LOCUS       NC_009620            1570951 bp    DNA     circular CON 10-JUN-2013
DEFINITION  Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence.
ACCESSION   NC_009620
VERSION     NC_009620.1  GI:150375726
DBLINK      Project: 58549
            BioProject: PRJNA58549
KEYWORDS    .
SOURCE      Sinorhizobium medicae WSM419
  ORGANISM  Sinorhizobium medicae WSM419
            Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
            Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
REFERENCE   1  (bases 1 to 1570951)
  AUTHORS   Reeve,W., Chain,P., O'Hara,G., Ardley,J., Nandesena,K., Brau,L.,
            Tiwari,R., Malfatti,S., Kiss,H., Lapidus,A., Copeland,A., Nolan,M.,
            Land,M., Hauser,L., Chang,Y.J., Ivanova,N., Mavromatis,K.,
            Markowitz,V., Kyrpides,N., Gollagher,M., Yates,R., Dilworth,M. and
            Howieson,J.
  TITLE     Complete genome sequence of the Medicago microsymbiont Ensifer
            (Sinorhizobium) medicae strain WSM419
  JOURNAL   Stand Genomic Sci 2 (1), 77-86 (2010)
   PUBMED   21304680
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570951)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2007) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 1570951)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Glavina del Rio,T.,
            Dalin,E., Tice,H., Pitluck,S., Chain,P., Malfatti,S., Shin,M.,
            Vergez,L., Schmutz,J., Larimer,F., Land,M., Hauser,L., Kyrpides,N.,
            Mikhailova,N., Reeve,W. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2007) US DOE Joint Genome Institute, 2800
            Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CP000739.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4001622
            Source DNA and bacteria available from Wayne Reeve
            (reeve@murdoch.edu.au)
            Contacts: Wayne Reeve (reeve@murdoch.edu.au)
                      Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LLNL
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1570951
                     /organism="Sinorhizobium medicae WSM419"
                     /mol_type="genomic DNA"
                     /strain="WSM419"
                     /db_xref="taxon:366394"
                     /plasmid="pSMED01"
     gene            197..3505
                     /locus_tag="Smed_3575"
                     /db_xref="GeneID:5317878"
     CDS             197..3505
                     /locus_tag="Smed_3575"
                     /note="conjugal transfer system TraA; oriT nicking enzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="Dtr system oriT relaxase"
                     /protein_id="YP_001312323.1"
                     /db_xref="GI:150375727"
                     /db_xref="InterPro:IPR005053"
                     /db_xref="InterPro:IPR014136"
                     /db_xref="GeneID:5317878"
                     /translation="MAVPHFSVSLITRGSGRSAVLSAAYRHCAKMAYQREARTIDYTR
                     KTGLLHEEFVIPDNAPEWLQSMITDRSVSDAAEAFWNKAEDFEKRSDAQLAKEVTIAL
                     PIELTSAQNIALVRDFVEQHISAKGMVADWVYHDAPGNPHVHLMTTLRPLTQQGFGAK
                     KVAVLGPDGYPIRNDAGKIVYELWAGSLDDFNALRDGWFACQNRHLTLAGLDLRIDGR
                     SFEKQGIELAPTLHLGAGTKAIERKATAEAKTLSLERLQLQEDLRSENARRLQRRPEI
                     VLDLITRERSVFDERDVAKILHRYVDDPAVFRSLMARILQSPETLQLERERTAFATGI
                     RAPAKYTTRALIRLEAEMANRAIWLSRQSSHRLREAVLEATLARHSRLSDEQKTAIEH
                     VAKAGRIAAVIGRAGAGKTTMMKAAREAWEAAGYRVVGGALAGKAAEGLEKEAGIISR
                     TLSAWELRWSQGRNQLDARTVFILDEAGMVSSRQMACFMEAATRTGAKLVLVGDPEQL
                     QPIEAGAAFRAIADRIGYAELETIYRQREQWMRDASLDLARGNVGKAVEAYRANGRMI
                     GAELKAEAVRNLIVDWNRDYDPTKTTLILAHLRRDVRMLNEMARSKLVERGIVGEGFA
                     FRTADGNRNFAAGDQIVFLKNEGSLGVKNGMLGKIVEASPNRVVAEIGAGEHHRQVII
                     EQRFYNNLDHGYATTIHKSQGATVDRVKVLASLSLDRHLVYVAMTRHRDNLDVYYGAR
                     SFARAGGLIQVLSRKNSKETTLDYEKATFYRQALRFAEARGLHLLNVARTIARDRLAW
                     TARQSSRLADLAHRLVRIGRKLGLAAGTNPINSQNSKETRPMVAGIATHPESVEQAVA
                     DKLAADPGLKKQWDDVSTRFHLVYAHPAAAFKAVNIDVMLKDETAAKATLSKIAKQPD
                     SYGALKGKTGLLASRADRQDRERAVRNVPALVQSLDGYMRQRGSAERRYRAEELEARR
                     KVAIDIPALSPGARQILERVRDAIDRNDLSAALEFARADRHVKAELDGFANAVDARFG
                     KRTFLPLSARDTNGDTFTSVTAGMHPGQRLEVESAWKAMRTVQQLSAHERTTEALKLS
                     ETLRLSKSQGLSLR"
     misc_feature    197..3502
                     /locus_tag="Smed_3575"
                     /note="Dtr system oriT relaxase; Provisional; Region:
                     PRK13826"
                     /db_xref="CDD:237524"
     misc_feature    245..925
                     /locus_tag="Smed_3575"
                     /note="MobA/MobL family; Region: MobA_MobL; pfam03389"
                     /db_xref="CDD:217529"
     misc_feature    1337..1903
                     /locus_tag="Smed_3575"
                     /note="AAA domain; Region: AAA_30; pfam13604"
                     /db_xref="CDD:222258"
     misc_feature    2114..2404
                     /locus_tag="Smed_3575"
                     /note="Family description; Region: UvrD_C_2; pfam13538"
                     /db_xref="CDD:222209"
     gene            4121..4504
                     /locus_tag="Smed_3576"
                     /db_xref="GeneID:5318081"
     CDS             4121..4504
                     /locus_tag="Smed_3576"
                     /note="KEGG: sme:SMa1798 Kup2 potassium uptake protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Kup2 potassium uptake protein"
                     /protein_id="YP_001312324.1"
                     /db_xref="GI:150375728"
                     /db_xref="GeneID:5318081"
                     /translation="MTDSLDHAQANNMPQFLGLTVGAIGVVYGDIGTSSLYAFREALR
                     TFGPGGVGRDEVIGLVSLVLCTLTAIATLKYVIFLLRADNDGEGGTLSLLALLLKKGT
                     KNPVLMFFAGILVFFLMFSLTKETT"
     misc_feature    4121..>4462
                     /locus_tag="Smed_3576"
                     /note="K+ potassium transporter; Region: K_trans; cl15781"
                     /db_xref="CDD:247066"
     gene            4501..4878
                     /locus_tag="Smed_3577"
                     /db_xref="GeneID:5317877"
     CDS             4501..4878
                     /locus_tag="Smed_3577"
                     /note="PFAM: protein of unknown function DUF454;
                     KEGG: sme:SMb20557 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312325.1"
                     /db_xref="GI:150375729"
                     /db_xref="InterPro:IPR007401"
                     /db_xref="GeneID:5317877"
                     /translation="MNLSVRLALLGLAWVMVGLATAGIFLPLLPTTPFLLLAAWLFSR
                     SSPRLEQWLAGHALFGPPLRDWRDDGAIARRNKICAILLMALGFAYFWLAIEPPAIGL
                     LAVAAIMIACGIFIATRPEPPNK"
     sig_peptide     4501..4569
                     /locus_tag="Smed_3577"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.974 at
                     residue 23"
     misc_feature    4513..4866
                     /locus_tag="Smed_3577"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG2832"
                     /db_xref="CDD:225388"
     gene            complement(5353..6639)
                     /locus_tag="Smed_3578"
                     /db_xref="GeneID:5318082"
     CDS             complement(5353..6639)
                     /locus_tag="Smed_3578"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb20538 putative solute-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312326.1"
                     /db_xref="GI:150375730"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5318082"
                     /translation="MLLNRRGFMAGAAGAAAGVALGSRTTLAAESVQLRAMWWGSNDR
                     SKRTLAVAKLFAEANPDIRIIGESLSGDGYWTKLATQMAGRSIADIFQLEPSTISDYS
                     KRGACMALDPFISSALDVDAFGKDVLKLTTVDGKLWGVGLGLNSFALFYDADAFARAG
                     IDPPGIDTTWAEYAEIAVEMTKAVGKKSAGGGPYGARYAYVFDAWLRQRGSSLYTDSG
                     LGFGVEEAKEWYAYWEELRKRGGTVGADIQTLDQNTIDTNCLALGYSAMGMAYSNQMV
                     GYQLIMKSKLGIGMLPRAEKGGPSGHYYRPALIWSIGASTEHGEEAAKFINFFVNDVE
                     AGKILGVERGVPMSPTVREAILPSLNPTETETVKYINGLKDQVGSYPSPAPLGATEFD
                     QRVLRPIADELAFERISIGDAATRLVEEGRATVRAG"
     sig_peptide     complement(6553..6639)
                     /locus_tag="Smed_3578"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.987 at
                     residue 29"
     misc_feature    complement(5362..6567)
                     /locus_tag="Smed_3578"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     misc_feature    complement(<6163..6492)
                     /locus_tag="Smed_3578"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     gene            6785..7819
                     /locus_tag="Smed_3579"
                     /db_xref="GeneID:5318083"
     CDS             6785..7819
                     /locus_tag="Smed_3579"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: sme:SMb20537 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001312327.1"
                     /db_xref="GI:150375731"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318083"
                     /translation="MIERPSRRLRQADIAAHAGVSVSTVSRVLANEPGISEDVRVQIF
                     KVASELGYPLKAGTAAGSRALALIASNGVTGGLSAFYQGIVDGLRSEAAAQGMSFDIR
                     LINEMKATPQVVGEHLESVGAQGLFLVGIDPSEALGDWLVESRLPVVLVNGVDPQLRF
                     DGISPPNFFGAFAATRMLLDAGHRRILHLTGSHRHTIRERVRGFEAAIACAEGCAARI
                     VRLPFETNSSAEAHAATLDALAVDGNFTAAFCMNDFIAVGVLEAVTELGRRVPDDFAI
                     IGFDDLPCAEMANPRLSTMHVDRAALGREAVGMMQFRFAHPDVPARHVSHAVTPVPGG
                     TIARRTTHDL"
     misc_feature    6818..>6940
                     /locus_tag="Smed_3579"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(6818..6820,6842..6856,6860..6865,6872..6874,
                     6887..6892,6899..6901,6938..6940)
                     /locus_tag="Smed_3579"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    6821..7801
                     /locus_tag="Smed_3579"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    7022..7756
                     /locus_tag="Smed_3579"
                     /note="Ligand binding domain of the LacI tanscriptional
                     regulator family belonging to the type I
                     periplasmic-binding fold protein superfamily; Region:
                     PBP1_LacI_sugar_binding_like; cd06267"
                     /db_xref="CDD:107262"
     misc_feature    order(7022..7027,7034..7036,7169..7171,7238..7240,
                     7277..7279,7382..7384,7457..7459,7622..7624,7673..7675)
                     /locus_tag="Smed_3579"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107262"
     misc_feature    order(7025..7033,7040..7045,7049..7054,7073..7087,
                     7091..7093,7124..7126,7133..7135,7142..7150,7466..7468,
                     7553..7555,7565..7567,7574..7579)
                     /locus_tag="Smed_3579"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107262"
     gene            7809..9662
                     /locus_tag="Smed_3580"
                     /db_xref="GeneID:5318084"
     CDS             7809..9662
                     /locus_tag="Smed_3580"
                     /note="KEGG: sme:SMb20536 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312328.1"
                     /db_xref="GI:150375732"
                     /db_xref="GeneID:5318084"
                     /translation="MTYDPASANPLAGNPLQKRGDMQSALLDLFDPLLPYFSTGNARV
                     RLDAAAAHFDRAAADLEGFARPLWGLAPFAAGGGDFGHWDRYAEGIANGTDPQHPEFW
                     GQVNGRDQRMVELAALGFALALVPEKLWDPLSRRARENLVAYLLHARTFDYADNNWKF
                     FRIFVDIALDRLGIDHDRSLTRSYLAELDGFYIADGWYRDGNVRRVDHYIAFAMHFYG
                     LIYARLVDDDHAKRYRERAISFAQDFRHWFAEDGATLPFGRSLTYRFACAGFWSALAF
                     ADLEALPWGEIKGLCLRHLRWWADKPIAHRDGVLSIGYGYPNLLMSESYNSAGSPYWA
                     FKAFLPLATGENHPFWTSTEAPLQQSTEPLDLRHAGMVMMPVNGDVVALSSGQENRQM
                     RFGSEKYAKFAYSARYAFSIESDERGFVGGAFDSMLAFSDDGIHYRVREANEEVLIAG
                     DVLFSKWSPWPDVLVETWLIPSSPWHVRVHRITTPRPLETAEGGFAIDRRDFDADTLF
                     AAEGTAHAIGAEDFSGIRDLGSTVPREGIIQKAPPNTNLIAARTLVPQLRTSIPSGET
                     VLGCAVIAFRNNPALAEAWPSPPVMPDIEKLVAIRAEGLNVSTMLAPGRIP"
     misc_feature    7809..9191
                     /locus_tag="Smed_3580"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4289"
                     /db_xref="CDD:226739"
     gene            9659..10666
                     /locus_tag="Smed_3581"
                     /db_xref="GeneID:5318085"
     CDS             9659..10666
                     /locus_tag="Smed_3581"
                     /note="PFAM: D-isomer specific 2-hydroxyacid dehydrogenase
                     NAD-binding;
                     KEGG: sme:SMb20535 putative dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding D-isomer specific 2-hydroxyacid
                     dehydrogenase"
                     /protein_id="YP_001312329.1"
                     /db_xref="GI:150375733"
                     /db_xref="InterPro:IPR006140"
                     /db_xref="GeneID:5318085"
                     /translation="MSLPTVAFAMQPERTRYVLTPELLKRLAGLARILDERPITEFDE
                     RAKRLLGEAEILVTGWGAPFFDEAALARAPHLRLIVHAAGTIKGLVGRSVFEAGIKVS
                     HAAEANAVPVAEFTLAAVIFAGKRVFQFRDIYVADRGRGRIQTLQGEAIGNHRRIVGI
                     VGASRIGRRVIELLRLFDYQLLLYDPLISEAEAEALGAEKVDLAALMARSDIVSLHAP
                     LLPETRHMIDARQLALMKEGATLINTARGALVNEAALIAKLQTGSINAVIDVTHPEIP
                     EGNSPLYDLPNVFLTPHIAGAIGLERRRLGEMAVDEVARFLEGKQLLFEVLKQDLARI
                     A"
     misc_feature    9674..10663
                     /locus_tag="Smed_3581"
                     /note="Putative D-isomer specific 2-hydroxyacid
                     dehydrogenases; Region: 2-Hacid_dh_8; cd12167"
                     /db_xref="CDD:240644"
     misc_feature    9680..10657
                     /locus_tag="Smed_3581"
                     /note="Phosphoglycerate dehydrogenase and related
                     dehydrogenases [Amino acid transport and metabolism];
                     Region: SerA; COG0111"
                     /db_xref="CDD:223189"
     misc_feature    order(9836..9838,9905..9913,9980..9982,10394..10396,
                     10535..10537)
                     /locus_tag="Smed_3581"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:240644"
     misc_feature    order(9908..9910,9980..9982,9992..9994,10142..10156,
                     10208..10216,10304..10312,10325..10327,10388..10396,
                     10463..10468,10535..10537,10541..10546)
                     /locus_tag="Smed_3581"
                     /note="putative NAD binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240644"
     misc_feature    order(10394..10396,10478..10480,10535..10537)
                     /locus_tag="Smed_3581"
                     /note="catalytic site [active]"
                     /db_xref="CDD:240644"
     gene            10663..11472
                     /locus_tag="Smed_3582"
                     /db_xref="GeneID:5318086"
     CDS             10663..11472
                     /locus_tag="Smed_3582"
                     /note="PFAM: Xylose isomerase domain protein TIM barrel;
                     KEGG: sme:SMb20534 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase domain-containing protein"
                     /protein_id="YP_001312330.1"
                     /db_xref="GI:150375734"
                     /db_xref="InterPro:IPR012307"
                     /db_xref="GeneID:5318086"
                     /translation="MIGIEPALCSVTFRKMPADEIVALAVEARLAAVEWAGDAHVSPG
                     DLPAARAVARRCENAGLKTSYGSYIAPPTDDFAAFKSALETAVALGASNIRIWAGTRE
                     RDSSNYSAEERRHAAEAIRQMGAEAARHGVTVSLEYHPQSLTDETLSAQSLIEAVGHP
                     NVYLYWQPRPGLPLKEALTEIAQVGEHISHVHVFAWDRCRNRFALATAADYWRTVLTA
                     LPQSRWRGRRFAMLEFVAGDDPAAFLADAGTLRQILRVELSLRTSGDADGD"
     misc_feature    10771..11241
                     /locus_tag="Smed_3582"
                     /note="Xylose isomerase-like TIM barrel; Region:
                     AP_endonuc_2; pfam01261"
                     /db_xref="CDD:216395"
     gene            11544..11954
                     /locus_tag="Smed_3583"
                     /db_xref="GeneID:5318574"
     CDS             11544..11954
                     /locus_tag="Smed_3583"
                     /note="KEGG: mlo:mll2216 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312331.1"
                     /db_xref="GI:150375735"
                     /db_xref="GeneID:5318574"
                     /translation="MQLQPIVTTPTATTDAITDAEAGALARAVVNLSRAWKLSDAESC
                     ILLGGMSPRTWARWKDGDIGRIDRDLRMRMAHLMGIHKGLRYLFKEAARGYAWMRKPN
                     AAFGGFSALDLMLRGEISDLSALREWLDAERSAW"
     misc_feature    11802..11951
                     /locus_tag="Smed_3583"
                     /note="Protein of unknown function (DUF2384); Region:
                     DUF2384; pfam09722"
                     /db_xref="CDD:204292"
     gene            11948..12646
                     /locus_tag="Smed_3584"
                     /db_xref="GeneID:5318575"
     CDS             11948..12646
                     /locus_tag="Smed_3584"
                     /note="PFAM: RES domain protein;
                     KEGG: mlo:mll2215 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RES domain-containing protein"
                     /protein_id="YP_001312332.1"
                     /db_xref="GI:150375736"
                     /db_xref="InterPro:IPR014914"
                     /db_xref="GeneID:5318575"
                     /translation="MVSGLAVRKRVQWQQTYRIIRSIYPPVDLFEDIADPRDWEALAA
                     VEEKTNPRIRLEIGDLGKIPAARRVSGPGASFVMAPFVHCSVLRPGRFTNGSYGIYYA
                     GDSEVVAVAETIYHHEKFMRATNEEPGWTADFRILIGSVDRDLDDVSAVPGVLHPDDY
                     TASHIEGRDLRAAGSDGLVWDSVRMRGGRCIGAFWPDVITIPIQGRHYGYHWDGTRVD
                     FVRQYDTGRVLAVT"
     misc_feature    12206..12529
                     /locus_tag="Smed_3584"
                     /note="RES domain; Region: RES; smart00953"
                     /db_xref="CDD:214933"
     gene            complement(12701..13468)
                     /locus_tag="Smed_3585"
                     /db_xref="GeneID:5318576"
     CDS             complement(12701..13468)
                     /locus_tag="Smed_3585"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR;
                     KEGG: sme:SMa0719 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001312333.1"
                     /db_xref="GI:150375737"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR002424"
                     /db_xref="GeneID:5318576"
                     /translation="MSTYKDIFSLKGRTALVTGSSRGIGAAIAQAYAAYGARVVLHGQ
                     KPGATAGVEQAISAAGGDAVSIQGELSPPGAGGDLISAAETAAGPLDILVINASAQIN
                     GSFDDVTPEDFATQINVNLRSTVEMLQTALPGMAERGWGRVVNIGSINQLRPKSIVSI
                     YAATKAAQHNLIQSLARDYAPRGVLLNTLAPGLIDTDRNAARRDGDPEGWENYVRTLN
                     WMGRAGAPDEMVGAALFLASDACSFMTGEAVVMSGGY"
     sig_peptide     complement(13373..13468)
                     /locus_tag="Smed_3585"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.880) with cleavage site probability 0.374 at
                     residue 32"
     misc_feature    complement(12707..13444)
                     /locus_tag="Smed_3585"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Validated; Region: fabG; PRK05653"
                     /db_xref="CDD:235546"
     misc_feature    complement(12719..13426)
                     /locus_tag="Smed_3585"
                     /note="classical (c) SDRs; Region: SDR_c; cd05233"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(12878..12883,12887..12898,12974..12976,
                     12986..12988,13025..13033,13112..13114,13175..13183,
                     13259..13267,13334..13342,13397..13408,13412..13414))
                     /locus_tag="Smed_3585"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(12974..12976,12986..12988,13025..13027,
                     13109..13111))
                     /locus_tag="Smed_3585"
                     /note="active site"
                     /db_xref="CDD:212491"
     gene            complement(13478..15187)
                     /locus_tag="Smed_3586"
                     /db_xref="GeneID:5318577"
     CDS             complement(13478..15187)
                     /locus_tag="Smed_3586"
                     /note="PFAM: regulatory protein IclR;
                     SMP-30/Gluconolaconase/LRE domain protein; Transcriptional
                     regulator IclR;
                     KEGG: sme:SMa0717 putative calcium binding transcriptional
                     regulatory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="SMP-30/gluconolaconase/LRE domain-containing
                     protein"
                     /protein_id="YP_001312334.1"
                     /db_xref="GI:150375738"
                     /db_xref="InterPro:IPR005471"
                     /db_xref="InterPro:IPR005511"
                     /db_xref="InterPro:IPR013658"
                     /db_xref="InterPro:IPR014757"
                     /db_xref="GeneID:5318577"
                     /translation="MDDKAVLGGLEDRGAPAGAAALAKGLALLDLIAEAPKPLRFADL
                     QKMSGVPKPTLARMLKTLMVFRLIRQDEATGAYLLGHRFIELSHRVWDKFDLVSAAAP
                     ELERLSAELGETVALCRLDGHRVVYLEERSSGGLGVLIAVGRRVPVHCTAAGKALLAF
                     QEPSFARSLAGQLDYDRFTPQTITDPQALEADLVLTRARGYAVSYEEHLAGVNTVAAP
                     IAGRDGVPLGALVVLGPASRLDSSAIHPVGRELMAAARRITGTVGAVAISSGPRPRTR
                     AGGQSDVQCVLPWGAQLGEAPVWVGREKRLYWVDILHPAVHRFDPVTGKNETCNTAKL
                     VSAVLPSEDGRLVVASQDGVERFDFERGLFTRFAEPEPGVPENRLNDAKVDPHGRLWV
                     GSMRLDVSRPTGSLYRLTKTGEVARAESGFTVANGLAWSPDSSTFYFVDTVPGIIYAY
                     DFDAREGSIANRRVFVTVPEAEGRPDGLAVDADGGVWCAIWDGWRVNRYRPDGRLDRA
                     VELPVPRPTSVAFGGDDLATLFITSARTRLPASTLTEAPLSGGIFACNPGERGLATSL
                     FGV"
     misc_feature    complement(14396..15088)
                     /locus_tag="Smed_3586"
                     /note="Transcriptional regulator [Transcription]; Region:
                     IclR; COG1414"
                     /db_xref="CDD:224332"
     misc_feature    complement(14864..15088)
                     /locus_tag="Smed_3586"
                     /note="helix_turn_helix isocitrate lyase regulation;
                     Region: HTH_ICLR; smart00346"
                     /db_xref="CDD:214629"
     misc_feature    complement(14405..14776)
                     /locus_tag="Smed_3586"
                     /note="Bacterial transcriptional regulator; Region: IclR;
                     pfam01614"
                     /db_xref="CDD:201890"
     misc_feature    complement(13583..14311)
                     /locus_tag="Smed_3586"
                     /note="SMP-30/Gluconolaconase/LRE-like region; Region:
                     SGL; pfam08450"
                     /db_xref="CDD:219847"
     gene            complement(15166..16146)
                     /locus_tag="Smed_3587"
                     /db_xref="GeneID:5318578"
     CDS             complement(15166..16146)
                     /locus_tag="Smed_3587"
                     /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase;
                     dTDP-4-dehydrorhamnose reductase; NmrA family protein;
                     Male sterility domain;
                     KEGG: sme:SMa0715 putative UDP-glucose 4-epimerase"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="YP_001312335.1"
                     /db_xref="GI:150375739"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR008030"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318578"
                     /translation="MKVLVTGSAGRVGSFVVRQLLEAGHQVRGFDLRSALIDDAGFDE
                     VVGAFDDREAAARACEGIDAVLHLGAFMSWLASDRDRLFQANVEGTRIVAEAAVAAKV
                     GRFVFASSGEVYPENRPEFQPITEDHPKEPLSPYGLTKLLGEELVTFQGRVSSMETVI
                     LRFSHTQNADELLDPDSFFSGPRFFLRPKIKQQEAFGNRTAADLLRAADPGRPALVLT
                     RNENGRPFKMHITDTRDMARGVLLALSHPKAAGGVFNLGATDPVDFAEVLPVMADRIG
                     WPLVTVDLPGSGVWYHTSNQRIREALGFEPKWPIMRMLDEAVAAWTTRQS"
     misc_feature    complement(15172..16146)
                     /locus_tag="Smed_3587"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    complement(15193..16143)
                     /locus_tag="Smed_3587"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    complement(order(15616..15621,15655..15660,15727..15729,
                     15739..15741,15817..15825,15937..15945,16051..16053,
                     16054..16056,16111..16113,16117..16122,16126..16128))
                     /locus_tag="Smed_3587"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    complement(order(15727..15729,15739..15741,15817..15819,
                     15889..15891))
                     /locus_tag="Smed_3587"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            complement(16148..17236)
                     /locus_tag="Smed_3588"
                     /db_xref="GeneID:5318968"
     CDS             complement(16148..17236)
                     /locus_tag="Smed_3588"
                     /note="PFAM: ABC transporter related; Transport-associated
                     OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: atc:AGR_pAT_681 probable sugC protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312336.1"
                     /db_xref="GI:150375740"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5318968"
                     /translation="MAGISIQNVYKNYGALNVLKEFSLEISDGEFVVLVGPSGCGKST
                     MLKILAGLEPASGGKILIGDKDVTDLAPGDRDIAMVFQNYALYPHLTVGQNIGFGLKM
                     RGMPKAEIDKRVHAVARILAVEHLLDRRPKALSGGQRQRVALGRAIVREPRAFLMDEP
                     LSNLDAKLRVHTRAEISALHKRIGVTTVYVTHDQIEAMTMADRVVIMRDGVIQQIADP
                     DTLFARPANLFVAGFIGSPGMNFMSARIEGGMLTLFGQNFATQKGARDGEVIVGIRPE
                     HLSLGQGDVTFAVRPTLVESLGSEKYIYFDPGENAYGEAARDEERGKGLIARIAHSGP
                     VREGDELTLSFDPSEIHLFDPKTEKAVD"
     misc_feature    complement(16169..17236)
                     /locus_tag="Smed_3588"
                     /note="ABC-type sugar transport systems, ATPase components
                     [Carbohydrate transport and metabolism]; Region: MalK;
                     COG3839"
                     /db_xref="CDD:226359"
     misc_feature    complement(16589..17227)
                     /locus_tag="Smed_3588"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    complement(17108..17131)
                     /locus_tag="Smed_3588"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(order(16661..16663,16760..16765,16991..16993,
                     17105..17113,17117..17122))
                     /locus_tag="Smed_3588"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(16991..17002)
                     /locus_tag="Smed_3588"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(16808..16837)
                     /locus_tag="Smed_3588"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(16760..16777)
                     /locus_tag="Smed_3588"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(16742..16753)
                     /locus_tag="Smed_3588"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(16655..16675)
                     /locus_tag="Smed_3588"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(16178..16426)
                     /locus_tag="Smed_3588"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            complement(17238..18068)
                     /locus_tag="Smed_3589"
                     /db_xref="GeneID:5318969"
     CDS             complement(17238..18068)
                     /locus_tag="Smed_3589"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMa0711 putative ABC transporter permease
                     protein, MalFG family"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001312337.1"
                     /db_xref="GI:150375741"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318969"
                     /translation="MQRTTLQTLSLYAGLAVVCGVLLFPIYWLFVTALSTLAEIRQLP
                     PSFWPADPQWSTFAKVATERPILLWLWNSTLAALGSVALSMVVSVFAGYSLSRFSVKG
                     GRSLGLFILTAKMLPATLLVIPLFGIFRSMGLIGSLWSLVLAHATLIIPFTTWMLKGY
                     FDTIPRELEQAAMVDGCSPLGALFRVVLPVATPGLAATALYAFVLSWADYAYARTFLT
                     NAQGSWTANLGITTMKGEYVTDWNEISAAAVFVSVPIILIYLFLERYLVGGLTAGAEK
                     "
     sig_peptide     complement(17952..18068)
                     /locus_tag="Smed_3589"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.857) with cleavage site probability 0.638 at
                     residue 39"
     misc_feature    complement(17241..18062)
                     /locus_tag="Smed_3589"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    complement(17301..17861)
                     /locus_tag="Smed_3589"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(17301..17306,17313..17318,17325..17330,
                     17334..17339,17346..17351,17379..17384,17421..17426,
                     17436..17447,17466..17468,17475..17480,17520..17522,
                     17571..17573,17580..17585,17595..17597,17601..17606,
                     17613..17615,17619..17621,17625..17630,17691..17693,
                     17697..17702,17709..17738,17742..17753,17781..17783,
                     17796..17801,17808..17813))
                     /locus_tag="Smed_3589"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(17430..17447,17691..17735))
                     /locus_tag="Smed_3589"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(17349..17351,17379..17381,17388..17390,
                     17424..17426,17643..17645,17691..17693))
                     /locus_tag="Smed_3589"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(17499..17501,17511..17516,17532..17570))
                     /locus_tag="Smed_3589"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(18080..18985)
                     /locus_tag="Smed_3590"
                     /db_xref="GeneID:5318970"
     CDS             complement(18080..18985)
                     /locus_tag="Smed_3590"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMa0710 putative ABC transporter, sugar permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312338.1"
                     /db_xref="GI:150375742"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318970"
                     /translation="MSVRFLDLARPSRQHWLGYLLLLPAVALVALIIVYPLFVSLDLS
                     FQKIGMATLSAPRKPFTLENYHKLFTSPDFWNSCWVTIKLVLVVSAACFAVGLGTALL
                     VNNRFKGRTLARLFVALPWAVPEVIAVVIFAWIFDSSFGLMNWLFIKLGITSQMVNWF
                     SEPTAAFWVVAITMIWKGYPFVSIMTLAGLQSIPEDFYNAAKVDGANAFQRFWYITIP
                     VLMPVLGVTSVLVVLWVFRDFSIIKVLTDGGPLKATQTLSIMTYDQAFGFFNMGYASA
                     IGIVTLVLCVVASLLMLGRKSQAMY"
     misc_feature    complement(18128..18751)
                     /locus_tag="Smed_3590"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(18128..18133,18140..18145,18152..18157,
                     18161..18166,18173..18178,18206..18211,18254..18259,
                     18266..18277,18296..18298,18305..18310,18350..18352,
                     18401..18403,18410..18415,18425..18427,18431..18436,
                     18443..18445,18452..18454,18458..18463,18587..18589,
                     18593..18598,18605..18634,18638..18649,18677..18679,
                     18689..18694,18701..18706))
                     /locus_tag="Smed_3590"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(18260..18277,18587..18631))
                     /locus_tag="Smed_3590"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(18176..18178,18206..18208,18215..18217,
                     18257..18259,18476..18478,18587..18589))
                     /locus_tag="Smed_3590"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(18329..18331,18341..18346,18362..18400))
                     /locus_tag="Smed_3590"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(19283..20548)
                     /locus_tag="Smed_3591"
                     /db_xref="GeneID:5318971"
     CDS             complement(19283..20548)
                     /locus_tag="Smed_3591"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMa0709 putative ABC sugar transport system
                     sugar binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312339.1"
                     /db_xref="GI:150375743"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5318971"
                     /translation="MKIIRKYAVATTVAAMLACTALPVTAKAEVLKFVSWQKDEKGIG
                     DWWGTVVKEWEAKHPGNTIEWTKVERSAYADTMTTLFAGGTPPDIVHLASFEFQTFAN
                     NGWLEDLGPWVEKSGLNLDGWSGQDICNFQDTTVCIMMLYYGTIFGYNEEMLKQAGVA
                     VPTNYEEFLAAARATTKDLNGDGIVDQFGTGHETKGGGGQYIAEMASYLFDAGARFTN
                     AEGKVTIDTPEMVEGLTRWKTVVKESLTPRDLSAGEVRKLFADGKIALKVDGPWIYSI
                     MQQGAAKDKLKLASVPFDPPLGGSSNILAMPSEISDEKKQLVWDFIAIATSDKFQTSF
                     ATLAASTPPSPRADLTEAKAQIPHFDLMAKSQKAAAEHKIDRIPTGLEIQFNEFSKMI
                     QEEAQRMIIEDLDPAAVAKTMHEKAEALQ"
     misc_feature    complement(19289..20548)
                     /locus_tag="Smed_3591"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     sig_peptide     complement(20468..20548)
                     /locus_tag="Smed_3591"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.830 at
                     residue 27"
     misc_feature    complement(19556..20419)
                     /locus_tag="Smed_3591"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     gene            complement(20581..21750)
                     /locus_tag="Smed_3592"
                     /db_xref="GeneID:5318972"
     CDS             complement(20581..21750)
                     /locus_tag="Smed_3592"
                     /note="PFAM: Mandelate racemase/muconate lactonizing
                     protein;
                     KEGG: sme:SMa0708 putative isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing protein"
                     /protein_id="YP_001312340.1"
                     /db_xref="GI:150375744"
                     /db_xref="InterPro:IPR001354"
                     /db_xref="InterPro:IPR006025"
                     /db_xref="InterPro:IPR013341"
                     /db_xref="InterPro:IPR013342"
                     /db_xref="GeneID:5318972"
                     /translation="MSDRVKKIESFTLTLPRDKPYLGKPRPGEEPNGRGYLVRKGNRT
                     VYPTFDRSVLVRIETENGAVGWGETYGLVAPRATMEIIDDLLADFTVGRDPFDAAAIH
                     DDLYDLMRVRGYTGGFYVDALAAIDIALWDLAGKLAGMPVCKLLGGRRRDRIDAYISG
                     LPEDTRGKRAELAASWQAKGFSSFKFASPVADDGVASEIETLRERLGDGARIACDMHW
                     AQTASEAIALIRAMEPHGLWFAEAPVRTEDMEGLARVAASVPTAIAVGEEWRTVYDMV
                     PRVARNALAIVQPEMGHKGITQFMRIGECAHAHHIKIIPHATIGSGIFLAASLQASAA
                     LANVDCHEFQHSIFEPNRRLLDGDMDCVEGQYILPTGPGLGVEPSKEALALLKRN"
     misc_feature    complement(20620..21624)
                     /locus_tag="Smed_3592"
                     /note="Mandelate racemase (MR)-like subfamily of the
                     enolase superfamily. Enzymes of this subgroup share three
                     conserved carboxylate ligands for the essential divalent
                     metal ion (usually Mg2+), two aspartates and a glutamate,
                     and conserved catalytic residues; Region: MR_like;
                     cd03316"
                     /db_xref="CDD:239432"
     misc_feature    complement(20587..21612)
                     /locus_tag="Smed_3592"
                     /note="L-alanine-DL-glutamate epimerase and related
                     enzymes of enolase superfamily [Cell envelope biogenesis,
                     outer membrane / General function prediction only];
                     Region: COG4948"
                     /db_xref="CDD:227284"
     misc_feature    complement(order(20725..20727,20800..20802,20881..20883,
                     20950..20952,21028..21030,21106..21108,21190..21192,
                     21196..21198))
                     /locus_tag="Smed_3592"
                     /note="active site pocket [active]"
                     /db_xref="CDD:239432"
     gene            complement(21747..22709)
                     /locus_tag="Smed_3593"
                     /db_xref="GeneID:5318973"
     CDS             complement(21747..22709)
                     /locus_tag="Smed_3593"
                     /note="PFAM: dihydrodipicolinate synthetase;
                     KEGG: sme:SMa0707 dihydrodipicolinate synthase, putative"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthetase"
                     /protein_id="YP_001312341.1"
                     /db_xref="GI:150375745"
                     /db_xref="InterPro:IPR002220"
                     /db_xref="GeneID:5318973"
                     /translation="MVHNINCKSHYTDLIMPLTGILPVLPTPFTESGVDIAAMRRIVR
                     FALDAGVAGVVFPGFASEVEMLTGEERLALLETVSAEVDGRVPVIAGASAATVDDVVA
                     YGRQALALGITQLMIQPPKSIGAGADAVAAFLSASAMQMPDAEFILQNAPAPRGSDLS
                     PEAVLKVVRRVPAVRYVKEETLPAGPAITAILADAPEHLLGVIGGGGARYILDEYDRG
                     ACAAMPALEIADLHVALDRNYRAGRGGEARTLYVKSLPLLALQAVYRMRLTKHVLGLR
                     GIIDNPIVRAPTPDLDAMAVRDIERCLQECEVESFGRSNRGSGA"
     misc_feature    complement(21801..22664)
                     /locus_tag="Smed_3593"
                     /note="Dihydrodipicolinate synthase/N-acetylneuraminate
                     lyase [Amino acid transport and metabolism / Cell envelope
                     biogenesis, outer membrane]; Region: DapA; COG0329"
                     /db_xref="CDD:223406"
     misc_feature    complement(21801..22649)
                     /locus_tag="Smed_3593"
                     /note="Dihydrodipicolinate synthase family; Region:
                     DHDPS-like; cd00408"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(22176..22178,22263..22265,22530..22538,
                     22545..22547,22638..22640))
                     /locus_tag="Smed_3593"
                     /note="inhibitor site; inhibition site"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(22041..22043,22176..22178,22263..22265,
                     22530..22538,22545..22547))
                     /locus_tag="Smed_3593"
                     /note="active site"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(21849..21854,22311..22313,22323..22325,
                     22344..22349,22419..22424,22515..22520,22533..22535))
                     /locus_tag="Smed_3593"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188630"
     misc_feature    complement(22176..22178)
                     /locus_tag="Smed_3593"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188630"
     gene            22728..23702
                     /locus_tag="Smed_3594"
                     /db_xref="GeneID:5318974"
     CDS             22728..23702
                     /locus_tag="Smed_3594"
                     /note="PFAM: 2-keto-3-deoxy-galactonokinase;
                     KEGG: sme:SMa0705 putative DgoK2
                     2-dehydro-3-deoxygalactonokinase"
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxy-galactonokinase"
                     /protein_id="YP_001312342.1"
                     /db_xref="GI:150375746"
                     /db_xref="InterPro:IPR007729"
                     /db_xref="GeneID:5318974"
                     /translation="MSIHITLKEMALPDAAYEPVTVVLDWGTTNFRAFLVKSDGSIVD
                     EKIGDRGIQSVTKGEHARVVSEGLASWRAEYGPLDIVAAGMIGSRNGWIEMPYVPTPA
                     AAGDLAAACRTIELAQGDRLTFLPGLTDLTAFPFPDVMRGEETQLVGFGLNRDMVIVL
                     PGTHAKWAEIKGGRIERFRTFVTGEIYATLASHSFLSKVATAERDHATAAFAEGIALA
                     QQECARAGGLLTRLFAVRTGWLAGTITPDEMKSRLSGLIVGWEFVEARAGGWFKEVDT
                     IAVVGDDDLVEVYERVATAFGLELAPAPADAAIRGALEISGRRSAAAT"
     misc_feature    22779..23696
                     /locus_tag="Smed_3594"
                     /note="2-keto-3-deoxy-galactonokinase [Carbohydrate
                     transport and metabolism]; Region: DgoK; COG3734"
                     /db_xref="CDD:226257"
     misc_feature    22800..23624
                     /locus_tag="Smed_3594"
                     /note="2-keto-3-deoxy-galactonokinase; Region: DGOK;
                     pfam05035"
                     /db_xref="CDD:218394"
     gene            23699..23884
                     /locus_tag="Smed_3595"
                     /db_xref="GeneID:5318975"
     CDS             23699..23884
                     /locus_tag="Smed_3595"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312343.1"
                     /db_xref="GI:150375747"
                     /db_xref="GeneID:5318975"
                     /translation="MKSGDLPTEPVTEIAVWTSGSLSGRRMGRRRQRRMKRATVAPAA
                     LAIATIMKPATYRHGCS"
     gene            23989..24162
                     /locus_tag="Smed_3596"
                     /pseudo
                     /db_xref="GeneID:5318976"
     gene            complement(24208..24987)
                     /locus_tag="Smed_3597"
                     /db_xref="GeneID:5318977"
     CDS             complement(24208..24987)
                     /locus_tag="Smed_3597"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR;
                     3-beta hydroxysteroid dehydrogenase/isomerase; KR domain
                     protein;
                     KEGG: sme:SMb20511 short chain dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="short chain dehydrogenase"
                     /protein_id="YP_001312344.1"
                     /db_xref="GI:150375748"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR002424"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5318977"
                     /translation="MSARLQGKRIMVTGAAQGIGLAIAEVFLSEGAALLLVDRDGPLL
                     EREASRLQEQGWELVYAQADITDAQAISVAVSSAATSIGRINALVNNAGINVFSEPLA
                     MSDADWQRCFDVNLRGAWNCCKAVLPNLIEQGGGAILNIASTHAFTIIPHTFPYPVAK
                     HALLGMTKALGIEYASKGVRVNALAPGYVLTQKAYDYWNSFPDPAAAEAATMKLHPGG
                     RIATAEEIARAAVFMISDECPFMNATCLTVDGGLSVLHHPA"
     misc_feature    complement(24214..24987)
                     /locus_tag="Smed_3597"
                     /note="short chain dehydrogenase; Provisional; Region:
                     PRK07063"
                     /db_xref="CDD:235924"
     misc_feature    complement(24241..24960)
                     /locus_tag="Smed_3597"
                     /note="classical (c) SDRs; Region: SDR_c; cd05233"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(24400..24402,24415..24417,24421..24432,
                     24508..24510,24520..24522,24559..24567,24646..24648,
                     24709..24717,24793..24801,24868..24876,24931..24942,
                     24946..24948))
                     /locus_tag="Smed_3597"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(24508..24510,24520..24522,24559..24561,
                     24643..24645))
                     /locus_tag="Smed_3597"
                     /note="active site"
                     /db_xref="CDD:212491"
     gene            complement(25022..26170)
                     /locus_tag="Smed_3598"
                     /db_xref="GeneID:5318432"
     CDS             complement(25022..26170)
                     /locus_tag="Smed_3598"
                     /note="PFAM: Mandelate racemase/muconate lactonizing
                     protein;
                     KEGG: sme:SMb20510 probable galactonate dehydratase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="YP_001312345.1"
                     /db_xref="GI:150375749"
                     /db_xref="InterPro:IPR001354"
                     /db_xref="InterPro:IPR013341"
                     /db_xref="InterPro:IPR013342"
                     /db_xref="GeneID:5318432"
                     /translation="MKITKLTTYIVPPRWLFLKIETDEGVVGWGEPVVEGRALTVEAA
                     VHELSDYLVGRDPFLIEDHWNVLYRGGFYRGGAIHMSALAGIDQALWDIKGKALGQPV
                     HSLLGGQCRDKIKVYSWIGGDRPSDVANNARDVVARGFKAIKLNGCEEMQIVDTNEKI
                     DRAVETIGTIRDAIGPNIGIGVDFHGRVHRPMAKVLAKELEQFKLMFIEEPVLSENRE
                     ALREIANHCSTPIALGERLYSRWDFKSVLSDGFVDIIQPDLSHAGGITECRKIAAMAE
                     AYDVALAPHCPLGPIALAACLQVDAVSYNAFIQEQSLGIHYNEANDILDYISNKDVFA
                     YEDGFVSIPQGPGLGIEVDEAYVMERAKEGHRWRNPVWRHSDGSVAEW"
     misc_feature    complement(25025..26170)
                     /locus_tag="Smed_3598"
                     /note="galactonate dehydratase; Provisional; Region:
                     PRK14017"
                     /db_xref="CDD:184455"
     misc_feature    complement(25112..26167)
                     /locus_tag="Smed_3598"
                     /note="D-galactonate dehydratase catalyses the dehydration
                     of galactonate to 2-keto-3-deoxygalactnate (KDGal), as
                     part of the D-galactonate nonphosphorolytic catabolic
                     Entner-Doudoroff pathway. D-galactonate dehydratase
                     belongs to the enolase superfamily of...; Region:
                     D-galactonate_dehydratase; cd03325"
                     /db_xref="CDD:239441"
     misc_feature    complement(order(25241..25243,25316..25318,25397..25399,
                     25466..25468,25544..25546,25550..25552,25622..25624,
                     25733..25735,25739..25741,25820..25822))
                     /locus_tag="Smed_3598"
                     /note="putative active site pocket [active]"
                     /db_xref="CDD:239441"
     misc_feature    complement(order(25466..25468,25544..25546,25622..25624))
                     /locus_tag="Smed_3598"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239441"
     gene            complement(26228..26983)
                     /locus_tag="Smed_3599"
                     /db_xref="GeneID:5318433"
     CDS             complement(26228..26983)
                     /locus_tag="Smed_3599"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20509 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312346.1"
                     /db_xref="GI:150375750"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318433"
                     /translation="MQGRHDQPTDSGSTPSRRPRVQKDVTRALAADICGENYPAGSYL
                     PRENDLCERYGVSRTVIRESLKILESKGLVRGRSRVGTVVCSKDEWNILDQQVLEWIG
                     DRIFQFDLLNCILEARRAIEPVAAELAARRATVQEIAEIERAWQQMRDAEGDLAKFTA
                     ADVAFHESLLKASHNQVFQQLASIIQAGLKFSLQASNEAADTRAGAVEIHRQLVEALR
                     MRDATAARDCSWQLLDLAARDLALAVERHSPPA"
     misc_feature    complement(26291..26944)
                     /locus_tag="Smed_3599"
                     /note="Transcriptional regulators [Transcription]; Region:
                     FadR; COG2186"
                     /db_xref="CDD:225097"
     misc_feature    complement(26729..26911)
                     /locus_tag="Smed_3599"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(26738..26749,26753..26758,26786..26788,
                     26795..26800,26804..26818,26840..26845,26849..26851))
                     /locus_tag="Smed_3599"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(26291..26644)
                     /locus_tag="Smed_3599"
                     /note="FCD domain; Region: FCD; pfam07729"
                     /db_xref="CDD:219539"
     gene            27191..28174
                     /locus_tag="Smed_3600"
                     /db_xref="GeneID:5318434"
     CDS             27191..28174
                     /locus_tag="Smed_3600"
                     /EC_number="3.6.3.17"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     KEGG: sme:SMb20508 putative ABC transporter periplasmic
                     sugar-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001312347.1"
                     /db_xref="GI:150375751"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318434"
                     /translation="MRFIKAFALAGTVAIFAATSAFASDVKIGFIVKQPEEPWFQDEW
                     KFADQAAKEKGFTLVKIGAQDGEKVQSAIDNLGAQGAQGFIICTPDVKLGPGIVAKAA
                     ANDLKLMTVDDRLVSADGSALEDVPHMGISATKIGEAAGEAIVAEIKKRGWDMKEVGA
                     IRVSYDQLPTAVDRVEGALSVLKANGFPEANIFDAPQAKTDTEAALNASTVVLNKNAG
                     IKKWVAVGLNDEAVLGAVRATETVGIPADSMIGVGIGGAESAINEFKKPSPTGFFGTV
                     IISPKRHGYETALNMYEWIANGKEPEKLILTAGQLALRDNYEAVRKDLGIE"
     sig_peptide     27191..27262
                     /locus_tag="Smed_3600"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 24"
     misc_feature    27269..28138
                     /locus_tag="Smed_3600"
                     /note="Periplasmic L-arabinose-binding protein (ABP), a
                     member of a family of pentose/hexose sugar-binding
                     proteins of the type I periplasmic binding protein
                     superfamily; Region: PBP1_arabinose_binding; cd01540"
                     /db_xref="CDD:107253"
     misc_feature    27269..28114
                     /locus_tag="Smed_3600"
                     /note="Periplasmic binding proteins and sugar binding
                     domain of LacI family; Region: Peripla_BP_1; pfam00532"
                     /db_xref="CDD:215977"
     misc_feature    order(27524..27526,27710..27712,27869..27874,27953..27955)
                     /locus_tag="Smed_3600"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107253"
     gene            28238..29764
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /db_xref="GeneID:5318435"
     CDS             28238..29764
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /EC_number="3.6.3.17"
                     /note="Part of the ABC transporter complex AraFGH involved
                     in the high affinity transport of arabinose"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose transporter ATP-binding protein"
                     /protein_id="YP_001312348.1"
                     /db_xref="GI:150375752"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318435"
                     /translation="MQDFLEFTSISKGYPGVQALSDVSFSVRKGAVHGLMGENGAGKS
                     TLIRVLSGDQAADTGEIRIDGRPQHYRSVRDAFDAGVIVIHQELQLVPELTVAENLWL
                     GRFPGRAGVIDRRQLIRVVGERLAEIGIDVDPGAKVASLSIGERQMVEIAKAVMLDAR
                     VIALDEPTSSLSSRESEILFSLIDRLRSNGTVILYVSHRLDEIFRLCDSLTVLRDGRL
                     AAHHPDVSKVTRDQIIAEMVGREISNIWGWRARPLGDARLTVEGVSGAALPHPISFTA
                     RSGEILGFFGLIGAGRSEMARLVYGADSRRQGTVLVDGVAVRADSPPHSIRAGIVLCP
                     EDRKFDGIVHGRSIEENMAISSRRHFSRFGILDRGKEAELAERFIARLRVRTPSRHQD
                     IVNLSGGNQQKVILGRWLSEEGVKVLLIDEPTRGIDVGAKSEIYEILYELAAQGMAIV
                     VISSELPEVMGIADRILVMCEGRIAAEIAREDFDEHRILTAALPDASATKAPISEQVR
                     "
     misc_feature    28238..29740
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /note="L-arabinose transporter ATP-binding protein;
                     Provisional; Region: araG; PRK11288"
                     /db_xref="CDD:183077"
     misc_feature    28250..28900
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    28346..28369
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(28355..28360,28364..28372,28493..28495,28730..28735,
                     28829..28831)
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    28484..28495
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(28517..28528,28670..28687)
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    28718..28735
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    28742..28753
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    28817..28837
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    28997..29659
                     /gene="araG"
                     /locus_tag="Smed_3601"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            29767..30720
                     /gene="araH"
                     /locus_tag="Smed_3602"
                     /db_xref="GeneID:5318436"
     CDS             29767..30720
                     /gene="araH"
                     /locus_tag="Smed_3602"
                     /EC_number="3.6.3.17"
                     /note="Part of the ABC transporter complex AraFGH involved
                     in the high affinity transport of arabinose"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose transporter permease"
                     /protein_id="YP_001312349.1"
                     /db_xref="GI:150375753"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318436"
                     /translation="MTTSLKKLLLGEQGLVVIFAAAFLVVSLTVPNFLTERNMLGLLQ
                     SVVTIGLVACTMMFCLASRDFDLSVGSTVAFSGMVAVMASNATGSIVLGLLAALACGT
                     AVGMANGVVIARFRINALITTLATMQIVRGFALIASDGRAVGINDPVFYQLSLSKFLS
                     VPTPIWVMAFFFVVFGFLLNRTVFGKNTLAIGGNPEASRLAGVDVARMRIWIFALQGL
                     VCAVAGILLASRITSGQPNAATGLELSVISACVLGGVSLAGGRATMTGVVVGVLIMGI
                     AENVMNLLNIQAFYQYVVRGLILLIAVLLDNLRSVAGRPRG"
     misc_feature    29878..30654
                     /gene="araH"
                     /locus_tag="Smed_3602"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    29902..30654
                     /gene="araH"
                     /locus_tag="Smed_3602"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    30352..30408
                     /gene="araH"
                     /locus_tag="Smed_3602"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            31108..32136
                     /locus_tag="Smed_3603"
                     /db_xref="GeneID:5318437"
     CDS             31108..32136
                     /locus_tag="Smed_3603"
                     /note="KEGG: sme:SMb20504 putative ABC transporter
                     periplasmic sugar-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter periplasmic
                     sugar-binding protein"
                     /protein_id="YP_001312350.1"
                     /db_xref="GI:150375754"
                     /db_xref="GeneID:5318437"
                     /translation="MRNFLSTTAMAVLATTLFSGAAAAAAENPFRCKPGEKYVMNVMV
                     SGVEYWFPVYEMFKQAGQQFGCETEYTGTPEYDVNKQIASFDQALAQNPAGILVHPMN
                     SDPFIEPINRATDQGTAVVTFAADSPLSKRVSYITSDNTREGIYAADKIAEKLGGKGE
                     YAVLENPGQDNHDKRIAAFIGRMEEKWPDMKLVGRAASNQDPNKAYQGLTSLIQANPN
                     LSAVFMPEANSAIGAAQANKETGGKVLVMCADVNANILDMIKAGEVFGSINPNQGMQG
                     YMGFLMLWLAKHPELIDPMNDAKRSGFNPMSIPVVDNGLSIVTAENADDFYWDKYLKR
                     RGTKGIEE"
     misc_feature    31108..32106
                     /locus_tag="Smed_3603"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     RbsB; COG1879"
                     /db_xref="CDD:224791"
     sig_peptide     31108..31182
                     /locus_tag="Smed_3603"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.680 at
                     residue 25"
     misc_feature    31216..31998
                     /locus_tag="Smed_3603"
                     /note="Periplasmic sugar-binding domain of active
                     transport systems that are members of the type I
                     periplasmic binding protein (PBP1) superfamily; Region:
                     PBP1_ABC_sugar_binding_like; cd01536"
                     /db_xref="CDD:107249"
     misc_feature    order(31252..31254,31477..31479,31630..31632,31855..31857,
                     31915..31917)
                     /locus_tag="Smed_3603"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107249"
     gene            32198..33739
                     /locus_tag="Smed_3604"
                     /db_xref="GeneID:5318438"
     CDS             32198..33739
                     /locus_tag="Smed_3604"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20503 putative sugar ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312351.1"
                     /db_xref="GI:150375755"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318438"
                     /translation="MTSETVLDIRNVSKHFGAVKALTAVNFRLERGEVHALCGENGAG
                     KSTLMNVIAGVLQPSEGEILVEGAPVRIASPAVAQSLGIGLVHQEIALCPDATIAENM
                     FMAATNRRRSVLMNYRKLERDAQILMNRLAPIDVRQKVGDLSISSQQLVEIAKALTLD
                     CRVLIFDEPTAALTETEAQVLFGIIRDLKARGISIIYISHRMAEVFSLCDRVTVFRDG
                     RYVATETVADITPDDVVRLMVGREIDQLYPEKHGQSGCVGEPILSVRKLGDGARFRDV
                     SFELRHGEILGVGGLIGSGRTEIAEGICALRAATQGEIRLHDKVLRLRRYSDAAKAGV
                     VYLSEDRKGSGIFLEMSIAQNIAALDLKALTSFGLLNFRKERSLAEELARRLGVRMGG
                     VDMPVSSLSGGNQQKVSIAKQLAVNPKVILLDEPTRGIDVGAKSEIHRLLRDLARAGI
                     GILVISSELPELIGLCDRVLVVREGGIAGEVSGDEMTEEAIMRLASGIGPEANTNSKA
                     SGHAA"
     misc_feature    32198..33688
                     /locus_tag="Smed_3604"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    32216..32866
                     /locus_tag="Smed_3604"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    32312..32335
                     /locus_tag="Smed_3604"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(32321..32326,32330..32338,32459..32461,32696..32701,
                     32795..32797)
                     /locus_tag="Smed_3604"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    32450..32461
                     /locus_tag="Smed_3604"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(32462..32464,32594..32611,32645..32653)
                     /locus_tag="Smed_3604"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    32684..32701
                     /locus_tag="Smed_3604"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    32708..32719
                     /locus_tag="Smed_3604"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    32783..32803
                     /locus_tag="Smed_3604"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    32969..33622
                     /locus_tag="Smed_3604"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            33759..34751
                     /locus_tag="Smed_3605"
                     /db_xref="GeneID:5318439"
     CDS             33759..34751
                     /locus_tag="Smed_3605"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20502 putative sugar ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001312352.1"
                     /db_xref="GI:150375756"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318439"
                     /translation="MAVDILPVAHDARRPAWKRIGTMREAGLIAIILSLCVIMSFASP
                     HFLTLGNFRAMLMSFSVEGIVVVGMTILLIVGGIDLSVGSVVCFSMVLSGSLFLMGVD
                     PWTASLVGIAASAAIGCIMGFFVTVVGLNHFITSLAAMVIVRGLCLVITKGTPLSLFT
                     LPPAFKAVGQGTFFGVPYVIVIFIAVVAVFDFLLRRATAFRKVFYTGSNEKAALYSGI
                     KTKDVKFWVTVLCTTLSGVAGTIYMARFGAATPTFGVGMELNIIAAAVIGGASLNGGS
                     GTILGAILGIALLSVVTSSLILLDVSVYWQDMIKGCILLAAVSIDHMLHKRKAA"
     misc_feature    33924..34568
                     /locus_tag="Smed_3605"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    33933..34721
                     /locus_tag="Smed_3605"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    34389..34445
                     /locus_tag="Smed_3605"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            34753..35757
                     /locus_tag="Smed_3606"
                     /db_xref="GeneID:5318440"
     CDS             34753..35757
                     /locus_tag="Smed_3606"
                     /note="PFAM: putative sugar-binding domain protein;
                     KEGG: sme:SMb20501 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="YP_001312353.1"
                     /db_xref="GI:150375757"
                     /db_xref="InterPro:IPR007324"
                     /db_xref="GeneID:5318440"
                     /translation="MPNAKPKSTSGPREEIVIARQMHQALVLHFLEGLTQAQIADQLG
                     ISHATVNRLIKRGRQLGLVEIKIKSPVEPLIDIEERLLALGGISRAVVVPTASDNPQT
                     ALQAVGEAAARLMLEEIADGDTICITGGKGVSAVVAGLHPPRRYDIEVIPATGCVQGK
                     HYTDVNHVSTLMADRLGGHSFQIHAPLFADSEAERRMLLGMRAVADVFKQAREAKIAV
                     VGIGSILSDDSSYYDLHPSSSTDRAAIEQSGASCELLAHLLDDQGRVCGYGLNQRLVS
                     LTLSEFASIPMKIGVASGPSKAGPILSVMRGKHLDTLVTDQATGSRILELAKEVGEHS
                     "
     misc_feature    34786..35736
                     /locus_tag="Smed_3606"
                     /note="Transcriptional regulator, contains sigma
                     factor-related N-terminal domain [Transcription]; Region:
                     DeoR; COG2390"
                     /db_xref="CDD:225263"
     misc_feature    <34822..34929
                     /locus_tag="Smed_3606"
                     /note="Sigma70, region (SR) 4 refers to the most
                     C-terminal of four conserved domains found in Escherichia
                     coli (Ec) sigma70, the main housekeeping sigma, and
                     related sigma-factors (SFs). A SF is a dissociable subunit
                     of RNA polymerase, it directs bacterial or...; Region:
                     Sigma70_r4; cd06171"
                     /db_xref="CDD:100119"
     misc_feature    order(34837..34839,34855..34860,34888..34890,34894..34899,
                     34903..34911,34915..34920,34924..34926)
                     /locus_tag="Smed_3606"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:100119"
     misc_feature    34957..35727
                     /locus_tag="Smed_3606"
                     /note="Putative sugar-binding domain; Region: Sugar-bind;
                     pfam04198"
                     /db_xref="CDD:217959"
     gene            35754..36749
                     /locus_tag="Smed_3607"
                     /db_xref="GeneID:5318618"
     CDS             35754..36749
                     /locus_tag="Smed_3607"
                     /note="PFAM: aldo/keto reductase;
                     KEGG: sme:SMb20500 putative aldoketo reductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="YP_001312354.1"
                     /db_xref="GI:150375758"
                     /db_xref="InterPro:IPR001395"
                     /db_xref="GeneID:5318618"
                     /translation="MNGQQMTRMIGRSGIAASPVGLGTWAIGGWMWGGTDERESVAAI
                     QASLDAGVTLIDTAPAYGLGRAEEIVGKALVGRRDKAVIATKCGLVWHTRQGNHFFDQ
                     DGKPVHRHLGRESIFHEVEQSLKRLGTDYIDLYITHWQDPTTPIEETMQALEELRAAG
                     KIRAIGASNVNLEELEIYVKIGGLDAIQERYSMLDREIEGNLLPVTTANGVATLSYSS
                     LALGLLSGRIGPERVFSGDDQRKANPRFSASNREKIMRFAETIRPVAQKHEATIAQIV
                     IAWTLAQPGITFALCGARNPAQARDNARAGTIRLNADDLSAIDAARAAALVNMDR"
     misc_feature    35772..36683
                     /locus_tag="Smed_3607"
                     /note="Aldo-keto reductases (AKRs) are a superfamily of
                     soluble NAD(P)(H) oxidoreductases whose chief purpose is
                     to reduce aldehydes and ketones to primary and secondary
                     alcohols. AKRs are present in all phyla and are of
                     importance to both health and industrial...; Region:
                     Aldo_ket_red; cd06660"
                     /db_xref="CDD:119408"
     misc_feature    35808..36686
                     /locus_tag="Smed_3607"
                     /note="Aldo/keto reductase family; Region: Aldo_ket_red;
                     pfam00248"
                     /db_xref="CDD:215817"
     misc_feature    order(35820..35828,35919..35921,35934..35936,36009..36011,
                     36165..36170,36255..36260,36315..36317,36399..36416,
                     36570..36572,36621..36632,36645..36647,36654..36659)
                     /locus_tag="Smed_3607"
                     /note="active site"
                     /db_xref="CDD:119408"
     misc_feature    order(35919..35921,35934..35936,36009..36011,36165..36167)
                     /locus_tag="Smed_3607"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:119408"
     gene            36806..38494
                     /locus_tag="Smed_3608"
                     /db_xref="GeneID:5318619"
     CDS             36806..38494
                     /locus_tag="Smed_3608"
                     /note="PFAM: FAD dependent oxidoreductase;
                     KEGG: sme:SMb20499 putative glycerol-3-phosphate
                     dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD dependent oxidoreductase"
                     /protein_id="YP_001312355.1"
                     /db_xref="GI:150375759"
                     /db_xref="InterPro:IPR000447"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="GeneID:5318619"
                     /translation="MDVCVLGGGINGLSVFRELALQGLRVLLIEKHDYCSGASAALSR
                     MVHGGLRYLENGEFTLVKESLVERDRLLRNAPHLVAPLATTVPIFDVFSGLANGIVRF
                     LGLSRRPSRRGAIAIKAGLSIYDLLTRKRALMPRHRFRGRRSTLAKWPALNPTIRSSA
                     TYYDAWVRHPERIGMELLQDGLSASSEAAALNYAELRRSESGGFLVVDTIDGAGVEIK
                     PGLIVNSTGGWIDITNGALLPPDNGCGPLVGGTKGSHLVIDNPQLREALGDHMIYYEN
                     EDGRICILFPYFGKVLVGSTDIRVDDPETVRCEEEERDYILQSLAFVLPGIEIAPTEI
                     VFQFSGVRPLPASSDNFTGRIPRDHFCTTIENAGTPVLCMIGGKWTTFRSFGELAANM
                     ALERLGRPRHVSTADRAIGGGRHFPADRDSWISALALRFGLPRTQAAELFSRYGTDAE
                     PVASFIGQASDAVIPGADYSTREVLFLIRNEAVEHLDDLLLRRTTLAVSGALSLGILD
                     AALELLAEEKGWSTARRLSERARCLALLLERHGIDEQTLGARTHQPGDKAMAAG"
     misc_feature    36809..38368
                     /locus_tag="Smed_3608"
                     /note="Glycerol-3-phosphate dehydrogenase [Energy
                     production and conversion]; Region: GlpA; COG0578"
                     /db_xref="CDD:223651"
     misc_feature    36818..>36916
                     /locus_tag="Smed_3608"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; pfam13450"
                     /db_xref="CDD:205628"
     gene            38561..39403
                     /locus_tag="Smed_3609"
                     /db_xref="GeneID:5318620"
     CDS             38561..39403
                     /locus_tag="Smed_3609"
                     /note="PFAM: deoxyribose-phosphate
                     aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase;
                     KEGG: sme:SMb20498 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate
                     aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase"
                     /protein_id="YP_001312356.1"
                     /db_xref="GI:150375760"
                     /db_xref="InterPro:IPR002915"
                     /db_xref="GeneID:5318620"
                     /translation="MKSNRKVRMNRMFNGGRCLDVAIDHGVCNEPSFLSGLENMEAVV
                     SALVEAGPDAIQMNFGQADLLQELPGKDRPALVMRLDMGNPYNRLRHRDMWAVLQNEA
                     EPLIGALAMDAACVVVNLFMLPDEPDLFRQCVQNIARVRADCDTYGMPLMIEPLVMQP
                     VTEHGGYMVDGDAEKIVTLTRLAREMGADIIKADPTTHAEDFHRVVETARCPVLVRGG
                     GKEDLRSVFDKSSALMNQGAMGMVYGRNIYQHPDPKAVVRGLMAIVHENASGEEAFSL
                     YRQG"
     misc_feature    38561..39376
                     /locus_tag="Smed_3609"
                     /note="DhnA-type fructose-1,6-bisphosphate aldolase and
                     related enzymes [Carbohydrate transport and metabolism];
                     Region: FbaB; COG1830"
                     /db_xref="CDD:224743"
     misc_feature    38612..39355
                     /locus_tag="Smed_3609"
                     /note="Class I fructose-1,6-bisphosphate (FBP) aldolases
                     of the archaeal type (DhnA homologs); Region: DhnA;
                     cd00958"
                     /db_xref="CDD:188645"
     misc_feature    order(39182..39184,39191..39193,39254..39262,39320..39328)
                     /locus_tag="Smed_3609"
                     /note="putative active site; other site"
                     /db_xref="CDD:188645"
     misc_feature    39182..39184
                     /locus_tag="Smed_3609"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188645"
     gene            39434..40963
                     /locus_tag="Smed_3610"
                     /db_xref="GeneID:5318621"
     CDS             39434..40963
                     /locus_tag="Smed_3610"
                     /note="PFAM: carbohydrate kinase FGGY;
                     KEGG: sme:SMb20497 putative L-xylulose kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase FGGY"
                     /protein_id="YP_001312357.1"
                     /db_xref="GI:150375761"
                     /db_xref="InterPro:IPR000577"
                     /db_xref="GeneID:5318621"
                     /translation="MGRYLLGLDAGNTVIKAVIFDREGSEIASAAAEGHSRMPSPGHV
                     ERGLDELWQNARRVIRTCIDEAEIDAGEIGAIGCAGHGNGLYALDRDGRPLLAIQSLD
                     TRAAALVDEWKSQGVGERTYPIGRQRPWPSQTPTLLAWLKRHRPEVFASLGTVFLCKD
                     FIVNRLTGARVSDVSDMTGCGLLNLAGRHYDAALMAAYGLSDSMDLLPPLVESADIAG
                     RLTEAAAAETGLAAGTPVVGGLFDVVASAIGSGVTRTGAASIIAGTWSINQVIIEGPE
                     LDGPVFMSSTFDRDRYMAIESSATSAANLEWLVREFFSDIRCEGRSPFDLCCELASSS
                     EPASDDPLYHPFLYGAQQDGSARAGFYGIAGWHTKGHLVRAVLEGVAFGHRQHIEAIR
                     KAGADFDEAILSGGGSRSLVWPQIFADVLGVPVSVARSRETGALGAAIAAGTGVGIFS
                     DFAEGAAAMVKTDRHYRPNTAREPHYARRYALYRDIADAMAPLWRRLSAIEATTAGAA
                     A"
     misc_feature    39434..40927
                     /locus_tag="Smed_3610"
                     /note="Sugar (pentulose and hexulose) kinases
                     [Carbohydrate transport and metabolism]; Region: XylB;
                     COG1070"
                     /db_xref="CDD:223996"
     misc_feature    39443..40729
                     /locus_tag="Smed_3610"
                     /note="L-xylulose kinases; a subfamily of the FGGY family
                     of carbohydrate kinases; Region: FGGY_L-XK; cd07802"
                     /db_xref="CDD:212666"
     misc_feature    order(39443..39460,39464..39472,39479..39481,39485..39487,
                     39491..39496,39503..39511,39518..39520,39653..39676,
                     39731..39733,39749..39751,39827..39832,39950..39958,
                     39965..39967,39980..39982,39986..39988,39995..39997,
                     40067..40072,40076..40081,40136..40147,40157..40168,
                     40223..40225,40232..40234,40265..40273,40283..40294,
                     40295..40297,40310..40312,40319..40321,40325..40327,
                     40349..40351)
                     /locus_tag="Smed_3610"
                     /note="putative N- and C-terminal domain interface
                     [polypeptide binding]; other site"
                     /db_xref="CDD:212666"
     misc_feature    order(39458..39460,39464..39475,39479..39481,39674..39676,
                     39680..39682,39731..39733,40157..40162,40217..40225,
                     40232..40234,40337..40339,40349..40351,40400..40402,
                     40649..40657,40661..40663)
                     /locus_tag="Smed_3610"
                     /note="putative active site [active]"
                     /db_xref="CDD:212666"
     misc_feature    order(39458..39460,39464..39475,39479..39481,40157..40159,
                     40217..40225,40337..40342,40346..40351,40400..40405,
                     40409..40411,40649..40657,40661..40663)
                     /locus_tag="Smed_3610"
                     /note="MgATP binding site [chemical binding]; other site"
                     /db_xref="CDD:212666"
     misc_feature    order(39458..39460,39467..39469,40157..40159)
                     /locus_tag="Smed_3610"
                     /note="catalytic site [active]"
                     /db_xref="CDD:212666"
     misc_feature    order(39458..39460,40157..40159)
                     /locus_tag="Smed_3610"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:212666"
     misc_feature    order(39674..39676,39680..39682,39731..39733,40157..40162,
                     40319..40321)
                     /locus_tag="Smed_3610"
                     /note="putative xylulose binding site [chemical binding];
                     other site"
                     /db_xref="CDD:212666"
     gene            40960..42564
                     /locus_tag="Smed_3611"
                     /db_xref="GeneID:5318622"
     CDS             40960..42564
                     /locus_tag="Smed_3611"
                     /note="PFAM: glucose-methanol-choline oxidoreductase; GMC
                     oxidoreductase;
                     KEGG: sme:SMb20496 probable GMC oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-methanol-choline oxidoreductase"
                     /protein_id="YP_001312358.1"
                     /db_xref="GI:150375762"
                     /db_xref="InterPro:IPR000172"
                     /db_xref="InterPro:IPR007867"
                     /db_xref="GeneID:5318622"
                     /translation="MNPHPNETYDFIVVGAGSAGCVLANRLSADPRNRVLLLEAGGSD
                     RYHWVHVPIGYLYCMGNPRTDWMMRTAAEPGLNGRSLPYPRGKLLGGCSSINGMIYMR
                     GQAADYDGWRQAGNAGWGWDDVLPYFLKSEDNHRGTSAMHGAGGEWRVERQRLSWPIL
                     DAFRDAAEELGIPKTEDFNIGDNEGSGYFEVNQRGGVRWNTTKAFLRPAMKRPNLKVL
                     TGAETERLIFEGRRTKGIRFRLHGRIREARATREVILSAGAINTPKILELSGVGRPDV
                     VSAAGIELVHDLPGVGENLQDHLQIRTVFRIEGAKTLNQLYHSVFSRMGMGLEYMLRR
                     SGPLSMAPSQLGIFARSSPSVATADLEYHVQPLSTDRLGEPLHKHPAVTVSVCNLRPE
                     SRGSVHVTTGDASAAPDIRPNYLSTAGDRLLAAQAIRHARSLMATKAIARFKPAEMLP
                     GAEFQSEDELIRRAGDIATTIFHPVGTCKMGSDPMAVVDPSLKVHGLDGLRVVDASIM
                     PSIVSGNTNSPVIMIAEKAADAILRR"
     misc_feature    40975..42561
                     /locus_tag="Smed_3611"
                     /note="choline dehydrogenase; Validated; Region: PRK02106"
                     /db_xref="CDD:235000"
     misc_feature    42130..42540
                     /locus_tag="Smed_3611"
                     /note="GMC oxidoreductase; Region: GMC_oxred_C; pfam05199"
                     /db_xref="CDD:218493"
     gene            43270..46539
                     /locus_tag="Smed_3612"
                     /db_xref="GeneID:5318623"
     CDS             43270..46539
                     /locus_tag="Smed_3612"
                     /note="PFAM: adenylyl cyclase class-3/4/guanylyl cyclase;
                     TPR repeat-containing protein; Tetratricopeptide TPR_2
                     repeat protein;
                     SMART: Tetratricopeptide domain protein;
                     KEGG: bja:bll5958 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl cyclase class-3/4/guanylyl cyclase"
                     /protein_id="YP_001312359.1"
                     /db_xref="GI:150375763"
                     /db_xref="InterPro:IPR001054"
                     /db_xref="InterPro:IPR001440"
                     /db_xref="InterPro:IPR013026"
                     /db_xref="InterPro:IPR013105"
                     /db_xref="GeneID:5318623"
                     /translation="MNCAGCGLEIQGGFAFCPKCGMRQPKSCLGCGYPCPSDSAFCPK
                     CGAPTNDAGAEGKPTSRAASALTVKIKQPALPAVDADRRTITILFADLSGFTALSEQI
                     DPELMQALQNELFEELTEAVQSFGGFVDKFIGDALLALFGAPIAHEEDPERALRAALD
                     MVERASRMGERWQARAGAPPILHIGVNTGPVVTGGFGAGSAKSYSVTGDTVNTAQRLQ
                     SMASPSEVLVGPLTQRLTRHAFVFETLGETMLRGKTGSIPVYRLKGLREAARPARGLE
                     ALGLSTPLIGRKAELERMFASLDLACRGSAQLVRLVGEAGIGKSRLVNEFIARIGDEQ
                     RFAAVAIRQAACSPLGEQSYGTLAAVVRSAAGMRQGGPVAETKARLSDLLGELGLNGD
                     EAVSLTPLLLHVVGLGGPEGALRHVQPEQLRRQIFFAIRTIFERRLALGPLLIVVEDL
                     HWADAVSLEALRFLMDRLEQQRLIMVFTHRPTFDMEQLDSRRISHTTLRLAPLDDNGG
                     RKLLASLFGEKWDQTLNSLGSRILDRAGGNPLFIEEIVRGFIEDGILERDGLHWRAAS
                     SEAAVEIPASIQAILLARADRLPPEARRLAQEAAVLGPRFDATLLAAISAHPKNIETG
                     LDILCDAEIIEEVAAGGSIASRSYRFTQALLQNVIYQNLLLQRRTEMHGQVGMALEQS
                     CGQDPERLEDLLLLGHHFSLSPNRAKGARYLRSAGDRARAVYANDDAIRHYQQALTAL
                     ADEPEPVELRLSLRERIADLCGTTGRREAAHEHYRTVLVARRATGDRAGAARILRKLG
                     RLLWQAGKRTHAEAHYAEAALLLEGTDARIEQALLLQERGRLAFRIGEHSNAIKWAEK
                     ALEQAESLPVDADEGTRLEAAHATAEALNTKGVALARLERCREAVIEVEQSVNVAEAA
                     GLLSAACRGYTNLGVLYTVIDPARAIQVCRRGLEVARRIGDLGFQARLLANLAVVSCT
                     FTDRCGGEGVPAAEKAIELDRALDQREHLPVPLIVLGQIHQCHGEPELAARCYNEALE
                     VARETGEPQMLFPCYDGLATLSLDVGDMGEAERYFSLAQDVCNQHGLDPEGLVVLPFL
                     D"
     misc_feature    43276..43407
                     /locus_tag="Smed_3612"
                     /note="Double zinc ribbon; Region: DZR; pfam12773"
                     /db_xref="CDD:221766"
     misc_feature    43339..43413
                     /locus_tag="Smed_3612"
                     /note="zinc-ribbon domain; Region: zf-ribbon_3; pfam13248"
                     /db_xref="CDD:205428"
     misc_feature    43492..44091
                     /locus_tag="Smed_3612"
                     /note="Adenylate cyclase, family 3 (some proteins contain
                     HAMP domain) [Signal transduction mechanisms]; Region:
                     CyaA; COG2114"
                     /db_xref="CDD:225025"
     misc_feature    43519..44055
                     /locus_tag="Smed_3612"
                     /note="cyclase homology domain; Region: CHD; cd07302"
                     /db_xref="CDD:143636"
     misc_feature    order(43534..43536,43540..43557,43660..43662,43666..43674,
                     43681..43683,43882..43890,43900..43905,43912..43917,
                     44020..44022)
                     /locus_tag="Smed_3612"
                     /note="nucleotidyl binding site; other site"
                     /db_xref="CDD:143636"
     misc_feature    order(43540..43542,43672..43674)
                     /locus_tag="Smed_3612"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143636"
     misc_feature    order(43555..43557,43591..43593,43600..43605,43612..43614,
                     43624..43626,43660..43665,43843..43845,43852..43854,
                     43885..43896,43903..43905,44020..44022)
                     /locus_tag="Smed_3612"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143636"
     misc_feature    44116..>45861
                     /locus_tag="Smed_3612"
                     /note="Predicted ATPase [General function prediction
                     only]; Region: COG3899"
                     /db_xref="CDD:226415"
     misc_feature    44116..44697
                     /locus_tag="Smed_3612"
                     /note="AAA ATPase domain; Region: AAA_16; pfam13191"
                     /db_xref="CDD:221970"
     misc_feature    45748..46008
                     /locus_tag="Smed_3612"
                     /note="Tetratricopeptide repeat; Region: TPR_12;
                     pfam13424"
                     /db_xref="CDD:205602"
     misc_feature    46225..46485
                     /locus_tag="Smed_3612"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cd00189"
                     /db_xref="CDD:238112"
     misc_feature    order(46231..46233,46240..46242,46249..46251,46294..46296,
                     46330..46332,46342..46344,46351..46353,46414..46416,
                     46450..46452,46462..46464,46471..46473)
                     /locus_tag="Smed_3612"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     misc_feature    order(46285..46290,46294..46299,46306..46311,46405..46410,
                     46417..46422,46429..46434)
                     /locus_tag="Smed_3612"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     gene            complement(46975..47631)
                     /locus_tag="Smed_3613"
                     /db_xref="GeneID:5318624"
     CDS             complement(46975..47631)
                     /locus_tag="Smed_3613"
                     /note="PFAM: alkyl hydroperoxide reductase/ Thiol specific
                     antioxidant/ Mal allergen; Redoxin domain protein;
                     KEGG: ret:RHE_CH01008 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase"
                     /protein_id="YP_001312360.1"
                     /db_xref="GI:150375764"
                     /db_xref="InterPro:IPR000866"
                     /db_xref="InterPro:IPR011767"
                     /db_xref="InterPro:IPR013740"
                     /db_xref="GeneID:5318624"
                     /translation="MSITQISQPVTPGEPAPDFVLPAVDGSGTISLADYRGRTPLFLA
                     LFIGLWCPFCRRAIAQIAASESALKSAGVETLGVVATAPDNAQLYFRFRPTRLRLAAD
                     PELSTHQAYGVPRPIPTPEFLRALDTTLINPDGLFAEPLPITHAAEAIGKLDNYKYNE
                     TDQADMERQWPQLKGQFLIDRAGFVRWAYIECAADGLAGLGKFPSATEVLAAARALAD
                     "
     misc_feature    complement(47059..47589)
                     /locus_tag="Smed_3613"
                     /note="Peroxiredoxin (PRX)-like 2 family; hypothetical
                     proteins that show sequence similarity to PRXs. Members of
                     this group contain a CXXC motif, similar to TRX. The
                     second cysteine in the motif corresponds to the
                     peroxidatic cysteine of PRX, however, these...; Region:
                     PRX_like2; cd02970"
                     /db_xref="CDD:239268"
     misc_feature    complement(order(47470..47472,47479..47481))
                     /locus_tag="Smed_3613"
                     /note="putative catalytic residues [active]"
                     /db_xref="CDD:239268"
     gene            48651..49637
                     /locus_tag="Smed_3614"
                     /db_xref="GeneID:5318625"
     CDS             48651..49637
                     /locus_tag="Smed_3614"
                     /EC_number="1.6.99.5"
                     /note="PFAM: respiratory-chain NADH dehydrogenase subunit
                     1;
                     KEGG: sme:SMa1516 NADH dehydrogenase I chain H"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase (quinone)"
                     /protein_id="YP_001312361.1"
                     /db_xref="GI:150375765"
                     /db_xref="InterPro:IPR001694"
                     /db_xref="InterPro:IPR010916"
                     /db_xref="GeneID:5318625"
                     /translation="MELVVALGLIVFKVALLIAILLLLPLPLTWLERKIAGHMQQRMG
                     PMRVGWHGLLQPVADGIKLLTKEDHIPAEADRFLFKLAPILALAPPFVVFAAIPFGET
                     VSVLGNEITLYISNLNVALLFVFAVIGLEVYGVIFGGWAANSKYAVLGSLRTCAQMIS
                     YEIPMGFAVIGVVMLAQSMSLLDIVRAQSDVWNVVYQPIGFFVFFVAGLAEAQRIPFD
                     LAEAEGDLGAGFHTEYSGIRFALFMVSEYVVMVLVSVLTVILFFGGWNGVLIPLPPLL
                     WFLLKVAFFIYLFMWFRFTFPRYRYDQLMAIGWKVLLPLSLANIIISGVVFS"
     misc_feature    48735..49628
                     /locus_tag="Smed_3614"
                     /note="NADH:ubiquinone oxidoreductase subunit H;
                     Provisional; Region: PRK06076"
                     /db_xref="CDD:235692"
     misc_feature    48741..49613
                     /locus_tag="Smed_3614"
                     /note="Formate hydrogenlyase subunit 4 [Energy production
                     and conversion]; Region: HyfC; COG0650"
                     /db_xref="CDD:223723"
     gene            49637..50272
                     /locus_tag="Smed_3615"
                     /db_xref="GeneID:5318626"
     CDS             49637..50272
                     /locus_tag="Smed_3615"
                     /note="TIGRFAM: NADH-quinone oxidoreductase, chain I;
                     PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain
                     protein;
                     KEGG: sme:SMa1519 putative oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit I"
                     /protein_id="YP_001312362.1"
                     /db_xref="GI:150375766"
                     /db_xref="InterPro:IPR001450"
                     /db_xref="InterPro:IPR010226"
                     /db_xref="GeneID:5318626"
                     /translation="MHAAQKLWVRTCKKTLRSRSEAAMSHALDKAGRWIGWAFFADLA
                     NGLALTFGYMFSKPVTMQYPDKEKWLPYSRYRGHHFLKRDAEGEIKCVACELCAQICP
                     CDCIEVVPYEDEKGNRRPAKFEIDTARCLFCGLCEDACPADAIALGQQYEFSSFSSRD
                     LVIGRDDLLAKPGKAMTGGGVVAARLSTERDVLVEASEPRGYNWWRNIRRK"
     misc_feature    49772..50140
                     /locus_tag="Smed_3615"
                     /note="NADH-quinone oxidoreductase, chain I; Region: NuoI;
                     TIGR01971"
                     /db_xref="CDD:233661"
     misc_feature    50003..50071
                     /locus_tag="Smed_3615"
                     /note="4Fe-4S binding domain; Region: Fer4; pfam00037"
                     /db_xref="CDD:215671"
     gene            50315..50755
                     /locus_tag="Smed_3616"
                     /db_xref="GeneID:5318627"
     CDS             50315..50755
                     /locus_tag="Smed_3616"
                     /note="PFAM: CBS domain containing protein;
                     KEGG: sme:SMa1521 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="signal-transduction protein"
                     /protein_id="YP_001312363.1"
                     /db_xref="GI:150375767"
                     /db_xref="InterPro:IPR000644"
                     /db_xref="GeneID:5318627"
                     /translation="MHICQILRSKSPEIFSVTPDHTMVEVLQLFRDRNIGFVVVGRSP
                     GECLGTLSERDCCYAVAEYGSEAPLMRVGEIMNRTVATCSTEDFLPFVMSIMTERRTR
                     HVLVMDGNDAVGVVSIGDVVKHRLEEALQAERDMHDYICGANYR"
     misc_feature    50342..50680
                     /locus_tag="Smed_3616"
                     /note="FOG: CBS domain [General function prediction only];
                     Region: COG0517"
                     /db_xref="CDD:223591"
     misc_feature    50348..50686
                     /locus_tag="Smed_3616"
                     /note="The CBS domain, named after human CBS, is a small
                     domain originally identified in cystathionine
                     beta-synthase and is subsequently found in a wide range of
                     different proteins. CBS domains usually occur in tandem
                     repeats. They associate to form a so-called...; Region:
                     CBS_pair_10; cd04623"
                     /db_xref="CDD:239995"
     gene            complement(50839..53391)
                     /locus_tag="Smed_3617"
                     /db_xref="GeneID:5318148"
     CDS             complement(50839..53391)
                     /locus_tag="Smed_3617"
                     /note="PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur
                     binding domain protein; molybdopterin oxidoreductase;
                     molydopterin dinucleotide-binding region; molybdopterin
                     oxidoreductase Fe4S4 region;
                     KEGG: sme:SMa1523 NADH dehydrogenase I chain G"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin oxidoreductase"
                     /protein_id="YP_001312364.1"
                     /db_xref="GI:150375768"
                     /db_xref="InterPro:IPR000283"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR001450"
                     /db_xref="InterPro:IPR006655"
                     /db_xref="InterPro:IPR006656"
                     /db_xref="InterPro:IPR006657"
                     /db_xref="InterPro:IPR006963"
                     /db_xref="GeneID:5318148"
                     /translation="MVKVTIDEQTLEVEAGSTVLAAAERLGIEIPTFCYWKRLPPLAS
                     CRMCLVEIEGLRRLQPACATVAADGMAVRTNTPLIEETRASMLDMLLANHPLDCPICD
                     KGGECELQDMVMAYGPGESRFRDPKRVFHSKDIRLSPVIIMNVNRCIQCQRCVRMCEE
                     VVGAVALGTVEKGMDTAVTGFEGSLASCDQCGNCVEVCPVGALMSFPYRYRARPWDLA
                     ETDTICPHCGTGCQLTVGARKGEFMRVRSDWEHGVNRETLCVRGRFGLDFIEGRDRIK
                     RPMIRRDGALTPVSWEEAGEFLRQRLAAVEGRAAGGLISPRLPNEVLYQFQKLMRTVF
                     RTNNVDCSSRWSTPLDILAPLVASFYSRGALEQVIGNDCVLVVGGNVTEENPVTEYLL
                     RDAARRRDTGLLMLSARPSRLDADARAVLRVQPGGEAQGLAAVVAALAAVADEGLPGD
                     IPAKTPSSAAGANDALDRLVVMLKEGRNVTVLANVDLLRSPLARETLQQLGNLLQLLR
                     LLGKEPSMQFLFDRANQMGAWDMGVLPGVLPGLGPVADEATRTKFERSWGAEIPRKPG
                     ADVDAMLELCENGRMGVLYVVGSDPMMSYPDREFVERALGAASLLIVQEAFFTDTAGL
                     ADVVLPAAGYGEESGTFTNNEGRIQALRKFREPPFDARSNLAIFDFIAALREQPLQLS
                     ASAAVFDEITRLVSAYEGLTWEGLGGDGAFTRSAPRPWAGAPFAPPPPTRVTDVLQLI
                     TGNCLFHNGYVSERSQTLNSVADDPFIEMSARDAARLSLSDGDQVLVRSARGELTAKL
                     KVNKRFPDGLVFVPENYRALRLNSLMRRGEYPCPVEIRACAKAASALEEDRV"
     misc_feature    complement(50872..53391)
                     /locus_tag="Smed_3617"
                     /note="Uncharacterized anaerobic dehydrogenase [General
                     function prediction only]; Region: COG3383"
                     /db_xref="CDD:225918"
     misc_feature    complement(53173..53388)
                     /locus_tag="Smed_3617"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(53206..53211,53248..53259,53263..53265,
                     53290..53292,53299..53304))
                     /locus_tag="Smed_3617"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(53206..53208,53248..53250,53257..53259,
                     53290..53292))
                     /locus_tag="Smed_3617"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     misc_feature    complement(53023..53145)
                     /locus_tag="Smed_3617"
                     /note="NADH-ubiquinone oxidoreductase-G iron-sulfur
                     binding region; Region: NADH-G_4Fe-4S_3; pfam10588"
                     /db_xref="CDD:204520"
     misc_feature    complement(52783..>52830)
                     /locus_tag="Smed_3617"
                     /note="4Fe-4S binding domain; Region: Fer4; pfam00037"
                     /db_xref="CDD:215671"
     misc_feature    complement(51247..52731)
                     /locus_tag="Smed_3617"
                     /note="MopB_NDH-1_NuoG2-N7: The second domain of the NuoG
                     subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone
                     oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in
                     various bacteria. The NDH-1 is the first
                     energy-transducting complex in the respiratory...; Region:
                     MopB_NDH-1_NuoG2-N7; cd02771"
                     /db_xref="CDD:239172"
     misc_feature    complement(order(52615..52617,52699..52701,52711..52713,
                     52720..52722))
                     /locus_tag="Smed_3617"
                     /note="[4Fe-4S] binding site [ion binding]; other site"
                     /db_xref="CDD:239172"
     misc_feature    complement(<50956..51177)
                     /locus_tag="Smed_3617"
                     /note="Molybdopterin-Binding, C-terminal (MopB_CT) domain
                     of the MopB superfamily of proteins, a  large, diverse,
                     heterogeneous superfamily of enzymes that, in general,
                     bind molybdopterin as a cofactor. The MopB domain is found
                     in a wide variety of molybdenum-...; Region: MopB_CT;
                     cl09929"
                     /db_xref="CDD:245204"
     gene            complement(53420..54685)
                     /locus_tag="Smed_3618"
                     /db_xref="GeneID:5318149"
     CDS             complement(53420..54685)
                     /locus_tag="Smed_3618"
                     /EC_number="1.6.99.5"
                     /note="TIGRFAM: NADH-quinone oxidoreductase, F subunit;
                     PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa
                     subunit;
                     KEGG: sme:SMa1525 NADH dehydrogenase I chain F"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit F"
                     /protein_id="YP_001312365.1"
                     /db_xref="GI:150375769"
                     /db_xref="InterPro:IPR001949"
                     /db_xref="InterPro:IPR011537"
                     /db_xref="InterPro:IPR011538"
                     /db_xref="GeneID:5318149"
                     /translation="MFEPVLLRNVDVPDGHLLSTYQVGGGYQALTKALGEYTPDEIVE
                     LVKESNLRGRGGAGFPTGMKWSFVPKAAGKPKYLCCNADEGEPGTFKDRIIMERDPHQ
                     LIEGLAVSAYAIGAETAYVYIRGEYVTAIRRMEQAIAQAHENGYLGTGILGSNFKFMV
                     HIHRGAGAYICGEETAMLESLEGKRAQPRLKPPFPAVAGLYASPTVINNVETLACVPH
                     IVMRGSAWFRGIGPDRSPGPKLYCVSGQVRKPGLYELPMGISLRELVEEYAGGPLPGR
                     KVKAVIPGGVSAPVIPESDLEVGMDFDSLAAAGSMLGSAGVVVIDDSTCMVKIATRII
                     EFFHHESCGKCTPCREGLNWTVKVLRRIEAGEGETGDLEQLEMLCKGIFGNTFCALGD
                     GAAMGLRAALKHFREEFVAHIEERRCPFH"
     misc_feature    complement(53447..54673)
                     /locus_tag="Smed_3618"
                     /note="NADH-quinone oxidoreductase, F subunit; Region:
                     nuoF_fam; TIGR01959"
                     /db_xref="CDD:131014"
     misc_feature    complement(53813..53968)
                     /locus_tag="Smed_3618"
                     /note="SLBB domain; Region: SLBB; pfam10531"
                     /db_xref="CDD:220798"
     misc_feature    complement(53570..53707)
                     /locus_tag="Smed_3618"
                     /note="NADH-ubiquinone oxidoreductase-F iron-sulfur
                     binding region; Region: NADH_4Fe-4S; smart00928"
                     /db_xref="CDD:197996"
     gene            complement(54689..55198)
                     /locus_tag="Smed_3619"
                     /db_xref="GeneID:5318150"
     CDS             complement(54689..55198)
                     /locus_tag="Smed_3619"
                     /note="TIGRFAM: NADH-quinone oxidoreductase, E subunit;
                     PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit;
                     KEGG: sme:SMa1526 NADH dehydrogenase I chain E"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit E"
                     /protein_id="YP_001312366.1"
                     /db_xref="GI:150375770"
                     /db_xref="InterPro:IPR002023"
                     /db_xref="GeneID:5318150"
                     /translation="MTMREEIEAAAARYPDRRSAIMPALMIAQKEHGHLPGPVLEDVA
                     EILGVERVWVYELVTFYTLFHTEPIGRFHLQLCDNVSCMLCGSEALLKHLETTLRIKK
                     GETTADGVFTLSTVECLGACEMAPVMQVGDDYHGNLDNARLEAMLESFRAAERVASVE
                     RAHPPSPGE"
     misc_feature    complement(54749..55183)
                     /locus_tag="Smed_3619"
                     /note="NADH-quinone oxidoreductase, E subunit; Region:
                     nuoE_fam; TIGR01958"
                     /db_xref="CDD:131013"
     misc_feature    complement(54749..54988)
                     /locus_tag="Smed_3619"
                     /note="TRX-like [2Fe-2S] Ferredoxin (Fd) family,
                     NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily;
                     Nuo, also called respiratory chain Complex 1, is the entry
                     point for electrons into the respiratory chains of
                     bacteria and the mitochondria of eukaryotes; Region:
                     TRX_Fd_NuoE; cd03064"
                     /db_xref="CDD:239362"
     misc_feature    complement(order(54848..54856,54974..54976,54980..54982))
                     /locus_tag="Smed_3619"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239362"
     misc_feature    complement(order(54833..54835,54845..54847,54953..54955,
                     54968..54970))
                     /locus_tag="Smed_3619"
                     /note="[2Fe-2S] cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239362"
     gene            complement(55217..56431)
                     /locus_tag="Smed_3620"
                     /db_xref="GeneID:5318151"
     CDS             complement(55217..56431)
                     /locus_tag="Smed_3620"
                     /EC_number="1.6.99.5"
                     /note="TIGRFAM: NADH dehydrogenase I, D subunit;
                     PFAM: NADH-ubiquinone oxidoreductase chain 49kDa;
                     KEGG: sme:SMa1529 NADH dehydrogenase I chain D"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase I subunit D"
                     /protein_id="YP_001312367.1"
                     /db_xref="GI:150375771"
                     /db_xref="InterPro:IPR001135"
                     /db_xref="InterPro:IPR010219"
                     /db_xref="GeneID:5318151"
                     /translation="MTEVTELMRPEGEALNTKEVLLNLGPQHPSTHGVLRLVLQLDGE
                     YVERIDPHIGYLHRGTEKLAESFTYTQIFPLTDRLDYLCPPSNNLAFALAVEKLLGIE
                     APIRAQYIRVMMAELARISGHLLITGALPMDLGAMTALLYAMREREMIMDLLEMITGA
                     RMHTSYCRVGGVREDLPDGFLPKIREFCEIFPNRIRDYERLIENNRVFLSRTQGIGVI
                     SAADAVDLGLSGPNLRASGVDWDIRRDEPYEIYDRLDFDVITREEGDCYARWLCRVDE
                     MRESIRLIEQCMEQMPEGPFQVDIPTIAFPVDKERVHCSMEALIQHFDLSAYGFDVPA
                     GEVYSVIEAPKGELGFYIISDGSPKPFRMKVRAPSFVNLQALFGVTNARYLADMIAVL
                     GSLDPVMAEVDK"
     misc_feature    complement(55220..56380)
                     /locus_tag="Smed_3620"
                     /note="NADH dehydrogenase I, D subunit; Region: NuoD;
                     TIGR01962"
                     /db_xref="CDD:233658"
     misc_feature    complement(55223..56380)
                     /locus_tag="Smed_3620"
                     /note="NADH dehydrogenase subunit D; Validated; Region:
                     PRK06075"
                     /db_xref="CDD:180385"
     gene            complement(56449..56997)
                     /locus_tag="Smed_3621"
                     /db_xref="GeneID:5318152"
     CDS             complement(56449..56997)
                     /locus_tag="Smed_3621"
                     /EC_number="1.6.99.5"
                     /note="TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C;
                     PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit;
                     KEGG: sme:SMa1531 NADH dehydrogenase I chain C"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH (or F420H2) dehydrogenase subunit C"
                     /protein_id="YP_001312368.1"
                     /db_xref="GI:150375772"
                     /db_xref="InterPro:IPR001268"
                     /db_xref="InterPro:IPR010218"
                     /db_xref="GeneID:5318152"
                     /translation="MTGERPVDLLSIIGSFVGAVEGLGAAHGIHAFAVPPEQIVEFCR
                     FLKEHPALQFSFLSDICGVDHYPDLPRFETVYHLYSLNNKWRVRIKCRLGDPPHVPSV
                     TGVWRTANWHEREAWDMYGIRFEGHPDLRRIYMWEGFEGFPQRKDFPLRGYKDKLNPF
                     GAEGPPPTQPDLATRDIPQGGH"
     misc_feature    complement(56485..56967)
                     /locus_tag="Smed_3621"
                     /note="NADH:ubiquinone oxidoreductase 27 kD subunit
                     [Energy production and conversion]; Region: NuoC; COG0852"
                     /db_xref="CDD:223921"
     misc_feature    complement(56542..56907)
                     /locus_tag="Smed_3621"
                     /note="NADH (or F420H2) dehydrogenase, subunit C; Region:
                     NuoC_fam; TIGR01961"
                     /db_xref="CDD:233657"
     gene            complement(56994..57497)
                     /locus_tag="Smed_3622"
                     /db_xref="GeneID:5318153"
     CDS             complement(56994..57497)
                     /locus_tag="Smed_3622"
                     /EC_number="1.6.99.5"
                     /note="The point of entry for the majority of electrons
                     that traverse the respiratory chain eventually resulting
                     in the reduction of oxygen"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase subunit B"
                     /protein_id="YP_001312369.1"
                     /db_xref="GI:150375773"
                     /db_xref="InterPro:IPR006137"
                     /db_xref="InterPro:IPR006138"
                     /db_xref="GeneID:5318153"
                     /translation="MAGVNDAIRDSVLFTTAESIISWSRRSALWPETFGIACCAIEMI
                     SAGCARYDLDRFGVVFRPSPRQSDVMIIAGTVTRKFAPVVRRLYDQMPEPRWVIAMGT
                     CAISGGVYNTYAVVQGSETFVPVDVHVPGCPPRPEALMHGFLLLQEKIKTSRALTGTP
                     LGRVVAS"
     misc_feature    complement(57033..57497)
                     /locus_tag="Smed_3622"
                     /note="NADH dehydrogenase subunit B; Validated; Region:
                     PRK06411"
                     /db_xref="CDD:235797"
     gene            complement(57485..57850)
                     /locus_tag="Smed_3623"
                     /db_xref="GeneID:5318154"
     CDS             complement(57485..57850)
                     /locus_tag="Smed_3623"
                     /note="PFAM: NADH-ubiquinone/plastoquinone oxidoreductase
                     chain 3;
                     KEGG: sme:SMa1533 NADH dehydrogenase I chain A"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-ubiquinone/plastoquinone oxidoreductase
                     chain 3"
                     /protein_id="YP_001312370.1"
                     /db_xref="GI:150375774"
                     /db_xref="InterPro:IPR000440"
                     /db_xref="GeneID:5318154"
                     /translation="MTAMEFLPVLFMVAGIVLVAAATLFVSSLLRPSNPYPEKNAPYE
                     CGMEAAGEAAGGRFRVPFFILAILLVIFDVEAMFLFPWAVVLKEIGIVGYIEMFVFML
                     LLLVGFAYAWLKGALEWQE"
     misc_feature    complement(57491..57850)
                     /locus_tag="Smed_3623"
                     /note="NADH:ubiquinone oxidoreductase subunit 3 (chain A)
                     [Energy production and conversion]; Region: NuoA; COG0838"
                     /db_xref="CDD:223908"
     sig_peptide     complement(57785..57850)
                     /locus_tag="Smed_3623"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.884) with cleavage site probability 0.591 at
                     residue 22"
     gene            complement(58063..59502)
                     /locus_tag="Smed_3624"
                     /db_xref="GeneID:5318155"
     CDS             complement(58063..59502)
                     /locus_tag="Smed_3624"
                     /EC_number="1.6.99.5"
                     /note="TIGRFAM: proton-translocating NADH-quinone
                     oxidoreductase, chain N;
                     PFAM: NADH/Ubiquinone/plastoquinone (complex I);
                     KEGG: sme:SMa1535 NADH dehydrogenase I chain N"
                     /codon_start=1
                     /transl_table=11
                     /product="proton-translocating NADH-quinone oxidoreductase
                     subunit N"
                     /protein_id="YP_001312371.1"
                     /db_xref="GI:150375775"
                     /db_xref="InterPro:IPR001750"
                     /db_xref="InterPro:IPR010096"
                     /db_xref="GeneID:5318155"
                     /translation="MTAVALLQWVLASVPEIIVVTGACILLIVGELVRKGRDELLLWA
                     AVAIVLLAAVATLMLAGEIRPAYAGMFISDSFAVFFKLVFYLATVLTFFLSRKYAEIE
                     GIGRSEYYVLLLFALLGMMIMASAIDLLSIYVGLELMVLCTYVLTGFLRKERRSNEAA
                     LKYVILGAVSTAIFLYGVSLIYGLTGTTQLDRMAEAVSGGPFDPALLLAVVFIVAGLV
                     FKIGAVPFHMWVPDVYEGAPTTITAFMSVAPKAAGFAVILRVFLNPLVEASNAWIIVA
                     AIAVATMALGSFVALVQDNFKRLLAYSSIAHAGFAIFGVVAGGQDGIASVMLYLLIYA
                     FMNLGIFGAVIMMRNGDFSGEVIDDYAGFAKFHPGLALLMLLYLFSLAGIPPTAGFFA
                     KFYVLVALVERGFVALAVIAALLSVIAAYFYIRIVMVIYMREPERTFDPALTPLVRAT
                     LAFTAVGTIGIGLFPAWFLRLAQQAAFGG"
     misc_feature    complement(58096..59472)
                     /locus_tag="Smed_3624"
                     /note="proton-translocating NADH-quinone oxidoreductase,
                     chain N; Region: NDH_I_N; TIGR01770"
                     /db_xref="CDD:233565"
     misc_feature    complement(58303..59121)
                     /locus_tag="Smed_3624"
                     /note="NADH-Ubiquinone/plastoquinone (complex I), various
                     chains; Region: Oxidored_q1; pfam00361"
                     /db_xref="CDD:201180"
     gene            complement(59499..60974)
                     /locus_tag="Smed_3625"
                     /db_xref="GeneID:5318156"
     CDS             complement(59499..60974)
                     /locus_tag="Smed_3625"
                     /EC_number="1.6.99.5"
                     /note="TIGRFAM: proton-translocating NADH-quinone
                     oxidoreductase, chain M;
                     PFAM: NADH/Ubiquinone/plastoquinone (complex I);
                     KEGG: sme:SMa1536 NuoM2 NADH-Ubiquinone/plastoquinone
                     (complex I) oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="proton-translocating NADH-quinone oxidoreductase
                     subunit M"
                     /protein_id="YP_001312372.1"
                     /db_xref="GI:150375776"
                     /db_xref="InterPro:IPR001750"
                     /db_xref="InterPro:IPR003918"
                     /db_xref="InterPro:IPR010227"
                     /db_xref="GeneID:5318156"
                     /translation="MSIPLLSLIVFVPVAGAAVLVFMRSDDAVRWTALGFGIVDLALC
                     IVMLAGFDTTTHEMQFVESRPWVAALGIAYALGVDGISALFLFLTALLGLISVLASWV
                     AIDRKVKEFMVSLLVMQALMLGVFCALDLFLFYVFWEAMLIPMYLIIGVWGGEGRVYA
                     AFKFFLYTLAGSILFLIGVIVLYFQGGETFDILALTAQDLPFGVQSWLFFAFLVAFAV
                     KVPMVPVHTWLPDAHVQAPTAGSIILAGVLLKMGAYGFLRFSLPMLPEASLYYSTLML
                     LLSALAIVYGGLLALAQDDLKKLVAYSSISHMGFVTLGIFALNLRGLEGSILQMFNHG
                     ITTGALFLFVGLIYERTHTRSIANYGGLMKAAPIYTAFLALFTLSSMALPGTNAFVGE
                     LLVLSGGFAANLAAGTAAVVGALLSAAYLLGMYGKVALGPPSVSAKYKIHDVNGREMA
                     AILPLAIFVLWVGLYPRPFLGIIDASVRNLLVQVHGEGIGQ"
     sig_peptide     complement(60921..60974)
                     /locus_tag="Smed_3625"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.919) with cleavage site probability 0.855 at
                     residue 18"
     misc_feature    complement(59523..60959)
                     /locus_tag="Smed_3625"
                     /note="proton-translocating NADH-quinone oxidoreductase,
                     chain M; Region: NDH_I_M; TIGR01972"
                     /db_xref="CDD:200147"
     misc_feature    complement(59784..60593)
                     /locus_tag="Smed_3625"
                     /note="NADH-Ubiquinone/plastoquinone (complex I), various
                     chains; Region: Oxidored_q1; pfam00361"
                     /db_xref="CDD:201180"
     gene            complement(60982..62742)
                     /locus_tag="Smed_3626"
                     /db_xref="GeneID:5318312"
     CDS             complement(60982..62742)
                     /locus_tag="Smed_3626"
                     /EC_number="1.6.5.3"
                     /note="subunit D of antiporter complex involved in
                     resistance to high concentrations of Na+, K+, Li+ and/or
                     alkali; contains an oxidoreductase domain; catalyzes the
                     transfer of electrons from NADH to ubiquinone; in S.
                     meliloti it is known to be involved specifically with K+
                     transport"
                     /codon_start=1
                     /transl_table=11
                     /product="putative monovalent cation/H+ antiporter subunit
                     D"
                     /protein_id="YP_001312373.1"
                     /db_xref="GI:150375777"
                     /db_xref="InterPro:IPR001750"
                     /db_xref="InterPro:IPR003916"
                     /db_xref="InterPro:IPR003918"
                     /db_xref="GeneID:5318312"
                     /translation="MTDFVHPALIFILGALPIPFFTGLVRKSYLVLIPVLAIVAVMAI
                     EPGSYGETQFLGQEILIAKVDKLSIVFATVFTIMALIGTVYALHLSGAGEHVAAFVYV
                     GSALGVVFAGDYLTLYLFWEGMAFASAYLVFAQGAGQAIRAAFRYLMVHVTGGVVLLG
                     GILLHGAAAGSLLFGPVEGALDAGAYLILAGFLLNAAVPPLNAWLTDAYPEATVTGAV
                     FMSAFTTKTAVYVLARAFPGIELLVWLGTVMALYGVIYAVLENDCRRLLAYHIVSQVG
                     YMVAGIGIGTELAVNGATSHAFAHILYKGLLFMGAGAVIYVTGRRKLSELGGLYKAMP
                     LTVAFYMAGALAISAFPFFSGFVSKSMVIAAAAQDHRALVMLALTMASSGTFLHTGLK
                     LPYYMFLGTDRGLQAREPPGNMLVAMGVAAALCIAIGIFPGPLYALLPYPVDFEPYTG
                     VHVSESLGILMFTALGFVIFLRALDPESTISLDTDWFYRKGARAFMWFAERPLARYEK
                     AVSDVSETAVLPFLHGSARTGMRLDLNGVDGVVNGVARSILDGGGVLRRLQTGVVTHY
                     VLAMIAGLIAAILVFAVVWR"
     misc_feature    complement(61060..62742)
                     /locus_tag="Smed_3626"
                     /note="putative monovalent cation/H+ antiporter subunit D;
                     Reviewed; Region: PRK12668"
                     /db_xref="CDD:237168"
     misc_feature    complement(61645..62412)
                     /locus_tag="Smed_3626"
                     /note="NADH-Ubiquinone/plastoquinone (complex I), various
                     chains; Region: Oxidored_q1; pfam00361"
                     /db_xref="CDD:201180"
     gene            complement(62735..62989)
                     /locus_tag="Smed_3627"
                     /db_xref="GeneID:5318313"
     CDS             complement(62735..62989)
                     /locus_tag="Smed_3627"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312374.1"
                     /db_xref="GI:150375778"
                     /db_xref="GeneID:5318313"
                     /translation="MIKPVVGFFGDEQYARPRRRLFYLVLFLIIVADFLVSRDHAEYL
                     WERLPGWSAAYGFGSCVLLIFVSKFLGHRAGLMRREDYYD"
     gene            complement(62986..64449)
                     /locus_tag="Smed_3628"
                     /db_xref="GeneID:5318314"
     CDS             complement(62986..64449)
                     /locus_tag="Smed_3628"
                     /EC_number="1.6.99.5"
                     /note="subunit D of antiporter complex involved in
                     resistance to high concentrations of Na+, K+, Li+ and/or
                     alkali; contains an oxidoreductase domain; catalyzes the
                     transfer of electrons from NADH to ubiquinone"
                     /codon_start=1
                     /transl_table=11
                     /product="putative monovalent cation/H+ antiporter subunit
                     D"
                     /protein_id="YP_001312375.1"
                     /db_xref="GI:150375779"
                     /db_xref="InterPro:IPR001750"
                     /db_xref="InterPro:IPR003916"
                     /db_xref="InterPro:IPR003918"
                     /db_xref="GeneID:5318314"
                     /translation="MDPVISTRPLLAVAVAGLAALAILFLNKREKLRDAVSPIAAVAM
                     FAIVVSMAPTVLAGGTVELRLFEVLPGIDFGFRADALGMVFATVSSLLWIVAAVYSIG
                     YMRHLHEHAQTRFFACFATSLAAAVGGAFAANLFTLVIFYEVLSLVTYPLVYHHEDEE
                     GWRGSRKYLVYLMGASKSVLLAALALTYHIAGSLDFVTGGLLAGANASATLLAVVYFC
                     YLFGFAKAAVMPMHAWLPAAMVAPTPVSALLHAVAVVKMGVFCVLRVIFHVFGVSMVG
                     ELGLGVATAYLVSFTILMASIYALTRDDLKARLAYSTVSQLSYIVLGAVLLSPLAMVG
                     GIIHIAAHAFSKITLFFCAGSIYCASGKRNISDMAGIGRRLPWTMGAFFVASLSMIGI
                     PPTAGFVSKWYLAEGSVEAGQMAFLAVLLASSVLNAAYFLPVSYTAFFEAETKESQAP
                     VREIPLVAIPLVATAILSVLMGIFPYYFLTLADGVIQ"
     misc_feature    complement(62989..64371)
                     /locus_tag="Smed_3628"
                     /note="putative monovalent cation/H+ antiporter subunit D;
                     Reviewed; Region: PRK08375"
                     /db_xref="CDD:236251"
     misc_feature    complement(63226..64050)
                     /locus_tag="Smed_3628"
                     /note="NADH-Ubiquinone/plastoquinone (complex I), various
                     chains; Region: Oxidored_q1; pfam00361"
                     /db_xref="CDD:201180"
     gene            complement(64454..64756)
                     /locus_tag="Smed_3629"
                     /db_xref="GeneID:5318315"
     CDS             complement(64454..64756)
                     /locus_tag="Smed_3629"
                     /note="PFAM: NADH-ubiquinone oxidoreductase chain 4L;
                     KEGG: sme:SMa1544 NADH dehydrogenase I chain K"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-ubiquinone oxidoreductase chain 4L"
                     /protein_id="YP_001312376.1"
                     /db_xref="GI:150375780"
                     /db_xref="InterPro:IPR001133"
                     /db_xref="InterPro:IPR003214"
                     /db_xref="GeneID:5318315"
                     /translation="MVPLSWSILLGVALFVIGAGGVLLRRNILIVLMSLELLLNSVNI
                     NFIAFGQYYDDFRGQIFAIFVIAITAAEVAVALGILVALVRNKSTLKVDDVTIMKG"
     misc_feature    complement(64457..64756)
                     /locus_tag="Smed_3629"
                     /note="NADH-ubiquinone/plastoquinone oxidoreductase chain
                     4L; Region: Oxidored_q2; cl00492"
                     /db_xref="CDD:241901"
     gene            complement(64756..65256)
                     /locus_tag="Smed_3630"
                     /db_xref="GeneID:5318316"
     CDS             complement(64756..65256)
                     /locus_tag="Smed_3630"
                     /note="PFAM: NADH-ubiquinone/plastoquinone oxidoreductase
                     chain 6;
                     KEGG: sme:SMa1545 putative oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-ubiquinone/plastoquinone oxidoreductase
                     chain 6"
                     /protein_id="YP_001312377.1"
                     /db_xref="GI:150375781"
                     /db_xref="InterPro:IPR001457"
                     /db_xref="GeneID:5318316"
                     /translation="MHQGFFLLFATVSVVTALTLVLARNPVHSALALMACFLQISAIF
                     VMLGAPLLAVIQIFVYVGAIMVLFLFVIMMVDVREAVLQRFMPGGNLPALALLLLLGT
                     EMVVLVLWSDRFIESPPVAERGGDAIRDLSKTLFSDYLLPFEIASVILLAALVGAIVL
                     ARKEPG"
     sig_peptide     complement(65167..65256)
                     /locus_tag="Smed_3630"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.966) with cleavage site probability 0.607 at
                     residue 30"
     misc_feature    complement(<64825..65187)
                     /locus_tag="Smed_3630"
                     /note="NADH:ubiquinone oxidoreductase subunit J;
                     Provisional; Region: PRK06638"
                     /db_xref="CDD:235844"
     misc_feature    complement(65035..>65187)
                     /locus_tag="Smed_3630"
                     /note="NADH dehydrogenase subunit J; Provisional; Region:
                     PRK06433"
                     /db_xref="CDD:180562"
     gene            complement(65645..65833)
                     /locus_tag="Smed_3631"
                     /db_xref="GeneID:5318317"
     CDS             complement(65645..65833)
                     /locus_tag="Smed_3631"
                     /note="KEGG: rle:pRL100452 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312378.1"
                     /db_xref="GI:150375782"
                     /db_xref="GeneID:5318317"
                     /translation="MEHVEAEKLSKHTVTKIWNVREFCQLHQLGDKEEIRLRRLFGRF
                     ATASELQHNAKRTPKWRY"
     gene            66248..66730
                     /locus_tag="Smed_3632"
                     /pseudo
                     /db_xref="GeneID:5318318"
     gene            complement(67110..67826)
                     /locus_tag="Smed_3633"
                     /db_xref="GeneID:5318319"
     CDS             complement(67110..67826)
                     /locus_tag="Smed_3633"
                     /EC_number="4.1.2.17"
                     /note="PFAM: class II aldolase/adducin family protein;
                     KEGG: sme:SMb20490 putative L-fuculose phosphate aldolase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose phosphate aldolase"
                     /protein_id="YP_001312379.1"
                     /db_xref="GI:150375783"
                     /db_xref="InterPro:IPR001303"
                     /db_xref="GeneID:5318319"
                     /translation="MAETDKLALRREMVDICRRMNSSGINQGTAGNLSLRTDDGFLIT
                     PSSMPYETMQPEDLVEMAFDGTYVGHRPSSEWRFHRDILRARTDIDVVLHCHSIYATT
                     LACHHKTIPSFHYMTGIAGGTTIRCAEYATFGTQALSDNALVALKGRLACLLGQHGQI
                     SLGKTLEQALWLAIEVETLSRIYVQALTLGEPPVLPDDEMERVIAQMRRMSYGQAPDA
                     EGVNDVARPRDALGNSGKSV"
     misc_feature    complement(67188..67814)
                     /locus_tag="Smed_3633"
                     /note="Class II Aldolase and Adducin head (N-terminal)
                     domain. Aldolases are ubiquitous enzymes catalyzing
                     central steps of carbohydrate metabolism. Based on
                     enzymatic mechanisms, this superfamily has been divided
                     into two distinct classes (Class I and II); Region:
                     Aldolase_II; cl00214"
                     /db_xref="CDD:241692"
     misc_feature    complement(order(67272..67274,67293..67295,67305..67307,
                     67326..67328,67359..67361,67437..67439,67479..67484,
                     67488..67490,67512..67514,67515..67517,67530..67535,
                     67539..67541,67671..67676,67680..67682,67746..67748,
                     67770..67772,67782..67784))
                     /locus_tag="Smed_3633"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238232"
     misc_feature    complement(order(67356..67358,67539..67541,67545..67547,
                     67602..67610,67686..67691,67731..67733))
                     /locus_tag="Smed_3633"
                     /note="active site"
                     /db_xref="CDD:238232"
     misc_feature    complement(order(67356..67358,67539..67541,67545..67547))
                     /locus_tag="Smed_3633"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238232"
     gene            complement(67839..69287)
                     /locus_tag="Smed_3634"
                     /db_xref="GeneID:5318320"
     CDS             complement(67839..69287)
                     /locus_tag="Smed_3634"
                     /note="PFAM: carbohydrate kinase FGGY;
                     KEGG: sme:SMb20489 putative carbohydrate kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase FGGY"
                     /protein_id="YP_001312380.1"
                     /db_xref="GI:150375784"
                     /db_xref="InterPro:IPR000577"
                     /db_xref="GeneID:5318320"
                     /translation="MNDSGSGAAAVAVLDVGKTNVKLSAFTADGAAVETLSVPNPVLP
                     GPPWRHHDVTALSQWVFETLAALSRRHDLSAIVTAGHGSGGVLTGTDPDAGDGATLPM
                     IDYEQSLPPDILDGYTPLAGSFLDRGSATMHGATHQARQLYWMEARQPDAFGKARWFL
                     GLPQYWAWRLSGIAASEASFLGAQSHLWNVAERRWAPIVGARGWERLMPPFAKAWQTL
                     GPIRPELVKRYGLPAEMRVLAGGHDSSLNHYRYHAAGLQDFTVISTGTWIVGFSRSTP
                     IDRLDEHRGMTLNSDLFGNRLGGILTMGGREFSHIAGVDPPTDNAPPEVLVRLLAQRT
                     IAAPSFGDDDGLFPGSAGSGRILGPEPKSAMERKTLALLYCALLTVECIETLSADRLV
                     VLDGSFLRDPLYADVVAALLPDRKVCFNLDAYGVAAGAALLAGHETRKGPAPLTLSEP
                     TRFGRLEPELLRYAADWRAVARTTATETNSGT"
     misc_feature    complement(68052..69272)
                     /locus_tag="Smed_3634"
                     /note="Sugar (pentulose and hexulose) kinases
                     [Carbohydrate transport and metabolism]; Region: XylB;
                     COG1070"
                     /db_xref="CDD:223996"
     misc_feature    complement(68028..69260)
                     /locus_tag="Smed_3634"
                     /note="Novosphingobium aromaticivorans carbohydrate
                     kinase-like proteins; belongs to the FGGY family of
                     carbohydrate kinases; Region: FGGY_NaCK_like; cd07772"
                     /db_xref="CDD:198350"
     misc_feature    complement(order(68400..68402,68406..68432,68448..68450,
                     68454..68456,68475..68477,68505..68507,68538..68546,
                     68550..68555,68565..68567,68574..68576,68646..68651,
                     68718..68720,68724..68726,68736..68744,68751..68759,
                     68895..68900,68904..68906,68913..68918,69057..69059,
                     69063..69065,69183..69185,69192..69200,69210..69212,
                     69216..69218,69222..69224,69243..69245,69249..69251,
                     69255..69257))
                     /locus_tag="Smed_3634"
                     /note="N- and C-terminal domain interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:198350"
     misc_feature    complement(order(68085..68087,68094..68102,68322..68324,
                     68361..68363,68373..68375,68481..68483,68490..68498,
                     68556..68561,68973..68975,69039..69041,69045..69047,
                     69222..69224,69228..69239,69243..69245))
                     /locus_tag="Smed_3634"
                     /note="putative active site [active]"
                     /db_xref="CDD:198350"
     misc_feature    complement(order(68085..68087,68094..68102,68313..68315,
                     68319..68324,68361..68366,68370..68375,68490..68498,
                     68559..68561,69222..69224,69228..69239,69243..69245))
                     /locus_tag="Smed_3634"
                     /note="putative MgATP binding site [chemical binding];
                     other site"
                     /db_xref="CDD:198350"
     misc_feature    complement(order(68559..68561,69234..69236,69243..69245))
                     /locus_tag="Smed_3634"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:198350"
     misc_feature    complement(order(68559..68561,69243..69245))
                     /locus_tag="Smed_3634"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:198350"
     misc_feature    complement(order(68481..68483,68490..68492,68556..68561,
                     68880..68882,68973..68975,69039..69041,69045..69047,
                     69234..69239))
                     /locus_tag="Smed_3634"
                     /note="putative carbohydrate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:198350"
     gene            complement(69334..70182)
                     /locus_tag="Smed_3635"
                     /db_xref="GeneID:5318321"
     CDS             complement(69334..70182)
                     /locus_tag="Smed_3635"
                     /note="PFAM: Xylose isomerase domain protein TIM barrel;
                     KEGG: sme:SMb20488 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase domain-containing protein"
                     /protein_id="YP_001312381.1"
                     /db_xref="GI:150375785"
                     /db_xref="InterPro:IPR012307"
                     /db_xref="GeneID:5318321"
                     /translation="MQGFGVHTSMWTMNWDRPGAERAVVAAVKYKVDFIEIPMLNPPA
                     VDTEHTRALLEKHRLRAVCSLGLPEPAWASVRPDAAIDHLKIAIDKTADLGGEALSGV
                     IYGGIGERTGVPPTVEEYDNIARVLQAAAKHAKSRGIELGVEAVNRYENHLINTGWQA
                     VKMIERVGADNVFVHLDTYHMNIEEKGIGKGILDAREHLKYIHLSESDRGTPGYGTCG
                     WDEIFSTLAAIGFKGGLAMESFINMPPEVAYGLAVWRPVAKDEEEVMGNGLPFLRNKA
                     TQYGLI"
     misc_feature    complement(69445..70173)
                     /locus_tag="Smed_3635"
                     /note="Sugar phosphate isomerases/epimerases [Carbohydrate
                     transport and metabolism]; Region: IolE; COG1082"
                     /db_xref="CDD:224007"
     misc_feature    complement(69481..>69951)
                     /locus_tag="Smed_3635"
                     /note="AP endonuclease family 2; These endonucleases play
                     a role in DNA repair. Cleave phosphodiester bonds at
                     apurinic or apyrimidinic sites; the alignment also
                     contains hexulose-6-phosphate isomerases, enzymes that
                     catalyze the epimerization of...; Region: AP2Ec; cl12060"
                     /db_xref="CDD:245856"
     misc_feature    complement(order(69553..69555,69559..69561,69574..69576,
                     69643..69645,69652..69654,69751..69753,69871..69873))
                     /locus_tag="Smed_3635"
                     /note="Metal-binding active site; metal-binding site"
                     /db_xref="CDD:237986"
     gene            complement(70185..71183)
                     /locus_tag="Smed_3636"
                     /db_xref="GeneID:5318178"
     CDS             complement(70185..71183)
                     /locus_tag="Smed_3636"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20487 putative sugar ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="YP_001312382.1"
                     /db_xref="GI:150375786"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318178"
                     /translation="MTAVFERIKATLGPEMAGPGLAFVAVFVVFGFASPQFLSSATFG
                     SVAFQLPELGLLTLAMLLPILTGGLNLAITFTANLAGLTLAWVLKANGGVDAGFGIFL
                     VGSLLAVMVGAASGVVMGLVIAFTRAHPILVSLSMMIFLRGLGEFLTRGGDISGFPSF
                     VGVIGHGSVAGIPVPLIVFIVCVLAWHLLLGRTKLGFNTYMIGSNLEATRYSGINTRK
                     AIVLVYTLSGIMCAIAGIIMLARFNSVRVGHGESYLLITVLACFLGGVNPFGGFGRVI
                     PVFVALVVLQLLSSGLNLIGANQHLATAVWGILLVGVMILRWVASKIKFSIVRRGS"
     misc_feature    complement(70236..70982)
                     /locus_tag="Smed_3636"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(70242..>70817)
                     /locus_tag="Smed_3636"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(70509..70565)
                     /locus_tag="Smed_3636"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(71180..72181)
                     /locus_tag="Smed_3637"
                     /db_xref="GeneID:5318179"
     CDS             complement(71180..72181)
                     /locus_tag="Smed_3637"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20486 putative sugar ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001312383.1"
                     /db_xref="GI:150375787"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318179"
                     /translation="MHSLIRTHATEFSLLGVIVVISAVLSFATANFLSLGNAFDLLNI
                     SSVNIIFAVGLLVVLIAGGIDISFAVAASVVQYGTAIALGWIGGGGWLSGFVIAASLG
                     VLLGCVNALLIHRFRIISIVATIATFNIYFGLLMFFTRGVSIYDLPDWLTDRVILFER
                     EMPDGTWIEITLPVLVMIICVVATWTLITRTTIGRQLFAFGDNPEGARRFGINIGAMQ
                     FIAFGWLGLMAGIGGLVQAHYAQEVVPNALYGRELDVLAAVVLGGARLGGGKGTVLGC
                     VLGVLLISITQNGLNLMGVSPFAFKMIIGAIILIAITLSNTRLERLLPFAGWKGTRR"
     sig_peptide     complement(72095..72181)
                     /locus_tag="Smed_3637"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.894) with cleavage site probability 0.536 at
                     residue 29"
     misc_feature    complement(<71432..72073)
                     /locus_tag="Smed_3637"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(71276..72049)
                     /locus_tag="Smed_3637"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(71513..71569)
                     /locus_tag="Smed_3637"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(72174..73700)
                     /locus_tag="Smed_3638"
                     /db_xref="GeneID:5318180"
     CDS             complement(72174..73700)
                     /locus_tag="Smed_3638"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20485 putative sugar ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312384.1"
                     /db_xref="GI:150375788"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318180"
                     /translation="MGHGSMHQSASAARTDQPLLSLRNINMTFGGVKALKNVTFEVRP
                     GEVHCLAGENGSGKSTLIKVITGVYRPAEGAIIEYDGDVYPHMSPVTAQERGIQVIWQ
                     DLALFPEMSVAENIAFHEVLGRPRLVDYSRMRQIAIEALSRLGITLDVDLPLKEYAIA
                     QRQIVAIARALVGEAKVVFMDEPTASLTQSETDYLLEIVRGLSASGVAVVFVSHRLAE
                     VLEISSRITVLRDGALVGVYPADGMTQSKITELMTGKTFDQHVRARAKDDQPVVLDVR
                     GLGSPGQFEDVSLTVRRGETVGITGLLGAGRTELALALFGMLKPTSGTFSIDGREARF
                     ASNRDAIKAGVAYLSEDRLSLGLIQPQSIADNLVIASLHKILSGGLLADDRKRSLVAR
                     WIADLGVKIGHQADAISTLSGGNQQRVAIAKWLATDPKLLILDSPTVGVDVGARAGIF
                     DIVAKLAESGLAIILISDEVPEVYFNADRVLHMAQGRIVGIYDPHQTRLEEIEAAVYA
                     "
     misc_feature    complement(72177..73667)
                     /locus_tag="Smed_3638"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    complement(72990..73643)
                     /locus_tag="Smed_3638"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    complement(73524..73547)
                     /locus_tag="Smed_3638"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(73059..73061,73155..73160,73395..73397,
                     73521..73529,73533..73538))
                     /locus_tag="Smed_3638"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(73395..73406)
                     /locus_tag="Smed_3638"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(73290..73295,73296..73301,73359..73373))
                     /locus_tag="Smed_3638"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(73155..73172)
                     /locus_tag="Smed_3638"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(73137..73148)
                     /locus_tag="Smed_3638"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(73053..73073)
                     /locus_tag="Smed_3638"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(72237..72893)
                     /locus_tag="Smed_3638"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            complement(73809..74801)
                     /locus_tag="Smed_3639"
                     /db_xref="GeneID:5318181"
     CDS             complement(73809..74801)
                     /locus_tag="Smed_3639"
                     /note="KEGG: sme:SMb20484 putative ABC transporter
                     periplasmic sugar-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter periplasmic
                     sugar-binding protein"
                     /protein_id="YP_001312385.1"
                     /db_xref="GI:150375789"
                     /db_xref="InterPro:IPR000719"
                     /db_xref="GeneID:5318181"
                     /translation="MIRKILAAALAASLSLAGAYTAAAQDSGKVGIVVKIGGIPWFNA
                     MEAGIKERGEKLGVDAFMVGPTSADPALQVRAIEDLIAQNVKVIGVVPNDAKVLEPVL
                     TKAKEKGIIVITHESPSQKGADWDFELASATGFGEAHAKLLAEKMGGKGEYAVFVGSL
                     TVPLHNAWADAAIEYIKKNHSEMTLVGDRYGVAEDADKSRSTALDLISAHPNLKGFLA
                     FGSQGPIGAGRAIEERRKTGEIFVLGPFSPGQGQKLIKADAISGGFMWNPKQAGEVFV
                     TLADKLMKGEEIKDGDEIEGLGVIHPDFENRNIIVDQLVPINKETVADLAAMGL"
     sig_peptide     complement(74727..74801)
                     /locus_tag="Smed_3639"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.406 at
                     residue 25"
     misc_feature    complement(73836..74684)
                     /locus_tag="Smed_3639"
                     /note="Periplasmic binding domain of autoinducer-2 (AI-2)
                     receptor LsrB from Salmonella typhimurium and its close
                     homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302"
                     /db_xref="CDD:107297"
     misc_feature    complement(73956..74684)
                     /locus_tag="Smed_3639"
                     /note="Periplasmic binding protein domain; Region:
                     Peripla_BP_4; pfam13407"
                     /db_xref="CDD:222108"
     misc_feature    complement(order(74004..74006,74139..74147,74298..74300,
                     74307..74312,74415..74417,74454..74456))
                     /locus_tag="Smed_3639"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107297"
     gene            75040..76107
                     /locus_tag="Smed_3640"
                     /db_xref="GeneID:5318182"
     CDS             75040..76107
                     /locus_tag="Smed_3640"
                     /note="PFAM: regulatory protein LacI;
                     KEGG: sme:SMb20483 putative catabolite repressor protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein LacI"
                     /protein_id="YP_001312386.1"
                     /db_xref="GI:150375790"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="GeneID:5318182"
                     /translation="MTNGGRKKATIYDLSVLSGSSPSTVSAVLNGTWRKRRIRESTAE
                     LIRSLAETHQYTANRQARGLRSSRSGLVGLLLPVHDNRYFSSLAQTFEAHVRSKGQCP
                     IVVSASRDPEEERRTAETLISYSIDELFICGATDPDGVHEVCEAAGLKHINIDLPGTK
                     VPSVISDNFEGGRILTEAIIRHFPADRPLAPEDLYLFGGRDDHATRERIRGFRAAKKE
                     LLGGDPDECVWPTGYAADNARKAFDAFYEQRGKLPRGFFVNSSINLEGLLRFMAEHPL
                     ENFKDLVVGCYDYDPFASFLPFPVIMIRQDVEGMIARAFEVIEEPRASVQIHLVKPRL
                     VPPRTALTGPLDALIDSDMPR"
     misc_feature    75064..76056
                     /locus_tag="Smed_3640"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    75268..76044
                     /locus_tag="Smed_3640"
                     /note="Ligand binding domain of DNA transcription
                     repressor specific for fructose (FruR) and its close
                     homologs; Region: PBP1_FruR; cd06274"
                     /db_xref="CDD:107269"
     misc_feature    order(75274..75276,75304..75309,75313..75318,75325..75327,
                     75340..75342,75349..75351,75355..75357,75409..75411,
                     75832..75834,75922..75924,75928..75930)
                     /locus_tag="Smed_3640"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107269"
     misc_feature    order(75286..75288,75298..75300,75496..75501,75526..75537,
                     75661..75663,75817..75819,75901..75903)
                     /locus_tag="Smed_3640"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107269"
     gene            complement(76152..77939)
                     /locus_tag="Smed_3641"
                     /db_xref="GeneID:5318183"
     CDS             complement(76152..77939)
                     /locus_tag="Smed_3641"
                     /EC_number="6.3.2.3"
                     /note="PFAM: GCN5-related N-acetyltransferase;
                     KEGG: sme:SMb20482 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="YP_001312387.1"
                     /db_xref="GI:150375791"
                     /db_xref="InterPro:IPR000182"
                     /db_xref="InterPro:IPR011761"
                     /db_xref="GeneID:5318183"
                     /translation="MKKTREIASPRQRSKGTKAVTHRLNRLRKHAQPGREPDGPRASE
                     ATKQDVVLDCGWGRLLFAQTFSDDDKLLSELREEAPSSRDIAFYVRDPHVLLSRAPQE
                     IFLDPSHTYRLDLWTYRANTRRTRGITIRRLSSEADGEGINRVYAACGMVQIRSDFFS
                     SERDERSLTYFVAQDDASGEIVGTVTGIDHQRLFNDPDRGASLWCLAVHPQARQPGIG
                     EHLVRKLAEHFQARGLSYVDLSVMHDNTLAIGLYEKLNFRRMPLFAIKRKNAINEKFF
                     AMPHQSYDALNPYARLIVDEATRRGIHVDITDAEGGFFRLSHGGRSIHCRESLSELTS
                     GVAMSICDDKAITRRMVSAAGLVVPDQMEVGEDHQAIQAFLEKHGKLVIKPARGEQGR
                     GISVGITAADALEEAIASARQVCDRVLLEACFEGQDLRLVIIDYTLVAAAIRLPPRII
                     GDGRSRIASLIEKQSRRREAATGGESRIPLDAETDRCLAEQGIDLDTVLDEGIEITVR
                     KAANLHTGGSIHDVTDTVHPDLVDAACRAARAINIPVVGIDLMVRDPALADYVFIEAN
                     ERPGLANHEPQPTAASFIELLFPGSRTAV"
     misc_feature    complement(76158..77801)
                     /locus_tag="Smed_3641"
                     /note="GNAT-family acetyltransferase TIGR03103; Region:
                     trio_acet_GNAT"
                     /db_xref="CDD:132147"
     misc_feature    complement(77220..77432)
                     /locus_tag="Smed_3641"
                     /note="N-Acyltransferase superfamily: Various enzymes that
                     characteristically catalyze the transfer of an acyl group
                     to a substrate; Region: NAT_SF; cd04301"
                     /db_xref="CDD:173926"
     misc_feature    complement(order(77283..77288,77316..77324))
                     /locus_tag="Smed_3641"
                     /note="Coenzyme A binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173926"
     misc_feature    complement(76224..76922)
                     /locus_tag="Smed_3641"
                     /note="alpha-L-glutamate ligase-related protein; Region:
                     rimK_rel_E_lig; TIGR02291"
                     /db_xref="CDD:233813"
     gene            complement(77941..79716)
                     /locus_tag="Smed_3642"
                     /db_xref="GeneID:5318184"
     CDS             complement(77941..79716)
                     /locus_tag="Smed_3642"
                     /note="TIGRFAM: asparagine synthase
                     (glutamine-hydrolyzing);
                     PFAM: glutamine amidotransferase class-II; asparagine
                     synthase;
                     KEGG: sme:SMb20481 putative asparagine synthetase
                     (glutamine amidotransferase) protein"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
                     /protein_id="YP_001312388.1"
                     /db_xref="GI:150375792"
                     /db_xref="InterPro:IPR000583"
                     /db_xref="InterPro:IPR001962"
                     /db_xref="InterPro:IPR006426"
                     /db_xref="GeneID:5318184"
                     /translation="MCGICGEIRFDGGSPSVKAVSIMSDVLAPRGPDGSGVVVRGNVG
                     LGHRRLRILDLSDKSQQPMIDPELGLSLVFNGCIYNFRELRSELEEKGYKFFSSGDTE
                     VILKAWHAWGEECVSRFHGMFAFVIHERDSGRVVMARDRFGIKPLYIAEVEGALRFAS
                     SLPALVKAGGVDTSIDVAALHNYMTFHAVVPPPRTILNGVRKLPPATLRVYERGGSFK
                     DRRYWDPPYRRQAGDAAITREEWQERLLDALRIAVKRRMIADVPVGVLLSGGVDSSLI
                     VGLLAEAGQRGLMSFSVGFEEANGEKGDEFVYSDLIAEHFGTDHRKIFVPSADLMGAL
                     PGTITAMSEPMVSYDNVGFYLLSKEVSKHVKVVQSGQGADEVFGGYHWYPPLMNSNDV
                     VGDYGKAFRDRSHAVLATQLSDLWLADHDVSGALLNEHLLRDGADTPVDQALRLDSNV
                     MLVDDPVKRVDNMTMAWGLEARVPFLDHELVELAARIPPEEKLRDGGKGILKDVARKI
                     VPSEVIDRKKGYFPVPQLKYIAGPYLDLIRDTLNSQRARERGLFRDTYLDRLFEQPSD
                     HITPLRGSELWQVGLLEMWLEAQGV"
     misc_feature    complement(77950..79716)
                     /locus_tag="Smed_3642"
                     /note="asparagine synthase family amidotransferase;
                     Region: trio_amidotrans; TIGR03104"
                     /db_xref="CDD:234108"
     misc_feature    complement(79045..79713)
                     /locus_tag="Smed_3642"
                     /note="Glutamine amidotransferases class-II (GATase)
                     asparagine synthase_B type.  Asparagine synthetase B
                     catalyses the ATP-dependent conversion of aspartate to
                     asparagine. This enzyme is a homodimer, with each monomer
                     composed of a  glutaminase domain and a...; Region: AsnB;
                     cd00712"
                     /db_xref="CDD:238364"
     misc_feature    complement(order(79417..79419,79486..79494,79570..79572,
                     79711..79713))
                     /locus_tag="Smed_3642"
                     /note="active site"
                     /db_xref="CDD:238364"
     misc_feature    complement(order(79573..79575,79612..79626,79633..79635,
                     79642..79644,79666..79668))
                     /locus_tag="Smed_3642"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238364"
     misc_feature    complement(78145..78978)
                     /locus_tag="Smed_3642"
                     /note="The C-terminal domain of Asparagine Synthase B.
                     This domain is always found associated n-terminal
                     amidotransferase domain. Family members that contain this
                     domain catalyse the conversion of aspartate to asparagine.
                     Asparagine synthetase B  catalyzes the...; Region:
                     Asn_Synthase_B_C; cd01991"
                     /db_xref="CDD:238949"
     misc_feature    complement(order(78604..78612,78649..78651,78832..78840,
                     78913..78921))
                     /locus_tag="Smed_3642"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238949"
     misc_feature    complement(order(78604..78612,78649..78651,78832..78840,
                     78913..78921))
                     /locus_tag="Smed_3642"
                     /note="Molecular Tunnel; other site"
                     /db_xref="CDD:238949"
     gene            complement(79836..80618)
                     /locus_tag="Smed_3643"
                     /db_xref="GeneID:5318185"
     CDS             complement(79836..80618)
                     /locus_tag="Smed_3643"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20480 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312389.1"
                     /db_xref="GI:150375793"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318185"
                     /translation="MTVVIEMKKETGGDGQRLFVPAERTKRRPEAIADRIKDYIRSEG
                     LAPGDRLPQERDLIDTFKAAKGTVREAMKALETQGLVFTRSGPGGGAFVAQPSARHAM
                     ELLSTHFFFDQPSIRDIYAIRKVLEPEVAGLLAGRMRREELAALENTIRIYDHPPADL
                     EEQYRQRIAELDFHSMLAQLCPNPLLGFVCGLMHNLLRELPAARSIYADPTPLSREKG
                     LSFQYRLMAALQDGRSDDARAIATEHMAFAESYMLEREAATG"
     misc_feature    complement(79842..80558)
                     /locus_tag="Smed_3643"
                     /note="Transcriptional regulators [Transcription]; Region:
                     FadR; COG2186"
                     /db_xref="CDD:225097"
     misc_feature    complement(80337..80531)
                     /locus_tag="Smed_3643"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(80346..80357,80367..80372,80400..80402,
                     80409..80414,80418..80432,80454..80459,80463..80465))
                     /locus_tag="Smed_3643"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(79881..80267)
                     /locus_tag="Smed_3643"
                     /note="This entry represents the C-terminal ligand binding
                     domain of many members of the GntR family; Region: FCD;
                     smart00895"
                     /db_xref="CDD:214892"
     gene            complement(80625..81422)
                     /locus_tag="Smed_3644"
                     /db_xref="GeneID:5318186"
     CDS             complement(80625..81422)
                     /locus_tag="Smed_3644"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20479 putative dipeptide ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312390.1"
                     /db_xref="GI:150375794"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318186"
                     /translation="MTGAAIQVRDLSKTFGGGRNLFGKARHEIEAVKAVSLHVARGET
                     LAIVGESGSGKSTLARMLVGLEEPTSGSMLIGGRDAGALRRSGPRAFGRTIQYVFQDP
                     VASLNPRKTIREILDTPLTRLCGYEAPRRRARMQELLHAVQMPEDTLSRYPHEFSGGQ
                     AQRIAIARALATEAEIIVLDEPVSALDVSIQAQVLLLLRDLKNRFGLSYLFISHDLAV
                     VEAISDRVAVMYFGEVVETAPAARLFTDPEHAYTRRLVASAPRIRKE"
     misc_feature    complement(80628..81410)
                     /locus_tag="Smed_3644"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     system, ATPase component [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppF; COG1124"
                     /db_xref="CDD:224049"
     misc_feature    complement(80709..81407)
                     /locus_tag="Smed_3644"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    complement(81255..81278)
                     /locus_tag="Smed_3644"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(order(80781..80783,80880..80885,81123..81125,
                     81252..81260,81264..81269))
                     /locus_tag="Smed_3644"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(81123..81134)
                     /locus_tag="Smed_3644"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(80928..80957)
                     /locus_tag="Smed_3644"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(80880..80897)
                     /locus_tag="Smed_3644"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(80862..80873)
                     /locus_tag="Smed_3644"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(80775..80795)
                     /locus_tag="Smed_3644"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(<80628..80720)
                     /locus_tag="Smed_3644"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     gene            complement(81422..83221)
                     /locus_tag="Smed_3645"
                     /db_xref="GeneID:5318187"
     CDS             complement(81422..83221)
                     /locus_tag="Smed_3645"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component; ABC transporter related;
                     Oligopeptide/dipeptide ABC transporter domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20478 putative dipeptide ABC transporter
                     permease and ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312391.1"
                     /db_xref="GI:150375795"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013563"
                     /db_xref="GeneID:5318187"
                     /translation="MSTLAAAPAPQAGSARITSWRLLVNNRLATAGLVLLGTILLLTA
                     LAPILPLPDPNATAPADRLKPVLTAGHLLGTDQLGRDILSRLLWGTRVSVAVGFAATF
                     IAAGIGSAIGIVAGYAGGRIDNAMMRGIDMLMAFPYILLALAIVAALGPGLMNALYAI
                     ALVNIPFFARNVRGVTLGYAHREFVDAARLSGKGHLSIILTEVLPNVMPVIVITMSTT
                     AGWMILETAGLSFLGLGAQPPQADLGSMLGEGRAQIFTAPHVSIVPGVMIFLIVISLN
                     VLGDGIRDVLDPRLRSGALARPGPVTEVARDRTAPASTADDAVLVIEKLETGFRQGGE
                     FIPAVRGVSLHVKPGKCLGLIGESGSGKSVTALSVMGLVASPPGVIRNGAVYVGNEDV
                     LSMPETRLIAKRGSRVAYVFQDPLTTLHPMVAIGRQVEESIAAHQSISAADCRKKAIE
                     LLEKVGIPDARARSVHYPHQLSGGQRQRVGIAMALANDPEIIIADEPTTALDVTVQAR
                     ILELLRDLQRERGMALLFITHDFGIVSEFCDRVAVMKDGEIVETGETRQVLADPQHAY
                     TKRLIACVPELGTGARFLDRVATLFAEDKKEVA"
     misc_feature    complement(82361..83065)
                     /locus_tag="Smed_3645"
                     /note="nickel ABC transporter, permease subunit NikC;
                     Region: nickel_nikC; TIGR02790"
                     /db_xref="CDD:131837"
     misc_feature    complement(82388..82861)
                     /locus_tag="Smed_3645"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(82388..82393,82400..82405,82412..82417,
                     82421..82426,82433..82438,82466..82471,82529..82534,
                     82541..82552,82571..82573,82580..82585,82625..82627,
                     82676..82678,82685..82690,82700..82702,82706..82711,
                     82718..82720,82724..82726,82730..82735,82808..82810,
                     82811..82831,82835..82846))
                     /locus_tag="Smed_3645"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(82535..82552,82808..82810,82811..82828))
                     /locus_tag="Smed_3645"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(82436..82438,82466..82468,82475..82477,
                     82532..82534,82748..82750,82808..82810))
                     /locus_tag="Smed_3645"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(82604..82606,82616..82621,82637..82675))
                     /locus_tag="Smed_3645"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(81563..82267)
                     /locus_tag="Smed_3645"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    complement(81491..82264)
                     /locus_tag="Smed_3645"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     system, ATPase component [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppF; COG1124"
                     /db_xref="CDD:224049"
     misc_feature    complement(82133..82156)
                     /locus_tag="Smed_3645"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(order(81635..81637,81734..81739,81983..81985,
                     82130..82138,82142..82147))
                     /locus_tag="Smed_3645"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(81983..81994)
                     /locus_tag="Smed_3645"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(81782..81811)
                     /locus_tag="Smed_3645"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(81734..81751)
                     /locus_tag="Smed_3645"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(81716..81727)
                     /locus_tag="Smed_3645"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(81629..81649)
                     /locus_tag="Smed_3645"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(<81476..81574)
                     /locus_tag="Smed_3645"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     gene            complement(83218..84165)
                     /locus_tag="Smed_3646"
                     /db_xref="GeneID:5318393"
     CDS             complement(83218..84165)
                     /locus_tag="Smed_3646"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20477 putative didpeptide ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312392.1"
                     /db_xref="GI:150375796"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318393"
                     /translation="MPSYVLTRLIAVVPVLFGLSIIVFLVMTLIPGDAATAILGSYAT
                     PENVERINRDLGLDKPLVQQYVIWMGNVLQGDFGRSFALNRPVLDEVLERFQATLVLA
                     GVSLVVCSLIGLLAGVISAVRQFGWADRIITFFVLAGISMPSFWLGLLLIYLFAVHWR
                     ILPASGMYAVYGGGDLKDLLLHLILPATTLAVVAAGVIARLTRGAMLEVLRQDYVRTA
                     RAKGLPERRVIYAHAFRAALVSVIPAIGIQAGFVLGGAVYVETVFQWPGIGAMLVKAI
                     SARDILLVQGGVLVVAASYVLFNLLADVVQSMLDPRIRT"
     misc_feature    complement(83221..84165)
                     /locus_tag="Smed_3646"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppB; COG0601"
                     /db_xref="CDD:223674"
     misc_feature    complement(83332..83883)
                     /locus_tag="Smed_3646"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(83353..83358,83383..83388,83395..83406,
                     83425..83427,83434..83439,83479..83481,83530..83532,
                     83539..83544,83554..83556,83560..83565,83572..83574,
                     83578..83580,83584..83589,83710..83712,83716..83721,
                     83728..83757,83761..83772,83803..83805,83818..83823,
                     83830..83835))
                     /locus_tag="Smed_3646"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(83389..83406,83710..83754))
                     /locus_tag="Smed_3646"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(83353..83355,83362..83364,83386..83388,
                     83656..83658,83710..83712))
                     /locus_tag="Smed_3646"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(83458..83460,83470..83475,83491..83529))
                     /locus_tag="Smed_3646"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(84241..85770)
                     /locus_tag="Smed_3647"
                     /db_xref="GeneID:5318394"
     CDS             complement(84241..85770)
                     /locus_tag="Smed_3647"
                     /EC_number="3.1.3.26"
                     /note="PFAM: extracellular solute-binding protein family
                     5;
                     KEGG: sme:SMb20476 putative ABC transporter periplasmic
                     dipeptide-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="4-phytase"
                     /protein_id="YP_001312393.1"
                     /db_xref="GI:150375797"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="GeneID:5318394"
                     /translation="MVLAALAFAGTAGAQTPPDVLVVGQIAEPQSLDPHTVTATNDFR
                     ILVNVYDGLVRFKDGTLEVEPALAESWEISEDGKTYTFKLRQGVKFHDGSDFNAEAVK
                     FNFDRMLKKDHPFYGTGPFPLSFNFSSVDSVNVLDEHTVEFKLSEAFAPFLSNLAYPT
                     GLIVSPAAVSEHGKEYGRSPSGTGAFKFVEWLSNQRVVVERNPDYWDGAAKLQAVVFR
                     PITDANTRVAEMMAGGIDVMVEVPPDNLATFRQDANFAVAEQAGPHVWFAILNTKEGP
                     FADKRVRQAANYAVNKETLANDVLQGTATVAAGPIPPAFNWVESSVKPYAYDPEQAKS
                     LLAEAGVENPQVTFYVTEGGSGMLDPITMGAAIQADLQAVGFKVKIETYEWNTFLGRV
                     NPGLQGKADMAEMAWMTNDPDTVPYLTLRTDAMPDKGGFNSGYYSNPKLDELLEKARK
                     STDQAERGKLYGEVQSIVHDDAPWLFVANWKQNAVTTAAVKGFELQPSFLLDLHGVTK
                     E"
     misc_feature    complement(84244..85728)
                     /locus_tag="Smed_3647"
                     /note="ABC-type dipeptide transport system, periplasmic
                     component [Amino acid transport and metabolism]; Region:
                     DdpA; COG0747"
                     /db_xref="CDD:223818"
     misc_feature    complement(84292..85713)
                     /locus_tag="Smed_3647"
                     /note="The substrate-binding component of an ABC-type
                     dipeptide import system contains the type 2 periplasmic
                     binding fold; Region: PBP2_DppA_like; cd08493"
                     /db_xref="CDD:173858"
     misc_feature    complement(order(84547..84558,84604..84606,84616..84618))
                     /locus_tag="Smed_3647"
                     /note="peptide binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:173858"
     gene            complement(86016..86336)
                     /locus_tag="Smed_3648"
                     /db_xref="GeneID:5318395"
     CDS             complement(86016..86336)
                     /locus_tag="Smed_3648"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312394.1"
                     /db_xref="GI:150375798"
                     /db_xref="GeneID:5318395"
                     /translation="MSSRTTSEERSIWRHVESRAPHSSRRRSISDTFFVKPSTGAVYD
                     HVPEKRADIGGELFSAALDVEAEGAGAEAAMLAAALSHRFAINAYAQSAHPKFIDHND
                     SSSD"
     gene            86646..86996
                     /locus_tag="Smed_3649"
                     /db_xref="GeneID:5318396"
     CDS             86646..86996
                     /locus_tag="Smed_3649"
                     /note="KEGG: bur:Bcep18194_B1716 membrane protein-like"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312395.1"
                     /db_xref="GI:150375799"
                     /db_xref="GeneID:5318396"
                     /translation="MAGLLISGYSPGLLIAVASLGNVLASVMNWGLGRGIEHFRDRRW
                     FPVRDAGLERAQHWYRRYGKWSLLLSWVPVVGDPLTVVAGIMKEPLLPFLLLVAIAKS
                     ARHLVVGPVTLNWA"
     sig_peptide     86646..86723
                     /locus_tag="Smed_3649"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.643) with cleavage site probability 0.606 at
                     residue 26"
     misc_feature    <86649..86990
                     /locus_tag="Smed_3649"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG1238"
                     /db_xref="CDD:224159"
     gene            87250..88071
                     /locus_tag="Smed_3650"
                     /db_xref="GeneID:5318397"
     CDS             87250..88071
                     /locus_tag="Smed_3650"
                     /note="SMART: Rhodanese domain protein;
                     KEGG: ret:RHE_CH02717 putative superoxide dismutase
                     SodM-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese domain-containing protein"
                     /protein_id="YP_001312396.1"
                     /db_xref="GI:150375800"
                     /db_xref="InterPro:IPR001763"
                     /db_xref="GeneID:5318397"
                     /translation="MSSHLEIAPEKLARLIGTPKCPALIDVRVGEDFDEDPRLVPGSI
                     RRDYRKVQEWATELGGTSAVVVCHRGKKLSYGVAAWLRNYGIAADVLEGGVAAWTEGG
                     YPTVPISAIPERDASGRTVWVTRARPKIDRIACPWLIRRFVDPLAVFLYVAPSEVEAV
                     AERFAATPFDMDAPIRWSHRGELCTFDIMVEEFGLSIEPLLRLATIVRGADTSRLDLA
                     PQASGLLAASLGLSRMYADDLEQLEAGMALYDAFYRWCRDATDETHNWPSPKKDS"
     misc_feature    87265..87549
                     /locus_tag="Smed_3650"
                     /note="Rhodanese Homology Domain (RHOD); an alpha beta
                     fold domain found duplicated in the rhodanese protein. The
                     cysteine containing enzymatically active version of the
                     domain is also found in the Cdc25 class of protein
                     phosphatases and a variety of proteins...; Region: RHOD;
                     cl00125"
                     /db_xref="CDD:241626"
     misc_feature    87448..87450
                     /locus_tag="Smed_3650"
                     /note="active site residue [active]"
                     /db_xref="CDD:238089"
     misc_feature    87613..88020
                     /locus_tag="Smed_3650"
                     /note="Chromate resistance exported protein; Region:
                     Chrome_Resist; pfam09828"
                     /db_xref="CDD:150492"
     gene            88071..89480
                     /locus_tag="Smed_3651"
                     /db_xref="GeneID:5318398"
     CDS             88071..89480
                     /locus_tag="Smed_3651"
                     /note="TIGRFAM: chromate transporter, chromate ion
                     transporter (CHR) family;
                     PFAM: Chromate transporter;
                     KEGG: rle:RL3184 putative chromate transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="YP_001312397.1"
                     /db_xref="GI:150375801"
                     /db_xref="InterPro:IPR003370"
                     /db_xref="InterPro:IPR014047"
                     /db_xref="GeneID:5318398"
                     /translation="MSEITNSALPDTARQDYGHGIPFGEAVRVWARIAALSFGGPAGQ
                     IAVMHRILVDEKRWIGEHRFLHALNYCMLLPGPEAQQLAVYIGWLLHRTAGGLVAGTL
                     FVLPGFLAILGLSYIYAAFGNVSIVEGLFFGLKAAVLAVVVHAVFRIGSRALKNYLMV
                     GIAAAAFIGIFFFRVPFPLIILAAGICGYIGGRSGSPLFRIGGGHKAGSGAILRDEDS
                     LLGEETPAHARPNLSWSLRISAVFFAIWLVPLMLLTAFLGIDNVFTQIGLFFSQMAVV
                     TFGGAYAVLAYVAQEAVQHYGWLKPGEMLDGLGMAETTPGPLIMVVQFVGFMGAFRDP
                     GSLNPMTAATLAAILTTWVTFVPCFLWIFLGAPFIERLRNNVALTGAMSAITAAVVGV
                     ILNLAVWFGLHTLFSEVVTWRLGWFALDVPDPASLVLPSLVLTAAAAIAIFRYQASII
                     ATLLACAVAGLVWSLIAGA"
     misc_feature    88125..88649
                     /locus_tag="Smed_3651"
                     /note="Chromate transport protein ChrA [Inorganic ion
                     transport and metabolism]; Region: ChrA; COG2059"
                     /db_xref="CDD:224970"
     misc_feature    88863..>89291
                     /locus_tag="Smed_3651"
                     /note="Chromate transporter; Region: Chromate_transp;
                     pfam02417"
                     /db_xref="CDD:217024"
     gene            complement(89709..90518)
                     /locus_tag="Smed_3652"
                     /db_xref="GeneID:5318399"
     CDS             complement(89709..90518)
                     /locus_tag="Smed_3652"
                     /note="PFAM: NAD-dependent epimerase/dehydratase;
                     short-chain dehydrogenase/reductase SDR; KR domain
                     protein;
                     KEGG: bsu:BG10628 similar to glucose 1-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001312398.1"
                     /db_xref="GI:150375802"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR002424"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5318399"
                     /translation="MADFSGKTVLVTGGAGVIGKSAAKLFLERGANVVLADIDAGKLE
                     TAAEALNGGERVSTIPGDLSETETAKAAVDHAVGVYGKLDILFNNAGISGKVAPVHLL
                     DVDAWDDIVKVNLRSMFLMLKFAASNMVARKSGSIINMASSMSGWDVLSGGAGYASTK
                     HGVVGLTKVAALDLARYRIRVNAICPGVIETTLGVPGLGEDKGSSAVEHFADRIPLRR
                     IGQPADVAEVVLFLASDAARHVNGAAWLIDGGQTLQSFSNAPEEGVYPLES"
     misc_feature    complement(89760..90512)
                     /locus_tag="Smed_3652"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Validated; Region: fabG; PRK05653"
                     /db_xref="CDD:235546"
     misc_feature    complement(89775..90494)
                     /locus_tag="Smed_3652"
                     /note="classical (c) SDRs; Region: SDR_c; cd05233"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(89943..89948,89952..89963,90039..90041,
                     90051..90053,90090..90095,90099..90101,90180..90182,
                     90246..90254,90330..90338,90402..90410,90465..90476,
                     90480..90482))
                     /locus_tag="Smed_3652"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(90039..90041,90051..90053,90090..90092,
                     90177..90179))
                     /locus_tag="Smed_3652"
                     /note="active site"
                     /db_xref="CDD:212491"
     gene            complement(90568..91407)
                     /locus_tag="Smed_3653"
                     /db_xref="GeneID:5318400"
     CDS             complement(90568..91407)
                     /locus_tag="Smed_3653"
                     /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase;
                     dTDP-4-dehydrorhamnose reductase; Male sterility domain;
                     KEGG: rxy:Rxyl_0938 NAD-dependent epimerase/dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="YP_001312399.1"
                     /db_xref="GI:150375803"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318400"
                     /translation="MAGRKHVVVTGAAGLLGRHVAGAYRQAGFAVTALDHEPRGLEDV
                     IGADLMDPDVARRHIADADLVAHIASIPRPVGYDAGQVFQTNMTLMFNVLAATEAAGI
                     SRLLFASSFSVLGLPFAPRPVELNYLPVDEHHPAQPQDVYAVTKWLGEEMVDAWTRRI
                     GGSAISLRMPWIQTPESFMFEVAKRRLTEEAALDLWAYIDARDAARAFLLAANAQTPG
                     HERFFISAGDSYSETPTADLLAARYPGTQVRTSLEGHAGLLSNDRAKHLIDFVPRYSW
                     RDY"
     misc_feature    complement(<90892..91395)
                     /locus_tag="Smed_3653"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    complement(<90904..91392)
                     /locus_tag="Smed_3653"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    complement(order(90970..90972,90982..90984,91078..91086,
                     91201..91206,91300..91305,91360..91362,91366..91371,
                     91375..91377))
                     /locus_tag="Smed_3653"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    complement(order(90970..90972,90982..90984,91078..91080,
                     91150..91152))
                     /locus_tag="Smed_3653"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            91607..92611
                     /locus_tag="Smed_3654"
                     /db_xref="GeneID:5318401"
     CDS             91607..92611
                     /locus_tag="Smed_3654"
                     /note="PFAM: basic membrane lipoprotein;
                     KEGG: rxy:Rxyl_0155 basic membrane lipoprotein"
                     /codon_start=1
                     /transl_table=11
                     /product="basic membrane lipoprotein"
                     /protein_id="YP_001312400.1"
                     /db_xref="GI:150375804"
                     /db_xref="InterPro:IPR003760"
                     /db_xref="GeneID:5318401"
                     /translation="MNTAFKRILAGPVVAAAVACGSGAAQAEPLKIAAVSGYFSQGFG
                     ISIVNGLERAKKDLGVELKIVDTGNRALDYEEQFNNLAKGGQYDLIFVMGWELVDALQ
                     KSNKTYPDQRFIFIDGVLDSPTMTYIDFVEEEGSFLAGALAGMLTQEKVEGFDSSSEV
                     GFLGGRDIPVIRNFMSGMEQGVAKVASDVTVNGVFAGTFDDPAKGSELAMTLYGQGVD
                     IIYQAAGPTGEGVLQAAKAARKYAIGVDIDQCGTAPGAILASMLKRADVAVYELIKGE
                     AEGNKIKPGAVAFGVKAGGVELKICDEVKDKVPAEIVAKLEELRQGVADGSVAVKLNQ
                     "
     sig_peptide     91607..91690
                     /locus_tag="Smed_3654"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.993 at
                     residue 28"
     misc_feature    91688..92608
                     /locus_tag="Smed_3654"
                     /note="Uncharacterized ABC-type transport system,
                     periplasmic component/surface lipoprotein [General
                     function prediction only]; Region: Med; COG1744"
                     /db_xref="CDD:224658"
     misc_feature    91709..92458
                     /locus_tag="Smed_3654"
                     /note="Periplasmic binding domain of basic membrane
                     lipoprotein, PnrA, in Treponema pallidum and its homologs
                     from other bacteria and Archaea; Region:
                     PBP1_BmpA_PnrA_like; cd06354"
                     /db_xref="CDD:107349"
     misc_feature    order(91709..91711,91736..91738,91955..91957,92117..92119,
                     92201..92203,92279..92281,92342..92344,92393..92395)
                     /locus_tag="Smed_3654"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107349"
     gene            92760..94289
                     /locus_tag="Smed_3655"
                     /db_xref="GeneID:5318669"
     CDS             92760..94289
                     /locus_tag="Smed_3655"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: bsu:BG12350 simple sugar transport system
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312401.1"
                     /db_xref="GI:150375805"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318669"
                     /translation="MTYAIEMQAITKRFGTLAANKDVTFSVRRGEIHALVGENGAGKT
                     TLMNVLFGLHQPDEGVLAINGRTVKMDSPRTAIALGLGMVHQHFKLVPSLTVAENIFL
                     GMEMTRNGLIDRKAQSAKVAELSSAFGLHVDPERRVMDLSVGIEQRVEILKVLVRGAE
                     IIILDEPTAVLTPQESRDLFRILRSFTEKGMTVVFISHHLTEVMEVSDTVTVLRDGQV
                     VGTKPTRELTEDELVRMMVGRDVSFARRERQPANGGTVLNLSEVCARDDRGLPTLRDV
                     SVEVRAGEIVGVVGVDGNGQTELAEVISGLRPVSYGTISLAGTALENADPLTIRKSGL
                     SHVPGNRLARGVDASASIASNILMGRHQTAPWVRRGIVRWSYVREQAGKLIRQFEIRA
                     SSERALVKTLSGGNMQKVVLAREFSQNMPFLLIDQPTRGVDIGAMEGIHDEIMRQRNS
                     GAAILLISVQLDEILKLADRILVMFGGRIVGEVDPESTTEDEIGFLMAGRASSEAKVA
                     S"
     misc_feature    92760..94256
                     /locus_tag="Smed_3655"
                     /note="ABC-type uncharacterized transport systems, ATPase
                     components [General function prediction only]; Region:
                     COG3845"
                     /db_xref="CDD:226364"
     misc_feature    92772..93422
                     /locus_tag="Smed_3655"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    92868..92891
                     /locus_tag="Smed_3655"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(92877..92882,92886..92894,93015..93017,93252..93257,
                     93351..93353)
                     /locus_tag="Smed_3655"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    93006..93017
                     /locus_tag="Smed_3655"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(93039..93053,93195..93209)
                     /locus_tag="Smed_3655"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    93240..93257
                     /locus_tag="Smed_3655"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    93264..93275
                     /locus_tag="Smed_3655"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    93339..93359
                     /locus_tag="Smed_3655"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    93549..94196
                     /locus_tag="Smed_3655"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            94286..95383
                     /locus_tag="Smed_3656"
                     /db_xref="GeneID:5318670"
     CDS             94286..95383
                     /locus_tag="Smed_3656"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20126 putative sugar ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="YP_001312402.1"
                     /db_xref="GI:150375806"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="InterPro:IPR002110"
                     /db_xref="GeneID:5318670"
                     /translation="MTTDSSATKSSVVPAADRKGPPGWAEGLIGQLLAIALSLVGGAV
                     IILMVGENPLHVFATLLRGAFGSTDRIAGSLLQATPIIICGVAACIALRGGLFNIGVE
                     GQLYLGGFAAAWVGFSFAMPPVIHVVVAVAAAILAGCLWILIPALFRAKFGTNEVVTT
                     ILANYIAVLLTSYLTISVFKRPGGWSETDPIAVTARLPQLLPDSRLNIGLFIGIGLAI
                     GLHLFLRHTSAGYAMGAMGANPKFAEYGGVRTRRNVFLILLASGAVGGLAGGVETLGV
                     HHRFMEGFAPGFGFDGVIAALLANGNPIGMIGTALFFGALRAGSLLMEVETNASREII
                     TVIQAFIILCVSAQILIRRRSGRTGERRWKF"
     misc_feature    94496..95320
                     /locus_tag="Smed_3656"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    94517..95323
                     /locus_tag="Smed_3656"
                     /note="Transmembrane subunit (TM) of Treponema pallidum
                     (Tp) RbsC-1, RbsC-2 and related proteins. This is a
                     functionally uncharacterized subgroup of TMs which belong
                     to a larger group of TMs of Periplasmic Binding Protein
                     (PBP)-dependent ATP-Binding Cassette; Region:
                     TM_PBP1_transp_TpRbsC_like; cd06580"
                     /db_xref="CDD:119322"
     misc_feature    95006..95062
                     /locus_tag="Smed_3656"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119322"
     gene            95371..96318
                     /locus_tag="Smed_3657"
                     /db_xref="GeneID:5318671"
     CDS             95371..96318
                     /locus_tag="Smed_3657"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sma:SAV6654 putative sugar ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="YP_001312403.1"
                     /db_xref="GI:150375807"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318671"
                     /translation="MEVLEKIFNFALIAATLRTTAPILLVSLGGSFTTKAGIFNIGLE
                     GQMLVGAFFGVLGSIWTGSALGGLLCGVLAAVVMAATFSLLVVTLRANEVVVGLALNI
                     LAGGLTISLTKAIFGTRGSIVSGDIVGLPPIDIPFIEDLGRFGRVLSGYTPLVYLAFV
                     MVFVVWLVLYRTKLGLYIRVTGEKPEAAEALGIPTALMQHIASLLCGVLAGLAGAHLS
                     LGYITMFAENMSSGRGFMAVAVLIFSNGDPLKVLLGCLLFGFSDAASLRLQTFGFPSY
                     IVLMVPYLVTLGALFALTYRQRPKVIRETLESLSLLRRT"
     misc_feature    95404..96240
                     /locus_tag="Smed_3657"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    95428..96240
                     /locus_tag="Smed_3657"
                     /note="Transmembrane subunit (TM) of Treponema pallidum
                     (Tp) RbsC-1, RbsC-2 and related proteins. This is a
                     functionally uncharacterized subgroup of TMs which belong
                     to a larger group of TMs of Periplasmic Binding Protein
                     (PBP)-dependent ATP-Binding Cassette; Region:
                     TM_PBP1_transp_TpRbsC_like; cd06580"
                     /db_xref="CDD:119322"
     misc_feature    95926..95982
                     /locus_tag="Smed_3657"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119322"
     gene            96333..97337
                     /locus_tag="Smed_3658"
                     /db_xref="GeneID:5318672"
     CDS             96333..97337
                     /locus_tag="Smed_3658"
                     /note="PFAM: Inosine/uridine-preferring nucleoside
                     hydrolase;
                     KEGG: bcl:ABC3205 inosine-uridine preferring nucleoside
                     hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/uridine-preferring nucleoside hydrolase"
                     /protein_id="YP_001312404.1"
                     /db_xref="GI:150375808"
                     /db_xref="InterPro:IPR001910"
                     /db_xref="GeneID:5318672"
                     /translation="MERIILDVDSAGDDILAILFSAGCADTKLEGVTTVAGAAGGIEQ
                     VTNVVLNTLTLAGRNDIPVAAGAYRPIVGNAKADMEAPVHFEKQLQARFGDRLQGFNP
                     PAPEPACKAMGKHAIDFIVDTVRANPGEVSIVATGPQTNVALALQMAPDIARLVKQIV
                     VLGGCFQTPGNMTPVSEYNIWADPEAARVVLRSGAPVILVPLDVCEDNRVAASMLTRD
                     DLNDLASLYPASKAVSYVCETFPIYIDIWREFFELVGFPLDDAIAVVAVLHPEFFEMT
                     EPLFVDVALSERLVRGQTVAFQGRQILPFSGPKTTRVCRNLDGRKFLSLFKNSIGSLS
                     "
     misc_feature    96339..97334
                     /locus_tag="Smed_3658"
                     /note="Inosine-uridine preferring nucleoside hydrolase;
                     Region: IU_nuc_hydro; pfam01156"
                     /db_xref="CDD:216336"
     misc_feature    order(96357..96359,96369..96374,96444..96446,96738..96740,
                     96843..96845,96861..96863,96867..96869,97110..97112)
                     /locus_tag="Smed_3658"
                     /note="active site"
                     /db_xref="CDD:238257"
     gene            97334..98275
                     /locus_tag="Smed_3659"
                     /db_xref="GeneID:5318673"
     CDS             97334..98275
                     /locus_tag="Smed_3659"
                     /note="PFAM: Inosine/uridine-preferring nucleoside
                     hydrolase;
                     KEGG: ppr:PBPRA2062 putstive inosine-uridine preferring
                     nucleoside hydrolase family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/uridine-preferring nucleoside hydrolase"
                     /protein_id="YP_001312405.1"
                     /db_xref="GI:150375809"
                     /db_xref="InterPro:IPR001910"
                     /db_xref="GeneID:5318673"
                     /translation="MSKTVKTIPVLMDCDPGHDDAIALVMAHRSPVIDLLGVTTVCGN
                     APPERTTSNALRIMQFIDATDVPVAQGCVTPLARPLVLGTADGPTGLDGTTYLPEATM
                     PLVPMHGVDFIAKILREAPEPVVLVPTGPLTNIAMFLLKYPELKHKIDKIVLMGGAFY
                     RRTEYITPTEFNIFCDPEAARIVLDSGLDIIMVGLDVTMHVLVEEEQFAELRKIESPL
                     GKVVLDWLKFYEKLHRGQMGVGGALHDPLALAAVIDPTLIETREAHVEIDLTGTYTFG
                     ATVADFWNERKLGNNTRIATRVDSGRFFELMYSLLRD"
     misc_feature    97358..98266
                     /locus_tag="Smed_3659"
                     /note="nuc_hydro_IU_UC_XIUA: inosine-uridine preferring,
                     xanthosine-inosine-uridine-adenosine-preferring and,
                     uridine-cytidine preferring nucleoside hydrolases.
                     Nucleoside hydrolases cleave the N-glycosidic bond in
                     nucleosides generating ribose and the...; Region:
                     nuc_hydro_IU_UC_XIUA; cd02651"
                     /db_xref="CDD:239117"
     misc_feature    order(97376..97378,97388..97393,97463..97465,97718..97720,
                     97826..97828,97841..97843,97847..97849,98066..98068)
                     /locus_tag="Smed_3659"
                     /note="active site"
                     /db_xref="CDD:239117"
     misc_feature    order(97559..97561,97751..97753,97877..97879,98135..98137,
                     98141..98146,98153..98155)
                     /locus_tag="Smed_3659"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239117"
     gene            98320..98961
                     /locus_tag="Smed_3660"
                     /db_xref="GeneID:5318674"
     CDS             98320..98961
                     /locus_tag="Smed_3660"
                     /note="PFAM: isochorismatase hydrolase;
                     KEGG: chy:CHY_0679 isochorismatase family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase hydrolase"
                     /protein_id="YP_001312406.1"
                     /db_xref="GI:150375810"
                     /db_xref="InterPro:IPR000868"
                     /db_xref="InterPro:IPR003881"
                     /db_xref="GeneID:5318674"
                     /translation="MDDVFSAHRRNEDAVLDPAKTAVIVVDMINEFCKPGGRMVLPGY
                     EALMPAQKALVAAARSNGVPVIWVVDSHRKNMRRDREWVKRTPHCVENTWATEVIDDL
                     EPQETDITVVKHRYSAFFQTDLDLVLKDMLIGQIVVFGVVTNICVRSTVHDGFFLGYD
                     IVVPHDACAATGAREHASTLYDIATHFGTVSDAATIAAAIAGGVAIPNQVFEG"
     misc_feature    98380..98895
                     /locus_tag="Smed_3660"
                     /note="Isochorismatase family; Region: Isochorismatase;
                     pfam00857"
                     /db_xref="CDD:216156"
     misc_feature    98383..98871
                     /locus_tag="Smed_3660"
                     /note="Cysteine hydrolases; This family contains
                     amidohydrolases, like CSHase (N-carbamoylsarcosine
                     amidohydrolase), involved in creatine metabolism and
                     nicotinamidase, converting nicotinamide to nicotinic acid
                     and ammonia in the pyridine nucleotide cycle. It...;
                     Region: cysteine_hydrolases; cd00431"
                     /db_xref="CDD:238245"
     misc_feature    order(98398..98400,98656..98658,98755..98757)
                     /locus_tag="Smed_3660"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238245"
     misc_feature    98740..98745
                     /locus_tag="Smed_3660"
                     /note="conserved cis-peptide bond; other site"
                     /db_xref="CDD:238245"
     gene            98966..99484
                     /locus_tag="Smed_3661"
                     /db_xref="GeneID:5318675"
     CDS             98966..99484
                     /locus_tag="Smed_3661"
                     /note="PFAM: regulatory protein MarR;
                     KEGG: mag:amb1485 transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="YP_001312407.1"
                     /db_xref="GI:150375811"
                     /db_xref="InterPro:IPR000835"
                     /db_xref="GeneID:5318675"
                     /translation="MRKLHHMNRKKEQASPGEELSPRLSQTEIDKRLVEIGYRLEAHN
                     AHLIRLAHQRATSLFQKAFENYTITPTQVAILATLLRHGDLSQINLGRLTAIDTATLS
                     AMMRRLQDNGFIERIPSEQDQRVNLVRLTARGIEFTLEVLPISQKVSDEVLAPLKPRD
                     RERFIEMLKLLG"
     misc_feature    99146..99448
                     /locus_tag="Smed_3661"
                     /note="helix_turn_helix multiple antibiotic resistance
                     protein; Region: HTH_MARR; smart00347"
                     /db_xref="CDD:197670"
     misc_feature    99167..99340
                     /locus_tag="Smed_3661"
                     /note="MarR family; Region: MarR; pfam01047"
                     /db_xref="CDD:201571"
     gene            99529..100113
                     /locus_tag="Smed_3662"
                     /db_xref="GeneID:5318676"
     CDS             99529..100113
                     /locus_tag="Smed_3662"
                     /note="PFAM: protein of unknown function DUF1185;
                     KEGG: mlo:mll4877 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312408.1"
                     /db_xref="GI:150375812"
                     /db_xref="InterPro:IPR009569"
                     /db_xref="GeneID:5318676"
                     /translation="MPQFIVRKSITLVEDIFHDGGPVATVPRRRAAAVAIVSNPFAGR
                     YVEDLQPAMEDLKPLGLRMTDNLVGALGGDTSLIDGYGKGVIVGSAGELEHGALWHVP
                     GGYAMRERLGEALAIVPSAKKVGGFGARIDIPIGHKNAAYVRSHFDAMEIGVPDGPRP
                     DELLLCLVMTCGPRIHARMGGLAASDIKAFDGLR"
     misc_feature    99544..100068
                     /locus_tag="Smed_3662"
                     /note="Amino acid synthesis; Region: AA_synth; pfam06684"
                     /db_xref="CDD:219135"
     gene            complement(100349..102109)
                     /locus_tag="Smed_3663"
                     /db_xref="GeneID:5318677"
     CDS             complement(100349..102109)
                     /locus_tag="Smed_3663"
                     /EC_number="3.5.2.9"
                     /note="PFAM: Hydantoinase B/oxoprolinase;
                     KEGG: mlo:mlr4788 N-methylhydantoinase B"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase"
                     /protein_id="YP_001312409.1"
                     /db_xref="GI:150375813"
                     /db_xref="InterPro:IPR003692"
                     /db_xref="GeneID:5318677"
                     /translation="MSTIDPITLTVIQSGLQQVCDEMDMTFSRAAFSPIIAEADDRSD
                     GIYSAEDGSLIAQGIKGLPVFVGTMQASTRTLIEFIRDGRCLPPEEDDIYAVNDPYLG
                     GTHLMDVRFATPFYRNGEIFCWLSNIGHWPDIGGAVPGGFSASATSVEQEGLRFPPIK
                     LFKRGVLDRELFSIISSNIRVAEQRIGDIRAQAAALRVGKEQFTALLDRYGDDTVAAA
                     IAELRRRSAAQMRASIRTIAPGTYHGKAFIDSDGVVNEPLTIALSVTKTGDDRLVFDF
                     AGSSPPCRGPMNCVLATTHSSVYLAMRHIFPEIPLSAGAFEPLEIVSPAGTFLDAQYP
                     RPVSGCAAEVSQRIAEAVFSALVQALPERVTAAPAGSSGNFALGGSDPLLGRDYVMYH
                     ISGGGYGGNAREDGLTNGCSTIGISKSAPVEITEQVFPVFFREYAIHEGSGGAGRNRG
                     GFGLSYEVELLRGDAQASFVMDHGAFGPQGALGGADGAVGTITVTRGGKTYRPEHLSK
                     EQDIALTAGDRVRVETPGGGGYGLAHERDVEAVLKDVFLGYYSLQQAESLFGVVIDTT
                     SGKLDREATEKLRRRRSKGA"
     misc_feature    complement(100373..102100)
                     /locus_tag="Smed_3663"
                     /note="N-methylhydantoinase B/acetone carboxylase, alpha
                     subunit [Amino acid transport and metabolism / Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: HyuB; COG0146"
                     /db_xref="CDD:223224"
     misc_feature    complement(100478..102100)
                     /locus_tag="Smed_3663"
                     /note="Hydantoinase B/oxoprolinase; Region:
                     Hydantoinase_B; pfam02538"
                     /db_xref="CDD:217092"
     gene            complement(102106..104181)
                     /locus_tag="Smed_3664"
                     /db_xref="GeneID:5318678"
     CDS             complement(102106..104181)
                     /locus_tag="Smed_3664"
                     /EC_number="3.5.2.9"
                     /note="PFAM: Hydantoinase/oxoprolinase;
                     Hydantoinaseoxoprolinase domain protein;
                     KEGG: mlo:mlr4786 N-methylhydantoinase A
                     (mikimopine-lactam hydrogenase)"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase"
                     /protein_id="YP_001312410.1"
                     /db_xref="GI:150375814"
                     /db_xref="InterPro:IPR002821"
                     /db_xref="InterPro:IPR008040"
                     /db_xref="GeneID:5318678"
                     /translation="MWSEDRERSGGTVAGVDVGGTFTDLIIVDESTGAVQIGKVPTTT
                     HDQSHGVLSALAKSSRPIASIDLIIHGTTATTNALLERRIARAGMITTKGFRDVIELG
                     RRTRPSPYGLFGTFVPVIPRNLRLEVDERIQATGEVVTPLDATGVRSAVRQLIEAGCE
                     ALVIHFLHSYKNPAHELEAAEIAREFWPNAYITTGHSLLSEAREFERGVTASVNASVQ
                     PILERYVERLRVELEKSGYSRDYLIMNGNGGTISSRLASREAAKTVMSGPASGVIAAA
                     YTAAKAGYDNLITYDMGGTSTDVALIRDNRPLVSSEIEVEYAMPIHVPMVDVHTVGAG
                     GGSIARVDEAGLLRVGPQSAGSTPGPICYGRGGVEPTISDANIVLGRLNSKKLLAVDS
                     PVPVEMIAGAFSDRIGGRLNLDAAHAAEATVRIANMKMAGAIRMVSIAKGNDPRDFIL
                     FAFGGAGPLHAAAIARELGIPRVMIPARPGITNAIGCIVADLRHDYVNTVNMPLLDSD
                     PAHLNAILQQQTRAGMDAIELEAVRPERIEVEYSADMQFVGQTHLIRVPLPDAAIDLD
                     ELQARFEAAYYDRFRVRLPEVRANIVSLNCSVIGIRKAISLDDLIPNDGRCAILKEAQ
                     LEVRPVWFDGAWWDTPVYARERLPLQAEIKGPAILEQLDATTVINPGDVAKGDVHGNI
                     IITIGAPAA"
     misc_feature    complement(102121..104112)
                     /locus_tag="Smed_3664"
                     /note="N-methylhydantoinase A/acetone carboxylase, beta
                     subunit [Amino acid transport and metabolism / Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: HyuA; COG0145"
                     /db_xref="CDD:223223"
     misc_feature    complement(103627..104112)
                     /locus_tag="Smed_3664"
                     /note="Hydantoinase/oxoprolinase N-terminal region;
                     Region: Hydant_A_N; pfam05378"
                     /db_xref="CDD:218571"
     misc_feature    complement(102694..103563)
                     /locus_tag="Smed_3664"
                     /note="Hydantoinase/oxoprolinase; Region: Hydantoinase_A;
                     pfam01968"
                     /db_xref="CDD:216816"
     gene            complement(104426..105604)
                     /locus_tag="Smed_3665"
                     /db_xref="GeneID:5318062"
     CDS             complement(104426..105604)
                     /locus_tag="Smed_3665"
                     /note="PFAM: peptidase M42 family protein;
                     KEGG: sme:SMb20466 hypothetical glucanase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M42 family protein"
                     /protein_id="YP_001312411.1"
                     /db_xref="GI:150375815"
                     /db_xref="InterPro:IPR000307"
                     /db_xref="InterPro:IPR008007"
                     /db_xref="GeneID:5318062"
                     /translation="MIATTHSMQTPINIDPDYLTSRLKALLEIASPTGFTDEAVRYTA
                     RELERLGLEVKLTRRGAIRAMRPGAAERPARGIVSHLDTLGAQVKALKENGRLELVSI
                     GHWSARFAEGARGSIFSGKGTYRGTILPLKASGHTFNDEIDTQPTGWRHIELRVDALA
                     RDRSDLVQLGIDVGDIVAIDPQPEFLDNGFIVSRHLDDKAGVAIMLAALEAMQRQKVE
                     TPVDTYWLFTIGEEVGVGASAAIVPEIASLVAIDNGTTAPGQNSDEFGVTLAMADQTG
                     PFDYHLSRKLYELCGEHGIRVQKDVFRYYRSDAASALEAGHDVRTALLTFGVDASHGY
                     ERIHLHALMSVAKLAVYHAASEVQIERDAEEVSGLRGFTRQKVRQAEQDLKADEPEGP
                     "
     misc_feature    complement(104525..105556)
                     /locus_tag="Smed_3665"
                     /note="Cellulase M and related proteins [Carbohydrate
                     transport and metabolism]; Region: FrvX; COG1363"
                     /db_xref="CDD:224282"
     misc_feature    complement(104549..105553)
                     /locus_tag="Smed_3665"
                     /note="M42 Peptidase, Endoglucanase-like subfamily;
                     Region: M42_glucanase_like; cd05657"
                     /db_xref="CDD:193533"
     misc_feature    complement(order(104597..104599,104606..104608,
                     104615..104620,104666..104668,104702..104704,
                     104744..104746,104792..104794,104810..104818,
                     104885..104890,104897..104899,105029..105031,
                     105035..105037,105047..105049,105053..105055,
                     105083..105088,105134..105142,105146..105148,
                     105224..105226,105230..105235,105263..105271,
                     105305..105307,105338..105346,105425..105427,
                     105434..105439,105473..105475,105485..105487,
                     105500..105508))
                     /locus_tag="Smed_3665"
                     /note="putative oligomer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:193533"
     misc_feature    complement(order(104609..104614,104687..104692,
                     104699..104701,104840..104851,104900..104902,
                     104909..104914,105014..105016,105365..105367))
                     /locus_tag="Smed_3665"
                     /note="putative active site [active]"
                     /db_xref="CDD:193533"
     misc_feature    complement(order(104609..104611,104849..104851,
                     104909..104914,105014..105016,105365..105367))
                     /locus_tag="Smed_3665"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:193533"
     gene            105757..106824
                     /locus_tag="Smed_3666"
                     /db_xref="GeneID:5318063"
     CDS             105757..106824
                     /locus_tag="Smed_3666"
                     /note="KEGG: sme:SMb20465 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312412.1"
                     /db_xref="GI:150375816"
                     /db_xref="GeneID:5318063"
                     /translation="MGKSVNEKQSAPLIHGASDLPSVTVDGYNLELRDGDGFLGDKAN
                     KSAFQEKLDDWRKRVRKGGDDPLGEALTQDLSKKQIDALLRGDDKQAAALIMGAMDEF
                     AGELAGVLEKFLQQKSWKNSERVVIGGGFRGSAVGEFAIARAMVLMKAKGIKIELSPI
                     VHHPDDAGLIGAAHLMPAWMLKGHKTILAIDIGGTNIRVGIVELRLKDDTDLSRAKVW
                     KSDIWRHADDKPNRSATIEALIGMIEKLIAKADKADLAPAPVIGVACPGVINADGSIL
                     RGGQNLPGGNWESEHFNLPATLKDAIPQIGDHETFVIMHNDAVVQGLSQVPFVQNASS
                     WGILTIGTGLGNAHFSNKAGN"
     misc_feature    106318..>106785
                     /locus_tag="Smed_3666"
                     /note="Nucleotide-Binding Domain of the sugar
                     kinase/HSP70/actin superfamily; Region:
                     NBD_sugar-kinase_HSP70_actin; cd00012"
                     /db_xref="CDD:212657"
     misc_feature    order(106327..106338,106342..106344,106348..106350,
                     106705..106707,106771..106782)
                     /locus_tag="Smed_3666"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212657"
     gene            106996..107298
                     /locus_tag="Smed_3667"
                     /db_xref="GeneID:5318064"
     CDS             106996..107298
                     /locus_tag="Smed_3667"
                     /note="KEGG: sme:SMb20464 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312413.1"
                     /db_xref="GI:150375817"
                     /db_xref="GeneID:5318064"
                     /translation="MKVKSTARSGLFCTHRTIVRSTLAVMVAAASCGCSSTVSQETTS
                     SITREAGYSIPDQKPAPGKQAVTKKANKLVRSAYLGRAPYICTPSGFGSTSRCFLR"
     sig_peptide     106996..107115
                     /locus_tag="Smed_3667"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.822 at
                     residue 40"
     gene            complement(107432..107941)
                     /locus_tag="Smed_3668"
                     /db_xref="GeneID:5318065"
     CDS             complement(107432..107941)
                     /locus_tag="Smed_3668"
                     /note="PFAM: protein of unknown function DUF995;
                     KEGG: sme:SMb20463 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312414.1"
                     /db_xref="GI:150375818"
                     /db_xref="InterPro:IPR009337"
                     /db_xref="GeneID:5318065"
                     /translation="MKSMNRGIPLAIVLVAGLATASFAEAAAARADRKTTALTHAELF
                     QLYGQKSWIWKEGAGYFSVQARRFTAWSKENGKPSYGVGRWFITGPGKLCFRADWHAK
                     DGSAPATTCFSHRKRAGVIYQRREPDGAWYVFKNAQVRPDDEFVKLRRGNYVGARLNR
                     IEARLGGEE"
     sig_peptide     complement(107867..107941)
                     /locus_tag="Smed_3668"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.511 at
                     residue 25"
     misc_feature    complement(107477..>107824)
                     /locus_tag="Smed_3668"
                     /note="Protein of unknown function (DUF995); Region:
                     DUF995; pfam06191"
                     /db_xref="CDD:218932"
     gene            complement(107941..108918)
                     /locus_tag="Smed_3669"
                     /db_xref="GeneID:5318066"
     CDS             complement(107941..108918)
                     /locus_tag="Smed_3669"
                     /note="KEGG: sme:SMb20462 putative cellulase H precursor
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative cellulase H protein"
                     /protein_id="YP_001312415.1"
                     /db_xref="GI:150375819"
                     /db_xref="GeneID:5318066"
                     /translation="MNRKSKAVAFGCLGLLLSGTVLAANMPRGIPDENSPTKATPSDK
                     RPVLTETSLDFGAYDPHGDFGTPGSSKIEHLFLPWEDVDLSTLALADDYAQARGRSLL
                     ITIEPWSWSPEWRVTEEELLRSILSGERDQNMAQVCSAAAALKSPVIIRWGQEMDETD
                     NQFSWSHWRGEDFKAAYRHVVGVCRGHLKNAKFMWSPKGNEGLDAFYPGDDVVDIVGL
                     SVFGYQPYDEGTTGRAQTFVERLAPGYGRVMNYGKPVMVAELGYEGDGSYVASWAASV
                     AERHAEFPQLTAVVYFNDREIYDWPQGYGRPDWRVVRETISGQAPDGGM"
     misc_feature    complement(107962..108918)
                     /locus_tag="Smed_3669"
                     /note="Beta-mannanase [Carbohydrate transport and
                     metabolism]; Region: ManB; COG4124"
                     /db_xref="CDD:226609"
     sig_peptide     complement(108847..108918)
                     /locus_tag="Smed_3669"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 24"
     gene            complement(108915..109529)
                     /locus_tag="Smed_3670"
                     /db_xref="GeneID:5318067"
     CDS             complement(108915..109529)
                     /locus_tag="Smed_3670"
                     /note="PFAM: protein of unknown function DUF995;
                     KEGG: sme:SMb20461 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312416.1"
                     /db_xref="GI:150375820"
                     /db_xref="InterPro:IPR009337"
                     /db_xref="GeneID:5318067"
                     /translation="MKTKFTFVRNEGRSTRYALLGRRLALAILPVALFLFQSPASAEV
                     AVPEEARAMTGVELYMIFRGKSWKWESGAGRMESEGRVFRAWVQPGSGETWAEGRWSV
                     NDRGQLCLSAVWHSQNATVSDKTCFSHRTLDGTIYQKREPAGDWYVFKHAKRRADDEF
                     NRLVDEDLVDPKLPMVKERLTDQVNQTKDSVRRQVGMNAVGGVQ"
     sig_peptide     complement(109401..109529)
                     /locus_tag="Smed_3670"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.995 at
                     residue 43"
     misc_feature    complement(109020..109442)
                     /locus_tag="Smed_3670"
                     /note="Protein of unknown function (DUF995); Region:
                     DUF995; pfam06191"
                     /db_xref="CDD:218932"
     gene            complement(109534..111390)
                     /locus_tag="Smed_3671"
                     /db_xref="GeneID:5318068"
     CDS             complement(109534..111390)
                     /locus_tag="Smed_3671"
                     /note="KEGG: sme:SMb20460 putative cellulose synthase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative cellulose synthase"
                     /protein_id="YP_001312417.1"
                     /db_xref="GI:150375821"
                     /db_xref="GeneID:5318068"
                     /translation="MTRISAKKSTIMSAGGEPLLVPVFTGRRRLEYLLGAGLWVAALL
                     YFWAWWLEPSHHVDALGSAIVTAVLAWVTLLPAYFIAVFYRAAKPNGPLRIATGSRVA
                     MVVTKAPSEPFAIVAETLKAMLAQDVPHDTWLADEDPSDATLDWCRRHGVLVSTRKGL
                     ADYHRATWPRRTRCKEGNLAFFYDHYGYDGYDFVAQLDADHVPAPGYLFEVLRPFADP
                     EVGYVSAPSICDRNASQSWSARGRLYAEASMHGALQAGYNGGLAPLCIGSHYAVRTAA
                     LKEIGGLGPELAEDHSTTLMMNAAGWRGVHALDAIAHGDGPRTFADLVTQEFQWSRSL
                     VMLLLQYSPRLVGRLPLRLKFQFLFAQLWYPLFACFMALMFAMPIVALARGETFVAVT
                     YPEFLAYFAPLSAILVLLAYRWRATGAFRPCDAKVLSWECMLFLFARWPWALAGTLAA
                     LRDWLTGSFVDFRVTPKGSSEVDPLPLRVLAPYFALAIAAVLPVFLVEDAAKARGFYL
                     FAILNAAIYCLLLLVIVIRHSRENAVAAGSRFYRPAITAGLLAVIALPGIATAEHGKE
                     GLEALAWGSGHLRLFEDRYAVAGAGQGGTTLRKIVFSPRWISAPRGGKAERG"
     misc_feature    complement(109969..111243)
                     /locus_tag="Smed_3671"
                     /note="Glycosyltransferases, probably involved in cell
                     wall biogenesis [Cell envelope biogenesis, outer
                     membrane]; Region: COG1215"
                     /db_xref="CDD:224136"
     misc_feature    complement(110377..111093)
                     /locus_tag="Smed_3671"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cl11394"
                     /db_xref="CDD:245596"
     misc_feature    complement(order(110791..110793,110797..110799,
                     110986..110988,111064..111066,111070..111072))
                     /locus_tag="Smed_3671"
                     /note="active site"
                     /db_xref="CDD:132997"
     misc_feature    complement(<110155..>110532)
                     /locus_tag="Smed_3671"
                     /note="Cellulose synthase-like protein; Region: PLN02893"
                     /db_xref="CDD:215483"
     gene            complement(111387..112373)
                     /locus_tag="Smed_3672"
                     /db_xref="GeneID:5318069"
     CDS             complement(111387..112373)
                     /locus_tag="Smed_3672"
                     /note="TIGRFAM: UDP-glucose 4-epimerase;
                     PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase; polysaccharide
                     biosynthesis protein CapD; dTDP-4-dehydrorhamnose
                     reductase; Male sterility domain;
                     KEGG: sme:SMb20459 putative UDP-glucose 4-epimerase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="YP_001312418.1"
                     /db_xref="GI:150375822"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005886"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318069"
                     /translation="MGAPRILVTGGAGYIGSHTAKLLRLEGIEPIVYDNLTTGNRSAV
                     RWGPFVLGDILDGNHLVEVLEYHRPDAVIHFAASAYVGESVADPAKYYNNNVRGTLSL
                     LDACRRTGVDKVIFSSSCATYGVPAVLPIHETTPQDPINPYGKTKLMAEHMLADYAAA
                     FKLNYVALRYFNACGADPEGDLGEWHDPETHLIPRALMAAAGTILHLEIFGEDYDTPD
                     GTCVRDYIHVSDLASAHVLAYRHLAKGGENLAINVGTGRGFSIREVLRAIVEVTGRDV
                     PVVFRRRRFGDPPTLYADGGLACRTLGFLPRYSDLETIVRTAAPFFGLEARS"
     misc_feature    complement(111390..112364)
                     /locus_tag="Smed_3672"
                     /note="UDP-glucose 4-epimerase [Cell envelope biogenesis,
                     outer membrane]; Region: GalE; COG1087"
                     /db_xref="CDD:224012"
     misc_feature    complement(111420..112361)
                     /locus_tag="Smed_3672"
                     /note="UDP-glucose 4 epimerase, subgroup 1, extended (e)
                     SDRs; Region: UDP_G4E_1_SDR_e; cd05247"
                     /db_xref="CDD:187558"
     misc_feature    complement(order(111855..111857,111861..111866,
                     111933..111935,111945..111947,112017..112025,
                     112092..112094,112137..112139,112143..112151,
                     112212..112220,112257..112274,112329..112340,
                     112344..112346))
                     /locus_tag="Smed_3672"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187558"
     misc_feature    complement(order(111903..111911,111915..111920,
                     111927..111929,111939..111941,111948..111950,
                     112053..112055,112062..112067,112071..112076,
                     112083..112088,112095..112100,112107..112115,
                     112119..112121))
                     /locus_tag="Smed_3672"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187558"
     misc_feature    complement(order(111933..111935,111945..111947,
                     112017..112019,112089..112091))
                     /locus_tag="Smed_3672"
                     /note="active site"
                     /db_xref="CDD:187558"
     misc_feature    complement(order(111513..111515,111522..111524,
                     111591..111593,111699..111701,111705..111707,
                     111711..111713,111744..111755,111798..111806,
                     111858..111866,111945..111947,112011..112019))
                     /locus_tag="Smed_3672"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187558"
     gene            complement(112373..113419)
                     /locus_tag="Smed_3673"
                     /db_xref="GeneID:5318070"
     CDS             complement(112373..113419)
                     /locus_tag="Smed_3673"
                     /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase; Male sterility
                     domain;
                     KEGG: sme:SMb20458 putative dTDP-glucose 4,6-dehydratase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="YP_001312419.1"
                     /db_xref="GI:150375823"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318070"
                     /translation="MNYFRNDFKKTLLNVHEDRDALPRRSIQKSILVTGGAGFLGSHL
                     CELLLSAGHEVICLDNFSTGLRRNIAPLKRYDTFRVIAHDIVDPIDLEVDEIYNLACP
                     ASPPHYQADPIQTTKTCVIGSLNLLDLAARRGARIFQASTSEIYGDPQVHPQVESYWG
                     NVNSFGPRSCYDEGKRCAETLFFDYQKVHGVETKIVRIFNTYGPRMRPDDGRVVSNFI
                     VQALKGENITIYGDGSQTRSFCFVDDLIDGFVRLMGSPASLTGPVNLGNPTEFTIGEL
                     ADEVIRLTNSRSKIVRLPLPVDDPRQRRPDISLATKELGWRPKVNLAEGLAQTIRYFD
                     GVLSRSTRENAELV"
     misc_feature    complement(112418..113335)
                     /locus_tag="Smed_3673"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    complement(112421..113335)
                     /locus_tag="Smed_3673"
                     /note="UDP-glucuronate decarboxylase (UGD) and related
                     proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230"
                     /db_xref="CDD:187541"
     misc_feature    complement(order(112784..112786,112817..112828,
                     112895..112897,112907..112909,112994..113002,
                     113066..113068,113111..113125,113165..113173,
                     113228..113245,113300..113311,113315..113317))
                     /locus_tag="Smed_3673"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187541"
     misc_feature    complement(order(112865..112867,113024..113029,
                     113033..113038,113045..113050,113153..113158))
                     /locus_tag="Smed_3673"
                     /note="putative substrate binding site 2 [chemical
                     binding]; other site"
                     /db_xref="CDD:187541"
     misc_feature    complement(order(112511..112513,112523..112525,
                     112601..112603,112709..112711,112715..112717,
                     112730..112738,112769..112774,112781..112789,
                     112820..112822,112916..112918,113105..113107))
                     /locus_tag="Smed_3673"
                     /note="putative substrate binding site 1 [chemical
                     binding]; other site"
                     /db_xref="CDD:187541"
     misc_feature    complement(order(112895..112897,112907..112909,
                     112994..112996,113063..113065))
                     /locus_tag="Smed_3673"
                     /note="active site"
                     /db_xref="CDD:187541"
     gene            113778..114926
                     /locus_tag="Smed_3674"
                     /db_xref="GeneID:5318781"
     CDS             113778..114926
                     /locus_tag="Smed_3674"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type;
                     KEGG: sme:SMb20457 putative transcriptional regulator
                     transcription regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="YP_001312420.1"
                     /db_xref="GI:150375824"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="GeneID:5318781"
                     /translation="MTKDSGSGDDPVEVPAWPAHMERRRWPRDPSARKDRSAERSPAL
                     VPSRFSTRELPLEEQFKSWRAHMAPLVDVHLPDGVTEEHGFPAELVGWHLGDLLVVQQ
                     STPAHSYERSQAMLRSSPIDHWNVGLFRAGRSWTEADRRVTETGPGEFFFRSLGYPYR
                     GRMTDAAAILLFMPYELLADDVGKLEGANNSVLTGSLADLLANYLNGMEENLGNITVE
                     EVPRIVRTIRDMVVTCVAAVRPDTGGSQAKMGVMERAHRYIHLNLHSADLTPESICRE
                     LGVSRTRLYQLFEPSGGVLNYIRRRRLLQAHAELSDPTNYRPIAEIAETAGFDLAANF
                     TRAFSHEFGVSPREVRKAAAADRLVTPVAVPERDRGLTIGDWLRSIQG"
     misc_feature    114576..114827
                     /locus_tag="Smed_3674"
                     /note="helix_turn_helix, arabinose operon control protein;
                     Region: HTH_ARAC; smart00342"
                     /db_xref="CDD:197666"
     misc_feature    114705..114830
                     /locus_tag="Smed_3674"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     gene            complement(114969..115715)
                     /locus_tag="Smed_3675"
                     /db_xref="GeneID:5318782"
     CDS             complement(114969..115715)
                     /locus_tag="Smed_3675"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR; KR
                     domain protein;
                     KEGG: sme:SMb20456 putative dehydrogenasereductase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001312421.1"
                     /db_xref="GI:150375825"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR002424"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5318782"
                     /translation="MTTGALAGKAAFVTGGSRGIGAAIARKLAREGASVALTYVNSAD
                     QAQAVVSEIELAGGRAIAIRADNRDAESIERAVRHAAETLGRLDILVNSAGIWHSAPL
                     DETTVADFDEVMAVNFRAPFVAIRSASRHLGDGGRIITIGSNLAELVPWPGISLYSAS
                     KAALIGLTKGLARDLGPRGITVNIVHPGSTNTDMNPANGDHAEAQRERIATGGFGEPQ
                     DIAGFVAWLAGPDGKFVSGASLTIDGGANA"
     misc_feature    complement(114981..115700)
                     /locus_tag="Smed_3675"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Validated; Region: fabG; PRK05557"
                     /db_xref="CDD:235500"
     misc_feature    complement(114987..115685)
                     /locus_tag="Smed_3675"
                     /note="classical (c) SDRs; Region: SDR_c; cd05233"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(115137..115142,115146..115157,
                     115233..115235,115245..115247,115287..115295,
                     115368..115370,115431..115439,115515..115523,
                     115593..115601,115656..115667,115671..115673))
                     /locus_tag="Smed_3675"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(115233..115235,115245..115247,
                     115287..115289,115365..115367))
                     /locus_tag="Smed_3675"
                     /note="active site"
                     /db_xref="CDD:212491"
     gene            115816..116439
                     /locus_tag="Smed_3676"
                     /db_xref="GeneID:5318783"
     CDS             115816..116439
                     /locus_tag="Smed_3676"
                     /note="PFAM: regulatory protein TetR;
                     KEGG: sme:SMb20455 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_001312422.1"
                     /db_xref="GI:150375826"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="GeneID:5318783"
                     /translation="MPDKGRPRSFDRADALMRAMQVFWEKGFEGASLTALTAAMGINA
                     PSLYAAFGCKEALYLEAMELYAQTVGTEIWQPMETAPTAREAFSRFLAATAKAYSQPD
                     TPHGCLIALGGLHQSAIPKAVCDALSRHRTENVDKLRQRLEAAIAEGELPDSLDPEAV
                     ATFYATVQHGMSILARDGGSYQTLKNVADGAMAAWGMLTREDSVRRP"
     misc_feature    115816..116367
                     /locus_tag="Smed_3676"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    115870..115998
                     /locus_tag="Smed_3676"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:201228"
     gene            complement(116553..116972)
                     /locus_tag="Smed_3677"
                     /db_xref="GeneID:5318784"
     CDS             complement(116553..116972)
                     /locus_tag="Smed_3677"
                     /note="PFAM: protein of unknown function DUF1236;
                     KEGG: sme:SMb20454 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312423.1"
                     /db_xref="GI:150375827"
                     /db_xref="InterPro:IPR009642"
                     /db_xref="GeneID:5318784"
                     /translation="MKNLIIKGAIVLGVGLGCFAAPAAAQSTTKNSAVTGAAGGAAAG
                     AVVGGPVGAAVGGVAGAVAGAAIDPPPPKIIEYVETQPLPAEPVVVQQEIVVGKPLPE
                     TVVVTPIPDDSRYAYAVVNEKRVIVEPKSRTVVQVVQ"
     sig_peptide     complement(116895..116972)
                     /locus_tag="Smed_3677"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.994 at
                     residue 26"
     misc_feature    complement(116556..116744)
                     /locus_tag="Smed_3677"
                     /note="Protein of unknown function (DUF1236); Region:
                     DUF1236; pfam06823"
                     /db_xref="CDD:219192"
     gene            complement(117174..117527)
                     /locus_tag="Smed_3678"
                     /db_xref="GeneID:5318785"
     CDS             complement(117174..117527)
                     /locus_tag="Smed_3678"
                     /note="KEGG: sme:SMb20452 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312424.1"
                     /db_xref="GI:150375828"
                     /db_xref="InterPro:IPR002645"
                     /db_xref="GeneID:5318785"
                     /translation="MGTEYMEIKEDEYRVWSEGNDIYFDGTMRLPSTEAYAPIFALVT
                     SVLEAEPERMTVDLTGLQFLNSSGINLLAKLTIEARKRPNIQFTVRGSSEFPWQSKSL
                     PNLKKLHPGVDLRLG"
     misc_feature    complement(<117246..>117401)
                     /locus_tag="Smed_3678"
                     /note="Sulphate Transporter and Anti-Sigma factor
                     antagonist) domain of anti-anti-sigma factors, key
                     regulators of anti-sigma factors by phosphorylation;
                     Region: STAS_anti-anti-sigma_factors; cd07043"
                     /db_xref="CDD:132914"
     misc_feature    complement(order(117303..117308,117315..117323,
                     117327..117335,117339..117341))
                     /locus_tag="Smed_3678"
                     /note="anti sigma factor interaction site; other site"
                     /db_xref="CDD:132914"
     misc_feature    complement(117330..117332)
                     /locus_tag="Smed_3678"
                     /note="regulatory phosphorylation site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:132914"
     gene            complement(117527..118084)
                     /locus_tag="Smed_3679"
                     /db_xref="GeneID:5318786"
     CDS             complement(117527..118084)
                     /locus_tag="Smed_3679"
                     /note="KEGG: sme:SMb20451 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312425.1"
                     /db_xref="GI:150375829"
                     /db_xref="GeneID:5318786"
                     /translation="MTTLYGLEDLAVGPGENVTKLRLFDGPLDLGWKHCAMTSDFVAE
                     FAALRYKTSRVVYKEVRHNVGYLTNELIENAVKFRAGGEIVVEASIASNTFRTKVSNL
                     VDKGTADTFRHILSEITIGDPSDLLIQRIEANATGSGSGSGLGLLTLMSDYGAHFAWV
                     FGSGEEDGKIPLETYASIAIPDLSN"
     misc_feature    complement(117536..118084)
                     /locus_tag="Smed_3679"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG5381"
                     /db_xref="CDD:227672"
     gene            complement(118089..120449)
                     /locus_tag="Smed_3680"
                     /db_xref="GeneID:5318787"
     CDS             complement(118089..120449)
                     /locus_tag="Smed_3680"
                     /note="PFAM: histidine kinase HAMP region domain protein;
                     Cache domain protein; Stage II sporulation E family
                     protein;
                     SMART: protein phosphatase 2C domain protein;
                     KEGG: sme:SMb20450 putative regulatory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation E family protein"
                     /protein_id="YP_001312426.1"
                     /db_xref="GI:150375830"
                     /db_xref="InterPro:IPR001932"
                     /db_xref="InterPro:IPR003660"
                     /db_xref="InterPro:IPR004010"
                     /db_xref="InterPro:IPR010822"
                     /db_xref="GeneID:5318787"
                     /translation="MSVMGENTARLGLRSFRAKFVLVVGGAVLFDLLVTGGLALWNVQ
                     RLSRDAAAEVGRGLEEANQDYIRSYAETTAARVNLLLNQVHSDVGTLAGVLQEQIDRP
                     VRKSQIGEAMARGAPGTVAVAYDEKGGWAQNLPGPPSVVSVWGYLLDQNHFPLPDVQT
                     DIENSAVLDLVAPSLLANGQSKLQMYYIGPKERPIFRTAPYTDQAQTFDKLYPGHNAA
                     EFWSFFFPGLYESWEQWAREPESRPVNDDITQTAPYTDAITGKLIVSFFQPLWSRDRS
                     RVLGAAGTDITLDQLAEIVENVKVAETGFGFLTMSDGNVVAINPVGEKVIGLRASNAA
                     ASGGVTGLDRSLRRSIQPAIAQLPLEEDGLLKHILLEENGERVPYLVVLKHLQPTNLW
                     ASGPVSREAMLLGIAVPEREIYASLFAAQAGISKATNRILIYQVLALLVSLFFVIAAV
                     FAISKRITGGISALANAAKRIEAKDYSVRVDIPTRDEVGEAGAAFNRMAEEISFHTEN
                     LEQLVEDRTKEIEEANLQISALNQQLRSENLRLGAELAVARHIQMMVLPKAGELEEIA
                     ELEIAAYMRPADEVGGDYYDVLRDGNRLKIGIGDVTGHGLESGVLMLMVQSVARGLQE
                     VGEMEPAQFLNRVNRAIYKNLVRTSTNKHLSLAFLDYDGARLILSGQHEELIVIRDIE
                     KVERIDTLDLGLPIGLEPDISPFVATREISFGSGDMIVLHTDGVTEAESGSGELFGIE
                     RLCESARCRYGSSAEEVKSGIIEDLMTHIGTQKIHDDITLVVMRHR"
     misc_feature    complement(119499..119699)
                     /locus_tag="Smed_3680"
                     /note="Cache domain; Region: Cache_1; pfam02743"
                     /db_xref="CDD:217211"
     misc_feature    complement(118944..119081)
                     /locus_tag="Smed_3680"
                     /note="Histidine kinase, Adenylyl cyclase,
                     Methyl-accepting protein, and Phosphatase (HAMP) domain.
