagattaa tatgaaattt
   699721 tgactccaat ataatcctta ataaacctaa tgccatcctt ctaagtgcat acggatcttt
   699781 agagccagta ggaccctggc caataccaaa aataccagta attgtatcta atttatcagc
   699841 aatcgaaact actaaacctt caattgtatt tggtaaagaa tcacctgaaa atcttggttg
   699901 ataatgttca ctaatagcca cagacactgc tttattttct ccatcattaa aagcgtaata
   699961 cccccccatt acaccttgaa gatcagcaaa ctcacctacc atatctgtaa ccaaatcact
   700021 tttacaaagt aagccagcac ggctactgtc tttaacatta gcaccaataa cgccagcaat
   700081 atatcctgaa agtatctcaa tgcgtttagc tttatcaccc atggaaccca aagatttcat
   700141 aaacaaaact tggtttaatc tatctagacg aaattcaaga gtatatgcct tatcttgtat
   700201 ccagaaaaat tctgaatcac ttaaacgaga acgaataaca cgctcattac catcaataat
   700261 aactgataaa tcactagact caatattagc aactgaaata aatgatgaca tcaaattgcc
   700321 attcatatct aacatatgaa aatatttttg atacgatttc atcacagaaa taagcacttc
   700381 ttccggaata tccaagaatt tagatgaaaa attacctgaa aagacacacg gatattcaac
   700441 caatgcacaa acttcatcaa gcaaagattc atcaataacc gctgtagcat tgttattttg
   700501 cgctacatga attatctgtt tacgaataat agccttacgc atatcaaaat caacctcaat
   700561 ttgagctttt tcaagaagag ttttttgata gtctttagca caaataatat caaaaataca
   700621 ttcatctgta aagcgtaacc ccctggttat gttgctagaa atcaaaccca taattgaagc
   700681 tggtacgaca tcagatccta acatcataat caaccaatgt actggacgta caaaatacgt
   700741 atctaaatta ctccagcgca tgggtttggc aatagggata ttctgaatag cagtattaac
   700801 aacagattca agtagatcta tcgtttttag acctatttgt tgtttggtaa agaaataata
   700861 ttgtatctta ccaaatgctt tttgcgttaa catatttcta gcgacaccac aagatttagc
   700921 aaaaccttca atagctttat caagctcact aattaatggc cctttacgtt caatagtttg
   700981 attattttgc tgaagttgaa gaccgttaac caataccgct aaacgacgag gcgtggcaaa
   701041 agactcaaca cttgaataag acaacttaag cttatcaaat tcagtggtta aattgtatgt
   701101 aagcgcattg gatagatgtt gcaagttttt cggtggaagc tcttcacatc ctagttctaa
   701161 taaaaagtct tgtgtattca taaaagtttg aatgtatgtt ttacttaaat aatttaaaat
   701221 ctaaactttc cgactaataa atcgatcatc gctctaataa catataatct gataagcaca
   701281 atataaatcg cttataagta tcaaaaataa agattaatta tgcgttaaaa gactggaaaa
   701341 attatggttt tcttattacc ctgaacacca ataaataaat acctttgcac ctctttatta
   701401 taaatatagc caaacgatat aactacagta cttccattta gccttatcta aaataatcaa
   701461 attactatct tttacaataa tctgctcaaa aaattcactt cattaaccac acctttatat
   701521 gatatatata aatttatcct gacataaatt taactttatt ttgattattt ttttgacttg
   701581 tcttaatttt gttaaattta aataactgga caaatatggc tatgctacca taaaatttag
   701641 aaaaatcgat taaatctgtt tatctaagcg aattcccact aataccatat tattttacat
   701701 caatatttta acaaatactg ctaaatcatt cgcagataaa tattatttcc caatttgggg
   701761 aataacaagt acatattatt ctgtctattg tcacaactta aaatactaat ctcttgcact
   701821 aatgtatcga tatcattaat atgcactact taaggtgcaa aaaatatctc agttttaact
   701881 ttaatctcaa attaattaat ttttccatcc ttgtgtacaa tctaaaaaat accaaacacg
   701941 catcatacca gtatcgccac ttaacataag ttccagtggt gttttatgtt taaatttttt
   702001 aaccgggcgt tttaaccaaa ttgctccata ttctttatta attggaaaag ttgtacccaa
   702061 ggattcacta actcctaaaa ttatttcagt acgttttatc aatctctcat caaaatcaaa
   702121 caatttatat aaatttttat ataaacacaa atgtctgggc ttaataaccc catacaaatc
   702181 taatagcttt agttgctcaa tatcttctaa atgccaattc tctaagattt taaacaactg
   702241 caaagtaaga tttgattgag tcttagtatc taactttaaa atatccatta attaacctta
   702301 aagtgaaaca agatttgtgc atcaaataca ctcctatcag gagcatatgg taacggagaa
   702361 gctttataaa cagcacgctc aattgaatct ttaaatgatt gtaccttgat aatattatca
   702421 atattacaag atttaaggtt aacactcttt acttgaccat ctaaatcttg caaaatctgc
   702481 acatcacaac tccaactatc tttagcgcct tgataatgcc atttttcttt tactctagat
   702541 gcgatttgat tgatatagtt aaactttagc tcatttaaaa tatcttcttg agcaatcagc
   702601 ctatcttggt cttcttcagc ctgaacttct tttttcaaaa aacgtttatt ttgttctttt
   702661 ttaaattttt tagcttcaac ttgacgtaat ttttcaatct cttgtttttt attttcagct
   702721 ttaagagctt ctctttcagc ttgttttctc ttaatttcag caataatttt ggctttcttt
   702781 tcttgtttaa tcttaatctt tagttgtttc aagcgttgct gttccttgta acgctcattc
   702841 tcaacttttt tttctgtacg ttgtagttct tcaagacgct tttctcgcct ttgtttaata
   702901 ttaattaacc gttgtttttc tttttcaatt tcagttaaat caatcatcat tgcttttggt
   702961 atttcgtcta acttaacagt ctgttttgga attcccaagc gttgagcatt tgagtatagc
   703021 aagccaatag ccaacacaac atgaagagca attgctaccc aaaaagcaat aggacattgt
   703081 ctaacaatct taggtaattt aatttcttta aagaaattaa atttcattat cttaaatctg
   703141 gagattcagt cacaatacca actttatcaa ccccattttt ttgtaaaata gacattaaag
   703201 atacaacaga accgtaatcc acttgtctat cgccacgaac aaataccttc attttcggat
   703261 agatctcaag cctagcatta acacgaccta caataacacc taatggtagt ttttcaccta
   703321 taacaacaac atcagaatcc atttcattaa gtgaattgat gaaatattta ccttgtttat
   703381 caatggtaat aatcgtaggt tgttgcgtaa aatccacgat ttttgcctca gcgaaaggta
   703441 agtcaacttc aataccttgt tcaataatag gcgtagtcat cataaaaatt accaataaca
   703501 ctaacatcac atcaatatat ggaacaatat taatttgtgc atctataaca agtctatgac
   703561 gttttagtaa ttcaatcatt ctctattttt aacttatttt tttgtctttg gaacaaaaca
   703621 aacaattgtt caacaaaaac tgaatattta ttattaatca tacctacttt agtaattaaa
   703681 cgattatagg caatagtagc aggaatagcg gaaaataaac caaatgccgt tgcaataagt
   703741 gcttcagcaa ttccaggagc aacaatagcg atagttgcct gtttaactga tgccaagcca
   703801 ataaaagaat gcataatccc ccaaaccgta ccaaataagc caatatatgg gctagatgag
   703861 gcaatcatag ctaaaatgct taagccatca tctaaataat caacttcatt attagctgta
   703921 atattcatga tacgataagc acgctcagca tttattatta actcttggct agaatctgaa
   703981 gtagtatagt taagctcctg ataacctgcg ttaaaaatac gctccattga actttgatta
   704041 gtagattctt gaaaagtttg gtatgctaat ttttctaaat caacattagt tgaaaacttt
   704101 tgataaaaaa acttaatact cttgttagta tcaatcaaga ttttcttttt tgataaaatc
   704161 agcgtccatg aataaatact catcaatact aaaataaaca tcactacttg caccacaaaa
   704221 ccagcactaa gaattaagct aaaaattgac aaaccattat ccatctattt tctccaaaat
   704281 cacactagaa atatcacaaa tatttaagac taattacact caaacaaaac atagttattt
   704341 gcgttctaaa taatacctta tttagctcta aacccattat tttttgcaaa aaaccaaaaa
   704401 ttagtacatt atgatttttt tatttcagaa taaacgatta ataaatcatt aaatttgact
   704461 agaagtcaac actcagaaca caaataattt gataataaaa ataatagctt gatgctgtat
   704521 taatcgatct tactcaaaac ctaactatcg tgaaaatttt ctacatcctc ttttaataaa
   704581 tttaagaaaa taagcataat aaaactacac cagcattaac aatattctca tatataaata
   704641 aaagtatttc acttgcttat tgattaaata aatcattcac ttttaagccg ttaattaatc
   704701 ccaaatgtgc ataagctgca tctgtaatac tacgaccacg tggtgtacgc ataataaaac
   704761 cctgttgaat caaatatggt tctaccatat cttctaaagt tccacgttct tcaccaatag
   704821 aagttgctag tgtatccaaa ccaacaggac caccagaaaa tttattcata ataatagata
   704881 gataatcacg gtctaattgt tcaagtcccg cttcatctac cttaagtatt attaatgctt
   704941 ctttggcaat atcttgatga atcatactat tggcttttac atcggcaaaa tcacgaactc
   705001 gacgtaataa ccgattagca attctaggcg ttccacgaga acgcttagcg atttctaacg
   705061 caccttttga ttcaatttga atatctaaaa tatccgccga acgttcaaca atcattttta
   705121 aatcttcaac attgtaaaac tgtaagcgtt gaataatacc aaaacgatct cgaagaggtg
   705181 aagttaacat accaacacga gtagtagcac caattaacgt aaaaggtggt aattcaagtt
   705241 gtacagaatg cgaagccaag ccttcaccca ctataatatc taatttaaaa tcttctaaag
   705301 ctggataaag ggtttcttca accacataat taaggcgatg aatttcatca ataaacaaaa
   705361 tatcataagg atcaagtttt gtcaaaattg ctgccaaatc tcctgcacgc tctaatactg
   705421 gaccagaggt tttcttaaaa cctgtggaca tttgattggc aattacattt gccaatgtag
   705481 ttttacctaa accaggagga ccataaatta aacagtgatc taatgtatcc ttacgttttt
   705541 ttgctgcttt aataaacagc atcatttgcg acttaacatc attttgccca atataattct
   705601 ctaaagaatt tggacgtata gaagttatta ccaaatcttc attattatgg tctttttcat
   705661 ctattaaaag atcttcttct atcatgctaa attacttaat tttatgctat ttttactgat
   705721 taaacttcat taattagtag tttgattttg ataggtttgg tcgtatgatt aaaatgaatc
   705781 actttcggat attgaatacc atcaataaaa ttgataacag ctaattttaa ttcgccaata
   705841 acgaatgcta tttacctcat ttttaaacaa tatatttatt agaatacaat gggtaagtac
   705901 catcctattt tactcatcat tcattgatta aaagttatca taattaactc gctattaatt
   705961 aataattttt ctaactaaac tcaatctaaa caaggccaaa ggctatactt aatatagatt
   706021 tataatcatt gtagtaaaac tcacctcaaa acctaatgtt tttgtatcat tattaatgct
   706081 cacacccaat ctatcataca ttttccaagt acttggtaga gtttgtgaaa atgctaattt
   706141 tacagattaa atttaagtac tgacaacttg ataaaaacaa ggtagaaact attatatatt
   706201 cgtttcatat aagctaccct attgtagcgt gaaacttgtc atttgggtat aattaagcat
   706261 ttattttagt tagttttgct gaatttatgt cgcaaattgc aattttaagt gtcaaccatc
   706321 aacttgcgcc tgttgaagtg cgagaaaagg tcgcttttac accagataaa ttaactcaag
   706381 cattaagtga tcttcatggt atttatggta tttatgcttg cattattctg tctacctgta
   706441 atcgtgtaga gatttatgtt aattctgata atgaaaaccc taaagaagta ttaagtaact
   706501 atcttgctaa aatacacaat atcacacgtg acagaattaa cccttattta aattattttg
   706561 aggacaatga agcgcttaca catgtttgca atgttgctac agggcttgat tcattagtat
   706621 taggagagcc tcagattcta ggccaattaa aaaatgcata ccatatggca aaagaagcca
   706681 aaaccttaaa taaattatta gaaaaactat tccaacacgc attttcaact gctaaaaaag
   706741 tacgtactga tactcaaatt ggtgtttcac ctgtttcaat tgcttattgt tcggttaaac
   706801 ttagtgaaaa gatttttgaa tgtttatctg aacaaactgt tttactcatc ggtgcaggag
   706861 aaatgattga attatgtgca caatacctaa acaaaaaaaa ggtgagtaac atgattattg
   706921 ctaatagaac cattgaaaat gcacaaaaaa ttgctaactt atatcaggca caatctattg
   706981 gcttaaaaca attttcatct gttatacaca aagcagatat tattatttct tcaacagcag
   707041 cttcagtacc cattattggc aaaggattaa ttgaaagtgc cttaaaaaaa cgcaagcata
   707101 aaccaatatt tatgcttgat attgccatac ctcgtgatat tgaacctgaa gtaggacaat
   707161 tagatgatat ttatttatat actattgatg atttagagca agtgatcaat gataacatag
   707221 gcaatagaga aaaagaaaaa aacctggcac aggaaattat aatcaaacaa aaccaagtgt
   707281 ttaatcaatg gttgaaagtt ttacctaatg aacaattagt acgatcttat cgttctaatg
   707341 ctaacttaat taaaaataaa ctattagaaa aagccatcaa acagattaaa catagtggtg
   707401 attatgagaa tattattcgt aaatttgctg accaattaac taacaaacta ttacacttac
   707461 cttctaaaaa tatcaaacaa acctccactg ataatttatc tcagtgcgaa ggttgtatac
   707521 ccaatattaa aaaataatga attcatctat cctagctaaa ttagagcaat tatcaatacg
   707581 tcttgaagag gtaagtatta tgctatccga tccagaggta gttagtaacg ttaaaaagtt
   707641 cacaaaactg tccattgaat acgctcaatt aaccccagtc aaccaacaat ttcaaaccta
   707701 tttatcacat ctaaaaaacc tagaagatgc acaattaata ctatttgaag acgacatgga
   707761 aatcaaaact atggccaaag aagaaatact taataccaaa aaaattttaa gtcagcttga
   707821 tttaaaactt aagaaatcta tcttaccaaa agaccctaac gattctcgaa atataattat
   707881 tgaaattaga gcaggtacag gcggcgatga agccagtatt ttttcaggtg atttgtttaa
   707941 aatatatagc cgatacagcg aaaagcagaa atggacaata gaaattatta gctctagtat
   708001 tggtgaacac ggtggtttta aagaaattat tgcccgcatt agtggaataa atgtttactc
   708061 aaaattaaaa tttgaatctg gtgcacatcg tgtacaacgc gtgccaacaa ctgaaagcca
   708121 aggtcgaata catacttctg cttgtaccgt tgccatcatg cctgaagttg aaaatattga
   708181 agaaatcaat attaacataa atgatgttcg tattgatact ttcagagcca gtggtgcagg
   708241 tggccagcat gttaataaaa ctgattctgc tgtacgcata acacatcttc caactggaac
   708301 tgtagttgaa tgccaagatg gtcgttcaca acataaaaat aaagcccaag caatgtcagt
   708361 gttagcatca cgtattcttg atgcacaaca acaagaacaa caagaacaac aatcatcaac
   708421 tcgtaaggag ttaataggta gtggtgatcg ctcacaacgt atccgtacct ataattaccc
   708481 gcaaggacgc attaccgacc atcgcattaa tctaacctta tacaaactaa cagaaattat
   708541 ggaaggtaac ttaagtgcaa tcattaagcc attaattatc gaacaacaaa ctaatcaact
   708601 aacggagtta aataatactt aaaaactatt atatcaatca aatataggaa aaaccatatt
   708661 tttaaaatag ctgttcctat agttatttag aggtgataaa aaccaccata tacaaataca
   708721 tctacacagg aagctaagtt aataaataat aaataataaa taataaataa taaatataat
   708781 tttacttaaa agttctttct atctagaaaa agagttaata caaacctacc attagttaaa
   708841 actatacttc ctttatctta ctagataaag aagctaaaca atatttttta ttaaaccaaa
   708901 tacaaataac tcttttagtg tttatttaaa gcaaaaaaaa ataacaatta cagtaatata
   708961 acaaaattct agatacttcc taaatttttt aaaagaaaaa agtggtcatt ttataggttt
   709021 cataaattat attaatctct ttaaattaat tttttatatg caaattgtga taataagaat
   709081 aacacaccta gagtaattac gatagctggc cctgttgcta catcataaaa cattgaagcg
   709141 ataataccaa tagtaactgc gaccatagaa acaataactg actgaaatac catgctacta
   709201 ggtgtattgg aaaatactct agcaacagct ggtgggataa tcagtaagga ggtaattaaa
   709261 agcacgccca caatttgtac tgaaacagac acagctaacg caatcattag cataaataac
   709321 aactgataaa aatctctatt aagcccttgt gcaactgcta attcttcatt tagagttagt
   709381 aataataaac gctgccaaaa aataatgagt aataatccaa gtaccgtcaa aattacatac
   709441 acccaaacaa tatcagaatt agtgatagat aaaatatcac caaataagag tgaaaaataa
   709501 tccgtattag ttccaccaat aaaacctaaa actacaatac ctaacgataa aaaaatatgt
   709561 gaaaaaatac ctaaaatagt atcattagat aaaaaatttt ttcgttgtaa gataacaata
   709621 aatattgcaa atattgtacc taccattacc aaaccaaaat gcattcctaa gccactagca
   709681 aaccctaaag atgtacccaa aagtgctgaa tgggaaatag attctgagaa ataactcata
   709741 cgtttccaaa taacaaaaca acccaatgaa cctgaaataa ttgaaatgcc aatggctgct
   709801 aaaatagctc taaaaataaa atcttccaaa tggattagtg acaaccctta caaaaaccgt
   709861 ataaatacaa gcaatgatcg gtcagttggt aaccatattt attagcaata tcatgctgat
   709921 gttgctcaat cacctcatca gaaaattcgt caattttacc acacttaatg catactagat
   709981 gatcatgatg atctacattt gatagctcaa acacactttg accgttatca aagttaagtt
   710041 tatttaccat gcctgcctct tcgaactggg taagtactct atagattgtc gctacaccca
   710101 cttctgcacc ttgtatcatc aaagtacgat aaatatcctc ggcgctcata tgatgattat
   710161 cactagtttc taaaatttcc aaaattttta accttggtag tgtaacttta agccccgcac
   710221 tttttaaatc ctgagcatcc atatctaata tccttaatgt aaaattagtt aataattttc
   710281 aactatttta aattaaaaaa ccagtaaatg aacaaattaa ctttgattgc attcttattt
   710341 ctatttctat ctgcatgttt acataagata ccaggcgtat cattaccaat attgtataaa
   710401 aatgatatac atcaaggttc aatactggaa agatttaaaa ttaatcaatt aaaattagga
   710461 atgtcaaaag ctcaagtaca aaatctaatt ggttcaccaa gtattattga tacatttcat
   710521 aataaccagt gggattatat taatcactct actttatata aaaaagacga tattcactat
   710581 cgcctgatat taaagtttaa taataacaat ttgatacata tcaataccag tggtattaac
   710641 tcattatcac agttaactga taaagaaaga aaaatagaaa acaaacgtat tagagataaa
   710701 caagcatcag aaaaagctaa agtagtagta aagattactg aagaaaaaga tttgtctaaa
   710761 gctaaaatat taaagagtga tccaagcaca ctattcgtaa attaaccaat taaataaaaa
   710821 ataatatcaa tgataaataa gttgttaata caaaaatatc ttggtatgga ttctaataat
   710881 tatctacctg taaaaagcca attaaatttt tagatattaa cttatcacta atagccaatg
   710941 caataccatt aatacttgct tcagttaatt gttctaatag agtcttttct ttttcaaata
   711001 agactcttga atcaatacca ataatatgct tagcaacata attcgtatct gcaataccat
   711061 ctattaaccc taatttatta gcatcttgcc ctagccaaat caaacctgta aataaatctt
   711121 tatgttttga taacctgtta cctctacctg ctttaacagc attaataaaa ttttgatgca
   711181 atttatctaa tacatgaatt tgaatgtgcg ctaatatttt ttcattttct ggagaaaaag
   711241 agtctaacaa tcccttatat tttcctgcgg tatagagccg tcttttaata cctaattttt
   711301 taatagcatc aactgcacca aaactagaca taataacacc aatactacca ataattgaag
   711361 attcatctgc atatatttca tcagcagctg aagcgatata ataacaacct gaagcgcaaa
   711421 catcttcaac caccacgtaa aattttttat caaattgttt ttttaaacgg ataatagcct
   711481 tataaatcct actagattgt acaggtgaac cacctggtga attgattctt aaaataatag
   711541 cttttgcatt ttctaactta aatgcactat ataataactc aatagtctca tcagcatcaa
   711601 ttgaacctga actttgaata gtaccactta gcactacttc agcaacaaaa ggagattctt
   711661 ttttaagtgc tgtatttaat acgccatttt cgctaatacc tatataatat ataaaaataa
   711721 aataaccaac aaataatatg ctaaatataa tacgccaacg atatttggat ttattttgac
   711781 gtacaaattc ttgtgcaata tcggctagtt gttcatcagc agtacgtttc atatataatc
   711841 ttcatttatg ttaaaagtag ataatcttag ttgccaaaaa ggctacaacc ttttattcag
   711901 caatctttct tttaaagtta actcaggtga tattttacgc attactggca ctaatggtag
   711961 tggtaaaact tcacttctta agattctagc cgggcttgat attcaagaac aaggtaatgt
   712021 ttttttagac aatcatgcac tcaagtcaga agcctaccaa caagaaattt tttatttagg
   712081 tcacttgtca acacttagtg aagaattaag cactcttgag aatcttgaat ttttaacaaa
   712141 acttaataaa tctaccaaac aaatacaatt aactaaagca ttaagcagta tcggtttaaa
   712201 aggttatgaa aatgaatact gcgacaagct ttcagcagga cagaaacgac gcgttatcct
   712261 agcaggatta ttcatttcta atgcaaaaat ttggctatta gatgagcctt ttactgcact
   712321 tgatactgat ggtgtaacaa tcattgagag tagaattaca aaacactgta aacaaggtgg
   712381 attatgcttg tttactacac atcaaaattc agacctcctt aatcaaaagg tgttagcact
   712441 atgaatattt acctacaagc tttaaaacgt gacttgcgta ttgctattcg caatccttct
   712501 agtatactaa accctctgtt attttttata atatcggtat cattatttcc cttagctatt
   712561 agctctgaag ctaccatact ctccccaatt gggtcaggca ttatctgggt tacttcaatg
   712621 ctctcaatgc tactttcgct taatgcttta tttcatcatg attttgaaaa tggtgtttta
   712681 gaacaaatgg tgatttctca ccattcacta cctttactta ttctatcaaa aattaccgct
   712741 cattggattt tgactggtat tcctattatt ctactatctc ctttatttgg attattttta
   712801 tttcttgata ataatggtct ttatgtatta atgataacac tattattagc cacgccaagt
   712861 ttaagtctta ttggagctat tggggcttca cttattgttg gtataaaaaa ttctggcatg
   712921 ttattatctt tgctgatact gcctctgtat attcctattc ttatttttgc ttcaagtgct
   712981 gtctctcaag cacaatttgg tttaggaatt acaggtcaat tgtatttttt agctactgtt
   713041 ctcatagtga gtttaatgag tgcgccattt attagtggta ttgctttaaa gataagccta
   713101 gaataatcaa ttaattgtgc tataatttta actatacgct gatttgtccc gattgctagc
   713161 gttgctacca aaataggaag ctaaaacaag ctaaagtagg tgttcttctt tattagaaac
   713221 ccgctttaag ggtttttatg ttttatatag gagaaaaaaa tgatattcac ttctgaatct
   713281 gtatccgctg gtcaccctga taagatttgt gatcaaattt ctgatgctat cttagatgca
   713341 gcattaacac aagataaaaa ctcacgtgtt gctgttgaaa cattagttaa aggtaatcat
   713401 gtcgtactag ctggagaaat taccacaggt gccaatattg attatgaaaa aattgtgcgc
   713461 aatactatta ttgatattgg ttatgataaa caagaatacg gttttaacgg taacacttgc
   713521 aacattacca atttactcgg cgaacaatct caagacattg ctataggtgt taatgaatca
   713581 tctaatcacg aacaaggagc aggcgaccaa ggtttaatgt ttggttatgc ttgtaatgca
   713641 actgatacat taatgccagc ccctatttta tacgcacacc ttttggttgc gcgtcaagca
   713701 aaactaatga aagatggtgt attaccttgg ttacgaccag atgcaaaatc tcaagtatcc
   713761 atgatttata acggtcataa aatcgtgggt attgatgccg ttgttttatc aacccaacat
   713821 gataatgata tttcacttac agatttacga aaagttatct tagaaaaaat aataaagcct
   713881 gtactaccta gtaaatggct aagtaataaa actcagtatc acatcaactc aacaggtcat
   713941 tttgtcattg gtggtccggt aggtgatgca ggcctaacag gccgtaaaat tattgtcgat
   714001 acttatgggg gcatggccag acatggtggc ggtgcatttt ctggtaaaga cccatcaaaa
   714061 gttgaccgtt ctacagcata tgcaacacgt tatatagcta aaaatattgt tgctgctggt
   714121 ttagctgata gatgtgagat tcaagtctct tatgctattg gtgtagcaga acctatatca
   714181 attaatgtag aaacctttgg tacaggaaaa atcaataatc aagcaattga acatttaata
   714241 cataaacact ttgatttacg tcctaaaggc ttaattgaaa tgcttgatct taaacgccct
   714301 atctatcaac aaactgctag ttatggccac tttggacgta cagaaaatga cattagttgg
   714361 gaaaaaactg atcgcgctca cttactaaga taaatcatta ttggtataat aatcaaagtg
   714421 aataacccaa ccttaaacaa taaagattat aaagtcgctg acatgaaact ggccgattat
   714481 ggtcgtaaag aaatagagct tgcagaagcg gaaatgccga cacttatggc acttcgagaa
   714541 aaatataaaa gcaaacaacc tttaaaaaat gccaaaattc ttggctgtat ccacatgact
   714601 attcaaaccg ctgttttaat tgaaacactg atcgatttag gttcacaagt acgttggtca
   714661 agttgcaaca ttttctctac tcaagaccac gctgctagtg ctatggtagc agctaacatc
   714721 ccaatctttg cctggaaagg tgaaactgaa gaggaatttt tatggtgtat tgaacaaact
   714781 attttaaaaa atggtaaacc ttgggcagct aatatggtac ttgatgatgg tggtgatcta
   714841 acccaaatat tacacgagaa atatccagag atgttagcta acattcacgg tatttctgag
   714901 gaaaccacaa caggtgtcca tcgcttatta gaaatgatga aagaaggttc acttaaagtc
   714961 cctgctatta atgtaaacga ctcagtgact aaatcaaaaa atgacaataa atatggttgt
   715021 cgccactctc taaatgatgc tattaagcgt agtactgata tgctcatgtc aggcaaaaaa
   715081 gtactagtaa ttggatatgg cgatgttggt aagggctctg cacaaagcct acgtcaagaa
   715141 aacatgattg ttaaaatcag tgaaattgac ccaatttgtg caatgcaagc ttgtatggat
   715201 ggttttgaaa ttatttctcc ttatatcaac ggcatcaata caggtctaat tgataacatt
   715261 aataaagatc tgctaaatac aactgattta atcgtcactg ctacaggtaa tattaatgtt
   715321 tgtgacaata ctatgctaca aactcttaaa ccaggggcag tggtttgcaa tattggacat
   715381 tttgataatg aaattgacac tcaatatatg cgtgataatt ggcgttggga tgagatcaaa
   715441 cctcaagttc atcgtatttt tagaacagac aataaaaatg actatttaat tttattgtct
   715501 gaaggacgtt tagtaaattt aggcaatgca acaggccatc caagccgcat catggatggc
   715561 tcctttgcca atcaagtctt ggcacaaatt cacttgttta atgcaaaatt tgccgataat
   715621 gggggtaata tttatgttaa agttcttcct aaaaaactag atgaagaggt agctgcaggt
   715681 atggtgtatg gttttaatgg cgtacttact atactgacaa ctaatcaagc taattacatc
   715741 aatgtcccaa aaaatggccc attcaagcct gagaattata agtattaagg ccatataaag
   715801 tgttttaaaa aaatactctg gtacaagatt tttataataa ttttacggta aaattttttg
   715861 ttatttttac tgaattaata tgttaatttc aaatttagat acttgtgttt cattccagaa
   715921 tttaatctta aaactacaaa ctttttggag ctcaaaagga tgtgttctat tgcaaccttt
   715981 tgatatggaa atgggtgctg gaacctttca ccctgctaca tttctaagag ctattggtcc
   716041 tgaaccttgg aaagcagctt atgtacaacc ctcccgtcgc cctaccgatg gtcgctatgg
   716101 aaaaaatcca aatcgattac aacattatta tcaatttcaa gtattactca aaccatcacc
   716161 aataaatatt caagatttat atttagaatc tttagctaga attaatattg atttaactaa
   716221 gcatgatata cgttttatag aagacaactg ggaatcacca actttaggag cttggggttt
   716281 gggctgggaa gtttggttaa acggcatgga aatttctcaa tttacctact tccaacaagt
   716341 tggcggctta acttgtaaac ctgtatcagg agaacttact tacggattag aacgtttatc
   716401 tatgtaccta caaggtgttg atagtgtatt tgatttgatt tgggttgagg ggattagtta
   716461 ctctgatgtg tttcatcaaa atgaaattga acaatcacaa tataactttg agattgctaa
   716521 taccgaagta ttatttaggc aattcgacga agcagaaact atgcataaaa aactaattga
   716581 gagattattg ccctatcctg ctcatgagca agttattaag gcttcacatt tatttaattt
   716641 acttgatgca cgtcatgcta ttagcgtaac agatcgcgca cggtttattc gtaaagtacg
   716701 tgctatgagt caaaaagtag cacaaactta ttacgactca cgcaaagctt tagactttcc
   716761 aatgcttaaa caacccacaa aagtcaagcc aagtaagaaa taacatgaat atattttcca
   716821 aaatttattt aaggattctt aactgggttg aaagcaaata taccatttat tacttatcag
   716881 tagttagttt tttagagtct agtattttac cttacccgcc acctgatata atactagtac
   716941 ccatgacact caaacaccct gaaaaagcgt actattttgc ttttatttgt actatttttt
   717001 cagtattcgg cggcttaacc ggatactttc taggtgaagt attattacaa tttttgctga
   717061 attttgaact tatcaaacca gaatcagtca catatataaa aacatctttt aatacttatg
   717121 gtatttgggt agttggtatt gtagcattta gccccattcc ttataaatta gctaccatta
   717181 ctgctggaac tatgtccata gcattattac catttattat tatttcactc attgcacgtg
   717241 caactagata ttatctagtt gtttcactaa tcaaagctta tggtcaacaa tatgatcagt
   717301 ggctaaaaaa atatatcaat catttaggct atattataat tatagttatt gcactaggtg
   717361 cttggtatgc cagttaaatt tttagctctt ggactaggct tactattaat aacaagttgt
   717421 ttttattctc aacaagaagt tattattatt gaaaagtcta ccaatctaca aaacattaaa
   717481 aagataagca aaaaaatcaa caaatggtct atgccagttg aaggcaatat aagaaaaacc
   717541 ttctcaataa aaaataaaca tttaggatta acttttgata ccaacactgg aaaaaatgta
   717601 cgcactattc gtaatggtga ggtagtctat gctggtaata aaataaaaaa tcacggaaaa
   717661 atgattatta ttcgtcaccc atttgggttt tacagctcat atacacaaaa caagacctta
   717721 atggtgaaga atggggattt tgttaacaaa ggacaaataa tcgccattac cagtaaagtt
   717781 ccattttact ttgaaatgaa aaagtttcaa caaccaatta acccactaaa gtatctaaaa
   717841 taataaacta aaattcaatg aatgattttt taaaaaacat aatatcttat caaaatatta
   717901 ctgaaattat tcaaaataca atactgaaat ttattatcca atacaaacac tacaacttct
   717961 cactaaagga tgcatatcta aaatgcaaaa taacaattga taaataaatt atacattcgt
   718021 acttttgggt gtcaaatgaa cgaatatgat tctaataaaa tggttgatat acttaaacat
   718081 tcccatgacc taacactaac tgatgatgca actagtgctg acgtattatt acttaacact
   718141 tgttcaattc gtgaaaaagc ccaagataaa ttattccatc agctcggtcg ttggagtaaa
   718201 ttaaaaaaca aaaatcctaa tttaattatt ggggtaggcg gttgcgtcgc ttcacaagaa
   718261 ggtgaattaa tccttaagcg tacaccttat gtggatatta tttttggtcc acaaacctta
   718321 catagattgc caaatatgct caatgatgca ctcaataata agaaaactag tattgacatt
   718381 tcatttccag aaattgaaaa gtttgaccat ctaccaaagc caagaaccaa ttctgttacc
   718441 gcttttgttt caattatgga aggttgtagt aaatattgta cattttgtat tgtaccttat
   718501 acacgcggtg aagaaatatc acgtccattt aatgatgtca taaatgaagt taaaatctta
   718561 gccagccaag gtgttagaga gattaactta cttggacaaa atgtcaatgc atatcaaggt
   718621 tctatgaatg atggagaagt ttctgatctg gcactgttaa ttaatattgt agcaaaaatt
   718681 agtggcatta aacgtattcg atataccact tcacacccaa atcaatttag cgatagttta
   718741 atagaagctt acgccgaagt accagaattg gtttcacatt tacacttacc tgttcaaagt
   718801 ggatctgata aaattcttag attaatgaaa cgtggatata tgtctattga atacaaatca
   718861 aaaattagaa aattacgtaa aattcgtcca gatatctcta tatcaagtga ttttattatc
   718921 ggttttccag gtgaaaatga gaaagatttt cttgatacta tgatactaat tgatgaaatt
   718981 ggctttgata aatcatttag ctttatctat tccgttcgac ctggcacacc agctgcaagt
   719041 tatcctgatg atatcgatat acaggttaaa aaacagcgtc tagcactgat acaaaaaaca
   719101 ataaacaaca acactgaaca catttctcaa ttaatgattg gtagtataca aaaagtattg
   719161 gtggaaaata taactaaaaa aggaaatgaa ttatttggac gtacagaaaa tatgcgtaac
   719221 acgcatttta aaggtgataa atctctaatt ggtcaaattg tcaatgtaaa aatcaccaaa
   719281 ggtcgtggta attctttaat gggtgattta ctaactcaaa tttagatcgg tttcaaaaaa
   719341 aataagactt tccaaatctt ttccctgtaa tcatgattat gttggcaact taatatattt
   719401 tactaagtaa gtataaggca aaaaataatt ttttccttga gaattatttt tatcttgctt
   719461 ttgtaaatta agatgacaaa ttatggttaa tttaccaata aacctcatat ctctctatta
   719521 taaagaatca ataataaacg gctttgtctc taaaatgcat cataacaata ttttatgtac
   719581 taatatttat ctttcagtaa ttattgctcg acataatgac tttgtcattt aacaatactt
   719641 aactttaact atacaatcaa tagagtttta cacaaaccat taataagaat aattaataat
   719701 aaactaatgc tgagggcttt attttttaaa aatttttaat gataaattca atatcatctg
   719761 caattttaat cgggtcatgc ggagtaggaa agcccgcaaa tatttgtcca tctggattga
   719821 gtagataaat ccaagcagta tgattaatta agtagccaga ttctagaata ccttttgaca
   719881 atggttcatc atttttgagt actagtaact taccattttt ttcataaact acccgttcat
   719941 aatatacacc aaagggctta ataagctgat taatttgtac ttgatcacca gacacaccta
   720001 aaaagtcttt atcaaaatga gtcacataag tttttaacac actaggtgta tctctagctg
   720061 gatcaaaggt aatagcaaca aggtttggta taatatttaa acctctttta atcaaagtgg
   720121 atttgagtat tgacatatct attaatacgg taggacatac atctggacag tgtgtataaa
   720181 taaaggatag tagcgtccat tttcctttaa gattattatt atcaaattta ttattgttat
   720241 ggccaactag cgaaaaagaa ggcaattttt tatcaggatt atgaaggata taagagactt
   720301 taagttgttt ttctaaatct tgataacttt tactaggact tataaaatag aatatcgaaa
   720361 taaccgacac aactactaca ataccactaa ataatttatt attcataaga ctaatacata
   720421 atgattactc attatatttc cttaattatg taagattttt actttattgg cagaactaca
   720481 aagaaaggat tttaactttc aactatagga ttaaataata gctttgaaat aagttctaga
   720541 cttcctattt tcacactatt aataaaatta gcatattcaa atataactat ttttgaatat
   720601 gctacaacta taccattatt tttgataaaa ctcttaagta aatcttaaac agatttactc
   720661 ctaaaaagaa ataaattatc ttttagagac tttttcatga gtaggcgata atagtgtagt
   720721 tattacttta ataaaaaaag ttaaaacttt tagtggtata cctctgtact atgatgatta
   720781 tctatcgttt tctttcctat tctaacttca gcatgtacga tttttgtcaa accattgtca
   720841 aagatcaact caaacatcac tatatcacct ttatgtaaca ctaacttagg actaatcaac
   720901 ataatgtgcc aactacccgg ttttaaatgt agcttacctt tagctgggat tatcataaat
   720961 tcctgtttaa ccattttcat tatatcatct tgcgccacag ttctgtgcaa ttcaatacgt
   721021 ttatagtcac cagcatttac agaaagtaat ttaatatcat gattggtatt attattaatt
   721081 tgcataaaaa gacccaatac tgatgcatta gttggtgcta aacgtaccca tggatcattt
   721141 atcataattt cagatgtaat atggttcatt tgataatgtt ccattgcaat ggatacatac
   721201 aagattatta aaataataaa tgctaatata agtttcttta ctttattaaa cataattttt
   721261 acctttctta agaattaaag ttgttactgt tattctgttc tcaaattaga aacagaataa
   721321 aaaatatctt tgcacttatg cctattaaaa acttaaaaaa gtagctttat caaatctaac
   721381 tacttctagt atatcatata ccataaacta tactattatt cttaataaag gaaatacaaa
   721441 ggttttatta tgatgtcaac aaaatagacg agacacgaat agccaaaaac tatcacagca
   721501 ttcttaactg aatattattc agaatgactg tagaaaaact acatatatgt ttatctataa
   721561 aatcaaaata atattttgcg ttagaaacta caatatcaaa taccttggta tttaataaat
   721621 attaacgaca gcctaattca acataatttt gattgtgcta tttattatcc aaataatatt
   721681 atttaaatga taaaatataa taaatgttaa tttcatcttt aaaattaaca ataaaagaca
   721741 attagtcaaa tatttttgag tcattttaac tagaacttaa accacattac aaatatttta
   721801 ggtatttatt tgtttatatt gccaataata gggattttaa tattatagaa aataaacagc
   721861 acatgaggta gaaatagcca ttaacactca cacaaaataa taacttaaca gaatgaggtt
   721921 attcatatta aaccaagcgt aaattgattc atatgcgtaa ttaaaatcag caatactatg
   721981 taaataatac taaaaactaa gggtattgta agacttattt ttcagtaaca cgtgccatta
   722041 aaagaatata tgacaactga ttctagcatg ttctgtagtt taagcataaa ttagattttt
   722101 acctgacaat ataaataaaa agattgactc ttatttgtga cttaattatg atgaagtgta
   722161 tgaaataata aacttaaatt cctggataaa atataattga gatcatacca ctgatattta
   722221 tactaggtaa aattttaaat gagataaaaa acaccaccat agaataaatt aatacagtac
   722281 atcattttaa tgtatgaaaa atttaaataa aaatactaaa attatagttg gtttatcagg
   722341 cggagttgat tcttcagtaa ctgcactatt attacttaaa caaggctacc aagtagaagc
   722401 attgtttatg aaaaattggg aagaagatga taaaggcaga tattgtagcg ctaaacaaga
   722461 cttatctgat gcacaaaata ttaccaataa acttagtata aaattacata ctattaactt
   722521 ttcagtagat tattggaacg atgtatttac tcattttcta aaagaataca aaaaaggtcg
   722581 aacacctaat cctgatattt tatgcaatca aaagattaaa tttggagcat ttttaaaaca
   722641 tgctatatcg ctaggtgcag ataaaattgc tacaggacat tatgctcgta ttgctaaaaa
   722701 aaatggaact tatcaactca aaacaggttt ggacaacaac aaagaccaaa gttatttttt
   722761 acatctttta agtcaatatc aactctcaaa aagtctattt ccattgggtg agaccaataa
   722821 aattgatgta cgtaatattg ccacagaaaa tggctttgtc actgctaaaa agaaagattc
   722881 aacgggcatt tgttttattg gtgaacgtaa attttctgag ttcttagcaa cctatctacc
   722941 aaaacaacaa ggcaatattg taggcgaaca aggacaattt attaaacacc atcaaggttt
   723001 ggctttttat acaataggtc agcgcaaagg cttagagatt ggtggaggtt ttggtaaatc
   723061 aggtaaacca tggtttgtag cagataagtg tattgaacgt aatgaactag tagttgtaca
   723121 aggtgatcat acactgttat attatcaaac cttaaatact tctaaacctt attggattaa
   723181 cacaccacca acactaccca tgacatgcaa cgccaaaata cgttatcgtc agcaatcaca
   723241 atcttgtatg attagccagg ataataataa gcaattaaaa attattttta agcaacctca
   723301 acgtgcaatt actccaggac aatctattgt tttttatgat aatgaaactt gtcttggcgg
   723361 ggcaattatt gagtacagat aataatgaat aaattacgcg aacaaactct ggcactagct
   723421 agtatattac aaactacaac actaattgac caacttgctt caactggcac ctgtgatgca
   723481 aatagcaatc aagccagctt aaaaagtatc attaccagta gtaccaaact tgaagaggtt
   723541 tttaatcaaa aacaagattt attagttggt attgatgcgt taaaagttgt attaagtaat
   723601 aaaactaaat gtatacaaca tataatattt tacgcattag ccttgattaa ccttgaaaag
   723661 aaattgatga aaaatcaaac actactcaat caaatcactt tagaaattga cttaattaga
   723721 aatcaagatt tttttgagat ttctcatata aactcaatag cacgtttagc tcaactttat
   723781 aaatcaaccc taggtggttt aaatcctaaa attatgatca acggccaaca aatttaccta
   723841 tctaataaac atacttcaaa tcacattaga gcgttattat tagcaggtat tcgggcagta
   723901 tctttatgga aatctcaagg cggtaaaact tggcatttat tactaaataa gaaaaagata
   723961 cttaatttaa ttaatacgtt agaaggatta aattaataat gccgataccc tatagacttt
   724021 tatcgttgaa gagtctataa tcacattcat attcaatata ttttattact ttatttaaca
   724081 ataatggcta attcagcaag ttctagaaaa cgcgcaagac aggcagttaa acgcaataaa
   724141 cacaattcac aaattcgcgc taaggttcgc acttttatta aaaaagttac ttacgcttta
   724201 gaagcaggta ataaggaaca agcacaaaat tgttttacaa taatgcaaaa gatgcttgac
   724261 caagcagtta ataaaggatt aatacacaaa aaccaagcgg ctagaaaaaa atcacgccta
   724321 aattcacaaa tcaaagcatt ataaaattaa cactaaattt tttgaaaaac cataccttgt
   724381 aaggagtttt tggtattccc gtctttacaa tagtataaac cattttttta aaaggtatgg
   724441 tttttcaaaa aatttagtta tactaatacc tcatcataat caattctcat agaaagtatc
   724501 atgataagca agtcagacaa aatattattt agaagtacca ttgaaaacag cattcctatt
   724561 aataaagaca aaattgtact tcaaaactta actaataaaa aagcctttaa agcctataac
   724621 tatattactc acggcagttt agctggttca gatataatta gctatgccaa aaatagcgtt
   724681 tcaccaaaaa taatcaaaag aatgaaacaa ggtaatatta gtcacgcgcc aatattagat
   724741 ttacacggcc aaactaccat tgaagcctgt caatcattat ctgaatttat tcactaccat
   724801 caacaccaga aattcatcca tattattcat ggaaaaggtt ataattctgg ccaagataat
   724861 ggtattttaa aaagccaagt agttagtttt ttacgtcaac atcctgaggt attagctttt
   724921 aactcttgcc cacccaaaga tggtggcaca ggtgcagtat ttaccctttt aaaacaaaac
   724981 taagtttatg tttaatattg atgaggttta cacaatctct agttttctat ctgtctgcaa
   725041 taaaaccatt gaaaataata ttcctacttg ctggctacaa ggagaaatat ctaatttaac
   725101 acgaccagca tcaggtcatt ggtatttttc tctcaaggat aatacagttc aggtgcgttg
   725161 cgctttattt cggttcaatc aacgttatat taagtttagc cctaaaaatg gaatagaagt
   725221 tttagttcgt gttgtaccta ctttatacga agctcgaggt aattttcaac tcgtcatcca
   725281 acaaattgaa caaataggta ttggcaattt aaatcttgca tttaaacaat taaaaaaaga
   725341 ccttgataat gaaggtttgt ttgataatat ccataaaaaa ccattaccta atactattaa
   725401 caccattggt gttatttctt catccacagg tgcggttatt caagacatta ttaaagtatt
   725461 gaataaccgc tatccatttg ttaaaatttt gttatttgac tcaatagttc aaggtcaaga
   725521 ttcaataaaa aaacttacaa acgccttgaa tatagctgac caatctggca aatgtgacgt
   725581 tattattatt gccagaggtg ggggttcatt agaagacttg tgggcattta atgaagagat
   725641 attagcaaga gcaatcttta acgcaaaaac cccaattatc agtgcaattg gtcatgaaac
   725701 tgacactaca attgctgatc ttgtttctga tattcgtgca cctacaccaa gttttgctgc
   725761 catgttagtt acgtctaacc gattagaatt gctctccaat accaataagt tatacacgca
   725821 actacatcaa tcttatcgac aaaccttaca ttattaccaa tctcgtctta atcaacttaa
   725881 attaaaaata tcaaacccaa ataaacaaat tgattattta aatcaaaaac ttgattattt
   725941 aagtattaat cttactactc gtaaagaatc tatattcact ctaaataatg ctaaacttaa
   726001 ttcgcttttc accaccttaa agcaacactc tcctattaaa actattaaac acgctaaatc
   726061 tttgaatcaa atgtctttga atcaacttaa ataccaaatt aagcaaataa ttaacaccaa
   726121 taataatatg ctatatttag caactgaaag gcttcaaaag ataattatgg ctctaactaa
   726181 taaacataaa gcaagattat ctattcaagc caactcactt cattacttgt caccacttaa
   726241 tatacttgca cgagggttta gtattactag tgatactaaa aatcaagtat tatcatcagt
   726301 aactaatatt aaaatcaatc aaactattat aactcaatta gataatggag cactatactc
   726361 taacattgaa aaaattgaaa agaattaatt agcacatcaa tactttcaaa aacaagaaag
   726421 aaatataatt ttactactaa aaaaattact tttacaatac aactatccca ctagtaaaaa
   726481 gaaaaaatat ttcaatttaa ccttaaacca tatcaatcaa attaaatacg aatgccttat
   726541 tttgtcaaaa actaaaaagc tattttctta aaaatcctta tgtaatggtt aatttatcaa
   726601 aatttattaa agacgtcgtt actactaact cctctagact taagtatttt tacaatagac
   726661 aaccacatca gccaaatctt ctaaataata taagtacatc aatacaagcc cggcagaaaa
   726721 taataagtaa tattcataaa gctattgacg ataacactat atttattaac tacaaataaa
   726781 ttgatcaatg tttatattca cacgcataaa cacctaataa aataaagtta attaattagc
   726841 actattggac aaactaggtg catcatagtc catcacttac attgaggtat ttatcttagt
   726901 caagacacag tgaattcaaa attgttacta aacatatgac taactctatt aaaaaaataa
   726961 acgctatatc gtatgatatt accttagcat ttgctttgtc aaaagcacta aataacaatt
   727021 ctttgtttta tgtagtaact catataaata acttaaccct attatgaatt gacaaaggca
   727081 ggaaaacact aggcataaag tcttaaaagt taaaaattaa aaaaacgata acaatattgc
   727141 tctcaaataa gtgttcactt aattaatatt attctaattt tttggtttag gttttttata
   727201 tcaattatct aacaaaagaa atagagcatt gcactacaaa atttctaata tcattttatc
   727261 aaaaattgat ttgtattaac attaccgaca aaaaacctat gctataatgt tatataatat
   727321 gagatattgg ggatgaaaaa tgagttcaac agttgataat agtaacataa gaggtaatat
   727381 tcttatgtta agcacattaa ttataacttt tatattacca ctaatattaa ttatcttatc
   727441 ttatatcggt attatatctg gtacgtctga atatatctat gcatttgcag ttataacatc
   727501 tatgatttat attgttggag gtactatttg gatgtttacc caagatttaa aagatagtaa
   727561 acaactcttt gacggctaat actatcacct attcagttga atatcaaaac atttatacag
   727621 tttatccaag ggtagaaaaa accaaataat ctatttagat tttttataat tatcagacag
   727681 attataatta ttatcttagt gtcattaatt acagtcattc gttaaatatt agttggataa
   727741 caatttttgt tttgtgatat atgataaaaa attattaatc aaaaaaattt aaactaatca
   727801 aacacttgat aaagaaaata aacaactatc aattaatctt aaaactaaat cagaagcaaa
   727861 ttttggaata tattgatata tataaactta aactacttaa aaaagatgag aaatattatc
   727921 caatgagcca atcaagataa gatttaattg aaaaatgtct aacgattatt atttaattat
   727981 tcctgctggt ggcataggta cacgtatgca ctctgaaaag gacaatatta acaggaaaat
   728041 taaaattgct aaacaatatc taaaattaga taatggacta actatactcg accaaacatt
   728101 aaaaatatta cttaatattg atcaaataaa aggctgtatt attgcacttg caaataaaga
   728161 ttatttattc actaaatcaa aatttaacaa ccactcaaag ttaataacaa cagttattgg
   728221 tggaaaaaag agaatgaact ctgtttttaa tggacttaaa gcactcacaa accttgctaa
   728281 agatgatgat tggatattag ttcacgacag tgttcgtcca tgtgttaaag catcagaaat
   728341 aatcaactta atgaaccaac taaaacacca tgaaacaggt ggattacttg caactaaagt
   728401 tgtagatacc attaaacaag ctagcaataa tattgtcaat actactattg acaggtcaaa
   728461 tctttggcaa gctcaaacac cacaaatgta tcgttttggc gtattattaa aagccttaaa
   728521 tactgttatt aatgatggta tgaatattac tgacgaagcc agtgccattg aatatttaag
   728581 actgaagtcg gttttggtta aatctagcaa aagcaatatt aaaattacta actcagaaga
   728641 tttagaacta gcaaattttt acttaactca atataaagaa tgaaaataaa aactggacta
   728701 ggacaagatt cccacgcatt ttgcgataca aataaattgc ttattttagc aggtgttgta
   728761 tttgactatc caaaaagtct taatgctaat agtgatggtg acgtggtttt tcattcaatc
   728821 acaaatgcta tttcttctat tactggtatt aacatattag gcgctaaagc agatacttta
   728881 tgtaaacaag gcgtgactga tagtgttgaa tatttaaaat tagcgtttaa tgatttaaac
   728941 aaatggaaaa ttcaacatat tgctatttcc attgaatgtt tacatcctaa aattttacca
   729001 atgattgaaa aaatgaaact tagtatttct aaattactaa acattgcact ccaagatgta
   729061 ggcattacca ccactactgg agaggggcta actgaatttg gaaaaggtaa tggcattcaa
   729121 gttttgagta ttgttacggt gataaaataa tgaaagattt acgcatggtg tttaaatcta
   729181 gaataactaa tattcatttt gttggtattg ctggctctgg tatgagtggt attgctgagg
   729241 tgttacataa ccttggttat ggtgtatctg gttcggatat tagccaaaat aaaattactg
   729301 acaggttgaa agaaatgggt tgtcaaattt attataaaca ccatcaggat aatataaaaa
   729361 atgcacaagc ggttgttatt tctagtgcaa ttaaagataa caacccagaa gtaataaaag
   729421 cacatcaact caatatccca attgtgcctc gcgcagaaat gttagcagaa ttaatgcgtt
   729481 ttagatttgg tatcgcaatt gcaggcactc acggaaaaac cactactacc agtattatta
   729541 cccatattct caatatggct gaacttgacc caacttatat tattggggga atattaaatt
   729601 caagtggaat taatgctaaa ttaggtgaaa gtgactattt aattgctgaa gcagatgaat
   729661 ctgatgcttc atttttacac ttacaatcca tgttaagtgt aattaccaat attgaccatg
   729721 aacacatggc aacttataac aatgactatc aaaaattaaa agatgccttt gttagtttta
   729781 gtgctaattt accgttttat ggtacatgta ttatatgcat agacgataaa ggtgtgaatg
   729841 aaatattaag cgacattcat agaccaatca tcacttatgg ttttaataat ggtgctgata
   729901 ttcaagctat taatatcaag caagttgata tgcaaatgca ttttgatatt atttatgata
   729961 aatatacaaa accattccct attaagctaa atttaattgg taaacataat attcttaaca
   730021 cattagcagc cattggtatt tgctgtgaac ttaatattaa ggttaacatt atccaaaagg
   730081 cattggctaa cttttctggc gttgctagac gacttgatta ccatggaaaa ttaaatatta
   730141 ataatctcca aatatctttg tttgatgatt atggtcatca tccaaaggaa ataagcgctg
   730201 tatttgaatc acttaaagat acttatcaaa ataaacgttt agttgttatt ttccagccac
   730261 atcgctattc tagaacacat gatttatttg ataattttac ccgtatactc agcactgctg
   730321 atgcactcat attactagat atatatccag cccaagaaaa accaattgct catattaatt
   730381 cttctacctt agctgatgca attagaaaat attctagctt aaatccagtg gtaataaaaa
   730441 accaaaaaaa gatcttagat atattaccta acattgtaca caataacgac gtgctattaa
   730501 ctttgggtgc aggcgatatt catacattac ctgaattgct aaaattcaac tatacctaag
   730561 aataactgat ttgatattac gtaatgaatc catgaattca cattgttcat ttagaacagg
   730621 tggattagcg caatattttt ttatcccaaa cgatttaaaa gatttatcta attttcttaa
   730681 aataaatacc aaaccactgt tatttttagg attagggagt aacttactta tacgtgacca
   730741 aggttttaaa ggtgtagtaa ttaagttgag caacttaaaa caaacaaaaa ttgaaaaaaa
   730801 tactatatgg gttgaagcag gtgtaacatt agcaaaacta tctagattat gctatgcaaa
   730861 ctgtctatac ggtggtgagt tcttatctgc cattccaggt actgttggtg gagcactgat
   730921 gatgaatgca ggtgcatttg gttttgaatt ttggcaacat gttgttagtg taactactat
   730981 taatcaatta ggcattgtat ttaaacgaac gaaagataat tttaatattg gatatcggca
   731041 tgttcacgct caacactcta acgaatattt tattaatgca acattaacat ttaatcaaac
   731101 aaaaccacaa aaagatatca aacaattact agataaacgt aatcaatatc agcctactgg
   731161 taaggcaagt tgtggcagtg tatttaaaaa tccaaaaaat tattttgcag caaagttaat
   731221 tgaagagagc caattgaaag gcgtttgtat aggtggtgct tgcatatcaa acaaacatac
   731281 taattttatc atcaaccaaa acaaagccag tagttctgat attataaatt taattacaca
   731341 cattcaacaa accgtaaaat cgaactttga tattgactta gagttagaag tgataattaa
   731401 atgattgcaa tactaatggg gggaaattca gcagaaagag caatttctct taaaagtggc
   731461 gaagctattt atcagacact caacaatcaa aatattgatt gttttacatt tgactggtat
   731521 ggggataact tatcagaatt ttggcaacaa gaatttgacc aagtatttat tatattacat
   731581 gggcgtggtg gtgaagacgg atatattcaa aaacaactag aaaaccgagg tatttgttat
   731641 acaggctctg attcgaatgc tagtcataat agtatggaca aagcacgcac caaaataatc
   731701 tgggaacagc acagtcttac acttgcacct tctattattg caaatattga tcaacctatt
   731761 aatcctatta actttccatt accttgggcg gttaaaccaa ccttagaagg ttccagtatt
   731821 ggcattagta aagttgacaa tcagatgcaa ttaaatgatg cattaatgct tgcctggcaa
   731881 tacgccccat atgctttaat tgagcaatgg attaaaggtg atgaatatac agtagcaatt
   731941 ttaggtgata aagccttgcc agttgtgagg attataactg atcagaattt ttatgattat
   732001 gagtcaaaat atcactcgaa taagactcaa tatttatgcc cttgtaatct aagtctaact
   732061 caggaaaaag cattacaagc cattgcactt aaagcatttt ttgctattaa tgccaaagga
   732121 tgggggcgag tagatttcat tattaaccaa cataataaac cttatctatt agaaataaat
   732181 accgttcctg gtatgacttc acattcatta gttcccatgg cggcgaaagc aataggcata
   732241 agctttaata aattggtaac gtcaattatt aatgaaatat aaacgtataa ataggttaaa
   732301 aaatctactt atcaactcat attcactact atctattatt ccatttgaac ttgttatagt
   732361 tatataagac atagaaaata ctcatctaag tgaattctta aaagttgata ttaattggaa
   732421 aattgataaa aatcttttag tttcataaca agtattaata caattaatac taaaatagta
   732481 ttcattctaa taataacatc aaagaaacta tgaaaaatag agtgtgaatt aacactagta
   732541 gaatagaaat ttatagtatt tatttttcaa acttctcttt agttattctg agataaaata
   732601 atattgatca ttattttgtg aaactaacac aatcaaatat tcgtttactt taaccatatt
   732661 attatgcaaa ttattcacac tttttatctg acttattgta gtgttaaatc gatgagcaat
   732721 cttacttaga ctatcaccat aattaatcta ataatatact tatcttactc tattactttt
   732781 taaatattta gacaaatttt ctttaaaaat tgcaacttta tcaacctgta acagcaaatt
   732841 ataagaatcc tcatttgatg ttgcccagcg tttaagtcct ggatttaaag tatataacta
   732901 ttctaaatat agttctatcc attcagaaat taacactaaa ttaaatcgcg aatcaagctt
   732961 aatagcttaa actttaaaca gtttattaag gttttttaaa tacttaatta atctgctgcc
   733021 ttagttaaaa caagtatatc acgacgatcg tcataccaca aattattttc taaactatag
   733081 agtttttcag tcaaaagaat aaactgcaac aaacctgaaa ccataccatg taaataagaa
   733141 aatggataat aagctgattc aataattggc attaaagcaa tctcaatcag taatccagca
   733201 cgttctactt ctgtttacta aatacaaata ggcccgtgta cgcttaataa tacgcgttaa
   733261 atagtcagga ttttttaaac caatcaatat gccaaaacta gggtacgctt aacatataac
   733321 aattggaaat ataacacccc agatacttct caataaccaa gttattaata gtactaattt
   733381 gtataggatt taacactact tttataagag tgtttaaaac tatagtaccc tcacaaatac
   733441 caaataatag gaaaaaatag tttacaaaaa tttaagatgt tgaactacct acacatttag
   733501 gtgaatctgg tacaccattt ttcatctgcc actcatcaga tgtataagta tgtattgata
   733561 atgcatgaat ataagtcatc tcttctttaa ataattggtt aataaaacga tgcctttcaa
   733621 ttagttttaa atcatcaaaa taatcactca ctacaattaa cttaaaatga gattcactac
   733681 taggaccaga atggttatga gattcattaa aaacctcaag ataacttgga cttaatgcta
   733741 tttgtaattg ttcagttaaa tgttgttgca tattattcat atcacactac cttcaaaaaa
   733801 aattcaaaaa tatcagagaa taaatcttct ctaaacatgt cttgtttcac taacaagggt
   733861 cacaagaata aatcttataa tttactaaac tatcaaagtc agccaataca ccttagtaca
   733921 tatagcctac tttcaccttc caagtattat ttgcttgtga taatataggg ataaggttaa
   733981 tgtttttatg gtttttaacc tattgtttag ataaatcaac aaatctatct catctcttac
   734041 acctcaataa atatatatta ttctcttaag tttaatatca attacacaat tgactatcac
   734101 taaataaggc taaactccgt ttcgccagct actaaaataa cgaatttttt actttttctc
   734161 taaaataaaa attccattta tgtcctttaa ttttaagtaa taataatttt tcttacagcc
   734221 ccttaaaaac aaaattagta aattttccat cttcagttaa aagaacgcga agtttaattc
   734281 aaatcactat cactaggtgc attaacaata gaaaaaacat aaagatcaaa atcaggatag
   734341 attaaatcaa tgtattgcca tactaaacat tgtaacaaaa taaagctaaa aatgtttaaa
   734401 aacaattaaa ctatatcata attaagatac ttgatacttt gaactttaca aagtaatgtt
   734461 atcactttaa tatctgcaat atctactaaa atccaactac taccaaataa acattggttt
   734521 ttactccata aactaatata tcatttataa tattatcctc agcatcatct tggaaaatcc
   734581 tacccttgaa ttgatcttca attgtaaaca tatgtttata tttaataaat ttgactataa
   734641 cattataata tagattaatg tttcattaac acttagtaat taaaagcttt ttatgccaat
   734701 ccaaatcaac aaaactgtga tatttttaat gggacctacc gcctcaggta aaactaattt
   734761 agctattaaa ttaagccaac aatttaaaac tcgtcttatt agcgttgatt ctgctcttat
   734821 ttacaaagga atgaacattg gcactgcaaa accagataaa gcaactttaa aaaaatatcc
   734881 tcactactta attaatattt gtagtccaga aagttcatat tcggtctttg attttatacg
   734941 tgatgctaac aaacaaatca aaactgcttt tgctaaaaat gaattaccta ttttagtagg
   735001 tggtacctca ttttattttc atgtactaga acacggatta tccaatttac cagaatcaag
   735061 caccaagtcc aaagaaaaat tcaaccaatt acttagaaat aaaggtacaa tcaaactaca
   735121 ccaagacctt aaaaagattg accctcaagc agctaataaa attcacccaa acgattcaca
   735181 aagaatcata cgtgcacttg aagtatttaa cctgagtgga aaaacaatta gtgaattaca
   735241 aggcaataaa aaacctatta ttgactatcc cattaaaaaa atcattctca tgcccaaacg
   735301 aaacgagcta catacaaaaa ttgaaactcg gtttttatta atgatgaaga atgggttttt
   735361 aaacgaagtt caacatctta aacaaaatcc aaacctacac caaaatttat cttcaatccg
   735421 ttgtgttggt taccgacaag catggcaata tttaaacgga aaaatagata aaacagaaat
   735481 gatagaaaaa atcatcattg ctactcgaca actgtgcaaa cgccaaatca cttggctaaa
   735541 aagtgaaaaa tacgccttag ttttaaacaa ttccaatctt gctaaagcag tcacattcat
   735601 caactcataa aatacatcta agaatagttt tgatttacac ctagcaatag tcaaagaaat
   735661 agaacagact atctcttaga tttttatttt tctcaccaat aaaatatact tctcataaga
   735721 tccatctttt atattaatca aagctatcct aatagaactt tttaaaatct aaattaaact
   735781 aaatacaatc tttaaacaca cgtcctctat gctcaaaatt atcgaacata tcaaaactag
   735841 cacaccctgg agataataga attacaccgt tactaatcat tgaacgagca atattaacag
   735901 cctcttgcat ggtattggta ttggcataga taatgctgtt agtgttaatt tcttgcaaaa
   735961 attggcgagt actttgccct ataaggacaa ctccagtaat acccttatta atgaatttaa
   736021 ataataaagt gtagtcttct tttttagcaa taccacctag aattaatacg atattttgat
   736081 gtttatacat taaagtttga attgctatta tggtagagat tgcgttagta gcttttgaat
   736141 cattgtaata atcaatgttt tgttttttaa tcacccattc aagtcggtgt tctaatgctt
   736201 taaaattttt aatactttgt atcatagacg atattggtag ctttatttga tctcctaaag
   736261 caagagctgc aagtatgttc tttgtattgt gttccccaat tagttgtact tcatcaacac
   736321 tcatcaatgt attattacct ttaagtaaat aacaaatgtt gtggcaagta accgtaccaa
   736381 aatcatttgc tcttttaggt atattaatac caaaatattt aacattagtt tgtttaggaa
   736441 taagtggttc gtctaaatta actaccgaat attggcaata ttgatataga cttaatttag
   736501 aatgaatata atactcaaaa cttgagtatc gatcaagatg atcaggagta atgttaagaa
   736561 caacacctgt tattagattc aagtgatagc tgtaatctaa ttgataacta gataattcta
   736621 atacgtaata ttctattttt tcatttaaac aatccagtgc aggaatacca atattgccac
   736681 ctatagcaac tagcatacct gaatcagcaa tcatttgtgt taacaatttg gtcacggtgg
   736741 atttgccatt agaacctgta ataccaatga caggtgcttt tgcaaatctt gaaaataatt
   736801 caatatcact aacaatagga atgttttttt tcattgccca accaacaatc gtttcactct
   736861 gagcaatacc aggagaaata aaaacctcat ctacttctat tagtaaactt gatgtccata
   736921 ttccaagaat gggttttgat ttaaaaagta agctagtata tttagataaa aaaggcggat
   736981 tcatacgact atcagcaatt ttataattaa tattttgttc tgatagaaaa cgggcaattg
   737041 agaatcctgt ttttcctaag cctaaaatca atttcatata gctattttct ctgtaacata
   737101 actcatattt tatactttca aatacgaggc atcattcatg aatacaaacg ttaatactca
   737161 aatacgtgat actaatatta atagcatttt aagaaatact taccaattac tatctgcaac
   737221 cttgttattt agtggactaa tggcttattt tgctatgtct ctaaacctgc caaactttgg
   737281 ttttctaatc actcttggtg gttattttgg cttgctatat ttaaccaata aatttaaaaa
   737341 ttcaagttac ggaattttag cagtattcgc attaacaggc tttatgggac taacattagg
   737401 acctattatt agtgcttata caacaacttt ttcaaatggc tctgaactaa ttgctatggc
   737461 aatgacaggt acgggtctta tctttttatc tttgtctttt tatgctgtta cttcaggtaa
   737521 agattttagt tttttatctg gtttcttaac agcaggtgtc attgtagcat ttttagcagg
   737581 aattgccgct tacttttttg ctataccagc attatcatta actgtatctg tggcatttat
   737641 tttattaatg agtggattaa ttttgtttga gacttcaaac attatccacg gtggtgaaac
   737701 taattacatt atggcaacag taacactgtt tatttcaatt tataacttat ttttaagttt
   737761 attgcagttg ctaggagtgt tttctggaga agattagttt ttaacaaaaa aattaattga
   737821 attaatagcc gaggggatag cgaactaata ttggcattgt tattaataat gataaacaat
   737881 aattctcagt aaatacttta aacaagatta ttggtaatta tcattttaac tagaataagt
   737941 tggacgcttt ttttcgagat ttatctgaag aagctgaata ctgtatatat aaacgttctt
   738001 aataaaatac taaaatagct atgctacgat ttacttgatt atcatattag acataaacca
   738061 aaatttatat gtatctatca aaacaaaata agtttagtga tttgttacat tttaccccag
   738121 atgacaaaat atcacactct cacaaataga agtttgatag ttagatatga gtaaactatt
   738181 aatacactat tgaaaatagg attaactttg aattaataaa ttaattaccc tttaataact
   738241 aatgtacaca taaatatcct gtgagtataa tgtactattt gattgtattt aatataggaa
   738301 tgttgcttgt gaatattgga attttaggac taggcactgt cggtggtggt gtagtaaacg
   738361 tattaaataa aaaccaaaaa cagattatac gtcgatctgg taataatatt aatgtaactc
   738421 atgcagctgt gagagatata actcaaacac gaatctgccc tactaaaaat attaaactta
   738481 ctcaggaccc gtttcaaatt gtaaataatg atgatattag tgtcgtttta gaattaatgg
   738541 gtggtgtagg attggctaaa aacttaatcg aacaagccat taaaaacgga aaacatgttg
   738601 taactgctaa caaagctcta attgctacat atggtaacga attgctagcc ttagcaaaag
   738661 attacaatac acatctttta tttgaagcag ccgttgctgg tggtattcct attttaaaat
   738721 ctttgaagga cggtttaagt gctaatcaaa ttgaactagt tgctggcatt attaatggaa
   738781 caagtaactt tatactaact gaaatgcata acaaagacag aaattttcag gacgccctta
   738841 aagaggcgaa agcacttggt tatgctgaag ctaaccctac ttttgatgta gaaggtattg
   738901 atacagcgca taaattagca attcttgcct caatggcatt cggatgtgaa ttacaattca
   738961 atcaaattac aaccgaagga attagcaata ttagtagcga agatattact tatgcaacta
   739021 aactaggtta taccattaaa catattggaa ttgctaaaaa actaaatgat aaattacaaa
   739081 tgcatgtgcg accaacttta gtacctacaa cacatttact atctaatgtt aatggggtaa
   739141 tgaatggtat attaatcaaa ggaaatgcag ttggtgaaac actttactac ggtgctggtg
   739201 ctggcgatga agcaacggca agtagtgtta ttgctgattt aattgatatt atcagaaata
   739261 ctgcaaacca tgatattttt ggttggaaat cattaataaa tattacaaag tgcaatacta
   739321 atagtattgc aagtattttc tacttgcgtt tattagtcac taataaatca gggattgtaa
   739381 aagatattaa aaaaacttta gctaattatg atattaatat agaagccatc cttcaaaaga
   739441 aaattaacca gaaaaatgat ttacatattg ctcttattac taaccttact aataacagta
   739501 aaataaacaa agcagtaaca gatattcaaa aatatgatta tattatagat gagattaaaa
   739561 taatttttgt tgaaacactt aattaaggag aatataatga gatatacagg tttaattgaa
   739621 tactataaag atagactccc tgtaaatgat aatactaaac ttattagttt aggagaaggg
   739681 aatacaccac ttattcagtt ggtaaattta cctaaagaat taagtaaaga tgttgatatt
   739741 tatatcaaat atgaagggct aaatcctaca ggttcattta aagatcgcgg tatgactatg
   739801 gcagttacta aagctttaga gtctggctct aaagcaatta tttgcgcttc tacaggcaat
   739861 acttcagcat ccgccgcggc ttacgcagca cgtgctggta ttaaagcgtt tgtactaatc
   739921 cctgaaggta aaattacact aggtaagtta gcccaagcaa tgatgcacag tgctattatt
   739981 attcaaatca aaggtaactt tgatgatggt atgcgtttgg ttaaagaagt atccgaacat
