Msp_0003 PWY-5686 UMP biosynthesis
Msp_0004 PWY-6829 tRNA methylation (yeast)
Msp_0011 PWY-7206 pyrimidine deoxyribonucleotides dephosphorylation
Msp_0012 PWY-5508 adenosylcobalamin biosynthesis from cobyrinate a,c-diamide II
Msp_0012 PWY-5509 adenosylcobalamin biosynthesis from cobyrinate a,c-diamide I
Msp_0012 PWY-6269 adenosylcobalamin salvage from cobinamide II
Msp_0015 PWY-5057 L-valine degradation II
Msp_0015 PWY-5076 L-leucine degradation III
Msp_0015 PWY-5078 L-isoleucine degradation II
Msp_0015 PWY-5101 L-isoleucine biosynthesis II
Msp_0015 PWY-5103 L-isoleucine biosynthesis III
Msp_0015 PWY-5104 L-isoleucine biosynthesis IV
Msp_0015 PWY-5108 L-isoleucine biosynthesis V
Msp_0020 PWY-5381 pyridine nucleotide cycling (plants)
Msp_0020 PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation
Msp_0020 PWY-6596 adenosine nucleotides degradation I
Msp_0020 PWY-6606 guanosine nucleotides degradation II
Msp_0020 PWY-6607 guanosine nucleotides degradation I
Msp_0020 PWY-6608 guanosine nucleotides degradation III
Msp_0020 PWY-7185 UTP and CTP dephosphorylation I
Msp_0022 PWY-5101 L-isoleucine biosynthesis II
Msp_0022 PWY-5103 L-isoleucine biosynthesis III
Msp_0022 PWY-5104 L-isoleucine biosynthesis IV
Msp_0022 PWY-7111 pyruvate fermentation to isobutanol (engineered)
Msp_0025 PWY-5101 L-isoleucine biosynthesis II
Msp_0025 PWY-5103 L-isoleucine biosynthesis III
Msp_0025 PWY-5104 L-isoleucine biosynthesis IV
Msp_0025 PWY-5938 (R)-acetoin biosynthesis I
Msp_0025 PWY-5939 (R)-acetoin biosynthesis II
Msp_0025 PWY-6389 (S)-acetoin biosynthesis
Msp_0025 PWY-7111 pyruvate fermentation to isobutanol (engineered)
Msp_0026 PWY-5101 L-isoleucine biosynthesis II
Msp_0026 PWY-5103 L-isoleucine biosynthesis III
Msp_0026 PWY-5104 L-isoleucine biosynthesis IV
Msp_0026 PWY-5938 (R)-acetoin biosynthesis I
Msp_0026 PWY-5939 (R)-acetoin biosynthesis II
Msp_0026 PWY-6389 (S)-acetoin biosynthesis
Msp_0026 PWY-7111 pyruvate fermentation to isobutanol (engineered)
Msp_0028 PWY-5101 L-isoleucine biosynthesis II
Msp_0028 PWY-5103 L-isoleucine biosynthesis III
Msp_0028 PWY-5104 L-isoleucine biosynthesis IV
Msp_0028 PWY-5938 (R)-acetoin biosynthesis I
Msp_0028 PWY-5939 (R)-acetoin biosynthesis II
Msp_0028 PWY-6389 (S)-acetoin biosynthesis
Msp_0028 PWY-7111 pyruvate fermentation to isobutanol (engineered)
Msp_0029 PWY-5101 L-isoleucine biosynthesis II
Msp_0029 PWY-5103 L-isoleucine biosynthesis III
Msp_0029 PWY-5104 L-isoleucine biosynthesis IV
Msp_0029 PWY-5938 (R)-acetoin biosynthesis I
Msp_0029 PWY-5939 (R)-acetoin biosynthesis II
Msp_0029 PWY-6389 (S)-acetoin biosynthesis
Msp_0029 PWY-7111 pyruvate fermentation to isobutanol (engineered)
Msp_0030 PWY-6121 5-aminoimidazole ribonucleotide biosynthesis I
Msp_0030 PWY-6122 5-aminoimidazole ribonucleotide biosynthesis II
Msp_0030 PWY-6277 superpathway of 5-aminoimidazole ribonucleotide biosynthesis
Msp_0031 PWY-4981 L-proline biosynthesis II (from arginine)
Msp_0031 PWY-4984 urea cycle
Msp_0031 PWY-7400 L-arginine biosynthesis IV (archaebacteria)
Msp_0065 PWY-6397 mycolyl-arabinogalactan-peptidoglycan complex biosynthesis
Msp_0065 PWY-7328 superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis
Msp_0080 PWY-5265 peptidoglycan biosynthesis II (staphylococci)
Msp_0080 PWY-6470 peptidoglycan biosynthesis V (β-lactam resistance)
Msp_0080 PWY-6471 peptidoglycan biosynthesis IV (Enterococcus faecium)
Msp_0087 PWY-7377 cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)
Msp_0090 PWY-6160 3-dehydroquinate biosynthesis II (archaea)
Msp_0091 PWY-6160 3-dehydroquinate biosynthesis II (archaea)
Msp_0102 PWY-7377 cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)
Msp_0104 PWY-3821 galactose degradation III
Msp_0104 PWY-6163 chorismate biosynthesis from 3-dehydroquinate
Msp_0104 PWY-6317 galactose degradation I (Leloir pathway)
Msp_0104 PWY-6527 stachyose degradation
Msp_0105 PWY-3461 L-tyrosine biosynthesis II
Msp_0105 PWY-3462 L-phenylalanine biosynthesis II
Msp_0105 PWY-6120 L-tyrosine biosynthesis III
Msp_0105 PWY-6627 salinosporamide A biosynthesis
Msp_0107 PWY-2941 L-lysine biosynthesis II
Msp_0107 PWY-2942 L-lysine biosynthesis III
Msp_0107 PWY-5097 L-lysine biosynthesis VI
Msp_0107 PWY-6559 spermidine biosynthesis II
Msp_0107 PWY-6562 norspermidine biosynthesis
Msp_0107 PWY-7153 grixazone biosynthesis
Msp_0108 PWY-2941 L-lysine biosynthesis II