                     HAMP is a signaling domain which occurs in a wide variety
                     of signaling proteins, many of which are bacterial. The
                     HAMP domain consists of two alpha helices...; Region:
                     HAMP; cd06225"
                     /db_xref="CDD:100122"
     misc_feature    complement(order(118944..118949,118956..118961,
                     118965..118970,118977..118982,118986..118991,
                     119037..119039,119043..119048,119055..119060,
                     119064..119069,119076..119081))
                     /locus_tag="Smed_3680"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100122"
     misc_feature    complement(118092..>118955)
                     /locus_tag="Smed_3680"
                     /note="Serine phosphatase RsbU, regulator of sigma subunit
                     [Signal transduction mechanisms / Transcription]; Region:
                     RsbU; COG2208"
                     /db_xref="CDD:225118"
     misc_feature    complement(118092..118682)
                     /locus_tag="Smed_3680"
                     /note="Stage II sporulation protein E (SpoIIE); Region:
                     SpoIIE; pfam07228"
                     /db_xref="CDD:219343"
     gene            complement(120446..121624)
                     /locus_tag="Smed_3681"
                     /db_xref="GeneID:5318788"
     CDS             complement(120446..121624)
                     /locus_tag="Smed_3681"
                     /note="PFAM: UbiE/COQ5 methyltransferase;
                     Methyltransferase type 11; Methyltransferase type 12;
                     KEGG: sme:SMb20449 putative methyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="type 11 methyltransferase"
                     /protein_id="YP_001312427.1"
                     /db_xref="GI:150375831"
                     /db_xref="InterPro:IPR004033"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="GeneID:5318788"
                     /translation="MNTTALAVPFKAEFDPNSQEFALSGVVRPRSADEIAAIISMLKG
                     AIEEVRGVLYINVKRLVQMNNTAYHAFARVLLDSCRTRSDIRFVVVTSSVVGWTERMF
                     AHLNRIEPQVTVEVYDSKFYPGQSFVENTSFIPILRTQTKMTWRHERAILPRHGLRPG
                     MAMADICCGIGDFAMLARKEFQPARIVALDHSKASLAYARDVASGFGVTDIEYTYGDA
                     SEMLLEDNQFDFVTCRHSLQIFNQPDMLLKELFRICKPGGRVYITNEKNSHCLGEPRS
                     QSIQWTYNEVARLFSHFEMDVELGPKSKRYLVDAGFDDILVESFMVTNLDGDPQDFAD
                     IIAAWENVYAGEMAVKRGDPPEFIERFRQGFRDHIFAALHPKGYAGWPIWAASGRKPL
                     "
     misc_feature    complement(121280..121552)
                     /locus_tag="Smed_3681"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG5439"
                     /db_xref="CDD:227726"
     misc_feature    complement(120560..121321)
                     /locus_tag="Smed_3681"
                     /note="Methylase involved in ubiquinone/menaquinone
                     biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226"
                     /db_xref="CDD:225136"
     misc_feature    complement(120836..121132)
                     /locus_tag="Smed_3681"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(120923..120925,120971..120979,
                     121052..121057,121109..121129))
                     /locus_tag="Smed_3681"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(121621..122139)
                     /locus_tag="Smed_3682"
                     /db_xref="GeneID:5318789"
     CDS             complement(121621..122139)
                     /locus_tag="Smed_3682"
                     /note="KEGG: sme:SMb20448 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312428.1"
                     /db_xref="GI:150375832"
                     /db_xref="GeneID:5318789"
                     /translation="MHGAENHRTEAAYEPLLQFEMEMGAFLSDWNHCDQLSSFMARMI
                     SHNRTDPVRHSNFFSSALNELLEVSFRGGSPDGRIGCAVYRRGPTERVELTFPCPPGQ
                     RQFYGEAVAKTRDGDAHARYLDSIATDLAPSREAVLLDLSINFDADVRLGESDPPSIT
                     LVVDLPLEGVVR"
     gene            complement(122210..123904)
                     /locus_tag="Smed_3683"
                     /db_xref="GeneID:5318790"
     CDS             complement(122210..123904)
                     /locus_tag="Smed_3683"
                     /note="TIGRFAM: diguanylate cyclase;
                     PFAM: GGDEF domain containing protein; EAL domain protein;
                     KEGG: sme:SMb20447 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase/phosphodiesterase"
                     /protein_id="YP_001312429.1"
                     /db_xref="GI:150375833"
                     /db_xref="InterPro:IPR000160"
                     /db_xref="InterPro:IPR001633"
                     /db_xref="GeneID:5318790"
                     /translation="MPDGDTTLPGSPSVDSGFFADFDEVVSLYDENFQLIECTPRHRE
                     AYVVESLIETSLWHIYPELLAPGAKSAVEFVVATGLPRTVEIAHASAGPRRTLLIFRS
                     RSGVGVVEAESSAMYRETFRQSESDRALLLHQATHDVLTGLPNRRQFSDQLRGALPVP
                     NGAQVALMQIDLDDFKPINDTLGHGAGDAVLKMAADRIRSILRDREFAYRLAGDEFAV
                     IQWRSDQPSEAERLADALINAFKEPFMVEGINVFVGASVGIAVAPEDGNEVEQLMKAA
                     DIALYAAKKDGRGRSSTFTRSMLVVLEQREMLRRSLRTALQEGQFFLEYQPLVKPSSS
                     VAGFEALLRWRHPLVGTIPPNVFIPMAEADGLMSDIGRWLLERACRTAMDWPSHFTLA
                     VNLSPAEFLHEGLTDRVAQTLDLVGMRADRLELEITESVLLERTINNLDTLNTLNVLG
                     VQISLDDFGTYYSSLSYLKNFPFDTIKIDQYFIKDLERNEKGQTIVRSIIALAHGLGM
                     NVTAEGVETAGQAAWLQKEGCDRLQGYFLGAPMAADAIGDFLRKASATPATGLQRI"
     misc_feature    complement(123023..123559)
                     /locus_tag="Smed_3683"
                     /note="c-di-GMP synthetase (diguanylate cyclase, GGDEF
                     domain) [Signal    transduction mechanisms]; Region:
                     COG2199"
                     /db_xref="CDD:225109"
     misc_feature    complement(123035..123499)
                     /locus_tag="Smed_3683"
                     /note="Diguanylate-cyclase (DGC) or GGDEF domain; Region:
                     GGDEF; cd01949"
                     /db_xref="CDD:143635"
     misc_feature    complement(order(123263..123265,123392..123394))
                     /locus_tag="Smed_3683"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143635"
     misc_feature    complement(order(123260..123271,123275..123277,
                     123341..123343,123353..123355,123365..123370,
                     123377..123379))
                     /locus_tag="Smed_3683"
                     /note="active site"
                     /db_xref="CDD:143635"
     misc_feature    complement(order(123200..123202,123287..123289))
                     /locus_tag="Smed_3683"
                     /note="I-site; other site"
                     /db_xref="CDD:143635"
     misc_feature    complement(122270..122977)
                     /locus_tag="Smed_3683"
                     /note="EAL domain. This domain is found in diverse
                     bacterial signaling proteins. It is called EAL after its
                     conserved residues and is also known as domain of unknown
                     function 2 (DUF2).  The EAL domain has been shown to
                     stimulate degradation of a second...; Region: EAL;
                     cd01948"
                     /db_xref="CDD:238923"
     gene            complement(124140..125348)
                     /locus_tag="Smed_3684"
                     /db_xref="GeneID:5318802"
     CDS             complement(124140..125348)
                     /locus_tag="Smed_3684"
                     /EC_number="4.2.1.8"
                     /note="catalyzes the formation of
                     2-dehydro-3-deoxy-D-gluconate from mannonate"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="YP_001312430.1"
                     /db_xref="GI:150375834"
                     /db_xref="InterPro:IPR004628"
                     /db_xref="InterPro:IPR012307"
                     /db_xref="GeneID:5318802"
                     /translation="MRHTWRWFGPVDRVSVQDAAQAGAQGIVSALHHIPTGDVWPVDE
                     IGKRQEEVRAGGLEWEVVESVPVSECIKTQTGPWREHIANWQETLRRLSSAGIRTVCY
                     NFMPVLDWTRTDLRWTARHGAKAMRFDRIDFAAFDIHLLERPGAHEDYDAATREETER
                     RFREMPEERRLALSRNIGAGLPGSADGYSLPQLRDHLRSYDGISREKLQRHLVEFLTE
                     VTPVAERVGINICAHPDDPPWALLGLPRILSNAEDYAHMLREVDSPANGVTFCTGSLG
                     ALAANDLPAMVRRFASRIHFVHLRNVLREEERTPCSFYEDEHLEGNTDMVAVIAELLR
                     EEQLRRAAGRADHRIPMRPDHGQEILDDLSRGAQPGYPAIGRLKGLAELRGIERALSH
                     GTYGLAAAAT"
     misc_feature    complement(124155..125348)
                     /locus_tag="Smed_3684"
                     /note="mannonate dehydratase; Provisional; Region:
                     PRK03906"
                     /db_xref="CDD:235172"
     misc_feature    complement(124179..125348)
                     /locus_tag="Smed_3684"
                     /note="mannonate dehydratase; Region: uxuA; TIGR00695"
                     /db_xref="CDD:129778"
     gene            complement(125358..126401)
                     /locus_tag="Smed_3685"
                     /db_xref="GeneID:5318803"
     CDS             complement(125358..126401)
                     /locus_tag="Smed_3685"
                     /note="PFAM: Alcohol dehydrogenase zinc-binding domain
                     protein; Alcohol dehydrogenase GroES domain protein;
                     KEGG: sme:SMb20445 putative alcohol dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="YP_001312431.1"
                     /db_xref="GI:150375835"
                     /db_xref="InterPro:IPR002328"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="GeneID:5318803"
                     /translation="MHTRLARLYGQRDLRVELAEVPAPGHGEVLLKMAAGGICGSDLH
                     YYQDGGFGPVRVREPIIPGHEASGRVGAFGGDVSGLDVGDLVAVNPSQPCGACRFCGD
                     GLAVHCLNMRFLGSAMRLPHTQGMFRDWLVVPARQCHPAGTLVGAGEAACAEPLAVCL
                     HALAQAGDVRRKKILVTGAGPIGALVVAAVRHGGADEVVVTDLADAALDRAMAMGATR
                     TINIGRDPAGLAPYETDKGQFHLAFECSAAEPALRSAVAAVRPRGMIVQVGVTGDVKL
                     PLHALVGKELRLVGSQRFDQEFALAVALIADRRIDVRPIISHQFPVEEAVRAFEQAGD
                     RSAACKVQLTFLS"
     misc_feature    complement(125367..126386)
                     /locus_tag="Smed_3685"
                     /note="L-idonate 5-dehydrogenase; Region: idonate-5-DH;
                     cd08232"
                     /db_xref="CDD:176194"
     misc_feature    complement(125367..126374)
                     /locus_tag="Smed_3685"
                     /note="L-idonate 5-dehydrogenase; Provisional; Region:
                     PRK09880"
                     /db_xref="CDD:182130"
     misc_feature    complement(order(125523..125531,125595..125600,
                     125658..125660,125664..125669,125736..125738,
                     125781..125783,125793..125798,125853..125870,
                     125928..125930,125940..125942,126270..126272,
                     126279..126287))
                     /locus_tag="Smed_3685"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176194"
     misc_feature    complement(order(125940..125942,126210..126212,
                     126279..126281,126285..126287))
                     /locus_tag="Smed_3685"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176194"
     gene            complement(126416..127822)
                     /locus_tag="Smed_3686"
                     /db_xref="GeneID:5318804"
     CDS             complement(126416..127822)
                     /locus_tag="Smed_3686"
                     /note="TIGRFAM: TRAP dicarboxylate transporter, DctM
                     subunit;
                     PFAM: TRAP C4-dicarboxylate transport system permease DctM
                     subunit;
                     KEGG: sme:SMb20444 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctM"
                     /protein_id="YP_001312432.1"
                     /db_xref="GI:150375836"
                     /db_xref="InterPro:IPR004681"
                     /db_xref="InterPro:IPR010656"
                     /db_xref="GeneID:5318804"
                     /translation="MLLLVVSFLFLMLVGVPVAISMASASVLYLVFYNVAPDIIAAQR
                     MIAGVESFPLLAVPFFILAGNLMNSAGVTGRIYSFAVALVGWMKGGLAQVNIVGSVIF
                     SGMSGTALADAAGIGTIEIKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMM
                     ANVSIGALFMAGVVPGVVMTVLMMLTVAIFAYKRGWGSDTPFEMKRLLSASLEVVVVL
                     AVPLLVYALMSAGLSMNLAVGIALVVLLALDWYFDFSAVMALMTPIILIGGMTMGWFT
                     PTEAAVAAVIWSLFLGLVRYRTMTMSTLARATFDTIETTASVLFIVTAASIFAWLLTV
                     SQAAQMLSGAILTITDNKWVFLILVNLLMLFVGCFLDTIAAITILVPILLPLTAQFGI
                     DPVHFGLIMTLNLMIGLLHPPLGMVLFVLSRVAKLSVERTTMAILPWLVPLFIALILI
                     TFVPAVVLWLPQTVGLIR"
     sig_peptide     complement(127745..127822)
                     /locus_tag="Smed_3686"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.998) with cleavage site probability 0.648 at
                     residue 26"
     misc_feature    complement(126455..127780)
                     /locus_tag="Smed_3686"
                     /note="DctM-like transporters; Region: DctM; pfam06808"
                     /db_xref="CDD:219185"
     misc_feature    complement(126428..127690)
                     /locus_tag="Smed_3686"
                     /note="TRAP-type C4-dicarboxylate transport system, large
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctQ; COG1593"
                     /db_xref="CDD:224509"
     gene            complement(127828..128415)
                     /locus_tag="Smed_3687"
                     /db_xref="GeneID:5318805"
     CDS             complement(127828..128415)
                     /locus_tag="Smed_3687"
                     /note="PFAM: Tripartite ATP-independent periplasmic
                     transporter DctQ component;
                     KEGG: sme:SMb20443 putative permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite ATP-independent periplasmic
                     transporter DctQ"
                     /protein_id="YP_001312433.1"
                     /db_xref="GI:150375837"
                     /db_xref="InterPro:IPR007387"
                     /db_xref="GeneID:5318805"
                     /translation="MPDDAMSQEVHLQTTPEEIAHAFEEAPPSADLSNYSFEDWVTLA
                     VFWLMTGCVFLQFFTRYVLNDSYAWTEEIATNCLIGVVFLGSAMCVRVSRHIQVDVLY
                     HYLPATVARGLAIFVDLVRIVFFGYACWLMWRYVAIVAHERMITVNLPRNIVFYGVLA
                     GFVLMLIRSIQVFVANQRRGYSVLEKPEEFHKVED"
     misc_feature    complement(127843..128349)
                     /locus_tag="Smed_3687"
                     /note="TRAP-type C4-dicarboxylate transport system, small
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctM; COG3090"
                     /db_xref="CDD:225632"
     gene            complement(128469..129443)
                     /locus_tag="Smed_3688"
                     /db_xref="GeneID:5318806"
     CDS             complement(128469..129443)
                     /locus_tag="Smed_3688"
                     /note="TIGRFAM: TRAP dicarboxylate transporter, DctP
                     subunit;
                     PFAM: TRAP dicarboxylate transporter- DctP subunit;
                     KEGG: sme:SMb20442 putative periplasmic solute-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctP"
                     /protein_id="YP_001312434.1"
                     /db_xref="GI:150375838"
                     /db_xref="InterPro:IPR004682"
                     /db_xref="GeneID:5318806"
                     /translation="MTIRLLTLIGATATILASALSAHAQTALKWAHVYETSEPFHTES
                     VWAAEEIAKRTEGRYKIDVFPASQLGKEADINQGLKLGTVDIIISGSSFAARDHAPIG
                     VTYFPYIFRDPAHMIAYTKSDVFKRLAAGYEEASGNHITAVTYYGTRHTTSNRPITKC
                     ADMQGLKMRVPDVPAYLAMPRACGANTTPIAFAEVYLALQNGTVEAQENPLTTIEAKK
                     FFEVQKHIVLTGHIVDHLNTVVSKNLWSQLSDADKQIFTEVMQEAAERATKIIEEREK
                     ELVATFKERGIEVTEVDRADFEKTVNEKVALEDFGYVKEDWEAIRAVK"
     sig_peptide     complement(129369..129443)
                     /locus_tag="Smed_3688"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.993 at
                     residue 25"
     misc_feature    complement(128472..129362)
                     /locus_tag="Smed_3688"
                     /note="TRAP-type C4-dicarboxylate transport system,
                     periplasmic component [Carbohydrate transport and
                     metabolism]; Region: DctP; COG1638"
                     /db_xref="CDD:224553"
     misc_feature    complement(128526..129353)
                     /locus_tag="Smed_3688"
                     /note="Bacterial extracellular solute-binding protein,
                     family 7; Region: SBP_bac_7; pfam03480"
                     /db_xref="CDD:202660"
     gene            complement(129479..130222)
                     /locus_tag="Smed_3689"
                     /db_xref="GeneID:5318807"
     CDS             complement(129479..130222)
                     /locus_tag="Smed_3689"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20441 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312435.1"
                     /db_xref="GI:150375839"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318807"
                     /translation="MMFSAVESRRLYRQVADQMRALIERGELAHGSRLPAERELAQMF
                     GVSRPTIREALIVLEVEGFIDIRMGSGIYVTARPAPAADGPPEDFEGPFELLRARAVV
                     ECAIAEEAARLARPEHIAVLDDNLARMAAALEDRRLALAIDREFHVVVSSIIANATLN
                     RFVGSIHDMRMTPYFEKLASYFENTDTWRAAMEEHRVIRNAIAAGDPGAARAAMRAHL
                     DQSQIRLSASFEEEAADSTIPAAWRRVGR"
     misc_feature    complement(129518..130222)
                     /locus_tag="Smed_3689"
                     /note="Transcriptional regulators [Transcription]; Region:
                     FadR; COG2186"
                     /db_xref="CDD:225097"
     misc_feature    complement(129998..130192)
                     /locus_tag="Smed_3689"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(130007..130018,130022..130027,
                     130055..130057,130064..130069,130073..130087,
                     130109..130114,130118..130120,130187..130189))
                     /locus_tag="Smed_3689"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     gene            complement(130528..131802)
                     /locus_tag="Smed_3690"
                     /db_xref="GeneID:5318808"
     CDS             complement(130528..131802)
                     /locus_tag="Smed_3690"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: sme:SMb20436 putative nitrate transporter protein"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001312436.1"
                     /db_xref="GI:150375840"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5318808"
                     /translation="MSALHQTQSTLKGASARALWASTGAFTICFAIWTIFSIIGVRIK
                     EDLGLSEAEFGLLIGMPILTGSLVRIVLGIWTTRYGGRLVYTLTMLAAALATFLLGYA
                     TTYPQMLLAGLGVGLAGGSFAVGVAYVSPFFPPEKQGTALGIFGAGNVGAAVTKFLAP
                     FVLVAFGWQAVAEIWAAVLAVTAIIFWFSTEDDPQFRARRQGAVARKSLLSEFEPLKN
                     VQVWRFSLYYFFAFGGFVALALWLPRYLVGVYGFNIETAGMIAAAYSIPGSIFRAYGG
                     ALSDKLGARKVMYAMFAVSAVATAILSVPAGSASGAMPIMVTPLVFVFVTFVLGFVMS
                     LGKAAVYKHIPVYYPTHVGAVGGVVGMVGGLGGFVLPIAFGYLKDVTGLWSSCFMLLF
                     VIVAVSMIWMKVSIRQIKREADRGVPSGALAR"
     misc_feature    complement(130567..131793)
                     /locus_tag="Smed_3690"
                     /note="Nitrate/nitrite transporter [Inorganic ion
                     transport and metabolism]; Region: NarK; COG2223"
                     /db_xref="CDD:225133"
     misc_feature    complement(<130855..131748)
                     /locus_tag="Smed_3690"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(order(130987..130989,130999..131001,
                     131008..131010,131020..131022,131032..131034,
                     131074..131076,131083..131088,131095..131100,
                     131107..131109,131347..131349,131362..131367,
                     131374..131379,131413..131415,131422..131427,
                     131434..131439,131446..131451,131584..131589,
                     131593..131598,131608..131610,131617..131622,
                     131629..131631,131680..131685,131689..131697,
                     131704..131706))
                     /locus_tag="Smed_3690"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            132330..133301
                     /locus_tag="Smed_3691"
                     /db_xref="GeneID:5318809"
     CDS             132330..133301
                     /locus_tag="Smed_3691"
                     /note="PFAM: transposase IS111A/IS1328/IS1533; transposase
                     IS116/IS110/IS902 family protein;
                     KEGG: hne:HNE_2108 ISHne4, transposase"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS116/IS110/IS902 family protein"
                     /protein_id="YP_001312437.1"
                     /db_xref="GI:150375841"
                     /db_xref="InterPro:IPR002525"
                     /db_xref="InterPro:IPR003346"
                     /db_xref="GeneID:5318809"
                     /translation="MIHPDVIGCDIAKAHLDFFDSGLERHFRIDNTPAAISAWLDGLD
                     GRGVHIVFEATGRYDRQLRIALETRELPYSRVNPARARDFAKAIGLLAKTDAIDARLL
                     ARMGQSLPLSTQAPDDPARHVLARLHTRRDQLVAMRQQERTRLHETEGIERDSAESHM
                     AWLDAEVARIEMACRDVLKAEKTLQEQEARLRSIPGIGPVAALTLIAHMPELGNRSAK
                     AIAALAGLAPFNVDSGTSRGKRHIRGGRKRIRDALYMAALTASRMPRAFKSHADQMKE
                     AGKPFKVRHHCACPQIARHRKRHHQGQNNLPTNHLTNTVASQTKSLG"
     misc_feature    132345..132761
                     /locus_tag="Smed_3691"
                     /note="Transposase; Region: DEDD_Tnp_IS110; pfam01548"
                     /db_xref="CDD:216564"
     misc_feature    132474..>132950
                     /locus_tag="Smed_3691"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG3547"
                     /db_xref="CDD:226077"
     misc_feature    132894..133139
                     /locus_tag="Smed_3691"
                     /note="Transposase IS116/IS110/IS902 family; Region:
                     Transposase_20; pfam02371"
                     /db_xref="CDD:217002"
     gene            complement(133392..134396)
                     /locus_tag="Smed_3692"
                     /db_xref="GeneID:5318810"
     CDS             complement(133392..134396)
                     /locus_tag="Smed_3692"
                     /note="TIGRFAM: Ectoine utilization protein EutE;
                     PFAM: Succinylglutamate desuccinylase/aspartoacylase;
                     KEGG: sme:SMb20435 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ectoine utilization protein EutE"
                     /protein_id="YP_001312438.1"
                     /db_xref="GI:150375842"
                     /db_xref="InterPro:IPR007036"
                     /db_xref="InterPro:IPR014336"
                     /db_xref="GeneID:5318810"
                     /translation="MREHHLRPSPISATVDFEADGIQHGFLRLPYSRDDSAWGSVMIP
                     ISVVKNGKGPTALLTGGNHGDEYEGPIALFDLARKLDAADVEGRVIIVPAMNYPAFQA
                     QTRTSPIDRGNMNRSFPGKPDGTVTQKIADYFQRVLLPLADIVLDFHSGGKTLDFLPF
                     CAAHVLPDKAQEERAFEFVRAFGAPYSMKMLEIDTVGMYDTAAEEMGKIFVTTELGGG
                     GSATARTASIAKRGVVNVLKHAGILEGEVETASTRWLDMPSDDCFAFAEDEGLVEFLV
                     DLGEAVARDAVIARVYPIGRTGVEPVEVRARMNGLLVARHNPGLIKPGDCCAVLAVEV
                     "
     misc_feature    complement(133404..134378)
                     /locus_tag="Smed_3692"
                     /note="ectoine utilization protein EutE; Region:
                     ectoine_eutE; TIGR02994"
                     /db_xref="CDD:132039"
     misc_feature    complement(133401..134339)
                     /locus_tag="Smed_3692"
                     /note="Peptidase M14 Succinylglutamate desuccinylase
                     (ASTE)/aspartoacylase (ASPA)-like; uncharacterized
                     subgroup; Region: M14_ASTE_ASPA_like_2; cd06252"
                     /db_xref="CDD:199872"
     misc_feature    complement(order(133755..133757,133797..133799,
                     133809..133811,133911..133913,133950..133952,
                     134049..134054,134082..134084,134199..134201,
                     134208..134210))
                     /locus_tag="Smed_3692"
                     /note="putative active site [active]"
                     /db_xref="CDD:199872"
     misc_feature    complement(order(133950..133952,134199..134201,
                     134208..134210))
                     /locus_tag="Smed_3692"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:199872"
     gene            complement(134401..135582)
                     /locus_tag="Smed_3693"
                     /db_xref="GeneID:5318302"
     CDS             complement(134401..135582)
                     /locus_tag="Smed_3693"
                     /note="TIGRFAM: Ectoine utilization protein EutD;
                     PFAM: creatinase; peptidase M24;
                     KEGG: sme:SMb20434 putative hydrolasepeptidase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ectoine utilization protein EutD"
                     /protein_id="YP_001312439.1"
                     /db_xref="GI:150375843"
                     /db_xref="InterPro:IPR000587"
                     /db_xref="InterPro:IPR000994"
                     /db_xref="InterPro:IPR001202"
                     /db_xref="InterPro:IPR014335"
                     /db_xref="GeneID:5318302"
                     /translation="MTQPNLKFSLEEYEARLAKTRKAMEAKGVDLLIVSDPSNMAWLT
                     GYDGWSFYVHQAVIVPPSGEPIWFGRGQDANGAKFTAYLKHENIIGYPDHYVQSTERH
                     PMDYLSGILADRGFGSLRIGVEMDNYWFSAAAFASLQKRLPNARFVDTTALVNWQRAV
                     KSETEIKYMRNAARIVEAMHQRIFDKIEVGMRKCDLVAEIYDAGTRGVDGIGGDYPAI
                     VPLLPSGVEASAPHLTWDDRPMKRGEGTFFEIAGCYNRYHLPLSRTVFLGKPTQAFLD
                     AEKATLEGMEAGLAVAKPGNTCEDIANAFFSVLKKYGIVKDNRTGYPIGLSYPPDWGE
                     RTMSLRSGDRTELKPGMTFHFMTGLWLEDMGFETTESILITESGVECLASVPRKLMVK
                     D"
     misc_feature    complement(134404..135576)
                     /locus_tag="Smed_3693"
                     /note="ectoine utilization protein EutD; Region:
                     ectoine_eutD; TIGR02993"
                     /db_xref="CDD:211774"
     misc_feature    complement(135103..135537)
                     /locus_tag="Smed_3693"
                     /note="Creatinase/Prolidase N-terminal domain; Region:
                     Creatinase_N; pfam01321"
                     /db_xref="CDD:216431"
     misc_feature    complement(134449..135087)
                     /locus_tag="Smed_3693"
                     /note="A family including aminopeptidase P, aminopeptidase
                     M, and prolidase. Also known as metallopeptidase family
                     M24. This family of enzymes is able to cleave amido-,
                     imido- and amidino-containing bonds. Members exibit
                     relatively narrow substrate specificity...; Region:
                     APP_MetAP; cd01066"
                     /db_xref="CDD:238514"
     misc_feature    complement(order(134476..134478,134515..134517,
                     134617..134619,134803..134805,134836..134838,
                     134887..134889))
                     /locus_tag="Smed_3693"
                     /note="active site"
                     /db_xref="CDD:238514"
     gene            complement(135628..136617)
                     /locus_tag="Smed_3694"
                     /db_xref="GeneID:5318303"
     CDS             complement(135628..136617)
                     /locus_tag="Smed_3694"
                     /EC_number="4.3.1.12"
                     /note="putative cyclodeaminase"
                     /codon_start=1
                     /transl_table=11
                     /product="ectoine utilization protein EutC"
                     /protein_id="YP_001312440.1"
                     /db_xref="GI:150375844"
                     /db_xref="InterPro:IPR003462"
                     /db_xref="InterPro:IPR014334"
                     /db_xref="GeneID:5318303"
                     /translation="MTRMKILTERQLRSIVPLDREAVACVEEAFHALATKAVAMPPIL
                     RLDIPEHRGEVDVKTAYVPGLDGFAIKISPGFFDNPKLGLPSTNGMMVLLSSKTGLVQ
                     ALLLDNGYLTDVRTAAAGAVAARHLSREDASIATVFGAGMQAGLQLEALALVRPIREA
                     RIWARDAGKAEAAAREMTDKLGFAVSAVVDPVAAVSGADIIVTTTPSETPVLKAEWLQ
                     PGQHVTVMGSDTEHKNELDPHAFARATYVADSLRQTRRLGELHHAIAARLVPAEAEFA
                     ELGQVIAGMKPGRTRAEEITIADLTGTGIQDTAIATLAFARANTADASTTFDS"
     misc_feature    complement(135631..136617)
                     /locus_tag="Smed_3694"
                     /note="ectoine utilization protein EutC; Validated;
                     Region: PRK08291"
                     /db_xref="CDD:236221"
     misc_feature    complement(135667..136608)
                     /locus_tag="Smed_3694"
                     /note="ornithine cyclodeaminase; Validated; Region:
                     PRK06823; cl17400"
                     /db_xref="CDD:247954"
     gene            complement(136614..137618)
                     /gene="eutB"
                     /locus_tag="Smed_3695"
                     /db_xref="GeneID:5318304"
     CDS             complement(136614..137618)
                     /gene="eutB"
                     /locus_tag="Smed_3695"
                     /EC_number="4.3.1.19"
                     /note="catalyzes the formation of 2-oxobutanoate from
                     L-threonine; involved in ectoine utilization"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine dehydratase"
                     /protein_id="YP_001312441.1"
                     /db_xref="GI:150375845"
                     /db_xref="InterPro:IPR000634"
                     /db_xref="InterPro:IPR001926"
                     /db_xref="InterPro:IPR014333"
                     /db_xref="GeneID:5318304"
                     /translation="MSVSLPVTIDDIEAAARRISGRVRTTPLVDSASLSERIGVPVGL
                     KLEHHQTTGSFKLRGATNAVLSLSPGDRALGVIAASTGNHGRALAHAAKAEGSVATIC
                     MSHLVPLNKVSEIRRLGAHVRIIGNSQDEAQVEVERLVAENGLVMVPPFDNAAVVAGQ
                     GTLGLEIVTQMPDVSTVLVPVSGGGLAAGVAAAVKARKPATRVIGLTMERGAAMQASI
                     AAGGPVLVDEYPSLADSLGGGIGLDNRVTFRMCRELLDEIILLTEDEIAAGMRHAYAE
                     EREIVEGAGAVGIAALLAGKIRDIDGPIAIILSGRNVDMDLHLRVMNGEADPFRGEAA
                     "
     misc_feature    complement(136644..137618)
                     /gene="eutB"
                     /locus_tag="Smed_3695"
                     /note="Threonine dehydratase [Amino acid transport and
                     metabolism]; Region: IlvA; COG1171"
                     /db_xref="CDD:224092"
     misc_feature    complement(136677..137594)
                     /gene="eutB"
                     /locus_tag="Smed_3695"
                     /note="Threonine dehydratase: The first step in amino acid
                     degradation is the removal of nitrogen. Although the
                     nitrogen atoms of most amino acids are transferred to
                     alpha-ketoglutarate before removal, the alpha-amino group
                     of threonine can be directly...; Region: Thr-dehyd;
                     cd01562"
                     /db_xref="CDD:107205"
     misc_feature    complement(order(136677..136688,136779..136787,
                     136797..136799,136806..136811,136818..136820,
                     137031..137036,137472..137477,137568..137573,
                     137580..137582,137589..137594))
                     /gene="eutB"
                     /locus_tag="Smed_3695"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107205"
     misc_feature    complement(order(136692..136694,137061..137075,
                     137370..137372,137451..137453))
                     /gene="eutB"
                     /locus_tag="Smed_3695"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:107205"
     misc_feature    complement(137451..137453)
                     /gene="eutB"
                     /locus_tag="Smed_3695"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:107205"
     gene            complement(137615..138400)
                     /locus_tag="Smed_3696"
                     /db_xref="GeneID:5318305"
     CDS             complement(137615..138400)
                     /locus_tag="Smed_3696"
                     /note="TIGRFAM: Ectoine utilization protein EutA;
                     PFAM: Asp/Glu racemase;
                     KEGG: sme:SMb20431 hypothetical arylmalonate decarboxylase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ectoine utilization protein EutA"
                     /protein_id="YP_001312442.1"
                     /db_xref="GI:150375846"
                     /db_xref="InterPro:IPR001920"
                     /db_xref="InterPro:IPR014332"
                     /db_xref="GeneID:5318305"
                     /translation="MKSPVALSLASRSPRLDARPVNRRIGLVILATDHTTEVDFQRMV
                     ASDRIGVYVTRIPYANPVTPENLRAMQPSLTEAAALILPDETLDVVMYSCTSASVVIG
                     DEEVAAAITAAKPGATVVTPTDASVRGLRALGAKNISVLTPYTIETSRPMAGYFAERG
                     FAIDRFTCLGLTDDREMARIRPEEIVAFAKEAAAAESDALFISCTAVRAAVKIAEIEQ
                     AIGKPVVSSNYATAWACLRLCGDQEARPHLGRLMELPLEGERL"
     misc_feature    complement(137639..138355)
                     /locus_tag="Smed_3696"
                     /note="Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race;
                     cl00518"
                     /db_xref="CDD:241919"
     gene            complement(138400..139062)
                     /locus_tag="Smed_3697"
                     /db_xref="GeneID:5318306"
     CDS             complement(138400..139062)
                     /locus_tag="Smed_3697"
                     /note="TIGRFAM: polar amino acid ABC transporter, inner
                     membrane subunit; Ectoine/hydroxyectoine ABC transporter
                     permease protein EhuD;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb20430 putative amino acid ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ectoine/hydroxyectoine ABC transporter permease
                     EhuD"
                     /protein_id="YP_001312443.1"
                     /db_xref="GI:150375847"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR010065"
                     /db_xref="InterPro:IPR014341"
                     /db_xref="GeneID:5318306"
                     /translation="MEWDWEFVRQIMPTLIEGLKITILATALGAVVAAVIGLVFAILR
                     MTAPKPIARATSFIVEFIRGTPLLVQLYFIFYVLPDVGIRLPALVAGVIGLGIHYGTY
                     AAEVYRAGIENVPRGQWEAAKATNLTARQTWIHVILPQAIPPMIPALANYLIAMFKET
                     PLLSAITVLELMNQAKSIANSNYRYIEPMTLVGVFFLIMSLISVVFLRWLEERYSRVE
                     QR"
     misc_feature    complement(138448..138921)
                     /locus_tag="Smed_3697"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(138448..138453,138460..138465,
                     138472..138477,138481..138486,138493..138498,
                     138526..138531,138568..138573,138580..138591,
                     138610..138612,138619..138624,138664..138666,
                     138715..138717,138724..138729,138739..138741,
                     138745..138750,138757..138759,138763..138765,
                     138769..138774,138847..138849,138856..138885,
                     138889..138900))
                     /locus_tag="Smed_3697"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(138574..138591,138847..138852,
                     138853..138882))
                     /locus_tag="Smed_3697"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(138496..138498,138526..138528,
                     138535..138537,138571..138573,138787..138789,
                     138847..138849))
                     /locus_tag="Smed_3697"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(138643..138645,138655..138660,
                     138676..138714))
                     /locus_tag="Smed_3697"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(139065..139784)
                     /locus_tag="Smed_3698"
                     /db_xref="GeneID:5318307"
     CDS             complement(139065..139784)
                     /locus_tag="Smed_3698"
                     /note="TIGRFAM: polar amino acid ABC transporter, inner
                     membrane subunit; Ectoine/hydroxyectoine ABC transporter
                     permease protein EhuC;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb20429 putative amino acid ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ectoine/hydroxyectoine ABC transporter permease
                     EhuC"
                     /protein_id="YP_001312444.1"
                     /db_xref="GI:150375848"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR010065"
                     /db_xref="InterPro:IPR014342"
                     /db_xref="GeneID:5318307"
                     /translation="MGRRCGRRQPGPNSDWNNETMIDWSGYIGLILQGAWVTVQLTLM
                     GSALAVVVAFAAGLGRLSRFMAVRALATTYIEFFRGTSIFVQLFWAYFVLPFAGITLT
                     PLQAGVLALGLNVGAYGAEVVRGAVKAIGREQREACIALNLTRFQAMRHIILPQALPL
                     MLPTFGNNAIELLKGTAVVSLISLTDMTFQAQVVRAQTGSTLIPFATILLLYFAMAWL
                     ISMGMRWLERRVSRGLDGVRV"
     misc_feature    complement(139086..139709)
                     /locus_tag="Smed_3698"
                     /note="ABC-type arginine transport system, permease
                     component [Amino acid transport and metabolism]; Region:
                     ArtQ; COG4215"
                     /db_xref="CDD:226670"
     misc_feature    complement(139134..139586)
                     /locus_tag="Smed_3698"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(139134..139139,139146..139151,
                     139158..139163,139167..139172,139179..139184,
                     139212..139217,139242..139247,139254..139265,
                     139284..139286,139293..139298,139338..139340,
                     139389..139391,139398..139403,139413..139415,
                     139419..139424,139431..139433,139437..139439,
                     139443..139448,139512..139514,139518..139523,
                     139530..139559,139563..139574))
                     /locus_tag="Smed_3698"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(139248..139265,139512..139556))
                     /locus_tag="Smed_3698"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(139182..139184,139212..139214,
                     139221..139223,139245..139247,139461..139463,
                     139512..139514))
                     /locus_tag="Smed_3698"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(139317..139319,139329..139334,
                     139350..139388))
                     /locus_tag="Smed_3698"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(139828..140679)
                     /locus_tag="Smed_3699"
                     /db_xref="GeneID:5318308"
     CDS             complement(139828..140679)
                     /locus_tag="Smed_3699"
                     /note="TIGRFAM: Ectoine/hydroxyEctoine ABC transporter
                     solute-binding protein;
                     PFAM: extracellular solute-binding protein family 3;
                     KEGG: sme:SMb20428 putative ABC transporter amino
                     acid-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ectoine/hydroxyectoine ABC transporter
                     solute-binding protein"
                     /protein_id="YP_001312445.1"
                     /db_xref="GI:150375849"
                     /db_xref="InterPro:IPR001638"
                     /db_xref="InterPro:IPR014337"
                     /db_xref="GeneID:5318308"
                     /translation="MKLRDWMAMAAGATALMAVAAATPATADENKLDELKEQGFARIA
                     IANEPPFTAVGADGKVSGAAPDVAREVFKRLGVADVVASISEYGAMIPGLQAGRHDAI
                     TAGLFMKPERCAAVAYSEPILCDAEAFALKKGNPLGLKSYKDIADNPDAKIGAPGGGT
                     EEKLALEAGVPRDRVIVVPDGQSGMKMLQDGRIDVYSLPVLSINDLVSKANDPNIEVV
                     APVEGAPVYCDGAAFKKGDEALRDAFDVELAKLKESGEFAKIIEPYGFSAKAAMSTTR
                     EKLCAAK"
     sig_peptide     complement(140596..140679)
                     /locus_tag="Smed_3699"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.969 at
                     residue 28"
     misc_feature    complement(139840..140598)
                     /locus_tag="Smed_3699"
                     /note="ectoine/hydroxyectoine ABC transporter
                     solute-binding protein; Region: ectoine_ehuB; TIGR02995"
                     /db_xref="CDD:132040"
     misc_feature    complement(139885..140556)
                     /locus_tag="Smed_3699"
                     /note="Bacterial periplasmic transport systems use
                     membrane-bound complexes and substrate-bound,
                     membrane-associated, periplasmic binding proteins (PBPs)
                     to transport a wide variety of  substrates, such as, amino
                     acids, peptides, sugars, vitamins and inorganic...;
                     Region: PBPb; cd00134"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(140083..140085,140200..140202,
                     140344..140346,140419..140421))
                     /locus_tag="Smed_3699"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(140104..140106,140122..140124,
                     140134..140136))
                     /locus_tag="Smed_3699"
                     /note="membrane-bound complex binding site; other site"
                     /db_xref="CDD:238078"
     misc_feature    complement(139990..140007)
                     /locus_tag="Smed_3699"
                     /note="hinge residues; other site"
                     /db_xref="CDD:238078"
     gene            complement(140738..141523)
                     /locus_tag="Smed_3700"
                     /db_xref="GeneID:5318309"
     CDS             complement(140738..141523)
                     /locus_tag="Smed_3700"
                     /note="TIGRFAM: Ectoine/hydroxyectoine ABC transporter
                     ATP-binding protein;
                     PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20427 putative amino acid ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ectoine/hydroxyectoine ABC transporter
                     ATP-binding protein"
                     /protein_id="YP_001312446.1"
                     /db_xref="GI:150375850"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR014343"
                     /db_xref="GeneID:5318309"
                     /translation="MSQPIIRIDNIVKRYGPLTVLDGLSMEVMPGEKLALIGPSGSGK
                     TTILRILMTLETISEGFIQVEGEELYHVKKAGNLVPADERHLHKMREKIGMVFQHFNL
                     FPHKCVLDNVTLAPMLTKGMARADAQKRAMELLDMVGLADKAKSMPAQLSGGQKQRVA
                     IARALALSPKIMLFDEVTSALDPELVEEVLNVMRKLAAETDMTMLLVTHEMGFAHDFA
                     DRVLFFDRGKIVEEGKPEEIFRHPKQERTQTFLRKIIAAGHRV"
     misc_feature    complement(140756..141508)
                     /locus_tag="Smed_3700"
                     /note="ectoine/hydroxyectoine ABC transporter, ATP-binding
                     protein; Region: ectoine_ehuA; TIGR03005"
                     /db_xref="CDD:132050"
     misc_feature    complement(140837..141508)
                     /locus_tag="Smed_3700"
                     /note="ATP-binding cassette domain of the histidine and
                     glutamine transporters; Region: ABC_HisP_GlnQ; cd03262"
                     /db_xref="CDD:213229"
     misc_feature    complement(141389..141412)
                     /locus_tag="Smed_3700"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(order(140897..140899,140996..141001,
                     141230..141232,141386..141394,141398..141403))
                     /locus_tag="Smed_3700"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(141230..141241)
                     /locus_tag="Smed_3700"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(141044..141073)
                     /locus_tag="Smed_3700"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(140996..141013)
                     /locus_tag="Smed_3700"
                     /note="Walker B; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(140978..140989)
                     /locus_tag="Smed_3700"
                     /note="D-loop; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(140891..140911)
                     /locus_tag="Smed_3700"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213229"
     gene            complement(141684..143120)
                     /locus_tag="Smed_3701"
                     /db_xref="GeneID:5318310"
     CDS             complement(141684..143120)
                     /locus_tag="Smed_3701"
                     /note="PFAM: regulatory protein GntR HTH; aminotransferase
                     class I and II;
                     KEGG: sme:SMb20426 hypothetical transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312447.1"
                     /db_xref="GI:150375851"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="GeneID:5318310"
                     /translation="MLTFALSIELILITVQIMTNWTPDTTLLRRPAYLSLADQFARAI
                     QEGRLQNGARLPTHRKLADDLKLSVQTVSRAYDELIRRGLISGEVGRGSFVQTRPREP
                     EPPYLPERLGELIDLSILKPVCEQYHLEKMRQGFAWLAENLPASSALSFRPNMVFPRH
                     RNIAAEWLLRCGLDVSPLNINLTNGATSAMTVALMSVAPPGSTVATEAISHHTLVPLS
                     SYLGIHLNGIAIDRDGMIPDALDEACRKGVVRAVFLQPSVINPTATLMSAERRAALAE
                     VARRHDIAIIENDILGPLVEERLPPVAALAPERTLYVTSFTKITVPGLRIGYLVAPDR
                     YVAAVANRHLVSNWMATPAIAEIATQWVSDGTAIELVNWQRRALASRHVIAKEVLGSL
                     AHHTHPQSLHVWLPLPEGHMEDAFVSQARLRGVAIAPGASFRTADSGWRPAVRISLGS
                     TTEQELRSGLGIVASLALGKPEALLLVI"
     misc_feature    complement(141702..143030)
                     /locus_tag="Smed_3701"
                     /note="Transcriptional regulators containing a DNA-binding
                     HTH domain and an aminotransferase domain (MocR family)
                     and their eukaryotic orthologs [Transcription / Amino acid
                     transport and metabolism]; Region: ARO8; COG1167"
                     /db_xref="CDD:224089"
     misc_feature    complement(142836..143030)
                     /locus_tag="Smed_3701"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(142842..142853,142857..142862,
                     142890..142892,142899..142904,142908..142922,
                     142944..142949,142953..142955,143022..143024,
                     143028..143030))
                     /locus_tag="Smed_3701"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(141759..142706)
                     /locus_tag="Smed_3701"
                     /note="Aspartate aminotransferase family. This family
                     belongs to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). Pyridoxal phosphate
                     combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine...; Region: AAT_like;
                     cd00609"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(142146..142148,142167..142172,
                     142176..142178,142248..142250,142341..142343,
                     142488..142490,142560..142568))
                     /locus_tag="Smed_3701"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(142050..142052,142059..142061,
                     142146..142154,142269..142271,142458..142460,
                     142557..142559))
                     /locus_tag="Smed_3701"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99734"
     misc_feature    complement(142167..142169)
                     /locus_tag="Smed_3701"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
     gene            143174..143827
                     /locus_tag="Smed_3702"
                     /db_xref="GeneID:5318311"
     CDS             143174..143827
                     /locus_tag="Smed_3702"
                     /note="PFAM: regulatory protein AsnC/Lrp family;
                     KEGG: sme:SMb20425 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="AsnC family transcriptional regulator"
                     /protein_id="YP_001312448.1"
                     /db_xref="GI:150375852"
                     /db_xref="InterPro:IPR000485"
                     /db_xref="GeneID:5318311"
                     /translation="MKLDAIDLRILEAIQADGRITKLALAEKAGLSPTPCWMRLRKLE
                     KAGIVTGYHARVALRRVAPVASVMMEITLGNHRQADFDRFERAIAAIPEIVACWSVGG
                     GVDYILKIMTADIDAYQRLVDGLLERTRHRSIFHLHRHEDGQGRDRPAARLAVAASVG
                     WAGLGDTGRSPGNGARDSQSLPPLPPLWSKSLPCPVRLDNLSPQRWHSSLNSRGEPL"
     misc_feature    143180..143509
                     /locus_tag="Smed_3702"
                     /note="helix_turn_helix ASNC type; Region: HTH_ASNC;
                     smart00344"
                     /db_xref="CDD:214628"
     misc_feature    143183..>143329
                     /locus_tag="Smed_3702"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cd00090"
                     /db_xref="CDD:238042"
     misc_feature    order(143186..143194,143234..143242,143267..143278,
                     143282..143287,143294..143299,143303..143308,
                     143324..143329)
                     /locus_tag="Smed_3702"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238042"
     misc_feature    order(143234..143236,143243..143245)
                     /locus_tag="Smed_3702"
                     /note="putative Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    143378..>143557
                     /locus_tag="Smed_3702"
                     /note="AsnC family; Region: AsnC_trans_reg; pfam01037"
                     /db_xref="CDD:216258"
     gene            143824..145320
                     /locus_tag="Smed_3703"
                     /db_xref="GeneID:5318423"
     CDS             143824..145320
                     /locus_tag="Smed_3703"
                     /note="PFAM: aldehyde dehydrogenase;
                     KEGG: sme:SMb20424 putative succinate-semialdehyde
                     dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="YP_001312449.1"
                     /db_xref="GI:150375853"
                     /db_xref="InterPro:IPR002086"
                     /db_xref="GeneID:5318423"
                     /translation="MTAIFARTAFHDALKKLNDRQLLRELAYVGGRWVAGREGSSLEV
                     SDPASGASLAFVASLDAAQTSEAIDAAEKAFSSWRNMLPQARAAILRKWHGLMLDARE
                     DLALLMTLEQGKPLAESRGEIEYAASFIEWYAEEGKRLNAESVTSHLADAEMIVRREA
                     LGVVGIVTPWNFPSAMITRKAAAALAAGCTVVAHPSSETPLSALALAELGERAGLPAG
                     VFNVVTGKAATIVGRMCEDARVRAMSFTGSTEIGRLIASQCAPTMKRLVMELGGHAPL
                     IVFADANVEKAADIAIAAKFATSGQDCLAANRIYVERPVLKAFQEAFAARIARLEVGS
                     GMEPGTDIGPLMHERAVAKVEEQVADALKSGARLSAGGKRHAAGPLFFQPTLLTDVPD
                     DALIMREETFGPVAAISAFDSEDEVVARANDTEYGLVAYVVTDNGARQMRLARALEYG
                     MVAINRVKITGGPIPFGGWKQSGLGREGSRHGMEAFTELKYLCIDTAA"
     misc_feature    143860..145305
                     /locus_tag="Smed_3703"
                     /note="succinic semialdehyde dehydrogenase; Region:
                     PLN02278"
                     /db_xref="CDD:215157"
     misc_feature    143953..145305
                     /locus_tag="Smed_3703"
                     /note="Mitochondrial succinate-semialdehyde dehydrogenase
                     and ALDH family members 5A1 and 5F1-like; Region:
                     ALDH_F5_SSADH_GabD; cd07103"
                     /db_xref="CDD:143421"
     misc_feature    order(144067..144069,144094..144096,144217..144219,
                     144226..144231,144235..144261,144277..144285,
                     144298..144300,144544..144546,144580..144582,
                     144592..144594,144601..144603,144772..144774,
                     144784..144786,144922..144924,145126..145128,
                     145132..145137,145147..145149,145153..145155,
                     145162..145164,145168..145188,145204..145206,
                     145213..145218,145234..145236,145249..145251,
                     145285..145305)
                     /locus_tag="Smed_3703"
                     /note="tetramerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:143421"
     misc_feature    order(144322..144336,144358..144360,144403..144405,
                     144409..144414,144556..144567,144574..144576,
                     144583..144588,144628..144636,144730..144732,
                     145021..145023,145027..145029,145105..145107,
                     145219..145221)
                     /locus_tag="Smed_3703"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:143421"
     misc_feature    order(144334..144336,144628..144630,144721..144723,
                     144730..144732)
                     /locus_tag="Smed_3703"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143421"
     gene            145403..146779
                     /locus_tag="Smed_3704"
                     /db_xref="GeneID:5318424"
     CDS             145403..146779
                     /locus_tag="Smed_3704"
                     /note="PFAM: aminotransferase class-III;
                     KEGG: sme:SMb20423 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312450.1"
                     /db_xref="GI:150375854"
                     /db_xref="InterPro:IPR005814"
                     /db_xref="GeneID:5318424"
                     /translation="MLENSNELTAWDRDHFFHPSTHMGMHARGETPTRVIGGGEGVYI
                     TDISGKRSLDAFAGLYCVNVGYGRQKIADAIAEQAKNLAYYHAYVGHGTEASIRLSKM
                     IIDRAPEGMSRVYFGLSGSDANETNIKLIWYYNNILGRPEKKKIISRWRGYHGSGVMT
                     GSLTGLHLFHNAFDLPRAPILHTEAPYYFRRPDRSMSEEQFSQYCAEKLEEMILAEGP
                     DTVAAFIGEPILGTGGIVPPPKGYWEKIQGVLQKYDILLVADEVVTGFGRLGTMFGSD
                     HYGIKPDLITIAKGLTSAYAPLSGTIVADKVWQVLVKGSNELGAIGHGWTYSAHPICA
                     AAGIANLELIDELGIVENAGTTGAYFREELQKAIGDHRNVGEVRGDGLMAAIEFVEDR
                     DDRAFFDPGRKIGPQVATALLERGVIGRAMPQGDILGFAPPLCLTRDEADIVVKAATD
                     AIQSVFDR"
     misc_feature    145403..146776
                     /locus_tag="Smed_3704"
                     /note="hypothetical protein; Provisional; Region:
                     PRK07482"
                     /db_xref="CDD:236026"
     misc_feature    145424..146758
                     /locus_tag="Smed_3704"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     Region: OAT_like; cd00610"
                     /db_xref="CDD:99735"
     misc_feature    order(145757..145765,145859..145864,145868..145870,
                     146081..146083,146180..146182,146186..146191,
                     146267..146269)
                     /locus_tag="Smed_3704"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99735"
     misc_feature    order(145760..145765,145859..145864,146081..146083,
                     146180..146182,146189..146191,146267..146269)
                     /locus_tag="Smed_3704"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99735"
     misc_feature    146267..146269
                     /locus_tag="Smed_3704"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     gene            146791..147864
                     /locus_tag="Smed_3705"
                     /db_xref="GeneID:5318425"
     CDS             146791..147864
                     /locus_tag="Smed_3705"
                     /note="PFAM: Alcohol dehydrogenase zinc-binding domain
                     protein; Alcohol dehydrogenase GroES domain protein;
                     KEGG: sme:SMb20422 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="YP_001312451.1"
                     /db_xref="GI:150375855"
                     /db_xref="InterPro:IPR002364"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="GeneID:5318425"
                     /translation="MIGSIPDAMAAVRLTGHGGLDKLVYSRDVPVPAPAAGEVLIKVT
                     ACGMNNTDVWVREGAYGTEDDPSAVSTWRRQGNTLTFPRIQGTDTVGHIVAVGEGVDE
                     ARIGERVMVDFSIYNRDDDSLADIDYMGHGRDGGYAEYMALPAENAHVVATDLTDIEL
                     ATFCCAYLTGERMLERARLAAGETVLVTGASGGVGSAIIQLARARGAVPIAVAGPGKE
                     AAMLEIGAEAVVTRGQGNLAEAVETAGGGRPIDVVADLVGGPLFNDLLKILRPEGRYT
                     TAGAIAGPVVQLDLRTMYLKQLELHGSSQGSRADFLRLVRYIEEKKIRPLVGGVYRLS
                     QFHRAQTDFMAKNFVGKLVVVPD"
     misc_feature    146815..147858
                     /locus_tag="Smed_3705"
                     /note="Medium chain dehydrogenases/reductase
                     (MDR)/zinc-dependent alcohol dehydrogenase-like family;
                     Region: MDR9; cd08274"
                     /db_xref="CDD:176235"
     misc_feature    146815..147858
                     /locus_tag="Smed_3705"
                     /note="NADPH:quinone reductase and related Zn-dependent
                     oxidoreductases [Energy production and conversion /
                     General function prediction only]; Region: Qor; COG0604"
                     /db_xref="CDD:223677"
     misc_feature    order(146935..146943,146950..146952,147283..147285,
                     147295..147297,147355..147366,147370..147375,
                     147430..147435,147439..147441,147484..147486,
                     147556..147561,147565..147567,147622..147627,
                     147697..147705)
                     /locus_tag="Smed_3705"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176235"
     gene            complement(147916..148548)
                     /locus_tag="Smed_3706"
                     /db_xref="GeneID:5318426"
     CDS             complement(147916..148548)
                     /locus_tag="Smed_3706"
                     /note="PFAM: Glutathione S-transferase domain;
                     KEGG: sme:SMb20420 putative glutathione S-transferase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase domain-containing
                     protein"
                     /protein_id="YP_001312452.1"
                     /db_xref="GI:150375856"
                     /db_xref="InterPro:IPR004045"
                     /db_xref="InterPro:IPR004046"
                     /db_xref="GeneID:5318426"
                     /translation="MMKLYGLGPTRSLRALWALRELDAEFEFVPVNILGGEARHPDFL
                     RLNPAGKLPVLVDGDFILTESAAIVMYLAEKYGAKGLMPTDLKERAQAYRWTLFAVTE
                     LEQPLWRIAKHEFLYPENKRLPEDVALAREEFLAMAAVLERHMDGREFIVGERMTIAD
                     CVTAYVLDWGNENALIDGFSNLKAYFERMYARPRAPQRIAEAMADLQQVA"
     misc_feature    complement(147931..148545)
                     /locus_tag="Smed_3706"
                     /note="Glutathione S-transferase [Posttranslational
                     modification, protein turnover, chaperones]; Region: Gst;
                     COG0625"
                     /db_xref="CDD:223698"
     misc_feature    complement(148318..148545)
                     /locus_tag="Smed_3706"
                     /note="GST_N family, Saccharomyces cerevisiae GTT1-like
                     subfamily; composed of predominantly uncharacterized
                     proteins with similarity to the S. cerevisiae GST protein,
                     GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are
                     cytosolic dimeric proteins involved...; Region:
                     GST_N_GTT1_like; cd03046"
                     /db_xref="CDD:239344"
     misc_feature    complement(order(148339..148344,148351..148353,
                     148486..148491,148498..148503,148507..148512,
                     148516..148518))
                     /locus_tag="Smed_3706"
                     /note="putative C-terminal domain interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239344"
     misc_feature    complement(order(148354..148359,148390..148398,
                     148516..148518))
                     /locus_tag="Smed_3706"
                     /note="putative GSH binding site (G-site) [chemical
                     binding]; other site"
                     /db_xref="CDD:239344"
     misc_feature    complement(order(148339..148341,148348..148353,
                     148357..148362,148396..148398))
                     /locus_tag="Smed_3706"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239344"
     misc_feature    complement(147970..148275)
                     /locus_tag="Smed_3706"
                     /note="C-terminal, alpha helical domain of an unknown
                     subfamily 8 of Glutathione S-transferases; Region:
                     GST_C_8; cd03207"
                     /db_xref="CDD:198316"
     misc_feature    complement(order(148117..148119,148129..148131,
                     148138..148140,148162..148164,148171..148173,
                     148222..148224,148240..148251,148255..148260,
                     148264..148269))
                     /locus_tag="Smed_3706"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:198316"
     misc_feature    complement(order(148042..148047,148054..148059,
                     148063..148068,148075..148083,148225..148227,
                     148237..148239,148249..148251,148261..148263))
                     /locus_tag="Smed_3706"
                     /note="N-terminal domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:198316"
     misc_feature    complement(order(148042..148044,148051..148053,
                     148222..148227,148234..148239,148249..148251))
                     /locus_tag="Smed_3706"
                     /note="putative substrate binding pocket (H-site)
                     [chemical binding]; other site"
                     /db_xref="CDD:198316"
     gene            complement(148673..149722)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /db_xref="GeneID:5318427"
     CDS             complement(148673..149722)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="part of the UgpABCE glycerol-3-phosphate uptake
                     system"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter ATP-binding
                     subunit"
                     /protein_id="YP_001312453.1"
                     /db_xref="GI:150375857"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005116"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5318427"
                     /translation="MATINLTDVHKTYQGDIAAIRGVSLAIADGEFIVLVGPSGCGKS
                     TLLRMIAGLESITSGEVSIGDRVVNGLEPSERDIAMVFQNYALYPHMTVRQNLSYGLK
                     NRNTPKDEIERRIAKAAKSLEIEPFLDRKPRQLSGGQRQRVAMGRAIVREPAAFLFDE
                     PLSNLDAKLRVQMRVEIRRLQRALATTSVYVTHDQLEAMTLADRLVVLNGGRIEQVGT
                     PIELYEKPATAFVATFIGSPSMNLLDIGSHDSAWTVPGGLVGKPGLATIGIRPEDITL
                     ADGSAGGDRFRARVRVGAVELVGAESYVHGTLTNGEPLVFRVAGRSRTAIDEELEVAA
                     EPESLHWFDAAGRRL"
     misc_feature    complement(148679..149722)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="glycerol-3-phosphate transporter ATP-binding
                     subunit; Provisional; Region: ugpC; PRK11650"
                     /db_xref="CDD:236947"
     misc_feature    complement(149072..149713)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    complement(149591..149614)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(order(149144..149146,149243..149248,
                     149474..149476,149588..149596,149600..149605))
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(149474..149485)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(149291..149320)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(149243..149260)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(149225..149236)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(149138..149158)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(148697..148924)
                     /gene="ugpC"
                     /locus_tag="Smed_3707"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            complement(149722..150570)
                     /locus_tag="Smed_3708"
                     /db_xref="GeneID:5318428"
     CDS             complement(149722..150570)
                     /locus_tag="Smed_3708"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20418 probable glycerol-3-phosphate ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312454.1"
                     /db_xref="GI:150375858"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318428"
                     /translation="MIEKRPISSLIGHLMLIIGVIIVVFPIYYTFVASSMSSVEIIRP
                     PMPLVPGSRLIENYSEALSGGVERVVGVSLERLLFNTFVVAVAIAAGKIVISFLSAFA
                     IVFFRFPLRMVFFWMIFITLMLPVEVRILPTYKVIVDLGLIDTYAGLTLPLMASATAT
                     FLFRQFFLTIPGELVEAARIDNAGPFRFMRDILLPLSKTNIAALFVILFIYGWTQYLW
                     PLLVTNDSRMNTIIIGLRKMVDFTDASTPWNYVMVTAILAIIPPVAVVVLMQRWFVKG
                     LVETEK"
     misc_feature    complement(149731..150561)
                     /locus_tag="Smed_3708"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    complement(149887..150285)
                     /locus_tag="Smed_3708"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(149908..149913,149920..149931,
                     149950..149952,149959..149964,150004..150006,
                     150055..150057,150064..150069,150079..150081,
                     150085..150090,150097..150099,150103..150105,
                     150109..150114,150169..150171,150175..150180,
                     150187..150216,150220..150231,150259..150261,
                     150274..150279))
                     /locus_tag="Smed_3708"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(149914..149931,150169..150213))
                     /locus_tag="Smed_3708"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(149983..149985,149995..150000,
                     150016..150054))
                     /locus_tag="Smed_3708"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(150579..151460)
                     /locus_tag="Smed_3709"
                     /db_xref="GeneID:5318429"
     CDS             complement(150579..151460)
                     /locus_tag="Smed_3709"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20417 probable glycerol-3-phosphate ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312455.1"
                     /db_xref="GI:150375859"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318429"
                     /translation="MQRVVFPNKILPYLLVAPQIALTIVFFFWPASQALYQSVIREDP
                     FGLKSGFVGFANFSAVLSEPNYLNSLKVTVIFSVLTALLAMAVALLLATAADRVVRGQ
                     AFYRTLLIWPYAVAPAVAGMLWLFMFNPAMGTFAYMLRRSGFHWDPLLNGNHAMILIV
                     VAAAWKQISYNFLFFVAGLQAIPKSLIEAAAIDGARGTRRFWTIVFPLLAPTTFFLLV
                     VNTVYAFFDTFGIIHSVTGGGPARATETLVYKVYNDGFVNLNLGSSAAQSVILMAIVI
                     GLTAFQFRFVEKRVHYG"
     misc_feature    complement(<151077..151448)
                     /locus_tag="Smed_3709"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cl00427"
                     /db_xref="CDD:241857"
     misc_feature    complement(150591..151439)
                     /locus_tag="Smed_3709"
                     /note="ABC-type polysaccharide transport system, permease
                     component [Carbohydrate transport and metabolism]; Region:
                     LplB; COG4209"
                     /db_xref="CDD:226666"
     misc_feature    complement(150633..151163)
                     /locus_tag="Smed_3709"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(150633..150638,150645..150650,
                     150657..150662,150666..150671,150678..150683,
                     150714..150719,150756..150761,150774..150785,
                     150804..150806,150813..150818,150858..150860,
                     150909..150911,150918..150923,150933..150935,
                     150939..150944,150951..150953,150957..150959,
                     150966..150971,151086..151088,151092..151097,
                     151104..151133,151137..151148))
                     /locus_tag="Smed_3709"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(150768..150785,151086..151130))
                     /locus_tag="Smed_3709"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(150681..150683,150714..150716,
                     150723..150725,150759..150761,150984..150986,
                     151086..151088))
                     /locus_tag="Smed_3709"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(150837..150839,150849..150854,
                     150870..150908))
                     /locus_tag="Smed_3709"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(151577..152872)
                     /locus_tag="Smed_3710"
                     /db_xref="GeneID:5318430"
     CDS             complement(151577..152872)
                     /locus_tag="Smed_3710"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb20416 probable ABC transporter periplasmic
                     glycerol-3-phosphate-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312456.1"
                     /db_xref="GI:150375860"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5318430"
                     /translation="MRVISISTTMAVVGFAVQAQAATELQWWHAMTGANNEMIEELTK
                     EFNASQSTYKVVPVFKGTYPETLNAGIAAFRSKQPPAIIQVFDAGSGTMMAAEGAIVP
                     AAEILQKGGFTFDKSQYLPGIVAYYSKPDGTMLSFPYNSSSPILYYNKDAFQKAGLNV
                     DNPPKTWPEVFEAAKKIKTSGAAPCGMTSTWLTWIQTENFAAWNNMPYGTNENGLGGT
                     DVQLKINAPLYVEHFQAIANLAKDGAFRYGGRTSEAKQLFTSGECAILTESSGGLGDI
                     AKSGVNYGIGQLPYYEGHGPQNTIPGGASLWVFAGKSDEEYKGIAEFFNFLSQTEIQA
                     KLHQVSGYMPVTMAAYEETKKSGFYEKNPGRETPLLQMMGKAPTENSKGVRLVNLPQV
                     RDILNEEFEAMLSGQQDAKTALDKAVERGDAAIAAAISN"
     sig_peptide     complement(152807..152872)
                     /locus_tag="Smed_3710"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.961 at
                     residue 22"
     misc_feature    complement(151598..152806)
                     /locus_tag="Smed_3710"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     misc_feature    complement(151607..152806)
                     /locus_tag="Smed_3710"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; cl17199"
                     /db_xref="CDD:247753"
     gene            153238..154527
                     /locus_tag="Smed_3711"
                     /db_xref="GeneID:5318431"
     CDS             153238..154527
                     /locus_tag="Smed_3711"
                     /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase;
                     dTDP-4-dehydrorhamnose reductase; Male sterility domain;
                     KEGG: sme:SMb20415 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="YP_001312457.1"
                     /db_xref="GI:150375861"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318431"
                     /translation="MMRVLVVGASGLIGSAVCAGLHERGMEVVRVVRPGSAPSSATAG
                     QTLEVDLRNAGPEAWRPHLPDIDAVVNCAGTLQDGPGEDTEAVHARGPASLFRACEQA
                     GVRRVVHFSAMGVDKAQPSPFSRTKLEGDEALMACDLDWVILRPSVVLGPGAYGASAL
                     FRGLAALPWLPLMPNTGLLQVVRLEDVVRTVALFVGPDAPARLALEVAGPEALTFKDV
                     VSTYRRWFGWPAAPVVNVPTPLAGLTYSLSDLAGALGWRPPTRSTAQKEIVRGAVGDA
                     RAWIEKTGIEPLALSDALTRTPVSVQERWFAKLYLLKPVIFIVLSLFWIMTGVISLTS
                     GYEIGVDLMERGGAGVLAGPSVIAGALADILIGTAIALRRTSRIGLYGAVALSLFYAV
                     AGTVLLPELWNEPLGPLLKIWPILVLHLAALAILEER"
     sig_peptide     153238..153297
                     /locus_tag="Smed_3711"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.800) with cleavage site probability 0.646 at
                     residue 20"
     misc_feature    153241..154107
                     /locus_tag="Smed_3711"
                     /note="Predicted nucleoside-diphosphate-sugar epimerases
                     [Cell envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: COG0702"
                     /db_xref="CDD:223774"
     misc_feature    153241..154020
                     /locus_tag="Smed_3711"
                     /note="NADH dehydrogenase (ubiquinone) 1 alpha subcomplex,
                     subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs;
                     Region: NDUFA9_like_SDR_a; cd05271"
                     /db_xref="CDD:187579"
     misc_feature    order(153259..153261,153265..153276,153331..153336,
                     153451..153459,153496..153498,153565..153573,
                     153604..153606,153616..153618,153673..153684)
                     /locus_tag="Smed_3711"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187579"
     misc_feature    order(153604..153606,153616..153618)
                     /locus_tag="Smed_3711"
                     /note="active site"
                     /db_xref="CDD:187579"
     misc_feature    154198..154479
                     /locus_tag="Smed_3711"
                     /note="DoxX-like family; Region: DoxX_3; pfam13781"
                     /db_xref="CDD:222376"
     gene            154527..155000
                     /locus_tag="Smed_3712"
                     /db_xref="GeneID:5318525"
     CDS             154527..155000
                     /locus_tag="Smed_3712"
                     /note="KEGG: sme:SMb20414 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312458.1"
                     /db_xref="GI:150375862"
                     /db_xref="GeneID:5318525"
                     /translation="MLYFVLKFLHIIGASVLLGTGAGIAFFMLLAHRTGRTETVAAVA
                     RIVVIADFLFTATAVVLQPVTGIALAWNVGYSLAEGWIVLSIFLYLITGAFWLPVVWM
                     QMEMRRLAEAASKAGNPLPKRYHQLFRLWFAFGFPAFGAVVAIFWLMITRPALAW"
     misc_feature    154527..154991
                     /locus_tag="Smed_3712"
                     /note="Predicted integral membrane protein [Function
                     unknown]; Region: COG5528"
                     /db_xref="CDD:227815"
     sig_peptide     154527..154622
                     /locus_tag="Smed_3712"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.826) with cleavage site probability 0.805 at
                     residue 32"
     gene            complement(155064..156074)
                     /locus_tag="Smed_3713"
                     /db_xref="GeneID:5318526"
     CDS             complement(155064..156074)
                     /locus_tag="Smed_3713"
                     /note="PFAM: Substrate-binding region of ABC-type glycine
                     betaine transport system;
                     KEGG: sme:SMb20410 putative glycine-betaine-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="YP_001312459.1"
                     /db_xref="GI:150375863"
                     /db_xref="InterPro:IPR007210"
                     /db_xref="GeneID:5318526"
                     /translation="MSRLSGLLTCVSQCIQNLRRGNMTMLKQITAMTTGLLMTIGVAN
                     AAEPESCKTVRFSDVGWTDITSTTAVASTILEALGYAPESKLLSIPVTYASMKNKDID
                     VYLGDWQPSMEADRKSFLEDKSIEVIGPNLTGAKYTFAVPKYVADAGVKDISDLQKFA
                     DKFGRKIYGIEPGNNGNRMILDMINKGDFGLTGWELVESSEQGMLAEVERATKDEQWI
                     VFLGWAPHPMNTRYRIDYLSGADAYFGPNYGGADIYTNIRAGYAQECPNVARFVTNLR
                     FTLDMENEIMNGILNDGKDPKEAAADWLKAHPDAVAPWLEGVTTYDGGPAAGAVEMAL
                     KS"
     sig_peptide     complement(155937..156074)
                     /locus_tag="Smed_3713"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.988) with cleavage site probability 0.988 at
                     residue 46"
     misc_feature    complement(155106..156011)
                     /locus_tag="Smed_3713"
                     /note="ABC-type proline/glycine betaine transport systems,
                     periplasmic components [Amino acid transport and
                     metabolism]; Region: ProX; COG2113"
                     /db_xref="CDD:225024"
     misc_feature    complement(155073..155942)
                     /locus_tag="Smed_3713"
                     /note="choline ABC transporter, periplasmic binding
                     protein; Region: ABC_choline_bnd; TIGR03414"
                     /db_xref="CDD:188316"
     gene            complement(156071..156901)
                     /locus_tag="Smed_3714"
                     /db_xref="GeneID:5318527"
     CDS             complement(156071..156901)
                     /locus_tag="Smed_3714"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR; KR
                     domain protein;
                     KEGG: sme:SMb20409 putative hydroxybutyrate dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001312460.1"
                     /db_xref="GI:150375864"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5318527"
                     /translation="MTGRLKGRSAVITGGLTGQGLAIAEAFAADGANVAVGSFVREAS
                     GRQGDAAAYPDPREIAEIRVRLAAAGTAVHAGHLDVRDSEAIEQFVAAAEAACGPTDI
                     LVNAAGTTAEQPVSGHSDELWLKIIDTNLNGAFRMTRRLLPGMIGRKWGRIINIGSTA
                     ATVGWKDNPAYCASKSGLLGLTRCVALEGAPHGVTCVMISPTWVETELMRRNVRQVVE
                     REGSGRTTEEAMADIAAQNPQNRIIQPDEIAALAAFLCGEGARGITMENIQITGGALW
                     "
     sig_peptide     complement(156815..156901)
                     /locus_tag="Smed_3714"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.919) with cleavage site probability 0.556 at
                     residue 29"
     misc_feature    complement(156074..156898)
                     /locus_tag="Smed_3714"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Provisional; Region: fabG; PRK12825"
                     /db_xref="CDD:237218"
     misc_feature    complement(156089..156874)
                     /locus_tag="Smed_3714"
                     /note="classical (c) SDRs; Region: SDR_c; cd05233"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(156281..156286,156290..156301,
                     156377..156379,156389..156391,156428..156436,
                     156515..156517,156578..156586,156662..156670,
                     156761..156769,156845..156856,156860..156862))
                     /locus_tag="Smed_3714"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(156377..156379,156389..156391,
                     156428..156430,156512..156514))
                     /locus_tag="Smed_3714"
                     /note="active site"
                     /db_xref="CDD:212491"
     gene            complement(156898..157395)
                     /locus_tag="Smed_3715"
                     /db_xref="GeneID:5318528"
     CDS             complement(156898..157395)
                     /locus_tag="Smed_3715"
                     /note="PFAM: Acetone carboxylase gamma subunit;
                     KEGG: sme:SMb20408 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acetone carboxylase subunit gamma"
                     /protein_id="YP_001312461.1"
                     /db_xref="GI:150375865"
                     /db_xref="InterPro:IPR014979"
                     /db_xref="GeneID:5318528"
                     /translation="MTTYSKEIINDLVNGTLPWPQTRRIMSAYKDDDRFFKYLAVLQD
                     RVAWAEAVLLPVGDRLFICDSAEGRITRCECGYSFGDYRKNWKLKAAINVRDTEESLR
                     EIYPNSDIPDSQWMEIREFFCPECAHLHEVEAAAPGYPIVHDFEPDLEGFYRDWLGKP
                     LKDQS"
     misc_feature    complement(156901..157395)
                     /locus_tag="Smed_3715"
                     /note="Acetone carboxylase, gamma subunit [Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: AcxC; COG4647"
                     /db_xref="CDD:226994"
     misc_feature    complement(156922..157260)
                     /locus_tag="Smed_3715"
                     /note="Acetone carboxylase gamma subunit; Region:
                     Acetone_carb_G; pfam08882"
                     /db_xref="CDD:149823"
     gene            complement(157399..159591)
                     /locus_tag="Smed_3716"
                     /db_xref="GeneID:5318529"
     CDS             complement(157399..159591)
                     /locus_tag="Smed_3716"
                     /note="PFAM: Hydantoinase B/oxoprolinase;
                     KEGG: sme:SMb20407 putative N-methylhydantoinase,
                     hydantoin utiliztion protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase B/oxoprolinase"
                     /protein_id="YP_001312462.1"
                     /db_xref="GI:150375866"
                     /db_xref="InterPro:IPR003692"
                     /db_xref="GeneID:5318529"
                     /translation="MLDKTANPLQRRLLESERLMEETGCYDGITELRLRGQDPLKFET
                     LHTKLRAYCVSAREMARRISASPGVREVGEMVVAIYTPEGDAIALSNGIMVHVHTMSR
                     FIKWMIRNGYEQNPCIRDGDIFANNDAFIGTVQVPDVMDVVPIFHEGTLVGWAGAVCH
                     ELEAGGITPGGDVCLAQERFTEGLFVCAEKIGENDEIRRDYVIRCERNLRMPIYWVLD
                     EKAKVAACIDMRENVKQLIEEIGLEYWQRLSKEFIEEGRRAQLARTRQLTVPGIYRGH
                     TFYGHVTEGKPGFQPLADPNWLYNIPIEMEITSEGKIRLDFDGTQPWGYHSMNCTPAG
                     MDGGMFVTLTQHMNFEGLVNDGAWLATEINIPHGTWTNPDNEMAATATSWALLLPAYG
                     VFQRLLSRGFIARGFVEEAFVGQVNSPMIEMGGTSQYGTGFGMAHFECAAAGSGALAI
                     KDGLDTAYVGWNPESDMGNIEIWEQNMPMVYIGRSIVPNSGGAGKYRGGCAFISTWLI
                     NKTDHLRLVTSEHSSRVFDNGGLCGGYPAPTCEKHHAVRNSDIHERAERREPLAHTPG
                     TDPLVSDFERIYKGEQVWEEGPYITRPHKAGDIFSHAYNGGGGFGDVLERDPIKTAWD
                     VENGFLTREAAEKVFGIILKEDAEGYPQADIDATVARRAEIRRERMRKAIPVSEWMVR
                     EQLRVKASDFAPEVAKMYRSAMKLSPRFSKDFREFWGLASDFTIAGEN"
     misc_feature    complement(157648..159483)
                     /locus_tag="Smed_3716"
                     /note="N-methylhydantoinase B/acetone carboxylase, alpha
                     subunit [Amino acid transport and metabolism / Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: HyuB; COG0146"
                     /db_xref="CDD:223224"
     misc_feature    complement(157759..159480)
                     /locus_tag="Smed_3716"
                     /note="Hydantoinase B/oxoprolinase; Region:
                     Hydantoinase_B; pfam02538"
                     /db_xref="CDD:217092"
     gene            complement(159609..161738)
                     /locus_tag="Smed_3717"
                     /db_xref="GeneID:5318530"
     CDS             complement(159609..161738)
                     /locus_tag="Smed_3717"
                     /EC_number="3.5.2.9"
                     /note="PFAM: Hydantoinase/oxoprolinase;
                     Hydantoinaseoxoprolinase domain protein;
                     KEGG: sme:SMb20406 putative hydantoin utilization protein
                     A"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase"
                     /protein_id="YP_001312463.1"
                     /db_xref="GI:150375867"
                     /db_xref="InterPro:IPR000834"
                     /db_xref="InterPro:IPR002821"
                     /db_xref="InterPro:IPR008040"
                     /db_xref="GeneID:5318530"
                     /translation="MENPIVIGIDAGGTMTDTILVDQNGHFKIGKAATTPKNEAEGFI
                     SSAADAADAWGISLDSLFSGLDVVLYSGTGMLNTLLSRTGRKLGLITTKGLEDMVLMG
                     RGLQAWADYSYADRLHAVTHAHPDPLVPRRRTHGVTERVDHFGDIVLPLYEHEVTAAA
                     RALIRDKVDAICIMTIFSHVNPVHEKRIAEICREEVAAAGAEINIYTSHEVRPVIREQ
                     SRLNSVLIEAYATSRGRKQLRGIQEASQKYGFKYGVQTLLSFGGLTSINHPRLHETMI
                     SGPIGGILGAAYIGKLIGNDSLICSDMGGTSFDMGVISRGQTRIENEPLMDRFKLNVP
                     TLHLDTIGAGAGMILKVDPLTRKVSLGPESAGADPGPICFAKGGTDPTIADCDAILGR
                     LNPHYFLGGKVVLEVEKARAAFKEKCADVLGVGLEEAAEGMIEMLEQDANNALRRVIS
                     GQGIHPSEFTLLSYGGSGPLHLAGCSRGIGFKDIITFQFAAAFSAFGCTTADYMRRHS
                     VSTQIDIGAHASDDRLAAAGAQVTQVWKDLEKAAVDEMLIDGHAREKIKAVPFFMARY
                     TGQLEDVEVLAPLPSIDTAGDMRAVLAQFEDVYAKANHRVSKYGEAGFSLMELGVIAT
                     AEKIKPVLVRRPLGTADPRSAHKGMREAYIGGRWHKADLYEMDLLEPGHEVIGPAIIE
                     HPATTLVVHPNDRVFIDEWTLLHYNHA"
     misc_feature    complement(159612..161729)
                     /locus_tag="Smed_3717"
                     /note="N-methylhydantoinase A/acetone carboxylase, beta
                     subunit [Amino acid transport and metabolism / Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: HyuA; COG0145"
                     /db_xref="CDD:223223"
     misc_feature    complement(161154..161720)
                     /locus_tag="Smed_3717"
                     /note="Hydantoinase/oxoprolinase N-terminal region;
                     Region: Hydant_A_N; pfam05378"
                     /db_xref="CDD:218571"
     misc_feature    complement(160218..161081)
                     /locus_tag="Smed_3717"
                     /note="Hydantoinase/oxoprolinase; Region: Hydantoinase_A;
                     pfam01968"
                     /db_xref="CDD:216816"
     gene            161836..162630
                     /locus_tag="Smed_3718"
                     /db_xref="GeneID:5318531"
     CDS             161836..162630
                     /locus_tag="Smed_3718"
                     /note="PFAM: regulatory protein LuxR; Sigma-70 region 4
                     type 2;
                     KEGG: sme:SMb20405 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver protein"
                     /protein_id="YP_001312464.1"
                     /db_xref="GI:150375868"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR013249"
                     /db_xref="GeneID:5318531"
                     /translation="MVDEHMSGDVFWNILAQAISATGTDRHVDRLIDMVGAVVPQNLI
                     TVTRYSATRRPEFIKHRGYSDEMVARYLDTYYVFDPFYAYWRLTRRAGIVPLKSLADG
                     APKRGRYIAEFLAQSEICDEVGILLEDGDDWCLGIFLDRSTSMFSDGEVAALSGRFPV
                     FEALHATDTRTRDPNLRRTSMPEAMGEAPVNAVQASLILWPGLTARERELVDLILQGH
                     PNATIASRLGIAPGTVKNHRARIYEKLDITTERELFLQVFQQYRLS"
     misc_feature    <162442..162612
                     /locus_tag="Smed_3718"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    162442..162597
                     /locus_tag="Smed_3718"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    order(162445..162453,162490..162498,162520..162525,
                     162529..162534,162538..162552,162583..162585)
                     /locus_tag="Smed_3718"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    order(162478..162480,162484..162486,162490..162492,
                     162583..162591)
                     /locus_tag="Smed_3718"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            162732..162905
                     /locus_tag="Smed_3719"
                     /db_xref="GeneID:5318532"
     CDS             162732..162905
                     /locus_tag="Smed_3719"
                     /note="KEGG: sme:SMb20401 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312465.1"
                     /db_xref="GI:150375869"
                     /db_xref="GeneID:5318532"
                     /translation="MSKTDVEQAQKDARKQAENTSGGGHLGGTYYGQEPDAKTATTVK
                     KKGDKARPNDGRN"
     gene            complement(163022..163951)
                     /locus_tag="Smed_3720"
                     /db_xref="GeneID:5318533"
     CDS             complement(163022..163951)
                     /locus_tag="Smed_3720"
                     /note="PFAM: transposase IS111A/IS1328/IS1533; transposase
                     IS116/IS110/IS902 family protein;
                     KEGG: hne:HNE_2108 ISHne4, transposase"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS116/IS110/IS902 family protein"
                     /protein_id="YP_001312466.1"
                     /db_xref="GI:150375870"
                     /db_xref="InterPro:IPR002525"
                     /db_xref="InterPro:IPR003346"
                     /db_xref="GeneID:5318533"
                     /translation="MIHPDVIGCDIAKAHLDFFDSGLERHFRIDNTPAAISAWLDGLD
                     GRGVHIVFEATGRYDRQLRIALETRELPYSRVNPARARDFAKAIGLLAKTDAIDARLL
                     ARMGQSLPLSTQADDPARHVLARLHTRRDQLVAMRQQERTRLHETEGIERDSAESHMA
                     WLDAEVARIEMACRDVLKAEKTLQEQEARLRSIPGIGPVAALTLIAHMPELGNRSAKA
                     IAALAGLAPFNVDSGTSRGKRHIRGGRKRIRDALYMAALTASRMPRAFKSHADQMKEA
                     GKPFKVVIIALARKLLAIANAIIRDKTTFRRTT"
     misc_feature    complement(163523..163936)
                     /locus_tag="Smed_3720"
                     /note="Transposase; Region: DEDD_Tnp_IS110; pfam01548"
                     /db_xref="CDD:216564"
     misc_feature    complement(<163334..163807)
                     /locus_tag="Smed_3720"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG3547"
                     /db_xref="CDD:226077"
     misc_feature    complement(163145..163390)
                     /locus_tag="Smed_3720"
                     /note="Transposase IS116/IS110/IS902 family; Region:
                     Transposase_20; pfam02371"
                     /db_xref="CDD:217002"
     gene            164204..164467
                     /locus_tag="Smed_3721"
                     /db_xref="GeneID:5318534"
     CDS             164204..164467
                     /locus_tag="Smed_3721"
                     /note="KEGG: sme:SMb20400 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312467.1"
                     /db_xref="GI:150375871"
                     /db_xref="GeneID:5318534"
                     /translation="MPDYQRLPVRPVPGAMVVKLYRSGDAVRGYVRKVSDPSEDDVIF
                     PGEEMEPDSAFRLAASHREGSLPIYVELVEDVQWDPSWGTLDG"
     gene            complement(164489..165064)
                     /locus_tag="Smed_3722"
                     /db_xref="GeneID:5318588"
     CDS             complement(164489..165064)
                     /locus_tag="Smed_3722"
                     /note="KEGG: sme:SMb20399 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312468.1"
                     /db_xref="GI:150375872"
                     /db_xref="GeneID:5318588"
                     /translation="MQEDLFGYTPTMLEGFRYQAEVVPQKLQEALLGVLPGLSFRPFD
                     FHGYEGKRRVVSFGWKYDFDTESVRKIDDIPSFLLPLRQLAADFAGLPAEKLEQALIT
                     EYDVGAPIGWHRDKAVFGRVVGVSLLAPCTFRLRRRRAGKWERASVALEPGSAYLLSG
                     AARSEWEHSIPPLDGLRYSVTFRELHAGTTG"
     misc_feature    complement(164516..165055)
                     /locus_tag="Smed_3722"
                     /note="Alkylated DNA repair protein [DNA replication,
                     recombination, and repair]; Region: AlkB; COG3145"
                     /db_xref="CDD:225687"
     gene            complement(165169..165705)
                     /locus_tag="Smed_3723"
                     /db_xref="GeneID:5318589"
     CDS             complement(165169..165705)
                     /locus_tag="Smed_3723"
                     /note="PFAM: metallophosphoesterase;
                     KEGG: sme:SMb20398 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="YP_001312469.1"
                     /db_xref="GI:150375873"
                     /db_xref="InterPro:IPR004843"
                     /db_xref="GeneID:5318589"
                     /translation="MFRGVFDYSFAAGEMIYFTGDTHFGDPRVLRIDRRPFSSMAEHD
                     AALTVNWNETVSPQDEVWHLGDFAAKRAGLAQDMLSRLNGRKHLIIGNNDPIDTTAAS
                     GWHSVQHYAELTVDGRLLVLCHYPFRTWNQMGKRSVNLHGHSHGRLKPVPRQFDVGVD
                     ARNLRPVCLAEILPQASR"
     misc_feature    complement(165187..165660)
                     /locus_tag="Smed_3723"
                     /note="Aquifex aeolicus AQ1575 and related proteins,
                     metallophosphatase domain; Region: MPP_AQ1575; cd07390"
                     /db_xref="CDD:163633"
     misc_feature    complement(order(165271..165273,165277..165279,
                     165334..165336,165427..165432,165508..165510,
                     165637..165639,165643..165645))
                     /locus_tag="Smed_3723"
                     /note="putative active site [active]"
                     /db_xref="CDD:163633"
     misc_feature    complement(order(165271..165273,165277..165279,
                     165334..165336,165430..165432,165508..165510,
                     165637..165639,165643..165645))
                     /locus_tag="Smed_3723"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:163633"
     gene            complement(165777..167033)
                     /locus_tag="Smed_3724"
                     /db_xref="GeneID:5318590"
     CDS             complement(165777..167033)
                     /locus_tag="Smed_3724"
                     /note="PFAM: ribulose bisphosphate carboxylase large
                     chain;
                     KEGG: sme:SMb20393 putative ribulose bisphosphate
                     carboxylaseoxygenase, large subunit protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RuBisCO-like protein"
                     /protein_id="YP_001312470.1"
                     /db_xref="GI:150375874"
                     /db_xref="InterPro:IPR000685"
                     /db_xref="GeneID:5318590"
                     /translation="MIHITYRIETPGDVEALARKIASDQSTGTFVAVPGETEELKRRA
                     AARVVAIRHLPPADRASLPDEAGDATRFNRADAEIAYPLEAVGTDLSALMTIAIGGVY
                     AIKGMTGIRVVDMKLPPEFAAAHPGPQFGVAGSRRLTGVEGRPIIGTIVKPALGLLPD
                     ETAALVGDLLSSGVDFIKDDEKLMSPAYSPLSARIAAIMPKIRDHEQKTGKKVMYAFG
                     ISHTDPDEMMRNHDLVVAAGGNAAVVNINSIGMGGVAFLRKRSNLVLHAHRNGWDILT
                     RHGGLGMEFSVWQQFWRLLGVDQFQINGIRVKYWEPDDSFVKSFKAVSTPLFSREDCP
                     LPVVCSGQWGGQAPETFVRTGRTTDLLYLCGGGVVSHPGGAGAGVRAVRQAWEAAVAG
                     IPLSDYAKEHPELAQSIEKFADGKGA"
     misc_feature    complement(165780..167033)
                     /locus_tag="Smed_3724"
                     /note="Ribulose 1,5-bisphosphate carboxylase, large
                     subunit [Carbohydrate transport and metabolism]; Region:
                     RbcL; COG1850"
                     /db_xref="CDD:224763"
     misc_feature    complement(165807..167033)
                     /locus_tag="Smed_3724"
                     /note="Ribulose bisphosphate carboxylase large chain;
                     Region: RuBisCO_large; cl08232"
                     /db_xref="CDD:195661"
     misc_feature    complement(order(166212..166226,166257..166259,
                     166266..166271,166275..166286,166299..166301,
                     166344..166349,166371..166373,166458..166463,
                     166470..166472,166476..166484,166491..166493,
                     166575..166580,166734..166739,166746..166754,
                     166761..166763,166779..166784,166902..166904,
                     166953..166964))
                     /locus_tag="Smed_3724"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:173969"
     misc_feature    complement(166500..166502)
                     /locus_tag="Smed_3724"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:173969"
     misc_feature    complement(166491..166496)
                     /locus_tag="Smed_3724"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:173969"
     gene            167170..167883
                     /locus_tag="Smed_3725"
                     /db_xref="GeneID:5318591"
     CDS             167170..167883
                     /locus_tag="Smed_3725"
                     /note="Transcriptional repressor of the nan operon that
                     encodes proteins involved in sialic acid utilization"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="YP_001312471.1"
                     /db_xref="GI:150375875"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318591"
                     /translation="MAIQSDPIVRRKLSDEVFARLKGSIESGELQPGDEMPSERMLME
                     RFQVGRPAIREAMQALANMGLIEISHGERAKVLQPTARSLLRQVDAAAKIMLAASSDS
                     LEHLKSARIFFERGMAREAASRADAQDIAALEETLKRQRSALEDSDAFIAADMAFHTR
                     IAQISGNPIYTAVSEAMLGWLKEYHTEMLIWTGRENVTLGEHEEIIDCIRRGDPDEAE
                     QAMIRHLERSRTLYARKGR"
     misc_feature    167170..167880
                     /locus_tag="Smed_3725"
                     /note="transcriptional regulator NanR; Provisional;
                     Region: PRK03837"
                     /db_xref="CDD:235166"
     misc_feature    167203..167382
                     /locus_tag="Smed_3725"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    order(167203..167205,167209..167211,167278..167280,
                     167284..167289,167311..167325,167329..167334,
                     167341..167343,167371..167376,167380..167382)
                     /locus_tag="Smed_3725"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    <167299..167481
                     /locus_tag="Smed_3725"
                     /note="Ribosomal protein S19e; Region: Ribosomal_S19e;
                     cl00969"
                     /db_xref="CDD:242225"
     misc_feature    167494..167850
                     /locus_tag="Smed_3725"
                     /note="FCD domain; Region: FCD; pfam07729"
                     /db_xref="CDD:219539"
     gene            complement(167954..169948)
                     /locus_tag="Smed_3726"
                     /db_xref="GeneID:5318592"
     CDS             complement(167954..169948)
                     /locus_tag="Smed_3726"
                     /EC_number="2.4.1.12"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb20391 putative cellulose synthase catalytic
                     subunit protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose synthase"
                     /protein_id="YP_001312472.1"
                     /db_xref="GI:150375876"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR003919"
                     /db_xref="GeneID:5318592"
                     /translation="MVQSLLALAPTLLVLAFFLLGPFNWSRHKSWARAVTCVFVAAIA
                     LRYLIWRFTETVLPYPTDGANFYWVWFVFIAEFLAFSEVVLFLILMSRYVDRSSEADD
                     LERKFFAGNERELPAVDVFIPTYNEPLDVLERTIVGALALDHPKDKLKVYVLDDGRRD
                     WLKTFCEGRGAIHVTRSDNAHAKAGNMNNGLRASSGDFIAVFDADFVPYRSFLRRTLP
                     FFLDETIGIVQTPQHFFNVDPIQSNLGLENLWPDEQRLFFDEIAPSRDGWDVSFCCGS
                     CSIARRKAVDAIGGFPTESITEDLLTTLSMLNRGFKTRYLNERLSMGLAAENLTGYFV
                     QRERWCQGGIQTLYLHNGPLRGPGLSLFQRVMFLPMSWLVQYLVRFIVLLIPIVYLWF
                     GALPLYFTDVADYVSNQVPLLAAYFLLMFWLTPTRYLPLVSTAVGTFSTFRMLPTVLS
                     SLVRPFGKPFKVTPKGSSNEENSFDAYTFTWIAGFIVVTALGLLINIVPETARIEGSF
                     SAIAALWSGINIVVLIIASLICFEKPRRLLQAFKLDEAVKVDGVEGRLVSLSLDKAVV
                     AVSTETRFKSTKVGLNIEGFAPLEADLKQVTQRRGDITRTGDKQRYYLHLHYDLRGAE
                     RDKMIVKLYTGRYSRDVPDIDKIAVSVNLLLRAFGRTRTA"
     sig_peptide     complement(169850..169948)
                     /locus_tag="Smed_3726"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.785) with cleavage site probability 0.599 at
                     residue 33"
     misc_feature    complement(<169478..169732)
                     /locus_tag="Smed_3726"
                     /note="Cellulose synthase-like protein; Region: PLN02893"
                     /db_xref="CDD:215483"
     misc_feature    complement(168908..169603)
                     /locus_tag="Smed_3726"
                     /note="CESA_CelA_like are involved in the elongation of
                     the glucan chain of cellulose; Region: CESA_CelA_like;
                     cd06421"
                     /db_xref="CDD:133043"
     misc_feature    complement(168932..169603)
                     /locus_tag="Smed_3726"
                     /note="Glycosyltransferase like family 2; Region:
                     Glyco_tranf_2_3; pfam13641"
                     /db_xref="CDD:222281"
     misc_feature    complement(169334..169342)
                     /locus_tag="Smed_3726"
                     /note="DXD motif; other site"
                     /db_xref="CDD:133043"
     gene            complement(169930..171162)
                     /locus_tag="Smed_3727"
                     /db_xref="GeneID:5318593"
     CDS             complement(169930..171162)
                     /locus_tag="Smed_3727"
                     /note="KEGG: sme:SMb20390 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312473.1"
                     /db_xref="GI:150375877"
                     /db_xref="GeneID:5318593"
                     /translation="MILNHRLTRITVGILLLALAIAVLLPGLTGYSSLDGTVNARFAV
                     INAPVDGEIDKAPPRIGTPVKEGETLATISNERVNRAVLASLRTDHRTALERVAALRR
                     ERDELVRLRDDLAGRLDIFRNATIASLERELQILQKRVEVSRAQEVVARVDLDRRQDL
                     ESKGIFTRKMVESAEAAGAAAGGELEISNLTVELLQERLSAVRKGIFIVGDGQNDVPY
                     SRQRQDEVIVRIHDLNTRIAENETRAKQTDQQIAEEERRVLNLESATIPSPLDGVVWT
                     RNVVSGSNVVLNSEVMRILDCRDLFVDILVPEVDYDEIYPGRDAEVRLFGRGDVFKGR
                     VQAVKGSSAVVEKDSLAANEPEADERNARIRVTLAPSALNADFANFCQVGRTAQVRFS
                     KRSLHVAQWIQSLWFNLF"
     sig_peptide     complement(171058..171162)
                     /locus_tag="Smed_3727"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.982) with cleavage site probability 0.417 at
                     residue 35"
     misc_feature    complement(170128..>170793)
                     /locus_tag="Smed_3727"
                     /note="efflux pump membrane protein (multidrug resistance
                     protein A); Region: 8a0101; TIGR00998"
                     /db_xref="CDD:233228"
     gene            171511..172536
                     /locus_tag="Smed_3728"
                     /db_xref="GeneID:5318594"
     CDS             171511..172536
                     /locus_tag="Smed_3728"
                     /note="TIGRFAM: diguanylate cyclase;
                     PFAM: GGDEF domain containing protein; GAF domain protein;
                     KEGG: sme:SMb20389 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="YP_001312474.1"
                     /db_xref="GI:150375878"
                     /db_xref="InterPro:IPR000160"
                     /db_xref="InterPro:IPR003018"
                     /db_xref="GeneID:5318594"
                     /translation="MGQALRILTNERQRLLAVRSLNSVESAPTPELATLAELAKGVFG
                     VSYAAINIIDEDWQRIAGQAGLRIGECSREMSICTRVVFEDELLVIPDLTEDQDLRSR
                     PYVVGSPHFRFYAGAPVYLDNLPVGSFCILDGRPGNLSDGQALNLRRFAEVASALLSL
                     QKANLVMGLAHNQLQNAAITDPLTGLFNRSALSSIVDGALDNAMTAGQTFGALYLDMD
                     GFKAINDKLGHQVGDAVLYEAANRIRSVIRAGDIPVRMGGDEFAVFVPNPPNAPALAA
                     VSQRLVSVFREPVEVDGEAIQARISIGGALAPDNGRRRADLLNSCDKALYAAKRGGRD
                     RFVVVGA"
     misc_feature    171604..171993
                     /locus_tag="Smed_3728"
                     /note="GAF domain; Region: GAF; pfam01590"
                     /db_xref="CDD:216590"
     misc_feature    171604..171981
                     /locus_tag="Smed_3728"
                     /note="FOG: GAF domain [Signal transduction mechanisms];
                     Region: FhlA; COG2203"
                     /db_xref="CDD:225113"
     misc_feature    172018..172524
                     /locus_tag="Smed_3728"
                     /note="c-di-GMP synthetase (diguanylate cyclase, GGDEF
                     domain) [Signal    transduction mechanisms]; Region:
                     COG2199"
                     /db_xref="CDD:225109"
     misc_feature    172048..172521
                     /locus_tag="Smed_3728"
                     /note="Diguanylate-cyclase (DGC) or GGDEF domain; Region:
                     GGDEF; cd01949"
                     /db_xref="CDD:143635"
     misc_feature    order(172156..172158,172285..172287)
                     /locus_tag="Smed_3728"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143635"
     misc_feature    order(172171..172173,172180..172185,172195..172197,
                     172207..172209,172273..172275,172279..172290)
                     /locus_tag="Smed_3728"
                     /note="active site"
                     /db_xref="CDD:143635"
     misc_feature    order(172261..172263,172348..172350)
                     /locus_tag="Smed_3728"
                     /note="I-site; other site"
                     /db_xref="CDD:143635"
     gene            172560..173549
                     /locus_tag="Smed_3729"
                     /db_xref="GeneID:5318595"
     CDS             172560..173549
                     /locus_tag="Smed_3729"
                     /note="PFAM: Alcohol dehydrogenase zinc-binding domain
                     protein; Alcohol dehydrogenase GroES domain protein;
                     KEGG: sme:SMb20388 putative NADPH:quinone oxidoreductase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="YP_001312475.1"
                     /db_xref="GI:150375879"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="GeneID:5318595"
                     /translation="MRAAWYEKNGAAREVLKVGSLPEPLPGPGEVRVRIHASGVNPSD
                     VKARAGRPVIAPQMIPHSDGAGIIDAVGAEVAGERIGERVWTWNAAWRRSNGTAAEYV
                     VLPQDQAVHLPDNVSFEEGACLGIPALTALRAVTMDGSVFGRTVLVAGGAGSVGAYAI
                     QFARLYGAARIVTTVSSAQKAEICLRLGADDTINYKTEDVVDRIKDITNGRGVDRVIE
                     VDAATNAKMLPEIIAQDGLLVIYGSSKPDISFEFLPMILAGIAARFFIVYEMSPEVRA
                     ETVSALHSQLRSGLLRHHIAEIYALDDIAAAHEAVESGKTVGNVVVSLSPTPS"
     misc_feature    172560..173531
                     /locus_tag="Smed_3729"
                     /note="Zeta-crystallin with NADP-dependent quinone
                     reductase activity (QOR); Region: zeta_crystallin;
                     cd08253"
                     /db_xref="CDD:176215"
     misc_feature    172560..173525
                     /locus_tag="Smed_3729"
                     /note="NADPH:quinone reductase and related Zn-dependent
                     oxidoreductases [Energy production and conversion /
                     General function prediction only]; Region: Qor; COG0604"
                     /db_xref="CDD:223677"
     misc_feature    order(172683..172685,172695..172697,172935..172937,
                     172947..172949,173004..173024,173082..173087,
                     173142..173147,173214..173219,173229..173231,
                     173280..173285,173298..173300,173352..173360,
                     173490..173492,173502..173507)
                     /locus_tag="Smed_3729"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:176215"
     gene            173839..174558
                     /locus_tag="Smed_3730"
                     /db_xref="GeneID:5318596"
     CDS             173839..174558
                     /locus_tag="Smed_3730"
                     /note="PFAM: regulatory protein IclR; Transcriptional
                     regulator IclR;
                     KEGG: sme:SMb20387 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein IclR"
                     /protein_id="YP_001312476.1"
                     /db_xref="GI:150375880"
                     /db_xref="InterPro:IPR005471"
                     /db_xref="InterPro:IPR014757"
                     /db_xref="GeneID:5318596"
                     /translation="MSVRPLSSVLKTLATFECIGAAAEPLRLADVARQLGEARGAVHQ
                     RLVTLVEAGWIEQTTDGRYRLTLRIVGHAAMALEQSNLGARFAGVLEEMVTQSGETAS
                     LAILDGKSAVIVRRVESRGILRADLRIGTQLRLDRTAFGRVLVSFARSEIVDRLRAEG
                     VELPGDEIIAEVRKCGYAISEVEGPRTVSAVAAPIIDAQGECIGALALSGPFTGFDTD
                     KCARIVVAAAAASAARLRGEQ"
     misc_feature    173857..174510
                     /locus_tag="Smed_3730"
                     /note="Transcriptional regulator [Transcription]; Region:
                     IclR; COG1414"
                     /db_xref="CDD:224332"
     misc_feature    173860..174114
                     /locus_tag="Smed_3730"
                     /note="IclR helix-turn-helix domain; Region: HTH_IclR;
                     cl17605"
                     /db_xref="CDD:248159"
     misc_feature    174202..>174471
                     /locus_tag="Smed_3730"
                     /note="Bacterial transcriptional regulator; Region: IclR;
                     pfam01614"
                     /db_xref="CDD:201890"
     gene            174560..176296
                     /locus_tag="Smed_3731"
                     /db_xref="GeneID:5318597"
     CDS             174560..176296
                     /locus_tag="Smed_3731"
                     /note="KEGG: sme:SMb20386 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312477.1"
                     /db_xref="GI:150375881"
                     /db_xref="GeneID:5318597"
                     /translation="MSALTKTVPESAAHRIARLMRSPADIMKPERLAAIQPSRVSASR
                     ALMSRAVRQRWQILCKRFDIDAKGNGVAEYRIDIGGWRFSFPVYSFEPSPHGRTGRII
                     GRAWDMMGALVEGDMSRRDFETTRTELPKLYEGRATPGTLIWCRSNRSGRFFEGAKAA
                     LQAGGQPNVAELAHTCYLMRNTGLDGNGTFGTKSFLAYEGDHPLRWSLAAQMLCAYMM
                     RVFAQDLLAHLVRLEAPAAPRMAIELRRFLGVGNGSALGLMLFVNNHPRLIERWLFIR
                     EEAIARAKGLTPDENGSEIAKLLSLVDKAITFRSEDRVQYENVTRSDVVARELGIIRS
                     AVAKLLDRWRSGSRFESEPFAELTASLECRVHAEAMETLHSLLIELVAEEADQLVEGL
                     VIDEELTGRPEMPVARLREILRNDYAWAFGLDLDIGSEKRYVWYKSVSAEEPRRGPVA
                     EVGENVVNLGLDLPRLVVSLDRDLAAADPTLSTARFLLARPEHRAIATRVQALAGTGL
                     HSPHADIMSEHFTPAHITRLLNVGIHGIDKTRDFLDRNLRGVLFHGAPVPEDIAAGSA
                     DDLWFYPSEPSL"
     gene            176293..177021
                     /locus_tag="Smed_3732"
                     /db_xref="GeneID:5318660"
     CDS             176293..177021
                     /locus_tag="Smed_3732"
                     /note="KEGG: sme:SMb20385 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312478.1"
                     /db_xref="GI:150375882"
                     /db_xref="GeneID:5318660"
                     /translation="MSSCQSNLPSTLTVSLREMRMVFERLVQVARVDAGLVPSLRDCA
                     LYSAALGLGGFARLLHNLEAVRSANPHVLSLTADGERLIVDCGGQHAWIAADAVLDLA
                     TERLRTQGAGTITVRTATEVDELRVVEALAQRFGLNAEVAIDGTTGCAEIVVSPAAKE
                     MHPTVLERIRRDGLTVDAALWWQLFHQSAEALAPDSYVSRRHAGPIIVEADGKVIGRQ
                     DEDETDLSLLIAGAEKHGTTAINN"
     gene            177034..178005
                     /locus_tag="Smed_3733"
                     /db_xref="GeneID:5318661"
     CDS             177034..178005
                     /locus_tag="Smed_3733"
                     /EC_number="3.4.13.19"
                     /note="PFAM: peptidase M19 renal dipeptidase;
                     KEGG: sme:SMb20384 putative dipeptidase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="YP_001312479.1"
                     /db_xref="GI:150375883"
                     /db_xref="InterPro:IPR008257"
                     /db_xref="GeneID:5318661"
                     /translation="MIIDALQCGHFDRGSFEALRRGGYSAVTPTLGFWEGTMESLDSL
                     ARWRDMERENADLILIARTAADIERAETEGKLAVVLGYQNSNLFEDRIAFVEFFAELG
                     VRVVQLTYNNQNELGGSCYEENDSGLARFGRDVVREMNRVGMLVDLSHVGDRTTLDAI
                     EWSERPVAITHANAASLFAHKRNKSDKVIKALAERGGVIGCVAYRNITPDAACATVDG
                     WCEMVARTVDIAGIDHVGIGTDISHNHTPRDYDWMRKGRWTRSVQYGAGSPERPGAVA
                     KPEWLLKPENLQDVAAALLRAGFNQEEANKILRGNWLRLYAEVFRPN"
     misc_feature    177034..177999
                     /locus_tag="Smed_3733"
                     /note="Zn-dependent dipeptidase, microsomal dipeptidase
                     homolog [Amino acid transport and metabolism]; Region:
                     COG2355"
                     /db_xref="CDD:225230"
     misc_feature    177064..177987
                     /locus_tag="Smed_3733"
                     /note="Membrane dipeptidase (Peptidase family M19);
                     Region: Peptidase_M19; pfam01244"
                     /db_xref="CDD:216386"
     misc_feature    order(177478..177480,177544..177546,177778..177780)
                     /locus_tag="Smed_3733"
                     /note="active site"
                     /db_xref="CDD:238617"
     gene            178111..179184
                     /locus_tag="Smed_3734"
                     /db_xref="GeneID:5318662"
     CDS             178111..179184
                     /locus_tag="Smed_3734"
                     /note="KEGG: sme:SMb20383 putative ABC transporter
                     periplasmic solute-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter periplasmic
                     solute-binding protein"
                     /protein_id="YP_001312480.1"
                     /db_xref="GI:150375884"
                     /db_xref="GeneID:5318662"
                     /translation="MEMFKNASATPLSRRAVLGAGLFGAAMLASPSIRRASAEENALY
                     VNTWGGDWEASVKKFLFEPFTADTGIEIRTVSPISFAKLAAQKTTGVYEFDVTTLGVA
                     DVARANGAGLLETLEGHVDTSKLWEGAIYENGLATHGFATQMAYNAAKFPEGLKNWSD
                     FFNVEKFPGNRSLQRHAARVLAIALLADGVPADQLFPYDLDRAFASLDRIKDHVRVWW
                     TAGPQARQILTDGEVDMAGLWDSDAFGAKEASKEPIEIVWDQAVVDKACWIVAKDSPR
                     AENGFKLISHIGQNAEGLAKFCIADQNGPMNPKSFDFIPAEVAARMPTHPEHLARAVM
                     LDGAKLLPQLHELSTRFESWVGI"
     sig_peptide     178111..178227
                     /locus_tag="Smed_3734"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.994) with cleavage site probability 0.891 at
                     residue 39"
     misc_feature    178198..179175
                     /locus_tag="Smed_3734"
                     /note="Spermidine/putrescine-binding periplasmic protein
                     [Amino acid transport and metabolism]; Region: PotD;
                     COG0687"
                     /db_xref="CDD:223759"
     gene            179310..180161
                     /locus_tag="Smed_3735"
                     /db_xref="GeneID:5318663"
     CDS             179310..180161
                     /locus_tag="Smed_3735"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20382 putative ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312481.1"
                     /db_xref="GI:150375885"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318663"
                     /translation="MKLRTSPVFVEGPMPLIAPAVMFLSLFFLVPLGYVVWMSLSQPV
                     IGLQNFGRLLNSSLFASVLYSTFKTALLVTLLSLLFAYPLAYAAANGSKRFATFLLTV
                     VALSFWTSYLVRTYAWMVILGNQGPVTALLSWLGWDPAPKILFTTFSATLAMTHALIP
                     FMTMSLFAVMKRIDPLYVRAAENLGAHPLRAFVSVYLPLSAPGIVNGCTLVFITCLGF
                     YVMPVLLGSPRDQMIAGIIGDQIEQTLDFGLGSAISIVLLALTLAVYAVYNRFFGLDR
                     LWAGGDR"
     misc_feature    179355..>179915
                     /locus_tag="Smed_3735"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cl00427"
                     /db_xref="CDD:241857"
     misc_feature    <179697..180074
                     /locus_tag="Smed_3735"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(179697..179699,179703..179705,179778..179783,
                     179790..179792,179799..179804,179808..179810,
                     179820..179825,179832..179834,179883..179885,
                     179925..179930,179937..179939,179958..179969,
                     179976..179981,180018..180023,180051..180056,
                     180063..180068,180072..180074)
                     /locus_tag="Smed_3735"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(179703..179705,179763..179765,179976..179978,
                     180012..180014,180021..180023,180051..180053)
                     /locus_tag="Smed_3735"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(179835..179873,179889..179894,179904..179906)
                     /locus_tag="Smed_3735"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            180158..180988
                     /locus_tag="Smed_3736"
                     /db_xref="GeneID:5318664"
     CDS             180158..180988
                     /locus_tag="Smed_3736"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20381 putative ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001312482.1"
                     /db_xref="GI:150375886"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318664"
                     /translation="MNVWIRSLAILIAAFVAAPMFIVIPMSFSSAASLAFPPPGYTLQ
                     NYVNFFSDPNWTQPLTNSLLIGLGTVCMTMLVAVPASFALVRHVFIGRTVFNLLIMLP
                     MIVPTIVMAIGYYIYFGQLRLVQSYLGVILAHSCIALPMSTLILTAALKGFDRSVERA
                     AMNLGASPFTTFRLITFPILRPAFTVAGLFAFIASFDEAVIGLFISGRDKATLPRQMF
                     NAVRQEADPTISAASSFLFLLVLAGVCIWLAPQLVRRRTRLLGQTDGNGAAQPAAATS
                     "
     sig_peptide     180158..180265
                     /locus_tag="Smed_3736"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.830 at
                     residue 36"
     misc_feature    180167..180931
                     /locus_tag="Smed_3736"
                     /note="ABC-type spermidine/putrescine transport system,
                     permease component II [Amino acid transport and
                     metabolism]; Region: PotC; COG1177"
                     /db_xref="CDD:224098"
     misc_feature    180332..180799
                     /locus_tag="Smed_3736"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(180380..180385,180392..180397,180410..180412,
                     180440..180451,180455..180484,180491..180496,
                     180500..180502,180560..180562,180566..180568,
                     180572..180574,180578..180580,180587..180592,
                     180596..180598,180608..180613,180620..180622,
                     180671..180673,180713..180718,180725..180727,
                     180746..180757,180764..180769)
                     /locus_tag="Smed_3736"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(180458..180502,180746..180763)
                     /locus_tag="Smed_3736"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(180500..180502,180545..180547,180764..180766)
                     /locus_tag="Smed_3736"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(180623..180661,180677..180682,180692..180694)
                     /locus_tag="Smed_3736"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            181004..182053
                     /locus_tag="Smed_3737"
                     /db_xref="GeneID:5318665"
     CDS             181004..182053
                     /locus_tag="Smed_3737"
                     /note="PFAM: ABC transporter related; Transport-associated
                     OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20380 putative ABC transporter ATP-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312483.1"
                     /db_xref="GI:150375887"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5318665"
                     /translation="MNARSLTLSNITKTYDGRHMAADDVSLDIKAGEFVSFLGPSGSG
                     KTTTLMMIAGFQHPTSGEIRLGERAIDNLPPHKRNIGMVFQNYALFPHMTVADNVGFP
                     LRMRGVAKQDKERRSREALAKVGLQGFEKRVPSELSGGQQQRVALARALVFEPDIILL
                     DEPLGALDKALREHMQVELKRIHKDLGVTMVYVTHDQSEAMTMSDRIAVFNQGRLEQV
                     GTPNEIYRAPKTRFVACFIGDSNLIEGSALGGGRFDTPVGIVEARSSQTDRNRRADLL
                     LRPEMIRIAETSQGGRQPLKIDSTINYGDNLLVIGKLGSQAIRMRVPGADARRLEGVS
                     ECHVTWRAEDVHVIA"
     misc_feature    181004..182050
                     /locus_tag="Smed_3737"
                     /note="ABC-type spermidine/putrescine transport systems,
                     ATPase components [Amino acid transport and metabolism];
                     Region: PotA; COG3842"
                     /db_xref="CDD:226361"
     misc_feature    181019..181717
                     /locus_tag="Smed_3737"
                     /note="ATP-binding cassette domain of the polyamine
                     transporter; Region: ABC_PotA_N; cd03300"
                     /db_xref="CDD:213267"
     misc_feature    181118..181141
                     /locus_tag="Smed_3737"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213267"
     misc_feature    order(181127..181132,181136..181144,181256..181258,
                     181484..181489,181586..181588)
                     /locus_tag="Smed_3737"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213267"
     misc_feature    181247..181258
                     /locus_tag="Smed_3737"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213267"
     misc_feature    181412..181441
                     /locus_tag="Smed_3737"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213267"
     misc_feature    181472..181489
                     /locus_tag="Smed_3737"
                     /note="Walker B; other site"
                     /db_xref="CDD:213267"
     misc_feature    181496..181507
                     /locus_tag="Smed_3737"
                     /note="D-loop; other site"
                     /db_xref="CDD:213267"
     misc_feature    181574..181594
                     /locus_tag="Smed_3737"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213267"
     misc_feature    181826..182047
                     /locus_tag="Smed_3737"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            182084..183469
                     /locus_tag="Smed_3738"
                     /db_xref="GeneID:5318666"
     CDS             182084..183469
                     /locus_tag="Smed_3738"
                     /note="PFAM: aminotransferase class-III;
                     KEGG: sme:SMb20379 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="YP_001312484.1"
                     /db_xref="GI:150375888"
                     /db_xref="InterPro:IPR005814"
                     /db_xref="GeneID:5318666"
                     /translation="MNDRPNSLHALDKQSLVHPYTNLAVHQETGPHVITGGDGIYVVD
                     DEGKRYIEGLAGLFCAGLGFSEQRLVEAAMRQLKTMPFYHSFAHKSTEPGIRLAEKLL
                     SIAPVPMSKVFFAGSGSEANDTAIKLIWYYNNALGRPDKKKIISRRKAYHGVTVATAS
                     LTGLPFNHRDFDLPIANILHTDCPHYWRSAETGETEEDFATRMADNLEATILEEGPET
                     IAAFFAEPVMVSGGVITPPKTYFEKVQAVLRKYDILLVADEVICGFGRTGNMFGSETY
                     GLKPDMISCAKQLSAAYMPISALMINQKIADALVDQSRKIGTFSHGFTYGGHPVAAAV
                     ALQALTIYEEIDIVGHVRSVAPVFQDRARKLGEHPLIGEARGVGLVAGFEFVKDKATR
                     ENFPPAWQVANQAGKFATARGVLTRGLGDMVSLCPAMIIDEGQIDDLMTRMGLALDDT
                     LAWARTQGHVA"
     misc_feature    182084..183463
                     /locus_tag="Smed_3738"
                     /note="aminotransferase; Provisional; Region: PRK06105"
                     /db_xref="CDD:180401"
     misc_feature    182105..183424
                     /locus_tag="Smed_3738"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     Region: OAT_like; cd00610"
                     /db_xref="CDD:99735"
     misc_feature    order(182432..182440,182534..182539,182543..182545,
                     182756..182758,182855..182857,182861..182866,
                     182942..182944)
                     /locus_tag="Smed_3738"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99735"
     misc_feature    order(182435..182440,182534..182539,182756..182758,
                     182855..182857,182864..182866,182942..182944)
                     /locus_tag="Smed_3738"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99735"
     misc_feature    182942..182944
                     /locus_tag="Smed_3738"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     gene            183480..184943
                     /locus_tag="Smed_3739"
                     /db_xref="GeneID:5318667"
     CDS             183480..184943
                     /locus_tag="Smed_3739"
                     /note="PFAM: aldehyde dehydrogenase;
                     KEGG: sme:SMb20378 putative aldehyde dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="YP_001312485.1"
                     /db_xref="GI:150375889"
                     /db_xref="InterPro:IPR002086"
                     /db_xref="GeneID:5318667"
                     /translation="MNPESTAPAYGRLGMLIDGRWVYEAEGSSDVVNPATGQTIARLP
                     HASDSEIAEAVASSQRAFESWKDRSPLERSHILRRFADLARKHAEEIAANMTLDQGKP
                     LGEAIGEVRFAADHADWHAEEARRTYGRIIPSRDPRVQQMVVREPVGVCVAFTPWNFP
                     FSQALRKVVAALASGCTIILKGPGESPSSTVAIGRLMQEAGLPDGCLNIVWGDPAHLS
                     ESLLGAPEVRKLSFTGSVGVGKHLASLAGKYMKRSTMELGGHAPVIVFDDADIEAAAD
                     ALAGQKVRNAGQVCISPTRFYVQAKEHDRFLARFTERIASTKVGDGFQEGVQMGPLCH
                     SRRLAAMEDFVQDAREQGATIVTGGERIGNAGFFYAPTVVAGGTDELRLMKAEPFGPI
                     AVVTPFGNFDEVIRRANSLPFGLASYVFTASSNRAQHAAQALAAGMVSINHFGLALPE
                     TPFGGINDSGYGSEGGSETLDGYLNTKFVTRFDQIPQ"
     misc_feature    183540..184916
                     /locus_tag="Smed_3739"
                     /note="Aldehyde dehydrogenase family; Region: Aldedh;
                     pfam00171"
                     /db_xref="CDD:215767"
     misc_feature    183570..184919
                     /locus_tag="Smed_3739"
                     /note="Mitochondrial succinate-semialdehyde dehydrogenase
                     and ALDH family members 5A1 and 5F1-like; Region:
                     ALDH_F5_SSADH_GabD; cd07103"
                     /db_xref="CDD:143421"
     misc_feature    order(183684..183686,183711..183713,183834..183836,
                     183843..183848,183852..183878,183894..183902,
                     183915..183917,184161..184163,184197..184199,
                     184209..184211,184218..184220,184389..184391,
                     184401..184403,184539..184541,184743..184745,
                     184749..184754,184764..184766,184770..184772,
                     184779..184781,184785..184805,184821..184823,
                     184830..184835,184851..184853,184866..184868,
                     184902..184919)
                     /locus_tag="Smed_3739"
                     /note="tetramerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:143421"
     misc_feature    order(183939..183953,183975..183977,184020..184022,
                     184026..184031,184173..184184,184191..184193,
                     184200..184205,184245..184253,184347..184349,
                     184638..184640,184644..184646,184722..184724,
                     184836..184838)
                     /locus_tag="Smed_3739"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:143421"
     misc_feature    order(183951..183953,184245..184247,184338..184340,
                     184347..184349)
                     /locus_tag="Smed_3739"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143421"
     gene            184977..185360
                     /locus_tag="Smed_3740"
                     /db_xref="GeneID:5318668"
     CDS             184977..185360
                     /locus_tag="Smed_3740"
                     /note="PFAM: Endoribonuclease L-PSP;
                     KEGG: sme:SMb20377 putative translation initiation
                     inhibitor protein"
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease L-PSP"
                     /protein_id="YP_001312486.1"
                     /db_xref="GI:150375890"
                     /db_xref="InterPro:IPR006175"
                     /db_xref="GeneID:5318668"
                     /translation="MFEVIDTGADPSDVPVSEAVRAGGLFWSVHVSEDPVTGEPVFGD
                     IETQARRTLQNLEIAIRAAGGSLANVVQMQVFLTERADAPGMNRTYTEFFREPYPVRA
                     TVVVKELITPGLRIEVLAHAVLDSA"
     misc_feature    185025..185342
                     /locus_tag="Smed_3740"
                     /note="YjgF, YER057c, and UK114 belong to a large family
                     of proteins present in bacteria, archaea, and eukaryotes
                     with no definitive function. The conserved domain is
                     similar in structure to chorismate mutase but there is no
                     sequence similarity and no...; Region:
                     YjgF_YER057c_UK114_family; cd00448"
                     /db_xref="CDD:100004"
     misc_feature    order(185025..185027,185034..185036,185040..185042,
                     185052..185054,185058..185063,185181..185183,
                     185187..185192,185196..185198,185202..185204,
                     185235..185237,185244..185246,185271..185294,
                     185325..185327,185331..185333,185337..185339)
                     /locus_tag="Smed_3740"
                     /note="homotrimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:100004"
     misc_feature    order(185223..185225,185235..185237,185277..185279,
                     185325..185327)
                     /locus_tag="Smed_3740"
                     /note="putative active site [active]"
                     /db_xref="CDD:100004"
     gene            185404..185784
                     /locus_tag="Smed_3741"
                     /db_xref="GeneID:5318731"
     CDS             185404..185784
                     /locus_tag="Smed_3741"
                     /note="PFAM: Endoribonuclease L-PSP;
                     KEGG: sme:SMb20376 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease L-PSP"
                     /protein_id="YP_001312487.1"
                     /db_xref="GI:150375891"
                     /db_xref="InterPro:IPR006175"
                     /db_xref="GeneID:5318731"
                     /translation="MFEKVETGITASRAPLSGTVKAGQIVRSVHIAKNPETGELVTGD
                     IECQARQVFSNLRQALEAAGSTLAAVAQIQAYLIDRADAAGMNKVYREFFTPPYPVRA
                     TVVTELLSPGIRLEILATAVCSRD"
     misc_feature    185452..185766
                     /locus_tag="Smed_3741"
                     /note="YjgF, YER057c, and UK114 belong to a large family
                     of proteins present in bacteria, archaea, and eukaryotes
                     with no definitive function. The conserved domain is
                     similar in structure to chorismate mutase but there is no
                     sequence similarity and no...; Region:
                     YjgF_YER057c_UK114_family; cd00448"
                     /db_xref="CDD:100004"
     misc_feature    order(185452..185454,185461..185463,185467..185469,
                     185476..185478,185482..185484,185485..185490,
                     185608..185610,185614..185619,185623..185625,
                     185629..185631,185662..185664,185671..185673,
                     185698..185721,185749..185751,185755..185757,
                     185761..185763)
                     /locus_tag="Smed_3741"
                     /note="homotrimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:100004"
     misc_feature    order(185650..185652,185662..185664,185704..185706,
                     185749..185751)
                     /locus_tag="Smed_3741"
                     /note="putative active site [active]"
                     /db_xref="CDD:100004"
     gene            186060..186869
                     /locus_tag="Smed_3742"
                     /db_xref="GeneID:5318732"
     CDS             186060..186869
                     /locus_tag="Smed_3742"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20375 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR domain-containing protein"
                     /protein_id="YP_001312488.1"
                     /db_xref="GI:150375892"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318732"
                     /translation="MWCLLVLPVGTICMNPVLSDSADELAGTEKVLSFFREQLLSGAL
                     KVGDRLLGERELCLALGVSRPVLREALRSLANLGFLDIRHGKGAFVRKADVGVFGDFL
                     TFCLAQQPDMLDDIMQARVAIECQAIRLACIRATDSDLSRIGSLLTRLMETLHDAEDG
                     GAADFAFHMAIVEASRSPALTTVYRSISDLLKRSHVQRRAETSDAPGITDYLVEAHRE
                     VFLSILARDPDKADRMLREHFAIGDELRRKSYIAAFTRKDAPQEEEKEADS"
     sig_peptide     186060..186119
                     /locus_tag="Smed_3742"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.682) with cleavage site probability 0.636 at
                     residue 20"
     misc_feature    186141..186827
                     /locus_tag="Smed_3742"
                     /note="Transcriptional regulators [Transcription]; Region:
                     FadR; COG2186"
                     /db_xref="CDD:225097"
     misc_feature    186165..186332
                     /locus_tag="Smed_3742"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    order(186210..186212,186216..186221,186243..186257,
                     186261..186266,186273..186275,186303..186308,
                     186312..186323)
                     /locus_tag="Smed_3742"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    186402..186779
                     /locus_tag="Smed_3742"
                     /note="This entry represents the C-terminal ligand binding
                     domain of many members of the GntR family; Region: FCD;
                     smart00895"
                     /db_xref="CDD:214892"
     gene            186893..187885
                     /locus_tag="Smed_3743"
                     /db_xref="GeneID:5318733"
     CDS             186893..187885
                     /locus_tag="Smed_3743"
                     /note="TIGRFAM: TRAP dicarboxylate transporter, DctP
                     subunit;
                     PFAM: TRAP dicarboxylate transporter- DctP subunit;
                     KEGG: sme:SMb20374 putative periplasmic substrate-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctP"
                     /protein_id="YP_001312489.1"
                     /db_xref="GI:150375893"
                     /db_xref="InterPro:IPR004682"
                     /db_xref="GeneID:5318733"
                     /translation="MLNFLKHGRITGAMLGAALLTGAASATELRYAHVGAEGDIQTVY
                     AAQAAEGIAAATGGEVTVTVYPASQLGGVAEMVDGVRMGSISMGHHDFASLARLVPEV
                     AVFNAPFIYRDGAHALAATDPQTSPALQAINEKLVAQGVRIIGRIYRGDRHISSNFPV
                     KTPADLAGKPFRAVPLELWVSMVKGFGAIPTPVEVAELPTALMTGVVVGQENPLTMIA
                     SNNLNEVQSHLSMTGHMRAVLAVFINEDVWQGLSEEQRSALTKVLDEEARKSLKMATE
                     SEADLVKELKGRGMTVITEAEGLDVAAFREKVSAQIRQDFPDFAPLIEQIEAVK"
     sig_peptide     186893..186973
                     /locus_tag="Smed_3743"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.988 at
                     residue 27"
     misc_feature    186977..187882
                     /locus_tag="Smed_3743"
                     /note="TRAP-type C4-dicarboxylate transport system,
                     periplasmic component [Carbohydrate transport and
                     metabolism]; Region: DctP; COG1638"
                     /db_xref="CDD:224553"
     misc_feature    186983..187834
                     /locus_tag="Smed_3743"
                     /note="Bacterial extracellular solute-binding protein,
                     family 7; Region: SBP_bac_7; cl15441"
                     /db_xref="CDD:210106"
     gene            187964..188431
                     /locus_tag="Smed_3744"
                     /db_xref="GeneID:5318734"
     CDS             187964..188431
                     /locus_tag="Smed_3744"
                     /note="PFAM: Tripartite ATP-independent periplasmic
                     transporter DctQ component;
                     KEGG: sme:SMb20373 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite ATP-independent periplasmic
                     transporter DctQ"
                     /protein_id="YP_001312490.1"
                     /db_xref="GI:150375894"
                     /db_xref="InterPro:IPR007387"
                     /db_xref="GeneID:5318734"
                     /translation="MRLPERVLTIVVVTVMSGLIIVPTAQVIMRGVFRLPFIGAEELT
                     RFLLICLVFLSYPLVVGHGENIVMGELKAAMPKKARAIVNVAISVVAIAVTGFIGWVT
                     ASNITRNLANATPTLGIPFWIFLGATLFGFAAAALIHLLHLRKPPQADKNVAV"
     misc_feature    187964..>188332
                     /locus_tag="Smed_3744"
                     /note="TRAP-type C4-dicarboxylate transport system, small
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctM; COG3090"
                     /db_xref="CDD:225632"
     gene            188444..189721
                     /locus_tag="Smed_3745"
                     /db_xref="GeneID:5318735"
     CDS             188444..189721
                     /locus_tag="Smed_3745"
                     /note="TIGRFAM: TRAP dicarboxylate transporter, DctM
                     subunit;
                     PFAM: TRAP C4-dicarboxylate transport system permease DctM
                     subunit;
                     KEGG: sme:SMb20372 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctM"
                     /protein_id="YP_001312491.1"
                     /db_xref="GI:150375895"
                     /db_xref="InterPro:IPR004681"
                     /db_xref="InterPro:IPR010656"
                     /db_xref="GeneID:5318735"
                     /translation="MGFLVVLAFLGLFMIGFPVVYAILLPSILYVLVEGLPFGLLAQR
                     ITYALDSFPLVAVPLFIFVGNLMNLSGITDRIFRFAYTLVGRVPGGLAQVNVFGSLIF
                     SGMSGAALADIGGLGRIEIDAMKKRGFDPSFAGAVTAASATLGPIFPPSIPLIVYGSV
                     TSVSIVQLLVAGIMPAVLCTALLMLTVLIVAIRHGHARAERWPTAGELVASLVPALPA
                     ILAPVLMVGGMTAGAFTPTEAAAITAVYVIFISAALYRELTPAHLWHSAVLTARSSSA
                     ILIIVASAALFGWILAVEQVPQTFAATLLGWSKDPLMLLIIANLIFFIAGMFLDSTTA
                     TLLLVPIIAPPLVMAGVDPVQLGIVTIFNLMLGLLTPPMGLSLFLVSDIAQVSIRQLL
                     RALVPFYIPLVSTLVILTLAKDLTLWLPRLIAQ"
     sig_peptide     188444..188512
                     /locus_tag="Smed_3745"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.802) with cleavage site probability 0.783 at
                     residue 23"
     misc_feature    188486..189676
                     /locus_tag="Smed_3745"
                     /note="DctM-like transporters; Region: DctM; pfam06808"
                     /db_xref="CDD:219185"
     misc_feature    188576..189712
                     /locus_tag="Smed_3745"
                     /note="TRAP-type C4-dicarboxylate transport system, large
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctQ; COG1593"
                     /db_xref="CDD:224509"
     gene            189745..190191
                     /locus_tag="Smed_3746"
                     /db_xref="GeneID:5318736"
     CDS             189745..190191
                     /locus_tag="Smed_3746"
                     /EC_number="5.3.1.6"
                     /note="catalyzes the interconversion of ribose 5-phosphate
                     to ribulose 5-phosphate; enzyme from E. coli shows allose
                     6-phosphate isomerase activity"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase B"
                     /protein_id="YP_001312492.1"
                     /db_xref="GI:150375896"
                     /db_xref="InterPro:IPR003500"
                     /db_xref="InterPro:IPR004785"
                     /db_xref="GeneID:5318736"
                     /translation="MRIVIGSDHAGFPLKATIIDHIVSLGHEVHDAGSYDPSPVDFPD
                     IAKTVTSSIIDGKADRGLMVCGTGVGASIAANKVKGIRAAVCHDVHSAHQSVEHDDVN
                     VMCIGAQIVGAWLAKDLVAAYLAAEFSTDEDFRRRVRKLAEMDEQR"
     misc_feature    189745..190188
                     /locus_tag="Smed_3746"
                     /note="ribose-5-phosphate isomerase B; Provisional;
                     Region: PRK05571"
                     /db_xref="CDD:235509"
     gene            complement(190227..190907)
                     /locus_tag="Smed_3747"
                     /db_xref="GeneID:5318737"
     CDS             complement(190227..190907)
                     /locus_tag="Smed_3747"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20370 putative ATP-binding transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312493.1"
                     /db_xref="GI:150375897"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318737"
                     /translation="MSPLIEAHGLTRILQETVPVTLVKDIDLTIGEGEFVAVTGLSGS
                     GKSSLLYLLGLLDRPTRGMLRVRGRDTEPMSETSRAETRLSTMGFVFQFHFLLPEFTA
                     RENVEIPMRKVARLGRDEMRARATELLSSLGLVDHLDKRPDQLSGGQRQRVAVARALA
                     NDPPLILADEPTGSLDSTSSEQVFAILDGLVRERGKTVVAVTHDFGMAARMDRRIHLV
                     DGEVSKEE"
     misc_feature    complement(190230..190898)
                     /locus_tag="Smed_3747"
                     /note="ABC-type antimicrobial peptide transport system,
                     ATPase component [Defense mechanisms]; Region: SalX;
                     COG1136"
                     /db_xref="CDD:224059"
     misc_feature    complement(190242..190895)
                     /locus_tag="Smed_3747"
                     /note="ATP-binding cassette domain of the transporters
                     involved in export of lipoprotein and macrolide, and cell
                     division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255"
                     /db_xref="CDD:213222"
     misc_feature    complement(190767..190790)
                     /locus_tag="Smed_3747"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213222"
     misc_feature    complement(order(190299..190301,190398..190403,
                     190632..190634,190764..190772,190776..190781))
                     /locus_tag="Smed_3747"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213222"
     misc_feature    complement(190632..190643)
                     /locus_tag="Smed_3747"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213222"
     misc_feature    complement(190446..190475)
                     /locus_tag="Smed_3747"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213222"
     misc_feature    complement(190398..190415)
                     /locus_tag="Smed_3747"
                     /note="Walker B; other site"
                     /db_xref="CDD:213222"
     misc_feature    complement(190380..190391)
                     /locus_tag="Smed_3747"
                     /note="D-loop; other site"
                     /db_xref="CDD:213222"
     misc_feature    complement(190293..190313)
                     /locus_tag="Smed_3747"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213222"
     gene            complement(190904..192154)
                     /locus_tag="Smed_3748"
                     /db_xref="GeneID:5318738"
     CDS             complement(190904..192154)
                     /locus_tag="Smed_3748"
                     /note="PFAM: protein of unknown function DUF214;
                     KEGG: sme:SMb20369 conserved hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312494.1"
                     /db_xref="GI:150375898"
                     /db_xref="InterPro:IPR003838"
                     /db_xref="GeneID:5318738"
                     /translation="MSAMRLIFDIALTHVAGRGRQTLVAVIGVAVGVGFSIAMAALMQ
                     GGQDDFVRQLVDTMPHVDVTDEQRTARRQPAEDLFEAVAISGLRPRDDRRGIINPTKA
                     VSWLEEWMPGRLAAVLNVQGVIRYSGREVGAVVIGIEPEKEMRVSPIVEDFESGSFSA
                     LAAGGNNVVIGDTMASRLGAALGDTITAISSEGRARNFKIVGLFHTGTTARDEGEGYV
                     LLKNAQILSNRPNAINEIRIKLDDPNAAPSIAHRVEVELGYKAVAWQEANESILEALV
                     VRNVIMYTVVAAIMLVAGFGIFNIVSTITHEKARDIAIMKSLGFSETDMRRLFVIEGL
                     AIGIAGSLLGWTLGFAITYALSQVRFEIAATGQEMTRLPIAWSVLHYGIATGFALASA
                     AVAGYLPARRAARVNPVDIIRGAT"
     misc_feature    complement(190910..192145)
                     /locus_tag="Smed_3748"
                     /note="ABC-type transport system, involved in lipoprotein
                     release, permease component [Cell envelope biogenesis,
                     outer membrane]; Region: LolE; COG4591"
                     /db_xref="CDD:226957"
     misc_feature    complement(191393..192124)
                     /locus_tag="Smed_3748"
                     /note="MacB-like periplasmic core domain; Region:
                     MacB_PCD; pfam12704"
                     /db_xref="CDD:221725"
     misc_feature    complement(190931..191308)
                     /locus_tag="Smed_3748"
                     /note="FtsX-like permease family; Region: FtsX; pfam02687"
                     /db_xref="CDD:217187"
     gene            complement(192151..193173)
                     /locus_tag="Smed_3749"
                     /db_xref="GeneID:5318739"
     CDS             complement(192151..193173)
                     /locus_tag="Smed_3749"
                     /note="TIGRFAM: efflux transporter, RND family, MFP
                     subunit;
                     KEGG: sme:SMb20368 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RND family efflux transporter MFP subunit"
                     /protein_id="YP_001312495.1"
                     /db_xref="GI:150375899"
                     /db_xref="InterPro:IPR006143"
                     /db_xref="GeneID:5318739"
                     /translation="MRSKQQMRRYVVAVAAAAAVGAAAFWYALRPVPLSVVAPKRGDA
                     AEIVYASGVVEPRVWAKVTSTVRERIVEQCNCEGERVETGDALARLDDTEAQAILGEL
                     QARLSLAQEEYRRKLALAERNTISEQTVDRARTDVAQLEALIAGQEARLAAYVLRAPS
                     AGRVLRQDGEIGEVAELGTVLFWVGEPRPLIVEAEVNEEDIPRVEVGQKAYLRSDVFP
                     ERALEAVVDSITPKGDPVTKTYRVRLGLPEDTPLRIGMSTDVNIVVRLSRNALIIPAA
                     AVSGTKVAVVKSRKAMLREIKTGIRGTNGVEVLSGLEESERIISPLPPDLADGTRVDV
                     VRTEAK"
     sig_peptide     complement(193099..193173)
                     /locus_tag="Smed_3749"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.998) with cleavage site probability 0.862 at
                     residue 25"
     misc_feature    complement(192169..193071)
                     /locus_tag="Smed_3749"
                     /note="RND family efflux transporter, MFP subunit; Region:
                     RND_mfp; TIGR01730"
                     /db_xref="CDD:233547"
     misc_feature    complement(192409..192711)
                     /locus_tag="Smed_3749"
                     /note="HlyD family secretion protein; Region: HlyD_3;
                     pfam13437"
                     /db_xref="CDD:222128"
     gene            193310..194002
                     /locus_tag="Smed_3750"
                     /db_xref="GeneID:5318740"
     CDS             193310..194002
                     /locus_tag="Smed_3750"
                     /note="PFAM: regulatory protein TetR;
                     KEGG: sme:SMb20367 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_001312496.1"
                     /db_xref="GI:150375900"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="GeneID:5318740"
                     /translation="MPRVKKSPDVRTNELIECAQRLFFEQGYENTTVNDVIREANVSK
                     GAFYHYFVSKEALLEAVASRMAHQSLKELQALFEDPTLDAVGQLNALFAGSRRLKVEM
                     APQLKNTFNALFKPENIVLYHRIDAAVSAVTLPYLTGLLERGHKEGSLDAPDPEATAL
                     MLLNLRLGVAKTMHRALQQTEAGDLDGAARILDGWMRTYGLAVERLLKIPEGAIEITE
                     PGFARAFLEATV"
     misc_feature    193310..193810
                     /locus_tag="Smed_3750"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    193352..193492
                     /locus_tag="Smed_3750"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:201228"
     gene            complement(194520..195527)
                     /locus_tag="Smed_3751"
                     /db_xref="GeneID:5318741"
     CDS             complement(194520..195527)
                     /locus_tag="Smed_3751"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     SMART: regulatory protein LacI;
                     KEGG: sme:SMb20366 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001312497.1"
                     /db_xref="GI:150375901"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318741"
                     /translation="MPQKPFVSAQEVAERAGVSRSAVSRTFTPGASVSPETRRRVVEA
                     AEALGYHVNHLARGLMRNESGIVCLIVSEMSTPYRANLIRAMTQQLQNAGKIAMLINT
                     DRSDGSVDLALRQAIRYRADASIILSGMPDRSITQLCLKNGQRLVLINRDDDQQGPLR
                     INLDDAEAAGRVVTAFVRAGCRRLAFANSQAGTPSLMAREHGFVAAAKTMGLPVRVER
                     HGPTDYESGRVLAQRLLTLSERPDAVFCATDLLACGFMDAARHQFRVAIPDQLCVVGF
                     DDIEQAAWSSYDLTTFAQPVEMIAREAVAWLVNESGQAAGDDSVRFQPNLVWRSSVRG
                     G"
     misc_feature    complement(194529..195509)
                     /locus_tag="Smed_3751"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    complement(195345..195500)
                     /locus_tag="Smed_3751"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    complement(order(195348..195353,195357..195362,
                     195369..195371,195378..195380,195417..195419,
                     195426..195431,195444..195446,195453..195458,
                     195462..195476,195498..195500))
                     /locus_tag="Smed_3751"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    complement(195351..195380)
                     /locus_tag="Smed_3751"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    complement(194535..195332)
                     /locus_tag="Smed_3751"
                     /note="Ligand-binding domain of uncharacterized
                     DNA-binding regulatory proteins that are members of the
                     LacI-GalR family of bacterial transcription repressors;
                     Region: PBP1_LacI_like_2; cd06278"
                     /db_xref="CDD:107273"
     misc_feature    complement(order(194745..194750,194757..194759,
                     194769..194771,194853..194855,195168..195176,
                     195183..195185,195192..195194,195225..195227,
                     195231..195245,195264..195269,195273..195278,
                     195285..195293,195330..195332))
                     /locus_tag="Smed_3751"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:107273"
     misc_feature    complement(order(194646..194648,194697..194699,
                     194862..194864,194931..194933,195039..195041,
                     195078..195080,195147..195149,195282..195284,
                     195291..195296))
                     /locus_tag="Smed_3751"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107273"
     gene            195709..196737
                     /locus_tag="Smed_3752"
                     /db_xref="GeneID:5318742"
     CDS             195709..196737
                     /locus_tag="Smed_3752"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb20365 putative ABC transporter iron-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312498.1"
                     /db_xref="GI:150375902"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="InterPro:IPR011587"
                     /db_xref="GeneID:5318742"
                     /translation="MGLVKLAAAALAAGATFFAYSAKADGNLNLICSADVVICEQMKG
                     AFEKKSGVSVNMVRLSSGETYAKIRAEARNPKTDIWWAGTGDPHLQAASEGLTVEYKS
                     PMLGELHEWAVKQAESAGYRTVGVYAGALGWGYNTEILKQKNLKEPKCWADLLDPSFK
                     GEVQIANPNSSGTAYTALATLVQIMGEEEAFDYLKKLNANVSQYTKSGSAPVKAAARG
                     ETAIGIVFMHDAVAQTVEGFPVKSVAPCEGTGYEIGSMSIIKGAKNLDNAKKWYDWAL
                     SADVQSSMKEAKSFQLPSNKTAKVPEEAPKFEDIKLIDYDFKTYGDPAKRKELLERWD
                     REIGAAAN"
     sig_peptide     195709..195774
                     /locus_tag="Smed_3752"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.531 at
                     residue 22"
     misc_feature    195829..196641
                     /locus_tag="Smed_3752"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_8; pfam13416"
                     /db_xref="CDD:222114"
     misc_feature    195832..196728
                     /locus_tag="Smed_3752"
                     /note="ABC-type Fe3+ transport system, periplasmic
                     component [Inorganic ion transport and metabolism];
                     Region: AfuA; COG1840"
                     /db_xref="CDD:224753"
     gene            196915..199143
                     /locus_tag="Smed_3753"
                     /db_xref="GeneID:5318743"
     CDS             196915..199143
                     /locus_tag="Smed_3753"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20364 putative iron ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312499.1"
                     /db_xref="GI:150375903"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318743"
                     /translation="MKTHNRRLDIVLALGLAAFTIFPWYRIDGGFFGFGWLSGFPVEP
                     AVAPGFLQIAAFGKWWLVLPALAVLAALSVRFIGDAARRGSLLAWAGAAGIVIMALQG
                     LAIGLSGWNWTISEAMLGTLADGQPPMGAGAVLAALVFVFIFAFGLAERGVMKGDAFA
                     VASISLLVFLVAVFVFYPVGSMLVGAFQDFDGSFNPEGFSRNIVDPSIWSLDCVIGGR
                     RCGIAWRTFWLAVMTAGGSTILGLAFALLATRTAFPYKRSLRLLTVLPIITPPFVVGL
                     ALTLLFGRSGVITEAMSTLIGVEPGRWLYGLTGIWIAQVLSFTPISFLVLIGVVEGVS
                     PSMEEASQTLRANRWRTFWRISLPLMKPGLANAFLIGFIESMADFGNPLVLGGSHGVL
                     STEIFFAVVGSQNDPSRAAVLAIILLCFTLTAFLAQRFWLSGKSYATVTGKGDSGAHA
                     ALPRTVSIAVHVLVIPWALFTLVVYGMILVGGFVKTWGLDNSLTLAHYAKAFSVELRD
                     GGIAWTGVAWNSFWTTMEIALISAPLTAAVGLLTAYLIVRQKFAGRELFEFALMMSFA
                     IPGTVIGISYIMAFNLPPLEMTGSALILVACFVFRNMPVGVRGGVAAMSQLDRSLDEA
                     SLTLRADSFRTIRKVILPLLRPAITAALVYSFVRAITSISAVIFLVSAEYNMATAYIV
                     GLVENGEYGVAIAYSSMLIVVMIAVIAGFQLIVGERRLRRENRIQAVAGVPVPLPQEK
                     TA"
     misc_feature    197443..199080
                     /locus_tag="Smed_3753"
                     /note="ABC-type Fe3+ transport system, permease component
                     [Inorganic ion transport and metabolism]; Region: ThiP;
                     COG1178"
                     /db_xref="CDD:224099"
     misc_feature    197581..198183
                     /locus_tag="Smed_3753"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(197629..197634,197641..197646,197659..197661,
                     197689..197700,197704..197733,197740..197745,
                     197749..197751,197860..197865,197869..197871,
                     197875..197877,197884..197889,197893..197895,
                     197905..197910,197917..197919,197968..197970,
                     198010..198015,198022..198024,198043..198054,
                     198061..198066,198103..198108,198136..198141,
                     198148..198153,198157..198162,198169..198174,
                     198181..198183)
                     /locus_tag="Smed_3753"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(197707..197751,198043..198060)
                     /locus_tag="Smed_3753"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(197749..197751,197842..197844,198061..198063,
                     198097..198099,198106..198108,198136..198138)
                     /locus_tag="Smed_3753"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(197920..197958,197974..197979,197989..197991)
                     /locus_tag="Smed_3753"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     misc_feature    198475..199038
                     /locus_tag="Smed_3753"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(198523..198528,198535..198540,198553..198555,
                     198583..198594,198598..198627,198634..198636,
                     198637..198639,198712..198717,198721..198723,
                     198727..198729,198736..198741,198745..198747,
                     198757..198762,198769..198771,198820..198822,
                     198862..198867,198874..198876,198895..198906,
                     198913..198918,198955..198960,198988..198993,
                     199000..199005,199009..199014,199021..199026,
                     199033..199038)
                     /locus_tag="Smed_3753"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(198601..198636,198637..198639,198895..198912)
                     /locus_tag="Smed_3753"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(198637..198639,198697..198699,198913..198915,
                     198949..198951,198958..198960,198988..198990)
                     /locus_tag="Smed_3753"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(198772..198810,198826..198831,198841..198843)
                     /locus_tag="Smed_3753"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            199140..200201
                     /locus_tag="Smed_3754"
                     /db_xref="GeneID:5318744"
     CDS             199140..200201
                     /locus_tag="Smed_3754"
                     /note="PFAM: ABC transporter related; Transport-associated
                     OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20363 putative iron ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312500.1"
                     /db_xref="GI:150375904"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5318744"
                     /translation="MTIVAPGSVVFRNVRKQFGVFTAIPDLSLTIEPGTLVTLLGPSG
                     CGKTTTLRMLAGLEHPTSGRILIGGKDVTMLPANERDVSMVFQSYALFPHMNALDNVA
                     YGLESSGIKRNEARQRAEEGLALVGLPGMGQRLPAELSGGQQQRVAVARALVLEPQVL
                     LLDEPLSNLDARLRRRVRTEIRELQQRLGFTAVYVTHDQDEALAVSDRIIVMKDGNIA
                     QEGAPRELYETPASAFIADFMGEANVVACDVIHVDGHEATVRVEQLTHRVRGRGMRPG
                     PAKLAVRPNAIALEAATGGSFSGEITHTAYLGDHVEYEVKTAAGTLFVVDTAVERALA
                     PQTNVAIAFKERGIAVISG"
     misc_feature    199152..200192
                     /locus_tag="Smed_3754"
                     /note="ABC-type spermidine/putrescine transport systems,
                     ATPase components [Amino acid transport and metabolism];
                     Region: PotA; COG3842"
                     /db_xref="CDD:226361"
     misc_feature    199164..199859
                     /locus_tag="Smed_3754"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    199260..199283
                     /locus_tag="Smed_3754"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(199269..199274,199278..199286,199398..199400,
                     199626..199631,199728..199730)
                     /locus_tag="Smed_3754"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    199389..199400
                     /locus_tag="Smed_3754"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    199554..199583
                     /locus_tag="Smed_3754"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    199614..199631
                     /locus_tag="Smed_3754"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    199638..199649
                     /locus_tag="Smed_3754"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    199716..199736
                     /locus_tag="Smed_3754"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     misc_feature    199977..200192
                     /locus_tag="Smed_3754"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            200255..201055
                     /locus_tag="Smed_3755"
                     /db_xref="GeneID:5318745"
     CDS             200255..201055
                     /locus_tag="Smed_3755"
                     /EC_number="3.1.3.25"
                     /note="PFAM: inositol monophosphatase;
                     KEGG: sme:SMb20362 putative inositol monophosphatase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-phosphate phosphatase"
                     /protein_id="YP_001312501.1"
                     /db_xref="GI:150375905"
                     /db_xref="InterPro:IPR000760"
                     /db_xref="GeneID:5318745"
                     /translation="MTSHVVPGLEARLALAETIAREAGAVALEYFTRRETLIIETKRD
                     PQDLVSIADREVETLIRDRIAEAYPEDGVLGEEYGLVPGSSGFTWAVDPIDGTSPFVN
                     GMPNWCVSIALVHAGVAVVGVIAAPCYGELYAAALGLGARLNGKTLAIDGSRTIRNHV
                     TGLGANNYVKPAFVGKMVENLLEAGGTFIRNGSGALMLAYVAAGRLVGYYEPYMHAWD
                     CLAGYCLVKEAGGWYLPFPTDGEGLTKGAAVLAAAPGAVEDLRKLAGI"
     misc_feature    200279..200986
                     /locus_tag="Smed_3755"
                     /note="Archaeal fructose-1,6-bisphosphatase and related
                     enzymes of inositol monophosphatase family [Carbohydrate
                     transport and metabolism]; Region: SuhB; COG0483"
                     /db_xref="CDD:223559"
     misc_feature    200291..200989
                     /locus_tag="Smed_3755"
                     /note="FIG, FBPase/IMPase/glpX-like domain. A superfamily
                     of metal-dependent phosphatases with various substrates.
                     Fructose-1,6-bisphospatase (both the major and the
                     glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate
                     to fructose-6-phosphate in...; Region: FIG; cl00289"
                     /db_xref="CDD:241756"
     misc_feature    order(200411..200413,200480..200485,200528..200542,
                     200906..200908)
                     /locus_tag="Smed_3755"
                     /note="active site"
                     /db_xref="CDD:238814"
     gene            201391..201615
                     /locus_tag="Smed_3756"
                     /db_xref="GeneID:5318746"
     CDS             201391..201615
                     /locus_tag="Smed_3756"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312502.1"
                     /db_xref="GI:150375906"
                     /db_xref="GeneID:5318746"
                     /translation="MCKHFAHKIAVEQVDDCAELRFSCGTGYLKSAPDGLHIRVVSAD
                     DADLAQVQARHRRPPPAFRENAGPLHWTDF"
     misc_feature    201391..201606
                     /locus_tag="Smed_3756"
                     /note="Uncharacterized protein conserved in bacteria
                     (DUF2218); Region: DUF2218; cl01424"
                     /db_xref="CDD:242498"
     gene            201637..201837
                     /locus_tag="Smed_3757"
                     /db_xref="GeneID:5318747"
     CDS             201637..201837
                     /locus_tag="Smed_3757"
                     /note="KEGG: rpb:RPB_4397 transport system permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312503.1"
                     /db_xref="GI:150375907"
                     /db_xref="GeneID:5318747"
                     /translation="MAADRLTVLSLGRDVSIGLGPNYQRTLQLGLVIVSVISALTVVV
                     VGIIPFGRQSAGTFPGWRLAAA"
     misc_feature    <201640..>201786
                     /locus_tag="Smed_3757"
                     /note="Transmembrane subunit (TM), of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters involved in the uptake of siderophores, heme,
                     vitamin B12, or the divalent cations Mg2+ and Zn2+.
                     PBP-dependent ABC transporters consist of...; Region:
                     TM_ABC_iron-siderophores_like; cl00462"
                     /db_xref="CDD:241879"
     gene            202007..202906
                     /locus_tag="Smed_3758"
                     /db_xref="GeneID:5318748"
     CDS             202007..202906
                     /locus_tag="Smed_3758"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR; KR
                     domain protein;
                     KEGG: sus:Acid_3006 short-chain dehydrogenase/reductase
                     SDR"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001312504.1"
                     /db_xref="GI:150375908"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5318748"
                     /translation="MARQDLSGKVVVITGASSGFGKGAARRFAREGCSLVLAARRGNL
                     LDELARECRSLGAPALAIEADVSDRERVARLASAALAEYGRIDIWVNNAGVGAIGPFE
                     DIPLEDQAKVVETNLLGTLYGSFHAYRQFRQQGSGILINIASELGRETVPYYAAYTAS
                     KHGVIGLCDSLRQEVKQAGQENIHICAIMPTAHDTPFFDHVANYSGHEVRPPTPLHDP
                     ENVADAILAAARDPSNEDIVGWDGAIKIAAKRFLPGAADAVMARMMHKTQMGAPPATN
                     SPGAVHSPVQDGTEVSGGRRAKG"
     misc_feature    202019..202813
                     /locus_tag="Smed_3758"
                     /note="Short-chain dehydrogenases of various substrate
                     specificities [General function prediction only]; Region:
                     DltE; COG0300"
                     /db_xref="CDD:223377"
     misc_feature    202034..202723
                     /locus_tag="Smed_3758"
                     /note="classical (c) SDR, subgroup 3; Region: SDR_c3;
                     cd05360"
                     /db_xref="CDD:187618"
     misc_feature    order(202049..202051,202055..202066,202121..202129,
                     202196..202204,202280..202288,202349..202351,
                     202430..202438,202475..202477,202487..202489,
                     202574..202585,202589..202594)
                     /locus_tag="Smed_3758"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187618"
     misc_feature    order(202352..202354,202436..202438,202475..202477,
                     202487..202489)
                     /locus_tag="Smed_3758"
                     /note="active site"
                     /db_xref="CDD:187618"
     gene            202969..203766
                     /locus_tag="Smed_3759"
                     /db_xref="GeneID:5318749"
     CDS             202969..203766
                     /locus_tag="Smed_3759"
                     /note="PFAM: Ion transport protein; Ion transport 2 domain
                     protein;
                     KEGG: sme:SMb20361 putative ionic voltage-gated channel
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Ion transport 2 domain-containing protein"
                     /protein_id="YP_001312505.1"
                     /db_xref="GI:150375909"
                     /db_xref="InterPro:IPR003091"
                     /db_xref="InterPro:IPR005821"
                     /db_xref="InterPro:IPR013099"
                     /db_xref="GeneID:5318749"
                     /translation="MDMTDQPRAHSKLNSIRLALQRLERGRDPWALRWQALLAIIDLS
                     ILAFFILGPYLRAGPSYLIIDYIIAAWIGCELIARAFAAPSVKRFLRRPMTWVDVVIL
                     GTLLFPDLLFNFAFLRVMRIWAIGKSPLLLEGLRRAGWSHLQEVVRACLNFLVFLFVV
                     TGFVYTTFFYHREGGEGFVDALYFTVATITTTGFGDITLPGALGKLTSVVTMIVGISL
                     FVRLAQAVVRPYKVHFPCPQCGLQRHDTDAVHCKACGYMLNIPDEGD"
     misc_feature    203146..203736
                     /locus_tag="Smed_3759"
                     /note="Kef-type K+ transport systems, predicted
                     NAD-binding component [Inorganic ion transport and
                     metabolism]; Region: Kch; COG1226"
                     /db_xref="CDD:224147"
     misc_feature    <203500..203628
                     /locus_tag="Smed_3759"
                     /note="Ion channel; Region: Ion_trans_2; pfam07885"
                     /db_xref="CDD:219619"
     gene            complement(203807..204595)
                     /locus_tag="Smed_3760"
                     /db_xref="GeneID:5319052"
     CDS             complement(203807..204595)
                     /locus_tag="Smed_3760"
                     /note="KEGG: sme:SMb20360 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312506.1"
                     /db_xref="GI:150375910"
                     /db_xref="GeneID:5319052"
                     /translation="MRIDDAFKALMRLDDGVLMRGAFFVMLSAAGIFLLIDMREIAAM
                     NAGLPGFDPMLEDSPVLPPAVTEAAPKGSPVHPASSDEVLRQPMRFELGSGGVLLAEG
                     TIDLGAAARFAQEIEARGEYVKTVALNSPGGSVEDALAISKLIREKKLDTKIASRALC
                     ASSCPIVFAGGVARVAASDALIGVHQVFSGGGDDRSTPAQAMSFAQSTTARVARHLDT
                     MGIGAGLWINALETPPERLYYLTTKEMAEFHLITEPVETAKKKE"
     misc_feature    complement(203819..204541)
                     /locus_tag="Smed_3760"
                     /note="Predicted periplasmic protein [Function unknown];
                     Region: COG3904"
                     /db_xref="CDD:226419"
     gene            complement(204582..205883)
                     /locus_tag="Smed_3761"
                     /db_xref="GeneID:5319053"
     CDS             complement(204582..205883)
                     /locus_tag="Smed_3761"
                     /note="KEGG: sme:SMb20359 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312507.1"
                     /db_xref="GI:150375911"
                     /db_xref="GeneID:5319053"
                     /translation="MALGASQRLNDGVAAVETMTRFALAVLALASGVYTYLGVRSILD
                     GSPTAVFFAAIIYSASVSVGIYAFWSYMARFYPHVTTHAGRVAMLGVMALGAAMIIAM
                     SSWLNAAALAGSAALEQHLAETVEDYTADLDQAHQNALAAQSLLPDIQRASERFAQLA
                     ASERQSGALTGTTGSGSVVQLLSQMSAQMKDLENGINASREQVAMLFNQGQERLETMR
                     TLVSAPGAVTPRADQFSSEVVALTGVITSLGQTSIAPSIRRAADDLSLGFIAPVADGG
                     DADLVTRQDQVMETVRASVAAQSKVLSDAADEILGRMPVAERRFVPLSSAEAVLRYAA
                     DFIPAWAGAISIDLLPGVLVFILATVHGAIRRQEEKLPFAERITAAELLQALEVQRAV
                     MANGGQNGEAGDSVEMEGDEPNNITSLDPRVRVKDRSHEDR"
     gene            complement(206007..207569)
                     /locus_tag="Smed_3762"
                     /db_xref="GeneID:5319054"
     CDS             complement(206007..207569)
                     /locus_tag="Smed_3762"
                     /EC_number="4.6.1.2"
                     /note="PFAM: adenylyl cyclase class-3/4/guanylyl cyclase;
                     response regulator receiver; histidine kinase A domain
                     protein;
                     KEGG: sme:SMb20358 putative regulatory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenylate/guanylate cyclase"
                     /protein_id="YP_001312508.1"
                     /db_xref="GI:150375912"
                     /db_xref="InterPro:IPR001054"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="GeneID:5319054"
                     /translation="MTAINDFQRQAIAAHVAQRLAGPARAILSFQELLIEQARDLGLL
                     HTKSDIDRIGAAARQLNNLIDSLLDGTACSLKEGAAEAEARFRHDLRTPLNAIIGYSE
                     MILEEARDSQQHALTEDLQVILSAAAELLKQVDAIASLSRGEVAEVLQPEERVDIDAA
                     GLERLLSTAEQTALPDRVGRILVVDDVASNRDLLSRRLRREGHRVVTAESGRSALARL
                     AEEEFDLILLDILMPDMNGIQMLSRLKSEGRWQHIPVIMISGLSEVTAVARCIEAGAD
                     DYLTKPFNPILLRARINSTLEKKRWLDREHRYLQQIEAEKSRADSLIRAILPDQIVSR
                     LQNGEEIIADRFEEVSILFADIVGFSPIAARLTPSDLVRCLDRMFRQFDLLTEQHGVE
                     KIKTIGDSYMAACGIPEPTTDHADRIVALGKSMLRSLRDMEPEQERFRIRIGIHSGPV
                     VAGLIGRLRFVYDVWGETVNIASRLESQGVPDGIQISDATRRALQGQWALDRRSAQNL
                     RGIGAVETFLVR"
     misc_feature    complement(<207006..207497)
                     /locus_tag="Smed_3762"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: BaeS; COG0642"
                     /db_xref="CDD:223715"
     misc_feature    complement(207144..207308)
                     /locus_tag="Smed_3762"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    complement(207306..207308)
                     /locus_tag="Smed_3762"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    complement(order(207159..207161,207171..207173,
                     207180..207182,207192..207194,207201..207203,
                     207213..207215,207270..207272,207279..207281,
                     207291..207293,207300..207302))
                     /locus_tag="Smed_3762"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    complement(206691..207029)
                     /locus_tag="Smed_3762"
                     /note="Response regulator receiver domain; Region:
                     Response_reg; pfam00072"
                     /db_xref="CDD:200976"
     misc_feature    complement(206682..207026)
                     /locus_tag="Smed_3762"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(206724..206729,206736..206738,
                     206793..206795,206859..206861,206883..206885,
                     207012..207017))
                     /locus_tag="Smed_3762"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(206883..206885)
                     /locus_tag="Smed_3762"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(206859..206867,206871..206876))
                     /locus_tag="Smed_3762"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(206721..206729)
                     /locus_tag="Smed_3762"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(206082..206630)
                     /locus_tag="Smed_3762"
                     /note="Adenylyl- / guanylyl cyclase, catalytic domain;
                     Region: CYCc; smart00044"
                     /db_xref="CDD:214485"
     misc_feature    complement(206013..206528)
                     /locus_tag="Smed_3762"
                     /note="cyclase homology domain; Region: CHD; cd07302"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(206043..206045,206148..206153,
                     206160..206165,206175..206183,206364..206366,
                     206373..206381,206385..206387,206490..206507,
                     206511..206513))
                     /locus_tag="Smed_3762"
                     /note="nucleotidyl binding site; other site"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(206373..206375,206505..206507))
                     /locus_tag="Smed_3762"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(206043..206045,206160..206162,
                     206169..206180,206208..206210,206217..206219,
                     206382..206387,206421..206423,206433..206435,
                     206442..206447,206454..206456,206490..206492))
                     /locus_tag="Smed_3762"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143636"
     gene            complement(207577..207942)
                     /locus_tag="Smed_3763"
                     /db_xref="GeneID:5319055"
     CDS             complement(207577..207942)
                     /locus_tag="Smed_3763"
                     /note="PFAM: response regulator receiver;
                     KEGG: sme:SMb20357 putative histidine kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver protein"
                     /protein_id="YP_001312509.1"
                     /db_xref="GI:150375913"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="GeneID:5319055"
                     /translation="MTRILLVEDNEMNRDMLSRRLSRRGFEVLIAENGQAGVELAASE
                     KPDLILMDMSLPVMDGWEATRRIKADPLTSAIPVIALTAHAMASDREMALKAGCDDYD
                     SKPVDLPQLVRKIEQLLTT"
     misc_feature    complement(207595..207933)
                     /locus_tag="Smed_3763"
                     /note="Response regulator receiver domain; Region:
                     Response_reg; pfam00072"
                     /db_xref="CDD:200976"
     misc_feature    complement(207586..207930)
                     /locus_tag="Smed_3763"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(207628..207633,207640..207642,
                     207697..207699,207763..207765,207787..207789,
                     207916..207921))
                     /locus_tag="Smed_3763"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(207787..207789)
                     /locus_tag="Smed_3763"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(207763..207771,207775..207780))
                     /locus_tag="Smed_3763"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(207625..207633)
                     /locus_tag="Smed_3763"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     gene            complement(207968..210721)
                     /locus_tag="Smed_3764"
                     /db_xref="GeneID:5319056"
     CDS             complement(207968..210721)
                     /locus_tag="Smed_3764"
                     /note="TIGRFAM: PAS sensor protein;
                     PFAM: response regulator receiver; ATP-binding region
                     ATPase domain protein; histidine kinase HAMP region domain
                     protein; histidine kinase A domain protein;
                     KEGG: sme:SMb20356 putative sensory histidine kinase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="multi-sensor hybrid histidine kinase"
                     /protein_id="YP_001312510.1"
                     /db_xref="GI:150375914"
                     /db_xref="InterPro:IPR000014"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003660"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="GeneID:5319056"
                     /translation="MSALGHGLRSTEAVRPTKRLDSRIIDLPISARVAALTAAGLVSL
                     VLSSLFLTQALYRSAERMAETRELFDRAASAASAHVAFGDLRYWLTDLSVSLLMNSQR
                     NADEARARLQVQLERLARHAPVEVRQIGAEVDAYMETALQAADSYTQDNRIVGNALLA
                     KARTHSGKVDTDLNRLVEQVKAEAEAARNEVVVQTEKTATTAAILVGGVVLIGSLLTL
                     LVLRSIVGPLRRLNRVIGDLTEGRYDVEIPQEGGDEFGAMARTLSLFQESAIEKKKLE
                     DEAERQRRTIAAALEVISDGFVLYDSDDRILVANSKYCEIFPSHKPNTLRGRSFREIV
                     EQNLETGQVDLEGKSPQEWVDERVRLHRDPAGLVDEKRFGERWVRISKRKIPDGGTVA
                     VYTDITELKQRQVELERAKSHAESANEAKSQFLASMSHELRTPLNAIIGYSEMLIEEA
                     RDHKEEELVPDLDKIASAGRHLLTLINDILDLSKIEANKMDVFLETFSLAELLRDVAA
                     TVAPLMARNGNAFTQDFEDDLGKMHSDQTKLRQNLFNLLSNAAKFTKGGRVILRVRRE
                     QRAEHDWLVFQVSDTGIGMTPEQQDRLFNAFTQADASTTRNYGGTGLGLSITRSFCRL
                     IGGVVTVESEAGKGSVFTMEVPAKCESEVDRPPPEQAAQVRSGRTALIIDDEPAARNL
                     IAKALAEAGLAAIEASNGQEGLAAAREHRPDAIILDIIMPHQDGWSVLRALKNDPELC
                     TIPVILATILADRELGLSLGAVEYLTKPIDTDKLVRTIETFGGGKHDVLVIDDDQGSR
                     EFLRRILVKRKWTVHEAGDGVRGLEMMKRLLPRLVLLDLLMPEMDGFQTLSEMQSIPE
                     LQNIPVVVVTSKDLSANELKWLRDRAVAVVNKGANSRAQLVEALERQIGSVALIGKEL
                     AEG"
     misc_feature    complement(209918..210043)
                     /locus_tag="Smed_3764"
                     /note="Histidine kinase, Adenylyl cyclase,
                     Methyl-accepting protein, and Phosphatase (HAMP) domain.
                     HAMP is a signaling domain which occurs in a wide variety
                     of signaling proteins, many of which are bacterial. The
                     HAMP domain consists of two alpha helices...; Region:
                     HAMP; cd06225"
                     /db_xref="CDD:100122"
     misc_feature    complement(order(209918..209920,209927..209932,
                     209936..209941,209948..209953,209957..209962,
                     210008..210010,210014..210019,210026..210031,
                     210035..210040))
                     /locus_tag="Smed_3764"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100122"
     misc_feature    complement(208796..209884)
                     /locus_tag="Smed_3764"
                     /note="phosphate regulon sensor kinase PhoR; Region:
                     phoR_proteo; TIGR02966"
                     /db_xref="CDD:234074"
     misc_feature    complement(<209720..209872)
                     /locus_tag="Smed_3764"
                     /note="PAS domain; Region: PAS; smart00091"
                     /db_xref="CDD:214512"
     misc_feature    complement(209270..209470)
                     /locus_tag="Smed_3764"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    complement(order(209285..209287,209297..209299,
                     209306..209308,209318..209320,209327..209329,
                     209339..209341,209396..209398,209405..209407,
                     209417..209419,209426..209428,209438..209440,
                     209450..209452))
                     /locus_tag="Smed_3764"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    complement(209432..209434)
                     /locus_tag="Smed_3764"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    complement(208787..209107)
                     /locus_tag="Smed_3764"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(208799..208801,208805..208810,
                     208823..208825,208829..208831,208877..208888,
                     208967..208972,208976..208978,208982..208984,
                     208988..208990,209066..209068,209075..209077,
                     209087..209089))
                     /locus_tag="Smed_3764"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(209075..209077)
                     /locus_tag="Smed_3764"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(208880..208882,208886..208888,
                     208970..208972,208976..208978))
                     /locus_tag="Smed_3764"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(208385..208711)
                     /locus_tag="Smed_3764"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(208385..208711)
                     /locus_tag="Smed_3764"
                     /note="Response regulator receiver domain; Region:
                     Response_reg; pfam00072"
                     /db_xref="CDD:200976"
     misc_feature    complement(order(208418..208423,208430..208432,
                     208478..208480,208544..208546,208568..208570,
                     208697..208702))
                     /locus_tag="Smed_3764"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(208568..208570)
                     /locus_tag="Smed_3764"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(208544..208552,208556..208561))
                     /locus_tag="Smed_3764"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(208415..208423)
                     /locus_tag="Smed_3764"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(207995..208360)
                     /locus_tag="Smed_3764"
                     /note="FOG: CheY-like receiver [Signal transduction
                     mechanisms]; Region: CheY; COG0784"
                     /db_xref="CDD:223855"
     misc_feature    complement(208010..208357)
                     /locus_tag="Smed_3764"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(208124..208126,208190..208192,
                     208214..208216,208343..208348))
                     /locus_tag="Smed_3764"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(208214..208216)
                     /locus_tag="Smed_3764"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(208190..208198,208202..208207))
                     /locus_tag="Smed_3764"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     gene            complement(210718..211476)
                     /locus_tag="Smed_3765"
                     /db_xref="GeneID:5319057"
     CDS             complement(210718..211476)
                     /locus_tag="Smed_3765"
                     /note="KEGG: sme:SMb20355 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312511.1"
                     /db_xref="GI:150375915"
                     /db_xref="GeneID:5319057"
                     /translation="MGALTALARNCIVTALFGCALFAPSIAAEEAADVATGTRLAELL
                     RAARNVLSNYQSLINDPAIGDKKLNGERFTTEAIAFYGERTGHPLISDDLGDRDRKLL
                     QAQVEAMREVVDEEQDDINRPGIGFKGFVPAIFARLMNEKFAVKAGNEALVRVTAPEV
                     LVRNRKSLPDAWEARVINEIFSDPKRPKGELYTEVTQVNGRPAFRMLLPEYYTESCLS
                     CHGSPKGEIDVTGYPKEGGKAGDLGGAISIVLFK"
     sig_peptide     complement(211393..211476)
                     /locus_tag="Smed_3765"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.995) with cleavage site probability 0.510 at
                     residue 28"
     misc_feature    complement(210727..211245)
                     /locus_tag="Smed_3765"
                     /note="Protein of unknown function (DUF3365); Region:
                     DUF3365; pfam11845"
                     /db_xref="CDD:221261"
     gene            complement(211541..212599)
                     /locus_tag="Smed_3766"
                     /db_xref="GeneID:5319058"
     CDS             complement(211541..212599)
                     /locus_tag="Smed_3766"
                     /note="PFAM: oxidoreductase domain protein; Oxidoreductase
                     domain;
                     KEGG: sme:SMb20353 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain-containing protein"
                     /protein_id="YP_001312512.1"
                     /db_xref="GI:150375916"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="GeneID:5319058"
                     /translation="MADLKGALIGCGFFAVNQMHGWRDAEGARIVSICDRDPERLRAV
                     GDEFGITRRYLSVDDLFADGGFDFVDIATTVGSHRSLVELAARHGIATICQKPIAPTM
                     EDAEAMVEACAKAGVPFMVHENFRWQSPIRAVKAAIDSGTVGEVFWGRVSFRSGYDVF
                     SGQPYLATGKRFIIEDLGIHALDVARYIFGDATAVTARTRRVNPAIAGEDVATMLLDH
                     EGAITSIVDCSYATRLPIEPFPETLIEVDGSKGTLRLSQGYHLTMHSKDGTKVTNVEP
                     PVLSWAAPPWHNIQESVSRIQQHWVEALRAGREPDTSGLDNLETFALVEASYLSAAEG
                     RTVSLAEVIGRRPSQFSR"
     misc_feature    complement(211577..212599)
                     /locus_tag="Smed_3766"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:223745"
     misc_feature    complement(212237..212581)
                     /locus_tag="Smed_3766"
                     /note="Oxidoreductase family, NAD-binding Rossmann fold;
                     Region: GFO_IDH_MocA; pfam01408"
                     /db_xref="CDD:201778"
     misc_feature    complement(211889..212197)
                     /locus_tag="Smed_3766"
                     /note="Oxidoreductase family, C-terminal alpha/beta
                     domain; Region: GFO_IDH_MocA_C; pfam02894"
                     /db_xref="CDD:217272"
     gene            complement(212604..213668)
                     /locus_tag="Smed_3767"
                     /db_xref="GeneID:5319059"
     CDS             complement(212604..213668)
                     /locus_tag="Smed_3767"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20352 probable sugar ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001312513.1"
                     /db_xref="GI:150375917"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5319059"
                     /translation="MTTATTTTTATDAASGSVLLTLMKLRTFIALFAVIAFFSIFAPN
                     FLSTANLILMSKHVALNAFLAMGMTFVIITGGIDLSVGSIVGLCGMVAGGLILNGIDL
                     QFGYTIYFNVVEVCLITLAVGIVIGAVNGLLITKLNVAPFIATLGTLYVARGFALLSS
                     GGQTFPNLVGKPELSTTGFAFLGSGRLLGLPVSIWILIVVALAAAYLARYTPIGRHIF
                     AVGGNERAARMSGIRVNRVKMFVYMFSGFCAAIVGLVISSELMASHPATGNSFELNAI
                     AAAVLGGTSMSGGRGTIGGTIIGAFVIGILSDGLVMMGISSFWQMVIKGIVIIVAVVV
                     DQAQRRLQQQVTLMQLAKKG"
     misc_feature    complement(212706..213497)
                     /locus_tag="Smed_3767"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(212826..213485)
                     /locus_tag="Smed_3767"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(212940..212996)
                     /locus_tag="Smed_3767"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(213668..215212)
                     /locus_tag="Smed_3768"
                     /db_xref="GeneID:5319060"
     CDS             complement(213668..215212)
                     /locus_tag="Smed_3768"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20351 probable sugar ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312514.1"
                     /db_xref="GI:150375918"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319060"
                     /translation="MQARDDDDCILRLEDVTKVYSGIVAVRHADLSLRRGAVNVLVGE
                     NGAGKSTLMRIIAGVEKPSLGRILLDGKEVEFHSPADAQRHGIGMVFQELNLFGNLSV
                     AENIFATRELTRGFRGIDHRAQVERATGFLDRLDAGIDAETLVEDLPIGQQQLVEIAK
                     AISLDTRILILDEPTSALSAAEVDVLFKVIRELKAQGVAIVYISHRLEELMRIGDYIT
                     VLRDGQITGHAMVKDIDTKWIVRSMIGSDAKDFAKSIAHRLGEEAFRAEDICLPRRTG
                     GLAVDHVSISLRAGEVLGIYGLMGAGRSEFFECVMGQHPHSSGRVFVDGIEIDATDTA
                     GRISAGLALIPEDRQREGLVQALSIASNLTLASLDRFVRFGFHIVGAREQASIEAAIR
                     DLSIKAPNPDFEVTSMSGGNQQKVVIGKALMTKPKVLLMDEPSRGIDVGAKADVFRTM
                     RRLAGEGLAILFSTSDLEEVMALSDRIAVMSNGRLVTVVGRADATEEMIVKASAEGHK
                     TTREHA"
     misc_feature    complement(213695..215206)
                     /locus_tag="Smed_3768"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    complement(214529..215182)
                     /locus_tag="Smed_3768"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    complement(215063..215086)
                     /locus_tag="Smed_3768"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(214598..214600,214694..214699,
                     214937..214939,215060..215068,215072..215077))
                     /locus_tag="Smed_3768"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(214937..214948)
                     /locus_tag="Smed_3768"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(214742..214762,214907..214915))
                     /locus_tag="Smed_3768"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(214694..214711)
                     /locus_tag="Smed_3768"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(214676..214687)
                     /locus_tag="Smed_3768"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(214592..214612)
                     /locus_tag="Smed_3768"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(213758..214435)
                     /locus_tag="Smed_3768"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            complement(215215..215859)
                     /locus_tag="Smed_3769"
                     /db_xref="GeneID:5319061"
     CDS             complement(215215..215859)
                     /locus_tag="Smed_3769"
                     /note="KEGG: sme:SMb20350 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312515.1"
                     /db_xref="GI:150375919"
                     /db_xref="GeneID:5319061"
                     /translation="MPNFKVAAALAVAGVMALSGCKIIKTPTAEEAAEAASGGFNPNR
                     MVAEIWDTKVLSYLDRKAGPFTEVAALAGSDPQAAGAKYGHKEKQGSAPWTFAARLSG
                     TIVKAETKSRSAYVEVDADADGKADARVQIGPAIRGTAIRDSLDFVNFNEFKNQIEWA
                     QFGKAFNTHVNGLVLEKLPRDGLVGKKLDAVGAYPLPAKGQLPMFVPARLTVGG"
     misc_feature    complement(215218..215859)
                     /locus_tag="Smed_3769"
                     /note="Predicted periplasmic lipoprotein [General function
                     prediction only]; Region: COG5618"
                     /db_xref="CDD:227905"
     sig_peptide     complement(215797..215859)
                     /locus_tag="Smed_3769"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.876) with cleavage site probability 0.310 at
                     residue 21"
     gene            complement(215969..216910)
                     /locus_tag="Smed_3770"
                     /db_xref="GeneID:5318218"
     CDS             complement(215969..216910)
                     /locus_tag="Smed_3770"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     KEGG: sme:SMb20349 probable ABC transporter sugar-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001312516.1"
                     /db_xref="GI:150375920"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318218"
                     /translation="MKLTRRMTIAAFAAVLAASSAIPAYAADLIAIITPSHDNPFFKA
                     EAVGAEAKAKELGYETLVLVHDDDANKQSQLIDTAIGRGAKAIILDNAGSEASIAAVQ
                     KAKDAGVPSFLIDREINATGVAVSQIVSNNYQGAQLGAEEFVKLMGESGNYVELLGRE
                     ADLNAGIRSKGYHDVIDEYPEMKMVAQQSANWSQTEGYSKMETILQANPDIKGVISGN
                     DTMAMGAIAALHAAGRKDVIVVGFDGSNDVRDSIKSGGIKATVLQPAYAQAQMAVQQA
                     HEYITTGKTPAEEKQLMDCVLINSENAGQLETFALID"
     sig_peptide     complement(216830..216910)
                     /locus_tag="Smed_3770"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 27"
     misc_feature    complement(216014..216826)
                     /locus_tag="Smed_3770"
                     /note="Periplasmic sugar-binding domain of the
                     thermophilic Thermoanaerobacter tengcongensis ribose
                     binding protein (ttRBP) and its mesophilic homologs;
                     Region: PBP1_ribose_binding; cd06323"
                     /db_xref="CDD:107318"
     misc_feature    complement(216125..216823)
                     /locus_tag="Smed_3770"
                     /note="Periplasmic binding protein domain; Region:
                     Peripla_BP_4; pfam13407"
                     /db_xref="CDD:222108"
     misc_feature    complement(order(216122..216124,216182..216184,
                     216257..216259,216335..216337,216407..216409,
                     216419..216421,216563..216568,216641..216643,
                     216785..216790,216794..216796))
                     /locus_tag="Smed_3770"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107318"
     misc_feature    complement(order(216293..216295,216347..216352,
                     216359..216364,216401..216403,216413..216415))
                     /locus_tag="Smed_3770"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107318"
     gene            complement(216978..217802)
                     /locus_tag="Smed_3771"
                     /db_xref="GeneID:5318219"
     CDS             complement(216978..217802)
                     /locus_tag="Smed_3771"
                     /note="PFAM: NADP oxidoreductase coenzyme F420-dependent;
                     KEGG: sme:SMb20348 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-dependent NADP oxidoreductase"
                     /protein_id="YP_001312517.1"
                     /db_xref="GI:150375921"
                     /db_xref="InterPro:IPR004455"
                     /db_xref="GeneID:5318219"
                     /translation="MTSIALFGAGGKMGCRLAKNLKGSRFDVRHVEVSEAGKVRLAEL
                     GLSTVDADAALDGAEVVVLAVPDTAIGKVASAIADRLKPGTMVIVLDAAAPYAGHLPE
                     RSDLTYFVTHPCHPPIFNDETDPAAKRDFFGGVAARQHIVSALMQGPEEAYALGEEIA
                     KIIWAPVMRSHRVTVEQIALLEPGLSETVCASLLVVMREAMEECVRRGVPKEAARDFL
                     LGHMNVLGAVIFEETPGVFSDACNKAIEFGKPMLMREDWKRVFEPQEIADSIRRIT"
     misc_feature    complement(217518..217793)
                     /locus_tag="Smed_3771"
                     /note="NADP oxidoreductase coenzyme F420-dependent;
                     Region: F420_oxidored; pfam03807"
                     /db_xref="CDD:202773"
     gene            217969..218574
                     /locus_tag="Smed_3772"
                     /db_xref="GeneID:5318220"
     CDS             217969..218574
                     /locus_tag="Smed_3772"
                     /note="PFAM: regulatory protein TetR;
                     KEGG: sme:SMb20347 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_001312518.1"
                     /db_xref="GI:150375922"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="GeneID:5318220"
                     /translation="MSDLTDSIDATRQENVTRILDAAERLFRHYGYAKTNVADIAREL
                     DMSPANIYRFFASKTEIHQALCSRMLGASYQQAHDIAYLPLSASERLRRYAQGQHKLT
                     VETMLDEKKVHEMVVVAIEHNWHVIEKHISRLDDLLAGIIREGIEAGEFVDTDPAVAA
                     RCFGASLVTLCHPQIVAQCLAKENRATPEELIEFAIRALRK"
     misc_feature    217996..218571
                     /locus_tag="Smed_3772"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    218023..218163
                     /locus_tag="Smed_3772"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:201228"
     gene            218670..219824
                     /locus_tag="Smed_3773"
                     /db_xref="GeneID:5318221"
     CDS             218670..219824
                     /locus_tag="Smed_3773"
                     /note="TIGRFAM: efflux transporter, RND family, MFP
                     subunit;
                     PFAM: secretion protein HlyD family protein;
                     KEGG: sme:SMb20346 putative efflux protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RND family efflux transporter MFP subunit"
                     /protein_id="YP_001312519.1"
                     /db_xref="GI:150375923"
                     /db_xref="InterPro:IPR006143"
                     /db_xref="GeneID:5318221"
                     /translation="MSSRSALNRPSVSSLLSLILLGAVLSGCTEEKAETKEVIRPVKV
                     VEIAAAGKPRELHYSGSVRARTEMNLGFRVGGKITERLVNIGDRVEPGDVLVRVDATD
                     YQLAVRSAEASLLAAEKQVQTTGLAKLRAEQLFNKSFSSQAQLDQATLLYDQAVSTRD
                     AAASSLSQAKNQVNYTDLKADQNGIVTDVNADIGQVVGTGTPVVTVAVDGEKEVEVAV
                     PEIDIAEFRPGKPVQARFWSDDMLVLDGHVREVSGSADPRSRTFSVRVGLPKDERVLL
                     GMTATVEATAGSSAPLFSIPLSALSKKDGQNIVWIVDRDFSTVHARPVKLADFADNGV
                     RVVEGLGAGDLVVAAGTQFMAEDLKVRLQADEQQSAEQQSARAETPELLR"
     sig_peptide     218670..218753
                     /locus_tag="Smed_3773"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.979) with cleavage site probability 0.420 at
                     residue 28"
     misc_feature    218793..219752
                     /locus_tag="Smed_3773"
                     /note="RND family efflux transporter, MFP subunit; Region:
                     RND_mfp; TIGR01730"
                     /db_xref="CDD:233547"
     misc_feature    218889..219011
                     /locus_tag="Smed_3773"
                     /note="Biotin-lipoyl like; Region: Biotin_lipoyl_2;
                     pfam13533"
                     /db_xref="CDD:205711"
     misc_feature    219201..219497
                     /locus_tag="Smed_3773"
                     /note="HlyD family secretion protein; Region: HlyD_3;
                     pfam13437"
                     /db_xref="CDD:222128"
     gene            219853..223005
                     /locus_tag="Smed_3774"
                     /db_xref="GeneID:5318222"
     CDS             219853..223005
                     /locus_tag="Smed_3774"
                     /note="PFAM: acriflavin resistance protein;
                     KEGG: sme:SMb20345 putative efflux protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acriflavin resistance protein"
                     /protein_id="YP_001312520.1"
                     /db_xref="GI:150375924"
                     /db_xref="InterPro:IPR001036"
                     /db_xref="GeneID:5318222"
                     /translation="MQASTEDRKPFNLSRWAIGHPSIARFLLALIIITGALGLLRMGQ
                     REDPEFTFRVMVVQAVWPGASIQEMEDQVVNKIERKLQETPHLDFVRSYTRAGSAIIT
                     VQIEGDTNADEVADAFYQVRKKVGDIANELPEGVLGPYFNDEFGDTFITLHSISGDGF
                     SYPELRRFAIEGRDMLLTTPGVEKVVILGDQPEKIFIDVSSKALAERGLTLNDLRDAI
                     AGQNNVDHAGSIDTGTRSVRISVEGGVTKAEDIRELRLRAGERTIRLGDIATVTSGLE
                     DPYSRKFRFNGHDSVQIGVVMAKGFNVTDVGKAVEATYDRFESALPYGVSVDQVSNQP
                     EVVTEAISEFSHALVEALIIVLVVSFLSIGWRSGLVIAIAIPLVLAATFAIMYELGID
                     LQRISLGALIIALGLLVDDAMIVVEMMERKLEEGLEKIDAASFAYSSTAFPMLTGTLI
                     TTAGFIPVGFAQSTAGEYVRSLFYVVGIALVVSWFVAVYFTPWLGYMILKQRHHAGTH
                     HDVFDTRFYRRLRSTVGWAVRHRITVLLMTLAIFMTSLWGFQFIPKNFFPQSSRPEIL
                     VDLWLPEGTSIKEVEKQAKALEQRLMDDKDKRFIATYIGEGAPRFFLPLDQQLRNPNF
                     AQLLVMAKDEPARERLIGKLRTVLAEEFPSIRTKVDRLFLGPPTGWPVQMRVMGPDRE
                     EVRRIANEVKAKFRENPLLGAIHDDWLEPVPAMKLVIDQDRARALGITSQRIRQMLQA
                     AMSGVPLDSFRDGEEAVSIVAREPGGNRHLLSAVQSVYVPTDFGGFVPVSQVAKVVPV
                     MEQGVEWRRDRLPTITVRATLPDGVQSNDVAMKLFDELRGLRDSLPPAYKVEIQGGAE
                     DSAESQASIAAKAPIMLVVIVILLMVQLQHFGKAMLVLATGPLGIIGAAAALLISGAP
                     FGFVAILGVIALLGIIIRNSIILVDQIDQDIAAGMERYEAIIGAAVRRFRPITLTALT
                     AVLALIPISRGVFWGPLAYAMMGGILVATVLTIVVLPAAYALFFGKEPKARKTAPGPA
                     AAQGDADEDSTPYPAPLAAE"
     misc_feature    219886..222906
                     /locus_tag="Smed_3774"
                     /note="Cation/multidrug efflux pump [Defense mechanisms];
                     Region: AcrB; COG0841"
                     /db_xref="CDD:223911"
     gene            223134..224090
                     /locus_tag="Smed_3775"
                     /db_xref="GeneID:5318223"
     CDS             223134..224090
                     /locus_tag="Smed_3775"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type; AraC-type transcriptional regulator domain
                     protein;
                     KEGG: sme:SMb20344 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC-like transcriptional regulator"
                     /protein_id="YP_001312521.1"
                     /db_xref="GI:150375925"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="InterPro:IPR009594"
                     /db_xref="GeneID:5318223"
                     /translation="MSTIMFPQRNLREETAPLRAQILDRLSKLPWDGLSFEHPIPGLS
                     LYRIIQPAGPFSSVYEPSLSFIIKGSKNVRVGNETMVYDEGCFFLTAIGLPVTGQICA
                     ASEREPYVAAALRLDMEKVRRIIADHDIHPTDLPERDLGVAVGTATCELFDALFRLIS
                     LAGAPADIPFLAGHIQNEIIYRLLTGEQGARLRRFALAGTNSNRVAKAVAWLKENYTK
                     QLRVEELAEIANMGVSTLHHHFRAMTAMSPLQFQKHLRLHHARELMLSQSLDAATAAL
                     RVGYESPTQFNREYRRAFGHPPLRDIRAILNSNDSTRRSPAG"
     misc_feature    223248..223709
                     /locus_tag="Smed_3775"
                     /note="AraC-type transcriptional regulator N-terminus;
                     Region: AraC_N; pfam06719"
                     /db_xref="CDD:219148"
     misc_feature    223683..224063
                     /locus_tag="Smed_3775"
                     /note="AraC-type DNA-binding domain-containing proteins
                     [Transcription]; Region: AraC; COG2207"
                     /db_xref="CDD:225117"
     misc_feature    223767..223892
                     /locus_tag="Smed_3775"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     gene            224382..224840
                     /locus_tag="Smed_3776"
                     /db_xref="GeneID:5318224"
     CDS             224382..224840
                     /locus_tag="Smed_3776"
                     /note="PFAM: ferredoxin; [2Fe-2S]-binding domain protein;
                     KEGG: sme:SMb20343 isoquinoline 1-oxidoreductase, alpha
                     ubunit"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="YP_001312522.1"
                     /db_xref="GI:150375926"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR002888"
                     /db_xref="InterPro:IPR006058"
                     /db_xref="GeneID:5318224"
                     /translation="MVNIKINGVEHAIEAEADMPLLWAIRDLVGLTGTKFGCGMAQCG
                     ACTVYVDGSPTRSCQTFIGDIDGAEVTTIEGLKGKVAETVQSVWAELDVPQCGYCQSG
                     QIMSATDLLASNPKPTDTDIDAAMSGNLCRCATYHRIRAGIHEAAKRLEA"
     misc_feature    224382..224837
                     /locus_tag="Smed_3776"
                     /note="Aerobic-type carbon monoxide dehydrogenase, small
                     subunit CoxS/CutS homologs [Energy production and
                     conversion]; Region: CoxS; COG2080"
                     /db_xref="CDD:224991"
     misc_feature    224385..>224588
                     /locus_tag="Smed_3776"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    order(224481..224486,224493..224495,224502..224504,
                     224508..224519)
                     /locus_tag="Smed_3776"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    order(224493..224495,224508..224510,224517..224519)
                     /locus_tag="Smed_3776"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     misc_feature    224595..224816
                     /locus_tag="Smed_3776"
                     /note="[2Fe-2S] binding domain; Region: Fer2_2; pfam01799"
                     /db_xref="CDD:201981"
     gene            224842..227052
                     /locus_tag="Smed_3777"
                     /db_xref="GeneID:5318225"
     CDS             224842..227052
                     /locus_tag="Smed_3777"
                     /note="PFAM: aldehyde oxidase and xanthine dehydrogenase
                     molybdopterin binding;
                     KEGG: sme:SMb20342 putative soquinoline 1-oxidoreductase
                     beta subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidase and xanthine dehydrogenase
                     molybdopterin binding protein"
                     /protein_id="YP_001312523.1"
                     /db_xref="GI:150375927"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="InterPro:IPR008274"
                     /db_xref="GeneID:5318225"
                     /translation="MIPKLMQSMALPARVEASRRQFLLGALAAGTGIAVGYRLLSASP
                     ALAGEAQAGNDSHAFSPYLTIGGDGKVTILSSQFEMGQGSYNGIATLVAEELDADWST
                     IDVKGAAGNIPAYGNIAFGGTMQGTGGSTSMSTSWERYRKAGAAARAMLIAAAAAEWK
                     VDAAEITVENGVLSHPSGKSGGFGAYAAKATTMPVPADVKLKEPSAWKFIGNAELKRF
                     DSARKANGTEQYTIDVKLPGMLTAVMIHPPLFGAKAKSFDASAARAIKGVVDVVETPR
                     GIAVVGEHMWAAIKGREAVTVEWDESGAEKRGTAELMSTYRDLAGKTPAAFARKDGDA
                     EAAFAAAAKVIEATFEFPYLAHAALEPLNAVARRNEDGTIEIWGGHQLPDVYQKLASE
                     IAGVPVENVRLNVMKTGGSFGRRAVFDGDVVVEAVHVAKALGFRAPVKVQWTREEDTR
                     AGRYRPAYVHRLKAGIDADGKLVAWSDHIVGQSIVAKTAWDGMVQNGVDPTSVEGANN
                     LPYAIQNQTVGLTTTDVRVPVLWWRSVGSTHTAFAAEAFLDEVAQAAGRDPLEFRLSM
                     LEPQSRHATVLKLAAEKAEWQKPLPEGRFRGVAVAESFGSVVAQIAEVSTDGNGIKVE
                     RVVAAVDCGLAINPDQVRAQVEGGIGFGLSAILGEEITLTDGKVDQGNFDMYTPLRID
                     AMPKVEVHIVASSNPPSGIGEPGVPPIGPAVANAAFKALGKRIRVMPFAKSLNA"
     sig_peptide     224842..224985
                     /locus_tag="Smed_3777"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.936) with cleavage site probability 0.927 at
                     residue 48"
     misc_feature    224941..227031
                     /locus_tag="Smed_3777"
                     /note="Aerobic-type carbon monoxide dehydrogenase, large
                     subunit CoxL/CutL homologs [Energy production and
                     conversion]; Region: CoxL; COG1529"
                     /db_xref="CDD:224446"
     misc_feature    225517..225744
                     /locus_tag="Smed_3777"
                     /note="Aldehyde oxidase and xanthine dehydrogenase, a/b
                     hammerhead domain; Region: Ald_Xan_dh_C; smart01008"
                     /db_xref="CDD:214971"
     misc_feature    225793..>226530
                     /locus_tag="Smed_3777"
                     /note="Molybdopterin-binding domain of aldehyde
                     dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738"
                     /db_xref="CDD:217210"
     misc_feature    <226666..226869
                     /locus_tag="Smed_3777"
                     /note="Molybdopterin-binding domain of aldehyde
                     dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738"
                     /db_xref="CDD:217210"
     gene            complement(227606..227779)
                     /locus_tag="Smed_3778"
                     /db_xref="GeneID:5318226"
     CDS             complement(227606..227779)
                     /locus_tag="Smed_3778"
                     /note="KEGG: sme:SMb20341 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312524.1"
                     /db_xref="GI:150375928"
                     /db_xref="GeneID:5318226"
                     /translation="MITDEQIRRMGVLLDPQRVEEFAMRRGLHHHPTVDLIVFIAAVG
                     LVSAIMIASLFFG"
     misc_feature    complement(<227687..227749)
                     /locus_tag="Smed_3778"
                     /note="RPAP1-like, C-terminal; Region: RPAP1_C; pfam08620"
                     /db_xref="CDD:192098"
     gene            complement(227812..228009)
                     /locus_tag="Smed_3779"
                     /db_xref="GeneID:5318227"
     CDS             complement(227812..228009)
                     /locus_tag="Smed_3779"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312525.1"
                     /db_xref="GI:150375929"
                     /db_xref="GeneID:5318227"
                     /translation="MSTSKKTPASIRQGGPGASHENAKAPLEIPKPPADSERRTRSKV
                     SGGGGEPDRHHSHDARRKGGH"
     gene            complement(228020..228199)
                     /locus_tag="Smed_3780"
                     /db_xref="GeneID:5317948"
     CDS             complement(228020..228199)
                     /locus_tag="Smed_3780"
                     /note="KEGG: sme:SMb20340 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312526.1"
                     /db_xref="GI:150375930"
                     /db_xref="GeneID:5317948"
                     /translation="MSSRPPPIPAENRSDKGTGEPGTVSTDAKKPDTAENPEKKGQQG
                     NTKVNTTHQGYQQDR"
     gene            complement(228249..228740)
                     /locus_tag="Smed_3781"
                     /db_xref="GeneID:5317949"
     CDS             complement(228249..228740)
                     /locus_tag="Smed_3781"
                     /note="KEGG: sme:SMb20339 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312527.1"
                     /db_xref="GI:150375931"
                     /db_xref="GeneID:5317949"
                     /translation="MPRGSLIAISGICAGLAAVAVLTVSAERRNRSPWRPINATSHWI
                     YGRRAGSVSRLDLAHTGTGFATHMLASFWWALPFAAMLGRNARPSPPRAIAAAAGTTV
                     LAAVVDYGLVPKRLTPGWELALPKSDLAMTYIAMGLGLAFGATLHSAAIATRPGTSRG
                     LIG"
     sig_peptide     complement(228678..228740)
                     /locus_tag="Smed_3781"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.994) with cleavage site probability 0.452 at
                     residue 21"
     gene            complement(228829..230046)
                     /locus_tag="Smed_3782"
                     /db_xref="GeneID:5317950"
     CDS             complement(228829..230046)
                     /locus_tag="Smed_3782"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: sme:SMb20338 putative efflux protein"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001312528.1"
                     /db_xref="GI:150375932"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5317950"
                     /translation="MSNPYGEIFRAPGAKGFSAAGFFARLPIAMAPIGIVAMVSQTHG
                     EYWLAGAVSATFALTNALVAPQISRLVDRVGQTAVVVPTTIVSVAAFLALIIAANRDW
                     AAWTLFVLAFLAAAMPSMPALVRARWTEIFRNRPELNTAFAFESSADELVYISGASLS
                     VGLAVALFPEAGMLTSTIFLALGTAAFILQRSTEPKVHPIEASASQASAIRQRPVQII
                     TLALIFVGSIFATAEVSVVAITKELGQPQAASLVIGVYAVGSFLVGLALGALNPTMPL
                     QRQLLIAVSVIAITSLPLLVADTVPFLAFAVFVSGIAISPTFITAFGLIERRVPESML
                     TEGVTWVMTGIGIGMALGAFVSGWVVDNYGAQKGFWVSVAAGAATVVTVAAGQRSLAG
                     SKAMPAAVPLPAE"
     misc_feature    complement(228988..229962)
                     /locus_tag="Smed_3782"
                     /note="Major Facilitator Superfamily; Region: MFS_1;
                     pfam07690"
                     /db_xref="CDD:219516"
     misc_feature    complement(228934..229944)
                     /locus_tag="Smed_3782"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(order(229000..229002,229009..229014,
                     229021..229026,229033..229038,229069..229071,
                     229078..229083,229093..229095,229102..229107,
                     229114..229116,229255..229257,229267..229269,
                     229276..229278,229288..229290,229300..229302,
                     229336..229338,229345..229350,229357..229362,
                     229369..229371,229588..229590,229606..229611,
                     229618..229623,229657..229659,229666..229671,
                     229678..229683,229690..229695,229843..229848,
                     229852..229857,229867..229869,229876..229881,
                     229888..229890,229939..229944))
                     /locus_tag="Smed_3782"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            230160..230753
                     /locus_tag="Smed_3783"
                     /db_xref="GeneID:5317951"
     CDS             230160..230753
                     /locus_tag="Smed_3783"
                     /note="PFAM: regulatory protein TetR;
                     KEGG: sme:SMb20337 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_001312529.1"
                     /db_xref="GI:150375933"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="GeneID:5317951"
                     /translation="MNKQRKEMIAETRAKLIAAARHAFGTVGYADSSMDDFTGEAGLT
                     RGALYHHFGDKKGLLQAVIREIDAEMTARLNKVSSEAPTRWQGFVDECVAYIRMALEP
                     QIQRIMFRDGPAVLGDISQWPMTQGCITALAGSLDRLKAEGVVIDIDTEAAARLINGA
                     SSQAALWIANSDDPQETSQKAVDGFQALLEGLRVKRD"
     misc_feature    230160..230750
                     /locus_tag="Smed_3783"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    230205..230345
                     /locus_tag="Smed_3783"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:201228"
     gene            complement(230840..231637)
                     /locus_tag="Smed_3784"
                     /db_xref="GeneID:5317952"
     CDS             complement(230840..231637)
                     /locus_tag="Smed_3784"
                     /note="KEGG: sme:SMb20336 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312530.1"
                     /db_xref="GI:150375934"
                     /db_xref="InterPro:IPR000194"
                     /db_xref="GeneID:5317952"
                     /translation="MTSGFIRTLALAGTCLLAGGATAADIYSPVAPETQQVTTESGWT
                     FSFSPYFWAAGLSGDIEQFGLPAVDVDASFSDVFDHLDFALMATAEARNGPYSIFGDA
                     IYIKLSGEGGTPRGIIADDVKLSTETFTGTLGAGYAIYEDSAARLDIVGGLRVWSVES
                     ELSFSGGILPPGGVSRSDDATWVDGIAGFRGTYSFTPEVYLTGWGLVGAGGADLDWDV
                     AAAIGYRFSDTISALAGYRALGVDYSNDGFVFDVVEQGPILGLVVRF"
     sig_peptide     complement(231566..231637)
                     /locus_tag="Smed_3784"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.990 at
                     residue 24"
     gene            complement(231748..233016)
                     /locus_tag="Smed_3785"
                     /db_xref="GeneID:5317953"
     CDS             complement(231748..233016)
                     /locus_tag="Smed_3785"
                     /note="PFAM: protein of unknown function DUF900 hydrolase
                     family protein;
                     KEGG: sme:SMb20335 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312531.1"
                     /db_xref="GI:150375935"
                     /db_xref="InterPro:IPR010297"
                     /db_xref="GeneID:5317953"
                     /translation="MGNVNSCGGRLRVAKTGSTTVSALVALVLLAGCGGHAKGVMAPV
                     ALAQPSATSQVDMLVATTREPSGDAATLFSGERSPTLSMTDVAVSIPPDSRRKPGTVQ
                     WPRKLPPNPETDFAVTRVRKLASNDEARDWFQVHNEGGHVLLFVHGFNNRYEDAVFRL
                     AQIVHDSGAQATPILFTWPSRARLFDYNYDKESTNYSRTALEDTLRTLASAPRVKDIT
                     ILAHSMGTWLTMESLRQMGIRDGGIAPKIENVILASPDIDLDVFAKQWVDMGKARPKF
                     TIFVSQDDRALAVSRLISGDVSRLGAIDPTAEPYRTQLETAGITAIDLTKVQTDDGLH
                     HGKFAESPEIVQLIGQRIIKGQTLTDSDISLGEGITAVVAGTAKNVGTVAAATITAPV
                     TIIEQRGTPRKKVNLEETLTSSENAGNTAR"
     misc_feature    complement(231880..232923)
                     /locus_tag="Smed_3785"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4782"
                     /db_xref="CDD:227121"
     gene            complement(233292..235013)
                     /locus_tag="Smed_3786"
                     /db_xref="GeneID:5317954"
     CDS             complement(233292..235013)
                     /locus_tag="Smed_3786"
                     /note="TIGRFAM: outer membrane autotransporter barrel
                     domain;
                     PFAM: Autotransporter beta- domain protein;
                     KEGG: sit:TM1040_3285 outer membrane autotransporter
                     barrel"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane autotransporter"
                     /protein_id="YP_001312532.1"
                     /db_xref="GI:150375936"
                     /db_xref="InterPro:IPR005546"
                     /db_xref="InterPro:IPR006315"
                     /db_xref="GeneID:5317954"
                     /translation="MVVAKVRKCFSTVLSGALLAGLFCIVGSGEASAANCSAGGGLAY
                     LGNTRGAARSVWLSGTSAGSFGLEAAQGNQMVDTWSKSKRGLHLSLSPVVSNGNGGTH
                     KLLDLSGGKPCLLDTQNQVRDFIPPDFTWPQGRPDIGPIRFFDFDLPEGRPDTGPIRV
                     FPDFDRPAGRPDTGPIRVFPGFDRPDGRPDTEPVRVFPGFDRPDERPDNDLPRIPPDR
                     PDGRPDNDLPRVFPGFDPPSPSPNPTAVRGGRVVGARTAQNCIDPRSVGSDQRRDVPI
                     CPEFVAEEAATQGAGQSRGVPLTPGRDLPAPSLWNFWSDIRFTDISDERYDRDSDTFA
                     RTLDMGLDRRITDDLVVGMSFSLQDSSTHAFHDSLDIDSDGFSFGPYAAYRLSKHWAI
                     DASLTYGRYNNDVELSVLSGKYDSERFAGEISLNGQYKFDAYYVRPKASVTLSHVKSD
                     AYGLSGSLFNFPVSVSLPGDSYNYGVLDMSTEVSRFFRLPDGQPFLVFAELGAQYEFE
                     RPNDGKILTGDLSEVSPSPWAFSLRSGLRMLLNENLQIEATGGYLSLGQDDLDVWEGK
                     LHVSWSF"
     sig_peptide     complement(234912..235013)
                     /locus_tag="Smed_3786"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.997) with cleavage site probability 0.837 at
                     residue 34"
     misc_feature    complement(233343..233996)
                     /locus_tag="Smed_3786"
                     /note="Autotransporter beta-domain; Region:
                     Autotransporter; pfam03797"
                     /db_xref="CDD:217734"
     gene            complement(235031..235990)
                     /locus_tag="Smed_3787"
                     /db_xref="GeneID:5317955"
     CDS             complement(235031..235990)
                     /locus_tag="Smed_3787"
                     /note="PFAM: protein of unknown function DUF323;
                     KEGG: sme:SMb20334 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312533.1"
                     /db_xref="GI:150375937"
                     /db_xref="InterPro:IPR005532"
                     /db_xref="GeneID:5317955"
                     /translation="MKASLNSVVELEPAAEMVWVPGATFMMGSNDHYPEEAPAHPVTV
                     DGFWIDEAPVTNRQFLEFVNATGHVTFAEKKPRAEDYPGAPPSNLRAGSLVFTPPKRP
                     LQGNDISQWWIFTLGANWRHPLGRKSSIGAILDHPVVHIAYDDAKAYAEWAGKELPTE
                     AEWELAARGDLDEAEFAWGDELVPDGKHMANTWQGRFPIENAMEDGFARTSPVRFYPP
                     NGYGLYDMIGNVWEWTTDYWSVRHPEAAAKPCCIPSNPRNADVEASVDPAAGVKVPRR
                     VLKGGSHLCAPNYCRRYRPAARHAQEIDTTTSHVGFRCIRRVS"
     misc_feature    complement(235043..235954)
                     /locus_tag="Smed_3787"
                     /note="Formylglycine-generating sulfatase enzyme; Region:
                     FGE-sulfatase; pfam03781"
                     /db_xref="CDD:217725"
     misc_feature    complement(235034..235951)
                     /locus_tag="Smed_3787"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG1262"
                     /db_xref="CDD:224182"
     gene            complement(236230..237210)
                     /locus_tag="Smed_3788"
                     /db_xref="GeneID:5317956"
     CDS             complement(236230..237210)
                     /locus_tag="Smed_3788"
                     /note="KEGG: rle:RL2862 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312534.1"
                     /db_xref="GI:150375938"
                     /db_xref="GeneID:5317956"
                     /translation="MTKIIREEIALSFFGMLLLGSAALAPAVLVPAALAQEAGDYAPL
                     AEYAAAEDPPVFDTPEKAVEAFKETVNGGDFDKLAVLLGLDPAKTKSSEGVMETYADI
                     QEGVNEKVAVEDVEGRKVIEIGDERWPFPFPVSKGEDGKWAFDTYVGLEEIANRRVGD
                     NELATIATMRAYVGAQEEYARGDHDGDGVLEYAQKLISEKGAQDGLYWPAEEFGGEES
                     PAAAALAEGDALERAKAGEGFQGYRYRILTGQGDNIAGGKFDYIINGNMIAGFGLVAW
                     PVRYGVTGVKTFVVNRNGIVYEADLGGDTEKTAVDIRTFNPGDQWMVVPD"
     sig_peptide     complement(237103..237210)
                     /locus_tag="Smed_3788"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.997 at
                     residue 36"
     misc_feature    complement(236239..237054)
                     /locus_tag="Smed_3788"
                     /note="Protein of unknown function (DUF2950); Region:
                     DUF2950; pfam11453"
                     /db_xref="CDD:221113"
     gene            complement(237229..238608)
                     /locus_tag="Smed_3789"
                     /db_xref="GeneID:5317990"
     CDS             complement(237229..238608)
                     /locus_tag="Smed_3789"
                     /note="KEGG: sme:SMa0690 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312535.1"
                     /db_xref="GI:150375939"
                     /db_xref="GeneID:5317990"
                     /translation="MPTELLRLIARPIGVAGLAILMAAGPTLVPRGLAQQAAQGQTGA
                     TGDEQADLLTEEELETMVARIALYPDELVALVSSASLYPLQIVEAARFLEEKKTNKDL
                     QPKDSWDDSVISLLNYPEIVKMMSDDLDWTQALGSALAYQQKDVLIAVQTLRDKAVAD
                     GVIKNDDKLKVVNEGDNIVIQAADPEKIYVPRYEPEMLYEPGYAPAPVAYYPDPYPSY
                     YYPSAPYFAAAITGAAIWAAAVDWDDWGVWGGHWDSDVDIDCDNCFNNIDVDRDKFKM
                     NDVDWKNVDRSKIKFDKNQLANIDRDKFKNDFKANRGNNIANRARDVRRDHGDIARRP
                     GKVSVDDIRKSKVDASRVRAERNRPQNTQRRVEAPRRDGGAAVNRARASTGKATGARP
                     KVHPKAHAPRPGAHVRHSSGGKHSALGKVGNKRQTHISSSRGHHSMGGGHRGGGGHKA
                     VKRGGGRRR"
     sig_peptide     complement(238504..238608)
                     /locus_tag="Smed_3789"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.668) with cleavage site probability 0.397 at
                     residue 35"
     misc_feature    complement(<238009..238452)
                     /locus_tag="Smed_3789"
                     /note="Protein of unknown function (DUF3300); Region:
                     DUF3300; pfam11737"
                     /db_xref="CDD:221195"
     gene            complement(238766..239635)
                     /locus_tag="Smed_3790"
                     /db_xref="GeneID:5317991"
     CDS             complement(238766..239635)
                     /locus_tag="Smed_3790"
                     /note="KEGG: rle:pRL110217 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312536.1"
                     /db_xref="GI:150375940"
                     /db_xref="GeneID:5317991"
                     /translation="MDYPGCLRSGLPGSGRKAVTPGLGWRYAAAFVVATAAACGAAEA
                     QDASGENLAKQLSNPVASLISVPFQLNYDRGFGPDDGHRVTLNIQPVIPISLNEDWNL
                     ISRTILPVISQSDVAGPSGDQFGLGDTVQSFFFSPKDPTAGGIIWGFGPVFLLPTGTD
                     DLLGSKKWGVGPTAVALKQDGPWTYGALVNHIWSFAGNEDRADVNSTFLQPFISYTTP
                     DAWTFAVNTESTYDWESDEWSVPVNFQVSKLVKFGEQPVSITAGARYWAAAPDNGPQG
                     WGARLAVTFLFPK"
     gene            239958..241604
                     /locus_tag="Smed_3791"
                     /db_xref="GeneID:5317992"
     CDS             239958..241604
                     /locus_tag="Smed_3791"
                     /note="PFAM: sulfatase;
                     KEGG: rba:RB3877 aryl-sulfate sulphohydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="YP_001312537.1"
                     /db_xref="GI:150375941"
                     /db_xref="InterPro:IPR000917"
                     /db_xref="GeneID:5317992"
                     /translation="MKKEPIADQRDPRERANITRRSILLGGTAIAAASTVLTTGGAQT
                     AQAQTQTQAPDAGGSAKQPNILVIWGDDIGTWNISHNNRGMMGYKTPNIDRIAQEGLS
                     FTDYYGQQSCTAGRAAFIGGNVPVRTGMTKVGLPGAKEGWQETDVTMATVLKSQGYAT
                     GQFGKNHQGDRDEHLPTNHGFDEFFGNLYHLNAEEEPENRDYPKDPEFRRRFGPRGVI
                     HSFADGKIEDTGALTKKRMETIDEESLAAAKDFITRQNQAGTPFFVWWNGTRMHFRTH
                     VKAEHAGISGPSGDEYHDGMVEHDMHVGELLKLLDELGIAENTVVMYSTDNGPHFNTW
                     PDAATTPFRSEKNSNWEGAYRVPAFVRWPARFPAGKTLNGIVAHEDWLPTFGAIAGAP
                     DVKEKLLEGVELNGRRYRNYIDGYNQLEYLEGKTDQSPRHEFWYVNDDGQVVAARYDD
                     WKVVFLENRGEAFGVWREPFTELRVPLLFNLRRDPFEKAQHNANTYDDWFLERAFVVV
                     PIQGLAAKFLQTMKEYPPSQSPGSFNLTKIEESLKAGMRN"
     sig_peptide     239958..240101
                     /locus_tag="Smed_3791"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.998) with cleavage site probability 0.978 at
                     residue 48"
     misc_feature    240132..241427
                     /locus_tag="Smed_3791"
                     /note="Arylsulfatase A and related enzymes [Inorganic ion
                     transport and metabolism]; Region: AslA; COG3119"
                     /db_xref="CDD:225661"
     misc_feature    240144..241169
                     /locus_tag="Smed_3791"
                     /note="Sulfatase; Region: Sulfatase; pfam00884"
                     /db_xref="CDD:216172"
     gene            241865..242869
                     /locus_tag="Smed_3792"
                     /db_xref="GeneID:5317993"
     CDS             241865..242869
                     /locus_tag="Smed_3792"
                     /note="KEGG: bja:bll4740 nonspecific acid phosphatase
                     precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="nonspecific acid phosphatase"
                     /protein_id="YP_001312538.1"
                     /db_xref="GI:150375942"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5317993"
                     /translation="MFQVTRRSAMKIAALAAAASSMGQAAFAAEPSILPSWVDGDAKA
                     RIIDFVSATTTEGGPDFVEPADRVAVFDNDGTLWGEQPMYVQLAFALDRVKQLAPQHS
                     EWQTTEPFKSVLAGDMAGVAASGERGLIELVAATHAGMSTEEFERIVSDWMESARHPA
                     SGKPYTAHIFKPMVELIDYLKSNQFEVFIVSGGGVEFMRPWTERVYGIPPQNVVGSSI
                     KTRYELRDGVPAIMRLPEIDFIDDGLGKPVGINKFIGRRPIAAFGNSDGDFEMLEWTT
                     AGPGRRFGLIVHHDDAEREKAYDRDSHFGRLARGLDEAPARGWTVVSIKDDWKLVYPE
                     "
     sig_peptide     241865..241951
                     /locus_tag="Smed_3792"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 29"
     misc_feature    242069..242755
                     /locus_tag="Smed_3792"
                     /note="Phosphoserine phosphatase [Amino acid transport and
                     metabolism]; Region: SerB; COG0560"
                     /db_xref="CDD:223634"
     misc_feature    <242423..242683
                     /locus_tag="Smed_3792"
                     /note="haloacid dehalogenase-like hydrolase; Region: HAD;
                     pfam12710"
                     /db_xref="CDD:221729"
     gene            complement(242993..243394)
                     /locus_tag="Smed_3793"
                     /db_xref="GeneID:5317994"
     CDS             complement(242993..243394)
                     /locus_tag="Smed_3793"
                     /note="PFAM: response regulator receiver;
                     KEGG: bch:Bcen2424_3199 two component transcriptional
                     regulator, LuxR family"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver protein"
                     /protein_id="YP_001312539.1"
                     /db_xref="GI:150375943"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="GeneID:5317994"
                     /translation="MSESQRIIAIVDDDELVRRALCRLVQSLSLKPVAYASGELFLKE
                     LEQTSPSCVLLDFHMPNMNGLDVLHELSARRARLAVIVITGADEEGVRESCMRAGASG
                     FLNKPLSRDTLSSAIEALRGDQRPAKAPRSQ"
     misc_feature    complement(243041..243373)
                     /locus_tag="Smed_3793"
                     /note="Response regulator receiver domain; Region:
                     Response_reg; pfam00072"
                     /db_xref="CDD:200976"
     misc_feature    complement(243035..243367)
                     /locus_tag="Smed_3793"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(243074..243079,243086..243088,
                     243143..243145,243203..243205,243227..243229,
                     243356..243361))
                     /locus_tag="Smed_3793"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(243227..243229)
                     /locus_tag="Smed_3793"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(243203..243211,243215..243220))
                     /locus_tag="Smed_3793"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(243071..243079)
                     /locus_tag="Smed_3793"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     gene            complement(243421..244068)
                     /locus_tag="Smed_3794"
                     /db_xref="GeneID:5317995"
     CDS             complement(243421..244068)
                     /locus_tag="Smed_3794"
                     /note="PFAM: regulatory protein LuxR; response regulator
                     receiver;
                     KEGG: bja:blr4774 two-component response regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver protein"
                     /protein_id="YP_001312540.1"
                     /db_xref="GI:150375944"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="GeneID:5317995"
                     /translation="MRESVGRVLLLDDDELVLRSLKRLLSASGYLVGTYQSASELLAC
                     DDLDTADCIILDLGLPDSDGFHVQEALAAAGGSQSIVFLTGKGDIPASVRAMKAGAVD
                     FLTKPVEAAALLEAVDVALQRARSRRETEEKKANVAMRIDRLTARETQVMHLVVSGLL
                     NKQIAADLGTVEKTIKVHRGRMMSKLGVRTVADLVRLVSGAETMHGGIGPKSNYD"
     misc_feature    complement(243442..244014)
                     /locus_tag="Smed_3794"
                     /note="response regulator FixJ; Provisional; Region: fixJ;
                     PRK09390"
                     /db_xref="CDD:181815"
     misc_feature    complement(243748..244014)
                     /locus_tag="Smed_3794"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(243748..243753,243760..243762,
                     243817..243819,243877..243879,243901..243903))
                     /locus_tag="Smed_3794"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(243901..243903)
                     /locus_tag="Smed_3794"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(243877..243885,243889..243894))
                     /locus_tag="Smed_3794"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(243748..243753)
                     /locus_tag="Smed_3794"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(243475..243639)
                     /locus_tag="Smed_3794"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(243496..243498,243529..243543,
                     243547..243552,243556..243561,243583..243591,
                     243628..243636))
                     /locus_tag="Smed_3794"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(243481..243483,243490..243498,
                     243589..243591,243595..243597,243601..243603))
                     /locus_tag="Smed_3794"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(244078..245910)
                     /locus_tag="Smed_3795"
                     /db_xref="GeneID:5317996"
     CDS             complement(244078..245910)
                     /locus_tag="Smed_3795"
                     /note="PFAM: ATP-binding region ATPase domain protein;
                     histidine kinase A domain protein;
                     KEGG: sme:SMa0939 probable sensor histidine kinase of
                     two-component system"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="YP_001312541.1"
                     /db_xref="GI:150375945"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="GeneID:5317996"
                     /translation="MLRIRPQTVIVTMFALIAGTLVCHATEPRRVLLIYESESTLVAA
                     MQLASGFQEYMEANDPGHVEYYTEYLDTLRFSSPEHSLRLAGFLEAKYRQLNLDVVVA
                     AGPGALRFVLETRERFANDVPVVFGAVTESSVTGNLPPDVKGVVSRFDVGKTVQLASR
                     LQPRARKVVVMYGSAPFDRKWGDTATAVLGERYAGLDVEYVSGLSLDGFRKTAAELPS
                     DAALVILTVFEDAEGMKFVPRDAARAIAAASGAPVYGVYSSYLGFRVLGGYVGTFPSI
                     GAQMAALSLDVMRGDLSAPRTTPAQETALVDWREVQRLGIDDVLIPEDAEILSYAPSV
                     WERYRLPISAALLVIAAQMLTIAALVYQNRRGRRLEATLASERVELAHLSRRSQLGEL
                     SGAFAHELTQPLTSILANAEAGQRLATETAPDMNEIRAIFDDIVADDRRASSVISQLR
                     SMMLKGEASQEILDLNDAVRQTVALAHAEMLARRTEVEVKNELASVRVKANLVQLQQV
                     ILNLLVNAADAMADIPPKQRKVEIAVDRSNNGYCELSVADMGPGIPAGMQGEVFKPFV
                     SSKKGGLGLGLAICRSIVEAQGGKLFFDDGVKRGARAIIILPSA"
     sig_peptide     complement(245833..245910)
                     /locus_tag="Smed_3795"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.998) with cleavage site probability 0.998 at
                     residue 26"
     misc_feature    complement(<245386..245643)
                     /locus_tag="Smed_3795"
                     /note="Type 1 periplasmic binding fold superfamily;
                     Region: Periplasmic_Binding_Protein_Type_1; cl10011"
                     /db_xref="CDD:245225"
     misc_feature    complement(244081..245016)
                     /locus_tag="Smed_3795"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: BaeS; COG0642"
                     /db_xref="CDD:223715"
     misc_feature    complement(244555..244749)
                     /locus_tag="Smed_3795"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    complement(order(244564..244566,244576..244578,
                     244585..244587,244597..244599,244606..244608,
                     244618..244620,244681..244683,244690..244692,
                     244702..244704,244711..244713,244723..244725,
                     244735..244737))
                     /locus_tag="Smed_3795"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    complement(244717..244719)
                     /locus_tag="Smed_3795"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    complement(244090..244365)
                     /locus_tag="Smed_3795"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(244102..244104,244108..244113,
                     244126..244128,244132..244134,244180..244191,
                     244252..244257,244261..244263,244267..244269,
                     244273..244275,244357..244359))
                     /locus_tag="Smed_3795"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(244183..244185,244189..244191,
                     244255..244257,244261..244263))
                     /locus_tag="Smed_3795"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            246187..247404
                     /locus_tag="Smed_3796"
                     /db_xref="GeneID:5317997"
     CDS             246187..247404
                     /locus_tag="Smed_3796"
                     /note="KEGG: rle:RL1907 putative transmembrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane protein"
                     /protein_id="YP_001312542.1"
                     /db_xref="GI:150375946"
                     /db_xref="GeneID:5317997"
                     /translation="MNGASHPSTDNDAVENAPSSGLANFRASHGGPFFELQAQLKLLR
                     ENTLRSGARAILFVALAWGVPFLLGIPRSFSLDHSQNAYLADPGVWAKFFIGIGAFIL
                     AEQQVERGLRTRLSQFIRAPIIAPGAVEEAGRQLSVALRQRDSRGAELICLALAVFAA
                     ALSYFNFHTVDVSSWAVEHRPEGNRITAAGWWSICISLPLFVFLFLRGMWRHFVWANL
                     LRRIAKMDLRLVATHPDGKGGLAFLAQYPNAYVFFVFGMSSAIAAAIAKNILQESLSM
                     TTFSMVMTAWLAIVVAFFAYPLSAFTPPLARLKENGLALLGAQATRYHRAAERKAVGR
                     NIFEDPTPEPADEIADPSKLFEATRKLKTVLVSREAVVPVAAAALIPFAVAGATRLPY
                     KEVFSVMKKLLLL"
     gene            247552..248292
                     /locus_tag="Smed_3797"
                     /db_xref="GeneID:5317998"
     CDS             247552..248292
                     /locus_tag="Smed_3797"
                     /note="PFAM: YidE/YbjL duplication domain protein;
                     KEGG: zmo:ZMO1681 aspartate:alanine antiporter"
                     /codon_start=1
                     /transl_table=11
                     /product="YidE/YbjL domain-containing protein"
                     /protein_id="YP_001312543.1"
                     /db_xref="GI:150375947"
                     /db_xref="InterPro:IPR006512"
                     /db_xref="GeneID:5317998"
                     /translation="MTFIQSLLHQSPEIALFLALAGGYWIGKFQFGKFQLGKFQLGGV
                     AGSLLVAVLISQIGVTIGNGIKAVLFALFIYAVGFESGPQFFRSLGRQSIREIIMAAV
                     LAITGLVTVEWFTGRSIRDDAIKAEAEMLAGASVYGVGEQPALPMLVGRLFSVERAAG
                     RIISELERKGPAATISIERVKRGGKLIGNDPGLVLEKGDILLVVGLLIGLVIRLGSVP
                     LTLGGGGGALLSRLVFGWFRTRNMAIAG"
     misc_feature    247594..>247953
                     /locus_tag="Smed_3797"
                     /note="Predicted Permease Membrane Region; Region:
                     Asp-Al_Ex; cl06061"
                     /db_xref="CDD:244286"
     gene            248423..249394
                     /locus_tag="Smed_3798"
                     /db_xref="GeneID:5317999"
     CDS             248423..249394
                     /locus_tag="Smed_3798"
                     /note="PFAM: ATPase associated with various cellular
                     activities AAA_3; ATPase associated with various cellular
                     activities AAA_5;
                     KEGG: rle:RL1917 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="YP_001312544.1"
                     /db_xref="GI:150375948"
                     /db_xref="InterPro:IPR011703"
                     /db_xref="InterPro:IPR011704"
                     /db_xref="GeneID:5317999"
                     /translation="MGNREDIQALGKRIGQSIIGQEAMIERLLLGLLGNGHLLVEGLP
                     GLAKTRAIKSLAKNLEASLSRIQFTPDLLPSDITGSEVYFSEGGKGEFKFQQGPVFAN
                     LILADEINRAPAKVQSALLEAMEERQVTVGGQSHPLPALFLVMATQNPIEQEGTYPLP
                     EAQLDRFLMHVRVDYPDANSEVAIMELVRSEEREPHAKGAEAQKLAAEVVLAARREIS
                     EIAVSRPVEDYIVALVMATRYPDKIDTELAKWIQVGASPRGVIGLDKVSRAHAWLKGR
                     DFVTPDDVQAIVHDVFRHRLVLSYEAHAGGVTADQAVDRIVEKVATA"
     misc_feature    248432..249385
                     /locus_tag="Smed_3798"
                     /note="MoxR-like ATPases [General function prediction
                     only]; Region: COG0714"
                     /db_xref="CDD:223786"
     misc_feature    248552..248947
                     /locus_tag="Smed_3798"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    order(248552..248572,248741..248743,248864..248866)
                     /locus_tag="Smed_3798"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    248552..248569
                     /locus_tag="Smed_3798"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    248729..248746
                     /locus_tag="Smed_3798"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    248918..248920
                     /locus_tag="Smed_3798"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     gene            249410..250405
                     /locus_tag="Smed_3799"
                     /db_xref="GeneID:5318097"
     CDS             249410..250405
                     /locus_tag="Smed_3799"
                     /note="PFAM: protein of unknown function DUF58;
                     KEGG: rle:RL1916 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312545.1"
                     /db_xref="GI:150375949"
                     /db_xref="InterPro:IPR002881"
                     /db_xref="GeneID:5318097"
                     /translation="MAISLPAFGRTKEILRRAAGASDGAYVSVDNLVALESMAADLTF
                     LRKAPVRRFLAGRHESRMRGRGLSFEELRTYMPGDDIRTIDWRVTARTGQPFVRVYNE
                     EKDRPALVIVDQRTNMFFGSRRSMKSVAAAEAAALCAWRVMALGDRVGGVVFNDLKQE
                     SIRPHRSRGSVIRFAETISLQNKALSAGSDIERAPGQLNAVLGNVAAVAQHDHLIIVI
                     SDFDGHGPETRDLLLRMSVSNDVIAILIYDPFLLDLPRQGDMVVSGGALQAELQFGRS
                     NVRDAVDSFARNRGRELLSWQEEMGLPMLPVSAAEEVAPQLRTLLAQLAWRQRRR"
     misc_feature    249605..249859
                     /locus_tag="Smed_3799"
                     /note="Protein of unknown function DUF58; Region: DUF58;
                     pfam01882"
                     /db_xref="CDD:216761"
     gene            250406..250927
                     /locus_tag="Smed_3800"
                     /db_xref="GeneID:5318098"
     CDS             250406..250927
                     /locus_tag="Smed_3800"
                     /note="KEGG: reh:H16_A1606 hypothetical membrane
                     associated protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312546.1"
                     /db_xref="GI:150375950"
                     /db_xref="GeneID:5318098"
                     /translation="MDPTPAPDPMLAATLRQMADIALPPRVSMLPATWGWAALFGLVA
                     IVLAAVLWHRLRQYKRNRYRREALAELSRFEKEVDQPSGRRHAMQSLPALVKRTALAA
                     WQRETVASLSGKEWSDFLEAHAGRARIDGEAYRFFAESEYRPATLAAMDEATARQRLA
                     SARQWIEGHNVRP"
     misc_feature    250448..250912
                     /locus_tag="Smed_3800"
                     /note="Domain of unknown function (DUF4381); Region:
                     DUF4381; pfam14316"
                     /db_xref="CDD:222674"
     gene            250914..251918
                     /locus_tag="Smed_3801"
                     /db_xref="GeneID:5318099"
     CDS             250914..251918
                     /locus_tag="Smed_3801"
                     /note="PFAM: von Willebrand factor type A;
                     KEGG: reu:Reut_A2888 von Willebrand factor, type A"
                     /codon_start=1
                     /transl_table=11
                     /product="von Willebrand factor type A"
                     /protein_id="YP_001312547.1"
                     /db_xref="GI:150375951"
                     /db_xref="InterPro:IPR002035"
                     /db_xref="GeneID:5318099"
                     /translation="MYVLDHPWLLLLLPAPLFVWWLLPPYREQTPAVRIPFFEDITRA
                     AGIGPTEGSVVPRANLLQKIIAPICWLLVLTALARPQFVEPPIEKTEPQRDLMLALDL
                     SQSMDTRDFSDPQGNLQARVDAVKTVVADFVDRRPYDRLGLVAFGDAPYPLVPFTMDH
                     ATVRSMLTGALPGMAGPKTALGDALGLSIKLFQQSQAPDKVLVVLTDGNDTASKMPPD
                     KAAEIASQNHIRIHTVGIGNPDAQGEEKLDTETLQKIATATGGRYFFGQDQQALAEIY
                     TLLDSITPANQKTLSWRPRIELFHYPLGAAVLLVLGYHALMWLLSVSAARRRNNEAEA
                     "
     misc_feature    251193..251729
                     /locus_tag="Smed_3801"
                     /note="VWA BatA type: Von Willebrand factor type A (vWA)
                     domain was originally found in the blood coagulation
                     protein von Willebrand factor (vWF). Typically, the vWA
                     domain is made up of approximately 200 amino acid residues
                     folded into a classic a/b...; Region: vWA_BatA_type;
                     cd01467"
                     /db_xref="CDD:238744"
     misc_feature    order(251214..251216,251220..251222,251226..251228,
                     251448..251450,251532..251534)
                     /locus_tag="Smed_3801"
                     /note="metal ion-dependent adhesion site (MIDAS); other
                     site"
                     /db_xref="CDD:238744"
     gene            251915..253483
                     /locus_tag="Smed_3802"
                     /db_xref="GeneID:5318100"
     CDS             251915..253483
                     /locus_tag="Smed_3802"
                     /note="PFAM: von Willebrand factor type A;
                     Tetratricopeptide TPR_2 repeat protein;
                     SMART: Tetratricopeptide domain protein;
                     KEGG: rle:RL1913 putative transmembrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312548.1"
                     /db_xref="GI:150375952"
                     /db_xref="InterPro:IPR002035"
                     /db_xref="InterPro:IPR013026"
                     /db_xref="InterPro:IPR013105"
                     /db_xref="GeneID:5318100"
                     /translation="MIADFHFLRPWWLLAVLAAGLLVWLMRRQSDMRSRWKHLIAPNL
                     LDHLLIDRGRQSGFRPVYLVAGLIALSGLAAAGPTWERERPPFVEDTAPLVIAVDLGP
                     TMNATDISPTRLERAKLKVRDIMAKRKGARTALFAYAGSAHMVLPLTEDASLISTYLA
                     ALSPALMPVEGKNTAKALEAAEAALADEPAPGTILFLTDGIEQSAFTAFSQYEGRNDL
                     MVLGIGTEAGGPVKTESGAYLTDGTGARVLARLDVDALQELRSSSSAQVATVTLDDGD
                     VDWIVRRIQTSFAQRTEEGLTRWRDMGWYLTIVVAILVALTFRRGHHVRWLGTVVLIL
                     SFHMPGRAEAADFMDLWLTPDQQGQRAFSRGDYAAAAEHFSDPEWRGVSLYRAGRYQD
                     AIDAFAQSTAPESYFNQGNSLMHLDKPEEAIGAYQQALKQRTGWAEAKTNLALAERRK
                     EEKDKQEDDKQQEAAGLDPDEVQFDDKAKHGKEGEVQTGAQTAEMWMRNIQVSPAALL
                     ARKFAIEASQEDRQ"
     misc_feature    252191..252766
                     /locus_tag="Smed_3802"
                     /note="von Willebrand factor type A domain; Region: VWA_2;
                     pfam13519"
                     /db_xref="CDD:222192"
     misc_feature    order(252209..252211,252446..252448,252509..252511)
                     /locus_tag="Smed_3802"
                     /note="metal ion-dependent adhesion site (MIDAS); other
                     site"
                     /db_xref="CDD:238119"
     misc_feature    252980..253261
                     /locus_tag="Smed_3802"
                     /note="tol-pal system protein YbgF; Region: tol_pal_ybgF;
                     TIGR02795"
                     /db_xref="CDD:188247"
     misc_feature    252980..253207
                     /locus_tag="Smed_3802"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cd00189"
                     /db_xref="CDD:238112"
     misc_feature    order(252980..252982,252989..252994,253055..253060,
                     253067..253072,253133..253138,253145..253150,
                     253157..253162)
                     /locus_tag="Smed_3802"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     misc_feature    order(252986..252988,253022..253024,253034..253036,
                     253055..253057,253091..253093,253103..253105,
                     253112..253114,253142..253144,253178..253180,
                     253190..253192,253199..253201)
                     /locus_tag="Smed_3802"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     gene            253480..254823
                     /locus_tag="Smed_3803"
                     /db_xref="GeneID:5318101"
     CDS             253480..254823
                     /locus_tag="Smed_3803"
                     /note="KEGG: reh:H16_A1609 hypothetical membrane spanning
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312549.1"
                     /db_xref="GI:150375953"
                     /db_xref="GeneID:5318101"
                     /translation="MTIAAPRLYRLLAVLFCWLSTQGPALSADPLARAALQSQGTLYA
                     GQQILVDVDVLVPNYFLQSPQFPAIDIPGAIVTLDDGRALNLNETIDGTPYSGIRRTY
                     IIVPQAAGDFTLPPVPITFGYAAVPPQATRGEVTFPPLRFTVRSAPGTAGDSPGIVAA
                     KVSVSQELDQDPAQLKAGDTMVRTVTVRAEGLRAMMIPEPDFTAPQGVRLYRQDPSLS
                     EETDRNGQSIAGLRKDVASYLFQDAGNYVLPAVTVSWFDPASAKTQSATAPAVSVTVS
                     AAAALSPALAPPAPEPQRDAFDWLHLALIGGIVLLTASSLWVAANGLSRLEAWWQERR
                     SRERQSEPAFFRQVEQACKSGRDDAIARALDAWSRKAGAMPLELWLGRFADAETKQVY
                     QAWQRTRYASQQASQPLGAGLLLPGLKKAREAWLMQETEAPGRKPALLPLNPTMP"
     sig_peptide     253480..253563
                     /locus_tag="Smed_3803"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.998) with cleavage site probability 0.963 at
                     residue 28"
     misc_feature    <253591..>254265
                     /locus_tag="Smed_3803"
                     /note="Oxygen tolerance; Region: BatD; pfam13584"
                     /db_xref="CDD:222242"
     gene            254944..256912
                     /locus_tag="Smed_3804"
                     /pseudo
                     /db_xref="GeneID:5318102"
     gene            complement(257084..258742)
                     /locus_tag="Smed_3805"
                     /db_xref="GeneID:5318103"
     CDS             complement(257084..258742)
                     /locus_tag="Smed_3805"
                     /note="PFAM: sulfatase;
                     KEGG: rba:RB9498 arylsulfatase"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="YP_001312550.1"
                     /db_xref="GI:150375954"
                     /db_xref="InterPro:IPR000917"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5318103"
                     /translation="MSFPDADKRKNAQGSISIDRRSLLLGGTILAAAAAANGAVAVGS
                     AKAQEQSSAGSGKTPNILVIFGDDIGIPQISAYTMGLMGYRTPNIDRIAAEGAIFTDA
                     YGQQSCTAGRASFILGQEPFRTGLLTIGMPGDPHGIQDWMPTIADVMKSKGYATGQFG
                     KNHLGDRDEHLPTNHGFDEFFGNLYHLNAEEEPEGYFYPKDEEFRKNFGPRGVIKSSA
                     DGKIEDTGALNTKRMETVDEEFLAAAKDFIDRQAKADKPFFCWFNSTRMHVFTHLKPE
                     SMGKTGKGIHADGMVEHDGHVGQLLQQLDDLGITENTIVLYTTDNGAELALWPDGAMT
                     MFHGEKGTTWEGGFRIPMMVRWPGVVKPGTQINDPVTLMDWMPTFATAAGIPDVKEEM
                     KTGFKSGDKTFKVHLDGYDLTALLKGEAEEPPREAVYYFDQGGNLNAIRWNDWKLSFA
                     VNSEGNIATATRETPSWANIANLRMDPYERGTKEGGGAMEFIARNMWLLVPIQSKIKE
                     FFQDFDQYPYQPGSTLNASGINYNLLQQQAALKRLGDLERLAPR"
     sig_peptide     complement(258599..258742)
                     /locus_tag="Smed_3805"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.991) with cleavage site probability 0.396 at
                     residue 48"
     misc_feature    complement(257306..258568)
                     /locus_tag="Smed_3805"
                     /note="Arylsulfatase A and related enzymes [Inorganic ion
                     transport and metabolism]; Region: AslA; COG3119"
                     /db_xref="CDD:225661"
     misc_feature    complement(257501..258568)
                     /locus_tag="Smed_3805"
                     /note="Sulfatase; Region: Sulfatase; pfam00884"
                     /db_xref="CDD:216172"
     gene            259169..259525
                     /locus_tag="Smed_3806"
                     /db_xref="GeneID:5318104"
     CDS             259169..259525
                     /locus_tag="Smed_3806"
                     /note="KEGG: sme:SMb20331 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312551.1"
                     /db_xref="GI:150375955"
                     /db_xref="GeneID:5318104"
                     /translation="MPNTLMAGKRSQDWANLVLAACLFVSPWVIGFAADSVPTWNAWI
                     AGIVLGALAVATLSAFAEWEEWANMVIGLWLIVSPWLLGFTGNVNAMWTHVILGVLVA
                     AIAAWAVWDFRHHSHA"
     sig_peptide     259169..259270
                     /locus_tag="Smed_3806"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.719) with cleavage site probability 0.670 at
                     residue 34"
     misc_feature    259202..259351
                     /locus_tag="Smed_3806"
                     /note="SPW repeat; Region: SPW; pfam03779"
                     /db_xref="CDD:202765"
     misc_feature    259358..>259450
                     /locus_tag="Smed_3806"
                     /note="SPW repeat; Region: SPW; pfam03779"
                     /db_xref="CDD:202765"
     gene            complement(259774..260856)
                     /locus_tag="Smed_3807"
                     /db_xref="GeneID:5318105"
     CDS             complement(259774..260856)
                     /locus_tag="Smed_3807"
                     /note="PFAM: oxidoreductase domain protein;
                     KEGG: sme:SMb20330 probable trehalosemaltose utilization
                     protein, function"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain-containing protein"
                     /protein_id="YP_001312552.1"
                     /db_xref="GI:150375956"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="GeneID:5318105"
                     /translation="MRLLILGTGGMANSHAKAFAEIEGVEMVGAVDVDPSRARAFAST
                     HGIERTFTSLDEAIAWGEFDAATNVTPDKAHHPTTLALIAAGKHVLCEKPLAENYEKA
                     AEMAAAAERAGLVTMVNLTYRNVAPLQKARELVVAGEIGLVRHLEASYLQSWLVSKAW
                     GDWASESKWLWRLSTKHGSNGVLGDVGIHILDFAGYGANSSVERVFARLKAFDKAPGN
                     RLGEYDLDANDSFAMTAEFENGAMAVIHASRWATGHLNELRLRLHGDKGALEVIHTPD
                     GSSLRACLGADVEKAVWRTVDAGTVPTNYQRFVEAVKAGRTVEPGFRHAADLQKVLDL
                     AIETERERRELGVPDIDAVVQERAVG"
     misc_feature    complement(259810..260856)
                     /locus_tag="Smed_3807"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:223745"
     misc_feature    complement(<260572..260856)
                     /locus_tag="Smed_3807"
                     /note="Oxidoreductase family, NAD-binding Rossmann fold;
                     Region: GFO_IDH_MocA; pfam01408"
                     /db_xref="CDD:201778"
     sig_peptide     complement(260806..260856)
                     /locus_tag="Smed_3807"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.878) with cleavage site probability 0.521 at
                     residue 17"
     misc_feature    complement(260110..260463)
                     /locus_tag="Smed_3807"
                     /note="Oxidoreductase family, C-terminal alpha/beta
                     domain; Region: GFO_IDH_MocA_C; pfam02894"
                     /db_xref="CDD:217272"
     gene            complement(260868..261761)
                     /locus_tag="Smed_3808"
                     /db_xref="GeneID:5318362"
     CDS             complement(260868..261761)
                     /locus_tag="Smed_3808"
                     /note="PFAM: protein of unknown function DUF1037;
                     KEGG: sme:SMb20329 probable ThuA protein, function"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312553.1"
                     /db_xref="GI:150375957"
                     /db_xref="InterPro:IPR009381"
                     /db_xref="GeneID:5318362"
                     /translation="MAGPRGVYPARLRARRLKSRTAGIRQRVPQTTRRMNLSINAIVW
                     GENIHEQTNAVVREIYPEGMHNTIAAALNSDPGINATTATLQEPEHGLSEARLAAADV
                     LLWWGHKDHGAVDDAIVERVAKRVWEGMGLIVLHSGHFSKVFKRLMGTPCALKWREAG
                     ERERVWVVNPRHPIAEGLGENFVIENEEMYGEQFSVPEPLETVFISWFAGGEVFRSGL
                     TWRRGAGNIFYFRPGHETYPTYHDATVHKVLRNAVKWAYNPQGTYKAIHDAPNVPVEK
                     ALEPIVERGPRLHKAGEAGYR"
     misc_feature    complement(260871..261653)
                     /locus_tag="Smed_3808"
                     /note="Trehalose utilization protein [Carbohydrate
                     transport and metabolism]; Region: ThuA; COG4813"
                     /db_xref="CDD:227150"
     misc_feature    complement(261354..261356)
                     /locus_tag="Smed_3808"
                     /note="conserved cys residue [active]"
                     /db_xref="CDD:153222"
     gene            complement(261990..263018)
                     /locus_tag="Smed_3809"
                     /db_xref="GeneID:5318363"
     CDS             complement(261990..263018)
                     /locus_tag="Smed_3809"
                     /note="PFAM: ABC transporter related; TOBE domain protein;
                     Transport-associated OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20328 probable trehalosemaltose transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312554.1"
                     /db_xref="GI:150375958"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005116"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5318363"
                     /translation="MAELQLRDIRKSFGAFDVIKGVSMDIKSGEFMVFVGPSGCGKST
                     LLRLIAGLEEITSGTLSFDGQIVNQLTPSRRGIAMVFQSYALYPHMTVYENMAFGMQL
                     AGKDKQQCRKRVETAAEMLQLTPYLERLPRQLSGGQRQRVAIGRAIVRDPKVFLFDEP
                     LSNLDAALRVATRLEIAKLHRSMHKTTMIYVTHDQVEAMTLADRICVLRDGLVEQIGT
                     PLELYETPNSVFVAGFIGSPKMNFLSGAFAEPYKADTIGVRAEHLEIDGERGEWSGTV
                     IHSEMLGSDSYIYLDIGAGEPVIVRESGIAKHQPGERITISPAAGQVHRFDAGGRATG
                     RIEMRGAA"
     misc_feature    complement(262011..263018)
                     /locus_tag="Smed_3809"
                     /note="glycerol-3-phosphate transporter ATP-binding
                     subunit; Provisional; Region: ugpC; PRK11650"
                     /db_xref="CDD:236947"
     misc_feature    complement(262368..263009)
                     /locus_tag="Smed_3809"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    complement(262890..262913)
                     /locus_tag="Smed_3809"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(order(262440..262442,262542..262547,
                     262773..262775,262887..262895,262899..262904))
                     /locus_tag="Smed_3809"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(262773..262784)
                     /locus_tag="Smed_3809"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(262590..262619)
                     /locus_tag="Smed_3809"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(262542..262559)
                     /locus_tag="Smed_3809"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(262524..262535)
                     /locus_tag="Smed_3809"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(262434..262454)
                     /locus_tag="Smed_3809"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(262041..262253)
                     /locus_tag="Smed_3809"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            complement(263028..263858)
                     /locus_tag="Smed_3810"
                     /db_xref="GeneID:5318364"
     CDS             complement(263028..263858)
                     /locus_tag="Smed_3810"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20327 probable trehalosemaltose transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312555.1"
                     /db_xref="GI:150375959"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318364"
                     /translation="MVVTLVKRTAFYALVAVIILIAVFPFYYAILTSLKSGTALFRID
                     YWPTDFSLANYADIFSHGTFVRNLGNSLLVATLVVAISLLLAVTAAYALARVRFRGRG
                     LLLLTILSVSMFPQIAVLAGLFELIRFVGIFNTPLALIFSYMIFTLPFTVWVLTTFMR
                     DLPIEIEEAAIVDGASPWVVITRVFMPLMWPALVTTGLLAFIAAWNEFLFALTFTSSN
                     TQRTVPVAIALLSGGSQFEIPWGNIMAASVIVTVPLVVLVLIFQRRIISGLTAGGVKG
                     "
     misc_feature    complement(263034..263843)
                     /locus_tag="Smed_3810"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    complement(263121..>263528)
                     /locus_tag="Smed_3810"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(263124..263129,263133..263138,
                     263145..263150,263178..263183,263220..263225,
                     263232..263243,263262..263264,263271..263276,
                     263316..263318,263367..263369,263376..263381,
                     263391..263393,263397..263402,263409..263411,
                     263415..263417,263421..263426,263508..263510,
                     263514..263519,263526..263528))
                     /locus_tag="Smed_3810"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(263226..263243,263508..263528))
                     /locus_tag="Smed_3810"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(263148..263150,263178..263180,
                     263187..263189,263223..263225,263448..263450,
                     263508..263510))
                     /locus_tag="Smed_3810"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(263295..263297,263307..263312,
                     263328..263366))
                     /locus_tag="Smed_3810"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(263858..264844)
                     /locus_tag="Smed_3811"
                     /db_xref="GeneID:5318365"
     CDS             complement(263858..264844)
                     /locus_tag="Smed_3811"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20326 probable trehalosemaltose transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312556.1"
                     /db_xref="GI:150375960"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318365"
                     /translation="MTDLSLADRPAALAHGARIGSDLQAQRVRSAWLFLAPTFLVLAL
                     VAGWPLIRTIYFSFTNASLTNLSDAEFVGFANYFSWITLKSGRTIYRGLLADPAWWNA
                     VWNTLKFTVLSVSIETALGLIVALVLNAQFPGRGLVRAAILIPWAIPTIVSAKMWAWM
                     LNDQFGILNDMLLGLGLIGEKIAWTASPDTAMIAVLIVDVWKTTPFMALLILAGLQMV
                     PGDIYEAAKIDGVHPVRVFWRVTLPLIRPALMVAVIFRMLDALRIFDLIYVLTPNNAQ
                     TKTMSVMARENLFDFDKFAYGAAASTMLFLIIATITILYMWLGRLNLSGGER"
     misc_feature    complement(263885..264778)
                     /locus_tag="Smed_3811"
                     /note="ABC-type spermidine/putrescine transport system,
                     permease component II [Amino acid transport and
                     metabolism]; Region: PotC; COG1177"
                     /db_xref="CDD:224098"
     misc_feature    complement(263921..264535)
                     /locus_tag="Smed_3811"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(263921..263923,263930..263935,
                     263942..263947,263951..263956,263963..263968,
                     263996..264001,264038..264043,264050..264061,
                     264080..264082,264089..264094,264134..264136,
                     264185..264187,264194..264199,264209..264211,
                     264215..264220,264227..264229,264233..264235,
                     264242..264247,264320..264322,264326..264331,
                     264389..264418,264422..264433,264458..264460,
                     264473..264478,264485..264490))
                     /locus_tag="Smed_3811"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(264044..264061,264320..264331,
                     264383..264415))
                     /locus_tag="Smed_3811"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(263966..263968,263996..263998,
                     264005..264007,264041..264043,264260..264262,
                     264320..264322))
                     /locus_tag="Smed_3811"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(264113..264115,264125..264130,
                     264146..264184))
                     /locus_tag="Smed_3811"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(264933..266204)
                     /locus_tag="Smed_3812"
                     /db_xref="GeneID:5318366"
     CDS             complement(264933..266204)
                     /locus_tag="Smed_3812"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb20325 probable trehalosemaltose-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312557.1"
                     /db_xref="GI:150375961"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5318366"
                     /translation="MDVKPFIRTLISCAAIVGAIDVAAATELSMAANSTGKNLSFLRE
                     QIARFEKETGHKVNLVTMPASSSEQFSQYRLWLAAGNKDVDVYQTDVIWAPQLAEQFV
                     DLTEATKDVVADHFPSIIQSQTVNGKLVALPFYTDAPALYYRKDLLDKYGKAPPKTWD
                     EMAATAKEIQEKERAAGNADIWGFVFQGNAYEGLTCNALEWIKSSGGGQIVEPDGTIS
                     VNNEKAAAAVERVKEWIGTIAPKGVLAYQEEESRGVWQTGNAVFMRNWPYAYALGNGD
                     DSAVKGKFEVAPLPAAADGEKPSSTLGGWNLAVSKYSDEQEAAIAFVKFLGSAETQKV
                     RAIELSNLPTIAALYDDPEIAAAQPFMPHWKPIFESAVPRPSAVAKVKYNEVSSKFWS
                     AVHNTLSGNGTAAENLELLEVELTELKGDSW"
     sig_peptide     complement(266130..266204)
                     /locus_tag="Smed_3812"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.905) with cleavage site probability 0.579 at
                     residue 25"
     misc_feature    complement(265206..266108)
                     /locus_tag="Smed_3812"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     misc_feature    complement(265119..266075)
                     /locus_tag="Smed_3812"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_8; pfam13416"
                     /db_xref="CDD:222114"
     gene            266681..267703
                     /locus_tag="Smed_3813"
                     /db_xref="GeneID:5318367"
     CDS             266681..267703
                     /locus_tag="Smed_3813"
                     /EC_number="5.1.1.1"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: sme:SMb20324 putative ThuR, regulatory protein for
                     trehalosemaltose transport system"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="YP_001312558.1"
                     /db_xref="GI:150375962"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318367"
                     /translation="MKLKEFAKQLGLSPTTVSRALSGYPEVSEKTRKRVAEEAVRLGY
                     RPNINAVRLVTGRAGAIGVVMGRNEFQFCEFMSGMAERLDSEDIDILVSPVAVQDTKA
                     EIQLYSRLATSGRVDAVIVHSPKPNDERILLLHKLGIPFLVHGRSETNVPHAWLDIDN
                     EGAIRRATSHLLDLGHRRIALINGRDGLTFTLHRDKGYREALEQRGIPFDPRLVAHGQ
                     FTDEIGFRFARSLLEQSPRPTAFVAGSMMTALGVYRAVRSLDLVVGRDISVIAHDDVF
                     PYLTADNMAPSLSTSRSSLRAAGARLADLTLQLLAGRPASEIHELWPVELILRESTGP
                     AAEAAQ"
     misc_feature    266681..267682
                     /locus_tag="Smed_3813"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    266690..266845
                     /locus_tag="Smed_3813"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(266690..266692,266714..266728,266732..266737,
                     266744..266746,266759..266764,266771..266773,
                     266810..266812,266819..266821,266828..266833,
                     266837..266842)
                     /locus_tag="Smed_3813"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    266810..266839
                     /locus_tag="Smed_3813"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    266858..267661
                     /locus_tag="Smed_3813"
                     /note="Ligand-binding domain of DNA transcription
                     repressors specific for raffinose (RafR) and
                     alpha-glucosides (AglR) which are members of the LacI-GalR
                     family of bacterial transcription regulators; Region:
                     PBP1_AglR_RafR_like; cd06271"
                     /db_xref="CDD:107266"
     misc_feature    order(266891..266893,266903..266905,267107..267112,
                     267143..267154,267260..267262,267413..267415,
                     267497..267499)
                     /locus_tag="Smed_3813"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107266"
     gene            complement(267768..268457)
                     /locus_tag="Smed_3814"
                     /db_xref="GeneID:5318368"
     CDS             complement(267768..268457)
                     /locus_tag="Smed_3814"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20323 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312559.1"
                     /db_xref="GI:150375963"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318368"
                     /translation="MASHLKHRTLSGALIEEIRQAILSGRYPAGSQLRQDALAETYGV
                     SRIPVREVLFQLEAEGLVRIVPQKGAIVSELSLAEIDDVFELRALLEPRLLRKSAPLL
                     DGDDFARLDEAQNRFLKATTAGEIDSYGQLNAELHMVLYRRADMPRTQQIVASLLQTS
                     DRYTRVQLSSVAAMTRAMEEHAELIRLCRAGAFEEASAFLVFHLKAVHEDLLFRLNGR
                     EDAPAMEGGAG"
     misc_feature    complement(267795..268457)
                     /locus_tag="Smed_3814"
                     /note="Transcriptional regulators [Transcription]; Region:
                     GntR; COG1802"
                     /db_xref="CDD:224715"
     misc_feature    complement(268239..268433)
                     /locus_tag="Smed_3814"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(268248..268259,268263..268268,
                     268296..268298,268305..268310,268314..268328,
                     268350..268355,268356..268358,268425..268427,
                     268431..268433))
                     /locus_tag="Smed_3814"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(267840..268163)
                     /locus_tag="Smed_3814"
                     /note="FCD domain; Region: FCD; pfam07729"
                     /db_xref="CDD:219539"
     gene            268546..269151
                     /locus_tag="Smed_3815"
                     /db_xref="GeneID:5318369"
     CDS             268546..269151
                     /locus_tag="Smed_3815"
                     /note="PFAM: Tripartite ATP-independent periplasmic
                     transporter DctQ component;
                     KEGG: sme:SMb20322 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite ATP-independent periplasmic
                     transporter DctQ"
                     /protein_id="YP_001312560.1"
                     /db_xref="GI:150375964"
                     /db_xref="InterPro:IPR007387"
                     /db_xref="GeneID:5318369"
                     /translation="MNQSVEPPLYARAIIALSEALLSLEKLVVAGLMGVLLALILLNV
                     VTRYSGHPLYWVDESAVYAMVWLAFIGGSALTRLRLDFSVTLLTDYLPPAAARWMRAG
                     STLLVLLFALALAAFCWLWMDPVGIFRAGFDTKAFAAESFNFLYTERSQTLNWPIWAI
                     SLVIPLFAVTMTVHCAANLVEDLGLSPQQKRRELSSAEGVN"
     misc_feature    <268681..269109
                     /locus_tag="Smed_3815"
                     /note="TRAP-type C4-dicarboxylate transport system, small
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctM; COG3090"
                     /db_xref="CDD:225632"
     gene            269151..270416
                     /locus_tag="Smed_3816"
                     /db_xref="GeneID:5318370"
     CDS             269151..270416
                     /locus_tag="Smed_3816"
                     /note="TIGRFAM: TRAP dicarboxylate transporter, DctM
                     subunit;
                     PFAM: TRAP C4-dicarboxylate transport system permease DctM
                     subunit;
                     KEGG: sme:SMb20321 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctM"
                     /protein_id="YP_001312561.1"
                     /db_xref="GI:150375965"
                     /db_xref="InterPro:IPR004681"
                     /db_xref="InterPro:IPR010656"
                     /db_xref="GeneID:5318370"
                     /translation="MLTTAAFLAFMLVGVPIGVCLCLGSIVYILASGNPLLFQSFPTQ
                     LFGGVDNYGLISIPLFVLIGEIMNGGGITRRIIDMTMAFVGAMRGGLAYVNLLANMFV
                     ASILGSATAQVAVMAQMMVPEMEKKGYDKTFAAGITAYAGMLGPIIPPSIMFVVYSVL
                     AQVPVSDMLAAGIVPGVLLTVAFCLVIAAMGLVYNYPRGERMKLKDRVRIVLDALPTL
                     LIPFVIVGSVLSGLANATEAAAVGAVAAVLVGRFWIGELRFADLPRMMLRAGIYSAVV
                     LFLVAAAAVFSWVLVYGMVPQQVAGWVQTVASDPVTFMLLVNIILLIIGTVIDGAPGL
                     IMTVPILLPIATEVYGIDPIHFGVVVVVNLVLGFLSPPVGLCFFVAAAVTGAKPGKMF
                     LVTLPFFFVSCLMLVLLSLIPSLSTFFVR"
     sig_peptide     269151..269246
                     /locus_tag="Smed_3816"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.865) with cleavage site probability 0.783 at
                     residue 32"
     misc_feature    269163..270353
                     /locus_tag="Smed_3816"
                     /note="DctM-like transporters; Region: DctM; pfam06808"
                     /db_xref="CDD:219185"
     misc_feature    269283..270353
                     /locus_tag="Smed_3816"
                     /note="TRAP-type C4-dicarboxylate transport system, large
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctQ; COG1593"
                     /db_xref="CDD:224509"
     gene            270446..271441
                     /locus_tag="Smed_3817"
                     /db_xref="GeneID:5318371"
     CDS             270446..271441
                     /locus_tag="Smed_3817"
                     /note="PFAM: TRAP dicarboxylate transporter- DctP subunit;
                     KEGG: sme:SMb20320 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctP"
                     /protein_id="YP_001312562.1"
                     /db_xref="GI:150375966"
                     /db_xref="InterPro:IPR004682"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5318371"
                     /translation="MTVSRRTFLGGIAAGTALSLATPSLVRAQETRTLRLGIVTPPGH
                     PWNNAALKVGEGLKAETNGRLSLSVFPAGQLGNEAAMLQQMQSGALDLGWIMTAELGS
                     RIPAIAAINAPWVVDSTAKVAKLVREPLAMKLLDVLPAETGTVGLAWGITTMRVVFSA
                     REIAGLDDINGMKLRINTTPAYRDFYQLLGAAPTPIPTPAVFDAMSNGQVDGLEADLD
                     FSWNQRFDKVSKTMLKMNAIFMPCVALASGRAWQTLSAADREIITRLTKAALDEQIDA
                     TVANEPALLEKFAGAGIPIKDITVADASRIIAEYDKIWLPKAPVLAELRKVGATL"
     sig_peptide     270446..270532
                     /locus_tag="Smed_3817"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.992 at
                     residue 29"
     misc_feature    270458..271423
                     /locus_tag="Smed_3817"
                     /note="TRAP-type C4-dicarboxylate transport system,
                     periplasmic component [Carbohydrate transport and
                     metabolism]; Region: DctP; COG1638"
                     /db_xref="CDD:224553"
     misc_feature    270551..271387
                     /locus_tag="Smed_3817"
                     /note="Bacterial extracellular solute-binding protein,
                     family 7; Region: SBP_bac_7; cl15441"
                     /db_xref="CDD:210106"
     gene            271574..272788
                     /locus_tag="Smed_3818"
                     /db_xref="GeneID:5318010"
     CDS             271574..272788
                     /locus_tag="Smed_3818"
                     /note="PFAM: HI0933 family protein; FAD dependent
                     oxidoreductase; FAD-dependent pyridine
                     nucleotide-disulphide oxidoreductase;
                     KEGG: sme:SMb20319 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312563.1"
                     /db_xref="GI:150375967"
                     /db_xref="InterPro:IPR004792"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="GeneID:5318010"
                     /translation="MQSSEIAIIGGGPAGLMAAEILSRSGHAVTIYEAMPSAARKFLL
                     AGKSGLNITHSEHSKAFMQRFADASARLQPALDAFAPKDVRAWADELGAETFVGSSGR
                     VFPRAMKASPLLRAWLRRLEAQGVRLLTRHRWSGFAEDGYVFDTPEGRTLVRCDAALM
                     ALGGASWPRLGSDAAWVPPLRARGVPIRDLRPANCGFDVAWSGAFRERFAGQALKAVT
                     ATSGAGTIPGEFVMSRHGIEGSLVYAHAACLRDRLEQDGKASLMLDLAPGRTAERLAR
                     DLARQDRKASLSNRLRKGAGLDGVKAALLRELSQEATRIAPEQLAALIKALPVPVLAA
                     RPIAEAISSAGGVRLDGVDERYMVKAVPGLFVAGEMLDWEAPTGGYLLTACFATGRAA
                     ARGVKAWLDARP"
     misc_feature    271589..>271681
                     /locus_tag="Smed_3818"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:215691"
     misc_feature    271649..272776
                     /locus_tag="Smed_3818"
                     /note="uncharacterized flavoprotein, PP_4765 family;
                     Region: flavo_PP4765; TIGR03862"
                     /db_xref="CDD:163574"
     gene            complement(272805..273833)
                     /locus_tag="Smed_3819"
                     /db_xref="GeneID:5318011"
     CDS             complement(272805..273833)
                     /locus_tag="Smed_3819"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20318 putative sugar ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001312564.1"
                     /db_xref="GI:150375968"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318011"
                     /translation="MANAAATVAGMRDVPAAIRIMRWFIRHPPAVTFLLVVILCIVVG
                     TINPGFWQVSNLFDMARSTVVRGLFALGVLVVLASGGLDVSFTAIAALVMYVITMLVT
                     NYAPDLSIWPILGIAAASGAILGICNGLLVHALQAPSLIVTIGTQYAIRGFLLTFIGT
                     ALFMNIPESMDAFGKLALLRYEGANGAVATLPAYFLVLVVAASVTWYILNRTLIGRAL
                     YAVGGNAGIASRLGYNLRTVHVFVFAYAGLLAGIAGIMHVSSNRLANPFDLAGSELDV
                     IAAVILGGARITGGSGTVLGTLLGVLLITLVNNVLILVGIPSTLQLAIIGLFILAAGA
                     MFSIRPKS"
     misc_feature    complement(272976..273587)
                     /locus_tag="Smed_3819"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(272979..273587)
                     /locus_tag="Smed_3819"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(273102..273158)
                     /locus_tag="Smed_3819"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(273835..275421)
                     /locus_tag="Smed_3820"
                     /db_xref="GeneID:5318012"
     CDS             complement(273835..275421)
                     /locus_tag="Smed_3820"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20317 putative sugar ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312565.1"
                     /db_xref="GI:150375969"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318012"
                     /translation="MPMQSTIIAEQKMPSVEAQGGGTPFLEVRNLEKRFGGVRALKGV
                     SFTIERGRTYHLMGENGCGKSTLIKIISGAQPADGGELAINGKKTEGLTPIGALAAGI
                     ETVYQDLSLLPNLSVEENVALTQQLVASNGRLARRLDLKVLRETSIRALKEVGLPTEP
                     AFLSTPVEELPIATRQLIAIARAIASDAGLVIMDEPTTALTRREVDNLIRVVHGLHAK
                     GVSVLFVTHKLDECKAIGGQAIIMRDGLKVAECDVSTQSKSELGFWMTGKKLDETRYR
                     VDAHGDETLLSVEQLGGSGFDNVSFAVAKGEIFGITGLLDSGRNELALSLAGVEPARR
                     GSVLMGGKAADLSSPASAIAAGIGYVPEDRLSEGLFLGKSIRENIVMAVLDRLRGAFG
                     LLDSRRARALAQKTVDDLQVATPDIDNPVTSLSGGNQQRVLIGRWLTIEPSLLILHGP
                     TVGVDVGSKDTIFRIIQRLAGDGMSVIIISDDLPELLQNCDRVMVMRKGRVADVFTAE
                     GLEEDVIYKSMMAEAGQGVQ"
     misc_feature    complement(273856..275358)
                     /locus_tag="Smed_3820"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    complement(274672..275346)
                     /locus_tag="Smed_3820"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    complement(275227..275250)
                     /locus_tag="Smed_3820"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(274741..274743,274837..274842,
                     275101..275103,275224..275232,275236..275241))
                     /locus_tag="Smed_3820"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(275101..275112)
                     /locus_tag="Smed_3820"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(274885..274887,275038..275049,
                     275065..275079))
                     /locus_tag="Smed_3820"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(274837..274854)
                     /locus_tag="Smed_3820"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(274819..274830)
                     /locus_tag="Smed_3820"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(274735..274755)
                     /locus_tag="Smed_3820"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(273919..274575)
                     /locus_tag="Smed_3820"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            complement(275504..276505)
                     /locus_tag="Smed_3821"
                     /db_xref="GeneID:5318013"
     CDS             complement(275504..276505)
                     /locus_tag="Smed_3821"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     KEGG: sme:SMb20316 putative ABC transporter periplasmic
                     sugar-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001312566.1"
                     /db_xref="GI:150375970"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318013"
                     /translation="MSVYKKIATCTVALGALCAAQIAVAQDAPPVVTVVKVTGENWFT
                     RMEEGVVAYGKDNTGVSTSQIGPAKADAAQQLRLIEDLVAKNVSAIAVVPMDPSALEG
                     VFKRAMNRGIKIVTHEADSLKNTQVDIEAFDNKVFGARFNEKLAECMGKSGKWTSFVG
                     SLGSLTHVQWADGGAENAKKYPEMELVSEKNESFNDANKAYEKAREILRKYPDIKGFQ
                     GGSAIDVIGIGRAVEEAGLVGKVCVVGLGLPKDTAKYLESGAVQSISFWDPKDAGYVM
                     NKVAQLVIEGKEITDGMDLGVPGYNKVSVKQGPGEGIIVVGEAWVDVDKSNYSQYPF"
     misc_feature    complement(275585..276505)
                     /locus_tag="Smed_3821"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     RbsB; COG1879"
                     /db_xref="CDD:224791"
     sig_peptide     complement(276428..276505)
                     /locus_tag="Smed_3821"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 26"
     misc_feature    complement(275519..276415)
                     /locus_tag="Smed_3821"
                     /note="Periplasmic binding domain of autoinducer-2 (AI-2)
                     receptor LsrB from Salmonella typhimurium and its close
                     homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302"
                     /db_xref="CDD:107297"
     misc_feature    complement(order(275705..275707,275840..275848,
                     275996..275998,276005..276010,276113..276115,
                     276152..276154,276398..276400))
                     /locus_tag="Smed_3821"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107297"
     gene            complement(276586..277572)
                     /locus_tag="Smed_3822"
                     /db_xref="GeneID:5318014"
     CDS             complement(276586..277572)
                     /locus_tag="Smed_3822"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20315 putative sugar ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001312567.1"
                     /db_xref="GI:150375971"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318014"
                     /translation="MKSVFADRQFNFLVATNVLVVALAVVFAGDTFLSLYNFQSMSAQ
                     VPELALLALGVMLAMIAGNGGIDLSGIALANLAGVGSYLLMRDWVSVDEVPLAFSWLF
                     ALIALLIGLAGGMLNGALIAFAGLTPIIATLGTQLFFTGLAVAFTNGSAITLGYIEPL
                     DNFGNTPVLGLPMCFTLFVAIAVLIGVVLRYTPFGFKLYLMGSNAKAARYAGIPQRRI
                     LLLTYTVCGVLASVAGIIIAARTSSVKWDYGSSYVLIAILIVVMAGVRPDGGYGRTVC
                     VVLSATALQMLSSLFNFLDISNFFRDCAWGLLLIVFLATSRVDLRAFISPRR"
     sig_peptide     complement(277486..277572)
                     /locus_tag="Smed_3822"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.825) with cleavage site probability 0.807 at
                     residue 29"
     misc_feature    complement(276631..277383)
                     /locus_tag="Smed_3822"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(276634..>277191)
                     /locus_tag="Smed_3822"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(276901..276957)
                     /locus_tag="Smed_3822"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            277942..278934
                     /locus_tag="Smed_3823"
                     /db_xref="GeneID:5318015"
     CDS             277942..278934
                     /locus_tag="Smed_3823"
                     /EC_number="2.7.1.29"
                     /note="PFAM: Dak kinase;
                     KEGG: sme:SMb20314 putative dihydroxyacetone kinase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerone kinase"
                     /protein_id="YP_001312568.1"
                     /db_xref="GI:150375972"
                     /db_xref="InterPro:IPR004006"
                     /db_xref="GeneID:5318015"
                     /translation="MQRFINNPDEVVEDTVKGFVKAHADIVRLGENPRVIVAKNAPVA
                     GKVGVVTGGGSGHEPAFIGYTGRNMLDAVAVGELFSSPTAKSFHDAMREANGGEGVVC
                     LYGNYAGDNMNVKMAVKLAAKEGIEIATVVANDDVCSAPPEEREKRRGVAGEIFMWKI
                     GGAKAAAGAPLEEVRATAQKAIDNCRSIGVGLGPCTLPAVGHPNFRIEPGTMEVGIGH
                     HGEPGLRVEALKTADEVAKDMCKIVLDDHGLPDGTEVAVLVSGLGATPLNELYILNDT
                     IEREIRARGLKIYRTYVGNYFTSLEMVGATLTVMALDDELKALLDVEVRCTAVF"
     misc_feature    277942..278931
                     /locus_tag="Smed_3823"
                     /note="dihydroxyacetone kinase subunit DhaK; Provisional;
                     Region: PRK14481; cl10557"
                     /db_xref="CDD:245332"
     misc_feature    277942..278922
                     /locus_tag="Smed_3823"
                     /note="Dihydroxyacetone kinase [Carbohydrate transport and
                     metabolism]; Region: DAK1; COG2376"
                     /db_xref="CDD:225251"
     gene            278944..279585
                     /locus_tag="Smed_3824"
                     /db_xref="GeneID:5318016"
     CDS             278944..279585
                     /locus_tag="Smed_3824"
                     /note="TIGRFAM: dihydroxyacetone kinase, L subunit;
                     PFAM: Dak phosphatase;
                     KEGG: sme:SMb20313 putative dihydroxyacetone kinase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="YP_001312569.1"
                     /db_xref="GI:150375973"
                     /db_xref="InterPro:IPR004007"
                     /db_xref="InterPro:IPR012737"
                     /db_xref="GeneID:5318016"
                     /translation="MQTFENAKAGDIVQALAERIIENRAYLSEIDGKIGDGDHGVNMA
                     KGFGLAAERLKDKDASLAEALETLGTVLMTEIGGSMGPLYGVMFTEFAEKIEAVDAID
                     ATAYSRMLHAGLEGIQSIGSAKVGDKTLLDSFVPAVEAFDAAIAAGRSFAEALEALTA
                     AAEAGRDSTRDLVAKIGRASRLGERSLGVLDAGATSCAIILRELSGGARARLR"
     misc_feature    279040..279558
                     /locus_tag="Smed_3824"
                     /note="DAK2 domain; Region: Dak2; pfam02734"
                     /db_xref="CDD:217208"
     gene            279700..281787
                     /locus_tag="Smed_3825"
                     /db_xref="GeneID:5318017"
     CDS             279700..281787
                     /locus_tag="Smed_3825"
                     /EC_number="2.7.1.29"
                     /note="PFAM: Dak kinase; putative sugar-binding domain
                     protein;
                     KEGG: sme:SMb20312 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerone kinase"
                     /protein_id="YP_001312570.1"
                     /db_xref="GI:150375974"
                     /db_xref="InterPro:IPR004006"
                     /db_xref="InterPro:IPR007324"
                     /db_xref="GeneID:5318017"
                     /translation="MTMKTPSPRKGGANRGGTMDGSDAIPLRYGDDPYVWACWLYYED
                     GMTQSEIAEAMGVSRATVNSYLADAREKGIVNISIEPARLASLTVAQELKRHFGLTDC
                     LVVPSDDNARPLIDRLGAAGAQALPKLLKSGDTLAVAWGRTVLSVGEHAGITSLQDMT
                     VVQATGGTTASFPYTPELCASAVARAIAARCVNITAPAVVRSPELLQMLLDEPLVREQ
                     FATLARSNRVLFGISSLRPNSTIHTSGFFESVSLQDYLAAGAVGVVAGRFIDERGRPV
                     AGPLDHRTVGISLDLLRRIGTRIAVAGGFDKVPALLAALRGGYVNVLITDAATGHGIL
                     RADGGTALDSRLSHRPKLVQTLSTYRSHVKKFLNNPNEVVEEMLDGVVKAHEKYLKPI
                     NGSHRALAARSGPRPEKVGLVIGGGTGHEPCFLGYVGKGLADAVAVGNIFSSPPPDPI
                     VQCAEAASGGAGVLFVYGNYAGDVMNFEMAAEIAEEKGIRVQTVLTTDDIASSPIEDR
                     EGRRGVAGNFFIFKIAGAACDRGLSLEACAAVTRKANLRTYTMGVALEPGAMPQTRRH
                     NFEIGPEDMEVGMGIHGEPGVTRERIRSADEITDSVMDRVFNEMKAAPGDRVAVLVNS
                     FGATPLMELYILFRRVQQRLAAKDILIEANWIGHYCTSLDMVGASITILHLDQELSEL
                     LHHPCETAFLKIN"
     misc_feature    279766..280713
                     /locus_tag="Smed_3825"
                     /note="Transcriptional regulator, contains sigma
                     factor-related N-terminal domain [Transcription]; Region:
                     DeoR; COG2390"
                     /db_xref="CDD:225263"
     misc_feature    <279817..279915
                     /locus_tag="Smed_3825"
                     /note="Sigma70, region (SR) 4 refers to the most
                     C-terminal of four conserved domains found in Escherichia
                     coli (Ec) sigma70, the main housekeeping sigma, and
                     related sigma-factors (SFs). A SF is a dissociable subunit
                     of RNA polymerase, it directs bacterial or...; Region:
                     Sigma70_r4; cd06171"
                     /db_xref="CDD:100119"
     misc_feature    order(279820..279822,279838..279843,279871..279873,
                     279877..279882,279886..279894,279898..279903,
                     279907..279909)
                     /locus_tag="Smed_3825"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:100119"
     misc_feature    279967..280704
                     /locus_tag="Smed_3825"
                     /note="Putative sugar-binding domain; Region: Sugar-bind;
                     pfam04198"
                     /db_xref="CDD:217959"
     misc_feature    280786..281772
                     /locus_tag="Smed_3825"
                     /note="Dihydroxyacetone kinase [Carbohydrate transport and
                     metabolism]; Region: DAK1; COG2376"
                     /db_xref="CDD:225251"
     misc_feature    280789..281778
                     /locus_tag="Smed_3825"
                     /note="dihydroxyacetone kinase subunit DhaK; Provisional;
                     Region: PRK14481"
                     /db_xref="CDD:237724"
     gene            281893..282531
                     /locus_tag="Smed_3826"
                     /db_xref="GeneID:5318018"
     CDS             281893..282531
                     /locus_tag="Smed_3826"
                     /note="TIGRFAM: dihydroxyacetone kinase, L subunit;
                     PFAM: Dak phosphatase;
                     KEGG: sme:SMb20307 putative dihydroxyacetone kinase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="YP_001312571.1"
                     /db_xref="GI:150375975"
                     /db_xref="InterPro:IPR004007"
                     /db_xref="InterPro:IPR012737"
                     /db_xref="GeneID:5318018"
                     /translation="MSEIAVRRLIEMFDAISSDIGAERDRLSELDGAIGDADHGITMA
                     IGFSAVTSELARTDASSAELSSVMTAAASAFLNAVGASTGPLYATAFRRAAQALEGCD
                     ALDLGTCALLVQSIASGIRERGKGQRGDKTMLDVWLPAADAAAQAIAAGKPADAFWAD
                     VTAAAQNGANATRSMVATKGRAARLGERSLGHMDPGAASAVLIIGAMARTLR"
     misc_feature    281920..282516
                     /locus_tag="Smed_3826"
                     /note="DAK2 domain; Region: Dak2; cl03685"
                     /db_xref="CDD:243501"
     gene            282781..284127
                     /locus_tag="Smed_3827"
                     /db_xref="GeneID:5318535"
     CDS             282781..284127
                     /locus_tag="Smed_3827"
                     /note="PFAM: transposase IS4 family protein;
                     KEGG: nha:Nham_2758 transposase, IS4"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS4 family protein"
                     /protein_id="YP_001312572.1"
                     /db_xref="GI:150375976"
                     /db_xref="InterPro:IPR002559"
                     /db_xref="GeneID:5318535"
                     /translation="MSRPRERRETGEQDLFRSRLDQIINMRHELVRLAQAIDWPLLEG
                     RFGEVYCDGPGMPPLPTRLMAGLAILKHTFDLSDEELCARWVENPYFQYLCGEEFFRH
                     DLPFDRSSMTRWRARMGEERLTALLQESLAVAVKTGAMQPQDTRRVIVDTTVQPKNVM
                     FPTDAKLLHRARERLVRLAKKAGLTLRQSYIRVGKLALIKHQRYAHAKQFKRANKALR
                     TLRTYLGRTIRDIRRQIGDDEKLRSIFLWPLHQASTVLEQRQRQRGRKIYSLHAPEVE
                     CIGKGKAHRPYEFGVKVSVATTLKRSKGGQFALHAKAMPGNPYDGHTLATVIPEMEKT
                     VGNEIARILADAGYRGHNAPASHRFRIFTSGQKRRVTLAIKREMRRRSAIEPVIGHLK
                     AEHRMGRNYLAGQHGDAINAVLAAAGYNFSLLLNWLRQFFWLLFAWVHAAANPNAA"
     misc_feature    282943..283173
                     /locus_tag="Smed_3827"
                     /note="Transposase domain (DUF772); Region: DUF772;
                     pfam05598"
                     /db_xref="CDD:203284"
     gene            complement(284177..284404)
                     /locus_tag="Smed_3828"
                     /db_xref="GeneID:5318536"
     CDS             complement(284177..284404)
                     /locus_tag="Smed_3828"
                     /note="KEGG: sme:SMb20303 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312573.1"
                     /db_xref="GI:150375977"
                     /db_xref="GeneID:5318536"
                     /translation="MWLRFSDIAMGDDEISMLRRVHAYACSFRELEPDSEHGAEVGKM
                     LFHLYQKGVRSELALMQMLTAGDGPAAPEAG"
     gene            complement(284665..285255)
                     /locus_tag="Smed_3829"
                     /db_xref="GeneID:5318537"
     CDS             complement(284665..285255)
                     /locus_tag="Smed_3829"
                     /note="KEGG: rle:RL0552 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312574.1"
                     /db_xref="GI:150375978"
                     /db_xref="GeneID:5318537"
                     /translation="MRGASALIFGGLLLTAPVCAAQTIPWKDVSGWSVLIDPSTGNGC
                     FISTMYEDGTILRLGFNFFQSQTKIYLALGNSDWKSLEVGKDYPVQIQFDRNPVWNAT
                     AQGIDFGGINFLSVSTTDTNFAEEFSRKLGMRATFNGREVAALGLKGSARAVTEMINC
                     QESVNAAASARSTPQSPKDPFEAAPDKKSANDPFEL"
     sig_peptide     complement(285193..285255)
                     /locus_tag="Smed_3829"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.685 at
                     residue 21"
     gene            285419..285580
                     /locus_tag="Smed_3830"
                     /db_xref="GeneID:5318538"
     CDS             285419..285580
                     /locus_tag="Smed_3830"
                     /note="KEGG: sme:SMb20302 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312575.1"
                     /db_xref="GI:150375979"
                     /db_xref="GeneID:5318538"
                     /translation="MSVLISILITFLVVILVLYLVNRLSLDARTKQIVQAIVIIIGIL
                     SLLRYLAVF"
     gene            complement(285619..287550)
                     /locus_tag="Smed_3831"
                     /db_xref="GeneID:5318539"
     CDS             complement(285619..287550)
                     /locus_tag="Smed_3831"
                     /note="PFAM: adenylyl cyclase class-3/4/guanylyl cyclase;
                     Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat
                     protein;
                     KEGG: sme:SMb20300 putative adenylate cyclase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl cyclase class-3/4/guanylyl cyclase"
                     /protein_id="YP_001312576.1"
                     /db_xref="GI:150375980"
                     /db_xref="InterPro:IPR001054"
                     /db_xref="InterPro:IPR011717"
                     /db_xref="InterPro:IPR013026"
                     /db_xref="InterPro:IPR013105"
                     /db_xref="GeneID:5318539"
                     /translation="MERKLAAIVAGDIVGYTRLMSEDESSTYSALREVFSALITPAVE
                     KHGGRTFKTTGDGFLATFPSVNEALDAAIEIQNGFADRPFDMRLGINLGDVIEVDGDM
                     FGDGVNVASRLEAMAEPGGIFVSEAVVRSADRNRSKLFYSIGRRQAKNIPEPLAVYAV
                     RLGADEESPSGWFGRTARGRRAALPYAIGAAAFVLIAAATQAPAVRAIGADMVDSFGR
                     LTGAELADARPTVAVLPFDDMSGGADQAYFADGLTEDIIANLARNRELQVIARNSTFA
                     LRGQAEDIRRIGERLGAGYVVEGSARRAGDQLRVVAQLIDARSGAHLWSRSYDRRVED
                     IFSVQTELTAEIVSHLVSYVRESEVSNAAEQPTENLQAYDLVLQARNRYKHGSKDAEA
                     LIASRALLHRALELDPGYAAARASLGMTYIVDFVQNLTGRATVTDVETGLSESRQAVR
                     LDPNLAVGYQVLSFGLSATGDYPGAMQAAQRAVELNPNDPDSLMALAKAQVRFGSYDE
                     AVQNAERARRLHPMAPEYYTYVYGQALYAAGRLDEADEVLRECLIRAPREPDCLLIQT
                     AVLSQRGDAQGAQRTMARLTEADPEFSLASERALRRFGDTALMEQFLSQLSEANAPDV
                     TSGFVQPPPQARIQTANSL"
     misc_feature    complement(287059..287541)
                     /locus_tag="Smed_3831"
                     /note="Adenylate cyclase, family 3 (some proteins contain
                     HAMP domain) [Signal transduction mechanisms]; Region:
                     CyaA; COG2114"
                     /db_xref="CDD:225025"
     misc_feature    complement(287071..287535)
                     /locus_tag="Smed_3831"
                     /note="cyclase homology domain; Region: CHD; cd07302"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(287104..287106,287215..287220,
                     287227..287232,287242..287250,287374..287376,
                     287383..287391,287395..287397,287500..287517,
                     287521..287523))
                     /locus_tag="Smed_3831"
                     /note="nucleotidyl binding site; other site"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(287383..287385,287515..287517))
                     /locus_tag="Smed_3831"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(287104..287106,287227..287229,
                     287236..287247,287263..287265,287392..287397,
                     287431..287433,287446..287448,287455..287460,
                     287467..287469,287500..287502))
                     /locus_tag="Smed_3831"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143636"
     misc_feature    complement(286483..286938)
                     /locus_tag="Smed_3831"
                     /note="Predicted integral membrane protein [Function
                     unknown]; Region: COG5616"
                     /db_xref="CDD:227903"
     misc_feature    complement(286087..286434)
                     /locus_tag="Smed_3831"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cd00189"
                     /db_xref="CDD:238112"
     misc_feature    complement(order(286144..286149,286156..286161,
                     286168..286173,286249..286254,286294..286299,
                     286303..286308,286408..286413,286420..286425,
                     286429..286434))
                     /locus_tag="Smed_3831"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     misc_feature    complement(order(286105..286107,286114..286116,
                     286126..286128,286162..286164,286207..286209,
                     286216..286218,286228..286230,286297..286299,
                     286342..286344,286351..286353,286375..286377,
                     286414..286416))
                     /locus_tag="Smed_3831"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     misc_feature    complement(285988..286191)
                     /locus_tag="Smed_3831"
                     /note="TPR repeat; Region: TPR_11; pfam13414"
                     /db_xref="CDD:222112"
     misc_feature    complement(285883..286155)
                     /locus_tag="Smed_3831"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cd00189"
                     /db_xref="CDD:238112"
     misc_feature    complement(order(285898..285900,285907..285909,
                     285919..285921,285955..285957,286003..286005,
                     286012..286014,286024..286026,286060..286062,
                     286105..286107,286114..286116,286126..286128))
                     /locus_tag="Smed_3831"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     misc_feature    complement(285874..286071)
                     /locus_tag="Smed_3831"
                     /note="Tetratricopeptide repeat; Region: TPR_16;
                     pfam13432"
                     /db_xref="CDD:222123"
     misc_feature    complement(order(285937..285942,285949..285954,
                     285961..285966,286045..286050,286057..286062,
                     286066..286071))
                     /locus_tag="Smed_3831"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     gene            complement(287784..288692)
                     /locus_tag="Smed_3832"
                     /db_xref="GeneID:5318540"
     CDS             complement(287784..288692)
                     /locus_tag="Smed_3832"
                     /EC_number="4.1.3.3"
                     /note="catalyzes the formation of pyruvate and
                     N-acetylmannosamine from N-acetylneuraminic acid"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="YP_001312577.1"
                     /db_xref="GI:150375981"
                     /db_xref="InterPro:IPR002220"
                     /db_xref="GeneID:5318540"
                     /translation="MQLEGIFSALLTPFSEDEAIDRQAVGALVDFQVGLGIDGVYVGG
                     SSGEAMLQSLDERADYLSDVAAAGAGRLKLIAHIGTIATKDALSLSQHAAKSGYQAIS
                     AIPPFYYDFSRPEVMAHYRELADASALPLIVYNFPARTSGFTLPELVELLSHPNIIGI
                     KHTSSDMFQLERLRNAAPDAIVYNGYDEMCLAGFAMGAQGAIGTTYNFMGDVFVSLRA
                     CAAAGRIVEARQLQAMANRVIQVLIKVGVMPGSKALLGIMGIASGRSRRPFRKVEEAD
                     LAALREALAPVLAWRESGRAASGLTG"
     misc_feature    complement(287823..288692)
                     /locus_tag="Smed_3832"
                     /note="N-acetylneuraminate lyase; Provisional; Region:
                     PRK04147"
                     /db_xref="CDD:179749"
     misc_feature    complement(287877..288686)
                     /locus_tag="Smed_3832"
                     /note="N-Acetylneuraminic acid aldolase, also called
                     N-acetylneuraminate lyase (NAL); Region: NAL; cd00954"
                     /db_xref="CDD:188641"
     misc_feature    complement(order(288210..288212,288291..288293,
                     288555..288563,288570..288572,288666..288668))
                     /locus_tag="Smed_3832"
                     /note="inhibitor site; inhibition site"
                     /db_xref="CDD:188641"
     misc_feature    complement(order(288087..288089,288210..288212,
                     288291..288293,288555..288563,288570..288572))
                     /locus_tag="Smed_3832"
                     /note="active site"
                     /db_xref="CDD:188641"
     misc_feature    complement(order(287889..287894,288336..288338,
                     288348..288350,288369..288374,288444..288449,
                     288540..288545,288558..288560))
                     /locus_tag="Smed_3832"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188641"
     misc_feature    complement(288210..288212)
                     /locus_tag="Smed_3832"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188641"
     gene            complement(288706..289641)
                     /locus_tag="Smed_3833"
                     /db_xref="GeneID:5318541"
     CDS             complement(288706..289641)
                     /locus_tag="Smed_3833"
                     /note="PFAM: dihydrodipicolinate synthetase;
                     KEGG: sme:SMb20298 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthetase"
                     /protein_id="YP_001312578.1"
                     /db_xref="GI:150375982"
                     /db_xref="InterPro:IPR002220"
                     /db_xref="GeneID:5318541"
                     /translation="MSICAKRPEGIWGAVLLPIDRRGEIEWSALHEQLSTLHESGLEG
                     IYTNGTAGEFHSQTEQEFDRLSQLVAEFCRLVALPFQIGVSHSNARVARERLARIASL
                     RPDAAQVTLPDWWAPSYEEAEAFLAGMAATAPEVPLVLYNPPHAKRRLSHGEIAKLRT
                     AIPTLIGAKLPGGDEFWYEELRRKLPDFSVFIPGHFMASGCLAGGRGSYSNVACLSPA
                     GALGWWRQLREDPAGALAFESRVIAFMNEQVLPLAVRYGLSNAALDKALAAAGRWCSM
                     GPHLLWPYSCAPEEAVAELGGAARRQLPELFSMNQ"
     misc_feature    complement(288724..289629)
                     /locus_tag="Smed_3833"
                     /note="Dihydrodipicolinate synthase/N-acetylneuraminate
                     lyase [Amino acid transport and metabolism / Cell envelope
                     biogenesis, outer membrane]; Region: DapA; COG0329"
                     /db_xref="CDD:223406"
     misc_feature    complement(288757..289611)
                     /locus_tag="Smed_3833"
                     /note="Dihydrodipicolinate synthase family; Region:
                     DHDPS-like; cd00408"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(289135..289137,289219..289221,
                     289489..289497,289504..289506,289600..289602))
                     /locus_tag="Smed_3833"
                     /note="inhibitor site; inhibition site"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(289015..289017,289135..289137,
                     289219..289221,289489..289497,289504..289506))
                     /locus_tag="Smed_3833"
                     /note="active site"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(288793..288798,289267..289269,
                     289279..289281,289300..289305,289375..289380,
                     289474..289479,289492..289494))
                     /locus_tag="Smed_3833"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188630"
     misc_feature    complement(289135..289137)
                     /locus_tag="Smed_3833"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188630"
     gene            complement(289638..290918)
                     /locus_tag="Smed_3834"
                     /db_xref="GeneID:5318542"
     CDS             complement(289638..290918)
                     /locus_tag="Smed_3834"
                     /note="TIGRFAM: TRAP dicarboxylate transporter, DctM
                     subunit;
                     PFAM: TRAP C4-dicarboxylate transport system permease DctM
                     subunit;
                     KEGG: sme:SMb20297 putative permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctM"
                     /protein_id="YP_001312579.1"
                     /db_xref="GI:150375983"
                     /db_xref="InterPro:IPR004681"
                     /db_xref="InterPro:IPR010656"
                     /db_xref="GeneID:5318542"
                     /translation="MTTLFGGWFALLVAGMPVGFTLIVAALAYMLWQGTGLNFAGQRM
                     IAGLNSFPLLAVPFFILTAQLMNLSGVTERIFAFAKALVGHVRGGLGHVNIMASVMFS
                     GMSGSAVADAAGLGQLEIKAMRDAGYDEQFSGSVTAASAIIGPLIPPSIPLVVYGVIA
                     NTSIGGLFLGGIVPGLLCAISLMVMVYVIAWRRNYPTEERSSLRRIWSTFWRALLPLI
                     TPFIIIGGIFAGIFSPTEAAVVAASYALFLGVVVYREITFAKLVIVLRETVSHTAAVG
                     LLIMGVSLFGYVIAREQVPQHVAAFFLAYADDPLTFLILVNLMLLALGTFIEALAILL
                     LIVPVLVPTALQFGVDPVHFGVMVVFNLMIGILTPPMGVALFVVSKVADIPFGLLARG
                     ILPLLVPLVLVLVLITLFPALVTFIPDQMLGAAR"
     sig_peptide     complement(290832..290918)
                     /locus_tag="Smed_3834"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.969) with cleavage site probability 0.799 at
                     residue 29"
     misc_feature    complement(289680..290906)
                     /locus_tag="Smed_3834"
                     /note="DctM-like transporters; Region: DctM; pfam06808"
                     /db_xref="CDD:219185"
     misc_feature    complement(289656..290789)
                     /locus_tag="Smed_3834"
                     /note="TRAP-type C4-dicarboxylate transport system, large
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctQ; COG1593"
                     /db_xref="CDD:224509"
     gene            complement(290918..291436)
                     /locus_tag="Smed_3835"
                     /db_xref="GeneID:5318543"
     CDS             complement(290918..291436)
                     /locus_tag="Smed_3835"
                     /note="PFAM: Tripartite ATP-independent periplasmic
                     transporter DctQ component;
                     KEGG: sme:SMb20296 putative permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite ATP-independent periplasmic
                     transporter DctQ"
                     /protein_id="YP_001312580.1"
                     /db_xref="GI:150375984"
                     /db_xref="InterPro:IPR007387"
                     /db_xref="GeneID:5318543"
                     /translation="MAASSRRRSLAHIEETLAAILLVFAFVVIALQIVTRFVFRDPMF
                     WTEEAARYAFVWLVALGAAEGVTSRTHITMDIVPRMLPERVQLLLRLVLDLVVLAALL
                     VLVYYGIFGAMRAHKVMSIAIGVPESWLYGALPVFGLLAAIRILLVMARDVRLLFDSG
                     RPAVDAPSERYL"
     misc_feature    complement(290921..291436)
                     /locus_tag="Smed_3835"
                     /note="TRAP-type C4-dicarboxylate transport system, small
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctM; COG3090"
                     /db_xref="CDD:225632"
     gene            complement(291530..292501)
                     /locus_tag="Smed_3836"
                     /db_xref="GeneID:5318544"
     CDS             complement(291530..292501)
                     /locus_tag="Smed_3836"
                     /note="TIGRFAM: TRAP dicarboxylate transporter, DctP
                     subunit;
                     PFAM: TRAP dicarboxylate transporter- DctP subunit;
                     KEGG: sme:SMb20295 putative ABC transporter periplasmic
                     substrate-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctP"
                     /protein_id="YP_001312581.1"
                     /db_xref="GI:150375985"
                     /db_xref="InterPro:IPR004682"
                     /db_xref="GeneID:5318544"
                     /translation="MKKGLISLALAGLLMASQAMAQEARTLRLGMQGTAGDPQFEGVT
                     EAARIIKEKSGGRLTLEIFPNSQLGTFTEMMEQVTLGELDFTLNPFGGMDAWVPRAVL
                     ASTAYVVGDFEHLQKIIASDWGKGIVDELRTEHKWRMVDSWYFGTRHTTAKKPIEKPA
                     DFNGMKLRVPNSAPLLTWAKAMGASPTPVAFAEVYLALQTNQVDGQENPLPIIDSMKF
                     TEVQTHVSLTGHLVQDQVVLMSEDTWNALDPSDQKLVMEAFEAGGALNDKLVANKETS
                     LVSDFRERGITVVEPDKAAFQEAMKPVYADLDARFGAGTVQTLLDLR"
     misc_feature    complement(291533..292501)
                     /locus_tag="Smed_3836"
                     /note="TRAP-type C4-dicarboxylate transport system,
                     periplasmic component [Carbohydrate transport and
                     metabolism]; Region: DctP; COG1638"
                     /db_xref="CDD:224553"
     sig_peptide     complement(292436..292501)
                     /locus_tag="Smed_3836"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 22"
     misc_feature    complement(291584..292417)
                     /locus_tag="Smed_3836"
                     /note="Bacterial extracellular solute-binding protein,
                     family 7; Region: SBP_bac_7; pfam03480"
                     /db_xref="CDD:202660"
     gene            complement(292628..293329)
                     /locus_tag="Smed_3837"
                     /db_xref="GeneID:5318565"
     CDS             complement(292628..293329)
                     /locus_tag="Smed_3837"
                     /note="Transcriptional repressor of the nan operon that
                     encodes proteins involved in sialic acid utilization"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="YP_001312582.1"
                     /db_xref="GI:150375986"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318565"
                     /translation="MSTLAVRKKLSDEVRLKLEEMIRDEIYPLDSTLPSERDLMELFG
                     VGRPSIREALYALERMGLVKISTGERAKVTRPTPDHFLTSLAGAARMLLGRPEGVANF
                     EQARLFLEEGCARHLAAYATAEQIAAIDAALARNEAAIGKARAFAATDVAFHRTLTQM
                     VSNPIFVAVHDAFVDWLIGQRPLPTKPEISNRESFDEHVAIVEAIRARDPEHAGRVMR
                     EHLESAARKYRQTNP"
     misc_feature    complement(292631..293329)
                     /locus_tag="Smed_3837"
                     /note="transcriptional regulator NanR; Provisional;
                     Region: PRK03837"
                     /db_xref="CDD:235166"
     misc_feature    complement(293108..293305)
                     /locus_tag="Smed_3837"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(293117..293128,293132..293137,
                     293165..293167,293174..293179,293183..293197,
                     293219..293224,293228..293230,293297..293299,
                     293303..293305))
                     /locus_tag="Smed_3837"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(292661..>292909)
                     /locus_tag="Smed_3837"
                     /note="FCD domain; Region: FCD; pfam07729"
                     /db_xref="CDD:219539"
     gene            complement(293484..294047)
                     /locus_tag="Smed_3838"
                     /db_xref="GeneID:5318566"
     CDS             complement(293484..294047)
                     /locus_tag="Smed_3838"
                     /note="KEGG: sme:SMb20293 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312583.1"
                     /db_xref="GI:150375987"
                     /db_xref="GeneID:5318566"
                     /translation="MLRSLRFIKQGGYLRKSACCRMSADRWHSLDSRGEFPWQSPIIG
                     PPECGVGGTKAMSGCFLPSNGSTAMATIRYEIVEHDGGWAYKVDDVFSEAFATHADAL
                     AAAEIAARHHELPGSTEEIEFQDTDGRWHEQVASGFDRPHTKVVDTPEERNVGERPSA
                     AEPRSSLQTFLLLAGLGLAIGYFVRRH"
     gene            294180..295163
                     /locus_tag="Smed_3839"
                     /db_xref="GeneID:5318567"
     CDS             294180..295163
                     /locus_tag="Smed_3839"
                     /note="TIGRFAM: TRAP transporter solute receptor, TAXI
                     family;
                     KEGG: sme:SMb20292 hypothetical immunogenic protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter solute receptor TAXI family
                     protein"
                     /protein_id="YP_001312584.1"
                     /db_xref="GI:150375988"
                     /db_xref="InterPro:IPR011852"
                     /db_xref="GeneID:5318567"
                     /translation="MRHERITLRGAQIAALSAAMFFSGSAVAQQKFVTIGTGGVTGVY
                     YAAGGAICRLLNKDRKTHGIRCSVESTGGSAFNVNTIKEGELDFGTTQSDVQYNAMKG
                     EESFKEGGAHTDLRAVFSIHPEPFTVLAHPNAGVTRFEDFKGKRFNVGNPGSGTRASM
                     ERLLGAMGWTLADFSLASELKADEHGPALCDGKIDGFFYGVGHPSANIQDPTTTCGAK
                     LVPLTGEVVDKLVAENPYYAKATIPGGLYNGNPEDTETFGVLATLVTSANVPEESVYE
                     LTKAVFENFDEFKSLHPAFANLDPAKMIKDGLSAPLHPGAERYYKEKGWLK"
     misc_feature    294180..295151
                     /locus_tag="Smed_3839"
                     /note="TRAP transporter solute receptor, TAXI family;
                     Region: TRAP_TAXI; TIGR02122"
                     /db_xref="CDD:233736"
     sig_peptide     294180..294266
                     /locus_tag="Smed_3839"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.998 at
                     residue 29"
     misc_feature    294204..295160
                     /locus_tag="Smed_3839"
                     /note="TRAP-type uncharacterized transport system,
                     periplasmic component [General function prediction only];
                     Region: Imp; COG2358"
                     /db_xref="CDD:225233"
     gene            295376..297889
                     /locus_tag="Smed_3840"
                     /db_xref="GeneID:5318568"
     CDS             295376..297889
                     /locus_tag="Smed_3840"
                     /note="TIGRFAM: TRAP transporter, 4TM/12TM fusion protein;
                     PFAM: TRAP C4-dicarboxylate transport system permease DctM
                     subunit;
                     KEGG: sme:SMb20291 hypothetical protein transmembrane"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter, 4TM/12TM fusion protein"
                     /protein_id="YP_001312585.1"
                     /db_xref="GI:150375989"
                     /db_xref="InterPro:IPR010656"
                     /db_xref="InterPro:IPR011853"
                     /db_xref="GeneID:5318568"
                     /translation="MTGLILLCTAVAWSLFQLWYASPLPFVFGFGILNDTEARAIHLG
                     FALFLTFLAYPALRSSPRDRVPLADWVLAALGAFAGAYLFIFYGDLAGRPGQPSTLDL
                     VTGTIGILLLLEATRRALGLPMVIVAGVFIFYTFAGQYMPDVIQHRGASLVKFINHQW
                     LTTEGVFGIALGVSTSFVFLFVLFGTLLEKAGAGNWMMQISIALLGHLRGGPAKVAVV
                     SSALNGVVSGSSVSNVVSGGIFTIPLMKRTGLSGVKAGAIEASASINGQIMPPVMGAA
                     AFLMVEYVGIPYSEIVKHALLPAVFSYIALLYMVHLESVKLDMQPIPQRPTPARERWI
                     RMGLGLTGSVLAVCLLYYGILGIRAAFGANAPLLLAIGGAALYIATIWYSSRYPDLEL
                     DDPNAPILELPRAWDVTRTGLDFLIPIAVLLWCLMVEQLSPGLSAFWATVTILAIVAT
                     RKPLMAIFRKEDFASSVGAAAWDLVDGLALGARNMIGIAVATATAGIVVGTITLTGLG
                     LMMTELVEFISGGNVIMMLILIAAISLVLGMGIPTTANYILVATLMAPVVVELGSQAG
                     LAIPLIAVHLFVFYFGIMADITPPVGLASFAAAAISKEDPIATGFQGALYSLRTAILP
                     FVFIFNPAILLIGVDTWAHTIWVAAISLAAILLFSAATMNWFVTKSRLWESAVLLLAC
                     FSLFRPDWWVNQISPPYEELPASEFLRTVQEAPAKARINFVVQGIDLMGDDVRKTVNV
                     PLGEPGEPLQRLRAIGLTVTPAGDSLMISNVAFGSYAKRIGLDVGYDVVAVLKKADQP
                     STAIPVSIALILTAGIAGLQFARKRADRSGASLRGTARK"
     misc_feature    295382..>296458
                     /locus_tag="Smed_3840"
                     /note="TRAP-type uncharacterized transport system, fused
                     permease components [General function prediction only];
                     Region: COG4666"
                     /db_xref="CDD:227012"
     misc_feature    <296558..297526
                     /locus_tag="Smed_3840"
                     /note="TRAP-type uncharacterized transport system, fused
                     permease components [General function prediction only];
                     Region: COG4666"
                     /db_xref="CDD:227012"
     misc_feature    297302..297856
                     /locus_tag="Smed_3840"
                     /note="Domain of unknown function (DUF3394); Region:
                     DUF3394; pfam11874"
                     /db_xref="CDD:152310"
     gene            complement(297897..298895)
                     /locus_tag="Smed_3841"
                     /db_xref="GeneID:5318569"
     CDS             complement(297897..298895)
                     /locus_tag="Smed_3841"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: sme:SMb20290 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein LacI"
                     /protein_id="YP_001312586.1"
                     /db_xref="GI:150375990"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318569"
                     /translation="MMARSTIVELARAAGVSPTTVSHAFSGRRYVDPETKARIVALAD
                     KMGYRANPRARRLRTGGAGIIALASSMPFAIAAGPARLGFLMEIAAAAAVTALSRHLA
                     LCLVPPLEPDSNLDALEVDGAIIVEPTSDDRLLEFFSARGVPVVSIGRAPGRDDIPSV
                     DIQSTATARLMLEHLGANNRRVGLITGEQRRNSYIETEAVYAAFAAENGYTPVALRVN
                     ESGGEGEAAAIAETLLRGNPDIDALCVPVDAFATGVLTAARSLNRSVPLGLRLATRYD
                     GMRAKLSVPQMTAVNLHLDQVAEAAIDLLIAVMEGKDPERRPIAPPLLVVRESSAT"
     misc_feature    complement(297903..298880)
                     /locus_tag="Smed_3841"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    complement(298719..298871)
                     /locus_tag="Smed_3841"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    complement(order(298722..298727,298731..298736,
                     298743..298745,298752..298754,298791..298793,
                     298800..298805,298818..298820,298827..298832,
                     298836..298850))
                     /locus_tag="Smed_3841"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    complement(298725..298754)
                     /locus_tag="Smed_3841"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    complement(297909..298706)
                     /locus_tag="Smed_3841"
                     /note="Ligand-binding domain of uncharacterized
                     DNA-binding regulatory proteins that are members of the
                     LacI-GalR family of bacterial transcription repressors;
                     Region: PBP1_LacI_like_8; cd06287"
                     /db_xref="CDD:107282"
     misc_feature    complement(order(298116..298121,298128..298130,
                     298140..298142,298224..298226,298539..298547,
                     298554..298556,298563..298565,298575..298577,
                     298581..298595,298614..298619,298623..298628,
                     298635..298643,298704..298706))
                     /locus_tag="Smed_3841"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:107282"
     misc_feature    complement(order(298020..298022,298071..298073,
                     298239..298241,298305..298307,298410..298412,
                     298449..298451,298518..298520,298632..298634,
                     298641..298646))
                     /locus_tag="Smed_3841"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107282"
     gene            299046..300395
                     /locus_tag="Smed_3842"
                     /db_xref="GeneID:5318570"
     CDS             299046..300395
                     /locus_tag="Smed_3842"
                     /note="PFAM: Xanthine/uracil/vitamin C permease;
                     KEGG: sme:SMb20289 putative permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/uracil/vitamin C permease"
                     /protein_id="YP_001312587.1"
                     /db_xref="GI:150375991"
                     /db_xref="InterPro:IPR005829"
                     /db_xref="InterPro:IPR006042"
                     /db_xref="InterPro:IPR006043"
                     /db_xref="GeneID:5318570"
                     /translation="MTGKKIDSIDPTDQALPPRSLILFGLQHVLVMAASPITAVFLVS
                     KALGFSDALTVSLISATFLICGLGTILQSFGPAGFGARLPFIMVPGGAPIAIFLAIAQ
                     QTDIQTAVGAVILTAGFYFLALPVFRRLLRYFPPIVVGTMLLLVSVNLVRIYGGTITG
                     KQGSEGFADPMNVGLALATIALTVIFARIFTGTFQRISVMLGLIAGSMIAFGAGYMDL
                     SGIFDGPVIAVPALLPFGMPKFDIFAALPLIVFSIISMAEATGQTIATAEIVGRRGDA
                     HAIVPATIRGDAVASLVGGLFGTSLIITSGENVGIVRATNVKSRYVTAMAGVILVLIA
                     LLAPVGRLANALPGPVVGGTAVIVFSIIGVIGIDLLRRVDLREHGPMFTLAAALSMGL
                     LPILVPGVYSQFPQWSQMILANGLAAGTITAVIVNAFFQHMPSGSAQKAAAGVEAEI"
     misc_feature    299058..300389
                     /locus_tag="Smed_3842"
                     /note="Xanthine/uracil permeases [Nucleotide transport and
                     metabolism]; Region: UraA; COG2233"
                     /db_xref="CDD:225142"
     gene            300408..301808
                     /locus_tag="Smed_3843"
                     /db_xref="GeneID:5318571"
     CDS             300408..301808
                     /locus_tag="Smed_3843"
                     /note="PFAM: amidohydrolase; Amidohydrolase 3;
                     KEGG: sme:SMb20288 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="YP_001312588.1"
                     /db_xref="GI:150375992"
                     /db_xref="InterPro:IPR000454"
                     /db_xref="InterPro:IPR006680"
                     /db_xref="InterPro:IPR013108"
                     /db_xref="GeneID:5318571"
                     /translation="MTDLRDRFLGNGDFLLHPGKVLLPEGPRSGIGIVVRKGRFSEIG
                     AAGLVGSRNPDLRPIELPHHLVMPGFIDTHTHLTQSLGKSLVFGEPSEIFRRIWVPLE
                     GSLDERMVYLSAKLAALECLRGGFTAAVDAGTRSAGHMDALIRAARETGLRSVIGLIC
                     NDLGGAAVVPDRTTILRNAAGHLAAFEGDSLVHPSLAISIPEAASDHMLADVSSMARE
                     AGVIFQTHVNEHLVAVERSLVANGRRPLEHLAHLGALGPHVLIAHSTLVTPHELNLLR
                     HSDTAVAYNPVASLWKGNAIAPALQMAALGIRFGLGTDGTRADGFRLMDAAEGLQRAG
                     FGLATGDSSCGGGWLWIDRATAQAADAAGLGCVTGAIREKLAADFLLVDLDRPEFTPS
                     HDLMWELVRYGNRDQIDAVFTAGMLRLWQGWPVQWDARALLAEVREVTADAIARAPIQ
                     RVHKPSAEHRALGHFA"
     misc_feature    300423..301682
                     /locus_tag="Smed_3843"
                     /note="Cytosine deaminase and related metal-dependent
                     hydrolases [Nucleotide transport and metabolism / General
                     function prediction only]; Region: SsnA; COG0402"
                     /db_xref="CDD:223479"
     misc_feature    300501..301682
                     /locus_tag="Smed_3843"
                     /note="Superfamily of metallo-dependent hydrolases (also
                     called amidohydrolase superfamily) is a large group of
                     proteins that show conservation in their 3-dimensional
                     fold (TIM barrel) and in details of their active site. The
                     vast majority of the members have a...; Region:
                     metallo-dependent_hydrolases; cl00281"
                     /db_xref="CDD:241750"
     misc_feature    order(300627..300629,300633..300635,301083..301085,
                     301194..301196,301347..301349)
                     /locus_tag="Smed_3843"
                     /note="active site"
                     /db_xref="CDD:238617"
     gene            301805..302512
                     /locus_tag="Smed_3844"
                     /db_xref="GeneID:5318572"
     CDS             301805..302512
                     /locus_tag="Smed_3844"
                     /note="PFAM: protein of unknown function DUF81;
                     KEGG: sme:SMb20287 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312589.1"
                     /db_xref="GI:150375993"
                     /db_xref="InterPro:IPR002781"
                     /db_xref="GeneID:5318572"
                     /translation="MTLSLFAILSAVTLVSAFIQGALGIGFALIVAPVVGILQPDLLP
                     VTLLLLMLPLNLHVAWRERSAVDWSGAKWISLGRFAGTFAGVWLLAALSSQQLDLAVG
                     WFTVIAAAAALFAPPFAPGRPSALGVGLFTGVTETATGIGGPPLALLYQHAKGPILRA
                     TVAVCFFVGEIMSLVILAIAGRIGADQLLAALYLAPAVLLGSALSRLTHDHIRGRGLR
                     LGVLIFALASGAFLIVR"
     sig_peptide     301805..301870
                     /locus_tag="Smed_3844"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.990) with cleavage site probability 0.504 at
                     residue 22"
     gene            complement(302533..303612)
                     /locus_tag="Smed_3845"
                     /db_xref="GeneID:5318573"
     CDS             complement(302533..303612)
                     /locus_tag="Smed_3845"
                     /EC_number="1.5.1.28"
                     /note="PFAM: NAD/NADP octopine/nopaline dehydrogenase;
                     6-phosphogluconate dehydrogenase NAD-binding;
                     NAD-dependent glycerol-3-phosphate dehydrogenase domain
                     protein; Ketopantoate reductase ApbA/PanE domain protein;
                     KEGG: sme:SMb20286 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="opine dehydrogenase"
                     /protein_id="YP_001312590.1"
                     /db_xref="GI:150375994"
                     /db_xref="InterPro:IPR003421"
                     /db_xref="InterPro:IPR006115"
                     /db_xref="InterPro:IPR011128"
                     /db_xref="InterPro:IPR013332"
                     /db_xref="GeneID:5318573"
                     /translation="MRIGILGAGAIAFGMAAFLAEAGHHPVLWSPSGARTRKLAEGEP
                     LTATGAVEFSGPVAIARDGREAVADVDAVVIALPANGHRMAFDAALPHLKPGQPVIVS
                     SHSSFGALYLSKRLAERGVSLPIIVWGTTLLTGRQQPDGVSVSVNTVRQKVDVATLPK
                     AAAAEGKALCSELFGDRFVERDGLLAIALSNLNPQNHLGIALLNLTRMEKGEKWGQGE
                     HVTPAVGQLIEALDAERLKIAESFGLSVRTVREHFSLSFHVPIGSVSEMNQQMHLEGR
                     GGFGPATADSRYIYEDVPFGLVPTSLLGRIAGHPAILHEAGTSLFSAAMSRDLAADNN
                     LLPDLALERLSPGALRELCDRGFTA"
     sig_peptide     complement(303553..303612)
                     /locus_tag="Smed_3845"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.977) with cleavage site probability 0.644 at
                     residue 20"
     misc_feature    complement(302632..303081)
                     /locus_tag="Smed_3845"
                     /note="NAD/NADP octopine/nopaline dehydrogenase,
                     alpha-helical domain; Region: Octopine_DH; pfam02317"
                     /db_xref="CDD:216971"
     gene            303777..304808
                     /locus_tag="Smed_3846"
                     /db_xref="GeneID:5318721"
     CDS             303777..304808
                     /locus_tag="Smed_3846"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb20285 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001312591.1"
                     /db_xref="GI:150375995"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318721"
                     /translation="MEIRELEAFLAVMSAGSITGAARLLDRSQSQVTRLIQDLETSVG
                     FSLFDRNGPKIAPSEKGIAFHAEAERFLSGIGHLRERARTIAEKEPQPIEIVAIAAFA
                     SGIIPMALAALPERLLPRKVHLRSLPAEAAVQSVLARTADFCVTSLPADQPGLEVHGV
                     FQAPCVAAVAPDDPLTAREVISIADLAGRNIITMANPFRLRSRVDKALEAANIRPARI
                     IATSVSVNAVRIASTGLGVAIVEPATAYGLKLTDVTIRPLDVDIPFLWAILSAAARPL
                     SDSSRELIQAIIRVSSACIPGFTAHDPRHANRAAEMMLGEDQTDRDARWRDYPLHNNK
                     TQNQKRRMT"
     misc_feature    303777..304643
                     /locus_tag="Smed_3846"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    303783..303959
                     /locus_tag="Smed_3846"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    304059..304607
                     /locus_tag="Smed_3846"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cl11398"
                     /db_xref="CDD:245600"
     misc_feature    order(304095..304100,304104..304109,304116..304118,
                     304128..304130,304134..304154,304428..304445,
                     304461..304466,304470..304475)
                     /locus_tag="Smed_3846"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            304805..305905
                     /locus_tag="Smed_3847"
                     /db_xref="GeneID:5318722"
     CDS             304805..305905
                     /locus_tag="Smed_3847"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb20284 putative ABC transporter periplasmic
                     spermidineputrescine-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312592.1"
                     /db_xref="GI:150375996"
                     /db_xref="InterPro:IPR001188"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5318722"
                     /translation="MKDFIASRRSTLKLLAAGTGVLAAPAIIRPAFAQSKVVNITTYD
                     KFVPQSFIDAFQKETGIEVRIRLTDDQGKQYNVLSAEGATPSSDIVTVTGHRLSQFIG
                     SNLLSPLDTGRLKNWGNLAPAYKGAPQLTVDGSVYGVPLLAGFEGLARNTDYTKASDS
                     WAIMFDKEYKGLTSYIISDFLQITMRYQGNDGDFVTYEGKPEEAQAATNKARDYLIQN
                     KDMVRKYYDAGSEVQQMFVNEDIYVAHSWSGPAAKLIMDGHPIEISVPKEGTYGFLYS
                     FNVVKNGPNTDAAYTFLDAILSSPEIGAAMSRQSGFASAFGGVDKVLNDKERAAMALP
                     QEQTERIQFFSSVNRDMKNEMVDKAVAEIKAA"
     sig_peptide     304805..304906
                     /locus_tag="Smed_3847"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 34"
     misc_feature    304823..305902
                     /locus_tag="Smed_3847"
                     /note="Spermidine/putrescine-binding periplasmic protein
                     [Amino acid transport and metabolism]; Region: PotD;
                     COG0687"
                     /db_xref="CDD:223759"
     misc_feature    304958..305731
                     /locus_tag="Smed_3847"
                     /note="ABC-type Fe3+ transport system, periplasmic
                     component [Inorganic ion transport and metabolism];
                     Region: AfuA; COG1840"
                     /db_xref="CDD:224753"
     gene            306037..307020
                     /locus_tag="Smed_3848"
                     /db_xref="GeneID:5318723"
     CDS             306037..307020
                     /locus_tag="Smed_3848"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20283 probable spermidineputrescine ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312593.1"
                     /db_xref="GI:150375997"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318723"
                     /translation="MVDTTTIRTRTAEPLRVPRYAGWIGKTVGSGLYRHTIGRLADSR
                     PVRLALLAGVPLFWIAALHIGPIFQMGRISFMADYPPSPDGGSAYTLANYKLFFSDQL
                     YFVPFLRSLVFAAVVTLSTLVVVYPVAYYVAKIVQPKNRVRALLLLLIPFWAGELIRT
                     FSVIMLLANRGAVNVALRELGFIDRPIPMLYTSFSLSFGVIYLLALYMLLPLYSAIEK
                     IPTQLVHAAADLGASPFQRFRRVILPLSKDGIVSGCSLVYLTSVGVFAAPLLLGGPNT
                     VIFPEVIATLFHSSNDKWPEGAAFSMLLLAVSLTTVGLFMRVIGGRSVRLM"
     misc_feature    <306676..306963
                     /locus_tag="Smed_3848"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(306700..306738,306754..306759,306769..306771)
                     /locus_tag="Smed_3848"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(306841..306843,306883..306885,306913..306915)
                     /locus_tag="Smed_3848"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     gene            307031..307822
                     /locus_tag="Smed_3849"
                     /db_xref="GeneID:5318724"
     CDS             307031..307822
                     /locus_tag="Smed_3849"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20282 probable spermidineputrescine ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312594.1"
                     /db_xref="GI:150375998"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318724"
                     /translation="MRPYFADLPKTALGAAYWLFAVYLLLPLALMTAMSFKDASFIAF
                     PITDWTLNWYAQVLQDKQFIEASLYSIGIALATTAAATVIGVWIALLVTTEGIWGKAI
                     IFALACLPAVVPGLINAISMRIFIRTVDIPTGTTAIILSHSVHAVPFVVIMVLTRLRS
                     MPANLVDAARDLGADPFVAFLRVTIPYLMPALLGGMIFCVLTSIDDFVRTFFLGGYKP
                     TLPMLIFAKVQGGMSPEINAMATIVLIVTAAVGLYAERLTRRSRD"
     misc_feature    307031..307816
                     /locus_tag="Smed_3849"
                     /note="ABC-type spermidine/putrescine transport system,
                     permease component II [Amino acid transport and
                     metabolism]; Region: PotC; COG1177"
                     /db_xref="CDD:224098"
     misc_feature    307322..307786
                     /locus_tag="Smed_3849"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(307325..307336,307340..307369,307376..307381,
                     307385..307387,307460..307465,307469..307471,
                     307475..307477,307484..307489,307493..307495,
                     307505..307510,307517..307519,307568..307570,
                     307610..307615,307622..307624,307643..307654,
                     307661..307666,307703..307708,307736..307741,
                     307748..307753,307757..307762,307769..307774,
                     307781..307786)
                     /locus_tag="Smed_3849"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(307343..307387,307643..307660)
                     /locus_tag="Smed_3849"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(307385..307387,307445..307447,307661..307663,
                     307697..307699,307706..307708,307736..307738)
                     /locus_tag="Smed_3849"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(307520..307558,307574..307579,307589..307591)
                     /locus_tag="Smed_3849"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            307825..308895
                     /locus_tag="Smed_3850"
                     /db_xref="GeneID:5318725"
     CDS             307825..308895
                     /locus_tag="Smed_3850"
                     /note="TIGRFAM: spermidine/putrescine ABC transporter
                     ATPase subunit;
                     PFAM: ABC transporter related; Transport-associated OB
                     domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20281 probable spermidineputrescine ABC
                     transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter ATPase"
                     /protein_id="YP_001312595.1"
                     /db_xref="GI:150375999"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005893"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5318725"
                     /translation="MQPVVQFENVNKYYGALPAVDGLNLAIEPGQFVTLLGPSGCGKS
                     TTLRMLGGFEQPSSGEIYLEGKAISHLPPNRRNVNIVFQDYALFPHLNVGRNIAFGLE
                     LKGLSSDAIHKRTMELLALVKLEDFAGRMPDQLSGGQRQRVALMRALAPDPNVLLLDE
                     PLSALDAKLRQQMQIELKTIQRTTGKTFIFVTHDQEEALTMSDVIVVMNKGRIEQMGD
                     PNELYSRPRSRFVANFIGQSNFLEGKALSVDGTVATIDWNGTAIRADVNGTQPAKDSP
                     TTVALRPEALYCLAEQPQDRFALKGRIVQRVFKGAHTALTVDLENGAQLHLQLDPVAL
                     SHIGTDEIWVGWRERDAVVLAD"
     misc_feature    307825..308892
                     /locus_tag="Smed_3850"
                     /note="ABC-type spermidine/putrescine transport systems,
                     ATPase components [Amino acid transport and metabolism];
                     Region: PotA; COG3842"
                     /db_xref="CDD:226361"
     misc_feature    307837..308532
                     /locus_tag="Smed_3850"
                     /note="ATP-binding cassette domain of the polyamine
                     transporter; Region: ABC_PotA_N; cd03300"
                     /db_xref="CDD:213267"
     misc_feature    307933..307956
                     /locus_tag="Smed_3850"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213267"
     misc_feature    order(307942..307947,307951..307959,308071..308073,
                     308299..308304,308401..308403)
                     /locus_tag="Smed_3850"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213267"
     misc_feature    308062..308073
                     /locus_tag="Smed_3850"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213267"
     misc_feature    308227..308256
                     /locus_tag="Smed_3850"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213267"
     misc_feature    308287..308304
                     /locus_tag="Smed_3850"
                     /note="Walker B; other site"
                     /db_xref="CDD:213267"
     misc_feature    308311..308322
                     /locus_tag="Smed_3850"
                     /note="D-loop; other site"
                     /db_xref="CDD:213267"
     misc_feature    308389..308409
                     /locus_tag="Smed_3850"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213267"
     misc_feature    308659..308886
                     /locus_tag="Smed_3850"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            308974..310440
                     /locus_tag="Smed_3851"
                     /db_xref="GeneID:5318726"
     CDS             308974..310440
                     /locus_tag="Smed_3851"
                     /note="KEGG: sme:SMb20280 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312596.1"
                     /db_xref="GI:150376000"
                     /db_xref="InterPro:IPR001100"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="GeneID:5318726"
                     /translation="MANERNVRLAELNARVKQDLDYLNYPAANWSKPVTMADGQPVSD
                     VVIIGGGMCGMVAWLALTRAGIANLRIVDRARKGQEGPWVTFARMETLRSPKNLLGPA
                     LGIASLTFRAWYTALHGEAAWETLFRIPRPMWMDYLNWYREVLSIPVENDTDVTRIRP
                     RDDGLVELEIAGGNQPSIITRKLVMATGREGLGEPVIPDFVKGMKRHTSWAHSADPID
                     FDALKGKRVVVIGVGASAVDNAAEALESGAGEVRLLARRKEMPTINKLMGIGSYGVTA
                     GFARIDPEWRWRIMDYSVKQQTPAPHNSTLRVSRHPNAFFHFDCSIRSMREEGGEVVL
                     TTTKGRVFRTDFVILGTGFTVDPLSRDELAPYQDRIACWEDRYTPPAGEENAGLGRFP
                     WLDDDFSFTEKEPGTAPWLKDIHCFNYGASISIGKVSGDIPAISEGALWLARGIAASL
                     FIRDVDYHWEALLAYEKPELDGSEWTDADAPQPTHRTA"
     misc_feature    309142..310437
                     /locus_tag="Smed_3851"
                     /note="Predicted flavoprotein involved in K+ transport
                     [Inorganic ion transport and metabolism]; Region: TrkA;
                     COG2072"
                     /db_xref="CDD:224983"
     misc_feature    309148..309537
                     /locus_tag="Smed_3851"
                     /note="FAD-NAD(P)-binding; Region: NAD_binding_9;
                     pfam13454"
                     /db_xref="CDD:222141"
     gene            310477..310980
                     /locus_tag="Smed_3852"
                     /db_xref="GeneID:5318727"
     CDS             310477..310980
                     /locus_tag="Smed_3852"
                     /note="KEGG: sme:SMb20279 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312597.1"
                     /db_xref="GI:150376001"
                     /db_xref="GeneID:5318727"
                     /translation="MTVSTKVDVIDAVLGLDSSSPVHALRERRAKLKHFTQTSYEAAF
                     TPSDPGNFSFAMRAALAARMAGLWRSAELQAHYKELLEERGSTPGLQAIADPGVVPEG
                     DERLATILAHVDLVTLKPREATRANIEALYAVGLDDRDIVTLAGLIAFVNYQVLVVAG
                     VKMLRDN"
     misc_feature    310477..310977
                     /locus_tag="Smed_3852"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4950; cl17731"
                     /db_xref="CDD:248285"
     gene            310982..311560
                     /locus_tag="Smed_3853"
                     /db_xref="GeneID:5318728"
     CDS             310982..311560
                     /locus_tag="Smed_3853"
                     /note="TIGRFAM: uncharacterized peroxidase-related enzyme;
                     PFAM: Carboxymuconolactone decarboxylase;
                     KEGG: sme:SMb20278 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxidase-like protein"
                     /protein_id="YP_001312598.1"
                     /db_xref="GI:150376002"
                     /db_xref="InterPro:IPR003779"
                     /db_xref="InterPro:IPR010195"
                     /db_xref="GeneID:5318728"
                     /translation="MSEAVHEFTLEPLDWQPYVRPVKLDEATTEQLEALKVTPSNTKV
                     SNYVLVLANEAEMLAERTPLFNDIMYSEGGLSRGGREIGALAASFVNRCIYCASVHAN
                     RYIQLEKRPEVVDEIYRRGLDADLPDFEQALFNFGADLTAHPDNVGVYQFYHLREIGL
                     DDLEILDLIHSIAIFGWANRLMHTLGEPHLKA"
     misc_feature    311003..311545
                     /locus_tag="Smed_3853"
                     /note="Carboxymuconolactone decarboxylase family; Region:
                     CMD; cl00460"
                     /db_xref="CDD:241878"
     misc_feature    311030..311548
                     /locus_tag="Smed_3853"
                     /note="uncharacterized peroxidase-related enzyme; Region:
                     peroxid_rel; TIGR01926"
                     /db_xref="CDD:130981"
     gene            complement(311627..312970)
                     /locus_tag="Smed_3854"
                     /db_xref="GeneID:5318729"
     CDS             complement(311627..312970)
                     /locus_tag="Smed_3854"
                     /note="PFAM: aminotransferase class-III;
                     KEGG: sme:SMb20277 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312599.1"
                     /db_xref="GI:150376003"
                     /db_xref="InterPro:IPR005814"
                     /db_xref="GeneID:5318729"
                     /translation="MTHLLHRAIHAKLPVAVRGEGVRLFDAEGRAYIDASGGAAVSCL
                     GHAHPDVLAALHAQLDRMAYAHTGFFTTEAAERLADRLVADAPDGLDHVYLVSGGSEA
                     IEAALKMARQYFVEKGEPQRRHIIARRQSYHGNTLGALAAGGNEWRRAQFRPLLVETH
                     HIDPCFAYRLQQSGESDADYAARAAGQLEAKILELGADQVIAFVAETVVGATAGAVPP
                     VADYLKRVRAICDKYGVLLILDEVMCGMGRTGTLHACEQDGVVPDLMTIAKGLGGGYQ
                     PVGAVLLSSAIFQAFAEGSGFFQHGHTYMAHPMAAAAGLAVQEIIRRDGLLQNVVTMG
                     DYLETCLVERLGNHHHVGDIRGRGLFRAIELVADRAVKFPFDPGLKLNGRIKKEAMAR
                     GLMVYPMGGTIDGQRGDHVLLAPPFILTREDVDQIVERLGDAVDAAIASLSRAAG"
     misc_feature    complement(311642..312970)
                     /locus_tag="Smed_3854"
                     /note="hypothetical protein; Provisional; Region:
                     PRK07483"
                     /db_xref="CDD:236027"
     misc_feature    complement(311666..312964)
                     /locus_tag="Smed_3854"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     Region: OAT_like; cd00610"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(312164..312166,312242..312247,
                     312251..312253,312350..312352,312566..312568,
                     312572..312577,312671..312679))
                     /locus_tag="Smed_3854"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(312164..312166,312242..312244,
                     312251..312253,312350..312352,312572..312577,
                     312671..312676))
                     /locus_tag="Smed_3854"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99735"
     misc_feature    complement(312164..312166)
                     /locus_tag="Smed_3854"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     gene            complement(312967..313857)
                     /locus_tag="Smed_3855"
                     /db_xref="GeneID:5318730"
     CDS             complement(312967..313857)
                     /locus_tag="Smed_3855"
                     /note="PFAM: helix-turn-helix protein RpiR; sugar
                     isomerase (SIS);
                     KEGG: sme:SMb20276 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RpiR family transcriptional regulator"
                     /protein_id="YP_001312600.1"
                     /db_xref="GI:150376004"
                     /db_xref="InterPro:IPR000281"
                     /db_xref="InterPro:IPR001347"
                     /db_xref="GeneID:5318730"
                     /translation="MDKGPLSDRIITAFDGLSTQLQTAARYVVDHPREVALLSMREQA
                     RRAGVQPASMTRLAKHLGFDGYDELRDRYAEALREGDSGFAERAGEQARSQKLKGDHA
                     LAADMLGSIGKQISRLSEPASLDRIVEAATRLAGARRVYCLGLRSSHAVAWQVHYILS
                     LVGEKSVILDGIAGTGADAIGRAGAADVLLVASVLPYTRATIELAEYARASGVPIVAV
                     TDSEVAPLAQIAEAIIIVPTESPSFLHAMTPAFAIAEVLGALVAGRGGEAALQALKRF
                     DGQLAALDTHLQTRNSKRAS"
     misc_feature    complement(313003..313842)
                     /locus_tag="Smed_3855"
                     /note="Transcriptional regulators [Transcription]; Region:
                     RpiR; COG1737"
                     /db_xref="CDD:224651"
     misc_feature    complement(313627..313833)
                     /locus_tag="Smed_3855"
                     /note="Helix-turn-helix domain, rpiR family; Region:
                     HTH_6; pfam01418"
                     /db_xref="CDD:201784"
     misc_feature    complement(313087..313485)
                     /locus_tag="Smed_3855"
                     /note="RpiR-like protein. RpiR contains a SIS (Sugar
                     ISomerase) domain, which is found in many phosphosugar
                     isomerases and phosphosugar binding proteins. In E. coli,
                     rpiR negatively regulates the expression of rpiB gene.
