LOCUS       NC_022608               9614 bp    DNA     circular CON 29-OCT-2013
DEFINITION  Carnobacterium sp. WN1359 plasmid pWNCR9, complete sequence.
ACCESSION   NC_022608
VERSION     NC_022608.1  GI:554651112
DBLINK      BioProject: PRJNA225603
KEYWORDS    RefSeq.
SOURCE      Carnobacterium sp. WN1359
  ORGANISM  Carnobacterium sp. WN1359
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Carnobacteriaceae;
            Carnobacterium.
REFERENCE   1  (bases 1 to 9614)
  AUTHORS   Nicholson,W.L., Leonard,M.T., Panayotova,N., Farmerie,W.G. and
            Triplett,E.W.
  TITLE     Complete genome sequence of Carnobacterium gilichinskyi strain
            WN1359
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9614)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2013) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 9614)
  AUTHORS   Nicholson,W.L., Leonard,M.T., Panayotova,N., Farmerie,W.G. and
            Triplett,E.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2013) Microbiology & Cell Science, University of
            Florida, 1355 Museum Road, Gainesville, Florida 32611, United
            States
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to CP006817.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Assembly-Data-START##
            Assembly Method       :: Celera Assembler (CA) v. 7.0
            Coverage              :: 103x
            Sequencing Technology :: Pacific Biosciences
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 10/21/2013 14:35:35
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.2 (rev. 415568)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 2,426
            CDS                          :: 2,275
            Pseudo Genes                 :: 50
            rRNAs                        :: 25 ( 5S, 16S, 23S )
            tRNAs                        :: 75
            ncRNA                        :: 1
            Frameshifted Genes           :: 27
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9614
                     /organism="Carnobacterium sp. WN1359"
                     /mol_type="genomic DNA"
                     /strain="WN1359"
                     /isolation_source="Siberian permafrost"
                     /culture_collection="DSMZ:DSM 27470"
                     /db_xref="taxon:1266845"
                     /plasmid="pWNCR9"
     gene            586..849
                     /locus_tag="Q783_12135"
                     /db_xref="GeneID:17373176"
     CDS             586..849
                     /locus_tag="Q783_12135"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="REF_PRJNA222287:Q783_12135"
                     /protein_id="YP_008719560.1"
                     /db_xref="GI:554651120"
                     /db_xref="GeneID:17373176"
                     /translation="MARIDTKNLSDSLKYFLEKEAAEKNLSLNKLTKEIFEDYTKDKL
                     SFESEKRFNDSINQAIKILNKNTETVDTYIKSNAKLIEILTEE"
     gene            898..1275
                     /locus_tag="Q783_12140"
                     /db_xref="GeneID:17373163"
     CDS             898..1275
                     /locus_tag="Q783_12140"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="REF_PRJNA222287:Q783_12140"
                     /protein_id="YP_008719561.1"
                     /db_xref="GI:554651121"
                     /db_xref="GeneID:17373163"
