LOCUS       NC_015688              11123 bp    DNA     circular CON 08-JUN-2013
DEFINITION  Clostridium acetobutylicum DSM 1731 plasmid pSMBb, complete
            sequence.
ACCESSION   NC_015688
VERSION     NC_015688.1  GI:337738947
DBLINK      Project: 68293
            BioProject: PRJNA68293
KEYWORDS    .
SOURCE      Clostridium acetobutylicum DSM 1731
  ORGANISM  Clostridium acetobutylicum DSM 1731
            Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
            Clostridium.
REFERENCE   1  (bases 1 to 11123)
  AUTHORS   Bao,G., Wang,R., Zhu,Y., Dong,H., Mao,S., Zhang,Y., Chen,Z., Li,Y.
            and Ma,Y.
  TITLE     Complete genome sequence of Clostridium acetobutylicum DSM 1731, a
            solvent-producing strain with multireplicon genome architecture
  JOURNAL   J. Bacteriol. 193 (18), 5007-5008 (2011)
   PUBMED   21742891
REFERENCE   2  (bases 1 to 11123)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2011) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 11123)
  AUTHORS   Bao,G. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2011) Chinese Academy of Sciences, Institute of
            Microbiology, NO.1 West Beichen Road, Chaoyang District, Beijing,
            Beijing 100101, China
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to CP002662.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..11123
                     /organism="Clostridium acetobutylicum DSM 1731"
                     /mol_type="genomic DNA"
                     /strain="DSM 1731"
                     /culture_collection="DSMZ:DSM 1731"
                     /db_xref="taxon:991791"
                     /plasmid="pSMBb"
     gene            944..1069
                     /locus_tag="SMB_L001"
                     /db_xref="GeneID:10844970"
     CDS             944..1069
                     /locus_tag="SMB_L001"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical Protein"
                     /protein_id="YP_004638394.1"
                     /db_xref="GI:337738948"
                     /db_xref="GeneID:10844970"
                     /translation="MGKEFANDYYDRRIQEGVGDEQGEKELTEILGHTRAEVLDS"
     gene            complement(1095..2135)
                     /gene="repB"
                     /locus_tag="SMB_L002"
                     /db_xref="GeneID:10844962"
     CDS             complement(1095..2135)
                     /gene="repB"
                     /locus_tag="SMB_L002"
                     /codon_start=1
                     /transl_table=11
                     /product="Replication protein"
                     /protein_id="YP_004638395.1"
                     /db_xref="GI:337738949"
                     /db_xref="GeneID:10844962"
                     /translation="MDKEYLVTKSNYFIMNSSYDLSLEEQKIILTLASMVQPTDEEFK
                     PYKFKINDFMILLGVDTKTKYTKIPKITKELMKKVFEIQEGDILIQTAWLSGAKYKKG
                     TGYVELTFSPYLKPYMLKLNNMFTKYKLANILNMKSKYSPRIYEILKCNEFKKQGYIE
                     IDIEDLRKLLKAEDIYPMYADFKRKIINQTQKELNKLSDIKFEFEEIKTGRKVTAIRF
                     YINSNIKAKDETSVTKLDTEEPERLEDSDKYIKEIKNIIANHKITSLEARKIYHSSKG
                     NLKQIHKVYNYFKNRKLDNFVGTMISMVKPGVFQEPKANIQTDDFNNYSQRQYNFNDL
                     EKGLLGWQNSKE"
     misc_feature    complement(1476..2129)