Msp_0108 PWY-2942 L-lysine biosynthesis III
Msp_0108 PWY-5097 L-lysine biosynthesis VI
Msp_0109 PWY-2941 L-lysine biosynthesis II
Msp_0109 PWY-2942 L-lysine biosynthesis III
Msp_0109 PWY-5097 L-lysine biosynthesis VI
Msp_0110 PWY-2941 L-lysine biosynthesis II
Msp_0110 PWY-2942 L-lysine biosynthesis III
Msp_0110 PWY-5097 L-lysine biosynthesis VI
Msp_0110 PWY-5154 L-arginine biosynthesis III (via N-acetyl-L-citrulline)
Msp_0110 PWY-6559 spermidine biosynthesis II
Msp_0110 PWY-6562 norspermidine biosynthesis
Msp_0110 PWY-7153 grixazone biosynthesis
Msp_0110 PWY-7400 L-arginine biosynthesis IV (archaebacteria)
Msp_0112 PWY-5531 chlorophyllide a biosynthesis II (anaerobic)
Msp_0112 PWY-7159 chlorophyllide a biosynthesis III (aerobic, light independent)
Msp_0117 PWY-4381 fatty acid biosynthesis initiation I
Msp_0163 PWY-5198 factor 420 biosynthesis
Msp_0175 PWY-6167 flavin biosynthesis II (archaea)
Msp_0175 PWY-6168 flavin biosynthesis III (fungi)
Msp_0177 PWY-6167 flavin biosynthesis II (archaea)
Msp_0181 PWY-5921 glutaminyl-tRNAgln biosynthesis via transamidation
Msp_0182 PWY-5531 chlorophyllide a biosynthesis II (anaerobic)
Msp_0182 PWY-7159 chlorophyllide a biosynthesis III (aerobic, light independent)
Msp_0199 PWY-6871 3-methylbutanol biosynthesis
Msp_0208 PWY-6655 xanthan biosynthesis
Msp_0208 PWY-6658 acetan biosynthesis
Msp_0210 PWY-7346 UDP-α-D-glucuronate biosynthesis (from UDP-glucose)
Msp_0217 PWY-7335 UDP-N-acetyl-α-D-mannosaminouronate biosynthesis
Msp_0223 PWY-6397 mycolyl-arabinogalactan-peptidoglycan complex biosynthesis
Msp_0223 PWY-7328 superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis
Msp_0228 PWY-6890 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis
Msp_0234 PWY-381 nitrate reduction II (assimilatory)
Msp_0234 PWY-5675 nitrate reduction V (assimilatory)
Msp_0234 PWY-6549 L-glutamine biosynthesis III
Msp_0234 PWY-6963 ammonia assimilation cycle I
Msp_0234 PWY-6964 ammonia assimilation cycle II
Msp_0240 PWY-7234 inosine-5'-phosphate biosynthesis III
Msp_0243 PWY-5209 methyl-coenzyme M oxidation to CO2
Msp_0245 PWY-5209 methyl-coenzyme M oxidation to CO2
Msp_0249 PWY-5188 tetrapyrrole biosynthesis I (from glutamate)
Msp_0251 PWY-6890 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis
Msp_0254 PWY-7187 pyrimidine deoxyribonucleotides de novo biosynthesis II
Msp_0254 PWY-7220 adenosine deoxyribonucleotides de novo biosynthesis II
Msp_0254 PWY-7222 guanosine deoxyribonucleotides de novo biosynthesis II
Msp_0263 PWY-6749 CMP-legionaminate biosynthesis I
Msp_0278 PWY-6637 sulfolactate degradation II
Msp_0278 PWY-6643 coenzyme M biosynthesis II
Msp_0280 PWY-6121 5-aminoimidazole ribonucleotide biosynthesis I
Msp_0280 PWY-6122 5-aminoimidazole ribonucleotide biosynthesis II
Msp_0280 PWY-6277 superpathway of 5-aminoimidazole ribonucleotide biosynthesis
Msp_0291 PWY-6829 tRNA methylation (yeast)
Msp_0294 PWY-5663 tetrahydrobiopterin biosynthesis I
Msp_0294 PWY-5664 tetrahydrobiopterin biosynthesis II
Msp_0294 PWY-6147 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I
Msp_0294 PWY-6703 preQ0 biosynthesis
Msp_0294 PWY-6797 6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (archaea)
Msp_0294 PWY-6983 tetrahydrobiopterin biosynthesis III
Msp_0294 PWY-7442 drosopterin and aurodrosopterin biosynthesis
Msp_0296 PWY-5198 factor 420 biosynthesis
Msp_0297 PWY-6829 tRNA methylation (yeast)
Msp_0297 PWY-7285 methylwyosine biosynthesis
Msp_0297 PWY-7286 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis
Msp_0323 PWY-5686 UMP biosynthesis
Msp_0328 PWY-5484 glycolysis II (from fructose 6-phosphate)
Msp_0329 PWY-3581 (S)-reticuline biosynthesis I
Msp_0329 PWY-5254 methanofuran biosynthesis
Msp_0329 PWY-5474 hydroxycinnamic acid tyramine amides biosynthesis
Msp_0329 PWY-6133 (S)-reticuline biosynthesis II
Msp_0329 PWY-6802 salidroside biosynthesis
Msp_0329 PWY-7297 octopamine biosynthesis
Msp_0357 PWY-6545 pyrimidine deoxyribonucleotides de novo biosynthesis III
Msp_0357 PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I
Msp_0357 PWY-7187 pyrimidine deoxyribonucleotides de novo biosynthesis II
Msp_0357 PWY-7197 pyrimidine deoxyribonucleotide phosphorylation
Msp_0357 PWY-7198 pyrimidine deoxyribonucleotides de novo biosynthesis IV
Msp_0357 PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP
Msp_0373 PWY-6148 tetrahydromethanopterin biosynthesis