   740041 gtctctgtat ctattgtcaa ttcaattaat ccgtttcgtt tacaaggtca aaaaactgct
   740101 gcctttgaaa ttatagaaga acttggattt gcaccagatt atcattgtct acctgttgga
   740161 aatgcaggta atatttcatc acattgcatg ggatattcag aattatataa agaaggaaaa
   740221 gtaaacaata tgcctaaaat gataggctat caagcagcag gatctgcacc ttttgttaaa
   740281 ggaattatga tagataaccc tgaaactatt gcaactgcta ttcgtattgg gcatcctcaa
   740341 aactgggatt tagcacaaaa agttaagaaa gaatcaaaag gatggtttag ctcattaact
   740401 gatgaaaaaa ttttaagcac acaaaaatta ctttctgaaa gagaaggtat tttctgcgaa
   740461 cctgcttcag caaccgcact agcaggtgca atccatgata ttaaaagcgg taaaattgta
   740521 aacggttcta aaatcgtatg tacactaaca ggtcatggtt taaaagactc tgatacagca
   740581 atttcacaat gcaataatca aataatcaat attaacccag taataagtga agttaaaaac
   740641 gctatttaca acaatatgta actccaacta aaaaaagtta tgatattcaa aactattgaa
   740701 caaaccattg gcaatacacc tttagtaaaa ctacaacgtc taaaccctaa ttcatcaaac
   740761 atcatcttgc tcaaactaga aggtaacaat cctgcaggat cagttaaaga tagatctgta
   740821 cttaacatgg ttttaaatag tgaaaagcga ggtgaaatat ctcctggcga taccctaatt
   740881 gaagctacca gtggtaatac tggtattgca ttagccatga tagcagctat taaaaactat
   740941 aaaatgattt taattatgcc tgattatctt tcacaagaga ggcgtgatgc catgagtgct
   741001 tatggagcca aacttatctt agttactaag gatgaaggca tggagggtgc tagagattta
   741061 gctgataaaa tggaaaaaca aggtataggt aagcagctta atcaattttc taacctagat
   741121 aatcccaatg ctcacttcaa tacaactgct gaagaaatct ggcaagatac acaaggatca
   741181 atcactcatt ttatctctgc tatggggact actggcacta ttatgggcgt atcagatagt
   741241 ttaaaagaaa aaaactcaac aattcaaatt attggcgttc aacctgaaga tggtgcacaa
   741301 attgctggaa ttcgccgttg gccaaaaaca tacttaccaa aaatttttaa tctctctaaa
   741361 gtagatacta ttatgaatat ttcacaaatc tcagcagagc agaccacacg aaacctagca
   741421 acaatagaag gtatttttgt tggtgtatcc tctggaggtt ctatattttc agctattgaa
   741481 ttatccaaaa aaattaataa cgccactatt gttactattg cttgtgaccg aggagatcgc
   741541 tacctttcaa ctggtctatt tagttgataa gatacctctc tcaccaactc cctagtaaac
   741601 taaaaattta tatattctta gcactgagca gtattattac tattattgtt attgatttct
   741661 tcctcactta tagtgaacat gcccagaaca catttaagca tttaatttct tcaaagcctt
   741721 atttaagttt tgttatcaca cctgttgttt ttgtcttagt tgtgtatatt actaagtact
   741781 tttgccatta tgttcaaggt agtggaattc cacaactaat tattgccaat gattctcgca
   741841 ataaatctat acgtaaaaag ctcttatcat ttagagtggc aactggaaaa attatactta
   741901 tttttgcagg catgcttggt ggtgcaccta ttggcattga aggacctagt attcatattg
   741961 gcggttcaat attttttgga tttaataagt tcatcaaatt taaacgtaaa ctgcttatcc
   742021 attcacttat tgcaattggt ggtagtactg gacttatcat cgccttcaac gcgccaattg
   742081 caggttttat gtttagtttt gaagaaatag gccgtaaact aaagaaacaa gcacttattt
   742141 taatcgccat cgttagtgga ttggtttact tattagcaat tatatatcgt ggtaatagta
   742201 tctatttgag cgatatgtca gccaattcta ttgatttaat actaatttgg caattactac
   742261 cattagtaat attatccggt atttttggtg gtttattctc aaaaacaact ctttacttga
   742321 ttaaaatatt taccgcttac accaaaatta aagttattat gattgcatta atattaggct
   742381 taattattgc actatttaat tatttatctc aaggtcagat tgctggttcc ggtcgtgaag
   742441 aagtattgtt aatattagct ggctatcaat ttgataatga ttttattgtg atgaaatatt
   742501 tatcaaccct aagttcttta gcctccacca ttcctggagg gttatttatg cctagtattt
   742561 ctatcggtgc tggtattggt agtgaaatga gcaattatta ttcacaaatc aatccacaaa
   742621 ttattatcat tatgtcgatg attgcttatt taaccgctgt cattaggacc ccacttactt
   742681 gtacatttgt cattttagaa atgacaaata cacttaattt acttattcca gcattgattg
   742741 tcgcttttat tgctaattgg atatctaaac aaatatccaa acctccaatc tacgaggcat
   742801 tggctaataa ttacttaaag ttaacgcaaa aaactaaaac ggtttaacca caacaagtac
   742861 aacaacaccc actaatatta atacaggaaa ctcgttaaac caacgataaa aaacatgaga
   742921 tcgagtgttt tcatcagcct taaaaacatc cactaaatag ccacaaaaaa aatgatatac
   742981 tatcaacaac attactaata ataacttaac atataaccaa tattgaattg aataatatgc
   743041 ccaaccatca atgcttaaac ataatcctaa tacactagct agtataaaac tcggcatcat
   743101 aatacctgta taaagcttat attccatcac tttaaaacga tcaatactga gcttgtcttg
   743161 actcattgag tggtaaacaa aaagacgtgg taaataaaac agtgatgcaa accaagtaat
   743221 aacactaata atatgaaaag cttttatcca caacatgcac aaccgaccct tattaaagtt
   743281 ttttaggatt aatatacatc atttaaacat caattacagt catataaatt tacttcgata
   743341 tttaattaaa acaaaataat gaaactccct acaactacat attctatttt ggtaaataaa
   743401 ttgtgtatcg ttttttagat gttaataaca tcccttaatg agaatgtaat tattcaccta
   743461 aataaactga tatattataa taatgacatt gaataaacta atattagttt attcaatagc
   743521 aataaaattg ctaccatagc tgtatagtta aaggttattt taaaaatcta aaaccaaaaa
   743581 ataatattga ttaaaagcat gattaaatta tactttcgtt attgtaaata caagaatgta
   743641 tatactaaat acatattgta aggaaattct ttatacttca tcatacgata aatttattga
   743701 tactaaataa gattatataa cgaataaaat agtaactctc attgataata tattatttaa
   743761 tatttacaaa atgagtttaa tttcttatca cacatcgtta aatatgcaaa aatttcactt
   743821 tgataaaaat aaaagatagt aaaattaatt tttttatact ttaattatta tgtttaattt
   743881 tttaaaaaaa aatcggtcaa aatcagaaaa tttaggcaca aacaaaccaa cttcattaaa
   743941 gcaacgccta gataaatcta gacaaaaatt aggatatagc ttatcttctt tattgttggg
   744001 caaaaaagaa attaatgaga atttattaga agaactagaa acactattaa ttactgctga
   744061 tgtcggtatt aataccacag ataaaataat aaaatctaca cgtaaaaatg cttctagaaa
   744121 aaccttaaaa aatgctgaaa gcttgtatca atttttaaaa gatgaattgg ctaaactatt
   744181 cattgaaaac aaccaactta atattagtat taatgaaact tttgttattc tagtcgtagg
   744241 tgttaatggc gctggtaaaa ctaccttgat tggtaaatta gcaaaatctt ttcaaaatca
   744301 aggcaaatcg gttatgctag cagcaggcga tactttccgc gctgcagcca ttgaacaact
   744361 aaaaatatgg ggacaacgca ataatatccc tgttgtagca aaaactttag gtgctgatac
   744421 tgcttctgtc atttttgatg cctaccaatc agcacaagcc aagaatattg atatcctgct
   744481 tgctgatact gcggggcgat tacatacaca agacaatctt atgcaagaat tagctaaaat
   744541 taaacgcgtt attaccaaac aaaatataaa tgcgccacat gaaactatgc tagttattga
   744601 cggaggatca ggacaaaata tcatcaatca agctaaagag tttaataagg cagttaatct
   744661 aagtggtatt agtataacta aactagatgg tactgctaaa ggcggagggt tgttttcgat
   744721 tgctgacgaa ctcaatttac ctattcgcta tattggcata ggtgaaggga ttgatgatct
   744781 taaaattttt caacctaaag aattcataaa cgctttgttt gatcaataat acaattatta
   744841 taagtttaag ctattatatt aaataatttt agaataatta gagtgaaatt atatttctaa
   744901 tattttattc aatacacaac atagccaatg ttattttaaa cataataaaa aattttaaaa
   744961 cgacaatagt tatacctatc atttattcga ctttaacgat gccaattttt aatagattac
   745021 cttatattat ctaattaact tattcttcaa atatttggtt atatcagtat aataaatttt
   745081 cagtgttaag catctacata attaattttc taaaaatttc acaaaagcca attgcaatgt
   745141 tttttatata aggattaact ttgaatctaa attatatgcc tattttatta aatacttcgt
   745201 caaataattt tttcataacc aactactatt cataaaacca atacaaacaa tgaaccaaaa
   745261 cattgcacaa taatcaaaga gtttttctta ataaaaacta acatattaac ttgcttatat
   745321 aatcaaaaat atcaataatt tattggctaa ttcaatattc aattgagtaa ttaagacttc
   745381 gttatatatg attaaaccaa tcataacaat tatatgaaca tttgacaaac tatagataat
   745441 gatttattat caagatcttg ataataatct gtgttataag agtagaagcc taagtaaaat
   745501 caatagaaac aaaaatttag ttaaatttat cattaaacaa catctttaaa tcaaattatg
   745561 tattttatat tttaatcttt tagaatatcc tttgccccta ataatatgag tttatttgcc
   745621 aactcaatac ccaaaatttc tgcttgagaa acatgaccaa aaattttctc ttttaatatc
   745681 acaccagtat caatattacc tactaaacct gttaacgtta tttgcttatt attaattgtc
   745741 gcaaagccag caactggtac cgaacaacca ccctcaagtt gtgtattcat tgcccgttct
   745801 gcaattattc tataagaagt ctcaatatca atcaaaggtt taattaagtc taagatttcc
   745861 ttatcatttt cacgaatctc aataccaatc gcaccttgac caaccgctgg aaggttttga
   745921 ttctctggaa tttgttgctt aattctattt ccaaaaccta aacgaataag ccctgcacaa
   745981 gcaagaataa tggcatcaaa ctctccatca tctaattttt ttaatcgagt attaacattg
   746041 ccacgcaaat ctataatttg caaatcaggt ctgataactt taagttgcaa aatacgacgc
   746101 attgaacacg taccaacttt agcattcttt ggcaaatcat caatactaga aaaatgatta
   746161 gaaacaaaag catcaaatgg gttttcacat tttaaaattg ctcctaattc aaactcttgt
   746221 ggtatttcat aaggaacatc cttcatagag tgtacagcaa tatcactcat gcctttcata
   746281 atactaattt ctaattcttt aataaataag cccttaccgc caatctttga caaagatgaa
   746341 ttcaaaattt ggtcgccttt agtagttatt ttcaccaaaa taaccgttag attaggataa
   746401 attttttcta atctagattt aacatgttgt gcttgccata atgccaatgg agattgtcga
   746461 gttgcaattt tcagggtttt attcatggtt aaaagagttt atattaaaat agctatatgt
   746521 ttcatatctt atctattatt acttgtgttt atttctaatt tttctgtatc acaagattta
   746581 acagaaaatc tcttaaaaga tgctcagtta gtacgtaaag ataaaacaaa tactttaata
   746641 aagtcttccc ttcataataa tcgttattat ccagaaataa aacaaaaagt cattacacct
   746701 ataaataaat taggtgaaca taaaaataat actattattc tccatgttaa tactaataca
   746761 ctaaaaaaca taaaggattc taacaataaa aacactaatc aaaatagaat taattcttat
   746821 cctacagtat tctttataga caaatttagt acaaacttat acaaaatagt taagcacatc
   746881 tagaataggt tattattaaa ccgaacttaa taaagtagtt aacaaatcaa tcactaaact
   746941 taaacaataa aaggaaagat gatgaacaac aaaacacagc aaaaacaaca cacagtagtc
   747001 cctaagaaaa aatctagaca gataacacaa actaatcaat cttggggtgg gcgttttaaa
   747061 gaaccaacag atgagtttgt taaaattttt agtgcatcaa tattttttga taaaatttta
   747121 gcaccttacg atattcaagg ttcaattgct cacgccacca tgttgcaaga agttggatta
   747181 ctcactaaat atgaaaaaaa tcaaatcatt aaagggcttg ataagattct aaataaaatc
   747241 aaaactggtg aatttgagtg gtcagtaaca cttgaagatg tacatatgaa tattgaggca
   747301 tatttaatta agctgattgg agatacagga aaaaaactac acacaggacg ttctcgtaat
   747361 gaccaaatag caactgatat ccgtctttat ttacgtgacc aagttgatga tattattaga
   747421 aaaattaaac gtttacagct agtattaact aatttagctg aaagagagat gagtacaatc
   747481 atgcctggct ttactcatct tcaagccgca caaccaatca gttttggcca ccatatgatg
   747541 gcttattttg aaatgttagc acgtgatgta gaacgcttat ttgattgtcg taagcgcatc
   747601 aactcaatgc cattaggttc agctgcatta gcaggtacca cttatcccat taaacgcaca
   747661 cgtacagctg aattattggg atttaaacgt atttgtctta attcacttga tggcgtgagt
   747721 gatcgagatt ttgccattga atttttatcc atagcaagca taatcatgat gcatctttca
   747781 cgtttttcag aagagttaat tttgtggtca agtacacaat ttaactttat cgaattacat
   747841 gatagttttt gtacaggttc atccatcatg ccacaaaaga aaaacccaga tattcctgaa
   747901 ttagttagag gaaaaacagg acgtgtgtat ggtaatttaa cctcactcct gactattatg
   747961 aaatcccagc cactggctta taacaaagac aatcaagaag ataaagagcc attattcgat
   748021 acggttgaca ctttaaaagc ttgtttacgt gtctttgcag acatgatacc aaccattcaa
   748081 ataaaatgtg acaatatgta taactcaact aaacaaggtt ataccacagc tactgattta
   748141 gccgattatt tagtcaacaa aggcttacct tttagagatg cgcatacagt agttggaaaa
   748201 tcagtttctt atggaattaa acaccaaaaa gatttaagcg aacttagttt gaaagaacta
   748261 caaatctttg atagtcgtat tgaaaatgat gtatttaaag tgctatcact aaaaggttcg
   748321 ttaaatgcac gtaatcattt aggagcaaca agcccaaacc aagtcaaaca aactattaaa
   748381 atagcaagaa aaggtctaaa ataatgcact ccaaaagcac ttcttttaag actcgtatag
   748441 cctttgcagg tacgactaag ttttcagtag ctatcttaga aatactaatt aatgccaaat
   748501 atgatattgt tggagtatat tgccaaccag accgccctaa aggtcgtgga agaatcttaa
   748561 cagcctgccc tgttaaagaa aaagcattag aatataactt aaaaattttt caacctgaaa
   748621 acttacaaag caccaaaact caacaggcct tagctaagct taatgcggat gtgatgatag
   748681 tagtatctta cggacaaata ttgcctgaga gaattctcaa tatgctcaaa tatggctgtc
   748741 ttaatatcca tagctcatta ttaccacgct ggcgtggtgc agcacctatc cagcgtgcaa
   748801 ttttagcagg tgataaaata acaggtatca gcattataca aatgaataag attttagata
   748861 caggagatat attacttgaa aaaaattgta caatcacgct taacgataca acacaatcct
   748921 tacataataa actggtcaaa cttggctcta atgctattgt tgaagtccta aacaatcttg
   748981 ataatttatc accaacagaa caaagtaaaa acaacatcac ttacgctaaa aaactcaaaa
   749041 aaaacgaagc ttggattgac tggactcaaa gtgccataca aatccaccag aaaattagag
   749101 catttaaccc ctaccctatt acccaaaccc atgcatcaag taatagattt gctactaaaa
   749161 ttctacgtat tttttctgcc tctatagtag tgactaacga taattacagt ccaggaaata
   749221 ttattaaaca taacaaaaag atatgtatcg ttgccactgg agatggtgcg ctaagcctag
   749281 aaactgtaca actttcaggc aagaaagtgc tcaatattaa agattttagc aatgcttata
   749341 aacttactaa actatttatt acttgcagat agaatcactc tcaaaatatt ttcaaatact
   749401 atctttaatt tgttttagta tatctaaaat taataccttt gttttgcctt gaatatcaaa
   749461 tatcttatat tgtaaatact attcgagtct gctatcaagt cagaaaagtg gtgatactac
   749521 taacaaaagt acatattaat acaataaatt taacataata cttgaaaagt atcaatcatc
   749581 ccatagataa tttttatata ttataaagaa tatgatttct atgaattttg ataaactaac
   749641 tgcacaattc caacaagact taagtactgc acaatccata gctattacaa aaaatcacag
   749701 taccatagaa gcagtacata ttataagtag tatgttacaa aataataata gtagtgttaa
   749761 taatttatta tcaaacattg atattgatat tcatcaactt aaacaagaaa ctgataaaga
   749821 aattaataca ttagccacga tcagcaatcc aagtggtgat gttaatattt ctcagaactt
   749881 gttacgttta ttaaatcaga tggaaaaatt agctctcaat aaaaaagatt cgtatctatc
   749941 aactgagata tttttattgg caatcataaa aggcaatgat acaactacaa aacttctaaa
   750001 agcacatggt gtaaatgaga ttaatttaaa tcaagcaatt gacaacctta gaggaggtaa
   750061 aaacgtgaat aatcaaaaca cagaaaataa ccaaaatacg ctaaataaat acactcaaga
   750121 tttaactcaa ttagccattg atggtaagct tgaccctgtg attggtcgtg atagtgaaat
   750181 tcgtcgtgct attcaagtat tacaacgaag aactaaaaat aatccagttt taattggtga
   750241 acctggtgtg ggtaaaactg ctattgttga aggtttagca caacgtatta ttaatcatga
   750301 agtatcagaa ggtatcaaag gcaagcgtgt tttatcgcta gacatgacag cactgatagc
   750361 tggtgctaaa tatcgaggcg aatttgaaga gcgactaaaa gtcgtactta aagaattaga
   750421 agacaaacaa ggtcaaatca tcttatttat tgatgaatta cacaccatgg ttggtattgg
   750481 caaatccgat ggttctatgg atgctggaaa tatattaaaa ccagctttag ctcgtggtga
   750541 tctacactgt ataggcgcta ctacactaaa tgaatatcga caatatattg aaaaagattc
   750601 tgctttagaa cgtcgcttcc aaaaagtatt agtagacgaa ccaaccgaac aagacactat
   750661 tgctatttta cggggtctta aggaaaaata cgaagttcat catggtgtag aaatcacaga
   750721 tcctgctatt attgtcgctg tcacttattc aaccagatat attactgaca gacaattacc
   750781 agataaagcc attgatttga ttgatgaagc agcctcacaa atccgcatgg aaatcgactc
   750841 aaaaccagaa tcaatggata aacttgaccg taaattagtg caacttaaaa ttgaacgtat
   750901 ggcactcaaa aaagaaaaag acaaagcttc taaaacacga ttagaagaat tggtaaagtt
   750961 gattaaatca ctagaaaaag agtacgctaa tttggaaaaa atttggaaaa aagaaaagct
   751021 agtagtccaa agtgcacacc atcttaaaga agaactagaa caagcaaaat ccgatttaga
   751081 aaatgcacat cgtaacaata atttagccaa aatgagtgaa cttcaatacg gaattattcc
   751141 tgaattagaa cagaaaatta acatggctga aaatgctgac acagaacaaa tgacattact
   751201 taggaataaa gtcactgaaa atgaaatcgc ccatattgtt gcccgttgga caggtattcc
   751261 tgtggataaa atgatggcag gtgaaaaaga taagctacta cagatggaaa ctattattca
   751321 caaacgccta gttggtcaag ataaggctgt taaagttatt tcagatgctg tgcgtcgtgc
   751381 gagaagtggc ctatctgacc ctaaccggcc tgatggttcg tttctattta tgggccctac
   751441 tggtgtggga aaaactgaac ttaccaaagc cttagcagac ttcttatttg atacagaaca
   751501 agctattgta cgtattgata tgagcgaatt tatggaaaaa cactcagttg cacgtttgat
   751561 tggtgcgcct ccaggatatg ttggttatga acaaggaggg gtattaactg aagctgtgcg
   751621 tcgcaagcct tattcgatca ttttacttga tgaaatcgaa aaagcccatt cagatttgtt
   751681 taatatttta ttacaagtac tagatgatgg tagactaacg gatagtcaag gtcgaacagt
   751741 cgattttaaa aatactatta ttatcatgac ttcaaaccta ggttctcact taattcaaca
   751801 aaacccagga aaagatatgt ctgttgaact aactaaaatt gttagtgaac acttcaggcc
   751861 tgagtttgtc aatcgtattg atgagatcgt aacctttaaa acactagaaa aatctcaaat
   751921 taaaggtatt gcactcaggc aaattgagat cttatcatca cgtttatcca agcttaatct
   751981 tagaataaca ttaagcgaca tagccataag tatgattgtt aacaaaggct ataaccctgt
   752041 gtttggcgcc agaccgctca aacgtaccat acaacaatta ttagaaaatc cattgtcaaa
   752101 aaaaatcatt gctggagaat ttttatcaga ctcaactatt catggagatg ttaaagatgg
   752161 aaaaatcgtt ttctattaat cgatttttat ctaatcaaaa ccctactgct attaaattga
   752221 catttaatta agtatataat taaacattat gtgcaactat aataaaatta taaaaaatgg
   752281 actatggaat aacaatcaag ccttagttgc tattttaggt ctatgtccct tattagcagt
   752341 cacaaataat attgttaatg cagtcggact tggtctagca actacatttg ttttagtaat
   752401 gtctaatgta actgtttcta tttttcgtca tcatatttca aaagaaattc gtattcctgt
   752461 ttttgtccta ttgattgctt catttgtaac aattgttgaa ttgataatgc agtcatattt
   752521 ttatgacttg tatttgatat taggtatttt tgtaccgcta attgtaacta actgcgctat
   752581 tttaggacgt gctgaggcat ttgccagtaa gaacacttgg gataagtcta tactggatgg
   752641 attaatgatg ggtattggtt tctctgttgt gcttattata ttaggtgcaa tgcgtgaatt
   752701 aattggtaat ggtactttat ttgataaatc tgtattatta ctgggtgatt ttggtaatac
   752761 acttagtatt actgtgtttg aaaattatca aggcacttta ttagctattt taccaccagg
   752821 agcatttatt ggtttagggc ttattatagc aatgaaaaat aaatacgatt tgaaaagaaa
   752881 aaaattataa acaaataaac caatcgcgga aagattataa taaatgatat ttttaaaccc
   752941 cgcactgtag gaacaaatag caaatttaac atgattcact acgttaaata aaaatcagta
   753001 agtgaatatg atatacttat ccttggttta tgatatataa atacactaat tatataacta
   753061 ttacaagtgt ctctcctacc attattagca cattctttat acacatttga aggataaagc
   753121 aaaagcatta gaatttgaca atcattaatt tacaaacctt ggatactatt caaaattatt
   753181 taagcagtga tataattgat atagtacttc tactatctct aactcttgat aaaagccatg
   753241 ctcaacttat ttctcataat aattatcaac taagtagtaa cgaaaaaaat caactcaatc
   753301 aattcatcaa acacagacag tccggtgttc catttgctta tttaagcgga acaaaaggat
   753361 tttatcatct tgattttaaa gttactcctg atacgctcat ccctagacct gaaactgaac
   753421 tattaattga cattgcttta ggcttgttta atcaaaatca aacttatgaa gtacttgatt
   753481 taggtactgg tagtggagtt attgccataa caataagtga taaaaatcca aactggaatt
   753541 taaccgcaac tgatttttca atcaatgcac ttgcagttgc taaacaaaac acaaaaacaa
   753601 atattaattt tcaactaggt agttggtttg aagctacccc taatcaaaca ttcgatttaa
   753661 ttatctccaa cccaccttat atcaaacaaa atgatattca tcttaatgaa ttaagatttg
   753721 agccacaaag tgcgcttatt tctggcaaag atggtttaga tgatattcaa attatcatta
   753781 ataacatacc aaaatttctc aatgagaaag gctatctatt attagaacat ggtttcaatc
   753841 aacaacaaaa aatcatacaa ttattaaaag ataatttttt caacattaaa aaatttaaag
   753901 actataacca aaaaaatcgt gcaattttag cacaaattaa acattaacaa ttataaaaaa
   753961 ccctttccaa cgatatcatt tgcgtctcaa gaatagataa aatattctcc ttgactaaaa
   754021 ttatatatgg tagaacaata aggatattca ggtacatata atattatgca aataattatt
   754081 agttgatacg ttaaataaca ttaattgaat aattcttata aagatcatat tttacaataa
   754141 gaacaaacaa agataaaaca aaagaagtcg gtctataagc cgggttctgt aataaatggt
   754201 cattcatcta cgtgttttgt taccaaaacg ctttagcgct ctacccacaa acttcgcgag
   754261 caacgttatc gttagtctat ttgagcttac tccaagtggg gttttccttg ccacgattgt
   754321 caccaatccc gcggtgcgct cttaccacac cttctcaccc ttacctatta aaaataggcg
   754381 gtctaaatct ctgcatcact ttccgttatg tcgccatacc tagccgttaa ctaacacttt
   754441 gctctatgga gcccggactt tcctctgaag atcaatctcc agcgaccatc cgaccaactt
   754501 cgagataatt atactctaag cttacatctc taaagttctt aaattacctt aaaaaaaata
   754561 atttcactaa aatatttgcc aatttactta atggattatc ttaatatctt tgaatatact
   754621 atgaatatta ttaccttgag tatcgactgc aactgtaacc ggcatgtctt taacttcaaa
   754681 ttcataaatt gcctccatac ccatttcttt aaacgcaatt tttttagctt ttttaataga
   754741 cttagaaatt aaataagctg caccacctac tgcaataaga tacgtaacct tatgtttctt
   754801 aataatttgt acactatcct caccacgttc tgccttgcca atcataccca aaatattagt
   754861 attatccaat atcatatcgg taaatttatc catacgtgta gcagtggtag gacctgatgg
   754921 accaattact tcatcaccaa cagcatccac tggaccgaca taataaataa acttattatc
   754981 aaaatttaca ccatctggca agccttcgcc attatcaatc atttctttaa gatacttatg
   755041 cgctacatct ctcccagtaa tgattgaacc tgataacaat aaggtatctc caatatgcca
   755101 tagagccatt ttttcacgag ttaaattact tagatcaatt tttttatatt gagtatagtc
   755161 catctctaat tgaggataac tatccatatc tacctgagga agttgcgcca cacctgaacc
   755221 atcaagtgaa aaatgcaaat gacgtgttgc cgcacaatta ggaatcatcg ccaccgcttg
   755281 agaagcagca tgagttggat agtctttaat tttaacatct agcactgttg ttaaaccacc
   755341 caaaccttgt gcaccaatgc ctaaatcatt aatcttatca aataattcaa gacgtaattt
   755401 ttcaagatta cttggattag atttctgggc aatatctttg atgtcaattg gttccatcaa
   755461 actctgtttc gccattaaca ttgatttttc agctgtacca ccaacaccaa taccaataat
   755521 acctggcggg caccaaccag cgcccatagt tggtatagct tctaaaaccc aatcaataat
   755581 atcaacatct ggttcaagca tactaaactt agccttattt tcagaaccgc cacctttagc
   755641 cgcaacaata aaattaagct gttcgccttt aacaactttc atgtgaataa ctgctggagt
   755701 attatcttta gtgttaactc tagtaaataa tggatctttt acaatagaag ctctaagagg
   755761 attatttaca taagtaaatg cctgtctaac tccttcatta atcatatctt ctaatgataa
   755821 attagctatc caagtaacct ccataccaac ctcaacaaac acattaacaa caccagtatc
   755881 ttgacatatt ggacgcttac caaagactgc catttttgaa ttaataagaa tttgtgtaat
   755941 ggcatttttt gcggctttgt gagtttcttt ttcataagca cttgtcatcg cttgaataaa
   756001 atcaggacta tgataataag agatatattg caaagcatta aaaatacttt ctatgacatg
   756061 tttttgttga attttcatat ttataaggtg ttaattatta ctgattattt atagtattat
   756121 atctctttat tttacaaaaa tttaattggg aatttttatg tttaattttt taaaagggca
   756181 aagtcttgat tttttaaaag ggcaaagtct tgatttttta aaagggcaaa gtctttctat
   756241 cgacttaggt acagctaata cattaatttg tatggatggt gctgtggtac taaatgagcc
   756301 gtcagtggtt gctattcata atgatagaag atcgctagaa tcaactgtta ttgctgtagg
   756361 tcaagatgct aaaaatatgc taggcagaac accaggttct attgaagcta tcagacctat
   756421 gaaagatggt gtcattgctg attttaaaat tactgaaaaa atgttgcagc attttattcg
   756481 taaggtttta cgctctggct ttttttcacc aagtcctaaa gtacttattt gtgtaccttg
   756541 cggtgcaact caagttgagc gtcgcgctat taaagaaagt gctgttggcg caggtgcacg
   756601 tgatgtttat ttaattgaag aaccaatggc agcagcgctt ggtgcaggta tggcaattga
   756661 agaagcttca ggagctatgg ttattgatat tggcgggggc acaactgaga ttgcaattat
   756721 gtcacttaat ggtattgtat attctgactc attacgcata ggtggagatg tgtttgatga
   756781 tacaattgtc aaatttatac gtcgtgaaca cggcattatt atcggatact caactgctga
   756841 aaagattaaa gaagaggtgg gatcagcatt caaatcaagc gctgttaaag aaatgcaatt
   756901 tagaggacgt gatgttgcta agggaattcc agtaagcttc aatataacta atactgaaat
   756961 tttacaaaca ttgaaagaac cacttaaaat aattatcggt tctattaaga ctgcattaga
   757021 aaaaaccccg ccagagttaa gttctgacat tgccgaaaat ggcttagttc tcacaggtgg
   757081 tggtgcactc ttagatggtc ttaataagct tattagtcaa gaaactaatc ttccagtacg
   757141 tattgctgac gatccactta cttgtgttgc tcgcgggggt ggagttgcac ttaatatgat
   757201 ctctaaacat aatatagggt ttttagctgc tgaatagtta aatattgatt aactatttat
   757261 agggcttacc aatatgaagt ttcttgaact ttttatccct gtcattatct ctatattgct
   757321 tatactatct gattataaat tttcatatct taaccatcta agacaatcaa ttgaaacctt
   757381 aatatcgccc atctatatgg tagtaaactt accttcacag atctatattt ggattgacaa
   757441 gcaaggtact agcaaagatc aattaaccat aaataatgat aatttacatc gtgaactatt
   757501 aaaacttaaa gctaaattac aaacctataa tgccttagca cttgaaaata aaaaactcca
   757561 agcactatta ggttcaagtt ataccgtaaa acaacaaaac tttactttag cacgaataag
   757621 tgaacttagc caatctagaa ttaaaaaaca aattattatt aataaaggta gtagtagtgg
   757681 cattaaaatt ggacaaatag ccttaagttc taaaggtatt attggacaaa tatcgagaac
   757741 aacaccacta tattcaacta tattaatggc tagcgatcct acacaacacg ttcctgttaa
   757801 aaatgaacgt agtggtgttc gaggtattag caaaggtata gctaataata atcatctatt
   757861 aagcgttgaa tttatcgagc ctaatttaga cgttaaagta ggtgatgtat ttctaagtag
   757921 tgctatcgga tcaaaatttc cagatggata cccagtagga acagtaatta gcgtagaaaa
   757981 aaaccaaaac gaaccattct tacatatcca attaaaacct gctcaaatac cagaacaact
   758041 agaatttgtt attattacaa ccgactaacc atgaatgtac aacgtcgtcc ctatatattt
   758101 ctaatgaaga ttactttttt tgcattaatt ttaagtgtaa tacctctaaa taagctgtta
   758161 ttaggcgcat ctgcattttg gttattactt ctttatatct actggatagt atacttttca
   758221 accaaattaa aattttttat tgcgcttatt cttggcacac ttgttgatat tctacatggt
   758281 gacattttgg gacaaaacgc cttagcgctt atttttagta gcctatttat tagcaatata
   758341 aagcaatcat tttttttatc taacctaagc actcaacaag tttatatatt tatatctagc
   758401 agtatttatt tggtattttt cttactaatc tttgtattaa cacaaggttt tatcattaac
   758461 tattacttat ttttagctcc atttactagt gcattcattt ggccagtcgt tcagttctta
   758521 ttatcaaaat gcaaagcata aataatgttc aatttgaaaa caaaacactc ttttctagac
   758581 ttagactagc acttattttt atttttttac tcaccacttt gttaataatt agaatttaca
   758641 atttacaaat agtcaaccat caatattact taaaaaaatc tttagacaac caaatacgta
   758701 ctatgccgat aacacctagt agaggaaaaa tatttgatcg taatggtaat gttttagcta
   758761 ctaataaact agcatttcgg ctaaccttaa cacaagaaaa aactaaaaac attacgaaaa
   758821 cactacaaca actaaaacag tctggattta tcaatgataa ggatattaaa agctttaatc
   758881 agaatataaa acattatcaa aaatttcata gtattccaat tagatataat cttaatgaga
   758941 ttcaggttgc aaaattctta attagcaata tttttattgg tgtaaatata gagccttatt
   759001 tccatcgaat ctatcccaac cagaattcta gcgttcatgt tattggttat gtttctagaa
   759061 tgtctaaaaa agatcaacta atttacgata agaaaaacta tttagggact ttatttgtag
   759121 gtaaaactgg cattgagaaa caatacgaaa tactattaca tggtactaac ggcttacaac
   759181 aaatcgaacg aaatgtaaat ggtagagtta ttcacaccaa aatcattaag cctgctatta
   759241 ctggtaagaa tttatatcta agcatagact tagatatgca aaaaaaagca gaaacactcc
   759301 ttaaaggaaa acgtggttca attgtggtga tagatgtcaa aaatggagaa atattaacac
   759361 tcgttagtac gcctatttat aatccaaact ggtttgtaaa tggcatatca cataccaact
   759421 acaaccaatt acaaacatca aaaaatatcc ctcaacttaa ccgtgcaatt caagggttat
   759481 atcctccagg atctacaatt aaacctatgg tggctttagc aggtttagaa gagggggtta
   759541 ttactaatat aagcagcact ttctgcccag gttattacaa attaccaaat gttaaacgca
   759601 aatttaacga ttggaaaaaa acaggacatg ggcatgtcaa tgtcaaagac tcaatcacac
   759661 aatcatgtga tgtatttttc tatgacttag caaataaatt gggtattgac aaattgcata
   759721 ataatttaga cttgtttaat tttggccgaa agacaaatat tgatattcct ggagaaaatc
   759781 ccggaatatt accctctaaa gtttggaaaa aaattaataa acataaacct tggtatcgtg
   759841 gagagacctt gattacaggt attggtcagg gatttatagc tgttactcct ttacagcttg
   759901 cagttgccac tacagcaatt gccaacaaag ggattctatt tcaaccaacc ttgcttaaaa
   759961 atacgcaagc atctgatgat ataatcattg agtctaaaaa agatagtcat atacaaattc
   760021 caattaaaaa tattcaaaat tgggaagatg taattgacgg aatgaaacaa gctatttatg
   760081 cacctaaagg tactgctaga aagctcaata aaggtttaac ctacacatta gctggaaaaa
   760141 ctggaaccgc acaagtgttt agtcttgata atactataaa acaatatatt gaagcaaaac
   760201 ttgatgaaag attaagagat catgcattat ttactggctt tgcccctact gaaaatccag
   760261 aaatagctat cgctattatt gttgaaaatg caggtaatgg cagctcaaaa gcagcaccaa
   760321 ttgcacgtca agtacttgat gtatatttta ataaacaatt aaataatact ttgccttaat
   760381 aaattccagt caaatggaaa tattaaaatc gataaacacg ctttaaattg atctaattat
   760441 ggctaattaa ttcattatac aaaataatta ttttagcctt agatcagtcc ccttctaaat
   760501 ttaatattgc ttactctatc tctaaactat ggattgtaac taaacctcta gtcgccaata
   760561 cttagcaagt atttgtattt tctttctata agaaaacttc aaacctactg aaaactatta
   760621 ttcgataaac atcaaagtat agtcttcaaa atcaacatga tcactaaaaa ataataaatt
   760681 attactcata gagtgtcatg tccttgttgt tggtaaaatt ctttcttaaa ttttgaaaat
   760741 ttattacttt caatagctct acgcatttgt aacattaggt attggtaata ataaagattg
   760801 tgaatagtat taagtcttgc acctaagatt tcattttttc tttgtaagtg atgtaaataa
   760861 gacttagaat aattttgaca agtataacaa tgacagcact cgtctaatac tgaagtatca
   760921 agtctatacc gcgcattacg aattttaaca ataccaattg aggtaaataa ataaccatta
   760981 cgagcattac gtgttggcat aacacaatca aacatatcaa taccacgctc aactgcttct
   761041 accaagtctt ttggtgtacc aacacccatc aaatatctta acttatcact aggtaattga
   761101 cttggaagat aatccaacac ctttatcatc tcttctttgg actcacccac actcaaacca
   761161 ccaattgcaa atccattaaa tcctatttca accaaagtag ctgctgattg aatacgcaaa
   761221 tcctcatgca tgccaccttg aacaattcca aataaggcat ttttattatt taaacgatca
   761281 tgctcatttt ttgacctttg tgcccatcgc aaagacaatt gcatagactt ataaactgtt
   761341 tttttatcag cgggataagg tgtacactca tcaaaaatca taacaatatc tgagcctaat
   761401 ttcttctgta tttgtattga ctcttctggt cccatgaaaa ttttagcacc atctttaggt
   761461 gaacgaaaat ctacaccttt ttcactaatt tttcttgttt ctcctaaact aaatacctga
   761521 aaaccaccgg aatctgttaa tattggacct ttccaatgca taaaatcatg taaatttcca
   761581 tgtgcttgaa caacatctat accaggtgta atcgctaaat gaaaactgtt tcctaaaatc
   761641 atttgtgtgc caaagctgct caattcttct ggcgtcatgg ctttaactga accataagtt
   761701 ccaactggca taaatgatgg tgtttcaacc tcacctctat caaaaattat ttttccacga
   761761 cgtgctaaat aatttgtatt ttttaattca aatttcatca cttttctcat taacttgtaa
   761821 ctgccataat ttagcatatt caccattaga ctctaataac ttagcatgtg ttccactttc
   761881 ttgcactttc ccatctccaa gtacaataat tttattacta tcaataatgg tagatagtcg
   761941 atgtgcaatt actaaaatag tatgcttgct agataatatc tttaatgatt tctgaaccat
   762001 cttctctgaa taagaatcta atgccgatgt tgcttcatca aaaattaaaa taggcgggtt
   762061 ctttaaaagt actctagcaa ttgctaaacg ttgtttttcg ccaccagaaa gtttcaaacc
   762121 acgttcacca actaacgtat catagccttg aggaagctta ttaataaagg tgtcaataaa
   762181 actaagttta gctacttttt ctacttcatg ttggtttgta tcttgtttcc cataagcaat
   762241 attgtaataa atactttcat taaacattac agtatcttgt ggaacaacac caataactga
   762301 ttgcactgag tgttgattca aagtctggat attttgtcca tcaattaaga tttcaccact
   762361 atccacatca taaaatcgaa ataataattt cgccaatgtt gacttaccag aaccagattt
   762421 acctacaatc gctacttttt gtccaggctc aataacaaaa ctaacttctt ttaatatttt
   762481 attcttacct ttgtaagcaa aagaaatacg cttaaactca atctttcctt gaccaatttt
   762541 tatttttggt gcatccttag aactattcac ttttgattga cgatcaagta aatcgaacat
   762601 gttattcata tcaataaagt tatgcttaat ctgtcgatac acaattccta aagaacccaa
   762661 aggcataaat aactgtaata acaatacttg aatcataatc atatcaccaa gactcaaact
   762721 ttcatcaaca acaccttgag atgcgaaaat taaaatgata gttattccta cagcaataac
   762781 agcactttgg acgaagttaa gcgctgtcat tgaagtaaaa cttttcgtgg caatgttttc
   762841 ccaacgagtc atagtttcat cataacgatt aacttcagca tcctcttgat taaaatattt
   762901 aaccgtctca tagttaatta aactgtccac tgcattcata ttagcctcag attgcatatc
   762961 attcatctga taacggtact tcatccgcca agttgtaata accaatgtaa agcctacata
   763021 aaaaactacc gttaataatg aaataccagc aaagaaaata tcataattaa accacaaaac
   763081 accaatcact aaacatatct caaaaaatgc aggaatgatg ttaaacacaa agatcgataa
   763141 caaggtagat acactttgag taccacggtc aacatcacgg gtaataccac caatacgacg
   763201 atctagatga aaagacaaat ccaatgtatg taaatgctta aatacactaa ctgcaatcaa
   763261 acgcataata tgataacgaa cacgtacaaa aatcgcatca cgaagctcgt taaataacga
   763321 actagtaagt ctaagcgcac cgtaagcaaa aagtagtcct aacggtaaaa ttaataagac
   763381 attagtctgg tttaagacgt caacgatttc ttttaaaaca actggcactg caacattagc
   763441 aaattttgca acaatcaaaa ataacattgc caaaataaca cgtatacgca tttttaacaa
   763501 ataaggaaat aactttttta aaaccttaat atctctggtt ttaaaatcat aagccttagt
   763561 ttgcttatca gtactacaca cagtgtataa gattattatt gggtaaaggt acgccttttt
   763621 tacaagtaat ttttatcatc tcattggttc taaactaatc tggattctgt aataattctt
   763681 attactaaga tacataacta actaggtacg tataattaca acccaatact ctattcaatc
   763741 acatgtaatg ttgttagggt ttttacctaa taaataaggg tttataaatt tcaattactc
   763801 taactcctta ggtgacatta atgtaagtta aaattaaact tacatttcct ataaaaactg
   763861 ctttaatatc actgttagtc taataattac ctcaaaatat aaccaaacct ttataaaatt
   763921 atttatcaat ctgtacgaac tacttatata ggacttattt ttctgttcat ctatgttctt
   763981 tttcctaggt aaaatattat taattgttta tgcaaaatat tttcacaatt atatctgaaa
   764041 tatgctaaca actttttcaa aaaatgaaac ccaaaacatg acaattgcaa ttaaacttgc
   764101 cttacaagga aggtacggtg taaagtctaa ccctatggta ggttgtgtga ttgttaaaca
   764161 ttccaagatt attgccaaag gatatcacga aagttttggc caagcacacg gagaaattaa
   764221 tgccttacaa caaattaact ataaagctca tggcgctaca ctctacgtca ctctagaacc
   764281 ttgttcacat caaggaaaaa caccgtcttg tgcacaagct attattaatt caggtgttaa
   764341 aaaagttatt atcgctatgc ttgatcctaa tccactagtc aatggtaaag gggttgtcat
   764401 gcttaaatat gcaggtatcg aggttaaaat tggtctttta aaaaatgatg catcaattct
   764461 taatcaagga tttattaagc gtatgcaaac taaccagcct tttatacgtt gtaaagtagc
   764521 tatgagtatt gatggtaaaa cctcaatgag ttcaggtgaa agtaaatgga ttacctcaaa
   764581 agttgcaaga ttagacgtac aaaaactacg tgccaatcac caagcaatta taactggatc
   764641 aggtacaatt attaatgaca accctttaat gacagtacgt cttgatggtg ttaattcaaa
   764701 accactacgt gttgtaattg atagtaagaa tcaaataaca gatacctcgc ttaatatatt
   764761 taacactgat gcaccaacac taatcctaaa cccggataat accaaggtac ttgcctctgg
   764821 caaactagat cttagtaatg ttttaaccca attaggcaat caaggtatta ataatgtttt
   764881 acttgaagca ggtcctaaac tgattggtgc catgattaaa attaatttaa ttgatgagtt
   764941 tattatttat atggcgccta tattaatggg cagtgatgct aattcaatac ttaatctagt
   765001 tattaaagat atgagttata aaataaaact ggatattgtt gatgttagga tggtaggtga
   765061 caacatcaaa ataactgcta ctttaaaatg aacaacctaa ctaataaaca cataatcatt
   765121 ggtgttagtg gctctatttc agcttataaa gcacctgata ttgtacgtcg gttacaagat
   765181 tttgatgcca aggtaaaagt gattcttact aaaggaggag ccaaatttat tactaaatgg
   765241 tcattacaat caatctcaaa aaataaagtc tatcataatt tatgggacga agatgctgaa
   765301 tttggcatga gacatattga acttgctaga tgggcagatg ctattttaat cgctcctgct
   765361 agtgccaata ctattaccaa tatctctata ggtaaagcta atgatttatt aagtagtgtt
   765421 gtcttagcaa gtgatgcatt attgttcatc gcacctgcta tgaacctaaa gatgtatcaa
   765481 tctcacgctc ttcaaaacaa cttatcaata cttattaatc ggcatgcaat tattattaaa
   765541 ccaggatctg gtgagcaagt ttgtggcgat attggtatgg gaaaacttgc agagccatca
   765601 agcattgcaa aacaagtatt tcagcagttt attagcacaa aactaactgg caaaaaagtt
   765661 ctaattactt taggttctac tattgaagct attgacccaa ttagatttat ttctaaccac
   765721 agtagtggaa aaatgggtat ggaattagtc aatacttgta tcgaatcagg agcattagta
   765781 acctgtattt atggcaacat cactaccact ctaaatacaa aatctaacaa catatcaatt
   765841 gttaacgcac aacagatgta tgacaaagtc atggataata ttactaatca agatattttt
   765901 attgcttgtg cagctgtaag tgatttttct gctaaaaata caaaaaatca gaaaattaaa
   765961 aacgatagaa gaaacttaac acttgagctt attccaaaca aagacatatt agcagatgtc
   766021 tgcaaattaa aagaaaaacc tatttgtatg ggatttgccg cagaaacaca aaatatgcta
   766081 aaaaatgcta aaaataagct caaaaataaa ggttgtgatg tcattattct aaatgatgtt
   766141 tcaaatgcta attttggctt caacacggat gaaaacgaag taacttttct aagtaaaaat
   766201 ttaaacaaaa aaattgctaa aagtagcaaa aaaaaagtag caaaaaaaat acttgaaata
   766261 tttattaaag aatacttata aatagtaaaa aagaatactg ttacatcaac acccaataga
   766321 cttactctta atactgtgga taaacgtgtt aatatctcat taaaaagtac ttaaaacact
   766381 tatatattac atctttttgt ggttttgaat aaaaattaat cagttatatt ttttaattaa
   766441 aaatcaataa cttatataaa cctatataaa accattgcct gaaaaaatat ctattaagtt
   766501 atttaaaaac actttagagg aaaacttaac tagtttcacg tgttaaatta agactttctt
   766561 gatatattta acaacaataa attaataata cctttgatta atgtcaacta tttatgttag
   766621 tttatcattt aaatttatca gagtattttt ttatttaaca aaaccttaaa aaatgaaacc
   766681 ttatctaatt ttttaaataa attacaattt tgtaaacagt tattatataa taagtataat
   766741 tatggttatt tttaataacc agatatttat aatctatcct tgaatatccc cttaatcaat
   766801 tcacttatca agtattatta ttataagtag tacaactaat tcttaaaagt gatttaactt
   766861 ataaggaaga tatatattct acactctact tactaatgat aataaacctt gcttacctgg
   766921 tcttgagcta agatattaac agcatcaatt aactgctgat taggtgctac taagtaaact
   766981 ttgtttaaca gcatgctacc tcttaaatta tcaacaatat aagagatttt aactggacaa
   767041 ttacccttat gttcaattag aatcttaata agtttatcaa atattgactg gtgtttagtg
   767101 tttaataata cttcaaaacc cttggcataa cttattttta cttgctcaat attttcaatt
   767161 ttattaacca ctagttgcca ttgatctctg aaatctttat taatcttgcc agaaataacc
   767221 accacttcat cagtcataag ttgattactc actaaagtta aagttttcgt gaataccaca
   767281 gcatttaatg acgcagaacc atcttcaatt gtaattagag caattcgctc tccattctta
   767341 atagagcgat aacgtagatc tgaaattaac gctaatacac gtacatctct attctttcta
   767401 aagacaatat tagaaggtaa tactacatta atgttcttta aatcggctac tgtatactca
   767461 ttagtagggt gattatcaaa ataataaccc agcacacttt tttctaattg taatcttttt
   767521 ttaaacgaaa aacttggtgc taaaagataa cgcgtttcat attcattatg tgaaaataat
   767581 ccgttctgac cactaaaata gtcactttgt ttttgttctg cttgtctaat agctatggga
   767641 taagttttaa ttaaactctc cctattcacg cctaatatat caaaagcacc actataaatt
   767701 aatgcttcaa tggcacgctt attcaaataa cgcttttcaa ttctagaaca aaattcaaat
   767761 aaatccttgt aggtaccatt agtactacgt tcaaatacaa ctgcatcaac caaggctaca
   767821 ccaacacctt taattgcacc aagaccatac aaaactgtat ttttatcaag aatactaaat
   767881 tcgtaattag actcgcacac atttggacca ttaacaatca accccatttg acggatctca
   767941 cttatagtaa atgaaaccct atccgtatca tccatcacac cagataaaac tgcagccata
   768001 aaaggagctg gataatgaga cttaagccaa gcagtatgat aagagacata tgcatatgcc
   768061 accgaatgag acttgttaaa accatagcct gaaaacttat caatcaaatc aaaaatttca
   768121 ttggcttttt tttcattaat acccctttca gcagcacctt taacaaacac actacgttga
   768181 cgattcattt cgctggcttt tttcttaccc atcgcgcgcc taagcaaatc tgcaccacct
   768241 aaagaatatc ctgccatcac ttgtgcagat ttcattactt gttcttgata taaaaataca
   768301 ccattagttg gtttaagaat ttgttctaac atagggtgtg gatacttaac ctgcgcacca
   768361 tgttttacat taatataatc atctaccata cctgcatcta atggacctgg acgatataat
   768421 gctagcattg caacaatatc ttcaaaatta tctgcttgaa gtttctttaa ataactacgc
   768481 atccctttag actctaattg aaaaacaccc gttgtatcac aactttgaag tagtttataa
   768541 actcttttat catctaatgg taaagcatct aaattaatcg gttcatctga taaacccttg
   768601 acgctaatta gtttaatagc cttgtgaata accgttaaat tagataatcc taaaaaatca
   768661 aacttaacca aaccaactgc ttcaacatca tccttgtcaa attgagaaac tacactatta
   768721 ttctcaccat agcctttata cactggacaa aaatcactaa ttttgctagg tgcaatcacc
   768781 acaccacctg catgcgtacc aacgtttcgt actaaaccct ctaattgctt agaaagatca
   768841 attaatgccg ttacgctttc ttctgaatca taacgagctc gtaattcttt agagccccct
   768901 ttctcaggct cactcaaagc tttttcaagt gtcgccctta aatcgttagg aatcatcttt
   768961 gatatttggt cactaaaccc ataaggatgt cccaaaacac gccctacatc acgcaccaca
   769021 cctttagccg ccatcgtacc ataggtaatg atttgtgaaa ccttctcatg accatacctt
   769081 ttagctacat aaccaatcac ttcatcccga cgatcagtac aaaaatcaat gtcaagatct
   769141 ggcattgaaa ctcgctctgg atttaaaaaa cgttcaaata ataattcatg cttaattgga
   769201 tcaacattgg taatacctaa aacataagcc actaaagaac cagcacctga accacgacct
   769261 ggacctactg gtatatcatt ttcttttgac catttaataa aatctgccac aattaaaaaa
   769321 taacctgaaa atcccatttg gatgataata tcaagttcaa attttaaacg ctgttgataa
   769381 atattaacat ctacctttaa gtttttcaag cgttgaacca aaccaccctc tgactcttca
   769441 ctaaaaaatt gttctatagt taagtgttct ggaataggga agtctggcaa ataattcttt
   769501 ttaaataact caaaatgtac attacaacgc ttggcaagct ctaatgtatt ttctaaaatt
   769561 tctggtaaat cagaaaatag cttatacatt tgtttaggtg attttaaaaa ttgctgatta
   769621 gaaaaatgtc gcttacgctg cgtgtcatcc aaaagactac cttgagaaat acaaatccta
   769681 gcctcatgtg catcaaaatc actttcattt aaaaattgta catcattagt tgccacaaca
   769741 gcaataccaa gttcaagtgc caatttaata caaagatgta aatgcttttc atcaaatttc
   769801 cttgaagttc tttgaacacc caaataataa cgatcaacaa aaatagcttg ccaaaactca
   769861 gatttctgct tagccttaac tattttattt gatattaaat atttagctac atcactataa
   769921 ataggagttg caatcatgat caagccttga ttataatcaa ttaactcttg ctgtgttata
   769981 ctgacacgct cgcatgagcg tccttgagta taagacaaag aaatcaattc agaaagatta
   770041 agatagcctt gatgatcttg acataataat aaacctgaat aaagctcacc ttccttatct
   770101 ttaatattaa ttctagcgcc aaatattggc ttgatgttag cagcagtagc tttttgataa
   770161 aatttaactg ctgcaaaaag attagattca tctgttaatg caattgaatc catgccaatt
   770221 tcttgtacct tttcaataaa ttttgaaata cgtactacag agttttcaac tgaaaactca
   770281 ctttgacaat gtagatgtac aaaaccagga ttaaccatta agaataatta aaatgaattt
   770341 aatgaatact tacctatttt acaagtctaa ataaactact ataaagtact taattttatt
   770401 ttaagtagcg ctaataaaca ataaaaatag aagaattctc tagaactcac tagattttct
   770461 tagaacctag gccctgctgt ttttgctaaa atagtttgta atgttgcatt aactgtttgc
   770521 ttatgagctt tatttgccaa gataattgcc gcaacatttt tacctgattt atacaatttc
   770581 ttagcttctt taatcatctt tccagtatcg cgccatgcca tatctgcagc aaggttctct
   770641 ttatagccag tttcagctgc cgcaatagaa gacttaaatg aattagagtt attattccag
   770701 ttatacaaac tacccatata gccagcaaga gctatcaaag taaataatac caaaactatt
   770761 aataatactc ttttcattaa gtatctctct cctattttct atacctatcg gcagtaattt
   770821 tgagaccatt actcattgcc tggtggaaga attccatgtt acgaagtgct tctgtttgag
   770881 gttttaacgg attagcacgt atattcttta aacaactaga gtaacgacgg tgcagtgtac
   770941 ccataccagt ccattttaca cgatacatag gtatgtgagt agtatgacct agtgcaggag
   771001 atagaatatc agcacgagct tttttacctg cgttatatac atggcagtct gcacaagaca
   771061 tattaaactg accacgctta gcataaaaga aaatcttacc tttctcataa gccactttag
   771121 caccaaaaga ctcaactttt acattaatct tttgtccagc cgcttggtct gaaatccaag
   771181 cactaatacg agcaatttta cctttattgt aacttaattt attaccagtt tggttctgat
   771241 aacaattttt aattgcagtt tcaagtgtga ctacttgctg agtcgcttca ttaaagtatg
   771301 gatgttgaat acgggctgct actgggtctt tcaatgaaac acatttgtta agaccaaact
   771361 tcaaatactc cttaccccca tcctccactg cctcttcata aggaggaata ccatctaaaa
   771421 tttcttcaaa ttgttccctt gaatcttgat caatcatata tacaccattg gtatagtctg
   771481 caagttcaac actcggaaaa attgttttaa agtggttaat aaaggctttc tgatcagatt
   771541 taacatcagc taatgccacg ctaaccaaaa aacctaaaca agccattgtg gttattattt
   771601 ttttcattaa tttcacgtta gtaattataa acagttattt agactttaca gtcgcagaac
   771661 ctgtttcacc tttattgctg ttgtacttaa gttcaattat atcgcctttc ttaccaggaa
   771721 ccttaaactt aaaatatgga tttttagaaa ttgaaatacc gatatcagca tctacaattt
   771781 tgttaccatt atgtaatata actatatttt caatataatt cgctggaact attttacctt
   771841 ttttcttacg taaacctgtt tccatagggt gtttaattaa acatttaata ctaatcacac
   771901 ctttttttgc ctttggtttt aatttaatac ttgccattta tatatactcc attttaatat
   771961 aattagttaa ttagccacca caaccgccaa tcgttacctt aacttcttga gttctagaag
   772021 ttattattcc acccgctgtc actaacgcta taactgaaga agttctaccc atcttaacac
   772081 gggtagaaac ataaccatga gcaccagata aattaaatga agccgccaag ggcatagaat
   772141 tatttttaat ataaaaagaa atatctgtta cgtctttaat tttagaagca tccactgtca
   772201 taggcactac ctcaccattt tcagcaattt taggtgcttt aaatttaaat aagccttctt
   772261 tagcacttac aaccgaagta cttactatat ctgatttatc cttaaaactt gcagaattag
   772321 caaaaaccat gcttggtgtt aataaacctg cacttactgc tgtagcaact gcagaacttg
   772381 ctattgcact ttttaaaaat aatcttcttt tcattttgtt ctccttattt tgaataaata
   772441 aaatctgtaa tttgatcaat ttgattttca gttaatattt gatgcttacc aaatggaggc
   772501 ataattgaat atggattttt aattgttgca tcccaaattt gttttcttaa atcagcctta
   772561 tttggaaatc tctccttcat tgcaaataat ggtggtccaa ttgttcctgg taagctacca
   772621 cctggaatca tatgacatgc taaacaattt cccaacttac gaccaaaagt tacttcttca
   772681 ccagtcatct ctttagcacc tgtttgtgct gatatcataa ataatactat caatatcaca
   772741 actgttggga tagaagaaat agcttccttc atgttgttct cctatttata taaatcaaca
   772801 agataattaa accttgataa aaatgaatga tatagcactt aaaaatactt tgcaactctt
   772861 ttattaaagc gttatattat aatattcttt ttttaggaaa agaatttagc acaatactcg
   772921 tactttataa ctttattcaa gaataatttt tcctgttaaa actaactaat aatattttta
   772981 gttagttttc tccacttaaa cttgctgtgc agctttgatc aatgcttgag ctttatgcat
   773041 agtttcatcc cactctgatt gcgctgtaga atcataaaca atacctgctc cagcttggac
   773101 ataaagtatt tgctccttaa tcacggcagt acgaatagca attgccatat ccatacatcc
   773161 atgccaagat aagtagccaa ttgcacctga ataaatattt cgttttaatg gttcaacctc
   773221 attgataatt tccattgctc gcactttagg ggcaccactg agtgtgcctg ctggaaaagt
   773281 tgcttttaaa acatcaatca cactcacgtc atctttaagc tcacattcaa catttgatac
   773341 aatatgcatt acatgcgaat agcgctcaac aaacattcta tcggtcagct taactgtacc
   773401 agtttttgca atacgaccta aatcattacg gcctaaatca atcaacatta aatgttctgc
   773461 aatttctttt tcatcattca ataagtcttg ttctaactct aaatcttgag catgatcttt
   773521 accccgtgag cgagtaccag ccatgggtct aatagttgca cgtctattgt tatctacacg
   773581 agtaagaatc tctggtgaag aaccaataat cataatatca tctaaattaa gataatacat
   773641 ataaggtgac gggttaagac gtctaagttg tctatacaac tcaattggtg atgctttaaa
   773701 tgttgcgcta agtctttgtg aaggaaccac ctgcataaca tcaccagatt taatatattg
   773761 ttgaatagta tcaacagcaa ttttataatt ttgctcacca aaactagacg taaaatttat
   773821 atcactaaag tgatgagatt gataatcttt tttaattaaa ggctggttaa tctgacgctt
   773881 gattttacta agtcttaatt gcgcatcttc aaaatcctgt ttaacaggat taatgtgtgt
   773941 tattaaaaaa gctttattag ctaaattatc aaataccact aaatcattag ataccataag
   774001 cataatatct gcaatattaa actcgtcttt ttgcttggaa aattttaatt ttggttcaat
   774061 atagtgaata atttcataac caaaatagcc aactaaacca ccgttaaact ctggtaagtt
   774121 gttaatcttt ggtacactgt atttctgttg atatttctca atccataata gtgggtctgc
   774181 cactataagt gattcaagca actgtgtatc ttgttcaata cgtacttcat tgccaaatac
   774241 tttaatgaca gtttgtgcac tcaaaccaat gattgaataa cgaccccatt tttctccacc
   774301 ttgtacggat tcaaaaagat aagaataagg tgtatctgcc agttttaaat acaaacctaa
   774361 tgcggtatca gtatctaaaa tcacttcctt aaaaacagga atatgattat aaccttgttt
   774421 aacaaattga ttaaaactag attgattcat ataataaaat ttattgtaat aaaaaaccac
   774481 atcaatttta attaatgcgg ttttcctttt ctaaacaaaa gttaaatatc actcctctta
   774541 cgtttgttcc tctgcttcct ttaattgatc agataatgct tgttgtgcat caactgtttg
   774601 cgtagtaata ctttcaacat attgagcacg acgtacttga tgatgtttaa agcctgtacc
   774661 tgctggaatc aatcgaccca caatcacatt ctctttcaaa ccttggagtg tatctacacg
   774721 tcctgttgtt gaagcttctg tcaaaacacg agttgtttct tgaaacgagg cagcagaaat
   774781 aaacgattca gttgccaaag atgctttagt aatacccatt aacaaccttt gataattaat
   774841 taaatccttt ccctgtgctt ctaattgata gttcatctca atcactcgtc catattcagc
   774901 agtttcacca ttaacaaatg atgaatctcc tgcatcaagg atttcaactt tacgtaacat
   774961 ttgtttaaca atcacctcaa tatgcttgtc agaaatatta acaccttgta aacgatatac
   775021 attttgtact tctctaacaa cataattagc caatgcttca acgcctaata ggcgtaaaat
   775081 atcatgcgga ttagatggac cgtctgaaat tacatcacct ttttcaatcg tctcaccatc
   775141 aaatacatta atttgactcc atttatggat catcatttca gtagctttac cttctgaact
   775201 agtaataatt aaacgatctt tagatttagt agaattgcca aaactaataa caccagttgc
   775261 ctctgcaaga atagaatgat ctttagcctt acgcgcttca aataaatcag caacacgtgg
   775321 cagaccacct gtaatatcac ttgttttaga caaatcttta gggattttag ccaatactcc
   775381 acctgctgca atcacttgat tatcatctag attaatctta acagtcgatg gtagataatg
   775441 tgttgataat acaacttcag aatcattttc ctcaaccatt ttaattaacg gctttaaccc
   775501 ctttgctgct gttgatcttt cagcttcatc aatcatctca aagaacgtta aacctgtcaa
   775561 tggatcagtg tttttattaa ctgtcattcc ctcaacaaaa tctacaaaaa taacgcgacc
   775621 tgcttgctca gaaataatag gatgtgtatg agggtcccaa tcagaaatct tatcttttgc
   775681 tgtaactgca ccaccttctt gtacatgtac aattgcacca taaggaattt tataacgttc
   775741 aacctcttga cccttgttat tacgaatcgt cacttcagaa gaacgagaaa taaccactaa
   775801 atcattattt tcattggtga ttgattttag attttcaaaa tgtgcaatac catcagtatt
   775861 aacattaata ctactgactg cagtagaagc agatgcagca ccgccaatat ggaaagtacg
   775921 catagttaac tgtgtacctg gctcaccaat agattgtgct gcaataacac caatcgcctc
   775981 acctacacca attttatgac cacgtgccat atcattacca tagcatgatg agcacacacc
   776041 ataacgtgta tcgcaagtaa tagaagaacg tactttaatc gattcaatgc ctaattcatt
   776101 gatcttatct gaatcatcca aagatactaa atgacccttt tctaaaaata tctctattga
   776161 atcaggcatt aacacatctt cagctgttac tcgacctaag gttgctgtac ccagggtttg
   776221 tacaatatta ccaccatcaa ttactgcctt cataatcaga ccattgtcag taccacagtc
   776281 gttttcagta ataaccaaat cttgtccaac atctaccaaa cgtctagtca aataaccaga
   776341 atttgctgtt ttgagggctg tatcagccaa gcctttacgt gcaccgtgcg tagaaataaa
   776401 gtattgcata ttgtttaagc cttcacgaaa attggatgta attggtgttt caataattga
   776461 cccatctggc tttgccatta atccacgcat acctgataat tgacgcattt gtgcaggaga
   776521 acctctagca cctgaatcag ccatcatgta aaccgaatta aacgaggcaa gtttctgaat
   776581 cttgccatca acatcggtaa aattttcaaa accaatttca tccatcatgg cttttgccac
   776641 tttttcagaa gtacgtgacc aaatatcaat caccttatta taacgttcgc catcagtcac
   776701 aacacctttg gaaaattgct cttgaatatc tttaacttgg atttctgctt gttcgatcat
   776761 tttagcttta gaatctggaa taatcatatc atttgaacaa aatgaaatac ctgatttagt
   776821 tgaatattga aaacccatat acatcatttg gtcagcaaac ataaccgttt gctttaattc
   776881 ttgagtgcga taacaaacat gaattagatt agaaactact tttttactaa tagcctcatt
   776941 aattaaatta aacgacaaac catttggcaa aattcttgaa aaaatcgcac gacccactgt
   777001 agtatcaaca atacgtttag cactgggttc aaacttaccg ttaactttat gataatcttg
   777061 gatacgtagt ttaacctttg catgcaaagt aacactgtca gactcataag cattaagtgc
   777121 ttcagttgca tttacaaaaa ttagaccctc acctttttga ttaatcatct cacgagtcat
   777181 ataataaaga cctaagataa catcttgcga tggcacaata ataggttcac cactagcaag
   777241 atgtaataca ttattagaag ccaacattaa tgttcttgct tctaattgcg cctcttcaga
   777301 taaaggcacg tgtactgcca tttgatcacc atcaaaatca gcattaaatg caccacacac
   777361 aagtggatgt aactgaatag ctttaccttc aattagtaat ggctcaaatg cttgaatacc
   777421 caaacggtgt aatgttgggg cacgatttag taaaactgga tgttgatgca caactctctc
   777481 taaaatatcc cacacttctg gtgattcgct ttcaaccatt ttctttgcag ctttaatagt
   777541 tgaggctaaa cctttagtct gtaacctatt ataaataaac ggtttaaata attctaatgc
   777601 cattttctta ggtagaccac actgatgtaa cttaaggtaa ggtccacaaa caatcactga
   777661 acggcctgaa tagtcaaccc gtttgcctaa taagttttga cggaaacgcc cttgcttacc
   777721 cttaatcata tctgatatag acttcaaagg acgacgatta ttccccatca cagcacgacc
   777781 acgacgacca ttatcaatta acgagtctac cgcttcttgc aacatacgct tttcattgcg
   777841 aacaataatt tcaggagcat ccagctctaa taaacgtgct aagcgattat tacggttaat
   777901 tacgcgacga tataagtcat taaggtctga agttgcaaaa cgaccaccat ctaatggcac
   777961 caaaggacgt aaatcagatg gaagaattgg taataccttt aataccatcc attcaggttt
   778021 attgccagat tggattaatg aattaactag tttaagacgt ttgttatact ttttaagctt
   778081 agtttggctt tttgtattta aactatcttc acgtaaatta gccgcctcaa cctcaagttt
   778141 catatcagac aaaacatctt gaatggcttc cgcgcccatt tttgcttcaa actcatcatc
   778201 accatattca tctaatgcgt caaaatacat ctcttcagtt aatagttgct tatgaacaag
   778261 aggtgttgag cccggatcag tcaccaaaaa tgcttcaaaa taaagtacac gttcaatatc
   778321 cttaagtgtc atatccatca ataaccccaa acgtgaaggc aaagatttta aataccaaat
   778381 atgcgcgact ggtgctgcta attcaatatg acccattcgt tcacgacgaa ccttagaata
   778441 tgttacttca accccacatt tttcacacac aacattgcga aatttcatac gcttgtactt
   778501 accacacaaa cattcaaagt ctttcattgg tccaaatacc ttagcacaaa ataaaccttc
   778561 tctttcaggc ttaaatgtac gataattaat agtttcaggc tttttaactt cgccatatga
   778621 ccatgaacga atcttctcag gagaagctag tccaactcta attgcatcaa aatcttgttc
   778681 tttttgctct aacttatgaa tttttaataa atctctcatt gaatcctcct aattagtgtt
   778741 gttctaactc aacatcaata cctaacgagc gaatctcttt caccaaaaca ttaaacgatt
   778801 ctggcatgac tgattctgtt aaattcttac catcaacaat actcttgtac atttttgctc
   778861 gtcctgcaac atcatcagat ttaactgtta gcatctcgcg caatgtgtgt gctgcaccat
   778921 aagcttctaa tgcccatact tccatctcac caaacctttg gccgccaaac tgagctttac
   778981 cactaagtgg ttgttgtgtt actaatgagt aaggaccagt agaacgtgca tgcatcttat
   779041 catcaactaa atggtttagt tttaacatat gcatataacc gactgttaca tgacgatcaa
   779101 atggttcacc tgtacgacca tcatataatt gttcttgacc agactctggt aaatcggcta
   779161 atctaagcaa tgatttaata tcttgctctc taataccatc aaacactggt gttgccattg
   779221 gtacaccttc acgaagatta tttgctaatt caataatttc ttcattacta aataatgtta
   779281 aatcttcttt cttaccatga aggttataaa ccttatctaa aaagactcta atctgtttaa
   779341 ccatatcagg gcgtctttca tctaatatag cagcaatttt atagcctaaa cctttagcag
   779401 cataacctaa atgaacctct aacacttgac ctacattcat gcgtgatggc actcccaatg
   779461 gattaagcac aatatctatg gtagaaccat ctgcgagata gggcatgtct tcaaccggag
   779521 atacacgtga aattacacct ttatttccat gacgtccagc catcttatca cctacctgca
   779581 atgttttacg ggttgctacg taaaccttaa ccatcttcat aacacctggt ggtaactctg
   779641 caccttcatt aattttagct ttttcttttt taaaaaattt ctcaaactca actttcttag
   779701 ctttagcttg tttaaccaat actgctactt ctttattcac agttgcattt tcaactttaa
   779761 acttggcaat gtctttattg tcaaattttt tcatcaattt tatgcttaac ctctcaccta
   779821 ttctaatatc accgatagct ttacttagta cattacctaa aagtttcaaa cgaatgcgac
   779881 gaaaaatatc accatcaata atactaaatt catcatcaat atctttttta attctctcta
   779941 aacgttctgc atcaatactt aacgctctaa tatctttttc tacacggtca cgtgtaaaca
   780001 cctgtacatc aataacaaca cctgatttag aagcaccaat acgtaatgat gaatctttaa
   780061 cattattggc cttttcacca aaaatagctc tgagtaattt ttcctcagga gaaagcactg
   780121 tttcactctt aggggttact ttacctacca aaatatcacc acccttaaca cgagcaccta
   780181 cataaacaac acctacttca tctaacttag ataatgctga ctcacttaca tttggaatat
   780241 ctgaagtgat ttcctcagga cctaacttag tatcacgaga ataagctgtt aactcttcaa