                     /gene="repB"
                     /locus_tag="SMB_L002"
                     /note="Initiator Replication protein; Region: Rep_3;
                     pfam01051"
                     /db_xref="CDD:216266"
     gene            complement(2778..3344)
                     /locus_tag="SMB_L003"
                     /db_xref="GeneID:10844969"
     CDS             complement(2778..3344)
                     /locus_tag="SMB_L003"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical Protein"
                     /protein_id="YP_004638396.1"
                     /db_xref="GI:337738950"
                     /db_xref="GeneID:10844969"
                     /translation="MKYIKNKIILFLTILLSLNIAFSNNILAATNTQVGNRPSYVGKN
                     GCIVEYKPLDYMDTGIEIIHAQDYYMSPQAAHNFADDLTPSRTESLLEFLSTLVTIPL
                     SAGLSTALGAYFFLETDGDTALANKIKDQIQKSYNDGNGGYIRVTVKDCEMKRGGVSM
                     INYDTADWNGTDVSFLSGFKVQKTYRLN"
     gene            3917..4999
                     /locus_tag="SMB_L004"
                     /db_xref="GeneID:10844963"
     CDS             3917..4999
                     /locus_tag="SMB_L004"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical Protein"
                     /protein_id="YP_004638397.1"
                     /db_xref="GI:337738951"
                     /db_xref="GeneID:10844963"
                     /translation="MLKLLKKFYFICICSICICSTSFIANAQNIDEAHSSINTIARSF
                     ASNTIKWDDIDIYNIKNLYDINNKLVAYSIDIKNNKNGLLGYEILSAISEDDPVLEFS
                     KTKCSPYNKVENGYKCIYEGALNYYYQNKTTIYNIQNKTTLNEKEIILLRKADKNKEY
                     KSDKTNKVLKSNNLVSSFRNKSQDTTNGKVQKILENVPDELWYRGCTPTAVAMVLEYD
                     FYNDTPEFQPLTDDLANAFGTNSDGFTTIDDHICDSIKSVMKKYGVNNIWCQLDGQGK
                     DNSTYEEYVNEINNNHPVVVNLYGSKETSYGYPDGFKDHSCAGIGYEYTDNEKFIVIH
                     DDALDDSVYCDFNSSDLGINQWLYIH"
     misc_feature    4502..4921
                     /locus_tag="SMB_L004"
                     /note="Peptidase_C39 like family; Region: Peptidase_C39_2;
                     pfam13529"
                     /db_xref="CDD:222201"
     misc_feature    order(4532..4534,4859..4861,4919..4921)
                     /locus_tag="SMB_L004"
                     /note="putative active site [active]"
                     /db_xref="CDD:239073"
     gene            5035..6048
                     /locus_tag="SMB_L005"
                     /db_xref="GeneID:10844964"
     CDS             5035..6048
                     /locus_tag="SMB_L005"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical Protein"
                     /protein_id="YP_004638398.1"
                     /db_xref="GI:337738952"
                     /db_xref="GeneID:10844964"
                     /translation="MINKKALKIASLTSIFTLLFTSFTNSQIIFAANTNATKKHYDIS
                     YIYSNKSSTKEKLEYANSKNYDSSKKVRLNEFDLYKEIDNKKGLDSTSQNSMVKKYKD
                     TIKKLNSKNDTELKNLGFDSSRITALRKSKLALNNNNLEQIGSTLTVSVNLDSYYHDM
                     QYEPNSPKFKTLIYAIFSWSWSQAPLVTDTDGLGVEWLSNSQDKLQVYYTSDVVDYYN
                     AIYNTVTSSVDYADQALNNETINKNGLFFTFPFQLNKQAKYKVKNALNGISMNVLVNT
                     NAYVDDFTLYGLYAHSLNLSNPTFSITDNGVDVDSSYKSNAELKPISQEFKYSEWDPN
                     NNQ"