                     /translation="MTKEPSKNRSIRLTDTVMNELNKIVEEDEIRSLNNLMELLIVAY
                     KENKTTAFKNQKKSSDSIKKDINLVKKELATLLYLNETMADFLSITTINEIDTKDSLV
                     NQSREKVKRDIERNQVKKASNLY"
     gene            2537..3019
                     /locus_tag="Q783_12145"
                     /db_xref="GeneID:17373164"
     CDS             2537..3019
                     /locus_tag="Q783_12145"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="REF_PRJNA222287:Q783_12145"
                     /protein_id="YP_008719562.1"
                     /db_xref="GI:554651122"
                     /db_xref="GeneID:17373164"
                     /translation="MTDKTVKEVAEMLGVTKQTVQYHLKSLPTNYTTKSDKNIIYIKP
                     LGQKALSDKIDKRKQFSVDKETVKTDKEPTKETVGNNKEMAHYKEQIKEKDQQIAQLL
                     ESQKQLQKLIENQQVLTLQANQKIEKLEINLNDVENEIKLDPESKKRKWTDIFKSRNR
                     "
     misc_feature    <2549..>2617
                     /locus_tag="Q783_12145"
                     /note="Helix-turn-helix domain; Region: HTH_20; pfam12840"
                     /db_xref="CDD:257340"
     misc_feature    order(2549..2551,2558..2560)
                     /locus_tag="Q783_12145"
                     /note="putative Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238042"
     gene            3050..3406
                     /locus_tag="Q783_12150"
                     /db_xref="GeneID:17373165"
     CDS             3050..3406
                     /locus_tag="Q783_12150"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:YP_003429174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="REF_PRJNA222287:Q783_12150"
                     /protein_id="YP_008719563.1"
                     /db_xref="GI:554651113"
                     /db_xref="GeneID:17373165"
                     /translation="MKNTFNKLFERIASIMFALTLVFDYFPEIGISYKVSALVMILFI
                     VLAVITQDHLHYSIKSLKLEFLTVTAIMLLLLILSLIGGESQNGLNLDNPIIWFLYFG
                     SLFTIIVKYKRKKTYM"
     gene            3760..4221
                     /locus_tag="Q783_12155"
                     /db_xref="GeneID:17373166"
     CDS             3760..4221
                     /locus_tag="Q783_12155"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="REF_PRJNA222287:Q783_12155"
                     /protein_id="YP_008719564.1"
                     /db_xref="GI:554651123"
                     /db_xref="GeneID:17373166"
                     /translation="MSSYIYLSSDTFLPEGAIGDKGLTVFQTTFYPSLNSMESFFFEN
                     NYDTDEQKVLSFSKHFSSEKYQVASIDLNLPENDGKKISKRNKKALEELFGYIKNHFD
                     NSNASYVEILFCLNGFENDPLQHNYSINYNELSANDLLYEELKFLTIKKQD"
     gene            complement(4238..5098)
                     /locus_tag="Q783_12160"
                     /db_xref="GeneID:17373167"
     CDS             complement(4238..5098)
                     /locus_tag="Q783_12160"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="REF_PRJNA222287:Q783_12160"
                     /protein_id="YP_008719565.1"
                     /db_xref="GI:554651124"
                     /db_xref="GeneID:17373167"
                     /translation="MKKIINKGIIIFSSVLLLAPTLQTHAYAETVSPEEAFSEELAEE
                     NLELVDSELAIDESGEELYILTVETETGDSIDLKLNMDSNDITVEALSDVTGEIENYS
                     ISLPEDAEITGEDTYTEELEDITVENEITGDVYEYEDLEGEFSGALAIPSAIPIVWSA