Msp_0390 PWY-6167 flavin biosynthesis II (archaea)
Msp_0390 PWY-6168 flavin biosynthesis III (fungi)
Msp_0392 PWY-5198 factor 420 biosynthesis
Msp_0397 PWY-5686 UMP biosynthesis
Msp_0410 PWY-5316 nicotine biosynthesis
Msp_0410 PWY-5381 pyridine nucleotide cycling (plants)
Msp_0410 PWY-5653 NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde
Msp_0410 PWY-7342 superpathway of nicotine biosynthesis
Msp_0415 PWY-40 putrescine biosynthesis I
Msp_0415 PWY-6305 putrescine biosynthesis IV
Msp_0416 PWY-5188 tetrapyrrole biosynthesis I (from glutamate)
Msp_0416 PWY-5189 tetrapyrrole biosynthesis II (from glycine)
Msp_0428 PWY-5796 malonate decarboxylase activation
Msp_0431 PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation
Msp_0431 PWY-6596 adenosine nucleotides degradation I
Msp_0431 PWY-7221 guanosine ribonucleotides de novo biosynthesis
Msp_0449 PWY-6936 seleno-amino acid biosynthesis
Msp_0450 PWY-6936 seleno-amino acid biosynthesis
Msp_0450 PWY-7274 D-cycloserine biosynthesis
Msp_0453 PWY-7176 UTP and CTP de novo biosynthesis
Msp_0453 PWY-7177 UTP and CTP dephosphorylation II
Msp_0453 PWY-7185 UTP and CTP dephosphorylation I
Msp_0485 PWY-1042 glycolysis IV (plant cytosol)
Msp_0485 PWY-2221 Entner-Doudoroff pathway III (semi-phosphorylative)
Msp_0485 PWY-5484 glycolysis II (from fructose 6-phosphate)
Msp_0485 PWY-5723 Rubisco shunt
Msp_0485 PWY-6142 gluconeogenesis II (Methanobacterium thermoautotrophicum)
Msp_0485 PWY-6886 1-butanol autotrophic biosynthesis
Msp_0485 PWY-6901 superpathway of glucose and xylose degradation
Msp_0485 PWY-7003 glycerol degradation to butanol
Msp_0485 PWY-7124 ethylene biosynthesis V (engineered)
Msp_0485 PWY-7218 photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
Msp_0498 PWY-6163 chorismate biosynthesis from 3-dehydroquinate
Msp_0520 PWY-6700 queuosine biosynthesis
Msp_0520 PWY-6711 archaeosine biosynthesis
Msp_0528 PWY-6840 homoglutathione biosynthesis
Msp_0528 PWY-7255 ergothioneine biosynthesis I (bacteria)
Msp_0531 PWY-5833 CDP-4-dehydro-3,6-dideoxy-D-glucose biosynthesis
Msp_0531 PWY-5940 streptomycin biosynthesis
Msp_0532 PWY-5833 CDP-4-dehydro-3,6-dideoxy-D-glucose biosynthesis
Msp_0549 PWY-5154 L-arginine biosynthesis III (via N-acetyl-L-citrulline)
Msp_0550 PWY-5154 L-arginine biosynthesis III (via N-acetyl-L-citrulline)
Msp_0550 PWY-7400 L-arginine biosynthesis IV (archaebacteria)
Msp_0552 PWY-5154 L-arginine biosynthesis III (via N-acetyl-L-citrulline)
Msp_0552 PWY-7400 L-arginine biosynthesis IV (archaebacteria)
Msp_0563 PWY-6482 diphthamide biosynthesis (archaea)
Msp_0563 PWY-7546 diphthamide biosynthesis (eukaryotes)
Msp_0577 PWY-6163 chorismate biosynthesis from 3-dehydroquinate
Msp_0577 PWY-6416 quinate degradation II
Msp_0577 PWY-6707 gallate biosynthesis
Msp_0579 PWY-6163 chorismate biosynthesis from 3-dehydroquinate
Msp_0583 PWY-5392 reductive TCA cycle II
Msp_0583 PWY-5537 pyruvate fermentation to acetate V
Msp_0583 PWY-5538 pyruvate fermentation to acetate VI
Msp_0583 PWY-5690 TCA cycle II (plants and fungi)
Msp_0583 PWY-5913 TCA cycle VI (obligate autotrophs)
Msp_0583 PWY-6728 methylaspartate cycle
Msp_0583 PWY-6969 TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)
Msp_0583 PWY-7384 anaerobic energy metabolism (invertebrates, mitochondrial)
Msp_0584 PWY-6174 mevalonate pathway II (archaea)
Msp_0584 PWY-7391 isoprene biosynthesis II (engineered)
Msp_0584 PWY-7524 mevalonate pathway III (archaea)
Msp_0584 PWY-922 mevalonate pathway I
Msp_0589 PWY-7219 adenosine ribonucleotides de novo biosynthesis
Msp_0591 PWY-241 C4 photosynthetic carbon assimilation cycle, NADP-ME type
Msp_0591 PWY-6142 gluconeogenesis II (Methanobacterium thermoautotrophicum)
Msp_0591 PWY-7115 C4 photosynthetic carbon assimilation cycle, NAD-ME type
Msp_0591 PWY-7117 C4 photosynthetic carbon assimilation cycle, PEPCK type
Msp_0618 PWY-4983 L-citrulline-nitric oxide cycle
Msp_0618 PWY-4984 urea cycle
Msp_0618 PWY-5 canavanine biosynthesis
Msp_0618 PWY-5154 L-arginine biosynthesis III (via N-acetyl-L-citrulline)
Msp_0618 PWY-7400 L-arginine biosynthesis IV (archaebacteria)
Msp_0630 PWY-6545 pyrimidine deoxyribonucleotides de novo biosynthesis III
Msp_0630 PWY-7176 UTP and CTP de novo biosynthesis
Msp_0630 PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I
Msp_0630 PWY-7187 pyrimidine deoxyribonucleotides de novo biosynthesis II