                     Both rpiB and rpiA are ribose phosphate...; Region:
                     SIS_RpiR; cd05013"
                     /db_xref="CDD:240144"
     misc_feature    complement(order(313279..313281,313414..313416))
                     /locus_tag="Smed_3855"
                     /note="putative active site [active]"
                     /db_xref="CDD:240144"
     gene            313948..314805
                     /locus_tag="Smed_3856"
                     /db_xref="GeneID:5318293"
     CDS             313948..314805
                     /locus_tag="Smed_3856"
                     /note="PFAM: protein of unknown function DUF849;
                     KEGG: sme:SMb20275 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312601.1"
                     /db_xref="GI:150376005"
                     /db_xref="InterPro:IPR008567"
                     /db_xref="GeneID:5318293"
                     /translation="MSVDALQGVSITVAPNGGRRTKADHPAIPLTPEELARTARDCLE
                     AGAAMIHVHVRKADGSHLLDAEAYRAAITAIRKAVGKRLVIQMTSEALGIYSPAEQIA
                     VVRSVRPQAASLALRELVPDEAHEAAFADLLSWAARQEVMPQIILYSPEEAVRLADMR
                     RRGLLSRDDIPVLYVLGRYTPGQTSLPRDLLTFLAPEMPVFAHWSVCAFGRHEAACVT
                     AAALAGGHVRVGFENNLRLPDGTPSGSNADLVRAVTAVLRPLSIPLIDGPALADMLSR
                     IGAAGMHRD"
     misc_feature    313960..314784
                     /locus_tag="Smed_3856"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3246"
                     /db_xref="CDD:225785"
     gene            314970..315155
                     /locus_tag="Smed_3857"
                     /db_xref="GeneID:5318294"
     CDS             314970..315155
                     /locus_tag="Smed_3857"
                     /note="KEGG: sme:SMb20274 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312602.1"
                     /db_xref="GI:150376006"
                     /db_xref="GeneID:5318294"
                     /translation="MVTHDNSNMPERRATPAFPIGLILLAICAIFAYLAIGGALLESE
                     TETVVYTPPAADAPEPR"
     gene            315409..315597
                     /locus_tag="Smed_3858"
                     /db_xref="GeneID:5318295"
     CDS             315409..315597
                     /locus_tag="Smed_3858"
                     /note="KEGG: sme:SMb20273 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312603.1"
                     /db_xref="GI:150376007"
                     /db_xref="GeneID:5318295"
                     /translation="MTHAEEVIERAMAAVAQARRRREREQEWRRQTFGRIQVGMPLPP
                     LKRGGVQLSLQLERPNAR"
     gene            complement(315667..316875)
                     /locus_tag="Smed_3859"
                     /db_xref="GeneID:5318296"
     CDS             complement(315667..316875)
                     /locus_tag="Smed_3859"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: sme:SMb20272 putative transporter protein"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001312604.1"
                     /db_xref="GI:150376008"
                     /db_xref="InterPro:IPR003006"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5318296"
                     /translation="MISSHYRWVIVAAGGLLGCIAIGAMFSLPVFLVPISRDTGWSVT
                     GISSAMTVGFLAMALASMVWGSASDRWGPRPVVLIGSALLASSLALSSFVTSLIAFQL
                     IFGVFVGGACAAIFAPMMACVTGWFDTHRSLAVSLVSAGMGMAPMTMSPLAGWLITIY
                     DWRTSLQIIAAIAAVTMIPAAMLLRRPPVLEDPNAGPASEGQPDMSLGQALRSPQFVI
                     LLLTNFFCCATHSGPIFHTVSYAVSCGIPMMAAVSIYSLEGLAGMGGRVAFGILGDRY
                     GAKRILVSGLLLQAFGALAYFFVRDLGAFYAVAALFGFIYAGVMPLYAVIARENFPLR
                     MMGTVIGGTAMAGSLGMAIGPVAGGVIYDVFASYGWLYIGAWGIGIGAFLIALTFKPF
                     PKRRPAAAAA"
     sig_peptide     complement(316777..316875)
                     /locus_tag="Smed_3859"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.861) with cleavage site probability 0.786 at
                     residue 33"
     misc_feature    complement(315715..316803)
                     /locus_tag="Smed_3859"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(315811..316803)
                     /locus_tag="Smed_3859"
                     /note="Major Facilitator Superfamily; Region: MFS_1;
                     pfam07690"
                     /db_xref="CDD:219516"
     misc_feature    complement(order(315823..315825,315832..315837,
                     315844..315849,315856..315861,315892..315894,
                     315901..315906,315916..315918,315925..315930,
                     315937..315939,316078..316080,316090..316092,
                     316099..316101,316111..316113,316123..316125,
                     316162..316164,316171..316176,316183..316188,
                     316195..316197,316438..316440,316456..316461,
                     316468..316473,316504..316506,316513..316518,
                     316525..316530,316537..316542,316681..316686,
                     316690..316695,316705..316707,316714..316719,
                     316726..316728,316777..316782,316786..316794,
                     316801..316803))
                     /locus_tag="Smed_3859"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(317093..317524)
                     /locus_tag="Smed_3860"
                     /db_xref="GeneID:5318297"
     CDS             complement(317093..317524)
                     /locus_tag="Smed_3860"
                     /note="PFAM: OsmC family protein;
                     KEGG: sme:SMb20271 putative redox protein"
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="YP_001312605.1"
                     /db_xref="GI:150376009"
                     /db_xref="InterPro:IPR003718"
                     /db_xref="GeneID:5318297"
                     /translation="MKARIKWVEGRTFVGESGSGHKVVLGTATGPDGPTPGPSPMEMV
                     LIGTGGCSAFDVVHILEKGREAIEDCVVELDADRAEQDPRVFTRIHMHFIVKGRGLAA
                     KKVERAVALSIEKYCSASAMLAKTATITHDFEVVDTSIMAG"
     misc_feature    complement(317114..317524)
                     /locus_tag="Smed_3860"
                     /note="OsmC-like protein; Region: OsmC; cl00767"
                     /db_xref="CDD:242076"
     gene            complement(317602..318630)
                     /locus_tag="Smed_3861"
                     /db_xref="GeneID:5318298"
     CDS             complement(317602..318630)
                     /locus_tag="Smed_3861"
                     /note="PFAM: proline racemase;
                     KEGG: sme:SMb20270 putative proline racemase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="YP_001312606.1"
                     /db_xref="GI:150376010"
                     /db_xref="InterPro:IPR008794"
                     /db_xref="GeneID:5318298"
                     /translation="MRSTKTIHVISAHAEGEVGDVIVGGVTPPPGDTIWEQSRWIAGD
                     QTLRNFVLNEPRGGVFRHVNLLVPPKNPEADAAFIIMEPEDTPPMSGSNSICVSTVLL
                     DSGILPMKEPVTEITLEAPGGLVRVRAECRDGKAERIFVQNLPSFADRLDAKLEVEGL
                     GTLTVDAAYGGDSFVVLDAAAMGFSLKPDEAHDIARLGVRITNAANAQLGFHHPENPD
                     WRHFSFCLFAGPVERTAEGLRAGAAVAIQPGKVDRSPTGTALSARMAVLHARGEMGLS
                     DRLTAVSLIGSTFSGRILGTTEVGGRPAVLPEISGRGWITGTHQHMLDPSDPWPEGYR
                     LSDTWGAR"
     misc_feature    complement(317605..318630)
                     /locus_tag="Smed_3861"
                     /note="Proline racemase [Amino acid transport and
                     metabolism]; Region: COG3938"
                     /db_xref="CDD:226448"
     misc_feature    complement(317626..318471)
                     /locus_tag="Smed_3861"
                     /note="hydroxyproline-2-epimerase; Provisional; Region:
                     PRK13971"
                     /db_xref="CDD:184428"
     gene            complement(318693..320384)
                     /locus_tag="Smed_3862"
                     /db_xref="GeneID:5318299"
     CDS             complement(318693..320384)
                     /locus_tag="Smed_3862"
                     /note="PFAM: protein of unknown function DUF126; protein
                     of unknown function DUF521;
                     KEGG: sme:SMb20269 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312607.1"
                     /db_xref="GI:150376011"
                     /db_xref="InterPro:IPR002840"
                     /db_xref="InterPro:IPR007506"
                     /db_xref="GeneID:5318299"
                     /translation="MSALERARSILQGSAEGPVIHMAEALSFWGGVDPDTGCVIDVHH
                     PQHGVSLTGAILMMPSSRGSCTGSGVLLDLLLTGRGPAALVFSQPEDVLTLGALVAFE
                     MFGKPLPVLRLGPEAFAALAGAKTARIGSTAIEAEGLTLPVVPPATAALGLTEADRSM
                     LDGEDGVVVQQAMRIITAMAAQQGAQGLVDVVQAHIDGCIYASPANLTFAEKMADMGA
                     KVRVPTTMNAISVDRDNWRTQGVPESFGGPAARLADAYVRMGCRPTFTCSPYLLDSAP
                     VPGEAIAWAESNAVIFANSVLGARTAKHPDFLDLCIALTGRAPLSGVYLDAHRRARRV
                     IDVELPDGVDDAFWPLIGYLAGRAAPDRIPLLCGLAPARPSRDDLKALCAAFGTTSAA
                     PMLHVEGVTPEADGAAAEGADRLAIKRAEMIAAWSALNGGPEEVELVAIGSPHASLTE
                     CRALADALDGRRRHPDVAVIVTAGHEVIAKAQHEGTLTRLEESGVQVLPDLCWCSISE
                     PVFPARTRAVMTNSGKYAHYGPGLSGRAVRFGSLADCVAVALTGRVAPRLPDWLS"
     misc_feature    complement(320043..320357)
                     /locus_tag="Smed_3862"
                     /note="Putative Aconitase X swivel domain. It is predicted
                     by comparative genomic analysis. The proteins are mainly
                     found in archaea and proteobacteria. They are distantly
                     related to Aconitase family of proteins by sequence
                     similarity and seconary structure...; Region: AcnX_swivel;
                     cd01356"
                     /db_xref="CDD:238658"
     misc_feature    complement(320187..320195)
                     /locus_tag="Smed_3862"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238658"
     misc_feature    complement(318741..319928)
                     /locus_tag="Smed_3862"
                     /note="Protein of unknown function (DUF521); Region:
                     DUF521; pfam04412"
                     /db_xref="CDD:218073"
     misc_feature    complement(318738..319913)
                     /locus_tag="Smed_3862"
                     /note="Putative Aconitase X catalytic domain; Region:
                     AcnX; cd01355"
                     /db_xref="CDD:153130"
     misc_feature    complement(order(318813..318815,318828..318830,
                     318864..318866,319524..319529,319890..319892,
                     319899..319901))
                     /locus_tag="Smed_3862"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:153130"
     misc_feature    complement(order(318831..318833,318864..318869,
                     318879..318881,319056..319058,319521..319523))
                     /locus_tag="Smed_3862"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:153130"
     gene            complement(320381..321382)
                     /locus_tag="Smed_3863"
                     /db_xref="GeneID:5318300"
     CDS             complement(320381..321382)
                     /locus_tag="Smed_3863"
                     /note="PFAM: proline racemase;
                     KEGG: sme:SMb20268 putative proline racemase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyproline-2-epimerase"
                     /protein_id="YP_001312608.1"
                     /db_xref="GI:150376012"
                     /db_xref="InterPro:IPR008794"
                     /db_xref="GeneID:5318300"
                     /translation="MATHTFSCIDGHTCGNPVRLVSGGGPRLEGANMLEKRAHFLKEF
                     DWIRTGLMFEPRGHDMMSGSILYPPTRPDCDVAVLFIETSGCLPMCGHGTIGTITMGI
                     ENGLITPREPGRLSIDAPAGKVDITYRQEGRFVEEVRLTNVPGFLYAEGLTAEVEGLG
                     EIVVDVAYGGNFYAIVEPQKNFRDMADHTAGELVGWSPKLRAALNEKYEFVHPEHPEI
                     RGLSHIQWTGKPTQSEAHARNAVFYGEKAIDRSPCGTGTSARMAQLAAKGKLKVGDEF
                     VHESIIGSLFKGRVEAAAKVADRDAIIPSIAGWARMTGINTIFIDDRDPFAHGFVVK"
     misc_feature    complement(320384..321382)
                     /locus_tag="Smed_3863"
                     /note="hydroxyproline-2-epimerase; Provisional; Region:
                     PRK13971"
                     /db_xref="CDD:184428"
     misc_feature    complement(320387..321382)
                     /locus_tag="Smed_3863"
                     /note="Proline racemase [Amino acid transport and
                     metabolism]; Region: COG3938"
                     /db_xref="CDD:226448"
     gene            complement(321397..322638)
                     /locus_tag="Smed_3864"
                     /db_xref="GeneID:5318301"
     CDS             complement(321397..322638)
                     /locus_tag="Smed_3864"
                     /EC_number="1.4.99.1"
                     /note="PFAM: FAD dependent oxidoreductase;
                     KEGG: sme:SMb20267 putative D-amino acid dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino-acid dehydrogenase"
                     /protein_id="YP_001312609.1"
                     /db_xref="GI:150376013"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="GeneID:5318301"
                     /translation="MAEPDVIVIGAGVVGLSAAIAAVGRGLSVTVLDREGPAAGASAG
                     NAGAFAFTDILPLASPGILRKAPKWLLDPLGPLTVPPAYALKIAPWMFRFWRACQPGR
                     VAHSTAAQTALMDLSKAELEPFLKETGTASMLRKEGNLQVYEGEAEFKASLAGWKARE
                     DHGIEFHHLDAAAMSGIQPGLAARFTHGTFTPGWYSIADPKLYTLALADHFRTIGGKV
                     QRAEVTALRPVDGGVDVLTTDGEIQRAAQVVLSAGAFSHRIARTIGESIPLETERGYN
                     TTLPAGAFDLRTQITFGGHGFVVTRLSTGIRVGGAVELGGLDLPPNFHRSEAMLKKAQ
                     GFLPGLKPEGGVQWMGFRPSLPDSLPAIGRAVATPRVVYAFGHGHLGLTQSAGTARIV
                     ADLLTGRQPAIDIASFSPQRF"
     misc_feature    complement(321400..322623)
                     /locus_tag="Smed_3864"
                     /note="D-amino acid dehydrogenase small subunit;
                     Validated; Region: PRK00711"
                     /db_xref="CDD:234819"
     misc_feature    complement(<322537..>322623)
                     /locus_tag="Smed_3864"
                     /note="Formate/glycerate dehydrogenases, D-specific
                     2-hydroxy acid dehydrogenases and related dehydrogenases;
                     Region: FDH_GDH_like; cl17240"
                     /db_xref="CDD:247794"
     misc_feature    complement(order(322537..322545,322597..322599,
                     322603..322611))
                     /locus_tag="Smed_3864"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:240631"
     misc_feature    complement(<321838..>322158)
                     /locus_tag="Smed_3864"
                     /note="hydroxyglutarate oxidase; Provisional; Region:
                     PRK11728"
                     /db_xref="CDD:183292"
     gene            complement(322639..323361)
                     /locus_tag="Smed_3865"
                     /db_xref="GeneID:5318864"
     CDS             complement(322639..323361)
                     /locus_tag="Smed_3865"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20266 putative amino acid ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312610.1"
                     /db_xref="GI:150376014"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318864"
                     /translation="MIEIENVRKSFSSLEVLKGINLTVDKGEVVTIIGGSGSGKSTLL
                     TCINGLEPIDSGRIRIDGTDVHAKGTDLNKLRRKVGIVFQQWNAFPHLTVLENVMLAP
                     RKVLGLAKDKAEEIAVKQLTHVGLAEKLKVYPNRMSGGQQQRMAIARALAMSPEYMLF
                     DEVTSALDPMLVGEVLDTLKMLAEEGMTMICVTHEMAFARDVSDRVAFFHQGVMAEIG
                     TPDQIFAMPQNAETQKFLASVR"
     misc_feature    complement(322642..323361)
                     /locus_tag="Smed_3865"
                     /note="ABC-type polar amino acid transport system, ATPase
                     component [Amino acid transport and metabolism]; Region:
                     GlnQ; COG1126"
                     /db_xref="CDD:224051"
     misc_feature    complement(322723..323358)
                     /locus_tag="Smed_3865"
                     /note="ATP-binding cassette domain of the histidine and
                     glutamine transporters; Region: ABC_HisP_GlnQ; cd03262"
                     /db_xref="CDD:213229"
     misc_feature    complement(323239..323262)
                     /locus_tag="Smed_3865"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(order(322780..322782,322876..322881,
                     323110..323112,323236..323244,323248..323253))
                     /locus_tag="Smed_3865"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(323110..323121)
                     /locus_tag="Smed_3865"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(322924..322953)
                     /locus_tag="Smed_3865"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(322876..322893)
                     /locus_tag="Smed_3865"
                     /note="Walker B; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(322858..322869)
                     /locus_tag="Smed_3865"
                     /note="D-loop; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(322774..322794)
                     /locus_tag="Smed_3865"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213229"
     gene            complement(323354..324007)
                     /locus_tag="Smed_3866"
                     /db_xref="GeneID:5318865"
     CDS             complement(323354..324007)
                     /locus_tag="Smed_3866"
                     /note="TIGRFAM: polar amino acid ABC transporter, inner
                     membrane subunit;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb20265 putative amino acid ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polar amino acid ABC transporter inner membrane
                     subunit"
                     /protein_id="YP_001312611.1"
                     /db_xref="GI:150376015"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR010065"
                     /db_xref="GeneID:5318865"
                     /translation="MFNTALTWNDLAFLAQGAGMTLAVTAVAVTAGTLLGILFGVIRF
                     QLGPYWAAPLTLLLDVFRSVPLLIQLVLGSAFQSIVKLGWGAFTTSGVVLSLYTAAFC
                     AEIVRGGISSVPVTTRRAARSLGMTWWQDMRYIVAPLATRVSLPSWIGLTLGVMKDSA
                     LVLWLGLVELLRASQILVTRLQEPLFILLICGAIYFLLSFPVARFGGYLEKRWSPND"
     sig_peptide     complement(323921..324007)
                     /locus_tag="Smed_3866"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.967) with cleavage site probability 0.628 at
                     residue 29"
     misc_feature    complement(323408..323899)
                     /locus_tag="Smed_3866"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(323408..323413,323420..323425,
                     323429..323434,323441..323446,323474..323479,
                     323516..323521,323528..323539,323558..323560,
                     323567..323572,323612..323614,323663..323665,
                     323672..323677,323687..323689,323693..323698,
                     323705..323707,323711..323713,323717..323722,
                     323795..323797,323804..323833,323837..323848,
                     323876..323878,323891..323896))
                     /locus_tag="Smed_3866"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(323522..323539,323795..323800,
                     323801..323830))
                     /locus_tag="Smed_3866"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(323444..323446,323474..323476,
                     323483..323485,323519..323521,323735..323737,
                     323795..323797))
                     /locus_tag="Smed_3866"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(323591..323593,323603..323608,
                     323624..323662))
                     /locus_tag="Smed_3866"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(324018..324683)
                     /locus_tag="Smed_3867"
                     /db_xref="GeneID:5318866"
     CDS             complement(324018..324683)
                     /locus_tag="Smed_3867"
                     /note="TIGRFAM: polar amino acid ABC transporter, inner
                     membrane subunit;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb20264 putative amino acid ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polar amino acid ABC transporter inner membrane
                     subunit"
                     /protein_id="YP_001312612.1"
                     /db_xref="GI:150376016"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR010065"
                     /db_xref="GeneID:5318866"
                     /translation="MFNYTFHWNQALRALPQMLDGAVVTLQVAVLSMVIGVACAIALT
                     VFRLSGSRILGGIATTWVEVARNTPALFQIYMAHFGLGNFGIHLSPYTALLVGIAFNN
                     AGYLAENFRGALKAIPDTQARAGRSLGMTSLQAFRLIVLPQMLRVAFLPATNQMVWAI
                     LMTSLGVTVGMNTDLAGITQELNARSFRTFEFFALAAVIYYLIAKAVTLAARAFAWRM
                     FRY"
     misc_feature    complement(324024..324638)
                     /locus_tag="Smed_3867"
                     /note="ABC-type arginine transport system, permease
                     component [Amino acid transport and metabolism]; Region:
                     ArtQ; COG4215"
                     /db_xref="CDD:226670"
     misc_feature    complement(324057..324620)
                     /locus_tag="Smed_3867"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(324057..324062,324069..324074,
                     324081..324086,324090..324095,324102..324107,
                     324135..324140,324180..324185,324192..324203,
                     324222..324224,324231..324236,324276..324278,
                     324327..324329,324336..324341,324351..324353,
                     324357..324362,324369..324371,324375..324377,
                     324381..324386,324450..324452,324456..324461,
                     324468..324497,324501..324512,324540..324542,
                     324555..324560,324567..324572))
                     /locus_tag="Smed_3867"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(324186..324203,324450..324494))
                     /locus_tag="Smed_3867"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(324105..324107,324135..324137,
                     324144..324146,324183..324185,324390..324392,
                     324450..324452))
                     /locus_tag="Smed_3867"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(324255..324257,324267..324272,
                     324288..324326))
                     /locus_tag="Smed_3867"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(324750..325556)
                     /locus_tag="Smed_3868"
                     /db_xref="GeneID:5318867"
     CDS             complement(324750..325556)
                     /locus_tag="Smed_3868"
                     /note="PFAM: extracellular solute-binding protein family
                     3;
                     KEGG: sme:SMb20263 putative ABC transporter periplasmic
                     amino acid-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312613.1"
                     /db_xref="GI:150376017"
                     /db_xref="InterPro:IPR001638"
                     /db_xref="GeneID:5318867"
                     /translation="MKTSILAFGLVAATALTSPAHADKLDDIIASGTLRCAVVLDFPP
                     MGSRDENNEPIGFDVDYCNDLAKALGVTAEIVETPFPERIPALMSGRVDVGVASTSDT
                     LERAKTVGMTVPYFAFEMAVTANEKSGIKSFEDMKGKVVGATAGTYEAIALENQVKAW
                     GEGEFRPYQTQADVFLALSQGQLDATVSTSTVAQSNVKGGKFPGISVVDKAPFDIDYV
                     ALFTNREEYGFINYLNLFVNQQVRTGRYAELYEKWVGGEAPSLAVNGVYR"
     sig_peptide     complement(325488..325556)
                     /locus_tag="Smed_3868"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 23"
     misc_feature    complement(324792..325457)
                     /locus_tag="Smed_3868"
                     /note="Bacterial extracellular solute-binding proteins,
                     family 3; Region: SBP_bac_3; pfam00497"
                     /db_xref="CDD:215950"
     misc_feature    complement(324798..325457)
                     /locus_tag="Smed_3868"
                     /note="Bacterial periplasmic transport systems use
                     membrane-bound complexes and substrate-bound,
                     membrane-associated, periplasmic binding proteins (PBPs)
                     to transport a wide variety of  substrates, such as, amino
                     acids, peptides, sugars, vitamins and inorganic...;
                     Region: PBPb; cd00134"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(324990..324992,325116..325118,
                     325242..325244,325317..325319,325431..325433))
                     /locus_tag="Smed_3868"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(325011..325013,325029..325031,
                     325041..325043))
                     /locus_tag="Smed_3868"
                     /note="membrane-bound complex binding site; other site"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(324900..324902,324903..324914))
                     /locus_tag="Smed_3868"
                     /note="hinge residues; other site"
                     /db_xref="CDD:238078"
     gene            complement(325740..327257)
                     /locus_tag="Smed_3869"
                     /db_xref="GeneID:5318868"
     CDS             complement(325740..327257)
                     /locus_tag="Smed_3869"
                     /note="PFAM: aldehyde dehydrogenase;
                     KEGG: sme:SMb20262 putative semialdehyde dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="YP_001312614.1"
                     /db_xref="GI:150376018"
                     /db_xref="InterPro:IPR002086"
                     /db_xref="GeneID:5318868"
                     /translation="MVFTPKGKHLVAGEWLDGAGTFASAPAHGPAHDFAVGTVELVNR
                     ACDAAEEAFWSYGYSSRKERAAFLRAIADEIEARAEAITDIGSQETGLPEARLNGERG
                     RTTGQLRLFADHIEKGDYLDRRVDAALPDRQPAPRQEIRLIQRPVGPVAVFGASNFPL
                     AFSTAGGDTAAALAAGCPVVVKGHSAHPGTGEIVAEAIDAAIRKTGVHPGVFSLIQGG
                     SRDVGHALVQHPNIKAVGFTGSLAGGRALFDLCAARPEPIPFFGELGSVNPMFLLPEA
                     LKARAEALGQGWAGSLTMGAGQFCTNPGIAVVIEGTDADRFTTTAAEALAKVAPQTML
                     TDGIAKAYRDGQERFATRNAVKPLLATESSGRDASPNLFETTGEQFLSDHALGEEVFG
                     PLGLVIRVGSPAEMEELARGFAGQLTATIHMDAGDLETARRLRPVLERKAGRVLVNGF
                     PTGVEVVDSMVHGGPYPASTNFGATSVGTMSIRRFLRPVAYQNMPEDLLPEDFLA"
     misc_feature    complement(325764..327236)
                     /locus_tag="Smed_3869"
                     /note="NAD-dependent aldehyde dehydrogenases [Energy
                     production and conversion]; Region: PutA; COG1012"
                     /db_xref="CDD:223944"
     misc_feature    complement(325779..327134)
                     /locus_tag="Smed_3869"
                     /note="Alpha-Ketoglutaric Semialdehyde Dehydrogenase;
                     Region: ALDH_KGSADH; cd07129"
                     /db_xref="CDD:143447"
     misc_feature    complement(order(325782..325793,325797..325802,
                     325860..325865,325875..325880,325893..325895,
                     325917..325919,325923..325934,325938..325940,
                     325950..325952,325962..325964,326025..326027,
                     326514..326516,326523..326525,326832..326834,
                     326838..326840,326880..326882,327084..327086,
                     327096..327098))
                     /locus_tag="Smed_3869"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143447"
     misc_feature    complement(order(326529..326531,326538..326540,
                     326547..326549,326586..326588,326703..326708,
                     326712..326714,326790..326792))
                     /locus_tag="Smed_3869"
                     /note="NADP binding site [chemical binding]; other site"
                     /db_xref="CDD:143447"
     misc_feature    complement(order(326358..326360,326367..326369,
                     326469..326471,326787..326789))
                     /locus_tag="Smed_3869"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143447"
     gene            327573..328610
                     /locus_tag="Smed_3870"
                     /db_xref="GeneID:5318869"
     CDS             327573..328610
                     /locus_tag="Smed_3870"
                     /note="PFAM: Malate/L-lactate dehydrogenase;
                     KEGG: sme:SMb20261 putative malate dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="malate/L-lactate dehydrogenase"
                     /protein_id="YP_001312615.1"
                     /db_xref="GI:150376019"
                     /db_xref="InterPro:IPR003767"
                     /db_xref="GeneID:5318869"
                     /translation="MSETTTLTTTALHERVEAIFRKGGLNVVQAGALARVIVAGERDA
                     CKSHGIYRIEGALRTVKAGKVKPDAIPEIIAQEASAIVKVNAGGGFANPAFELGLPVL
                     AERARTQGIAALAINDCTHFSALWPEAEALTGEGLAGLVMCPSYATVAPTGGNKPLLG
                     TNPFAFGWPRAGRPPYVFDFATSVAARGEIELHRRAGKALPDGWAIDAKGNPTTDPEA
                     ALAGAMLPFGGHKGSAIGTMIELLAGIMIGDLTSPEVLDYLGTTTLAPFHGELIIAFS
                     PEAFAAGRPGDPFARAEMLFEAIVGQGARLPSQRRFAARAKSEAEGITLTAAEVEQLD
                     RLLTLGLDAVA"
     misc_feature    327603..328604
                     /locus_tag="Smed_3870"
                     /note="Malate/L-lactate dehydrogenases [Energy production
                     and conversion]; Region: COG2055"
                     /db_xref="CDD:224966"
     gene            328762..329139
                     /locus_tag="Smed_3871"
                     /db_xref="GeneID:5318870"
     CDS             328762..329139
                     /locus_tag="Smed_3871"
                     /note="PFAM: protein of unknown function DUF1232;
                     KEGG: sme:SMb20260 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312616.1"
                     /db_xref="GI:150376020"
                     /db_xref="InterPro:IPR010652"
                     /db_xref="GeneID:5318870"
                     /translation="MNRLDRARRWARDIKRDVIVLWLAARDSRVPWYAKLAAGAIAAY
                     ALSPVDLIPDFIPILGYLDDLVIVPLGIIAVLRLIPTDVLAELRIEALKQVERPVSRA
                     GMAAVISIWLIFVALISWMALAP"
     misc_feature    328762..329046
                     /locus_tag="Smed_3871"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3339"
                     /db_xref="CDD:225876"
     gene            329189..330229
                     /locus_tag="Smed_3872"
                     /db_xref="GeneID:5318871"
     CDS             329189..330229
                     /locus_tag="Smed_3872"
                     /note="PFAM: peptidase C45 acyl-coenzyme
                     A:6-aminopenicillanic acid acyl-transferase;
                     KEGG: sme:SMb20028 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C45 acyl-coenzyme
                     A:6-aminopenicillanic acid acyl-transferase"
                     /protein_id="YP_001312617.1"
                     /db_xref="GI:150376021"
                     /db_xref="InterPro:IPR005079"
                     /db_xref="GeneID:5318871"
                     /translation="MSALPRKRFRSYTPRVMYKTFVAAREDRPGEAWLSRFAAGRAEA
                     ERWYFGQAPMAASPSAKECRAALMQHMPELVPHYESACDLVGDDEIAHRLLSHYRPAP
                     ERYGCSQSVWLGKEGPALIRNFDYPPDIVSDRFEMTDWSGVKVIAKMQRPWGGCVDGL
                     NEEGLAASVTLGGGRSQGLGFSIILVMRYLLENFREVGEAVKALCRIPVALAQNVTVL
                     DRAGSYATLFLGPGQRPVITRLKACTNHQRGGRPSSSSLARQQFVLQALEDPSMSLEK
                     LTDRFLQPPLYSMRLPQPTLYTAVYRPAEGRVDYIWPGNHWSQGFDGFETGEYTHRYG
                     SSGGPLAESPAS"
     misc_feature    329219..330187
                     /locus_tag="Smed_3872"
                     /note="The Ntn hydrolases (N-terminal nucleophile) are a
                     diverse superfamily of of enzymes that are activated
                     autocatalytically via an N-terminally lcated nucleophilic
                     amino acid.  N-terminal nucleophile (NTN-) hydrolase
                     superfamily, which contains a...; Region: Ntn_hydrolase;
                     cl00467"
                     /db_xref="CDD:241884"
     misc_feature    order(329507..329509,329555..329557,329561..329563,
                     329657..329659)
                     /locus_tag="Smed_3872"
                     /note="active site"
                     /db_xref="CDD:238884"
     misc_feature    329522..330139
                     /locus_tag="Smed_3872"
                     /note="Acyl-coenzyme A:6-aminopenicillanic acid
                     acyl-transferase; Region: AAT; pfam03417"
                     /db_xref="CDD:217546"
     gene            complement(330415..331377)
                     /locus_tag="Smed_3873"
                     /db_xref="GeneID:5318872"
     CDS             complement(330415..331377)
                     /locus_tag="Smed_3873"
                     /note="PFAM: dihydrodipicolinate synthetase;
                     KEGG: sme:SMb20259 putative dihydrodipicolinate synthase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthetase"
                     /protein_id="YP_001312618.1"
                     /db_xref="GI:150376022"
                     /db_xref="InterPro:IPR002220"
                     /db_xref="GeneID:5318872"
                     /translation="MKAKIFSGVIPALMTPCKEDRTPDFDALVRKGKALIADGMSAVV
                     YCGSMGDWPLLTDAQRMEGVERLTKAGIPVIVGTGAVNTAAAVAHAAHAQKVGAQGLM
                     VIPRVLSRGPSIVAQKAHFKAILTAAPDLPAVIYNSPYYGFATRADLFFALRAEHPNL
                     VGFKEFGGNADMRYAAENITSRDDGVSLMIGVDTAVFHGFVNCGATGAITGIGNVLPK
                     EVIHLCNLSQAAAAGDVDARQRAQELEQALAVLSSFDEGPDLVLYFKHMMVLKGDKEY
                     TLHFNETDALTESQRGYVEAQFRLFNTWYAEWCKLPGAVEKYRA"
     misc_feature    complement(330457..331374)
                     /locus_tag="Smed_3873"
                     /note="Dihydrodipicolinate synthase/N-acetylneuraminate
                     lyase [Amino acid transport and metabolism / Cell envelope
                     biogenesis, outer membrane]; Region: DapA; COG0329"
                     /db_xref="CDD:223406"
     misc_feature    complement(330562..331353)
                     /locus_tag="Smed_3873"
                     /note="Dihydrodipicolinate synthase family; Region:
                     DHDPS-like; cd00408"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(330886..330888,330970..330972,
                     331231..331239,331246..331248,331342..331344))
                     /locus_tag="Smed_3873"
                     /note="inhibitor site; inhibition site"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(330751..330753,330886..330888,
                     330970..330972,331231..331239,331246..331248))
                     /locus_tag="Smed_3873"
                     /note="active site"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(331018..331020,331030..331032,
                     331054..331059,331129..331134,331216..331221,
                     331234..331236))
                     /locus_tag="Smed_3873"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188630"
     misc_feature    complement(330886..330888)
                     /locus_tag="Smed_3873"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188630"
     gene            complement(331498..332208)
                     /locus_tag="Smed_3874"
                     /db_xref="GeneID:5318873"
     CDS             complement(331498..332208)
                     /locus_tag="Smed_3874"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20258 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312619.1"
                     /db_xref="GI:150376023"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318873"
                     /translation="MTDKDSDASSAPERKRGSGVKMVYDLLRDEILDLVLPPGSPIDE
                     VQLAERFKMSRTPIREALVRLAGEGLIATLPNRSTMVSNIDFLNLHTFFDALVLMYRV
                     TTRLAAEHHRQEDLEVIRARQAEFAAAVQAQDALAMIATNAAFHSAIAEAGRNPYFTG
                     LFNRLLDEGRRILRLYYQSYDDRLPQRFVDEHEDMIAVIAARDVEAADRLARTHAEQI
                     VEQIQKLFARKDRLEIAL"
     misc_feature    complement(331513..332184)
                     /locus_tag="Smed_3874"
                     /note="Transcriptional regulators [Transcription]; Region:
                     GntR; COG1802"
                     /db_xref="CDD:224715"
     misc_feature    complement(331963..332142)
                     /locus_tag="Smed_3874"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(331972..331983,331987..331992,
                     332020..332022,332029..332034,332038..332052,
                     332074..332079,332080..332082))
                     /locus_tag="Smed_3874"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(331567..331935)
                     /locus_tag="Smed_3874"
                     /note="FCD domain; Region: FCD; pfam07729"
                     /db_xref="CDD:219539"
     gene            complement(332366..333469)
                     /locus_tag="Smed_3875"
                     /db_xref="GeneID:5318555"
     CDS             complement(332366..333469)
                     /locus_tag="Smed_3875"
                     /note="PFAM: adenylyl cyclase class-3/4/guanylyl cyclase;
                     KEGG: sme:SMb20257 putative adenylate cyclase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenylate/guanylate cyclase"
                     /protein_id="YP_001312620.1"
                     /db_xref="GI:150376024"
                     /db_xref="InterPro:IPR001054"
                     /db_xref="GeneID:5318555"
                     /translation="MQGNRFALFQKLHYDRSMDLPAPLEWLLDEAGTSSGPDAFLAEL
                     GNRLLADGLPLAGGALTLAVRHPIIAQRTWLWRAENGAVIEALGFAEGPVDSAADWLA
                     GLGPVQEDIVGRSEKVIIGWAGMRPFDPAEVARLRQIARFAAAPLAVLGERATRAALL
                     EAYLGRRSAARVQAGALSRGTGESIRAALLYADLRNFTALSEENEPARVIAALNAWFD
                     RVAGAVHAFGGEVLKFIGDGVLAIFPVTGAPAEACEQALRAVVAARAGMAHLGSLRQE
                     QELPPLRFGAALHLGEILWGNVGSIDRLDFTAIGPAVNLVSRLEGLCRPLGRSVLISG
                     AIAAETETPLVSLGKHALRGIAAPCTVFTLPDA"
     misc_feature    complement(332372..333040)
                     /locus_tag="Smed_3875"
                     /note="Adenylate cyclase, family 3 (some proteins contain
                     HAMP domain) [Signal transduction mechanisms]; Region:
                     CyaA; COG2114"
                     /db_xref="CDD:225025"
     misc_feature    complement(332378..332914)
                     /locus_tag="Smed_3875"
                     /note="cyclase homology domain; Region: CHD; cd07302"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(332411..332413,332516..332521,
                     332528..332533,332543..332551,332750..332752,
                     332759..332767,332771..332773,332876..332893,
                     332897..332899))
                     /locus_tag="Smed_3875"
                     /note="nucleotidyl binding site; other site"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(332759..332761,332891..332893))
                     /locus_tag="Smed_3875"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(332411..332413,332528..332530,
                     332537..332548,332579..332581,332588..332590,
                     332768..332773,332807..332809,332819..332821,
                     332828..332833,332840..332842,332876..332878))
                     /locus_tag="Smed_3875"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143636"
     gene            333625..334074
                     /locus_tag="Smed_3876"
                     /db_xref="GeneID:5318556"
     CDS             333625..334074
                     /locus_tag="Smed_3876"
                     /note="PFAM: Activator of Hsp90 ATPase 1 family protein;
                     KEGG: sme:SMb20256 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="activator of Hsp90 ATPase 1 family protein"
                     /protein_id="YP_001312621.1"
                     /db_xref="GI:150376025"
                     /db_xref="InterPro:IPR013538"
                     /db_xref="GeneID:5318556"
                     /translation="MQETLVVRRETHVSAPPAAVFALLTDPEKILRWMGTEAEVEPKP
                     GGLYLVNVTGARFARGSFREVVPVHRLAYSFGWDGSDVVPPGSSLVEIDLVEEADGTL
                     VRLTHSGLPDAEQCAGHVEGWAHYLDRLSAAAAGRDPGPDPWHGRTG"
     misc_feature    333634..334014
                     /locus_tag="Smed_3876"
                     /note="Putative hydrophobic ligand-binding SRPBCC domain
                     of Micromonospora echinospora CalC, human Aha1, and
                     related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814"
                     /db_xref="CDD:176856"
     misc_feature    order(333637..333639,333643..333645,333649..333651,
                     333682..333690,333694..333699,333712..333714,
                     333736..333738,333760..333762,333766..333768,
                     333772..333774,333778..333780,333799..333804,
                     333808..333810,333817..333819,333835..333837,
                     333841..333846,333889..333894,333898..333900,
                     333904..333906,333934..333936,333940..333942,
                     333946..333948,333952..333954,333967..333993,
                     333997..334005,334012..334014)
                     /locus_tag="Smed_3876"
                     /note="putative hydrophobic ligand binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:176856"
     gene            334128..334730
                     /locus_tag="Smed_3877"
                     /db_xref="GeneID:5318557"
     CDS             334128..334730
                     /locus_tag="Smed_3877"
                     /note="PFAM: protein of unknown function DUF1003;
                     KEGG: sme:SMb20255 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312622.1"
                     /db_xref="GI:150376026"
                     /db_xref="InterPro:IPR010406"
                     /db_xref="GeneID:5318557"
                     /translation="MCLPVAVRARAAHKASRVMISTGKSAEQRSAARTMPRLERNISA
                     ILKRREEEERGRHAHDRLAQAITTFAGSMTFVCLHVLVFGAWIAANLGLVPNVPVFDP
                     TFAILAMIASVEAIFISTFVLISQNRMAEKDDERSDLNLQISLLAEQEATQLLTLLRE
                     IAGRLGVKVDGEEDIRELSKEVTPEEILNRLEDQKVRSGE"
     misc_feature    334215..334724
                     /locus_tag="Smed_3877"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG4420"
                     /db_xref="CDD:226844"
     gene            334831..335106
                     /locus_tag="Smed_3878"
                     /db_xref="GeneID:5318558"
     CDS             334831..335106
                     /locus_tag="Smed_3878"
                     /note="KEGG: sme:SMb20254 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312623.1"
                     /db_xref="GI:150376027"
                     /db_xref="GeneID:5318558"
                     /translation="MEESQAISRPQRPSDYSGRQMDCVAALRPAVSDLAATSQESIVA
                     AMSGELTDELLALAKRAERAGWTFDEASAAIQELAREYEGAKGTIFD"
     gene            335156..336220
                     /locus_tag="Smed_3879"
                     /db_xref="GeneID:5318559"
     CDS             335156..336220
                     /locus_tag="Smed_3879"
                     /note="KEGG: sme:SMb20253 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312624.1"
                     /db_xref="GI:150376028"
                     /db_xref="GeneID:5318559"
                     /translation="MAKLGVLTFHRCINYGSFWQTRCLVHGLRSLGTDPVILDHQSTR
                     VTRAEWRCAMQPLLPARTARPDIPLYASKIRKFQSALASLPTSASFALDDPAGAEECD
                     ILVVGSDEVWNFRHPWYGGCSLFYGEGLAAKKKVSYAATFGNHPAANGLEPYWAERLR
                     NFDGISVRDENSRAIIEKEVGREAILVLDPCLQFPETISFGPNASASRPYMAVYGHSF
                     PSWFQNAVRLWAGARSLPLVSVGYRNEWADEQWLDAGPYEFAAWMAGAEAVATNFFHG
                     CVFSLLNSKPFVTALSDYRSNKIADLARTAGAERHVMSQETRPAEYEAVLAEGLDPAI
                     IHRLAELRRQSRIYLTDVLA"
     misc_feature    335195..336019
                     /locus_tag="Smed_3879"
                     /note="Polysaccharide pyruvyl transferase; Region:
                     PS_pyruv_trans; pfam04230"
                     /db_xref="CDD:217977"
     gene            336267..337646
                     /locus_tag="Smed_3880"
                     /db_xref="GeneID:5318560"
     CDS             336267..337646
                     /locus_tag="Smed_3880"
                     /note="KEGG: sme:SMb20252 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312625.1"
                     /db_xref="GI:150376029"
                     /db_xref="GeneID:5318560"
                     /translation="MVKSGLCIGCGTCMAESGDGAAMHLDRYGQLKPDRSNNPAGFAE
                     LCPFSPHARSEDQIALARFGSARFYDSRIGRFEAAYVGHVLEGSFRVDGSSGGMASWT
                     AAELLRRKLVDAVAHVVPREGDGERLFRYQLSRTAEDLRKGAKSRYHPVELSGVVAEM
                     KRHPGRYAVVGIPCFIKALHLLSLQDPALRERLAFTLGLFCGHMKSTRFVESFAWQMG
                     TDMNAVAGVDYRLKDPRRPANWYTAHLRLKDGSTRSKDWWHLVDGDWGAGFFQNSACN
                     FCDDVVAETADISFGDAWVEPYSSDGLGTNVVIVRSPLLQALVADAVKEGRLELREVD
                     SDFIVETQAAGFRQRREGLAFRLAWPRSGVQPRKRVAPAWKGLPAQRMLVYGLRSAIS
                     AASHRVFWFARTMKIPAAYIHWASAMLALYQGVTYSRGWIGKLVDGVSMRGRKRSKDE
                     GSKDEGAGA"
     misc_feature    336267..337415
                     /locus_tag="Smed_3880"
                     /note="Coenzyme F420-reducing hydrogenase, beta subunit
                     [Energy production and conversion]; Region: FrhB; COG1035"
                     /db_xref="CDD:223966"
     misc_feature    336495..336743
                     /locus_tag="Smed_3880"
                     /note="Coenzyme F420 hydrogenase/dehydrogenase, beta
                     subunit N-term; Region: FrhB_FdhB_N; pfam04422"
                     /db_xref="CDD:218081"
     misc_feature    336762..337271
                     /locus_tag="Smed_3880"
                     /note="Coenzyme F420 hydrogenase/dehydrogenase, beta
                     subunit C terminus; Region: FrhB_FdhB_C; pfam04432"
                     /db_xref="CDD:218086"
     gene            complement(337544..338521)
                     /locus_tag="Smed_3881"
                     /db_xref="GeneID:5318561"
     CDS             complement(337544..338521)
                     /locus_tag="Smed_3881"
                     /note="KEGG: sme:SMb20251 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312626.1"
                     /db_xref="GI:150376030"
                     /db_xref="GeneID:5318561"
                     /translation="MIEAAMIWNEPNNKSHWDPEIDPDWSRFAHMAKLAANAIREVNP
                     GLTRVLGGISPIDPNFLALMKSQGVLDHLDAVAAHGFPLDWNLWQIHEWPQKLEELRS
                     VTELPVWVSEVGVSTFGAEEVQLWGLKKTAELLKGRAERIQWYSLYDLPRAWPATTRH
                     REAEGSSYYRHFYMGLLREDGSPKLALDEFARHTPDIGLVQWFHFEDPRLDDAVAWMK
                     RLGVTYLRTGLSWADRFRPNALDWFDRQMEALEDFDVTVTFCFTPEHRGLAPHHTSAP
                     LVPDEFAEFCAEMTARYAPAPSSFEPSSFERLRPRIETPSTSLPIQPRE"
     misc_feature    complement(337547..338521)
                     /locus_tag="Smed_3881"
                     /note="Beta-xylosidase [Carbohydrate transport and
                     metabolism]; Region: XynB; COG3664"
                     /db_xref="CDD:226190"
     gene            complement(338563..339159)
                     /locus_tag="Smed_3882"
                     /db_xref="GeneID:5318562"
     CDS             complement(338563..339159)
                     /locus_tag="Smed_3882"
                     /note="PFAM: Phosphoglycerate mutase;
                     KEGG: sme:SMb20250 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="YP_001312627.1"
                     /db_xref="GI:150376031"
                     /db_xref="InterPro:IPR013078"
                     /db_xref="GeneID:5318562"
                     /translation="MTTTFLLVRHAAHDNVGCYLAGRTGDVPLGAAGREQAQRLSARL
                     SGQGIRAIYASPRKRTQQTAEAIAAVSDVSEVLTTEALDEVDFGEWSGKTFDVLDEDP
                     HWRRWNAVRSLVRAPGGETMLDVQSRAVGLVAALAQRHGQEKIVLVSHADVIKTVVCH
                     VLGLSADAWPRFDIAPASISVVAMGDWGAKILTLNEYV"
     misc_feature    complement(338575..339150)
                     /locus_tag="Smed_3882"
                     /note="Histidine phosphatase domain found in
                     phosphoglycerate mutases and related proteins, mostly
                     phosphatases; contains a His residue which is
                     phosphorylated during the reaction; Region: HP_PGM_like;
                     cd07067"
                     /db_xref="CDD:132718"
     misc_feature    complement(order(338707..338712,338983..338985,
                     339130..339135))
                     /locus_tag="Smed_3882"
                     /note="catalytic core [active]"
                     /db_xref="CDD:132718"
     gene            complement(339156..340259)
                     /locus_tag="Smed_3883"
                     /db_xref="GeneID:5318563"
     CDS             complement(339156..340259)
                     /locus_tag="Smed_3883"
                     /note="PFAM: Myo-inositol-1-phosphate synthase;
                     Myo-inositol-1-phosphate synthase GAPDH domain protein;
                     KEGG: sme:SMb20249 myo-inositol-1-phosphate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inositol-1-phosphate synthase"
                     /protein_id="YP_001312628.1"
                     /db_xref="GI:150376032"
                     /db_xref="InterPro:IPR002587"
                     /db_xref="InterPro:IPR013021"
                     /db_xref="GeneID:5318563"
                     /translation="MGSKSIRVGLVGIGNCASSLVQGLTFYRDAKEDEPVPGLMHANL
                     GGYHVGDIEISAAFDVAASKVGRDVAEAIYAAPNNTFRFANAPSTGVVVQRGRTLDGI
                     GRYLREEIEESDVPAADVADVLRQTETDVLVSYLPVGSEVATRWYAEQALAAGCGFVN
                     CIPVFIASDKSWQRKFAERGLPLIGDDIKSQVGATIVHRLLANLFRDRGVRIDRTYQL
                     NFGGNTDFLNMLERERLESKKISKTQSVVSQMDIPLAAGDIHVGPSDHVPWLADRKFA
                     YIRVEGTTFGNVPLNVELKLEVWDSPNSAGVVIDAVRCAKLAIDRGIAGPLIAPSSYF
                     MKSPPQQFTDAEARRRLEEFIAGETGALLGAAE"
     misc_feature    complement(339195..340259)
                     /locus_tag="Smed_3883"
                     /note="Myo-inositol-1-phosphate synthase [Lipid
                     metabolism]; Region: INO1; COG1260"
                     /db_xref="CDD:224180"
     misc_feature    complement(339195..340244)
                     /locus_tag="Smed_3883"
                     /note="Myo-inositol-1-phosphate synthase; Region:
                     NAD_binding_5; cl00554"
                     /db_xref="CDD:241944"
     gene            340409..342157
                     /locus_tag="Smed_3884"
                     /db_xref="GeneID:5318564"
     CDS             340409..342157
                     /locus_tag="Smed_3884"
                     /note="KEGG: sme:SMb20248 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312629.1"
                     /db_xref="GI:150376033"
                     /db_xref="GeneID:5318564"
                     /translation="MLVYGDAKRLERADELSASIASRLRRIEDQPPGIERHTELVAIL
                     LKAGELVQGLSDAEFKQARADEISASREAGERLLLDLAMLVARSWQRGFTERVSVPAH
                     VANLLATISAPISLGIREPEGYAFYALYPESYLEAARESGLGSDAVVIGLRSIGTTLS
                     AIVAAALHAAPPLTLRPKGDPFRRQLAIAPQLAGRLLRNPAAGFAIVDEGPGLSGSSF
                     GCVADWLEDHGVAATRIHFFPSHKGDLGPQSCGRHRRRWATSPRHVVDVDDLLIKPAG
                     SPRHLAEWVGRLVGPLERPLEDISAGGWRKALPGDCRPPVDIRFERKKFLARTADGAW
                     LVKFAGLADVGQRKLVRARLLADAGFAPPVAGLCHGFLVQKWVAARPMAPSELRHPAF
                     IAHLGRYLAFRARSLPPPKTQGASIAQLCEIASVNTEEGLGSAAASRLKSRLRNAERF
                     HAAILPVDTDNRLHSWEWLGEGARQFLKADALDHSGGHDLVGSQDIGWDIAGARIELG
                     LTRDEQAELRAAVSENGWRPPDAELQEIFDLCYAAFQFGLWASAKSAAAPEEVHRLET
                     AAARYGSLLRNATEGF"
     gene            complement(342261..343286)
                     /locus_tag="Smed_3885"
                     /db_xref="GeneID:5318679"
     CDS             complement(342261..343286)
                     /locus_tag="Smed_3885"
                     /note="PFAM: oxidoreductase domain protein; Oxidoreductase
                     domain;
                     KEGG: sme:SMb20247 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain-containing protein"
                     /protein_id="YP_001312630.1"
                     /db_xref="GI:150376034"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="GeneID:5318679"
                     /translation="MSDAMQLSTKPKMATRPRVGFLGVGRIGFHRMKAVVETGSVETV
                     AIFDPSPEMAAAARELTPEASIVNSLEALLDQALDGIVIASPSALHAAQSIVALEQGV
                     AVFCQKPLGRTRDETAAVVETARHVDRLLNVDLSYRYTEGMRQIRDLIASGELGTVFA
                     VDLTFHNAYGPSKPWFYDKALSGGGCVIDLGVHLVDLLLWVLGFPDVVGVQSRLFAKG
                     LPIRRDGDEVEDYAIATLELANGVVARMACSWHLQAGCDAVISADFYGTEGGASLRNI
                     NGSYLDFSAERYRSTQREVLALPPDNWGGRAAAAWAERLAAGERFDPENDYLVAVADV
                     LDRIYDR"
     misc_feature    complement(<342435..343235)
                     /locus_tag="Smed_3885"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:223745"
     misc_feature    complement(342885..343235)
                     /locus_tag="Smed_3885"
                     /note="Oxidoreductase family, NAD-binding Rossmann fold;
                     Region: GFO_IDH_MocA; pfam01408"
                     /db_xref="CDD:201778"
     misc_feature    complement(342537..342848)
                     /locus_tag="Smed_3885"
                     /note="Oxidoreductase family, C-terminal alpha/beta
                     domain; Region: GFO_IDH_MocA_C; pfam02894"
                     /db_xref="CDD:217272"
     gene            complement(343279..344271)
                     /locus_tag="Smed_3886"
                     /db_xref="GeneID:5318680"
     CDS             complement(343279..344271)
                     /locus_tag="Smed_3886"
                     /note="PFAM: Alcohol dehydrogenase zinc-binding domain
                     protein; Alcohol dehydrogenase GroES domain protein;
                     KEGG: sme:SMb20246 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="YP_001312631.1"
                     /db_xref="GI:150376035"
                     /db_xref="InterPro:IPR002328"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="GeneID:5318680"
                     /translation="MNIRMSQRTDTMSAAIVTGPGTVRIERLPLPQPGRGQVRIRLEG
                     CGVCASNLVPWAGPEWMRFPTEPGALGHEGWGVIDAVGEGVHGFSPGDRVAALSYNAY
                     ATHDIADQSAIARLPASLADQPFPGEPLGCAFNILRRSAITPGETVAIIGIGFLGVLL
                     TELVSAAGARVIAISRRPSSLAAAKQAGASDVIPMDDHWRIIEEVKQLTDGRFCDCVI
                     EAVGKQWPLDLAGELTRERGRLVIAGYHQDSPRQVNMQLWNWRGLDVINAHERDPAVY
                     MRGMREAIEATAAGRISPARLYTHRFPLEELGAALDMTRDRPEGFIKALVICHE"
     misc_feature    complement(343294..344241)
                     /locus_tag="Smed_3886"
                     /note="Threonine dehydrogenase and related Zn-dependent
                     dehydrogenases [Amino acid transport and metabolism /
                     General function prediction only]; Region: Tdh; COG1063"
                     /db_xref="CDD:223991"
     misc_feature    complement(343291..344223)
                     /locus_tag="Smed_3886"
                     /note="Alcohol dehydrogenases of the MDR family; Region:
                     Zn_ADH9; cd08269"
                     /db_xref="CDD:176230"
     misc_feature    complement(order(343462..343470,343540..343545,
                     343603..343605,343609..343614,343651..343653,
                     343732..343734,343744..343749,343801..343818,
                     343876..343878,343888..343890,344113..344115,
                     344122..344130))
                     /locus_tag="Smed_3886"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176230"
     misc_feature    complement(order(343888..343890,344053..344058,
                     344128..344130))
                     /locus_tag="Smed_3886"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176230"
     gene            344603..345709
                     /locus_tag="Smed_3887"
                     /db_xref="GeneID:5318681"
     CDS             344603..345709
                     /locus_tag="Smed_3887"
                     /note="PFAM: NAD-dependent epimerase/dehydratase;
                     short-chain dehydrogenase/reductase SDR; 3-beta
                     hydroxysteroid dehydrogenase/isomerase; polysaccharide
                     biosynthesis protein CapD; dTDP-4-dehydrorhamnose
                     reductase; Male sterility domain; KR domain protein;
                     KEGG: sme:SMb20245 putative NDP-glucose
                     dehydrataseepimerase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="YP_001312632.1"
                     /db_xref="GI:150376036"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR008089"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5318681"
                     /translation="MTKVLVTGGCGFIGRHVVEELLSGNYELRILDALNEQVHADAQI
                     TLPPEVDMRRADICDADAVKSALKDVDHVIHLAAEVGVGQSMYEISRYVGVNDLGTAV
                     LLEAMIGMPIRRIVVASSMSVYGEGLYETAAGERRAHIRRSPAEIKTGAWNPSGPDGE
                     SLKPIATDENKPVDLASIYALTKYAQERQVLIFGEAYGMDAVALRLFNVYGAGQALSN
                     PYTGVLANFASRLANGQAPMVFEDGRQKRDFVHVRDVARAFRLALEQPHAAGHVINIG
                     SGHAYAIADIASLLADAMGVPEIGPEIMHKARSGDIRNCFADISKARDLLGFEPAHRL
                     EDSLADFAQWVRSAGAIDRGAEMKRHLEARGLVL"
     misc_feature    344609..345655
                     /locus_tag="Smed_3887"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    344609..345634
                     /locus_tag="Smed_3887"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    order(344624..344626,344630..344635,344639..344641,
                     344696..344704,344828..344836,344954..344962,
                     345137..345139,345149..345151,345218..345229)
                     /locus_tag="Smed_3887"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    order(344888..344890,344960..344962,345137..345139,
                     345149..345151)
                     /locus_tag="Smed_3887"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            345706..346827
                     /locus_tag="Smed_3888"
                     /db_xref="GeneID:5318682"
     CDS             345706..346827
                     /locus_tag="Smed_3888"
                     /note="PFAM: NAD-dependent epimerase/dehydratase;
                     short-chain dehydrogenase/reductase SDR; 3-beta
                     hydroxysteroid dehydrogenase/isomerase; polysaccharide
                     biosynthesis protein CapD; dTDP-4-dehydrorhamnose
                     reductase; Male sterility domain;
                     KEGG: sme:SMb20244 putative CDP-tyvelose-2-epimerase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="YP_001312633.1"
                     /db_xref="GI:150376037"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318682"
                     /translation="MSGRTVEKSRHLATPALSGKAGPILVVGGSGFVGSNLADSFLRD
                     GEHVIVLDNLSRPGVERNLEWLVESHGRAVEAVTADIRDLAAIQPAFRNAKAVFHFAA
                     QTAVTTSLQQPTEDFETNARGTLNVLEAARLAGRSSPVIFASTNKVYGALEHMEMRDV
                     QGRYMPVDEATRAHGVGEAQPLDFCTPYGCSKGVADQYVLDYARSFGLPTAVLRMSCV
                     YGPRQFGTEDQGWVAHFLIRALAGEPISIYGDGKQVRDILHVTDAVAAYRAVLKAIDG
                     LKGRAFNLGGGPDNAVSIVEVLNEIEILTGRRLSTGKSDWRAGDQLYFVADTRAIADA
                     VGWRAGMAWREGLRNLYAWLVEDRVGVGNIRRQQRRVPA"
     misc_feature    345772..346767
                     /locus_tag="Smed_3888"
                     /note="CDP-tyvelose 2-epimerase, extended (e) SDRs;
                     Region: CDP_TE_SDR_e; cd05258"
                     /db_xref="CDD:187568"
     misc_feature    345775..346767
                     /locus_tag="Smed_3888"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    order(345787..345789,345793..345804,345859..345873,
                     345940..345948,346003..346011,346015..346017,
                     346060..346062,346132..346137,346267..346269,
                     346279..346281,346348..346359,346390..346392)
                     /locus_tag="Smed_3888"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187568"
     misc_feature    order(345862..345870,345883..345885,345937..345939,
                     345943..345945,345949..345963,345970..345972,
                     346033..346035,346039..346050,346054..346059,
                     346066..346068,346090..346092,346099..346101,
                     346240..346257,346261..346266,346273..346278,
                     346285..346287,346294..346299,346306..346311,
                     346315..346317,346321..346323,346657..346659)
                     /locus_tag="Smed_3888"
                     /note="homotetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187568"
     misc_feature    order(345955..345957,346033..346035,346042..346044,
                     346054..346056,346066..346068,346090..346092,
                     346099..346101,346240..346257,346261..346266,
                     346273..346278,346285..346287,346294..346299,
                     346306..346311,346315..346317,346321..346323,
                     346657..346659)
                     /locus_tag="Smed_3888"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187568"
     misc_feature    order(346063..346065,346138..346140,346267..346269,
                     346279..346281)
                     /locus_tag="Smed_3888"
                     /note="active site"
                     /db_xref="CDD:187568"
     misc_feature    order(346144..346146,346354..346356,346384..346386,
                     346393..346398,346405..346410,346444..346449,
                     346462..346464,346468..346470,346585..346587,
                     346654..346656,346663..346665)
                     /locus_tag="Smed_3888"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187568"
     gene            346824..347975
                     /locus_tag="Smed_3889"
                     /db_xref="GeneID:5318683"
     CDS             346824..347975
                     /locus_tag="Smed_3889"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb20243 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001312634.1"
                     /db_xref="GI:150376038"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318683"
                     /translation="MSVHALSGSRQEVRHDAPSPLPRRILMTVDAVGGVWRYAVDLAE
                     AMRRSGVETLIVGFGPAPSPEQRREAESIGRLEWSDQPLDWMVEDESELCGVPDLLSE
                     LALKHSVDLMHLNLPSQASGITAEIPVVTVSHSCVATWFEAVRGSGLPTGWCWQKRLN
                     RIGFDRADLVLAPSRSHAMAVTRCYGPVRDLAVVYNASRNASSISAKENFAFAAGRWW
                     DEGKNGAVLDRAAADIGWPVVMAGACDGPNGQRLAIAHADHKGELSHDRAISLMSRAA
                     IVVSPSVYEPFGLVALEAARAGAALVLADIETYRELWEGSALFADAEDPAAFAGAVNR
                     LAEDAGFRAELGRRAQSRGSDFTLEAQREAIFAAYRRVMRGENRRTAAE"
     misc_feature    346893..347933
                     /locus_tag="Smed_3889"
                     /note="Glycosyltransferases catalyze the transfer of sugar
                     moieties from activated donor molecules to specific
                     acceptor molecules, forming glycosidic bonds. The acceptor
                     molecule can be a lipid, a protein, a heterocyclic
                     compound, or another carbohydrate...; Region:
                     Glycosyltransferase_GTB_type; cl10013"
                     /db_xref="CDD:245227"
     misc_feature    346917..347951
                     /locus_tag="Smed_3889"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     gene            347980..349110
                     /locus_tag="Smed_3890"
                     /db_xref="GeneID:5318684"
     CDS             347980..349110
                     /locus_tag="Smed_3890"
                     /note="KEGG: sme:SMb20242 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312635.1"
                     /db_xref="GI:150376039"
                     /db_xref="GeneID:5318684"
                     /translation="MRFLFYTHSLISDWNHGNAHFLRGVMREITRRGHLAVALEPGDS
                     WSRRNLIADQGIGPIAAFRKHFPDLQVAIYESDFDHEAAVAEADIVIVHEWTDPALIA
                     ELGRIRLKGGRFTLAFHDTHHRAVSAKRDIARLDLSGYDFVLAFGEALRERYLQAGWG
                     RHVHTWHEAADTSLFHPMPEVEKRGELIWIGNWGDDERSSEIMSFLVEPAKKLKLRAT
                     VRGVRYPDTALRALRAAEIDYGGWLANAAVPRAFAEHRVTMHIPRRPYVEALPGIPTI
                     RVFEALSCGIPLVSAPWTDAEGLFRPGKDFCIARDGKEMARLLRQLLAEPAFATEMAA
                     SGLETVRARHTCGHRVDELLSILAAYMPHSNVERTVTEEVQL"
     misc_feature    347986..349065
                     /locus_tag="Smed_3890"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4641"
                     /db_xref="CDD:226988"
     misc_feature    348790..349044
                     /locus_tag="Smed_3890"
                     /note="Glycosyl transferases group 1; Region:
                     Glyco_trans_1_2; pfam13524"
                     /db_xref="CDD:222197"
     gene            349107..350192
                     /locus_tag="Smed_3891"
                     /db_xref="GeneID:5318685"
     CDS             349107..350192
                     /locus_tag="Smed_3891"
                     /note="KEGG: sme:SMb20241 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312636.1"
                     /db_xref="GI:150376040"
                     /db_xref="GeneID:5318685"
                     /translation="MKLAFYGSSLVSAYWNGAATYYRGLLRALAQRGYQITFYEPDVY
                     DRQMHRDIDPPFWCKVVVYEGTIEGLKSVAGKAGEADIVVKASGVGFEDELLLAEVMA
                     AADPAALKIFWDVDAPATLADLRAAPDHPLRRALPSLDLVLTYGGGDPVVGAYRALGA
                     RECVPIYNAVDPETHYPVSPDPRFNADLAFLGNRLPDREERVEAFFLEPAQKLWQRRF
                     LLGGAGWHDKSLSPNVAYIGHVPTADHNAFNTTPTAVLNISRSSMADNGFSPATRVFE
                     AAGAGACLITDYWEGIELFLKPGEEVLVARDGRDVAELMQKLTSANAREIGERALRRV
                     LAEHTYAHRAAEVDRILRQARRMEAAE"
     misc_feature    349113..350189
                     /locus_tag="Smed_3891"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4641"
                     /db_xref="CDD:226988"
     misc_feature    349869..350147
                     /locus_tag="Smed_3891"
                     /note="Glycosyl transferases group 1; Region:
                     Glyco_trans_1_2; pfam13524"
                     /db_xref="CDD:222197"
     gene            350189..351307
                     /locus_tag="Smed_3892"
                     /db_xref="GeneID:5318686"
     CDS             350189..351307
                     /locus_tag="Smed_3892"
                     /note="KEGG: sme:SMb20240 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312637.1"
                     /db_xref="GI:150376041"
                     /db_xref="GeneID:5318686"
                     /translation="MKRPLDIVILGLSLSSSWGNGHATTYRALLRAVNAAGHKVTFLE
                     RDVPWYADNRDLAVPDFCDLVLYDDTDELTQRHARKLADADAVVVGSYVPDGVDVIDA
                     VADLVPKRLCFYDIDTPVTLAKLERGDEEYLARRQVAFFDIYFSFSGGKTLDRLRDEF
                     AARRPVPLYCAVDLEAYRNTGAPTKWDLGYLGTFSPDRQPVLERLLIEPARRLPHMRF
                     AVAGPSYPSDIHWPPNVERIEHLPPGEHAEFYSRQRFTLNVTRADMVAAGWSPSVRLF
                     EAAACRTPIVSDWWEGIENFFPPGEAVVIAQSSSDVVTALTSPDEAQREALADCAYRR
                     VAAEHSSAARARSFVEALESVAARTDLATQRVERRLPV"
     sig_peptide     350189..350260
                     /locus_tag="Smed_3892"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.837) with cleavage site probability 0.805 at
                     residue 24"
     misc_feature    350252..351295
                     /locus_tag="Smed_3892"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4641"
                     /db_xref="CDD:226988"
     misc_feature    350951..>351184
                     /locus_tag="Smed_3892"
                     /note="Glycosyl transferases group 1; Region:
                     Glyco_trans_1_2; pfam13524"
                     /db_xref="CDD:222197"
     gene            351327..352367
                     /locus_tag="Smed_3893"
                     /db_xref="GeneID:5318687"
     CDS             351327..352367
                     /locus_tag="Smed_3893"
                     /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase;
                     dTDP-4-dehydrorhamnose reductase;
                     KEGG: sme:SMb20239 putative dTDP-glucose 4,6-dehydratase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="YP_001312638.1"
                     /db_xref="GI:150376042"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="GeneID:5318687"
                     /translation="MAKRNKASRGKIILVAGGAGFVGSHLCSALLGAGNRVICLDSYL
                     TGSPANLTGLQNDPYFAMVEQDVCDEIDIDEPVDQIYNLACPASPPAYQADPIHTMMT
                     SVTGTGNLLRLAERHGATLLQASTSEIYGDPEEHPQQENYWGHVNCTGPRACYDEGKR
                     AAEALCFDSLRGGSVDARVARIFNTYGPHMRPNDGRIVSNFIVQALKNEPLTVYGSGE
                     QTRSFCYVSDLVDGLIRLMNREENPAVPVNLGNPGEFTVIELAELVLSRIETTSTIVH
                     EPLPADDPQRRRPDIARARKLLGWEPKVPLEEGLTHTIAWFQSALGSSRPERRTGRTR
                     RQPQLAAVTQDL"
     sig_peptide     351327..351416
                     /locus_tag="Smed_3893"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.985) with cleavage site probability 0.565 at
                     residue 30"
     misc_feature    351357..352280
                     /locus_tag="Smed_3893"
                     /note="UDP-glucuronate decarboxylase (UGD) and related
                     proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230"
                     /db_xref="CDD:187541"
     misc_feature    351357..352277
                     /locus_tag="Smed_3893"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    order(351375..351377,351381..351392,351447..351464,
                     351519..351527,351573..351587,351630..351632,
                     351696..351704,351789..351791,351801..351803,
                     351870..351881,351912..351914)
                     /locus_tag="Smed_3893"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187541"
     misc_feature    order(351534..351539,351648..351653,351660..351665,
                     351669..351674,351831..351833)
                     /locus_tag="Smed_3893"
                     /note="putative substrate binding site 2 [chemical
                     binding]; other site"
                     /db_xref="CDD:187541"
     misc_feature    order(351591..351593,351780..351782,351876..351878,
                     351909..351917,351924..351929,351960..351968,
                     351981..351983,351987..351989,352095..352097,
                     352173..352175,352185..352187)
                     /locus_tag="Smed_3893"
                     /note="putative substrate binding site 1 [chemical
                     binding]; other site"
                     /db_xref="CDD:187541"
     misc_feature    order(351633..351635,351702..351704,351789..351791,
                     351801..351803)
                     /locus_tag="Smed_3893"
                     /note="active site"
                     /db_xref="CDD:187541"
     gene            352370..353143
                     /locus_tag="Smed_3894"
                     /db_xref="GeneID:5318688"
     CDS             352370..353143
                     /locus_tag="Smed_3894"
                     /note="PFAM: Methyltransferase type 11; Methyltransferase
                     type 12;
                     KEGG: sme:SMb20238 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="type 11 methyltransferase"
                     /protein_id="YP_001312639.1"
                     /db_xref="GI:150376043"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="GeneID:5318688"
                     /translation="MVQQMRDRTNIAHEIAALGPWFHNMRIGGIETAPDHFLGDYPAV
                     KWKAFRHVVPEDLEGRSVLDIGCNAGFYAQEMKRRNAGRVLGIDSDPHYLRQAKFAAE
                     QAGVEIEFRLMSVYDAARLREKFDLVIFMGVLYHLRHPLLALDLLYEHVVGDQMLFQC
                     MQRGSDAVASLEGDYEFGEWGIFDRPDYPKLFFVEHRFADDPTNWFIPNRAGVEAMLR
                     SAGFVIEANPEREVYLLRRGKRPYLDEPTLSVLGGPAGL"
     misc_feature    352508..353044
                     /locus_tag="Smed_3894"
                     /note="Methyltransferase domain; Region: Methyltransf_23;
                     pfam13489"
                     /db_xref="CDD:222171"
     misc_feature    352553..>352759
                     /locus_tag="Smed_3894"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(352562..352582,352631..352636,352706..352714)
                     /locus_tag="Smed_3894"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(353176..353472)
                     /locus_tag="Smed_3895"
                     /pseudo
                     /db_xref="GeneID:5318208"
     gene            353503..353969
                     /locus_tag="Smed_3896"
                     /pseudo
                     /db_xref="GeneID:5318209"
     gene            complement(354012..354263)
                     /locus_tag="Smed_3897"
                     /db_xref="GeneID:5318210"
     CDS             complement(354012..354263)
                     /locus_tag="Smed_3897"
                     /note="KEGG: mes:Meso_2789 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312640.1"
                     /db_xref="GI:150376044"
                     /db_xref="GeneID:5318210"
                     /translation="MNACSAADRVLELANRRSLQMPERRRPPKDPLSELAAREEALYL
                     RRSSTRFLECAIHLCVTHMTLQEVADLLEKEAAQLRRFG"
     gene            complement(354260..354604)
                     /locus_tag="Smed_3898"
                     /db_xref="GeneID:5318211"
     CDS             complement(354260..354604)
                     /locus_tag="Smed_3898"
                     /note="KEGG: sme:SMb20236 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312641.1"
                     /db_xref="GI:150376045"
                     /db_xref="GeneID:5318211"
                     /translation="MANPASNPAQVRGDIQHGRTGDKRRGFDPAAAPLETDAEAAGTP
                     PGEDAIRTARVGQAEGRPADTATEYNDAMRPLSAAETAEANKQRLGMSLAIIGGAILL
                     GALIYAGGLFSP"
     gene            complement(354820..355785)
                     /locus_tag="Smed_3899"
                     /db_xref="GeneID:5318212"
     CDS             complement(354820..355785)
                     /locus_tag="Smed_3899"
                     /note="KEGG: sme:SMb20229 probable nutrient
                     deprivation-induced protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nutrient deprivation-induced protein"
                     /protein_id="YP_001312642.1"
                     /db_xref="GI:150376046"
                     /db_xref="GeneID:5318212"
                     /translation="MNDSAHTHSAAELQREIEADRQRIEEKLHEIQERMSPGELMDEL
                     LEYAKTSGGSEYLSNLGVALKSNPIPVALMGVSLAWLIANPASRAPRHEEQDDDYPLA
                     PVRGSVRRVGPVESSFGERYSHFTDESGSRFRALTDDAGRRAGHFIDPAGKVYRGFAD
                     AAGKQIEDIRDETGALFDEASGWASRTWRQVSAAAGRMSASVTGAGRSFADSMQGAGR
                     SLEEQGAQLNAAILRHFRDQPLVGGALAFAAGAAIGAALPHSEAEDAAMGGMAEDMRS
                     NISARANAGVAQAMEAGQEILDKAGEAVLEAHDAAKDRLQRPVQE"
     misc_feature    complement(355624..355767)
                     /locus_tag="Smed_3899"
                     /note="Protein of unknown function (DUF3618); Region:
                     DUF3618; pfam12277"
                     /db_xref="CDD:204869"
     gene            complement(355782..356201)
                     /locus_tag="Smed_3900"
                     /db_xref="GeneID:5318213"
     CDS             complement(355782..356201)
                     /locus_tag="Smed_3900"
                     /note="KEGG: sme:SMb20228 putative nutrient
                     deprivation-induced protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nutrient deprivation-induced protein"
                     /protein_id="YP_001312643.1"
                     /db_xref="GI:150376047"
                     /db_xref="GeneID:5318213"
                     /translation="MANHRDERPLSELMTGLVADISGLFRKEIDLAKAEASENLNRAV
                     GSFETLLVGLIFAIGAVGVLLSAVVQGLGAFLVAQGMSEANADALSAAIVGVVVALLA
                     WIMISRGLSALKGGSIKFDRTAASLQRDANVVKERLQ"
     misc_feature    complement(355791..356174)
                     /locus_tag="Smed_3900"
                     /note="Protein of unknown function (DUF1469); Region:
                     DUF1469; pfam07332"
                     /db_xref="CDD:219376"
     gene            complement(356194..356766)
                     /locus_tag="Smed_3901"
                     /db_xref="GeneID:5318214"
     CDS             complement(356194..356766)
                     /locus_tag="Smed_3901"
                     /note="KEGG: sme:SMb20227 probable nutrient
                     deprivation-induced protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nutrient deprivation-induced protein"
                     /protein_id="YP_001312644.1"
                     /db_xref="GI:150376048"
                     /db_xref="GeneID:5318214"
                     /translation="MTNDTTGRGSGDPLGRPLTAAQGIERVSGVQTGDIGRDSADRNL
                     QNAVREDVNEFKQFAGEQTEQAKAAISRAVEDEKNVAARQLEGVAAALEKVGSELEQS
                     DQRAIGRYAKQIGTSLHSFARKAEGRNLGEIAGMVEDFGRKQPLAFLGMAAIAGLAAS
                     RFLTASPPRRNGQDASGGNRQTSEKEPYNG"
     gene            complement(356886..357059)
                     /locus_tag="Smed_3902"
                     /db_xref="GeneID:5318215"
     CDS             complement(356886..357059)
                     /locus_tag="Smed_3902"
                     /note="KEGG: sme:SMb20226 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312645.1"
                     /db_xref="GI:150376049"
                     /db_xref="GeneID:5318215"
                     /translation="MLTNYFWLFVTGGGAFILGAAVAYAILRQRPLSRAERQAQKRKV
                     EELYEQSPENRTR"
     sig_peptide     complement(356982..357059)
                     /locus_tag="Smed_3902"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.962) with cleavage site probability 0.523 at
                     residue 26"
     gene            357222..357917
                     /locus_tag="Smed_3903"
                     /db_xref="GeneID:5318216"
     CDS             357222..357917
                     /locus_tag="Smed_3903"
                     /note="PFAM: transport-associated;
                     SMART: Transport-associated and nodulation region;
                     KEGG: sme:SMb20225 probable osmotically inducible sensory
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transport-associated protein"
                     /protein_id="YP_001312646.1"
                     /db_xref="GI:150376050"
                     /db_xref="InterPro:IPR007055"
                     /db_xref="InterPro:IPR014004"
                     /db_xref="GeneID:5318216"
                     /translation="MAGKKSWSRDVYEHYPESDRRWRARSYEDERRRDPAEGSRLVGD
                     ENSEYFPGAEPGRAGAFRGTGKTHSRWNGERDYGPDTFGGGGYHGDDDYGHRYRHGGR
                     GIEGRGFLERASDEVSSWFGDEDAERRRMQDQHRGKGPKGYTRSDTRIQEDVSDRLSD
                     EGMLDASGIAVSVANGEVQLSGLVDSKWAKRRAENCADAVSGVKHVQNNLRVRPSGGA
                     PGWNAGNTDRNIA"
     misc_feature    <357531..357863
                     /locus_tag="Smed_3903"
                     /note="Predicted periplasmic or secreted lipoprotein
                     [General function prediction only]; Region: OsmY; COG2823"
                     /db_xref="CDD:225379"
     misc_feature    357711..357863
                     /locus_tag="Smed_3903"
                     /note="BON domain; Region: BON; pfam04972"
                     /db_xref="CDD:203137"
     gene            complement(357970..358473)
                     /locus_tag="Smed_3904"
                     /db_xref="GeneID:5318217"
     CDS             complement(357970..358473)
                     /locus_tag="Smed_3904"
                     /note="KEGG: mes:Meso_3515 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312647.1"
                     /db_xref="GI:150376051"
                     /db_xref="GeneID:5318217"
                     /translation="MRTVNITLAAIMLCFVSIQAVSAQTKPTEPQEFARKMSMSNLFE
                     LKSAELARQRGEGRQVLEFAERMLADHARAGKELAEAARKDGVELSQSLDKAGQERLA
                     ALQALNGATFDPAYLSSQVTAHEDALELLKTYAERGEAGALKTFAESAYPTVRTHLLQ
                     VQSITSP"
     sig_peptide     complement(358402..358473)
                     /locus_tag="Smed_3904"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.881 at
                     residue 24"
     misc_feature    complement(357982..358383)
                     /locus_tag="Smed_3904"
                     /note="Domain of unknown function (DUF4142); Region:
                     DUF4142; pfam13628"
                     /db_xref="CDD:222272"
     gene            358652..358831
                     /locus_tag="Smed_3905"
                     /db_xref="GeneID:5318639"
     CDS             358652..358831
                     /locus_tag="Smed_3905"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312648.1"
                     /db_xref="GI:150376052"
                     /db_xref="GeneID:5318639"
                     /translation="MQTALFIAIPALPLGTALLLLWFGPLWRQQAAPWNRSSIWCHGS
                     PVLDRQGPWRTLDPT"
     gene            359037..359438
                     /locus_tag="Smed_3906"
                     /db_xref="GeneID:5318640"
     CDS             359037..359438
                     /locus_tag="Smed_3906"
                     /note="PFAM: Cupin 2 conserved barrel domain protein;
                     KEGG: sme:SMb20222 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cupin 2 domain-containing protein"
                     /protein_id="YP_001312649.1"
                     /db_xref="GI:150376053"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="GeneID:5318640"
                     /translation="MKTSRILAAALLAVGSGLALHAANAQQAGLHRTDLLQQDIGLPG
                     REAIQVRVDFDGGAVSIKHSHPGEEVAYVLEGSLEYQLEGRAPVTLNAGEALFIPAGV
                     AHVARNVGSGKASELATYIVEKGSPLVVPAE"
     sig_peptide     359037..359114
                     /locus_tag="Smed_3906"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.553 at
                     residue 26"
     misc_feature    359184..359396
                     /locus_tag="Smed_3906"
                     /note="Cupin domain; Region: Cupin_2; pfam07883"
                     /db_xref="CDD:219618"
     gene            359656..360393
                     /locus_tag="Smed_3907"
                     /db_xref="GeneID:5318641"
     CDS             359656..360393
                     /locus_tag="Smed_3907"
                     /note="PFAM: response regulator receiver; transcriptional
                     regulator domain protein;
                     KEGG: sme:SMb20219 putative response regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="two component transcriptional regulator"
                     /protein_id="YP_001312650.1"
                     /db_xref="GI:150376054"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR001867"
                     /db_xref="GeneID:5318641"
                     /translation="MEHIDHILIVDDDREIRELVSAYLKKNGLRATAVADGRQMRTFL
                     EANTVDLIVLDIMMPGDDGLVLSRELRVGRHKATPIVMLTARSDEMDRIIGLEMGADD
                     YLVKPFSARELLARIKAVLRRARMLPANLQVSEAGQLLRFGQWRLDTTARHLVDEDGT
                     AIALSGAEYRLLRVFVDHPQRVLNRDQLLNLTQGREAELFDRSIDLLVSRVRQRLGDD
                     AREPTYIKTVRSEGYVLSMPVEIVEPR"
     misc_feature    359656..360357
                     /locus_tag="Smed_3907"
                     /note="osmolarity response regulator; Provisional; Region:
                     ompR; PRK09468"
                     /db_xref="CDD:181883"
     misc_feature    359677..360018
                     /locus_tag="Smed_3907"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    order(359686..359691,359818..359820,359842..359844,
                     359905..359907,359962..359964,359971..359976)
                     /locus_tag="Smed_3907"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    359818..359820
                     /locus_tag="Smed_3907"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    order(359827..359832,359836..359844)
                     /locus_tag="Smed_3907"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    359971..359979
                     /locus_tag="Smed_3907"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    360073..360360
                     /locus_tag="Smed_3907"
                     /note="Effector domain of response regulator. Bacteria and
                     certain eukaryotes like protozoa and higher plants use
                     two-component signal transduction systems to detect and
                     respond to changes in the environment. The system consists
                     of a sensor histidine kinase and...; Region: trans_reg_C;
                     cd00383"
                     /db_xref="CDD:238225"
     misc_feature    order(360148..360150,360205..360210,360262..360264,
                     360271..360273,360295..360300,360334..360336,
                     360349..360351)
                     /locus_tag="Smed_3907"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238225"
     gene            360393..361718
                     /locus_tag="Smed_3908"
                     /db_xref="GeneID:5318642"
     CDS             360393..361718
                     /locus_tag="Smed_3908"
                     /note="PFAM: ATP-binding region ATPase domain protein;
                     histidine kinase HAMP region domain protein; histidine
                     kinase A domain protein;
                     KEGG: sme:SMb20218 putative sensor histidine kinase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane sensor signal transduction
                     histidine kinase"
                     /protein_id="YP_001312651.1"
                     /db_xref="GI:150376055"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003660"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="GeneID:5318642"
                     /translation="MVRRTGLGVNLWPHTLRARLFVILLAGLTIAHAMSFAVLFSERY
                     IAARSVMFNTLETDIATSIAILDRLPAAERASWLDRLARGSYRFVLGPGIPGDPVLTR
                     ADAEVADKVRAAIGAQYPIELESVPGGIRRLQAHLRLSDGEPLTIDVTPRGVMPVADW
                     LPFVLVAQLSLLVLCSWLAVRQATRPLADLARAADTLDPNSKTPRLSETGPREVAYAA
                     TAFNAMRDRIAQYLEERVQILAAISHDLQTPITRMKLRAEMADDSIERDKLIRDLEEV
                     ERLVKEGVAYARSAHGKDEKASRIDLASFVQSLAYDYQDTGKAVTVGELGDGTIVTRP
                     HALRRILTNLVDNALKFGGSAEIELQRRADGTVLIKVSDRGPGIPEDQLDAVLQPFFR
                     LEQSRNRDTGGTGLGLAIAQQLAIVIGASLTLRNRDGGGLAAELAIGAA"
     sig_peptide     360393..360506
                     /locus_tag="Smed_3908"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.913) with cleavage site probability 0.467 at
                     residue 38"
     misc_feature    360429..361628
                     /locus_tag="Smed_3908"
                     /note="heavy metal sensor kinase; Region: cztS_silS_copS;
                     TIGR01386"
                     /db_xref="CDD:233391"
     misc_feature    361086..361235
                     /locus_tag="Smed_3908"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    order(361104..361106,361116..361118,361128..361130,
                     361137..361139,361149..361151,361158..361160,
                     361209..361211,361215..361217,361227..361229)
                     /locus_tag="Smed_3908"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    361122..361124
                     /locus_tag="Smed_3908"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    361401..361673
                     /locus_tag="Smed_3908"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    order(361419..361421,361431..361433,361440..361442,
                     361503..361505,361509..361511,361515..361517,
                     361521..361526,361605..361616,361662..361664,
                     361668..361670)
                     /locus_tag="Smed_3908"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    361431..361433
                     /locus_tag="Smed_3908"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    order(361515..361517,361521..361523,361605..361607,
                     361611..361613)
                     /locus_tag="Smed_3908"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            complement(361799..362458)
                     /locus_tag="Smed_3909"
                     /db_xref="GeneID:5318643"
     CDS             complement(361799..362458)
                     /locus_tag="Smed_3909"
                     /note="PFAM: Glyoxalase/bleomycin resistance
                     protein/dioxygenase;
                     KEGG: sme:SMb20217 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance
                     protein/dioxygenase"
                     /protein_id="YP_001312652.1"
                     /db_xref="GI:150376056"
                     /db_xref="InterPro:IPR004360"
                     /db_xref="GeneID:5318643"
                     /translation="MTADSTRNAPVDMKLEIVVVPVSDIDRAKEFYTSLGWRLDADFA
                     GPDDYRVIQFTPPGSGASVIFGKHVTDAEPGSAQGLYLIVSDIEAAREALRGRGVDIS
                     EVFHAGDVHAGKDEPYLFGRLRVGGPDPERRSYRSYASFRDPDGNGWLLQEVTTRLPG
                     RVDASATTFSSAADLASAFRRAEAAHGEYEKQLGHRDEDWPVWYADYIVREQSGEPRP
                     S"
     misc_feature    complement(362000..362407)
                     /locus_tag="Smed_3909"
                     /note="This conserved domain belongs to a superfamily
                     including the bleomycin resistance protein, glyoxalase I,
                     and type I ring-cleaving dioxygenases; Region:
                     Glo_EDI_BRP_like_16; cd07263"
                     /db_xref="CDD:211353"
     misc_feature    complement(362012..362407)
                     /locus_tag="Smed_3909"
                     /note="Glyoxalase/Bleomycin resistance protein/Dioxygenase
                     superfamily; Region: Glyoxalase; pfam00903"
                     /db_xref="CDD:216182"
     gene            complement(362671..363717)
                     /locus_tag="Smed_3910"
                     /db_xref="GeneID:5318644"
     CDS             complement(362671..363717)
                     /locus_tag="Smed_3910"
                     /note="PFAM: alpha/beta hydrolase fold;
                     KEGG: sme:SMb20216 putative epoxide hydrolase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold protein"
                     /protein_id="YP_001312653.1"
                     /db_xref="GI:150376057"
                     /db_xref="InterPro:IPR000073"
                     /db_xref="InterPro:IPR000639"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5318644"
                     /translation="MTGEFNLPRRRFMRVAALAVAAAQFGMGRAALAESARGTSIPAT
                     APGTNTSFAEIKQVNAGVLNIGYAEAGRRDAPVVILLHGWPYDIHTYVDVAPLLAKAG
                     YRVIVPYLRGYGTTRFLSADTPRNGQQAAIAADIVALMDALGLDKAVVAGCDWGARTA
                     NIIAALWPERCKAMVSVSGYLIGSREANRMPLPPKAELAWWYQFYFATERGRAGYEQH
                     RNDFARLIWQLASPKWEFDDATFARSAAALENPDHVDITIHNYRWRISLADGEREFDE
                     LEDRLASLPVITVPTITLEGDANGAPHPDPAAYAKKFSGKYEHRLITGGIGHNLPQEA
                     PQAFAQAVVDADRL"
     sig_peptide     complement(363616..363717)
                     /locus_tag="Smed_3910"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.969 at
                     residue 34"
     misc_feature    complement(362677..363546)
                     /locus_tag="Smed_3910"
                     /note="Predicted hydrolases or acyltransferases
                     (alpha/beta hydrolase superfamily) [General function
                     prediction only]; Region: MhpC; COG0596"
                     /db_xref="CDD:223669"
     gene            complement(363994..364668)
                     /locus_tag="Smed_3911"
                     /db_xref="GeneID:5318645"
     CDS             complement(363994..364668)
                     /locus_tag="Smed_3911"
                     /note="PFAM: ThiJ/PfpI domain protein;
                     KEGG: sme:SMb20212 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ThiJ/PfpI domain-containing protein"
                     /protein_id="YP_001312654.1"
                     /db_xref="GI:150376058"
                     /db_xref="InterPro:IPR002818"
                     /db_xref="GeneID:5318645"
                     /translation="MKILMVLTSHDRLGDTGKPTGFWLEEFAAPYYVFKDAGAEVTLA
                     SPKGGQPPIDPKSDEPASQTAAMERFRDDPAARDRLANTLKLGDVRQEGYDAVFYPGG
                     HGPMWDLVEDRNSIALIEGFYDAGKPVAAVCHGPAVLTRVTHHGEPIVKGRRVTGFTN
                     SEEEAVQLTDVVPFLVEDELKRLGGRYEKAEDWADFTIVDGKLVTGQNPSSSTSAAME
                     LLKLLQ"
     misc_feature    complement(363997..364668)
                     /locus_tag="Smed_3911"
                     /note="Putative intracellular protease/amidase [General
                     function prediction only]; Region: ThiJ; COG0693"
                     /db_xref="CDD:223765"
     misc_feature    complement(364000..364662)
                     /locus_tag="Smed_3911"
                     /note="Type 1 glutamine amidotransferase (GATase1)-like
                     domain found in proteins similar to Escherichia coli Hsp31
                     protein; Region: GATase1_Hsp31_like; cd03141"
                     /db_xref="CDD:153235"
     misc_feature    complement(order(364180..364182,364267..364272))
                     /locus_tag="Smed_3911"
                     /note="potential catalytic triad [active]"
                     /db_xref="CDD:153235"
     misc_feature    complement(364270..364272)
                     /locus_tag="Smed_3911"
                     /note="conserved cys residue [active]"
                     /db_xref="CDD:153235"
     gene            364865..365812
                     /locus_tag="Smed_3912"
                     /db_xref="GeneID:5318646"
     CDS             364865..365812
                     /locus_tag="Smed_3912"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb20211 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001312655.1"
                     /db_xref="GI:150376059"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318646"
                     /translation="MDRIDAMKVFVAAIDEGSLAGAARRLKRSPTAVSRALSFLEAHV
                     GVELLHRTTRTLKLSEAGQRYAAACRRVLTDLEEADMLAGGESSAPRGILTISAPPIL
                     GEEILRPMLDDFLDLYPTVSARLLLLDRFVNLVDEGVDVALRIGHLADSSLISTRLGG
                     DVRRVVVASPGYLANHPRIEEPADLAKHQILAFTNFGLESWSFTPAMGSSIPRTVQFT
                     PRCIVNSVRAAAASAAAGRGLTRLYSYHVAEYVRDGRLEIVLAGAEHPPLPAHLLAPQ
                     GRMSVPKVRAFVDFAAPRLRSEFARMAAEAGKPIIPQVG"
     misc_feature    364871..365767
                     /locus_tag="Smed_3912"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    364874..365053
                     /locus_tag="Smed_3912"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    365138..365749
                     /locus_tag="Smed_3912"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     Region: PBP2_CrgA_like_2; cd08471"
                     /db_xref="CDD:176160"
     misc_feature    order(365168..365170,365180..365182,365297..365299,
                     365339..365341,365348..365350,365540..365542,
                     365591..365593,365672..365674)
                     /locus_tag="Smed_3912"
                     /note="putative effector binding pocket; other site"
                     /db_xref="CDD:176160"
     misc_feature    order(365171..365176,365186..365191,365195..365200,
                     365207..365209,365219..365221,365225..365245,
                     365429..365431,365522..365536,365555..365560,
                     365567..365569)
                     /locus_tag="Smed_3912"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176160"
     gene            365935..366648
                     /locus_tag="Smed_3913"
                     /db_xref="GeneID:5318647"
     CDS             365935..366648
                     /locus_tag="Smed_3913"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR;
                     KEGG: sme:SMb20210 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001312656.1"
                     /db_xref="GI:150376060"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR002424"
                     /db_xref="GeneID:5318647"
                     /translation="MSNEQKVVIVTGASQGIGAGLVRAYRDRNYRVVATSRSIKPSGD
                     PDIHTVAGDISKPETAERIVREGIEHFGRIDSLVNNAGVFLAKPFIEMTQEDYEHNLG
                     VNVAGFFHITQRAAVEMLKQGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRS
                     LAMEFSRSGVRVNAVSPGVIKTPMHPIETHSALAALHPVGRMGDISDVVGAVLYLENA
                     GFITGEILHVDGGQNAGRW"
     misc_feature    365935..366627
                     /locus_tag="Smed_3913"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Validated; Region: fabG; PRK05557"
                     /db_xref="CDD:235500"
     misc_feature    365956..366621
                     /locus_tag="Smed_3913"
                     /note="classical (c) SDRs; Region: SDR_c; cd05233"
                     /db_xref="CDD:212491"
     misc_feature    order(365968..365970,365974..365985,366040..366048,
                     366088..366096,366172..366180,366241..366243,
                     366322..366330,366373..366375,366385..366387,
                     366463..366474,366478..366483)
                     /locus_tag="Smed_3913"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:212491"
     misc_feature    order(366244..366246,366328..366330,366373..366375,
                     366385..366387)
                     /locus_tag="Smed_3913"
                     /note="active site"
                     /db_xref="CDD:212491"
     gene            366695..366934
                     /locus_tag="Smed_3914"
                     /db_xref="GeneID:5318648"
     CDS             366695..366934
                     /locus_tag="Smed_3914"
                     /note="PFAM: 4-oxalocrotonate tautomerase;
                     KEGG: sme:SMb20209 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="YP_001312657.1"
                     /db_xref="GI:150376061"
                     /db_xref="InterPro:IPR004370"
                     /db_xref="GeneID:5318648"
                     /translation="MPIVTVQVTREGSAPGRNSVTAEEKAAIIKGVSEVLLDVLKKPL
                     ESTYVVIEEVDLDNWGWGGLPTVQYRRQRVEAAKS"
     misc_feature    366695..366913
                     /locus_tag="Smed_3914"
                     /note="Uncharacterized protein, 4-oxalocrotonate
                     tautomerase homolog [General function prediction only];
                     Region: COG1942"
                     /db_xref="CDD:224853"
     misc_feature    order(366698..366703,366830..366832)
                     /locus_tag="Smed_3914"
                     /note="active site 1 [active]"
                     /db_xref="CDD:238274"
     misc_feature    order(366698..366718,366776..366778,366785..366790,
                     366797..366799,366809..366814)
                     /locus_tag="Smed_3914"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238274"
     misc_feature    order(366707..366709,366713..366715,366767..366772,
                     366779..366784,366791..366793,366824..366829,
                     366833..366847,366851..366856,366863..366883)
                     /locus_tag="Smed_3914"
                     /note="hexamer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238274"
     misc_feature    order(366713..366715,366869..366871)
                     /locus_tag="Smed_3914"
                     /note="active site 2 [active]"
                     /db_xref="CDD:238274"
     gene            complement(366981..368108)
                     /locus_tag="Smed_3915"
                     /db_xref="GeneID:5318700"
     CDS             complement(366981..368108)
                     /locus_tag="Smed_3915"
                     /note="TIGRFAM: coenzyme PQQ biosynthesis protein E;
                     PFAM: Radical SAM domain protein;
                     SMART: Elongator protein 3/MiaB/NifB;
                     KEGG: sme:SMb20208 probable pyrroloquinoline quinone
                     synthesis protein E"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="YP_001312658.1"
                     /db_xref="GI:150376062"
                     /db_xref="InterPro:IPR006638"
                     /db_xref="InterPro:IPR007197"
                     /db_xref="InterPro:IPR011843"
                     /db_xref="GeneID:5318700"
                     /translation="MSDTIARPADAVVAAPRVPPPMAMLAELTHRCPLACPYCSNPIA
                     LTQAKEELSTDEWVDVFAQAADLGVLHLHLSGGEPASRRDLVDLTQAAGSLGLYTNLI
                     TSGVGLTEARMNSLAEAGLDHIQLSIQGVSPESADRIGGYRGGYERKMAVAGWATNAA
                     IPLTLNAVCHRQNMGEIDEIIELAFLLKARRVEIATVQFHGWAERNKELLMPTREQVE
                     RATRTVAEAREAYQGILVIDYVPADYYSKYPKACMGGWGRVGLNITPSGRVLPCHAAE
                     TIPSLSFENVRDSALSKIWYDSDAFNAYRGEDWMPELCRNCDRKKVDFGGCRCQAMTL
                     AGDASATDPVCIRSPLRDRLTREVEQLAAPSTTTTNYRGRA"
     misc_feature    complement(366984..368036)
                     /locus_tag="Smed_3915"
                     /note="pyrroloquinoline quinone biosynthesis protein PqqE;
                     Provisional; Region: PRK05301"
                     /db_xref="CDD:235397"
     misc_feature    complement(367491..368030)
                     /locus_tag="Smed_3915"
                     /note="Radical SAM superfamily. Enzymes of this family
                     generate radicals by combining a 4Fe-4S cluster and
                     S-adenosylmethionine (SAM) in close proximity. They are
                     characterized by a conserved CxxxCxxC motif, which
                     coordinates the conserved iron-sulfur cluster; Region:
                     Radical_SAM; cd01335"
                     /db_xref="CDD:100105"
     misc_feature    complement(order(367509..367514,367605..367607,
                     367728..367730,367797..367805,367875..367880,
                     367884..367886,367989..367997,368001..368003,
                     368007..368009,368013..368015))
                     /locus_tag="Smed_3915"
                     /note="FeS/SAM binding site; other site"
                     /db_xref="CDD:100105"
     misc_feature    complement(367074..367328)
                     /locus_tag="Smed_3915"
                     /note="radical SAM additional 4Fe4S-binding SPASM domain;
                     Region: rSAM_more_4Fe4S; TIGR04085"
                     /db_xref="CDD:234461"
     gene            complement(368105..368401)
                     /locus_tag="Smed_3916"
                     /db_xref="GeneID:5318701"
     CDS             complement(368105..368401)
                     /locus_tag="Smed_3916"
                     /note="PFAM: coenzyme PQQ synthesis D;
                     KEGG: sme:SMb20207 putative pyrroloquinoline quinone
                     synthesis protein D"
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme PQQ synthesis D"
                     /protein_id="YP_001312659.1"
                     /db_xref="GI:150376063"
                     /db_xref="InterPro:IPR008792"
                     /db_xref="GeneID:5318701"
                     /translation="MTADQPMISGSSVVKLARGVRLHEDTVRGQTVLLAPERAMAVDD
                     IAVAIVQALDGERTLDDIAAGFAEKFDAPVAEIAGDVTAFVQELSVRRMLEIVQ"
     misc_feature    complement(368117..368359)
                     /locus_tag="Smed_3916"
                     /note="Coenzyme PQQ synthesis protein D (PqqD); Region:
                     PqqD; pfam05402"
                     /db_xref="CDD:218577"
     gene            complement(368398..369168)
                     /locus_tag="Smed_3917"
                     /db_xref="GeneID:5318702"
     CDS             complement(368398..369168)
                     /locus_tag="Smed_3917"
                     /EC_number="1.3.3.11"
                     /note="Required in the synthesis of PPQ, but its exact
                     function is unknown"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqC"
                     /protein_id="YP_001312660.1"
                     /db_xref="GI:150376064"
                     /db_xref="InterPro:IPR002110"
                     /db_xref="InterPro:IPR004305"
                     /db_xref="InterPro:IPR011845"
                     /db_xref="GeneID:5318702"
                     /translation="MTTADDRQAFHARLLEIGKQRYHDKHPFHAMLHSGGCTTTQVRA
                     WVINRYYYQSRIPMKDAAFMSRCDDPDLRRAWRSRIEDHDGDVEEGGGIRRWLRLAEA
                     VGLDPTYVASTKGVLPSTRFAVDAYVSFVREKPLLEAVASSLTELFAPRIHSERIAGL
                     LEHYAFADESALAYFRQRLAEAPRDVEFGLAFVLDRADTREKQDAAAAALAFKTDVLW
                     SQLDALYSAYVSPGRIPPGGWDGTEGVVREPRAREAAE"
     misc_feature    complement(368437..369168)
                     /locus_tag="Smed_3917"
                     /note="pyrroloquinoline quinone biosynthesis protein PqqC;
                     Provisional; Region: PRK05157"
                     /db_xref="CDD:235353"
     gene            complement(369165..370076)
                     /locus_tag="Smed_3918"
                     /db_xref="GeneID:5318703"
     CDS             complement(369165..370076)
                     /locus_tag="Smed_3918"
                     /note="possibly involved in transport of pyrroloquinoline
                     quinone transport"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="YP_001312661.1"
                     /db_xref="GI:150376065"
                     /db_xref="InterPro:IPR011842"
                     /db_xref="GeneID:5318703"
                     /translation="MNKTPDLRILVLGAAAGGGLPQWNCGCPNCAMARDPGSGLKPQT
                     QSSLAVSLDGEAWAVFNASPDIRQQIHANRPLQPRRLRHSPIESVVLTNGDIDHLAGL
                     LVLREKQAFALFSTGAVGRIVADNPVFQVLDPELVSKRTIEIEETFSPLQGLGARLFA
                     VPGKVPLFLENGEPDLGLEGEHTVGVELAAAGKRVYYVPGCAVMTDALAARLRNADAV
                     FFDGTLYSDDEMIQTGMGRKTGRRMGHMPIDGEGGSLDALGTLNIRRKIYVHINNTNP
                     IWRAGSERERVEAQGFEIGYDGMEVRL"
     misc_feature    complement(369168..370058)
                     /locus_tag="Smed_3918"
                     /note="pyrroloquinoline quinone biosynthesis protein PqqB;
                     Provisional; Region: PRK05184"
                     /db_xref="CDD:235361"
     misc_feature    complement(369168..370055)
                     /locus_tag="Smed_3918"
                     /note="coenzyme PQQ biosynthesis protein B; Region:
                     PQQ_syn_pqqB; TIGR02108"
                     /db_xref="CDD:233731"
     gene            complement(370585..371526)
                     /locus_tag="Smed_3919"
                     /db_xref="GeneID:5318704"
     CDS             complement(370585..371526)
                     /locus_tag="Smed_3919"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb20203 probable transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001312662.1"
                     /db_xref="GI:150376066"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318704"
                     /translation="MRNVSLRQLRTVEAVCRLGKINLAAEALGLTGPALTLQIQHLER
                     DTGVALFDRTRGGMVPTAYGLAFLEAARAVEDSLAALEDSIGAISGLRTGRLRLGVVS
                     TGKYFAPQLIAAFRDQVPAVEINLFIGNRAEIIAKLRDHEIDIALMGRPPRDFEVRAQ
                     VFGDHPLVFIAPAGHPLAGVLEISRERIAREQFLVREKGSGTRISLEIFLSDTPHELE
                     ELGTEIASNETIKQAVIAGLGIAFISAHTIEQEVKLGRLVILDVIDTPIRRQWFTVSR
                     LDRAATPAMQAFEQFVLSSGARYLPVVSKPYPANAFG"
     misc_feature    complement(370624..371514)
                     /locus_tag="Smed_3919"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    complement(371335..371511)
                     /locus_tag="Smed_3919"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    complement(370651..371244)
                     /locus_tag="Smed_3919"
                     /note="The C-terminal substrate binding of LysR-type
                     transcriptional regulator (CbbR) of RubisCO operon, which
                     is involved in the carbon dioxide fixation, contains the
                     type 2 periplasmic binding fold; Region:
                     PBP2_CbbR_RubisCO_like; cd08419"
                     /db_xref="CDD:176111"
     misc_feature    complement(order(370819..370824,370828..370833,
                     370849..370866,371143..371163,371167..371169,
                     371179..371181,371188..371193,371197..371202))
                     /locus_tag="Smed_3919"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176111"
     gene            371628..372677
                     /locus_tag="Smed_3920"
                     /db_xref="GeneID:5318705"
     CDS             371628..372677
                     /locus_tag="Smed_3920"
                     /EC_number="3.1.3.11"
                     /note="catalyzes the formation of D-fructose 6-phosphate
                     from fructose-1,6-bisphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="YP_001312663.1"
                     /db_xref="GI:150376067"
                     /db_xref="InterPro:IPR000146"
                     /db_xref="GeneID:5318705"
                     /translation="MSGATLEAYLASCTTHGDELSRDVAAVIQRLAKAALDIRKLVNQ
                     GALGTVFNGMHSGSNTDGDVQKDLDILCDDQFLSCLQGAPVACYASEELENPVLLDPA
                     ARLAVAIDPLDGSSNIDNNISIGTIFSVLPAAKGPDVDPSQSFLQPGNRQLAAGFFVY
                     GPQTALVLSLGRGTEIFIFSSRLGCFVDAYKSVGIPDRANEFAINMSNYRHWEEAIRL
                     YVDDCLAGSEGPRERDFNMRWIASLVAEAYRILVRGGIFLYPADSRKGYSHGRIRLVY
                     EANPIAFIVENAGGSATTSVDRILDLVPESLHQRVPLVFGSRREVARITRYHVDPNMI
                     GERAPLFGKRGLFRA"
     misc_feature    371640..372608
                     /locus_tag="Smed_3920"
                     /note="fructose-1,6-bisphosphatase family protein; Region:
                     PLN02628"
                     /db_xref="CDD:215337"
     misc_feature    371682..372611
                     /locus_tag="Smed_3920"
                     /note="Fructose-1,6-bisphosphatase, an enzyme that
                     catalyzes the hydrolysis of fructose-1,6-biphosphate  into
                     fructose-6-phosphate and is critical in gluconeogenesis
                     pathway. The alignment model also includes chloroplastic
                     FBPases and sedoheptulose-1; Region: FBPase; cd00354"
                     /db_xref="CDD:238214"
     misc_feature    order(371688..371690,371694..371702,371937..371942,
                     372021..372023)
                     /locus_tag="Smed_3920"
                     /note="AMP binding site [chemical binding]; other site"
                     /db_xref="CDD:238214"
     misc_feature    order(371832..371834,371898..371903,371955..371957,
                     371961..371963,372456..372458)
                     /locus_tag="Smed_3920"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:238214"
     misc_feature    order(371964..371966,371970..371975,372249..372251,
                     372339..372344,372354..372356,372402..372404,
                     372438..372440)
                     /locus_tag="Smed_3920"
                     /note="active site"
                     /db_xref="CDD:238214"
     gene            372688..373557
                     /locus_tag="Smed_3921"
                     /db_xref="GeneID:5318706"
     CDS             372688..373557
                     /locus_tag="Smed_3921"
                     /EC_number="2.7.1.19"
                     /note="PFAM: phosphoribulokinase/uridine kinase;
                     KEGG: sme:SMb20201 putative phosphoribulokinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="YP_001312664.1"
                     /db_xref="GI:150376068"
                     /db_xref="InterPro:IPR006082"
                     /db_xref="InterPro:IPR006083"
                     /db_xref="GeneID:5318706"
                     /translation="MSAKYPIISITGSSGAGTTTVKDTFEKIFKRENISASFIEGDAF
                     HRYDRETMRSKIAEEKARGVDFTHFSAEANELEILESVFAEYGRRGVGRTRHYVHDDA
                     EAVKFGSDPGTFTDWEEFRDSDLLFYEGLHGCAVTDTINLAQHCDLKIGVVPVINLEW
                     IQKIHRDKATRGYSTEAVTDTILRRMPDYVHYICPQFSLTDINFQRVPIVDTSNPFIA
                     RWIPTPAESILVIRFAKPQSIDFPYLLSMLHNSYMSRANSIVVPGDKLDLAMQLIFTP
                     LIHKLLERKHRMS"
     misc_feature    372688..373548
                     /locus_tag="Smed_3921"
                     /note="phosphoribulokinase; Provisional; Region: PRK15453"
                     /db_xref="CDD:237970"
     gene            373568..375655
                     /locus_tag="Smed_3922"
                     /db_xref="GeneID:5318707"
     CDS             373568..375655
                     /locus_tag="Smed_3922"
                     /EC_number="2.2.1.1"
                     /note="catalyzes the formation of ribose 5-phosphate and
                     xylulose 5-phosphate from sedoheptulose 7-phosphate and
                     glyceraldehyde 3-phosphate; can transfer ketol groups
                     between several groups; in Escherichia coli there are two
                     tkt genes, tktA expressed during exponential growth and
                     the tktB during stationary phase"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="YP_001312665.1"
                     /db_xref="GI:150376069"
                     /db_xref="InterPro:IPR005474"
                     /db_xref="InterPro:IPR005475"
                     /db_xref="InterPro:IPR005476"
                     /db_xref="InterPro:IPR005478"
                     /db_xref="GeneID:5318707"
                     /translation="MNVSQQIEPRAAASERNMADAIRFLSMDAVEKANSGHPGMPMGM
                     ADAVTVLFNRFIRIDPSLPDWPDRDRFVLSAGHGSMLLYSLHHLIGFADMPMAELSSF
                     RQLGSKTAGHPEYGHALGIETTTGPLGQGISTAVGMAMAEQMMASRFGSALCNHFTYV
                     VAGDGCLQEGISHEAIDLAGHLKLRKLVVLWDDNRISIDGSTDLSTSMNQLARFRAAS
                     WDAQAVDGHDPEAVAKALERARRTRKPSLIACRTRIGKGAASMEGSHKTHGAALGDKE
                     IAATREKLGWPHPPFFVPPEIRAAWAKVAARGRTAREAWDIRLDASRSKKRYEQTIRR
                     QFDGELGDLLAKFRSAHRTRATKVATRQASQMALEVINGATALTIGGSADLTGSNLTM
                     TSQTQPISPGNFKGRYLHYGIREHGMAAAMNGIALHGGFIPYGGTFLVFSDYARGAMR
                     LSALMGLPVIYVLTHDSIGLGEDGPTHQPVEHLAMLRATPNLNVFRPADIIETAECWE
                     IALGEKNTPSVLALSRQALPMLRRTEGNENQSALGAYVLREARGNRDITILATGSEVE
                     IAVAAAERLQAEEGIAAAVVSMPCWEKFEVQDLAYRRKVLGDAPRIAIEAAGRLGWDR
                     WMGPDGAFVGMTGFGASAPAGDLYRHFGITADHVVAEALELLRRAYSETLPIGARIGP
                     HPSAHTVRSSQEA"
     misc_feature    373607..375568
                     /locus_tag="Smed_3922"
                     /note="Transketolase [Carbohydrate transport and
                     metabolism]; Region: TktA; COG0021"
                     /db_xref="CDD:223100"
     misc_feature    373625..374410
                     /locus_tag="Smed_3922"
                     /note="Thiamine pyrophosphate (TPP) family, Transketolase
                     (TK) subfamily, TPP-binding module; TK catalyzes the
                     transfer of a two-carbon unit from ketose phosphates to
                     aldose phosphates. In heterotrophic organisms, TK provides
                     a link between glycolysis and the...; Region: TPP_TK;
                     cd02012"
                     /db_xref="CDD:238970"
     misc_feature    order(373796..373798,373943..373945,373949..373951,
                     374057..374062,374072..374074,374147..374149,
                     374153..374155,374159..374161,374369..374371)
                     /locus_tag="Smed_3922"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238970"
     misc_feature    order(373874..373876,373898..373903,373907..373909,
                     373946..373951,373955..373957,374066..374077,
                     374084..374089,374096..374098,374108..374110,
                     374156..374161,374204..374206)
                     /locus_tag="Smed_3922"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238970"
     misc_feature    374702..375139
                     /locus_tag="Smed_3922"
                     /note="Pyrimidine (PYR) binding domain of
                     1-deoxy-D-xylulose-5-phosphate synthase (DXS),
                     transketolase (TK), and related proteins; Region:
                     TPP_PYR_DXS_TK_like; cd07033"
                     /db_xref="CDD:132916"
     misc_feature    order(374717..374719,374786..374788,374795..374797,
                     374801..374818,374825..374830,374834..374842,
                     374897..374899,374906..374911,374984..374986,
                     374993..374995,375041..375046,375110..375112)
                     /locus_tag="Smed_3922"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    order(374717..374719,374795..374797,374804..374812,
                     374894..374899,374903..374905,374984..374986,
                     374990..374992,375017..375022,375026..375031,
                     375035..375037)
                     /locus_tag="Smed_3922"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    order(374804..374806,374810..374812,374888..374890,
                     374897..374899)
                     /locus_tag="Smed_3922"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132916"
     misc_feature    375197..375541
                     /locus_tag="Smed_3922"
                     /note="Transketolase, C-terminal domain; Region:
                     Transketolase_C; pfam02780"
                     /db_xref="CDD:217227"
     gene            375658..376737
                     /locus_tag="Smed_3923"
                     /db_xref="GeneID:5318708"
     CDS             375658..376737
                     /locus_tag="Smed_3923"
                     /EC_number="4.1.2.13"
                     /note="class II aldolase; catalyzes the reversible aldol
                     condensation of dihydroxyacetonephosphate and
                     glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis
                     and gluconeogenesis"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphate aldolase"
                     /protein_id="YP_001312666.1"
                     /db_xref="GI:150376070"
                     /db_xref="InterPro:IPR000771"
                     /db_xref="InterPro:IPR006412"
                     /db_xref="GeneID:5318708"
                     /translation="MARITLRQLLDHAAERSYGVPAFNINNMEQGLAIMEAARACDAP
                     VILQVSRGARSYANDIMLAKMMEALEVMYPDIPLCIHQDHGNNVATCLTAIQHGFTSV
                     MMDGSLKEDAKTPADYAYNAMITTEVSRLAHMVGASVEGELGCLGSLETGHGEAEDGH
                     GFEGALDRSQLLTDPDEAARFVAETGVDALAVAIGTSHGAYKFTRKPTGEVLAMDVIE
                     KIHERLPDTHIVMHGSSSVPQEWQDVFNAHGGEMRETYGVPVEEIVRGIRFGVRKVNI
                     DTDLRLAAAAAFRRVADTSRTEFDPRKFLKPAMDAMSAVCKARFEAFGTAGNASRIKV
                     VPMAEMARRYASGSLKPQAKRAEAA"
     misc_feature    375673..376638
                     /locus_tag="Smed_3923"
                     /note="fructose-bisphosphate aldolase; Provisional;
                     Region: PRK09197"
                     /db_xref="CDD:236406"
     misc_feature    375673..376638
                     /locus_tag="Smed_3923"
                     /note="Tagatose-1,6-bisphosphate (TBP) aldolase and
                     related Type B Class II aldolases. TBP aldolase is a
                     tetrameric class II aldolase that catalyzes the reversible
                     condensation of dihydroxyacetone phosphate with
                     glyceraldehyde 3-phsophate to produce tagatose 1; Region:
                     TBP_aldolase_IIB; cd00947"
                     /db_xref="CDD:238477"
     misc_feature    order(375736..375744,375751..375753,375811..375813,
                     375820..375828,375838..375840,375850..375852,
                     375859..375864,376105..376107,376489..376494,
                     376498..376503,376510..376512,376522..376524,
                     376531..376533)
                     /locus_tag="Smed_3923"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238477"
     misc_feature    order(375904..375909,376246..376254,376258..376260,
                     376351..376356,376360..376362,376480..376482,
                     376486..376491)
                     /locus_tag="Smed_3923"
                     /note="active site"
                     /db_xref="CDD:238477"
     misc_feature    order(375907..375909,376249..376251,376351..376353)
                     /locus_tag="Smed_3923"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:238477"
     misc_feature    order(376246..376248,376252..376254,376258..376260,
                     376354..376356,376360..376362)
                     /locus_tag="Smed_3923"
                     /note="Na+ binding site [ion binding]; other site"
                     /db_xref="CDD:238477"
     gene            376768..378228
                     /gene="rbcL"
                     /locus_tag="Smed_3924"
                     /db_xref="GeneID:5318709"
     CDS             376768..378228
                     /gene="rbcL"
                     /locus_tag="Smed_3924"
                     /EC_number="4.1.1.39"
                     /note="type III RuBisCO; involved in carbon fixation"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose bisophosphate carboxylase"
                     /protein_id="YP_001312667.1"
                     /db_xref="GI:150376071"
                     /db_xref="InterPro:IPR000685"
                     /db_xref="GeneID:5318709"
                     /translation="MNADAKTEIKGRERYKAGVLKYAQMGYWNGDYEPKDTDLIALFR
                     ITPQDGVDPIEAAAAVAGESSTATWTVVWTDRLTACDQYRAKAYRVDPVPGTPGQYFC
                     YVAYDLILFEEGSIANLTASIIGNVFSFKPLKAARLEDMRLPVAYVKTFKGPPTGIVV
                     ERERLDKFGKPLLGATTKPKLGLSGKNYGRVVYEGLKGGLDFMKDDENINSQPFMHWR
                     DRYLYCMEAVNHASAVTGEVKGHYLNVTAGTMEEMYRRAEFAKELGSVIVMVDLIIGW
                     TAIQSMSEWCRQNDMILHMHRAGHGTYTRQKNHGISFRVIAKWLRLAGVDHLHAGTAV
                     GKLEGDPLTVQGYYNVCREMKNAVDLPRGLFFEQDWADLKKVLPVASGGIHAGQMHQL
                     LDLFGDDVVLQFGGGTIGHPMGIQAGATANRVALEAMVLARNEGRDIAHEGPEILRAA
                     AKWCKPLEAALDTWGNISFNYTPTDTSDFVPSVTAA"
     misc_feature    376795..378198
                     /gene="rbcL"
                     /locus_tag="Smed_3924"
                     /note="ribulose bisophosphate carboxylase; Reviewed;
                     Region: rbcL; PRK04208"
                     /db_xref="CDD:179787"
     misc_feature    376843..378192
                     /gene="rbcL"
                     /locus_tag="Smed_3924"
                     /note="Ribulose bisphosphate carboxylase large chain, Form
                     I; Region: RuBisCO_large_I; cd08212"
                     /db_xref="CDD:173977"
     misc_feature    order(376909..376911,376954..376956,376960..376965,
                     376969..376992,376999..377001,377014..377016,
                     377092..377106,377110..377112,377116..377121,
                     377128..377133,377137..377145,377149..377160,
                     377164..377172,377299..377313,377386..377391,
                     377395..377409,377413..377415,377503..377520,
                     377533..377535,377578..377580,377587..377601,
                     377605..377610,377653..377655,377659..377664,
                     377668..377676,377680..377685,377692..377700,
                     377764..377781,377914..377922,377983..377988,
                     377992..378003,378007..378012,378157..378159,
                     378166..378168,378172..378174,378178..378183,
                     378187..378189)
                     /gene="rbcL"
                     /locus_tag="Smed_3924"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:173977"
     misc_feature    order(376954..376956,376969..376974,377143..377145,
                     377293..377295,377299..377301,377305..377307,
                     377383..377388,377653..377658,377752..377754,
                     377773..377778,377908..377916,377980..377985)
                     /gene="rbcL"
                     /locus_tag="Smed_3924"
                     /note="active site"
                     /db_xref="CDD:173977"
     misc_feature    order(377242..377244,377257..377259,377263..377277,
                     377356..377364,377452..377454,377461..377481,
                     377548..377550,377563..377565,377638..377640,
                     377962..377964,378001..378006,378016..378018,
                     378025..378027,378034..378039,378046..378051,
                     378058..378060,378064..378072,378124..378126,
                     378130..378132)
                     /gene="rbcL"
                     /locus_tag="Smed_3924"
                     /note="heterodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:173977"
     misc_feature    377377..377379
                     /gene="rbcL"
                     /locus_tag="Smed_3924"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:173977"
     misc_feature    377383..377388
                     /gene="rbcL"
                     /locus_tag="Smed_3924"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:173977"
     gene            378252..378641
                     /locus_tag="Smed_3925"
                     /db_xref="GeneID:5318761"
     CDS             378252..378641
                     /locus_tag="Smed_3925"
                     /EC_number="4.1.1.39"
                     /note="PFAM: ribulose bisphosphate carboxylase small
                     chain;
                     KEGG: sme:SMb20197 putative ribulose-1,5-bisphosphate
                     carboxylase small subunit protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-bisphosphate carboxylase"
                     /protein_id="YP_001312668.1"
                     /db_xref="GI:150376072"
                     /db_xref="InterPro:IPR000894"
                     /db_xref="GeneID:5318761"
                     /translation="MRITQGCFSFLPDLTDEQITAQVEYCLGRGWAIGVEYTDDPHPR
                     NTYWEMWGNPMFDLRDAKGVMMEVEDCRKAHPQDYIRLNAFDSSRGLETVTMSFIVNR
                     PENEPSLRMTRTESDGRSQHYTWETQR"
     misc_feature    378258..378560
                     /locus_tag="Smed_3925"
                     /note="Ribulose bisphosphate carboxylase/oxygenase
                     (Rubisco), small subunit. Rubisco is a bifunctional enzyme
                     catalyzes the initial steps of two opposing metabolic
                     pathways: photosynthetic carbon fixation and the competing
                     process of photorespiration. Rubisco...; Region:
                     RuBisCO_small; cd03527"
                     /db_xref="CDD:239603"
     misc_feature    order(378258..378263,378267..378281,378285..378287,
                     378291..378293,378315..378317,378324..378326,
                     378357..378359,378384..378392,378396..378401,
                     378474..378476,378525..378527,378531..378536)
                     /locus_tag="Smed_3925"
                     /note="multimerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239603"
     gene            378652..379587
                     /locus_tag="Smed_3926"
                     /db_xref="GeneID:5318762"
     CDS             378652..379587
                     /locus_tag="Smed_3926"
                     /note="TIGRFAM: CbxX/CfqX monofunctional;
                     PFAM: AAA ATPase central domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20196 probable CbbX protein"
                     /codon_start=1
                     /transl_table=11
                     /product="protein CbxX/CfqX"
                     /protein_id="YP_001312669.1"
                     /db_xref="GI:150376073"
                     /db_xref="InterPro:IPR000470"
                     /db_xref="InterPro:IPR000641"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR003959"
                     /db_xref="GeneID:5318762"
                     /translation="MLMPDAPTTTESLPTSVDLAEEYQASGVAEILDELDRELVGLKP
                     VKQRIRETAALLLVERARRAMGLSHEPPSLHMSFTGNPGTGKTTVALRMANLLHRLGY
                     IRKGHLVSVTRDDLVGQYIGHTAPKTKEILKKAMGGVLFIDEAYYLYRPDNERDYGQE
                     AIEILLQVMENNRDDLVVILAGYADRMDRFFESNPGFRSRIAHHIDFPDYDNGELLSI
                     AESMLSRQGYRFDAKASAVMGDYIERRRCQPHFANARSIRNALDRARLRQANRLFEES
                     AGPVDAEQLSTITARDISASRVFAAGEPSHKETTP"
     misc_feature    378697..379548
                     /locus_tag="Smed_3926"
                     /note="probable Rubsico expression protein CbbX; Region:
                     cbbX_cfxQ; TIGR02880"
                     /db_xref="CDD:200217"
     misc_feature    378862..379275
                     /locus_tag="Smed_3926"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    378889..378912
                     /locus_tag="Smed_3926"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(378892..378915,379078..379080,379198..379200)
                     /locus_tag="Smed_3926"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    379066..379083
                     /locus_tag="Smed_3926"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    379249..379251
                     /locus_tag="Smed_3926"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     gene            379584..380270
                     /locus_tag="Smed_3927"
                     /db_xref="GeneID:5318763"
     CDS             379584..380270
                     /locus_tag="Smed_3927"
                     /EC_number="5.1.3.1"
                     /note="PFAM: ribulose-phosphate 3-epimerase; Orotidine
                     5'-phosphate decarboxylase;
                     KEGG: sme:SMb20195 putative
                     pentose-5-phosphate-3-epimerase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="YP_001312670.1"
                     /db_xref="GI:150376074"
                     /db_xref="InterPro:IPR000056"
                     /db_xref="InterPro:IPR001754"
                     /db_xref="GeneID:5318763"
                     /translation="MNETTIIAPSVLSADFSRLGEEVEAVCRAGADWIHLDVMDGHFV
                     PNITFGPPVIKALRDRTDKVFDCHLMIAPPTPYLGAFACAGCDIITVHAEATTHLDRT
                     LQAIRDVGCKAGVSLNPSTPESVIEYVLDRLDLVLLMTVNPGFGGQDFIPAVIEKVRR
                     VKSLIGNRPIHIEIDGGVTPETAPLVAAAGADVLVAGSAVFKGGSEEHYARNITAIRA
                     ASDGAIRKAA"
     misc_feature    379593..380252
                     /locus_tag="Smed_3927"
                     /note="Pentose-5-phosphate-3-epimerase [Carbohydrate
                     transport and metabolism]; Region: Rpe; COG0036"
                     /db_xref="CDD:223114"
     misc_feature    379599..380129
                     /locus_tag="Smed_3927"
                     /note="Ribulose-5-phosphate 3-epimerase (RPE). This enzyme
                     catalyses the interconversion of D-ribulose 5-phosphate
                     (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin
                     cycle (reductive pentose phosphate pathway) in
                     chloroplasts and in the oxidative pentose...; Region: RPE;
                     cd00429"
                     /db_xref="CDD:238244"
     misc_feature    order(379611..379613,379617..379619,379692..379694,
                     379791..379793,380010..380015,380019..380024,
                     380106..380108,380112..380114)
                     /locus_tag="Smed_3927"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238244"
     misc_feature    order(379632..379634,379641..379643,379701..379703,
                     379707..379712,379716..379718,379722..379733,
                     379800..379802,379812..379814,379875..379877,
                     379881..379886,379938..379940,379947..379949,
                     379953..379955,379965..379967,380007..380009,
                     380034..380036,380040..380042,380052..380054)
                     /locus_tag="Smed_3927"
                     /note="hexamer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238244"
     misc_feature    order(379686..379688,379692..379694,379785..379787,
                     380106..380108)
                     /locus_tag="Smed_3927"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:238244"
     gene            380274..380840
                     /locus_tag="Smed_3928"
                     /db_xref="GeneID:5318764"
     CDS             380274..380840
                     /locus_tag="Smed_3928"
                     /note="PFAM: alkyl hydroperoxide reductase/ Thiol specific
                     antioxidant/ Mal allergen; Redoxin domain protein;
                     KEGG: sme:SMb20194 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase"
                     /protein_id="YP_001312671.1"
                     /db_xref="GI:150376075"
                     /db_xref="InterPro:IPR000866"
                     /db_xref="InterPro:IPR011594"
                     /db_xref="InterPro:IPR013740"
                     /db_xref="GeneID:5318764"
                     /translation="MAATPPLCDFGRPAIDARLPGVDGSSHSIFDQAGPKGLVLAFIC
                     NHCPYVKAVIARIVRDASDLRAHGVGFVAINSNDSGNYPQDSFENMKRFASQNALPFP
                     YLHDEDQSVAKAYGAVCTPDFFGFNKDMRLQYRGRLDASRKEIGPADLRRDLYEAMVM
                     VAMFGKGPAEQQPSIGCTIKWKVSAFQV"
     misc_feature    380304..380816
                     /locus_tag="Smed_3928"
                     /note="Peroxiredoxin (PRX)-like 1 family; hypothetical
                     proteins that show sequence similarity to PRXs. Members of
                     this group contain a conserved cysteine that aligns to the
                     first cysteine in the CXXC motif of TRX. This does not
                     correspond to the peroxidatic...; Region: PRX_like1;
                     cd02969"
                     /db_xref="CDD:239267"
     misc_feature    380412..380414
                     /locus_tag="Smed_3928"
                     /note="putative catalytic residue [active]"
                     /db_xref="CDD:239267"
     gene            complement(381061..381993)
                     /locus_tag="Smed_3929"
                     /db_xref="GeneID:5318765"
     CDS             complement(381061..381993)
                     /locus_tag="Smed_3929"
                     /note="PFAM: transposase IS111A/IS1328/IS1533; transposase
                     IS116/IS110/IS902 family protein;
                     KEGG: hne:HNE_2108 ISHne4, transposase"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS116/IS110/IS902 family protein"
                     /protein_id="YP_001312672.1"
                     /db_xref="GI:150376076"
                     /db_xref="InterPro:IPR002525"
                     /db_xref="InterPro:IPR003346"
                     /db_xref="GeneID:5318765"
                     /translation="MIHPDVIGCDIAKAHLDFFDSGLERHFRIDNTPAAISAWLDGLD
                     GRGVHIVFEATGRYDRQLRIALETPELPYSRVNPARARDFAKAIGLLAKTDAIDARLL
                     ARMGQSLPLSTQAPDDPARHVLARLHTRRDQLVAMRQQERTRLHETEGIERDSAESHM
                     AWLDAEVARIEMACRDVLKAEKTLQEQEARLRSIPGIGPVAALTLIAHMPELGNRSAK
                     AIAALAGLAPFNVDSGTSRGKRHIRGGRKRIRDALYMAALTASRMPRAFKSHADQMKE
                     AGKPFKVVIIALARKLLAIANAIIRDKTTFRRTT"
     misc_feature    complement(381562..381978)
                     /locus_tag="Smed_3929"
                     /note="Transposase; Region: DEDD_Tnp_IS110; pfam01548"
                     /db_xref="CDD:216564"
     misc_feature    complement(<381373..381849)
                     /locus_tag="Smed_3929"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG3547"
                     /db_xref="CDD:226077"
     misc_feature    complement(381184..381429)
                     /locus_tag="Smed_3929"
                     /note="Transposase IS116/IS110/IS902 family; Region:
                     Transposase_20; pfam02371"
                     /db_xref="CDD:217002"
     gene            complement(382401..382970)
                     /locus_tag="Smed_3930"
                     /db_xref="GeneID:5318766"
     CDS             complement(382401..382970)
                     /locus_tag="Smed_3930"
                     /EC_number="4.4.1.22"
                     /note="catalyzes the reaction of formaldehyde with
                     glutathione to form S-hydroxymethylglutathione"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde-activating
                     protein"
                     /protein_id="YP_001312673.1"
                     /db_xref="GI:150376077"
                     /db_xref="InterPro:IPR006913"
                     /db_xref="InterPro:IPR014185"
                     /db_xref="GeneID:5318766"
                     /translation="MLKLHPSIDNGFPPASPGFAGGTLKCRCASNPVTVEIGAQTAHN
                     HACGCTKCWKPEGAIFAQIAVVSRDKVNVTSGSEKLQVVDPNATIQRYACRDCGTHMY
                     GRIENTKHPFYGLDFVHTELSNETGWSPPEFAAFVSSIIESGVNPERMPEIRERLKEI
                     GLEPYDALSPPLMDAIATHIAKQTGALPA"
     misc_feature    complement(382404..382970)
                     /locus_tag="Smed_3930"
                     /note="glutathione-dependent formaldehyde-activating
                     enzyme; Provisional; Region: PRK05417"
                     /db_xref="CDD:235451"
     gene            complement(383090..383881)
                     /locus_tag="Smed_3931"
                     /db_xref="GeneID:5318767"
     CDS             complement(383090..383881)
                     /locus_tag="Smed_3931"
                     /note="PFAM: ABC-2 type transporter;
                     KEGG: sme:SMb20185 putative ABC-2 type transport system
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 type transporter"
                     /protein_id="YP_001312674.1"
                     /db_xref="GI:150376078"
                     /db_xref="InterPro:IPR000412"
                     /db_xref="InterPro:IPR013525"
                     /db_xref="InterPro:IPR013526"
                     /db_xref="GeneID:5318767"
                     /translation="MKAWLIALSAVVTRENLRFVRQRGRFLAALVRPLVWLIVFAAGF
                     RAALGVSIIPPYQTYITYEVYILPGLCGMIQLFNGMQSSLALVYDQEMGSMRLLLTSP
                     LPRWWLLFSKLLAGVIVSILQVAVFLGIAALTGITVPPVGYVAVLPALVISGLMLGAF
                     GLLISSTVRQLENFAGVMNFVIFPMFFLSSALYPLWKMAESSPLLRDICALNPFTYAV
                     ELIRFALYGELDLTALVWVGTCFILFMLAALWGYNPARAMLRSKG"
     misc_feature    complement(383126..383881)
                     /locus_tag="Smed_3931"
                     /note="ABC-type multidrug transport system, permease
                     component [Defense mechanisms]; Region: COG0842"
                     /db_xref="CDD:223912"
     misc_feature    complement(383111..383869)
                     /locus_tag="Smed_3931"
                     /note="alcohol ABC transporter, permease protein; Region:
                     phenyl_ABC_PedC; TIGR03861"
                     /db_xref="CDD:163573"
     gene            complement(383878..384606)
                     /locus_tag="Smed_3932"
                     /db_xref="GeneID:5318768"
     CDS             complement(383878..384606)
                     /locus_tag="Smed_3932"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20184 putative ABC transporter ATP-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312675.1"
                     /db_xref="GI:150376079"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318768"
                     /translation="MIGLEVSHVSYSYGKSKALHDVSFSVENGRFCALLGPNGAGKST
                     LFALLTRLLATGEGKIGVAGFDIAREPRAALARIGVVFQQPTLDLDMSVRRNLRYFAG
                     LHGLSGRPAAVAIEAALTQLGMAERADEQVRALNGGHRRRMEIARALIHGPQILLLDE
                     PTVGLDAASRLAITDHVHQLAESGLSVLWATHLVDEIRPTDQVVVLHRGKVLSDGRAG
                     ELAGGQGLAKAFLSMTAEDREIVT"
     misc_feature    complement(383905..384600)
                     /locus_tag="Smed_3932"
                     /note="ABC transporter, ATP-binding subunit, PQQ-dependent
                     alcohol dehydrogenase system; Region: PQQ_ABC_ATP;
                     TIGR03864"
                     /db_xref="CDD:188394"
     misc_feature    complement(383947..384597)
                     /locus_tag="Smed_3932"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    complement(384478..384501)
                     /locus_tag="Smed_3932"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(384031..384033,384127..384132,
                     384358..384360,384475..384483,384487..384492))
                     /locus_tag="Smed_3932"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(384358..384369)
                     /locus_tag="Smed_3932"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(384175..384204)
                     /locus_tag="Smed_3932"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(384127..384144)
                     /locus_tag="Smed_3932"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(384109..384120)
                     /locus_tag="Smed_3932"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(384025..384045)
                     /locus_tag="Smed_3932"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            complement(384593..385240)
                     /locus_tag="Smed_3933"
                     /db_xref="GeneID:5318769"
     CDS             complement(384593..385240)
                     /locus_tag="Smed_3933"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20183 putative ABC transporter ATP-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312676.1"
                     /db_xref="GI:150376080"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318769"
                     /translation="MIKVDVRRKAFGEEEVLRAIRFEMETGETVAILGPSGIGKSTLL
                     RLIVGIDTGFEGKITRPEKIAMVFQEPVLLPWRSVVENLTLVHPQLGTQAALSALERT
                     GIADKAGLFPGQLSLGQQRRLALARAFAGRPELLVMDEPYVSLDPAMAEDMLSLTEAL
                     IAETAPAVILVTHSEAEARRLARRCLRLAGKPATIIEEFAAKPASDGWEGHHDRA"
     misc_feature    complement(384644..385219)
                     /locus_tag="Smed_3933"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    complement(384719..385216)
                     /locus_tag="Smed_3933"
                     /note="putative bacteriocin export ABC transporter,
                     lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608"
                     /db_xref="CDD:188353"
     misc_feature    complement(385118..385141)
                     /locus_tag="Smed_3933"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(384722..384724,384821..384826,
                     385034..385036,385115..385123,385127..385132))
                     /locus_tag="Smed_3933"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(385034..385045)
                     /locus_tag="Smed_3933"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(384869..384898)
                     /locus_tag="Smed_3933"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(384821..384838)
                     /locus_tag="Smed_3933"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(384803..384814)
                     /locus_tag="Smed_3933"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(384716..384736)
                     /locus_tag="Smed_3933"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            complement(385237..386016)
                     /locus_tag="Smed_3934"
                     /db_xref="GeneID:5318515"
     CDS             complement(385237..386016)
                     /locus_tag="Smed_3934"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20182 putative ABC transporter protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001312677.1"
                     /db_xref="GI:150376081"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318515"
                     /translation="MDCSCTLNKTLQHPALVRALSLGLLLLLWIAAAALTADASVLPQ
                     PWALWTPFLQALGSGALPYHLGMTLWRVVCAFVPAMIIGVAVGFLMGRFASVDRWLDP
                     WLVVFLNLPALVLIVLCYIWIGLNETAAITAVVLNKIPNVATLLREGTRALDPNLDSM
                     AAVYRMRPLARLRHVIMPQLAPFIAASARAGIAVIWKIVLVVEFLGRSSGIGFQIHFY
                     FQLFNVAMVLVYALSFIGVMLLVEALFLQPAERRVRRWRTA"
     sig_peptide     complement(385906..386016)
                     /locus_tag="Smed_3934"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.992) with cleavage site probability 0.488 at
                     residue 37"
     misc_feature    complement(385240..385896)
                     /locus_tag="Smed_3934"
                     /note="ABC-type nitrate/sulfonate/bicarbonate transport
                     system, permease component [Inorganic ion transport and
                     metabolism]; Region: TauC; COG0600"
                     /db_xref="CDD:223673"
     misc_feature    complement(385294..385824)
                     /locus_tag="Smed_3934"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(385297..385302,385309..385314,
                     385318..385323,385330..385335,385363..385368,
                     385405..385410,385417..385428,385447..385449,
                     385456..385461,385501..385503,385552..385554,
                     385561..385566,385576..385578,385582..385587,
                     385594..385596,385600..385602,385606..385611,
                     385657..385659,385663..385668,385675..385704,
                     385708..385719,385744..385746,385759..385764,
                     385771..385776))
                     /locus_tag="Smed_3934"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(385411..385428,385657..385701))
                     /locus_tag="Smed_3934"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(385333..385335,385363..385365,
                     385372..385374,385408..385410,385624..385626,
                     385657..385659))
                     /locus_tag="Smed_3934"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(385480..385482,385492..385497,
                     385513..385551))
                     /locus_tag="Smed_3934"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(385991..386974)
                     /locus_tag="Smed_3935"
                     /db_xref="GeneID:5318516"
     CDS             complement(385991..386974)
                     /locus_tag="Smed_3935"
                     /note="KEGG: sme:SMb20181 putative ABC transporter
                     periplasmic solute-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter periplasmic
                     solute-binding protein"
                     /protein_id="YP_001312678.1"
                     /db_xref="GI:150376082"
                     /db_xref="GeneID:5318516"
                     /translation="MKVFEQLAVCLFAACLLALGPTFALAEELPQLRAAMLASGTVNW
                     EISTIKTHEFDRANGFELVVQDYADNGATRVAFEGGEADTMVADWIWVANQRAAGKDY
                     VFIPYSRAVGGLMVKDDSDIKALPDLAGKKIGIAGGPLDKSWLILRAYAKQQHGMDLA
                     AETEQVFGAPPLIFKSALSGETAGTINFWHFLAKMRAKGMHELISVSDAAAALKLDPD
                     TPLLGYVLKGEYAATHPDIVKGLYKASRAAKDLLRSDDEVWGALRDKMNAADDAEFVA
                     LRDGYRAGIPSGKPIDEAAADRFLRLMAELGGEELVGKATSLPNGLFLHLE"
     sig_peptide     complement(386894..386974)
                     /locus_tag="Smed_3935"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.998 at
                     residue 27"
     misc_feature    complement(386237..386809)
                     /locus_tag="Smed_3935"
                     /note="NMT1/THI5 like; Region: NMT1; pfam09084"
                     /db_xref="CDD:220105"
     misc_feature    complement(<386561..>386737)
                     /locus_tag="Smed_3935"
                     /note="Bacterial periplasmic transport systems use
                     membrane-bound complexes and substrate-bound,
                     membrane-associated, periplasmic binding proteins (PBPs)
                     to transport a wide variety of  substrates, such as, amino
                     acids, peptides, sugars, vitamins and inorganic...;
                     Region: PBPb; cl17432"
                     /db_xref="CDD:247986"
     gene            complement(387038..387481)
                     /locus_tag="Smed_3936"
                     /db_xref="GeneID:5318517"
     CDS             complement(387038..387481)
                     /locus_tag="Smed_3936"
                     /note="KEGG: sme:SMb20180 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312679.1"
                     /db_xref="GI:150376083"
                     /db_xref="GeneID:5318517"
                     /translation="MHRSFVAALATLFLAGPAAAAPLCADMGFAGLLAKCNRGEPIEI
                     TLASGKPLGKGAITLQSGAYYEMQITADGSAELAITGAPFFRAIWMNEIVVNGIEVRP
                     MAIDSLEFDEAGTATLSFIAIKPGTYEVRIPETSSDSQKVSISIQ"
     sig_peptide     complement(387419..387481)
                     /locus_tag="Smed_3936"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.985 at
                     residue 21"
     gene            complement(387522..388526)
                     /locus_tag="Smed_3937"
                     /db_xref="GeneID:5318518"
     CDS             complement(387522..388526)
                     /locus_tag="Smed_3937"
                     /note="TIGRFAM: 40-residue YVTN family beta-propeller
                     repeat protein;
                     PFAM: WD-40 repeat protein;
                     KEGG: sme:SMb20179 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="YVTN beta-propeller repeat-containing protein"
                     /protein_id="YP_001312680.1"
                     /db_xref="GI:150376084"
                     /db_xref="InterPro:IPR001680"
                     /db_xref="InterPro:IPR011964"
                     /db_xref="GeneID:5318518"
                     /translation="MLKSAMALLPAVLMPAVLMPAVLMFAGSAEANKVFVSNERGNNV
                     TVLDSQSWKVIATFPAGNRPRGITISPDGKELYVCASDDDTVRVFDPETYKELHTLPS
                     GPDPELFALAPSGNPLYIANEDDNLVTVVDVKTRQVLAEVPVGVEPEGVAVSPDAKTI
                     INTSETTNMAHFIDAATYKIVHNVLVDQRPRYAEFTADGKKLYVSSEIGGTVSVIDVS
                     AAEPKITRKITFEVPGVLPEWLQPVGVKATKDGSRIFVALGPANRVAVIDGETDEVLD
                     YLLVGQRVWQMAFTPGEEFLITTNGNSNDVSIIDVKAEKVIQSVQVGEQPWGVVVAPN
                     "
     sig_peptide     complement(388431..388526)
                     /locus_tag="Smed_3937"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.877 at
                     residue 32"
     misc_feature    complement(387528..388433)
                     /locus_tag="Smed_3937"
                     /note="PQQ-dependent catabolism-associated beta-propeller
                     protein; Region: PQQ_ABC_repeats; TIGR03866"
                     /db_xref="CDD:234377"
     misc_feature    complement(388317..388433)
                     /locus_tag="Smed_3937"
                     /note="40-residue YVTN family beta-propeller repeat;
                     Region: beta_rpt_yvtn; TIGR02276"
                     /db_xref="CDD:213697"
     misc_feature    complement(387603..388334)
                     /locus_tag="Smed_3937"
                     /note="WD40 domain, found in a number of eukaryotic
                     proteins that cover a wide variety of functions including
                     adaptor/regulatory modules in signal transduction,
                     pre-mRNA processing and cytoskeleton assembly; typically
                     contains a GH dipeptide 11-24 residues from...; Region:
                     WD40; cl02567"
                     /db_xref="CDD:243092"
     misc_feature    complement(order(387612..387614,387633..387635,
                     387684..387686,387723..387728,387744..387746,
                     387759..387761,387810..387815,387879..387884,
                     387900..387902,387915..387917,387966..387971,
                     388005..388010,388026..388028,388041..388043,
                     388095..388097,388131..388136,388152..388154,
                     388215..388220,388257..388262,388278..388280,
                     388290..388292))
                     /locus_tag="Smed_3937"
                     /note="structural tetrad; other site"
                     /db_xref="CDD:238121"
     misc_feature    complement(387534..387656)
                     /locus_tag="Smed_3937"
                     /note="40-residue YVTN family beta-propeller repeat;
                     Region: beta_rpt_yvtn; TIGR02276"
                     /db_xref="CDD:213697"
     gene            complement(388528..389817)
                     /locus_tag="Smed_3938"
                     /db_xref="GeneID:5318519"
     CDS             complement(388528..389817)
                     /locus_tag="Smed_3938"
                     /note="KEGG: sme:SMb20178 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312681.1"
                     /db_xref="GI:150376085"
                     /db_xref="GeneID:5318519"
                     /translation="MLEAIPGRVRSGFPSGIAEKRTVRATPRFREKGKCPHLSGLLAL
                     FWVAMLVTSPSQAAEVKTAVLRIDRVVGPPISRLDAPPADLGFAGAMLGNEDNRTTGA
                     FTGMDYTVTTQAVAPEEAGAALDGLKAEGIGLIAVIAEGDILKELSEKAGPGVLLFNA
                     GARDDGLRDADCLANVLHVSPSRSMLSDSIVQFLMWKKWPRILLIHGSHPEDRLLAES
                     YRKSAAKFGAKIVEEREFVDTGGSRRTDTGHVMVQKQIPVFTQEAEPYDVIVAADEAG
                     VFAPYLPYHSWDPRPIAGSAGLRPVSWHPAHEAWGATQFQRRFEKLTGRYMREEDYQA
                     WLAMRVIGEAVTRSGKADPATVRAYALSKDFELAAFKGQKLTFRTWNGQLRQPVLLTE
                     GRVTVSVSPQDGYLHQHSPLDTLGIDAPETACQAFGG"
     sig_peptide     complement(389644..389817)
                     /locus_tag="Smed_3938"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.703) with cleavage site probability 0.700 at
                     residue 58"
     misc_feature    complement(388771..389598)
                     /locus_tag="Smed_3938"
                     /note="Periplasmic binding domain of ATP-binding cassette
                     transporter-like systems that belong to the type I
                     periplasmic binding fold protein superfamily; Region:
                     PBP1_ABC_transporter_LIVBP_like; cd06268"
                     /db_xref="CDD:107263"
     misc_feature    complement(389332..389337)
                     /locus_tag="Smed_3938"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107263"
     gene            389937..390446
                     /locus_tag="Smed_3939"
                     /db_xref="GeneID:5318520"
     CDS             389937..390446
                     /locus_tag="Smed_3939"
                     /note="KEGG: sme:SMb20177 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312682.1"
                     /db_xref="GI:150376086"
                     /db_xref="GeneID:5318520"
                     /translation="MRHILVALILTMWPALACAALDKPLEPGAKVAFLGMTFIDLSTE
                     GTYNGVRADETARLELMESAARDRFVQEGFVMLSTAPVAAELASTVNPADCNGCELHM
                     GERLGADYVLVGEVRKISNLILSVELVLRDVNSGEILRGIAVDIRSNTDDSWLRGIRY
                     ILKNHFFKS"
     sig_peptide     389937..389996
                     /locus_tag="Smed_3939"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.723 at
                     residue 20"
     misc_feature    390018..390437
                     /locus_tag="Smed_3939"
                     /note="Protein of unknown function (DUF2380); Region:
                     DUF3280; pfam11684"
                     /db_xref="CDD:221166"
     gene            complement(390486..391031)
                     /locus_tag="Smed_3940"
                     /db_xref="GeneID:5318521"
     CDS             complement(390486..391031)
                     /locus_tag="Smed_3940"
                     /note="KEGG: sme:SMb20176 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312683.1"
                     /db_xref="GI:150376087"
                     /db_xref="InterPro:IPR001763"
                     /db_xref="GeneID:5318521"
                     /translation="MIRPWLHSLVLLLFAAFPAAAAEEPAGYRESEYRAEVPATLSGA
                     TVVSTEAAHALWKTGQVAFIDVLPRPPKPANLPEGTVWNEKPRLSIPSSLWLPNVGYG
                     MLADVMQDYFRAGLEKATGGDKDRPVLFFCLDGCWMSWNAGKRALEYGYTHVFWYPQG
                     TDGWATAGYPTERIEPEPGGQ"
     sig_peptide     complement(390966..391031)
                     /locus_tag="Smed_3940"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.766 at
                     residue 22"
     misc_feature    complement(390537..390878)
                     /locus_tag="Smed_3940"
                     /note="Rhodanese Homology Domain (RHOD); an alpha beta
                     fold domain found duplicated in the rhodanese protein. The
                     cysteine containing enzymatically active version of the
                     domain is also found in the Cdc25 class of protein
                     phosphatases and a variety of proteins...; Region: RHOD;
                     cd00158"
                     /db_xref="CDD:238089"
     misc_feature    complement(390636..390638)
                     /locus_tag="Smed_3940"
                     /note="active site residue [active]"
                     /db_xref="CDD:238089"
     gene            complement(391028..391885)
                     /locus_tag="Smed_3941"
                     /db_xref="GeneID:5318522"
     CDS             complement(391028..391885)
                     /locus_tag="Smed_3941"
                     /note="SMART: extracellular solute-binding protein family
                     3;
                     KEGG: sme:SMb20175 putative methanol oxidation protein"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312684.1"
                     /db_xref="GI:150376088"
                     /db_xref="InterPro:IPR001638"
                     /db_xref="GeneID:5318522"
                     /translation="MLKRLASATSSLLTAAGIMLPAVAGSQPAAAQTSDLVSKTAFRV
                     CADPANLPMSDREGAGYENKIAELMASKLGLPLEYTWFPMATGFVRKTLQANACDVVI
                     GFAQGDEMVLNTNHYYTSAYVLIAASGGPLAGVTTLADPLLKDKRIGIVAGTPPATHM
                     ARNGLLLKAKGYHLMVDRRYEDPADDMLKDLESGALDAAILWGPIGGPLVKASHPKLK
                     ATPLLAESTPPRLFYRITMGVRQGEKVWERKLNSLIRRNQSEINAILADAGVPLLNDM
                     GTGPLETPK"
     sig_peptide     complement(391790..391885)
                     /locus_tag="Smed_3941"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.666 at
                     residue 32"
     misc_feature    complement(391067..391765)
                     /locus_tag="Smed_3941"
                     /note="quinoprotein dehydrogenase-associated probable ABC
                     transporter substrate-binding protein; Region:
                     ABC_peri_MoxJ_2; TIGR03871"
                     /db_xref="CDD:163583"
     misc_feature    complement(391124..391717)
                     /locus_tag="Smed_3941"
                     /note="Bacterial periplasmic transport systems use
                     membrane-bound complexes and substrate-bound,
                     membrane-associated, periplasmic binding proteins (PBPs)
                     to transport a wide variety of  substrates, such as, amino
                     acids, peptides, sugars, vitamins and inorganic...;
                     Region: PBPb; cd00134"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(391280..391282,391421..391423,
                     391565..391567,391643..391645))
                     /locus_tag="Smed_3941"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(391301..391303,391319..391321,
                     391334..391336))
                     /locus_tag="Smed_3941"
                     /note="membrane-bound complex binding site; other site"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(391178..391189,391202..391207))
                     /locus_tag="Smed_3941"
                     /note="hinge residues; other site"
                     /db_xref="CDD:238078"
     gene            complement(391854..392381)
                     /locus_tag="Smed_3942"
                     /db_xref="GeneID:5318523"
     CDS             complement(391854..392381)
                     /locus_tag="Smed_3942"
                     /note="KEGG: sme:SMb20174 putative cytochrome c protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative cytochrome c protein"
                     /protein_id="YP_001312685.1"
                     /db_xref="GI:150376089"
                     /db_xref="GeneID:5318523"
                     /translation="MTRTRHAVPMILALFTLMAGAAGAEEAPDNITAARDENGRYYTA
                     DDVPTFKVTEDGTVDWLTYSGFRRYHSECHVCHGPEGEGSSYAPALKTSAINMDYYDF
                     VDVVTNGRKKVSAAENSVMPAFGENVNVMCYLDDIYVYLKARGADALPRGRPAKKEAK
                     SDAIKDAEKACLGHE"
     sig_peptide     complement(392307..392381)
                     /locus_tag="Smed_3942"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.980 at
                     residue 25"
     misc_feature    complement(391905..392333)
                     /locus_tag="Smed_3942"
                     /note="Cytochrome c, mono- and diheme variants [Energy
                     production and conversion]; Region: CccA; COG2010"
                     /db_xref="CDD:224921"
     misc_feature    complement(391866..392294)
                     /locus_tag="Smed_3942"
                     /note="c-type cytochrome, methanol metabolism-related;
                     Region: 4cys_cytochr; TIGR03874"
                     /db_xref="CDD:163586"
     gene            complement(392457..394262)
                     /locus_tag="Smed_3943"
                     /db_xref="GeneID:5318524"
     CDS             complement(392457..394262)
                     /locus_tag="Smed_3943"
                     /note="PFAM: Pyrrolo-quinoline quinone;
                     KEGG: sme:SMb20173 putative methanol dehydrogenase
                     protein, large subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="Pyrrolo-quinoline quinone"
                     /protein_id="YP_001312686.1"
                     /db_xref="GI:150376090"
                     /db_xref="InterPro:IPR001479"
                     /db_xref="InterPro:IPR002372"
                     /db_xref="GeneID:5318524"
                     /translation="MKRLLTMLAFMSIGGGAQVAFANDDLQKLIDDPNQWAIQTGDYA
                     NLRYSKLDQINKDNVGKLQVAWTFSTGVLRGHEGSPLVIGDMMYVHTPFPNTVYALDL
                     SKDGQIVWKYEPKQDPNVIPVMCCDTVNRGVAYADNKIFLHQADTTVVALDAKTGKVA
                     WSVKNGDATKGETNTATVMPVKDKVLVGISGGEFGVRGHVTAYSIADGKLLWRAYSMG
                     PDSDTLMNPEKTTHLGKPVGKDSGLTTWEGDQWKIGGGTTWGWYSYDPELNMVYYGTG
                     NPSTWNPTQRPGDNRWSMTVFARDVDTGEAKWVYQMTPHDEWDYDGVNEMILTEQQID
                     GKDRKLLTHFDRNGFGYTMDRVTGELLVAEKYDPTVNWATEVVMDSKSEQFGRPQVVA
                     QYSTEQNGEDTNTTGVCPAALGTKDQQPAAYSPKTELFYVPTNHVCMDYEPFRVSYTA
                     GQPYVGATLSMYPPKDSHGGMGNFIAWDNKEGKIKWSLPEPFSVWSGALATAGDVVFY
                     GTLEGYLKAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGGWAGIGLAA
                     GLTNPTEGLGAVGGYSALSNYTALGGTLTVFKLPE"
     sig_peptide     complement(394194..394262)
                     /locus_tag="Smed_3943"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.997 at
                     residue 23"
     misc_feature    complement(392607..394214)
                     /locus_tag="Smed_3943"
                     /note="PQQ-dependent dehydrogenase, methanol/ethanol
                     family; Region: PQQ_enz_alc_DH; TIGR03075"
                     /db_xref="CDD:234102"
     misc_feature    complement(392466..394157)
                     /locus_tag="Smed_3943"
                     /note="Large subunit of methanol dehydrogenase (moxF);
                     Region: PQQ_MDH; cd10278"
                     /db_xref="CDD:199836"
     misc_feature    complement(order(392469..392471,392475..392477,
                     392682..392684,392691..392699,392706..392708,
                     392712..392714,392805..392807,392814..392822,
                     392829..392831,392835..392837,393177..393179,
                     393186..393194,393201..393203,393207..393209,
                     393339..393341,393348..393356,393363..393365,
                     393369..393371,393627..393629,393636..393644,
                     393651..393653,393657..393659,393780..393782,
                     393789..393797,393804..393806,393810..393812,
                     393933..393935,393942..393950,393960..393962,
                     393966..393968,394065..394067,394074..394082))
                     /locus_tag="Smed_3943"
                     /note="Trp docking motif [polypeptide binding]; other
                     site"
                     /db_xref="CDD:199836"
     misc_feature    complement(order(392490..392498,392601..392603,
                     392667..392678,392721..392723,393924..393926,
                     393930..393932,393939..393947,393969..393971,
                     394044..394046,394050..394073))
                     /locus_tag="Smed_3943"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:199836"
     misc_feature    complement(order(392586..392588,392778..392780,
                     393012..393014,393225..393227,393306..393308,
                     393420..393422,393432..393434,393486..393488,
                     393492..393494,393684..393686,393690..393695,
                     393738..393740,393870..393872,393876..393878,
                     393885..393890,394032..394034))
                     /locus_tag="Smed_3943"
                     /note="active site"
                     /db_xref="CDD:199836"
     misc_feature    complement(order(392916..392921,392928..392930,
                     393312..393314,393318..393320,393390..393392,
                     393396..393404,393408..393416,393504..393509,
                     393522..393524,393528..393533,393624..393626,
                     393642..393644,393672..393680,393762..393785))
                     /locus_tag="Smed_3943"
                     /note="small subunit binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:199836"
     gene            complement(394439..394849)
                     /locus_tag="Smed_3944"
                     /db_xref="GeneID:5318052"
     CDS             complement(394439..394849)
                     /locus_tag="Smed_3944"
                     /note="PFAM: cytochrome c class I;
                     KEGG: sme:SMb20172 putative cytochrome c protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c class I"
                     /protein_id="YP_001312687.1"
                     /db_xref="GI:150376091"
                     /db_xref="InterPro:IPR002327"
                     /db_xref="InterPro:IPR003088"
                     /db_xref="InterPro:IPR009056"
                     /db_xref="GeneID:5318052"
                     /translation="MASRLGSVLTAAVLIGGILGAAAPALALDPAAGDPAAGAKVFRK
                     CQACHTVGPDAKSKTGPLLNGIIGRSAGKVEGYAYSPAIEKAAEAGLTWTPEKIAEFL
                     TSPKGFLPGTKMTFAGLRKDQERADIIAYLATFP"
     sig_peptide     complement(394766..394849)
                     /locus_tag="Smed_3944"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.990 at
                     residue 28"
     misc_feature    complement(394442..>394732)
                     /locus_tag="Smed_3944"
                     /note="Cytochrome c2 [Energy production and conversion];
                     Region: COG3474"
                     /db_xref="CDD:226005"
     gene            complement(394863..395693)
                     /locus_tag="Smed_3945"
                     /db_xref="GeneID:5318053"
     CDS             complement(394863..395693)
                     /locus_tag="Smed_3945"
                     /EC_number="3.1.2.12"
                     /note="TIGRFAM: S-formylglutathione hydrolase;
                     PFAM: putative esterase;
                     KEGG: sme:SMb20171 putative S-formylglutathione hydrolase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="YP_001312688.1"
                     /db_xref="GI:150376092"
                     /db_xref="InterPro:IPR000801"
                     /db_xref="InterPro:IPR014186"
                     /db_xref="GeneID:5318053"
                     /translation="MELVTQSQCFGGTQSVYRHASEVCGVEMTFGLYLPPQARKRSVP
                     LLWYLSGLTCTHENAMIKAGLQRHAAEQGLALIFPDTSPRGDGVADDEAYDLGQGAGF
                     YVNATQKPWSPHYRMYDYIVTELPALLQAQLPVNGVNGITGHSMGGHGALTIAFRNPK
                     LFRSVSAFAPIVNPTRSDWGRKQFSAYLGDDEADWGSYDACLLLSELGWHGDILIDQG
                     AADQFLTELQPEAMARLLAERRQAGVVRLQAGYDHSYYFVASFGEDHVRWHAERLNAA
                     "
     misc_feature    complement(394875..395690)
                     /locus_tag="Smed_3945"
                     /note="S-formylglutathione hydrolase; Region:
                     fghA_ester_D; TIGR02821"
                     /db_xref="CDD:131868"
     misc_feature    complement(394872..395684)
                     /locus_tag="Smed_3945"
                     /note="S-formylglutathione hydrolase; Region: PLN02442"
                     /db_xref="CDD:178061"
     gene            complement(395702..396829)
                     /locus_tag="Smed_3946"
                     /db_xref="GeneID:5318054"
     CDS             complement(395702..396829)
                     /locus_tag="Smed_3946"
                     /note="TIGRFAM: Alcohol dehydrogenase class
                     III/S-(hydroxymethyl)glutathione dehydrogenase;
                     PFAM: Alcohol dehydrogenase zinc-binding domain protein;
                     Alcohol dehydrogenase GroES domain protein;
                     KEGG: sme:SMb20170 probable glutathione-dependent
                     formaldehyde dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase"
                     /protein_id="YP_001312689.1"
                     /db_xref="GI:150376093"
                     /db_xref="InterPro:IPR002328"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR014183"
                     /db_xref="GeneID:5318054"
                     /translation="MRTRAALAVEAGKPLVVTEVELEGPRAGEVLVEVKATGICHTDD
                     FTLSGADPEGLFPAILGHEGAGIVVDVGPGVTSVRKGDHVIPLYTPECRSCPSCLSRK
                     TNLCTAIRATQGQGLMPDGTSRFSIGGDKIHHYMGCSTFSNFTVLPEIAVAKVNPDAP
                     FDKICYIGCGVTTGIGAVINTARVEIGATAIVFGLGGIGLNVIQGLRLAGADMIIGVD
                     LNNDKKPWGEKFGMTHFVNPKEVGEDIVPYLVNLTKRGADQIGGADYTFDCTGNTRVM
                     RQALEASHRGWGKSVIIGVAGAGQEISTRPFQLVTGRTWMGTAFGGARGRTDVPKIVD
                     WYMEGKIEIDPMITHTMPLEDINKGFELMHSGESIRSVVLY"
     misc_feature    complement(395705..396829)
                     /locus_tag="Smed_3946"
                     /note="Zn-dependent alcohol dehydrogenases, class III
                     [Energy production and conversion]; Region: AdhC; COG1062"
                     /db_xref="CDD:223990"
     misc_feature    complement(395711..396829)
                     /locus_tag="Smed_3946"
                     /note="class III alcohol dehydrogenases; Region:
                     alcohol_DH_class_III; cd08300"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(395873..395875,395945..395947,
                     396323..396325,396563..396568,396644..396646,
                     396671..396679,396704..396706,396710..396712))
                     /locus_tag="Smed_3946"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(396323..396325,396641..396646,
                     396710..396712))
                     /locus_tag="Smed_3946"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(395720..395722,395870..395878,
                     395948..395953,396005..396010,396020..396025,
                     396161..396163,396173..396178,396236..396250,
                     396311..396313,396323..396325,396704..396709))
                     /locus_tag="Smed_3946"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(396512..396514,396536..396538,
                     396545..396547,396554..396556))
                     /locus_tag="Smed_3946"
                     /note="structural Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(395873..395890,395897..395905,
                     395912..395935,395942..395944,395969..395980,
                     395999..396004,396035..396037,396068..396070,
                     396509..396511,396515..396517,396521..396526,
                     396530..396532,396539..396544))
                     /locus_tag="Smed_3946"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:176260"
     gene            397000..397638
                     /locus_tag="Smed_3947"
                     /db_xref="GeneID:5318055"
     CDS             397000..397638
                     /locus_tag="Smed_3947"
                     /note="KEGG: sme:SMb20169 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312690.1"
                     /db_xref="GI:150376094"
                     /db_xref="GeneID:5318055"
                     /translation="MRVACHAFGPMRRLAFGLTVGLALGLTQAPGNSVAMDFSDPDWP
                     CIQRKVEKLSASLMWPAPVTTAPLSAEATELVEMLSLRRVSLEEADAHVRAFVERAKV
                     DGNVLGNVFYGVFENIAETRQRLITGIGRYSRSQIALSSRIDSARVEMAKLSKVESPD
                     FDRIDKLEEQIDWDERIYRDRSQALTYVCETPVLLEKRAYAIAQILLKHMPD"
     sig_peptide     397000..397107
                     /locus_tag="Smed_3947"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.752) with cleavage site probability 0.733 at
                     residue 36"
     gene            complement(397704..398762)
                     /locus_tag="Smed_3948"
                     /db_xref="GeneID:5318056"
     CDS             complement(397704..398762)
                     /locus_tag="Smed_3948"
                     /note="PFAM: beta-lactamase domain protein;
                     KEGG: sme:SMb20168 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase domain-containing protein"
                     /protein_id="YP_001312691.1"
                     /db_xref="GI:150376095"
                     /db_xref="InterPro:IPR001279"
                     /db_xref="GeneID:5318056"
                     /translation="MFEAFVTMCILAAAVPDAPPRETCRVALLPGFGAETKAGCEQAL
                     HSVTRRPGNWAEKAPFCAPRPKSVLSFSEAAPGVFLHRGRVAEPDAENGGDVSNFGFV
                     VGSRSIAVIDSGGARKLGEEIYLAIRERSRLPISNLILTHMHPDHVFGAEALREAGAV
                     VLGQADLPRALADRVEDYRASYARRLGETAFLGSRIIAPDRTAAQQEAIDLGGRVLEL
                     RTWPTAHTSTDLTIYDPTSGILFAGDLLFDTHMPALDGSLRGWLAVLSEMKGLGARKV
                     VPGHGGPLLDWPQAAEPLERYLRVLESDTKKALDDGLALGDASETVGQSESARWSLFD
                     LLNPQNATAAYTEMEWDP"
     misc_feature    complement(397923..398462)
                     /locus_tag="Smed_3948"
                     /note="Metallo-beta-lactamase superfamily; Region:
                     Lactamase_B; smart00849"
                     /db_xref="CDD:214854"
     gene            398915..399727
                     /locus_tag="Smed_3949"
                     /db_xref="GeneID:5318057"
     CDS             398915..399727
                     /locus_tag="Smed_3949"
                     /note="PFAM: Sulphur oxidation protein SoxZ;
                     KEGG: sme:SMb20167 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur oxidation protein SoxZ"
                     /protein_id="YP_001312692.1"
                     /db_xref="GI:150376096"
                     /db_xref="InterPro:IPR002035"
                     /db_xref="InterPro:IPR014880"
                     /db_xref="GeneID:5318057"
                     /translation="MKLILALIPVMLTANLALAEPEKPDNPLADGTTWHDLKGDIVGE
                     AAILDGTALFSVAAPYRANDAATVPITIEQTDAAAGPIKSLKLVIDENPAPVAAEIRF
                     GPTMAPLKFETRVRVNQYSNIRAIAETPQGIFMNGRFVKASGGCSAPATKDPVAALKG
                     MGEMRLKLFGGEGKVQKPRREAQIMIRHPNYSGLQRDQITQLFVGAKFISELVVKQGD
                     ELLFALDGGISISENPVFRFSYTDNGAPDFTVHAVDTDGNVFDRVLPKTPPA"
     misc_feature    398915..399358
                     /locus_tag="Smed_3949"
                     /note="Predicted secreted protein [Function unknown];
                     Region: COG5501"
                     /db_xref="CDD:227788"
     sig_peptide     398915..398974
                     /locus_tag="Smed_3949"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.998 at
                     residue 20"
     misc_feature    399020..399352
                     /locus_tag="Smed_3949"
                     /note="Sulfur oxidation protein SoxY; Region: SoxY;
                     pfam13501"
                     /db_xref="CDD:222179"
     misc_feature    399452..399694
                     /locus_tag="Smed_3949"
                     /note="Sulphur oxidation protein SoxZ; Region: SoxZ;
                     pfam08770"
                     /db_xref="CDD:220011"
     gene            complement(399820..400173)
                     /locus_tag="Smed_3950"
                     /db_xref="GeneID:5318058"
     CDS             complement(399820..400173)
                     /locus_tag="Smed_3950"
                     /note="KEGG: sme:SMb20166 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312693.1"
                     /db_xref="GI:150376097"
                     /db_xref="GeneID:5318058"
                     /translation="MMRAALSALAIALTAVPAGGQSMSERLNDYPTEVRADYVFGCMA
                     ANGQSREVLSKCACSIDVIASILPYDKYVQAETVLSLQQGSGEQLAMFKSAVVPRTMV
                     ADLRRAQAEAEMLCF"
     sig_peptide     complement(400111..400173)
                     /locus_tag="Smed_3950"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.926 at
                     residue 21"
     gene            complement(400170..400934)
                     /locus_tag="Smed_3951"
                     /db_xref="GeneID:5318059"
     CDS             complement(400170..400934)
                     /locus_tag="Smed_3951"
                     /note="KEGG: sme:SMb20165 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312694.1"
                     /db_xref="GI:150376098"
                     /db_xref="GeneID:5318059"
                     /translation="MTLPEPLLGSVSLNGSFISDGRSAMRIFFLIALILLGPAHGSAA
                     AAETYELLFHSAALKGLEAEKAGNGDPQGGLVYDKVVSGVDSGERSGRFAVGLKVQAG
                     DNVSMTLYQGSQSRGLGNYPRSVGNPLIMYFLESVLSDLAAQSGGSPFYMRNRIKEAL
                     LRDAQIEPVTLRYNDREIAAREVTIRPFEHDKAREKMGRVADLSLAVTVSEDVPGWYF
                     SLVATIPSAADSSGAGYSHAITLRASGSNASGEDQP"
     sig_peptide     complement(400797..400934)
                     /locus_tag="Smed_3951"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.782) with cleavage site probability 0.574 at
                     residue 46"
     gene            complement(400959..403202)
                     /locus_tag="Smed_3952"
                     /db_xref="GeneID:5318060"
     CDS             complement(400959..403202)
                     /locus_tag="Smed_3952"
                     /note="PFAM: response regulator receiver; ATP-binding
                     region ATPase domain protein; histidine kinase A domain
                     protein;
                     KEGG: sme:SMb20164 putative sensor histidine kinase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="YP_001312695.1"
                     /db_xref="GI:150376099"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="GeneID:5318060"
                     /translation="MIDPNEAYEIQIAKQAKIIEALVNRAERGHEVGGTAYSLFESAI
                     ALQAEVWEKTKDLEKALDTLDRASSELEVAYQTQERIQRNLADAMVAMEDGFALFSEE
                     RLQACNAQFRQLLPDVEPLIKPGLGFDDYLAAVNASKYLNRDENGVSGRPHPVAKEQG
                     SGQRFSSFVMVLRNDRWFQISYRQTSSGNITVLQTEITDIVRENRREKNRLIDQQSHL
                     LQAAFDHMSLGICTFSSRGELLVRNERFGELLGVPLSLLKKRSPFQRIVEHVERHEIL
                     DREGRRSRVSGWFKAVRRGEAVQERFRRRDGMGLDIRIHSLPDDGFIVSIMDVTAETE
                     ASALLEQRVQERTAELTEANRLLQIHADEQTKIEAALRHAKEAAEAAHTSKTRFLAAA
                     SHDLLQPINAAKLYLSMLTDRMGQPGVEEVVSRLKRSFTSIESLLQALLDISRLDSSG
                     AEFNVTSFNLGSLLQGVAEDLAPLATERAIELRIVPSTRWVSSDQRYLMRCVQNLVVN
                     AIQYTERGRVLVGCRLKGDAVRIEVWDTGVGISEEDRARIFKEFTRASGAAKGPGMGL
                     GLSIVERACRHLGHPIGLASQPGRGSVFSIEVPLAPPGRASVSEEPRMEPMLEGSLDL
                     IVMIVENDADELHAMTQVLESWGASVLAAGSTADAAALMQEIGTAPDILLVDYQLNDD
                     DNGIETIRTLRALAGAEIPAIIISANRQRQFLQLCTEMSFAVLTKPVQLVRLRALIDW
                     KTRARVA"
     misc_feature    complement(402597..402929)
                     /locus_tag="Smed_3952"
                     /note="PAS fold; Region: PAS_7; pfam12860"
                     /db_xref="CDD:221813"
     misc_feature    complement(401415..402569)
                     /locus_tag="Smed_3952"
                     /note="phosphate regulon sensor kinase PhoR; Region:
                     phoR_proteo; TIGR02966"
                     /db_xref="CDD:234074"
     misc_feature    complement(401868..402053)
                     /locus_tag="Smed_3952"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    complement(order(401883..401885,401895..401897,
                     401904..401906,401916..401918,401925..401927,
                     401937..401939,401985..401987,401994..401996,
                     402006..402008,402015..402017,402027..402029,
                     402039..402041))
                     /locus_tag="Smed_3952"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    complement(402021..402023)
                     /locus_tag="Smed_3952"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    complement(401409..401711)
                     /locus_tag="Smed_3952"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(401421..401423,401427..401432,
                     401445..401447,401451..401453,401499..401510,
                     401583..401588,401592..401594,401598..401600,
                     401604..401606,401670..401672,401679..401681,
                     401691..401693))
                     /locus_tag="Smed_3952"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(401679..401681)
                     /locus_tag="Smed_3952"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(401502..401504,401508..401510,
                     401586..401588,401592..401594))
                     /locus_tag="Smed_3952"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(400986..401327)
                     /locus_tag="Smed_3952"
                     /note="Response regulator receiver domain; Region:
                     Response_reg; pfam00072"
                     /db_xref="CDD:200976"
     misc_feature    complement(400989..401324)
                     /locus_tag="Smed_3952"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(401019..401024,401031..401033,
                     401085..401087,401148..401150,401175..401177,
                     401310..401315))
                     /locus_tag="Smed_3952"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(401175..401177)
                     /locus_tag="Smed_3952"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(401148..401150,401154..401159,
                     401163..401168))
                     /locus_tag="Smed_3952"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(401016..401024)
                     /locus_tag="Smed_3952"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     gene            complement(403199..404368)
                     /locus_tag="Smed_3953"
                     /db_xref="GeneID:5318061"
     CDS             complement(403199..404368)
                     /locus_tag="Smed_3953"
                     /note="PFAM: domain of unknown function DUF1745;
                     KEGG: sme:SMb20163 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312696.1"
                     /db_xref="GI:150376100"
                     /db_xref="InterPro:IPR013702"
                     /db_xref="GeneID:5318061"
                     /translation="MTAVDDLERKPAEAVRLATSRAEDAFTALADIRRQLATARPSFI
                     FLFVPNRLQTDDLAAALRKSLPNTVVFGCTTAGQITPRGYENDALLAVAFQRHHFRVA
                     SILFQPISPVSIADVVSQTERLASQFRVTPGRKRLALIFADGLSKQEDVLVAALEAGL
                     KDIPVFGGSAGDGLRFQRTQVLRNGEFHSNAALLLLLETDLEFSGLGFDHFQPTDKRM
                     VVTRAVPEERLVLEINGSPAAEEYARLVKVPVDELSPMVFAENPVLVRNGNLYHVRAI
                     QQIHGEHGLTFLSAIDDGLLLRLGRGKEIIRTLETGLAVNGHDGEAPDFILGFDCYLR
                     KLEIERKGLDSEVSQQLRQNRVVGFNTYGEQHLGVHVNQTFVGVAFFRPKEGAPL"
     misc_feature    complement(403229..404338)
                     /locus_tag="Smed_3953"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3287"
                     /db_xref="CDD:225825"
     misc_feature    complement(403658..404251)
                     /locus_tag="Smed_3953"
                     /note="FIST N domain; Region: FIST; pfam08495"
                     /db_xref="CDD:219867"
     misc_feature    complement(403271..403657)
                     /locus_tag="Smed_3953"
                     /note="FIST C domain; Region: FIST_C; pfam10442"
                     /db_xref="CDD:220757"
     gene            complement(404412..405101)
                     /locus_tag="Smed_3954"
                     /db_xref="GeneID:5318188"
     CDS             complement(404412..405101)
                     /locus_tag="Smed_3954"
                     /note="PFAM: regulatory protein LuxR; response regulator
                     receiver; Sigma-70 region 4 type 2;
                     KEGG: sme:SMb20162 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="two component LuxR family transcriptional
                     regulator"
                     /protein_id="YP_001312697.1"
                     /db_xref="GI:150376101"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR013249"
                     /db_xref="GeneID:5318188"
                     /translation="MPRTALPVHSLSIKSALVIDDHPLYCDALAATMESTFNTRRIRT
                     ATSLSEALQQLRLRFSPDLIMLDLNLPDASGLSGFLKIKEKMPDIPVIVISAFTSHDV
                     VQSVMAAGAAGFIPKDIDRHNFQEAMQDIWNGKTYVPPGYAVQARATAADQSAETISR
                     KIAHLSQQQTRILSLICEGMPNKLIAYEMQLAEATVKAHITALLRRLGVHNRTQAAML
                     VREVSIRHSLQ"
     misc_feature    complement(404439..405053)
                     /locus_tag="Smed_3954"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    complement(404709..405053)
                     /locus_tag="Smed_3954"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(404748..404753,404760..404762,
                     404817..404819,404877..404879,404901..404903,
                     405039..405044))
                     /locus_tag="Smed_3954"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(404901..404903)
                     /locus_tag="Smed_3954"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(404877..404885,404889..404894))
                     /locus_tag="Smed_3954"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(404745..404753)
                     /locus_tag="Smed_3954"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(404439..404609)
                     /locus_tag="Smed_3954"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(404466..404468,404499..404513,
                     404517..404522,404526..404531,404553..404561,
                     404598..404606))
                     /locus_tag="Smed_3954"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(404439..404444,404451..404453,
                     404460..404468,404559..404561,404565..404567,
                     404571..404573))
                     /locus_tag="Smed_3954"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(405341..405550)
                     /locus_tag="Smed_3955"
                     /db_xref="GeneID:5318189"
     CDS             complement(405341..405550)
                     /locus_tag="Smed_3955"
                     /note="KEGG: rpe:RPE_0841 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312698.1"
                     /db_xref="GI:150376102"
                     /db_xref="GeneID:5318189"
                     /translation="MDPVTLVLTVCLASAPEKCREETLRFQDLRSLNQCMFQSAVYIA
                     EWSEQHPALRVKKWRCRLADGTQPV"
     gene            405562..405699
                     /locus_tag="Smed_3956"
                     /pseudo
                     /db_xref="GeneID:5318190"
     gene            complement(405893..406240)
                     /locus_tag="Smed_3957"
                     /db_xref="GeneID:5318191"
     CDS             complement(405893..406240)
                     /locus_tag="Smed_3957"
                     /note="KEGG: mlo:msl0999 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RpiR family transcriptional regulator"
                     /protein_id="YP_001312699.1"
                     /db_xref="GI:150376103"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="InterPro:IPR000281"
                     /db_xref="GeneID:5318191"
                     /translation="MTTQPPRHASGTKDGGGSKAQARRESRTPPSNLYELKSMIAKRE
                     VVFPGELERVMRAVLDQPEFIAFSTATSIAGKCGVSRTTVVRLASHLGFGKFRDFKNL
                     FREHFKEAANAGR"
     misc_feature    complement(<405905..406138)
                     /locus_tag="Smed_3957"
                     /note="Transcriptional regulators [Transcription]; Region:
                     RpiR; COG1737"
                     /db_xref="CDD:224651"
     misc_feature    complement(405941..>406084)
                     /locus_tag="Smed_3957"
                     /note="Helix-turn-helix domain, rpiR family; Region:
                     HTH_6; pfam01418"
                     /db_xref="CDD:201784"
     gene            complement(406237..406857)
                     /locus_tag="Smed_3958"
                     /db_xref="GeneID:5318192"
     CDS             complement(406237..406857)
                     /locus_tag="Smed_3958"
                     /note="PFAM: Dual specificity protein phosphatase;
                     KEGG: sme:SMb20160 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Dual specificity protein phosphatase"
                     /protein_id="YP_001312700.1"
                     /db_xref="GI:150376104"
                     /db_xref="InterPro:IPR000340"
                     /db_xref="GeneID:5318192"
                     /translation="MQQLDPDPQSIAAELPKLSLIYEKHPLYQVDLFISGKEGASDLE
                     LLRQNGVTTVVNCAVNLDFNYVRRAGLVSDHEGSAYGPGEIRYYKIGLIDGSGNPDTQ
                     MVAAYFILRAALEQVLPEKPSYPRRERGNVLVNCRGGRSRSVIVMALFLHLTLPSQFT
                     TLDAAIAHIREHRRLSRAEWYKAPKPVLIEAAARAADWIRLIEGVR"
     misc_feature    complement(406336..406764)
                     /locus_tag="Smed_3958"
                     /note="Protein tyrosine phosphatases (PTP) catalyze the
                     dephosphorylation of phosphotyrosine peptides; they
                     regulate phosphotyrosine levels in signal transduction
                     pathways. The depth of the active site cleft renders the
                     enzyme specific for phosphorylated Tyr; Region: PTPc;
                     cl00053"
                     /db_xref="CDD:241574"
     misc_feature    complement(order(406429..406434,406441..406443,
                     406450..406455,406576..406578))
                     /locus_tag="Smed_3958"
                     /note="active site"
                     /db_xref="CDD:238073"
     misc_feature    complement(order(406450..406452,406576..406578))
                     /locus_tag="Smed_3958"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:238073"
     gene            complement(406914..407870)
                     /locus_tag="Smed_3959"
                     /db_xref="GeneID:5318193"
     CDS             complement(406914..407870)
                     /locus_tag="Smed_3959"
                     /EC_number="3.1.3.25"
                     /note="PFAM: inositol monophosphatase;
                     KEGG: sme:SMb20159 putative inositol monophosphatase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-phosphate phosphatase"
                     /protein_id="YP_001312701.1"
                     /db_xref="GI:150376105"
                     /db_xref="InterPro:IPR000760"
                     /db_xref="GeneID:5318193"
                     /translation="MIQAGAGPRAGLSPTDRFQQTGYSMQPKPSSGSHIADPDSAALS
                     GRLAEIARGAALAVRMPLLEAFRSEMAVDYKADLHDIVTVHDRRAEAIIRAYILEHEP
                     NSAIMGEEGGQTGDGEFQWYVDPIDGTANFARGIAFWCVSVAVVREGAVLAGAVYDPV
                     ADLMFSADLESAELNGNALASRAADNEKHATLITGYPVARDFRVDGREAALANFGILV
                     ETFSTLRRPGSAALSIAHVAAGWADAAAGFGVNAWDVAAATLILKNAGGRYEPLTLGK
                     VAADGPDFMCPGYIATGRGADYPTLERVARSISTSRIAKTGQ"
     misc_feature    complement(406953..407732)
                     /locus_tag="Smed_3959"
                     /note="Archaeal fructose-1,6-bisphosphatase and related
                     enzymes of inositol monophosphatase family [Carbohydrate
                     transport and metabolism]; Region: SuhB; COG0483"
                     /db_xref="CDD:223559"
     misc_feature    complement(406995..407726)
                     /locus_tag="Smed_3959"
                     /note="Inositol-monophosphatase-like domains. This family
                     of phosphatases is dependent on bivalent metal ions such
                     as Mg++, and many members are inhibited by Li+ (which is
                     thought to displace a bivalent ion in the active site).
                     Substrates include fructose-1; Region: IMPase_like;
                     cd01637"
                     /db_xref="CDD:238815"
     misc_feature    complement(order(407109..407114,407484..407501,
                     407541..407546,407613..407615))
                     /locus_tag="Smed_3959"
                     /note="active site"
                     /db_xref="CDD:238815"
     gene            complement(407867..408994)
                     /locus_tag="Smed_3960"
                     /db_xref="GeneID:5318194"
     CDS             complement(407867..408994)
                     /locus_tag="Smed_3960"
                     /note="KEGG: sme:SMb20158 hypothetical ABC transporter
                     periplasmic solute-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter periplasmic solute-binding
                     protein"
                     /protein_id="YP_001312702.1"
                     /db_xref="GI:150376106"
                     /db_xref="GeneID:5318194"
                     /translation="MSRNSKVGPATIATVGLMAGLIGAKAVAAGGFDLNRLIEAAKNE
                     KPITIYDSTGKIVEMAENFNAKYGLKATGMKVSANSQLEMIIREAQANNVQGDVVLIT
                     DAPAALAQLLPDEFVESYLPEDMAAKIPPEFQKPLAISTNANVWAYNTEAYDKCPVSN
                     IWELTEPQWRGKVALVDPLTKSTYTDWFNQMEAHGDDKVAAAYKAHFGQELRSEEKSA
                     SAAWVKAMAQNAPLATDGDDPVAEAVGAPGQKEPFFGLLSSAKFRDNEAKGYKLGICK
                     ELEPWVGWTYVKLGLIASKTSSPNAAKLFIHYILTEEGIAPQMKDGKLPTNTDIRMPA
                     DEPSGLMAVSDRLFGYDAATGLSDFDRREEWQDLWRTNYSK"
     sig_peptide     complement(408908..408994)
                     /locus_tag="Smed_3960"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.997) with cleavage site probability 0.897 at
                     residue 29"
     misc_feature    complement(408029..408856)
                     /locus_tag="Smed_3960"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_11; pfam13531"
                     /db_xref="CDD:222203"
     misc_feature    complement(407870..408820)
                     /locus_tag="Smed_3960"
                     /note="ABC-type Fe3+ transport system, periplasmic
                     component [Inorganic ion transport and metabolism];
                     Region: AfuA; COG1840"
                     /db_xref="CDD:224753"
     gene            complement(409077..410201)
                     /locus_tag="Smed_3961"
                     /db_xref="GeneID:5318195"
     CDS             complement(409077..410201)
                     /locus_tag="Smed_3961"
                     /note="KEGG: sme:SMb20157 hypothetical ABC transporter
                     periplasmic solute-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter periplasmic solute-binding
                     protein"
                     /protein_id="YP_001312703.1"
                     /db_xref="GI:150376107"
                     /db_xref="GeneID:5318195"
                     /translation="MKRNARSGRYLFLGTAMLCVLGSGAWAEEPFDMDALVEAARKEK
                     PITVYDSTGKIVEMAKNFADKYDVGAEGSKVKASAQLEMIIREARANNIQGDVSIISD
                     APAAMAQLIPQGFAESWVPPDFAGNIAAEHQDPLTVVTSANVWAYNTELFDKCPVTNI
                     WQLTEPKWKGKVAMQDPLGKASYVDWFNQMAKHGDEKLAAAYKDLYGKELQTEETSAT
                     AAWVKALAANAPLLTDADAAAADAVGAPGQSEPFMGLMSSAKFRDNAEKGMKLGLCKD
                     LKPWVGWLYPGVGLITKGTDSPNAARLFIHYVMTAEGIAPQAVDGKMSTNREVALPED
                     EPSGIAAVLDQLLPYSMATSLDDWDARETWQDFWRVNYQK"
     sig_peptide     complement(410118..410201)
                     /locus_tag="Smed_3961"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 28"
     misc_feature    complement(409257..410066)
                     /locus_tag="Smed_3961"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_11; pfam13531"
                     /db_xref="CDD:222203"
     misc_feature    complement(409080..410030)
                     /locus_tag="Smed_3961"
                     /note="ABC-type Fe3+ transport system, periplasmic
                     component [Inorganic ion transport and metabolism];
                     Region: AfuA; COG1840"
                     /db_xref="CDD:224753"
     gene            complement(410252..411388)
                     /locus_tag="Smed_3962"
                     /db_xref="GeneID:5318196"
     CDS             complement(410252..411388)
                     /locus_tag="Smed_3962"
                     /note="PFAM: ABC transporter related; Transport-associated
                     OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20156 putative ABC transporter ATP-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312704.1"
                     /db_xref="GI:150376108"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5318196"
                     /translation="MPTINLRGAQKNYGVNSANAVSDLDLEIRDGEFMCLLGPSGCGK
                     TTTLRMIAGLENLSGGEIRVGDRVVDCVSGGVFVPPEKREMGLVFQSYALWPHLTIER
                     NTDFGLRLRKLPKAEREERVERVMQALDIAKYRDRYPSQLSGGQQQRVALARMLAINP
                     GVLLLDEPLSNLDARLRLEMRAELKRLHKEFKTTIVFVTHDQWEAMTLATTIAVMNEG
                     TLQQIGTPNDIYDRPANRFVAEFVGSPPINILDFGDPGTSDVTDKAEAYLAAHLPGLR
                     SIGSVGIRPEAIGYAARTEDVPEGSFSGETTVTGVLPTGGNWILELRTDNHTLFLTTH
                     VPPRVEQGARVLFFAPPEALHVFDADGRRIAEADDRLRSTATYN"
     misc_feature    complement(410309..411388)
                     /locus_tag="Smed_3962"
                     /note="ABC-type sugar transport systems, ATPase components
                     [Carbohydrate transport and metabolism]; Region: MalK;
                     COG3839"
                     /db_xref="CDD:226359"
     misc_feature    complement(410660..411379)
                     /locus_tag="Smed_3962"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    complement(411254..411277)
                     /locus_tag="Smed_3962"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(410789..410791,410888..410893,
                     411119..411121,411251..411259,411263..411268))
                     /locus_tag="Smed_3962"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(411119..411130)
                     /locus_tag="Smed_3962"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(410936..410965)
                     /locus_tag="Smed_3962"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(410888..410905)
                     /locus_tag="Smed_3962"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(410870..410881)
                     /locus_tag="Smed_3962"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(410783..410803)
                     /locus_tag="Smed_3962"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(410318..410548)
                     /locus_tag="Smed_3962"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            complement(411388..413238)
                     /locus_tag="Smed_3963"
                     /db_xref="GeneID:5318197"
     CDS             complement(411388..413238)
                     /locus_tag="Smed_3963"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20155 putative ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312705.1"
                     /db_xref="GI:150376109"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318197"
                     /translation="MALLSESAKAVAAANGPAAPTAWQAWRYRLKVALREPTTLIGVL
                     TALLFTYLIVVPIISIVLDAARVQFGHERRLSKDVGEFTLYYLDRVLFSPVSADLFWR
                     PLLNTLSVAMGAILLSLVIGTVLAWLISRTDMFGRRWFATALIVPYMLPAWTFALAWT
                     TLFKNRTVGGQPGWLEAVGLTPPDWLAYGRFPITIILALHYTPFVILLFGSALRRFDS
                     QLEDSARILGARHHQVALQIILPLMRPALLSSMVLIFAKCLGEFGVPYVLGLPVKFEV
                     LSTSLFRSIASRQTGVAGVIAGSIMLIGIITLLIDARLVREARRFVTIGSKGSMDRQS
                     RLGRMRLPAAGFAATVFLMSVGLPLLTLFLSTIMKLPARFTLDNFTLDYWIGRDLDTV
                     ALKTGILLSPDLWAAAKNTLTIVGLASVTSGILGLLVGYVVIRTPVRLLSVYLRQVTF
                     LPYLVPGIAFAAAYLSLFAVPRGPMPALYGTVVILVLALIADQMPYASRAGISAMTQL
                     GKDPEEAAQIAGAGWLRRMTSIVIPIQKGSLVTGVLLPFISGIKGLSLFVILAVPSTD
                     VLTTYSLRLVDYHYTQAANAVVLIIAAIAYLGTLIAQKLTRTNLAEGLGS"
     misc_feature    complement(411412..413148)
                     /locus_tag="Smed_3963"
                     /note="ABC-type Fe3+ transport system, permease component
                     [Inorganic ion transport and metabolism]; Region: ThiP;
                     COG1178"
                     /db_xref="CDD:224099"
     misc_feature    complement(412315..412929)
                     /locus_tag="Smed_3963"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(412315..412320,412327..412332,
                     412339..412344,412348..412353,412360..412365,
                     412393..412398,412438..412443,412450..412461,
                     412480..412482,412489..412494,412534..412536,
                     412585..412587,412594..412599,412609..412611,
                     412615..412620,412627..412629,412633..412635,
                     412639..412644,412759..412761,412765..412770,
                     412777..412806,412810..412821,412849..412851,
                     412864..412869,412876..412881))
                     /locus_tag="Smed_3963"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(412444..412461,412759..412803))
                     /locus_tag="Smed_3963"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(412363..412365,412393..412395,
                     412402..412404,412441..412443,412657..412659,
                     412759..412761))
                     /locus_tag="Smed_3963"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(412513..412515,412525..412530,
                     412546..412584))
                     /locus_tag="Smed_3963"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(411520..412017)
                     /locus_tag="Smed_3963"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(411520..411525,411562..411567,
                     411574..411585,411604..411606,411613..411618,
                     411658..411660,411709..411711,411718..411723,
                     411733..411735,411739..411744,411751..411753,
                     411757..411759,411766..411771,411844..411846,
                     411850..411855,411862..411891,411895..411897,
                     411901..411909,411937..411939,411952..411957,
                     411964..411969))
                     /locus_tag="Smed_3963"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(411568..411585,411844..411888))
                     /locus_tag="Smed_3963"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(411520..411522,411529..411531,
                     411565..411567,411784..411786,411844..411846))
                     /locus_tag="Smed_3963"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(411637..411639,411649..411654,
                     411670..411708))
                     /locus_tag="Smed_3963"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            413700..414686
                     /locus_tag="Smed_3964"
                     /db_xref="GeneID:5319062"
     CDS             413700..414686
                     /locus_tag="Smed_3964"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     SMART: regulatory protein LacI;
                     KEGG: sme:SMb20154 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001312706.1"
                     /db_xref="GI:150376110"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5319062"
                     /translation="MARTFVTAEEVAKRAGVSRSAVSRTFTPGASVSKAVRRKVLKAA
                     GELGYRVNRLAQVLNNDRSNLIGVVGANLSSPFISKQLDLLSIGLLRQGKQCLLLNAA
                     DARQDIAPLIELLFEFRAQAIVVLSGEPPGSIVDECIANGVRLILINQRLDRTDTNMV
                     LSDDSHGADLAALRLIKANCRKVAVVTSGSQTPAQLRRANAFTQRMQAEGVEVVAWSG
                     GPTSYESGLQAGRELLADKAIDGAFCVTDLLALGFLDAARLEMNRRVPQDISILGFDD
                     IPQAGWKSYELTTVAQSFESLTEKVLSALDSDDLETRLQVVPVTLVERQTAR"
     misc_feature    413715..414683
                     /locus_tag="Smed_3964"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    413727..413873
                     /locus_tag="Smed_3964"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(413748..413762,413766..413771,413778..413780,
                     413793..413798,413805..413807,413844..413846,
                     413853..413855,413862..413867,413871..413873)
                     /locus_tag="Smed_3964"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    413844..413873
                     /locus_tag="Smed_3964"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    413892..414677
                     /locus_tag="Smed_3964"
                     /note="Ligand-binding domain of uncharacterized
                     DNA-binding regulatory proteins that are members of the
                     LacI-GalR family of bacterial transcription repressors;
                     Region: PBP1_LacI_like_2; cd06278"
                     /db_xref="CDD:107273"
     misc_feature    order(413892..413894,413931..413939,413946..413951,
                     413955..413960,413979..413993,413997..413999,
                     414030..414032,414039..414041,414048..414056,
                     414369..414371,414450..414452,414462..414464,
                     414471..414476)
                     /locus_tag="Smed_3964"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:107273"
     misc_feature    order(413928..413933,413940..413942,414075..414077,
                     414144..414146,414183..414185,414291..414293,
                     414360..414362,414522..414524,414573..414575)
                     /locus_tag="Smed_3964"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107273"
     gene            complement(414748..416391)
                     /locus_tag="Smed_3965"
                     /db_xref="GeneID:5319063"
     CDS             complement(414748..416391)
                     /locus_tag="Smed_3965"
                     /note="TIGRFAM: sodium-dependent inorganic phosphate (Pi)
                     transporter;
                     PFAM: Na+cotransporter;
                     KEGG: sme:SMb20153 hypothetical protein transmembrane"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent inorganic phosphate (Pi)
                     transporter"
                     /protein_id="YP_001312707.1"
                     /db_xref="GI:150376111"
                     /db_xref="InterPro:IPR003841"
                     /db_xref="GeneID:5319063"
                     /translation="MESVIVGANLFGAVALLLYGLGQVKDGMSRAWGARLRTGLAAGT
                     RGGARSFAAGFVATIALQSSTATALMVASFVEKELIAPAMAQVVLLGANVGTAATAWI
                     VALGLGWLSPLLIVAGVALSRTRSSARRGAGSAIVGIGLMLLSLHLLANATDPLRQSP
                     ALSAFLAMLENAWPVALFFAAGLAVLASSSLAIVVLILSLSATGGLSTALVIVLVLGA
                     NLGGAVPPVLATLGASASARRVTIGNLIVRAAGCAIALPLAGYGAYLMELARLSPQKL
                     AVDAHLLFNLAVALAAFPLSPLLYRLTASLIPEEAESENGPRYLDMEALARPVAALAG
                     AGREVMSVGDLIESMLVRALEALRGNDLSRLADISLLEGRVDRIQHEIKLYVSKVGKD
                     GMTDEDHRRARQIVDYAINLEHIGDIIEKGLHPEIAKKISLGLRFSEDGQGELGRLFA
                     ITLDNLRMAQAVFATGDAELARRLVEVKEEVRRLEKQSAECHLQRLREGRLDSIQTSS
                     LHLDMLRDLKRINAHVASVAHPILVGSGLLIDSRIRQAV"
     misc_feature    complement(414796..416391)
                     /locus_tag="Smed_3965"
                     /note="Na+/phosphate symporter [Inorganic ion transport
                     and metabolism]; Region: NptA; COG1283"
                     /db_xref="CDD:224202"
     misc_feature    complement(<416038..416346)
                     /locus_tag="Smed_3965"
                     /note="Na+/Pi-cotransporter; Region: Na_Pi_cotrans;
                     pfam02690"
                     /db_xref="CDD:202351"
     misc_feature    complement(415129..415377)
                     /locus_tag="Smed_3965"
                     /note="PhoU domain; Region: PhoU; pfam01895"
                     /db_xref="CDD:216770"
     misc_feature    complement(414799..415059)
                     /locus_tag="Smed_3965"
                     /note="PhoU domain; Region: PhoU; pfam01895"
                     /db_xref="CDD:216770"
     gene            complement(416464..418182)
                     /locus_tag="Smed_3966"
                     /db_xref="GeneID:5319064"
     CDS             complement(416464..418182)
                     /locus_tag="Smed_3966"
                     /note="PFAM: metallophosphoesterase;
                     KEGG: sme:SMb20152 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="YP_001312708.1"
                     /db_xref="GI:150376112"
                     /db_xref="InterPro:IPR004843"
                     /db_xref="GeneID:5319064"
                     /translation="MLKRALPAVAVIADAHFHDLEADFGFDRVEVEGRKITMRSWAET
                     RKSTRVFNESADAFLAALAEVRRRGIRHVVLLGDYTDDGQRATTGALRNILDEHSAFG
                     MSFYALPGNHDIFGPQGRHHTKQFLDCAGRGILVTSDVKRAGSGVTVSDRMYCEGYPA
                     GLDPMAGFGYFRKPEYLHWETPFGMSDAAEDREYEVASPDGRNRYNMMDASYLVEPEP
                     GLWLLMIDANVFEPVNGVYEWGDEAAFIDSTSGGWNAMLRCKPFVIPWIADVCARAER
                     LGKTLLAFSHYPVLDSFDGATGAEGALFGETNIARRTPRRAVERALLAAGLSLHFSGH
                     LHVEGVTRRGSGDRSLTNVAVPSLVAFPPAFKIAHPGEGNVAVETVELSGLPVHPRLR
                     NAYEREAALLGEEPDDAFSAPSYGAFLRAHKRALVSHRYFPEEWPPAIVERVADLTLE
                     EIACLFTGESAGSAPKLSALGQASAIDIAELGRLPMIELVADWYCLRQGASLALAHIE
                     ESRLPLYRFLADRFGCEPQTCHDSPEKGFVAIFLGALGLFLERAGNSQAHIVVQSNPA
                     RQDASA"
     misc_feature    complement(<417799..418035)
                     /locus_tag="Smed_3966"
                     /note="Predicted phosphohydrolases [General function
                     prediction only]; Region: Icc; COG1409"
                     /db_xref="CDD:224327"
     misc_feature    complement(<417844..418029)
                     /locus_tag="Smed_3966"
                     /note="metallophosphatase superfamily, metallophosphatase
                     domain; Region: MPP_superfamily; cl13995"
                     /db_xref="CDD:246597"
     misc_feature    complement(416836..>417438)
                     /locus_tag="Smed_3966"
                     /note="Predicted phosphohydrolases [General function
                     prediction only]; Region: Icc; COG1409"
                     /db_xref="CDD:224327"
     gene            complement(418176..418793)
                     /locus_tag="Smed_3967"
                     /db_xref="GeneID:5319065"
     CDS             complement(418176..418793)
                     /locus_tag="Smed_3967"
                     /note="KEGG: sme:SMb20151 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dual specificity protein phosphatase"
                     /protein_id="YP_001312709.1"
                     /db_xref="GI:150376113"
                     /db_xref="InterPro:IPR000387"
                     /db_xref="GeneID:5319065"
                     /translation="MDAPVHDRPAISPIAEGLGPHGSALYIGGSEGARDLGLLRRHGI
                     TTVVNCAINLDINYVETPSDEPDVERLAAGFAGIRYYKLGMIDGEGSPETMMLGAYYI
                     LDGALRQSMPKRPTYPFRDGGNLLVNCRGGRSRSVALVSLFLHKQQPELYPTLDDAVA
                     AIRERRQLMQDEWFETPKPMLYEAARKASAWIDLIERARHGDPQC"
     misc_feature    complement(418296..418721)
                     /locus_tag="Smed_3967"
                     /note="Protein tyrosine phosphatases (PTP) catalyze the
                     dephosphorylation of phosphotyrosine peptides; they
                     regulate phosphotyrosine levels in signal transduction
                     pathways. The depth of the active site cleft renders the
                     enzyme specific for phosphorylated Tyr; Region: PTPc;
                     cl00053"
                     /db_xref="CDD:241574"
     misc_feature    complement(order(418386..418391,418398..418400,
                     418407..418412,418533..418535))
                     /locus_tag="Smed_3967"
                     /note="active site"
                     /db_xref="CDD:238073"
     misc_feature    complement(order(418407..418409,418533..418535))
                     /locus_tag="Smed_3967"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:238073"
     gene            complement(418829..419689)
                     /locus_tag="Smed_3968"
                     /db_xref="GeneID:5319066"
     CDS             complement(418829..419689)
                     /locus_tag="Smed_3968"
                     /EC_number="3.1.3.25"
                     /note="PFAM: inositol monophosphatase;
                     KEGG: sme:SMb20150 putative inositol monophosphatase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-phosphate phosphatase"
                     /protein_id="YP_001312710.1"
                     /db_xref="GI:150376114"
                     /db_xref="InterPro:IPR000760"
                     /db_xref="GeneID:5319066"
                     /translation="MDRQFFSDDLHGRAELCRDVIRSAGALVLRGFLGNGRRSVSMKG
                     PQDFLTEVDAASEAHIRCALAAHFPEDSFFGEEGGGAISERVWVVDPIDGTANYARGI
                     PHFCISIAFVQSGSTEIAAIYNPAQDELYFARRGQGATRNGVPIHVAQTARFDAASLE
                     MGWSMRVPNTAYLGVMEALLGMGANVRRAGSGALALAYVADGRSDGYIELHMNSWDCL
                     AGLLLVSEAGGVVCPYLEIGSLDAGGPALAVAPALASETSRASNIPLDAAVIPACRQT
                     APACPATFVD"
     misc_feature    complement(418988..419662)
                     /locus_tag="Smed_3968"
                     /note="Archaeal fructose-1,6-bisphosphatase and related
                     enzymes of inositol monophosphatase family [Carbohydrate
                     transport and metabolism]; Region: SuhB; COG0483"
                     /db_xref="CDD:223559"
     misc_feature    complement(418994..419635)
                     /locus_tag="Smed_3968"
                     /note="IMPase, inositol monophosphatase and related
                     domains. A family of Mg++ dependent phosphatases,
                     inhibited by lithium, many of which may act on inositol
                     monophosphate substrate. They dephosphorylate inositol
                     phosphate to generate inositol, which may be...; Region:
                     IMPase; cd01639"
                     /db_xref="CDD:238817"
     misc_feature    complement(order(419042..419047,419405..419422,
                     419459..419464,419531..419533,419549..419551,
                     419561..419563))
                     /locus_tag="Smed_3968"
                     /note="active site"
                     /db_xref="CDD:238817"
     misc_feature    complement(order(419075..419086,419096..419098,
                     419120..419140,419150..419152,419159..419164,
                     419171..419173,419201..419206,419210..419212,
                     419216..419224,419378..419395,419399..419404,
                     419546..419548,419552..419554))
                     /locus_tag="Smed_3968"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238817"
     gene            complement(419904..420734)
                     /locus_tag="Smed_3969"
                     /db_xref="GeneID:5319067"
     CDS             complement(419904..420734)
                     /locus_tag="Smed_3969"
                     /note="PFAM: alpha/beta hydrolase fold;
                     KEGG: ret:RHE_CH02571 probable chloride peroxidase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold protein"
                     /protein_id="YP_001312711.1"
                     /db_xref="GI:150376115"
                     /db_xref="InterPro:IPR000073"
                     /db_xref="InterPro:IPR000639"
                     /db_xref="InterPro:IPR003089"
                     /db_xref="GeneID:5319067"
                     /translation="MTKNFITTEDGVEIFYKDWGSGQPIVFHHGWPLSSDDWDAQMLY
                     FLSKGYRVIAHDRRGHGRSTQISDGHDIAHYAADVAALATELDLRDTIHIGHSTGGGE
                     ALAYVARHGAGRVAKLVMVGAVPPIMLKTEAYPGGLPMEVFDGLRAQLAANRSQFFLD
                     LPSGPFYGFNRPDAKVSTGAIQNWWRQGMMGSAKAHYEGIKAFSETDFTEDLKKIEVP
                     TLVMHGDDDQIVPIDSSARLAVKLLKNGTLKVYEGYPHGMLTTHADVINPDLLAFIKG
                     "
     misc_feature    complement(419907..420722)
                     /locus_tag="Smed_3969"
                     /note="Predicted hydrolases or acyltransferases
                     (alpha/beta hydrolase superfamily) [General function
                     prediction only]; Region: MhpC; COG0596"
                     /db_xref="CDD:223669"
     misc_feature    complement(420489..420704)
                     /locus_tag="Smed_3969"
                     /note="Putative lysophospholipase; Region: Hydrolase_4;
                     pfam12146"
                     /db_xref="CDD:221442"
     misc_feature    complement(419955..>420098)
                     /locus_tag="Smed_3969"
                     /note="Prolyl oligopeptidase family; Region: Peptidase_S9;
                     pfam00326"
                     /db_xref="CDD:215859"
     gene            complement(420931..422538)
                     /locus_tag="Smed_3970"
                     /db_xref="GeneID:5319068"
     CDS             complement(420931..422538)
                     /locus_tag="Smed_3970"
                     /note="PFAM: protein of unknown function DUF894 DitE;
                     major facilitator superfamily MFS_1;
                     KEGG: sme:SMa1814 putative dioxygenase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312712.1"
                     /db_xref="GI:150376116"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR010290"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5319068"
                     /translation="MKAAGLEGTGTFAPLRQQVFAVLWVATIIGNTGSFIRDVASSWL
                     VTELSATPAAVSLVQAAATLPVFLLAIPAGVLSDILDRRKFLIAVQLLLASASLCLLT
                     LSAMGLQSVSSLVALTFIGGIGAALVAPTWQAIVPELVQRQDVKGAVALNSLGINISR
                     AIGPALGGLLLAWFGAAVTYGVDVITYVFVVAALLWWRRGTPEDDALAERFFGAFRAG
                     LRYARSSRELHVVLIRAAVFFAFSSAIWALLPLVARQLLGGDASFYGMLLGAVGAGAV
                     CGALVMPRLRARLDADGLLLAAAIVTAAVMGVLSLAPPQWAAVAALLACGAAWITALT
                     TLNSTAQSILPNWVRGRSLAVYLTVFNGAMTGGSLAWGAIAEAVGVPSALGIAAIGLL
                     CVGLGFHRVKLPRGEAELVPSNHWPEPLTAQPVENDRGPVLILIEYIVDRKDRPAFLK
                     ALASLSHERRRDGAYGWGVTEDAADPSRVVEWFTVESWAEHMRQHRRVSKADADVQQE
                     VRAYHQGLEPPAVQHLLAINRPHIKGK"
     misc_feature    complement(420949..422514)
                     /locus_tag="Smed_3970"
                     /note="Transmembrane secretion effector; Region: MFS_3;
                     pfam05977"
                     /db_xref="CDD:218836"
     misc_feature    complement(421333..422481)
                     /locus_tag="Smed_3970"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(order(421447..421449,421456..421461,
                     421468..421473,421480..421485,421516..421518,
                     421525..421530,421540..421542,421549..421554,
                     421561..421563,421705..421707,421717..421719,
                     421726..421728,421738..421740,421747..421749,
                     421789..421791,421798..421803,421810..421812,
                     421816..421818,421825..421827,422059..422061,
                     422077..422082,422089..422094,422128..422130,
                     422137..422142,422149..422154,422161..422166,
                     422317..422322,422326..422331,422341..422343,
                     422350..422355,422362..422364,422413..422418,
                     422422..422430,422437..422439))
                     /locus_tag="Smed_3970"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(422535..422978)
                     /locus_tag="Smed_3971"
                     /db_xref="GeneID:5319069"
     CDS             complement(422535..422978)
                     /locus_tag="Smed_3971"
                     /note="PFAM: DoxX family protein;
                     KEGG: sme:SMa1817 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="YP_001312713.1"
                     /db_xref="GI:150376117"
                     /db_xref="InterPro:IPR011592"
                     /db_xref="InterPro:IPR011637"
                     /db_xref="GeneID:5319069"
                     /translation="MTNISLRDARPVRSSVSGLHFLALLALCSAYIQGPLIKIFDFSG
                     AIAEMDHFGLYPAPFFAVGVIVFELSMSALILTGFYRRAAALALALFTFATTFIAFRF
                     WDLQPGLERSMAMNGFFEHFGLVGAFVLVALYEPRRRPAARRSFR"
     misc_feature    complement(422577..422918)
                     /locus_tag="Smed_3971"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG2259"
                     /db_xref="CDD:225168"
     gene            complement(422990..424867)
                     /locus_tag="Smed_3972"
                     /db_xref="GeneID:5319070"
     CDS             complement(422990..424867)
                     /locus_tag="Smed_3972"
                     /note="PFAM: Amidohydrolase 3;
                     KEGG: rle:pRL120453 putative transcriptional regulatory
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase 3"
                     /protein_id="YP_001312714.1"
                     /db_xref="GI:150376118"
                     /db_xref="InterPro:IPR013108"
                     /db_xref="GeneID:5319070"
                     /translation="MSADLILHRGLVTTLDAAKPNATAIAVKDGRFLAVGLDQEVMAL
                     AGPDTKVVDLKGKRVLPGLNDNHTHVVRGGLNFNMELRWDGVRSLADAMNMLKRQVAI
                     TPPPQWVRVVGGFTEHQFIEKRLPTIDEINAIAPDTPVFLLHLYDRALLNGAALRAVG
                     YGKDTPDPPGGEITRDARGNPTGLLIAKPNAGILYSTLAKGPKLPLEYQVNSTRHFMR
                     ELNRLGITSVIDAGGGFQNYPDDYAVIQKLADEGQMTVRLAYNLFTQKPKEEKEDFLK
                     WTSSVKYKQGDDFFRHNGAGEMLVFSAADFEDFREPRPEMAPEMEGELEEVVRILAEN
                     RWPWRLHATYDETISRALDVFEKVNQDIPLAGINWFFDHAETISDSSIDRIAALGGGI
                     AVQHRMAYQGEYFVERYGHGAAEATPPVARMLDKGVKVSAGTDATRVASYNPWVSLSW
                     LVTGKTVGGMQLYPRANCLDRETALRMWTEKVQWFSNEEGRKGRIEKGQLADLIVPAK
                     DYFTCAEDEISFLTADLTMVGGRIVYAANDFASLDENPLPPAMPDWSPVRNYGGYAAW
                     GEPEGAGRHSLKRTAIASCGCASNCGVHGHDHAGAWTSRLPVADLKGFFGALGCSCWA
                     V"
     misc_feature    complement(423257..424867)
                     /locus_tag="Smed_3972"
                     /note="Predicted metal-dependent hydrolase with the
                     TIM-barrel fold [General function prediction only];
                     Region: COG1574"
                     /db_xref="CDD:224490"
     misc_feature    complement(423353..424798)
                     /locus_tag="Smed_3972"
                     /note="YtcJ_like metal dependent amidohydrolases. YtcJ is
                     a Bacillus subtilis ORF of unknown function. The
                     Arabidopsis homolog LAF3 has been identified as a factor
                     required for photochrome A signalling; Region: YtcJ_like;
                     cd01300"
                     /db_xref="CDD:238625"
     misc_feature    complement(order(423563..423565,423749..423751,
                     423845..423847,424661..424663,424667..424669))
                     /locus_tag="Smed_3972"
                     /note="active site"
                     /db_xref="CDD:238625"
     gene            complement(424975..425259)
                     /locus_tag="Smed_3973"
                     /db_xref="GeneID:5318106"
     CDS             complement(424975..425259)
                     /locus_tag="Smed_3973"
                     /note="PFAM: protein of unknown function DUF1427;
                     KEGG: sme:SMa1820 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312715.1"
                     /db_xref="GI:150376119"
                     /db_xref="InterPro:IPR009872"
                     /db_xref="GeneID:5318106"
                     /translation="MKMYLLSLGAGLLVGVIYSLLNIRSPAPPVIALVGLLGILVGEQ
                     AVPLVKRLLSGNPVTVSWVHSRCAPHVFGNLPTGADDGGMRDRPANTELS"
     misc_feature    complement(424990..425259)
                     /locus_tag="Smed_3973"
                     /note="Protein of unknown function (DUF1427); Region:
                     DUF1427; cl01771"
                     /db_xref="CDD:242700"
     gene            complement(425341..425997)
                     /locus_tag="Smed_3974"
                     /db_xref="GeneID:5318107"
     CDS             complement(425341..425997)
                     /locus_tag="Smed_3974"
                     /note="PFAM: isochorismatase hydrolase;
                     KEGG: sme:SMa1821 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase hydrolase"
                     /protein_id="YP_001312716.1"
                     /db_xref="GI:150376120"
                     /db_xref="InterPro:IPR000868"
                     /db_xref="GeneID:5318107"
                     /translation="MTLNATPTPGNLLVSPNDHTLIMIDFQSQMAFATKSIDAVLLRN
                     NAALVANAAAGFGVSTVLTTVAEKTFSGPMFSEITDAFPGQALLDRTSMNTWEDAAVI
                     EEVNRIGRKRLVFCGLWTSVCIVGPTLSALDQGFEVYVIADACGDVSDEAHERAMDRM
                     VQAGVRPMTSLQYMLELQRDWARTESYEMTTGIARKFGGAYGLGIIYAKSMFGASEGH
                     "
     misc_feature    complement(425461..425940)
                     /locus_tag="Smed_3974"
                     /note="YcaC related amidohydrolases; E.coli YcaC is an
                     homooctameric hydrolase with unknown specificity. Despite
                     its weak sequence similarity, it is structurally related
                     to other amidohydrolases and shares conserved active site
                     residues with them; Region: YcaC_related; cd01012"
                     /db_xref="CDD:238494"
     misc_feature    complement(order(425629..425631,425728..425730,
                     425923..425925))
                     /locus_tag="Smed_3974"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238494"
     misc_feature    complement(order(425767..425769,425905..425907,
                     425914..425916))
                     /locus_tag="Smed_3974"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238494"
     misc_feature    complement(425488..>425784)
                     /locus_tag="Smed_3974"
                     /note="Isochorismatase family; Region: Isochorismatase;
                     pfam00857"
                     /db_xref="CDD:216156"
     misc_feature    complement(425641..425646)
                     /locus_tag="Smed_3974"
                     /note="conserved cis-peptide bond; other site"
                     /db_xref="CDD:238494"
     gene            complement(426118..427026)
                     /locus_tag="Smed_3975"
                     /db_xref="GeneID:5318108"
     CDS             complement(426118..427026)
                     /locus_tag="Smed_3975"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type;
                     KEGG: sme:SMa1822 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="YP_001312717.1"
                     /db_xref="GI:150376121"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="GeneID:5318108"
                     /translation="MTNASSDVAGPRPRDSLGCSVEKLDEDRTIDGGNMTFHRKRSAR
                     APAGRVSTPATGRGYLIGVSASGGHRRRIIREHHSTVHDFEENSIYVRTFSDDYRADL
                     NGSFDFMLLEVSHSALERITDGADIKGVTELNSVAGHADPVLGGMLGALFATVDGQAG
                     RSALFVDQLSAAIGIHLVRQYGNGRGRAAGKGRRLSMRSQSLLKDLAQSRLAGDLTVE
                     ELAGICQLSQATFLRAFRETLGKTPHQWLSQQRIEKAIHLLEFTQAPLREIATLCGFS
                     DQSHFTRAFVQAMGATPGVWRRHRQS"
     misc_feature    complement(426286..426405)
                     /locus_tag="Smed_3975"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     misc_feature    complement(426136..426387)
                     /locus_tag="Smed_3975"
                     /note="helix_turn_helix, arabinose operon control protein;
                     Region: HTH_ARAC; smart00342"
                     /db_xref="CDD:197666"
     misc_feature    complement(426133..426261)
                     /locus_tag="Smed_3975"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     gene            complement(427192..428202)
                     /locus_tag="Smed_3976"
                     /db_xref="GeneID:5318109"
     CDS             complement(427192..428202)
                     /locus_tag="Smed_3976"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type;
                     KEGG: sme:SMa1823 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="YP_001312718.1"
                     /db_xref="GI:150376122"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="GeneID:5318109"
                     /translation="MVVGSCSLYPVTDSCESAARSGRVARQTGNRRPTPMALHQESNA
                     VDSQGPIIRSITSGDISVTRVCSDRYDLKAAPATPCAEAFSVIVQLRDFEAHRLWKAG
                     KLVYEGGHSRASLAITDLRDRWQCHHLSPFDNIRFQIPFARMSAFAKQAGRNEYLGLA
                     SVQGRIDPVMYGLAQALLPSLESPETASSLFLEQINLAVLAHLSQTYGGLHFPIGKKG
                     TLAPWQERLATEFLANHFNKPFSLGELARLCELSRSYFNKAFKESFGRTPSRWLSEYR
                     TGRVKELLLQDVPIAEAAIACGFADQSHLTRVFTGLTGETPARYRRKNRCARPAMEQL
                     SG"
     misc_feature    complement(427387..427509)
                     /locus_tag="Smed_3976"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     misc_feature    complement(427234..427470)
                     /locus_tag="Smed_3976"
                     /note="Helix-turn-helix domain; Region: HTH_18; pfam12833"
                     /db_xref="CDD:221799"
     misc_feature    complement(427237..427365)
                     /locus_tag="Smed_3976"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     gene            complement(428287..429192)
                     /locus_tag="Smed_3977"
                     /db_xref="GeneID:5318110"
     CDS             complement(428287..429192)
                     /locus_tag="Smed_3977"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type;
                     KEGG: sme:SMa1825 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="YP_001312719.1"
                     /db_xref="GI:150376123"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="GeneID:5318110"
                     /translation="MSLRMIAEEKVGVFFGEPESPCLVARPVHAAKFSVTRLQCRLDG
                     RASRLVRLPADDAYFLMLYLDDALHRDVAGDGTECEVRRYREGSVCLVDLTHGASIRL
                     VSDLDSLAFYMPRDLFREVSKVANAPRATGLRCRRGEDDDVMRNLGTALLPFFDEQGR
                     GQNAVLQHIAIAVCAHLLHSYTDPGEARGGVAGLSVWQEKAAKDFMIEHFAEDFSFAA
                     AAAAAGLSKRDFINGFSDVAGLTPSQWLMRHRIVRAKQYLTSRALTLSEVAKRCGFSD
                     VDQFDRAFRRATGTSPSDWRGRWLN"
     misc_feature    complement(428299..428523)
                     /locus_tag="Smed_3977"
                     /note="Helix-turn-helix domain; Region: HTH_18; pfam12833"
                     /db_xref="CDD:221799"
     misc_feature    complement(428305..428418)
                     /locus_tag="Smed_3977"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     gene            429257..429394
                     /locus_tag="Smed_3978"
                     /pseudo
                     /db_xref="GeneID:5318111"
     gene            429562..430386
                     /locus_tag="Smed_3979"
                     /db_xref="GeneID:5318112"
     CDS             429562..430386
                     /locus_tag="Smed_3979"
                     /EC_number="1.11.1.6"
                     /note="PFAM: manganese containing catalase;
                     KEGG: rba:RB10727 manganese-containing catalase"
                     /codon_start=1
                     /transl_table=11
                     /product="catalase"
                     /protein_id="YP_001312720.1"
                     /db_xref="GI:150376124"
                     /db_xref="InterPro:IPR007760"
                     /db_xref="GeneID:5318112"
                     /translation="MFYTDGKLQYPVRVEKANPLFARALQQAIGGIEGEIRVAMQYFF
                     QACGARGDPKFRDLLMNTAAEELGHIEMLATAVALNLEGAPLSLKEQVANDPISGAVL
                     GGMNLKNLLSAGLSAMPVDSDGVPFDMSHIYASGNIAADMVANVAAESTGRALAVRLY
                     EMTDDPGMKDMLSYLIARDTMHQNQWLAAIEELGGGQGVFPIPNSFPQDQEQQEFSYA
                     FLGFQQDGSDPVAGRWSQGTSIDGKGSFKAGSIMPMGEKPQLAPAKPRGGAQKEQM"
     misc_feature    429562..430143
                     /locus_tag="Smed_3979"
                     /note="Manganese catalase, ferritin-like diiron-binding
                     domain; Region: Mn_catalase; cd01051"
                     /db_xref="CDD:153110"
     misc_feature    order(429664..429666,429757..429759,429766..429768,
                     430006..430008,430105..430107)
                     /locus_tag="Smed_3979"
                     /note="dimanganese center [ion binding]; other site"
                     /db_xref="CDD:153110"
     gene            430576..431637
                     /locus_tag="Smed_3980"
                     /db_xref="GeneID:5318113"
     CDS             430576..431637
                     /locus_tag="Smed_3980"
                     /note="KEGG: sme:SMb20149 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312721.1"
                     /db_xref="GI:150376125"
                     /db_xref="GeneID:5318113"
                     /translation="MTTMGSHRLLMLVILADDLTGALDSAAPFAGRGLHTEVALALES
                     VDAALADQPEVLVVNVKSREVSPDEARMATSDVLKHVPDDARIFKKVDSRLKGNIEVE
                     LDAIRYNRALVAPAIPDFGRVVAGGHVRGFGVNAPIPIAERLGRHAESALIPDTTSRD
                     DMLAAVETGEAAGCDLMIGARGLAEALAHRMTGGAGLPLMSVPQEPILIVVGSRDPIT
                     VEQVGVLREDYAVGYFPAVGGRVQQEAGRPAEMVTVIQAVEGEMPLSPSEVSVNLAES
                     VVPAFTGRASTLLLTGGATAEAVLARLGVSRFRLLGECMPGMALAFADGRYIITKSGG
                     FGRRDTLSDIARQILGEAR"
     misc_feature    430606..431622
                     /locus_tag="Smed_3980"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3395"
                     /db_xref="CDD:225930"
     gene            431641..432342
                     /locus_tag="Smed_3981"
                     /db_xref="GeneID:5318114"
     CDS             431641..432342
                     /locus_tag="Smed_3981"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20148 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312722.1"
                     /db_xref="GI:150376126"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318114"
                     /translation="MGLQEGTPRKGLPDIVFERMHRAIKSGAYKPDERLPTEHELATE
                     FEVSRPIVREALRRLREQGLIYSRRGAGSFVRATGLREPLGFGQLENVADLLNCYEFR
                     LTLEPAAAAAAALRHDETSLAAIRRALELLRDATNRQSHREDADFQFHLAIARAAQNS
                     YFSTAMEALKEHIAVGMKFHGISVKREASGLSRVFAEHEAIADAIAAGNAEDARILML
                     KHLTGSRDRLFLASQ"
     misc_feature    431659..432339
                     /locus_tag="Smed_3981"
                     /note="Transcriptional regulators [Transcription]; Region:
                     FadR; COG2186"
                     /db_xref="CDD:225097"
     misc_feature    431686..431868
                     /locus_tag="Smed_3981"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    order(431746..431748,431752..431757,431779..431793,
                     431797..431802,431809..431811,431839..431844,
                     431848..431859)
                     /locus_tag="Smed_3981"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    431935..>432162
                     /locus_tag="Smed_3981"
                     /note="This entry represents the C-terminal ligand binding
                     domain of many members of the GntR family; Region: FCD;
                     smart00895"
                     /db_xref="CDD:214892"
     gene            complement(432757..433863)
                     /locus_tag="Smed_3982"
                     /db_xref="GeneID:5318115"
     CDS             complement(432757..433863)
                     /locus_tag="Smed_3982"
                     /note="PFAM: iron-containing alcohol dehydrogenase;
                     KEGG: sme:SMb20147 putative alcohol dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="YP_001312723.1"
                     /db_xref="GI:150376127"
                     /db_xref="InterPro:IPR001670"
                     /db_xref="GeneID:5318115"
                     /translation="MITIHQPRRLVVGAGNISQVGTWAAEVASTLVIATPITSGFAER
                     LQLPGKLTLFDAIPGEPDIATLDAALDAARKARPDLIVGLGGGSVMDVAKLVAVLWDS
                     GQSLADVAGPNRVAGRNVRLAQVATTAGTGSEAGIRSLITDPGKGSKIAVESPHMIAD
                     LAVLDPELTYSVPPAVTAATGVDAMAHCVEAFTNRKSHPMIDGFARMGFNLVGKYLAR
                     AVRDGEDTEAREGMMLASYYGGICLGPVNTAAGHAISYPLGTLLHLPHGLANAIIFPH
                     VLAFNQPVVSAKTAEVADALGLGQGLSQRDLLSAARDFCAGLGIEMSLAANGAKGADL
                     PRFAADAHSIRRLMDNNPADMSEADVLEIYRAAF"
     misc_feature    complement(432760..433863)
                     /locus_tag="Smed_3982"
                     /note="Alcohol dehydrogenase, class IV [Energy production
                     and conversion]; Region: EutG; COG1454"
                     /db_xref="CDD:224371"
     misc_feature    complement(432769..433854)
                     /locus_tag="Smed_3982"
                     /note="Dehydroquinate synthase-like (DHQ-like) and
                     iron-containing alcohol dehydrogenases (Fe-ADH); Region:
                     DHQ_Fe-ADH; cl02872"
                     /db_xref="CDD:243222"
     misc_feature    complement(order(433066..433068,433096..433098,
                     433108..433110,433303..433305,433315..433317,
                     433336..433338,433360..433362,433414..433419,
                     433474..433476,433480..433485,433582..433584,
                     433591..433593,433600..433608,433759..433761))
                     /locus_tag="Smed_3982"
                     /note="active site"
                     /db_xref="CDD:173927"
     misc_feature    complement(order(433066..433068,433360..433362,
                     433474..433476,433480..433485,433600..433608,
                     433759..433761))
                     /locus_tag="Smed_3982"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:173927"
     misc_feature    complement(order(433066..433068,433108..433110,
                     433315..433317))
                     /locus_tag="Smed_3982"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:173927"
     gene            complement(433860..434825)
                     /locus_tag="Smed_3983"
                     /db_xref="GeneID:5317909"
     CDS             complement(433860..434825)
                     /locus_tag="Smed_3983"
                     /EC_number="1.1.1.262"
                     /note="TIGRFAM: 4-hydroxythreonine-4-phosphate
                     dehydrogenase;
                     PFAM: Pyridoxal phosphate biosynthetic protein PdxA;
                     KEGG: sme:SMb20146 4-hydroxythreonine-4-phosphate
                     dehydrogenase 2"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase"
                     /protein_id="YP_001312724.1"
                     /db_xref="GI:150376128"
                     /db_xref="InterPro:IPR005255"
                     /db_xref="GeneID:5317909"
                     /translation="MSNIIGITMGDPCGVGPEITVRSLAEMSAEDREATRIYGNLATL
                     EAARKALGVAVDLAPHVVDLPIEGAPLAWGSLSAVAGDAAFRFIERAVRDAEKGKIGC
                     IVTAPINKEALNMAGHHYDGHTGMLRSLTGSSAAYMLLASERLKVIHVSTHVSLKEAI
                     SRATTERVLATIRAGNAHLKRIGYERPRIAVAGINPHCGENGLFGTEDDDQIGPAVAA
                     AREEGIDVQGPISADTVFHRAYSGSFDLVVAQYHDQGHIPIKLVAFDTAVNVSVDLPI
                     DRTSVDHGTAFDIAGKGIANHGNLNSAIAYARKLVAGKASRKAAS"
     misc_feature    complement(433875..434825)
                     /locus_tag="Smed_3983"
                     /note="Pyridoxal phosphate biosynthesis protein [Coenzyme
                     metabolism]; Region: PdxA; COG1995"
                     /db_xref="CDD:224906"
     misc_feature    complement(433899..434816)
                     /locus_tag="Smed_3983"
                     /note="4-hydroxythreonine-4-phosphate dehydrogenase;
                     Validated; Region: pdxA; PRK03743"
                     /db_xref="CDD:179641"
     gene            complement(434822..436018)
                     /locus_tag="Smed_3984"
                     /db_xref="GeneID:5317910"
     CDS             complement(434822..436018)
                     /locus_tag="Smed_3984"
                     /note="KEGG: sme:SMb20145 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312725.1"
                     /db_xref="GI:150376129"
                     /db_xref="InterPro:IPR002860"
                     /db_xref="GeneID:5317910"
                     /translation="MTPEEIANAMTGKLREARDGRLESLLPSPTVQNHAAFLHRLEDG
                     SLVCAWFGGTLEGKSDISIFASVLAPGAERWGEPQRLSFDADHSEQNPVLFTAPDGRL
                     WLFHTSQPAGNQDECRIRMAAIERDPDDPTKLDAAEGRYLDLPRGCFIRAPLVVRDDG
                     AWLLPIFRCIQRPGQKWNGSHDNAAVGISTDGGERWRLADLEDSIGCVHMSPVPVGGD
                     GYAAFFRRRQADQVYRVESADGGRTWSLPAPTDVPNNNSSIAVIRLSDGRLAMICNPV
                     NAALSPDRRASLYDELGEDDGRPDADPSGGCVPIWGVPRAPVSVCLSDDGGRTFPERI
                     VIENGPGTCLSNNSTDGHNKEMSYPWLLEGDDGSLHIAYTFHRRAIKYVRLPPGWADR
                     TDGRIR"
     misc_feature    complement(434834..436018)
                     /locus_tag="Smed_3984"
                     /note="Predicted neuraminidase (sialidase) [Carbohydrate
                     transport and metabolism]; Region: COG4692"
                     /db_xref="CDD:227036"
     misc_feature    complement(434906..435889)
                     /locus_tag="Smed_3984"
                     /note="BNR repeat-like domain; Region: BNR_2; pfam13088"
                     /db_xref="CDD:221914"
     gene            436358..437857
                     /locus_tag="Smed_3985"
                     /db_xref="GeneID:5317911"
     CDS             436358..437857
                     /locus_tag="Smed_3985"
                     /note="PFAM: extracellular solute-binding protein family
                     5;
                     KEGG: sme:SMb20144 putative ABC transporter
                     oligopeptide-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312726.1"
                     /db_xref="GI:150376130"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="GeneID:5317911"
                     /translation="MKRSLLLGVLMLGSALSPAFGESGPIKIVLPEEADLLEPCMATR
                     SNIGRIIMQNVSETLTELDVRGGKGLMPRLAESWEQKEDGSWRFNLRKGVKFSDGTDF
                     NAKDVKYSFDRVMSDKNACESRRYFGGMNIKIDVVDDATIDFTVDPVQPILPLLLSLL
                     TIVPEETPMEFVREPVGTGPYELTDWTPGQQIVLTARDDYWGEKPEVTEATYLFRSDP
                     AVRAAMVQTGEADLSPSISQTEATNPATDFSYLDSETVYLRIDHNIEPLNDVRVRRAL
                     NLAIDREAFLGTLVPDSAVLATAIVPPPTLGWNPDVKVFPYDPDQAKKLIEEAKADGV
                     KVDTPITIIARTANFPNVTEIMEAIQAQLQEVGLQVELKFVEVAEHEVYYSKPFKDGR
                     GPQLVAAMHDNSKGDPSFSMFFKYDSEGTQSGFADPKVDDLIARANAAVGDERAKLWS
                     ELIAYVHDEVVADVLLFHMVGFSRVSERLDFKPTMATNSMLQLSEIKIK"
     sig_peptide     436358..436423
                     /locus_tag="Smed_3985"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 22"
     misc_feature    436409..437854
                     /locus_tag="Smed_3985"
                     /note="ABC-type dipeptide transport system, periplasmic
                     component [Amino acid transport and metabolism]; Region:
                     DdpA; COG0747"
                     /db_xref="CDD:223818"
     misc_feature    436433..437845
                     /locus_tag="Smed_3985"
                     /note="The substrate-binding component of an
                     uncharacterized ABC-type
                     nickel/dipeptide/oligopeptide-like import system contains
                     the type 2 periplasmic binding fold; Region:
                     PBP2_NikA_DppA_OppA_like_12; cd08491"
                     /db_xref="CDD:173856"
     gene            437990..438904
                     /locus_tag="Smed_3986"
                     /db_xref="GeneID:5317912"
     CDS             437990..438904
                     /locus_tag="Smed_3986"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20143 putative oligopeptide ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001312727.1"
                     /db_xref="GI:150376131"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5317912"
                     /translation="MLRFIRQRALASLISLIGLIVMVFFLSRMTGDPAALFLPVEASA
                     EMKDQFRELHGLNDPILVQFARYVGDVATGDLGQSLRKARPALDVVLEAFTWTLWLAI
                     ITMTLVTGAAIVVGSLGAFRSGGFFDRFSSMISLVGASVPDFWLAIVAIVIFSINFAI
                     LPTSGTGSVLHWILPIAVLFVRPFGIIVQVVRGAMVGALSSAYVKTARAKGVKSGPII
                     FIHALRNAMLPVITVVGDQAASLLNGAVVVETIFGFPGVGKLMIDSILQRDFNVVLAA
                     ILVTAIAIFLMNVLIDLAYALLDPRIRH"
     misc_feature    437990..438901
                     /locus_tag="Smed_3986"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppB; COG0601"
                     /db_xref="CDD:223674"
     sig_peptide     437990..438082
                     /locus_tag="Smed_3986"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.996) with cleavage site probability 0.990 at
                     residue 31"
     misc_feature    438269..438790
                     /locus_tag="Smed_3986"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(438317..438322,438329..438334,438350..438352,
                     438380..438391,438395..438424,438431..438436,
                     438440..438442,438533..438538,438542..438544,
                     438548..438550,438557..438562,438566..438568,
                     438578..438583,438590..438592,438641..438643,
                     438683..438688,438695..438697,438716..438727,
                     438734..438739,438764..438769)
                     /locus_tag="Smed_3986"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(438398..438442,438716..438733)
                     /locus_tag="Smed_3986"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(438440..438442,438518..438520,438734..438736,
                     438758..438760,438767..438769)
                     /locus_tag="Smed_3986"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(438593..438631,438647..438652,438662..438664)
                     /locus_tag="Smed_3986"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            438918..439841
                     /locus_tag="Smed_3987"
                     /db_xref="GeneID:5317913"
     CDS             438918..439841
                     /locus_tag="Smed_3987"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20142 putative oligopeptide ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312728.1"
                     /db_xref="GI:150376132"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5317913"
                     /translation="MTLATTDNVIAAEPSLLVRMMRMLLADKFALSAAIFLLVILAIA
                     IIGPSWLGDLATKQNLRGRNLPPFDWTRTWVWWMGADALGRPLFARIIVAAQNTLMVA
                     AGAVILSSVIGTVLGLIAGFSSPRTGQIIMRLADVIMSFPSLLIAVIVLYVLGSSILN
                     LMLVLAITRIPVYLRTTRAEVLEIRERMFVQAARVMGASSKRILFRHILPVVLPTLTT
                     LATLDFAYVMLAESALSFLGIGIQPPEITWGLMISQGRQYLTNAWWLSFWPGLAIILT
                     TMSLNLLSNWMRIALDPVQRWRLEMKGGKNG"
     misc_feature    439056..439811
                     /locus_tag="Smed_3987"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppC; COG1173"
                     /db_xref="CDD:224094"
     misc_feature    439200..439739
                     /locus_tag="Smed_3987"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(439248..439253,439260..439265,439278..439280,
                     439308..439319,439323..439352,439359..439364,
                     439368..439370,439419..439424,439428..439430,
                     439434..439436,439443..439448,439452..439454,
                     439464..439469,439476..439478,439527..439529,
                     439569..439574,439581..439583,439602..439613,
                     439620..439625,439662..439667,439695..439700,
                     439707..439712,439716..439721,439728..439733)
                     /locus_tag="Smed_3987"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(439326..439370,439602..439619)
                     /locus_tag="Smed_3987"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(439368..439370,439404..439406,439620..439622,
                     439656..439658,439665..439667,439695..439697)
                     /locus_tag="Smed_3987"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(439479..439517,439533..439538,439548..439550)
                     /locus_tag="Smed_3987"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            439834..441477
                     /locus_tag="Smed_3988"
                     /db_xref="GeneID:5317914"
     CDS             439834..441477
                     /locus_tag="Smed_3988"
                     /note="PFAM: ABC transporter related;
                     Oligopeptide/dipeptide ABC transporter domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20141 putative oligopeptide ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312729.1"
                     /db_xref="GI:150376133"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013563"
                     /db_xref="GeneID:5317914"
                     /translation="MAEHLLEVRNLSVEFHTAAGVVHAVKSISYHLDKGETLAILGES
                     GSGKSVSSSAIMNLIDMPPGRISGGEILLDGRDLLTMPAEERREVNGRRVAMIFQDPL
                     SHLNPVYSVGWQIAEAMTTHGLAGSKAREEGLRLLRRVGIPEPERAMRKYPHEFSGGQ
                     RQRVMIAMALALRPDLLIADEPTTALDVTVQAEVLKLLKELQRETGMAVLIITHDLGV
                     VAEIADRVVVMEKGTLVEAGTVREIYKNPQHPYTRKLIAAAPGKGVMHEPGARAEPLL
                     SVRDVRKTYGSFEALKGISFDLMPGETMAVVGESGSGKSTLARALLRLDEPDSGTALW
                     KGRDLFALSPSELYKLRRDLQMVFQDPTQSLNPRMTVFQLISEAWVIHPDILPKARWR
                     ERVAELLAQVGLSAEHMSRYPHQFSGGQRQRIAIARALALEPQLIICDEAVSALDVSV
                     QAQVIELLDKLRREMGIAFIFIAHDLPVVRDFADHVMVMQQGEIVELGTIREVFETPR
                     QAYTRALLAASLSPDPDAKAGCPEPPAADAEILIPKRSH"
     misc_feature    439834..441408
                     /locus_tag="Smed_3988"
                     /note="ATPase components of various ABC-type transport
                     systems, contain duplicated ATPase [General function
                     prediction only]; Region: COG1123"
                     /db_xref="CDD:224048"
     misc_feature    439846..440547
                     /locus_tag="Smed_3988"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    439957..439980
                     /locus_tag="Smed_3988"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    order(439966..439971,439975..439983,440128..440130,
                     440371..440376,440473..440475)
                     /locus_tag="Smed_3988"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    440119..440130
                     /locus_tag="Smed_3988"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    440299..440328
                     /locus_tag="Smed_3988"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    440359..440376
                     /locus_tag="Smed_3988"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    440383..440394
                     /locus_tag="Smed_3988"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    440461..440481
                     /locus_tag="Smed_3988"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    440536..>440658
                     /locus_tag="Smed_3988"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; pfam08352"
                     /db_xref="CDD:219806"
     misc_feature    440656..441327
                     /locus_tag="Smed_3988"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    440755..440778
                     /locus_tag="Smed_3988"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    order(440764..440769,440773..440781,440908..440910,
                     441151..441156,441253..441255)
                     /locus_tag="Smed_3988"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    440899..440910
                     /locus_tag="Smed_3988"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    441079..441108
                     /locus_tag="Smed_3988"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    441139..441156
                     /locus_tag="Smed_3988"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    441163..441174
                     /locus_tag="Smed_3988"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    441241..441261
                     /locus_tag="Smed_3988"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    441316..>441450
                     /locus_tag="Smed_3988"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     gene            441477..442367
                     /locus_tag="Smed_3989"
                     /db_xref="GeneID:5317915"
     CDS             441477..442367
                     /locus_tag="Smed_3989"
                     /note="PFAM: dihydrodipicolinate synthetase;
                     KEGG: sme:SMb20140 putative dihydrodipicolinate synthase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthetase"
                     /protein_id="YP_001312730.1"
                     /db_xref="GI:150376134"
                     /db_xref="InterPro:IPR002220"
                     /db_xref="GeneID:5317915"
                     /translation="MSKKAFVALVTCFNEDETINYAATRAQVRRQVAAGNNIMCAGTN
                     GDFTALTHEEKIRLTEEVVDEVGGRAEVIVNAGMPATFETLQLARAFDRIGVSGIAVI
                     TPFFIACTQDGLIRHFSTVADAVETPVYLYDIPARTQNHIEPGTALKLSEHGNIAGIK
                     DSGGAQDTLAAYLQVARDVPGFEVYSGPDHLVLWSLQNGAAGCISGLGNAMPDVLAGI
                     LSAFNAGDIAEAERQQSIYTAFRTELYALGFPPALVKRALYLQDSSVGASRQPALLPN
                     DEQDAKIREILVRFSVPMPL"
     misc_feature    441477..442346
                     /locus_tag="Smed_3989"
                     /note="Dihydrodipicolinate synthase/N-acetylneuraminate
                     lyase [Amino acid transport and metabolism / Cell envelope
                     biogenesis, outer membrane]; Region: DapA; COG0329"
                     /db_xref="CDD:223406"
     misc_feature    441492..442337
                     /locus_tag="Smed_3989"
                     /note="Dihydrodipicolinate synthase family; Region:
                     DHDPS-like; cd00408"
                     /db_xref="CDD:188630"
     misc_feature    order(441498..441500,441591..441593,441600..441608,
                     441870..441872,441954..441956)
                     /locus_tag="Smed_3989"
                     /note="inhibitor site; inhibition site"
                     /db_xref="CDD:188630"
     misc_feature    order(441591..441593,441600..441608,441870..441872,
                     441954..441956,442086..442088)
                     /locus_tag="Smed_3989"
                     /note="active site"
                     /db_xref="CDD:188630"
     misc_feature    order(441603..441605,441618..441623,441714..441719,
                     441789..441794,441813..441815,441825..441827,
                     442284..442289)
                     /locus_tag="Smed_3989"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188630"
     misc_feature    441954..441956
                     /locus_tag="Smed_3989"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188630"
     gene            complement(442397..443644)
                     /locus_tag="Smed_3990"
                     /db_xref="GeneID:5317916"
     CDS             complement(442397..443644)
                     /locus_tag="Smed_3990"
                     /note="PFAM: monooxygenase FAD-binding;
                     KEGG: msm:MSMEG_5719 oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding monooxygenase"
                     /protein_id="YP_001312731.1"
                     /db_xref="GI:150376135"
                     /db_xref="InterPro:IPR002938"
                     /db_xref="InterPro:IPR003042"
                     /db_xref="GeneID:5317916"
                     /translation="MRGKDILISGSGIAGLVLAWWLGRYGFRPTIVEKSTGLRRGGHA
                     VDLWGTALDVLEWMGLLAELEERRTRNDRGVMITPGLRPREIELNRISGQFASKQIEI
                     MRGELVGILGRSLSAGGDFMFGNSISGMDEHAGGVNVTFESGDSRDFELVIGADGQHS
                     NVRHIAFGEEDRFSRNLGGYVCGYTVADDHKLGEGVHRYVVPNKTVVVFPIRHSGDAA
                     VIFLFRPTRPLGLQHDDVKGQIKALQTTFGGESWEVAHLLDRLTGAKDFYFESLDQIT
                     MQSWHRARIALVGDAAYCPAPAVGGGTSLAVIGAYTLARELAEAKGDYRWALQSYHNA
                     TRDLVHQSRVIGPALFESLVPSSRISIYLGMLLLPLVTRLPGALRRNVPLLPRRAVRA
                     MRAVSEAPVRHGGLPESHESLSI"
     misc_feature    complement(442556..443635)
                     /locus_tag="Smed_3990"
                     /note="hypothetical protein; Provisional; Region:
                     PRK07588"
                     /db_xref="CDD:169028"
     misc_feature    complement(442652..443629)
                     /locus_tag="Smed_3990"
                     /note="ubiquinone biosynthesis hydroxylase family protein;
                     Provisional; Region: PRK07608; cl17314"
                     /db_xref="CDD:247868"
     gene            443809..444924
                     /locus_tag="Smed_3991"
                     /db_xref="GeneID:5317917"
     CDS             443809..444924
                     /locus_tag="Smed_3991"
                     /note="PFAM: secretion protein HlyD family protein;
                     KEGG: mag:amb3998 multidrug resistance efflux pump"
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD family protein"
                     /protein_id="YP_001312732.1"
                     /db_xref="GI:150376136"
                     /db_xref="InterPro:IPR006143"
                     /db_xref="GeneID:5317917"
                     /translation="MKRKIKGVASAATALLVFGVGAYFGRAWWQEFRMHERTDNAYVR
                     ADITAISPKVAGYVSTVLVDDNQVVEAGAILLRIDDDDYLAQRDRAAASVAQAEAAVG
                     NLTRRKSLQLANIREAEAMIDVARADLELSRRELSRATRLVDQGWTAQRNHDTATAKA
                     QSARATLVRAEAAAAAARAQLAVLDSESPQISARLAEARANLRLAEIALSETVIRAPV
                     SGVVGNRKVREGEYVRPGSVLLSVVPLDGIWVVANLKETQLARVMPGQRAEIRVDGYS
                     TTVIEGRVDSLAPASGAAFSLLPPDNATGNFIKVVQRVPVKIRLEPDHAFQGRLVPGL
                     SVDVAIHLAPEPERPPSQSNPVAAGRPTSSLTARREP"
     misc_feature    443809..444849
                     /locus_tag="Smed_3991"
                     /note="Multidrug resistance efflux pump [Defense
                     mechanisms]; Region: EmrA; COG1566"
                     /db_xref="CDD:224482"
     sig_peptide     443809..443886
                     /locus_tag="Smed_3991"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.997) with cleavage site probability 0.432 at
                     residue 26"
     misc_feature    443953..>444057
                     /locus_tag="Smed_3991"
                     /note="Biotin-lipoyl like; Region: Biotin_lipoyl_2;
                     pfam13533"
                     /db_xref="CDD:205711"
     misc_feature    444445..444783
                     /locus_tag="Smed_3991"
                     /note="HlyD family secretion protein; Region: HlyD_3;
                     pfam13437"
                     /db_xref="CDD:222128"
     gene            444921..446582
                     /locus_tag="Smed_3992"
                     /db_xref="GeneID:5317918"
     CDS             444921..446582
                     /locus_tag="Smed_3992"
                     /note="TIGRFAM: drug resistance transporter, EmrB/QacA
                     subfamily;
                     PFAM: major facilitator superfamily MFS_1;
                     KEGG: sme:SMb20698 putative transport protein, similar to
                     E. coli multidrug resistance protein EmrB"
                     /codon_start=1
                     /transl_table=11
                     /product="EmrB/QacA family drug resistance transporter"
                     /protein_id="YP_001312733.1"
                     /db_xref="GI:150376137"
                     /db_xref="InterPro:IPR004638"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5317918"
                     /translation="MTRFAATRHLRTAERDEPKASLRPWLVLVFLSIAATMDAVNSTV
                     LVVTRGHLMGGTHATPDEIAWINMTYLAAKLTALPASAWMMSCASPSRLLAGAIAALI
                     ASSLGCSATDDLGWLIGWRVLQGAAGATLLVVGQTLLFSMFPRSRQGIVQGLFAFATI
                     MAPTTLTPSLQGWIADTHSWSWLFAANVPLGTAGLFAAFLAADGQTTVRLVRRLDGVG
                     LVLFALFATAFVFVTQEGSRYNWFDEPEIIEYFALGSAAILAFMAWQFTKQGRDPLLD
                     FVIFRDEHFTFGFVVSFVAGCALFGSAFVIPAFATGVLDFPPAYAGFVLLPGGPLVCV
                     GLLAAGGLIDARGLDPAKPIPLGIVCFMAAMWALSGSTSGSGLSDLIPPIMLRGLGLG
                     LLFVSLTLLTLRDLGPEMIAQGVALFNLGRQMGGQFGIAWLSTILDNQNAQNRTVLSQ
                     YLAPGEHAVTERQDAVANYLTSRGYFPEEAGTAATAVIQKAFAQQVATLSFNACFLAI
                     ALLFIAAVPVLIATKLTLGRLVGRHGNLKQGPACLENTNERTSDL"
     misc_feature    444996..446282
                     /locus_tag="Smed_3992"
                     /note="drug resistance transporter, EmrB/QacA subfamily;
                     Region: efflux_EmrB; TIGR00711"
                     /db_xref="CDD:129794"
     misc_feature    445002..>445487
                     /locus_tag="Smed_3992"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    order(445044..445046,445053..445061,445065..445070,
                     445119..445121,445128..445133,445140..445142,
                     445152..445157,445161..445166,445302..445307,
                     445314..445319,445326..445331,445338..445340,
                     445374..445379,445386..445391,445407..445409)
                     /locus_tag="Smed_3992"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            446560..447726
                     /locus_tag="Smed_3993"
                     /db_xref="GeneID:5319240"
     CDS             446560..447726
                     /locus_tag="Smed_3993"
                     /note="PFAM: adenylyl cyclase class-3/4/guanylyl cyclase;
                     KEGG: ret:RHE_CH01194 probable adenylate cyclase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenylate/guanylate cyclase"
                     /protein_id="YP_001312734.1"
                     /db_xref="GI:150376138"
                     /db_xref="InterPro:IPR001054"
                     /db_xref="GeneID:5319240"
                     /translation="MSGQAISKLIEWLAGDDCHRADDGGLAEGLGQRLRAHGLPLDRL
                     TLHLRTLHPEIFGRSVAWAPSEPVEVREREHGFDRTAGFAGNPIRNAMETGEPVMVRI
                     GASNRPLWVDSDLFRDRGLVEFYIMPLRNADGTAGAASFATTQPSGFTDLHRAAIDRI
                     APALRNACELRTLRRIEHTLLDTYIGASPARRVLAGGVRRGQVEKLEAALMLCDLRGF
                     TELSNQLSAERVLELLNGYFDQVVPAITQAGGEVIKFMGDAALAFFDLQDPATSCNAA
                     LASAFDALKRLQCCSPRGVRLHAGIALHYGQAAYGNIGASQRLDFTLIGTDVNLVSRI
                     QGVCSATGHRLILSERCARLLHPDCSKSIGRHRLRGFPEHATLYVPASHPASKN"
     misc_feature    447178..447699
                     /locus_tag="Smed_3993"
                     /note="cyclase homology domain; Region: CHD; cd07302"
                     /db_xref="CDD:143636"
     misc_feature    447178..447699
                     /locus_tag="Smed_3993"
                     /note="Adenylate cyclase, family 3 (some proteins contain
                     HAMP domain) [Signal transduction mechanisms]; Region:
                     CyaA; COG2114"
                     /db_xref="CDD:225025"
     misc_feature    order(447193..447195,447199..447216,447319..447321,
                     447325..447333,447340..447342,447523..447531,
                     447541..447546,447553..447558,447664..447666)
                     /locus_tag="Smed_3993"
                     /note="nucleotidyl binding site; other site"
                     /db_xref="CDD:143636"
     misc_feature    order(447199..447201,447331..447333)
                     /locus_tag="Smed_3993"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143636"
     misc_feature    order(447214..447216,447250..447252,447259..447264,
                     447271..447273,447283..447285,447319..447324,
                     447484..447486,447493..447495,447526..447537,
                     447544..447546,447664..447666)
                     /locus_tag="Smed_3993"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143636"
     gene            complement(447776..448453)
                     /locus_tag="Smed_3994"
                     /db_xref="GeneID:5319241"
     CDS             complement(447776..448453)
                     /locus_tag="Smed_3994"
                     /note="PFAM: regulatory protein TetR;
                     KEGG: cvi:CV0711 probable transcriptional regulator, TetR
                     family"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_001312735.1"
                     /db_xref="GI:150376139"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="GeneID:5319241"
                     /translation="MAEEEFAEDEDDQEAASGRSGKRDARREEFLRAATEVFLSSGFS
                     GASVDSIIAKAGGSKRTIYSYFGKKDQLFTTVIKEITGRVMGPFPAANIAGADLDTVL
                     YRSGSHYLDAVMSPEALQLYRIVVGEGARFPGVARAFFENGPGRASAALASILEEGAD
                     NWGIPKRSAAKLAEHFIGMIRDDLHLKVVLGLCDPPTPAEARSSVRDAVDVFVYGIRK
                     TELTRSR"
     misc_feature    complement(447824..448399)
                     /locus_tag="Smed_3994"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    complement(448235..448363)
                     /locus_tag="Smed_3994"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:201228"
     misc_feature    complement(447815..447937)
                     /locus_tag="Smed_3994"
                     /note="AefR-like transcriptional repressor, C-terminal
                     region; Region: TetR_C_7; pfam14246"
                     /db_xref="CDD:206414"
     gene            complement(448573..449088)
                     /locus_tag="Smed_3995"
                     /db_xref="GeneID:5319242"
     CDS             complement(448573..449088)
                     /locus_tag="Smed_3995"
                     /note="KEGG: sme:SMb20139 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312736.1"
                     /db_xref="GI:150376140"
                     /db_xref="GeneID:5319242"
                     /translation="MLLKGWPALDNTRQGNGEFPAAAGILLGLGLGGFFDGIVLHQVL
                     QWHHMLSSAGFPPDSLENLKLNTFFDGLFHAATYIFVVLGVVVLWRSAHRRRLHWSAR
                     LMAGSFLMGFGAFNLVEGMVNHQLLGLHHVNETVPRDQWVYWDIGFLLWGAVMLIAGW
                     ALYRSGRRASG"
     misc_feature    complement(448576..449064)
                     /locus_tag="Smed_3995"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG4329"
                     /db_xref="CDD:226779"
     gene            complement(449108..449998)
                     /locus_tag="Smed_3996"
                     /db_xref="GeneID:5319243"
     CDS             complement(449108..449998)
                     /locus_tag="Smed_3996"
                     /note="PFAM: beta-lactamase domain protein;
                     KEGG: mes:Meso_3529 beta-lactamase-like"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase domain-containing protein"
                     /protein_id="YP_001312737.1"
                     /db_xref="GI:150376141"
                     /db_xref="InterPro:IPR001279"
                     /db_xref="GeneID:5319243"
                     /translation="MAQIPLGPSAVADKPQSDAARDDGTQEIARDLAYRRLAIVNVIF
                     FGEPGCGDRGWVLIDAGVVGTRALIKQAAAERFGSDARPAAIVMTHGHFDHIGALEDL
                     ADEWDVPVFAHPLEQPYLDGRAAYPPPDSSVGGGLMSLLSPLFPRGPVNVGRWLEPLP
                     ADGSVPHMPGWRWLHTPGHTPGHVSLWREADRIVVAGDAFITTRQESAYAVAVQSPEM
                     HGPPMYYTVDWAKARMSVEALASFRPELAVTGHGPAMRGQEMRMALAELARDFDHLAV
                     PPEGKYVENPVDTDSAYRAP"
     misc_feature    complement(449246..449848)
                     /locus_tag="Smed_3996"
                     /note="Metallo-beta-lactamase superfamily; Region:
                     Lactamase_B; smart00849"
                     /db_xref="CDD:214854"
     gene            450483..451409
                     /locus_tag="Smed_3997"
                     /db_xref="GeneID:5319244"
     CDS             450483..451409
                     /locus_tag="Smed_3997"
                     /note="PFAM: amidohydrolase 2;
                     KEGG: sme:SMb20138 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase 2"
                     /protein_id="YP_001312738.1"
                     /db_xref="GI:150376142"
                     /db_xref="InterPro:IPR006992"
                     /db_xref="GeneID:5319244"
                     /translation="MIIDISCYPTKLVDLAWRHDGEPFTGERLLKMMDGPYYVNGKPR
                     RIDKAFIQPPQGNTIYTDGYGDLTGKAAIRDYMSYTVELVQKYPDRFIGCFVYNPRYG
                     TQNGAEEIEHHAKEYGFKMVQLQANMHAYRPDRALDWLRPAMRKCADLGLIVKVHTGD
                     GPYSIPTEFYPIIREFPSVNFVLGHFGVQTGGVYVFEPFQMAMDAPNIYVESGWCLQS
                     RIVEFAKELPKHKLLFGTDTPPNEPGMWLRLLEVLCHEPPQGLNLDEDTLEDYLGNNI
                     GRMIGLDPTPPPRSVEEAQARLKGAHASLQPA"
     misc_feature    450483..451337
                     /locus_tag="Smed_3997"
                     /note="Predicted metal-dependent hydrolase of the
                     TIM-barrel fold [General function prediction only];
                     Region: COG2159"
                     /db_xref="CDD:225070"
     gene            451449..452381
                     /locus_tag="Smed_3998"
                     /db_xref="GeneID:5319245"
     CDS             451449..452381
                     /locus_tag="Smed_3998"
                     /note="PFAM: amidohydrolase 2;
                     KEGG: sme:SMb20137 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase 2"
                     /protein_id="YP_001312739.1"
                     /db_xref="GI:150376143"
                     /db_xref="InterPro:IPR006992"
                     /db_xref="GeneID:5319245"
                     /translation="MIIDTHLHPTNLVDEAWRHTGTPFNGERMLKLMDGPYMINGKPR
                     RIDMGFIQPPPGNTGYRDGNRMGREGIRDYMAYIAELCQKYPDRFIGNFNYNPRWGPE
                     NGAAELEFHVKEYGFKMLKLHANMHGYRPDRALDWLRPAMKKCAELGVVVLIHTGDGP
                     YTIPTMFYPIIREFPMVNFIIGHFGIQTGGNYSFESFWMAMDTPNVYCESGWCFQSRI
                     VEFAKELPKHKIVFGTDSPPNEPGMWLRELEVLCHEPPHGLGLSEDDLEGYLGNNIAK
                     LVGIDPTPPPRNLEEAKARLTDTYAGLRREPAPA"
     misc_feature    451455..452279
                     /locus_tag="Smed_3998"
                     /note="Superfamily of metallo-dependent hydrolases (also
                     called amidohydrolase superfamily) is a large group of
                     proteins that show conservation in their 3-dimensional
                     fold (TIM barrel) and in details of their active site. The
                     vast majority of the members have a...; Region:
                     metallo-dependent_hydrolases; cd01292"
                     /db_xref="CDD:238617"
     misc_feature    order(451464..451466,451470..451472,451911..451913,
                     451995..451997,452151..452153)
                     /locus_tag="Smed_3998"
                     /note="active site"
                     /db_xref="CDD:238617"
     gene            452531..453904
                     /locus_tag="Smed_3999"
                     /db_xref="GeneID:5319246"
     CDS             452531..453904
                     /locus_tag="Smed_3999"
                     /note="TIGRFAM: UbiD family decarboxylase;
                     PFAM: Carboxylyase-related protein;
                     KEGG: sme:SMb20136 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="YP_001312740.1"
                     /db_xref="GI:150376144"
                     /db_xref="InterPro:IPR002830"
                     /db_xref="GeneID:5319246"
                     /translation="MEFGSQDVRYFLREYQKAYPEDVLTIEDHITDDQDATAFIWRLN
                     QQGKAPLLHFRNVEGIACEVIANTFGSRERIARMFGTSQDRLHEAYQARSRKALPPRL
                     LDSGPVTECVEEGDIDLNTLPMLKHFATDRAKYITSGIIIAEHPETGAGNLSYHRAMI
                     HSKNELATSLHSRGHLWRLLNMAKDRGEKLRVAMVIGAHPLFMIAASARLAFGEDERD
                     VAGGLLGEPLEVVRTPRYGIRVPAYAEMVLEGVIEPEAQVAEGPFGEFTGYSSDRSTN
                     NLFRVETFLRRKDAILVSVAGGNSSEHLNLGRVPREAEMVEKLKQRFPSVTAVHYPAS
                     GTHFHAYIALNQTRPGEARQIMLGLLGWDAYLKTVIAVDADVDITQDSEVLWAMSAHF
                     QPHRDVVIIEGLPGNALDPSATGIGTTSRMGLDATRGPDFHGVLARIDDAAFGRVSSI
                     LAKLARP"
     misc_feature    452537..453901
                     /locus_tag="Smed_3999"
                     /note="3-polyprenyl-4-hydroxybenzoate decarboxylase and
                     related decarboxylases [Coenzyme metabolism]; Region:
                     UbiD; COG0043"
                     /db_xref="CDD:223121"
     gene            453934..454566
                     /locus_tag="Smed_4000"
                     /db_xref="GeneID:5319247"
     CDS             453934..454566
                     /locus_tag="Smed_4000"
                     /note="TIGRFAM: 3-octaprenyl-4-hydroxybenzoate
                     carboxy-lyase;
                     PFAM: flavoprotein;
                     KEGG: sme:SMb20135 putative 3-octaprenyl-4-hydroxybenzoate
                     carboxy-lyase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="3-octaprenyl-4-hydroxybenzoate carboxy-lyase"
                     /protein_id="YP_001312741.1"
                     /db_xref="GI:150376145"
                     /db_xref="InterPro:IPR003382"
                     /db_xref="InterPro:IPR004507"
                     /db_xref="GeneID:5319247"
                     /translation="MKADREQRKRIIVGISGASGVIYGIRLLEILRDLDIETHLVMSR
                     AAQITLAMETDFKVAEVEALACHVHSNKDIGASCSSGSFRTLGMIVAPCSVKTLSEIA
                     TGMTSGLLSRAADVTLKERRRLVLMLRETPLHLGHIRSMAQVTEAGAIICPPVPAFYA
                     RPQTLDEMVNHTVARVLDLFDIDTGLAHRWSGRRAVVLPNRFEDADAKTR"
     misc_feature    454045..454518
                     /locus_tag="Smed_4000"
                     /note="3-polyprenyl-4-hydroxybenzoate decarboxylase
                     [Coenzyme metabolism]; Region: UbiX; COG0163"
                     /db_xref="CDD:223241"
     misc_feature    <454045..454344
                     /locus_tag="Smed_4000"
                     /note="Flavoprotein; Region: Flavoprotein; pfam02441"
                     /db_xref="CDD:217035"
     gene            454646..456037
                     /locus_tag="Smed_4001"
                     /db_xref="GeneID:5319248"
     CDS             454646..456037
                     /locus_tag="Smed_4001"
                     /note="TIGRFAM: uracil-xanthine permease;
                     PFAM: Xanthine/uracil/vitamin C permease;
                     KEGG: sme:SMb20134 putative permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease"
                     /protein_id="YP_001312742.1"
                     /db_xref="GI:150376146"
                     /db_xref="InterPro:IPR006042"
                     /db_xref="InterPro:IPR006043"
                     /db_xref="GeneID:5319248"
                     /translation="MNKDSKCDAIEEMFPAPKLAALGLQHVLVMYAGAIAVPLIIGSA
                     LNLSKDQIAMLISADLFCCGIVTLIQCLGIWNIGARLPIMMGIGFTAVPPIIATGTDP
                     DLGMPGVLGAVIASGVFTLLAAPYFSRWVRFFPAVVTGTVMLVIGLSLMRVGVNWAAG
                     GQPMIKGPDGLIPNPAYGQPFALAVAAIVLVSILLMTRFLKGFLANLAVLFGIGIGFA
                     IAVAFGKVDFQGVADASWVTVVTPFAFGMPVFDLWASVALCTVMIVMMIEATGQILAV
                     GDMAGRTITEADLARGLRTDGIGNVIGGIFNTFTYTTYAQNVGLLQITGVMSRWAVAA
                     GGIVLILLGCLPKIAFITASIPSYVVGGAAIVMFGMVSATGVKILSRVDFVANRRNLY
                     IVAVSVGLAMIPVVADKIFAQLPEFIDRFFHSGVLVGTFSAVLLNLLFNGIPRREEVQ
                     PVLLGEGAVRHPG"
     misc_feature    454712..455968
                     /locus_tag="Smed_4001"
                     /note="xanthine permease; Region: pbuX; TIGR03173"
                     /db_xref="CDD:234136"
     gene            complement(456248..457288)
                     /locus_tag="Smed_4002"
                     /db_xref="GeneID:5319249"
     CDS             complement(456248..457288)
                     /locus_tag="Smed_4002"
                     /note="PFAM: cobalamin synthesis protein P47K; cobalamin
                     synthesis CobW domain protein;
                     KEGG: sme:SMb20133 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin synthesis protein P47K"
                     /protein_id="YP_001312743.1"
                     /db_xref="GI:150376147"
                     /db_xref="InterPro:IPR003495"
                     /db_xref="InterPro:IPR011629"
                     /db_xref="GeneID:5319249"
                     /translation="MQTNHLQDSKIPVTILTGFLGAGKTTLLNHILTERHGHRIAVIE
                     NEFGEVDVDSDLVLASEEEIYQMKNGCICCFVDVRNDLIEVLQKLLARKDKFDHILVE
                     TSGLADPTPVATAFFIDDEIGKHVTLDGIVTLVDAKHIGQHIEDPVLDGRDNQAVDQI
                     VAADRIIINKIDLVSDGEIAPLERDMRKLNQTAEIVRSSYGKVDLSSILGISGFAPSY
                     VAERAKLLDLDHHHHGHHHHHHHDATVSSESFVFDRPFDQHRLTEYLSDLLREKGDDI
                     FRTKGIIAITGDPRFFVLQAVHKLMDFRPDHVWGKDMPYSKLVFIGRNLDRAVLEEGL
                     KRCLTPAGETVY"
     misc_feature    complement(456275..457258)
                     /locus_tag="Smed_4002"
                     /note="Putative GTPases (G3E family) [General function
                     prediction only]; Region: COG0523"
                     /db_xref="CDD:223597"
     misc_feature    complement(456770..457255)
                     /locus_tag="Smed_4002"
                     /note="The function of this protein family is unkown. The
                     amino acid sequence of YjiA protein in E. coli contains
                     several conserved motifs that characterizes it as a P-loop
                     GTPase. YijA gene is among the genes significantly induced
                     in response to DNA-damage...; Region: CobW_like; cd03112"
                     /db_xref="CDD:239386"
     misc_feature    complement(457214..457237)
                     /locus_tag="Smed_4002"
                     /note="P-loop, Walker A motif; other site"
                     /db_xref="CDD:239386"
     misc_feature    complement(456773..456784)
                     /locus_tag="Smed_4002"
                     /note="Base recognition motif; other site"
                     /db_xref="CDD:239386"
     misc_feature    complement(456275..456556)
                     /locus_tag="Smed_4002"
                     /note="Cobalamin synthesis protein cobW C-terminal domain;
                     Region: CobW_C; pfam07683"
                     /db_xref="CDD:219512"
     gene            complement(457288..459606)
                     /locus_tag="Smed_4003"
                     /db_xref="GeneID:5318283"
     CDS             complement(457288..459606)
                     /locus_tag="Smed_4003"
                     /note="PFAM: aldehyde oxidase and xanthine dehydrogenase
                     a/b hammerhead; aldehyde oxidase and xanthine
                     dehydrogenase molybdopterin binding;
                     KEGG: sme:SMb20132 probable aldehyde oxidase and xanthine
                     dehydrogenase family protein transmembrane"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidase and xanthine dehydrogenase
                     molybdopterin binding protein"
                     /protein_id="YP_001312744.1"
                     /db_xref="GI:150376148"
                     /db_xref="InterPro:IPR000674"
                     /db_xref="InterPro:IPR000706"
                     /db_xref="InterPro:IPR008274"
                     /db_xref="GeneID:5318283"
                     /translation="MNTHERIDRDLSERDFTVVGKSVKRSDTLEKVTGAARYAGDVAL
                     PGMLYAKMKRSNIAHARIKSIDTSKALALQGVKAVLTHQDVPRVLHAGSPHPRSASVT
                     KDQYILDERVRYWGEGVAAVAAVSEEIAERAVALIEVEYDPLPGLFTIEAASDPAAPP
                     IHENGLGQNYVLPPVFVTRGDVDKGFGEADLVIEREYDLGRPTPAYMEPNVCVSQWDG
                     NGKLTMWTSTQSAFMVRGTLAEVLGVPLNKVRVIVDHMGGGFGAKQDLFQNEFLCALL
                     ARRTGRPVKMEFSRKETFVGGRSRHPGKIWLKQGFTRDGRIVAREARVTFNSGAYGSH
                     GPGVTNVGTAALTSLYRCENVRLEGRCIYTNSPIAGAFRGYGVVQTYYALDLMMDEAA
                     EKLGFDPAEFKLMNAVREGDMAPSGHPIVGHGLVDCIRRVMEETNWHELRRREKPETV
                     KRRGIGIGCEMHGSSAYPGIKEQGNAIVKMNEDGTVTLITGTAGLGTGAHTALSQIVA
                     EELGVPFEAVSVVQGDTDMVPWDIGAFASHTTYLGGRAAQLAAADVRRQVLEHAAPLL
                     KAEPGDLAIRDGFVVVANGSNQSLRLSEAVGPQRGMPAVQLVGVGTYMPTKSYSFAAH
                     FAEVEVDTETGEVAVLEVVPVHEIGRVIHPIAAAGQIEGGIQQGIGHTLSEDYVIDLT
                     DGRSLNPSFVDYKMPLSMDMPSIRTIIIETAPDPGGPYGAKGVGEDPIIAIGPAIANA
                     IYDAIGVRFHHYPITPEQVLNALKTKANETRQ"
     misc_feature    complement(457315..459567)
                     /locus_tag="Smed_4003"
                     /note="Aerobic-type carbon monoxide dehydrogenase, large
                     subunit CoxL/CutL homologs [Energy production and
                     conversion]; Region: CoxL; COG1529"
                     /db_xref="CDD:224446"
     misc_feature    complement(459172..459510)
                     /locus_tag="Smed_4003"
                     /note="Aldehyde oxidase and xanthine dehydrogenase, a/b
                     hammerhead domain; Region: Ald_Xan_dh_C; smart01008"
                     /db_xref="CDD:214971"
     misc_feature    complement(457498..459102)
                     /locus_tag="Smed_4003"
                     /note="Molybdopterin-binding domain of aldehyde
                     dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738"
                     /db_xref="CDD:217210"
     gene            complement(459603..460088)
                     /locus_tag="Smed_4004"
                     /db_xref="GeneID:5318284"
     CDS             complement(459603..460088)
                     /locus_tag="Smed_4004"
                     /note="PFAM: ferredoxin; [2Fe-2S]-binding domain protein;
                     KEGG: sme:SMb20131 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="YP_001312745.1"
                     /db_xref="GI:150376149"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR002888"
                     /db_xref="InterPro:IPR006058"
                     /db_xref="GeneID:5318284"
                     /translation="MNRLVSMTVNGEPCELSVALNRTLLDALRNEGSLTGTKKGCDVG
                     DCGACTVIMDGRPVNACLVLAAEAEGAAIETIEGLQPAYDKPHALQQKFMEFGGAQCG
                     FCTPGIIMMAKALLDENPDPSEDEIRFALAGNICRCTGYTKIIDAVRATAEELRRAGT
                     L"
     misc_feature    complement(459618..460085)
                     /locus_tag="Smed_4004"
                     /note="Aerobic-type carbon monoxide dehydrogenase, small
                     subunit CoxS/CutS homologs [Energy production and
                     conversion]; Region: CoxS; COG2080"
                     /db_xref="CDD:224991"
     misc_feature    complement(<459927..460076)
                     /locus_tag="Smed_4004"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(459942..459953,459957..459959,
                     459966..459968,459975..459980))
                     /locus_tag="Smed_4004"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(459942..459944,459951..459953,
                     459966..459968))
                     /locus_tag="Smed_4004"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     misc_feature    complement(459639..459839)
                     /locus_tag="Smed_4004"
                     /note="[2Fe-2S] binding domain; Region: Fer2_2; pfam01799"
                     /db_xref="CDD:201981"
     gene            complement(460085..460948)
                     /locus_tag="Smed_4005"
                     /db_xref="GeneID:5318285"
     CDS             complement(460085..460948)
                     /locus_tag="Smed_4005"
                     /note="PFAM: molybdopterin dehydrogenase FAD-binding; CO
                     dehydrogenase flavoprotein domain protein;
                     KEGG: sme:SMb20130 putative dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding molybdopterin dehydrogenase"
                     /protein_id="YP_001312746.1"
                     /db_xref="GI:150376150"
                     /db_xref="InterPro:IPR002346"
                     /db_xref="InterPro:IPR005107"
                     /db_xref="GeneID:5318285"
                     /translation="MKPFEYYEPATLAEASELLRRLGKDASIIAGGTDLLVELKEDLR
                     SAHHIVNIKKIPGLTDFAYDPANGLRFGALVTVREIETSPAVNGNYPNLAKAVSLLGS
                     IQVRNRATVVGNICRASPSADTIPPLIADGASLSVYSGGTERSIPLDEFFTGPGRTVL
                     VPGDIVTGISMPAPRPTSGRAYIKHGRRKAMELATVGVAVSMEHVAGQCSDIRIALGA
                     VAPTVIRARRTEDLLRGRMIDAALLAEAAESAMQEATPIGNVRASAAYRRDMVGVLTR
                     RAIGYAMGGVQ"
     misc_feature    complement(460088..460948)
                     /locus_tag="Smed_4005"
                     /note="Aerobic-type carbon monoxide dehydrogenase, middle
                     subunit CoxM/CutM homologs [Energy production and
                     conversion]; Region: CoxM; COG1319"
                     /db_xref="CDD:224238"
     misc_feature    complement(460112..460408)
                     /locus_tag="Smed_4005"
                     /note="CO dehydrogenase flavoprotein C-terminal domain;
                     Region: CO_deh_flav_C; pfam03450"
                     /db_xref="CDD:217566"
     gene            complement(461001..461780)
                     /locus_tag="Smed_4006"
                     /db_xref="GeneID:5318286"
     CDS             complement(461001..461780)
                     /locus_tag="Smed_4006"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20129 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312747.1"
                     /db_xref="GI:150376151"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318286"
                     /translation="MAVSPFFRSQKDRAPAGAAMSGPEAEHRVVQVIVEAIMDHRVAP
                     GARLIERELAIASGASRSAIRNGLMRLAHAGLVELSPNKGASIAMCSPDEARQIFDAR
                     IVIETAAVKKLAGTIGEGELERLRAFVEDEREAYERGRMEDARHLSRRFHVLLAEMAG
                     NDVLTGVIRDLINRQPLLSWSRPETEPRFCGNHAHSEIVEAIASRDGERAAHLNMEHL
                     RALERELGAERAAAMQELRSAQAADGPDGNARQADESPVVD"
     misc_feature    complement(461130..461738)
                     /locus_tag="Smed_4006"
                     /note="Transcriptional regulators [Transcription]; Region:
                     GntR; COG1802"
                     /db_xref="CDD:224715"
     misc_feature    complement(461526..461702)
                     /locus_tag="Smed_4006"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cl17414"
                     /db_xref="CDD:247968"
     misc_feature    complement(order(461526..461537,461541..461546,
                     461574..461576,461583..461588,461592..461606,
                     461628..461633))
                     /locus_tag="Smed_4006"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(461130..461492)
                     /locus_tag="Smed_4006"
                     /note="FCD domain; Region: FCD; pfam07729"
                     /db_xref="CDD:219539"
     gene            462221..463519
                     /locus_tag="Smed_4007"
                     /db_xref="GeneID:5318287"
     CDS             462221..463519
                     /locus_tag="Smed_4007"
                     /note="PFAM: amidohydrolase; Amidohydrolase 3;
                     KEGG: sme:SMb20128 putative deaminase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase 3"
                     /protein_id="YP_001312748.1"
                     /db_xref="GI:150376152"
                     /db_xref="InterPro:IPR006680"
                     /db_xref="InterPro:IPR013108"
                     /db_xref="GeneID:5318287"
                     /translation="MHTVIGARQGGARRALLLRGCRIAGEIAAEAGRDILVGENGRIA
                     RIGSRLDVGPDVAVVEVRGALISPGFVDVHQHLDKTGVLRFTPNPSGTLQGAREAFAE
                     YARKAPEEDVTRRAARTMARCLGRGTTAIRSHINVDKDAGFNGINALARLRSEWADRL
                     TLQIVAFMTPHPNQDLAWLESNIDAAVEQADAVGGTPAVAEDPIRYLDILFAAAKRHG
                     RPIDLHLDEHLNPERPLFDAVFERVRKFGLQGRTVLGHASVLSALPRTEFERIRDRMI
                     DLDIAVVTLPAANLYLQGRSHDMLPPRGLTRVAELIRSGVAIATASDNIQDPFVPTGS
                     GDMLEIARWTLLAGHLRGDELATAYDMITKIPARMMNLGADYGIREGAWADLVISDCE
                     DVSALVSAGPDCMQVLAKGRPIAAPAFPAMAAICALENVP"
     misc_feature    462302..463456
                     /locus_tag="Smed_4007"
                     /note="cytosine deaminase; Provisional; Region: PRK05985"
                     /db_xref="CDD:180337"
     misc_feature    462320..463456
                     /locus_tag="Smed_4007"
                     /note="Bacterial cytosine deaminase and related
                     metal-dependent hydrolases. Cytosine deaminases (CDs)
                     catalyze the deamination of cytosine, producing uracil and
                     ammonia. They play an important role in pyrimidine
                     salvage. CDs are present in prokaryotes and fungi; Region:
                     Bact_CD; cd01293"
                     /db_xref="CDD:238618"
     misc_feature    order(462440..462442,462446..462448,462890..462892,
                     462899..462901,462986..462988,463187..463189)
                     /locus_tag="Smed_4007"
                     /note="active site"
                     /db_xref="CDD:238618"
     gene            463573..464556
                     /locus_tag="Smed_4008"
                     /db_xref="GeneID:5318288"
     CDS             463573..464556
                     /locus_tag="Smed_4008"
                     /note="PFAM: basic membrane lipoprotein;
                     KEGG: sme:SMb20127 putative simple sugar transport system
                     substrate-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="basic membrane lipoprotein"
                     /protein_id="YP_001312749.1"
                     /db_xref="GI:150376153"
                     /db_xref="InterPro:IPR003760"
                     /db_xref="GeneID:5318288"
                     /translation="MMITRRGCLASAVAAAALIAAGSALAEGAPFKMGLLVPGSVSEE
                     GWNRIGFNALKGVEAELGAEVSYVELQQNPASFEKAFHDFASQGYNVILGHGFEFQDA
                     ALAVAPEYPDTVFLISSSYISEGNVIGLNTDTSQPFYLMGVIAAKTGKKAGLVGGMEI
                     PPIKEAFEGFTNGVRSVAPDFPISEVYIGNFTDATATKEASLSLISQGADFVLPNASG
                     ATVGGFQAAAESGENVKTFSIFSDFTSVAPKNILGLYIADYARGVIRIVGDIKNGKKP
                     TTNVEFGLKDADVMQFTYNDQAANPVTENVRKYVDEVKAKIAAGEIKTRQK"
     sig_peptide     463573..463653
                     /locus_tag="Smed_4008"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.994 at
                     residue 27"
     misc_feature    463660..464553
                     /locus_tag="Smed_4008"
                     /note="Uncharacterized ABC-type transport system,
                     periplasmic component/surface lipoprotein [General
                     function prediction only]; Region: Med; COG1744"
                     /db_xref="CDD:224658"
     misc_feature    463666..464439
                     /locus_tag="Smed_4008"
                     /note="Periplasmic binding domain of the basic membrane
                     lipoprotein Med in Bacillus and its close homologs from
                     other bacteria and Archaea; Region: PBP1_BmpA_Med_like;
                     cd06353"
                     /db_xref="CDD:107348"
     misc_feature    order(463684..463689,463711..463713,463927..463929,
                     464059..464061,464143..464145,464290..464292,
                     464341..464343)
                     /locus_tag="Smed_4008"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107348"
     gene            464717..465814
                     /locus_tag="Smed_4009"
                     /db_xref="GeneID:5318289"
     CDS             464717..465814
                     /locus_tag="Smed_4009"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20126 putative sugar ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="YP_001312750.1"
                     /db_xref="GI:150376154"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318289"
                     /translation="MANSESGQPLAVAPQAYGALWRGLLRPLRTVAQPAAAVALALAC
                     GAALLAFNGYDARAVIDVMVLGVFQDTRSIAEILLKATPLILIGVGLCVAFRCSIWNI
                     GAEGQFYAGAAAATAIGVSFNGLGAWLYVPLVMLAGALAGAAWAAIAGLLKIYFRASE
                     IVTTIMLNYIALIMTSYLVTGPLRDAAAAYPQSARLVQEAWMPRILPPTRLHIGILVA
                     LVLAVVMYVFLFRSARGYALRVVGISPDAARYAGISVPRNIMISICLSGSMAGLAGAF
                     EIAGVTRRLFQSISPGYGFEGIAVALLANNNPIGAIFSGLLFAVLRSGSELMQITAQI
                     PQVLVLVIQGIVILSVVGFAVLRIPSLRPSE"
     misc_feature    464933..465688
                     /locus_tag="Smed_4009"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    464957..465712
                     /locus_tag="Smed_4009"
                     /note="Transmembrane subunit (TM) of Treponema pallidum
                     (Tp) RbsC-1, RbsC-2 and related proteins. This is a
                     functionally uncharacterized subgroup of TMs which belong
                     to a larger group of TMs of Periplasmic Binding Protein
                     (PBP)-dependent ATP-Binding Cassette; Region:
                     TM_PBP1_transp_TpRbsC_like; cd06580"
                     /db_xref="CDD:119322"
     misc_feature    465452..465508
                     /locus_tag="Smed_4009"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119322"
     gene            465823..466755
                     /locus_tag="Smed_4010"
                     /db_xref="GeneID:5318290"
     CDS             465823..466755
                     /locus_tag="Smed_4010"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20125 putative sugar ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="YP_001312751.1"
                     /db_xref="GI:150376155"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318290"
                     /translation="MEDLASLSFLAATIAASWRLAAPLIFASIGEVFSERAGVLNIGL
                     EGTMLAGAFAGFAAAFTSGSILFGVAAAIAAGVLVGLLFAFFTITIKADQIVVGAAIN
                     LLGLGLTAFLFRSYFPSAGKGIDIAKPVHLPWLSDLPFFGEALFRQNAFVYSTLPVAA
                     LAVFVLYRTSFGLTLRAVGEHPKAVDVAGRSVALYRYGAVLICSALAALGGAFLTLAH
                     SNQFVEGISSGRGFIALAVVVFARWSPIGAFVVSLLFGVFYALQLQLQAQPVHFLPYQ
                     LFQALPYLMTIAALIFVRNRVGTPSMLGVAYKKS"
     sig_peptide     465823..465888
                     /locus_tag="Smed_4010"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.804) with cleavage site probability 0.740 at
                     residue 22"
     misc_feature    465877..466692
                     /locus_tag="Smed_4010"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    465883..466692
                     /locus_tag="Smed_4010"
                     /note="Transmembrane subunit (TM) of Treponema pallidum
                     (Tp) RbsC-1, RbsC-2 and related proteins. This is a
                     functionally uncharacterized subgroup of TMs which belong
                     to a larger group of TMs of Periplasmic Binding Protein
                     (PBP)-dependent ATP-Binding Cassette; Region:
                     TM_PBP1_transp_TpRbsC_like; cd06580"
                     /db_xref="CDD:119322"
     misc_feature    466369..466425
                     /locus_tag="Smed_4010"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119322"
     gene            466766..468292
                     /locus_tag="Smed_4011"
                     /db_xref="GeneID:5318291"
     CDS             466766..468292
                     /locus_tag="Smed_4011"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20124 putative sugar ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312752.1"
                     /db_xref="GI:150376156"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318291"
                     /translation="MSGRQLLLMDGIHKRFGPLIVSAGVTLDIEENEIHALLGENGAG
                     KTVLMSILCGVLSPDEGQIIFKGQALKPGSPRQAIKHRIGMVHQHFMLVPNLTVAENY
                     VLGQGSPFSVIRDMKTVHARIVELSDRYGLGVKPDALISDLSVGEQQRVEILKVLYHG
                     VELLILDEPTAVLTPQETDRLLHLLRRLVEDGKTVIFISHKLDEVIRVSDRVSVMRDA
                     KVVRTVKTSETNARELARMMVGRDVLMDLPRAPIEPGRVVLSVEHLNCDGESGLPALH
                     GVSFQVRANEIVGIAGVSGNGQSELALALTGLLPIASGSVTLEGAELVGRSSHDINQM
                     PIAHIPEDRHRMGIVLPLPLTENVILQRFDKPPFSSRGMLDMSEITRQTRDLMRRFQV
                     KASGPGDRIQNLSGGNQQKLVVGRELDRRFDFLLINQLTRGIDIGATELVMHKILEQR
                     SAGKAILLISTELEELFTLCDRILVMYEGRLVGEMPPDRGRLEEIGLLMAGKSPMSAA
                     "
     misc_feature    466772..468268
                     /locus_tag="Smed_4011"
                     /note="ABC-type uncharacterized transport systems, ATPase
                     components [General function prediction only]; Region:
                     COG3845"
                     /db_xref="CDD:226364"
     misc_feature    466790..467434
                     /locus_tag="Smed_4011"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    466880..466903
                     /locus_tag="Smed_4011"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(466889..466894,466898..466906,467027..467029,
                     467264..467269,467363..467365)
                     /locus_tag="Smed_4011"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    467018..467029
                     /locus_tag="Smed_4011"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(467051..467062,467204..467221)
                     /locus_tag="Smed_4011"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    467252..467269
                     /locus_tag="Smed_4011"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    467276..467287
                     /locus_tag="Smed_4011"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    467351..467371
                     /locus_tag="Smed_4011"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    467528..468208
                     /locus_tag="Smed_4011"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            468423..469319
                     /locus_tag="Smed_4012"
                     /db_xref="GeneID:5318292"
     CDS             468423..469319
                     /locus_tag="Smed_4012"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb20123 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001312753.1"
                     /db_xref="GI:150376157"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318292"
                     /translation="MNVTLRQLQAFIAVAELGRFHLAADHLGLTQSAISILIRDLEAV
                     LKHRLFDRHTRMVSLTTAGAEFLPQARKIMSDLEIAVTNVHELANLQRGRVTIAAAIV
                     LAATLLPPVIARFVKRYPDIQVQVRDMPEEEIRSALKRNEADLGIGTVSADDPEIQAS
                     VLMRDQLTLICRSDHRFARAPQVSWANLAGEALIGLAKDNPLRGLVDHALIASGVEVK
                     TRYEVRFSTTAISMVAEGLGIAILPENSRQLTTNVDVRIVDLVDPVISRNISILQYRQ
                     PMLSPAAAKMKEFLMGASRKPS"
     misc_feature    468432..469316
                     /locus_tag="Smed_4012"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    468435..468611
                     /locus_tag="Smed_4012"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    468756..469292
                     /locus_tag="Smed_4012"
                     /note="TThe C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator,
                     contains the type 2 periplasmic binding fold; Region:
                     PBP2_LTTR_like_4; cd08440"
                     /db_xref="CDD:176131"
     misc_feature    order(468756..468761,468768..468770,468780..468782,
                     468786..468806,469080..469097,469113..469118,
                     469122..469127)
                     /locus_tag="Smed_4012"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176131"
     gene            complement(469325..470272)
                     /locus_tag="Smed_4013"
                     /db_xref="GeneID:5318822"
     CDS             complement(469325..470272)
                     /locus_tag="Smed_4013"
                     /note="PFAM: PfkB domain protein;
                     KEGG: dra:DR1525 carbohydrate kinase, PfkB family"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase-like domain-containing protein"
                     /protein_id="YP_001312754.1"
                     /db_xref="GI:150376158"
                     /db_xref="InterPro:IPR002139"
                     /db_xref="InterPro:IPR002173"
                     /db_xref="InterPro:IPR011611"
                     /db_xref="GeneID:5318822"
                     /translation="MSVIVLLGDINVDLALEISTYPPEGGEAIATAQRMFLGGSATNT
                     AVALSRSGHRCRLIGRVGDDGWGKQALRDLRGEGIDTTWIGRDSAEPTQINVVTVGST
                     GERTMFAYRGANAQLSPAAIDAAAFDAAELFHLSGYAFLQSPQSEAADHAIGLAVARN
                     IPITLDIPGGIVSRLASRVRTILPRLDTIVLGDADLAPLADKPYGTSLEEAVRALLDL
                     GVERVAVKANEGRSLLCSAGVTESASWLPADAFDTTGAGDAFAAGHIHGRLTGMTGRE
                     CCRLANAFGALAVARRGAGLAMPAIDEALALLGASDGPS"
     misc_feature    complement(469337..470263)
                     /locus_tag="Smed_4013"
                     /note="Sugar kinases, ribokinase family [Carbohydrate
                     transport and metabolism]; Region: RbsK; COG0524"
                     /db_xref="CDD:223598"
     misc_feature    complement(469427..470263)
                     /locus_tag="Smed_4013"
                     /note="2-keto-3-deoxygluconate kinase (KdgK)
                     phosphorylates 2-keto-3-deoxygluconate (KDG) to form
                     2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the
                     common intermediate product, that allows organisms to
                     channel D-glucuronate and/or D-galacturinate into the...;
                     Region: KdgK; cd01166"
                     /db_xref="CDD:238571"
     misc_feature    complement(order(469499..469501,469508..469510,
                     469757..469759,469859..469861,469940..469942,
                     469946..469948,469988..469990,470144..470146,
                     470153..470158))
                     /locus_tag="Smed_4013"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238571"
     misc_feature    complement(order(469427..469429,469493..469495,
                     469502..469510,469535..469537,469580..469582,
                     469595..469597))
                     /locus_tag="Smed_4013"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238571"
     gene            complement(470282..471484)
                     /locus_tag="Smed_4014"
                     /db_xref="GeneID:5318823"
     CDS             complement(470282..471484)
                     /locus_tag="Smed_4014"
                     /EC_number="2.5.1.48"
                     /note="PFAM: aminotransferase class V; Cys/Met metabolism
                     pyridoxal-phosphate-dependent protein;
                     DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid
                     beta-eliminating lyase/threonine aldolase;
                     aminotransferase class I and II;
                     KEGG: ctc:CTC02530 Cys/Met metabolism lyase
                     (PLP-dependent)"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="YP_001312755.1"
                     /db_xref="GI:150376159"
                     /db_xref="InterPro:IPR000192"
                     /db_xref="InterPro:IPR000277"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="InterPro:IPR001597"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="GeneID:5318823"
                     /translation="MSPKELDFASQAVFYTPEEHSQSISYPIYMSANFQYDGDIYDQI
                     VAGARKEVNIYSRCGNPTEYKFEEHIAKLTGGTACLATASGMAAISHALFGILKAGDH
                     IVADLTTYSSTHEFFDHRAQDFGLKVSLVDCTDVRAVENALTEETKVLYVEAIANPTM
                     KVPPLKALVELAHARGIVVICDNTFASPAVCRPHDFGVDVVVESATKFIGGHNDAVGG
                     VITLKSDILPPDWLEDVRWNTLNKLGAPLSPFNAWLLLRGAQTLALRLEKQCANALAL
                     AKHLEAHPRVRRVFYPGLPSHPNYASAKEQLRGGGAMLSFQVDDEASGVRLLKRLQLC
                     SFAASLGGLRTTTQVPATMAFLDIPSQEREAMGVVDGLVRFSVGIEHIDDIIADVDSA
                     IDQMHMEI"
     misc_feature    complement(470342..471442)
                     /locus_tag="Smed_4014"
                     /note="Cys/Met metabolism PLP-dependent enzyme; Region:
                     Cys_Met_Meta_PP; pfam01053"
                     /db_xref="CDD:216267"
     misc_feature    complement(470342..471418)
                     /locus_tag="Smed_4014"
                     /note="CGS_like: Cystathionine gamma-synthase is a PLP
                     dependent enzyme and catalyzes the committed step of
                     methionine biosynthesis. This pathway is unique to
                     microorganisms and plants, rendering the enzyme an
                     attractive target for the development of...; Region:
                     CGS_like; cd00614"
                     /db_xref="CDD:99738"
     misc_feature    complement(order(470498..470500,470732..470737,
                     470741..470743,470774..470776,470837..470839,
                     470843..470845,470867..470869,471131..471133,
                     471140..471142,471155..471157,471224..471229,
                     471233..471238,471314..471316,471320..471322,
                     471377..471382,471386..471397))
                     /locus_tag="Smed_4014"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99738"
     misc_feature    complement(order(470837..470839,470864..470869,
                     470873..470875,470939..470941,471026..471028,
                     471155..471157,471227..471235))
                     /locus_tag="Smed_4014"
                     /note="substrate-cofactor binding pocket; other site"
                     /db_xref="CDD:99738"
     misc_feature    complement(order(470864..470869,470873..470875,
                     470930..470932,470939..470941,471155..471157,
                     471227..471235))
                     /locus_tag="Smed_4014"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99738"
     misc_feature    complement(470864..470866)
                     /locus_tag="Smed_4014"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99738"
     gene            complement(471527..472363)
                     /locus_tag="Smed_4015"
                     /db_xref="GeneID:5318824"
     CDS             complement(471527..472363)
                     /locus_tag="Smed_4015"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: oih:OB0776 sugar ABC transporter permease"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312756.1"
                     /db_xref="GI:150376160"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318824"
                     /translation="MTAVRRWNLTSTIVLAVLTAHVLMVIFPFFWMIYSTFKTNREFM
                     RSVWSLPKSFSLDAYVGAWSGGALGGYAVNSLLIMAGATLITVVLATLAGFALAAYRP
                     RWIPAVELSMTAAMAIPAYVALVPLVVMLRGAGLLDTHLGVILPTAAFNVPVSIFIMQ
                     AFFNTLPRDLFDAARMDGASEWKIFLRVALPIARPAMFTVAIVNMIWVWNDFLFPVVF
                     INSPSRKTLPVGLTDFVGEHITNYPVMLAAILIAAIAPLVLFVFFERQITAALIGGAV
                     KG"
     misc_feature    complement(471533..472363)
                     /locus_tag="Smed_4015"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    complement(471695..472150)
                     /locus_tag="Smed_4015"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(471713..471718,471725..471736,
                     471755..471757,471764..471769,471809..471811,
                     471860..471862,471869..471874,471884..471886,
                     471890..471895,471902..471904,471908..471910,
                     471914..471916,471980..471982,471986..471991,
                     471998..472027,472031..472042,472070..472072,
                     472085..472090,472097..472102))
                     /locus_tag="Smed_4015"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(471719..471736,471980..472024))
                     /locus_tag="Smed_4015"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(471716..471718,471920..471922,
                     471980..471982))
                     /locus_tag="Smed_4015"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(471788..471790,471800..471805,
                     471821..471859))
                     /locus_tag="Smed_4015"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(472360..473268)
                     /locus_tag="Smed_4016"
                     /db_xref="GeneID:5318825"
     CDS             complement(472360..473268)
                     /locus_tag="Smed_4016"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: oih:OB0775 sugar ABC transporter permease"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001312757.1"
                     /db_xref="GI:150376161"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318825"
                     /translation="MSADTSFAKRSNRAAILFLSPALLFVFAFVAYPVAYAGWLSLFR
                     WDGASMPVFLGAGNFVRLAGDAIFWQALFRNILVALSAIVLQVFLALAIAYCLVRIVP
                     AFSRIFLFFYLVPVMVSEICIGLLWRFMYNPYFGLVNAGLSGIGLGGLKRGWLGESET
                     AFTAVVVVMSFTYLGLYVLLFVAAVRNVPESVYEAAEIDGAGDFRKFFSITVPMVWDA
                     VRANSLLAIIGSLKTFSLVFVLTNGGPNHASEVVSTYLYKMGFGSFEMGYAAAIGFAQ
                     MVLTALGAWIAFRYMKRIGAGAGAWS"
     sig_peptide     complement(473155..473268)
                     /locus_tag="Smed_4016"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.998) with cleavage site probability 0.762 at
                     residue 38"
     misc_feature    complement(472429..473055)
                     /locus_tag="Smed_4016"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(472429..472431,472438..472443,
                     472450..472455,472459..472464,472471..472476,
                     472504..472509,472552..472557,472564..472575,
                     472594..472596,472603..472608,472648..472650,
                     472699..472701,472708..472713,472723..472725,
                     472729..472734,472741..472743,472747..472749,
                     472753..472758,472885..472887,472891..472896,
                     472903..472932,472936..472947,472975..472977,
                     472990..472995,473002..473007))
                     /locus_tag="Smed_4016"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(472558..472575,472885..472929))
                     /locus_tag="Smed_4016"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(472474..472476,472504..472506,
                     472513..472515,472555..472557,472771..472773,
                     472885..472887))
                     /locus_tag="Smed_4016"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(472627..472629,472639..472644,
                     472660..472698))
                     /locus_tag="Smed_4016"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(473294..474601)
                     /locus_tag="Smed_4017"
                     /db_xref="GeneID:5318826"
     CDS             complement(473294..474601)
                     /locus_tag="Smed_4017"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: bcl:ABC0436 sugar ABC transporter substrate-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312758.1"
                     /db_xref="GI:150376162"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5318826"
                     /translation="MWHHFMGGSAWPQGNGEDIVRLKRLLIAGAAAALAAMPASAGEL
                     SFWHAYAGQQDKVEFIDFALGEFAKAHPEVKLEVVAAEQSAYKTKLNTAMASGNPPDV
                     FYTLPGGFLNAFVKGGQMYALDEELARDGWRDSFLESAISQTSKDGHTYAVPVDVDSV
                     VFWYDKARFAENGWTVPKTYEELLALAEKVKGEGLVPFSLGNKDSWPATFWFQYLEMR
                     LKGSGVVSAFVNGDPDATLGAEATKAMEKLAELAKQEYFPIGFNGMSDQEANMLFLNG
                     QAAMMLNGTWQIGASADAPEGFELGYFAFPAVAGGAGDQSDVLAGVAASFGVSQKAEN
                     KADAVTLLKFLTSREVMTKYVELRKTMVTVKDATTETAAGPVLYDISNKLMKAAGHLD
                     PFYDTAMPPAATNIYYTSLQGVLDGSLPPADAAKRIEDALRAK"
     sig_peptide     complement(474476..474601)
                     /locus_tag="Smed_4017"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.961) with cleavage site probability 0.959 at
                     residue 42"
     misc_feature    complement(473300..474475)
                     /locus_tag="Smed_4017"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     misc_feature    complement(473549..474451)
                     /locus_tag="Smed_4017"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     gene            474685..475539
                     /locus_tag="Smed_4018"
                     /db_xref="GeneID:5318827"
     CDS             474685..475539
                     /locus_tag="Smed_4018"
                     /note="PFAM: helix-turn-helix protein RpiR; sugar
                     isomerase (SIS);
                     KEGG: pmu:PM1714 hypothetical HI0143"
                     /codon_start=1
                     /transl_table=11
                     /product="RpiR family transcriptional regulator"
                     /protein_id="YP_001312759.1"
                     /db_xref="GI:150376163"
                     /db_xref="InterPro:IPR000281"
                     /db_xref="InterPro:IPR001347"
                     /db_xref="GeneID:5318827"
                     /translation="MTVDLRGPSVPASSRLRSVLPKLSDAERRVALWMLKNVDLSIRQ
                     SMSAIAQATDVSDTTVLRMCRTAGFEGFTDLKLALAQEPREAIEHSSGEPEASALQAA
                     GRLFRAITQALNDTFGVLDEATFAKALDLVANAKHIMVGGVGGSGIVAQAFYQRCIRL
                     GLRCDAPIDSQLQIMHAALTGPGDLVVAISYSGITSDPVLVLQEAKARGASTLCITGN
                     SSSALARLADVVLVSVSHEQGSEPMAAQIAQMTLVDALYAALVARNPEPAQLTEERMV
                     NAILPKSI"
     misc_feature    474724..474930
                     /locus_tag="Smed_4018"
                     /note="Helix-turn-helix domain, rpiR family; Region:
                     HTH_6; pfam01418"
                     /db_xref="CDD:201784"
     misc_feature    474727..475521
                     /locus_tag="Smed_4018"
                     /note="Transcriptional regulators [Transcription]; Region:
                     RpiR; COG1737"
                     /db_xref="CDD:224651"
     misc_feature    475051..475461
                     /locus_tag="Smed_4018"
                     /note="RpiR-like protein. RpiR contains a SIS (Sugar
                     ISomerase) domain, which is found in many phosphosugar
                     isomerases and phosphosugar binding proteins. In E. coli,
                     rpiR negatively regulates the expression of rpiB gene.