                     LVSLYNSGLAIVAAGATFIVAGHAISKIMNNKNKKNHYLATIVKGKLYIGKGVSDSAA
                     VTQLRSGKSTWSISSNQAKNIASKLAKGSPIKEVDKDTKGNPKKGYYWHWHSSTRNPK
                     GHHAFYGYPV"
     gene            complement(5161..5820)
                     /locus_tag="Q783_12165"
                     /db_xref="GeneID:17373168"
     CDS             complement(5161..5820)
                     /locus_tag="Q783_12165"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="REF_PRJNA222287:Q783_12165"
                     /protein_id="YP_008719566.1"
                     /db_xref="GI:554651125"
                     /db_xref="GeneID:17373168"
                     /translation="MRKKFLLLFLLICFTLINSSDSIKQESNSIELVIIDSGISKKME
                     YSLPNNWSIKHYNSKENKNNHADLVLQQILNNVEYQENVNVIIHDVVVSNSNNISVDS
                     LYNTLNIAKKFNADIINLSLGISINSDDIKSVIDDISKDNTIIVAAAGNKFGMSAQYP
                     ARYKTVISVGSLDLKGNVSDFSAMKYVDEYRLGEYDSYSGTSFSAPIVTAEIINNFFE
                     H"
     misc_feature    complement(5194..>5493)
                     /locus_tag="Q783_12165"
                     /note="Peptidase domain in the S8 and S53 families;
                     Region: Peptidases_S8_S53; cl10459"
                     /db_xref="CDD:263972"
     misc_feature    complement(order(5215..5217,5455..5457))
                     /locus_tag="Q783_12165"
                     /note="active site"
                     /db_xref="CDD:173787"
     misc_feature    complement(5215..5217)
                     /locus_tag="Q783_12165"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:173787"
     gene            6210..6695
                     /locus_tag="Q783_12170"
                     /db_xref="GeneID:17373169"
     CDS             6210..6695
                     /locus_tag="Q783_12170"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:ZP_02185672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein FlaR"
                     /protein_id="REF_PRJNA222287:Q783_12170"
                     /protein_id="YP_008719567.1"
                     /db_xref="GI:554651114"
                     /db_xref="GeneID:17373169"
                     /translation="MNYKGKIHIIGSVGSGKTTLAKKISEKLAIPYYEIDNIIFERHP
                     TGDIRRSDEEIITILENIINTETWILEGTCTKEWIVSSFAKADQIILLDIPYLTRLKR
                     IIFRYVKQVLKVESANYKPTITMFKHMIKWNHKFNKVNKIDFYRLTKKYREKIIVYTH
                     N"
     misc_feature    6225..6689
                     /locus_tag="Q783_12170"
                     /note="AAA domain; Region: AAA_17; cl19128"
                     /db_xref="CDD:267481"
     gene            6836..7387
                     /locus_tag="Q783_12175"
                     /db_xref="GeneID:17373170"
     CDS             6836..7387
                     /locus_tag="Q783_12175"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:YP_004373744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="REF_PRJNA222287:Q783_12175"
                     /protein_id="YP_008719568.1"
                     /db_xref="GI:554651115"
                     /db_xref="GeneID:17373170"
                     /translation="MSYNVQPLRTQQEINDFLFCLRRNKNADRDVFLFLIGINSGLRM
                     SDIVKLKKQDLISSKNPRIVEKKTGKTRILYLSSLQDLILEYTKDLAPEDYLFPSTKG
                     GHVEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     misc_feature    6842..7378
                     /locus_tag="Q783_12175"