     gene            6561..6683
                     /locus_tag="SMB_L006"
                     /db_xref="GeneID:10844965"
     CDS             6561..6683
                     /locus_tag="SMB_L006"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical Protein"
                     /protein_id="YP_004638399.1"
                     /db_xref="GI:337738953"
                     /db_xref="GeneID:10844965"
                     /translation="MSKRPSVVFQVNEVLRKAFHECFGRSRHADKHNDMNNGKE"
     gene            complement(7286..7834)
                     /locus_tag="SMB_L007"
                     /db_xref="GeneID:10844966"
     CDS             complement(7286..7834)
                     /locus_tag="SMB_L007"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical Protein"
                     /protein_id="YP_004638400.1"
                     /db_xref="GI:337738954"
                     /db_xref="GeneID:10844966"
                     /translation="MVKQEFNKLDIKEQLAYVNRALMDGKSLRGISTSLQISKTIIRD
                     RFQKIGYIFNAEKRQYVKDTDILHKGQTIKNKTIRNAEYKGNTCVFNADDTSKIVYIL
                     KNYEDIKELLAWFNKQKNVVEPQNLKINRNRLNGAVKITTVRLYINVWEKFKSFMKQY
                     QEYKSKDLVTMALLEFMDKYKK"
     gene            complement(8089..9045)
                     /locus_tag="SMB_L008"
                     /db_xref="GeneID:10844967"
     CDS             complement(8089..9045)
                     /locus_tag="SMB_L008"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical Protein"
                     /protein_id="YP_004638401.1"
                     /db_xref="GI:337738955"
                     /db_xref="GeneID:10844967"
                     /translation="MIHTIQYSSIPFYDDIDLIRNSFKTVKKDGQLVYYSRYKAIDFK
                     YYSFFNVLHTKINLNELLNKDVITDQDYNAVLKEYQNQFYDIFKYTNALEQLNRIDFK
                     CDVITDYKTLYIKLLKKSSDNYKSLKQYSKYKSSVYYNSKSMNINIYDKLEQLINTGQ
                     DKLIDISKYKNMLRFEVQLKRNKLYYLERTCGMTRELSNYFSQKDHDYWINEGLKKLI
                     HNGDYYNIYHSEKILKEHYTNNMVNKLITLQKDISINGISEARENYNNTTFNNYINKL
                     QSAGVNPIPIPKGEGLTRLSNIFNFTNDNIYLLDNYNLRSVA"
     gene            complement(9727..10422)
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /db_xref="GeneID:10844968"
     CDS             complement(9727..10422)
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /codon_start=1
                     /transl_table=11
                     /product="Resolvase Family Protein"
                     /protein_id="YP_004638402.1"
                     /db_xref="GI:337738956"
                     /db_xref="GeneID:10844968"
                     /translation="MNKIYGYCRISTSKQSIERQHRNILASYPTAVIIDEVYTGTKIY
                     ERKEFNKLLKQVTKGDTIVFDSVSRMSRDAEEGFKLYEKLFNKGIELVFLKEQHINTA
                     TYKKALTNNIKLTGTAVDSILKGVNEYLMELAKEQIIIAFNQSEKEVKDLHQRTKEGI
                     ETARLNGKQIGQKQGVKLTTKKSINTKQDIIKYSKDFQGTLKDIEVMKLVGLARNTYY
                     KYKRELVQELEGK"
     misc_feature    complement(9736..10416)
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /note="Site-specific recombinases, DNA invertase Pin
                     homologs [DNA replication, recombination, and repair];
                     Region: PinR; COG1961"
                     /db_xref="CDD:224872"
