LOCUS       NC_017064               5289 bp    DNA     circular CON 08-JUN-2013
DEFINITION  Helicobacter pylori ELS37 plasmid pHPELS37, complete sequence.
ACCESSION   NC_017064
VERSION     NC_017064.1  GI:383750634
DBLINK      Project: 158157
            BioProject: PRJNA158157
KEYWORDS    .
SOURCE      Helicobacter pylori ELS37
  ORGANISM  Helicobacter pylori ELS37
            Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
            Helicobacteraceae; Helicobacter.
REFERENCE   1  (bases 1 to 5289)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAR-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   2  (bases 1 to 5289)
  AUTHORS   Bertoli,M.T., Kersulyte,D., Pascasio,M.A. and Berg,D.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUL-2011) Molecular Microbiology, Washington
            University Medical School, 4940 Parkview Place, Saint Louis, MO
            63110, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to CP002954.
            Annotation was added by the NCBI Prokaryotic Genomes Automatic
            Annotation Pipeline Group. Information about the Pipeline can be
            found here:
            http://www.ncbi.nlm.nih.gov/genomes/static/Pipeline.html. Please be
            aware that the annotation is done automatically with little or no
            manual curation.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5289
                     /organism="Helicobacter pylori ELS37"
                     /mol_type="genomic DNA"
                     /strain="ELS37"
                     /isolation_source="male cancer patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1055527"
                     /plasmid="pHPELS37"
                     /country="El Salvador: rural region"
     gene            join(5257..5289,1..1296)
                     /locus_tag="HPELS_08409"
                     /db_xref="GeneID:12020890"
     CDS             join(5257..5289,1..1296)
                     /locus_tag="HPELS_08409"
                     /note="COG0675 Transposase and inactivated derivatives"
                     /codon_start=1
                     /transl_table=11
                     /product="IS606 transposase"
                     /protein_id="YP_005425737.1"
                     /db_xref="GI:383750635"
                     /db_xref="GeneID:12020890"
                     /translation="MKVNKGFKFRLYPTKEQQDKLQHCFFVYNQAYNIGLNLLQEQYE
                     TNKDLPPKERKWKRSSELDKAIKHHLNARGLSFSSVIAQQSRMNVERALKDAFKVKNR
                     GFPKFKNSKSAKQSFLWNNQGFSIKESDEERFKTFTLMKMPLLMRMHRDFPPNFKVKQ
                     ISISCSHRKYFVSFSVEYEQDITPIKNPKDCVGLDLNILDIACSCGINNHEKLTDFKQ
                     YQTDMKELLGIEIDKELDTKRLIPTYSKLYSLKKYSKKFKRLQRKQSRRVLKSKQNKT
                     KLGGNFYKTQKKLNQAFDKSSHQKTDRYHKITSELSKQFELIVVEDLQVKNMTKRAKL
                     KNVKQKSGLNQSINNTSFYQIISFLDYKQQHNGKLLVKVPPQYTSKTCHCCGNINHKL
                     KLNHRQYWCLECGYREHRDINAANNILSKGLSLFGVGNIHADFKEQSLSC"
     misc_feature    join(5257..5289,1..108)
                     /locus_tag="HPELS_08409"