                     /note="DNA breaking-rejoining enzymes, C-terminal
                     catalytic domain. The DNA breaking-rejoining enzyme
                     superfamily includes type IB topoisomerases and tyrosine
                     recombinases that share the same fold in their catalytic
                     domain containing six conserved active site...; Region:
                     DNA_BRE_C; cl00213"
                     /db_xref="CDD:260266"
     misc_feature    order(6962..6964,7220..7222,7229..7231,7298..7300,
                     7325..7327)
                     /locus_tag="Q783_12175"
                     /note="active site"
                     /db_xref="CDD:238231"
     misc_feature    order(6962..6967,7034..7036,7214..7222,7325..7327)
                     /locus_tag="Q783_12175"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238231"
     misc_feature    order(6962..6964,7034..7036,7220..7222,7229..7231,
                     7298..7300,7325..7327)
                     /locus_tag="Q783_12175"
                     /note="Int/Topo IB signature motif; other site"
                     /db_xref="CDD:238231"
     gene            7460..7681
                     /locus_tag="Q783_12180"
                     /db_xref="GeneID:17373171"
     CDS             7460..7681
                     /locus_tag="Q783_12180"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="REF_PRJNA222287:Q783_12180"
                     /protein_id="YP_008719569.1"
                     /db_xref="GI:554651126"
                     /db_xref="GeneID:17373171"
                     /translation="MIHSAAKRKIRTATFVVFVLFTLAFLFSTGEDSSIFSMFIMSIY
                     FGLLVSTIFFILISIITYIITLVSGWLNN"
     gene            7889..8218
                     /locus_tag="Q783_12185"
                     /db_xref="GeneID:17373172"
     CDS             7889..8218
                     /locus_tag="Q783_12185"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:ZP_02185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="REF_PRJNA222287:Q783_12185"
                     /protein_id="YP_008719570.1"
                     /db_xref="GI:554651116"
                     /db_xref="GeneID:17373172"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYNKQDILKEFKNRKSELTYAFRSIAEDTAVHSKPMTKEE
                     LAAEIGL"
     misc_feature    7889..>8032
                     /locus_tag="Q783_12185"
                     /note="Antidote-toxin recognition MazE; Region:
                     Antitoxin-MazE; cl00877"
                     /db_xref="CDD:260674"
     gene            8208..8495
                     /locus_tag="Q783_12190"
                     /db_xref="GeneID:17373173"
     CDS             8208..8495
                     /locus_tag="Q783_12190"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:ZP_09441584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin RelE"
                     /protein_id="REF_PRJNA222287:Q783_12190"
                     /protein_id="YP_008719571.1"
                     /db_xref="GI:554651117"
                     /db_xref="GeneID:17373173"
                     /translation="MAYEILPSKHVVKYLKKLKEKPLKEQFLTLIYDEIALHPHSGEQ
                     KTGDLSGIWAMGFKYAGTTYRVAYEIKENKVIPLLLCGTHENFYEQLKKIK"
     gene            8651..8980
                     /locus_tag="Q783_12195"
                     /db_xref="GeneID:17373174"