                     Both rpiB and rpiA are ribose phosphate...; Region:
                     SIS_RpiR; cd05013"
                     /db_xref="CDD:240144"
     misc_feature    order(475120..475122,475252..475254)
                     /locus_tag="Smed_4018"
                     /note="putative active site [active]"
                     /db_xref="CDD:240144"
     gene            475540..476235
                     /locus_tag="Smed_4019"
                     /db_xref="GeneID:5318828"
     CDS             475540..476235
                     /locus_tag="Smed_4019"
                     /note="PFAM: N-(5'phosphoribosyl)anthranilate isomerase
                     (PRAI);
                     KEGG: bja:bll8013 putative phosphoribosylanthranilate
                     isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="N-(5'phosphoribosyl)anthranilate isomerase"
                     /protein_id="YP_001312760.1"
                     /db_xref="GI:150376164"
                     /db_xref="InterPro:IPR001240"
                     /db_xref="GeneID:5318828"
                     /translation="MQTETALKIQIYTMQTAAEAVAAAAAGVDYLGVTPSNRGLPGEI
                     TFAKAREIVDALEGKAQRVALSVESNLDDIAAMVEAVRPDVLHLCGDIALVTPEQVKV
                     LRSRLSAEHPALRILQAIPMTGPEALDQAAAFEPFVDMFILDSVAPHIGGIGAAGVTH
                     DWSLSREIVARSRLPVILAGGLRPDNVRAAIEAVRPWGVDSLTHTNRPLPEGGFRKDL
                     DKIAAFVEAARAT"
     misc_feature    475564..476223
                     /locus_tag="Smed_4019"
                     /note="Phosphoribosylanthranilate isomerase (PRAI)
                     catalyzes the fourth step of the tryptophan biosynthesis,
                     the conversion of N-(5&apos;- phosphoribosyl)-anthranilate
                     (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose
                     5-phosphate (CdRP). Most PRAIs are...; Region: PRAI;
                     cd00405"
                     /db_xref="CDD:238237"
     misc_feature    order(475567..475569,475573..475575,475798..475800,
                     475804..475806,475969..475971,476137..476139,
                     476143..476148)
                     /locus_tag="Smed_4019"
                     /note="active site"
                     /db_xref="CDD:238237"
     gene            476548..477567
                     /locus_tag="Smed_4020"
                     /db_xref="GeneID:5318829"
     CDS             476548..477567
                     /locus_tag="Smed_4020"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb20117 hypothetical sugar transferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001312761.1"
                     /db_xref="GI:150376165"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318829"
                     /translation="MTEELVRQGHEVTLFASGDSMTSARLVPCSQMALRLNPAIQDPI
                     PYHMMLLEEVRRQAPAFDILHFHIDLLHFPLVRDLAGKTVTTLHGRLDLPDLQPFYAA
                     FPDVPLVSISHDQRRPMPPVNWIATVHHGLAPDVLPFTSPPKGDYLAFLGRISPEKRP
                     DRAIEIAARAGMPLKMAAKVDRVDEPYWLSEIEPLIRRYPNVEFIGEINEHQKAEFLG
                     NARALLFPIDWPEPFGLVMIEAMACGTPVIAFRCGSVPEIVDHGVSGFIVDSTEEALK
                     AVHGLDRVDRRMVRATFDRRFTAQRMANDYLDIYRALASGSQRVMPIHAANESNAGPG
                     SARVA"
     misc_feature    476551..477480
                     /locus_tag="Smed_4020"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. aviGT4 in Streptomyces
                     viridochromogenes has been shown to be involved in
                     biosynthesis of oligosaccharide antibiotic avilamycin A.
                     Inactivation of aviGT4 resulted in a mutant...; Region:
                     GT1_AviGT4_like; cd03802"
                     /db_xref="CDD:99975"
     misc_feature    476557..477498
                     /locus_tag="Smed_4020"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    order(476998..477006,477184..477186,477253..477255)
                     /locus_tag="Smed_4020"
                     /note="putative ADP-binding pocket [chemical binding];
                     other site"
                     /db_xref="CDD:99975"
     gene            477697..479901
                     /locus_tag="Smed_4021"
                     /db_xref="GeneID:5318830"
     CDS             477697..479901
                     /locus_tag="Smed_4021"
                     /note="PFAM: Amylo-alpha-16-glucosidase;
                     KEGG: sme:SMb20116 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="amylo-alpha-16-glucosidase"
                     /protein_id="YP_001312762.1"
                     /db_xref="GI:150376166"
                     /db_xref="InterPro:IPR010401"
                     /db_xref="GeneID:5318830"
                     /translation="MGTNLSGAAAEAAPDVTSADELGPAAVSRYERSSRSLKHGDTFA
                     VFDHNGDAFSSPSNPEGIFHRDTRHLSQFVLRLNGARSLLLSSTLRDDNATLDCDLTN
                     PALVLDTGGEVLKHDLIHVRRTRFLWQEACYERLVLRNFDEAPRRLQVELSFAADFAD
                     LFEVRGTPRRRRGTHHNALVGNGRVVLAYDGLDGQTRSTTLRFDPEPQRLTGQEASFV
                     VELAPNQAQSIFIEIVCNSLEDNPHPPAFNFFLALRDARRALRYSASRAAAVVTSNAV
                     FNEAVRRSVADLYMLLTETPEGPYPYAGIPWFSTVFGRDALITALETLWLDPAIAKGV
                     LRHLAANQATDFDPVADAEPGKILHEMRYGEMAELGEVPFRRYYGSVDSTPLFIMLAG
                     AYLDRTGDTDTVRGLWPNIVAALDWIDRFGDRDGDGFVEYGSRTAKGLVNQCWKDSHD
                     SIFHADGRLAKGPVATAEVQAYIFGAWRAAARLSRKLGHAEDALRLEQRAEDLRIRFD
                     AAFFDEELGTYSLALDGDKNPCRVRSSNAGHALFTGIALPERAGRVVSTLMAQSSFCG
                     WGVRTIAASEARYNPMSYHNGSVWPHDNALIAAGFVRYGFQAEAASIFEGLFAASTYI
                     DLRRLPELFCGFSRQRARGPTFYPVSCVPQAWAAAAPLYLLQSMIGLGFDAEKSQVML
                     TEPTLPPFLDEVVLKRLRVGPGIVDIALRRSRSQVVVDVLERKGGVKVLTTH"
     misc_feature    477721..479823
                     /locus_tag="Smed_4021"
                     /note="Glycogen debranching enzyme [Carbohydrate transport
                     and metabolism]; Region: GDB1; COG3408"
                     /db_xref="CDD:225942"
     misc_feature    478603..479673
                     /locus_tag="Smed_4021"
                     /note="Amylo-alpha-1,6-glucosidase; Region: GDE_C;
                     pfam06202"
                     /db_xref="CDD:114894"
     gene            480030..481751
                     /locus_tag="Smed_4022"
                     /db_xref="GeneID:5318322"
     CDS             480030..481751
                     /locus_tag="Smed_4022"
                     /EC_number="4.2.1.9"
                     /note="catalyzes the formation of 3-methyl-2-oxobutanoate
                     from 2,3,-dihydroxy-3-methylbutanoate"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="YP_001312763.1"
                     /db_xref="GI:150376167"
                     /db_xref="InterPro:IPR000581"
                     /db_xref="GeneID:5318322"
                     /translation="MTSTLRSARWFAPDDLRSSGHRSRLMQMGYDARDWGEKPIIAIL
                     NTWSDLNPCHAHFKHRIEDVKRGVLQAGGFPVELPVQSLSESSLKPTTMLYRNFLAME
                     AEELLRGHPIDGTVLMGGCDKTTPALVMGAISAGLPMIFLPAGPMLRGHYKGEHLGSG
                     SDAWKYWDERRAGTITDEQWIGVEEGIARSYGHCMTFGTASTMTAIAESLGLTLPGAS
                     SIPAADANHIRMSTRCGRRIVEMVHEKLAPDKIITEKSVANASAVAMATGCSTNAVVH
                     LIAMARRAGVPLTLEDLDRISRTTPVIANIRPSGKQYLMEDFYYAGGLRALMAEMKEL
                     LHLDAMTVSGFPLGATLEGAEVHNSDVIRPLSNPIYHEGSLAVLKGNLAPDGCVVKPS
                     ACEERLRVHEGPALVFDSYPEMKAAIDDEDLDVTPDHVLILRNAGPKGGPGMPEWGML
                     PIPKKILKQGCRDMLRISDARMSGTSYGACILHVAPESHIGGPLSLVRTGDVIRVDVP
                     NRTIDMLVDEETLAKRRAEWKPPADRYERGYGWMFSRHIKQANEGCDFDFLETAFGSA
                     VGEPDIF"
     misc_feature    480039..481748
                     /locus_tag="Smed_4022"
                     /note="dihydroxy-acid dehydratase; Provisional; Region:
                     PRK13016"
                     /db_xref="CDD:237271"
     gene            481779..482504
                     /locus_tag="Smed_4023"
                     /db_xref="GeneID:5318323"
     CDS             481779..482504
                     /locus_tag="Smed_4023"
                     /note="PFAM: Dimethylmenaquinone methyltransferase;
                     KEGG: sme:SMb20114 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312764.1"
                     /db_xref="GI:150376168"
                     /db_xref="InterPro:IPR005493"
                     /db_xref="GeneID:5318323"
                     /translation="MSVYSLSKEARRKFEGVSCATLCTALFKRGLRNQFIQDVRPVSP
                     KATNMVGQAFTLRYIPAREDLNQLSVFQNPDHPQRAAVEQCPPGFVMVMDSRKDPRAA
                     SAGSILVSRLMVRGVAGVVTDGGFRDSPEIGELDIPAYHCRPSAPTNLTLHQALDINI
                     PIGCGDVAVWPGDVVIGDREGVVVVPAHLAEEIADEAVEMTAFEDFVTEEVLKGRSII
                     GLYPATQERTKADFAAWRQSKGR"
     misc_feature    481779..482501
                     /locus_tag="Smed_4023"
                     /note="hypothetical protein; Validated; Region: PRK08245"
                     /db_xref="CDD:236200"
     gene            482507..483439
                     /locus_tag="Smed_4024"
                     /db_xref="GeneID:5318324"
     CDS             482507..483439
                     /locus_tag="Smed_4024"
                     /note="PFAM: D-isomer specific 2-hydroxyacid dehydrogenase
                     catalytic region; D-isomer specific 2-hydroxyacid
                     dehydrogenase NAD-binding;
                     KEGG: sme:SMb20113 putative dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding D-isomer specific 2-hydroxyacid
                     dehydrogenase"
                     /protein_id="YP_001312765.1"
                     /db_xref="GI:150376169"
                     /db_xref="InterPro:IPR006139"
                     /db_xref="InterPro:IPR006140"
                     /db_xref="GeneID:5318324"
                     /translation="MAMLRDVTVLQAAELPEKTDRELREIFNVLRLPTDEAAIGPLLA
                     EHGTRIRGVAVRHAHIDAAMLDRLPALEIISSYSAGLDGIDVESAHARGVVVRNTSRI
                     LAEDVADLALALSISATRGLMRGHDFVREGRWGQIAFPLGRSLRSMKTGIIGLGHIGS
                     AVAARLRAIGAATAYSGPRRKPVDLPYFDSVEGLAAWADLLVVTCPAGPETIGLVNHA
                     VLANLGPEGYLVNVSRGTIVDEQALISALAGNRIAGAALDVFENEPFVPDTLRNDPRV
                     VLSPHMGSGTHETRQQMGDSMVAALVEHFESRSA"
     misc_feature    482522..483436
                     /locus_tag="Smed_4024"
                     /note="Lactate dehydrogenase and related dehydrogenases
                     [Energy production and conversion / Coenzyme metabolism /
                     General function prediction only]; Region: LdhA; COG1052"
                     /db_xref="CDD:223980"
     misc_feature    482525..483424
                     /locus_tag="Smed_4024"
                     /note="Hydroxy(phenyl)pyruvate Reductase,
                     D-isomer-specific 2-hydroxyacid-related dehydrogenase;
                     Region: HPPR; cd12156"
                     /db_xref="CDD:240633"
     misc_feature    order(482675..482677,482738..482746,482813..482815,
                     483206..483208,483347..483349)
                     /locus_tag="Smed_4024"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:240633"
     misc_feature    order(482741..482746,482825..482827,482966..482980,
                     483032..483043,483116..483124,483137..483139,
                     483200..483208,483278..483280,483347..483349,
                     483353..483358)
                     /locus_tag="Smed_4024"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:240633"
     misc_feature    order(483206..483208,483293..483295,483347..483349)
                     /locus_tag="Smed_4024"
                     /note="catalytic site [active]"
                     /db_xref="CDD:240633"
     gene            complement(483569..484393)
                     /locus_tag="Smed_4025"
                     /db_xref="GeneID:5318325"
     CDS             complement(483569..484393)
                     /locus_tag="Smed_4025"
                     /note="PFAM: protein of unknown function DUF6
                     transmembrane;
                     KEGG: sme:SMb20112 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312766.1"
                     /db_xref="GI:150376170"
                     /db_xref="InterPro:IPR000620"
                     /db_xref="GeneID:5318325"
                     /translation="MGANSLVAAMDSVIVRFVAGEVHPIGIVFFRNLASLGALYLLIR
                     SRGFVVERTMSFHVHAIRAIIKLLALLAAFIAVTQIPLASATAIAFTMPLFVAFGSVL
                     FLGERFSSGRALSLAGGFAGILIVVRPGAETFDTGAAWALASAVGLAIVALLMKVSAG
                     REDPVSIAWLNLLVTVPVAFLLALPFWQTPSLFSLFLMTLQGIGGLFAQLSFARAMKL
                     ADASLLVTVDFIRLPLALVIGLLFFGEPIRLDVVIGGAIILGAITLLFHREGRGTK"
     gene            complement(484435..486075)
                     /locus_tag="Smed_4026"
                     /db_xref="GeneID:5318326"
     CDS             complement(484435..486075)
                     /locus_tag="Smed_4026"
                     /note="PFAM: ABC transporter related;
                     Oligopeptide/dipeptide ABC transporter domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20111 putative oligopeptide ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312767.1"
                     /db_xref="GI:150376171"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013563"
                     /db_xref="GeneID:5318326"
                     /translation="MTGTHLLEVKDLTVDFLSLGGSFRATNGVSFHVDAGETLVILGE
                     SGSGKSVSASAIMGLIDTPPGDICAGSVAYRGRDLSSLSEGERRDLNGRKIAMIFQDP
                     LSHLNPVYTIGWQMEEVFSVHGVASGGVARQRAIDILRRVGIPEPEKRIDQYPHQFSG
                     GQRQRIMIGMAIALRPEILIADEPTTALDVSVQAQILELLKKLQAEDGLAIIMITHDL
                     EVAANMADRVIVMKSGRIVEEGEARAVFENPAHTYTRTLINALPHGDHEAPPKRGRPA
                     GKPILEVRNIDKFYTLSSGFFAKPARLHAVKKLSFDVAAGETIGIVGESGSGKSTVAR
                     VLLGLNEASGGEALFHGRDILKMDRKELLAFRRKVQMVFQDPYSSMNPRMTVLDIVSE
                     PWRIHKDILEKPRWRDRVTELLGLVGLNPEHAARYPHQFSGGQRQRIAIARALACDPE
                     LVVCDEAVSALDVSVQVQVIGLLAELRDRLGLAYIFITHDLPIVRHFADRIIVMKSGE
                     IVEHATTEEIFRSPQHAYTRQLINATPKPKWQTAADAA"
     misc_feature    complement(484465..486066)
                     /locus_tag="Smed_4026"
                     /note="ATPase components of various ABC-type transport
                     systems, contain duplicated ATPase [General function
                     prediction only]; Region: COG1123"
                     /db_xref="CDD:224048"
     misc_feature    complement(485356..486060)
                     /locus_tag="Smed_4026"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    complement(485926..485949)
                     /locus_tag="Smed_4026"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(order(485428..485430,485527..485532,
                     485776..485778,485923..485931,485935..485940))
                     /locus_tag="Smed_4026"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(485776..485787)
                     /locus_tag="Smed_4026"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(485575..485604)
                     /locus_tag="Smed_4026"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(485527..485544)
                     /locus_tag="Smed_4026"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(485509..485520)
                     /locus_tag="Smed_4026"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(485422..485442)
                     /locus_tag="Smed_4026"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(485203..485367)
                     /locus_tag="Smed_4026"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; pfam08352"
                     /db_xref="CDD:219806"
     misc_feature    complement(484537..485238)
                     /locus_tag="Smed_4026"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    complement(485086..485109)
                     /locus_tag="Smed_4026"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(order(484609..484611,484708..484713,
                     484954..484956,485083..485091,485095..485100))
                     /locus_tag="Smed_4026"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(484954..484965)
                     /locus_tag="Smed_4026"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(484756..484785)
                     /locus_tag="Smed_4026"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(484708..484725)
                     /locus_tag="Smed_4026"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(484690..484701)
                     /locus_tag="Smed_4026"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(484603..484623)
                     /locus_tag="Smed_4026"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(<484462..484554)
                     /locus_tag="Smed_4026"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     gene            complement(486072..487019)
                     /locus_tag="Smed_4027"
                     /db_xref="GeneID:5318327"
     CDS             complement(486072..487019)
                     /locus_tag="Smed_4027"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20110 putative oligopeptide ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312768.1"
                     /db_xref="GI:150376172"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318327"
                     /translation="MSATAMTTSADTPETKVSRFQVLRLISRDWLALAAVIFLLIVVG
                     CAVFGPWLVGDLIDKPNFRARNMAPFDLSQGWTYVLGADTLGRSLLARLVVGAQNTIG
                     IAFCAVLFSVVIGGMLGLIAGYSRGAAGTMIMRGADIVMSFPSLLLALIVLFSLGPSV
                     TNLVLVLAITRVPIYLRTTRAEVLEVRERMFVSAAVALGANHRRILFRHIAPMVLPTL
                     VTIGAIDFATVVLAESSLSFLGLGIQAPEFTWGAMVATGRGYLSTAWWIAFWPGLAIL
                     LTTLSLNILSSWWRTYADPQQRWRIELARSKKGIPEKRK"
     misc_feature    complement(486120..486887)
                     /locus_tag="Smed_4027"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppC; COG1173"
                     /db_xref="CDD:224094"
     misc_feature    complement(486228..486731)
                     /locus_tag="Smed_4027"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(486228..486233,486261..486266,
                     486306..486311,486318..486329,486348..486350,
                     486357..486362,486402..486404,486453..486455,
                     486462..486467,486477..486479,486483..486488,
                     486495..486497,486501..486503,486507..486512,
                     486561..486563,486567..486572,486579..486608,
                     486612..486623,486651..486653,486666..486671,
                     486678..486683))
                     /locus_tag="Smed_4027"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(486312..486329,486561..486605))
                     /locus_tag="Smed_4027"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(486231..486233,486261..486263,
                     486270..486272,486309..486311,486525..486527,
                     486561..486563))
                     /locus_tag="Smed_4027"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(486381..486383,486393..486398,
                     486414..486452))
                     /locus_tag="Smed_4027"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(487016..487939)
                     /locus_tag="Smed_4028"
                     /db_xref="GeneID:5318328"
     CDS             complement(487016..487939)
                     /locus_tag="Smed_4028"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20109 putative oligopeptide ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001312769.1"
                     /db_xref="GI:150376173"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318328"
                     /translation="MFAFILRRAGQSVIAVIGLLVLVFFLSRLTGDPAYLYLPLDSSE
                     AQRQAFSEAHGFNDPLVVQFGRYLVDLARFDFGDALSRNRPAMEVALEAFPQTLKLAA
                     IAIVLSLCLAVVVGSLAAARPGSLFDKLATTASLAGASAPDFWVAIVAILVFSVGLGL
                     LPTSGTGTALHWIMPIFVLTLRPFGLLVQVVRGTMMSALASPYVKTARAKGVNRSRIV
                     FRHALRNSLLPVITVAGDLAASLVNGAVVVETIFGWPGIGKLMIDAIVRRDFALIQAT
                     VLVTAIAIFVLNIAIDLVYARLDPRIRFETR"
     misc_feature    complement(487031..487939)
                     /locus_tag="Smed_4028"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppB; COG0601"
                     /db_xref="CDD:223674"
     sig_peptide     complement(487847..487939)
                     /locus_tag="Smed_4028"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.748) with cleavage site probability 0.517 at
                     residue 31"
     misc_feature    complement(487082..487660)
                     /locus_tag="Smed_4028"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(487082..487087,487094..487099,
                     487106..487111,487115..487120,487127..487132,
                     487160..487165,487190..487195,487202..487213,
                     487232..487234,487241..487246,487286..487288,
                     487337..487339,487346..487351,487361..487363,
                     487367..487372,487379..487381,487385..487387,
                     487391..487396,487487..487489,487493..487498,
                     487505..487534,487538..487549,487577..487579,
                     487595..487600,487607..487612))
                     /locus_tag="Smed_4028"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(487196..487213,487487..487531))
                     /locus_tag="Smed_4028"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(487130..487132,487160..487162,
                     487169..487171,487193..487195,487409..487411,
                     487487..487489))
                     /locus_tag="Smed_4028"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(487265..487267,487277..487282,
                     487298..487336))
                     /locus_tag="Smed_4028"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(488012..489520)
                     /locus_tag="Smed_4029"
                     /db_xref="GeneID:5318329"
     CDS             complement(488012..489520)
                     /locus_tag="Smed_4029"
                     /note="PFAM: extracellular solute-binding protein family
                     5;
                     KEGG: sme:SMb20108 putative ABC transporter periplasmic
                     oligopeptide-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312770.1"
                     /db_xref="GI:150376174"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="GeneID:5318329"
                     /translation="MIIRYCTGALALFAATLLAGAAIAAEGEVKIVLPEQPANLDPCR
                     SIRSDIGRIINSNITETLTVIDTEKGTVGPWLAEKWEQVDDLTWRVHLKSGVKFQDGV
                     EFNAEAVVKSINRLMNPNITCDSRSKFGDVKLTPKAVDAQTVEISSDSPVPIMPTLLG
                     TVQIVSPNMPFDKESNDPVGTGPYVVESKSNEQIVLKRHDAYWGAKPDVTRATYVWRS
                     ESAIRAAMVESGEADMTPSIAVQDATNAESDFAYLNSETTRMRIDAQIPPLDDVRIRK
                     ALNMAIDWDGMGEALFGKDVLRASQMVVPGVRGHNPDIKPWTYNPEEAMKLVEQAKAD
                     GAPVDKEIVLIGRNGFFPNSAESLEAIRSMWQEIGLNVSIRQLEAADWVRYLDKPFPE
                     GRGPTLFQQQHDNNTGDAGFTAPVMYLSEGQYSTIADKDLDAVLKKAMAATGDEREKL
                     FQEVFAKVHDEIVADVPMYHMIGYVRVGSRLDWKPDLKTNSEIALSEIHFKD"
     sig_peptide     complement(489446..489520)
                     /locus_tag="Smed_4029"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.992 at
                     residue 25"
     misc_feature    complement(488063..489442)
                     /locus_tag="Smed_4029"
                     /note="ABC-type dipeptide transport system, periplasmic
                     component [Amino acid transport and metabolism]; Region:
                     DdpA; COG0747"
                     /db_xref="CDD:223818"
     misc_feature    complement(488027..489439)
                     /locus_tag="Smed_4029"
                     /note="The substrate-binding component of an
                     uncharacterized ABC-type
                     nickel/dipeptide/oligopeptide-like import system contains
                     the type 2 periplasmic binding fold; Region:
                     PBP2_NikA_DppA_OppA_like_12; cd08491"
                     /db_xref="CDD:173856"
     gene            complement(489650..490606)
                     /locus_tag="Smed_4030"
                     /db_xref="GeneID:5318330"
     CDS             complement(489650..490606)
                     /locus_tag="Smed_4030"
                     /note="KEGG: sme:SMb20107 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312771.1"
                     /db_xref="GI:150376175"
                     /db_xref="GeneID:5318330"
                     /translation="MQIRLDARDYAASVVAVPPIALNADLTVNADANAAIIRHIEEGG
                     VGILLYGGNANLYHFGLEDYRAGMQAVIAAASPETRIITSIGPDFGKALAQAPIARDL
                     GLRNVMLLPTQFPADPAGVANGVRRLAAVLGHGLVLYLKRENYVDPDELGRLVSEGAV
                     DFVKYAVERPDPAQDAYLDAIIAAIGKDRMASGMGETPIHDHLGGRSLTTYTSGAVCI
                     APSAAMELLRLYKAGRGAEAFELSRPFLEFEKVRAELGGLQVLHDGMRLAGIADTGPL
                     MPMISNLNAEKLGPVGVAVKALQVAEADCLRRAGKPSVSALA"
     misc_feature    complement(489716..490567)
                     /locus_tag="Smed_4030"
                     /note="Dihydrodipicolinate synthase/N-acetylneuraminate
                     lyase [Amino acid transport and metabolism / Cell envelope
                     biogenesis, outer membrane]; Region: DapA; COG0329"
                     /db_xref="CDD:223406"
     misc_feature    complement(489770..490567)
                     /locus_tag="Smed_4030"
                     /note="Dihydrodipicolinate synthase family; Region:
                     DHDPS-like; cd00408"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(490115..490117,490190..490192,
                     490448..490456,490463..490465,490556..490558))
                     /locus_tag="Smed_4030"
                     /note="inhibitor site; inhibition site"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(489971..489973,490115..490117,
                     490190..490192,490448..490456,490463..490465))
                     /locus_tag="Smed_4030"
                     /note="active site"
                     /db_xref="CDD:188630"
     misc_feature    complement(order(489773..489778,490235..490237,
                     490247..490249,490268..490270,490337..490342,
                     490433..490438,490451..490453))
                     /locus_tag="Smed_4030"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188630"
     misc_feature    complement(490115..490117)
                     /locus_tag="Smed_4030"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188630"
     gene            complement(490674..491405)
                     /locus_tag="Smed_4031"
                     /db_xref="GeneID:5318331"
     CDS             complement(490674..491405)
                     /locus_tag="Smed_4031"
                     /note="PFAM: regulatory protein GntR HTH; protein of
                     unknown function UPF0074; GntR domain protein;
                     KEGG: sme:SMb20106 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312772.1"
                     /db_xref="GI:150376176"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR000944"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318331"
                     /translation="MPEKPLILESLAEARPSSYADQVYGRILHDILNGVFQPGARLPT
                     ENELAERFGVSRPVVREALARLRVDGLVEARRGSGTYVLSRPSQTLPELADLEDISRF
                     LRYQELRFHVEGQAAALAAERRTEKQLAAIVEAHETFAHEVGRGAFLPESDRRFHLAI
                     CEATGNEFFAKALEGPEVSLTSFMNVSLALTRSGSQARARRVIAEHAEIVEAIRTKDA
                     AWARVAMETHIIKARRRMTDGTIDS"
     misc_feature    complement(490686..491378)
                     /locus_tag="Smed_4031"
                     /note="Transcriptional regulators [Transcription]; Region:
                     FadR; COG2186"
                     /db_xref="CDD:225097"
     misc_feature    complement(491160..491348)
                     /locus_tag="Smed_4031"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(491166..491177,491181..491186,
                     491214..491216,491223..491228,491232..491246,
                     491268..491273,491277..491279,491346..491348))
                     /locus_tag="Smed_4031"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(490719..491087)
                     /locus_tag="Smed_4031"
                     /note="This entry represents the C-terminal ligand binding
                     domain of many members of the GntR family; Region: FCD;
                     smart00895"
                     /db_xref="CDD:214892"
     gene            491508..492212
                     /locus_tag="Smed_4032"
                     /db_xref="GeneID:5318332"
     CDS             491508..492212
                     /locus_tag="Smed_4032"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20105 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312773.1"
                     /db_xref="GI:150376177"
                     /db_xref="InterPro:IPR000485"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5318332"
                     /translation="MISEAPTAKHRTGLDRTRQIAPQIVEYLREKILALELAPGTALS
                     RVELQNQFGLSQTPVRDALMRLEEEGLVTVYPQYATLVSKIDINLARQTHLMRRAVEQ
                     EAVFNLAENANRRQIADRLRTANTNLKALASKEFADFLAADRAFHFIIFEEAGLEHIW
                     PIIRRHSGHIDRLRRLNLVNVGTKRVVDTHDMIIEGIEKGAPVDAAQAMKTHLSGTLS
                     MIDDIAARYPDYIELG"
     misc_feature    491574..492197
                     /locus_tag="Smed_4032"
                     /note="Transcriptional regulators [Transcription]; Region:
                     GntR; COG1802"
                     /db_xref="CDD:224715"
     misc_feature    491574..491756
                     /locus_tag="Smed_4032"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    order(491640..491645,491667..491681,491685..491690,
                     491697..491699,491727..491732,491736..491747)
                     /locus_tag="Smed_4032"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    491793..492146
                     /locus_tag="Smed_4032"
                     /note="FCD domain; Region: FCD; pfam07729"
                     /db_xref="CDD:219539"
     gene            complement(492310..494112)
                     /locus_tag="Smed_4033"
                     /db_xref="GeneID:5318333"
     CDS             complement(492310..494112)
                     /locus_tag="Smed_4033"
                     /note="KEGG: sme:SMb20103 putative monooxygenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative monooxygenase"
                     /protein_id="YP_001312774.1"
                     /db_xref="GI:150376178"
                     /db_xref="InterPro:IPR000103"
                     /db_xref="InterPro:IPR001100"
                     /db_xref="InterPro:IPR001327"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="GeneID:5318333"
                     /translation="MLEESPGTRIDIVLAKLGRALERGDIDAAVNLFQADCYWRDLVA
                     FTWNLKTMEGQDQIRDMLTSQLAAIKPARLRQDEMERPGDADGVTEGWFEFETEVARG
                     HGHIRLKNGLIWTLLTTMTELKGHEEPRGARRPLGAEHGHDPSRKTWKEKRETEAAEL
                     GYTSQPYVVIIGGGQGGIALGARLRQLGVPAIIIEKNERPGDSWRKRYKSLCLHDPVW
                     YDHLPYIPFPENWPVFAPKDKIGDWLEMYTKVMELNYWSSTTCKSARYDDVTKEWTVV
                     VERDGEEVVLRPKQLVLATGMSGKPNVPKLRGQDIFKGEQQHSSQHPGPDAYREKRVV
                     VIGSNNSAHDICAALWEGGADVTMVQRSSTHIVRSDTLMEIGLGDLYSERALAAGMTT
                     RKADLIFASLPYRIMHEFQIPLYEKMRERDAKFYADLEKAGFMLDWGADGSGLFMKYL
                     RRGSGYYIDVGACDLVIDGSIKLKSGSDVSHLTEDSVVLKDGTVLPADLVVYATGYGS
                     MNGWAADLISREVADKVGKVWGLGSDTPKDPGPWEGEQRNMWKPTQQEALWFHGGNLH
                     QSRHYSQYLSLQLKARCEGISTPVYGLQERHHLA"
     misc_feature    complement(493774..494058)
                     /locus_tag="Smed_4033"
                     /note="SnoaL-like domain; Region: SnoaL_2; pfam12680"
                     /db_xref="CDD:221707"
     misc_feature    complement(492337..493641)
                     /locus_tag="Smed_4033"
                     /note="Predicted flavoprotein involved in K+ transport
                     [Inorganic ion transport and metabolism]; Region: TrkA;
                     COG2072"
                     /db_xref="CDD:224983"
     misc_feature    complement(493027..493545)
                     /locus_tag="Smed_4033"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox_3; pfam13738"
                     /db_xref="CDD:222355"
     gene            complement(494181..495254)
                     /locus_tag="Smed_4034"
                     /db_xref="GeneID:5318334"
     CDS             complement(494181..495254)
                     /locus_tag="Smed_4034"
                     /note="PFAM: Alcohol dehydrogenase zinc-binding domain
                     protein; Alcohol dehydrogenase GroES domain protein;
                     KEGG: atc:AGR_L_281 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="YP_001312775.1"
                     /db_xref="GI:150376179"
                     /db_xref="InterPro:IPR002328"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="GeneID:5318334"
                     /translation="MRALRFHAARDLRIEDIQAPGEPAAGQVLVRNRFVGICGTDLHE
                     YAYGPIFVPKEPHPFTGAHGPQVLGHEFGGVVEAVGEGVTSVRAGDRVSVQPLIMPRA
                     GDFFADRGLFHLSTDLALAGLSWAWGGMAEYALLNEYNVEKIPEEMSDEEAALVEPSA
                     VAVYACDRGGVTAGSSVLVTGAGPIGVLTLLAARAAGAAQLFVSDINDARLEFASSIL
                     PDITPINPGRSNPGDVVRAATEGKVGCDVAIECVGNEHALKGCVDAVRKQGVVVQTGL
                     HPHENPIDWFQVTFKDIDLRGSWAYPTHYWPRVIRLIASGHLPAKQVVTGRIGLDRAV
                     ADGFDALLDPGGRHLKILIDLTN"
     misc_feature    complement(494193..495254)
                     /locus_tag="Smed_4034"
                     /note="Threonine dehydrogenase and related Zn-dependent
                     dehydrogenases [Amino acid transport and metabolism /
                     General function prediction only]; Region: Tdh; COG1063"
                     /db_xref="CDD:223991"
     misc_feature    complement(494193..495254)
                     /locus_tag="Smed_4034"
                     /note="(2R,3R)-2,3-butanediol dehydrogenase; Region:
                     butanediol_DH_like; cd08233"
                     /db_xref="CDD:176195"
     misc_feature    complement(order(494355..494363,494421..494426,
                     494493..494495,494499..494504,494577..494579,
                     494625..494627,494637..494642,494697..494714,
                     494772..494774,494784..494786,495126..495128,
                     495135..495143))
                     /locus_tag="Smed_4034"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176195"
     misc_feature    complement(order(494784..494786,495045..495047,
                     495135..495137,495141..495143))
                     /locus_tag="Smed_4034"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176195"
     gene            complement(495427..497301)
                     /locus_tag="Smed_4035"
                     /db_xref="GeneID:5318335"
     CDS             complement(495427..497301)
                     /locus_tag="Smed_4035"
                     /note="PFAM: sigma-54 factor interaction domain-containing
                     protein; helix-turn-helix Fis-type; GAF domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20102 putative acetoin catabolism regulatory
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family GAF modulated sigma54 specific
                     transcriptional regulator"
                     /protein_id="YP_001312776.1"
                     /db_xref="GI:150376180"
                     /db_xref="InterPro:IPR002078"
                     /db_xref="InterPro:IPR002197"
                     /db_xref="InterPro:IPR003018"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318335"
                     /translation="MFSHSEHIREIERVGRGLPVSRDETVVKSWMRCLEHHRLDPAQS
                     CEAYIVPETRLKEHRQQSEDLIGIARSGLEHLFRQVAGQNYVLLLSDREGVTVEFLGD
                     PLFNNSLRKAGLYLGSEWSEWRAGTCAVGACLETGEALTIHQTDHFDNTHTPLSCTAA
                     PIYDNKGELSAVLDISLLSSPILKASQNLALHLVTATVRRIELANLMAQARNQWVLRF
                     SRSPEFLDVDPEAAISIDGLGRIAGMTHGGAKILARSTGLDWRDPRKLIGEPVSRFFD
                     IEVDDLSDLTRRRPTQERLVFARDGNALFAHAIEPHSTVRAPVVSREQIPPALRRLGG
                     DAPVIAALQARAAKLARTGLPILVQGETGTGKEHLARAIHEGSGLKGQFVAINCAAIP
                     EQLIESELFGYLPGAFTGASAKGRKGLIEQADGGTLFLDEIGDMPLALQSRLLRVLAE
                     GEVLPVGGTVPRKVRIRVVSASHRPLQTLVAQGAFREDLYYRLNAATLSIPALRDRPD
                     FDWILEQLLKRHGDGELILSEAALAALKAHDWPGNIRELDNVVAVAAALAENGVVEIG
                     DLPDHLLVNADTVGGSEAGAALSLMLATCDWNISETARRLGLDRSTVHRQIKRYSLKR
                     "
     misc_feature    complement(495430..497301)
                     /locus_tag="Smed_4035"
                     /note="Transcriptional activator of acetoin/glycerol
                     metabolism [Secondary metabolites biosynthesis, transport,
                     and catabolism / Transcription]; Region: AcoR; COG3284"
                     /db_xref="CDD:225822"
     misc_feature    complement(495820..496248)
                     /locus_tag="Smed_4035"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(496201..496224)
                     /locus_tag="Smed_4035"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(495883..495885,496009..496011,
                     496198..496221))
                     /locus_tag="Smed_4035"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(496006..496023)
                     /locus_tag="Smed_4035"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(495826..495828)
                     /locus_tag="Smed_4035"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(495442..>495528)
                     /locus_tag="Smed_4035"
                     /note="Bacterial regulatory protein, Fis family; Region:
                     HTH_8; pfam02954"
                     /db_xref="CDD:202485"
     gene            complement(497461..498672)
                     /locus_tag="Smed_4036"
                     /db_xref="GeneID:5318336"
     CDS             complement(497461..498672)
                     /locus_tag="Smed_4036"
                     /note="catalyzed the formation of 2-ketoglutarate from
                     2-hydroxyglutarate"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyglutarate oxidase"
                     /protein_id="YP_001312777.1"
                     /db_xref="GI:150376181"
                     /db_xref="InterPro:IPR001613"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="GeneID:5318336"
                     /translation="MYDYCIIGGGIVGLSTAMALQDRVPGSRILLLEKEPELARHQTG
                     HNSGVIHAGIYYAPGSLKATLCREGAEATKAFCTENGIPFETCGKLLVATNDAEIEGM
                     ESLEDRARRNGIEYSRLSMSQLRSDEPNIAGLGALLVHATGIVDYSAVCRAMAARIEA
                     RGGEIRRGAEVSAIVEEAGSVRVASASGRFDARKLIACAGLQSDRIALMAGLTIHHRI
                     VPFRGEYYVLPSSKAALTRRLIYPIPDPGLPFLGIHLTRTIEGGMTVGPNAVLGFARE
                     GYPKGSFALADVADMAAFPGFWKMAARNWRSAIREFANSASRYRYLQECRKYCPSLTI
                     ADLSRAQSGIRAQAVTADGSLVHDFLFEETERMLHVCNAPSPAATSAIPIGRMIVDRL
                     LEGAARATETA"
     misc_feature    complement(497476..498672)
                     /locus_tag="Smed_4036"
                     /note="Predicted dehydrogenase [General function
                     prediction only]; Region: COG0579"
                     /db_xref="CDD:223652"
     misc_feature    complement(497497..498672)
                     /locus_tag="Smed_4036"
                     /note="hydroxyglutarate oxidase; Provisional; Region:
                     PRK11728"
                     /db_xref="CDD:183292"
     gene            complement(498798..499769)
                     /locus_tag="Smed_4037"
                     /db_xref="GeneID:5318337"
     CDS             complement(498798..499769)
                     /locus_tag="Smed_4037"
                     /note="KEGG: sme:SMb20100 putative dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative dehydrogenase"
                     /protein_id="YP_001312778.1"
                     /db_xref="GI:150376182"
                     /db_xref="GeneID:5318337"
                     /translation="MARIGYHASHEQFTPLDLLGWARAAEEAGFDCTMSSDHLAPWSE
                     RQGQSGFAWAWLGAALQATEKSFGLVTVPCGWRYHPAITAQAAATLAQMFPRRLAWLA
                     LGSGEALNEQAVGGVWPEKAERRARLLEAVEVIRELWAGRTVNRQAPIAVSEARLYTL
                     AEHPPALIAAALTPETAETAGEWADGLITVNQSSTKLAAIAEAFRRGGGDGKPLCLQV
                     HVSYAQTDEEARQNAFDQWRSNVLSPGQSETLRTPGEIESATKSVRPEDLDKHVRISS
                     DPGRHAAWIEEDIAAGFDEIYLHNVGRNQLEFIDVFGRSVLPRVRAF"
     misc_feature    complement(<499140..499766)
                     /locus_tag="Smed_4037"
                     /note="N5,N10-methylenetetrahydromethanopterin reductase
                     (Mer) catalyzes the reduction of
                     N5,N10-methylenetetrahydromethanopterin with reduced
                     coenzyme F420 to N5-methyltetrahydromethanopterin and
                     oxidized coenzyme F420; Region:
                     Tetrahydromethanopterin_reductase; cd01097"
                     /db_xref="CDD:238530"
     misc_feature    complement(498810..499760)
                     /locus_tag="Smed_4037"
                     /note="probable non-F420 flavinoid oxidoreductase; Region:
                     flavin_revert; TIGR03885"
                     /db_xref="CDD:188400"
     gene            complement(499771..501405)
                     /locus_tag="Smed_4038"
                     /db_xref="GeneID:5318338"
     CDS             complement(499771..501405)
                     /locus_tag="Smed_4038"
                     /note="PFAM: alpha amylase catalytic region;
                     SMART: alpha amylase catalytic sub domain;
                     KEGG: sme:SMb20099 putative trehalose synthase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase catalytic protein"
                     /protein_id="YP_001312779.1"
                     /db_xref="GI:150376183"
                     /db_xref="InterPro:IPR006047"
                     /db_xref="InterPro:IPR006589"
                     /db_xref="GeneID:5318338"
                     /translation="MNEAPWFTSSVIYGIDVRRFADGNGDGIGDFIGLRERVVYLSHL
                     GIDCVWLSPFFRSPFADNGYDVSDYYSVDPALGTLDDFLNFLHAAGEHGIRVIIDLVA
                     NHTSSEHPWFQAARRDARCRFRDYYVWSASPPPVAPDNKTAFPGEESSVWTYDELAQA
                     YYFHKFRHFQPDLNIANPAVRDELLRVVDYWLTLGVDGFRVDAAPFVIGETGIEHADP
                     RDPHGFLREMRELVEGRRRDGLLLGEADLSPEKLRPYFGEGKLDLLFNFVLSASFAAS
                     LARQKADLIGQALSIMPEPPPHRGWVNFLRNLDELNLDRLPEDIQQETFAAFAPDEEM
                     RIYGRGIRRRLAPMLEGNQTRLELAFSLLLSSPGVPLVLYGDEIGMGEDPSRPGREPV
                     RVPMQWNAGANAGFSTAQRARLIQPIVTDGPFAFKRINVEAQREDPRSLLNRVRAMIL
                     MRRSHKLFQRGRPIVLHTRDPALFALAYSDGTELFVVLHNLTEAKRRAEVELPGAIDA
                     RLKDVFGEGEVELSGQHLTMGLGPFGYAWLHSGRKD"
     misc_feature    complement(499789..501390)
                     /locus_tag="Smed_4038"
                     /note="trehalose synthase; Region: treS_nterm; TIGR02456"
                     /db_xref="CDD:233874"
     misc_feature    complement(500050..501390)
                     /locus_tag="Smed_4038"
                     /note="Alpha amylase catalytic domain found in Trehalose
                     synthetase; Region: AmyAc_TreS; cd11334"
                     /db_xref="CDD:200473"
     misc_feature    complement(order(500479..500484,500674..500676,
                     500797..500802,500806..500808))
                     /locus_tag="Smed_4038"
                     /note="active site"
                     /db_xref="CDD:200473"
     misc_feature    complement(order(500479..500481,500674..500676,
                     500800..500802))
                     /locus_tag="Smed_4038"
                     /note="catalytic site [active]"
                     /db_xref="CDD:200473"
     gene            complement(501405..501797)
                     /locus_tag="Smed_4039"
                     /db_xref="GeneID:5318339"
     CDS             complement(501405..501797)
                     /locus_tag="Smed_4039"
                     /note="PFAM: protein of unknown function DUF1362;
                     KEGG: sme:SMb20098 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312780.1"
                     /db_xref="GI:150376184"
                     /db_xref="InterPro:IPR009794"
                     /db_xref="GeneID:5318339"
                     /translation="MEAIGKRRWTIAGGHIPLGSNGMEPEFTSRDEIAVLNCSDSPAR
                     LRIQIHYADRPVVGPYDVEIAARRVRRIRFNDLIFPEALPLDVDFGAVIEADVPVVVQ
                     FTRLDSGTGSRSTIATAAYAARNLQGSR"
     misc_feature    complement(501426..501797)
                     /locus_tag="Smed_4039"
                     /note="Anabaena sensory rhodopsin transducer; Region:
                     ASRT; cl01751"
                     /db_xref="CDD:242687"
     gene            complement(501806..503035)
                     /locus_tag="Smed_4040"
                     /db_xref="GeneID:5318340"
     CDS             complement(501806..503035)
                     /locus_tag="Smed_4040"
                     /note="PFAM: molybdopterin dehydrogenase FAD-binding; FAD
                     linked oxidase domain protein; D-arabinono-14-lactone
                     oxidase;
                     KEGG: sme:SMb20097 hypothetical oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD linked oxidase domain-containing protein"
                     /protein_id="YP_001312781.1"
                     /db_xref="GI:150376185"
                     /db_xref="InterPro:IPR002346"
                     /db_xref="InterPro:IPR006094"
                     /db_xref="InterPro:IPR007173"
                     /db_xref="GeneID:5318340"
                     /translation="MANTPWSATSKNLDQDCHNWSGGLRFRPARLEVPEHEEAVAALV
                     RAAGRQGRTIRPVGSAHSSSEIYVTDDVLVSLANICGLHEHDSRCHRAAVGAGSQLTE
                     LSKELQSAGMTLSNFGDVATQTVGGAIGTGTHGSGRNFPNLSMMLVGGRLVTARGEIT
                     TFGVEEDLDFVRALRVSFGTLGILTSATLQLEPLHDLRRQEWCLGFEPCMEALDRLSR
                     ENRNFDFYWYPRSDEVKIRCLNPPGEEKTYGAFARLAKDETGPPHEVIPQHSDLPYRF
                     EEMEYSMPAEAGPDCMRKLRTRIKEKWRRSVGWRVLYRYIKRDDTWLSEAYGRDSVSI
                     SLHQNATLPYWDFFLDLEPVMRDHGGRPHWAKKHSLRATELKALYPMWDRFLALRQEL
                     DPEGRFLTPYLRRLLGC"
     misc_feature    complement(501812..502981)
                     /locus_tag="Smed_4040"
                     /note="FAD-linked oxidoreductase; Region: bact_FAD_ox;
                     TIGR01679"
                     /db_xref="CDD:130740"
     misc_feature    complement(502547..502954)
                     /locus_tag="Smed_4040"
                     /note="FAD binding domain; Region: FAD_binding_4;
                     pfam01565"
                     /db_xref="CDD:216574"
     misc_feature    complement(501818..502477)
                     /locus_tag="Smed_4040"
                     /note="D-arabinono-1,4-lactone oxidase; Region: ALO;
                     pfam04030"
                     /db_xref="CDD:217852"
     gene            complement(503037..503414)
                     /locus_tag="Smed_4041"
                     /db_xref="GeneID:5318608"
     CDS             complement(503037..503414)
                     /locus_tag="Smed_4041"
                     /note="PFAM: protein of unknown function DUF1362;
                     KEGG: sme:SMb20096 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312782.1"
                     /db_xref="GI:150376186"
                     /db_xref="InterPro:IPR009794"
                     /db_xref="GeneID:5318608"
                     /translation="MTHAIGSRRWAIADGYIPSSSASDDPALVSHESACVLNTGDTPA
                     KVEITLFFSDREPAGPFRFTVAARRTVHLRFNDLDDPEPVPRDTPYASLIEADTPVVV
                     QQTRLDSRQPSHALLSTIAYCQD"
     misc_feature    complement(503046..503405)
                     /locus_tag="Smed_4041"
                     /note="Anabaena sensory rhodopsin transducer; Region:
                     ASRT; pfam07100"
                     /db_xref="CDD:148609"
     gene            complement(503521..505338)
                     /locus_tag="Smed_4042"
                     /db_xref="GeneID:5318609"
     CDS             complement(503521..505338)
                     /locus_tag="Smed_4042"
                     /note="PFAM: thiamine pyrophosphate protein domain protein
                     TPP-binding; thiamine pyrophosphate protein central
                     region; thiamine pyrophosphate protein TPP binding domain
                     protein;
                     KEGG: sme:SMb20095 putative pyruvate oxidase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate binding domain-containing
                     protein"
                     /protein_id="YP_001312783.1"
                     /db_xref="GI:150376187"
                     /db_xref="InterPro:IPR000399"
                     /db_xref="InterPro:IPR011766"
                     /db_xref="InterPro:IPR012000"
                     /db_xref="InterPro:IPR012001"
                     /db_xref="GeneID:5318609"
                     /translation="MPNASDILIETLIEWKVEVVFGLPGDGINGIMEALRRRQDRIRF
                     VSVRHEQSAAFMACAYAKFTGRLGVCLATSGPGGTNLLTGLYDAKLDQMPVLAITGMQ
                     YHDLIETFSQQDVDLTRVFENVAVYNAQVNDAAHMENLANLACRSALSKRGVAHLSIA
                     NDVQERMAGGGRSRRNREGHMPSRFFEGRLVPREDDILRAADLLNAGRKVAILAGRGA
                     LEAKGLLRETADLLGAPVAKALLGKAVLPDDDPFTTGGIGILGTVPSQEIMQQCDTLL
                     IVGSTFPYIEYYPKPHAATGIQIDHDPQRIGLRYPVEVGLVGAAGETLRMLNERLQRK
                     ADRTFLEQAQEKTRNWRRELRAMEGDRSSPLKPQAAVGAFGRRIAANGIVVTDSGQNT
                     ELAARHVDLGADHMFAVSGALASMASGLPYAIAAGIAMPARPIYAVVGDGGFAMQLGE
                     FATAVRYEIPLKLLVIRNDMLNQIAWEQMMFLGNPQFACELPPIDFAAAAEAMGGRGF
                     TIRSFDEIDGVLDQAFAAEGPVVIQALVDRYEPLMPPKMPEDYARNFRAALPQTPGHE
                     KIEENLRHSSAGRKVTEEEPQAPHEAAPDANTGDLPGIP"
     misc_feature    complement(503662..505338)
                     /locus_tag="Smed_4042"
                     /note="thiamine pyrophosphate protein; Provisional;
                     Region: PRK08273"
                     /db_xref="CDD:181344"
     misc_feature    complement(504838..505332)
                     /locus_tag="Smed_4042"
                     /note="Pyrimidine (PYR) binding domain of POX; Region:
                     TPP_PYR_POX; cd07039"
                     /db_xref="CDD:132922"
     misc_feature    complement(order(504844..504846,505066..505071,
                     505078..505083,505090..505092,505102..505104,
                     505111..505113,505150..505155,505159..505164,
                     505171..505173,505183..505185,505192..505203,
                     505240..505245,505252..505254,505261..505263,
                     505267..505269,505282..505284))
                     /locus_tag="Smed_4042"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132922"
     misc_feature    complement(order(504844..504846,504979..504981,
                     505081..505083,505090..505092,505099..505104,
                     505111..505113,505186..505188,505192..505203,
                     505240..505245,505252..505254,505261..505263,
                     505267..505269))
                     /locus_tag="Smed_4042"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132922"
     misc_feature    complement(order(504844..504846,504901..504903,
                     504910..504912,504955..504957,504979..504981,
                     504985..504987,504991..504993,505081..505083,
                     505090..505092,505099..505104,505111..505113,
                     505186..505188,505192..505203,505240..505245,
                     505252..505254,505261..505263,505267..505269))
                     /locus_tag="Smed_4042"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:132922"
     misc_feature    complement(order(505099..505101,505120..505122,
                     505189..505191,505267..505269))
                     /locus_tag="Smed_4042"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132922"
     misc_feature    complement(504358..504750)
                     /locus_tag="Smed_4042"
                     /note="Thiamine pyrophosphate enzyme, central domain;
                     Region: TPP_enzyme_M; pfam00205"
                     /db_xref="CDD:215786"
     misc_feature    complement(503713..504249)
                     /locus_tag="Smed_4042"
                     /note="Thiamine pyrophosphate (TPP) family, Pyruvate
                     oxidase (POX) subfamily, TPP-binding module; composed of
                     proteins similar to Lactobacillus plantarum POX, which
                     plays a key role in controlling acetate production under
                     aerobic conditions. POX decarboxylates...; Region:
                     TPP_POX; cd02014"
                     /db_xref="CDD:238972"
     misc_feature    complement(order(503920..503925,503929..503931,
                     503935..503937,504010..504018,504091..504093,
                     504097..504099,504169..504171))
                     /locus_tag="Smed_4042"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238972"
     gene            505436..507154
                     /locus_tag="Smed_4043"
                     /db_xref="GeneID:5318610"
     CDS             505436..507154
                     /locus_tag="Smed_4043"
                     /note="PFAM: phospholipase D/Transphosphatidylase;
                     KEGG: sme:SMb20094 putative phospholipase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D/transphosphatidylase"
                     /protein_id="YP_001312784.1"
                     /db_xref="GI:150376188"
                     /db_xref="InterPro:IPR001736"
                     /db_xref="GeneID:5318610"
                     /translation="MAVLHRESPGKLYSAAMLLLEQITVERDSFPIGMHGIGSLDWKN
                     ALTGNTAGRLRRASRPIIKEAENVWRSAPARHLSFLVDAAAYYACLDTMFEEAEEQLW
                     ITGWDFDPRIKLRPEDPHAESLGSTLERLAAQKPDLKIRILIWAMGPIYSGKSLRLFR
                     KQQWAAHPQIELRFASHRALRGSHHQKLVCIDDRIAFAGGIDLTARRWDTPEHAAENE
                     LRRDPDGKPYDPVHDIQAIVEGEASRAIGDLCRARWTASTGEEVEAPRAKASKGARTW
                     PWPNGTVPILENCPVAIARTEPGSGKKRARREALRLTLDALRSARRHIYIENQYFASG
                     RIGQLLCDRLQEPDGPEVVIITTRSSHGLLERIVMGGNRDRLIRRLTQADRYGRLRVA
                     YPAVPAPDGSEQEVMIHSKVVAIDDRFFRVGSSNFNNRSESLDTECDVAVEAANEGHR
                     AAIAKIRNGLIAEHLDVHADAFAEALRETSSLIAAIDRLNTRPRGIRSFDGIDNGGAT
                     DLVWGTEIIDPQRPIRPFYRTHKLLRRWVGQLFALLARLLSSSRRAASSATDSDIKPS
                     GSGRKK"
     misc_feature    505475..506875
                     /locus_tag="Smed_4043"
                     /note="Phosphatidylserine/phosphatidylglycerophosphate/car
                     diolipin synthases and related enzymes [Lipid metabolism];
                     Region: Cls; COG1502"
                     /db_xref="CDD:224419"
     misc_feature    505664..506089
                     /locus_tag="Smed_4043"
                     /note="Catalytic domain, repeat 1, of uncharacterized
                     bacterial proteins with similarity to vertebrate
                     phospholipases, PLD1 and PLD2; Region:
                     PLDc_vPLD1_2_like_bac_1; cd09140"
                     /db_xref="CDD:197238"
     misc_feature    order(505988..505990,505994..505996,506033..506035,
                     506039..506041,506072..506074)
                     /locus_tag="Smed_4043"
                     /note="putative active site [active]"
                     /db_xref="CDD:197238"
     misc_feature    505988..505990
                     /locus_tag="Smed_4043"
                     /note="catalytic site [active]"
                     /db_xref="CDD:197238"
     misc_feature    506351..506767
                     /locus_tag="Smed_4043"
                     /note="Catalytic domain, repeat 2, of uncharacterized
                     bacterial proteins with similarity to vertebrate
                     phospholipases, PLD1 and PLD2; Region:
                     PLDc_vPLD1_2_like_bac_2; cd09143"
                     /db_xref="CDD:197241"
     misc_feature    order(506660..506662,506666..506668,506705..506707,
                     506711..506713,506744..506746)
                     /locus_tag="Smed_4043"
                     /note="putative active site [active]"
                     /db_xref="CDD:197241"
     misc_feature    506660..506662
                     /locus_tag="Smed_4043"
                     /note="catalytic site [active]"
                     /db_xref="CDD:197241"
     gene            complement(507049..507990)
                     /locus_tag="Smed_4044"
                     /db_xref="GeneID:5318611"
     CDS             complement(507049..507990)
                     /locus_tag="Smed_4044"
                     /note="KEGG: sme:SMb20093 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312785.1"
                     /db_xref="GI:150376189"
                     /db_xref="GeneID:5318611"
                     /translation="MSRKILARLFIAAGIAVAGWLIYRTLSQHSFNEIVGSIMRIPGR
                     DLFAGIGFVFLSYFCLTLFDTLAIRYVGRKLPYPQIAIASFTSLSIGHNVGGAALSSG
                     AIRYRFYSRWGLSAEEIAKVILFCGVTVGLGLIALAGLCFVAVPADAARLTGLSTSGA
                     FLLGAACIATAASYVLLACLLRGSVRIFRWSFEMPSVKIATLQVIVGVANFLCVSASL
                     HQLLSAFEEVSFIDTAMAYVGAGVTAIVSHVPGGIGVLEATIAFLLGSSASLGALIAF
                     RAIYFFLPLPLGLISLSVAELAARRDDDKSLASKAKS"
     sig_peptide     complement(507934..507990)
                     /locus_tag="Smed_4044"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.969) with cleavage site probability 0.958 at
                     residue 19"
     misc_feature    complement(507073..507984)
                     /locus_tag="Smed_4044"
                     /note="Predicted integral membrane protein [Function
                     unknown]; Region: COG0392"
                     /db_xref="CDD:223469"
     gene            508050..508778
                     /locus_tag="Smed_4045"
                     /db_xref="GeneID:5318612"
     CDS             508050..508778
                     /locus_tag="Smed_4045"
                     /note="PFAM: Endonuclease/exonuclease/phosphatase;
                     KEGG: sme:SMb20092 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase"
                     /protein_id="YP_001312786.1"
                     /db_xref="GI:150376190"
                     /db_xref="InterPro:IPR005135"
                     /db_xref="GeneID:5318612"
                     /translation="MRQRIRFLTYNVHSCFGTDRKLDPARIAAVIAECRPDVIALQEV
                     DVGRARTGGIDQAHMIATHLSMDAQFHPALHLEDEKYGDAVLTALPMRLIRAAPLPSS
                     GEPRGALWVEIDAAGVKLQVIVTHLGLRGAERLRQATALLGPGWLGAMEQGKTRLILA
                     GDLNATGRSASYRLLARQLKDVQLLTGNKPRPTFPSRLPLLRIDHVLIGDCIEVVSCQ
                     VHSSALARSASDHLPLLTELDVLA"
     misc_feature    508059..508766
                     /locus_tag="Smed_4045"
                     /note="Metal-dependent hydrolase [General function
                     prediction only]; Region: ElsH; COG3568"
                     /db_xref="CDD:226098"
     misc_feature    order(508080..508082,508176..508178,508425..508427,
                     508533..508535,508539..508541,508659..508661,
                     508737..508742)
                     /locus_tag="Smed_4045"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:197306"
     misc_feature    order(508176..508178,508737..508739)
                     /locus_tag="Smed_4045"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:197306"
     misc_feature    order(508425..508427,508539..508541,508740..508742)
                     /locus_tag="Smed_4045"
                     /note="putative phosphate binding site [ion binding];
                     other site"
                     /db_xref="CDD:197306"
     gene            complement(508902..509408)
                     /locus_tag="Smed_4046"
                     /db_xref="GeneID:5318613"
     CDS             complement(508902..509408)
                     /locus_tag="Smed_4046"
                     /note="PFAM: protein of unknown function DUF892;
                     KEGG: sme:SMb20091 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312787.1"
                     /db_xref="GI:150376191"
                     /db_xref="InterPro:IPR010287"
                     /db_xref="GeneID:5318613"
                     /translation="MATANEHLVAWLRDAHAMEEQAITMLTSQSGRLENYPELKSRID
                     RHLQETRDQAAMLERCLERLDGGTSSIKDISGKIMAFGQGLSGLFVSDEVVKGSLASY
                     TFEHMEIASYKILIAAAEQAGDQETKRVCESILQQEIAMADWLGEHAGEITRRFLERD
                     QRDVTAKH"
     misc_feature    complement(508965..509381)
                     /locus_tag="Smed_4046"
                     /note="Ferritin-like superfamily of diiron-containing
                     four-helix-bundle proteins; Region: Ferritin_like;
                     cd00657"
                     /db_xref="CDD:153097"
     misc_feature    complement(order(508986..508988,508995..508997,
                     509094..509096,509250..509252,509259..509261,
                     509352..509354))
                     /locus_tag="Smed_4046"
                     /note="dinuclear metal binding motif [ion binding]; other
                     site"
                     /db_xref="CDD:153097"
     gene            509738..510073
                     /locus_tag="Smed_4047"
                     /db_xref="GeneID:5318614"
     CDS             509738..510073
                     /locus_tag="Smed_4047"
                     /note="KEGG: sme:SMb20089 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312788.1"
                     /db_xref="GI:150376192"
                     /db_xref="GeneID:5318614"
                     /translation="MTREIQEKLKIYRLSPLAEPDDPNWQNASYQGEVVVAARSSGDA
                     RIVASEAELDFLEIDAKPAEGVTTDMASAFRSEKLYTVVEEGPAPEGTERGVLDGVVG
                     VDNIVSTQL"
     gene            complement(510148..512130)
                     /locus_tag="Smed_4048"
                     /db_xref="GeneID:5318615"
     CDS             complement(510148..512130)
                     /locus_tag="Smed_4048"
                     /EC_number="2.1.1.77"
                     /note="TIGRFAM: protein-L-isoaspartate
                     O-methyltransferase;
                     PFAM: protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase; Erythromycin esterase;
                     KEGG: sme:SMb20088 hypothetical fusion protein"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="YP_001312789.1"
                     /db_xref="GI:150376193"
                     /db_xref="InterPro:IPR000682"
                     /db_xref="InterPro:IPR007815"
                     /db_xref="GeneID:5318615"
                     /translation="MIDFSRARERMIASHLSRRGIRNDHVVKAMRVVPREAFVDPGFE
                     EFAYEDSALSIGHGQTISQPYIVALMIERAEVQPGDTVLEIGTGSGYAAAVLSRIAAH
                     VYTMERHAGLARIAGQRFADLRYKNIDVRVGDGTTGWPEAGPFDAILVAAGSPEIPYA
                     LKQQLDLGGHLVIPVGPPDEQRLLKVTRVSATTFKEQDLGGVRFVPLIGEYGWHDERA
                     EPRARQSLRPAPTLSQMVASAAEPLPAFDDPAFGRLFDRFAGRRVVLLGEASHGTSEF
                     YRARAAITRRLIEEHGFTIVAVEADWPDAAAIDRYVRHRAPGMLQDAPFQRFPVWMWR
                     NREVMEFVEWMRELNGSREASDRAGFHGLDIYNIRGSIAAVLRYLDQTDPQAAAVARA
                     RYGCLTPWQNEPSTYGRAAMTAGFRKCEEAVVEQCRELLEKQLEAGRGSGDELLDAVQ
                     NARLVASAERYYRIMYYAGPDSWNMRDSHMFETLEHLLNARGDQSKAVVWAHNSHIGD
                     ARHTDMGTAREELNIGQLCRERYGDQAVLIGFGTHSGRVAAASDWDGDMEVKTIRASL
                     EGSYERVLHDSGVARFLIDFARHAPLSECLLKPMLERFIGVIYRPETERLSHYSHASL
                     PRQFDAFVWFDETNPVEPLGPEHTRAGVPDTFPFGL"
     misc_feature    complement(511489..512112)
                     /locus_tag="Smed_4048"
                     /note="Protein-L-isoaspartate carboxylmethyltransferase
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: Pcm; COG2518"
                     /db_xref="CDD:225316"
     misc_feature    complement(511606..511890)
                     /locus_tag="Smed_4048"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(511678..511680,511726..511734,
                     511807..511812,511858..511878))
                     /locus_tag="Smed_4048"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     misc_feature    complement(510220..511248)
                     /locus_tag="Smed_4048"
                     /note="Erythromycin esterase; Region: Erythro_esteras;
                     pfam05139"
                     /db_xref="CDD:218461"
     gene            complement(512283..512834)
                     /locus_tag="Smed_4049"
                     /db_xref="GeneID:5318616"
     CDS             complement(512283..512834)
                     /locus_tag="Smed_4049"
                     /note="KEGG: sme:SMb20087 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312790.1"
                     /db_xref="GI:150376194"
                     /db_xref="GeneID:5318616"
                     /translation="MRVVAGLFDDYDEARGAVSDLEAAGFPSEDMSIVANNAGERYTS
                     GGAVPGATGLLMGLDLMVTPGIGPVVGAGWLASAAAGALTGECAGGIIETLTHSGLEE
                     EDAHLYAEGVRRGSALVVVRADEKLVAQADGILRNRNAVDISFRRRAFTEDGWTRFDA
                     ASNPYSLDEVTRERERLSPPALL"
     gene            complement(513026..513280)
                     /locus_tag="Smed_4050"
                     /db_xref="GeneID:5318617"
     CDS             complement(513026..513280)
                     /locus_tag="Smed_4050"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312791.1"
                     /db_xref="GI:150376195"
                     /db_xref="GeneID:5318617"
                     /translation="MCPFRALGGLAVLCIRSHCASSKLKPKPAVAGATEKGRECSDRI
                     FNAESSAGFPLISATAVGGTNSGLEGLGAGSGARERGPEV"
     gene            513420..513593
                     /locus_tag="Smed_4051"
                     /db_xref="GeneID:5318874"
     CDS             513420..513593
                     /locus_tag="Smed_4051"
                     /note="PFAM: protein of unknown function DUF1328;
                     KEGG: sme:SMb20084 hypothetical protein transmembrane"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312792.1"
                     /db_xref="GI:150376196"
                     /db_xref="InterPro:IPR009760"
                     /db_xref="GeneID:5318874"
                     /translation="MLKWALIFFVISLIAGFLGFSGISAATAGIAKILFYIAVIIFLV
                     FLVLALAVGGAVT"
     misc_feature    513420..>513515
                     /locus_tag="Smed_4051"
                     /note="Small integral membrane protein [Function unknown];
                     Region: COG5487; cl17674"
                     /db_xref="CDD:248228"
     sig_peptide     513420..513506
                     /locus_tag="Smed_4051"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.536 at
                     residue 29"
     gene            513604..513885
                     /locus_tag="Smed_4052"
                     /db_xref="GeneID:5318875"
     CDS             513604..513885
                     /locus_tag="Smed_4052"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312793.1"
                     /db_xref="GI:150376197"
                     /db_xref="GeneID:5318875"
                     /translation="MNAESSRRVPHPRLALQSRQRPAKVVNGRADLVWPERLLCRCPG
                     RLSWFSSDLPSAILGNLASGNDGFGYGLILEAASASPLATTGRSRPRRS"
     gene            513894..514157
                     /locus_tag="Smed_4053"
                     /pseudo
                     /db_xref="GeneID:5318876"
     gene            complement(514409..514648)
                     /locus_tag="Smed_4054"
                     /db_xref="GeneID:5318877"
     CDS             complement(514409..514648)
                     /locus_tag="Smed_4054"
                     /note="KEGG: sme:SMb20083 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312794.1"
                     /db_xref="GI:150376198"
                     /db_xref="GeneID:5318877"
                     /translation="MPVISPTVHSQQISRELECQRALEDEFLVLTALAEEAGWSWQEI
                     ALAMMELTEQYVAAMRPGSAMEARSLLRMHSKSLH"
     gene            514949..515764
                     /locus_tag="Smed_4055"
                     /db_xref="GeneID:5318878"
     CDS             514949..515764
                     /locus_tag="Smed_4055"
                     /note="KEGG: sme:SMb20082 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312795.1"
                     /db_xref="GI:150376199"
                     /db_xref="GeneID:5318878"
                     /translation="MTSMTPHSPSEGPSEPLALPQLVDEEAEAFVAEAIAELGRSGIP
                     FLIAGTFAVSAHTGISRPTKDLDVFCKPGDYIRILNHFKALGYAVEIEDDRWLGKVFK
                     GKSFFDVIFSSPNGTMMVSDSWFANALPVEIGPSICQVVAPTELVWSKSFIQLRHRYD
                     GADVAHVILKAYDRIDWTRLLGYMEAHWEVLLIHILNFRWIYPSERDKVPLWLVDELL
                     SRLAAQRDLPLPQTKICRGRMYSRPDYEIDVKEWGFADVGGDSDLSAETEDKD"
     gene            515764..516474
                     /locus_tag="Smed_4056"
                     /db_xref="GeneID:5318879"
     CDS             515764..516474
                     /locus_tag="Smed_4056"
                     /note="PFAM: metallophosphoesterase;
                     KEGG: sme:SMb20081 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="YP_001312796.1"
                     /db_xref="GI:150376200"
                     /db_xref="InterPro:IPR004843"
                     /db_xref="GeneID:5318879"
                     /translation="MSKLKVAAVADLHVKEDRSVSYTDLFAEVSRAADVLVIAGDLTD
                     LGKPAEAELLAADMKSCTIPVVAVLGNHDHQCDAVEEVSSILVKAGVHLLDGQSIEIA
                     GVGFCGTKGFIGGFGRHMLGAFGEAAIKTMVGTSVDEAIRLENALRATRAERALVVLH
                     YSPIPETVDGEPKEIYPFLGSSRLAETIDRFKVSAVVHGHAHKGAYQGKTPGGAPVFN
                     VAAHVEKPTGRPYAILEL"
     misc_feature    515764..516471
                     /locus_tag="Smed_4056"
                     /note="Predicted phosphoesterases, related to the Icc
                     protein [General function prediction only]; Region:
                     COG2129"
                     /db_xref="CDD:225040"
     misc_feature    515773..>516375
                     /locus_tag="Smed_4056"
                     /note="metallophosphatase superfamily, metallophosphatase
                     domain; Region: MPP_superfamily; cl13995"
                     /db_xref="CDD:246597"
     misc_feature    order(515794..515796,515800..515802,515884..515886,
                     515974..515979,516244..516246,516361..516363)
                     /locus_tag="Smed_4056"
                     /note="active site"
                     /db_xref="CDD:163614"
     misc_feature    order(515794..515796,515800..515802,515884..515886,
                     515974..515976,516244..516246,516361..516363)
                     /locus_tag="Smed_4056"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163614"
     gene            complement(516518..517819)
                     /locus_tag="Smed_4057"
                     /db_xref="GeneID:5318880"
     CDS             complement(516518..517819)
                     /locus_tag="Smed_4057"
                     /note="PFAM: Alcohol dehydrogenase zinc-binding domain
                     protein; Alcohol dehydrogenase GroES domain protein;
                     KEGG: sme:SMb20080 putative alcohol dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="YP_001312797.1"
                     /db_xref="GI:150376201"
                     /db_xref="InterPro:IPR002328"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="GeneID:5318880"
                     /translation="MRASGFDHLRSWEHLPQLRVWRNVKDEQSAVLFFFFQRLTRSSD
                     VKALTWHGKGDIRCESVPDPEIKDERDVIIKVTACAICGSDVHIFHGLIPSMENGDVL
                     GHETMGEVVEVGSGASNLKVGDRVVVPFTISCGECFFCRKGFYSACERTNPDREKAAK
                     LWGNSPAGLFGYSHLLGGYSGGQAEYLRVPHADVGPIKVPDELTDEQALFLSDIFPTG
                     YMAAEFCDIEPGQTIAVWGCGPVGQMAIRSAFLLGAERVIAIDTIAERLRLAETAGAV
                     TLDYIAEDIYDRIMEITHGRGADACIDAVGTEADSRASLGSLVDRVKVATFMGTDRPH
                     VLRQAIHCCRNFGTVSVVGVYGGYLDKVPFGSAINRGLTFRMAQTPVQRYLPALLDRI
                     EKGEIDPSFVVTHRGGLADGPELYKTFAERKDGCIKVVLRP"
     misc_feature    complement(516521..517684)
                     /locus_tag="Smed_4057"
                     /note="Glutathione-dependent formaldehyde dehydrogenase
                     related proteins, child 1; Region: FDH_like_1; cd08283"
                     /db_xref="CDD:176243"
     misc_feature    complement(516521..517684)
                     /locus_tag="Smed_4057"
                     /note="Threonine dehydrogenase and related Zn-dependent
                     dehydrogenases [Amino acid transport and metabolism /
                     General function prediction only]; Region: Tdh; COG1063"
                     /db_xref="CDD:223991"
     misc_feature    complement(order(516563..516565,516683..516691,
                     516758..516766,516815..516817,516902..516910,
                     516980..516982,517022..517024,517034..517042,
                     517097..517105,517109..517114,517169..517171,
                     517181..517183,517430..517432,517559..517561,
                     517568..517576))
                     /locus_tag="Smed_4057"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:176243"
     misc_feature    complement(order(517181..517183,517508..517510,
                     517568..517570,517574..517576))
                     /locus_tag="Smed_4057"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176243"
     misc_feature    complement(order(517376..517378,517400..517402,
                     517409..517411,517415..517420))
                     /locus_tag="Smed_4057"
                     /note="structural Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176243"
     gene            complement(517850..521068)
                     /locus_tag="Smed_4058"
                     /db_xref="GeneID:5318881"
     CDS             complement(517850..521068)
                     /locus_tag="Smed_4058"
                     /note="PFAM: Hemolysin-type calcium-binding region;
                     KEGG: sme:SMb20079 putative hemolysin-adenlyate cyclase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Hemolysin-type calcium-binding protein"
                     /protein_id="YP_001312798.1"
                     /db_xref="GI:150376202"
                     /db_xref="InterPro:IPR001343"
                     /db_xref="InterPro:IPR003995"
                     /db_xref="GeneID:5318881"
                     /translation="MAVINGTSGNNILIGTGSDDSLNGLAGDDLLQGLGGADIINGGA
                     GVDTADYREKAAPIVVTLTGATAATVFINGVAEDTLANVENVYGGSGDDFITGDALNN
                     LFRGGGGNDVLDGGGGNDTADYTDKTASVVVTLAGATPVTVFVNGIAEDMISNFENVY
                     GGSGDDILTGDDRDNILRGEVGNDILNGGIGADSLFGGEGNDTVDGGNGVDTFDLREK
                     TSSVLVQLNGANGATVFVGGVAEDTIRNVENIVGGSAGDTLTGDAAANKLSGARGNDW
                     LMGGSGADILDGGEDSDTADYSDKQAAIVVALNGGNPVTVTVGGLAEDSIAKIENIVG
                     GSGDDTLSGDAAANTFRGGLGADALDGGSGSDTADFSDKAQSVVLALNGAIDAVATVG
                     GTAEDSVRNIENIIGGAGNDQLTGDAAANMFRGGLGADVLDGAAGSDTADFSDKTSSL
                     VVTLAGASPATVLVGGIAEDTLRNIENIIGGSGNDVFVGDGLQNVFDGGAGTDTADYS
                     ASAKAIAVTLNGAIDARVFIGNAAEDTLRNVESITGSALADVITGDALANSLLGGGGA
                     DLLKGGGGQDVVDGGSGSDTIDFGDKTAAVVLTLAGVANTTATVGGVAEDTVRNIENI
                     FGGAGADVLTGDGNSNTIRGGAGADGLDGGAGVDTADYRDKVTSVVVTLSGANAALVK
                     VGGLNEDTIRNFENVAGGSAGDTLVGDDLANVLLGNDGADTLKGGLGSDVLDGGNGID
                     TADYLEKADAISVTLNGTTNATVLVGGVAEDVIRGVENILAGSGADTLVGDGASNTFR
                     GALGADFIDGGAGSDTADYREKAAAVDVTLFGAGDSFVFVGGVAEDTIRNIENVFGGK
                     GNDTLTGDDSANTLNGNDGKDLLTGGGGADILDGGAASDTANYRDKSASVSVTLNGAA
                     STAVMVGGVAEDTVRNIENVWGGTGNDSLSGDGNANLLSGGGGSDMLSGGAGADIFQF
                     DFALGASNVDMVLDFTAGDRLFLSKSVFTSLSGGSLASNQFYAAAGATEAQGVNQRVV
                     YDTTTGALYYDADGNLSGHTAVQFAVLSTQPGLTAGDFVLVV"
     misc_feature    complement(<520484..>520600)
                     /locus_tag="Smed_4058"
                     /note="Peptidase M10 serralysin C terminal; Region:
                     Peptidase_M10_C; pfam08548"
                     /db_xref="CDD:117125"
     misc_feature    complement(<520172..>520330)
                     /locus_tag="Smed_4058"
                     /note="Peptidase M10 serralysin C terminal; Region:
                     Peptidase_M10_C; pfam08548"
                     /db_xref="CDD:117125"
     misc_feature    complement(<519560..519754)
                     /locus_tag="Smed_4058"
                     /note="Peptidase M10 serralysin C terminal; Region:
                     Peptidase_M10_C; pfam08548"
                     /db_xref="CDD:117125"
     misc_feature    complement(<518819..>518986)
                     /locus_tag="Smed_4058"
                     /note="Peptidase M10 serralysin C terminal; Region:
                     Peptidase_M10_C; pfam08548"
                     /db_xref="CDD:117125"
     gene            complement(521724..522362)
                     /locus_tag="Smed_4059"
                     /db_xref="GeneID:5318882"
     CDS             complement(521724..522362)
                     /locus_tag="Smed_4059"
                     /note="PFAM: regulatory protein LuxR; response regulator
                     receiver; Sigma-70 region 4 type 2;
                     KEGG: sme:SMb20078 putative nitratenitrite response
                     regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="two component LuxR family transcriptional
                     regulator"
                     /protein_id="YP_001312799.1"
                     /db_xref="GI:150376203"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR013249"
                     /db_xref="GeneID:5318882"
                     /translation="MMHTVLLVDDHPLLLRGLQDIIAAAPDFTIVGATASGVEAISLI
                     SRLQPDIAVLDVAMPGMGGLEILRALRGTHRFTRVIFLTATISGPQVAEALKMGLSGL
                     LLKEYAPEALLDCMRQVAMGGKWLPADLMEKASQVSEDVTLERFSLLTPREREIAALI
                     CGGLSNRMIASRLGTSEGTIGIHLHNIFRKLDISNRATLAALHVQYTNTLKA"
     misc_feature    complement(521745..522350)
                     /locus_tag="Smed_4059"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    complement(522003..522347)
                     /locus_tag="Smed_4059"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(522045..522050,522057..522059,
                     522114..522116,522174..522176,522198..522200,
                     522333..522338))
                     /locus_tag="Smed_4059"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(522198..522200)
                     /locus_tag="Smed_4059"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(522174..522182,522186..522191))
                     /locus_tag="Smed_4059"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(522042..522050)
                     /locus_tag="Smed_4059"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(521757..521918)
                     /locus_tag="Smed_4059"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(521775..521777,521808..521822,
                     521826..521831,521835..521840,521862..521870,
                     521907..521915))
                     /locus_tag="Smed_4059"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(521760..521762,521769..521777,
                     521868..521870,521874..521876,521880..521882))
                     /locus_tag="Smed_4059"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(522359..524017)
                     /locus_tag="Smed_4060"
                     /db_xref="GeneID:5318883"
     CDS             complement(522359..524017)
                     /locus_tag="Smed_4060"
                     /note="PFAM: ATP-binding region ATPase domain protein;
                     histidine kinase dimerisation and phosphoacceptor region;
                     KEGG: sme:SMb20077 putative sensor histidine kinase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane sensor signal transduction
                     histidine kinase"
                     /protein_id="YP_001312800.1"
                     /db_xref="GI:150376204"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR011712"
                     /db_xref="GeneID:5318883"
                     /translation="MAITRNDATLRAYRPAKEFAGAAREWLLRTDPERLICLGRVITA
                     VFAILAIYLDPTRPNSMLYESRLVLGLYLLLAVALVFFPLRFSFVSPVHLLIHGVDAA
                     VVGWLTFLTNELASPFFSILPFVILAMTMRWGLKGASLGALIALIVQLVVGLPDLLDG
                     DAELNIFIMRSIYFVLIAATLGYFGAYRERSRQRLAQLAQWPSGAIGEDRLSWLSIVL
                     QHASGVLGDAHLLVIWREQEFESGCAAFWTSGRLQLADLRDPEFWRRHDPDGCDERHS
                     RSGEALNGLFADLPQIHANAGRPNCKVVSAAFSSLRYRGRVFVISYANSTDDMKDLTQ
                     IIATRVGTELERVALIQAARAEGRMRLARDLHDSVLQNLTAARLKLKLIGEAFPDGAR
                     QKLMEVGSLILEQQQCVRKFVDENRPGEEGNLARLDQDLPEFLDLLRMQWSCSIDVSI
                     GSPGMMVPRWMLFEIMQLISEAVANAVRHGRATVVRIGFIGSAGLLELDISDNGTGIA
                     DGLTSKKPFSLSQRIAELGGSLAICRSSPGIGLTITLPLKPGLR"
     misc_feature    complement(522377..>522976)
                     /locus_tag="Smed_4060"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: COG4585"
                     /db_xref="CDD:226951"
     misc_feature    complement(522767..522946)
                     /locus_tag="Smed_4060"
                     /note="Histidine kinase; Region: HisKA_3; pfam07730"
                     /db_xref="CDD:219540"
     misc_feature    complement(522383..522625)
                     /locus_tag="Smed_4060"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(522389..522391,522395..522400,
                     522413..522415,522428..522430,522497..522502,
                     522506..522508,522512..522514,522518..522520,
                     522584..522586,522593..522595,522605..522607))
                     /locus_tag="Smed_4060"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(522593..522595)
                     /locus_tag="Smed_4060"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(522500..522502,522506..522508))
                     /locus_tag="Smed_4060"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            complement(524152..525165)
                     /locus_tag="Smed_4061"
                     /db_xref="GeneID:5317890"
     CDS             complement(524152..525165)
                     /locus_tag="Smed_4061"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR; KR
                     domain protein;
                     KEGG: sme:SMb20076 short chain dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="short chain dehydrogenase"
                     /protein_id="YP_001312801.1"
                     /db_xref="GI:150376205"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5317890"
                     /translation="MLNLEGAVVVITGASSGVGQATAEAFARRGSKLVLAARDAAALH
                     EVARTCRKLGAEVLVAPTDVTNAEAVKGLAKKAMSFGRIDVWFSNVGVGAVGRFDETP
                     IEAHEQVIRTNLIGHFNDAHAAIPIFRKQGHGTFINMISLGGFASAPFAAAYSASKFG
                     LRGFSEALRAELAEERDIHICDVYPTFLDTPGVVHGANYTGRRLSVPPPVYNARRAAR
                     AILRLAERPRNKLTVGLVADLTRFAHFVAPETTTRLMARMTARYLSRAPRAATSHGNL
                     FRPPAVAGGIDGGLRSRHRVPIAATAAVCVVGLAVAALVLGRQGAAARRGHSGVARLF
                     RRT"
     misc_feature    complement(524272..525165)
                     /locus_tag="Smed_4061"
                     /note="short chain dehydrogenase; Provisional; Region:
                     PRK06139"
                     /db_xref="CDD:235713"
     sig_peptide     complement(525094..525165)
                     /locus_tag="Smed_4061"
                     /product="short chain dehydrogenase"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.940) with cleavage site probability 0.786 at
                     residue 24"
     misc_feature    complement(524455..525147)
                     /locus_tag="Smed_4061"
                     /note="classical (c) SDR, subgroup 3; Region: SDR_c3;
                     cd05360"
                     /db_xref="CDD:187618"
     misc_feature    complement(order(524593..524598,524602..524613,
                     524692..524694,524704..524706,524743..524751,
                     524830..524832,524893..524901,524974..524982,
                     525049..525057,525112..525123,525127..525129))
                     /locus_tag="Smed_4061"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187618"
     misc_feature    complement(order(524692..524694,524704..524706,
                     524743..524745,524827..524829))
                     /locus_tag="Smed_4061"
                     /note="active site"
                     /db_xref="CDD:187618"
     gene            complement(525241..525432)
                     /locus_tag="Smed_4062"
                     /db_xref="GeneID:5317891"
     CDS             complement(525241..525432)
                     /locus_tag="Smed_4062"
                     /note="KEGG: sme:SMb20075 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312802.1"
                     /db_xref="GI:150376206"
                     /db_xref="GeneID:5317891"
                     /translation="MKTPKEGAPGTTEQSPRWEGPKETRPRGYLPAKDDPERDRDAVG
                     ENLKDPHRGKLSDAGKTKR"
     gene            complement(525478..525720)
                     /locus_tag="Smed_4063"
                     /db_xref="GeneID:5317892"
     CDS             complement(525478..525720)
                     /locus_tag="Smed_4063"
                     /note="KEGG: sme:SMb20074 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312803.1"
                     /db_xref="GI:150376207"
                     /db_xref="GeneID:5317892"
                     /translation="MEKTKRQMPDPLDVKPDERPVENDSDLHPETGKPPLEPDDITNA
                     KAAREAARLKRDEYIVKSDLEDADQRNPLPDMKDQE"
     gene            525933..526790
                     /locus_tag="Smed_4064"
                     /db_xref="GeneID:5317893"
     CDS             525933..526790
                     /locus_tag="Smed_4064"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR; KR
                     domain protein;
                     KEGG: sme:SMb20073 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001312804.1"
                     /db_xref="GI:150376208"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR002424"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5317893"
                     /translation="MERFPQPPFPRQKQEMPGTTDQMQPLPDHGENSYQGSGRLRDKR
                     AIITGGDSGIGRAVALAFAREGADVLISYLSEHEDAMATKALVEEAGRKAVLAAGDIQ
                     SSDHCRRIVETAVRELGGVDILVNNAAHQASFKNIEDISDEEWELTFRVNMHAMFYLT
                     KAAVPHMKKGSVIINTASINADVPNPILLAYATTKGAIHNFSAGLAQMLAERGIRVNV
                     VAPGPIWTPLIPSTMPEDSVANFGKQVPMKRPGQPVELASAYVMLADPMSSYVSGATI
                     AVTGGKPFL"
     misc_feature    525981..526781
                     /locus_tag="Smed_4064"
                     /note="classical (c) SDR, subgroup 1; Region: SDR_c1;
                     cd05355"
                     /db_xref="CDD:187613"
     misc_feature    525981..526775
                     /locus_tag="Smed_4064"
                     /note="short chain dehydrogenase; Provisional; Region:
                     PRK06701"
                     /db_xref="CDD:235853"
     misc_feature    order(525981..525983,526077..526079,526083..526094,
                     526149..526154,526158..526160,526227..526235,
                     526311..526322,526383..526385,526398..526400,
                     526458..526466,526503..526505,526515..526517,
                     526593..526604,526608..526619,526653..526655)
                     /locus_tag="Smed_4064"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187613"
     misc_feature    order(526083..526088,526158..526160)
                     /locus_tag="Smed_4064"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:187613"
     misc_feature    order(526386..526388,526464..526466,526503..526505,
                     526515..526517)
                     /locus_tag="Smed_4064"
                     /note="active site"
                     /db_xref="CDD:187613"
     gene            526996..527913
                     /locus_tag="Smed_4065"
                     /db_xref="GeneID:5317894"
     CDS             526996..527913
                     /locus_tag="Smed_4065"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     KEGG: sme:SMb20072 putative rhizopine binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001312805.1"
                     /db_xref="GI:150376209"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5317894"
                     /translation="MSAAVLALIAGTAHAENIGISIARSDSAFLTILRNGMQDQAGKL
                     DGVTVQVEDAQNDTSRQLDQVQNFVSSGVDAIIVVAVDGDGTPALTKIATDAGIPIVY
                     ANHPPADVDKLPETAAFVGSNEIDSGTLETKEVCRLLGGKGAAYVLMGPLNNHSSLIR
                     TKDIHDVIATDECKGMSVIEEQSANWDRLEAANIMTNWLSAGREFDAVIANNDEMAIG
                     AIQAMKAAGIDMSKVVVGGIDATPDGLAAMAAGDLDVTVFQNAIAQGAAAMDAAVALS
                     RDQETERQIWVPFELVTPENMKDYATANQ"
     misc_feature    526996..527910
                     /locus_tag="Smed_4065"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     RbsB; COG1879"
                     /db_xref="CDD:224791"
     sig_peptide     526996..527043
                     /locus_tag="Smed_4065"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.979) with cleavage site probability 0.979 at
                     residue 16"
     misc_feature    527047..527874
                     /locus_tag="Smed_4065"
                     /note="Periplasmic binding proteins specific to
                     rhizopines; Region: PBP1_rhizopine_binding_like; cd06301"
                     /db_xref="CDD:107296"
     misc_feature    order(527080..527082,527305..527307,527473..527475,
                     527710..527712,527770..527772)
                     /locus_tag="Smed_4065"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107296"
     gene            528304..529494
                     /locus_tag="Smed_4066"
                     /db_xref="GeneID:5317895"
     CDS             528304..529494
                     /locus_tag="Smed_4066"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: sme:SMb20071 putative efflux protein"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001312806.1"
                     /db_xref="GI:150376210"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5317895"
                     /translation="MPLAIFALTIAAYAIGTTEFVIVGLLPTVATDLAISLPLAGLIV
                     SVYALGVTFGAPVLTALSRRIERKPLLLGLMALFIGGNTVAALSPNYEMLLVARVLSA
                     FAHGVFFSVGATIAADLVPEDRRASAIAMMFMGLTVAIVTGVPIGTYIGQAFGWRATF
                     WGVAALGVVAFAGIATLLPGSLTKAAPASLLDQVRVLGSGRLLLVFAMTALGYGGTFV
                     AFTFLAPILQEVTGFSENSVSLILVLYGVAIAGGNIAGGRIANTNPVKALIGLFLLQA
                     LVLVIFSFTAASPALTLVTLTALGFLSFANVPGLQLYVVQLAKEHRPGAVDVASALNI
                     AAFNLGIALGAWLGGRVVGSPLGLASTPWVGAILVSGALLLTLWSGLLDRRGECGEPL
                     AAAN"
     misc_feature    528304..529419
                     /locus_tag="Smed_4066"
                     /note="Arabinose efflux permease [Carbohydrate transport
                     and metabolism]; Region: AraJ; COG2814"
                     /db_xref="CDD:225371"
     misc_feature    528316..529419
                     /locus_tag="Smed_4066"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    order(528358..528360,528367..528375,528379..528384,
                     528433..528435,528442..528447,528454..528456,
                     528466..528471,528475..528480,528616..528621,
                     528628..528633,528640..528645,528652..528654,
                     528688..528693,528700..528705,528721..528723,
                     528940..528942,528949..528954,528961..528966,
                     528973..528975,529015..529017,529027..529029,
                     529039..529041,529054..529056,529198..529200,
                     529207..529212,529219..529221,529231..529236,
                     529243..529245,529288..529293,529300..529305,
                     529312..529317,529324..529326)
                     /locus_tag="Smed_4066"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            529696..531204
                     /locus_tag="Smed_4067"
                     /db_xref="GeneID:5317896"
     CDS             529696..531204
                     /locus_tag="Smed_4067"
                     /note="PFAM: Sulfate transporter/antisigma-factor
                     antagonist STAS; Xanthine/uracil/vitamin C permease;
                     sulphate transporter;
                     KEGG: sme:SMb20070 putative sulfate permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter"
                     /protein_id="YP_001312807.1"
                     /db_xref="GI:150376211"
                     /db_xref="InterPro:IPR002645"
                     /db_xref="InterPro:IPR006043"
                     /db_xref="InterPro:IPR011547"
                     /db_xref="GeneID:5317896"
                     /translation="MRRKSMKLTFTSYKREWFSNIRGDVLSGIVVALALIPEAIGFSV
                     IAGVDPKVGLFASFAIACVSAFTGGRPGMISAATAATAVLMVTLVKEYGLEYLFAATL
                     LMGLIQIAAGFLKLGRVMRFVSRSVITGFVNALAIMIFMAQLPELIGVPHVTYAMIGA
                     GLAIIYLFPYVTKAVPSPLVAIAALTAIAVWTGMDIRTVGDLGELPSSLPIFALPQVP
                     LTFETLQIVFPYSVGLAAVGLLESLLTAQIVDDMTDTTSNKSQECIGQGASNIASGLI
                     GGMGGCAMIGQSVINVTSGGRGRLSTFVAGALLLFLILVLDDIVRIIPMAALVAVMIM
                     VSIGTFSWRSILDLRRNPLPSSVVMLATVVTTVGTHDLAKGVLVGVLLSGIFFAGKVA
                     RLFHVRSILDQSGRERTYYVDGQIFFASTEGFVGAFDFAEPLDKVVIDVSGAHLWDIT
                     AVGALDKVVLKYRRHGVAVEVIGLNEASAHMLDRFAVHDKSEEAGAALTPAH"
     misc_feature    529696..531177
                     /locus_tag="Smed_4067"
                     /note="Sulfate permease and related transporters (MFS
                     superfamily) [Inorganic ion transport and metabolism];
                     Region: SUL1; COG0659"
                     /db_xref="CDD:223732"
     sig_peptide     529696..529836
                     /locus_tag="Smed_4067"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.764) with cleavage site probability 0.642 at
                     residue 47"
     misc_feature    529720..529920
                     /locus_tag="Smed_4067"
                     /note="Sulfate transporter N-terminal domain with GLY
                     motif; Region: Sulfate_tra_GLY; pfam13792"
                     /db_xref="CDD:205965"
     misc_feature    530026..530745
                     /locus_tag="Smed_4067"
                     /note="Sulfate transporter family; Region: Sulfate_transp;
                     pfam00916"
                     /db_xref="CDD:216188"
     misc_feature    530923..531174
                     /locus_tag="Smed_4067"
                     /note="Sulphate Transporter and Anti-Sigma factor
                     antagonist domain of SulP-like sulfate transporters, plays
                     a role in the function and regulation of the transport
                     activity, proposed general NTP binding function; Region:
                     STAS_SulP_like_sulfate_transporter; cd07042"
                     /db_xref="CDD:132913"
     gene            531330..532559
                     /locus_tag="Smed_4068"
                     /db_xref="GeneID:5317897"
     CDS             531330..532559
                     /locus_tag="Smed_4068"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: mes:Meso_1534 major facilitator superfamily MFS_1"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001312808.1"
                     /db_xref="GI:150376212"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5317897"
                     /translation="MPFSTFLVRNCRWLAGGFLLCFFSSFGQTFFISLSAGDIRREYG
                     LSHGSFGTLYMAATLLSALTLPQLGRIVDHIRACHVLLLTLPLLAFATLSMAYASTWL
                     WLFATIYLLRLFGQGMMTHNAMTAMGRWFSAQRGRAVSIASLGNQAGEALFPLVFVAL
                     APLIGWRQTWLFSAAAILLVGLPAIYVLIRTERMPSASDGPERRFAARHWTRSEVLRD
                     PVFWFALSGVLAPGFIATTIFFHQVYLVELRHWSLEVFAGAFVVSSTLTVVFSLVTGY
                     LIDRYSAVDILPFYLVPLAAACFTLAFIDSQWSAFAFMALLGASLGSSTTLFGALWPE
                     IYGVRHLGSIRAVIVALMVFATAMGPGITGFLIDAGVPYSWQIAGMGIYCLFGIFVMN
                     AVRSEVQSRNTVLPAEE"
     sig_peptide     531330..531413
                     /locus_tag="Smed_4068"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.983) with cleavage site probability 0.599 at
                     residue 28"
     misc_feature    531414..532502
                     /locus_tag="Smed_4068"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    order(531414..531416,531423..531431,531435..531440,
                     531489..531491,531498..531503,531510..531512,
                     531522..531527,531531..531536,531672..531677,
                     531684..531689,531696..531701,531708..531710,
                     531744..531749,531756..531761,531777..531779,
                     532020..532022,532029..532034,532041..532046,
                     532053..532055,532095..532097,532107..532109,
                     532119..532121,532128..532130,532140..532142,
                     532281..532283,532290..532295,532302..532304,
                     532314..532319,532326..532328,532359..532364,
                     532371..532376,532383..532388,532395..532397)
                     /locus_tag="Smed_4068"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     misc_feature    531414..532241
                     /locus_tag="Smed_4068"
                     /note="Major Facilitator Superfamily; Region: MFS_1;
                     pfam07690"
                     /db_xref="CDD:219516"
     gene            complement(532571..532780)
                     /locus_tag="Smed_4069"
                     /db_xref="GeneID:5317898"
     CDS             complement(532571..532780)
                     /locus_tag="Smed_4069"
                     /note="PFAM: protein of unknown function DUF1458;
                     KEGG: sme:SMb20068 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312809.1"
                     /db_xref="GI:150376213"
                     /db_xref="InterPro:IPR009923"
                     /db_xref="GeneID:5317898"
                     /translation="MGEHVYKKIELIGSSPNSITEAIDGAISRASKTTRNLDWFEVDE
                     IRGQIVNGKVAHYQVVMKVGFRIDE"
     misc_feature    complement(532577..532780)
                     /locus_tag="Smed_4069"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3360"
                     /db_xref="CDD:225896"
     gene            533031..533609
                     /locus_tag="Smed_4070"
                     /db_xref="GeneID:5317899"
     CDS             533031..533609
                     /locus_tag="Smed_4070"
                     /note="PFAM: intradiol ring-cleavage dioxygenase;
                     KEGG: sme:SMb21380 putative dioxygenase, slightly similar
                     to catechol 1,2-dioxygenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="intradiol ring-cleavage dioxygenase"
                     /protein_id="YP_001312810.1"
                     /db_xref="GI:150376214"
                     /db_xref="InterPro:IPR000627"
                     /db_xref="GeneID:5317899"
                     /translation="MLPTRRSLLTAFLAVPALPVCNRAAAQQPTLPLTPACRDDDDLT
                     PALTAGPFYKPDAPLRHDLSGDAPDGERITIAGYVLDGNCRPIARSLVEIWHADETGA
                     YDTRGYRLRGHQVTDERGRWWFSTIIPALYPGRTRHYHFRVRRPGAPVLTTQLFFPNE
                     PQNDGDRLYSPSLLLDLRDTEDGKFGRFDFVV"
     sig_peptide     533031..533111
                     /locus_tag="Smed_4070"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.817 at
                     residue 27"
     misc_feature    533211..533603
                     /locus_tag="Smed_4070"
                     /note="Intradiol dioxygenases catalyze the critical
                     ring-cleavage step in the conversion of catecholate
                     derivatives to citric acid cycle intermediates. This
                     family contains catechol 1,2-dioxygenases and
                     protocatechuate 3,4-dioxygenases which are mononuclear...;
                     Region: intradiol_dioxygenase; cd00421"
                     /db_xref="CDD:238241"
     misc_feature    order(533313..533315,533337..533339,533424..533426,
                     533433..533435,533442..533444,533448..533450,
                     533529..533531)
                     /locus_tag="Smed_4070"
                     /note="active site"
                     /db_xref="CDD:238241"
     gene            complement(533647..533832)
                     /locus_tag="Smed_4071"
                     /db_xref="GeneID:5318937"
     CDS             complement(533647..533832)
                     /locus_tag="Smed_4071"
                     /note="KEGG: sme:SMb20066 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312811.1"
                     /db_xref="GI:150376215"
                     /db_xref="GeneID:5318937"
                     /translation="MDEKTDRAKNKGESGTAKKKQPGHVGGDEARKAQEWGGGSKASK
                     GGVSDGDKRNPNSSAKS"
     gene            534033..534797
                     /locus_tag="Smed_4072"
                     /db_xref="GeneID:5318938"
     CDS             534033..534797
                     /locus_tag="Smed_4072"
                     /note="KEGG: ret:RHE_CH02153 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312812.1"
                     /db_xref="GI:150376216"
                     /db_xref="GeneID:5318938"
                     /translation="MSDTDSEYGAPGVGPSAEGAARTSTITALFDNRSQAEATVERLR
                     EAELGAATVQLVLGSGEGSAPAAPDGIWTALENFFFPSEDREIYAEGLRRGGYLVTVS
                     GIDDAGYMTARDILDDEGTIDLDERVDLWRRDGWSGWQRSTSPGMDTRAPTEETFGAA
                     AGDHASPSITRDHARSSATVRAYRSEAGAKPVESSGDASSFTNRDEGQPFGEPSYGAP
                     ATERAGGDRLGKDRVGWDGDRPHGSNGLSPSGRNSE"
     gene            534802..535206
                     /locus_tag="Smed_4073"
                     /db_xref="GeneID:5318939"
     CDS             534802..535206
                     /locus_tag="Smed_4073"
                     /note="PFAM: glutathione-dependent formaldehyde-activating
                     GFA;
                     KEGG: rru:Rru_A2242 glutathione-dependent
                     formaldehyde-activating, GFA"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde-activating
                     protein"
                     /protein_id="YP_001312813.1"
                     /db_xref="GI:150376217"
                     /db_xref="InterPro:IPR006913"
                     /db_xref="GeneID:5318939"
                     /translation="MPGANLITGSCLCGKRRYAFKGPPSHVGYCHCSMCRRATGGPFT
                     VLVRTEGSSVHWNTPPALYRSSPIAVRGFCPDCGSPLFLQYDDDPRLRFTAGTLDWPE
                     GLAPTDHYGVESRLPWDDSGPSLPAEETKERF"
     misc_feature    534820..535200
                     /locus_tag="Smed_4073"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3791"
                     /db_xref="CDD:226314"
     gene            complement(535254..535652)
                     /locus_tag="Smed_4074"
                     /db_xref="GeneID:5318940"
     CDS             complement(535254..535652)
                     /locus_tag="Smed_4074"
                     /note="KEGG: sme:SMb20065 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312814.1"
                     /db_xref="GI:150376218"
                     /db_xref="GeneID:5318940"
                     /translation="MAQEKRLGSTIPRGVVDTKNGSVGVPNQASIEEEVRSLREQVNA
                     LSERLSELGISSGRAIANTGRRAGEMAREHPAWTALAVIGLLGLLAAGTSRPYWHSRS
                     SSRIEDLIADIEDRLSDLKSRYWSNSWRPW"
     gene            complement(536095..536784)
                     /locus_tag="Smed_4075"
                     /db_xref="GeneID:5318941"
     CDS             complement(536095..536784)
                     /locus_tag="Smed_4075"
                     /note="PFAM: isochorismatase hydrolase;
                     KEGG: sme:SMa0376 putative hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase hydrolase"
                     /protein_id="YP_001312815.1"
                     /db_xref="GI:150376219"
                     /db_xref="InterPro:IPR000868"
                     /db_xref="GeneID:5318941"
                     /translation="MSKLEVLTPENSQLIFIDQQPQMAFGVQSIDRQVLKNNVVGLAK
                     AAKIFNVPTTITTVETESFSGNTFPELLAVFPENDILERTSMNSWDDQNVRDALAKNA
                     ANGRKKIVVSGLWTEVCNTTFALSALHDVPDYEIYMVADASGGTSADAHKYAMDRMAQ
                     AGVIPVTWQQVLLEWQRDWARKETYDAVTTLVKEHSGAYGMGIDYAYTMVHKAAERVA
                     HGKRIGPNPAK"
     misc_feature    complement(536254..536745)
                     /locus_tag="Smed_4075"
                     /note="YcaC related amidohydrolases; E.coli YcaC is an
                     homooctameric hydrolase with unknown specificity. Despite
                     its weak sequence similarity, it is structurally related
                     to other amidohydrolases and shares conserved active site
                     residues with them; Region: YcaC_related; cd01012"
                     /db_xref="CDD:238494"
     misc_feature    complement(536275..536745)
                     /locus_tag="Smed_4075"
                     /note="Isochorismatase family; Region: Isochorismatase;
                     pfam00857"
                     /db_xref="CDD:216156"
     misc_feature    complement(order(536428..536430,536536..536538,
                     536731..536733))
                     /locus_tag="Smed_4075"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238494"
     misc_feature    complement(order(536575..536577,536713..536715,
                     536722..536724))
                     /locus_tag="Smed_4075"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238494"
     misc_feature    complement(536440..536445)
                     /locus_tag="Smed_4075"
                     /note="conserved cis-peptide bond; other site"
                     /db_xref="CDD:238494"
     gene            complement(536925..537857)
                     /locus_tag="Smed_4076"
                     /db_xref="GeneID:5318942"
     CDS             complement(536925..537857)
                     /locus_tag="Smed_4076"
                     /note="PFAM: Glyoxalase/bleomycin resistance
                     protein/dioxygenase;
                     KEGG: atc:AGR_L_1752 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance
                     protein/dioxygenase"
                     /protein_id="YP_001312816.1"
                     /db_xref="GI:150376220"
                     /db_xref="InterPro:IPR004360"
                     /db_xref="InterPro:IPR011588"
                     /db_xref="GeneID:5318942"
                     /translation="MIKDIKGLHHVTSMASDAQENNRFFTDVLGFRRVKKTVNFDDPS
                     VYHLYYGDEKGTPGTVMTYFPFSHMMTGRPGVGEVGETQFSVPKGSLAFWKDRLIAYG
                     VGGIQADATFGVERLRFAGPDGDRLALIETVDDARAPWLVDGISEEEAIRGFSGARFN
                     LHDTAATEELLRFMGYERTEVEGDVTRFTTPGGNGAATIDLVALPQTPFARQGAGSVH
                     HIAFAVENREKQLEVRKALMDTGYQVTPVIDRDYFWAIYFRTPGGILFEIATNEPGFD
                     RDEDTAHLGEALKLPTRYEPFREKIEAGLEPLAA"
     misc_feature    complement(537468..537839)
                     /locus_tag="Smed_4076"
                     /note="N-terminal domain of Sphingobium chlorophenolicum
                     2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and
                     similar proteins; Region: PcpA_N_like; cd08346"
                     /db_xref="CDD:211356"
     misc_feature    complement(order(537822..537824,537828..537830))
                     /locus_tag="Smed_4076"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:211356"
     misc_feature    complement(536934..537401)
                     /locus_tag="Smed_4076"
                     /note="C-terminal domain of Sphingobium chlorophenolicum
                     2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and
                     similar proteins; Region: PcpA_C_like; cd08347"
                     /db_xref="CDD:176695"
     misc_feature    complement(order(537057..537059,537201..537203))
                     /locus_tag="Smed_4076"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:176695"
     gene            537976..538875
                     /locus_tag="Smed_4077"
                     /db_xref="GeneID:5318943"
     CDS             537976..538875
                     /locus_tag="Smed_4077"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: atc:AGR_L_1754 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001312817.1"
                     /db_xref="GI:150376221"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318943"
                     /translation="MNDYKALKIFLLAAEKRNFAQVARELDMTPAGVTRAIAALEYDL
                     GIQLFVRTTRQVSLTTDGAIFAAQVQPAVAVLDNARRDVRNANKADQGRLRISAPTWL
                     GKTILPPILSGFRELYPKMSFEISLSDGLVDIVDGDYDLAIRISSAPSDKFTIWRKIS
                     VVRRVLVAAPGSRFHAMEHPGQLSPDDCLAYSGESRRETWVLSDGGSSMTISAGRAFS
                     ANSGEVLADMAADGAGVAMLPGFHVAEHLRTGRLVHILREWSPQDLWLTLYYPPYQAL
                     PPRIASFSKFFERQLPAHMAMLE"
     misc_feature    537982..538866
                     /locus_tag="Smed_4077"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    537988..538161
                     /locus_tag="Smed_4077"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    538249..538824
                     /locus_tag="Smed_4077"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator CrgA and its related
                     homologs, contains the type 2 periplasmic binding domain;
                     Region: PBP2_CrgA_like; cd08422"
                     /db_xref="CDD:176114"
     misc_feature    order(538279..538281,538291..538293,538408..538410,
                     538453..538455,538459..538461,538639..538641,
                     538690..538692,538771..538773)
                     /locus_tag="Smed_4077"
                     /note="putative effector binding pocket; other site"
                     /db_xref="CDD:176114"
     misc_feature    order(538282..538287,538297..538302,538306..538311,
                     538318..538320,538330..538332,538336..538356,
                     538534..538536,538621..538635,538654..538659,
                     538666..538668)
                     /locus_tag="Smed_4077"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176114"
     gene            complement(538967..539746)
                     /locus_tag="Smed_4078"
                     /db_xref="GeneID:5318944"
     CDS             complement(538967..539746)
                     /locus_tag="Smed_4078"
                     /note="PFAM: UbiE/COQ5 methyltransferase;
                     Methyltransferase type 11; Methyltransferase type 12;
                     KEGG: sme:SMb20059 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="type 11 methyltransferase"
                     /protein_id="YP_001312818.1"
                     /db_xref="GI:150376222"
                     /db_xref="InterPro:IPR004033"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="GeneID:5318944"
                     /translation="MDIRNHHLKDDIREYWSKRSETFDLAFGHRIPRGPEFDAWAAAV
                     RSALGARPLKVLELACGTGEVTGVLLSLGHDVTALDFSETMLAVARRKHAGNDKVRFI
                     LADAERTMEPDGTYDAVVCRHLVWTLTEPEQALAEWLRLLKPGGRLLVFDGDWSKPTP
                     LGRLASLAVAALERIIGYDPHYDGAMSERHAKIMERLPFGDGLTVERLVPLIEAAGFE
                     NILLPSRRPIAAAQRRNADLRNRLRTFFYRRFVLVCSRPSG"
     misc_feature    complement(538988..539719)
                     /locus_tag="Smed_4078"
                     /note="SAM-dependent methyltransferases [Secondary
                     metabolites biosynthesis, transport, and catabolism /
                     General function prediction only]; Region: SmtA; COG0500"
                     /db_xref="CDD:223574"
     misc_feature    complement(539297..539587)
                     /locus_tag="Smed_4078"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(539381..539383,539429..539437,
                     539504..539509,539555..539575))
                     /locus_tag="Smed_4078"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(539751..540557)
                     /locus_tag="Smed_4079"
                     /db_xref="GeneID:5318945"
     CDS             complement(539751..540557)
                     /locus_tag="Smed_4079"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20058 putative ABC transporter ATP-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312819.1"
                     /db_xref="GI:150376223"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318945"
                     /translation="MTLSAREISWSAGGTDILKEVSLTLETGEFLGIIGPNGSGKTSL
                     MSLIAGIRKPRKGEVFLDGSPIAALGRRAVAQRLALVEQQAETGERITARQAVELGRT
                     PYLGPLSPWSPQDDAIVDAALRNVDMGHLADRLWHTLSGGERQRLHIARALAQESKIL
                     LLDEPTNHLDIGHQISLLDLVRRQDRTVVAALHDLNHAAMFCDRIAVMQGGRLVALGR
                     PQEVLTVERIRAVFGIEVEVEQEFDGSCFIRYRARRRQPRPFSAIAAVGA"
     misc_feature    complement(539814..540557)
                     /locus_tag="Smed_4079"
                     /note="ABC-type cobalamin/Fe3+-siderophores transport
                     systems, ATPase components [Inorganic ion transport and
                     metabolism / Coenzyme metabolism]; Region: FepC; COG1120"
                     /db_xref="CDD:224045"
     misc_feature    complement(539907..540548)
                     /locus_tag="Smed_4079"
                     /note="ATP-binding component of iron-siderophores, vitamin
                     B12 and hemin transporters and related proteins; Region:
                     ABC_Iron-Siderophores_B12_Hemin; cd03214"
                     /db_xref="CDD:213181"
     misc_feature    complement(540432..540455)
                     /locus_tag="Smed_4079"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213181"
     misc_feature    complement(order(539979..539981,540066..540071,
                     540309..540311,540429..540437,540441..540446))
                     /locus_tag="Smed_4079"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213181"
     misc_feature    complement(540309..540320)
                     /locus_tag="Smed_4079"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213181"
     misc_feature    complement(540114..540143)
                     /locus_tag="Smed_4079"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213181"
     misc_feature    complement(540066..540083)
                     /locus_tag="Smed_4079"
                     /note="Walker B; other site"
                     /db_xref="CDD:213181"
     misc_feature    complement(540048..540059)
                     /locus_tag="Smed_4079"
                     /note="D-loop; other site"
                     /db_xref="CDD:213181"
     misc_feature    complement(539973..539993)
                     /locus_tag="Smed_4079"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213181"
     gene            complement(540554..541597)
                     /locus_tag="Smed_4080"
                     /db_xref="GeneID:5318946"
     CDS             complement(540554..541597)
                     /locus_tag="Smed_4080"
                     /note="PFAM: transport system permease protein; ABC-3
                     protein;
                     KEGG: sme:SMb20057 putative ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transport system permease"
                     /protein_id="YP_001312820.1"
                     /db_xref="GI:150376224"
                     /db_xref="InterPro:IPR000522"
                     /db_xref="InterPro:IPR001626"
                     /db_xref="GeneID:5318946"
                     /translation="MSRVLTLAGRTGTGRVGAVLAALLILIAALWLGAAIGETAIPFK
                     TVAQTVANRVWNAGYPLQPIDEGIIWSYRLSRAVVAASCGAALALSGAVLQSLLRNPL
                     ADPYILGISAGASTGAVSVAILGVGAGLLTLPLGAFIGALVAFVLVSLLAAKAGRGTA
                     AIILAGVAGSQLFNALTSFIVTKAATAEQARGIMFWLLGNLSGVRWPDAWLAVPATLL
                     GLVVCLWHARSLDAFTFGSESAASLGISVRRTYFALVGVSAMMTAVMVSIVGSIGFVG
                     LVIPHSARMLVGVRHGVLLPAAALIGAVFMILADILSRILIPGQVLPIGVITALVGAP
                     AFALILGQRRDRA"
     sig_peptide     complement(541484..541597)
                     /locus_tag="Smed_4080"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.958) with cleavage site probability 0.881 at
                     residue 38"
     misc_feature    complement(540566..>541303)
                     /locus_tag="Smed_4080"
                     /note="iron-hydroxamate transporter permease subunit;
                     Provisional; Region: PRK10577"
                     /db_xref="CDD:236720"
     misc_feature    complement(540578..541303)
                     /locus_tag="Smed_4080"
                     /note="Transmembrane subunit (TM), of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters involved in the uptake of siderophores, heme,
                     vitamin B12, or the divalent cations Mg2+ and Zn2+.
                     PBP-dependent ABC transporters consist of...; Region:
                     TM_ABC_iron-siderophores_like; cd06550"
                     /db_xref="CDD:119348"
     misc_feature    complement(order(540725..540727,540746..540748,
                     540869..540877,540881..540898,540902..540907,
                     540911..540919,540923..540928,541295..541303))
                     /locus_tag="Smed_4080"
                     /note="ABC-ATPase subunit  interface; other site"
                     /db_xref="CDD:119348"
     misc_feature    complement(order(540578..540580,540587..540592,
                     540599..540601,540608..540613,540620..540622,
                     540776..540778,541004..541006,541013..541018,
                     541055..541057,541061..541066,541073..541075,
                     541082..541087,541094..541099,541106..541111,
                     541115..541117,541277..541279,541292..541294,
                     541298..541300))
                     /locus_tag="Smed_4080"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    complement(order(540629..540631,540656..540658,
                     540788..540790,540800..540802,540974..540976,
                     541055..541057))
                     /locus_tag="Smed_4080"
                     /note="putative PBP binding regions; other site"
                     /db_xref="CDD:119348"
     gene            complement(541594..542697)
                     /locus_tag="Smed_4081"
                     /db_xref="GeneID:5317900"
     CDS             complement(541594..542697)
                     /locus_tag="Smed_4081"
                     /note="PFAM: periplasmic binding protein;
                     KEGG: sme:SMb20056 putative ABC transporter periplasmic
                     solute-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein"
                     /protein_id="YP_001312821.1"
                     /db_xref="GI:150376225"
                     /db_xref="InterPro:IPR002491"
                     /db_xref="GeneID:5317900"
                     /translation="MNSFLKGPLAAGLILFSIGISGFGSPAAAAETAYPLTLENCGRQ
                     VTFERRPTRTVSIGQSSTEILYLLGLADKVVGTALWVGQVLKGYEEINAKVERLADND
                     PSFESVLAKKPDMVAVQFQWQVGPEGVVARPEQFEELGIPVYTSPADCTGKENSAASD
                     GVRRQPFTMDLVYREIRELAQIYDVQDTGAAVVAGLKSREEAARAKVASVEGKLSAVF
                     WFSSAADADPYVAGSNGAPGYIMAALGIENIIKTEDEWPTVGWETIAKAEPSMIVAGS
                     MERRRYPLDSLEAKLEFLKGDPVASLMPAVAKGHVFGMDAQAMNPTIRTIDGIEALAE
                     AIVEAGLASKGGLGSKSGLGSDGGLADRAGLAK"
     sig_peptide     complement(542608..542697)
                     /locus_tag="Smed_4081"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.809 at
                     residue 30"
     misc_feature    complement(541699..542598)
                     /locus_tag="Smed_4081"
                     /note="Metal binding protein TroA_a.  These proteins are
                     predicted to function as initial receptors in ABC
                     transport of metal ions in eubacteria. They belong to the
                     TroA superfamily of helical backbone metal receptor
                     proteins that share a distinct fold and...; Region:
                     TroA_a; cd01148"
                     /db_xref="CDD:238568"
     misc_feature    complement(541684..542595)
                     /locus_tag="Smed_4081"
                     /note="proposed F420-0 ABC transporter, periplasmic F420-0
                     binding protein; Region: F420-O_ABCperi; TIGR03868"
                     /db_xref="CDD:163580"
     misc_feature    complement(542434..542436)
                     /locus_tag="Smed_4081"
                     /note="putative ligand binding residues [chemical
                     binding]; other site"
                     /db_xref="CDD:238568"
     misc_binding    complement(542876..543105)
                     /note="Cobalamin riboswitch as predicted by Rfam
                     (RF00174), score 124.44"
                     /bound_moiety="adenosylcobalamin"
     gene            complement(543503..543886)
                     /locus_tag="Smed_4082"
                     /db_xref="GeneID:5317901"
     CDS             complement(543503..543886)
                     /locus_tag="Smed_4082"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312822.1"
                     /db_xref="GI:150376226"
                     /db_xref="GeneID:5317901"
                     /translation="MALSDYERNNTISEICIRTITHPLTNVICIIAVVSLAAFASVPT
                     GIPPYMLAPIGFMLAITIDPADLISRLRARPAKPGSTAARTQSGDRSRRASGNGWSLR
                     FSRQVQHVERKAQAERRVCKGTRGR"
     gene            complement(544377..545402)
                     /locus_tag="Smed_4083"
                     /db_xref="GeneID:5317902"
     CDS             complement(544377..545402)
                     /locus_tag="Smed_4083"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type; ThiJ/PfpI domain protein;
                     KEGG: sme:SMb20055 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="YP_001312823.1"
                     /db_xref="GI:150376227"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="InterPro:IPR002818"
                     /db_xref="GeneID:5317902"
                     /translation="MPKAALRSKAEIGLMLYPGCQMAMVHGMTDLINIARQFSAERGG
                     AVARISHWRLRDDGCLARSFDTHPELGSREMPEILLVPGRLTGPMEAEEAAPYARWLL
                     DGHAQGATLASTCGGTFVLAATGLLKGRPATTHWLFANAFRDRFPDVRLDTDKIVIED
                     GDIVTAGGLMAWTDLGMRLVDRLFGPTVTVETGRFLLIDPAGREQRHYSSFSPRLNHG
                     DEVILKVQHWLQAREARAVSVAQMAKVVAMEERTFLRRFKAATGMKPIEYAQHLRVGK
                     ARELLEFTRRSVEQVAWAVGYEDAAAFRKLFHRIVGLSRGDYRHRFAVAGEAFSRPVT
                     GLEQIDV"
     misc_feature    complement(544431..545402)
                     /locus_tag="Smed_4083"
                     /note="Transcriptional regulator containing an amidase
                     domain and an AraC-type DNA-binding HTH domain
                     [Transcription]; Region: COG4977"
                     /db_xref="CDD:227311"
     misc_feature    complement(544806..545369)
                     /locus_tag="Smed_4083"
                     /note="AraC transcriptional regulators having a Type 1
                     glutamine amidotransferase (GATase1)-like domain; Region:
                     GATase1_AraC_2; cd03138"
                     /db_xref="CDD:153232"
     misc_feature    complement(545058..545060)
                     /locus_tag="Smed_4083"
                     /note="conserved cys residue [active]"
                     /db_xref="CDD:153232"
     misc_feature    complement(544443..544553)
                     /locus_tag="Smed_4083"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     gene            545675..546379
                     /locus_tag="Smed_4084"
                     /db_xref="GeneID:5317903"
     CDS             545675..546379
                     /locus_tag="Smed_4084"
                     /EC_number="1.11.1.10"
                     /note="PFAM: alpha/beta hydrolase fold;
                     KEGG: sme:SMb20054 putative non-heme chloroperoxidase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride peroxidase"
                     /protein_id="YP_001312824.1"
                     /db_xref="GI:150376228"
                     /db_xref="InterPro:IPR000073"
                     /db_xref="InterPro:IPR003089"
                     /db_xref="InterPro:IPR008262"
                     /db_xref="GeneID:5317903"
                     /translation="MVFFASKGYRVVAHDRRSHGRSDQVWDNNTMDQYADDLAELIEA
                     LDLRDVILVGHSTGGGEVTRFIGRHGTGRVAKVALIGAVPPLMLKTEANPGGLPIDVF
                     DGIRKGTYDNRSQFFRDLVTPFYGYNREGAVISEGIRESFWLQGMMGGLKGHLDSIRA
                     FSESDFNADLAKFDKPTLVLPGDDDQIVPIGASAHSTVKIVRHAVLKVYEGADHGLTQ
                     TYQDRFNADLLKFIEI"
     misc_feature    545699..546364
                     /locus_tag="Smed_4084"
                     /note="alpha/beta hydrolase fold; Region: Abhydrolase_1;
                     pfam00561"
                     /db_xref="CDD:201306"
     gene            546564..546881
                     /locus_tag="Smed_4085"
                     /db_xref="GeneID:5317904"
     CDS             546564..546881
                     /locus_tag="Smed_4085"
                     /note="KEGG: sme:SMb20050 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312825.1"
                     /db_xref="GI:150376229"
                     /db_xref="GeneID:5317904"
                     /translation="MVGAISVLTLGVAFAALVALTPRGWARPAYAVSATFALYLKLFV
                     LVVQSFLKVPALQVLAPTQTEAPFVVARILLLVASIGLGKAAAVGSRQAALPLRAARG
                     AGA"
     sig_peptide     546564..546659
                     /locus_tag="Smed_4085"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.973) with cleavage site probability 0.671 at
                     residue 32"
     gene            complement(546951..548912)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /db_xref="GeneID:5317905"
     CDS             complement(546951..548912)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="EF-G; promotes GTP-dependent translocation of the
                     ribosome during translation; many organisms have multiple
                     copies of this gene"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="YP_001312826.1"
                     /db_xref="GI:150376230"
                     /db_xref="InterPro:IPR000640"
                     /db_xref="InterPro:IPR005517"
                     /db_xref="GeneID:5317905"
                     /translation="MRCFTVLGPSQIGKSTLVERVGSLEGEPKKSVTPYGLGLVEFEF
                     GGEVWCALDVSGNNEALAHAQHALLASDACVLCVSPVLEGAVLAAPYLRMIEASGTPC
                     ILFVNRMDEPRGRIRDIVAALQDFCSRPLILRQVPIREGDKIIGSCDLISERAWRYRE
                     GQPSSLFEIPESAAERENEARAELLEHLSEFDDWLLEELIEDRAPGSDAIYSISTRVL
                     NENKIIPVLLGSASHSNGLMRLMKALRHEAPRAEALRKRLAAGAGVGEANLLAVSFHA
                     HYRQSVGKTVLARALQNGVKQGAALGGSSLGALQDPASGRPIGSGVTEAGQLFAAVKS
                     DHLPVPSLLTAGAALAPPDWTTPPTPMLERILVPASERDETKLSETLAKLAETDRGLN
                     VMQEEGTGAQLVCAQGPVHLREVCRMLSDVFHVEVSDRPPSPVYRETVSKSSEVHYRH
                     RKQTGGAGQFADVKLSVHPNGRGDGFSFAETVKGGAVPRNFIPAVEAGAREAMEKGPL
                     GFKVIDVGVMLTDGQHHSVDSSEYAFRTAGKLGVRQALSQAASVLMQPVFRVDVHVPS
                     IYSGSLVPIVASLKGQVLGFDRDEEAKGWDIFRALLPGSALDDLARSLRSATQGIGYF
                     AKSFDHFEELYGKEAQAIVTAHGAPANEH"
     misc_feature    complement(548166..548906)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="Rat sarcoma (Ras)-like superfamily of small
                     guanosine triphosphatases (GTPases); Region:
                     Ras_like_GTPase; cl17170"
                     /db_xref="CDD:247724"
     misc_feature    complement(546984..548894)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="elongation factor G; Reviewed; Region: PRK12740"
                     /db_xref="CDD:237186"
     misc_feature    complement(548868..548891)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="G1 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(order(548217..548225,548583..548585,
                     548589..548594,548745..548747,548865..548885))
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206648"
     misc_feature    complement(548793..548801)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(548745..548756)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="G3 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(order(548694..548699,548745..548750))
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(548583..548594)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="G4 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(548217..548225)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="G5 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    complement(547266..547607)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="EFG_mtEFG1_IV: domains similar to domain IV of the
                     bacterial translational elongation factor (EF) EF-G.
                     Included in this group is a domain of mitochondrial
                     Elongation factor G1 (mtEFG1) proteins homologous to
                     domain IV of EF-G. Eukaryotic cells harbor 2...; Region:
                     EFG_mtEFG1_IV; cd01434"
                     /db_xref="CDD:238715"
     misc_feature    complement(547011..547250)
                     /locus_tag="Smed_4086"
                     /gene_synonym="fusA"
                     /note="EFG_mtEFG_C: domains similar to the C-terminal
                     domain of the bacterial translational elongation factor
                     (EF) EF-G.  Included in this group is the C-terminus of
                     mitochondrial Elongation factor G1 (mtEFG1) and G2
                     (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region:
                     EFG_mtEFG_C; cd03713"
                     /db_xref="CDD:239683"
     gene            complement(548997..549584)
                     /locus_tag="Smed_4087"
                     /db_xref="GeneID:5317906"
     CDS             complement(548997..549584)
                     /locus_tag="Smed_4087"
                     /note="PFAM: UbiC transcription regulator-associated
                     domain protein;
                     KEGG: sme:SMb20048 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiC transcription regulator-associated
                     domain-containing protein"
                     /protein_id="YP_001312827.1"
                     /db_xref="GI:150376231"
                     /db_xref="InterPro:IPR011663"
                     /db_xref="GeneID:5317906"
                     /translation="MTVNKALSELVKRGLIERRRKSGSYVSFPQAQSAVMEIHEVKRE
                     VQSLGLDYAYRLGERVVRKMTSGDKGRIDLPGSSRLLDITCSHFAGGRVFCLEERLIN
                     LSAVPEAETETFEAAAPGSWLLGKVPWSTAEHRIRAVAASRTTAQALEIAIGAACLVI
                     ERRTWSGGVPVTSVLLTYPGDRHELIAEFAPSATA"
     misc_feature    complement(549504..>549584)
                     /locus_tag="Smed_4087"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(549513..549524,549528..549533,
                     549561..549563,549570..549575,549579..549584))
                     /locus_tag="Smed_4087"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(549033..549446)
                     /locus_tag="Smed_4087"
                     /note="UTRA domain; Region: UTRA; pfam07702"
                     /db_xref="CDD:219527"
     gene            complement(549897..550085)
                     /locus_tag="Smed_4088"
                     /db_xref="GeneID:5317907"
     CDS             complement(549897..550085)
                     /locus_tag="Smed_4088"
                     /note="KEGG: sme:SMb20047 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312828.1"
                     /db_xref="GI:150376232"
                     /db_xref="GeneID:5317907"
                     /translation="MFYLGGMTLGYLVPPVRGSAARKTAAIDKPAEVSPCRETAPSDG
                     ERDQEWARAFLGPWHLFY"
     gene            550389..551585
                     /locus_tag="Smed_4089"
                     /db_xref="GeneID:5317908"
     CDS             550389..551585
                     /locus_tag="Smed_4089"
                     /note="PFAM: Cobyrinic acid ac-diamide synthase;
                     KEGG: sme:SMb20046 probable replication protein A"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinic acid ac-diamide synthase"
                     /protein_id="YP_001312829.1"
                     /db_xref="GI:150376233"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="GeneID:5317908"
                     /translation="MLQQRIQSLEEQEHLPSLLSADARELAHQLQEHQRKIFSPTSQK
                     TMRLFSPAEAAAFIGIGEGYLRQIASEGHGPQPLSNGRRMYTVEDIDRIRRVLDEGSK
                     TGKYIPHRRPGEKLQVISVMNFKGGSGKTTTSAHLAQYLALRGYRVLAIDLDPQASLS
                     ALFGHQPELDVGEGETLYGAIRYEAPRPVAEVVRSTYTANLHLIPGNLELMEFEHETP
                     KAMIAGSAETMFFARIGEVLSEIEGFYDIVVIDCPPQLGFLTMSALCAATSVLITVHP
                     QMLDVMSMSQFLSMTSELMAVVENAGGRTSYDWMRYLVTRFEPNDGPQSQMTGFMRAI
                     FGNRMLQNAMVKSTAISDAGVTKQTLYEVERAQFIRGTYDRAMDSLSLVNAEIEEMIR
                     KVWGRK"
     misc_feature    550434..551579
                     /locus_tag="Smed_4089"
                     /note="plasmid partitioning protein RepA; Region:
                     partition_RepA; TIGR03453"
                     /db_xref="CDD:234215"
     misc_feature    550740..>550856
                     /locus_tag="Smed_4089"
                     /note="ParA and ParB of Caulobacter crescentus belong to a
                     conserved family of bacterial proteins implicated in
                     chromosome segregation. ParB binds to DNA sequences
                     adjacent to the origin of replication and localizes to
                     opposite cell poles shortly following the...; Region:
                     ParA; cd02042"
                     /db_xref="CDD:238997"
     misc_feature    550761..550781
                     /locus_tag="Smed_4089"
                     /note="P-loop; other site"
                     /db_xref="CDD:238997"
     misc_feature    550779..550781
                     /locus_tag="Smed_4089"
                     /note="Magnesium ion binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238997"
     misc_feature    <551121..551258
                     /locus_tag="Smed_4089"
                     /note="ParA and ParB of Caulobacter crescentus belong to a
                     conserved family of bacterial proteins implicated in
                     chromosome segregation. ParB binds to DNA sequences
                     adjacent to the origin of replication and localizes to
                     opposite cell poles shortly following the...; Region:
                     ParA; cd02042"
                     /db_xref="CDD:238997"
     misc_feature    551139..551141
                     /locus_tag="Smed_4089"
                     /note="Magnesium ion binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238997"
     gene            551589..552590
                     /locus_tag="Smed_4090"
                     /db_xref="GeneID:5318905"
     CDS             551589..552590
                     /locus_tag="Smed_4090"
                     /note="TIGRFAM: parB-like partition protein;
                     PFAM: ParB domain protein nuclease; RepB plasmid
                     partition;
                     KEGG: sme:SMb20045 probable replication protein B"
                     /codon_start=1
                     /transl_table=11
                     /product="parB-like partition protein"
                     /protein_id="YP_001312830.1"
                     /db_xref="GI:150376234"
                     /db_xref="InterPro:IPR003115"
                     /db_xref="InterPro:IPR004437"
                     /db_xref="InterPro:IPR011111"
                     /db_xref="GeneID:5318905"
                     /translation="MARKNLIGISDSSAAPGDGERPAVGRPIAGLASQRSNGLVGGIT
                     RSLSNITQKVERAEELERQLVEGHAIVELEPALIDSSFIIDRLGVAPEVQAMLVQQIR
                     DHGQQVPILVRPHPTESGRYQVAYGHRRLAALREIGSRVKAVIRELSDEQLVISQGQE
                     NNARTDLSFIERALFAARLEDRGFSRDTIMSALGVDKAALSKMIAVVRRLPLDVIEAI
                     GAAPGFGRRRWMDLADLIDTAERRSKALDFIGAAEFQALESDQRFDKLFALLSRARKP
                     SKAEAWIAPDRSRPVRIRDTDAEMMLAFSKKAAPGFADFVRQRLEALYLEYQRETGD"
     misc_feature    551592..552575
                     /locus_tag="Smed_4090"
                     /note="plasmid partitioning protein RepB; Region:
                     partition_RepB; TIGR03454"
                     /db_xref="CDD:234216"
     misc_feature    551799..552074
                     /locus_tag="Smed_4090"
                     /note="ParB-like nuclease domain; Region: ParB;
                     smart00470"
                     /db_xref="CDD:214678"
     gene            552746..554059
                     /locus_tag="Smed_4091"
                     /db_xref="GeneID:5318906"
     CDS             552746..554059
                     /locus_tag="Smed_4091"
                     /note="PFAM: replication protein C;
                     KEGG: sme:SMb20044 probable replication protein C"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepC"
                     /protein_id="YP_001312831.1"
                     /db_xref="GI:150376235"
                     /db_xref="InterPro:IPR005090"
                     /db_xref="GeneID:5318906"
                     /translation="MERGSVTTPFGRRAMTLGMLASQIAAGDVPPDRSVDKWKLFRSL
                     CEAKTVIGVSDRSLAVLNALLSFYPGSELTGESGLVVFPSNAQLSLRTHGMAGTTLRR
                     HLACLVEAGLILRRDSPNGKRYARRGRSGSVGEAFGFDLSPLVVRANEFSTAAAELAA
                     ARQSLRLMRERLSLCRRDAAKLLELLRESATSVDWEQQQLRYEELATPLSRKASANDV
                     EAVYNAMSKLRSDLANQLEKLLNSAKLDANDRHNGRHIQNSEPDSKSESEPSLGKGRD
                     TFSTNPLTYRIHGTACRPNPSGISALTADEPPARPLLPPPTISRHAPQVPLPVLLSAC
                     LQIADYGPQGRIATWKDLTSAAVVVRTMLGVSTDAYDDACSVLGPENAATVVSCMLER
                     ADRISSPGGYLRDLTARARRQAFSLGPMVAALSRARMTAGTALAS"
     misc_feature    552746..554041
                     /locus_tag="Smed_4091"
                     /note="replication initiation protein RepC; Provisional;
                     Region: PRK13824"
                     /db_xref="CDD:184349"
     misc_feature    552782..553309
                     /locus_tag="Smed_4091"
                     /note="Replication protein C N-terminal domain; Region:
                     RP-C; pfam03428"
                     /db_xref="CDD:217551"
     misc_feature    553325..554038
                     /locus_tag="Smed_4091"
                     /note="Replication protein C C-terminal region; Region:
                     RP-C_C; pfam11800"
                     /db_xref="CDD:221230"
     gene            complement(554505..555347)
                     /locus_tag="Smed_4092"
                     /db_xref="GeneID:5318907"
     CDS             complement(554505..555347)
                     /locus_tag="Smed_4092"
                     /note="KEGG: sme:SMb20043 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312832.1"
                     /db_xref="GI:150376236"
                     /db_xref="GeneID:5318907"
                     /translation="MASEVLAASGGVKQLICINWGTKYGAPFINRLYAMVARNITPPF
                     TFTCFTDNREGLRPEILCEDLPPLDVERMPVNSKGIWPKARLWGPKLGNLKGPVLFLD
                     LDLVVVGSLDAFFEIGGPDDVMMTRNQTTPLERLGQTSLFRFPVGKLMPLQEKFRADP
                     QKVADEYEFEQRFVTRNAPGGAKFFPRRFVLHFRQDCRRPFPLNYFLPPRLPADARVV
                     IFPRGLLPQHAIDGQFGYKGRAVSPLTHVRGLFSSDRREKNAFRYLRHYILPSPWVAE
                     HWRE"
     gene            555788..556936
                     /locus_tag="Smed_4093"
                     /db_xref="GeneID:5318908"
     CDS             555788..556936
                     /locus_tag="Smed_4093"
                     /note="PFAM: protein of unknown function DUF1612;
                     KEGG: sme:SMb20042 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312833.1"
                     /db_xref="GI:150376237"
                     /db_xref="InterPro:IPR011670"
                     /db_xref="GeneID:5318908"
                     /translation="MRYEFPDPLDPALLPALMTAEDALARLDERTGRHAVAAGFRERG
                     QFFDATAALWVAGELVHVEDLVLHDSHMDARAPSHELTIAHAVLRARRRLELADADWA
                     FSTSGLSALRGEGGAVPNYEPRERSDPEGEANPTDAPDDPMDGSLSDAFAEIDAAIAR
                     SERLLEIHAGSVTEADSAAVELQTSRMEPTGQLGLLFDEEWDEAARLDAWRAVLPVAD
                     QLPATLGAAVLFDAWERIEPLRRQHWLGSLLVGAYLRLRGKVDSHVLAYNTGLKTIRH
                     ERRRSKDRLTRLAGFLEAMSAAAELGMKELDRLSLAKTQMEMRIRDRRSNSNLPGLID
                     LVLSRPIVSGPLIARHLGITPRGALNLVRELGVREMTGRGRYRGWGVL"
     misc_feature    556367..556753
                     /locus_tag="Smed_4093"
                     /note="Protein of unknown function (DUF1612); Region:
                     DUF1612; pfam07756"
                     /db_xref="CDD:149040"
     misc_feature    556772..556933
                     /locus_tag="Smed_4093"
                     /note="HTH DNA binding domain; Region: HTH_13; pfam11972"
                     /db_xref="CDD:152407"
     gene            complement(556957..557487)
                     /locus_tag="Smed_4094"
                     /db_xref="GeneID:5318909"
     CDS             complement(556957..557487)
                     /locus_tag="Smed_4094"
                     /note="KEGG: sme:SMb20041 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312834.1"
                     /db_xref="GI:150376238"
                     /db_xref="GeneID:5318909"
                     /translation="MKRRQLFRLLLVWLVLSAEMLPVETNAAPADEAAFLGSLEGRWT
                     GGGTVLLRIDKEAINVSCNFDSQANGTALSMRGTCRGLLVVSRSISADLRSDGSRYTG
                     IYVGPRGGRSALSGRRRGNAINLTVTWAREVNGDRKATLIVQKLGENGMRLSTVDVDP
                     ASGKRVVTSELNLRRS"
     sig_peptide     complement(557404..557487)
                     /locus_tag="Smed_4094"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.948) with cleavage site probability 0.649 at
                     residue 28"
     gene            complement(557654..558514)
                     /locus_tag="Smed_4095"
                     /db_xref="GeneID:5318910"
     CDS             complement(557654..558514)
                     /locus_tag="Smed_4095"
                     /note="PFAM: protein of unknown function DUF6
                     transmembrane;
                     KEGG: sme:SMb20040 hypothetical protein transmembrane"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312835.1"
                     /db_xref="GI:150376239"
                     /db_xref="InterPro:IPR000620"
                     /db_xref="GeneID:5318910"
                     /translation="MDKSASGWMSGFIGVVIFSGSLPATRVAVMDFDPIFLTVARATI
                     AGIIAVTLLFTFRERRPDRGDIVPLIVVSLGVVVGFPLLTALALRHVTSAHSIVFIGL
                     LPLATAIFGVIRGGERPRPAFWLFSCIGSAIVVGFASRQGFSASPVGDLLMLAAVIAC
                     GLGYAEGAKLSRKLGGWQVISWALALSLPLMTVLMLATMPASFADLSAASWIGFGYVS
                     VFSMLVGFIFWYRGLALGGTVAVGQLQLLQPFFGLALAATLLGEAVSWGMLAATLAIV
                     ACVAGARKFA"
     misc_feature    complement(<557837..>558250)
                     /locus_tag="Smed_4095"
                     /note="putative DMT superfamily transporter inner membrane
                     protein; Provisional; Region: PRK11272"
                     /db_xref="CDD:183067"
     gene            558595..560019
                     /locus_tag="Smed_4096"
                     /db_xref="GeneID:5318911"
     CDS             558595..560019
                     /locus_tag="Smed_4096"
                     /note="PFAM: regulatory protein GntR HTH; aminotransferase
                     class I and II;
                     KEGG: sme:SMb20039 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312836.1"
                     /db_xref="GI:150376240"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="GeneID:5318911"
                     /translation="MEREPVQMQRNAASSLGESLIAKVMGTVQQRIAARSLTPGSRLP
                     SIRSFALSMKVSKSTVVEAYERLQAEGLIRSRPGSGFYVAAPLAPLTLAEIGPPVDRA
                     VDPLWISRQALEPGEGVLRPGCGWLSPSWMPEEGLRRALRGIARGSSATLVDYGAPLG
                     LQPLRQLLARRVAQHGIEASPDQILLTESGTQAIDLLCRFLLKPGDAVLVDDPCYFNF
                     HALLRAHQARIVGVPYTPSGPDIGRFAEALTEHKPRLYITNSALHNPTGATLSPLVGH
                     RLLKLAEQSGLTIIEDDIFADFEEAPAPRLAAFDGLERVVHIGSFSKTLSAAVRCGFI
                     VAPRDWVEALTDLKIATCFGAAGFSSELVMALLKDGSYRKHLEAVRQRLAKAMADVAE
                     RLARIGITPWIEPQAGMFLWCRLPDGIDAAKLARESLGKGIVLAPGNVFSHAQTAAGF
                     LRFNVAQSQDDRLFRELEALMALA"
     misc_feature    558643..560016
                     /locus_tag="Smed_4096"
                     /note="Transcriptional regulators containing a DNA-binding
                     HTH domain and an aminotransferase domain (MocR family)
                     and their eukaryotic orthologs [Transcription / Amino acid
                     transport and metabolism]; Region: ARO8; COG1167"
                     /db_xref="CDD:224089"
     misc_feature    558679..558846
                     /locus_tag="Smed_4096"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    order(558724..558726,558730..558735,558757..558771,
                     558775..558780,558787..558789,558817..558822,
                     558826..558837)
                     /locus_tag="Smed_4096"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    559057..560001
                     /locus_tag="Smed_4096"
                     /note="Aspartate aminotransferase family. This family
                     belongs to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). Pyridoxal phosphate
                     combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine...; Region: AAT_like;
                     cd00609"
                     /db_xref="CDD:99734"
     misc_feature    order(559159..559167,559237..559239,559384..559386,
                     559477..559479,559552..559554,559558..559563,
                     559582..559584)
                     /locus_tag="Smed_4096"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99734"
     misc_feature    order(559168..559170,559267..559269,559456..559458,
                     559576..559584,559669..559671,559678..559680)
                     /locus_tag="Smed_4096"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99734"
     misc_feature    559561..559563
                     /locus_tag="Smed_4096"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
     gene            560251..561489
                     /locus_tag="Smed_4097"
                     /db_xref="GeneID:5318912"
     CDS             560251..561489
                     /locus_tag="Smed_4097"
                     /note="KEGG: sme:SMb20032 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312837.1"
                     /db_xref="GI:150376241"
                     /db_xref="GeneID:5318912"
                     /translation="MTLSLTRAHLMAAVAATLVFTAVGARADDHETEEAWRLFVADHK
                     QPVVRAIDFADGKELGRYDVKGYAALTVSASGQTVFAAQSDQDIVHLIKTGIDFSEHG
                     EHRDLKVSDAALLPVALEGKRPVHVVPHDDHAIIFYDRGGVAEIVDEAALLEGKKAQV
                     RTVDATKPHHGVAITMGQHVLVSVPNTEIEPEPDKLPPRIGLRVVDEKGNQVGEISEC
                     TDLHGEAMSARLVAFGCKEGVLVARPGGIDGPKLELLPYPSDFPKGHTGTLLGGKAMQ
                     FFLGNYGDDKVVLIDPDSSEPYRLITLPTRRVDFLLDPAIPANAYILTEDGDLHVLDV
                     VKGEIVRKGRVTEPYSKDGHWRDPRPRLAAADGQIAITDPRHSLVRVVDAETLKEIRT
                     ISVEGQPFAIVAVGGSGASH"
     sig_peptide     560251..560334
                     /locus_tag="Smed_4097"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.890 at
                     residue 28"
     gene            complement(561556..562413)
                     /locus_tag="Smed_4098"
                     /db_xref="GeneID:5318913"
     CDS             complement(561556..562413)
                     /locus_tag="Smed_4098"
                     /note="Member of the extracytoplasmic function sigma
                     factors which are active under specific conditions; binds
                     with the catalytic core of RNA polymerase to produce the
                     holoenzyme and directs bacterial core RNA polymerase to
                     specific promoter elements to initiate transcription"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor SigJ"
                     /protein_id="YP_001312838.1"
                     /db_xref="GI:150376242"
                     /db_xref="InterPro:IPR007627"
                     /db_xref="InterPro:IPR013249"
                     /db_xref="InterPro:IPR014284"
                     /db_xref="GeneID:5318913"
                     /translation="MTPATQAEAAASFDPLRPKLMRVAYRMLGSVADAEDMVQEAFIR
                     WMGADRATVREPEAFLRRTVTRLCLDQLKSARRQRETYVGPWLPDPVVEEEEEEDVTL
                     PLMLALERLSPLERAAFLLHDVFGLSFEEVAATVQRDTAACRQLAARARTHIREARPR
                     FHVEKERGLELAEAFFTASRSGDMNALGAMLAADVSIHADGGGKRPAATVPILGLDAV
                     MKVHEKLAALFQANGSKLLRVGFLNGLPGFITMEADGEIQTTALDIKGGKVAAIYVVR
                     NPDKLRHLH"
     misc_feature    complement(561559..562404)
                     /locus_tag="Smed_4098"
                     /note="RNA polymerase sigma factor SigJ; Provisional;
                     Region: PRK09636"
                     /db_xref="CDD:236600"
     misc_feature    complement(562180..562377)
                     /locus_tag="Smed_4098"
                     /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542"
                     /db_xref="CDD:218138"
     misc_feature    complement(561952..562104)
                     /locus_tag="Smed_4098"
                     /note="Sigma-70, region 4; Region: Sigma70_r4_2;
                     pfam08281"
                     /db_xref="CDD:203898"
     misc_feature    complement(order(561961..561963,561967..561972,
                     561976..561984,561988..561993,561997..561999,
                     562027..562032,562048..562050,562078..562080))
                     /locus_tag="Smed_4098"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:100119"
     gene            complement(562413..562886)
                     /locus_tag="Smed_4099"
                     /db_xref="GeneID:5318914"
     CDS             complement(562413..562886)
                     /locus_tag="Smed_4099"
                     /note="TIGRFAM: alkylhydroperoxidase like protein, AhpD
                     family;
                     PFAM: Carboxymuconolactone decarboxylase;
                     KEGG: sme:SMb20029 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alkylhydroperoxidase"
                     /protein_id="YP_001312839.1"
                     /db_xref="GI:150376243"
                     /db_xref="InterPro:IPR003779"
                     /db_xref="InterPro:IPR004675"
                     /db_xref="GeneID:5318914"
                     /translation="MTARLDPFAAAPSLMKNWFSISTAVASSLEPSLIELVKIRASQI
                     NGCANCINMHTAEARAKGETEQRIYLLSAWREAPCYTDRERAALAWTEALTRLSEGHE
                     HEHAYPALETEFTQEEQVKLTLMINVINGWNRLAVGFGLWVEPAAATAIAEKAVA"
     misc_feature    complement(562608..562853)
                     /locus_tag="Smed_4099"
                     /note="Carboxymuconolactone decarboxylase family; Region:
                     CMD; pfam02627"
                     /db_xref="CDD:202318"
     misc_feature    complement(562452..>562808)
                     /locus_tag="Smed_4099"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG2128"
                     /db_xref="CDD:225039"
     gene            complement(563000..563383)
                     /locus_tag="Smed_4100"
                     /db_xref="GeneID:5318989"
     CDS             complement(563000..563383)
                     /locus_tag="Smed_4100"
                     /note="PFAM: regulatory protein MerR; Transcription
                     regulator MerR DNA binding;
                     KEGG: rsp:RSP_7395 transcriptional regulator, MerR family"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="YP_001312840.1"
                     /db_xref="GI:150376244"
                     /db_xref="InterPro:IPR000551"
                     /db_xref="InterPro:IPR015358"
                     /db_xref="GeneID:5318989"
                     /translation="MKIGELSRRTGVSIRMLRYYEAEGLLAPHRTSAGYREYGRADER
                     TVDRIRLLGAAGMTLATIKQFLPCVRGEGPVFEPCDELRVTLNEQISLVDHKMERLAA
                     SRDVLSKFLHDIEKADRMIGSATQS"
     misc_feature    complement(563033..563383)
                     /locus_tag="Smed_4100"
                     /note="Predicted transcriptional regulators
                     [Transcription]; Region: SoxR; COG0789"
                     /db_xref="CDD:223860"
     misc_feature    complement(563048..563383)
                     /locus_tag="Smed_4100"
                     /note="Helix-Turn-Helix DNA binding domain of putative
                     transcription regulators from the MerR superfamily;
                     Region: HTH_MerR-like_sg3; cd01282"
                     /db_xref="CDD:133388"
     misc_feature    complement(order(563276..563284,563330..563332,
                     563372..563380))
                     /locus_tag="Smed_4100"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:133388"
     misc_feature    complement(order(563072..563077,563084..563086,
                     563096..563098,563114..563116,563126..563128,
                     563189..563191,563216..563221,563231..563233,
                     563240..563242))
                     /locus_tag="Smed_4100"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:133388"
     gene            563462..564277
                     /locus_tag="Smed_4101"
                     /db_xref="GeneID:5318990"
     CDS             563462..564277
                     /locus_tag="Smed_4101"
                     /note="KEGG: bur:Bcep18194_A5272 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312841.1"
                     /db_xref="GI:150376245"
                     /db_xref="InterPro:IPR001544"
                     /db_xref="GeneID:5318990"
                     /translation="MAASVNSFQIVLDGRKAAPEELNPLVFAGFAHFTAMQVRDGKVR
                     GMDLHLARLRAASVDFFGAALPDESLRSFMRIAIEDGSCEQSLTVTIFSRSGEFTSAG
                     IGSEPAALVRTGPPSKGPIGPLRLAVVNFERPLPTVKHVGEAAKTYYLHQAVRQGFDD
                     AAFVDRRGRLSEATIWNLVYWDGEAVVWPEAAVLAGVTMGVVSRQLKRLGIPQRREEI
                     TLENLKHLQGAAVMNSWTPGVPVTTIGQVVLPEAKPFIELLHKAYIAEPALSI"
     misc_feature    563477..564274
                     /locus_tag="Smed_4101"
                     /note="hypothetical protein; Provisional; Region:
                     PRK09266"
                     /db_xref="CDD:236438"
     misc_feature    563546..564250
                     /locus_tag="Smed_4101"
                     /note="Branched-chain amino acid
                     aminotransferase/4-amino-4-deoxychorismate lyase [Amino
                     acid transport and metabolism / Coenzyme metabolism];
                     Region: IlvE; COG0115"
                     /db_xref="CDD:223193"
     misc_feature    order(563558..563560,563615..563617,563876..563878,
                     563975..563977,564050..564055,564161..564163)
                     /locus_tag="Smed_4101"
                     /note="substrate-cofactor binding pocket; other site"
                     /db_xref="CDD:238254"
     misc_feature    order(563558..563560,563636..563638,563726..563728,
                     563732..563734,563792..563794,563882..563884,
                     563894..563896,563900..563902,563912..563914,
                     563954..563956)
                     /locus_tag="Smed_4101"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238254"
     misc_feature    order(563615..563617,563876..563878,563975..563977)
                     /locus_tag="Smed_4101"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238254"
     misc_feature    563876..563878
                     /locus_tag="Smed_4101"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238254"
     gene            complement(564366..565871)
                     /locus_tag="Smed_4102"
                     /db_xref="GeneID:5318991"
     CDS             complement(564366..565871)
                     /locus_tag="Smed_4102"
                     /note="PFAM: protein of unknown function DUF112
                     transmembrane;
                     KEGG: sme:SMb20027 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312842.1"
                     /db_xref="GI:150376246"
                     /db_xref="InterPro:IPR002823"
                     /db_xref="GeneID:5318991"
                     /translation="MELFSNLALGFATAGSPANLFFCLIGVLLGTLIGVLPGIGATAT
                     IAMLLPITFQLEPVSSLIMLAGIYYGAQYGGSTTAILINMPGESSSAVTAIDGYQMAR
                     KGRAGAALAIAALGSFFAGTVSTFLVALFAPPLTEIALEFGAAEYFSLMIVGLVSSIA
                     LAHGSVVKALAMVALGLLLGLVGTDIYTGTPRFTLGIREYSDGLNFVALAVGVFGIAE
                     ILRNLESEKTREVLMAKVTDLMPTREDFRQMVAPVLRGTAIGSALGVLPGGGAILAAF
                     ASYTVEKRLSDRPEEFGRGAVAGVAGPESANNAGAQTSFIPLLTLGIPANPVMALMIG
                     AMIIQGIVPGPNVATEQPALFWGIIASMWIGNLMLVVLNLPLIGLWVKLLTIPYFVLF
                     PIIMAFCSIGVYSVNSNVYDLYAVAFFGLVGYLLLKLRCEPAPLLLGFVLGPLLEENL
                     RRAMILSRGDASTFVTRPISATLLLLAAAVLVIVFLPSVKKKREQVFVEED"
     misc_feature    complement(564369..565871)
                     /locus_tag="Smed_4102"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3333"
                     /db_xref="CDD:225870"
     gene            complement(565982..566443)
                     /locus_tag="Smed_4103"
                     /db_xref="GeneID:5318992"
     CDS             complement(565982..566443)
                     /locus_tag="Smed_4103"
                     /note="PFAM: protein of unknown function DUF1468;
                     KEGG: sme:SMb20026 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312843.1"
                     /db_xref="GI:150376247"
                     /db_xref="InterPro:IPR009936"
                     /db_xref="GeneID:5318992"
                     /translation="MKSISFDATNALCGGILTAVGIFFAWQSFGLELGTALRMGPGYF
                     PLVLSAVLILLGLTILVQSARVKGEPMGPIAIRGIFFILPAPIFFGLTVRGLGFVPAI
                     FVTALIACFASSRMKPLWAIAVSLGLTIFSVAVFSYGLNLPFERFGPWTRF"
     sig_peptide     complement(566351..566443)
                     /locus_tag="Smed_4103"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.783) with cleavage site probability 0.737 at
                     residue 31"
     misc_feature    complement(566012..566416)
                     /locus_tag="Smed_4103"
                     /note="Tripartite tricarboxylate transporter TctB family;
                     Region: TctB; pfam07331"
                     /db_xref="CDD:219375"
     gene            complement(566649..567626)
                     /locus_tag="Smed_4104"
                     /db_xref="GeneID:5318993"
     CDS             complement(566649..567626)
                     /locus_tag="Smed_4104"
                     /note="PFAM: Uncharacterized protein UPF0065;
                     KEGG: sme:SMb20025 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312844.1"
                     /db_xref="GI:150376248"
                     /db_xref="InterPro:IPR005064"
                     /db_xref="GeneID:5318993"
                     /translation="MKILNALLSAAAAVSLFAVSASAQTYPERTITMVVPFSAGGPTD
                     TVARLVAESMSKDLGQQIIVENVGGAGGTLGAGRVAQAEPDGYTLLLHHIGMATSATL
                     YRKLAYDTLNAFEYVGLVTEVPMTIVARKDFEPTDLKSLIEHVKANKDTVTVANAGIG
                     AASHLCGMMFMSAIETPLTTVPYKGTGPAMTDLLGGQVDIMCDQTTNTTKQIQGGTIK
                     AYAVTSPERLKIFPDLPTAEEAGLSGFQVGIWHGVYAPKGTPAEVTDRLSKSLQKALK
                     DENVVARFGELGTEPSSDADATPAALKAKLESEIARWKPVIEAAGQYAD"
     sig_peptide     complement(567555..567626)
                     /locus_tag="Smed_4104"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.992 at
                     residue 24"
     misc_feature    complement(566655..567557)
                     /locus_tag="Smed_4104"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3181"
                     /db_xref="CDD:225722"
     gene            complement(567972..568754)
                     /locus_tag="Smed_4105"
                     /db_xref="GeneID:5318994"
     CDS             complement(567972..568754)
                     /locus_tag="Smed_4105"
                     /note="PFAM: RNA-binding S4 domain protein; pseudouridine
                     synthase;
                     KEGG: sme:SMb20024 pseudouridylate synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="YP_001312845.1"
                     /db_xref="GI:150376249"
                     /db_xref="InterPro:IPR000748"
                     /db_xref="InterPro:IPR002942"
                     /db_xref="InterPro:IPR006145"
                     /db_xref="GeneID:5318994"
                     /translation="MKQHRPAAGKRVDGGRERAGKRVTLARALSKLGYCTRTQAEKLI
                     AEGRVSVGGRRVTDLAHWVDIEADRIAVDGTVIAAQPKVYLMLNKPRGLVTTRDDPEG
                     RPTVFTCLETVDAPSLSPVGRLDKASEGLLLFTNDTVLAQRLLDPQTHLGKRYHVQVR
                     GFLGEAMAARMVEGVTEGGELLRAARVALLRGGDRNSWIEVELTEGRNRQIRRMLDAL
                     GFECLRLLRVAIGEVRLGDLPKGASRPLAEAEIRYLRRRTGL"
     misc_feature    complement(567975..568694)
                     /locus_tag="Smed_4105"
                     /note="16S rRNA uridine-516 pseudouridylate synthase and
                     related pseudouridylate synthases [Translation, ribosomal
                     structure and biogenesis]; Region: RsuA; COG1187"
                     /db_xref="CDD:224108"
     misc_feature    complement(568491..568682)
                     /locus_tag="Smed_4105"
                     /note="S4/Hsp/ tRNA synthetase RNA-binding domain; The
                     domain surface is populated by conserved, charged residues
                     that define a likely RNA-binding site;  Found in stress
                     proteins, ribosomal proteins and tRNA synthetases; This
                     may imply a hitherto unrecognized...; Region: S4; cd00165"
                     /db_xref="CDD:238095"
     misc_feature    complement(order(568563..568565,568569..568592,
                     568611..568613,568617..568622,568629..568634,
                     568638..568643,568647..568649))
                     /locus_tag="Smed_4105"
                     /note="RNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238095"
     misc_feature    complement(568065..568505)
                     /locus_tag="Smed_4105"
                     /note="Pseudouridine synthases, RsuA subfamily; Region:
                     PseudoU_synth_RsuA_like; cd02870"
                     /db_xref="CDD:211347"
     misc_feature    complement(order(568119..568121,568380..568391))
                     /locus_tag="Smed_4105"
                     /note="active site"
                     /db_xref="CDD:211347"
     gene            568942..572580
                     /locus_tag="Smed_4106"
                     /db_xref="GeneID:5318995"
     CDS             568942..572580
                     /locus_tag="Smed_4106"
                     /EC_number="3.5.2.9"
                     /note="PFAM: Hydantoinase/oxoprolinase; Hydantoinase
                     B/oxoprolinase; Hydantoinaseoxoprolinase domain protein;
                     KEGG: sme:SMb20023 N-methylhydantoinase / 5-oxoprolinase
                     (ATP-hydrolysing)"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase"
                     /protein_id="YP_001312846.1"
                     /db_xref="GI:150376250"
                     /db_xref="InterPro:IPR002821"
                     /db_xref="InterPro:IPR003692"
                     /db_xref="InterPro:IPR008040"
                     /db_xref="GeneID:5318995"
                     /translation="MSLTGTWDFWVDRGGTFTDVIGRDPSGALRALKVLSENPGAYRD
                     AAVHGIRLHLGLGSGEPVPHGLIGEVRMGTTVATNALLERKGERLGLVTTRGFRDALR
                     IGYQERKKIFATEIIKPEALYSGVVELDERVLADGTVELPLDEAAARRALESLKADGY
                     GAVAIVLLHAYKYPAHEMTVAHLARSIGFEQVSVSHEVSPLVKYVGRGDTTVIDAYLS
                     PVLGRYVAQVSQELDVGRSGARVMFMMSSGGLTAAEMFQGKDAILSGPAGGVVGLART
                     GEAAGFDRVIGFDMGGTSTDVAHFDGEYERAFETEVAGVRVRAPMMLIHTVAAGGGSI
                     LHFDGGRFRVGPDSAGANPGPACYRNGGPLAVTDANVMLGKLLPEHFPAIFGPEQNQP
                     LDVETVRERFAALAAEIGDGRSPEDVADGFIRIAVANMVEAIKKISVSRGYDVTRYAL
                     NCFGGAGGQHACLVADALGMKSILLHPMSGLLSAYGMGLADIRATRQKALGVALDEAA
                     PHAILELGHKLQSECLVELEAQGIALERIRTHLRAHIRYAGTDTVLPVEAAFPDQDDQ
                     ARLRRDFEHLHKRRFGFIAENKALMIDAVEVETVGGGAAEMEAEGLAATAGELVPDQR
                     IRFYSQGMFHDAPVALRSQVQPGQKLAGPAIIIEPNQTIVVEDGWQAELTTKDHIVLR
                     RVKALPERTAIGTKADPVMLEIFNNLFMSIAEQMGVTLQNTAYSVNIKERLDFSCAVF
                     DSGGSLVANAPHMPVHLGSMDASVATAIRENPVIHPGDVFLINAPYNGGTHLPDLTVC
                     TPVFDDAGREIRFWVASRGHHADIGGISPGSMSPLATDIEEEGVYIDNFRLIDRGRFC
                     EEGLEKLLTGARYPVRNLLQNVNDLKAQVAANEKGVAELKKMIAQFGEDVVEAYMGHV
                     QDNAAESVRRVIDQLPDGEFCYEMDQGCRIVVKISIDRGSREATVDFTGTSEQRADNF
                     NAPEPVTRAAVLYVFRVLVEADIPMNAGCLRPIRIVIPDGTMLSPRYPAAVVAGNVEV
                     SQAVTNCLFGAVGAQAAAQGTMNNLTFGNAEYQYYETICSGAPAGPGYDGADAVHTHM
                     TNSRLTDPEILETRFPVVLEDFHIRKDSGGCGKWSAGDGTERTIRARQRLDFAILSGH
                     RRVRPFGLKGGEPGEPGRNYVRRNDGRIEELPGSAHTVLEAGEAFTVVTPTGGGYGKD
                     EGPEEGQF"
     misc_feature    568966..572547
                     /locus_tag="Smed_4106"
                     /note="5-oxoprolinase; Region: PLN02666"
                     /db_xref="CDD:215358"
     misc_feature    568966..569505
                     /locus_tag="Smed_4106"
                     /note="Hydantoinase/oxoprolinase N-terminal region;
                     Region: Hydant_A_N; pfam05378"
                     /db_xref="CDD:218571"
     misc_feature    569560..570429
                     /locus_tag="Smed_4106"
                     /note="Hydantoinase/oxoprolinase; Region: Hydantoinase_A;
                     pfam01968"
                     /db_xref="CDD:216816"
     misc_feature    571027..572550
                     /locus_tag="Smed_4106"
                     /note="N-methylhydantoinase B/acetone carboxylase, alpha
                     subunit [Amino acid transport and metabolism / Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: HyuB; COG0146"
                     /db_xref="CDD:223224"
     gene            complement(572611..573177)
                     /locus_tag="Smed_4107"
                     /db_xref="GeneID:5318996"
     CDS             complement(572611..573177)
                     /locus_tag="Smed_4107"
                     /note="PFAM: dienelactone hydrolase;
                     KEGG: sme:SMb20022 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase"
                     /protein_id="YP_001312847.1"
                     /db_xref="GI:150376251"
                     /db_xref="InterPro:IPR002925"
                     /db_xref="GeneID:5318996"
                     /translation="MATVILFHSVYGLRPFERAVAERLAVAGHEVFTPDLYEGRVASS
                     IDEGFAIKEEIGWRALCERAERAVAGLPADAVLGGFSMGAAVAASLWPKRPETAGVLF
                     LHSIAEIPANARPGVPVQVHLADPDVFEPADEVTAWRSAAETTPIDLEVFTYAGAGHL
                     YTDATLPDYDSEAAHLTWSRVERCLAAL"
     misc_feature    complement(572701..573171)
                     /locus_tag="Smed_4107"
                     /note="Alpha/beta hydrolase family; Region: Abhydrolase_5;
                     pfam12695"
                     /db_xref="CDD:221718"
     gene            complement(573413..573784)
                     /locus_tag="Smed_4108"
                     /db_xref="GeneID:5318997"
     CDS             complement(573413..573784)
                     /locus_tag="Smed_4108"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312848.1"
                     /db_xref="GI:150376252"
                     /db_xref="GeneID:5318997"
                     /translation="MPFCPRLFVGCAPGQWTSPNCHPGARGSQSGAPQPHLYRSATLA
                     WITTTSGQIDLKSRTSSVQQVETRRPNPAFPVIILDPYSSACHKHRKRGADERLRDKQ
                     GMRLKSPTAANYVGTIRRAKR"
     gene            complement(573829..574296)
                     /locus_tag="Smed_4109"
                     /db_xref="GeneID:5318998"
     CDS             complement(573829..574296)
                     /locus_tag="Smed_4109"
                     /note="PFAM: regulatory protein AsnC/Lrp family;
                     KEGG: sme:SMb20021 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="AsnC family transcriptional regulator"
                     /protein_id="YP_001312849.1"
                     /db_xref="GI:150376253"
                     /db_xref="InterPro:IPR000485"
                     /db_xref="GeneID:5318998"
                     /translation="MNSFNLDAIDRKILRILQDRGDISHAAIAEAVGASPASCWRRIK
                     ALETAGVLVKTVSLVDPDLVGRGLNVFCQVRMKSHDPLARRNFERFVESHEEVLECYS
                     MSGDWDYLLRVLVADVADYERLLMRGILTHEAVANSSSHFALKSVKYSTAVPV"
     misc_feature    complement(573835..574296)
                     /locus_tag="Smed_4109"
                     /note="Transcriptional regulators [Transcription]; Region:
                     Lrp; COG1522"
                     /db_xref="CDD:224439"
     misc_feature    complement(<574135..574278)
                     /locus_tag="Smed_4109"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cd00090"
                     /db_xref="CDD:238042"
     misc_feature    complement(order(574135..574137,574153..574158,
                     574162..574167,574174..574179,574183..574194,
                     574219..574227,574267..574275))
                     /locus_tag="Smed_4109"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238042"
     misc_feature    complement(order(574216..574218,574225..574227))
                     /locus_tag="Smed_4109"
                     /note="putative Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    complement(573859..574083)
                     /locus_tag="Smed_4109"
                     /note="AsnC family; Region: AsnC_trans_reg; pfam01037"
                     /db_xref="CDD:216258"
     gene            574417..576495
                     /locus_tag="Smed_4110"
                     /db_xref="GeneID:5318545"
     CDS             574417..576495
                     /locus_tag="Smed_4110"
                     /note="PFAM: dehydrogenase E1 component; Transketolase
                     central region; Transketolase domain protein;
                     KEGG: sme:SMb20020 putative pyruvate dehydrogenase E1
                     component,alpha and beta subunits protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase domain-containing protein"
                     /protein_id="YP_001312850.1"
                     /db_xref="GI:150376254"
                     /db_xref="InterPro:IPR001017"
                     /db_xref="InterPro:IPR005475"
                     /db_xref="InterPro:IPR005476"
                     /db_xref="GeneID:5318545"
                     /translation="MTQAALKKDRRNAPDENIDWKRVVQLLLLSRELDEMEERRLVPE
                     KKVLYQFSARGHDMAQILLGLQLTGRHDAACGYYRSRPLLLALGVDPADALGSAMGRA
                     GGYSDGRDIGVVFNYPNPDGASALPMCGGVGSQYTPTAGWAQAITYFNQVLGNEEYRE
                     DIAVVLGGDGSVASNGFWSALTIATTQGLPLLFYIEDNGFGISVPSSFQTPEGNIAGN
                     LAGWKNLTVLDGDGSDPAEAARLTKSAVERVREGRMPVLLRLEVPRLEGHSFQDTQAY
                     KSEELVKSEWAHDPLPRLRDHLVPAMLTAEEWNDAARAAKREAERARIEAESRPVADP
                     ETVTGNVFFEGRMQIMGGQHCAGYCPPETTERATSAGERINMVTAIRRTLDHEMSVNE
                     RVVLFGEDIGAKGGVHAVTLGLQEKYGVVRVFDTSLSEEGIIGRAVGMALAGLVPVPE
                     IQFRKYAEPAIEQLNDCGTIRWRTSNRFAAPIIVRMAGGFFKCGDPWHSQTNEVAFVH
                     QPGWKIAVPSNAEDAVGLLRTALRGNDPVIFFEHRAMLDHPWARRPYPGDAFGLPFGK
                     AKFTREGGDITIVTWGAMVPRCEAAAEGISADVIDLRSLMPWDSEAVIASVRRTRRCL
                     IVHEDLGTAGFGAEIAAVVAQEAFIDLDAPISRLTMPDIPSPHNPVLLDWVVPSPERI
                     RKKINDLLEF"
     misc_feature    574423..575490
                     /locus_tag="Smed_4110"
                     /note="Pyruvate/2-oxoglutarate dehydrogenase complex,
                     dehydrogenase (E1) component, eukaryotic type, alpha
                     subunit [Energy production and conversion]; Region: AcoA;
                     COG1071"
                     /db_xref="CDD:223997"
     misc_feature    574492..575346
                     /locus_tag="Smed_4110"
                     /note="Thiamine pyrophosphate (TPP) family, E1 of
                     PDC_ADC_BCADC subfamily, TPP-binding module; composed of
                     proteins similar to the E1 components of the human
                     pyruvate dehydrogenase complex (PDC), the acetoin
                     dehydrogenase complex (ADC) and the branched chain...;
                     Region: TPP_E1_PDC_ADC_BCADC; cd02000"
                     /db_xref="CDD:238958"
     misc_feature    order(574558..574560,574714..574716,574804..574809,
                     574924..574926,574930..574941,574948..574950,
                     574960..574962,574972..574974,575017..575028,
                     575068..575070,575086..575088,575239..575241)
                     /locus_tag="Smed_4110"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238958"
     misc_feature    order(574648..574653,574804..574806,574810..574812,
                     574918..574929,575008..575010,575014..575016,
                     575218..575220)
                     /locus_tag="Smed_4110"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238958"
     misc_feature    order(574789..574791,574795..574797,574801..574803,
                     574816..574818,574825..574830,574837..574842,
                     574846..574851,574858..574860,574939..574944,
                     574960..574965,574972..574974)
                     /locus_tag="Smed_4110"
                     /note="heterodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238958"
     misc_feature    order(575203..575223,575227..575229,575230..575256,
                     575278..575286)
                     /locus_tag="Smed_4110"
                     /note="phosphorylation loop region [posttranslational
                     modification]"
                     /db_xref="CDD:238958"
     misc_feature    575533..576492
                     /locus_tag="Smed_4110"
                     /note="Pyruvate/2-oxoglutarate dehydrogenase complex,
                     dehydrogenase (E1) component, eukaryotic type, beta
                     subunit [Energy production and conversion]; Region: AcoB;
                     COG0022"
                     /db_xref="CDD:223101"
     misc_feature    575551..576045
                     /locus_tag="Smed_4110"
                     /note="Pyrimidine (PYR) binding domain of the beta
                     subunits of the E1 components of human pyruvate
                     dehydrogenase complex (E1- PDHc) and related proteins;
                     Region: TPP_PYR_E1-PDHc-beta_like; cd07036"
                     /db_xref="CDD:132919"
     misc_feature    order(575590..575592,575596..575598,575614..575616,
                     575680..575682,575689..575691,575695..575712,
                     575719..575724,575728..575736,575791..575793,
                     575800..575805,575827..575832,575896..575898,
                     575905..575907,575950..575955,576016..576021)
                     /locus_tag="Smed_4110"
                     /note="alpha subunit interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:132919"
     misc_feature    order(575611..575613,575698..575700,575704..575706,
                     575782..575784,575791..575793)
                     /locus_tag="Smed_4110"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132919"
     misc_feature    order(575614..575616,575689..575691,575695..575706,
                     575788..575793,575797..575799,575809..575811,
                     575821..575823,575830..575832,575896..575898,
                     575902..575907,575929..575931,575935..575940,
                     575944..575946)
                     /locus_tag="Smed_4110"
                     /note="heterodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:132919"
     misc_feature    576109..576462
                     /locus_tag="Smed_4110"
                     /note="Transketolase, C-terminal domain; Region:
                     Transketolase_C; pfam02780"
                     /db_xref="CDD:217227"
     gene            576499..577659
                     /locus_tag="Smed_4111"
                     /db_xref="GeneID:5318546"
     CDS             576499..577659
                     /locus_tag="Smed_4111"
                     /EC_number="2.3.1.61"
                     /note="PFAM: biotin/lipoyl attachment domain-containing
                     protein; catalytic domain of components of various
                     dehydrogenase complexes; E3 binding domain protein;
                     KEGG: sme:SMb20019 putative dihydrolipoamide
                     succinyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="YP_001312851.1"
                     /db_xref="GI:150376255"
                     /db_xref="InterPro:IPR000089"
                     /db_xref="InterPro:IPR001078"
                     /db_xref="InterPro:IPR003016"
                     /db_xref="InterPro:IPR004167"
                     /db_xref="GeneID:5318546"
                     /translation="MVDLIDIQAPLEQEGTKAVVRNWLREIGEKVKSGDPLVELETDK
                     VTQEVAAPADGVLLEILMRNGDDARPGAVLGRIGSELAGGEDAPHYSPAVRRAAEEYG
                     FDPATITGTGRDGRVTRGDMDRAFAARQAGGASPEPRPDGGRGEPESSRIPHSSMRAA
                     IAEHMLNSVMTAPHVTAVFEADFSAVTRHRDEHRKKLAARGVNLSYTAYVVLASLAAM
                     RAVPEVNSRWHEDALETFDDINIGVGISLGGKGLVVPVIRRAQNLSLAEIAARIQDLT
                     TRARSNALSPADVTGGTFTISNHGVSGSLLATPIIINQPQSAILGVGKLDKRVVVREV
                     DGIDTIQIRPMAYVSLTIDHRALDGHHTNAWLTEFVRVLESWPGEATKNGLA"
     misc_feature    576511..577641
                     /locus_tag="Smed_4111"
                     /note="Pyruvate/2-oxoglutarate dehydrogenase complex,
                     dihydrolipoamide acyltransferase (E2) component, and
                     related enzymes [Energy production and conversion];
                     Region: AceF; COG0508"
                     /db_xref="CDD:223582"
     misc_feature    576511..576729
                     /locus_tag="Smed_4111"
                     /note="Lipoyl domain of the dihydrolipoyl acyltransferase
                     component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid
                     dehydrogenase multienzyme complexes, like pyruvate
                     dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH)
                     and branched-chain 2-oxo acid...; Region: lipoyl_domain;
                     cd06849"
                     /db_xref="CDD:133458"
     misc_feature    order(576598..576600,576619..576636,576646..576648)
                     /locus_tag="Smed_4111"
                     /note="E3 interaction surface; other site"
                     /db_xref="CDD:133458"
     misc_feature    576628..576630
                     /locus_tag="Smed_4111"
                     /note="lipoyl attachment site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133458"
     misc_feature    576991..577620
                     /locus_tag="Smed_4111"
                     /note="2-oxoacid dehydrogenases acyltransferase (catalytic
                     domain); Region: 2-oxoacid_dh; pfam00198"
                     /db_xref="CDD:215782"
     gene            577735..578757
                     /locus_tag="Smed_4112"
                     /db_xref="GeneID:5318547"
     CDS             577735..578757
                     /locus_tag="Smed_4112"
                     /note="KEGG: sme:SMb20018 putative sugar ABC transporter
                     periplasmic sugar-binding protein ABC transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sugar ABC transporter periplasmic
                     sugar-binding protei"
                     /protein_id="YP_001312852.1"
                     /db_xref="GI:150376256"
                     /db_xref="GeneID:5318547"
                     /translation="MRKLIAFALGTVASIVIAASAHAETIKIGLSNGWVGSEWRTQMI
                     DEAKAAAAKWKEKGVDVEVSVQSANVDVPGQIAHIRNFIAEGVNAIIVNPNSPTAFDP
                     IFSQAKEAGILVIATDAEVSSPDAIYVGIDQTAWGAAGGKWLAETLGGKGKVVAINGV
                     AGHPANEMRVAGYKSVFKDHPDIQVVNEVNANWDQAQGQQAMQNILATYPDINGVLVQ
                     DGMAAGAWKSIMDAGKTGQIAATGEIRKDFIDLWIKQKLNSGATVNPPGVMASALNVA
                     VLMLQGKELKEPAKAGQYGNALYLPIPFIDSKNLEEAAKQLEGKPGYYSYTSSLSIEE
                     AEALFK"
     sig_peptide     577735..577806
                     /locus_tag="Smed_4112"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.993 at
                     residue 24"
     misc_feature    577813..578649
                     /locus_tag="Smed_4112"
                     /note="Periplasmic sugar-binding component of
                     uncharacterized ABC-type transport systems that are
                     members of the pentose/hexose sugar-binding protein family
                     of the type I periplasmic binding protein superfamily;
                     Region: PBP1_ABC_sugar_binding_like_1; cd06300"
                     /db_xref="CDD:107295"
     misc_feature    577816..578586
                     /locus_tag="Smed_4112"
                     /note="Periplasmic binding protein domain; Region:
                     Peripla_BP_4; pfam13407"
                     /db_xref="CDD:222108"
     misc_feature    order(577849..577851,578086..578088,578239..578241,
                     578461..578463,578521..578523)
                     /locus_tag="Smed_4112"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107295"
     gene            578954..580510
                     /locus_tag="Smed_4113"
                     /db_xref="GeneID:5318548"
     CDS             578954..580510
                     /locus_tag="Smed_4113"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20017 putative sugar ABC transporter
                     ATP-binding protein ABC transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312853.1"
                     /db_xref="GI:150376257"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318548"
                     /translation="MRIGGEPPQTEANGQISMSKLKLSGVSKAYGATLALRRGDLEVM
                     AGEVHVLMGSNGSGKSTLCKIIAGSVRPDSGRILVDDQPVTITGPRSARAHGIGIFYQ
                     ELSLAAHRSVGENISLGRLPVKAGVFVDRSELRQRAARYIGLFDGVSGEEFSAEALVG
                     SLRPDQRQLVEIMKALASEAPLLIFDEPTSALDRAQVERFFEILRDLKRRGRGIVFIS
                     HRMDEIKAIGDRVTIIRDGETITTLNLNDTDPATVIRLMVGGAGDMPASQSSVPAVVD
                     AERGAALTVRNLSGRGFSDVSFEVARGEILGFGGLHGQGQSAVLRGIFGAGAVTSGKI
                     LIGEESFDASGPRKAIRCGCAYVSGDRARDGVISGRPIIENVTPIHYLRDRLMIARPR
                     KLRHKVAPALQSMQTKFASLFHPISSLSGGNQQKVIIARWLIDRPDVLLLDDPTKGID
                     LSAKADLFALIRQLAADGLGIVLYSSEDAELLGNANRILVFNGGSVSRELTGADRTRY
                     NLYQAAYEAA"
     misc_feature    579002..580498
                     /locus_tag="Smed_4113"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    579014..579667
                     /locus_tag="Smed_4113"
                     /note="ATP-binding cassette domain of the drug resistance
                     transporter and related proteins, subfamily A; Region:
                     ABC_DR_subfamily_A; cd03230"
                     /db_xref="CDD:213197"
     misc_feature    579110..579133
                     /locus_tag="Smed_4113"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213197"
     misc_feature    order(579119..579124,579128..579136,579257..579259,
                     579509..579514,579608..579610)
                     /locus_tag="Smed_4113"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213197"
     misc_feature    579248..579259
                     /locus_tag="Smed_4113"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213197"
     misc_feature    order(579302..579310,579449..579466)
                     /locus_tag="Smed_4113"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213197"
     misc_feature    579497..579514
                     /locus_tag="Smed_4113"
                     /note="Walker B; other site"
                     /db_xref="CDD:213197"
     misc_feature    579521..579532
                     /locus_tag="Smed_4113"
                     /note="D-loop; other site"
                     /db_xref="CDD:213197"
     misc_feature    579596..579616
                     /locus_tag="Smed_4113"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213197"
     misc_feature    579794..580441
                     /locus_tag="Smed_4113"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            580511..581503
                     /locus_tag="Smed_4114"
                     /db_xref="GeneID:5318549"
     CDS             580511..581503
                     /locus_tag="Smed_4114"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20016 putative sugar ABC transporter permease
                     protein ABC transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001312854.1"
                     /db_xref="GI:150376258"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318549"
                     /translation="MAETATVPSYRRAGGIGRVLERYPFLPALVIVVALLFLNGFFSP
                     NSLSFRALTGLLSTYMALILLSIAQTYVVYAGDIDLSAGAILSLVNVAIVVLMERWGG
                     GAGAVLLALAMGLLLGLVCGLVNGLVVAALRLQAIVATFATSIFFTGLALYILPVAGT
                     PAPALFWRAYGGRFFGVPFVFYILAVLAILLAVLSRTRLVTQLLAVGDDPQAAYQTGL
                     PVVATRVKGYVLCGLFSALAAFCITGDTASGDPLVGGKMTLYSVAAVVLGGSALSGGW
                     GTVVGSLLGALTIALVNSVVFFMGTPSEWQNFVQGLAILLVLMAGVLAGRRGRS"
     misc_feature    580694..581470
                     /locus_tag="Smed_4114"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    <580916..581464
                     /locus_tag="Smed_4114"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    581141..581197
                     /locus_tag="Smed_4114"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            581500..582456
                     /locus_tag="Smed_4115"
                     /db_xref="GeneID:5318550"
     CDS             581500..582456
                     /locus_tag="Smed_4115"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20015 putative sugar ABC transporter permease
                     protein ABC transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001312855.1"
                     /db_xref="GI:150376259"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318550"
                     /translation="MSRINSFLRQPIVVALVLIVFLLYLGEALSPGFATGGQILRLLI
                     VASLLGIIAAGQNVVILGGREGIDLSVGGVVSLSAIIAGNVMNGADGGILPAVGACLA
                     AGAFFGLLNGLGVTLLRIPPLVMTLGMLGVLQGLLVVIRMGIPSGQAAPALSRFVTQP
                     FAYGIPGIIWLWIMIGIVMALMLNRTVFGHRIYAIGSNEHAAYMAGVPVGIIRIALFV
                     ISGMFAAIAGLCLLGYSGTSFANVGEQYMLPSIIAVVFGGTSLAGGKGGYTGTMAGAV
                     LLVILQSILTTINIEESGRQMVFGATLLLLMMFYGRGRAMRA"
     misc_feature    581611..582264
                     /locus_tag="Smed_4115"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    581635..582429
                     /locus_tag="Smed_4115"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    582097..582153
                     /locus_tag="Smed_4115"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            582453..583457
                     /locus_tag="Smed_4116"
                     /db_xref="GeneID:5318551"
     CDS             582453..583457
                     /locus_tag="Smed_4116"
                     /EC_number="5.1.1.1"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: sme:SMb20014 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="YP_001312856.1"
                     /db_xref="GI:150376260"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318551"
                     /translation="MKNRPKIKDIAEKAGVSVATVSRALADSALVTAETRQRVHDLAR
                     ELDYRPNVSARNLRTRKSMAVLMVVRDVGNPFYLEILKGVEATAREAGYAVLMGNTEN
                     DPARETEYFDMLRDGHADGMILMTGKLPPSGGWTHLAVVVALEMIEGSGLPHVQVDNV
                     AAARGAVEHLISLGHRRVAHISGPVPEPMSVYRREGYRLAMRDAGLEIPRGYEARGDF
                     LIESGERCCRSLFSLSDPPTALFVANDEMAYGAVHQLRRMGRDVPRDVSVVGFDDLYL
                     SKAFYPPLTTVGQPRAEIGRTAMAVLLGILAGDGAYGIQPIVLPTTLKVRGSTAPPRF
                     "
     sig_peptide     582453..582533
                     /locus_tag="Smed_4116"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.799) with cleavage site probability 0.676 at
                     residue 27"
     misc_feature    582465..583451
                     /locus_tag="Smed_4116"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    582474..582629
                     /locus_tag="Smed_4116"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(582474..582476,582498..582512,582516..582521,
                     582528..582530,582543..582548,582555..582557,
                     582594..582596,582603..582605,582612..582617,
                     582621..582626)
                     /locus_tag="Smed_4116"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    582594..582623
                     /locus_tag="Smed_4116"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    582642..583436
                     /locus_tag="Smed_4116"
                     /note="Ligand-binding domain of an uncharacterized
                     transcription regulator from Actinobacillus succinogenes
                     and its close homologs from other bacteria; Region:
                     PBP1_LacI_like_6; cd06284"
                     /db_xref="CDD:107279"
     misc_feature    order(582642..582644,582705..582707,582732..582734,
                     582741..582743,582747..582749,582804..582806,
                     583110..583112,583209..583211)
                     /locus_tag="Smed_4116"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107279"
     misc_feature    order(582672..582674,583029..583031,583266..583268,
                     583317..583319)
                     /locus_tag="Smed_4116"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107279"
     gene            583514..584758
                     /locus_tag="Smed_4117"
                     /db_xref="GeneID:5318552"
     CDS             583514..584758
                     /locus_tag="Smed_4117"
                     /note="PFAM: oxidoreductase domain protein;
                     KEGG: sme:SMb20013 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain-containing protein"
                     /protein_id="YP_001312857.1"
                     /db_xref="GI:150376261"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="GeneID:5318552"
                     /translation="MSTLPKQTLRIGFVGTGFIAHFHLNSLIGVRNVEVTGVYSRSAA
                     NRERFVGEAEALDLGRCRAHDSLESLFSAADIDAIWILSPNYTRLDVMRTLHREIKAG
                     RSTIFAVACEKPLARTVAEAREMLHLAEDAGLNHGYLENQVFCTPVLRGKEIIWRRAA
                     STTGRPYLARAAEEHAGPHEPWFWQGDKQGGGVLSDMMCHSVEVARHLLTAPGAPRNS
                     LKVKSVNGTVANLKWTRAGYADQLRRRFGEDVDYRRRPSEDFARATVTLEDEEGNELM
                     IEATTSWAYVGAGLRIQLELLGPEYALEYNSLGTGLKIFLSRAVQGSEGEDLVEKQNA
                     EQGLMPVLEDEAGVYGYTDENRHMVESFRKGVKPIETFDDGLAVVEILMGLYRSAEIG
                     ATLHFPAPELENYVPVVARVGA"
     misc_feature    583532..584698
                     /locus_tag="Smed_4117"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:223745"
     misc_feature    583538..583915
                     /locus_tag="Smed_4117"
                     /note="Oxidoreductase family, NAD-binding Rossmann fold;
                     Region: GFO_IDH_MocA; pfam01408"
                     /db_xref="CDD:201778"
     misc_feature    583967..>584149
                     /locus_tag="Smed_4117"
                     /note="Oxidoreductase family, C-terminal alpha/beta
                     domain; Region: GFO_IDH_MocA_C; pfam02894"
                     /db_xref="CDD:217272"
     gene            complement(584725..585632)
                     /locus_tag="Smed_4118"
                     /pseudo
                     /db_xref="GeneID:5318553"
     gene            complement(585614..585913)
                     /locus_tag="Smed_4119"
                     /db_xref="GeneID:5318554"
     CDS             complement(585614..585913)
                     /locus_tag="Smed_4119"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312858.1"
                     /db_xref="GI:150376262"
                     /db_xref="GeneID:5318554"
                     /translation="MLQSRPQIPPDRLNAPSVVAGTPFVRECQAAAQRCGRRCMGEPQ
                     RLFNAPAFMDAGEHPGSEGVVGPVLLFGNGDGQQNHAFPSRVTAMAKAGQCTALM"
     gene            586006..588549
                     /locus_tag="Smed_4120"
                     /db_xref="GeneID:5319313"
     CDS             586006..588549
                     /locus_tag="Smed_4120"
                     /note="PFAM: NAD-dependent epimerase/dehydratase;
                     short-chain dehydrogenase/reductase SDR; 3-beta
                     hydroxysteroid dehydrogenase/isomerase;
                     dTDP-4-dehydrorhamnose reductase; Vitamin K epoxide
                     reductase; Male sterility domain;
                     KEGG: sme:SMb20012 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin K epoxide reductase"
                     /protein_id="YP_001312859.1"
                     /db_xref="GI:150376263"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR012932"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5319313"
                     /translation="MPKDANQPTILITGSNGFLGQAIAHRLRDRYRVIGLDLSPPKGR
                     SETEETINLDITSDTSVREAIETARKRSSGRIASVIHLAAYYDTTGKDNPKYDAVNVE
                     GTRRLLKALQDLPTEQFIYASTLLVQAPSPAKATRINENSPLDPAWAYPKSKAETEAV
                     IAKERGAIRTVILRLAGVYDEDCRAAFIAQQIARIFERRPTAYLFSGDLEAGQPYLHK
                     DDLVEAFVRAVDRRDELPDDCVFLIGEEETFSYGELQKRIGQLVHGEDWCTLSLPKSL
                     AKPGAWMQTEVLDQDSEIKPWMIENSDDHYEIDISRARSRLGWQPLHSLGATLPEMIR
                     RLKQDPTDWYAKNKLEPSVVAASEPEIEQAEKRLAQPLERGKAEVEAAVDEHRLRTLW
                     APLANVALGLWLVASPMTLGLFDPVSVPVPPALGHEVAEPVIRNSRLATSEILSGLLV
                     AVFALSGMYRRWSYLQWITAALGVWIMLAPLVFWTTSAAAYAVDTLAGMLIVAFAVMI
                     PPTPGIGLRALSADDDRPLGWSYSPSSFTQRMPIVALAFVGLFVSRYLAAYQMGHVDG
                     LWDPFFGPDDAPVRNGSEAVVTSWVSKGFPIADAGLGAFAYALDILAGAIGDSRRWRT
                     MPWMVLLFGLLVVPLGAVSVSFIIIQPPLIGALCTLCIIQAAVTVVLIPYSIDEVLAT
                     TQYLWRATKAGEPFWRTFWKGGPALSEDQTPSPDLNRPASELLKEFVTGGVNFPWTLV
                     ASVLLGAALMITPVFFGTSPPLYHSDHVLGCVVILVAVTAMAEVVRPVRFLNVLLGAW
                     VASSPFLLDGSSAIGTLADVAMGLALIALSLPRGTRSEEHYGGWDRAIV"
     misc_feature    586027..586992
                     /locus_tag="Smed_4120"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    586033..587043
                     /locus_tag="Smed_4120"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    order(586045..586047,586051..586056,586060..586062,
                     586108..586116,586249..586257,586369..586377,
                     586453..586455,586465..586467,586528..586539)
                     /locus_tag="Smed_4120"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    order(586303..586305,586375..586377,586453..586455,
                     586465..586467)
                     /locus_tag="Smed_4120"
                     /note="active site"
                     /db_xref="CDD:187535"
     misc_feature    587587..588114
                     /locus_tag="Smed_4120"
                     /note="Vitamin K epoxide reductase family in bacteria;
                     Region: VKOR_2; cd12919"
                     /db_xref="CDD:240602"
     misc_feature    order(587713..587715,587752..587754,587770..587772,
                     587977..587979,587986..587988)
                     /locus_tag="Smed_4120"
                     /note="putative active site [active]"
                     /db_xref="CDD:240602"
     misc_feature    587977..587988
                     /locus_tag="Smed_4120"
                     /note="redox center [active]"
                     /db_xref="CDD:240602"
     gene            complement(588581..589360)
                     /locus_tag="Smed_4121"
                     /db_xref="GeneID:5319314"
     CDS             complement(588581..589360)
                     /locus_tag="Smed_4121"
                     /note="PFAM: zinc/iron permease;
                     KEGG: sme:SMb20011 zinc transporter, ZIP family"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc/iron permease"
                     /protein_id="YP_001312860.1"
                     /db_xref="GI:150376264"
                     /db_xref="InterPro:IPR003689"
                     /db_xref="GeneID:5319314"
                     /translation="MSNDLLIILGVASAAAVASPLGGMAAMALRPSSLVLSVAVGFAA
                     GVLMGTFAFEMMPTSVKLAGLALAVAGFLLGLALVYILDLYVNRWKMAGPEADQKEAV
                     DRLHRRRRPRGSNVAVLAGATSAEELIEGMTIGVGATFKPNVALIVGLAICIDNLSEG
                     MSIGELTLDEEPKSAKRRILGWTSLIGLSLFLSAMAGWFLLKGLAQPVTGFLFAMGAG
                     GMFYLTITDLVPEAESHQFQQSSAIANAAGFLLVMVLAEMS"
     misc_feature    complement(588596..589360)
                     /locus_tag="Smed_4121"
                     /note="Predicted divalent heavy-metal cations transporter
                     [Inorganic ion transport and metabolism]; Region: COG0428"
                     /db_xref="CDD:223505"
     sig_peptide     complement(589283..589360)
                     /locus_tag="Smed_4121"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.613 at
                     residue 26"
     gene            complement(589394..590461)
                     /gene="ligC"
                     /locus_tag="Smed_4122"
                     /db_xref="GeneID:5319315"
     CDS             complement(589394..590461)
                     /gene="ligC"
                     /locus_tag="Smed_4122"
                     /EC_number="6.5.1.1"
                     /note="catalyzes the ATP-dependent formation of a
                     phosphodiester at the site of a single-strand break in
                     duplex DNA; in mycobacteria LigC has weak intrinsic nick
                     joining activities and is not essential for growth"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA ligase"
                     /protein_id="YP_001312861.1"
                     /db_xref="GI:150376265"
                     /db_xref="InterPro:IPR000977"
                     /db_xref="InterPro:IPR012309"
                     /db_xref="InterPro:IPR012310"
                     /db_xref="GeneID:5319315"
                     /translation="MASPADGKPTKKAALSKAAEKTGGFPLPVGTAPMEARSAAELPG
                     GGPWQYEPKWDGFRCLAFKSGSDVDIRAKSGKPLGRFFPEILDLLHRLGPKTFVLDGE
                     LVIAIEGRLSFDALQMRLHPAASRVEKLSLETPAKLILFDMLADTDGAVLTGKPLRER
                     RARLEAFVKENAVAKMVELSPSTLDRREAGRWLTSWEAGATDGVVAKRLDGAYECGER
                     TMVKVKRLRTADCVVGGYRYESNGPLVGSLLLGLYDAEGLLNHVGFTATIADKERAAL
                     TRQLEALREPPGFTGKAPGGPSRWSSERSGEWEPVRPELVVEVRFDHVGNRRFRHGTK
                     LMRWRSDKDPRQCTFEQIAPP"
     misc_feature    complement(589397..590389)
                     /gene="ligC"
                     /locus_tag="Smed_4122"
                     /note="ATP-dependent DNA ligase; Reviewed; Region: ligC;
                     PRK08224"
                     /db_xref="CDD:236191"
     misc_feature    complement(589781..590368)
                     /gene="ligC"
                     /locus_tag="Smed_4122"
                     /note="Adenylation domain of Mycobacterium tuberculosis
                     LigC-like ATP-dependent DNA ligases; Region:
                     Adenylation_DNA_ligase_LigC; cd07905"
                     /db_xref="CDD:185714"
     misc_feature    complement(order(589796..589798,589802..589804,
                     589841..589843,589847..589849,589856..589858,
                     590039..590041,590123..590125,590156..590158,
                     590243..590245,590288..590296,590300..590311))
                     /gene="ligC"
                     /locus_tag="Smed_4122"
                     /note="active site"
                     /db_xref="CDD:185714"
     misc_feature    complement(order(589790..589792,589796..589798,
                     589856..589858,590090..590098,590105..590110,
                     590228..590230,590234..590236,590240..590248,
                     590288..590296,590303..590305))
                     /gene="ligC"
                     /locus_tag="Smed_4122"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:185714"
     misc_feature    complement(589415..589783)
                     /gene="ligC"
                     /locus_tag="Smed_4122"
                     /note="The Oligonucleotide/oligosaccharide binding
                     (OB)-fold domain of ATP-dependent DNA ligase LigC is a
                     DNA-binding module that is part of the catalytic core
                     unit; Region: OBF_DNA_ligase_LigC; cd07970"
                     /db_xref="CDD:153439"
     misc_feature    complement(order(589460..589462,589466..589471,
                     589475..589477,589652..589669,589673..589678,
                     589724..589726))
                     /gene="ligC"
                     /locus_tag="Smed_4122"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:153439"
     gene            complement(590487..592604)
                     /locus_tag="Smed_4123"
                     /db_xref="GeneID:5319316"
     CDS             complement(590487..592604)
                     /locus_tag="Smed_4123"
                     /EC_number="1.11.1.6"
                     /note="PFAM: Catalase domain protein;
                     KEGG: sme:SMb20007 probable catalase C protein"
                     /codon_start=1
                     /transl_table=11
                     /product="catalase"
                     /protein_id="YP_001312862.1"
                     /db_xref="GI:150376266"
                     /db_xref="InterPro:IPR002226"
                     /db_xref="InterPro:IPR010582"
                     /db_xref="InterPro:IPR011614"
                     /db_xref="GeneID:5319316"
                     /translation="MAKKPSAPNNTKPATIHDQKATRGNGGELHQIAEGDTPVLTTAQ
                     GGPVADDQNSLRAGERGPTLIEDFHFREKIFHFDHERIPERVVHARGYGVHGFFETYE
                     SLAAYTRADLFQRPGERTPAFVRFSTVAGSKGSFDLARDVRGFAVKIYTKEGNWDLVG
                     NNIPVFFIQDAIKFPDVIHSVKPEPDREFPQAQSAHDNFWDFISLTPESMHMIMWVMS
                     DRAIPRSFRFMEGFGVHTFRFVNAKDESTFVKFHWKPKLGLQSVVWNEAVKINGADPD
                     FHRRDMWQAIQSGNFPEWELHVQLFDQDFADKFDFDILDPTKIIPEEVLPTKPVGRLV
                     LDRMPENFFAETEQVAFMTQNVPPGIDFSDDPLLQGRNFSYLDTQLKRLGSPNFTHLP
                     INAPKCPFHNFQQDGHMAMRNPVGRANYQPNSWGEGPRESPVKGFRHFASEEQGPKLR
                     IRAESFADHYSQARQFFISQTPPEQRHIADALTFELSKVETPVIRERMVAHLLNIDET
                     LGKKVGHALGMETMPKPADAAVATRQDLDPSPALSIIQRGPKRFEGRKLGILATDGTD
                     AALLNALLQAVDTEKAAFELIAPKVGGFTASDGKRIAAHQMLDGGPSVLYDAVVLLAS
                     AEAVAELIDVATARDFVADAFAHCKYIGYVSAAVPLLERAGIAGLLDEGTIELTDAGS
                     AAAFLKELGKLRVWAREPSVKLK"
     misc_feature    complement(590496..592601)
                     /locus_tag="Smed_4123"
                     /note="hydroperoxidase II; Provisional; Region: katE;
                     PRK11249"
                     /db_xref="CDD:236886"
     misc_feature    complement(591054..592373)
                     /locus_tag="Smed_4123"
                     /note="Clade 2 of the heme-binding enzyme catalase;
                     Region: catalase_clade_2; cd08155"
                     /db_xref="CDD:163711"
     misc_feature    complement(order(591114..591116,591126..591128,
                     591132..591134,591141..591146,591333..591350,
                     591375..591383,591387..591389,591396..591398,
                     591402..591407,591417..591419,591429..591440,
                     591444..591449,591456..591464,591471..591476,
                     591483..591491,591498..591500,591507..591509,
                     591513..591515,591537..591542,591561..591563,
                     591570..591572,591576..591581,591585..591587,
                     591663..591665,591669..591671,591684..591689,
                     591756..591758,591765..591770,591777..591779,
                     591789..591794,591801..591803,591810..591812,
                     592002..592004,592011..592013,592035..592052,
                     592068..592070,592077..592079,592083..592097,
                     592140..592145,592200..592205,592347..592349,
                     592362..592364))
                     /locus_tag="Smed_4123"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:163711"
     misc_feature    complement(order(591480..591482,591492..591494,
                     592083..592085,592107..592109,592122..592124,
                     592224..592226,592341..592343))
                     /locus_tag="Smed_4123"
                     /note="heme binding pocket [chemical binding]; other site"
                     /db_xref="CDD:163711"
     misc_feature    complement(590523..590945)
                     /locus_tag="Smed_4123"
                     /note="Type 1 glutamine amidotransferase (GATase1)-like
                     domain found in at the C-terminal of several large
                     catalases; Region: GATase1_catalase; cd03132"
                     /db_xref="CDD:153226"
     misc_feature    complement(order(590679..590681,590688..590690,
                     590829..590837))
                     /locus_tag="Smed_4123"
                     /note="domain interactions; other site"
                     /db_xref="CDD:153226"
     gene            complement(592829..593749)
                     /locus_tag="Smed_4124"
                     /db_xref="GeneID:5319317"
     CDS             complement(592829..593749)
                     /locus_tag="Smed_4124"
                     /note="PFAM: pyridoxamine 5'-phosphate oxidase-related
                     FMN-binding;
                     KEGG: sme:SMb20006 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase-like
                     FMN-binding protein"
                     /protein_id="YP_001312863.1"
                     /db_xref="GI:150376267"
                     /db_xref="InterPro:IPR011576"
                     /db_xref="GeneID:5319317"
                     /translation="MEATILAPSPWHGGEVALQKRLGVDARMEEVGRRVLRDHLIEQH
                     REFYPLLPMVVLGSVDRNGDAWATLRAGEPGFLHAPDAKRLMVELPREPADPAEAGME
                     DGAPLALLGIDLGTRRRNRLNGKLRRHSRGFDLGVEQSFGNCPKYIQLRQVHFVRDPS
                     EPAALPPVSSFELDDAARALVENADTFFVATYAELGGGRQLDVSHRGGPVGFVHVGDD
                     GWLAIPDFTGNNFFNTLGNIAVNPRAGLTFPDFATGGLLQMTGEAELVSGPPRGVPLD
                     GAQRYWRFRPRRIVWRAEALAIRYDPARAG"
     misc_feature    complement(593159..593719)
                     /locus_tag="Smed_4124"
                     /note="Pyridoxine 5'-phosphate (PNP) oxidase-like
                     proteins; Region: PNPOx_like; cl00381"
                     /db_xref="CDD:241827"
     misc_feature    complement(<593006..593305)
                     /locus_tag="Smed_4124"
                     /note="Pyridoxine 5'-phosphate (PNP) oxidase-like
                     proteins; Region: PNPOx_like; cl00381"
                     /db_xref="CDD:241827"
     gene            complement(593942..594553)
                     /locus_tag="Smed_4125"
                     /db_xref="GeneID:5319318"
     CDS             complement(593942..594553)
                     /locus_tag="Smed_4125"
                     /note="PFAM: Glutathione S-transferase domain;
                     KEGG: sme:SMb20005 putative glutathione S-transferase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase domain-containing
                     protein"
                     /protein_id="YP_001312864.1"
                     /db_xref="GI:150376268"
                     /db_xref="InterPro:IPR004045"
                     /db_xref="InterPro:IPR004046"
                     /db_xref="GeneID:5319318"
                     /translation="MKLYHHPLSGHAHRVRLFLSLLGLEHELVHVDLASKEHKQEPFL
                     KLNPFGQLPVLDDGGTIVPDSNAILVYLAKKAGCTDWLPEDAGGAAAVQRWLSVAAGQ
                     IAHGPAQARLITLFQAPYRPEEVIPRSHAILKLIESELGGRSWIAAERPTIADVALYS
                     YVARAPEGDVDLHPYPEIRSWLARIEALPGFVEFQKTPAGLAA"
     misc_feature    complement(593945..594553)
                     /locus_tag="Smed_4125"
                     /note="Glutathione S-transferase [Posttranslational
                     modification, protein turnover, chaperones]; Region: Gst;
                     COG0625"
                     /db_xref="CDD:223698"
     misc_feature    complement(594335..594553)
                     /locus_tag="Smed_4125"
                     /note="Protein Disulfide Oxidoreductases and Other
                     Proteins with a Thioredoxin fold; Region:
                     Thioredoxin_like; cl00388"
                     /db_xref="CDD:241832"
     misc_feature    complement(593981..594280)
                     /locus_tag="Smed_4125"
                     /note="C-terminal, alpha helical domain of an unknown
                     subfamily 7 of Glutathione S-transferases; Region:
                     GST_C_7; cd03206"
                     /db_xref="CDD:198315"
     misc_feature    complement(order(594062..594064,594074..594076,
                     594083..594088,594095..594097,594254..594256,
                     594275..594277))
                     /locus_tag="Smed_4125"
                     /note="putative N-terminal domain interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:198315"
     misc_feature    complement(order(594149..594151,594251..594253,
                     594260..594265,594272..594277))
                     /locus_tag="Smed_4125"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:198315"
     misc_feature    complement(order(594062..594064,594071..594073,
                     594227..594232,594239..594244,594254..594256))
                     /locus_tag="Smed_4125"
                     /note="putative substrate binding pocket (H-site)
                     [chemical binding]; other site"
                     /db_xref="CDD:198315"
     gene            594671..595576
                     /locus_tag="Smed_4126"
                     /db_xref="GeneID:5319319"
     CDS             594671..595576
                     /locus_tag="Smed_4126"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb20004 putative GstR-like transcriptional
                     regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001312865.1"
                     /db_xref="GI:150376269"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5319319"
                     /translation="MDRWQAMRIFVQVVESGGFAPAAKALHMSPPSVTRAVAQLEGLI
                     GTRLLIRTTRSLKMTAAGEGYLADCRRILAEIAEAEANAAGSFTAPAGLLTVTAPALF
                     GRIHVLPVILDFLDAYPAMQVKTVFVDRVTNLVDEGLDVAIRIASLPASGLIARRIGS
                     VRQVLCGSPDYFARFGEPGSPHELAGHRIIGREGLFGHSEWLFGRDSSIRIPISPRLI
                     CNTNDAVLSAAVAGWGLSRFQSYQVEADIRAGRLKVALADYEREPVPIHIVHAEGRMV
                     SARVRAFVDFAAGRFLRHAGLSTEL"
     misc_feature    594677..595555
                     /locus_tag="Smed_4126"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    594680..594859
                     /locus_tag="Smed_4126"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    594944..595543
                     /locus_tag="Smed_4126"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     Region: PBP2_CrgA_like_2; cd08471"
                     /db_xref="CDD:176160"
     misc_feature    order(594974..594976,594986..594988,595103..595105,
                     595145..595147,595151..595153,595334..595336,
                     595385..595387,595466..595468)
                     /locus_tag="Smed_4126"
                     /note="putative effector binding pocket; other site"
                     /db_xref="CDD:176160"
     misc_feature    order(594977..594982,594992..594997,595001..595006,
                     595013..595015,595025..595027,595031..595051,
                     595232..595234,595316..595330,595349..595354,
                     595361..595363)
                     /locus_tag="Smed_4126"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176160"
     gene            complement(595583..596359)
                     /locus_tag="Smed_4127"
                     /db_xref="GeneID:5319320"
     CDS             complement(595583..596359)
                     /locus_tag="Smed_4127"
                     /EC_number="1.5.1.2"
                     /note="catalyzes the formation of L-proline from
                     pyrroline-5-carboxylate"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="YP_001312866.1"
                     /db_xref="GI:150376270"
                     /db_xref="InterPro:IPR004455"
                     /db_xref="GeneID:5319320"
                     /translation="MHIGFIGTGAITEAMVTGMIGSGLGIAEILVSPRNAEIAAQLAG
                     RFPLVRIARDNQEAVDASDVLFLAVRPQIAEEVIPRLKFRKGQTVVSVIAATDRTRLL
                     NWIDEEVDLTQAIPLPFVAEREGVTAIFPPSRDIAAIFEALGTPVECETKEEYDLLAV
                     ASALMATYLGILDQATGWFAEKGVGRDKARAYLAALFASLAQRAVRDGETPLDMLSRA
                     FSTPGGLNEQVLIDFDRGGGHRALTDALERVLLRVRGSGG"
     misc_feature    complement(595586..596359)
                     /locus_tag="Smed_4127"
                     /note="pyrroline-5-carboxylate reductase; Reviewed;
                     Region: PRK06476"
                     /db_xref="CDD:235812"
     misc_feature    complement(596078..596353)
                     /locus_tag="Smed_4127"
                     /note="NADP oxidoreductase coenzyme F420-dependent;
                     Region: F420_oxidored; pfam03807"
                     /db_xref="CDD:202773"
     gene            596763..597104
                     /locus_tag="Smed_4128"
                     /db_xref="GeneID:5319321"
     CDS             596763..597104
                     /locus_tag="Smed_4128"
                     /note="KEGG: sme:SMa1635 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312867.1"
                     /db_xref="GI:150376271"
                     /db_xref="GeneID:5319321"
                     /translation="MNFEQIVERSKPYAIGLVVGLIAAPIVGFNAGWITTTTASQKAV
                     ETARVDALTGICSSAAGRMATASSTDLAALKGYDNRAKRDELVAVIMADFQVPEDILD
                     KISTNCSRSLS"
     gene            complement(597614..597778)
                     /locus_tag="Smed_4129"
                     /db_xref="GeneID:5319322"
     CDS             complement(597614..597778)
                     /locus_tag="Smed_4129"
                     /note="KEGG: sme:SMa0121 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312868.1"
                     /db_xref="GI:150376272"
                     /db_xref="GeneID:5319322"
                     /translation="MIRFERKPDPQPTLKEVESKSAKQVREAAKEENKQPGAEPARRA
                     PQTVDDDRLI"
     gene            complement(597851..599485)
                     /gene="groEL"
                     /locus_tag="Smed_4130"
                     /db_xref="GeneID:5319272"
     CDS             complement(597851..599485)
                     /gene="groEL"
                     /locus_tag="Smed_4130"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; the rhizobia and high GC
                     gram-positive bacteria have multiple copies of the groEL
                     gene which are active under different environmental
                     conditions; the R. leguminosarum protein in this cluster
                     is transcribed under anaerobic conditions and is not
                     necessary for growth"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="YP_001312869.1"
                     /db_xref="GI:150376273"
                     /db_xref="InterPro:IPR001844"
                     /db_xref="InterPro:IPR002423"
                     /db_xref="InterPro:IPR012723"
                     /db_xref="GeneID:5319272"
                     /translation="MSAKEIIFSTEVRDRLLRGVELLNNAVKVTLGPKGRNVVIDRSY
                     GAPRITKDGVSVAKEIELEDKFENMGAQMVREVASKTNDLAGDGTTTATVLAASIFRE
                     GAKLVAAGMNPMDLKRGIDLAVTAVLAEIKLRATKVNSSSEIAQVGTIAANGDASVGE
                     MIAGAMEKVGNEGVITVEEARTADTELDVVEGMQFDRGYLSPYFVTNAEKMRVELDDP
                     YILIHEKKLGNLQTMLPILEAVVQSGKPLLIISEDVEGEALTTLVVNKLRGGLKIAAV
                     KSPGFGDRRKAMLQDIAVLTAGQMISEDIGIKLENVTLDMLGRARRVLIEKDTTTIID
                     GSGDKASIQACISQIKAQIEETTSDYDKEKLQERLAKLTGGVAVIRVGGATELEVKEK
                     KDRIDDALNATRAAVEEGIVAGGGVALLRAKSALASLTGENPEITAGIAIVRKALEAP
                     IRQIADNAGVEGSIVIGKLVDSSDQNQGFDAQTETYVDMIKAGIVDPAKVVRTALRDA
                     GSIAALLITAEAMVADIPEKNAAQNAGNGAMGGRGY"
     misc_feature    complement(597902..599485)
                     /gene="groEL"
                     /locus_tag="Smed_4130"
                     /note="chaperonin GroEL; Reviewed; Region: groEL;
                     PRK12850"
                     /db_xref="CDD:237231"
     misc_feature    complement(597914..599476)
                     /gene="groEL"
                     /locus_tag="Smed_4130"
                     /note="GroEL_like type I chaperonin. Chaperonins are
                     involved in productive folding of proteins. They share a
                     common general morphology, a double toroid of 2 stacked
                     rings, each composed of 7-9 subunits. The symmetry of type
                     I is seven-fold and they are found...; Region: GroEL;
                     cd03344"
                     /db_xref="CDD:239460"
     misc_feature    complement(order(597917..597937,597944..597946,
                     598109..598111,598328..598330,598334..598336,
                     598715..598717,598799..598801,598895..598897,
                     599258..599260,599267..599269,599279..599281,
                     599303..599305,599309..599311,599339..599341,
                     599345..599350,599363..599365,599369..599380,
                     599411..599413,599462..599464,599474..599476))
                     /gene="groEL"
                     /locus_tag="Smed_4130"
                     /note="ring oligomerisation interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239460"
     misc_feature    complement(order(597998..598000,598004..598006,
                     598124..598126,598241..598243,598292..598294,
                     599036..599038,599213..599215,599225..599227,
                     599387..599395))
                     /gene="groEL"
                     /locus_tag="Smed_4130"
                     /note="ATP/Mg binding site [chemical binding]; other site"
                     /db_xref="CDD:239460"
     misc_feature    complement(order(598085..598087,598094..598099,
                     598103..598105,598130..598132,598184..598186,
                     599159..599161))
                     /gene="groEL"
                     /locus_tag="Smed_4130"
                     /note="stacking interactions; other site"
                     /db_xref="CDD:239460"
     misc_feature    complement(order(598256..598261,598361..598363,
                     598907..598909,598928..598930,599063..599065))
                     /gene="groEL"
                     /locus_tag="Smed_4130"
                     /note="hinge regions; other site"
                     /db_xref="CDD:239460"
     gene            complement(599534..599850)
                     /locus_tag="Smed_4131"
                     /pseudo
                     /db_xref="GeneID:5319273"
     gene            complement(600107..601180)
                     /locus_tag="Smed_4132"
                     /db_xref="GeneID:5319274"
     CDS             complement(600107..601180)
                     /locus_tag="Smed_4132"
                     /note="PFAM: ABC transporter related; TOBE domain protein;
                     Transport-associated OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20002 probable lactose transport ATP-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312870.1"
                     /db_xref="GI:150376274"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005116"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5319274"
                     /translation="MSNLQLSQVRKSYGGLEVIKGVDLDIKSGEFVVFVGPSGCGKST
                     LLRMIAGLEEITSGELSIDEVRMNDVDPSKRGIAMVFQSYALYPHMTVRENMGFALRF
                     AGVPKAEIEKRVNEAADILELGTLLDRKPKQLSGGQRQRVAIGRAIVRHPKIFLFDEP
                     LSNLDAELRVHMRIEIARLHKQLATTIVYVTHDQVEAMTLADKIVVMRGGVVEQIGSP
                     LNLYDDPANLFVAGFIGSPKMNFLKGTTEIVEGRTYARLPDHGGLKIPISLEAIAPDT
                     PVTIGLRPEHFNEAGPAVLDLTIDMLEHLGGETFAYARHGNGALIVVETKNGRGLKAG
                     DRLAARFDPASALVFDGEGKRLR"
     misc_feature    complement(600116..601180)
                     /locus_tag="Smed_4132"
                     /note="glycerol-3-phosphate transporter ATP-binding
                     subunit; Provisional; Region: ugpC; PRK11650"
                     /db_xref="CDD:236947"
     misc_feature    complement(600533..601171)
                     /locus_tag="Smed_4132"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    complement(601052..601075)
                     /locus_tag="Smed_4132"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(order(600605..600607,600704..600709,
                     600935..600937,601049..601057,601061..601066))
                     /locus_tag="Smed_4132"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(600935..600946)
                     /locus_tag="Smed_4132"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(600752..600781)
                     /locus_tag="Smed_4132"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(600704..600721)
                     /locus_tag="Smed_4132"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(600686..600697)
                     /locus_tag="Smed_4132"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(600599..600619)
                     /locus_tag="Smed_4132"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(600134..600343)
                     /locus_tag="Smed_4132"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            complement(601177..603441)
                     /locus_tag="Smed_4133"
                     /db_xref="GeneID:5319275"
     CDS             complement(601177..603441)
                     /locus_tag="Smed_4133"
                     /note="PFAM: glycoside hydrolase family 2 immunoglobulin
                     domain protein beta-sandwich; glycoside hydrolase family 2
                     TIM barrel; glycoside hydrolase family 2 sugar binding;
                     KEGG: sme:SMb21655 probable beta-galactosidase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="YP_001312871.1"
                     /db_xref="GI:150376275"
                     /db_xref="InterPro:IPR006101"
                     /db_xref="InterPro:IPR006102"
                     /db_xref="InterPro:IPR006103"
                     /db_xref="InterPro:IPR006104"
                     /db_xref="GeneID:5319275"
                     /translation="MRSVTSFNDSWVFSAGFTAADAGTLQAGQPIRLPHNAIELPFNY
                     FDETCYQRAFTYQKVLAWRPDFSGREVSLVFDAAMADAVVYLNGEEIVAHKDGYTPIE
                     ARLTGRLREGDNLITVKIDGSENPEIPPFGGRIDYLTFAGIYRDVWLKITDPVSIANI
                     KIETRDVLSDARTVSVRCDLANPQGLSFTGAVSALLKDAAGDVLAEVAGETAGGGVTV
                     QMDGLKGLSLWDIDDPVLYEVEVELRTGRGSDRVAAHFGFRTAEFTNEGFRLNGRLLK
                     IRGLNRHQSFPYVGYAMGRTAQERDAEIMKHTLHCNLVRTSHYPQSKWFLDHCDRIGL
                     LVFEEIPGWQHIGGEAWKEEAILNVARMIERDWNHPSIVIWGVRINESQDSHDFYAKT
                     NRLARELDPTRQTGGVRYITDSEFLEDVYTMNDFILGNEELPGSNRPRTALRPQQECT
                     GLSRKVPYLITEFGGHMYPTKIYDQEQRQAEHVRRHLEVLNAAYGDPSISGAIGWCMF
                     DYNTHKDFGSGDRICYHGVMDMFREPKFAAYVYASQCDPSEEVVMKPVTFWARGERNI
                     GGVLPLIVLTNCDEVELKYGSLVKRIGPDRENYPHLPHPPVVIDHRHFTKDELGVWGM
                     KWESAEFTGFIDGKPVAGRRMVADPVPTTLEIEADGKTLRAGGRDSIRIMLRALDQAG
                     NVLPFLNDAVAIEVHGPARVVGPTRLVFQGGSTGFWLESTGAAGAIVVTAVSSRLGGV
                     KLELVAMAEGEWNA"
     misc_feature    complement(601282..603441)
                     /locus_tag="Smed_4133"
                     /note="Beta-galactosidase/beta-glucuronidase [Carbohydrate
                     transport and metabolism]; Region: LacZ; COG3250"
                     /db_xref="CDD:225789"
     misc_feature    complement(602983..603441)
                     /locus_tag="Smed_4133"
                     /note="Glycosyl hydrolases family 2, sugar binding domain;
                     Region: Glyco_hydro_2_N; pfam02837"
                     /db_xref="CDD:217248"
     sig_peptide     complement(603358..603441)
                     /locus_tag="Smed_4133"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.663) with cleavage site probability 0.612 at
                     residue 28"
     misc_feature    complement(602665..602979)
                     /locus_tag="Smed_4133"
                     /note="Glycosyl hydrolases family 2; Region:
                     Glyco_hydro_2; pfam00703"
                     /db_xref="CDD:216070"
     misc_feature    complement(601810..602661)
                     /locus_tag="Smed_4133"
                     /note="Glycosyl hydrolases family 2, TIM barrel domain;
                     Region: Glyco_hydro_2_C; pfam02836"
                     /db_xref="CDD:217247"
     gene            complement(603450..604265)
                     /locus_tag="Smed_4134"
                     /db_xref="GeneID:5319276"
     CDS             complement(603450..604265)
                     /locus_tag="Smed_4134"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21654 probable lactose uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001312872.1"
                     /db_xref="GI:150376276"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319276"
                     /translation="MNGIGRFAASAATYGFLGLMAFLSIFPFIWMVLGATNSSIDIIK
                     GKLLPGAAFATNVGNFFTLNVPLVFWNSAKIAILATVLTLAVSSLAGYGFEMFRSRGR
                     ERVYRAMLLTLMIPFAALMIPLFVIMGKAGLINTHIAVVLPSIGSAFVIFYFRQSTKA
                     FPSELRDAAKVDGLKEWQIFLFIYVPVMRSTYAAAFVIVFMTAWNNYLWPLIVLQTNE
                     TKTITLVISSLASAYYPDYGVVMVGTILATLPTLAVFFFMQRQFVQGMLGSVK"
     misc_feature    complement(603453..604265)
                     /locus_tag="Smed_4134"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     sig_peptide     complement(604161..604265)
                     /locus_tag="Smed_4134"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.785) with cleavage site probability 0.643 at
                     residue 35"
     misc_feature    complement(603510..604061)
                     /locus_tag="Smed_4134"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(603510..603515,603522..603527,
                     603534..603539,603543..603548,603555..603560,
                     603588..603593,603630..603635,603642..603653,
                     603672..603674,603681..603686,603726..603728,
                     603777..603779,603786..603791,603801..603803,
                     603807..603812,603819..603821,603825..603827,
                     603831..603836,603891..603893,603897..603902,
                     603909..603938,603942..603953,603981..603983,
                     603996..604001,604008..604013))
                     /locus_tag="Smed_4134"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(603636..603653,603891..603935))
                     /locus_tag="Smed_4134"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(603558..603560,603588..603590,
                     603597..603599,603633..603635,603849..603851,
                     603891..603893))
                     /locus_tag="Smed_4134"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(603705..603707,603717..603722,
                     603738..603776))
                     /locus_tag="Smed_4134"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(604262..605161)
                     /locus_tag="Smed_4135"
                     /db_xref="GeneID:5319277"
     CDS             complement(604262..605161)
                     /locus_tag="Smed_4135"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21653 probable lactose uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312873.1"
                     /db_xref="GI:150376277"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319277"
                     /translation="MALVRRAGIGRYYDVNGWLFVAPALGLIALFMIYPIAWSLWMSF
                     QSGRGMTMKFAGFANIVRLWNDPVFIKALTNTMTYFVVQVPIMILLALILASLLNNPR
                     LVGRGLFRTAIFLPCVSSLVAYSVLFKGMFATDGIVNSTLQAIGLVASPIPWLTHPFW
                     AKVLVILAITWRWTGYNMIFYLAALQNIDKSIYEVARIDGVPAWARFTHLTIPLLKPV
                     ILFTTIISTIGTLQLFDEVYNLTEGKGGPSNATLTLSLYIYNLTFRFMPNLGYAATVS
                     YVIVVLVALLAFVQFFAARERDR"
     misc_feature    complement(<604514..605110)
                     /locus_tag="Smed_4135"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cl00427"
                     /db_xref="CDD:241857"
     misc_feature    complement(604355..>604729)
                     /locus_tag="Smed_4135"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(604355..604357,604385..604387,
                     604394..604396,604448..604450,604667..604669,
                     604727..604729))
                     /locus_tag="Smed_4135"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(604520..604522,604532..604537,
                     604553..604591))
                     /locus_tag="Smed_4135"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(605247..606521)
                     /locus_tag="Smed_4136"
                     /db_xref="GeneID:5319278"
     CDS             complement(605247..606521)
                     /locus_tag="Smed_4136"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb21652 probable lactose uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312874.1"
                     /db_xref="GI:150376278"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5319278"
                     /translation="MDIQARAYLPRIAALALAGASFLGVSAAQAKEITIWCWDPNFNV
                     AIMKEAGDRYTKTHPDVTFNIVDFAKLDVEQKLQTGLSSGTADALPDIVLIEDYGAQK
                     YLQSFPGAFAPLSGTVDYSGFAPYKVELMTLDGEVYGMPFDSGVTGLYYRKDYLEAAG
                     FKPEDMQDLTWDRFIEIGKQVEAKTGKKMMGLDPNDAGLVRIIMQSAGQWYFDKEGKP
                     NITGNAALKAALETIGKIMQANIYKPANGWSDWVGTFTSGDVATVVTGVWITGTVKAQ
                     PDQSGNWGVAPIPALSIEGATHASNLGGSSWYVLESSEEKAEAIDFLNEIYAKDIDFY
                     QKILQDRGAVGSLLAARGGAAYEAADPFFGGEKVWQNFSEWLAKVPSVNYGIFTNEAD
                     LAVTAQLPAVTQGTPVDEVLKAIEAEIAGQIQ"
     sig_peptide     complement(606429..606521)
                     /locus_tag="Smed_4136"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.982 at
                     residue 31"
     misc_feature    complement(605250..606428)
                     /locus_tag="Smed_4136"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     misc_feature    complement(605532..606389)
                     /locus_tag="Smed_4136"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     gene            complement(606754..607833)
                     /locus_tag="Smed_4137"
                     /db_xref="GeneID:5319279"
     CDS             complement(606754..607833)
                     /locus_tag="Smed_4137"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: sme:SMb21650 putative transcriptional regulator,
                     LacI family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein LacI"
                     /protein_id="YP_001312875.1"
                     /db_xref="GI:150376279"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5319279"
                     /translation="MVTIKEIASAVGVSSATVSRVLNYDPTLSISTRKRQAIIETAEA
                     LNYATPRNRNRAAAQAVGSGLKIALVHFLDPAQELADPYYVGVRLGIESRCQALNSDV
                     VKVFLTGNTPEATILEGASGVVAVGHYYGDELEWLRRHSRHLVFADYAPAGDMEDTVL
                     SDVSQAMIRLLEAVHAMGYRRIGFIGWIDAFYGPDNIHSERRCHTYIDWMTKTGLFDP
                     ELCLVDPMTPDSGYRLAKAMLSKPNPPKILITCNDNMALGAYRAINEMGLRIPDDVAV
                     ASFNDIPVAQFLGPPLSTVKIPAELIGETAVDLLVERLSGREVAKKVVFGTEIIWRAS
                     TPAPTGAANPAEHMVPASSASEVPG"
     misc_feature    complement(606820..607830)
                     /locus_tag="Smed_4137"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    complement(606832..607638)
                     /locus_tag="Smed_4137"
                     /note="Ligand-binding domain of DNA transcription
                     repressor GalR which is one of two regulatory proteins
                     involved in galactose transport and metabolism; Region:
                     PBP1_GalR; cd01544"
                     /db_xref="CDD:107257"
     misc_feature    complement(order(607039..607044,607051..607053,
                     607063..607065,607147..607149,607477..607485,
                     607498..607500,607507..607509,607522..607524,
                     607528..607542,607555..607560,607564..607569,
                     607576..607584,607636..607638))
                     /locus_tag="Smed_4137"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:107257"
     misc_feature    complement(order(606943..606945,606994..606996,
                     607156..607158,607228..607230,607351..607353,
                     607390..607392,607456..607458,607573..607575,
                     607582..607587))
                     /locus_tag="Smed_4137"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107257"
     gene            complement(607902..608837)
                     /locus_tag="Smed_4138"
                     /db_xref="GeneID:5319280"
     CDS             complement(607902..608837)
                     /locus_tag="Smed_4138"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type; AraC protein arabinose-binding/dimerisation;
                     KEGG: sme:SMb21649 alpha-galactoside utilization
                     transcriptional regulator, AraC family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="YP_001312876.1"
                     /db_xref="GI:150376280"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="InterPro:IPR003313"
                     /db_xref="GeneID:5319280"
                     /translation="MGNSVLRHLMDRGPAMRTVSLPRGRQSLHTMPTSTGYEIRTDAS
                     YDWDGRKRGQTPFTVLQHTIGGAGNLRYESRSFRVSPGETLLLLVPHNHRYWLEDGGR
                     WEFFWISMNGEEALRIHRAILAVTGPVLKLQPETIEHLADCSLRLITGGETPGSASAI
                     AYEAAMALYDDVFGSHPVLSDEYRKMQHVIDHILSNLDKPLPVEELAGISGLSRAHFS
                     RVFAASEGMPPAEFVLQKRLQRAVKLLTKTADLPVKEVAILSGFEDPNYFAKVFRRVF
                     GASPTEFRTTGMYASVPATGRPGGVDASVSKLARG"
     misc_feature    complement(608391..608732)
                     /locus_tag="Smed_4138"
                     /note="AraC-like ligand binding domain; Region:
                     AraC_binding; pfam02311"
                     /db_xref="CDD:145456"
     misc_feature    complement(607986..608240)
                     /locus_tag="Smed_4138"
                     /note="helix_turn_helix, arabinose operon control protein;
                     Region: HTH_ARAC; smart00342"
                     /db_xref="CDD:197666"
     misc_feature    complement(607983..608096)
                     /locus_tag="Smed_4138"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     gene            609032..610504
                     /locus_tag="Smed_4139"
                     /db_xref="GeneID:5319281"
     CDS             609032..610504
                     /locus_tag="Smed_4139"
                     /note="PFAM: glycoside hydrolase family 4;
                     KEGG: sme:SMb21648 alpha-galactosidase (melibiase)
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="YP_001312877.1"
                     /db_xref="GI:150376281"
                     /db_xref="InterPro:IPR001088"
                     /db_xref="InterPro:IPR005829"
                     /db_xref="GeneID:5319281"
                     /translation="MASFKIAIIGAGSIGFTKKLFTDILSVPELRDVEFALTDLSEHN
                     LAMIKSILDRIVEANKLPTRVTATTDRRRALEGARYIISCVRVGGLEAYADDIRIPLK
                     YGVDQCVGDTICAGGILYGQRNIPVILDFCKDIREVAEPGAKFLNYANPMAMNSWAAI
                     EYGKVDTVGLCHGVQHGAEQIAEILGAGEGELDYICSGINHQTWFVDIRLGGRKIGKD
                     ELVAAFEAHPIFSQQEKLRIDVLKRFGVYSTESNGHLSEYLPWYRKRPDEISRWIDMS
                     DWIHGETGGYLRYSTETRNWFETEYPRFLEEASRPLETIKRSNEHASRILEALETGRV
                     YRGHFNVKNNGVITNLPADAIIESPGFVDRFGINMVAGITLPEACAATCIASINVQRM
                     SVHAAITGDIDLLKLAVLHDPLVGAICTPEEVWQMVDEMVVAQAEWLPQYAHAIDAAK
                     ERLARATVATREWKGAARREVRSIEEIRAEKEAAKLRAAG"
     misc_feature    609038..610360
                     /locus_tag="Smed_4139"
                     /note="alpha-galactosidase; Provisional; Region: PRK15076"
                     /db_xref="CDD:185035"
     misc_feature    609041..610327
                     /locus_tag="Smed_4139"
                     /note="Glycoside Hydrolases Family 4; Alpha-glucosidases
                     and alpha-galactosidases; Region:
                     GH4_alpha_glucosidase_galactosidase; cd05297"
                     /db_xref="CDD:133433"
     misc_feature    order(609065..609070,609146..609151,609161..609163,
                     609281..609289,609296..609301,609371..609373,
                     609410..609412,609473..609475,609479..609481,
                     609539..609541)
                     /locus_tag="Smed_4139"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:133433"
     misc_feature    order(609371..609373,609479..609481,609542..609544,
                     609632..609634,609782..609784,609791..609793)
                     /locus_tag="Smed_4139"
                     /note="sugar binding site [chemical binding]; other site"
                     /db_xref="CDD:133433"
     misc_feature    order(609542..609544,609632..609634)
                     /locus_tag="Smed_4139"
                     /note="divalent metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:133433"
     misc_feature    order(609599..609601,609608..609610,609656..609658,
                     609665..609667,610025..610027,610061..610063,
                     610118..610123,610127..610129,610133..610144)
                     /locus_tag="Smed_4139"
                     /note="putative tetramer (dimer of dimers) interface
                     [polypeptide binding]; other site"
                     /db_xref="CDD:133433"
     misc_feature    order(609761..609763,609797..609799,610157..610162,
                     610172..610174,610181..610183,610193..610195,
                     610202..610204,610214..610216,610232..610234,
                     610238..610240,610247..610252,610259..610264,
                     610277..610279,610283..610285,610289..610291,
                     610295..610297)
                     /locus_tag="Smed_4139"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:133433"
     gene            610706..612787
                     /locus_tag="Smed_4140"
                     /db_xref="GeneID:5319136"
     CDS             610706..612787
                     /locus_tag="Smed_4140"
                     /note="PFAM: extracellular solute-binding protein family
                     5;
                     KEGG: sme:SMb21647 alpha-galactoside ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312878.1"
                     /db_xref="GI:150376282"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="InterPro:IPR008162"
                     /db_xref="GeneID:5319136"
                     /translation="MKTHRSNRTAYLLIGISAFAVQAFASEPTIVPEQPPFPAQGKIT
                     YVSRESILEFKALPEYREPEWVTEKFVKAGKLPPLSERLPKEPMVFKAGNMPDGMGVY
                     GDVMRHVIGGRPEGWNYSAGQTQGWGGIDIGMFECLTRTAPLFQVEADDMEPLPNLAK
                     SWEWSEDGHKLTMHLIEGAKWSDGDPFDAEDVMFYWEDNVLDPSVSPLNGATPETFGE
                     GTTLKEVDKYTVEWTFKEAFPRQHLFAMAYGTFCPGPSHILKTKHPKYAGTTYNEYKN
                     GFPAEYLNLPVMGGWVPVAYRPDDIIVLRRNPYYWKVDEAGNQLPYLNELHYKLSTWA
                     DRDVQAIAGSGDFSNLEQPENFVESLKRAANESAPARLAFGPRVIGYNMHMNFSGNGW
                     GDPDERAKEVRELNRSLDFRKAVTMAVDRKKLGEALVKGPFTAIYPGGLSSGTSFYDR
                     NSTMYYPHDLEGAKALLEKVGLKDTDGNGFVNFPADKLGGRDVEIVLLVNSDYSTDRN
                     LAEGIVGQMEKLGLRIVLNALDGKQRDAANYAGRFDWMIHRNTAEFASVVQNTPQLAP
                     TGPRTSWHHRAPEGGEVDALPHETELVDIVNKFIASNDNDERAELMKQYQKVATTNVD
                     TVGLTEYPGALIINKRFSNIPPGAPIFMFNWAEDTIIRERVFVAADKQGDFELYPEQL
                     PGKPGESGPIN"
     sig_peptide     610706..610783
                     /locus_tag="Smed_4140"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.998 at
                     residue 26"
     misc_feature    610955..612637
                     /locus_tag="Smed_4140"
                     /note="The substrate-binding component of an
                     uncharacterized ABC-type
                     nickel/dipeptide/oligopeptide-like import system contains
                     the type 2 periplasmic binding fold; Region:
                     PBP2_NikA_DppA_OppA_like_4; cd08500"
                     /db_xref="CDD:173865"
     misc_feature    611162..612373
                     /locus_tag="Smed_4140"
                     /note="Bacterial extracellular solute-binding proteins,
                     family 5 Middle; Region: SBP_bac_5; pfam00496"
                     /db_xref="CDD:215949"
     gene            612904..613917
                     /locus_tag="Smed_4141"
                     /db_xref="GeneID:5319137"
     CDS             612904..613917
                     /locus_tag="Smed_4141"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21646 putative ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001312879.1"
                     /db_xref="GI:150376283"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319137"
                     /translation="MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDYSDYIRSQLIN
                     QGGASFEEADAQAQAYRKEHGLDRPLPIQYVDWITGIVTRGDFGHSLYYNKPVADVVG
                     ERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTISFLGMTVPRFLMALI
                     IVYILVFHFNVSEINSFHSARYGGAPWSWEKFVDLVKHVWPVVAIATFGGLAYNMRVM
                     RGNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETA
                     IIFALPTVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNIIADMMLAALDPRVRMGGG
                     AYA"
     misc_feature    612904..613902
                     /locus_tag="Smed_4141"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppB; COG0601"
                     /db_xref="CDD:223674"
     sig_peptide     612904..612981
                     /locus_tag="Smed_4141"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.815) with cleavage site probability 0.623 at
                     residue 26"
     misc_feature    613216..613854
                     /locus_tag="Smed_4141"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(613264..613269,613276..613281,613294..613296,
                     613327..613338,613342..613371,613378..613383,
                     613387..613389,613525..613530,613534..613536,
                     613540..613542,613549..613554,613558..613560,
                     613573..613578,613585..613587,613636..613638,
                     613678..613683,613690..613692,613711..613722,
                     613729..613734,613771..613776,613804..613809,
                     613816..613821,613825..613830,613837..613842,
                     613849..613854)
                     /locus_tag="Smed_4141"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(613345..613389,613711..613728)
                     /locus_tag="Smed_4141"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(613387..613389,613510..613512,613729..613731,
                     613765..613767,613774..613776,613804..613806)
                     /locus_tag="Smed_4141"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(613588..613626,613642..613647,613657..613659)
                     /locus_tag="Smed_4141"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            613914..615041
                     /locus_tag="Smed_4142"
                     /db_xref="GeneID:5319138"
     CDS             613914..615041
                     /locus_tag="Smed_4142"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21645 putative ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312880.1"
                     /db_xref="GI:150376284"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319138"
                     /translation="MTIEVGSTLPLAVEPEEKHHHESYSALVWRRLKRSWTGLLGLIL
                     VCLLILMAVFADFLSPVDPKVTDVAFAQPQTISFRDKDGNFVFPPRSYPVRETEELDP
                     ITFQPIIGPDYENPQVLGFFVKGAPYRLFGLIPAERHLFGAVDGTPVHLLGTDKFGRD
                     VLSRILYGSRISLMIALTVVFIVTVVGTTVGMVSGYFGGRFDAWVQRFVELVLAFPQL
                     PLYLALASLIPVTAPTNVFLAFVIIVMSALGWAQMSREVRGKTLALARIEYVRAAIAI
                     GATDRRIIFQHIFPNVMSHVIVAVTLAIPQVVLLESFLGFLGFAVKPPLISWGLMLQD
                     TANYSAIGSYPWILSPVAFVLVTVFAFNALGDGLRDAIDPY"
     misc_feature    <614349..615035
                     /locus_tag="Smed_4142"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppC; COG1173"
                     /db_xref="CDD:224094"
     misc_feature    614421..614936
                     /locus_tag="Smed_4142"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(614466..614471,614478..614483,614496..614498,
                     614526..614537,614541..614570,614577..614582,
                     614586..614588,614655..614660,614664..614666,
                     614670..614672,614679..614684,614688..614690,
                     614700..614705,614712..614714,614763..614765,
                     614805..614810,614817..614819,614838..614849,
                     614856..614861,614901..614906,614934..614936)
                     /locus_tag="Smed_4142"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(614544..614588,614838..614855)
                     /locus_tag="Smed_4142"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(614586..614588,614640..614642,614856..614858,
                     614895..614897,614904..614906,614934..614936)
                     /locus_tag="Smed_4142"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(614715..614753,614769..614774,614784..614786)
                     /locus_tag="Smed_4142"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            615053..616723
                     /locus_tag="Smed_4143"
                     /db_xref="GeneID:5319139"
     CDS             615053..616723
                     /locus_tag="Smed_4143"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21644 putative ABC transporter ATP-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312881.1"
                     /db_xref="GI:150376285"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319139"
                     /translation="MATIESIVPAPEERRDRHTKEARPVIDARRVAVSFKVENGAVEA
                     VKDVSFQLYRGETVAIVGESGSGKSVTARTVMGLLSKRATIAPQARIEYDGKDVLKFS
                     KRERRALRGDRISMIFQEPMSSLNPVYTIGSQIVEAIRAHRRVGRRAAAERALELLRH
                     VQIPDPEARLNQYPHQLSGGQRQRVMIAMALANDPDVLIADEPTTALDVTVQAQILNL
                     IRKLQQELGMAVILITHDLTVVRQFSDYVYVMQLGEVKEHNTTEALFVDPQHAYTRRL
                     LASEPSGSANPLPADAPIMLDGRNVRVSFTLKKGGFFRPEYKELIAVDGLSLNLRRHE
                     TLGLVGESGSGKTTFGQALIRLINTDGGEVYFEGEPIHDKNRKAMRPLRSKIQIVFQD
                     PFSSLNPRMSVGQIIEEGLIVNGIGESRKDRLKRVEDALVSAGMPANILSRFPHEFSG
                     GQRQRIAIARAIALEPEFILLDEPTSALDLSVQAQIIELLRRLQDERGLSYLFISHDL
                     KVVRALCHRVAVMQNGKIVEEGPVSEILNRPKTAYTERLVKAAFEVAA"
     misc_feature    615119..616717
                     /locus_tag="Smed_4143"
                     /note="ABC-type uncharacterized transport system,
                     duplicated ATPase component [General function prediction
                     only]; Region: COG4172"
                     /db_xref="CDD:226641"
     misc_feature    615125..615829
                     /locus_tag="Smed_4143"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    615236..615259
                     /locus_tag="Smed_4143"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    order(615245..615250,615254..615262,615407..615409,
                     615653..615658,615755..615757)
                     /locus_tag="Smed_4143"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    615398..615409
                     /locus_tag="Smed_4143"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    615581..615610
                     /locus_tag="Smed_4143"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    615641..615658
                     /locus_tag="Smed_4143"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    615665..615676
                     /locus_tag="Smed_4143"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    615743..615763
                     /locus_tag="Smed_4143"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    615830..>615934
                     /locus_tag="Smed_4143"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     misc_feature    615935..616642
                     /locus_tag="Smed_4143"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    616070..616093
                     /locus_tag="Smed_4143"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    order(616079..616084,616088..616096,616223..616225,
                     616466..616471,616568..616570)
                     /locus_tag="Smed_4143"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    616214..616225
                     /locus_tag="Smed_4143"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    616394..616423
                     /locus_tag="Smed_4143"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    616454..616471
                     /locus_tag="Smed_4143"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    616478..616489
                     /locus_tag="Smed_4143"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    616556..616576
                     /locus_tag="Smed_4143"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    616631..>616714
                     /locus_tag="Smed_4143"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     gene            616757..618130
                     /locus_tag="Smed_4144"
                     /db_xref="GeneID:5319140"
     CDS             616757..618130
                     /locus_tag="Smed_4144"
                     /note="PFAM: glycoside hydrolase family 4;
                     KEGG: sme:SMb21643 probable alpha-galactosidase
                     (melibiase) protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="YP_001312882.1"
                     /db_xref="GI:150376286"
                     /db_xref="InterPro:IPR001088"
                     /db_xref="GeneID:5319140"
                     /translation="MTRQPRITFIGAGSTVFMKNIIGDILQRPALSAATIALMDVNPE
                     RLAESEIVAGKLARTLGAGARIETHSDQRKALTGADFVVVAFQIGGYEPCTVTDFEVP
                     KKYGLRQTIADTLGVGGIMRGLRTVPHLWKICEDMLEVCPEAILLQYVNPMAINTWAI
                     AERYPAIKQVGLCHSVQGTAYELARDLEIPLEEIRYRAAGINHMAFYLKFEHRQKDGS
                     YRDLYPDLIRGYREGRFPKPSHWNPRCPNKVRYEMLTRLGYFVTESSEHFAEYTPYFI
                     KEGRPDLIEKFGIPLDEYPKRCIEQIERWKGQAAAFKEAETMEVAESREYASSIMNSV
                     WTGEPSVIYGNLRNNGCITSLPENCAAEMPCLVDQSGIQPTHIGALPPQLTALIRTNI
                     NVQELTVQALVTENREHLYHAAMMDPHTAAELDLDQIWSLVDDLLTAHRDWIPEWARV
                     AQKVAAA"
     misc_feature    616769..618100
                     /locus_tag="Smed_4144"
                     /note="alpha-galactosidase; Provisional; Region: PRK15076"
                     /db_xref="CDD:185035"
     misc_feature    616769..618067
                     /locus_tag="Smed_4144"
                     /note="Glycoside Hydrolases Family 4; Alpha-glucosidases
                     and alpha-galactosidases; Region:
                     GH4_alpha_glucosidase_galactosidase; cd05297"
                     /db_xref="CDD:133433"
     misc_feature    order(616793..616798,616874..616879,616889..616891,
                     617009..617017,617024..617029,617102..617104,
                     617141..617143,617201..617203,617207..617209,
                     617270..617272)
                     /locus_tag="Smed_4144"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:133433"
     misc_feature    order(617102..617104,617207..617209,617273..617275,
                     617363..617365,617546..617548,617555..617557)
                     /locus_tag="Smed_4144"
                     /note="sugar binding site [chemical binding]; other site"
                     /db_xref="CDD:133433"
     misc_feature    order(617273..617275,617363..617365)
                     /locus_tag="Smed_4144"
                     /note="divalent metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:133433"
     misc_feature    order(617330..617332,617339..617341,617387..617389,
                     617411..617413,617765..617767,617801..617803,
                     617858..617863,617867..617869,617873..617884)
                     /locus_tag="Smed_4144"
                     /note="putative tetramer (dimer of dimers) interface
                     [polypeptide binding]; other site"
                     /db_xref="CDD:133433"
     misc_feature    order(617525..617527,617561..617563,617897..617902,
                     617912..617914,617921..617923,617933..617935,
                     617942..617944,617954..617956,617972..617974,
                     617978..617980,617987..617992,617999..618004,
                     618017..618019,618023..618025,618029..618031,
                     618035..618037)
                     /locus_tag="Smed_4144"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:133433"
     gene            618508..618852
                     /locus_tag="Smed_4145"
                     /db_xref="GeneID:5319141"
     CDS             618508..618852
                     /locus_tag="Smed_4145"
                     /note="PFAM: protein of unknown function DUF992;
                     KEGG: sme:SMb21642 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312883.1"
                     /db_xref="GI:150376287"
                     /db_xref="InterPro:IPR009333"
                     /db_xref="GeneID:5319141"
                     /translation="MAEEAKEQAQAGFVKRGTLSCDIAAGIGLVVGSSKALTCVFEAD
                     GQKSPHRYSGTIDKLGLDIGVTAESRVVWQVYPKPKTKLKGALAGTYSGLSAEFAAGL
                     GLGAKSLVGSKK"
     misc_feature    618508..>618840
                     /locus_tag="Smed_4145"
                     /note="Protein of unknown function (DUF992); Region:
                     DUF992; pfam06186"
                     /db_xref="CDD:218930"
     gene            619137..620054
                     /locus_tag="Smed_4146"
                     /db_xref="GeneID:5319142"
     CDS             619137..620054
                     /locus_tag="Smed_4146"
                     /note="TIGRFAM: phenylacetic acid degradation operon
                     negative regulatory protein PaaX;
                     PFAM: PaaX domain protein; PaaX domain protein domain;
                     KEGG: sme:SMb21641 putative regulator of phenylacetic acid
                     degradation, ArsR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaX family transcriptional regulator"
                     /protein_id="YP_001312884.1"
                     /db_xref="GI:150376288"
                     /db_xref="InterPro:IPR011965"
                     /db_xref="InterPro:IPR012906"
                     /db_xref="InterPro:IPR013225"
                     /db_xref="GeneID:5319142"
                     /translation="MQGQGDNSAKAGSKAIREILDEVPLRAASFIVTIYGDVVEPRGG
                     AIWIGNLIEICAGVGISETLVRTAVSRLVAAGRLAGEREGRRSFYRLTDAARTEFAGA
                     ARVIFGPPEEASWHFVQLMGSSAEDRMLMLERSGYARLSPRLAIGVRPFPTAIMPALV
                     FRAEIAEGAEELKAFASASWDLAPHAEAYRRFLGSFQSLAAPADAGSMTPADCLTARL
                     LLVHQFRFVALRDPRLPAETLPEGWPGDEARRLFARLYLNLSHPADLHAAQHFVAASG
                     PLAASTGATEERFRMLRREGVPASGCKSV"
     misc_feature    619212..619421
                     /locus_tag="Smed_4146"
                     /note="PaaX-like protein; Region: PaaX; pfam07848"
                     /db_xref="CDD:191871"
     misc_feature    619221..620009
                     /locus_tag="Smed_4146"
                     /note="phenylacetic acid degradation operon negative
                     regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277"
                     /db_xref="CDD:233808"
     misc_feature    619461..619922
                     /locus_tag="Smed_4146"
                     /note="PaaX-like protein C-terminal domain; Region:
                     PaaX_C; pfam08223"
                     /db_xref="CDD:219751"
     gene            620238..621239
                     /gene="paaA"
                     /locus_tag="Smed_4147"
                     /db_xref="GeneID:5319143"
     CDS             620238..621239
                     /gene="paaA"
                     /locus_tag="Smed_4147"
                     /note="with PaaBCDE catalyzes the hydroxylation of
                     phenylacetyl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase subunit PaaA"
                     /protein_id="YP_001312885.1"
                     /db_xref="GI:150376289"
                     /db_xref="InterPro:IPR007814"
                     /db_xref="InterPro:IPR011881"
                     /db_xref="GeneID:5319143"
                     /translation="MYAQMVKTDAPRIKSRSEMDPRERAFQERIDAGQKIEPKEWMPE
                     GYRRTLIRQISQHAHSEIVGQLPEGNWITRAPTLERKAILLAKVQDEAGHGLYLYCAA
                     ETLGVSRDALYDQLHSGKAKYSSIFNYPTLTWADIGAIGWLVDGAAIMNQVPLQRCSY
                     GPYARAMVRICKEESFHQRQGYDILMKMVKGTTAQKAMVQDALDRWWWPSLMMFGPSD
                     DASVHSAQSMAWKIKQNSNDELRQKFVDQTVPQAEYLGLTVPDPDLTWNEEKGGYDFG
                     EPDWNEFFEVIAGNGPCNGERLGARRQAWDDGAWFRDGLTAHAEKATARRAHSVGAE"
     misc_feature    620259..621200
                     /gene="paaA"
                     /locus_tag="Smed_4147"
                     /note="phenylacetate-CoA oxygenase subunit PaaA;
                     Provisional; Region: paaA; PRK13778"
                     /db_xref="CDD:184320"
     misc_feature    620313..621176
                     /gene="paaA"
                     /locus_tag="Smed_4147"
                     /note="phenylacetate-CoA oxygenase, PaaG subunit; Region:
                     PA_CoA_Oxy1; TIGR02156"
                     /db_xref="CDD:131211"
     gene            621257..621541
                     /gene="paaB"
                     /locus_tag="Smed_4148"
                     /db_xref="GeneID:5319144"
     CDS             621257..621541
                     /gene="paaB"
                     /locus_tag="Smed_4148"
                     /note="with PaaBCDE catalyzes the hydroxylation of
                     phenylacetyl-CoA; involved in phenylacetate degradation"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase subunit PaaB"
                     /protein_id="YP_001312886.1"
                     /db_xref="GI:150376290"
                     /db_xref="InterPro:IPR009359"
                     /db_xref="GeneID:5319144"
                     /translation="MSSEWPLWEVFIRGQHGLNHRHVGSLHAPDAEMAINNARDVYVR
                     RNEGVSIWVVRSIDIVASAPSEKGPLFEPSNAKVYRHPTFFDIPDEVGHM"
     misc_feature    621257..621538
                     /gene="paaB"
                     /locus_tag="Smed_4148"
                     /note="phenylacetate-CoA oxygenase subunit PaaB;
                     Provisional; Region: paaB; PRK13781"
                     /db_xref="CDD:237504"
     gene            621541..622326
                     /locus_tag="Smed_4149"
                     /db_xref="GeneID:5319145"
     CDS             621541..622326
                     /locus_tag="Smed_4149"
                     /note="TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit;
                     PFAM: phenylacetic acid catabolic family protein;
                     KEGG: sme:SMb21638 putative phenylacetic acid degradation
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase subunit PaaI"
                     /protein_id="YP_001312887.1"
                     /db_xref="GI:150376291"
                     /db_xref="InterPro:IPR007814"
                     /db_xref="InterPro:IPR011882"
                     /db_xref="GeneID:5319145"
                     /translation="MAQTIAIEAAVERSALFEFLLGMGDNTLVLGHRLSEWCGHSPAL
                     EEDIALANTALDLIGQTQLWLGLAGEVEGKGRNADDLAFLRDVREFRNLLLAERPNGD
                     YGRTLMRQFLFDAWHYLALKGLRASSDPRIAAIAEKTSKEVAYHLERSRDLVIRLGDG
                     TAESHARMKKALDELWSYTGEMFVNEAHDAALAAAGLAPEPESLEAEWNTLVAETLCA
                     ATLGKPQGGYMHRGGKRGLHTEHLGYVLAEMQFLQRAYPGASW"
     misc_feature    621583..622323
                     /locus_tag="Smed_4149"
                     /note="Phenylacetic acid catabolic protein; Region:
                     PaaA_PaaC; pfam05138"
                     /db_xref="CDD:218460"
     gene            622336..622860
                     /locus_tag="Smed_4150"
                     /db_xref="GeneID:5319199"
     CDS             622336..622860
                     /locus_tag="Smed_4150"
                     /note="TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit;
                     PFAM: protein of unknown function DUF59;
                     KEGG: sme:SMb21637 putative phenylacetic acid degradation
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase subunit PaaJ"
                     /protein_id="YP_001312888.1"
                     /db_xref="GI:150376292"
                     /db_xref="InterPro:IPR002744"
                     /db_xref="InterPro:IPR011883"
                     /db_xref="GeneID:5319199"
                     /translation="MATALRPSIEDVWNWLSHVPDPEIPVISVTDLGIIRDVAWDREA
                     LVVTVTPTYSGCPATAVINQDIERALKEKGIENVRLERRLSPAWTTDWISAEGREKLG
                     NYGIAAPIDGTTAEGRLMERIAGLAGGAPLTVQCPRCNSGRTEKISQFGSTPCKASYR
                     CRDCLEPFDYFKCI"
     misc_feature    622336..622641
                     /locus_tag="Smed_4150"
                     /note="Predicted metal-sulfur cluster biosynthetic enzyme
                     [General function prediction only]; Region: PaaD; COG2151"
                     /db_xref="CDD:225062"
     misc_feature    622390..622857
                     /locus_tag="Smed_4150"
                     /note="phenylacetate-CoA oxygenase, PaaJ subunit; Region:
                     PA_CoA_Oxy4; TIGR02159"
                     /db_xref="CDD:131214"
     gene            622883..623959
                     /locus_tag="Smed_4151"
                     /db_xref="GeneID:5319200"
     CDS             622883..623959
                     /locus_tag="Smed_4151"
                     /note="TIGRFAM: phenylacetate-CoA oxygenase/reductase,
                     PaaK subunit;
                     PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain
                     protein; Oxidoreductase FAD-binding domain protein;
                     KEGG: sme:SMb21636 putative ferredoxin reductase electron
                     transfer component protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase/reductase subunit
                     PaaK"
                     /protein_id="YP_001312889.1"
                     /db_xref="GI:150376293"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR001221"
                     /db_xref="InterPro:IPR001433"
                     /db_xref="InterPro:IPR001709"
                     /db_xref="InterPro:IPR001834"
                     /db_xref="InterPro:IPR006058"
                     /db_xref="InterPro:IPR008333"
                     /db_xref="InterPro:IPR011884"
                     /db_xref="GeneID:5319200"
                     /translation="MARFHPLQVTEVRRETRDAVVVTLEPRDEDRAAFDFTQGQYLTF
                     RRIFDGEELRRSYSICSGLGEGALRVGIKRVDGGCFSNWANEVLKPGDTLEAMPPMGT
                     FFVPVEPEVSRHYLGFAGGSGITPVLSLVKTVLAREPRSAFTLVYANRHFSSIMFREE
                     LDDLKNLYLGRLSVLHILESEAQDIDLFSGRLDLEKCTALFRHWIDVKSADIAFICGP
                     EPMMQAVAATLRAHGVSDSRIRFELFGSSQPGRARRRTASPAGTDGGSRCEATVTLDG
                     ATRSFTLPKRGQSLLEAALENRMDAPYACKAGVCSSCRAKVLEGEVEMESNNALEDYE
                     VEQGYVLMCQSYPLSDRVVVSYDE"
     misc_feature    622892..623953
                     /locus_tag="Smed_4151"
                     /note="phenylacetate-CoA oxygenase/reductase, PaaK
                     subunit; Region: PA_CoA_Oxy5; TIGR02160"
                     /db_xref="CDD:131215"
     misc_feature    622892..623617
                     /locus_tag="Smed_4151"
                     /note="NAD(P) binding domain of ferredoxin reductase like
                     phenylacetic acid (PA) degradation oxidoreductase. PA
                     oxidoreductases of E. coli hydroxylate PA-CoA in the
                     second step of PA degradation. Members of this group
                     typically fuse a ferredoxin reductase-like...; Region:
                     PA_degradation_oxidoreductase_like; cd06214"
                     /db_xref="CDD:99810"
     misc_feature    order(623003..623005,623045..623056,623093..623101,
                     623105..623107,623117..623125,623246..623248,
                     623255..623257,623606..623608,623612..623614)
                     /locus_tag="Smed_4151"
                     /note="FAD binding pocket [chemical binding]; other site"
                     /db_xref="CDD:99810"
     misc_feature    order(623045..623047,623051..623056)
                     /locus_tag="Smed_4151"
                     /note="FAD binding motif [chemical binding]; other site"
                     /db_xref="CDD:99810"
     misc_feature    order(623114..623116,623123..623125,623132..623134,
                     623153..623155,623177..623179,623183..623185)
                     /locus_tag="Smed_4151"
                     /note="phosphate binding motif [ion binding]; other site"
                     /db_xref="CDD:99810"
     misc_feature    order(623231..623233,623243..623254,623258..623260)
                     /locus_tag="Smed_4151"
                     /note="beta-alpha-beta structure motif; other site"
                     /db_xref="CDD:99810"
     misc_feature    623243..623260
                     /locus_tag="Smed_4151"
                     /note="NAD(p) ribose binding residues [chemical binding];
                     other site"
                     /db_xref="CDD:99810"
     misc_feature    order(623246..623251,623324..623332,623531..623536)
                     /locus_tag="Smed_4151"
                     /note="NAD binding pocket [chemical binding]; other site"
                     /db_xref="CDD:99810"
     misc_feature    623528..623545
                     /locus_tag="Smed_4151"
                     /note="NAD(P)-pyrophosphate-nicotinamide binding residues
                     [chemical binding]; other site"
                     /db_xref="CDD:99810"
     misc_feature    623693..623941
                     /locus_tag="Smed_4151"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    order(623783..623788,623795..623797,623804..623806,
                     623810..623821,623906..623911)
                     /locus_tag="Smed_4151"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    order(623795..623797,623810..623812,623819..623821,
                     623909..623911)
                     /locus_tag="Smed_4151"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     gene            623999..626059
                     /locus_tag="Smed_4152"
                     /db_xref="GeneID:5319201"
     CDS             623999..626059
                     /locus_tag="Smed_4152"
                     /note="catalyzes the ring cleavage reaction in
                     phenylacetate degradation and the formation of
                     3-hydroxyacyl-CoA from crotonyl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aldehyde dehydrogenase/enoyl-CoA
                     hydratase"
                     /protein_id="YP_001312890.1"
                     /db_xref="GI:150376294"
                     /db_xref="InterPro:IPR002086"
                     /db_xref="InterPro:IPR002539"
                     /db_xref="InterPro:IPR011966"
                     /db_xref="GeneID:5319201"
                     /translation="MVTDRPRRLESYVAGVWVRGDKDGVTLCDAATGAPVALVDSTGI
                     DFAAALAYGREKGGPALRRMSLHERAMMLKMLAQALMERKEEFYALSTATGATRPDSW
                     IDIEGGIGTLFSYASKARRELPNSRVLLDGDVEPLSRDGTFSAQHMLTPLQGIAVHIN
                     AFNFPCWGMLEKLAPTLIAGMPAIIKPASQTAYLAELLVRRIIETGLLPQGALQLVCG
                     SAGDLLDHAGDQDVVTFTGSSATGRMLKAHPAILKNSVRFTMEADSLNAAVLGLDAAP
                     GTEEFDLFAREVFREMTSKAGQKCTAIRRVIVPRAHCDALVAALGERFARLPLGAPAD
                     ENVRMGPLASLGQREEVRARIRDLAAEAEIVAGDPTRPQLVSGDAEAGAFLSPVLLYC
                     DRPSAARAVHDIEAFGPVSTVMPYETTDDAIELVRRGKGSLVTSVFTNDPDTAQELVI
                     GMAPFHGRVLIGNRLSAKSSTGHGSPLPGLVHGGPGRAGGGEELGGMRGVKHYMQRTA
                     VQGPPGLISAVMGRWIKGAPGRHESEHPFRKSLAELRTGDQLVTGTRVVTLEDIEHFA
                     DFTGDTFYAHMDEEAARANPFFDGRVAHGYLVVSLAAGLFVDPAPGPVLANYGVDGLR
                     FLAPVYPGDALQVRLTCKEISPRMNTEYGEVRWDCCVTNQTGATVAQYDVLTMVAKAR
                     GEEK"
     misc_feature    624011..626038
                     /locus_tag="Smed_4152"
                     /note="bifunctional aldehyde dehydrogenase/enoyl-CoA
                     hydratase; Provisional; Region: PRK11563"
                     /db_xref="CDD:236931"
     misc_feature    624023..625561
                     /locus_tag="Smed_4152"
                     /note="N-terminal domain of the monoamine oxidase C
                     dehydratase; Region: ALDH_MaoC-N; cd07128"
                     /db_xref="CDD:143446"
     misc_feature    order(624326..624328,624488..624490,624899..624901,
                     625418..625420,625424..625429)
                     /locus_tag="Smed_4152"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:143446"
     misc_feature    order(624389..624391,624401..624403,624416..624418,
                     624422..624427,624431..624433,624437..624439,
                     624725..624727,624734..624736,625277..625279,
                     625322..625324,625364..625381,625400..625405,
                     625409..625411,625436..625441,625469..625474,
                     625490..625492,625511..625528,625532..625534,
                     625541..625543,625550..625552)
                     /locus_tag="Smed_4152"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143446"
     misc_feature    order(624473..624478,624482..624484,624554..624556,
                     624560..624565,624701..624712,624719..624721)
                     /locus_tag="Smed_4152"
                     /note="NADP binding site [chemical binding]; other site"
                     /db_xref="CDD:143446"
     misc_feature    order(624485..624487,624779..624781,624887..624889,
                     624896..624898)
                     /locus_tag="Smed_4152"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143446"
     misc_feature    625616..626044
                     /locus_tag="Smed_4152"
                     /note="MaoC_C  The C-terminal hot dog fold of the MaoC
                     (monoamine oxidase C) dehydratase regulatory protein.