   780301 tgtggattgt tgtataacgg tcttcttgaa caaccttttc tgaaattaaa attgaatctt
   780361 caaagttata gccgttccaa ggcataaaag caatcttcat attctgacct aatgccaact
   780421 cacccatatc agtcgatggg ccatctgcta agacatctcc aaaagtaatc ttgtcacctg
   780481 ttctgactaa tggcttttga ttaatacaag tattttgatt ggaacgtgaa tacttagtca
   780541 agttgtaaat atcaacccct agttcattcg ctttagtctt cttagaatct acacgaataa
   780601 ctatacgtga tgcatctact gcttcaacta caccaccatg tttagcagtg acacaaacac
   780661 gagaatcctt cgctacaaca cgttcaatac ctgtaccaac taatggcttt tcagctttta
   780721 acacaggaac agcttgtcgt tgcatgtttg aacccatcaa cgcacgatta gcatcatcat
   780781 gctccaagaa aggaataagt gatgctgcca ctgatgaaat ttgcttagaa tcaatatcaa
   780841 ttagtgttac ttctgatgaa tctactaaaa caaactcatt cttatgacga caagaaataa
   780901 gatcatccat taacttacct ctatcatcca ctaatgcatt tgcttgtgca attgtatgtg
   780961 tgatttcatc aatagctgaa acataaatta cttccttagt caccttacca tttttaacta
   781021 tttgataagg agtttctaaa aaaccataac tgtttgtctt agcataaaca gctaatgtat
   781081 taatcaaacc tatattagga ccttctggtg tttcaattgg acacaaacga ccatagtgcg
   781141 aaggatgaac atcacgtact tcaaaaccag ctcgttcacg agttaatcct ccaggaccta
   781201 aagcagaaat acgacgctta tgagtaactc ccgacaaagg attcacttga tccataaatt
   781261 gagataactg agaggatcca aaaaattccc taactgctgc agatacaggc ttcgaattga
   781321 tcaaatcttg cggagttaat tcatctgttt cagctaaatt caaaccttct cttaccgctt
   781381 tttcaaccct aacaagacca atcctaaatt gattttcaat catttcacca attgctctta
   781441 cacgtctatt ggctaatgta tcaatatcat caacagaatc attaccgtct ttaatattaa
   781501 ttagtaattt aattactctg ataatatcat cattagttaa tacatgttcg cctgtttcgc
   781561 gtgaaatacc taaacggcga ttaagcttca tacgacctac ttttgataga tcatagcgat
   781621 cgtttttaaa aaataaatta ttaaataata aattaactgc atcttcagta gcaggctcgc
   781681 ccggacgcat cacatgatag atagacatac gagcttcaat ctcagtttga gtttcgtcta
   781741 agcgtaatgt atctgaaata taagcacctg tttcagatga attaatgtaa agaatttcta
   781801 ttttcttaac tttattagtg tttaataact ctaatacttc ttcagaagta atagtattag
   781861 ctgatattaa aatctcacca gtatctttat taataatatc agcacagata accttatcaa
   781921 gtaaatactc taacggagca ttgattgatt taatacctgc ttttcccaat aatttaacat
   781981 gcttagcagt aattctacga cctttctcaa ctactacatg ttgattaaca acaatatcaa
   782041 attctgcaat cgtacgttgt aaatgaatcg gcaacatact taaatcacat gatttagctt
   782101 ttaatttaac aggagtcttt tcaaaaaagg tttcaagtat atcctcacta cttaaaccca
   782161 tagcacgtaa caaagtagta actggtaatt ttctacgtct gtcaattcga acatacaaat
   782221 gctcatgatg gtcatattca aaatccaacc atgaaccacg gtaagggata atgcgtgaag
   782281 agaataaaat cttacctgaa gaatgcgttt tacctttatc atgttcaaaa ataacaccag
   782341 gagatctgtg taattgagac acaacaacac gttcagtgcc attaataaca aaagtacctg
   782401 tttcagtcat tagcggtaat tgtcccaaat aaacatcttc ttcaataatt tgcttaactt
   782461 tacgcttttt cttcaaagtt gaaccatttt tatcaaataa aactaaattt aatttaaccc
   782521 gtaatgtaga tgcgaatgtt acaccgcgta acttacattc ttcaacatta aatttaggtt
   782581 cttttaattg ataatcaaca tattcaattt gagcataacc attaaccgca gtaatcggaa
   782641 ataccgattg aagaacgttg tgcaaaccaa tatcttgctt gattttatta tccgcttgaa
   782701 taaaactgtt aaatgaatca atttggattg ctaataaatc tggttcagtc aaaattgatt
   782761 ctctagaacc aaaattattt ctaattcgct ttttttcggt aaatgaataa gccatgaata
   782821 cctcgtattg agttgatcgt gttataaaaa ttttttctta atcaacaaac ttcaatcaat
   782881 attcttcaaa aatatctcat cgagtttgta ctttaattta gtctataaat aagacactaa
   782941 aatcccctta tcgaggattt tggtatctta ttatgcttaa ccaattattt taattctacg
   783001 ctagcgccaa cttctttaag ttgtctttct atatcttcag cttctatctt agatgcactc
   783061 tctttaatta ctaccggtgc agattcaacc atatctttag attccttaag acctagtccg
   783121 gtaatactac gcactgcctt aataacagca acttttttct ctccaaatga ggttaacata
   783181 atatcaaact catctttttc aaccactgta ttatccacat ctgctactac cgcaactggt
   783241 gttactgccg ttgcagatac accaaatttt tcttccattg ctgacactaa ttcaacaaca
   783301 tctattaccg acatatcggc aattgcattt aaaatatctt cattggttaa tttagccatg
   783361 atatttactc cttttattta tttatgattt cttttggtca caaactgctt ccactactcg
   783421 agttactttc attggaacct caattaaggt tctagctagt ttctcaacag gtgctaacat
   783481 taatgccatt atgatgctaa ttgcttgatc tctagttggt aagtctgcaa tacgtttaag
   783541 ctggtttgac tctacaaatt cacctgaaac acccaacccc ttaacaacta aatccttatt
   783601 ttctttaata aagtttttaa atactcgcgc tactgcacct agatcttgtt gtgaaaaacc
   783661 taaaataact ggtccactaa gaactggcaa tacacattca cattttgtac ttactaatgc
   783721 tctttttgct agtgagtttt ttacaacacg taaaaccaca tcagcatcaa tcgcacttga
   783781 acgcaaatta gtcatttgct caactgttaa tccacaatac tcagcaacac cgatagaaac
   783841 tgacactctt gctagcaagt tcacttgtgc aacaactgcc ttttttgcca tcagatttag
   783901 agccatttac ctctcccccc tgaacaattt aaaaaagaaa gtcatctctt gataactttc
   783961 gccacagagt atttatatac cctctacaca ggcagattga aaacatcaat caattaaaca
   784021 aacataccag aagacatgtt tacacctatg gtctctgagg ttatgcaaga taaatcttac
   784081 tacccaaaga attattttaa taaaacttaa atatcaacac ttgccaaatc aacactaaac
   784141 cccggtccca tagtagaaga aatacttaat tttttaaaat aaacgccctt agctgaacta
   784201 ggttttactt ttttaagttc tcctatcaaa acgttaatat tttgcgctaa tgcgcttata
   784261 ttaaatgata ctttaccaac acagccatga ataataccag ccttatcagc acgataacgc
   784321 aattgacctg atttggcatt actaacagcc aaagacacat ctgatgttac tgttcctacc
   784381 ttaggattag gcattaaacc acgaggccct aacaattgac ctagacgacc tacaactccc
   784441 atagcatctg gggaggcaat taccacatca taacttagat caccgccttg catagacttc
   784501 attaaatctt ccataccaac aacatctgca ccagcatctt gtgctttaat cacattatca
   784561 ccttgagtaa acacagcaac acgaactact tttcctgtgc catttggcaa tattactgaa
   784621 ccacgaatat tttggtcata tttcttgaca tcaatgccta aattaatact cacatcaata
   784681 gactcatcaa attttgctat tgcacatatt tttaataaat ttaaagcatc attgattgaa
   784741 taatacttgt tatgctcaac tttagttgaa atatatttct gattctttgt taatttagcc
   784801 atcaaatcaa ccctccacca taatacccat tgatctagct gtaccagcaa taatattaac
   784861 tgctgaatcc atgttgtttg catttaaatc tttcattttc atactagcta cttcttccaa
   784921 ctgagcacga gtaatgctgc caactttgtc caaatgaggt gaaccactac cttttttaat
   784981 atcgattatt ttcaaaatta acaaagctgc tggcggtgtt ttagtaacaa aagaaaagct
   785041 acgatcacta tagacagtaa ttacaactgg cactttcata cctttgttaa tctcctgagt
   785101 cttagaatta aatgctttac aaaattccat aatattaaca ccatgttgac caagtgcagg
   785161 accaactggt ggtgatggat ttgcttcttg tgcagctact tgaagcttaa tataggattc
   785221 aatttttttg gccatttttc ttccttgagg aatttacctc gttctgggta caaacgccaa
   785281 ttaagctccc cttattaaat aacaactttt aaagttgttt gtcgtttaag tcttctctac
   785341 ttgagagaat tctaactcta ccgaagtaga acgtccaaaa attaatactt ctactttcaa
   785401 taaattcttt tcataatcaa ccgcctcaac taaaccatta aattcattaa aaggcccgtc
   785461 aataaccaaa atttcttcac ctggttgata agccacttta ggtttaggct tatcagcacc
   785521 ttcttgtaca cgcataagaa ttttatcaac ttcacgctgt gtgataggag aaggtttacc
   785581 tgatgaaccg ccaataaagc caataacatt attagtattt ttaaccaata accaactggg
   785641 ttcagtaagt tccatgttta ccagcatata acctggaaaa aacttacgtt ctgccatttt
   785701 tttctgtcca tcttttagtt caacaacttg ttcggttggc accaacactt cacctactaa
   785761 atcttcaaga ccttctctaa tagtagattc ttcaattgca atcttaacct tcgattcaaa
   785821 accacttctt gcatgaaata cataccatct tttagacatc ttagtcctct taatttgtta
   785881 acaaatgaac catccacgag aatagtgcat caattatcca caaaaaaata gccacaatca
   785941 caacagcaac cataatcata cctgtggttt taatagtttc atcgcgcgta ggccatacaa
   786001 ctttacgtaa ttcaattttt gtctcaatca aaaacgagct aaaacgaacg ccttgaggtg
   786061 acttaaaaaa tacaaacccg gataacaaaa aaccggttaa caaaaataac actttgtaca
   786121 atgttgtact taaccctaat ggatttaaat aaaaaaaaac aaaagataca accacgatca
   786181 aaatagatac aatcattcct agtaatgatt gttttgcttt aggttctgtt actttagtca
   786241 cattacatcc tttaacatgg caggcaagga ggggctcgaa cccccaacca atggttttgg
   786301 agaccattac tctaccaatt gagccacttg cctataaatc tcaaaaactt gaactattgt
   786361 ccaaaccact ttcatttctt ttttaaatta atttaagttt taactttttg attaatctgt
   786421 cactttagaa actacacctg cacctaccgt acgaccccct tctctaatag caaatcttaa
   786481 accatcttcc atagctattg gtgataatag ctctactctc attttcacat tatcacctgg
   786541 cataaccatc tctataccat caggcaactg acaagcacct gtaacatctg tagttctaaa
   786601 atagaactgt ggacgataat tgttaaaaaa tggtgtatga cgaccacctt catctttact
   786661 taaaatataa atttctgctt caaactttgc gtgtggtttg attgaccctg gcttagataa
   786721 tacttgacca cgttcaactt cctcacgttt tgtaccacga agtaaaacac caacgttatc
   786781 accagcttca cctgaagaaa gtaattttct aaacatctca acaccagtac aagtagtggt
   786841 tttagtatct ttaataccaa caatttctaa ctcgtcacca atattaacaa cacctgcttc
   786901 aatacgacct gttaccacag taccacgacc tgaaattgaa aatacatcct caattggcat
   786961 aatgaaggat ttgtccgtat cacgcttagg agttgggata taagagtcta atgcgtcaac
   787021 tagctttaag atagaaggaa caccaatgtc tgaaatatca ccttctaagg ctttaagtgc
   787081 tgaaccaaaa ataactggag tgtcatcacc tggaaagtca tattcatcca atagctcacg
   787141 aatttccatt tcaactaatt caactaattc ttcatcatca accatatcag ctttattcat
   787201 ataaacaacg atataaggca cgcctacttg tttagataac aaaatatgct cacgggtttg
   787261 agccattgga ccatctgtag cagcaattac aataatagct ccatccattt gggcagcacc
   787321 tgtaatcatg tttttaatat aatcagcatg tcctggacag tcaacatgtg cgtagtgacg
   787381 tatctcactt tcatattcta cgtgagctgt tgaaatggta ataccacgtt ctctttcttc
   787441 aggagcatta tcaatatctg cataatcttt gaattctcca ccacgaactt ctgccatcac
   787501 tttagttatg gcagctgtaa gtgtagtttt accatgatca acatgaccaa tcgtgccaac
   787561 attgacatgt ggtttggttc gttcgaattt ttcttttgac attgtatccc ctttacatgt
   787621 aacaaattaa attttttgga gctcaccagt ggatttgaac caccgacctc ttccttacca
   787681 aggaaatgct ctaccaactg agctaggtga gcacaatcca ctctatttag agcgggtaac
   787741 gagaatcgaa ctcgtctcat tggcttggaa ggccaaggta ataccaatat acaatacccg
   787801 caaaacctac tatgctttta tggtggagag ggaaggattt gaaccttcga aggcagagcc
   787861 gacagattta cagtctattc cctttagcca ctcgggaacc cctccaaaaa ataatcagga
   787921 attatcccat aactatcttt atagtgcaag cgttaattta aggtttttat tgttttttta
   787981 aaagtctatc ttttgctaaa ttacaagcgt gaaacaccac ttgaaacagc aacatcaaat
   788041 actgctttag gcactacctc aatcaatctt ggatcaaaag gtttaggaat aatataatcc
   788101 ttaccaaatg tcatgtactt tgtactataa gcctttaaaa cactatttgg tacttctaat
   788161 tttgctaaat ctttaagtgc ataaactgct gctattttca tctttaaatt aatctcacta
   788221 gcttttgcat ctaatgcacc tctgaaaata aaaggaaaac ctaatacatt attaacttga
   788281 tttggataat cacttcgacc tgttgccatg attaaatcat cacgcaccga attagcatct
   788341 ttaggagaaa tttcaggatc tggattcgac aaagcaaaca caataggcct atctgccatt
   788401 gacttaatca tctgttttga tactaagtta gcaacagcaa caccaataaa tacatccgca
   788461 ccctgcataa catctgttaa ggttttttta tctgtcttcg taccatattg agctttaact
   788521 tgactaacat tctccatatc tttagaaata acacctccac tatcaactaa taaaatatta
   788581 tcctttgaca agcccaattc acataataaa tccaaagtag caattcctgc tgaaccagca
   788641 cctaaacaaa ctaattgaat tgtttcaatg tctttatttt gaatttcaag tgaatttaac
   788701 aatcctgctg caataataat agctgttcca tgttgatcat catgaaaaac aggaatatct
   788761 agcatttcaa ttaaccgctt ttcaatttca aaacaacgag gtgctgaaat atcttcaagg
   788821 ttaataccgc caaatgttgg agcaatgttc ttaactgttt gtacaaaatc atctacatct
   788881 tgagtatcaa tctcaatatc aaatacatca atatctgcaa aatgtttaaa caatactgct
   788941 ttaccttcca taacaggttt agatgccaat ggaccaacat ttccaagtcc taaaactgct
   789001 gaaccatcag aaataacagc aaccaaatta cgtttaatag taaagtcata aaccttattt
   789061 gcatcttgtg caatttcacg aacaggaata gcgacaccag gtgtatatgc taagctaaga
   789121 tcttcacatg ttgttaatga tttatgtgat gaaacgatga tttttcctgg acgattacct
   789181 ttgtgatatt ctagcgctaa tttatgaaat tttgaactca ttacatagtt ttttagatta
   789241 aattaatgtt gtcattatcc aataatcttg ttcacatctt ataatatttt atatataata
   789301 tgtcatagga tataaagata ttaacaatac ctataattta aagatgaaac attagaaaaa
   789361 tccacgccta ttaaatcaat aataatttgc taaaaaatta agaaattttt ctaaactacc
   789421 ttgataagac gtataaatcc atgccataag atggatttta taaaatccct aacattaaca
   789481 tatcattata actatgagca atataatagt tatttttagc aacaagctta agaccaatac
   789541 caagatatct agatcaaaat tcattactta ttgttgggat acagtatttt tacctgctta
   789601 ggtaagctta tttttaacaa gaaaaataag attcctaagc actttcatac tattttatta
   789661 atgaataata aaatatatta gaatcaaaaa tgacaaaatt tcagtttcta gaaagataat
   789721 ctatcctggt ggccaagtta gtacccgtcc gcccaaacaa tgaaggtgaa tatgataaac
   789781 tgtttgtcca ccttgtttat tacaattcat caccacacga taacccttgt cagcaaaacc
   789841 aagatcttga gtaatatcac ttgctattaa tattaacttt cctaataact tctcatcatt
   789901 agtattattt aaagttttaa tatgtgtttt tggaattact aaaaaatggt atggtgctcg
   789961 tggtttgata tcataaaatg caagaacatc ttcatcttca tagatcttat taactgaaat
   790021 atctccatta attattgtac aaaataaaca atcagtcata gccccccaaa taaagattga
   790081 aataagtaaa tttaagcgta ataatggtaa gtttacttca atcagtaatc attaaccttg
   790141 ctgatttaac tatatctgac atacctacct aaaaacacta caacattata aatataccag
   790201 taatggataa ttggaaatct ttacaagagc actattggta tggcaaaaaa aatcaataga
   790261 aaaaaatacg ttgataatga ttgtttcttc catcatcaat ggctggaatt atattccaaa
   790321 taataataaa ctctatataa cttgtttaga ttatgatcca ttgtcaatct gagccataga
   790381 gagttaacca aactttatgg gttcaatacc ccctaaaatc aagcgtcaaa tattaaaatt
   790441 taattgaaat attcttatat atagctatta aattaaaaac cactattctt aaatatatta
   790501 actctaatat atttatatcc gtcatcttta tagagtaaca atacctaata attctacaaa
   790561 gtttaccgat attgacgcaa ataccgccaa ccaaaaatct gtttagcata atgcatcaaa
   790621 cgacaacttg gtaacattaa cccacctttg agtgtccggg atatatacat acctttatta
   790681 tttgaatcaa caatacacat caactcaatc ttaaaggtat gactagtagg cttatcatcc
   790741 aaaacagcca gtacattctt agcagcagcg acagcttgta aatctgccat atgtgcttgc
   790801 ttaggcatcc aatctggtcc tggaaaagaa cctgaatctc ctacaacaaa tatattttca
   790861 gcgcctttaa cttgacaaaa cttatccgct ttaagtaaac cacctttact acgttcaagt
   790921 tcagtactgt caaaccaatg attaccagtc atccctggca taaataaaat caaatctgca
   790981 ataaactcac caccctcagt aatgacctta ttaatctcaa aagactttat tttatgacca
   791041 agatgagttt taatattacg ctttttcatc tcacttagta agcttatcac tgctttttca
   791101 cccaaacgag cgcctggttt ctctgtagga gtaaaaaaag ttaaattaaa tttatcacgt
   791161 cgaccttctc gtcgtaattg tgtatccaaa ccaaacaaaa attcaaacat cggaccacca
   791221 cgtatcgcgc ttaattcatt aggattagca gcaaaaccaa tagcaatatt accactatcc
   791281 ataacttgaa ttctatcacg tatctgttcg acagcactca ctccatcaca tggcgtaata
   791341 gcatgctcaa taccagataa tttcttaata aaccgcccac ctgatgctat aataagcgca
   791401 tcattttcat actcacctac tgaagtaatc acagttctag cacggttttc caagcctatg
   791461 actttaccag aaatatgacg aatattcatt cgtttaaaaa aactattaag cggaataaca
   791521 atatcttttt tattagctat acctgatggt atccaaatca aacttggcat ataaacaaac
   791581 tctgccttag gcgatattaa ggtaatttgt gtgtgtttat cgttttttct aagagttctg
   791641 acagctgtta atcctgcaaa tcctgaccca ataatcgtga ttttattcat tgttactttc
   791701 ttctaataat ttttccaatt cactttgtaa ttcatcgtat aaattttgca attcatacaa
   791761 tatggtttcg ctaaccatct catcaattga gacaatttca ccttgtacag aaccaaacat
   791821 actatcttgt ttatattcga actctatacc cgcctttctt aaatggtttt taaatttatt
   791881 tgataactta gcatcaaaaa atatataatc taacatattc attatttatt aacagttaaa
   791941 ggtattttaa tgcttaacaa agatacactg gacactttat ttcgtcatgc aagaagtcat
   792001 aatggctggt tgaagcaaga tgtgtctaaa acacaatttc atcaaattta tgagttgatg
   792061 aaatttgctc ctactgcaac taacaactgc cctgtacgca ttacttttat taaatcacat
   792121 accgctaaac aacgtttaaa gccacatctt aatgaaggta atattgataa aagcatgaac
   792181 gcaccagcta ttgctattat tagctatgac acagaatttt acaaaaaatt gtcattttta
   792241 tttccccata ctaacgccaa aagttggtat gaaggcaaac ctgaaaaaat aaaattagca
   792301 ggaagtataa acgccacttt acaaggtgct tattttatca tggcaacccg tgctattggg
   792361 ctagattgtg ggccaatagg tggattcaat aaagaaaccc tagacgatga tttttttaca
   792421 gatggtaaaa caaaatctat tttcttatgt ggaattggcc atggtgatca taataaaatt
   792481 ttcccgagat tgccacgttt aagttttgac gaagcatgca aaattattta aacactcttt
   792541 actccataca atagagtaac attttatgtt atttacaaaa aaatttagta aattcttaaa
   792601 aagaataatt atgtatacaa cttataagtc tttataaagt gtatcatcta acgttaattc
   792661 agactcaaca aaaaataaca tagtaaacta atttagttta ctaaatgtta tacatttcta
   792721 aaatataata caaaattata ccttcagatg atctagatgg gcctaatact tttgcagcat
   792781 acagattctt actagaatcc gatttttcta tagcgacatc taaatcttta accacttcca
   792841 cattattagc tggtacacgt tcacgcttaa ttcttggaat tctaatcaca gcaaatactt
   792901 ccttaacaat gttaatactt ggatgtgggt ctattgaata acccttcatg atgtttactc
   792961 tcaattataa ttttttagcg ccgcaatctt gattagcagg tactgcaaca tggattttct
   793021 taggtaaatc caatttaatt ttatttactc tagaaacaaa tatttgttta tctacattta
   793081 aaccaatcat ctcgttgaat tgtttttctt cccagattga actcatcgtt cttccttcgt
   793141 aatcatgagc aggataaact aaggtttcat caggtaaggt aaatattttt tgaatagaat
   793201 catataattt ttccgccgaa ccgccttgaa aatcacatct accacaactt ctaatcaata
   793261 atgtatcgcc tgtaaaaacc tgattaccta ccacgtaaga catacaacca ttcgtatgcc
   793321 ctggagttgt catagcactc aaagtataaa caccaaatga taaaatatca ccatcattaa
   793381 gcaaaatatc cgcacacata atctcgttaa ccgaacctag tacgatttta gcctgagtaa
   793441 agtaccgctt tagaagataa gaactagtaa tgtgatcagc atgcacgtgt gtttcaataa
   793501 tatatttaag attcaggccc aactctctaa taaaggcaat atctctttgc atggtttcat
   793561 ccactgcatc aatgataata gcatccaaag ttttcatatc ggccaaaagg tatgtgtaag
   793621 ttgaactagt tttctcaaat aaaggacgta ataataaact catggtaata cctttttaaa
   793681 ttgtttaata ataacactag taagcaccag acttaatata agttctaaaa aatcaaactc
   793741 tgctactact agtgagactg taaagactac ttactctata gcaggagacc acctggcaaa
   793801 attaaacatc cttgatcctt taaaagctcc aatcgcttaa ttccttaata ttttgtaaaa
   793861 taatagcata tatataactt tttttcaaat tttttccata taattaacgc ttgagatcca
   793921 aaaatacaga gatatatata tatttaagac atctctaata catctttcat tgaataaata
   793981 caacctttat tagagggcac tttagccaac cactctgctg cacgaattgc accaagtgca
   794041 aatgtcattc ttgatgaagc cttatgggta atttccacac gctcaccttg cataaaaaaa
   794101 ctcactgtat gctcacccac cacgtcacca ccacgaattg tagaaaaccc aattatattc
   794161 ctatctctta tctgtttaat accttttcgc ccataaacag cacacgtttt taggtctcta
   794221 cccaatgtat cagcaatcac ttcgcccatc tttaatgcag tgccgctagg tgcgtccgcc
   794281 ttaaaacgat gatgcatttc aacaatttca atatcgctat cttcccctat tacttttgct
   794341 gctatttcca acagttttaa agataaatta acacctacac tcatattagg tgcaaataca
   794401 ataggtatat ttttcgcaag actagttaat tgattgaatt catcatcatt aaagcctgtc
   794461 gtaccaataa ccattttctt gccagcctta gcacaaattg ataggtaacc aagtgtagct
   794521 gctggataag taaaatcaat taacacatca aaattatcta aataattagt taagttatta
   794581 ttttgatcaa tcttaataac taatttaatg ctatttgatt gttcgattgc ttcaataatt
   794641 gcctgaccca ttctaccgtt actacctgat actgctattt ttagcatttg ttattccttt
   794701 aaatgaattc acaatcatat aatgagaatt aatatatact cataagttaa tattggaaat
   794761 attagtattc tatcgaatag gttgttataa tatcttggca taatttcaat taataccaca
   794821 tctaaagaat taaattctac aaactgtctt ctaaaaaacc atgtttctta gtaacagcgt
   794881 ctagttcctg caaggtttta agtaattcat ctattttgtc aatcggcacc atatttggac
   794941 catcactgaa cgcttcatta gggttgggat gggtctccat aaaaaatcct gatacaccta
   795001 ctcctatagc tgctctagca actacgggca ccatctccct ctgccctcct gaggttaatc
   795061 cattaccacc aggctgttgc actgaatggg ttgcatcaaa tactatcgga caacctgttg
   795121 aacgcatagt agataaacca cgcatatcag aaatcaaagt attatagcca aatgaagtac
   795181 cacgttcaca aatagtaatt aacctattac ctgtttcata ggccttattc acaacatttc
   795241 ctatatccca tggtgcttga aattggcctt ttttgatatt cacaggaata ccttgtttac
   795301 acacattttg aataaaattg gtttgacgca ctaaaaaagc aggggtttgc atcatatcta
   795361 caacagatgc tacctcactt agcggggtat cctcatgcac atcggttaat actggcacac
   795421 caacttcatc cttcaccttt tgcaaaatac gcaaaccttc cttaacaccc aaacctctaa
   795481 agctattggt gctggttcga ttagccttat catatgaaga cttataaata aaattaatac
   795541 ctaaatcctc agtaactctt tttaaataag tggcagtttc caaagctaat gcttcggatt
   795601 caataacaca gggacctgca atcaagaaaa atggatgatt aatacctact tcaaaatcta
   795661 acaatttcat gacttatagt ttatacaaaa aatcaacgtt tattatatag ttagactact
   795721 atattaaaca ttatttgata aaaatagtaa aaactaaatt ttcactcata atatacctat
   795781 tacataataa tgtaagaaaa aagatctaat ttaataaatt tttctaattt ttatctaaac
   795841 catacttctg tttcatcgtt taaaatagta atttatgatg aatacacctg atattttaaa
   795901 gaaaattatt gcacgtaaaa aagttgaaat tgcagaatgt aaaaataata ttccagaaaa
   795961 ccagatgctg gatgttgcgt ataaaaacca taatacaaat aacttttacc aagcattgaa
   796021 agataaagta gatacaaagc aaaatgccat tattgcagaa atcaaaaaag catctccttc
   796081 taaaggtgtg ttacgtgaaa atttcaaccc tgttgaaata gccgaaagct acgaaaaatc
   796141 aggtgcaact tgcttatcag ttgtaaccaa taaagacttc ttccaaggga acaatcaaca
   796201 cttaattgat gtatgcgaag caatatcaat acccatctta cacaaagaat ttattataga
   796261 ctcttatcag atttacgaat ctagaacctt aggtgctgat tgtattttac taattgccgc
   796321 ttgcctaaat gatcaacaaa tagaagactt tacaatgcaa gccattaaca ttaatatgga
   796381 tgttttgatt gagatacaca atatagaaga attagaacgt acattgcaat tgcgcctgcc
   796441 aatgattggt gttaataata gaaacttaca cacctttgat gtttccttag aaacaactat
   796501 tgaactgatg aaagaaatca aagaagatac tttgattatt actgaaagcg gtatcctaac
   796561 ttcaaatgat gttgctttta tgaataagca taatatttac agctttttgg ttggcgaagc
   796621 gtttatgcgt caagataatc caggaaaagc actacagaaa atttttggaa agaataaatg
   796681 aatacaacgg ttaaatggat taatgacatg atgatagttg gcgaatcaga tagtggtcac
   796741 gccatagtaa tggatggccc tcaaaactta ggtggaaaga atctaggtat ccgcccgatg
   796801 gaaatgttac tacttggcat aggtggctgc acaactattg atgtgatatc aacactgaaa
   796861 aaaatgtgcc aagaagtaca tacttttcgt gctgaaatct catcagaacg tgctaaagaa
   796921 catccaaaaa tattcactaa aattcacatt cattttgcca ttaaaggagt taatttaaat
   796981 gataaaaaag ttagtaaagc agtcaattta tctactaata aatattgttc tgctttaatt
   797041 atacttggaa aatctgctac tataacacat gattttaaaa ttcataaata atctatgtaa
   797101 ttagctcatc aaaattactg acaacattga tagactatct actttagcca tttaaaatat
   797161 ggctatattt tctttatgga gttaggaatc tactgaatta tccaagactc taaaaataat
   797221 gacagacctt taatcctatt tagacaattt tatatctaca tcttcttaat aatttgtaca
   797281 aacgatgtta ttgagttcac taaagcaata ccatacgggg taaaagatca acttctattt
   797341 cttttatact aagagcacct ccaaaaaaaa ataaaaagca gtagaatgtc aaaaaaagta
   797401 attctaggta ggaaaattct acaagacaaa ctacaatcag tttatatctt ttttacaaag
   797461 taataacatt aagcgtttta aaaatagtga gtagtatttt ttctagtatt taaaaaaata
   797521 acatagaggt gactgaaaga agttctatat aaatatagtt tctaatcata tttcaaatta
   797581 ttatttctta ggcgtataat ctatctcttc ggagagttgg ccgagttggc tgaaggcgcg
   797641 cccctgctaa gggtgtatag ggtttatccc ctatcgaggg ttcgaacccc tcactctccg
   797701 ctatactact tcgtcttttt ttgaaaccta tcttacaaac gtaaaaaata cttatagtac
   797761 gatttaaaag tttaaaaatt aaataaaatt tttaaacttt tttttcacag taaaatactt
   797821 aattactatg attgacatac ccttagtaat tgccaaaaaa acttataact ctcgcttatt
   797881 agttggatca ggaaaatata aagaccttaa tgaaaccaaa ctggcaacgg atatggcaga
   797941 agctgatatc attactgttg ctattcgccg tactaatatt ggacaaaatg tcaatgaacc
   798001 taatctatta gatattattt caccaaacaa atacactatt ctaccaaata ctgcaggctg
   798061 ttacaatgct aaagatgcta ttcgaacttg ccaattagca cgtgaacttt taggtgggca
   798121 taatttgatt aaattagaaa tattaggaga taaaaaaaca ctttatccta atattgttga
   798181 aaccctatct gccgcaaaaa cactagtcga taatgggttt gatgttatgg tttataccag
   798241 tgatgatcca atcgttgcta aagaattaga aaacattggt tgcgttgcaa taatgccact
   798301 cgcctcactt ataggctcag gtcagggtat taccaatcca acacaaataa aactaatcaa
   798361 agaacacgct actgtaccag tattgattga tgctggtatt ggttgtgcca gtgatgccgc
   798421 caaggcaatg gaacttggct gtgatggtgt gctaatgaac tcagccattg ccaatgcaaa
   798481 caacccaatt ttaatggcaa gcgctatgaa aaacgccatt atcgcaggac gagaatcttt
   798541 cctttcaggt agaatgatga agaaatccta cgcctctgct tcatcaccaa tggtggattt
   798601 aatttaacat taaaacctaa acaatacacc tgtatagttt gactaaaata atttattatg
   798661 tatattcatc atatgaatga tatctatcgt tttaattatt ctaaattact aacaaaaatc
   798721 agtgtcattt tattaatcaa tatcaacatc aacaactctg ttttttctct taaatattag
   798781 aaaaaatact actcactatt tttaaaacgc ttaatgttat tactttataa tgacacaatc
   798841 caaattctca tatataaatc agcctctata attattttat taatttaaaa aatataaaac
   798901 acatcataca aacattgtta tgaccgtaac gataattaag atcaaaaaat atacatctcc
   798961 aaataaattt ttattatgct tatgtttaat atatttttat agtccgtatt taattgcttc
   799021 aaccgctata gacatttgtt tttaggaata taagaactaa atattcttat gaattatcta
   799081 aacaatagta agagtttgat tatattgtga ttatattgta ttatcaagtt accttataaa
   799141 atataaaaca aattcatgaa cttttcacaa gaattatcaa atcttaagca aaattatctt
   799201 tatcgcacaa gaaaaatatc taaaaatact caaattagta ttaatggaaa atcattgata
   799261 aatttttgtt caaatgacta tctgtcgctt gccagccatc cacaagttaa agaagcattt
   799321 aaacaaggga ttgataaatt tggtgttggt gctagcgcat cacacttgat tagcggacat
   799381 acagcgacac atcaagcatt agaagaagca ttagctaatt atacaggaca agaaaaagcc
   799441 ttattattct caactggtta tatggctaat ataggagtat tttctgcact taaggataaa
   799501 cttaattggg tattgcaaga taaatttaac catgcttcac tcattgatgc aaatcattta
   799561 attggtttac cacttcaacg atatttacat aacaatctta aatcattaaa gaaaaaaata
   799621 aataagcaaa ctggacaagg actaattgta actgagaacg tatttagcat ggacggtgat
   799681 caggctaaca ttaaaggtat tgaaaaaatt atagaaaaaa ctgatacatt tttgatgcaa
   799741 gatgatgcgc acggatttgg tgtatttaag ccaattattc caaaaaattc aatttacatg
   799801 gcaacactag gtaaggctgc aggtactatg ggggcttttg tagctggtaa tgaggattta
   799861 attgattttt taatccaaaa atcacgccct tatatttata cgacagcaat tataccagct
   799921 ttatgtagtg ccacactaaa aagcttagaa ttaattaaag aaggggaaca aaatactaaa
   799981 ttattggcta atattcatta tttccaaagt ctttctaaag cactaaacct acccattaaa
   800041 gcatctaata gcgctatcca accactcatt ttaggtaata ataaaaaatc aattaatatt
   800101 tcaaaaaagt tattcagtac aggttttcat atcagtgcca ttcgcccacc aactgtacca
   800161 aaaaacacag ctcgtttaag aataacacta agtgctaacc atacacaaaa ccaaattaaa
   800221 caacttctta tccaacttaa atatgttata tagtaacaca gaaggttttg gggttgattt
   800281 agtattgctt catggttggg gatttaactc aaaattgttt aatagtttat tttataatta
   800341 taaaaatcaa taccgcatca cacttattga tttacctgga catggtagaa gtactaatat
   800401 tgatggtgga cttaatgaat ggtgtgatga aattatcaaa attttgccaa gaaatcctat
   800461 tctattagga tggtctttag gtggattact tgccataaat attgccagta aaataactgt
   800521 atcaagcctt attcttattg catcaacgcc aaattttatc caaacaaata attgggaatt
   800581 tggcatagat aaaaataatt ttaagcaatt ttcaaatgct ctacaactaa atttatctaa
   800641 aagtttaaaa cgctttatta gtttgcaaac caaaaataaa tcaaaactta aaacattaaa
   800701 taaaattatt gaacaatact caacaacaac acaagcactt aatcaaggct tggaaatatt
   800761 acttaacaca aacctaaata ataaatttaa aaaactatct ataccaatag aagtagtact
   800821 gggaaaatat gatactttag tgccaattaa aattagccat tggtaccatc aaaataacat
   800881 aaaaacttgt gtcttaaaca ctggacactt gcctttttta catcatgact ttgctctacc
   800941 atcaacgctt gaagttaagt ataatccaag taatacttaa ctttggagaa attgatgagt
   801001 gtactagtgg gtgtcattat ggggtcaaaa tcagattgga taaccatgaa aaatacagta
   801061 aacatactca aagaacttag tattccatac gaggttaaag taatttctgc gcatcgaaca
   801121 ccggatttaa tgttctacta tgcatcaaat gcacttaaac gtggacttaa agtaattatt
   801181 gcaggtgcag gtggtgctgc gcatttacca ggtatggtag ctagcaaaac tattgttcca
   801241 gtattaggcg tacctattca atcatgtgca cttaatggtc aagattcttt attgtccatt
   801301 gcccaaatgc ctgctggtat ccctgttggt acattagcta ttggtaaagc aggtgctaaa
   801361 aatgcaggta ttttagctgc acaaattatt ggcaatgaaa accaaaccat tagaaatata
   801421 gtaactaatt ttagagctaa acaaactcaa gatattttag acaattctaa tcctcaagaa
   801481 taacatatga aagttggtat attaggtgca ggccagttgg gtagaatgct agctatttct
   801541 ggctatccac taaatcacca atttggtttt tctggtgaaa ctcatgacga accatcctct
   801601 ttattagggc atatgtttgc acataaagat aatattaact ctttaataga gttttctgat
   801661 gttattactt atgaaagtga aaatactaaa gttgaaatta ttaaaaaaat taacaaaaaa
   801721 gtccctgttc accctaatga aaaatcatta tttattacac aacatcgtgg tcgagaaaaa
   801781 gctttattta atcagctaaa cattccttgt gcaccctatc aaatggtaaa ttctgaatca
   801841 gatttaaaag cagcaattaa aactattggt ttaccagcaa ttttaaaaac tgtgaccgat
   801901 ggttatgatg gtaagggtca attcctcctc catgaagcta aacagattac taaagcctgg
   801961 aaaagcatga atgatgtaga atcaattcta gaagggttta tcaattttaa acgtgagctt
   802021 tctttaattg ctgtacgtgg tattgataat agccataaat actacccaat agttgaaaat
   802081 aaacatcata aaggtatttt aagattaacc attgcacctg ctcaaaatat taacgaaaaa
   802141 attcaaaaaa cagcacagta ttacatgaaa actttactcg acgaaatgga ttacattggt
   802201 gtgcttacta ttgaattatt tgaaactaaa aatgggttaa tagttaatga aatggcacca
   802261 cgagtacaca attctggaca ttggagtatt gaaggcacta acacttcaca atttcaaaat
   802321 cacatccgtg caatcactgg tatgccactt ggtgacacca caccaacaca tccattttgt
   802381 gcaatgatta atattattag taaactaggg gatattgata ctgtgctaaa aatgccaaat
   802441 acacacctac atctatatga taaatctgaa cgcaaaaatc gaaaactagg tcataccaat
   802501 atcactgcta attctcaagc taagctaaat gagagtattg caaaattaaa aaacttttta
   802561 ccttaataaa atattatcta aaatgcttat ttaaataagt actaatctca ttagattcaa
   802621 acatccactg aacttcatcg ccattagtaa tttttaaaca aggcacttga actttaccag
   802681 tttctcgctg tatttcatct ctaaatttac taccaatagt ttgagcgttg cgcgtaataa
   802741 tgtgtaggtt taatcgttta atcatgcggc gagttttgat acaaaacgga caaccaaaga
   802801 actgatacaa ctcaatatta atagtttctt tatctacttt atgttgttgt tcgctagtac
   802861 gtttaacctt actaactgga actatccaac taataaaagc gataatagca cctaaaccat
   802921 ttctaaatcc ttttagtaaa aatctcatat tcttgcctca tatgcggtta atgtattttt
   802981 taataatgta gcgatagtca ttggtccaac accacctggt actggagcaa tccaaccagc
   803041 aactttcctg acagattcaa aatcaacatc tccaaccaaa caaccattat ccaatcgatt
   803101 aatacctaca tcaatcacaa tagcacccgg tttaatccaa tcgctctgaa tcatcttagg
   803161 aataccaact gcaacaacaa caatatctgc ttgtattaat ttgcaagaga gatttttagt
   803221 tttgctattg cagatagtaa ccgttgcttt agcatttaac aactcacacg ccatcggacg
   803281 accaacaata ttagatgcac caactactac acaattttta cccactaaat ctatttcaat
   803341 agattcaagc atcaacatca ctccttttgg cgtacacggg tgtaagaaag gcttattctg
   803401 catcaattta ccaatatttt cactatgaaa accatctaca tcctttttag gagagatagt
   803461 ttcaattact aaattaacat ctaaatgctt tggtagtggt aattgcacta agataccatc
   803521 aattttatca tcatgattta aacgctcaat ttcaaataat aattcttctt gggaaatatt
   803581 atcaaatcta ttaattattt ctaaataaaa accaacttct ttacaagcat cctctttatt
   803641 acgaatataa acttctgaag catcatcatc accaactaaa ataactgcta aacctggctt
   803701 tctatcaagc gtatcaacct ttaatttaat acttgcttgt aaattttgtg caattttttt
   803761 accattaata acattcataa ttcaacctaa ctcttttctt acttcatcca aatcgcgttg
   803821 tatatcaaca ccatgtccaa cactagcaca agccggtgct acatgaatat cgaacccttc
   803881 gttaagcgct gttaactgtt ctaatttttc aactttctca tatgaagaac tattcatggt
   803941 tagatattgt ttaataaccc ctgctctata agcatataca ccaatatgct tatagcacaa
   804001 ctttaaatca aaatcccttg cctctctaaa aaaaggaata gtagcacgtg aaaaatataa
   804061 agcctttcca attttattaa aaactacttt aacacaatta ggatcaaaat attgcgcctt
   804121 atctgtaatt tgtttacata aagttgctat ttgcataggg ttggttgcta agttattaac
   804181 tacctgatca atcacacttg gatctagcat tggttcatca ccctgcacat taacaataat
   804241 ttcatcatca ttaatatcta acttctccaa cacttgtgca attcttaatg taccagaagt
   804301 gaaatgtccg tcagtcatac aagttattgc accaaaatca ttagcaacta cctcaatacg
   804361 tttatcatcg gttgcaataa tgacacgatt tgcgccacta ttaactgcat tttcataagt
   804421 taattgaatc aaaggctttc catgaacatc tctaagtagt ttagctggca atctacttga
   804481 tgcataccta gcaggtatga taacggaaaa attcattact ttttatcact acctttatct
   804541 aattcacgtg cttcttcgac tagtaagatt ggaataccgt cttcaattgg ataagccaag
   804601 ccactcactt cacaaataag ctcatttccc acttgtttta gtggagcttt acttttagga
   804661 catactaata attttaacaa ggcttcatca atcataattt agcttctagt tctttaaaaa
   804721 aattatcgct caaattagct tcaacttgaa ggtaccacat ttgattattc gcgaattgaa
   804781 tacattttac acaatcttta gcagtcataa gaattggata attatcttca aatactaaat
   804841 cactttgttg atacacataa tggtcagcaa atatgtgtgg ttttaaatta atacccaatc
   804901 taattaatgt atcaaaaaaa cgttgtggat aaccaatacc agcaacacca tgacaatatt
   804961 caccattgaa ataatccaat ggtttttcct cgcctgtttt aacattaaca aatactttta
   805021 atattagttt aatgttaaat tcacctgcac gaaaaccagc attatttatc acaaaatcaa
   805081 cacttttaag tctgtcaatt gattccctta aaggccctga tggcaagaaa aattcattac
   805141 caaaacgtcg agtaccatca ataacagcta tttctatatt tctatccatt ctataatgtt
   805201 gtaaaccatc atcactgatg attaaattaa cttgacattg atttattaaa tcctcaaccg
   805261 cctgtgccct attcctatta accatcaccg gcaaatctgc ttgcaaagcg ataagcaacg
   805321 gttcgtcacc tgataaataa acgttagtat ttttactcac taacaaacta cctttatgat
   805381 gcataccacc gtagccacgt aataccacgc caacttgctt gccttgttgt ttaaaatact
   805441 gtgccaataa aatcacaatt ggtgttttac cagtaccacc aactgtaata tttcccacca
   805501 caattacagg acatttaaat tttttaacct taaaaaaatt aacttgataa agccattttc
   805561 taagtactga tgctaaataa aaaatacctg atattggcag taataaataa ttaataatac
   805621 ctcgagtatt taaatccatt attatctagt acttattttc aattttatat tttttcttat
   805681 caaatttcaa catcactacg gataactaat aatattaaaa ttaaggtaaa cgtaataagt
   805741 aaattaaact tattattgac cattaaatat ttcatatcaa tcactaagaa acgagtagta
   805801 actataatgg caataactat cattatatta actttagaat aaatatccat cattgcacct
   805861 ggttttaagt aaataaaagt aaaatatttt taaataatac aaatactcat gtgtagcaaa
   805921 ataaacaatt attaccccac cacaaataat cctaaaatat atatcgccct gttgattagt
   805981 ttgatatttt attgttagat taaccatata tacattttta tttaactatt tatagcagtg
   806041 ctaattatga caaaatatta tcctaatgag tatcgaattt ataatttcta atcaatactt
   806101 acgctccaat caaaaaaagg gttttatttc ctttattcct ggagtttcta tagtgggttt
   806161 aattctatct gtcgtcacct tgattacagt gttatctgtt atgaatggat ttcacaaaga
   806221 acttagagac agagtactaa ataccatttc tcattcatat attactcaat acaataattt
   806281 agttgataac tggcaaaatt tacaaactaa aattaacaaa catcctaatg ttgttagtac
   806341 ctcaccttat attgaaaaat atgctttgct aagtacacac aatggtactc aaggagttaa
   806401 tgtacgaggt attagaccta acttggaaaa aaaaacttct attctattag acaaaattaa
   806461 gtctggtaat gccaacttgc ttaaatcaga tattttaatt ggtacaggat tggcaacaca
   806521 actaggttta attattggag ataaaattac actacttaca cctaaattat cttctaatat
   806581 tataggcatt cagccaaggt ttaaacgctt tactattagt ggaatctttg atgctggtat
   806641 tagcgaatat gataataact tagcatttat tagcttagaa caagcacaaa agttgtatat
   806701 tatgaaggat aaagtctctg gtattcgact taaggttgat gatttattta atgctaagaa
   806761 gatcactaat gaaattatta ctaacttgtt agacggtcga tattatggta ttgactggac
   806821 tgaacaaaaa gccaacttta ttaaagcgct gaatcttgaa aaacagatga ttagtattat
   806881 aatgtcgctc attattgcag ttgctgcttt taatattgtt tctatgatag taatggtggt
   806941 aaatgataga aaagccgata ttgctatttt aagaacactt ggcatgacac ctaatcgtat
   807001 tgtaaaaata ttcctttatc aaggattaat aattggtcta attggtatta ccattggtag
   807061 tatcttaggt gtattactct ctcttaatat tgaaatgatt gttagtggta ttgagtctat
   807121 tttgggcttt cagttctttc caaaagattt attctatatc agtcgatttc cttctgaaat
   807181 acatataata gatatcgtta aagttatctt tggcggtttt attttaataa caattgcctc
   807241 tatttatcca gccaaactag caggaaaaat agatattgcc aaagtgttaa atcatgaata
   807301 atattattga atgcaacaat attagctata cttactttaa tggcaaacaa aaaataccaa
   807361 tacttaataa cctcaactta aacgttaaac aaggtgaatc aattgcaatt ttaggacaat
   807421 caggctgtgg taaatctact ttgcttaatc tattgggtgg tattgataaa cccactcaag
   807481 gaaagatact tatcaatgga attaatctaa atacattaaa cgaaaacgat actacgttat
   807541 tacgcggtaa atatttaggg tttgtatacc aatttcatca tctgctaaat gattttagta
   807601 tgcttgataa tgttgccatg cctgagcgaa tacaaggagt gaatcagaaa tctgctcaag
   807661 ccaatgctaa aaaattactc tcaaaaatag ggcttgaaca ccgccttaat cacttaccaa
   807721 gtgaactctc tggtggtgaa cgacaacgag ttgctattgc aagagcctta attacaaatc
   807781 ccagttgtat tttagcagat gagcctactg gaaatttaga tgctaaaaat actaacgaaa
   807841 tactcaacct aatgttggaa ctcaatcatg atcagaactg tgcactcatt attgtaactc
   807901 acgatgaaaa aatcgctata aaaatggata aatctctcat tttaaatcat ggaatattaa
   807961 caacgtagct aacctaaata tcaaactatt tatgtttcgt gctgtctgtc agtgctatag
   808021 atgaataaat ctgtttattt cttacattac ttatcaattg atgaatattt ttcaacaatt
   808081 attgtgttaa taataaaaca tacaaaaaac actagaaata ccagaagtta aaaaaataaa
   808141 acaagaaata caatattgaa aagaatgatt acactaaacc ccaaaaagaa caaaatctat
   808201 aagtaagtaa acatacttat agataataaa aacatggctt taattatctt ttcaaatgct
   808261 aatataaatc ttaatcaaga attggcgcat aatctgtata aacttattgc taaggtattg
   808321 tctttcattg taaaaaaata tttttataaa atataaaatg tctaaatatt gcagaattat
   808381 caaccaaaat taatacaaac ttgatttttt actccctgta cttatcttag ttaggatatt
   808441 tttattatta acataacaca acctaggtgc ataaccttca agctcttctt cagaatacaa
   808501 agcatatgca gcaataatta atacatcgcc tacattcact ttacgagcag cagcaccatt
   808561 aactgaaata ataccagaat tatccttacc aagaattgta taagttgtaa aacgattacc
   808621 attattaata ttatatattt gaatttgttc aaatgcacca atacctgccg catctaacaa
   808681 cacaccatca atctcacaag aaccttcata gttcagttca actgcagttg ttgttacctt
   808741 gtgtaattta gcactcaaaa aaattctttt cataaaaatt aactaaccta aaaactgaat
   808801 cataatacca gctgcaattg ctgaaccaat cacaccagca acattaggac ccattgcatg
   808861 cattaataaa aaattatgcg ggttagcttc taaacctact ttattagaaa cacgagctgc
   808921 cataggtact gcagaaacac cagcagaacc aattaaaggg ttaattttat ttttactaaa
   808981 tatattcata cattttgcca ttaacacccc gcaagccgta ccaatagcaa aggctaccat
   809041 acctaaaagc aaaataccta aagtatctaa ttgtaaaaac ttttctgcca ttaattttga
   809101 acctaccgcc aaacctaaaa aaatagtaac aatattaatt aaagcatttt gcattgtatc
   809161 actcaaacga ttaaccactc cagattcttt cattaaattg ccaaaagcaa acatacccag
   809221 tagtggtgct gcatcaggca acaataaagc cactaacatt aacaacataa taggaaaaat
   809281 aatcttttca tattttgata ctttacgcaa ttgaaccatt tcaatttggc gttccttctt
   809341 agttgttaaa gcacgcataa ttggtggttg aataagtggc actaaagcca tataagaata
   809401 agaagcaact gcaattgcac ccaataaatc aggtgcaagt tttgacgcaa cgtaaatact
   809461 agttggtcca tcagcaccac caataatacc aatagcagca gcatcagtca agctaaagtc
   809521 aaaaattcct actactgtta aaccaatagc gcctaacaag gtagcaaaaa taccaaattg
   809581 tgctgctgcg ccaagtagta atgttttagg gttggccaat agcggaccaa agtcagtcaa
   809641 tgcgcccacg cccataaaaa taataagtgg aaatgcacca gactcaatac caatcacata
   809701 gaatatatgc aaaataccac taccttcagc aatacctgcg cctggaatat tagctaaaat
   809761 tgaaccaaaa ccaataggta ataacagcaa tggttcaaaa tttttaacaa ttgccaaata
   809821 taaaagtaaa ataccaacca atagcattaa accttgtccc caagacattt gatgaagacc
   809881 tgtgttaatc caaagtgtgt ttaattgttc catattaaaa tctaaaatta tacgagtatt
   809941 aataaagttt ggcctacgtc aactgtatca ccttccttaa tctcaatatc agtcacaaca
   810001 ccacttctag cagccttaat ttcagtttcc attttcattg cttcaagaat aaccaaaaca
   810061 tccccttgtg caattttttg attcacttca actattactt tccaaatagt cccggatagt
   810121 ggagcaccaa taacctcgcc ttttgttgtt ggtgctatac taagtatttc tttttctact
   810181 ggagttgata attttgtttg atcataagaa gctttcattg acgtaatatc accccccgct
   810241 gaaacatcaa cagtataaga attaccttta aacgaaacgg tgtaagtttc ttcctttttg
   810301 tcagatcttt gacaactctc aactatctgt gacactggct caaagaaatc aggattatct
   810361 ctattttgta agaataaaat acctacttgt gggaataatg cataagtcaa caaatcatca
   810421 atctttcctt tagccaaaat aattcctttc ttagcaacaa ttctatcaaa ttctttttca
   810481 agaatttgca tctctggtgc aatattatca gcaggcctac aagtaattgg ctcaccacca
   810541 tccaaaacct taaattgtag agcttgatca acaggtgcag gtgttgcgcc atattcacct
   810601 ttaagtacac cagcagattc tttagtaatt gttttatagc gttcaccagt aagtacatta
   810661 agaacagatt gtgttcctac aatttgtgaa gttggcgtta ccagtggtat ataacctaaa
   810721 tccttacgta cacatgcaat ctcaactaat acttcatcca ttttatcgag tgcgccttgc
   810781 tcacgtaact ggctttccat attggttaac ataccacctg gcacttgaga taataaaatt
   810841 cttgaatcta cccctttaag cgagccttca aaatgtgtat atttacaacg cactgatcta
   810901 aaataactat caatttcttc tagttttttc aaatctagtc ctgtctttct tggactattt
   810961 tctaaaatag aaaccacaga attagtcgca ctatgaccat aagtcatact catagaacca
   811021 atagccgtat caacacgatc aataccagct tcaacagcct taacaatggt agcagtagat
   811081 aatccagttg ttgcatgagc atgtaattga ataggaatat caacaaccat ttttaatgct
   811141 ttaatcaagt cataagctac atatggttgc aataaacctg ccatatcttt aatacaaagt
   811201 gagtgtgctc ccatatcttc aatttctcta gccatgtcca gccatgtttg aatattatgt
   811261 acaggactaa ttgtatagga taacgtacct tgcgcatgtt gaccaatctt aaccgcttga
   811321 tcagttgctg ttttaagatt acgaatatca ttcattgcat caaaaatacg gaaaatactc
   811381 acaccatttt ttgcgctttg atctacaaat ttacgcacaa cgtcgtcact ataatgacga
   811441 taacctaata aattttggcc tctaagcaac atttgttgag gcgtgttagg cattactttt
   811501 ttaatctcac gaattctatc ccagggatct tctcctaaat aacgaataca cgaatcaaaa
   811561 gttgcaccac cccaagattc tattgaccaa taaccgattt tatctaattt atctgcaatt
   811621 ggcaacatat catcaatacg catacgtgtt gcaaataaag actgatgccc atctctaaaa
   811681 acaagctctg taatttccac ctttttacct tgtaaactat cagacctttt agttagtttt
   811741 ttaaaaaaat ctagcatgat ctctatgctc ccctatgcat ttttattgct tgttcgatga
   811801 taaatttagt ttcttcatcc atctcattct taaactcaga attatgataa tcttgcttat
   811861 catgagtttt actttgcaat ttttggataa ccatagacat tagcttagta ataccaacta
   811921 acaaagttaa aaataaaaat acaaacccca taccaaacaa agttaaatta agcgcttgag
   811981 ttataaaatc tatttgtttc atattatgat tttttattaa tttggtaccg atggacggaa
   812041 tcgaaccgtc acccccgaag gaactggatt ttgaatccag cgcgtctacc aattccacca
   812101 catcggcaat attttttatt tatgtctaaa agtaattctt cctttagtta agtcataagg
   812161 cgtcatctca acggttactt tatcacccgg aaggattcga atataatgct tgcgaatttt
   812221 gccagaaata tgtgccagaa tacaatgacc attttctaac tcaaccataa aagttgtatt
   812281 aggtaacttc tctttaacaa aaccttctaa ctcgatgtaa tcactttttg acataaaatc
   812341 gctataaatt tccaactaaa accaagttat tttacccgat tatgagagga tagttaaaaa
   812401 atcataagct agatatctag cttttataga aattgaaaac tctttaatct taactaaatc
   812461 agttataata atataatttt attataagca tgttgtatta atgaaaatca gttttgagtt
   812521 ttttccaccc aaaacagaac agggaaaaga aaaactaatc caagttagac aaagtttaag
   812581 tgtagtatct cctaagtact tttcaaccac ttctggtgcg gggggtacaa cacaagatac
   812641 aaccttagaa acagtattag atattcagaa aaataacaat attccagcta cgccacattt
   812701 atcttgtatt ggtttaaaaa aatctaatat tattgaatta ttagacaaat acaaagctat
   812761 aaatatcaat catattattg cactaagggg agatattcct tcaagtataa gaaatatggg
   812821 tgattttaat tatgctaatg aattagttga atttattcga tctaaatata atgacaactt
   812881 taacattgaa gtagcagctt accctgaaat gcacccacaa gcaaaaaata taaaaagtga
   812941 tttaacacac tttgttaaca aagttaaagc aggtgcaaat ggtgcaatta cacaatattt
   813001 ctataatgct gatgcctatt ttagattcca agatgacgtg caaaaactag ggataaacat
   813061 tccaatcaca ccaggaatta tgcccattac caattatact aaattgctta atttctctaa
   813121 tatgtgtggt gcacaaattc caaaatggat tttagaacga cttaaatttt atgaaaatga
   813181 tctagaatca cttaatgatt ttggctttga tgttgttgct aatttatgcc aaacactcaa
   813241 gaaccaaggt gtaaatagct tccattttta ctcaatgaat ctcgttgaac catctcttaa
   813301 gctagcaaaa aacataatat aaataatgta ttctcaattt aaattagatt gtatcttaat
   813361 ccaatattga agtttatgca aagactcttt atcttgagta tgacaacatt tctcaaatat
   813421 atttaaacga ctatacagtt cttcaaacac cattacataa tgttcattcc ttagctcttc
   813481 tttatatagt ttagatttaa gtgcagtaac aatattgatt aatttttctt cattttcttg
   813541 tttagtaaga tcagctacac cagctttaaa catagcatca gattttatct gttgcatttt
   813601 ttgtatgtat ttatcttgtt ctgaatataa acttatctta gggtaagcta atctaatgct
   813661 atccgttgtt acatagcctt cgtgagtttg taacttgcct aaattaattt gtgtttgaat
   813721 atgagcacga ctcacgccaa gtttacgtgc tgcttgtgaa acgcttaatt taatcacact
   813781 tgctctccaa agaaccatta aagatagttg ataaactaac tatattttac tggtttgtca
   813841 agtgtattaa gattcattaa tactgaaata ataccattat tactagtatt tggagtaact
   813901 aatactttat caaactcaat tgaattaaca taaattttga tcctttcact caaaacgact
   813961 aataaatagt tttttaattt atcaatatga ttaatttgat taactatttt tattagagat
   814021 ttcatattat ctatacttgt gatactaata acaccctctc tacttaacaa aaatttatca
   814081 agagattgac aatgtaagtg actaatatca cagcaaacac gttcatacac ctcaacatat
   814141 tcaacttgat tgccttgctt aatcaaacct tgctttaagg tctctctacc acctttaccc
   814201 ctaaaaatta aaattgtttt atcatttaac tgggttacac tatcaagttc taacagtgct
   814261 tcgctagaag ctttattttt aggaaaatca ttaataatga tattattttc actcaacttt
   814321 ttagcagtag cactacccac tgccaaaacc tgctgataac taatattttt cagaatcttt
   814381 aatccatatt caacagcatt agcactaata aaaataatca catcataatg atttttttct
   814441 agtttaatat cgatagggtg aagctttaaa gttggaaaaa aaagtggatt atttccgctt
   814501 ttaaccacca tatcttgtag tttttctact tgtaaagctg gtctagtcaa cattacattc
   814561 actgactaaa atcctaatat ttcagcaata attcgtattt tattcaatgt ttcactttcc
   814621 gcatacttac aaataagtat aattttagta ttaactaacg atacatcttg taaaaaacgt
   814681 cgaatttgtt tttcatccca aatgttagaa gtataaagaa taggaaattg agtaaaataa
   814741 aaatatttat ttgttattag cttagtattt agatcaaact taagtttgtt atcagactga
   814801 aaacataatt tataaccact taatattttc attacttcat tacttggttg ttcatccagt
   814861 tcacaaaata aattaaatcg agatcgatat tgatggattg gtttaagtaa taatttaagc
   814921 atagatatct ctaataactg tgtctgttca atgtatacaa ccaattcaaa tacctcatct
   814981 gactctttca attctataaa tatctgttca agatcctcct tagtatcaat ttttaaagat
   815041 aatgctttga ataaggttga ataataatca aaccgccatt cattaggtaa atcatcagga
   815101 taaaaatcgt caagcaaatc taaatcacta cgaccaatta agaattctgt tttattcatt
   815161 tggttttata cgtctttata ataaaataaa agttttatac aaagatctat ttattaacta
   815221 tgccagatat tctactacca attattgctt tgttatcagg atttacactt ttaatttgga
   815281 gtgcagataa atttactgaa aatggggtaa aaattgctaa tatttttaga atatcgccct
   815341 ttattattgg gataatcata ttagggtttg gcactagtat acctgaaata ttagtatcga
   815401 cacttgccgc tataaaaggt aatacagggc ttagtattgg caatgcaatt ggttctaata
   815461 tttctaatat ttccctaata ttaggtatta gcgcaattat ttccccaatt aacgtgcaat
   815521 ggaagatctt aaagaaagaa tggttatttt taatgattac tacactttgt gcaggacttt
   815581 tgttatggga ttatcgcctt gatttcaaag atggtttgat tttattatct ttattggttt
   815641 tattttttgc ttatatcttt aaacaagcaa aaaataaaac acatcataat tttaatgaag
   815701 ttaaacataa taccaataag gatcaaatta aaaaaactaa gataattcta attataagct
   815761 taacgatttt ggtctctagc gcagaacttg tagcttgggg tggtatagaa gtagctaaaa
   815821 tatttggtat ttcagatctt attattgggc tcagcattat agctctagga actagcttac
   815881 cagaactggc agtatcaatc tcaagcgttt tgaaaaaaca atatacaatg gtggttggca
   815941 atgtaatcgg ctctaacata tttaacatta ttgctgtatt agctataccg ggattaatcc
   816001 acccatcaga tgtaccaatt gaagttataa atagagacta tccagtcatg ttattattga
   816061 ctatattatt gtttgttgtt tcttacaagt ttaacaaaaa acatattatt aatcgcttgg
   816121 aagggttttt tcttattggg atatttagtc tttatatgtg gcaattatta tgaaattaac
   816181 tcttcacaat gagtctgata cttatgaatt tgcacatcaa ttagctcagt gcactcaatt
   816241 agttaatagt tgcattgtta tttatttaga aggtgattta ggagttggga aaactacatt
   816301 tgctaggggt tttatccagt tctatggatt tgatcaagtt aaaagtccta cctattctct
   816361 tgtagaaagc tatatcaatg ataaagtcaa tattcaccac tttgattgtt atcgattagg
   816421 cgatgcacaa gaattagaat atattggtat tagagaatat ttagcacctg gtcatattca
   816481 gttgattgaa tgggcagaat taggtaaagg catgattgcg ccaacagata tgataattag
   816541 aataactgat catttggata agcatgaact acaaataaca actcatacac aagttggtaa
   816601 tcaactactt gcatgtatca actgataaaa actttttcca gtaaaatata tttatctttg
   816661 ttacaaacaa tagaaccata ttgtttatta aatagtacct gaataaacta aaactataat
   816721 tgatatgaaa ctaagtgtta aattttcaat taatacacaa aataaatcaa tcatacttca
   816781 ccatttattt caatttatac taattcaaga actatagatg ttctagttta gatcttatca
   816841 aagcatgata attcaactaa atttactaat tgatattaaa aaggaattaa ttaaaaatgg
   816901 ccaacatttg aataaaattt tatataatta ctctagaaaa aataaggata tccatagaca
   816961 gaaattagaa ttttaagata cgctaaataa aactaactct ttacataaaa accacaaaaa
   817021 agaagattct attattttaa taatgccata aacttcctct gtgttagcta gaactacatt
   817081 tatttttaat ctttaaaata aataataact taaaatccaa aagaacaaga taatattgct
   817141 aacacaattt attattatgg gtattttaaa ttattacaag taaaacttaa acaagttatt
   817201 ttttatttaa tttatcaggc gcacattcct tttctggtgg ctcataattt ggatcgtttg
   817261 ggttcataaa cacaaaatga taatcgctgt ttttatctat ctgatcaaaa tctaccacca
   817321 taccttcaag taatattttt tgttcataag caaaaatata ctcaatacca ttagattcaa
   817381 ggtgaatatc actatcatta cgatcatcaa aacccataaa atattggaac ccatcattag
   817441 ttttatcgac agaaaaacga atcaataatc ctttgttttc tggattatga gttgataaaa
   817501 taatctcatc cgacgctttt tttgtaatta taatcataat tcctgttttt taaccttatt
   817561 tataaaattc acaaattgta taacccatgc attattcgct acattatgca aatgtgtgta
   817621 cgaagccaaa agattatact tcataatacc atcaaactta ttattcacac ctacaccgcg
   817681 caaaacatta aaagcatagc gtgtattaga actaatattt ttaagctttg agtagtgaaa
   817741 ttcatgtgcg taaatatgct tagatactcc agcccaacaa tgcttatcgg ttggttctaa
   817801 ctcaacataa cctctaccaa caggcttaga catcatataa gtatctgcat caattacacc
   817861 catcattgaa taggtttttt tattatgagt aatgctattg gttaaataca ttaaaccacc
   817921 acattctaca tacgttggta agtcttgttc tattttagtt ttaatatcta ctaataagga
   817981 ttgattagca tttaacgctt caagttgcat ttctggaaaa ccaccaccga taaacaatcc
   818041 atcacatatt ggcaaattat tatctttaag tgtatcaaaa tattttattt taacgcctaa
   818101 tgattcaaat ttatccaaat catcttgata ataaaaatta aacacagcat ctttagcaat
   818161 agctataatg attttttcct taattgtatt gatatttgta tatgtgttaa taattttctt
   818221 attggattta atacaattaa aatctactaa tgtattaaga tcaacttgat cagtaataat
   818281 attggtaact tttttgataa aagtttgcga ttgtggtgtt tcgttaacag gtattaagcc
   818341 tagatgacgt tcatcaatta ttaatgcttt agaacgacgt atacagccca acacagggat
   818401 atcagtatag taattaatag cttgtatcaa ttttgattca tgacgctcac tagctacttt
   818461 atttaagata acaccagcaa tatttatctc tttatcaaac acttgataac cactaagcag
   818521 tggtgcaacg ccacgggtaa tacctgtact gtcaatcact aatatcacag gagtcattaa
   818581 taatttagca agatcggcgt tagcatcacc accagcaaca ctcataccat caaacaaacc
   818641 tttatttcct tcaataatat caatatcact atttaaactt tgattttgat acaactggat
   818701 aatttcatta tcagtcatgt tataaaaatc tagattataa caaggatttc cactggcttt
   818761 agaaagccaa ataggatcaa tataatcagg acctttttta aaagtctgaa catttaaaga
   818821 tttttgttta aatgcagcac ataatcctaa actaataaca gtttttcctg atgatttatg
   818881 agcagcagat agataaaacg ataagggcat taatatctac ttaattttaa tataaaatca
   818941 tcttttataa tataaatcag ccaaatcatc ttccaaactc tccggtaaga atgctaaaaa
   819001 tttaactaaa aatgtaacta taatgattgc taaagcaata ccaccaatac caagaaatac
   819061 ttctggtaat gaaactaaat attgagcaat atcgccataa ccctccaaaa cctccttacc
   819121 tggaaataac tccattggat aagcctgacc cccaatgata ataacatata actgaataaa
   819181 ccccccaata ataattaaca cagaagacaa acctaacatt gaacgatctc ctttagtaat
   819241 aggatgataa atcaatacca tgggtacaat accacccaaa ataatttgac cataccaaaa
   819301 taattttgta taaataccac catcgaaaag aataaagttc tcaataccag tattttctgc
   819361 taagtacaaa ttacccaaat gatataccgc tacaaaatac ataactgctg caacaaacac
   819421 acccaaaaga tttctcaaac gatttactat aatatttcct aaaggtctat tagtccactt
   819481 atagctcgcc attaagatca atatgaaaga tgccaaccca aatgaaaaag acataatgat
   819541 aaacatagga gccataataa cagcatcata agcttgtcta gcaactaaaa acccaaaaat
   819601 agagcctgtt cctgtagtta aaattaaacg ccaactaaaa gcaactaaac ccactttatg
   819661 actaaattta ttcatgcgac gctcaaacat catccataaa taaatagcaa ctactacaaa
   819721 gaagccatta tataaaataa tattccaagc aaaaattgat ttaaaattat attcagtcat
   819781 tgcaacaatc aaacgatcta tacgccctaa atcaagaact aataccatta accccccggc
   819841 taataatgat aacgcaacta aaccagacaa acgtgataat ggtttatata acttcttatt
   819901 aaacacagaa gaaattgaag ccacgtttaa tgcaccactc gctgctacta tcaaaaacaa
   819961 agcaaaaaca tgtggcatac cccatacaat acgattattc ataccagtca caaaatgacc
   820021 atgatgctcc acatagtaca cactacccag tgcagccaaa attaaaatcc ccagtcctgt
   820081 aattaaaata taaaatccta ggctttttcc ttcaatttgc tcaaaacgaa tattactcat
   820141 aaaattccaa aattaaattc attatttaaa taccactata gcgtacgcca gtatttagat
   820201 taagatctgc cctgatttgt gaagattgaa ctattttcaa ggtttggttt atttggcttg
   820261 attcatcata caaattacca aaaatgacag cttcgctatt aacactctca acacaagcag
   820321 gtgtttcgcc tttgtcaacc ttgtgtacac acatcgtaca agcttcaact gtacctttac
   820381 cccgaggcat atgttctttc tgattattta gtgtttcatg tacaaatgaa cgtgcgtcat
   820441 atggacaagc catcatacaa taacgacaac caatacataa atgcttatct accaacacaa
   820501 ttccatcttc acgtttcata gaggcatttg ttggacaaac atcaacacaa ggcggttctt
   820561 cacaatgctg acacataagt gcaagattac ttactttatt agtcgcttta tctttaatct