     CDS             8651..8980
                     /locus_tag="Q783_12195"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:YP_003843828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="REF_PRJNA222287:Q783_12195"
                     /protein_id="YP_008719572.1"
                     /db_xref="GI:554651118"
                     /db_xref="GeneID:17373174"
                     /translation="MQNKEYYELIERDNTNPKDNERRALFTILSENEELYSKIDSLYD
                     FENHWINDDCFEKIDFSNGTRKLVQLAFNLYNNNPSPTPLEIFSSLDSDNYDLAMKAI
                     NIRFNKI"
     gene            complement(9035..9253)
                     /locus_tag="Q783_12200"
                     /db_xref="GeneID:17373175"
     CDS             complement(9035..9253)
                     /locus_tag="Q783_12200"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:ZP_02186043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="REF_PRJNA222287:Q783_12200"
                     /protein_id="YP_008719573.1"
                     /db_xref="GI:554651119"
                     /db_xref="GeneID:17373175"
                     /translation="MIGILENYQANYKAIIHSEKLSNCRKNALLRNLLSEIDYIFFGA
                     CDKEQSIIDQQEEAKNLHTYIQKNLIIC"
CONTIG      join(CP006817.1:1..9614)
ORIGIN      
        1 tggattggtt gatcatttta aaaaattgaa gctgctttta gaaatgtttg ttgcagaatg
       61 tttctttttt ttgctgataa aaaagaaaaa taaagtacag atgaagaaca aatagttatt
      121 ttttcttcat gtaaacaagt tcagttttta ttttttatta ataaaaaagc tggtaaaatt
      181 tctttcaaaa agagtggaaa acgcactact tttgcagcac atatgtgtta tacttgcgtt
      241 acgtaatgca acacattcgc aacacctcca taggacaagc gcattacaca attttctaga
      301 aacgttgata ggtcggggtt aaaggtgctt ttggaaaaag tggtaaaaac agcctgttag
      361 gcgccagatt tttttagtga gattcatcag gcacagcctg atacgtcaac gttttggagc
      421 aacgcgaaaa agcgagtgac gccagaatct ctttatgctc tttctaagaa acagtaaaaa
      481 tacacaacta accccagtgt aaaaaacaac tatttctgaa ctcgcacctt tttgatcgtt
      541 ttgactaatg aataacagct aaaaaaattg aattaggagg atattatggc tagaattgat
      601 acgaaaaacc tatcagattc cttaaaatat tttttggaaa aggaagcagc tgaaaaaaat
      661 ctatcgctta ataaactaac caaggaaata tttgaggatt atacaaaaga taaacttagt
      721 tttgaaagtg aaaaacgatt taatgattca ataaatcaag caataaaaat cttgaataag
      781 aacactgaaa ctgtagacac ctatattaaa agtaatgcta aactaatcga aattttaaca
      841 gaagaataaa aaataattag tcgttaaatt aaaaaaatac aaaggtaggt aaatgatatg
      901 acaaaagaac cgtcaaaaaa tagatccatt cgattaaccg atacagtcat gaatgaacta
      961 aataaaattg tggaagaaga tgagatccgt tcattaaata atttaatgga gttattaatt
     1021 gtggcctata aagaaaacaa aacgactgct tttaaaaatc aaaaaaagag ttcggatagt
     1081 atcaaaaaag atattaattt agtgaaaaaa gaattagcta ctttacttta tttaaatgaa
     1141 actatggctg actttctttc tattacgaca attaatgaaa tagatactaa agatagttta
     1201 gtaaatcaat cgagagaaaa agtaaaaaga gatattgaaa gaaaccaagt aaaaaaagct
     1261 tctaatctct attaaaagta aaaataattt cagcaaattt ttttgaattt gaaaaagaat
     1321 ttgttgaact gaactaaaaa ttaaaatgga taggctttaa aattcaaaaa aatgcgattt
     1381 aagaaacgtt aaacctctcg aagggaatta gccgtttgtt ttattaaaag tcgtcttagg
     1441 tatcaaaaaa agccgctgtt tagggtggct tttgaactgg atcgattaat tttaaaaaga
     1501 ataataaact ggaaaatacc ggtaatcagt caaaaaaggg caatttaact agtgataatt
     1561 tatttttatg taaagttgct atttagaatt gacagcgtta tactgaaaac aacttaataa
     1621 cacgtacata aaaagataca aaaaaagagt catcaggaat tggaagttcc cgataactca