                     Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN
                     [Pseudomonas putida], which are putative ring-opening
                     enzymes involved in phenylacetic acid...; Region: MaoC_C;
                     cd03452"
                     /db_xref="CDD:239536"
     misc_feature    order(625904..625906,625913..625915,625970..625972,
                     625976..625978)
                     /locus_tag="Smed_4152"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239536"
     gene            626056..626559
                     /locus_tag="Smed_4153"
                     /db_xref="GeneID:5319202"
     CDS             626056..626559
                     /locus_tag="Smed_4153"
                     /note="PFAM: thioesterase superfamily protein;
                     KEGG: sme:SMb21634 putative acyl-CoA thioester hydrolase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase superfamily protein"
                     /protein_id="YP_001312891.1"
                     /db_xref="GI:150376295"
                     /db_xref="InterPro:IPR006683"
                     /db_xref="GeneID:5319202"
                     /translation="MMTDQETRHLVMTVLMTPDMANFSGKVHGGALLNLLDRVAFSCA
                     SRFSKQYAVTLSVDQVIFKEPILVGELVTFRAAVNFAGRTSMEVGIRVEAENIRAGTR
                     RHTNSCYFTMVAVDEAGRPVAVPEYRPETATEKRRHQAAELRRTLRREFAHRLKTVAE
                     TGRDVVD"
     misc_feature    626071..626430
                     /locus_tag="Smed_4153"
                     /note="Brown fat-inducible thioesterase (BFIT).  Brain
                     acyl-CoA hydrolase (BACH).  These enzymes deacylate
                     long-chain fatty acids by hydrolyzing acyl-CoA thioesters
                     to free fatty acids and CoA-SH. Eukaryotic members of this
                     family are expressed in brain, testis; Region: BFIT_BACH;
                     cd03442"
                     /db_xref="CDD:239526"
     gene            complement(626618..627409)
                     /locus_tag="Smed_4154"
                     /db_xref="GeneID:5319203"
     CDS             complement(626618..627409)
                     /locus_tag="Smed_4154"
                     /EC_number="4.2.1.17"
                     /note="Catalyzes the reversible hydration of unsaturated
                     fatty acyl-CoA to beta-hydroxyacyl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="YP_001312892.1"
                     /db_xref="GI:150376296"
                     /db_xref="InterPro:IPR001753"
                     /db_xref="InterPro:IPR011968"
                     /db_xref="GeneID:5319203"
                     /translation="MSASDTVLSAFETGVLRLTLNRPDKLNAFNEEMHLALRAGFERA
                     HSDDDVRAVLLTGAGRGFSAGQDLGDRDPHGGGTPNLGHTIETFYNPLLRLIRGLEKP
                     VVCAVNGVAAGAGANIAFACDITLAARSARFIQAFAKIGLIPDSGGTWNLPRLVGEAR
                     AKALTLTAEPLDAETAASWGLIWRAVDDAALMDEAFALAARLAAGPTRGFGLTKRAIQ
                     AAATHSFDEQLDLERDLQREAGRSADYAEGVTAFLDKRKPEFKGR"
     misc_feature    complement(626621..627403)
                     /locus_tag="Smed_4154"
                     /note="enoyl-CoA hydratase; Provisional; Region: PRK08140"
                     /db_xref="CDD:236163"
     misc_feature    complement(626852..627370)
                     /locus_tag="Smed_4154"
                     /note="Crotonase/Enoyl-Coenzyme A (CoA) hydratase
                     superfamily. This superfamily contains a diverse set of
                     enzymes including enoyl-CoA hydratase, napthoate synthase,
                     methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA
                     dehydratase, and dienoyl-CoA isomerase; Region:
                     crotonase-like; cd06558"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(626990..626992,626999..627004,
                     627068..627076,627080..627082,627206..627220,
                     627230..627232,627326..627328,627332..627334))
                     /locus_tag="Smed_4154"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(627068..627070,627212..627214))
                     /locus_tag="Smed_4154"
                     /note="oxyanion hole (OAH) forming residues; other site"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(626861..626863,626870..626872,
                     626903..626905,626912..626917,626921..626926,
                     626930..626935,626948..626953,626957..626965,
                     626969..626971,626987..626998,627032..627043,
                     627104..627106,627128..627130))
                     /locus_tag="Smed_4154"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119339"
     misc_feature    complement(626627..>626776)
                     /locus_tag="Smed_4154"
                     /note="2-enoyl-CoA Hydratase C-terminal region; Region:
                     ECH_C; pfam13766"
                     /db_xref="CDD:205939"
     gene            627501..628829
                     /locus_tag="Smed_4155"
                     /db_xref="GeneID:5319204"
     CDS             627501..628829
                     /locus_tag="Smed_4155"
                     /EC_number="5.1.2.3"
                     /note="PFAM: 3-hydroxyacyl-CoA dehydrogenase domain
                     protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding;
                     KEGG: sme:SMb21632 putative 3-hydroxyacyl-CoA
                     dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA epimerase"
                     /protein_id="YP_001312893.1"
                     /db_xref="GI:150376297"
                     /db_xref="InterPro:IPR006108"
                     /db_xref="InterPro:IPR006176"
                     /db_xref="GeneID:5319204"
                     /translation="MALNIVHRGGVALATTGNPLRHVFRAERVARHAPELAGVEPRPI
                     RSAAVIGGGTMGTGIAAALCNAGLPLVIVERDEAAREGAVARLRAIFDGAVKRRRISA
                     GLAAERLARVTGATDYAVLAEADLIIEAVFEDLDVKRDVFRKVAAACRHDAVLATNTS
                     YLNPERIADGIASPERFLGLHFFSPAQVMKLLEIVPTGATAPEALATGFALARMLNKI
                     PVRAGISDGFIGNRILKVMRGQAERLLVTGASPSAVDAAMRAFGLPMGPFEAQDLGGL
                     DIAAFQRRAARARGLPVFAPVSDRLCAIARFGQKSGGGWYDYVPGHRTPLPSEAVARL
                     VEEEAQGWPRLDWDEASIIDCILWPMVNEAARIVEDGTALRPSDIDLVEIHGYGFPRW
                     RGGLMHHAQAQGLDRIVAALGAFAEKGLADPPSTLLVRAAAQGRFSEALR"
     misc_feature    627687..628169
                     /locus_tag="Smed_4155"
                     /note="3-hydroxyacyl-CoA dehydrogenase, NAD binding
                     domain; Region: 3HCDH_N; pfam02737"
                     /db_xref="CDD:202367"
     misc_feature    627696..628454
                     /locus_tag="Smed_4155"
                     /note="3-hydroxybutyryl-CoA dehydrogenase; Validated;
                     Region: PRK05808"
                     /db_xref="CDD:180269"
     misc_feature    628179..628454
                     /locus_tag="Smed_4155"
                     /note="3-hydroxyacyl-CoA dehydrogenase, C-terminal domain;
                     Region: 3HCDH; pfam00725"
                     /db_xref="CDD:216084"
     misc_feature    628566..628820
                     /locus_tag="Smed_4155"
                     /note="3-hydroxyacyl-CoA dehydrogenase, C-terminal domain;
                     Region: 3HCDH; pfam00725"
                     /db_xref="CDD:216084"
     gene            628974..630071
                     /locus_tag="Smed_4156"
                     /db_xref="GeneID:5319205"
     CDS             628974..630071
                     /locus_tag="Smed_4156"
                     /note="TIGRFAM: carboxynorspermidine decarboxylase;
                     PFAM: Orn/DAP/Arg decarboxylase 2;
                     KEGG: sme:SMb21631 putative carboxynorspermidine
                     decarboxylase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="YP_001312894.1"
                     /db_xref="GI:150376298"
                     /db_xref="InterPro:IPR000183"
                     /db_xref="InterPro:IPR005730"
                     /db_xref="GeneID:5319205"
                     /translation="MIETPYYLIDKSKLIRNMEKIAHVREKSGAKALLALKCFATWSV
                     FDLMRDYMDGTTSSSLFEVRLGREKFGKETHAYSVAYGDNEIDEVVLHADKIIFNSIS
                     QLERYAERAAGIARGLRLNPQVSSSSFDLADPARPFSRLGEWDVAKVERVMDRINGFM
                     IHNNCENKNFDLFDCLLAQIEERFGSLLERADWVSLGGGIHFTGDDYPVDTFSARLRA
                     FSDRYDVQVYLEPGEASITKSTTLEVTVLDTLYNGKNLAIVDSSIEAHMLDLLIYRET
                     AKVSPNEGPHSYMICGKSCLAGDVFGEFRFADALKVGDRISFQDAAGYTMVKKNWFNG
                     VKMPAIAIKELDGSVRTVREFTYADFEKSLS"
     misc_feature    628977..630065
                     /locus_tag="Smed_4156"
                     /note="carboxynorspermidine decarboxylase; Region: nspC;
                     TIGR01047"
                     /db_xref="CDD:233247"
     misc_feature    628983..630005
                     /locus_tag="Smed_4156"
                     /note="Type III Pyridoxal 5-phosphate (PLP)-Dependent
                     Enzyme Carboxynorspermidine Decarboxylase; Region:
                     PLPDE_III_CANSDC; cd06829"
                     /db_xref="CDD:143502"
     misc_feature    order(628983..628985,629082..629084,629145..629150,
                     629154..629159,629220..629222,629268..629270,
                     629277..629279,629289..629291,629370..629381,
                     629712..629723,629739..629741,629745..629747,
                     629751..629753,629760..629762,629847..629849,
                     629853..629861,629868..629870,629952..629960,
                     629967..629975)
                     /locus_tag="Smed_4156"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143502"
     misc_feature    order(629076..629078,629082..629084,629139..629141,
                     629205..629207,629328..629330,629457..629459,
                     629466..629468,629565..629570,629661..629672,
                     629856..629861,629943..629945,629955..629957,
                     629967..629969)
                     /locus_tag="Smed_4156"
                     /note="active site"
                     /db_xref="CDD:143502"
     misc_feature    order(629076..629078,629082..629084,629139..629141,
                     629205..629207,629328..629330,629457..629459,
                     629466..629468,629565..629570,629661..629672,
                     629856..629858,629943..629945)
                     /locus_tag="Smed_4156"
                     /note="pyridoxal 5'-phosphate (PLP) binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:143502"
     misc_feature    order(629082..629084,629856..629858)
                     /locus_tag="Smed_4156"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143502"
     misc_feature    order(629466..629468,629670..629672,629856..629861,
                     629943..629945,629955..629957,629967..629969)
                     /locus_tag="Smed_4156"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:143502"
     gene            630112..631353
                     /locus_tag="Smed_4157"
                     /db_xref="GeneID:5319206"
     CDS             630112..631353
                     /locus_tag="Smed_4157"
                     /note="PFAM: Saccharopine dehydrogenase;
                     KEGG: sme:SMb21630 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase"
                     /protein_id="YP_001312895.1"
                     /db_xref="GI:150376299"
                     /db_xref="InterPro:IPR005097"
                     /db_xref="GeneID:5319206"
                     /translation="MKKNVLIIGAGGVAQVVAHKCAQNSDVLGDIHIASRTVEKCRAI
                     VESVREKKSLKTEVRLEAHALDALDVEATKALIASTGSKIVINVGSAFVNMSVLRACM
                     DTGVAYMDTAIHEEPNKICETPPWYGNYEWKRAAECKEKGITAILGVGFDPGVVNAYA
                     RLAKDDYFDKVTAIDIVDINAGNHGKYFATNFDPEINFREFTGVVYSWQKGAWQTNRM
                     FEIGKEFDLPVVGKRKAYMTGHDEIHSLSKNMDGADVRFWMGFGDHYINVFTVLKNLG
                     LLSEQPVKTAEGLEVVPLKVVKAVLPDPASLAPGYEGKTCIGDFVKGFKDGKEREVFI
                     YNVADHKQAFEEVGSQGISYTAGVPPVAAAMLIASGEWDVKQMANVEELPPRPFLDLL
                     SRIGLPTRIKDAEGDRPLSFS"
     sig_peptide     630112..630174
                     /locus_tag="Smed_4157"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.800) with cleavage site probability 0.556 at
                     residue 21"
     misc_feature    630115..631329
                     /locus_tag="Smed_4157"
                     /note="Saccharopine dehydrogenase and related proteins
                     [Amino acid transport and metabolism]; Region: LYS9;
                     COG1748"
                     /db_xref="CDD:224662"
     misc_feature    630115..>630312
                     /locus_tag="Smed_4157"
                     /note="NAD(P) binding domain of amino acid
                     dehydrogenase-like proteins; Region:
                     NAD_bind_amino_acid_DH; cl17226"
                     /db_xref="CDD:247780"
     misc_feature    order(630142..630150,630214..630219)
                     /locus_tag="Smed_4157"
                     /note="NAD(P) binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:133449"
     gene            631356..632606
                     /locus_tag="Smed_4158"
                     /db_xref="GeneID:5319207"
     CDS             631356..632606
                     /locus_tag="Smed_4158"
                     /EC_number="5.1.1.1"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: rle:RL4378 putative LacI family transcriptional
                     regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="YP_001312896.1"
                     /db_xref="GI:150376300"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5319207"
                     /translation="MWRPYNRPAFSAGSGEKHPLRIVAGPLRGPSLPRGGFAKICFRR
                     IIIGLLGKTFSHIDFESEKRFSHPWFSREEAKLSSQRGKGHRVTIHDLARVAGVSVST
                     VSKALNDNGRMAADTRERIKTLAAEIGFRPNALAKGLLSNRSFTVGLLTNDTYGRFTL
                     PVMAGISEALVDHGVSVFLCAIEDDPALGKIHVDAMLDKQVDGIIATGKRVDRSLPVD
                     LAGLPVPVVYAFTKGEPGSVTLTSDDRHGARLATEWLKELGRQRLVHITGPREFVSAV
                     ERAEAFRTVAGNGAPVLHGVWSEAWGHEAIDRIWKEGGERPDGIFCGNDQIARGVVDA
                     LRERGARVPGDVSVIGFDNWEIMAAQTRPPLTTIDTNLKELGREAGLMVLALAEGRAI
                     EPGLRRLPCKLVIRDSCGGGRRQN"
     misc_feature    631614..632585
                     /locus_tag="Smed_4158"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    631623..631772
                     /locus_tag="Smed_4158"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(631623..631625,631647..631661,631665..631670,
                     631677..631679,631692..631697,631704..631706,
                     631743..631745,631752..631754,631761..631766,
                     631770..631772)
                     /locus_tag="Smed_4158"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    631743..631772
                     /locus_tag="Smed_4158"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    631791..632567
                     /locus_tag="Smed_4158"
                     /note="Ligand binding domain of the LacI tanscriptional
                     regulator family belonging to the type I
                     periplasmic-binding fold protein superfamily; Region:
                     PBP1_LacI_sugar_binding_like; cd06267"
                     /db_xref="CDD:107262"
     misc_feature    order(631791..631793,631830..631838,631845..631850,
                     631854..631859,631878..631892,631896..631898,
                     631929..631931,631938..631940,631947..631955,
                     632253..632255,632340..632342,632352..632354,
                     632361..632366)
                     /locus_tag="Smed_4158"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107262"
     misc_feature    order(631827..631832,631839..631841,631974..631976,
                     632043..632045,632079..632081,632187..632189,
                     632244..632246,632409..632411,632463..632465)
                     /locus_tag="Smed_4158"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107262"
     gene            632630..633895
                     /locus_tag="Smed_4159"
                     /db_xref="GeneID:5319208"
     CDS             632630..633895
                     /locus_tag="Smed_4159"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb20634 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001312897.1"
                     /db_xref="GI:150376301"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5319208"
                     /translation="MWPRIWEECKMFTKLMAATALISASMISVASAETISMWVRSGIG
                     DSFKEVVKAYNTAHENKVELTEVPFAELVQKYATAIAGGQAPDALSLDLIYTPAFAAA
                     GQLEDLTDWAKALPYFNSLSPSHVKLGTYEDKIYGLPLTVETSIFAWNKDLYKKAGLD
                     PEKAPATWEEITANAEKIRGLGGDTYGFYFSGGGCGGCMIFTFTPLTWGAGADILSAD
                     GKTATLDTPPMRKAVDIYRNMIAKDLVPAGAASDNGVNFLSFTNGKIGQQSLGAFAIG
                     TLVTQHPEIDFGVTLIPGVDGKPSSFAGGDNFVVTKGTPKLADVKEFLEYTYSPEGQK
                     IMAKYGSLPTRGDIANEVLEGLDPRLKVGLDAIAVAKTPYTLQFNDLINSANGPWATF
                     TNAAIYGDDVDGAFADAQAEMQSIIDAGQ"
     sig_peptide     632630..632728
                     /locus_tag="Smed_4159"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.913 at
                     residue 33"
     misc_feature    632657..633883
                     /locus_tag="Smed_4159"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     misc_feature    632759..633631
                     /locus_tag="Smed_4159"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     gene            634021..634938
                     /locus_tag="Smed_4160"
                     /db_xref="GeneID:5319189"
     CDS             634021..634938
                     /locus_tag="Smed_4160"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20633 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001312898.1"
                     /db_xref="GI:150376302"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319189"
                     /translation="MTTSSLTSTTRRSRLKRKSGWRGLVYIAPAMALVTIFFVLPVLF
                     TLWMSLHKWPLLGEPAWIGLRNYTRMFTDARFFNALGFTAHYTLIVTIAIFAVAFPLA
                     LFVEKQRPLVSLYRTIVFLPVVVGLASASLLWVWLANVDSGLFAPLFAVLGLTADRIN
                     LLAKFDTAFMTIIVMVVWKIAGFTMIILLTGLQAIPRELTEAARIDGAGGWQRFRHLT
                     LPLMRRTMALALILSVTGSILAFDQFYIMTSGGPQNKMISVVYYIFNQSFVSFNLGYG
                     AALSIALLLILVTLSVVQLWLLKVGDERP"
     sig_peptide     634021..634119
                     /locus_tag="Smed_4160"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.826) with cleavage site probability 0.478 at
                     residue 33"
     misc_feature    634258..634848
                     /locus_tag="Smed_4160"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(634306..634311,634318..634323,634333..634335,
                     634363..634374,634378..634398,634450..634458,
                     634465..634470,634474..634476,634549..634554,
                     634561..634563,634567..634569,634576..634581,
                     634585..634587,634597..634602,634609..634611,
                     634660..634662,634702..634707,634714..634716,
                     634735..634746,634753..634758,634801..634806,
                     634834..634839,634846..634848)
                     /locus_tag="Smed_4160"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(634381..634398,634450..634476,634735..634752)
                     /locus_tag="Smed_4160"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(634474..634476,634534..634536,634753..634755,
                     634795..634797,634804..634806,634834..634836)
                     /locus_tag="Smed_4160"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(634612..634650,634666..634671,634681..634683)
                     /locus_tag="Smed_4160"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            634935..635798
                     /locus_tag="Smed_4161"
                     /db_xref="GeneID:5319190"
     CDS             634935..635798
                     /locus_tag="Smed_4161"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20632 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001312899.1"
                     /db_xref="GI:150376303"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319190"
                     /translation="MRTRREIRARKALRDRIAYHGIGIGAAFFFLAPFAVSFLASFRP
                     NSESGRPPLPPWPLSGLSFDAYRALDSFGSGIWQHMFNSLVVSIGTVVLTVAVSVLAG
                     YGFSRYRFPFKNALFVLIIATLMIPFQSILTPLFIILARLGLNNSLLGLMLVYVTLQL
                     PFSVFMMRNAFDAVPKEIEEAARIDGARDLRLLVRVLLPLVMPGIATVSIFAFLNAWN
                     EFFAALVLLSSNDNYTLPVLMTAVRAGRLGAINWGAVQAGVAVMVVPCLFVFLLLQRY
                     YMRGLMAGAVK"
     sig_peptide     634935..635042
                     /locus_tag="Smed_4161"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.630) with cleavage site probability 0.241 at
                     residue 36"
     misc_feature    634956..635795
                     /locus_tag="Smed_4161"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    635172..635684
                     /locus_tag="Smed_4161"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(635220..635225,635232..635237,635250..635252,
                     635280..635291,635295..635324,635331..635336,
                     635340..635342,635412..635414,635418..635420,
                     635427..635432,635436..635438,635448..635453,
                     635460..635462,635511..635513,635553..635558,
                     635565..635567,635586..635597,635604..635609,
                     635646..635651,635679..635684)
                     /locus_tag="Smed_4161"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(635298..635342,635586..635603)
                     /locus_tag="Smed_4161"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(635340..635342,635400..635402,635604..635606,
                     635640..635642,635649..635651,635679..635681)
                     /locus_tag="Smed_4161"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(635463..635501,635517..635522,635532..635534)
                     /locus_tag="Smed_4161"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            635817..637739
                     /locus_tag="Smed_4162"
                     /db_xref="GeneID:5319191"
     CDS             635817..637739
                     /locus_tag="Smed_4162"
                     /note="PFAM: protein of unknown function DUF1680;
                     KEGG: sme:SMb20631 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312900.1"
                     /db_xref="GI:150376304"
                     /db_xref="InterPro:IPR012878"
                     /db_xref="GeneID:5319191"
                     /translation="MTKTVKDRQFRPVSVPDVELGGFWGKWQDAVCQSTAETLLDRCV
                     EAGMLKAIDVSQPSPGIVIPIQPWGGTTQMFWDSDLGKSIETIAYSLYRRPNPELEAR
                     ADRIIDMYEKLQDEDGYLNAWFQRVQPHRRWTNLRDHHELYCAGHLIEAAVAYYQATG
                     KRKLLNIMCRFADYMITVFGRKEGQIPGYCGHEEIELALVRLARVTGEKKYLDLSKFF
                     IDERGTEPHFFTEEAKRDGRDPESFIQKTYEYGQAHQPVRDQKKVVGHAVRAMYLYSG
                     MADIATEYKDDSLTAALETLWDDLVTKQMYVTGGIGPAASNEGFTDYYDLPNDTAYAE
                     TCASVGLVFWASRMLGRGPDRRYADIMEQALYNGALPGLSIDGKTFFYDNPLESTGRH
                     HRWKWHHCPCCPPNIARLVTSIGSYMYAVAEDEIAVHLYGESAARLKLANGAEVELRQ
                     ATNYPWDGAIAFTARLDRPARFALSLRIPEWAAGATLSVNGSMLDLSAHLADGYARIE
                     REWSDGDRVALYLPLTLRPQYANPKVRQDVGRVALMRGPLVYCAEAADNGGDLNAIVL
                     PRELPSAETVVMEELNGAVAVDLAVEREETENWGKALYREEPAARVPHKARFVPYHLW
                     DNRAPGEMLVWVQSGR"
     misc_feature    635826..637727
                     /locus_tag="Smed_4162"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3533"
                     /db_xref="CDD:226063"
     misc_feature    635865..637469
                     /locus_tag="Smed_4162"
                     /note="Putative glycosyl hydrolase of unknown function
                     (DUF1680); Region: DUF1680; pfam07944"
                     /db_xref="CDD:219654"
     gene            637752..638837
                     /locus_tag="Smed_4163"
                     /db_xref="GeneID:5319192"
     CDS             637752..638837
                     /locus_tag="Smed_4163"
                     /note="PFAM: ABC transporter related; Transport-associated
                     OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20630 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312901.1"
                     /db_xref="GI:150376305"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5319192"
                     /translation="MANGTGNKSVVLSDIRKSYGNLEVIHGIDLTIEEGDFVVFVGPS
                     GCGKSTLLRMIAGLEEVTEGEIAIKGRDVTDLDPSERGIAMVFQSYALYPHMSVGENL
                     GFGLKMARTDPADIERRVAQVSAILKIDPLLDRRPGQLSGGQRQRVAIGRAIVRKPDV
                     FLFDEPLSNLDAELRVSMRIEIARLHRELGNTMIYVTHDQTEAMTLADQIVVLRDGRI
                     EQTGSPREVYEDPANMFVAGFIGSPRMNFLEAEWQGDGTVHIGSAALWAPIDGSSLAP
                     GDRLRLGMRPEHLTVCEPGAERIAAQVEFSEYLGGTRYLYCQLEDGQSLVVEQREGPD
                     WQVGERLSFSVPEDRRRFFAGDGRRLR"
     misc_feature    637776..638789
                     /locus_tag="Smed_4163"
                     /note="glycerol-3-phosphate transporter ATP-binding
                     subunit; Provisional; Region: ugpC; PRK11650"
                     /db_xref="CDD:236947"
     misc_feature    637779..638417
                     /locus_tag="Smed_4163"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    637875..637898
                     /locus_tag="Smed_4163"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    order(637884..637889,637893..637901,638013..638015,
                     638241..638246,638343..638345)
                     /locus_tag="Smed_4163"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    638004..638015
                     /locus_tag="Smed_4163"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    638169..638198
                     /locus_tag="Smed_4163"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    638229..638246
                     /locus_tag="Smed_4163"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    638253..638264
                     /locus_tag="Smed_4163"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    638331..638351
                     /locus_tag="Smed_4163"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     misc_feature    638595..638789
                     /locus_tag="Smed_4163"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            complement(639077..639976)
                     /locus_tag="Smed_4164"
                     /db_xref="GeneID:5319193"
     CDS             complement(639077..639976)
                     /locus_tag="Smed_4164"
                     /note="specific inhibitor of chromosomal initiation of
                     replication in vitro; binds the three 13-mers in the
                     origin (oriC) to block initiation of replication; also
                     controls genes involved in arginine transport"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome replication initiation inhibitor
                     protein"
                     /protein_id="YP_001312902.1"
                     /db_xref="GI:150376306"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR001719"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5319193"
                     /translation="MLDYSALRAVSAVVQTGSFEKAAGLLNVTPSAVSQRVKQFEERL
                     GVVLIARGNPCTATEKGEWLCRHMENVGMLEAELFQHLPDLLDPTDPEPRVTLHIATN
                     ADSLGTWFLTAMSSFARHSPYLLNIAIDDEDHTAEWLRRGRVVAAVTSLEKPVQGCRR
                     LFLGALRYHATASPDFVARHFPQGVTANSIGRAPALTFNQKDRLQCRWIRQVFEEDAN
                     PATHWLPSTPGFIEASLSGMGWGMNPAPLVREHLSSGRLVELIPETPLDVPLYWQLNR
                     LAADRLAELTREVTTAARHHLLG"
     misc_feature    complement(639086..639976)
                     /locus_tag="Smed_4164"
                     /note="chromosome replication initiation inhibitor
                     protein; Validated; Region: PRK03635"
                     /db_xref="CDD:235144"
     misc_feature    complement(639791..639961)
                     /locus_tag="Smed_4164"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    complement(639110..639691)
                     /locus_tag="Smed_4164"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cl11398"
                     /db_xref="CDD:245600"
     misc_feature    complement(order(639269..639274,639278..639283,
                     639299..639316,639584..639604,639611..639613,
                     639623..639625,639632..639637,639641..639646))
                     /locus_tag="Smed_4164"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            640071..640682
                     /locus_tag="Smed_4165"
                     /db_xref="GeneID:5319194"
     CDS             640071..640682
                     /locus_tag="Smed_4165"
                     /note="PFAM: Lysine exporter protein (LYSE/YGGA);
                     KEGG: rle:RL2856 putative transmembrane lysine/arginine
                     export protein"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine exporter protein LysE/YggA"
                     /protein_id="YP_001312903.1"
                     /db_xref="GI:150376307"
                     /db_xref="InterPro:IPR001123"
                     /db_xref="GeneID:5319194"
                     /translation="MNIPVFGTGLVTGLSLIVAIGAQNAFVLRQGLRNEHVFAVCLIC
                     GLSDALLITLGVTSFRQIAALLPWLDPIMRYGGAAFLIWYGAKSLYSALRSSEALAVQ
                     EGAGSASVRTVLLTCLALTWLNPHVYLDTVVLLGTISTRFPGYEASFAAGAVTGSLLF
                     FFSLGYGATWLRPIFSKPASWRILETFITLTMWLIAFNLLRDL"
     sig_peptide     640071..640148
                     /locus_tag="Smed_4165"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.685) with cleavage site probability 0.343 at
                     residue 26"
     misc_feature    640074..640676
                     /locus_tag="Smed_4165"
                     /note="Lysine efflux permease [General function prediction
                     only]; Region: COG1279"
                     /db_xref="CDD:224198"
     gene            640761..641399
                     /locus_tag="Smed_4166"
                     /db_xref="GeneID:5319195"
     CDS             640761..641399
                     /locus_tag="Smed_4166"
                     /note="PFAM: Lysine exporter protein (LYSE/YGGA);
                     KEGG: mlo:mll6377 threonine efflux protein"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine exporter protein LysE/YggA"
                     /protein_id="YP_001312904.1"
                     /db_xref="GI:150376308"
                     /db_xref="InterPro:IPR001123"
                     /db_xref="GeneID:5319195"
                     /translation="MSAQFHHLLIVYAAYVIAAGSPGPSNMQIMAVAMHSGRRAALIL
                     AAGVVSGSFFWGAMAATGVSAVLTRYAEALIVLKIFGGLYLLYLAFKAGKSALASDPQ
                     TASNSSRNGAVPTAAELYRRGLLMHLSNPKSILAWIALVTLGLGPGSSWHTLGAILGG
                     CAVLSVTIFCGYAIVFSTAPMVRLYRRARRWIEGVLALFFGFAGLRLLLSRI"
     misc_feature    640773..641333
                     /locus_tag="Smed_4166"
                     /note="Putative threonine efflux protein [Amino acid
                     transport and metabolism]; Region: RhtB; COG1280"
                     /db_xref="CDD:224199"
     gene            641448..642338
                     /locus_tag="Smed_4167"
                     /db_xref="GeneID:5319196"
     CDS             641448..642338
                     /locus_tag="Smed_4167"
                     /note="PFAM: dihydrodipicolinate synthetase;
                     KEGG: mlo:mll6376 dihydrodipicolinate synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthetase"
                     /protein_id="YP_001312905.1"
                     /db_xref="GI:150376309"
                     /db_xref="InterPro:IPR002220"
                     /db_xref="GeneID:5319196"
                     /translation="MTLFAGLAAFSITPADASGHVDTAALARLLERICAAGAESIGLL
                     GSTGGYAFLSRRERQRAVEAAIECVDGRIPVIVGVGALRTDEAQALARDARKAGASGL
                     LLAPMSYTPLTDEEVLQHISAVAEAGQLPLCIYNNPSTTRFTFTDDLIVRLARLPNIA
                     AVKMPLPAQGDVAGELARMRSRIPEGFSIGYSGDWGAADALLAGCDAWYSVVAGLMPA
                     EAVALTRAARAGDVAEARRLDRAFQPLWNLFKEFGSFRVMYAMADLLGLVGVDPPRPI
                     LPLGKTDMARVKDALTRIAL"
     misc_feature    641448..642320
                     /locus_tag="Smed_4167"
                     /note="Dihydrodipicolinate synthase/N-acetylneuraminate
                     lyase [Amino acid transport and metabolism / Cell envelope
                     biogenesis, outer membrane]; Region: DapA; COG0329"
                     /db_xref="CDD:223406"
     sig_peptide     641448..641507
                     /locus_tag="Smed_4167"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.834) with cleavage site probability 0.648 at
                     residue 20"
     misc_feature    641472..642320
                     /locus_tag="Smed_4167"
                     /note="Dihydrodipicolinate synthase family; Region:
                     DHDPS-like; cd00408"
                     /db_xref="CDD:188630"
     misc_feature    order(641475..641477,641571..641573,641580..641588,
                     641850..641852,641934..641936)
                     /locus_tag="Smed_4167"
                     /note="inhibitor site; inhibition site"
                     /db_xref="CDD:188630"
     misc_feature    order(641571..641573,641580..641588,641850..641852,
                     641934..641936,642072..642074)
                     /locus_tag="Smed_4167"
                     /note="active site"
                     /db_xref="CDD:188630"
     misc_feature    order(641583..641585,641598..641603,641694..641699,
                     641769..641774,641793..641795,641805..641807,
                     642267..642272)
                     /locus_tag="Smed_4167"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188630"
     misc_feature    641934..641936
                     /locus_tag="Smed_4167"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188630"
     gene            complement(642350..643339)
                     /locus_tag="Smed_4168"
                     /db_xref="GeneID:5319197"
     CDS             complement(642350..643339)
                     /locus_tag="Smed_4168"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type;
                     KEGG: sme:SMb20626 putative transcriptional regulator,
                     AraC family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="YP_001312906.1"
                     /db_xref="GI:150376310"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="GeneID:5319197"
                     /translation="MLDHSSKTSSSASEDFLTELLRGLRLDGVDYVRCELTAPWGISF
                     PAQETARFHFICGDCWLRVADGDWIELKRGDAVLLPRGGEHALASMPGEKLAPLDAYS
                     VQEVCHCVYNVCGGGRGETTILFCGSLRFNMDSMHPLLRMMPDVMRINALTASEPAIP
                     HMLDAMAREVGASRVGSGGVLARLADVLAALIIRSWVEHGCGNTSGWVAAVRHPGLGR
                     VIAAMHLDPEKAWTVDSLARLMGASRSGFAQQFASVVGETPARYLAQVRMHQARQWLT
                     RDRMRISVVARRLGYDSEASFSRAFKRVIGQPPSHYRGADPAEVSTFAGESRP"
     misc_feature    complement(642809..643297)
                     /locus_tag="Smed_4168"
                     /note="Cupin; Region: Cupin_6; pfam12852"
                     /db_xref="CDD:221809"
     misc_feature    complement(642551..642673)
                     /locus_tag="Smed_4168"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     misc_feature    complement(642401..642649)
                     /locus_tag="Smed_4168"
                     /note="helix_turn_helix, arabinose operon control protein;
                     Region: HTH_ARAC; smart00342"
                     /db_xref="CDD:197666"
     misc_feature    complement(642401..642508)
                     /locus_tag="Smed_4168"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     gene            643415..644620
                     /locus_tag="Smed_4169"
                     /db_xref="GeneID:5319198"
     CDS             643415..644620
                     /locus_tag="Smed_4169"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: sme:SMb20625 drug:H+ antiporter-1, DHA1 family"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001312907.1"
                     /db_xref="GI:150376311"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5319198"
                     /translation="MTDTATTLDAALIPETNERIDPAWSGVGSLALGVFGLVTAEFLP
                     VSILTPMAADLGISTGTAGQAVTATAVVGAVAGLTVAIATRRFDRRLVLWGFTLALIV
                     SSLIAAFATNLAMLLTARVILGVGLGGFWSMMAAIALRLVPMSLVPRAMSIVFTGVSV
                     ATVCAAPIGAYIGDLWGWRAAFLMAAAVGAVTLIVQMVSIPRLPPQSAPSLKLLFDLL
                     GRPSIRIGIITVLLFVSGHFAGFTYVRPFLEKVPEFGIEAISLILLAYGIGGFFGNIA
                     GGLIIERSITAAVGLATLLIAAMAFLLVTFGSLDVVSATAVTIWGFAFGALPVAVQTW
                     MVRAAPEHAESTGGLIVATFQVGIASGAVLGGLFVDAFGPLGAITYCAAATFASALYV
                     ATSRRSIGV"
     misc_feature    643478..644608
                     /locus_tag="Smed_4169"
                     /note="Arabinose efflux permease [Carbohydrate transport
                     and metabolism]; Region: AraJ; COG2814"
                     /db_xref="CDD:225371"
     misc_feature    643670..644593
                     /locus_tag="Smed_4169"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    order(643793..643798,643805..643810,643817..643822,
                     643829..643831,643865..643870,643877..643882,
                     643898..643900,644114..644116,644123..644128,
                     644135..644140,644147..644149,644189..644191,
                     644201..644203,644213..644215,644222..644224,
                     644234..644236,644375..644377,644384..644389,
                     644396..644398,644408..644413,644420..644422,
                     644453..644455,644462..644467,644474..644479,
                     644486..644488)
                     /locus_tag="Smed_4169"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(644887..645492)
                     /gene="thiE"
                     /locus_tag="Smed_4170"
                     /db_xref="GeneID:5318579"
     CDS             complement(644887..645492)
                     /gene="thiE"
                     /locus_tag="Smed_4170"
                     /EC_number="2.5.1.3"
                     /note="Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole
                     monophosphate and 4-amino-5-hydroxymethyl pyrimidine
                     pyrophosphate to form thiamine monophosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate pyrophosphorylase"
                     /protein_id="YP_001312908.1"
                     /db_xref="GI:150376312"
                     /db_xref="InterPro:IPR003733"
                     /db_xref="GeneID:5318579"
                     /translation="MKLDPFYLIVNSAAWIERLVPLGVKLVQLRVKDLGADDIRSQIR
                     LAKAVCSAHACQLIVNDYWRLAIEEGCDFVHLGQEDLADADLGAIRAAGLKLGLSTHD
                     EAELETALAAGPDYIALGPIYPTILKKMKWAPQGLERLSTWRDRMGRLPLVAIGGLNP
                     ERIEGVFAHGADSAAVVTDITLNADPEARTREWIQRTDRRR"
     misc_feature    complement(644908..645477)
                     /gene="thiE"
                     /locus_tag="Smed_4170"
                     /note="Thiamine monophosphate synthase (TMP
                     synthase)/TenI. TMP synthase catalyzes an important step
                     in the thiamine biosynthesis pathway, the substitution of
                     the pyrophosphate of 2-methyl-4-amino-5-
                     hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-;
                     Region: TMP_TenI; cd00564"
                     /db_xref="CDD:238317"
     misc_feature    complement(order(644959..644970,645022..645024,
                     645034..645036,645112..645114,645118..645120,
                     645139..645141,645145..645147,645196..645198,
                     645268..645270,645403..645405,645409..645411,
                     645466..645468,645472..645474))
                     /gene="thiE"
                     /locus_tag="Smed_4170"
                     /note="thiamine phosphate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238317"
     misc_feature    complement(order(644959..644964,645022..645024,
                     645109..645114,645118..645120,645196..645198,
                     645253..645255,645310..645315,645397..645399,
                     645403..645405,645409..645411))
                     /gene="thiE"
                     /locus_tag="Smed_4170"
                     /note="active site"
                     /db_xref="CDD:238317"
     misc_feature    complement(order(645109..645111,645196..645198,
                     645253..645255,645262..645264,645310..645315,
                     645397..645399,645403..645405))
                     /gene="thiE"
                     /locus_tag="Smed_4170"
                     /note="pyrophosphate binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238317"
     gene            complement(645489..646262)
                     /gene="thiG"
                     /locus_tag="Smed_4171"
                     /db_xref="GeneID:5318580"
     CDS             complement(645489..646262)
                     /gene="thiG"
                     /locus_tag="Smed_4171"
                     /note="functions in thiamine (vitamin B1) biosynthesis; in
                     Bacillus subtilis this enzyme catalyzes the formation of
                     thiazole from dehydroxyglycine and
                     1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate"
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="YP_001312909.1"
                     /db_xref="GI:150376313"
                     /db_xref="InterPro:IPR008867"
                     /db_xref="GeneID:5318580"
                     /translation="MPLFYGTEIRSRLLLGTARYPSPAVLAEAVRRSRTDIVTVSLRR
                     ETAGGRQGGAFFELIRELGVRVLPNTAGCHSVAEAVLTAKMARDVFETDWIKLEVIGH
                     QDTLQPDVFGLVEGAGILTGEGFEVFPYTTDDLVVAERLLEAGCKVLMPWCAPIGSAM
                     GPQNMQGLRAMRAEFPDVPLIVDAGIGRPSHATTVMELGYDAVLLNTAVAGAADPAAM
                     AEAFAMAIDAGYAAHGAGMLEPRDMAVPSTPVIGKAVFS"
     misc_feature    complement(645513..646250)
                     /gene="thiG"
                     /locus_tag="Smed_4171"
                     /note="Thiazole synthase (ThiG) is the tetrameric enzyme
                     that is involved in the formation of the thiazole moiety
                     of thiamin pyrophosphate, an essential ubiquitous cofactor
                     that plays an important role in carbohydrate and amino
                     acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728"
                     /db_xref="CDD:240079"
     misc_feature    complement(order(646092..646094,646101..646103,
                     646140..646142))
                     /gene="thiG"
                     /locus_tag="Smed_4171"
                     /note="ThiS interaction site; other site"
                     /db_xref="CDD:240079"
     misc_feature    complement(order(645714..645716,645969..645971,
                     645975..645977))
                     /gene="thiG"
                     /locus_tag="Smed_4171"
                     /note="putative active site [active]"
                     /db_xref="CDD:240079"
     misc_feature    complement(order(645516..645518,645522..645530,
                     645534..645536,645540..645545,645549..645563,
                     645567..645572,645579..645581,645600..645602,
                     645609..645614,645621..645629,645642..645644,
                     645669..645674,645681..645683,645693..645701,
                     645744..645746,645756..645758,645774..645776,
                     645783..645791,645843..645848,645855..645863,
                     645867..645869,645936..645944,645951..645953,
                     645960..645962))
                     /gene="thiG"
                     /locus_tag="Smed_4171"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:240079"
     gene            complement(646265..646462)
                     /locus_tag="Smed_4172"
                     /db_xref="GeneID:5318581"
     CDS             complement(646265..646462)
                     /locus_tag="Smed_4172"
                     /note="with ThiF, ThiG, and ThiO catalyzes the formation
                     of the thiazole moiety of thiamine pyrophosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="YP_001312910.1"
                     /db_xref="GI:150376314"
                     /db_xref="InterPro:IPR003749"
                     /db_xref="InterPro:IPR010035"
                     /db_xref="GeneID:5318581"
                     /translation="MKLTINGEEHEVQADTLAELLQYLEFEGDWLATAVNGELVQKAE
                     RADRRLQDSDRIEVLSPMQGG"
     misc_feature    complement(646268..646459)
                     /locus_tag="Smed_4172"
                     /note="ThiaminS ubiquitin-like sulfur carrier protein;
                     Region: ThiS; cd00565"
                     /db_xref="CDD:176353"
     misc_feature    complement(order(646286..646294,646346..646348))
                     /locus_tag="Smed_4172"
                     /note="thiS-thiF/thiG interaction site; other site"
                     /db_xref="CDD:176353"
     gene            complement(646431..647435)
                     /locus_tag="Smed_4173"
                     /db_xref="GeneID:5318582"
     CDS             complement(646431..647435)
                     /locus_tag="Smed_4173"
                     /note="TIGRFAM: glycine oxidase ThiO;
                     PFAM: FAD dependent oxidoreductase;
                     KEGG: sme:SMb20616 putative thiamine biosynthesis
                     oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine oxidase ThiO"
                     /protein_id="YP_001312911.1"
                     /db_xref="GI:150376315"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR012727"
                     /db_xref="GeneID:5318582"
                     /translation="MRVLIRGAGVAGLTAAHELLARGAEVTVIENAEGFGRAASWYAG
                     GMLAPWCERESAEEAVLTRGIGAADWWEAALPAGSVHRNGTLVVAQPRDGAELRRFAA
                     RTCGFRWLNAEEIGALEPALAGRFRQALFFPDEAHLDPRRALSALRQRLAARGVTFVA
                     EEPDGRGAVLTVDCTGAARIGGIDGLRGVRGEMLYLATDEVSLSRPVRMLHPRIPLYI
                     VPRNGGLFMCGATMIESDEAGPITARSLMELLNAAYALHPAFAEARLVETGTGVRPAF
                     ADNLPRAVRRESTITVNGLYRHGFLLSPAMAGDVAALALGERYPEEMSDETYDQWRGT
                     "
     misc_feature    complement(<647283..647417)
                     /locus_tag="Smed_4173"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; pfam13450"
                     /db_xref="CDD:205628"
     misc_feature    complement(646485..647387)
                     /locus_tag="Smed_4173"
                     /note="glycine oxidase ThiO; Region: thiamin_ThiO;
                     TIGR02352"
                     /db_xref="CDD:233831"
     gene            complement(647437..649269)
                     /locus_tag="Smed_4174"
                     /db_xref="GeneID:5318583"
     CDS             complement(647437..649269)
                     /locus_tag="Smed_4174"
                     /note="required for the synthesis of the
                     hydromethylpyrimidine moiety of thiamine"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiC"
                     /protein_id="YP_001312912.1"
                     /db_xref="GI:150376316"
                     /db_xref="InterPro:IPR002817"
                     /db_xref="GeneID:5318583"
                     /translation="MNLFKPLGATPSVTQGPLPASQKVYRPGDIHPDIRVPMREITLH
                     PTSGEPPVTVYDASGPYTLENADIRIDAGLPRLRHDWILKRGGVESYEGRAVKAEDNG
                     FASGERLTPEFPVRNQPLRAKPGQAVTQIAFARAGIITPEMEFIAIRENLGRKAAKEV
                     LTRDGESFGASVPDFVTPEFVRQEVAAGRAIIPANINHPESEPMIIGRNFLVKINANI
                     GNSAVTSSMAEEVEKMVWATRWGADTVMDLSTGRNIHNIREWIIRNSPVPIGTVPLYQ
                     ALEKVNGIAEDLSWEVFRDTLIEQAEQGVDYFTIHAGVRLHYIPLTVDRVTGIVSRGG
                     SIMAKWCLHHHQESFLYEHFEEICDICRAYDVSFSLGDGLRPGSIADANDRAQFAELE
                     TLGELTQIAWARDCQVMIEGPGHVPMHKIKENMDKQLAVCGEAPFYTLGPLTTDIAPG
                     YDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRNDVKMGVITYKIAAHAADLAKGH
                     PAARIRDDALSRARFEFRWEDQFNLSLDPETARNFHDETLPKEAHKVAHFCSMCGPKF
                     CSMRISHDIRAEAQKEGLEAMAAKYRDGGDLYMPVDGSDAPTGE"
     misc_feature    complement(647467..649242)
                     /locus_tag="Smed_4174"
                     /note="thiamine biosynthesis protein ThiC; Provisional;
                     Region: PRK09284"
                     /db_xref="CDD:236451"
     misc_feature    complement(649003..649224)
                     /locus_tag="Smed_4174"
                     /note="ThiC-associated domain; Region: ThiC-associated;
                     pfam13667"
                     /db_xref="CDD:222303"
     misc_feature    complement(647533..648894)
                     /locus_tag="Smed_4174"
                     /note="Thiamine biosynthesis protein ThiC [Coenzyme
                     metabolism]; Region: ThiC; COG0422"
                     /db_xref="CDD:223499"
     misc_binding    complement(649368..649479)
                     /note="TPP riboswitch (THI element) as predicted by Rfam
                     (RF00059), score 82.00"
                     /bound_moiety="thiamin/thiaminpyrophosphate"
     gene            649675..651678
                     /locus_tag="Smed_4175"
                     /db_xref="GeneID:5318584"
     CDS             649675..651678
                     /locus_tag="Smed_4175"
                     /note="KEGG: sme:SMb20614 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312913.1"
                     /db_xref="GI:150376317"
                     /db_xref="GeneID:5318584"
                     /translation="MGQAETRTGKRAALWAAVALIAIAAAGMTGYKIVAERTMSGMIA
                     ERGGKVGNVEADFLGRIHLRDVKLPLKDGSEVHIAAIDGRPEIFFLKGMLEVAGLQLK
                     TKLGSVEVPQATVQEANLSYGTTTEIFGGRGDLPLSKRIELFAARRVVAPEILVTQTV
                     GGSEQKLVYRNVVSEGIADGRVSRFSAEGASFEFGVDGNGGEAGGKKRLTGSLGPMTV
                     QDMDAAYLARLYTEKAGPQDKEAKPVYGPSSVKDIVFSDGEARFGYAEIRSSGISMAM
                     TDQPLLETLNALSAVSAPDELPPAERQAYFTRILSIIDMTKKADIEMLGLNMEVPAKD
                     GDKGKKIKFATDRLAIQLDGQTLDATLNGLSMAEGESHFKISEAALSGFSWSPTFKAL
                     EQMVALDEQQLESFPFTTLLPEFGTVRLAGIDADLPGSVENGETSPSTAERVRFSLKE
                     YEAALTKPRNGIPTDIRVSYQDLTVPVPANIEEKTLAELRKLGIDELVLSSSLEAAWD
                     EAQQTLVIKEISTSLKDLAGFSFSGVMGGVSGDFFSGDEAKMRVALFGLTAREAELEI
                     EDKGLAAKGLKAYAEQNGMTEDQARGMLTMTSSVVLQQFADEEPRLQDVVDAVSKFIA
                     KPGTFTLTVKSKSPSGLGALELAVASQNPLLLLDRVDIEAVAE"
     sig_peptide     649675..649755
                     /locus_tag="Smed_4175"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.916) with cleavage site probability 0.540 at
                     residue 27"
     gene            complement(651820..653178)
                     /locus_tag="Smed_4176"
                     /db_xref="GeneID:5318585"
     CDS             complement(651820..653178)
                     /locus_tag="Smed_4176"
                     /note="PFAM: response regulator receiver; sigma-54 factor
                     interaction domain-containing protein; helix-turn-helix
                     Fis-type; ATPase associated with various cellular
                     activities AAA_5;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20613 C4-dicarboxylate transport
                     transcriptional regulatory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="two component, sigma54 specific, Fis family
                     transcriptional regulator"
                     /protein_id="YP_001312914.1"
                     /db_xref="GI:150376318"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR002078"
                     /db_xref="InterPro:IPR002197"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011704"
                     /db_xref="GeneID:5318585"
                     /translation="MRAAPTVFLIDDDRDLRKAMQQTLELAGFTVSPFASAAEALGEL
                     TADFAGVVISDIRMPGMDGLTLFRKVLALDPDLPMILVTGHGDIPMAVQAIQDGAYDF
                     IAKPFAADRLVQSARRAEEKRRLVMEIRALRRTAEAASEGLPLIGQTPAMERLRQTLK
                     HIADTDVDVLVAGETGSGKEVVATLLHHWSRRRSGNFVALNCGALPETVIESELFGHE
                     PGAFTGAVKKRIGRIEHASGGTLFLDEIEAMPPATQVKMLRVLEAREITPLGTNLTRP
                     VDIRVVAAAKVDLGDPAERGDFREDLFYRLNVVTLSIPPLRERRDDIPLLFSHFLARA
                     AERFGRDVPAIPSAVRDHLAAHSWPGNVRELSHFAERVALGVEGTLGAAAAAPVSGGA
                     TLPERLERYEANILKEALTAHRGDVRETLRALGIPRKTFYDKLQRHGINRTDYVKERG
                     PA"
     misc_feature    complement(651835..653178)
                     /locus_tag="Smed_4176"
                     /note="Response regulator containing CheY-like receiver,
                     AAA-type ATPase, and DNA-binding domains [Signal
                     transduction mechanisms]; Region: AtoC; COG2204"
                     /db_xref="CDD:225114"
     misc_feature    complement(652822..653157)
                     /locus_tag="Smed_4176"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(652861..652866,652873..652875,
                     652930..652932,652990..652992,653014..653016,
                     653143..653148))
                     /locus_tag="Smed_4176"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(653014..653016)
                     /locus_tag="Smed_4176"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(652990..652998,653002..653007))
                     /locus_tag="Smed_4176"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(652858..652866)
                     /locus_tag="Smed_4176"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(652252..652743)
                     /locus_tag="Smed_4176"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(652639..652662)
                     /locus_tag="Smed_4176"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(652306..652308,652447..652449,
                     652636..652659))
                     /locus_tag="Smed_4176"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(652444..652461)
                     /locus_tag="Smed_4176"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(652264..652266)
                     /locus_tag="Smed_4176"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(651865..651990)
                     /locus_tag="Smed_4176"
                     /note="Bacterial regulatory protein, Fis family; Region:
                     HTH_8; pfam02954"
                     /db_xref="CDD:202485"
     gene            complement(653182..655044)
                     /locus_tag="Smed_4177"
                     /db_xref="GeneID:5318586"
     CDS             complement(653182..655044)
                     /locus_tag="Smed_4177"
                     /note="PFAM: ATP-binding region ATPase domain protein;
                     histidine kinase A domain protein;
                     KEGG: sme:SMb20612 C4-dicarboxylate transport sensor
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="YP_001312915.1"
                     /db_xref="GI:150376319"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="GeneID:5318586"
                     /translation="MHNTGMSKHADMEDPAALRSRARRSWLVFAAVALVLVAAGLLFA
                     RDYGRSRALFSLAGQSRIDASLKASLLRAVVERQRALPLVLADDAAIRGALLTPDRQS
                     LDRINRKLEGLATSAEAAVIYLIDRNGTAIAASNWRDSTSFVGNDYAFRDYFRLAMRD
                     GMAEHFAMGTVSKRPGLYISRRVAGPGGPLGVIVAKLEFDGVEADWQASGKPAYVTDR
                     RGIVLITSMPSWRFMTTKPIARERLAPIRESLQFGDAPLLPLPFRKVEARPDGSSTLD
                     ALLPGEANAAFLRVETMVPSTNWRLEQLSPLKAPLAAGAREAQLITLAALVPLLGLAA
                     YLLRRRQVIAMRSAEERLARSKLETSVEERTRDLRMARDRLETEIADHRQTTEKLQAV
                     QQDLVQANRLAILGQVAAGVAHEINQPVATIRAYADNARTFLERGQSATAAENMESIA
                     ELTERVGAITDELRRFARKGHFAAGPTAMKDVIEGALMLLRSRFAGRMDAIRIDLPPD
                     GLQVFGNRIRLEQVLINLLQNALEAIGDSGNGAIKVSCEETATAVTLTVADNGPGIPA
                     DVREELFTPFNTSKEDGLGLGLAISKEIVSDYGGTIEVASSPSGTTFIVNLMKA"
     sig_peptide     complement(654910..655044)
                     /locus_tag="Smed_4177"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.769) with cleavage site probability 0.767 at
                     residue 45"
     misc_feature    complement(653185..654912)
                     /locus_tag="Smed_4177"
                     /note="Signal transduction histidine kinase regulating
                     C4-dicarboxylate transport system [Signal transduction
                     mechanisms]; Region: COG4191"
                     /db_xref="CDD:226654"
     misc_feature    complement(653641..653841)
                     /locus_tag="Smed_4177"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    complement(order(653656..653658,653668..653670,
                     653677..653679,653689..653691,653698..653700,
                     653710..653712,653767..653769,653776..653778,
                     653788..653790,653797..653799,653809..653811,
                     653821..653823))
                     /locus_tag="Smed_4177"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    complement(653803..653805)
                     /locus_tag="Smed_4177"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    complement(653194..653490)
                     /locus_tag="Smed_4177"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(653206..653208,653212..653217,
                     653227..653229,653233..653235,653281..653292,
                     653353..653358,653362..653364,653368..653370,
                     653374..653376,653449..653451,653458..653460,
                     653470..653472))
                     /locus_tag="Smed_4177"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(653458..653460)
                     /locus_tag="Smed_4177"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(653284..653286,653290..653292,
                     653356..653358,653362..653364))
                     /locus_tag="Smed_4177"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            655239..656603
                     /locus_tag="Smed_4178"
                     /db_xref="GeneID:5318587"
     CDS             655239..656603
                     /locus_tag="Smed_4178"
                     /note="involved in the transport of C4-dicarboxylates
                     across the membrane"
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate transporter DctA"
                     /protein_id="YP_001312916.1"
                     /db_xref="GI:150376320"
                     /db_xref="InterPro:IPR001991"
                     /db_xref="GeneID:5318587"
                     /translation="MLPDWACHVEDIMIIEHSAEVRGKTPLYRHLYVQVLAAIAAGIL
                     LGHFYPDIGTQLKPLGDAFIRLVKMIIAPVIFLTVATGIAGMTDLAKVGRVAGKAMIY
                     FLAFSTLALLVGLVVANLVQPGAGMHIDPASLDAKAVATYAQKAHEQSITGFLMNIIP
                     TTLVGAFAEGDILQVLFISVLFGISLAIVGKKAEPVVDFLQALTLPIFRLVAILMKAA
                     PIGAFGAMAFTIGKYGIASIANLAMLIGTFYLTSFLFVFVVLGAVARYNGFSILSLVR
                     YIKEELLLVLGTSSSEAALPGLMNKMEKAGCKRSVVGLVIPTGYSFNLDGTNIYMTLA
                     ALFIAQATDTPLSYGDQILLLLVAMLSSKGAAGITGAGFITLAATLSVVPSVPVAGMA
                     LILGIDRFMSECRALTNFVGNAVATIVVAKWEGELDQAQLSAALGGEMQVETIPAVVV
                     QPAE"
     misc_feature    655305..656588
                     /locus_tag="Smed_4178"
                     /note="C4-dicarboxylate transporter DctA; Reviewed;
                     Region: PRK01663"
                     /db_xref="CDD:234968"
     misc_feature    655308..656528
                     /locus_tag="Smed_4178"
                     /note="Na+/H+-dicarboxylate symporters [Energy production
                     and conversion]; Region: GltP; COG1301"
                     /db_xref="CDD:224220"
     gene            complement(656696..657625)
                     /locus_tag="Smed_4179"
                     /db_xref="GeneID:5319345"
     CDS             complement(656696..657625)
                     /locus_tag="Smed_4179"
                     /note="PFAM: regulatory protein LuxR; response regulator
                     receiver; Sigma-70 region 4 type 2;
                     KEGG: sme:SMb20610 putative two-component response
                     regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver protein"
                     /protein_id="YP_001312917.1"
                     /db_xref="GI:150376321"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR013249"
                     /db_xref="GeneID:5319345"
                     /translation="MPVPEAANARDIVLLVDDSPEALGFLTEALEQSGFSVLIATSGN
                     AALNIADRITPDIILLDAVMPGMDGFDTCARLKANASVAQVPVVFMTGLTETEHVVRA
                     LESGGVDYLTKPINIDELRARIRVHLSNARSAQSARVALDAAGRHLLAVRGDGTVRWS
                     TPQATRLVNAATGSDDGLFFVAGRIAEWMREREKGTGERHGSFTLQRAAQTGLQISYL
                     GAIGANEFLFRLTTENGMSDDETLRQHFQLTPRESEVLLWIAKGKSNRDIGEILGLSS
                     RTVTKHLEQIYVKLGVENRASAAVKATQVLHGI"
     misc_feature    complement(657251..657589)
                     /locus_tag="Smed_4179"
                     /note="Response regulator receiver domain; Region:
                     Response_reg; pfam00072"
                     /db_xref="CDD:200976"
     misc_feature    complement(657242..657586)
                     /locus_tag="Smed_4179"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(657284..657289,657296..657298,
                     657353..657355,657419..657421,657443..657445,
                     657572..657577))
                     /locus_tag="Smed_4179"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(657443..657445)
                     /locus_tag="Smed_4179"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(657419..657427,657431..657436))
                     /locus_tag="Smed_4179"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(657281..657289)
                     /locus_tag="Smed_4179"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(656720..656884)
                     /locus_tag="Smed_4179"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(656741..656743,656774..656788,
                     656792..656797,656801..656806,656828..656836,
                     656873..656881))
                     /locus_tag="Smed_4179"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(656726..656728,656735..656743,
                     656834..656836,656840..656842,656846..656848))
                     /locus_tag="Smed_4179"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(657612..660992)
                     /locus_tag="Smed_4180"
                     /db_xref="GeneID:5319346"
     CDS             complement(657612..660992)
                     /locus_tag="Smed_4180"
                     /note="PFAM: response regulator receiver; ATP-binding
                     region ATPase domain protein; histidine kinase A domain
                     protein;
                     KEGG: sme:SMb20609 putative two-component sensor histidine
                     kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane sensor hybrid histidine
                     kinase"
                     /protein_id="YP_001312918.1"
                     /db_xref="GI:150376322"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="GeneID:5319346"
                     /translation="MAARQRIIPVRREYNRWVADQTLEDYALRFTAKSARRFSSARIS
                     QTAIGAISFLALEAIGGAITMSYGTTNAIVAILVASLMILIVGLPISRYAIRHGVDID
                     LLTRGASFGYIGSTITSLIYASFTFILFAIEASIMSGALELALGVPLWAGYIVSAVVV
                     IPLVTHGVRLISRFQLVTQPFWIVLNILPFAFIALADWEKVGLWLAYAGIHHTSGPSG
                     TVAPFDLIEFGAASAVIFALMAQIGEQVDFLRFLPPDGQRKLRHRIAVFLAGSGWVIV
                     GAPKLLAGSFLVVLALSAGVPSTRAADPAQMYYTAFGYIVPYETAALLLMAAFVVVSQ
                     LKINVMNAYAGSLAWSNFFSRLTHSHPGRVIWLVFNVAIALLLMELGIYRLLEETLGI
                     FSIIAMAWLCTISADLFVNKPLGLAPAGIEFKRAHLYDINPVGLGTMGVSTLFALVAH
                     FGAMGEIASSLAPFIALATAFLVSPLIAWWTEGKFYLARKPRKSWFSESEITCSICEH
                     PFEPEDMAWCPAYAAPICSLCCSLDGRCHDMCKPKARLSFQIATVAKALLPETVVAKL
                     ATRLGRYAIAAVISITGIGAILAMIAHQTTAASPETAAVVERTVAIVFFVFAILAGIV
                     SWFYVLAHDSRVVAEEESSRQNTALLKEIAAHKKTDAALQDAKERAEAANRAKSRYVV
                     GLSHELRTPLNAVLGYAQILERDETIPPSRQNAIKAIRRSADHLSGLIDGLLDISKIE
                     AGKLQVYSNEINIQDFLDQIVDMFRPQAQAKGITFEHSRAAALPQYVRTDDKRLRQIL
                     VNLLSNALKFTERGHIRFDVAYRSQVASFTVEDSGRGISERDLPKIFEPFQRGEAEYR
                     MPGLGLGLTITRLLTQTLGGEISVTSERDKGTVFKVRLMLSAVDRPAARKDAVRKIRS
                     YQGPHRAIVVVDDNPEHRELMREVLTPLDFTVIPAASGADCLTLIEDTKPDLFLIDIS
                     MPGMNGWDLVTRLREAGQTAPAIMLSANIGDGSAAGAFGHNDTLAKPFRVRQLTDKLA
                     IQLGLEWIYDDGPKETRGPDKAGAVISPGNHHIRELIELGEIGYVRGIEAKLTEIALN
                     PDNRAFAEEARAYVQAFDLSGYDAFLKRLLAGEANARA"
     misc_feature    complement(659553..660848)
                     /locus_tag="Smed_4180"
                     /note="Solute carrier families 5 and 6-like; solute
                     binding domain; Region: SLC5-6-like_sbd; cl00456"
                     /db_xref="CDD:241874"
     misc_feature    complement(658284..>658961)
                     /locus_tag="Smed_4180"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: BaeS; COG0642"
                     /db_xref="CDD:223715"
     misc_feature    complement(658779..658946)
                     /locus_tag="Smed_4180"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    complement(order(658794..658796,658806..658808,
                     658815..658817,658827..658829,658836..658838,
                     658848..658850,658899..658901,658908..658910,
                     658920..658922,658929..658931,658941..658943))
                     /locus_tag="Smed_4180"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    complement(658935..658937)
                     /locus_tag="Smed_4180"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    complement(658311..658613)
                     /locus_tag="Smed_4180"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(658323..658325,658329..658334,
                     658347..658349,658353..658355,658401..658412,
                     658485..658490,658494..658496,658500..658502,
                     658506..658508,658572..658574,658581..658583,
                     658593..658595))
                     /locus_tag="Smed_4180"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(658581..658583)
                     /locus_tag="Smed_4180"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(658404..658406,658410..658412,
                     658488..658490,658494..658496))
                     /locus_tag="Smed_4180"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(657906..658229)
                     /locus_tag="Smed_4180"
                     /note="Response regulator receiver domain; Region:
                     Response_reg; pfam00072"
                     /db_xref="CDD:200976"
     misc_feature    complement(657906..658223)
                     /locus_tag="Smed_4180"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(657936..657941,657948..657950,
                     657999..658001,658059..658061,658083..658085,
                     658212..658217))
                     /locus_tag="Smed_4180"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(658083..658085)
                     /locus_tag="Smed_4180"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(658059..658067,658071..658076))
                     /locus_tag="Smed_4180"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(657933..657941)
                     /locus_tag="Smed_4180"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     gene            661427..661765
                     /locus_tag="Smed_4181"
                     /db_xref="GeneID:5319347"
     CDS             661427..661765
                     /locus_tag="Smed_4181"
                     /note="PFAM: regulatory protein ArsR;
                     KEGG: sme:SMb20608 putative transcriptional regulator,
                     ArsR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein ArsR"
                     /protein_id="YP_001312919.1"
                     /db_xref="GI:150376323"
                     /db_xref="InterPro:IPR001845"
                     /db_xref="GeneID:5319347"
                     /translation="MDPLSSTLSALADPTRRAIIARLAAGEATVNELAAPFDMSLPAV
                     SKHLKVLERAGLISRGRNAQWRPCRLEAAPLKGIADWIERYRDFWTHGFDRLDSYLDE
                     LQRNEKSDHE"
     misc_feature    661448..661687
                     /locus_tag="Smed_4181"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cd00090"
                     /db_xref="CDD:238042"
     misc_feature    order(661448..661453,661457..661459,661466..661468,
                     661475..661480,661487..661492,661499..661501,
                     661589..661591,661655..661660,661664..661672,
                     661676..661684)
                     /locus_tag="Smed_4181"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    order(661451..661456,661466..661474,661511..661519,
                     661544..661555,661559..661564,661571..661576,
                     661580..661585,661601..661609,661622..661624,
                     661631..661636)
                     /locus_tag="Smed_4181"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238042"
     misc_feature    order(661511..661513,661520..661522,661655..661657)
                     /locus_tag="Smed_4181"
                     /note="putative Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238042"
     gene            661797..662261
                     /locus_tag="Smed_4182"
                     /db_xref="GeneID:5319348"
     CDS             661797..662261
                     /locus_tag="Smed_4182"
                     /note="PFAM: Activator of Hsp90 ATPase 1 family protein;
                     KEGG: sme:SMb20607 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="activator of Hsp90 ATPase 1 family protein"
                     /protein_id="YP_001312920.1"
                     /db_xref="GI:150376324"
                     /db_xref="InterPro:IPR013538"
                     /db_xref="GeneID:5319348"
                     /translation="MNASSLKEENALTITRVVNAPRDLVFKVWTTQEHLSRWWGPKDF
                     TVAAMTTDFRRGGAWRCCIRAPEGQDYWAHGIYREIEQPNRIVFSFAWEEEGAIDTLI
                     TVTFEDVSGGTALTFHQTPFTSVESRDSHAEGWSECIDRLADYVAARKEEVQ"
     misc_feature    661830..662240
                     /locus_tag="Smed_4182"
                     /note="Putative hydrophobic ligand-binding SRPBCC domain
                     of Micromonospora echinospora CalC, human Aha1, and
                     related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814"
                     /db_xref="CDD:176856"
     misc_feature    order(661830..661832,661836..661838,661842..661844,
                     661869..661877,661881..661886,661899..661901,
                     661941..661943,661965..661967,661971..661973,
                     661977..661979,661983..661985,662010..662012,
                     662016..662021,662025..662027,662034..662036,
                     662052..662054,662058..662063,662097..662102,
                     662106..662108,662112..662114,662142..662144,
                     662148..662150,662154..662156,662160..662162,
                     662175..662201,662205..662213,662220..662222)
                     /locus_tag="Smed_4182"
                     /note="putative hydrophobic ligand binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:176856"
     gene            662258..662707
                     /locus_tag="Smed_4183"
                     /db_xref="GeneID:5319349"
     CDS             662258..662707
                     /locus_tag="Smed_4183"
                     /note="PFAM: glutathione-dependent formaldehyde-activating
                     GFA;
                     KEGG: sme:SMb20606 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde-activating
                     protein"
                     /protein_id="YP_001312921.1"
                     /db_xref="GI:150376325"
                     /db_xref="InterPro:IPR006913"
                     /db_xref="GeneID:5319349"
                     /translation="MKKAYHGSCHCGAVRFSANLDLAPEGKRSTAPRPGVWWTTTFRC
                     NCSSCLKTRFWKVFVTPEDFSLLSGEEALAEYRFGERMIRHVFCRHCGVHPFASADFE
                     ILGGPFHAVNITCLDDATDEELASAPVVYEDGRHDAWDRSPAVTGYL"
     misc_feature    662264..662695
                     /locus_tag="Smed_4183"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3791"
                     /db_xref="CDD:226314"
     gene            662918..664210
                     /locus_tag="Smed_4184"
                     /db_xref="GeneID:5319350"
     CDS             662918..664210
                     /locus_tag="Smed_4184"
                     /note="KEGG: sme:SMb20605 putative ureashort-chain amide
                     or branched-chain amino acid uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter periplasmic solute-binding
                     protein"
                     /protein_id="YP_001312922.1"
                     /db_xref="GI:150376326"
                     /db_xref="GeneID:5319350"
                     /translation="MTIRARVTGAFLAAVLSTTAFNGAFAAEDTIKVGILHSLSGTMA
                     ISETTLKDAMLMLIEEQNKKGGVLGKKLEAVVVDPASDWPLFAEKARELVSVNKVSAV
                     FGCWTSVSRKSVLPVFEELNSILFYPVQYEGEESQRNVFYTGAAPNQQAIPAVDYLME
                     NEEVERWVLAGTDYVYPRTTNKILEAYLISKGVKPEDIMINYTPFGHSDWQTIVSDIK
                     KFGSAGKKTAVVSTINGDANVPFYKELANQGVKAEDIPVVAFSVGEEELAGLDTGPLV
                     GHLAAWNYFQSVDSPANAAFIETWKAYTKNDKRVTNDPMEAHYIGFNMWLKAVEKAGT
                     TDTDAVLDAMIGVSVPNLSGGYSTMMPNHHITKPVLIGEIQSDGQFETVWETPGLVLG
                     DEWSDYLPDSKDLISDWRAPMSCGNFNVATGKCGGKGS"
     sig_peptide     662918..662998
                     /locus_tag="Smed_4184"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.996 at
                     residue 27"
     misc_feature    663005..664054
                     /locus_tag="Smed_4184"
                     /note="Periplasmic binding protein; Region: Peripla_BP_6;
                     pfam13458"
                     /db_xref="CDD:222144"
     misc_feature    663011..664075
                     /locus_tag="Smed_4184"
                     /note="Periplasmic component (FmdD) of an active transport
                     system for short-chain amides and urea (FmdDEF); Region:
                     PBP1_FmdD_like; cd06355"
                     /db_xref="CDD:107350"
     misc_feature    order(663233..663235,663296..663298,663305..663310,
                     663437..663439)
                     /locus_tag="Smed_4184"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107350"
     gene            664348..665961
                     /locus_tag="Smed_4185"
                     /db_xref="GeneID:5319351"
     CDS             664348..665961
                     /locus_tag="Smed_4185"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20604 putative ureashort-chain amide or
                     branched-chain amino acid uptake ABC transporter permease
                     protein, possibly fusion protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="YP_001312923.1"
                     /db_xref="GI:150376327"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5319351"
                     /translation="MYRIIQTVLAMLFLFAAMPQGLRAAEGLRNLVNALGEAKLSAMD
                     EHIAALAKTGEPEVVAILDALGAGNLYARKTDGQVFLTKESGSNLALIDPISGESAGE
                     TPKAAMSKIKVNNSVRRAVRAALGGLTLLSPDRAQRLKAAQSVLQTPDVDALDAVENA
                     LVAEKDEAVRTVLEQARAAMLLASDRPIEEKKEAVRLLRENGGREALPVLSAALGSAE
                     NGLEQDIEAAIASIEQAQEFWNAGQNVWYGLSLGSVLLLAAIGLAITFGVMGIINMAH
                     GEMVMLGAYTTFLVQDVVRTSFPHLFEWSLAIALPLAFLFTGTVGLVLERGVIRFLYG
                     RPLETLLATWGISLILQQSVRTIFGPTNREVGNPFWMSGAFELGGLTITWNRLWIIVF
                     ALAVFAALLFLLKKTPMGLQMRAVTQNRRMASSMGIRTPLVDALTFALGSGIAGIAGV
                     ALSQIDNVSPNLGQGYIIDSFMVVVFGGVGNLWGTLVGAFSLGILNKFLEPYAGAVLG
                     KILVLVLIILFIQKRPRGLFALKGRAVEA"
     sig_peptide     664348..664422
                     /locus_tag="Smed_4185"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.998 at
                     residue 25"
     misc_feature    665140..665931
                     /locus_tag="Smed_4185"
                     /note="Transmembrane subunit (TM) of Escherichia coli LivH
                     and related proteins. LivH is one of two TMs of the E.
                     coli LIV-1/LS transporter, a Periplasmic Binding Protein
                     (PBP)-dependent ATP-Binding Cassette (ABC) transporter
                     involved in the uptake of...; Region: TM_PBP1_LivH_like;
                     cd06582"
                     /db_xref="CDD:119324"
     misc_feature    665155..665862
                     /locus_tag="Smed_4185"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    665608..665664
                     /locus_tag="Smed_4185"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119324"
     gene            665958..667124
                     /locus_tag="Smed_4186"
                     /db_xref="GeneID:5319352"
     CDS             665958..667124
                     /locus_tag="Smed_4186"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20603 putative ureashort-chain amide or
                     branched-chain amino acid uptake ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="YP_001312924.1"
                     /db_xref="GI:150376328"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5319352"
                     /translation="MITSFLVKSLDRTIAVAVAILLLLAVIVPALNLLTAPDHPLHVP
                     TYMVSLFGKYLTYALLALALDLVWGFCGILSLGHAAFFALGGYAMGMYLMRQIGARGS
                     YGNPLLPDFMVFLNWKELPWFWYGFDMFWFAALMVILVPGLVAFVFGWFAFRSRVNGV
                     YLSIITQAMTYALLLAFFRNDMGFGGNNGLTDFKDILGFNIQADGTRAALFAASALAL
                     AGSLVVTSGIVGSKFGKVLVALRDAESRTRFLGYRVEHMKLFAFTVSAMMAGIAGALY
                     VPQVGIINPGEFAPANSIEVVIWTAVGGRGTLIGPIVGAILVNGGKSIFTAAFPEFWL
                     FALGGLFVLVTLFLPKGVVGTAQHHLARRRQARAAARKEDEQTDLEDAKPMAAE"
     sig_peptide     665958..666065
                     /locus_tag="Smed_4186"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.978) with cleavage site probability 0.784 at
                     residue 36"
     misc_feature    666075..666947
                     /locus_tag="Smed_4186"
                     /note="ABC-type branched-chain amino acid transport
                     system, permease component [Amino acid transport and
                     metabolism]; Region: LivM; COG4177"
                     /db_xref="CDD:226645"
     misc_feature    666117..667019
                     /locus_tag="Smed_4186"
                     /note="Transmembrane subunit (TM) of Escherichia coli LivM
                     and related proteins. LivM is one of two TMs of the E.
                     coli LIV-1/LS transporter, a Periplasmic Binding Protein
                     (PBP)-dependent ATP-Binding Cassette (ABC) transporter
                     involved in the uptake of...; Region: TM_PBP1_LivM_like;
                     cd06581"
                     /db_xref="CDD:119323"
     misc_feature    666690..666746
                     /locus_tag="Smed_4186"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119323"
     gene            667130..667882
                     /locus_tag="Smed_4187"
                     /db_xref="GeneID:5319353"
     CDS             667130..667882
                     /locus_tag="Smed_4187"
                     /note="PFAM: ABC transporter related;
                     KEGG: sme:SMb20602 putative ureashort-chain amide or
                     branched-chain amino acid uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312925.1"
                     /db_xref="GI:150376329"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="GeneID:5319353"
                     /translation="MTEKNPRTLLYLDGVSVSFDGFKALNSLSFVVEPGELRAIIGPN
                     GAGKTTMMDIITGKTRPDEGEVFFKGDIDLTKRDEAEIAQLGIGRKFQKPTVFENHTV
                     WDNLELALNRGRGVFATLFYRLTGEDKRRIEEILATVRLTARRDDLAAGLSHGQKQWL
                     EIGMLLAQEPELLLVDEPVAGMTDAETAETAILLKDIAKTRSVVVVEHDMGFIRDLGV
                     KVTCLAEGSVLAEGSIDFVSNDPKVIENYLGR"
     misc_feature    667151..667879
                     /locus_tag="Smed_4187"
                     /note="urea ABC transporter, ATP-binding protein UrtD;
                     Region: urea_trans_UrtD; TIGR03411"
                     /db_xref="CDD:234200"
     misc_feature    667157..667858
                     /locus_tag="Smed_4187"
                     /note="ATP-binding cassette component of branched chain
                     amino acids transport system; Region:
                     ABC_Mj1267_LivG_branched; cd03219"
                     /db_xref="CDD:213186"
     misc_feature    667253..667276
                     /locus_tag="Smed_4187"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213186"
     misc_feature    order(667262..667267,667271..667279,667403..667405,
                     667655..667660,667751..667753)
                     /locus_tag="Smed_4187"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213186"
     misc_feature    667394..667405
                     /locus_tag="Smed_4187"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213186"
     misc_feature    667583..667612
                     /locus_tag="Smed_4187"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213186"
     misc_feature    667643..667660
                     /locus_tag="Smed_4187"
                     /note="Walker B; other site"
                     /db_xref="CDD:213186"
     misc_feature    667667..667678
                     /locus_tag="Smed_4187"
                     /note="D-loop; other site"
                     /db_xref="CDD:213186"
     misc_feature    667739..667759
                     /locus_tag="Smed_4187"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213186"
     gene            667901..668596
                     /locus_tag="Smed_4188"
                     /db_xref="GeneID:5319354"
     CDS             667901..668596
                     /locus_tag="Smed_4188"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21707 putative ureashort-chain amide or
                     branched-chain amino acid uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312926.1"
                     /db_xref="GI:150376330"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319354"
                     /translation="MLSVENVDLHYGAAQALRNVTFKAEMGKITCVLGRNGVGKSSLL
                     RAITGQHPVTSGTISFNGTPLDGLAPFRRAKHGVGYVPQGREIFPLLTVKENLQTGYA
                     PLKRADRSIPDDIFSLFPVLQTMLGRRGGDLSGGQQQQLAIARALVTRPRILVLDEPT
                     EGIQPSIIKDIGRAIRYLRDSTGMAILLVEQYLDFCRELADHVYIMDRGAFVHEGAPE
                     TLDTPQARRHLTV"
     misc_feature    667904..668593
                     /locus_tag="Smed_4188"
                     /note="urea ABC transporter, ATP-binding protein UrtE;
                     Region: urea_trans_UrtE; TIGR03410"
                     /db_xref="CDD:234199"
     misc_feature    667904..668563
                     /locus_tag="Smed_4188"
                     /note="ATP-binding cassette domain of branched-chain amino
                     acid transporter; Region: ABC_TM1139_LivF_branched;
                     cd03224"
                     /db_xref="CDD:213191"
     misc_feature    668000..668023
                     /locus_tag="Smed_4188"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213191"
     misc_feature    order(668009..668014,668018..668026,668147..668149,
                     668369..668374,668471..668473)
                     /locus_tag="Smed_4188"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213191"
     misc_feature    668138..668149
                     /locus_tag="Smed_4188"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213191"
     misc_feature    668297..668326
                     /locus_tag="Smed_4188"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213191"
     misc_feature    668357..668374
                     /locus_tag="Smed_4188"
                     /note="Walker B; other site"
                     /db_xref="CDD:213191"
     misc_feature    668381..668392
                     /locus_tag="Smed_4188"
                     /note="D-loop; other site"
                     /db_xref="CDD:213191"
     misc_feature    668459..668479
                     /locus_tag="Smed_4188"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213191"
     gene            668964..669359
                     /locus_tag="Smed_4189"
                     /db_xref="GeneID:5318947"
     CDS             668964..669359
                     /locus_tag="Smed_4189"
                     /note="KEGG: sme:SMb20600 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312927.1"
                     /db_xref="GI:150376331"
                     /db_xref="GeneID:5318947"
                     /translation="MTNFLPALYQGHAPITLQTLFKDALEAYDDWEEGMPEPIVSFEG
                     KVLPVSAVFQWMRPCTDLMPANMIVIVADRLTKPWSGAGPMDAMTFSTAARVMSVLVR
                     RRLKRFGRGSIEAFAERFSQPMHAAAHEG"
     gene            complement(669451..670527)
                     /locus_tag="Smed_4190"
                     /db_xref="GeneID:5318948"
     CDS             complement(669451..670527)
                     /locus_tag="Smed_4190"
                     /note="TIGRFAM: parB-like partition protein;
                     PFAM: ParB domain protein nuclease; RepB plasmid
                     partition;
                     KEGG: sme:SMb20599 putative smb01f11-replication protein"
                     /codon_start=1
                     /transl_table=11
                     /product="parB-like partition protein"
                     /protein_id="YP_001312928.1"
                     /db_xref="GI:150376332"
                     /db_xref="InterPro:IPR003115"
                     /db_xref="InterPro:IPR004437"
                     /db_xref="InterPro:IPR011111"
                     /db_xref="GeneID:5318948"
                     /translation="MAGNNRKNELRALFSGSAPAANQQAPADAMQGELTPVNARPTAA
                     RDVPDPAKARAASGAVKAMGLSLGSITREAEEARVLREALNQGERIVSLDPALVAASF
                     IEDRLTNGEVDDPDFLALVESIRENGQQSPILVRPHPERQGHYQTAYGHRRLKAVRRL
                     ELQVKAIVRPLTDDELVLAQGKENAERRNLSFIERALFAAALAVRGFDRKVIGDALAV
                     QKSELSRLLQVAEGVPHEIARAIGPAPKVGRERWMAIGGLLIREEARARAKDEIASPR
                     FRAAETDQRFQLVFNCVSERDKPEPERPEDLLDAAGQPFARLRRDGKTPRIEFLPGTH
                     PAFVQEAVAMLARWHAAFVEKQRN"
     misc_feature    complement(669466..670410)
                     /locus_tag="Smed_4190"
                     /note="plasmid partitioning protein RepB; Provisional;
                     Region: PRK13866"
                     /db_xref="CDD:172387"
     misc_feature    complement(669976..670191)
                     /locus_tag="Smed_4190"
                     /note="ParB-like nuclease domain; Region: ParBc;
                     pfam02195"
                     /db_xref="CDD:216926"
     gene            complement(670531..671793)
                     /locus_tag="Smed_4191"
                     /db_xref="GeneID:5318949"
     CDS             complement(670531..671793)
                     /locus_tag="Smed_4191"
                     /note="PFAM: regulatory protein MerR; Cobyrinic acid
                     ac-diamide synthase;
                     KEGG: sme:SMb20598 probable replication protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinic acid ac-diamide synthase"
                     /protein_id="YP_001312929.1"
                     /db_xref="GI:150376333"
                     /db_xref="InterPro:IPR000551"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="GeneID:5318949"
                     /translation="MNMKVSAAQTTAAGGAAFGRPADEAIAADARALSEQLKAMRDRL
                     FPPTARKTLRSFTSGEAAKLIGVSDGYLRQLSLAGEGPQPDTGAGGRRSYSLCDINAL
                     RRHLAEQAVSKGNGAKARGYLKWRDALRSEHLQVISVTNFKGGSGKTTSSVHLAQYLA
                     LTGHRVLAVDLDPQASLSALFGYQPELDLTGNDTLYGAIRYDAEARPLKEIIRKTYFD
                     GLDLVPGNLELQEFEHTTPQALSARQSGADAGPLFFARVQAALASVADDYDVVVIDCP
                     PQLGYLTLSALCASTSVIVTVHPQMLDVASMNQFLYMTSDLLSVVREAGGELNFDFLR
                     YLVTRFEPNDGPQAQIVGFMRSLFGERVLTSAMVKSTAISDAGLTKQTLYEVGRENFT
                     RATYDRAIESLNAVNGEIEALIHAAWGR"
     sig_peptide     complement(671734..671793)
                     /locus_tag="Smed_4191"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.884) with cleavage site probability 0.806 at
                     residue 20"
     misc_feature    complement(670534..671697)
                     /locus_tag="Smed_4191"
                     /note="plasmid partitioning protein RepA; Region:
                     partition_RepA; TIGR03453"
                     /db_xref="CDD:234215"
     misc_feature    complement(671512..671625)
                     /locus_tag="Smed_4191"
                     /note="MerR family regulatory protein; Region: MerR;
                     pfam00376"
                     /db_xref="CDD:201190"
     misc_feature    complement(<671272..671388)
                     /locus_tag="Smed_4191"
                     /note="ParA and ParB of Caulobacter crescentus belong to a
                     conserved family of bacterial proteins implicated in
                     chromosome segregation. ParB binds to DNA sequences
                     adjacent to the origin of replication and localizes to
                     opposite cell poles shortly following the...; Region:
                     ParA; cd02042"
                     /db_xref="CDD:238997"
     misc_feature    complement(671347..671367)
                     /locus_tag="Smed_4191"
                     /note="P-loop; other site"
                     /db_xref="CDD:238997"
     misc_feature    complement(671347..671349)
                     /locus_tag="Smed_4191"
                     /note="Magnesium ion binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238997"
     misc_feature    complement(<670963..671343)
                     /locus_tag="Smed_4191"
                     /note="transport-energizing ATPase, TRC40/GET3/ArsA
                     family; Region: GET3_arsA_TRC40; TIGR00345"
                     /db_xref="CDD:232932"
     misc_feature    complement(670780..>670992)
                     /locus_tag="Smed_4191"
                     /note="ParA and ParB of Caulobacter crescentus belong to a
                     conserved family of bacterial proteins implicated in
                     chromosome segregation. ParB binds to DNA sequences
                     adjacent to the origin of replication and localizes to
                     opposite cell poles shortly following the...; Region:
                     ParA; cd02042"
                     /db_xref="CDD:238997"
     misc_feature    complement(670972..670974)
                     /locus_tag="Smed_4191"
                     /note="Magnesium ion binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238997"
     gene            complement(672152..672814)
                     /locus_tag="Smed_4192"
                     /db_xref="GeneID:5318950"
     CDS             complement(672152..672814)
                     /locus_tag="Smed_4192"
                     /note="PFAM: ErfK/YbiS/YcfS/YnhG family protein;
                     KEGG: atc:AGR_L_2979 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ErfK/YbiS/YcfS/YnhG family protein"
                     /protein_id="YP_001312930.1"
                     /db_xref="GI:150376334"
                     /db_xref="InterPro:IPR005490"
                     /db_xref="GeneID:5318950"
                     /translation="MLGGCSTSSARNAEPAPPLVDNSIYASVYGPKPDELFPLPAIPY
                     EKIDPRFYRQMVANPTGERPGVLVVDTANHFLYLTYEAGQAMRYGVGLGRQGFEWAGR
                     GVIQYKRQWPRWTPPDEMVARQPELEPYSIANGGMEPGLTNPLGARALYIFQNGVDTL
                     YRIHGSPEWWTIGKSVSSGCVRMINQDVVDLYNRVQNGTPVVVTNLGSPLSAPIPPVE
                     GA"
     misc_feature    complement(672200..672793)
                     /locus_tag="Smed_4192"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: ErfK; COG1376"
                     /db_xref="CDD:224294"
     misc_feature    complement(672206..672625)
                     /locus_tag="Smed_4192"
                     /note="L,D-transpeptidase catalytic domain; Region: YkuD;
                     pfam03734"
                     /db_xref="CDD:217702"
     gene            complement(672893..673987)
                     /locus_tag="Smed_4193"
                     /db_xref="GeneID:5318951"
     CDS             complement(672893..673987)
                     /locus_tag="Smed_4193"
                     /note="PFAM: protein of unknown function DUF949;
                     KEGG: atc:AGR_L_2977 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312931.1"
                     /db_xref="GI:150376335"
                     /db_xref="InterPro:IPR010355"
                     /db_xref="GeneID:5318951"
                     /translation="MVFSGERTEPRGFSLLRISFQKMRITPVTIVRMAKIGLALSAAA
                     FLSGCLAMGLYDLSKAPPQLSKKVLAEMAKKKMSPNSPVLVRIFKKESELEVWKADAS
                     GTYALFKTYPMCRWSGKLGPKKKDGDRQAPEGFYHVSARMLNPNSQYYVSFNLGYPNR
                     LESALGYTGEALMVHGACSSAGCYAMTDRGVGEIYAIVQRALAAGQKHFQVQAYPFRM
                     TTENMALHKGDPSMAFWKTLKQGYDAFAFSRRQPKVSVCGGRYVFNTEFEGGEPRDPL
                     AACPSAMSTADTELLARIEAEGHRVETAIASSGTTPIFAYVDGGMHPTFRTMLEKVGP
                     DRLAAAISATKYPVSRPQAALADPYAGSSN"
     misc_feature    complement(673136..673834)
                     /locus_tag="Smed_4193"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3034"
                     /db_xref="CDD:225577"
     gene            674323..677178
                     /locus_tag="Smed_4194"
                     /db_xref="GeneID:5318952"
     CDS             674323..677178
                     /locus_tag="Smed_4194"
                     /note="PFAM: cell divisionFtsK/SpoIIIE;
                     KEGG: sme:SMb20595 putative cell division protein FtsK
                     like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="YP_001312932.1"
                     /db_xref="GI:150376336"
                     /db_xref="InterPro:IPR002543"
                     /db_xref="GeneID:5318952"
                     /translation="MRIPRTNFSTAALYDANQAEDFEDPQPVVPGIVHASAPESAAHD
                     HLFEAPEAPRRASGYRQEEISQATRAVRLYGHGSAYAPAEVTVSTRDPLPTLAEITGL
                     SCEPGWESHFFLSPNVRFTRTPEREFMKRRPPVPEDNEVDVAEAAAEAPLAETVTGKE
                     PVEPLPSPAETDAPSYSPSELLRVLVQQLPSFNAAHLQTPEKNAVEQAAEAAVLTEEE
                     PSIPQAPHVPIMEEAPVVADASTGTAAVPDSAGAEDVARQAEARLSYLSDFAFFEFMP
                     LEPPVALRTVAAPAEESAHVAAPSSALPKAAAPNIVSAPVRIPSQPPAAITSLFRVVE
                     CRRPEAGPDVSAPDAPQDLGAEPISAGAAVGAEAVEAQGLTPEAPDEPAREPAPEAAV
                     VPAKEPAPEAPVTRAAITMPAVIQRSSPALPPVGATERPGIADAYEFPSKELLQEPPQ
                     GQGFFMTQEQLEQNAGLLESVLEDFGVKGEIIHVRPGPVVTLYEFEPAPGVKSSRVIG
                     LADDIARSMSALSARVAVVPGRNVIGIELPNATRETVYFRELIESGDFQKTGCKLALC
                     LGKTIGGEPVIAELAKMPHLLVAGTTGSGKSVAINTMILSLLYRLKPEECRLIMVDPK
                     MLELSVYDGIPHLLTPVVTDPKKAVMALKWAVREMEDRYRKMSRLGVRNIDGYNQRAA
                     AAREKGEPILATVQTGFEKGTGEPLFEQQEMDLSPMPYIVVIVDEMADLMMVAGKEIE
                     GAIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQ
                     GAEQLLGQGDMLHMAGGGRIARVHGPFVSDQEVEHVVAHLKTQGRPEYLETVTADEEE
                     EEPEEDQGAVFDKSAIAAEDGNELYDQAVKVVLRDKKCSTSYIQRRLGIGYNRAASLV
                     ERMEKDGLVGPANHVGKREIIYGNRDGGPKPDSDELD"
     misc_feature    <675538..677139
                     /locus_tag="Smed_4194"
                     /note="DNA segregation ATPase FtsK/SpoIIIE and related
                     proteins [Cell division and chromosome partitioning];
                     Region: FtsK; COG1674"
                     /db_xref="CDD:224588"
     misc_feature    675958..676620
                     /locus_tag="Smed_4194"
                     /note="FtsK/SpoIIIE family; Region: FtsK_SpoIIIE;
                     pfam01580"
                     /db_xref="CDD:216584"
     misc_feature    676945..677127
                     /locus_tag="Smed_4194"
                     /note="Ftsk gamma domain; Region: Ftsk_gamma; pfam09397"
                     /db_xref="CDD:220220"
     gene            complement(677285..677602)
                     /locus_tag="Smed_4195"
                     /db_xref="GeneID:5318953"
     CDS             complement(677285..677602)
                     /locus_tag="Smed_4195"
                     /note="PFAM: blue (type 1) copper domain protein;
                     KEGG: sme:SMb20594 putative amicyanin precursor protein"
                     /codon_start=1
                     /transl_table=11
                     /product="blue (type1) copper domain-containing protein"
                     /protein_id="YP_001312933.1"
                     /db_xref="GI:150376337"
                     /db_xref="InterPro:IPR000923"
                     /db_xref="InterPro:IPR011572"
                     /db_xref="GeneID:5318953"
                     /translation="MFASRAAIVLLSVGAAGIAAPSQAETILVAIDRLVYSPAEVDAR
                     VGDEIEWINKDVLVHTATVKGGAEVLLPAKKSGRLVLKEAGSFDYTCRYHPNMKGRVT
                     VRP"
     sig_peptide     complement(677528..677602)
                     /locus_tag="Smed_4195"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 25"
     misc_feature    complement(677288..677587)
                     /locus_tag="Smed_4195"
                     /note="Plastocyanin [Energy production and conversion];
                     Region: PetE; COG3794"
                     /db_xref="CDD:226317"
     misc_feature    complement(677294..677587)
                     /locus_tag="Smed_4195"
                     /note="Cupredoxin-like domain; Region: Cupredoxin_1;
                     cl17234"
                     /db_xref="CDD:247788"
     gene            complement(677611..678135)
                     /locus_tag="Smed_4196"
                     /db_xref="GeneID:5318954"
     CDS             complement(677611..678135)
                     /locus_tag="Smed_4196"
                     /note="KEGG: sme:SMb20593 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312934.1"
                     /db_xref="GI:150376338"
                     /db_xref="GeneID:5318954"
                     /translation="MTIRLTTAATAIALLIGASGALGNDKPTDPQIAHIAYTAGLLDI
                     EAAKQAIATSKNKTVVEFAESMLRDHETVNTQALDLVKKLNVTPEDNDTSKSLSQAAE
                     SKRQELAKLEGAAFDKAYIEQEVAYHKQVNGALETLLIPSAQNAELKSLLETGLKLFR
                     GHQQHAEHVAAELK"
     sig_peptide     complement(678064..678135)
                     /locus_tag="Smed_4196"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.991 at
                     residue 24"
     misc_feature    complement(677614..678066)
                     /locus_tag="Smed_4196"
                     /note="Predicted outer membrane protein [Function
                     unknown]; Region: COG3652"
                     /db_xref="CDD:226178"
     gene            complement(678214..678885)
                     /locus_tag="Smed_4197"
                     /db_xref="GeneID:5318955"
     CDS             complement(678214..678885)
                     /locus_tag="Smed_4197"
                     /note="member of the extracytoplasmic function sigma
                     factors which are active under specific conditions; binds
                     with the catalytic core of RNA polymerase to produce the
                     holoenzyme and directs bacterial core RNA polymerase to
                     specific promoter elements to initiate transcription"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="YP_001312935.1"
                     /db_xref="GI:150376339"
                     /db_xref="InterPro:IPR000838"
                     /db_xref="InterPro:IPR007627"
                     /db_xref="InterPro:IPR007630"
                     /db_xref="InterPro:IPR013249"
                     /db_xref="InterPro:IPR014284"
                     /db_xref="GeneID:5318955"
                     /translation="MPVTEIDLCLNASPPAQDLARLRAIMQAHNRKLYRIARSILRND
                     SDAEDVLQEAYVRAFTRFQDFRGDAAITTWLARIVINEALGRLRKRRRQMKLASDMRQ
                     SQEAEIIAFPLNSGISDPEKTMAQRQILDLVERLTDDLPDAYRTVFVLRVIEGLSNEE
                     TTALLGLKPETARTRLHRARRLLKEQLERQIGPVLLDAFPFAGMRCERLTEAVLARLA
                     EIPMK"
     misc_feature    complement(678223..678885)
                     /locus_tag="Smed_4197"
                     /note="RNA polymerase sigma factor; Provisional; Region:
                     PRK11922"
                     /db_xref="CDD:237024"
     misc_feature    complement(678607..678813)
                     /locus_tag="Smed_4197"
                     /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542"
                     /db_xref="CDD:218138"
     misc_feature    complement(<678376..678498)
                     /locus_tag="Smed_4197"
                     /note="Sigma70, region (SR) 4 refers to the most
                     C-terminal of four conserved domains found in Escherichia
                     coli (Ec) sigma70, the main housekeeping sigma, and
                     related sigma-factors (SFs). A SF is a dissociable subunit
                     of RNA polymerase, it directs bacterial or...; Region:
                     Sigma70_r4; cl17257"
                     /db_xref="CDD:247811"
     gene            679315..679599
                     /locus_tag="Smed_4198"
                     /db_xref="GeneID:5318956"
     CDS             679315..679599
                     /locus_tag="Smed_4198"
                     /note="catalyzes the hydrolysis of acylphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="YP_001312936.1"
                     /db_xref="GI:150376340"
                     /db_xref="InterPro:IPR001792"
                     /db_xref="GeneID:5318956"
                     /translation="MTKDRRAALVRITGRVQGVCFRDWTREEAEKLGLDGWVRNESDG
                     SVTALIAGPDGAVSRMLENFWKGPPGASIADVASEVASSVEAPAGFRITR"
     misc_feature    679315..679596
                     /locus_tag="Smed_4198"
                     /note="acylphosphatase; Provisional; Region: PRK14425"
                     /db_xref="CDD:172901"
     gene            complement(679796..681556)
                     /locus_tag="Smed_4199"
                     /db_xref="GeneID:5319094"
     CDS             complement(679796..681556)
                     /locus_tag="Smed_4199"
                     /EC_number="2.3.2.2"
                     /note="TIGRFAM: gamma-glutamyltransferase;
                     PFAM: gamma-glutamyltranspeptidase;
                     KEGG: sme:SMb20585 putative gamma-glutamyltranspeptidase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="YP_001312937.1"
                     /db_xref="GI:150376341"
                     /db_xref="InterPro:IPR000101"
                     /db_xref="GeneID:5319094"
                     /translation="MPNSCLKSGPRLKSVSIILMLALCAFVPQGQAASPEPVKADHGM
                     VVTAQHLASDIGVEVLRKGGNAIDAAVAVGYALAVVYPTAGNIGGGGFMTIRFKDGKT
                     TFLDFRERAPIGATKTMYLDDQGNLVEGLSTEGYLAVGVPGPVMGFELARNRYGTRPL
                     NELIEPAIKLAREGFVLEQGDIDSFDGENERLARDPAAAAIFLKPDGKPFAVGDRLVQ
                     TDLAASLASIAEKGTDAFYRGPIADAIVKASTDKGGILAKQDFERYQVRELEPVRCNY
                     RGYEIVSSPPPSSGGVIICEILNILEGYPLSYLGYGSAETVHAMIEAMRHAYVDRNTA
                     LGDPAFVENPVAKLVDKAYAKEIRAKIDPFKAGVSEALMPAGFTESKETTHYSIVDDE
                     GNAVAVTYTLNGSFGAGVVAPGTGILLNNEMDDFTAKPGAPNLYGLVQGEANAIEPGK
                     TPLSSMSPTIISKDGKPLMVIGSPGGARIITITLEAILNVIDHGMTIQEAVDAPRIHH
                     QWLPDKVFMEPYALSPDTRKLLSSMGHDVEIDENWTIWGQAAGILVGGENIAEIEAGG
                     GARYNGALDSRIGAGAARGY"
     sig_peptide     complement(681458..681556)
                     /locus_tag="Smed_4199"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.974 at
                     residue 33"
     misc_feature    complement(679799..681475)
                     /locus_tag="Smed_4199"
                     /note="Gamma-glutamyltransferase [Amino acid transport and
                     metabolism]; Region: Ggt; COG0405"
                     /db_xref="CDD:223482"
     misc_feature    complement(679895..681388)
                     /locus_tag="Smed_4199"
                     /note="Gamma-glutamyltranspeptidase; Region:
                     G_glu_transpept; pfam01019"
                     /db_xref="CDD:216247"
     gene            complement(681667..682329)
                     /locus_tag="Smed_4200"
                     /db_xref="GeneID:5319095"
     CDS             complement(681667..682329)
                     /locus_tag="Smed_4200"
                     /note="PFAM: oxidoreductase molybdopterin binding;
                     KEGG: sme:SMb20584 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin binding oxidoreductase"
                     /protein_id="YP_001312938.1"
                     /db_xref="GI:150376342"
                     /db_xref="InterPro:IPR000572"
                     /db_xref="GeneID:5319095"
                     /translation="MAEATEAPETKLTSTKRRWAADGKFLTGRTARPETDRLPPGQHL
                     VKDWPILDLGQQPHLTHETWRLDITGLVENPLSLDWTAFQALPQTDSQSDIHCVTTWS
                     RYDNRWRGVHTRDLLDRAMPKPEAVYVMLTSYDGYSTNLPLADFAAEDAILATAWEGE
                     PISRAHGGPMRLVVPHLYFWKSAKWLQRIDFRAADFAGFWERNGYHMRGDPWLEERYS
                     GD"
     misc_feature    complement(681670..682326)
                     /locus_tag="Smed_4200"
                     /note="Sulfite oxidase and related enzymes [General
                     function prediction only]; Region: COG2041"
                     /db_xref="CDD:224952"
     misc_feature    complement(681679..682218)
                     /locus_tag="Smed_4200"
                     /note="bacterial and archael members of the sulfite
                     oxidase (SO) family of molybdopterin binding domains. This
                     molybdopterin cofactor (Moco) binding domain is found in a
                     variety of oxidoreductases, main members of this family
                     are nitrate reductase (NR) and...; Region:
                     arch_bact_SO_family_Moco; cd02109"
                     /db_xref="CDD:239027"
     misc_feature    complement(order(681775..681780,681784..681786,
                     681793..681795,681817..681819,681832..681834,
                     681919..681921,682039..682041,682174..682176,
                     682180..682182,682186..682188))
                     /locus_tag="Smed_4200"
                     /note="Moco binding site; other site"
                     /db_xref="CDD:239027"
     misc_feature    complement(682039..682041)
                     /locus_tag="Smed_4200"
                     /note="metal coordination site [ion binding]; other site"
                     /db_xref="CDD:239027"
     gene            complement(682428..683309)
                     /locus_tag="Smed_4201"
                     /db_xref="GeneID:5319096"
     CDS             complement(682428..683309)
                     /locus_tag="Smed_4201"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type;
                     KEGG: rle:RL3904 putative AraC family transcriptional
                     regulator for P-hydroxybenzoate hydroxylase"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="YP_001312939.1"
                     /db_xref="GI:150376343"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="GeneID:5319096"
                     /translation="MKAPVPNYELYGEKSRERPDFWLHCETIHARSSLYRWEIGLHRH
                     ERFFQILYIAGGSGDALFEKTVEQISSPAVITVPPGIGHGFRFSPDVDGFVFTVLASH
                     LPISPGRSSRPGAWMAAPRLTPLGGSEDGRYIGETLRRLATECEAGLSHRTVLLDAYL
                     TTALVLTGRLAEGGDDEGAESENERRMERFDALLRQHYLTHRPAAFYARALGLSPTHF
                     SRIVRAATGRSLHEVIAGKLVEEAKRQLLFTRGSVQQIGFRLGFGDPAYFSRFFLRRT
                     GMTPRAWRTAERERLGA"
     misc_feature    complement(682458..683300)
                     /locus_tag="Smed_4201"
                     /note="4-hydroxyphenylacetate catabolism regulatory
                     protein HpaA; Region: HpaA; TIGR02297"
                     /db_xref="CDD:131350"
     misc_feature    complement(683040..>683198)
                     /locus_tag="Smed_4201"
                     /note="Cupin domain; Region: Cupin_2; cl17218"
                     /db_xref="CDD:247772"
     misc_feature    complement(682455..>682556)
                     /locus_tag="Smed_4201"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     gene            683419..684591
                     /locus_tag="Smed_4202"
                     /db_xref="GeneID:5319097"
     CDS             683419..684591
                     /locus_tag="Smed_4202"
                     /EC_number="1.14.13.2"
                     /note="catalyzes the formation of protocatechuate from
                     4-hydroxybenzoate"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate 3-monooxygenase"
                     /protein_id="YP_001312940.1"
                     /db_xref="GI:150376344"
                     /db_xref="InterPro:IPR002938"
                     /db_xref="InterPro:IPR003042"
                     /db_xref="InterPro:IPR012733"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="GeneID:5319097"
                     /translation="MRTQVVIIGSGPSGLLLGQLLARAGIANVIVDHASKDHILGRVR
                     AGVLEEGTVRLMDEAGSGARMHAEGIAHDGFSLAFDGRDHRIDLFGLTGGRRVMIYGQ
                     MELTRDLMDQRERAGAPSVYEAESVTPRDFEGDAPHVAYRKNGIAHRIDCDFIAGCDG
                     FHGVSRRSVPQNAFRSFEKVYPFGWLGILADVPPVDDELVYANHPRGFALCSMRSHTR
                     SRHYIQCPLGEKIGDWSDQRFWDELRRRLPAHHAERVVTGPSFEKSIAPLRSFVAEPM
                     RFNRLFLAGDAAHIVPPTGAKGLNLAASDVHYLFEAFVEHYQDRSNAGIDAYSARALA
                     RVWKAVRFSWWMTTILHRFPETSEFDQKIQEAELAYLTHSSAAATALAENYVGLPF"
     misc_feature    683419..684588
                     /locus_tag="Smed_4202"
                     /note="4-hydroxybenzoate 3-monooxygenase; Validated;
                     Region: PRK08243"
                     /db_xref="CDD:236198"
     sig_peptide     683419..683493
                     /locus_tag="Smed_4202"
                     /product="4-hydroxybenzoate 3-monooxygenase"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.650) with cleavage site probability 0.518 at
                     residue 25"
     gene            684697..685617
                     /locus_tag="Smed_4203"
                     /db_xref="GeneID:5319098"
     CDS             684697..685617
                     /locus_tag="Smed_4203"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb20582 putative transcriptional regulator,
                     LysR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001312941.1"
                     /db_xref="GI:150376345"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5319098"
                     /translation="MGLTLRQIEVIRAVMIAGTIAGAARLMNVAQPGVSRTMKHIESA
                     LGIKLFVRKAGRYVPTAEARNVFAQLQEVHRKVDDLQFSIGQLERGRGVELALGSVPS
                     IANAMVPQAIATLMRRHPDIRINFDILRIEEAIDYLLLGKGELVAMSYHLSHPSITFE
                     PLSRGHLVCIAAREHPIAERTSISAREIAGHPLIGLDPRDPYGAIIAGIFESEGLEYH
                     TPIRARFGTTVCALVRRNLGIAVVDAFTVGDMTDQGLAVIPIDEETGFQTYVAYRADA
                     VLSSYAERFVKTLRRVMNESVRRSTRLTEL"
     misc_feature    684697..685569
                     /locus_tag="Smed_4203"
                     /note="DNA-binding transcriptional regulator LysR;
                     Provisional; Region: PRK11013"
                     /db_xref="CDD:236819"
     misc_feature    684709..684888
                     /locus_tag="Smed_4203"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    684976..685563
                     /locus_tag="Smed_4203"
                     /note="The C-terminal substrate-domain of LysR-type
                     transcriptional regulators involved in the catabolism of
                     opines and that of related regulators, contains the type 2
                     periplasmic binding fold; Region: PBP2_LysR_opines_like;
                     cd08415"
                     /db_xref="CDD:176107"
     misc_feature    order(685021..685026,685030..685035,685042..685044,
                     685054..685056,685060..685080,685354..685371,
                     685387..685392,685396..685401)
                     /locus_tag="Smed_4203"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176107"
     gene            685750..687639
                     /locus_tag="Smed_4204"
                     /db_xref="GeneID:5319099"
     CDS             685750..687639
                     /locus_tag="Smed_4204"
                     /note="PFAM: Glyoxalase/bleomycin resistance
                     protein/dioxygenase; Xylose isomerase domain protein TIM
                     barrel;
                     KEGG: sme:SMb20581 putative 4-hydroxyphenylpyruvate
                     dioxygenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase domain-containing protein"
                     /protein_id="YP_001312942.1"
                     /db_xref="GI:150376346"
                     /db_xref="InterPro:IPR004360"
                     /db_xref="InterPro:IPR012307"
                     /db_xref="GeneID:5319099"
                     /translation="MKTSIATVSISGTLSEKLAAVAAAGFDGVEIFENDFLTFDGSPA
                     EVGRIVRDHGLKVTLFQPFRDFEGLPEPHRSRAFDRAERKFDVMQELGTELMLVCSSV
                     SPLALGGIDRAADDFRELGERAARRNLRVGYEALAWGRHVNDHRDAWEIVRRADHPNV
                     GLILDSFHTLARNIDLRSIRSIPGDRIFIVQLADAPRIEMDLLYLSRHFRNMPGEGDL
                     PLVDFMSAVAATGYDGAISLEIFNDQFRGGSPQAIAEDGHRSLVYLMDRVRRHEPAAK
                     SAEALPDRVEVLGVEFVEFTADQTEAEALGSLLGAMGFRAVASHREKAVTLWRQGCDH
                     RGINVVINTEQKGFAHSSYLVHGASAYAIGLKVPDASAAVERARALGAEIFLPESGEG
                     EGAMAAIRGMGGGLIYFVDEIDDVWSREFVAPGDDRQPAATLVAIDHVAQSMKEEQLP
                     SWLLFYTSILDADKLAQVDIVDPAGLVRSQVVENASGTLRLTLNGADNHRTLAGHFIA
                     ESFGSGVQHVAFRTDDIFEAAEHMRRSGFRALAISRNYYDDIEVRFALEPGFVDRLRD
                     ENILYDRDEDGEYFQIYGPTFGEGFFFEIVERRSGYRGYGAANAPFRIAAQKRCLRPA
                     GMPAE"
     misc_feature    685750..686478
                     /locus_tag="Smed_4204"
                     /note="Sugar phosphate isomerases/epimerases [Carbohydrate
                     transport and metabolism]; Region: IolE; COG1082"
                     /db_xref="CDD:224007"
     sig_peptide     685750..685812
                     /locus_tag="Smed_4204"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.610) with cleavage site probability 0.510 at
                     residue 21"
     misc_feature    686551..687636
                     /locus_tag="Smed_4204"
                     /note="4-hydroxyphenylpyruvate dioxygenase and related
                     hemolysins [Amino acid transport and metabolism / General
                     function prediction only]; Region: COG3185"
                     /db_xref="CDD:225726"
     misc_feature    686617..686994
                     /locus_tag="Smed_4204"
                     /note="N-terminal domain of 4-hydroxyphenylpyruvate
                     dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS);
                     Region: HPPD_N_like; cd08342"
                     /db_xref="CDD:176690"
     misc_feature    order(686656..686664,686668..686673,686719..686721,
                     686725..686727,686821..686823)
                     /locus_tag="Smed_4204"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:176690"
     misc_feature    687049..687606
                     /locus_tag="Smed_4204"
                     /note="C-terminal domain of 4-hydroxyphenylpyruvate
                     dioxygenase (HppD) and hydroxymandelate Synthase (HmaS);
                     Region: HPPD_C_like; cd07250"
                     /db_xref="CDD:176673"
     misc_feature    order(687064..687066,687184..687186,687223..687225,
                     687229..687231,687253..687255,687298..687300,
                     687496..687498,687529..687531,687562..687564,
                     687574..687579)
                     /locus_tag="Smed_4204"
                     /note="active site"
                     /db_xref="CDD:176673"
     misc_feature    order(687064..687066,687298..687300,687529..687531)
                     /locus_tag="Smed_4204"
                     /note="Fe binding site [ion binding]; other site"
                     /db_xref="CDD:176673"
     gene            complement(687665..688615)
                     /locus_tag="Smed_4205"
                     /db_xref="GeneID:5319100"
     CDS             complement(687665..688615)
                     /locus_tag="Smed_4205"
                     /note="TIGRFAM: pca operon transcription factor PcaQ;
                     PFAM: regulatory protein LysR; LysR substrate-binding;
                     KEGG: sme:SMb20580 putative transcriptional activator of
                     the pca operon, LysR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001312943.1"
                     /db_xref="GI:150376347"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="InterPro:IPR012787"
                     /db_xref="GeneID:5319100"
                     /translation="MRNVIDARVKFRHLLTFVEVARQKSVVKAAELLHVTQPAVTKTI
                     RELEEVLGVAVFEREGRGIKITRYGEVFLRHAGAALTALRQGLDSVSQELSGGGPPIR
                     IGALPTVSTRIMPGAITLFLKEKTGARIKIVTGENAVLLEQLRVGDLDLVVGRLAAPD
                     KMTGFSFEHLYSEQVVFAVRAGHPLLSGKRAVFAHLSDYPVLMPTRASIIRPFVEQFL
                     IANGIAGLPNQIETVSDSFGRAFVRSSDAIWIISAGVVAADIADGMLSALPVDTSETR
                     GPVGLTMRTDSIPSLPLSILMQTLREAAEAAMAADTKKAL"
     misc_feature    complement(687713..688594)
                     /locus_tag="Smed_4205"
                     /note="pca operon transcription factor PcaQ; Region:
                     TF_pcaQ; TIGR02424"
                     /db_xref="CDD:233862"
     misc_feature    complement(688406..688585)
                     /locus_tag="Smed_4205"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    complement(687716..688318)
                     /locus_tag="Smed_4205"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cl11398"
                     /db_xref="CDD:245600"
     misc_feature    complement(order(687884..687889,687893..687898,
                     687914..687931,688214..688234,688238..688240,
                     688250..688252,688259..688264,688268..688273))
                     /locus_tag="Smed_4205"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            688701..689507
                     /locus_tag="Smed_4206"
                     /db_xref="GeneID:5319101"
     CDS             688701..689507
                     /locus_tag="Smed_4206"
                     /note="TIGRFAM: 3-oxoadipate enol-lactonase;
                     PFAM: alpha/beta hydrolase fold; Ndr family protein;
                     KEGG: sme:SMb20579 putative beta-ketoadipate enol-lactone
                     hydrolase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoadipate enol-lactonase"
                     /protein_id="YP_001312944.1"
                     /db_xref="GI:150376348"
                     /db_xref="InterPro:IPR000073"
                     /db_xref="InterPro:IPR000834"
                     /db_xref="InterPro:IPR003089"
                     /db_xref="InterPro:IPR004142"
                     /db_xref="InterPro:IPR012790"
                     /db_xref="GeneID:5319101"
                     /translation="MQFTRINDVTIHYRVVGAVAEKPVLVFINSLGTDFRIWRDLVLR
                     LSGDFAIVLYDKRGHGLSDIGQVPYSIEDHATDLAGLLDRLAVKGAIVCGLSVGGLVA
                     QSLCVRRPDLVHALVLSDTAHKIGTTEFWDARIAAIEAHGIEAIADGILERWFTAAFR
                     RPENTAFAGYRNMLVRQPVPGYIGTCAAIRDADFTQAAGKIAVPVLCVVGEEDGSTPP
                     DLVRSTAQLIPGASFEVICGAGHIPCVEQPEALTSVLRRFFRTVLPGENP"
     misc_feature    688722..688949
                     /locus_tag="Smed_4206"
                     /note="Putative lysophospholipase; Region: Hydrolase_4;
                     pfam12146"
                     /db_xref="CDD:221442"
     misc_feature    688728..689480
                     /locus_tag="Smed_4206"
                     /note="3-oxoadipate enol-lactonase; Region: protocat_pcaD;
                     TIGR02427"
                     /db_xref="CDD:131480"
     gene            689504..689911
                     /locus_tag="Smed_4207"
                     /db_xref="GeneID:5319102"
     CDS             689504..689911
                     /locus_tag="Smed_4207"
                     /EC_number="4.1.1.44"
                     /note="TIGRFAM: 4-carboxymuconolactone decarboxylase;
                     PFAM: Carboxymuconolactone decarboxylase;
                     KEGG: sme:SMb20578 putative gamma carboxymuconolactone
                     decarboxylase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="4-carboxymuconolactone decarboxylase"
                     /protein_id="YP_001312945.1"
                     /db_xref="GI:150376349"
                     /db_xref="InterPro:IPR003779"
                     /db_xref="InterPro:IPR012788"
                     /db_xref="GeneID:5319102"
                     /translation="MSDAFAHSARYRQGIATRRAVLGEDHVERAQQTSTDFDRPFQDL
                     ITEAAWGHVWSRPGWTKRERSIVTIALLAALGQDEEVAMHVRATANTGATREDICETL
                     LHVAIYAGVPAANHAIKIVKQVFGEMDASTASR"
     misc_feature    689528..689890
                     /locus_tag="Smed_4207"
                     /note="4-carboxymuconolactone decarboxylase; Region:
                     decarb_PcaC; TIGR02425"
                     /db_xref="CDD:131478"
     gene            689929..690690
                     /locus_tag="Smed_4208"
                     /db_xref="GeneID:5319103"
     CDS             689929..690690
                     /locus_tag="Smed_4208"
                     /note="TIGRFAM: protocatechuate 3,4-dioxygenase, beta
                     subunit;
                     PFAM: intradiol ring-cleavage dioxygenase;
                     KEGG: sme:SMb20577 protocatechuate 3,4-dioxygenase, beta
                     subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="protocatechuate 3,4-dioxygenase subunit beta"
                     /protein_id="YP_001312946.1"
                     /db_xref="GI:150376350"
                     /db_xref="InterPro:IPR000627"
                     /db_xref="InterPro:IPR012785"
                     /db_xref="GeneID:5319103"
                     /translation="MSGDQSGGENDRPETGAFFARDRAWHPPAFAPGYKSSVLRSPQK
                     ALLSLDGTLSEITGPVFGHSMLGELDNDLIHNFAKPGESAIGERIIVHGRVLDERGRP
                     VQDALVEFWQANAGGRYRHRKESYLAALDPNFGGCGRAITNGDGHYCFRTVKPGAYPW
                     PNGVNDWRPAHIHFSIFGHGFAQRLITQMYFEGDPMIWKCPIVGAIPDRRAIEQLIAA
                     LDWGNTVPMDARAYKFDIVLRGRRSTFFENRPEGN"
     misc_feature    689989..690657
                     /locus_tag="Smed_4208"
                     /note="Protocatechuate 3,4-dioxygenase (3,4-PCD) , beta
                     subunit. 3,4-PCD catalyzes the oxidative ring cleavage of
                     3,4-dihydroxybenzoate to produce
                     beta-carboxy-cis,cis-muconate. 3,4-PCDs are large
                     aggregates of 12 protomers, each composed of an alpha-
                     and...; Region: 3,4-PCD_beta; cd03464"
                     /db_xref="CDD:239547"
     misc_feature    order(689989..689991,690001..690015,690028..690030,
                     690034..690060,690067..690069,690073..690084,
                     690094..690108,690121..690123,690220..690222,
                     690253..690255,690259..690261,690283..690291,
                     690337..690339,690343..690345,690478..690480,
                     690484..690492,690496..690498,690532..690534,
                     690559..690561,690571..690573,690637..690639,
                     690643..690645)
                     /locus_tag="Smed_4208"
                     /note="heterodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239547"
     misc_feature    order(689989..689991,689995..690015,690019..690021,
                     690028..690033,690037..690084,690097..690111,
                     690121..690123,690178..690180,690184..690192,
                     690196..690198,690220..690222,690253..690255,
                     690259..690261,690274..690276,690283..690294,
                     690304..690309,690337..690339,690343..690345,
                     690397..690399,690403..690405,690412..690423,
                     690427..690429,690445..690447,690478..690492,
                     690496..690498,690502..690507,690523..690525,
                     690532..690534,690541..690543,690559..690561,
                     690568..690570,690580..690585,690589..690615,
                     690634..690639,690643..690645)
                     /locus_tag="Smed_4208"
                     /note="multimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239547"
     misc_feature    690004..690672
                     /locus_tag="Smed_4208"
                     /note="protocatechuate 3,4-dioxygenase, beta subunit;
                     Region: protocat_beta; TIGR02422"
                     /db_xref="CDD:131475"
     misc_feature    order(690028..690030,690283..690285,690400..690402,
                     690406..690408,690439..690441,690445..690447,
                     690532..690534)
                     /locus_tag="Smed_4208"
                     /note="active site"
                     /db_xref="CDD:239547"
     gene            690701..691315
                     /locus_tag="Smed_4209"
                     /db_xref="GeneID:5319219"
     CDS             690701..691315
                     /locus_tag="Smed_4209"
                     /EC_number="1.13.11.3"
                     /note="TIGRFAM: protocatechuate 3,4-dioxygenase, alpha
                     subunit;
                     PFAM: intradiol ring-cleavage dioxygenase;
                     KEGG: sme:SMb20576 putative protocatechuate
                     3,4-dioxygenase alpha chain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="protocatechuate 3,4-dioxygenase subunit alpha"
                     /protein_id="YP_001312947.1"
                     /db_xref="GI:150376351"
                     /db_xref="InterPro:IPR000627"
                     /db_xref="InterPro:IPR012786"
                     /db_xref="GeneID:5319219"
                     /translation="MAQDLGYLKETASQTAGPYVHIGLTPNFCGIGGVYEADLGASMV
                     NDRTLGQRITVTGRVIDGAGMPLKDALLEIWQADAAGLYNSPSERRGAADPNFAGWGR
                     SPTGADDGMFTFETVKPGRVPFHDGRLMAPHISFWIVARGINIGLHTRMYFPDEAVAN
                     AADPLLARIEHRHRAETLVAAGRTPNYVFDIHLQGEKETVFLDI"
     misc_feature    690701..691312
                     /locus_tag="Smed_4209"
                     /note="Protocatechuate 3,4-dioxygenase beta subunit
                     [Secondary metabolites biosynthesis, transport, and
                     catabolism]; Region: PcaH; COG3485"
                     /db_xref="CDD:226016"
     misc_feature    690722..691309
                     /locus_tag="Smed_4209"
                     /note="Protocatechuate 3,4-dioxygenase (3,4-PCD) , alpha
                     subunit. 3,4-PCD catalyzes the oxidative ring cleavage of
                     3,4-dihydroxybenzoate to produce
                     beta-carboxy-cis,cis-muconate. 3,4-PCDs are large
                     aggregates of 12 protomers, each composed of an alpha-
                     and...; Region: 3,4-PCD_alpha; cd03463"
                     /db_xref="CDD:239546"
     misc_feature    order(690722..690748,690755..690757,690761..690772,
                     690881..690889,690905..690907,690917..690919,
                     690923..690925,690947..690949,690953..690961,
                     691004..691006,691088..691090,691097..691099,
                     691121..691126,691133..691135,691148..691150,
                     691220..691222,691277..691282,691292..691294,
                     691301..691309)
                     /locus_tag="Smed_4209"
                     /note="heterodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239546"
     misc_feature    order(690752..690754,691121..691123)
                     /locus_tag="Smed_4209"
                     /note="active site"
                     /db_xref="CDD:239546"
     gene            691401..692456
                     /locus_tag="Smed_4210"
                     /db_xref="GeneID:5319220"
     CDS             691401..692456
                     /locus_tag="Smed_4210"
                     /EC_number="5.5.1.2"
                     /note="Catalyzes the cycloisomerization of
                     cis,cis-muconate"
                     /codon_start=1
                     /transl_table=11
                     /product="3-carboxy-cis,cis-muconate cycloisomerase"
                     /protein_id="YP_001312948.1"
                     /db_xref="GI:150376352"
                     /db_xref="InterPro:IPR000362"
                     /db_xref="InterPro:IPR012789"
                     /db_xref="GeneID:5319220"
                     /translation="MTYSAFDHPYLSGLLGEEAVAAEFSVAADVRAMLAFEAALARAE
                     ARHGIIPEAAANRINEACRAFSPDVGAMRRATAVDGVVVPELVRQLRRAVGEEAAEHV
                     HLGATSQDVIDTSLMLRLKALAELFSGRLGSVLTALEACEREWGERPLTAHTRMQPAL
                     TITVADRLRSWIEPLLDHQDRLDAADLDLFAVQFGGATGNLEKLKGKADIVRATLAEE
                     LALVDCPQWHSQRSPIADIAHLLSLVTGSLGKFGQDVALMAQAGDEIVLAGGGASSAM
                     SHKQNPVAAEVLVTLARFNATQVSAIHQSLVHEQERSGSAWTLEWLILPQMVGATAAA
                     LRLAAELAGNIRRLGRV"
     misc_feature    691401..692453
                     /locus_tag="Smed_4210"
                     /note="3-carboxy-cis,cis-muconate cycloisomerase;
                     Provisional; Region: PRK05975"
                     /db_xref="CDD:168324"
     misc_feature    691539..>692387
                     /locus_tag="Smed_4210"
                     /note="Adenylosuccinate lyase [Nucleotide transport and
                     metabolism]; Region: PurB; COG0015"
                     /db_xref="CDD:223094"
     misc_feature    order(691908..691910,691929..691931,691938..691943,
                     691950..691952,692106..692108,692136..692141,
                     692148..692150,692157..692162,692247..692249,
                     692256..692258,692265..692267,692274..692279)
                     /locus_tag="Smed_4210"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176466"
     gene            complement(692536..695163)
                     /locus_tag="Smed_4211"
                     /db_xref="GeneID:5319221"
     CDS             complement(692536..695163)
                     /locus_tag="Smed_4211"
                     /EC_number="5.4.99.15"
                     /note="KEGG: sme:SMb20574 putative maltooligosyl trehalose
                     synthase protein;
                     TIGRFAM: malto-oligosyltrehalose synthase;
                     PFAM: alpha amylase catalytic region;
                     SMART: alpha amylase catalytic sub domain"
                     /codon_start=1
                     /transl_table=11
                     /product="maltooligosyl trehalose synthase"
                     /protein_id="YP_001312949.1"
                     /db_xref="GI:150376353"
                     /db_xref="InterPro:IPR006047"
                     /db_xref="InterPro:IPR006589"
                     /db_xref="InterPro:IPR012767"
                     /db_xref="GeneID:5319221"
                     /translation="MHLPDATYRLQFRNGMDFAKAVELIPHFVGLGVSHLYASPLFTA
                     VRGSTHGYDIVCYDEIDPSLGGYDGFVRLVHTLKVEGLGLVLDIVPNHMAAHLENDWW
                     HSVIEWGRVSEFADHFDIDWGAPLTLPFLGRSFEDEVAAGNLRLAYDHERRCLALDYY
                     GALYPLNPATYAAIPRSGNAVLERIAAIAGTAERKTAAQFHAEIAAVVATPSLAAELD
                     QYLARLSADKQQLGRLHRMQSWQLMNWREARDKLSYRRFFEIAGLVGMRVEDDAVFAD
                     THRLTLALVREGLVDGLRIDHIDGLADPKGYLDRLREETGDGTYIIVEKILGENETLP
                     AGWPVEGTTGYEFISALADLLSDDTPSSWLSSEQRRSAAEAAVTGCKLQVLGRNFNTE
                     VRRLTGLVARFTGNGAPDRDEQTGEAIRRLIAALPVYRTYVGDQGAGAGDGRILDEIA
                     AKAAARAPAAGDETATIISAFKAPIDSLGGKLPAEFRTRFQQLSGAVMAKAVEDTFFY
                     RRGDYLAANEVGASPFWSPGGVGRFHAMMQDRASQMPYGLSATSTHDTKRGEDARARL
                     YVISEASDVWTAAMERWHGMNAASIFQLPDGDELEDSVEQFLYQSLLGAWPIEPLVDE
                     GDLISLRERMIAFTVKALREAKLRTSWEDPNERYEAAIKAFLGDLLDWGNRSFLGDFA
                     NTAGPFIQAGLINSLTQTLVKLTAPGIPDIYQGSERADLSLVDPDNRRGFSPHASLPQ
                     LLRSPMIADFENCKQALISIGLTYRRGRGRDCLAEATYLPVPIEGPGARHAAAFIRRN
                     KDKLALTVVPRLVFGRLEGNRLSVDPELWQNTFLVWPEGCELKPMRNLLTGGVVEPRA
                     LLDVAGIFRDFPAALLVDA"
     misc_feature    complement(692539..695163)
                     /locus_tag="Smed_4211"
                     /note="maltooligosyl trehalose synthase; Provisional;
                     Region: PRK14511"
                     /db_xref="CDD:237740"
     misc_feature    complement(<694660..695148)
                     /locus_tag="Smed_4211"
                     /note="Alpha amylase catalytic domain family; Region:
                     AmyAc_family; cl07893"
                     /db_xref="CDD:244824"
     misc_feature    complement(692866..>694464)
                     /locus_tag="Smed_4211"
                     /note="Alpha amylase catalytic domain found in
                     maltooligosyl trehalose synthase (MTSase); Region:
                     AmyAc_MTSase; cd11336"
                     /db_xref="CDD:200475"
     misc_feature    complement(order(692977..692979,692989..692991,
                     693499..693501,693607..693609,693655..693657,
                     693877..693879,694186..694188,694192..694194,
                     694276..694278,694393..694395))
                     /locus_tag="Smed_4211"
                     /note="active site"
                     /db_xref="CDD:200475"
     misc_feature    complement(order(693499..693501,694192..694194,
                     694276..694278))
                     /locus_tag="Smed_4211"
                     /note="catalytic site [active]"
                     /db_xref="CDD:200475"
     gene            695344..695901
                     /locus_tag="Smed_4212"
                     /db_xref="GeneID:5319222"
     CDS             695344..695901
                     /locus_tag="Smed_4212"
                     /note="PFAM: NADPH-dependent FMN reductase;
                     KEGG: sme:SMb20573 putative NADH-dependent FMN reductase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="YP_001312950.1"
                     /db_xref="GI:150376354"
                     /db_xref="InterPro:IPR005025"
                     /db_xref="GeneID:5319222"
                     /translation="MPQSRVVGISGNITRPSKTRAFVDHIVHRLAVDAGASAQTFDIE
                     DFGASLLPARRLDELAPEARYVVGQIVAADILVVGSPTFKGSYTGLFKHVFDLLDPAS
                     LRGKPIILSATGGGERHSLMVEHQMRPLFGFFEALAMPTAIYACDKDFADGALISEAI
                     HARVGRAIEEATQALARPGKARLAA"
     misc_feature    695356..695871
                     /locus_tag="Smed_4212"
                     /note="FMN reductase, MsuE subfamily; Region:
                     FMN_reduc_MsuE; TIGR03566"
                     /db_xref="CDD:211840"
     misc_feature    695356..695793
                     /locus_tag="Smed_4212"
                     /note="NADPH-dependent FMN reductase; Region: FMN_red;
                     pfam03358"
                     /db_xref="CDD:217511"
     gene            695936..697285
                     /locus_tag="Smed_4213"
                     /db_xref="GeneID:5319223"
     CDS             695936..697285
                     /locus_tag="Smed_4213"
                     /note="KEGG: sme:SMb21691 putative nitrilotriacetate
                     monooxygenase component A protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nitrilotriacetate monooxygenase
                     component A protein"
                     /protein_id="YP_001312951.1"
                     /db_xref="GI:150376355"
                     /db_xref="GeneID:5319223"
                     /translation="MTRQIKLGAFLPGGGQHIAAWRHPDAPADGATNFQFHRRLAETA
                     ERGLFDAYFLADNLSVGLGGREGGNAKIAGFEPVTLFAALAPLTTHLGFIATASTTYE
                     EPYTLARKFASLDLLSDGRAGWNVVTSAGDETARNFNRESQPSHAERYQRAHEHVETV
                     KALWDSWEDDAFIRDKTTGRFFDAGRVHDIDHRGKHFSVKGPLNAPRPVQGHPVVVQA
                     GQSEDGRKLAAASAEVIFTAHQSLASAQEFYRDIKARVKRAGRNPEHVLIMPGVAPFV
                     GRTEEEARSKYEELNALIVPEDGVALLNGLTGGTLDLTGYPLDEPLPVSDETEGMKSR
                     QALIRKIADEHGFTIRQLYQWIATARGHYTVVGSAEQVADQLEEWFLSDAADGFNILP
                     PWLPGALDDFVDLVIPILQKRGLFRTAYEGRTLRENLGLPRPANPWTLGRATVQAAE"
     misc_feature    695948..697183
                     /locus_tag="Smed_4213"
                     /note="nitrilotriacetate monoxygenase oxidizes
                     nitrilotriacetate utilizing reduced flavin mononucleotide
                     (FMNH2) and oxygen. The FMNH2 is provided by an
                     NADH:flavin mononucleotide (FMN) oxidorductase that uses
                     NADH to reduce FMN to FMNH2; Region:
                     Nitrilotriacetate_monoxgenase; cd01095"
                     /db_xref="CDD:238528"
     misc_feature    695954..697219
                     /locus_tag="Smed_4213"
                     /note="FMN-dependent oxidoreductase, nitrilotriacetate
                     monooxygenase family; Region: FMN_nitrolo; TIGR03860"
                     /db_xref="CDD:234375"
     misc_feature    order(695963..695965,695975..695977,696155..696157,
                     696314..696316,696380..696382,696599..696604)
                     /locus_tag="Smed_4213"
                     /note="active site"
                     /db_xref="CDD:238528"
     misc_feature    696221..696226
                     /locus_tag="Smed_4213"
                     /note="non-prolyl cis peptide bond; other site"
                     /db_xref="CDD:238528"
     gene            697302..698147
                     /locus_tag="Smed_4214"
                     /db_xref="GeneID:5319224"
     CDS             697302..698147
                     /locus_tag="Smed_4214"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20571 putative aliphatic sulfonate uptake ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001312952.1"
                     /db_xref="GI:150376356"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319224"
                     /translation="MSLQELDRSIVHDGGSVSAKADEYLRRSGTAAGGWLSRYGLLIA
                     VLALWQAASTAGWINPAVFPSVGAILSALWTGISGGALLDDIAVSLQRSGTAFAGAVV
                     LAIPLGLLMGQVRSIENALDPVLQLFRQTSALALYPVFILLLGLGEASKVFVIFWATL
                     FPLLLSTISGVKEVDSKLIEMARVYGASRLTVFRRVVLPGAVPSIFVGLRLSATTALL
                     LLIASEMIGANKGIGFQVMNAQYNFQIPLMFAAIFILAGLGLLSNYALVFAQRRLCRW
                     SDASN"
     misc_feature    697377..698144
                     /locus_tag="Smed_4214"
                     /note="ABC-type nitrate/sulfonate/bicarbonate transport
                     system, permease component [Inorganic ion transport and
                     metabolism]; Region: TauC; COG0600"
                     /db_xref="CDD:223673"
     misc_feature    697557..698036
                     /locus_tag="Smed_4214"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(697605..697610,697617..697622,697635..697637,
                     697662..697673,697677..697706,697713..697718,
                     697722..697724,697767..697772,697779..697781,
                     697785..697787,697794..697799,697803..697805,
                     697815..697820,697827..697829,697878..697880,
                     697920..697925,697932..697934,697953..697964,
                     697971..697976,698013..698018)
                     /locus_tag="Smed_4214"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(697680..697724,697953..697970)
                     /locus_tag="Smed_4214"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(697722..697724,697752..697754,697971..697973,
                     698007..698009,698016..698018)
                     /locus_tag="Smed_4214"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(697830..697868,697884..697889,697899..697901)
                     /locus_tag="Smed_4214"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            698195..699187
                     /locus_tag="Smed_4215"
                     /db_xref="GeneID:5319225"
     CDS             698195..699187
                     /locus_tag="Smed_4215"
                     /note="PFAM: NMT1/THI5 like domain protein;
                     KEGG: sme:SMb20570 putative aliphatic sulfonates uptake
                     ABC transporter periplasmic solute-binding protein
                     precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="NMT1/THI5-like domain-containing protein"
                     /protein_id="YP_001312953.1"
                     /db_xref="GI:150376357"
                     /db_xref="InterPro:IPR015168"
                     /db_xref="GeneID:5319225"
                     /translation="MTISIRAFALGSLVAIGFSSLAAAEAQEPVTLRFLASQGSLSPH
                     ELAYELGYFDGLGIKLENVGYAGGGPASLFALASGSVDIGSAATAAVINSIAGGNDFV
                     AAFPTNGINEQVKSIFYVLEDSPIRTIEDIAGKTIAVNTLGAHLDYAIREALHSNGLP
                     ENAANLVVVPGPQLEQTLRSNQVDISAVGYWQATFNGQLVANGGVRAVFDDTDVLGEI
                     AGGFAVLRRDFVEKNPDAARRFVEQSARAADWSREHPDEARALLARILTERGENGDLA
                     KHWTGFGLRKGAKATERDLDFWIGVLEREGSLPRGKYKASDLLFRPDAKSAASN"
     misc_feature    698195..699184
                     /locus_tag="Smed_4215"
                     /note="ABC-type nitrate/sulfonate/bicarbonate transport
                     systems, periplasmic components [Inorganic ion transport
                     and metabolism]; Region: TauA; COG0715"
                     /db_xref="CDD:223787"
     sig_peptide     698195..698269
                     /locus_tag="Smed_4215"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.538 at
                     residue 25"
     misc_feature    698360..698923
                     /locus_tag="Smed_4215"
                     /note="Bacterial periplasmic transport systems use
                     membrane-bound complexes and substrate-bound,
                     membrane-associated, periplasmic binding proteins (PBPs)
                     to transport a wide variety of  substrates, such as, amino
                     acids, peptides, sugars, vitamins and inorganic...;
                     Region: PBPb; cd00134"
                     /db_xref="CDD:238078"
     misc_feature    order(698393..698395,698474..698476,698627..698629,
                     698783..698785)
                     /locus_tag="Smed_4215"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238078"
     misc_feature    order(698720..698722,698738..698740)
                     /locus_tag="Smed_4215"
                     /note="membrane-bound complex binding site; other site"
                     /db_xref="CDD:238078"
     misc_feature    698855..698863
                     /locus_tag="Smed_4215"
                     /note="hinge residues; other site"
                     /db_xref="CDD:238078"
     gene            699198..699968
                     /locus_tag="Smed_4216"
                     /db_xref="GeneID:5319226"
     CDS             699198..699968
                     /locus_tag="Smed_4216"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20569 putative ABC transporter ATP-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312954.1"
                     /db_xref="GI:150376358"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319226"
                     /translation="MAEVRSLRRGEVALRDLSKSFRINGRPLSVLRNLNLDIRSGECL
                     AIVGASGSGKTTLLRVLAGLETADSGRALIDGRPVTGVGRERAVIFQEPRLLPWLTVL
                     GNVAFGLEVRGEDPGRADERARHYIALVGLADFQDAYPKQLSGGMAQRVGLARALTVQ
                     PEILLLDEPLGALDAMTKLTMQQELERIWREENVTMVLVTHDLEEALYLADRVLILPK
                     QKDASPRLIGIDLPRPRDRSEARFVRYRQELLREFGLH"
     misc_feature    699231..699959
                     /locus_tag="Smed_4216"
                     /note="ABC-type nitrate/sulfonate/bicarbonate transport
                     system, ATPase component [Inorganic ion transport and
                     metabolism]; Region: TauB; COG1116"
                     /db_xref="CDD:224041"
     misc_feature    699231..699845
                     /locus_tag="Smed_4216"
                     /note="ATP-binding cassette domain of the nitrate and
                     sulfonate transporters; Region:
                     ABC_NrtD_SsuB_transporters; cd03293"
                     /db_xref="CDD:213260"
     misc_feature    699339..699362
                     /locus_tag="Smed_4216"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213260"
     misc_feature    order(699348..699353,699357..699365,699468..699470,
                     699696..699701,699798..699800)
                     /locus_tag="Smed_4216"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213260"
     misc_feature    699459..699470
                     /locus_tag="Smed_4216"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213260"
     misc_feature    699624..699653
                     /locus_tag="Smed_4216"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213260"
     misc_feature    699684..699701
                     /locus_tag="Smed_4216"
                     /note="Walker B; other site"
                     /db_xref="CDD:213260"
     misc_feature    699708..699719
                     /locus_tag="Smed_4216"
                     /note="D-loop; other site"
                     /db_xref="CDD:213260"
     misc_feature    699786..699806
                     /locus_tag="Smed_4216"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213260"
     gene            700245..701417
                     /locus_tag="Smed_4217"
                     /db_xref="GeneID:5319227"
     CDS             700245..701417
                     /locus_tag="Smed_4217"
                     /note="PFAM: Extracellular ligand-binding receptor;
                     KEGG: sme:SMb20568 putative amino acid uptake ABC
                     transporter solute-binding protein, LeuIle/Val-binding
                     protein family"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular ligand-binding receptor"
                     /protein_id="YP_001312955.1"
                     /db_xref="GI:150376359"
                     /db_xref="InterPro:IPR000709"
                     /db_xref="InterPro:IPR001828"
                     /db_xref="GeneID:5319227"
                     /translation="MRRIILAALAALVTSAAAHADAIKVGVVGPFSGPFALQGKNFKA
                     GIDAYMALSGVKVGEDDIEIIYRDVPQADPAQSKALAQELVVKEGVQYLAGFYFTPDA
                     MAVTPLLEQANVPLVIMNAATSAIVTKSPLVVRTSFTLWQTSTPIAKVAREAGVSKII
                     SVVSDYGPGIDAENAFKTGFEAVGGQVVEAIRMPLSTNDFSPIMQRIKDSGAEGVFAF
                     LPSGPTTLGFVKAFNENGLKDGGVKFFAPGDLTQESDLPALGDAALGLQTTFHYSVSH
                     DSPENKAFVEAAAKAIGNPTELSFPSVGAYDGMHVIYKMIEATGGEQNAQKAVDAVKG
                     LSWTSPRGPVSIDPESRHITQNIYLREVSKADDGTYYNKEIQTFEKQGDPGLAALK"
     sig_peptide     700245..700307
                     /locus_tag="Smed_4217"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.995 at
                     residue 21"
     misc_feature    700311..701369
                     /locus_tag="Smed_4217"
                     /note="ABC-type branched-chain amino acid transport
                     systems, periplasmic component [Amino acid transport and
                     metabolism]; Region: LivK; COG0683"
                     /db_xref="CDD:223755"
     misc_feature    700314..701330
                     /locus_tag="Smed_4217"
                     /note="Type 1 periplasmic binding fold superfamily;
                     Region: Periplasmic_Binding_Protein_Type_1; cl10011"
                     /db_xref="CDD:245225"
     gene            701534..702397
                     /locus_tag="Smed_4218"
                     /db_xref="GeneID:5319228"
     CDS             701534..702397
                     /locus_tag="Smed_4218"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20787 putative branched-chain amino acid
                     uptake ABC transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="YP_001312956.1"
                     /db_xref="GI:150376360"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5319228"
                     /translation="MQTIFSIAVDALAYGMVLFVISIGLSVTLGLMRVVNLAHGAFAM
                     IGGYIASYAARDLGVGYGLAVLIAVFGTIVIAIPIERLLYRRIYGRPELTQVLMTIGI
                     TFCIIGIANYVFGPTLKTIPLPPSLQGSADLGFRSIAVHRIFAIVCGLCVAAALWYAI
                     ERTAFGVRLRAAVDDAAMAAALGVRTEVIYAVSFAVAVGLAAFGGVVGAELLPVEPYY
                     ALRYMVTFLVVVSVGGAGSIPGALAACLLLGGIDTTGRYLMPEFGEFFFYLAVIAIVC
                     VFPRGLAGRMK"
     misc_feature    701564..702379
                     /locus_tag="Smed_4218"
                     /note="Transmembrane subunit (TM) of Escherichia coli LivH
                     and related proteins. LivH is one of two TMs of the E.
                     coli LIV-1/LS transporter, a Periplasmic Binding Protein
                     (PBP)-dependent ATP-Binding Cassette (ABC) transporter
                     involved in the uptake of...; Region: TM_PBP1_LivH_like;
                     cd06582"
                     /db_xref="CDD:119324"
     misc_feature    702062..702118
                     /locus_tag="Smed_4218"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119324"
     gene            702398..703405
                     /locus_tag="Smed_4219"
                     /db_xref="GeneID:5319293"
     CDS             702398..703405
                     /locus_tag="Smed_4219"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20786 putative branched-chain amino acid
                     uptake ABC transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="YP_001312957.1"
                     /db_xref="GI:150376361"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5319293"
                     /translation="MTTATTNQAEAPLLSGRHGLGRDLAALAVILVLAVIGYLLFPNN
                     LALLTRIMAIALLVLSLDLVTGYCGVATLGHAALFGSGAYAAGIAAVHFGITDPLLMV
                     AAGIIGGALAGLVCGVVILRAHGLPQLVLSIALIHLFHEFANKASSWTGGSDGLAGIA
                     PDPLFGIFAYDLWGRTAYVFAVVLLAIVFMFLRLVVRSPFGMLCRGIKEDPIRIQAMG
                     GSPTIALLKMYVISGAVAGVGGALNAVSTQVVGLDSLSFTLSAESLVMLVLGGTGSLF
                     GAVTGTIVFMLFEDLVSAANPFHWLTMVGALLIAVVLFAPKGLYGTVAEVLARRRGAG
                     R"
     misc_feature    702509..703384
                     /locus_tag="Smed_4219"
                     /note="ABC-type branched-chain amino acid transport
                     system, permease component [Amino acid transport and
                     metabolism]; Region: LivM; COG4177"
                     /db_xref="CDD:226645"
     misc_feature    702548..703360
                     /locus_tag="Smed_4219"
                     /note="Transmembrane subunit (TM) of Escherichia coli LivM
                     and related proteins. LivM is one of two TMs of the E.
                     coli LIV-1/LS transporter, a Periplasmic Binding Protein
                     (PBP)-dependent ATP-Binding Cassette (ABC) transporter
                     involved in the uptake of...; Region: TM_PBP1_LivM_like;
                     cd06581"
                     /db_xref="CDD:119323"
     misc_feature    703031..703087
                     /locus_tag="Smed_4219"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119323"
     gene            703402..704166
                     /locus_tag="Smed_4220"
                     /db_xref="GeneID:5319294"
     CDS             703402..704166
                     /locus_tag="Smed_4220"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20785 putative branched-chain amino acid
                     uptake ABC transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312958.1"
                     /db_xref="GI:150376362"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319294"
                     /translation="MSAIFEVRNLKRSFGGLAVTNDVSLSMAPGDRVALIGPNGAGKT
                     TFVNLVTGNLEPDAGEVRIGGESVTNVNAIDRVRRGLVRSFQVTRLFQDMTPAEHVAL
                     AILQRDGRAGRMFGNFLSMPGVMAEVGVLIGKLGLRDLAHRPVREIAYGQQRLLEIAM
                     ALALKPRVLLLDEPAAGVPQSDTGRIERALADLPDDLAVLMIEHDMDLVFRFAKRVIV
                     LAAGTVIFDGSPADVTKDPRVREAYLGSYADASSAA"
     misc_feature    703402..704139
                     /locus_tag="Smed_4220"
                     /note="ABC-type branched-chain amino acid transport
                     systems, ATPase component [Amino acid transport and
                     metabolism]; Region: LivG; COG0411"
                     /db_xref="CDD:223488"
     misc_feature    703417..704118
                     /locus_tag="Smed_4220"
                     /note="ATP-binding cassette component of branched chain
                     amino acids transport system; Region:
                     ABC_Mj1267_LivG_branched; cd03219"
                     /db_xref="CDD:213186"
     misc_feature    703510..703533
                     /locus_tag="Smed_4220"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213186"
     misc_feature    order(703519..703524,703528..703536,703657..703659,
                     703915..703920,704011..704013)
                     /locus_tag="Smed_4220"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213186"
     misc_feature    703648..703659
                     /locus_tag="Smed_4220"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213186"
     misc_feature    703843..703872
                     /locus_tag="Smed_4220"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213186"
     misc_feature    703903..703920
                     /locus_tag="Smed_4220"
                     /note="Walker B; other site"
                     /db_xref="CDD:213186"
     misc_feature    703927..703938
                     /locus_tag="Smed_4220"
                     /note="D-loop; other site"
                     /db_xref="CDD:213186"
     misc_feature    703999..704019
                     /locus_tag="Smed_4220"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213186"
     gene            704147..704872
                     /locus_tag="Smed_4221"
                     /db_xref="GeneID:5319295"
     CDS             704147..704872
                     /locus_tag="Smed_4221"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20784 putative branched-chain amino acid
                     uptake ABC transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001312959.1"
                     /db_xref="GI:150376363"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319295"
                     /translation="MPAAPLEVDNLSAGYGPTRVLEGISFSVSAGAKLAVLGRNGMGK
                     TTLLATLAGQTRRYDGRIRIGEADVTALSSASRALKGLGFVPQARCVFPSLTVEENLF
                     VGLKGRAKTALNEAYEMFPRLYERRRNLGSQLSGGEQQMLSTARSILGRPSILLLDEP
                     LEGLAPVICEELMKAFAQLARTGDMTILLVEQRIRSALDFADRVIILERGRLAWSGTP
                     KALVKEPATVEQLLGIGGLAPSP"
     misc_feature    704153..704848
                     /locus_tag="Smed_4221"
                     /note="ABC-type branched-chain amino acid transport
                     systems, ATPase component [Amino acid transport and
                     metabolism]; Region: LivF; COG0410"
                     /db_xref="CDD:223487"
     misc_feature    704162..704809
                     /locus_tag="Smed_4221"
                     /note="ATP-binding cassette domain of branched-chain amino
                     acid transporter; Region: ABC_TM1139_LivF_branched;
                     cd03224"
                     /db_xref="CDD:213191"
     misc_feature    704258..704281
                     /locus_tag="Smed_4221"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213191"
     misc_feature    order(704267..704272,704276..704284,704405..704407,
                     704618..704623,704720..704722)
                     /locus_tag="Smed_4221"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213191"
     misc_feature    704396..704407
                     /locus_tag="Smed_4221"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213191"
     misc_feature    704546..704575
                     /locus_tag="Smed_4221"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213191"
     misc_feature    704606..704623
                     /locus_tag="Smed_4221"
                     /note="Walker B; other site"
                     /db_xref="CDD:213191"
     misc_feature    704630..704641
                     /locus_tag="Smed_4221"
                     /note="D-loop; other site"
                     /db_xref="CDD:213191"
     misc_feature    704708..704728
                     /locus_tag="Smed_4221"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213191"
     gene            complement(704900..705664)
                     /locus_tag="Smed_4222"
                     /db_xref="GeneID:5319296"
     CDS             complement(704900..705664)
                     /locus_tag="Smed_4222"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20773 putative transcriptional regulator,
                     GntR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312960.1"
                     /db_xref="GI:150376364"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5319296"
                     /translation="MTEKAPIQSDVLKGETARRSEAQTRQMNEIKSLEQRPVGGPGPI
                     RRTALHDTLVGHLRDMIIEGNLPPGTRLHEGQLGEQLGVSRTPLREAIKYLASEGLVE
                     LVPSRGAVVKRFSAKDVRDMLTVLQTLEELAGRLACETATDAEIAEVRALHDEMVRRY
                     EAGDRMQYYKLNQEIHTAIARLSRNAALADMHAMLQTRLKRIRFIGHEGPEKWAAAVA
                     EHQEMIAALEARDEVTLSEVLGRHLTKAWERVREAV"
     misc_feature    complement(704903..705565)
                     /locus_tag="Smed_4222"
                     /note="Transcriptional regulators [Transcription]; Region:
                     GntR; COG1802"
                     /db_xref="CDD:224715"
     misc_feature    complement(705329..705520)
                     /locus_tag="Smed_4222"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(705338..705349,705353..705358,
                     705386..705388,705395..705400,705404..705418,
                     705440..705445,705515..705517))
                     /locus_tag="Smed_4222"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(704936..705304)
                     /locus_tag="Smed_4222"
                     /note="FCD domain; Region: FCD; pfam07729"
                     /db_xref="CDD:219539"
     gene            705785..706831
                     /gene="pdxA"
                     /locus_tag="Smed_4223"
                     /db_xref="GeneID:5319297"
     CDS             705785..706831
                     /gene="pdxA"
                     /locus_tag="Smed_4223"
                     /EC_number="1.1.1.262"
                     /note="catalyzes oxidation of
                     4-(phosphohydroxy)-L-threonine into
                     2-amino-3-oxo-4-(phosphohydroxy)butyric acid which
                     decarboxylates to form
                     1-amino-3-(phosphohydroxy)propan-2-one
                     (3-amino-2-oxopropyl phosphate)"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase"
                     /protein_id="YP_001312961.1"
                     /db_xref="GI:150376365"
                     /db_xref="InterPro:IPR005255"
                     /db_xref="GeneID:5319297"
                     /translation="MTTPGADGTEERRTVIALAMGDPAGISPELTARLLALSDIREAV
                     HIIAIGDRRILDEGARVAGVTLDLESVSLDSLDRSGTARHVFVDLAHLDPADVVRGEA
                     TLAGGTFATRNFRTALELAHAGKAEAVCFTPFNKKAMRFAYPGYDDEIRFVADVLSFT
                     GKVREFNVLEKVWNARVTSHIPLKDVAAHLSVDAILAEINLTQACLKDAGYEEARIAV
                     AGLNPHAGDGGSFGMEEIDIIEPAVEKARALGFNVEGPFPADTVFLRALKEGFNAVMT
                     MYHDQGQIAMKIIGFDKGVTMMGGLAFPLCTPAHGTAYDIAGKGIADIGATREAILLA
                     ARMAKKKRALPAAA"
     misc_feature    705815..706750
                     /gene="pdxA"
                     /locus_tag="Smed_4223"
                     /note="4-hydroxythreonine-4-phosphate dehydrogenase;
                     Validated; Region: pdxA; PRK03743"
                     /db_xref="CDD:179641"
     misc_feature    705827..706771
                     /gene="pdxA"
                     /locus_tag="Smed_4223"
                     /note="4-hydroxythreonine-4-phosphate dehydrogenase;
                     Reviewed; Region: pdxA; PRK00232"
                     /db_xref="CDD:234696"
     gene            706907..707893
                     /locus_tag="Smed_4224"
                     /db_xref="GeneID:5319298"
     CDS             706907..707893
                     /locus_tag="Smed_4224"
                     /note="PFAM: Uncharacterized protein UPF0065;
                     KEGG: sme:SMb20771 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312962.1"
                     /db_xref="GI:150376366"
                     /db_xref="InterPro:IPR005064"
                     /db_xref="GeneID:5319298"
                     /translation="MKKSVSIAAVVAAAVGLAAPASAFEPNRPVEFVVTAGPGGGTDI
                     FARTIQAIIGKYELMKAPVVVTNKGSAGGAEGFVYTAGHKGDPYKLAFGTNNAYLLPV
                     RAKVPYKSEDLTPVASLASDEFVLWVNGKADYATAADFVAKAKEGGLKIGGSQSKDAD
                     QILTSMINDAIGAKISYIPFKSGGEAAVQLAGEHLDANVNNPSENLGQWQAGMIKPLC
                     VFKSAKFASDAKVAGDKAWSDIPTCKEAGIPIENYAMPRTVWLPAGVEHDVVQFYADV
                     LRKVSETPEWEKYLADSSQSPGFVTGDELKAVIEKDGATVGEVLKREGWLAN"
     sig_peptide     706907..706978
                     /locus_tag="Smed_4224"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 24"
     misc_feature    706976..707887
                     /locus_tag="Smed_4224"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3181"
                     /db_xref="CDD:225722"
     gene            708000..708500
                     /locus_tag="Smed_4225"
                     /db_xref="GeneID:5319299"
     CDS             708000..708500
                     /locus_tag="Smed_4225"
                     /note="KEGG: sme:SMb20770 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312963.1"
                     /db_xref="GI:150376367"
                     /db_xref="GeneID:5319299"
                     /translation="MSENSANGISRFAVELGVAALTGVFGIAVCYGSLDIGAGWTDMG
                     PDAGYFPFYIGLLIVLGSLANIAHAFFKHRGTGEVFLDGARTRVVASFLLPIAAFAGV
                     SAWLGLYVGTALYIAATMLFQGRYKWWISLPAGLGVSIFFFIVFEIGFQVPLLKGPVE
                     AWFGIY"
     misc_feature    708042..708461
                     /locus_tag="Smed_4225"
                     /note="Tripartite tricarboxylate transporter TctB family;
                     Region: TctB; pfam07331"
                     /db_xref="CDD:219375"
     gene            708535..710073
                     /locus_tag="Smed_4226"
                     /db_xref="GeneID:5319300"
     CDS             708535..710073
                     /locus_tag="Smed_4226"
                     /note="PFAM: protein of unknown function DUF112
                     transmembrane;
                     KEGG: sme:SMb20769 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312964.1"
                     /db_xref="GI:150376368"
                     /db_xref="InterPro:IPR002823"
                     /db_xref="GeneID:5319300"
                     /translation="MENIGLLIDGFGHILSWNHILLMVVGVTLGILVGVLPGLGAPNG
                     VSLLLPLTFSMDPISAIILLSCMYWGALFGGSTTSILFNIPGEPSSVATTFDGYPMAK
                     AGHASRALTLAFVSAGLGALAGVVMITLLSGWVANFALKFSSPEYFAVYFLAFASFIS
                     MGAQSPFKTLVSMMLGFALASVGMDTISGNLRLTFDIPELIKGVSFLIAVMGLFGIGE
                     LLLTTEEGLRFEGIKARVRLSEIGRTLIEIPRYWLTIARSTIIGIWMGITPAGPTAAS
                     FMSYGVARRSARDNSMFGKGDPRGIVAPETADHSAGTSALLPMLALGVPGSATAAVMM
                     GGLMIWGLTPGPMLFTDRPDFVWGLIASMYLGNVVAVFLVIATVPLYASILRVPFSII
                     GPIIVAVIFSGAYQVANSVSDIFMVIGFGLLGYVFKKLDYPLAPLVLAMVLGDKAEDA
                     FRQSMLMSGGSLNIFWSNGLVSALMAVALALLLSPLAFLLIGSVRKRKNEVVAPGGDG
                     SPAG"
     misc_feature    708535..709941
                     /locus_tag="Smed_4226"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3333"
                     /db_xref="CDD:225870"
     gene            710118..711059
                     /locus_tag="Smed_4227"
                     /db_xref="GeneID:5319301"
     CDS             710118..711059
                     /locus_tag="Smed_4227"
                     /note="PFAM: Xylose isomerase domain protein TIM barrel;
                     KEGG: sme:SMb20768 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase domain-containing protein"
                     /protein_id="YP_001312965.1"
                     /db_xref="GI:150376369"
                     /db_xref="InterPro:IPR012307"
                     /db_xref="GeneID:5319301"
                     /translation="MAPRKWNRDNWPIAAAMIQYPKLLPDGRSVQDQSVEEWAATLAD
                     VVDAGFTELDPTDSWIRLADLSAERLDQFVKLSRSLGLNITAISTSRRSLIDPEHGAE
                     YLAYGHRVIEAAAAVGAGSVSFGFFGPLTEAQKKVLWFWTVDGVKNPDDAGTWQLAVS
                     RVRELGRHAEELGVEVSLEMYEDTYLGTADSSVRFVEEVGLANVGINADLGNLIRLHR
                     PVEHWQEMMAKVAPFAKYWHVKNYNRTEDPASGVIITHPAPLEFGLINYRAAIRMALA
                     HGFDSPFLCEHYGGDGLSVSAANRDYLRRILPRQEGH"
     misc_feature    710241..710858
                     /locus_tag="Smed_4227"
                     /note="Xylose isomerase-like TIM barrel; Region:
                     AP_endonuc_2; pfam01261"
                     /db_xref="CDD:216395"
     gene            711076..712794
                     /locus_tag="Smed_4228"
                     /db_xref="GeneID:5319302"
     CDS             711076..712794
                     /locus_tag="Smed_4228"
                     /EC_number="2.7.1.29"
                     /note="in some organisms the DhaK and DhaL subunits are
                     encoded by separate genes; in others they are fused;
                     functions along with DhaM to phosphorylate
                     dihydroxyacetone"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="YP_001312966.1"
                     /db_xref="GI:150376370"
                     /db_xref="InterPro:IPR004006"
                     /db_xref="InterPro:IPR004007"
                     /db_xref="GeneID:5319302"
                     /translation="MTTIFDAPEDFATTALAGFAAIYQRNVRLVKGGVVRSTKVPKGK
                     VAVVVGGGSGHYPAFAGYVGPGLADAAVAGDVFASPSTAAVARVCRHADQGGGVLLGF
                     GNYAGDVLNFGVAAERLRSEGIDVRILPVTDDVASAPVDSSAKRRGIAGDLVVFKIAG
                     AAAEAGKSLDEVERLARYANDRTFSFGVAFGGCTLPGAAGPLFTVPDGQMALGLGIHG
                     EPGVSEEPIATASDLAKLLTGKLLAERPAGASKAAAVLNGLGSTKYEELFVLWTAVAK
                     ELAEACVEVVDPECGEFVTSLDMQGCSLTLLWLNEELEALWRAPADAPVLRKGVIIAA
                     EPATDEIADADGPQSFAPASEASKASGKCIARLIGNIADALKEAEEELGRIDAFAGDG
                     DHGQGMRRGSAAASDAAQTAVAAGAGAASVLAAAGDAWADRAGGTSGAIWGLALRSWS
                     NAFSDEDKASDAATVEGSRLALEGVTRLGRARVGDKTLVDALVPFVETLERESAAGRP
                     LVEAWNAAATAAQEAADATSALTPKLGRARPLAEKSIGHPDAGAVSLALVARVAGAFL
                     KEAAAG"
     misc_feature    711076..712779
                     /locus_tag="Smed_4228"
                     /note="dihydroxyacetone kinase; Provisional; Region:
                     PRK14479"
                     /db_xref="CDD:237723"
     misc_feature    711076..712062
                     /locus_tag="Smed_4228"
                     /note="dihydroxyacetone kinase subunit DhaK; Provisional;
                     Region: PRK14481; cl10557"
                     /db_xref="CDD:245332"
     misc_feature    <712384..712755
                     /locus_tag="Smed_4228"
                     /note="DAK2 domain; Region: Dak2; pfam02734"
                     /db_xref="CDD:217208"
     gene            complement(712837..713451)
                     /locus_tag="Smed_4229"
                     /db_xref="GeneID:5318273"
     CDS             complement(712837..713451)
                     /locus_tag="Smed_4229"
                     /note="PFAM: transferase hexapeptide repeat containing
                     protein;
                     KEGG: sme:SMb20765 putative acetyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hexapaptide repeat-containing transferase"
                     /protein_id="YP_001312967.1"
                     /db_xref="GI:150376371"
                     /db_xref="InterPro:IPR001451"
                     /db_xref="GeneID:5318273"
                     /translation="MSEKLGLEPCIHPTASVVNSTLGRFTEIRERSRLDEVEFADYSY
                     IMQDGSIWCATVGKFVNIAAAVRINATNHPTWRATLHHFTYRAPMYWEDAEPDHDLFA
                     WRRQNRVTIGHDVWIGHGATILPGVKVGNGAVIGAGAVVSKDVAPYTIVGGVPAKLIR
                     DRFTARVGEAMDRLAWWDWDHAKLRHALDDFRELTAEEFLVRYS"
     misc_feature    complement(712843..713451)
                     /locus_tag="Smed_4229"
                     /note="phosphonate metabolim protein, transferase
                     hexapeptide repeat family; Region: phn_thr-fam; TIGR03308"
                     /db_xref="CDD:132351"
     misc_feature    complement(712912..713346)
                     /locus_tag="Smed_4229"
                     /note="Xenobiotic acyltransferase (XAT): The XAT class of
                     hexapeptide acyltransferases is composed of a large number
                     of microbial enzymes that catalyze the CoA-dependent
                     acetylation of a variety of hydroxyl-bearing acceptors
                     such as chloramphenicol and...; Region: LbH_XAT; cd03349"
                     /db_xref="CDD:100040"
     misc_feature    complement(order(712966..712968,712990..712992,
                     713038..713040,713095..713097,713104..713106,
                     713110..713112,713200..713202,713206..713208,
                     713215..713217,713230..713235,713269..713271,
                     713320..713322,713326..713328))
                     /locus_tag="Smed_4229"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100040"
     misc_feature    complement(order(712975..712977,712987..712989,
                     712993..712998,713002..713004,713026..713028,
                     713041..713046,713095..713097,713104..713106,
                     713194..713199,713227..713229,713233..713238,
                     713314..713316,713320..713322))
                     /locus_tag="Smed_4229"
                     /note="active site"
                     /db_xref="CDD:100040"
     misc_feature    complement(order(713194..713199,713236..713238,
                     713314..713316,713320..713322))
                     /locus_tag="Smed_4229"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100040"
     misc_feature    complement(order(712975..712977,712987..712989,
                     712993..712998,713002..713004,713026..713028,
                     713041..713046,713080..713082,713095..713097,
                     713104..713106,713134..713136,713227..713229,
                     713233..713235))
                     /locus_tag="Smed_4229"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:100040"
     gene            complement(713448..714155)
                     /locus_tag="Smed_4230"
                     /db_xref="GeneID:5318274"
     CDS             complement(713448..714155)
                     /locus_tag="Smed_4230"
                     /note="TIGRFAM: phosphonate C-P lyase system protein PhnL;
                     PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20764 putative phosphonate uptake ABC
                     transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="YP_001312968.1"
                     /db_xref="GI:150376372"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR012701"
                     /db_xref="GeneID:5318274"
                     /translation="MATPLVVSEVAKSFTMHLRDGVRLPVVANVSFSVRAGECVVLGG
                     PSGVGKSSILKMLYGNYGVDEGQILVEHDGRLVNLATAEPRTVLEVRRATLGYVSQFL
                     RVVPRVCALDIVAEPLQARGVTAGDARERAAELLSKLNLPKELWSLPPATFSGGEQQR
                     VNIARGFITDHKILLLDEPTASLDAKNRAVVVEMIAAKKSAGTALIGIFHDEEVREAV
                     ADRIIDVSEFSPRRYAA"
     misc_feature    complement(713451..714155)
                     /locus_tag="Smed_4230"
                     /note="ABC-type phosphonate transport system, ATPase
                     component [Inorganic ion transport and metabolism];
                     Region: PhnL; COG4778"
                     /db_xref="CDD:227118"
     misc_feature    complement(713487..714143)
                     /locus_tag="Smed_4230"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    complement(714003..714026)
                     /locus_tag="Smed_4230"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(713526..713528,713622..713627,
                     713856..713858,714000..714008,714012..714017))
                     /locus_tag="Smed_4230"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(713856..713867)
                     /locus_tag="Smed_4230"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(713670..713699)
                     /locus_tag="Smed_4230"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(713622..713639)
                     /locus_tag="Smed_4230"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(713604..713615)
                     /locus_tag="Smed_4230"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(713520..713540)
                     /locus_tag="Smed_4230"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            complement(714218..714994)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /db_xref="GeneID:5318275"
     CDS             complement(714218..714994)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="TIGRFAM: phosphonate C-P lyase system protein PhnK;
                     PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20763 putative phosphonate uptake ABC
                     transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnK"
                     /protein_id="YP_001312969.1"
                     /db_xref="GI:150376373"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR012700"
                     /db_xref="GeneID:5318275"
                     /translation="MSAVPLLKVSDVSKFYGSRIGCRNVSFELYPGEVLAIVGESGSG
                     KTTLLSCLSTRLMPTSGVVEYHMRDGQYRDLARMSEAERRFLMRTDWGFVHQNPADGL
                     RMTVSAGANVGERLMAVGDRHYGNIRAAAGDWLRRVEIEEDRIDDQPRAFSGGMRQRL
                     QIARNLVTSPRLVFMDEPTGGLDVSVQARLLDLVRGLVHDLGLAAVIVTHDLAVARLL
                     SHRMMVMKDGAVIEQGLTDRVLDDPREPYTQLLVSSILQV"
     misc_feature    complement(714221..714994)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="phosphonate C-P lyase system protein PhnK;
                     Provisional; Region: phnK; PRK11701"
                     /db_xref="CDD:183280"
     misc_feature    complement(714293..714979)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    complement(714857..714880)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(order(714365..714367,714464..714469,
                     714707..714709,714854..714862,714866..714871))
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(714707..714718)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(714512..714541)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(714464..714481)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(714446..714457)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(714359..714379)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    complement(<714230..714304)
                     /gene="phnK"
                     /locus_tag="Smed_4231"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     gene            complement(714991..715884)
                     /locus_tag="Smed_4232"
                     /db_xref="GeneID:5318276"
     CDS             complement(714991..715884)
                     /locus_tag="Smed_4232"
                     /note="PFAM: phosphonate metabolism PhnJ;
                     KEGG: sme:SMb20762 putative C-P (carbon-phosphorus) lyase
                     component protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism PhnJ"
                     /protein_id="YP_001312970.1"
                     /db_xref="GI:150376374"
                     /db_xref="InterPro:IPR010306"
                     /db_xref="GeneID:5318276"
                     /translation="MNDLANYNFAYLDEQTKRMIRRAILKAIAIPGYQVPFASREMPM
                     PYGWGTGGVQVTASILGPSDVLKVIDQGADDTTNAVSIRAFFQKVANVAVTTRTADAT
                     IIQTRHRIPEEKLGEGQTLVYQVPIPEPLRFLEPRETETRKMHALEEYGLMHVKLYED
                     IARNGHIATTYAYPVKVEGRYVMDPSPTPKFDNPKMHMSEALQLFGAGREKRIYAVPP
                     YTEVVSLDFEDHPFEVQKFDRPCALCGAENVYLDEVVLDDKGGRMFVCSDTDHCEDRR
                     AHGHAGAMLAPAAKESQEAAE"
     misc_feature    complement(715027..715884)
                     /locus_tag="Smed_4232"
                     /note="Uncharacterized enzyme of phosphonate metabolism
                     [Inorganic ion transport and metabolism]; Region: PhnJ;
                     COG3627"
                     /db_xref="CDD:226154"
     gene            complement(715881..716987)
                     /locus_tag="Smed_4233"
                     /db_xref="GeneID:5318277"
     CDS             complement(715881..716987)
                     /locus_tag="Smed_4233"
                     /note="PFAM: phosphonate metabolism;
                     KEGG: sme:SMb20761 putative C-P (carbon-phosphorus) lyase
                     component protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein"
                     /protein_id="YP_001312971.1"
                     /db_xref="GI:150376375"
                     /db_xref="InterPro:IPR008773"
                     /db_xref="GeneID:5318277"
                     /translation="MYVAVKGGEAAIANAHRLLADRRRGDRSLPSITIEQVVEQLGLA
                     VDRVMAEASLYDRALAALAVRQARGDMIEAIFILRAYRTTLPRFGYSEPVDTARMKVE
                     RRVSATYKDLPGGQLLGPTFDYTHRLLDPSLIGEDAVDEPALKEPGEHVMRVSDILDG
                     EGLIEGDGQMPEGHVMGDLTREPMEFPMARDLRLQALARGDEGFLLALAYSTQRGYGR
                     THPFVGEVRIGEVEVELELPELGFAVSLGTVRVTECQMVNQFKGSAKQPPQFTRGYGL
                     VFGQSERKAMSMSLVDRSLRTDEFDEDIVAPAQDQEFVISHADNVQATGFVEHLKLPH
                     YVDFQAELDLVRRMRREYESAQPGGKNVMKEAAE"
     misc_feature    complement(715884..716987)
                     /locus_tag="Smed_4233"
                     /note="Uncharacterized enzyme of phosphonate metabolism
                     [Inorganic ion transport and metabolism]; Region: PhnI;
                     COG3626"
                     /db_xref="CDD:226153"
     gene            complement(716992..717594)
                     /gene="phnH"
                     /locus_tag="Smed_4234"
                     /db_xref="GeneID:5318278"
     CDS             complement(716992..717594)
                     /gene="phnH"
                     /locus_tag="Smed_4234"
                     /note="PFAM: phosphonate metabolism;
                     KEGG: sme:SMb20760 putative C-P (carbon-phosphorus) lyase
                     component protein"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit"
                     /protein_id="YP_001312972.1"
                     /db_xref="GI:150376376"
                     /db_xref="InterPro:IPR008772"
                     /db_xref="GeneID:5318278"
                     /translation="MSTQSQIYGGAFAESVFEAQAVFRTLMDCFARPGTIGRLSTAAS
                     PPPPLGGASGAVALTLCDHDTPVWLSPALSKSAAPKWIAFHTGAAVTDTKNEARFAFF
                     EKGAAVPGFDQFGLGSQEYPDRSTTLVVEVEALEGGQPLIGRGPGIKNGIVIAPKGLP
                     DVFLDLWTANRAIFPRGIDLVVTSGETVLCLPRTTKLERE"
     misc_feature    complement(716995..717582)
                     /gene="phnH"
                     /locus_tag="Smed_4234"
                     /note="carbon-phosphorus lyase complex subunit; Validated;
                     Region: phnH; PRK10147"
                     /db_xref="CDD:236655"
     gene            complement(717594..718079)
                     /locus_tag="Smed_4235"
                     /db_xref="GeneID:5318279"
     CDS             complement(717594..718079)
                     /locus_tag="Smed_4235"
                     /note="PFAM: phosphonate metabolism PhnG;
                     KEGG: sme:SMb20759 putative C-P (carbon-phosphorus lyase
                     component protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism PhnG"
                     /protein_id="YP_001312973.1"
                     /db_xref="GI:150376377"
                     /db_xref="InterPro:IPR009609"
                     /db_xref="GeneID:5318279"
                     /translation="MEAVTTEAARTGEDAQIIARRRESMRLLARATLGELSAAWGAIG
                     SKPDVAPVRGPETGLVMVRGRMGGGGAPFNLGEATVSRATVRLATGEVGHGQLLGTDK
                     ERARFAAIFDALFQNDAYRAGVEALHERIAARLDAEDRRKAEETAATRVDFFTMVRGE
                     D"
     misc_feature    complement(717597..718028)
                     /locus_tag="Smed_4235"
                     /note="Phosphonate metabolism protein PhnG; Region: PhnG;
                     pfam06754"
                     /db_xref="CDD:148387"
     gene            718194..718925
                     /locus_tag="Smed_4236"
                     /db_xref="GeneID:5318280"
     CDS             718194..718925
                     /locus_tag="Smed_4236"
                     /note="TIGRFAM: phosphonates metabolism transcriptional
                     regulator PhnF;
                     PFAM: regulatory protein GntR HTH; UbiC transcription
                     regulator-associated domain protein;
                     KEGG: sme:SMb20758 putative transcriptional regulator,
                     GntR or ArsR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001312974.1"
                     /db_xref="GI:150376378"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011663"
                     /db_xref="InterPro:IPR012702"
                     /db_xref="GeneID:5318280"
                     /translation="MMKTVERQTGVALWRQIADRIRLAISNGDYDATGKVPPETTLAA
                     QFGVNRHTVRSALAALSEEGLVRAVQGRGTMIERKERVSYPISRRTRFSQGLGRQVRE
                     IGTELLEHMQVPASGDIAEALGLAAGAPLIELSTVSSGDGRPLSTAVSYYPAERFPDM
                     AEEYARLGSVTKAFAAHGLADYVRVSTEIVARHADAQELVLLKLSPGAIVMEAQSVNA
                     DLSGRPVEYARTRFAADRMKLKIET"
     misc_feature    718206..718919
                     /locus_tag="Smed_4236"
                     /note="phosphonates metabolism transcriptional regulator
                     PhnF; Region: C_P_lyase_phnF; TIGR02325"
                     /db_xref="CDD:131378"
     misc_feature    718230..718421
                     /locus_tag="Smed_4236"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    order(718233..718235,718302..718304,718308..718313,
                     718335..718349,718353..718358,718365..718367,
                     718395..718400,718404..718415)
                     /locus_tag="Smed_4236"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    718485..718907
                     /locus_tag="Smed_4236"
                     /note="UTRA domain; Region: UTRA; pfam07702"
                     /db_xref="CDD:219527"
     gene            complement(718931..721069)
                     /locus_tag="Smed_4237"
                     /db_xref="GeneID:5318281"
     CDS             complement(718931..721069)
                     /locus_tag="Smed_4237"
                     /EC_number="5.4.99.2"
                     /note="MDM; functions in conversion of succinate to
                     propionate"
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase"
                     /protein_id="YP_001312975.1"
                     /db_xref="GI:150376379"
                     /db_xref="InterPro:IPR006098"
                     /db_xref="InterPro:IPR006099"
                     /db_xref="InterPro:IPR006158"
                     /db_xref="InterPro:IPR006159"
                     /db_xref="GeneID:5318281"
                     /translation="MPDKTIKDWEALAEKELKAGPESLTWHTPEGIDVKPLYTSDDTS
                     GMGDLNSLPGFEPFLRGPRATMYAGRPWTIRQYAGFSTAEASNAFYRRNLAAGQQGVS
                     VAFDLATHRGYDSDHPRVEGDVGKAGVAIDSVEDMKILFDGIPLDRISVSMTMNGAVI
                     PILASFIVAGEEQGVSRDKLSGTIQNDILKEFMVRNTYIYPPEPSMRIVADIIEYTAK
                     EMPKFNSISISGYHMQEAGATLVQELAFTLADGREYVRAALAKGLNVDDFAGRLSFFF
                     AIGMNFFMEAAKLRAARLLWTRIMKEFKPEKASSLMLRTHCQTSGVSLQEQDPYNNII
                     RTAFEAMSAVLGGTQSLHTNSFDEAMALPTDFSARIARNTQLILQHETGVTRVVDPLA
                     GSYYVESLTNELAEKAWALIEEVEALGGMTKAVNAGLPKRLIEEAATRRQAAVDRGEE
                     VIVGVNRYRLENEQPIDILQIDNAAVRTAQIKRIEETRRRRNSQKMKEALDTLADVAR
                     SGKGNLLAAALEAARARATVGEITDAMREAFGDYTAVPEVVTDIYGRAFEGDPELGVL
                     AGRLGEVTKRLGHKPKIMVAKLGQDGHDRGSKVIASAFGDIGFDVVAGPLFQTPEEAA
                     ELALAEEVTVLGVSSLAAGHKTLMPQLAEALKERGREDIILVCGGVIPRQDYAYLMEN
                     GVSAVFGPGTHVLDAARAILDLIEGKRRNL"
     misc_feature    complement(718937..721060)
                     /locus_tag="Smed_4237"
                     /note="methylmalonyl-CoA mutase; Reviewed; Region:
                     PRK09426"
                     /db_xref="CDD:236508"
     misc_feature    complement(719450..721054)
                     /locus_tag="Smed_4237"
                     /note="Coenzyme B12-dependent-methylmalonyl coenzyme A
                     (CoA) mutase (MCM) family, Alpha subunit-like subfamily;
                     contains proteins similar to the alpha subunit of
                     Propionbacterium shermanni MCM, as well as human and E.
                     coli MCM. Members of this subfamily contain...; Region:
                     MM_CoA_mutase_alpha_like; cd03679"
                     /db_xref="CDD:239651"
     misc_feature    complement(order(719984..719989,719996..719998,
                     720023..720025,720104..720109,720116..720118,
                     720122..720124,720128..720130,720245..720247,
                     720251..720253,720257..720259,720365..720367,
                     720374..720376,720485..720490,720521..720523,
                     720608..720610,720614..720616,720689..720691,
                     720740..720742,720749..720751,720755..720757,
                     720764..720766,720839..720841,720845..720847,
                     720851..720853,720860..720862,720872..720877,
                     720881..720883))
                     /locus_tag="Smed_4237"
                     /note="active site"
                     /db_xref="CDD:239651"
     misc_feature    complement(order(720023..720025,720116..720118,
                     720122..720124,720128..720130,720245..720247,
                     720251..720253,720257..720259,720374..720379,
                     720485..720487,720521..720523,720608..720610,
                     720614..720616,720764..720766,720839..720841,
                     720845..720847,720851..720853,720860..720862,
                     720872..720877,720881..720883))
                     /locus_tag="Smed_4237"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239651"
     misc_feature    complement(order(719984..719989,719993..719998,
                     720104..720109,720365..720367,720479..720481,
                     720485..720490,720689..720691,720740..720742,
                     720749..720751,720755..720757,720839..720841))
                     /locus_tag="Smed_4237"
                     /note="coenzyme B12 binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239651"
     misc_feature    complement(718961..719326)
                     /locus_tag="Smed_4237"
                     /note="methylmalonyl CoA mutase B12 binding domain. This
                     domain binds to B12 (adenosylcobamide), which initiates
                     the conversion of succinyl CoA and methylmalonyl CoA by
                     forming an adenosyl radical, which then undergoes a
                     rearrangement exchanging a hydrogen atom...; Region:
                     MM_CoA_mut_B12_BD; cd02071"
                     /db_xref="CDD:239022"
     misc_feature    complement(order(718979..718981,718997..718999,
                     719006..719008,719060..719062,719144..719152,
                     719156..719164,719273..719275,719282..719302))
                     /locus_tag="Smed_4237"
                     /note="B12 binding site [chemical binding]; other site"
                     /db_xref="CDD:239022"
     misc_feature    complement(719291..719293)
                     /locus_tag="Smed_4237"
                     /note="cobalt ligand [ion binding]; other site"
                     /db_xref="CDD:239022"
     gene            complement(721133..723145)
                     /locus_tag="Smed_4238"
                     /db_xref="GeneID:5318282"
     CDS             complement(721133..723145)
                     /locus_tag="Smed_4238"
                     /note="PFAM: biotin/lipoyl attachment domain-containing
                     protein; ATP-dependent carboxylate-amine ligase domain
                     protein ATP-grasp; Carbamoyl-phosphate synthase L chain
                     ATP-binding; Carbamoyl-phosphate synthetase large chain
                     domain protein; biotin carboxylase domain protein; RimK
                     domain protein ATP-grasp;
                     KEGG: sme:SMb20756 putative propionyl-CoA carboxylase
                     alpha chain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase L chain
                     ATP-binding"
                     /protein_id="YP_001312976.1"
                     /db_xref="GI:150376380"
                     /db_xref="InterPro:IPR000089"
                     /db_xref="InterPro:IPR001882"
                     /db_xref="InterPro:IPR003135"
                     /db_xref="InterPro:IPR005479"
                     /db_xref="InterPro:IPR005481"
                     /db_xref="InterPro:IPR005482"
                     /db_xref="InterPro:IPR011761"
                     /db_xref="InterPro:IPR011764"
                     /db_xref="InterPro:IPR013651"
                     /db_xref="GeneID:5318282"
                     /translation="MENMFKKILIANRGEIACRVIRTAKSLDIPTVAVYSDADRDAMH
                     VRMADEAVPIGPSPSNQSYIVIDRILEAIRKTGADAVHPGYGFLSENSAFAEALEKEG
                     VTFIGPPVRAIEAMGDKITSKKLAAEAGVSTVPGHMGLIGDADEAARIAASIGFPVMI
                     KASAGGGGKGMRIAWTEDEAREGFQSSKNEAKSSFGDDRIFIEKFVTEPRHIEIQVLG
                     DKHGNIVYLGERECSIQRRNQKVIEEAPSPFLDEKTRRAMGEQAVALAKAVAYFSAGT
                     VEFIVDARGNFYFLEMNTRLQVEHPVTELVTGLDLVEQMIRVAAGEKLAFAQKDVKLD
                     GWAIESRLYAEDPYRNFLPSIGRLSRYRPPEEGPRADGTVIRNDTGVLEGGEISMYYD
                     PMIAKLCTWGPDRATAVRAMADALDAFEIEGVGHNLPFLAAVMQQDRFREGRLTTAYI
                     AEEFAGGFQGVVPDDTAARKLAAIAVSVNQTLQERASRISGTIGNHRRVIGHEWVASL
                     DGHEIQVTCEASADGTYVRFADGTSVSVATDWTPGRTRAAFNIENQPMSVKVELAGTG
                     IRLRWRGIDVVARVRSPHIAELARLMPKKLPPDTSKMLLCPMPGVVTSITVKAGETVE
                     AGQAIAVVEAMKMENILRAERRSIVKRVAIEAGASLAVDELIMEFE"
     misc_feature    complement(721136..723136)
                     /locus_tag="Smed_4238"
                     /note="Acetyl/propionyl-CoA carboxylase, alpha subunit
                     [Lipid metabolism]; Region: COG4770"
                     /db_xref="CDD:227111"
     misc_feature    complement(722810..723133)
                     /locus_tag="Smed_4238"
                     /note="Carbamoyl-phosphate synthase L chain, N-terminal
                     domain; Region: CPSase_L_chain; pfam00289"
                     /db_xref="CDD:201133"
     misc_feature    complement(722168..722794)
                     /locus_tag="Smed_4238"
                     /note="Carbamoyl-phosphate synthase L chain, ATP binding
                     domain; Region: CPSase_L_D2; pfam02786"
                     /db_xref="CDD:190425"
     misc_feature    complement(721793..722131)
                     /locus_tag="Smed_4238"
                     /note="Biotin carboxylase C-terminal domain; Region:
                     Biotin_carb_C; smart00878"
                     /db_xref="CDD:214878"
     misc_feature    complement(721139..721336)
                     /locus_tag="Smed_4238"
                     /note="The biotinyl-domain or biotin carboxyl carrier
                     protein (BCCP) domain is present in all biotin-dependent
                     enzymes, such as acetyl-CoA carboxylase, pyruvate
                     carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA
                     carboxylase, geranyl-CoA carboxylase; Region:
                     biotinyl_domain; cd06850"
                     /db_xref="CDD:133459"
     misc_feature    complement(order(721214..721216,721235..721243,
                     721268..721270))
                     /locus_tag="Smed_4238"
                     /note="carboxyltransferase (CT) interaction site; other
                     site"
                     /db_xref="CDD:133459"
     misc_feature    complement(721238..721240)
                     /locus_tag="Smed_4238"
                     /note="biotinylation site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133459"
     gene            complement(723158..724690)
                     /locus_tag="Smed_4239"
                     /db_xref="GeneID:5318000"
     CDS             complement(723158..724690)
                     /locus_tag="Smed_4239"
                     /note="PFAM: carboxyl transferase;
                     KEGG: sme:SMb20755 putative propionyl-CoA carboxylase beta
                     chain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxyl transferase"
                     /protein_id="YP_001312977.1"
                     /db_xref="GI:150376381"
                     /db_xref="InterPro:IPR000022"
                     /db_xref="InterPro:IPR000438"
                     /db_xref="InterPro:IPR011762"
                     /db_xref="InterPro:IPR011763"
                     /db_xref="GeneID:5318000"
                     /translation="MRAILEQVEARRAEARVGGGERRIAAQHGKGKLTARERIDVLLD
                     EGSFEEYDMYVTHRCVDFDMGSQKIAGDGVVTGWGTINGRQVYVFSQDFTVLGGSLSE
                     THAQKICKIMDMAARNGAPVIGLNDSGGARIQEGVSSLAGYAEVFRRNAEVSGVIPQI
                     SVIMGPCAGGAVYSPAMTDFIFMVRDSSYMFVTGPDVVKTVTNEIVTAEELGGARTHT
                     TKSSVADGAYENDIEALEHVRLLFDFLPLNNREKPPVRPFHDDPGRIEMRLDSLIPDS
                     AAKPYDMKELIIAIADEGDFFELQASFARNIITGFIRIEGQTVGVVANQPLVLAGCLD
                     IDSSRKAARFVRFCDAFSIPILTLVDVPGFLPGTAQEYGGVIKHGAKLLFAYSQATVP
                     MVTLITRKAYGGAYDVMASKHIGADVNYAWPTAEIAVMGAKGATEILYRSELGDKEKI
                     AARTKEYEERFANPFVAAERGFIDEVIMPHSSRRRIARAFASLRSKQLETRWRKHDTI
                     PL"
     misc_feature    complement(723161..724612)
                     /locus_tag="Smed_4239"
                     /note="Acetyl-CoA carboxylase, carboxyltransferase
                     component (subunits alpha and beta) [Lipid metabolism];
                     Region: COG4799"
                     /db_xref="CDD:227136"
     misc_feature    complement(<724088..724594)
                     /locus_tag="Smed_4239"
                     /note="malonate decarboxylase subunit beta; Reviewed;
                     Region: PRK07189; cl17682"
                     /db_xref="CDD:248236"
     misc_feature    complement(<723329..>723856)
                     /locus_tag="Smed_4239"
                     /note="Acetyl-CoA carboxylase alpha subunit [Lipid
                     metabolism]; Region: AccA; cl17345"
                     /db_xref="CDD:247899"
     gene            724843..726261
                     /locus_tag="Smed_4240"
                     /db_xref="GeneID:5318001"
     CDS             724843..726261
                     /locus_tag="Smed_4240"
                     /note="PFAM: helix-turn-helix domain protein; protein of
                     unknown function DUF955;
                     KEGG: sme:SMb20754 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312978.1"
                     /db_xref="GI:150376382"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="InterPro:IPR010359"
                     /db_xref="GeneID:5318001"
                     /translation="MAIGKLYIGRKVRDLRDGKRLTQAQFAERIGISTSYLNQIENNQ
                     RPVSASVLLALAEKFQIDIAELSSGESDRLLSALSEALSDPLFETYSPSLQELKLVVQ
                     NAPGLAHALISCHQAYRRNSEQLASIDDTIGRGASFVETTPYEEVRDFFHFVDNYIHE
                     IDTLAETLADELGLGDGDNHAALAAYLEERHGIRVVRGAAGDEAIRRFDPRARVLTLN
                     PYAPAATRDFQLALQIAQTRAREEIDRVAGSAGFRTEEAYEICRIGLQNYFAGALILP
                     YQPFLKAARELRHDVELLAARFGASLEQVCHRLSTLQRPGQKGIPIFFARIDRAGNIT
                     KRHSAAKLQFARFGAACPLWNVHQAFETPGRIIRQLAETPDGVRYLCLATQITKGGGG
                     YRAAHPRYALALGCEISYADAFVYADDMDLGNRAAYDPIGISCRICERTRCASRAVPP
                     LKRKLIVDHDMRGALPYRLSES"
     misc_feature    724864..725199
                     /locus_tag="Smed_4240"
                     /note="Predicted transcriptional regulators
                     [Transcription]; Region: HipB; COG1396"
                     /db_xref="CDD:224314"
     misc_feature    724867..725040
                     /locus_tag="Smed_4240"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; Region: HTH_XRE; cd00093"
                     /db_xref="CDD:238045"
     misc_feature    order(724879..724881,724891..724893,724966..724968)
                     /locus_tag="Smed_4240"
                     /note="non-specific DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238045"
     misc_feature    order(724888..724890,724963..724965)
                     /locus_tag="Smed_4240"
                     /note="salt bridge; other site"
                     /db_xref="CDD:238045"
     misc_feature    order(724909..724914,724945..724947,724954..724956,
                     724966..724971)
                     /locus_tag="Smed_4240"
                     /note="sequence-specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238045"
     misc_feature    725260..726252
                     /locus_tag="Smed_4240"
                     /note="Predicted transcriptional regulator [General
                     function prediction only]; Region: COG3800"
                     /db_xref="CDD:226322"
     misc_feature    725407..725772
                     /locus_tag="Smed_4240"
                     /note="Domain of unknown function (DUF955); Region:
                     DUF955; pfam06114"
                     /db_xref="CDD:147984"
     misc_feature    725773..726243
                     /locus_tag="Smed_4240"
                     /note="Predicted transcriptional regulator (DUF2083);
                     Region: DUF2083; pfam09856"
                     /db_xref="CDD:220444"
     gene            726483..727631
                     /locus_tag="Smed_4241"
                     /db_xref="GeneID:5318002"
     CDS             726483..727631
                     /locus_tag="Smed_4241"
                     /note="PFAM: acyl-CoA dehydrogenase domain protein;
                     Acyl-CoA dehydrogenase type 2 domain;
                     KEGG: sme:SMb20753 putative acyl-CoA dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase domain-containing
                     protein"
                     /protein_id="YP_001312979.1"
                     /db_xref="GI:150376383"
                     /db_xref="InterPro:IPR006089"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR006092"
                     /db_xref="InterPro:IPR013107"
                     /db_xref="GeneID:5318002"
                     /translation="MHMDFRLSEEQEAIRTMAFDFARDEIAPHAVDWDQQKHFPVETL
                     RAAAALGMAGIYVRDDVGGTGLTRLDAAMIIEALATGCPAIASFVSIHNMCAGMIDRY
                     GTDEQRQRLLPPLLTMDVLASYCLTEPGSGSDAAALKTKAVREGEAYLLTGQKQFISG
                     AGVSGLYIVMARTGEEGPKGISAFVVEKDAPGLTFGANEKKMGWHAQPTRAVMLDSVR
                     VPVENRLGAEGEGFRIAMAGLDGGRLNIAAASLGGAQSAFDKALAYVQGRRAFGKAIG
                     EFQALQFRLADMATDLEIARTFLWRAASALDAADPEATKLCAMAKRFVTDRCFAVAND
                     ALQLHGGYGYLADYGVEKIVRDLRVHQILEGTNEIMRLIVSRAITGRK"
     misc_feature    726489..727628
                     /locus_tag="Smed_4241"
                     /note="Acyl-CoA dehydrogenases [Lipid metabolism]; Region:
                     CaiA; COG1960"
                     /db_xref="CDD:224871"
     misc_feature    726501..727625
                     /locus_tag="Smed_4241"
                     /note="Isobutyryl-CoA dehydrogenase; Region: IBD; cd01162"
                     /db_xref="CDD:173851"
     misc_feature    order(726750..726752,726762..726764,726879..726881,
                     727176..727178,727197..727202,727209..727211,
                     727416..727418,727422..727424,727569..727574)
                     /locus_tag="Smed_4241"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173851"
     misc_feature    order(726852..726854,726858..726863,726876..726881,
                     726951..726953,726957..726959,727083..727085,
                     727557..727559,727578..727580,727584..727586)
                     /locus_tag="Smed_4241"
                     /note="FAD binding site [chemical binding]; other site"
                     /db_xref="CDD:173851"
     misc_feature    727572..727574
                     /locus_tag="Smed_4241"
                     /note="catalytic base [active]"
                     /db_xref="CDD:173851"
     gene            727644..728714
                     /locus_tag="Smed_4242"
                     /db_xref="GeneID:5318003"
     CDS             727644..728714
                     /locus_tag="Smed_4242"
                     /EC_number="4.2.1.17"
                     /note="catalyzes the formation of
                     3-hydroxy-2-methylpropanoate from
                     3-hydroxy-2-methylpropanoyl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyryl-CoA hydrolase"
                     /protein_id="YP_001312980.1"
                     /db_xref="GI:150376384"
                     /db_xref="InterPro:IPR001753"
                     /db_xref="GeneID:5318003"
                     /translation="MEMQATFPEVIVERQGAIGRLRLNRPRALNSLNRAMIRAIAAAL
                     TEFERDPAIAAVLVTGEGERGLCAGGDIRMIYESGRERPEEGAQFWREEFIVNSRISA
                     YSKPYVAIMDGIVMGGGVGVSSHGSHRIVTERTRFAMPETGIGYFTDVGATWLLPRAP
                     GEFGTYLGLTGRDIGAAAVIHARLGDSFVPSERIDELVAILASLPASAKAEDVSAAIR
                     TVSAQAPASALLDHQPVIDRCFASDTVEEILGALENEGTDFSRETLDLLKTRSAISLK
                     LTLALLRAGRASASLDECLEREYAATLGMLSNPDFYEGVRAAVIDKDRNPKWSVGLSQ
                     VTPAVLDRFQRNEGAPLFAGQA"
     misc_feature    727665..728672
                     /locus_tag="Smed_4242"
                     /note="3-hydroxyisobutyryl-CoA hydrolase; Provisional;
                     Region: PRK05617"
                     /db_xref="CDD:235533"
     misc_feature    727671..728249
                     /locus_tag="Smed_4242"
                     /note="Crotonase/Enoyl-Coenzyme A (CoA) hydratase
                     superfamily. This superfamily contains a diverse set of
                     enzymes including enoyl-CoA hydratase, napthoate synthase,
                     methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA
                     dehydratase, and dienoyl-CoA isomerase; Region:
                     crotonase-like; cd06558"
                     /db_xref="CDD:119339"
     misc_feature    order(727728..727730,727734..727736,727833..727835,
                     727845..727859,727983..727985,727989..727997,
                     728061..728066,728073..728075)
                     /locus_tag="Smed_4242"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:119339"
     misc_feature    order(727851..727853,727995..727997)
                     /locus_tag="Smed_4242"
                     /note="oxyanion hole (OAH) forming residues; other site"
                     /db_xref="CDD:119339"
     misc_feature    order(727935..727937,727959..727961,728022..728033,
                     728067..728078,728094..728096,728100..728108,
                     728112..728117,728130..728132,728136..728141,
                     728145..728150,728157..728159,728190..728192,
                     728199..728201,728244..728246)
                     /locus_tag="Smed_4242"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119339"
     misc_feature    728328..728672
                     /locus_tag="Smed_4242"
                     /note="2-enoyl-CoA Hydratase C-terminal region; Region:
                     ECH_C; pfam13766"
                     /db_xref="CDD:205939"
     gene            728767..729663
                     /locus_tag="Smed_4243"
                     /db_xref="GeneID:5318004"
     CDS             728767..729663
                     /locus_tag="Smed_4243"
                     /EC_number="1.1.1.31"
                     /note="TIGRFAM: 3-hydroxyisobutyrate dehydrogenase;
                     PFAM: NADP oxidoreductase coenzyme F420-dependent;
                     6-phosphogluconate dehydrogenase NAD-binding;
                     KEGG: sme:SMb20751 putative 3-hydroxyisobutyrate
                     dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="YP_001312981.1"
                     /db_xref="GI:150376385"
                     /db_xref="InterPro:IPR002204"
                     /db_xref="InterPro:IPR004455"
                     /db_xref="InterPro:IPR006115"
                     /db_xref="InterPro:IPR011548"
                     /db_xref="GeneID:5318004"
                     /translation="MTKIAFIGLGNMGGPMAANLVKAGHAVTGFDLLEASRNAAAKSG
                     VSVAGSIAQAVREMECVITMLPASAHVLYVWDELLGFVDPGTLLIDSSTIDVESARKV
                     HGLAEKANCPSLDAPVSGGTAGAAGATLTFMVGGSDGAFSRGKHLLEAMGKKIVHCGD
                     AGAGQAAKICNNMILGVSMAAVCEAFVLAERLGLSHQALFDVASTSSGQCWSLTTYCP
                     VPGPVPTSPANSGYKPGFAASLMLKDLKLSQQAASASGAATPMGAQAMQLYSLFEKLG
                     HGSEDFSALIHLLRGNEEGKAE"
     misc_feature    728773..>729372
                     /locus_tag="Smed_4243"
                     /note="6-phosphogluconate dehydrogenase-like protein;
                     Reviewed; Region: PRK09599"
                     /db_xref="CDD:236582"
     misc_feature    728782..729636
                     /locus_tag="Smed_4243"
                     /note="3-hydroxyisobutyrate dehydrogenase; Region: HIBADH;
                     TIGR01692"
                     /db_xref="CDD:130753"
     gene            complement(729685..730434)
                     /locus_tag="Smed_4244"
                     /db_xref="GeneID:5318005"
     CDS             complement(729685..730434)
                     /locus_tag="Smed_4244"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR; KR
                     domain protein;
                     KEGG: sme:SMb20750 putative dehydrogense, possibly
                     gluconate 5-dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001312982.1"
                     /db_xref="GI:150376386"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5318005"
                     /translation="MFDLNGKTALVTGGGRGLGLEIAKALARAGAWTVINGRNRQNLE
                     EARARLARDGIETGIAPGDITRDADAIVAAAVEKTGGLDILLHAVGERDRRGTEAMEP
                     HEFAALLNTDLTAAYAMARAALPHLRRSAAGRLIFVTSIAAFAARAGDPAYTAAKGGL
                     SALTRSLAVELGADNLTVNAIAPGWFATETNAHLAADPALTAFVDMRIPLKRWGRPEE
                     IAPAAVFLASPAASFVNGTTLTVDGGMTVQM"
     misc_feature    complement(729688..730431)
                     /locus_tag="Smed_4244"
                     /note="gluconate 5-dehydrogenase; Provisional; Region:
                     PRK06124"
                     /db_xref="CDD:235702"
     misc_feature    complement(729694..730431)
                     /locus_tag="Smed_4244"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    complement(order(729877..729888,729964..729966,
                     729976..729978,730015..730023,730165..730173,
                     730318..730326,730381..730383,730387..730392,
                     730396..730398))
                     /locus_tag="Smed_4244"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    complement(order(729964..729966,729976..729978,
                     730015..730017,730099..730101))
                     /locus_tag="Smed_4244"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            complement(730480..731940)
                     /locus_tag="Smed_4245"
                     /db_xref="GeneID:5318006"
     CDS             complement(730480..731940)
                     /locus_tag="Smed_4245"
                     /note="PFAM: Mannitol dehydrogenase domain; Mannitol
                     dehydrogenase rossman domain;
                     KEGG: sme:SMb20749 putative D-mannonate oxidoreductase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase domain-containing
                     protein"
                     /protein_id="YP_001312983.1"
                     /db_xref="GI:150376387"
                     /db_xref="InterPro:IPR000669"
                     /db_xref="InterPro:IPR013118"
                     /db_xref="InterPro:IPR013131"
                     /db_xref="GeneID:5318006"
                     /translation="MRLSQETLDRLPASVKSPAYDLGAVAVGIVHLGIGAFHRAHQAA
                     LTDALLAEDPSWGICGVSLRSPDTRDALRPQDGLYTLAVKDGAGTDFSVIGSVVELLC
                     APEDPEAVLRRMADPATRIVSLTITEKGYCHNPATGTLDENHPDIAHDLANPACPRSA
                     IGFIVEAISRRVRAGIAPFALLSCDNLPGNGNVLKRIVEQFAELRDPALAALVRNVAS
                     PSTMVDRIVPATTDADRSAVAEALGLEDAWPIMTEPFRQWVIEDDFPLGRPAWEKAGA
                     LFVDDVSAFEFMKLRLLNGSHSTLAYLGYLAGAETVADAMALPGMQALIEGLMREEVS
                     PTLPELPGFDLPAYRSELLLRFRNPALRHRTWQIAMDGSQKLPQRLLGTIRDRLQAGA
                     GYDRLALGVAAWMRYARGLDEAGGTIDVRDPHAGRIAELARGLDEPDRIVDALLTMAD
                     VFGTDLPASAPFRSALIKALAGLLQHGSAATLRSYA"
     misc_feature    complement(730486..731907)
                     /locus_tag="Smed_4245"
                     /note="Mannitol-1-phosphate/altronate dehydrogenases
                     [Carbohydrate transport and metabolism]; Region: MtlD;
                     COG0246"
                     /db_xref="CDD:223324"
     misc_feature    complement(731380..731859)
                     /locus_tag="Smed_4245"
                     /note="Mannitol dehydrogenase Rossmann domain; Region:
                     Mannitol_dh; pfam01232"
                     /db_xref="CDD:144722"
     misc_feature    complement(730570..731298)
                     /locus_tag="Smed_4245"
                     /note="Mannitol dehydrogenase C-terminal domain; Region:
                     Mannitol_dh_C; pfam08125"
                     /db_xref="CDD:149275"
     gene            732514..733578
                     /locus_tag="Smed_4246"
                     /db_xref="GeneID:5318007"
     CDS             732514..733578
                     /locus_tag="Smed_4246"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb20748 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001312984.1"
                     /db_xref="GI:150376388"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318007"
                     /translation="MHSIRDRLPVSIIIANYNYARFLNRAIDSALSQNHANVEVIVVD
                     DASTDGSADVISSYGARIKACLRKANGGHAAAFNTGFAESRGEIVFFLDADDYLYPTA
                     VSELLARWDDDTAQMQFRLHLVDEGQRVKDIFPPLEVPFDSGDVTPQLARRARYQTTV
                     TSGLAFARKALDVIMPVPEVEFRQGADGYLVTLAPLYGKVTSLDACLGAYRIHGGNHS
                     VFAEKLGQRARWRVEHDFHRLQALTEQASQVGLSISPKANLRDPVHLEERIASLCVDS
                     GRHPVAADSRLGLAAAGAVASMRMNVSLRRRAMLAAWFVSVGLLPPRMAQAVLSWKLV
                     SSSRPAFLMRLSRTIRHAMG"
     misc_feature    732541..>732849
                     /locus_tag="Smed_4246"
                     /note="Glycosyltransferases involved in cell wall
                     biogenesis [Cell envelope biogenesis, outer membrane];
                     Region: WcaA; COG0463"
                     /db_xref="CDD:223539"
     misc_feature    732544..733035
                     /locus_tag="Smed_4246"
                     /note="Glycosyl transferase family 2; Region:
                     Glycos_transf_2; pfam00535"
                     /db_xref="CDD:215980"
     misc_feature    order(732556..732558,732562..732564,732640..732642,
                     732790..732792,732796..732798)
                     /locus_tag="Smed_4246"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            complement(733651..734700)
                     /locus_tag="Smed_4247"
                     /db_xref="GeneID:5318008"
     CDS             complement(733651..734700)
                     /locus_tag="Smed_4247"
                     /EC_number="5.1.1.1"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: rxy:Rxyl_2600 transcriptional regulator, LacI
                     family"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="YP_001312985.1"
                     /db_xref="GI:150376389"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318008"
                     /translation="MVGGANKAATIREVAALAGVAPGTVSNVLTGKKLVAEPLRKAVL
                     DAIAQLDYRPNHLASSLRFGRTKSIGIVVPDMTNPFFSGLVRELELKAAKSGFQILLM
                     SSYEEAAEERERIRALVSRQVDGLIISPSRDSIETSPHSAISGIPTVLVDRAFAVEGF
                     DTVSADNEQATLMGARHLIELGHKRITFLATAPGLANMEERVSGYRKAMQDAGVSDAN
                     VVYGGLSIESCRSAIEQELRRAGRPTAVFASAYVATLGAAKAIRALDLAFPQDVSLLG
                     FDDSDWMTVLRPYVSTIEQPLDELGHACWELLQRRMKKMDVPPVHRRIACTLRAREST
                     RRIRRKSGPRSRSEV"
     misc_feature    complement(733705..734676)
                     /locus_tag="Smed_4247"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    complement(734515..734667)
                     /locus_tag="Smed_4247"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    complement(order(734515..734520,734524..734529,
                     734536..734538,734545..734547,734584..734586,
                     734593..734598,734611..734613,734620..734625,
                     734629..734643,734665..734667))
                     /locus_tag="Smed_4247"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    complement(734518..734547)
                     /locus_tag="Smed_4247"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    complement(733717..734496)
                     /locus_tag="Smed_4247"
                     /note="Ligand binding domain of the LacI tanscriptional
                     regulator family belonging to the type I
                     periplasmic-binding fold protein superfamily; Region:
                     PBP1_LacI_sugar_binding_like; cd06267"
                     /db_xref="CDD:107262"
     misc_feature    complement(order(733816..733818,733867..733869,
                     734029..734031,734098..734100,734206..734208,
                     734245..734247,734314..734316,734449..734451,
                     734458..734463))
                     /locus_tag="Smed_4247"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107262"
     misc_feature    complement(order(733912..733917,733924..733926,
                     733936..733938,734020..734022,734335..734343,
                     734350..734352,734359..734361,734392..734394,
                     734398..734412,734431..734436,734440..734445,
                     734452..734460))
                     /locus_tag="Smed_4247"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107262"
     gene            complement(734923..735948)
                     /locus_tag="Smed_4248"
                     /db_xref="GeneID:5318009"
     CDS             complement(734923..735948)
                     /locus_tag="Smed_4248"
                     /note="PFAM: D-isomer specific 2-hydroxyacid dehydrogenase
                     NAD-binding;
                     KEGG: sme:SMc00340 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding D-isomer specific 2-hydroxyacid
                     dehydrogenase"
                     /protein_id="YP_001312986.1"
                     /db_xref="GI:150376390"
                     /db_xref="InterPro:IPR006140"
                     /db_xref="GeneID:5318009"
                     /translation="MSRDVILVDPLPRTVDLIMDPSVKARLHRLGEVVISEDRPMPAE
                     QVDALLPDAVLIFGQTDMPKERLDRARKLKAIINVESNFLPNIDYQTCVERGIWVITP
                     ASAFASPVAEASLAMALDLARGITKADRDFRVGAEQYGLAGNEETFRFAGAPVGIIGF
                     GDLGQQLRELIRPFRNHVRVFDPWLPEEIVQRADCVPSSLDELLSESQVVFVFASVTS
                     ENEGFIGAREFSLMRKGAAFLLMSRAAVVDFPAMLEAAGSGHIRVATDVFPEEPVAPD
                     DPVRTTPGLLLSAHRTGGTRDAFYALGSMAVADAELIMRGLPPQLCRRADPATVRRLR
                     SKPVTVS"
     misc_feature    complement(734953..735933)
                     /locus_tag="Smed_4248"
                     /note="Putative D-isomer specific 2-hydroxyacid
                     dehydrogenases; Region: 2-Hacid_dh_8; cd12167"
                     /db_xref="CDD:240644"
     misc_feature    complement(734992..735906)
                     /locus_tag="Smed_4248"
                     /note="Phosphoglycerate dehydrogenase and related
                     dehydrogenases [Amino acid transport and metabolism];
                     Region: SerA; COG0111"
                     /db_xref="CDD:223189"
     misc_feature    complement(order(735079..735081,735220..735222,
                     735631..735633,735703..735711,735769..735771))
                     /locus_tag="Smed_4248"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:240644"
     misc_feature    complement(order(735070..735075,735079..735081,
                     735148..735153,735220..735228,735289..735291,
                     735304..735312,735400..735408,735460..735474,
                     735619..735621,735631..735633,735706..735708))
                     /locus_tag="Smed_4248"
                     /note="putative NAD binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240644"
     misc_feature    complement(order(735079..735081,735136..735138,
                     735220..735222))
                     /locus_tag="Smed_4248"
                     /note="catalytic site [active]"
                     /db_xref="CDD:240644"
     gene            736272..736946
                     /locus_tag="Smed_4249"
                     /db_xref="GeneID:5318462"
     CDS             736272..736946
                     /locus_tag="Smed_4249"
                     /note="TIGRFAM: HAD-superfamily hydrolase, subfamily IA,
                     variant 3; HAD-superfamily hydrolase, subfamily IA,
                     variant 1;
                     PFAM: Haloacid dehalogenase domain protein hydrolase;
                     KEGG: sme:SMb20747 hypothetical enzyme, haloacid
                     dehalogenaseepoxide hydrolase family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="YP_001312987.1"
                     /db_xref="GI:150376391"
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006402"
                     /db_xref="InterPro:IPR006439"
                     /db_xref="GeneID:5318462"
                     /translation="MRIEPVFLFDLDGTLVDSVYQHVLAWKEALDAEGIDLSVWRIHR
                     KIGMSGGLFADQLLRETNMEISAERVGRLRQYHAAAYKRQADSIRPLPGARELLTWLT
                     DAKISYAIATSGRMETAAVNLAALGIDPAVVPVVTRDLVKYAKPDPDLFLAAAEQLGA
                     PIETAVVVGDSIWDMLAAVRCRALAIGLLSGGYGHEELRHAGAYRIFEDPADMLHHID
                     EVGGRR"
     misc_feature    736272..736928
                     /locus_tag="Smed_4249"
                     /note="Predicted phosphatases [General function prediction
                     only]; Region: Gph; COG0546"
                     /db_xref="CDD:223620"
     misc_feature    736512..736832
                     /locus_tag="Smed_4249"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    736605..736607
                     /locus_tag="Smed_4249"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     gene            complement(736965..737150)
                     /locus_tag="Smed_4250"
                     /db_xref="GeneID:5318463"
     CDS             complement(736965..737150)
                     /locus_tag="Smed_4250"
                     /note="KEGG: sme:SMb20746 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312988.1"
                     /db_xref="GI:150376392"
                     /db_xref="GeneID:5318463"
                     /translation="MATSLYGKSATILKFPASVSRKAEERRSEAQRKPDVAPSDVCAA
                     VDGCWYHEEALVDETKH"
     misc_feature    complement(736971..737126)
                     /locus_tag="Smed_4250"
                     /note="Protein of unknown function (DUF2735); Region:
                     DUF2735; pfam10931"
                     /db_xref="CDD:220908"
     gene            737657..738691
                     /locus_tag="Smed_4251"
                     /db_xref="GeneID:5318464"
     CDS             737657..738691
                     /locus_tag="Smed_4251"
                     /EC_number="6.3.1.2"
                     /note="PFAM: glutamine synthetase catalytic region;
                     glutamine synthetase beta-Grasp;
                     KEGG: sme:SMb20745 putative glutatmine synthetase II
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="YP_001312989.1"
                     /db_xref="GI:150376393"
                     /db_xref="InterPro:IPR008146"
                     /db_xref="InterPro:IPR008147"
                     /db_xref="GeneID:5318464"
                     /translation="MTKYKLEYIWLDGYTPVPNLRGKTQIKEFDAFPTLEQLPLWGFD
                     GSSTLQAEGRSSDCVLKPVAVYPDPVRTNGALVMCEVMMPDGKTPHASNTRATVLDDE
                     GAWFGFEQEYFFYKNGRPLGFPEQGYPAPQGPYYTGVGYKNVGDVARQIVEEHLDICL
                     AAGINHEGINAEVAKGQWEFQIFGKGSKKAADEVWLARYLLLRLTEKYGIDVEFHCKP
                     LGDTDWNGSGMHANFSTAYLREVGGQDYFEALMAAFEKNLHDHINVYGPDNHLRLTGK
                     HETAPWDKFSYGVADRGASIRVPHSFVNNGYRGYLEDRRPNSQGDPYQIASIILKTIS
                     SVPTAVAKVA"
     misc_feature    737663..738655
                     /locus_tag="Smed_4251"
                     /note="glutamine synthetase; Region: PLN02284"
                     /db_xref="CDD:177922"
     misc_feature    737672..737908
                     /locus_tag="Smed_4251"
                     /note="Glutamine synthetase, beta-Grasp domain; Region:
                     Gln-synt_N; pfam03951"
                     /db_xref="CDD:217811"
     misc_feature    737951..738646
                     /locus_tag="Smed_4251"
                     /note="Glutamine synthetase, catalytic domain; Region:
                     Gln-synt_C; pfam00120"
                     /db_xref="CDD:215731"
     gene            738913..741507
                     /locus_tag="Smed_4252"
                     /db_xref="GeneID:5318465"
     CDS             738913..741507
                     /locus_tag="Smed_4252"
                     /note="TIGRFAM: outer membrane autotransporter barrel
                     domain;
                     PFAM: Autotransporter beta- domain protein;
                     KEGG: atc:AGR_pAT_528 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane autotransporter"
                     /protein_id="YP_001312990.1"
                     /db_xref="GI:150376394"
                     /db_xref="InterPro:IPR005546"
                     /db_xref="InterPro:IPR006315"
                     /db_xref="GeneID:5318465"
                     /translation="MPDISPGRTSFAASDRALRRLSILNAHVLPGAPSASSDRIRCEF
                     NKLLLGSVASIALFCSLDSEARAACVETSPGAYDCSGTGPGPTFTGQSVTINADPTAS
                     FTSDVSITGPGTSTLNNNGTLTNSLRATDNDRFTLNNRGLIDGTIFLGGSGANVIINY
                     AGGDVQNGVTSTGDSHDTVINRGFFAGSIVLGDGYDVLGLIEGTVQTSVDMGAGDDQF
                     TWLVGNIAATVQMGEGDDRAVFGSLTQQNLSAGKRVDGGLGIDTLVWENTTNDDGGGS
                     GDHPENIVNWEEIELRNGSEMTFIYSTGNLTLGDSASGTGTLSIDETSAVRAGNSFGY
                     GVRAFDPSQLVTVYNAGIIDMTNDTVNVGDLLHDTFTVYGNYVGQQGGLQLHTVLESD
                     DAPSDKLVISGTGASASGGTSILITNVGGQGALTLADGIRVVDATAGATTEGTAFTLG
                     APVAAGIFEYKLYRGGLTEDPDNDDDWFLRSGGVSPPPPPPPPPPPPPPPPPPSPPPP
                     PPPSPPPPPPPPPPPPPPPPPPPPPPGPSPITPSVRPEIPGYIVKPALMQKMGVAAIG
                     TFHERQGDQFLLNSNGYLPGAWGRLFGESFDQSWSSKISRFEFEVSPSSSGELWGLQA
                     GQDLIGALHDDGSQDRVGVFFAYTGTSGSNGGNTLGRLQVESGSIDLHANSIGAYWTH
                     IGADGWYVDSIGMYSWLDGGSNSDRGIGVDTSGNSTALSIEAGYPFRFDNGWVLEPQG
                     QLIWQHVDLDDANDRFTGIDYESFGTWTGRLGVRLEANTTMNDVPVQPFASVNLWHDF
                     DQDYKVSFNRVPVVTELEQTLLELNVGFSAQMSETVSVYGGLQFATGLDDDDNRGYGG
                     NIGLRIKW"
     misc_feature    739822..740355
                     /locus_tag="Smed_4252"
                     /note="Pertactin-like passenger domains (virulence
                     factors), C-terminal, subgroup 2, of autotransporter
                     proteins of the type V secretion system of Gram-negative
                     bacteria. This subgroup includes the passenger domains of
                     the nonprotease autotransporters, Ag43; Region:
                     PL2_Passenger_AT; cd01344"
                     /db_xref="CDD:238654"
     misc_feature    740668..741435
                     /locus_tag="Smed_4252"
                     /note="Autotransporter beta-domain; Region:
                     Autotransporter; pfam03797"
                     /db_xref="CDD:217734"
     gene            741517..742245
                     /locus_tag="Smed_4253"
                     /db_xref="GeneID:5318466"
     CDS             741517..742245
                     /locus_tag="Smed_4253"
                     /note="KEGG: xcb:XC_1509 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312991.1"
                     /db_xref="GI:150376395"
                     /db_xref="GeneID:5318466"
                     /translation="MKRLTAYVIDGHELTIRPAPLERDWMNRTNQRFAYRCLPLNIAN
                     AHGWEILNQAGFSTVWDGGERENAVRIEPDPGTHAPAVSHFGSGTLTFHIPCLFKTDG
                     GTDLFVTGPLNRPKDGIAALTGIIETDWSPYTFTMNWQFTRAGHWIRFEAGEPICHIF
                     PVSRGGLEAVTPEMRKLSENPELEGEYKAWSDSRNSFNEGLSDPNSDAVREKWQKSYF
                     RGVCPSGRNGPADHRSRLRLKPFG"
     gene            complement(742454..742687)
                     /locus_tag="Smed_4254"
                     /db_xref="GeneID:5318467"
     CDS             complement(742454..742687)
                     /locus_tag="Smed_4254"
                     /note="KEGG: sme:SMb20727 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312992.1"
                     /db_xref="GI:150376396"
                     /db_xref="GeneID:5318467"
                     /translation="MHCKTTLPGPSFAHRIENESEQEMTSKNRMGFIGRAFAVLGAAT
                     AAAAAVEGHRRPKAQDLRTLGIDPASFPGNRHG"
     gene            complement(742765..744282)
                     /locus_tag="Smed_4255"
                     /db_xref="GeneID:5318468"
     CDS             complement(742765..744282)
                     /locus_tag="Smed_4255"
                     /note="PFAM: protein of unknown function DUF112
                     transmembrane;
                     KEGG: sme:SMb20726 conserved hypothetical membrane
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312993.1"
                     /db_xref="GI:150376397"
                     /db_xref="InterPro:IPR002823"
                     /db_xref="GeneID:5318468"
                     /translation="MGTFDFLLQGLLVAAQPMNLLYALIGVTLGTAVGVLPGIGPALT
                     VALLLPVTYQLDPAGSLIMFAGIYYGGMYGGSTTSILLNTPGESASIVTALEGNKMAR
                     AGRGGPALATAAIGSFVAGLIATLGLAFIAPYIVKLALVFGPREYFALMVLAFVTVSS
                     AFGDSTLRGLTSLFVGLTLACIGIDQLTGQARLSFGVPDLLDGIEVTTLAVAMFAIGE
                     TLFIAAQGDRGPDKVEAVKGSVWMNAADWGRSWKPWLRGTFIGFPIGAMPAGGAEIGT
                     FLSYAAEKRLTKHPEEFGNGAIEGVAGPEAANNASAAGTLVPLLTLGLPTTATAAIML
                     AGFQQYGLQPGPLLFATNPQLVWGLIASLLIANFMLLVLNLPLIGLWVKLLTIPKPWL
                     YAGILLFATLGTIGANPSVFELGMLLAFGLLGYVMRIFGYPIAPVVVGLILGPLAEQQ
                     LRRALSISQGDVTVLFTSPLAAVLLVIAALALIVPLILRARGRGEMLAQLAASED"
     misc_feature    complement(742771..744282)
                     /locus_tag="Smed_4255"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3333"
                     /db_xref="CDD:225870"
     gene            complement(744297..744788)
                     /locus_tag="Smed_4256"
                     /db_xref="GeneID:5318469"
     CDS             complement(744297..744788)
                     /locus_tag="Smed_4256"
                     /note="KEGG: sme:SMb20725 putative tricarboxylic transport
                     membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative tricarboxylic transport membrane
                     protein"
                     /protein_id="YP_001312994.1"
                     /db_xref="GI:150376398"
                     /db_xref="GeneID:5318469"
                     /translation="MNKGNNPSVETRRPDRAALIIAVVLAAIAAVIFWDVSRLTGLAG
                     YSQVGPMTVPYAIACCLIALAVWTAIEAWRGDFPEREHQQAGPVVWIVAGLAAQMLLL
                     NTLGFSIATGILFALTARGFGKRRLWLTVPVGIAFSFAVWAVFAKLLQLSLPAGPLER
                     LFF"
     misc_feature    complement(744327..744692)
                     /locus_tag="Smed_4256"
                     /note="Tripartite tricarboxylate transporter TctB family;
                     Region: TctB; pfam07331"
                     /db_xref="CDD:219375"
     gene            complement(744785..745729)
                     /locus_tag="Smed_4257"
                     /db_xref="GeneID:5318470"
     CDS             complement(744785..745729)
                     /locus_tag="Smed_4257"
                     /note="PFAM: Uncharacterized protein UPF0065;
                     KEGG: sme:SMb20724 putative tricarboxylic transport
                     membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001312995.1"
                     /db_xref="GI:150376399"
                     /db_xref="InterPro:IPR005064"
                     /db_xref="GeneID:5318470"
                     /translation="MKHVFLASILAGALALPVYAADYTIIAPANPGGGWDQTARSMQT
                     VMQQEGISGNVQVQNVPGAGGTIGLAQFASQQKGNPNALLVGGYVMVGAILTNNSPVS
                     LKDVTPIARLTGEYEAIVVPASSEIQTMKDLVEALKKDPGAVSWAGGSAGGTDHIAVG
                     LIAKAAGVDPTKINYIAYSGGGEALAAILGSQVTAGISGYGEFESQVKAGTLRLLAVS
                     SAERIEGIDAPTLKESGVDVVVENWRMVAAAPGLTDEQKTAVEADVEKLAKSAGWQEV
                     LKTKGWQDTYLAGDAFEEQLAKDISATETVLKDIGLVK"
     misc_feature    complement(744788..745729)
                     /locus_tag="Smed_4257"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3181"
                     /db_xref="CDD:225722"
     sig_peptide     complement(745667..745729)
                     /locus_tag="Smed_4257"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 21"
     gene            complement(745965..747065)
                     /locus_tag="Smed_4258"
                     /db_xref="GeneID:5318471"
     CDS             complement(745965..747065)
                     /locus_tag="Smed_4258"
                     /note="KEGG: sme:SMb20723 putative iron ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="putative iron ABC transporter periplasmic
                     solute-binding protein"
                     /protein_id="YP_001312996.1"
                     /db_xref="GI:150376400"
                     /db_xref="InterPro:IPR011587"
                     /db_xref="GeneID:5318471"
                     /translation="MNGSTLRHCGFMRFLISLGFLILSAALAKAAPAFFPAPSGDPAA
                     PVLTVYSSLDEPLARPMIKGFQSANPDVAVRYDDMLTGEIYDRIVRETDAGEKTADFA
                     FSSAMDLQVKLSNDGYAQRSDLPMTGRWPAWANWRNTAYALTFEPAVFVYHKPSFRNE
                     RPPATRAEFVDYLKRKGNAVFGRIGTYDIERSGVGFLFMSRDQEQFGDIWTVIRTMGA
                     AGVKLYSTSQAILERISDGRFVLGYNILGSYAADWASRHPDVGIVLPKDYTVVMSRIG
                     LVPQAAAEPELGRRYLQFFMSKEGQTIMARELQIPAVSPEVAGENTANTMREMLGGQL
                     KPVPVSPGLMVYLDQVKRARLIARWNETLRSQ"
     sig_peptide     complement(746973..747065)
                     /locus_tag="Smed_4258"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.998) with cleavage site probability 0.728 at
                     residue 31"
     misc_feature    complement(745983..746885)
                     /locus_tag="Smed_4258"
                     /note="ABC-type Fe3+ transport system, periplasmic
                     component [Inorganic ion transport and metabolism];
                     Region: AfuA; COG1840"
                     /db_xref="CDD:224753"
     misc_feature    complement(746112..746885)
                     /locus_tag="Smed_4258"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_8; pfam13416"
                     /db_xref="CDD:222114"
     gene            747110..747787
                     /locus_tag="Smed_4259"
                     /db_xref="GeneID:5319010"
     CDS             747110..747787
                     /locus_tag="Smed_4259"
                     /note="PFAM: response regulator receiver; transcriptional
                     regulator domain protein;
                     KEGG: sme:SMb20722 putative two-component response
                     regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="two component transcriptional regulator"
                     /protein_id="YP_001312997.1"
                     /db_xref="GI:150376401"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR001867"
                     /db_xref="GeneID:5319010"
                     /translation="MRILLVEDNRALAEGLSTLLRGSGYAVDVVSDGASAHAVAAAES
                     FDLVILDLNLPEMDGLDVLRAMRARQNRAAVLILTARGAPEERVKGLDLGADDYLIKP
                     FDIGEFEARVRVLLRRQAGLRASVVSYGEVSLDLTTRSFSSAGMPIEIPARELGLLEL
                     LFMRAGKVVAKDAIVQSLTDLDDDLSPNAIEQYVSRLRKRLSPYGLTVRTARGIGYYL
                     DKTADPE"
     misc_feature    747110..747766
                     /locus_tag="Smed_4259"
                     /note="Response regulators consisting of a CheY-like
                     receiver domain and a winged-helix DNA-binding domain
                     [Signal transduction mechanisms / Transcription]; Region:
                     OmpR; COG0745"
                     /db_xref="CDD:223816"
     misc_feature    747119..747457
                     /locus_tag="Smed_4259"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    order(747128..747133,747260..747262,747284..747286,
                     747344..747346,747401..747403,747410..747415)
                     /locus_tag="Smed_4259"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    747260..747262
                     /locus_tag="Smed_4259"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    order(747269..747274,747278..747286)
                     /locus_tag="Smed_4259"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    747410..747418
                     /locus_tag="Smed_4259"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    747488..747763
                     /locus_tag="Smed_4259"
                     /note="Effector domain of response regulator. Bacteria and
                     certain eukaryotes like protozoa and higher plants use
                     two-component signal transduction systems to detect and
                     respond to changes in the environment. The system consists
                     of a sensor histidine kinase and...; Region: trans_reg_C;
                     cd00383"
                     /db_xref="CDD:238225"
     misc_feature    order(747560..747562,747617..747622,747674..747676,
                     747683..747685,747707..747712,747737..747739,
                     747752..747754)
                     /locus_tag="Smed_4259"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238225"
     gene            747784..749178
                     /locus_tag="Smed_4260"
                     /db_xref="GeneID:5319011"
     CDS             747784..749178
                     /locus_tag="Smed_4260"
                     /note="PFAM: ATP-binding region ATPase domain protein;
                     histidine kinase HAMP region domain protein; histidine
                     kinase A domain protein; Two-component sensor kinase
                     domain protein;
                     KEGG: sme:SMb20721 putative two-component sensor histidine
                     kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane sensor signal transduction
                     histidine kinase"
                     /protein_id="YP_001312998.1"
                     /db_xref="GI:150376402"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003660"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="InterPro:IPR013727"
                     /db_xref="GeneID:5319011"
                     /translation="MNVSGIRKGVYSLRRRLLGWLLISTAVIGVVALADTYREAVKTA
                     NAVSDRVLAGSALAIAERVVVAEDGSLEVDIPYVALEMLTSAAQDRVFYRVDGPPGAF
                     ITGYQTLPSLSENTGQSTSFADAVFRGEPIRVAELRRSASTGVNSVPFVVTVAETTIA
                     RRRLARTILIRSALRLALMIAGAAIIVWVAVTFSLRPLYRLGDAIAERSPDDLHPIRE
                     RVPNEVQGLVDTVNSFMVRLQSALDALRHFTGNASHQLRTPLAIIRTQLALAQRATTI
                     EETRAAAMRADEAVADAERILAQLLLMAKIDAAGRNEARGLERVDLAGLARTVTADHV
                     PAAGEAGIDLGFAGEGEHWVRAEPLLVGELLKNLIGNALLYAGRGAEVTVRVGSCDHS
                     VLLEVEDNGPGIPPDMREAALKRFRRGGEEAPGTGLGLPIVEEIAELYGGRMRLEEGE
                     GGLGLKVEVMFPAG"
     sig_peptide     747784..747888
                     /locus_tag="Smed_4260"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.994) with cleavage site probability 0.983 at
                     residue 35"
     misc_feature    747859..748251
                     /locus_tag="Smed_4260"
                     /note="Two-component sensor kinase N-terminal; Region:
                     2CSK_N; pfam08521"
                     /db_xref="CDD:219880"
     misc_feature    748360..749094
                     /locus_tag="Smed_4260"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: BaeS; COG0642"
                     /db_xref="CDD:223715"
     misc_feature    748507..>748590
                     /locus_tag="Smed_4260"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    order(748525..748527,748537..748539,748549..748551,
                     748558..748560,748570..748572,748579..748581)
                     /locus_tag="Smed_4260"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    748543..748545
                     /locus_tag="Smed_4260"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    748873..>749094
                     /locus_tag="Smed_4260"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    order(748882..748884,748894..748896,748903..748905,
                     748972..748974,748978..748980,748984..748986,
                     748990..748995,749062..749073)
                     /locus_tag="Smed_4260"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    748894..748896
                     /locus_tag="Smed_4260"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    order(748984..748986,748990..748992,749062..749064,
                     749068..749070)
                     /locus_tag="Smed_4260"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            complement(749275..750225)
                     /locus_tag="Smed_4261"
                     /db_xref="GeneID:5319012"
     CDS             complement(749275..750225)
                     /locus_tag="Smed_4261"
                     /note="KEGG: sme:SMb20720 putative sugar uptake ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sugar uptake ABC transporter
                     periplasmic solute-binding protein"
                     /protein_id="YP_001312999.1"
                     /db_xref="GI:150376403"
                     /db_xref="GeneID:5319012"
                     /translation="MRKGLMGIAAIAMMALTGAAHAQEKKVTIGVSIPAADHGWTAGV
                     VFHAERVAKLLMEQHPGLNVIVKTSPDPASQANAVQDLETQGIDALVILPTDPDPLVN
                     AIKEVKSNGKFVALVDRAPSVNDSSVRDLYVAGNNPALGQVAGEYIKATTPDAKVVVI
                     RGLPIPIDQQRQDGFDKGIEGSNVEILDRQYGNWNRDDAFKVMQDYLTKYPQIDVVWC
                     QDDDMAVGVLQAIDQAKRTDIQYVVAGAGSKDMIKKVMDGDKMIPVDVLYPPAMVGTA
                     LEMTVANFYGQVPVRGVYTIDATLVTKENAKDFYFPDSPF"
     sig_peptide     complement(750157..750225)
                     /locus_tag="Smed_4261"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 23"
     misc_feature    complement(749278..750159)
                     /locus_tag="Smed_4261"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     RbsB; COG1879"
                     /db_xref="CDD:224791"
     misc_feature    complement(749323..750144)
                     /locus_tag="Smed_4261"
                     /note="Periplasmic sugar-binding domain of uncharacterized
                     ABC-type transport systems; Region:
                     PBP1_ABC_sugar_binding_like_3; cd06311"
                     /db_xref="CDD:107306"
     misc_feature    complement(order(749425..749427,749488..749490,
                     749713..749715,749872..749874,750106..750108))
                     /locus_tag="Smed_4261"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107306"
     gene            complement(750293..751303)
                     /locus_tag="Smed_4262"
                     /db_xref="GeneID:5319013"
     CDS             complement(750293..751303)
                     /locus_tag="Smed_4262"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20719 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001313000.1"
                     /db_xref="GI:150376404"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5319013"
                     /translation="MSVNEESIQSTTHRRTWRDVDLRAVAPFAALALLLIVGALVNPN
                     FISLNNLANVATRSAFIAIIAVGATFVISAGDLDLSVGSMVAFVASLMIIFMNSGVIA
                     DPALMLTAAIVFAVAVGGACGLANGLITTVGRIEPFIATLGTMGIYRGLTTWLSQGGA
                     ITLREPEIQELYRPAYFGSIFGVPVPIAIILAVTAVAAFILYRTRYGRHVVAVGSNSD
                     VARYSGIAVNRVRTIAFVIQGLCVAVAVLLYVPRLGSTSATTGILWELQAITAVVVGG
                     TALKGGAGRVWGTICGAFILELVGNIMLLSNFISEYLIGAMQGAIIIIAMLVQRSLVR
                     KS"
     misc_feature    complement(750392..751156)
                     /locus_tag="Smed_4262"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(750368..751132)
                     /locus_tag="Smed_4262"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(750596..750652)
                     /locus_tag="Smed_4262"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(751380..752906)
                     /locus_tag="Smed_4263"
                     /db_xref="GeneID:5319014"
     CDS             complement(751380..752906)
                     /locus_tag="Smed_4263"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20718 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313001.1"
                     /db_xref="GI:150376405"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319014"
                     /translation="MDPEAVDAARVVLEARRISKSFSGVQVLFSVNFELRAGEIHALM
                     GENGAGKSTLVKILSGFEQPSSGEVLLDGERVTFPANGAAEALGIVIIHQEFNLAEHL
                     TVAESLFLGREVTRFGMLDRKYMRAETRRVLDLLGCNVDANALIGSLSIAEKQMVEIA
                     KAISRDARIVFMDEPTAVLSREETSFLFRQVRKLRDRGTSFVFVSHKLDEVIELTDRV
                     TVLRDGQWVKTAPTSMLDGESIAQLMVGREMSSLYPAKNEPDVDEEVVLRVDALSTDY
                     VKDASFEVRRGEILGFSGMIGSGRTELMEAVAGLRHRLSGEVAIRGESVPSGDVHAAN
                     RCGLAYMTKDRKAKGLLLNSGMTANLTLQSLGRHARIGYLSPASEAAALERARRRFDI
                     RVRDGNVVARRMSGGNQQKLLLAKVMETEPDIIIIDEPTRGIDVGTKQQIYHFISALA
                     RDGSSIIVVSSEMPEVIGLCTRVAVMREGRIVGMLEGDEISEQEIMRYAAGLKKMAAA
                     "
     misc_feature    complement(751404..752894)
                     /locus_tag="Smed_4263"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    complement(752220..752870)
                     /locus_tag="Smed_4263"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    complement(752751..752774)
                     /locus_tag="Smed_4263"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(752289..752291,752385..752390,
                     752625..752627,752748..752756,752760..752765))
                     /locus_tag="Smed_4263"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(752625..752636)
                     /locus_tag="Smed_4263"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(752433..752450,752592..752603))
                     /locus_tag="Smed_4263"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(752385..752402)
                     /locus_tag="Smed_4263"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(752367..752378)
                     /locus_tag="Smed_4263"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(752283..752303)
                     /locus_tag="Smed_4263"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(751464..752117)
                     /locus_tag="Smed_4263"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            753175..754206
                     /locus_tag="Smed_4264"
                     /db_xref="GeneID:5319015"
     CDS             753175..754206
                     /locus_tag="Smed_4264"
                     /EC_number="5.1.1.1"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: sme:SMb20717 putative transcriptional regulator,
                     LacI family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="YP_001313002.1"
                     /db_xref="GI:150376406"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5319015"
                     /translation="MSDSTPATIEDVARIAEVSIATVSRAIHTPEKVAKSTRLKVNQA
                     IAITGYTTNAMARSLRLGRSNMILVVAPDIGDPNFSSILVGLENEARSHGYGVLIGHT
                     QNDAQRAVEYLKFLNSNQAAGLILFTGILPFGHETIAARLPPSVGIFEPVFNGGIPYV
                     GVDDEEGARKVVDLLLAEGHRKIAFIGDSRTRLAYKRRRAGYDAGLNSAGVPAELRLV
                     QEGDGTLESGRAAVERLFVRDTLPTAFMCVNDQTALGVMIGLKARGYDIPRDFSVTGF
                     DDVPQATFMTPALTTIRQPRTLIGKHAMALLLELLSNGLPAEMEILLRPDLVVRNSVS
                     TPSPRWRER"
     misc_feature    753193..754182
                     /locus_tag="Smed_4264"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    753205..753354
                     /locus_tag="Smed_4264"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(753226..753240,753244..753249,753256..753258,
                     753271..753276,753283..753285,753322..753324,
                     753331..753333,753340..753345,753349..753354)
                     /locus_tag="Smed_4264"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    753322..753351
                     /locus_tag="Smed_4264"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    753370..754170
                     /locus_tag="Smed_4264"
                     /note="Ligand-binding domain of an uncharacterized
                     transcription regulator from Actinobacillus succinogenes
                     and its close homologs from other bacteria; Region:
                     PBP1_LacI_like_6; cd06284"
                     /db_xref="CDD:107279"
     misc_feature    order(753370..753372,753433..753435,753460..753462,
                     753469..753471,753475..753477,753532..753534,
                     753847..753849,753946..753948)
                     /locus_tag="Smed_4264"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107279"
     misc_feature    order(753400..753402,753766..753768,754003..754005,
                     754054..754056)
                     /locus_tag="Smed_4264"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107279"
     gene            complement(754241..754465)
                     /locus_tag="Smed_4265"
                     /db_xref="GeneID:5319016"
     CDS             complement(754241..754465)
                     /locus_tag="Smed_4265"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313003.1"
                     /db_xref="GI:150376407"
                     /db_xref="GeneID:5319016"
                     /translation="MLVLQCSPYDYGLALASQIDYVTDMQNHRRIIMPSQRQLAKRAE
                     PGFMLQLWNAMLGVQTRGAASLFSSRTRSF"
     gene            complement(754573..755598)
                     /locus_tag="Smed_4266"
                     /db_xref="GeneID:5319017"
     CDS             complement(754573..755598)
                     /locus_tag="Smed_4266"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20714 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001313004.1"
                     /db_xref="GI:150376408"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5319017"
                     /translation="MNSNVAAQGTNSPLVRSRRRMPPELSIFLVLIGIALVYEILGWL
                     FVGQSFLMNTQRLTIMILQVSVIGIIAVGVTQVIITGGIDLSSGSVVGMTAMISASVA
                     QASTWPRALYPSLTDLPAIIPIGLGVGIGLLAGFINGQLIARTKIPPFIATLGMMVSA
                     RGVSKWYTKGQPVSGLTEQFNFIGTGIWPVIVFLVVALIFHIALRYTRYGKFTYAIGA
                     NVQAARVSGINVEAHLVKVYAIAGMLAGLAGVVTAARAQTAQAGMGVMYELDAIAATV
                     IGGTSLTGGVGRITGTVIGTVILGVMTSGFTFLRVDAYYQEIVKGIIIVAAVVVDVYR
                     QKSRKKA"
     misc_feature    complement(754759..755418)
                     /locus_tag="Smed_4266"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(754651..755409)
                     /locus_tag="Smed_4266"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(754882..754938)
                     /locus_tag="Smed_4266"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(755696..757237)
                     /locus_tag="Smed_4267"
                     /db_xref="GeneID:5319018"
     CDS             complement(755696..757237)
                     /locus_tag="Smed_4267"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20713 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313005.1"
                     /db_xref="GI:150376409"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319018"
                     /translation="MTLSPTTMAAVRASGAVPQSEYLLTAEGIRKEFPGVVALDDVEF
                     KLKRGTVHALMGENGAGKSTLMKILAGIYHPDRGEVKLRGAGIRLKSPLDALENGIAM
                     IHQELNLMPFMTVAENIWIRREPKNRFGLVDHGEMRRMTAKLFERLKIDLDPEIEVRH
                     LSVANRQMVEIAKAVSYESDVLIMDEPTSALTEREVAHLFEIIRDLRSQGIGIVYITH
                     KMNELFEIADEFSVFRDGKYIGTHLSNEVTRDDIIRMMVGREITQMFPKEDVPIGDVV
                     LSVKNLTLNGVFHDVTFDVRAGEILGVAGLVGSGRSNVAETLFGVTPASSGTIAIDGN
                     KVVIDSANTAIRHRMAFLTEDRKDTGCLLILNILENMQIAVLQDKFVRGGFVSEKEVA
                     AACEDMSRKLRVKTPNLYERIENLSGGNQQKVLIGRWLLTNPRILILDEPTRGIDVGA
                     KAEIHRLVTELARNGVAVIMISSEMPEVLGMSDRIMVMHEGRVTGILDRADATQIKVM
                     ELAAR"
     misc_feature    complement(755699..757192)
                     /locus_tag="Smed_4267"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    complement(756515..757168)
                     /locus_tag="Smed_4267"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    complement(757049..757072)
                     /locus_tag="Smed_4267"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(756584..756586,756680..756685,
                     756923..756925,757046..757054,757058..757063))
                     /locus_tag="Smed_4267"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(756923..756934)
                     /locus_tag="Smed_4267"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(756728..756742,756887..756901))
                     /locus_tag="Smed_4267"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(756680..756697)
                     /locus_tag="Smed_4267"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(756662..756673)
                     /locus_tag="Smed_4267"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(756578..756598)
                     /locus_tag="Smed_4267"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(755759..756421)
                     /locus_tag="Smed_4267"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            complement(757423..758352)
                     /locus_tag="Smed_4268"
                     /db_xref="GeneID:5319019"
     CDS             complement(757423..758352)
                     /locus_tag="Smed_4268"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     KEGG: sme:SMb20712 putative rhizopine uptake ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313006.1"
                     /db_xref="GI:150376410"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5319019"
                     /translation="MKKFFAGTALAVLMSTAAHAETIGVSMALFDDNFLTVLRSGMQD
                     YAKTLDGVELQVEDAQNDVSKQQSQIQNFIAAGVDAIIVNPVDTDATTVMSKIAADAG
                     IPLVYVNREPVNVDTLPEKQAFVASNEQESGTLQTKEICKMLGGKGKAVVMMGELSNQ
                     AARMRTKDIHDVVATDECKGIEIVEEQTANWSRTQGADLMTNWLSAGLEFDAVISNND
                     EMAIGAIQALKAAGRSMDSVVIGGIDATQDALAAMAAGDLDVTVFQNAAGQGKGSVDA
                     ALKLAKGEPVEKKVYIPFELVTKENLEQYQAKN"
     sig_peptide     complement(758290..758352)
                     /locus_tag="Smed_4268"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 21"
     misc_feature    complement(757426..758343)
                     /locus_tag="Smed_4268"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     RbsB; COG1879"
                     /db_xref="CDD:224791"
     misc_feature    complement(757459..758289)
                     /locus_tag="Smed_4268"
                     /note="Periplasmic binding proteins specific to
                     rhizopines; Region: PBP1_rhizopine_binding_like; cd06301"
                     /db_xref="CDD:107296"
     misc_feature    complement(order(757561..757563,757621..757623,
                     757858..757860,758026..758028,758251..758253))
                     /locus_tag="Smed_4268"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107296"
     gene            complement(758589..759404)
                     /locus_tag="Smed_4269"
                     /db_xref="GeneID:5319031"
     CDS             complement(758589..759404)
                     /locus_tag="Smed_4269"
                     /note="PFAM: Xylose isomerase domain protein TIM barrel;
                     KEGG: sme:SMb20711 putative Ioli protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase domain-containing protein"
                     /protein_id="YP_001313007.1"
                     /db_xref="GI:150376411"
                     /db_xref="InterPro:IPR012307"
                     /db_xref="GeneID:5319031"
                     /translation="MTAALPFALNHMAAPALPLDAFFALAASLGISMVEIRNDIAGNA
                     ILDGTNSQQVKALAEKYGLTIISINALQRFNEWNETRADEAHELISYARNCGAKALVL
                     VPVNDGSGKEDRVRQANLRQALSALKPMLDTAAIAGLVEPLGFEVCSLRSKAEAADAI
                     REISGDGTFRLVHDTFHHHLSGEDRFLADMTGLVHISGVADGNLAVADMRDPDRVLIG
                     TGDRLDNEGQIRRLRAEGYAGPLSFEPFAPSVHELADPANALRESMNYLRVRS"
     misc_feature    complement(758592..759404)
                     /locus_tag="Smed_4269"
                     /note="Predicted sugar epimerase [Carbohydrate transport
                     and metabolism]; Region: COG4130"
                     /db_xref="CDD:226615"
     sig_peptide     complement(759324..759404)
                     /locus_tag="Smed_4269"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.634) with cleavage site probability 0.633 at
                     residue 27"
     gene            complement(759595..760482)
                     /locus_tag="Smed_4270"
                     /db_xref="GeneID:5319032"
     CDS             complement(759595..760482)
                     /locus_tag="Smed_4270"
                     /EC_number="1.1.1.31"
                     /note="PFAM: 6-phosphogluconate dehydrogenase NAD-binding;
                     KEGG: sme:SMb20710 putative dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="YP_001313008.1"
                     /db_xref="GI:150376412"
                     /db_xref="InterPro:IPR002204"
                     /db_xref="InterPro:IPR006115"
                     /db_xref="InterPro:IPR006183"
                     /db_xref="GeneID:5319032"
                     /translation="MTRSNIGFIGLGLMGQGMAANILKKGWPLFVMAHRNRAPVEALV
                     AEGAKEAKSPREMAEHCDIIVLCVTGSPEVLSVMGGPDGIASAGRPVTIIDCSTSDPS
                     VTTKLAADVAESGLTLIDAPLSRTPADAAAGTLDVMVGGAENDVQRIWPVLECFAGRI
                     IHTGPTGSGHTMKLLNNFVSMGYAALYSEALMLGRKAGLTPEVFDSVIRGGRMDCPFY
                     QTFFRWVLERDPNAHKFAIRNAFKDMSYLAGYANAAGIANPIGAAVRNSFAQAVGAGR
                     GEDYVPMLSDFIAKSNGLE"
     sig_peptide     complement(760423..760482)
                     /locus_tag="Smed_4270"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.962) with cleavage site probability 0.959 at
                     residue 20"
     misc_feature    complement(759616..760467)
                     /locus_tag="Smed_4270"
                     /note="3-hydroxyisobutyrate dehydrogenase and related
                     beta-hydroxyacid dehydrogenases [Lipid metabolism];
                     Region: MmsB; COG2084"
                     /db_xref="CDD:224995"
     misc_feature    complement(<759841..760467)
                     /locus_tag="Smed_4270"
                     /note="6-phosphogluconate dehydrogenase-like protein;
                     Reviewed; Region: PRK09599"
                     /db_xref="CDD:236582"
     gene            complement(760529..761086)
                     /locus_tag="Smed_4271"
                     /db_xref="GeneID:5319033"
     CDS             complement(760529..761086)
                     /locus_tag="Smed_4271"
                     /note="responsible for recognizing base lesions in the
                     genome and initiating base excision DNA repair"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyladenine DNA glycosylase"
                     /protein_id="YP_001313009.1"
                     /db_xref="GI:150376413"
                     /db_xref="InterPro:IPR003180"
                     /db_xref="GeneID:5319033"
                     /translation="MYRLNSDVEFFARSAVEVAADLIGSDFTVSGVGGVIVETEAYLP
                     DDAASHSFAGTTARNRAMFGPPAHAYIYLSYGLHWCLNFVCLPGSAVLIRAIEPKWGI
                     ETMRARRGVREDRLLCSGPGRVGQALAINREQDGLPLGRDPFRLTLPATKPPVVTGPR
                     VGITKAVEHPWRFGLARSPFVSRKF"
     misc_feature    complement(760541..761059)
                     /locus_tag="Smed_4271"
                     /note="Alkyladenine DNA glycosylase catalyzes the first
                     step in base excision repair; Region: AAG; cd00540"
                     /db_xref="CDD:187726"
     misc_feature    complement(order(760604..760606,760805..760807,
                     760811..760813,760841..760843,760862..760864,
                     760877..760879,760937..760939,760961..760963,
                     760967..760969))
                     /locus_tag="Smed_4271"
                     /note="active site"
                     /db_xref="CDD:187726"
     misc_feature    complement(order(760601..760606,760691..760693,
                     760718..760729,760772..760774,760805..760807,
                     760811..760813,760841..760843,760853..760855,
                     760862..760864,760871..760873,760910..760912,
                     760916..760918,760922..760924,760937..760939,
                     760943..760945,760961..760963))
                     /locus_tag="Smed_4271"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:187726"
     gene            761297..761848
                     /locus_tag="Smed_4272"
                     /db_xref="GeneID:5319034"
     CDS             761297..761848
                     /locus_tag="Smed_4272"
                     /note="TIGRFAM: methylated-DNA--protein-cysteine
                     methyltransferase;
                     PFAM: Methylated-DNA-[protein]-cysteine
                     S-methyltransferase DNA binding;
                     KEGG: sme:SMb20708 putative
                     methylated-DNA--protein-cysteine methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--protein-cysteine
                     methyltransferase"
                     /protein_id="YP_001313010.1"
                     /db_xref="GI:150376414"
                     /db_xref="InterPro:IPR001497"
                     /db_xref="InterPro:IPR014048"
                     /db_xref="GeneID:5319034"
                     /translation="MHHYHIFETASGCCGIAWSDAGIIRFQLPTRSAESTERLLLRRL
                     QGGVPHEPPPRVAEAIVAVKAYFEGRKTDFSGFELDLEGQDAFFRRVYRAARKIPWGS
                     TTTYGALAKELGAGPEVARDVGQAMAKNPVALIIPCHRVLAAGGKIGGFSAPGGSSTK
                     LRMLEMEGVAVAPPEPAQQSLGF"
     misc_feature    761297..761803
                     /locus_tag="Smed_4272"
                     /note="Methylated DNA-protein cysteine methyltransferase
                     [DNA replication, recombination, and repair]; Region: Ada;
                     COG0350"
                     /db_xref="CDD:223427"
     misc_feature    761555..761800
                     /locus_tag="Smed_4272"
                     /note="The DNA repair protein O6-alkylguanine-DNA
                     alkyltransferase (ATase; also known as AGT, AGAT and MGMT)
                     reverses O6-alkylation DNA damage by transferring O6-alkyl
                     adducts to an active site cysteine irreversibly, without
                     inducing DNA strand breaks. ATases...; Region: ATase;
                     cd06445"
                     /db_xref="CDD:119438"
     misc_feature    order(761555..761560,761612..761617,761639..761641,
                     761651..761653,761657..761662,761666..761668,
                     761675..761680,761684..761686,761708..761710,
                     761723..761725,761744..761746)
                     /locus_tag="Smed_4272"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:119438"
     misc_feature    order(761612..761614,761708..761713,761717..761719,
                     761795..761797)
                     /locus_tag="Smed_4272"
                     /note="active site"
                     /db_xref="CDD:119438"
     gene            761850..763115
                     /locus_tag="Smed_4273"
                     /db_xref="GeneID:5319035"
     CDS             761850..763115
                     /locus_tag="Smed_4273"
                     /note="PFAM: adenylyl cyclase class-3/4/guanylyl cyclase;
                     KEGG: sme:SMb20707 putative adenylate cyclase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenylate/guanylate cyclase"
                     /protein_id="YP_001313011.1"
                     /db_xref="GI:150376415"
                     /db_xref="InterPro:IPR001054"
                     /db_xref="GeneID:5319035"
                     /translation="MTITKPGEADIALQSPTEPPSNLPDGSEGIWPARRRRIIDWLVI
                     ETRGERFIDNIFVELCNRLVEAGVPVARATLHFRIHHPQWLGARILWRKGLSEAELDT
                     YAYGVEDSIEYLNSPLREFNEGAEEVRGHLDDPPASGKAYPLYDELRAEGLTDYLIWP
                     LYHTLGKRHAITFASDRPGGFGPDDLIFLKDILPALALVSEIRLKNRFARTLLETYVG
                     PHASEQILAGATTRGSGVTVGAAILICDLRDFTKLSDLWPRDDVIELLNGYFDAMSEP
                     IERHGGEILKFMGDGLLAIFPLSNPCACSQLLGAIDEAQAALAVLNEENLRKGHDPLG
                     YGIGVHVGDVMYGNIGSRRRLDFTVIGPAVNIASRLETLTKELKRPVLLSKAFVEKAG
                     CAGQLENLGSYVLRGLDEPVDVFAFSGRR"
     misc_feature    762432..763109
                     /locus_tag="Smed_4273"
                     /note="Adenylate cyclase, family 3 (some proteins contain
                     HAMP domain) [Signal transduction mechanisms]; Region:
                     CyaA; COG2114"
                     /db_xref="CDD:225025"
     misc_feature    762567..763097
                     /locus_tag="Smed_4273"
                     /note="cyclase homology domain; Region: CHD; cd07302"
                     /db_xref="CDD:143636"
     misc_feature    order(762579..762581,762585..762602,762705..762707,
                     762711..762719,762726..762728,762921..762929,
                     762939..762944,762951..762956,763065..763067)
                     /locus_tag="Smed_4273"
                     /note="nucleotidyl binding site; other site"
                     /db_xref="CDD:143636"
     misc_feature    order(762585..762587,762717..762719)
                     /locus_tag="Smed_4273"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143636"
     misc_feature    order(762600..762602,762636..762638,762645..762650,
                     762657..762659,762669..762671,762705..762710,
                     762882..762884,762891..762893,762924..762935,
                     762942..762944,763065..763067)
                     /locus_tag="Smed_4273"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143636"
     gene            complement(763297..764073)
                     /locus_tag="Smed_4274"
                     /db_xref="GeneID:5319036"
     CDS             complement(763297..764073)
                     /locus_tag="Smed_4274"
                     /note="PFAM: extracellular solute-binding protein family
                     3;
                     KEGG: sme:SMb20706 putative amino acid uptake ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313012.1"
                     /db_xref="GI:150376416"
                     /db_xref="InterPro:IPR001638"
                     /db_xref="GeneID:5319036"
                     /translation="MRSLILALALAACALTSSATAAEKLRIGTEGAYPPFNFVDSTGK
                     IGGFDVEIGLALCERMKIECEVVAQDWDGIIPGLLASKYDMIIASMFITEDRKKQVAF
                     TDPYYLAAMTHAAPKGAGITDFSNEALKGKVIGAQSGTTQADYIAAVYPDAEIKLYPT
                     QDEANLDMVNGRLDLQVGDMLPLLDWVTKNDDGKGCCELIGEPITDKKFVGDGVGIAV
                     RQEDNELREKLNKALDQIRTDGTYKKINDKYFTIDVYTMK"
     sig_peptide     complement(764008..764073)
                     /locus_tag="Smed_4274"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.992 at
                     residue 22"
     misc_feature    complement(763324..764007)
                     /locus_tag="Smed_4274"
                     /note="lysine-arginine-ornithine-binding periplasmic
                     protein; Region: 3A0103s03R; TIGR01096"
                     /db_xref="CDD:233269"
     misc_feature    complement(763324..764001)
                     /locus_tag="Smed_4274"
                     /note="Bacterial periplasmic transport systems use
                     membrane-bound complexes and substrate-bound,
                     membrane-associated, periplasmic binding proteins (PBPs)
                     to transport a wide variety of  substrates, such as, amino
                     acids, peptides, sugars, vitamins and inorganic...;
                     Region: PBPb; cd00134"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(763537..763539,763651..763653,
                     763786..763788,763861..763863,763975..763977))
                     /locus_tag="Smed_4274"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(763558..763560,763576..763578,
                     763588..763590))
                     /locus_tag="Smed_4274"
                     /note="membrane-bound complex binding site; other site"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(763429..763443,763453..763455))
                     /locus_tag="Smed_4274"
                     /note="hinge residues; other site"
                     /db_xref="CDD:238078"
     gene            complement(764210..765205)
                     /locus_tag="Smed_4275"
                     /db_xref="GeneID:5319037"
     CDS             complement(764210..765205)
                     /locus_tag="Smed_4275"
                     /note="PFAM: protein of unknown function DUF6
                     transmembrane;
                     KEGG: sme:SMb20705 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313013.1"
                     /db_xref="GI:150376417"
                     /db_xref="InterPro:IPR000620"
                     /db_xref="GeneID:5319037"
                     /translation="MDCSARICEWLAENVPAETRSRFEGIEPMAVDSVPGKLSHENGT
                     ARAGVIVMLLGMLMFSVNDVMGKWLVATYSVGQVVLIRSIAAVLLLAPFLWVSGPKKL
                     FTLERPGLQLARVVASTAEVIAFYFAVVYLPLADVMTYWLAAPIYVAAISPLVLKEPV
                     GWRRWTAIAIGFVGVVVALEPSSQAFTLPAVISILGSMAFAFMMISGRSLRGTPDTTL
                     AFWQIAGAAVAGLVWAPFDWTPLKPLDTALLCLLGVVAMVAHVLVNRALKLADAATVA
                     PLQYTLLFWAIFFGWLIFGDTPRLSMVLGAGLIVASGLFIFFREQQLKRQGRLKG"
     misc_feature    complement(764237..765064)
                     /locus_tag="Smed_4275"
                     /note="Permeases of the drug/metabolite transporter (DMT)
                     superfamily [Carbohydrate transport and metabolism / Amino
                     acid transport and metabolism / General function
                     prediction only]; Region: RhaT; COG0697"
                     /db_xref="CDD:223769"
     misc_feature    complement(764711..765037)
                     /locus_tag="Smed_4275"
                     /note="EamA-like transporter family; Region: EamA;
                     pfam00892"
                     /db_xref="CDD:216178"
     misc_feature    complement(764252..764605)
                     /locus_tag="Smed_4275"
                     /note="EamA-like transporter family; Region: EamA;
                     pfam00892"
                     /db_xref="CDD:216178"
     gene            complement(765285..766745)
                     /gene="glgA"
                     /locus_tag="Smed_4276"
                     /db_xref="GeneID:5319038"
     CDS             complement(765285..766745)
                     /gene="glgA"
                     /locus_tag="Smed_4276"
                     /EC_number="2.4.1.21"
                     /note="catalyzes the formation of alpha-1,4-glucan chains
                     from ADP-glucose"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase"
                     /protein_id="YP_001313014.1"
                     /db_xref="GI:150376418"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR011835"
                     /db_xref="InterPro:IPR013534"
                     /db_xref="GeneID:5319038"
                     /translation="MQILSVTAEIFPLAKTGGLADVAGSLPKALQAHGIHTRSFVPGY
                     PGVVRALSEASAITEFDNLFGERATLLAGRAQGLDLFVLDAPGFYNRQGPLYTDTHGR
                     EYADNWKRFAAFSLVGSQIARGLVTNWRPDVIHAHDWHAAMSLLYLKYAGDDSVPRVL
                     TVHNLAFQGQFPAYYFPELGLPAEAYSIDGVEYYGDIGFLKGGLQAADAITVVSPTYA
                     REVMSPAFGMGLEGVMNERHVDVVGIVNGIDLEVWDPSSDPYIEHHYSTRVPLRRLPN
                     RQVLLRQFGLPNTCGPVFASVNRLTWQKGMDLLAATADEIVRNGGTLIVHGQGDEALE
                     AAFMDLMRRYPQNVGVSIGYDERLAHRIHAGADAMLVPSRFEPCGLTQLYALRYGCVP
                     IVSRTGGLSETIIDANDAALHAHVATGIQFTPIDKQGLRLALRRALRLYRLRRVWEGL
                     RRQGMKTDCSWHRSAARYAELYSELLNPDMRLVRSA"
     misc_feature    complement(765315..766745)
                     /gene="glgA"
                     /locus_tag="Smed_4276"
                     /note="glycogen synthase; Provisional; Region: glgA;
                     PRK00654"
                     /db_xref="CDD:234809"
     misc_feature    complement(765324..766742)
                     /gene="glgA"
                     /locus_tag="Smed_4276"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. Glycogen synthase
                     catalyzes the formation and elongation of the
                     alpha-1,4-glucose backbone using ADP-glucose, the second
                     and key step of glycogen biosynthesis. This family...;
                     Region: GT1_Glycogen_synthase_DULL1_like; cd03791"
                     /db_xref="CDD:99965"
     misc_feature    complement(order(765603..765605,765618..765620,
                     765669..765671,765684..765689,765849..765857,
                     766692..766694,766701..766703))
                     /gene="glgA"
                     /locus_tag="Smed_4276"
                     /note="ADP-binding pocket [chemical binding]; other site"
                     /db_xref="CDD:99965"
     misc_feature    complement(order(765450..765452,765534..765536,
                     765540..765545,765558..765560,766089..766091))
                     /gene="glgA"
                     /locus_tag="Smed_4276"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99965"
     gene            767306..767767
                     /locus_tag="Smed_4277"
                     /db_xref="GeneID:5319039"
     CDS             767306..767767
                     /locus_tag="Smed_4277"
                     /note="PFAM: PEBP family protein;
                     KEGG: sme:SMb20703 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="PEBP family protein"
                     /protein_id="YP_001313015.1"
                     /db_xref="GI:150376419"
                     /db_xref="InterPro:IPR005247"
                     /db_xref="InterPro:IPR008914"
                     /db_xref="GeneID:5319039"
                     /translation="MTFSLISPVFADGQPIPQKYTRFGENLFPPLKWTGTPDGTQSFA
                     LIIEDPDAVSGLFRHCGIINIPGHWTELPKAVDTGPERGIKFIKNDFGNARYDGPQPP
                     VGTGVHRYRFRLAALDIANLSIPEDVGAAEAWERACKHLIGEAEIVGTYGS"
     misc_feature    767315..767758
                     /locus_tag="Smed_4277"
                     /note="PhosphatidylEthanolamine-Binding Protein (PEBP)
                     domain present in bacteria and archaea; Region:
                     PEBP_bact_arch; cd00865"
                     /db_xref="CDD:176643"
     misc_feature    order(767450..767455,767474..767476,767480..767482,
                     767597..767611,767621..767623,767627..767629,
                     767633..767635)
                     /locus_tag="Smed_4277"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:176643"
     gene            767954..771037
                     /locus_tag="Smed_4278"
                     /db_xref="GeneID:5319040"
     CDS             767954..771037
                     /locus_tag="Smed_4278"
                     /note="TIGRFAM: PAS sensor protein;
                     PFAM: CheB methylesterase; MCP methyltransferase
                     CheR-type; HWE histidine kinase; PAS fold-4 domain
                     protein; PAS fold domain protein;
                     KEGG: rpa:RPA3316 possible chemotaxis cheB/cheR fusion
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PAS/PAC sensor protein"
                     /protein_id="YP_001313016.1"
                     /db_xref="GI:150376420"
                     /db_xref="InterPro:IPR000014"
                     /db_xref="InterPro:IPR000673"
                     /db_xref="InterPro:IPR000700"
                     /db_xref="InterPro:IPR000780"
                     /db_xref="InterPro:IPR011102"
                     /db_xref="InterPro:IPR013656"
                     /db_xref="InterPro:IPR013767"
                     /db_xref="GeneID:5319040"
                     /translation="MTYEDNRFPIVGIGASAGGIPAMQGFFKGLPVNSNMAFVIVTHL
                     SPEHESQLHEVVARYTDLPVLVAEDGMAAQPNHVYVMPQNAILSIAGGHLRLRKPDAA
                     TRERKPIDIFLSTLAEDQGEQAVGIILSGGDSDGTLGAKAIKEHGGLTLAQASDGSGP
                     RNPDMPQSAISSGVIDLAVTAEEMGEKLIAYANGFMAAQDVATEETPDAREARSEIYG
                     LLRRHSGHDFSGYKSKTFLRRVRRRMQILQVRALPDYLKLLRRDPSEVTNLFRDLLIN
                     VTNFFRDQDAFKALEQLVIPRLFEGRKAGEPVRVWVPGCATGEEVYSLGILMRERMEK
                     LADMPRVQIFATDIDESALGVARAGRYPEALLQGLSPERIARHFNCDGASFVISSDVR
                     ELCIFSPHSVTRDPPFSRMDLVSCRNLLIYLDQETQKRVISTFHYALKPGGYLFLGTS
                     ESIGQHGEHFSTIDKKNRIFQARGHDAVPRVPALVGPPKTVNTADGRIHGLRIGTYPL
                     RQVVEAHVLERFAPAHVVVNADGEAVYYSARTGKYLEVPQGAPSRQILTTARRGLRLD
                     LRAALREAASARKVVVRENALLEDDDDRVQRVNLTVEPLADGAGGEPLYLVVFDPIGP
                     LQSRAEAEHSGYDADTAAILESELRETRERLQSTIEEYETALEELKSSHEELVSVNEE
                     AQSTNEELEASKEEMQSLNEELSTINAELTAKVEELDRANSDLKNLFESMQIATVFLD
                     RNLVIRNFTPAASSFFNIRPSDVGRPLTELSSKLDYPELKEQIASVFKTGEAVEHHLA
                     RDQNGKHFLVRLIPYRDDAARVDGVVVTLVDVTKMAEAEAHQQMLVSELNHRVKNMLA
                     VVISIANHSMQTARSPNEFNQALIGRLQAMGRAYGLLTETHWTAAPVDHLIRQEIEAF
                     GTGRFEVNGPDIHLEPQQGLSIGMVIHELATNASKYGALSKSEGKVLVGWQSANGVFR
                     LTWQESDGPPVSEPEREGFGLSLLKGEIGYRLDGEVETFFRPEGLFVRIAFPFER"
     misc_feature    767981..768526
                     /locus_tag="Smed_4278"
                     /note="CheB methylesterase; Region: CheB_methylest;
                     pfam01339"
                     /db_xref="CDD:216442"
     misc_feature    768593..769378
                     /locus_tag="Smed_4278"
                     /note="Methylase of chemotaxis methyl-accepting proteins
                     [Cell motility and secretion / Signal transduction
                     mechanisms]; Region: CheR; COG1352"
                     /db_xref="CDD:224271"
     misc_feature    768608..768748
                     /locus_tag="Smed_4278"
                     /note="CheR methyltransferase, all-alpha domain; Region:
                     CheR_N; pfam03705"
                     /db_xref="CDD:202731"
     misc_feature    768878..769294
                     /locus_tag="Smed_4278"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    order(768890..768907,768926..768928,768992..768997,
                     769115..769117,769121..769126,769202..769204)
                     /locus_tag="Smed_4278"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     misc_feature    769919..>770146
                     /locus_tag="Smed_4278"
                     /note="Syntaxin N-terminus domain; syntaxins are nervous
                     system-specific proteins implicated in the docking of
                     synaptic vesicles with the presynaptic plasma membrane;
                     they are a family of receptors for intracellular transport
                     vesicles; each target membrane may...; Region: SynN;
                     cl00143"
                     /db_xref="CDD:241634"
     misc_feature    770120..770317
                     /locus_tag="Smed_4278"
                     /note="PAS domain; Region: PAS; smart00091"
                     /db_xref="CDD:214512"
     misc_feature    770126..770392
                     /locus_tag="Smed_4278"
                     /note="PAS domain; Region: PAS_10; pfam13596"
                     /db_xref="CDD:222252"
     misc_feature    770453..771025
                     /locus_tag="Smed_4278"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: COG3920"
                     /db_xref="CDD:226434"
     misc_feature    770489..770728
                     /locus_tag="Smed_4278"
                     /note="HWE histidine kinase; Region: HWE_HK; smart00911"
                     /db_xref="CDD:214907"
     gene            771047..771409
                     /locus_tag="Smed_4279"
                     /db_xref="GeneID:5319115"
     CDS             771047..771409
                     /locus_tag="Smed_4279"
                     /note="PFAM: response regulator receiver;
                     KEGG: ret:RHE_PF00072 probable two-component response
                     regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver protein"
                     /protein_id="YP_001313017.1"
                     /db_xref="GI:150376421"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="GeneID:5319115"
                     /translation="MEVRARILIVEDEWLIAEDHAASLREAGYVVVGPVPSVKQALQA
                     MENQEIDLALLDIQLWKEMSLPLAEHLKAKGVPFAFLSGYSDQKLPPDLSDREVIPKP
                     VDAAFLAEAVARLCKHTG"
     misc_feature    771047..771391
                     /locus_tag="Smed_4279"
                     /note="FOG: CheY-like receiver [Signal transduction
                     mechanisms]; Region: CheY; COG0784"
                     /db_xref="CDD:223855"
     misc_feature    771068..771391
                     /locus_tag="Smed_4279"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    order(771077..771082,771212..771214,771290..771292,
                     771338..771340,771347..771352)
                     /locus_tag="Smed_4279"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    771212..771214
                     /locus_tag="Smed_4279"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    order(771221..771223,771227..771229,771233..771238)
                     /locus_tag="Smed_4279"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    771347..771355
                     /locus_tag="Smed_4279"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     gene            complement(771438..773033)
                     /locus_tag="Smed_4280"
                     /db_xref="GeneID:5319116"
     CDS             complement(771438..773033)
                     /locus_tag="Smed_4280"
                     /note="PFAM: TPR repeat-containing protein;
                     transcriptional regulator domain protein;
                     KEGG: sme:SMb20702 putative regulatory protein, possibly
                     two-component response regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator domain-containing
                     protein"
                     /protein_id="YP_001313018.1"
                     /db_xref="GI:150376422"
                     /db_xref="InterPro:IPR001440"
                     /db_xref="InterPro:IPR001867"
                     /db_xref="InterPro:IPR013026"
                     /db_xref="GeneID:5319116"
                     /translation="MQFMFADYVLDRERRELTLRGQVVSVGPQVFDLLLHLVGTRDRV
                     VSKDELLQAVWGGRIVSESTITSHINAVRKAIGDTGGEQRLVRTVARKGFRFVGDIRI
                     ADSAEARQPGGPGSAGHTSLGSKEPPPALALPDKPSITVLPFQNLSGDADQDYFADGV
                     VEDIITALSRIRWLFVIARNSSFTYKGREVDLKEVGQELGVRYVLEGSVRKAGNRVRI
                     TGQLIDATAGTHLWAERFEGTLDDIFELQDRVAESVVGAIAPQLERAEIERAKRKPTG
                     SLDAYDYYLRGMAHLHNGTREAIEAALPLFYKAIELDPDFASAYAGAAWCYFWRKLNG
                     WMIHRAQEIAEGARLARLAVELGRDDAVALTRSGHALGHLVGDLDGGIALIDRARLLN
                     PNLAPAWFLGGFLRVFRGEPESAIEHIERAARLSPLDQEMFRMQAGTALAHFFAGRFD
                     LASAWAERALGNLPSLLVAVALVAASHALAGRNEEARLAMRRLRALDPSLRVSNLRDW
                     LPIQRQEDFARFADGLRLAGMPE"
     misc_feature    complement(772737..>773030)
                     /locus_tag="Smed_4280"
                     /note="Response regulators consisting of a CheY-like
                     receiver domain and a winged-helix DNA-binding domain
                     [Signal transduction mechanisms / Transcription]; Region:
                     OmpR; COG0745"
                     /db_xref="CDD:223816"
     misc_feature    complement(772746..773021)
                     /locus_tag="Smed_4280"
                     /note="Effector domain of response regulator. Bacteria and
                     certain eukaryotes like protozoa and higher plants use
                     two-component signal transduction systems to detect and
                     respond to changes in the environment. The system consists
                     of a sensor histidine kinase and...; Region: trans_reg_C;
                     cd00383"
                     /db_xref="CDD:238225"
     misc_feature    complement(order(772755..772757,772770..772772,
                     772806..772811,772833..772835,772842..772844,
                     772893..772898,772953..772955))
                     /locus_tag="Smed_4280"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238225"
     misc_feature    complement(772245..772697)
                     /locus_tag="Smed_4280"
                     /note="Predicted integral membrane protein [Function
                     unknown]; Region: COG5616"
                     /db_xref="CDD:227903"
     misc_feature    complement(<772050..772199)
                     /locus_tag="Smed_4280"
                     /note="TPR repeat; Region: TPR_11; pfam13414"
                     /db_xref="CDD:222112"
     misc_feature    complement(771753..772193)
                     /locus_tag="Smed_4280"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cd00189"
                     /db_xref="CDD:238112"
     misc_feature    complement(order(771807..771812,771819..771824,
                     771831..771836,771912..771914,772050..772052,
                     772059..772064,772068..772073,772167..772172,
                     772179..772184,772188..772193))
                     /locus_tag="Smed_4280"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     misc_feature    complement(order(771768..771770,771777..771779,
                     771789..771791,771825..771827,771870..771872,
                     771879..771881,771891..771893,772062..772064,
                     772107..772109,772116..772118,772128..772130,
                     772173..772175))
                     /locus_tag="Smed_4280"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     misc_feature    complement(771753..771959)
                     /locus_tag="Smed_4280"
                     /note="TPR repeat; Region: TPR_11; pfam13414"
                     /db_xref="CDD:222112"
     gene            773358..774110
                     /locus_tag="Smed_4281"
                     /db_xref="GeneID:5319117"
     CDS             773358..774110
                     /locus_tag="Smed_4281"
                     /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase;
                     dTDP-4-dehydrorhamnose reductase; NmrA family protein;
                     KEGG: sme:SMb20701 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NmrA family protein"
                     /protein_id="YP_001313019.1"
                     /db_xref="GI:150376423"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR008030"
                     /db_xref="GeneID:5319117"
                     /translation="MKIVVIGGTGLIGSKLVGNLRERGHDVLAAAPNTGVNTITREGL
                     AEALNGADVVVDVANAPVWEDKAVLDFFETSGRNLLAAEAAAGVRHHIALSIVGSERL
                     PDNGYFRAKVAQENLIKASGIPYTILRATQFFEFVGGIAQSATAGQEIRLSPALIQPI
                     ASDDVAEALADVAVALPVNGTIEIAGPEAIPLDELVRRFLRATEDQRKVLPDVHARYF
                     GAVLDDQSLTPGDNPRIGAIRFEDWLGRQAAG"
     misc_feature    773358..774104
                     /locus_tag="Smed_4281"
                     /note="Predicted nucleoside-diphosphate-sugar epimerases
                     [Cell envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: COG0702"
                     /db_xref="CDD:223774"
     misc_feature    773361..>773762
                     /locus_tag="Smed_4281"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    order(773376..773378,773382..773387,773391..773393,
                     773448..773456,773526..773534,773637..773645,
                     773676..773678,773688..773690,773745..773756)
                     /locus_tag="Smed_4281"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    order(773571..773573,773643..773645,773676..773678,
                     773688..773690)
                     /locus_tag="Smed_4281"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            774189..774602
                     /locus_tag="Smed_4282"
                     /db_xref="GeneID:5319118"
     CDS             774189..774602
                     /locus_tag="Smed_4282"
                     /note="PFAM: Cupin 2 conserved barrel domain protein;
                     KEGG: sme:SMb20700 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cupin 2 domain-containing protein"
                     /protein_id="YP_001313020.1"
                     /db_xref="GI:150376424"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="GeneID:5319118"
                     /translation="MYSRFLSAVALAALSFTTASAGDRPAGKVTVVFDHVLPNVPGKS
                     MRGVLVEYEPGGGSPAHTHPKSAFIYATVLEGAIRSSVNGSPEKVYQVGENFYEDPGS
                     RHEVSVNASDTEPARLLAVFVLDTEEKELTTPIKE"
     sig_peptide     774189..774254
                     /locus_tag="Smed_4282"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.987 at
                     residue 22"
     misc_feature    774270..774596
                     /locus_tag="Smed_4282"
                     /note="Uncharacterized conserved protein, contains
                     double-stranded beta-helix domain [Function unknown];
                     Region: COG1917"
                     /db_xref="CDD:224829"
     gene            774688..775785
                     /locus_tag="Smed_4283"
                     /db_xref="GeneID:5319119"
     CDS             774688..775785
                     /locus_tag="Smed_4283"
                     /note="PFAM: secretion protein HlyD family protein;
                     KEGG: sme:SMb20699 putative protein secretion protein,
                     HlyD family, similar to E. coli EmrK"
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD family protein"
                     /protein_id="YP_001313021.1"
                     /db_xref="GI:150376425"
                     /db_xref="InterPro:IPR006143"
                     /db_xref="GeneID:5319119"
                     /translation="MDSLEDKIAIITDASSANGVATSRSVRRKMIGLVLCLGSVVVVA
                     TGWSWTCENGAMSTDNAYVRGDVTALAPKVAGYVTAVGVEDNQAVRAGDILFRIDDRD
                     YRARLAQAVANVEAAQARLTNVDAEKELQHALIRQAEAQRRSAIAELNLASKAYDRRR
                     ELIRSNTVSQAHVDESDAARSRAEANVLAASATVEAQQQRIAVLAAQREAAVAAVAQA
                     QAARALAEIDLESTVVRAPVGGVIGNRQVRVGRLVASGAPLLDVVPLDNVWIVANFKE
                     TQLEHLRPGQRASITIDGYPNAVLEGVVDSFAPGSGTAFSLLPADNATGNFVRVVQRV
                     PVKIRFAGSPLPGRLVPGLSARVEIDLESGS"
     misc_feature    774856..775764
                     /locus_tag="Smed_4283"
                     /note="efflux pump membrane protein (multidrug resistance
                     protein A); Region: 8a0101; TIGR00998"
                     /db_xref="CDD:233228"
     misc_feature    774883..>774999
                     /locus_tag="Smed_4283"
                     /note="Biotin-lipoyl like; Region: Biotin_lipoyl_2;
                     pfam13533"
                     /db_xref="CDD:205711"
     misc_feature    775384..775734
                     /locus_tag="Smed_4283"
                     /note="HlyD family secretion protein; Region: HlyD_3;
                     pfam13437"
                     /db_xref="CDD:222128"
     gene            775782..777356
                     /locus_tag="Smed_4284"
                     /db_xref="GeneID:5319120"
     CDS             775782..777356
                     /locus_tag="Smed_4284"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: sme:SMb20698 putative transport protein, similar to
                     E. coli multidrug resistance protein EmrB"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001313022.1"
                     /db_xref="GI:150376426"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5319120"
                     /translation="MTIASATPSREISMAGGLLVAGIVLATLTEAIASTVLSLGRGDI
                     IGDTYATPDEFAWLDVGYTTFKLMGFMAASWLMSRFDPRNVIVSSTLAMGMACGIAAM
                     TARLDLLVALRMIQGFSGGILLVGGQAVIFLAFARSRQPILQALFAMGSVVAPATIAP
                     ALQGWLLDSRSWTWIFFSVVPLALAAAGLLLIADRPMPARNVPRPFDWIGFSLISIAL
                     SCFTYVFSQGSRWDWFEEPRILWLSVIGTAAILAFFGQQMLAKGQGLFDFTLFGTEDF
                     CFAFIVSFVAGAALFGSAFLIPSFAVSVLAFTPTDAGQLLLPSGALFIGALLIAAFLM
                     QARRVPPVATVPFGILMIMGAMWMLSGSTIQSGADDMMAAILLRGAGLGFLFLSITLI
                     AFSDLKSRNLAAGIGLFNTGRQLGGLVGVAALQTLIDHNVAHNLAVLGANVTAGAPSV
                     AERLATSAAMLTAKGMDAAAASRGAASLLGRAAAGQSTVIAFDTAFNAVALLFVIAAP
                     LLVGVKIGLSRLRKHV"
     sig_peptide     775782..775862
                     /locus_tag="Smed_4284"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.764) with cleavage site probability 0.435 at
                     residue 27"
     misc_feature    775833..777293
                     /locus_tag="Smed_4284"
                     /note="drug resistance transporter, EmrB/QacA subfamily;
                     Region: efflux_EmrB; TIGR00711"
                     /db_xref="CDD:129794"
     misc_feature    775839..>776312
                     /locus_tag="Smed_4284"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    order(775881..775883,775890..775898,775902..775907,
                     775956..775958,775965..775970,775977..775979,
                     775989..775994,775998..776003,776139..776144,
                     776151..776156,776163..776168,776175..776177,
                     776211..776216,776223..776228,776244..776246)
                     /locus_tag="Smed_4284"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            777581..779398
                     /locus_tag="Smed_4285"
                     /db_xref="GeneID:5319121"
     CDS             777581..779398
                     /locus_tag="Smed_4285"
                     /note="PFAM: peptidase M20;
                     KEGG: sme:SMb20697 putative peptidase, similar to arginine
                     utilization protein RocB"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M20"
                     /protein_id="YP_001313023.1"
                     /db_xref="GI:150376427"
                     /db_xref="InterPro:IPR002933"
                     /db_xref="GeneID:5319121"
                     /translation="MKNAQEKTASRAESRIDGEQVRQIALRITSWPSETGTPGEASFA
                     DRLHALLRELPYFREHPEDLHLIASHGEPLTRNVVALVRGTGKRTLVMAGHFDTVSTD
                     NYHELKALACDSLALKDALIESLSARDDRSEQEERALQDLASGDFLPGRGLLDMKSGL
                     AVAIACLEQFAADTGRQGNLMLVATPDEERESRGMRSFRNALPGLVGDFDIEIAGGIN
                     LDVTSDQGDGSEGRAVYAGTIGKLLPFALVIGCSSHASYPFEGVSAQAMAAGILERLE
                     GNASLADRDDNDISPPPICLEAKDLRDGYEVTTPERFWIAFNWLYHAMTADALFARFR
                     EEVLTGANEAIEKFAAQSAEYGRLVGRRAGVMPATPHLMSFGELRAAAARVFGDGFDA
                     FYAEKESVFSQSDNPLVATRQLTEWLVGIARLSGPAIVIGFAGLHYPPSHLRLSEGND
                     RSLHQAVEKARASLGNDPARSLVWKPHFYGISDMSFLGLAAGDSHIVSDNTPISRLVD
                     RPGENALRFPTVNLGPGGGSSIRSSSAYTRLTPSRSSRIWFSRSRGAFSPTAVTETDA
                     ALVRLATDTFKQGLRRRPNEAPRFYAFPLGNQRSGRPAL"
     misc_feature    777620..779146
                     /locus_tag="Smed_4285"
                     /note="Arginine degradation protein (predicted deacylase)
                     [Amino acid transport and metabolism]; Region: RocB;
                     COG4187"
                     /db_xref="CDD:226650"
     gene            779607..780854
                     /locus_tag="Smed_4286"
                     /db_xref="GeneID:5319122"
     CDS             779607..780854
                     /locus_tag="Smed_4286"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: rde:RD1_3953 sugar ABC transporter,
                     substrate-binding domain, putative"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313024.1"
                     /db_xref="GI:150376428"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5319122"
                     /translation="MKKTAFFASAATIMLSGLVAVQAARAECGIEKGTVRILSNDFEA
                     LRLVVSEAEKCASATVKVSKNQTSEHKNLQVPALKINPAQYTVAVIANNSIVPLLNEG
                     LLRPLDDLVAKYGQDLQPTQLIKLDGKVMAIAFMGNSQHLFFRKDILEKAGLQQPKSY
                     EDVLAAAKAIKEKGLMQYPLAASNKAGWDLAAEFVNMYLGYGGELFAAGSAAPAINNE
                     KGLATLKTMKAMTEYMNPDYMTYNADEIVKGYAAGKTAIINAWGSLAGGVIDPVKTPA
                     EIADNTVLGAAPTVGGGSIPAAALWWDGFSIAKNISDEDAEASFRAMVHGIRPEVGQK
                     HPALATWLTKGYQPGPNAVGVLATANGGAKPYPMLPYMGLLHSALGSELAEYMQGRES
                     AEEALKDVEASYSAAAKEGGFLK"
     misc_feature    779607..780836
                     /locus_tag="Smed_4286"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     sig_peptide     779607..779678
                     /locus_tag="Smed_4286"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.801 at
                     residue 24"
     misc_feature    <780072..780554
                     /locus_tag="Smed_4286"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     gene            780963..781991
                     /locus_tag="Smed_4287"
                     /db_xref="GeneID:5319123"
     CDS             780963..781991
                     /locus_tag="Smed_4287"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: jan:Jann_3700 binding-protein-dependent transport
                     systems inner membrane component"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313025.1"
                     /db_xref="GI:150376429"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319123"
                     /translation="MPHRAFFAFIMPSLLAMLLFIALPIVSVAVQSLYVEHERVVTEV
                     ETCAPFAGCTTETRVDAEATEKLRDAEPLGRFNGFGTYLDRNHLATAEMNAILTDNAG
                     FADVASRIYNLPFYRALAFTLTYTFVVTPLAMLLGFCIALGVNAIPPFYKGPVIFFSL
                     LPMIVTPLVGALIIYWMSSPQGILGATLQSLLNDSTLSLKSSAVLTWVTLLVYGVWHN
                     APFSFVVFYAGLQTVPHDTLESAMIDGANRWERIRFVVIPHLMPLATFVALVQLMDNF
                     RVFEPIVGFSAEANATSLSWSIFNDLRGQVDQLFGSAAATSMLTIVGVVILLSPVLVR
                     TWREFNRR"
     sig_peptide     780963..781052
                     /locus_tag="Smed_4287"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.997) with cleavage site probability 0.811 at
                     residue 30"
     misc_feature    781317..781934
                     /locus_tag="Smed_4287"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(781365..781370,781377..781382,781395..781397,
                     781425..781436,781440..781469,781476..781481,
                     781485..781487,781602..781607,781617..781619,
                     781623..781625,781632..781637,781641..781643,
                     781653..781658,781665..781667,781716..781718,
                     781758..781763,781770..781772,781791..781802,
                     781809..781814,781851..781856,781884..781889,
                     781896..781901,781905..781910,781917..781922,
                     781929..781934)
                     /locus_tag="Smed_4287"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(781443..781487,781791..781808)
                     /locus_tag="Smed_4287"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(781485..781487,781587..781589,781809..781811,
                     781845..781847,781854..781856,781884..781886)
                     /locus_tag="Smed_4287"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(781668..781706,781722..781727,781737..781739)
                     /locus_tag="Smed_4287"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            782002..782883
                     /locus_tag="Smed_4288"
                     /db_xref="GeneID:5319124"
     CDS             782002..782883
                     /locus_tag="Smed_4288"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: rde:RD1_3950 putative sugar ABC transporter,
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313026.1"
                     /db_xref="GI:150376430"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319124"
                     /translation="MIVNKRRRPLPLTVLSTTFVLLWVLMAAFPFIWTVWGSFKVEQD
                     FFSRDSWWFAIEGSRTIAQTGSAFTGDGYYGAWVLRDFFSSVVNTVIVTLSVVVVSLT
                     FGTLGGYALARSGYRYTFWLLMLALVFRAMPHITLVSGYLLPFFEMNIWGHLPTAIIV
                     LVAINQPFTLWMLHSFFLSIPKDLDESAMVDGCSRFQAFRLVVIPVMWPGVITTGLFS
                     FLLAYNDFAVTAMLLSQPNQTMVPKIASFLGTIQQEGNVMFAVAAVVSATAPLFVLVM
                     FFQRQIVSGLTAGAVKG"
     sig_peptide     782002..782085
                     /locus_tag="Smed_4288"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.909) with cleavage site probability 0.387 at
                     residue 28"
     misc_feature    782011..782877
                     /locus_tag="Smed_4288"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    782326..782832
                     /locus_tag="Smed_4288"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(782335..782337,782365..782376,782380..782409,
                     782416..782421,782425..782427,782488..782493,
                     782497..782499,782503..782505,782512..782517,
                     782521..782523,782533..782538,782545..782547,
                     782596..782598,782638..782643,782650..782652,
                     782671..782682,782689..782694,782749..782754,
                     782782..782787,782794..782799,782803..782808,
                     782815..782820,782827..782832)
                     /locus_tag="Smed_4288"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(782383..782427,782671..782688)
                     /locus_tag="Smed_4288"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(782425..782427,782473..782475,782689..782691,
                     782743..782745,782752..782754,782782..782784)
                     /locus_tag="Smed_4288"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(782548..782586,782602..782607,782617..782619)
                     /locus_tag="Smed_4288"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            782889..783953
                     /locus_tag="Smed_4289"
                     /db_xref="GeneID:5318452"
     CDS             782889..783953
                     /locus_tag="Smed_4289"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: rde:RD1_3954 sugar ABC transporter, ATP-binding
                     protein, putative"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313027.1"
                     /db_xref="GI:150376431"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318452"
                     /translation="MAEIRLKNVSKRWHNFVGVDNFDLDIADREFLVLLGPSGCGKTT
                     TMRMIAGLDDISEGEIWLGDRMVNNLEPKDRDISMVFQSYGLYPNMTVYENIRFPLRV
                     RKVPKELHHEKVMQAARMVELVDFLERRPAALSGGQRQRVALGRAIVRQPAAFLMDEP
                     LSNLDAKLRVSTRAQIKNLQHTLKVTTIYVTHDQIEAMTLADRVVVMNKGVIQQVGTP
                     TDIYDNPANTFVASFIGSPAMNLVSGDIENGTFRGPGITIGGLQINVKGPVTLGFRAE
                     DASLVFEGGELGAEIYSMELLGEATMASFRMGDQLVSIKSGKEYRAEIGDVVHAAIPA
                     SICHLFDARTGVRIARTPGN"
     misc_feature    782889..783932
                     /locus_tag="Smed_4289"
                     /note="glycerol-3-phosphate transporter ATP-binding
                     subunit; Provisional; Region: ugpC; PRK11650"
                     /db_xref="CDD:236947"
     misc_feature    782898..783536
                     /locus_tag="Smed_4289"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    782994..783017
                     /locus_tag="Smed_4289"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    order(783003..783008,783012..783020,783132..783134,
                     783360..783365,783462..783464)
                     /locus_tag="Smed_4289"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    783123..783134
                     /locus_tag="Smed_4289"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    783288..783317
                     /locus_tag="Smed_4289"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    783348..783365
                     /locus_tag="Smed_4289"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    783372..783383
                     /locus_tag="Smed_4289"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    783450..783470
                     /locus_tag="Smed_4289"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     gene            784009..785316
                     /locus_tag="Smed_4290"
                     /db_xref="GeneID:5318453"
     CDS             784009..785316
                     /locus_tag="Smed_4290"
                     /EC_number="1.1.1.23"
                     /note="catalyzes the oxidation of L-histidinol to
                     L-histidinaldehyde and then to L-histidine in histidine
                     biosynthesis; functions as a dimer"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="YP_001313028.1"
                     /db_xref="GI:150376432"
                     /db_xref="InterPro:IPR001692"
                     /db_xref="GeneID:5318453"
                     /translation="MTVTYLKRGKPEAQRSEEDAKVRGIVESTLKDIETRGDQAVREL
                     SEKFDRFSPPSFRLSPSEIEAAMSRVSTRDMTDIDFAQTQIRRFAEAQRASMTDIEIE
                     TIPGVILGHRNIPVQSVGCYVPGGKFPMVASAHMSVLTAAVAGVPRIVASAPPQKGAP
                     HPAIVAAMHKAGAHEIYVLGGMQAVGAMALGTETIKPVDMLVGPGNAFVAEAKRQLYG
                     RVGIDLFAGPTETMVIADETVDAEICATDLLGQAEHGYNSPAVLVTNSRRLADETLAE
                     IGRLLSILPTADTASASWRDYGEVIVCDTYEEMLDVANEIASEHVQVMTDRDDWFLEN
                     MHSYGALFLGPRTNVANGDKVIGTNHTLPTRKAGRYTGGLWVGKFMKTHSYQKVLTDE
                     AAAEIGAYCSRLCLLEGFIGHAEQANVRVRRYGGRNIGYGGAA"
     misc_feature    784072..785259
                     /locus_tag="Smed_4290"
                     /note="histidinol dehydrogenase; Region: hisD; TIGR00069"
                     /db_xref="CDD:232808"
     misc_feature    784072..785247
                     /locus_tag="Smed_4290"
                     /note="Histidinol dehydrogenase, HisD, E.C 1.1.1.23.