   820621 ttagtttttt aatccaacct ggtttttgac tagacgttga gcgtatctca gtaccccaac
   820681 cttgttcttg ttgacaagca ttaaccatgc catcaatatc agtctcagtt aacttattgg
   820741 tatcaatcaa caagccccaa cgctttttat tggtaacagg tgtttcactg acactagcaa
   820801 atgtggtaag tgtaatacca ctagcaacta tagcaacccc tgttgttgtt gcattcataa
   820861 ttttaataaa atctcgacga tttaatgctt tattcataat aaatcttccc ttagaaccgt
   820921 acgatgacaa ctgaaacaat caaaactaac accgactttc ttatgacaat ctgaacagaa
   820981 ttgaccttgc ttatcaactg aataatattg gttgtttatc ttattcttat tagcatgaca
   821041 cgacacacaa ccttttaaag aatattcatt tgttcgtata ccttgacgta aggttttatc
   821101 acgtttatga cgtaagaatt caggatgcat ttttcgaata attgaaggac tttcatgaaa
   821161 tactttaccg gacgctttaa tagaactagc ttgctcacca agattagcat attcgtcaat
   821221 atacgcaaat acactactta ccaacaaact taaaaaaaca accaaaaaac gattcataat
   821281 ttttatccag cttagattaa atcgaactat tcaccaagac ccatttgtat ataaccagtc
   821341 ggacaaacat cagcacaaat atgacaacca atacacttat tgtaatcagt atcaacatac
   821401 ctacctaacg ttgctttgtc tttcttaact ttaaataccg catcttgagg gcaatacata
   821461 acacagttat cacattcaaa acataatcca caagacatac aacgggctgc ttctttttgc
   821521 gcttcctttt cagtataacc aattaaacgc tcattaaaat tacctaatac gttatcaaca
   821581 tccactaatt tgtgattacg ttgattatgt tgttcatgat caaaatgacc taagaacaat
   821641 tctgtatgtg gaataatgga agcaaatgct cgatcttcat aattatgcac ggcaaaatta
   821701 gcactatctg ttgcagttgc aacgttagaa cctgacttat aagattcagg agcaaggtcc
   821761 cattctttta atttctccat taaatcaaaa taactaacat caaccttagg gcgagtatgc
   821821 tgttcgaaac ctgaaagata atcaccgata ctttcggcaa caactgatgc ttgaccaata
   821881 gcagttgtca ataagtgcgg acgaatcaca tcaccacaaa caaagaaacc tggcttatta
   821941 ggcacttgat aattcttgtc tgcgttaata aatccatgct tattaaagaa agaaatatct
   822001 ataccttcag aatcaacacc ttgaccaatt gcagaaacaa ttagttcaca ctcaatctca
   822061 aactcagaac ctttaattgg tgtactacca tcctcttcta aacgaatcat gcgtaacgca
   822121 gttgcacgac catcttttcc tgtaattact tcaacaggtt gtaattgacc ttgaatttca
   822181 acaccttcac gagtcgcatc atcaatttct tcttgtgctg ccggcatatt tacaacagta
   822241 gaacgtgttg ttaataatac atctgcgcct aagcgcttag aggtatcaac cacatcatgc
   822301 gttgtatcac taaaaataat atgttcagga cgatctttct cagcagcatt attaatatta
   822361 cccaaacgac gtgcaactga tacaacatca atagatgtat cacccccgcc aatacaaatt
   822421 actttacctg taatatgctt taaacgacct tggttatacg cttcaagaaa ggcaatacca
   822481 gaaacacaat ttgttgcctt accgcctgga ataggcaatg tacgaccact catagcacct
   822541 attgcaaata aaactgcatc aaactttttt tctaattcat caatagtaac gtcaatacca
   822601 actttagtat tcattctagt ttcaatacct gtattaataa tacggtcaat ctcataagat
   822661 aatacatcac gaggcacacg ataatcagga attccgtaca tcatcattcc acctagttgg
   822721 tcatattttt caaatatagt tacactatga ccttgacgac gtaatttaag tgctgttgtt
   822781 aaaccgccac aaccaccccc gataatagcc acttttttac cagtatcttt agcattaatt
   822841 gtaaatgtat aaccctcaac ttttgcatta tcgccaataa actgttcaac cgcattaata
   822901 ccaactgtat tctcaacttc attacgatta caaccatcct cacaaggtgc tggacaaaca
   822961 cgacccatta ttgatggaaa tggatttgaa tctgtagacc tttgaaatgc atactcttgc
   823021 caagatagtt caccagaagg cttctccata ccccgaacaa tatctagcca tccacgaaca
   823081 ttatgtcctg aaggacacga accttgacaa ggtggcgttt gggtaacata agtaggacac
   823141 ttatgggaag tatcttcttt aaaaatcttt tgactccatg gtactgtttt ttgttcatcg
   823201 ccatcattcg tatataatct aaatgtatgg ttatcacttt tagttggcac accatacggg
   823261 ttcttttgca tattaaatct ccttatattc gtttaaattt attctatttc taccataata
   823321 aaatcatcag tcaacttctg atttatcctc ctgaacttct atttttcgcc tgtccataat
   823381 aatcgcctca cttactaatt gatgaacact cacaatcata tatggatcaa aatcaaattt
   823441 aggaagcacc ttagaaaact gcgacttaca gatagcgcaa atagcagcta acgtattcac
   823501 accattgtct ttttcaactg ttttcagtgc ttgcattctt ggcactgcac cttttacacg
   823561 aatttccatt aaatcatctg ttagtaaacc tccaccaccg ccacaacaaa aagttgactc
   823621 tttaatcgtg ctacgctcca tatcaacata attattacat acagctttaa taacttcacg
   823681 tggcaaaata aattgaccac ctaaaatacc acccatattg gttgcgcgtg caacattaca
   823741 cgaatcatgg aaagtaaccg tacgatcatc attagcagac ttatcaaata ctaatttacc
   823801 cctttgaatt aaatcatgag tatattcaat aatatgttgt ggttgaggat aacgatgatc
   823861 taattggtcc tgtaattttt gactaaattc atcagcagca cctacaccta cacccgacaa
   823921 agtattccaa aaactataag caacacgcca cgcatgtcca cactcaccta ccataacccg
   823981 tgacacttct aaatcaagtg ctgctttacg aatacgtaaa gcagctttac gcatgacatc
   824041 ataagaacca ataaacatac cgaagttagc cccttcagag gcgtatgaac ttaacgtcca
   824101 actcactcca tcttgatgga ataccttacc ataaccaatt aacccatcga tatgaggctc
   824161 agcaaaaaaa tctgctgatg gagtaattaa taaaatttca gcaccttttt ggtctaatgg
   824221 atatttaaca gcaattcctc ctgtttcttc ttcaatttct tcctcaagat caagcaatgt
   824281 atcacgcaaa gctggttcag gcaaacctaa gttattacca atcgttaaag ccttacctaa
   824341 gatttgatta caatattttt gacctatacc aaccacatca agcacctcac gagctgccat
   824401 tgaaatttca gctgtatcaa taccgtatgg acagaatact gaacaacgac gacactgtga
   824461 acattgatga aaatagttat accaatcatc caacatatca tcgtctaatt ccttagcacc
   824521 taccaactta gggaaatatt tacctgcaaa agtaaaatgg cgacgatata cgcttctaaa
   824581 caaatcttga cgtgcaaccg gcatattttt tggatctgaa gaacctaaaa agtaatgaca
   824641 cttatcagta caagcaccgc atttaacaca tgaatctaaa aatacttgaa cggagcgata
   824701 tttagactta agctcaccta ttttatcaat agcaactttc tgccaattat ctactttttc
   824761 accaggaaat cctaatggat tttgaaattc ttgtgcagat ttgaatggtc cttcgccatc
   824821 cataacacct tcttttaact taggagtttc aagataagta ggtaatattg gaatgtcaaa
   824881 ttcttttacc atactattca tccttaccta gaatttgttc taattgtgtt gcatgttctt
   824941 gctcttgctt aagtgcccaa ggtgcaatat gacgctttga gcgagcatca tccacctgat
   825001 taagggttgg actaaaaaat atacctggta tgtgtaataa tttagaaatc ggaaaaatta
   825061 ccatcaacac aaataccaaa aaaatatgta ttaaaaaata tacttctgtt ggtagatttt
   825121 tccaattaaa actcactaat cctgaggtaa attcctttac cataataatg tctgtatgat
   825181 tgctggtaaa tgtcatgatc atgccactta taccaataat aagtagcata attaacatta
   825241 aataatcact cggggctgaa atataacgga tacgctcaac aaaaatacga cgtaatatca
   825301 atccaataag accaaacacc atcacaaaag cagcgtattt aaaagattga gttaataaaa
   825361 aaatatcagg taaatcatca ggccaaaaat aacgtatatg acgaattgaa atcaataata
   825421 aaccgatatg aaataaccaa ccaaacaacc aaatccattt atttgatcta aataaacttt
   825481 caaataagac tatttcacga attatacgca taaccacacc tttttgtgtt aacggagttg
   825541 gtgcaatagg aattttgaga ggagctggag ttataccaaa ttgatatatt tttttcacca
   825601 tcccaacaag aaatacaatt aacgaaatat aaaataaagc ggtaaaaaaa atacttatta
   825661 tagacatatt actctcaaat tcaatgaata aaatatcaaa aaacactcac caaagcaaat
   825721 gtttttatta cgtttgtatt gactcaaata caaccagttg gttttggcaa tccagcaaaa
   825781 cgacaacctt gcttaccagg accatatgga aataaagaat ataaatactt agagttaccc
   825841 ttatctttac ccatcctttt agcaatcgct ttagttaata cacgcactgc aggtgcaatt
   825901 tggtactctt caaaatattc acgtaaaaaa ttaattacat cccaatgttc ctcacttaac
   825961 gaaacatcat catcttttgc catttgctca gcaatttcct tactccaatc acctaaatct
   826021 accaagaaac cttcttcatc tacttttgcg cctaaaatat cagccatttt ttactcctat
   826081 ataaaaattt aagttaaacc caagaaaccg aagtcccatg ttcaacaacc aaatcaacaa
   826141 aacctgtata attgactaat ttaatattat caacaagttt tgaagaaact cctctcgctt
   826201 caacatcacc ttgaagcgca taaactctac cttgattggc aagattagca atcattgatg
   826261 agttaatatt ttttgttgca gaaataacac catcttcaat taataaaata acacttgtat
   826321 catcaattgt attaatacag gatttgagtg aatttcgctc gaaagatgat ttattaacag
   826381 tatgtaacat attcaattcc cttaaaaact aaaacataca tcttgtttag acataatttt
   826441 tgaaatctct aaattagaaa ccactttaac acttgatttt tcttcccaat tatcatcctc
   826501 atcttcatac actaaaggca ttaaatcatc tgcacttaga cctctttctt ctaaagactc
   826561 tgctgataca taaagtttat taatttcata atctcctaat gcatggaacg ttttagagaa
   826621 gttcttcata ccgataccat tagtattttg acctttaata atttgataca caccatcatc
   826681 aataaaagcc aaagagacat cttgatcaaa cgctgcagca accaatacca cttccaatga
   826741 ctcaattgca tacactgttc caaatgaaga acgacgattt aaatacataa actttttaat
   826801 tgacataaat tagtctccaa acactactaa acgatctgac tgaatacctg cttcaatcaa
   826861 ctgacctaaa ccagaaatac gaaatgctgg atgaatgttg ttaccatcaa taccattctt
   826921 gctcgcttca gattcatcta acattccacg acgaagcgct gctgctacac atacaacaag
   826981 ttcaggttcg ccattagcat tcttaatacc taactcagcc cactgattaa caatattacg
   827041 atcgtcttgt ggaggtattg taaaacgtga tgcattattc acaccatcat gatagaaaaa
   827101 tacacgaaaa atttcatgcc ctttttcaat tgctgcttta gcaaattgat acgctgtatc
   827161 agatgcttga tgctgatatg gtccttcgtt aatttgaata gaaatcttca taataacagc
   827221 tatttaaaaa cgaatatgtg cagaagaatt taactcatga cgtgcaccct tccaatcatt
   827281 gatatggaat ttagtaaacg gcaaacctgt cttctcaaaa aatgctggcc aaccaatacg
   827341 atcaacccat tcacccattc tttcccaatc acgagcatct tctttataaa cagataagat
   827401 atttttaacc acagcagtaa cttctggcca tcttggtgga ttattaggca aattagaagc
   827461 aactaattta tgaaacgaag gtttagatct agcatttgag ttcttaccac caatccataa
   827521 tgcaatctta gaatattcag gatcgttaat ttgcatcggc gggcatggcg gaaagcatgc
   827581 accacaacaa atacatttct tttcatcaac ttccaatgtt ggcttgccat taaccattgc
   827641 aggacgaata gcagcaaccg gacaacgtgc tacaacagtt ggacgctcac acacattagc
   827701 cactaaatca tggttaattt taggtggttt agtatgttga acattaagag caatatcacc
   827761 ttgaccacca caattaatct gacaacaaga agtagtcata tgtacacggt taggcatttc
   827821 ttctctagtg aattcctcat gcatttcatc catgagtgac tttacaatac cagaagcatc
   827881 tgtacctgga atatcacaat gcaaccaacc ttgagtatgt gaaatcatgg ttactgatgg
   827941 acctgtacca cctacaggga aacctgattc agttagtgct gcaattaatg actcaacttt
   828001 agcttcatca gcaaccatat attcaacatt agagcgcata gtaaaccgca catgtccatc
   828061 agcaaattca tcagcaatat cagctaattt tctaatagta tatacatcca tttgacgtga
   828121 agtgccgcaa cgaactgtcc aaatttcttc atgatttttt gaggtgtgat gtaatacacc
   828181 tggacgagga cgatcatgat aaacccattg tccataatta cgacgcatag ttggatgcat
   828241 gtattgaata ggatcagggc aacctgattc gataggcatt cttggtgctt cagccatttt
   828301 atttctccca atatattata aaattaggtg aaatctacat tcacctaaaa ggttgttatt
   828361 taaacgatat gattatgcac ttgcctctgc tttattttca aaccacttaa tagcttcttc
   828421 atcccatgta tccatacgaa cataagatga agtacgtgta gagttaacca tattaggatc
   828481 tacgttaagg ccgattcctt caagaaaatt aaccacacca atacgctcaa tcatttcacc
   828541 agttctttca tgttctaatg cattttcagc aaagaaatca atcacttcac ctgccaaatt
   828601 ttcaatttct tcaagattat ctgctgtttc cattttcata aatggcacaa ctactgaacc
   828661 aaataaatca ccaatcttaa gcgtacgctt accgcccata ataatcataa cgcctttatc
   828721 atcacctgtt gcgagaatag gttctatatc acctttagca atatatttat gagttaaggg
   828781 gctagtaaca tttaaacagt gcatacattt aacgcaattc ttgttatcaa tggtaactga
   828841 atcatcctca ttaagagtca tagcactagt aggacaacga gaaataatat tatcaacaac
   828901 ataactacgg cctttatctg ccaccataga ctgccataaa tattggttaa ctttaatatc
   828961 atctctccaa gtaccaataa ctgcaaagtc agcacgttga actgtattca tacaatcatt
   829021 tgaacaacct gacactttaa atttcatctt gtaaggtagt gctggacgat gcatatcatc
   829081 taaaaatgca ttaaccaatg tacgcaaaac cgcttgctca ttaacatttg acatctcaca
   829141 acgtgaagca ccgacacaag acattcctgt acgtactgca gggccagcac cacctaaatc
   829201 aaaaccataa tcattaaatg tattaaagat agtctgtgtt gtttcttcag tagaaccttg
   829261 taacatgatg tcacccgatt gaccatgtaa tgcaatcaaa ccagaaccac cattatctac
   829321 aaacatatca cacatatctc ttaataaagt tgatgtgtag tgcatccctg ctggtggttg
   829381 aacacgtaaa gtgtgaaact cacctgctgc aggaaactta tactctcctt tgtcatcttt
   829441 taactcatta aaacgtggaa tgataccgcc accataacca ataacaccaa ctgtaccacc
   829501 tttccaatag ccttttttgg ttacatatga agtttctagt gtacctaaca cgtcacgtgc
   829561 catctcagcg ccagcatgac tatcacttgc taatctttta aggcctgtaa cgaacgaagg
   829621 ccatggacca ttttccaact catcaaggtt tggtgtgtta tataactctg ccattttatc
   829681 tctccagtat attaaataaa tcccttggat gctctcacaa gaagatgttg aacgaaataa
   829741 attatacttc aataggagac aatactagag ctgattagtg gtactaacta ctatccctta
   829801 ggaggtagat tagtttaatc tttaaagaaa ccaactataa taaaaactaa tagaattagt
   829861 taataccatt gaaaattata ctaggcataa tagttaaaaa agtatctcat gttaaatatt
   829921 cattaacttt aacagcaaca ccacgacctt cattaatagc ccatacaact aatgattgtc
   829981 cacgacgaca atctccagca gtaaaaatac ctttttgtga tgttgtatat tgaccatatt
   830041 tagctttata attaccatgt tcatcaagct taatattagc atcatcactt aaataatgtt
   830101 caggagaaac aaatcccatt gatagtaaaa ctaattgcgc actccaagtt ctttcactac
   830161 cattcatttc catgaattct ccgttttgaa aatccacatt aaccgtattt aaaccaatta
   830221 cagagttctg gtcatcttta ataaatgatt tagtcattaa acaatattgt cttggatctt
   830281 taccaaatac ttctgttact tcagcgtgtc cataatctac acgataaata agtggccata
   830341 gcggccaagg attgtttgac atacgtttag ttggaggttt actcattaat tcaaagttaa
   830401 caattgatct tgcaccttga cgtaatgctg tactaataca atctgtacct gtatctccac
   830461 caccaatcac aatcacatcc ttgtctttag cggataaatc tgactcttct gcatatccat
   830521 tatccaataa gcttttagta ttatgagtta gatattccat cgccatatgc actccctgtg
   830581 cttgacgatt atccactaat aaatcacgtg ctttactcac acctgtagta agtacaagcg
   830641 catcaaaatc ctgttgtaat tgtattgtag taatatcctt accaacattg acatttatta
   830701 taaactcaat gcctgaattt tgcattaatt taacacggcg atcaacaaca tctttactaa
   830761 gtttcatatt cgggatacca tacattaaca aaccaccaat acgatcatca cgctcaaata
   830821 tagtaacatt atgacctatt ttatttaatt catctgccgc tgccaaacct gcaggaccag
   830881 aaccaataat agcaattttc ttacctgttc tgtactcaac tgtatatggc ttaacacgat
   830941 cttcatcaaa acctctatca ataatagctt gctcaatatt cttaatagta actgcagaat
   831001 tattaatgcc taatacgcaa gaaccttcac aaggtgcagg acaaacacga cctgtaaatt
   831061 ctggaaaatt attagttttc aataaacgtg ttaatgcttc ttgccattta ttatgataaa
   831121 ttaaatcatt aaattctgga atgagattat caactggaca accattctct gactggcaaa
   831181 aaggcacgcc acaatccata catcttgcgg cttgttcttg aagatgaact gcatcactat
   831241 aacctgtaaa aatttcaccg taatctttaa tacgcaaatc cacagaacga taagcctcag
   831301 tttttcgatt aaattcttta aaaccagtta tctttcccat gaataaataa atacttataa
   831361 tataaagtta aaaattatac catgcaaaag cataataaaa tttatatgtc atattcttgt
   831421 cttgttcact aaaaaaataa cggtataatt atttcctttt ttataaaagt tttttaaagg
   831481 aatactcaat atgaatttaa ttgaccaaat tgaaaacgaa caattaagat cagacctacc
   831541 tttattcgta tcaggtgata ctattattgt acaagtaaaa gtacgtgaag gtgaacgtga
   831601 aaggttgcaa gcatttgaag gcgtggtcat tgctaaaaaa aaccgaggta ttggttcagc
   831661 atttacagtt agaaaaattt ctcatggaga aggtgttgaa agagtttttc aaacccactc
   831721 aaaaatgatt gattcaatta aggtaaaacg tcgtggaaaa gttcaccaag ctaaacttta
   831781 ctatcttcgt ggtcttactg gtaagaaggc taggatcaaa gaaaaactcc agattagaaa
   831841 ataagcaaat ttcttttgaa aggtatggtt atatttagga tggaaaaata taacccacta
   831901 cgaatatata acttaatttc tattaaaacg tttaaatata atactcaaca cttaatattt
   831961 tataaacaat atcacccttt ggggctttta ctattacctt atcaccttct tcattaccca
   832021 ttaacgcact ggcgattggt gaatgacatg aaatcttatc tagggaaata tcagcttcat
   832081 cctcacccac aatttgatat gtaatttcgc tattatctac agaattcatt agagtaatag
   832141 tagtaccaaa aacacaacga ccatcttggc taagtttagt tacatcaata atctgcatac
   832201 gagaaagctt taattcaatt tctttaattc gaccctcaac aaagctttgt tcttctttag
   832261 cagcatgata ttctgcgttt tctttaagat ctccgtgagc acgtgctatc ctaatatctt
   832321 cgataatacg agggcgacta acatctttaa gtttaagcaa tgctgcttct aatgcttttg
   832381 caccaaaagc agtaactggt atattattca ttattaatat agtgattgaa gtttagttat
   832441 agtaaattta tcaatgactt ttaaaccatc taacatagca aatgcagctt ccactgtggt
   832501 agtaaacggt attttatgtg tcaatgcttg gcaacgaatt tctgcagcat cttccacacc
   832561 ttgagtatct tcagttgagt taataattaa atcaacacca tcatttttaa tcatatcaat
   832621 aatatgaggt gatccttctg atactttatt aattacttca cacttaagtc cagctgcatt
   832681 tagcatatcc ctattactac gtgttgaaac caaactaaaa ccttgtatta ataatttgtt
   832741 acctaaatta atcaactcat tacgatcaag tttacgcaaa cttacaaaca ccttaccatt
   832801 ttctggtaca cgactacctg ctgctaattg agccttatca aaggctgaag caaaatcttt
   832861 gccaacaccc attacttcac ctgttgaacg catttctgga cctaaaattg gatctacacc
   832921 taaaaattta ttaaatggaa atacagcctc tttaacgcta aagtgttcgg gtataatctc
   832981 tttggtgaaa ttctgagctt taagtgatac accagacatc acacgtgcag caatattagc
   833041 aagtggcacg ccaatcgctt tagaaacaaa aggcacagtg cgtgaggcac gtggattaac
   833101 ctcaataata taaatttcac cattttggta agctagttgg gtattcatca aaccaaccac
   833161 gtttaatttt ttagccatga gaataacttg agcacgcatt tcatctaaca ctttattggt
   833221 caatgaataa gggggtaatg aacaagcaga gtcacctgaa tgaataccag cttgttcaat
   833281 atgttgcata ataccgccaa tcaccacatt ttcaccatca caaatcgcat caatatcaac
   833341 ttcaatagca tgatctaaaa atgaatctaa taaaatagga gaatcatttg aaactttcac
   833401 tgctgtgtac atgtagtgct caagactgtc tttatcataa acaatcttca ttgctcgacc
   833461 accaagcaca taggatggtc taactactaa tggaaaacca atcgcattgg caatatcttg
   833521 tgcctgttct aatgaacgtg ccgtaccatt taacggttgc ttaagtttca gatcttgtaa
   833581 cattttagaa aaacgctctc tatcttcagc caaatcaata gcatctggag ttgtgccaat
   833641 aatatttgca ccacttttct ctaaagcttt agccaattta agtggtgtct gaccgccata
   833701 atgtacaata ataccatctg ggttttcaat atcaataata gctaaaacat cttctaaggt
   833761 caatggttca aaatataaac gatctgaaat atcataatca gttgaaactg tttcaggatt
   833821 acaattgacc ataatcgtct cgaatccatc ttcacgtaat gctaatgacg catgcacaca
   833881 acaatagtcg aattcaatac cttgtccaat acggttaggt ccaccaccta aaatcataat
   833941 ctttttctta tcagtcgggt tagcttcaca ctcaagctga taagttgagt ataaataagc
   834001 agtttgagtg tcaaactctg ccgcacaact atctactctc ttaaacacag acttaacatt
   834061 tagcgcatga cgacgttcac gcactgatga ttcgttacaa cagaataatt gtgccaaacg
   834121 cgcatcagaa aaacctttac gtttcaaaga aaacatctta tcagcatcaa tatcagttac
   834181 atttgtactg ttaatttgta attcggttgc aataatatct tgtatttgtg ctagaaacca
   834241 agagtcaact ttagataaat caaatacttc tttcaaactc atacccaatc taaaagcatc
   834301 agccaaatag aaaatacgat cacttcgagc tgaaatacat tcagaacgta tcttgttacg
   834361 tgcatcatca gcattcaaat caacaatagg gtctaatcca accttgtcag tttctagtcc
   834421 tcttaatgct ttttgcaaag actcttgaaa agttgaacct attgccatta cttcaccaac
   834481 agacttcatt tgcgtggtta aacgatcatt tgctccagga aatttttcaa aggcaaatct
   834541 tggtatttta gttaccacat aatcaatact tggctcaaaa gaagcaggtg ttttaccatt
   834601 tgtaatatca ttattaagct catctaaagt ataacctata gctaactttg cagctacttt
   834661 agcaatagga aaacctgttg cttttgatgc caatgccgat gaacgagaaa cgcgtggatt
   834721 catctcaata atagttaaac gaccattttc tggattaagc gcaaattgta catttgaacc
   834781 acctgtatca accccaattt cacgaagtac tgctaatgaa gcatcacgca ttgcttggta
   834841 ttccttatca gttaaagttt gtgcaggtgc tacagtaatc gaatcacctg tatggatacc
   834901 tataggatca aaattttcaa ttgaacaaat aataatacaa ttatcctttc tgtcacgaat
   834961 tacttccaac tcaaactctt tccatccaag aatagactct tcaactaata attcgtttat
   835021 tggtgataaa tccaagccac attcacaaat tttaacaaat tcatctttgt tataagcaat
   835081 accaccacct gaaccaccca tcgtaaatga aggacgaata actgttggaa aacctactgt
   835141 ttcttgtatg gtaaatgctt cttccatatt atgagcaacc gctgctttag gcatatcaag
   835201 accaattttt aacattgctt cacggaataa atcacgatcc tcagctttgt taattgcctc
   835261 ttttttagca ccaatcatct ctacacaatg cttatcaagc acaccatgac gttctaaatc
   835321 tagagcacaa ttaagagcag tttgcccacc catggttggc aacaaagcat ctggtttttc
   835381 tacttcaata atcttttcaa ctatacgcca ctcaatcggt tcaatatagg tgctatctgc
   835441 cattgttggg tcagtcataa tagtagctgg attagaatta actaaaataa cacgataccc
   835501 ttcttcacgc aatgcactac aagcttgcgc gccagaataa tcaaactcac aagcctgacc
   835561 aataacaata gggccagcac cgataattaa aatactacta agatcttgtc tttttggcat
   835621 tagtgtttta ctttaaatta aatcaaaaat catcatattc aataggaggg ttaccatcaa
   835681 agatatcaaa ttgtcttttt tgtaaaaaag aagaacgtgt tgcaatataa aaatcatctg
   835741 aatttttcag taaatctatt attggtgata atttgactct agtatcaacg gctctagtaa
   835801 gtagtaaagt tgtttcttca gtggcattta accatttatt tacatttaca ttttcggtaa
   835861 cattaatata agtacctact gaatcacgta tacttgatgg acccagaatt ggtaaaacta
   835921 tataagggcc acttggtacg ccccacactg ccattgtttg accaaaatct tcatcggttt
   835981 tttctatcca aatattactg gcaacatcaa ataaaccagc caatcctatg gtgctattca
   836041 ctaaaattct accgaatgta tttacactgt ccaacaactt aaattgcaaa agctcattac
   836101 ctaacgtaga cacatcatct aaattagaaa aaaaatcact aactctattt tgcatcgttt
   836161 tgggtaaaaa ttctttataa accttagcca caggataaaa aatattttca tctaaggttt
   836221 gattaaactc aaaaattgtc ctatttaacc cttcaaatgg atcaatattt tcagccataa
   836281 caattgaact aaatatcaac aacaaaaaac tcataaataa atttttcatt cgttcatttc
   836341 cctaataaat gtatcaaaaa aactactcat atcatgcggg cctggcgaag cttcaggatg
   836401 cccttgaaaa ccaaatgctt ttttattaac aatatgaata ccttgaatag aattatcaaa
   836461 taacgaacga tgtgttactt ctaaatcatt gggcatattt tcatctgaca ccacaaatcc
   836521 atgattttga gaagttatta tcacttgttt agtatgtaaa ttttgaacag gatggttagc
   836581 accatgatga ccaaatttca tcttttgcgt tgttgcacca actgccaagg ataataattg
   836641 atgacctaaa caaataccaa ataatggtat atcttttccc aataaaatct gaatattttt
   836701 aatagcataa tcgcatggct caggatcacc tggtccatta gataaaaata cgccatcagg
   836761 atttctttcc aatactttag tcgctgatgt ttgtgcatta acaacagtca atgcacaccc
   836821 cttatctacc aacattttta agatattttt ctttactcca aaatcataaa ccaccacttt
   836881 aaatttggta tttaactcat taaacttagt atttactaac gaataagaac cttgattaaa
   836941 ttcataagat tgagtagtgg aaactacttt tgctaaatct atatttttca taccaacaaa
   837001 taatttagcc ttagcaatag ctacttctgg gtcaatatca ttacctgtaa taatacaacc
   837061 tttaagtgat ccttgtttac gcaaatggcg cgttaacgca cgtgtatcaa tatcgctaat
   837121 agcaacaata ttattatgct ttaaataagc acctaaagat atatctgaac gccaattact
   837181 cgctattaaa gataaatctc gaataatcaa cccagataca tgaattttat cagactcttc
   837241 gtcaactaaa ttaatacctg tattaccaat atgtggacaa gttaatatga cgatttgttg
   837301 tacatatgat ggatccgtta aaatttcttg atagcctgtc attgaagtat taaacactac
   837361 ttcacccaaa gttataccat taacaccaat agactttcca taaaaaattt tcccatcttc
   837421 taatgctaat aaagcaactt gtaacactca atactcctga atgaaaaact ttgaaaattt
   837481 taccatatca ctctaacatt cacatatata aatcaaagtg atataataat acattataaa
   837541 aatacataaa aaatataatg aaaataattg ttgacaacat taaatgtgtt ggatgtataa
   837601 atatcatcac taaaaaatta atagcaacct ttaacactaa aaaagtgaat attaatattg
   837661 aacaaggtat tgtaaaaatt gacgtagata gtactaaaaa atctgaggtc gcccaagttt
   837721 tgctaaatct tggctatcct gaaataaatt caatacacgg ctttaattct accaaagcca
   837781 aagccaaatc ttttgtttct tgtaccatcg gcagaataaa tatatgacat ttaccctaaa
   837841 tggaaaacta ttaaaaatgg ctgataactt aaacgcatat gatttaatta ttcaactagg
   837901 ttatgaaaat caacgtattg cattagaaat caatgaaacc attatcccca aatctaaaca
   837961 tgctacattt gccctaaatg aaggagacat aatcgagatt attaaagcag tcggtggtgg
   838021 ttaaagctta ttgtataaaa aacatctcta attcattatc aaattaacta tttatatact
   838081 caacgttttc ataaaaataa attctcactc ttaaaaattc aatatctata tttctgataa
   838141 taaattatag tgaatagtcc ctaagtatag aaaatatgct aacatacttt ctattatgtc
   838201 attgcctaat ctaattcaac taatccactt atcaattttt tccgaggatt tattaacata
   838261 aaatatttgc tattcatggc aatcttataa tttctaatca attctacttc tacatactta
   838321 aactcatttt gataaattaa taatttcaac tgcataaaac acttttttaa actagtactt
   838381 atcttgaata attgtaatta gtgaattaat tgattgttgt aataactgat aacttttatc
   838441 ctttgctatt ttcttttgtc tttgattttt agttgtacat ggaaaccaaa ataactaatc
   838501 attaaagaag caatattaca aactactact taactaatat tttataccat ccagtctttt
   838561 tgaatttcat cagctgagaa tggcttaatg ttaagtgttt gcatagtgtc aacatctagt
   838621 tttatttcta tatctacgct gtcgtagcct ctaccttgag aatagcgtgc taaaatttta
   838681 gcagcgattt gtaaatctgc ttgattaggg tctccatcaa tcaatgctaa tggtccattg
   838741 caactagtgg gatataaatt agcatattga ttacgatagc cttctaagaa tttaacttct
   838801 ccttcttcac gagcaataat cattttaaaa cgtggatttg ggcgaatatg tctgccaact
   838861 ttaagcatca ttaaatcatc gagttgataa ttacgattac cacgagattt ccacatatcc
   838921 actagtttat ctgaatattg tttgtcagtt aaaaaacaac aaccacccgc aggtgtagca
   838981 taaccatcaa acccatattc ttttgctaaa aacatttgtg gtttgcgcgt acgccctgaa
   839041 aaatccaata atttttctct atctacccag ttctcaatct ctgctttagt aactggtaaa
   839101 tgttttgcac acaatggacg taataataaa tcattagcgc ctgattctaa ttgaataata
   839161 ggcatggttt ctttacgctg tgacatagga cgttgaccca cgacttcacc tgtaataata
   839221 aagtcaaatt catattcaac catccattct ttagcttttt taaccataaa gcccttacaa
   839281 tctagacatg gattcatatt tttcccataa ccatgtttag ggtttaacag cacatcacga
   839341 tattcttcaa taacatcaat aatatgtaat ttaataccta atttctccgc tacccataat
   839401 gcattattac gttttagccc gtttttcttt tgtttacgaa tggtattcgt atgcccttcc
   839461 atgcaaaaac cagtaaaaaa attaatgcct tctacatgaa taccttgatc taatattatc
   839521 ttagtgctta acagtgagtc taatccacct gaaattaatg atacagcttt aatttgtttg
   839581 tttgtcatgt ctattttctg gtataattgg aatagtgtta ttcgactttt ttatttaaca
   839641 ttaaatgtta aataaatgat aattaccagt atctaaacta tctctactta gtcttgaaaa
   839701 actgaaaaac actaaatagt acacattttt acacctaatt taacttaccc taatcatcac
   839761 tatataacac atttatcact taagaatcaa atttatttaa atggtaaaat aaattatacc
   839821 atatagaata ttgacaatac cttatcatat atcctcattt ataaccttga taaatatttt
   839881 tataaaaacc aagtaaaaaa ttaaggtatt aggtataata gatacatttg taatgtagaa
   839941 tacaaggcaa ccaaaatgga actaaaaaga acaggtaatg gctacttagt tgatccaact
   840001 atttggacag aggatattat gcataaaatg gccaaagaag acgaaatcga attaactaga
   840061 agcatggtta atcaaattct tacagctaga aagtattttg aggaaaattc atcagtacca
   840121 cctattagaa cctttgccaa agtcgttggt attgataaaa aaatcctatt taaagaatgg
   840181 ttaactggtc caatgaaacc tattactaaa tacggtggta tgccacaacc aacaggttgt
   840241 gtttaaccca aaaaaatttt taacttaaaa taaatcaaat taatgactta actgaggcaa
   840301 gtgccttgat taaacactca ggcttagtac ctccaccttg tgccatatct gaacgaccgt
   840361 caccctttcc cccgatttgt tttgctacat gattaagaat ttttctagct tgatactgct
   840421 tagttaaatc ttttgtaacg cctgtaacta aagatacttt atcattaatt actactgcta
   840481 atacaataac agctgaactt agtttatctt tgagtttatc aacaatatta cgtaaatctt
   840541 tgctagttac tccttctaca acagtagaaa gtaatttaat accttttact tcttgtgcct
   840601 gtacaatcaa atcatctccc tgattattag ctattttttt ttgaaaagta gcaatttgct
   840661 tttctaattc tttttgctgt ttaatcagtt gcgtcacttt tcctaccacc tctgtattac
   840721 ttgacctagt catttgtgca attttattca aactattttg aattcgattg tcaaattgat
   840781 acgcatcata gcctgttaat gcttcaatgc gccttacgcc agcagataca ctgctttctg
   840841 atataattct aaaaagtcca atatcaccaa gttggtttac atgagtacca ccacacaact
   840901 ccactgaaaa ttcattctta cccatagtta aaacacgtac agtatcacca tatttttttc
   840961 caaacagcgt catcgcgcct ttcttttttg caccttcaat attagtaata tcagtataca
   841021 cttttgtatt tcctaagatc ttacgattaa ctatgctttc aattctttcc aagtctgatt
   841081 taacaatcac cttatcatat gagaaatcaa aacgcaattt ttcactacca accaaagaac
   841141 ctttttgcat taccgcctta cccagaacaa tatgaagtgc agcgtgtaac aaatgtgttg
   841201 ctgaatggtt tctagcaatg catttacgag attttttatc aacattagct tgtaccgcat
   841261 cactcacttt taacacgccc ttatttaaaa caccatgatg ctcaaatgca cctgattttt
   841321 gcttattagt atgatccact ctaaactcaa cctgcatatt agaaagtata cccttatctc
   841381 caatctgacc acctgattca gcataaaaac ttgactgagc taaaacaaca attccatggt
   841441 cacctacttc aattttttca accaattcat tattgttaat aatcgcctga attaaagaga
   841501 cattttttaa ttgtttatat cctaaaaact cagttctctc agcaatgtca acaccttttt
   841561 ccgatatttt aaaatcgcta gcttgtctag cacgatctct ttgtttggtc atttcaacct
   841621 caaaacctga catatcaata gttaagttac gctcacgagc aatatctgat gttaaatcca
   841681 ctggaaaacc ataagtatca taaagtttaa aaactatttt tccattaatt tcactacctt
   841741 taaaattagt aattacttct tctaaaatac tcattccttg gtctaaagtt ttcgaaaaac
   841801 gctgttcttc acgctttaat accttttcaa ctttggataa ggcttgttct aattctggat
   841861 aaacatcctt aaattctagc gctaatatag aagccaaacg ataaaaaaat acttttccaa
   841921 tacccatctt atgcccatga cgaataccac ggcgaataat acgacgaagt acataacctc
   841981 taccctcatt tgaaggaatt acaccatcaa caatcataaa agcagcagaa cgaatatgat
   842041 cagtaatcac acgaactgag gcgttgttat ctttaatatt attgaattta ggggttaaat
   842101 tcacaacagc cttgacaaga ttttgaaaac catctgtatc gtaattatta tttttatgct
   842161 gtaacacagc cactaaacgc tccaacccca tacctgtatc tacacaaggt acggctaatg
   842221 gctttaaata accatcttct tgtttatcaa attctgtaaa tactaaattc caaatttcaa
   842281 tatatcgatc accatcttca ttggcgtgtc ctggtggacc accagcaata tgctcaccat
   842341 gatcataaaa aatctcactt gatggaccac acgggcctgt atcacccatt tgccaaaaat
   842401 tatctttagc gccacaacga gagatacgat tcttaggaaa accaatttca ttaacccaaa
   842461 tatcttctgc ttcattatcc tgatcaaata cactcaccca aagatttttt ttaggcaaat
   842521 ttaactcttt tgttagaaat tcccaggcat aatgaatagc ttcacgttta aaataatcac
   842581 caaaactaaa attgcccagc atttcgaaaa aagtatggtg gcgtgctgta taaccaacat
   842641 tttcaagatc attatgcttg ccaccagcgc gcgcgcaacg ctgaaccgat acagcgcgag
   842701 tatatggacg cttttctata ccactaaaca catctttaaa cggcaccata cctgcattaa
   842761 caaataataa agttttgtca ttatgaggaa taagcgatgc actagactca attatatgac
   842821 cttttgattc aaaataatct aagaattttt gtctaatttg tgcggttttc attttgctaa
   842881 aagtacttaa tcaaaactgc atattatacg ccgtaagtgc ctatataata agggaaatgt
   842941 ctcctgcgcc ttggcgaata atgttaatac tagacaaaga taaatcaatc acagtggtag
   843001 gttctagcgg acaatatccc ccatcaataa taacatctac acgcttctct aatgaatcat
   843061 atacatcatc aatatcaaag aactcacaat ctttaatgat caatgatgtg tttattattg
   843121 gctcatttaa cacatctaat aaagcttgaa ccaagccatg attagatact ctaaaaccaa
   843181 tggttttttt cttagcatgt aacaatcgat taggcacgtc acgtgtacct tgtaaaacaa
   843241 atgtgtacga ccctggaagg attctcttaa gcaatctaaa agaaatatta tctagcttag
   843301 catattcacc aatatgtgct aaatcacgca tcattaaggt aaagtagtgc tgttttgaaa
   843361 gattacgaat acaacgaata cgctctaatc catttttatt acccaatgtt gctcccaatg
   843421 cataaccaga atctgtagga tagacaataa ccgcaccacg acgtaactca tcagccactt
   843481 gttcaagtaa acgtatttga gggttttttg ggtgaatttc taataatttt accatatcca
   843541 atttttccat attgcttgct cataattagg taaatcttgt aaacaaccaa tttgtactct
   843601 ttgatttgac cagccatgat agtcagaacc acttgacgct aataaaccta actcacctga
   843661 ccattgacta acaagtataa tttcatcgag gctactcatg gccgttacta cctcaatccc
   843721 agtacaacca ttaacagcta aatcactcat catacgttta atttgagtgt gtgttaccct
   843781 ataacgaaga ggatgtgcta acactgctac accacctgca ctacgtatcc atccaattac
   843841 ctcatcaaat tgtgcccact taacgcttac actacctgga ttattacccg ttaaaaaatt
   843901 cctgaatact gatttcatat ttttacaaat accctcttga attagcattt gagcaaaatg
   843961 tgtacgagta attatccctg ttttagtaat ggctttggtt ttttccatag caccaataat
   844021 gccagctcct tccaaactac acgctatttt ttcactacga acctctcgaa gctgttgatg
   844081 ctttttaagc ccagtctgta atattttgtt atttggatta atcttcaacc caagaatgtg
   844141 aatcgtcatg ttattccatg tggctgatat ttcagtacca aatacaaatt gtaaatttaa
   844201 tttattcgcc tcataactgg cttcagcaag tccgtcaatc gtatcatggt ctgttaatgc
   844261 aaccatgtca cagttttgtt tgttagctaa acgaaccact tcagtaggcg ataaaatccc
   844321 atctgaataa tacgaatgat tgtgcaagtc gataaccata agttgtttat tataatctat
   844381 ctgttttgca agcgtaatta gctataattt caatataatt acttaataca aacactatgt
   844441 gcggaatcgt tggaggcatc tgtaaataca atatcacccc aattttactt aatggattaa
   844501 agcgcttaga atatcgtgga tatgattcag caggtattgt agtcttgtca aataataaca
   844561 aattgaatcg tgtacgcgca gtaggaaaag taattaacct tgaaaccaac attcaaaaac
   844621 aaaattcaaa aatacaaggt aatgttggta ttgcacatac tcgatgggca actcatggtg
   844681 aaccatcaac acaaaatgcg cacccccata tttgttttga tactgttagt gtggtgcata
   844741 acggcattat cgaaaacttt cttaaactca agcaagaaca aaaagcacaa ggctatgctt
   844801 tcacttcaga tactgatact gaggtaattg ttcacggtat ccatcaagcc ctgaaaacat
   844861 caaaaaattt acttcaagcc actcaaaagt ctattaaaac ttttgaagga gcttatggtt
   844921 taggagtgat atcaccatca tatccaggac atatagttgt tgctagaagc ggctctccac
   844981 tcattatagg tattagtaat gaaggtaatt tcattacctc agatcaagta gctttattag
   845041 gtattactaa aaaatttatt tttttagaag agggggatat cgccgatatt acgcttaatt
   845101 caattactat ttataaccaa gacgatgaac aggttaatag agttattaaa atttcaaatc
   845161 ttaacagtaa acaaattgat ctaggtgatt ataaacatta tatgcaaaaa gagatttttg
   845221 aacaacctca agcaattcgt gacacgctag aatcacgaat taccaaagat actgtgtcac
   845281 tttctgcctt tggtcataat gctgaaacta ttttcacaaa tataaaacac attcaaatta
   845341 ttgcttgtgg tactagttat aacgcaggat tagtagctaa atactggctc gaagacattg
   845401 caaaagttcc aaccaatatt gaagtagcta gtgagtatcg ctatcgtaat ccagttgtac
   845461 ttaacaacac cttattagtt acaatttctc aaagtggaga aactactgat acactagaag
   845521 cactaaaatc tgttaaacag catcacaata atattcacac attaaccatt tgcaattgtg
   845581 cagaatcttt cttaacacga gaatctgaac ttaccttatt aacccatgct ggacctgaga
   845641 ttagtgtagc atctaccaaa gctttcacca cacaattagt atctttagca ttattatcag
   845701 tcgccattgg aaaatgccat aaacaagtag ataaaaaaca agaaactgct attgtagatg
   845761 gtctaaatcg cttaccaggt ttgataaaaa aaacacttga acaagaaagt caaattattg
   845821 aacttgcaca atcttttaaa aataaattta atgccatttt tttgggaaga ggaacaatgc
   845881 atgctattgc catggaaggt gcacttaaac ttaaagaaat tagctatatt cattcagaag
   845941 cttttccagc aggtgagctt aaacatggac ctatcgctct cattgatcaa gacacacccg
   846001 ttattgcaat tgcacctaat gatcaactat tagacaaact aaaatcaaac ctacaagaag
   846061 ttaaatctcg tggttcacag atgattgttt ttgaggatga aatgtctaat gtaactccaa
   846121 tgcaaaatat gactgtcatg tcaatcacgc ataatcttgg tataattaca gcacccatta
   846181 tttttaccat tcctttacaa ttactaagtt atcacgttgc attaatcaaa ggtactaatg
   846241 ttgacaaacc tcgcaactta gctaaatcag taactgtaga ataaatatta tgatcaacat
   846301 actaggcttt gattctgact ttgatccatc tcttttagat cgaattgtta atgagaaaaa
   846361 aaagattggt tattacaact tacctaatca agataccact tatattaatc attacttgaa
   846421 gcaattaaac aagagacaaa atttaaacag tattagcgat gttgttgtta tcggtattgg
   846481 tggatcaagt ttaggtgcta aagcagttta ccattttatc agatccatta gacaattaaa
   846541 acggaattta cattttatgg atagtacaga ccctattact attgccaata tttgtaatag
   846601 tttaaacatc agctcaacac attttattgt tatctctaaa tcaggatcaa ctattgaaac
   846661 aatcgcgatc tataaacata ttcttgcaat aacaaaaacc attcaacttt cacactttcc
   846721 ctttacattt atcacaggta agagctcact actagcacaa catgctcgaa aagttaacgg
   846781 tttaattatt aatatccaac aaaatattgg tggtagattt tcacttttaa gcagtgcagg
   846841 cattatccca ttagcattaa ctggtacaaa aattgattgc ctgctaaaag gcgctgcaaa
   846901 aattaaagat agttttttta atcaaggcta tatgcaaaat ttattgctta aaaaggcaac
   846961 cttttatgcc aacaatgctt caaactacaa tattaatgct ctgttctctt ataccgattc
   847021 tcttaaatat tttaatgatt ggtatgcaca attatgggga gaaagtttag gtaaaaaaca
   847081 aaaaaactca gtctttcatg ttggattaac acctattggg ctaactggac ctaaagacca
   847141 gcactcattt ttacaactat tatacgaagg aatacgagat aaaagtgtca catttattaa
   847201 actgaaaacc tttgagaatc accaaaaaat acctaatatt accttagaaa aattagaaac
   847261 atttaaccta attaatcaag ttaaattttc gaccttgatt aatatgcaag ctgacgctat
   847321 tatagaatct ttaaaaaaac acacaagaat ccctcttgat gaaattacct tgcaaaaaca
   847381 agatgaattt agtatcggtc aactaattta ttactatgag ttacttacat cacttgttgg
   847441 aaacttactt aatattaata cttataatca accaggcgta gaatttggaa aaaatattct
   847501 cattaagaaa ttacaacaac aattatgatt aaaaaatgtc ttttccctgc agcaggatta
   847561 ggtactagat ttttacccgc cacaaaagca gttcccaaag aaatgttacc tattttaact
   847621 aaaccgttat tgcaatacgc tgtagaagaa gcacttagtg ctaatataac caatatagcc
   847681 atcgtaacta ataaaaacaa acgagctatc gaagaccatt ttgatcaagc tttggaattg
   847741 gagttgcaaa ttaaaggaac gcaaaaagag gaactactaa aagagatcaa taccgtttgc
   847801 aactatgcta cattcactta tgtcagacaa aaacaaatgt taggattagg atatgcaatt
   847861 ctcactggta aagcactaat tggtaatgaa ccttttgctg ttcatctagc cgatgactta
   847921 tgcacatcag aagaaggcaa tagtgtacta tatcaaatga ttaaaatata caacaaatat
   847981 caatgttcaa tagtagctat cgaagaagta cctatgaatc aaattcataa gtatggtgtg
   848041 attgttggtg acttgattga taatactaat aatacgtatc gagttactaa tatggttgaa
   848101 aaaccaacac caaaaaatgc accaactaac atggctatta taggtcgtta tatcttaacg
   848161 ccagatattt ttaatatcct taaacaaact aaaccagaca aaggtggtga aattcaaatt
   848221 accgatgcac tacttactca atcaaaacaa ggtaacgtta ttgcctataa atttaaagga
   848281 aaacgttttg attgtggtag tattcagggc tacattaaag caacaaacta ttttgctaaa
   848341 ctacaaggta tcatgtaaaa atttgatgta tcccctagaa tagataatac tcattttcta
   848401 agtattttat aaaaatcctt agctgctcca acaataaatt actaatttac actataactt
   848461 aaagcctgac acaggttgta tcaataataa gcccaattta ttttgataat agttagtgat
   848521 aataagctct atgatctaat aatcgcttta aataatttta aggcaaaata tcttcttaaa
   848581 cttttattta ttaaatgact agcatccaac taattaatag ttatttaagg aaacttattt
   848641 atctaagcaa ataaatcaga gtccagtgtt atactatcaa ctactttact aactaaatta
   848701 atattcttaa gtgaataaat agacaattta tcaacaaata tatttactta aaatataaaa
   848761 cacaccacaa ttccaaaaat agttatttta attctaaata tgattatata gttcagcttc
   848821 aaaacttttt acaaattttg caacttcttt atacatacta ttctatccta aagagcacaa
   848881 tactaagcat taccacttga tattttttag ctacaaaaaa agcatagtat ttaaatagaa
   848941 ataaacaatt agttacaatt atcacaataa taattaaata gttcttagta atatatcata
   849001 tatagtcttt gattgatata aaatattctg ctaataattt agcattatga aaaaataatt
   849061 agataaaaat gaataaagtt aacattatat gcataaagtg gggtgataag ttccccgtta
   849121 aatacgttaa tagactcttt ggtatggttt ctcgtcatct ttctatacca tttcggttta
   849181 tatgtttcac tgaaaataat acaggtatac gaagcgaggt agaaatacag gatctaccag
   849241 aattagattt accgcttgga ttactagaaa gaggttggag aaaattaact atatttaaaa
   849301 acaactttgg caacttatct ggttctactt tatttctaga tttagacata gtggtggtgg
   849361 gaaatttaga tgaatttttc acttttcctg gtgatttcct aattgcccat gataagaaaa
   849421 aaccaaaaaa aatagaaggt aattcatcaa tatttagatt tgaaattgga aaatactcaa
   849481 aaattttaag ttattttgaa aaaaatttcg agctagtaaa aagtgaagtt cgccatgaac
   849541 aagcatactt atcacgagaa ctccacaaac aagataaatt aaaatattgg ccagatgagt
   849601 gggtaccaag ctttaagtat cgttgttgtc cttcttggat aaaatcttgg tttcaagcac
   849661 catttatacc caagaatgct aaagttattt tatttcatgg cttacctaat ccacctgaag
   849721 caattattgg atgcagtaaa aaatggtatc gacacatcca gccatcacct tggattgaga
   849781 aatactggaa agtttaataa atgctaaaga actcctactt atgttatagc attaaataaa
   849841 aatctctaat atattacctt atatggataa acaattatct aaattagaaa cccaattcat
   849901 acaaataaaa ataatatata atcatcaaat tcaacctaaa atattacaat cttaccaaca
   849961 acaattaaaa tactcagcga tttattatac atctttctct ataaaagaaa ttaactgtat
   850021 tcttaatttg tataacactt ggaaaatagt atcaaaccat aattccaaga cgtatattgt
   850081 attagaaaat gatattaaaa tacatagtaa ctttaaaaat ataattgaaa ctatatgtat
   850141 aaatttggga aaaatattgt aattgacatg tttggaagat aggtatgata aaaaaagaaa
   850201 gaaaatatgt taataatgtt atgtttattc attatcaaat atgggtacta ggaaatatca
   850261 actcaatcta tgaaaaatta tctactcaaa tatttctaaa tagaaaacaa atatttttgc
   850321 ttcacaatat acaaacttgg gacttgaatc aatgctacat ctcttgccag aattttagaa
   850381 taaagggtta tcaacaatct cagtcaaaaa ataataatgg gacgcaaaga taaaagcaaa
   850441 tttgagaaat ggttttcatt aactcgtcat caaagacgat ttggtgcaaa acatttatcc
   850501 aaacatatta atgttgactt caaacaccaa aaaaaacaat ttattgtcga tgatggaata
   850561 atatatacgt atggcagtcc taagaatatt gaagaacatt ctaatgcttt aaaaaatgaa
   850621 ttctctggac aaagtgaact ttgtcatact catgcaaaac ttattatcct aattagaaga
   850681 gaatttgaaa caaaaaaaca ttttactatt tttgaaaatc tttggcatga agaaacaaaa
   850741 ttcttgctta aaagtttaaa cacacgttgg ctactttctg caattaatac ttttgcagat
   850801 tgctctaata atgacgcaat cataggttta tctgtagcat gctcatgctt gttaatcact
   850861 atcgaaatac aagaaagtga acgtttcatc attaattcga aaaataataa agatgataaa
   850921 gaaaaaactg atagactaaa taatgaagaa agaataatgc tttttgatgg tatttcaacg
   850981 tttaaatttg gaacttctga cacaattaga aatatgcgat ggcgaattga taaagcagca
   851041 aaaataaatg ttgcaggtaa aatactatta gaagtattta aacgattgca aaagtttgat
   851101 actatttata aacgtgcaaa agatagacac actcgtgata agactggatg gtggtaaatg
   851161 gatatctttg ttattaatct atcaagtgct attaaacgcc gtcaatttca agaacaacaa
   851221 ttatctagat taaaactaga ttatcaaata accaatgcca ccaccataag tgatattaat
   851281 aataaaacct atcaaaaaca ccattatgac tggcagagac ccatgcaaaa aactgaagtc
   851341 gcttgttatt tttcacatca aacactatgg tcaaaaattg ttaaaaaaaa tagaatggct
   851401 ttaattttag aagatgatgt tttactgtca aaacataccc ctagcatact aacaaaatta
   851461 gaaaagtata ccaatttcga tatggttaat ttagaagttt ttaatagaaa aaaatatgta
   851521 gcaaaaaaat ctcaaccaat cggtcatcat caattatttt acttatatca agataaagca
   851581 ggagctgcag cgtatgtatt atacccaaat ggtgcaaaaa aattattgca acagcagcaa
   851641 aaaagtggta ttgctctagc agatgcacac ttacataatt gtctagaatt gcaatcttat
   851701 caaatagaac cagcttgtgc agtacaacta atgttttgca aaaaatacga tattaaacaa
   851761 cacagtacag caattagtca atcattcatt aggtatgaaa ataataataa ttccatcttt
   851821 gtttttaaaa taaaaagaat aactgtacaa ataaaattag ggatacgtca attaagtttc
   851881 atccttaaag caaaaaaacg ttatattaaa ttaaataata aagattttaa ataagactta
   851941 cttttaatga aaaaaaagaa tgtagctatt gttatcccaa ctttacaggg aaatggagcg
   852001 gaaagaatgg tattgactct agcagaaggc tttattcagc aaggatatac tgtcaatatc
   852061 gtattaacac tcaaaaggtc aattgaactt aaatcaagca gacaattaaa aatacattat
   852121 tttaaaaaat attatcgctg gataccaaaa attatcagag gtatattttt agcaccaatc
   852181 ttagataagt ttatcgttaa taggtgtgac aacccaaatc ttgttctatc taatttactt
   852241 ccatctgaca gaatactatg ttatagtaaa cttaatactt atttaattat tcataacacg
   852301 ataagtaagc aaaataataa ttttgctgaa atgagaagta tatatactaa aaaaccagtt
   852361 atttgcgttt cccaaggcgt caaaactgac tttgaccgat tctttaatag tcgatttcca
   852421 tcatattaca tatataatcc tattgatgtt gattttatca atcaggaatc tattaaattt
   852481 aaaccaaaat atcatgatta tttagttcat gtaggtaaat ttaaaaagca aaaaagacat
   852541 gatattttaa ttaaagctta tcaccaaagt ggtatagaaa atccacttat cctaatagga
   852601 aaaggtcatt taaaagaaaa atacaagaaa ttagttaata acttagattt aaacgaaaaa
   852661 gtaatttttg ctggatttca acctaaccct tacccattta tcaaatatgc taggttaatg
   852721 gtgttatcat cagattttga gggatttggc atggttataa cagaagcatt agcattaaaa
   852781 acaccggtaa taagtacaaa ttgtccatca ggaccatcag aaatattacc taaaaataat
   852841 cttgtaccag tcaatgatat tgaaaaatta gctcaattaa tgcaacaagc caataataac
   852901 ccattaatat tttcacaccc attaaacaaa aagttctacc ttgattttac tactaagaaa
   852961 tatattgata taattaatgg ttaatagatt ttttacaata aaacagaagg tctaaagata
   853021 cacatctaaa agatacagaa acacaaaatt aatattgtac ttgatacacc aaatccctcc
   853081 aaaaaaactt cttattataa tactctacac acctaacagc caaatctcct gtcattaatg
   853141 agcttaattc aatataaaat acgtttcaag caacatatcg ttatctatca acatttccca
   853201 tcctttgtaa tcatacaaat aaggtaacaa aacacgactc ataaaaactc tataatatca
   853261 aataaacatt tgttctaaaa aaagatattt ttgtataaaa aagtagcttc tactggaata
   853321 gtaacccttg gtaaagatat ggacaaaaaa aatataaaaa atttttaata aaatactaaa
   853381 gttaatataa ctaattatta aaaaagtact taaaattata tattctgttt cctacacata
   853441 atgattatca aaacttattc attagcctat tctttaatac caatagttct tccttataaa
   853501 atttaacaaa aaatctattt atcagattat aataagtcaa taagtgtgat acacgagttg
   853561 acattaatac caagataaga attttatttc tgttattatt aactagagat ttaacactct
   853621 caagacaaac aatacactta atataataaa acctaataat gcatcaaggc cattacatta
   853681 aatactaata taaaactata tagaacttat caaggttaat acaaagttat atctattctt
   853741 ataaatggtt aatatcattg tgattaagat tatgctagaa aatagagtaa ttaaaactct
   853801 ttacgagaaa ctatgatagg caaaataaca aaactaaaat caatcataca gagtcgttag
   853861 aataatttaa attacttaaa taaattttct ttagataaga aacaaaataa atacctaggg
   853921 ttaataataa taaaatcctt taatatatta gagattagat attctaattc tagataaaag
   853981 tagtacatta acaatattcg cataaataat tgataatcta atacttatga ataaaaataa
   854041 cacttacaca aactttatca gaaaccaaat tgatattgat ttagaacaaa aattacatac
   854101 ttctattcaa acacgcttcc cacctgaacc taatggttat ttacatattg gacatgctaa
   854161 atcaattttc ctgaattttg gtttagcaaa agattataaa ggacggtgta acttgcgatt
   854221 cgatgatacc aatccaacaa aagaagatat taaatttata gatgctatca aagaagatat
   854281 taaatggctg ggattttcat gggatggtaa tattaagtat agttctcact attttaaaca
   854341 gttttataaa tatgctactg agcttattaa taaaaattta gcttatgttt gcttcttaga
   854401 ttcagatgaa attcgtactt atagaggtac cttaaaaaag gttggacaag atagtcccta
   854461 tagaaataca tcaattgcaa aaaatttaga attacttgca aaaatgaaag caggtaagtt
   854521 tttagaaggt gaatgtgtat tacgaggcaa aattgatatg aggagctcat ttatgtgtat
   854581 gcgtgatcca actctatacc gtattcgctt tgacaaacat caccaaacta gcaatcaatg
   854641 gcatatttac cctatgtatg attttgcaca ttgtattagt gatgcaattg aaggagtgac
   854701 tcactcttta tgcacattag aattccaaga taatcgtcgc ttatatgatt ggatactaga
   854761 aaacttagat gattttaata agcctaatcg tccacaccaa tatgaatttt cacggctaaa
   854821 tttagaatat acggttatgt caaaacgtaa attacaactt ttagtagaaa ataaactagt
   854881 atctggctgg gatgatccac gcatgccaac tatttcagga cttcgtcgtc gaggttatac
   854941 taaagttgca attcgtgagt tcacaaatag aatcggtatt tccaaagttg ataatattac
   855001 agatatgaaa attttagaag ttgctgtacg tgataacctt aatattgtag cacctcgtac
   855061 catgggtgtt attaatccaa tacgtgttat tattgaaaat taccctgaag gtaaacttga
   855121 aaccctacag tcccctaccc acccacaaaa taaaacaatg ggaaaacgtg atatattctt
   855181 ttctcgtaag ttatacattg atagagcaga ctttaaagaa acagttccca ataaaaaatt
   855241 tagacgacta gcaatcaata aagaagtgcg tctacgatct gcttatgtca tcaatgctac
   855301 tacttttgat actgatctta acggtaatat taccactgta tacgcaacat acgatcctga
   855361 tacattagga aaaaacccta aagatggtcg taaaattaaa ggagtaattc actttgttga
   855421 agccactaaa gcacttaaag cagaatttag actatatgat cgattattca tacttaaaga
   855481 ccttggaaaa aataataact ttgaacaatt acttaacaca caatcactaa tcatcactta
   855541 tggtatggta gaacctagta tggctaatag taagcctgaa tttgcttatc agtttgaacg
   855601 cgaaggatat ttttgtagag acaatcaatc aagtaataaa ctaattttta ataaaacaat
   855661 caatttacat gatacttgga aaagttaata ctttatacta aaaaacaatt taattaaagg
   855721 tttacaataa ttaatggaat ttcaaggaaa gataacaata gattactcgt taactacaca
   855781 ttgaaatata aactatctta ttaaaaatat aaataactct ttgtcaaaaa gtatctataa
   855841 tttagggtta ataaaactaa atatttatca aaataatatc tgttaatact acttatccaa
   855901 gcttttaaaa taaattggtt attaccattt agtataatta gaaatcaata aaataaatca
   855961 aatcacattg caactatagt cgctttacgg tattttcttt gaagatttgg taatattcaa
   856021 agaaaatcat agattataga atcaaaaact taatatgaaa cttttataaa cctataaaac
   856081 aagacatttc tactaatatt ggtaataaca aaaacaataa taagattaat taaatcaagt
   856141 tgtaattatt tgatttagcc atgttgatac agtattaatc tcgttatatt tagttaaatc
   856201 agtttgtaaa ggtgtgattg acacgtaatg attagtaata gcatgaaagt ctgtccctac
   856261 gccattatca gcctctttac cattctcacc aatccaataa agtgatgaat catttttatc
   856321 gataacactt tgctctgaca tatgacgctt tcctaagcgc gttgtttgaa accctttaat
   856381 atcactaaaa atcacatctg gaacattaat attcagtaca gtaccatatg acaaatgagc
   856441 atgagatatc tgattaatta attgtctgat tacaatacct gctgtcttga aatgctgacc
   856501 tctccaactt gctagtgata tcgataatga tggtaaaccc aaaaatcgtc cctctattgc
   856561 tccagcaaca gtgcctgaat aaatcacatc atcgcccaaa ttagcaccaa agttaatacc
   856621 tgtcactact aaatcaattt cttcatttag gaagccacac agagctaaat gtacacaatc
   856681 acttggtgtt gcatcaatac aataaacatt attcgatatt tgaattggcc tcaaaggctt
   856741 atcaagtgta agagaactac tagcagctga tttattttca ctaggcgcaa ctacaataac
   856801 ttcgtgttct tgtgctaaag attgggcaag ttctataatt ccttgagctt gataaccatc
   856861 atcattacta actaaaatct tcatctttaa ttagtaaact attgtatcac gactgtatca
   856921 caaggataat tctatctttt ttaacatcaa cctttaccag accgccatta gttaatttac
   856981 caaacaataa ttcatctgct aatggcttac gaatttcttg ttcaaccaaa cgtgccatag
   857041 gccgtgcacc catcttagca tcataaccat gttttgcaaa ccatgctcta gcaatatcag
   857101 acacagttaa agaaacctgt ttattttcta atgctttctt tagttcaaat aaaaatttat
   857161 tcactacata aacaatagtt tgttcgttaa gagtattaaa ataaataact tctgataaac
   857221 ggtttctaaa ttctggtgtg aataattttt tcaattcagt ctcataatct aacgagcggt
   857281 cctgttcact aaaacctatt gatgcacgct gaatactttg tacaccagca tttgatgtca
   857341 tcaccaaaat tacatttcta aaatcaacct ctcgaccgct ggcatcagtc atcttactat
   857401 tatccatgac ctgtagtagt agattaaaaa tatctgcatg agctttttca atctcatcaa
   857461 gtaataacac cgcatgtggg ttagcattaa ccacttcagt taacaaacca cctttatcat
   857521 aacctacata acctggtggt gagccaatga atttagaaac tgagtgacgt tctccatatt
   857581 cgctcatatc aaaacgtaac aacttaatcc ccataatccg agctaattgc ttgcaaattt
   857641 ctgttttacc aacacctgtt ggacctgcaa aaagaaaaga tcctattggt ttatcaactt
   857701 gcgccaaacc cgaacgtgat aacttaatag ccgtagacaa actatccaat gcacgatctt
   857761 gtccaaacac acccaattta agctctgatt ctaggttttt taataaaaat ttatcatcat
   857821 tggtcacttt attagacgga atacgtgcta atttagaaat aatattttca atatcgccca
   857881 caccaatatt aatcttacgt tttgatttag gctgaatttg ttgataagca cccacctcat
   857941 caattacatc aattgcttta tctggcaaat aacgattatt tatataacga tgagacaatt
   858001 caacagcaga tcttaacgct gccgctgaat atttaacttt atgataattt tggtagtatt
   858061 ttttaagacc ttgtaaaatt ttaatagtat ctgctacaga aggctcatca atatcaatct
   858121 tttgaaaacg acgtgataat gcatgatctt tctcaaatac ttttcgatat tcttcataag
   858181 tagttgaacc catacaccta agtgtaccat cagccaatgc aggctttaac aaattagaag
   858241 catctaatga cccaccagaa acactacctg caccaattaa ggtatgaatt tcatcaataa
   858301 acaaaacagc tttcggtatt ttttctaaat cggttaatac tgctttaagg cgtttttcaa
   858361 aatcacctcg atattttgta cctgcaataa gcacaccaat atctagtgaa taaatactaa
   858421 ctttctttaa aatatctggc acttttcctt caacaatttt caaagcaata ccttgcgcaa
   858481 tagccgtttt accaacacca gaaagaccta caaataataa gttattttta cgacgtctag
   858541 ataatacttg cactgtgcga ataatttctt tttctctacc aagaagagga tctatttgtc
   858601 cagacttagc tttttcacac agatttgttg tataagtttc caatgaggat tgtttgattt
   858661 tttccttatc tgattccact cttggctcac ttgtaataga ttctggagtc ctatttaaaa
   858721 tatcctccat ggcatctaaa cgtgaaatat tattaagttt taacaaataa acagaatgag
   858781 aatccttttc agaaaaaata ctcacaagta tattcattgc atataccgta tttttttgcg
   858841 cagattgtac ttgatagata ctacgttgta aaacacgctg gaaacccact gttagaacaa
   858901 tatcaacatt agaatcaagt gcaataagtg gtgtatgtga atcaatataa ccttctaatt
   858961 catcacgaaa ttcatcaaca tcaacccgtt tattatttaa taaagtaacc atctcatcga
   859021 tattaagcag cgctaaaagt aaatgctcaa ccgtcacaaa ttccaaacga ttattacgag
   859081 cttgtgtcat cacataatta atttcttgtt gtaatcctgt ttcaatcatg gttttattat
   859141 atctccaatt tatataatac acacattaat aactgttaat tttttgcgta taaattctat
   859201 cacctgtgat attttaatcc ctacaatatc aaataataag taccacaaat tacatagtta
   859261 tataatcatt atttagcaac aatatttgga atttattggg cttcttaatt ctgattgtaa
   859321 agattataat aataccttta ccatactaat tagctgattt tctctttaac aacaacaata
   859381 caataaccaa taccattagt gtcggtattg aggcgcttag aaaatgatta taattaaacg
   859441 taagtgacaa tacaccgatg atacgcgaag ctaactcaaa aaataaactc atcattagcc
   859501 ctaaaaaaat ttttttacca agtgacgcat cacgaagtga accaaaaaca aatagcattg
   859561 aaaataatat catcgcaacc aaagtaacag gcatcataaa acgtttatat atttctattt
   859621 caacaatatc agctacaaga ttattatttg tcaaaaaact catttgctta taaagatgcc
   859681 aagtagagag ttttcgagga tctttcttca gatttttgat cagtttttga ttaaatgata
   859741 tttgaacact gtatttttca aaataatttt tagaaaacgt tgtcaattct ccattcttac
   859801 ttaattgata atgaataggt ttgttaagtt ctaaattatt cccattaaaa gttgcattat
   859861 cggaatatat aatagaatcc aacacacctg gtgcacgtaa tttaataaaa gtaatatctt
   859921 gaaatgattt agcatcaaaa tctttcttaa catgaataaa aagcccattg tctttcagcc
   859981 agaactcttg ttgatttcta catgtcatat tttgttctag tgctttagaa cgcaaacact
   860041 ctgcatattc agtggttatt ggtgcaacta gttcacctat aaggataata attgcaataa
   860101 acattaacgc aacccaaaca acaatatttg aaatttgcat aattgatacg cccgaacttc
   860161 taataataac caactgagaa gtagatgcta aattagtcaa tgccaaaagt gatcctaata
   860221 aaataataac tgatgaatgc gaatacataa ccgcaggaat attcaaaatt atatattttg
   860281 ttgcttcaaa tacggtgtaa ttatattgtc ctataaattt aacttcatca agaaaattaa
   860341 aaaatgaata aacacctatc caaaccaaca ttacaattaa tgtataaaaa gccatagttt
   860401 taacaatata aagtgttaag attttcatta aaataatatt cttacataat agaattattt
   860461 aactttaata tcatgatgaa caatattcac cttaataaaa ttcttattct tgattttggt
   860521 tctcaatata ctcaacttat tgcccgtcgt gtacgtgaaa ttggtgttta ttgtgaatta
   860581 tctcactatg atataaatag tgactttatt aaaaagttca atcctaaagg tgtcattctt
   860641 tcaggtggtc ctgacacagt aacatttgat aattctgcta gagcaccaag tattatattt
   860701 gatcttaaca taccaatact aggtatttgt tatggtatgc aaactatggc gatacaactt
   860761 ggcgggcatg ctacttcagc tgataaacat gaatatggtt ttgccaaagt tcgttcttgc
   860821 aactactcgc cactactaaa tggcattaat gacggaggtg acgatttatt agatgtgtgg
   860881 atgagtcacg gaattgaggt aaaacgatta ccagatgggt ttaaactaat cgcttctaca