     1681 agacaacgta agtgacacct tacgaagtcc attttttgat agtatatact aaaaaagaaa
     1741 cgaaacaaag cttcgttcac ttattagtat ataagaatca gaaaaaaagt caacgtttga
     1801 ggacgattga cgaggcttct taggcaggct tcgttgatcg tctttttgcg tacaaaaata
     1861 cagaggacaa actgtatgcg tgacagcaat gaaagggaca ggttaagcat tcgccgcttc
     1921 tataaaggaa tgctaggaac atctaaatag ggtcactgta tcccctgttg ttctgaatgg
     1981 tgactgcgac cgatttaacg gcaggggtgg taatcttagg ctgaaagcct ggtagcctaa
     2041 aacaaagctc ttagggaaga ttttaagagg gttttaggcg tgttgagaca acaataccaa
     2101 ctgatacagt atgtgatagt ggctccgctt cgtctcctga cgtcaaaaga gaaataccta
     2161 atcgacatag ttgtactcta gcaagctgat agtaatctaa aattattttc agtgagacta
     2221 gggtacaact atgctcaaca ccacaaacat cagccctctg tcagcagtcc gagtgccttt
     2281 tgtcaacgat taaaccgaca tttagacgaa aaaacttagt tggattgctt aatcagaagg
     2341 attaggaaaa cttgctagaa attgcgaagg tggagcgcag cggttaccga gtgatttcta
     2401 gcaaccaatt ggctttagcc aatcaaaaaa taaattgctt aactttgctt acaataagaa
     2461 cgtttataaa tttatgtctt tacttgaata ggtagtttaa aatagggtac aaaatagcat
     2521 atatggaggt gtagttttga cagataaaac ggtaaaagag gtagcagaaa tgttaggtgt
     2581 aaccaagcaa acggtgcaat atcacctaaa gtctttgccg acaaactata cgacaaagag
     2641 cgacaaaaac atcatataca taaaaccctt ggggcaaaaa gctttatcag ataaaatcga
     2701 caaaagaaaa cagttctctg tcgacaaaga aacagttaaa accgacaaag aaccgacaaa
     2761 agaaacagta ggaaacaaca aagaaatggc acattataaa gaacaaataa aagaaaaaga
     2821 tcagcaaatt gctcaactgt tagaatcaca aaaacagttg caaaaattaa ttgaaaatca
     2881 gcaggtttta accttacaag cgaatcaaaa aatagaaaaa ttagaaataa acttgaatga
     2941 cgttgaaaat gaaataaagt tggatcctga aagtaaaaaa agaaaatgga ctgatatttt
     3001 taaatcaaga aatagataga acttttagta taatcaatgg aggtgttgta tgaagaatac
     3061 ttttaataaa ttatttgaaa ggatagcaag tataatgttc gctctcacat tagtatttga
     3121 ttattttcct gaaataggaa ttagctataa agtaagtgct ttggtcatga ttttatttat
     3181 agtattagca gttatcacac aagatcattt acactattct attaaatcac tcaaattaga
     3241 atttttaaca gtaactgcaa taatgttatt attactaata ttaagcctaa ttggtggaga
     3301 atctcaaaat ggtcttaact tagataatcc aatcatttgg tttttgtatt tcgggtcatt
     3361 atttacgata attgtaaaat ataaaaggaa aaaaacttat atgtaataca tgaaattgct
     3421 taaattaatg tatttaaaat cttgttttac taaggttatt ttcatcatta tatctaatac
     3481 aattagtttc tagttatact agtaaaaaaa gagctgactt atgaaatcgt acaaagatca
     3541 atagaattca attggcttat attgttaagt gaaataagga ggttttttag tggggtatag
     3601 tttgttcatt atttttttgc ttggcattgt tattatattt actaaaaaaa ataaacgata
     3661 agtttgaaat gaattatctt gtatttttca ttaaaataaa gtactttttg agtagagagt
     3721 gaaatactaa cttatatttt tatgaaaaag gggggttaga tgtcttcata tatatactta
     3781 tccagcgata catttttacc agagggggct attggagata aaggtttaac agtttttcaa
     3841 actacatttt atccttcatt aaattctatg gaatcttttt tctttgaaaa caactatgat
     3901 acagatgaac aaaaggtttt aagctttagc aaacattttt cttctgaaaa gtatcaagta
     3961 gcttccatag atttaaattt acctgagaac gatggaaaaa aaataagtaa aagaaataaa
     4021 aaagctctag aggagctttt tggatatata aaaaatcatt ttgacaatag taatgccagt
     4081 tatgttgaaa tattattttg tttaaatggt tttgaaaatg accctttaca acataattat
     4141 tctatcaact ataatgaatt atctgcaaat gatttattat atgaagaatt aaaattttta
     4201 acaataaaaa aacaggacta gtcctgtttt tttattgtta aactggatat ccataaaaag
     4261 catgatgccc ttttggattt cttgttgaag aatgccaatg ccaatagtat ccctttttag