                     Histidinol dehydrogenase catalyzes the last two steps in
                     the L-histidine biosynthesis pathway, which is conserved
                     in bacteria, archaea, fungi, and plants. These last two
                     steps are (i) the NAD-dependent...; Region: Histidinol_dh;
                     cd06572"
                     /db_xref="CDD:119329"
     misc_feature    order(784150..784152,784372..784374,784378..784383,
                     784405..784407,784468..784470,784546..784551,
                     784555..784557,784618..784626,784630..784635,
                     784768..784770)
                     /locus_tag="Smed_4290"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:119329"
     misc_feature    order(784225..784230,784237..784242,784246..784248,
                     784255..784260,784267..784272,784279..784284,
                     784309..784311,784315..784317,784327..784341,
                     784348..784350,784354..784356,784390..784404,
                     784603..784605,784648..784650,784660..784662,
                     784732..784737,784744..784749,784753..784761,
                     784765..784770,784978..784980,784993..784995,
                     785002..785007,785011..785037,785041..785043,
                     785047..785052,785056..785070,785074..785076,
                     785080..785082,785110..785115,785119..785133,
                     785137..785142,785149..785169,785173..785175,
                     785218..785223,785227..785247)
                     /locus_tag="Smed_4290"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:119329"
     misc_feature    order(784396..784398,784402..784404,784693..784695,
                     784768..784770,784963..784968,785053..785055,
                     785065..785070,785086..785088,785230..785232,
                     785236..785238,785245..785247)
                     /locus_tag="Smed_4290"
                     /note="product binding site; other site"
                     /db_xref="CDD:119329"
     misc_feature    order(784402..784404,784693..784695,784759..784761,
                     784768..784770,784963..784968,785053..785055,
                     785065..785070,785086..785088,785230..785232,
                     785236..785238,785245..785247)
                     /locus_tag="Smed_4290"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:119329"
     misc_feature    order(784759..784761,784768..784770,785065..785067,
                     785245..785247)
                     /locus_tag="Smed_4290"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:119329"
     misc_feature    784963..784968
                     /locus_tag="Smed_4290"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:119329"
     gene            785300..785437
                     /locus_tag="Smed_4291"
                     /db_xref="GeneID:5318454"
     CDS             785300..785437
                     /locus_tag="Smed_4291"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313029.1"
                     /db_xref="GI:150376433"
                     /db_xref="GeneID:5318454"
                     /translation="MAARRRPPDFQEANLDGFLHIGCRVALRACVSAPVLAVKQGSRP
                     S"
     gene            785434..786198
                     /locus_tag="Smed_4292"
                     /db_xref="GeneID:5318455"
     CDS             785434..786198
                     /locus_tag="Smed_4292"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR; KR
                     domain protein;
                     KEGG: rde:RD1_3945 dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001313030.1"
                     /db_xref="GI:150376434"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5318455"
                     /translation="MKLPRTPSFRLDGRRALVAGASSGIGLGCAVALAEAGAHVVLAA
                     RSPEKLDEAVEAIRREGLSAEALVLDVADLEATEAAVAAERPFQVLVNSAGIARHGPA
                     ADTAPEDFDAVFGLNVRGAYFLTRAVAKGLIAAGQPGSLINISSQMAHVGGIDRAVYS
                     ATKHAVEGFTKSMAIEWGPAAIRVNTICPTFIRTPLTKQTFSKPERVQWITEKIKLGR
                     LGRVEDIMGAVTYLASDASAMVTGTALMVDGGWTAD"
     sig_peptide     785434..785538
                     /locus_tag="Smed_4292"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.992 at
                     residue 35"
     misc_feature    785458..786192
                     /locus_tag="Smed_4292"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    785461..786186
                     /locus_tag="Smed_4292"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Validated; Region: fabG; PRK05653"
                     /db_xref="CDD:235546"
     misc_feature    order(785491..785493,785497..785502,785506..785508,
                     785563..785571,785710..785718,785863..785871,
                     785908..785910,785920..785922,785998..786009)
                     /locus_tag="Smed_4292"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    order(785782..785784,785869..785871,785908..785910,
                     785920..785922)
                     /locus_tag="Smed_4292"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            786198..787226
                     /locus_tag="Smed_4293"
                     /db_xref="GeneID:5318456"
     CDS             786198..787226
                     /locus_tag="Smed_4293"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     SMART: regulatory protein LacI;
                     KEGG: rde:RD1_3944 transcriptional regulatory protein,
                     LacI family, putative"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313031.1"
                     /db_xref="GI:150376435"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318456"
                     /translation="MANDKVTSNDVARLAGVSQSAVSRYFTPGTSVSKKTAEKIRAAA
                     EELGYRPNVLARSLITGRSRIIGLVVAYLENYFYPEVVERLSKALQDQGYHVLVFISS
                     IASENVDQITQEILDYQVDGIVLASANMSSELAARCHASGVPIVLFNRLQDDERLSAV
                     TSDNRAGGRQLAELFVSLGHRRCGYIAGFEGASTQRDRERGFREGLEAAGLPLSAREV
                     GNFRYEDAQAAARRMFAGPEHPDAVFVCNDHMAFAVMDVLRFELGLRIPDDVSVAGFD
                     DVPPARWPAYNLTTIRQNVDDMVAETVATLMHSIKEGEGAARRITLDGALVLRGSTRA
                     KALTEETR"
     misc_feature    786213..787199
                     /locus_tag="Smed_4293"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    786225..786377
                     /locus_tag="Smed_4293"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(786246..786260,786264..786269,786276..786278,
                     786291..786296,786303..786305,786342..786344,
                     786351..786353,786360..786365,786369..786374)
                     /locus_tag="Smed_4293"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    786342..786371
                     /locus_tag="Smed_4293"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    786390..787190
                     /locus_tag="Smed_4293"
                     /note="Ligand-binding domain of uncharacterized
                     DNA-binding regulatory proteins that are members of the
                     LacI-GalR family of bacterial transcription repressors;
                     Region: PBP1_LacI_like_2; cd06278"
                     /db_xref="CDD:107273"
     misc_feature    order(786390..786392,786429..786437,786444..786449,
                     786453..786458,786477..786491,786495..786497,
                     786528..786530,786537..786539,786546..786554,
                     786867..786869,786951..786953,786963..786965,
                     786972..786977)
                     /locus_tag="Smed_4293"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:107273"
     misc_feature    order(786426..786431,786438..786440,786573..786575,
                     786642..786644,786681..786683,786789..786791,
                     786858..786860,787023..787025,787074..787076)
                     /locus_tag="Smed_4293"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107273"
     gene            787292..788263
                     /locus_tag="Smed_4294"
                     /db_xref="GeneID:5318457"
     CDS             787292..788263
                     /locus_tag="Smed_4294"
                     /note="PFAM: Cupin 2 conserved barrel domain protein;
                     KEGG: rde:RD1_3942 cupin domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cupin"
                     /protein_id="YP_001313032.1"
                     /db_xref="GI:150376436"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="GeneID:5318457"
                     /translation="MQISQTEMEKRIVRYGELKPCRTAFIDAHTPGSNQKENFTIIGG
                     GVSESADQHVHIKDTPGFNIGAAGQPPKCRNSLHSHRTAEVFFVLKGRWRFFWGRWGN
                     AGEVVLEEGDIFNIPTGIFRGFENIGTDYGMIMAILGGDDAGGGVIWAPQVIEDARDH
                     GLVLGENGKLYDTKKGQSLPDGIKPMPLLTEEELKAFPETPVQEVVRDYVARYWDLMA
                     LAQKAPAKVIGEKALLRDKPGFEVELLTRGSIPEAAYVNERHEVLMVMRGHWELAWDG
                     GASVLAPGDTCAVPPGLQHSLVPAMTGEASLYRVVATGEKAGRTWRG"
     misc_feature    787499..787702
                     /locus_tag="Smed_4294"
                     /note="Cupin domain; Region: Cupin_2; pfam07883"
                     /db_xref="CDD:219618"
     gene            788446..789141
                     /locus_tag="Smed_4295"
                     /db_xref="GeneID:5318458"
     CDS             788446..789141
                     /locus_tag="Smed_4295"
                     /note="KEGG: rde:RD1_3940 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313033.1"
                     /db_xref="GI:150376437"
                     /db_xref="GeneID:5318458"
                     /translation="MDDELLSLLLMVDTPTVCNAIEVAQGKRGFDGFTRGTVVSSAPT
                     ARPVVGYARTAKIAAAAPSTEGPAVIKARRMDYYRHVASGAPPSVAVVEDMDYPHCVG
                     AFWGEINATVHRGLGLCGVMTNGVMRDLGDVPEDFPMIAGSVGPSHAFVHVKAIGVPV
                     SVFGLTVAPGDLVHADRHGAVVVPPDIIPVLAAAIEKLRATERLILEPARQQGFDLAK
                     FEEAWARFEAART"
     misc_feature    <788752..789066
                     /locus_tag="Smed_4295"
                     /note="Demethylmenaquinone methyltransferase; Region:
                     Methyltransf_6; cl00480"
                     /db_xref="CDD:241893"
     gene            789336..790760
                     /locus_tag="Smed_4296"
                     /db_xref="GeneID:5318459"
     CDS             789336..790760
                     /locus_tag="Smed_4296"
                     /note="PFAM: Amidase;
                     KEGG: syg:sync_2679 enantiomer-selective amidase"
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="YP_001313034.1"
                     /db_xref="GI:150376438"
                     /db_xref="InterPro:IPR000120"
                     /db_xref="GeneID:5318459"
                     /translation="MIENPADLPILEAAERLRDGRLTSVALTVAHLDRIAERNGAYHA
                     FLHVAAESALAEAARADEALGCGEDRGPLHGIPVAVKDLFDTAGMPTTYGSDVYAGYL
                     PTEDAEVVRRLRAAGAVLIGKLETYEFAMVGPVFDRSFPPAANPWDVRRFTGGSSSGS
                     AAAVAGGLVRTSVASDTGGSVRSPAAYCGVVGFKPTYGRIPARGVFVLSPSLDHVGLI
                     SASVAEAAITFDAIADAETTDAEPAASRLGGALSGLRIGYARKWFADDPETLPALLDA
                     VDGAASQLSLLGARIEEVALPAAPDFESVGAVIIHAEAFEAHRRQLAASGDGYSRKVF
                     QNILSGLCLTPEDLVRARHAAARLRDRIDRTVFARFDAILTATTLTPAIPFADFAGEA
                     ARWTPMRTIAFNVTGHPALSVPCGFANGLPLAIQLAGRAGDEATLCQIGHAYEQASDF
                     AASKPPLPFPRAASDGRTQPAPSE"
     misc_feature    789351..790703
                     /locus_tag="Smed_4296"
                     /note="Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit
                     and related amidases [Translation, ribosomal structure and
                     biogenesis]; Region: GatA; COG0154"
                     /db_xref="CDD:223232"
     misc_feature    789411..790649
                     /locus_tag="Smed_4296"
                     /note="Amidase; Region: Amidase; cl11426"
                     /db_xref="CDD:245612"
     gene            790851..791630
                     /locus_tag="Smed_4297"
                     /db_xref="GeneID:5318460"
     CDS             790851..791630
                     /locus_tag="Smed_4297"
                     /note="PFAM: alpha/beta hydrolase fold;
                     KEGG: rpb:RPB_4141 alpha/beta hydrolase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold protein"
                     /protein_id="YP_001313035.1"
                     /db_xref="GI:150376439"
                     /db_xref="InterPro:IPR000073"
                     /db_xref="InterPro:IPR003089"
                     /db_xref="GeneID:5318460"
                     /translation="MAWRGCARTPPSELTMTASPNDEPRPPLLLLPGTACDQRVFASL
                     IDRLGDYPVLIGDMGGARTMAALAGNILAAAPPYFLLAGFSLGGICALEMVAQQPERI
                     GKLALIDTTARPDPAENAAVRRKAVADAREKGMDGFILDNWPRLVAPTNVHDGSLRDT
                     IVAMARDCGPDRLAEHAEVAISRADSRRRLAEIRQPTLVLAGAHEEVCPLDAQQELAA
                     GIPGAELHLIAEAGHFAPLENPDAVALVMKRWLEAGSGPFS"
     misc_feature    790932..791582
                     /locus_tag="Smed_4297"
                     /note="Alpha/beta hydrolase family; Region: Abhydrolase_6;
                     pfam12697"
                     /db_xref="CDD:221720"
     gene            791659..792837
                     /locus_tag="Smed_4298"
                     /db_xref="GeneID:5318461"
     CDS             791659..792837
                     /locus_tag="Smed_4298"
                     /note="PFAM: protein of unknown function DUF1486;
                     KEGG: jan:Jann_4086 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313036.1"
                     /db_xref="GI:150376440"
                     /db_xref="InterPro:IPR009959"
                     /db_xref="GeneID:5318461"
                     /translation="MSDDTTKAVKAVAQNQRKDPAEQVLQVERRDYTELAPVDRPRSQ
                     SLDGFDEIYTDIVDYIVRCTHRIWDERDIGLIYTHYTHNCVLYGTLGTIYNREDVVRD
                     TIQRLVSLPERRGMATQVLWSGNDVEGFYTSHLVTGSGRHTQYGHFGPPTGRTFVART
                     IADCMIHRNKIYREWVVADTMAIIKQLGLDPHAFAGKLARSSFDKGLLSLDIGENRRL
                     LGQYPPEAEADVSIAHNDIEAHTLRWLHEVFNGRMFGRIKDVYAPTCQYHGPLMKELY
                     GVAAVTHQHLGLIGSIPDAAYSAQHICSNPCEEGGVKVAVRWLMEGHHLGYGILQDLG
                     EPTGARLQVMGMTHYHYKDGKIVDEWNVYDELSLLVQVKLAEMARQSGSANAEAHGAS
                     "
     misc_feature    792373..792771
                     /locus_tag="Smed_4298"
                     /note="Nuclear transport factor 2 (NTF2-like) superfamily.
                     This family includes members of the NTF2 family,
                     Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases,
                     and the beta subunit of Ring hydroxylating dioxygenases.
                     This family is a classic example of...; Region: NTF2_like;
                     cl09109"
                     /db_xref="CDD:245009"
     gene            complement(793014..793787)
                     /locus_tag="Smed_4299"
                     /db_xref="GeneID:5319303"
     CDS             complement(793014..793787)
                     /locus_tag="Smed_4299"
                     /note="TIGRFAM: exodeoxyribonuclease III;
                     exodeoxyribonuclease III Xth;
                     PFAM: Endonuclease/exonuclease/phosphatase;
                     KEGG: sme:SMb20689 probable exodeoxyribonuclease III
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III Xth"
                     /protein_id="YP_001313037.1"
                     /db_xref="GI:150376441"
                     /db_xref="InterPro:IPR000097"
                     /db_xref="InterPro:IPR004808"
                     /db_xref="InterPro:IPR005135"
                     /db_xref="GeneID:5319303"
                     /translation="MKIATFNINGVNKRLDHLLIWLAAAGPDVVCLQELKATDGQFPE
                     AAIEAAGYGAVWLGQTAWNGVAILARGCEPVLTRTGLPGDPSDTQSRYIEAAVNGILI
                     ASLYAPNGNPQPGPKFDYKLAWHQRLNLHAAALLEARVPVLLAGDYNVVPEPRDIYPT
                     RSYDGNALVQPESRAAFKSLVEQGWLDALRKVHPQAQLFTFWDYRRNRWQRDAGLRLD
                     HILLSGKLKRRLTGAGIDREIRGLEGASDHAPVWITLRE"
     misc_feature    complement(793023..793787)
                     /locus_tag="Smed_4299"
                     /note="Escherichia coli exonuclease III (ExoIII) and
                     Neisseria meningitides NExo-like subfamily of the ExoIII
                     family purinic/apyrimidinic (AP) endonucleases; Region:
                     ExoIII-like_AP-endo; cd09086"
                     /db_xref="CDD:197320"
     misc_feature    complement(order(793044..793049,793134..793136,
                     793341..793343,793347..793349,793470..793472,
                     793686..793688,793767..793769))
                     /locus_tag="Smed_4299"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:197320"
     misc_feature    complement(order(793044..793046,793341..793343,
                     793347..793349,793461..793463,793470..793472,
                     793686..793688,793767..793769))
                     /locus_tag="Smed_4299"
                     /note="putative phosphate binding site [ion binding];
                     other site"
                     /db_xref="CDD:197320"
     misc_feature    complement(order(793044..793046,793053..793058,
                     793134..793139,793143..793145,793173..793178,
                     793185..793187,793341..793343,793347..793349,
                     793437..793439,793455..793457,793461..793463,
                     793470..793472,793605..793610,793686..793688,
                     793746..793754,793758..793763))
                     /locus_tag="Smed_4299"
                     /note="active site"
                     /db_xref="CDD:197320"
     misc_feature    complement(order(793044..793049,793686..793688,
                     793761..793763))
                     /locus_tag="Smed_4299"
                     /note="metal binding site A [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:197320"
     misc_feature    complement(order(793053..793058,793173..793178,
                     793437..793439,793455..793457,793461..793463,
                     793470..793472,793605..793610,793746..793754,
                     793758..793763))
                     /locus_tag="Smed_4299"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:197320"
     misc_feature    complement(order(793044..793046,793137..793139,
                     793143..793145,793185..793187,793341..793343,
                     793347..793349,793461..793463,793470..793472))
                     /locus_tag="Smed_4299"
                     /note="putative AP binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:197320"
     misc_feature    complement(order(793044..793046,793341..793343,
                     793347..793349,793470..793472))
                     /locus_tag="Smed_4299"
                     /note="putative metal binding site B [ion binding]; other
                     site"
                     /db_xref="CDD:197320"
     gene            complement(793795..794436)
                     /locus_tag="Smed_4300"
                     /db_xref="GeneID:5319304"
     CDS             complement(793795..794436)
                     /locus_tag="Smed_4300"
                     /note="KEGG: sme:SMb20688 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313038.1"
                     /db_xref="GI:150376442"
                     /db_xref="GeneID:5319304"
                     /translation="MGGNFLFDGPGDAPVTILLAHGAGAPMDSASMNATAQALAGAGF
                     RVARFEFGYMAARRTSEGRKPPPRAETLNPEYRAAIAELGFKGALVIGGKSMGGRVAS
                     MVADDLHAEGKIAGLLCLGYPFHPPGKPEQLRTRHLADLQTPTLICQGTRDEFGTRDE
                     VSQYALSDRIELLWLEDGDHDLKPRKTISGFSTADHLKTLAEAAARWAGRLVS"
     misc_feature    complement(793798..794436)
                     /locus_tag="Smed_4300"
                     /note="Predicted hydrolase of the alpha/beta-hydrolase
                     fold [General function prediction only]; Region: COG3571"
                     /db_xref="CDD:226101"
     gene            complement(794438..795523)
                     /locus_tag="Smed_4301"
                     /db_xref="GeneID:5319305"
     CDS             complement(794438..795523)
                     /locus_tag="Smed_4301"
                     /note="PFAM: TPR repeat-containing protein;
                     Tetratricopeptide TPR_2 repeat protein;
                     SMART: Tetratricopeptide domain protein;
                     KEGG: sme:SMb20687 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313039.1"
                     /db_xref="GI:150376443"
                     /db_xref="InterPro:IPR001440"
                     /db_xref="InterPro:IPR013026"
                     /db_xref="InterPro:IPR013105"
                     /db_xref="GeneID:5319305"
                     /translation="MAVAGRTFGIIGALAAFPRRLAAREVERQGGHLRRGVARQTNYV
                     VFGRGLLSRATEAEIEKRFDGESGAHGRVLSENGFLRLLGLARAAETSALARQSLIDQ
                     SGISPRHLDLLSLFDAFEHDGEPYSFRDLILARKYAGLTASGAGWSAIARSVHRSGNV
                     ASLTALSLQHEGNDTIYARRAEGLSELDGQMLLDVGSPDEEALEDLFALAEAAEEAGD
                     YDEAAAFYQRYLAIDRTDSVASFNRANCLRAAGQEAEAAHDYARAIKLDPSFVEAWFN
                     LAGLMEERGRRDTARRHLTKAIELDGGYADAVFNLAKLEFDAGNLTEARRWWMRYLEL
                     DQDSEWARKAERGVQFVNLQLLSRTAG"
     misc_feature    complement(794621..794818)
                     /locus_tag="Smed_4301"
                     /note="TPR repeat; Region: TPR_11; pfam13414"
                     /db_xref="CDD:222112"
     misc_feature    complement(794513..794809)
                     /locus_tag="Smed_4301"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cd00189"
                     /db_xref="CDD:238112"
     misc_feature    complement(order(794570..794575,794582..794587,
                     794594..794599,794675..794680,794687..794692,
                     794696..794701,794786..794791,794798..794803,
                     794807..794809))
                     /locus_tag="Smed_4301"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     misc_feature    complement(order(794531..794533,794540..794542,
                     794552..794554,794588..794590,794633..794635,
                     794642..794644,794654..794656,794690..794692,
                     794735..794737,794744..794746,794756..794758,
                     794792..794794))
                     /locus_tag="Smed_4301"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     misc_feature    complement(794519..794710)
                     /locus_tag="Smed_4301"
                     /note="TPR repeat; Region: TPR_11; pfam13414"
                     /db_xref="CDD:222112"
     gene            complement(795523..796422)
                     /locus_tag="Smed_4302"
                     /db_xref="GeneID:5319306"
     CDS             complement(795523..796422)
                     /locus_tag="Smed_4302"
                     /note="TIGRFAM: Ku family containing protein;
                     PFAM: Ku domain protein;
                     KEGG: sme:SMb20686 putative ATP-dependent DNA ligase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Ku family containing protein"
                     /protein_id="YP_001313040.1"
                     /db_xref="GI:150376444"
                     /db_xref="InterPro:IPR006164"
                     /db_xref="InterPro:IPR009187"
                     /db_xref="GeneID:5319306"
                     /translation="MAPRASWKGYLRLSLVSCPVRLYPATSASERISFNQLHKDTHNR
                     INMKPVDPELGLVERSDLVKGYEYEDKKYIIIEDSDLESVRIESNHTMNIEAFVDVDS
                     VDVIYQDAPYYLAPDGAMAEETFVVLREALRRSGKLAIARLVLSSRERVVTIGPRETG
                     MFVCTLRNPNEVRGTADYFGNIPVGEPDPEMLQLAEALIEQKATTFDPKKYEDRYEIA
                     LMQMIREKLKGHKPIIAQAPERGNVVNLMDALKASLSQSKPPARSKPKDVAAAKEPAV
                     KPAGAKRATAKSVVAKPAAKKKA"
     misc_feature    complement(795634..796422)
                     /locus_tag="Smed_4302"
                     /note="Ku-homolog [Replication, recombination, and
                     repair]; Region: COG1273"
                     /db_xref="CDD:224192"
     misc_feature    complement(795649..796413)
                     /locus_tag="Smed_4302"
                     /note="Ku-core domain, Ku-like subfamily; composed of
                     prokaryotic homologs of the eukaryotic DNA binding protein
                     Ku. The alignment includes the core domain shared by the
                     prokaryotic YkoV-like proteins and the eukaryotic Ku70 and
                     Ku80. The prokaryotic Ku...; Region: KU_like; cd00789"
                     /db_xref="CDD:238408"
     misc_feature    complement(order(795985..795987,796276..796278,
                     796321..796323,796351..796353,796408..796410))
                     /locus_tag="Smed_4302"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238408"
     misc_feature    complement(order(795661..795663,795670..795672,
                     795745..795747,795784..795792,795805..795807,
                     795817..795819,795904..795906,795910..795918,
                     795997..795999,796054..796056,796099..796101,
                     796129..796134,796138..796140,796195..796197,
                     796204..796209,796219..796224,796228..796230,
                     796234..796242,796252..796254,796267..796275,
                     796279..796290,796297..796299,796312..796323,
                     796336..796338,796342..796353,796372..796374))
                     /locus_tag="Smed_4302"
                     /note="putative homodimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238408"
     gene            complement(796510..798963)
                     /locus_tag="Smed_4303"
                     /db_xref="GeneID:5319307"
     CDS             complement(796510..798963)
                     /locus_tag="Smed_4303"
                     /note="TIGRFAM: DNA ligase D; DNA ligase D
                     3'-phosphoesterase domain; DNA polymerase LigD polymerase
                     domain; DNA polymerase LigD ligase region;
                     PFAM: DNA primase small subunit; ATP dependent DNA ligase
                     domain protein; ATP dependent DNA ligase;
                     KEGG: sme:SMb20685 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA ligase D"
                     /protein_id="YP_001313041.1"
                     /db_xref="GI:150376445"
                     /db_xref="InterPro:IPR002755"
                     /db_xref="InterPro:IPR012309"
                     /db_xref="InterPro:IPR012310"
                     /db_xref="InterPro:IPR014143"
                     /db_xref="InterPro:IPR014144"
                     /db_xref="InterPro:IPR014145"
                     /db_xref="InterPro:IPR014146"
                     /db_xref="GeneID:5319307"
                     /translation="MATSKLDAYRGKRDFSKTPEPAGNLSGGGNRFVVHKHHAAADHY
                     DLRLEVGDVLKSWAVPKGPSLNPADKRLAVATEDHPLDYIDFEGVIPEGEYGGGPMIV
                     WDKGVWAPMGDVEQDLRKGAFKFRLAGEKLKGGWMLTRLKPRPGEEDQRNWLLFKERD
                     LAADTSIDILAARPESVKSGRRIEELVEKPKAAPKPVKLNPRALPGAVEGAAPHRVEP
                     QLATPTVLPPEAEKGKKPEVWLHEIKFDGYRTMAHLADGRVRLITRGGLDWTKRYGDL
                     PEAFRRLPCRDAIIDGEIVVLDETGVSRFALLQDALSTGAGNSLVFYAFDLLHLNGWN
                     LFDAPLEKRKTLLKQLLAGQVTDRSAIQFSDHVVGEGRALYDQASEMGLEGIVSKRLS
                     APYRSGRSKTWTKTKALKAEDFVIVGYTVSQAAEGLAALALGEWSDGELAYRGKVGTG
                     FDAAMLEKLLERLEPLRSGAARLEGAPKEIIWVRPLLRAQIHYGNRTTDNVLRHAVFK
                     GLRDVELTTPVSPSRKRLISDADLASISITNPTRRLFGKSGPTKLDLAVYYAMIGDFM
                     LPHILGRPVSLVRCPSGRTQDCFFQRHPFTGMPPSVATFEAINSEGESRTYLSVEDAK
                     GYLALAQFGVVEFHNWGATRRLLGKPDRVVFDLDPGEGIAWREVVEAAIHIKSELEAL
                     DLVPFVKTSGGKGVHVVVPVKPKLDWKKFHPATSALAGRLAATAPDSFTTTMGKNNRV
                     KRIFIDYHRNARSHTWAAPYSLRARTNLPASTPLSWADLEAIDAPQDLNYSSLPGLLA
                     SSGDPWADIDAFARDLPLL"
     misc_feature    complement(796522..798963)
                     /locus_tag="Smed_4303"
                     /note="ATP-dependent DNA ligase; Reviewed; Region: ligD;
                     PRK05972"
                     /db_xref="CDD:235658"
     misc_feature    complement(798484..798948)
                     /locus_tag="Smed_4303"
                     /note="DNA ligase D, 3&apos;-phosphoesterase domain;
                     Region: LigD_PE_dom; TIGR02777"
                     /db_xref="CDD:131824"
     misc_feature    complement(797743..798318)
                     /locus_tag="Smed_4303"
                     /note="Adenylation domain of Mycobacterium tuberculosis
                     LigD and LigC-like ATP-dependent DNA ligases; Region:
                     Adenylation_DNA_ligase_LigD_LigC; cd07906"
                     /db_xref="CDD:185715"
     misc_feature    complement(order(797749..797751,797755..797757,
                     797797..797799,797803..797805,797812..797814,
                     797989..797991,798049..798051,798085..798087,
                     798172..798174,798217..798225,798229..798240))
                     /locus_tag="Smed_4303"
                     /note="active site"
                     /db_xref="CDD:185715"
     misc_feature    complement(order(797743..797745,797749..797751,
                     797812..797814,798031..798039,798046..798051,
                     798157..798159,798163..798165,798169..798177,
                     798217..798225,798232..798234))
                     /locus_tag="Smed_4303"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:185715"
     misc_feature    complement(797428..797730)
                     /locus_tag="Smed_4303"
                     /note="The Oligonucleotide/oligosaccharide binding
                     (OB)-fold domain of ATP-dependent DNA ligase LigD is a
                     DNA-binding module that is part of the catalytic core
                     unit; Region: OBF_DNA_ligase_LigD; cd07971"
                     /db_xref="CDD:153440"
     misc_feature    complement(order(797446..797448,797452..797457,
                     797461..797463,797605..797622,797626..797631,
                     797674..797676))
                     /locus_tag="Smed_4303"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:153440"
     misc_feature    complement(796627..797310)
                     /locus_tag="Smed_4303"
                     /note="PaeLigD_Pol_like: Polymerase (Pol) domain of
                     bacterial LigD proteins similar to Pseudomonas aeruginosa
                     (Pae) LigD. The LigD Pol domain belongs to the
                     archaeal/eukaryal primase (AEP) superfamily. In
                     prokaryotes, LigD along with Ku is required for...;
                     Region: PaeLigD_Pol_like; cd04862"
                     /db_xref="CDD:240132"
     misc_feature    complement(order(796669..796677,796699..796701,
                     796717..796719,796726..796728,796873..796875,
                     796879..796884,796891..796893,796990..796992,
                     796996..796998,797050..797052,797194..797196))
                     /locus_tag="Smed_4303"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240132"
     gene            complement(799037..799873)
                     /locus_tag="Smed_4304"
                     /db_xref="GeneID:5319308"
     CDS             complement(799037..799873)
                     /locus_tag="Smed_4304"
                     /note="PFAM: protein of unknown function DUF861 cupin_3;
                     Cupin 2 conserved barrel domain protein;
                     KEGG: sme:SMb20684 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313042.1"
                     /db_xref="GI:150376446"
                     /db_xref="InterPro:IPR008579"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="GeneID:5319308"
                     /translation="MHKNYYFPEGGHPPQTNLLSDRAIFTEAYAIIPKGVMRDIVTSY
                     LPFWTNTRLWVLSRPLSGFAETFSQYIMEVGPSGGSKRPETDPRAEAVLFVVDGEFHL
                     TIDGETHLMQSGGYAFIPPGSEWSLRNESGSPTRFHWIRKAYERVEGIPLPEAIVTNE
                     RDIPPSPMPETDGRWATTRFVDPSDMRHDMHVTIVTFEPGGVIPFMETHVMEHGLYVL
                     EGKAVYRLNNDWVEVEAGDYMWLRAFCPQACYAGGPGKFRYLLYKDVNRHMTLGNPGR
                     LA"
     misc_feature    complement(799058..799870)
                     /locus_tag="Smed_4304"
                     /note="hypothetical protein; Provisional; Region:
                     PRK11171"
                     /db_xref="CDD:183011"
     misc_feature    complement(799454..799666)
                     /locus_tag="Smed_4304"
                     /note="Cupin domain; Region: Cupin_2; pfam07883"
                     /db_xref="CDD:219618"
     misc_feature    complement(799094..799294)
                     /locus_tag="Smed_4304"
                     /note="Cupin domain; Region: Cupin_2; pfam07883"
                     /db_xref="CDD:219618"
     gene            800008..800892
                     /locus_tag="Smed_4305"
                     /db_xref="GeneID:5319309"
     CDS             800008..800892
                     /locus_tag="Smed_4305"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb20683 putative transcriptional regulator,
                     LysR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001313043.1"
                     /db_xref="GI:150376447"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5319309"
                     /translation="MELRHLRYFVAVADAASFTAAARGLNISQPPLSQQIRDLEAEVG
                     TRLFERSSRNVELTEAGANFLEHARMILGQVEHATHQARAIGSGQVGTLNIATTGSVL
                     LGPLSNLIARFRDAWPGVFVRIHEMDPEAQEAALLSHRTDLSFVRKPRNHPHLVALVA
                     WQEKVDVALPEHHRLANSGTIELGDLRQESFVFLRLADSRFARYLHDCCVTAGFVPDI
                     TNEVVESYSLTSLVAAGLGVALVPNCISTLSRPGVVYRPLADPAPEADVHVISRPNPG
                     PVVSAFLETAQSTAVNPR"
     misc_feature    800014..800859
                     /locus_tag="Smed_4305"
                     /note="DNA-binding transcriptional activator XapR;
                     Provisional; Region: PRK09986"
                     /db_xref="CDD:182183"
     misc_feature    800014..800190
                     /locus_tag="Smed_4305"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    800281..800865
                     /locus_tag="Smed_4305"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator XapR involved in
                     xanthosine catabolism, contains the type 2 periplasmic
                     binding fold; Region: PBP2_XapR; cd08449"
                     /db_xref="CDD:176140"
     misc_feature    order(800296..800298,800317..800319,800326..800331,
                     800335..800340,800347..800349,800371..800373,
                     800377..800379,800383..800385,800515..800517,
                     800614..800619,800674..800679,800695..800700,
                     800704..800709,800761..800763)
                     /locus_tag="Smed_4305"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176140"
     misc_feature    order(800299..800301,800446..800448,800587..800592,
                     800608..800610)
                     /locus_tag="Smed_4305"
                     /note="putative substrate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:176140"
     gene            801139..803187
                     /locus_tag="Smed_4306"
                     /db_xref="GeneID:5319310"
     CDS             801139..803187
                     /locus_tag="Smed_4306"
                     /note="PFAM: Hemolysin-type calcium-binding region;
                     KEGG: sme:SMc04171 putative hemolysin-type calcium-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Hemolysin-type calcium-binding protein"
                     /protein_id="YP_001313044.1"
                     /db_xref="GI:150376448"
                     /db_xref="InterPro:IPR001343"
                     /db_xref="InterPro:IPR003995"
                     /db_xref="GeneID:5319310"
                     /translation="MAAILGSTGYDILQGTDEADHIWGLHGGDTIDAGGGDDFVDGGD
                     LSDVLTSSSGYDRLHGGAGDDQIVLTGTGGAVTGGLGFDRLTVDISMLSDQLVFNGVS
                     GHGIIGYGSAEERHIFFHDVEWLSIVSGSGNDRIVGTAGHDRISTGVGIDVVVAGAGN
                     DVITNTGGQDRLEGGDGNDRFVLVGTGSTVFGGAGDDTLTLDLAATLGDIVFNANTGH
                     AIIASRTPDERHVFAQHSEIERIEVITGSGNDRVQGTTSGDVIKTDAGDDVVDGGAGD
                     DSITDGSGANHLSGGDGSDLITTTLYSASVDGGAGRDSVRIEERSRMSDVAIDFVSGT
                     ASTRTVFRNIETASLALGAGNDAVITTDFLAIFVDAGAGDDRLVGGARSDAFHGEDVN
                     DRIDSGAGNDTITTGLGDDLASGGDGNDSLANDGGKDILDGGAGDDWIADAIPGSGSL
                     GDGSVMLGGDGNDAFRASFTGEVDGGDGRDLLQLRLGSLSAAIDFDAAQGAIQTGLTF
                     ANIEDFTVTTGVANDVLRGGDGNDEFDSLSGNDLLEGHGGNDILRGYSDWDRLFGGDG
                     DDRLEGGPHDDLLSGGNGTDTLIGGTGADTFLWSDEVAGQSGIDHIVDLDFGDVIAFS
                     AAACERTGIHDHAGFVAAATNTADGVYVAFNGSAADGILIENALIATLTADDLVFGFA
                     "
     gene            complement(803330..804151)
                     /locus_tag="Smed_4307"
                     /db_xref="GeneID:5319311"
     CDS             complement(803330..804151)
                     /locus_tag="Smed_4307"
                     /note="PFAM: regulatory protein IclR; Transcriptional
                     regulator IclR;
                     KEGG: sme:SMb20682 putative acetate operon repressor IclR
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator IclR"
                     /protein_id="YP_001313045.1"
                     /db_xref="GI:150376449"
                     /db_xref="InterPro:IPR005471"
                     /db_xref="InterPro:IPR014757"
                     /db_xref="GeneID:5319311"
                     /translation="MDASGKGKRGRKAGENATPASVQVLDRSLSLLAIIAEGDGSTLT
                     TLSERSGMAPSTVHRLLTSLAQHGMVTNDTETGTWTVGVKAFEIGNAFLRFRKLGTIS
                     RPFLKRLMDESGETANIGIEDDGDVVFISQVESHAPMRAFFRPGRRGPIHASGIGKAI
                     LSTWSDTEIAKTLNGRPLPCFTGRTLATLPDLIRNVQEIRFRGWSIDDEEHTLGMRCI
                     AAPLFNEYGEAIGGISISGPSVRVDDERLRVLGPAVRRTADELTRAIGGHRPEEG"
     misc_feature    complement(803819..804088)
                     /locus_tag="Smed_4307"
                     /note="helix_turn_helix isocitrate lyase regulation;
                     Region: HTH_ICLR; smart00346"
                     /db_xref="CDD:214629"
     misc_feature    complement(803351..804085)
                     /locus_tag="Smed_4307"
                     /note="Transcriptional regulator [Transcription]; Region:
                     IclR; COG1414"
                     /db_xref="CDD:224332"
     misc_feature    complement(803360..803743)
                     /locus_tag="Smed_4307"
                     /note="Bacterial transcriptional regulator; Region: IclR;
                     pfam01614"
                     /db_xref="CDD:201890"
     gene            804315..806099
                     /locus_tag="Smed_4308"
                     /db_xref="GeneID:5319312"
     CDS             804315..806099
                     /locus_tag="Smed_4308"
                     /EC_number="4.1.1.47"
                     /note="catalyzes the formation of
                     2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from
                     two molecules of glyoxylate"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="YP_001313046.1"
                     /db_xref="GI:150376450"
                     /db_xref="InterPro:IPR006397"
                     /db_xref="InterPro:IPR011766"
                     /db_xref="InterPro:IPR012000"
                     /db_xref="InterPro:IPR012001"
                     /db_xref="GeneID:5319312"
                     /translation="MAKMRAVDAAVFVLEKEGIDCAFGVPGAAINPFYSALRARGSIR
                     HILARHVEGASHMAEGYTRAKHGNIGVCIGTSGPAGTDMITGLYSASADSIPILCITG
                     QAPRARLDKEDFQAVDIAKIAAPVTKWAVTVMEPALVPFVFQKAFHLMRSGRPGPVLI
                     DLPVDVQLAEIEFDPETYEPLTPYKPAATRAQAEKALAMLNAAERPLIVAGGGIINAD
                     ASDLLTEFAEITGVPVVPTLMGWGVIPDDHPLMAGMCGLQTSHRYGNATLLASDFVFG
                     IGNRWANRHTGNVPTYTEGRKFIHVDIEPTQIGRVFAPDFGIVSDAGAALKLFLDVAT
                     EWKTAGKLRDWSGWAGECRERKRTMLRKTHFDQTPLKPQRVYEEMNKAFGRDTCYVST
                     IGLSQIAGAQFLHVYKPRNWINCGQAGPLGWTLPAALGVRAADPNRPIVALSGDYDFQ
                     FLIEELAVGAQHKLPYLHVVVNNSYLGLIRQAQRGFNMDFEVSLAFENINAEGDAEKG
                     YGVDHVAVAEGLGCKAIRVRSPNEFADAFDRAQALMEEHQVPVVIEFILERVTNIAMG
                     TDINSVVEFEELAERGEDAPTAVAALLD"
     misc_feature    804315..806090
                     /locus_tag="Smed_4308"
                     /note="glyoxylate carboligase; Provisional; Region:
                     PRK11269"
                     /db_xref="CDD:183066"
     misc_feature    804336..804806
                     /locus_tag="Smed_4308"
                     /note="Pyrimidine (PYR) binding domain of POX and related
                     proteins; Region: TPP_PYR_POX_like; cd07035"
                     /db_xref="CDD:132918"
     misc_feature    order(804375..804377,804390..804395,804405..804407,
                     804417..804419,804444..804464,804471..804473,
                     804480..804485,804492..804497,804501..804509,
                     804546..804548,804567..804569,804579..804581,
                     804588..804593)
                     /locus_tag="Smed_4308"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    order(804390..804398,804405..804407,804417..804419,
                     804447..804449,804453..804464,804468..804470,
                     804546..804548,804555..804560,804564..804569,
                     804576..804578,804678..804680,804687..804689)
                     /locus_tag="Smed_4308"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    order(804390..804392,804465..804467,804546..804548,
                     804558..804560)
                     /locus_tag="Smed_4308"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    804894..805295
                     /locus_tag="Smed_4308"
                     /note="Thiamine pyrophosphate enzyme, central domain;
                     Region: TPP_enzyme_M; pfam00205"
                     /db_xref="CDD:215786"
     misc_feature    805401..806012
                     /locus_tag="Smed_4308"
                     /note="Thiamine pyrophosphate (TPP) family, Gcl subfamily,
                     TPP-binding module; composed of proteins similar to
                     Escherichia coli glyoxylate carboligase (Gcl). E. coli
                     glyoxylate carboligase, plays a key role in glyoxylate
                     metabolism where it catalyzes the...; Region: TPP_Gcl;
                     cd02006"
                     /db_xref="CDD:238964"
     misc_feature    order(805575..805577,805647..805658,805731..805733,
                     805737..805739)
                     /locus_tag="Smed_4308"
                     /note="TPP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238964"
     gene            806129..806944
                     /locus_tag="Smed_4309"
                     /db_xref="GeneID:5318884"
     CDS             806129..806944
                     /locus_tag="Smed_4309"
                     /EC_number="5.3.1.22"
                     /note="PFAM: Xylose isomerase domain protein TIM barrel;
                     KEGG: sme:SMb20680 putative hydroxypyruvate isomerase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="YP_001313047.1"
                     /db_xref="GI:150376451"
                     /db_xref="InterPro:IPR012307"
                     /db_xref="GeneID:5318884"
                     /translation="MQRFAANLTMLFNEAPFLDRFALAAKAGFEGVEYLFPYDFDKTA
                     LRGELDRYGLTQVLHNLPAGNWAGGERGIAILPDRIDEFRKGVASAIDYATALGCPQV
                     NCLVGIAPDGVPDSVLRTTLVANLKLAAVELGKCGIRLLIEPINRFDIPGFYLNTLGQ
                     AASIIEEVGSDNLFIQYDLYHQQRTEGELVGTYKRHREKITHIQLADNPGRNEPGTGE
                     INYPFVFAALEAADYDGWIGCEYKPLTTTAEGLGWLGLERKRKQSADIIQIRS"
     misc_feature    806129..806902
                     /locus_tag="Smed_4309"
                     /note="Hydroxypyruvate isomerase [Carbohydrate transport
                     and metabolism]; Region: Hfi; COG3622"
                     /db_xref="CDD:226149"
     gene            806950..807834
                     /locus_tag="Smed_4310"
                     /db_xref="GeneID:5318885"
     CDS             806950..807834
                     /locus_tag="Smed_4310"
                     /EC_number="1.1.1.60"
                     /note="TIGRFAM: 2-hydroxy-3-oxopropionate reductase;
                     PFAM: 6-phosphogluconate dehydrogenase NAD-binding;
                     KEGG: sme:SMb20679 putative tartronate semialdehyde
                     reductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="YP_001313048.1"
                     /db_xref="GI:150376452"
                     /db_xref="InterPro:IPR002204"
                     /db_xref="InterPro:IPR006115"
                     /db_xref="InterPro:IPR006183"
                     /db_xref="InterPro:IPR006398"
                     /db_xref="GeneID:5318885"
                     /translation="MASIGFIGLGIMGTPMARHLQDAGHKIITSKFAIPPRQELVDNG
                     LEIVETPKALAETVDTIILMLPDTPEVKDVLFGENGVHFGLSEGKLVIDMSSISPIET
                     KEFARKVRETGAEYIDAPVSGGEVGAKNASLSIMAGGKQSSFERALPLFKLMGKNITL
                     VGDCGDGQVTKVANQIIVALTIEAVSEALVFASKAGADPARVREALMGGFASSRILEV
                     HGDRMIKRTFEPGFRISLHQKDLNLALQGAKSLGISLPNTAATQELFNNCAANGDSGL
                     DHSGLVRALERMANHEVA"
     misc_feature    806959..807831
                     /locus_tag="Smed_4310"
                     /note="tartronate semialdehyde reductase; Provisional;
                     Region: PRK15059"
                     /db_xref="CDD:185019"
     misc_feature    806959..>807405
                     /locus_tag="Smed_4310"
                     /note="6-phosphogluconate dehydrogenase-like protein;
                     Reviewed; Region: PRK09599"
                     /db_xref="CDD:236582"
     gene            807941..809209
                     /locus_tag="Smed_4311"
                     /db_xref="GeneID:5318886"
     CDS             807941..809209
                     /locus_tag="Smed_4311"
                     /EC_number="1.1.1.81"
                     /note="PFAM: MOFRL domain protein;
                     KEGG: sme:SMb20678 putative hydroxypyruvate reductase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate reductase"
                     /protein_id="YP_001313049.1"
                     /db_xref="GI:150376453"
                     /db_xref="InterPro:IPR000897"
                     /db_xref="InterPro:IPR007835"
                     /db_xref="GeneID:5318886"
                     /translation="MAAVANPRQFLETLFASAVSAADPERTIAANLPERPKGRTVVIG
                     AGKGAAQMARAFESAWDGPLSGVVVTRYGFGAHCNNIEILEASHPLPDEGGLKASKRL
                     LAQVGSLTVDDLVVALICGGGSALLPAPPPGLSLEDEIAVNRALLASGAPISAMNAVR
                     KHVSLIKGGRLAAAAHPARVVSLVVSDIPGDDAALVASGPTIADEASREEALKIIERY
                     RLALPEKVMHWLASEAADAPGPSDPRFARNEVRLIASASVSLEAAAAKARAAGVEAVI
                     LSDAIEGEARDVGLVHAAIARETAMRDRPFSRPVVLLSGGETTVTVRGEGRGGRNSEF
                     LLSLALGIDGIGGISALAADTDGIDGSEDNAGAFADHTTIARLLAQRLDAAALLQGND
                     SWAAFDALGDLFKPGPTGTNVNDFRAVLIQ"
     misc_feature    807944..809206
                     /locus_tag="Smed_4311"
                     /note="Putative glycerate kinase [Carbohydrate transport
                     and metabolism]; Region: GckA; COG2379"
                     /db_xref="CDD:225254"
     misc_feature    807965..808630
                     /locus_tag="Smed_4311"
                     /note="Domain of unknown function (DUF4147); Region:
                     DUF4147; pfam13660"
                     /db_xref="CDD:222296"
     misc_feature    808865..809185
                     /locus_tag="Smed_4311"
                     /note="MOFRL family; Region: MOFRL; pfam05161"
                     /db_xref="CDD:203185"
     gene            809257..809748
                     /locus_tag="Smed_4312"
                     /db_xref="GeneID:5318887"
     CDS             809257..809748
                     /locus_tag="Smed_4312"
                     /EC_number="3.5.3.19"
                     /note="catalyzes the formation of glyoxylate from
                     (S)-ureidoglycolate"
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate hydrolase"
                     /protein_id="YP_001313050.1"
                     /db_xref="GI:150376454"
                     /db_xref="InterPro:IPR007247"
                     /db_xref="GeneID:5318887"
                     /translation="MIPLPIRPLAHSAFAPFGDIIEPDDAKSFPINAGKCIRYHDLAK
                     VETSGPEARTLVSLLRGEPYEIPLALKMVERHPLGSQAFIPLTENPFLVVVAPDEGGQ
                     PGEPIAFETAPGQGVNIAQNVWHGILTPLRSTSEFVVIDRGGSGCNLEEHFFDKPYQV
                     EYA"
     misc_feature    809257..809745
                     /locus_tag="Smed_4312"
                     /note="Ureidoglycolate hydrolase [Nucleotide transport and
                     metabolism]; Region: DAL3; COG3194"
                     /db_xref="CDD:225735"
     misc_feature    809257..809745
                     /locus_tag="Smed_4312"
                     /note="ureidoglycolate hydrolase; Provisional; Region:
                     PRK13395"
                     /db_xref="CDD:237375"
     gene            809826..810779
                     /locus_tag="Smed_4313"
                     /db_xref="GeneID:5318888"
     CDS             809826..810779
                     /locus_tag="Smed_4313"
                     /note="PFAM: protein of unknown function DUF930;
                     KEGG: sme:SMb20676 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313051.1"
                     /db_xref="GI:150376455"
                     /db_xref="InterPro:IPR009273"
                     /db_xref="GeneID:5318888"
                     /translation="MQQFARKMWGETGWGMPTSLALHLALALLLLVRLPELSAPAKEQ
                     SVSVELVPTPKNEKKPEQKPTKQKSDEARNQRARAQPQSFESAAAPTEKEKPPEPDLP
                     PAAPKKTETPSVRPEASRPAPAKPENAANERPAEKRTALAELRVDSTGAANKAADAAA
                     APPAAPIPQEKPVFEEARAEPTQNPAEASAERESSQLVQAKELYSKNALSDPHVKQAI
                     GRLPPKKRIVQLCTIEALEQIRHQRPGAIPDMFGRPDGGFASETALKADGAVFRSQGK
                     WYSFDFTCEVNPEATSVTSFSFAIGKAIPKSEWGARQLPSN"
     misc_feature    810477..810770
                     /locus_tag="Smed_4313"
                     /note="Domain of Unknown Function (DUF930); Region:
                     DUF930; pfam06059"
                     /db_xref="CDD:114763"
     gene            810996..811571
                     /locus_tag="Smed_4314"
                     /db_xref="GeneID:5318889"
     CDS             810996..811571
                     /locus_tag="Smed_4314"
                     /note="PFAM: protein of unknown function DUF1349;
                     KEGG: sme:SMb20675 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313052.1"
                     /db_xref="GI:150376456"
                     /db_xref="InterPro:IPR009784"
                     /db_xref="GeneID:5318889"
                     /translation="MASGYRWLNEPASWKGGDRDLSLKTDGNTDFWRETFYGFVRDSG
                     HAYLRPVSGDFTASATIIGRYEQLYDQAGLMLRLNEREWIKCGIEYTDGLMHFSVVVT
                     RGVSDWSVIPLLDKVPSDPLEVRLTRHGDAVRVQFRFGEERWQMARLCPFSASDAEVG
                     VTACSPERAGFEARFREVRVGPPIARALHDG"
     misc_feature    810996..811562
                     /locus_tag="Smed_4314"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3506"
                     /db_xref="CDD:226037"
     gene            complement(811607..812665)
                     /locus_tag="Smed_4315"
                     /db_xref="GeneID:5318890"
     CDS             complement(811607..812665)
                     /locus_tag="Smed_4315"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: sme:SMb20674 putative transcriptional regulator,
                     LacI family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313053.1"
                     /db_xref="GI:150376457"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318890"
                     /translation="MRERRSSRKSSAPTMLDVAKVAGVSVATVSAVINSSAPVSPELR
                     SRIEQAIGQIGYKRNAIARSLKLGTTRTVGLMVADITNPFFTDVVAVIQEVLHRAGYA
                     VMLCCSDEDVILQDEQIALLIDRSVDGLIIAPAGDDETLKRMIAAASLPTVLIDRLCD
                     GIDTDAVVLDNRRAVQDATRYMLGLGHRRIGYISGALDTSTGRERLSGYRAALEAAGL
                     PFEESLIRIGNFREKDAYTAAIQLLTSPERPTGIFSANNLMVIGVMKAIRDIGLRCPD
                     DVSVASFDDFPWADVFQPHLTTIAQPVQAIGEQAAQLVLDRLSGASTETPRRLVLQGR
                     LVIRDSCRPVSLAQRAIA"
     misc_feature    complement(811634..812629)
                     /locus_tag="Smed_4315"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    complement(812468..>812569)
                     /locus_tag="Smed_4315"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    complement(order(812468..812473,812477..812482,
                     812489..812491,812498..812500,812537..812539,
                     812546..812551,812564..812566))
                     /locus_tag="Smed_4315"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    complement(812471..812500)
                     /locus_tag="Smed_4315"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    complement(811658..812452)
                     /locus_tag="Smed_4315"
                     /note="Ligand binding domain of the LacI tanscriptional
                     regulator family belonging to the type I
                     periplasmic-binding fold protein superfamily; Region:
                     PBP1_LacI_sugar_binding_like; cd06267"
                     /db_xref="CDD:107262"
     misc_feature    complement(order(811859..811864,811871..811873,
                     811883..811885,811967..811969,812288..812296,
                     812303..812305,812312..812314,812345..812347,
                     812351..812365,812384..812389,812393..812398,
                     812405..812413,812450..812452))
                     /locus_tag="Smed_4315"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107262"
     misc_feature    complement(order(811763..811765,811814..811816,
                     811976..811978,812051..812053,812159..812161,
                     812198..812200,812267..812269,812402..812404,
                     812411..812416))
                     /locus_tag="Smed_4315"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107262"
     gene            812837..814423
                     /locus_tag="Smed_4316"
                     /db_xref="GeneID:5318891"
     CDS             812837..814423
                     /locus_tag="Smed_4316"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20673 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313054.1"
                     /db_xref="GI:150376458"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318891"
                     /translation="MRDAVPTLLGDSVTTEPARPILAAEAVSKSFGGVAALKDVRFDL
                     RSGEIHALMGENGAGKSTLMKVLSGVYADYEGTVRVDGEIARFSSVRDAEAAGIAIIH
                     QELNLVPELGVADNIFLGRERVVAGLFVDRKASLEAARGLLNRLGIELDPEARVGQLR
                     VGEQQLVEIAKALSVEARILIMDEPTSALSSGECRRLFKIVRQLAADGVGIVYISHRI
                     DEVMQLSDRVTVFRDGRHVWTRPMAGLDEDTIIAAMVGRNLLDAHPVNRPKGAEPVLS
                     VSGLSLAVAGRHGWRDVLKGVSFDVHAGEILGIGGLLGAGRTEILETVFASNDGVRGG
                     EIRLDGIAVDIRSPRDARRLGFALVTEDRKAKGLHLQESIRDNVALPLVGRLARFGLR
                     SFERERALASRAVEALGVRCAGTDQTAGTLSGGNQQKVVIGKWLATGPRVLLLDEPTR
                     GIDVGAKREIYDLVFKLAADGLAIVVVSSELPELLLLADRILVMAEGRQTGLISREEA
                     SEERIMQLAAPRSTFGRSVA"
     misc_feature    812876..814393
                     /locus_tag="Smed_4316"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    812900..813553
                     /locus_tag="Smed_4316"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    812996..813019
                     /locus_tag="Smed_4316"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(813005..813010,813014..813022,813143..813145,
                     813383..813388,813482..813484)
                     /locus_tag="Smed_4316"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    813134..813145
                     /locus_tag="Smed_4316"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(813167..813178,813323..813340)
                     /locus_tag="Smed_4316"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    813371..813388
                     /locus_tag="Smed_4316"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    813395..813406
                     /locus_tag="Smed_4316"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    813470..813490
                     /locus_tag="Smed_4316"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    813647..814330
                     /locus_tag="Smed_4316"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            814420..815742
                     /locus_tag="Smed_4317"
                     /db_xref="GeneID:5318892"
     CDS             814420..815742
                     /locus_tag="Smed_4317"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20672 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001313055.1"
                     /db_xref="GI:150376459"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318892"
                     /translation="MTFLKALSRTKLYWGLIAIFLIGVLFSPVTSSGRNIFLSSGNLL
                     DVLRQVSTTGLIATGMTAVILTGGIDLSVGSLMAICTVVCAMLLTVPGDTAAIYLGLP
                     AVGLAVLILGAAVARFIFLNIEKSRSGEAHIRDIKLGGARGTVLPAIAGVVLCALVLS
                     FLLPQMQTKFGVFGVLLVAPAVGLLFGAVNGVIIVAGRLQPFIVTLAMMVTALGIARL
                     TAGQNNAVLPVYTGSNATADFDVLRQLLFGIVPMPGIFFIVAILLYGAVLRFTPFGRY
                     VYAIGGNEEAARLSGINAGRVKIVTYAVSGLLAGIAAVLYVAQYRQGKPDAGAGLELD
                     AIAAVVIGGTSLMGGRGSLAGTFCGVLIFGLLSNILQLHNINSNLQLVLKGVIIIGTV
                     LVQERNAYDLFAQLRLPGASRRPVQGDTSVEERTSRETLSLTMGGKKE"
     sig_peptide     814420..814515
                     /locus_tag="Smed_4317"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.967) with cleavage site probability 0.471 at
                     residue 32"
     misc_feature    814456..>814710
                     /locus_tag="Smed_4317"
                     /note="Ribose/xylose/arabinose/galactoside ABC-type
                     transport systems, permease components [Carbohydrate
                     transport and metabolism]; Region: AraH; COG1172"
                     /db_xref="CDD:224093"
     misc_feature    <814987..815604
                     /locus_tag="Smed_4317"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    <814987..815595
                     /locus_tag="Smed_4317"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    815272..815328
                     /locus_tag="Smed_4317"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            815739..816707
                     /locus_tag="Smed_4318"
                     /db_xref="GeneID:5318893"
     CDS             815739..816707
                     /locus_tag="Smed_4318"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     KEGG: sme:SMb20671 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313056.1"
                     /db_xref="GI:150376460"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5318893"
                     /translation="MKRRDIMKLAAVAAVLAATTALMPAGDAVAQDKKFRIGFSQATT
                     IEPWRAQFNKDIIAEAAKHPDVELIITDGEDRTEKQVADVENLIRQEVDALLVSPKES
                     AGLTGVVQQAIDAKIPVFVLDRNVETDQYTQFVGGDNKLIGRAAGEYAVELLGGKGKA
                     QGNIVEIWGGMGTQPAHDRHDGFHEFTDKEPGIKNLLDKQSGDWKQDQAYNIMATALR
                     NNEKIDLVYGHNDPMAYGAYLAAKDAGREKEIKFIGIDALPNEGVTWVSNGELTATFL
                     YATPGAEGLRQAVKFLKGEKVEKTVTLDTLKVTEENAAQIMKDNGL"
     sig_peptide     815739..815831
                     /locus_tag="Smed_4318"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.924 at
                     residue 31"
     misc_feature    815805..816692
                     /locus_tag="Smed_4318"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     RbsB; COG1879"
                     /db_xref="CDD:224791"
     misc_feature    815844..816662
                     /locus_tag="Smed_4318"
                     /note="Periplasmic binding domain of two-component sensor
                     kinase signaling systems; Region: PBP1_sensor_kinase_like;
                     cd06308"
                     /db_xref="CDD:107303"
     misc_feature    order(815880..815882,816105..816107,816273..816275,
                     816504..816506,816564..816566)
                     /locus_tag="Smed_4318"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107303"
     gene            complement(816886..818166)
                     /locus_tag="Smed_4319"
                     /db_xref="GeneID:5319168"
     CDS             complement(816886..818166)
                     /locus_tag="Smed_4319"
                     /note="PFAM: type III effector Hrp-dependent outers;
                     KEGG: sme:SMb20670 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Hrp-dependent type III effector protein"
                     /protein_id="YP_001313057.1"
                     /db_xref="GI:150376461"
                     /db_xref="InterPro:IPR010737"
                     /db_xref="GeneID:5319168"
                     /translation="MTILLGSIADDYTGASDLANTLTKNGLRTVQTVGIPDPSLALPD
                     VDAVVVSLKIRSVAAEEAVAAALKAESWLRGRGAIHVLYKICSTFDSTDLGNIGPVTE
                     ALLSVSSGDIALVTPAFPETGRTVYLGHLFVNGQPLDESPLKDHPLNPMGDANLVRVL
                     ARQSRNRSGLVDLPAVAAGTDAVKARLGALRGEGVAAAIADAVFERDLETLGRVALEM
                     PVSTGASGLGLGLARALVSSGRASANTGANDAIRLPVGGLAAVLAGSCSVATLKQLEA
                     AERHMPVLRLDTEKLLAGQDDISAAIAWAGERIADGPVAIAASAAPDVVSRLQARYGR
                     EASGHAIETATAAIAGELVERGVRRLVVAGGETSGATVDRLAIPAFLIGPEIAPGVPL
                     LRTIGSAGNDMLLALKSGNFGGEDFFATALSMMR"
     misc_feature    complement(816889..818160)
                     /locus_tag="Smed_4319"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3395"
                     /db_xref="CDD:225930"
     gene            complement(818170..818946)
                     /locus_tag="Smed_4320"
                     /db_xref="GeneID:5319169"
     CDS             complement(818170..818946)
                     /locus_tag="Smed_4320"
                     /EC_number="5.3.1.22"
                     /note="PFAM: Xylose isomerase domain protein TIM barrel;
                     KEGG: sme:SMb20669 conserved hypothetical protein,
                     possibly hydroxypyruvate isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="YP_001313058.1"
                     /db_xref="GI:150376462"
                     /db_xref="InterPro:IPR012307"
                     /db_xref="GeneID:5319169"
                     /translation="MPVFAANLTMMFNEWTFLDRFDAAAEAGFTAVEYLFPYEVPPEA
                     IAERLIRNRLEQALFNLPPGDWVAGERGIAALPGRFDELKSGVDKALYYAAATGAKRL
                     HLMAGLSDPSDPEAASCYRRSIAYTAGRLAEKSIDLLIEPINGRNMPGYFLDDFAKAE
                     RLIAELALPNLKLQFDVYHRQIMHGDVAMALRHLLPVTGHIQIASVPSRHEPDGEELN
                     YSYLFEEIDRLGYDGHVGCEYFPRGSTLDGLAWFNPFRRS"
     misc_feature    complement(818173..818946)
                     /locus_tag="Smed_4320"
                     /note="Hydroxypyruvate isomerase [Carbohydrate transport
                     and metabolism]; Region: Hfi; COG3622"
                     /db_xref="CDD:226149"
     gene            complement(818958..819878)
                     /locus_tag="Smed_4321"
                     /db_xref="GeneID:5319170"
     CDS             complement(818958..819878)
                     /locus_tag="Smed_4321"
                     /EC_number="1.1.1.31"
                     /note="PFAM: 6-phosphogluconate dehydrogenase NAD-binding;
                     3-hydroxyacyl-CoA dehydrogenase NAD-binding; NAD-dependent
                     glycerol-3-phosphate dehydrogenase domain protein;
                     KEGG: sme:SMb20668 3-hydroxyisobutyrate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="YP_001313059.1"
                     /db_xref="GI:150376463"
                     /db_xref="InterPro:IPR002204"
                     /db_xref="InterPro:IPR006115"
                     /db_xref="InterPro:IPR006176"
                     /db_xref="InterPro:IPR011128"
                     /db_xref="GeneID:5319170"
                     /translation="MEESKMASKIAVLGLGSMGFGMARSMTRAGLDVSGYDVAPAAVE
                     RFVAEGGHGAGSPGEAVKGADIVVSVVVSGAQTEAVLFGPDGVAGAMKPGAVLVSSAT
                     MDPSIARDLAKRIESLGLHYLDAPISGGAAKAATGELTIMASGPPQAFAAARPALDCM
                     AAKVYELGEAAGIGAAFKMINQLLAGVHIAAACEAIAFAAKQGLDLDKVYEVITASAG
                     NSWMFQNRIPHVLAGDYTPLSAVEIFVKDLGIVQDMARAERYPVPLVAAALQMYLAAS
                     GAGMGRDDDSTLARLYAQLSGAQLPGKDKP"
     sig_peptide     complement(819789..819878)
                     /locus_tag="Smed_4321"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.611) with cleavage site probability 0.231 at
                     residue 30"
     misc_feature    complement(819000..819857)
                     /locus_tag="Smed_4321"
                     /note="3-hydroxyisobutyrate dehydrogenase and related
                     beta-hydroxyacid dehydrogenases [Lipid metabolism];
                     Region: MmsB; COG2084"
                     /db_xref="CDD:224995"
     misc_feature    complement(<819396..819854)
                     /locus_tag="Smed_4321"
                     /note="6-phosphogluconate dehydrogenase-like protein;
                     Reviewed; Region: PRK09599"
                     /db_xref="CDD:236582"
     gene            820012..821016
                     /locus_tag="Smed_4322"
                     /db_xref="GeneID:5319171"
     CDS             820012..821016
                     /locus_tag="Smed_4322"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: sme:SMb20667 putative transcriptional regulator,
                     LacI family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein LacI"
                     /protein_id="YP_001313060.1"
                     /db_xref="GI:150376464"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5319171"
                     /translation="MVIDFKQRTTVTLAEVAAAAGVGESTVSRVLRNHGSFSPKARER
                     VLDAVERLGYVPNRIAGTLASAGSRLVAFVIPSLTNIVFPDVLRGAGGVLEENHYQAV
                     FSVTDYDSEREETLVSAMLAWRPTAVMLAGFEHTEGTLKILRASGCRVVELLDTDGTA
                     ADLAVGFSNRQAGRASAEFLLRRGYRRLGYVGHDLDLDTRAGKRFTGFCEALNLAGSR
                     LAGREIRAGASSVESGRAGLKQLLERAPGLDAVYFSNDDMALGGYFHCLSNGIAVPAD
                     LALFGHNGLDIGQAIPQPLASIRTPRVATGKLAAELVINEAPPQVADLGFELIEGATA
                     "
     misc_feature    820096..821010
                     /locus_tag="Smed_4322"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    <820096..820206
                     /locus_tag="Smed_4322"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(820096..820098,820105..820107,820120..820125,
                     820132..820134,820171..820173,820180..820182,
                     820189..820194,820198..820203)
                     /locus_tag="Smed_4322"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    820171..820200
                     /locus_tag="Smed_4322"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    820219..821010
                     /locus_tag="Smed_4322"
                     /note="Ligand-binding domain of DNA transcription
                     repressor GntR specific for gluconate, a member of the
                     LacI-GalR family of bacterial transcription regulators;
                     Region: PBP1_GntR; cd01575"
                     /db_xref="CDD:107260"
     misc_feature    order(820219..820221,820258..820266,820273..820278,
                     820282..820287,820306..820320,820324..820326,
                     820357..820359,820366..820368,820375..820383,
                     820705..820707,820789..820791,820801..820803,
                     820810..820815)
                     /locus_tag="Smed_4322"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:107260"
     misc_feature    order(820255..820260,820267..820269,820402..820404,
                     820471..820473,820510..820512,820621..820623,
                     820696..820698,820858..820860,820909..820911)
                     /locus_tag="Smed_4322"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107260"
     gene            821032..821709
                     /locus_tag="Smed_4323"
                     /db_xref="GeneID:5319172"
     CDS             821032..821709
                     /locus_tag="Smed_4323"
                     /note="PFAM: class II aldolase/adducin family protein;
                     KEGG: sme:SMb20666 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative aldolase"
                     /protein_id="YP_001313061.1"
                     /db_xref="GI:150376465"
                     /db_xref="InterPro:IPR001303"
                     /db_xref="GeneID:5319172"
                     /translation="MSDTRLREEICRYGRSLFERGLTPGSSGNISMRLDDGGWLVTPT
                     NASLGFLDPGRISRLDAGGRLVSGDKPTKEIPLHSALYESRGSARAIVHLHSTHAVAL
                     TMLPEIDPRAALPPMTPYYLMRAGETALVPYYRPGDPAVADAIRGLAGKYSSVLLANH
                     GPVVAGDSLEAAVFATEELEETAKLYLLLRNLNPRYLSPQQVLDLASTFKLDLPSLDD
                     HEGHDHG"
     misc_feature    821032..821670
                     /locus_tag="Smed_4323"
                     /note="putative aldolase; Validated; Region: PRK08130"
                     /db_xref="CDD:181241"
     misc_feature    order(821065..821067,821077..821079,821101..821103,
                     821170..821172,821176..821181,821314..821316,
                     821320..821325,821338..821346,821383..821385,
                     821389..821394,821428..821430,821506..821508,
                     821539..821541,821560..821562,821572..821574)
                     /locus_tag="Smed_4323"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238232"
     misc_feature    order(821116..821118,821161..821166,821245..821253,
                     821308..821310,821314..821316,821509..821511)
                     /locus_tag="Smed_4323"
                     /note="active site"
                     /db_xref="CDD:238232"
     misc_feature    order(821308..821310,821314..821316,821509..821511)
                     /locus_tag="Smed_4323"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238232"
     gene            821950..822732
                     /locus_tag="Smed_4324"
                     /db_xref="GeneID:5319173"
     CDS             821950..822732
                     /locus_tag="Smed_4324"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb20664 putative transcriptional regulator,
                     GntR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001313062.1"
                     /db_xref="GI:150376466"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5319173"
                     /translation="MIGSPILTQMPKVGRSLERRTARELIADKLMVLVATNMLRPGDV
                     LPGERELANVLHVSRETVRGAIQTLAARGVVEVSQGSRTRVGNIDLSHLTVTIASPSA
                     IDSYDIEDVHAARLHIELKVVGDAAENIDEETLGKLGALLDAQKLCSDDAMRFLICDR
                     EFHVAIYRACGNPLLSDFVTDLYTYMMDHRRSAMSRPGAIDASYKDHSDIVAALRRRD
                     RAAVVAAFHHHLIRIYDTTKTLLANEEASGGKPKQKAPAGQG"
     misc_feature    821986..822687
                     /locus_tag="Smed_4324"
                     /note="Transcriptional regulators [Transcription]; Region:
                     FadR; COG2186"
                     /db_xref="CDD:225097"
     misc_feature    822010..822204
                     /locus_tag="Smed_4324"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    order(822010..822012,822016..822018,822085..822087,
                     822091..822096,822118..822132,822136..822141,
                     822148..822150,822178..822183,822187..822198)
                     /locus_tag="Smed_4324"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    822277..822579
                     /locus_tag="Smed_4324"
                     /note="FCD domain; Region: FCD; pfam07729"
                     /db_xref="CDD:219539"
     gene            822767..823750
                     /locus_tag="Smed_4325"
                     /db_xref="GeneID:5319174"
     CDS             822767..823750
                     /locus_tag="Smed_4325"
                     /note="PFAM: NAD-dependent epimerase/dehydratase;
                     short-chain dehydrogenase/reductase SDR; 3-beta
                     hydroxysteroid dehydrogenase/isomerase;
                     dTDP-4-dehydrorhamnose reductase; Male sterility domain;
                     KEGG: sme:SMb20663 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="YP_001313063.1"
                     /db_xref="GI:150376467"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5319174"
                     /translation="MHVMVIGAAGMIGRKLVERLAEEPVSLGREIARLTLVDVVEPPA
                     PPVFSTISTPLSVDLSDEGSAERLVSSRPDVIFHLAAIVSGEAEADFDKGYRVNLDGT
                     RALFEAIRREGQRERYVPRVLFASSIAVFGQPFPEKIDDAFFTTPLTSYGTQKAICEL
                     LLADYTRRGFFDGIGIRLPTICIRPGKPNKAASGFFSNILREPLSGQEAVLPVEENVR
                     HWFASPRSAVGFFIHAARMDTSIIGPRRNLTMPGLSALVGEEIEALGRIAGQKAVSLI
                     RREPDPVIREIVSGWATDFDARRARELGFTAESNFDEIIRIHIEDELGGRI"
     misc_feature    822767..823735
                     /locus_tag="Smed_4325"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    822767..823711
                     /locus_tag="Smed_4325"
                     /note="Escherichia coli Gne (a
                     nucleoside-diphosphate-sugar 4-epimerase)-like, extended
                     (e) SDRs; Region: Gne_like_SDR_e; cd05238"
                     /db_xref="CDD:187549"
     misc_feature    order(822785..822787,822791..822802,822872..822880,
                     823001..823009,823055..823057,823139..823147,
                     823217..823219,823229..823231,823298..823309)
                     /locus_tag="Smed_4325"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187549"
     misc_feature    order(823058..823060,823145..823147,823217..823219,
                     823229..823231)
                     /locus_tag="Smed_4325"
                     /note="active site"
                     /db_xref="CDD:187549"
     misc_feature    order(823145..823147,823217..823219,823304..823306,
                     823361..823363,823397..823399)
                     /locus_tag="Smed_4325"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187549"
     gene            823752..824528
                     /locus_tag="Smed_4326"
                     /db_xref="GeneID:5319175"
     CDS             823752..824528
                     /locus_tag="Smed_4326"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR; KR
                     domain protein;
                     KEGG: sme:SMb20662 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001313064.1"
                     /db_xref="GI:150376468"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5319175"
                     /translation="MAQANGSGDGKIALVTGGGTGVGRGIAEALSAEGYSIVVTGRRP
                     DVLDAAAAEIAGRTGGTVRAIVCDVGNPDQVADLFAAVRTEFGRLDLLVNNAGSNVPP
                     VPLEEVTFKQWNGIVAANLTGAFLCTQHAFRLMKTQTPRGGRIINNGSISAQTPRPNS
                     APYTATKHAITGLTKSTALDGRMHDVACGQIDIGNAATDMTARMSTGVLQANGEVAAE
                     PTIPIGHIADAVVYMASLPLSANVLTMTVMATKMPLVGRG"
     misc_feature    823779..824456
                     /locus_tag="Smed_4326"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Validated; Region: fabG; PRK05653"
                     /db_xref="CDD:235546"
     misc_feature    823827..824468
                     /locus_tag="Smed_4326"
                     /note="classical (c) SDRs; Region: SDR_c; cd05233"
                     /db_xref="CDD:212491"
     misc_feature    order(823872..823880,823950..823958,824034..824042,
                     824106..824108,824193..824201,824238..824240,
                     824250..824252,824328..824339,824343..824348)
                     /locus_tag="Smed_4326"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:212491"
     misc_feature    order(824109..824111,824199..824201,824238..824240,
                     824250..824252)
                     /locus_tag="Smed_4326"
                     /note="active site"
                     /db_xref="CDD:212491"
     gene            824612..825679
                     /locus_tag="Smed_4327"
                     /db_xref="GeneID:5319176"
     CDS             824612..825679
                     /locus_tag="Smed_4327"
                     /note="PFAM: ABC transporter related; TOBE domain protein;
                     Transport-associated OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20661 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313065.1"
                     /db_xref="GI:150376469"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005116"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5319176"
                     /translation="MAGVDFVDVRKSFGAFPVIKGVNIEIEDGEFVILVGPSGCGKST
                     LLRMLAGLENITAGEIRIGDRVVNRLPPKDRDIAMVFQNYALYPHMTVADNMAFSLML
                     ASRPKSEIEKRVGVAAEILGLSKLLDRYPRQLSGGQRQRVAMGRAIVRDPQVFLFDEP
                     LSNLDAKLRVAMRAEIKELHQRLKTTTVYVTHDQIEAMTMADKIVVMHDGIVEQIGAP
                     LDLYDNPANLFVAGFIGSPAMNMIKGRLDPDNPRAFLTADGTALPVARAAASAHGRDL
                     VYGLRPEYMSLDPNGLPAEIAVIEPTGYETQLIARLGGHDVTCVFRERVIAKPGETIH
                     LAIDAAHVHLFDAATGRRLVD"
     misc_feature    824612..825670
                     /locus_tag="Smed_4327"
                     /note="glycerol-3-phosphate transporter ATP-binding
                     subunit; Provisional; Region: ugpC; PRK11650"
                     /db_xref="CDD:236947"
     misc_feature    824621..825259
                     /locus_tag="Smed_4327"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    824717..824740
                     /locus_tag="Smed_4327"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    order(824726..824731,824735..824743,824855..824857,
                     825083..825088,825185..825187)
                     /locus_tag="Smed_4327"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    824846..824857
                     /locus_tag="Smed_4327"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    825011..825040
                     /locus_tag="Smed_4327"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    825071..825088
                     /locus_tag="Smed_4327"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    825095..825106
                     /locus_tag="Smed_4327"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    825173..825193
                     /locus_tag="Smed_4327"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     misc_feature    825473..825643
                     /locus_tag="Smed_4327"
                     /note="TOBE domain; Region: TOBE; pfam03459"
                     /db_xref="CDD:202645"
     gene            825769..827073
                     /locus_tag="Smed_4328"
                     /db_xref="GeneID:5319177"
     CDS             825769..827073
                     /locus_tag="Smed_4328"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb20660 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313066.1"
                     /db_xref="GI:150376470"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5319177"
                     /translation="MPIKRRDFLATSAALAGVAGLGIRPSFAQAEPSYKPEEGASLRL
                     LRWTPFVKGDEDAWIANTKKFTETTGVEVRIDKESWEDIRPKAAVAANVGSGPDMVMC
                     WFDDAHQYPDKLVDVTELADYLGNKYGGWYDGLKGYASREGQFIAMPLAAIGNAVCYR
                     ESHMKAAGFSEFPKDTAGFLELCKALKAKGTPAGFPHGKAVGDGNNYAHWLLWSHGGK
                     MVDESGKVMINSPETLAAVNYAKSLYETFIPGTESWLDINNNRAFLAGQVSLTANGVS
                     LYYAAKKDPALAELAADIRTTNFPIGPVGQSVELHQTSSILLFKHSKYPEAAKAYLKF
                     MMEADQMNAWIEGSSAYCCQPLKAFADNPVWTSDPIHAPYARASETLRPNGYAGPLGY
                     ASAGVMADYVLVDMFASAVTGQATPEDAIVEAERRANRYYRV"
     misc_feature    825769..827067
                     /locus_tag="Smed_4328"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     sig_peptide     825769..825855
                     /locus_tag="Smed_4328"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.816 at
                     residue 29"
     misc_feature    825928..826791
                     /locus_tag="Smed_4328"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     gene            827174..828103
                     /locus_tag="Smed_4329"
                     /db_xref="GeneID:5318087"
     CDS             827174..828103
                     /locus_tag="Smed_4329"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20659 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313067.1"
                     /db_xref="GI:150376471"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318087"
                     /translation="MSITPSGKPSTTASLMQNNNVLGFLFMLPAAVFLICFLTYPLGL
                     GVWLGFTDTRIGRDGVFIGIENYTFLAEDSVFWLSVYNTLLYTFVASILKFVLGLWLA
                     LLLNENLPFKSFFRAIVLLPWVVPTVLSALAFWWIYDSQFSIISWSLMQLGIIDGPIN
                     FLGDPNNARASVIAANVWRGIPFVAISLLAGLQTIPASLQEAASLDGATSWQRFRYVT
                     LPMLTPIIAVVMTFSVLFTFTDFQLIYVLTKGGPVNATHLMATLSFQRGIPGGQLGEG
                     AAIAVAMIPFLLAAIMFSFFGLQRRKWQQGGQD"
     misc_feature    827219..828079
                     /locus_tag="Smed_4329"
                     /note="ABC-type spermidine/putrescine transport system,
                     permease component II [Amino acid transport and
                     metabolism]; Region: PotC; COG1177"
                     /db_xref="CDD:224098"
     misc_feature    827501..828025
                     /locus_tag="Smed_4329"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(827516..827527,827531..827560,827567..827572,
                     827576..827578,827702..827707,827714..827716,
                     827720..827722,827729..827734,827738..827740,
                     827750..827755,827762..827764,827813..827815,
                     827855..827860,827867..827869,827888..827899,
                     827906..827911,827954..827959,827987..827992,
                     827999..828004,828008..828013,828020..828025)
                     /locus_tag="Smed_4329"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(827534..827578,827888..827905)
                     /locus_tag="Smed_4329"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(827576..827578,827687..827689,827906..827908,
                     827948..827950,827957..827959,827987..827989)
                     /locus_tag="Smed_4329"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(827765..827803,827819..827824,827834..827836)
                     /locus_tag="Smed_4329"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            828117..829016
                     /locus_tag="Smed_4330"
                     /db_xref="GeneID:5318088"
     CDS             828117..829016
                     /locus_tag="Smed_4330"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb20658 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313068.1"
                     /db_xref="GI:150376472"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318088"
                     /translation="MNATTRTEDETLTDTAEGMSYLNRLPRRIVVLYLPMAVFVFVLL
                     FPFYWMAITAVKPNSQLTDYNNYSPFWVVSPTLDHIKYLLFETSYPGWLWNTMLVAVG
                     STILSLAASVFAAYAIERVRFTGARPVGLMIFLAYLVPPSILFIPLAFIVFKFGIYDS
                     KLALIFTYPTFLIPFCTWLLMGYFRSIPFELEESALVDGATRWQILVKIILPLAVPGL
                     ISAGIFAFTLSWNEFIYALTFIQSSENKTVPVGVLTELVRGDVFEWGALMAGALFGSL
                     PVVILYSFFVDYYVSSMTGAVKE"
     misc_feature    828171..829010
                     /locus_tag="Smed_4330"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    828393..828953
                     /locus_tag="Smed_4330"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(828441..828446,828453..828458,828471..828473,
                     828501..828512,828516..828545,828552..828557,
                     828561..828563,828624..828629,828633..828635,
                     828639..828641,828648..828653,828657..828659,
                     828669..828674,828681..828683,828732..828734,
                     828774..828779,828786..828788,828807..828818,
                     828828..828833,828870..828875,828903..828908,
                     828915..828920,828924..828929,828936..828941,
                     828948..828953)
                     /locus_tag="Smed_4330"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(828519..828563,828807..828818,828822..828827)
                     /locus_tag="Smed_4330"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(828561..828563,828609..828611,828828..828830,
                     828864..828866,828873..828875,828903..828905)
                     /locus_tag="Smed_4330"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(828684..828722,828738..828743,828753..828755)
                     /locus_tag="Smed_4330"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(829024..829683)
                     /locus_tag="Smed_4331"
                     /db_xref="GeneID:5318089"
     CDS             complement(829024..829683)
                     /locus_tag="Smed_4331"
                     /note="KEGG: sme:SMb20657 hypothetical membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313069.1"
                     /db_xref="GI:150376473"
                     /db_xref="GeneID:5318089"
                     /translation="MMAEWATYTLADFLMFSPRVYFRLVERYNQGLWPFQLVFIAGAL
                     AVLFATATDGRRARAAAMATLSVAWFFCAWQFLWLRYSTINWAMSYGTAAFMLQSGLL
                     LLAILWTDRAALPANSLRRRGGIGLMVFGLLAYPFLPLIAGRAPASAESFGTMPDPTA
                     AVTLGALVAFLSQKLWLLLPIPLLWCAFSALTLLAMEDFGAWAPFVVILTTFALLLVR
                     R"
     gene            complement(829718..830635)
                     /locus_tag="Smed_4332"
                     /db_xref="GeneID:5318090"
     CDS             complement(829718..830635)
                     /locus_tag="Smed_4332"
                     /note="PFAM: aldo/keto reductase;
                     KEGG: sme:SMb20656 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="YP_001313070.1"
                     /db_xref="GI:150376474"
                     /db_xref="InterPro:IPR001395"
                     /db_xref="GeneID:5318090"
                     /translation="MTITRRAVVRGLGIGMSMPFMARPAMSQAAGLMARSIPKTGEAL
                     PLVGLGTWITFNVGDDSVLMDECAAVIAAFFEGGGRMIDCSPMYGSSQPTIGHGLARI
                     GYPERLFSAEKVWISDTSGGAAQIEASREHWGVARFDLMQVHNLVSWDEHLPALFSMK
                     ASGRLRYVGITTSEGRRHREIEQVMASEPIDFVQITYNILDRAVEERILPLAQEKRVA
                     VIVNRPFRQGDLIRRFEDAPLPDWVAETGARSWAQFLLKFIISHPAVTCAIPATTRVD
                     HVRENLEAARGILPDEKLRKRMTAYVEAL"
     sig_peptide     complement(830552..830635)
                     /locus_tag="Smed_4332"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.996) with cleavage site probability 0.835 at
                     residue 28"
     misc_feature    complement(829760..830533)
                     /locus_tag="Smed_4332"
                     /note="Aldo-keto reductases (AKRs) are a superfamily of
                     soluble NAD(P)(H) oxidoreductases whose chief purpose is
                     to reduce aldehydes and ketones to primary and secondary
                     alcohols. AKRs are present in all phyla and are of
                     importance to both health and industrial...; Region:
                     Aldo_ket_red; cd06660"
                     /db_xref="CDD:119408"
     misc_feature    complement(829760..830497)
                     /locus_tag="Smed_4332"
                     /note="Aldo/keto reductase family; Region: Aldo_ket_red;
                     pfam00248"
                     /db_xref="CDD:215817"
     misc_feature    complement(order(829793..829798,829805..829807,
                     829820..829831,829880..829882,829955..829972,
                     830054..830056,830120..830125,830201..830206,
                     830297..830299,830372..830374,830387..830389,
                     830480..830488))
                     /locus_tag="Smed_4332"
                     /note="active site"
                     /db_xref="CDD:119408"
     misc_feature    complement(order(830204..830206,830297..830299,
                     830372..830374,830387..830389))
                     /locus_tag="Smed_4332"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:119408"
     gene            complement(831086..831391)
                     /locus_tag="Smed_4333"
                     /db_xref="GeneID:5318091"
     CDS             complement(831086..831391)
                     /locus_tag="Smed_4333"
                     /note="KEGG: sme:SMb20654 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313071.1"
                     /db_xref="GI:150376475"
                     /db_xref="GeneID:5318091"
                     /translation="MAARCGRRRFDAILKRIFFTIVTRAREPKQFLACSLRSRLEGRM
                     QRKFMPTDVFLRLEKEWQHMRHAKHNLEIEAVPANDQHPDGINELEPASAPRSAHRR"
     gene            832116..834053
                     /locus_tag="Smed_4334"
                     /db_xref="GeneID:5318092"
     CDS             832116..834053
                     /locus_tag="Smed_4334"
                     /note="TIGRFAM: asparagine synthase
                     (glutamine-hydrolyzing);
                     PFAM: glutamine amidotransferase class-II; asparagine
                     synthase;
                     KEGG: sme:SMb20652 putative asparagine synthetase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
                     /protein_id="YP_001313072.1"
                     /db_xref="GI:150376476"
                     /db_xref="InterPro:IPR000583"
                     /db_xref="InterPro:IPR001962"
                     /db_xref="InterPro:IPR006426"
                     /db_xref="GeneID:5318092"
                     /translation="MCGFGGYLGSIRDGKPLLERMTAAIGHRGPDEHGIFTTPGAGLG
                     HVRLSIVGLGDGQQPMSDSSGELTIAFNGEIFNYVELRDELRAKGRRLRTSSDTEVIL
                     HLYKEMGEECLSLLNGDFAFAIWDARRHRMVLARDRMGVRPLFHTMKGGTFYFASEVK
                     ALLEIPGLSAEIDPIALDQIFTLWAPIAPRTPFRGIHELEPGHLMVAHQSGITTRPYW
                     QLDYPDRDQRSAYTNENQAAEELRALLTEATRIRMRADVPVGAYLSGGLDSSIISALA
                     AGMTSQGLRTFSVTFDTAEHDESAFQEAMAAALGTEHRAVACRAGDIARDFPDVVRFT
                     EKPIIRTAPAPLYKLSDLVRETGLKVVLTGEGADEVFAGYDIFKEARVRRFCGRQPGS
                     RVRPHLFRKLYPYLPGLQQQSAEYVAAFFGAGDVALDDPLFSHRPRFKGTAATKMFFS
                     ADLRAELKGYDAAEELVGRLPTAFGRWHPLHQAQYLESRFLLPGYILSSQGDRMAMAH
                     GIEGRFPFLDHRLVEFAAKLPPEMKLKGLVEKHILREATKDLLPPAIGKRTKQPYRAP
                     DSHSFSGAGELDYVRSAMGEEAIAAGGLFNAKAVTKLYEKCQSRPASGFRDNAAFVGV
                     LSTQLWLQTFTGNSLRKAEAA"
     misc_feature    832116..833933
                     /locus_tag="Smed_4334"
                     /note="Asparagine synthase (glutamine-hydrolyzing) [Amino
                     acid transport and metabolism]; Region: AsnB; COG0367"
                     /db_xref="CDD:223444"
     misc_feature    832119..832772
                     /locus_tag="Smed_4334"
                     /note="Glutamine amidotransferases class-II (GATase)
                     asparagine synthase_B type.  Asparagine synthetase B
                     catalyses the ATP-dependent conversion of aspartate to
                     asparagine. This enzyme is a homodimer, with each monomer
                     composed of a  glutaminase domain and a...; Region: AsnB;
                     cd00712"
                     /db_xref="CDD:238364"
     misc_feature    order(832119..832121,832254..832256,832329..832337,
                     832404..832406)
                     /locus_tag="Smed_4334"
                     /note="active site"
                     /db_xref="CDD:238364"
     misc_feature    order(832158..832160,832182..832184,832191..832193,
                     832200..832214,832251..832253)
                     /locus_tag="Smed_4334"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238364"
     misc_feature    832866..833813
                     /locus_tag="Smed_4334"
                     /note="The C-terminal domain of Asparagine Synthase B.
                     This domain is always found associated n-terminal
                     amidotransferase domain. Family members that contain this
                     domain catalyse the conversion of aspartate to asparagine.
                     Asparagine synthetase B  catalyzes the...; Region:
                     Asn_Synthase_B_C; cd01991"
                     /db_xref="CDD:238949"
     misc_feature    order(832899..832907,832980..832988,833160..833162,
                     833202..833210)
                     /locus_tag="Smed_4334"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238949"
     misc_feature    order(832899..832907,832980..832988,833160..833162,
                     833202..833210)
                     /locus_tag="Smed_4334"
                     /note="Molecular Tunnel; other site"
                     /db_xref="CDD:238949"
     gene            834081..834347
                     /locus_tag="Smed_4335"
                     /db_xref="GeneID:5318093"
     CDS             834081..834347
                     /locus_tag="Smed_4335"
                     /note="KEGG: sme:SMb20651 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313073.1"
                     /db_xref="GI:150376477"
                     /db_xref="GeneID:5318093"
                     /translation="MTQTIKDKVRTFVIENFLFGDTAYELADDASLIENDIIDSTGVL
                     ELVAFIEDDFGIAMADADIVPQNLDSLARISAFIEAKGAVPVSA"
     misc_feature    834081..834323
                     /locus_tag="Smed_4335"
                     /note="Acyl carrier protein [Lipid metabolism / Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: AcpP; COG0236"
                     /db_xref="CDD:223314"
     gene            834375..835922
                     /locus_tag="Smed_4336"
                     /db_xref="GeneID:5318094"
     CDS             834375..835922
                     /locus_tag="Smed_4336"
                     /note="PFAM: AMP-dependent synthetase and ligase;
                     KEGG: sme:SMb20650 putative long-chain fatty-acid-CoA
                     ligase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-dependent synthetase and ligase"
                     /protein_id="YP_001313074.1"
                     /db_xref="GI:150376478"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="GeneID:5318094"
                     /translation="MRFEQFLIRNAAANGAKTALVTDRRRLSYAELDDLSTRLAAALA
                     ANGVKRNDRVLAFMDNCWEAAVAIFAILKAGATFSPINASTKADKLAYVIADCEAAAI
                     LTQAKLMPVVTEALALAPGYRPFIASAAAPGGRMPDGAASFEECLTAVPAAVSHGGID
                     IDLGMLIYTSGSTGRPKGVMMTHRNIDAASESITTYLRNTPEDIILNVLPLAFDYGLY
                     QLLMAVRLGATLVLEKSFAFPQAIFDRIRAEGVTGFPLVPTMAAMILQMRDLEPGFLP
                     SLRYLSNTAAALPPAHIARLRELFPGARLYSMYGLTECKRCTYLPPEELDRRPGSVGI
                     AIPNTEAFVVDDEGNRLPPGVPGELVIRGPHVMQGYWRNAAATERMLRSGPDPWERVL
                     YTGDLFRTDEEGFLYFVGRKDDIIKTRGEKVAPKEVETVLHAHPGVAEAVVIGVPDPV
                     LGAAIGALVVLSDPSVTEREIIRHCARHLEDFMVPKIVEFRAELPKTDTGKVSRRLAA
                     ETLEPAE"
     misc_feature    834375..835901
                     /locus_tag="Smed_4336"
                     /note="Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases
                     II [Lipid metabolism / Secondary metabolites biosynthesis,
                     transport, and catabolism]; Region: CaiC; COG0318"
                     /db_xref="CDD:223395"
     misc_feature    834447..>834686
                     /locus_tag="Smed_4336"
                     /note="Adenylate forming domain, Class I; Region:
                     AFD_class_I; cl17068"
                     /db_xref="CDD:247692"
     misc_feature    834852..835898
                     /locus_tag="Smed_4336"
                     /note="Uncharacterized subfamily of fatty acid CoA ligase
                     (FACL); Region: FACL_like_6; cd05922"
                     /db_xref="CDD:213289"
     misc_feature    order(834870..834872,834879..834896,834900..834905)
                     /locus_tag="Smed_4336"
                     /note="acyl-activating enzyme (AAE) consensus motif; other
                     site"
                     /db_xref="CDD:213289"
     misc_feature    order(834879..834881,835224..835229,835293..835310,
                     835560..835562,835596..835598,835605..835607,
                     835638..835640,835875..835877)
                     /locus_tag="Smed_4336"
                     /note="putative AMP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213289"
     misc_feature    order(834879..834881,834999..835004,835143..835145,
                     835149..835154,835161..835163,835224..835229,
                     835293..835310,835560..835562,835596..835598,
                     835605..835607,835629..835640,835818..835820)
                     /locus_tag="Smed_4336"
                     /note="putative active site [active]"
                     /db_xref="CDD:213289"
     misc_feature    order(834999..835001,835149..835154,835161..835163,
                     835224..835226,835629..835637,835800..835802,
                     835818..835820)
                     /locus_tag="Smed_4336"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:213289"
     gene            835919..836926
                     /gene="nadE"
                     /locus_tag="Smed_4337"
                     /db_xref="GeneID:5318095"
     CDS             835919..836926
                     /gene="nadE"
                     /locus_tag="Smed_4337"
                     /EC_number="6.3.1.5"
                     /note="catalyzes the formation of nicotinamide adenine
                     dinucleotide (NAD) from nicotinic acid adenine
                     dinucleotide (NAAD) using either ammonia or glutamine as
                     the amide donor and ATP; ammonia-utilizing enzymes include
                     the ones from Bacillus and Escherichia coli while
                     glutamine-utilizing enzymes include the Mycobacterial one;
                     forms homodimers"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD synthetase"
                     /protein_id="YP_001313075.1"
                     /db_xref="GI:150376479"
                     /db_xref="InterPro:IPR003694"
                     /db_xref="GeneID:5318095"
                     /translation="MNIRPDQNRLAFSADPLKIDEAAETDRIVAGLRAQLRSLRKRGL
                     VLGLSGGIDSSVSVALAVRAVGAKNVFCLFMPENDSDPESLRLGRLIAETFGVEAVVE
                     DIGPTLDAMGCYQRRDAFIRELVPEYGQGWASKIVIANALEGDGYNISSLVVQDPDGQ
                     QTKLRMPPSVYLGIVAATNMKQRTRKQIEYFHADRLNFAVLGTPNRLEYDQGFFVKNG
                     DGAADVKPIAHLYKSQVYALAAHLGIPEEIRRRPPTTDTYSLEQTQEEFYFSLPYDRM
                     DLCLFGLNSGFGADEVGRAAGLSSAQVERVWADITAKRKATRYLHLGPQLVEPVQEIE
                     H"
     misc_feature    835946..836920
                     /gene="nadE"
                     /locus_tag="Smed_4337"
                     /note="NAD synthetase; Reviewed; Region: nadE; PRK00876"
                     /db_xref="CDD:179150"
     misc_feature    835973..836881
                     /gene="nadE"
                     /locus_tag="Smed_4337"
                     /note="NAD+ synthase is a homodimer, which catalyzes the
                     final step in de novo nicotinamide adenine dinucleotide
                     (NAD+) biosynthesis, an amide transfer from either ammonia
                     or glutamine to nicotinic acid adenine dinucleotide
                     (NaAD). The conversion of NaAD to NAD...; Region:
                     NAD_synthase; cd00553"
                     /db_xref="CDD:238309"
     misc_feature    order(835997..836002,836009..836011,836018..836023,
                     836210..836221,836228..836233,836240..836245,
                     836444..836446,836456..836458,836465..836470,
                     836474..836482,836486..836494,836498..836503,
                     836564..836569,836576..836593,836600..836605,
                     836873..836875,836879..836881)
                     /gene="nadE"
                     /locus_tag="Smed_4337"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238309"
     misc_feature    order(836054..836065,836078..836080,836135..836143,
                     836441..836443,836453..836455,836462..836467,
                     836471..836473,836525..836527,836540..836542,
                     836555..836566,836573..836575,836678..836683,
                     836687..836689,836717..836719,836873..836878)
                     /gene="nadE"
                     /locus_tag="Smed_4337"
                     /note="NAD binding pocket [chemical binding]; other site"
                     /db_xref="CDD:238309"
     misc_feature    order(836057..836065,836075..836080,836138..836143,
                     836471..836473,836525..836527,836612..836614,
                     836675..836680)
                     /gene="nadE"
                     /locus_tag="Smed_4337"
                     /note="ATP binding pocket [chemical binding]; other site"
                     /db_xref="CDD:238309"
     misc_feature    order(836063..836065,836075..836077,836540..836542,
                     836678..836680)
                     /gene="nadE"
                     /locus_tag="Smed_4337"
                     /note="Mg binding site [ion binding]; other site"
                     /db_xref="CDD:238309"
     misc_feature    order(836162..836164,836666..836689,836699..836722)
                     /gene="nadE"
                     /locus_tag="Smed_4337"
                     /note="active-site loop [active]"
                     /db_xref="CDD:238309"
     gene            complement(837016..837315)
                     /locus_tag="Smed_4338"
                     /db_xref="GeneID:5318096"
     CDS             complement(837016..837315)
                     /locus_tag="Smed_4338"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313076.1"
                     /db_xref="GI:150376480"
                     /db_xref="GeneID:5318096"
                     /translation="MYLLGETHVTLSAHLRLNVERLLPHLLPPQRPEMIVSSGGNSMN
                     RNVIIGIIVLAIIILAVIFFMPGTAETPPATETPPATEPAPTEPAPAPTTPAPSQ"
     gene            837793..838044
                     /locus_tag="Smed_4339"
                     /db_xref="GeneID:5319209"
     CDS             837793..838044
                     /locus_tag="Smed_4339"
                     /note="KEGG: sme:SMb20647 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313077.1"
                     /db_xref="GI:150376481"
                     /db_xref="GeneID:5319209"
                     /translation="MRETQSIAVDLLAGTVDELYRKFGAWKTARALMTAVWRRRQAQN
                     QISHLSNRMRRDIGLPDAEEEFSVLDIGALGKVKAVRPD"
     gene            838320..839108
                     /gene="minC"
                     /locus_tag="Smed_4340"
                     /db_xref="GeneID:5319210"
     CDS             838320..839108
                     /gene="minC"
                     /locus_tag="Smed_4340"
                     /note="blocks the formation of polar Z-ring septums"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor"
                     /protein_id="YP_001313078.1"
                     /db_xref="GI:150376482"
                     /db_xref="InterPro:IPR005526"
                     /db_xref="InterPro:IPR013033"
                     /db_xref="GeneID:5319210"
                     /translation="MARLHLGNQKLTKMTKVLTDARSIRIKGRSFLALVLSPELPLDW
                     WLGRLDDLASRSAGFFLGRPVVLDVADLEIDRKQLKSLLEELGQRNVRVMGIEGGRPS
                     LFEPGMPPAMKGGRPAPDFEVPEANPAESPKAGKGKAAAPVITEEVQPVRATASIIVR
                     EPVRSGQSVIFPEGDVTVVGSVASGAEIVAGGSVHIYGTLRGRALAGSVGNASARIFC
                     RRLEAELLAIDGVYKTAEDMAPNLRGQSVQLWLEGDSIMAERLN"
     misc_feature    838359..839105
                     /gene="minC"
                     /locus_tag="Smed_4340"
                     /note="septum formation inhibitor; Reviewed; Region: minC;
                     PRK05177"
                     /db_xref="CDD:235357"
     misc_feature    838386..838670
                     /gene="minC"
                     /locus_tag="Smed_4340"
                     /note="Septum formation inhibitor MinC, N-terminal domain;
                     Region: MinC_N; pfam05209"
                     /db_xref="CDD:203206"
     misc_feature    838788..839102
                     /gene="minC"
                     /locus_tag="Smed_4340"
                     /note="Septum formation inhibitor MinC, C-terminal domain;
                     Region: MinC_C; pfam03775"
                     /db_xref="CDD:146423"
     gene            839204..840019
                     /locus_tag="Smed_4341"
                     /db_xref="GeneID:5319211"
     CDS             839204..840019
                     /locus_tag="Smed_4341"
                     /note="TIGRFAM: septum site-determining protein MinD;
                     PFAM: Cobyrinic acid ac-diamide synthase;
                     KEGG: sme:SMb21523 putative cell division inhibitor
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="YP_001313079.1"
                     /db_xref="GI:150376483"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR010223"
                     /db_xref="GeneID:5319211"
                     /translation="MAKVVVVTSGKGGVGKTTSTAALGAALAQRNEKTVVVDFDVGLR
                     NLDLVMGAERRVVYDLVNVIQGDAKLPQALIRDKRLDTLFLLPASQTRDKDSLTPEGV
                     ERVMAELRKHFDWIICDSPAGIERGATLAMRHADLAVIVTNPEVSSVRDSDRIIGLLD
                     AKTERAERGERVEKHLLLTRYDAVRAERGDMLKVDDVLEILSIPLIGIVPESMDVLKA
                     SNLGAPVTLADSRSAPALAYLDAARRLAGETVPMTIPGEKRGFLGKIFGRRAA"
     misc_feature    839288..840016
                     /locus_tag="Smed_4341"
                     /note="Septum formation inhibitor-activating ATPase [Cell
                     division and chromosome partitioning]; Region: MinD;
                     COG2894"
                     /db_xref="CDD:225447"
     misc_feature    839288..839884
                     /locus_tag="Smed_4341"
                     /note="Bacterial cell division requires the formation of a
                     septum at mid-cell. The site is determined by the min
                     operon products MinC, MinD and MinE. MinC is a nonspecific
                     inhibitor of the septum protein FtsZ. MinE is the
                     supressor of MinC. MinD plays a pivotal...; Region: MinD;
                     cd02036"
                     /db_xref="CDD:238993"
     misc_feature    839315..839323
                     /locus_tag="Smed_4341"
                     /note="Switch I; other site"
                     /db_xref="CDD:238993"
     misc_feature    839558..839572
                     /locus_tag="Smed_4341"
                     /note="Switch II; other site"
                     /db_xref="CDD:238993"
     gene            840016..840279
                     /gene="minE"
                     /locus_tag="Smed_4342"
                     /db_xref="GeneID:5319212"
     CDS             840016..840279
                     /gene="minE"
                     /locus_tag="Smed_4342"
                     /note="works in conjunction with MinC and MinD to enable
                     cell division at the midpoint of the long axis of the
                     cell"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="YP_001313080.1"
                     /db_xref="GI:150376484"
                     /db_xref="InterPro:IPR005527"
                     /db_xref="GeneID:5319212"
                     /translation="MSIFRFFSKQTSAPTARERLQVLLAHERASVGQSDLVAVLREEI
                     LAVIAKHVQVDRDKVNVTMERGEHVTTLEVDIEIPIKAGVRAA"
     misc_feature    840016..840252
                     /gene="minE"
                     /locus_tag="Smed_4342"
                     /note="cell division topological specificity factor MinE;
                     Reviewed; Region: minE; PRK00296"
                     /db_xref="CDD:234718"
     gene            840710..841183
                     /locus_tag="Smed_4343"
                     /db_xref="GeneID:5319213"
     CDS             840710..841183
                     /locus_tag="Smed_4343"
                     /note="KEGG: sme:SMb21521 hypothetical exported protein,
                     glycine-rich"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313081.1"
                     /db_xref="GI:150376485"
                     /db_xref="GeneID:5319213"
                     /translation="MVTRRNFLAALCGVSVGLPVALSPYKIVLSGSDIELELQAALAK
                     GGGSGGGRGGGGGNGGGRGGGNGGGNGGGNGGGRGNGNGRGGGSGGNSNSGRASGKAA
                     TSVEGGGSILRVRHRDGISEVIEGARYIMKDSRGRTIVNRRATSADRRRLLSFID"
     sig_peptide     840710..840775
                     /locus_tag="Smed_4343"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.944) with cleavage site probability 0.582 at
                     residue 22"
     gene            complement(841192..841851)
                     /locus_tag="Smed_4344"
                     /db_xref="GeneID:5319214"
     CDS             complement(841192..841851)
                     /locus_tag="Smed_4344"
                     /note="PFAM: regulatory protein LuxR; response regulator
                     receiver; Sigma-70 region 4 type 2;
                     KEGG: sme:SMb21520 putative two-component response
                     regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="two component LuxR family transcriptional
                     regulator"
                     /protein_id="YP_001313082.1"
                     /db_xref="GI:150376486"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR013249"
                     /db_xref="GeneID:5319214"
                     /translation="MMMGIRVAVIDDHPLFREGVSRSLSEIDGFEIVAEGGSRDEAIA
                     IARSHNPDVMLIDISMPGGGLNAIPAILTVAPSQKIVMLTVSEANDDVAAALKEGAKG
                     YILKGIGARALADVIRTVASGESYVAPTLSAKLLTGQLLNPAPAKSNLVAELTRREQE
                     VLHLVASGMSNKQIARKLDLHEKTVKHHMTQIMAKLNVANRTEAAMVLRDAVDWRPVS
                     Q"
     misc_feature    complement(841222..841839)
                     /locus_tag="Smed_4344"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    complement(841489..841827)
                     /locus_tag="Smed_4344"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(841531..841536,841543..841545,
                     841600..841602,841660..841662,841681..841683,
                     841816..841821))
                     /locus_tag="Smed_4344"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(841681..841683)
                     /locus_tag="Smed_4344"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(841660..841662,841663..841665,
                     841669..841674))
                     /locus_tag="Smed_4344"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(841528..841536)
                     /locus_tag="Smed_4344"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(841237..841392)
                     /locus_tag="Smed_4344"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(841249..841251,841282..841296,
                     841300..841305,841309..841314,841336..841344,
                     841381..841389))
                     /locus_tag="Smed_4344"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(841243..841251,841342..841344,
                     841348..841350,841354..841356))
                     /locus_tag="Smed_4344"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(841848..843248)
                     /locus_tag="Smed_4345"
                     /db_xref="GeneID:5319215"
     CDS             complement(841848..843248)
                     /locus_tag="Smed_4345"
                     /note="PFAM: ATP-binding region ATPase domain protein;
                     KEGG: sme:SMb21519 putative two-component sensor histidine
                     kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative signal transduction histidine kinase"
                     /protein_id="YP_001313083.1"
                     /db_xref="GI:150376487"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="GeneID:5319215"
                     /translation="MRADDLIRRWNSQPLARQFLIIGGSVAAAAMLVVSAFVTSLIEE
                     AVTRNSAATTALYVDSVIAPLLPDMQTTQVLDDSVARALDETLGQGALGDRLASFRLW
                     RADGTVLYSSEKAMVGQKFELGPELTTAFDGDMVARFMPLDEADGETERLSNSPLLEI
                     YNPLLQPWSGEVVAVSEFHEIADEFQQSLNRARLHTWLAVAGFTLAFFIALSAIVLRG
                     SRTIEKQRQALGQRVEELSALLAQNEALRGRLRQASQRATALNETLLRRIGADLHDGP
                     AQLVAYASLRLDSNKLVSPSTPEDVREREIAAIKGSLDEAMNEIRTLCSGLVLPQIET
                     AGLREILERCVRAHEQRTGTTVDLSMIGPPIRLSASAKICIYRFVQEALNNAYRHGGG
                     VAQRVTQSTNGDKITVEVADGGPGFDPGEVQPTSLGLAGLKGRVESLGGTFEINANAP
                     GTIVRMALGLEEMEQA"
     sig_peptide     complement(843138..843248)
                     /locus_tag="Smed_4345"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.794) with cleavage site probability 0.640 at
                     residue 37"
     misc_feature    complement(841869..842978)
                     /locus_tag="Smed_4345"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: COG4585"
                     /db_xref="CDD:226951"
     misc_feature    complement(842268..842453)
                     /locus_tag="Smed_4345"
                     /note="Histidine kinase; Region: HisKA_3; pfam07730"
                     /db_xref="CDD:219540"
     misc_feature    complement(841875..842126)
                     /locus_tag="Smed_4345"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(841887..841889,841893..841898,
                     841911..841913,841914..841916,841962..841973,
                     841998..842003,842007..842009,842013..842015,
                     842019..842021,842085..842087,842094..842096,
                     842106..842108))
                     /locus_tag="Smed_4345"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(842094..842096)
                     /locus_tag="Smed_4345"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(841965..841967,841971..841973,
                     842001..842003,842007..842009))
                     /locus_tag="Smed_4345"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            843534..844274
                     /locus_tag="Smed_4346"
                     /db_xref="GeneID:5319216"
     CDS             843534..844274
                     /locus_tag="Smed_4346"
                     /note="KEGG: sme:SMb21518 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313084.1"
                     /db_xref="GI:150376488"
                     /db_xref="GeneID:5319216"
                     /translation="MPVSKIVGRGLIALALAGAPLAGVAPGMSDIAFAKGGNGNGGGN
                     GGGGGNGGGGGNGGGHGKSGSQGSHGKSGSHTKARADSGKSGGERAGTPRFLQGLFKQ
                     GKKAERPTTGKAVKAAKANAIAKAVPTPKPKNPQAEMAKLSSLGRNYHAYLNSNDPRM
                     AAISAYAIAYAEFEAEFGSDVIPTDPALSDEALREAIASFTNGGEVTDATLEDVKETL
                     GVGSSVGKIDQIREHLLDTTDDEVIMTE"
     sig_peptide     843534..843602
                     /locus_tag="Smed_4346"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.971) with cleavage site probability 0.555 at
                     residue 23"
     gene            844298..845098
                     /locus_tag="Smed_4347"
                     /db_xref="GeneID:5319217"
     CDS             844298..845098
                     /locus_tag="Smed_4347"
                     /note="PFAM: EAL domain protein;
                     KEGG: sme:SMb21517 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate phosphodiesterase"
                     /protein_id="YP_001313085.1"
                     /db_xref="GI:150376489"
                     /db_xref="InterPro:IPR001633"
                     /db_xref="GeneID:5319217"
                     /translation="MDHLRRFNHVVGAVTQAMREGRLGFSLQQVNPIDEAGAVFYSQC
                     LGRLVERDGEVRTSDEFTAFLEASGRVASYDRYMVGLALEWLECNPSHVLGCKISTGN
                     IFDEHAWSEFHDLLSRNREMAPRLVLEISESLPLATLPTAVAFLEGVRALGCKIALDS
                     FGTGHSTPESLLSFSVDIVKLDAFFIGRGGKDFLHHLVGLASCVAPMVVVEGVETYAQ
                     FEVAKRAGATHVQGFLLSEPTLYPVYCGQPAPPLAALHSTAGYRQLHS"
     misc_feature    844331..845011
                     /locus_tag="Smed_4347"
                     /note="EAL domain. This domain is found in diverse
                     bacterial signaling proteins. It is called EAL after its
                     conserved residues and is also known as domain of unknown
                     function 2 (DUF2).  The EAL domain has been shown to
                     stimulate degradation of a second...; Region: EAL;
                     cd01948"
                     /db_xref="CDD:238923"
     gene            845260..845991
                     /locus_tag="Smed_4348"
                     /db_xref="GeneID:5319218"
     CDS             845260..845991
                     /locus_tag="Smed_4348"
                     /note="PFAM: ErfK/YbiS/YcfS/YnhG family protein;
                     KEGG: sme:SMb21516 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ErfK/YbiS/YcfS/YnhG family protein"
                     /protein_id="YP_001313086.1"
                     /db_xref="GI:150376490"
                     /db_xref="InterPro:IPR005490"
                     /db_xref="GeneID:5319218"
                     /translation="MFSKMQLQRRTFLLGAMSATAALAGCTTSMPATERAPVPRLVSR
                     PLGLPGDAELEARYAAVEDGGHLIPAVPYRQMDPKYLRQRVPDPTGEPAGTVVVDTPG
                     RYLYLVEPGGTAMRYGVGIGREGFAWEGDGIIHWRQAWPRWKPPAEMIARRPELAEYS
                     VENGGMAPGIKNPLGARALYIFQNGRDTLYRLHGTPEWNSIGKATSSGCVRLVNQDVI
                     DLYKRVPYHARIVVYQTPLIAQGQA"
     sig_peptide     845260..845364
                     /locus_tag="Smed_4348"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.408 at
                     residue 35"
     misc_feature    845272..845967
                     /locus_tag="Smed_4348"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: ErfK; COG1376"
                     /db_xref="CDD:224294"
     misc_feature    <845809..845955
                     /locus_tag="Smed_4348"
                     /note="L,D-transpeptidase catalytic domain; Region: YkuD;
                     pfam03734"
                     /db_xref="CDD:217702"
     gene            complement(845994..847109)
                     /locus_tag="Smed_4349"
                     /db_xref="GeneID:5318198"
     CDS             complement(845994..847109)
                     /locus_tag="Smed_4349"
                     /note="KEGG: sme:SMb21515 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313087.1"
                     /db_xref="GI:150376491"
                     /db_xref="GeneID:5318198"
                     /translation="MSQIRSLAAEDIPAVARLFQKVFRNREEEPPAAFVAYLRRLYVD
                     APGTDPDIRPLVHVNDDGRVSGFVGANTLPMTYRGRRLRAAICGSLMVEGREGDPMAG
                     ARLLKAFLAGPQDLSFSETASEVSTQMWTKLRGIVLPQYSLDWVRVIRPASFALDLVA
                     SRLRPVRALVPLAHAFDRRYRGKMGRGELRWSGVPAAATTQGSLQVAEIDRHGFAELF
                     APLTRQFAIQPAWAESQLEHILEDAEKKPLFGEPVFAALKTRSGAPVGAFFYHLQPGG
                     TARVLQVLALSGQAGPVLDCLIEHAAGRGAAAVRGRTQPALLEAMMGRRIGFVHAAST
                     VVHSREEELVDAFRHAQGFINGLAGEHWSRLIGSRFE"
     misc_feature    complement(<846855..847103)
                     /locus_tag="Smed_4349"
                     /note="N-Acyltransferase superfamily: Various enzymes that
                     characteristically catalyze the transfer of an acyl group
                     to a substrate; Region: NAT_SF; cl17182"
                     /db_xref="CDD:247736"
     gene            complement(847106..847948)
                     /locus_tag="Smed_4350"
                     /db_xref="GeneID:5318199"
     CDS             complement(847106..847948)
                     /locus_tag="Smed_4350"
                     /note="TIGRFAM: modification methylase, HemK family;
                     PFAM: putative RNA methylase; methyltransferase small;
                     KEGG: sme:SMb21514 putative modification methylase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="HemK family modification methylase"
                     /protein_id="YP_001313088.1"
                     /db_xref="GI:150376492"
                     /db_xref="InterPro:IPR000241"
                     /db_xref="InterPro:IPR002052"
                     /db_xref="InterPro:IPR004556"
                     /db_xref="InterPro:IPR007848"
                     /db_xref="GeneID:5318199"
                     /translation="MLLPSIRRREPPSFQLPFTSTRYCAPERSPTPTTEGAFVLQGDN
                     HLDGRTEGRAPRLVHFMDIDLELAPGVLVPREETELLGRTAAAILREAARPATVVDMC
                     CGSGNLALGIAAEVPLARVWGADLTDSTVALARRNVERLALGDRVFVRQGDLFAALAG
                     EGLEEAVDMIVCNPPYISTSRLESDSAHLLASEPREAFDGGPYGISIHQRLIREAVAF
                     LKPGGWLLFEFGEGQDRQTAALLARTKAYDAVSFATDAAGKPRVARVRRLAGPTAAAD
                     WEIR"
     misc_feature    complement(847139..847660)
                     /locus_tag="Smed_4350"
                     /note="Methyltransferase domain; Region: Methyltransf_31;
                     pfam13847"
                     /db_xref="CDD:222415"
     misc_feature    complement(847262..847660)
                     /locus_tag="Smed_4350"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(847430..847432,847481..847489,
                     847571..847576,847628..847648))
                     /locus_tag="Smed_4350"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            848098..849405
                     /locus_tag="Smed_4351"
                     /db_xref="GeneID:5318200"
     CDS             848098..849405
                     /locus_tag="Smed_4351"
                     /note="PFAM: polysaccharide biosynthesis protein;
                     KEGG: sme:SMb21513 putative cell-surface polysaccharide
                     exporter protein, PST family"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="YP_001313089.1"
                     /db_xref="GI:150376493"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="GeneID:5318200"
                     /translation="MATDGVTEQRGYKPFLPMLMSYVASGGSLVLGSAAQLLTFAILA
                     RWLGVHEFSVFVAITAVANIAVHLCGLGAMECLVRRVARDRAIYPQMLGHNIILTSGS
                     GAALVLLGAVVLPFFFTLSPDRMTNVAVITLMLVTNILLVRVIVLTEQIFIAHTDFAS
                     ANKVVVGFAAARTVAAALACIAFGATTVASWAVWQFLCHVLVAVCCMWSVRLLGAPSY
                     RLVREELPQGLYFSIPFILRALRQNADLLVLSLVTTAEIVASYSVARRILESSYLSVE
                     ALNRLIYPGSARATAAGLHHALQRVRRVLAAATVISLAAAVTVFVLAPILPYLFGKEY
                     LSLVGFARTLCWVVVPLAMWSVAVEALGASGDHAARAAVMGFGSIAGTGLAAWASWYA
                     PPAGTFISFYVIEIAMVVASWSVFLHFVRRDRQAAITFGSGSA"
     misc_feature    848170..849402
                     /locus_tag="Smed_4351"
                     /note="Membrane protein involved in the export of
                     O-antigen and teichoic acid [General function prediction
                     only]; Region: RfbX; COG2244"
                     /db_xref="CDD:225153"
     misc_feature    848194..848964
                     /locus_tag="Smed_4351"
                     /note="Polysaccharide biosynthesis protein; Region:
                     Polysacc_synt_3; pfam13440"
                     /db_xref="CDD:222131"
     gene            849402..850550
                     /locus_tag="Smed_4352"
                     /db_xref="GeneID:5318201"
     CDS             849402..850550
                     /locus_tag="Smed_4352"
                     /note="KEGG: sme:SMb21512 hypothetical membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313090.1"
                     /db_xref="GI:150376494"
                     /db_xref="GeneID:5318201"
                     /translation="MTIEVEEIRASENIPAGAGPRRNIRPMTPGDVPAVGRLFNRIFR
                     GHDRAPGDDLGRYIETVFFGSPQYHPDLGSVVHENAAGGIDSAILSVPMAFMVNGHPI
                     TARLLCAFMAESKAGAVGAARLARSMRAARQDMCFSDNASPVSADHWAAGGGLVLPIQ
                     SLEWQRSFLPLTAAAILASRHLPVVGSPILLGILGLVDRALRRLRPSMRPKAEGACRI
                     EPAGVEEFLECAMPMLERFAIRPAWSKSEFDWLVHIASMNRSLGALECRKVVLADGRT
                     IGAFLFFRKPTGIATVLNLVTEEGRERDVAAAMFARLDAEGYALAVGMAQPFLMNAIS
                     RQRWLSFRHRGYFCLVTRHAELRQAAERNDIYIGGLASETWSRLLTDF"
     gene            850833..852446
                     /locus_tag="Smed_4353"
                     /db_xref="GeneID:5318202"
     CDS             850833..852446
                     /locus_tag="Smed_4353"
                     /note="PFAM: lipopolysaccharide biosynthesis protein;
                     KEGG: sme:SMb21506 putative auxiliar protein involved in
                     export of cell surface polysaccharides, MPA1 family
                     without cytosolic domain, slightly ExoP-like"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="YP_001313091.1"
                     /db_xref="GI:150376495"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="GeneID:5318202"
                     /translation="MYRRSEPEGQGLRHGRPSQRLRPAGGSLLDFVPASAEETAPPEE
                     ARTLEKVGASVRVVDLPAPSHNARAPEEPASAADFFPQLHLLGSIGINDIIVWLRDGI
                     RWIVIALLLSGAAAFAYAVTATPRYTVYTDLVVDPSNLNVVSDDVFTTNPQRDAQLLE
                     VESKLRILTSRNVLQRVIDELRLSEDPEFVKPTLLDWLKALLAPRDGKTDKDLAAMRV
                     LSERVEARREERSFVVVLKVWSEEPAKAIALSDAIVEAFEAELFQSSAESAGRVAQNL
                     NARLDELRRNVTEAERRVEDFRRQNGLQSTNGELVSNQLSSELNTQVLDGQQRFIQAE
                     TRYRQMSSAVAGGRTASASVFESANMTDLRQQYNALQQQIGSMQLTYGERHPRLVAAR
                     SERATLETAMKDEARRILERAKADFDRERKALATLRGKADNEKSNVFTDNQAQVQLRD
                     LERDARSKAAIYETHLARAQQITERQQIDTTNVRVISRALPPNARSWPPRTLVLLIGG
                     AFLGLALGIATALALGLWRFLRGKTRAAA"
     misc_feature    851073..852335
                     /locus_tag="Smed_4353"
                     /note="Uncharacterized protein involved in
                     exopolysaccharide biosynthesis [Cell envelope biogenesis,
                     outer membrane]; Region: GumC; COG3206"
                     /db_xref="CDD:225747"
     misc_feature    851091..>851396
                     /locus_tag="Smed_4353"
                     /note="Chain length determinant protein; Region: Wzz;
                     pfam02706"
                     /db_xref="CDD:217194"
     misc_feature    852165..>852335
                     /locus_tag="Smed_4353"
                     /note="G-rich domain on putative tyrosine kinase; Region:
                     GNVR; pfam13807"
                     /db_xref="CDD:222392"
     gene            852461..853792
                     /locus_tag="Smed_4354"
                     /db_xref="GeneID:5318203"
     CDS             852461..853792
                     /locus_tag="Smed_4354"
                     /note="PFAM: O-antigen polymerase;
                     KEGG: sme:SMb21505 putative membrane protein, similar to
                     Wzy-like polysaccharide polymerase ExoQ"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="YP_001313092.1"
                     /db_xref="GI:150376496"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="GeneID:5318203"
                     /translation="MDRGSYAEAERTSGSTARVGTALFIAIFLFFWISINPFVDLTGE
                     AVLDPSAGNSNRLNQIISLLLFAGMLCYGLIHPLRETILRPRLLLAILYCWFIVVSLI
                     SAHPMLGIKGVILSVMVTVNASIYLLLPTSERHFARMLGIAILVMLSVAYYGIVFNPS
                     LAIHQATELREPMNAGLWRGHFPHKNSAAAAMVIAAFIGLFVMNAWSRVAGIAIVALS
                     FVFLVNTGGKTSTAMLPAILLVAFLFEKVRFLRIPIAVGGVGLFNLFAVGSAVIVPLG
                     EFINGLGVDATFTNRADIWRFAFGALAEQPLTGYGFKAFWQTEELVYSGGTVETWAVA
                     AANGHNSYLDIALMTGFPGLALTLIWILFLPLRNIARIAPEREHTHLTRLFVRIWLYT
                     IFNAGLESLFFEGGSLLWFTFMVALYGLSLQSSAELAAVPARAREGRLVHA"
     misc_feature    852572..853732
                     /locus_tag="Smed_4354"
                     /note="Lipid A core - O-antigen ligase and related enzymes
                     [Cell envelope biogenesis, outer membrane]; Region: RfaL;
                     COG3307"
                     /db_xref="CDD:225844"
     misc_feature    853082..853543
                     /locus_tag="Smed_4354"
                     /note="O-antigen ligase like membrane protein; Region:
                     O-antigen_lig; pfam13425"
                     /db_xref="CDD:222119"
     gene            853785..854540
                     /locus_tag="Smed_4355"
                     /db_xref="GeneID:5318204"
     CDS             853785..854540
                     /locus_tag="Smed_4355"
                     /note="PFAM: polysaccharide deacetylase;
                     KEGG: sme:SMb21504 putative protein, slightly similar to
                     carbohydrate deacetylase"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="YP_001313093.1"
                     /db_xref="GI:150376497"
                     /db_xref="InterPro:IPR002509"
                     /db_xref="GeneID:5318204"
                     /translation="MLERQSRIGPLVDRLANRAIWKLARSRRLLETDVPLVSFTFDDV
                     PDSALGAGAAVLEKYEARGTFYIAGGLAGQVEPDRRLITPEGCGELLARGHEIGCHTF
                     SHRRLRDIAGLGADLDRNDAYLKRVGVSPGASNFAFPYNAAWPSARAELRRRYRTCRA
                     AGEAINRGAVDPMMLKGVEIRQPEHEARALTSWIDDVVERPGWLIFFTHDIAMQPTSY
                     GCTPETFDHLVRYAVEKGCCILRVDSAADRIGW"
     misc_feature    853785..854537
                     /locus_tag="Smed_4355"
                     /note="Predicted xylanase/chitin deacetylase [Carbohydrate
                     transport and metabolism]; Region: CDA1; COG0726"
                     /db_xref="CDD:223798"
     misc_feature    853893..854486
                     /locus_tag="Smed_4355"
                     /note="Putative catalytic NodB homology domain of gellan
                     lyase and similar proteins; Region: CE4_GLA_like_6s;
                     cd10967"
                     /db_xref="CDD:200589"
     misc_feature    order(853908..853913,854082..854084,854094..854096,
                     854199..854207,854409..854411)
                     /locus_tag="Smed_4355"
                     /note="putative active site [active]"
                     /db_xref="CDD:200589"
     misc_feature    order(853911..853913,854082..854084,854094..854096)
                     /locus_tag="Smed_4355"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:200589"
     gene            854551..855780
                     /locus_tag="Smed_4356"
                     /db_xref="GeneID:5318205"
     CDS             854551..855780
                     /locus_tag="Smed_4356"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21503 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313094.1"
                     /db_xref="GI:150376498"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318205"
                     /translation="MTRKRLLAINNYFYRRGGAEAVFFDHMSMFGEIGWDIVPFAMQH
                     DLNEPSPWSDYFVSEIEYGRRTGLLRKAVQAASVIYSLEAQRNLGRLIERARPAVAHA
                     HNVYHHLSPAIFSTLKAAGIPVVMTVHDLKLACPSYKMLRDGKVCEDCRGGRVYNVLR
                     HRCVKGSAPLSAVVLAETLLHRLLGLYRDKVDRLVVPSRFYLEKLAEWGWPREKMVHI
                     ANFVDVTNLSVHRQESDYFAFAGRLAPEKGLTTLIRAVALSKQRLVIAGTGPEEQALR
                     GLAAELGADVSFAGYLSGERLHRLIGESRALVLPSEWYENAPISVLETYALERPVIGA
                     AIGGIPEMVKEGETGLLAAPGNVEDLARALREMAALSPAARARMGTAGRSWVATEFSA
                     AAYRERTLDLYAGIGVA"
     misc_feature    854557..855768
                     /locus_tag="Smed_4356"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    854560..855759
                     /locus_tag="Smed_4356"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases and named after YqgM in
                     Bacillus licheniformis about which little is known.
                     Glycosyltransferases catalyze the transfer of sugar
                     moieties from activated donor molecules to...; Region:
                     GT1_YqgM_like; cd03801"
                     /db_xref="CDD:99974"
     gene            855905..857107
                     /locus_tag="Smed_4357"
                     /db_xref="GeneID:5318206"
     CDS             855905..857107
                     /locus_tag="Smed_4357"
                     /note="PFAM: glycosyl transferase group 1; Protein of
                     unknown function DUF1972;
                     KEGG: sme:SMb21502 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313095.1"
                     /db_xref="GI:150376499"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR015393"
                     /db_xref="GeneID:5318206"
                     /translation="MSRKSETSGDRRPAQADALTLTGRQAARVAKRRRVMMLGLRGIP
                     NVQGGVEKHVEMLSSRLTGHGWEVEVVGRRRYLPVSGPHLWNGVRVSPLWAPRMMALE
                     AIIHTFLGICFAAMRRPDVLHIHAVGPALLVPLARLMRLNVVVTHHGYDYDRQKWGAF
                     AKKMLRTGERMGMRLAHGRIAISREIAETMGERYRVPVAFVPNGVAVSHCDVETGVLG
                     EFGLTRRRYILLAARLVPEKRQIDLIKAYAKLGNTGFNLVLAGGAEFESAYEDEVRAL
                     ASRVPGVVLTGFQTGDRLAELFANAALFVLPSSHEGMPIALLEAMAHGLPVLASDIVA
                     NRQLDLPAGDYFPLGDIDALASAISEKTATSLDEQEVLAQTERVESAYSWSSVALKTL
                     DVYRAVTK"
     misc_feature    856010..857104
                     /locus_tag="Smed_4357"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    856010..857092
                     /locus_tag="Smed_4357"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. Glycosyltransferases
                     catalyze the transfer of sugar moieties from activated
                     donor molecules to specific acceptor molecules, forming
                     glycosidic bonds. The acceptor molecule can...; Region:
                     GT1_like_6; cd04955"
                     /db_xref="CDD:100001"
     gene            857104..857493
                     /locus_tag="Smed_4358"
                     /db_xref="GeneID:5318207"
     CDS             857104..857493
                     /locus_tag="Smed_4358"
                     /note="KEGG: sme:SMb21501 hypothetical membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313096.1"
                     /db_xref="GI:150376500"
                     /db_xref="InterPro:IPR000276"
                     /db_xref="InterPro:IPR002197"
                     /db_xref="GeneID:5318207"
                     /translation="MNLRRIASLLAWSLLCVIAYSTLSPLDLRPHMGSSVQIERFGAF
                     GLTGLMFAVAYPRRLPSVLAIVLAAAVGLEFMQMLAADRHARLIDLAVKVAGGGCGVA
                     AGWLLVRQWQRSRPEITGINRHAKLRG"
     sig_peptide     857104..857169
                     /locus_tag="Smed_4358"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.994) with cleavage site probability 0.810 at
                     residue 22"
     gene            857527..858525
                     /locus_tag="Smed_4359"
                     /db_xref="GeneID:5318382"
     CDS             857527..858525
                     /locus_tag="Smed_4359"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb21500 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313097.1"
                     /db_xref="GI:150376501"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318382"
                     /translation="MNVSVIIKTLNEEKRIAATIESALAALERTSGEVVIADSGSSDR
                     TIEIASQYPVVIAQIVPPARPSCGIGPQLGFQHSRKDYICLIDGDMLLDETFLEDAIR
                     FLAEHPAIAGVTGRVEEMHISNLEFARRVSRNAPENRTGAVDRMNGGGLYRRSAIESV
                     GYLSDRNLHGYEEFDLGIRLRSAGWGLYRLDRRFVRHFGHTVNSYRLLVRRWKSKYLF
                     GIGELLRASLGKPYFFQLLHELPELKLWGGVYLWWLACLGLILFLPDTLLAMAAVCLS
                     FAGAVLLVSFRKGGLSMGLYTVVAWFFHAAALPIGLLRRRRQPAEPIESRIFGTAT"
     misc_feature    857527..858162
                     /locus_tag="Smed_4359"
                     /note="Glycosyltransferase like family 2; Region:
                     Glyco_tranf_2_3; pfam13641"
                     /db_xref="CDD:222281"
     misc_feature    857533..858237
                     /locus_tag="Smed_4359"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cl11394"
                     /db_xref="CDD:245596"
     misc_feature    order(857548..857550,857554..857556,857632..857634,
                     857803..857805,857809..857811)
                     /locus_tag="Smed_4359"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            858522..860681
                     /locus_tag="Smed_4360"
                     /db_xref="GeneID:5318383"
     CDS             858522..860681
                     /locus_tag="Smed_4360"
                     /note="KEGG: sme:SMb21499 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313098.1"
                     /db_xref="GI:150376502"
                     /db_xref="GeneID:5318383"
                     /translation="MRRCLLVAALLCTWFPDAGASDQWVPVRDVSLELRTGSPLDFSS
                     LLPNAAIVADRRIVAGPGGRLAFAEAPEKPVRMLCASLAWSPASGGFPDHEAADRYAR
                     QLAMHGYNIARLHFVDASLMFGRQRDFDFDPETLDRVHYLLAALKRHGIYWIIDGLSS
                     SRGAYGGYDDRWDAHGDLKLGLHLDRDAIAHWRVLQEKFLSRVNPYTGTATIRDDALA
                     LVILANENGIEFDSVVHERPERPGYDEALSGPFNRWLLSRYGSTEALARVWGVLDAGE
                     RLETASVRLPANRYADEPRMRDLQAFFVETERASTLRMSKVLRDLGYRGLISTYNNWP
                     TVQTALSRRDLDAVTMNTYHDWVGGYSPGSAQTQDSSLAGGANYMRMIAAARWLGKPF
                     IVSEYDHLFWNRYRYEAGLAMPAYAALQGWDVLCRHGHGPIALAYGEPFAHKRAMLPY
                     AIALDPVARAGETLSALLFRRGDVATSALTIPFAVRGEEDLSDDMQAREPENLTDLAL
                     VGRIGLLPVNGFDRETGVSQPREQDAGTILAALRDHAALAAENRTDVASGLYESETGQ
                     ILLDRRIGQLRVSASATEAAAFSSLREPIELGFMRIAQADGNGLVAISAIDAERTLSQ
                     SRRLLLIFATDAQNSNMVFRDSDEKVIEDFGELPVRIRKNYVDLELSRTAGKWSVSPV
                     GLDGTVYPPVDRGSGRVAFRLSNDTPYGPTTYFLVEM"
     sig_peptide     858522..858584
                     /locus_tag="Smed_4360"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.998) with cleavage site probability 0.807 at
                     residue 21"
     gene            complement(860684..863881)
                     /locus_tag="Smed_4361"
                     /db_xref="GeneID:5318384"
     CDS             complement(860684..863881)
                     /locus_tag="Smed_4361"
                     /note="TIGRFAM: transporter, hydrophobe/amphiphile
                     efflux-1 (HAE1) family;
                     PFAM: acriflavin resistance protein;
                     KEGG: sme:SMb21498 putative acriflavin resistence protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrophobe/amphiphile efflux-1 (HAE1) family
                     protein"
                     /protein_id="YP_001313099.1"
                     /db_xref="GI:150376503"
                     /db_xref="InterPro:IPR000731"
                     /db_xref="InterPro:IPR001036"
                     /db_xref="InterPro:IPR004764"
                     /db_xref="GeneID:5318384"
                     /translation="MISEIFIDRPRFAAVISIVLTLAGLIALTRLPVAQFPDIVPPQV
                     SITASYPGAGADVVEATVAQPIESKVVGVDDMLYMKSTSGADGTYSLTVTFAVGTDPD
                     IATVNVQNRVALAEPVLPAEVKQSGVSVQKRSSSLMQVIAIHGENDEFDNLFLSNYAT
                     INVLDTIKRVPGVGDATLFGAQDYSMRIVLDIDRLTNLGLTPTDVINALKAQNVQAAI
                     GRIGAQPMTDDPLFQLNIQTQGRLTDPAQFGDVVLRAGADGSFVRIRDVAHVELGSVS
                     SDSTARINGKPVAMIGTYQAPGANALAATEGVQQALERLSAAFPEGLTYSVSYDTSDF
                     VQASVENVEHTLLEAFALVIIVVFLFLGNWRATLIPLIAVPVALVGTFAVILAMGFSL
                     NTVSLLALVLAIGIVVDDAIVVVENVERVMEENPGMSAAEASRLAMGEITGAIVAITL
                     VLLSVFVPVAFIPGLSGQLFQQFAVAVSVSMVISAINALTLSPALCAILLKPHHGPKR
                     GVLGWISRGIDRTRNGYAHLAGGIARRAILGLVLLAVAIGASGWLFRIVPTGFLPSED
                     QGAFFAEIRLPEGASFNRTDAVVRQVESLLGSIEGVANVTTVTGYSFLDGIAKSSSAF
                     AIVTMKPFAERESETASVNAAIATVMAQGAAIRNAQVFAFNLPPIIGLGTGSGFEYQL
                     LDLQGRSPAELAATAGGLMVAANQNPQLGPTFSTYSASSPQLYLDLDRDRLQALGVSV
                     SDLFATLQGTLGSYYVNDFNLFGRSWKVTMQAAETDRDAVEDISRLHVRNAAGDMVPV
                     ASVARVNYIVGPQSIVRYNNYRSITLNGQPAPGVSSGQALAAMEQISAATLPPGYSFE
                     WTGTALQELEAAGQTTVILALAVFFAYLFLVALYESWTIPIPVLLSVSVGVAGALVAV
                     LLAGLSFDIYAQIGLVVLIALASKNAILIVEFAKFQREKGVPIVDAAVEGARTRFRAV
                     MMTSFAFIVGLVPLVTAEGAGMLSRRAVGTGVAGGMLAASLLGIFIIPALYVVFQWLR
                     ERGHKLAGLSSHAAVEAPRKGELEESIERDRNVAD"
     misc_feature    complement(860795..863881)
                     /locus_tag="Smed_4361"
                     /note="Cation/multidrug efflux pump [Defense mechanisms];
                     Region: AcrB; COG0841"
                     /db_xref="CDD:223911"
     gene            complement(863884..865005)
                     /locus_tag="Smed_4362"
                     /db_xref="GeneID:5318385"
     CDS             complement(863884..865005)
                     /locus_tag="Smed_4362"
                     /note="TIGRFAM: efflux transporter, RND family, MFP
                     subunit;
                     PFAM: secretion protein HlyD family protein;
                     KEGG: sme:SMb21497 putative acriflavin resistance protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RND family efflux transporter MFP subunit"
                     /protein_id="YP_001313100.1"
                     /db_xref="GI:150376504"
                     /db_xref="InterPro:IPR006143"
                     /db_xref="GeneID:5318385"
                     /translation="MRVSRVLAAVLSCGLLAAADFVVGTADAQQPPPAVTVAPAAVMD
                     LRESVDLTGTVVAIQKVDMRARVSGFIEKVNFEDGQKVSAGTALYQVEDGAYRAALQE
                     IEGSIAAAEAQRDLAILERDRAQRLIATNTVAQATLDTANAQLKKAEADILRLKGSKQ
                     TAELNLSYTKILAPFDGVVGLTAVDVGALVTPESGTLVTLTRLDPIHAEFPVATSLYF
                     SYRERVEKGEISGGANVSIVLPNGTEYPQKGTIDFVASTVSQGTDTVTVRAQFPNPGG
                     VLLDGTLVRVVLEQSDRQDVLAVPQQAVQRDQQGAFVMVVDANSKVELRRVEVSRSSR
                     GQAVVAKGLKEGENVITEGVGKVRPGITVDAVTATTTGG"
     sig_peptide     complement(864919..865005)
                     /locus_tag="Smed_4362"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.853 at
                     residue 29"
     misc_feature    complement(863926..864876)
                     /locus_tag="Smed_4362"
                     /note="RND family efflux transporter, MFP subunit; Region:
                     RND_mfp; TIGR01730"
                     /db_xref="CDD:233547"
     misc_feature    complement(864682..864831)
                     /locus_tag="Smed_4362"
                     /note="Biotin-lipoyl like; Region: Biotin_lipoyl_2;
                     pfam13533"
                     /db_xref="CDD:205711"
     misc_feature    complement(864163..864498)
                     /locus_tag="Smed_4362"
                     /note="HlyD family secretion protein; Region: HlyD_3;
                     pfam13437"
                     /db_xref="CDD:222128"
     gene            complement(865270..865602)
                     /locus_tag="Smed_4363"
                     /db_xref="GeneID:5318386"
     CDS             complement(865270..865602)
                     /locus_tag="Smed_4363"
                     /note="KEGG: sme:SMa0034 possible protease"
                     /codon_start=1
                     /transl_table=11
                     /product="putative protease"
                     /protein_id="YP_001313101.1"
                     /db_xref="GI:150376505"
                     /db_xref="GeneID:5318386"
                     /translation="MNGGSGADSFVFKALSDSTVSRSGRDTIYDYTAQSDRFDLSVID
                     ADISAVGNKAFHFVGTAAFGGKNGELRYIREASDTYIYGDVNGDRKADFAIHLDDAVS
                     LQKGYFVL"
     misc_feature    complement(865312..>865596)
                     /locus_tag="Smed_4363"
                     /note="Peptidase M10 serralysin C terminal; Region:
                     Peptidase_M10_C; pfam08548"
                     /db_xref="CDD:117125"
     gene            complement(865747..866796)
                     /locus_tag="Smed_4364"
                     /pseudo
                     /db_xref="GeneID:5318387"
     gene            866921..867382
                     /locus_tag="Smed_4365"
                     /db_xref="GeneID:5318388"
     CDS             866921..867382
                     /locus_tag="Smed_4365"
                     /note="PFAM: regulatory protein AsnC/Lrp family;
                     KEGG: sme:SMb21493 putative transcriptional regulator,
                     AsnC family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="AsnC family transcriptional regulator"
                     /protein_id="YP_001313102.1"
                     /db_xref="GI:150376506"
                     /db_xref="InterPro:IPR000485"
                     /db_xref="GeneID:5318388"
                     /translation="MSRRAVRDSAVAKYTPDDLDRQIIAHLRSDGRASLSKLSDALGV
                     ARGTVQNRLERLLETGTLLGFTVRVREDYDVSTVHAVMMIEVVGKSTTQVIRRLRGLP
                     EIYTLHTTNGNWDLVANIRAANLSEFDRILREVRMIDGVANSETSLLLSSV"
     misc_feature    866969..867379
                     /locus_tag="Smed_4365"
                     /note="Transcriptional regulators [Transcription]; Region:
                     Lrp; COG1522"
                     /db_xref="CDD:224439"
     misc_feature    866969..867070
                     /locus_tag="Smed_4365"
                     /note="AsnC-type helix-turn-helix domain; Region:
                     HTH_AsnC-type; pfam13404"
                     /db_xref="CDD:205582"
     misc_feature    867182..867376
                     /locus_tag="Smed_4365"
                     /note="AsnC family; Region: AsnC_trans_reg; pfam01037"
                     /db_xref="CDD:216258"
     gene            867490..868068
                     /locus_tag="Smed_4366"
                     /db_xref="GeneID:5318389"
     CDS             867490..868068
                     /locus_tag="Smed_4366"
                     /note="PFAM: protein of unknown function DUF922;
                     KEGG: sme:SMb21492 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313103.1"
                     /db_xref="GI:150376507"
                     /db_xref="InterPro:IPR010321"
                     /db_xref="GeneID:5318389"
                     /translation="MFSVGLPNRHAGDSTGGVAGSREDRDYSITGQSGPELYAAIGER
                     GPRVGGLGRAIAHTSFKLTWRRKYEERDGACVLASALPKLTITYTLPKLSGKLSGNTE
                     ANWETFIDGVKRHERVHGDFIKEMVSAIEVATVGLTVADDPKCRKIKSEMTKRLGELS
                     RAQRQKSRDFDKAELSDGGNIHQLILNLVNGG"
     misc_feature    867568..868065
                     /locus_tag="Smed_4366"
                     /note="Predicted secreted Zn-dependent protease
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: COG5664"
                     /db_xref="CDD:227951"
     gene            868304..868834
                     /locus_tag="Smed_4367"
                     /db_xref="GeneID:5318390"
     CDS             868304..868834
                     /locus_tag="Smed_4367"
                     /note="PFAM: protein of unknown function DUF992;
                     KEGG: sme:SMb21491 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313104.1"
                     /db_xref="GI:150376508"
                     /db_xref="InterPro:IPR009333"
                     /db_xref="GeneID:5318390"
                     /translation="MKKTLAMAFSAVTIAFTAAGANAADLTYQEPAPPPAVQDARGGV
                     KIGYLECDIGGGAGYVLGSSKEVECFFRSLGGDVIEDRYTGEIRKLGVDVGFTMRSRL
                     IWAVFAPTAGYHHGSLSGIYKGATAEATLGAGVGANVLVGGTSGSVHLQTVSVTGQLG
                     LNVAAAGTSMTLNSAN"
     sig_peptide     868304..868375
                     /locus_tag="Smed_4367"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.996 at
                     residue 24"
     misc_feature    868397..868819
                     /locus_tag="Smed_4367"
                     /note="Protein of unknown function (DUF992); Region:
                     DUF992; pfam06186"
                     /db_xref="CDD:218930"
     gene            complement(868854..869609)
                     /locus_tag="Smed_4368"
                     /db_xref="GeneID:5318391"
     CDS             complement(868854..869609)
                     /locus_tag="Smed_4368"
                     /note="PFAM: Surfeit locus 1 family protein;
                     KEGG: rle:pRL110038 putative surfeit locus protein 1"
                     /codon_start=1
                     /transl_table=11
                     /product="Surfeit locus 1 family protein"
                     /protein_id="YP_001313105.1"
                     /db_xref="GI:150376509"
                     /db_xref="InterPro:IPR002994"
                     /db_xref="GeneID:5318391"
                     /translation="MTDLQNETAFRPRSRLAVVSILGLLLIAGLLALGTWQVKRLFWK
                     LDLIARVEQRIGAPPVPAPPRSDWPNVSPARDEYRHVALHGRFLNDEETLVYAATELG
                     AGYWVMTPLALHDGTIVLVNRGFVPMERRDPKARQQGRIEDEVKVTGLMRMDEPKGSL
                     LQSNRPREDRWYSRDVGAIAAARGLSPVAPYFVDADASSIPGTLPVGGLTRVVFPNNH
                     LVYALTWYCLAAMTAGMLVIFWRSARKSNSGAA"
     sig_peptide     complement(869505..869609)
                     /locus_tag="Smed_4368"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.888) with cleavage site probability 0.669 at
                     residue 35"
     misc_feature    complement(868905..869507)
                     /locus_tag="Smed_4368"
                     /note="SURF1 superfamily. Surf1/Shy1 has been implicated
                     in the posttranslational steps of the biogenesis of the
                     mitochondrially-encoded Cox1 subunit of cytochrome c
                     oxidase (complex IV). Cytochrome c oxidase (complex IV),
                     the terminal electron-transferring...; Region: SURF1;
                     cd06662"
                     /db_xref="CDD:119401"
     gene            complement(869711..870112)
                     /locus_tag="Smed_4369"
                     /db_xref="GeneID:5318392"
     CDS             complement(869711..870112)
                     /locus_tag="Smed_4369"
                     /note="TIGRFAM: Cytochrome o ubiquinol oxidase subunit IV;
                     PFAM: cytochrome C oxidase subunit IV;
                     KEGG: rle:pRL110039 putative cytochrome o ubiquinol
                     oxidase protein CyoD"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="YP_001313106.1"
                     /db_xref="GI:150376510"
                     /db_xref="InterPro:IPR005171"
                     /db_xref="InterPro:IPR014210"
                     /db_xref="GeneID:5318392"
                     /translation="MSTHASSHEDAFEAHHGHSHGHGAGHGTLKSYVTGFILSVLLTA
                     IPFWLVMADVLESAILTAAIIMALGAIQIVVHMIFFLHMNTRSEGGWTMMALIFTIVL
                     VAIALSGSLWVMHHLNTNMMPMSPEMMKNMP"
     misc_feature    complement(869762..870031)
                     /locus_tag="Smed_4369"
                     /note="Heme/copper-type cytochrome/quinol oxidase, subunit
                     4 [Energy production and conversion]; Region: CyoD;
                     COG3125"
                     /db_xref="CDD:225667"
     gene            complement(870109..870741)
                     /locus_tag="Smed_4370"
                     /db_xref="GeneID:5317979"
     CDS             complement(870109..870741)
                     /locus_tag="Smed_4370"
                     /note="TIGRFAM: Cytochrome o ubiquinol oxidase subunit
                     III;
                     PFAM: cytochrome c oxidase subunit III;
                     KEGG: sme:SMb21489 putative cytochrome o ubiquinol oxidase
                     chain III protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="YP_001313107.1"
                     /db_xref="GI:150376511"
                     /db_xref="InterPro:IPR000298"
                     /db_xref="InterPro:IPR014206"
                     /db_xref="GeneID:5317979"
                     /translation="MNEFHSSDALHEGKAPAFYLKEEHHPEGSTMLGFWLYLMSDCLI
                     FAVLFATHAVLGRNYAAGPSPADLFDLPLIALNTSMLLFSSITYGFAMLEMEKGRLRA
                     TLAWMAVTALFGIVFVGLELYEFAHLIHEGAGPQRSAFLSSFFTLVGTHGLHVSSGII
                     WMFVLMAQVAKHGLIAENKRRLMCLSMFWHFLDVVWIGVFSFVYLMGVLR"
     misc_feature    complement(870121..870678)
                     /locus_tag="Smed_4370"
                     /note="Ubiquinol oxidase subunit III subfamily. Ubiquinol
                     oxidase, the terminal oxidase in the respiratory chains of
                     aerobic bacteria, is a multi-chain transmembrane protein
                     located in the cell membrane.  It catalyzes the reduction
                     of O2 and simultaneously...; Region:
                     Ubiquinol_oxidase_III; cd02863"
                     /db_xref="CDD:239214"
     misc_feature    complement(order(870589..870591,870598..870603,
                     870610..870615,870634..870636,870643..870645,
                     870655..870660))
                     /locus_tag="Smed_4370"
                     /note="Subunit I/III interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239214"
     misc_feature    complement(order(870172..870174,870193..870195,
                     870478..870483,870493..870495,870502..870504,
                     870613..870615,870637..870639))
                     /locus_tag="Smed_4370"
                     /note="Subunit III/IV interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239214"
     gene            complement(870738..872747)
                     /locus_tag="Smed_4371"
                     /db_xref="GeneID:5317980"
     CDS             complement(870738..872747)
                     /locus_tag="Smed_4371"
                     /EC_number="1.9.3.1"
                     /note="TIGRFAM: Cytochrome o ubiquinol oxidase subunit I;
                     PFAM: cytochrome c oxidase subunit I;
                     KEGG: sme:SMb21488 putative cytochrome o ubiquinol oxidase
                     chain I protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="YP_001313108.1"
                     /db_xref="GI:150376512"
                     /db_xref="InterPro:IPR000883"
                     /db_xref="InterPro:IPR014207"
                     /db_xref="GeneID:5317980"
                     /translation="MFSDPDLLKLIFGRLTLDAIPYHEPILVATFAAVVLGGIALTGL
                     ITYYRFWGTLWHDWLTSVDHKKIGIMYIILALVMLLRGFSDAIMMRLQQAMAFGGSEG
                     YLPPHHYDQIFTAHGVIMIFFMAMPFVTGLMNFVVPLQIGARDVSFPFLNNFSFWMTA
                     AGAAIIMLSLFVGEFARTGWLAYPPLSGADYSPGVGVDYYIWGLQIAGIGTTLSGINL
                     IATIVKMRAPGMTMMKMPVFTWTSLCTNVLIVATFPVLTATLALLTLDRYAGTNFFTN
                     DLGGNPMMYVNLIWIWGHPEVYILILPAFGIFSEVVATFCGKRLFGYASMVYATVVIT
                     ILSYIVWLHHFFTMGSGASVNAFFGITTMIISIPTGAKMFNWLFTMYRGRIRYEVPML
                     WTIGFMVTFVLGGMTGVLLAVPPADFVLHNSLFLIAHFHNVIIGGVVFGLMAGVVYWF
                     PKAFGFRLDPFWGKMSFWFWLIGFYFAFIPLYVLGLMGVTRRVSQFEDPSLQIWFVIA
                     AFGAFLIALGILSMLIQLVVSFMNREKLRDMTGDPWDGRTLEWSIASPPPDYNFAFTP
                     LVHDQDSWWDMKKRGYERPLTGFKPIHMPKNTGTGVILGAISVVFAFAMVWYMWWLAI
                     LSFVAMVVIAIGHTFNYDRDFYIPANVVADTEGKRAEELAAEVQA"
     misc_feature    complement(870897..872588)
                     /locus_tag="Smed_4371"
                     /note="Heme/copper-type cytochrome/quinol oxidases,
                     subunit 1 [Energy production and conversion]; Region:
                     CyoB; COG0843"
                     /db_xref="CDD:223913"
     misc_feature    complement(871062..872576)
                     /locus_tag="Smed_4371"
                     /note="Ubiquinol oxidase subunit I.  Ubiquinol oxidase,
                     the terminal oxidase in the respiratory chains of aerobic
                     bacteria, is a multi-chain transmembrane protein located
                     in the cell membrane.  It catalyzes the reduction of O2
                     and simultaneously pumps protons...; Region:
                     Ubiquinol_Oxidase_I; cd01662"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(872085..872087,872097..872099,
                     872115..872120,872283..872285,872292..872294,
                     872313..872315,872343..872345,872535..872537))
                     /locus_tag="Smed_4371"
                     /note="D-pathway; other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(872409..872417,872424..872426,
                     872481..872486,872493..872495,872505..872507))
                     /locus_tag="Smed_4371"
                     /note="Putative ubiquinol binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(871203..871205,871317..871319,
                     871443..871445,871455..871457,872400..872402))
                     /locus_tag="Smed_4371"
                     /note="Low-spin heme (heme b) binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(871275..871277,871482..871487,
                     871497..871499,871887..871892,871905..871907))
                     /locus_tag="Smed_4371"
                     /note="Putative water exit pathway; other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(871461..871463,871716..871721,
                     871866..871868))
                     /locus_tag="Smed_4371"
                     /note="Binuclear center (heme o3/CuB) [ion binding]; other
                     site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(871632..871634,871641..871643,
                     871716..871721,871821..871823,871854..871856,
                     871866..871868))
                     /locus_tag="Smed_4371"
                     /note="K-pathway; other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(871272..871277,871482..871487,
                     871716..871718))
                     /locus_tag="Smed_4371"
                     /note="Putative proton exit pathway; other site"
                     /db_xref="CDD:238832"
     gene            complement(872900..874078)
                     /locus_tag="Smed_4372"
                     /db_xref="GeneID:5317981"
     CDS             complement(872900..874078)
                     /locus_tag="Smed_4372"
                     /note="TIGRFAM: ubiquinol oxidase, subunit II;
                     PFAM: cytochrome c oxidase subunit II; COX aromatic rich
                     domain protein;
                     KEGG: sme:SMb21487 putative cytochrome o ubiquinol oxidase
                     chain II protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol oxidase subunit II"
                     /protein_id="YP_001313109.1"
                     /db_xref="GI:150376513"
                     /db_xref="InterPro:IPR002429"
                     /db_xref="InterPro:IPR006333"
                     /db_xref="InterPro:IPR010514"
                     /db_xref="InterPro:IPR011759"
                     /db_xref="GeneID:5317981"
                     /translation="MPEPLKFSRRLAVLPLFLLMAGCDMVVMSPSGDIAAQQRDLIVI
                     STILMLLIIVPVVFLTLFFAWRYRRSNTSATYDPEWHHSTALEVVIWSAPLAIIIALG
                     AITWISTHKLDPYRPLDRLDAERAIPADAKPLTVEVVALDWKWLFFYPELGVATVNEL
                     AAPVDVPIHFKITASSVMNSFYIPALAGQIYAMPGMETKLHAVINKQGEYEGFSANYS
                     GDGFSHMRFKFHGLDRQGFEEWVSRVKTQGTALNRDTYLKLEKPSQREPVRYFARVED
                     GLYTAILNLCVTPGKMCMQQMMHIDMMGGAGKESAGNREKLEYDNRHSLAEGAPAATH
                     PATGTPARSQQEPQGTGGGEQPMQHPMPGMGAHQGHSMPGMNHESDHENDPAPAQLNH
                     "
     sig_peptide     complement(873971..874078)
                     /locus_tag="Smed_4372"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.677) with cleavage site probability 0.307 at
                     residue 36"
     misc_feature    complement(873344..874048)
                     /locus_tag="Smed_4372"
                     /note="cytochrome o ubiquinol oxidase subunit II; Region:
                     CyoA; TIGR01433"
                     /db_xref="CDD:213620"
     misc_feature    complement(873404..873679)
                     /locus_tag="Smed_4372"
                     /note="Cytochrome C oxidase subunit II, periplasmic
                     domain; Region: COX2; pfam00116"
                     /db_xref="CDD:201014"
     misc_feature    complement(873206..873346)
                     /locus_tag="Smed_4372"
                     /note="COX Aromatic Rich Motif; Region: COX_ARM;
                     pfam06481"
                     /db_xref="CDD:203465"
     gene            874380..875720
                     /locus_tag="Smed_4373"
                     /db_xref="GeneID:5317982"
     CDS             874380..875720
                     /locus_tag="Smed_4373"
                     /note="PFAM: General substrate transporter;
                     KEGG: sme:SMb21486 putative metabolite transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="general substrate transporter"
                     /protein_id="YP_001313110.1"
                     /db_xref="GI:150376514"
                     /db_xref="InterPro:IPR005828"
                     /db_xref="InterPro:IPR005829"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="GeneID:5317982"
                     /translation="MNGAIQQSLGPSSSSMERDARRIHDDRPVSAGNIAIGVVIGRAA
                     EFFDFFVFGIASVVVFPQLFFPFAPDRLTATLYSFAIFALAFMARPVGSLVFMAIDRT
                     YGRGVKLTIALFLLGGSTASIAFLPGYATLGGWSILLLAVFRLGQGFALGGAWDGLAS
                     LLALNAPQHHRGWYAMIPQLGAPLGFMLASALFAYFLASLSQADFLAWGWRYPFFVAF
                     AINVVALFTRLRLVMTKEFGTLLDLHELQASRVTEVLRVNGGHVLVGAFVPLASFALF
                     HLVTVFPLSWVEIYTDHGASSFLMVQFLGAVCGIVAIVASGLIADRIGRRNHLGMCAV
                     LIAIFSFVAPMLLQSGATGREMFVIVGFTILGLSFGQAAGAVASRFGRAYRYTGAALT
                     SDLSWLIGAGFAPLVALGLTSRFGLAFAGYYLLSGALCTILALIFSKTLEINNE"
     misc_feature    874500..875672
                     /locus_tag="Smed_4373"
                     /note="metabolite-proton symporter; Region: 2A0106;
                     TIGR00883"
                     /db_xref="CDD:233168"
     misc_feature    874620..875690
                     /locus_tag="Smed_4373"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    order(874623..874625,874632..874637,874644..874646,
                     874656..874661,874665..874670,874830..874835,
                     874842..874847,874854..874859,874866..874868,
                     874902..874907,874914..874919,874935..874937,
                     875169..875171,875178..875183,875190..875195,
                     875202..875204,875244..875246,875283..875285,
                     875295..875297,875304..875306,875316..875318,
                     875460..875462,875472..875477,875484..875486,
                     875496..875501,875508..875510,875541..875546,
                     875553..875558,875568..875573,875580..875582)
                     /locus_tag="Smed_4373"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            875900..876088
                     /locus_tag="Smed_4374"
                     /db_xref="GeneID:5317983"
     CDS             875900..876088
                     /locus_tag="Smed_4374"
                     /note="KEGG: rsp:RSP_0947 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313111.1"
                     /db_xref="GI:150376515"
                     /db_xref="GeneID:5317983"
                     /translation="MPAKSKAQQMAAGAALAAKRGEKKKSELKGASRSMEDSMTEKEL
                     EEMASTKRKGKKEHVSKK"
     misc_feature    <875975..876079
                     /locus_tag="Smed_4374"
                     /note="Protein of unknwon function (DUF3008); Region:
                     DUF3008; pfam11450"
                     /db_xref="CDD:204650"
     gene            complement(876217..876477)
                     /locus_tag="Smed_4375"
                     /db_xref="GeneID:5317984"
     CDS             complement(876217..876477)
                     /locus_tag="Smed_4375"
                     /note="KEGG: sme:SMb21687 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313112.1"
                     /db_xref="GI:150376516"
                     /db_xref="GeneID:5317984"
                     /translation="MQFPGQFEKTLWHRFLAHLLDERCNPLVNGFFRVLIRGNLAIVH
                     SPVLSHDPDLATEYCSCFALYIIKTAGVKGLQPSQPETFFRP"
     gene            complement(876529..877050)
                     /locus_tag="Smed_4376"
                     /db_xref="GeneID:5317985"
     CDS             complement(876529..877050)
                     /locus_tag="Smed_4376"
                     /note="TIGRFAM: RNA polymerase sigma-70;
                     PFAM: sigma-70 region 2 domain protein; sigma-70 region 4
                     domain protein; Sigma-70 region 4 type 2;
                     KEGG: sme:SMb21484 putative RNA polymerase sigma-E factor
                     (sigma-24) protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF subfamily RNA polymerase sigma-24 factor"
                     /protein_id="YP_001313113.1"
                     /db_xref="GI:150376517"
                     /db_xref="InterPro:IPR000838"
                     /db_xref="InterPro:IPR007627"
                     /db_xref="InterPro:IPR007630"
                     /db_xref="InterPro:IPR013249"
                     /db_xref="InterPro:IPR014284"
                     /db_xref="GeneID:5317985"
                     /translation="MPAIGGHASQQSPLLEEQVVDLIPALRAFARTFTTASFEADDLV
                     QETLLRALRSIEQFQPGTSLKSWLFTIMRNAFRTQYKIRTRESPGSTNCAELPIPTAP
                     SQEWSVLNGELRNALGALSPEHREVLVLVAGFGLSYKEAADICDCAIGTIKSRLSRAR
                     DELTAQMHGNPLN"
     misc_feature    complement(876562..877026)
                     /locus_tag="Smed_4376"
                     /note="RNA polymerase sigma factor; Provisional; Region:
                     PRK12547"
                     /db_xref="CDD:139056"
     misc_feature    complement(876793..>876936)
                     /locus_tag="Smed_4376"
                     /note="Sigma-70 region 2; Region: Sigma70_r2; pfam04542"
                     /db_xref="CDD:218138"
     misc_feature    complement(876562..876717)
                     /locus_tag="Smed_4376"
                     /note="Sigma70, region (SR) 4 refers to the most
                     C-terminal of four conserved domains found in Escherichia
                     coli (Ec) sigma70, the main housekeeping sigma, and
                     related sigma-factors (SFs). A SF is a dissociable subunit
                     of RNA polymerase, it directs bacterial or...; Region:
                     Sigma70_r4; cd06171"
                     /db_xref="CDD:100119"
     misc_feature    complement(order(876571..876573,876577..876582,
                     876586..876594,876598..876603,876607..876609,
                     876637..876642,876658..876660,876688..876690))
                     /locus_tag="Smed_4376"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:100119"
     gene            877294..877578
                     /locus_tag="Smed_4377"
                     /db_xref="GeneID:5317986"
     CDS             877294..877578
                     /locus_tag="Smed_4377"
                     /note="PFAM: protein of unknown function DUF1236;
                     KEGG: sme:SMb21483 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313114.1"
                     /db_xref="GI:150376518"
                     /db_xref="InterPro:IPR009642"
                     /db_xref="GeneID:5317986"
                     /translation="MNRFATLTAALFLGFGSAAIAQTTVVLPGEVRTYVLEQNTPSVT
                     YEGEIVVGQPIPETVEIHTIPEQPDFAYAVVNDRRVVVNPKTHTVVEVLE"
     sig_peptide     877294..877359
                     /locus_tag="Smed_4377"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.992 at
                     residue 22"
     misc_feature    877393..877575
                     /locus_tag="Smed_4377"
                     /note="Protein of unknown function (DUF1236); Region:
                     DUF1236; pfam06823"
                     /db_xref="CDD:219192"
     gene            877703..877966
                     /locus_tag="Smed_4378"
                     /db_xref="GeneID:5317987"
     CDS             877703..877966
                     /locus_tag="Smed_4378"
                     /note="KEGG: sme:SMb21482 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313115.1"
                     /db_xref="GI:150376519"
                     /db_xref="GeneID:5317987"
                     /translation="MENNSSEFRLAAQREILVAVLSALYRHKDLWREIKRALEEVPIV
                     QDHEEDPGIVPSEAFARQNAMTSEIASILDDAQARSDLGPETR"
     gene            878268..878744
                     /locus_tag="Smed_4379"
                     /db_xref="GeneID:5317988"
     CDS             878268..878744
                     /locus_tag="Smed_4379"
                     /note="PFAM: CBS domain containing protein;
                     KEGG: sme:SMb21481 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="signal-transduction protein"
                     /protein_id="YP_001313116.1"
                     /db_xref="GI:150376520"
                     /db_xref="InterPro:IPR000644"
                     /db_xref="GeneID:5317988"
                     /translation="MAGHDDRMVRVRDVMSRQVFTVSPTDSAQSVARLMAETGVGAVP
                     VETPGVGTILGIVTDRDIVTSVVAKGLSSSTAVFEFMTVSAESCEEHDSLLLAAQKMH
                     DLRIRRLVVVNEKRQAAGIVALADISRVNPELGGLVLEGINRPVPVESRLEGMSTC"
     misc_feature    878316..878654
                     /locus_tag="Smed_4379"
                     /note="The CBS domain, named after human CBS, is a small
                     domain originally identified in cystathionine
                     beta-synthase and is subsequently found in a wide range of
                     different proteins. CBS domains usually occur in tandem
                     repeats. They associate to form a so-called...; Region:
                     CBS_pair_9; cd04622"
                     /db_xref="CDD:239994"
     misc_feature    878316..878648
                     /locus_tag="Smed_4379"
                     /note="FOG: CBS domain [General function prediction only];
                     Region: COG0517"
                     /db_xref="CDD:223591"
     gene            878738..878998
                     /locus_tag="Smed_4380"
                     /db_xref="GeneID:5317989"
     CDS             878738..878998
                     /locus_tag="Smed_4380"
                     /note="PFAM: protein of unknown function DUF982;
                     KEGG: sme:SMb21480 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313117.1"
                     /db_xref="GI:150376521"
                     /db_xref="InterPro:IPR010385"
                     /db_xref="GeneID:5317989"
                     /translation="MLTQDRLWSEAVILEGGKNRVLRVQSTRDAFLCLKNHWPIADGD
                     AKRDAFAACERVIEGNDEPDIARSAFIKAAEEAKFSVHSWTG"
     misc_feature    878771..878980
                     /locus_tag="Smed_4380"
                     /note="Protein of unknown function (DUF982); Region:
                     DUF982; pfam06169"
                     /db_xref="CDD:218923"
     gene            complement(879047..879352)
                     /locus_tag="Smed_4381"
                     /db_xref="GeneID:5318351"
     CDS             complement(879047..879352)
                     /locus_tag="Smed_4381"
                     /note="KEGG: sme:SMb21479 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313118.1"
                     /db_xref="GI:150376522"
                     /db_xref="GeneID:5318351"
                     /translation="MAAEFGEGTMVQGGEVIAFPLAARAGDVARCARELDRIHGAAAV
                     HYWKGECRRLAEQLAILGVDEAGVREEVLAFQAEVQAAMAERYNEPASRNRSGPRQR"
     gene            complement(879687..880469)
                     /gene="fabG"
                     /locus_tag="Smed_4382"
                     /db_xref="GeneID:5318352"
     CDS             complement(879687..880469)
                     /gene="fabG"
                     /locus_tag="Smed_4382"
                     /EC_number="1.1.1.100"
                     /note="Catalyzes the first of the two reduction steps in
                     the elongation cycle of fatty acid synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="YP_001313119.1"
                     /db_xref="GI:150376523"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5318352"
                     /translation="MNRTSTVALVTGAGSGIGRATALALALDGVKIGALGRTGSEVET
                     VAGEIAKAGGEAMALEADISDELQMRNAVNGLVGKFGHLDIVVANAGINGVWAPIDDL
                     KPFEWDETIAVNLRGTFLTLHLTVPHLKQRGGGSIVVVSSINGTRTFTTPGATAYTAT
                     KAAQVAMVQQLALELGKHHIRVNAVCPGEIETNIDDNTKLRHEEETAIPVEWPDGQVP
                     ISDGQPGRSEDVAEVIRFLVSDRARHVTGSPVWIDGGQGLLR"
     misc_feature    complement(879696..880469)
                     /gene="fabG"
                     /locus_tag="Smed_4382"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Validated; Region: fabG; PRK05653"
                     /db_xref="CDD:235546"
     sig_peptide     complement(880395..880469)
                     /gene="fabG"
                     /locus_tag="Smed_4382"
                     /product="3-ketoacyl-(acyl-carrier-protein) reductase"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.995) with cleavage site probability 0.582 at
                     residue 25"
     misc_feature    complement(879711..880448)
                     /gene="fabG"
                     /locus_tag="Smed_4382"
                     /note="classical (c) SDRs; Region: SDR_c; cd05233"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(879891..879896,879900..879911,
                     879987..879989,879999..880001,880044..880052,
                     880131..880133,880197..880205,880281..880289,
                     880356..880364,880419..880430,880434..880436))
                     /gene="fabG"
                     /locus_tag="Smed_4382"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:212491"
     misc_feature    complement(order(879987..879989,879999..880001,
                     880044..880046,880128..880130))
                     /gene="fabG"
                     /locus_tag="Smed_4382"
                     /note="active site"
                     /db_xref="CDD:212491"
     gene            complement(880466..880837)
                     /locus_tag="Smed_4383"
                     /db_xref="GeneID:5318353"
     CDS             complement(880466..880837)
                     /locus_tag="Smed_4383"
                     /note="KEGG: sme:SMb21473 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313120.1"
                     /db_xref="GI:150376524"
                     /db_xref="GeneID:5318353"
                     /translation="MHLVGTQVIPEQGGKAGFTVEFVGEGGEIVSVSMRNDAATNINR
                     LNAIERAQAVMRELADADCDAIEESQNSPEFHRSARGAKDTDEMERQLDEGLEDTFPA
                     SDPVSVTVSTIPTDRAKNGKP"
     gene            complement(880905..881360)
                     /locus_tag="Smed_4384"
                     /db_xref="GeneID:5318354"
     CDS             complement(880905..881360)
                     /locus_tag="Smed_4384"
                     /note="PFAM: protein of unknown function DUF1452;
                     KEGG: sme:SMb21472 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313121.1"
                     /db_xref="GI:150376525"
                     /db_xref="InterPro:IPR010842"
                     /db_xref="GeneID:5318354"
                     /translation="MPKANGFSRFASAVAEYAGRPAVFVLALALIGAWAVTGPIFGFS
                     QTWQLVVNTGTTIVTFLMVFVLQNTQNRDGRALQAKLDELILTSSAENRYVGIEKLDE
                     KELKRLAEILRKHAHDQDDDELREKVSSAAERRGLGRANRNQNTRQPFA"
     misc_feature    complement(880953..881342)
                     /locus_tag="Smed_4384"
                     /note="Low affinity iron permease; Region: Iron_permease;
                     pfam04120"
                     /db_xref="CDD:202897"
     gene            complement(881461..881709)
                     /locus_tag="Smed_4385"
                     /db_xref="GeneID:5318355"
     CDS             complement(881461..881709)
                     /locus_tag="Smed_4385"
                     /note="PFAM: protein of unknown function DUF982;
                     KEGG: sme:SMb21471 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313122.1"
                     /db_xref="GI:150376526"
                     /db_xref="InterPro:IPR010385"
                     /db_xref="GeneID:5318355"
                     /translation="MDPGPWNECVPVRMPDNSKIHMVSNTRQAFELLTQHWPTSHGQA
                     YLAAIDICRAVLDRDSPAYVARAAFVAAAKEAQVNVVT"
     misc_feature    complement(<881527..881691)
                     /locus_tag="Smed_4385"
                     /note="Protein of unknown function (DUF982); Region:
                     DUF982; pfam06169"
                     /db_xref="CDD:218923"
     gene            complement(881687..881968)
                     /locus_tag="Smed_4386"
                     /db_xref="GeneID:5318356"
     CDS             complement(881687..881968)
                     /locus_tag="Smed_4386"
                     /note="PFAM: protein of unknown function DUF982;
                     KEGG: sme:SMb21470 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313123.1"
                     /db_xref="GI:150376527"
                     /db_xref="InterPro:IPR010385"
                     /db_xref="GeneID:5318356"
                     /translation="MYEIPWSRPVKITMLDGRCRTVVGPLDAMHCLQSEWPVRDGAYY
                     GCAIRACNAALKRRKRPEDARAAFIAALREAFLTVAPLQEGGHGPRPLE"
     misc_feature    complement(<881780..881947)
                     /locus_tag="Smed_4386"
                     /note="Protein of unknown function (DUF982); Region:
                     DUF982; pfam06169"
                     /db_xref="CDD:218923"
     gene            complement(882020..882529)
                     /locus_tag="Smed_4387"
                     /db_xref="GeneID:5318357"
     CDS             complement(882020..882529)
                     /locus_tag="Smed_4387"
                     /note="PFAM: protein of unknown function DUF982;
                     KEGG: sme:SMb21469 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313124.1"
                     /db_xref="GI:150376528"
                     /db_xref="InterPro:IPR010385"
                     /db_xref="GeneID:5318357"
                     /translation="MRSVFMVAIPAGVTCWRYRHRESAVNSRQRGPAPMFIPHSDVQE
                     RDASYLAMPRCASRGQPRACGGTKSLCPKFYFRPATTARLGVMHCFWWDKSVELELGA
                     EGKYRDVKSTREAVECLSQRWPQRDGRALAAAKRVCLQALEGKVGAEKARRAFIKAAE
                     EAHISIRSH"
     misc_feature    complement(882026..882253)
                     /locus_tag="Smed_4387"
                     /note="Protein of unknown function (DUF982); Region:
                     DUF982; pfam06169"
                     /db_xref="CDD:218923"
     gene            882626..883723
                     /locus_tag="Smed_4388"
                     /db_xref="GeneID:5318358"
     CDS             882626..883723
                     /locus_tag="Smed_4388"
                     /note="PFAM: protein of unknown function DUF475;
                     KEGG: sme:SMb21468 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313125.1"
                     /db_xref="GI:150376529"
                     /db_xref="InterPro:IPR007427"
                     /db_xref="GeneID:5318358"
                     /translation="MTGGSTQTSSLGYFKWAFIVTGAGLLLGAWLGWQSTGTLGGMMT
                     VFFICTVLAVLEISLSFDNAIVNANKLKDMTPVWQQRFLTWGILIAVFGMRIVFPLLI
                     VVIAASIGPIEAVILAATQPEEYSRIMHEAHLPIAAFGGTFLMMVGLTYFFDHEKDVH
                     WIAWLESRMARFATIKGVEIAFVLALILGFSKLLEADEAVVFVHACVYGLLTFLAVEV
                     VGGLLDASQQTMSAAAKGGFGAFLYLEVLDASFSFDGVIGAFALTQNLFIIAIGLGIG
                     AMYVRSMTIMLVEKKTLSEYRYLEHGAFYAILILSVVMYFQTLVHIPEVITGLGGAGL
                     IGLSLWSSVRHNRREMEQVEDDTRGRRRVEA"
     misc_feature    882647..883687
                     /locus_tag="Smed_4388"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG2899"
                     /db_xref="CDD:225452"
     gene            883930..884256
                     /locus_tag="Smed_4389"
                     /db_xref="GeneID:5318359"
     CDS             883930..884256
                     /locus_tag="Smed_4389"
                     /note="KEGG: sme:SMb21467 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313126.1"
                     /db_xref="GI:150376530"
                     /db_xref="GeneID:5318359"
                     /translation="MNTSPNDLALIAVMRRYFSLKEEASALKGRLEDARKAAGDEIDP
                     FYDPRRNAPHAEDILVWHRLRREMDELMSLAATWGRGGSIDAFAPAPAAEPAFPPETG
                     ASMEES"
     gene            884516..886264
                     /locus_tag="Smed_4390"
                     /db_xref="GeneID:5318360"
     CDS             884516..886264
                     /locus_tag="Smed_4390"
                     /note="TIGRFAM: type I secretion system ATPase;
                     PFAM: ABC transporter transmembrane region; ABC
                     transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21466 ABC transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="type I secretion system ATPase"
                     /protein_id="YP_001313127.1"
                     /db_xref="GI:150376531"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR010128"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="GeneID:5318360"
                     /translation="MATSNGRNADPASALRDCRTAFIGVAIASALVNVLYLTGSFFML
                     EVYDRILPSRSIPSLVALSLLALLLYAFQGAFELVRGRMLVRIAGALDESLNGRIYRA
                     IVKAPLKLRMQGDGLQALRDFDQVRSFLSGAGPAALFDLPWLPFYIAICFLFHPVIGL
                     VAIIGGLVLMLLTYLTNRGTQAPARKASEAGGLRNAFAQASQRNAEVVHAMGMSARLT
                     AMWERRNTEFRDENRRTSDIGNGYGALSKVFRMALQSCVLAAGAVLVIRGEASPGIII
                     AGSILTARALAPVELAIGNWRGLVAARQSWQRLKELLKALPEADAPLQLPTPRDRLTV
                     EGLASGPPAAQRLILSDVNFTVGAGGAVGVIGPSASGKSSLARAILGIWPAYRGSVRL
                     DGAALDQWDSDELGKHIGYLPQDVELFAGTIAQNICRFAEDATPDAIVAAAKAARVND
                     LILRLPNGYDTEIGDGGMTLSAGQRQRVALARALYGNPFLVVLDEPNSNLDAEGEQAL
                     SEAIMSVRSRGGIVIVVAHRPSALASVDLVLMMNEGRMQAFGPKEQVLGQVLRPQQVE
                     RQNSLKIVAEGQEAKQ"
     misc_feature    884516..886249
                     /locus_tag="Smed_4390"
                     /note="ABC-type protease/lipase transport system, ATPase
                     and permease components [General function prediction
                     only]; Region: ArpD; COG4618"
                     /db_xref="CDD:226969"
     misc_feature    884723..885382
                     /locus_tag="Smed_4390"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:216049"
     misc_feature    885509..886153
                     /locus_tag="Smed_4390"
                     /note="ATP-binding cassette domain of PrtD, subfamily C;
                     Region: ABCC_Protease_Secretion; cd03246"
                     /db_xref="CDD:213213"
     misc_feature    885611..885634
                     /locus_tag="Smed_4390"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213213"
     misc_feature    order(885620..885625,885629..885637,885755..885757,
                     885995..886000,886094..886096)
                     /locus_tag="Smed_4390"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213213"
     misc_feature    885746..885757
                     /locus_tag="Smed_4390"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213213"
     misc_feature    885923..885952
                     /locus_tag="Smed_4390"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213213"
     misc_feature    885983..886000
                     /locus_tag="Smed_4390"
                     /note="Walker B; other site"
                     /db_xref="CDD:213213"
     misc_feature    886007..886018
                     /locus_tag="Smed_4390"
                     /note="D-loop; other site"
                     /db_xref="CDD:213213"
     misc_feature    886082..886102
                     /locus_tag="Smed_4390"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213213"
     gene            886261..887577
                     /locus_tag="Smed_4391"
                     /db_xref="GeneID:5318361"
     CDS             886261..887577
                     /locus_tag="Smed_4391"
                     /note="TIGRFAM: type I secretion membrane fusion protein,
                     HlyD family;
                     PFAM: secretion protein HlyD family protein;
                     KEGG: sme:SMb21465 protein secretion protein, HlyD family"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family type I secretion membrane fusion
                     protein"
                     /protein_id="YP_001313128.1"
                     /db_xref="GI:150376532"
                     /db_xref="InterPro:IPR003997"
                     /db_xref="InterPro:IPR006143"
                     /db_xref="InterPro:IPR010129"
                     /db_xref="GeneID:5318361"
                     /translation="MRGWPQAKPTAHRSLSRHLIGVSVLALALVAGVGGWAATTELSS
                     AIVAGGVVVVDDNVKKVQHLTGGIVGELLVKEGDRVEAGQVLIRLDGTTVRANLAIIE
                     GTLAQFYARRARLLAERIGAASFEIEEDLAEFISGTAAEKLIDGEQRLFANRRSALLG
                     MKGQLDSRKAQLADETEGLTVQLNAIEDALKLIAEELTGVDSLFGQGLVPMQRVTTLK
                     RQRAELEGGRGRHIAARAQARGKSSEIDLQILQLDEDRRTEISKELTDVEAKIAEYEE
                     RRTAAADQLRRLDITAPLSGRIYQLAIHTVNGVINPGETLMLVVPEVDDLTVEAKVAT
                     HDIDQIRVGQSVEIRFSAFNQRTTPEVEAEVVTVAPDLVTDERTGASYYPLRIRPKTE
                     SLAKLKGLSLYPGMPAEVFIKIADRTVISYLTKPLTDQMRHAFRED"
     sig_peptide     886261..886374
                     /locus_tag="Smed_4391"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.995) with cleavage site probability 0.986 at
                     residue 38"
     misc_feature    886444..887328
                     /locus_tag="Smed_4391"
                     /note="HlyD family secretion protein; Region: HlyD;
                     pfam00529"
                     /db_xref="CDD:215974"
     misc_feature    886459..886578
                     /locus_tag="Smed_4391"
                     /note="Biotin-lipoyl like; Region: Biotin_lipoyl_2;
                     pfam13533"
                     /db_xref="CDD:205711"
     misc_feature    887128..>887328
                     /locus_tag="Smed_4391"
                     /note="HlyD family secretion protein; Region: HlyD_3;
                     pfam13437"
                     /db_xref="CDD:222128"
     gene            complement(887594..888367)
                     /locus_tag="Smed_4392"
                     /db_xref="GeneID:5319157"
     CDS             complement(887594..888367)
                     /locus_tag="Smed_4392"
                     /note="PFAM: regulatory protein GntR HTH; UbiC
                     transcription regulator-associated domain protein;
                     KEGG: sme:SMb21464 putative transcriptional regulator,
                     gntR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001313129.1"
                     /db_xref="GI:150376533"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011663"
                     /db_xref="GeneID:5319157"
                     /translation="MARQENLPDERPIDRNHPDALYAQLRNLLRGMIERRELAVNDKL
                     PSERELVAVYGVSRITVRQAIKELENLGYLQTRPGKGIYVTEPAPVYELEVVRSFTQT
                     AHANNRKPGMRLLRAEIARADPEVARPLSLPTGAEVVFLERLRLLDGVPVVVQRDWFS
                     ASLTPGILDIDWTVENRSLYDEFENRYGILPSRGQSTLSARLASDLEASLLQLDRPAA
                     VLTLDQIAYDSHNRTVNISAAAYHPTRYPLSLTQSHRRF"
     misc_feature    complement(887615..888328)
                     /locus_tag="Smed_4392"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PhnF; COG2188"
                     /db_xref="CDD:225099"
     misc_feature    complement(888113..888307)
                     /locus_tag="Smed_4392"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(888122..888133,888137..888142,
                     888170..888172,888179..888184,888188..888202,
                     888224..888229,888233..888235,888302..888304))
                     /locus_tag="Smed_4392"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(887630..888049)
                     /locus_tag="Smed_4392"
                     /note="UTRA domain; Region: UTRA; pfam07702"
                     /db_xref="CDD:219527"
     gene            888570..889955
                     /locus_tag="Smed_4393"
                     /db_xref="GeneID:5319158"
     CDS             888570..889955
                     /locus_tag="Smed_4393"
                     /note="PFAM: glycoside hydrolase family 4;
                     KEGG: sme:SMb21463 putative glycosyl hydrolase, probable
                     6-phospho-beta-glucosidases protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="YP_001313130.1"
                     /db_xref="GI:150376534"
                     /db_xref="InterPro:IPR001088"
                     /db_xref="GeneID:5319158"
                     /translation="MKLTLIGGGGVRAPLFVGSALRRAERSGLTEICLQDINERKLEL
                     FGRISQELARRMQSPVRITMAADAERALEGASYVVTTVRPGDEDGRIKDERIALAHGV
                     LGQETTGPGGFAMALRSIPVILKYAEILKNVSPDAWLFNFTNPAGLVTQALQDEGYHR
                     TVGICDGANGAQEALARWYKVPQNDVHCEVYGLNHLSFTRRATIDGREVLQSLLDDDG
                     FIRSTSQRMFDAGLIRSQRNWINEYLYYYYYAEKAVEALKADARTRGEEVKDLNAALI
                     TRLSAMDMDADAEAALAAYYAYERRRNATYMHYALADAPSMEEADRLVEGLAAGETGE
                     EGEGYAGVALNLVDALQTGKACYSGLNVRNEGAIEGLRDDDVVEVSCVVGQDGIRPMK
                     IGAMPEAQAQLVHSVKRYERLAVRAIRQRSRDLAVQALMAHPLVLSYSRAVPLVDEYL
                     AAHAEFAGEWS"
     misc_feature    888570..889952
                     /locus_tag="Smed_4393"
                     /note="Alpha-galactosidases/6-phospho-beta-glucosidases,
                     family 4 of glycosyl hydrolases [Carbohydrate transport
                     and metabolism]; Region: CelF; COG1486"
                     /db_xref="CDD:224403"
     misc_feature    888570..889940
                     /locus_tag="Smed_4393"
                     /note="Glycoside Hydrolases Family 4;
                     Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase;
                     cd05296"
                     /db_xref="CDD:133432"
     misc_feature    order(888594..888599,888603..888605,888675..888680,
                     888690..888692,888810..888818,888885..888887,
                     888945..888947,888993..888995,888999..889001,
                     889383..889385,889569..889571,889584..889586)
                     /locus_tag="Smed_4393"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:133432"
     misc_feature    order(888837..888839,888885..888887,888999..889001,
                     889065..889067,889152..889154,889296..889298,
                     889359..889361,889569..889574,889584..889586)
                     /locus_tag="Smed_4393"
                     /note="sugar binding site [chemical binding]; other site"
                     /db_xref="CDD:133432"
     misc_feature    order(889062..889064,889152..889154)
                     /locus_tag="Smed_4393"
                     /note="divalent metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:133432"
     misc_feature    order(889119..889121,889128..889130,889176..889178,
                     889185..889187,889626..889628,889662..889664,
                     889719..889724,889728..889730,889734..889745)
                     /locus_tag="Smed_4393"
                     /note="tetramer (dimer of dimers) interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:133432"
     misc_feature    order(889254..889256,889260..889262,889269..889277,
                     889311..889313,889317..889322,889758..889763,
                     889782..889784,889794..889796,889815..889817,
                     889839..889841,889848..889853,889881..889886,
                     889890..889892,889896..889898)
                     /locus_tag="Smed_4393"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:133432"
     gene            889946..890905
                     /locus_tag="Smed_4394"
                     /db_xref="GeneID:5319159"
     CDS             889946..890905
                     /locus_tag="Smed_4394"
                     /note="PFAM: PfkB domain protein;
                     KEGG: sme:SMb21462 putative sugar kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase-like domain-containing protein"
                     /protein_id="YP_001313131.1"
                     /db_xref="GI:150376535"
                     /db_xref="InterPro:IPR002173"
                     /db_xref="InterPro:IPR011611"
                     /db_xref="GeneID:5319159"
                     /translation="MVVNDNGVRSRYDVMVVGEYYFDLIFRGLPEVPKISADLWAEEF
                     EWVPGAAYSTALGFARLGTSAGWWCQFGTDIFSRMIVDQARSENIDDRLFIHLDRPLR
                     RVSAAFSFAHDRGFISYAEEPDPLPTPEDLARIRPRILLLQGFSLDDERRRLIEAARS
                     LGITVCSDCQHVDYRLSTPGMEEMLGLIDVFLPNASEAKALTGEDDVERALSSIARFC
                     PTVVIKCGADGAIAASKGRTTRMPALAVAVFDTTGAGDSFNAGFVHGLLTEPDIEGAI
                     ELGVICGSLAVTGYGGRNLPFKEDLTQYRRREPRYSLRSQENK"
     misc_feature    889982..890824
                     /locus_tag="Smed_4394"
                     /note="Sugar kinases, ribokinase family [Carbohydrate
                     transport and metabolism]; Region: RbsK; COG0524"
                     /db_xref="CDD:223598"
     misc_feature    889982..890824
                     /locus_tag="Smed_4394"
                     /note="Ribokinase-like subgroup A.  Found in bacteria and
                     archaea, this subgroup is part of the ribokinase/pfkB
                     superfamily.  Its oligomerization state is unknown at this
                     time; Region: ribokinase_group_A; cd01942"
                     /db_xref="CDD:238917"
     misc_feature    order(890102..890104,890702..890704,890711..890713)
                     /locus_tag="Smed_4394"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238917"
     misc_feature    order(890525..890527,890615..890617,890696..890698,
                     890705..890710,890717..890719,890783..890785,
                     890792..890794)
                     /locus_tag="Smed_4394"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238917"
     gene            890916..892178
                     /locus_tag="Smed_4395"
                     /db_xref="GeneID:5319160"
     CDS             890916..892178
                     /locus_tag="Smed_4395"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb21461 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313132.1"
                     /db_xref="GI:150376536"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5319160"
                     /translation="MKHLLKTLAGMTVIAVVSAFPAKADTVSMFCSATDYELCEKAVQ
                     KWTKETGHDVKLNRMPQNLDDAIPIYQQLFAAQSTDMDVLYIDVIWLGMFKDHLLDLT
                     SLVPEEEVKAHFASAADAARLDGKLLSMPFYIDTGLMFYRKDLLEKYGKQPPKTWDEL
                     TATAKEIQDAERKVGSPDIWGYAWQGRSYEGLTCDALEWIASAGGGTILSDDGEVTIN
                     NPKTEAALSRARGWIGTISPEGVLNYDEENSRALFESGNAVFHRNWPYVWGTSQAEGG
                     KLVGKVGVSALPVGAEGQKSSGALGTAYLGVSKYSKNPELAAELLRYMVGAEDQKMRA
                     IEGGYNPTVEALYEDADVLAKIPFLGMAKTAFEESVARPSAATGKNYNRVSRTFYRAV
                     HDIISGKDDVAKELADLERRLERDVKAK"
     misc_feature    890916..892175
                     /locus_tag="Smed_4395"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     sig_peptide     890916..890990
                     /locus_tag="Smed_4395"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 25"
     misc_feature    891033..891908
                     /locus_tag="Smed_4395"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     gene            892367..893479
                     /locus_tag="Smed_4396"
                     /db_xref="GeneID:5319161"
     CDS             892367..893479
                     /locus_tag="Smed_4396"
                     /note="PFAM: ABC transporter related; Transport-associated
                     OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21460 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313133.1"
                     /db_xref="GI:150376537"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5319161"
                     /translation="MASVTLRNVSKTFGTYDVIRSIDLEIEDGEFVVFVGPSGCGKST
                     LLRLIAGLVPVSGGDVFIGGDQVTDVPASKRGLAFVFQSYALYPHMNVARNIGFALET
                     ARLGKDEMRRRVARVADMLKIGHLLERRPRQLSGGQRQRVAIGRALVGQPEVFLFDEP
                     LSNLDADLRMEMRFEIAKLHADVRTTMIYVTHDQTEAMTLADRIVILNHGKIEQVGRP
                     RALYDRPANRFVAGFLGSPRMNFAPLETAGAAVSMLRGAGGFTYAADLAAAEGTPVEL
                     GLRPESLQLVGADVKGAIRGTFERMEDLGYEYVCYVRLTETLVWTIRATGSPPQITPG
                     EPVGLTWQPESLYLFGEDGRRIDHRTSIPLSLGASS"
     misc_feature    892367..893422
                     /locus_tag="Smed_4396"
                     /note="ABC-type sugar transport systems, ATPase components
                     [Carbohydrate transport and metabolism]; Region: MalK;
                     COG3839"
                     /db_xref="CDD:226359"
     misc_feature    892376..893014
                     /locus_tag="Smed_4396"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    892472..892495
                     /locus_tag="Smed_4396"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    order(892481..892486,892490..892498,892610..892612,
                     892838..892843,892940..892942)
                     /locus_tag="Smed_4396"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    892601..892612
                     /locus_tag="Smed_4396"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    892766..892795
                     /locus_tag="Smed_4396"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    892826..892843
                     /locus_tag="Smed_4396"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    892850..892861
                     /locus_tag="Smed_4396"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    892928..892948
                     /locus_tag="Smed_4396"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     misc_feature    893192..893413
                     /locus_tag="Smed_4396"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            893476..894369
                     /locus_tag="Smed_4397"
                     /db_xref="GeneID:5319162"
     CDS             893476..894369
                     /locus_tag="Smed_4397"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21459 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313134.1"
                     /db_xref="GI:150376538"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319162"
                     /translation="MNAARRMERQQHRTAWLFLLPLLLTLAAVAIWPLGRSIFFSFTD
                     AYLDAPSDYGFVGFDNFVEVADDPVFWGAVTNTLVFTLVSVALETLLGLAIALLLHRA
                     FLGRGIVRAAILIPWAMPMVVSARIWEWMLNDQFGLINKLLVALGLVEKGIAWTADPS
                     FILGTVIFIDVWVTTPFMVLLILAGLQLIPEEIYEAAEVSGVPHWKRFWSITLPLAMP
                     AIGVAILFRTLDALRMFDLSYVLAANNENTMTMSIYARDQLISFQDLGLGAAASTWVF
                     MIIGMIAIVIVGLLRLDRAAG"
     sig_peptide     893476..893568
                     /locus_tag="Smed_4397"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.842) with cleavage site probability 0.776 at
                     residue 31"
     misc_feature    893782..894303
                     /locus_tag="Smed_4397"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(893800..893811,893815..893844,893902..893907,
                     893911..893913,893986..893991,893995..893997,
                     894004..894006,894013..894018,894022..894024,
                     894034..894039,894046..894048,894097..894099,
                     894139..894144,894151..894153,894172..894183,
                     894190..894195,894232..894237,894265..894270,
                     894277..894282,894286..894291,894298..894303)
                     /locus_tag="Smed_4397"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(893818..893850,893902..893913,894172..894189)
                     /locus_tag="Smed_4397"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(893911..893913,893971..893973,894190..894192,
                     894226..894228,894235..894237,894265..894267)
                     /locus_tag="Smed_4397"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(894049..894087,894103..894108,894118..894120)
                     /locus_tag="Smed_4397"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            894374..895252
                     /locus_tag="Smed_4398"
                     /db_xref="GeneID:5319163"
     CDS             894374..895252
                     /locus_tag="Smed_4398"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21458 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313135.1"
                     /db_xref="GI:150376539"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319163"
                     /translation="MAMTASTAGRRYSNATYRAMRRLKTVGLYAGVAAVLAYMLFPYY
                     WAIVSSTKTGQALYQFTLLPALDFSNYWQLFNNPVFMGALVNSGVVALVSTAISLVIG
                     ILGAYALGRLHFPPGRMVLIAVLMISVFPQVVVLSGMFEVIGWLGLYNRPSGLIVSYL
                     ILTLPFTTWILTSFIRDLPKELEEAALVDGCSRLRILTHVLLPLMGPAIASTGLLSFI
                     LAWNEFLFALTFILTDENRTVPVAIGLLTGSSRYEYPFGQIMAASVTVTLPLLALVLV
                     FQRKIVAGLTSGAVKG"
     misc_feature    894488..895246
                     /locus_tag="Smed_4398"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    894623..895069
                     /locus_tag="Smed_4398"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(894671..894676,894683..894688,894701..894703,
                     894731..894742,894746..894775,894782..894787,
                     894791..894793,894863..894865,894869..894871,
                     894878..894883,894887..894889,894899..894904,
                     894911..894913,894962..894964,895004..895009,
                     895016..895018,895037..895048,895055..895060)
                     /locus_tag="Smed_4398"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(894749..894793,895037..895054)
                     /locus_tag="Smed_4398"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(894791..894793,894851..894853,895055..895057)
                     /locus_tag="Smed_4398"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(894914..894952,894968..894973,894983..894985)
                     /locus_tag="Smed_4398"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            895487..895924
                     /locus_tag="Smed_4399"
                     /db_xref="GeneID:5319164"
     CDS             895487..895924
                     /locus_tag="Smed_4399"
                     /note="KEGG: sme:SMb21456 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313136.1"
                     /db_xref="GI:150376540"
                     /db_xref="GeneID:5319164"
                     /translation="MKHQAIEQLQGVAEVKQDFPRRTLSRKERLERWAELLERDPHRR
                     LSTLHETEYQPARVRAAMRGDGSPISVAFEDPVFRAAGMENDSYGEARRFFELSDEQL
                     HKVICYCHFGATVSASTASRHIRAMLIEKQPGLFARLRQMFAG"
     gene            896185..897462
                     /locus_tag="Smed_4400"
                     /db_xref="GeneID:5319165"
     CDS             896185..897462
                     /locus_tag="Smed_4400"
                     /note="PFAM: protein of unknown function DUF763;
                     KEGG: sme:SMb21455 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313137.1"
                     /db_xref="GI:150376541"
                     /db_xref="InterPro:IPR008482"
                     /db_xref="GeneID:5319165"
                     /translation="MAQRAGNADLPLHGGRVPRWLGDRMTRLGALVTEAIVHHYGRDE
                     FLRRLAHPFWFQSFGAVMGMDWHSSGITTSVIGALKRGLTPLAGELGIHVCGGRGQHS
                     RKTPGELVSIGDRIGFDGGAMAEASRLVAKVDSAAVQDGFDLYLHGFIITDDAKWVVV
                     QQGMNGDRRQARRYHWLSEGLTSFVDAPHSAIEGRGQGEIFNLADRRAAASRSAQLDL
                     LHSLGPDGLLREVASIEARAAPQAEPAQPLLPHLFMPAHHEVRESDVNLRRLHGSFAA
                     AAERGPEDFKDLLLVPGVGARTVKALAMVAEVVHGTPCRFSDPARFSLAHGGKDRHPF
                     PVPLKVYDETIGVMKSAVSKARLGREEELAALKRLDEQSRRLERYVTGPDLKEIVAGE
                     FRDSARFGGRSIFGWEPPEEETIISEPGDRARR"
     misc_feature    896188..897327
                     /locus_tag="Smed_4400"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG1415"
                     /db_xref="CDD:224333"
     gene            897576..897845
                     /locus_tag="Smed_4401"
                     /db_xref="GeneID:5319166"
     CDS             897576..897845
                     /locus_tag="Smed_4401"
                     /note="KEGG: sme:SMb21454 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313138.1"
                     /db_xref="GI:150376542"
                     /db_xref="GeneID:5319166"
                     /translation="MTAAMTTTNHDTIRKWIEAREGQPARVKNANEGGGGLLRVDFGK
                     PEDTLEKISWDEFFKIFDEEKLAFLHQDMTEDGQTSRFCKFVNRD"
     gene            897897..898091
                     /locus_tag="Smed_4402"
                     /db_xref="GeneID:5319167"
     CDS             897897..898091
                     /locus_tag="Smed_4402"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313139.1"
                     /db_xref="GI:150376543"
                     /db_xref="GeneID:5319167"
                     /translation="MGKDLVMLATRKPEPAAEREERPVRPAVDDEPAPAAIRRAATDA
                     RESLHEPNALFWRGIWMTLF"
     gene            complement(898088..898432)
                     /locus_tag="Smed_4403"
                     /db_xref="GeneID:5318116"
     CDS             complement(898088..898432)
                     /locus_tag="Smed_4403"
                     /note="KEGG: sme:SMb21452 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313140.1"
                     /db_xref="GI:150376544"
                     /db_xref="GeneID:5318116"
                     /translation="MSTNKPGEPRPGGDARPLDPPSVDEPIDAWERDRMGAPDIGREL
                     DGLRERIARLQAEIDTIATETHTAIGTVPGGDRLEAARDVVAEKRDEIKRLTARLGEI
                     ERNVGDAGQERL"
     misc_feature    complement(<898091..898294)
                     /locus_tag="Smed_4403"
                     /note="UV radiation resistance protein and
                     autophagy-related subunit 14; Region: Atg14; pfam10186"
                     /db_xref="CDD:220623"
     gene            898573..898788
                     /locus_tag="Smed_4404"
                     /db_xref="GeneID:5318117"
     CDS             898573..898788
                     /locus_tag="Smed_4404"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313141.1"
                     /db_xref="GI:150376545"
                     /db_xref="GeneID:5318117"
                     /translation="MHSEEYLELHYDLLSHRALLSCGRNAYVLPDIYETKEMAQVAAQ
                     KFAWETLGLKERAAGCRTAADLPVWLR"
     gene            complement(898827..899342)
                     /locus_tag="Smed_4405"
                     /db_xref="GeneID:5318118"
     CDS             complement(898827..899342)
                     /locus_tag="Smed_4405"
                     /note="KEGG: sme:SMb21450 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313142.1"
                     /db_xref="GI:150376546"
                     /db_xref="GeneID:5318118"
                     /translation="MKVEEFIFAESGGVPNNPRLPVLVYRQAIDVTENAATRIEQRFR
                     ANGWLGLWRNGVFAHHHYHCGAHEVLGIAEGRARLLIGGPGGREVEVAAGDVILLPAG
                     TGHRRDEASADFLVIGGYPPEQHADIKSGAATADDRIAIDAVPLPRFDPVLGAEGPAV
                     IVWHSAMHARS"
     misc_feature    complement(898854..899342)
                     /locus_tag="Smed_4405"
                     /note="Uncharacterized protein containing double-stranded
                     beta helix domain [Function unknown]; Region: COG4297"
                     /db_xref="CDD:226747"
     gene            899493..900215
                     /locus_tag="Smed_4406"
                     /db_xref="GeneID:5318119"
     CDS             899493..900215
                     /locus_tag="Smed_4406"
                     /note="KEGG: sme:SMb21449 probable glutathione
                     S-transferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glutathione S-transferase"
                     /protein_id="YP_001313143.1"
                     /db_xref="GI:150376547"
                     /db_xref="GeneID:5318119"
                     /translation="MSYKLYYWDGIPGRGEFVRLALEEGGADYVDAAREPGGTDEMLK
                     LMKAPGGAAPPFAPPFLVDGDLLIAHVANILFYLGPRLGLAPEGEGLRTIANGLQLTI
                     TDFVAEIHDTHHPIGVSHYYESQKPEALRRAADFLSERLPKFLGYFERVLSQNSSGPN
                     QMVGDRLSYVDLSLFQVIEGLRYAFPRAMDAYEANIPRLVDVHDAVRVRPRIYSYLAS
                     ERRLAFNESCIFRHYPELDRQS"
     misc_feature    899499..899729
                     /locus_tag="Smed_4406"
                     /note="GST_N family, Class Sigma_like; composed of GSTs
                     belonging to class Sigma and similar proteins, including
                     GSTs from class Mu, Pi and Alpha. GSTs are cytosolic
                     dimeric proteins involved in cellular detoxification by
                     catalyzing the conjugation of...; Region:
                     GST_N_Sigma_like; cd03039"
                     /db_xref="CDD:239337"
     misc_feature    899505..900152
                     /locus_tag="Smed_4406"
                     /note="glutathione s-transferase; Provisional; Region:
                     PTZ00057"
                     /db_xref="CDD:173353"
     misc_feature    order(899511..899513,899532..899534,899661..899669,
                     899700..899705)
                     /locus_tag="Smed_4406"
                     /note="GSH binding site (G-site) [chemical binding]; other
                     site"
                     /db_xref="CDD:239337"
     misc_feature    order(899517..899519,899526..899534,899538..899543,
                     899547..899552,899559..899564,899589..899591,
                     899706..899708,899718..899720,899727..899729)
                     /locus_tag="Smed_4406"
                     /note="C-terminal domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239337"
     misc_feature    order(899658..899660,899697..899702,899706..899708,
                     899718..899720)
                     /locus_tag="Smed_4406"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239337"
     misc_feature    899766..900110
                     /locus_tag="Smed_4406"
                     /note="C-terminal, alpha helical domain of Class
                     Sigma-like Glutathione S-transferases; Region:
                     GST_C_Sigma_like; cd03192"
                     /db_xref="CDD:198301"
     misc_feature    order(899766..899768,899778..899783,899790..899795,
                     899802..899804)
                     /locus_tag="Smed_4406"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:198301"
     misc_feature    order(899778..899780,899787..899789,899799..899801,
                     899997..899999,900009..900011,900018..900020,
                     900030..900032)
                     /locus_tag="Smed_4406"
                     /note="N-terminal domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:198301"
     misc_feature    order(899799..899801,899808..899813,899820..899825,
                     900021..900023,900030..900032)
                     /locus_tag="Smed_4406"
                     /note="substrate binding pocket (H-site) [chemical
                     binding]; other site"
                     /db_xref="CDD:198301"
     gene            complement(900219..900860)
                     /locus_tag="Smed_4407"
                     /db_xref="GeneID:5318120"
     CDS             complement(900219..900860)
                     /locus_tag="Smed_4407"
                     /note="TIGRFAM: phage SPO1 DNA polymerase-related protein;
                     PFAM: Uracil-DNA glycosylase superfamily;
                     KEGG: sme:SMb21448 putative DNA polymerase related
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phage SPO1 DNA polymerase-like protein"
                     /protein_id="YP_001313144.1"
                     /db_xref="GI:150376548"
                     /db_xref="InterPro:IPR005122"
                     /db_xref="InterPro:IPR005273"
                     /db_xref="GeneID:5318120"
                     /translation="MPRESAKLGPALAGEHAEAPTIASLRREAEGCERCDLYKNATQL
                     VFGEGPTDARVVLVGEQPGDREDLAGRPFVGPAGRLLDECMHEAGIDRSECYLTNAVK
                     HFKFEPRGKRRLHSRPNAGEVQACAWWLGAEIDELRPEIVVALGATALMSLLGRGVGV
                     TKNRGQFVPAPGGFSVLVTIHPSYLLRIRGRGDPEAERARFVDDLAKVAVRIG"
     misc_feature    complement(900234..900767)
                     /locus_tag="Smed_4407"
                     /note="Family 4 Uracil-DNA glycosylase (UDG), found
                     exclusively in thermophilic organisms; Region:
                     UDG_F4_TTUDGA_like; cd10030"
                     /db_xref="CDD:198428"
     misc_feature    complement(order(900474..900476,900483..900488,
                     900552..900560,900738..900740,900747..900752,
                     900756..900761,900765..900767))
                     /locus_tag="Smed_4407"
                     /note="Fe-S cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:198428"
     misc_feature    complement(order(900318..900320,900564..900566,
                     900642..900647,900663..900665,900678..900686))
                     /locus_tag="Smed_4407"
                     /note="active site"
                     /db_xref="CDD:198428"
     gene            complement(900951..902756)
                     /locus_tag="Smed_4408"
                     /db_xref="GeneID:5318121"
     CDS             complement(900951..902756)
                     /locus_tag="Smed_4408"
                     /note="TIGRFAM: malto-oligosyltrehalose trehalohydrolase;
                     PFAM: glycoside hydrolase family 13 domain protein; alpha
                     amylase catalytic region;
                     SMART: alpha amylase catalytic sub domain;
                     KEGG: sme:SMb21447 putative 1,4-alpha-glucan branching
                     enzyme protein"
                     /codon_start=1
                     /transl_table=11
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="YP_001313145.1"
                     /db_xref="GI:150376549"
                     /db_xref="InterPro:IPR004193"
                     /db_xref="InterPro:IPR006047"
                     /db_xref="InterPro:IPR006589"
                     /db_xref="InterPro:IPR012768"
                     /db_xref="GeneID:5318121"
                     /translation="MRESSTPPCFRKTWGPNFVGEDTCRFRLWAPDERGVDLVLDGTP
                     HEMRQSDGGWFEITVETKPGDRYCFRLADGTEVADPASSAQERGAEGASLVVDQAAYE
                     WRAASWRGRPWEEAVISELHIGCFTPEGTFRAAINRLPHLASAGITAIEIMPVAQFPG
                     ARGWGYDGVLHYAPHNAYGTPDDLKGLVDAAHSLGLMVLLDVVYNHFGPEQNYLSLYA
                     SRFFNKDRPTPWGASIAFEEEAVRRYFIENALYWLGDFRFDGLRLDATEQIRDTSNPH
                     FLVALEHEVRKCFADRQIHLVVEDANRRRSLLERDANGTPMLFDAAWNDDLHNALHVV
                     ATGETRGHYRPFAEAPWSKIRSALAEGFAVPAKEDNFSAEGSRARVPPQGRVNFLQNH
                     DQIGNRAFGERLASLVREDSLRVLTAMHMLAPQIPLLFMGEEYGETQPFYFFSDYQGE
                     IADAIRLGRRDEAENFGGLPNGKTVEDLPDPLDPEVFSGSKLRWSRAASPAGERRLAY
                     MRDLASIRQRHIVPMMAGTAMPEHRAFETEDGVIAVDWQFGESCLEMRVNLSQETHAM
                     PPFRGQPIFASEAAGERTPDVTELAGLGIVVAIAR"
     misc_feature    complement(902469..902714)
                     /locus_tag="Smed_4408"
                     /note="N-terminal Early set domain associated with the
                     catalytic domain of Maltooligosyl trehalose
                     trehalohydrolase (also called Glycosyltrehalose
                     trehalohydrolase) and similar proteins; Region:
                     E_set_MTHase_like_N; cd02853"
                     /db_xref="CDD:199883"
     misc_feature    complement(901056..902687)
                     /locus_tag="Smed_4408"
                     /note="malto-oligosyltrehalose trehalohydrolase; Region:
                     trehalose_TreZ; TIGR02402"
                     /db_xref="CDD:233850"
     misc_feature    complement(901200..902522)
                     /locus_tag="Smed_4408"
                     /note="Alpha amylase catalytic domain found in
                     Glycosyltrehalose trehalohydrolase (also called
                     Maltooligosyl trehalose Trehalohydrolase); Region:
                     AmyAc_GTHase; cd11325"
                     /db_xref="CDD:200464"
     misc_feature    complement(order(901578..901580,901860..901862,
                     901965..901967))
                     /locus_tag="Smed_4408"
                     /note="catalytic site [active]"
                     /db_xref="CDD:200464"
     misc_feature    complement(order(901566..901568,901575..901580,
                     901770..901772,901782..901784,901854..901856,
                     901860..901862))
                     /locus_tag="Smed_4408"
                     /note="active site"
                     /db_xref="CDD:200464"
     misc_feature    complement(900966..901235)
                     /locus_tag="Smed_4408"
                     /note="Domain of unknown function (DUF3459); Region:
                     DUF3459; pfam11941"
                     /db_xref="CDD:221332"
     gene            902901..904988
                     /locus_tag="Smed_4409"
                     /db_xref="GeneID:5318122"
     CDS             902901..904988
                     /locus_tag="Smed_4409"
                     /note="TIGRFAM: glycogen debranching enzyme GlgX;
                     PFAM: glycoside hydrolase family 13 domain protein; alpha
                     amylase catalytic region;
                     SMART: alpha amylase catalytic sub domain;
                     KEGG: sme:SMb21446 probable glycosyl hydrolase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="YP_001313146.1"
                     /db_xref="GI:150376550"
                     /db_xref="InterPro:IPR004193"
                     /db_xref="InterPro:IPR006047"
                     /db_xref="InterPro:IPR006589"
                     /db_xref="InterPro:IPR011837"
                     /db_xref="GeneID:5318122"
                     /translation="MNLAFTELDFIKPELGADYTGQGTHFAVFSAHAEKIELCLFSED
                     GREETARMPLPKREGDVWSGYIEGIGPGALYGYRAHGPYDPHKGHRFNPNKLLLDPYA
                     KQVAGELIWDDALFGYTIGSPDGDLSFDERDSAPFMVKGVVQDPAFDWAGEEAIRRPW
                     TETVIYEAHVRGMTMTHPAVPDELRGTFLGMASDPIIEHLVKLGVSAIELMPVQYFLD
                     DRYLIERNLRNYWGYQTLGFFAPHKRYLRGDRITEFKTMVKRFHAVGIEVLMDVVYNH
                     TAEGSERGPTLSFRGLDNFSYYRQSPDKPRHTYDTTGTGNTLNVAHPLVLRMVLDSLR
                     YWVGVMHIDGFRFDLASTLGREYMEFDREGGFFDAIRQDPILAGVKLIAEPWDVGQGG
                     YQLGGFPPPFREWNDQFRDDVRRFWRGDAGMVPVLAERLVGSPVQFRHSDRAATSSIN
                     LVSAHDGFTLMDTVSYGEKHNEANGEENRDGHSDNHSDNMGAEGPTDNAEVNEARRRR
                     RAAMVATLMVSQGVPMVLGGDELGNSQRGNNNAYCQDNEIGWLDWPGADEGFLDFCRK
                     LIAFRKQSPVLRQERFLDGEPDENGRVEIAWYKADGTPMDEDAWHTGELRLICAYICR
                     TGQDEASPVGEIVVVLNAGEGCEIVLPHANGTKHWLRVLDTAAEEPFDMRASADRESI
                     PAQSLVAYVPQEG"
     misc_feature    902934..904976
                     /locus_tag="Smed_4409"
                     /note="glycogen debranching enzyme GlgX; Region:
                     glgX_debranch; TIGR02100"
                     /db_xref="CDD:131155"
     misc_feature    902943..903335
                     /locus_tag="Smed_4409"
                     /note="N-terminal Early set domain associated with the
                     catalytic domain of Glycogen debranching enzyme and
                     bacterial isoamylase (also called glycogen
                     6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N;
                     cd02856"
                     /db_xref="CDD:199886"
     misc_feature    903342..904619
                     /locus_tag="Smed_4409"
                     /note="Alpha amylase catalytic domain found in glycogen
                     debranching enzymes; Region: AmyAc_Glg_debranch; cd11326"
                     /db_xref="CDD:200465"
     misc_feature    order(903936..903938,903942..903947,904050..904052,
                     904263..904268)
                     /locus_tag="Smed_4409"
                     /note="active site"
                     /db_xref="CDD:200465"
     misc_feature    order(903942..903944,904050..904052,904266..904268)
                     /locus_tag="Smed_4409"
                     /note="catalytic site [active]"
                     /db_xref="CDD:200465"
     gene            904990..906108
                     /locus_tag="Smed_4410"
                     /db_xref="GeneID:5318123"
     CDS             904990..906108
                     /locus_tag="Smed_4410"
                     /note="KEGG: sme:SMb21445 putative DNA topoisomerase I
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA topoisomerase I protein"
                     /protein_id="YP_001313147.1"
                     /db_xref="GI:150376551"
                     /db_xref="InterPro:IPR001631"
                     /db_xref="GeneID:5318123"
                     /translation="MARAMSVDVLECRPAGLADLPQRLAAIGSVPEETGLVYVSDSEP
                     GIRRQRRGKGFAYRMPDGSIVTDPSVKSRIAALGLPPAYENVWICLDERGHLQATGYD
                     ARGRKQYRYHSEWQALRSADKFAQLTEFGKALPKIRRTIRRHMQGGVENMQTVLAALV
                     ALLDEAHLRTGNQAYVQANGSYGATTLLKRHLRLGDGFIELKFTGKGGKRVQRVLRRP
                     KLQRLLEEIADLPGRQLFVWKDENDALRPVDSGRLNRYLTDMAGTAISAKTFRTWGGT
                     LAAFTVARTSIERGEWPTIKQMSEAAASVLHNTPAISRSSYIHPDVLALADKSAPVSA
                     RQLQARGRSGSELRVEEQRLLGFLQRSAGTKKRLPLPQ"
     misc_feature    905080..906090
                     /locus_tag="Smed_4410"
                     /note="Topoisomerase IB [DNA replication, recombination,
                     and repair]; Region: COG3569"
                     /db_xref="CDD:226099"
     misc_feature    905290..905976
                     /locus_tag="Smed_4410"
                     /note="Eukaryotic DNA topoisomerase I, catalytic core;
                     Region: Topoisom_I; pfam01028"
                     /db_xref="CDD:216252"
     misc_feature    order(905494..905496,905791..905793,905800..905802,
                     905911..905913,905938..905940)
                     /locus_tag="Smed_4410"
                     /note="active site"
                     /db_xref="CDD:238231"
     misc_feature    order(905494..905499,905605..905607,905785..905793,
                     905938..905940)
                     /locus_tag="Smed_4410"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238231"
     misc_feature    order(905494..905496,905605..905607,905791..905793,
                     905800..905802,905911..905913,905938..905940)
                     /locus_tag="Smed_4410"
                     /note="Int/Topo IB signature motif; other site"
                     /db_xref="CDD:238231"
     gene            complement(906237..906971)
                     /locus_tag="Smed_4411"
                     /db_xref="GeneID:5318124"
     CDS             complement(906237..906971)
                     /locus_tag="Smed_4411"
                     /note="PFAM: transport-associated;
                     SMART: Transport-associated and nodulation region;
                     KEGG: sme:SMb21444 osmotic sensory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transport-associated protein"
                     /protein_id="YP_001313148.1"
                     /db_xref="GI:150376552"
                     /db_xref="InterPro:IPR007055"
                     /db_xref="InterPro:IPR014004"
                     /db_xref="GeneID:5318124"
                     /translation="MPRQPDYGRYDPYTRRDWPRRDWENERSRDPYHGSERNRGRGRG
                     RLGEEVEPRGADYENSMSWPTGSYRSESERWSDDDDDRRGRERYFRDYHGPGYGYRGE
                     GRYRGYGGYGETRDYRRGDRDFLDRASDEVASWFGDEDAERRREMDRHRGKGPKGYRR
                     TDGRIQEDVSDRLSDDGALDASNIEVSVTNGEVQLNGTVSSKWAKRRAEDCAENVSGV
                     TNVQNNLRIEPDTSTVQQNPNLTDLS"
     misc_feature    complement(906285..>906602)
                     /locus_tag="Smed_4411"
                     /note="Predicted periplasmic or secreted lipoprotein
                     [General function prediction only]; Region: OsmY; COG2823"
                     /db_xref="CDD:225379"
     misc_feature    complement(906285..906443)
                     /locus_tag="Smed_4411"
                     /note="BON domain; Region: BON; pfam04972"
                     /db_xref="CDD:203137"
     gene            907111..907302
                     /locus_tag="Smed_4412"
                     /db_xref="GeneID:5318125"
     CDS             907111..907302
                     /locus_tag="Smed_4412"
                     /note="KEGG: sme:SMb21443 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313149.1"
                     /db_xref="GI:150376553"
                     /db_xref="GeneID:5318125"
                     /translation="MSWETKMPNPNQPDPAPEPPPKQAPDLPPWFPDVPIEEPEPDVL
                     PDEVPVPNPDENPEPPRHL"
     gene            907396..907704
                     /locus_tag="Smed_4413"
                     /db_xref="GeneID:5318126"
     CDS             907396..907704
                     /locus_tag="Smed_4413"
                     /note="KEGG: atc:AGR_C_2256 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313150.1"
                     /db_xref="GI:150376554"
                     /db_xref="GeneID:5318126"
                     /translation="MDNMDNVDNVGNQREELIRRRAYVIWEQEGRPDGQHERHWEQAA
                     REMQGSEPQGSEEKGKAASGSGIRTNGSRRREKQTVTETEAPASPAEGSAASRLDGER
                     "
     misc_feature    907429..907542
                     /locus_tag="Smed_4413"
                     /note="Protein of unknown function (DUF2934); Region:
                     DUF2934; pfam11154"
                     /db_xref="CDD:204599"
     gene            907763..908203
                     /locus_tag="Smed_4414"
                     /db_xref="GeneID:5318978"
     CDS             907763..908203
                     /locus_tag="Smed_4414"
                     /note="PFAM: CBS domain containing protein;
                     KEGG: sme:SMb21441 putative inosine-5'-monophosphate
                     dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313151.1"
                     /db_xref="GI:150376555"
                     /db_xref="InterPro:IPR000644"
                     /db_xref="GeneID:5318978"
                     /translation="MRVSEIMTRDVHLASPNDTIAAIAREMAENDIGFMPVGDNDRLI
                     GMITDRDIVVRGVADGVDPQARVADIMTTDVKYCFDDDDVDDVARNMGDIQVRRLPVV
                     NHDKQLVGVVSLADAAREQPQMAGTGLKGVTEPGGSHNQTHRNG"
     misc_feature    907769..908110
                     /locus_tag="Smed_4414"
                     /note="FOG: CBS domain [General function prediction only];
                     Region: COG0517"
                     /db_xref="CDD:223591"
     misc_feature    907787..908122
                     /locus_tag="Smed_4414"
                     /note="The CBS domain, named after human CBS, is a small
                     domain originally identified in cystathionine
                     beta-synthase and is subsequently found in a wide range of
                     different proteins. CBS domains usually occur in tandem
                     repeats. They associate to form a so-called...; Region:
                     CBS_pair_9; cd04622"
                     /db_xref="CDD:239994"
     gene            908292..908651
                     /locus_tag="Smed_4415"
                     /db_xref="GeneID:5318979"
     CDS             908292..908651
                     /locus_tag="Smed_4415"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313152.1"
                     /db_xref="GI:150376556"
                     /db_xref="GeneID:5318979"
                     /translation="MVVNQKSLPDRAGPIPGDAEPDEHVADAGDAGGVTRYLDQPEHP
                     DPPQPKPRNFSAFSERPAPRPASEPAEEAVAANDATGGEYWNRVLGDNTNAGTLRFLA
                     AVGLFVLIAAALFWLAG"
     gene            complement(908796..909239)
                     /locus_tag="Smed_4416"
                     /db_xref="GeneID:5318980"
     CDS             complement(908796..909239)
                     /locus_tag="Smed_4416"
                     /note="KEGG: sme:SMb21440 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313153.1"
                     /db_xref="GI:150376557"
                     /db_xref="GeneID:5318980"
                     /translation="MITRYTLVASLTVAASSLMLLNPASALELAQAQQAPAQTQPQAL
                     PDAGGTSAPISEQKIEAFAVAYLQVDKVRQEYSTKIGATTDEAAKTKLQNEASQEMVK
                     AVETSPNMSVEEYTTILKAAQSDPALAQKVQEKLQTSAPQQPQQQ"
     sig_peptide     complement(909159..909239)
                     /locus_tag="Smed_4416"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.830 at
                     residue 27"
     misc_feature    complement(908844..909080)
                     /locus_tag="Smed_4416"
                     /note="Domain of unknown function (DUF4168); Region:
                     DUF4168; pfam13767"
                     /db_xref="CDD:205940"
     gene            complement(909645..910454)
                     /locus_tag="Smed_4417"
                     /db_xref="GeneID:5318981"
     CDS             complement(909645..910454)
                     /locus_tag="Smed_4417"
                     /note="PFAM: UbiE/COQ5 methyltransferase;
                     methyltransferase small; Methyltransferase type 11;
                     Methyltransferase type 12;
                     KEGG: sme:SMb21433 putative methyl-transferase,
                     S-adenosyl-L-methionine (SAM)-MTase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="type 11 methyltransferase"
                     /protein_id="YP_001313154.1"
                     /db_xref="GI:150376558"
                     /db_xref="InterPro:IPR004033"
                     /db_xref="InterPro:IPR007848"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="GeneID:5318981"
                     /translation="MSDVATRANYDLRDEIKAYWSERAATFDLSPGHEIFSEEERAAW
                     HRLILRHLGEGAGRAALDLASGTGVVSHLLDDLGFRVTGIDWAEPMLDRARQKAKTRG
                     RNISFRMGDAENTMEPDDHYHVVVNRHLVWTLVDPSAAFREWLRVLKPGGSLLIVDGD
                     FVNATRLERFFSSLNAWGQRVGLLRPDAPSQPREMLETHRSILARVHFSQGARAEAVV
                     DLLHASGFTDIRVDTDLGEIHRMQAKNWNLFKGLARRSQHRFAIHASKPAA"
     misc_feature    complement(909891..910349)
                     /locus_tag="Smed_4417"
                     /note="Methyltransferase domain; Region: Methyltransf_23;
                     pfam13489"
                     /db_xref="CDD:222171"
     misc_feature    complement(909984..910274)
                     /locus_tag="Smed_4417"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(910071..910073,910119..910127,
                     910197..910202,910248..910268))
                     /locus_tag="Smed_4417"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            910560..911693
                     /locus_tag="Smed_4418"
                     /db_xref="GeneID:5318982"
     CDS             910560..911693
                     /locus_tag="Smed_4418"
                     /note="PFAM: periplasmic binding protein;
                     KEGG: atc:AGR_L_2862 putative iron complex transport
                     system substrate-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein"
                     /protein_id="YP_001313155.1"
                     /db_xref="GI:150376559"
                     /db_xref="InterPro:IPR002491"
                     /db_xref="GeneID:5318982"
                     /translation="MKLINMLAAAAAGFCVLISSAAFADTIKVTDVAGREVEVDVPVK
                     HVILGEGRQIYFVGALDKDEPFKRVVGWRDDLAKADPESYAAYLAKYPDIAKLPTFGG
                     MKEGTFDIEQAVALKPDVMLLNIDAKTATEEAGYIEKLEKVGIPLVYVDFREKPMENT
                     EPSMRIIGKLFGKEEKAEEFIQFRADSIVKVTVTLAKADPKKPLVFVERAGGYSEDCC
                     MSFGNENFGRMVEFAGGVNMAKDIIPGTFGTVNPEQVIASNPDQIIITGGNWEGYVPG
                     GAWVGVGYGADEKEAQLKLEALTKRPAFTGVKAVKDGNVHAIWHQFYNNPYQFVAIQQ
                     MAKWLHPDLFKDLDPEATFKELHERFLPLPYKSGYFVSLNVSQ"
     sig_peptide     910560..910634
                     /locus_tag="Smed_4418"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 25"
     misc_feature    910566..911678
                     /locus_tag="Smed_4418"
                     /note="ferrichrome/ferrioxamine B periplasmic transporter;
                     Provisional; Region: PRK14048"
                     /db_xref="CDD:172540"
     misc_feature    910638..911669
                     /locus_tag="Smed_4418"
                     /note="Periplasmic binding protein TroA_f.  These proteins
                     are predicted to function as initial receptors in the ABC
                     metal ion uptake in eubacteria and archaea.  They belong
                     to the TroA superfamily of helical backbone metal receptor
                     proteins that share a...; Region: TroA_f; cd01139"
                     /db_xref="CDD:238559"
     misc_feature    order(910710..910715,910785..910787,910869..910871,
                     910926..910928,910932..910934,911145..911147,
                     911253..911255)
                     /locus_tag="Smed_4418"
                     /note="putative ligand binding residues [chemical
                     binding]; other site"
                     /db_xref="CDD:238559"
     gene            911823..912890
                     /locus_tag="Smed_4419"
                     /db_xref="GeneID:5318983"
     CDS             911823..912890
                     /locus_tag="Smed_4419"
                     /note="PFAM: transport system permease protein;
                     KEGG: sme:SMb21430 putative iron ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transport system permease"
                     /protein_id="YP_001313156.1"
                     /db_xref="GI:150376560"
                     /db_xref="InterPro:IPR000522"
                     /db_xref="GeneID:5318983"
                     /translation="MTAIAEEIAGIEGRGRYRALVVRRLVMLSGLLAALFVSVAVDMA
                     LGPANYPLSDVLTALFWAETVGDQLRVVIWDIRMPIALMAVTVGASLSLAGAQMQTIL
                     ANPLASPFTLGISAAAGFGAALGLVAGVAVFPVAVQYMVPINAFLMAMVAALFIHFAS
                     TMRGVTVETIVLLGIALVFTFNAALSLLEYLASEQALAAVVFWTMGSLTKATWPKVWV
                     TAAVLLVAVPVFARRAWALTALRLGEDKAASFGIDVGRLRLETMLTVSLLAAIPVSFV
                     GTIGFVGLVGPHIARMLVGEDQRFFLPASVLCGSLLLSVTSVVSKTLIPGAVLPIGII
                     TALVGVPFFFVLIFTNRKRAW"
     misc_feature    911862..912881
                     /locus_tag="Smed_4419"
                     /note="ABC-type enterobactin transport system, permease
                     component [Inorganic ion transport and metabolism];
                     Region: FepG; COG4779"
                     /db_xref="CDD:227119"
     misc_feature    912066..912863
                     /locus_tag="Smed_4419"
                     /note="Transmembrane subunit (TM), of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters involved in the uptake of siderophores, heme,
                     vitamin B12, or the divalent cations Mg2+ and Zn2+.
                     PBP-dependent ABC transporters consist of...; Region:
                     TM_ABC_iron-siderophores_like; cd06550"
                     /db_xref="CDD:119348"
     misc_feature    order(912117..912119,912129..912137,912513..912518,
                     912522..912530,912534..912539,912543..912560,
                     912564..912572,912693..912695,912714..912716)
                     /locus_tag="Smed_4419"
                     /note="ABC-ATPase subunit  interface; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(912132..912134,912138..912140,912153..912155,
                     912327..912329,912333..912338,912345..912350,
                     912357..912362,912369..912371,912378..912383,
                     912387..912389,912423..912428,912435..912437,
                     912663..912665,912819..912821,912828..912833,
                     912840..912842,912849..912854,912861..912863)
                     /locus_tag="Smed_4419"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(912387..912389,912465..912467,912639..912641,
                     912651..912653,912783..912785,912810..912812)
                     /locus_tag="Smed_4419"
                     /note="putative PBP binding regions; other site"
                     /db_xref="CDD:119348"
     gene            912884..913645
                     /locus_tag="Smed_4420"
                     /db_xref="GeneID:5318984"
     CDS             912884..913645
                     /locus_tag="Smed_4420"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21429 putative iron ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313157.1"
                     /db_xref="GI:150376561"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318984"
                     /translation="MVSLALKDVGATYGRRVVLSDINTGVLKGGQLTAVIGPNAAGKS
                     TLFKRIAGLAAGPGLVHLSDTAKGSEAICYMPQDTGANAVLTVYESVLLSAKQGSGWK
                     VKDGELQEIDRVLAALKINELAFRGLGELSGGQRQLVSIAQALVRKPEVLLMDEPTSA
                     LDLFRQIEVLGFMKRLATQSGMAVLIALHDLNHALRYCEDTIVISDGSVVASGPTHAV
                     VTADMLKSVYRVEARVEACSRGRPVIIVDDSIALG"
     misc_feature    912890..913630
                     /locus_tag="Smed_4420"
                     /note="ABC-type cobalamin/Fe3+-siderophores transport
                     systems, ATPase components [Inorganic ion transport and
                     metabolism / Coenzyme metabolism]; Region: FepC; COG1120"
                     /db_xref="CDD:224045"
     misc_feature    912896..913522
                     /locus_tag="Smed_4420"
                     /note="ATP-binding component of iron-siderophores, vitamin
                     B12 and hemin transporters and related proteins; Region:
                     ABC_Iron-Siderophores_B12_Hemin; cd03214"
                     /db_xref="CDD:213181"
     misc_feature    912992..913015
                     /locus_tag="Smed_4420"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213181"
     misc_feature    order(913001..913006,913010..913018,913112..913114,
                     913346..913351,913448..913450)
                     /locus_tag="Smed_4420"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213181"
     misc_feature    913103..913114
                     /locus_tag="Smed_4420"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213181"
     misc_feature    913274..913303
                     /locus_tag="Smed_4420"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213181"
     misc_feature    913334..913351
                     /locus_tag="Smed_4420"
                     /note="Walker B; other site"
                     /db_xref="CDD:213181"
     misc_feature    913358..913369
                     /locus_tag="Smed_4420"
                     /note="D-loop; other site"
                     /db_xref="CDD:213181"
     misc_feature    913436..913456
                     /locus_tag="Smed_4420"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213181"
     gene            complement(913697..914086)
                     /locus_tag="Smed_4421"
                     /pseudo
                     /db_xref="GeneID:5318985"
     gene            914413..915852
                     /locus_tag="Smed_4422"
                     /db_xref="GeneID:5318986"
     CDS             914413..915852
                     /locus_tag="Smed_4422"
                     /note="PFAM: FAD linked oxidase domain protein;
                     Berberine/berberine domain protein;
                     KEGG: sme:SMb21415 putative oxidoreductase, oxygen
                     dependent, FAD-dependent protein"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD linked oxidase domain-containing protein"
                     /protein_id="YP_001313158.1"
                     /db_xref="GI:150376562"
                     /db_xref="InterPro:IPR006093"
                     /db_xref="InterPro:IPR006094"
                     /db_xref="InterPro:IPR012951"
                     /db_xref="GeneID:5318986"
                     /translation="MNDMSLTNLQNGITMVSAAAIEAFAGRLRGRVLMATDAAYDEAR
                     TVWNGMIDRRPGLIVQCAGAADVVNAVRFAAENQLLLAVRGGGHNIAGNAVCDGGLVI
                     DLTPMKSIRVDQTTKTAWVEPGATLAEVDMETQAFRLGLPTGINSTTGIAGLTLGGGF
                     GWITRKFGLTIDNLLSADVVTANGELVRASPTEHRDLFWAIRGGGGNFGVVTAFEFRL
                     HELGPEVLSGLVVHPFADAESVLQQYRQALENAPDELTCWVVMRQAPPLPFLPADWHG
                     KEVVVLAMCHCGDLEAGEKAMAGLRAIGNPIADVVSPHPFAGWQQAFDPLLAPGARNY
                     WKSHDFMELSDQAIGVLTEAIRKLPGPECEIFIGHVGGAAGRVAAEETAFPQRSSHFV
                     MNVHGRWRDPDQDQVCIDWARHLFEAAKPYAAGTAYVNFMPEDEIDRVEAAYGANYGR
                     LVEIKRRYDPLNLFRMNQNVRPIQERGAA"
     misc_feature    914509..915831
                     /locus_tag="Smed_4422"
                     /note="FAD/FMN-containing dehydrogenases [Energy
                     production and conversion]; Region: GlcD; COG0277"
                     /db_xref="CDD:223354"
     misc_feature    914575..914982
                     /locus_tag="Smed_4422"
                     /note="FAD binding domain; Region: FAD_binding_4;
                     pfam01565"
                     /db_xref="CDD:216574"
     misc_feature    915691..915825
                     /locus_tag="Smed_4422"
                     /note="Berberine and berberine like; Region: BBE;
                     pfam08031"
                     /db_xref="CDD:219706"
     gene            915892..917313
                     /locus_tag="Smed_4423"
                     /db_xref="GeneID:5318987"
     CDS             915892..917313
                     /locus_tag="Smed_4423"
                     /note="PFAM: Pyridoxal-dependent decarboxylase;
                     KEGG: sme:SMb21414 putative amino acid decarboxylase,
                     pyridoxal-dependent protein"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="YP_001313159.1"
                     /db_xref="GI:150376563"
                     /db_xref="InterPro:IPR002129"
                     /db_xref="GeneID:5318987"
                     /translation="MEEVSARKIFQCAAGHAARFREKITELPQRPELSYPAALATFRE
                     ALPEQGSAGAEVIGDLAAKAEPGLHAMVGPRFFGWVIGGSHPVGVAADWMTSAWGQNA
                     GNHHAAPAAAAAEAVAANWLLDLLDLPRESSVGFATGATLANFICLAAARGEVLRQCG
                     WDVEAQGLFGAPPVSVLIGDDAHATVFSALQFLGFGHDRVVRVETDHTGRIAAPAFAG
                     AATKMTGPCIAIFQAGQINTGAFDDFSGIMPIARDIGAWVHVDGAFGLWARAAPSKRA
                     LTKSAEQAHSWATDGHKWLQTPYDCGYAIIRDQEAHRRAMTIAASYLPPSDEGERDPS
                     HFVPELSRRARGFATWAMIKHLGREGIAAMVDRHCRVARAIAERLTVEDGINVLNEVV
                     LNQVLVRFGAALPGEESDRLTQAAIARLQADGTCFAGGAVWRGRKVMRLSVISWLTDD
                     QAGEMTAEAIIATWRAVRGGTLV"
     misc_feature    915937..917301
                     /locus_tag="Smed_4423"
                     /note="Glutamate decarboxylase and related PLP-dependent
                     proteins [Amino acid transport and metabolism]; Region:
                     GadB; COG0076"
                     /db_xref="CDD:223154"
     misc_feature    order(916309..916314,916321..916323,916585..916587,
                     916672..916674,916681..916683,916759..916761,
                     916768..916770)
                     /locus_tag="Smed_4423"
                     /note="pyridoxal 5'-phosphate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:99742"
     misc_feature    916768..916770
                     /locus_tag="Smed_4423"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99742"
     gene            917452..917934
                     /locus_tag="Smed_4424"
                     /db_xref="GeneID:5318988"
     CDS             917452..917934
                     /locus_tag="Smed_4424"
                     /note="PFAM: Calcium-binding EF-hand-containing protein;
                     KEGG: sme:SMb21413 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding EF-hand-containing protein"
                     /protein_id="YP_001313160.1"
                     /db_xref="GI:150376564"
                     /db_xref="InterPro:IPR002048"
                     /db_xref="GeneID:5318988"
                     /translation="MSRMKFPAAAALAALMAIGTTSAAVAQAPAPVPPTGEMPATDQV
                     IEPDMPTGDEEGTGGAALQEQPDRMREDMIRGDGKRGDRMHGDRMRHRDRMGGAMMHR
                     QMMHRQMMKVMFAITDADNDGALSFEEISTIHKRIFDKVDINRDGKVTPDEIQGFFRN
                     "
     sig_peptide     917452..917532
                     /locus_tag="Smed_4424"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.917 at
                     residue 27"
     misc_feature    917782..917916
                     /locus_tag="Smed_4424"
                     /note="EF-hand, calcium binding motif; A diverse
                     superfamily of calcium sensors and calcium signal
                     modulators; most examples in this alignment model have 2
                     active canonical EF hands. Ca2+ binding induces a
                     conformational change in the EF-hand motif, leading to...;
                     Region: EFh; cl17302"
                     /db_xref="CDD:247856"
     misc_feature    order(917803..917805,917809..917811,917815..917817,
                     917836..917838,917875..917877,917881..917883,
                     917887..917889,917908..917910)
                     /locus_tag="Smed_4424"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238008"
     gene            918013..918384
                     /locus_tag="Smed_4425"
                     /db_xref="GeneID:5318138"
     CDS             918013..918384
                     /locus_tag="Smed_4425"
                     /note="PFAM: protein of unknown function DUF488;
                     KEGG: sme:SMb21412 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313161.1"
                     /db_xref="GI:150376565"
                     /db_xref="InterPro:IPR007438"
                     /db_xref="GeneID:5318138"
                     /translation="MASLLLKRVYEAPEASDGMRVLVDRLWPRGIAREKAEIDLWLKD
                     IAPSDALRKRFHGKPEDWAAFCANYAEELEGAAAQAAVVELGGLMARGPVTLLYAARD
                     EARNNAVALKAWLVRRGVEAS"
     misc_feature    918013..918366
                     /locus_tag="Smed_4425"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3189"
                     /db_xref="CDD:225730"
     gene            918727..919002
                     /locus_tag="Smed_4426"
                     /db_xref="GeneID:5318139"
     CDS             918727..919002
                     /locus_tag="Smed_4426"
                     /note="KEGG: rle:pRL120245 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313162.1"
                     /db_xref="GI:150376566"
                     /db_xref="GeneID:5318139"
                     /translation="MRDTAKTLNDMTPRERANLMTLVADALEATADEAQEIGDERFAA
                     NSISLARIISGCAEDVATMDLPAAELLLQHGISLIALFRDGARPVLH"
     gene            complement(919014..919835)
                     /locus_tag="Smed_4427"
                     /db_xref="GeneID:5318140"
     CDS             complement(919014..919835)
                     /locus_tag="Smed_4427"
                     /note="PFAM: UbiE/COQ5 methyltransferase;
                     Methyltransferase type 11; Methyltransferase type 12;
                     KEGG: sme:SMb21410 putative methyltransferase,
                     S-Adenosyl-L-methionine (SAM)-MTase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="type 11 methyltransferase"
                     /protein_id="YP_001313163.1"
                     /db_xref="GI:150376567"
                     /db_xref="InterPro:IPR004033"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="GeneID:5318140"
                     /translation="MTSSFNVHDAAGYEQLMGRWSRKLAPKFIDFAGIGDGERVLDVG
                     CGTGSLTFALAKAANLREIAAIDYSPVFVAEAARRNTDPRIKFEEADACALPFDDGSF
                     DRAFALLVLHFVPESGKAVAEMRRVVRSGGVVAAAVWDHLGGMPGMRMMVDTVAALSE
                     GGRQLRARYCFQPMVQPEEMKRAFAAQGLMDVAETQLMIRMDYRNFDDYWAPIAAGEG
                     PLGKYVAVLDAEERSRTEAAVRDAYEAGGPDGPRSFANVAWACRGTVPPTKVDPT"
     misc_feature    complement(919269..919787)
                     /locus_tag="Smed_4427"
                     /note="Methyltransferase domain; Region: Methyltransf_23;
                     pfam13489"
                     /db_xref="CDD:222171"
     misc_feature    complement(919467..919721)
                     /locus_tag="Smed_4427"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(919512..919514,919560..919568,
                     919632..919637,919689..919709))
                     /locus_tag="Smed_4427"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            920046..920297
                     /locus_tag="Smed_4428"
                     /pseudo
                     /db_xref="GeneID:5318141"
     gene            920296..920703
                     /locus_tag="Smed_4429"
                     /db_xref="GeneID:5318142"
     CDS             920296..920703
                     /locus_tag="Smed_4429"
                     /note="KEGG: reu:Reut_B5200 putative uncharacterized
                     protein conserved in bacteria putative lipoprotein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313164.1"
                     /db_xref="GI:150376568"
                     /db_xref="GeneID:5318142"
                     /translation="MARHFGFHRSWIEGRFTPSPDGARCASACASIVFIAGKTRTVED
                     RGSLGQHSCSRGGVPDEACNEAISRHAVKHGVSHGSIAAFVTYVAPESILWSSREDAE
                     GWGLTNYPTEDLSGFVRSEPRVLKVLTGEMPLA"
     misc_feature    <920353..>920499
                     /locus_tag="Smed_4429"
                     /note="Predicted periplasmic protein [Function unknown];
                     Region: COG3904"
                     /db_xref="CDD:226419"
     gene            920779..921045
                     /locus_tag="Smed_4430"
                     /db_xref="GeneID:5318143"
     CDS             920779..921045
                     /locus_tag="Smed_4430"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313165.1"
                     /db_xref="GI:150376569"
                     /db_xref="GeneID:5318143"
                     /translation="MQLNVFCSEKQPGRLFLGMEVNGPVGVVREVALRVAVETERTFW
                     ADAPIIHQKDSQISEIVTEVPTEQLKAFLTKTKRLAFGVAKKQP"
     gene            921327..921812
                     /locus_tag="Smed_4431"
                     /db_xref="GeneID:5318144"
     CDS             921327..921812
                     /locus_tag="Smed_4431"
                     /note="PFAM: 3-demethylubiquinone-9 3-methyltransferase;
                     KEGG: sme:SMb20475 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="3-demethylubiquinone-9 3-methyltransferase"
                     /protein_id="YP_001313166.1"
                     /db_xref="GI:150376570"
                     /db_xref="InterPro:IPR009725"
                     /db_xref="GeneID:5318144"
                     /translation="MSKNTICLWFDKDAEEAARFYAGTFPDSKVEAIIRAPGKYPDGE
                     EGDVLVVEFTVAGVACVGLNGGPTFKHNEAFSFQISTEDQDETDRYWNAIVGNGGQES
                     ECGWCKDKWGISWQITPRTLMEALQAGGEQAKRAFDAMMTMRKIDVAVIDAARRGDDA
                     R"
     misc_feature    921339..921680
                     /locus_tag="Smed_4431"
                     /note="Escherichia coli PhnB and similar proteins; the E.
                     coli phnB gene is found next to an operon involved in the
                     cleavage of carbon-phosphorus bonds in unactivated
                     alkylphosphonates; Region: PhnB_like; cd06588"
                     /db_xref="CDD:176658"
     misc_feature    order(921339..921353,921399..921401,921495..921500,
                     921507..921509,921549..921566,921570..921572,
                     921582..921584,921642..921644,921672..921674)
                     /locus_tag="Smed_4431"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:176658"
     gene            921809..922030
                     /locus_tag="Smed_4432"
                     /db_xref="GeneID:5318145"
     CDS             921809..922030
                     /locus_tag="Smed_4432"
                     /note="KEGG: sme:SMb20474 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313167.1"
                     /db_xref="GI:150376571"
                     /db_xref="GeneID:5318145"
                     /translation="MTTETIKGPASYFPSIEKKYGRPIDDWQELVRKRYPARHMELVG
                     MLKSEHGIGHGHANAIVAYTLAEDKQPAS"
     misc_feature    921830..922009
                     /locus_tag="Smed_4432"
                     /note="Domain of unknown function (DUF4287); Region:
                     DUF4287; pfam14117"
                     /db_xref="CDD:206286"
     gene            complement(922200..923093)
                     /locus_tag="Smed_4433"
                     /db_xref="GeneID:5318146"
     CDS             complement(922200..923093)
                     /locus_tag="Smed_4433"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMa1782 putative LysR-family transcriptional
                     regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001313168.1"
                     /db_xref="GI:150376572"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318146"
                     /translation="MTVSMEQLEAFVAAAEHGSFSAAGRALRKAQSAVSTQISTLEED
                     LGLELFSRRGRNPTLTSAGERLLSEAKLILDRREHLIGVAASFEAHVEKRLVVAIDEL
                     YPEHALGELFAEFAVQFPHVELELLFPMMEDVSRLVLDGKADIGVMWRQEDLPAELGF
                     HTIGWVQLNLVCAKSHPLANSVVDWEDLKRHRQIMVTVRTEGMERHRLRVAAEVWWVE
                     SHWVILQILKQGIGWALIPAHIIARSPVAQDLAIPALQFDDGAHPVALELVWHKQRPT
                     GPAATWLRKRFATTKIDIVAE"
     misc_feature    complement(922230..923084)
                     /locus_tag="Smed_4433"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    complement(922902..923081)
                     /locus_tag="Smed_4433"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    complement(922239..922814)
                     /locus_tag="Smed_4433"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cd05466"
                     /db_xref="CDD:176102"
     misc_feature    complement(order(922407..922412,922416..922421,
                     922434..922439,922452..922463,922710..922730,
                     922734..922736,922746..922748,922755..922760,
                     922764..922769))
                     /locus_tag="Smed_4433"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            923185..923625
                     /locus_tag="Smed_4434"
                     /db_xref="GeneID:5318147"
     CDS             923185..923625
                     /locus_tag="Smed_4434"
                     /note="PFAM: transmembrane pair domain protein;
                     KEGG: sme:SMa1780 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane pair domain-containing protein"
                     /protein_id="YP_001313169.1"
                     /db_xref="GI:150376573"
                     /db_xref="InterPro:IPR007896"
                     /db_xref="GeneID:5318147"
                     /translation="MKMRTFPDRIRHTLLFEVIGLMIVTPLAAYLFHKPIMHMGVVGI
                     GSATIATIWNFLFNLGFDHGMRRMFGSTTKTFRIRLVHTVLFEIGLLAILLPPIAWYL
                     NMGLLETLQLDLAIVAFYLVYNFVFNLAYDRVFPIPGAPRAEYA"
     misc_feature    923185..923622
                     /locus_tag="Smed_4434"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG4125"
                     /db_xref="CDD:226610"
     misc_feature    923194..923397
                     /locus_tag="Smed_4434"
                     /note="Bacterial Transmembrane Pair family; Region: BTP;
                     pfam05232"
                     /db_xref="CDD:218515"
     misc_feature    923404..923601
                     /locus_tag="Smed_4434"
                     /note="Bacterial Transmembrane Pair family; Region: BTP;
                     pfam05232"
                     /db_xref="CDD:218515"
     gene            complement(923662..924642)
                     /locus_tag="Smed_4435"
                     /db_xref="GeneID:5317957"
     CDS             complement(923662..924642)
                     /locus_tag="Smed_4435"
                     /note="KEGG: sme:SMb20513 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313170.1"
                     /db_xref="GI:150376574"
                     /db_xref="InterPro:IPR000209"
                     /db_xref="GeneID:5317957"
                     /translation="MKMPLLHCLATRFERRRFMQHFPYIGSGPYCYANAFAMMFGQHA
                     PSTAVIEFATGSPFGMQLVGGCLPFFDPFGWTPEAGFDAALDAMGWTSSVTSGGNAAD
                     AVERLRSELVHSPVWVGPVEMGWLRHQPGKDGPIGADHYVVVIGLANDWVQLHDPQGY
                     PFATLPIGDFLTAWQAETIDYGTPFTMRFGFRQMRVVDEDDEIRASLPAAIRWLSMQE
                     PRHMPEGTIGNGEAAEALASMIDAGCDEDLRAHLIHFAIRVGARRLADAATCLSRIDY
                     TDAAHIASEQAALTGALQYPLVAGNDAEAADLLRRLAPTYQRLLEALRLH"
     misc_feature    complement(923743..924564)
                     /locus_tag="Smed_4435"
                     /note="A predicted NlpC/p60-like peptidase; Region: BtrH;
                     pfam14399"
                     /db_xref="CDD:222736"
     gene            complement(924723..926021)
                     /locus_tag="Smed_4436"
                     /db_xref="GeneID:5317958"
     CDS             complement(924723..926021)
                     /locus_tag="Smed_4436"
                     /note="PFAM: MscS Mechanosensitive ion channel;
                     KEGG: sme:SMa1582 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel MscS"
                     /protein_id="YP_001313171.1"
                     /db_xref="GI:150376575"
                     /db_xref="InterPro:IPR006685"
                     /db_xref="GeneID:5317958"
                     /translation="MDFVQIFRPLEAWFRTFVLSEWTFYQLGIIAAGYIFASLVASIT
                     EPALETRARRIKGNPDLLRVIIAFMRRLKWLFLTIWLWLANVVLTQSTWPSQRWLVST
                     ALTLAAAWFVISVLTKIIRNQTLSRVVAVLSWGYLAVYATGLEGPALSTLDAAAVNLG
                     AMRLSLLIVLKAVVLTVALIWVAVLAGNVLSHWVQRSGDLSPSFKVLISKLIKIVLIM
                     VAGAIALSATGIDLTALTVFSGAVGVGVGFGLQKVVSNFISGIIILLDKSIKPGDTIT
                     LGDTFGSIRDLRARFVSVITREGKEFLIPNEDFISQQVVNWSFSSDYVRIDVDFGTSY
                     DSDPHEVVRIAIETASAVPRVANNYKAPVCWMTAFGASSLDFRLRFWISDPANGLTNV
                     RGQVLLALWDAFKAAKVSIPFPHREIIMKTPVEIQRPPRA"
     misc_feature    complement(924729..>926021)
                     /locus_tag="Smed_4436"
                     /note="Small-conductance mechanosensitive channel [Cell
                     envelope biogenesis, outer membrane]; Region: COG3264"
                     /db_xref="CDD:225803"
     misc_feature    complement(924789..925364)
                     /locus_tag="Smed_4436"
                     /note="Mechanosensitive ion channel; Region: MS_channel;
                     pfam00924"
                     /db_xref="CDD:201506"
     gene            complement(926176..926556)
                     /locus_tag="Smed_4437"
                     /db_xref="GeneID:5317959"
     CDS             complement(926176..926556)
                     /locus_tag="Smed_4437"
                     /note="PFAM: protein of unknown function DUF1486;
                     KEGG: sme:SMa1589 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313172.1"
                     /db_xref="GI:150376576"
                     /db_xref="InterPro:IPR009959"
                     /db_xref="GeneID:5317959"
                     /translation="MLHAFYRDYIDCLNRQDWDQLGRYVAGDVRHNGRLLGLSGYRSM
                     LVKDFEDIPDLLFKIDRLACEPPLIAARLKFDCSPKGSFLGLAINGRRISFAENVFYE
                     VTNGKIADVFSVIDKTAIEDQIGK"
     misc_feature    complement(926182..926541)
                     /locus_tag="Smed_4437"
                     /note="Nuclear transport factor 2 (NTF2-like) superfamily.