   860941 gatagctgta atatagcagg atttgccgat ataaacaaac attattatgg cttacaattt
   861001 catccagaag ttactcatac taaacaagga aaacacattt tagagcgttt tgtcagtgat
   861061 atttgtcaat gtaagaaaaa ttggacaaca gataatatca tcactaaatt agtgaaggac
   861121 cttaaaaacc agattggtag tgctaatgtt ttattaggtt tatctggtgg tgtagattcc
   861181 tcagtagttg ccatactttt acaacaagca gtaggcaaac aacttacttg tgtatttgtt
   861241 gataatggtc ttttacgtct caatgaaggc aataagataa tgcaaacctt tgcacaaaat
   861301 atgagcgtga aagttatacg tgtcaatgct caggaaaaat tctacaatgc actatcaaat
   861361 gaagacaaac ctgaagcaaa acggaaaatt attggtcatg catttattga agtatttgaa
   861421 gaagaagcta gaaaacttaa taacattcaa tttttagccc aaggtacaat ttacccagat
   861481 gttattgaat cagcaggcac aaaatcaaac aaaaccaaag ttattaaatc acaccataat
   861541 gtaggtggat tgccaaacag tttacagtta acattagtgg aacctattaa agaattattc
   861601 aaagatgaag tacgaaaaat tggtgttata ctcggtcttc caactcatat gcttaattgt
   861661 catccattcc caggacctgg attaagcata cgtattctag gacaagtaaa gcaagaatat
   861721 gtcgatattt taagacaagc tgatactatt ttcatagacg agttatataa aaataattta
   861781 tacaacacag ttaaccaagc ctttgctgta ttcctaccta ttaaatcagt tggcgttact
   861841 ggagatgcaa gacgctatga ctatgttatc tcactacgcg ctgttgaaac cattgacttt
   861901 atgacagctc gttgggcaag actgccttat gattttctag atttagtatc taatcgaatc
   861961 atgaatgaaa ttccacgtat ttcacgtgta gtctatgata tttctagtaa accaccagca
   862021 actattgaat gggaataaac acagtagctt ggatgacact tgctattgaa caagcaaaac
   862081 aagcacaaca aataggtgaa atacctgttg gtgcaatttt aatacaaaat aatcaattaa
   862141 ttggaggggc gcataatcaa acaattttaa acaatgatcc aactgcacat gcagaaatac
   862201 aattattgcg tattgcaggt aaaaaattaa ataattatag attatctggt acaaccttat
   862261 atgttacttt agagccttgc actatgtgtc taggtgcgat agttcatgca cgtatatcat
   862321 gtattgtatt cggtgcttat gacaaaaaat caggtgcttg tggatcgtgt atagatttac
   862381 taaataatcg atgttttaac catttaatta gcattaaaag cggtattcta gctgaccaat
   862441 gcaaaaatct attacaggac ttttttaaaa ataaacgaaa aaatacttaa taaaaacaac
   862501 ttaattttta aactgcatac attccgccat taacatgtaa tgtctgtgct gtaatgtatg
   862561 caccaccgtt acctgctaaa aataatactg cattagcgac ttcataaact gtacctaaac
   862621 gattcatggg aatttgctga gatacagcta ctatttgctc ttcagataat gtattaatca
   862681 tatctgtttc aataaaacca ggggcaatcg cattaattgt aatattacga gaacccactt
   862741 cacgggccaa tgatttggta aaccctatta tacctgcctt ggcagcggca taattagttt
   862801 gacctgcatt acccatagca cccacaacag aagcaataga aataatacga cctgatttct
   862861 tcttcatcat tccacgcaat accgcttttg acattttata gactgaagtt aagttggtat
   862921 taataatatc atcccattca tcctcacaca tccgcatcaa taaattatca cgaataatac
   862981 ctgcattatt aactaatata tcaataatcc cataagtacc aacaatagac tttatcatct
   863041 tagcaatttg ctcattatta gtcacattaa gtttcatacc tatacccgta acaccgctat
   863101 tctttaatac tatgctaatt gcacttgaac ctttattact ggttgctgta ccaataacag
   863161 ttgcacctgc cgctcctaaa gttaaagcaa ttgcctgacc aataccacga cttgcacctg
   863221 ttactaatac gatttttcca tctaaattat tcatgataaa atttccttta aagttatttc
   863281 tatactagtt ggatccaata tagcattaac cgttaatgat ttctcaattc tttttgttaa
   863341 acctgtaagt acttttcccg gaccagattc aattaatttt tcaataccca tattatgcat
   863401 cgcttgaata gtactagtcc ataacactgg attatgtaat tgcgcaacta atttagattt
   863461 tatgtcgtca acatcagttg ctttaagtgt atcaaaatta tgaagcacat caatactacc
   863521 ttgattaaac cgaaccacat ctacataatt cttaaactca actgccgcat cattcattaa
   863581 tgaacaatgt gatgctacac taactggcaa tagcactaca cgtttagcgc ccctaatttt
   863641 caataattga caagtagcct ctacagcttc tttattgccc gcaataacca cctgccttaa
   863701 tgaattaaaa ttaaccgctt caacaatgcc actacctgaa taatctaaac acaatttaac
   863761 tacaacacta ctctctaaac caagaatagc tgccattaca cctactcctt taggcattgc
   863821 cgattgcatc aattctgcac gttttctaac taacttaatt ccatcactaa accctaaaga
   863881 accagatgct actaatgctg tatactcacc taaactatga cctgccatac aaataggcaa
   863941 taaattatac ttatacgtaa gcgctaaata agttgcataa cctgcagcca acatagctgg
   864001 ctgagtattt tgtgtttgat taagggcatt tcggtcttgt tgtgttaatg tccaaagatc
   864061 aaaacccagt gcatcacttg cctcagtaaa tgtttctttt acaacaggaa aataactggc
   864121 aagttctgac aacataccta aagattgtga cccttgacct ggaaatataa tggcgtattt
   864181 cataaaattt aaaacaaatt caattgcctt attttaatta ataaaaaagc gcttgaaaag
   864241 cgcttttcaa aataatctaa atgcacaaaa ttatgtaatt tcaatagaaa tatattgata
   864301 cataaactta ccttttttag aaaatacaac cctaccatcc attgtggcaa ataatgtatc
   864361 gtccttgccc ttacgaacat tagtgcctgg atgaaattta gtacctcttt gacgtactaa
   864421 aatattacca gctagcacga cttgtccacc aaatctttta acacctagac gttttgatac
   864481 tgaatctcta ccgttgttag tactaccacc tgctttttta tgtgccataa aatactctct
   864541 tatgcattaa ttttaacaat ttcaatttca gttaacaatt ggcgatgacc ttgttgtttc
   864601 attgaatgtt tacgacgacg gaatttgagt atgtgtactt tctttccttt tccttgtgaa
   864661 ataatttttg cttcaacagt tactttagac acaaaaggtg ttcccacctg aatatcatct
   864721 ccatcagaaa ctattaatac ttctttaaaa gtaactttct taccaggctc aatttctaat
   864781 ttttcaattt ttagaattgt gccttgttta accttaaatt gttgaccacc tgttttaata
   864841 actgcgtaca taactaattc taaatatact ctgcttaaaa tagcgtgatt atacgtgaac
   864901 gtttaaattt gtaaagtttc tttaataaaa ttataacgta taattaatat ttcttcttta
   864961 aatggacttt taatacatga ctatttttga aaccaacatg ggtaatattc atattaacgt
   865021 tgatattaaa aatacaccaa ttagcgcaca aaactttatt gattatgtga ataatagatt
   865081 ttatgatggc actatttttc atcgtgtgat taaagatttt atgattcaag gtggggggtt
   865141 tacaaaagat atgatccaaa aaaccaccaa aactaacatt aaaaatgaag ccaaaaatag
   865201 ctttaaaaat aacaaatatt cattagctat ggctaggact tctgcgccac actctgccag
   865261 ctcacaattc tttatcaaca catcaaaaaa ctcatattta gattttcccg gacaagatgg
   865321 ttggggttat tgtgtgtttg gtaaagttgt taaaggtttt gaagtgattg ataaaatcaa
   865381 ccaagtatct actagcaaca aggatgaaca tagtgatata ccaaatgact ctgtaattgt
   865441 taatagggca tataacgctt aacaatgagt caaatattta tcatagcaga tttacacctt
   865501 actgttaata aaatagaaaa aactcatctt tttattaagt tttgtcaaga acaagctgtt
   865561 atagccgatc aactttttat tcttggagat ttatttcata cttggctggg tgatgacttg
   865621 tcaattaatt attatcaaaa agttatcttg actttaaaaa aactaagtct taaaactaaa
   865681 atttttatca tgactggcaa tcgtgatttt ttactaggca ataactttgt taaacaaact
   865741 aattgtattt taattaacac tccttattta cttaaaacta gtaaacaaca atatttacta
   865801 acacatggcg atgaattatg cactgatgac aagaaatacc agcgtttaaa acgcgtatta
   865861 caacacccaa ttacaaaatt tatttttctg catttaaaga caaaactacg tataaaaatt
   865921 agtaacaaat tacgccaaaa tagcatcaaa gctcaacaaa gtaaatcact taaggttatg
   865981 gatgtaaata tgacaagcgt caatcaatta atgcaaaaat accctggtgt aaatcttatt
   866041 cacggacata cacaccgatt agacacccat gttaataata actttactag atacgtattg
   866101 ggagaatggt caaacaacca agggaatgca attaaaatta atcatcaaca actaaatcga
   866161 cttaaaatta gcactacaat caactaaatc aacagttgtt acttttagtg ttattttttc
   866221 atctagctta ggcaaaattt taaacctaat ctgagttatc atacctaatt caggaatcat
   866281 aagcaatgtt ttattaccgc gtatatccac tacaaaacta tcaccttgcc ataatggatt
   866341 atcaagtaga taaacgcatt tataatggtc attactagaa cgtattgtcc taccaacact
   866401 agacatagta gtattatgaa taccaataat ctttttaaca tcctccttgt ttaatgtatc
   866461 ttcaccttta ataaaccgac taagctgttg atgtgcgaat aaatcaagat accttctaag
   866521 tggactagta atacgtaaat atgccttaac tcctaaacca aaatgtggta aattcttgat
   866581 agatgtagct gagcgtttaa aaaactttgt agctttaaat gactcagata aagataatgt
   866641 gtcttgatta tctaatattt cttgtgaaaa ccctccttta tcttgaattg tataaggcat
   866701 aacaatatta ttatcaacag caaattgtgc aacaacacga ccagccatca ccatcatttc
   866761 ggccaccaat tcacgacttt tacttaatct ttgttgtgta attaacactt ggccctgcct
   866821 aaacctaata tcaacattgg gcaaatttaa actaattgca ccatttttat atctatattg
   866881 tttgtgtgct tttgtgatgc tttgtaattt tgataaatat tcattagaga ccaacatccc
   866941 atctgcatta tcataactaa tattagtcac tttaattata ctacgaacca cttcaacgtt
   867001 attaatctca cctaattcta aagtaaaccc tatcgacaaa gcatgtgatg tttcggtcaa
   867061 tcccaatgca cacatcttag tcacagaaat aggtaacatg tggataattt gctcaggtaa
   867121 atataaatta gaagcacgct tttgtgcata agaatccaac tcagaaccag cggtagcaat
   867181 caaagataca tcagcaatat gaatccaaat cttatcgcca tcaacactaa ttgcatcatc
   867241 agcatcattt gaatcaaaat tatcaattgc ataactagat aaatgcgtta aatcaacccg
   867301 atcaactttc actatactag catcaatttg atcatcttta agaatattat tacgagttgg
   867361 ataaggatta aaacctggct taaaataatt cagatttaat aacaatctat aggcagattc
   867421 aggtatattt tctataccaa tattagataa aaccttagca tgcttagatt gatttaacgc
   867481 cactttctca atatccctaa tatagggtaa atcttgttta tccaatatat tgttagcaat
   867541 attatccgca caatgcttaa gattcttagt ctcaataatt ttagcatcac gtttagttcg
   867601 gatactttca acttggtaag ttgggcgtat aaaaactttg tctttttgcc aataaaaata
   867661 caacccatct tcaattaaaa cacaactaca ccaagcattt ttagcattat actcatcaaa
   867721 taaccattgc gttacttctt ctaatgttaa tacttcttct tgtagatctt caagtacaga
   867781 cacatctgca tatgtacacg tgttatctac ctggacaaat tcagaatgaa taaaacggaa
   867841 atcttttgct cgtaccaagc gcgaagaacc atcagcaaac tctagtacaa atttatgtat
   867901 cgtttgctta ataatacgtg caggcttacc tttataggat actaaagcgt taatcaattt
   867961 agagtctagt ttaatatttg tgcataagca gtagaatcca ttaaatcaac aactgaatga
   868021 gacttaaatt taactaacca accatcatca taacaactag aattaaccaa ttctggttcg
   868081 tcatcaagtg cttcgttagc ttcgataatt tgcaaatcag caggtgaata aacaccacta
   868141 gccgctttaa cagattcaac cacacaaaac tcatcatcaa tagatacttc atcatcaaca
   868201 ttaggtaatt ctacaaatac catatcacct aataatgctt gtgcatgatc agtaataccc
   868261 atagtataag tgtcatcacc attatctaaa atccactcgt gagtctgtgt atattgtctg
   868321 tcatctctta tttcactcat gctgttctcc taaatttttt tcaagtaatt ttttcttact
   868381 tatttaaacc aatacaatac cattacgcac aaatggcggt tcaactattt tagcgtaaac
   868441 ctgccttttt cgtatctcaa tttcacacac accaaggcta cctttcggta cgcttgccag
   868501 tgcaattgcc ttacctatag taggtgaaaa tatacctgac gtaactttac cttcacctag
   868561 actagtcatt actttttggt ggttacgaat cacaccttta ccttctaaaa ctaatccaat
   868621 aatggttttt ttaacaccct tatcttttaa cgtctctaat gcatcacggc ctataaacgc
   868681 acgattttcg ttgcttaaat caaccgtcca agctagtgct gcttcaagtg gtgaaaccat
   868741 atcattcatt tctaaaccat ataaacttac tcctgcttct aaacgtaaag tatcaaacgc
   868801 acctaaacca taaggtttaa caccagcctc aagcagcatt ttccaagtaa attttgccgc
   868861 atttaaaggt aacataattt caaatccatc ttcacctgta tagcctatac gtgcaataaa
   868921 taacttacct aaactagctg cattaaatga ttttaattca ccacaaacct cttctactcc
   868981 tggtatagca gagaatactt tttcccttgc atttggacct tgtacagcaa tcatagctaa
   869041 atcagatata ggctcaacca atacgtcaaa actatttgct tgagtgttaa tccaagccat
   869101 atccttatcg gtagtccttg cattgataac catgcgataa tattcattat ttcgacaata
   869161 aacaatcaaa tcgtccacta tgccgcctaa ctcatttaac atacaaccat ataaagcctt
   869221 tccttgtact cttaacttat caacatcatt agcaatcaaa acttgcaaga atgcttttgc
   869281 ttcaacgcct ttaaaatcca ccacgctcat atgtgaaata tcaaacatac ccgcatcatg
   869341 gcgtacttga tgatgttcct caatttgaga accataatta agtggcattt tccaatccca
   869401 aaaatcaacc atatttcctt gtgactctac atgtatttga tacaatggtg tttgtttcat
   869461 tattttttat cttctttaat atatttctta ataaaaatta tcattatgat tatcaatata
   869521 agtgttagtc ccatagtgcc aaataattta aaattaaccc aagattcttc agcctcttgg
   869581 gcaataatac aaagattact cattgctata ttcgtgcaat ctaacattgt caattcaatt
   869641 ttaggatcaa gttcagtaga agtaaacaat gcctctctag cacttaaagc aatattaaca
   869701 tagtaagcat taacaatcgc aatacctata aaaccaaatc cccacaacca actaagctga
   869761 caccatacat ttatcggcaa atctaattct tttcctaaca tcctttgtaa taaggttttt
   869821 ttaccaatcc acatacttaa cactaacata aaagcaaata ccacatacaa cacactaact
   869881 ttccacatta aaaatgcagg atctcttaaa acaagcgtta ctcctcctaa aactcccaat
   869941 aaaccaaatg ttattaaatg cgtattttcg aaccttccta tttggaaacg tacaattatc
   870001 atctgcaaaa aagtcgcgct aatcatggca taaattgcca tatacaaacc catcacttta
   870061 taaacaacaa aaaatagaat aataggaaaa aattcaagta agaatttatt catttattct
   870121 aaatgctctt tagagcaata tgctttattg ttttgaataa tcgcctcatt tctagggata
   870181 tgaatcttgc aaacactaca agccaacatt atattgctag aagatttctg cttaatacga
   870241 tcaattggtt tcctaaactt ttttaataac caaaaaccca tccaaacaaa tagaacaata
   870301 ataattaact taataatccc catacaatgc tactctgaca aaaagtgaaa ttttacccat
   870361 gcttagtata taattccttt tttttacgta tcaataattt acaaactgcc cgggtggtga
   870421 aattggtaga cacacaggac ttaaaatcct gcggccttaa cggccatgcc ggttcgattc
   870481 cggccctggg caccattctt aaattaattt tttggacaac caatacttga tgacgaaaaa
   870541 ctaactatat tttctatatt ttactaacaa ataattatgg agtattagtt atctttacaa
   870601 ccactctgtt caaaatattt aagtaatatt tatcaaaaaa tttaccttaa cttggctaag
   870661 atttcgtata attaatacat tctaattcag gtactttatc atgcaaaaac agattatttc
   870721 aaccaacaaa gcccctaaag caatcggcac ttattctcaa gcagtatgta ttactggcgg
   870781 atctatcatt tatttatctg gacaaattcc tttaatacca gcaacaatgg aaataataaa
   870841 tggagatatt ggtgaacaaa ttaatcaagt ttttaaaaat ctaatagctg tttgtcgtca
   870901 atctaacggt gacttaaaag atattgtaaa acttaatatc tacctaactg atctaaataa
   870961 ttttccaaaa gttaacaaaa ttatgtccac ctattttaat gaaccatatc cagcacgtgc
   871021 aatgattggt gttaatgaac tacctaaaaa atctatggta gaaatagatg gggttatggt
   871081 gatagaaccc tatgactaca catactaaac actccatact aaaataactt gatatagctc
   871141 tcatagtttg tttaaataaa ctccacctat tttattttat gtatcaatta tctaattcaa
   871201 ttattatatt agatggatta ggtccaaaaa cacaacaaaa actaaatgcc attggcattt
   871261 ttaatttgga gcatttattg tttcaattgc caacacacta tcaagataaa accaaactag
   871321 ctaagctaaa ccaagtccaa ataggtgatg aagtattaat tcaactaacc ataaagtata
   871381 ccgaacaagt atcaactcat cagaaacaat tgttatgcta tttatctgac tctaatcacc
   871441 gaaacttatt acttagattt ttttatttta atcaatacca aaaacaaaac tttattcgtg
   871501 gtgatatcat ccaatgcttt ggtgaaataa aaatgggtca aaatagctta gaaatacaca
   871561 atcctgaata tcgattaatc tctaaaggac aagctaattt actagaaaaa acacttagcc
   871621 ctatctatcc attaaccgcc aatattcgtc aagcacaaat gaagaaatgg atagatactg
   871681 cattagaagt tcttcaacaa tcagatttgt ttgataattt taaaaatcta acaaacaata
   871741 ccatgcctac tcttaaacag gccttaaata cattacacca tcctaaagtt gatgataata
   871801 taaaacaaat cgctaatttt aagcactttt cacagcaacg cttgattatt gaagagttat
   871861 gtacacaacg tcttagtcta ctcaaactca aaagcaaacg taaatccaaa atatccaaca
   871921 tatttaaaat aaaaaataga ttaactcaaa aagcattaga caccttaaaa tttcaactta
   871981 cccaagcaca acaaagttgt attaatgata ttaattcaga tcttagctca aaccatccta
   872041 tgcttagact attgcaaggt gacgtaggat caggcaaaac tattatagct gtatttgctt
   872101 gtttacaagc aattgagaat ggctttcaaa cgactatcat tgcacccact gaaatactag
   872161 ctgcacaaca tttacaagga ttctcaaatt atctaactcc tttaggtatt gatattgcgt
   872221 ttttaactga ctcacaaagt gcaatacaaa aatccaaaca acttgaaaaa attaactcag
   872281 atacagcaag aattatcatt ggtacacatg tattattaca aactaaagtt gtttttgata
   872341 aactaggctt agtaattatt aatgaacaac acaaatttgg tgtacatcaa tgcttatctc
   872401 ttgtacaaaa atcgcataat acacctcacc aactagtcat aactgccact cctattccaa
   872461 agtcattaac cattagtgtt tatgcagatt tagattactc aataattgat gaattaccca
   872521 ctggtagaac accaactaac actattgtac ttggaaatga taagaaaaat aaagtaattg
   872581 aaaaaatcaa acaagtttgt aatattggta atcaagtata ttgggtatgt acattgattg
   872641 aagaatcaga agtactccgt actgaatctg ctaccaatac ccataattat ctaaaaaaaa
   872701 atttagaagg gttaactgta gtactaatta atgggaggat gcaaaaatat aaaaaatcca
   872761 atattatagc acaatttttg aaaggtgaga ttgacgtttt agttgccact acagagattg
   872821 aagcaggtgt taatatcatt aatacctcac tcttggtcat tgaaaattct gaaagactag
   872881 ggcttacaca attacaccaa ttacgtagtc gcgtaggacg aagtcttgac gctagtattt
   872941 gtattctaat gtatcaagca ccactcagtt ataatgctat tgaacgactt gacatcttaa
   873001 gaaaaacaaa tgatggattc aaaattgcac taaaagactt agaacttcgt ggccctagtg
   873061 aaattctagg aacacagcag ataggcataa ctaatatgaa aattgctaat attgtacgtg
   873121 ataggtattt actcaaacaa gtacagtctt actcaaagca attcttaaaa ttagacaaaa
   873181 acaagcaaca aatacttatt actcgttgga ttactaatga taacagcaca tatagtaata
   873241 tttaaaagta tctgattgac gtaaaatact acaattatgt ttaatacaaa aaatttaata
   873301 tggacaaact taaatcaaat cagaaacata cctgaccaca ttcttacttg gcttgatgat
   873361 tatcaatcct tgactgctaa actaaaacaa aaatttaatc gtttttcagt caatatttta
   873421 tcacaaaaaa aatctattcc acatgctgat gaaatagaat tgcttgattg gcacagccaa
   873481 tttgttgtac gcgaagtaga acttttagga aatgatcaag ttattgtatt tgctaggtca
   873541 atcatcccca ttactgacaa cacacaaaga ttattaaaaa ttggtagtca ccctttaggt
   873601 gaaatgttgt ttaatgatat aaatattaaa cgtggtcaat tacaaattac ccatacacat
   873661 ggaacttggg gtagaagatc tatctttacc attggttcaa ctcaagtatt agtgagtgaa
   873721 ttttttataa aagattcata aaaactaatt agttaatttc accttttgat atataaatta
   873781 atatatttga tgatattctt tataatctct agtcatcaat ccataattga aatagttaac
   873841 ttattaacct tgacaattta acaggtaata ttgataatat tgacctattt ttagtcaata
   873901 tctttgatat agaatttaaa aaattatcta ttattacgct taatcttaat cttgtaatct
   873961 atttacacta aaaaataaac aagttctaat tttgacaatc aacaaaaaca caaccagcca
   874021 atggctattt ataacaagat taaaaataca aaaaaatcaa tcgattgaaa acatacaaat
   874081 aacagataaa ctcattgaat gatttaacac ggtaaactac aaaacagtat ttgctgtttt
   874141 cagtgttctt aactccacct ctattttaac ggtaaaatag tacatattat gttgcttatg
   874201 attgacaatt acgactcatt tacctataat ctagtacagt attttggtga gttaggacaa
   874261 gccgttgaag tgtaccgtaa cgatgaaatt acaatacagg aaattgaaaa acttatgcct
   874321 gaatttttgg taatttcacc aggcccttat gcaccaaatg aagcaggaat ttcaattgag
   874381 gccattaagt atttttctaa gaaaatacca atcttaggtg tatgtctagg gtttcaagct
   874441 atagttcaga cttttggtgg aaatattatt ggtgcaaaaa aaattatgca tgggaaagtg
   874501 tctaaaattt atcataccaa caaaggtgta tttacaagcc tcaagaatcc actcaatgca
   874561 acacgctatc attcattagt agcacaacaa tcaactttac caaaatgctt tgaagttacc
   874621 tcatggacca aaaataacaa aggagaagta gacgagatta tgggcgttag acacaaagaa
   874681 tttgctaccg agggagtgca atttcacccg gaatcaattt taaccgaaca gggtcatgaa
   874741 atactaaata attttttaat aaggagggct ttataaacca tggaaatatt tgaattctta
   874801 tttgctaatg agcaaatatt tacaactatt acgcttatat tattaattgc tttatttatt
   874861 ggtaatattg ttgttgataa attaaaaaaa tataaagata ttgaccctaa tggagcggta
   874921 acacttatgg ataataacaa tcttattcta ttagatgtta gagaagaaag ggagagaaag
   874981 gtcggatata ttgatggtga tattcacatt ccacttgcta atgttaaaag taaattatta
   875041 tcactagata aacacaaaaa agtactagtt tattgtcgta gcggctctcg ttcagcacat
   875101 atttctggac tattaacacg caataaattt gtaagtgtat acaacttaaa aggggggttt
   875161 caagcatgga aaagagccaa actaccaatt aaaacctaaa caatgatgaa aaaaaatatt
   875221 atttattgct cagattcttg ttttttttgc caaaaagctt accaattact tgaaaaaaaa
   875281 ggcatccatt ttaagaaaca ctacgttagg acccaagtcg actggaatga agtgaaagaa
   875341 aaaacaaata gaacaaccgt tccacaaata tttattaatg acttctatat aggaggattt
   875401 gatgacttat cagctgcaga acaatccgga aaattagatg aaattttaaa taaaacatga
   875461 gtaataacct tagtatcatt ggtgctggtg cttggggaag tgccttatcc attgctcttt
   875521 atgataactt tgatacaatt tatctacaca cccacactca agctgacatc aaaaaattaa
   875581 aatcaaaaca ttcagcatta tccataccct acccttacaa tgtaaaaatt gcttatgact
   875641 tatataaatt acaagattct aaaaacataa taattaccac acctagctat gcattttctg
   875701 aaattttaga aaaaataaag ccattcatta atcatactca taaaattgct tggggtacca
   875761 aaggttttga tacaactaaa agatgttttt tatatgaaag cttcaaacgt ttattcccaa
   875821 atcgtaatgg gtgtgttatc tctggaccaa gttttgcatt tgaagtagca ctaaataaac
   875881 ctaccgcatt agtcgtggca tctattgatg aaaataccag aaaccatttt gcaaaattaa
   875941 tacaaacaaa caccttgcgc acttatacca atgctgacat tatcggtgta gaagttggcg
   876001 gatcagttaa aaatatctta gccatagccg caggtattgc ctcgggatta aagtatggtt
   876061 ttaacactca agcagcctta atcgctagag gcttatcaga gatgtcacgt ttaggaaaaa
   876121 gtcttggtgc aaaaaattct acttttattg gcttatctgg tttaggagat ttagtactta
   876181 cttgttcaga taatctttct agaaacagaa gatttggcca agaattagtt aacaaccaca
   876241 atatcaaaaa tgcattaatc aatgtagggg gtacagttga aggacttaat acacttgatc
   876301 ttattttatc tattgccaat aaaaaacaag tagaaatgcc aatttgtgaa caagtttatc
   876361 aaattactca aggaaagata acccctgctg aagcagttaa ttatttaatg tctagagaac
   876421 aacaacagaa taacgaatga aattagatct acttaggcac ggaataccta ttggtggaca
   876481 tatttatcgt ggcaaccaaa atgatcctat tagcaaaaac ggttggcagc agatgctcaa
   876541 atctactcaa ggagaatcct gggattacat tgccagttca cccttaatac gttgtgctaa
   876601 atttgctaag tatttatcca aagaacagaa catttattgc gaaattatta ataattttaa
   876661 agaattagga tttggtgatt ggcaaggtaa aaatgttgat tctattggtc taaaattaat
   876721 taataatttt agacaagatc ctattaatca tcaaccacct aatgcagaaa acctttatga
   876781 ttttcaatca cgggttttat cttcctttga agatattaga cttcatcata ccaataaatc
   876841 agtattaatt atagcgcatg ctggtgttat tcgaataatt aaatcttact tattaaatct
   876901 acccgttgaa aaaatgttta caatagaagt ttcttgtgca tccagtgagc attttactat
   876961 ttagtatttt atttcttagt aaaactcttt taatccaaat taatttcaaa aattagaatc
   877021 ataactaaat tctcttaaaa caccatattt tagataaatt aaaaataacc aacttaacaa
   877081 aatacaaatt agtaaattaa tgaaaaaata taggtacttt gtctgcaaaa ataatattac
   877141 ttagaaagta gtcataataa gcgcaataac tgctatccta ttgctgatat ttctttacca
   877201 taaaaaaagg gggttgaagg attaccctta aattaacctt gattatatga aacagataca
   877261 aaacagtata aatatacaac aaacttaaac aatacaatta ttcaatttaa agaatacact
   877321 aattaataga caataaaacc tatacctata tttaaaagta gcttaacgct tagagaattg
   877381 ctcgctctta cgtgctttct tacgaccaac tttcttacgt tctacaattc tagcgtctcg
   877441 cgttacaaaa cctgctttac gtaacacacc ccgtaaatca ttattgtacg caataagtgc
   877501 acgagtcact cctaatctaa tcgcgccagc ttggcctgta tccccaccac ctttaactat
   877561 aatattaaaa tcaaatttat ctttcatatc agacgtatct aatggttgat taataatcat
   877621 tgaagaggtt tcacgtccaa aatattcatt cattgggcgt ttattaacta taaaaacacc
   877681 ttttccttta ctcatgtaaa cacgagctac tgatgttttt cttctacctg ttgcataata
   877741 aatttctgtt tttaccataa tatttttacc ttaaatatct aatactttag gttgttgtgc
   877801 accatgtgtg tgttcactgt ctacaaatac tttcattttt ttaaacatat ctcttcctaa
   877861 aggacctttt ggcaacatgc ccttcaccgc tttattaata attgtctctg gatttttggt
   877921 ctgtaaatct ttaaatgcta ttgattttaa gttaccaaca tatcctgtat ggtggtaata
   877981 tattttgtct tcaaatttat tacctgttac cttaattttt gaggcattga tgacaacaat
   878041 ataatcacca atatcagtat ggggtgtata ttcaggttta tgcttaccac gaagacaaga
   878101 agcaattttc gttgctaaac gacctaaggt tttaccatca gcatcaatga gtaaccagtc
   878161 tcttttgacg tcacgtgctt tagcgctaaa tgttttcata atcctatcta tattatatgt
   878221 aaaatataat ggactattat aaacattctg aactttaaat gtttacatat atttcaatac
   878281 taacataatt aatcacatca ctagattcac tttgaaaaac aactaacaat gttaatttat
   878341 ttatagtatg taataaagat aattaaaatt aaatttgtta aaattatacc taaattaggt
   878401 ataattctga tcttcatttg tcttataaat cacatgtctg aaaataaatc tgaccaaaag
   878461 tcaccatcca aatttgaacg tttaggatta tctaatacta ttttaaatgt attagattct
   878521 attggctatg aaactccttc cccaatccaa gaacaatgca taactcactt attaaataac
   878581 aaagatatta tcggtcaagc ccaaacaggc acgggaaaaa cagcagcatt cgtcctccca
   878641 ttacttgaca aaattaattt aaacattaat gcacctcaat tattaatctt agcacctacc
   878701 cgtgaacttg ccattcaagt atcagaagca gtacaaacct atgcacgagg tatgaaaggt
   878761 tttcacgtat tacctattta cggagggcaa tcttatgata ttcaactacg tcctctaaaa
   878821 cgtggcgtac atgctattgt tggaacacct ggtcgagtaa tggatcatat tgagaaaaag
   878881 actttaaaac tagataatct caaatctttc gtactagatg aagcggatga aatgcttaaa
   878941 atgggattta ttgacgatat taaatggata atgcaacgta ttccagaaca acgacaaatt
   879001 gccctttttt ctgctactat gccaaatgtt atcaaaaaaa tagctaaaca atttttaaac
   879061 caaccaaaaa ttattaagat aaaaacaaag acagaaacag caaccaccat aacccaaaaa
   879121 tactgcatgg ttggcggctt atcaaacaag ctagaagcat taactcgtat tcttgaagta
   879181 accgtatttg atgcaatgat tatttttgtt cgaaccaaaa cactcaccac agaattgaca
   879241 gaaaaactat ctgcccgggg tttttcagca gatgcaatta atggggatat tcaacaaaat
   879301 caaagggaac gtattattaa tgactacaaa cagggaaaaa ttgacatcct cattgctacc
   879361 gatattgctg ccaggggttt agatgtagaa cgcatttctc acgtagttaa ttacgatatc
   879421 ccccaagacg ctgaatctta tgtacatcgt attggcagaa caggacgtgc aggtcgaaaa
   879481 ggtgaagcaa ttttattcgt atcaaaccgt gaaagacgta tgcttaatac tattgagcat
   879541 gttactcgac aaaaaataac ccccattgaa ctacctagcg taaaaattat taatgccaaa
   879601 cgaattgaaa cattcaaaca aaatataata caaactatta acaatcaaaa cttagaaata
   879661 tttaaaaaat tagttgggga atttcaacaa gaaaatccaa aaattgaaat ctcacaaatt
   879721 tcttctgcct tggcatatat tgcacaaggc aatgaaccat tactattatc agagaaggaa
   879781 tcaaaccttg gattcaatca aacacctaaa gaaaaaataa taatctccat tagagctaaa
   879841 ccactaaaag gatttccgaa aatcccaatg tgtcgctata aaattgaagt gggtaataat
   879901 aataatgtta agacgagcaa tattttaggt gctatcgcca ataagaccaa tatggatagt
   879961 gaatatattg gatcaattca aatttttgat catttctcaa ctattgactt accggctaag
   880021 atatcaaatg aagtatttgg ggttttacaa aaaactatag tttgtggtaa gcacttaaat
   880081 attgtagaac tcactaaaaa aaataacaaa gatacaattg taggacgaac agaaaaacgt
   880141 aatcttaatc gtgggaaatt ctccaagaat aaaaacaata accaacgtga taataaaaac
   880201 tatcacagta aaaacaaaaa atatgataaa cacagcagaa aatcaaaatt atcacattaa
   880261 ggtttaaaat aaaatgaaat tgatgcgttt tttcctaatt ttaatttagt ctaaattttt
   880321 taataaaaaa ctttcttaaa gcgtatctaa ttggcaagat taactaataa ctatatatta
   880381 atctatatac tgcaattatt attatacttt gtttcaaaag aaacaaccac agcaacttat
   880441 ccgccatagt tatgacacca ttagtcatca caataaacta ggtaggggtt gaattttcca
   880501 ctttcatcac tagaatctat cttatccact cttattctct attatattat ttattacata
   880561 tctattaaca aatgtaaaag gttttattct tttagtctac tataatttgt tagaattaag
   880621 acttatattt atatatttac tgataaaaaa cattaaacac attaccaggt taaatttatt
   880681 aactaaagat cacaagctat tatacatttt cacaagaaac taaaaaataa aactttaata
   880741 acttgacaaa tacttatttt aagtaaatat tatccttaat aacaaaaata tatgctaaaa
   880801 tcagaagtgc tgtaaagaat atgctcataa aaaaattagt tttgggttgc agctactatt
   880861 tatatctatg ttgttgattg attcattgtc ggttttcgta ctctataaag gtggtctatt
   880921 ttttcggtaa tttttaactt ataggaggac acaatgtcta caacaggaaa agtcaaatgg
   880981 tttgacgcaa agaaagggtt tggttttatt gaacaagaaa gtgggggtga tgtattcgtt
   881041 cactttcgcg ctattcaagg cgatggctac aaatcattag aagaaggtca agaagtggaa
   881101 tttgacttag aagatggtga aaaaggccca caagctgtta acgtctttcc aaaataaatt
   881161 attgcttatc taaataataa gcccaattta atcactgggc ttattatcat ttcctattac
   881221 aaacaaaatt aacatatcca agaagattaa acttataata attgtataac taaattacta
   881281 acagtatcaa taattttctt attcccaata ataaatattt aatttatccc tgttttagat
   881341 ataaaagtat attttttatc taattttttt agaatatggt agaaataacc tccttcattc
   881401 atggtataaa ttctactatt tagtttttaa aactcttaaa taaatcttat gataataaac
   881461 cacttattta ctaattatat ccttatccac attctctcta actttacata tatactgtaa
   881521 cataattagg atctcatact tattaaataa tagtatttct acatttttta attaataatt
   881581 ctacagcaca agcaagtcat ctttcccttg tcaatacttt aaatgctgca cctattatat
   881641 caattactta aaaaaattac tcttgtcatt attaatttta gtagtaggcg tattatcagt
   881701 ttcaattatt tttaggtttg gatttaatat attataggtg ttacatctag ttgttagtaa
   881761 tattcctgta tatattgtta acaatttttt taaatattaa aataaccaaa gatagtaata
   881821 ataaaaaatc aatattaata atttaccttg aagatattcg gagattatat atagtagatg
   881881 atttttacta aaattgagac ataagaaatg tattcgtaaa caaccaatac actaaactag
   881941 tgtacttatg aaaacatttt attggtatga ctacgaaact tttggaattt ctccaaaaat
   882001 agatagaata tctcaatttg ctggtatcag gactgatgag aattttaata ttctagatga
   882061 acagatgttt tactgcaaac ctaccaatga ttgcttacta tctcctgaaa cctgtcttat
   882121 aactggtatt agcccgcaat tatgcgagca aaaaggaatg attgagcata aatttattaa
   882181 aaaaattcac gctcaacttt caactccaga tacctgtgtt ataggttaca attcaattcg
   882241 ttttgatgat gaattcactc gttacgcatt gtatcgtaat tttatagatc cttatacttg
   882301 gcattggaaa aatggtaata ctcgctggga tatattagac gttgtacgct tatgttatgc
   882361 acttaaaaaa gacacaagcc ttaaatgggt ttatgatgag caaaataagg taatatttaa
   882421 attagatcaa ttatcactag ctaacaacat tgaacataca tacgcacata atgctttagc
   882481 tgatgtatat gcaactattg caatagcaaa aatcattaaa aaaacacaac cacaattatt
   882541 taattatgca tttagtttaa gaaagaagaa aaccattaag gagaaaatca aactatttga
   882601 accgatgttg cacacctcaa gagtatattc tgctactctt tcttgcacac gtttatcagt
   882661 tgctcttgcc tatcattcat atcatgatcg agtctttgtg tttaaccttg atcaggatcc
   882721 ttgtatttta ctagaactta acattaaaac acttaaaact ctaatgttta ctaaaaataa
   882781 tcaatctgca ttatcaaaag aaatgaaagg actgcaaatt aaagaactaa tttttaataa
   882841 aagtccaatg tttgttccta atgtttataa actggagtca aaaattatta aacaattgaa
   882901 aattgatatg agcacttgcc ttcaacgact tgaatttatt aaaaaaaatc aggttataat
   882961 tagcaaagtt gtacaagatt tatacagaaa tgatcagcaa cgtcagccaa gttctgatgt
   883021 tgatcaagca ttatatgatg attttattaa cgacaataca gataaacata tttgcaatca
   883081 aatccaaact ttatctacta atgaattaaa aaactttcat ccaaagttta aagataatag
   883141 actctcaaaa ttactaatac acttcaaagc taggaactat ccaaatattc taactgaaaa
   883201 cgaaaaagaa gaatggttta aaactgtaca agaacgagtc caaacaggta aaaatggata
   883261 cacaaccatt gatgattatc tagcacgaat taacataata agaaaacaac acccaaatca
   883321 agaaaaatta tggaaacaac ttgaaactta tagcaagtcg ttcttttagg gtattttcat
   883381 taaatttaaa tataaggtat aatgtttagc attgagaaaa aaaataggca aagaaaaaat
   883441 gaacgccgag acacgcacaa agatatttgg aaggttgctt aaaaagatac caaatccaac
   883501 cacagaatta aactattcaa cgccatttga actattagtg gctgtaacat tgtctgccca
   883561 agcaaccgat aaaagtgtca ataaggtgac tgacaaatta tttccaattg ccaatacacc
   883621 tgaaactatt tctaaactag gagaagacac acttcgaaat acaataagaa ctattggctt
   883681 atttaactca aaagccaaac atattattca agcttgtaaa attctaattg aaaaatacaa
   883741 ctcaggtgta ccaaaaactc gtaaagaact agaagcacta cctggtgttg gtcgtaaaac
   883801 tgccaatgtt gttcttaata ctgcctttgg ccatcccact attgcagtgg atacacatat
   883861 ttatcgtgta gctaaccgca ctgctattgc gagtggtaaa actgtattag aagtagaaaa
   883921 aaaattggtt aaattcatcc ctaatgaata ccgagtacct gcacaccatt taatgattct
   883981 acatggtcgt tatacctgta aagctcgatc tccattatgc ggagagtgta ttttacttga
   884041 tctttgtgaa tacgaagaaa aaaacttata attttttaaa tattccacgc tcaagataga
   884101 acacaataac aaaaatctct taattcttaa acaagcaacg cttaactaat tagaaactca
   884161 aataacatag ataacataga taacatagat aacatagata atatttacat gtatgaccct
   884221 taactttcat cctttaaaag atagttctaa attcaccata cacttaatat taaaactaca
   884281 cataacagtt gcaaatgatc acttagttta ctaaacttca tcaaaatacc aataattatt
   884341 tttttgtttt agacttaaca atcattataa aaatttatag tctagtaata aatgatcctg
   884401 attttattaa ctttacaaat tattatagtc actgtaaatt tgattttact ttaatcttta
   884461 tatttagata aaaaagcatc tacaaaaaac aagatttaca gaaaataaac taattttgcc
   884521 aattgacaaa attactaagt aactgcaacc catcatactg tgatttctca ggatgaaatt
   884581 gtactgcaaa cagtttattt tgagcaatag cacaagtgaa atcaactcca taactagtca
   884641 aaccagcaac tacattagtg ctattttgtt ctacatagta actatgcaca ctataaaaat
   884701 atgtattatc atcaatatta tgccaaagtg gatgttctat tgtttgtttg actgtattcc
   884761 agcccatatg tggaacttta agattatttt tagaaaactt tacaatgtta ccttctacaa
   884821 tagataaacc atcagtacca ccattttccg cactaaaatc aaataaaagc tgtaaaccta
   884881 aacaaatacc caagaatggc ttctcattaa cgcaatgctt aatcacatta attaatttat
   884941 gttttactaa tacctctata caagcgccta ttgcgccttg ccctggaaaa acaatgcgat
   885001 cagcctgcat aattaaatca gcattattag ttataaccac gttgtcatta ggagcaacat
   885061 atgtaagggc tttttgcaca ctgcgtgtgt tgcccatacc ataatcaata attacaatac
   885121 tttgcacgaa tacttaaagt gatcctttgg ttgaaggaat accttcttga cgttcatctt
   885181 ctgttattgc cacacgtaat gctctgccaa atgctttaaa gatggtttca gcctgatgat
   885241 gggaattaat tcctttaaga ttatcaatat gcagtgtaac taaagcatga ttaacaaaac
   885301 cttggaaaaa ttctgaaatc aaatcaacat caaaagtacc aatcatagca cgtgtaaaac
   885361 ttacattcaa ttttagacta ggacgaccag aaaggtccaa tacaactcgc gataaagatt
   885421 catccaacgg cacataagaa taaccataac gtataaggcc ttttttatca cctactgctt
   885481 gaacaaaagc ttggcctaat gtaatgccaa tatcttcaac actgtgatga tcatcaattt
   885541 gtatatcacc atcgcattta atagttaagt ccattaatcc atgccgtgca acttgatcta
   885601 gcatgtggtc taaaaatgga acaccagtat ctatgcttgc cttacccata ccatataggt
   885661 tcaactcaac actaatgtca gtttcattgg tttttctaga tactttaatc atatttactc
   885721 tgcaaattaa aataattttt tattgtaact attgacaaaa ataatcacct caacaaaata
   885781 aagggataaa gctaaagcag ttataaaact aataattcca gtaataacca acataatcaa
   885841 aataccaata acacttgcat aaaacaacca gattactcct aagatataaa caaaataatt
   885901 aacaaaatac ttttaatagg tagtttttgt gatattaaga tttataaata ttcctcaatt
   885961 aaaatttcag caatttgtac ggtattaagc gccgcaccct tacgaatatt atcagaaact
   886021 acccacaagt ttagagcttt ttcatgggaa atatcctcac gaatacggcc tacaaacgta
   886081 tcatcatgat tagttgcctc aacaaatggt gtagcatagc caccatcttc acgcttatcc
   886141 ataaccgtca caccgtttgc ttctgataga atcttagtag ctgcagttgc agtaattttt
   886201 cttctagttt caatattaat tgcctcggaa tgaccataaa taactggcac acgaactgct
   886261 gttggattga ctaagatatt ttcatcctca aaaatttttt gagtctccca taccattttc
   886321 atttcttccc tggtataacc attgtcttga aaaacatcaa tatgtggaat gacattaaac
   886381 gcaatttgct ttggataaac cttaatatca atttcttggc catttaacaa tttaactgtt
   886441 tgatctgtta gttcagtaat tgcctccttg ccagaaccag ataccgcctg ataagtagca
   886501 acattaatac gcttaatccc tactgcatca tagattggct taagtgctac caacatttga
   886561 atggttgaac aattggggtt ggaaataata ttacgttttg tataatctac aatcgcatga
   886621 ggatttacct ctggtatcac taatgggata tccttatcac ggcgaaaata cgccgtatta
   886681 tcaatcacaa cacaccctga atcagctgca attggtgcat attttttaga aatactacct
   886741 ccagctgaaa acaaactaat ttgcacttgt gaaaaatcaa aggtgtttaa atcctgcacc
   886801 atccaacttt taccctgaca aaatactttt ttaccagtag aattagcact cgctaaagga
   886861 tataagctat taatttgaaa atttcgctgt tctaaaatag aaagaatcat ctcgcctact
   886921 acacctgttg caccaacaac agcaacatca tactttttat tcataaagtt ataatttata
   886981 agttatataa ataatattat attatataac ttataaatta tacttgagtt ttaatcaata
   887041 ttttatttgt caaaagcagg ttatttttat cctatctcac tgtccaagat aggattttat
   887101 tatttattta agtttcttta tatttttacc aaatttaaaa tacttatttt cctaaaaagg
   887161 aactatagct acgtatttaa cattaaaaat atttttgtta aagttgaatt taacactaaa
   887221 ccaactacat tacttcacaa ttttcctata taaatgttat ttgactaatt ttaataaaaa
   887281 tataattaaa attaatactt agagcagggt aaaccatcaa aacattaaca atgcataatc
   887341 acaatgccta tacaaataaa aatcaacact atgaaaatat aacaatttta atacttcttc
   887401 atgataaaac aaatattagc atcaaagaat cattatatat agcatactaa aatatatttt
   887461 aaccctacgc taaaaactaa aataaaaaaa tagactaacg ataataccat ttaaattttt
   887521 ggtaaattaa gataaatttg atattaactc ttacttttaa acttattttt catacgatat
   887581 tatcaatatc aataaattga tactgaacgt taaatttttc actcaagtgt tgacataagg
   887641 cttgtacacc ataacgctcg gtagcataat gacccgcaga tataaaagca atattattct
   887701 ctttagcaat agctggggtt tgttctgata tttctccagt aataaaacaa tcagcaccaa
   887761 tattaattgc atgtttaata tagctttggg catcaccagt acaccatgca atttttttaa
   887821 tttgttgatt aaggtctcca aatactaaag gtatacgttg tgtaatatct tgcactaatt
   887881 gagatacctc aataagtgat aatttaactt caccttgcca aaccaaagta tcgccaatag
   887941 gcgttggatt aacaatatta aggtgcattg ctagttgaat attattacca actataaggt
   888001 gagcatccaa aggaagatga taagcaaata gattaatatt tttctctagt aaaattttaa
   888061 tacgattctt tttaatgcca gtaattacta aactttcatt ttgccaaaac aatccatgat
   888121 gaacaaatag agcgtcagct ttttcatcaa ttactctttc aattaaatcc tgattgacgc
   888181 taacaccagc aatgattttt ctaatttgtt gacgcccttc aatttgcaaa ccatttggac
   888241 agtaatcatc aaatgtatct acatcaagat aatcatgaca atattcagat agagttttat
   888301 tatcaatcac ttataccttt tataatatat agaatttttc tacaatatta atgaattttt
   888361 gattttgttc ttcagtacca atcgtcacac gtaaacaatt aattaatttc ttctttacac
   888421 ttaaattttt aattaaaacg ccattttctt tcaaaaaatc aaacaaaata tttgtattag
   888481 gagctttaaa taaaataaag tttgcttgtg aaggataaac ttttaaaaca tttattttaa
   888541 caagtgcatc aaataatacc tgacgttgag caagaataac actaacattg gcattaatag
   888601 tattcttttc ttgtaaaaga aaattagcac taacttgagt taaaatattt atattataag
   888661 gtaatcgtaa tttatttaat tgatttactg tatcttgcgt agcaattaac aagcctaaac
   888721 gtaaaccagc aaaaccaatt ttagaaactg ttctaagtaa aactaaattt ggatacttgg
   888781 caatatcagt taaaaaacta tctgttgtat atgcataata ggcttcatca agcacaacca
   888841 ttgccttagt tgaactaata atatgctcaa taatttctcg attaaacata ttgcctgttg
   888901 gattatttgg ataagcaata aaaattaatt taggattata agtttttatt gccttttgca
   888961 tagtatcatc gtcaatctca aaatcatctg ttaataaaac actctgataa ttaagacgtg
   889021 taaattttgt aatcattcca tacatcacaa aacttggttc aacacttaaa acagtatctc
   889081 cggtattaca tgccaaagct aataattgga ttaattcatc tgatccatta cctagtaata
   889141 cgccaaattc tttaggaata ttcatcaata atctaagtgt ttgattcaat ttatctgaac
   889201 tagggcttgg atagcgatta agctgtgcat caactaaata ggttaaatat tgatctgtta
   889261 attcgtcaga taaagaaaat ggagattcca tagcatccat ttttaccata tcagcagaaa
   889321 ttggcacatg ataggcatta atcatcttaa tatcagatct caaccaactg ttaataaagc
   889381 tcataatggt ttttgtctat ttggatgcaa ttgcatttta ccaatactct tagcatttaa
   889441 caaagtttga tatgtatagt ctaatgctcg cttgcttgca atctcaatat ccaaacccaa
   889501 tgcaattaat gcactcattg cacttgaaag tgtacaacca gaaccatgat aactacctgg
   889561 taacttttga taagagaaac tttgaatgag tgttccgtag tgatacaaac aatgttcaat
   889621 cacatcatca gatgaatcag tttttgtaag taaaatccaa ttataagaga gtttcttaat
   889681 agctttttgc tcatcttgtt cgtccgccaa aatttgtaat tctgttaaat taggtgtaat
   889741 aacttttacc attggtaata attgatgttt taaagaatca attaaaacac tatctaaaaa
   889801 atcaaaatca ctactagatt tcacaattgg gtcaagaact atgattttat ttttaaccaa
   889861 cttagtaatg gttctaattt gctgaattga agataacaaa ccgatcttca ccacttcaaa
   889921 atcaacatca gcttgtaagc actcaaattg ttgaataata aatttgcaat ccacctcaac
   889981 taaattctca actgacgctg tattttgtac ggtaaggttg gtaataataa ccagtggtgt
   890041 tacgccaaat tgattaatac tttcaatatc agcaactaat cctgcacctc cacaaggatc
   890101 aagtcctgat aaaactaaga ctgtattatt caagcttgct ttcttttttg attaaaaaat
   890161 ctaccacttt aaacatatca atatgcgaac ctgcatatgt tgcatcggtc aagtatttac
   890221 cattaataat aatagctggt acacctgtaa tcttatattt aagtgtattc aacttagatc
   890281 tatttacttt aattttcaca ttaaaagagt tgaatgctgt ttctatctta tttttattaa
   890341 caccaaaact tgccacccaa ttaacaaaac tctctttaga attaaagcgt ttattattta
   890401 catggattac atcaaataac tcctcatgca atttttcaac taggtctaac tcttctaaca
   890461 caaaataaaa aattgcacca tttaaccagc gctcagaaaa aatagctgtt tggcgcacaa
   890521 attcaacatt actaggcttg gttttaagcc acctatttat aagtggttca agattataac
   890581 aatgtaggca atagtaccaa aataactcac gcacttcaat tttatcaccc gtaatagttt
   890641 taacaggctt attaagcact atataatcta tgccagcttc ataatctttc gaaaatacaa
   890701 agctagaaaa tgcaataagt aaaatagata gtatcttttt catagttatt ccgtatttaa
   890761 gatgtcaata ttatacgatt ttaatccact catggttgcc cgtaactgag tataagtttg
   890821 atgttgttgt ggatgaacca gatttgggtt taactctgct aatggcataa gcacaaaatt
   890881 atatttcaga atatcatctc ttggtaagtt gtaattttga tcaataactg aatcatataa
   890941 agttaaatca agatcaattg aacgggatga aaattttgac gcctctctat ccctaccaag
   891001 attttcttca atgtcatgta atatattaac cacctcagca attattaaat tagtagtcgc
   891061 attaatacca acattataaa aattatcacc tttaaaacca aatgctctag attcataaac
   891121 cttagaaaaa accgtatttt caaacattac tttaatagca taaatcgcct tagatagatt
   891181 ttccctacga ttccggtttg atccaatatt aatatggata ttagccatta ctacgttcaa
   891241 tgacaatacc tactccttgc gctcccgtca acacttcacc tttattcaag gtaagtttta
   891301 tccaagtaac tttaaattct ttcaatacaa tttgagtaat tctttcagct aaagtttcaa
   891361 ccaattgaaa ttcactacgc tgaacaaaat caattaatcg ctttgatact gccttgtaat
   891421 ccaaagcttg attaatatga tcggttttac tagcagcttt aatattagct gacatttcaa
   891481 tatccaacac aatatcttga cgaatttttc gctcccaatc ataaatacca ataaccgtat
   891541 caatttttaa tccttgtata aatataatat ccattataaa attttgagca gctaaaatta
   891601 ctaatccaat taaaccaaaa gaaactatta tgttacctga gttattcttt actattatta
   891661 tccttagtta tctaattggt tcaatttcaa cagccattat tatctgtaaa atacttaatc
   891721 tacctgaccc tagaactcaa gggtcaaaca atccaggtgc tacaaatata cttaggatag
   891781 gtgggaaaaa agcagctatc atcacactcg ttggagatgg acttaagggt atgattccag
   891841 tattaattgc ccattactta gacttagata cacttaatat tacttggatt atcttcgcag
   891901 catttttagg tcatgtatac ccaatcttct ttagctttaa aggcggaaaa ggagttgcaa
   891961 ctttcctagg cgctttactt gcccttagtt atcctactgg gctgagcttt ataatcactt
   892021 ggatttttgt ggcaaaagta ctaaaaatct catcattatc agcactagta gctaccgcac
   892081 tcacaccagt ttatttctat ctaattacta ataatttaat tgctacttat gtcattatct
   892141 caatatgtat atggattttt tacacccatc aaagtaatat taagagacta ttcaataacc
   892201 aagaaaataa aatcaattag cacttaaaat ctcaacattt acccattaaa acaaaaacca
   892261 tatcttaatt atataatgtt acaataatat aattatttaa atttaaacac cacaatatta
   892321 tgttaataag gaaaaaattt agtaaaaaag atgctaaaaa caagataaaa aaattacaaa
   892381 ataacaaata tgttatgcat aaaaataatg tcatgtctgg caatgcattg ttaagcttat
   892441 cagaaatagc aggagattac ccttatgcta aaaaaatgca cgttgaagaa tacgagaatg
   892501 aaaaatattt attacaaaca gagttactaa aagcacaaga ttggattaaa aattacaata
   892561 aaaaaattat cttattattc gaaggccgtg atgcagctgg aaagggcggt acaattaagc
   892621 gttttatgga acaccttaat cctcgtgctg cacgtgtgat tgccttagaa aaaccatcaa
   892681 gagtagaact aggacaatgg tattttcaac gctacattaa acattttcct accaatggag
   892741 agatggtact atttgaccga tcttggtata atagagctgg tgtagaacgt gttatgggct
   892801 tttgtaaaaa ctcagaatat ctagaattta tgcggcaagc gcctttactg gaacgtatgc
   892861 tagttaatga tggctttatg ctttctaagt actggttttc tgttagtcat caagagcaat
   892921 taaggcgctt tcatctacgt aaaaacgacc ccttaaaaag gtggaagtta agtgaaattg
   892981 atttacaatc attaacaaaa tgggagcaat ataccaaggc tagaaaagat atgttttttt
   893041 acaccaatac cgctgattca tcttggattg ttgtaaaatc agatgataaa aaacgtgcaa
   893101 gaattaattg tattaggcat tttctttact atctaaatta tcctaataaa gatactaaaa
   893161 tagtttttaa gcctgattca aaaattattg gaagtgtgag taatttatat aaaaataagg
   893221 aggatatttg atatcaaata aaaaacaaca attaaaagat gctatacaaa ttgcaagaaa
   893281 agcagaaatt gaagccttaa ttgcaactga gaaagctcaa aaatctgtta ataaaatagt
   893341 aaaattaaga aaagaattag atgtacagta taaaaaatta gccaaaaaaa tcaaagaaaa
   893401 taaaaaaaac aacgacaaaa aaatagagta tttttctaaa aagaaagtaa aaaaagcaaa
   893461 gaaaaaaaaa tctttaaaat gatttcagtt cttaactagt ttatcataat aaccattata
   893521 tatagtgaaa taggactaca tttttagtaa ttattcttct aaaaaataat tatataatat
   893581 attaagtttt aatattcaca tttcttttta atagacaaaa tgcaaatatt gccaatacaa
   893641 taattatact caataagact aaaattgata cccaaaactc agaagtgcta acacctaaaa
   893701 atcccaatct aaaactatca accatataat aaataggatt aaatttagat atattttgcc
   893761 aaaactgggg tagtatttct acattataaa atataccgcc aagataagtc ataggcataa
   893821 gaacaaaagt aggaacaata gagatatcat caaacgattg ggcaaaaata gcgttaataa
   893881 atcctgctaa tgagaataaa attgaggtaa ataaaaaaat aataagtaca attagcatat
   893941 tatttatttc aaaatcaata aaaaaactca tagcaataga aacccccaac ccaactgcaa
   894001 agcctcgcga tacaccacca gatacataac ctaataaaat aacccaataa gacacaggtg
   894061 ctactaataa ttcttcaatg ctatgattaa attttgctaa aaaaaacgat gttactgtat
   894121 tagtataaga gttagtaata accgtcatta gaatcacccc aggaattata taatgcaaat
   894181 aatccacacc ttgcatatca ccaatacgct tgcccatcaa accaccaaaa attaataaat
   894241 atagtgatgt agtgataatg ggtggaaaaa tagtttgcac ccaaatgcga gaaaatctta
   894301 aaatttcctt aataacaata gttttataag aaatccacat cattcctcct tgttagttaa
   894361 gtataaaaat aaagtttcta aacgattttg agcgctatga acatagtcca cactaacacc
   894421 ttgtgtatct aaatcatgta acacactggt aatgctaata tctgagttca atacaacttg
   894481 taatgaatgg tcatctaaac gttcacattt aaacctatca cttgttatag tctgaggcaa
   894541 ttgagataag ctttccaaaa tcagcacttg ttggtcaact tgtgacaata atgccttcat
   894601 actagtttgc ttaatcactt tgccttcatt tagaatagca acattacgac aaagtaactc
   894661 agcctctcca agataatgtg tagttaaaat aatagtcata ccttggcgat taagtttact
   894721 caaaaaacgc catattgaat ggcgtatttt aacatcaaca cctgcggtag gttcatcaag
   894781 aattaatatc ttaggttgat gaatgagcgc ccttgctaac attaaacgtc tcttcatacc
   894841 acctgataat gatttagcca tatcagagcg tttttcccaa agatctacct ctttgagtaa
   894901 aaactcagct tgaattttag cttttgactt agcaatgccg taataacctg cttgattaat
   894961 caaaatttcc tcaataggtt caaaaggatt aaaattaaat tcttgcggca ttaatccaat
   895021 taattttttc acctgattaa catggttact ttgattaaaa cctaatacct taatactacc
   895081 tgaagtttta ttgagtaacc cgcaaataat accaataact gttgtctttc ctgcgccatt
   895141 acttcctaat aatgcataaa aatcaccatg atcaacacaa agatcaatac cttttaatgc
   895201 ttctaattga ttagaataag tcttttttaa acctttaatg agtaatgcag tagacataat
   895261 gagtttagaa taaaaatcaa aacattttaa catttatccc cttttattag ctatttttgc
   895321 gataattacc cactttaaat tattttccaa aacatacaaa acttatgatg aacataaaaa
   895381 atatagtact acctgatatt ggtgattttt atgaagttaa aataattgag attttagtaa
   895441 atgttggaga caagataaac actaatgata gtatagtaac attggaaaaa gacaaatctt
   895501 ctatgaaaat tccaagccct tatacaggta ttattacgaa aattgaagtt aatattggta
   895561 acaaaattaa acagaatgat atcatcttga gcattgaaag tgaatatagt gagattcaaa
   895621 ataccaacaa aaatatcaaa aatgaatatc aaaaaacaga aattataccc gttgttgtgc
   895681 ctaatattgg tgattttgat gaaattgagg tcattgaaat cctagtcagt gtaggagatg
   895741 aactatctgt ggaagacagt ataatcacct tagaaagtga taaagcttca atggaaatcc
   895801 caacaccagt tgcaggcaag gttattaata ttaatgttgc actaggtgat aaaatttctc
   895861 taggtacgtt aattcttaat attaaaagta tagctgaaga aacacctact gaaattaaaa
   895921 tacaaagctc aacaccgata ccaataccac cgaaccctag tacactaacg cccataacaa
   895981 ataacattaa tcaaatagtt tcagaaccaa tcagaggcaa ctcacacgct tcaccttcta
   896041 ttcgtaaact agctagagag ttaggtgtta atttatcata tataactggc acaggaagaa
   896101 aaggcagaat tttagatact gatcttaaaa gccacgttaa acaaataatc acttctaaca
   896161 actttaacag cgtccttcct aaaccaccaa taattgattt ttctaaattt ggcaacactg
   896221 aaacaataaa actatccaga ataaataaat tatcaggtaa acatttaact acctgctggt
   896281 taagcattcc ccacgttacc caatttgacg aagttaacat taatcaaatg gaagcatacc
   896341 gacaagaaca aaaagctaac ggcattaaac tcactcctct agtttttatt atgaaagcat
   896401 tagttcgaac gttgaaaaat catctgcgtt ttaatgcatc acttgatgag tcaggtgaaa
   896461 acttgattat taaaaaatat ttcaacttag gaattgcaat ggacacacca aaaggcttaa
   896521 ttgtgccagt tattcgtgat gttgaaaaaa aatctttaac tgatttggct aaagaacttt
   896581 ttgaaacttc aaaaaacgca cgagaaaaca agttaaaacc agcagatatg caaggttcag
   896641 gtttaactat ttccagctta ggtggtattg gtggtacaca atttacccct attgttaatg
   896701 cgccagaggt agctatttta ggcatatcac gttcatattt caaacccact tgggatggtg
   896761 aaaatttcat cccaacttta acattaccac tagcattgtc ctatgaccat cgcgtgattg
   896821 atggtgcaca aggtggacga ttcatggcag aattaaatac aacattaaga gaggcaaatt
   896881 atgattaaga ctcaaattgt tattataggc tctggtcctg ggggttatac agctgccttt
   896941 cgtctggcag atttaggtaa acaagttact ctaattgaac gttataacgc tttaggtggt
   897001 gtatgcttaa atgtcggctg tattccttct aaagcacttc ttcatacagc ccaaatcatc
   897061 aatgaagcaa aagatgcctc acatgtaggt gttaccttta atgaaccatt aattagcatt
   897121 aatggtatac gtacaaataa agacaacatc gtaaccaaac taacaaatgg tataaaaact
   897181 ttagcaaaag caagaaaaat taatgttata acaggttatg gaagatttat ctcagctaat
   897241 caaattacaa tcgaaaatag cgatgatatt attgaatttg aacaatgtat tattgctaca
   897301 ggttcgcaag ttaccaaaat ccccaccctt ccatttgatg atgctcgtgt aatgagttca
   897361 acagatgcac taaacttatc caatatacca aaacgtttgt tagtggtagg tgggggtatt
   897421 attggcttag aaatggcaac agtttataac gcgcttggta gcgaaattac tgtggttgaa
   897481 ctttctgacc aactaattac tagtgccgac aaagacatta tcaatccact acttagacgc
   897541 attaaaaaac aatatgctaa catcttttta aacaccaaaa taaccaaaat tgaggcatta
   897601 aaagaaggta ttaaagtcag atttgaggga aaaaacaccc caaaattcga cacctttgat
   897661 aaaatactag tcgctattgg tcgcacccct aatggaagat tgatcgattg tgaaaaagct
   897721 ggtgttgaaa taaatgattg gggctttatt cctgtcaata aacaaatgaa aaccaatgtt
   897781 aataacatct acgccattgg cgacattatt ggtcaaccta tgcttgccca taaagccata
   897841 cacgaagcta aaattgcagc agaagtcatt tgcggataca aatcaggttt taatgccctt
   897901 accatcccat ctattgccta tactgatcca gaaattgctt ggacaggaaa aacagaaaaa
   897961 gaactcaaag ctgaaggaat ctcttatgaa aaaggtttat ttccttggac aaattcaggt
   898021 cgtagtttaa gtattggtag atctgaaggc attactaaag ggttgttcga tacaaaaata
   898081 ggcaaaattt taggaatggg tatttgcggt accaatgcaa gtgagttgat tgctgaagca
   898141 acactagcta ttgaaatggg ttgtgatatg gatgatattg cactaactat ccacgcccac
   898201 ccaaccttaa gtgaaactac cgcctttgca actgaaatgg cacaaggtac aattacagat
   898261 ttattatcat caaaaaagaa aaaataggga gagattatat gaatataaaa caagcaagaa
   898321 aaaatgtcat tgaacaacaa atacgccctt ggggcggctt gaattatatt gctaataatg
   898381 cacttaaaga tacaccaaga gaagattttg taccagagaa atataaaaat cttacatttg
   898441 cagatattga aattccactt actagtaaag caaaaatgct ttttccaaag attgaaggac
   898501 gattattaaa tgcacttaat attaaaaaac atgaaactgt actagagata ggaacaggta
   898561 gtggttattt aacagctgtt ttatcaaaat tatgcaaatc tgtaaccagt attgaaattg
   898621 atgaaaatct tagtcataat gccaaaaaaa gaattgatac attgggcatt gataatgtta
   898681 ctttagaagt ggtagatgct tctaagaact ggaagtataa tgatttcttt aatgtagtaa
   898741 ttattagtag ttcagtacct aaaattacag gttattactt tcatttatta aatataggtg
   898801 gtagaatttt tgtgattgaa ggtactaaaa acattatgag tgcaaaactt attactcgaa
   898861 ttagtaagaa taaatgggat acaaaatcct tatttgaaac acaattagac gccatgcgag
   898921 gattagaatc atcaaataat tttgaatttt aattatgaac ttatttttcg attttatcct
   898981 aaaaaaagcc tcattagggc ttacactgtt gttactaatt gctatatttt ttatagctca
   899041 aatctctgat tttcaactag atgcatctgc agactcttta gtactggaag gtgatgaaaa
   899101 cctgcgttat taccaaaaca ttaagaaaaa ttatgggtct gatgattatt taatcatctc
   899161 ttatcaggtt aaagacagtt tgattacacc taaacaactt gatcatctta gaaaatttaa
   899221 acaagattta actaaaatta accagatcag gtcagtaacg actattctag atgtaccact
   899281 ttttagatcc cctcccttat ctttagcaga actagctagt gaaaacatca gcattgataa
   899341 tgataatgct aacttagctt tagctaataa tgaattcaaa aattcacctt tatatgctaa
   899401 caatttagtc agtaaagatg gaaaaacaac tgctattcta gtgaaactaa aaaataatca
   899461 aaagttcaaa gaattacgtg aaaatcttga caaaatgcgc acccaaagag ctaataataa
   899521 attatcaaat gaccaacaat taaaacttaa aattatcgaa aagcaagttt taaagaatat
   899581 cactacccag aataaaatac aagcacaaac aattgcccaa attcgaacta ctattaacca
   899641 atattcaaac aaggctcatt tattcttagg tggtttacct atgataacta ctgatattgt
   899701 gacctatatt agcaatgatt tgatcatatt tagtttagca gttattgggt tgatgagttt
   899761 aattttaaca attattttca aaagtgttcg atgggtcatt atcccaattg gcattagtat
   899821 tttcagttcg tttatcatga caggtatttt agcttattta ggttggaaaa ttaccgttat
   899881 ttcatctaat tttttctcat tattactagt tatgacactt tctatagtta ttcaccttat
   899941 agttagatat agagaaattt cccagcttaa tccaaatatc aactcacatc aactaattaa
   900001 agacaccttg tcacaaatgt ttaagccttg tttttttaca actttaacca catttgtagc
   900061 ttttagttct ttacttatta gtggtatcag acctgtgatt aattttggct ggataatgtc
   900121 aattggcgtg attattgctc ttgtgttatc gtttttagct tttccgatga tcatgagttt
   900181 gttaccaaaa gcaaaaatta caaaacagaa aaccgaacta agagctacca ctttattagc
   900241 caaatttgta gaaaaatttg gtaatcattt attagtaata ttagtaatat tactaatagg
   900301 ttctggattt ggaattagca aacttagtgt tgaaaatcgt tttattaatt attttaaaca
   900361 aaacacagag atcaaccaag ggctaacttt gattgataaa gaactaggtg gcactattcc
   900421 actagaaatt atttttgaca atttagcaga agactactgg tttgacgagg atttacgtaa
   900481 tgagatacac gatgttcatc aatatcttaa ttctttagat gaaactggca aagtattatc
   900541 aattgacact ttaatgcaga ttctaaccca agctaatgat ggtaaaacac ctaatggatt
   900601 tctcttaaac attattcact cacaattacc tgaacgtgct aaagtacaag tgttatatcc
   900661 ttatttatct gaaaacagtg gacaactaag aatggttatc cgtattagag aaactgaaaa
   900721 agaattaaaa cgtggaaagt taattgatca aatacaacat catatttcta ctgaacttgg
   900781 atttaaacag aatagttttc atttaagcgg tatgctaatt ttatacaaca acatgttaca
   900841 aagtttattt gactcgcaaa taaaaacaat tactgtggta tttgtaatga tttttatcat
   900901 gtttttattt attttcaaat caattagttt atccataatt gcattaattc caaacacttt
   900961 accatcactt tttatccttg gtattatggg attattaaat atcccactag acttaatgac
   901021 tatcactatt tcaacaattg ctattggtat tggcgttgat aacgccattc actatatcca
   901081 tcgttttcag catgaattta gaaaagacaa cgattatata gcaactatgt atcgctcaca
   901141 tactagcatt ggattagcta tgttttatac ctcaattaca gttacaatag gctttttaat
   901201 tttagcttta tctaatttta taccaagtat ttattttggt gtatttacag ctattgcaat