                     /note="Helix-turn-helix domain; Region: HTH_OrfB_IS605;
                     pfam12323"
                     /db_xref="CDD:221531"
     misc_feature    join(5263..5289,1..1254)
                     /locus_tag="HPELS_08409"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG0675"
                     /db_xref="CDD:223747"
     misc_feature    199..963
                     /locus_tag="HPELS_08409"
                     /note="Probable transposase; Region: OrfB_IS605;
                     pfam01385"
                     /db_xref="CDD:216470"
     misc_feature    862..1104
                     /locus_tag="HPELS_08409"
                     /note="transposase, IS605 OrfB family, central region;
                     Region: tspaseT_teng_C; TIGR01766"
                     /db_xref="CDD:233563"
     gene            1424..1591
                     /locus_tag="HPELS_08384"
                     /db_xref="GeneID:12020891"
     CDS             1424..1591
                     /locus_tag="HPELS_08384"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_005425738.1"
                     /db_xref="GI:383750636"
                     /db_xref="GeneID:12020891"
                     /translation="MKSIRLFGFFSCFLLSKIAYNQRKAKNRLMTTYKLKNAKNKSTQ
                     AKISGFTQEKK"
     gene            complement(1576..2280)
                     /locus_tag="HPELS_08389"
                     /db_xref="GeneID:12020892"
     CDS             complement(1576..2280)
                     /locus_tag="HPELS_08389"
                     /note="COG3177 Uncharacterized conserved protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative cAMP-induced filamentation protein"
                     /protein_id="YP_005425739.1"
                     /db_xref="GI:383750637"
                     /db_xref="GeneID:12020892"
                     /translation="MLTKLIEKLNHERKNAIKNGIYHLIQIKFSYNSNRIEGSGLTYE
                     QTAHIFDKSVLITEKNANIKLDDIFETINHFECVNYLLENYKKPLSLEYFKTLHKILK
                     KNCSDEVIGGFKKRPNFVGNSATTRPKLVESELTNLLQRYHSLTATSLENIIDFHVAF
                     EKIHPFSDGNGRVGRLVMFKECLKNNIMPFIIENEHKAFYYRGIKEYDNTKGYLKDTI
                     LQSQDNFNEMVSYFFS"
     misc_feature    complement(<1636..2220)
                     /locus_tag="HPELS_08389"
                     /note="Fic family protein [Function unknown]; Region:
                     COG3177"
                     /db_xref="CDD:225718"
     misc_feature    complement(1747..2019)
                     /locus_tag="HPELS_08389"
                     /note="Fic/DOC family; Region: Fic; pfam02661"
                     /db_xref="CDD:217170"
     gene            complement(2293..3936)
                     /locus_tag="HPELS_08394"
                     /db_xref="GeneID:12020893"
     CDS             complement(2293..3936)
                     /locus_tag="HPELS_08394"
                     /note="COG5527 Protein involved in initiation of plasmid
                     replication"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein A"
                     /protein_id="YP_005425740.1"
                     /db_xref="GI:383750638"