                     This family includes members of the NTF2 family,
                     Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases,
                     and the beta subunit of Ring hydroxylating dioxygenases.
                     This family is a classic example of...; Region: NTF2_like;
                     cl09109"
                     /db_xref="CDD:245009"
     gene            complement(927056..927502)
                     /locus_tag="Smed_4438"
                     /db_xref="GeneID:5317960"
     CDS             complement(927056..927502)
                     /locus_tag="Smed_4438"
                     /note="KEGG: sme:SMb21030 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313173.1"
                     /db_xref="GI:150376577"
                     /db_xref="GeneID:5317960"
                     /translation="MLRKSLLAIFVASATVAATPAAAQECDAAGTIGSGGSAAAGGTS
                     ASTVGTAGTCRTDSGTTSSIGAGGSAATSDEKAKSRTKINENPSQLQGQSKAQAMDKG
                     TFSKSQTKTKVTEDGLQSRTKTMSHVPGEKPTQSKTKTILPLPQQQ"
     sig_peptide     complement(927431..927502)
                     /locus_tag="Smed_4438"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.965 at
                     residue 24"
     gene            927566..927946
                     /locus_tag="Smed_4439"
                     /db_xref="GeneID:5317961"
     CDS             927566..927946
                     /locus_tag="Smed_4439"
                     /note="KEGG: rle:RL1066 putative transmembrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313174.1"
                     /db_xref="GI:150376578"
                     /db_xref="GeneID:5317961"
                     /translation="MPSGRVTLAVAKLSPSEDPLVAEDPALLVADPPLAAAPPPTVVD
                     EDTLPEPTVTDDETPPPSDDSCSMIMQVEPSSSLISFAPAWSGTAIMAADRAVTTGIM
                     NELEVIGSPPIWKTLASGAPKPAD"
     gene            complement(927949..928488)
                     /locus_tag="Smed_4440"
                     /db_xref="GeneID:5317962"
     CDS             complement(927949..928488)
                     /locus_tag="Smed_4440"
                     /note="KEGG: rle:RL1067 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313175.1"
                     /db_xref="GI:150376579"
                     /db_xref="GeneID:5317962"
                     /translation="MRFFIKTALAAGLLAGTTLGAFAQSSTTIGTGGTSAGGGTSSST
                     VGTGGSSAGGNCDPGTSDCQSGSASTLGTGGSSAGGGTSSSSVGTGGSAAGSGSGGSA
                     STIGTGGSSAGGGSSSSSVGTGGSAAGSADGPSDETTGSVQGDENSARDAAQDDESNK
                     NCPPGLAKKDGSTGDRPSC"
     sig_peptide     complement(928417..928488)
                     /locus_tag="Smed_4440"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.987 at
                     residue 24"
     gene            complement(928693..929424)
                     /locus_tag="Smed_4441"
                     /db_xref="GeneID:5317963"
     CDS             complement(928693..929424)
                     /locus_tag="Smed_4441"
                     /note="KEGG: rle:RL0486 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313176.1"
                     /db_xref="GI:150376580"
                     /db_xref="GeneID:5317963"
                     /translation="MSAARSQGGTGLRQFLDLQQQRDWIDGKTILPDAEERSQSMELR
                     FKYAARFEKLLRRQQAPEVLEVLRRYGRDCIPIPHRTERHYWSVSCLPSTPGKALVRI
                     NASWMELFSLYADGEGIRALFLVHLSDFTTDHSLDHGQVDDAFIERCVVTPEDVSYFF
                     PPGEDIFGIKARGFSSICKFIAQSRALRAIRTFNLTHMNRGRNAFQASHCYSLADHML
                     SDGNAEERQSHAARGGSRMKKSPRE"
     gene            complement(929421..929999)
                     /locus_tag="Smed_4442"
                     /db_xref="GeneID:5317964"
     CDS             complement(929421..929999)
                     /locus_tag="Smed_4442"
                     /note="PFAM: regulatory protein TetR;
                     KEGG: sco:SCO4454 transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_001313177.1"
                     /db_xref="GI:150376581"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="GeneID:5317964"
                     /translation="MRQKKSENQPEASSARRRLLDAATRLFYEGGIHAVGIDRIIAEA
                     GVAKATFYNHFPSKDDLVVAYLEEIDRLGRAAVAALPKQPPRKAISAIMGRISEAVTA
                     GGWRGCPFLNAAAEYPDPASPVRQAIDARRAWYHDSLENLLAEDGDPAPSVTASLLVA
                     LSDGLLESAYLDGAESVPALVREAVARLLDRR"
     misc_feature    complement(929430..929921)
                     /locus_tag="Smed_4442"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    complement(929808..929921)
                     /locus_tag="Smed_4442"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:201228"
     gene            930097..930495
                     /locus_tag="Smed_4443"
                     /db_xref="GeneID:5317965"
     CDS             930097..930495
                     /locus_tag="Smed_4443"
                     /note="PFAM: protein of unknown function DUF1486;
                     KEGG: mlo:mll8193 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313178.1"
                     /db_xref="GI:150376582"
                     /db_xref="InterPro:IPR009959"
                     /db_xref="GeneID:5317965"
                     /translation="MTAAISLKEVRKISESNVTREIVERFNNAFEKHRPEDLDDLFGE
                     NCVLENTAPAPDGARYEGREACLAFWKGIASSADLVFKAEDISVMGDRGIIRWQLRWS
                     EREADRIRGVNLMRVRDGKIIEGLGYVKGG"
     misc_feature    930163..930468
                     /locus_tag="Smed_4443"
                     /note="SnoaL-like domain; Region: SnoaL_2; pfam12680"
                     /db_xref="CDD:221707"
     gene            complement(930581..931090)
                     /locus_tag="Smed_4444"
                     /db_xref="GeneID:5317966"
     CDS             complement(930581..931090)
                     /locus_tag="Smed_4444"
                     /note="KEGG: ret:RHE_PE00376 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313179.1"
                     /db_xref="GI:150376583"
                     /db_xref="GeneID:5317966"
                     /translation="MRARWVVVNDRMQQGYRYALVAPIGRDFHADFRPDLTPAEMLAL
                     GVFGGKYMTDCRDEFPNSWFVGARLSSLRKDPSINCFGVDASQPLSVWRAKGWIHPED
                     PRGWFQWYCRYHQGRRMPGEDERQIARWKALRRHIAQLRRACEPGDCWCRPRQRQALL
                     HWAYDSRSI"
     gene            complement(931087..931575)
                     /locus_tag="Smed_4445"
                     /db_xref="GeneID:5317967"
     CDS             complement(931087..931575)
                     /locus_tag="Smed_4445"
                     /note="PFAM: TspO/MBR family protein;
                     KEGG: sme:SMa1079 TspO tryptophan rich sensory protein
                     homologue"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO and MBR like protein"
                     /protein_id="YP_001313180.1"
                     /db_xref="GI:150376584"
                     /db_xref="InterPro:IPR004307"
                     /db_xref="GeneID:5317967"
                     /translation="MHSLLVLVAFEVASFAAAATGVIFRPGDWYKQLNKPRWRPPNWL
                     FAPVWAVLYASIGLSGWLVWQEAGIAGAALPLGVYAVQLLLNAAWTPIFFGLHRPGLA
                     AVEIMVLWAAILATTVMFHPVNAAAALLLVPYLAWVSFAAALNLSIWRRNPSKTLSQS
                     AR"
     sig_peptide     complement(931519..931575)
                     /locus_tag="Smed_4445"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.856) with cleavage site probability 0.558 at
                     residue 19"
     misc_feature    complement(931126..931503)
                     /locus_tag="Smed_4445"
                     /note="TspO/MBR family; Region: TspO_MBR; pfam03073"
                     /db_xref="CDD:217354"
     gene            complement(931636..931860)
                     /locus_tag="Smed_4446"
                     /db_xref="GeneID:5318598"
     CDS             complement(931636..931860)
                     /locus_tag="Smed_4446"
                     /note="PFAM: protein of unknown function DUF378;
                     KEGG: sme:SMa1078 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313181.1"
                     /db_xref="GI:150376585"
                     /db_xref="InterPro:IPR007211"
                     /db_xref="GeneID:5318598"
                     /translation="MNFINIFTLILVIVGGLNWGLVGLLGFDLVAAIFGAGSGLARIV
                     YILVGLSAAWQIIPLFSVMGSGAFAANQNR"
     misc_feature    complement(931663..931860)
                     /locus_tag="Smed_4446"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG2155"
                     /db_xref="CDD:225066"
     gene            complement(931889..932371)
                     /locus_tag="Smed_4447"
                     /db_xref="GeneID:5318599"
     CDS             complement(931889..932371)
                     /locus_tag="Smed_4447"
                     /note="PFAM: beta-Ig-H3/fasciclin;
                     KEGG: sme:SMa1077 Nex18 symbiotically induced conserved
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-Ig-H3/fasciclin"
                     /protein_id="YP_001313182.1"
                     /db_xref="GI:150376586"
                     /db_xref="InterPro:IPR000782"
                     /db_xref="GeneID:5318599"
                     /translation="MKLNSLLFAAAITLGSVSAFAADKDVVDTAMEAGQFKTLGAALE
                     AAGLVATLKETGPFTVFAPTDEAFAKLPAGTVENLLKPENKQKLAEILTYHVVAGKVM
                     ASDVAGIDEAKSVNGKMIDIEVEGSNVKVNDAAVTAADIAASNGVIHVIDKVIMPPEG
                     "
     misc_feature    complement(931892..932371)
                     /locus_tag="Smed_4447"
                     /note="Secreted and surface protein containing
                     fasciclin-like repeats [Cell envelope biogenesis, outer
                     membrane]; Region: COG2335"
                     /db_xref="CDD:225214"
     sig_peptide     complement(932306..932371)
                     /locus_tag="Smed_4447"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 22"
     misc_feature    complement(931901..932206)
                     /locus_tag="Smed_4447"
                     /note="Fasciclin domain; Region: Fasciclin; pfam02469"
                     /db_xref="CDD:217054"
     gene            932533..933114
                     /locus_tag="Smed_4448"
                     /db_xref="GeneID:5318600"
     CDS             932533..933114
                     /locus_tag="Smed_4448"
                     /note="PFAM: helix-turn-helix domain protein; Cupin 2
                     conserved barrel domain protein;
                     KEGG: ret:RHE_PE00372 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="YP_001313183.1"
                     /db_xref="GI:150376587"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="GeneID:5318600"
                     /translation="MLSDTLSNELQRYAIGPRIKALRLRKKLGLVQLAGHTGLSPAML
                     SKIERGQMFPTLPTLLRIAMVFGVGLDHFFNVDKEEPLIAIVRKEQRLKLPSPPGEKH
                     PAFLFESLDYPASDRRMDAFYAEFPVDSPPSEPHQHGSAEFIYVLSGRLIVNVNGKEC
                     ALDTGDAVYFDSSVPHSYRHEGKEISTAIVVTS"
     misc_feature    932575..932901
                     /locus_tag="Smed_4448"
                     /note="Predicted transcriptional regulators
                     [Transcription]; Region: HipB; COG1396"
                     /db_xref="CDD:224314"
     misc_feature    932578..932751
                     /locus_tag="Smed_4448"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; Region: HTH_XRE; cd00093"
                     /db_xref="CDD:238045"
     misc_feature    order(932590..932592,932602..932604,932677..932679)
                     /locus_tag="Smed_4448"
                     /note="non-specific DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238045"
     misc_feature    order(932599..932601,932674..932676)
                     /locus_tag="Smed_4448"
                     /note="salt bridge; other site"
                     /db_xref="CDD:238045"
     misc_feature    order(932620..932625,932656..932658,932665..932667,
                     932677..932682)
                     /locus_tag="Smed_4448"
                     /note="sequence-specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238045"
     misc_feature    932929..933105
                     /locus_tag="Smed_4448"
                     /note="Cupin domain; Region: Cupin_2; pfam07883"
                     /db_xref="CDD:219618"
     gene            complement(933217..933840)
                     /locus_tag="Smed_4449"
                     /db_xref="GeneID:5318601"
     CDS             complement(933217..933840)
                     /locus_tag="Smed_4449"
                     /note="KEGG: sme:SMc01547 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313184.1"
                     /db_xref="GI:150376588"
                     /db_xref="GeneID:5318601"
                     /translation="MAKHKQYVDSELIKTWSLPTSVTLGSAVRAKGILQEIRARLPLA
                     VRKALVLESAVLTMSMPDTSRAIFRATSASVTGMLSDMESLPVIPREIEDILAISTSE
                     RRRWLQDGRLPSAGTRTVKLRGRARQITFHVFDPAVVMDILDRGAVDEWREYDIVAVA
                     EKRRQSAMKAKLTRSLRKKKDKPAPKDGSTSSPLRGWDEFDADGFLK"
     gene            complement(934104..934997)
                     /locus_tag="Smed_4450"
                     /db_xref="GeneID:5318602"
     CDS             complement(934104..934997)
                     /locus_tag="Smed_4450"
                     /EC_number="4.2.1.1"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: bja:bll6530 transcriptional regulatory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001313185.1"
                     /db_xref="GI:150376589"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318602"
                     /translation="MQREDMKDLLWFLEVAREQSFTKAAAALGTSQSTLSYTIKQLEA
                     RLGVRLLTRTTRSVATTEAGERLFQSLAPRFQQIEADLAALVAFREKPSGTVRLTLSD
                     HALQTTVWPKLSRVLSDYPDIRLELYSDNGMSNIVEERFDAGVRLGESVDKDMIAVRI
                     SPDWRLRAVASPEYFTKHGIPTTPQDLVGHVCINMRQATWGGFYSWEFEKDGRELRVR
                     VDGQLSFNSSITQVEAALEGYGIAYVPENLVEEHLAVGRLRAVLDDWSQPFTGYHLYY
                     PSRRQMSPAMTVIVEALRHRS"
     misc_feature    complement(934110..934985)
                     /locus_tag="Smed_4450"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    complement(934803..934982)
                     /locus_tag="Smed_4450"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    complement(934119..934724)
                     /locus_tag="Smed_4450"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     Region: PBP2_CrgA_like_5; cd08474"
                     /db_xref="CDD:176163"
     misc_feature    complement(order(934182..934184,934263..934265,
                     934314..934316,934506..934508,934515..934517,
                     934557..934559,934674..934676,934686..934688))
                     /locus_tag="Smed_4450"
                     /note="putative effector binding pocket; other site"
                     /db_xref="CDD:176163"
     misc_feature    complement(order(934287..934289,934296..934301,
                     934320..934334,934425..934427,934611..934631,
                     934635..934637,934647..934649,934656..934661,
                     934665..934670,934680..934685))
                     /locus_tag="Smed_4450"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176163"
     gene            935103..936311
                     /locus_tag="Smed_4451"
                     /db_xref="GeneID:5318603"
     CDS             935103..936311
                     /locus_tag="Smed_4451"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: rle:pRL110158 putative transcription regulatory
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001313186.1"
                     /db_xref="GI:150376590"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5318603"
                     /translation="MPIGTDTMTLTYNENIHSRPRAWGAVFSMTLCVFVLIASEFMPV
                     SLLTPIAADLGVSEGSAGQAISISGIFAVFTSLFIAALTRRLDRRVVVLALTFLLMLS
                     GVAVTFAPSYPMLMLGRALLGISIGGFWSMSTSIVMRLVSRDQVPKALALLNAGNAIA
                     ATISAPLGSLLGSYIGWRGAFFLVVPVGLLALIWQWISLPTLSPRRDGASRNVLRLLA
                     RPPVALGMAAILLLFMGQFAFFTYLRPFLEQVTHLGIETLSLMLLVMGLSGVAGTSLV
                     GRLLTHRLFSILIVIPFLMACIALAMIGIGEMRTPVVMSLIGWGFLGTAAPVAWGTWL
                     SRVLADDAEAGGGLQVAVIQLAITAGASLGGLLFDALGWWSTFSLSALLLFGSSLASF
                     AAWLSARRAS"
     misc_feature    935139..936218
                     /locus_tag="Smed_4451"
                     /note="ribonucleoside transporter; Reviewed; Region: nepI;
                     PRK10213"
                     /db_xref="CDD:182309"
     misc_feature    935178..936218
                     /locus_tag="Smed_4451"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    order(935220..935222,935229..935237,935241..935246,
                     935295..935297,935304..935309,935316..935318,
                     935328..935333,935337..935342,935478..935483,
                     935490..935495,935502..935507,935514..935516,
                     935550..935555,935562..935567,935583..935585,
                     935799..935801,935808..935813,935820..935825,
                     935832..935834,935874..935876,935886..935888,
                     935898..935900,935907..935909,935919..935921,
                     936060..936062,936069..936074,936081..936083,
                     936093..936098,936105..936107,936135..936140,
                     936147..936152,936159..936164,936171..936173)
                     /locus_tag="Smed_4451"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            936403..937482
                     /locus_tag="Smed_4452"
                     /db_xref="GeneID:5318604"
     CDS             936403..937482
                     /locus_tag="Smed_4452"
                     /note="KEGG: rle:pRL110145 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313187.1"
                     /db_xref="GI:150376591"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5318604"
                     /translation="MSEHVDTDDVCNTSRRNLMKGTGLAVAAISMIPAVTATGAFAQS
                     PAWDKVFPKSENVDHQKVSFKNRYGITIAGDLYLPKNRGSQPLAALAVAGPFGAVKEQ
                     SSGLYAQTMAERGFAALAFDPSFTGESGGEPRNVASPDINTEDFSAAVDYLGLQPTID
                     RERIGVIGICGWGGMALNAVAADKRVKAVVASTMYDMTRLMSKGYNDSVTQEQRTQTL
                     EQLSRQRWADAEKNGPAYQPPYNVLKGGEAQFLVDYHDYYMTPRGYHPRAVNSGNAWT
                     QTTPLSFMNMPILTYIAEISPRPLLLIHGENAHSRYFSETAFAAAAEPKELMIIPNAN
                     HTDLYDRMDKIPFDRIAKFFGQHLA"
     sig_peptide     936403..936531
                     /locus_tag="Smed_4452"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.758) with cleavage site probability 0.748 at
                     residue 43"
     misc_feature    936541..937479
                     /locus_tag="Smed_4452"
                     /note="Hydrolases of the alpha/beta superfamily [General
                     function prediction only]; Region: COG1073"
                     /db_xref="CDD:223999"
     misc_feature    936724..>937008
                     /locus_tag="Smed_4452"
                     /note="Prolyl oligopeptidase family; Region: Peptidase_S9;
                     pfam00326"
                     /db_xref="CDD:215859"
     gene            937679..938869
                     /locus_tag="Smed_4453"
                     /db_xref="GeneID:5318605"
     CDS             937679..938869
                     /locus_tag="Smed_4453"
                     /note="PFAM: Carboxymuconolactone decarboxylase; Cupin 2
                     conserved barrel domain protein;
                     KEGG: bxe:Bxe_B1954 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase"
                     /protein_id="YP_001313188.1"
                     /db_xref="GI:150376592"
                     /db_xref="InterPro:IPR003779"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="GeneID:5318605"
                     /translation="MKYIAASIAISALAATAVEAQEERRKIAPPAVYDVAPGLGHFTD
                     DVLFGEVWERTELPSRDRSLVTLSAIVSTGKTAQIGAHVSRALDNGVKPGEIGELITH
                     LAFYSGWPNAISAVTETKKVFDERQIAPVKNSEAARIELEAAAEAARSETVSTTVAPT
                     AAALADLTNRVLFGDLWQRPDLSARDRSLVTIAALIAVGQPEQLPFHANRAMDSGLTP
                     SEASEVLAHVAFYAGWPRAMSAVPVLKQVLNNRQGTQVSASQADLKITPAGIGSASAP
                     EEYFTGTVQISGRYQADAPARIGGATVSFSAGARTAWHTHPLGQTLFIVSGRGLVQKE
                     GEAVQEVGSGDVVWIPPLIRHWHGASSTGPMTHFAVAEALDGSSVTWMEKVSDEDYGK
                     GVRE"
     sig_peptide     937679..937741
                     /locus_tag="Smed_4453"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.924 at
                     residue 21"
     misc_feature    <937799..938062
                     /locus_tag="Smed_4453"
                     /note="Uncharacterized homolog of
                     gamma-carboxymuconolactone decarboxylase subunit [Function
                     unknown]; Region: COG0599"
                     /db_xref="CDD:223672"
     misc_feature    <938189..938443
                     /locus_tag="Smed_4453"
                     /note="Uncharacterized homolog of
                     gamma-carboxymuconolactone decarboxylase subunit [Function
                     unknown]; Region: COG0599"
                     /db_xref="CDD:223672"
     misc_feature    938504..938836
                     /locus_tag="Smed_4453"
                     /note="Uncharacterized conserved protein, contains
                     double-stranded beta-helix domain [Function unknown];
                     Region: COG1917"
                     /db_xref="CDD:224829"
     gene            938979..939389
                     /locus_tag="Smed_4454"
                     /db_xref="GeneID:5318606"
     CDS             938979..939389
                     /locus_tag="Smed_4454"
                     /note="KEGG: tde:TDE0356 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313189.1"
                     /db_xref="GI:150376593"
                     /db_xref="InterPro:IPR000971"
                     /db_xref="GeneID:5318606"
                     /translation="MLKTMLGSAVIALGVVGPVMPQERIRISSAWGEVTADLADNEAA
                     KSLAQMLPLTIDMSDHFRQEKTGNLPSSLPELPRQRDFSVGTLGLWSSDHFVIYYRTG
                     RVPSPGIIVLGKVAGDVSIFDRPGSVTVTLEAVD"
     misc_feature    <939039..939383
                     /locus_tag="Smed_4454"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG4925"
                     /db_xref="CDD:227262"
     gene            complement(939471..939657)
                     /locus_tag="Smed_4455"
                     /pseudo
                     /db_xref="GeneID:5318607"
     gene            939773..940009
                     /locus_tag="Smed_4456"
                     /db_xref="GeneID:5317926"
     CDS             939773..940009
                     /locus_tag="Smed_4456"
                     /note="KEGG: sme:SMc01546 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313190.1"
                     /db_xref="GI:150376594"
                     /db_xref="GeneID:5317926"
                     /translation="MVSEPTVADAINRIYESLQADNADIDTHIATLKAALTREGLKEA
                     VFDPARLVQNNRSGRKLMQAYFRQRGVTVKYSAS"
     gene            940103..940462
                     /locus_tag="Smed_4457"
                     /db_xref="GeneID:5317927"
     CDS             940103..940462
                     /locus_tag="Smed_4457"
                     /note="KEGG: rle:RL1210 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313191.1"
                     /db_xref="GI:150376595"
                     /db_xref="GeneID:5317927"
                     /translation="MPKAVGIGGLFFRAANPAGLAEWYQKHLGIDDLHKSVWRQEAGM
                     TIFGPFSKDTDYFGRAEQQWMVNFRVDDLDGLVASLTASGIAVETRNEWNSEVGRFAR
                     IHDPEGNPVELWEPAQD"
     misc_feature    940130..940441
                     /locus_tag="Smed_4457"
                     /note="This domain superfamily is found in a variety of
                     structurally related metalloproteins, including the type I
                     extradiol dioxygenases, glyoxalase I and a group of
                     antibiotic resistance proteins; Region: Glo_EDI_BRP_like;
                     cd06587"
                     /db_xref="CDD:211348"
     misc_feature    order(940139..940141,940244..940246,940250..940252,
                     940295..940297,940406..940408,940430..940432,
                     940436..940438)
                     /locus_tag="Smed_4457"
                     /note="active site"
                     /db_xref="CDD:211348"
     gene            940735..940944
                     /locus_tag="Smed_4458"
                     /db_xref="GeneID:5317928"
     CDS             940735..940944
                     /locus_tag="Smed_4458"
                     /note="PFAM: Cold-shock protein DNA-binding;
                     SMART: Cold shock protein;
                     KEGG: rle:pRL110542 putative cold shock protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock DNA-binding domain-containing
                     protein"
                     /protein_id="YP_001313192.1"
                     /db_xref="GI:150376596"
                     /db_xref="InterPro:IPR002059"
                     /db_xref="InterPro:IPR011129"
                     /db_xref="GeneID:5317928"
                     /translation="MTTGTVKWFNSTKGFGFIEPDNGGADAFVHISAVERAGMREIVE
                     GQKLSYELERDNKSGKMSACNLQAA"
     misc_feature    940741..940905
                     /locus_tag="Smed_4458"
                     /note="Cold-Shock Protein (CSP) contains an S1-like
                     cold-shock domain (CSD) that is found in eukaryotes,
                     prokaryotes, and archaea.  CSP&apos;s include the major
                     cold-shock proteins CspA and CspB in bacteria and the
                     eukaryotic gene regulatory factor Y-box...; Region:
                     CSP_CDS; cd04458"
                     /db_xref="CDD:239905"
     misc_feature    order(940756..940758,940783..940785,940816..940818,
                     940903..940905)
                     /locus_tag="Smed_4458"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:239905"
     misc_feature    order(940774..940794,940813..940824)
                     /locus_tag="Smed_4458"
                     /note="RNA-binding motif; other site"
                     /db_xref="CDD:239905"
     gene            941073..941297
                     /locus_tag="Smed_4459"
                     /db_xref="GeneID:5317929"
     CDS             941073..941297
                     /locus_tag="Smed_4459"
                     /note="KEGG: ret:RHE_CH00434 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313193.1"
                     /db_xref="GI:150376597"
                     /db_xref="GeneID:5317929"
                     /translation="MAQTFSKTRQRAESAFNKVQSQFFARGQAVEEQDFVAQARDAKT
                     ARLREARLAKESDDRARATSTLITRRAKPA"
     gene            941347..941643
                     /locus_tag="Smed_4460"
                     /db_xref="GeneID:5317930"
     CDS             941347..941643
                     /locus_tag="Smed_4460"
                     /note="KEGG: atc:AGR_pAT_759 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313194.1"
                     /db_xref="GI:150376598"
                     /db_xref="GeneID:5317930"
                     /translation="MADDRLELQASTTAWQIAMQEILRMVVRDLYQSHGEVAFTAHIK
                     RLEEGAVDSIYSDLRLRGTNEWTETLVKEKATNIVTNLLTSFTFEQSDPRPRTA"
     gene            942197..942637
                     /locus_tag="Smed_4461"
                     /db_xref="GeneID:5317931"
     CDS             942197..942637
                     /locus_tag="Smed_4461"
                     /note="KEGG: sme:SMc00281 hypothetical signal peptide
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative signal peptide protein"
                     /protein_id="YP_001313195.1"
                     /db_xref="GI:150376599"
                     /db_xref="GeneID:5317931"
                     /translation="MARLLTAIFVAFGICLFSLASAKADPGDEVKAAYSAWDAAFNNA
                     DAKAIAAFYTDDAIFLPATHDVIRGPSGVEKFFGGIFGMGVTGHKLELIEAQGEGNLL
                     ISTAKWSAKGKDAKGADQPWAGVATHMFEKQADGGLKLRVHTFN"
     sig_peptide     942197..942265
                     /locus_tag="Smed_4461"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.433 at
                     residue 23"
     misc_feature    942251..942625
                     /locus_tag="Smed_4461"
                     /note="Ketosteroid isomerase homolog [Function unknown];
                     Region: COG4319"
                     /db_xref="CDD:226769"
     gene            943475..943852
                     /locus_tag="Smed_4462"
                     /db_xref="GeneID:5317932"
     CDS             943475..943852
                     /locus_tag="Smed_4462"
                     /note="PFAM: helix-turn-helix domain protein;
                     KEGG: noc:Noc_2930 transcriptional regulator, XRE family"
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="YP_001313196.1"
                     /db_xref="GI:150376600"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="GeneID:5317932"
                     /translation="MRLPYVHLNEQKVTKLPRTRSYSRVTRQALTMLGKLIRIGRAER
                     GLTAQELADRAGISRTTLSSIEKGAPGPEIGIVFEVASLVGVRLFDYDERTLQMQNAR
                     LDEKLTLLPKSVRHAVKEVDDDF"
     misc_feature    943568..>943804
                     /locus_tag="Smed_4462"
                     /note="Predicted transcriptional regulators
                     [Transcription]; Region: HipB; COG1396"
                     /db_xref="CDD:224314"
     misc_feature    943574..943738
                     /locus_tag="Smed_4462"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; Region: HTH_XRE; cd00093"
                     /db_xref="CDD:238045"
     misc_feature    order(943586..943588,943598..943600,943673..943675)
                     /locus_tag="Smed_4462"
                     /note="non-specific DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238045"
     misc_feature    order(943595..943597,943670..943672)
                     /locus_tag="Smed_4462"
                     /note="salt bridge; other site"
                     /db_xref="CDD:238045"
     misc_feature    order(943616..943621,943652..943654,943661..943663,
                     943673..943678)
                     /locus_tag="Smed_4462"
                     /note="sequence-specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238045"
     gene            943842..945164
                     /locus_tag="Smed_4463"
                     /db_xref="GeneID:5317933"
     CDS             943842..945164
                     /locus_tag="Smed_4463"
                     /note="PFAM: HipA domain protein;
                     KEGG: ppd:Ppro_0263 HipA domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="HipA domain-containing protein"
                     /protein_id="YP_001313197.1"
                     /db_xref="GI:150376601"
                     /db_xref="InterPro:IPR012893"
                     /db_xref="InterPro:IPR012894"
                     /db_xref="GeneID:5317933"
                     /translation="MTSKADATEAFVWIWLPGATEPVVAGRLFQEGERLLFNYGASYR
                     GRKTAIPIYEPELPLQEGAIAPINGLQMASCIRDGSPDAWGRRVIINRLTGKKPDADG
                     VPEISELTYLLHSGSDRTGALDFQASATEYVPRRAAQASLDELMEAAALVEKGVPLTP
                     ALAQALNHGTSIGGARPKALINDDTKKFIAKFSASNDTYSVVKAEFIAMRLASASGLD
                     VASVSITRAAHKDVLLIERFDRRHTKEGWTRQAMVSALTILGLDEMMARYASYEDLAE
                     LIRHRFTAPKDTLKELYGRICFNVLCGNTDDHARNHAAFWDGKMMTLTPAYDICPQSR
                     TGTEATQAMLIKGEGRASTLANCLAAAPDYHLKEADATALIEHQITTIAEQWQAVCAE
                     AELTPVDRQFFAGRQFLNNYAIEGLEGHKALHDAFGAARKALIASGDA"
     misc_feature    943881..944216
                     /locus_tag="Smed_4463"
                     /note="HipA N-terminal domain; Region: Couple_hipA;
                     cl11853"
                     /db_xref="CDD:245787"
     misc_feature    944352..944561
                     /locus_tag="Smed_4463"
                     /note="HipA-like N-terminal domain; Region: HipA_N;
                     pfam07805"
                     /db_xref="CDD:219588"
     misc_feature    944586..944825
                     /locus_tag="Smed_4463"
                     /note="HipA-like C-terminal domain; Region: HipA_C;
                     pfam07804"
                     /db_xref="CDD:219587"
     gene            945180..945374
                     /locus_tag="Smed_4464"
                     /pseudo
                     /db_xref="GeneID:5317934"
     gene            complement(945375..945451)
                     /locus_tag="Smed_R0064"
                     /note="tRNA-Arg4"
                     /db_xref="GeneID:5317935"
     tRNA            complement(945375..945451)
                     /locus_tag="Smed_R0064"
                     /product="tRNA-Arg"
                     /db_xref="GeneID:5317935"
     gene            complement(945633..946418)
                     /locus_tag="Smed_4465"
                     /db_xref="GeneID:5317936"
     CDS             complement(945633..946418)
                     /locus_tag="Smed_4465"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20904 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313198.1"
                     /db_xref="GI:150376602"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5317936"
                     /translation="MTEQRTPLVEMKNISISFGGIHAVDNASVDLYPGEVVALLGHNG
                     AGKSTLIKILSGAYRRDAGEILINGEPAEIGNPRDAKKYGIETIYQTLAVADNVDAAA
                     NLYLGRELRTPWGTLDDVAMEAKAREVMGRLNPNFQRFKEPVKALSGGQRQSVAIARA
                     ILFDARILIMDEPTAALGPQETAQVGELIKQLKREGIGIFLISHDIHDVFDLADRVSV
                     MKNGQVVGHARTEDVTKDEVLGMIIMGKVPPKAIPGPGAMQMA"
     misc_feature    complement(945708..946403)
                     /locus_tag="Smed_4465"
                     /note="ABC-type branched-chain amino acid transport
                     systems, ATPase component [Amino acid transport and
                     metabolism]; Region: LivG; COG0411"
                     /db_xref="CDD:223488"
     misc_feature    complement(945738..946394)
                     /locus_tag="Smed_4465"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    complement(946275..946298)
                     /locus_tag="Smed_4465"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(945807..945809,945903..945908,
                     946149..946151,946272..946280,946284..946289))
                     /locus_tag="Smed_4465"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(946149..946160)
                     /locus_tag="Smed_4465"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(945993..946022)
                     /locus_tag="Smed_4465"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(945903..945920)
                     /locus_tag="Smed_4465"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(945885..945896)
                     /locus_tag="Smed_4465"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(945801..945821)
                     /locus_tag="Smed_4465"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     gene            complement(946433..947767)
                     /locus_tag="Smed_4466"
                     /db_xref="GeneID:5318168"
     CDS             complement(946433..947767)
                     /locus_tag="Smed_4466"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20903 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inner-membrane translocator"
                     /protein_id="YP_001313199.1"
                     /db_xref="GI:150376603"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318168"
                     /translation="MSMADITQANQTQGTQTSRARKANENLVKRFFRATEIDTRLLGM
                     VGALIIIWLGFQVMTGGLFLTPRNLWNLTVQTSSVAVMATGMVLVIVTRNIDLSVGSV
                     LGFCGMIMGVLQAQVLPQYLGLGHPAIWAITLACGIAVGAAIGALHGSIIAFLNVPSF
                     IVTLGGLLVWRGATWFVTSGQTVAPMDTTFRLMGGGTQGSIGATASWVVGVLACIAII
                     GAVLNSRRQRKRFGFPLRPVWAEYFLTILGCALVLGAVSVANHYYWPINIARRYADAN
                     SIAWPDGGLQIPHGIAVPVLVAIVVGIVMTFIATRLRFGRYVFALGGNPEAAELAGIK
                     TRWVTVKIFMLMGVLCAIAAAISTARLNAATNAQGELDELYTIAAAVIGGTSLAGGVG
                     TIAGAMIGALVMQSLQSGMVLLGIDTPFQRIVVGVVLVTAVWLDTVYRARAK"
     misc_feature    complement(<947114..947533)
                     /locus_tag="Smed_4466"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(946499..>946855)
                     /locus_tag="Smed_4466"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(946499..>946855)
                     /locus_tag="Smed_4466"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(946736..946792)
                     /locus_tag="Smed_4466"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(947971..949008)
                     /locus_tag="Smed_4467"
                     /db_xref="GeneID:5318169"
     CDS             complement(947971..949008)
                     /locus_tag="Smed_4467"
                     /EC_number="3.6.3.17"
                     /note="TIGRFAM: D-xylose ABC transporter, periplasmic
                     substrate-binding protein;
                     KEGG: sme:SMb20902 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter periplasmic
                     substrate-binding protein"
                     /protein_id="YP_001313200.1"
                     /db_xref="GI:150376604"
                     /db_xref="InterPro:IPR013456"
                     /db_xref="GeneID:5318169"
                     /translation="MKSILKLMAGAAIIASMHSAAIAKDLVIGVSWSNFQEERWKTDE
                     AAIKTALEASGDKYISADAQSSAAKQLTDIESLIAQGANALIVLAQDSDAIGPAIEKA
                     AAEGIPVVGYDRLIENPAAFYITFDNKEVGRLQASEVFKQKPEGNYVFIKGSSADPNA
                     DFLFSGQMEVLKDAIDAGKIKNVGEAYTDGWKPENAQKNMEQFLTANDNKVDAIVASN
                     DGTAGGAIAALDAQGLAGSVPVSGQDADKAALNRVARGTQTVSVWKDSRELGKKAAEI
                     AAALAAGKTMDEIEGVQTFDGGPKGVAMKSVFLAPLAITRDNLNVVIDAGWIAKEETC
                     QGAKDDVAACK"
     misc_feature    complement(948001..949008)
                     /locus_tag="Smed_4467"
                     /note="ABC-type xylose transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     XylF; COG4213"
                     /db_xref="CDD:226668"
     sig_peptide     complement(948937..949008)
                     /locus_tag="Smed_4467"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.989 at
                     residue 24"
     misc_feature    complement(948208..948930)
                     /locus_tag="Smed_4467"
                     /note="Periplasmic xylose-binding component of the
                     ABC-type transport systems that belong to a family of
                     pentose/hexose sugar-binding proteins of the type I
                     periplasmic binding protein (PBP1) superfamily; Region:
                     PBP1_ABC_xylose_binding; cd01538"
                     /db_xref="CDD:107251"
     misc_feature    complement(order(948217..948219,948277..948279,
                     948520..948522,948670..948672,948892..948894))
                     /locus_tag="Smed_4467"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107251"
     gene            949400..950611
                     /locus_tag="Smed_4468"
                     /db_xref="GeneID:5318170"
     CDS             949400..950611
                     /locus_tag="Smed_4468"
                     /note="KEGG: sme:SMb20901 putative transcriptional
                     regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulator"
                     /protein_id="YP_001313201.1"
                     /db_xref="GI:150376605"
                     /db_xref="GeneID:5318170"
                     /translation="MMLTKSSTELVRQQNSALVLAALRRKGSLSHTEIAAQTGLASAT
                     ISVITAELERAGIIAKIERHVQGGRGRPRVLFEPRRDCGHVIVVRISSDVVQYSLADY
                     GGILLDRFEEVRGDLGGTAAFGEVLAAALERLLLRSNISKDEVLAISISSKGLVAADG
                     ARLIWSPVFGGEQLDFVKLLRPDWRARIMLSNESLLVAHALAVKEEEKQVGFRALAAV
                     SLGHSIGLGLARSGSSGELDVSAPNFGHMLHQDAAGLCRCGSFGCVEAAAGFYGILRT
                     AFEVPSNTIPAKFVPLSEMDKIAARARQGHRMAAYAFRQAGVALGNGISRMLSLYEPM
                     PIFVTGPGTRYFDLLQKGLEEGMAHSLQVRLEGMPQISVVIDEQRLVLDGHLDRALGA
                     IDGDIAASGHP"
     misc_feature    949454..949573
                     /locus_tag="Smed_4468"
                     /note="Winged helix-turn-helix DNA-binding; Region:
                     HTH_24; pfam13412"
                     /db_xref="CDD:205590"
     misc_feature    949631..950599
                     /locus_tag="Smed_4468"
                     /note="Transcriptional regulator/sugar kinase
                     [Transcription / Carbohydrate transport and metabolism];
                     Region: NagC; COG1940"
                     /db_xref="CDD:224851"
     misc_feature    <949826..950203
                     /locus_tag="Smed_4468"
                     /note="Nucleotide-Binding Domain of the sugar
                     kinase/HSP70/actin superfamily; Region:
                     NBD_sugar-kinase_HSP70_actin; cl17037"
                     /db_xref="CDD:247684"
     gene            complement(950746..951738)
                     /locus_tag="Smed_4469"
                     /db_xref="GeneID:5318171"
     CDS             complement(950746..951738)
                     /locus_tag="Smed_4469"
                     /note="PFAM: oxidoreductase domain protein; Oxidoreductase
                     domain;
                     KEGG: sme:SMb20899 hypothetical myo-inositol dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain-containing protein"
                     /protein_id="YP_001313202.1"
                     /db_xref="GI:150376606"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="GeneID:5318171"
                     /translation="MTVRFGLLGAGRIGKVHAKAVSANADARLVAVADAFPAAAEAIA
                     GAYGCEVRTIDAIQAGSDIDAVVICTPTDTHADLIERFARAGKAIFCEKPVDLDVERV
                     RACLKVVSETKAKLMVGFNRRFDPHFMAVRKAIDDGRIGEVEMVTITSRDPGAPPVDY
                     IKRSGGIFRDMTIHDFDMARFLLGEEPVSVTATAAVLVDMAIGEAGDYDSVSVILQTA
                     SGKQAIISNSRRATYGYDQRIEVHGSKGAVAAENQRPVSIEIATVDGYTRPPLHDFFM
                     TRYTEAYANEIESFVAAIEKGAEIAPSGEDGLAALALADAAVRSVAEKRQVSVA"
     misc_feature    complement(950749..951738)
                     /locus_tag="Smed_4469"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:223745"
     misc_feature    complement(951379..951732)
                     /locus_tag="Smed_4469"
                     /note="Oxidoreductase family, NAD-binding Rossmann fold;
                     Region: GFO_IDH_MocA; pfam01408"
                     /db_xref="CDD:201778"
     misc_feature    complement(951019..951345)
                     /locus_tag="Smed_4469"
                     /note="Oxidoreductase family, C-terminal alpha/beta
                     domain; Region: GFO_IDH_MocA_C; pfam02894"
                     /db_xref="CDD:217272"
     gene            952030..952284
                     /locus_tag="Smed_4470"
                     /db_xref="GeneID:5318172"
     CDS             952030..952284
                     /locus_tag="Smed_4470"
                     /note="KEGG: sme:SMb20898 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313203.1"
                     /db_xref="GI:150376607"
                     /db_xref="GeneID:5318172"
                     /translation="MIKFIDPDHPFYRPLWIRLLIIVFCAVWTAVEFYGGQTMWGTIF
                     LVVTAYAGATLLVFYRPKEEEQGKSGATGKTNEGTSDGTN"
     gene            complement(952288..952737)
                     /locus_tag="Smed_4471"
                     /db_xref="GeneID:5318173"
     CDS             complement(952288..952737)
                     /locus_tag="Smed_4471"
                     /note="KEGG: sme:SMb20897 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313204.1"
                     /db_xref="GI:150376608"
                     /db_xref="GeneID:5318173"
                     /translation="MFGISFFQSVLQRLRDEQDAEMLGEATGGPGTVIGTTSGFVPET
                     SSGTAATYTTVQQAYCELTPTESPAPFAIPDFLKRISLAEVASELALGEAETALTLAA
                     RRRRFAAANHPDRLPAEARLNATLRMKLANMLIDEAFRRIKKPSMPK"
     gene            complement(952800..953780)
                     /locus_tag="Smed_4472"
                     /db_xref="GeneID:5318174"
     CDS             complement(952800..953780)
                     /locus_tag="Smed_4472"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb20896 probable transcriptional regulator,
                     LysR family, possibly activator of the expression of ChvE
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001313205.1"
                     /db_xref="GI:150376609"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318174"
                     /translation="MLEGRPNASGPAGELLETGLFRSGLKINHLRLVLAIDDHRRISA
                     AADSLGISQPAASRMLAEIEAIAKAPICERVARGVELTSYGEALARRARTIFLELREA
                     AREINELKTGSGGSVSLGSVTGPALNLAVPAIRQVSTAYPGIEINVQIDNSNVLTREL
                     LAARHDFIIGRIPDDLNPRLFNLIEMGFEEVCLIVREGHPLLEKASVSADDLPGYDWV
                     FQPPGTLLRRAVEDSFGSAGVRLPATVINTSSTILTLSIVRNTNAIAPVALDVARLVA
                     GNGTEAGEIKILRTGFPIRIKPYGLITAEGRALPPSAKLLYDLILKQSRA"
     misc_feature    complement(952803..953708)
                     /locus_tag="Smed_4472"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    complement(953523..953702)
                     /locus_tag="Smed_4472"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    complement(952821..953408)
                     /locus_tag="Smed_4472"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cl11398"
                     /db_xref="CDD:245600"
     misc_feature    complement(order(953001..953006,953010..953015,
                     953031..953048,953331..953351,953355..953357,
                     953367..953369,953376..953381,953385..953390))
                     /locus_tag="Smed_4472"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            954054..955121
                     /locus_tag="Smed_4473"
                     /db_xref="GeneID:5318175"
     CDS             954054..955121
                     /locus_tag="Smed_4473"
                     /note="KEGG: sme:SMb20895 probable sugar uptake ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sugar uptake ABC transporter
                     periplasmic solute-binding protein"
                     /protein_id="YP_001313206.1"
                     /db_xref="GI:150376610"
                     /db_xref="GeneID:5318175"
                     /translation="MKFFTSLLAAAAMTVAGFAAPAVAQDKGMVGISMPTKTSTRWIS
                     DGETMEKLFKDAGYTPDLQFADDDIPNQLAQIENMVTKGAKVLVIGAIDGTTLSDILQ
                     KAADAGVKVIAYDRLIRDSGNVDYYATFDNFQVGVLQATSLVEGLKLDSATEPKNIEL
                     FGGSPDDNNAFFFYDGAMSVLQPLIDSGKLVVKSGQMGMDQVGTLRWDGAVAQARMEN
                     LLSSAYTDAKVDGVLSPYDGLSIGIISALKGVGYGSGDMPMPIVTGQDAELPSVKSIL
                     AGEQHSTVFKDTRELAKVTVNMVNAIMDGKEPEVNDTKTYENGVKVVPSYLLKPVSVD
                     KSNAKDVLVGSGYYTEDQLNN"
     misc_feature    954054..955118
                     /locus_tag="Smed_4473"
                     /note="ABC-type xylose transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     XylF; COG4213"
                     /db_xref="CDD:226668"
     sig_peptide     954054..954128
                     /locus_tag="Smed_4473"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.997 at
                     residue 25"
     misc_feature    954141..955043
                     /locus_tag="Smed_4473"
                     /note="Periplasmic xylose-binding component of the
                     ABC-type transport systems that belong to a family of
                     pentose/hexose sugar-binding proteins of the type I
                     periplasmic binding protein (PBP1) superfamily; Region:
                     PBP1_ABC_xylose_binding; cd01538"
                     /db_xref="CDD:107251"
     misc_feature    order(954174..954176,954396..954398,954570..954572,
                     954849..954851,954909..954911)
                     /locus_tag="Smed_4473"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107251"
     gene            955315..956850
                     /locus_tag="Smed_4474"
                     /db_xref="GeneID:5318176"
     CDS             955315..956850
                     /locus_tag="Smed_4474"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20894 probable sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313207.1"
                     /db_xref="GI:150376611"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318176"
                     /translation="MDNIILEMRGITKTFPGVKALDNVSFKVREGEIHALVGENGAGK
                     STLMKVLSGVYPAGTYEGEIHYDGKLRQFSTISDSEDLGIIIIHQELALVPLLSIAEN
                     IFLGNEVAEKGIIHWPQTFARTQELLKKVGLNESPATLITDIGVGKQQLVEIAKALSK
                     KVRLLILDEPTASLNENDSDALLKLLMEFRSQGMTSIIISHKLNEIKKVADQITILRD
                     GGTVETLDCHKEEVGEDRIINGMVGRAMEDRYPPREPKIGDTLLEVKNWNVYHQHHRD
                     RQFLHDVSFKVRAGEVVGIAGLMGAGRTETAMSIFGRSWGHKITGDVTMRGKPVDVST
                     IPKAIKAGLAYVTEDRKQLGLVLINNIMHNTTLSNLGAVSSNGVIDERKEARVASDYR
                     SKLRIRSHSIYQEAVNLSGGNQQKVVLSKWLFTNPEVLILDEPTRGIDIGAKYEIYTI
                     INQLAAEGKGILMISSEMPELLGTCDRIYVMNEGRIVAELSKEEASQESIMRAIMRSG
                     EKH"
     misc_feature    955315..956835
                     /locus_tag="Smed_4474"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    955330..955986
                     /locus_tag="Smed_4474"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    955426..955449
                     /locus_tag="Smed_4474"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(955435..955440,955444..955452,955579..955581,
                     955816..955821,955915..955917)
                     /locus_tag="Smed_4474"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    955570..955581
                     /locus_tag="Smed_4474"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(955603..955617,955759..955773)
                     /locus_tag="Smed_4474"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    955804..955821
                     /locus_tag="Smed_4474"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    955828..955839
                     /locus_tag="Smed_4474"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    955903..955923
                     /locus_tag="Smed_4474"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    956086..956772
                     /locus_tag="Smed_4474"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            956850..958064
                     /locus_tag="Smed_4475"
                     /db_xref="GeneID:5318177"
     CDS             956850..958064
                     /locus_tag="Smed_4475"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20893 probable sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001313208.1"
                     /db_xref="GI:150376612"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318177"
                     /translation="MVADTSTQTTKPSIGDYLRNNIREYGLLVALVIIMLFFQFVTNG
                     VLFRPVNITNLVLQNSFIVIMALGMLLIIVAGHIDLSVGSIVAFIGAISAIMLVKWGL
                     PAFVVVPACLVVGGTMGAAQGYWVAYQKIPAFIVTLAGMLVFRGMTYVVLGGRPIGPF
                     PKEFQILSTGFVPDFLYFLNPSPDLIKNMVALVAVLLLVGYAIYAGLRNRRINEQHGS
                     ENEPFIFFAIQMAVIGVVALFIGFQLSTYRGLPNVLIVMGVLIALYTFVTSRSTVGRR
                     IYAMGGNEKAAKLSGINTERLTFYAFVNMGALAALAGMIITARLNSATPKAGVGFELD
                     VIAACFIGGASASGGVGKITGAVIGALIMGVMNNGMSIMGIGIDYQQLIKGLVLLAAV
                     FFDVYNKNKGKG"
     misc_feature    957000..>957386
                     /locus_tag="Smed_4475"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    957024..>957359
                     /locus_tag="Smed_4475"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    <957549..958025
                     /locus_tag="Smed_4475"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    <957558..958034
                     /locus_tag="Smed_4475"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    957702..957758
                     /locus_tag="Smed_4475"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            958211..959206
                     /locus_tag="Smed_4476"
                     /db_xref="GeneID:5318341"
     CDS             958211..959206
                     /locus_tag="Smed_4476"
                     /note="PFAM: protein of unknown function DUF1238;
                     KEGG: sme:SMb20892 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313209.1"
                     /db_xref="GI:150376613"
                     /db_xref="InterPro:IPR009645"
                     /db_xref="GeneID:5318341"
                     /translation="MLISQVRKEDGSIIVAVRVPGETAHAVRGAESVYALAMEAANTG
                     RSLKDIIDARGLDETIDLQEAYSQGRLLSPITHPDPAHLHMTGTGLTHLGSAATRDAM
                     HKKATEAAEETLTDSMKMFRMGLEGGKPIPGERGVQPEWFYKGNGTSAVAPGEPLVSP
                     SFAEDGGEEPEMAGIYVISDKGVPYRLGFAVANEFSDHKTERVNYLWLAHSKLRQASF
                     GPEIRIGAAPEDIRGVSRIHRGGEVLWEKPFLSGEANMSHSFANLEYHHFKYGIFRAP
                     GDVHVHMFGTATLSFGDGIRTEEGDVFEIEAKEFGLPLRNPLAIAAEEEVAVHQL"
     misc_feature    958211..959203
                     /locus_tag="Smed_4476"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: GguC; COG3802"
                     /db_xref="CDD:226324"
     misc_feature    958622..959167
                     /locus_tag="Smed_4476"
                     /note="Fumarylacetoacetate (FAA) hydrolase family; Region:
                     FAA_hydrolase; pfam01557"
                     /db_xref="CDD:216570"
     gene            959217..960713
                     /locus_tag="Smed_4477"
                     /db_xref="GeneID:5318342"
     CDS             959217..960713
                     /locus_tag="Smed_4477"
                     /note="PFAM: aldehyde dehydrogenase;
                     KEGG: sme:SMb20891 putative dehydrogenase, possibly
                     aldehyde dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="YP_001313210.1"
                     /db_xref="GI:150376614"
                     /db_xref="InterPro:IPR002086"
                     /db_xref="GeneID:5318342"
                     /translation="MAGACRNPAVALAEEDKEAEAMTLHQNLIAGEWVGEDGVANVNP
                     SNTNDVVGDYARASAEDAKAAIAAAKAAFPTWSRSGILERHAILKKTADEILARKDEL
                     GRLLSREEGKTLAEGIGETVRAGQIFEFFAGETLRLAGEVVPSVRPGIGVEITREPVG
                     VVGIITPWNFPIAIPAWKVAPALCYGNTVVFKPAELVPGCSWAIVDILHRAGLPKGVL
                     NLVMGKGSVVGQAMLDSPDVQAITFTGSTATGKRVAVASVEHNRKYQLEMGGKNPFVV
                     LDDADLSVAVEAAVNSAFFSTGQRCTASSRIIVTEGIHDRFVAAMGERIKGLVVDDAL
                     KAGTHIGPVVDQSQLNQDTDYIAIGKKEGAKLAFGGELVSRDTPGFYLQPALFTEATN
                     DMRISREEIFGPVAAVIRVRDYDEALAVANDTPFGLSSGIATTSLKHATHFKRNAEAG
                     MVMVNLPTAGVDFHVPFGGRKASSYGPREQGKYAAEFYTNVKTAYTLA"
     misc_feature    959289..960704
                     /locus_tag="Smed_4477"
                     /note="Bacillus subtilis NADP+-dependent
                     alpha-ketoglutaric semialdehyde dehydrogenase ycbD-like;
                     Region: ALDH_KGSADH-YcbD; cd07097"
                     /db_xref="CDD:143415"
     misc_feature    959313..960695
                     /locus_tag="Smed_4477"
                     /note="Aldehyde dehydrogenase family; Region: Aldedh;
                     pfam00171"
                     /db_xref="CDD:215767"
     misc_feature    order(959709..959723,959745..959747,959790..959792,
                     959796..959801,959943..959954,959961..959963,
                     959970..959975,960015..960023,960117..960119,
                     960414..960416,960420..960422,960498..960500,
                     960615..960617)
                     /locus_tag="Smed_4477"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:143415"
     misc_feature    order(959721..959723,960015..960017,960108..960110,
                     960117..960119)
                     /locus_tag="Smed_4477"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143415"
     gene            960818..962563
                     /locus_tag="Smed_4478"
                     /db_xref="GeneID:5318343"
     CDS             960818..962563
                     /locus_tag="Smed_4478"
                     /EC_number="4.2.1.9"
                     /note="catalyzes the formation of 3-methyl-2-oxobutanoate
                     from 2,3,-dihydroxy-3-methylbutanoate"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="YP_001313211.1"
                     /db_xref="GI:150376615"
                     /db_xref="InterPro:IPR000581"
                     /db_xref="GeneID:5318343"
                     /translation="MKKKAEWPRKLRSQDWFGGTGKNAIMHRSWMKNQGLPADTFDGR
                     PIIGICNTWSELTPCNAHLRDLAERVKRGVYEAGGFPVEFPVFSTGESTLRPTAMMFR
                     NLAAMDVEESIRGNPIDGVVLLGGCDKTTPSLLMGAASVDIPAIVVSGGPMLNGKWRG
                     KDVGSGTAIWQFSEMVKSGEMTLEEFMDAEQGMARSAGSCMTMGTASTMASMAEALGM
                     TLSGNAAIPAVDARRRVISQLTGRRIVEMVKEDLKPSDILTKEAFENAIRVNGAVGGS
                     TNAVLHLLALAGRVGVDLSLDDWDRLGRDVPTIVNLQPSGKYLMEEFYYAGGLPVVIK
                     AVAEMGLLHNDAITVSGDTIWNDVKGVVNYNDDVILPRERALTKSGGIAVLRGNLAPR
                     GAVLKPSAASPNLMQHKGRAVVFESIEDYHARINREDLDIDETCIMVLKYCGPKGYPG
                     MAEVGNMGLPPKVLKKGVTDMIRISDARMSGTAYGTVILHTAPEAAEGGPLALVENGD
                     LIEVDIPNRTLHLHVSDEELARRRAAWVSPVKPLSGGYGSLYMKTVMQADAGADLDFL
                     VGPRGDRIPMDRDSH"
     misc_feature    960836..962560
                     /locus_tag="Smed_4478"
                     /note="dihydroxy-acid dehydratase; Validated; Region:
                     PRK06131"
                     /db_xref="CDD:235708"
     gene            962787..963467
                     /locus_tag="Smed_4479"
                     /db_xref="GeneID:5318344"
     CDS             962787..963467
                     /locus_tag="Smed_4479"
                     /note="KEGG: sme:SMb20889 hypothetical glycine-rich
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313212.1"
                     /db_xref="GI:150376616"
                     /db_xref="GeneID:5318344"
                     /translation="MPNKALVLSVGLLTSLAFSPSFAQSVGGNGGLNVGVSLGGSNGV
                     NANVGASLGGSRGVKADADASVGGSRGVNTSATASVGGSHGVNADVDASVGGSRGLNS
                     NVSANVGGSNGIDADANVSLGGRRGLNANVSANAGGGSGAGLGVGLGLGGSSAGGVGP
                     GSGGGAPGASGGAGIGAPGQSAVAAFNAMSPSERRMVLKRCRDVVNGGYDRGLVALCR
                     LLQSTASR"
     sig_peptide     962787..962858
                     /locus_tag="Smed_4479"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.966 at
                     residue 24"
     gene            complement(963611..964429)
                     /locus_tag="Smed_4480"
                     /db_xref="GeneID:5318345"
     CDS             complement(963611..964429)
                     /locus_tag="Smed_4480"
                     /note="PFAM: transglutaminase domain protein;
                     transglutaminase domain protein;
                     KEGG: sme:SMb20888 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="YP_001313213.1"
                     /db_xref="GI:150376617"
                     /db_xref="InterPro:IPR002931"
                     /db_xref="InterPro:IPR013589"
                     /db_xref="GeneID:5318345"
                     /translation="MHLKISHTTEYRYDAPVQYALQRLRLTPVNLPGQTVLNWKTLVD
                     GAAIEVSYDDQFGNRTHLVSVDADRTVLRIEAQGEVETEDRAGVFGLHHSFAPLWLYV
                     RETPLSKPGKRVRELAKAAVGSSELERMHSLMALVHAAVRYEPGETQVGTTAEEALER
                     GKGVCQDHAHVLISAARTLGLPARYVSGYLMMEDRTEQTASHAWADIHIAGLGWVGFD
                     AANKVCPDDRYVRIASGLCYRDAAPVSGLVHGFGAETLKVALTVEKQAQRQVQC"
     misc_feature    complement(963641..964429)
                     /locus_tag="Smed_4480"
                     /note="Transglutaminase-like enzymes, putative cysteine
                     proteases [Amino acid transport and metabolism]; Region:
                     COG1305"
                     /db_xref="CDD:224224"
     misc_feature    complement(964184..964426)
                     /locus_tag="Smed_4480"
                     /note="Bacterial transglutaminase-like N-terminal region;
                     Region: Bact_transglu_N; pfam08379"
                     /db_xref="CDD:149443"
     misc_feature    complement(963773..964087)
                     /locus_tag="Smed_4480"
                     /note="Transglutaminase-like superfamily; Region:
                     Transglut_core; pfam01841"
                     /db_xref="CDD:216735"
     gene            complement(964494..965435)
                     /locus_tag="Smed_4481"
                     /db_xref="GeneID:5318346"
     CDS             complement(964494..965435)
                     /locus_tag="Smed_4481"
                     /note="PFAM: protein of unknown function DUF403;
                     KEGG: sme:SMb20887 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313214.1"
                     /db_xref="GI:150376618"
                     /db_xref="InterPro:IPR007296"
                     /db_xref="GeneID:5318346"
                     /translation="MLGRTANGLYWMFRYIERTENSARLIDAGLRMSLTRSESAEDDW
                     DGVLQSAGVRGLYDQVHEGLTSGDAIDFLLRDRANPSSVISCIEEGRNNARMVRTALT
                     RETWEAINECWIEMKGILARRARTTDMPEIIDTIKRRTGLIRGAFHGTMLRNEIFNFS
                     RIGTFIERADNTARILDVKYYVLLPAISAVGSSIDNVQWESILRSVSAHRSYGWVYDA
                     ELRPANIADFLIANGRMPRSLAYCYEKIVSNLAYLAREYGKRHAAHETAERTLGFLRS
                     QSIANIMDRGLHEYLEDFISQNNRLGQEISDGYRFYH"
     misc_feature    complement(964500..965435)
                     /locus_tag="Smed_4481"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG2307"
                     /db_xref="CDD:225189"
     misc_feature    complement(964506..965435)
                     /locus_tag="Smed_4481"
                     /note="A predicted alpha-helical domain with a conserved
                     ER motif; Region: Alpha-E; pfam04168"
                     /db_xref="CDD:217938"
     gene            complement(965440..966849)
                     /locus_tag="Smed_4482"
                     /db_xref="GeneID:5318347"
     CDS             complement(965440..966849)
                     /locus_tag="Smed_4482"
                     /note="PFAM: protein of unknown function DUF404; protein
                     of unknown function DUF407;
                     KEGG: sme:SMb20886 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313215.1"
                     /db_xref="GI:150376619"
                     /db_xref="InterPro:IPR007297"
                     /db_xref="InterPro:IPR007302"
                     /db_xref="GeneID:5318347"
                     /translation="MAFDEMIDADGSPRQPYSTYHQWYSNQDRNRLIAKSKEAEKIFR
                     KTGITFAVYGHADSSEKLIPFDLIPRIISGREWRRLAQGIEQRVLALNAFLDDIYHKQ
                     EIIRAGRIPRGLIEKNDTFLPQMIGFRPSGGVYTHVVGTDIVRTGENQFYVLEDNART
                     PSGVSYMLENRETMMQMFPELFHQNRVRPVENYPYLLRQSLSSLAPAGCNGKPRVAVL
                     TPGIYNSAFYEHAFLADMMGVELVQGSDLRVIDGKVKMRTTRGYEAIDVLYRRVDDDF
                     LDPLTFRSDSALGIPGIMDVYRAGNVTIANAPGTGISDDKAIYSYMPEIIEFYTGRKP
                     LLENVPTWRCSEPDSLKYVLEHLAELVVKEVHGSGGYGMLVGPTATKKERVVFAEKLK
                     SRPGNYIAQPTLSLSTVPIMVKKGIAPRHVDLRPYVLVSDKVQIIPGGLTRVALKEGS
                     LVVNSSQGGGTKDTWVLED"
     misc_feature    complement(965443..966849)
                     /locus_tag="Smed_4482"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG2308"
                     /db_xref="CDD:225190"
     gene            967330..968247
                     /locus_tag="Smed_4483"
                     /db_xref="GeneID:5318348"
     CDS             967330..968247
                     /locus_tag="Smed_4483"
                     /note="PFAM: protein of unknown function DUF6
                     transmembrane;
                     KEGG: sme:SMb20885 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313216.1"
                     /db_xref="GI:150376620"
                     /db_xref="InterPro:IPR000620"
                     /db_xref="GeneID:5318348"
                     /translation="MLARLAPAIFVLLWSTGWVVAKYAAFFADPLTFLALRYSFAILL
                     FVCFCLLSGARWPRSPTAIGHAIVSGIFLHGLYLGAVWWAIGQGVPAAISGIIAGLQP
                     LMTAAVAPWLIGEKLNGQQKLGLVLGFCGIALAVAPKMLAIDASATPIHLLPLAVNVA
                     GMAAVTYGTLYQKRYLQNGDLRSIAALQYVGALIVTIPLALMLENLHVTWNLELVAAL
                     AWSVLGLSMGAIALLLYLIRRGQVSRAASLIYLVPPLAAGEAALFFGEALTVPMILGT
                     IIAVAGVYLTNRNAAEPAPSAVLDTQRPL"
     misc_feature    967330..968202
                     /locus_tag="Smed_4483"
                     /note="Permeases of the drug/metabolite transporter (DMT)
                     superfamily [Carbohydrate transport and metabolism / Amino
                     acid transport and metabolism / General function
                     prediction only]; Region: RhaT; COG0697"
                     /db_xref="CDD:223769"
     misc_feature    967363..967737
                     /locus_tag="Smed_4483"
                     /note="EamA-like transporter family; Region: EamA;
                     pfam00892"
                     /db_xref="CDD:216178"
     gene            complement(968351..969847)
                     /locus_tag="Smed_4484"
                     /db_xref="GeneID:5318349"
     CDS             complement(968351..969847)
                     /locus_tag="Smed_4484"
                     /note="PFAM: helicase domain protein; DEAD/DEAH box
                     helicase domain protein;
                     SMART: DEAD-like helicases;
                     KEGG: sme:SMb20880 putative ATP-dependent RNA helicase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="YP_001313217.1"
                     /db_xref="GI:150376621"
                     /db_xref="InterPro:IPR001650"
                     /db_xref="InterPro:IPR011545"
                     /db_xref="InterPro:IPR014001"
                     /db_xref="InterPro:IPR014014"
                     /db_xref="InterPro:IPR014021"
                     /db_xref="GeneID:5318349"
                     /translation="MSTFKELGLSQEILATLTANGFEKPTPIQTQAIPLVLQGRDLIG
                     LAQTGTGKTAAFGLPMIEKLQADGKRPDPRNIRALILAPTRELVNQIATNLKLFVKKT
                     PIKVGVVVGGVSINKQTEQLARGVDILVATPGRLLDLISRKAVTLTQGRYLVLDEADQ
                     MLDLGFIHDLRKIAKLVPKNRQTLLFSATMPKLIAELAGEYLTDPVKVEVTRPGKAAD
                     KVEQYVHFVPGKDLKTTILKQTLTANPDGLSLVFSRTKHGAEKLMKHLDQVGFKAASI
                     HGNKSQGQRERALKAFRDGEIRVLVATDVAARGIDIPGVTHVYNYDLPEVADAYVHRI
                     GRTARNGRDGIAIAFCAPDEIRLLRDIEKLMGIEIAVASGEVPADQARPSKGRGGRGN
                     AQSRGNGAGQRQGGPRRDRPQRQSAAGGFAGDELLRDDRSQQHERRDHRAPGQDGRPE
                     GNRNHEAKKHHGRPGPKRDGRRGNEGQPSNRNEGARGMRRAENRAPRG"
     misc_feature    complement(968705..969841)
                     /locus_tag="Smed_4484"
                     /note="helicase 45; Provisional; Region: PTZ00424"
                     /db_xref="CDD:185609"
     misc_feature    complement(969221..969838)
                     /locus_tag="Smed_4484"
                     /note="DEAD-box helicases. A diverse family of proteins
                     involved in ATP-dependent RNA unwinding, needed in a
                     variety of cellular processes including splicing, ribosome
                     biogenesis and RNA degradation. The name derives from the
                     sequence of the Walker  B motif; Region: DEADc; cd00268"
                     /db_xref="CDD:238167"
     misc_feature    complement(969689..969703)
                     /locus_tag="Smed_4484"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238167"
     misc_feature    complement(969371..969382)
                     /locus_tag="Smed_4484"
                     /note="Mg++ binding site [ion binding]; other site"
                     /db_xref="CDD:238167"
     misc_feature    complement(969281..969289)
                     /locus_tag="Smed_4484"
                     /note="motif III; other site"
                     /db_xref="CDD:238167"
     misc_feature    complement(968801..969193)
                     /locus_tag="Smed_4484"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:238034"
     misc_feature    complement(order(968933..968941,969014..969019,
                     969077..969088))
                     /locus_tag="Smed_4484"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:238034"
     misc_feature    complement(order(968831..968833,968840..968842,
                     968852..968854,968915..968917))
                     /locus_tag="Smed_4484"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:238034"
     gene            970404..970922
                     /locus_tag="Smed_4485"
                     /db_xref="GeneID:5318350"
     CDS             970404..970922
                     /locus_tag="Smed_4485"
                     /note="KEGG: sme:SMb20879 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313218.1"
                     /db_xref="GI:150376622"
                     /db_xref="GeneID:5318350"
                     /translation="MRSQPFCPRAPLTYLPSTRETIVRNRIWILAADGNTARIVKDVN
                     LLKDGRQQPEVETFQIETKRRQDIMADKPGRSHSSAGHGRSAMEYSSDPVREEQHRFA
                     MEIAGKLEHYADERAFENLVICAAPRTLGDLRKLLSHQVKEKTLAEIDRNCVSVPTDQ
                     LIATVKSVVFPG"
     misc_feature    970482..970907
                     /locus_tag="Smed_4485"
                     /note="Protein required for attachment to host cells;
                     Region: Host_attach; cl02398"
                     /db_xref="CDD:243020"
     gene            complement(971016..971741)
                     /locus_tag="Smed_4486"
                     /db_xref="GeneID:5319178"
     CDS             complement(971016..971741)
                     /locus_tag="Smed_4486"
                     /note="PFAM: protein of unknown function DUF752;
                     KEGG: sme:SMb20878 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313219.1"
                     /db_xref="GI:150376623"
                     /db_xref="InterPro:IPR008471"
                     /db_xref="GeneID:5319178"
                     /translation="MTGTDPGKSPSPSRQNLEWHEGDMPYSTEFGDHFYCRTDGRLEC
                     GHVFLAGNGLPERWGSGGAMTIGELGFGTGLNFCETWRQWKRVPAPRKCLHFVSFERF
                     PMHAGEIDRALAHWPEIDEERQALVANWPTDPVARVDIDFTAEVRLTIVIGAAFGGVS
                     TSPPNFDAWYLDGFAPSRNPDMWSKELMQLVFDRTVGGGSFATYAAAGFVRRNLAAAG
                     FAVERRPGFAGKREMLRGVKPAI"
     misc_feature    complement(971022..971723)
                     /locus_tag="Smed_4486"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG4121"
                     /db_xref="CDD:226606"
     gene            971781..972911
                     /locus_tag="Smed_4487"
                     /db_xref="GeneID:5319179"
     CDS             971781..972911
                     /locus_tag="Smed_4487"
                     /note="PFAM: FAD dependent oxidoreductase;
                     KEGG: sme:SMb20877 putative oxidoreductase, possibly
                     D-amino acid oxidase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD dependent oxidoreductase"
                     /protein_id="YP_001313220.1"
                     /db_xref="GI:150376624"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="GeneID:5319179"
                     /translation="MCEVLIVGGGIMGLWAAVMAGRAGFTTRLLERWRIGSGASGGFL
                     GALMPHMPDRWNEKKQFQFDALVSLEGEIAELEAATGLSAGYRRSGRVMPIGRAHLRE
                     IAHGRERDAAQNWRGPAHQYLWQVGHADEGGWPAADAAPFGIVQDTLAARVAPRNLLA
                     VLRAALDQFPHVQCEEGAEVVSIEPARGRLLLADGRALTFDRLILAAGVASFGFIDGL
                     TQPRRSASGGAVKGQAALFRADVDKALPIIFTEGLYIVPHENGQVAVGSTSESRFDDP
                     NFTDRQLDALLARAIDIAPVLRSATVIERWAGLRPRATGLEPMVGRHPDHERLFVLTG
                     GFKVSFGLAHALARSVVEEIAGGGMNALPESFQCAHHVAALR"
     misc_feature    971781..972851
                     /locus_tag="Smed_4487"
                     /note="Glycine/D-amino acid oxidases (deaminating) [Amino
                     acid transport and metabolism]; Region: DadA; COG0665"
                     /db_xref="CDD:223737"
     gene            973034..973849
                     /locus_tag="Smed_4488"
                     /db_xref="GeneID:5319180"
     CDS             973034..973849
                     /locus_tag="Smed_4488"
                     /note="PFAM: protein of unknown function DUF1045;
                     KEGG: sme:SMb20876 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313221.1"
                     /db_xref="GI:150376625"
                     /db_xref="InterPro:IPR009389"
                     /db_xref="GeneID:5319180"
                     /translation="MRYAICFTPPMGDPLSVTAASWLGRSVYTGEPVELPSIAGLAVS
                     DIAFHTAVARRFGFHAMIMAPFCLRPCMDEAQLLKAMMLFTSDETPFEIERLEVARLS
                     QCWGLMPQMPSQPMHLLAARVIQAFDRFRSPLSEEDIERADPDRLTAPQFTNLHRWGD
                     PHVMDEYRFHMALTGPLNADAGRRVEAPLRQLFESLLIEPLLIGSLALFIEHEPGAPM
                     RVHSQHPLGKVSARPRGDKARHLVAARSVQDDAATPPAPVTAGISSGLAFRAG"
     misc_feature    973214..973693
                     /locus_tag="Smed_4488"
                     /note="Protein of unknown function (DUF1045); Region:
                     DUF1045; pfam06299"
                     /db_xref="CDD:218980"
     gene            973981..974910
                     /locus_tag="Smed_4489"
                     /db_xref="GeneID:5319181"
     CDS             973981..974910
                     /locus_tag="Smed_4489"
                     /EC_number="3.5.1.41"
                     /note="PFAM: polysaccharide deacetylase;
                     KEGG: sme:SMb20875 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="chitin deacetylase"
                     /protein_id="YP_001313222.1"
                     /db_xref="GI:150376626"
                     /db_xref="InterPro:IPR002509"
                     /db_xref="GeneID:5319181"
                     /translation="MNENSYPRDFVGYGRRPPEARWPGDANIAVQFVLNYEEGGESCI
                     LDGDPASECLLSEIVGAQPWAGQRNLNMESIYEYGARAGFWRLWRMFTSRGVTLTVYG
                     VTLAMARNPEAVAAMKEAGWEIASHGLRWLEYKDVPEEVERQHIREVVRLHTELTGER
                     PLGIYQGKPSANTLKLVLEEGGFLYSCDSYADELPYWVPGRTPDNPHLIIPYTLDAND
                     MRFATSQGFNSGDQFFTYLKDTFDVLYAEGKEGSPKMMNVGLHCRLVGRPGRAAALAR
                     FIDYVTSHDKVWVPRRIDIARHWYEHHKPTEAR"
     misc_feature    973996..974895
                     /locus_tag="Smed_4489"
                     /note="putative urate catabolism protein; Region:
                     uraD_N-term-dom; TIGR03212"
                     /db_xref="CDD:211797"
     misc_feature    974044..974874
                     /locus_tag="Smed_4489"
                     /note="Catalytic domain of bacterial PuuE allantoinases,
                     Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1),
                     and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977"
                     /db_xref="CDD:200599"
     misc_feature    order(974083..974085,974089..974091,974140..974142,
                     974359..974361,974371..974373,974476..974484,
                     974761..974763)
                     /locus_tag="Smed_4489"
                     /note="active site"
                     /db_xref="CDD:200599"
     misc_feature    order(974089..974091,974761..974763)
                     /locus_tag="Smed_4489"
                     /note="catalytic site [active]"
                     /db_xref="CDD:200599"
     misc_feature    order(974095..974097,974101..974103,974113..974118,
                     974149..974157,974179..974184,974188..974193,
                     974197..974214,974218..974226,974233..974238,
                     974245..974247,974305..974310,974383..974388,
                     974479..974481,974485..974493,974545..974559,
                     974566..974568,974620..974625,974638..974643,
                     974653..974667,974674..974676,974683..974688,
                     974695..974700,974707..974712,974719..974721,
                     974782..974790,974794..974796)
                     /locus_tag="Smed_4489"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:200599"
     gene            974910..975413
                     /locus_tag="Smed_4490"
                     /db_xref="GeneID:5319182"
     CDS             974910..975413
                     /locus_tag="Smed_4490"
                     /note="KEGG: sme:SMb20874 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313223.1"
                     /db_xref="GI:150376627"
                     /db_xref="GeneID:5319182"
                     /translation="MLTRDDFIRRFGGIFEHSPWVAERAYDRAASAGLTAGNVHSALC
                     NAFREASPADRLRVLRAHPDLAGKLAVAGELTADSKAEQASAGLDRLSPEEHARFTEL
                     NSAYIKKFGFPFIIAVKGLVKEDILAAFEQRIDNSAEEEFEAACAEVERIARLRLRSM
                     LPGDDYA"
     misc_feature    974910..975407
                     /locus_tag="Smed_4490"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3195"
                     /db_xref="CDD:225736"
     gene            975501..976007
                     /locus_tag="Smed_4491"
                     /db_xref="GeneID:5319183"
     CDS             975501..976007
                     /locus_tag="Smed_4491"
                     /EC_number="3.5.3.19"
                     /note="catalyzes the formation of glyoxylate from
                     (S)-ureidoglycolate"
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate hydrolase"
                     /protein_id="YP_001313224.1"
                     /db_xref="GI:150376628"
                     /db_xref="InterPro:IPR007247"
                     /db_xref="GeneID:5319183"
                     /translation="MSHLLSIEPLTREAFAPFGSIMEADPASMRFINGGNTERFHALA
                     RVDAAGEGAGAIINIFRGQPRVFPYSVTMMERHPLGSQSFSPLQDRPWLVVVAEDEGG
                     RPGRPRVFLANGRQGVNYARNIWHHPLMSVGVASDFIVVDREGPGSNLEEFYYDEAFV
                     IRDPFEGG"
     misc_feature    975504..975992
                     /locus_tag="Smed_4491"
                     /note="Ureidoglycolate hydrolase [Nucleotide transport and
                     metabolism]; Region: DAL3; COG3194"
                     /db_xref="CDD:225735"
     misc_feature    975504..975971
                     /locus_tag="Smed_4491"
                     /note="ureidoglycolate hydrolase; Provisional; Region:
                     PRK03606"
                     /db_xref="CDD:179606"
     gene            976237..976599
                     /locus_tag="Smed_4492"
                     /db_xref="GeneID:5319184"
     CDS             976237..976599
                     /locus_tag="Smed_4492"
                     /note="TIGRFAM: Hydroxyisourate hydrolase;
                     PFAM: Transthyretin;
                     KEGG: sme:SMb20872 conserved hypothetical protein,
                     transthyretin-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="YP_001313225.1"
                     /db_xref="GI:150376629"
                     /db_xref="InterPro:IPR000895"
                     /db_xref="InterPro:IPR014306"
                     /db_xref="GeneID:5319184"
                     /translation="MSKTGRLTTHVLDTALGRPAQAMRIDLYRLEGEVRQLIRTARTN
                     SDGRIDEPLVEGVDFTNGTYELVFHAGEYLRAMDVALPDPAFLDLVPLRFGVADSRNH
                     YHVPLLLSPYGYSTYRGS"
     misc_feature    976249..976596
                     /locus_tag="Smed_4492"
                     /note="HIUase (5-hydroxyisourate hydrolase) catalyzes the
                     second step in a three-step ureide pathway in which
                     5-hydroxyisourate (HIU), a product of the uricase (urate
                     oxidase) reaction, is hydrolyzed to
                     2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU);
                     Region: TLP_HIUase; cd05822"
                     /db_xref="CDD:100114"
     misc_feature    order(976264..976266,976270..976272,976378..976380,
                     976546..976548,976552..976554,976558..976560,
                     976585..976587)
                     /locus_tag="Smed_4492"
                     /note="active site"
                     /db_xref="CDD:100114"
     misc_feature    order(976276..976287,976492..976497,976501..976503,
                     976513..976521,976564..976566,976570..976590)
                     /locus_tag="Smed_4492"
                     /note="homotetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100114"
     gene            complement(976642..977778)
                     /locus_tag="Smed_4493"
                     /db_xref="GeneID:5319185"
     CDS             complement(976642..977778)
                     /locus_tag="Smed_4493"
                     /EC_number="1.1.2.3"
                     /note="PFAM: FMN-dependent alpha-hydroxy acid
                     dehydrogenase;
                     KEGG: sme:SMb20850 putative L-lactate dehydrogenase
                     (cytochrome) protein"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="YP_001313226.1"
                     /db_xref="GI:150376630"
                     /db_xref="InterPro:IPR000262"
                     /db_xref="InterPro:IPR008259"
                     /db_xref="GeneID:5319185"
                     /translation="MTQILEIRDLKALARRRVPKLFFDYADSGAWTEGTYRANEEDFA
                     RIKLRQRVLVDMSDRSLETTMIGQKVSMPVALAPTGLTGMQHADGEMLAAQAAEAFGI
                     PFTLSTMSICSIEDVASATTKPFWFQLYVMREREFVLNLIDRAKAAKCSALVLTLDLQ
                     ILGQRHKDLRNGLSAPPRLTPKHLWMMATRPGWCMKMLGTNRRTFGNIVGHAKSVSDL
                     SSLQVWTNEQFDPQLSWKDVEWIKERWGGPLILKGILDPEDAKMAAKSGADAIIVSNH
                     GGRQLDGAHSSISMLPRIVDAVGDQIEVHLDGGIRSGQDVLKAVALGAKGTYIGRPFL
                     YGLGALGKEGVRIALDIIRKEMDTTMALCGKRRITDVGLDVIAD"
     misc_feature    complement(976651..977760)
                     /locus_tag="Smed_4493"
                     /note="Isopentenyl diphosphate isomerase (BS_ypgA, MTH48
                     and related proteins) [Coenzyme transport and metabolism];
                     Region: idi; COG1304"
                     /db_xref="CDD:224223"
     misc_feature    complement(976651..977757)
                     /locus_tag="Smed_4493"
                     /note="TIM barrel proteins share a structurally conserved
                     phosphate binding motif and in general share an eight
                     beta/alpha closed barrel structure. Specific for this
                     family is the conserved phosphate binding site at the
                     edges of strands 7 and 8. The phosphate...; Region:
                     TIM_phosphate_binding; cl17186"
                     /db_xref="CDD:247740"
     misc_feature    complement(order(976786..976791,976852..976857))
                     /locus_tag="Smed_4493"
                     /note="phosphate binding site [ion binding]; other site"
                     /db_xref="CDD:240073"
     gene            complement(977901..979208)
                     /locus_tag="Smed_4494"
                     /db_xref="GeneID:5319186"
     CDS             complement(977901..979208)
                     /locus_tag="Smed_4494"
                     /note="Catalyzes the deamination of guanine"
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="YP_001313227.1"
                     /db_xref="GI:150376631"
                     /db_xref="InterPro:IPR006680"
                     /db_xref="InterPro:IPR011550"
                     /db_xref="InterPro:IPR013108"
                     /db_xref="InterPro:IPR014311"
                     /db_xref="GeneID:5319186"
                     /translation="MTAILIRGRTLSFHREPQGIDDKASYAYESDGALLVENGVITAS
                     GAYAMVQAGAPENVAEVDHRPDLIVPGFIDTHLHFPQMQVMASYAANLLEWLNSYTFP
                     EECRFVETAHAERIARHFFDEMVRHGTTTAAAYCSVHKTSADAFFAESVKRGMCMVAG
                     KVMMDRNAPQGLLDTPETSYDETRAVIADWHGKGRNHVAITPRFAITSTPEQMEAVRS
                     LVDEFPDLHVQTHLSENRDEIAYTLELYPEAADYTDVYARYGLLGPKSLFGHCIHLSE
                     READAMSDTGSIAVFCPTSNLFLGSGLFPLRALTRRQRPVRVSVASDIGGGTSYSMMK
                     TLDEAYKILQLQGERLNPFDSFYMMTRGNAEALSLAGRIGTLEPGTDADLAVLDMAAT
                     PAMALRAEVVNSLADELFLLQTMGDDRAVVETYVAGKPCKSML"
     misc_feature    complement(977910..979208)
                     /locus_tag="Smed_4494"
                     /note="guanine deaminase; Provisional; Region: PRK09228"
                     /db_xref="CDD:236419"
     misc_feature    complement(977925..979193)
                     /locus_tag="Smed_4494"
                     /note="Guanine deaminase (GDEase). Guanine deaminase is an
                     aminohydrolase responsible for the conversion of guanine
                     to xanthine and ammonia, the first step to utilize guanine
                     as a nitrogen source. This reaction also removes the
                     guanine base from the pool and...; Region: GDEase;
                     cd01303"
                     /db_xref="CDD:238628"
     misc_feature    complement(order(978240..978242,978399..978401,
                     978507..978509,978516..978518,978975..978977,
                     978981..978983))
                     /locus_tag="Smed_4494"
                     /note="active site"
                     /db_xref="CDD:238628"
     gene            complement(979205..980437)
                     /locus_tag="Smed_4495"
                     /db_xref="GeneID:5319187"
     CDS             complement(979205..980437)
                     /locus_tag="Smed_4495"
                     /note="PFAM: protein of unknown function DUF989;
                     KEGG: sme:SMb20848 conserved hypothetical membrane
                     protein, paralogue of Y21292"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313228.1"
                     /db_xref="GI:150376632"
                     /db_xref="InterPro:IPR009056"
                     /db_xref="InterPro:IPR010389"
                     /db_xref="GeneID:5319187"
                     /translation="MYEFAIAWEWLAFAARWLHVVTAIAWIGSSFYFIALDLGLVRRD
                     HLPPGAYGEEWQVHGGGFYHIQKYLVAPAAMPEHLTWFKWESYATWLSGFAMLCIVYY
                     GGADLFLIDRHVLDISAMTAILISLASLGLGWILYDLLCKSPVGKSTWGLMALLYLVL
                     VAMAWGYTQVFTGRAAFLHLGAFTATIMSANVFFIIIPNQKIVVGDLIAGRTPDPKLG
                     AQAKQRSLHNNYLTLPVIFFMLSNHYPLAFATAFNWVIAGLVFLMGVTIRHWFNTTHA
                     RKGKPTWTWAVTALLFILVMWLSTVPEILTVEERAETAPEFQRFADNAHFPAVSETIS
                     TRCSMCHAAEPAYEGIVRPPNGVKLESEAEIAARAREIYIQAGRSHAMPPGNITEMTD
                     EERRLVTAWFESAVGETR"
     misc_feature    complement(979211..980431)
                     /locus_tag="Smed_4495"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG3748"
                     /db_xref="CDD:226271"
     misc_feature    complement(979535..980428)
                     /locus_tag="Smed_4495"
                     /note="Protein of unknown function (DUF989); Region:
                     DUF989; pfam06181"
                     /db_xref="CDD:218928"
     misc_feature    complement(979226..979456)
                     /locus_tag="Smed_4495"
                     /note="Cytochrome c; Region: Cytochrom_C; pfam00034"
                     /db_xref="CDD:215669"
     gene            complement(980560..981489)
                     /locus_tag="Smed_4496"
                     /db_xref="GeneID:5319188"
     CDS             complement(980560..981489)
                     /locus_tag="Smed_4496"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb20847 putative transcriptional regulator,
                     LysR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001313229.1"
                     /db_xref="GI:150376633"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5319188"
                     /translation="MHQENLSMKMSKQFPLNALRVFEAAARLGSFTKAGDELGMTQTA
                     VSYQIRLIEENIGEPLFLRRPRQIALTEVGQHLAPKVTEAFEMLHDAVASARGNAEAA
                     LLINSTATFASQWLAREIGTFQLEHPNIAVRLVANDAIIDFNKEAVDVAIRSGMGDWP
                     GLASHRLMRVEFTPMLSPALAETVGGVRTPRDLLKLRIIDPRDPWWSLWFRAAGVDDP
                     DLDGRPGSRLGAQAFEARAAVAGQGVAILMPEFYSDDVALGRLYQPFELRCSDGHDYW
                     LVYPHARRNAPKIRAFRDWILGKLDPDTHRDAH"
     misc_feature    complement(980599..981462)
                     /locus_tag="Smed_4496"
                     /note="DNA-binding transcriptional activator GcvA;
                     Provisional; Region: PRK11139"
                     /db_xref="CDD:182990"
     misc_feature    complement(981265..981444)
                     /locus_tag="Smed_4496"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    complement(980602..981186)
                     /locus_tag="Smed_4496"
                     /note="The C-terminal substrate domain of LysR-type GcdR,
                     TrPI, HvR and beta-lactamase regulators, and that of other
                     closely related homologs; contains the type 2 periplasmic
                     binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like;
                     cd08432"
                     /db_xref="CDD:176123"
     misc_feature    complement(order(981082..981102,981106..981159,
                     981163..981186))
                     /locus_tag="Smed_4496"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176123"
     misc_feature    complement(order(980737..980739,980797..980805,
                     981157..981159,981163..981168))
                     /locus_tag="Smed_4496"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:176123"
     gene            981571..981774
                     /locus_tag="Smed_4497"
                     /db_xref="GeneID:5317937"
     CDS             981571..981774
                     /locus_tag="Smed_4497"
                     /note="KEGG: sme:SMb21676 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313230.1"
                     /db_xref="GI:150376634"
                     /db_xref="GeneID:5317937"
                     /translation="MSCDVSEFAERRPLIPLGGVVRLAASALRRMRGHSISLDLDSTS
                     DYMKKDLGLLDGRMARQDDDILR"
     gene            complement(981782..984139)
                     /locus_tag="Smed_4498"
                     /db_xref="GeneID:5317938"
     CDS             complement(981782..984139)
                     /locus_tag="Smed_4498"
                     /EC_number="1.17.1.4"
                     /note="TIGRFAM: Xanthine dehydrogenase molybdopterin
                     binding subunit;
                     PFAM: aldehyde oxidase and xanthine dehydrogenase a/b
                     hammerhead; aldehyde oxidase and xanthine dehydrogenase
                     molybdopterin binding;
                     KEGG: sme:SMb20846 probable xanthine dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdopterin binding
                     subunit"
                     /protein_id="YP_001313231.1"
                     /db_xref="GI:150376635"
                     /db_xref="InterPro:IPR000674"
                     /db_xref="InterPro:IPR008274"
                     /db_xref="InterPro:IPR014309"
                     /db_xref="GeneID:5317938"
                     /translation="MSADIHMDKPNLEVSNITGPMHAPLRHDSAHKHVAGTADYIDDM
                     PEPNGTLHGALGLTDRPHAEILAMDLSAVAALPGVVSVLTARDMPHSNDISPTHLHDE
                     PVLADGLIQFHGQPAFAVIAETRDIARRAARLAKITYRDLPPAIDVIDAMATGGTLIT
                     PPLTLERGDALGELERAPRRLQGRMRIGGQEHFYLEGHIALAIPGEDDEITVWVSTQH
                     PSEVQRMVAQVLGVPSNAVTVNVRRMGGAFGGKETQGNQFAALAAVAARKLRRAVKFR
                     PDRDDDMVATGKRHDFLVDYDVGFNDDGRIRAVQANYAARCGYSADLSGPVTDRALFH
                     ADNAYFYPHVKLTSQPLKTNTVSNTAFRGFGGPQGMLGGERIIEEIAYALGKDPLDIR
                     KLNFYGDAASGRNVTPYHQTIEDNIIGRIVDELEGSADYRARRAAIVEFNRSSRVIRK
                     GIALTPVKFGISFTLTHLNQAGALVHVYTDGSVHLNHGGTEMGQGVYTKVAQVLADSF
                     QIDIELVKITATTTGKVPNTSATAASSGSDLNGMAAFDAAHQIKERLVAFAAERWQTT
                     AENVTFEANHVRIGQELIPFAQLVQEAYGARVQLSAAGFYATPHIHWDRAAGRGTPFY
                     YFAYGAAISEVSVDTLTGEYMVDRVDVLHDVGRSLNPAIDLGQIEGGFVQGMGWLTTE
                     ELWWDEKGRLGTHAPSTYKIPLASDRPKIFNVRLAEWSENLEETIGKSKAVGEPPLML
                     PISVVEALSMAVASIIDYRECPRLDTPATPERVLMAVERLRAFPG"
     misc_feature    complement(981797..984079)
                     /locus_tag="Smed_4498"
                     /note="xanthine dehydrogenase, molybdopterin binding
                     subunit; Region: xanthine_xdhB; TIGR02965"
                     /db_xref="CDD:200222"
     misc_feature    complement(983711..984034)
                     /locus_tag="Smed_4498"
                     /note="Aldehyde oxidase and xanthine dehydrogenase, a/b
                     hammerhead domain; Region: Ald_Xan_dh_C; smart01008"
                     /db_xref="CDD:214971"
     misc_feature    complement(982013..983644)
                     /locus_tag="Smed_4498"
                     /note="Molybdopterin-binding domain of aldehyde
                     dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738"
                     /db_xref="CDD:217210"
     gene            complement(984136..985626)
                     /locus_tag="Smed_4499"
                     /db_xref="GeneID:5317939"
     CDS             complement(984136..985626)
                     /locus_tag="Smed_4499"
                     /note="TIGRFAM: Xanthine dehydrogenase small subunit;
                     PFAM: ferredoxin; molybdopterin dehydrogenase FAD-binding;
                     [2Fe-2S]-binding domain protein; CO dehydrogenase
                     flavoprotein domain protein;
                     KEGG: sme:SMb21011 probable xanthine dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase small subunit"
                     /protein_id="YP_001313232.1"
                     /db_xref="GI:150376636"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR002346"
                     /db_xref="InterPro:IPR002888"
                     /db_xref="InterPro:IPR005107"
                     /db_xref="InterPro:IPR006058"
                     /db_xref="InterPro:IPR014307"
                     /db_xref="GeneID:5317939"
                     /translation="MEQAPDSIRFILNDTEIALSDVAPTATLLDYLRLERRLTGTKEG
                     CAEGDCGACTVLVGRLAHDGEGGETTLVYESVNACIRFMGSLNATHIVTVEHLAGKDG
                     KLHPVQQALVDFHGSQCGFCTPGIVMSLYGLWLTNDRPGRAAIEKALQGNLCRCTGYE
                     PIVRAAEAAAADRPDVLFDPITRVREAVRARLQELRQAERIEIRSGVDCLIVPADAAD
                     LARVLADRPAATIVAGCTDVGLWVTKQMRPLNTVVFVNGIAELQRIESSKAGLTIGAG
                     VSYSAAYEALSSAYPSFGRLLDRVGGDQVRNMGTIGGNIANGSPIGDSPPPLIVLGAT
                     LTLRSHGGSRTLPLEDFFIAYGKQDRRPGEFVESIFVPALPAGERFAAYKISKRRDED
                     ISALLGAFRISLDGDRVKAARIAFGGMAATPKRAKVVEAALLGELWNEGTIRDAQSAF
                     DTDYQPITDWRATGAYRLLAAKNLLMRFFLESTGETAQLRRFEEVA"
     misc_feature    complement(984139..985611)
                     /locus_tag="Smed_4499"
                     /note="Xanthine dehydrogenase, iron-sulfur cluster and
                     FAD-binding subunit A [Nucleotide transport and
                     metabolism]; Region: XdhA; COG4630"
                     /db_xref="CDD:226977"
     misc_feature    complement(985387..985605)
                     /locus_tag="Smed_4499"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(985390..985395,985468..985479,
                     985483..985485,985492..985494,985501..985506))
                     /locus_tag="Smed_4499"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    complement(order(985390..985392,985468..985470,
                     985477..985479,985492..985494))
                     /locus_tag="Smed_4499"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     misc_feature    complement(985135..985350)
                     /locus_tag="Smed_4499"
                     /note="[2Fe-2S] binding domain; Region: Fer2_2; pfam01799"
                     /db_xref="CDD:201981"
     misc_feature    complement(984184..984486)
                     /locus_tag="Smed_4499"
                     /note="CO dehydrogenase flavoprotein C-terminal domain;
                     Region: CO_deh_flav_C; pfam03450"
                     /db_xref="CDD:217566"
     gene            complement(985653..986429)
                     /locus_tag="Smed_4500"
                     /db_xref="GeneID:5317940"
     CDS             complement(985653..986429)
                     /locus_tag="Smed_4500"
                     /note="TIGRFAM: 3-hydroxybutyrate dehydrogenase;
                     PFAM: short-chain dehydrogenase/reductase SDR; KR domain
                     protein;
                     KEGG: sme:SMb21010 D-beta-hydroxybutyrate dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="YP_001313233.1"
                     /db_xref="GI:150376637"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR002424"
                     /db_xref="InterPro:IPR011294"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5317940"
                     /translation="MVKTAVITGSTSGIGLAIARALAKTGANIVLNGFGTADEIRTVT
                     DEVAGLTSGSVLHHPADMTKPSEIAEMMATAASRFGGADILVNNAGVQFVEKIEDFPA
                     EQWDRIVAINLSSSFHTIRAAIPPMKKNGWGRIINIASAHGLVASPFKSAYVAAKHGI
                     MGLTKTVALEVAENGITVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQ
                     PTKKFITVEQVASLALYLASDDASQITGTHVSMDGGWTAQ"
     sig_peptide     complement(986358..986429)
                     /locus_tag="Smed_4500"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.988) with cleavage site probability 0.967 at
                     residue 24"
     misc_feature    complement(985656..986423)
                     /locus_tag="Smed_4500"
                     /note="d-3-hydroxybutyrate dehydrogenase (HBDH), classical
                     (c) SDRs; Region: HBDH_SDR_c; cd08940"
                     /db_xref="CDD:187644"
     misc_feature    complement(985656..986423)
                     /locus_tag="Smed_4500"
                     /note="3-hydroxybutyrate dehydrogenase; Region: PHB_DH;
                     TIGR01963"
                     /db_xref="CDD:211705"
     misc_feature    complement(order(985857..985868,985872..985883,
                     985959..985961,985971..985973,986010..986018,
                     986097..986099,986160..986168,986244..986252,
                     986328..986336,986388..986399,986403..986405))
                     /locus_tag="Smed_4500"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187644"
     misc_feature    complement(order(985656..985661,985668..985685,
                     985689..985706,985710..985712,985725..985727,
                     985734..985739,985746..985748,985758..985766,
                     985770..985775,985911..985916,985920..985925,
                     985929..985937,985941..985946,985953..985958,
                     985965..985970,985977..986000,986046..986048,
                     986055..986060,986067..986072,986076..986081,
                     986088..986093,986103..986105,986115..986117,
                     986124..986126,986130..986132,986136..986147,
                     986223..986225))
                     /locus_tag="Smed_4500"
                     /note="homotetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187644"
     misc_feature    complement(order(985920..985925,985929..985937,
                     985941..985946,985953..985958,985965..985970,
                     985977..985994,985998..986000,986046..986048,
                     986055..986060,986067..986072,986076..986081,
                     986088..986090,986103..986105,986115..986117,
                     986124..986126,986130..986132,986136..986147,
                     986223..986225))
                     /locus_tag="Smed_4500"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187644"
     misc_feature    complement(order(985665..985667,985848..985850,
                     985860..985862,985875..985880,985971..985973,
                     985980..985982,986004..986006,986010..986012,
                     986154..986156))
                     /locus_tag="Smed_4500"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187644"
     misc_feature    complement(order(985959..985961,985971..985973,
                     986010..986012,986094..986096))
                     /locus_tag="Smed_4500"
                     /note="active site"
                     /db_xref="CDD:187644"
     gene            986674..988167
                     /locus_tag="Smed_4501"
                     /db_xref="GeneID:5317941"
     CDS             986674..988167
                     /locus_tag="Smed_4501"
                     /note="TIGRFAM: glycerol kinase;
                     PFAM: carbohydrate kinase FGGY;
                     KEGG: sme:SMb21009 probable glycerol kinase, similar to
                     sugar kinases protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="YP_001313234.1"
                     /db_xref="GI:150376638"
                     /db_xref="InterPro:IPR000577"
                     /db_xref="InterPro:IPR005999"
                     /db_xref="GeneID:5317941"
                     /translation="MGGYILAIDQGTTSTRAIVFDGNQKIAGIGQKEFKQHFPKSGWV
                     EHDPEEIWQTVLSTVREAIEKAGIGASDVAAIGITNQRETVVVWERDTGKPIHNAIVW
                     QDRRTAAFCDKLKKKGLEKTFVKKTGLLLDPYFSGTKLNWLLSNVKGAQARAASGELC
                     FGTIDTFLIWRLTQGKCFCTDATNASRTLIYNIAENAWDDELLRILRVPKQMLPEVKD
                     CAADFGITDPSLFGAAIPILGVAGDQQAATIGQACFKPGMLKSTYGTGCFALLNTGKD
                     MVRSKNRLLTTIAYRLDGETTYALEGSIFVAGAAVQWLRDGLKVIKAAPDTGSLAESA
                     DPSQEVYLVPAFTGLGAPHWDPDARGAIFGMTRNTGPAEFARAALEAVCYQTRDLLEA
                     MHKDWRRNGNDTVLRVDGGMVASDWTMQRLSDLLDAPVDRPMILETTALGVAWLAGSR
                     AGVWPNQEAFAKSWARDRRFEPQMDETTRKVKLKGWRSAIKRTLAAA"
     misc_feature    986674..988158
                     /locus_tag="Smed_4501"
                     /note="Glycerol kinase [Energy production and conversion];
                     Region: GlpK; COG0554"
                     /db_xref="CDD:223628"
     misc_feature    986683..988146
                     /locus_tag="Smed_4501"
                     /note="Escherichia coli glycerol kinase-like proteins;
                     belongs to the FGGY family of carbohydrate kinases;
                     Region: FGGY_EcGK_like; cd07786"
                     /db_xref="CDD:198361"
     misc_feature    order(986683..986688,986692..986694,986698..986700,
                     986707..986712,986719..986721,986725..986727,
                     986731..986736,986743..986745,986749..986751,
                     986797..986799,986893..986919,986977..986982,
                     986986..986988,986995..986997,987007..987009,
                     987043..987045,987052..987063,987067..987069,
                     987073..987078,987217..987222,987229..987234,
                     987250..987255,987259..987261,987325..987336,
                     987385..987390,987406..987411,987466..987468,
                     987475..987477,987502..987504,987508..987510,
                     987526..987546,987559..987561,987565..987567,
                     987574..987576,987580..987582,987586..987591,
                     987607..987609,987712..987714,987733..987735,
                     987739..987744,987748..987750,987982..987984,
                     987988..987996,988000..988005,988009..988026,
                     988030..988035)
                     /locus_tag="Smed_4501"
                     /note="N- and C-terminal domain interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:198361"
     misc_feature    order(986698..986700,986704..986712,986719..986721,
                     986914..986922,986977..986979,987073..987075,
                     987400..987405,987460..987468,987475..987477,
                     987595..987600,987604..987609,987643..987648,
                     987652..987654,987901..987909,987916..987918)
                     /locus_tag="Smed_4501"
                     /note="active site"
                     /db_xref="CDD:198361"
     misc_feature    order(986698..986700,986704..986712,986719..986721,
                     987460..987468,987595..987600,987604..987609,
                     987643..987648,987652..987654,987901..987909,
                     987916..987918)
                     /locus_tag="Smed_4501"
                     /note="MgATP binding site [chemical binding]; other site"
                     /db_xref="CDD:198361"
     misc_feature    order(986698..986700,986707..986709,987400..987402)
                     /locus_tag="Smed_4501"
                     /note="catalytic site [active]"
                     /db_xref="CDD:198361"
     misc_feature    order(986698..986700,987400..987402)
                     /locus_tag="Smed_4501"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:198361"
     misc_feature    order(986707..986709,986914..986922,986977..986979,
                     987073..987075,987400..987405,987475..987477)
                     /locus_tag="Smed_4501"
                     /note="glycerol binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:198361"
     misc_feature    order(986767..986769,986818..986820,986827..986832,
                     986842..986844,986851..986856,986953..986955,
                     987184..987186,987193..987195,987352..987357)
                     /locus_tag="Smed_4501"
                     /note="homotetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:198361"
     misc_feature    order(986785..986787,986794..986796,986803..986805,
                     986980..986982,987589..987591,987598..987600,
                     987607..987612,987619..987621,987688..987690,
                     987694..987696,987709..987711,987748..987774,
                     987784..987786,987793..987795)
                     /locus_tag="Smed_4501"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:198361"
     misc_feature    order(987364..987369,987373..987375)
                     /locus_tag="Smed_4501"
                     /note="FBP binding site [chemical binding]; other site"
                     /db_xref="CDD:198361"
     misc_feature    order(987877..987879,987883..987885,988087..988089,
                     988093..988095,988099..988110,988114..988116)
                     /locus_tag="Smed_4501"
                     /note="protein IIAGlc interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:198361"
     gene            988339..988662
                     /locus_tag="Smed_4502"
                     /db_xref="GeneID:5317942"
     CDS             988339..988662
                     /locus_tag="Smed_4502"
                     /note="PFAM: regulatory protein ArsR;
                     KEGG: sme:SMb21008 putative transcriptional regulator,
                     ArsR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein ArsR"
                     /protein_id="YP_001313235.1"
                     /db_xref="GI:150376639"
                     /db_xref="InterPro:IPR001845"
                     /db_xref="GeneID:5317942"
                     /translation="MSDAYDMLFRTLSDPTRRALFERLCREGERTVGALTDKAGVSQP
                     VVSKHLGLLKQAGLVRDRHEGRHTYYSAQLGALAPLVDWTREMAGFWQSRFDDLEDLL
                     KRMDQ"
     misc_feature    988363..>988554
                     /locus_tag="Smed_4502"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cd00090"
                     /db_xref="CDD:238042"
     misc_feature    order(988363..988368,988372..988374,988381..988383,
                     988390..988395,988402..988407,988417..988419,
                     988507..988509)
                     /locus_tag="Smed_4502"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    order(988366..988371,988381..988389,988429..988437,
                     988462..988473,988477..988482,988489..988494,
                     988498..988503,988519..988527,988540..988548)
                     /locus_tag="Smed_4502"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238042"
     misc_feature    order(988429..988431,988438..988440)
                     /locus_tag="Smed_4502"
                     /note="putative Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238042"
     gene            988659..989090
                     /locus_tag="Smed_4503"
                     /db_xref="GeneID:5317943"
     CDS             988659..989090
                     /locus_tag="Smed_4503"
                     /note="PFAM: Activator of Hsp90 ATPase 1 family protein;
                     KEGG: sme:SMb21007 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="activator of Hsp90 ATPase 1 family protein"
                     /protein_id="YP_001313236.1"
                     /db_xref="GI:150376640"
                     /db_xref="InterPro:IPR013538"
                     /db_xref="GeneID:5317943"
                     /translation="MNETSTETRSVVVEREIAHPPEKIWRALTQPHLMEEWLMKNDFS
                     AVVGHRFNLRGEWGGVLDCEVLVVEPNKKLSYAWNFAHEDPAYDLKSVVTFTLVPTRS
                     GTQLRMEQVGFRPDQRQAFGGAKAGWQQFFENLERVLAGMN"
     misc_feature    988686..989081
                     /locus_tag="Smed_4503"
                     /note="Putative hydrophobic ligand-binding SRPBCC domain
                     of Micromonospora echinospora CalC, human Aha1, and
                     related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814"
                     /db_xref="CDD:176856"
     misc_feature    order(988689..988691,988695..988697,988701..988703,
                     988728..988736,988740..988745,988758..988760,
                     988776..988778,988800..988802,988806..988808,
                     988812..988814,988818..988820,988836..988838,
                     988842..988847,988851..988853,988860..988862,
                     988878..988880,988884..988889,988932..988937,
                     988941..988943,988947..988949,988977..988979,
                     988983..988985,988989..988991,988995..988997,
                     989016..989042,989046..989054,989061..989063)
                     /locus_tag="Smed_4503"
                     /note="putative hydrophobic ligand binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:176856"
     gene            989154..989372
                     /locus_tag="Smed_4504"
                     /db_xref="GeneID:5317944"
     CDS             989154..989372
                     /locus_tag="Smed_4504"
                     /note="KEGG: mes:Meso_0629 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313237.1"
                     /db_xref="GI:150376641"
                     /db_xref="InterPro:IPR010916"
                     /db_xref="GeneID:5317944"
                     /translation="MNRSAWIRQIHRWLSIVFTVTVMANFSAMALGEPPVWVVYSPLL
                     PLFLLLFTGLYMFALPYSAKWRGGRPTA"
     sig_peptide     989154..989246
                     /locus_tag="Smed_4504"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.998) with cleavage site probability 0.712 at
                     residue 31"
     gene            989386..989844
                     /locus_tag="Smed_4505"
                     /db_xref="GeneID:5317945"
     CDS             989386..989844
                     /locus_tag="Smed_4505"
                     /note="PFAM: Domain of unknown function DUF1801;
                     KEGG: sme:SMb21005 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313238.1"
                     /db_xref="GI:150376642"
                     /db_xref="InterPro:IPR014922"
                     /db_xref="GeneID:5317945"
                     /translation="MASKTPGKTERAAKRDSSDGKPVLLSGGNPQIAKGYGDAPVKAY
                     IAAMPDWKKDLGRRLDALIVDAVPNVCKAIKWNSPFYGMENDVWFLSFHCFTKYVKVT
                     FFRGASLNPVPPGKSKYPEVRYLDIHEGQLDEGQFSAWVRQASRLPGERM"
     misc_feature    989455..989841
                     /locus_tag="Smed_4505"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG5649"
                     /db_xref="CDD:227936"
     gene            989890..990315
                     /locus_tag="Smed_4506"
                     /db_xref="GeneID:5317946"
     CDS             989890..990315
                     /locus_tag="Smed_4506"
                     /note="PFAM: Domain of unknown function DUF1801;
                     KEGG: rle:RL2762 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313239.1"
                     /db_xref="GI:150376643"
                     /db_xref="InterPro:IPR014922"
                     /db_xref="GeneID:5317946"
                     /translation="MSGPNEGDVSPSQLIDARISEFSDWRGETLARIRKLIRRADPEV
                     IEEVKWRGVPVWSHAGMICTGEVYKNAVKTTFAKGASLDDPSGLFNSSLKGNTRRAID
                     FHEGEEIDEEAFIALVRAAVALNMSARTSARSQKKPKST"
     misc_feature    989917..990276
                     /locus_tag="Smed_4506"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG5649"
                     /db_xref="CDD:227936"
     gene            990423..991466
                     /locus_tag="Smed_4507"
                     /db_xref="GeneID:5317947"
     CDS             990423..991466
                     /locus_tag="Smed_4507"
                     /note="PFAM: luciferase family protein;
                     KEGG: sme:SMb21003 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="luciferase family protein"
                     /protein_id="YP_001313240.1"
                     /db_xref="GI:150376644"
                     /db_xref="InterPro:IPR011251"
                     /db_xref="GeneID:5317947"
                     /translation="MELGLYTFADVDPNAADKGAEARRRLTNLLEEIELADQVGLDVF
                     GLGEHHRPDYAASAPAVILAAAAARTSRIRLTSAVTVLSSDEPVRVFQQFATLDVLSN
                     GRAEIMAGRGSFIESFPLFGQSLDDYDQLFAEKLDLLLALRDNERVTWSGALRAPIDD
                     RGVYPRPLQDPLPLWIAVGGTPQSVARAGALGLPMALAIIGGEPERFAPLFQLYREAA
                     RRSGQDPSKLKSSINVHGFIADTTQEAADQFYGPQAEVMNRIGRERGWGPTNRTHFDR
                     AISPTGNLFLGDPETVARKIVAHQKLFDIDRFLLQMAIGPMPHDRILRGIELYGTKVA
                     PLVREMLAEQHSS"
     misc_feature    990477..991433
                     /locus_tag="Smed_4507"
                     /note="Coenzyme F420-dependent N5,N10-methylene
                     tetrahydromethanopterin reductase and related
                     flavin-dependent oxidoreductases [Energy production and
                     conversion]; Region: COG2141"
                     /db_xref="CDD:225052"
     misc_feature    <990936..991088
                     /locus_tag="Smed_4507"
                     /note="Flavin-utilizing monoxygenases; Region:
                     Flavin_utilizing_monoxygenases; cd00347"
                     /db_xref="CDD:238209"
     gene            991539..992288
                     /locus_tag="Smed_4508"
                     /db_xref="GeneID:5318071"
     CDS             991539..992288
                     /locus_tag="Smed_4508"
                     /EC_number="3.4.11.18"
                     /note="catalyzes the removal of N-terminal amino acids
                     from peptides and arylamides; generally Co(II) however
                     activity has been shown for some methionine
                     aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the
                     protein in this cluster is considered non-essential"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine aminopeptidase"
                     /protein_id="YP_001313241.1"
                     /db_xref="GI:150376645"
                     /db_xref="InterPro:IPR000994"
                     /db_xref="InterPro:IPR001714"
                     /db_xref="InterPro:IPR002467"
                     /db_xref="GeneID:5318071"
                     /translation="MTLNNDDDLERLKEIGRICANALQTMGEALEPGITTAELDAIGR
                     KVMEEAGARSAPELCYAFPGATCISVNEEIAHGIPGSRVIQAGDLVNIDVSAEKGGLF
                     ADTGASFPVPPVTAAIDRLCRDGKRAMWVGLKQVKPGQPLAAIGNSIGAFARKNRYSL
                     VANLASHGIGRSLHEEPSEIATWPDPSERRRMAEGMVFTVEPFLSMGAQWAEGGDDDW
                     TLYSEPRAPTVQYEHTVVVTRSGPLVVTLPG"
     misc_feature    991563..992279
                     /locus_tag="Smed_4508"
                     /note="Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also
                     known as methionyl aminopeptidase and Peptidase M.
                     Catalyzes release of N-terminal amino acids,
                     preferentially methionine, from peptides and arylamides;
                     Region: MetAP1; cd01086"
                     /db_xref="CDD:238519"
     misc_feature    order(991764..991766,991815..991817,991848..991850,
                     992037..992039,992139..992141,992232..992234)
                     /locus_tag="Smed_4508"
                     /note="active site"
                     /db_xref="CDD:238519"
     gene            992444..993622
                     /locus_tag="Smed_4509"
                     /db_xref="GeneID:5318072"
     CDS             992444..993622
                     /locus_tag="Smed_4509"
                     /note="PFAM: protein of unknown function DUF1228; major
                     facilitator superfamily MFS_1;
                     KEGG: sme:SMb21000 putative transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313242.1"
                     /db_xref="GI:150376646"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR010645"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5318072"
                     /translation="MPSGLAATAIAGAIAMAVAMGFGRFSYTPILPAMMADTGISPGD
                     AGLIAAANFIGYLAGAVLAGYGWAHGRERGLGLAALVSTTLLLAAMGLTSSVIAFCII
                     RFLAGLASAFAMIFISGIVLGQGLAARSEHVPSVHFGGVGFGIALSSIVVWVAPLAGA
                     AGISASQADWFAGGLVALVGAVAVAALLPASRHAKSGGRPEARLVATRPLIAVTLTYG
                     FFGFGYVITATFLVAMARDASGGHSVEFLAWLITGISAALSIYLWRFAVPHFGLAGVY
                     AAGLLVEAAGLVLTVSLPSPYAPLVGGLMLGATFMMITAYGLQMGRQLAPESPRRALA
                     FMTAAFGLGQIVGPLVAGWLADRTGSYALPTLVAAVVLLICGIVVLAELRRINAALAQ
                     "
     sig_peptide     992444..992503
                     /locus_tag="Smed_4509"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.994) with cleavage site probability 0.570 at
                     residue 20"
     misc_feature    992507..992746
                     /locus_tag="Smed_4509"
                     /note="Protein of unknown function (DUF1228); Region:
                     DUF1228; pfam06779"
                     /db_xref="CDD:219173"
     gene            993776..995038
                     /locus_tag="Smed_4510"
                     /db_xref="GeneID:5318073"
     CDS             993776..995038
                     /locus_tag="Smed_4510"
                     /note="in Escherichia coli SbmA is involved in uptake of
                     microcin J25; functions along with FhuA, TonB, and ExbB/D
                     in this capacity; in Sinorhizobium meliloti, BacA is
                     essential and required for symbiosis; defects appear to
                     affect the cell envelope"
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="YP_001313243.1"
                     /db_xref="GI:150376647"
                     /db_xref="InterPro:IPR009248"
                     /db_xref="InterPro:IPR010509"
                     /db_xref="GeneID:5318073"
                     /translation="MFQSFFPKPKLFFISSAVWSLLAVLAWYGGGRDIGAYLGLPPLP
                     PGQEPIIGVSVFWSTPFLWFYVYYAVVVALFSAFWFAYSPHRWQYWSVLGTALIIFNT
                     YFSVQVSVAINAWYGPFYDLIQQALARTAPVTAGQLYSGMVGFAGIAFVAVTVGVLNL
                     FFVSHYIFRWRTAMNEYYVTHWPRLRHVEGASQRVQEDTMRFSSTVERLGVGLVSSIM
                     TLIAFLPVLFKFSEQVNVLPIVGEIPHALVWAAVFWSVFGTVFLAAVGIKLPGLEFRN
                     QRVEAAYRKELVYGEDHEDRADPVTLGQLFDNVRRNYFRLYFHYMYFNIARIFYLQAD
                     NLFGTFVLVPAIVAGKLTLGVMNQVLNVFEQVRTSFQYLVNSWTTIVELLSIYKRLKA
                     FESVLDDEPLPEIDRQFIDAGGKEELAL"
     misc_feature    993776..995005
                     /locus_tag="Smed_4510"
                     /note="microcin B17 transporter; Reviewed; Region:
                     PRK11098"
                     /db_xref="CDD:182960"
     sig_peptide     993776..993856
                     /locus_tag="Smed_4510"
                     /product="transport protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.882) with cleavage site probability 0.464 at
                     residue 27"
     gene            complement(995048..996046)
                     /locus_tag="Smed_4511"
                     /db_xref="GeneID:5318074"
     CDS             complement(995048..996046)
                     /locus_tag="Smed_4511"
                     /note="KEGG: sme:SMb20998 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313244.1"
                     /db_xref="GI:150376648"
                     /db_xref="GeneID:5318074"
                     /translation="MIRISLALSVALFPALALADPPSARQLPKQLVVISFDGAHDNAL
                     WQKSLTMGKRTGARFTYFLSCTFLMTRADGKQTYRAPGQKPGRSNVGFAQSREDIAMR
                     AGHVWQAHLAGHEIGSHACGHFDGKDWSKADWASEFSAFRAALANAWKRAGKPEAEPE
                     GWADFAQGGIKGFRAPYLSLSDGLVPALKTFGFSYDASLVTKGPGWPSFADGLIRFGL
                     PLIPEGPSHRPVIGMDYNLFVRHSMGVENSRDSARFEERTLAAFRNAFRKEYEGERIP
                     LQLGFHFVEMNGGAYWRALDGFLSETCSKPDVACVSYAEALPLIENARKKADRSAF"
     sig_peptide     complement(995987..996046)
                     /locus_tag="Smed_4511"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.998 at
                     residue 20"
     misc_feature    complement(995072..995965)
                     /locus_tag="Smed_4511"
                     /note="Putative catalytic domain of uncharacterized
                     bacterial hypothetical proteins similar to insect chitin
                     deacetylase-like proteins; Region: CE4_CDA_like_3;
                     cd10976"
                     /db_xref="CDD:200598"
     misc_feature    complement(order(995201..995203,995207..995209,
                     995450..995452,995519..995521,995525..995527,
                     995675..995692,995933..995944))
                     /locus_tag="Smed_4511"
                     /note="NodB motif; other site"
                     /db_xref="CDD:200598"
     misc_feature    complement(order(995201..995203,995513..995521,
                     995678..995680,995690..995692,995933..995938))
                     /locus_tag="Smed_4511"
                     /note="putative active site [active]"
                     /db_xref="CDD:200598"
     misc_feature    complement(order(995201..995203,995936..995938))
                     /locus_tag="Smed_4511"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:200598"
     gene            996217..996804
                     /locus_tag="Smed_4512"
                     /db_xref="GeneID:5318075"
     CDS             996217..996804
                     /locus_tag="Smed_4512"
                     /note="PFAM: NnrUfamily protein;
                     KEGG: sme:SMb20997 putative membrane protein, similar to
                     periplasmic nitrate reductase NnuR"
                     /codon_start=1
                     /transl_table=11
                     /product="NnrU family protein"
                     /protein_id="YP_001313245.1"
                     /db_xref="GI:150376649"
                     /db_xref="InterPro:IPR009915"
                     /db_xref="GeneID:5318075"
                     /translation="MAILLLGIIIFLGMHLIRVVAPGFRAGIIESRGKGTWMGLYTIV
                     SLVGVCLIIYGFGQARGETGVLYNPPEFLRHIALLLMLIAFIVLAAGFLPAGRIAVAL
                     KHPQVLSIKIWALAHLLANGETSSVLLFGSFLAWAVILRISLKRRERAGEKVLPVFKS
                     GRNDVLAVLTGLAAYVLFVWKLHELVIGVPPVVIG"
     misc_feature    996268..996795
                     /locus_tag="Smed_4512"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG4094"
                     /db_xref="CDD:226579"
     gene            996939..997607
                     /locus_tag="Smed_4513"
                     /db_xref="GeneID:5318076"
     CDS             996939..997607
                     /locus_tag="Smed_4513"
                     /note="KEGG: sme:SMb20996 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313246.1"
                     /db_xref="GI:150376650"
                     /db_xref="GeneID:5318076"
                     /translation="MVNQDDSFIREVNDELRSDQMKAVWTRFGSIIIGIAVLIVLGTV
                     GKVGYDYWQESSSSQSGDTFLVALNLARENKSDEALAALTGLEKEGYGSYPVLAQLRL
                     ATLQAQKGETDAAVKAFSGIGRDTRIPTALRDAARLRAAYLLIDAGTYEQVSSEVEQL
                     AVPQNAMRHSAREALGLSAYKAGDYAKAKSWFQQIVDDTESPRGVMNRAQMLLDVIAS
                     SGKA"
     misc_feature    996945..997604
                     /locus_tag="Smed_4513"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4649"
                     /db_xref="CDD:226996"
     gene            997718..999151
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /db_xref="GeneID:5318077"
     CDS             997718..999151
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="EngA; essential Neisserial GTPase; synchronizes
                     cellular events by interacting with multiple targets with
                     tandem G-domains; overexpression in Escherichia coli
                     suppresses rrmJ mutation; structural analysis of the
                     Thermotoga maritima ortholog shows different nucleotide
                     binding affinities in the two binding domains"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein EngA"
                     /protein_id="YP_001313247.1"
                     /db_xref="GI:150376651"
                     /db_xref="InterPro:IPR001806"
                     /db_xref="InterPro:IPR002917"
                     /db_xref="InterPro:IPR005225"
                     /db_xref="InterPro:IPR005289"
                     /db_xref="InterPro:IPR006073"
                     /db_xref="InterPro:IPR013684"
                     /db_xref="GeneID:5318077"
                     /translation="MSFTVAIIGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGD
                     AKLVDLKFRIIDTAGLEQSSPDSLQGRMWAQTEAAIDEADLSLFVVDAKAGLTPADKT
                     LGEMLRRRGKPVVVVANKSEARGSEGGFYDAFTLGLGEPCPISAEHGQGMLDLRDAIV
                     AALGEERAFPPAEDVAETNVDIRADIGSEGPGEEEIEPVYDETKPLRVAIVGRPNAGK
                     STLINRFLGEDRLLTGPEAGITRDSISVEWDWRGRTIKMFDTAGMRRKAKVQEKLEKL
                     SVADALRAIRFAETVVIVFDATIPFEKQDLQIVDLVIREGRAAVLAFNKWDLVENWQE
                     LLADLREKTERLLPQARGIRAVPISGHTGYGLDRLMQAIIETDKVWNRRISTARLNRW
                     LESQQVQHPPPAVSGRRLKLKYMTQVKARPPGFMISCTRPEAVPESYTRYLINGLRND
                     FDLAGVPIRIHFRASENPYESKARKKR"
     misc_feature    997721..999118
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="GTP-binding protein Der; Reviewed; Region:
                     PRK00093"
                     /db_xref="CDD:234628"
     misc_feature    997733..998206
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="EngA1 GTPase contains the first domain of EngA;
                     Region: EngA1; cd01894"
                     /db_xref="CDD:206681"
     misc_feature    997742..997765
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="G1 box; other site"
                     /db_xref="CDD:206681"
     misc_feature    order(997751..997753,997757..997768,998072..998077,
                     998081..998083,998150..998158)
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206681"
     misc_feature    order(997796..997816,997826..997837)
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206681"
     misc_feature    997826..997828
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="G2 box; other site"
                     /db_xref="CDD:206681"
     misc_feature    order(997880..997897,997961..997966)
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206681"
     misc_feature    997883..997894
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="G3 box; other site"
                     /db_xref="CDD:206681"
     misc_feature    998072..998083
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="G4 box; other site"
                     /db_xref="CDD:206681"
     misc_feature    998150..998158
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="G5 box; other site"
                     /db_xref="CDD:206681"
     misc_feature    998327..998845
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="EngA2 GTPase contains the second domain of EngA;
                     Region: EngA2; cd01895"
                     /db_xref="CDD:206682"
     misc_feature    998351..998374
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="G1 box; other site"
                     /db_xref="CDD:206682"
     misc_feature    order(998360..998362,998366..998377,998687..998692,
                     998696..998698,998792..998800)
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206682"
     misc_feature    order(998396..998398,998405..998446)
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206682"
     misc_feature    998435..998437
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="G2 box; other site"
                     /db_xref="CDD:206682"
     misc_feature    998492..998503
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="G3 box; other site"
                     /db_xref="CDD:206682"
     misc_feature    order(998501..998506,998576..998581)
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206682"
     misc_feature    998687..998698
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="G4 box; other site"
                     /db_xref="CDD:206682"
     misc_feature    998792..998800
                     /gene="engA"
                     /locus_tag="Smed_4514"
                     /gene_synonym="yfgK; yphC"
                     /note="G5 box; other site"
                     /db_xref="CDD:206682"
     gene            999391..999930
                     /locus_tag="Smed_4515"
                     /db_xref="GeneID:5318078"
     CDS             999391..999930
                     /locus_tag="Smed_4515"
                     /note="TIGRFAM: putative transcriptional regulator, Rrf2
                     family;
                     PFAM: protein of unknown function UPF0074;
                     KEGG: sme:SMb20994 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="BadM/Rrf2 family transcriptional regulator"
                     /protein_id="YP_001313248.1"
                     /db_xref="GI:150376652"
                     /db_xref="InterPro:IPR000944"
                     /db_xref="GeneID:5318078"
                     /translation="MCPGHRDADRVHVSFAAILLESGVLMLTKKGKYGLKAMVDLAQL
                     QPGETAFITEIALRNNLPKKFLDTIMLELRNAGFLRSKKGPGGGYALARPASEIRVGQ
                     VIRTLDGPLAPIRCASRTAYEMCDDCSDPENCHVRRSMIVVRDAVANILDNMTLAQFA
                     ASEKDAADVVLAPLRSEAG"
     misc_feature    999466..999861
                     /locus_tag="Smed_4515"
                     /note="Rrf2 family protein; Region: rrf2_super; TIGR00738"
                     /db_xref="CDD:129821"
     misc_feature    999469..999711
                     /locus_tag="Smed_4515"
                     /note="Transcriptional regulator; Region: Rrf2; pfam02082"
                     /db_xref="CDD:202106"
     gene            complement(999986..1001173)
                     /locus_tag="Smed_4516"
                     /db_xref="GeneID:5318079"
     CDS             complement(999986..1001173)
                     /locus_tag="Smed_4516"
                     /note="PFAM: acyl-CoA dehydrogenase domain protein;
                     Acyl-CoA dehydrogenase type 2 domain;
                     KEGG: sme:SMb20993 putative FMNH2-dependent monooxygenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase type 2"
                     /protein_id="YP_001313249.1"
                     /db_xref="GI:150376653"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR013107"
                     /db_xref="GeneID:5318079"
                     /translation="MGSISQFAGKTRPAPRHIESEEEALTVAKDLAFRFAERASERDL
                     ERILPHDELDQLAQSGLLAISIPSEYEGIDVSNVVLAEVTAILSEADSSIGQIPQGHF
                     HALEALRQYATEEQKQFFFGRARAGDRFSSAISESSEKTIGSPITRIIGDGAGYRING
                     RKEYLTGILFADWIAISALDATELMTLSFVPRTTEGVRIIDDWDSFGQRVNGSGTAIL
                     ENIHVDRSSVVPYHRAFGRQTTIGSVGQIINAGVDLGIARAAFRETLEYVRNGADSSE
                     DALAIAKIGEVAIRLEAATALIEYAGLKVDTAQVDPTEAHAAEASITVTAAKVLAAEA
                     ALEASNTLFDLAGAASTKVSQNLDRYWRNARAHASQDPLRRKHHLVGNYHLNGVRPRD
                     GSL"
     misc_feature    complement(1000004..1001131)
                     /locus_tag="Smed_4516"
                     /note="sulfur acquisition oxidoreductase, SfnB family;
                     Region: sulfur_SfnB; TIGR04022"
                     /db_xref="CDD:188537"
     misc_feature    complement(1000004..1001098)
                     /locus_tag="Smed_4516"
                     /note="Acyl-CoA dehydrogenase; Region: ACAD; cl09933"
                     /db_xref="CDD:245208"
     misc_feature    complement(order(1000037..1000039,1000043..1000045,
                     1000049..1000057,1000676..1000678,1000682..1000684,
                     1000772..1000774,1000778..1000780,1000865..1000867))
                     /locus_tag="Smed_4516"
                     /note="active site"
                     /db_xref="CDD:173838"
     gene            1001730..1003130
                     /locus_tag="Smed_4517"
                     /db_xref="GeneID:5318080"
     CDS             1001730..1003130
                     /locus_tag="Smed_4517"
                     /note="similar to Y20991; KEGG: sme:SMb20992 conserved
                     hypothetical protein, similar to Y20991"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313250.1"
                     /db_xref="GI:150376654"
                     /db_xref="GeneID:5318080"
                     /translation="MTVRGLFARRSAMAALSKPEIAIVGRGFSGIMMAIALMKSMRVS
                     FHLTMYDPHPSISGGQVFSAAQRCEILNSRVRDLSVAAGQPDDFNDWLCANDEFRTAV
                     PAAIPGFRQIFVPKGIFSDYVHQRFSEALARRSDITVRFSHEPVTGLRKLASGRFSLV
                     RHGGNDESDIVILATGFGMRPRDLEVSEEERPLVRTRRLVDPRHAVLLGSGIRVVDQL
                     FQMRDNGYAGKVTLISRHGFLPQAHTQRAASPSFPVDPLPQGLGRIVRFVRQACAEAE
                     ANGQGWQSAMNGLRRRARSLWQSLSAQEKRQFNRHLRAIYDSHRNRLPAAVHARLQQE
                     LGEGRTVLRRGRAGRRLPEGILVRWAGQDTEELLRADQVIECRCSAPDLGTPLLRSLI
                     AGGLAQPDELELGIAVAPTGEVLSSSGHTPNLFAIGPLGLGSLPDIDLVPEIVTQTYA
                     ASRLIATGKRMTLKAG"
     misc_feature    1001781..1003127
                     /locus_tag="Smed_4517"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4529"
                     /db_xref="CDD:226906"
     misc_feature    1001793..1002263
                     /locus_tag="Smed_4517"
                     /note="FAD-NAD(P)-binding; Region: NAD_binding_9;
                     pfam13454"
                     /db_xref="CDD:222141"
     gene            1003250..1004707
                     /locus_tag="Smed_4518"
                     /db_xref="GeneID:5318493"
     CDS             1003250..1004707
                     /locus_tag="Smed_4518"
                     /note="PFAM: FAD dependent oxidoreductase;
                     KEGG: sme:SMb20991 conserved hypothetical protein, similar
                     to Y20992, slightly similar to monooxygenase"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD dependent oxidoreductase"
                     /protein_id="YP_001313251.1"
                     /db_xref="GI:150376655"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="GeneID:5318493"
                     /translation="MMDSFGQNAPRPTVAIIGGGFTGAMVAMHLARDRAMDGWQIAVF
                     EPRVRLGCGLAYDTAEPAHRVNVPAARMSIDPDDPDDFARWLALQSELRDDPEVLAGD
                     GHLYPRRQLFGRYVAEAVVPFVRSGRIVHHRERVIAVEREGAAWAVRGEGGTLNRADA
                     LVVATTHPAPEAPAGFGAVLTGHPRYVPDSTEPGALDKIRTDDRVLIIGTGLTSADVI
                     ATLRTRGHKGPITAFSRRGLRSRGHADRAQDPFGDFVAPPWRSAAELLAQVRRTISDA
                     EAEGFTWHAVLDALRAQGGEIWRNLPVDERRRLVRHARPFWDVHRFRVAPQIDAIVST
                     GLKDGDIRVRAGSIAHLARAGENVAVTFRGRRAGGTEEWKFDAVVITTGPAHRSILQS
                     QPWLESLGAAGYLRPDTVGLGLACSEASRALDGEGEEVDDLFVAGPLARGTFGELMGL
                     PQVNDHAIFVAAQIAALAQARRAESVRSRREEAAT"
     misc_feature    1003280..1004617
                     /locus_tag="Smed_4518"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4529"
                     /db_xref="CDD:226906"
     misc_feature    1003292..1003753
                     /locus_tag="Smed_4518"
                     /note="FAD-NAD(P)-binding; Region: NAD_binding_9;
                     pfam13454"
                     /db_xref="CDD:222141"
     misc_feature    <1003637..1003966
                     /locus_tag="Smed_4518"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; cl17500"
                     /db_xref="CDD:248054"
     gene            1004915..1006273
                     /locus_tag="Smed_4519"
                     /db_xref="GeneID:5318494"
     CDS             1004915..1006273
                     /locus_tag="Smed_4519"
                     /note="PFAM: protein of unknown function DUF107;
                     KEGG: sme:SMb20990 probable membrane protein necessary for
                     nodulation competitiveness"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313252.1"
                     /db_xref="GI:150376656"
                     /db_xref="InterPro:IPR002810"
                     /db_xref="GeneID:5318494"
                     /translation="MARILFLLFSLLSAFMLPVSPAPAAERKAIVLHVNGAISPATAE
                     YVTRGLRRARDRGVALVVLQMDTPGGLDTSMREIIRAILDSPVPVASFVAPSGARAAS
                     AGTYILYASHIAAMAPGTNLGAATPIAIGGGLFGDDERDGEETPGEPDKQEPRKPADA
                     GEAKLINDAIAYIRGLAELRGRNIDWAERAVREAASLSSAAAAREQVIDFTAINLNDL
                     LKQAHGRSVRIGQSDVRLDTAGLFIEDLPPDWRTQLLSVITNPNVALLLMMVGIYGLI
                     FEFLSPGTVVPGTIGGISLLLGLYALAVLPVSYAGVALILLGAGLLVAEAHAPSFGVL
                     GLGSAVALVLGAAILFDTDVPGLQVSWPVLSGIGFASLAFGLLVARLALLSSRHKILT
                     GAEEMIGISGKVDSWEGAGGYVIAHGERWSAVSNEPLGPGEDVMVVGRQSLTLEVARK
                     PT"
     sig_peptide     1004915..1004992
                     /locus_tag="Smed_4519"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.993) with cleavage site probability 0.911 at
                     residue 26"
     misc_feature    1004969..1006264
                     /locus_tag="Smed_4519"
                     /note="Membrane-bound serine protease (ClpP class)
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: NfeD; COG1030"
                     /db_xref="CDD:223961"
     misc_feature    1004999..1005622
                     /locus_tag="Smed_4519"
                     /note="Nodulation formation efficiency D (NfeD) is a
                     membrane-bound ClpP-class protease; Region:
                     Clp_protease_NfeD_1; cd07020"
                     /db_xref="CDD:132931"
     misc_feature    order(1005002..1005004,1005560..1005562)
                     /locus_tag="Smed_4519"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132931"
     misc_feature    order(1005218..1005220,1005404..1005406)
                     /locus_tag="Smed_4519"
                     /note="active site residues [active]"
                     /db_xref="CDD:132931"
     misc_feature    <1005956..1006264
                     /locus_tag="Smed_4519"
                     /note="NfeD-like C-terminal, partner-binding; Region:
                     NfeD; pfam01957"
                     /db_xref="CDD:216808"
     gene            1006356..1007126
                     /locus_tag="Smed_4520"
                     /db_xref="GeneID:5318495"
     CDS             1006356..1007126
                     /locus_tag="Smed_4520"
                     /note="PFAM: band 7 protein;
                     KEGG: sme:SMb20989 putative stomatin-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313253.1"
                     /db_xref="GI:150376657"
                     /db_xref="InterPro:IPR001107"
                     /db_xref="InterPro:IPR001972"
                     /db_xref="GeneID:5318495"
                     /translation="MTWLGNLAPFAAALLFLLIIVAYAIRILREYERGVIFTLGRFTG
                     VKGPGLILILPYVQQMVRVDLRTRVLDVPSQDVISRDNVSVRVSAVIYFRVIDAEKST
                     IQVEDFMTATSQLAQTTLRSVLGKHDLDEMLAERDRLNEDIQKILDVQTDAWGIKVAT
                     VEIKHVDINESMIRAIARQAEAERERRAKVINAEGEQQAATKLLEAAEILARKPQAMQ
                     LRYLSTLNVIAAEKNSTIIFPFPMEIADMLATKKEGSS"
     sig_peptide     1006356..1006430
                     /locus_tag="Smed_4520"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.790) with cleavage site probability 0.660 at
                     residue 25"
     misc_feature    1006431..1007069
                     /locus_tag="Smed_4520"
                     /note="Membrane protease subunits, stomatin/prohibitin
                     homologs [Posttranslational modification, protein
                     turnover, chaperones]; Region: HflC; COG0330"
                     /db_xref="CDD:223407"
     misc_feature    1006437..1007078
                     /locus_tag="Smed_4520"
                     /note="Band_7_stomatin_like: A subgroup of the band 7
                     domain of flotillin (reggie) like proteins similar to
                     stomatin and podicin (two lipid raft-associated integral
                     membrane proteins). Individual proteins of this band 7
                     domain family may cluster to form...; Region:
                     Band_7_stomatin_like; cd03403"
                     /db_xref="CDD:239497"
     gene            1007251..1007721
                     /locus_tag="Smed_4521"
                     /db_xref="GeneID:5318496"
     CDS             1007251..1007721
                     /locus_tag="Smed_4521"
                     /note="PFAM: NUDIX hydrolase;
                     KEGG: sme:SMb20988 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="YP_001313254.1"
                     /db_xref="GI:150376658"
                     /db_xref="InterPro:IPR000086"
                     /db_xref="GeneID:5318496"
                     /translation="MPKRSAGILLYRYEAGNLLVLLVHPGGPFWSNRDVGAWSIPKGE
                     YDAAEEPEAAARREFLEETGIAIGGPLEFLGEERQKSGKLVTAYAHESEFDVDSLRSN
                     VFETEWPPRSGQMQSFPEVDRAAWFTPAEARRRINASQRPFIDRLEALRSRRAP"
     misc_feature    1007251..1007703
                     /locus_tag="Smed_4521"
                     /note="Nudix hydrolase is a superfamily of enzymes found
                     in all three kingdoms of life, and it catalyzes the
                     hydrolysis of NUcleoside DIphosphates linked to other
                     moieties, X. Enzymes belonging to this superfamily require
                     a divalent cation, such as Mg2+ or Mn2+...; Region:
                     Nudix_Hydrolase; cl00447"
                     /db_xref="CDD:241868"
     misc_feature    order(1007377..1007385,1007413..1007439)
                     /locus_tag="Smed_4521"
                     /note="nudix motif; other site"
                     /db_xref="CDD:239217"
     gene            complement(1007760..1008920)
                     /locus_tag="Smed_4522"
                     /db_xref="GeneID:5318497"
     CDS             complement(1007760..1008920)
                     /locus_tag="Smed_4522"
                     /note="TIGRFAM: siroheme synthase;
                     PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin)
                     methyltransferase;
                     KEGG: sme:SMb20987 putative siroheme synthetase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="siroheme synthase"
                     /protein_id="YP_001313255.1"
                     /db_xref="GI:150376659"
                     /db_xref="InterPro:IPR000878"
                     /db_xref="InterPro:IPR003043"
                     /db_xref="InterPro:IPR006367"
                     /db_xref="GeneID:5318497"
                     /translation="MLASPSQQSERPAKRERVAALATLPLFWPLKSKRVLVAGGSDAA
                     AWKAELLSACGAEVHVYAPRAILSGLFLDVLARGAAHELGRFVHHDKAWHADAFRDAA
                     IAIADCDEQSEAEAFFHAARTAGVPVNVIDKPAFCEFQFGSIVNRSPVIVAISTDGAA
                     PILAQAIRRRIEALLPPALKHWASIAQAIRDRVNARLSPGAARRIFWERFVDRAFLGK
                     PEQGVEMRLMAEADRQVTRPSAIGRVTIVGAGPGDAELLTLKAVRALQAADVILFDEC
                     IQDEVLELARREARRVPVAGSDKDRSSSNAILVQGDIAALVRKGKNVVRLRSGNPMAV
                     DEEFAAFERLGLPVQIVPGVEAEAYRPDMGSDMGELAFSGRPVQPGLHTTNH"
     misc_feature    complement(1008228..1008851)
                     /locus_tag="Smed_4522"
                     /note="siroheme synthase, N-terminal domain; Region:
                     cysG_Nterm; TIGR01470"
                     /db_xref="CDD:130536"
     misc_feature    complement(1008492..1008845)
                     /locus_tag="Smed_4522"
                     /note="Putative NAD(P)-binding; Region: NAD_binding_7;
                     pfam13241"
                     /db_xref="CDD:222002"
     misc_feature    complement(1008213..1008392)
                     /locus_tag="Smed_4522"
                     /note="Sirohaem synthase dimerisation region; Region:
                     CysG_dimeriser; pfam10414"
                     /db_xref="CDD:204480"
     misc_feature    complement(<1007853..1008206)
                     /locus_tag="Smed_4522"
                     /note="Uroporphyrinogen-III methylase [Coenzyme
                     metabolism]; Region: CysG; COG0007"
                     /db_xref="CDD:223086"
     misc_feature    complement(order(1007859..1007876,1007904..1007909,
                     1007916..1007918,1007922..1007927,1008132..1008137,
                     1008141..1008152,1008168..1008170))
                     /locus_tag="Smed_4522"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:212499"
     gene            complement(1008892..1011549)
                     /locus_tag="Smed_4523"
                     /db_xref="GeneID:5318498"
     CDS             complement(1008892..1011549)
                     /locus_tag="Smed_4523"
                     /note="PFAM: molybdopterin oxidoreductase; molydopterin
                     dinucleotide-binding region; molybdopterin oxidoreductase
                     Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain
                     protein;
                     KEGG: sme:SMb20986 putative nitrate reductase, large
                     subunit protein"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin oxidoreductase"
                     /protein_id="YP_001313256.1"
                     /db_xref="GI:150376660"
                     /db_xref="InterPro:IPR006655"
                     /db_xref="InterPro:IPR006656"
                     /db_xref="InterPro:IPR006657"
                     /db_xref="InterPro:IPR006963"
                     /db_xref="InterPro:IPR007419"
                     /db_xref="GeneID:5318498"
                     /translation="MAHEVKTTCPYCGVGCGVIARLGDDGAVSVKGDPEHPANFGRLC
                     SKGSALAETLDLDGRLLHPEIGGRRAGWSEALDLVAERFSHAIAEHGPDSVAFYVSGQ
                     LLTEDYYIANKLMKGFIGSANIDTNSRLCMSSSVAGHRRAFGSDTVPGVYEDLELAEL
                     VVLTGSNLAWCHPVLYQRLSAAKANRPEMKIVVIDPRRTMTADIADMHLAISPDGDVA
                     LFNGLLAHLAASGVIDRNYVSKCTSGFDEAVAVASRLDLPAVSNATGLTQAQLRAFYR
                     LFETTENVVTCYSQGVNQSAAGTDKVNAIINCHLATGRIGRPGMGPFSLTGQPNAMGG
                     REVGGLANMLAAHMDIEKSLHRDQVRRFWGAPAVANKPGLKAVDMFRAVADGRIKALW
                     IMATNPVVSMPDADAVEAAIKACPFVVVSDIVRDTDTARHAHVLLPSLGWGEKDGTVT
                     NSERCISRQRAFLRGPGEARPDWWQLAEVGKRMGFAPAFAYNSQAEIFAEHAALSGFE
                     NNGRRDFDISAHAEIGGTAYDGLKPFQWPQTRGSTPQQRRFFADGRYFHPDGRARFVA
                     IEVPGPRRRDAAFPFTLNTGRVRDHWHTMTRTGRSARLSGHLAEPFVEIHPRDAQAIG
                     VSGADLVTLESPHGAAIVRALVTDRQAEGNLFVPMHWNDQFASRARIDALVAPITDPV
                     SGQPASKHMTVRAGRLAAAVYGFAVSAHKPAELDAAYWAIARAEGGWRMELAFAEKEI
                     DWTDWCRKTFGIASEIEPIGYTDRTSGELRLAFFEEDRLLATLFLSPQPVAVARNWAV
                     SQLRASHHNLGKRFAVVAGRPGADTPDPGATVCSCFSVGVNQITAAVRVGCHSVEAVG
                     EKLSAGTNCGSCRAEIRGIINACLTVAAE"
     misc_feature    complement(1009468..1011549)
                     /locus_tag="Smed_4523"
                     /note="Anaerobic dehydrogenases, typically
                     selenocysteine-containing [Energy production and
                     conversion]; Region: BisC; COG0243"
                     /db_xref="CDD:223321"
     misc_feature    complement(1009834..1011534)
                     /locus_tag="Smed_4523"
                     /note="Nitrate reductases, NapA (Nitrate-R-NapA), NasA,
                     and NarB catalyze the reduction of nitrate to nitrite.
                     Monomeric Nas is located in the cytoplasm and participates
                     in nitrogen assimilation. Dimeric Nap is located in the
                     periplasm and is coupled to quinol...; Region:
                     MopB_Nitrate-R-NapA-like; cd02754"
                     /db_xref="CDD:239155"
     misc_feature    complement(order(1011028..1011030,1011418..1011420,
                     1011502..1011504,1011514..1011519,1011523..1011525))
                     /locus_tag="Smed_4523"
                     /note="[4Fe-4S] binding site [ion binding]; other site"
                     /db_xref="CDD:239155"
     misc_feature    complement(order(1010134..1010136,1010215..1010217,
                     1010227..1010235,1010278..1010289,1010347..1010349,
                     1010359..1010364,1010566..1010571,1010668..1010670,
                     1010677..1010685,1010902..1010904,1010908..1010910,
                     1010959..1010967,1011037..1011042,1011049..1011060,
                     1011157..1011159,1011169..1011171,1011244..1011246,
                     1011412..1011414))
                     /locus_tag="Smed_4523"
                     /note="molybdopterin cofactor binding site; other site"
                     /db_xref="CDD:239155"
     misc_feature    complement(1009468..1009821)
                     /locus_tag="Smed_4523"
                     /note="Nitrate reductases, NapA (Nitrate-R-NapA), NasA,
                     and NarB catalyze the reduction of nitrate to nitrite.
                     Monomeric Nas is located in the cytoplasm and participates
                     in nitrogen assimilation. Dimeric Nap is located in the
                     periplasm and is coupled to quinol...; Region:
                     MopB_CT_Nitrate-R-NapA-like; cd02791"
                     /db_xref="CDD:239192"
     misc_feature    complement(order(1009483..1009488,1009534..1009536,
                     1009573..1009575,1009768..1009779,1009783..1009797))
                     /locus_tag="Smed_4523"
                     /note="molybdopterin cofactor binding site; other site"
                     /db_xref="CDD:239192"
     misc_feature    complement(1008910..1009068)
                     /locus_tag="Smed_4523"
                     /note="BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD;
                     pfam04324"
                     /db_xref="CDD:218027"
     gene            complement(1011552..1011890)
                     /locus_tag="Smed_4524"
                     /db_xref="GeneID:5318499"
     CDS             complement(1011552..1011890)
                     /locus_tag="Smed_4524"
                     /note="TIGRFAM: nitrite reductase [NAD(P)H], small
                     subunit;
                     PFAM: Rieske [2Fe-2S] domain protein;
                     KEGG: sme:SMb20985 putative nitrite reductase [NAD(P)H],
                     small subunit protein"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase (NAD(P)H) small subunit"
                     /protein_id="YP_001313257.1"
                     /db_xref="GI:150376661"
                     /db_xref="InterPro:IPR005806"
                     /db_xref="InterPro:IPR012748"
                     /db_xref="GeneID:5318499"
                     /translation="MTTNWTAIGDINDIPLRGARCIRTPTGKIAVFRTAENEVFAIED
                     HCPHKGGPLSQGIVHGTAVTCPLHNWVISLETGKALGADEGEVRTIPVKNDNGALYVA
                     LESLALAAAE"
     misc_feature    complement(1011600..1011878)
                     /locus_tag="Smed_4524"
                     /note="Small subunit of nitrite reductase (NirD) family,
                     Rieske domain; composed of proteins similar to the
                     Bacillus subtilis small subunit of assimilatory nitrite
                     reductase containing a Rieske domain. The Rieske domain is
                     a [2Fe-2S] cluster binding domain...; Region:
                     Rieske_NirD_small_Bacillus; cd03530"
                     /db_xref="CDD:239606"
     misc_feature    complement(order(1011681..1011683,1011687..1011689,
                     1011696..1011698,1011744..1011749,1011753..1011755))
                     /locus_tag="Smed_4524"
                     /note="[2Fe-2S] cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239606"
     gene            complement(1011895..1014357)
                     /locus_tag="Smed_4525"
                     /db_xref="GeneID:5318500"
     CDS             complement(1011895..1014357)
                     /locus_tag="Smed_4525"
                     /note="TIGRFAM: nitrite reductase [NAD(P)H], large
                     subunit;
                     PFAM: FAD-dependent pyridine nucleotide-disulphide
                     oxidoreductase; nitrite/sulfite reductase hemoprotein
                     beta-component ferrodoxin domain protein; nitrite and
                     sulphite reductase 4Fe-4S region; BFD domain protein
                     [2Fe-2S]-binding domain protein;
                     KEGG: sme:SMb20984 putative nitrite reductase [NAD(P)H],
                     large subunit protein"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase (NAD(P)H) large subunit"
                     /protein_id="YP_001313258.1"
                     /db_xref="GI:150376662"
                     /db_xref="InterPro:IPR001100"
                     /db_xref="InterPro:IPR001327"
                     /db_xref="InterPro:IPR005117"
                     /db_xref="InterPro:IPR006066"
                     /db_xref="InterPro:IPR006067"
                     /db_xref="InterPro:IPR007419"
                     /db_xref="InterPro:IPR012744"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="GeneID:5318500"
                     /translation="MTETALEKLVVVGNGMAPGRMLEELFEKAPGRYAVTIFNAEPRV
                     NYDRIMLSPVLSGEKDYEEIIIHGDGWYIKHGITLYKGHKIVAIDREAKTVTSDHGVT
                     ESYDKLVIATGSVPFIIPVPGKDLRGVITYRDLDDVQAMLLAAQSREKAVVIGGGLLG
                     LEAAAGLQARGMDVTVLHVMPTLMERQLDPAAGYLLQKAVEERGIKVLTKANTKRILG
                     EEKVEGIELEDGRIIPATLVVMAVGIRPNAGLAKEAGLAVNRGIVVDAGMQTSDGNIM
                     ALGECAEVGGMVYGLVAPLYEMARVAASHLAGDRRAAFAHSDTPTKLKVTGINLYSVG
                     DFADGDGREEIVLRDATAGIYKRLVLKENRIVGAVLYGDTGDGAWFNDLLKRGTDICE
                     LRDTLIFGQAYQGGSPLDPMAAVAALPDDAEICGCNGVCKGKIVGAITSKGLTSLDDV
                     RAHTKASASCGSCTGLVEQIMSLTLGDSYNPAAVQPMCNCTDLGHDDVRRLIKAKKLK
                     TIPAVMQELEWKTSCGCAKCRPALNYYLVCDWPDEYADDYQSRFINERVHANIQKDGT
                     YSVVPRMWGGVTNSRELRAIADVADKFNVPLVKVTGGQRIDLLGIEKEDLPAVWADLN
                     KAGFVSGQAYAKGLRTVKTCVGSDWCRFGTQNSTGLGIRIEKFMWGSWTPAKLKMAVS
                     GCPRNCAEATCKDIGVICVDSGYEIHFAGAAGLDIKGTEVLGLVKTEDEALEHIVALT
                     QMYREQARYLERIYKWAKRVGLDEIRRQIMGDAERRKAYFDRFVFSQKFAQVDPWSER
                     VSGKDKHEFRPMATVGFNQAAE"
     misc_feature    complement(1011925..1014348)
                     /locus_tag="Smed_4525"
                     /note="NAD(P)H-nitrite reductase [Energy production and
                     conversion]; Region: NirB; COG1251"
                     /db_xref="CDD:224171"
     misc_feature    complement(1013668..1013910)
                     /locus_tag="Smed_4525"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:215691"
     misc_feature    complement(1012942..1013088)
                     /locus_tag="Smed_4525"
                     /note="BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD;
                     pfam04324"
                     /db_xref="CDD:218027"
     misc_feature    complement(1012738..1012905)
                     /locus_tag="Smed_4525"
                     /note="BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD;
                     pfam04324"
                     /db_xref="CDD:218027"
     misc_feature    complement(1012480..1012674)
                     /locus_tag="Smed_4525"
                     /note="Nitrite/Sulfite reductase ferredoxin-like half
                     domain; Region: NIR_SIR_ferr; pfam03460"
                     /db_xref="CDD:217572"
     gene            complement(1014420..1014737)
                     /locus_tag="Smed_4526"
                     /db_xref="GeneID:5318501"
     CDS             complement(1014420..1014737)
                     /locus_tag="Smed_4526"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313259.1"
                     /db_xref="GI:150376663"
                     /db_xref="GeneID:5318501"
                     /translation="MAQKFITKCKRPTFKPDGLLLAKGHSLRFARLFNAIGKRQSLGT
                     AFAFRKLLPSTAIEASPGAAFACQRHRRRKVFASVRVSPRSAISERRFFMPVPAGNET
                     EPT"
     gene            complement(1015026..1016333)
                     /locus_tag="Smed_4527"
                     /db_xref="GeneID:5318502"
     CDS             complement(1015026..1016333)
                     /locus_tag="Smed_4527"
                     /note="KEGG: sme:SMb21114 putative nitrate transport
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nitrate transport protein"
                     /protein_id="YP_001313260.1"
                     /db_xref="GI:150376664"
                     /db_xref="GeneID:5318502"
                     /translation="MNVLTKKSEFRGGKLSTGSALPAPGRIRHEGQRTIRAGFIPLVD
                     AAVLIAAAEFGFAQREGITLELVKDVSWANVRDRLAFRQFDIAHMLSPMPVAARLGLG
                     SNPSPTIAPFSLGRGGNAITLSTRIYGLMEEEGRLGGAADPLRNARALEAVVRSAAAA
                     GKPPLTLGVTYPFSSHNYELRYWLAAGGIDPDRDVKLVVVPPPMTSDALSAGAIDGFC
                     VGAPWNMIASERGVGRIVATKQDIWPSAPEKVIGMRPEWAEAKPDTVSRLIVALDRAA
                     RWSDVPENRARLAEVLAEDRHLGAPVDIIRRVLAGEFTIDPEGNRRVVENYFVFHAGF
                     ANFPRPSQALWIYSQMVRWGQTTLSREGFEASVSAYRPDLYRGALGKDALPADADSGS
                     LEGATDGDRFIDGHVFDPGRIEDYIKSFTVFGKDGVQTPVDDV"
     misc_feature    complement(1015254..1016306)
                     /locus_tag="Smed_4527"
                     /note="ABC-type nitrate/sulfonate/bicarbonate transport
                     systems, periplasmic components [Inorganic ion transport
                     and metabolism]; Region: TauA; COG0715"
                     /db_xref="CDD:223787"
     misc_feature    complement(1015455..1016237)
                     /locus_tag="Smed_4527"
                     /note="NMT1-like family; Region: NMT1_2; pfam13379"
                     /db_xref="CDD:222087"
     gene            complement(1016361..1016951)
                     /locus_tag="Smed_4528"
                     /db_xref="GeneID:5318503"
     CDS             complement(1016361..1016951)
                     /locus_tag="Smed_4528"
                     /note="PFAM: response regulator receiver; ANTAR domain
                     protein;
                     KEGG: rle:RL1994 putative two component assimilatory
                     nitrate reductase regulator response regulatory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver/ANTAR
                     domain-containing protein"
                     /protein_id="YP_001313261.1"
                     /db_xref="GI:150376665"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR005561"
                     /db_xref="GeneID:5318503"
                     /translation="MTHFDLTILVIDENAIRASIIEEGLREAGHGKVTVIHEVHGVAR
                     IIETLQPDVIVIDIENPNRDMMEHLFQLTRTVGRPIAMFVDRSDSAAIEAAVEAGVSA
                     YIVDGLRKERVKPILDMAVSRFKAFSRLQRELADAKSALEERKLVERAKGILMKMRGF
                     SEEEAFTLLRQTAMNEKKKIAEIAQSVVTAAGLLIR"
     misc_feature    complement(1016370..1016951)
                     /locus_tag="Smed_4528"
                     /note="Response regulator with putative antiterminator
                     output domain [Signal transduction mechanisms]; Region:
                     AmiR; COG3707"
                     /db_xref="CDD:226230"
     misc_feature    complement(1016637..1016927)
                     /locus_tag="Smed_4528"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(1016643..1016645,1016700..1016702,
                     1016757..1016759,1016781..1016783,1016913..1016918))
                     /locus_tag="Smed_4528"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(1016781..1016783)
                     /locus_tag="Smed_4528"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(1016757..1016765,1016769..1016774))
                     /locus_tag="Smed_4528"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(1016388..1016555)
                     /locus_tag="Smed_4528"
                     /note="ANTAR domain; Region: ANTAR; pfam03861"
                     /db_xref="CDD:202788"
     gene            complement(1017088..1017792)
                     /locus_tag="Smed_4529"
                     /db_xref="GeneID:5317968"
     CDS             complement(1017088..1017792)
                     /locus_tag="Smed_4529"
                     /note="PFAM: TfuA domain protein core;
                     KEGG: sme:SMb21116 putative protein, similar to gene
                     related to biosynthesis of peptide antibiotic
                     trifolitoxin"
                     /codon_start=1
                     /transl_table=11
                     /product="TfuA domain-containing protein"
                     /protein_id="YP_001313262.1"
                     /db_xref="GI:150376666"
                     /db_xref="InterPro:IPR012924"
                     /db_xref="GeneID:5317968"
                     /translation="MKVVFVGPTVPDAARLTGDKLTIRAPAGQGDILRAVRDGAAAIG
                     LIDGNFEYVAPVWHKEILFALSEGVAVFGSASMGALRAAECAAFGMVGIGEIYRQYAT
                     GELEDDSDVALLHAPEQLGYAPLTLPLVNIRSTLRRLLDAQSLSVEDCARIAEAAALI
                     FYKERTFAAIAARATIMANADLAIGRLRTGYVDQKRADGLELLKVLAGQPDVRQLAAR
                     DWEFRSTSLWERAFGY"
     misc_feature    complement(1017148..1017792)
                     /locus_tag="Smed_4529"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3482"
                     /db_xref="CDD:226013"
     gene            complement(1017885..1018343)
                     /locus_tag="Smed_4530"
                     /db_xref="GeneID:5317969"
     CDS             complement(1017885..1018343)
                     /locus_tag="Smed_4530"
                     /note="PFAM: helix-turn-helix domain protein;
                     KEGG: sme:SMb21117 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="YP_001313263.1"
                     /db_xref="GI:150376667"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="GeneID:5317969"
                     /translation="MNKKDPNPIDAFVGSRVRMRRLMIGLSQEKLADGLGITFQQVQK
                     YEKGTNRIGASRLQAIADILGVHPSFFFQQEEGSTQSGRPSGDIHESQEISSFVASKE
                     GIALNRAFLKIADPVLRKKIISLVAAMAQSPESDQTPAQSGTRHTEPLHG"
     misc_feature    complement(1017960..1018307)
                     /locus_tag="Smed_4530"
                     /note="Predicted transcriptional regulators
                     [Transcription]; Region: HipB; COG1396"
                     /db_xref="CDD:224314"
     misc_feature    complement(1018131..1018304)
                     /locus_tag="Smed_4530"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; Region: HTH_XRE; cd00093"
                     /db_xref="CDD:238045"
     misc_feature    complement(order(1018203..1018205,1018278..1018280,
                     1018290..1018292))
                     /locus_tag="Smed_4530"
                     /note="non-specific DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238045"
     misc_feature    complement(order(1018206..1018208,1018281..1018283))
                     /locus_tag="Smed_4530"
                     /note="salt bridge; other site"
                     /db_xref="CDD:238045"
     misc_feature    complement(order(1018200..1018205,1018215..1018217,
                     1018224..1018226,1018257..1018262))
                     /locus_tag="Smed_4530"
                     /note="sequence-specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238045"
     gene            1018574..1019110
                     /locus_tag="Smed_4531"
                     /db_xref="GeneID:5317970"
     CDS             1018574..1019110
                     /locus_tag="Smed_4531"
                     /EC_number="2.7.1.12"
                     /note="TIGRFAM: carbohydrate kinase, thermoresistant
                     glucokinase family;
                     PFAM: shikimate kinase;
                     KEGG: sme:SMb21119 putative gluconokinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="YP_001313264.1"
                     /db_xref="GI:150376668"
                     /db_xref="InterPro:IPR000623"
                     /db_xref="InterPro:IPR006001"
                     /db_xref="GeneID:5317970"
                     /translation="MSVEYKSEPNALRRFPGSIVVMGVSGSGKSSVGEAIAKACGYPF
                     LEGDALHPAENIRKMSEGVPLTDDDRWPWLDAIGERLASREPVVVSCSALRRIYRDKL
                     RESAPRGLAFVFLYGSEAVLSERMQHRTGHFMPSSLLQTQLATLEDPRGEAKTIAVDV
                     AHPLAEIVREALEGLARL"
     misc_feature    1018673..1019053
                     /locus_tag="Smed_4531"
                     /note="Gluconate kinase (GntK) catalyzes the phosphoryl
                     transfer from ATP to gluconate. The resulting product
                     gluconate-6-phoshate is an important precursor of
                     gluconate metabolism. GntK acts as a dimmer composed of
                     two identical subunits; Region: GntK; cd02021"
                     /db_xref="CDD:238979"
     misc_feature    1018676..1019101
                     /locus_tag="Smed_4531"
                     /note="Shikimate kinase; Region: SKI; pfam01202"
                     /db_xref="CDD:216360"
     gene            1019266..1020429
                     /locus_tag="Smed_4532"
                     /db_xref="GeneID:5317971"
     CDS             1019266..1020429
                     /locus_tag="Smed_4532"
                     /note="PFAM: acyl-CoA dehydrogenase domain protein;
                     Acyl-CoA dehydrogenase type 2 domain;
                     KEGG: sme:SMb21121 putative isovaleryl-CoA dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase domain-containing
                     protein"
                     /protein_id="YP_001313265.1"
                     /db_xref="GI:150376669"
                     /db_xref="InterPro:IPR006089"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR006092"
                     /db_xref="InterPro:IPR013107"
                     /db_xref="GeneID:5317971"
                     /translation="MFEAGLNFAFSEEIDALRESVRRFATERIAPLADEVDRKNAFPM
                     PLWREMGELGLLGITADEAHGGAGLGYLAHCVAMEEISRASASVGLSYGAHSNLCVNQ
                     INRNGSPAQKSTYLPKLISGEHVGALAMSEPGSGSDVVSMKLRADKRGDRYVLNGTKM
                     WITNGPDADVLVVYAKTDPAAGPRGITAFLVENTFPGFSTGRKLDKLGMRGSNTSELI
                     FTDCEVPQENVLGALGEGVKVLMSGLDYERVVLSAGPLGIMAACLDVVVPYLHERKQF
                     GQPIGEFQLMQGKLADMYVRMNAARAYVYAVAAACDRGETARKDAAGCILYAAEAATA
                     LALEAIQALGGNGYTNDFPAGRLLRDAKLYEIGAGTSEIRRMLIGRELFAETK"
     misc_feature    1019266..1020420
                     /locus_tag="Smed_4532"
                     /note="isovaleryl-CoA dehydrogenase; Region: PLN02519"
                     /db_xref="CDD:215284"
     misc_feature    1019290..1020417
                     /locus_tag="Smed_4532"
                     /note="Isovaleryl-CoA dehydrogenase; Region: IVD; cd01156"
                     /db_xref="CDD:173845"
     misc_feature    order(1019533..1019535,1019545..1019547,1019557..1019559,
                     1019674..1019676,1019752..1019754,1019815..1019817,
                     1019977..1019979,1019998..1020000,1020007..1020009,
                     1020016..1020018,1020352..1020357,1020364..1020372)
                     /locus_tag="Smed_4532"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173845"
     misc_feature    order(1019647..1019649,1019653..1019658,1019671..1019676,
                     1019746..1019748,1019752..1019754,1020373..1020375,
                     1020379..1020381)
                     /locus_tag="Smed_4532"
                     /note="FAD binding site [chemical binding]; other site"
                     /db_xref="CDD:173845"
     misc_feature    1020004..1020006
                     /locus_tag="Smed_4532"
                     /note="catalytic base [active]"
                     /db_xref="CDD:173845"
     gene            1020493..1022100
                     /locus_tag="Smed_4533"
                     /db_xref="GeneID:5317972"
     CDS             1020493..1022100
                     /locus_tag="Smed_4533"
                     /EC_number="6.4.1.3"
                     /note="PFAM: carboxyl transferase;
                     KEGG: sme:SMb21122 putative methylcrotonoyl-CoA
                     carboxylase non-biotinylated subunit protein"
                     /codon_start=1
                     /transl_table=11
                     /product="propionyl-CoA carboxylase"
                     /protein_id="YP_001313266.1"
                     /db_xref="GI:150376670"
                     /db_xref="InterPro:IPR000022"
                     /db_xref="InterPro:IPR011762"
                     /db_xref="InterPro:IPR011763"
                     /db_xref="GeneID:5317972"
                     /translation="MTVLRSHISPSSEGFKANRAAMAEAIAAIEDAVRLAASGGGDKA
                     RERHVSRGKLLPRDRVAALIDPGTPFLELGATAAHEMYNGDAPAAGLITGIGRISGRE
                     CMIVCNDPTVKGGTYYPMTVKKHLRAQEIAAENRLPCVYLVDSGGANLPNQDEVFPDR
                     DHFGRIFYNQANMSAAGIPQIAVVMGSCTAGGAYVPAMSDEAIIVEKQGTIFLAGPPL
                     VRAATGEVVSAEELGGADVHTRLSGVADHLARDDAHALALARRAVSALNYGKPWPVQR
                     IDPEPPLYDPEEIAGIVPADLKTPYDIREVIARLVDGSRFDEFKARFGTTLVCGFAHV
                     HGIPVGIVANNGVLFSESAVKGAHFVELCAQRRIPLVFLQNITGFMVGRKYETEGIAK
                     HGAKLVTAVATVKVPKITMLVGGSFGAGNYGMCGRAFSPRFLWTWPNSRISVMGGEQA
                     AGVLSSVRGEALKRSGLPWSEEEEARFRQPVLDLFERQSHPLYASARLWDDGVIDPRK
                     SRDVLALSLSAALNAPIEDTHFGLFRM"
     misc_feature    1020589..1022097
                     /locus_tag="Smed_4533"
                     /note="Acetyl-CoA carboxylase, carboxyltransferase
                     component (subunits alpha and beta) [Lipid metabolism];
                     Region: COG4799"
                     /db_xref="CDD:227136"
     misc_feature    1020616..>1021110
                     /locus_tag="Smed_4533"
                     /note="Acetyl-CoA carboxylase alpha subunit [Lipid
                     metabolism]; Region: AccA; cl17345"
                     /db_xref="CDD:247899"
     gene            1022112..1022498
                     /locus_tag="Smed_4534"
                     /db_xref="GeneID:5317973"
     CDS             1022112..1022498
                     /locus_tag="Smed_4534"
                     /note="PFAM: Endoribonuclease L-PSP;
                     KEGG: sme:SMb21123 hypothetical membrane-anchored protein,
                     similar to putative translation initiation inhibitor"
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease L-PSP"
                     /protein_id="YP_001313267.1"
                     /db_xref="GI:150376671"
                     /db_xref="InterPro:IPR006175"
                     /db_xref="GeneID:5317973"
                     /translation="MLKRDNINALNAPQPRGGYSQAVSIEDFRRVLFISGQIPVNSDE
                     VVPEGFEAQARQVWRNVDAQLKAAGMSKTDIVKVTTYLADRQHAIANREIRNDYLGSL
                     APAMTVVVAGIFDSAWLIEVEVTAAQ"
     misc_feature    1022166..1022489
                     /locus_tag="Smed_4534"
                     /note="YjgF, YER057c, and UK114 belong to a large family
                     of proteins present in bacteria, archaea, and eukaryotes
                     with no definitive function. The conserved domain is
                     similar in structure to chorismate mutase but there is no
                     sequence similarity and no...; Region:
                     YjgF_YER057c_UK114_family; cd00448"
                     /db_xref="CDD:100004"
     misc_feature    order(1022166..1022171,1022178..1022180,1022184..1022186,
                     1022193..1022195,1022208..1022210,1022214..1022219,
                     1022331..1022333,1022337..1022342,1022346..1022348,
                     1022352..1022354,1022385..1022387,1022394..1022396,
                     1022421..1022444,1022472..1022474,1022478..1022480,
                     1022484..1022486)
                     /locus_tag="Smed_4534"
                     /note="homotrimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:100004"
     misc_feature    order(1022166..1022168,1022373..1022375,1022385..1022387,
                     1022427..1022429,1022472..1022474)
                     /locus_tag="Smed_4534"
                     /note="putative active site [active]"
                     /db_xref="CDD:100004"
     gene            1022515..1024503
                     /locus_tag="Smed_4535"
                     /db_xref="GeneID:5317974"
     CDS             1022515..1024503
                     /locus_tag="Smed_4535"
                     /note="PFAM: biotin/lipoyl attachment domain-containing
                     protein; Carbamoyl-phosphate synthase L chain ATP-binding;
                     Carbamoyl-phosphate synthetase large chain domain protein;
                     biotin carboxylase domain protein;
                     KEGG: sme:SMb21124 putative methylcrotonoyl-CoA
                     carboxylase biotinylated subunit protein"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase L chain
                     ATP-binding"
                     /protein_id="YP_001313268.1"
                     /db_xref="GI:150376672"
                     /db_xref="InterPro:IPR000089"
                     /db_xref="InterPro:IPR001882"
                     /db_xref="InterPro:IPR005479"
                     /db_xref="InterPro:IPR005481"
                     /db_xref="InterPro:IPR005482"
                     /db_xref="InterPro:IPR011761"
                     /db_xref="InterPro:IPR011764"
                     /db_xref="GeneID:5317974"
                     /translation="MFSKLLIANRGEIACRIIRTARRLGIRTAAVYSDADGDALHVAL
                     ADEAIRIGAAPAAQSYLAIGSIVQAARSVGAEAIHPGYGFLSENADFAEAVGEAGMVF
                     VGPPPAAIRAMGLKDAAKALMERAGVPVVPGYHGEEQDASFLAERAREIGYPVLIKAR
                     AGGGGKGMRRVERQDDFGSALEAARREAASAFGDGSVLLERYLTKPRHIEMQIFGDRQ
                     GNIVHLFERDCSLQRRHQKVIEEAPAPGMTAEVRRAMGDAAVRAAQAIGYVGAGTVEF
                     IADVTNGLEPDHFYFMEMNTRLQVEHPVTEAITGTDLVEWQLRVAAGEPLPKKQADIS
                     INGWAFEARFYAEDPVRGFLPATGRLTHLSFPEDTARVDAGVRQGDTITPYYDPLIAK
                     LIVHGQNRSAALGKLQDALKECRIGGTVTNLDFLIRLTEEHEFRSGHPDTGLIDRETE
                     RLTAPVVPGDEALALAAIISTGALEPEMSTDPWSSLGSWQIWGDAHRTVAIDHADVRA
                     TVTLASRGRDQFAVRAGGSTLPVLVLDRIEGGARLEVAGKQRLIRFARDRESMTLFHH
                     GRNLVFHLPDGLAGGQSSEVAEDELLAPMPGLVKLVRVGAGDTVSKGQPLIVLEAMKM
                     ELTLSASREGTIANVHVTEGAQVSEGMVLVTLMEEAAQ"
     misc_feature    1022515..1024488
                     /locus_tag="Smed_4535"
                     /note="Acetyl/propionyl-CoA carboxylase, alpha subunit
                     [Lipid metabolism]; Region: COG4770"
                     /db_xref="CDD:227111"
     misc_feature    1022518..1022841
                     /locus_tag="Smed_4535"
                     /note="Carbamoyl-phosphate synthase L chain, N-terminal
                     domain; Region: CPSase_L_chain; pfam00289"
                     /db_xref="CDD:201133"
     misc_feature    1022860..1023495
                     /locus_tag="Smed_4535"
                     /note="ATP-grasp domain; Region: ATP-grasp_4; cl17255"
                     /db_xref="CDD:247809"
     misc_feature    1023535..1023852
                     /locus_tag="Smed_4535"
                     /note="Biotin carboxylase C-terminal domain; Region:
                     Biotin_carb_C; smart00878"
                     /db_xref="CDD:214878"
     misc_feature    1024282..1024482
                     /locus_tag="Smed_4535"
                     /note="The biotinyl-domain or biotin carboxyl carrier
                     protein (BCCP) domain is present in all biotin-dependent
                     enzymes, such as acetyl-CoA carboxylase, pyruvate
                     carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA
                     carboxylase, geranyl-CoA carboxylase; Region:
                     biotinyl_domain; cd06850"
                     /db_xref="CDD:133459"
     misc_feature    order(1024351..1024353,1024378..1024386,1024405..1024407)
                     /locus_tag="Smed_4535"
                     /note="carboxyltransferase (CT) interaction site; other
                     site"
                     /db_xref="CDD:133459"
     misc_feature    1024381..1024383
                     /locus_tag="Smed_4535"
                     /note="biotinylation site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:133459"
     gene            1024500..1025369
                     /locus_tag="Smed_4536"
                     /db_xref="GeneID:5317975"
     CDS             1024500..1025369
                     /locus_tag="Smed_4536"
                     /EC_number="4.1.3.4"
                     /note="catalyzes the formation of acetoacetate and
                     acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="YP_001313269.1"
                     /db_xref="GI:150376673"
                     /db_xref="InterPro:IPR000891"
                     /db_xref="GeneID:5317975"
                     /translation="MTPPARESATIVEMAPRDGLQNEPRLVATEDKIRLVDLLSDCGY
                     GRIEVTSFVSPRWVPQMADAPAVMTGILRRAGTRYAALTPNMRGFEAALAARADEVAV
                     FASASESFSEKNINCSIAESIERFRPVAEASRRHGVPLRGYVSCVVECPYEGAIAPAA
                     VARVTRLLAELGCYEISLGDTIGSGTPESVDRMLTTVRREVDAKALAGHFHDTSGRAL
                     ENIGVALEHGLRVFDASAGGLGGCPYAPGAAGNVDSLEVRAFLETRGFNTGLDLEKLD
                     RAGAFARSLRSAA"
     misc_feature    1024530..1025351
                     /locus_tag="Smed_4536"
                     /note="3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM
                     barrel domain; Region: DRE_TIM_HMGL; cd07938"
                     /db_xref="CDD:163676"
     misc_feature    order(1024548..1024553,1024560..1024562,1024650..1024652,
                     1024656..1024658,1024806..1024808,1025124..1025126,
                     1025130..1025132,1025250..1025252)
                     /locus_tag="Smed_4536"
                     /note="active site"
                     /db_xref="CDD:163676"
     misc_feature    order(1024548..1024553,1024641..1024643)
                     /locus_tag="Smed_4536"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:163676"
     misc_feature    order(1024551..1024553,1025124..1025126,1025130..1025132,
                     1025250..1025252)
                     /locus_tag="Smed_4536"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163676"
     gene            1025366..1026151
                     /locus_tag="Smed_4537"
                     /db_xref="GeneID:5317976"
     CDS             1025366..1026151
                     /locus_tag="Smed_4537"
                     /EC_number="4.2.1.17"
                     /note="Catalyzes the reversible hydration of unsaturated
                     fatty acyl-CoA to beta-hydroxyacyl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="YP_001313270.1"
                     /db_xref="GI:150376674"
                     /db_xref="InterPro:IPR001753"
                     /db_xref="GeneID:5317976"
                     /translation="MTFATIRFAVDQRGVARVTLARPNKHNALSAAMIAEMTDVAGRL
                     ATDASVRAVILDAEGKSFCAGADLEWMREQFSADRATRISEATRLAMMLKALNGLPKP
                     LIARVHGNAFGGGVGLISVCDTVICASGAQFGLTETRLGLIPATISPYVIARTGEAKA
                     RPLFMSARVFGAEEAKVAGFVTTIVDDSMLDGAVEAAVTAYLVAAPGAAGRAKRLARS
                     LGLPITDAVISDTIEQLADVWETDEAREGVSSFFERRNPSWRR"
     misc_feature    1025366..1026148
                     /locus_tag="Smed_4537"
                     /note="enoyl-CoA hydratase; Provisional; Region: PRK07468"
                     /db_xref="CDD:180987"
     misc_feature    1025405..1025953
                     /locus_tag="Smed_4537"
                     /note="Crotonase/Enoyl-Coenzyme A (CoA) hydratase
                     superfamily. This superfamily contains a diverse set of
                     enzymes including enoyl-CoA hydratase, napthoate synthase,
                     methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA
                     dehydratase, and dienoyl-CoA isomerase; Region:
                     crotonase-like; cd06558"
                     /db_xref="CDD:119339"
     misc_feature    order(1025441..1025443,1025447..1025449,1025543..1025545,
                     1025555..1025569,1025693..1025695,1025699..1025707,
                     1025771..1025776,1025783..1025785)
                     /locus_tag="Smed_4537"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:119339"
     misc_feature    order(1025561..1025563,1025705..1025707)
                     /locus_tag="Smed_4537"
                     /note="oxyanion hole (OAH) forming residues; other site"
                     /db_xref="CDD:119339"
     misc_feature    order(1025645..1025647,1025669..1025671,1025732..1025743,
                     1025777..1025788,1025801..1025803,1025807..1025815,
                     1025819..1025824,1025837..1025842,1025846..1025851,
                     1025855..1025860,1025867..1025869,1025900..1025902,
                     1025909..1025911)
                     /locus_tag="Smed_4537"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119339"
     gene            1026227..1026598
                     /locus_tag="Smed_4538"
                     /db_xref="GeneID:5317977"
     CDS             1026227..1026598
                     /locus_tag="Smed_4538"
                     /note="KEGG: sme:SMb21127 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313271.1"
                     /db_xref="GI:150376675"
                     /db_xref="GeneID:5317977"
                     /translation="MMAVEFQIAAARFGDDHSPFLSARLVADRLGVTLAELAKLIGVA
                     RNTLTAKSGARKVDSALSRVVRILAMASEMAGDESRAVIWFKHQPIPGWAGKTAFDLV
                     GEGKADKVLAYLESVRAGVYA"
     misc_feature    1026428..1026589
                     /locus_tag="Smed_4538"
                     /note="Protein of unknown function (DUF2384); Region:
                     DUF2384; pfam09722"
                     /db_xref="CDD:204292"
     gene            1026604..1027104
                     /locus_tag="Smed_4539"
                     /db_xref="GeneID:5317978"
     CDS             1026604..1027104
                     /locus_tag="Smed_4539"
                     /note="PFAM: RES domain protein;
                     KEGG: sme:SMb21128 conserved hypothetical
                     membrane-anchored protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RES domain-containing protein"
                     /protein_id="YP_001313272.1"
                     /db_xref="GI:150376676"
                     /db_xref="InterPro:IPR014914"
                     /db_xref="GeneID:5317978"
                     /translation="MEALTLWRAFVPRWAHMPLSGAGAARFGGRWNPVGVPALYAARE
                     LSTAWAEYNQGFVQHPALIVQLELRDAVLADLTDFKVLADLDVDETIHSCEWRDMLDK
                     GAVPQTHQLRTALLARDYHGVIYPSFMSPGGTCVALWRWNGAKEPRLDVIDPEGRLPK
                     SPASWV"
     misc_feature    1026607..1027095
                     /locus_tag="Smed_4539"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG5654"
                     /db_xref="CDD:227941"
     gene            complement(1027229..1028599)
                     /locus_tag="Smed_4540"
                     /db_xref="GeneID:5319041"
     CDS             complement(1027229..1028599)
                     /locus_tag="Smed_4540"
                     /note="PFAM: FAD linked oxidase domain protein;
                     KEGG: sme:SMb21129 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD linked oxidase domain-containing protein"
                     /protein_id="YP_001313273.1"
                     /db_xref="GI:150376677"
                     /db_xref="InterPro:IPR004113"
                     /db_xref="InterPro:IPR006094"
                     /db_xref="GeneID:5319041"
                     /translation="MSVIEELMAALGNAVLTGDRITERYRSDASLSGRTLPLAVVRPG
                     SVDEVAVALKICNAHGQCVVPQGGLTGLAGGANPRAGDIAVSLERLSGIEEVDATASS
                     MTVLAGTPLEVAQRAAEDAGFLLPIDLGARGSCQIGGNLATNAGGIRVIRNGVARDNV
                     LGLEAVLADGTVVSSMNKMIKNNTGYDLRQLFIGSEGTLGIITRAVLRLRPLPTGRLT
                     ALCALDSYSEVVTLLKRAQQELPGLGAYEAMWESYFRFNSEADGLRLFESCPAFAVIV
                     EQDLQGHDAESERFEAFLGRALEDGVIGDALVAQSQKEAQAFWRIREGHALDRLPLLL
                     NFDVSLAIGDIGRFADECGQALRAKFPEAHVSFFGHVGDSNLHIAFSDPGATEETIHA
                     VDDIVYALVGTYRGSVSAEHGIGLLKRDFLHYSRSPAELELMRRIKSALDPNGILNPG
                     KVLGSV"
     misc_feature    complement(1027232..1028584)
                     /locus_tag="Smed_4540"
                     /note="FAD/FMN-containing dehydrogenases [Energy
                     production and conversion]; Region: GlcD; COG0277"
                     /db_xref="CDD:223354"
     misc_feature    complement(1028081..1028491)
                     /locus_tag="Smed_4540"
                     /note="FAD binding domain; Region: FAD_binding_4;
                     pfam01565"
                     /db_xref="CDD:216574"
     gene            complement(1028728..1029831)
                     /locus_tag="Smed_4541"
                     /db_xref="GeneID:5319042"
     CDS             complement(1028728..1029831)
                     /locus_tag="Smed_4541"
                     /note="TIGRFAM: sulfate ABC transporter, ATPase subunit;
                     PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21130 putative sulfate uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter ATPase"
                     /protein_id="YP_001313274.1"
                     /db_xref="GI:150376678"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005666"
                     /db_xref="GeneID:5319042"
                     /translation="MEVRVQNIRKEFARFPALDNVSLDIRSGELIALLGPSGSGKTTL
                     LRLVAGLESPTGGTIFFGDDDASKKTVQERNIGFVFQHYALFRHMTVLDNVAFGLKVR
                     TAKRRPPAAEIRRRALDLLDLVQLSGLEKRYPAQLSGGQRQRVALARAMAVEPNVLLL
                     DEPFGALDAQVRKELRRWLREIHDRTGHTTIFVTHDQEEALELADRVVVMSKGTIEQV
                     GSPDEIYDHPVSPFVYGFIGQSNCLDVTLANGEIWLEDRPIGLRAANEPDGPATLYFR
                     PHDVELIDGCGGCLAGLVTASRRVAGTRHLELELGRTHPRVEIELPPERAAFADHTRI
                     AFRPTRWKLFQKGERRITAREEVVVPELEATGT"
     misc_feature    complement(1028800..1029831)
                     /locus_tag="Smed_4541"
                     /note="ABC-type sulfate/molybdate transport systems,
                     ATPase component [Inorganic ion transport and metabolism];
                     Region: CysA; COG1118"
                     /db_xref="CDD:224043"
     misc_feature    complement(1029115..1029831)
                     /locus_tag="Smed_4541"
                     /note="ATP-binding cassette domain of the sulfate
                     transporter; Region: ABC_CysA_sulfate_importer; cd03296"
                     /db_xref="CDD:213263"
     misc_feature    complement(1029706..1029729)
                     /locus_tag="Smed_4541"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213263"
     misc_feature    complement(order(1029247..1029249,1029346..1029351,
                     1029589..1029591,1029703..1029711,1029715..1029720))
                     /locus_tag="Smed_4541"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213263"
     misc_feature    complement(1029589..1029600)
                     /locus_tag="Smed_4541"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213263"
     misc_feature    complement(1029394..1029423)
                     /locus_tag="Smed_4541"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213263"
     misc_feature    complement(1029346..1029363)
                     /locus_tag="Smed_4541"
                     /note="Walker B; other site"
                     /db_xref="CDD:213263"
     misc_feature    complement(1029328..1029339)
                     /locus_tag="Smed_4541"
                     /note="D-loop; other site"
                     /db_xref="CDD:213263"
     misc_feature    complement(1029241..1029261)
                     /locus_tag="Smed_4541"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213263"
     misc_feature    complement(1028815..1028982)
                     /locus_tag="Smed_4541"
                     /note="TOBE-like domain; Region: TOBE_3; pfam12857"
                     /db_xref="CDD:221811"
     gene            complement(1029847..1030713)
                     /locus_tag="Smed_4542"
                     /db_xref="GeneID:5319043"
     CDS             complement(1029847..1030713)
                     /locus_tag="Smed_4542"
                     /note="TIGRFAM: sulfate ABC transporter, inner membrane
                     subunit; sulfate ABC transporter, inner membrane subunit
                     CysW;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb21131 putative sulfate uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter permease"
                     /protein_id="YP_001313275.1"
                     /db_xref="GI:150376679"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR005667"
                     /db_xref="InterPro:IPR011866"
                     /db_xref="GeneID:5319043"
                     /translation="MAHDASSTLVTTATSETRLSRGILTAVALGFVLLFLLLPLATVF
                     IEAFRKGPAEFFAALRDPETFSAIRLTLLVAGIAVPLNLVFGVAAAWAIAKFEFKGKA
                     FLTTLIDLPFSVSPVISGLVFVLLFSSQSMLGPILQSYDIQILFAVPGLVLATVFVTF
                     PFVARELIPLMQEQGTADEEAALSLGATGWQTFWHVTLPNIKWGLLYGVLLCNARAMG
                     EFGAVSVVSGHIRGQTNTMPLQVEILYNEYNFVAAFAVAALLALLALVTLVLKTALEL
                     RYSDEIAASRRH"
     misc_feature    complement(1029967..1030512)
                     /locus_tag="Smed_4542"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1029967..1029969,1029997..1030002,
                     1030039..1030044,1030051..1030062,1030081..1030083,
                     1030090..1030095,1030135..1030137,1030186..1030188,
                     1030195..1030200,1030210..1030212,1030216..1030221,
                     1030228..1030230,1030234..1030236,1030243..1030248,
                     1030342..1030344,1030348..1030353,1030360..1030389,
                     1030393..1030404,1030432..1030434,1030447..1030452,
                     1030459..1030464))
                     /locus_tag="Smed_4542"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1030045..1030062,1030342..1030386))
                     /locus_tag="Smed_4542"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1029967..1029969,1029997..1029999,
                     1030006..1030008,1030042..1030044,1030261..1030263,
                     1030342..1030344))
                     /locus_tag="Smed_4542"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1030114..1030116,1030126..1030131,
                     1030147..1030185))
                     /locus_tag="Smed_4542"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1030703..1031560)
                     /locus_tag="Smed_4543"
                     /db_xref="GeneID:5319044"
     CDS             complement(1030703..1031560)
                     /locus_tag="Smed_4543"
                     /note="TIGRFAM: sulfate ABC transporter, inner membrane
                     subunit; sulfate ABC transporter, inner membrane subunit
                     CysT;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb21132 putative sulfate uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter permease"
                     /protein_id="YP_001313276.1"
                     /db_xref="GI:150376680"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR005667"
                     /db_xref="InterPro:IPR011865"
                     /db_xref="GeneID:5319044"
                     /translation="MAARTSTRWRFRQPSVIPGFGLALGVTLAWLTIIVLVPLSGLLW
                     RSSSLGWSKFAELALDERTVNALTISFGTAFIAAVVNLVFGVLLAWVLVRYRFPGKRV
                     IDAMVDLPFALPTAVAGIALTTLYAPNGWIGSLLAPLGIKVAFTPAGIVVALIFVGLP
                     FVVRTVQPIMEEIDKEVEEAAATLGATRFQTISRVLLPGLLPAGLTGFALAFARGVGE
                     YGSVIFIAGNLPYVSEIAPLLIVIRLEEFNYPAATAIAGVMLLLSFLMLLVINVIQAW
                     SRRRYGYGA"
     misc_feature    complement(1030715..1031527)
                     /locus_tag="Smed_4543"
                     /note="ABC-type sulfate transport system, permease
                     component [Posttranslational modification, protein
                     turnover, chaperones]; Region: CysU; COG0555"
                     /db_xref="CDD:223629"
     misc_feature    complement(1030787..1031362)
                     /locus_tag="Smed_4543"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1030793..1030798,1030802..1030807,
                     1030814..1030819,1030847..1030852,1030889..1030894,
                     1030901..1030912,1030931..1030933,1030940..1030945,
                     1030985..1030987,1031036..1031038,1031045..1031050,
                     1031060..1031062,1031066..1031071,1031078..1031080,
                     1031084..1031086,1031093..1031098,1031192..1031194,
                     1031198..1031203,1031210..1031239,1031243..1031254,
                     1031282..1031284,1031297..1031302,1031309..1031314))
                     /locus_tag="Smed_4543"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1030895..1030912,1031192..1031236))
                     /locus_tag="Smed_4543"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1030817..1030819,1030847..1030849,
                     1030856..1030858,1030892..1030894,1031111..1031113,
                     1031192..1031194))
                     /locus_tag="Smed_4543"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1030964..1030966,1030976..1030981,
                     1030997..1031035))
                     /locus_tag="Smed_4543"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1031566..1032591)
                     /locus_tag="Smed_4544"
                     /db_xref="GeneID:5319045"
     CDS             complement(1031566..1032591)
                     /locus_tag="Smed_4544"
                     /note="TIGRFAM: sulfate ABC transporter, periplasmic
                     sulfate-binding protein;
                     PFAM: extracellular solute-binding protein family 1;
                     KEGG: sme:SMb21133 putative sulfate uptake ABC transporter
                     periplasmic solute-binding protein precursor, similar to
                     Y11244"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter periplasmic
                     sulfate-binding protein"
                     /protein_id="YP_001313277.1"
                     /db_xref="GI:150376681"
                     /db_xref="InterPro:IPR000957"
                     /db_xref="InterPro:IPR005669"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5319045"
                     /translation="MSSNRLAGIAKLALVVGSLQLGSVGLVHADTTILNVSYDPTREL
                     YKEFNAAFAEKWQADTGETVTIQTSHGGSGKQARSVIDGLEADVVTLALEADIDAIAR
                     ESGKIPADWKTRLENNSSPYTSTIVFLVRKGNPKGIKDWGDLVREDVQVITPNPKTSG
                     GARWNFLAAWAWARAANNGDDTKAQEYVTQLFKHVPVLDTGARGATTTFVQRGLGDVL
                     LAWENEAYLSLEELGPDNFDIVTPSISIKAEPPVALVDGNVDRKGTRKVAEAYLDYLY
                     SDAGQKIAAKHYYRPFKPEAADAEDTARFKELKLVTINDFGGWKEAQPKFFGDGGIFD
                     QIYRPGQ"
     sig_peptide     complement(1032502..1032591)
                     /locus_tag="Smed_4544"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.991) with cleavage site probability 0.989 at
                     residue 30"
     misc_feature    complement(1031569..1032558)
                     /locus_tag="Smed_4544"
                     /note="ABC-type sulfate transport system, periplasmic
                     component [Inorganic ion transport and metabolism];
                     Region: Sbp; COG1613"
                     /db_xref="CDD:224529"
     misc_feature    complement(1031722..1032435)
                     /locus_tag="Smed_4544"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_11; pfam13531"
                     /db_xref="CDD:222203"
     gene            complement(1032855..1033913)
                     /locus_tag="Smed_4545"
                     /db_xref="GeneID:5319046"
     CDS             complement(1032855..1033913)
                     /locus_tag="Smed_4545"
                     /note="PFAM: alanine racemase domain protein;
                     KEGG: sme:SMb21134 putative amino acid processing enzyme,
                     similar to low specificity D-threonine aldolase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase domain-containing protein"
                     /protein_id="YP_001313278.1"
                     /db_xref="GI:150376682"
                     /db_xref="InterPro:IPR001608"
                     /db_xref="GeneID:5319046"
                     /translation="MTLPIETPAVLVDLDIARRNILAFQAYADRHGIRVRPHIKTHKL
                     PQLAELQLDSGAIGITCQKVTEAEAMVDGSARIKEVLITYNLLGEEKLARLARLSEKV
                     TVSVVADNATVVDGLGAFFADAGKPMTVLVECNTGAERCGVATPAEAARLAMRIAAAP
                     GLRFGGLMTYPPADGAARVQTFMSEAKQLIEARGIEVPCVTSGGTPGMMQAAEAPVAS
                     EHRPGTYIYNDRSLVARGVASWDDCALTVLATVVSVPSENRAIIDAGSKVLTSDLLGL
                     TGYGHVLDRDDIRIDQLSEEHGRLVSDGSIRLTVGQQLRIVPNHACVVTNMVDAVHVI
                     EDGTPKGTWPVVARGRVL"
     misc_feature    complement(1032873..1033913)
                     /locus_tag="Smed_4545"
                     /note="Predicted amino acid aldolase or racemase [Amino
                     acid transport and metabolism]; Region: COG3616"
                     /db_xref="CDD:226143"
     misc_feature    complement(1032867..1033901)
                     /locus_tag="Smed_4545"
                     /note="Type III Pyridoxal 5-phosphate (PLP)-Dependent
                     Enzymes, Low Specificity D-Threonine Aldolase-like;
                     Region: PLPDE_III_LS_D-TA_like; cd06820"
                     /db_xref="CDD:143494"
     misc_feature    complement(order(1032918..1032920,1033113..1033118,
                     1033125..1033127,1033131..1033133,1033137..1033139,
                     1033149..1033160,1033488..1033499,1033566..1033568,
                     1033578..1033580,1033587..1033589,1033641..1033643,
                     1033698..1033700,1033716..1033721,1033725..1033730,
                     1033788..1033790,1033794..1033796,1033893..1033895))
                     /locus_tag="Smed_4545"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143494"
     misc_feature    complement(order(1033116..1033118,1033242..1033253,
                     1033299..1033304,1033404..1033406,1033494..1033496,
                     1033515..1033517,1033665..1033667,1033734..1033736,
                     1033794..1033796,1033800..1033802))
                     /locus_tag="Smed_4545"
                     /note="active site"
                     /db_xref="CDD:143494"
     misc_feature    complement(order(1033242..1033253,1033299..1033304,
                     1033404..1033406,1033515..1033517,1033665..1033667,
                     1033734..1033736,1033794..1033796,1033800..1033802))
                     /locus_tag="Smed_4545"
                     /note="pyridoxal 5'-phosphate (PLP) binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:143494"
     misc_feature    complement(order(1033242..1033244,1033404..1033406,
                     1033494..1033496,1033794..1033796))
                     /locus_tag="Smed_4545"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:143494"
     misc_feature    complement(1033794..1033796)
                     /locus_tag="Smed_4545"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:143494"
     gene            1034072..1034914
                     /locus_tag="Smed_4546"
                     /db_xref="GeneID:5319047"
     CDS             1034072..1034914
                     /locus_tag="Smed_4546"
                     /note="PFAM: extracellular solute-binding protein family
                     3;
                     KEGG: sme:SMb21135 putative amino acid uptake ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313279.1"
                     /db_xref="GI:150376683"
                     /db_xref="InterPro:IPR001638"
                     /db_xref="GeneID:5319047"
                     /translation="MISKFTAVAGFVAAVLAGMPAHAQQASSKLDEVLSRGHLILGTG
                     STNAPWHFKSAEDKLQGFDVDMGRIIAKALFGDPEKIEFVNQSSDARIPNITTGKVDI
                     TCQFMTVTGERAQQVAFTIPYYREGVGLMLKADGKYGDYEALKAAGSSVTISVLQNVY
                     AEDMVHAALPEAAVDQYESVDLIYQALESGRADAAATDQSSLAWYMTQNSGRYKDAGY
                     GWNPQTYACGVRRGDQDWLNFVNTALHEAMTGVEFDFYAKSFKTWFGKDLTPPEIGFP
                     VEYK"
     sig_peptide     1034072..1034143
                     /locus_tag="Smed_4546"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.995 at
                     residue 24"
     misc_feature    1034186..1034869
                     /locus_tag="Smed_4546"
                     /note="Bacterial extracellular solute-binding proteins,
                     family 3; Region: SBP_bac_3; pfam00497"
                     /db_xref="CDD:215950"
     misc_feature    1034186..1034863
                     /locus_tag="Smed_4546"
                     /note="Bacterial periplasmic transport systems use
                     membrane-bound complexes and substrate-bound,
                     membrane-associated, periplasmic binding proteins (PBPs)
                     to transport a wide variety of  substrates, such as, amino
                     acids, peptides, sugars, vitamins and inorganic...;
                     Region: PBPb; cd00134"
                     /db_xref="CDD:238078"
     misc_feature    order(1034210..1034212,1034333..1034335,1034408..1034410,
                     1034549..1034551,1034663..1034665)
                     /locus_tag="Smed_4546"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238078"
     misc_feature    order(1034612..1034614,1034624..1034626,1034642..1034644)
                     /locus_tag="Smed_4546"
                     /note="membrane-bound complex binding site; other site"
                     /db_xref="CDD:238078"
     misc_feature    1034738..1034755
                     /locus_tag="Smed_4546"
                     /note="hinge residues; other site"
                     /db_xref="CDD:238078"
     gene            1034975..1035637
                     /locus_tag="Smed_4547"
                     /db_xref="GeneID:5319048"
     CDS             1034975..1035637
                     /locus_tag="Smed_4547"
                     /note="TIGRFAM: polar amino acid ABC transporter, inner
                     membrane subunit;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb21136 putative amino acid uptake ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polar amino acid ABC transporter inner membrane
                     subunit"
                     /protein_id="YP_001313280.1"
                     /db_xref="GI:150376684"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR010065"
                     /db_xref="GeneID:5319048"
                     /translation="MTYSLNFAAVWRSFDLLLQGLSLSLGLAVVAIVVGCMIGLITAF
                     GLVSKSVALRKPAGFYVTAIRNTPILVLVLFSYFALPELGVRLGKIESFVLTLAIYSG
                     AYLAEVFRGGLIAIPPGQREAGLAIGLTEMQIRTSITIPLMLRSVLPSLGSTIISLFK
                     DTSLAAAIAVPELTFEARKINVESFRVIETWIVASCLYVATCSLLAALMRGVERRLAV
                     PR"
     misc_feature    1035056..1035490
                     /locus_tag="Smed_4547"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1035083..1035088,1035095..1035100,1035113..1035115,
                     1035143..1035154,1035158..1035187,1035194..1035199,
                     1035203..1035205,1035269..1035274,1035278..1035280,
                     1035284..1035286,1035293..1035298,1035302..1035304,
                     1035314..1035319,1035326..1035328,1035377..1035379,
                     1035419..1035424,1035431..1035433,1035452..1035463,
                     1035470..1035475)
                     /locus_tag="Smed_4547"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1035161..1035205,1035452..1035469)
                     /locus_tag="Smed_4547"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1035203..1035205,1035254..1035256,1035470..1035472)
                     /locus_tag="Smed_4547"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1035329..1035367,1035383..1035388,1035398..1035400)
                     /locus_tag="Smed_4547"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1035643..1036302
                     /locus_tag="Smed_4548"
                     /db_xref="GeneID:5319049"
     CDS             1035643..1036302
                     /locus_tag="Smed_4548"
                     /note="TIGRFAM: polar amino acid ABC transporter, inner
                     membrane subunit;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb21137 putative amino acid uptake ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polar amino acid ABC transporter inner membrane
                     subunit"
                     /protein_id="YP_001313281.1"
                     /db_xref="GI:150376685"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR010065"
                     /db_xref="GeneID:5319049"
                     /translation="MEVSFIDQLWLARIPLFKGLGISVSISFLSIVAGTVLGVFVGLA
                     LVYGYRPVRWIVRGYTDFIRGTPVLVLVLASYYVLSAIGIDLGPFQAGVLALAVFCSS
                     HVGELVRGALQSIPKGQTEAAKAIGLTFAQTFAYVLGPQALRQALPAWVNTAAEMVKA
                     STLLSIIGVGELLLRTQEVISRTFMSLEFYFFAGFLYFVINYGIERFGRYVERKTAVP
                     S"
     misc_feature    1035685..1036287
                     /locus_tag="Smed_4548"
                     /note="ABC-type arginine transport system, permease
                     component [Amino acid transport and metabolism]; Region:
                     ArtQ; COG4215"
                     /db_xref="CDD:226670"
     misc_feature    1035700..1036254
                     /locus_tag="Smed_4548"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1035748..1035753,1035760..1035765,1035778..1035780,
                     1035808..1035819,1035823..1035852,1035859..1035864,
                     1035868..1035870,1035934..1035939,1035943..1035945,
                     1035949..1035951,1035958..1035963,1035967..1035969,
                     1035979..1035984,1035991..1035993,1036042..1036044,
                     1036084..1036089,1036096..1036098,1036117..1036128,
                     1036135..1036140,1036177..1036182,1036210..1036215,
                     1036222..1036227,1036231..1036236,1036243..1036248)
                     /locus_tag="Smed_4548"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1035826..1035870,1036117..1036134)
                     /locus_tag="Smed_4548"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1035868..1035870,1035919..1035921,1036135..1036137,
                     1036171..1036173,1036180..1036182,1036210..1036212)
                     /locus_tag="Smed_4548"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1035994..1036032,1036048..1036053,1036063..1036065)
                     /locus_tag="Smed_4548"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1036316..1037083
                     /locus_tag="Smed_4549"
                     /db_xref="GeneID:5319050"
     CDS             1036316..1037083
                     /locus_tag="Smed_4549"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21138 putative amino acid uptake ABC
                     transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313282.1"
                     /db_xref="GI:150376686"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319050"
                     /translation="MTNLLEIRDLHKRYGAVEVLKGVDCSMRQGEVISIIGSSGSGKT
                     TMLRCINMLEEFQGGTIAIDGQEIGYETAGDARRRKPEREIARQRALTGMAFQQFNLF
                     PHMTAAANVMLGLVKVKKMSRDEARGLAEKWLDRVGLLSRKDHYPGQLSGGQQQRVAI
                     ARAIAMNPKLMLFDEVTSALDPELVNEVLQVIKGLADDGMSMLIVTHEMRFAYEVSSR
                     VIFMNQGRIAEEGDPREMFLKPRTERLAEFLKTSTFN"
     misc_feature    1036325..1037068
                     /locus_tag="Smed_4549"
                     /note="ABC-type polar amino acid transport system, ATPase
                     component [Amino acid transport and metabolism]; Region:
                     GlnQ; COG1126"
                     /db_xref="CDD:224051"
     misc_feature    1036328..1036996
                     /locus_tag="Smed_4549"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    1036424..1036447
                     /locus_tag="Smed_4549"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(1036433..1036438,1036442..1036450,1036604..1036606,
                     1036835..1036840,1036934..1036936)
                     /locus_tag="Smed_4549"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    1036595..1036606
                     /locus_tag="Smed_4549"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    1036763..1036792
                     /locus_tag="Smed_4549"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    1036823..1036840
                     /locus_tag="Smed_4549"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    1036847..1036858
                     /locus_tag="Smed_4549"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    1036922..1036942
                     /locus_tag="Smed_4549"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            1037118..1037501
                     /locus_tag="Smed_4550"
                     /db_xref="GeneID:5319051"
     CDS             1037118..1037501
                     /locus_tag="Smed_4550"
                     /note="PFAM: Endoribonuclease L-PSP;
                     KEGG: sme:SMb21139 putative protein, similar to
                     translation initiation inhibitors"
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease L-PSP"
                     /protein_id="YP_001313283.1"
                     /db_xref="GI:150376687"
                     /db_xref="InterPro:IPR006175"
                     /db_xref="GeneID:5319051"
                     /translation="MTIKRYGTGETGAGKQPLPFARAVEANGWLYVSGQVAMQKGEIA
                     GGGIIAESRKAIENMIAILHEAGYGLEDVVRVGVWLDDPRDFWTFNGIYAEYFGEHPP
                     ARACVQSRMMVDCKVEVDCVAYKAK"
     misc_feature    1037175..1037486
                     /locus_tag="Smed_4550"
                     /note="YjgF, YER057c, and UK114 belong to a large family
                     of proteins present in bacteria, archaea, and eukaryotes
                     with no definitive function. The conserved domain is
                     similar in structure to chorismate mutase but there is no
                     sequence similarity and no...; Region:
                     YjgF_YER057c_UK114_family; cd00448"
                     /db_xref="CDD:100004"
     misc_feature    order(1037175..1037180,1037187..1037189,1037193..1037195,
                     1037202..1037204,1037208..1037210,1037214..1037219,
                     1037331..1037333,1037337..1037342,1037346..1037348,
                     1037352..1037354,1037385..1037387,1037394..1037396,
                     1037421..1037444,1037469..1037471,1037475..1037477,
                     1037481..1037483)
                     /locus_tag="Smed_4550"
                     /note="homotrimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:100004"
     misc_feature    order(1037175..1037177,1037373..1037375,1037385..1037387,
                     1037427..1037429,1037469..1037471)
                     /locus_tag="Smed_4550"
                     /note="putative active site [active]"
                     /db_xref="CDD:100004"
     gene            1037516..1038349
                     /locus_tag="Smed_4551"
                     /db_xref="GeneID:5318413"
     CDS             1037516..1038349
                     /locus_tag="Smed_4551"
                     /note="PFAM: regulatory protein IclR; Transcriptional
                     regulator IclR;
                     KEGG: sme:SMb21140 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein IclR"
                     /protein_id="YP_001313284.1"
                     /db_xref="GI:150376688"
                     /db_xref="InterPro:IPR005471"
                     /db_xref="InterPro:IPR014757"
                     /db_xref="GeneID:5318413"
                     /translation="MSGKEDAVAYADDTINRRARGLDRAFEILDFLRVQRQPLRPNEI
                     AQGIGAPRSSVYELVNLLLRQNILEYRGDDGRVFLGRKLYFLGAAYAEQFDLMRECEH
                     LLARIAGETRETAQMCQLEGSKYAVVLMNEGSRPFRISTSIGEPVAIPWTASGRLLVD
                     HMSDEEIIAFIPPEDFVLPDGTRLEPAEFIAQVRNAKKEGYFTFNSIVDSFTHCFAVP
                     VYDAEAICIATLCLVAPKEDGLRNRDAYLRVLIDGAGELSEKLGYRNDLAASVRAASA
                     R"
     misc_feature    1037573..1038304
                     /locus_tag="Smed_4551"
                     /note="Transcriptional regulator [Transcription]; Region:
                     IclR; COG1414"
                     /db_xref="CDD:224332"
     misc_feature    1037576..1037731
                     /locus_tag="Smed_4551"
                     /note="IclR helix-turn-helix domain; Region: HTH_IclR;
                     pfam09339"
                     /db_xref="CDD:150115"
     misc_feature    1037918..1038289
                     /locus_tag="Smed_4551"
                     /note="Bacterial transcriptional regulator; Region: IclR;
                     pfam01614"
                     /db_xref="CDD:201890"
     gene            complement(1038362..1039444)
                     /locus_tag="Smed_4552"
                     /db_xref="GeneID:5318414"
     CDS             complement(1038362..1039444)
                     /locus_tag="Smed_4552"
                     /note="PFAM: ABC transporter related; Transport-associated
                     OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21216 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313285.1"
                     /db_xref="GI:150376689"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5318414"
                     /translation="MSALEIRNVRKRYGEVETLKGIDIALESGEFLVLLGSSGCGKST
                     LLNIIAGLSEPSGGDILIGERSVLGVHPKDRDIAMVFQSYALYPNLTVARNIGFGLEM
                     RRVPRAERDRAVCDTARLLQIEDLLERKPSQLSGGQRQRVAIGRALVRDPQVFLFDEP
                     LSNLDAKLRMEMRTELKRLHQMLKTTVVYVTHDQIEAMTLATRIAVMRDGRIEQLATP
                     EEIYDRPATLYVAGFVGSPPMNILDAEVTASGLKLDGCEEVLPLPAAFDGTALAGRRA
                     KVGIRPEAMRLAAESEDPRLTADIEVVELTGPELVTTATVGRQRITACLPPRTALGTG
                     SVHAFTFDETAMHLFDPESGRSLKVG"
     misc_feature    complement(1038380..1039444)
                     /locus_tag="Smed_4552"
                     /note="glycerol-3-phosphate transporter ATP-binding
                     subunit; Provisional; Region: ugpC; PRK11650"
                     /db_xref="CDD:236947"
     misc_feature    complement(1038797..1039435)
                     /locus_tag="Smed_4552"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    complement(1039316..1039339)
                     /locus_tag="Smed_4552"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(order(1038869..1038871,1038968..1038973,
                     1039199..1039201,1039313..1039321,1039325..1039330))
                     /locus_tag="Smed_4552"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1039199..1039210)
                     /locus_tag="Smed_4552"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1039016..1039045)
                     /locus_tag="Smed_4552"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1038968..1038985)
                     /locus_tag="Smed_4552"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1038950..1038961)
                     /locus_tag="Smed_4552"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1038863..1038883)
                     /locus_tag="Smed_4552"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1038398..1038613)
                     /locus_tag="Smed_4552"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            complement(1039441..1040376)
                     /locus_tag="Smed_4553"
                     /db_xref="GeneID:5318415"
     CDS             complement(1039441..1040376)
                     /locus_tag="Smed_4553"
                     /note="PFAM: PfkB domain protein;
                     KEGG: sme:SMb21217 putative sugar kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase-like domain-containing protein"
                     /protein_id="YP_001313286.1"
                     /db_xref="GI:150376690"
                     /db_xref="InterPro:IPR002173"
                     /db_xref="InterPro:IPR011611"
                     /db_xref="GeneID:5318415"
                     /translation="MRPLAAIGNVNVDLILGPAEPWPKPGTEIIVDHDELRVGGCAGN
                     NALAWESLGVDYVIAANVGNDQFGAWLKEAFGDRSRDWPVEAAGTTLSVGITHPDGER
                     TFFTTRGHLPLLSFQEVRTMLDGNRLRGGYALLSGSFLTDALSLAYDALFDWADAHEI
                     AVALDTGWPLEGWTEANRLKTLAWLKRCHCALFNEVETTTLTGQSDPAEAARSLKSEM
                     PADAIVVVKRGPNGALAIDRNGAAFSFPAPSVQVVDTIGAGDVFNAGFLAALAADMPL
                     IDCLKTGVTIASQAISTLPRRYGKPLSAFIEESRR"
     misc_feature    complement(1039453..1040370)
                     /locus_tag="Smed_4553"
                     /note="Sugar kinases, ribokinase family [Carbohydrate
                     transport and metabolism]; Region: RbsK; COG0524"
                     /db_xref="CDD:223598"
     misc_feature    complement(1039486..1040370)
                     /locus_tag="Smed_4553"
                     /note="Ribokinase-like subgroup A.  Found in bacteria and
                     archaea, this subgroup is part of the ribokinase/pfkB
                     superfamily.  Its oligomerization state is unknown at this
                     time; Region: ribokinase_group_A; cd01942"
                     /db_xref="CDD:238917"
     misc_feature    complement(order(1039597..1039599,1039606..1039608,
                     1040245..1040247))
                     /locus_tag="Smed_4553"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238917"
     misc_feature    complement(order(1039516..1039518,1039525..1039527,
                     1039591..1039593,1039600..1039605,1039612..1039614,
                     1039696..1039698,1039795..1039797))
                     /locus_tag="Smed_4553"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238917"
     gene            complement(1040379..1041398)
                     /locus_tag="Smed_4554"
                     /db_xref="GeneID:5318416"
     CDS             complement(1040379..1041398)
                     /locus_tag="Smed_4554"
                     /note="PFAM: sugar isomerase (SIS);
                     KEGG: sme:SMb21218 putative sugar-processing enzyme,
                     possibly aminotransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar isomerase (SIS)"
                     /protein_id="YP_001313287.1"
                     /db_xref="GI:150376691"
                     /db_xref="InterPro:IPR001347"
                     /db_xref="GeneID:5318416"
                     /translation="MSISKDRPAGLVAIDREMARQHGDAVASYQEAAATAQRIAASLK
                     STGRLLLLGMGGSHAVARAVEPLYRALGIDAVALPLSEQLGQPLPIEGKTILVTSQSG
                     ESAEVLRWFRETDGGTSETFGLTLEEDAFLAKAIPSLVGAGGTEQAFAATRSLTVTFA
                     LHLAILAALGADPAEALRALKTPEAPAIDGALAMLTGVSAIVTSGRRLQGIAEAIALG
                     LTELSRLPCFSLEGGQLRHGPMEMLGPSMAVILFRAADPTAGLVGAMAVSAAEAGSPV
                     VVFDASGEPPAAGATTIRFEPAAGMAAIFAMLPVAQSLMIAFADARVENAGTPVRSTK
                     VTRSE"
     misc_feature    complement(1040385..1041371)
                     /locus_tag="Smed_4554"
                     /note="Predicted phosphosugar isomerases [Cell envelope
                     biogenesis, outer membrane]; Region: AgaS; COG2222"
                     /db_xref="CDD:225132"
     misc_feature    complement(1040922..1041257)
                     /locus_tag="Smed_4554"
                     /note="SIS domain. SIS (Sugar ISomerase) domains are found
                     in many phosphosugar isomerases and phosphosugar binding
                     proteins. SIS domains are also found in proteins that
                     regulate the expression of genes involved in synthesis of
                     phosphosugars; Region: SIS; cl00389"
                     /db_xref="CDD:241833"
     misc_feature    complement(1040388..1040816)
                     /locus_tag="Smed_4554"
                     /note="SIS domain. SIS (Sugar ISomerase) domains are found
                     in many phosphosugar isomerases and phosphosugar binding
                     proteins. SIS domains are also found in proteins that
                     regulate the expression of genes involved in synthesis of
                     phosphosugars; Region: SIS; cl00389"
                     /db_xref="CDD:241833"
     gene            complement(1041401..1042246)
                     /locus_tag="Smed_4555"
                     /db_xref="GeneID:5318417"
     CDS             complement(1041401..1042246)
                     /locus_tag="Smed_4555"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21219 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313288.1"
                     /db_xref="GI:150376692"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318417"
                     /translation="MERQSPLFSVFIHASALVLAIVVLAPVAWLFIMSISPAADLSAK
                     PLAWWPSEIDLSRYRTLLSAVENSAGAAFIASLLNSLKVAGMATLAAVVVAVPAAWAV
                     SRTPSVSWSFYVVIATYMLPPVALAVPLYMGLAHFGLLNSVFGLALVYLTILAPFTTW
                     LLKSGFDTIPREIESAAMIDGARLDHILRLLTLPLAAPVMATSALFAFLLAWDEFFYA
                     LLFTSDQRAKTLTVAIADLAGGRVSDYGLIATAGVLAALPPVLVGLVMQRALISGLTS
                     GGVKG"
     sig_peptide     complement(1042127..1042246)
                     /locus_tag="Smed_4555"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.761) with cleavage site probability 0.445 at
                     residue 40"
     misc_feature    complement(1041407..1042156)
                     /locus_tag="Smed_4555"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    complement(1041503..1041940)
                     /locus_tag="Smed_4555"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1041503..1041505,1041512..1041517,
                     1041545..1041550,1041587..1041592,1041599..1041610,
                     1041629..1041631,1041638..1041643,1041683..1041685,
                     1041734..1041736,1041743..1041748,1041758..1041760,
                     1041764..1041769,1041776..1041778,1041782..1041784,
                     1041854..1041856,1041860..1041865,1041872..1041901,
                     1041905..1041916))
                     /locus_tag="Smed_4555"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1041593..1041610,1041854..1041898))
                     /locus_tag="Smed_4555"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1041515..1041517,1041545..1041547,
                     1041554..1041556,1041590..1041592,1041794..1041796,
                     1041854..1041856))
                     /locus_tag="Smed_4555"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1041662..1041664,1041674..1041679,
                     1041695..1041733))
                     /locus_tag="Smed_4555"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1042246..1043127)
                     /locus_tag="Smed_4556"
                     /db_xref="GeneID:5318418"
     CDS             complement(1042246..1043127)
                     /locus_tag="Smed_4556"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21220 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313289.1"
                     /db_xref="GI:150376693"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318418"
                     /translation="MTGTWISTRAWLLMLPLLVVMTAVIGWPLIDTVRLSFTDAKLIG
                     TEGGFVGVDNYARMLTGSNFQRALITTTWFAVISVAAEMVLGVLAALLLNQKFRGRTA
                     LRALMILPWALPTVVNATLWRLIYNPEYGALNAGLTQIGILDSYRSWLGEPGTALAAL
                     IVADCWKNFPLVALIALAALQAVPRDINAASIVDGAGPFNRFRFVILPYLAGPLLVAL
                     VLRTIEAFKVFDIIWVMTRGGPANSTRTLSILVYQEAFSFQRAGSGASLALIVTLLVT
                     ILAVAYAALLRKAAGAS"
     sig_peptide     complement(1043047..1043127)
                     /locus_tag="Smed_4556"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.850) with cleavage site probability 0.820 at
                     residue 27"
     misc_feature    complement(1042354..1042926)
                     /locus_tag="Smed_4556"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1042381..1042386,1042426..1042431,
                     1042438..1042449,1042468..1042470,1042477..1042482,
                     1042522..1042524,1042573..1042575,1042582..1042587,
                     1042597..1042599,1042603..1042608,1042615..1042617,
                     1042621..1042623,1042630..1042635,1042708..1042710,
                     1042714..1042719,1042777..1042806,1042810..1042821,
                     1042846..1042848,1042861..1042866,1042873..1042878))
                     /locus_tag="Smed_4556"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1042432..1042449,1042708..1042725,
                     1042777..1042803))
                     /locus_tag="Smed_4556"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1042381..1042383,1042390..1042392,
                     1042429..1042431,1042648..1042650,1042708..1042710))
                     /locus_tag="Smed_4556"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1042501..1042503,1042513..1042518,
                     1042534..1042572))
                     /locus_tag="Smed_4556"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1043256..1044494)
                     /locus_tag="Smed_4557"
                     /db_xref="GeneID:5318419"
     CDS             complement(1043256..1044494)
                     /locus_tag="Smed_4557"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb21221 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313290.1"
                     /db_xref="GI:150376694"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5318419"
                     /translation="MSKSIRNALIGATLVGAGFTGHAQAETTLNALFMAQAAYSEADV
                     RAMTDAFAKANPDIKVNLEFVPYEGLHDKTVLAQGSGGGYDVVLFDVIWPAEYAANNV
                     LLDVTDRITDEINQGVLPGAWTTVEYDGKRYGMPWILDTKYLFYNKEILEKAGIKEPP
                     KTWDELAEQAKAIKDKGLLENPIAWSWSQAEAAICDYTTLVSAYGGKFLDSGKPAFAS
                     GGGLDALNYMVTSYTSGLTNPNSKEFLEEDVRKVFQNGEAAFALNWTYMYNLANDPKE
                     SKVAGKVGVVPAPGVEGKSEVSAVNGSMGLGITTTSKHPEEAWKYIVHMTSQETQNAY
                     AKLSLPIWASSYEDPDVTKGQEELIAAAKRGLAAMYPRPTTPKYQELSAALQQAIQEA
                     LLGQASAEDALKSAAENSGL"
     sig_peptide     complement(1044417..1044494)
                     /locus_tag="Smed_4557"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.911 at
                     residue 26"
     misc_feature    complement(1043502..1044362)
                     /locus_tag="Smed_4557"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     misc_feature    complement(1043436..1044359)
                     /locus_tag="Smed_4557"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_8; pfam13416"
                     /db_xref="CDD:222114"
     gene            1044718..1045947
                     /locus_tag="Smed_4558"
                     /db_xref="GeneID:5318420"
     CDS             1044718..1045947
                     /locus_tag="Smed_4558"
                     /note="PFAM: ROK family protein;
                     KEGG: sme:SMb21222 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="YP_001313291.1"
                     /db_xref="GI:150376695"
                     /db_xref="InterPro:IPR000600"
                     /db_xref="GeneID:5318420"
                     /translation="MNEIRPVRAKSGTNQEGASAHNRRVMIDALRLNGHLSRADLARA
                     TALTKQAVSNIIEELENDGLVASLAAVRKGRGQPSTPYRLVPEGAFAIGLQIDRHVTR
                     TIAVDLIGAVLIRKEVNLPGGGPEEGVDAILALIDETRRELVTTAPEFNDRLVGLGVA
                     MPGPFGIDSATDDPWMMAAWQSFPLLERLSEGTGLDVRLQNDAAAAATAEKMVGAAHG
                     IDHAVCVYLGYGLGAGLILNGELYRGGHGNAGEIGMILSRARVGADDARAPIEHRISI
                     ASLCKGLDIDPADPDLYRRIDAAAGSKDRRVMDWIAGAAHELRATIQLLETIFDPQTI
                     ILCGGMPPVLANLLIDALHPLLPSIAERRQRSTPRLQLGFTDPWAVAVGAAAEPISRT
                     FDPRFSAILKSRVGGTL"
     misc_feature    1044781..1044951
                     /locus_tag="Smed_4558"
                     /note="helix_turn_helix, cAMP Regulatory protein
                     C-terminus; DNA binding domain of prokaryotic regulatory
                     proteins belonging to the catabolite activator protein
                     family; Region: HTH_CRP; cd00092"
                     /db_xref="CDD:238044"
     misc_feature    order(1044820..1044822,1044826..1044834,1044859..1044861)
                     /locus_tag="Smed_4558"
                     /note="non-specific DNA interactions [nucleotide binding];
                     other site"
                     /db_xref="CDD:238044"
     misc_feature    1044859..1044879
                     /locus_tag="Smed_4558"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238044"
     misc_feature    order(1044862..1044867,1044877..1044879)
                     /locus_tag="Smed_4558"
                     /note="sequence specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238044"
     misc_feature    1044862..1044867
                     /locus_tag="Smed_4558"
                     /note="putative cAMP binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238044"
     misc_feature    1044967..1045911
                     /locus_tag="Smed_4558"
                     /note="Transcriptional regulator/sugar kinase
                     [Transcription / Carbohydrate transport and metabolism];
                     Region: NagC; COG1940"
                     /db_xref="CDD:224851"
     misc_feature    1044994..1045485
                     /locus_tag="Smed_4558"
                     /note="Nucleotide-Binding Domain of the sugar
                     kinase/HSP70/actin superfamily; Region:
                     NBD_sugar-kinase_HSP70_actin; cl17037"
                     /db_xref="CDD:247684"
     gene            1046157..1047056
                     /locus_tag="Smed_4559"
                     /db_xref="GeneID:5318421"
     CDS             1046157..1047056
                     /locus_tag="Smed_4559"
                     /EC_number="2.7.7.4"
                     /note="with CysN catalyzes the formation of
                     adenylylsulfate from sulfate and ATP"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit 2"
                     /protein_id="YP_001313292.1"
                     /db_xref="GI:150376696"
                     /db_xref="InterPro:IPR002500"
                     /db_xref="InterPro:IPR011784"
                     /db_xref="GeneID:5318421"
                     /translation="MSLPHLRRLEAEAIHVIREVVATFSNPVALYSIGKDSSVLLHLA
                     MKAFYPGKPPFPFLHVDTKWKFREMIEFRDRMARELGFDLLVHVNQDGIDQGIGPFTH
                     GSNVHTHVMKTMGLRQALEKYGFDAALAGARRDEEKSRAKERIFSIRSAQHGWDPKRQ
                     RPEMWKTYNTRVAPGETMRVFPLSNWTEFDIWQYILREDIPIVPLYFAAWRPVVKRDG
                     TLIMVDDERMPIQPGEEVLEHQVRFRTLGCYPLTGAVESEAATVPDILREMLTVRTSE
                     RQSRLIDSDEVGAMEKKKREGYF"
     misc_feature    1046172..1047053
                     /locus_tag="Smed_4559"
                     /note="sulfate adenylyltransferase, small subunit; Region:
                     CysD; TIGR02039"
                     /db_xref="CDD:131094"
     misc_feature    1046232..1046798
                     /locus_tag="Smed_4559"
                     /note="This domain is found in phosphoadenosine
                     phosphosulphate (PAPS) reductase enzymes or PAPS
                     sulphotransferase. PAPS reductase is part of the adenine
                     nucleotide alpha hydrolases superfamily also including N
                     type ATP PPases and ATP sulphurylases. A highly...;
                     Region: PAPS_reductase; cd01713"
                     /db_xref="CDD:238846"
     misc_feature    order(1046490..1046492,1046574..1046576,1046679..1046681,
                     1046691..1046693)
                     /locus_tag="Smed_4559"
                     /note="Active Sites [active]"
                     /db_xref="CDD:238846"
     gene            1047056..1048957
                     /locus_tag="Smed_4560"
                     /db_xref="GeneID:5318422"
     CDS             1047056..1048957
                     /locus_tag="Smed_4560"
                     /EC_number="2.7.1.25"
                     /EC_number="2.7.7.4"
                     /note="in Rhizobium meliloti this protein is involved in
                     the synthesis of nodulation factors that are active on the
                     roots of alfalfa; catalyzes formation of activated sulfate
                     intermediate; converts ATP and sulfate to diphosphate and
                     adenylylsulfate and then ATP and adenylyl sulfate to ADP
                     and 3'-phosphoadenylyl sulfate; the activated intermediate
                     is transferred to the nodulation factors by NodH; may
                     interact with NodP and NodQ; similar to the CysD and CysN
                     proteins from EScherichia coli involved in cysteine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional sulfate adenylyltransferase subunit
                     1/adenylylsulfate kinase"
                     /protein_id="YP_001313293.1"
                     /db_xref="GI:150376697"
                     /db_xref="InterPro:IPR000795"
                     /db_xref="InterPro:IPR002891"
                     /db_xref="InterPro:IPR004161"
                     /db_xref="InterPro:IPR005225"
                     /db_xref="InterPro:IPR011779"
                     /db_xref="GeneID:5318422"
                     /translation="MSYVQSIPPHDIEAHLVEHDNKSILRFITCGSVDDGKSTLIGRL
                     LYDAKLIFEDQLANLGRVGSPGAANGKEIDLALLLDGLEAEREQGITIDVAYRYFATS
                     KRKFIVADTPGHEEYTRNMVTGASTADLAIILIDSRQGILQQTRRHSYIASLLGIRHV
                     VLAVNKIDLVDFRQQVYDEIVADYMAFAKELGFASIRPIPISARDGDNVISASPNTPW
                     YRGAALLEYLETVELEPMDQAKPFRFPVQMVMRPNADFRGYAGQISCGRISVGDPVVV
                     AKTGQRTSVKAIVTYDGDLATAGEGEAVTLVLSDEVDASRGNMLVAPGARPFVADQFQ
                     AHVIWFDASPMMPGRSYILRTETDSVSATVTALKHQVNINSFVREAAKSLQMNEVGVC
                     NISTQTPIAFDAYTDNRATGNFIIVDRVTNATVGAGLIDFPLRRADNVHWHALEVNKV
                     ARSAMKNQLPAVLWFTGLSGSGKSTIANELDRILHAQGKHTYLLDGDNVRHGLNRDLG
                     FTEEDRVENIRRVAEVAKLMADAGLIVLVSFISPFRDERRMARELMDDGEFIEIFVDT
                     PIEECARRDPKGLYEKALAGKIANFTGVSSPYETPENPELHIRTVGHEPTDLALAIEE
                     FLDRRMEGK"
     misc_feature    1047056..1048945
                     /locus_tag="Smed_4560"
                     /note="bifunctional sulfate adenylyltransferase subunit
                     1/adenylylsulfate kinase protein; Provisional; Region:
                     PRK05506"
                     /db_xref="CDD:180120"
     misc_feature    1047131..1047760
                     /locus_tag="Smed_4560"
                     /note="CysN, together with protein CysD, forms the ATP
                     sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166"
                     /db_xref="CDD:206729"
     misc_feature    order(1047131..1047133,1047332..1047337,1047341..1047343,
                     1047347..1047349,1047368..1047370,1047374..1047376,
                     1047422..1047424,1047431..1047433)
                     /locus_tag="Smed_4560"
                     /note="CysD dimerization site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:206729"
     misc_feature    1047146..1047169
                     /locus_tag="Smed_4560"
                     /note="G1 box; other site"
                     /db_xref="CDD:206729"
     misc_feature    order(1047149..1047151,1047155..1047157,1047167..1047172,
                     1047179..1047181,1047188..1047193,1047338..1047343,
                     1047395..1047400,1047467..1047472,1047590..1047592,
                     1047602..1047604)
                     /locus_tag="Smed_4560"
                     /note="putative GEF interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:206729"
     misc_feature    order(1047155..1047157,1047161..1047172,1047302..1047304,
                     1047548..1047553,1047557..1047562,1047659..1047667)
                     /locus_tag="Smed_4560"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206729"
     misc_feature    1047308..1047340
                     /locus_tag="Smed_4560"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206729"
     misc_feature    1047326..1047328
                     /locus_tag="Smed_4560"
                     /note="G2 box; other site"
                     /db_xref="CDD:206729"
     misc_feature    1047383..1047394
                     /locus_tag="Smed_4560"
                     /note="G3 box; other site"
                     /db_xref="CDD:206729"
     misc_feature    1047389..1047445
                     /locus_tag="Smed_4560"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206729"
     misc_feature    1047548..1047559
                     /locus_tag="Smed_4560"
                     /note="G4 box; other site"
                     /db_xref="CDD:206729"
     misc_feature    1047659..1047667
                     /locus_tag="Smed_4560"
                     /note="G5 box; other site"
                     /db_xref="CDD:206729"
     misc_feature    1047779..1048021
                     /locus_tag="Smed_4560"
                     /note="CysN_NodQ_II: This subfamily represents the domain
                     II of the large subunit of ATP sulfurylase (ATPS): CysN or
                     the N-terminal portion of NodQ, found mainly in
                     proteobacteria and homologous to the domain II of EF-Tu.
                     Escherichia coli ATPS consists of CysN...; Region:
                     CysN_NodQ_II; cd03695"
                     /db_xref="CDD:239666"
     misc_feature    1048040..1048345
                     /locus_tag="Smed_4560"
                     /note="TCysN_NoDQ_II: This subfamily represents the domain
                     II of the large subunit of ATP sulfurylase (ATPS): CysN or
                     the N-terminal portion of NodQ, found mainly in
                     proteobacteria and homologous to the domain II of EF-Tu.
                     Escherichia coli ATPS consists of CysN...; Region:
                     CysN_NoDQ_III; cd04095"
                     /db_xref="CDD:239762"
     misc_feature    1048439..1048885
                     /locus_tag="Smed_4560"
                     /note="Adenosine 5&apos;-phosphosulfate kinase (APSK)
                     catalyzes the phosphorylation of adenosine
                     5&apos;-phosphosulfate to form 3&apos;-phosphoadenosine
                     5&apos;-phosphosulfate (PAPS). The end-product PAPS is a
                     biologically &quot;activated&quot; sulfate form...;
                     Region: APSK; cd02027"
                     /db_xref="CDD:238985"
     misc_feature    order(1048460..1048465,1048469..1048480,1048553..1048555,
                     1048580..1048582,1048595..1048597,1048604..1048606,
                     1048673..1048681,1048775..1048777,1048826..1048831)
                     /locus_tag="Smed_4560"
                     /note="ligand-binding site [chemical binding]; other site"
                     /db_xref="CDD:238985"
     gene            1048954..1049793
                     /locus_tag="Smed_4561"
                     /db_xref="GeneID:5319229"
     CDS             1048954..1049793
                     /locus_tag="Smed_4561"
                     /note="TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase;
                     PFAM: inositol monophosphatase;
                     KEGG: sme:SMb21225 putative inositol monophosphatase,
                     possibly involved in PAPS metabolism protein"
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase"
                     /protein_id="YP_001313294.1"
                     /db_xref="GI:150376698"
                     /db_xref="InterPro:IPR000760"
                     /db_xref="InterPro:IPR006240"
                     /db_xref="GeneID:5319229"
                     /translation="MTPLCQIFEHIALEAGAAILEVYDAGPEVCYKDDQSPVTEADER
                     AEAIILERLAAAFPGIPVVAEESVCSGRVPDISGGSFFLVDPLDGTKEFINRRSDFTV
                     NIALIKGNVPVAGIVYAPAQRCAYVADGGRAEKLLLDKLWALEHRQPIRVRMRGAELT
                     AVASRSHNSSETEAFLTGHGVMNYASVGSSLKFCLLAEGKADVYPRFGRTMEWDTAAG
                     DAVLRAAGGSVVRLDGSRLLYGKTMQDEDSDFANPHFIAWADMSPVHLTAAEGVGAAH
                     ALT"
     misc_feature    1048954..1049679
                     /locus_tag="Smed_4561"
                     /note="Archaeal fructose-1,6-bisphosphatase and related
                     enzymes of inositol monophosphatase family [Carbohydrate
                     transport and metabolism]; Region: SuhB; COG0483"
                     /db_xref="CDD:223559"
     misc_feature    1048963..1049724
                     /locus_tag="Smed_4561"
                     /note="CysQ, a
                     3&apos;-Phosphoadenosine-5&apos;-phosphosulfate (PAPS)
                     3&apos;-phosphatase, is a bacterial member of the inositol
                     monophosphatase family. It has been proposed that CysQ
                     helps control intracellular levels of PAPS, which is an
                     intermediate in...; Region: CysQ; cd01638"
                     /db_xref="CDD:238816"
     misc_feature    order(1049077..1049079,1049146..1049151,1049206..1049223,
                     1049227..1049229,1049443..1049445,1049452..1049454,
                     1049527..1049529,1049563..1049565,1049590..1049595)
                     /locus_tag="Smed_4561"
                     /note="active site"
                     /db_xref="CDD:238816"
     gene            1049841..1050581
                     /locus_tag="Smed_4562"
                     /db_xref="GeneID:5319230"
     CDS             1049841..1050581
                     /locus_tag="Smed_4562"
                     /note="PFAM: PHP domain protein;
                     SMART: phosphoesterase PHP domain protein;
                     KEGG: sme:SMb21226 putative histidinol phosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase domain-containing protein"
                     /protein_id="YP_001313295.1"
                     /db_xref="GI:150376699"
                     /db_xref="InterPro:IPR003141"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="GeneID:5319230"
                     /translation="MNGQESICTSRPVFHRYRDLSRARLNVELQVHTSWTDGQATALE
                     ILQTAKERGLAALAFTEHVREDTTWFPRFREEVLSAARGFDDISVYVGCETKAMDEDG
                     RLDVSQDVLDRCDIVLGVVHRFPDGRGGYLDFEQLSYEKTADLEFRLSMGMVKNAPID
                     VLAHPGGMSLRRHGRFPEACFRDMMTATLERQIAIEINSSYLVDMPAFLALCEEVNPF
                     VSIGSDAHRLSELGHCRDQLLELGAGQS"
     misc_feature    1049919..1050437
                     /locus_tag="Smed_4562"
                     /note="PHP domain; Region: PHP; pfam02811"
                     /db_xref="CDD:217238"
     misc_feature    1049970..1050560
                     /locus_tag="Smed_4562"
                     /note="Polymerase and Histidinol Phosphatase domain;
                     Region: PHP; cl17102"
                     /db_xref="CDD:214263"
     misc_feature    order(1050024..1050026,1050120..1050122,1050510..1050512,
                     1050516..1050518)
                     /locus_tag="Smed_4562"
                     /note="active site"
                     /db_xref="CDD:213985"
     gene            1050578..1051570
                     /locus_tag="Smed_4563"
                     /db_xref="GeneID:5319231"
     CDS             1050578..1051570
                     /locus_tag="Smed_4563"
                     /EC_number="6.3.5.5"
                     /note="undetermined role; similar to CarB protein but much
                     smaller"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase-like protein"
                     /protein_id="YP_001313296.1"
                     /db_xref="GI:150376700"
                     /db_xref="InterPro:IPR003806"
                     /db_xref="InterPro:IPR011761"
                     /db_xref="GeneID:5319231"
                     /translation="MKVFITGAGALLGQGIIRALRRSTLNARIIVGDPSPLSAGLYWG
                     DAAYLVPMAKDPSYLDRLGELLRAERPEVLIPGTDVELPILAANRDAIERTYGTKVII
                     SSPRVVSIANDKWLTSEFFRERGLGYVPSCLPGDEDALIEECGFPLIVKPRVGARSIG
                     FSVVRNREQLMRAIEEQPGIVIQKYVGAETTEYTAGTLTFDGKCRATIVMRRDLRDGN
                     TYRAFAEPFPALNKAMAEAADALGAYGPANFQFRLDDGVPRIFEINARFSGTTAVRIH
                     AGFNEVEMCIRHLLFEEPVEQPQITPVTILRHWSETVVKPGELVTASSKLDETV"
     misc_feature    1050578..1051543
                     /locus_tag="Smed_4563"
                     /note="carbamoyl phosphate synthase-like protein;
                     Provisional; Region: PRK12767"
                     /db_xref="CDD:237195"
     misc_feature    1050908..1051384
                     /locus_tag="Smed_4563"
                     /note="ATP-grasp domain; Region: ATP-grasp_4; pfam13535"
                     /db_xref="CDD:222206"
     gene            1051576..1052502
                     /locus_tag="Smed_4564"
                     /db_xref="GeneID:5319232"
     CDS             1051576..1052502
                     /locus_tag="Smed_4564"
                     /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase;
                     dTDP-4-dehydrorhamnose reductase; Male sterility domain;
                     KEGG: sme:SMb21228 putative nucleotide sugar epimerase
                     dehydratase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="YP_001313297.1"
                     /db_xref="GI:150376701"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5319232"
                     /translation="MRLVVTGATGFVGARVIDRALSRGYEVTALARDPERIATRKGSG
                     LRVEQWTVGDPLPPLGRSDAVLHLAAHIPADLSDPREASRCFEVNTNGALEVAMQAAL
                     QGVSRFVQFGSAQVYAPGTGPASETSPAFPVHRASYYLASKLAAEICLLAFGKASAMP
                     VTVLRLASVYGPGMHDAGMVPTFVRTLGRRGSLIIQDGGRYTVDLVYVDDVVSLALEA
                     AERAEGGVFNAGSGRACTSLEAARIVADAVGAEQHLIAVQGGSIDAPPPGFRALDVSK
                     AIDGLNYAPLSFREGIEAWRTMTGLTDFQDGA"
     misc_feature    1051576..1052457
                     /locus_tag="Smed_4564"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    1051588..1052175
                     /locus_tag="Smed_4564"
                     /note="extended (e) SDRs; Region: SDR_e; cd08946"
                     /db_xref="CDD:212494"
     misc_feature    order(1051594..1051596,1051600..1051611,1051753..1051761,
                     1051777..1051785,1051837..1051839,1051906..1051914,
                     1051990..1051992,1052002..1052004,1052071..1052082)
                     /locus_tag="Smed_4564"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:212494"
     misc_feature    order(1051840..1051842,1051912..1051914,1051990..1051992,
                     1052002..1052004)
                     /locus_tag="Smed_4564"
                     /note="active site"
                     /db_xref="CDD:212494"
     misc_feature    order(1051912..1051914,1051990..1051992,1052077..1052079,
                     1052122..1052124,1052158..1052160)
                     /locus_tag="Smed_4564"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212494"
     gene            complement(1052572..1053735)
                     /locus_tag="Smed_4565"
                     /db_xref="GeneID:5319233"
     CDS             complement(1052572..1053735)
                     /locus_tag="Smed_4565"
                     /note="PFAM: Hemolysin-type calcium-binding region;
                     KEGG: sme:SMb21229 putative calcium-binding exported
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Hemolysin-type calcium-binding protein"
                     /protein_id="YP_001313298.1"
                     /db_xref="GI:150376702"
                     /db_xref="InterPro:IPR001343"
                     /db_xref="GeneID:5319233"
                     /translation="MILKGTNLSDTINGALGNDELWGYAGDDHLDGGDGNDKIFGGDG
                     NDFIVGGLGDDYAEGGAGNDRFNGGLGHDTLKGGLGNDIFDGGDGSDVLDGGDGHDQI
                     LGGRGHDKIFGGAGEEYIDAGDGDDIIYAGSGDDGFNNRVNPATGQVTQQAVSGGAGH
                     DKIYGEDGNDALKGQSGNDWVYGGIGNDIVDGGDGNNYLDGGEGNDVLDSEGGIDEAH
                     GGSGNDKVVVGAGDDRVFGEDGDDMLYGEAGNDTLSGGNNYDRIFGGDGNDTLRGDAG
                     QDVLVGEAGSDILWGGTESDRFVFKGAVALSGQDTVMDFQDGVDFLVIEKLGIKQYSS
                     SGAAGTVYAYDATGGDVLVKGYDAAGTAFSILVDDPNGTLSAANFSSSDFLFA"
     misc_feature    complement(<1053484..>1053618)
                     /locus_tag="Smed_4565"
                     /note="Peptidase M10 serralysin C terminal; Region:
                     Peptidase_M10_C; pfam08548"
                     /db_xref="CDD:117125"
     misc_feature    complement(1052632..>1052973)
                     /locus_tag="Smed_4565"
                     /note="Peptidase M10 serralysin C terminal; Region:
                     Peptidase_M10_C; pfam08548"
                     /db_xref="CDD:117125"
     gene            complement(1053994..1055109)
                     /locus_tag="Smed_4566"
                     /db_xref="GeneID:5319234"
     CDS             complement(1053994..1055109)
                     /locus_tag="Smed_4566"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21230 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313299.1"
                     /db_xref="GI:150376703"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5319234"
                     /translation="MRRNAANTGNPMIMHVITNFTASAGAETMLARLLHGSTDERIIV
                     VSLIGVSDRNRRLADNPRVSYVSLAAASLTALPGAILRLATLIRKERPDVILCWMYHA
                     MVAGSLAAGLARHGAPVFWNVRQSLDDPASLTRSSRVAIAAAKLLSRRPTGIIYNSAR
                     ALDLHRAYGYTNQNAVVIPNGFELPELAAPEPRAARRIGIVGRFHPQKDHGTFFKAAA
                     QVLKTHPQAVFSAAGNGLVCDNPEVMELIAKAGLPAHAVDLRGEVSDMPAFYRSIDLL
                     VLSSRTEGFPNVIAEAMSYGKPIVTTDVGDAAVVAGRAGIAVPPRNPQALAEAMRAFL
                     DLSEAEYARYARTARERIENEYALAAVSAKYSKFLTA"
     misc_feature    complement(1054006..1055073)
                     /locus_tag="Smed_4566"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. WbnK in Shigella
                     dysenteriae has been shown to be involved in the type 7
                     O-antigen biosynthesis; Region: GT1_WbnK_like; cd03807"
                     /db_xref="CDD:99979"
     misc_feature    complement(1054567..1055073)
                     /locus_tag="Smed_4566"
                     /note="Glycosyltransferase Family 4; Region:
                     Glyco_transf_4; pfam13439"
                     /db_xref="CDD:222130"
     misc_feature    complement(order(1054246..1054248,1054312..1054314,
                     1054501..1054509,1055035..1055037))
                     /locus_tag="Smed_4566"
                     /note="putative ADP-binding pocket [chemical binding];
                     other site"
                     /db_xref="CDD:99979"
     gene            complement(1055119..1056345)
                     /locus_tag="Smed_4567"
                     /db_xref="GeneID:5319235"
     CDS             complement(1055119..1056345)
                     /locus_tag="Smed_4567"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21231 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313300.1"
                     /db_xref="GI:150376704"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5319235"
                     /translation="MTLVEKVPRAEAEHIAEGSAGRGSAARFPQQKRVIAVVASLTAS
                     LVIFRLELLKRLVAAGHDVIAFAPEHDARVEQELAQIGVRFIRIPMARTGLNPLEDLR
                     TFWALRRHFARLKPDIVLPYTMKPIIYAGIAARTLGIRERCFLVTGLGHIFSEAAGAS
                     LKAKAIRHLCVRLYRTALRGARVVFVYNDADENDIRRYRMLSGHLSPTMISGSGVDLD
                     HFAFSTPPRGGPTFLMVARLLRDKGVVEYVEAARIVRRSFPNARFQLLGHFDSNPTAI
                     SREEIDAWGREGILDYLGTTVDVRPYLAACNAFVLPSYYREGIPRSILEALATGRPVI
                     TTDLPGCRDTVQPGKNGLVVKARDVAALAEAMTTVAKNPDLAEEMGRRSRELAETRFD
                     VHMINRMLFDGMHLTD"
     misc_feature    complement(1055140..1056243)
                     /locus_tag="Smed_4567"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. cap1E in Streptococcus
                     pneumoniae is required for the synthesis of type 1
                     capsular polysaccharides; Region: GT1_cap1E_like; cd03808"
                     /db_xref="CDD:99980"
     misc_feature    complement(1055140..1056219)
                     /locus_tag="Smed_4567"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    complement(order(1055380..1055382,1055449..1055451,
                     1055635..1055643,1056166..1056168))
                     /locus_tag="Smed_4567"
                     /note="putative ADP-binding pocket [chemical binding];
                     other site"
                     /db_xref="CDD:99980"
     gene            complement(1056505..1058700)
                     /locus_tag="Smed_4568"
                     /db_xref="GeneID:5319236"
     CDS             complement(1056505..1058700)
                     /locus_tag="Smed_4568"
                     /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase; polysaccharide
                     biosynthesis protein CapD; dTDP-4-dehydrorhamnose
                     reductase;
                     KEGG: sme:SMb21232 putative nucleotide sugar epimerase
                     dehydratase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein CapD"
                     /protein_id="YP_001313301.1"
                     /db_xref="GI:150376705"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="GeneID:5319236"
                     /translation="MQRIHAAAKAVRNHFLMLPSIRGREWRNRASAGMLWAFCGAALD
                     IGFRRIRGAVRSVQKYPALYLTDLASVGVALTMALLLRYGPGELSARPETASVLLWSG
                     AQYLAICAFVFPLSGLYSRNWKYGSISDLFTILRAVLLTSLLLVTLLFFSTRLTDIPR
                     TVVPMQSLLLIAFLAAARLSFRAEELSLRRPVFKSGRNKDAQGDDRIPLLLVGASDAA
                     DLYLRALARDPNATYVPVACLDRSEDQIGMSLRGVPIAGRIQDFEQVVAELQLLNKQP
                     RHIVFTEAPAAFGEEASDALLRSAERLGIAVSRLSQMTELKRAKGDNPYELRSIELTD
                     LLERPQAALDREAIDRLVRGRRVLITGAGGSIGSELTTQVAACDPAEIVLIDNTEYNL
                     YAIDMTLTESFPEVPRSSYLCSVRRSQRVAEIFERHRPELVFHAAALKHVPMVQLNPC
                     EGVLTNVVGTMNVANAAKKYGTLAMVQVSTDKVVNSTSVMGATKRLAELYCQALDLHG
                     LETGLGPRFMTVRFGNVLGSSGSLIPLFKRQLARGGPLTVTDANMTRFFMTIREAVEL
                     TLQASAYGFEKQLGQGEIFVLDMGEPIKIIDIARRMIRLAGFTPDQEIEIKIIGCRPG
                     EKLFEELFDETDKRISSPVPGVLGAVPEAIPLPTLRDAFARLQRHSERGNEAAVVSVM
                     RELLPRYEHEADLKMAVRNRASLRPKNRVKAKAGKSEASYGAELRSPGS"
     misc_feature    complement(1056604..1058517)
                     /locus_tag="Smed_4568"
                     /note="Predicted nucleoside-diphosphate sugar epimerases
                     [Cell envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: COG1086"
                     /db_xref="CDD:224011"
     misc_feature    complement(1056799..1057641)
                     /locus_tag="Smed_4568"
                     /note="UDP-Glcnac (UDP-linked N-acetylglucosamine)
                     inverting 4,6-dehydratase, extended (e) SDRs; Region:
                     UDP_invert_4-6DH_SDR_e; cd05237"
                     /db_xref="CDD:187548"
     misc_feature    complement(order(1057114..1057119,1057126..1057137,
                     1057219..1057221,1057267..1057269,1057336..1057338,
                     1057381..1057383,1057387..1057395,1057456..1057464,
                     1057540..1057545,1057603..1057614,1057618..1057620))
                     /locus_tag="Smed_4568"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187548"
     misc_feature    complement(order(1057096..1057098,1057111..1057116,
                     1057339..1057341,1057348..1057350,1057357..1057359,
                     1057369..1057371,1057378..1057389,1057441..1057443,
                     1057450..1057452,1057459..1057470,1057510..1057512,
                     1057522..1057524,1057534..1057536,1057540..1057542))
                     /locus_tag="Smed_4568"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187548"
     misc_feature    complement(order(1056826..1056828,1056835..1056837,
                     1056916..1056918,1057036..1057038,1057042..1057044,
                     1057054..1057062,1057093..1057098,1057105..1057113,
                     1057129..1057134,1057231..1057233,1057255..1057263,
                     1057381..1057383))
                     /locus_tag="Smed_4568"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187548"
     misc_feature    complement(order(1057219..1057221,1057231..1057233,
                     1057261..1057263,1057333..1057335))
                     /locus_tag="Smed_4568"
                     /note="active site"
                     /db_xref="CDD:187548"
     gene            complement(1059069..1059983)
                     /locus_tag="Smed_4569"
                     /db_xref="GeneID:5319237"
     CDS             complement(1059069..1059983)
                     /locus_tag="Smed_4569"
                     /note="PFAM: formyl transferase domain protein;
                     KEGG: sme:SMb21235 putative formyltransferase, similar to
                     methionyl-tRNA(fMet) N-formyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="formyl transferase domain-containing protein"
                     /protein_id="YP_001313302.1"
                     /db_xref="GI:150376706"
                     /db_xref="InterPro:IPR002376"
                     /db_xref="InterPro:IPR005793"
                     /db_xref="GeneID:5319237"
                     /translation="MRIVFVGAVESSKIALEALIKAGRPPALVITLPPEAAGRHSDFV
                     DLGNLALAAGSAVHHSTDINAPETLEAVTAVAPDLTLVIGWSQVCRRPFREIARVGTA
                     GFHPAALPRLRGRGVIPWTILRGEEKTGSTLFWLDDGVDSGPILLQRQFPVDPDETAR
                     SLYTKHTENLAQMIVEAAAQVEAGNAARAEQNQAEASYCAKRTAEDGLIDWRQSAASI
                     LRLIRAVGAPYPGAFTFYNGQKIRIDAAVPVENSSRFIGLTGQIQAITERGFIVLCGD
                     AECIEATSWKWASERRPPIHGKLGGTAA"
     misc_feature    complement(1059078..1059983)
                     /locus_tag="Smed_4569"
                     /note="Methionyl-tRNA formyltransferase [Translation,
                     ribosomal structure and biogenesis]; Region: Fmt; COG0223"
                     /db_xref="CDD:223301"
     misc_feature    complement(1059459..1059980)
                     /locus_tag="Smed_4569"
                     /note="Formyl transferase catalytic core domain found in a
                     group of proteins with unknown functions; Region:
                     FMT_core_like_4; cd08651"
                     /db_xref="CDD:187720"
     misc_feature    complement(order(1059561..1059566,1059573..1059578,
                     1059582..1059584,1059642..1059644,1059666..1059677,
                     1059702..1059704,1059717..1059740,1059936..1059944,
                     1059963..1059965))
                     /locus_tag="Smed_4569"
                     /note="putative active site [active]"
                     /db_xref="CDD:187720"
     misc_feature    complement(order(1059474..1059476,1059666..1059668,
                     1059672..1059674,1059732..1059737,1059939..1059944))
                     /locus_tag="Smed_4569"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187720"
     misc_feature    complement(order(1059561..1059566,1059573..1059578,
                     1059675..1059677,1059702..1059704,1059717..1059725,
                     1059729..1059731,1059738..1059740))
                     /locus_tag="Smed_4569"
                     /note="putative cosubstrate binding site; other site"
                     /db_xref="CDD:187720"
     misc_feature    complement(order(1059561..1059563,1059669..1059671,
                     1059675..1059677))
                     /locus_tag="Smed_4569"
                     /note="catalytic site [active]"
                     /db_xref="CDD:187720"
     misc_feature    complement(1059087..1059371)
                     /locus_tag="Smed_4569"
                     /note="C-terminal subdomain of the formyltransferase
                     domain on ArnA, which modifies lipid A with
                     4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702"
                     /db_xref="CDD:187730"
     misc_feature    complement(order(1059294..1059299,1059309..1059311))
                     /locus_tag="Smed_4569"
                     /note="active site"
                     /db_xref="CDD:187730"
     misc_feature    complement(order(1059090..1059092,1059099..1059110,
                     1059132..1059134))
                     /locus_tag="Smed_4569"
                     /note="hexamer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187730"
     gene            1060445..1061317
                     /locus_tag="Smed_4570"
                     /db_xref="GeneID:5319238"
     CDS             1060445..1061317
                     /locus_tag="Smed_4570"
                     /note="KEGG: sme:SMb21236 putative ATPGTP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ATPGTP-binding protein"
                     /protein_id="YP_001313303.1"
                     /db_xref="GI:150376707"
                     /db_xref="GeneID:5319238"
                     /translation="MDTDRYAMTVSAKEFYSLSSNTIDLVSESAFFARLKMRNGTFKL
                     TQPSRFRELEVAFRPFIAERAASLGQILDVGVSTGLTTVELAKFLEGCGAKVRITATD
                     LFVEAHIVEFAPGVTVFCDPEGWPLQYDLRGLTVRPWIRRLDYVTLAFAPLLLSRFLL
                     QPRLRARIRAGKSRQVQMITRSLPDNGKIRFVENDIMSRSHHLVGRFDLVRAANILNT
                     NYFSLDQIRTAIENIHSYLSGPGALVVVTRTNRALENAGTLFELREDGSFAALERVGG
                     GSEIEKLLLDFRAS"
     gene            1061415..1062353
                     /locus_tag="Smed_4571"
                     /db_xref="GeneID:5319239"
     CDS             1061415..1062353
                     /locus_tag="Smed_4571"
                     /note="C-terminal domain similar to sulfotransferase
                     protein; KEGG: sme:SMb21237 putative enzyme, C-terminal
                     domain similar to sulfotransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313304.1"
                     /db_xref="GI:150376708"
                     /db_xref="GeneID:5319239"
                     /translation="MEGFLMPSQPVRIAYIAGYGRSGSTILDIALGQHASVMGAGEVT
                     SLTRHVWRHNEYCACGNAIRDCSFWSSVFQDWSTSGGSGLMEEYSGLQERFEGLSMLM
                     RLLSGIGLGKQFSLYTLHTKRLLEAMHAHSGRQTIVDSSKLPGRAMAMAQIPGIDMRV
                     IHLVRDGRGVAWSLLKGYERDAKSGLQKEIRPKSVFRTAVRWSMVNLAVEYLSRKLGP
                     EKVMRVRYEDFASDPVAVMQKIGTFLELDLGPVGASLQKGEVMATGHQVAGNRLRMNA
                     SIALNKDEAWRTRMPARQQISFQRLGGWMLRRYGYL"
     misc_feature    <1061889..>1062164
                     /locus_tag="Smed_4571"
                     /note="Sulfotransferase domain; Region: Sulfotransfer_1;
                     pfam00685"
                     /db_xref="CDD:216059"
     gene            1062364..1063977
                     /locus_tag="Smed_4572"
                     /db_xref="GeneID:5318019"
     CDS             1062364..1063977
                     /locus_tag="Smed_4572"
                     /note="KEGG: sme:SMb21239 putative pectate lysase,
                     possibly truncated due to chromosomal point mutation or
                     sequencing artefact protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313305.1"
                     /db_xref="GI:150376709"
                     /db_xref="GeneID:5318019"
                     /translation="MIPLRKLWACLPRQRAVLACLCDGSAFENPVQAVSFGRPSVSAL
                     TRRHERMTAINKSQDVRALGFTIAHCLILGGVLCGSWLAFPAKTAAQTTLAEPLPPKL
                     PDGRQRAFPTAEGFGAGSLGGRGGKVLYVVNTDESGPGSLRACIEASGPRVCVFRTGG
                     TIVLRERSLVVRNPFLTIAGETAPGGGIAIRNGDKQIRPSIEIVTNDVIIRHIRLRPG
                     PHAVRACCSGGLGMYSAAAKDIMLDHISASWGSDETVDSEDASNFTWQWGIASEPLLR
                     GGPGKKNRARNMLFTKGGNISVHHSLFAFGQFRNPLIKMKIPGAVADVVNNVFFSPKW
                     QYVLSFGDEWGHIRANVVGNYKIAGENLQNDHMVHLFDERGGGHAIYVKDNYDEPYRT
                     QPGQDDSLVLAESQRGSVSPQAFNAEAVRASGPEIAYDEVLAHAGATKPQRDAIDRRI
                     VEDVKNRRGRLLANDPNDVGGWPELDAGIPYQDSDMDGISDDWEVANGTDPKNADDAK
                     SDQDGDGWTNLESFLHFMAGDTADAASHE"
     gene            complement(1063988..1065976)
                     /locus_tag="Smed_4573"
                     /db_xref="GeneID:5318020"
     CDS             complement(1063988..1065976)
                     /locus_tag="Smed_4573"
                     /note="PFAM: lipopolysaccharide biosynthesis protein;
                     KEGG: sme:SMb21240 putative MPA1 family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="YP_001313306.1"
                     /db_xref="GI:150376710"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="GeneID:5318020"
                     /translation="MTTFVPDGSLSARAHHRETVDFAAQQGGATVGLFDLWAIVKRRF
                     WFLASIIFVCTLLSAIASFSIPKSYTASSEVVLERKDVRPFATDAALTSIDRDRSAAE
                     TEMDVLQSRKFAGRIVDRLELVNDPTFNPYAPGGDKSSDQGLLRYVQDLIGVRRASTS
                     ARVIPDIKTQRDHAISALLSQFEVSRTGESLAVRLIVTNQNPKLAQQIANTIASLYVE
                     ASLEFKQDERVADKQRALNTGGAVAFLRQSMTQPLLITLRNEEARLLQSRAELAAKYG
                     KNHPQMIDADSQIAGIRSMIEDEVQRILSDLEAESLKPSARIVSTAELPNSPSFPKPG
                     LIIPAALAGSTLLASVLALLLETTDTRVRSGQRTTQLVRIPNLGYVPKVPKHLMSPGA
                     RRSSCIPDWSNVTSAEAERAVYMACRYSDARQLRRVVMTTSCLHDVANASTAWGIATA
                     AAADGRPTAFVNLDFNRHNISYLKNMERSPELIERYLRNRAALTEIVQSIPNLPGFGF
                     IDATHVMTEPFRSLDSDSLCELIMDLKQSGYDFIVLHAPPVLASGDATWLAPFVDGVV
                     LLANWGKTTEEQLLEAAAQLRMNHAHLIGTVINQVNPEIHRRHHYGGFVITSKRIPAG
                     RWHRDRGNGALQERPDAEVNTLTAPSARPSITRPSNVA"
     misc_feature    complement(1065335..1065880)
                     /locus_tag="Smed_4573"
                     /note="Chain length determinant protein; Region: Wzz;
                     pfam02706"
                     /db_xref="CDD:217194"
     misc_feature    complement(1064138..1064863)
                     /locus_tag="Smed_4573"
                     /note="ATPases involved in chromosome partitioning [Cell
                     division and chromosome partitioning]; Region: Mrp;
                     COG0489"
                     /db_xref="CDD:223563"
     gene            complement(1066340..1067623)
                     /locus_tag="Smed_4574"
                     /db_xref="GeneID:5318021"
     CDS             complement(1066340..1067623)
                     /locus_tag="Smed_4574"
                     /note="KEGG: sme:SMb21241 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313307.1"
                     /db_xref="GI:150376711"
                     /db_xref="GeneID:5318021"
                     /translation="MSETGMRTAHQLHFGGQPSRTNLHLAAIERAVVYTAVFLAPYAT
                     LRFSELFFTFSDFFFCLSLFLLLITGRIRSRPLEGATSVWLVAFILLFLGIMLGSLFN
                     GSPQRGLIVMGQYLFAYMILMIILIRDDQREAYRLAGIFLVSVILIDIHGIITFYTVG
                     YVPGEGKGIVTGGKRLATVLRNPNLAAAMNALTLPILLFFWSTGRAKSYLAIPALAII
                     IVTVVLTSSNSGLFSTALCLAVFIALVSTPRLLLRLALGLSIVVGGAALFGSKEMLPK
                     TFQTRVLGALSSGDISEAGTFLSRAALMEEALHIISEEQIKIIGLGADQFRERSVQSA
                     PVHNLYLLLWVEGGLLALIGWLLFSGVGVLLSLAILRVRGDKRALAAVITTILVFLVI
                     ALFNPHMYARYWTMPVLLCFGLGLTQLRGTARGRG"
     gene            complement(1067657..1068898)
                     /locus_tag="Smed_4575"
                     /db_xref="GeneID:5318022"
     CDS             complement(1067657..1068898)
                     /locus_tag="Smed_4575"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21242 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313308.1"
                     /db_xref="GI:150376712"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318022"
                     /translation="MVSSAAVDLRQSEAPGVSVGGHQAVVCFPFIGDLVGGSHMSSLG
                     LIRNLPRDRFVPLVVLHHTDGPVAELFRREGIGFVEAPVLNRLERAAPRNGAAVVNVV
                     RTVPGLVKFLRARNASIVHTNDGRTHLIWGLAARIAGSKHLWHHRGDATSFGLRHVAP
                     WLPNRLVAVSKFASPRPGFFSAAGKCSVVHSPFDVMKMDGFDRVEARNNVLAAIGCSP
                     DTKLLGYVGTLVARKRPILFVEAIAALKRLSPETKVAGLFFGDALNGLDEAARSRAEA
                     LGVADCIHFMGFRYPGEAWIAGLDALLVTAVNEPLGRTLVEAMLLRTPVIAADSGGNP
                     EVVEDGRTGMLVPADDPDEFAKACLALFNNSGLCDHLVETARGEVRSRFSFERHVHAI
                     TSVYENLIGGTGMRRSASAGP"
     misc_feature    complement(1067708..1068796)
                     /locus_tag="Smed_4575"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases and named after YqgM in
                     Bacillus licheniformis about which little is known.