     4321 gatttccttt tgtatcttta tcaacttcct taatcggact tcctttagct agttttgaag
     4381 ctatattttt tgcttgatta cttgaaatag accacgtact tttaccagat cgtaattgcg
     4441 ttactgctgc tgaatcggac acacctttac caatataaag ttttcctttt acaattgttg
     4501 ctaaataatg atttttttta tttttattat tcattatttt tgagatggca tgaccagcta
     4561 caatgaaagt ggcaccagct gcaactattg ctaaaccaga gttatataag gaaactaaag
     4621 ctgaccatac aattggaata gcactaggaa tagctagagc gcctgaaaat tctccttcta
     4681 ggtcctcata ttcatataca tctccagtta tttcattttc tacagtaata tcttctaact
     4741 cttctgtata agtatcttct cctgttattt ctgcatcttc tggtagagaa atactataat
     4801 tttcaatttc tccagtaaca tctgataaag cttcaacagt aatatcatta ctatccatat
     4861 ttaattttaa atctatactg tctcctgttt cagtttccac agtaagtatg tataattctt
     4921 ctcctgattc gtcaatagct agttcggaat caactaattc taagttttct tcagctaatt
     4981 cttcactgaa tgcttcttca ggacttactg tttcagcgta agcatgagtc tgcagagtag
     5041 gtgctaacag taatactgac gaaaaaatga taattccttt attaataatt tttttcatag
     5101 ttaaataacc ctcctttttt aataagctaa atatatgtta ttttcagtaa taaatctata
     5161 ctaatgttcg aaaaaattat ttataatttc agcggtaaca attggagctg aaaaagaagt
     5221 gccagaatat gagtcatatt cccccaatct atattcgtca acatatttca tagcagaaaa
     5281 atcactgaca ttacctttta agtctagact accgacagat ataacagttt tatatctagc
     5341 gggatattgt gcagacattc caaacttgtt tccagctgca gcaacgataa ttgtattatc
     5401 tttactaata tcgtcaataa cagattttat atcatcgctg ttgatactaa tgcccaaact
     5461 tagattgata atatcagcat taaatttttt tgcaatattt agagtattgt ataaggaatc
     5521 aacagatata ttatttgaat tagatacaac aacatcatgg attattacat ttacattttc
     5581 ttggtattca acattattta aaatttgttg taacactaaa tctgcatgat tgtttttatt
     5641 ttctttagaa ttataatgtt ttatactcca attatttggt aatgaatatt ccattttttt
     5701 actaattcca gagtcaataa taactaattc aatcgaatta ctttcttgtt taatagagtc
     5761 acttgaattt attaatgtaa aacatattaa taaaaataac agtaaaaatt ttttcctcat
     5821 tttccctcct attccctcct aaaataatat attattttat ttcctttttt cgtagttata
     5881 taatatataa tataacagca ttttatggat atttaaattt agttattttt tatgtagaaa
     5941 aaggaaccta attcctacga ataattataa gatacatgaa attacataaa aatgtgtatc
     6001 gagaacctta ttaaaacaag gttctttttt ttattatata gttcattttt gttgaattgt
     6061 ttattaaata aaaaacttct taatgatgaa acgagcagtt ataaatattt taatatacct
     6121 aaagaaatca atagatttat aatatagtta aagagctaat acataaatca aattatataa
     6181 aaaaaattag taaataaagg agctgcagga tgaattataa agggaaaata cacataatag
     6241 gatctgtagg tagtggaaaa acgacattag caaaaaaaat atcagaaaaa ttagccattc
     6301 catactacga aattgacaat attatttttg aaagacatcc aacaggagac attagacgat
     6361 cagatgaaga aataattact attttagaaa atataattaa tactgagaca tggattttag
     6421 aaggaacgtg tactaaagaa tggatcgtta gcagttttgc taaagcagat cagattattc
     6481 ttttagatat tccttattta actagattaa agcgaattat atttagatat gtaaaacaag
     6541 tcctaaaagt agaatctgca aattataaac cgactataac aatgtttaaa catatgatta
     6601 aatggaacca taagtttaat aaagttaata aaattgattt ctatagatta acaaaaaaat
     6661 atagagaaaa aataattgtt tatactcata actgaaatac atgaaattgt ataaaaacgt
     6721 gtatcgcgaa tcctatacct atagggttct ttttttataa agtcctcaaa tacatgatta
     6781 tatggtataa taaacaaaat catgtatcac ttttgtgaga ggagagggct tttaaatgag
     6841 ttacaacgtc caaccattac gcactcaaca agaaataaac gactttttat tctgtttaag
     6901 gcgcaataaa aacgcagatc gggatgtttt tctgtttttg atcggcatta atagcggttt