     misc_feature    complement(9946..10413)
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /note="Serine Recombinase (SR) family, Resolvase and
                     Invertase subfamily, catalytic domain; members contain a
                     C-terminal DNA binding domain. Serine recombinases
                     catalyze site-specific recombination of DNA molecules by a
                     concerted, four-strand cleavage and...; Region: SR_ResInv;
                     cd03768"
                     /db_xref="CDD:239737"
     misc_feature    complement(order(10207..10209,10216..10221,10390..10392,
                     10396..10398))
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239737"
     misc_feature    complement(10390..10392)
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /note="catalytic nucleophile [active]"
                     /db_xref="CDD:239737"
     misc_feature    complement(order(9985..9987,9997..10002,10054..10059,
                     10222..10224))
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /note="Presynaptic Site I dimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    complement(order(9979..9981,9988..9990,9997..10002,
                     10057..10062,10069..10071,10186..10191,10204..10206))
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /note="Synaptic Antiparallel dimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    complement(order(9958..9960,9976..9978,9985..9987,
                     9997..9999,10054..10059,10066..10071,10126..10128,
                     10132..10137))
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /note="Synaptic Flat tetramer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    complement(order(9958..9960,9976..9978,9985..9987,
                     9997..9999,10054..10056,10135..10137))
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /note="Synaptic Site I dimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    complement(order(9955..9960,9982..9984))
                     /gene="pinE"
                     /locus_tag="SMB_L009"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:239737"
ORIGIN      
        1 aaactaaata attgattttc aaaactaaat aattgatttt ttggacgtag aaagttgtat
       61 atttaactat gtagggtata atatttatta gataaataaa taggctatat agaaacagtt
      121 ctttgaaaat tggcaaattt tctagaatgc tattatttgt agtgagagaa gttaaatgca
      181 tgttttgaaa tggcaccata gccacaaaaa tgtcatttaa cgaaaacaaa agtaatgctc
      241 cggttcggca aaactggagc attacaattt tgtatataaa aaactttcag cgtatccctt
      301 gtatatttgg caattaattt ctatcggcaa atagaaatct aaagtttttt atatctagga
      361 taggtaattg tttttatata tatgtagcgg ataagtatcc tacatacata aatgagcaaa
      421 caatttgaat tagctttata ttctttttga attttttatt actagacata taatccagta
      481 acattaaaat tgcacagcta atgagataaa taaaattgac tatataaatc agctcctctc
      541 ttacaaggga cgctgcatac atattataat acaaaaaaat taattattac ccctatgcaa
      601 taaaaaaagt atgatttgca aaattctatt ttttagcaaa ctggctagaa taaagggttt
      661 tgagctttaa aaaaatcgga aaaattattt tagtagaaat gtttcacaat gtttcacaaa
      721 gctctatagt tttattatat gttaaaattc agtcccaaaa acaataaggg gtagcgccaa
      781 cattgtcggt ttggttggcg ctacccctac ttataattaa tttaaaaact ctttaagtga
      841 acatgataga ctttttatta ataaatcaga ttcatatgaa aaaacttttt aaaggattag