Msp_0630 PWY-7197 pyrimidine deoxyribonucleotide phosphorylation
Msp_0630 PWY-7198 pyrimidine deoxyribonucleotides de novo biosynthesis IV
Msp_0630 PWY-7205 CMP phosphorylation
Msp_0630 PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP
Msp_0630 PWY-7220 adenosine deoxyribonucleotides de novo biosynthesis II
Msp_0630 PWY-7221 guanosine ribonucleotides de novo biosynthesis
Msp_0630 PWY-7222 guanosine deoxyribonucleotides de novo biosynthesis II
Msp_0630 PWY-7224 purine deoxyribonucleosides salvage
Msp_0630 PWY-7226 guanosine deoxyribonucleotides de novo biosynthesis I
Msp_0630 PWY-7227 adenosine deoxyribonucleotides de novo biosynthesis
Msp_0634 PWY-6349 CDP-archaeol biosynthesis
Msp_0643 PWY-5316 nicotine biosynthesis
Msp_0643 PWY-7342 superpathway of nicotine biosynthesis
Msp_0647 PWY-6163 chorismate biosynthesis from 3-dehydroquinate
Msp_0652 PWY-6689 tRNA splicing
Msp_0661 PWY-6147 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I
Msp_0661 PWY-6148 tetrahydromethanopterin biosynthesis
Msp_0661 PWY-6797 6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (archaea)
Msp_0661 PWY-6898 thiamin salvage III
Msp_0661 PWY-6907 thiamin diphosphate biosynthesis III (Staphylococcus)
Msp_0661 PWY-6908 thiamin diphosphate biosynthesis IV (eukaryotes)
Msp_0661 PWY-7539 6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia)
Msp_0662 PWY-6832 2-aminoethylphosphonate degradation II
Msp_0672 PWY-1622 formaldehyde assimilation I (serine pathway)
Msp_0672 PWY-5392 reductive TCA cycle II
Msp_0672 PWY-561 superpathway of glyoxylate cycle and fatty acid degradation
Msp_0672 PWY-5690 TCA cycle II (plants and fungi)
Msp_0672 PWY-5913 TCA cycle VI (obligate autotrophs)
Msp_0672 PWY-6728 methylaspartate cycle
Msp_0672 PWY-6969 TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)
Msp_0672 PWY-7115 C4 photosynthetic carbon assimilation cycle, NAD-ME type
Msp_0672 PWY-7383 anaerobic energy metabolism (invertebrates, cytosol)
Msp_0676 PWY-5344 L-homocysteine biosynthesis
Msp_0677 PWY-5344 L-homocysteine biosynthesis
Msp_0677 PWY-7174 S-methyl-5-thio-α-D-ribose 1-phosphate degradation II
Msp_0682 PWY-6897 thiamin salvage II
Msp_0682 PWY-7353 4-methyl-5(β-hydroxyethyl)thiazole salvage (yeast)
Msp_0682 PWY-7357 thiamin formation from pyrithiamine and oxythiamine (yeast)
Msp_0683 PWY-6893 thiamin diphosphate biosynthesis II (Bacillus)
Msp_0683 PWY-6894 thiamin diphosphate biosynthesis I (E. coli)
Msp_0683 PWY-6897 thiamin salvage II
Msp_0683 PWY-6907 thiamin diphosphate biosynthesis III (Staphylococcus)
Msp_0683 PWY-6908 thiamin diphosphate biosynthesis IV (eukaryotes)
Msp_0683 PWY-7353 4-methyl-5(β-hydroxyethyl)thiazole salvage (yeast)
Msp_0683 PWY-7357 thiamin formation from pyrithiamine and oxythiamine (yeast)
Msp_0694 PWY-6897 thiamin salvage II
Msp_0694 PWY-7353 4-methyl-5(β-hydroxyethyl)thiazole salvage (yeast)
Msp_0694 PWY-7357 thiamin formation from pyrithiamine and oxythiamine (yeast)
Msp_0703 PWY-6683 sulfate reduction III (assimilatory)
Msp_0718 PWY-1361 benzoyl-CoA degradation I (aerobic)
Msp_0718 PWY-5109 2-methylbutanoate biosynthesis
Msp_0718 PWY-5136 fatty acid β-oxidation II (peroxisome)
Msp_0718 PWY-5138 unsaturated, even numbered fatty acid β-oxidation
Msp_0718 PWY-5177 glutaryl-CoA degradation
Msp_0718 PWY-5789 3-hydroxypropanoate/4-hydroxybutanate cycle
Msp_0718 PWY-6435 4-hydroxybenzoate biosynthesis V
Msp_0718 PWY-6583 pyruvate fermentation to butanol I
Msp_0718 PWY-6863 pyruvate fermentation to hexanol
Msp_0718 PWY-6883 pyruvate fermentation to butanol II
Msp_0718 PWY-6944 androstenedione degradation
Msp_0718 PWY-6945 cholesterol degradation to androstenedione I (cholesterol oxidase)
Msp_0718 PWY-6946 cholesterol degradation to androstenedione II (cholesterol dehydrogenase)
Msp_0718 PWY-7007 methyl ketone biosynthesis
Msp_0718 PWY-7046 4-coumarate degradation (anaerobic)
Msp_0718 PWY-7094 fatty acid salvage
Msp_0718 PWY-7216 (R)- and (S)-3-hydroxybutanoate biosynthesis
Msp_0718 PWY-735 jasmonic acid biosynthesis
Msp_0718 PWY-7401 crotonate fermentation (to acetate and cyclohexane carboxylate)
Msp_0761 PWY-5531 chlorophyllide a biosynthesis II (anaerobic)
Msp_0761 PWY-7159 chlorophyllide a biosynthesis III (aerobic, light independent)
Msp_0764 PWY-5381 pyridine nucleotide cycling (plants)
Msp_0770 PWY-7204 pyridoxal 5'-phosphate salvage II (plants)
Msp_0770 PWY-7282 4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis (yeast)