     6961 gcgcatgtcg gatatcgtca aattaaagaa acaagaccta atttcctcaa aaaatccccg
     7021 aatcgtcgag aaaaaaacag ggaaaacccg tattttgtat ttgagtagtc tacaggactt
     7081 gattttagag tacacgaaag acttagcacc agaggattat ttgtttccga gcaccaaagg
     7141 tggccatgtg gaagtcaata cggtctatca gatgtttcaa aaggtcgcta agctgttagg
     7201 aagagacgat attggcacgc acacgctacg taagacgttc ggctaccact attacaagaa
     7261 aaccaaagac gtggccacac tgatggaaat attcggtcat agcagcgaaa aaattacgaa
     7321 acgctatatt gggatcaatg aagatgaaat tagcgaaaca ttattaaatt ttagattagg
     7381 tttttagtat aatgtaaaag tattcgctta ctagtcttac ttttcagttg tagttcttaa
     7441 gataggaggg ctttacagaa tgatacattc tgctgctaaa cgtaaaatac gaacggctac
     7501 ttttgtagtt tttgtattat ttactcttgc atttcttttt agtactggtg aggattctag
     7561 tattttttct atgttcatta tgtctatata ctttggatta cttgtttcta caattttctt
     7621 catattaata agcatcatca catatataat tactttagtt agtggttggt taaataatta
     7681 aaaaaaattt gtactaattt attatctata ttagtttcta gtttatatga taattactta
     7741 cttgcttaac ataaaaccca attaaaccaa gtaaaactcc tttggaaatt attctgaagg
     7801 agttttatta ttttgtattt aggctaaaaa tagcgtacaa tgtaattact aagtaattac
     7861 acgatattta aataatggag gaaatcatat gattacaaaa acaagaaaac aaggaaattc
     7921 tattatgtta actgtcccta aagaattcga tgttcccaat ggtgttgaag tagaagctaa
     7981 gcttgtagag aatggtatcc tttatgagtt tgtagagcct aaaaaagagt tttttgattt
     8041 tagtgaagat attttagctg atattctttc agaaggttat aacaaacaag atatattaaa
     8101 agaatttaaa aatagaaaaa gtgagttaac ttatgcattt agatctattg ctgaagatac
     8161 tgctgtacat tctaaaccga tgacaaaaga ggagttggca gcagaaattg gcttatgaga
     8221 ttctaccttc taaacacgta gtaaagtatc taaaaaaatt aaaagagaaa ccgttaaaag
     8281 aacaattttt aacgctaatt tatgatgaga tagcccttca tcctcattcg ggagaacaaa
     8341 aaacgggtga tctatcagga atttgggcta tgggatttaa gtatgcaggc acgacttatc
     8401 gagttgccta tgaaattaaa gagaataaag tgatacctct attgctatgt ggaacgcatg
     8461 aaaattttta tgagcaatta aaaaagatta aataagaacc taatcttttt ttgtctattc
     8521 aaggaataaa tcagcgaaac cttattaaat ttcagacttg gtttttaata atcacctcgc
     8581 ctataatcgt tcaattaggt acaattaatt ataaggaaat ggaagaccac tactaaaagg
     8641 ggctgataaa atgcaaaata aagaatatta tgaattgata gaaagagata acacaaatcc
     8701 aaaagacaac gagcgcagag ccttgtttac tatactgagt gaaaatgaag aattatattc
     8761 aaaaattgat agtctttatg attttgagaa tcactggatt aatgacgatt gttttgaaaa
     8821 gattgatttt agtaatggta caagaaaatt agttcaatta gcgttcaatc tttataacaa
     8881 taatccttct cccacaccat tagaaatttt ttctagttta gatagtgaca attatgattt
     8941 agcaatgaaa gcaattaata ttcgatttaa taaaatataa actaactaaa aaaggagcta
     9001 acagacaagc attagtctgt ggcccctttt tagtttagca aataattaaa tttttttgta
     9061 tgtatgtgtg taagtttttt gcttcttctt gttgatcaat gatcgattgt tctttatcgc
     9121 atgcgccaaa aaatatatag tcaatttcgc ttaataaatt tctaagtagg gcattttttc
     9181 tacagttact taatttttct gagtgaataa tcgctttata attagcctgg taattttcaa
     9241 gtatgcctat caaagtaatc cttccttctg gttatatatt tgcctttaat tataactaat
     9301 ttaaatttta taactacctc ttttaaacca tgaaaccatt attttttaag tgaaaccatt
     9361 tcttgttcaa atataatggt ttcacttctg aattttttaa agggcttact tacactccaa
     9421 taaaaacttt ttggagtatg cgctaagatc caaatcaaat tcaagggcgc acttacacac
     9481 gataaaaaat atcgtgtttg tgctaaagaa atgtgtgaaa aatcgctccg caattttaaa
     9541 aattcgttgc actcatgtaa aagatccgag tgattttttt agatgatctc tattttaatc
     9601 agtcatttgt tttt
//