      901 agatataata tctcactatt atacctattg tggtgttcat atcatgggaa aagaatttgc
      961 taatgattat tatgacaggc gtattcagga aggtgttgga gatgaacagg gtgaaaaaga
     1021 gttgactgaa attttaggcc atactagagc agaagtttta gattcatagc taaaataaga
     1081 gggttcaata ccctctattc tttgctattt tgccacccta ataatccttt ttctaaatca
     1141 ttaaaattgt attgtctttg actatagttg ttaaaatcat ctgtttgaat gttagcttta
     1201 ggctcttgaa aaactcctgg ctttaccatg cttatcattg ttccaacaaa gttatctaat
     1261 tttctgtttt taaaataatt atatacctta tgtatttgtt ttaaatttcc cttggaacta
     1321 tgatatattt tcctagcttc caatgatgta attttatgat tagcaattat atttttaatt
     1381 tcttttatgt acttatcact atcttctaat ctttctggct cttcagtatc taattttgtt
     1441 acggatgttt catctttagc ttttatatta gagtttatat aaaatctaat tgctgtaact
     1501 tttctccctg ttttaatttc ctcaaattca aattttatat cacttaattt atttagttct
     1561 ttttgcgttt gattaattat ttttctttta aaatcagcat acataggata aatatcttca
     1621 gcttttaata atttacgaag atcttctata tctatctcta tataaccttg ttttttaaat
     1681 tcattgcact ttaaaatctc atatattcta ggtgaatatt tacttttcat atttaatata
     1741 ttagccaatt tatatttagt aaacatatta ttaagtttta gcatatacgg ctttaaatat
     1801 ggactaaaag ttaattcaac atatccagta ccctttttat attttgcgcc acttaaccat
     1861 gctgtttgaa ttaaaatatc accctcttgg atttcaaaaa cttttttcat aagttctttt
     1921 gttatcttag gtattttcgt atattttgtt ttagtatcga cccctaataa tatcataaaa
     1981 tcattaattt taaatttata aggtttaaat tcttcatctg ttggttgaac catacttgct
     2041 aaagtaagta taatcttctg ttcttctaaa cttaaatcat aacttgaatt cataataaaa
     2101 tagtttgatt tagttactaa atattcttta tccataaaaa ccccctaaaa tatggtatca
     2161 cactaactat gactatgtca aattatagtc atagttaggt acgcaaaagt catagttagg
     2221 tacgcaaaag tcatagttag gtacgcaaaa gtcatagtta aaggtacgca aaagtcatag
     2281 ttaggtacgc aaaagtcata gttaaatttt caaacctata cataccaata ctttaaagct
     2341 tgtctaaaac atataaaaca aaaagatata aaacatataa aacaacaact gttattgttg
     2401 ttccaaaaat atagattaat ttaatgtacg caaaagtatt attttgggta gccatttgta
     2461 tagttaaaat attgtaaaaa tgtgatataa atattgtagg aggtatgtat tataaatagg
     2521 tttcaatttg atgcattaga tttcactgta caggtaaatt acataaatga tgaattaatt
     2581 aaaggttcca cattgtacat ccaaaactaa gatatgaaaa gatataaata atggatgtac
     2641 aacgataaaa gataggttta ttaaaagcgt ttataaaagg tcagtgagtt ttatattaaa
     2701 aaagtactat atgaatttta aattcatata gtactttcta ctgttaatta aaactatcat
     2761 ttatattcat aataatatta atttaaacga tatgtttttt gtaccttaaa accgcttaag
     2821 aagcttacat ctgtaccatt ccaatccgca gtatcgtagt taatcatgct aacaccacca
     2881 cgtttcattt cgcaatcttt tacagttaca cgaatatacc caccattacc atcattatag
     2941 cttttttgaa tttgatcttt tattttattt gcaagagcag tatctccatc agtttctaaa
     3001 aagaagtatg caccaagagc agtacttaat ccagcactaa gaggtatagt tactagtgta
     3061 gacaagaatt ctaaaagcga ttctgttctt gatggtgtta aatcgtcagc aaaattatgt
     3121 gcagcctgag gagacatata ataatcttga gcatgaatta tttcaattcc cgtatccata
     3181 taatctaacg gtttatattc tacaatgcaa ccattttttc caacataact tggtctattt
     3241 ccaacttgag tattagttgc tgctaaaata ttgttactaa aagcaatatt taaagataaa
     3301 agtatagtta gaaataggat tattttgttt tttatatatt tcaaagtacc accccttttt
     3361 aattacaata ataccatata ttatgcaaaa agtaaaatga tgtataatat atattttgac