Msp_0774 PWY-5531 chlorophyllide a biosynthesis II (anaerobic)
Msp_0774 PWY-7159 chlorophyllide a biosynthesis III (aerobic, light independent)
Msp_0796 PWY-6281 L-selenocysteine biosynthesis II (archaea and eukaryotes)
Msp_0856 PWY-5123 trans, trans-farnesyl diphosphate biosynthesis
Msp_0856 PWY-6174 mevalonate pathway II (archaea)
Msp_0856 PWY-6383 mono-trans, poly-cis decaprenyl phosphate biosynthesis
Msp_0856 PWY-6859 all-trans-farnesol biosynthesis
Msp_0856 PWY-7102 bisabolene biosynthesis
Msp_0856 PWY-7391 isoprene biosynthesis II (engineered)
Msp_0856 PWY-7524 mevalonate pathway III (archaea)
Msp_0856 PWY-7560 methylerythritol phosphate pathway II
Msp_0856 PWY-922 mevalonate pathway I
Msp_0857 PWY-6174 mevalonate pathway II (archaea)
Msp_0857 PWY-7524 mevalonate pathway III (archaea)
Msp_0858 PWY-3821 galactose degradation III
Msp_0858 PWY-6174 mevalonate pathway II (archaea)
Msp_0858 PWY-6317 galactose degradation I (Leloir pathway)
Msp_0858 PWY-6527 stachyose degradation
Msp_0858 PWY-7391 isoprene biosynthesis II (engineered)
Msp_0858 PWY-922 mevalonate pathway I
Msp_0862 PWY-1042 glycolysis IV (plant cytosol)
Msp_0862 PWY-1622 formaldehyde assimilation I (serine pathway)
Msp_0862 PWY-2221 Entner-Doudoroff pathway III (semi-phosphorylative)
Msp_0862 PWY-5484 glycolysis II (from fructose 6-phosphate)
Msp_0862 PWY-5723 Rubisco shunt
Msp_0862 PWY-6142 gluconeogenesis II (Methanobacterium thermoautotrophicum)
Msp_0862 PWY-6886 1-butanol autotrophic biosynthesis
Msp_0862 PWY-6901 superpathway of glucose and xylose degradation
Msp_0862 PWY-7003 glycerol degradation to butanol
Msp_0862 PWY-7124 ethylene biosynthesis V (engineered)
Msp_0862 PWY-7218 photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
Msp_0874 PWY-6349 CDP-archaeol biosynthesis
Msp_0878 PWY-5381 pyridine nucleotide cycling (plants)
Msp_0881 PWY-7205 CMP phosphorylation
Msp_0884 PWY-7219 adenosine ribonucleotides de novo biosynthesis
Msp_0915 PWY-6987 lipoate biosynthesis and incorporation III (Bacillus)
Msp_0915 PWY-7381 lipoate biosynthesis and incorporation (glycine cleavage system, yeast)
Msp_0919 PWY-5392 reductive TCA cycle II
Msp_0919 PWY-5483 pyruvate fermentation to acetate III
Msp_0919 PWY-5535 acetate formation from acetyl-CoA II
Msp_0919 PWY-5537 pyruvate fermentation to acetate V
Msp_0919 PWY-5538 pyruvate fermentation to acetate VI
Msp_0919 PWY-5690 TCA cycle II (plants and fungi)
Msp_0919 PWY-5913 TCA cycle VI (obligate autotrophs)
Msp_0919 PWY-6728 methylaspartate cycle
Msp_0919 PWY-6969 TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)
Msp_0919 PWY-7384 anaerobic energy metabolism (invertebrates, mitochondrial)
Msp_0923 PWY-5188 tetrapyrrole biosynthesis I (from glutamate)
Msp_0924 PWY-5097 L-lysine biosynthesis VI
Msp_0966 PWY-6654 phosphopantothenate biosynthesis III
Msp_0986 PWY-7219 adenosine ribonucleotides de novo biosynthesis
Msp_0988 PWY-5194 siroheme biosynthesis
Msp_0988 PWY-7377 cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)
Msp_0995 PWY-1861 formaldehyde assimilation II (RuMP Cycle)
Msp_0995 PWY-5723 Rubisco shunt
Msp_0997 PWY-6349 CDP-archaeol biosynthesis
Msp_1002 PWY-6823 molybdenum cofactor biosynthesis
Msp_1002 PWY-6891 thiazole biosynthesis II (Bacillus)
Msp_1002 PWY-6892 thiazole biosynthesis I (E. coli)
Msp_1002 PWY-7250 [2Fe-2S] iron-sulfur cluster biosynthesis
Msp_1006 PWY-5198 factor 420 biosynthesis
Msp_1007 PWY-6910 hydroxymethylpyrimidine salvage
Msp_1007 PWY-7356 thiamin salvage IV (yeast)
Msp_1007 PWY-7357 thiamin formation from pyrithiamine and oxythiamine (yeast)
Msp_1009 PWY-1341 phenylacetate degradation II (anaerobic)
Msp_1009 PWY-6318 L-phenylalanine degradation IV (mammalian, via side chain)
Msp_1013 PWY-5207 coenzyme B/coenzyme M regeneration
Msp_1014 PWY-5207 coenzyme B/coenzyme M regeneration
Msp_1015 PWY-6700 queuosine biosynthesis
Msp_1017 PWY-6482 diphthamide biosynthesis (archaea)
Msp_1022 PWY-6829 tRNA methylation (yeast)
Msp_1022 PWY-7285 methylwyosine biosynthesis
Msp_1022 PWY-7286 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis
Msp_1023 PWY-4361 S-methyl-5-thio-α-D-ribose 1-phosphate degradation
Msp_1023 PWY-7174 S-methyl-5-thio-α-D-ribose 1-phosphate degradation II
Msp_1024 PWY-6823 molybdenum cofactor biosynthesis
Msp_1036 PWY-5686 UMP biosynthesis
Msp_1040 PWY-1341 phenylacetate degradation II (anaerobic)