                     /db_xref="GeneID:12020893"
                     /translation="MPMNTNFKQLRKQELELRKLLEELDTLPQTPQIKLQKQKIQTYI
                     DKITPSILSGFNQKFKEITEKLPNEFEKEKPTPTKEPQTTPTPCKDLVVSTPKDNTYT
                     TYHNNANKVNLGKLSEREANLLFAIFQRLKDQGNTLIRFEPQDLKRMIMVKSNLTNRQ
                     LLQVLKNLLDNISGANFWIIREHVENGEIYEDHTSYMLFKQFEIRIHKPTQTIEYLDV
                     QLNDSYQYLLNNLGMGGQYTSFKLLEFQRVRGKYAKTLYRLLKQYKSTGILSVEWTQF
                     RELLDIPKDYKMENIDQKVLNPSLKELRKIYPFEHLSYKKERKSHDKRKVTHIDFYFE
                     QLPEGENKKQKQADKQRAKRDIKLVAWDIKRQGMLKRSKETLEVREMDLKSLMGSLFE
                     NPNGVILKVENITKEKNKFFMHVSYPNRKNPPQKIPVSDKRYALELLYVSGGYTFKKD
                     NLLQEIETFTPSIHPITNEPIKEFAQYIGKTINITNFNVDQCPEGINNYLKITRIVKL
                     NDNRICVSVQDVDKPDKLLNPFIAKDEKHLKNWFKKYYR"
     misc_feature    complement(2938..3642)
                     /locus_tag="HPELS_08394"
                     /note="Initiator Replication protein; Region: Rep_3;
                     pfam01051"
                     /db_xref="CDD:216266"
     gene            complement(4551..4652)
                     /locus_tag="HPELS_08399"
                     /db_xref="GeneID:12020894"
     CDS             complement(4551..4652)
                     /locus_tag="HPELS_08399"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_005425741.1"
                     /db_xref="GI:383750639"
                     /db_xref="GeneID:12020894"
                     /translation="MDKSASQFESVGVGRSCFCVSKIKQDSANLALG"
     gene            complement(4804..5220)
                     /locus_tag="HPELS_08404"
                     /db_xref="GeneID:12020895"
     CDS             complement(4804..5220)
                     /locus_tag="HPELS_08404"
                     /note="COG1943 Transposase and inactivated derivatives"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200 insertion sequence from SARA17"
                     /protein_id="YP_005425742.1"
                     /db_xref="GI:383750640"
                     /db_xref="GeneID:12020895"
                     /translation="MKKIDDMRHGRHCVFLMHVHLVFVTKYRRSAFNKEVIDFLGSVF
                     AKVCKDFESELVEFDGESDHVYLLINYPPKVSVSKLVNSLKGVSSRLTRQHHFKSVEA
                     SLWGKHLWSPSYFAGSCGGAPLEMIKQYIQEQETPH"
     misc_feature    complement(4807..5205)
                     /locus_tag="HPELS_08404"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG1943"
                     /db_xref="CDD:224854"
ORIGIN      
        1 tatcccacta aagaacaaca agataaattg caacactgct tttttgtcta taaccaagct
       61 tataatattg gcttgaattt actgcaagag caatatgaaa ccaacaaaga tttacctccc
      121 aaagaaagaa agtggaaaag atcaagcgag ttagataaag cgattaaaca ccacttgaac
      181 gctagggggt taagctttag tagtgtgata gcccaacaat cacgcatgaa cgttgaaagg
      241 gctttaaaag atgcttttaa agttaaaaac aggggctttc ctaaattcaa aaactctaaa
      301 tccgccaaac aatctttttt gtggaacaat caaggcttct ctatcaaaga gagcgatgag
      361 gaacgcttca agacattcac tctgatgaaa atgcctttac tcatgcgcat gcatagagac