     3421 tttcatgtat tattatggta taaaatatat aaacaagtgt aaggagagaa atactatgtc
     3481 tgttgtaaaa tgtactaatt gtaataataa atttaaatgg tatcaaattg tagtaagcat
     3541 attcaataaa tcacatacta ttaagtgtaa aaattgtaat agtgatttta aattaacaca
     3601 taaatcatat attataggaa gtttactttc tgtcgtaatt ccattaacta taacaataat
     3661 gtatataatt tttaataata accagcctcc gatatcactt tttttattta tattattaat
     3721 attaatattt agtatggttc ttccgtttat tatgaagtat gaaaaactga attagtaggt
     3781 aaattcacaa aaagtcaaat ttatgcatta ttttgacttt tttttattta tgtggtaaat
     3841 tagttatcga attcaaatat gtatttgttt tacataaata catataaaaa ctatataagt
     3901 aaaaaggaat gatgttatgc taaaattatt aaaaaaattt tattttatat gtatatgttc
     3961 tatatgtata tgttccacct catttattgc aaatgcacaa aatatagatg aagcacatag
     4021 cagtatcaac actatagcta gaagctttgc aagtaatact ataaaatggg atgatattga
     4081 tatttataat attaaaaact tatatgatat taataataag ttggtagcgt atagtataga
     4141 tattaaaaat aataagaatg gcttactggg atatgaaatt ctaagtgcaa tttctgaaga
     4201 tgatccagta ctggaattct caaaaacgaa atgttctcct tacaacaaag ttgaaaatgg
     4261 ttataaatgc atatatgagg gggctttaaa ttattattat caaaataaaa cgactattta
     4321 caatatacaa aacaaaacta ctttaaatga aaaagaaatt attctgctaa gaaaggcaga
     4381 taaaaataaa gaatataagt cagataaaac taataaagtc ttaaaatcaa ataatttagt
     4441 atcttcattt cgtaataaat cacaagatac tactaatggc aaagtacaaa aaattttaga
     4501 aaatgtgcct gatgaacttt ggtatagagg gtgtacacct acagctgttg caatggtatt
     4561 agaatatgat ttttacaatg atactccaga gtttcaacca ttaactgatg atttagcaaa
     4621 tgcttttgga acgaattctg atggatttac aacaatagat gatcacatat gtgattcaat
     4681 aaaaagtgta atgaaaaaat atggtgtcaa taatatatgg tgtcaattag atggacaagg
     4741 taaagataat tcaacctatg aggaatatgt taatgaaata aataataatc atcctgttgt
     4801 tgttaatctt tatggaagta aagaaacttc atatggttat ccagatggtt ttaaagatca
     4861 tagttgtgct ggaattggct atgaatatac tgataatgaa aaatttattg tgattcatga
     4921 tgatgcttta gatgatagtg tttattgtga ctttaatagt tcagatttag gtataaacca
     4981 atggctttat atacattaat ttaaaatttt tttataatga aagagggtac ataaatgata
     5041 aataaaaaag cattaaaaat agcatcttta actagtattt ttacattact ttttacttca
     5101 tttactaatt cacagattat tttcgctgct aatacaaatg ctacaaaaaa acactatgat
     5161 atttcatata tatattctaa taaatcttct acaaaagaaa aattagaata tgccaattca
     5221 aaaaattatg atagttcaaa aaaagtaaga ttaaatgaat ttgacttata taaagagatt
     5281 gataataaaa aaggtcttga ttctacatca caaaattcaa tggtgaaaaa atacaaagat
     5341 acaataaaaa agttaaattc caaaaatgat actgaattaa aaaatttagg atttgactcc
     5401 tcaagaatta ctgctttaag aaaatctaaa ttggcattaa ataataataa tttagaacag
     5461 ataggaagta cgcttacagt atccgttaac ttagattcat attatcatga tatgcaatat
     5521 gaaccaaaca gcccaaagtt taaaactcta atttatgcta tatttagctg gtcatggtct
     5581 caagcaccac ttgttacgga tactgacgga cttggagtag agtggttgag taattctcaa
     5641 gataaattac aagtttatta tactagcgat gtagtagact attataatgc tatatataat
     5701 actgtaacta gtagtgtcga ttacgcagat caagctttaa ataatgaaac tataaataaa
     5761 aatggtttat tttttacttt tcctttccag cttaataaac aagctaaata caaagtgaaa
     5821 aatgcactaa atggtatttc gatgaacgta ctagtaaata ctaacgcata tgttgacgat
     5881 tttactttgt acggtctgta cgctcactca ttaaatttaa gtaatcctac tttttcaatt
     5941 acagacaatg gtgttgatgt agatagtagt tacaaatcaa atgctgaatt aaaaccaata