Msp_1040 PWY-6318 L-phenylalanine degradation IV (mammalian, via side chain)
Msp_1044 PWY-3781 aerobic respiration I (cytochrome c)
Msp_1044 PWY-4302 aerobic respiration III (alternative oxidase pathway)
Msp_1044 PWY-561 superpathway of glyoxylate cycle and fatty acid degradation
Msp_1044 PWY-5690 TCA cycle II (plants and fungi)
Msp_1044 PWY-6728 methylaspartate cycle
Msp_1044 PWY-6969 TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)
Msp_1044 PWY-7254 TCA cycle VII (acetate-producers)
Msp_1044 PWY-7279 aerobic respiration II (cytochrome c) (yeast)
Msp_1048 PWY-7187 pyrimidine deoxyribonucleotides de novo biosynthesis II
Msp_1062 PWY-6349 CDP-archaeol biosynthesis
Msp_1063 PWY-6711 archaeosine biosynthesis
Msp_1070 PWY-5958 acridone alkaloid biosynthesis
Msp_1070 PWY-6660 2-heptyl-3-hydroxy-4(1H)-quinolone biosynthesis
Msp_1070 PWY-6661 4-hydroxy-2(1H)-quinolone biosynthesis
Msp_1071 PWY-5958 acridone alkaloid biosynthesis
Msp_1071 PWY-6660 2-heptyl-3-hydroxy-4(1H)-quinolone biosynthesis
Msp_1071 PWY-6661 4-hydroxy-2(1H)-quinolone biosynthesis
Msp_1083 PWY-7303 3-dimethylallyl-4-hydroxybenzoate biosynthesis
Msp_1085 PWY-5041 S-adenosyl-L-methionine cycle II
Msp_1088 PWY-3821 galactose degradation III
Msp_1088 PWY-6317 galactose degradation I (Leloir pathway)
Msp_1088 PWY-6397 mycolyl-arabinogalactan-peptidoglycan complex biosynthesis
Msp_1088 PWY-6527 stachyose degradation
Msp_1088 PWY-7328 superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis
Msp_1088 PWY-7344 UDP-D-galactose biosynthesis
Msp_1099 PWY-6871 3-methylbutanol biosynthesis
Msp_1101 PWY-3801 sucrose degradation II (sucrose synthase)
Msp_1101 PWY-6527 stachyose degradation
Msp_1101 PWY-6981 chitin biosynthesis
Msp_1101 PWY-7238 sucrose biosynthesis II
Msp_1101 PWY-7343 UDP-glucose biosynthesis
Msp_1114 PWY-3221 dTDP-L-rhamnose biosynthesis II
Msp_1114 PWY-6808 dTDP-D-forosamine biosynthesis
Msp_1114 PWY-6942 dTDP-D-desosamine biosynthesis
Msp_1114 PWY-6953 dTDP-3-acetamido-3,6-dideoxy-α-D-galactose biosynthesis
Msp_1114 PWY-6973 dTDP-D-olivose, dTDP-D-oliose and dTDP-D-mycarose biosynthesis
Msp_1114 PWY-6974 dTDP-L-olivose biosynthesis
Msp_1114 PWY-6976 dTDP-L-mycarose biosynthesis
Msp_1114 PWY-7104 dTDP-L-megosamine biosynthesis
Msp_1114 PWY-7301 dTDP-β-L-noviose biosynthesis
Msp_1114 PWY-7312 dTDP-D-β-fucofuranose biosynthesis
Msp_1114 PWY-7315 dTDP-N-acetylthomosamine biosynthesis
Msp_1114 PWY-7316 dTDP-N-acetylviosamine biosynthesis
Msp_1114 PWY-7318 dTDP-3-acetamido-3,6-dideoxy-α-D-glucose biosynthesis
Msp_1114 PWY-7413 dTDP-6-deoxy-α-D-allose biosynthesis
Msp_1114 PWY-7414 dTDP-α-D-mycaminose biosynthesis
Msp_1114 PWY-7440 dTDP-β-L-4-epi-vancosamine biosynthesis
Msp_1122 PWY-6121 5-aminoimidazole ribonucleotide biosynthesis I
Msp_1122 PWY-6122 5-aminoimidazole ribonucleotide biosynthesis II
Msp_1122 PWY-6277 superpathway of 5-aminoimidazole ribonucleotide biosynthesis
Msp_1122 PWY-7282 4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis (yeast)
Msp_1134 PWY-7219 adenosine ribonucleotides de novo biosynthesis
Msp_1135 PWY-7219 adenosine ribonucleotides de novo biosynthesis
Msp_1166 PWY-2301 myo-inositol biosynthesis
Msp_1166 PWY-4661 1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)
Msp_1166 PWY-6372 1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)
Msp_1166 PWY-6580 phosphatidylinositol biosynthesis I (bacteria)
Msp_1166 PWY-6664 di-myo-inositol phosphate biosynthesis
Msp_1168 PWY-5508 adenosylcobalamin biosynthesis from cobyrinate a,c-diamide II
Msp_1168 PWY-5509 adenosylcobalamin biosynthesis from cobyrinate a,c-diamide I
Msp_1168 PWY-6269 adenosylcobalamin salvage from cobinamide II
Msp_1171 PWY-6703 preQ0 biosynthesis
Msp_1177 PWY-6167 flavin biosynthesis II (archaea)
Msp_1180 PWY-5188 tetrapyrrole biosynthesis I (from glutamate)
Msp_1181 PWY-1281 sulfoacetaldehyde degradation I
Msp_1181 PWY-5482 pyruvate fermentation to acetate II
Msp_1181 PWY-5485 pyruvate fermentation to acetate IV
Msp_1181 PWY-5497 purine nucleobases degradation II (anaerobic)
Msp_1181 PWY-6637 sulfolactate degradation II
Msp_1185 PWY-6167 flavin biosynthesis II (archaea)
Msp_1185 PWY-6168 flavin biosynthesis III (fungi)
Msp_1187 PWY-6654 phosphopantothenate biosynthesis III
Msp_1191 PWY-5188 tetrapyrrole biosynthesis I (from glutamate)
Msp_1191 PWY-5189 tetrapyrrole biosynthesis II (from glycine)