      421 ttccccccta attttaaagt gaaacaaatt agtatctctt gcagccatag aaaatatttt
      481 gttagcttta gcgtggaata cgaacaagac attactccca tcaaaaaccc taaagattgt
      541 gtggggctag atttgaatat ccttgatata gcttgttctt gtggcataaa caaccatgaa
      601 aaactaacgg attttaagca ataccaaaca gacatgaaag aattactagg gatagaaata
      661 gacaaagagt tggatactaa acgactcatc cctacttatt ccaaattgta ttctttaaaa
      721 aaatactcta aaaaatttaa aagattacaa agaaaacaaa gccgtagggt gttaaagtct
      781 aaacaaaaca aaaccaaatt aggaggtaat ttttacaaaa cccaaaagaa attaaaccaa
      841 gcctttgaca agtctagtca tcaaaaaaca gacagatacc ataaaatcac aagcgaactt
      901 tcaaagcaat ttgaattgat agtagttgaa gatttgcaag taaaaaacat gactaaaaga
      961 gctaaactca aaaatgttaa acaaaagagt gggcttaatc aatctatcaa caatacttca
     1021 ttctatcaaa tcatttcttt tttagattac aaacaacagc ataatggcaa attgttagtg
     1081 aaagttcccc cacaatatac gagtaaaact tgccattgtt gtgggaatat caaccacaag
     1141 cttaaattaa atcataggca atattggtgt ttagaatgcg ggtatagaga acacagagac
     1201 atcaacgctg cgaacaatat tttaagcaaa gggttaagtc tttttggggt aggaaatatc
     1261 catgcagact ttaaagaaca aagcctttcg tgttagcgtt caatagaatg ctttagttag
     1321 gaagctcctt gctttagcaa ggggtggttt cacatgtgct tttagatgct aaaccagtgg
     1381 gattggctaa atggctagcg actaaaaggg aaatgaagtt tttttgaagt caatcaggtt
     1441 gtttggattt tttagctgtt ttttgctatc taaaatcgcc tacaaccaac gaaaagcaaa
     1501 aaaccgacta atgactacct acaagctaaa aaacgcaaaa aacaaaagca cacaagcaaa
     1561 aataagcggt ttcactcaag aaaagaaata gctaaccatt tcattgaaat tgtcttgact
     1621 ttgcaaaatg gtgtctttca agtagccttt tgtgttgtca tattctttga tgcccctata
     1681 gtaaaaggct ttgtgttcgt tttctatgat gaaaggcatg atattatttt tcaaacattc
     1741 tttgaacatc actaatcgcc ccaccctacc attgccatca ctaaaagggt gtatcttttc
     1801 aaaagccaca tgaaaatcta tgatgttttc caaacttgtt gcagtcaggc tgtggtagcg
     1861 ttgcaaaaga tttgtcaatt cgctttcaac taatttgggt cttgttgtag cgctattgcc
     1921 tacaaaatta gggcgttttt tgaaaccacc aataacttca tcagaacaat tctttttcaa
     1981 gattttgtgt aaagtcttga agtattctaa actcaaaggt tttttgtagt tttcaagcaa
     2041 gtaattcacg cattcaaaat gattgatagt ttcaaaaata tcatcaagtt tgatattggc
     2101 gtttttttca gttatgagaa cggatttgtc aaaaatatga gcggtttgtt cataggtcaa
     2161 accgcttccc tcaatacgat tagagttgta agaaaatttg atttggatca agtggtaaat
     2221 gccatttttg atagcattct ttctttcgtg attcagtttt tctatgagtt tagtcagcat
     2281 gcatctgtct tttcacctgt agtatttctt aaaccaattc ttcaaatgtt tttcatcttt
     2341 agcgatgaaa gggtttagga gtttgtcagg tttatccaca tcttggactg aaacacagat
     2401 ccgattgtca ttcaatttca caatcctagt gattttcagg taattgttga ttccctcagg
     2461 gcattgatcc acattgaagt tggtgatgtt aatcgttttg ccaatgtatt gtgcaaattc
     2521 cttgataggt tcattcgtga tagggtggat gctaggcgta aaggtttcaa tctcttgcaa
     2581 caaattgtct tttttaaaag tgtagcctcc actgacatac aaaagttcta aagcatatcg
     2641 tttgtcagat acagggattt tttgtggggg gttttttcgg ttagggtaag aaacatgcat
     2701 gaagaatttg tttttttctt tagtgatgtt ttcaactttt aaaataaccc cattagggtt
     2761 ttcaaaaaga gatcccatca aacttttcaa atccatttcc ctaacttcta gggtttcttt
     2821 agagcgtttt aacatgcctt gtcttttaat atcccacgct acgagcttga tgtctctttt