     6001 tctcaagaat ttaaatatag tgaatgggat ccaaataaca accaataaaa actaaattca
     6061 acataatatc tattgtgttg aactaataaa aaggtaccag ctgggtgcaa gaaacatcag
     6121 aaattacact tttattgtag taaatttaat taaataaaag tgtaatttaa tatcgaaaat
     6181 ctaaaggaga aatttttatt tcttctttag atttttgctt tttatcgttt gaagctgtac
     6241 tagtggtaat cataaaatga ttactttgta tttatttctt tattcagata acaaagcaaa
     6301 caagaaaaaa ctttgagctt ttaagctcgt aaactataac ttttgttgta gctatattcc
     6361 atctgacgaa gtggaataat atgtgttggg ttttgtaaca tacaaaactc gtttggttgt
     6421 ttatatattc ttaatttcgt tactttttag cttatcatac tgtacggatt aagagatctt
     6481 tataaaacat cttaatccgc tatagctgtt tattttaaat gctttaatgc atatataata
     6541 catttatgag gtgataacaa atgagtaaaa gacctagtgt tgtattccag gtaaatgaag
     6601 tattacgaaa agcctttcat gaatgctttg gaagaagcag acacgctgac aagcataatg
     6661 atatgaataa tggtaaagag taggatacct atactaaaaa taaaatatac agtcagaaga
     6721 cctataaagc tacaaataaa atttgtgtag cctttgttta acattgtagt tgatgccttt
     6781 aacattgtgt aggtgtaaca cttatattaa attaaaaaca tgcatataac atctataccc
     6841 ttaaaactca tttaaacgct attttagcca catataaagt tcaacatata aaaccactat
     6901 acatgaattt aaatgcgaat tagggactgt ttgatacatt ccagcatgta attttaacat
     6961 tgtagtcgat gtctataaaa ttgatatttt atattaaaat tcttatgttg ctgctatcat
     7021 aaaaatttaa tcaaaatcac aaataaaaaa gcacctataa taatataagt gcttggaaat
     7081 atattgttca tactcatatt taaatttttt agctcttgat agaactagcc ttgcagtacc
     7141 tctaaaacat ttaaaacaac aacaagggta cacaaatgta atagttaaat taaaccgaca
     7201 tttagttacc ttaaatcttt attgttgttg taataattta atattaaaaa actgaatagt
     7261 aaaaatctat ccagttcata acatattatt ttttatattt gtccatgaat tccaataaag
     7321 ccatagtaac taaatcttta gatttatact cttggtattg cttcataaaa cttttaaact
     7381 tttcccaaac attaatgtat aatcttaccg ttgttatctt aactgctcca tttaatctat
     7441 ttctattaat ttttagattt tgtggctcta caacattttt ctgcttgtta aaccacgcca
     7501 gcaactcttt tatatcttca taatttttaa gtatatatac tattttactt gtatcatctg
     7561 cgttaaacac acatgtatta cctttatatt cggcatttct tattgtcttg tttttaatag
     7621 tttgaccctt atgtaatatg tctgtatcct tgacgtactg ccttttctct gcattaaata
     7681 tatatcctat tttttgaaat ctatctcgga ttatggtctt actaatttgt aaactggtac
     7741 taataccacg tagactctta ccgtccatta atgccctgtt tacatatgcc aactgctctt
     7801 tgatatctaa tttattaaac tcttgcttaa ccattccact acccccaaag aaatatgaat
     7861 acattacaaa tatattcata ttatacatat attactataa tgttacaata atataattaa
     7921 atggtctctt gcttgaaaaa ttaaaattag tgttaatgca gctacttaca agaatactga
     7981 aaagatatga ggtattaaag tttgtaaaca gcccccctat atggatgttt accgtagaga
     8041 tatattaata taataaaaaa aagaaggcta tttaccttct ataaattgtt atgctactga
     8101 tcttaaatta taattatcta atagatagat attatcattt gtgaaattaa atatgtttga
     8161 taatctagtt aatccttcac cttttggtat tggtatcgga ttaacccctg ctgattgtaa
     8221 cttatttatg taattattaa aagtagtatt attataattt tctcttgctt cactaattcc
     8281 attaatgctt atgtccttct gtaatgttat tagtttatta accatattat ttgtataatg
     8341 ctcttttagt attttttcag aatggtatat attataataa tcaccgttat gtattaattt
     8401 tttcaatccc tcattaatcc aataatcatg gtctttttga gaaaaataat ttgataattc
     8461 tcttgtcatt ccacatgtac gttcaagata ataaagttta ttccttttga gttgaacttc
     8521 gaatcttagc atatttttat attttgatat atcaatcaat ttatcttgcc ctgtattaat