   901261 gcttagtgca ctacttgcca atttaaccct actacctaaa ttaatactaa tgataaaacc
   901321 aaaaattaat atataaatcc acgccaatga attaaaaaag attatgccaa taatattcat
   901381 ttatcgttaa tacccatgac aaaacaacat cattttgacg ttctaattat tggtacaggt
   901441 agtgcaggat taatgagtgc attacaatta tcagataatt taagtattgc actaattgcc
   901501 aaagataaaa tattagaagg cagttcatac tatgcacaag gcggtatatc tgctgtacta
   901561 gacataaatg acaactttac tactcatata caagatacct tgttaactgc agcaggctta
   901621 ggtgatgaaa ctgccattcg ctttatggtt gaaaatgcac ccaaagccat tacctcatta
   901681 gaacattccg gagttaaatt taccaaaaat aaagataaag aagattatca tctaaccact
   901741 gaaggtggtc atagccatag aagagtagca catgttgctg ataaaacagg acaatcaatc
   901801 caaactaatt tgcttaaaaa cgttaaagaa aaaagcaata taacactttt tgaaaactat
   901861 attgccattg atttattaat caaatcctac gactgctatg gtgcttatgt tttaaacaaa
   901921 aatactaacc aagttgaaag ttttatctct cataaaacta ttattgccac aggcggagca
   901981 tcaaaaactt atctttatac ctccaacccg gatacatcaa caggtgatgg tattgccatg
   902041 gcttatcgag caaaatgtat tattactaat atggaattta cccaattcca tcctacttgc
   902101 ctttaccatc cacatgcaaa atctttttta attaccgagg cgcttcgtgg cgaaggtggt
   902161 aagctaattt tacaaaatgg tgaagctttt atgcataaat ttgacaatcg agaggagctt
   902221 gcaccacgtg atattgttgc ccgtgcaatt gatgtacaaa taaaaaccca tgggtttgaa
   902281 tgtgtttatt tagacatttc atttaaaaat aaaagctgga ttaagcaaca ttttccaaca
   902341 atttacaaaa aatgtaaatc acttggtatt gatatttcta aaaatgctat ccctgttgta
   902401 cctgcagcac attatacatg tggaggcgta caaaccaatc ttgacggaca aactaatata
   902461 gacaatctat acgccattgg agaagttgca cacactggtg tacatggtgc taatcgtatg
   902521 gcaagtaatt ctttattaga atgtgtagta tttgctaaat cttgtgctaa ttatataaat
   902581 caacaatcaa caacattaac attaacatat aaacaattta gtcagtggga cgcttccaaa
   902641 gcagcacctt caaaagaaaa agtagtcgta tcacatttat gggatgaaat tcgccgtatt
   902701 atgtggaatt ttgttggtat tgtacgttct aacaaacgct taaaatatgc acagtatcgt
   902761 ctgaatcaga ttcaagcaga agtgaacgat tactacaaac tttatttaat atctagtaac
   902821 ttaattgaac taagaaacct tattcaaacc gcacaactaa ttgtgcaatc tgcaattttt
   902881 agaacagaaa gtagaggatt gcattacaat gaagatcatc cacaacaatc aaatcatccc
   902941 attaatacta taattaaaaa atcatgattc tacccatctt aagctaccct gataaacgct
   903001 taagaattaa agccaaaaat gtgaatatag ttaataaaac catacaaact ttaatcaaaa
   903061 atatgtttga aactatgtat gctagaaacg gtatcggatt agctgctacc caagttaacc
   903121 aacatctaca aatagtagta attgatgtgc caaactctca atttttattt aaaaatcgaa
   903181 aaaataactc acaaaagtta ctacaaaaac aacacccttt atgttttatc aacccagaaa
   903241 ttaaagaaaa atatggacaa gaaaaacaca ccgaaggttg tctatctgtg tcagattttc
   903301 aagcagagat tcaacgtgct aaccatatta aagttaaagc actcaacgaa aaaggtgaga
   903361 tatttatcct gcaagcaaca ggactacttg ctatttgtat ccagcatgaa atagatcatt
   903421 taaagggtat tttatttgtt gattacttat ccaaactcaa gcaaaaacga ctcctagaaa
   903481 gaataaaaaa gatgactaaa gtatagaaaa ctaatactaa tcaaaattaa cacctataaa
   903541 ctcaatttcc aaatattact tatagcctat aactatacca tttagactat tatataatcc
   903601 agaagatatg gcattaacaa cctaagaaaa atagtattaa aaaataattt actcaaaata
   903661 aagggataat aacaacaatt agtattcgaa taatcagata tgaaacttta aagttgtaaa
   903721 tatcttataa gaactattaa atttaatata taaatgatag gttaaatctg taaaaaatag
   903781 aaggttatag aaaacacatc ttttagtgta ttacgtactt taacaaaaaa tatattcaac
   903841 aatcttggta aaacattaac caaattagta ctcaaaaata attcaaccta cttgaaaaac
   903901 acctgaaata attatgatct caactgattt actagtatgt attaatacaa aacttaaaca
   903961 ttactttaag caattatatg atgaacaaac aagcagtata cataaaataa gcattaataa
   904021 tgtaaagtct gttgtaatta atttatattt acttgactta gttaaccata atcaaagcga
   904081 agttttaaaa attttagaca ttaatcttgt cacattaaaa aaattcaacg atacaaacta
   904141 taacacttta taataatttt aattagcgta aaaaatatta aagaaataaa tgtctataca
   904201 acgagcttta atcagtgttt ctaataaaaa tggagttatt gattttgccc aattcttggt
   904261 agataataat atcgatatta tttccacaga tggtacagca aaacttttaa tagaaaataa
   904321 tattccagta attgaggtct cagattacac aaggtttcct gaaataatgg caggtcgggt
   904381 taaaactctt aaccctaaaa ttcatggcgg tattttagcg cgtcgtggaa ttgatgagga
   904441 tataatggca caaaacaaca ttaagccaat tgacttagtt atagttaacc tatatccatt
   904501 ccaagcaacg attgccaaaa ctgattgtac attggaagat gcaattgaaa atattgatat
   904561 tggcggctca gcaatgctta gatcaagtgc caaaaattat acatctgtta cagttatagt
   904621 aaataacaca gactatcaaa aagttatgga tgaaataagc gaattaggca atactacact
   904681 cgaaactaga gctatgctag cccttaaaac atttgaacat actgccatgt atgatggagc
   904741 aattgctaat tatttaggca aaaataaaaa tggcttctct aacactataa atctacaatt
   904801 taataaagca caatcaatac gttatggtga aaacccacat caaaaagctg ctttctatgt
   904861 tgaaagcaac ttatcagaat cttgtttggc atcttctatt caatgtcaag gtaaagaaat
   904921 gtcatataat aatatggctg atgctgatgc tgcccttgaa tgtgtacgta gttttaacaa
   904981 gccctgttgt gtgattgtta agcatgccaa cccttgtggc atagctattc gtaacaatat
   905041 taataatgcc tatttagatg cttttaaaac tgacccaacc tctgcatttg gcggcattat
   905101 tgcctttaac agagtgctag ataaaaacac agctcaaaat attattgata aacaatttgt
   905161 agaagtcatt attgcaccaa gtgtacaaac acaagctaaa caaatactat ctaccaaaca
   905221 aaatatacgc gtactagaat gtggtaattt aaacacagca aaaccttctt tagattatag
   905281 acgtgtaact ggtggtttat tggtacaaga taaagaccta ggcattatca cagaagatga
   905341 tataaaatgt gtcagtgatt taacacctac caaagaccaa atagaagatt tattatttgc
   905401 ttggaaagtt gctaaagtcg ttaaatcaaa cgctattgtt tacgctaaaa ataaaatgac
   905461 catcgggatt ggtgcaggtc aaatgtccag ggtctattct gctagaatag ctggtatgaa
   905521 agctactgac gcagatttta ttattgatag ctgcgtaatg gcctctgatg cttttttccc
   905581 atttcgtgat ggtattgact cagtagcaca agctggcatt aaagccatca ttcaaccagg
   905641 tgggtcgata cgtgataaac aggttattaa ggcagctaat gaacacggta tcacaatggt
   905701 atttacaggt atgcgtcatt ttaaacatta attttaaata tatattatta aaatttatcc
   905761 acacaaatta ataaggattt tttaggtttt ttcttataat taaaaaatca atattttaag
   905821 ataatataac ttaaaaaagt aaacctaata agttctttag attgctctat aaaattattt
   905881 gatgaagttg tcatattata ctgaatttag cgctaaatac taatcattat taatccaaat
   905941 cttaaaacaa tcataacttt aactttagat ttaactgatc tttattatta ataacaaact
   906001 taatatcaag aacttaaaag tagtattgga gagttatgaa tacttaacac cttaattcat
   906061 tagaaatata ctaatgggtg atttatttca aaataaaaat aatcaattta atctattggt
   906121 aattcttaaa caacaaatat tttatctatg aaagaattct cactttaaac gaccttcctt
   906181 ttaacttatc ataccttatc ttttttaatg ccgttttaac aaaatttgaa ttaactgcaa
   906241 cataagacca ctgactaagc acattaattt ttccaatctg attaaaagta atctcttttt
   906301 ttttgccagt taatccacct acaatatcac ctggacgtaa tttgtgtttc ttaccaccgt
   906361 ctatcttcaa ggttatcatg gatggttttt taatggggtt atttaaataa tgcttacttg
   906421 gtaatgaatc tagaataata tcatccccag tacctaattt taatgtatca agtttatagg
   906481 tttctctatt actatacaaa gtacaagcaa ttccaaaatg ccctgctctg ccagtacgtc
   906541 caatacgatg tatatgaact tgatcatcat gggcaatgtc aaaattaatc accatatcaa
   906601 gagagtcaat gtctaacccc cgggctgcca catcagttgc cacgagaata gacacacttt
   906661 tattagaaaa tctaatcaac gcctgatctc gttctctttg atcaagatcg ccatgaatgg
   906721 ctaatgcata gaatccataa taaaccaact cattagcaac tttctgtgca tcccgcttag
   906781 tattacaaaa caccaaacta gattcaggtt tatattttgc cagcaaaagt ctcaaagcca
   906841 tcatacgttc attatctgta ttgattttat agaaatactg cttaatagtt gatctttcat
   906901 ttattaatgg taccttaacc ataataggag acctcatcac gcgctgcgtg atattggtaa
   906961 tagtatctaa acaagtcgca ctgaataata aggtttgtcg attagtaggc attgtttcaa
   907021 taatattgtc aacagattct tgaaaaccca tatctagcat acgatctgct tcatcaagaa
   907081 ctaatgtatt aatataactc aatttaagcg taccttttcg caaatgttct tcaatacgcc
   907141 caggcgtacc caccacaaca tgcacaccat gtcttaatga atcaatttgc agcccaaaag
   907201 acataccacc acacaacacc acaaccttaa tattattaat aactctagct aatttttgaa
   907261 tttcaaccgc tacttgatta gccaactcac gagttggaca taaaacaatg gattgcaatt
   907321 taaacaattt aacatccagt ttttgtaaca aacctaagcc aaatgccact gtcttacctg
   907381 aacctgtctt accttgacca atcacatctt taccagatag aataactggt agactcaact
   907441 tctgaatagg tgtcattaaa tcataaccta aaatcgttaa attttttaat aaatttggat
   907501 gtaacttcaa tgaagaaaaa tcagtcgcgt tcaaaataat aaaagttaat taatatagaa
   907561 tagattttac gccaatcttt tatattaaac cccttatacc aataatttaa aaacaaggct
   907621 tatttacttt aaatactctc taaaaatata ttcttttata aaaaattcaa ataattatta
   907681 tatattatat ttatagaaaa caccaaaata accttcaaac tttcttcttg aatcttatga
   907741 ttcaattttc ttgtaacata ataccgatga aaaaagttat aattattatt atgaaagcat
   907801 taagactaac actcagacaa aaaagacaca ctattaatca caacaatcga aaaaaatttg
   907861 cccaattctt attatttcaa acacaaaaat taaccacttt taaacgtgaa gaaaaaattg
   907921 ctatttatct gccaaatgat ggtgaaattg acactaaata tattgctaac ttcttaaaaa
   907981 gacaaaattt tagtatatat ttaccaaaac taattggtaa aaaacttaaa tttgcaaaag
   908041 ttaataagtt tttcaaaaag aatatatttg gcattaaaga gcctatttac actaaaatct
   908101 taaacaccaa acaaatgaat attatcttcg tgccactagt tggttttgat aaaaataaga
   908161 accgaattgg catgggtagt ggtttttatg accacacact tgctttcaaa aaataccaac
   908221 aaaattataa aaatccaaaa ctttatggtt tagcatttga ttgccaaaaa gtagataagc
   908281 ttaacacaaa accttgggat gtaccacttg acgcaatcat aacaccaaca aaaatttaca
   908341 ataaataaaa atataaaata ttttaatttg tcctatcagg gttatacctg cgcctgaatt
   908401 gatttcagtt tatttctata aaaataaaca tactaaatca atagtactgt tcttttataa
   908461 atattaacct atcattgaaa catcaacact aattctcctc taatcttcta agattatttt
   908521 aaagttgcta taaagattca aaatatcaat tatttattag acctgtaaga cttattgaat
   908581 gtttaagtga gtctttcatt ttaaaaaaat aattgatatt tttataccct ctataccctc
   908641 tataccctat aaacaataag cattagtaag agatatagtg taagtagcga attttttaaa
   908701 aggactatac taaatattaa atagtttatt tcctgaagct tgtttttgaa agtaagattt
   908761 taaagtctta ctttcattaa ttaaattcat accaaaacca cgcaaccatc taagtggttc
   908821 gttattctct ttataaatcc aattgagccc agtcatagtt tttgccataa gttcattgtt
   908881 taatcttctg gatctagcat atttttttaa tactaaataa tcatctaaag atttatgatt
   908941 agcttgtatt tgttgtgata attcgataac atcagaaaaa cctaaattaa ctccttgacc
   909001 tccaagagga tgaatattat gcgcagcatc accaattaat actaaattac gttttatata
   909061 atcttgtgca ctacgctcaa tgagcgtaaa ggatttaata tcactaacaa ctttaaatcg
   909121 actaaattta tattcaacac ttttagaaag tctatcggca aactgcttaa ctgaaagttg
   909181 tataagctcg tcagctaaat tattttctgc tgaccaaaca atggatgctt gtttatcact
   909241 taaaggaagt aaagcaataa tactgtctga taagaaacgt tgccaaattg tattctgaaa
   909301 actttgtaag gattcaatat tacaaacaat agctctttgc tggtaattat tttcactaaa
   909361 ttcaatacct gctaattctc taacatttga tttagcccca tctgcaccaa ccaataaacc
   909421 acatttgatt ttatgattac tattcaaatc aacctgataa ccattatcaa ttctattgat
   909481 agcagtgagt tctgtacaaa taaactcaac acgagttttc tctaatatcg tatacattgc
   909541 agattgtatg gcatcatttt caataatata acctaattgg ttaatatctt catcttgact
   909601 atgaaaatct aaactaccat gagaattctg atcccaaata tgaatatcag taaacgcata
   909661 tttacgctta attaacctcc aaacaccaat atttcttaat aacgtctctg atttagatgt
   909721 aattgcacta acacgtgtat ggtacttatc ctgcaatttt ggattaaaat agttaggctc
   909781 aataataaca atcttcaaac ctttattaat catagataag gcaaatgcct gtcccaccat
   909841 gccaccacca ataataacaa tatcatattg taaattgttt tcagaactca ttacacttct
   909901 cctgcaatag tcatctgctg tattaaaaca gaaccaactt taatattatt acgatagtcg
   909961 atatccgaac caatatgctc aatacctaat agcatttctt taagattacc agcaattgta
   910021 atacctgata ctggatattg aattttacca ttatccaccc aaaaacccaa agcaccacga
   910081 gaataatcac ccgttgtgtc atttacacct tgacccatca attcagttac aactaaacct
   910141 tggtgcatat ttttaattac ctcatcaaga ccaccttcaa atttatgttc aatcataaca
   910201 ttattcacac cacctgcatt tgctgtagtt ttaaggccta actgattagc tgaatattgt
   910261 cccataatat aactttgaac ctgaccattc ttaacaaaat attgttgttt ttttagcacg
   910321 ccatcttggt caaatgcttt agaaccaata gttttcttaa ccaatggttt ttctaataaa
   910381 ctaatactac taggcattac tagctggtca acactatcca ataaaaacgt tgatttttta
   910441 tattgtcgag caccatttaa tgcacccatt aattgtgaaa acaatccacc agataaacgc
   910501 gatgtaaaaa taactgggca ttttcttgat tctagagacc ttgaagcaag cttattaaca
   910561 gctaaatttg ctgccttttt acctactact tctggcgact ctaaatcaaa attatccaat
   910621 gctactgtat attcataagc cgtttgcata tctctatctt gtttagcaat aatagagcaa
   910681 tgcaatgaat gcttagcacc ttgttgcgcc gccatcattc catgtgaatt aatatataaa
   910741 tccttgcctt gaaaacttga taattcagca ccatctgaac tatcaatata tttttgttct
   910801 aacgccgctg tttcacaacg tttagctaag tcaacactat ggctcggatc taaatcccac
   910861 ggataataca aatctaaatc aggaggatta aacgccatta attcttttgg tgccaaacca
   910921 ttaaatagat cttcttgtgt atatttagca attagacaag cagattctat agttttagca
   910981 ataccctgct tatttaaatc cacactagat gcatgtcctt ttttgttacc catataaaca
   911041 ttaatatcaa acattttatc taaatgatgt tctaaagttt caattttacc taatcgaaca
   911101 gcagtggaaa cgccagagct tgaacttaaa aaaatttcat aatcagtaat atcatacttt
   911161 tttaaaaaat caatagcaaa ttgtgcagta ttttctagtg aaaatgacat aatgaaatta
   911221 tacccaataa taaaaacata tcagcttaga aaaatgcata atatcatata taatcataaa
   911281 atatcataga ttgaattggc atccataatg ccataattcc caaaataata attaacaaac
   911341 cagataagcg ccgaatccaa agtttttgga ttaaaaaact catctgagta gataaaactg
   911401 acattaacaa caagcttggc aacgtcccta gtccaaatga caacataatt aaactgcctt
   911461 caaacatcga gccagataaa atagaaaagc taagtgctcc ataaactaat ccacaaggaa
   911521 tccctcccca tagcaaacca ataaaaaatg cacttctaag atttttaatt ggtaaaaact
   911581 gttgagttaa tggctgtaat tttacccaaa atttagcgcc aaatttttcc aatatttgaa
   911641 tgttgaatga ccaattacca atatataacc caaccatcac catcaacatg cctgagaata
   911701 ttcgcaaaac cttatcaaac acactcattt gtaagacttg agttaatagc attccaaata
   911761 aaccaaaaat agcacctagt agtatataac ttagaattct accaagatta taatttagat
   911821 gaaaaagtgc tatttttttt ggattactcc taacttttgg gtcaagtccg gcactaagca
   911881 tacccactat accaccacac attcctaggc agtgcacccc acctaatagc cccattataa
   911941 acacactaat aagaatactc attaagcatt gttaccgttc atagaacgtt ccacttcaag
   912001 taaatgaata cgtctagaat cagtttttaa aattttaaaa ttaaagccct gtaacgatat
   912061 ttcatccatt tgctcaggca aacgagtaaa tcctttaatt accaagccag ctactgtgtc
   912121 aagattttca acttgcaact tcaccttaaa aaactcatca aattcttcaa taggggtgtt
   912181 ggccttaagc agaaatctac cttcaccaaa atcaataata ttgtcttctt ccaaatcatg
   912241 ttcatcttca atctctccta cgatttgttc taatacatct tctagcgtta ctaaacccgc
   912301 aatttctcca tattcatcca tcacaattgc catatgtgat tttttttgtt gaaaatctct
   912361 taataatgca ccaagggttt tgctttctgg tacaaataga gagtctctta aatattgctt
   912421 ataattaaac tcaaagttct gcttttctac caaaaaccca agcaaatcct tagccaaaat
   912481 tacaccttga attttatttt tatcactatt aatgattgga aatctagagt gtgaggattt
   912541 aatcataata tcaagcaatt ctttagtggt tgattgatgc tcaatcataa ccatcttgga
   912601 ttttggcacc attacatcac gaacttctaa cttttcaagc tgcattgtac cttcaataat
   912661 tgagcgagaa ttagagtcaa taatataatt ttcctccgct tctttaagca ttctcaaaag
   912721 ttcatcactt gaacgtagtg gtatatgcag ataacgtttt ttaagtcttt gtaaaaagaa
   912781 ggatttcagt gaaaattgtt ctttattcat taacacctat ataaattata gaattatttt
   912841 aacaaagttc aagttttttt accactacgc atcatttttc cttgtgcagc tctctcctta
   912901 cgtacaacct tagggtcagc aattagtgaa cgataaattt caatcctatc tttttcccta
   912961 agaaccgtgt caagcttaac aattttacca aaaataccag ttttttgttt aataaggtca
   913021 atctctgggt atatgctcaa tatactggac atcttaattg cttgctgtaa agttgttcct
   913081 tcacttattt ctaattcaag caaagtctgc ttatctctta aggcatacac aacctcaatt
   913141 ttcatcacaa agttgttgtg cttgtttaaa atcaagtgta ccttcataaa ttgcacgccc
   913201 agtaatcacc cccataatac caaaatgtac ctcagttaat aatctaataa tatctcctat
   913261 attagtaatt cctcctgagg caataatagg aattgaaatt tgcttagcaa gattaactat
   913321 tgcctcaaca ttcattccct gcatcattcc atcacgtgca atatctgtat aaataatgga
   913381 attaatacca tcttgttcaa attttttaga taaatccacc acattcaagt tcgttttttg
   913441 cacccaacct tttgtcgcta caaaaccatt atttgcatct aaacctacaa tcaccttatt
   913501 agggaattca cgacataatt cagatacaaa ctcagagtct gttactgcca ttgtaccaat
   913561 aatcaaataa ctaactcctg cttcaatata agtattagca attttaatat tgcgaatacc
   913621 acccccaatc tgaactggca aatcaggaaa tgccgataca atctcagtga tactagttga
   913681 attaacaggc cttccttcaa atgcaccgtt aagatccact aaatgcaacc tgcgtgcacc
   913741 ttgctctacc cactgcgttg ccatttcaat aggattacta gaaaataccg tcgtatcctc
   913801 cattaaacct tgccttaaac gaacacattg tccatctttt aaatctattg ctggaataac
   913861 aatcatattt ctcttattgt attaacaata ccaaatcact ttaacccaac atgctgattg
   913921 atatgctaac cacttctaaa atttggtaat aaatcctaat aaataagtac aaattattaa
   913981 ctatacattt taataaccgt ttattttcct tgttcttcta ttctcatatt ataactttta
   914041 gacacttatc tttcgtataa attttactac tctcaatata ttttatattt taattgcata
   914101 acaaaaagaa aaagtatatt taacaccatg tcaatacact caagcaacaa cctatatcaa
   914161 tttaattaag atatttgttg tataaaattt tctctcttta ggtattttat ttacaccaaa
   914221 actacattaa ccgtatttcc aaactctttt aagtcaaaaa ttaacataat atttacaatc
   914281 ataatgaaac ttttttaagt caaaaaagta agtttattgt tatagaaatc agcaacaatt
   914341 aataaattac tatttaaatt acgtagcata taaattgcct tttacttcag aatatgacag
   914401 caaataagcg ttcaatttat ctcatttaag agcttgttat agtttaataa taaagaataa
   914461 cttaaataag taaatgttgt atctcctcac aggagaagta gttactttaa ttggtctttt
   914521 attaaaagaa aaactaatct tctcatacta agttttatcc ctataatcaa caacaattta
   914581 acttgcttct ttgaaaatat tgttaacaag aactatttat gttgaaacat gtcctctaaa
   914641 ccttttaaat tgttacctat ctagtacttt atcgtttcgc tatatataat aattatttaa
   914701 accgtctttt gtaagggtca ttattgtcaa ataactagct attaaataaa ttaacatata
   914761 taaataatag tttaccaacc aacaaacatt ataatataag acttgattta gtaggatact
   914821 tacctggctt aactacttac aatgatagct ggtaattaaa gtaagctatc taatcccaat
   914881 ccttcataaa atttaaataa gctgatgtca atactttgtt taatttattc aaaatccagt
   914941 agcaatccaa taataatata aaaattatat atagtaaatt tacaacaatc atccattttg
   915001 taaaaaattt aaactttaaa gtcataattg tactgcacac ataatctttg cttttatgta
   915061 tcatactttc agacaaatca accatcaaaa actatagcaa gttaacctat taaatataca
   915121 cttcaatggt tactagtata atacatcacg tcttattaac gtatagaaaa acaatttatt
   915181 taatttgact caattcttct atattccatc taggcttaat gttaatttca taattggtat
   915241 cgcactgtcc atcgcttaag cgaaaatgcc cagctaaagc tatcatagca ccattgtcag
   915301 tacaaaactc ttgccttgga taaaagatat ttacacccac ttttctaccc atttggttaa
   915361 gttcactacg caaagataaa tttgcactaa caccacctgc aaccacaagt gttattcttc
   915421 cagtcttctc taatgccctt ctacacttaa tcataagtat ttgcgtagta gcaacttcaa
   915481 aagctttagc aatatctgat tttttattag gatgtttagt aaaggtatta cgtgcaaacg
   915541 tttttaaacc actaaaacta aaatcaagcc caggacggtt aaccatagga agtggaaact
   915601 taaaagtatt agtatcacct tgtttagcaa gcatttctaa agcagggcca ccaggataac
   915661 ctaagcctaa aatttttgct gttttatcaa acgcctcgcc tactgcatca tctaaagact
   915721 tacctaaaat tttatattgg ccaatggcct taacatcaat taacatagtg tgaccacctg
   915781 aaactaacaa agctacaaaa gggaatttag gctgagattc ttctagcaaa ggcgctagta
   915841 aatgtccttc catatgatgc acagctaaag acggaacgcc caaactccaa gccaaagatt
   915901 tagccaacgc acttcctacc aaaagcgcac ctgccaagcc tggtccagct gtataagcaa
   915961 tgccacttaa atcttgcaag gtaaattttg catttgttaa aactgtttta attaaaggta
   916021 acactctttg aatatgatca cgcgatgcca actcaggaac cacgccaccg tattcgctat
   916081 ggatttcaac agatgaaaat aacttatgac caataagacc aagctcagaa tgatacaatc
   916141 caacacctgt ctcatcacaa gaactttcta tacctagcgt aataaagtca agtttagcca
   916201 cctattaatc ctaatgagtg tacattgtaa agataagatc atacccttcc taaataaact
   916261 tcacgaaccc tttcattgta aagaatttgt tctttactac cctttgcaat aataacccca
   916321 ttatgtaata cataggagtt attgcaagta tctagcattt cacgataatt atgatccgta
   916381 attagtatgc caatatcttg atctttcaaa tagaaaataa ttttttgaat atctactaca
   916441 gaaattgggt cgacacctga aaatggctca tcaagtaata taaattttgg attcattgct
   916501 agtgccctag cactttctac tcttctcctt tcaccaccag ataaactaac accgttaata
   916561 tggcgaatat gttcaatact aaactctctt aataatttct ccaatctgtt tactctctgt
   916621 attttatcaa aattagagtt tagttgtaac accgccataa tattgttttc cacagaaaga
   916681 ttacggaaaa tagaaggctc ttgaggtaaa taactaagcc ctaaatcagc acgtttgtgc
   916741 attggtaaat gatcaattct cttattgttt aagtatacct ttcctgaatt tgacttaacc
   916801 aaaccacaag taatataaaa acaagtagtt tttcctgcgc catttggacc taacaatcca
   916861 accacttcac cacttttcac aaaaaatgac acatcattaa ctacattcct acctgaataa
   916921 gatttgctaa tattttgtat gattaaggcg ttactagtca tatataacaa atatcaatta
   916981 ttttaacagt tctaatcatt aacctaaacc aaataataaa caaaaatacg taaatgttag
   917041 aatacaaaac actattgtta atattgagta aaaaacctaa tttaaaacaa aatctaaaag
   917101 ggaccacatt aaaaatgata tttctggtta caataatata aacatatttg aaaatatgaa
   917161 agacatcata atcctaaaaa aaataactca gttacaaatg aaaaattaac taaataccgc
   917221 atcaatcaac attaataaag atgtaaaaat tcagatgaat aaaccagttt aatgccacat
   917281 tgagtttcaa ctaacaagac tccttcgtga ttgataccaa gacaagtacc actaaacaac
   917341 tgcattttat ttgtatgctt aacctgctta cctaataaat aatctatttt agaccactcg
   917401 ttataaaact tatcaaaacc acttgattca aaaatatcta gatattctaa tatcttatta
   917461 attaaatttt tacttaaatg tagcttatca atcggtatta aaattatttt ttttaaatct
   917521 atccaaggcg tttcacactg aaaatcttca ttaaaatcaa catttagtcc taaaccaata
   917581 atgactgaat gatagtcacc ttgaagtgaa ttctcaatca aaatacctgc taatttctta
   917641 tccttaaaat aaagatcatt tggccatttg agtttcaaat caaaaatacc atatttttct
   917701 aatacatcaa ctaatgcaag accaaccacc aaacttaatc cgctcaataa aattctacta
   917761 agaaaaacac gacgtattga taaaataatg cttgcatctt tctgactcaa ccatttccta
   917821 ttatattggc cctttccaca agtttgttca gaagtaacac aaacttgcgt tttcatacaa
   917881 aaagctaact gggctaaata atcgttggtg ctagatattg aatcaaaaac aaaacattga
   917941 atatcatcac ttaaataact tgatagattt gtataattat aagtattcaa gcaaaataat
   918001 aaatcttaac taagttatgg ttttttataa tttaacgttt agtaactcaa aaggttattt
   918061 ttaataaatt tctaagttat cactatgtta tatgtcactt taaaaaagag atagaaaatg
   918121 atatattacc ctaaaaggtg tttaagacta aactagaaga ctttaagttt ctcatataaa
   918181 aatccaaaag tattgataat gttcattcat atttcatttt aactaattta attggttaaa
   918241 atagttacat ttagctaaat attatatcat gaaactagca ttaggagttg aatacttagg
   918301 cacacatttc cacggctggc agtgtcaaaa atcgaacatt cgaactgtac aacaagtaat
   918361 agaacaagct ttatcaagcg ttgccaatca acctgtaaga gtattttgtt ccggtagaac
   918421 cgatactggc gtacacgcca cctgccaggt tattcatttt gaaactaaca tcaagcgtaa
   918481 aaataaggct tggctatttg gtggcaatgt tcacctgcca agtgatgtta acttcacttg
   918541 ggtaaaaccc gttgatgata atttccacgc acgatttagt gttatcacta gacaatataa
   918601 ttataaaata cataacacaa aaatccgttc ttctatcata gcaactcatt cattatggga
   918661 accaagaaaa ttggatatag tagcaatgaa taaagccggc caatacttaa ctggaaaaca
   918721 taacttttca gcctttagag gaagtttatg ccaagcaaaa tcccccatta aaaacattga
   918781 gtttataaaa ctaaccaagc atgatgataa tattttatta gacataaaag ccaacgcttt
   918841 tttacaccat atggtacgca atattgttgg cacactgctc aaagtaggta aaggagaaaa
   918901 acccattgaa tgggtgagag aggttttgaa tagcaaacaa agaaaacaag caggccctac
   918961 cgcaccacca caaggacttt actttattag agctttttat aaaaatattt aatactaaaa
   919021 aagacaacgt ctaaatatct tattttaata tattactaaa acaatcaaca tatatttatt
   919081 aataaatata tgttgattaa attcgcacaa acaacaacat gtttaatcaa aaaattactt
   919141 ataagaagga aataactatc acttagttta ataaaacaaa tatttttaat cagtaacact
   919201 tattagcagt gattagcaat gttatgatta tggtataatt tttttattat tttgtacact
   919261 ttttaaaatt aaaatcatgt tcaataaaaa aaatatttca gctattattt ttgctatttt
   919321 tgccgtatgg ctctcaacaa ttgcaccaac tacttctatt tcttggatgt tgggcgttct
   919381 cgtattaaca atttacttat ttgcttttga agtggtagag gttgatgaag ccgccattac
   919441 cattatgatt attttagggc taagctcttt accatggatt tatactttaa tggggctaaa
   919501 agaaggattg gttgacaatc aaagactatt tgatggattc tcttctaatg cagttatgtc
   919561 aattattgca gtaatgatta ttggcgcagg tttggataaa acaggattaa tggggaaggt
   919621 tgctactttt attcttaaaa taggtggcac ctctgaacca agagtaattc caattatatc
   919681 ttctactgtt ggatttatct catcttttat gcagaatgtt ggtgcagctg cattatttat
   919741 ccctgttgta agtcgtattt catcacgttc aggtatccca atgtcacgat tattaatgcc
   919801 aatgggattt acagcaattt taggcggcac aataaccatg gtaggttcta gtcctttaat
   919861 tttgcttaat gacctaattt taaccactaa ccaaggacta gaagttggac aggaaatgaa
   919921 tacgtggggt ttattctctg tcacaccaat aggtattgca ctagtaataa caggtattat
   919981 atatttcgtt attgctggaa aatttgtctt acctgtaaca aaaaaagaac agttagaatc
   920041 tgtatctgcc attgaacact ttcataaagt ttacaatata gattatgatt tatttgaggt
   920101 taatgttcct acagattcca acttaatagg catgatgctt gatgatattg aaacaactgc
   920161 taaaattaga atcatcgcaa ttcaaaccat tgaaggagaa acatttattg gacatcattc
   920221 tgttgaaaga agtactgcaa ttaaacccca aatgacctta ggtgttttaa ctaaaaaaga
   920281 gcatttagat acttttattc aagagtttca tcttaaacta tcagacacaa ttgaaaaatt
   920341 ctccaattta ctatccacac aagaatgtgg cacagcagaa attgttatcc cccctaattc
   920401 ttcgctcatt aatcaaagtg ctagagacgt atggttacga aaaacttatg ggatcgccat
   920461 ggtagcccta catcgtggtg gcgaaaccat gcaagaaggt gaaggtattc gtaatatacc
   920521 atttcaatct ggtgatacgt taattgtcca tacacgttgg attgaccttg atagactaca
   920581 atccaatact gattttattg ttattacttc tgagtatcca agacaagaag aataccgacc
   920641 tgagaaaatc aaatgggcaa gtattttctt tgttattgca cttttcttag tcttatttac
   920701 agatattaaa ctttctatag cgcttatgac tggtgcttta ggtatgattt tatctggtgt
   920761 tattaaaata gaagaagctt atcgcgtcgt ttcctggaaa acagtatttt tattagccag
   920821 tcttattcca ctaggtatgg ccgtgtcaaa aactggtact gccttatgga ttgcacaaga
   920881 aacagttaaa gtagttggag atatggcacc ttgggtcata ttaacctcaa ttgtaatatt
   920941 ggcaactttc tttacattag tcatgtctaa tgtaggtgca accattcttt tagtacctat
   921001 tgccgttaat attgctattc aagtaggcga aaatcctgca gtttatgcac tagcagttgc
   921061 tattgcaact tcaaactcat ttttaattcc tacacatcaa gtgaatgctc taattatggg
   921121 tcctggtggt tataaagtag cagattttat caaagcaggt ggtcttatga cagtactatt
   921181 tatcattgtg atgatgtcaa tgatgagtat catcttttag ataactactc taatccttaa
   921241 cttaaagaga gaaacgttct taacgagaca aaaaatttaa attcaatgca agcaaaaaaa
   921301 agactgattg atggtaatca acgttttatt gatggcacta ctaccttgca tcatcaatta
   921361 cctccacata aacatataaa aaatatacaa gatcaaaaac ctttcgcaat tatattaggc
   921421 tgttctgatt cacgagtacc tattgagacc atctttgacc aaaattttgg agatttattt
   921481 attattcgta ttgcaggtaa catagtagca ccatcacaaa tgggtagtgt tgaatttgca
   921541 atatcaaaat tcaaaacagt cttaattgtt gtactaggac attctaactg tggcgctatt
   921601 aacgccacca ttgatgaatg tatcaataaa acacatttat caagcagtct tcactctatt
   921661 actgatagaa taaaaccatc aatcctacct ttaattaact tagatttacc caatcatgaa
   921721 ttaatgaaca aagctgttaa agttaatatt attaattctg tcaaacaatt acaaagccaa
   921781 tcaacaataa ttaaagaatc tatgaaaaat aataaactaa agattatagg tgccaactat
   921841 tctttagcat caggaatggt tcagttcctg acttaatttt cttaatcttt tgtgattgaa
   921901 actaaattgt ttaaaaattc tcatcccaat caactaaaat aatttgattg tttatatcta
   921961 cttgtattaa aaatggagaa atataaggca cccagtgctc ttttccaccc ctaactacaa
   922021 gtacgttatt cgaaccagta tcaactaaat taaacacttt accaagcaca aattgtgctt
   922081 tattaactac ttctaaacca attaaatcat tccagtagta ttcaccttct ttgagtctta
   922141 ataattgtga tttcttaata tacaaattaa tatctatata gactctagct tgttctttat
   922201 caaaaatatc tttgatttgt gctacaatag ttttagcttg cacacgacct tgtgaaatat
   922261 ttaaagtttg ccaatgacta tcaacattga tataccatgg ttgataggat aaaatattca
   922321 cccttggatg ggtatgggat aaaactttaa cccaaccatt aataccaaaa aatccattaa
   922381 tcctcccgat taatagcttt ttattattag atattaaaaa ctctgaatta ctcagcgatt
   922441 tctactgctt ctgctattaa tttagattta atcaaagatt ttttgctgat ttaacagcaa
   922501 tatctctttc acgaattaaa ggatctttaa actctttaac aagctgctta acacgatcag
   922561 aaatttgagc accttttgat gtccaatatg ctaacctagc ttcttcgata ataagcctaa
   922621 cttcttgtcc atgggtaact ggattaaaat atccaagtcg ctcaatgtaa gcactatctc
   922681 tacgtcttct agagtctgtt gcaacaattg aataaaaagg ttttttcttg gctccgcccc
   922741 gagctagtct aattttaacc atggtttttt attcctaatt tatattatat aatatgtact
   922801 tatacattac ggcataagac tagttattat atcagttgtt tgattgcttt tgctagtttt
   922861 tgtgcatcac ctgtataagt cataggtgtt aacttaaaca aggttatctt agcttcatct
   922921 ggtatatcaa gatctttgac aaattctacc aacacttgtg cattaatcgt tttaccacga
   922981 gtcagatctt taagtttctc atagggattt tcaatgccat aacgacgcat aaccgtttgt
   923041 attggctcag ctaacacctc ccacgaatta tctaaatctt gggttaattt agccttatta
   923101 ctctgtaact taccaatacc cttaacaata gatgcatacg ctaccaagca atgtgcacaa
   923161 ctcacaccta gattcctaag tatagttgaa tcggataggt ctctctgcca acgtgaaatc
   923221 gccaacttat ctgctaaata catattaatc gcatttgcaa tacccaaatt accttcacca
   923281 ttctcaaaat caatcggatt gactttatgt ggcatggtag atgaacctac ttctccagta
   923341 atagtttttt gcttgaaata accaagagaa acataacccc aaatatcacg acaaaagtca
   923401 atcaaaactg tattaaaacg attaatcgaa tggaaatact ctgcaatata atcatgtggt
   923461 tcaatttgcg tagtatacat agcataatta acgccaaaac tttcaataaa attctgagaa
   923521 atatactgcc aatctaaatc tggataagca caaatatgtg cattaaaatt accaacagaa
   923581 ccattaaatt tacccataat tttcacactt tctaactgct ctatttgtct ttttaaacga
   923641 taagcaaagt tagccatctc cttacccaca gtactcggag aagctgtctg tccatgcgtg
   923701 cgagacaaca tcggaactga gacattattt tctgccaatt tagcaataaa tgataataat
   923761 tcacgcatct tagttagcat gatattacgt ccttctaaca acataagtgc atatgacaga
   923821 ttgttaatat cctcagatgt acaagcaaaa tgaaaaaatt cactaactgc ttcaagctcg
   923881 ctatttcctt tgatcttatc ttttaagaaa tattcaaccg ctttaacatc atggttaatt
   923941 gtatgttcaa tcatcttaac ctcttgagca tcaatcaatg aaaaattagt aacaatatca
   924001 tctaaaaact tagttgcttc ttgactaaaa gatgatactt cttttatacc gatattatct
   924061 gccatatctt gtagccactt cacctcaatt aaaacacgat atttaattaa gccaaactca
   924121 ctaaaaatag agcttaatat ttcagttttt tcaaaataac gcccatcaat aggagatatt
   924181 gctgttagtt cagttagttt cataagacta tttagtataa caaattaatt actcatcata
   924241 taaaaaaata agattatgat atgaaaaaag atacagaaat aaaatgataa aattatacac
   924301 tttattgttt tataatgaga actcagatga aatctgtata ccttgaacat gttaataaac
   924361 gccaacaaaa taatttaccg ccaattgcct taaataaaca acaaactgaa tcagtaatta
   924421 ggcatttaat caaagataat cattcatcct tttatcttga tttactcacc catcagatac
   924481 cacccggtgt tgatgaagct tcttatataa aggccaattt tttaagtagt atttccaagg
   924541 gagatcaatc ttgtcatagt atttctcaga cacatgctac ttttctgtta ggtactatga
   924601 tgggtggtta taacattaag cctttaattg aactattaga tattgatgct acaaaagaaa
   924661 atgcacaaat agcactagca aataccttat taatttatga agcatatcaa gctattatgg
   924721 ataaatctaa aaataatatt tacgctagaa acgttgtaca aagttgggca gatgcgcaat
   924781 ggtttaacaa aaaaacaccc ttatctgaca aaattaaatt aacagttttt cgtgttgaag
   924841 gtgaagttaa tacagatgat ttatcacctg caactcaagc ttggtcacgc ccagacattc
   924901 ctttacatgc acagtctatg ttaatcaaaa aaatgaataa cccacttaag acgattaaaa
   924961 aactcaaaca aaaaggccta ccattagtct ttgtgggtga tattgttggc acaggatctt
   925021 cacgaaaatc tgctattaac tcagtacttt ggcacattgg tcaaaatatt aattacatac
   925081 ctaataaacg aagtggtggt attatactgg gtggtaaaat tgcaccaata ttttttaaca
   925141 ccgcgcaaga ttctggagcc ttaccaattg agtgcgacgt tggcaaaatg cgaatgggtg
   925201 ataaaataac aatttatcca tttaaaggaa aaattactaa tagcaaaggt gagatcattt
   925261 caacttttat catctcacca actacactgc ctgatgaagt acgcgcaggt ggtcgaattc
   925321 cacttattat tggcaggggt ttaactgata agactcgaca agaccttggc ctgcctatct
   925381 caactacttt tttacgacca caagcaggta cagaagagca aagtattagt caaagtcata
   925441 ctggttacac actggcacaa aaaattgttg gtaaagcttg tggggtaaat ggcatttatc
   925501 caggcactta ttgcgaacca cacatgtcta gcgtaggttc acaagacact acaggagcaa
   925561 tgacacgtga tgaactaaaa gaattagctt gccttgaatt ttcagcagat ttagtcatac
   925621 aaagtttttg tcatacagct gcttatccta aacctattga tttagaattg caacactcat
   925681 tacctaattt tatgcactca cgtggcggtg tatcactaaa accaggtgat ggaattatcc
   925741 attcatggct taatcgcatg ttattacctg atacagtagg aacaggtggt gactctcata
   925801 cacgctttcc tattggtatt agttttccag ctggatctgg actagttgcc tttagtgctt
   925861 caattggtat gttaccactt aatatgcctg aatctatctt ggtacgtttt accggtacaa
   925921 tgcaatcagg tattacctta agagacatag tcaatgcaat cccatacaca gctatacaaa
   925981 gaaatctact aaccattgat aaatctaaca aaaaaaatat tttctcaggt cgtattttag
   926041 aaattgaagg gctaaacgat ttaaaagtag aacaagcatt cgagctagcc gatgcctcag
   926101 ctgagcgttc tgctaatggt tgtactatta aattaaataa agaacctgtt atagaatact
   926161 taagatctaa tattgcttta ttatcttcaa tgatcaataa aggctatgaa aataaaaaaa
   926221 ccctcgctag acgtattcaa gcaatacaaa aatggctgga agaacccgaa ctgctaatag
   926281 cagattcaga ttgtaaatat gcttccatta ttgagatcaa tcttaatgaa ataaaagaac
   926341 caatcttggc atgtccaaat gatccagatg atgtcaaact actctcagaa ctagctaata
   926401 ccaaaattga tgaagtcttt attggttctt gtatgactaa tattagtcat tttagaatgg
   926461 ctgcgcaaat gttaaaagat gaattaaata tagcaactga attatggatc gcaccaccca
   926521 ctcgaatgga taaagcgcaa cttaaagcag aaggtgtata tgatatattt aataaactaa
   926581 ctaaacacgt cgaaattccc ggctgttctt tatgtatggg taaccaagca cgagttaaaa
   926641 acaattccac agttgtatct acctcaacac gtaacttccc taaccgttta ggaaataata
   926701 cagatgttta cttatcttct gctgaagtag caacaattac tgcaaaacta ggacatatcc
   926761 caacaaacat agaatatcaa caagcaataa agagcattaa gccaatagaa gaacaaattt
   926821 atcaaaatct aaattttgac caattagaag aatataaaga cgagataaat aacctatcac
   926881 taaaaaacat cttaaatgca taatcaataa aagaatttca aataagaaat tctttttact
   926941 aatatttgat taagaaaagt tacttaatct taacttcctt atacatcacg tgttttctaa
   927001 caactggatc aaatttttta acttctacct tctccggatg gagacgttta tttttagtgg
   927061 ctgtataaaa atgacctgtt ttagctgatg acactaactt aattgtctct ctcataaact
   927121 tgactcctta aactttccgc gtgcacgaat ttcagttaat acaatgttga tacctttttt
   927181 atcaataata cgaaatcctt tagctgataa cttcaactta acaaaacgat tctcactttc
   927241 tacccagaaa cgatgtttgt gaagatttgg ataaaaacga cgacgcgttt tattattcgc
   927301 atgagataca ttattaccac taattggtcg cttacccgta accatacata cctttgccat
   927361 aactcaccat ctaaagaatc taaaagatag gaattatatc ttaaaattat ttaactttca
   927421 aagctaaatt atacaaaaaa tctattcact attaaccgaa caaacggtat catacattaa
   927481 tattggaggg atggcagagt ggctgaatgc accggtcttg aaaaccggca agggctaata
   927541 cccttctagg gttcaaatcc ctatccctct accatgataa cacgcaacac aatactcact
   927601 aaatattaag acaacattta tttaatctta ataaacaaac cttttgttaa ctattcttcc
   927661 aaaaagttta ccacgtccca catataaata tcaacattac ctgataaatg ccaaataatt
   927721 cacttttaaa tataaagtta ctattattaa attaatttac actaacatta taagaaaaat
   927781 atgattaaag caataattct ttttacactt ttattcgata cttttagatg acatgcatat
   927841 aaactattgg attatcttat ctagtaaaac aaatatttat caacaaagaa atatttctct
   927901 tacacacaat aaatcgttta aaacagcaaa acagaactta gcattataaa ttaaacatta
   927961 atatacttga taccagttta aatcacaaaa aagaaaaact atagctctta atctaaaaat
   928021 agaattataa ctgagaaaaa taatagtcaa tattttaaac cataattatc tctgtacttc
   928081 aatacgatca attaacgcat gattattgcc ttgttttaga taatcaacca cattcgataa
   928141 attaataata ctgaatactg aaataccaaa attctgctca acttcctgaa tagcagattg
   928201 tccactctta cctttttctt ggcgatcaac tgccacaatc acacctttaa cagtagcacc
   928261 atttgcttta ataatatcca ctgcctcatg aatagcagta cctgctgtga ttacgtcatc
   928321 aataatcaag atattacctt caagtgaatg accaacaata cctccgcctt ctccataagt
   928381 ctttacttct ttacgattaa aactataaga cacatcttta ttaaaattat tattaaatgc
   928441 cacagctgtt gccgttacta gtggaatacc tttgtaagat ggaccaaaca aaacatcaaa
   928501 atctaagcca ctattctcaa tcgctatagc gtagaatttt cccaattgag aaagatactg
   928561 cccagtatta aatactccaa cattaaaaaa ataaggacta attcgaccag attttaaggt
   928621 gaaattacca aacttaagcg caccactatc caatataaac tctacaaagt cttcttgata
   928681 ctgttccatc taattttcct ataaaattat tctgatgata agaattataa cgactaatgt
   928741 caatggaatt cgtgctgctg aaagaaaagg ttttttaaat tggataaaaa atcaaaatgc
   928801 agacgtagtt tgtctgcaag aaatcaaggc aacagaagaa caattagatg agcgatttta
   928861 tccagaagaa taccattgct attatcaacc agcccaaaaa aagggctatt ctggcacgac
   928921 aatttttacc aaacaaacac ctattcaagt aattaaagaa agtccatgga aagatattaa
   928981 ttttgaagga cgatttattc aagttaactt caaaaatttt tcagttattt caatttatat
   929041 acattcaggt agtgccaaac aagcacgcca aaatttaaaa atggaatttt taactgaacg
   929101 atttatgcct tacttacaag agcttaagat aagcggacgt aaggtaatta tttgtggtga
   929161 tatgaatata gtacaccaag aaagagatat caagaattgg aaagccaatc aaaaaaattc
   929221 aggctgctta ccagaagaac gcgcttggtt agataagtta ttttttaaag ttggctttat
   929281 tgatggattt cgtgaggtca atcaagagga tcagcaatac acttggtgga gtaatcgagg
   929341 acaagcatgg gcgaataata tcggctggcg tattgattat caaatcctca ctccaaatct
   929401 caaaggcaaa gttaaaaatg ctaatattta taaaaataag cgtttttcag accatgcgcc
   929461 aattattatg gattatcaac tatgacaata ataatcacaa gtctacatca aatacatcat
   929521 ttctaatagt ttaaataaga taaataaaca aaaactataa aaataaaata ctctaattca
   929581 acactagttg ttattgctac atttgaactt taagcgtttc taaatactgg gttacttagc
   929641 aaagtaacag tgttaaatac tagttagtta cattaaattt attcaaaatt ttcaactttt
   929701 ttgattaatt caacattgtt aaatcattac ttaaacgatc atttatgaca tactatctcc
   929761 atctcttaca agtttaaatg taacaaaggt cgatgatagc taaagtctat ataattaagt
   929821 tacatacaaa taatctagtt ggaactactt aaaaacaata ttaattatat gtaacattag
   929881 gatgttctga ttcattaaac aaaaaaattt gtaaaggaaa gtctcactta ctaaagaaaa
   929941 acagaacctt attaacctaa gcctaaacat tctatccatc ctactatcat aagagatttt
   930001 atcctattta ttctaggtac aaataaagtc atgataaaca ggtaagcaga aaactatttt
   930061 tttggtttaa gacttataaa tataccatac atcatttaac tttcaaacgg taaaatacgg
   930121 cttattataa caaataactt ttataaaata cttgttcctt tagatttttt tattttaatt
   930181 ttcttggcaa caatccacta aatactgttt atatttatgc taatattttg ataaatcaga
   930241 taagaaaaat taaaagtttt gtacgtcgtc ctggaagatt aactctaggt caaaaaatgg
   930301 gtctgactaa gttttgggaa gatcatggaa tagatttacc aaaaggcaaa attaatttaa
   930361 atactttatt tgttaaacaa caaaaaattg ttttagaagt tggttttggc aatggtgata
   930421 gtttactgaa aatggcaatt aatacacctg atagaaattt tttgggtatt gaagtgtatg
   930481 aagcaggcgt tggtcagtta attaataagg cacacaaata ccaattaaat aatcttaaaa
   930541 taattaaaga agatgctgtt aaagtattaa caaatcatat agaagatagt agttttaatc
   930601 tttttcaaat gtttttccct gatccatggc ataagaaaag gcattttaaa cgtcgattag
   930661 tacaaactga ttttttaaat ttgttatcac ataaaatgat aaaaagtgga aaaattcata
   930721 tagtaactga ctcgaaacat tatgctattc atatgatgac agtcttagaa agacacccta
   930781 actttaaaaa cacacagaat gctcctatct attcaccaag acctgaacat caacctatta
   930841 ccaagtttga acaacgaagt catagacttg gacatgatgt ttggaatttg atctttacaa
   930901 acgagaaata atatgatttt tccaatattt gtagtcatga ctctacttga aatttatata
   930961 ctcgcctcag taggtgctgc tattggtggt tttttaacag ttttattagt tatcatcaca
   931021 gcatttattg gtttcttttt attaaaacaa caaggttatt caacaatagc taaagcgcaa
   931081 aatacaatct caaataacca aacatctacc tttgtaaggc ttgaaggtgt agtaattgtg
   931141 gtatctggag tattgttatt aactcctggg tttattactg atatgattgg tctattaggt
   931201 ttattaccct tttctagatc ttattttatt aaccgaattt tagaaaaaaa tgcaaaaaaa
   931261 atatttaaca ataatcactc tggttctatt attaaaaccc aaaacaatca acctcaacaa
   931321 agtaatgaaa aaaacactat tgaaggtgag ttttgggagg attaaacact cttagtgatt
   931381 ggttaaatta ccaagataac ttacatttta agaaaattga tttagggcta gaacgtgtta
   931441 caaaagttta taaaaaacta tttccaaaag gcatactctt tcaagtaatt acggttgctg
   931501 gtacgaatgg taaaggttcc actgttgcct ttattgatag catctaccaa caatcaaact
   931561 ttaaagtggg aaaatttagc tcgccacaca ttcttaaata caatgaacgc tttgtgatta
   931621 atggtataca agctactgat gagaaaattt gttcagcgtt taataaaata gaacaaattc
   931681 gagaaaaaac atcgctcact tattttgaat tttcaacact agctgctctg attatttttg
   931741 agctagaaaa agttgatgta gctgtattag aagtaggaat aggtggtcgg cttgattcag
   931801 ttaatattgt tgataataac gttggtgtta ttactaatat tgacattgat catgtagatt
   931861 atttaggtaa tactcgtgaa ttaattgggt atgaaaaagc aggtattatg cgaaaaaata
   931921 caccttgtat ttgtgctgat attaatccac ctacttcaat taatcaatat gctcatcaaa
   931981 tcaaggcgca actagaattt gtaaaacaaa gatacacagg tgatattggc ctaatcagta
   932041 agcatcaaca acaaaatgca gcaacagcaa tacttactgt acaaaaattg aataagacgt
   932101 taccaataaa tgctaatgaa attaaaagag gcattaaata tgtgaaactt aatgccagat
   932161 tccaaataga aaccattcat aataaaacct ttatttttga tgttgcacac aatgtagctg
   932221 ccgttaaagt attatcagca gaactagcaa agcaaaaatg tcctaccatt gctatatttt
   932281 cagctttaaa ggataaaaac attggtttga tgattaataa aattagtatg gttataaatc
   932341 aatggctgtt agtaccactt aatgttaacc gggcaataag tatgcaaaca cttagcaaac
   932401 aatttaattt agctcataat atccaaattt gcaatgatat gcaagacgct attaatcacg
   932461 gcattaatga caaacaatat cggcgtattg ttatttttgg ctcattttat gttgtagcta
   932521 atgcattgaa aatacttaca ccatttatga aaaataataa agaataaatc ttgtaaaatt
   932581 acaactaatc acatagtatc tctaggagaa atttgatgaa cgagtttttt ataactattt
   932641 ggaacatgat tgaacgctta gtttggtcag attggataac cattgctatt ttagcgatat
   932701 tcctagtact aggatttaag cgtggcctag caaaagaact gattaattta ggttttctat
   932761 tactagcaat tttaattaca ttgttgtttt accaagtatt agctacaagt tcacttataa
   932821 cttggctaat gctatcacat caatctcatt taactatctc attttggata atttttattt
   932881 gtattgtaat tatcaaaaaa ttaatttaca aactaacaca actttcttta accattaata
   932941 acccttgtgt gctaaacaaa ctatttgcac taatggttct tttcacagca attacaatat
   933001 ttagctgtca tcacctagat attgtagctg gattagatat tatagaagta tttattgata
   933061 ataaatacat tcgtataagt gtatcattta ttattttatt tagttctatt tttggtattt
   933121 ttacttttat atcaaaaata ttaaacattt ctattgacaa aacaaaacct tgtttcttat
   933181 catctttttt cgagaaaata cttaaaattt tacaagcaat ggacattaag cttaatgcaa
   933241 gaaatattaa cagcacccaa aacagtatat taggttcaat gatgggcttg attaaagcca
   933301 acttagcaat tttaatcata gtgttaatgt tacaaaatat cagctgggtt tcacaacaat
   933361 attattggat tgaaacaaat ggtgctttaa gaatatttca agatatagcc tcaaatatca
   933421 aacctgtatt gtcacaatac ttgctgttta ttaacaataa ttaaggatta atgtatgtgt
   933481 ggtattgttg gtattttatc tactactaaa aaagatatag ctgtttatat ttatgatgcg
   933541 ttaactattc tacaacaccg tggtcaagat gcagcaggta ttgtaactgc ctataaagga
   933601 cgtttttata tgcgtaaatc aaacggccta gttaaaaacg tctttagaac taaacacatg
   933661 acacaattat taggtaatat gggcattgga catgtgcgtt atcctacttc aggaagctca
   933721 tccaatgcag aagtgcaacc tttctatgtt aactctccat atggcattac atttgcacat
   933781 aacggtaatc taactaatac tgaacagtta tctcaagaat tatttgaaca agaccttcgc
   933841 catattaaca ctaattctga ttcagaaatt ttactgaatg tatttgccag tgaattagct
   933901 aaactacaaa aacaacgtat taacgaatct gatattttta actctgtctc gcaagtacac
   933961 aaacgtgtac gaggtgctta tgcagctatt ggcatgattc caggatatgg tatttttggc
   934021 tttagagacc caaatggcat tcgtccactt attcttggca aatgcatcac caaaggtggt
   934081 actaaatata tgttagcctc tgaaagtgta gcacttagag cactaggtta taaaattact
   934141 caagatataa aaccaggtga agcagtcgtt attgatagaa ttggtaatat atttattaaa
   934201 caatgcacag aaaaagcaaa atactcaccc tgtatctttg aatttgtcta ttttgctcgt
   934261 ccagattcag taattgataa tatttcagta tataaatctc gtttaagaat gggggaaaaa
   934321 ttagccgaaa aaattaataa agaatggaac attgataaca ttgatgttat tatccctatc
   934381 cctgacacct ctagagtagc tgctttacaa ctagcacata aattagacgt taaatacagt
   934441 gaaggattaa tcagaaatag atatattgct cgtacattta tcatgccagg acaaaaactt
   934501 cgcaaaaaat cagtacgcca aaaactcagc acaattgaac ttgagttcaa gaacaaaaat
   934561 gtattattgg tcgatgattc tattgtacgt ggcacaacca gtgagcaaat tgtacaaatg
   934621 gctcgtgacg ctggcgctaa taaggtattt tttgcctcag ccgcacctgt tgtacgttat
   934681 ccaaatgtat atggtattga tatggcaagt aataaagagt ttattgccca caatagaaat
   934741 atcgatcaaa tctgcaaagc tatcggtgca gacaagttaa tctatcaaga tttagacgat
   934801 ttaatctggt gcgtacaaca agggaataac gcaattacca catttgattg ctcttgtttt
   934861 aatggtcaat acgtgaccaa cgatattgat caagactatc ttgaacatat tgaattttta
   934921 cggggcaact ccactaaaaa aaataacaat acctgtgaag cttctgaatt aattggtaat
   934981 gatgtagaat agagttattt aacaaattta aaaacacatg aaagacttaa gctttaatac
   935041 taaagccata cgcacaggtt ataaaactac tactgaacaa gaacattctg aggcaatatt
   935101 tttaacttct agttttgttt ttagctcagc tgaacaagct gccaatcgct tttctaaaaa
   935161 agatccagga aatatttatg cacgttttac caatcctaca gttgatgcct ttgaaaaaaa
   935221 attagctata cttgaaggtg cacaagcatg tgttgcaact tcatctggta tggcagcaat
   935281 ctttgcaacc attatggcac tgtttaaatc aggtgatcat attgttgctt cacgcaatat
   935341 gtttggcacc tcaattataa tgctaaatac aattattact aaatttaata ttgacattag
   935401 ttttgtcaat ctatctgact tatcagcttg ggaaaataca ctcaaaaata acaccaagct
   935461 tttcttactt gaaacaccat ctaacccgtt aggcgaggtt gtgaatatta acgcacttag
   935521 cagaatatca aaagccaata gtattctgct agcagttgat aatacaattc taagccctgc
   935581 actacaaacc cctattactt taggtgctga tattgttata cactcagcta ctaaatatat
   935641 tgatggtcaa ggtagatgtt tagcaggtgt tatagctgga agtactgata ttattgaaca
   935701 aattcataga tttttacgca ccacaggtcc tagtttaagc gcctttaatg cttggattgt
   935761 acttaaaggg ctagacacct taagtcttag aatgaaggca cattcggaca atgcgctcaa
   935821 acttgctatt tggcttgaag cccaagatca agtagaaaaa gtctattatt taggtttacc
   935881 ctcccaccct gatcacaact tggccaaatc ccagcaatct ggctttggtg gtatcgtatc
   935941 gtttaaaatt aaaggcggaa aaaaatcggc atttaaaata attaacgcta ctaatatact
   936001 ttctattact gctaatttag gtgatacaaa atctaccatc actcatccag cgacaacaac
   936061 acacggacgt ttaacagatg aagaaagact taacgctcat ataacagatg gattaatcag
   936121 aatatctgtt ggtctagaag acattaagga catcattgct gatattaagc agacactggt
   936181 ataatctaga taattgtttt acataaaaca caatgcaaaa ttctttctct tataatgagt
   936241 taattaaatg tggcgatggc gaattgtttg gattaggtaa tgcccaactg ccaaagcccc
   936301 ctatgttaat gtttgatcgt attagtcata tttctaatga tggaggcgaa tacggcaaag
   936361 gtgaaattat tgctgaatta gatattaatc ctaatctatg gtttttcaaa tgtcatttta
   936421 atgaagaccc agttatgcct ggttgcttag ggctagatgc aatgtggcaa ttaattggtt
   936481 tttatcttgg atggttaggg gggcctggcc gtggtcgtgc acttggtgct ggtaatatta
   936541 aatttgttgg acaagtgctt cccagtgcaa aaaaagtaac ctataagata gacttatcac
   936601 gcgttattgc acgtaaattg tatatgggtg tagccgacgc aaccatggaa gtcgatagca
   936661 aggtgattta cgaggctaca aaccttaaag ttggattatt tactgatact agcaaaatgt
   936721 aatgcataga gttgttgtca caggaatggg agttgtttcc agtttaggtg taaattgtgc
   936781 agaggttcta aactccttaa aaacctctaa atcaggtatt aaatttaata aaacccagga
   936841 aaatataggg cttcgttcac acctatctgg aacaatttct gagataaatt cagacgaaat
   936901 tattgataga aagatgaaac gctttatggc tgatgccgcc atttacaatg cagttgcact
   936961 agacgaagca attaaacaat caggcttaac aaaagtacaa atatcaaatg aacgtactgg
   937021 acttattatg ggttctggtg gagccagtaa ccaaaatata gttgaagcta ctgatatatt
   937081 acgaaaaaaa ggcattaaac gtgttggccc ttatcgtgta ccgcgtacga tgggctctac
   937141 aacctcagct tgtctttcaa ctctattcaa aattaaaggc attaactatt caatcagttc
   937201 tgcctgttca acatctgcac actgtattgg aaatgccatg gaacaaatac aaatgggcaa
   937261 acaagacgtg gtatttgctg gtggtggtga ggaactagat tggtcattaa ccatgttatt
   937321 cgatgcaatg ggtgctttat cttctaaata taataaattc cctgaacaag cctctcgtgc
   937381 ttttgacaaa ggacgagatg gctttataat ttctgggggt gggggtgctt tggcgcttga
   937441 atcactagaa tacgcacaag ctcgaggcgc aactattctt gcagaattaa caggatatgg
   937501 cgcaacgtcc gatggttatg atatggttgt gccatctggt gatggtgcta aacgttgtat
   937561 ggaaattgct atatcaacag taaatggacc tattaactac atcaatgctc acggtacctc
   937621 aacaccaatt ggcgatataa aagaactaaa tgctatcaaa gaagtctttg gcgataatat
   937681 tcctaatatt agctcaacta aatcactttc aggccatgca ctaggtgcag caggtgtgaa
   937741 tgaatcaatt tactcattac tgatgttgca aaataatttt atgacaaagt ctgtaaatat
   937801 caatatacta gatgaggcag ctaaaggcat gccgattata caaacaacaa taaaacaaac
   937861 atttaaccga gttatgtcga atagttttgg ttttggtggt acaaatgctt gtttagtctt
   937921 cgaaaaattt aaataataaa ttttaaaata tcacgcaaga atcaactctt atctaatatt
   937981 gtaggaattc aacgaaaaaa taaaataatt tttctcataa caacaaaata tatgagatta
   938041 ctaacgacta tttaataaat aaacatataa tatatgttta tattctctta tatatagcac
   938101 gtacattata taattctata gaaaaattta gttgattcaa aataatattc tttcctgata
   938161 atcatcatta ttattaatag caaaaataaa aactgactac tactaaaatt aatactacct
   938221 tgtctccatt aatttaaaaa acacattaat aaaaccaatc atagttagga taaaaataaa
   938281 aaacacagta attagattag aatttatact atattttatt tcaaataaaa ctgtataatt
   938341 cacgtttctt tacatgttag actttgattt aattaaatta aggtctagac tttgatttat
   938401 cagatgaaaa caaattttcc tttgtaatac ctaattcaag aatcatcaaa cttgcaacat
   938461 aaatagaaga ataagtgcca attactacac caattagtaa tgctaaagaa aaattatgaa
   938521 taatctcacc gcctaaaaag aacagtgcca ataataccaa taaagtagtc aaagaggtcg
   938581 ttattgttct agataatgtt tggttaagtg catcattaat aatcctagag gattcaacat
   938641 ggtgtgttaa caagaaattc tcacgaattc gatcaaacac cacaatagta tcattcaaag
   938701 agtaaccaat aactgctaat atagcagcca gtaccgtcaa atcaaactcg atttgaaata
   938761 atgaaaaaac acctaaaatg atgataacat catgaataag agctgcaatt gagcccaatg
   938821 aaaaacgata ttcaaaacga aataacacat aaatcaaaat accaatcagg gcatataaca
   938881 ttgctagacc accatcattt gtaagctctt cacccacctt aggacccaca aattcaaccc
   938941 gacgaatatc aacatcatca cccaataaat aaataatttt tgaacttagc ttagcattag
   939001 aaattaattg aggttctaaa cgaattaaaa tttcattggt tgaaccaaaa tattgaacat
   939061 tagccctttt aaaatttgca ttcaccaaaa tagctctaat ctcagctaaa tcaacacttt
   939121 gttgatatcc tacttcaatt aaagtacccc ctttaaaatc aatgcctaat ttaagtcctt
   939181 ttgtagttaa tgaaaaaata ctaactgaaa tcaataacac tgaaaatata atggcataag
   939241 tacgcttacc tataaagtta attgttggaa tatttaatac tttaaaactc atattgaaat
   939301 ctcttctaac ttcttaccac tatatatctt attaataatt gcacgtgaaa caataatagc
   939361 tgtaaacatt gaagtaataa taccaattga caaagtaatc gcaaaacctt taattactcc
   939421 agtaccaaaa ctaaataaaa tcaatgccgc aatcaaagtc gtaatattag catctaaaat
   939481 agtcaatagc gccttatcat aaccgactga aatagctttt ggtaaatttc tatttattac
   939541 catctcttct ttaatacgtt caaagattaa cacattagca tcaactgcca tacctactgt
   939601 taacacaata cctgcaatac ctggcagtgt aagagtagct tgtaataaag acaaaataga
   939661 taaaatcatc actaaattaa gcgtcaaagc cacatttgct accataccaa atagttgata
   939721 acgcatagcc ataaacaata acactaaaat aaatccaact aatattgata taactccttt
   939781 agtgatatta tctgaaccaa gacttggacc aatagtacgc tcttcaataa tttcaatcgg
   939841 cgctgaaaga gaaccagccc ttaataataa cgctaaatta cgcgcctctt tgatattatc
   939901 aatacctgta acctgaaacc gtgacgaaaa tataccttta attgtagcag cattaataat
   939961 atctctagta gtggtacgct tcttaatggt tttaccattt ttaacaattg tttcaacttt
   940021 attctcaata aaaacaactg ccatacgatg gtgcaggtat tttttagtgg tattaaacat
   940081 tgccctaccg ccagcactat caagtgtgat attaaccatt ggcgtgttat tttcttggtg
   940141 aacaccagac gttgcaccag taatattttc acccgttgta atcacatgac tttttagcaa
   940201 aagcggacga ccatctttaa aataataaag ttttgagcca attggtaaac gccctgactg
   940261 aatagctatt tgtgggtcat ttttttcatc aactagtcta aattctaaag ttgctaccgc
   940321 acctaaaatt tcttttgctc tagccgtatc ttgtacacct ggtagttgga ctacaatacg
   940381 ttccaggcct tgctgttgaa taattggctc tgctacacct aactcattca ctcgattacg
   940441 taacgttgta atattttgtt taagtgcact tttcttagct tgtttttgta cactctcact
   940501 aataccaata tttagtaata aatcatctgt attactcagc agaactaaat cactcaattc
   940561 tgatttaatt aactgggatg cctcgtcttt taattcagat cgcttaaaat gaataacaat
   940621 actattacct ttttgcttta tgcttttata tagcctatct ttacgtaata aaacacgaag
   940681 ttcattgtat gctgtatcca ttgaagctga aattaccgct ttcatatcaa cttctaataa
   940741 aaaatgaaca ccacctctca ggtctaagcc aagtgacata gccttaccac caagacttgc
   940801 caaccaaact ggtacagaag gtgccaaatt taacgccacc acgtaactcc ggctcagtgc
   940861 cttattaaga gcatctttag ctaaaagctg ttgcatctta ttcttaaaac gtactaagat
   940921 tctttgatta attaattcaa tagatttaaa cttaatttgt tgaatcttta atacattttt
   940981 aattttaacc aaatcctgat caacaattaa agcattatct acacttgata cttgaatagc
   941041 taaatcagaa ccaaatatat ttggtaatgc atacaatatt gaaagcaata aaacaaatac
   941101 aatcaatgca tttttatgcc atgaataatg attcataatg attataatta attaaatttt
   941161 agcgctccct tttggcattt tttgattaat accttgcttt tgtaccttaa ccaaaatacc
   941221 attagcaatt tctaatattg caaaagactc atctacagaa acaactttac caattatacc
   941281 gccattagta acaacctcat cacctgtttt taatgctact aataatgttt tatgctcctt
   941341 ggcacgtttt tgctgaggcc taatcagtaa aaaatacatc aacgcaaaca taaccaataa
   941401 aaatggtaac ccactccatg aatctagaat actactctct gatactaaac cttctgcgaa
   941461 tactggtaca ataattaaat ctaataaatt cattttatct ccttatataa aaaattaatt