     2881 agcgcgttgc ttgtcagctt gtttttgttt cttattttcg ccttcaggca attgctcaaa
     2941 gtagaaatca atgtgcgtta ctttacgctt gtcatggctt ttgcgttctt ttttgtagct
     3001 caagtgttca aaagggtaga tttttctgag ttctttgaga cttggattta agactttttg
     3061 atcgatgttt tccattttgt agtcttttgg aatgtctaaa agctctctga attgagtcca
     3121 ttccacgctc aaaatccctg tgcttttgta ttgcttgagc aagcggtaaa gcgttttagc
     3181 gtatttgcct ctcactcttt ggaattctaa aagtttgaaa gaagtgtatt gaccgcccat
     3241 tcctagattg ttgagcaagt attgatagct atcattgagt tggacatcta agtattctat
     3301 agtttgggtt ggcttatgga tgcggatttc aaattgtttg aaaagcatgt agctagtgtg
     3361 atcttcatag atttcgccat tttcaacatg ctctctaatg atccaaaaat tagcaccact
     3421 tatgttgtca agcaaatttt ttaagacttg caataattgc ctgttggtta agttagattt
     3481 gaccataatc atgcgtttta aatcttgcgg ttcaaaacga atgagggtat tcccttgatc
     3541 tttaagcctt tgaaaaatag cgaataaaag attggcttcc ctttcgctca atttccctag
     3601 attgacctta ttagcgttat tgtggtaggt ggtataggtg ttatctttag gggtgctaac
     3661 cactaaatct ttgcatggtg tgggggtggt ttgtggctct tttgttggtg tgggtttttc
     3721 tttttcaaac tcatttggta atttttctgt aatttcttta aatttttgat taaaaccgct
     3781 caaaatactt ggagtgattt tgtctatgta agtttgtatc ttttgttttt gtagtttaat
     3841 ttgtggggtt tgtgggagcg tgtctaattc ttctaataat tttcgtaatt ccaattcttg
     3901 ttttctaagc tgtttaaaat tcgtattcat gggcatttga gtgcctttta atgcttattt
     3961 ttcaaaagac gatataataa caggagtgaa acccttaaaa agtcttggcg gacttataag
     4021 ggttattaaa acgctaaggt tttaatatag tggctgtgtt aagattacca ctaaaatcac
     4081 tactatcaaa aatgctttca tggtgtgcct cctaacggag tgccacccgc tacaaactcc
     4141 taacccacta gcttttaaag ctaatttctc caaatttgtt aacactagga ttagcaacca
     4201 tgtcataccg ccttaggtta ttattttagc taaaaattgt taataatcat aactttaaaa
     4261 taaagaagtt ctgttatcac tcgtaagaag ttctgttatc actcgtaaga agttctgtta
     4321 tcactcgtaa gaagttctgt tatcactcgt aagaagttct gttttattca ttttcacacc
     4381 aaaaatgaga aaccctacag cttcgttatt tagggggttg caacccccaa tccctcacgc
     4441 gcgcgcatgc gagtaaaaca tgtaaaaaac agcatgctat ttaaaacatg taataaaaac
     4501 aacgcgcatg acgcgctaca tattttggag ttttagtttt taggggtttt ttagcctaat
     4561 gccaggtttg cgctatcttg tttgattttg ctaacgcaaa aacagcttcg gccaacgcct
     4621 acgctttcaa actgcgatgc gcttttgtcc atgctcgcta acgcttcgct tatcccacta
     4681 gcgcgaaaaa ctccgtcctt tagggcggag atgtaagtgc ttagacatca ggctatttga
     4741 atatcgtttc acctagatcc attcgctttt tagcgcattc tattaaaaat caaagttagc
     4801 tagttaatgc ggtgtttctt gttcttgtat gtattgctta atcatctcta aaggtgcacc
     4861 cccacaactc ccagcgaaat aactaggcga ccataaatgc ttcccccaca aactagcttc
     4921 aacgcttttg aaatggtgtt gtctagtcaa acgactgcta acgcctttta aagaattaac
     4981 taacttactc acgctcactt ttggagggta gttgataagc aaatacacat gatcgctctc
     5041 cccatcaaat tctaccaatt cgctctcaaa gtccttacac actttggcaa acaccgatcc
     5101 taaaaaatct atcacttcct tgttgaacgc tgaacgcctg tatttagtaa caaataccaa
     5161 atgcacatgc attaaaaaaa cacaatgtct tccgtgtctc atatcatcaa tttttttcat
     5221 agacctattt taacaaaaag aggttaaaat acttctatga aagtcaataa gggttttaaa
     5281 ttccgcttg
//