Msp_1192 PWY-5194 siroheme biosynthesis
Msp_1192 PWY-7377 cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)
Msp_1193 PWY-6121 5-aminoimidazole ribonucleotide biosynthesis I
Msp_1193 PWY-6122 5-aminoimidazole ribonucleotide biosynthesis II
Msp_1193 PWY-6277 superpathway of 5-aminoimidazole ribonucleotide biosynthesis
Msp_1194 PWY-6121 5-aminoimidazole ribonucleotide biosynthesis I
Msp_1194 PWY-6122 5-aminoimidazole ribonucleotide biosynthesis II
Msp_1194 PWY-6277 superpathway of 5-aminoimidazole ribonucleotide biosynthesis
Msp_1195 PWY-6123 inosine-5'-phosphate biosynthesis I
Msp_1195 PWY-6124 inosine-5'-phosphate biosynthesis II
Msp_1195 PWY-7234 inosine-5'-phosphate biosynthesis III
Msp_1196 PWY-6749 CMP-legionaminate biosynthesis I
Msp_1200 PWY-5154 L-arginine biosynthesis III (via N-acetyl-L-citrulline)
Msp_1200 PWY-5686 UMP biosynthesis
Msp_1200 PWY-7400 L-arginine biosynthesis IV (archaebacteria)
Msp_1201 PWY-5154 L-arginine biosynthesis III (via N-acetyl-L-citrulline)
Msp_1201 PWY-5686 UMP biosynthesis
Msp_1201 PWY-7400 L-arginine biosynthesis IV (archaebacteria)
Msp_1214 PWY-5265 peptidoglycan biosynthesis II (staphylococci)
Msp_1214 PWY-6470 peptidoglycan biosynthesis V (β-lactam resistance)
Msp_1214 PWY-6471 peptidoglycan biosynthesis IV (Enterococcus faecium)
Msp_1236 PWY-5041 S-adenosyl-L-methionine cycle II
Msp_1236 PWY-6151 S-adenosyl-L-methionine cycle I
Msp_1236 PWY-6936 seleno-amino acid biosynthesis
Msp_1236 PWY-702 L-methionine biosynthesis II
Msp_1237 PWY-3841 folate transformations II
Msp_1237 PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I
Msp_1237 PWY-7187 pyrimidine deoxyribonucleotides de novo biosynthesis II
Msp_1237 PWY-7198 pyrimidine deoxyribonucleotides de novo biosynthesis IV
Msp_1237 PWY-7199 pyrimidine deoxyribonucleosides salvage
Msp_1237 PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP
Msp_1239 PWY-6167 flavin biosynthesis II (archaea)
Msp_1239 PWY-6168 flavin biosynthesis III (fungi)
Msp_1247 PWY-6123 inosine-5'-phosphate biosynthesis I
Msp_1247 PWY-6124 inosine-5'-phosphate biosynthesis II
Msp_1247 PWY-7219 adenosine ribonucleotides de novo biosynthesis
Msp_1247 PWY-7234 inosine-5'-phosphate biosynthesis III
Msp_1271 PWY-5199 factor 420 polyglutamylation
Msp_1277 PWY-6281 L-selenocysteine biosynthesis II (archaea and eukaryotes)
Msp_1291 PWY-6349 CDP-archaeol biosynthesis
Msp_1299 PWY-1042 glycolysis IV (plant cytosol)
Msp_1299 PWY-2221 Entner-Doudoroff pathway III (semi-phosphorylative)
Msp_1299 PWY-5484 glycolysis II (from fructose 6-phosphate)
Msp_1299 PWY-5723 Rubisco shunt
Msp_1299 PWY-6142 gluconeogenesis II (Methanobacterium thermoautotrophicum)
Msp_1299 PWY-6886 1-butanol autotrophic biosynthesis
Msp_1299 PWY-6901 superpathway of glucose and xylose degradation
Msp_1299 PWY-7003 glycerol degradation to butanol
Msp_1299 PWY-7124 ethylene biosynthesis V (engineered)
Msp_1299 PWY-7218 photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
Msp_1300 PWY-6749 CMP-legionaminate biosynthesis I
Msp_1301 PWY-5514 UDP-N-acetyl-D-galactosamine biosynthesis II
Msp_1307 PWY-6349 CDP-archaeol biosynthesis
Msp_1308 PWY-6610 adenine and adenosine salvage IV
Msp_1311 PWY-7221 guanosine ribonucleotides de novo biosynthesis
Msp_1312 PWY-7221 guanosine ribonucleotides de novo biosynthesis
Msp_1314 PWY-3341 L-proline biosynthesis III
Msp_1314 PWY-4981 L-proline biosynthesis II (from arginine)
Msp_1314 PWY-6344 L-ornithine degradation II (Stickland reaction)
Msp_1318 PWY-5101 L-isoleucine biosynthesis II
Msp_1318 PWY-6871 3-methylbutanol biosynthesis
Msp_1327 PWY-40 putrescine biosynthesis I
Msp_1327 PWY-43 putrescine biosynthesis II
Msp_1327 PWY-6305 putrescine biosynthesis IV
Msp_1327 PWY-6834 spermidine biosynthesis III
Msp_1330 PWY-5083 NAD/NADH phosphorylation and dephosphorylation
Msp_1330 PWY-7268 NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)
Msp_1330 PWY-7269 NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)
Msp_1332 PWY-5188 tetrapyrrole biosynthesis I (from glutamate)
Msp_1332 PWY-5189 tetrapyrrole biosynthesis II (from glycine)
Msp_1381 PWY-1042 glycolysis IV (plant cytosol)
Msp_1381 PWY-5484 glycolysis II (from fructose 6-phosphate)
Msp_1381 PWY-6886 1-butanol autotrophic biosynthesis
Msp_1381 PWY-6901 superpathway of glucose and xylose degradation
Msp_1381 PWY-7003 glycerol degradation to butanol