   941521 cataacttcc aaaccaccca tataactctg taaaacaaat ggtattttaa tacttctatc
   941581 agcttgctga tgattttcca aaaccgccac taaagttcta ccaactgcta atcctgagcc
   941641 atttaatgtg tgtaataatt ctaatttatt agtttctttg tttttatacc ttaattgcaa
   941701 acgtcgtgcc tgaaagtctt caaaacaaga acaagaagaa atttcacaat aaacattttg
   941761 tccaggtagc cacacttcta aatcataggt tttagtagca gaaaaaccaa ggtctcctgc
   941821 acataagcta atttttctat aaggcaattc taatgcttgt aagatatctt cagcatgtgt
   941881 agttaatact tctaaagctt ggtacgaatc ttgtgcttta actacctgta ctaactcaac
   941941 tttttcaaat tggtgttgac gaataaggcc gcgagtatat cgtccataac tacctgcttc
   942001 tgatctaaaa ctaggtgtat gagtcacaaa tttaagaggt aaatcattct cttttataat
   942061 catatcacgc atcatattag tcacgggcac ttcaccagtt ggaattagat acaatgtctt
   942121 tgtttccccc ttctcaccat gcaaatatgt tttaaataaa tcagcttcaa actttggcaa
   942181 ctgacctgtg ccaattaagg attctgtatt cactaaataa ggcacataag cctcagtata
   942241 gccattaact tcactatgtc gatctaacat aaattgtgtc aatgcacgat gcaaacgtgc
   942301 aattttccca gtcataacag aaaatctagc accagaaatc ttaactgctg tctcaaaatc
   942361 tagtccatac atcgcaccca aatcaacatg gtcttttaca tcaaaatcat aattaactaa
   942421 tttaccccat tttgatacct caatattatc ttcttcactt ttaccattag gtacagaatg
   942481 atgaggaata ttaggcatcg ataaaacaat tacatcaatc tcagattgaa tcaattgtaa
   942541 atttgatttt gccaaattca acttagtact taaatctgaa acattcttta ataaagactt
   942601 aatgtcttcg ccagaagctt tagcttttcc aatcgcctta gactgcatat ttcgtagatt
   942661 ttgcaaattc tgagtttcaa tttgattttt ttttctatta ctttctaact caattaaatg
   942721 atcaacatca aaataaaaat atcgcttctt taaggcatta gcaacagctt tcatgtctaa
   942781 tctaagttgt tttttactta acattgttat ataataattt tattatatat attatatgcc
   942841 taaatacacc aggtctaact ttaaaaacta actttggaaa ttatactatg tttaattcat
   942901 tttcaagcaa tgatgcttgc caactattag ctaacggcgc tcaattagtt gatgtccgtt
   942961 ccagtaatga attcgctcaa ggcgcactgc caaatgcaat caacctacca ttacagtcta
   943021 ttatgactgc tgatagaatc attgaccgta ataaggctgt tattctttat tgtgttacag
   943081 gtatacgttc atcaactgct aaaaattatt taatacaaat gggttataaa aatgttaacg
   943141 atttaggctc atttaaaaat tacaactgcg aataacacaa tacaataaca atggtataaa
   943201 cttatacaat gagagttaaa agcacttggc acaaaactca agtaaaaacc attgatgata
   943261 ttgctagcac actagcattt aattcatggc gtattactaa aaatcatcta gaagatttaa
   943321 ttaacgaagc attcataatt gaaaaagcac aagtgtttga tgtaatctct gaatacttat
   943381 actttttaat tcaatgtatt gataggttgg ttcttgataa attaaattat aaacagcgtc
   943441 aaacattaat tatcaaactt gctaagcaat cagctactta ttttcatgaa aacaaacaag
   943501 aacgtattgg ctcaggagaa tattggaatg actttattca aacttataac aacaggtcta
   943561 aaaactacgc caattatgaa tttacaaatg gtgagcctag ttatcatttc ttaagatact
   943621 ttgcaaagaa aatacaaaaa gctatgacta atgctgattc aaaatggatt gtccaacaaa
   943681 ttattgaaat tcaagcacca aaggccttta aatcaataaa aagaagtatt aaaaatttga
   943741 tagcagttga aaaaataata ttcaaggccg aacaaataaa aaataaaaac aagatcccta
   943801 gatccaaacg aaaatcaatt tttcctaaat tacaataaac tcataaactc aactcactca
   943861 taataatatt aagaaatagg agctaatatg attgcaatat gcctaaactg taatagactt
   943921 aacaacattc caaaaaacaa attaaaaaac aaacctaatt gtggtaactg caaaaatcca
   943981 atatatagcg gtcaacctat taatgtaagt ggtatacagc ttactcgtgc aatagaaaaa
   944041 actgatgaat tattggtggt tgatttttgg gcaacctggt gtggtccctg caaaacattt
   944101 gctcctactt ttaaacaagt gacaacacaa cttgaaccta aggccagatt tatcaaaatt
   944161 gaaactgaaa aagaacaagt aatttctact aaacacaata ttcgctctat tccaacatta
   944221 gccattttta aagatggtaa agaaatagaa cgcatttctg gttcactaag tgccccagat
   944281 tttattaatt gggttaatca atatacataa taaggatctc ctaaacataa aatttgtcta
   944341 ggagctttaa atttaaagcc tagcaatgtc ctactctcac atggggagtc cccacactac
   944401 catcggcgct aagtggtttc acttctgagt tcggtatggg atcaggtggg tcacactcgc
   944461 tattgtcact aagcaaactg gttgtataat tgtgtataaa tcacaattat aattaactaa
   944521 aaagttttta taccttaact ataaactata tagttagaag ttataacaat caaatacatt
   944581 tataaagttt atattattat tagcgtatta catgacacat caaacacaaa aattacagat
   944641 tcatttaaat aatttgggtg ttatatggtc aagcctcacg atcaattagt acaggttagc
   944701 ttcacacgtc accgtgcttc tacaccctgc ctatcaacct cgtagtcttc gagggatctt
   944761 taggagtgtt taaacactca gggagaccta atcttgggag aggcttcccg cttagatgct
   944821 ttcagcggtt atcctttcca cacatagcta ctcggcaatg cgactggcgt cacaaccgaa
   944881 acaccagagg tgtgtccatt ccggtcctct cgtactaaga acagcttccc tcaagtctcc
   944941 aacgcccacg gtagataggg accgaactgt ctcacgacgt tctaaaccca gctcgcgtac
   945001 cactttaaat ggcgaacagc catacccttg ggacctactt cagccccagg atgtgatgag
   945061 ccgacatcga ggtgccaaac accgccgtcg atgtgaactc ttgggcggta tcagcctgtt
   945121 atccccggcg taccttttat ccgttgagcg atggtccttc cactcagaac caccggatca
   945181 ctaagaccta gtttcctacc tgctcgacgt gtcagtctcg cagtcaagca cccttttacc
   945241 tttgcgctca ttgcacgatg tccgaccgtg ctgagggtac ctttgcgctc ctccgttact
   945301 ctttaggagg agaccgcccc agtcaaacta cccaccatgc attgtccctg atccagataa
   945361 tggatctagg ttagaattcc aaccatacta gggtggtatt tcaaggatgg ctccactcaa
   945421 gactagcgtc taagtttcaa agcctaccac ctatcctaca caagtaggat caaaattcaa
   945481 tgcaaagctg tagtaaaggt gcacggggtc tttccgtctg gccgcgggta tactgcatct
   945541 taacagcaat ttcaatttca ctgagtctcg ggtagagaca gtgtagccct cgttacgcca
   945601 ttcgtgcagg tcggaactta cccgacaagg aatttcgcta ccttaggacc gttatagtta
   945661 cggccgccgt ttacttgggc ttcgatcaaa agcttcggat aaatcctaac ctcatcaatt
   945721 aaccttcaag caccgggcag gcgtcacacc ctatacgtcc acttacgtgt ttgcagagtg
   945781 ctgtgttttt aataaacagt cggagctacc tggtatcttc aactcttacc agcttcattc
   945841 agcaagtaaa attaccggca agagcacacc ttctcccgaa gttacggtgt cattttgcct
   945901 agttccttca cccgagttct ctcaagcgcc ttagaattct catctcgtcc acctgtgtcg
   945961 gtttggggta cggtttcata taacctgaag cttagaggat tttcctggaa gcatggtatt
   946021 acgcacttct cccaaaagag ggatcgttat cacgccttaa aatatagagt tccggatttt
   946081 cctaaaactc atttctacac gcttgaactt ggacaaccat agccaagctg cgctaacctt
   946141 ctccgtcttc ccatcgcagt tatatgaagt ataggaatat taacctattt cccatcgact
   946201 acgcatttct gcctcgcctt aggggccgac taaccctacg ccgattaacg ttgcgtagga
   946261 aaccttggac ttctggcgag ggggtttttc acccccttta tcgttactca tgtcagcatt
   946321 cgcacttctg atacctccag taaaccttac aatttacctt caacggctta cagaacgctc
   946381 tcctaccatt gcaataaatt gcaatccgta gcttcggtat gtagttttag ccccgttaaa
   946441 tcttccgcgc aaaccgactc gaccagtgag ctattacgca ctctttaaag gaatggctgc
   946501 ttctaagcca acttcctggc tgtcttggcc ttttcacatc gtttcccact taactacaat
   946561 tttgggacct tagctgacgg tctgggttgt ttccctttcc actacggacg ttagcacccg
   946621 cagtgtgtct cccatgctca tacttgtcgg tattcggagt ttgcaatggc ttactaagcc
   946681 ttgacgaccc gctaaccata acagtgctct acccccgaca gtaatacatg aggctctacc
   946741 taaatagatt tcggagagaa ccagctatct ccgggtttgt ttggcctttc acccctatcc
   946801 acagctcatc ccctcatttt tcaacataag tgggttcggg cctccagtta gttttaccta
   946861 accttcaccc tggccatgga tagatcaccc ggtttcgggt ctactcccag caactaaacg
   946921 cccatttaag actcggtttc cctacggctc ccctatttgg ttaaccttgc tactgagaag
   946981 taagtcgctg acccattata caaaaggtac gcagtcacag aataaatctg ctcctactgc
   947041 ttgtatgcat acgatttcag gttctatttc actcccctcc cggggttctt ttcgcctttc
   947101 cctcacggta cttgttcact atcggtcatt agagagtatt tagccttgga gggtggtccc
   947161 cccatattca aacagcgttt cacgtgcgcc gctttactcg atttaacata aattaaactt
   947221 tcctatacgg gattatcacc ctgtatcatt gaactttcca gaacattcta gtaatttaaa
   947281 atatgcttaa gggctggtcc ccgttcgctc gctgctacta agggaatctc ggttgattta
   947341 ttttcctcta ggtacttaga tgtttcagtt ccctaggttc gcttccttaa cctattctat
   947401 tcaattaagg ataatggtct gatgaccact gggttttccc attcggagat cttcggatta
   947461 aagcttattt atcagctaac cgaagcttat cgcagattat cacgtccttc atcgccttct
   947521 aatgccaagg cattcatcat atgcacttat ttacttgact atataacccc aaattatcta
   947581 ttatgtttta tctatttact gtataaattt tttgcttaat caactattta gcaaagctaa
   947641 acctattaat cactcaagga aatgctttac aaataaataa aattcaaaac cttataatat
   947701 tggtgtttat agttagtatt tcaccttgaa ttcacaaatt atgataaatc acaattagtg
   947761 aattcttttt atttcattga gataaattaa tatctcaatg agaatccata tttttttgaa
   947821 attgttgtgt caatgcaata caccaatgaa gactattatg ataataatct tcgcgttgtt
   947881 atattgtata tttacaaact ttacttcatg tattaaattg ttaaagagct ctacactcga
   947941 aggtgcagta taaaaactta aacaaaacaa caattaaaat ttttttgttt aagttttctt
   948001 ttgcacaata aacagaatac ttggtggagc cagggaggat cgaactcccg acctcttgcg
   948061 tgcaaggcaa gcgctctccc agctgagcta tggcccctta cttacagcat aaaactgtag
   948121 gttttttaca aaagggactt aattgaactt acgtaataaa cgatgggcct gaagtaatca
   948181 taacgcaaaa tttggtgggt ctggatggat ttgaaccgcc gacctcaccc ttatcagggg
   948241 tgcgctctaa ccaactgagc tacagaccca aaattatttg tctattttta ttattttatg
   948301 caatcatcat aaaaattacc tcacattagt gtgatgcaat tcttattatc tttatcatta
   948361 ttaaacaact tgttgtggac actcatactt ttcttaagga ggtgatccag cctcaccttc
   948421 cggtaaggct accttgttac gactttaccc cagtcatgaa tcacaccgtg gtaaccgtcc
   948481 tctataaaat agttaaacta gctacttctg gtgcaaccca ctcccatggt atgacgggcg
   948541 gtgtgtacaa gacccgggaa cgtattcacc gtagcattct gatctacgat tactagcgat
   948601 tccgacttca cggagtcgag ttgcagactc cgatccggac tacgaaaaga tttgtgagat
   948661 tagcaccacc tcacggctta gcgacccttt gtccttccca ttgtagcacg tgtgtagccc
   948721 tggtcgtaag ggccatgatg acttgacgtc gtccccgcct tcctccggtt tatcaccggc
   948781 agtctcctta tagttcccac cattatgtac tggcaaataa ggataagggt tgcgctcgtt
   948841 acgggactta acccaacatc tcacgacacg agctgacgac agccatgcag cacctgtatt
   948901 cgcattcccg aaggcaccaa tctatctcta gaaagtttgc gatatgtcaa gaccaggtaa
   948961 ggttcttcgc gttgcatcga attaaaccac atgctccacc gcttgtgcgg gtccccgtca
   949021 attcctttga gttttaacct tgcggccgta ctccccaggc ggataactta acgcgttagc
   949081 ttcgccacta aagggtaccc cccccaacgg ctagttatca tcgtttacgg catggactac
   949141 cagggtatct aatcctgttt gctacccacg ctttcgtacc tcagtgtcag tattagtcca
   949201 gaaagctgcc ttcgccattg atgttccttc tgatatctac gcatttcacc gctacaccag
   949261 aaattccact ttcctctcct atactctagt tttccagttt caaatgcagt tcctaggtta
   949321 agcccagggc tttcacatct gacttaataa accacctacg cacgctttac gcccagtaat
   949381 tccgattaac gcttgcaccc tccgtattac cgcggctgct ggcacggagt tagccggtgc
   949441 ttcttctaaa agtaacgtca aaaataatag atattaacca ttattttttc ttcctaattg
   949501 aaagtgcttt acaaccctca ggccttcttc acacacgcgg tattgctgga tcaggcttgc
   949561 gcccattgtc caatattccc cactgctgcc tcccgtagga gtctggaccg tgtctcagtt
   949621 ccagtgtggc tgatcatcct ctcagaccag ctaaagatcg tcaccttggt gagcttttac
   949681 ctcaccaact agctaatctt acgcaggctc atttgatagc gaaagcatat ataaccagag
   949741 gccttcttta ctttatcaag attatgcggt attaatccgg atttctccgg gctatccccc
   949801 actatcaagc agattcctac gcgttactca cccgtccgcc actcgacacc tactagcaag
   949861 ctagtatcgt ttccgttcga cttgcatgtg ttaagcatac cgccagcgtt caatctgagc
   949921 caggatcaaa ctcttcagtt caattctaac catttagaac atctaaaaca attcaaataa
   949981 ataaatatgc tttatgttca atttttttaa aagcttattt gctttagttt ttaatgtgca
   950041 cttgcacaat ttattgtacg agtgcccaca caagttgttt aatatatttt taaagagcaa
   950101 ctacaacatt aaattgataa agtaattttt tgctacagtt aagaacaaaa aattatacag
   950161 ctaatagcta atctgtcaag tattattttt aactttatac ttccaaatcc ttatttcatt
   950221 aaaaatgaag accattttca tataatatta caaatgataa tgaaattaaa tattaattag
   950281 cattattttt gcgagattct aacttatctt ctgaaatcgc tctattaagc caagcatcag
   950341 ctttattaat atcaacaatt acatgattgg aattcaccat ttcaagatca ttatcattcc
   950401 aacctttaat acccattttt aatgaacgaa ccttattaaa gcccatttgt tgcatagtca
   950461 aagttgcgag tgcactacga ttacctgaat gacaaataac aataatatct tggtttattg
   950521 cttgtactaa ttttggcaca gtattatcat aattccaaac acatgcactc tcaagtatac
   950581 ctctaggaac atgaattgaa tttttaatat gcatcatatc aaattcatct tgctcacgaa
   950641 tatctaataa tattagatct ttatttcttt gaatctcttc ttccaagtcc cacgaaaata
   950701 tctcaatcac tgatgataat gcttgtgcta ctaatttttg atatctatcc attaatttta
   950761 tttgcaataa cctttttgtg tcaccattac tgctacttca acgcgtgagc ttagtgataa
   950821 ttttttaaga attgacttga catgtagttt aactgtacca tcagaaatac ccagttctct
   950881 ggcaatgact ttattactat aaccactaga tacttggcaa gcaacttctt tttctcggct
   950941 agttaaggag ccaaatgaag gctcattgtc ggttaattca tcccgtaaag cctttgctag
   951001 tatatatctc atatcttgtg caacaacaat tgaaccttta ataacttcat ctagagcatc
   951061 gactagttca tctggatcca tgtcttttaa taaataacct tgtgcgccat gtttaagaca
   951121 actacgtaaa tcatactctt gggtactagt agttaacatc acaattggta tggtaatatt
   951181 ctttgttttg agtattttta acacttcaag tccagacatt tgaggcatac gtaaatctaa
   951241 cagaataata tctactgaca aagaagggat ttctatcaaa ccttgctttg gcgaagcagc
   951301 agcactggca ctaatttgtt tagattccaa taaagcaata agtccattac gaaacaaggc
   951361 atgatcatca ataatgtata ttttcatgat accttctgga aattgactat aacacgtgta
   951421 cttccatcaa cttctgattc gattttaata ttagcaccaa ttcttatcgc tcgttctttc
   951481 ataatattca taccaatatt atttcccatt acttcacttt tattttggtc tttttcaaat
   951541 ccaacaccat catcttcaat taataattga caattaggtt ctgccaaaag taaaacacgt
   951601 acattacgag ctttagcatg tttacgtata ttagacaatg cttcttgggt aatgcgcata
   951661 atttgcattt ctacttccgg agatacttgt aatttaccct caacctgtaa ataagtagta
   951721 ataccttctt ctgacataaa tcgattaagt aaagttgtca aagaagcctt aattccttta
   951781 ggatctaacg gtatgcgaaa attacacata agttcacgta actcttgatt tgcttgagta
   951841 atattagatt gcaaactcag cactttatcg tttgcatcag attttttacc tactttaagt
   951901 atgtttccaa gtgccgttac ttgtaacttc aaactataaa tagtttgtgc taatgagtca
   951961 tgtatttctt gtgataaaaa taaacgttct tgtgacaatt ccatgcgttt agtttggata
   952021 tccagccaag ctttatctaa tgaaatagca atattttcag caatagaact aagtagtaca
   952081 cgctcatcaa aagccaatga tggtaatgta tcaaaaaaca aattaaaggt acctagtgtt
   952141 tttccatgat acctaagtgg tatgaatatc gtaccaatac ttgctttagt tcgagatttc
   952201 ttacctacac attgtgcaca agtatgcacg ctaaattgta cacaagtatc acttgccata
   952261 gccacttcac cacaaaaaca atctgcgctt aatacgtcca ttacttgtcc tttcttatca
   952321 atcacgcctt gtgttgccat caaatgaagc tgactatcat cagataaact acgtgcagca
   952381 cctgatgaag caccagtcat cttaataaga atgtctaaaa agtgtgcaaa taattcatca
   952441 atcgaatgta ttttattaag ttttgatgac acactataca aagtttctaa agaggcagat
   952501 tttttactta aacgctgaac ttgtttattt aaaatactct ccatatcatc atataaacat
   952561 tgattttcat taattagatg attaatcgct tttgcaacag gctgaaacgt ggttttttga
   952621 tgatcactta aacgtacact ttgactaaac ttataaccat ctacccaact ttgcaagtca
   952681 ttaaatggca ataagaaatc ttgacgaata gacaagtata gacctaaata gaccaataaa
   952741 attaggacaa caagtaatat atcaactacg ctagtcattg tataagaaag catcgcttca
   952801 tacattaaca atggtgaaag caaaatcgtg actaaaaagt aaatataaaa tttagtttta
   952861 atattcatta ttttttagtt taaaaccaaa aaacaggctt ttcttatttt atttcccaat
   952921 acaaaaagaa gaaaatattt catcaagtaa atcatccgat gaaaattcac cagtaatact
   952981 acccataaat tgaccagcaa aacgtaaatc ttcagccatt aactctattg cgccaatttc
   953041 taattgcata atagcatttc caatagacac taatgatgcc tctagagcaa tgatatgacg
   953101 tcttctagca agaacaaccc cttctgataa atcttctaat cctgaaatat tagataactc
   953161 ttttcgtaat agttttatgc cttctgaata cttagctgaa actgacaatt gtacaatatc
   953221 attaatcact tctcttttaa tagcaccact cgttaaatcc accttattct taattaacaa
   953281 caaagattga tcattaatat ttttaggtag tatggataaa tctggtttat catcttgtgc
   953341 gtcaaatacc attaacacta catcagcatg ctcaatctca aaattcgctc tcttgatgcc
   953401 ttctttttct atcttatcat ggctattacg cagacctgct gtatcaataa tactaagtgg
   953461 tacaccattt acatgaatag tttctttcaa tacatcgcgc gttgtacctg caatatcagt
   953521 cacaatagca ctagattctt gtgtaagtgc atttagtaat gaagacttac cagcattggg
   953581 ctttccagca atagcaacat tcaaaccttc tcttaaaata ataccttgcg tggcagattt
   953641 taaaatagtt tcaattgtct gtttaatatc ttttatttta catttaactt gatcgaattg
   953701 caaaaaatca atttcctcat ccgaaaaatc tatagttgct tcaacaaaaa ctctaagctc
   953761 gataatagat ttggtaagtc catttatttg attagaaaaa tcacctgata aagatctaaa
   953821 tgctgactta gaggctcgtt ttgaattagc attaatcata tctgaaatcg cttctgcttg
   953881 tactaaatcc atttttccgt ttaaaaaaga acgcttcgag aattcacctg actcagctag
   953941 tttagcaccc attgatatgg cagattctag taaaaggcgc ataccaatca taccgccatg
   954001 tccttgaaat tctaatacat cttcacctgt aaatgaatat ggttttggga aaaacagagc
   954061 aatgccttta tctatttcag tgctttcttg gtcaaaaaat aaaccataat atgcatatcg
   954121 tggcttagga ataaacccaa gcattttttt tgcaataact ttacataatg gtcctgatac
   954181 acgcactata ccaatacccc ctttaccaac actactggct aatgcacaaa ttgttgtttt
   954241 actgctattc attaattttt aagatatttt ataaaatact catttagaaa tgtatcaaaa
   954301 tctactaaat cagaagcttc aatttgaagt tgcttttgac atgaaacctt tgcttgatga
   954361 tctaaataat cgaaatgttt cttgtttatt ttattaaata agaaatcgcc tctatatttc
   954421 ttagacaatg aattagtgta atcaaaaaaa ccctgattac gccttttcat ctgactaaga
   954481 gttatcgcag aaggtgttaa atctggattg ttaatacgac atgctatatc tcgaacagac
   954541 acttgatgat tttcacttaa taacgctgta caccattcca ttttagtgat aatatcagac
   954601 ccccactctt gacgtgaaat ctgtttacct ttgtacatta acattaattt aggcttacga
   954661 ccttcatggg caactagctg atcattagtg tcaattccaa actgttctga ggtagaaata
   954721 gcacaggatg gttcaagtaa acaaaacaac ataaacgctt ctaaaaaatg aatttgtggc
   954781 ttatcgatac ccaatgataa aagtggatta atatctattg accttaactc aacatagcca
   954841 ataccactat tacttagcgt atttagagaa tttttatttg actcaagtaa cggttttgga
   954901 cgtacagaag cataatactc attttcaatc tgtaaaatgt tagtattaag ctgctgatat
   954961 ttcccatgac gttttacacc aatcatttca tactcagaac aagaggtttg catgcctact
   955021 ttaagactgt ttatataatg actcaaactg ttgtaattag ctttaacacc tgcctcatcc
   955081 tcagctaaat tttgataacc aatatttccc atacgtaaag aggtagcata aggctcatac
   955141 agagttgaat cattaaattc aaccaacgaa tgcgtatggt acccttttaa aaatgactta
   955201 catacagcag gtgatgctcc aaataaataa ggaattatcc aaccataacg cactatatta
   955261 cggattagac ccatatagcc attatcaata aatgacctta gtacttctgt aggagcaaat
   955321 aatcttttat attgttgcca aaatttatta gaaaatgaat aattaaaatg aattcctgca
   955381 atagtttgca taacactacc gtaacgattt gctaatcctt gacgataaat tgttttcaac
   955441 tttccttggt tagaagttcc atattgagct ataggaatgg tagtttcacc acgaataacg
   955501 caaggcatac tagttggcca aaaattttga tctttaggta aatgatgata caaatagtac
   955561 tgagtatttt ctaaaaaaga taacatttct accgcaccac taagcggggg tgttaccaat
   955621 tctaataaag attcagaaaa atctgtggta atattaggat gcgttaaggc acagcctaaa
   955681 gcataaggat gtggtacttg agaaattcca cctttccttg atactcgcaa tccctctttt
   955741 tccaaaccca ttaaattacc tttcaatagt gtatcaaatg gttttaatcg ttgaattttt
   955801 tcctttaatt gcaaaacaaa tccagatgtt aaaatagcat tattttacat taggacaact
   955861 catgaaaaca atcaaggcag ttgtaggtat tttacataac aaaaaacaaa aaatactaat
   955921 tacaaaagca aaaaaaaata gttgataaac ggtttcttaa aattctttga tggcaaaatt
   955981 gaaactggtg aatcaaaaaa aaccatcatt agagaactaa aaaagagatg gacaaattaa
   956041 gcagctaact attcatacaa atataataca taagtatgaa gataaaactg tttagttaag
   956101 tatttataat ataaaaacct aatatacaaa tacatctttt tagtattgaa agttaaaaca
   956161 atatattaag ttgatattaa acaagcaatt agatgattat aaactattac ctgtcatgaa
   956221 aacatttatc aattctattg ctctacctga taaatattgg atcacaccat caaataacca
   956281 tcaaagtaat aaatggatgg aaaagtttaa ccaaaaacta acacaaaata taaaactcat
   956341 tcaacttaga agtaaaacca aaattaataa taactttatc caacaacttc acaacaaatg
   956401 taaacaacat aacatccaat tactacttaa taccgtcaat aaaactttta atgaggctta
   956461 ttgcgatggc tggaatctaa ctaccgctga aatgctaaaa tttaaaaaaa gaccttgcac
   956521 taacaataaa ctcttaggtg tatctacaca caacctaact gaagcactaa aagcccaaat
   956581 aataggtgct gactttgtta ttatctcccc agtacaagct acaaaaaccc atcctaaact
   956641 tctaccatta ggctgggata acgctaaaga agttgtcaat acactcaata ttcctgtcta
   956701 ttttttaggc ggaatgagac tccaagacct aaaaaaaact caacaacttg gtgcacaagg
   956761 tattgcaggc gtcagcactt tttagaagat taaaattgct gaaaaatata ttttaaatat
   956821 taaaaatcct caatatacat acataataca acttatcatg tatgtataag cattttacct
   956881 attgaatacg tgttctattt atactctttt aagtgctatt aacaactaat atgtatttcc
   956941 caaaaattct caataccaac cccaaaaata aaatcagtga ttattatgta ataatagaac
   957001 tatccctaat tttatattta tcaatactag tagtggatta attttgattt tttgaatgga
   957061 aaataataac taacattaaa taaaaattta aaacaaaaat taatcaataa ttctatctta
   957121 atatgatttc taaatgcacc actttcgtgg tgcatttaga aacattaata taatattttt
   957181 tacgttataa ttaaagggtt tttaaattta ttttatttta tagattataa cctatgaaaa
   957241 cccaattatt acacctgcct aaagctcgtg gtctttatca tccaaataat gaaaaagaga
   957301 actgtggcat aggatttatc gctcatatca aaggcaagcc ttcacaccaa attaccattg
   957361 atgccttgga aatgctatcc agaatggaac accggggtgg ttgcggttgt gaaaccaata
   957421 ctggtgatgg tgctggtatt ttaaccaata ttccacacaa atttttcatt caagaaatta
   957481 agcgtttatt tgatgtagta gttgaaaaag gtgcttatag cgttggtaat attttcttgc
   957541 cacaagataa aaaacaaaga gcacattgca tgaatttatt agaaaaatct attgtatgcg
   957601 agaatcaaac ttttattggc tggcgtaatg tacctattaa tattaataag gccaatattg
   957661 gtaatattgc tagaaaatct aaacctgtaa ttaaacaact cattattgct cgtgctaagg
   957721 ggattgacac accaactttt gagcgtgcat tatttattat tagaaaacac acctcaaaca
   957781 tcattagaac agataaggct ttatctcaag cattattatt ctatgtttgc agtatgtcaa
   957841 gtaatattat tatatacaaa ggcatgttgt taggatcaca agttcttgat ttttatcagg
   957901 atttatctga tattaaatat tcaacctatt tagcaatggt acactcacgt ttctcaacca
   957961 atacatttcc ttcatgggat agagcacaac cttgtcgcta tatgtcacat aatggtgaaa
   958021 tcaataccag acaaggtaat tataattgga tgcatgctag agaaggtgta ttgaaaagta
   958081 agctttttaa gaacaattta aacaagacct tacctgtaat tgaaactgaa gtttctgatt
   958141 ctggtagttt tgataatgta ttagaatttt tgatgatgaa tggtcgcacc ttacaagaat
   958201 cagcattaat gatggtacct gaggcctggc agaatgacag caatatgagc gctgaaaaaa
   958261 aagcatttta tgaatatctc tctaacatta tggaaccgtg ggatgggcct gcttctattg
   958321 cttttactga tggtttttat attggtgcaa tgcttgatcg taacggttta cgtccttcac
   958381 gctactacct gacccacgat gagcgtgtta tcatggcaag cgaagtaggt gtagttgatg
   958441 tagcaactga taatatcaaa actaaaggaa gattacgtcc aggaaaaatg tttttagttg
   958501 attttaacaa aggtgaattg gttaatgatg aaacaattaa atctgaattt gcagcaaaaa
   958561 atccttacca aacctggtta aatatccagc aaatacatct atcagaattt cactgtcaaa
   958621 ctgaggcgca tagcctccat ccagaatcat taattcatcg tctaaaaacg ttcggttata
   958681 gcacagagac cttacaattt atgttattac cactagttaa tgagttacgt gatccagtag
   958741 gatctatggg taatgattca gcactagctt gtttatctag ccaatctcgc attatttacg
   958801 attattttaa gcaattattt gcacaagtca ccaacccagc aattgactct attcgcgaag
   958861 aagtagtaat gtcattacgt tgttccattg gaccagaggg aaatttatta catgataagg
   958921 ctgaaaatgc gcaccgttta gttattgaac atccaatttt aactaataaa gaggttaccg
   958981 cattaaaaca ttgcaatcat cgtaactgga caagcaaaac cattgatatc acttatgata
   959041 ttaataaggg taaaaaaata tctgacttac tagatgatat ttgcaaccaa ggatctcaag
   959101 ccattaaaaa taaacacaat ttaattatat tatctgaccg taatattgat aaaaatcgcg
   959161 ttgcaatatc tagtctatta gcctcttctg ccctacatag acacttagtt gccagtaccg
   959221 aacgaaccca ggttggtatt attgttgaaa caggtgaggc tcgtgaagtt catcatttct
   959281 gtttaatgat agggtttggc gcagatgcaa ttaatccata ccttgcattt gaggcgttat
   959341 ggcaagcacg ccgtgatgaa ataattgata ttaaaagtga tgatgctatc atatcttcct
   959401 atcgaaaaag cattgctaaa ggcatgttaa aagtcatggc aaaaatgggt atttctacct
   959461 tagaatctta caaaggtgca caaatttttg aagcagtagg cctagcaccg gaaataatgg
   959521 ataaatgttt ttttggcaca gcatctcgta ttaacggtgt taattttgat attttacaaa
   959581 cagaaagtga aaaacgccat caaaatgcct accaaaccaa ttctttagac aattttggcc
   959641 aatactattg gcgtagtggt ggagaaaaac acatgtggga tccacaaaca atttctcact
   959701 tacaaaatgc ggcacgtaat aataacaaat cagcttattg ggcattttct aaacatgcca
   959761 atgaacaagg cacacgaaac tcaacattac gtgggcttat gtctttcaag aaaggcaatc
   959821 caattaacat tgacgacgtt gaaaatatta aaaaaattgt taaaagattc gctacaggtg
   959881 cgatgagctt tggttctatt tcatcagaat cacacgaatc actagcgatt gctatgaacc
   959941 gtttaggtgg aaaatcaaat acaggtgagg gtggcgaaga caaaaaacgc tggacacctg
   960001 atattaatgg tgactcacgc cgtagcgcca ttaaacaagt agcctctggt cgttttggtg
   960061 taaccattga ctatcttaat aatgcggatg agattcaaat taaagtctca caaggtgcaa
   960121 aacctggcga aggaggtgaa ttacctggta caaaagtaga tgaaaatatt gcctcaatac
   960181 gccactccac acctggtgta ggacttattt ctccaccacc tcatcatgat atatattcaa
   960241 ttgaagattt atcacaactt atctttgatc taaagcgctc caatccatca gcacgcatta
   960301 gtgtaaaatt agtcgcagaa gtaggtgtgg gcacgattgc tgcaggtgtt gttaaagcaa
   960361 aatcggacca tattgttatc gctggtcacg acggcggtac aggtgcttct ccactaacct
   960421 caatcaaaca tgcaggcttg ccatgggagt tggggttagc tgaaactcat caaacattag
   960481 taatgaatgg gttgcgttca cgaatagttg ttcaaataga tggacaatta aaaacaggta
   960541 gagatgttgc cattggtatt cttttgggtg ctgaagaatt tggattttca actgcacccc
   960601 taatcacatt aggttgtatt atgatgcgta aatgccatct aaatacttgt ccagttggta
   960661 ttgctacaca agatatagaa ttacgtaaaa aatttacagg caagcctgaa cacgtagtta
   960721 actacttatt tatggtagct caagaattac gtttaataat ggcagaactt ggttttaaaa
   960781 ctgttaatga gatgattggt cgtgttgata tgttacaaat gaatcaaata cttaatcatt
   960841 ggaaacaagg aactattaac ttagatgcat tattaacgcc tgccaaaaaa cctaacaaac
   960901 atacagatac ttatcaaact gttacccaag accatcaatt aaatcaacaa attgacaata
   960961 aactaatcgc aaaatcaaaa ttagctgtta aaaataccga aaaggtttat ataaattcta
   961021 ttatcactaa cgttgatcgt gctgtaggta caatgttatc ctcatatatt gttaaaacaa
   961081 gaggtactaa taacttacaa gacgacacta ttcatattaa ttttaaaggc tcagcaggac
   961141 aatctcttgg tgcattccta gcaaaaggcg ttaccttaga agttgagggc gatgctaatg
   961201 actatgttgg aaaagggatt tcaggaggtt gtattattgt ttatccacct aaaaattcaa
   961261 cctttaacgc tgaaaatgaa attattgctg gcaacgtttg tggttatggt gcaactgctg
   961321 gtgaaatata tttatcgggc tgtgtatctg aacgcttctg tgtacgtaat tcaggagcta
   961381 tcgctgtagc agaaggagtt ggtgaccatg gttgtgaata tatgactggt ggtcgagcta
   961441 ttattctagg tgaagttggt cgtaactttg gcgctggtat gagtgggggt attgcttata
   961501 tttataaccc acatcataca tttgaatcta tggccaatcc aatcatgatt gaccttgacc
   961561 ctatggatag tgaaacgcaa atagaattga aacaatacat aaataatcac gctaaatata
   961621 ctggctcaaa aatagctaca cgtattcttg acaactggca cagtgaaatc aaacacttta
   961681 ttaaaatcat gccaaaagat ttcaaacgtg ttttagccaa aaaaattaca tcaaaccaat
   961741 tccaacaaaa ataaaacaat aactaaaata tattataaac cataatgaca gcttactttg
   961801 taagcattag tatgtattcc tttgtaaaac aataaaatta taggtataaa aatttttctc
   961861 atcaggttta tgagattcac gactaagttc gataaattta gtacggtcaa attctggaaa
   961921 gtacgcatcg ccatcaaaca tacctttaac ttcagtgata tacaatctat caactttatc
   961981 tattatttga tcgtaaaaag atgaaccgcc cacaatcatc agttcattgt cattattagc
   962041 caaacttaat gctacgtcaa tactactaac aacctcacag ttatcggctt taaatttagt
   962101 gtttttactc acaataatat tacgacgatt aggtaatgac ctaccaatag agtcatgagt
   962161 cttacgcccc attaaaattg tttttcctat tgttatcttc ttaaaataag ccaaatcagc
   962221 tggtaaatac caaggcaaag aattatcttt accaatcaaa tagttgtcat ccatcgcgac
   962281 aataatagat aatttcatag aaaaggtttc gaataaagta aaatacagcc tattttacaa
   962341 actattaatc atcatgatct cattaattct agcctcaaat tcacctttta gaaaaacatt
   962401 acttgccaaa ctaggtttag ccttcgatac acatccgcca aaaattgatg aatcaagaaa
   962461 aaagggtgaa acacctgaga aattagttta ccgtctagct caggaaaaag ccagagaaat
   962521 aggaaaaaca cacagtggtt taatcattgc ttctgaccaa gtagcaacca ttaataatgg
   962581 ctttaataat gatgataaca tactaaccaa accaaaaaac cataaggaag ccattaaaca
   962641 actacagcaa aattcttgta atacagtaaa ttttcttaca agtttgtcac ttttaaatac
   962701 aaacacaggt aatatgcaaa ctaaagttga aatatttaag gtaattttta aaaaattgaa
   962761 tattgatcaa attaaccatt atcttaaaaa agaaactcct tataactgcg caggtagttt
   962821 taaatctgaa agcctaggta ttggcttatt taaatgcatg attggtaatg atccaaatag
   962881 tttaattggt ttaccgctta ttcaactcat tacaatgcta gaaaatgaag gtattgacat
   962941 tctaactgac aatatttaga tatgatgcca tatctctatt ccaacaaagt taaatgcttt
   963001 gaattaggtc gaaaaatgta ttggggttca ctatatggta gtgcagatgc attggcatta
   963061 attgaattcg ccaaccaaca acatatcatt ttagtaattg ctaatgatat tgtacatttt
   963121 gataattttt ataaatcttt aaagttttat aacactgacc tagaaatttt aaaatttgat
   963181 aattgggaag ttcttgccta tgattacttc tcacctcatc ctgatattac ctccagtaga
   963241 ttaaaaacct tatcaaaact taaaagtctt aaacgaggta ttgttatcac cacgttagag
   963301 tcgttatttt cacacttatg tccactagag tttagcaaaa aatatagctt aaatattcgt
   963361 attaatgaca aaattaatcc tgatactttt agtgaaaaat tactaaaaat tggatacaag
   963421 catgtaatca cagtaatgga gcatggtgag tttaatatgc gtaattcatt gattgatcta
   963481 tacccgatgg gtacaaaaac agcttatcga attaatttat ttaaccaaaa agtggaatcc
   963541 attcgcgcct ttaacacttc aactcaacgt tctaaaacta aaatacctga aattacacta
   963601 ttgcctgcta gagagtttgc aacagataat actagtattg aatactttaa aactaattat
   963661 aaaaaaatat ttaatgataa tggttttatt tataccgaag ttagtgaagg aagattacca
   963721 ggtggtattg agttctattt accattgttt tttcacacaa caaatacctt atttgactat
   963781 ctagcagata atactattat tgccacgtca aaagaatttt cgaacttagt ggataaaact
   963841 tataacgaaa tacgtgaacg atttgaaaat gctaaaaaat cattagacag agcaccactt
   963901 gacattcaac gagttttcct atccaaagag ttgctcttta gtgaagtcaa gaaaaaatca
   963961 cagattataa ttagtacatc taaactagaa aataaaaagc aacattttaa ttttaactca
   964021 agtctaccac cgccagtacg cattgaacta caaacgaaca atccgttaag caaattttca
   964081 acatttgtta aaagatttac taacaaacaa aacaaaaaaa tattaattgt ttgtgaatca
   964141 ctcgatagac aaaatgtact aagtgattta ctcatcaatc ataatcttaa tacttatagc
   964201 gttaagagct ggcatgaatt tactactagt agtaaatcac ttaacattat ccatgaagat
   964261 cttatccatg gtttgcttat ccataatatt gctattatta ctgaagaaga tttatttggg
   964321 caagaagtag ttcaacaaca acgtcgtcat accaaacata aatattttga cgtagctatt
   964381 aagagcttag tagagattaa aataggcgat gctattgtgc atgaaaatta tggcgtgggt
   964441 agatatttag ggctcaaaac caaaattttt gataaacaat cacaagattt tcttgtccta
   964501 aaatatgcca ataacgcaaa attaatggtg ccaatcatct catttaatct aatctctaga
   964561 tatgctggaa tttcgctaaa aagtacgcca ttacacaaac taggaaccaa ccaatgggcc
   964621 aaggctaaga aaaaagcagg tgaagcttta tttgatatag cagttgaatt attaaaaatt
   964681 tctgccaagc gatcctctca aacaggcttt tctttcccta agcctaatga tgattactct
   964741 tcatttgttg ccaattttcc ctttgaggaa actccagatc agataaaaac catgaatgaa
   964801 gtactagcag atatgcaatc acaacaacca atggacagat tggtatgtgg agacgttggt
   964861 tttggaaaaa ctgagattgc catgcgtgca gcttttttag cagttaaagc aggtaaacaa
   964921 gttgcaattt tagtaccaac cacactatta tccaaccaac actatcgatc ttttatcgat
   964981 cgtttcacta atgatcctac aaaaattgca acattatcaa gattccaaac cccaaaagag
   965041 caaaaaataa ttattgaaca actaaagcaa ggaaccattg atatcattat cggtacacac
   965101 aaaattattc aaaataatat taaatataaa aaccttagct tgattattat tgatgaagaa
   965161 catcgctttg gagttaaaca aaaagaagct ttaaaaaaac tacgaggaca aagtgatatt
   965221 ctaaccatga ctgccacccc tattccacgt acattaaata tggcactagg ttcattaaga
   965281 gaattatcta ttattgcaac gccaccagct aagcgcagta ctatccaaac ttttgtacaa
   965341 gaatggcata acgataatat caaagaggca attacacgag aaatacaccg tggtgggcag
   965401 gtttttatac tgcataatga tattaattca attgacaata tggcagaaaa tctaaaacaa
   965461 attataccaa aattacagat tcgtatcgcc catggaaaaa ttccaacacg tgagttagaa
   965521 caaatcatga gtgattttta ccacgcacgt ttccacattc tagtttgcac cacgattatt
   965581 gaaacaggga ttgatattcc taacgccaat actatcatta tcaataatgc acaaaatttt
   965641 ggtctagcac aattacatca acttagaggt cgtgttggtc gttctcacca cagggcttat
   965701 gcttatttaa ttgttaagtc tcatctatct ttatctaaaa cagctaaaga tagacttgat
   965761 gtaattaagt ctttaacaga acttggttct gggtttatgt tggctaatca cgatcttgaa
   965821 attcgtggtg caggtgatct actcggtgat aatcaatctg gacaaatcag cgaaattggt
   965881 tttaaccttt accatgattt attgaaacgc accattgatg ccgtgtactc tggtaaaaaa
   965941 attaacctta atgatccaat taaccatgaa gtacaaattg attctggctt accatcaatt
   966001 attccagaaa cctatatttt tgatgttcat gaacggcttg tgctttataa acgcattgcc
   966061 aattgtcaaa acaacaatga acttaaagcc ttgcaaattg aaatgattga tcgttttggt
   966121 ctgttgccag attcaactaa aaacttactt tacaatacca aactaaaact cttttcccaa
   966181 ataattgggg tgaacaaaat aatcctttat gaagacaagg ccatcattac ctttaacaaa
   966241 aaaaacacca ttgatcctat aaaaatcacc aaccttatcc aaaaacaagc aaaaaaatat
   966301 cagctaaaag atcaaaatca attaattatc aaagaacaaa tgcctaaaaa tattagacga
   966361 atcaaattaa tagaatacct attaaaaatg ttaaattaat tcaattataa taattaaaat
   966421 aataactctc catagttatc ttgataatat ttttcaatat aacccatatc aaattggtgg
   966481 ttttgcgcgc ctaaatgtgt aactttaata gcaccaagta accctgccag ttgtcctata
   966541 gttttccaat ccatcccatt cattaaacca tataaaagtc ctgcacgata agcatctcca
   966601 caacctgttg gatcttgaaa aacatctact ttaacagggg taatattgat tactttttct
   966661 tcagtatgaa tttctgaacc ttgtatacct ttggtgataa atagcgcctt tacttttata
   966721 gcaatggttg ctaaatttag tccagttcta tcttgtaaca tttgtgattc ataactattc
   966781 actaccacat aactagcttg ttcaataaaa ttgattaact cttcacctga aaacattggc
   966841 ataccctgac ctggatcaaa aataaatggg atatttaact gcttaaattg tgctgcatgt
   966901 tcaatcattc cagtacgtcc atcaggggat acaataccaa tatcaaccat actaacatca
   966961 aataccttat tttggtgcga ctgatccatc gcaccaggat gaaaaacagt aatttgatta
   967021 ccgctcatat cagtggtaat aaacgcctga cctgtatatt gacctggaat aattttaata
   967081 tatgcggtat tcatatgaca ccttgtcatc cattctaaat aaggtgtgaa atcactacca
   967141 actgttgcca tcggcactga attaactccc aataaatgta agttataagc aatattacca
   967201 gcacaaccac caaactcttt acgcatagtt ggtactaaaa atgatacatt tagcatatgc
   967261 actctatctg gtaaaatatg gttattaaaa taatcgtgaa acaccataat actatcaaaa
   967321 gcataagagc cacaaattaa tgctgttttt gtcatattat tttttctttc ttttttttaa
   967381 agtatcctat taaacttgat atacctatga taaataaaaa ttcctatctt aattcttttg
   967441 gtactggaaa atgaatattt tcctttacgc cccccacttc aataacttta gttgcgccct
   967501 tatctcgtaa ataatgaaca acttcttgaa ctagaacttc tggcgctgaa gcacctgcag
   967561 ttacacctat tgtatcaaca cctttaaacc ataattcatc aatattatca ataccatcaa
   967621 ttagatatgc aggaatacct attttttcag caatttctct aagacgattt gaattagatg
   967681 aattactaga acctaatatc aacaatacac tagaaaattg catcaaaatt ttaactgcat
   967741 cttggcgatt ttgcgtagca taacaaatat catctttctt aggcatatca atagttggga
   967801 ttcttaattt taaataatct ataatagatt gagtatcgtc aattgaaagt gtagtttgtg
   967861 ttgtataaga aaatgacatg ttttttgata aatttaaacg ctcaacatct tcaattgttt
   967921 ccactaattg aacacaatta ctttcactag attgacctaa cgtaccctca acctctggat
   967981 gacccttatg cccaattaaa attacctgat aattttgttt ttgttttcta gcaacttctt
   968041 tatgcacttt agtaaccaaa ggacaggtag catcataaat aattgcgcct atattgtgtg
   968101 tttgcctacg cactgcaatt gatacaccat gcgcactaaa aataaccact tggttgttgg
   968161 gcacatcagc aatatcctca acaaaaacag cacctttatt cttcagtcca tcaactacaa
   968221 atttattatg cacaacctca tgacgaacat ataccggcgc accatgtaac tttaacgcac
   968281 actccacaat ttcaattgca cgatcaacac cagcacagaa tccacgtgga tttgccaata
   968341 aaactttcat tgtttttgaa gtattttcac ctgaaaagag acatcattac cagcaagtgg
   968401 atgattaaaa ttaacggtaa tatcatcatt cttaatttta tcaatacaac ctacataaga
   968461 atctcctata ggagttttaa attcaacaac agaatctaac tcaatcatca tagtttgtgg
   968521 gaaatctaaa cgtttcataa tttgaaaagc ttcttctagt tcattaccaa acgcttctga
   968581 tgcacttaaa agaaaagttt gcagttttcc aacttgagcg tcaataacac atgactctaa
   968641 gcaaaaatcc aattgaccat cacccaattc aaactcaagc ggatcatccc aagactcatc
   968701 aatcaaagta ccatttgcat gactaaattt ataaaaaatt ttgtatttag tcattattaa
   968761 atgtcatagc acttaatatt ctatgtactt gagtacgtaa ctcagaacga tgcacaatca
   968821 tatcaatcgc acctttgtct aacaaaaatt cactacgctg aaaaccttct ggcaatgctt
   968881 cacgtactgt ttgtttaacc actctaggac cagcaaatcc aattaatgcg cttggttcag
   968941 caatatgaat atctcccaac atagcaaaac tagcagaaac accacccata gttggatctg
   969001 tcaaaatcga aataaaaggt acttttttat cacttagtaa cttaattatt aaagctgttt
   969061 tactcatctg catcaacgaa aaaagacctt cctgcatacg cgcaccacct gaggctgaaa
   969121 aacaaatcag cggtgtatta gttttaatac ttatttttgc agcacgaaca aacttttcac
   969181 caacaacaga acccatagaa ccacccataa acttaaattc aaaagctaca accacaacct
   969241 ttataccatt gagtgtccct attttaacta caagcgcatc tttttcatgg gtgatccttt
   969301 gcgcttgtaa ataacggtct ttatattttt tttgatcttt aaactttaga gggtcaaccg
   969361 cgcttaaatc agcagcaact tcttcctgtc ctttcttgtc taaaaatcca tcaatacgag
   969421 ccctagcagt aagacgaata tgataatcac acttaggaca aacataattc aatgtcttca
   969481 actcttctga ataaagcgta gtttcacact tagggcactt actccataaa ccttttggaa
   969541 tatctttttt cactacacta gtaatagaag gtaaaatttt ttctagccaa ctcatactat
   969601 tttccttatt ttaactattt aattatggta gaaatctcat ttgccaaata cccaaccttt
   969661 gctaacattt tagttctatc attcgcatat cgctcaacca atccaaccaa tgatgaacct
   969721 acaataactg catcagcata ttcagacact atctttgcac ttattgcatc tttaatacca
   969781 aatcccactc caataggcaa atcaattact tgacgaattc ttaaaatatg tgtttttacc
   969841 aaattaatat ccaaatattc tgcacccgtt acacccttaa gggaaacaaa ataaataaag
   969901 cctgaggcaa tagtagctaa aaataccaaa cgctcatcca ttgttgttgg cgcaaccaaa
   969961 aagataaaat tgattccgac accatccaaa atttgcttta aaccataggc ttcttctggt
   970021 ggcatatcca ccactaacac accatcaaca ccactttcac tagcggcatt ggcaaaaggt
   970081 tgataaccaa aaacttcaat cggatttaaa taacccatta acacaatggc tgttgtatta
   970141 ttagtttgtc taaatttctt aaccacagta aatacatcag ataaactaac tccatccttt
   970201 accgtacgct catatgatct agaaataaca ggtccatcag ccatcgggtc tgaaaacggt
   970261 acaccaagtt caatcacatc tgcaccattt ttaactaata cctgcatcaa ctcaaaggta
   970321 ttatcaagtc cactatcacc tgcagtaatg aatgggataa aaaccttatg atttttaggt
   970381 gaatcaaaaa atactctact aagacgcgac atattatcta cactccttac taaatgtatg
   970441 cacacaatca accaatatct ttacattttc aggatcaaca tcaggagtaa taccatgacc
   970501 aagattaaaa atataacctg tatctccttt aaattgtgac aatacttttt taacttcacg
   970561 ctcaattact tcaggtgtag catacaaaac agctggatca aggttaccct gaatagcaac
   970621 tttattaccc acttcttgtt gcacttgata aagttctact gtccagtcta tacctacacc
   970681 atcacatcct gtattagcaa tatgcgttaa atacttacca ccattcttac taaataacgt
   970741 aatgggaata tttggatgtt gagctttaac acctttaact atttttgcca tataatataa
   970801 tgaaaaatct aaataatttt gttcagataa tacaccaccc caagtgtcaa aaaccatcac
   970861 actatctgcg cctgatacaa tttgttgatt gagataggca atcacacttt ttgtcaactt
   970921 cattaacaat aagtgcaatg cttctggatc attaaatagc atttttttag tactagcaaa
   970981 gattctacca ccaccttcaa tcatataagt cgccaaagtc catggactgc cactaaatcc
   971041 aatcaaaggt acacgattat tcaatgattt tttaatggtt gaaaccccgt caaaaacata
   971101 acttaaatca ttattaaggt cggtagatat ttttttaata tcttttaggt ttttaattgg
   971161 atttctaaat tttggtcctt caccttccat aaagtacaaa cctaaaccca ttgcatcagg
   971221 aatcgttaaa atatctgaga ataaaatagc tgcatctaag tcaaatcgat caataggctg
   971281 catggtaact tcacaagcca attctggcga tttacataac gttagaaaat ctccagcttt
   971341 tgcacgtgtt gcacgatact ctggcaaata acgacctgct tgacgcatta tccaaatggg
   971401 cgtgcgtgag gtgggttttt ttagtaaggc attaatataa tcaaatgaca taagctttaa
   971461 acataaaaaa agtaaacact atagtcagac ataaaaaagg ccactttcgt ggcttttttt
   971521 attgaatttt gtcttcttat cttttaaaac tagcatagcg tgatttaaat ttctcaacac
   971581 gtcctgcact atccataatt ttttgcttac ccgtataaaa aggatgacaa ctagagcaca
   971641 catccaaatg caactccttc ttatcaatag ttgaacgagt cttaaaggta ttgccacatg
   971701 aacaaataat ctgaacgtca ttataattag gatgaatact tgttttcata ttaatattaa
   971761 ctatttttta aaatcgtaaa attaatgaag ataaattata tactatttga aactcataac
   971821 aatgctattt ttatttgttt cttaaacgtg cagcattacc aatcacaatt aacgaactaa
   971881 taggcataac aatagctgca aataatggtg taacctttga catcatagcc aatggtatca
   971941 taaaagtatt gtacagtaat gcaaaaataa tattttgtct aataatacta ttagtatgct
   972001 ttgccaagtt aataagatca ataattgggc taattgtaga ttctaagata accaaatctg
   972061 cactattaac cgatacatca ctacctgaac caatagcaat actaacatca gcctgtacta
   972121 gagcaggagc atcattcact ccatcaccta ccataagtac tatatgtctt tgttgtaatt
   972181 gttttatata attggcttta tcttttggta aagcttgcga aatcatatgt tcaataccca
   972241 actctaaggc aatagcttga gtcactattt tactatcacc acttaatatg ctaacttgct
   972301 tacctataga tgtaagctga ttaacaacct tagcagcatc taatttaatc ttatcctgta
   972361 aaataacaaa ccccaacact tcagattcag tagcacacca aatgcaacta gctccttgtt
   972421 cctctaatat gatagattta tttaataaat cagtatttac cttatgatga acatccacat
   972481 aagataaatt accaatttta taccgttgtt gatcaacaat accactaacg ccttgaccat
   972541 agtcagcgta aaatccacta actgctaaat atttactagc aaaatcaata tcaacaattg
   972601 ctttagctaa tggatgttca gaataccttt caatacttct catgatattg ataaaaattg
   972661 ttttatcaat cacagtttca atgtggctaa tactaaattt acctctagtc agagttccag
   972721 tcttatcaaa aactacccaa tccactttat ctaatacttc cagtgcatcg ctatttttaa
   972781 taagtatttt tttcttaatc gctacaccac ttgcaactgc aacactcatt ggtgtagcca
   972841 aaccaaatgc acaaggacaa gtgataatta gtacactagt agcacttaac aatgctaaat
   972901 caaaatcata tggataccaa taaatgaagg tcactattgc caataaaatt gtcataccaa
   972961 caaaataagg aataatttta tcaagcatac aaataattga acttttatta tatttagtag
   973021 tttcaactaa gcttacaatt tgtcccaaag ctgagtttct taaggttttc gttactttga
   973081 ttatcaaact cccactagca ttaattgaac cagcaaacac ctcatcacta gattgttttc
   973141 taatcaataa agattcacct gtcaataatg actcatctac ttcactatta cctgacaaaa
   973201 caatcccatc tacagctata cgctctgcag gcttaatcaa aacagtatca cctattttaa
   973261 ttatacctac tggagtaatt tgttcctcac ctttattaat aacataagca accttaggtt
   973321 gcaactgctg caatgcacta gaggctgata aggtagattt tttagccgaa ctttcaagat
   973381 aacgtccaat taaaatcaca aatataaaat taactactgt gtcaaaatat acttcattct
   973441 tagcggacaa tccaaataac acatatacag aataaaaata cgtacttaaa gcaccaatac
   973501 taattggaac gtccatattc ataaaacaat ttttaagtcc aaaataagca tttttaagaa
   973561 atggcatacc cgcataaaat agagtaggag tcgctaatac aaaactcaac cattgaaaat
   973621 aatgatgata tttcccatct gttgcccctg tgtacaaagc aattgaaatc cataataaat
   973681 tcatcatcgt aaatgcacta aaaccaatac gataaagtat caatcgattg attttattag
   973741 caacagattc agctatatct tgttcgtatg gcattgctga atatccaagg tctgctaatt
   973801 tttgcataat tacagacaac tgaatatcag tatcaaccca actaagacga atacgcttat
   973861 cagttaaatt aacccgtacc caaagtacgc cattaagagc attaatcgct ctctcaatta
   973921 accacacaca agcagcacaa tgaatggtat tgctaattaa agtgatagtt ttagtaccac
   973981 tttcataaga agactctaaa aaaggctgct gaaaagcctg tgcatcataa aactctattg
   974041 gatattccaa atcaattgca ggtaataatg aattagtttg ctgatgataa aaagagctta
   974101 gtccgcttag atagatagtt tgacatacgc ttgcacaacc agaacaacaa aaatcttgct
   974161 gtttgccttc aattggcact ctaacttgat tacggataat gacttctaat ccacaatgat
   974221 aacagctatt actcatagtg gttgatttta ttgtatttat accgttaaac gtttacaata
   974281 tcaacccaaa cctctcatta acttgataca attgatgaaa cccataaaac aacaactctt
   974341 tcatataaaa actcagcaaa tgataactaa ctacacctat tatttcttaa acaataatat
   974401 acgctctata tttttatacg tgtaaatcac actttgtgct taagctatga ataaattatc
   974461 catacaactt atcgtactac ttagtttgtt attctttagc aataaaagta tctctgagtc
   974521 tccaattcat ctttataaac aatacttaat tggtacgcca agagcttatt tacaaaaatc
   974581 acatccatta gaagattgtt ctgctaaata cgaaaaaggc acactgtgta tgaaaaatca
   974641 tttattagca ggtgagaaag ctgaaattgc tttccggttt ttaaatgaca aacttgtttc
   974701 tattgtgctg ataatgacac taactgacgt gagtaaaatt aagaaaatat tttatgtatt
   974761 aaaaacacaa tttgatttag tattaattga agatggctac aataaattag atattattca
   974821 aattaatgcc agcactttta ataaacatga atttactaaa ataatcgcta attttgagaa
   974881 tgaagcctac caaaagcaca atattaaata cacttttatc agcaagtatg aatttattac
   974941 ccaatcacgt aaatcacgta atttttctga tatttttaaa aatgcaccaa tgcgaatgcg
   975001 cgctgcaatt tatagtatag gtcgaaaaga tgaacaagtg attggtacta ttagttttat
   975061 tgtgcctgga gttacccaat cttatcttga tcaaaatcca attgtagagg atttttaagt
   975121 tgtcattatg aataatattc acgctattat tctagcagca ggcaaaggta cacgcatgaa
   975181 ttctactaaa ccaaaagttt tacaaatctt atcaaataac actttattgg aacatgtact
   975241 atctcaagtt aaaaccttgt gtaataaaat tcatatagct tacggctttg aaggcaagca
   975301 agtacaacaa aaaattaata accctagtat taactgggtt aaacaagtta aacaattagg
   975361 cactggacac gccgtagcac aagtaatgcc gtacattgaa ggtaattcaa tttcactcat
   975421 actatatggt gatgttccac taattaaaag atccacattg tacgatttaa tcaacaagac
   975481 acaacaaagc ggtattgcct tattatctgt tattttaaat aacccaactg gctatggacg
   975541 cattattcgt aataataaac agatacaagc cattgttgaa caaaaagatg caagtaatat
   975601 gcaactgaat attaacgaag tgaatacagg aatcatggct attaattcac aattattaaa
   975661 acaatatttg aacgaaattg actcaagaaa cacccaaggt gagctgtatc taactgatat
   975721 tattgcttgt gcggctgctg ataaaaaaac tatttcatcc attattagca aaaataaatt
   975781 tgaggtatta ggtgtaaatg ataaagtaca attagcagaa ttagaacgtc ttttccagaa
   975841 agatcaagca atacaattta tgaaacaagg acttggatta aaagatccta ctagatttga
   975901 ttgccgaggc acattaacct ttggacagaa ttgcgaaatt gacgttaaca cactcattaa
   975961 aggtaaagta gcacttggaa atagcactac aattgaaccg aattgtatta taaaaaacac
   976021 tataattggt aatcatgtat caatttttcc aaactgcgtt attgaagatg ccgttattgg
   976081 agaaggtgtt actatcggac catttgtaca tattcgccca caaacccata tccaaaccca
   976141 tgctaaaatt ggtaattttg ttgaaattaa aaaatcaacc attggtaaaa ataccaagat
   976201 ttcccatctt agctatgtgg gtgattctac tattggaaaa aatgttaata ttggtgcagg
   976261 tgttattact tgtaattatg atggtgtcaa caaacatcaa actataattg ctgatggtgc
   976321 attcattggt tctgactctc agctaattgc acccatcaaa attggtaaaa atgctaaaat
   976381 tggtgcaggc tctaccatca caaaatcagt atctgaaaat cagttaagtg taagccgtac
   976441 taaacaaaaa aacctaaaat accgttctaa aaaataaatt cacttccttg taatgtttga
   976501 tgattaacag tttctattat tttactggac actaattacc atcataatat ccatttgtca
   976561 agtccaccaa taatttgtat ctacacaatt ggtattattt tacctgctat ttacagcatt
   976621 acaaataaaa ttcactttat ttattctact tatccacctt tttgtttagt attactacaa
   976681 tactataaat cagtttaaat tcacatcaaa tcaaaagtta ttgttatgtt atacgtatta
   976741 aaaacacctt atttatggaa aacatagcga tataccttaa aaattaaaca ctcaccaaaa
   976801 aaataaaaac gctttccaac tataaagtta accataaaag actcataaaa gataattata
   976861 atgataagaa atgcttagat tggtctttat actacaataa tttctctgaa agaaatcttc
   976921 aggaaaataa tctaatactt gtaaagtaaa ttttttaaaa tttaatatag tatttacaaa
   976981 aaaaaagata taaattaatc ttattcaaaa gaatttttta taaatctttt aactcatatt
   977041 tattaacatt caataccttc aatttgtgca atagtgtgga tatccttatc accacgacca
   977101 gaaaggttaa taataatact tttattttta cctaattttt ttgcaagctt gataccataa
   977161 gccacagcgt gggaagattc taatgctggt aaaataccct caattttagt aagtatatga
   977221 aatgcttcta atgcttcttt atcagtaatc gccatatatt gtgcacggcc actatctttt
   977281 aaatacgcat gttcaggccc aacccctgga tagtcaagac ctgctgcaat tgaatgcccc
   977341 tcaataattt gcccattctc atctcccatt aaataagttc gattaccatg taacacaccc
   977401 acattacctg cacaaagtgg ggcagcatgt gcacttggac ctttttccaa gccatgtcct
   977461 gctgcttcaa caccataaat ctcaactgaa acgttatcaa taaatgcata gaataaacca
   977521 atcgcatttg aaccaccacc cacacaagcc accaaagcat ctggtaaacc acctacctga
   977581 tcatgaaatt gtgcttttgc ttctttacca ataatacttt gaaaatctcg caccatcatt
   977641 ggataaggat gtggacccgc tattgtgcca ataatataaa acgtatcatc aatattcttc
   977701 acccagtcac gcattgcttc attaagagag tctttaagtg tttttgaacc tgaagtaact
   977761 ggaataacct tagcgcctaa taacttcatt cgaaatacat tcagagattg tcgagctaca
   977821 tctacctcac ccatataaac cacacactcc aagcctaaac gcgctgcaac cgttgccgtt
   977881 gctaccccgt gctgaccagc acctgtttca gcaataatac gtgttttccc catacgctta
   977941 gcaagtaatg cttgaccaat agtattatta attttatgcg aacctgtatg atttaaatct
   978001 tcacgtttaa gatagatttg agctcctctc aactttttgc ttaaattttt cgcataataa
   978061 agtggcgttt cacgaccagc ataatgcttt aaatcctgct caaattcaca aataaattta
   978121 gaatcatttt taaatctagc ataagcatct ttgagttcaa aaacagctgt cataagcgtt
   978181 tccgcaataa aaataccacc atacttatca aaatgaccat tatcatctgg taaattataa
   978241 ttactcataa gtttgccttc tgaataaatt gtttaatctt attaatatct ttaattcctt
   978301 tttcactttc aacgccgctt gacacatcaa ccgcataagg atgtacttga ttaatagcat
   978361 tatctaccgt attagaattg agaccgcctg ctaagataat aggtagatta atatcaaccc
   978421 tggccaagcg ccaatcaaaa ttctcacctg tacccccata aatatctttg ttgaatacat
   978481 ctaacaataa accactagcc tggtgatact catctgccat ttttttgata ttagtctgca
   978541 cattcatatg aagcgcctta ataaatggca tagtatattg agcacattca tgtgctggtt
   978601 catctccatg aaattgtaac gtatctaatg gtactttaca taacacctta tcaataaaat
   978661 tagaatcaga attcacgaac aatcccacac gattcacaaa tggtggcaac acattcacaa
   978721 tatcaatcgc agttccaaca ttcacataac gtggggattt gtcataaaat accaaaccaa
   978781 tcgcatcaat atcaagcatg gcagcttgat tagcattatc tacactagta aatccacaaa
   978841 tcttaatcct catctactta ccatcaatat ctaattttgt cttgatctta tctctatcaa
   978901 tccaccaatc atcaactact agttgatcaa tagcgcctga aagttttctc aaaaacacct
   978961 ctggctggtc tagctgtaaa gttttacacc ataaatcaaa agttgactga tcagttacat
   979021 gagaatgctt atctgcaaca gatgccatca tttgtgatga gaaaaaagtt aaatcgtcat
   979081 ccaaaccaca acgcatagaa gtaatataat gcgctgttgt agcagcaata gcacaaatat
   979141 ctgcctcttt tggtgactca tcaaccaaat gttgtaacat cgcaacactt aattctgggt
   979201 taattggaaa agtaacgcct aaccacaaag catgacctaa tgcctttaaa gcttttggtt
   979261 cttcagataa aaacataaca tcacaagcct caactgctag ctcccaaagc tcattatccc
   979321 ttgcaatatc aaaggcaata aatgcttttt cccaagcatc taaaccctta taaagctcaa
   979381 cttgaattct accgatttct aataaattat taattttctc ttcaacagga gtatcatcag
   979441 tttgcacctg aattttcttc tcaaaaaact taagtctaga tttaagttgt tcctcattga
   979501 cgtataaatc ttcaccatct tcagcatcaa agatttgttg tttatttaaa tactttccca
   979561 tccagatgct tcttaataaa aagaagcttc taagcgatct tcccaattat taggaacatc
   979621 aatataatca ggtttcacgt ccatcctaaa aaacaattca tcagaccctt tagacacttc
   979681 tcctaaaaca acaaccaatt cctcaaaatt atccacctct ggattagaaa taataacttc
   979741 acttaataat aacataatct ttcagagaga aaaaatttaa tattttacac ttgtatgact
   979801 tgatatatat taacctaatt tgcaactttt ttaatatcaa ataaagttgt tcatcttact
   979861 cataccactc cgtatactat atttttttca tccttcatca attaagatat tctttatacc
   979921 actaaaacct atttttctcc ataattaaat cttaatcaaa aaataagttt atttaatact
   979981 attttttttg ttgacaatta ctaatttcaa aacccttatt aaaacttcta acactcttat
   980041 atcaataatc atatcattgg ctcccataat ttcttataaa cactttttca ataaattcta
   980101 ataacctaat atctattaat tttaatgttc ttgaatattt tactaatttt aaaaaagttt
   980161 tagtaaattt tttaattgat ttaaaatttt taagaaaacc ctaaattatt ttatctatat
   980221 agctatttac aaataggatt catattaatt tccttttata agacccgcta aaactaaaaa
   980281 atagatcaac ctcagtaatt aaattgataa atttttcatt acactagcta tttttagtaa
   980341 cttctttctt aactatcttc ttttttagtt tcagtttgcc agaaatagct tttttacatt
   980401 cttcaagggt taaatttgct ataggtttat cgccaaaaac tttcttgata gtaatatttt
   980461 tttggccctt gcctttcttt tttccattcc aaatataagg accaaaacga ccattaagga
   980521 gttgtatatc agaaccatca aatattttta taatacgttc agagtcgaat ttttctttga
   980581 ttttaataag ttctaatgct ttttctaggc tgacttcttc tggaatatct tctttaagcg
   980641 aaacgtattt tttaccatat tgaatgtagg gaccgaaacg accgtaatta gctttaatag
   980701 tgccaaaatt atcagtttca ccaaggtgac gaggcatatt aaacaattct aaagcttcat
   980761 caagagtgat gctttcaata tctaataaac ctctaaacga ggcaaaggtt ggtttatctt
   980821 tatcgtctgt atgtccaatc tggacaaaag caccatatct accaacacgc acgctaacgg
   980881 gtttgtcact ttttggatcc actccaagat tacgcatgct gtggatttct tctctagaaa
   980941 tattaacagc atcttctatt ttttgatgaa aagggatata aaaattctta accacgcctt
   981001 gccacgaaat attttgtgta gctatagtat caaaatcact ttcaagttta gcagtaaatt
   981061 tataatcaat aatattatta aaatatttaa ctaaaaaatc agtaagtaaa taagcaatat
   981121 tagttggaaa taatttattc ttttcaccgc ttattacttc gcttggttgt gactgaatga
   981181 cttgattgtc tttaatttca atcagttgat actcacgttc cacacctctt ccattttttt
   981241 ttgtaacata atttctatct tgcactgtag ataccatagt agaatatgtt gagggtctgc
   981301 caatacccat ttcttcaatt tttttcacca atgaagcttc ggtataacgt ggtttagcac
   981361 gagagaagct ctctctagct ttaaaattaa ctaaatttaa tgcattacct ttgtttaacc
   981421 ttggtaataa tttatcttct gacaagagat aatcataaat ccttaaaaac cctggaaata
   981481 ccaatacttc tccattcgct ataaatattt catcaagccc ttcaatatta atttttattt
   981541 tagttttttg taactgagca tcgctcattt gacaagacaa agtacgtttg taaataagga
   981601 tatataattt agcagcttgc tcttcaatat caaaaatatt agacctggtt aaatcagttg
   981661 gacgaatcgc ctcatgtgct tcctgtgccc tggattcttt agacttatat cgtcttgtgt
   981721 tatgatattc actaccaaat tctcttacaa taattttgtg aactgcctca attgcagttt
   981781 ctgatagaat aaatgagtca gttcgcatat aagtaataaa acccttacga tataaatttt