     8581 tagctgttct aacttatcat atatgttgat gttcatggat tttgaattgt agtaaaccga
     8641 actcttatac ttactatact gctttaatga tttataattg tcactacttt tctttaatag
     8701 tttaatatat aatgttttat aatccgttat tacatcgcac ttaaaatcaa ttctattaag
     8761 ttgctctagt gcatttgtat atttaaaaat atcataaaat tgattttggt actctttcaa
     8821 tactgcatta taatcttggt ctgtaatcac atctttattc aataattcat ttaaattaat
     8881 ttttgtatgc aatacattaa aaaaactata atatttaaaa tctattgcct tatatcttga
     8941 ataatagact agttgtccat ctttttttac tgttttaaaa ctatttctta tcaagtctat
     9001 atcatcataa aacggtatac ttgaatattg tattgtatgt atcatgtaaa gtaattcctc
     9061 cttgtatttt gtatttttaa aagtcgggaa aaatacttta ctaactatat ttaatttttt
     9121 attagtatta ctgtgctttt ttaatatatt tattttttat ttaatgtatt tttctatctg
     9181 tacttttata tatttatagc aaaagtttac tttgactatc tttttatcta ttgatacaat
     9241 aatctttagt tagtaaagtg tgtagtggtc gttaccagct acccctaata tgtattattt
     9301 tgtatatgct ttttcgtgtt ggcttaggca tattttttta tttcttatag aattttgacc
     9361 atttttacaa tatctagtag ttcaatttaa ccacttcctt tcacaataaa taataaaaaa
     9421 aggagttaat tatatagaca attacctaat aatacaatta aatttatata aagttcgaat
     9481 ttaatacagc atacacaaat caactttttt gaatgtatat tactaataaa tattaaattc
     9541 aaaaattcta attataaatt taaattgcat tattagagta tcgcttctat ataatcgact
     9601 cctttttgcg ttatattcta taaatttaat ttgcaattat taagttacct ttaataataa
     9661 cataatatag tacaacttgt caatatattc ttatactata tatattaata taataaaaaa
     9721 agaaggctat ttaccttcta attcttgaac caattccctt ttatatttgt aatatgtatt
     9781 tcttgcaagt ccaaccaact tcattacttc tatatctttt aatgttcctt ggaagtcctt
     9841 gctgtattta ataatatctt gttttgtgtt aatgctcttc ttagtagtta attttactcc
     9901 ttgtttctgt cctatctgtt taccatttaa tctagctgtt tctatacctt ctttagttct
     9961 ttgatgcaga tctttaactt ctttttctga ttggttaaat gctattatta tttgttcctt
    10021 agcaagttcc attaaatact catttacacc ttttaatata ctatcaactg ccgtacctgt
    10081 taactttatg ttatttgtta atgctttctt atacgttgct gtgttaatat gttgctcttt
    10141 aagaaacact aactctatac ccttgttaaa tagtttctcg tatagtttaa atccttcttc
    10201 tgcatctcta ctcatacggc taacgctgtc aaatacaatt gtatcccctt tagttacttg
    10261 ctttaataac ttattaaact ctttacgttc atatatctta gtacctgtat atacttcatc
    10321 tattattact gctgttggat aacttgctaa tatgtttctg tgctgacgtt ctatactctg
    10381 cttacttgta cttattctac aatatccata tatcttattc ataattcata tcccctttag
    10441 tactttagta ttaaatttaa caaccgtttc ttttgatact ctaatgatac cagctctatt
    10501 tcttaatgtc aataagtttt aatacttttt attaatacgt tatttttaat acttttatat
    10561 ataataccgt cttactatcg cattataaaa aaatagcact tcattatgat agatcaaatt
    10621 aaagtaaata aaagttatat cggcaacata tcggtataat ctatgataat tatcaaataa
    10681 tggttattat agttcatttt aacttaatat agagttttga tatgacaata tataagcctc
    10741 gacaaaatgg cttgaatact acattcgtaa gcattattaa taaagtatcg aatatttaag
    10801 gggcttgtgt aggtgtaaca cttatattaa attaaaaaca tgcatataac atctataccc
    10861 ttaaaactca tttaaacgct attttagcca catataaaat tcaacatata atggctggca
    10921 aactaataac tctttaaaag gtactatttt agggtttaat ttatttaatg ggtaaatgga
    10981 aaatgaagaa ggatgtaata cagttgaaat ctttcaaata gatgagatag aaaatatttt
    11041 attgaagcta taaagataag atttggtgat cttttttagt aaaagatact atactgtatt
    11101 ttaaactaaa taattgattt tca
//