Msp_1382 PWY-1042 glycolysis IV (plant cytosol)
Msp_1382 PWY-5484 glycolysis II (from fructose 6-phosphate)
Msp_1382 PWY-6142 gluconeogenesis II (Methanobacterium thermoautotrophicum)
Msp_1382 PWY-7003 glycerol degradation to butanol
Msp_1383 PWY-7285 methylwyosine biosynthesis
Msp_1383 PWY-7286 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis
Msp_1386 PWY-5392 reductive TCA cycle II
Msp_1386 PWY-5537 pyruvate fermentation to acetate V
Msp_1386 PWY-5538 pyruvate fermentation to acetate VI
Msp_1386 PWY-5690 TCA cycle II (plants and fungi)
Msp_1386 PWY-5913 TCA cycle VI (obligate autotrophs)
Msp_1386 PWY-6728 methylaspartate cycle
Msp_1386 PWY-6969 TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)
Msp_1386 PWY-7384 anaerobic energy metabolism (invertebrates, mitochondrial)
Msp_1392 PWY-6147 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I
Msp_1392 PWY-6148 tetrahydromethanopterin biosynthesis
Msp_1392 PWY-6797 6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (archaea)
Msp_1392 PWY-7539 6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia)
Msp_1394 PWY-5669 phosphatidylethanolamine biosynthesis I
Msp_1398 PWY-6123 inosine-5'-phosphate biosynthesis I
Msp_1398 PWY-6124 inosine-5'-phosphate biosynthesis II
Msp_1398 PWY-7234 inosine-5'-phosphate biosynthesis III
Msp_1402 PWY-5199 factor 420 polyglutamylation
Msp_1403 PWY-5198 factor 420 biosynthesis
Msp_1404 PWY-6167 flavin biosynthesis II (archaea)
Msp_1407 PWY-5194 siroheme biosynthesis
Msp_1407 PWY-7377 cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)
Msp_1408 PWY-5188 tetrapyrrole biosynthesis I (from glutamate)
Msp_1419 PWY-7204 pyridoxal 5'-phosphate salvage II (plants)
Msp_1419 PWY-7282 4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis (yeast)
Msp_1427 PWY-7432 L-phenylalanine biosynthesis III (cytosolic, plants)
Msp_1459 PWY-4983 L-citrulline-nitric oxide cycle
Msp_1459 PWY-4984 urea cycle
Msp_1459 PWY-5 canavanine biosynthesis
Msp_1459 PWY-5154 L-arginine biosynthesis III (via N-acetyl-L-citrulline)
Msp_1459 PWY-7400 L-arginine biosynthesis IV (archaebacteria)
Msp_1467 PWY-6121 5-aminoimidazole ribonucleotide biosynthesis I
Msp_1467 PWY-6122 5-aminoimidazole ribonucleotide biosynthesis II
Msp_1467 PWY-6277 superpathway of 5-aminoimidazole ribonucleotide biosynthesis
Msp_1470 PWY-5041 S-adenosyl-L-methionine cycle II
Msp_1470 PWY-5912 2'-deoxymugineic acid phytosiderophore biosynthesis
Msp_1475 PWY-1622 formaldehyde assimilation I (serine pathway)
Msp_1475 PWY-181 photorespiration
Msp_1475 PWY-2161 folate polyglutamylation
Msp_1475 PWY-2201 folate transformations I
Msp_1475 PWY-3661 glycine betaine degradation I
Msp_1475 PWY-3661-1 glycine betaine degradation II (mammalian)
Msp_1475 PWY-3841 folate transformations II
Msp_1475 PWY-5497 purine nucleobases degradation II (anaerobic)
Msp_1483 PWY-6167 flavin biosynthesis II (archaea)
Msp_1483 PWY-6168 flavin biosynthesis III (fungi)
Msp_1498 PWY-1723 formaldehyde oxidation V (H4MPT pathway)
Msp_1498 PWY-1861 formaldehyde assimilation II (RuMP Cycle)
Msp_1498 PWY-5686 UMP biosynthesis
Msp_1501 PWY-6938 NADH repair
Msp_1511 PWY-6893 thiamin diphosphate biosynthesis II (Bacillus)
Msp_1511 PWY-6894 thiamin diphosphate biosynthesis I (E. coli)
Msp_1511 PWY-6896 thiamin salvage I
Msp_1511 PWY-6897 thiamin salvage II
Msp_1513 PWY-5269 cardiolipin biosynthesis II
Msp_1513 PWY-5668 cardiolipin biosynthesis I
Msp_1537 PWY-6482 diphthamide biosynthesis (archaea)
Msp_1537 PWY-7546 diphthamide biosynthesis (eukaryotes)
Msp_1561 PWY-7377 cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)
Msp_1563 PWY-7377 cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)
Msp_1564 PWY-6893 thiamin diphosphate biosynthesis II (Bacillus)
Msp_1564 PWY-6894 thiamin diphosphate biosynthesis I (E. coli)
Msp_1564 PWY-6896 thiamin salvage I
Msp_1564 PWY-6897 thiamin salvage II
Msp_1576 PWY-5101 L-isoleucine biosynthesis II
Msp_1576 PWY-5103 L-isoleucine biosynthesis III
Msp_1576 PWY-5104 L-isoleucine biosynthesis IV
Msp_1576 PWY-7111 pyruvate fermentation to isobutanol (engineered)
Msp_1578 PWY-2941 L-lysine biosynthesis II
Msp_1578 PWY-2942 L-lysine biosynthesis III
Msp_1578 PWY-5097 L-lysine biosynthesis VI
Msp_1579 PWY-2941 L-lysine biosynthesis II
Msp_1579 PWY-5097 L-lysine biosynthesis VI
Msp_1587 PWY-7377 cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)