   981841 gtgccaagat catggtttgt ttaactgaga agcctaattt ttgaaaggct tcttgttgta
   981901 aggttgaagt aataaaaggg ggtttaggag aacgtttaaa gggttttttt tcaattgatg
   981961 taatagttaa gttagccaat aaaagtatat tagcaaaggc taatacttgc tttttagatt
   982021 taaactcttt gctcaattta accttaaata tctcaccgct ttcactcgat aactctgctt
   982081 tgactttgta agtagaatta tcaatatgtt tgctaatttc tcgttctctt tctaccacaa
   982141 gacgtaccac tggagattgc accctaccag cagaacgtgc accagaaatc tttcgccata
   982201 aaatagggga tatttcaaaa cctactaatc tatcaataat acgacgtgct tgttgagcat
   982261 ctacaagtcg atagttaact attctaggct ctgaaatagc atgagtaatt gcatttttgg
   982321 taatttcatg gaaaacaatt cttggagtgt ctttaggcaa attaagtgct tctaataaat
   982381 gccaagcaat agcttcaccc tcacgatctt catctgttgc aagatagact ttttctgcta
   982441 cctttacagc cttacgtaaa tcggtaacta cctttttctt gtctgcggtg atttcataag
   982501 taggggtaaa gttattatca atatctatac ccatattttt cttaggcata tcacgaatat
   982561 gaccaatact agatttaacg ctaaagtctt tacctaaaaa tttttcaata gttttggctt
   982621 tggtaggaga ctcaacaata acaagatttt ttgccattat tgaatggtac gattttcatc
   982681 aagaaacacg attgattcta gccattgtgt tgatgtttca ccatcgacac tattacctaa
   982741 taccatcata actacccact taaggtcttc taaagagata ctagtatcac ccaataacat
   982801 aatctgatca ataatcattt cacgctgatt accatttagc tgaccaatat tttccataaa
   982861 caacaaaaat cctctagatt tagcattgag ttttattttt tcagtcttag tataaatacg
   982921 tatactacct tgataagtcg tcttaaatgg cttaatcttg ccatcttgaa tggtggctat
   982981 cttttctagc caactaagtg ctttatcaat acgcattgtg tcaaatccga tgtctgaaag
   983041 atgtgctttt aactcagtat tatcaatttc atgagtagca tcttgctctg cctcttcaaa
   983101 aagataatca aacatgtaag ttagaacatc aagaatatta tttgtcataa aaatctcact
   983161 tagttagtta cataacctaa attagttaat ttaaactacc ttatttttag gcttaaggta
   983221 atctacgagc taaggttctt atttatcaac cctcactaca tcataactca gacattttaa
   983281 tagaatagag tctattttgt ctacaatttt tacataagca agctcacgcc tttaatagga
   983341 ttagatagtt tatcaccttt cttaataaat tgatgatagg ttattgatct ggatattgaa
   983401 aatacctctt tatcttatat taataaataa ttttttagta attatagtac tacttttaat
   983461 acttaccact accaaaactc aatttactga tataacaata cgattactaa gtaatgtgat
   983521 tactcgctat aagtaaaata tcaataaaca cgttacatat taaaatttta aatactaaat
   983581 atttatactt tactggataa attatatcaa gccaaatcac aaactacaat cgttcatcta
   983641 tataataatc gtatttaaat cataaatttt atttaataat aaaaaccaat atagtgtttt
   983701 agtatcaata ctacttacca tatctggata taaccaccat accaaactcg aataattcaa
   983761 aaataaatac acaagtattt taactatcaa caataaccaa ttataatatt aactatatat
   983821 tcaatatcct atctaacata taacaatgtt agagaatttg aaatagtttt tagttatttg
   983881 aagtatcttt tatccattaa gatgaagatg aaatacattt ttcacctaat ttatgtgtct
   983941 taactaatta tttaccaact tattgcaaat atgtttagaa taattttaac aacattctaa
   984001 taaacaatat cactaacaaa acttttatcc taaatcaaca aattaaccat tgtggcattt
   984061 tttagataag agtataaaaa caatacaata ttataatact aaagttctaa caagataaca
   984121 aacacaaggt cagagaatta aattatggta gaattgcaag attttatctt ataagatatt
   984181 tcattatgaa gcaaaagaga acctttcaac caagtgttat taaacgtaaa cgtacacacg
   984241 gtttcagatt aagaatgaga acaaaatcag gtcgcgctat tattaatgcg cgtagaaaaa
   984301 aaaagcgtaa gcgtctagca gcttaactaa tttaagtgtc ctttagacta acacgcaatt
   984361 taagagtttt aaaaccattt gactataaaa ccatttttaa acatggaaaa ataatcaaag
   984421 ggcaatactg gcaagtttta gcacgaaaaa ttgatactcc agagcctcgc ctcgggcttg
   984481 ccatttcaaa aaaagttcat cgtctagcca ttgatagaaa taaaaccaaa agaattgcac
   984541 gcgaaacttt tagaacacac caaaatgatt taaatcattg ggaatttata gtaatggcag
   984601 agcattcaaa acccgctaaa aattctataa tgactaatga tttgctacat ttattcaaaa
   984661 aaataatcac ctattaatgt attatttact cttaattcta attaaatttt atcaactatt
   984721 tatcagtcct ttgttaagct ctaattgtcg ttttcaacct acttgttcac aatatgccta
   984781 tgatgcaatc caaacacatg gcttttttaa gggattaagt cttagtttaa aacgtattag
   984841 caagtgccat ccatggcatg atagtggatt tgaccctgta ccaaaaaaat aatccccctt
   984901 taattaataa tatgaacaat caaaaattct ttctcattat tgctattttt ttaagtattt
   984961 tcctcttgtg ggacaaatgg gagataacac atacaataga taaaaataat aacctgatta
   985021 gccaaaccaa gattaaaaat actagcacga taaataattc attaacaaat caaaacctag
   985081 atataccaag tgttacaaat cgtaataata aattagacct tcctaatact gatacaaaaa
   985141 atcagatccc atttacaaca gtcaaaaccg atttacttac tctagaaatt agccataagg
   985201 gtggtactat ccaaaatgca tggctaaacg attatccaat agaaattgat tctgaacaaa
   985261 aattccaact acttagtgat agaactggta aaatattcca agcccaaagt ggcttattgc
   985321 cacaaggaaa aatgcctact caccattcaa tatttagttc taaaaatatc tattatcaaa
   985381 tggatggcaa taatttagtt gtacccttta cttggaaaag tgaaaatggg atcatagtta
   985441 ataagagata tcactttaac aaaaatagct acgtagttgg tattgattat caaataacta
   985501 acactactaa taacacatta cacataacta gctacacaca attaattcgt aatatacctg
   985561 atcaagataa catgataatg ccaacttata caggtggtgc aagatttaat gatcaagatg
   985621 tttatgaaaa aatagagttt gaagactttg atgatcaacc aaaaaccagc tacaaaggcg
   985681 gatggatggc aatgattgaa cattacttct ttgtagccgt aattccaaat ttaaaccaga
   985741 tacatactta ttcttcaaag attatcaatg ataagtattt attaactgtt gtaaacccag
   985801 aactatcaat tgcgcctggt gcaacaaaaa ccataataaa tagtaatctt tatatcggac
   985861 ctaaagaaca atctcatatt gacaatgttg caccaggttt agataaaact gttgattatg
   985921 gcatattgtt tattattgcc aagccattat ctgaattact taattggatt tattcaataa
   985981 ttcattcttg gggttattct attatcatcc ttactttgct aatcaaatta gcattttata
   986041 aactcagcga aaaatcatac cgttcaatgg caggtatgcg acaacttgct ccaagattga
   986101 aaaaacttaa agagacctat ggtgataaca aacaaaaact aggtaaaaaa accatggaat
   986161 tatacaaaaa ggaaaagatc aaccctgcgt ctggttgttt acctatctta gtacaaattc
   986221 ctgtatttat ctcactctat tgggtactat tagaaatggt tgaattacgc caagccccgt
   986281 tttggtattt aactgattta tcagcaccag atccatatta tatattacca cttatcatgg
   986341 gtatttcgat gtttattcaa caaaaactaa atccccctcc acccgaccca atacaggcaa
   986401 aaattatgat ggcattgcct tttgtattca ctatcttctt tttatggttc ccttctggat
   986461 tggtgcttta ttggatgatc aacaatatct tatcaatcac tcaacaatgg gtgattaata
   986521 aacgcattaa caactaaaaa ttattatgtc cattcttaat aatttagatg aatataaatg
   986581 ttggagagat gataaattag caaactctaa cactaatatt gaaacctgtt taattgaaat
   986641 taacaatcct ttcaagatta taaaatcaga aaaagataaa attaagcttt tatgccaaaa
   986701 aaataatttt gccttatttc atattaaaca acaaaacaac tatccaagag ctattatcgc
   986761 tatgaacaaa cagcttggat tagtagatta tgattcacat ttatacgttc taaatcaagg
   986821 tttagcgaat attaccaaga acgttaaaaa agaccaagct aaatttattc catacaccga
   986881 taaagccatc ggctggcaca cagatggtta ttacaacaaa acagatcaac gcatacgagc
   986941 attttcttta ttttgtgtca cgcctgcaag ttatggtgga gaaaataagt ggattaacca
   987001 acaaatagtg tacttacaac taagagaatc taatccagat gttgccatgg ctcttactca
   987061 tgcccaagcc atgagtatac cagaacacgt tataaacagc attgttaaac gtagaacttc
   987121 tataggtgca atttttttta ttgatcaacc aacctcacaa ctttatatgc gttatacgca
   987181 aagaaaaaaa aatattattt attcaaattc ccaagaagtt agacaagcta ttaccgtttt
   987241 agacaaatat ttaagaacta ccactaaata tcacttcagt catacaatgg atgctaatca
   987301 aggtatatta tgtaataata tcttacataa gcgttctgca tttactgaca acccaactaa
   987361 tccaagatca ctactaaggg gtcgttactt taatcgatta aattagagtt ataatttaca
   987421 tgttaattaa taatcactaa ctggaaaaag ctaaacaaat tagtttaaca aattttaatc
   987481 aacagcccaa tcaaatcatc tctttaatca ttattcacag tatttcatta ccgcctgaaa
   987541 agtttgataa tcactatatc taagattttt taacaaccaa ctagagactc atcaacacac
   987601 ttattgatta aacgcaacgg cataataatt caatttatac cctttaatca aacaggctta
   987661 gtatgtaatc tataaaataa agcataacta caatgacttt tatgaattac aaggaaacaa
   987721 caatatactg tatgaatcgg tacaatatga cattttaaat aagatagtaa agttactaaa
   987781 atataattat ctaataagtg tcgttaaaga tcatactaca tgcaattatc taataaattc
   987841 tatttaaagg ctaaaaacat aaaactgatt atttttgatg tagacggcgt actaacagat
   987901 ggtggcttat atttctctga caaaggtata gaacttaaac gctttaactc tcttgatggg
   987961 ttaggcatta aactactaaa acaaaacggt attgaatctg ctattattag tgctagaagt
   988021 tccaaaaatg taatgtatcg aatgaaaaat ctagacatta aacatttcta ccaaggacaa
   988081 gataacaaaa ttgttgcttt taataatctc atcaagaaac tatcactgaa aactgagcaa
   988141 gttgcttaca taggtgatga cataattgat ttacccgtta tgagaaaaat tggtctgcca
   988201 atcgctgttt cgaatgctca tgaactagtt aaaaaaaatg cttactttat aactaaaaaa
   988261 ataggggggc acggagcagt aagggaagtt tgtgatttat tactacaatc tcagaatact
   988321 tacaataaaa ctatggataa atacctaaca taataccatt ttaacagaaa tgctaccaaa
   988381 ctagttttta ctgaaaaaat catcaaaaat tctaccatac ttatataaca aaagattttt
   988441 gctatcgcgt aattaaacaa aatagagatg taggtaaatt ctacagaaga caatctacca
   988501 aaaaaggtat tacaataaca aaataattta ttttcataaa aagtcattaa tatataaacc
   988561 acatgacact aattgttata ccttagtttg agaaaatttt ataataagcc aaaatcttgt
   988621 ataaccgtag cattaataga ttttttatat tctatattta ttccaatttg gaaatcatcc
   988681 aaatttgtta agcaacttct aaaacaacaa accaaattac ctataagtaa agattcaata
   988741 aatagagttt tacagactat tactttcatt tgtttctagt attacaaaca acaatagttc
   988801 taatcagaaa tcttctttaa tgattctatt gagactttaa tcagttatct gctagtaata
   988861 aataatcatt ttgattttac ttagttactg ttgtattaca atcttcgtta atagaaaaat
   988921 caaaacataa atactaaaaa taatattttt tcaagtatca tcattttcaa cactttttac
   988981 cacgcatttt gttaatcatt tgcaattgtg ccatggactc agaaagtgct gcttgtgttg
   989041 ctgaaatatc ttgagtatcg attgaattat ccatttcatc ttgcgcacgt tgtttggcct
   989101 ctaatacctt aaattcatct aagtcatttg ctctaattgc agtatcagaa aaaatagtaa
   989161 caacatctgg ctgaacttct acaattccac cagaaacata aattgactct atgcctttat
   989221 cggtttctat tctaacttca cctggtttta atattgataa aagtgccgta tgttttgggt
   989281 aaatacccag ctctcctgta gatgcaggag caaatacaca caatacctca ccagaataaa
   989341 gagattctgt tgcactaaca acatcaacat gaatggtcga catttatgcc ttctccttag
   989401 atcttccacg aacctcatca attgagcctg tcatataaaa tacttgttct ggaaaatcat
   989461 ccatttcacc atcaagaata gctttaaatc cagcaattgt atctttaaga gatacatatt
   989521 ttcctggtgc accagtaaat acctctgcta caaaaaatgg ctgagataaa aaacgttgaa
   989581 ctttacgagc acgagatact gaacgcttat cttcttcaga tagctcatcc attcctaaaa
   989641 ttgcaataat atcttttaat tctttgtaac gttgcaaaac tccttgtacg ccacgagcta
   989701 cattataatg ctcttctcct acgattaacg ggtctagttg gcgtgaagta gaatccagtg
   989761 gatctaccgc aggataaatg cctaattctg ctacttgacg tgataataca actgttgcat
   989821 ctaaatgagc aaatgtagtt gctggcgatg ggtctgttaa atcatctgca ggtacatata
   989881 ctgcctgaat tgaggtaatt gaaccttttt tagttgaagt aatacgctct tgtaatgcac
   989941 ccatctcact tgccaatgtt ggctgatatc ctactgctga tggcatacga cctaataatg
   990001 cagatacttc cgtacctgca agtgtataac gataaatatt atcaataaac aacaatacat
   990061 cacgaccttc atcacgaaag tattctgcca tagtgagtcc tgtcaaagca acacgtaatc
   990121 tgtttcccgg tggttcattc atttgcccat ataccaaaga tactttatta agtacatttg
   990181 actctttcat ttcgtgataa aaatcattgc cttcacgagt acgttcacct acaccagcaa
   990241 acactgaata accagaatgc gcaatcgcaa tattacgaat taactccatc atattaacag
   990301 ttttaccaac accagcaccg ccaaataaac caaccttacc gcctttagca aatgggcaaa
   990361 ttaaatcaat caccttaata cctgtttcta ataattctgt tgtaggtgct aattcatcat
   990421 aatcaggggc gcttcggtgt atagtccagt caacctcctg accgatttca cccgcattat
   990481 caattggctc accaagtaca ttcataatac gccctaatgt cttgacacca acaggcactt
   990541 taataggttc acctgtatta gtgactccta ggcctctttt taggccttca gaaccaccca
   990601 tagcaattgc acgtactata tgatctccca gctgctgctg aacttctaag gttaagcctg
   990661 tttctaaaac ttttaaggca tcataaattt ttggcatatt atctgctgaa aattcaacat
   990721 cgataaccgc accaataatt tgtgtaattt ttcctatact cattttgctt ttcctttttt
   990781 aaactttaaa cagctgtagc accaccgcta acaatctcag aaatttcttg cgtaattgcc
   990841 gcttgccttg ccttgttata aatcaattcc aactccttaa ccatatcacc tgcattgtcg
   990901 gtcgcacttt tcattgcaat catacgtgaa gattgctcac aagaaatatt ctcaaccaaa
   990961 ccttgataca ccaaagcctc aatataacgt actaataacg cgcttaaaac ttcttgtgca
   991021 ttaggttcat aaatatagtc ccaataatga tttatattgt ctgatttaat tgatactatt
   991081 ggcactaatt gcataattgt tggtatctga atcatggtat tttcaaattt attataagca
   991141 actgataatt gctgtatttc acctaaatca aacccatcaa gcatgatctt aatcgttcct
   991201 aataagtcat caaaatgggg tgaatctcct aaatctgtca atacagattt aacatttaaa
   991261 ccaaagtttt taaaaaataa agttgctttc ttaccaatcg tgcaaatgtc aactttaata
   991321 ccattagctt gatattcaac aacttgcctt aaaatatatc taaataagtt agtattcaaa
   991381 ccaccacaca aacctctatc actcgaaata ataataatac caatgctctg aagtttttta
   991441 agactattca tataaggatg ttgaaattct gaatgcgcat aagctaaatg accaataata
   991501 ttagaaattt tctcacaata aggtcgtgat tctaacattc tatcttgtgc ttttttcatc
   991561 ttagaagctg ccaccatttc catagctgaa gtaatcttct gagtattttt aatacttgaa
   991621 atttgcgttc taatttcttt tccaactgcc attatctacc ttattctacc aagtatagtt
   991681 tgttttaaaa tcatcaattg ctacttgtaa ttcatttgaa atcttatcat tataattacc
   991741 tatttcatta atcctattca ttaatgatac ttggtttacc ttcatataag caattagtga
   991801 tacttcaaaa tcaactattt tatttacctc aatatcgtct aataaacccg aattagcaga
   991861 aaacaataaa gtcgccattt cagcaattga taaaggtgaa tattgatttt gcttcattaa
   991921 ctcagtaaca cgctgaccac gatcaatttg agctttagtt tctacatcaa ggtcagaaga
   991981 aaattgtgca aaagccacta attctctata ttgcgctaaa tcaagacgaa tgccaccgcc
   992041 taatttttta ataatattgg tttgtgctgc accacccaca cgtgatactg ataaacccac
   992101 attaatcgct ggacgaatgc ccgcattaaa caaatctgtt tctaaaaaaa tttgaccatc
   992161 tgtaattgaa ataacattag taggcacaaa tgctgacaca tcaccacctt gggtttcaat
   992221 aattggtaat gctgttaaag aacctgtttg tcctttaact ttaccattgg tcatcttttc
   992281 tacataatct gcattaacac gtgaagcacg ctcaagtagg cgtgaatgta aataaaatac
   992341 atcgcccgga taagcctcac gtcctggagg acgtttaagc aacaaagaaa cctcacgata
   992401 agcccaggct tgtttagtta aatcatcata aacaatcagt acatcttcac ctcgatcacg
   992461 aaaatactca gccatagcac atcctgcata aggtgcaata tattgtagag ctggagaaac
   992521 tgcagcacct gcaacaacaa taatagtatt tgccaatgca ccatattctt ccaatttacg
   992581 tacaactgta gctactgatg agtctttttg accaatagca acatatacac aacgaatacc
   992641 actgtctctt tgattaataa ttgcatcaat cgctaccgct gttttacctg tttgacgatc
   992701 accaataatt agctctcgct gaccacgacc cactggcacc attgcatcaa tcgctttaat
   992761 accagtttga ataggctgat ctactgattt acgatcaatc acgccaggtg ccattacttc
   992821 taacggacgt acgccttgag catcaatatc acccttaccg tcaatagcct tacctagagg
   992881 attaactact ctacctaaca tagcctcacc aacaggcact tcaactaaac gattagtaca
   992941 tttaacaata tcaccttcta aaatatgtaa ataatctcct agaataactg caccgacact
   993001 atcttgttct aagttaagcg ccataccaaa ggtattattt gaaaattcaa tcatctcacc
   993061 aaattgtaca tcgcccaaac catgaatacg gacaatacca tcactcacac taaccacact
   993121 accctctgta cgtgcctcag cggtaaaatc aaacccttct atttgctttt taattaaatc
   993181 actgatttca tgagcgttta attgcatagt aattcctctt taaattctaa taattagtgt
   993241 gtttttgata aacgcaaacc tagctcgtcc acccgagctt ttattgagat atcaataact
   993301 ttatcaccgt ctttaataat aacaccacct actaaatctt tatctacgac aatgtcaatg
   993361 cttactgttt tattatattg attcattaaa tcgcttacaa tttgttcttt ttcagattta
   993421 cttaactgat aagaactaat gatagtaaat attttaatat tatttgttat gttaatcaaa
   993481 ctttcaaaca aggttgcgat acttggcaaa ataccaatac gattattatc taataacaca
   993541 ctaataaaca tcgcttcatg cgcgtctaat tctctattta atattgacat aagcaatgct
   993601 ttaatagtac ttaatttatc ttgttctaaa atattaggag aagcaatcaa tctacgcatc
   993661 ttcttatcaa gaagtaaata cgctcctaca tctaaaacca tcttccactg taaatgcgaa
   993721 ttatcctgct gtgctaattc aaaaattgca ttagcgtaag gtttggcaat aacagctaat
   993781 ttcatagcta attacgacag tgattctgac aatttaccta acatttgttg atgtaactta
   993841 acatcaacct ccttatcaag taccgcatta acaccttgta taaccaaatc agacacttga
   993901 ttctttagct cattacgaac acaaattgta tcttgttcga gctgcgcttg cgcttgctcc
   993961 tttaccttac ctgcttcttt taaggcgata tattttgcat cttcaaccat atttaatgcc
   994021 tgacgagtag catttgcaat aatctcagcc gctagacttt tagattgatt aataatttcc
   994081 ttagctttaa tttgcgcttc tgctttctca aaacgaccac gctctgctgc taataaacca
   994141 ccttcaatac gtttttgacg ctcttccata gccattacaa taggtggcca aataaacttc
   994201 atacaaaacc aagtaaacat ggcaaacatg attaattgtc caaacattgt caaattaata
   994261 ttcataactc agtccttgca tttcaaatca tttttttatt ttatcctgca accgcaaata
   994321 aaatatacat tgagatgcca acggcaatca ttggtactgc atccaccaaa cccatcacaa
   994381 taaacatttg tgttctaagc attggtatta actctggttg gcgcgccgct ccttctaaaa
   994441 attttgcacc taaaatacca ataccaactg ctgcacctaa tgcacccaaa cccattaaaa
   994501 ttgaacctgc taaaaataaa atactttgtt ccattttttt actcctattt ataaaataaa
   994561 attaatattc cttttgatgg gccatatcca tataaacaat gaccagagtc ataaaaataa
   994621 atgcttgtaa taatacaatc aaaatatgaa aaattgccca cggtaaagac aaactccact
   994681 gaatccaaaa tggtaataaa gcaataagaa taaaaatcat ctcccctgca tacatattac
   994741 caaataaacg taatgctaat gaaacaggct tggcaattaa gttaactcct tctaaaaaca
   994801 aattaaacgg caacatcatt ttaccaaatg ggtggaaagt taattctgct acaaaaccac
   994861 ccattccttt ctccttaatg ctgtaataga taatcagaat aaaaatacca attgacatac
   994921 caagagtcgc atttagatct gtagttggta ccactttaaa gaaaacatga tgtagatcag
   994981 caccaaacca aactccgatt ttctgtgcaa tgtatggcaa ccaatcaact ggtaccaaat
   995041 ccatagcatt cattaataca atccaaataa aagtagtaag cgctaatggt gcaaccatag
   995101 gattttgacc attaaacgag ccacgaacgt tttcgttaat ataactaatc acactttcaa
   995161 taaagttttg tgcccctgaa ggagtatcat aagtcatttt tttaccaatt cgataaaaaa
   995221 agctcaaaaa taacataccc aatacaaaag atatgctcaa tgtatccaaa tgaacagcta
   995281 aaaaacccat ttcttttgct tgttcagaag tatgtgcaaa cccccaataa ccatctggaa
   995341 attgaccata cgtcaaattt tgtaaatggt gcttaatata gctaccagaa gttatgactt
   995401 catttgtcga tgacattacc tatttataac cctgtctatt aaaaaaccaa tctgccccaa
   995461 aaccaaacca ataattaatg cctctggtgc caaccctata atcaataagc caaaaaaagt
   995521 caataacact aataaagtca tacgcataat aacactaact gacatcatta taacgtcaat
   995581 acctggacta atatttaatt tccctttttg tttatttgta tgcctattaa tcaaactagt
   995641 gtttaatagg ccaattatgc caccataaat tgctgctata gccacattgt tcatggagaa
   995701 gtaaatactc accatcaata acgcacttaa ttgtaccttt ggccattcac ttcttgttgc
   995761 caaaatatct attcgcctaa tcgaatttac aaagtttaaa ttatacagtc tagcttataa
   995821 aaaaatcgct tttttatgac ttccaatcaa ataaattact tcttaactaa atatgattat
   995881 ataagcatat tgtgatacat ttgacaagta tgcgtattat cagaataatt aacttatttt
   995941 taggagagat tatatgtctc atgttgttgt tataggcgca agcacaggcg gattgccttt
   996001 tgcttacgat attaaaaaaa cattaggaaa agatcatcag gtaacggtta tttccaataa
   996061 tccaaacttt aactttatcc cttcaaaccc ttggttagct gttggttggc gtagtgaaga
   996121 gaatattagt tttttacttg aacctcattt aaaacgcaaa gatattgagc ttattattgg
   996181 cgaagctagt gaaatcaaac ctaatgacaa ccaagttata gttggtaacc aagttataaa
   996241 ctatgattat ttagtgctag ctacaggacc taaacttgct tttgacgaga ttgaaggttt
   996301 aggtcctgaa ggtcatagtg tttcaatttg cactactgcc cacgctgaat cagcacgcca
   996361 agaatggaaa aagttttgta caagtggtgg tggaccaatt gttgtaggcg ctgtacaggg
   996421 tgcctcatgt tttggtccag cttatgaatt cgctaccatt atggatactg atcttaaaaa
   996481 acaaggtatt cgtgacaaat gtcctatcac ttttattacg gcagagccat atattggcca
   996541 tctaggattg ggtggtgtag gtgactcaaa aggtttatta gaatcagaat ttagacaacg
   996601 tcatatcaag tggattacta acgctaaagt tactaatata gcaactaata aagttacggt
   996661 agatcaagtt aatgatgaag gaaaagtagt taaaacaatt gaaatagcca ctcagtacac
   996721 tatgatgttg ccagccttta aaggtgttga tatagttgca aaattagccg atatagatac
   996781 aggttttgtc aatccccgtg gatttgttat tgtaaatgat tatcaacaat ctcctgttaa
   996841 agataatatc ttttcaatcg gtgtaaatat tgctattcca cctgttgagg aaacgcctgt
   996901 aatgtgtggc acaccaaaaa caggttacat gattgagtcc atggtaaccg ctgttgtaca
   996961 taatattgaa gaaatgattg ctaataaagc acctactcat atcccaactt ggaatgctgt
   997021 ttgtattgct gacatgggtg acacaggtgt tacctttgtc gccatgcccc aaatccctcc
   997081 cagaaacgtc acctgggcca aaaaaggtaa aatgatgcat cttgctaaaa tcgcctttga
   997141 aaaatttttc attcgtaata tgaaaactgg caattctgaa cccgcttacc aaaagtacat
   997201 ttttaaaata ttaggaattg aacgtttaaa gaaaaaataa gtttttaaaa attaatagtt
   997261 aatcaactta gaagatcgct atgaaattca caagcacata atttcttaaa gtgtcagaag
   997321 atagaaataa gttgttagat tactttttct aaaagttctg tcgctagtgg ttgccgctag
   997381 gttgactaaa ttttaaaagg tatgtcggat aaagtttata caaaggtttg taattaatag
   997441 cttgaacata taatattgaa tatacaaaaa caactcataa aatattctga ttataaatat
   997501 gctatatccc tgtcaaatag atcacactca tataataagt cagaacactc ataagataac
   997561 taaaatatat gactactaac catgaattat aatgaaaaat tacctcaaaa gaaccatttt
   997621 agaaaactac taacacatca aaattcaaat attagataat cattttaatt tcatccatat
   997681 aattcattat tagataactg tattaactac taaattgaaa aaaacataaa atgtcttgta
   997741 tattgatata tataaggatt ttaaattatt agatcttaag ccacaccatt aactttaact
   997801 tcagattaat ccgcactaaa gtagtacaat aatgactacc taatatcaat attaaagcta
   997861 gacttacacc agcctgtttc atttataaaa acgctcttat ctcacctaaa aaaatctaac
   997921 atttcaacaa cctaaaaatt tttaatactt aactaagaaa catcgactaa agtttgtgac
   997981 cccaatgtaa tttagatcga ataatctcaa aataattata atccttaggg tgtaataaat
   998041 taataaaact actgtgctga cgcacacaaa tatcttgacc aactttgata acaatcgagg
   998101 tttgcccatc aaagctaaca atagtaccat catctgaatc tttcacttga atcataactt
   998161 cactatcacc tggaatcaat aaagggcgat gactcatggt atgtggacaa attgacacta
   998221 aaccaatagc attaacacct ggatgcataa taggcccacc acttgataat gcataagcgg
   998281 ttgatcctgt tggtgtggta ataatcaaac catcggcacg ctgattatta acaagtttat
   998341 tatcaatata aacatcaaac tcaaccattt ttaaatgttc tttccgatga ataatcacat
   998401 catttaatgc taaaaaatta tctaatattc tattattttg ttttatttga caagacaaca
   998461 aacaacgttc ttctttaata tacttaccat ccaaaacttc tgaaacaata tcaaacatac
   998521 ctgttaacga cacatcagcc aaaaaaccca accgtccaag attaatacct aaaataggga
   998581 tgttattgtc aacaaaacta cgtgcagtac taagtatcga accatctcca cccacaacaa
   998641 taatcaagtc tgcttcttga ataatacttt tattcccaga tactacatct acgtgatagg
   998701 ttaataaaaa ttcactcaat ttaatagctg tgtcttcact cacagaatca ttgggtttag
   998761 taataatacc aattgtctta aacatatttg ttaatcatta agattaaatt ctttaaaata
   998821 gtcatttata gtaaataata attaatttat tttatagata atttcattta ttatctataa
   998881 atcaatattt ttaacaaata tacatgaatt gagcaacaaa atgacaaaaa agaaatcaga
   998941 aaaaaagaat caagaaagag cttcagtaga aaaaaaagat attgaaacca ctactaaagt
   999001 tgacttgcaa acaccacaag atgaggattt acaagaacaa ctagcccaag cgcaacaatc
   999061 tgctaaggat aattgggaca aacttttaag gtctcgagca gaaatggaaa accttaaacg
   999121 ccggaatgct aaagatgtcg aaaatgcaca caaatttgca ttggatcgtt ttgtcaaagc
   999181 attacttgaa gtgaaagact cattaagcat gggtattaaa actgcacaag aagaaaaagc
   999241 aactgttaaa catattgtgg aaggattaga aatgactgat aaagtttttc tatcaactct
   999301 caaaaaattt ggcgtagaaa tgattaaccc tgaaggtgaa acttttaatc cagaattaca
   999361 cgaagctgtc accatggtac ccatgacaga caaagaccca aattctgttt tagaagttgt
   999421 acaatttgga tttactttaa atgaacgctt agttcgccca gcaatggtcg ttgttgttca
   999481 atagacaaca aacttataac tttacaaaaa ttagaggatc cttaaatgga tactgataaa
   999541 ataaaataaa ataaaataaa ataaaataaa ataaaataaa ataaaataaa ataaaataaa
   999601 ataaaataaa atacatgaca aactttttat attagtatta cacatactaa gattaggctt
   999661 gattgaacag ttaacaacta tatttaaaat aatttaatac caatatatat tacacatgtt
   999721 gctgctaagc tactttaacc aactcaatat tactattact ctaacttagt cgaatagtct
   999781 actgataata tatccctaat tgataataag attagtgaaa caagaagaca gagtaataaa
   999841 catatgttgt taattttatt taaataaata ttcttattat gagcaaatag taaaaaactt
   999901 attcaataaa atttcaacgt aatctctatt aatattggaa ataataaaaa ctagtctttt
   999961 aagttaagag tgaataataa cataaatcaa aatgcaatat aaactaacac tgatttcttt
  1000021 aaatcaaaag aagtaatagc ataagataaa agactattga aaaattgaaa aaaaatattc
  1000081 aaatatacac atacaaacaa tatacaaaat taactttaga acaatatatt aagaataaac
  1000141 taacaattat aaaactatga tattctttaa aaaatgacga tttctatatc tttgtaactc
  1000201 gattaaccat aattataaaa ataaaagttg caatacttac gattattttt ttaacaacaa
  1000261 atccaaaaac aagtctatct ttaattaatt taactccttc tagtgtagca cattatgata
  1000321 cctatctata aataatccat tattaatata aaaacaacca aatcacacct ataaatgaaa
  1000381 taaaagaact aaaacttaac tatccacctg gcattgtttt atttaataaa gatgataaaa
  1000441 tcactagtat ttatagatat aaaacttcca ttttcaagaa atattgatat tcgtaaataa
  1000501 tatttacttg ttataattaa gcatacaata tattaaaaat tgcaattgat tcttctataa
  1000561 aagaaacatg aaacgtttac taatatcctt aattttaata ttatccacat ttttattagc
  1000621 acaagtagaa aatgatttat tgccagtaaa caaagcattt atctttaaag ctgaagtagt
  1000681 taataataaa atattactta attggaaaat taagaaaaat tactttcttt ataaagaaaa
  1000741 aattaagatt tatgctgatt tttcagcaca actaggtaat gccaagtttc caaaaacaaa
  1000801 gattagaaat gatgaatttt ttggaaaaat tgggatttat cgtgataata ccatagtagt
  1000861 tgtacccatc cttaaagggg gagctaaatc tattttatta accgttaatt atcaaggttg
  1000921 ctctgatttg ggtgtgtgtt accctcctat tactaaatca gttgtgcttg acattagttc
  1000981 aatacattca acttccttgg ataataattc atttaatctc ttatcacaag caactaacaa
  1001041 agtgcaatca cttgttaaaa acagcatacc aacttctaat aagcctttgt ctgtagataa
  1001101 tgcatttaaa ttttcagtag tagcaattaa taacaataca ctactagcta aatgggatat
  1001161 tcatcaagaa tattatttat atcataataa atttttattt gatattaaag gagcaacatt
  1001221 tggtaatatt gtgatctcta aaggtaaaat taaagacgac aagtttcttg gtaaaattga
  1001281 ggtccacaaa gatgcattag aagttgaaat tccactcact gatattaata ctaaatcaat
  1001341 tactcttatc attaaatatc aaggatgttg ggaaggtggt gtttgttttt ctccacaaga
  1001401 aaaaaccata aatattatgt taccttctca aacaaacaat cctaaaatta atgctttatc
  1001461 taaaaaaaaa tcaatataca cacctaatat tgttcagatt gaattgaacg aaactgatca
  1001521 aattactgcg ctatttcaac aagaaaacat attgttagta ttagcaagtt tctttggttt
  1001581 tggcttattg ttatcattaa ctccttgcgt atttccaatg attccaattt tatcaggcat
  1001641 tattgttggt caaaaagaag aagtcagtac taaaaaagcg ttaattatgt ctattgtatt
  1001701 tgtactatcc atgagtatcg cttactcaat cgtgggtgta tttgcaggtt attttggtga
  1001761 aaatttacaa gtattattcc aagatccttg ggttttgtct atttttagct tgatctttgt
  1001821 tactttagca ttttctatgt tcggctatta tgaaattcaa ctacctacca gtttacaaga
  1001881 aaaaattaca aaaattaaca atgatcaaaa gggaggacac ctaattagtg tagctattat
  1001941 gggtttttta tcagcactga ttattggacc ttgtgttaca ccaccgctag caggtgcatt
  1002001 aatttatatt ggacaaactg gcgatgcatt attaggcggg atatcactat ttataatgag
  1002061 tctaggtatg ggttcactac tcattatagt tggtgcaggc gtaagcaaat tacctaaagc
  1002121 agatggttgg atggaaagta ttaagtacat ctttggtatt ttaatgttag ctatagcaat
  1002181 ttatctactc gatagaatta tctcacccct tacttcactt atcttgtggg caatgcttat
  1002241 taccatatca ccaattgcaa tgggtgcatt aaacacacaa ataaacacct caaaaccttg
  1002301 gcagcgtatt tttaaagctt taggattgat tatactaggc tatggtattc tactttggat
  1002361 attagtagca cgtgggggtg gtgatatgtt acaaccacta tctagctgga gatcatcaaa
  1002421 tatagaaatt gaatcagacc atttaaaatt taaacaaatt aaatctataa gcgacttaga
  1002481 acaagtttta atacaaacta aaaacaataa ccaaattgtt atgctagatt tttatgctaa
  1002541 ttggtgtacc tcttgtaaag aacttgaact ttttatattt tccaataccc atgtagtcaa
  1002601 tgagatgtct gacgttattg cactacaagc tgatgtaact gaaaataata tcaatgataa
  1002661 agccttaatg aaacgattca acattgtggg accccctgct attttatttt tcaaaaacgg
  1002721 tattgaaaat cgctcacaaa gaattattgg agaaatcaac acacaaaact ttcttagtcg
  1002781 tcttaacaaa attaaataaa acaagccaaa acgctgttag aacttactat cttgcataat
  1002841 attgatggta aaatcatctt tatttttatc tttgcttatt tgaataaatg gatgttcttt
  1002901 tattaaacgg acctaacctt aatctgcttg gttctcgtga acctgactat tacggtacac
  1002961 aaacattgga tgacattacc agtaatctta caaaaatagc aaataatgtt ggtctgacgt
  1003021 ttgaacacca tcaggataat tcagaagcaa agctaattaa atatattcac aatgctgtcg
  1003081 ataacggagt tcaatatata attattaacc ctgcagcttt tacacacaca tcaatcgctt
  1003141 tacgtgatgc tatacttgct gtaggtattg aatttagtga agttcacttg tctaatatat
  1003201 ataagcgtga aaattttcgc aaacaatctt atttttcaga tattgcacaa ggaatcattt
  1003261 caggctttgg ccctcagggc tatgaattcg cgctacaagc tgcaattcaa catattcaac
  1003321 aattagagag gttgtaaatg gacattcgta aagtaaaaaa attaatggaa ttactggagc
  1003381 aatctagtat gagtgaaatt gaaattgttg agggcgaagg atctctgcgt atctcacgct
  1003441 atagaaatgc tacaatggca ccaccagtag caattacaac tccagtagta gcaccaatag
  1003501 aagtcactac aggagtaaat ccgtctgaaa ataatatatc cacagtagat ggccatccaa
  1003561 ttacctcgcc tatggttggt actttctata gcgcagcatc acctaattct gatgcttttg
  1003621 ttaagattgg tcaacatgtc aaccaaggcg atacaatctg tattgttgag gcaatgaaaa
  1003681 ttatgaacca aatcgaagca gaccaatctg gaacagtaac tgaaatatta tgcacagatg
  1003741 gtgatgcagt tgaattcagt caaacactgg tcatcattca atgacatcaa tgaacaaaat
  1003801 tagtaaggtt ctcatcgcta atcgtggtga aattgcactt agaattttaa gaacttgtaa
  1003861 agagctaggc attaaaactg ttgctgtata ttcaacagca gataaagatc ttaagcatgt
  1003921 tcgcttatct gacgaggctg tatgcattgg tcctcatcca tcaaaagaca gttatttaaa
  1003981 catcccagca ctgattgctg cagcagaagt tactcatgct gatgcaattc atcctggtta
  1004041 tggcttctta tctgaaaatg cagattttgc acaacgtgtt gaagaaagtg ggtttatttt
  1004101 tatcggaccg cgtgctgata atatccgtac aatgggcgat aaagttgctg ccattaatac
  1004161 catgcaaaaa tctggagtac cttgtattcc tggatcaaat ggaagtttga ctgaagacgc
  1004221 cgctcaaaac acccaacttg cacgtgatat tggctttcca attataatca aagcctctaa
  1004281 cggaggtgga ggacgtggca tgcgtgtggt tgaaaaagaa gctgacctaa ttgactcaat
  1004341 tgaaatgacc aaaacagaag cgcttaactt ttttggcaac tgtaaagtat acatagagaa
  1004401 gtttttaact aaacctagac atattgaaat tcaaatatta gctgacgaat acggtaacgc
  1004461 catacactta ggtgaacgtg actgctcaat gcaaagacgc caccaaaaag tcgtagaaga
  1004521 agcgccagca cctggcatca caccaagatt acgtgataaa atcagcagtg cttgtacaaa
  1004581 tgcttgtaaa gccattagtt atcgtggcgc tggtacattt gaatttttat ttgaaaataa
  1004641 tgaattctat tttattgaaa tgaatacccg gattcaggta gaacatcctg ttaccgaaat
  1004701 gattactggt attgatattg tgcgtgaaca aatacgcatt gctgacggtc aaatactatc
  1004761 attcacacaa aatgaagtac acgttaaagg tcatgcgatt gaatgtcgta ttaatgccga
  1004821 agaccctaat aatttcatgc cctcaccagg aaagatcacc caataccata tagctggagg
  1004881 gttaggcgtg cgtgttgact ctcatgtata taacggttat gtcgtgccgc cctattacga
  1004941 ctctatgatt ggcaaactaa ttactttttc tgatactaga ctaggcgcta ttattaaaat
  1005001 gcaaaatgcg cttgatgaaa tggtaattga tggtattaaa actaatattg ccttacaaaa
  1005061 aagaatcata gatgatgaaa cttttcaaaa aggtagtata aatatccact atcttgaaaa
  1005121 aatgttagga aattctttaa tatgatcaaa gtaggcatta ttggctctac tggatacaca
  1005181 ggattagaac ttatacgtct tctacataac cacccaaatg caaaaattat cgcactatgt
  1005241 tcaagaataa atgctagtaa atccgttatt aaagaatttc ctagtctaat aagctatatt
  1005301 gatcttgact ttgttacacc aaatgaaaaa aaattatttg aatgtgacat tattttcttt
  1005361 gctaccccac atggtgtagc catgaatagc gttagtaaat tcttaaacaa agatattaaa
  1005421 ataattgact taggtgctga ttttcgcatt aaagatagca ctgaatggag taaatggtat
  1005481 ggtatgacac atacacaagg tgatttatta aaagatgctg tttatggctt acctgaagtt
  1005541 tataactcac aaatcaaaaa cgcaacctta attgccaatc ctgggtgcta tccaaccgca
  1005601 atcattctag cactcaagcc tttgcttgaa acaaatataa ttgacacaaa aagcattatt
  1005661 gctgattgca aatcaggcgt tagcggtgca ggaagaagcg ctaatattgc cacacttttt
  1005721 tgtgaagtaa acgaatcttt aaaaccttac aatgttgatc aacatcgtca taagcctgaa
  1005781 acacaacaag ttttaaccga tatcgcggga aaagaagtga attttttctt tactccacat
  1005841 ttagtaccta tgactagagg tatgcttgct agcatttacg ttgatttaat aaaggatatc
  1005901 aacgtacaaa aattatttga aaaacactac caaaacaaca aatttattca catattacca
  1005961 actaatgttt atccacaaac aaaatcagtt aaaggcacaa ataattgcca tattggtatt
  1006021 caaaaatcga ataacaaact tatcattatg tcagttattg ataatatcat taagggtgcc
  1006081 tcagggcaag ctatacaaaa catgaacctt atgtttgggc ttgatgaagg attaggatta
  1006141 gaacaaattg gtttactacc ataaggaaat aacatggaaa taaaacaaat ttcagaaaaa
  1006201 gcagatatca tttttagtga taatgcagct aaaaaagtat caacattaat tgaagaagaa
  1006261 caaaataata acctgtattt acgtgtttat atcacaggcg gtggctgttc tggattttcc
  1006321 tatggtttta cttttgatga aaaacgtaaa gaaggtgact caagtgttac aaataatggc
  1006381 gtacaattag tgattgatcc catgagttat caatacttaa ttggtgcaac tgttgattac
  1006441 ttggaagact tacaaggtgc acgttttatt attcataacc caaatgctaa aactacttgt
  1006501 ggttgtggct catctttctc tgtataaatt atgattaaat atatccccgg cttagcaggt
  1006561 gttcctgcaa cagaatcctc catctcttcc attgatggaa aaaatggtat tttaacttat
  1006621 cgtggttact caattgaaga tttagtcaaa tacgcctctt ttgaagaagt ttctatgcta
  1006681 ctccgagatg gagaattacc agacaaaaac agattagata actttaaaga tgttttacat
  1006741 aaacgctatg aagtaaaacg taatatccac tctatgatgt ggtctttacc cgctactgga
  1006801 cacccaatga atgttttaca aaccgccatt gccgctatgg caacattcta tcctgatgct
  1006861 ggcgcacaaa atcctgattc tatttgcacg caaagtgcac taactaaaat tatttctaat
  1006921 atgagtactc tggtggcaat gtggacacgt attagtgctg gttataatcc tattccacct
  1006981 agtaaaggga tgtcatatgc caagaacttt ttatatatgt catctggaga agaacctgat
  1007041 aataatattg tcaagctttt tgatgcttgc ttaattttac atgcagaaca cacgattaat
  1007101 gcctcaactt tctccgccat ggtaactgct tctacacttg ccaatccatt tgcttcaatt
  1007161 tcagctgcag ttggcacttt agcaggttct ttacatggtg gtgcaaatga agatgtgctt
  1007221 aaaatgttag acgagattgg aaatgccaaa aatgcacgta cttatattga aaatcgccta
  1007281 aaaaataaac aaatcatttg gggtatgggg catagagaat atagtgttaa agatcctcga
  1007341 gcaaatattt tacaaaacat gattgaatct tatatcaaaa aatctaatat gcatttttct
  1007401 aaacgctttg aaactgcact agaggtagaa agagtttgtg aagagttgct atcaaataaa
  1007461 ggtatttatc caaatgtaga tttttactca ggaattgtat atgccgaaat tttcaaaatt
  1007521 ccacaaacac acttcacacc tatttttgct atggctcgct cgagtggatg gacagctcat
  1007581 tggcacgaac aagttagaca caaccgtatt tttagaccaa cacaaatcta tacaggggct
  1007641 cattttagaa gttatcctaa aaaataatta tggaaaatac tacacatttt ggatttaagc
  1007701 aggtggctac aaatgacaaa caaagtttag tgagagatgt ctttaactct gttgcaggca
  1007761 agtatgattt aatgaatgat atattatctt ttggtacaca tcgactttgg aaacattatg
  1007821 caatcacttc aggtaatatt aaaatgggtg acaaagtact tgatattgct gggggtacag
  1007881 gtgatttaac catggaattt acacgacaag ttggcgataa tggacaagtt atactcagtg
  1007941 atattaacac taccatgcta cacgagggtc gaaaaaaatt aactaataaa ggtatttttg
  1008001 gcgttgagtt tatacaactc aacgcacaat acctaccttt taaaaataac acgtttgatt
  1008061 gtgtcagcat tgcctttggc cttagaaacg taactaatca agaccaggcg cttgaagaaa
  1008121 tgtatcgtat tttaaaacct agcggttgtt tgttaatttt agaattttct acaaccaatt
  1008181 ctgtgttact aaaaaaaata tacgactttt attcattcaa aattatacca aaactcggtg
  1008241 atattattgc taacgataaa acctcatacc aatacttagc tgaatcaatc cgcaaacatc
  1008301 caaaccaaaa aactcttaaa aacatggtac taaatgctgg atttgacttt tgcgaatatc
  1008361 acaatctatc aagtggtatt gttgccttgc ataaaggcgt aaaagtataa aagacaatgc
  1008421 aactttttta gcataagaaa actgccataa ttaaaaaaac attaaatcgc ttaattacta
  1008481 acaatgaggt taacatccat atactcaaca aaaaaacaat tggtttttct ttaaaaaatt
  1008541 tacagttaaa cttacatttc atatacacta acaatcaaat atttgtctta cctgctacta
  1008601 acaaacctac aaacgtcaat attacactaa aatctatagt gtttatattc ttacttcaat
  1008661 gtaaaggttt aactcaatta atcagacaag ataaaattaa tattcatagt gattttaaaa
  1008721 ctactcaact attgattaac ctattaaaaa aggttgatat tgactttaaa gaaataatat
  1008781 caaaatacac aagcgacata gttccttatc aactagcaaa actaacgaaa aaaatccaaa
  1008841 aagttaatat acaaaaaata aattcgcttg aaatgattaa aaatagacta tccactctat
  1008901 cgatcaataa aatcaaaaca aaacgacaca aacgtaaaaa cagttggact ctatgtatag
  1008961 ctttctaaga tttattaaga tttctcgtgt tttaatgcga tatcgtcttg attctttagt
  1009021 gctatcaacg ccactactaa aaagttttaa gcctttagta tatctcattc cttggcatta
  1009081 ctttcccgtt aaaaaataca cacgaggtca acgaattcga ttagcgctag aagaattagg
  1009141 acctatattt atcaaatttg gacaaacact ttccactaga cgcgacttaa taccaaaaga
  1009201 tattggagat gaattagcaa aactacaaaa caactgccct gcatttgacc caataaaagc
  1009261 taaaaaaatt attgaacaat cactcggcga atccactgaa aatttattta aacgttttga
  1009321 tattaaacct ctagcctcag cctcaattgc acaaatacat actgcattaa caaatgatga
  1009381 caatgaagtg gtaattaaag tcgtcagacc agatatcaat aaggtcatcc aacatgatat
  1009441 taaattaatg tacaccttag caatgttatt taacaaacat caacttagta aaaaactacg
  1009501 tcctatagaa gtggtggcag agtttgaaaa cattattcta aatgaattag atatgcgtat
  1009561 tgaagccaat aactgtttaa aaattggcaa aaattttaaa aactccagcc tactttacat
  1009621 tccaaaaatt taccctaact tatgtcataa gaatattcta acaatagaac gaattcatgg
  1009681 tattccagtt aatgacattg aacaactaaa agccaataat attgacatga aacaactagc
  1009741 agaagaaggt gtgattattt tctttactca agtttttaaa cataattttt tccatgctga
  1009801 tatgcatcct ggtaatattt ttgttaatac taatgggcaa tatatgggag ttgattttgg
  1009861 catcatgggt actctaacca agacagacaa agatttctta gcagatattt tcatagcgtt
  1009921 tttcaaccaa gattataaaa aagtagcaca aatatatatt gattctggct ggataagttc
  1009981 aacaacaaac atattttcct ttgaaactgc agttcaaaga atttgtgaac caatgtttga
  1010041 aaaaccttta ggtgaaatat cttttggtca agtattgctt gaacttattc aagaagccaa
  1010101 aaattttgac atcactattc agccacaact gttattatta gataaaactt tactaaacat
  1010161 tgaagggctt ggtagacaac tatatcccca gcttaactta tggacaaccg caaaaccatt
  1010221 tttagaaaac ttggtcaaag aaaaatatag tataaaacac acctttgaaa aaatcaaaga
  1010281 ccaaactcct caactactaa aagacattcc agagctacca tctatgacta ttaatgcaat
  1010341 caaacaatta aaccaaataa aagatatagg acatctttat atccaacaaa ccaatattat
  1010401 tgttaaccaa cttaaaaaca acgaaaacaa acacacttca gccattttag ctggatctat
  1010461 gaccatcctt agcggtattt tagcagttaa tacattttgg cttccaagtt tattcagtag
  1010521 tatcattgct ttaatatttt ggttccaaag tatataaaaa attactccaa ctcaacatgg
  1010581 agaatttgtt attttacttt tagccagatt ttctggtaaa ataatatctt cgatataaat
  1010641 atatttgatc acaaaatata tcttttatat aacgtcgccc attgcggtgt ttttttattt
  1010701 ttggagtatc aatatgaatc taacaattaa cgctttaaca agaaattacc aaggtaaagg
  1010761 tgcgaaccgt cgtctacgtc gaaataataa aattcctgct attgtttatg gtactggcaa
  1010821 accacctagc aaaataacct tagatatttt tgaaattact cacttattaa aaaatgagga
  1010881 aacttacact tcagtactta acctaatagt taacaaaaac aaagaagcag taattattaa
  1010941 aaatttacaa cgccaccccg ctaaaaatag catcactcat attgacttct tacgtattaa
  1011001 cttaaaccaa tctattatca ctagtatccc tatacaattt aacggcgagg aagataataa
  1011061 ggccatgcgt ctaggtgcag ttcttaatca atttatgact gccattgaaa tttcttgctt
  1011121 accaacaaac ttacctcaca gtattaatgt agatatcagt catcttacaa taggtgaaca
  1011181 tattaacttg acagatatta atataccaaa aggtatagtt atcaccgcat taacacacgg
  1011241 tgatattgaa actcataacc aaagtattgc tataattcaa gagcctagaa agatggctga
  1011301 aattgaagaa aatatccttg ttaaagctga agatagtaaa aataaaatta ctaaagataa
  1011361 tgaaactaac aaagataaat caaatttata atttatccaa acatgacgat aaaactaatt
  1011421 gttggcttgg gcaacccggg caaaaactat aaataccatc gtcataatgt tggattttgg
  1011481 ttttgtgacg ctttagctaa actatacgct ggaaatttta aaaaaagaac taagttcttt
  1011541 ggtgaagtca cccagattaa tatatttaat cacaaaattc aattactcaa acctactaca
  1011601 tttatgaatt gttctggtca atcaattcaa agtattgcta atttttatca aattaatgct
  1011661 gatgaaatat taatcgtaca cgatgaacta aacatcaacc ctggcattgc caaaattaaa
  1011721 tcagggggta gtcatggtgg acataatggc ttaaaaaaca ctattaaaat cttagaaact
  1011781 aaagcatttt acaggctaag aattggtata ggtcatccag gtaacaaatt accaatagtt
  1011841 gattttgtac taaacacacc cagtaaggac gaattggaca aaatacaaaa cgctttgaac
  1011901 aattcgttac aagtaattga agatgtgatt aaaaataact tggataaagt cataaaaact
  1011961 ttacaaaaaa aagaaataat ctaagggggt gataaaatgg gatttaaatg tggcatagtt
  1012021 ggtctaccaa atgttggaaa gtcaacctta ttcaatgcat taactcaatc taatattgaa
  1012081 tctgtcaact accctttttg tacaattaaa ccaaatatcg gtattgtacc tattaatgat
  1012141 gaacgcttag ataaattagc aaaaattatt aaccctaaaa aaattatacc tgccataata
  1012201 gaatttgttg atattgctgg attagttaaa ggcgcttcaa aaggtgatgg actaggcaat
  1012261 caatttttaa ccaatatacg tgaaacagat gcaattatcc acgttattcg tgcttttgat
  1012321 aatgataata ttattcacgt atcaggaaaa gtttcaccac ttgatgatat tgaaattatt
  1012381 aataccgaac ttattctagc cgatttgaat gtagttgaaa aattgtataa aaaatccctc
  1012441 aaaaatacca aatctggtca aaaagatggt atcccccttc acaatatatt gacaaaaata
  1012501 ttatctgtac ttaacaatgg caatagtata cgtacgctct cgtttgataa agaagaatta
  1012561 aaattactaa aaggtcttca attacttacc attaaaccaa ttttatacgt tgcaaatgta
  1012621 agcgaagtag gctttttaaa taatccttat ttaaagataa tagaaaaatt atccaacaaa
  1012681 gaaaatacac aaattgtcac aatttgtgct aaaacagaag atgaaatttc agaattagac
  1012741 aaaaatgaaa aacaagagtt tctatctgaa atgggacaaa gtgaatcagg actagataga
  1012801 ttaattaaag caggatataa attattagga ttacaaacat attttactgc tggggctcaa
  1012861 gaagtaagag cttggacaat taacattggt gataaagctc cacaagctgc tagtaaaatt
  1012921 catagtgatc ttaaaaaagg ctttattcgc gcacaaacca tcgcattttc tgattttatt
  1012981 gaatttaagg gtgaaaaagg cgcaaaagag gctgggaatt tacgttcaga aggcaaagaa
  1013041 tatatcgttc aagacggtga tatcatacat tttctgtata atatataaac ttatttaata
  1013101 ctaaatataa acttatttaa tactaaacta atgaaatcta aaaaacaaac aaaactattg
  1013161 ttaattctag atggatgggg ttattctaaa acaaccaaaa ataatgctat tgcactagca
  1013221 aatacatcag tttgggatag attaaatcaa accttcccac attctttaat tcataccagt
  1013281 ggcaaagacg ttggcctacc tggaaaacaa atgggtaatt cagaagttgg gcatcttaat
  1013341 ctaggtgcag gacgtattgt aaaacaagac tttactcgaa tttataacga acttcaaaat
  1013401 ggtgatttct ttagaaatcc aattctaaga aactcgttag aatacgcaaa tgataacaat
  1013461 aaagctattc acattatggg gcttttatct gatggtggcg tacactcaca cgaagaacaa
  1013521 atccacgcca tgttagaaat gacatctaga caaggttgta aaaacgttta tttacatata
  1013581 tttacagacg gtagagattg cgcacaaaaa agtgcaaaaa aatacattaa aaaacttgaa
  1013641 agtaaaatga aagagcttaa tacgggagag attgttagtc tcattggtcg atatttttca
  1013701 atggatcgag acaatcgttg gtcacgtata cgttacgctt atgaacttat agcaaaaggt
  1013761 aaagcaaagt ttttagccaa atctgcttta aacgctatag aattagcata cgcacgtggc
  1013821 gagactgatg agtttatcca atcaacctca attaaagcac caacctcaat aaaaaaaggt
  1013881 gatgtgttaa ttcttatgaa ttaccgtgca gatcgtgcta ggcaaattac atgtgctttt
  1013941 actgatgaag attttcaagg gttttcacgt ggaacattcg tcccaacaca atttgtttgt
  1014001 ctaactgagt acaaaaaaga ctttaaccta ccagtagctt atccgtcttc taaactaaac
  1014061 aatgttctag gaaaatattt atcaaattta ggcatgactc aacttagaat tgcagaaact
  1014121 gaaaaatatg cacatgtaac cttttttctc aatggtggca tagaacaagc ttttaacggt
  1014181 gaagaacgtg tgttaattcc ttcacctgat gtagctactt atgacttaca acctgaaatg
  1014241 agcgcatttg aactcactga tgcattggtt gaaaatattg aaagccagaa atatgactta
  1014301 attatttgca attttgctaa cactgatatg gtaggacatt ctggcaaact agatgccact
  1014361 attaaagctg ttgaagccgt tgatacttgc ttagggatta tttacaaagc tatgtttgcc
  1014421 attggtggtg aaatgctaat cactgctgat catggcaatg cagaacaaat gattaaccct
  1014481 caaacaaatg aagtacatac agcacacacc aataatccag tacctttaat ttttgttagt
  1014541 aaccgaaagg cagatattat gaaaccaggg aaaggcgcat tgtcagacat tgcaccaaca
  1014601 ttattagcaa tgatggatat tgaaaaacca gatgaaatga ctggaaatag tttgttaaca
  1014661 tttaagtaaa ataacaagat taacctctca aggagactca tgaaacaagc taattttatt
  1014721 gccccttcaa ttctttcggc agacttttcc agactaggtg aagaagttga taatgtactt
  1014781 aaagatggtg ctgatatcat ccactttgac gtaatggaca atcactatgt accaaattta
  1014841 accatcggtc ctttggtatg tgaagcactt aaaaatcatg gcgttagtgc accaattgat
  1014901 atccacttga tggtaaaacc cgttgataac attatcccca atttcataaa agctggtgcg
  1014961 tcatatatta cttttcaccc agaagcatca gagcatattg atagaacatt aggtatgatt
  1015021 caagaaggag gttgtaaagc tggcctagta ttcaatcctg caacaccaat acacgtacta
  1015081 gaaaatgtta tgagcaagct agatataatt ttattgatgt ctgtcaatcc cggctttggt
  1015141 ggacagtcct ttattcctca tacattagac aaatgtcgtg aggtcagaaa actaattgat
  1015201 gcaagtggta gaaacattcg tttagagatt gatggcggta taaaaattaa caatattcat
  1015261 gaaatatcca aagctggtgc agatacattt gttgctggct ctgcaatctt taaaactgac
  1015321 aattacaaaa caaccataga tgcaatgcgc atgaagcttg ttgaagttta attaacttga
  1015381 agagttaacc taactttggt ataatacgtc gttagattaa atctatttat acctacaaat
  1015441 aacaatagat ttaaagttga acttagggtt atatgattct aagctcaaag gtaaagatac
  1015501 caaacttatt ttaatgtacc atataactcg acatatattt agtcaggagt cttgtaaaag
  1015561 aattgactag tagaagtttt aaaagaaggt gtcaataagc gctttactaa ctctaacctc
  1015621 cttggagaag atataatggc aaaaacgtca atgaaaaaaa tgctagaaac tggtgtacac
  1015681 tttggtcacc gtgctcgttt ctggcaccca aaaatgaagc gctttattta tggtactcgt
  1015741 aatggtattc atattatcaa tctagaaaaa acacttccca tgtttaatga tgtgcttaac
  1015801 tttataaaca aaactgtaaa agctggtaga tctatcttat ttgtaggtac aaaaagagca
  1015861 gcaagcaaca ttatcaaaca agaagctata cgttgtggca tgccatacgt caatcaccgt
  1015921 tggttaggcg gcatgatgac taactataaa accatcaaag cttctattaa acgactaaaa
  1015981 gatctcgaat ttttagcaga agagaacttt aatcaatttg gcaaaaaaga agcactcata
  1016041 atgaaacgtg aaatgaaaaa attagaacgt agcctaggcg gtattaaaga tttaggaagt
  1016101 attccagatg ttgtatttgt gattgatact ggaattgaaa agaatgcagt agcagaggct
  1016161 aaaaaactac acttacccat tattggcatt gtagatacca accataaccc tgaaggtatt
  1016221 gattatgtta tccctggcaa tgatgattct attagagcaa ttggttttta cgcaagagaa
  1016281 attgcaaaca ctattttaga aaccaaagct acttatagct caccaataaa taaaaaagtt
  1016341 tcagttaaaa aatcagaaac tcaaaaacca aaaattaaaa aagcacctgt tgaacaaata
  1016401 ctagtaaaaa aaagttacta acacacctat gaaaaaatac caatctaaaa agataaattt
  1016461 aacaaccctt aaataaaata aaaaaactaa tttaattgtt tctactgaaa taaagcaaaa
  1016521 tatagctatt aacagttcaa acaaatacta agactaaaca acacattata ccaatacatt
  1016581 gttatatctt aaaagataca acaaaaatag gaaattaatt atgaaaatta cagcctcttt
  1016641 agttaaaaag ttaagacaaa gaatgggagc aggtatgatg gattgtaaaa aagccttaaa
  1016701 tgcaaccaat ggtaatatag aaaaagctat tgatttaatg cgcactttaa atactaccaa
  1016761 atccgctaaa aaattagatc gtattacaat cgaaggctta gtcaaaatta acattagcgc
  1016821 taataaaaaa acagttacta ttttagaagt caactctgaa actgattttg ttaccaaaag
  1016881 tgatactttt attagctttg ttaatatgct aggagtgtta gcactgaaaa caacacctac
  1016941 taatattgaa gaatttttat ctcaaccact aagcaacgga gactcaatag aaaaagcacg
  1017001 tgaagaaatt attgcaaaag taggtgaaaa tattacgatc agacgtgtac aaacaatcaa
  1017061 aacgaataat ggtattattg gtacatataa gcatatggat cgtattgctg tagttacaat
  1017121 tttagaaaaa ggggatgaaa cacttgcaaa agacattgca atgcatattg ctgctaccaa
  1017181 cccagaatgt attactgaag cagaattatc atcagatctc ttagaaagag agaaagcaat
  1017241 ttttattgaa caaagcaaaa aatctggaaa accaaataat attattgaaa aaatgattat
  1017301 tggtcgtatg aaaaaatttg ttaacggggt aacactatat ggccaacctt ttataaaaaa
  1017361 ccatgacaca acaataggaa aacttatgca attaaataat acacaggtaa agttttttgt
  1017421 acgatttgaa gttggtgaag gtattgaaaa aaaagaaaaa aactttgttg atgaagttat
  1017481 ggcacaaatt taaaaatagc ttgtattcac attatttacc aaaatatttc tgtttatttc
  1017541 aaaaaaaata gtgcttacct gatcacaata ttattaacat aatcaacagg ttaacaatta
  1017601 acaattttta aataaatatt ctttatctta taatttaaag tatttaaaat aaaaatacaa
  1017661 actttaacaa aataaatttt tgtaaatatt atttagtaaa taacaaatca tagaacatct
  1017721 ttaatagata ataatctagt catattagta atactaatat tgccaattta tcagttattt
  1017781 ataaaatata atccattata cttagaaact cttttaatca acctatatct cctatattat
  1017841 taaataagtt atacttcaat ttatgtaaat gtaaaagacc accataaata gtggtcttta
  1017901 tttaatcctt aaatactaaa cttaatcaag aagcacaagt ccaacaagaa aaaataattt
  1017961 tacttagaaa tcacttgatc gcgactatca gcagttgcat tagctttagc atctgcatac
  1018021 cccttagcat atgcatcagc ttgtgcttta gcatatgcat cagcttgtcc cttagcatat
  1018081 gcatcagctt gtcctttaac gttagcatca gcaatacctt catattttcc atcaacactt
  1018141 gcattagaaa catttttagt tttattcttg ttgttataat gaaaacccca atcagaatca
  1018201 ttattcatat tattattatt cgaaaaagga ccccaattat tagcgccgtt aaaaggaccc
  1018261 caattagaac taccatcaaa aggaccccaa ttattagcgc cgttaaaagg acctatattt
  1018321 gaaccgctat tcattggacc ccaattagaa cccccatcca atgggcccca attatttgaa
  1018381 ccgctaccat agccgtagcc gttattattt gaactattat taaagaaacc agctgatact
  1018441 gatgtaacag ctaccaaagt agaaataaca attatctttt tcatattaat ctccaaattt
  1018501 aaaagtatta actctcttat tcttaagaga gttttaagta tcaaacctta taagtcttga
  1018561 tgaaaatatt atacgataaa tatattataa gtcaataata ttctaatata tttttttaga
  1018621 aaacgactag aaatactaaa ttaatataga gttaacaaaa taatttagta ttattaaact
  1018681 agttttgata gaacaaactc ttagttacta acattaagta ccataaagaa gttaggtatc
  1018741 ataatcttaa aacatcaaca cacaaccata ccttatagtc tttaacattc aactaacaat
  1018801 aattttatta ctctataaga gagtaatatt ttgaactaaa aataagatta taacaaagac
  1018861 taatagtctc aaatttcaat aaccaatatt aatactttta acgataatga aattctcttc
  1018921 atcaacaaaa atataattaa tcacattttc cacattaatt acaacatttt ccttaatcgg
  1018981 ttaacttaat gttttctaag aactaatccc taaaaatatt cttaaataac ttttaacaac
  1019041 acaaacaact catacgatta tctaaaattt taactctttg ttctaacatc tttctgaatt
  1019101 aatgatggct cttaacaata aataactaaa tctctacctt atggctattc aataataata
  1019161 agacaatcat cttattatta ttgaatctca atctttaagg tagagattgc tgcaggaaat
  1019221 aacatataac ccaaatcatt ataagttgta ttcattgatt cgaaaaaatt ttcctgatat
  1019281 tgattaatgt tatgattcat aataaaatta gattgtgaaa ttttattttt tttaaaagta
  1019341 aaagaaaaat cggttaacat caaccaatta ctaggcttaa ccctattctt aattcgaaaa
  1019401 tttatactat ttaacccaat attttggttt cttacaatat tataataatt cacaaagctt
  1019461 aaagagttac aataaggata gtttgcttga ttattataat ttgacattcc ataattacca
  1019521 ctccaaaatg caaatgattc attaaatgtt attaatagaa aaaataataa ccagttaaat
  1019581 ttttgcataa aaatacctaa tcaatcatca tctacttatg taatcaataa atatccctgt
  1019641 cgaaacaccc ccttacatga gttttacaaa aatgctaata ataattttaa aatctaaaaa
  1019701 ttgattaaag caaactatcc ttattgtaac tcttctttag ccgaaaacta ttaaacttgg
  1019761 atattaattt aataagagta ggcataaata ttacacataa caattaataa caaataatac
  1019821 tattcattat ttttacccac actattgtag tcaattcaat caatcactta attataagat
  1019881 attcaaaaaa atctaaccaa attatcaaac ttaacaattt taatatacag tcttttataa
  1019941 acttaataag taatatattt tattatccaa tatttatact attgatttta atatcaatag
  1020001 atattaaaat caatagatag aattaatact tctaacactt ctggtgtaat cattcaaatt
  1020061 gacactatca aataaataaa ctaaatacta gttattacac aacccataat ttaaacaatg
  1020121 ataaatcgtt attaaacgat atatcataaa ttaaaaacag ttttaaatct tataaatact
  1020181 aaatataaaa ttattaatac ttttttcatc ttaacattaa aatttactta cactattttt
  1020241 acaatacatt attacataaa aacaaatata ttaaaccatg gtgccgatgg ccggactcga
  1020301 accggcacaa gcatagctta ctaccccctc aaggtagcac gtctaccaat tccgccacac
  1020361 cggccatatg agttagtaat attaataatc tggaatatca ataacatcta acttatttaa
  1020421 aataggagta accgtagcaa taggaacatc aggtaccact agctttcctg tcgttacttg
  1020481 ttccataata cttattggct tattaccaat actaccatca tgagtcgcta aataagctaa
  1020541 cgtcaaacta gttaaaaaaa agcccaaaga taaaccagta attaacttat aaagaaatga
  1020601 atttgcacct cttacaccaa aaaccgaacc agaaacacca gcaccaaaag ctgcacctgc
  1020661 atcagcacct ttaccatgtt gcattaaaat taaaacaatt aaacttagtg ctaaaaacat
  1020721 atgaacaatc aaaataaatt gaaaagacat cattaactag ccttacaaat ttgtaagaaa
  1020781 tcttgcgctt taagtgaagc ccccccaatt aatcccccgt caatatcttt acaattcatt
  1020841 aattcagctg catttctagg attcatacta ccgccataaa gaatcgaagt aatttgtgaa
  1020901 acattatcat catatttagc aagcattgaa cgaataaaag catgtgtatc ttgtgcttgc
  1020961 tgaggtgttg cagtaatacc tgtaccaatt gcccaaactg gttcataagc cacaataata
  1021021 tctttaaacg catcaatacc aaccaaatca attaccgctt gaatttgttc tgaaaccact
  1021081 tcctgagtct tgccagaatc tctatcttct aataattctc caatacacaa aagtggagtt
  1021141 aagttattat tcaatgcaac ttgaactttt tgtgcaacaa tctcattatt ttcaaaataa
  1021201 agacttctgc gttctgagtg acctacaata acatatcgag caccaaaatc tttaatcata
  1021261 tcaacactaa cttcacctgt aaaagcacct gatttattaa tattcaaatc ttgtgcgcct
  1021321 aaatttagtt gtgaacaacc aactaatgct tcaacctgtg ccatataagg aaaaggtaca
  1021381 caaataatta ccttagattt aacatctacc ataccagata aaatatccat tactaatatg
  1021441 ttagttgctt ctttagaagc attcattttc cagttacctg ctatgattac ttgacgcata
  1021501 ataattatct tattaaaaaa agaaataatg ttacgccatt taattataaa aatcaaatct
  1021561 ctaaaaaatt aatgtgaaga tttagagcca aaatacaaag ccaatgaaac cattaaaata
  1021621 cctaaagaaa aataaatcaa atctaatgat gaattaaatg acattgacaa agacacttca
  1021681 aaaaaagtaa ccactaaaat cataagtatt actttagcaa gtttagactt taaatcatct
  1021741 aacgaattaa tcaccaatac tttagatgat tgatcactct ctttagcctc atcaatatca
  1021801 ctaataaaaa gttcatataa acctaatgaa aaaatcaata aaatagttgc taacaaaaac
  1021861 ccatcaatcg aacccactgt atgtgcaact aattcaatct ttaatacctt tctaacctct
  1021921 gatgtagcta ttatataatc aaaagtatga actaataaag caaatacatc aactgcagta
  1021981 atcacaaaaa gtaataatga caataataat gaagaaataa cagctactaa aaccatataa
  1022041 cgagaacccc acaataattt ttcaaaatac ttttctaaac cattcattga ataaccccac
  1022101 acacataata ctaatacttt agtatatcat tacttaattt taattcaaat tttt
//