                     Glycosyltransferases catalyze the transfer of sugar
                     moieties from activated donor molecules to...; Region:
                     GT1_YqgM_like; cd03801"
                     /db_xref="CDD:99974"
     misc_feature    complement(1067693..>1068574)
                     /locus_tag="Smed_4575"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     gene            complement(1068953..1069792)
                     /locus_tag="Smed_4576"
                     /db_xref="GeneID:5318023"
     CDS             complement(1068953..1069792)
                     /locus_tag="Smed_4576"
                     /note="PFAM: sulfotransferase;
                     KEGG: sme:SMb21243 putative sulfotransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfotransferase"
                     /protein_id="YP_001313309.1"
                     /db_xref="GI:150376713"
                     /db_xref="InterPro:IPR000863"
                     /db_xref="GeneID:5318023"
                     /translation="MQMRDIDFLIIGATKSATTWLQQSLQQDPGIFMPDPELHYFSRY
                     YDRGDEWYLEHFAAQEHRRLRGEKSNSYMDVPEAAQRIKEKLPQAHLIAQLRNPVDRA
                     YSDYCMLYRRAEVGRDIAQYLDPRQGAGGRFLNGGLYFQQLQAYLDRFPLEQLLVLLY
                     EDLKVDAGAQVARVRGFLKLEADVPLKPLAKKVKDKSEPVVNPTLRRLLRPLKPVAAP
                     FRQNTGFKKLRSLIAGELQYAPLSRDLRERMTDYFALETEKLGALVGRDLTSWLRNRS
                     LEK"
     misc_feature    complement(<1069340..1069780)
                     /locus_tag="Smed_4576"
                     /note="Sulfotransferase domain; Region: Sulfotransfer_1;
                     pfam00685"
                     /db_xref="CDD:216059"
     gene            complement(1070114..1071472)
                     /locus_tag="Smed_4577"
                     /db_xref="GeneID:5318024"
     CDS             complement(1070114..1071472)
                     /locus_tag="Smed_4577"
                     /note="PFAM: polysaccharide biosynthesis protein;
                     KEGG: sme:SMb21244 putative membrane protein, similar to
                     putative polysaccharide transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="YP_001313310.1"
                     /db_xref="GI:150376714"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="GeneID:5318024"
                     /translation="MAFRKKLFKKIGGLRQILSRERTLLERLQSIAHLLTGNILSSVI
                     GLIGFALTARALGPAGYGILALCFSYTRAVERIVSFQSWQPLIKYGAHSLSDNADDFK
                     EMQSLLKFGLLLDVSAALAGWLIAVLFILLASPWLGISEDGASLAILYCTVLPFQVSG
                     MPTAVLRLYGRFMAIAYGQVATSVLRVALCAIGVATGAGLFEFTLIWMSAQIIGTLVL
                     VLFALAELRRQGILSGLLSAPLRGITARFPGLWKFAISANLSLTIRSSANELDTLLVG
                     YLADPTSAGLYHIAKRIGRIAQQAGVQVQAVLYPELARAWAAKALGAFHRAVAQMQAL
                     LLACGLFLIGGLYLLIGPLLSWAAGPEFAAAGPLVIVQSIAVTMTLCGAVIRSALLAM
                     GRENEILRSVTIAAIGFHATAFALIPTMGAMGANVAHIVMASIWLSTMMLSYRRTPAP
                     GP"
     sig_peptide     complement(1071305..1071472)
                     /locus_tag="Smed_4577"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.812) with cleavage site probability 0.800 at
                     residue 56"
     misc_feature    complement(1070126..1071391)
                     /locus_tag="Smed_4577"
                     /note="Membrane protein involved in the export of
                     O-antigen and teichoic acid [General function prediction
                     only]; Region: RfbX; COG2244"
                     /db_xref="CDD:225153"
     misc_feature    complement(1070138..1071373)
                     /locus_tag="Smed_4577"
                     /note="Multidrug and toxic compound extrusion family and
                     similar proteins; Region: MATE_like; cl09326"
                     /db_xref="CDD:245055"
     gene            1071872..1073125
                     /locus_tag="Smed_4578"
                     /db_xref="GeneID:5318025"
     CDS             1071872..1073125
                     /locus_tag="Smed_4578"
                     /note="PFAM: polysaccharide export protein;
                     KEGG: sme:SMb21245 putative OMA family outer membrane
                     protein precursor, similar to ExoF"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="YP_001313311.1"
                     /db_xref="GI:150376715"
                     /db_xref="InterPro:IPR002355"
                     /db_xref="InterPro:IPR003715"
                     /db_xref="GeneID:5318025"
                     /translation="MGISPAVFGTILPRLMNGAFLLLMVLWVLACAMIGAMPARASDY
                     RLNTGDVLTFDFLDDTELPVTATVSGEGEAQFPLIGAVGVVGLTVPEALERLRGEYRK
                     REILVDPKISLDISTFRPIFVLGEVKTPGSFPFYSGLTVEQAVGLAGGMQVVAANASD
                     RIIARARLRGDIEGARAEIVHEAIYAARLVAQLKSSDKIDLADVPEVARDYVTSVPLD
                     GVVELEEKILKADLAANKSQAQILTEGIAQAEGGIDILNQLVLQQKDVVQNSKEDVDR
                     TATLRKRGLNTESDLSRAENNASAEQAQLLETFATLARSRQEMSELKLQLAKLAADRE
                     KDILTQLQAREIAIKKLISQQHSAEEQILLMTAVAEDESKKKQISYTYEIRRNPVGGT
                     PASIKASPLTELVPGDVLTVAIAGM"
     sig_peptide     1071872..1071997
                     /locus_tag="Smed_4578"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.995) with cleavage site probability 0.993 at
                     residue 42"
     misc_feature    1071899..>1072408
                     /locus_tag="Smed_4578"
                     /note="Periplasmic protein involved in polysaccharide
                     export, contains    SLBB domain of b-grasp fold [Cell
                     wall/membrane/envelope biogenesis]; Region: Wza; COG1596"
                     /db_xref="CDD:224512"
     misc_feature    1071974..1072219
                     /locus_tag="Smed_4578"
                     /note="Polysaccharide biosynthesis/export protein; Region:
                     Poly_export; pfam02563"
                     /db_xref="CDD:202285"
     misc_feature    1072232..1072360
                     /locus_tag="Smed_4578"
                     /note="SLBB domain; Region: SLBB; pfam10531"
                     /db_xref="CDD:220798"
     misc_feature    1072376..>1073107
                     /locus_tag="Smed_4578"
                     /note="type I secretion membrane fusion protein, HlyD
                     family; Region: type_I_hlyD; TIGR01843"
                     /db_xref="CDD:130902"
     gene            1073189..1073869
                     /locus_tag="Smed_4579"
                     /db_xref="GeneID:5318026"
     CDS             1073189..1073869
                     /locus_tag="Smed_4579"
                     /note="PFAM: sugar transferase;
                     KEGG: sme:SMb21246 putative glycosyltransferase, possibly
                     periplasmic protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="YP_001313312.1"
                     /db_xref="GI:150376716"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="GeneID:5318026"
                     /translation="MKTFREPAAVSLGLPASLGYYRLKRLLDCLLAGTVFVLCLPLMA
                     ATAVVVWATLGLPLFFSQARAGVEMRVFTVAKFRTMTDARAPDGTLLPDDMRQTASTA
                     LLRRLRFDELPQLIAVLCGHMSMVGPRPLPLATVAGFGELGRMRCRVAPGMTGWAQVN
                     GNTRLSDDEKIALDLWYVAHANLWLDARILLLTVKTLVTGESVHAGHLQEAREFLSRR
                     LGAEPPKA"
     sig_peptide     1073189..1073323
                     /locus_tag="Smed_4579"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.755) with cleavage site probability 0.673 at
                     residue 45"
     misc_feature    1073225..1073800
                     /locus_tag="Smed_4579"
                     /note="Sugar transferases involved in lipopolysaccharide
                     synthesis [Cell envelope biogenesis, outer membrane];
                     Region: WcaJ; COG2148"
                     /db_xref="CDD:225059"
     gene            1073923..1074609
                     /locus_tag="Smed_4580"
                     /db_xref="GeneID:5318027"
     CDS             1073923..1074609
                     /locus_tag="Smed_4580"
                     /note="PFAM: LmbE family protein;
                     KEGG: sme:SMb21247 conserved hypothetical protein,
                     possibly membrane-associated"
                     /codon_start=1
                     /transl_table=11
                     /product="LmbE family protein"
                     /protein_id="YP_001313313.1"
                     /db_xref="GI:150376717"
                     /db_xref="InterPro:IPR003737"
                     /db_xref="GeneID:5318027"
                     /translation="MGSGQVSFGRTLVVAPHPDDEVLGAGGTIARLAAEGEEVFVAVV
                     TEGKPPAFDPEATARIQAEARKAHGVLGVKETIWLRLPAAQLSETSHATVNAALLELV
                     SRLSPQTVLLPFVGDMHMDHQLTFISALVACRPHQAEFPKLVLAYETLSETNWNAPYL
                     SPPFVPNVFVDISDHLEAKLNAMEMFASQVRQPPHERSIATLKALATLRGATVMRKAA
                     EAFVLIRHVV"
     misc_feature    1073923..1074603
                     /locus_tag="Smed_4580"
                     /note="Uncharacterized proteins, LmbE homologs [Function
                     unknown]; Region: COG2120"
                     /db_xref="CDD:225031"
     gene            1074677..1075861
                     /locus_tag="Smed_4581"
                     /db_xref="GeneID:5318028"
     CDS             1074677..1075861
                     /locus_tag="Smed_4581"
                     /note="PFAM: DegT/DnrJ/EryC1/StrS aminotransferase;
                     aromatic amino acid beta-eliminating lyase/threonine
                     aldolase;
                     KEGG: sme:SMb21248 putative aminotransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase"
                     /protein_id="YP_001313314.1"
                     /db_xref="GI:150376718"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="InterPro:IPR001597"
                     /db_xref="GeneID:5318028"
                     /translation="MGRWPVYDEEQIEDVVSILRSGEVNAWTGPHVRNFEAAYERFLG
                     VKHAVALANGTVALDLALFALGLASGDEVIVTPRSFIASASTVPMAGGVAIFADVDPD
                     SQNITAESIRAKLTPKTRGVIVVHLAGWPCDMPAIMALAREKGLWVIEDCAQAHGAEI
                     DGRPVGSFGDIAAFSFCQDKIITTGGEGGLVAMNDEELWKKAWSRKDHGKSYDAVYNR
                     EHPPGFRWLHESIGTNWRMTSIQAVMGSRQLQRLAEWRSIRAHNAAILARAAEEIEAL
                     RTPLPPRGTQHAWYRFYTFLRPERLRPDWTRDRIIAEMNGAGVACFSGSCSEIYLEKA
                     FTDAGMAPPQRLPNARELGETSLAFLVDPAHDTAAMEKAAHVLREVLARASIAMPSRK
                     RG"
     misc_feature    1074686..1075819
                     /locus_tag="Smed_4581"
                     /note="Predicted pyridoxal phosphate-dependent enzyme
                     apparently involved in regulation of cell wall biogenesis
                     [Cell envelope biogenesis, outer membrane]; Region: WecE;
                     COG0399"
                     /db_xref="CDD:223476"
     misc_feature    1074710..1075810
                     /locus_tag="Smed_4581"
                     /note="3-amino-5-hydroxybenzoic acid synthase family
                     (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate
                     (PLP)-dependent aspartate aminotransferase superfamily
                     (fold I). The members of this CD are involved in various
                     biosynthetic pathways for secondary...; Region: AHBA_syn;
                     cd00616"
                     /db_xref="CDD:99740"
     misc_feature    order(1074836..1074841,1075127..1075129,1075136..1075138,
                     1075199..1075201,1075211..1075216,1075649..1075651)
                     /locus_tag="Smed_4581"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99740"
     misc_feature    order(1074836..1074841,1074911..1074913,1075127..1075129,
                     1075136..1075138,1075199..1075201,1075214..1075216)
                     /locus_tag="Smed_4581"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99740"
     misc_feature    1075214..1075216
                     /locus_tag="Smed_4581"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99740"
     gene            complement(1076108..1076950)
                     /locus_tag="Smed_4582"
                     /db_xref="GeneID:5318029"
     CDS             complement(1076108..1076950)
                     /locus_tag="Smed_4582"
                     /note="PFAM: sulfotransferase;
                     KEGG: sme:SMb21249 putative sulfotransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfotransferase"
                     /protein_id="YP_001313315.1"
                     /db_xref="GI:150376719"
                     /db_xref="InterPro:IPR000863"
                     /db_xref="GeneID:5318029"
                     /translation="MASILRRIWRRVEKRVRLTTYAAKSDCFLISYPKSGRTWFRYVL
                     SHYLGAVSGVPEGIDLHNMFSIVPNFDLDPVRGMPGYRFRETKKTIPTILVSHLDYRA
                     SLFLRRPVIMMVRDPRDVIVSAYFHATRHKHRFAGSITEFIKDQDQGMPAMIDYLNRW
                     AAGLSSRPHFVLSYEGLSADTEARTEAVLGFLGCPIDRTALRSAVAAGRFEAMQDRER
                     VEGIPAHDYDRSDVESLRMRRGKAGGFRDYLDEAQVAEVERLCAVDLTAAAKRLVGHT
                     GLNV"
     misc_feature    complement(1076168..1076881)
                     /locus_tag="Smed_4582"
                     /note="Sulfotransferase domain; Region: Sulfotransfer_1;
                     pfam00685"
                     /db_xref="CDD:216059"
     gene            1077445..1078635
                     /locus_tag="Smed_4583"
                     /db_xref="GeneID:5318999"
     CDS             1077445..1078635
                     /locus_tag="Smed_4583"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21250 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313316.1"
                     /db_xref="GI:150376720"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318999"
                     /translation="MSENSNSPAVVAGNMSGARVTIILPSLGAGGTEHVVKLVANHWA
                     QLGCKVTLITLELPHARPYYEFDPRIAIERLGLPPQQGGKIRAGLLVLRRIYRLRSAI
                     RHSQPDFVLSFLTRTNVLTLLATIGLPVPVVVSERNNPALQPFGVFWKWIQRRLYPRA
                     FGLVTMTRGALDYFPEKMRSRGWVIANAVDLPGEWQKRRGNNILTAVGRLTRQKGFDL
                     LIEAFARIASRHPEWKLVIWGEGDDRKSLEALRDALDMTDRVEMPGVTQRPGVWVETA
                     DVFVLSSRYEGWGIVLLEAMAAGLPVVSFACEWGPSDMVEHGEDGLLVPSNDVDALAE
                     ALSRVLADGELRSRLAANAEASAKRYLPDRILSQWDAVALSALKHTARDHAATASVVG
                     AGSA"
     misc_feature    1077496..1078578
                     /locus_tag="Smed_4583"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    1077499..1078557
                     /locus_tag="Smed_4583"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. AmSD in Erwinia amylovora
                     has been shown to be involved in the biosynthesis of
                     amylovoran, the acidic exopolysaccharide acting as a
                     virulence factor. This enzyme may be...; Region:
                     GT1_amsD_like; cd03820"
                     /db_xref="CDD:99990"
     misc_feature    order(1077535..1077537,1078063..1078071,1078249..1078251,
                     1078315..1078317)
                     /locus_tag="Smed_4583"
                     /note="putative ADP-binding pocket [chemical binding];
                     other site"
                     /db_xref="CDD:99990"
     gene            1078743..1080836
                     /locus_tag="Smed_4584"
                     /db_xref="GeneID:5319000"
     CDS             1078743..1080836
                     /locus_tag="Smed_4584"
                     /note="PFAM: MscS Mechanosensitive ion channel;
                     KEGG: sme:SMb21251 conserved hypothetical membrane
                     protein, similar to Y1058"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel MscS"
                     /protein_id="YP_001313317.1"
                     /db_xref="GI:150376721"
                     /db_xref="InterPro:IPR006685"
                     /db_xref="GeneID:5319000"
                     /translation="MGTGVGRVVAGFFLLLIFACATPTMAQEPATTPPGKVQQLMQLL
                     DDPEVRGWIETKKTAPEQAVKPSQGFAANWIAAIRGHLSGLVAAAPRVMPEWRAARER
                     VSGDMQRQGSLPVIWAFAVVLLIGYGAEFLLRYLLRRSANRNNAQGSGGFAAFVRIAP
                     LVAFAVAAVAAFVFADWPRSLEAAVAPLLIAWIVARLLIAIASAVLSPAIGGATAADA
                     ARPHVSLAPHVARYWLRRSVLFICTIAILWAILDMMRALAFPADVRELTSAVLGLIVL
                     GLAVDTAWRRPVSEMAPARSVLRNASIVGFLILLWFFWIAGMEVLFWLGVYVLGLPPL
                     LRFVSAATRTMLDAAAAEDFRVLRNVLIERGARLVIIALAAVWLAMTFRISGAQMMQD
                     DAFNRIFRGVLAGIVILLAADLIWQLAKESINVRIARASLTVEDPGELARNTRLRTLL
                     PILRNFLAAFIAVVAGMMVLSGLGVEVGPLIAGAGVFGVAIGFGSQTLVKDVISGIFY
                     MMDDAFRVGEYIQSGSYKGTVESFSIRSVKLRHHRGPVFTVPFGSLGAVQNMSRDWVI
                     DKFLINVSYDADVAKVKKVVKGVGATLLEDPELAPMIIETVKMKGVEQFGDYGISLSF
                     AMKTKPGHQTQVRRRAQAMIKDAFKNNGIQFASPTVQVAGDDAQSGSAAAAATRDAIA
                     KKNAALAQGGEEAAE"
     sig_peptide     1078743..1078823
                     /locus_tag="Smed_4584"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 27"
     misc_feature    1079880..1080728
                     /locus_tag="Smed_4584"
                     /note="Small-conductance mechanosensitive channel [Cell
                     envelope biogenesis, outer membrane]; Region: MscS;
                     COG0668"
                     /db_xref="CDD:223740"
     misc_feature    1080123..1080707
                     /locus_tag="Smed_4584"
                     /note="Mechanosensitive ion channel; Region: MS_channel;
                     pfam00924"
                     /db_xref="CDD:201506"
     gene            1080932..1082029
                     /locus_tag="Smed_4585"
                     /db_xref="GeneID:5319001"
     CDS             1080932..1082029
                     /locus_tag="Smed_4585"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21252 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313318.1"
                     /db_xref="GI:150376722"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5319001"
                     /translation="MKIAFHAPLKSPDHPVPSGDRQMARMLIEALRLAGHDVGVVSQL
                     RSFLRETSHSAFSAVRDESQREIDRIRRLWRSEGPPDMWFCYHPYYKAPDLIGPSLST
                     EFSIPYVTAESSYSYRRNIGAWKLAQDEVAAGARRAAVNVCFTQRDRHGLDEAIPGAR
                     TALLAPFIDVSPFRDLRRTKQGETRLLAVAMMRAGDKMDSFRMLARSLALVADLPWKL
                     TVIGDGPARAEVLETFAAFPSERLEWLGEKAPQAVPALLAAGDLYIWPGCGEAYGLAY
                     LEAQAAGLPVVAQRTAGVPEVVRDGETGCLTTPGNTEAFAAAVRQLLVDEASRKQMAE
                     RARQFVFEQRSLPAAAARLSGIFAEFVDCAK"
     misc_feature    1080932..1082014
                     /locus_tag="Smed_4585"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    1080935..1081990
                     /locus_tag="Smed_4585"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases and named after YqgM in
                     Bacillus licheniformis about which little is known.
                     Glycosyltransferases catalyze the transfer of sugar
                     moieties from activated donor molecules to...; Region:
                     GT1_YqgM_like; cd03801"
                     /db_xref="CDD:99974"
     gene            1082026..1082796
                     /locus_tag="Smed_4586"
                     /db_xref="GeneID:5319002"
     CDS             1082026..1082796
                     /locus_tag="Smed_4586"
                     /note="PFAM: polysaccharide deacetylase;
                     KEGG: sme:SMb21253 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="YP_001313319.1"
                     /db_xref="GI:150376723"
                     /db_xref="InterPro:IPR002509"
                     /db_xref="GeneID:5319002"
                     /translation="MKMGSAWQRCVDRLDALQDGGKCIDFWLRDDDAVEPSPALDRLL
                     DLTGRFSVPVTLAVIPASTDERLSRSLSSRMHVDVAVHGWSHRNHAPAIEKRQELGAH
                     RPRETVAADLRAGWARLSALYPAALAPLLVPPWNRIDPGLVSELQEIGFEALSVFGPE
                     DGEKCAAFRDTGLQLINTHVDVMDWHGTRGCRPHGDILRDIDRRLDEVENSGGSVGIL
                     THHLVHDESVWEFLSKLFEITTSNPACRWRRITELIDR"
     misc_feature    1082098..1082778
                     /locus_tag="Smed_4586"
                     /note="Putative catalytic domain of uncharacterized
                     bacterial proteins from the carbohydrate esterase 4
                     superfamily; Region: CE4_u4; cd10928"
                     /db_xref="CDD:200554"
     misc_feature    order(1082110..1082121,1082269..1082283,1082419..1082421,
                     1082425..1082427,1082563..1082565,1082677..1082679,
                     1082683..1082685)
                     /locus_tag="Smed_4586"
                     /note="NodB motif; other site"
                     /db_xref="CDD:200554"
     misc_feature    order(1082116..1082121,1082269..1082271,1082281..1082283,
                     1082425..1082433,1082683..1082685)
                     /locus_tag="Smed_4586"
                     /note="putative active site [active]"
                     /db_xref="CDD:200554"
     misc_feature    order(1082116..1082118,1082683..1082685)
                     /locus_tag="Smed_4586"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:200554"
     misc_feature    order(1082119..1082121,1082269..1082271,1082281..1082283)
                     /locus_tag="Smed_4586"
                     /note="putative Zn binding site [ion binding]; other site"
                     /db_xref="CDD:200554"
     gene            complement(1082783..1083613)
                     /locus_tag="Smed_4587"
                     /db_xref="GeneID:5319003"
     CDS             complement(1082783..1083613)
                     /locus_tag="Smed_4587"
                     /note="PFAM: beta-lactamase domain protein;
                     KEGG: sme:SMb21254 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase domain-containing protein"
                     /protein_id="YP_001313320.1"
                     /db_xref="GI:150376724"
                     /db_xref="InterPro:IPR001279"
                     /db_xref="GeneID:5319003"
                     /translation="MQDDTFRVKFWGVRGSLPVSGEQFLHYGGNTPCIEIRCGKEVMI
                     FDAGSGLREAGLSLMSEGVSAFDVFFTHTHYDHIIGLPYFKPIYRCSSAVRFWSGHLH
                     GKMTTAEMINEFMRPPWFPVGTGICQASLDTVDFRPGETLSPRKDVSIRTMSLVHPGG
                     CIGYRVEWGGRAVALIYDTEHEPGILDPVLLDFIAGADLMIYDCTYLESEMSAFRGYG
                     HSTGMHGSLLAKAAGVARLAMFHHDPSRTDAALAAMEQEVQAFFPGAFAACDRQVIDL
                     "
     misc_feature    complement(1082786..1083613)
                     /locus_tag="Smed_4587"
                     /note="Metal-dependent hydrolases of the beta-lactamase
                     superfamily I [General function prediction only]; Region:
                     PhnP; COG1235"
                     /db_xref="CDD:224156"
     gene            1083849..1085048
                     /locus_tag="Smed_4588"
                     /db_xref="GeneID:5319004"
     CDS             1083849..1085048
                     /locus_tag="Smed_4588"
                     /note="KEGG: sme:SMb21255 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313321.1"
                     /db_xref="GI:150376725"
                     /db_xref="GeneID:5319004"
                     /translation="MVQPADREFYANLPLFEAFEGVADEANYRPLPEGWWLAVADIVD
                     STGAIAEGRYKSVNMAGASVISALMNALDEKNLAFVFGGDGALAVVPGGLAAKAKHAL
                     AAAKTWVAEELGLELRAAIVPVSDVRANGFDMRVARFKASEVVSYAMFSGGGASWAEA
                     EMKAGRYQIAAAPTGTRPDLTGLSCRWNPIVSHHGAIVSIIAVPGERGIGPEFQALIG
                     DIVELAEGEERGGHPVPENGPEPHLSVRGITVESRAVAPRGRRSLAWFFVAAQSLALF
                     LCFRLGINFGPFDVKRYARDLASNSDFRKFDDALKMTIDVSLDRLRRIEERLKQGVAA
                     GICRYGLHRQDAALMTCIVPTPMSRDHMHFIDGAAGGYAVAARNLKATLAGSVSQAGS
                     LPSMIKP"
     misc_feature    1083873..1084991
                     /locus_tag="Smed_4588"
                     /note="Protein of unknown function (DUF3095); Region:
                     DUF3095; pfam11294"
                     /db_xref="CDD:221064"
     gene            complement(1085038..1086435)
                     /locus_tag="Smed_4589"
                     /db_xref="GeneID:5319005"
     CDS             complement(1085038..1086435)
                     /locus_tag="Smed_4589"
                     /EC_number="1.1.1.22"
                     /note="PFAM: UDP-glucose/GDP-mannose dehydrogenase;
                     6-phosphogluconate dehydrogenase NAD-binding;
                     3-hydroxyacyl-CoA dehydrogenase NAD-binding;
                     UDP-glucose/GDP-mannose dehydrogenase dimerisation;
                     UDP-glucose/GDP-mannose dehydrogenase;
                     KEGG: sme:SMb21256 putative nucleotide sugar oxidase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="YP_001313322.1"
                     /db_xref="GI:150376726"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR006115"
                     /db_xref="InterPro:IPR006176"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="GeneID:5319005"
                     /translation="MVPAAGPPEPHHRQQNWKPILTSPHHDRLLESISRRTARVGVIG
                     LGYVGLPLAVATARSGFQVTGFDVDPGKIVALDAGRSYIEAVEDEALARESEAGRFRS
                     TTDFSDLGLCDVIIICVPTPLTRHRDPDLSFVENTSRSIAASLRPGQLVVLESTTYPG
                     TTDGIVRLILEETGLKSGADFFIGFSPEREDPGNRSFKTTSIPKVVAGDGPLAAALME
                     RFYAAVVTTVVPVSSNATAEAVKLTENIFRAVNIALVNELKIVYDAMGIDIWEVIEAA
                     KTKPFGYMPFYPGPGLGGHCIPIDPFYLTWKSREYELPTRFIELAGEINSAMPRHVVA
                     RLAEALDKREGKALSRSSVLVVGLAYKKNVPDIRESPSLKLIELIEERGGKAAFYDPH
                     VEEIPATREYMALKGRRSVVFDEATVRSFDAVLIATDHDTVDYTGLAGWSPLIVDTRN
                     VFARRGLAAGHIVKA"
     misc_feature    complement(1085041..1086351)
                     /locus_tag="Smed_4589"
                     /note="UDP-N-acetyl-D-mannosaminuronate dehydrogenase
                     [Cell envelope biogenesis, outer membrane]; Region: WecC;
                     COG0677"
                     /db_xref="CDD:223749"
     misc_feature    complement(<1085977..1086321)
                     /locus_tag="Smed_4589"
                     /note="3-hydroxyacyl-CoA dehydrogenase, NAD binding
                     domain; Region: 3HCDH_N; pfam02737"
                     /db_xref="CDD:202367"
     misc_feature    complement(1085446..1085724)
                     /locus_tag="Smed_4589"
                     /note="UDP-glucose/GDP-mannose dehydrogenase family,
                     central domain; Region: UDPG_MGDP_dh; pfam00984"
                     /db_xref="CDD:201536"
     misc_feature    complement(1085080..1085376)
                     /locus_tag="Smed_4589"
                     /note="UDP-glucose/GDP-mannose dehydrogenase family, UDP
                     binding domain; Region: UDPG_MGDP_dh_C; pfam03720"
                     /db_xref="CDD:217691"
     gene            1086691..1088175
                     /locus_tag="Smed_4590"
                     /db_xref="GeneID:5319006"
     CDS             1086691..1088175
                     /locus_tag="Smed_4590"
                     /note="KEGG: rle:pRL110055 putative adenylate cyclase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenylate/guanylate cyclase"
                     /protein_id="YP_001313323.1"
                     /db_xref="GI:150376727"
                     /db_xref="InterPro:IPR001054"
                     /db_xref="GeneID:5319006"
                     /translation="MTTAGGGGSFLSPTGAGFGFLPRASDRCLAACADGNRCRDDEDY
                     GMSPNNDNVSEILLDKVADWLMRTSLSDETLETIVRGFCERLAAAGLPLMRVHLSFSM
                     LHPLYDALGFTWWRGRGVEVSGLRHEELALNPERFLHSPYYYLLSNNLDHVRRRIDPA
                     LPSEFPIFDELKEQGATDYIAFMQPLGAESEHGMVGSWTTDRQGGFSDDVIAALLRLQ
                     NHLAIAAKVAVLGKLADNMLTTYLGANAGRRVMSGQVRRGDGETVRAVLVMADMRQST
                     MLAEKEGRQAYIESLNGFFDAIATPFNRNGGQILSFVGDGFIGVYPCGRHKEPSEMAS
                     REAFAAVGAATARMAALNAERKTQGRDAIGYGIALHVGNVMFGNVGLRDRLTFSVFGS
                     AVNEVQRLQSLTKKYDHSVVASEAFVNYCGGEWQTLGQEKLRGVRQKFTVLYPRDTAL
                     AAIAQERAYDATEDGLSEAEHVMLLYRNKKRLPAPRGLIDKMLQ"
     misc_feature    1087339..1088067
                     /locus_tag="Smed_4590"
                     /note="Adenylate cyclase, family 3 (some proteins contain
                     HAMP domain) [Signal transduction mechanisms]; Region:
                     CyaA; COG2114"
                     /db_xref="CDD:225025"
     misc_feature    1087480..1088016
                     /locus_tag="Smed_4590"
                     /note="cyclase homology domain; Region: CHD; cd07302"
                     /db_xref="CDD:143636"
     misc_feature    order(1087495..1087497,1087501..1087518,1087621..1087623,
                     1087627..1087635,1087642..1087644,1087852..1087860,
                     1087870..1087875,1087882..1087887,1087990..1087992)
                     /locus_tag="Smed_4590"
                     /note="nucleotidyl binding site; other site"
                     /db_xref="CDD:143636"
     misc_feature    order(1087501..1087503,1087633..1087635)
                     /locus_tag="Smed_4590"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143636"
     misc_feature    order(1087516..1087518,1087552..1087554,1087561..1087566,
                     1087573..1087575,1087585..1087587,1087621..1087626,
                     1087813..1087815,1087822..1087824,1087855..1087866,
                     1087873..1087875,1087990..1087992)
                     /locus_tag="Smed_4590"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143636"
     gene            1088184..1089152
                     /locus_tag="Smed_4591"
                     /db_xref="GeneID:5319007"
     CDS             1088184..1089152
                     /locus_tag="Smed_4591"
                     /note="KEGG: sme:SMb21259 hypothetical exported protein
                     precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313324.1"
                     /db_xref="GI:150376728"
                     /db_xref="GeneID:5319007"
                     /translation="MFRIALLAAALAVPGFTYAQSADETPAYEQKLFDGFEGRDFAPE
                     GGLYYRDNFEQSAGSYEFQSAVKRTGAGGLKLSIVPQCPTDHDGCSERAEIWEKTELR
                     VPYDKGVWYGFSVKLADPVPSDDHRYLIAQWKREIDPGADGDFSPFLALRMDLGKLFA
                     TIETNYLPPVSAGPANVPARCGAGEVPVWGRPELNQMRMLVATDGNWKPEDGSLFNAC
                     TNGVTITNHGNPLPDPKSGWIDFVVFTKPGPDGSGHIELFANGQPIITVKGHIGHADK
                     GLGENQYFKFGPYRAAHTIDWTVYYDDFRRSLRCEDVLTNGNCPFS"
     sig_peptide     1088184..1088243
                     /locus_tag="Smed_4591"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.726 at
                     residue 20"
     misc_feature    1088385..1089101
                     /locus_tag="Smed_4591"
                     /note="Polysaccharide lyase; Region: Polysacc_lyase;
                     pfam14099"
                     /db_xref="CDD:222540"
     gene            1089560..1091449
                     /locus_tag="Smed_4592"
                     /db_xref="GeneID:5319008"
     CDS             1089560..1091449
                     /locus_tag="Smed_4592"
                     /note="PFAM: ABC transporter related;
                     Oligopeptide/dipeptide ABC transporter domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21260 putative mureinpeptideoligopeptide ABC
                     transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313325.1"
                     /db_xref="GI:150376729"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013563"
                     /db_xref="GeneID:5319008"
                     /translation="MTSGADLLRVEGLRITFSVLGGGVEAVRGASFRILPGRVTALVG
                     ESGSGKSAISQAIMGILPSVASVTGRVVFNDPTGNKPVDLLSLDSGGREIQDIRGARI
                     SKIFQEPMTSLSPLHTIGNQISEVLKIHTDIDKAGRRERTEQLLGYVGFSDPKRAYDM
                     YPFELSGGMRQRAMIAMALICSPALLIADEPTTALDVTVQAQILQLLRGLQSKLNMAM
                     LLITHDLGVVANMADEVVVIYHGEIVEAGPVDAIFRNPQHPYLKGLMAAVPHFDMKPG
                     ERLKALREVPVQAGGIIGDRDVRKAGGPNVLVSVRNLSKTFSTRSSGWFGSGSAFRHR
                     AVDNVSFDIRRGECLGLVGESGCGKTTISKILMRAVTPDKGTITFDDGEGALDVLKLD
                     GAELKALRAKIQMVFQDPVSSLSPRMTVKNILSEPLEIHGRGTPKSRVETVRSLLQAV
                     GLDQRFINRYPHSFSGGQRQRIGIARALALVPQLLICDEPVSALDVSVQAQILNLLKD
                     LQKELGLTMLFISHNLAVVDYMADRIAVMYAGRIVELAPREVLMSDPIHPYTKSLLAA
                     VPYPDLDRKLDFDLLQVSGGSDQQRWGVQFADGGDDEALVPADLGGGHFVLARKSVDA
                     RELRP"
     misc_feature    1089578..1091278
                     /locus_tag="Smed_4592"
                     /note="ATPase components of various ABC-type transport
                     systems, contain duplicated ATPase [General function
                     prediction only]; Region: COG1123"
                     /db_xref="CDD:224048"
     misc_feature    1089578..1090300
                     /locus_tag="Smed_4592"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    1089689..1089712
                     /locus_tag="Smed_4592"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    order(1089698..1089703,1089707..1089715,1089878..1089880,
                     1090124..1090129,1090226..1090228)
                     /locus_tag="Smed_4592"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    1089869..1089880
                     /locus_tag="Smed_4592"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    1090052..1090081
                     /locus_tag="Smed_4592"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    1090112..1090129
                     /locus_tag="Smed_4592"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    1090136..1090147
                     /locus_tag="Smed_4592"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    1090214..1090234
                     /locus_tag="Smed_4592"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    1090289..>1090447
                     /locus_tag="Smed_4592"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; pfam08352"
                     /db_xref="CDD:219806"
     misc_feature    1090478..1091197
                     /locus_tag="Smed_4592"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    1090616..1090639
                     /locus_tag="Smed_4592"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    order(1090625..1090630,1090634..1090642,1090781..1090783,
                     1091021..1091026,1091123..1091125)
                     /locus_tag="Smed_4592"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    1090772..1090783
                     /locus_tag="Smed_4592"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    1090949..1090978
                     /locus_tag="Smed_4592"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    1091009..1091026
                     /locus_tag="Smed_4592"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    1091033..1091044
                     /locus_tag="Smed_4592"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    1091111..1091131
                     /locus_tag="Smed_4592"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    1091186..>1091287
                     /locus_tag="Smed_4592"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     gene            1091446..1093347
                     /locus_tag="Smed_4593"
                     /db_xref="GeneID:5319009"
     CDS             1091446..1093347
                     /locus_tag="Smed_4593"
                     /note="PFAM: extracellular solute-binding protein family
                     5;
                     KEGG: sme:SMb21261 putative mureinpeptideoligopeptide ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313326.1"
                     /db_xref="GI:150376730"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="GeneID:5319009"
                     /translation="MITRRTALGLLATAAFPKTLLAAAGGADPLAALVQEGKLPPVGE
                     RLPKTPRVINVAGMGRKAGRHGGTIRSLIGSAKDIRLMTIYGYARLVGYDEELNLQPD
                     VLESYETVEDRIFTFHLREGHRWSDGTPLTAEDFRYCFEDVLLNEDLSPAGLPTSMVM
                     DGQAPKLEIVDERTVRYSWPMPNPVFLQELAAPQPLIVAMPSAYLKQFHKKYQEEDKL
                     KTLLKEQRVKRWSQLHMRMARSYRPENPDLPTLDPWRNTTPLPAEQFVFERNPYYHRV
                     DENGLQLPYIDRFVLSVSSSALIPAKTGTGESDLQANGIDFVDYTYLKDAEKRYPVEV
                     KLWKKTSGSRLALLPNLNCADPVWRALLRDVRVRRALSLAIDRREINMAAFYGLTKES
                     ADTVLPESPLFRPEFASAWIAHDPEQANTLLDAAGLAKRGSDGIRILPDGRKAQIVVE
                     TAGESTLDTDVLQLITDYWREVGISLFIRTSQRDTFRSRAVGGEIIMSIWFGIDNGVP
                     TADMSPHQLAPTADDQLQWPVWGLNYISHGEMGETPDLPAVVELLELLKRWRHSADDA
                     ERADIWRKMLSIYTDQVFSIGLVNSSLQPILVTKKLRNFPEEGLWGFDPTSYFGAYKP
                     DTFWLEQDG"
     sig_peptide     1091446..1091514
                     /locus_tag="Smed_4593"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.953 at
                     residue 23"
     misc_feature    1091584..1093260
                     /locus_tag="Smed_4593"
                     /note="The substrate-binding component of an
                     uncharacterized ABC-type
                     nickel/dipeptide/oligopeptide-like import system contains
                     the type 2 periplasmic binding fold; Region:
                     PBP2_NikA_DppA_OppA_like_4; cd08500"
                     /db_xref="CDD:173865"
     misc_feature    1091737..1093017
                     /locus_tag="Smed_4593"
                     /note="Bacterial extracellular solute-binding proteins,
                     family 5 Middle; Region: SBP_bac_5; pfam00496"
                     /db_xref="CDD:215949"
     gene            1093349..1094347
                     /locus_tag="Smed_4594"
                     /db_xref="GeneID:5318504"
     CDS             1093349..1094347
                     /locus_tag="Smed_4594"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21262 putative mureinpeptideoligopeptide ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313327.1"
                     /db_xref="GI:150376731"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318504"
                     /translation="MLRYILWRIAVMVPTLLIISAFVFAIIELPPGDYFESYIAEIRA
                     QGEGVNMEQIEALRKQYGFDQPPLLRYVHWVAGMLQGDFGYSFEYELPVSDVVGDRLW
                     LTVLVSFVTIIFTWVIAFPIGLYAATHQYSWGDYGLSLVGLIGIAIPNFMLALVLMYF
                     ANIWFGTSIGHLMDQKYLSEPMSWAKAKSILEHIWIPVIIVGAAGTAGMIRRLRANLL
                     DELQKQYVVTARAKGLSPTRTLLKYPLRMALNFFISDIGSILPAIISGAEITAIVLSL
                     ETTGPMLIKALQSQDMYLAGSFLMFLAFLTVIGVLVSDLALAVLDPRIRLQGRSTK"
     misc_feature    1093349..1094332
                     /locus_tag="Smed_4594"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppB; COG0601"
                     /db_xref="CDD:223674"
     sig_peptide     1093349..1093426
                     /locus_tag="Smed_4594"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.831) with cleavage site probability 0.794 at
                     residue 26"
     misc_feature    1093649..1094275
                     /locus_tag="Smed_4594"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1093697..1093702,1093709..1093714,1093727..1093729,
                     1093760..1093771,1093775..1093804,1093811..1093816,
                     1093820..1093822,1093958..1093963,1093967..1093969,
                     1093973..1093975,1093982..1093987,1093991..1093993,
                     1094003..1094008,1094015..1094017,1094066..1094068,
                     1094108..1094113,1094120..1094122,1094141..1094152,
                     1094159..1094164,1094195..1094200,1094228..1094233,
                     1094240..1094245,1094249..1094254,1094261..1094266,
                     1094273..1094275)
                     /locus_tag="Smed_4594"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1093778..1093822,1094141..1094158)
                     /locus_tag="Smed_4594"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1093820..1093822,1093943..1093945,1094159..1094161,
                     1094198..1094200,1094228..1094230)
                     /locus_tag="Smed_4594"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1094018..1094056,1094072..1094077,1094087..1094089)
                     /locus_tag="Smed_4594"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1094344..1095519
                     /locus_tag="Smed_4595"
                     /db_xref="GeneID:5318505"
     CDS             1094344..1095519
                     /locus_tag="Smed_4595"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21263 putative mureinpeptideoligopeptide ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313328.1"
                     /db_xref="GI:150376732"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318505"
                     /translation="MTSPIPAPGEPLPHYVSTAPFDPYSVEVMTEEQVRVNQASQLRL
                     MWWKFKRHKIALASGIFLAALYGMILICEFLAPYDLHTRNVDFIYAPPQSVHFFHEGE
                     FVGPFVYGRTMKLDMDTLKRNYTDDMSDVEPIRFFCRGDGYRFWGLFESNLHLVCPAE
                     GGQLFLLGTDRLGRDVLSRIIYGARISLTIGLLGITVSFVLGIVIGGLAGYHGGVFDL
                     LVQRLIEVLQSIPSIPLWLSLAAIMPATWSPLLIYLGITVILGLLDWTGLARAVRSKL
                     LALREEDYVLAAQLMGAKSGRIIGRHLVPGFMSHLIATATISIPGMILGETALSFLGL
                     GLRPPITSWGILLTEAKSVSVIAFYPWLLFPTIPVILVILAFNFLGDGLRDAADPYK"
     misc_feature    1094461..1094619
                     /locus_tag="Smed_4595"
                     /note="N-terminal TM domain of oligopeptide transport
                     permease C; Region: OppC_N; pfam12911"
                     /db_xref="CDD:221848"
     misc_feature    <1094818..1095516
                     /locus_tag="Smed_4595"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppC; COG1173"
                     /db_xref="CDD:224094"
     misc_feature    1094893..1095420
                     /locus_tag="Smed_4595"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1094941..1094946,1094953..1094958,1094971..1094973,
                     1095001..1095012,1095016..1095045,1095052..1095057,
                     1095061..1095063,1095130..1095135,1095139..1095141,
                     1095145..1095147,1095154..1095159,1095163..1095165,
                     1095175..1095180,1095187..1095189,1095238..1095240,
                     1095280..1095285,1095292..1095294,1095313..1095324,
                     1095331..1095336,1095376..1095381,1095409..1095414)
                     /locus_tag="Smed_4595"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1095019..1095063,1095313..1095330)
                     /locus_tag="Smed_4595"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1095061..1095063,1095115..1095117,1095331..1095333,
                     1095370..1095372,1095379..1095381,1095409..1095411)
                     /locus_tag="Smed_4595"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1095190..1095228,1095244..1095249,1095259..1095261)
                     /locus_tag="Smed_4595"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1095598..1096812
                     /locus_tag="Smed_4596"
                     /db_xref="GeneID:5318506"
     CDS             1095598..1096812
                     /locus_tag="Smed_4596"
                     /note="KEGG: sme:SMb21264 putative membrane-anchored
                     protein, slightly similar to
                     UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)
                     pyrophosphoryl-undecaprenol N-acetylglucosamine
                     transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane-anchored protein"
                     /protein_id="YP_001313329.1"
                     /db_xref="GI:150376733"
                     /db_xref="GeneID:5318506"
                     /translation="MTRRFEDARILMYSHDTFGLGHLRRCRAIAHALVEDYSGLQVLI
                     ISGATIAGAFDYRARVDFVKIPSVIKLRNGEYTSLDRHIELHETLKMRQSIIRSTAET
                     FRPDIFIVDKEPMGLRGEVEDTLAYLKTHGTRLVLGLREIMDAPHLLEEEWNRRDTMR
                     KIEKFYDSVWVYGPPDFYDPLVGLEVPSAVRDRMNFVGFLQRSVPQDAVPGHKPEGDY
                     ILVTTGGGGDGADLIHDVIHAYQEDPELKHNALVVLGPYMPAKQRNKLIKKGSKIPFI
                     KIIEFDNRMEELIAGARGVVSMGGYNTYCEILSFDKPALIVPRLQPREEQLIRAQRAS
                     ALGLIDMLLPQEAEEPLRFAAALKALPQRPPPSLRAKGLRLEGLVHISDIVGEWLDHR
                     SKEHLAVVKRSN"
     misc_feature    1095604..1096797
                     /locus_tag="Smed_4596"
                     /note="Predicted glycosyl transferase [General function
                     prediction only]; Region: COG4671"
                     /db_xref="CDD:227017"
     misc_feature    1096252..1096677
                     /locus_tag="Smed_4596"
                     /note="Glycosyltransferase family 28 C-terminal domain;
                     Region: Glyco_tran_28_C; cl17369"
                     /db_xref="CDD:247923"
     gene            1096819..1098066
                     /locus_tag="Smed_4597"
                     /db_xref="GeneID:5318507"
     CDS             1096819..1098066
                     /locus_tag="Smed_4597"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21265 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313330.1"
                     /db_xref="GI:150376734"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318507"
                     /translation="MSLKPKIAVVLKGYPRLSETFIAQELLGLERAGHELVLIALRRP
                     TDGKRHPVHDEIGAPVHYLPEYLHEEPWRVLRALTKTVTKRSFWRMLRPFFRDLARDR
                     SRNRFRRLGQALVLVAEWPDDAGWLHAHFIHTPASVTSYASMISGIPWTCSAHAKDIW
                     TSQDWELSDKLGRARWTVTCTRSGYEHLRDLSSDKTRVHLSYHGLDLDRFPSFEGEHS
                     RRDGSVPDDPVRIVSVGRAVSKKGYDLLLKALSLLPADLSWRFDHIGAGELTGKLQAL
                     AGELGLEDRLGWHGALDQKEVLSRYREADIFALASRVAANGDRDGLPNVLVEASSQRL
                     ACISTAVSGIPELIDDGHNGMLVPPENPTALAAAIERLIRDPDLRRQLGAAAERRVRA
                     DFDHHSSVGQLIGLFESEWRRSP"
     misc_feature    1096834..1098045
                     /locus_tag="Smed_4597"
                     /note="colanic acid biosynthesis glycosyltransferase WcaL;
                     Provisional; Region: PRK15427"
                     /db_xref="CDD:185325"
     misc_feature    1096834..1098027
                     /locus_tag="Smed_4597"
                     /note="This is a family of GT1 glycosyltransferases found
                     specifically in certain bacteria. amsK in Erwinia
                     amylovora, has been reported to be involved in the
                     biosynthesis of amylovoran, a exopolysaccharide acting as
                     a virulence factor; Region: GT1_amsK_like; cd03799"
                     /db_xref="CDD:99972"
     misc_feature    order(1096915..1096917,1097518..1097526,1097707..1097709,
                     1097791..1097793)
                     /locus_tag="Smed_4597"
                     /note="putative ADP-binding pocket [chemical binding];
                     other site"
                     /db_xref="CDD:99972"
     gene            1098063..1099217
                     /locus_tag="Smed_4598"
                     /db_xref="GeneID:5318508"
     CDS             1098063..1099217
                     /locus_tag="Smed_4598"
                     /note="PFAM: Glycosyltransferase 28 domain;
                     KEGG: sme:SMb21266 putative protein, slightly similar to
                     UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)
                     pyrophosphoryl-undecaprenol N-acetylglucosamine
                     transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 28 protein"
                     /protein_id="YP_001313331.1"
                     /db_xref="GI:150376735"
                     /db_xref="InterPro:IPR007235"
                     /db_xref="GeneID:5318508"
                     /translation="MSSPRVLFYVQHLLGIGHLARASRIAEALIRRDFDVTMVTGGTP
                     VPGFPGDGVKTIALPPVTAGDKGFSGLVDGEGRAVTAAFQEHRRDLLLEIYRRVVPEV
                     VIIEAFPFGRRQMRFELLPLLAEIAASDRPPLVATSLRDILQERLKPGRAEETVEIVK
                     NHFDLVLVHGDPGFARIEETFPLAGEISGKVVYTGLVAPPRPTGVPEKFDVVVSAGGG
                     AVGSALIGAALAAAKLLPNALRWCLVTGPNLPQADFDAFAAAAPPGVSLFRFRRDFGG
                     LLAGARLSISQAGYNTVCDILRAGCACLLVPFTAGGETEQRMRAARLEELDLAGVLPE
                     EGITPELLAAKVGAMLARPKPAIPPLDLDGAAGTARTIEERLPGRRSSKV"
     misc_feature    1098063..1099205
                     /locus_tag="Smed_4598"
                     /note="Predicted glycosyl transferase [General function
                     prediction only]; Region: COG4671"
                     /db_xref="CDD:227017"
     misc_feature    <1098852..1099124
                     /locus_tag="Smed_4598"
                     /note="Glycosyltransferases catalyze the transfer of sugar
                     moieties from activated donor molecules to specific
                     acceptor molecules, forming glycosidic bonds. The acceptor
                     molecule can be a lipid, a protein, a heterocyclic
                     compound, or another carbohydrate...; Region:
                     Glycosyltransferase_GTB_type; cl10013"
                     /db_xref="CDD:245227"
     gene            complement(1099281..1099955)
                     /locus_tag="Smed_4599"
                     /db_xref="GeneID:5318509"
     CDS             complement(1099281..1099955)
                     /locus_tag="Smed_4599"
                     /note="KEGG: mlo:mll3253 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313332.1"
                     /db_xref="GI:150376736"
                     /db_xref="GeneID:5318509"
                     /translation="MMHASHSPHLPEDWRENAYDLARGLAAYSGSRLVAGIGRVIAKH
                     PEAKIANAFNHKQVGCKMWARDTLFATIGASCRRVVVLGGWYGILPAMMLEDPRFDIE
                     IAVSCDIDPAVEPVAQTLNAAFGDRFVAMTADMHALDYRALNADLLINTSCEHITDLR
                     SWLDLLPPGTRVLLQSNDYFSEPTHISCVNSLEEFQAQARLAHVQFAGTLPMKKYRRF
                     MLIGAV"
     gene            1100303..1103014
                     /locus_tag="Smed_4600"
                     /db_xref="GeneID:5318510"
     CDS             1100303..1103014
                     /locus_tag="Smed_4600"
                     /note="PFAM: ABC transporter transmembrane region; ABC
                     transporter related;
                     KEGG: sme:SMb21269 putative ATP-binding component of an
                     ABC transporter with an unusual central domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313333.1"
                     /db_xref="GI:150376737"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="GeneID:5318510"
                     /translation="MEPLLSRYIWTHTRKQQLWILLVVALSMVPYFLSFDLPKQIVNG
                     PIQGAGFDGPEATQPFLAISFDLPFFGEVNLFSGFDLGREGMLLALSLVFLLLVIING
                     LFKFYINTYKGRLGERLLRRIRFELVDRVLRFPPGYLKRVKPAEISTMIKDEVEPMGG
                     FTGDAFVQPALLGGQALTALIFILLQSFWLGIIAAVIVAVQAIIIPRMRRRLLVLGRE
                     RQLTARELSGRVSEIVDGIGTIRAHDTSNYERADIAARLGRIFQIRYDLYQWKFLVKF
                     LNNFLAQVTPFLFYSIGGYFALQGRLDIGQLVAVIGAYKDLPGPLKELIDWDQARQDV
                     QVKYAQVVEQFSVEPLIDPKVQAISVNPAAPLTGALAAVNLSVADDGGSKVVEHISLQ
                     IQPGEAVAITGGTSGGGEALAEAFGRLTWPATGRIVIGDADIHNLPEAVVGRRISYAS
                     SDVFAFQGSLGDNLLYGLKHAPLTEVAYEGDREVHRKWELVEAKLAGNPHYDLNSDWI
                     DYQAAGATGPDDLFTKIRAVLDVVQLSNDVLALAVRSTIDPSEHEAFAGEIVAMRSAL
                     RQRLEAEKLSDLVVFFEPGSYNVEATVGENLLFGTVTDNNRWEMALEEHPFFKTVLKR
                     AGLHETFYGMGLEIAENVVELFRDLPPDHPFFQQLTFMTAEEIPAYEALLQKVRGKSL
                     EEVSEDDAIRIIRLCFGYIEPRHRFGLLTEDLMQKIVEARREFSDGLPADLVGIIEHY
                     QPDRYMASASILDNVLFGRIGHKHTDGSERIRAIVRDLFESLGLHNKVLVFGLDFDVG
                     AGGKRLTSGQRQKLNLARALIRVSDFYIFNQPLLALDQRTQDQITRKAFAFLRDGERK
                     PAILWVLANQDLTELFDRVAHFENGRLVRDEPVETRSTDSDYKELAS"
     misc_feature    <1100684..1101235
                     /locus_tag="Smed_4600"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:216049"
     misc_feature    1100687..>1101730
                     /locus_tag="Smed_4600"
                     /note="ABC-type multidrug transport system, ATPase and
                     permease components [Defense mechanisms]; Region: MdlB;
                     COG1132"
                     /db_xref="CDD:224055"
     misc_feature    1101422..>1101703
                     /locus_tag="Smed_4600"
                     /note="ATP-binding cassette domain of multidrug resistance
                     protein-like transporters; Region: ABCC_MRP_Like; cd03228"
                     /db_xref="CDD:213195"
     misc_feature    1101509..1101532
                     /locus_tag="Smed_4600"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213195"
     misc_feature    order(1101518..1101523,1101527..1101535,1101653..1101655)
                     /locus_tag="Smed_4600"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213195"
     misc_feature    1101644..1101655
                     /locus_tag="Smed_4600"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213195"
     misc_feature    <1102250..1103008
                     /locus_tag="Smed_4600"
                     /note="ABC-type multidrug transport system, ATPase and
                     permease components [Defense mechanisms]; Region: MdlB;
                     COG1132"
                     /db_xref="CDD:224055"
     misc_feature    <1102544..1102948
                     /locus_tag="Smed_4600"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    1102712..1102741
                     /locus_tag="Smed_4600"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    1102772..1102789
                     /locus_tag="Smed_4600"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    1102796..1102807
                     /locus_tag="Smed_4600"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    1102880..1102900
                     /locus_tag="Smed_4600"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            1103111..1103575
                     /locus_tag="Smed_4601"
                     /db_xref="GeneID:5318511"
     CDS             1103111..1103575
                     /locus_tag="Smed_4601"
                     /note="PFAM: cyclic nucleotide-binding;
                     KEGG: sme:SMb21270 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding protein"
                     /protein_id="YP_001313334.1"
                     /db_xref="GI:150376738"
                     /db_xref="InterPro:IPR000595"
                     /db_xref="InterPro:IPR002373"
                     /db_xref="GeneID:5318511"
                     /translation="MLLKDEVEMLRRITLFSGLPPAKLKLLAFTSDRVMYSAGEDLFN
                     QGDIGDAAYVILSGNADVLVSTPNGQLKVAEVEQNSIVGEIAILCNTPRTATVKTTTA
                     LEALRIRKDDFLKLLADFPEMAVEIMRVLADRLSQTTSELTEARSRVQRAEA"
     misc_feature    1103135..>1103554
                     /locus_tag="Smed_4601"
                     /note="cAMP-binding proteins - catabolite gene activator
                     and regulatory subunit of cAMP-dependent protein kinases
                     [Signal transduction mechanisms]; Region: Crp; COG0664"
                     /db_xref="CDD:223736"
     misc_feature    1103153..1103494
                     /locus_tag="Smed_4601"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; Region: CAP_ED;
                     cd00038"
                     /db_xref="CDD:237999"
     misc_feature    order(1103357..1103362,1103387..1103395)
                     /locus_tag="Smed_4601"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:237999"
     misc_feature    order(1103453..1103461,1103471..1103479)
                     /locus_tag="Smed_4601"
                     /note="flexible hinge region; other site"
                     /db_xref="CDD:237999"
     gene            1103744..1104493
                     /locus_tag="Smed_4602"
                     /db_xref="GeneID:5318512"
     CDS             1103744..1104493
                     /locus_tag="Smed_4602"
                     /note="TIGRFAM: methyltransferase FkbM family;
                     KEGG: sme:SMb21271 hypothetical nucleotide-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="FkbM family methyltransferase"
                     /protein_id="YP_001313335.1"
                     /db_xref="GI:150376739"
                     /db_xref="InterPro:IPR006342"
                     /db_xref="GeneID:5318512"
                     /translation="MRAITYFKRTVYFPEKPEKARFFRRLQAGQWEPCTFRNIARFVD
                     ERTTYIDVGGWIGVTPFWAAQTANNVIVVEPDPVCFGILTEMKNGNTGEVALVNAALS
                     QDECLVLHSVGGGFGSSETSALIADDTGMSIEAKTITIPELQAMARTDRLCFKIDIEG
                     YEYKVLDQLRAIDRKKTAGVLLAVHPQILAASLSGPAVLRLIRTAAATFRLIRSLRGF
                     RLENPSALWTAIRKSVSKGELRGFDLLFVAR"
     misc_feature    1103885..1104298
                     /locus_tag="Smed_4602"
                     /note="methyltransferase, FkbM family; Region: fkbM_fam;
                     TIGR01444"
                     /db_xref="CDD:233415"
     gene            complement(1104662..1104920)
                     /locus_tag="Smed_4603"
                     /pseudo
                     /db_xref="GeneID:5318513"
     gene            1105052..1106107
                     /locus_tag="Smed_4604"
                     /db_xref="GeneID:5318514"
     CDS             1105052..1106107
                     /locus_tag="Smed_4604"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     SMART: regulatory protein LacI;
                     KEGG: sme:SMb21272 putative LacI family transcritional
                     regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313336.1"
                     /db_xref="GI:150376740"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318514"
                     /translation="MARSGPKLTRIANTLGVSAATVSNALSGKGRVSAELTDRIRSIA
                     ADLGYVPSQAGRALRTGRSGVIGLVLPDISNPLFPQIAQAIEFAASSAGYGVLIADSR
                     GDIAIQTRAIERLIERGVDGMVIVPRRGTRIADVGCPVAVVDTPSTPGNTVAADHWDG
                     GRQIADHLVGLGHRHLLIIGNNPASNVQNDRVGGLRSALREDVCAETLWIERLEEVNG
                     KGCSLGLAAKVAEGVTAFAAISDLHALRALTELQRAGIHVPEQASVTGFDDLIWSPVV
                     TPALTTIRMDMARIAAIAVEALVRAIGAEEPEHPSVGAPVCAPFSKVPMQLVVRQSTA
                     TPPTTATPPFVTQGEQP"
     sig_peptide     1105052..1105129
                     /locus_tag="Smed_4604"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.700) with cleavage site probability 0.415 at
                     residue 26"
     misc_feature    1105067..1106047
                     /locus_tag="Smed_4604"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    1105082..1105231
                     /locus_tag="Smed_4604"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(1105100..1105114,1105118..1105123,1105130..1105132,
                     1105145..1105150,1105157..1105159,1105196..1105198,
                     1105205..1105207,1105214..1105219,1105223..1105228)
                     /locus_tag="Smed_4604"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    1105196..1105225
                     /locus_tag="Smed_4604"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    1105244..1105987
                     /locus_tag="Smed_4604"
                     /note="Ligand binding domain of the LacI tanscriptional
                     regulator family belonging to the type I
                     periplasmic-binding fold protein superfamily; Region:
                     PBP1_LacI_sugar_binding_like; cd06267"
                     /db_xref="CDD:107262"
     misc_feature    order(1105244..1105246,1105283..1105291,1105298..1105303,
                     1105307..1105312,1105331..1105345,1105349..1105351,
                     1105382..1105384,1105391..1105393,1105400..1105408,
                     1105703..1105705,1105784..1105786,1105796..1105798,
                     1105805..1105810)
                     /locus_tag="Smed_4604"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107262"
     misc_feature    order(1105280..1105285,1105292..1105294,1105427..1105429,
                     1105481..1105483,1105514..1105516,1105622..1105624,
                     1105694..1105696,1105853..1105855,1105904..1105906)
                     /locus_tag="Smed_4604"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107262"
     gene            1106104..1107126
                     /locus_tag="Smed_4605"
                     /db_xref="GeneID:5318372"
     CDS             1106104..1107126
                     /locus_tag="Smed_4605"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb21273 putative spermidineputrescine ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313337.1"
                     /db_xref="GI:150376741"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5318372"
                     /translation="MKNIMLASSALLLIGTTAASAQEKTLTISVYGFAQDAFKELVYD
                     PFEAKCGCNLVVETGNSVERLAKMEANKANPVVDMAVVSMADALSATRSGLIEKIDTS
                     KLSNFDKLYDIAKDPNGDGMSVGYTFYATSIVYRSDKVEITSWADLLGDKLAGHVALP
                     NVTTNQGPPTLYMIGEALGQNTPDLKAAIAAVGEKKDDIVTFYVKSSQLVQLMQQEEI
                     WAAPIGRFSWEGFTKMDLPIKWATPKEGQTGGMNVMVLAKGSKNQDLALQFMDFWLST
                     EIQTALAEKLVDSPANKEVKVSPEIAENLTYGEETVRNLKLIPSAVALDNREAWLSEW
                     NAKVGQ"
     sig_peptide     1106104..1106169
                     /locus_tag="Smed_4605"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.984 at
                     residue 22"
     misc_feature    1106113..1107117
                     /locus_tag="Smed_4605"
                     /note="Spermidine/putrescine-binding periplasmic protein
                     [Amino acid transport and metabolism]; Region: PotD;
                     COG0687"
                     /db_xref="CDD:223759"
     misc_feature    1106116..>1106418
                     /locus_tag="Smed_4605"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; cl17199"
                     /db_xref="CDD:247753"
     misc_feature    1106380..1107015
                     /locus_tag="Smed_4605"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; cl17199"
                     /db_xref="CDD:247753"
     gene            1107162..1108043
                     /locus_tag="Smed_4606"
                     /db_xref="GeneID:5318373"
     CDS             1107162..1108043
                     /locus_tag="Smed_4606"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21274 putative spermidineputrescine ABC
                     transporter permeasee protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313338.1"
                     /db_xref="GI:150376742"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318373"
                     /translation="MRRRVAHPTAAVPRKGLEMFHNRAEALALALPAAVFAAVVFLAP
                     VVILLAEGFHNAEGWSVAAYTGFLSDPLNRTVFLRTLRLGATVTVVAAVIGYAAAFAI
                     VNLPPTAKGRMIGLVVLPLMISPVARTYAWIVILGRTGIVNQALTSVGLTDEPIRFLF
                     TETAVFVGLLQLFLPLMILALISALENMPKDAIPAARVLGANWFQVFWKVILPLTKEG
                     LVIGGTLVFTGSLTAYITPAILGGSKVLMLETLLFQRVTVANDFVSASVIAFILIVMS
                     FAANLLLKRLATARSKR"
     sig_peptide     1107162..1107290
                     /locus_tag="Smed_4606"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.624) with cleavage site probability 0.409 at
                     residue 43"
     misc_feature    <1107651..1107986
                     /locus_tag="Smed_4606"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1107657..1107659,1107873..1107875,1107909..1107911,
                     1107918..1107920,1107948..1107950)
                     /locus_tag="Smed_4606"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1107672..1107677,1107681..1107683,1107687..1107689,
                     1107696..1107701,1107705..1107707,1107717..1107722,
                     1107729..1107731,1107780..1107782,1107822..1107827,
                     1107834..1107836,1107855..1107866,1107873..1107878,
                     1107915..1107920,1107948..1107953,1107960..1107965,
                     1107969..1107974,1107981..1107986)
                     /locus_tag="Smed_4606"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1107732..1107770,1107786..1107791,1107801..1107803)
                     /locus_tag="Smed_4606"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1108040..1108819
                     /locus_tag="Smed_4607"
                     /db_xref="GeneID:5318374"
     CDS             1108040..1108819
                     /locus_tag="Smed_4607"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21275 putative spermidineputrescine ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313339.1"
                     /db_xref="GI:150376743"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR002197"
                     /db_xref="GeneID:5318374"
                     /translation="MNSRLFPVVVLFLVTAFLIGPFFIIVAASVSGGETLAFPPQGLS
                     LKWVAKVFQVESFRESFAMSMLLAIGGTGAALVLGIPASYALSRYRLPFGETIRTVVA
                     LPIIVPGIIVGLALLRYLVVPFRFNITLALFLAHTALVLPYAVRVVSASLNNLRSDIE
                     EAAVLLGSSRAGAFFRVVMPNIRSGILAAFILGFVTSFNQVPVSLFLSGPGIRTLPID
                     MLSYMEITYDPSVAALSALLAFMSIGIVFIAERFLGFSRYV"
     sig_peptide     1108040..1108138
                     /locus_tag="Smed_4607"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.995) with cleavage site probability 0.673 at
                     residue 33"
     misc_feature    1108049..1108810
                     /locus_tag="Smed_4607"
                     /note="ABC-type spermidine/putrescine transport system,
                     permease component II [Amino acid transport and
                     metabolism]; Region: PotC; COG1177"
                     /db_xref="CDD:224098"
     misc_feature    1108220..1108777
                     /locus_tag="Smed_4607"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1108268..1108273,1108280..1108285,1108298..1108300,
                     1108328..1108339,1108343..1108372,1108379..1108384,
                     1108388..1108390,1108451..1108456,1108460..1108462,
                     1108466..1108468,1108475..1108480,1108484..1108486,
                     1108496..1108501,1108508..1108510,1108559..1108561,
                     1108601..1108606,1108613..1108615,1108634..1108645,
                     1108652..1108657,1108694..1108699,1108727..1108732,
                     1108739..1108744,1108748..1108753,1108760..1108765,
                     1108772..1108777)
                     /locus_tag="Smed_4607"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1108346..1108390,1108634..1108651)
                     /locus_tag="Smed_4607"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1108388..1108390,1108436..1108438,1108652..1108654,
                     1108688..1108690,1108697..1108699,1108727..1108729)
                     /locus_tag="Smed_4607"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1108511..1108549,1108565..1108570,1108580..1108582)
                     /locus_tag="Smed_4607"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1108812..1109840
                     /locus_tag="Smed_4608"
                     /db_xref="GeneID:5318375"
     CDS             1108812..1109840
                     /locus_tag="Smed_4608"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21276 putative spermidineputrescine ABC
                     transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313340.1"
                     /db_xref="GI:150376744"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318375"
                     /translation="MSSPAFLSLEKLTLAYGDTVAVKDLDLSIRQGELVAFLGPSGCG
                     KTTTMRSIAGLLKPQSGRISLDGADITRVAANKRSVGLVFQSYALFPHLTVFENVAFG
                     LRLKGLSGTELESRVDAGLKSVGLTSFAARKPAELSGGQQQRVALARSMVMEPKVLLL
                     DEPLSNLDARLRLEMRAELQRVQKETGVTMIFVTHDQGEALSLADRIVVMLNGAIEQI
                     GTPEDIYNRPASAFVADFVGFENIFAIENGRLRAGNGPIALAMPLPHDAAGLAWRPRM
                     VTLGSGPFQGTVRGAAFSGSTREYLLDTPLGALKAEVDAAAPAHSAGTTLAFDLPVEK
                     AAKLERFN"
     misc_feature    1108815..1109831
                     /locus_tag="Smed_4608"
                     /note="ABC-type spermidine/putrescine transport systems,
                     ATPase components [Amino acid transport and metabolism];
                     Region: PotA; COG3842"
                     /db_xref="CDD:226361"
     misc_feature    1108830..1109525
                     /locus_tag="Smed_4608"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    1108926..1108949
                     /locus_tag="Smed_4608"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(1108935..1108940,1108944..1108952,1109064..1109066,
                     1109292..1109297,1109394..1109396)
                     /locus_tag="Smed_4608"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    1109055..1109066
                     /locus_tag="Smed_4608"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    1109220..1109249
                     /locus_tag="Smed_4608"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    1109280..1109297
                     /locus_tag="Smed_4608"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    1109304..1109315
                     /locus_tag="Smed_4608"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    1109382..1109402
                     /locus_tag="Smed_4608"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            1109847..1110770
                     /locus_tag="Smed_4609"
                     /db_xref="GeneID:5318376"
     CDS             1109847..1110770
                     /locus_tag="Smed_4609"
                     /note="PFAM: Inosine/uridine-preferring nucleoside
                     hydrolase;
                     KEGG: sme:SMb21277 putative inosine-uridine preferring
                     nucleoside hydrolase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/uridine-preferring nucleoside hydrolase"
                     /protein_id="YP_001313341.1"
                     /db_xref="GI:150376745"
                     /db_xref="InterPro:IPR001910"
                     /db_xref="GeneID:5318376"
                     /translation="MGIWIDTDMGFDDIAAVLVVLHAAETIDGVSLVFGNVPLQQVKC
                     NAAGAAQAFGWSFPIHQGRALPVLGKLETAERILGQTGLPTAGPGLLEAPPLPESDAF
                     LALCRWLEGGDGPRHILALGPLTNIAALTLARPELAARITDLTWMGGGVSSGNHTASA
                     EFNAFADPEALAIVLAHCLPLRMVDLDLCRKVVAYPDDVEAIRTAGGANATLLADLLA
                     GYISIGTSRGRAGMAIYDPCAAVAMVDGSAISFQSARIDVELAGSLTRGRTVVETRAS
                     HTSFNARFAVDVDAGRARRCLLEALSKEAAK"
     misc_feature    1109853..1110749
                     /locus_tag="Smed_4609"
                     /note="nuc_hydro_IU_UC_XIUA: inosine-uridine preferring,
                     xanthosine-inosine-uridine-adenosine-preferring and,
                     uridine-cytidine preferring nucleoside hydrolases.
                     Nucleoside hydrolases cleave the N-glycosidic bond in
                     nucleosides generating ribose and the...; Region:
                     nuc_hydro_IU_UC_XIUA; cd02651"
                     /db_xref="CDD:239117"
     misc_feature    order(1109868..1109870,1109880..1109885,1109952..1109954,
                     1110075..1110077,1110207..1110209,1110309..1110311,
                     1110327..1110329,1110333..1110335,1110552..1110554)
                     /locus_tag="Smed_4609"
                     /note="active site"
                     /db_xref="CDD:239117"
     misc_feature    order(1110045..1110047,1110240..1110242,1110363..1110365,
                     1110621..1110623,1110627..1110632,1110639..1110641)
                     /locus_tag="Smed_4609"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239117"
     gene            1110767..1112548
                     /locus_tag="Smed_4610"
                     /db_xref="GeneID:5318377"
     CDS             1110767..1112548
                     /locus_tag="Smed_4610"
                     /EC_number="3.5.4.2"
                     /note="PFAM: amidohydrolase;
                     KEGG: sme:SMb21278 probable adenine deaminase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="YP_001313342.1"
                     /db_xref="GI:150376746"
                     /db_xref="InterPro:IPR006680"
                     /db_xref="InterPro:IPR011550"
                     /db_xref="GeneID:5318377"
                     /translation="MNAIQEPNDLNDAGLRARAVAAARGDAGFDVLVAGGTVVDVVTG
                     ECRAADIGIVGAMIASVHAPGSRRDAGTVIEAAGAYLSPGLIDTHMHVESSMVTPAVY
                     ASAVVPRGVTTVVWDPHEFGNVSGIDGVQWAVDATRGLPLRAVVLAPSCVPSAPRLEL
                     AGADFDAAAIAEMLSWPEVGGIAEVMNMRGIIDGDPRMSAIVEAGLKSGKPVNGHARG
                     LVDADLQAFVTAGVSSDHELVSGEDLIAKLRAGLSIELRGSHDHLLPDFVRVLDALGH
                     LPQTVTLCTDDVFPDDLHRDGGLDDVVRRLVRYGLKAEWALQAATLNAARRLGRADLG
                     MIAPGRRADIVLFEDLGDFRALHVLANGRLVASGGTMLQAAAVADVSPLGGTMKIERL
                     KEDDFRIPACGSTARVATVNRPRFTQWGEVTAVVSNGYVVPPEGTTLIAVAHRHGRAD
                     SRPRVGLLEGWGTWLGAFATTVSHDSHNLTVFGGNPRDMMVAANAVIEAGGGMAVVSE
                     GRVEALLPLPLCGLVSDAPLADVAAGFAALREAAGRIVEWQPPYLVFKACFGATLACN
                     AGPHQTDRGIADVGTGRLLESPVLETD"
     misc_feature    1110899..1112533
                     /locus_tag="Smed_4610"
                     /note="Adenine deaminase [Nucleotide transport and
                     metabolism]; Region: AdeC; COG1001"
                     /db_xref="CDD:223933"
     misc_feature    1110905..>1111042
                     /locus_tag="Smed_4610"
                     /note="Superfamily of metallo-dependent hydrolases (also
                     called amidohydrolase superfamily) is a large group of
                     proteins that show conservation in their 3-dimensional
                     fold (TIM barrel) and in details of their active site. The
                     vast majority of the members have a...; Region:
                     metallo-dependent_hydrolases; cl00281"
                     /db_xref="CDD:241750"
     misc_feature    1110989..>1111861
                     /locus_tag="Smed_4610"
                     /note="Adenine deaminase (AdeC) directly deaminates
                     adenine to form hypoxanthine. This reaction is part of one
                     of the adenine salvage pathways, as well as the
                     degradation pathway. It is important for adenine
                     utilization as a purine, as well as a nitrogen source...;
                     Region: AdeC; cd01295"
                     /db_xref="CDD:238620"
     misc_feature    order(1111031..1111033,1111037..1111039,1111409..1111411,
                     1111472..1111474,1111622..1111624)
                     /locus_tag="Smed_4610"
                     /note="active site"
                     /db_xref="CDD:238620"
     misc_feature    1112012..1112518
                     /locus_tag="Smed_4610"
                     /note="Adenine deaminase C-terminal domain; Region:
                     Adenine_deam_C; pfam13382"
                     /db_xref="CDD:222089"
     gene            1112598..1113002
                     /locus_tag="Smed_4611"
                     /db_xref="GeneID:5318378"
     CDS             1112598..1113002
                     /locus_tag="Smed_4611"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313343.1"
                     /db_xref="GI:150376747"
                     /db_xref="GeneID:5318378"
                     /translation="MALAGNCAGVHMRLVPLLLALLIATPAVAVETWPRFMLVDYIHA
                     WSGTSAEHMKSRRTVVDYLSGIRDCLWWQCEYEVTIQQLLHGTNMQIKAARITMDDPA
                     LERVLSQTPFGDMVFLSLRNEPLYGKPAPCSK"
     sig_peptide     1112598..1112687
                     /locus_tag="Smed_4611"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.992) with cleavage site probability 0.990 at
                     residue 30"
     gene            complement(1113102..1114271)
                     /locus_tag="Smed_4612"
                     /db_xref="GeneID:5318379"
     CDS             complement(1113102..1114271)
                     /locus_tag="Smed_4612"
                     /EC_number="3.5.1.32"
                     /note="TIGRFAM: amidohydrolase;
                     PFAM: peptidase M20; peptidase dimerisation domain
                     protein;
                     KEGG: sme:SMb21279 putative amidohydrolase, similar to
                     hippurate hydrolase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="YP_001313344.1"
                     /db_xref="GI:150376748"
                     /db_xref="InterPro:IPR002933"
                     /db_xref="InterPro:IPR010168"
                     /db_xref="InterPro:IPR011650"
                     /db_xref="GeneID:5318379"
                     /translation="MRVPLGIIDDLTFLTALRRDVHAHPELGFEEVRTSDLVAKLLEE
                     AGLRVHRGLGTTGVVGTLQVGNGTRTIGLRADMDALAMPELADRPYKSTVAEKMHACG
                     HDGHTAMLLGAVRHLAATRNFSGTVHFIFQPAEEGRGGARRMVEDGLFELFPCDAVYG
                     LHNMPGLAVNEMAVVPGPQLASSDSWRLTFRGIGTHGAKPHLGRDPITAAGTFLASLQ
                     TIVGRVVDPLQPAVVSACSLQAGDPKALNVIPDTVEIGGTARAYTPHVRDQLEGEIGR
                     LAQGAAAMHGIEADYRFERRIPPVVNDPDATARALSAARSVFGEKTLTSFPPSTAGDD
                     FAFFALEAPGCYVWLGNGPAVDGALHHNSAYDFNDEAIGPGAAFWTALVEQELKA"
     misc_feature    complement(1113105..1114250)
                     /locus_tag="Smed_4612"
                     /note="Metal-dependent
                     amidase/aminoacylase/carboxypeptidase [General function
                     prediction only]; Region: AbgB; COG1473"
                     /db_xref="CDD:224390"
     misc_feature    complement(1113117..1114232)
                     /locus_tag="Smed_4612"
                     /note="M20 Peptidase Aminoacylase 1 subfamily; Region:
                     M20_Acy1_like1; cd05666"
                     /db_xref="CDD:193542"
     misc_feature    complement(order(1113189..1113191,1113786..1113788,
                     1113864..1113866,1113963..1113965,1113969..1113971))
                     /locus_tag="Smed_4612"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:193542"
     misc_feature    complement(order(1113498..1113506,1113522..1113524,
                     1113528..1113533,1113549..1113569,1113618..1113620,
                     1113627..1113629,1113636..1113638,1113648..1113653,
                     1113717..1113719))
                     /locus_tag="Smed_4612"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:193542"
     gene            1114422..1115123
                     /locus_tag="Smed_4613"
                     /db_xref="GeneID:5318380"
     CDS             1114422..1115123
                     /locus_tag="Smed_4613"
                     /note="Involved in nucleotide synthesis and salvage"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase"
                     /protein_id="YP_001313345.1"
                     /db_xref="GI:150376749"
                     /db_xref="InterPro:IPR000836"
                     /db_xref="InterPro:IPR002375"
                     /db_xref="GeneID:5318380"
                     /translation="MTETNRMEPHEFWQELFPPATFSGHGRFRTSFPANLADGRQILL
                     PIRPLSDGKHALASLIVNQASFEVQDALAEELAARLSAFEPEIVAGLPTLGLTLAAAV
                     ARKLGHKRYVPLGTSRKFWYVEDLSVPLSSITTPGQKKRLYADPRMLPLLRNRRVVLI
                     DDVISSGASIVAGLSLMASCGVEPVAIGAAMLQSERWRQPLFDLSAQWPARTVGVFAT
                     PMLVRAEDGTWTAAE"
     misc_feature    <1114860..1114991
                     /locus_tag="Smed_4613"
                     /note="Phosphoribosyl transferase (PRT)-type I domain;
                     Region: PRTases_typeI; cd06223"
                     /db_xref="CDD:206754"
     misc_feature    order(1114902..1114910,1114914..1114928)
                     /locus_tag="Smed_4613"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            complement(1115185..1115652)
                     /locus_tag="Smed_4614"
                     /db_xref="GeneID:5318381"
     CDS             complement(1115185..1115652)
                     /locus_tag="Smed_4614"
                     /note="PFAM: protein of unknown function DUF411;
                     KEGG: ret:RHE_PE00238 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313346.1"
                     /db_xref="GI:150376750"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="InterPro:IPR007332"
                     /db_xref="GeneID:5318381"
                     /translation="MPLSRREFLTALMGFVALTTGTRWAIAGKGHMRIYKDPLCGCCE
                     SWAEAMRRAAYAVEVHNEADMAAIKRRFAVPADLEACHTAVIEGYVIEGHVPPEAIGK
                     LMDERPAIAGLAVPGMPEGSIGMGDSPNASYDVYAFGKSEATPRLFYQVRPRA"
     sig_peptide     complement(1115575..1115652)
                     /locus_tag="Smed_4614"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.835) with cleavage site probability 0.773 at
                     residue 26"
     misc_feature    complement(1115230..1115640)
                     /locus_tag="Smed_4614"
                     /note="Predicted metal-binding protein [General function
                     prediction only]; Region: COG3019"
                     /db_xref="CDD:225564"
     gene            1116012..1117304
                     /locus_tag="Smed_4615"
                     /db_xref="GeneID:5318926"
     CDS             1116012..1117304
                     /locus_tag="Smed_4615"
                     /note="PFAM: Xanthine/uracil/vitamin C permease; sulphate
                     transporter;
                     KEGG: sme:SMb21281 putative integral membrane transporter
                     protein, xanthineuracil permeases family"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/uracil/vitamin C permease"
                     /protein_id="YP_001313347.1"
                     /db_xref="GI:150376751"
                     /db_xref="InterPro:IPR004711"
                     /db_xref="InterPro:IPR006043"
                     /db_xref="InterPro:IPR011547"
                     /db_xref="GeneID:5318926"
                     /translation="MFERLFKLKEHGTTVRTEVIAGVTTFLTMSYIIFVNPDILSTTG
                     MDRNAIFVATCLAAALGSAVMALVANWPIGMAPGMGLNAFFAFTVVAALGFTWQQALG
                     AVFISGIIFLLLTVTGVRSWLIAGIPHSLRSAIATGIGLFLGIIALKNAGIVVDNPAT
                     LVGLGDLKQTGPLLAILGFFVIAVLDALNVRGSILIGILVVTVLSMFLGVSEFQGVLS
                     VPPSIAPTFLQLDIAGALHGGLVHVILVFVLVEVFDATGTLIGVAKRAKLVEEGKPSR
                     LGRALLADSSAIVAGSLMGTSSTTAYVESASGVQAGGRTGLTALTISVLFLAALFISP
                     LAAAVPTYATAPALLYVAGLMMRELTEIEWDDLTEAAPAALTAIAMPFTYSIANGLAF
                     GFVSYVVLKVCTGKWNVIHPATQLVAALFVVRFAFFAE"
     misc_feature    1116012..1117253
                     /locus_tag="Smed_4615"
                     /note="Xanthine/uracil/vitamin C permease [Nucleotide
                     transport and    metabolism]; Region: COG2252"
                     /db_xref="CDD:225161"
     gene            1117555..1117868
                     /locus_tag="Smed_4616"
                     /pseudo
                     /db_xref="GeneID:5318927"
     gene            1117939..1118457
                     /locus_tag="Smed_4617"
                     /db_xref="GeneID:5318928"
     CDS             1117939..1118457
                     /locus_tag="Smed_4617"
                     /note="KEGG: rru:Rru_A1249 kinase-like"
                     /codon_start=1
                     /transl_table=11
                     /product="kinase-like protein"
                     /protein_id="YP_001313348.1"
                     /db_xref="GI:150376752"
                     /db_xref="GeneID:5318928"
                     /translation="MFIIFAGLPGTGKSTIAQTCAGRLGATYLRIDSIEQAIRSSGIL
                     GLQLDVGPAGYMAAYRVAADNLQLGHTVIADSVNPLRITREAFRGIAEKAQAGFLEVE
                     VVCSDKSMHQQRVESRHSTVNGLVLPSWEEVETRHYESWEGPRLELDSARFSVAQCVE
                     RIVEAARLRRPR"
     misc_feature    1117945..>1118292
                     /locus_tag="Smed_4617"
                     /note="Nucleoside/nucleotide kinase (NK) is a protein
                     superfamily consisting of multiple families of enzymes
                     that share structural similarity and are functionally
                     related to the catalysis of the reversible phosphate group
                     transfer from nucleoside triphosphates...; Region: NK;
                     cl17190"
                     /db_xref="CDD:247744"
     misc_feature    order(1117957..1117959,1117972..1117983)
                     /locus_tag="Smed_4617"
                     /note="active site"
                     /db_xref="CDD:238977"
     gene            complement(1118904..1120319)
                     /locus_tag="Smed_4618"
                     /db_xref="GeneID:5318929"
     CDS             complement(1118904..1120319)
                     /locus_tag="Smed_4618"
                     /EC_number="3.5.1.41"
                     /note="PFAM: polysaccharide deacetylase;
                     KEGG: sme:SMb21284 putative enzyme, similar to uricase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="chitin deacetylase"
                     /protein_id="YP_001313349.1"
                     /db_xref="GI:150376753"
                     /db_xref="InterPro:IPR002509"
                     /db_xref="GeneID:5318929"
                     /translation="MRYPRDLLGHGPNPHIAWPDGARIAVQFVINYEEGGENCVLHGD
                     AASEAFLSEIVGAQAWPAQRHWNMESIYEYGARAGFWRLHRLFTERQIAATVYGVATA
                     LKRSPAQVAAMQEAGWEIASHGLKWIEHKDFDAERERAEIAEAIRLHTIVTGKGPTGW
                     YTGRCSVNTLDLVTEAGGFDYVSDSYADDLPYWHEHAGRHQLVIPYTLDANDMRFATP
                     QGFNSGDQFFSYLKDSFDVLYAEGTAGAPKMMSIGLHCRLAGRPGRAAALARFLDYVK
                     GHEKVWVARRIDIARYWAEAYPFRPNENRPSRLSKDDFISRFGGVFEHSDWIARRAFA
                     GELAPANDTASGLHAALCAVFREASEEERLAVLNAHPDLAGKLAQAKRLTESSTSEQA
                     SAGLDALTDEERERFTALNDAYVEKFGFPFIMAVKGRSKDEILAAFETRIGNDGKAEF
                     NTACLQVERIALLRLREMLPE"
     misc_feature    complement(1119423..1120313)
                     /locus_tag="Smed_4618"
                     /note="putative urate catabolism protein; Region:
                     uraD_N-term-dom; TIGR03212"
                     /db_xref="CDD:211797"
     misc_feature    complement(1119444..1120268)
                     /locus_tag="Smed_4618"
                     /note="Catalytic domain of bacterial PuuE allantoinases,
                     Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1),
                     and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977"
                     /db_xref="CDD:200599"
     misc_feature    complement(order(1119555..1119557,1119828..1119836,
                     1119939..1119941,1119951..1119953,1120170..1120172,
                     1120221..1120223,1120227..1120229))
                     /locus_tag="Smed_4618"
                     /note="active site"
                     /db_xref="CDD:200599"
     misc_feature    complement(order(1119555..1119557,1120221..1120223))
                     /locus_tag="Smed_4618"
                     /note="catalytic site [active]"
                     /db_xref="CDD:200599"
     misc_feature    complement(order(1119522..1119524,1119528..1119536,
                     1119597..1119599,1119606..1119611,1119618..1119623,
                     1119630..1119635,1119642..1119644,1119651..1119665,
                     1119675..1119680,1119693..1119698,1119744..1119746,
                     1119753..1119767,1119819..1119827,1119831..1119833,
                     1119924..1119929,1120002..1120007,1120065..1120067,
                     1120074..1120079,1120086..1120094,1120098..1120115,
                     1120119..1120124,1120128..1120133,1120155..1120163,
                     1120194..1120199,1120209..1120211,1120215..1120217))
                     /locus_tag="Smed_4618"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:200599"
     misc_feature    complement(1118907..1119422)
                     /locus_tag="Smed_4618"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3195"
                     /db_xref="CDD:225736"
     gene            1120487..1120858
                     /locus_tag="Smed_4619"
                     /db_xref="GeneID:5318930"
     CDS             1120487..1120858
                     /locus_tag="Smed_4619"
                     /note="TIGRFAM: Hydroxyisourate hydrolase;
                     PFAM: Transthyretin;
                     KEGG: sme:SMb21285 conserved hypothetical protein,
                     transthyretin-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="YP_001313350.1"
                     /db_xref="GI:150376754"
                     /db_xref="InterPro:IPR000895"
                     /db_xref="InterPro:IPR014306"
                     /db_xref="GeneID:5318930"
                     /translation="MQVQDGTSGRLTTHVLDTSSGKPASNLRIDLYRIEGERTELLSS
                     TRTNDDGRCDAPLLNGSTMETGTYELRFHAGEYLGPGAEREVNPFLDVIPIRFGIADR
                     AAHYHVPLLLSPYGYSTYRGS"
     misc_feature    1120511..1120855
                     /locus_tag="Smed_4619"
                     /note="HIUase (5-hydroxyisourate hydrolase) catalyzes the
                     second step in a three-step ureide pathway in which
                     5-hydroxyisourate (HIU), a product of the uricase (urate
                     oxidase) reaction, is hydrolyzed to
                     2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU);
                     Region: TLP_HIUase; cd05822"
                     /db_xref="CDD:100114"
     misc_feature    order(1120526..1120528,1120532..1120534,1120640..1120642,
                     1120805..1120807,1120811..1120813,1120817..1120819,
                     1120844..1120846)
                     /locus_tag="Smed_4619"
                     /note="active site"
                     /db_xref="CDD:100114"
     misc_feature    order(1120538..1120549,1120751..1120756,1120760..1120762,
                     1120772..1120780,1120823..1120825,1120829..1120849)
                     /locus_tag="Smed_4619"
                     /note="homotetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:100114"
     gene            1120864..1122345
                     /locus_tag="Smed_4620"
                     /db_xref="GeneID:5318931"
     CDS             1120864..1122345
                     /locus_tag="Smed_4620"
                     /note="TIGRFAM: Xanthine dehydrogenase small subunit;
                     PFAM: ferredoxin; molybdopterin dehydrogenase FAD-binding;
                     [2Fe-2S]-binding domain protein; CO dehydrogenase
                     flavoprotein domain protein;
                     KEGG: sme:SMb21286 probable xanthine dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase small subunit"
                     /protein_id="YP_001313351.1"
                     /db_xref="GI:150376755"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR002346"
                     /db_xref="InterPro:IPR002888"
                     /db_xref="InterPro:IPR005107"
                     /db_xref="InterPro:IPR006058"
                     /db_xref="InterPro:IPR014307"
                     /db_xref="GeneID:5318931"
                     /translation="MTIEFRNTIRFLLNDRSVELADVSPVQTLLDFLRIDRNLRGTKE
                     GCAEGDCGACTVLVGRLLDGKLRYESVNACIRFVASLDGCHVVTVEALAQPNGPLHPV
                     QQAMVDTHASQCGFCTPGFVMSLYGLWMANAKPSIQQIEKALQGNLCRCTGYAAIIRA
                     AEAIASVGELGKDPLIVEREQITRQLKALQDGRRVEIGGEDERVVLPASLDDFAAVLQ
                     ANPKATIVAGSTDVGLWVTKFMRNIAPVVHLSHLEELRRISVGVDGITLAAGVSYTEA
                     YPAIVRHFPQLRELWDRIGGEQVRNMGTVGGNIANGSPIGDTPPALIALGASVTLRKG
                     TNRRTLPLEAFFLEYGKQDRESGEFVESVRIPFLDETHRFAVYKISKRFDEDISAVCG
                     AFRVKLDGDGRVADVAIAFGGMAGTPKRARNVEAALKGAQWNDAAVEAGVAAFERDFA
                     PLTDWRASSEYRMLVARNLLRRFHLETQETRHVRIDRTVAVAM"
     misc_feature    1120864..1122336
                     /locus_tag="Smed_4620"
                     /note="Xanthine dehydrogenase, iron-sulfur cluster and
                     FAD-binding subunit A [Nucleotide transport and
                     metabolism]; Region: XdhA; COG4630"
                     /db_xref="CDD:226977"
     misc_feature    1120888..1121103
                     /locus_tag="Smed_4620"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    order(1120987..1120992,1120999..1121001,1121008..1121010,
                     1121014..1121025,1121080..1121085)
                     /locus_tag="Smed_4620"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    order(1120999..1121001,1121014..1121016,1121023..1121025,
                     1121083..1121085)
                     /locus_tag="Smed_4620"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     misc_feature    1121125..1121325
                     /locus_tag="Smed_4620"
                     /note="[2Fe-2S] binding domain; Region: Fer2_2; pfam01799"
                     /db_xref="CDD:201981"
     misc_feature    1121986..1122294
                     /locus_tag="Smed_4620"
                     /note="CO dehydrogenase flavoprotein C-terminal domain;
                     Region: CO_deh_flav_C; pfam03450"
                     /db_xref="CDD:217566"
     gene            1122359..1124692
                     /locus_tag="Smed_4621"
                     /db_xref="GeneID:5318932"
     CDS             1122359..1124692
                     /locus_tag="Smed_4621"
                     /EC_number="1.17.1.4"
                     /note="TIGRFAM: Xanthine dehydrogenase molybdopterin
                     binding subunit;
                     PFAM: aldehyde oxidase and xanthine dehydrogenase a/b
                     hammerhead; aldehyde oxidase and xanthine dehydrogenase
                     molybdopterin binding;
                     KEGG: sme:SMb21287 putative xanthine dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdopterin binding
                     subunit"
                     /protein_id="YP_001313352.1"
                     /db_xref="GI:150376756"
                     /db_xref="InterPro:IPR000674"
                     /db_xref="InterPro:IPR008274"
                     /db_xref="InterPro:IPR014309"
                     /db_xref="GeneID:5318932"
                     /translation="MNVMQPVVRVRGAVHDKERHESGHKHVSGTAEYIDDIPEPAGTL
                     HGYLGLSQRAHAEILSVNFEAVHDSPGVVGVLTAQDIPGENDISPAHKHDDPVFATGR
                     VEFHGQPIFAVIATSREAARRAAAKVKIDYRDLPHVTDVLEAAAANYPLVIDPLKLER
                     GDIDAGFAKAKNIVSGEMRIGGQDHFYLEGQISFAIPGEDDEVTVFSSTQHPSETQLM
                     VAHVLGVPSNAVTVNVRRMGGGFGGKETQANLFAAVAAVAARKYRRAVKVRPDRDDDM
                     AATGKRHDFHVDYKIGFDDDGRIEAVDAVFAARCGFSADLSGPVTDRALFHADNCYFY
                     PNVRLRSRPLKTNTVSNTAFRGFGGPQGMVGGERMIEDVAYALGKDPLEIRKLNFYGG
                     EGRNLTPYHQTVEDNIIGRIIEELETSSDYAARRKAIIAFNRENHVIKRGIALTPVKF
                     GISFTKTEYNQAGALIHVYTDGSIQLNHGGTEMGQGLYTKVAQVVADEFQVDLDHIKV
                     TATSTGKVPNTSATAASSGSDLNGMAAANACQQIKERLVRFAAERYGVSQADVAFEPN
                     TVRIGAERIPFADLIKAAYAARVQLSAAGFYKTPKIHWSRAEGRGRPFYYFAYGASCS
                     EVSVDTLTGEYQVERTDIIHDVGKSLNPALDLGQVEGAFVQGMGWLTTEELWWDAKGR
                     LRTHAPSTYKIPLASDRPRVFNVHLADWSVNREETIRRSKAVGEPPFMLGISVLEAIS
                     MAAASVADYRIPPRIDAPATPERVLMAVERLRAARAG"
     misc_feature    1122359..1124689
                     /locus_tag="Smed_4621"
                     /note="Xanthine dehydrogenase, molybdopterin-binding
                     subunit B [Nucleotide transport and metabolism]; Region:
                     XdhB; COG4631"
                     /db_xref="CDD:226978"
     misc_feature    1122440..1122766
                     /locus_tag="Smed_4621"
                     /note="Aldehyde oxidase and xanthine dehydrogenase, a/b
                     hammerhead domain; Region: Ald_Xan_dh_C; smart01008"
                     /db_xref="CDD:214971"
     misc_feature    1122833..1124458
                     /locus_tag="Smed_4621"
                     /note="Molybdopterin-binding domain of aldehyde
                     dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738"
                     /db_xref="CDD:217210"
     gene            1124728..1125585
                     /locus_tag="Smed_4622"
                     /db_xref="GeneID:5318933"
     CDS             1124728..1125585
                     /locus_tag="Smed_4622"
                     /note="TIGRFAM: Xanthine dehydrogenase accessory protein
                     XdhC;
                     PFAM: protein of unknown function DUF182;
                     KEGG: sme:SMb21288 probable xanthine dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory protein XdhC"
                     /protein_id="YP_001313353.1"
                     /db_xref="GI:150376757"
                     /db_xref="InterPro:IPR003777"
                     /db_xref="InterPro:IPR014308"
                     /db_xref="GeneID:5318933"
                     /translation="MTGRKDIRDFLSREPACVLVQVASAAGSTPRDTDAWMLVSKDRT
                     FATIGGGQLEFMAIDHARKLLHGANGDLRLAIPLGPEIGQCCGGRVTLSFKRLDAVMR
                     AAIIESSDNEIARRPHVYIFGAGHVGNALARALSHVPLRTVLVDTREHELSAADAPDV
                     ETCLTAMPEAVVRDAPPGSAFVVLTHDHALDFLITTEALGREDASYVGMIGSKTKRAT
                     FKNWLSREVNRPELFERLVCPIGGTAVKDKRPEVIAALAAAEVVTAALNRHLQPRAPS
                     PKSQRSVKA"
     misc_feature    1124749..1124928
                     /locus_tag="Smed_4622"
                     /note="XdhC and CoxI family; Region: XdhC_CoxI; pfam02625"
                     /db_xref="CDD:202317"
     misc_feature    1124779..1125486
                     /locus_tag="Smed_4622"
                     /note="xanthine dehydrogenase accessory protein XdhC;
                     Region: xanthine_xdhC; TIGR02964"
                     /db_xref="CDD:234073"
     misc_feature    1125082..1125486
                     /locus_tag="Smed_4622"
                     /note="XdhC Rossmann domain; Region: XdhC_C; pfam13478"
                     /db_xref="CDD:222162"
     gene            complement(1125670..1126617)
                     /locus_tag="Smed_4623"
                     /db_xref="GeneID:5318934"
     CDS             complement(1125670..1126617)
                     /locus_tag="Smed_4623"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb21291 putative transcriptional regulator,
                     LysR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001313354.1"
                     /db_xref="GI:150376758"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318934"
                     /translation="MSYLDNVRVFVRVVELGTLSAAGRDQRVTPAVASNRIKELERHM
                     GVRLFNRTTRKLTPTEHGRVFYEGAVKILEAVNEAESAIADLSRNPKGALKITAPLGI
                     GRRLIAPGIPEFHDRYPDIEVRLRLSDHNVDILAEGVDIAFKLGILEDSNLRMRGIMN
                     CDRVLCGSPRYFERRGTPSSPDDLLSQSHDCLLLRYPGSKEYYWTLQTPDGVRKFEVA
                     GPYDSDDGDVLTQWALDGRGIVNKPLFEVKHYIDEGLLVPILEETPPLGAQLAAIYPH
                     KRFQDPKVRLMIDFMAERCQRLIGKMLAEPAEVPERSSA"
     misc_feature    complement(1125724..1126608)
                     /locus_tag="Smed_4623"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    complement(1126429..1126608)
                     /locus_tag="Smed_4623"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    complement(1125745..1126344)
                     /locus_tag="Smed_4623"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator CrgA and its related
                     homologs, contains the type 2 periplasmic binding domain;
                     Region: PBP2_CrgA_like; cd08422"
                     /db_xref="CDD:176114"
     misc_feature    complement(order(1125808..1125810,1125889..1125891,
                     1125940..1125942,1126135..1126137,1126141..1126143,
                     1126183..1126185,1126300..1126302,1126312..1126314))
                     /locus_tag="Smed_4623"
                     /note="putative effector binding pocket; other site"
                     /db_xref="CDD:176114"
     misc_feature    complement(order(1125913..1125915,1125922..1125927,
                     1125946..1125960,1126048..1126050,1126237..1126257,
                     1126261..1126263,1126273..1126275,1126282..1126287,
                     1126291..1126296,1126306..1126311))
                     /locus_tag="Smed_4623"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176114"
     gene            1126767..1128005
                     /locus_tag="Smed_4624"
                     /db_xref="GeneID:5318935"
     CDS             1126767..1128005
                     /locus_tag="Smed_4624"
                     /note="PFAM: protein of unknown function DUF989;
                     KEGG: sme:SMb21292 conserved hypothetical membrane
                     protein, paralogue of Y20848"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313355.1"
                     /db_xref="GI:150376759"
                     /db_xref="InterPro:IPR009056"
                     /db_xref="InterPro:IPR010389"
                     /db_xref="GeneID:5318935"
                     /translation="MYEYAIAWDWLTFAVRWLHVITGIAWIGSSFYFVALDLGLKQRP
                     GLPVGAYGEEWQVHGGGFYHIQKYLVAPANMPEHLIWFKWESYVTWLSGFGMLALVYY
                     AGADLYLIDPNVLDVSKPMAIAISLASLGFGWLAYDMICRSPFGNDNTRLMVLLYFIL
                     VAVAWGYTQLFTGRAAYLHLGAFTATIMSANVFFIIIPNQKKVVADLIAGRTPDPALG
                     KQAKQRSTHNNYLTLPVLFLMLSNHYPLAFGTQYNWIIASLVFLMGVTIRHWFNTRHA
                     NKGSPTWTWLATVLLFIAIMWLSTVPKVLSEGGEARAATAAEAVVASPDFSKVRDTVL
                     GRCSMCHAREPGWEGIIVPPKGVILESDGDIVAHAREIYLQAGRSHAMPPANVTGITE
                     EERQLIASWYERTIKEGKVQ"
     misc_feature    1126773..1127993
                     /locus_tag="Smed_4624"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG3748"
                     /db_xref="CDD:226271"
     misc_feature    1126779..1127669
                     /locus_tag="Smed_4624"
                     /note="Protein of unknown function (DUF989); Region:
                     DUF989; pfam06181"
                     /db_xref="CDD:218928"
     misc_feature    1127748..1127972
                     /locus_tag="Smed_4624"
                     /note="Cytochrome c; Region: Cytochrom_C; pfam00034"
                     /db_xref="CDD:215669"
     gene            1128002..1129345
                     /locus_tag="Smed_4625"
                     /db_xref="GeneID:5318936"
     CDS             1128002..1129345
                     /locus_tag="Smed_4625"
                     /note="Catalyzes the deamination of guanine"
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="YP_001313356.1"
                     /db_xref="GI:150376760"
                     /db_xref="InterPro:IPR006680"
                     /db_xref="InterPro:IPR011550"
                     /db_xref="InterPro:IPR013108"
                     /db_xref="InterPro:IPR013838"
                     /db_xref="InterPro:IPR014311"
                     /db_xref="GeneID:5318936"
                     /translation="MRDLLIRGRVLTFLKEPQGIDDTASYRFIEDGAVFVRSGKIVHI
                     GPYVDVAKQAGPDTEVADHRPHLVLPGLIDTHLHFPQTQAIASYGAQLLEWLNTYIFV
                     EEQKFKAPEHAAFIAGRFMDELLSNGTTTAAAYCSVHPESVDAFFAAAEERDMLMIGG
                     KVMMDRNAPDALQDTSQKGYDETKALIARWHGRGRAHYAITPRFAITSTPEQMEMSRA
                     LAAEHPDCYVQTHLSENRDEITFATSLYPEAKDYTDIYARYELLGRKTLLGHCIHLSD
                     REISALAETEAVGVFCPTSNLFLGSGLFDRDRFDKLGARHAVATDVGAGTSFSMLETM
                     DEAYKVLHLQGQRLSPLNSFYMMTLGNARALDLEDRIGSLHAGADADIVVLDSRAKPA
                     MELRMQVASSLAEELFIVQTMGDDRSVAEVYVAGKPMKCRRRQTKAQADVELATA"
     misc_feature    1128002..1129300
                     /locus_tag="Smed_4625"
                     /note="guanine deaminase; Provisional; Region: PRK09228"
                     /db_xref="CDD:236419"
     misc_feature    1128017..1129279
                     /locus_tag="Smed_4625"
                     /note="Guanine deaminase (GDEase). Guanine deaminase is an
                     aminohydrolase responsible for the conversion of guanine
                     to xanthine and ammonia, the first step to utilize guanine
                     as a nitrogen source. This reaction also removes the
                     guanine base from the pool and...; Region: GDEase;
                     cd01303"
                     /db_xref="CDD:238628"
     misc_feature    order(1128227..1128229,1128233..1128235,1128692..1128694,
                     1128701..1128703,1128809..1128811,1128962..1128964)
                     /locus_tag="Smed_4625"
                     /note="active site"
                     /db_xref="CDD:238628"
     gene            complement(1129627..1130106)
                     /locus_tag="Smed_4626"
                     /db_xref="GeneID:5319261"
     CDS             complement(1129627..1130106)
                     /locus_tag="Smed_4626"
                     /note="PFAM: heat shock protein Hsp20;
                     KEGG: sme:SMb21295 putative small heat shock protein,
                     HSP20 family"
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein Hsp20"
                     /protein_id="YP_001313357.1"
                     /db_xref="GI:150376761"
                     /db_xref="InterPro:IPR002068"
                     /db_xref="GeneID:5319261"
                     /translation="MRTSFDFSPLSRSSVGFEHLFDLLDSASRLAPGDNWPPYDILRV
                     GENQYRIAMSVAGFAPDEITITHEQQMLTITGAKAGEDDTEYLYRGIAARSFERRFQL
                     ADFVTVTGANLANGMLKIDLVRELPEQMKPRRIEIQQAEALPGGESSKQIEGEKHAA"
     misc_feature    complement(1129693..1130106)
                     /locus_tag="Smed_4626"
                     /note="Molecular chaperone (small heat shock protein)
                     [Posttranslational modification, protein turnover,
                     chaperones]; Region: IbpA; COG0071"
                     /db_xref="CDD:223149"
     misc_feature    complement(1129735..1129998)
                     /locus_tag="Smed_4626"
                     /note="Alpha-crystallin domain (ACD) found in Escherichia
                     coli inclusion body-associated proteins IbpA and IbpB, and
                     similar proteins.  IbpA and IbpB are 16 kDa small heat
                     shock proteins (sHsps). sHsps are molecular chaperones
                     that suppress protein aggregation...; Region:
                     ACD_IbpA-B_like; cd06470"
                     /db_xref="CDD:107227"
     misc_feature    complement(order(1129756..1129761,1129813..1129815,
                     1129936..1129941,1129945..1129947,1129951..1129953,
                     1129978..1129992))
                     /locus_tag="Smed_4626"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:107227"
     gene            1130430..1130735
                     /locus_tag="Smed_4627"
                     /db_xref="GeneID:5319262"
     CDS             1130430..1130735
                     /locus_tag="Smed_4627"
                     /note="PFAM: protein of unknown function DUF982;
                     KEGG: sme:SMb21296 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313358.1"
                     /db_xref="GI:150376762"
                     /db_xref="InterPro:IPR010385"
                     /db_xref="GeneID:5319262"
                     /translation="MLLNEIPWTIPLTVRLSNGLTHSFASVYEALDFLENEWPLRRGE
                     RYERAVRTCRRALNRMTPAAVAREAFIAACLEAGMPLVMTPPAQKPQTGIVKAAQSA"
     misc_feature    1130460..1130675
                     /locus_tag="Smed_4627"
                     /note="Protein of unknown function (DUF982); Region:
                     DUF982; pfam06169"
                     /db_xref="CDD:218923"
     gene            complement(1130756..1132810)
                     /locus_tag="Smed_4628"
                     /db_xref="GeneID:5319263"
     CDS             complement(1130756..1132810)
                     /locus_tag="Smed_4628"
                     /note="TIGRFAM: penicillin-binding protein 1C;
                     PFAM: glycosyl transferase family 51; penicillin-binding
                     protein transpeptidase; Penicillin-binding domain protein;
                     KEGG: sme:SMb21297 probable bifunctional
                     penicillin-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1C"
                     /protein_id="YP_001313359.1"
                     /db_xref="GI:150376763"
                     /db_xref="InterPro:IPR001264"
                     /db_xref="InterPro:IPR001460"
                     /db_xref="InterPro:IPR009647"
                     /db_xref="InterPro:IPR011815"
                     /db_xref="GeneID:5319263"
                     /translation="MPIALAVSALAAIALLWADRAFPPPLSEAATVSAEVLDRDGHLL
                     RAFATEGGLWRLKTTVEDVDPRFIEMLIAYEDQRFREHRGVDPLALGRAALQFLTNGR
                     IVSGASTLSMQVARLIEPRERRTLAAKFLQVARAIQIERRLDKDEILDLYLTRAPYGG
                     NLEGVRAASLAWFGKEPRRLSAGEAALMVALPQLPEKRRPDRNLAAAEAARKRVLARA
                     AVAKVIGDGEAERAAMTAIPTRRLQLPVHAAHLAEAARRKDPAALEHPTTLSRNVQRG
                     LETVARESAVKLGSKVSIAMVMADIRTGEIVGEVGSANYFDASRSGWIDMTRITRSPG
                     STLKPFIYGLAFEEGLVSQETIVEDRPADFFGYRPRNFDMSYQGDVSVRQALQLSLNV
                     PAIRLLDAVGPSRLMVRFRRADIRPRLPPHEAPGLAIGLGGVGITLRELVQLYAGLAN
                     HGIPVRLGNGVEGVPGPIDGEPLLSTVAAWHVADILSDVLPPAGSRRRGIAYKTGTSY
                     GYRDAWSVGFDGRYVLGVWAGRPDNGAVPGLTGYGAAAPILFEGFVKAGIGTTPLPGP
                     PAGAVRLAQADLPVSQRRFSINANGLLAASAREPAPQIVFPPEGAHVELSVRGQAAMS
                     PLTLKLQGGRAPFRWLANGRPLPEATRRRVSRWLPDGGGYSTLTVIDALGRAASVRVF
                     VQ"
     sig_peptide     complement(1132754..1132810)
                     /locus_tag="Smed_4628"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.952) with cleavage site probability 0.451 at
                     residue 19"
     misc_feature    complement(1130759..1132747)
                     /locus_tag="Smed_4628"
                     /note="Membrane carboxypeptidase/penicillin-binding
                     protein PbpC [Cell envelope biogenesis, outer membrane];
                     Region: PbpC; COG4953"
                     /db_xref="CDD:227289"
     misc_feature    complement(1132202..1132693)
                     /locus_tag="Smed_4628"
                     /note="Transglycosylase; Region: Transgly; pfam00912"
                     /db_xref="CDD:201501"
     misc_feature    complement(1131164..1131922)
                     /locus_tag="Smed_4628"
                     /note="Penicillin binding protein transpeptidase domain;
                     Region: Transpeptidase; cl17760"
                     /db_xref="CDD:248314"
     misc_feature    complement(1130768..1131040)
                     /locus_tag="Smed_4628"
                     /note="Penicillin-Binding Protein C-terminus Family;
                     Region: BiPBP_C; pfam06832"
                     /db_xref="CDD:219195"
     gene            complement(1132894..1138339)
                     /locus_tag="Smed_4629"
                     /pseudo
                     /db_xref="GeneID:5319264"
     gene            1138567..1139322
                     /locus_tag="Smed_4630"
                     /db_xref="GeneID:5319265"
     CDS             1138567..1139322
                     /locus_tag="Smed_4630"
                     /note="PFAM: regulatory protein DeoR; regulatory protein
                     DeoR;
                     KEGG: sme:SMb21299 putative transcriptional regulator,
                     DeoR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="YP_001313360.1"
                     /db_xref="GI:150376764"
                     /db_xref="InterPro:IPR001034"
                     /db_xref="InterPro:IPR014036"
                     /db_xref="GeneID:5319265"
                     /translation="MNMASRRASRIAILSNALSSRRTVHLKEAAALLGVSEMTVRRDV
                     ADNPGLFGYLGGHIVSAADIESDAPYELARAADSHAAAKREACRHAARHIRPDETIFI
                     DCGTTLEYLVDLIPENYSITAVCYSLNTAERLTRKANLRIVMLGGVYHSSSASFSGAP
                     GLETLERLGINVAFLSAAGIDPVRGATCVHFHEVPVKQKVISLARENYLVADKSKLGK
                     LKAAFFAPLSAFRSLVTEDGETALAGDSALTGT"
     misc_feature    1138573..1139274
                     /locus_tag="Smed_4630"
                     /note="DNA-binding transcriptional repressor DeoR;
                     Provisional; Region: PRK10681"
                     /db_xref="CDD:182644"
     misc_feature    1138594..>1138716
                     /locus_tag="Smed_4630"
                     /note="DeoR-like helix-turn-helix domain; Region:
                     HTH_DeoR; cl17531"
                     /db_xref="CDD:248085"
     misc_feature    1138846..1139280
                     /locus_tag="Smed_4630"
                     /note="DeoR C terminal sensor domain; Region: DeoRC;
                     pfam00455"
                     /db_xref="CDD:201239"
     gene            1139418..1140422
                     /locus_tag="Smed_4631"
                     /db_xref="GeneID:5319266"
     CDS             1139418..1140422
                     /locus_tag="Smed_4631"
                     /EC_number="4.1.2.4"
                     /note="TIGRFAM: deoxyribose-phosphate aldolase;
                     PFAM: deoxyribose-phosphate
                     aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase;
                     KEGG: sme:SMb21300 putative deoxyribose-phosphate aldolase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="YP_001313361.1"
                     /db_xref="GI:150376765"
                     /db_xref="InterPro:IPR002915"
                     /db_xref="InterPro:IPR011343"
                     /db_xref="GeneID:5319266"
                     /translation="MEDLALKSTAVHPAGAGDNWPRNDGVELDLSWVLDQRVNLSAAE
                     RRVQTLPGRRTVKKDAQAAWLLKAVTCIDLTTLSGDDTTERVKRLCAKARQPVRQDIL
                     DALGMGDRGITTGAICVYHRFVSTAVDALEGSGIPVAAVSTGFPAGLVPHDVKLREIE
                     ASVADGAREIDIVITREHVLTGNWQALYDEMRDFRAACGDAHVKAILATGDLKTLRNV
                     ARASLVCMMAGADFIKTSTGKEGVNATLLVTLAMLRMIRAYEERTGLKVGYKPAGGIS
                     AAKDVLNYQFLMREELGRDWLEPDLFRVGASSLLGDIERQLEHHVSGAYSALNRHPIG
                     "
     misc_feature    1139619..1140296
                     /locus_tag="Smed_4631"
                     /note="2-deoxyribose-5-phosphate aldolase (DERA) of the
                     DeoC family; Region: DeoC; cd00959"
                     /db_xref="CDD:188646"
     misc_feature    order(1139646..1139648,1139652..1139654,1139658..1139660,
                     1139778..1139786,1139850..1139852,1139874..1139876,
                     1139889..1139891,1139904..1139915,1139940..1139942,
                     1139946..1139948,1140003..1140008,1140048..1140050)
                     /locus_tag="Smed_4631"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:188646"
     misc_feature    order(1140117..1140119,1140126..1140128,1140231..1140239,
                     1140294..1140296)
                     /locus_tag="Smed_4631"
                     /note="active site"
                     /db_xref="CDD:188646"
     misc_feature    1140117..1140119
                     /locus_tag="Smed_4631"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188646"
     gene            1140427..1142811
                     /locus_tag="Smed_4632"
                     /db_xref="GeneID:5319267"
     CDS             1140427..1142811
                     /locus_tag="Smed_4632"
                     /note="PFAM: aldehyde dehydrogenase;
                     KEGG: sme:SMb21301 putatively membrane-anchored aldehyde
                     dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="YP_001313362.1"
                     /db_xref="GI:150376766"
                     /db_xref="InterPro:IPR002086"
                     /db_xref="GeneID:5319267"
                     /translation="MSVATFFDDMSYGVAPEADTEARAWLDRHEGKFGHFINGAFVAA
                     VSGKTFDTFEPATGALLAGIARGGREDVDAAVAAARKAQGPWAKLSGHARARHLYALA
                     RLIQRHARLIAVVEALDNGKPIRETRDIDVPLAARHFYHHAGWAQLQETEFADQVPVG
                     VVGQVIPWNFPFLMLAWKVAPALALGNTVILKPAEYTPLTALLFAEMAAASGLPPGVL
                     NVVTGEGETGALIVEHEDIDKIAFTGSTEIGRLIREKTAGSGKSLTLELGGKSPFIVF
                     DDADIDAAVEGVVDAIWFNQGQVCCAGSRLLVQEGVAPVFHERLKRRMDTLRVGHPLD
                     KSIDMAAIVAPVQLQRIAELVAKGVAEGASMHQPRIELPKGGSFYRPTLLTGVQPTSV
                     VATEEIFGPVAVSMTFRTPDEAIQLANHSRYGLAASVWSETIGLALHVAAKLAAGVVW
                     VNATNLFDAAAGFGGKRESGFGREGGREGCYEYLKPKAWIGRKLRAEPATPAPKTAAG
                     DFVLPVLDRTAKLFIDGKQARPDGNYSRPVLSPKGKVVGEVGEGNRKDIRNAVVAARG
                     ASGWSSATAHNRAQILYYIAENLSSRGAEFADRIAAMTGASAASARTEVEASIARLFS
                     YGAWADKYEGVVHQPPLRGVALAMPEPQGVVGVICPPEAPLLGLVSLVAPLIAVGNRV
                     IAVPSETHPLAATDFYSVLETSDVPPGVINIVTGLATELAKALAAHNDVDALWAFGSP
                     ELSTLVERLSIGNLKRTFVDYGRSIDWMDRSAAEGQVFLRRAVDVKNIWIPYGE"
     misc_feature    1140460..1141887
                     /locus_tag="Smed_4632"
                     /note="NAD(P)+-dependent aldehyde dehydrogenase
                     superfamily; Region: ALDH-SF; cl11961"
                     /db_xref="CDD:245815"
     misc_feature    1140562..1141809
                     /locus_tag="Smed_4632"
                     /note="Aldehyde dehydrogenase family; Region: Aldedh;
                     pfam00171"
                     /db_xref="CDD:215767"
     misc_feature    order(1140919..1140933,1140955..1140957,1141000..1141002,
                     1141006..1141011,1141150..1141161,1141168..1141170,
                     1141177..1141182,1141222..1141230,1141330..1141332,
                     1141615..1141617,1141621..1141623,1141699..1141701,
                     1141813..1141815)
                     /locus_tag="Smed_4632"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:143395"
     misc_feature    order(1140931..1140933,1141222..1141224,1141321..1141323,
                     1141330..1141332)
                     /locus_tag="Smed_4632"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143395"
     misc_feature    1141972..>1142694
                     /locus_tag="Smed_4632"
                     /note="NAD(P)+-dependent aldehyde dehydrogenase
                     superfamily; Region: ALDH-SF; cl11961"
                     /db_xref="CDD:245815"
     misc_feature    1141981..>1142694
                     /locus_tag="Smed_4632"
                     /note="NAD-dependent aldehyde dehydrogenases [Energy
                     production and conversion]; Region: PutA; COG1012"
                     /db_xref="CDD:223944"
     misc_feature    order(1142398..1142412,1142434..1142436,1142479..1142481,
                     1142485..1142490,1142632..1142643,1142650..1142652,
                     1142659..1142664)
                     /locus_tag="Smed_4632"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:143395"
     gene            1143097..1143552
                     /locus_tag="Smed_4633"
                     /db_xref="GeneID:5319268"
     CDS             1143097..1143552
                     /locus_tag="Smed_4633"
                     /note="PFAM: RbsD or FucU transport;
                     KEGG: sme:SMb21302 similar to protein from fucose
                     degradation operon"
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="YP_001313363.1"
                     /db_xref="GI:150376767"
                     /db_xref="InterPro:IPR007721"
                     /db_xref="GeneID:5319268"
                     /translation="MLKNIDPALNADVLHALRSMGHGDTLVISDTNFPSDAIARQTTL
                     GKLLHIDNVSAARAAKAILSVLPLDTPLQPSAGRMEVMGAPDEVPGVQREVQAEIDRA
                     EGKPAPMYGIERFAFYEEAKKAYCVITTGETRFYGCFLFTKGVVPPETI"
     misc_feature    1143097..1143543
                     /locus_tag="Smed_4633"
                     /note="Fucose dissimilation pathway protein FucU
                     [Carbohydrate transport and metabolism]; Region: FucU;
                     COG4154"
                     /db_xref="CDD:226632"
     gene            1143567..1143998
                     /locus_tag="Smed_4634"
                     /db_xref="GeneID:5319269"
     CDS             1143567..1143998
                     /locus_tag="Smed_4634"
                     /note="PFAM: OsmC family protein;
                     KEGG: sme:SMb21303 hypothetical membrane-anchored protein"
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="YP_001313364.1"
                     /db_xref="GI:150376768"
                     /db_xref="InterPro:IPR003718"
                     /db_xref="GeneID:5319269"
                     /translation="MAELKVRTRETGASAVVGRTGLPHVKSLTGGELDIVTNPSQPGF
                     GPLDLLYASLASCLVLSARIAASRFGVLDRLTEVSVKVTGEKAHDEPSRVARFDIAFI
                     IKGDFDETVRHAIAEAAEEEICTVSNTLRGGPDFVSTVSAE"
     misc_feature    1143573..1143986
                     /locus_tag="Smed_4634"
                     /note="Predicted redox protein, regulator of disulfide
                     bond formation [Posttranslational modification, protein
                     turnover, chaperones]; Region: COG1765"
                     /db_xref="CDD:224679"
     gene            1144028..1144822
                     /locus_tag="Smed_4635"
                     /db_xref="GeneID:5319270"
     CDS             1144028..1144822
                     /locus_tag="Smed_4635"
                     /note="PFAM: amidinotransferase;
                     KEGG: sme:SMb21304 putative NG,NG-dimethylarginine
                     dimethylaminohydrolase (dimethylargininase) protein"
                     /codon_start=1
                     /transl_table=11
                     /product="amidinotransferase"
                     /protein_id="YP_001313365.1"
                     /db_xref="GI:150376769"
                     /db_xref="InterPro:IPR003198"
                     /db_xref="GeneID:5319270"
                     /translation="MTRPAYQFNSIIARSPSRSVVNGLRAEDRGNPTYEGVKSEHDAY
                     VEAMRDAGVLVTLLPALEAFPDSVFVEDPALVFTEGAILLRPGAATRAKEVEEISPTL
                     HDMFDAVLDLPEGYADGGDVLTTRESVMIGLSARTDKEGAAALRACLEKLGRASEIVA
                     TPEGVLHFKTDCSLLDDETVLSTDRLARSGVFGKFRQMIIPEGEEPAANALRVNDVVM
                     VGSDFPRTIEMLDKAGYMVVPLKTTEIGKIDAGLSCMSLRWFSDRM"
     misc_feature    1144028..1144798
                     /locus_tag="Smed_4635"
                     /note="Amidinotransferase; Region: Amidinotransf; cl12043"
                     /db_xref="CDD:245848"
     misc_feature    1144046..1144804
                     /locus_tag="Smed_4635"
                     /note="N-Dimethylarginine dimethylaminohydrolase [Amino
                     acid transport and metabolism]; Region: COG1834"
                     /db_xref="CDD:224747"
     gene            complement(1144923..1146299)
                     /locus_tag="Smed_4636"
                     /db_xref="GeneID:5319271"
     CDS             complement(1144923..1146299)
                     /locus_tag="Smed_4636"
                     /EC_number="1.16.1.1"
                     /note="Enables the enzymatic reduction of mercuric ions to
                     elemental mercury"
                     /codon_start=1
                     /transl_table=11
                     /product="mercuric reductase"
                     /protein_id="YP_001313366.1"
                     /db_xref="GI:150376770"
                     /db_xref="InterPro:IPR000103"
                     /db_xref="InterPro:IPR000815"
                     /db_xref="InterPro:IPR001100"
                     /db_xref="InterPro:IPR001327"
                     /db_xref="InterPro:IPR004099"
                     /db_xref="InterPro:IPR012999"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="GeneID:5319271"
                     /translation="MNKHFDAIIIGAGQAGPSLAGRLTDAGKTVALIERKLFGGTCVN
                     TGCMPTKAMVASAYAIHTARRGAEYGMTTGPVSVDFGRVMARKEKVRLDARSGLQKWL
                     RGMTNCTLFEGHARFGGPREIRIGEELISGEQIFINVGGRAAVPALPGVNGIPYLTNS
                     SIMDLAELPEHLVIVGGSYIGLEFAQMFRRFGSDVTVIEKGPRLIGREDPEVSDAIRE
                     ILENEGIRIRTNAECIRFSQTAAGIAVGVDCTSGEPEVTGSHVLLATGRHPNTDDLGL
                     EKAGVKTDARGYIEVDDSLRTNIPHIFAMGDCNGRGAFTHTSYNDFEIVAANLLDDDP
                     RRVSDRIQTYALYIDPPLGRAGMTETEARKKGCKLLIGTRPMTRVGRAVEKGETQGFM
                     KVIVDADTKDILGASILGTGGDEAIQSILDVMYAKRPYTTISRAVHIHPTVSELIPTV
                     FGDLSPAD"
     misc_feature    complement(1144932..1146299)
                     /locus_tag="Smed_4636"
                     /note="mercuric reductase; Validated; Region: PRK06370"
                     /db_xref="CDD:235787"
     misc_feature    complement(<1146198..1146299)
                     /locus_tag="Smed_4636"
                     /note="ubiquinone biosynthesis hydroxylase family protein;
                     Provisional; Region: PRK07608; cl17314"
                     /db_xref="CDD:247868"
     misc_feature    complement(1145544..1145789)
                     /locus_tag="Smed_4636"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:215691"
     misc_feature    complement(1144953..1145267)
                     /locus_tag="Smed_4636"
                     /note="Pyridine nucleotide-disulphide oxidoreductase,
                     dimerisation domain; Region: Pyr_redox_dim; pfam02852"
                     /db_xref="CDD:217252"
     gene            1146538..1147455
                     /locus_tag="Smed_4637"
                     /db_xref="GeneID:5319282"
     CDS             1146538..1147455
                     /locus_tag="Smed_4637"
                     /note="PFAM: Substrate-binding region of ABC-type glycine
                     betaine transport system;
                     KEGG: sme:SMb21144 putative choline uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="YP_001313367.1"
                     /db_xref="GI:150376771"
                     /db_xref="InterPro:IPR007210"
                     /db_xref="GeneID:5319282"
                     /translation="MRLNFTRTLIGTAFVLALATAPAEADVVVSSKIDTEGGVLGNII
                     LSILNANDIKTTDRVQLGATPVVRKAIIAGEIDIYPEYTGNAAFFFEKAEDPAWKDAA
                     KAYEEAKKLDYEANKIVWLTPSPANNTWAIALRKDVAEKNNLKTLSDFGKYVSGGGEV
                     VLAASSEFVNSAAALPAFQTTYSFKLKPEQLITLSGGDTAATIAAAANQTNGANAAMV
                     YGTDGGIAPSGLVVLEDDKGVQPVYQPAPVIREAVLKENPAIEELLKPVFEKLDLTTL
                     QELNGRVQVGGESAKAVAEDFLKANGFLK"
     misc_feature    1146538..1147440
                     /locus_tag="Smed_4637"
                     /note="Periplasmic glycine betaine/choline-binding
                     (lipo)protein of an ABC-type transport system
                     (osmoprotectant binding protein) [Cell envelope
                     biogenesis, outer membrane]; Region: OpuBC; COG1732"
                     /db_xref="CDD:224646"
     sig_peptide     1146538..1146615
                     /locus_tag="Smed_4637"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 26"
     gene            1147533..1148732
                     /locus_tag="Smed_4638"
                     /db_xref="GeneID:5319283"
     CDS             1147533..1148732
                     /locus_tag="Smed_4638"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21145 putative choline uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313368.1"
                     /db_xref="GI:150376772"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319283"
                     /translation="MAIGIIQEKERLAFRFDKLGVIISILALYGALLAPFATYRANRI
                     IQGEARGIMEALPPHLGYGLLFLVVAGAAVALLRTPALFRMAMALAALAALAGLIGIA
                     ADHLTPPENSYARVSPASGFWVLVFAFSLLLTDALTRLNPGPGLRLLVLAGVLVLAGS
                     MLVAGRWDGLSIMKEYANRADLFWAEAGRHVTLALGSLAAATVVGLPLGILCHRVERL
                     RAGVLNVLNAIQTIPSIALFGILIAPLGWIAANIPGASAVGIRGIGAAPAFVALFLYS
                     LLPVVANTVVGLAGVPRAANDAARGIGMTDRQRLVTIEFPLAFPVILTGIRIVLVQNI
                     GLATIAALIGGGGFGVFVFQGVGQTAMDLVLLGAIPTVVLAFTAAIVLDALIEMTVPN
                     SSQGNAA"
     misc_feature    1148100..>1148525
                     /locus_tag="Smed_4638"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1148139..1148144,1148151..1148156,1148169..1148171,
                     1148196..1148207,1148211..1148240,1148247..1148252,
                     1148256..1148258,1148352..1148357,1148361..1148363,
                     1148367..1148369,1148376..1148381,1148385..1148387,
                     1148397..1148402,1148409..1148411,1148460..1148462,
                     1148502..1148507,1148514..1148516)
                     /locus_tag="Smed_4638"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    1148214..1148258
                     /locus_tag="Smed_4638"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1148412..1148450,1148466..1148471,1148481..1148483)
                     /locus_tag="Smed_4638"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1148729..1149667
                     /locus_tag="Smed_4639"
                     /db_xref="GeneID:5319284"
     CDS             1148729..1149667
                     /locus_tag="Smed_4639"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21146 putative choline uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313369.1"
                     /db_xref="GI:150376773"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319284"
                     /translation="MIQIEEVTKRYGDTTVVNGVTLTVAPHTVTVIVGTSGSGKTTLL
                     RMINRLVEPTAGIVKIDGEDNRSIPGYELRRRIGYAIQGHGLFPHRTVAQNIATVPTL
                     LGWEKDRTEAKVEELLKLFQLDPADFGPRYPHELSGGQQQRVGVARALAAEPNVLLMD
                     EPFGALDPIIRSKAQEDLAAIQKHFGTTIILVTHDMEEAFHLADKIAVMDKGEVVQYA
                     TPAEMLVKPATPFVETLVGASERPFRLLGIETVGEAVEPGSAEGRPVPEVLSQRDALS
                     ELLWSGRSALPVAAANGEILGRVTLQAIVKRAARPR"
     misc_feature    1148729..1149652
                     /locus_tag="Smed_4639"
                     /note="ABC-type proline/glycine betaine transport systems,
                     ATPase components [Amino acid transport and metabolism];
                     Region: OpuBA; COG1125"
                     /db_xref="CDD:224050"
     misc_feature    1148732..1149448
                     /locus_tag="Smed_4639"
                     /note="ATP-binding cassette domain of the osmoprotectant
                     transporter; Region: ABC_OpuCA_Osmoprotection; cd03295"
                     /db_xref="CDD:213262"
     misc_feature    1148828..1148851
                     /locus_tag="Smed_4639"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213262"
     misc_feature    order(1148837..1148842,1148846..1148854,1148972..1148974,
                     1149206..1149211,1149308..1149310)
                     /locus_tag="Smed_4639"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213262"
     misc_feature    1148963..1148974
                     /locus_tag="Smed_4639"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213262"
     misc_feature    1149134..1149163
                     /locus_tag="Smed_4639"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213262"
     misc_feature    1149194..1149211
                     /locus_tag="Smed_4639"
                     /note="Walker B; other site"
                     /db_xref="CDD:213262"
     misc_feature    1149218..1149229
                     /locus_tag="Smed_4639"
                     /note="D-loop; other site"
                     /db_xref="CDD:213262"
     misc_feature    1149296..1149316
                     /locus_tag="Smed_4639"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213262"
     gene            1149664..1150404
                     /locus_tag="Smed_4640"
                     /db_xref="GeneID:5319285"
     CDS             1149664..1150404
                     /locus_tag="Smed_4640"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21147 putative choline uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313370.1"
                     /db_xref="GI:150376774"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319285"
                     /translation="MMFTLPNLFRLAVLVVLLAFLLQPAWFEAMLTPLVQENAPAIYN
                     QGSLFWLTVLHLRTVFIATFAATVVAVSLAIIVTRKAGAEFLPLSRSLVNIGQTFPPV
                     AVLALAVPIYGFGEKPTLIALFLYGLLPIFENALTGLTTLPPTVVEAARGAGMTGSQR
                     LIRIELPLALPVILTGVRLSVVISLATATIGSTVAAKTLGEVIIAGLQSNNLAFVLQG
                     GLIVAALAVLIHDALQGLERTLAGRVHV"
     misc_feature    1149925..1150350
                     /locus_tag="Smed_4640"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1149928..1149939,1149943..1149972,1149979..1149984,
                     1149988..1149990,1150036..1150041,1150045..1150047,
                     1150051..1150053,1150060..1150065,1150069..1150071,
                     1150081..1150086,1150093..1150095,1150144..1150146,
                     1150186..1150191,1150198..1150200,1150219..1150230,
                     1150237..1150242,1150288..1150293,1150321..1150326,
                     1150333..1150338,1150342..1150347)
                     /locus_tag="Smed_4640"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1149946..1149990,1150219..1150236)
                     /locus_tag="Smed_4640"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1149988..1149990,1150021..1150023,1150237..1150239,
                     1150282..1150284,1150291..1150293,1150321..1150323)
                     /locus_tag="Smed_4640"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1150096..1150134,1150150..1150155,1150165..1150167)
                     /locus_tag="Smed_4640"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1150540..1151700
                     /locus_tag="Smed_4641"
                     /db_xref="GeneID:5319286"
     CDS             1150540..1151700
                     /locus_tag="Smed_4641"
                     /note="PFAM: oxidoreductase domain protein; Oxidoreductase
                     domain;
                     KEGG: sme:SMb21148 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain-containing protein"
                     /protein_id="YP_001313371.1"
                     /db_xref="GI:150376775"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="GeneID:5319286"
                     /translation="MKVGIIGLGFRLGYLGYVFKAIDEAFEIAGYVDPEPAGLATLTE
                     KGISAGKAYATPEELIAGETLDLLMIGSPNHLHLDHIRIGLEAGLKVFCEKPLVSTIE
                     QSLELAALLSKHGPDRLMVGLVLRYAPLYRDLRAAQAAGTLGHVVSIEAAEHIEPYHG
                     AFFMRDWRRYGRYAGSFMLEKCCHDLDLYNGVVGARPERVASFGGRKSFIPANDPTRD
                     GINDLQLFHRKPSGWRGSDRVFDSDGDIIDYQVAIIEYANGVAMNFHTNLNVPDQFRR
                     FCVMGSRGMAEGDFIRGYLDVHEVLSGKKVVEKQYAKETALSQHYGADEQMAAEIIAH
                     VRDGGPLPVSPLDALEAGILALSMDEARMKRTVVDLRPLWDRFDEALHDRAA"
     misc_feature    1150540..1151655
                     /locus_tag="Smed_4641"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:223745"
     misc_feature    1150540..1150905
                     /locus_tag="Smed_4641"
                     /note="Oxidoreductase family, NAD-binding Rossmann fold;
                     Region: GFO_IDH_MocA; pfam01408"
                     /db_xref="CDD:201778"
     gene            1151713..1152597
                     /locus_tag="Smed_4642"
                     /db_xref="GeneID:5319287"
     CDS             1151713..1152597
                     /locus_tag="Smed_4642"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21149 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313372.1"
                     /db_xref="GI:150376776"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319287"
                     /translation="MSVRRSTIIFAWILLLPAALYVTVIVAYPLVDTFILSFTDASLK
                     KTTNWVGTANYNKIFNGTFAEVILRTFVWTAFSVAIKMLIGTFGAVMLNAAVPGRALF
                     RVLTMPPWIVPMAIGIFMWGWMYNGQFGMISGLLQNWGLVDGPVAFLAHGSTAFWATI
                     ITDVWIGVPLVTLYLLASMQAIPQDLYEAAWTDGAGRFYRFRRITLPLLVPSMITMSM
                     LSLIATFNSFDIIWILTQGGPNGDTTTMIIDTYRTAIGSKKYGEGAARAVLICIFLSI
                     FCVAYFRVTHRLASGESR"
     sig_peptide     1151713..1151796
                     /locus_tag="Smed_4642"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.917) with cleavage site probability 0.773 at
                     residue 28"
     misc_feature    1151716..1152585
                     /locus_tag="Smed_4642"
                     /note="2-aminoethylphosphonate transport system permease
                     PhnU; Provisional; Region: PRK15050"
                     /db_xref="CDD:237888"
     misc_feature    1151911..1152549
                     /locus_tag="Smed_4642"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1151959..1151964,1151971..1151976,1151989..1151991,
                     1152016..1152027,1152031..1152060,1152067..1152072,
                     1152076..1152078,1152202..1152207,1152211..1152213,
                     1152220..1152222,1152229..1152234,1152238..1152240,
                     1152250..1152255,1152262..1152264,1152313..1152315,
                     1152355..1152360,1152367..1152369,1152388..1152399,
                     1152406..1152411,1152466..1152471,1152499..1152504,
                     1152511..1152516,1152520..1152525,1152532..1152537,
                     1152544..1152549)
                     /locus_tag="Smed_4642"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1152034..1152078,1152388..1152405)
                     /locus_tag="Smed_4642"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1152076..1152078,1152187..1152189,1152406..1152408,
                     1152460..1152462,1152469..1152471,1152499..1152501)
                     /locus_tag="Smed_4642"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1152265..1152303,1152319..1152324,1152334..1152336)
                     /locus_tag="Smed_4642"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1152594..1153451
                     /locus_tag="Smed_4643"
                     /db_xref="GeneID:5319288"
     CDS             1152594..1153451
                     /locus_tag="Smed_4643"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21150 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313373.1"
                     /db_xref="GI:150376777"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319288"
                     /translation="MSQPSMINRYRWYELLAIYAGIFVFLSFILAPFVEGFLVSLKPL
                     GRLFSSPYRFWPENGSFEAYRTMWVSVPGFARYIFNSFFISIIVTAVVLALVVPAAYA
                     LARFKFRGSGALLAAFLAVNMFSGAVLLIPLFRLMRSFGVLNTYFAMIVPGVAFLIPS
                     AIWLLRTYMMRIPRELDEAAFVDGASRFYTLRRVILPIAMPGITVVAITTFIGSYAQQ
                     FIFALTFNSKTEYMPLPVGLFAYFGRQEVVWNELMAASFVGIAPAVIVIFFLQRYLVS
                     GLTAGAVKQ"
     misc_feature    1152609..1153445
                     /locus_tag="Smed_4643"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    1152825..>1153235
                     /locus_tag="Smed_4643"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1152873..1152878,1152885..1152890,1152903..1152905,
                     1152933..1152944,1152948..1152977,1152984..1152989,
                     1152993..1152995,1153065..1153067,1153071..1153073,
                     1153080..1153085,1153089..1153091,1153101..1153106,
                     1153113..1153115,1153164..1153166,1153206..1153211,
                     1153218..1153220)
                     /locus_tag="Smed_4643"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    1152951..1152995
                     /locus_tag="Smed_4643"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    <1153086..1153409
                     /locus_tag="Smed_4643"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cl00427"
                     /db_xref="CDD:241857"
     misc_feature    order(1153116..1153154,1153170..1153175,1153185..1153187)
                     /locus_tag="Smed_4643"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1153481..1154710
                     /locus_tag="Smed_4644"
                     /db_xref="GeneID:5319289"
     CDS             1153481..1154710
                     /locus_tag="Smed_4644"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb21151 putative periplasmic solute-binding
                     protein of a sugar uptake ABC transporter system"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313374.1"
                     /db_xref="GI:150376778"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5319289"
                     /translation="MTIAYKATCFTLALLGSTALGGFAAQAADQEISWIYCGDKIDPI
                     HEKYIKEWEGKNPGWKVTPEVVGWAQCQDKATTLAVAGTPVGMAYVGSRTLKEFAENE
                     LIIPVPMTEEEKKSYYPNIVETVTFNDNQWGVPIAFSTKALYWNKDLFKQAGLDPETP
                     PKSWAEEIAFAKQIKEKTGIAGYGLPAKTFDNTMHQFMHWVYTNNGKVIDGDEIVMDS
                     PEVLAALQAYKDLVPYSVEGATAYEQNEIRAIFLDGKVGMIQSGSGAAALLKDTKINW
                     GIAPLPLGPSAKGEGTLLITDSLAIFQGTGVEEKAIEFAKFITSPGPQGEYELQGGAG
                     LTPLRPSPMVDEFVKADPSWKPFIDGIAYGGPEPLFKDYKGFQNAIIDMVQSVVTGKS
                     EPVDALKKAAADIEQYK"
     sig_peptide     1153481..1153564
                     /locus_tag="Smed_4644"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.993 at
                     residue 28"
     misc_feature    1153619..1154536
                     /locus_tag="Smed_4644"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_8; pfam13416"
                     /db_xref="CDD:222114"
     misc_feature    <1153883..>1154443
                     /locus_tag="Smed_4644"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; cl17199"
                     /db_xref="CDD:247753"
     gene            1154796..1155929
                     /locus_tag="Smed_4645"
                     /db_xref="GeneID:5319290"
     CDS             1154796..1155929
                     /locus_tag="Smed_4645"
                     /note="PFAM: ABC transporter related; TOBE domain protein;
                     Transport-associated OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21152 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313375.1"
                     /db_xref="GI:150376779"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005116"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5319290"
                     /translation="MGQLTLNKVQKSYGTYEVLKSIELEVGNGEFVVFVGPSGCGKST
                     LLRMIAGLDETTAGDIVIDGKRVNDLPPVRRGIAMVFQSYALYPHMSVFENIAFPLRV
                     EKMPEEKLKAKVQHAARILHLDQRLEQKPGMLSGGQRQRVAIGRAIVREPKIFLFDEP
                     LSNLDAALRADMRIELAKLHRHLKATMIYVTHDQVEAMTMADRIVVLNAGEIAQTGAP
                     LELYHKPANIFVAGFIGNPKMNFLPVTCTGVNDAGVEVDYKGQTILVPVVPRAGMTGR
                     TLTLGVRPEHIRMGDADLTLTVTPSVIERLGAHTVAYVALDGEGENYCAMLPGTLAIR
                     ADQRVKTGIGAIDCHLFDEKGMAFERRVEMTDIDMSHFDPAAA"
     misc_feature    1154796..1155884
                     /locus_tag="Smed_4645"
                     /note="glycerol-3-phosphate transporter ATP-binding
                     subunit; Provisional; Region: ugpC; PRK11650"
                     /db_xref="CDD:236947"
     misc_feature    1154805..1155443
                     /locus_tag="Smed_4645"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    1154901..1154924
                     /locus_tag="Smed_4645"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    order(1154910..1154915,1154919..1154927,1155039..1155041,
                     1155267..1155272,1155369..1155371)
                     /locus_tag="Smed_4645"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    1155030..1155041
                     /locus_tag="Smed_4645"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    1155195..1155224
                     /locus_tag="Smed_4645"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    1155255..1155272
                     /locus_tag="Smed_4645"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    1155279..1155290
                     /locus_tag="Smed_4645"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    1155357..1155377
                     /locus_tag="Smed_4645"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     misc_feature    1155633..1155848
                     /locus_tag="Smed_4645"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            1155932..1156432
                     /locus_tag="Smed_4646"
                     /db_xref="GeneID:5319291"
     CDS             1155932..1156432
                     /locus_tag="Smed_4646"
                     /note="PFAM: GCN5-related N-acetyltransferase;
                     KEGG: sme:SMb21153 putative acetyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase GCN5"
                     /protein_id="YP_001313376.1"
                     /db_xref="GI:150376780"
                     /db_xref="InterPro:IPR000182"
                     /db_xref="GeneID:5319291"
                     /translation="MGVTIRLLNSDDVETFRSIRIEALQAEPASFASSAEDWERLSGD
                     EWRRRTVDNPVFVAFQDDVPVGIAGLIRQSASKMAHRATLVMVYVRRELRGTGVAKRL
                     LNTVADHAREIGIRQMELAVSADNPAAIRFYNREGFAEVGRIPGGLLHEGREIDDVIK
                     VRRIAD"
     misc_feature    1155938..1156423
                     /locus_tag="Smed_4646"
                     /note="Sortase and related acyltransferases [Cell envelope
                     biogenesis, outer membrane]; Region: COG1247"
                     /db_xref="CDD:224168"
     misc_feature    1156094..1156291
                     /locus_tag="Smed_4646"
                     /note="N-Acyltransferase superfamily: Various enzymes that
                     characteristically catalyze the transfer of an acyl group
                     to a substrate; Region: NAT_SF; cd04301"
                     /db_xref="CDD:173926"
     misc_feature    order(1156190..1156198,1156226..1156231)
                     /locus_tag="Smed_4646"
                     /note="Coenzyme A binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173926"
     gene            1156592..1156975
                     /locus_tag="Smed_4647"
                     /db_xref="GeneID:5319292"
     CDS             1156592..1156975
                     /locus_tag="Smed_4647"
                     /note="PFAM: Glyoxalase/bleomycin resistance
                     protein/dioxygenase;
                     KEGG: sme:SMb21154 hypothetical protein, bleomycin
                     resistance protein family"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance
                     protein/dioxygenase"
                     /protein_id="YP_001313377.1"
                     /db_xref="GI:150376781"
                     /db_xref="InterPro:IPR004360"
                     /db_xref="GeneID:5319292"
                     /translation="MPETTVNVRYMVDDVQAAVAWYTKHLGFSVLSNHAPAFADVRRG
                     ALRLLLSGPLSSAGRPMPDGERPSPGGWNRIHLVVDDLAAEVERLRAAGVDFRNDVVT
                     GPGGSQILLKDPAGNFVELFQPAAR"
     misc_feature    1156613..1156954
                     /locus_tag="Smed_4647"
                     /note="This domain superfamily is found in a variety of
                     structurally related metalloproteins, including the type I
                     extradiol dioxygenases, glyoxalase I and a group of
                     antibiotic resistance proteins; Region: Glo_EDI_BRP_like;
                     cd06587"
                     /db_xref="CDD:211348"
     misc_feature    1156613..1156954
                     /locus_tag="Smed_4647"
                     /note="Glyoxalase/Bleomycin resistance protein/Dioxygenase
                     superfamily; Region: Glyoxalase; pfam00903"
                     /db_xref="CDD:216182"
     misc_feature    order(1156622..1156624,1156703..1156705,1156736..1156738,
                     1156742..1156744,1156811..1156813,1156943..1156945,
                     1156949..1156951)
                     /locus_tag="Smed_4647"
                     /note="active site"
                     /db_xref="CDD:211348"
     gene            complement(1157006..1158499)
                     /locus_tag="Smed_4648"
                     /db_xref="GeneID:5318811"
     CDS             complement(1157006..1158499)
                     /locus_tag="Smed_4648"
                     /note="PFAM: uncharacterised conserved protein UCP012702;
                     MlrC domain protein;
                     KEGG: sme:SMb21155 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313378.1"
                     /db_xref="GI:150376782"
                     /db_xref="InterPro:IPR009197"
                     /db_xref="InterPro:IPR010799"
                     /db_xref="GeneID:5318811"
                     /translation="MTAKTKTLRIFTAALATETNTFSPICIDRRAFEASLYASPGKHP
                     ETPTLCTAPITVGRRVAAEKGWILIEGTAAWADPAGLVNRRTYEDLRDEILDQLRAAL
                     PIDAVILGLHGAMVADGYEDTEGDLLQRVRELVGPEVLVCAELDPHSHLTNRRVAAAD
                     FFVFFKEFPHTDFVERAEDLWRVAVDTLEGRVTPVMSVFDCRMIDVFPTSREPMRSFV
                     DRLMQIERHDADVLSLSVVHGFMAGDVTEMGTKMLVVTNGKAEKGKALARELGLELFS
                     RRGTYRMPEIDAHQAVAQAIAAPSGPVVIADMWDNPGGGTAGDATVVLEELLARKATD
                     TAVGTIWDPMAVQICMAAGEGAEIPLRFGAKSAPGTGRPIDGIVKVIKLVRNAEMRFG
                     ESIAPFGDAAHIRLRGIDIILNTTRAQSFDPSLFSAMDIDPGSKKILVIKSTNHFYAS
                     FSKIASEILYCSAGTPYPNDPAKTPYRRARRDIWPMIADPHGPDQGV"
     misc_feature    complement(1157024..1158478)
                     /locus_tag="Smed_4648"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG5476"
                     /db_xref="CDD:227763"
     misc_feature    complement(1157639..1158478)
                     /locus_tag="Smed_4648"
                     /note="Protein of unknown function (DUF1485); Region:
                     DUF1485; pfam07364"
                     /db_xref="CDD:219386"
     misc_feature    complement(1157063..1157590)
                     /locus_tag="Smed_4648"
                     /note="MlrC C-terminus; Region: MlrC_C; pfam07171"
                     /db_xref="CDD:219319"
     gene            complement(1158506..1158991)
                     /locus_tag="Smed_4649"
                     /db_xref="GeneID:5318812"
     CDS             complement(1158506..1158991)
                     /locus_tag="Smed_4649"
                     /note="KEGG: sme:SMb21156 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313379.1"
                     /db_xref="GI:150376783"
                     /db_xref="GeneID:5318812"
                     /translation="MRDPFQNPFPGDDAARRSIWEMLVPRDIDAFLAADWSMVAEDFV
                     EESFIGIDGRREADPDKWRLTFPSLAEYRDEWLRQAQDFARQSFAEDPREAIFRTTTL
                     EDIEISGELALARKKFDGGVKKANGSFDVMKWQTVYYCRLHLSRWRVCGFTGYLPNPM
                     G"
     gene            1159107..1159496
                     /locus_tag="Smed_4650"
                     /db_xref="GeneID:5318813"
     CDS             1159107..1159496
                     /locus_tag="Smed_4650"
                     /note="PFAM: Endoribonuclease L-PSP;
                     KEGG: sme:SMb21157 putative translation initiation
                     inhibitor protein"
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease L-PSP"
                     /protein_id="YP_001313380.1"
                     /db_xref="GI:150376784"
                     /db_xref="InterPro:IPR006175"
                     /db_xref="GeneID:5318813"
                     /translation="MSIKRYGDEQTGAGGKALPFARAVEADGWLYVSGQVAMENGEII
                     EGNIVAQTHRAIGNLLAILKEAGYGVEHVVRVGVWLDDPRDFWSFNKIYQDYFGAHPP
                     ARACVQSSMMVDCKVEIDCVAYKPKDA"
     misc_feature    1159164..1159475
                     /locus_tag="Smed_4650"
                     /note="YjgF, YER057c, and UK114 belong to a large family
                     of proteins present in bacteria, archaea, and eukaryotes
                     with no definitive function. The conserved domain is
                     similar in structure to chorismate mutase but there is no
                     sequence similarity and no...; Region:
                     YjgF_YER057c_UK114_family; cd00448"
                     /db_xref="CDD:100004"
     misc_feature    order(1159164..1159169,1159176..1159178,1159182..1159184,
                     1159191..1159193,1159197..1159199,1159203..1159208,
                     1159320..1159322,1159326..1159331,1159335..1159337,
                     1159341..1159343,1159374..1159376,1159383..1159385,
                     1159410..1159433,1159458..1159460,1159464..1159466,
                     1159470..1159472)
                     /locus_tag="Smed_4650"
                     /note="homotrimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:100004"
     misc_feature    order(1159164..1159166,1159362..1159364,1159374..1159376,
                     1159416..1159418,1159458..1159460)
                     /locus_tag="Smed_4650"
                     /note="putative active site [active]"
                     /db_xref="CDD:100004"
     gene            1159517..1160380
                     /locus_tag="Smed_4651"
                     /db_xref="GeneID:5318814"
     CDS             1159517..1160380
                     /locus_tag="Smed_4651"
                     /note="PFAM: helix-turn-helix protein RpiR; sugar
                     isomerase (SIS);
                     KEGG: sme:SMb21158 putative transcriptional regulator,
                     probably of sugar phosphate metabolism protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RpiR family transcriptional regulator"
                     /protein_id="YP_001313381.1"
                     /db_xref="GI:150376785"
                     /db_xref="InterPro:IPR000281"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001347"
                     /db_xref="GeneID:5318814"
                     /translation="MDIFATLQEEKGRLSQSENRIADILLNDFEFAVNASIIELAGKA
                     DVSPPTVTRFCRRLGCESFSDFKVQLARTPYVGMRYLKPEPKSQEPGDVAQDIITKAQ
                     NALLLLHRSLDLAAIERAADQLAQAEMIYAFGSGGNSSMIAGEFQNRLFRLGMRITSS
                     SDHSMQMMMAAAARPADVIVGSSFSGRNAELVRAFILAREAKVPTIALTQSGSPVAQA
                     ADITVPVDLPEGNNIYRPTSTRIAYLALLDIVASLVAYRVQPQATVTLRRIKQQLVVH
                     RDGDDRQLMGD"
     misc_feature    1159517..1160347
                     /locus_tag="Smed_4651"
                     /note="Transcriptional regulators [Transcription]; Region:
                     RpiR; COG1737"
                     /db_xref="CDD:224651"
     misc_feature    1159517..1159729
                     /locus_tag="Smed_4651"
                     /note="Helix-turn-helix domain, rpiR family; Region:
                     HTH_6; pfam01418"
                     /db_xref="CDD:201784"
     misc_feature    1159865..1160275
                     /locus_tag="Smed_4651"
                     /note="RpiR-like protein. RpiR contains a SIS (Sugar
                     ISomerase) domain, which is found in many phosphosugar
                     isomerases and phosphosugar binding proteins. In E. coli,
                     rpiR negatively regulates the expression of rpiB gene.
                     Both rpiB and rpiA are ribose phosphate...; Region:
                     SIS_RpiR; cd05013"
                     /db_xref="CDD:240144"
     misc_feature    order(1159931..1159933,1160063..1160065)
                     /locus_tag="Smed_4651"
                     /note="putative active site [active]"
                     /db_xref="CDD:240144"
     gene            1160382..1161176
                     /locus_tag="Smed_4652"
                     /db_xref="GeneID:5318815"
     CDS             1160382..1161176
                     /locus_tag="Smed_4652"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR; KR
                     domain protein;
                     KEGG: sme:SMb21159 short chain dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="short chain dehydrogenase"
                     /protein_id="YP_001313382.1"
                     /db_xref="GI:150376786"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR002424"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5318815"
                     /translation="MPQGTPIPKSVAIVTGAAGDIGRAIARRLRDGHDTVLLADIEGE
                     AAERTARDLGGAERFVAVTCDVTDTASVSAMARAAASFGTVRTLVNNAGAARAVSLHD
                     TTQDTWRADNALNLEAAFLCFRAVEEMLKESRGAVVNIASVNGMNVFGHPAYSAAKAG
                     LLHLTRLIAVEYGKFGIRANAVAPATVRTRAWEARAAANPDVFEEAKRWYPLQRIVDP
                     QDVAEAVHFLASPAAGAISGICLPVDCGLTAGHAEVARTFTQSIHY"
     misc_feature    1160403..1161170
                     /locus_tag="Smed_4652"
                     /note="short chain dehydrogenase; Provisional; Region:
                     PRK07074"
                     /db_xref="CDD:180823"
     misc_feature    1160484..1161113
                     /locus_tag="Smed_4652"
                     /note="classical (c) SDRs; Region: SDR_c; cd05233"
                     /db_xref="CDD:212491"
     misc_feature    order(1160499..1160507,1160571..1160579,1160652..1160660,
                     1160721..1160723,1160799..1160807,1160841..1160843,
                     1160853..1160855,1160931..1160942,1160946..1160951)
                     /locus_tag="Smed_4652"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:212491"
     misc_feature    order(1160724..1160726,1160805..1160807,1160841..1160843,
                     1160853..1160855)
                     /locus_tag="Smed_4652"
                     /note="active site"
                     /db_xref="CDD:212491"
     gene            1161201..1163120
                     /locus_tag="Smed_4653"
                     /db_xref="GeneID:5318816"
     CDS             1161201..1163120
                     /locus_tag="Smed_4653"
                     /EC_number="3.2.1.52"
                     /note="PFAM: glycoside hydrolase family 20;
                     KEGG: sme:SMb21160 putative glycosyl hydrolase, similar to
                     beta-N-acetylhexosaminidases protein"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="YP_001313383.1"
                     /db_xref="GI:150376787"
                     /db_xref="InterPro:IPR001540"
                     /db_xref="GeneID:5318816"
                     /translation="MLQAAYRLESAWQPDGGPFGRFTFSLFNLSGEPLSDFRLVYTSL
                     TRVIDPDACENAVFLRRNANFHEFAPPEGLTLAHGEHWTFMISGLHRQAKHCTDGAKS
                     AYLTLADGSHVAVAVSDLRLEGAVSEPPPERLPEGWLDLPFALQPWPAEIDAAPGDLL
                     PDFLYPAAGSAADEIEAVSNVLALFHRLFSAGHAPFSLAPSSQGRPIMFKKAAELGGE
                     AYRLHFSDEEIRLDYGAAAGRQYGLTSLAQLIDGARNHAGSFSFPVSGVIADGPRYGW
                     RGCHLDVSRQFYPTADILRLIDILAWFKLNIFHWHLTDDEAWRLEIKAYPTLTTLGVM
                     RGPDEPMLPQLGNGAEPVGGFYSQEEAKAIVAHAAALSIEVVPEIDIPGHSTAALVAI
                     AELSDGQEAPESYHSVQGYPNNALNPAIPLTYEFLEKVFDEMVELFPSRYIHVGGDEV
                     ADGSWLASPLARKLMEQEGISGTFALQSYFLKKVKQMLTARGRKLVGWNEVAHGGGVG
                     TKDTLLMAWENPKVGIELAREGYDVVMTPGQAYYLDMAQADAWQEPGASWAGTATPSH
                     TYAYEAEGEFPKELKSRMKGVQACIWSEHFLSRGYFNRLVFPRLPAIAEAAWTPKDKK
                     DWLRFAAIAPLSPVL"
     misc_feature    1162020..1163099
                     /locus_tag="Smed_4653"
                     /note="The chitobiase of Serratia marcescens is a
                     beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase
                     family 20 (GH20) domain that hydrolyzes the
                     beta-1,4-glycosidic linkages in oligomers derived from
                     chitin.  Chitin is degraded by a two step process: i)...;
                     Region: GH20_chitobiase-like; cd06563"
                     /db_xref="CDD:119333"
     misc_feature    1162020..1163063
                     /locus_tag="Smed_4653"
                     /note="Glycosyl hydrolase family 20, catalytic domain;
                     Region: Glyco_hydro_20; pfam00728"
                     /db_xref="CDD:216086"
     misc_feature    order(1162053..1162055,1162350..1162352,1162542..1162547,
                     1162692..1162694,1162749..1162751,1162824..1162826,
                     1162830..1162832,1162974..1162976,1162980..1162982)
                     /locus_tag="Smed_4653"
                     /note="active site"
                     /db_xref="CDD:119333"
     gene            1163132..1164565
                     /locus_tag="Smed_4654"
                     /db_xref="GeneID:5318817"
     CDS             1163132..1164565
                     /locus_tag="Smed_4654"
                     /note="PFAM: uncharacterised conserved protein UCP012702;
                     MlrC domain protein;
                     KEGG: sme:SMb21161 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="MlrC domain-containing protein"
                     /protein_id="YP_001313384.1"
                     /db_xref="GI:150376788"
                     /db_xref="InterPro:IPR009197"
                     /db_xref="InterPro:IPR010799"
                     /db_xref="GeneID:5318817"
                     /translation="MRIAVGGIHTECSTYSPVLMTVEDFRVLRGEDLLNSDYFGFLSA
                     EGIDHLPLLHARAVPGGPVSRPAYDALKSEFLERLKAALPLDGLYLAMHGAIKVDGMD
                     DAEGDWISAARAIVGASCPLAVSYDLHGNVSQRIIDQIDIFAAYRTAPHIDTRETMMR
                     SWSMLVEALRSGTRPGVAWARVPLLLPGERTSTEDEPAAGLYRGLADINRRPGILDAN
                     LMVGYVWADEPRATACAVVTGADKEAATKAVEEIAASYWFNREEFRFGSISGSLAQML
                     GIAESAKTAPVILADSGDNPTGGGVGDRADVLIALIERGWRDALIAGIADRPAVDACF
                     AAGTGGILKFRVGGSLDTSSPSAEIEAKVVRLDDPGPATERQAVVEAAGIEIVLSARR
                     RPYHNIEDFTRLGLDPRGVRLLIVKSGYLSPELAPIANPSLMALTDGVVNQEIEKLAS
                     LRRERPIFPFDRDFEFRPSARLSARWI"
     misc_feature    1163132..1164541
                     /locus_tag="Smed_4654"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG5476"
                     /db_xref="CDD:227763"
     misc_feature    1163132..1163953
                     /locus_tag="Smed_4654"
                     /note="Protein of unknown function (DUF1485); Region:
                     DUF1485; pfam07364"
                     /db_xref="CDD:219386"
     misc_feature    1163993..1164490
                     /locus_tag="Smed_4654"
                     /note="MlrC C-terminus; Region: MlrC_C; pfam07171"
                     /db_xref="CDD:219319"
     gene            1164633..1165844
                     /locus_tag="Smed_4655"
                     /db_xref="GeneID:5318818"
     CDS             1164633..1165844
                     /locus_tag="Smed_4655"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: sme:SMb21162 putative integral membrane transporter
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001313385.1"
                     /db_xref="GI:150376789"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5318818"
                     /translation="MPSSLLIAMRNPVIRTSMFAIVLFGFSGAATSPYQSVVGITELG
                     LSDGLYSALIFAAALVNVALSVTIGIVADRVGNYRTLMLAVILCGVAGYGAVYLLPTK
                     LSFVLAALILLPAYGALNPLLFAYVRTAAKDMGGRHAAAVNSAIRAAISLSWVLVPGL
                     VGLVLSAHGSMLPAYLLASLGCLANFVLVLRRLPPKAAVDQALGKRLSFLASFGEILS
                     LRVVLRLLAIALISSTLHVNAAVLPLIVTGAVGGDVGDIGIIVGIVALLEVIFILVWG
                     RIQDSLSHINALALGTAIYVVNMALLGLSAERWHIYALTLVSAFGAAALISIPITYLQ
                     ELIADRPGLGSSLISVNIFLGAGLGAALFALGTRISDYSGTALLSSLAGVAGLSLLLF
                     LDGGRGKASAL"
     sig_peptide     1164633..1164722
                     /locus_tag="Smed_4655"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.934) with cleavage site probability 0.569 at
                     residue 30"
     gene            complement(1165915..1167594)
                     /locus_tag="Smed_4656"
                     /db_xref="GeneID:5318819"
     CDS             complement(1165915..1167594)
                     /locus_tag="Smed_4656"
                     /EC_number="4.2.1.49"
                     /note="catalyzes the formation of
                     4-imidazolone-5-propanoate from urocanate during histidine
                     metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="YP_001313386.1"
                     /db_xref="GI:150376790"
                     /db_xref="InterPro:IPR000193"
                     /db_xref="GeneID:5318819"
                     /translation="MNMNNPRHNIREVRSPRGTEISARSWLTEAPLRMLMNNLDPDVA
                     ENPHELVVYGGIGRAARTWADFDRIVASLRYLNEDETLLVQSGKPVGVFRTHRDAPRV
                     LIANSNLVPHWANWDHFNELDKKGLAMYGQMTAGSWIYIGTQGIVQGTYETFVEAGRQ
                     HYGGSLKGKWILTGGLGGMGGAQPLAAVMAGACCLAVECNPDSIDFRLRTRYLDEKAE
                     TLEEAMEMIERWTKAGEAKSVGLLGNAAEILPQMVRRGIRPDIVTDQTSAHDPVNGYL
                     PKGWTIAEWKAKRESDPKTVEKAARASMRDHVEAMLAFWDSGIPTLDYGNNIRQVAKD
                     EGLERAFDFPGFVPAYIRPLFCRGIGPFRWAALSGDPEDIYKTDQKVKELLPDNKHLH
                     NWLDMARERIAFQGLPARICWVGLGDRHRLGLAFNEMVRSGELKAPIVIGRDHLDSGS
                     VASPNRETEAMKDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIC
                     CDGTDDAARRVERVLWNDPATGVMRHADAGYDIALDCAREKGLRLPGILGE"
     misc_feature    complement(1165927..1167591)
                     /locus_tag="Smed_4656"
                     /note="urocanate hydratase; Provisional; Region: PRK05414"
                     /db_xref="CDD:235448"
     gene            complement(1167591..1168406)
                     /locus_tag="Smed_4657"
                     /db_xref="GeneID:5318820"
     CDS             complement(1167591..1168406)
                     /locus_tag="Smed_4657"
                     /note="PFAM: N-formylglutamate amidohydrolase;
                     KEGG: sme:SMb21164 putative formiminoglutamase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="N-formylglutamate amidohydrolase"
                     /protein_id="YP_001313387.1"
                     /db_xref="GI:150376791"
                     /db_xref="InterPro:IPR007709"
                     /db_xref="InterPro:IPR010247"
                     /db_xref="GeneID:5318820"
                     /translation="MAVFEVRRGNSPVILGFPHTGTDLPSSIWERLNDNGRILADTDW
                     HIHELYEGLLPGATTVRATFHRYVIDANRDPDGVSLYPGQNTTGLVPESDFDGQPIWK
                     EGQGPAEADIAERLRDFHAPYHAALAAEIARVRAIHGIAVLYDCHSIRSHIPFLFEGT
                     LPDFNIGTDRGKTCALEIERSVEEIASETEGYSHTLNGRFKGGWTTRHYGRPEQGVHA
                     IQMELAQSTHLATEAPPFALDAAKAERLRRPLAAILERIGKIANELKRTGSEA"
     misc_feature    complement(1167618..1168400)
                     /locus_tag="Smed_4657"
                     /note="N-formylglutamate amidohydrolase; Region: FGase;
                     cl01522"
                     /db_xref="CDD:242555"
     gene            complement(1168408..1169943)
                     /locus_tag="Smed_4658"
                     /db_xref="GeneID:5318821"
     CDS             complement(1168408..1169943)
                     /locus_tag="Smed_4658"
                     /EC_number="4.3.1.3"
                     /note="catalyzes the degradation of histidine to urocanate
                     and ammmonia"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="YP_001313388.1"
                     /db_xref="GI:150376792"
                     /db_xref="InterPro:IPR001106"
                     /db_xref="InterPro:IPR005921"
                     /db_xref="GeneID:5318821"
                     /translation="MTIILRPGSVPLSDLETIYWTGAPARLDPAFDAGVAKAAARIAE
                     IVAGNAPVYGINTGFGKLASIKIDSADVETLQRNLILSHCCGVGQPLTENIVRLIMAL
                     KLISLGRGASGVRLELVRLLEAMLDKGVIPLIPEKGSVGASGDLAPLAHMAAVMMGHG
                     EAFYAGERMAGAAALRAAGLSPVTLAAKEGLALINGTQVSTALALAGLFRAHRAGQAA
                     LITGALSTDAAMGSSAPFHPDIHTLRGHKGQIDTAAALRHLLTGSPIRQSHIEGDERV
                     QDPYCIRCQPQVDGACLDLLRSVAATLTIEANAVTDNPLVLSDNSVVSGGNFHAEPVA
                     FAADQIALAVCEIGAIAQRRIALLVDPALSYGLPAFLAKKPGLNSGLMIAEVTSAALM
                     SENKQLSHPASVDSTPTSANQEDHVSMACHGARRLLQMTDNLFAIVGIEALAAVQGIE
                     FRAPLTTSPELQKAAAAVRSISPSIEEDRYMADDLKAAAYLVASGQLAAAVSAGILPK
                     LEN"
     misc_feature    complement(1168588..1169922)
                     /locus_tag="Smed_4658"
                     /note="Phenylalanine ammonia-lyase (PAL) and histidine
                     ammonia-lyase (HAL); Region: PAL-HAL; cd00332"
                     /db_xref="CDD:176460"
     misc_feature    complement(order(1168972..1168974,1169005..1169007,
                     1169095..1169097,1169104..1169106,1169359..1169361,
                     1169371..1169385,1169707..1169709,1169716..1169718,
                     1169767..1169769,1169773..1169775,1169779..1169787))
                     /locus_tag="Smed_4658"
                     /note="active sites [active]"
                     /db_xref="CDD:176460"
     misc_feature    complement(order(1168645..1168650,1168657..1168659,
                     1168666..1168671,1168687..1168689,1168696..1168716,
                     1168747..1168758,1168762..1168779,1168783..1168785,
                     1168789..1168800,1168804..1168809,1168813..1168818,
                     1168855..1168857,1168864..1168866,1168873..1168875,
                     1168885..1168887,1168897..1168899,1168906..1168908,
                     1168927..1168929,1168939..1168941,1168948..1168953,
                     1168957..1168977,1168981..1168983,1168993..1169001,
                     1169014..1169019,1169026..1169031,1169038..1169043,
                     1169050..1169052,1169059..1169064,1169080..1169085,
                     1169092..1169097,1169101..1169109,1169113..1169115,
                     1169197..1169199,1169206..1169208,1169212..1169217,
                     1169224..1169229,1169482..1169484,1169491..1169493,
                     1169530..1169535,1169617..1169619,1169680..1169703,
                     1169710..1169712,1169767..1169772))
                     /locus_tag="Smed_4658"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176460"
     gene            complement(1169940..1171187)
                     /locus_tag="Smed_4659"
                     /db_xref="GeneID:5319334"
     CDS             complement(1169940..1171187)
                     /locus_tag="Smed_4659"
                     /EC_number="3.5.2.7"
                     /note="catalyzing the hydrolysis of
                     4-imidazolone-5-propionate to N-formimidoyl-L-glutamate,
                     the third step in the histidine degradation pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="YP_001313389.1"
                     /db_xref="GI:150376793"
                     /db_xref="InterPro:IPR005920"
                     /db_xref="InterPro:IPR006680"
                     /db_xref="InterPro:IPR011550"
                     /db_xref="InterPro:IPR013108"
                     /db_xref="GeneID:5319334"
                     /translation="MDRNDNPGPVRTSLWRNARLATLREDLGTLGVVESGVVAARGER
                     IVYAGPEAGLTSELARADQIFDCEGRWVTPALIDCHTHIVHGGNRAREFQLRLEGATY
                     EAIARAGGGIASTVEATNALSVDELVAAALPRLDALLAEGVSTVEVKSGYGLNVETEL
                     KMLRAARRLETLRPVRIVTSYLAAHATPPGYQGRNGDYIAEVVLPGLAAAHTEGLVDA
                     VDGFCEGIAFSPAEIALVFDKAKSLGLPVKLHAEQLSDLGGAKLAASYSALSADHLEY
                     LDAAGAAAMAKAGTVAVLLPGAFYTLREKQLPPVEALRAAGTRMAIATDCNPGTSPLT
                     SLLLTMNMSATLFRLTLEECLAGVTREAARALGVLDETGTIEAGKSADLAIWNIDQPA
                     ELIYRVGFNPLCERVFKGERVSR"
     misc_feature    complement(1169943..1171163)
                     /locus_tag="Smed_4659"
                     /note="imidazolonepropionase; Validated; Region: PRK09356"
                     /db_xref="CDD:236478"
     misc_feature    complement(1169958..1171076)
                     /locus_tag="Smed_4659"
                     /note="Imidazolonepropionase/imidazolone-5-propionate
                     hydrolase (Imidazolone-5PH) catalyzes the third step in
                     the histidine degradation pathway, the hydrolysis of
                     (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to
                     N-formimidoyl-L-glutamate. In bacteria; Region:
                     Imidazolone-5PH; cd01296"
                     /db_xref="CDD:238621"
     misc_feature    complement(order(1170213..1170215,1170369..1170371,
                     1170429..1170431,1170438..1170440,1170942..1170944,
                     1170948..1170950))
                     /locus_tag="Smed_4659"
                     /note="active site"
                     /db_xref="CDD:238621"
     gene            complement(1171408..1172592)
                     /locus_tag="Smed_4660"
                     /db_xref="GeneID:5319335"
     CDS             complement(1171408..1172592)
                     /locus_tag="Smed_4660"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: sme:SMb21168 putative integral membrane transporter
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001313390.1"
                     /db_xref="GI:150376794"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5319335"
                     /translation="MDKRLIWLAVGSFTMSTVGFVFSSLLPSIAADTHTTIPRAGHLI
                     TLFALSYAIGAPLLSALAGAADRRRLLVAAMLTFVVGNCIAATSVSFATLLFAQIVMG
                     MASGLFAATAQATAVSLAGAEHRALAISIVVGGTTFAVALGAPLGALIAAFWGWRGTF
                     GAIALLGLSCAAVLWLRLPRGLSGTKLTMSERFGAIGRPGVASSLSVTFLYLTGGFMI
                     ISYLAPLAIDGAGLSQLALPGLLLAFGVGAVIGNLSSGYLADRLGATRVVTASLISAL
                     VVSLMIATGLHLLTRDLAGLLLIGIMVPWGIVGWAFPPAQASRIVGFAPEVAHLTLSL
                     NASAIYLGIATGTAIGGRVLENTAAADLGFFAALFPVASLAVLYAGLRSHRRRLATVA
                     AE"
     misc_feature    complement(1171426..1172592)
                     /locus_tag="Smed_4660"
                     /note="Arabinose efflux permease [Carbohydrate transport
                     and metabolism]; Region: AraJ; COG2814"
                     /db_xref="CDD:225371"
     sig_peptide     complement(1172500..1172592)
                     /locus_tag="Smed_4660"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.997) with cleavage site probability 0.940 at
                     residue 31"
     gene            1172681..1173052
                     /locus_tag="Smed_4661"
                     /db_xref="GeneID:5319336"
     CDS             1172681..1173052
                     /locus_tag="Smed_4661"
                     /note="PFAM: regulatory protein ArsR;
                     KEGG: sme:SMb21169 putative transcriptional regulator,
                     ArsR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein ArsR"
                     /protein_id="YP_001313391.1"
                     /db_xref="GI:150376795"
                     /db_xref="InterPro:IPR001845"
                     /db_xref="GeneID:5319336"
                     /translation="MTLPHPTPDQIALSNVLAALGDPTRLAIVGYLASRDGRPTMCLN
                     FTTFGSKTNISYHLAKLREAGITRTEVSGTSRLITLRRDDLDIRFPGLLDPIIAAAMD
                     LPMVKMIEDAEKDALAKGEPG"
     misc_feature    1172729..1172932
                     /locus_tag="Smed_4661"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cd00090"
                     /db_xref="CDD:238042"
     misc_feature    order(1172729..1172734,1172738..1172740,1172747..1172749,
                     1172756..1172761,1172768..1172773,1172780..1172782,
                     1172873..1172875)
                     /locus_tag="Smed_4661"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    order(1172732..1172737,1172747..1172755,1172819..1172827,
                     1172828..1172839,1172843..1172848,1172855..1172860,
                     1172864..1172869,1172885..1172893,1172906..1172914)
                     /locus_tag="Smed_4661"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238042"
     gene            complement(1173098..1173685)
                     /locus_tag="Smed_4662"
                     /db_xref="GeneID:5319337"
     CDS             complement(1173098..1173685)
                     /locus_tag="Smed_4662"
                     /note="TIGRFAM: phosphonate metabolism
                     protein/1,5-bisphosphokinase (PRPP-forming) PhnN;
                     SMART: guanylate kinase/L-type calcium channel region;
                     KEGG: sme:SMb21170 putative guanylate kinase, also similar
                     to E. coli PhnN protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism
                     protein/1,5-bisphosphokinase (PRPP-forming) PhnN"
                     /protein_id="YP_001313392.1"
                     /db_xref="GI:150376796"
                     /db_xref="InterPro:IPR008145"
                     /db_xref="InterPro:IPR012699"
                     /db_xref="GeneID:5319337"
                     /translation="MTAAEQGTGTLIVVVGPSGAGKDSVMGFAARHFAERPDILFVRR
                     VITRPSDAGSEVHESVSDAEFEEMRRSGIFAVFWRAHGLSYGIPAEISEKVAAGMTAI
                     VNGSRAALPAIRQAFGKIAVVVITADLPVLARRLAERGRESEEDVLRRLTRQAPDLIA
                     EPDVTVIDNSDRLEIAGRQFVALVERHSARSHHPA"
     misc_feature    complement(1173101..1173664)
                     /locus_tag="Smed_4662"
                     /note="Uncharacterized component of phosphonate metabolism
                     [Inorganic ion transport and metabolism]; Region: COG3709"
                     /db_xref="CDD:226232"
     misc_feature    complement(1173173..1173661)
                     /locus_tag="Smed_4662"
                     /note="Guanylate kinase; Region: Guanylate_kin; pfam00625"
                     /db_xref="CDD:201353"
     misc_feature    complement(order(1173614..1173625,1173638..1173640))
                     /locus_tag="Smed_4662"
                     /note="active site"
                     /db_xref="CDD:238977"
     gene            complement(1173682..1174821)
                     /locus_tag="Smed_4663"
                     /db_xref="GeneID:5319338"
     CDS             complement(1173682..1174821)
                     /locus_tag="Smed_4663"
                     /note="TIGRFAM: phosphonate metabolism protein PhnM;
                     PFAM: amidohydrolase; Amidohydrolase 3;
                     KEGG: sme:SMb21171 putative enzyme protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein PhnM"
                     /protein_id="YP_001313393.1"
                     /db_xref="GI:150376797"
                     /db_xref="InterPro:IPR006680"
                     /db_xref="InterPro:IPR011550"
                     /db_xref="InterPro:IPR012696"
                     /db_xref="InterPro:IPR013108"
                     /db_xref="GeneID:5319338"
                     /translation="MPKEQVLTNARIVLEDRIVDGSVLIRDGKIADISEGASAAGEDF
                     EGDYLLPGLVELHTDHLEAHYSPRPGVRWLKIAAIQAHDAQVVTSGITTVFDCLRLGS
                     DEDSGFPKGEMRSMADALAQAKQEGRLRADHLIHLRCEVSTADVLEHYEDFRSDPQVR
                     LVSLMDHAPGQRQFQTMDQYTLYYKTKRGLTDDAFASFIERQQALSARYATPHRTALA
                     KACAERGITIASHDDATIEHVDESIGYGIRLAEFPTSFEAAEASHRAGLSVLMGAPNI
                     VRGKSHSGNIAARDLAERGVLDVLSSDYVPFSLIHAPFILADEVESIGLPEAIAMVTA
                     TPARTVGLDDRGRIAVGLRADLARVRRPEGIPVVRSVWREGRRVA"
     misc_feature    complement(1173685..1174809)
                     /locus_tag="Smed_4663"
                     /note="Metal-dependent hydrolase involved in phosphonate
                     metabolism [Inorganic ion transport and metabolism];
                     Region: COG3454"
                     /db_xref="CDD:225985"
     misc_feature    complement(<1174648..1174806)
                     /locus_tag="Smed_4663"
                     /note="Superfamily of metallo-dependent hydrolases (also
                     called amidohydrolase superfamily) is a large group of
                     proteins that show conservation in their 3-dimensional
                     fold (TIM barrel) and in details of their active site. The
                     vast majority of the members have a...; Region:
                     metallo-dependent_hydrolases; cl00281"
                     /db_xref="CDD:241750"
     misc_feature    complement(1173697..1174674)
                     /locus_tag="Smed_4663"
                     /note="PhnM is believed to be a subunit of the membrane
                     associated C-P lyase complex. C-P lyase is thought to
                     catalyze the direct cleavage of inactivated C-P bonds to
                     yield inorganic phosphate and the corresponding
                     hydrocarbons. It is responsible for cleavage...; Region:
                     PhnM; cd01306"
                     /db_xref="CDD:238631"
     misc_feature    complement(order(1173913..1173915,1174129..1174131,
                     1174645..1174647,1174651..1174653))
                     /locus_tag="Smed_4663"
                     /note="active site"
                     /db_xref="CDD:238631"
     gene            complement(1174823..1175530)
                     /locus_tag="Smed_4664"
                     /db_xref="GeneID:5319339"
     CDS             complement(1174823..1175530)
                     /locus_tag="Smed_4664"
                     /note="PFAM: protein of unknown function DUF1045;
                     KEGG: rle:RL0165 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313394.1"
                     /db_xref="GI:150376798"
                     /db_xref="InterPro:IPR009389"
                     /db_xref="GeneID:5319339"
                     /translation="MRYAIYFAPPSDDRLSQTASRWLGRDAFTGGALDCPENPALGRE
                     DQMVLTAEPRRYGFHGTLKAPFELTPQRSEADLIAAFDEFAAEIEPFEVPSIALHQIG
                     PFFALVSAKACPELQHLAEQAVRRFEPFRAALSEADLARRNPERLTQRQREYLAAWGY
                     PYVFDEFQFHLTLTGPVPEEMHRPMRKALETVFAEFIGKRLAVSTIALFAEERRGAPF
                     TVHSLLPLGGASERKIA"
     misc_feature    complement(1174847..1175530)
                     /locus_tag="Smed_4664"
                     /note="putative phosphonate metabolism protein; Region:
                     Phn_opern_protn; TIGR03223"
                     /db_xref="CDD:234147"
     gene            complement(1175869..1177380)
                     /locus_tag="Smed_4665"
                     /db_xref="GeneID:5319340"
     CDS             complement(1175869..1177380)
                     /locus_tag="Smed_4665"
                     /note="TIGRFAM: phosphonate ABC transporter, inner
                     membrane subunit;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb21174 phosphate uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter inner membrane
                     subunit"
                     /protein_id="YP_001313395.1"
                     /db_xref="GI:150376799"
                     /db_xref="InterPro:IPR000169"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR005769"
                     /db_xref="GeneID:5319340"
                     /translation="MIASTNLDASEMDAIAARHPHLLKSSAAKWRRTALISAGVVIYM
                     IFSWWFFSIGHVLANANWGIAGTYLADWVSYEVRPEIAIEPDGAMHVSFGRNSPLGDN
                     PDPEWVSLEKETVTRTVAAPAAAAQKPKSASSFSFMAPNAARGSAEATPQETVAATRT
                     EEVVTHAVVTIGRSTRIEAAEKRVTITHGGDTLTLKVDGSDNVTPEGVLPSWAIQKRP
                     GEKVTLSFGATGWAEVEGDEISIRNRFFGWVNFFFDTNSPFFGKSYGEVLSLISSGER
                     IDPARSNLSLAWDNILYNAEWQHLDVWTKLLQTVVMAFVGTLFASFIAFPLCFLAARN
                     ITPSRITNQVVKRFFDFLRSVDMFIWALFFTRAFGPGPLAGMSAIFFTDTGTLGKLYS
                     EALENIDDKQREGVKSVGAAPVAVQRFGVLPQVLPVFASQALYFWESNTRSATIIGAV
                     GAGGIGLKLWEAMRTNSDWENVAYMVLLILIVVFVFDSISNICRSRLMGRKAH"
     misc_feature    complement(1175884..1176807)
                     /locus_tag="Smed_4665"
                     /note="ABC-type phosphate/phosphonate transport system,
                     permease component [Inorganic ion transport and
                     metabolism]; Region: COG3639"
                     /db_xref="CDD:226165"
     misc_feature    complement(<1176076..1176465)
                     /locus_tag="Smed_4665"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1176076..1176078,1176085..1176090,
                     1176130..1176132,1176181..1176183,1176190..1176195,
                     1176205..1176207,1176211..1176216,1176223..1176225,
                     1176229..1176231,1176235..1176240,1176286..1176288,
                     1176292..1176297,1176304..1176333,1176337..1176348,
                     1176385..1176387,1176400..1176405,1176412..1176417))
                     /locus_tag="Smed_4665"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(1176286..1176330)
                     /locus_tag="Smed_4665"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1176109..1176111,1176121..1176126,
                     1176142..1176180))
                     /locus_tag="Smed_4665"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1177390..1178352)
                     /locus_tag="Smed_4666"
                     /db_xref="GeneID:5319341"
     CDS             complement(1177390..1178352)
                     /locus_tag="Smed_4666"
                     /note="TIGRFAM: phosphonate ABC transporter, inner
                     membrane subunit;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb21175 phosphate uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter inner membrane
                     subunit"
                     /protein_id="YP_001313396.1"
                     /db_xref="GI:150376800"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR005769"
                     /db_xref="GeneID:5319341"
                     /translation="MVTSVPTRHLSENGALIERHWQELNNRRRLYTWLGLAILALTLF
                     GSLWFANHSNAGKFFDRLPHFFDFVGHLMPRDPIEIGRALFDLPSPYDDGSFKYNYPE
                     GRLYLTESLYIPEYVHKMLETVNIAIFSTVIGVFFGFILCFLAARNLMPNPWVRGIVR
                     RLMEILRAFPEVVIAGFFLAILSLGPIPAIAAVSIHTIGALGKLFFEVVENADMKPEE
                     GLRAVGANWIERVWFGMVPQVLPNFTSYFLLRLEINVRASTIIGAVGGGGIGELLRLS
                     IGQGHEAKTLAIVLLLFATILAVDQFSAWLRRRLVGDQAFQLAQ"
     misc_feature    complement(1177417..1178307)
                     /locus_tag="Smed_4666"
                     /note="ABC-type phosphate/phosphonate transport system,
                     permease component [Inorganic ion transport and
                     metabolism]; Region: COG3639"
                     /db_xref="CDD:226165"
     misc_feature    complement(<1177600..1177995)
                     /locus_tag="Smed_4666"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1177606..1177608,1177615..1177620,
                     1177660..1177662,1177711..1177713,1177720..1177725,
                     1177735..1177737,1177741..1177746,1177753..1177755,
                     1177759..1177761,1177765..1177770,1177816..1177818,
                     1177822..1177827,1177834..1177863,1177867..1177878,
                     1177915..1177917,1177930..1177935,1177942..1177947))
                     /locus_tag="Smed_4666"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(1177816..1177860)
                     /locus_tag="Smed_4666"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1177639..1177641,1177651..1177656,
                     1177672..1177710))
                     /locus_tag="Smed_4666"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1178508..1179413)
                     /locus_tag="Smed_4667"
                     /db_xref="GeneID:5319342"
     CDS             complement(1178508..1179413)
                     /locus_tag="Smed_4667"
                     /note="TIGRFAM: phosphonate ABC transporter, periplasmic
                     phosphonate-binding protein;
                     KEGG: sme:SMb21176 phosphate uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter periplasmic
                     phosphonate-binding protein"
                     /protein_id="YP_001313397.1"
                     /db_xref="GI:150376801"
                     /db_xref="InterPro:IPR005770"
                     /db_xref="GeneID:5319342"
                     /translation="MFKKALLSAVALFALTGHAQAEELKEFRVGIIGGENEADRLRNY
                     QCLVDKLPAAIGVEKVSLFPAADYDGVIQGLLGGTLDYAELGASGYAKIYLAKADAVE
                     PILTTVQTDGSTGYHSIMVARKDSGITKLEDLKGKKLGFADPDSTSGYLVPLVTLPEA
                     IGAPVKEYFGETGFGGGHENLVLEVVKGTFDAGTTFGSGVGEFKDGYTSGNLRKMVDK
                     GIVDMNDLVELWKSPLIPNGPIVVRTALNGDMKAKFKQFMIDLPKTDAACFSAIQGGD
                     FTGFVEVNSEFYKPIIDARKATIGG"
     misc_feature    complement(1178514..1179413)
                     /locus_tag="Smed_4667"
                     /note="phosphonate ABC transporter, periplasmic
                     phosphonate binding protein; Region: PhnD; TIGR03431"
                     /db_xref="CDD:132472"
     sig_peptide     complement(1179348..1179413)
                     /locus_tag="Smed_4667"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.885 at
                     residue 22"
     misc_feature    complement(<1178976..>1179056)
                     /locus_tag="Smed_4667"
                     /note="TRAP transporter solute receptor, TAXI family;
                     Region: TRAP_TAXI; TIGR02122"
                     /db_xref="CDD:233736"
     gene            complement(1179501..1180403)
                     /locus_tag="Smed_4668"
                     /db_xref="GeneID:5319343"
     CDS             complement(1179501..1180403)
                     /locus_tag="Smed_4668"
                     /note="TIGRFAM: phosphonate ABC transporter, ATPase
                     subunit;
                     PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21177 phosphate uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATPase"
                     /protein_id="YP_001313398.1"
                     /db_xref="GI:150376802"
                     /db_xref="InterPro:IPR000767"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR012693"
                     /db_xref="GeneID:5319343"
                     /translation="MKRGYGRVIPINGPPEEELLPMFQLKNVTRQFGKKTAVSSVTFD
                     IPQGQMVGIIGRSGAGKSTLLRMINRLVDPSSGSIAFGEAEVSSLRGAALRKWQRDCA
                     MIFQQFNLVPRLDVLTNVLLGRLNHRSTVLSVLNMFSRDERIMAIGALERLGIEQTAL
                     QPAGTLSGGQQQRVAIARALMQQPKVLLADEPIASLDPLNAKIVMDALRDINERDGIT
                     VITNLHTLDTARNYCERIIGMAHGRVVFDGQPKDLTSAAVAQIYGGDTAIEESMTSTS
                     INIPTEAPRETASAGSKPLALAGL"
     misc_feature    complement(1179570..1180343)
                     /locus_tag="Smed_4668"
                     /note="ABC-type phosphate/phosphonate transport system,
                     ATPase component [Inorganic ion transport and metabolism];
                     Region: COG3638"
                     /db_xref="CDD:226164"
     misc_feature    complement(1179618..1180337)
                     /locus_tag="Smed_4668"
                     /note="ATP-binding cassette domain of the binding
                     protein-dependent phosphonate transport system; Region:
                     ABC_PhnC_transporter; cd03256"
                     /db_xref="CDD:213223"
     misc_feature    complement(1180218..1180241)
                     /locus_tag="Smed_4668"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213223"
     misc_feature    complement(order(1179732..1179734,1179831..1179836,
                     1180086..1180088,1180215..1180223,1180227..1180232))
                     /locus_tag="Smed_4668"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213223"
     misc_feature    complement(1180086..1180097)
                     /locus_tag="Smed_4668"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213223"
     misc_feature    complement(1179879..1179908)
                     /locus_tag="Smed_4668"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213223"
     misc_feature    complement(1179831..1179848)
                     /locus_tag="Smed_4668"
                     /note="Walker B; other site"
                     /db_xref="CDD:213223"
     misc_feature    complement(1179813..1179824)
                     /locus_tag="Smed_4668"
                     /note="D-loop; other site"
                     /db_xref="CDD:213223"
     misc_feature    complement(1179726..1179746)
                     /locus_tag="Smed_4668"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213223"
     gene            complement(1180511..1181635)
                     /locus_tag="Smed_4669"
                     /db_xref="GeneID:5319344"
     CDS             complement(1180511..1181635)
                     /locus_tag="Smed_4669"
                     /note="PFAM: FAD dependent oxidoreductase;
                     KEGG: sme:SMb21179 putative FAD-dependent
                     glycerol-3-phosphate dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD dependent oxidoreductase"
                     /protein_id="YP_001313399.1"
                     /db_xref="GI:150376803"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="GeneID:5319344"
                     /translation="MRNYDIVIIGGGIAGLSLAYFLSPHRSVAVLEREEAIGYHSTGR
                     SAAEFVLRYNAAEICQLATISKGFFDRPPEGFSDVPLLRQRGGVMIASAEKLQRFEKL
                     LAEERAFTPEIERLTKDEAIARVPILKAEYVAAAFYDPNFWDIEVENLLQGYVKGARR
                     NGCEILERQEILGAQHDGPAWLLRTAGGEIGAKIVVNAAGAWADPIATLFRVKPAGIV
                     PHRRTAITVDLPAGVDAANLPEINEIDEDFYMKPEGGRLLASPADATPCEASDVQPEE
                     IDVAWAAHYVEEATTIKVQRIAKSWAGLRSFSPDRLPVIGFGAERPDFFWLAGQGGYG
                     ILTSPALGALAASLLTDTAPPEGFRADGLDSSVFDPRRFR"
     misc_feature    complement(1180631..1181635)
                     /locus_tag="Smed_4669"
                     /note="Glycine/D-amino acid oxidases (deaminating) [Amino
                     acid transport and metabolism]; Region: DadA; COG0665"
                     /db_xref="CDD:223737"
     misc_feature    complement(<1180973..1181626)
                     /locus_tag="Smed_4669"
                     /note="hydroxyglutarate oxidase; Provisional; Region:
                     PRK11728"
                     /db_xref="CDD:183292"
     gene            complement(1181714..1182667)
                     /locus_tag="Smed_4670"
                     /db_xref="GeneID:5318127"
     CDS             complement(1181714..1182667)
                     /locus_tag="Smed_4670"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb21180 putative transcriptional regulator,
                     LysR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001313400.1"
                     /db_xref="GI:150376804"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318127"
                     /translation="MTSNRLERFAHNLDWNLLRTFVVVVEEGSITAAANRLLLQQPAV
                     SMALKRLEQTIGQKLIDRRPGRFDLTEAGEKLHLQCRDIFAAVIRLPHVLETAGEEIT
                     GHLNIHAVSHAHNPAWDRKLSSFFRMHPKVTISITVATTVDVLSAVERNIATLGLCDG
                     IIPDGLSKSFHIRERYALYCGRGHRLFGADDVDFHDLRGDPYVAFIADVLGGQHMNSV
                     TAVRAVGSFGQQVRGVSCNVEEVLRLIAANVGIGMLPDHIARPSVATGELWQLPPYRD
                     LPTTDVFRISNPNSILNPAEAAFLAHVADTEALDHCGHQQD"
     misc_feature    complement(1181753..1182631)
                     /locus_tag="Smed_4670"
                     /note="Transcriptional regulator [Transcription]; Region:
                     LysR; COG0583"
                     /db_xref="CDD:223656"
     misc_feature    complement(1182446..1182625)
                     /locus_tag="Smed_4670"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    complement(1181759..1182304)
                     /locus_tag="Smed_4670"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cd05466"
                     /db_xref="CDD:176102"
     misc_feature    complement(order(1181927..1181932,1181936..1181941,
                     1181957..1181974,1182254..1182274,1182278..1182280,
                     1182290..1182292,1182299..1182304))
                     /locus_tag="Smed_4670"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            1182856..1184043
                     /locus_tag="Smed_4671"
                     /db_xref="GeneID:5318128"
     CDS             1182856..1184043
                     /locus_tag="Smed_4671"
                     /note="PFAM: acyl-CoA dehydrogenase domain protein;
                     Acyl-CoA dehydrogenase type 2 domain;
                     KEGG: sme:SMb21181 putative glutaryl-CoA dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase domain-containing
                     protein"
                     /protein_id="YP_001313401.1"
                     /db_xref="GI:150376805"
                     /db_xref="InterPro:IPR006089"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR006092"
                     /db_xref="InterPro:IPR013107"
                     /db_xref="GeneID:5318128"
                     /translation="MAGKSQFQWDDPFLLEDQLTEDERMIRDTARAYAQEKLQPRVIE
                     AYREETTDPAIFREMGDLGLLGVTVPDSYGGVGASYVAYGLVAREVERVDSGYRSMMS
                     VQSSLVVYPIYAYGSEDQKRKYLPKLISGEWIGCFGLTEPDAGSDPAGMKTRAIRTEG
                     GYRLIGSKMWISNAPLADVFVVWAKSEAHDNAIRGFVLEKGTKGLSAPKIAGKLSLRA
                     SITGEIVLDNVEVGEEALLPDVEGLKGPFGCLNRARYGISWGALGAAEFCWHAARQYG
                     LDRKQFNRPLAQTQLFQKKLADMQTEIALGLQGSLRVGRLMDEGRMAPEMISIVKRNN
                     CGKALDIARQARDMHGGNGISEEYQVMRHMLNLETVNTYEGTHDVHALILGRAQTGLQ
                     AFF"
     misc_feature    1182874..1184037
                     /locus_tag="Smed_4671"
                     /note="Glutaryl-CoA dehydrogenase; Region: GCD; cd01151"
                     /db_xref="CDD:173840"
     misc_feature    1182904..1184040
                     /locus_tag="Smed_4671"
                     /note="Acyl-CoA dehydrogenases [Lipid metabolism]; Region:
                     CaiA; COG1960"
                     /db_xref="CDD:224871"
     misc_feature    order(1183264..1183266,1183270..1183275,1183288..1183293,
                     1183363..1183365,1183369..1183371,1183960..1183962,
                     1183981..1183983,1183987..1183989)
                     /locus_tag="Smed_4671"
                     /note="FAD binding site [chemical binding]; other site"
                     /db_xref="CDD:173840"
     misc_feature    order(1183291..1183293,1183582..1183584,1183603..1183608,
                     1183615..1183617,1183972..1183977)
                     /locus_tag="Smed_4671"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173840"
     misc_feature    1183975..1183977
                     /locus_tag="Smed_4671"
                     /note="catalytic base [active]"
                     /db_xref="CDD:173840"
     gene            1184052..1185233
                     /locus_tag="Smed_4672"
                     /db_xref="GeneID:5318129"
     CDS             1184052..1185233
                     /locus_tag="Smed_4672"
                     /note="PFAM: L-carnitine dehydratase/bile acid-inducible
                     protein F;
                     KEGG: sme:SMb21182 putative conserved membrane-anchored
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine dehydratase/bile acid-inducible
                     protein F"
                     /protein_id="YP_001313402.1"
                     /db_xref="GI:150376806"
                     /db_xref="InterPro:IPR003673"
                     /db_xref="GeneID:5318129"
                     /translation="MEAPLKGIRVLELARILAGPWIGQTLADLGADVIKVESPAGDDT
                     RSWGPPFVQGEGGERLDAAYFHACNRGKRSVVLDFTTEEGQEAVRRLASQSDVLLENF
                     KVGGLAKYGLDYESLRKVNPRLIYCSVTGFGQEGPYAHRAGYDYIVQGMSGIMDLTGE
                     PDGEPQKIGVAFADIFTGLYGVIAVQAALAQRERNGAGQHIDMALLDCMTGVLANQAL
                     NFLVSGKAPRRLGNAHPNIAPYQVFPTSDGHLIVAVGNDRQFVKFCELLGRPDLASDP
                     RYRTNADRVQNRDSLTPELAAETAKFERDTLLARLEASGVPGGPINTVADVFADPQII
                     HRQMRVETPHTGAATGTSPGIRTPIRFSDAALALERGVPRLGEHTEEVLAEIGMSLLE
                     P"
     misc_feature    1184052..1185227
                     /locus_tag="Smed_4672"
                     /note="Predicted acyl-CoA transferases/carnitine
                     dehydratase [Energy production and conversion]; Region:
                     CaiB; COG1804"
                     /db_xref="CDD:224717"
     misc_feature    1184274..1184807
                     /locus_tag="Smed_4672"
                     /note="CoA-transferase family III; Region: CoA_transf_3;
                     pfam02515"
                     /db_xref="CDD:217078"
     gene            complement(1185403..1187298)
                     /locus_tag="Smed_4673"
                     /db_xref="GeneID:5318130"
     CDS             complement(1185403..1187298)
                     /locus_tag="Smed_4673"
                     /note="molecular chaperone"
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein 90"
                     /protein_id="YP_001313403.1"
                     /db_xref="GI:150376807"
                     /db_xref="InterPro:IPR001404"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="GeneID:5318130"
                     /translation="MSEVETSVEKHVFEADVAKLLHLMVHSVYSDKNVFLRELISNAA
                     DACEKLRYEAIVAPELLGSDPTSRITLTLDEENARLTIEDNGIGMGRDELVESLGTIA
                     RSGTRAFMERIEAAQNKDGAQLIGQFGVGFYSAFMVADNVDVVSRRAGTDKAWLWASD
                     GKGSYTVSAFDLADAPARGTRITLHLMEDAKTFTSRWTVEGIVKEQSGHVPVPISIVE
                     KPGAEPVQVVDGTALWTKQKSEITTEDYTDFYRGVAGQYDEPALTVHFRAEGRHEYTA
                     LAFVPGSKPFDLFDPDRKGRMKLYVKRVFITDEAELLPRYLRFVRGLVDTADLPLNVS
                     REMIQESPLLANIRKGVTNRVLTSIEKLAESDPEAFAKLWENFGSVIKEGIYEDFERR
                     AQLLALSRFRTTVDDEKPRSLSDYVKEMKEGQTAIYYLTGDNLAQLKASPQLEGFRAR
                     GIEVLLLTCPVDSFWVTTAPDFEGKPFKSITQGAADLAGIAKKNDAAAAASAEAGVAV
                     TDFLAFAKETLGDAVSDVRTSDRLTESAVCLVATEQGPDLQLQKMLQGAGRIESAAKP
                     VLEVNPGHQLITALAGCPGEDKTFREDAVKLLFDQARVLDGDKPEDPRAFAERLTRVF
                     SRALKGS"
     misc_feature    complement(1185412..1187283)
                     /locus_tag="Smed_4673"
                     /note="heat shock protein 90; Provisional; Region:
                     PRK05218"
                     /db_xref="CDD:235366"
     misc_feature    complement(1186849..1187196)
                     /locus_tag="Smed_4673"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(1186861..1186863,1186867..1186869,
                     1186903..1186914,1187032..1187037,1187041..1187043,
                     1187047..1187049,1187053..1187055,1187164..1187166,
                     1187173..1187175,1187185..1187187))
                     /locus_tag="Smed_4673"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(1187173..1187175)
                     /locus_tag="Smed_4673"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(1186906..1186908,1186912..1186914,
                     1187035..1187037,1187041..1187043))
                     /locus_tag="Smed_4673"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            1187462..1188418
                     /locus_tag="Smed_4674"
                     /db_xref="GeneID:5318131"
     CDS             1187462..1188418
                     /locus_tag="Smed_4674"
                     /EC_number="2.3.1.8"
                     /note="catalyzes the formation of acetyl phosphate from
                     acetyl-CoA and phosphate; can also act with other
                     short-chain acyl-CoAs"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="YP_001313404.1"
                     /db_xref="GI:150376808"
                     /db_xref="InterPro:IPR002505"
                     /db_xref="GeneID:5318131"
                     /translation="MVSEVMELAAEPSKYDRLIAAAQAEEPAVTLVVHPCDETALRGA
                     LEAAQMRLITPVLVGPRVRIRSIAAEHRLDLGQWEIVDVPHSHAAAAKAVALIREGKG
                     SLLMKGSLHTDELMREVAAAASGLRTERRISHVFVMDVPGHADTLFITDAAINIAPDL
                     DAKRDIVQNAIDLWVTIGLGEPRVAILSAVETVTMKIPSTIEAAALCKMAERGQITGG
                     LLDGPLAFDNAIDPEAARIKGIVSPVAGRAQILVVPDLEAGNMLAKNLTFLAHADAAG
                     IVLGARVPIVLTSRADSVRTRLASCAVASLFAARRRAAQVAV"
     misc_feature    1187477..1188382
                     /locus_tag="Smed_4674"
                     /note="phosphate acetyltransferase; Provisional; Region:
                     PRK11890"
                     /db_xref="CDD:183361"
     misc_feature    <1187504..1188382
                     /locus_tag="Smed_4674"
                     /note="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase; Validated; Region: PRK08190"
                     /db_xref="CDD:236180"
     gene            1188420..1189595
                     /locus_tag="Smed_4675"
                     /db_xref="GeneID:5318132"
     CDS             1188420..1189595
                     /locus_tag="Smed_4675"
                     /EC_number="2.7.2.1"
                     /note="AckA utilizes acetate and can acetylate CheY which
                     increases signal strength during flagellar rotation;
                     utilizes magnesium and ATP; also involved in conversion of
                     acetate to aceyl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="YP_001313405.1"
                     /db_xref="GI:150376809"
                     /db_xref="InterPro:IPR000890"
                     /db_xref="InterPro:IPR004372"
                     /db_xref="GeneID:5318132"
                     /translation="MEAVLVVNAGSSSLKFQIFGIAGGGLQRQVRGKIDGIGTHPHLK
                     ASNADGTDLVDRALDSSTVRDLPTAIAEARNWLGGVDGIELRAIGHRVVHGGPDYVRP
                     VLIDAAVLERLASYQHLAPLHQPNNLAPIRLAMDINPDVPQVACFDTAFHRGRAEHTD
                     CYALPHAFYEDGIRRYGFHGLSYEYIAERLREVAPDIAGGRVIVAHLGSGVSMCALKD
                     GRSVETTMGFTALDGLPMGTRPGQLDPGVILYLLTHHGMSAQEISDLLYHDAGLKGLS
                     GISNDMRELSASEDPRASFAIDHFVHRCSLHAGMLAAALGGLDAFVFTAGIGENSATV
                     RARIAERLDWLGAELDAKANDTGAPVVSRAGSRVSLHVIPTDEELMIARHTLALLRV"
     misc_feature    1188429..1189592
                     /locus_tag="Smed_4675"
                     /note="propionate/acetate kinase; Provisional; Region:
                     PRK12379"
                     /db_xref="CDD:183484"
     misc_feature    1188429..1189589
                     /locus_tag="Smed_4675"
                     /note="acetate kinase A/propionate kinase 2; Reviewed;
                     Region: PRK00180"
                     /db_xref="CDD:234680"
     gene            complement(1189623..1191098)
                     /locus_tag="Smed_4676"
                     /db_xref="GeneID:5318133"
     CDS             complement(1189623..1191098)
                     /locus_tag="Smed_4676"
                     /note="TIGRFAM: succinic semialdehyde dehydrogenase;
                     PFAM: aldehyde dehydrogenase;
                     KEGG: sme:SMb21185 putative succinate-semialdehyde
                     dehydrogenase (NAD(P)+) protein"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="YP_001313406.1"
                     /db_xref="GI:150376810"
                     /db_xref="InterPro:IPR002086"
                     /db_xref="InterPro:IPR010102"
                     /db_xref="GeneID:5318133"
                     /translation="MALTPALTGHIREPKLFASLDSVALPAGEWAGPTFDVFNPSTGE
                     LLAKLPDMGIKEARAAIDAAALAQPLWAGKPAKDRSIVLRRWHDLIVEHVDDLAAILT
                     AEMGKPVGEAKGEVLHAASYIEWYAEEAKRVYGETFPAPANDRRMLVIKQPVGVVGTI
                     TPWNFPASMVARKISPALAAGCTIVLKPAEQTPLVAGAMFALAEQAGFPEGVLNLLYA
                     SEGAPIGRELCSNPRIRKISFTGSTEVGRLLMRQCSDQIKKVSLELGGNAPFIVFDDA
                     DIDEAVDGALQAKFRNAGQTCVSANRIYVQTAVHDAFAEKFVTRVRELTVGDGFAPGV
                     TIGPMIDAHAIEKIEAHVSDAIAKGAEVRCGGNRIGTAGTFFEPTVLTGISHDMRVAQ
                     EETFGPIAPIIRFDSAEQVVAEANDTIYGLAAYFYAENLKRVWHVAEALEYGMVGINT
                     GRMSSEAAPFGGIKQSGIGREGSRHGLEDYLEMKYLCMGNI"
     misc_feature    complement(1189626..1191026)
                     /locus_tag="Smed_4676"
                     /note="succinic semialdehyde dehydrogenase; Region:
                     PLN02278"
                     /db_xref="CDD:215157"
     misc_feature    complement(1189635..1190990)
                     /locus_tag="Smed_4676"
                     /note="Mitochondrial succinate-semialdehyde dehydrogenase
                     and ALDH family members 5A1 and 5F1-like; Region:
                     ALDH_F5_SSADH_GabD; cd07103"
                     /db_xref="CDD:143421"
     misc_feature    complement(order(1189635..1189655,1189689..1189691,
                     1189704..1189706,1189722..1189727,1189734..1189736,
                     1189752..1189772,1189776..1189778,1189785..1189787,
                     1189791..1189793,1189803..1189808,1189812..1189814,
                     1190016..1190018,1190154..1190156,1190166..1190168,
                     1190337..1190339,1190346..1190348,1190358..1190360,
                     1190394..1190396,1190643..1190645,1190658..1190666,
                     1190682..1190708,1190712..1190717,1190724..1190726,
                     1190847..1190849,1190874..1190876))
                     /locus_tag="Smed_4676"
                     /note="tetramerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:143421"
     misc_feature    complement(order(1189719..1189721,1189833..1189835,
                     1189911..1189913,1189917..1189919,1190208..1190210,
                     1190304..1190312,1190352..1190357,1190364..1190366,
                     1190373..1190384,1190529..1190534,1190538..1190540,
                     1190583..1190585,1190607..1190621))
                     /locus_tag="Smed_4676"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:143421"
     misc_feature    complement(order(1190208..1190210,1190217..1190219,
                     1190310..1190312,1190607..1190609))
                     /locus_tag="Smed_4676"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143421"
     gene            complement(1191216..1192484)
                     /locus_tag="Smed_4677"
                     /db_xref="GeneID:5318134"
     CDS             complement(1191216..1192484)
                     /locus_tag="Smed_4677"
                     /EC_number="2.6.1.19"
                     /note="catalyzes the formation of succinate semialdehyde
                     and glutamate from 4-aminobutanoate and 2-oxoglutarate"
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate aminotransferase"
                     /protein_id="YP_001313407.1"
                     /db_xref="GI:150376811"
                     /db_xref="InterPro:IPR004632"
                     /db_xref="InterPro:IPR005814"
                     /db_xref="GeneID:5318134"
                     /translation="MTSLTDRKNAAISRGVGMTTQIYAERAENAEIWDKEGNRYIDFA
                     SGIAVVNTGHRHPKVIAAVKAQLDRFTHTCHQVVPYENYVHLAERLNAIVPGDFAKKT
                     IFVTTGAEAVENAVKIARAATGRQAIVAFGGGFHGRTFMGMALTGKVVPYKVGFGAMP
                     ADVFHAPFPVELHGVSVEQSLAALKKLFAADVDPNRVAAIIIEPVQGEGGFYPVPTAF
                     MKALREICDQNGILLIADEVQTGFARTGKLLAMEHHGVAPDLTTMAKSLAGGFPLAAV
                     TGRAEIMDAPGPGGLGGTYGGNPLGIAAAHAVLDVIAEENLCERANQLGNRLKQRLAA
                     IREKAPEIVDIRGPGFMNAVEFNDVKTNVPSAEFANKVRLLALEKGLILLTCGVHGNV
                     IRFLAPITIQDDVFAEALDILESSILEARG"
     misc_feature    complement(1191219..1192484)
                     /locus_tag="Smed_4677"
                     /note="4-aminobutyrate aminotransferase; Provisional;
                     Region: PRK07495"
                     /db_xref="CDD:236032"
     misc_feature    complement(1191234..1192421)
                     /locus_tag="Smed_4677"
                     /note="Acetyl ornithine aminotransferase family. This
                     family belongs to pyridoxal phosphate (PLP)-dependent
                     aspartate aminotransferase superfamily (fold I). The major
                     groups in this CD correspond to ornithine
                     aminotransferase, acetylornithine aminotransferase;
                     Region: OAT_like; cd00610"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(1191690..1191692,1191768..1191773,
                     1191777..1191779,1191876..1191878,1192071..1192073,
                     1192077..1192082,1192158..1192166))
                     /locus_tag="Smed_4677"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(1191690..1191692,1191768..1191770,
                     1191777..1191779,1191876..1191878,1192077..1192082,
                     1192158..1192163))
                     /locus_tag="Smed_4677"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99735"
     misc_feature    complement(1191690..1191692)
                     /locus_tag="Smed_4677"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     gene            1192719..1193549
                     /locus_tag="Smed_4678"
                     /db_xref="GeneID:5318135"
     CDS             1192719..1193549
                     /locus_tag="Smed_4678"
                     /note="PFAM: regulatory protein MerR; Cupin 2 conserved
                     barrel domain protein;
                     SMART: helix-turn-helix domain protein;
                     KEGG: sme:SMb21187 putative protein, similar to
                     transcriptional regulators MerR and LacI family"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="YP_001313408.1"
                     /db_xref="GI:150376812"
                     /db_xref="InterPro:IPR000551"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="GeneID:5318135"
                     /translation="MGGVGAIRYKVAEAARLAGVSASTLRLWETQGLVVPERSATGHR
                     QYTDADLARLKRISWFRSERGLNPAAIREALEAENAAADDENGLAVLSDENAELQVGR
                     KLRSLRHTAGKTLEQVAGDIGIAASVLSTLERTSQGVSVAVLHNLAEYFDTTVSSLSG
                     EEETKARALVRAGEWRNWPRTTPGVTVQLLAEGKNQMDCHRFVLAPGASSEGAYRHEG
                     EEFVYVLSGRVEFVLDSDQFYDLHPGDSLYFESRRRHAWSNRHDGETVLLWINTPPTF
                     "
     misc_feature    1192743..>1192919
                     /locus_tag="Smed_4678"
                     /note="Helix-Turn-Helix DNA binding domain of MerR-like
                     transcription regulators; Region: HTH_MerR-like; cd00592"
                     /db_xref="CDD:133378"
     misc_feature    1192743..1192919
                     /locus_tag="Smed_4678"
                     /note="MerR HTH family regulatory protein; Region: MerR_1;
                     pfam13411"
                     /db_xref="CDD:205589"
     misc_feature    order(1192746..1192754,1192794..1192796,1192842..1192850)
                     /locus_tag="Smed_4678"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:133378"
     misc_feature    1193001..1193546
                     /locus_tag="Smed_4678"
                     /note="DNA-binding transcriptional repressor PuuR;
                     Provisional; Region: PRK09943"
                     /db_xref="CDD:182158"
     misc_feature    1193019..1193192
                     /locus_tag="Smed_4678"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; Region: HTH_XRE; cd00093"
                     /db_xref="CDD:238045"
     misc_feature    order(1193031..1193033,1193043..1193045,1193118..1193120)
                     /locus_tag="Smed_4678"
                     /note="non-specific DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238045"
     misc_feature    order(1193040..1193042,1193115..1193117)
                     /locus_tag="Smed_4678"
                     /note="salt bridge; other site"
                     /db_xref="CDD:238045"
     misc_feature    order(1193061..1193066,1193097..1193099,1193106..1193108,
                     1193118..1193123)
                     /locus_tag="Smed_4678"
                     /note="sequence-specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238045"
     misc_feature    1193316..1193528
                     /locus_tag="Smed_4678"
                     /note="Cupin domain; Region: Cupin_2; pfam07883"
                     /db_xref="CDD:219618"
     gene            1193844..1194977
                     /locus_tag="Smed_4679"
                     /db_xref="GeneID:5318136"
     CDS             1193844..1194977
                     /locus_tag="Smed_4679"
                     /note="PFAM: acyltransferase 3;
                     KEGG: sme:SMb21188 putative acyltransferase, possibly
                     surface-saccharide specific acetyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase 3"
                     /protein_id="YP_001313409.1"
                     /db_xref="GI:150376813"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="GeneID:5318136"
                     /translation="MQVVRDQQLDGLRAVAVTMVLYAHFFAADGSHWGHLGVRLFFVL
                     SGFLITRLLLDARDAARFEPSTALKSFYARRALRIFPPYFAVLAAVFLLDLERSKQVM
                     AWHGLYLSNFWYALQNEWSPWVLCHTWSLSIEEQFYLIWPLVVLLLPRRSIAGVCIGV
                     IVCSLVYRFYWPFTGTPSLARDLLPPASMDALAVGALLAARPSWRAAWPRWAELSWIP
                     LSIASFALVWLKPVPMTPVIAWLAWIGLEVVPLLPLAMLVGSCSKGIGGIAGRVVALS
                     PVAALGRISYGVYLFHAVVLAVVVQAQPFIPVNVTDQGVGRFVVAGALTLMLASASWI
                     LFEKPLNGLKRHFPYVRPEGAAGPVTAVPRVRPDEALQTPPLR"
     misc_feature    1193856..1194896
                     /locus_tag="Smed_4679"
                     /note="Predicted acyltransferases [Lipid metabolism];
                     Region: COG1835"
                     /db_xref="CDD:224748"
     gene            1194993..1196096
                     /locus_tag="Smed_4680"
                     /db_xref="GeneID:5318137"
     CDS             1194993..1196096
                     /locus_tag="Smed_4680"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb21189 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313410.1"
                     /db_xref="GI:150376814"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318137"
                     /translation="MPLPLVSVLLPVYNGEPYIAAALESVLRQDYQRVEVIAIDDGST
                     DRSRDILERYGKTDSRLSIISRENRGLVASLNEGLALAKGELIARMDADDIAYPSRLS
                     RQVALFGEEPRLALCGTGIDMLIGNRIIRGRPNPIYRPGSLRTLSMFFTIFMHSTVVY
                     NRTIIPDEMLRYDSNYVHAEDFDLFRRIADRFPVHMIDEPLVAYRIHEDSVTSKHKRQ
                     MRRTHLSIVAENLARDALLDDSAALEALGAAVTGETVARLADCVLALERAIAARPVEV
                     RGAYEDGALCFFYFLYQLIADEEQPRLTHEFLTRTGKWGLIRRRERYGLLAATRAPWC
                     SRISLAASRRVDRLARHLQSVPAATVLPEHGLT"
     misc_feature    1195029..>1195655
                     /locus_tag="Smed_4680"
                     /note="Glycosyltransferases involved in cell wall
                     biogenesis [Cell envelope biogenesis, outer membrane];
                     Region: WcaA; COG0463"
                     /db_xref="CDD:223539"
     misc_feature    1195029..1195631
                     /locus_tag="Smed_4680"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cl11394"
                     /db_xref="CDD:245596"
     misc_feature    order(1195029..1195031,1195107..1195109,1195263..1195265,
                     1195269..1195271)
                     /locus_tag="Smed_4680"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            1196098..1197135
                     /locus_tag="Smed_4681"
                     /db_xref="GeneID:5319323"
     CDS             1196098..1197135
                     /locus_tag="Smed_4681"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb21190 putative glycosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313411.1"
                     /db_xref="GI:150376815"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5319323"
                     /translation="MAPEPLAMMQDDPIAPDARRLVAASPSGEPGPFASFIVCTHNRV
                     HALAASIRSIETASRAHAMVESELVVVDNGSTDGTAEELAGIAARTMMSITLLTEPRP
                     GLAAARNTGMARARGRILIFIDDDCEVDSNYLRDLERHYSGGDEQVIRGGRVELGNPA
                     DLPFTVKRSKVAARLTRDVHPGGFVLGCNMTMHRDIAARIGPFDERFGAGAPLKAAED
                     TDYLVRAFELGIPVEYVPDMVVHHHHGRRHRAAIEELHRNYSLGNGGLCLKHLLRAPW
                     LLKHFGWTVRSAWGEAFGRSRFDPELQLSHWPIVSMNLLGALRFAWLAAANAEPRIER
                     RRVEQPEPKLR"
     misc_feature    1196200..1196868
                     /locus_tag="Smed_4681"
                     /note="Glycosyltransferase like family 2; Region:
                     Glyco_tranf_2_3; pfam13641"
                     /db_xref="CDD:222281"
     misc_feature    1196200..1196700
                     /locus_tag="Smed_4681"
                     /note="Glycosyl transferase family 2; Region:
                     Glycos_transf_2; pfam00535"
                     /db_xref="CDD:215980"
     misc_feature    order(1196212..1196214,1196218..1196220,1196308..1196310,
                     1196467..1196469,1196473..1196475)
                     /locus_tag="Smed_4681"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            1197145..1198938
                     /locus_tag="Smed_4682"
                     /db_xref="GeneID:5319324"
     CDS             1197145..1198938
                     /locus_tag="Smed_4682"
                     /note="PFAM: ABC transporter transmembrane region; ABC
                     transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21191 putative surface saccharide exporting
                     ABC transporter protein, consisting of ATP-binding and
                     membrane-spanning domains"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313412.1"
                     /db_xref="GI:150376816"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="GeneID:5319324"
                     /translation="MRRFLLPGLEVLRGALGRQMRLLPAVVILGLTSAALEGAGIGLI
                     IPMLSIIAGDEQATGLSGISAYFQGMGEGLDDGERLLAISVAVLALILLKNVLSFANT
                     LLTTFIYGKASHSVRSALSDQLLRIGYPFFMQHNPGRLLNIISNESWRASDAIQTVLA
                     AIVHGSAALILLAFLLLMSWQMTLFVALGLVLVQLAHAALSATLKGPSRHVTSFNSEL
                     SARMLHLVHAGRLIRVFGQEPREKQAFDSASDAVRRAGFVLQSRQGALPPLTEVLHSA
                     LFLAVVVSAWSVGVSFPVIVAFVVLLYRLQPHVRALQMSWSQIQGWSGSLEEVRWLLD
                     SSDKPKPPEGKTPVDGLHEILVFDRVTFRYPGSEVRPVVLRSASFEIRSGRSTAIIGR
                     SGAGKTTIVNLLCRFVEPDEGCILVDGVPLSEIDPIQWRRQIAVASQDLELVDGSILE
                     NITYGQSATFAEAERAAKLAEAHGFIEQLPQGYQTVVGYRGASLSAGQRQRIALARAL
                     VRDPAILILDEATNAVDGLSEAAIVETLRLRAGRRTTIVISHHRSTISFCDDLVVLGS
                     GHVKGQAALADVASLSMDQLYEHETRADSAT"
     misc_feature    1197265..1198845
                     /locus_tag="Smed_4682"
                     /note="lipid A export permease/ATP-binding protein MsbA;
                     Region: MsbA_lipidA; TIGR02203"
                     /db_xref="CDD:131258"
     misc_feature    1197430..1197978
                     /locus_tag="Smed_4682"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:216049"
     misc_feature    1198210..1198851
                     /locus_tag="Smed_4682"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    1198315..1198338
                     /locus_tag="Smed_4682"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(1198324..1198329,1198333..1198341,1198459..1198461,
                     1198696..1198701,1198792..1198794)
                     /locus_tag="Smed_4682"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    1198450..1198461
                     /locus_tag="Smed_4682"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    1198624..1198653
                     /locus_tag="Smed_4682"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    1198684..1198701
                     /locus_tag="Smed_4682"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    1198708..1198719
                     /locus_tag="Smed_4682"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    1198780..1198800
                     /locus_tag="Smed_4682"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            complement(1199003..1200046)
                     /locus_tag="Smed_4683"
                     /db_xref="GeneID:5319325"
     CDS             complement(1199003..1200046)
                     /locus_tag="Smed_4683"
                     /EC_number="4.1.2.13"
                     /note="class II aldolase; catalyzes the reversible aldol
                     condensation of dihydroxyacetonephosphate and
                     glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis
                     and gluconeogenesis"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphate aldolase"
                     /protein_id="YP_001313413.1"
                     /db_xref="GI:150376817"
                     /db_xref="InterPro:IPR000771"
                     /db_xref="InterPro:IPR006412"
                     /db_xref="GeneID:5319325"
                     /translation="MALITLRQLLDHAAENNYALPAFNVNNLEYIQAVMRAADATDSP
                     VILQASRGARAYAGDAFLRHLILGAVEEYPHIPVCLHLDHGDQPSTCISAIINGFTSV
                     MMDGSLEKDGKTVASYEYNVAVTAEVVKIAHAAGVSVEGELGCLGNLETGAGDKEDGH
                     GFEGKLSREELLTDPEQALDFVSKTGVDALAVAIGTSHGAYKFTREPDGEILSIETIA
                     KINKRLPNTHLVMHGSSSVPAVLQELFNAYGGKMKKTWGVPVSEIQKAIPLGVRKVNI
                     DTDLRLAFTGEIRKNHIEHPDNFDPRNYLKPAIAHMAEVCKERFEAFRSAGQASKIRV
                     LRLPEMAKRYAAA"
     misc_feature    complement(1199066..1200046)
                     /locus_tag="Smed_4683"
                     /note="fructose-bisphosphate aldolase; Provisional;
                     Region: PRK09197"
                     /db_xref="CDD:236406"
     misc_feature    complement(1199066..1200031)
                     /locus_tag="Smed_4683"
                     /note="Tagatose-1,6-bisphosphate (TBP) aldolase and
                     related Type B Class II aldolases. TBP aldolase is a
                     tetrameric class II aldolase that catalyzes the reversible
                     condensation of dihydroxyacetone phosphate with
                     glyceraldehyde 3-phsophate to produce tagatose 1; Region:
                     TBP_aldolase_IIB; cd00947"
                     /db_xref="CDD:238477"
     misc_feature    complement(order(1199171..1199173,1199180..1199182,
                     1199192..1199194,1199201..1199206,1199210..1199215,
                     1199576..1199578,1199840..1199845,1199852..1199854,
                     1199864..1199866,1199876..1199884,1199891..1199893,
                     1199951..1199953,1199960..1199968))
                     /locus_tag="Smed_4683"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238477"
     misc_feature    complement(order(1199213..1199218,1199222..1199224,
                     1199342..1199344,1199348..1199353,1199444..1199446,
                     1199450..1199458,1199795..1199800))
                     /locus_tag="Smed_4683"
                     /note="active site"
                     /db_xref="CDD:238477"
     misc_feature    complement(order(1199351..1199353,1199453..1199455,
                     1199795..1199797))
                     /locus_tag="Smed_4683"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:238477"
     misc_feature    complement(order(1199342..1199344,1199348..1199350,
                     1199444..1199446,1199450..1199452,1199456..1199458))
                     /locus_tag="Smed_4683"
                     /note="Na+ binding site [ion binding]; other site"
                     /db_xref="CDD:238477"
     gene            1200489..1200725
                     /locus_tag="Smed_4684"
                     /db_xref="GeneID:5319326"
     CDS             1200489..1200725
                     /locus_tag="Smed_4684"
                     /note="KEGG: sme:SMb21195 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313414.1"
                     /db_xref="GI:150376818"
                     /db_xref="GeneID:5319326"
                     /translation="MQSDIRLSAPRGAHAPTRSGNSLQMLCNLGVYRCSSFKEKDAIF
                     RTDQLAFAENLHFSPSINEPKNEGKEKKNGFTQT"
     gene            1200706..1202304
                     /locus_tag="Smed_4685"
                     /db_xref="GeneID:5319327"
     CDS             1200706..1202304
                     /locus_tag="Smed_4685"
                     /note="PFAM: extracellular solute-binding protein family
                     5;
                     KEGG: sme:SMb21196 putative oligopeptide uptake ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313415.1"
                     /db_xref="GI:150376819"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="GeneID:5319327"
                     /translation="MALLRHNLAGAALICSLLMGASPALAQAVLHRGNAGEPQTLDQA
                     HTSINIEEFILKDLYEGLTIYDAAGKIVPGAAETWELSDDGTVYTFKLRADAKWSDGS
                     PVTAEDFAFSLRRVEDPKTAAEYANILFPIKNAEKVNKGELPVDQLGVKAVDEKTLEV
                     TLERPTPFFLELLAHQTALPVSKANVEKNGADFVKPGVMVSNGAFKLASHVPNDSLTV
                     EKNTNYWDAANVKLDKVIFYPIDDQAASVRRFEAKEMDLAYNFSADQIDRLRKSYGEQ
                     VHVSPTLATYYYAFDTRQEPYNDVRVRRALSMAVDRDFLAKEIYSGSQLPSYSMVPPG
                     IESYGDPAKADFGDMSQLDREDKAIELMKEAGYGEGGKPLNIEIRYNTNPNHERVATA
                     VADMWKNTFGAKVSLVNLDVSSHYAYLQEGGKFNVARAGWVADYADAENFLALSLSTN
                     KTFNYGHFENAEFDALMKKSYEEQDPAARSKILHEAETLLMKEQPIAPLLTQADLWLV
                     SERVQGWVDNAPNAHLSKFLSIAE"
     misc_feature    1200706..1202301
                     /locus_tag="Smed_4685"
                     /note="ABC-type oligopeptide transport system, periplasmic
                     component [Amino acid transport and metabolism]; Region:
                     OppA; COG4166"
                     /db_xref="CDD:226636"
     sig_peptide     1200706..1200786
                     /locus_tag="Smed_4685"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 27"
     misc_feature    1200790..1202289
                     /locus_tag="Smed_4685"
                     /note="The substrate-binding component of an ABC-type
                     oligopetide import system contains the type 2 periplasmic
                     binding fold; Region: PBP2_OppA; cd08504"
                     /db_xref="CDD:173869"
     misc_feature    order(1200859..1200861,1201480..1201482,1201549..1201551,
                     1201939..1201941,1201990..1201992,1201996..1202010,
                     1202209..1202211)
                     /locus_tag="Smed_4685"
                     /note="peptide binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:173869"
     gene            1202356..1203279
                     /locus_tag="Smed_4686"
                     /db_xref="GeneID:5319328"
     CDS             1202356..1203279
                     /locus_tag="Smed_4686"
                     /EC_number="3.1.3.1"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21197 putative oligopeptide uptake ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="YP_001313416.1"
                     /db_xref="GI:150376820"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319328"
                     /translation="MISFILRRLASAVPTLFIVVTISFFLMRFAPGGPFNLERPLPPS
                     TMENLMRTYHLDQPLWRQYVHYLSNAVTGDFGPSYIYHDNNVAQLIGKGLPYSMELGF
                     YALLLAVVGGVITGTIAALKQNSFLDFAVMSVSTIGVTVPNFVVGPVLTLIFAIMLAW
                     LPAGGWGDGSLRFLILPMIALALPQLAVFARLTRGSMIEALHTDHIRTAKAYGLPSRA
                     VVVTHAMRGAMLPVVSYLAPCAAALLTGSAVVETIFTIPGVGRYFVLGAINRDYTLVM
                     GTVILIAIFVILFNLLVDILYGLLDPRVRHD"
     misc_feature    1202356..1203273
                     /locus_tag="Smed_4686"
                     /note="oligopeptide transporter permease; Reviewed;
                     Region: oppB; PRK09471"
                     /db_xref="CDD:181886"
     misc_feature    1202635..1203219
                     /locus_tag="Smed_4686"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1202683..1202688,1202695..1202700,1202713..1202715,
                     1202746..1202757,1202761..1202790,1202797..1202802,
                     1202806..1202808,1202905..1202910,1202914..1202916,
                     1202920..1202922,1202929..1202934,1202938..1202940,
                     1202950..1202955,1202962..1202964,1203013..1203015,
                     1203055..1203060,1203067..1203069,1203088..1203099,
                     1203106..1203111,1203136..1203141,1203169..1203174,
                     1203181..1203186,1203190..1203195,1203202..1203207,
                     1203214..1203219)
                     /locus_tag="Smed_4686"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1202764..1202808,1203088..1203105)
                     /locus_tag="Smed_4686"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1202806..1202808,1202890..1202892,1203106..1203108,
                     1203130..1203132,1203139..1203141,1203169..1203171)
                     /locus_tag="Smed_4686"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1202965..1203003,1203019..1203024,1203034..1203036)
                     /locus_tag="Smed_4686"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1203272..1204402
                     /locus_tag="Smed_4687"
                     /db_xref="GeneID:5319329"
     CDS             1203272..1204402
                     /locus_tag="Smed_4687"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21198 putative oligopeptide uptake ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313417.1"
                     /db_xref="GI:150376821"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319329"
                     /translation="MTDIAQIPASAPETRGRSLFQLAALRFRRNRPAMAGCVMLVLIG
                     LFSFVGPLFSPHSYDQVFPSYVTIGPSLEPRPDSSTLQDVMEGVASRARVRLTEFAVE
                     DQSFTATVTSDAPIDPRATRYFDRANEFENTKVVATEGDGRTLKVEGDVAREYFPFGT
                     DSNGRDLLVRVMLGGQISIAVGLLASLVSLGIGVLYGATSGYIGGRVDNVMMRFVEIL
                     YSLPFVFLVVVLVVFFGRSFILIFLVIGAVEWLDMARIVRGQTLALKRREFVGAAQAL
                     GLTDWQIIRRHIIPNTIGPVIVFVTVVVPKVILLESFLSFLGLGVQAPLTSWGALISE
                     GANNIQSAPWLLIFPAIFFVLTLFSLNFVGDGLRDALDPKDR"
     misc_feature    1203317..1203484
                     /locus_tag="Smed_4687"
                     /note="N-terminal TM domain of oligopeptide transport
                     permease C; Region: OppC_N; pfam12911"
                     /db_xref="CDD:221848"
     misc_feature    1203800..>1204156
                     /locus_tag="Smed_4687"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1203842..1203847,1203854..1203859,1203872..1203874,
                     1203902..1203913,1203917..1203946,1203953..1203958,
                     1203962..1203964,1204013..1204018,1204022..1204024,
                     1204028..1204030,1204037..1204042,1204046..1204048,
                     1204058..1204063,1204070..1204072,1204121..1204123)
                     /locus_tag="Smed_4687"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    1203920..1203964
                     /locus_tag="Smed_4687"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1204073..1204111,1204127..1204132,1204142..1204144)
                     /locus_tag="Smed_4687"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1204404..1206005
                     /locus_tag="Smed_4688"
                     /db_xref="GeneID:5319330"
     CDS             1204404..1206005
                     /locus_tag="Smed_4688"
                     /note="PFAM: ABC transporter related;
                     Oligopeptide/dipeptide ABC transporter domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21199 putative oligopeptide uptake ABC
                     transporter ATP-binding protein, consisting of 2 fused
                     ATP-binding domains"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313418.1"
                     /db_xref="GI:150376822"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013563"
                     /db_xref="GeneID:5319330"
                     /translation="MTEMQDAILAVRGLKVDFSTPDGTVEAVKGIDLDVRSGETLAVV
                     GESGSGKSQTMMGIMGLLANNGTVTGSALYRGQELVGLPPKALNRVRGSKITMIFQEP
                     MTSLDPLYTIGRQIAEPIVHHRGGTFKGARKRVLELLELVGIPEAQRRIDSYPHELSG
                     GQRQRVMIAMALANEPDILIADEPTTALDVTIQAQILDLLKALQTRFGMAIVLITHDL
                     GIVKHFAERVAVMRRGEVVEQGTTADIFERPEADYTRMLLEAEPSGHKAPPPDNAPII
                     LEGRNVGVDYTIPGGLFRGASTAFRAVDGVSLRLRQGQTIGIVGESGSGKSTLGRALL
                     RLLPSSGYYRFGSTDISGFDRGAMRPLRRQLQLVFQDPYGSLSPRRTVGEIITEGLHV
                     HEPDLSRADRDRRAIAALKEVGLDPASRNRYPHEFSGGQRQRIAIARAIILKPKVVIL
                     DEPTSALDRSVQGQVIALLRDLQEKHGLSYIFISHDLSVVKAMSDYVIVMKNGRIVEE
                     GETDAIFKAPREPYTKTLIGAAFNV"
     misc_feature    1204410..1206002
                     /locus_tag="Smed_4688"
                     /note="ABC-type uncharacterized transport system,
                     duplicated ATPase component [General function prediction
                     only]; Region: COG4172"
                     /db_xref="CDD:226641"
     misc_feature    1204425..1205123
                     /locus_tag="Smed_4688"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    1204536..1204559
                     /locus_tag="Smed_4688"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    order(1204545..1204550,1204554..1204562,1204701..1204703,
                     1204947..1204952,1205049..1205051)
                     /locus_tag="Smed_4688"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    1204692..1204703
                     /locus_tag="Smed_4688"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    1204875..1204904
                     /locus_tag="Smed_4688"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    1204935..1204952
                     /locus_tag="Smed_4688"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    1204959..1204970
                     /locus_tag="Smed_4688"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    1205037..1205057
                     /locus_tag="Smed_4688"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    1205112..>1205246
                     /locus_tag="Smed_4688"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     misc_feature    1205229..1205930
                     /locus_tag="Smed_4688"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    1205361..1205384
                     /locus_tag="Smed_4688"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    order(1205370..1205375,1205379..1205387,1205511..1205513,
                     1205754..1205759,1205856..1205858)
                     /locus_tag="Smed_4688"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    1205502..1205513
                     /locus_tag="Smed_4688"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    1205682..1205711
                     /locus_tag="Smed_4688"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    1205742..1205759
                     /locus_tag="Smed_4688"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    1205766..1205777
                     /locus_tag="Smed_4688"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    1205844..1205864
                     /locus_tag="Smed_4688"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    1205919..>1205993
                     /locus_tag="Smed_4688"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     gene            complement(1206152..1207495)
                     /locus_tag="Smed_4689"
                     /db_xref="GeneID:5319331"
     CDS             complement(1206152..1207495)
                     /locus_tag="Smed_4689"
                     /note="PFAM: response regulator receiver; sigma-54 factor
                     interaction domain-containing protein; helix-turn-helix
                     Fis-type;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21200 putative two-component response
                     regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="two component, sigma54 specific, Fis family
                     transcriptional regulator"
                     /protein_id="YP_001313419.1"
                     /db_xref="GI:150376823"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR002078"
                     /db_xref="InterPro:IPR002197"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319331"
                     /translation="MSESRILLVDDEEELRRSSAQALELAGFRVDTFACAEDALERIA
                     FSFHGVVISDIRMPGMDGMTFLQRIREIDAELPVILVTGHGDVQLAVRAMREGAYDFV
                     EKPFTAQMLAGTIRRALDWRALVLENRRLRAVAGKRDDIEQRLPGRSQAMVDLRYRVR
                     AIGASDADTLIIGETGVGKEVVARALHDLSSRARGPFIAINCAALPQNLIESELFGHE
                     PGAFPGALRPRYGKFEHGRGGTILLDEIGSMPFDLQAKFLRVLQERVITRLGSNETVS
                     LDVRFIATSKVDLEREVANGRFRADLLYRLNVATLRVPTLSQRRSDIPLLFMQLVRES
                     AARYGRDDVEISAALASDMASREWPGNVRELRNAAERLILGLEPESEEALAPANGQRL
                     AEKVAAFERSVIASALAAHGGALKPVYESLGISRKTLYEKMQKFGLDKKALTEER"
     misc_feature    complement(1206170..1207495)
                     /locus_tag="Smed_4689"
                     /note="Response regulator containing CheY-like receiver,
                     AAA-type ATPase, and DNA-binding domains [Signal
                     transduction mechanisms]; Region: AtoC; COG2204"
                     /db_xref="CDD:225114"
     misc_feature    complement(1207139..1207477)
                     /locus_tag="Smed_4689"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(1207181..1207186,1207193..1207195,
                     1207250..1207252,1207310..1207312,1207334..1207336,
                     1207463..1207468))
                     /locus_tag="Smed_4689"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(1207334..1207336)
                     /locus_tag="Smed_4689"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    complement(order(1207310..1207318,1207322..1207327))
                     /locus_tag="Smed_4689"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    complement(1207178..1207186)
                     /locus_tag="Smed_4689"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(1206575..1207024)
                     /locus_tag="Smed_4689"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(1206956..1206979)
                     /locus_tag="Smed_4689"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(1206638..1206640,1206764..1206766,
                     1206953..1206976))
                     /locus_tag="Smed_4689"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(1206761..1206778)
                     /locus_tag="Smed_4689"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(1206581..1206583)
                     /locus_tag="Smed_4689"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(1206188..1206313)
                     /locus_tag="Smed_4689"
                     /note="Bacterial regulatory protein, Fis family; Region:
                     HTH_8; pfam02954"
                     /db_xref="CDD:202485"
     gene            complement(1207492..1209312)
                     /locus_tag="Smed_4690"
                     /db_xref="GeneID:5319332"
     CDS             complement(1207492..1209312)
                     /locus_tag="Smed_4690"
                     /note="PFAM: ATP-binding region ATPase domain protein;
                     histidine kinase A domain protein;
                     KEGG: sme:SMb21201 putative two-component sensor histidine
                     kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane sensor signal transduction
                     histidine kinase"
                     /protein_id="YP_001313420.1"
                     /db_xref="GI:150376824"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="GeneID:5319332"
                     /translation="MKYRFFLALLLVPAAAGLIAVQGNAVATRSYMQEASSQAHTALR
                     LAVAALSGHLNRYQALPALIADHDDVKELVTRPNDGELRGTVNSYLKEINGLLKSSDI
                     YVILPNGNTIAASNYDGPTSFVGENFSYRPYFQDALKGEQSRFYALGTTSLKRGYYFG
                     APVRIGGDIRGVIVFKVDIETIEASWQGGEYRIFVSDPEGIIFMSGNPEWLYAGILPL
                     TAERLARTEASRRYADAVLHQLPAVQSELSGHRVLRVSGGSDREYLVLSHYMPEADWT
                     VNVLADTGSVRTQALTTVAAVLLLLCLTGLAIAIFIQRRARLRERILMQEQAQEELER
                     RVEERTADLARVNTQIEAEIAERRLTEQQLRQTQADLIQAGKLAGLGQMSAALSHEFN
                     QPLAAAKTYADSAALLIERGRTAEASDNVRRISGLIDRMASISRHLRNFARKPNEKLG
                     PVRLDEVMHDTLEIVAARIKTAGAKMDIELDGDLMVRAGSVRLQQVLVNVISNAADAV
                     EGLDDRTLSVRAWREDGKAVLTVRDRGGGVAPSVAERIFDPFYTTKGVGRGLGLGLSI
                     SYNIIKDFGGSLTVSNHPEGGAVFRIELALAGQTGREAAE"
     sig_peptide     complement(1209235..1209312)
                     /locus_tag="Smed_4690"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.665 at
                     residue 26"
     misc_feature    complement(1207519..1209249)
                     /locus_tag="Smed_4690"
                     /note="Signal transduction histidine kinase regulating
                     C4-dicarboxylate transport system [Signal transduction
                     mechanisms]; Region: COG4191"
                     /db_xref="CDD:226654"
     misc_feature    complement(1207984..1208175)
                     /locus_tag="Smed_4690"
                     /note="Histidine Kinase A (dimerization/phosphoacceptor)
                     domain; Histidine Kinase A dimers are formed through
                     parallel association of 2 domains creating 4-helix
                     bundles; usually these domains contain a conserved His
                     residue and are activated via...; Region: HisKA; cd00082"
                     /db_xref="CDD:119399"
     misc_feature    complement(order(1207999..1208001,1208011..1208013,
                     1208020..1208022,1208032..1208034,1208041..1208043,
                     1208053..1208055,1208110..1208112,1208119..1208121,
                     1208131..1208133,1208140..1208142,1208152..1208154,
                     1208164..1208166))
                     /locus_tag="Smed_4690"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119399"
     misc_feature    complement(1208146..1208148)
                     /locus_tag="Smed_4690"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:119399"
     misc_feature    complement(1207531..1207836)
                     /locus_tag="Smed_4690"
                     /note="Histidine kinase-like ATPases; This family includes
                     several ATP-binding proteins for example: histidine
                     kinase, DNA gyrase B, topoisomerases, heat shock protein
                     HSP90, phytochrome-like ATPases and DNA mismatch repair
                     proteins; Region: HATPase_c; cd00075"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(1207543..1207545,1207549..1207554,
                     1207567..1207569,1207573..1207575,1207621..1207632,
                     1207699..1207704,1207708..1207710,1207714..1207716,
                     1207720..1207722,1207795..1207797,1207804..1207806,
                     1207816..1207818))
                     /locus_tag="Smed_4690"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(1207804..1207806)
                     /locus_tag="Smed_4690"
                     /note="Mg2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238030"
     misc_feature    complement(order(1207624..1207626,1207630..1207632,
                     1207702..1207704,1207708..1207710))
                     /locus_tag="Smed_4690"
                     /note="G-X-G motif; other site"
                     /db_xref="CDD:238030"
     gene            1209596..1210528
                     /locus_tag="Smed_4691"
                     /db_xref="GeneID:5319333"
     CDS             1209596..1210528
                     /locus_tag="Smed_4691"
                     /note="PFAM: Glyoxalase/bleomycin resistance
                     protein/dioxygenase;
                     KEGG: sme:SMb21202 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance
                     protein/dioxygenase"
                     /protein_id="YP_001313421.1"
                     /db_xref="GI:150376825"
                     /db_xref="InterPro:IPR004360"
                     /db_xref="InterPro:IPR011588"
                     /db_xref="GeneID:5319333"
                     /translation="MLEQIKGLHHVTSMAEDARTNNQFFTQTLGLRRVKKTVNFDSPD
                     VYHLYYGDETGTAGTVMTYFPFPEMPRGRAGTGEVGTTAFSVPQGSLGFWEGRLTRLG
                     VSGLKRSESFGEKRLNFAGPDGDGFALVEVRDDPRTPWTEGGLSGDYAIRGFHSVAMR
                     LRDEGATADLLKYMGYEELDRRDGVTRLVVPDGNGANLVDLETLPGINRAAQGAGSVH
                     HVAFAVDNRERQLEIRKALMDTGYHVTPVIDRDYFWAIYFRTPGGVLFEIATNEPGFD
                     RDEDTAHLGEALKLPQQHKHLRPILEGHLQRLEA"
     misc_feature    1209614..1209985
                     /locus_tag="Smed_4691"
                     /note="N-terminal domain of Sphingobium chlorophenolicum
                     2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and
                     similar proteins; Region: PcpA_N_like; cd08346"
                     /db_xref="CDD:211356"
     misc_feature    1209614..1209967
                     /locus_tag="Smed_4691"
                     /note="Glyoxalase/Bleomycin resistance protein/Dioxygenase
                     superfamily; Region: Glyoxalase; pfam00903"
                     /db_xref="CDD:216182"
     misc_feature    order(1209623..1209625,1209629..1209631)
                     /locus_tag="Smed_4691"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:211356"
     misc_feature    1210052..1210510
                     /locus_tag="Smed_4691"
                     /note="C-terminal domain of Sphingobium chlorophenolicum
                     2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and
                     similar proteins; Region: PcpA_C_like; cd08347"
                     /db_xref="CDD:176695"
     misc_feature    order(1210250..1210252,1210394..1210396)
                     /locus_tag="Smed_4691"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:176695"
     gene            1210644..1211246
                     /locus_tag="Smed_4692"
                     /db_xref="GeneID:5318831"
     CDS             1210644..1211246
                     /locus_tag="Smed_4692"
                     /note="PFAM: phospholipase/Carboxylesterase;
                     KEGG: sme:SMb21203 putative esteraselipase/thioesterase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase/carboxylesterase"
                     /protein_id="YP_001313422.1"
                     /db_xref="GI:150376826"
                     /db_xref="InterPro:IPR003140"
                     /db_xref="GeneID:5318831"
                     /translation="MPDHGYMHKLKAGSPGGPILFVFHGTGGDENQFFDFGAQLLPKA
                     TVVSPRGDVSEHGAARFFRRTGEGVYDMADLARATEKMAGFVKALASEYEASEIIGLG
                     YSNGANILANVLIEEGLFDKAVLMHPLIPFRPKANAALAGRKILITAGERDPICPAPL
                     TQALGDYLSQQNAAVELKWHSGGHDIRQNEIAATEEFLRV"
     misc_feature    1210644..1211237
                     /locus_tag="Smed_4692"
                     /note="Predicted esterase [General function prediction
                     only]; Region: COG0400"
                     /db_xref="CDD:223477"
     gene            1211325..1211567
                     /locus_tag="Smed_4693"
                     /db_xref="GeneID:5318832"
     CDS             1211325..1211567
                     /locus_tag="Smed_4693"
                     /note="TIGRFAM: prevent-host-death family protein;
                     KEGG: tbd:Tbd_2423 prevent-host-death protein"
                     /codon_start=1
                     /transl_table=11
                     /product="prevent-host-death family protein"
                     /protein_id="YP_001313423.1"
                     /db_xref="GI:150376827"
                     /db_xref="InterPro:IPR006442"
                     /db_xref="GeneID:5318832"
                     /translation="MIETVNIHQAKTNLSRLIEKAAKGEPFIIAKAGKPMVKVIPLDQ
                     PSDAKVQRIGFMAGQFSVPDDFDRMGRDEIEGLFGA"
     misc_feature    1211325..1211561
                     /locus_tag="Smed_4693"
                     /note="Antitoxin of toxin-antitoxin stability system [Cell
                     division and chromosome partitioning]; Region: Phd;
                     COG4118"
                     /db_xref="CDD:226603"
     gene            1211619..1211948
                     /locus_tag="Smed_4694"
                     /db_xref="GeneID:5318833"
     CDS             1211619..1211948
                     /locus_tag="Smed_4694"
                     /note="KEGG: hha:Hhal_0789 PilT protein domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="PilT domain-containing protein"
                     /protein_id="YP_001313424.1"
                     /db_xref="GI:150376828"
                     /db_xref="GeneID:5318833"
                     /translation="MSNEARALIEGPGNTLDFSAASVWEIAIKRGLGRMDFDADPRLL
                     RRGLLDNGYQELRVEGTHAVALDQLPPIHQEPFDRIAIAQSLVEGFTLVTSDEVVSRY
                     PGPSRVV"
     misc_feature    1211622..1211945
                     /locus_tag="Smed_4694"
                     /note="PIN domain of the VapC-like Sll0205 protein and
                     homologs; Region: PIN_Sll0205; cd09872"
                     /db_xref="CDD:189042"
     misc_feature    order(1211691..1211693,1211850..1211852,1211904..1211906)
                     /locus_tag="Smed_4694"
                     /note="putative active site [active]"
                     /db_xref="CDD:189042"
     gene            complement(1211952..1213064)
                     /locus_tag="Smed_4695"
                     /db_xref="GeneID:5318834"
     CDS             complement(1211952..1213064)
                     /locus_tag="Smed_4695"
                     /note="PFAM: ABC-2 type transporter;
                     KEGG: sme:SMb21204 putative ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 type transporter"
                     /protein_id="YP_001313425.1"
                     /db_xref="GI:150376829"
                     /db_xref="InterPro:IPR000412"
                     /db_xref="InterPro:IPR013525"
                     /db_xref="GeneID:5318834"
                     /translation="MWWTRLKALIVKELLAVLRDPKGRTILIGPPIIQLLVFSYAATL
                     EVTDVDIMVLNRDNGQWSQELIQLVGGSPTFRSIELASSPAEVRLAIDTQRVIAAVEI
                     GPTFSRDIEAGRPAEVQLILDGRRSNASQIVSGYLGRIVSTLAAETPAGKRAPSETVQ
                     VVARNWFNPNLTYQWFMVPNLVASIALLIGLIVTALSVARERELGTFDQLIVSPLRTH
                     EILLGKLIPPMMIGLFHITIYILAAVFVFGVPLRGSLFLLYGSAVFYLAAVVGLGLFI
                     SALSKTQQQAILGAFLFMVPAMLLSGFATPIENMPSWLQPVTLINPLRYFLVIVKGVF
                     LKDIPLYEVVHQTLPLCLIAIVTLSSAAWLFRKRLE"
     misc_feature    complement(1211955..1212851)
                     /locus_tag="Smed_4695"
                     /note="ABC-type multidrug transport system, permease
                     component [Defense mechanisms]; Region: COG0842"
                     /db_xref="CDD:223912"
     misc_feature    complement(1212060..1212569)
                     /locus_tag="Smed_4695"
                     /note="ABC-2 type transporter; Region: ABC2_membrane;
                     pfam01061"
                     /db_xref="CDD:216273"
     gene            complement(1213066..1214220)
                     /locus_tag="Smed_4696"
                     /db_xref="GeneID:5318835"
     CDS             complement(1213066..1214220)
                     /locus_tag="Smed_4696"
                     /note="PFAM: ABC-2 type transporter;
                     KEGG: sme:SMb21205 putative ABC transporter permease
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 type transporter"
                     /protein_id="YP_001313426.1"
                     /db_xref="GI:150376830"
                     /db_xref="InterPro:IPR000412"
                     /db_xref="InterPro:IPR013525"
                     /db_xref="GeneID:5318835"
                     /translation="MKDQGKKAQAYKSSGRARRFAALVRKESYQVVRDPSSILIAFVL
                     PLVLLFLFGYGVSLDTTRTRVALVVEETSPLTRDLAASFEASRYFSVVAGRDRREFED
                     ELVLGHVRGIVVIPAGFAADHAAARHPSVQVIVDGSDPNTANFVQNYAQGTVANWERQ
                     RMSEGRSMPPAISTEQRFWFNPQLTSRNFLVPGSIAIVMTLVGTLLTSLVVAREWERG
                     TMEAMMATPVSAAELLAGKLLPYFVLGLTSMTLCVLLAVFVFDVPFRGSVAALYALSA
                     TFLMPALGQGLLISAATKNQFLASQLALISAFLPAFLLSGFLFEINSMPTVIQWITYA
                     VPASYLIPSLQTVFLAGDIWPMFARAIAVMFLIGCMFFALAARSTRKRIG"
     misc_feature    complement(1213072..1213842)
                     /locus_tag="Smed_4696"
                     /note="ABC-type multidrug transport system, permease
                     component [Defense mechanisms]; Region: COG0842"
                     /db_xref="CDD:223912"
     misc_feature    complement(1213075..>1213587)
                     /locus_tag="Smed_4696"
                     /note="ABC-2 family transporter protein; Region:
                     ABC2_membrane_2; pfam12679"
                     /db_xref="CDD:221706"
     gene            complement(1214217..1215965)
                     /locus_tag="Smed_4697"
                     /db_xref="GeneID:5318836"
     CDS             complement(1214217..1215965)
                     /locus_tag="Smed_4697"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21206 putative ABC transporter ATP-binding
                     protein, consisting of 2 fused ATP-binding domains"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313427.1"
                     /db_xref="GI:150376831"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318836"
                     /translation="MTAMATALDTTPFVRLTSVTKRFGSAAPALDAVAGDILGGRITG
                     IVGPDGAGKTTLIRLMTALMLPDAGSVEVLGYDTRSDPAGIQASIGYMPQRFGLYEDL
                     SVQENLDLYADLRGLPKSERSRTFGELLEFTDLARFTTRLAGKLSGGMKQKLGLACAL
                     LRKPRLLLLDEPGVGVDPISRRDLWKMVENLKAEGIGVVWSTAYLEEAEACDHVFLLN
                     QGRLLFSGPPAEMTGRVENRVFRLSGIRGRRREKLAHFLEMEGVVDGVIQGEAIRLVM
                     KPGLQPFQSREATGAYCAAVTPPRFEDAFVDMLGGGPGGRSRLAETQRAFASEDGRSV
                     IEARGLTKRFGDFTAADNITFDIPRGEIFGLLGPNGAGKSTTFKMLCGLLTPTAGDGR
                     VAGFDLRRDAPAARNRLGYMAQKFSLYGDLSVIQNLNFFAGVYGLAGARKRERIALMG
                     EIFDFRSVLDMSAKDLPLGVKQRLALACAVLHEPEVLFLDEPTSGVDPITRREFWTHI
                     NGLVEKGVTVLVTTHFMDEAEYCDRISLIYRGRSIALGSPDEMKARIASEDLPDPTME
                     DAFIALVQGSEAKDAA"
     misc_feature    complement(1215033..1215935)
                     /locus_tag="Smed_4697"
                     /note="ABC-type multidrug transport system, ATPase
                     component [Defense mechanisms]; Region: CcmA; COG1131"
                     /db_xref="CDD:224054"
     misc_feature    complement(1215300..1215926)
                     /locus_tag="Smed_4697"
                     /note="ATP-binding cassette domain of the drug resistance
                     transporter and related proteins, subfamily A; Region:
                     ABC_DR_subfamily_A; cd03230"
                     /db_xref="CDD:213197"
     misc_feature    complement(1215804..1215827)
                     /locus_tag="Smed_4697"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(order(1215357..1215359,1215453..1215458,
                     1215684..1215686,1215801..1215809,1215813..1215818))
                     /locus_tag="Smed_4697"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1215684..1215695)
                     /locus_tag="Smed_4697"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1215501..1215530)
                     /locus_tag="Smed_4697"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1215453..1215470)
                     /locus_tag="Smed_4697"
                     /note="Walker B; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1215435..1215446)
                     /locus_tag="Smed_4697"
                     /note="D-loop; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1215351..1215371)
                     /locus_tag="Smed_4697"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1214235..1214966)
                     /locus_tag="Smed_4697"
                     /note="ABC-type Na+ transport system, ATPase component
                     [Energy production and conversion / Inorganic ion
                     transport and metabolism]; Region: NatA; COG4555"
                     /db_xref="CDD:226927"
     misc_feature    complement(1214343..1214963)
                     /locus_tag="Smed_4697"
                     /note="ATP-binding cassette domain of the drug resistance
                     transporter and related proteins, subfamily A; Region:
                     ABC_DR_subfamily_A; cd03230"
                     /db_xref="CDD:213197"
     misc_feature    complement(1214844..1214867)
                     /locus_tag="Smed_4697"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(order(1214397..1214399,1214493..1214498,
                     1214724..1214726,1214841..1214849,1214853..1214858))
                     /locus_tag="Smed_4697"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1214724..1214735)
                     /locus_tag="Smed_4697"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1214541..1214570)
                     /locus_tag="Smed_4697"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1214493..1214510)
                     /locus_tag="Smed_4697"
                     /note="Walker B; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1214475..1214486)
                     /locus_tag="Smed_4697"
                     /note="D-loop; other site"
                     /db_xref="CDD:213197"
     misc_feature    complement(1214391..1214411)
                     /locus_tag="Smed_4697"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213197"
     gene            complement(1215965..1216969)
                     /locus_tag="Smed_4698"
                     /db_xref="GeneID:5318837"
     CDS             complement(1215965..1216969)
                     /locus_tag="Smed_4698"
                     /note="PFAM: secretion protein HlyD family protein;
                     KEGG: sme:SMb21207 putative protein secretion protein,
                     HlyD family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313428.1"
                     /db_xref="GI:150376832"
                     /db_xref="InterPro:IPR006143"
                     /db_xref="GeneID:5318837"
                     /translation="MKKIALIVVILAAAVAGAWWFDLPVRLGFAGETRQAVLYGNVDI
                     RQVSLGFRVSGRIAELRVDEGDSVRKGDVIARLDDEPFRQTLDASEAEAEASRATLTK
                     LKAGARAGEIAQARATHEERLAELENAELAYERAKQLRPNGTISQAELDQSSAGRAAA
                     AARARSAREGLALLEEGSRVEDITSAEAQVDAAAAKAASARTSLKDTELVAPNDGVVL
                     SRVRETGAIVSPADVVYVLSLTEPVWVRAYVAEPDLGRLYPGMKVTIASDTAPGRAYE
                     GTVGFISPVAEFTPKSVETPELRTDLVYRLRIVITNPGKDLRQGMPVTVQLPETKEAS
                     "
     sig_peptide     complement(1216913..1216969)
                     /locus_tag="Smed_4698"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.893 at
                     residue 19"
     misc_feature    complement(1215968..1216921)
                     /locus_tag="Smed_4698"
                     /note="putative efflux pump membrane fusion protein;
                     Provisional; Region: PRK03598"
                     /db_xref="CDD:235136"
     misc_feature    complement(1216709..1216837)
                     /locus_tag="Smed_4698"
                     /note="Biotin-lipoyl like; Region: Biotin_lipoyl_2;
                     pfam13533"
                     /db_xref="CDD:205711"
     misc_feature    complement(1216010..1216348)
                     /locus_tag="Smed_4698"
                     /note="HlyD family secretion protein; Region: HlyD_3;
                     pfam13437"
                     /db_xref="CDD:222128"
     gene            complement(1216966..1217670)
                     /locus_tag="Smed_4699"
                     /db_xref="GeneID:5318838"
     CDS             complement(1216966..1217670)
                     /locus_tag="Smed_4699"
                     /note="PFAM: regulatory protein TetR; Transcriptional
                     regulator TetR;
                     KEGG: sme:SMb21208 putative transcriptional regulator,
                     TetR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_001313429.1"
                     /db_xref="GI:150376833"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR015292"
                     /db_xref="GeneID:5318838"
                     /translation="MKKDANRPTIPRGDRGDATREKLLIIAIDVFGRYGFDGATTRKL
                     ADAAGVNLQAIPYYFGGKEGLYIAAAEHLASAIGGHVGDLRSTIVSRIAELDAAGAQL
                     TSAEARHFLTQMVQRMIILFVSKQSESWARFIIREQMEPTEAFRRIYGSIMGPMIEMA
                     RRLIGAILHDDPASEHIRLRTLSFVGSILVFRMAHAAVYAQLEWETAGPKEIETLHRH
                     AVELVAVLGAEKDRRS"
     misc_feature    complement(1217020..1217649)
                     /locus_tag="Smed_4699"
                     /note="putative DNA-binding transcriptional regulator;
                     Provisional; Region: PRK11552"
                     /db_xref="CDD:236928"
     misc_feature    complement(1217464..1217604)
                     /locus_tag="Smed_4699"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:201228"
     misc_feature    complement(1216993..1217352)
                     /locus_tag="Smed_4699"
                     /note="Domain of unknown function (DUF1956); Region:
                     DUF1956; pfam09209"
                     /db_xref="CDD:220143"
     gene            1217856..1218248
                     /locus_tag="Smed_4700"
                     /db_xref="GeneID:5318839"
     CDS             1217856..1218248
                     /locus_tag="Smed_4700"
                     /note="PFAM: Glyoxalase/bleomycin resistance
                     protein/dioxygenase;
                     KEGG: sme:SMc01989 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance
                     protein/dioxygenase"
                     /protein_id="YP_001313430.1"
                     /db_xref="GI:150376834"
                     /db_xref="InterPro:IPR004360"
                     /db_xref="InterPro:IPR011588"
                     /db_xref="GeneID:5318839"
                     /translation="MRFINPIPFVRDISRSKEFYRDILGIKVLKDFGDFVLFETGFAI
                     HAGSSLERTVWRMASKSEESYGRRNLLLYFEHDDVEAAFENIARHVELIHPIERQAWG
                     QRVFRFYDPDGHAIEVGEPQDLGGLHGS"
     misc_feature    1217856..1218221
                     /locus_tag="Smed_4700"
                     /note="This domain superfamily is found in a variety of
                     structurally related metalloproteins, including the type I
                     extradiol dioxygenases, glyoxalase I and a group of
                     antibiotic resistance proteins; Region: Glo_EDI_BRP_like;
                     cl14632"
                     /db_xref="CDD:246679"
     misc_feature    order(1217868..1217870,1217880..1217882,1217958..1217960,
                     1217982..1217984,1217988..1217990,1218066..1218068,
                     1218174..1218176,1218198..1218200,1218204..1218206)
                     /locus_tag="Smed_4700"
                     /note="active site"
                     /db_xref="CDD:211348"
     misc_feature    order(1217868..1217870,1218066..1218068,1218204..1218206)
                     /locus_tag="Smed_4700"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:211348"
     misc_feature    1217880..1218209
                     /locus_tag="Smed_4700"
                     /note="Glyoxalase/Bleomycin resistance protein/Dioxygenase
                     superfamily; Region: Glyoxalase; pfam00903"
                     /db_xref="CDD:216182"
     gene            1218387..1218767
                     /locus_tag="Smed_4701"
                     /db_xref="GeneID:5318840"
     CDS             1218387..1218767
                     /locus_tag="Smed_4701"
                     /note="KEGG: sme:SMb21212 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313431.1"
                     /db_xref="GI:150376835"
                     /db_xref="GeneID:5318840"
                     /translation="MQIAGIQVYPERGGKAGFTIEFVGANGEVISVSCPQNAEGSLNR
                     LNAVARAKEILSAAIDADETLLAITGTKRSPSVPEGALANARQSHDQYAMEEQLEEGL
                     EDTFPASDPVSITSSAIPKGSSGR"
     gene            1218971..1219630
                     /locus_tag="Smed_4702"
                     /db_xref="GeneID:5318841"
     CDS             1218971..1219630
                     /locus_tag="Smed_4702"
                     /note="PFAM: metallophosphoesterase;
                     KEGG: sme:SMb21213 putative serinethreonine protein
                     phosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase"
                     /protein_id="YP_001313432.1"
                     /db_xref="GI:150376836"
                     /db_xref="InterPro:IPR004843"
                     /db_xref="InterPro:IPR006186"
                     /db_xref="GeneID:5318841"
                     /translation="MNGRRLTFAVGDIHGCLAQLETLLASIESIAAGGRVIFLGDLVD
                     RGPDSRGVVERIMAGPRTTGWKWITLKGNHEAMLVAARKGRPEMSLWLINGGEETMAS
                     YGGAIPLSHLVWMAELPSIIIERHRIFVHAGVDENIPLDEQGDDILLWMRTDPNYSGT
                     YWGRHVCHGHTPSRSNPRTVGNRTNVDSGAVFGGMLSCAVFDDDRAGGPIDFLVTDGY
                     G"
     misc_feature    1218992..1219573
                     /locus_tag="Smed_4702"
                     /note="phosphoprotein phosphatases of the
                     metallophosphatase superfamily, metallophosphatase domain;
                     Region: MPP_PPP_family; cd00144"
                     /db_xref="CDD:163613"
     misc_feature    1218995..1219483
                     /locus_tag="Smed_4702"
                     /note="Calcineurin-like phosphoesterase; Region:
                     Metallophos; pfam00149"
                     /db_xref="CDD:215750"
     misc_feature    order(1219004..1219006,1219010..1219012,1219091..1219093,
                     1219103..1219105,1219187..1219192,1219361..1219363,
                     1219418..1219420,1219478..1219480)
                     /locus_tag="Smed_4702"
                     /note="active site"
                     /db_xref="CDD:163613"
     misc_feature    order(1219004..1219006,1219010..1219012,1219091..1219093,
                     1219187..1219189,1219361..1219363,1219478..1219480)
                     /locus_tag="Smed_4702"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163613"
     gene            1219795..1220469
                     /locus_tag="Smed_4703"
                     /db_xref="GeneID:5318853"
     CDS             1219795..1220469
                     /locus_tag="Smed_4703"
                     /note="TIGRFAM: HAD-superfamily hydrolase, subfamily IA,
                     variant 3; HAD-superfamily hydrolase, subfamily IA,
                     variant 1;
                     PFAM: Haloacid dehalogenase domain protein hydrolase;
                     KEGG: sme:SMb21214 putative 2-deoxyglucose-6-phosphate
                     phosphatase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="YP_001313433.1"
                     /db_xref="GI:150376837"
                     /db_xref="InterPro:IPR000150"
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006402"
                     /db_xref="InterPro:IPR006439"
                     /db_xref="GeneID:5318853"
                     /translation="MDTSSSAIFTKNFAALLFDMDGTLLNSMAVVERVWGSWAARNGI
                     DPVALMKVVHGVRAVDTIRALGLSVDPEQEARILAEAEIADVDGIVEIPGAVTFLKTL
                     PPEKWAIVTSAPLELAARRLEAAGIPVPRLMVTGEDVTVGKPDPQGYLLAAERLGVRA
                     EDCLVFEDAPAGVLAGKSAGAEVAVITGAHAAAAELPHVMLAHYSDVEARLVEDGWLS
                     LHRRRG"
     misc_feature    1219831..1220334
                     /locus_tag="Smed_4703"
                     /note="beta-phosphoglucomutase family hydrolase; Region:
                     PGMB-YQAB-SF; TIGR02009"
                     /db_xref="CDD:213673"
     misc_feature    1219837..1220334
                     /locus_tag="Smed_4703"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    1219849..1219866
                     /locus_tag="Smed_4703"
                     /note="motif I; other site"
                     /db_xref="CDD:119389"
     misc_feature    1219849..1219857
                     /locus_tag="Smed_4703"
                     /note="active site"
                     /db_xref="CDD:119389"
     gene            complement(1220545..1221498)
                     /locus_tag="Smed_4704"
                     /db_xref="GeneID:5318854"
     CDS             complement(1220545..1221498)
                     /locus_tag="Smed_4704"
                     /note="KEGG: sme:SMb21307 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313434.1"
                     /db_xref="GI:150376838"
                     /db_xref="GeneID:5318854"
                     /translation="MLVYADENLEVIHRRGGSPYLLVTFNEMEMQANGSRFWGQRFCE
                     KADIAALGFISRRPNWFPAASVVAAVRAAAPILAAAPERILYGHSQGGYAALRYRRRF
                     GAAVAIAFCPQISIDPKAVPFDNRFIRHFAADLHGKMGIAADQAAGRAYLFYDPFHTV
                     DRRHAERIAAIQEDTHLIPVHMTGHGTVRAFAGTARALSLIEACRNDDRAGLKALARS
                     ARVGATMRPYQIAVAAIARHPAWADRFLQRFGHGFSLVERVNFLYHRANRHIRDGELS
                     VARAMLAQAVALQPTNAGFARRLEELESRMSRARVATLEAV"
     gene            complement(1221542..1222864)
                     /locus_tag="Smed_4705"
                     /db_xref="GeneID:5318855"
     CDS             complement(1221542..1222864)
                     /locus_tag="Smed_4705"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21308 putative glycosyltransferase, forming
                     alpha glycosyl linkages protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313435.1"
                     /db_xref="GI:150376839"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318855"
                     /translation="MSERLRILVVSHGHPAMSLGGAEIASHSLHKGLNTLAGVESIYL
                     ARVSHPIPRHGASALMSLRLAVDEVLFHADDYDHFFLSNGDTEAIRRDLLRFVGDLSP
                     HIIHFHHLIGMGIEALYALREALPEAAIVVTFHEYLSLCHNHGQMVKRPSAQLCNSSS
                     PISCHGCFPDIPVSRFLRREEFLRGMLGLSDAFISPSMFLATRYAEWGIDPEKLSVIE
                     NGIVLGEAAPIRDLPVPSARRNRFAYFGQITPFKGIDVLVDAVSRVPEKIWGEDSCLM
                     IFGANLERQPPEFQERLKKLIDEAGRRVRFYGAYQNGDMARLMRSVDWVVLPSIWWEN
                     SPVVIQEALHHRRPVICSDIGGMAEKVRDGRDGLHFRAGSAQDLADRLAEVLGNPDMW
                     DRLHAMLRQPTSHMESARAHADLYRRLLDDKRGPMRAEQYDALAQAVP"
     misc_feature    complement(1221587..1222849)
                     /locus_tag="Smed_4705"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    complement(1221611..1222849)
                     /locus_tag="Smed_4705"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. ExpE7 in Sinorhizobium
                     meliloti has been shown to be involved in the biosynthesis
                     of galactoglucans (exopolysaccharide II); Region:
                     GT1_ExpE7_like; cd03823"
                     /db_xref="CDD:99993"
     gene            complement(1222861..1225068)
                     /locus_tag="Smed_4706"
                     /db_xref="GeneID:5318856"
     CDS             complement(1222861..1225068)
                     /locus_tag="Smed_4706"
                     /note="KEGG: sme:SMb21309 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313436.1"
                     /db_xref="GI:150376840"
                     /db_xref="GeneID:5318856"
                     /translation="MSDAEQALPATSHTATRIMRGGRVAACPIDDGLLLVIGASGPAA
                     GQLPAEINDDAATVTNAYVTAWRLASPSPSVTHGFAALLPTDDADRPLTTLRLGQEGR
                     RYIFAPRTLAVREAVTILAELSGGQLTAVLDSLVDAMIQITAGRRRLAVIVALIQSRK
                     GGDGFLEFVGETHEGSIFLRGWARAADPGNTQVIVCGENPVFADCAIATFSRQDIPKG
                     AVGFIGLLAASEPFRARDVEGLVYRGGGGWRYAALHQSRQIAGPAETPAQIRSVLLQT
                     HSSPAVLLKLRSAANSFEGRETISTLPVPVRLGVDNIFQANSGAFLISGWLLDPDGHV
                     QSVRLRRGSTDMRLDDRWTRLERSDVTDAFSDEPLFKSMLDQDTHPHGFIVFASGLGE
                     DGMAPLHLELTLKDSRRAFLPLTPARLPPRRAVLRQIKSIDPENWGLAEIVDRQIVPF
                     LCASESPSPTAGNILDAGAFDDAPGPPIIVAVGQTEERELAPFLGLLALDPETRQAPI
                     ALVLNSECFRRQAARIRQLAQFYRLSLRLMSSETDDVYDLLEAGIRALPSETVVLLAG
                     SLLPRRSGWYGNLLAAYEEKGGVISPTLAYEDHSVRWAGTWADPQSGSLSGRYAGYPL
                     SAVTGLKLTRIAAASFECCILPREVFLTAGGFAGSYLGSQQKGQDLGLRLSRIGIESW
                     WLPSVQMLGSDEISAPDGASAAPLIERIDEKLFSARWAPGPESRDNRMVEASA"
     gene            complement(1225079..1225786)
                     /locus_tag="Smed_4707"
                     /db_xref="GeneID:5318857"
     CDS             complement(1225079..1225786)
                     /locus_tag="Smed_4707"
                     /note="KEGG: sme:SMb21310 putative membrane-anchored
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane-anchored protein"
                     /protein_id="YP_001313437.1"
                     /db_xref="GI:150376841"
                     /db_xref="GeneID:5318857"
                     /translation="MAAVSEKSNAAPEQDNTKPMSGRVDAIDQGRIFGWAFDPAAPTK
                     RLTIRVYVDGSAIAEAVADRNRPDLKRNGIGDGSHAFEIALPEAAASRAADLTVTALD
                     ARGTEQKLRVPRPDEQAAEALIAAPLAKVLDKLDVLMAAQRQLQVSQRSFQRTQNDEG
                     GEGGTLRPGAAAEIGQRLNDLDVHLMRLDGVVAAMEKNLGALQKRSNGELKPLLLLLF
                     VLAGFAAGAALSLFAGA"
     gene            complement(1225798..1227054)
                     /locus_tag="Smed_4708"
                     /db_xref="GeneID:5318858"
     CDS             complement(1225798..1227054)
                     /locus_tag="Smed_4708"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21311 putative glycosyltransferase, forming
                     alpha-gylcosyl linkages protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313438.1"
                     /db_xref="GI:150376842"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318858"
                     /translation="MRVLVAAHNHPALHPGGTEIFAHDLFRAYKRAGCESLFLGATNQ
                     IHRQARPGTSFQGIGPAGDELLLWSGHFDRFFMSQIDLYGVVPDLAELLRDFRPDVVH
                     IHHLLLLGAEFPHIVRRTLPECRIVMTLHDYYPICHHDGLMVRTSGKELCHGASPDRC
                     HACFKDIALDRFALRERHLKALLSDVDRFVSPSNFLKTRFVEWGLSEDAISVIPNGLP
                     PRKEPAAVRRIGSDRPIFGYFGNLNPWKGVAVLLEAARQLIAEGLEFELRVHGGAPFQ
                     SESFVEEITRLFQETAPTVQQRGPYRREDVIDLVASVDCTIVPSIWWENAPLVIQEAQ
                     ALGRPVIASNIGGMAELIEDGSNGLTVAPNDPRALASAMRRLAQDGGLARRLAANAHE
                     PENIDTTARRYLELIDTIAPSRIEAA"
     misc_feature    complement(1225825..1227054)
                     /locus_tag="Smed_4708"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    complement(1225828..1227051)
                     /locus_tag="Smed_4708"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. ExpE7 in Sinorhizobium
                     meliloti has been shown to be involved in the biosynthesis
                     of galactoglucans (exopolysaccharide II); Region:
                     GT1_ExpE7_like; cd03823"
                     /db_xref="CDD:99993"
     gene            complement(1227057..1227902)
                     /locus_tag="Smed_4709"
                     /db_xref="GeneID:5318859"
     CDS             complement(1227057..1227902)
                     /locus_tag="Smed_4709"
                     /note="PFAM: Methyltransferase type 11; Methyltransferase
                     type 12;
                     KEGG: sme:SMb21312 putative methyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="type 11 methyltransferase"
                     /protein_id="YP_001313439.1"
                     /db_xref="GI:150376843"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="GeneID:5318859"
                     /translation="MTETALRQENTHATDLPARDERVETLLGSILRNRFLPEPNPDSV
                     FVGDGDFRAVGVEFLGHFIRLAGLRPESRVLDIGCGIGRMAVPLTQYLDFEKGRYSGI
                     DPVEGGIAWCRRFITPAYQNFAFQRVDIAHELYNPSGKISGNALKLPYADGHFDFVIM
                     TSIVTHLPPDEVLVYLREVGRLLKPGGRLFMTAFVVDDVAAANESGRRDARLSFARDG
                     EGPCWYVPEMPRLAAVGFDEGFLDGALERAGLKINLKSLGAWRGVSAEHYQDIFVAER
                     RGSGP"
     misc_feature    complement(1227147..1227734)
                     /locus_tag="Smed_4709"
                     /note="Methyltransferase domain; Region: Methyltransf_23;
                     pfam13489"
                     /db_xref="CDD:222171"
     misc_feature    complement(1227315..1227686)
                     /locus_tag="Smed_4709"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(1227420..1227422,1227468..1227476,
                     1227591..1227596,1227654..1227674))
                     /locus_tag="Smed_4709"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(1227899..1230148)
                     /locus_tag="Smed_4710"
                     /db_xref="GeneID:5318860"
     CDS             complement(1227899..1230148)
                     /locus_tag="Smed_4710"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb21313 putative bifunctional
                     glycosyltransferase, forming alpha-glycosyl and
                     beta-glycosyl linkages protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313440.1"
                     /db_xref="GI:150376844"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318860"
                     /translation="MTFDDRMGAASGIFEDAKVFRLGSEVAVLISDLKKKLPAAAKHR
                     LVMPEQPVPLVSTILPLAEGGQRVLWAMRPGGEPRRGQISVDSDFVRTVVLQPVGELP
                     PLDVEALFAALTPEGCVKFVNTLLTVWRSAFRLSRDAFFIGLVEDALHALTSRPRPAK
                     IACPIMPGRYLIETAITPDFGEISAVYSLGANAVLPLESQAVTGPDREHDLRPCHFIV
                     ESPRHPQSYVLVGKRGVAVRELSSGKPHYTSLQAWWAERGGAPELREFVVRWLSTTPE
                     GGHSTAVDLQLRTPLPARRIDRSSMHPSAEVDLALSLSGGLLAGGWSHDPTATLAGID
                     YLNENGTAVPLDGNWYEFPAWARGTDDNTRADVTGFVAWLPLNEAPGALLQPRFQMRL
                     ASGVVKPLVPKPQPFEASAQRNRILRAVPPQHAVDLAFRTILAPALQDVEHRLGRTAT
                     VDYTKDYDLPQTAPLVSIVVPLYRVLDFLRFQLSGMATDRWLAKNVEIIYVLDSPEIQ
                     DETEHLLGGLHLLHGLPMKLVVMSRNGGYARACNAGARFARGAVIVMLNSDVVPSAAG
                     WLQRLIRPLMEQKSLGAIGPKLIFEDGSLQHAGLYFARDQRGIWLNHHFHKGMPGDYA
                     PAQFSRSVPGITGACLVTRRETYERVDGYTEDYVIGDYEDSDLCLKIRRCGYDIVYEP
                     SACLYHFERRSIRRSEDYMRGVASQYNSWLHTERWDDDIEALMAAYLGSGIQGLVRQE
                     AGATARSAA"
     misc_feature    complement(1228007..1228759)
                     /locus_tag="Smed_4710"
                     /note="Glycosyltransferase like family 2; Region:
                     Glyco_tranf_2_3; pfam13641"
                     /db_xref="CDD:222281"
     misc_feature    complement(1228079..1228747)
                     /locus_tag="Smed_4710"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cl11394"
                     /db_xref="CDD:245596"
     misc_feature    complement(order(1228472..1228474,1228478..1228480,
                     1228646..1228648,1228730..1228732,1228736..1228738))
                     /locus_tag="Smed_4710"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            complement(1230274..1230933)
                     /locus_tag="Smed_4711"
                     /db_xref="GeneID:5318861"
     CDS             complement(1230274..1230933)
                     /locus_tag="Smed_4711"
                     /note="KEGG: sme:SMb21314 putative secreted
                     calcium-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative secreted calcium-binding protein"
                     /protein_id="YP_001313441.1"
                     /db_xref="GI:150376845"
                     /db_xref="InterPro:IPR001343"
                     /db_xref="GeneID:5318861"
                     /translation="MATLEGGAYDDALFGSRFDDFIRAHGGDDFVNGGNGDDIIFGDE
                     GDDLLFGGNGNDTVFGGEGTDVLHGENGNDVLVGGSGDDLIYGDNGDDILLGGAGSDF
                     LLGGRGNDVLLGGAGNDVIDGGSGSDLLAGGQGSDIFVFDGGGGNDVILDFTPGEDVL
                     QISKGINGLDVTAPEDLASRITQVGGNVVIDLGHGDTLTLVNADAEDIQAHPENYFTV
                     H"
     misc_feature    complement(<1230445..>1230705)
                     /locus_tag="Smed_4711"
                     /note="Peptidase M10 serralysin C terminal; Region:
                     Peptidase_M10_C; pfam08548"
                     /db_xref="CDD:117125"
     gene            complement(1231207..1232628)
                     /locus_tag="Smed_4712"
                     /db_xref="GeneID:5318862"
     CDS             complement(1231207..1232628)
                     /locus_tag="Smed_4712"
                     /note="TIGRFAM: type I secretion membrane fusion protein,
                     HlyD family;
                     PFAM: secretion protein HlyD family protein;
                     KEGG: sme:SMb21315 putative protein secretion protein,
                     HlyD family membrane fusion protein, secretes ExpE1"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family type I secretion membrane fusion
                     protein"
                     /protein_id="YP_001313442.1"
                     /db_xref="GI:150376846"
                     /db_xref="InterPro:IPR003997"
                     /db_xref="InterPro:IPR006143"
                     /db_xref="InterPro:IPR010129"
                     /db_xref="GeneID:5318862"
                     /translation="MKTETILPARLDLQPPAETESTERRLPVAAQGRLPMTMPEPDLL
                     ENETRSPIRRLVIAGLTTILVAFGGFFGWAFSTELSSASVTSGTIIVDSKRKTVSHFE
                     GGVLSRILVQEGDHVAPGQPLMQLEDTRARSDLQALESRRVGLIAKLARLRSERSGLQ
                     AVDFPDDLVAAGEAAADAVTAETAFFEKRNEAKEGRIAIQRKTIEEYSEKAKSLTAQL
                     QATDRQIELMNEQRTAIATLVEKAFAQRSKLIEIDARLSELAATRGEIAGDRAQAEKA
                     MAGAELTLTGIESDFQSEIAGEITTARLELAEVEERIISAKDVLRRLEIRAPQAGIVA
                     NIQLRTPGSAVTPGQPLLDIVPEDEPLLVEMHVSTRDIDSITIGSSTQIRLTAYNQRS
                     HLPMDGKVTYIAADQSMDEKSNVAYFVARAEIAPESLAANPDIRLYPGMPAEVLIVHK
                     ARSAIDYLVSPVSDSFNRAFRED"
     misc_feature    complement(1231210..1232472)
                     /locus_tag="Smed_4712"
                     /note="type I secretion membrane fusion protein, HlyD
                     family; Region: type_I_hlyD; TIGR01843"
                     /db_xref="CDD:130902"
     misc_feature    complement(<1232248..1232319)
                     /locus_tag="Smed_4712"
                     /note="Biotinyl_lipoyl_domains are present in
                     biotin-dependent carboxylases/decarboxylases, the
                     dihydrolipoyl acyltransferase component (E2) of 2-oxo acid
                     dehydrogenases, and the H-protein of the glycine cleavage
                     system (GCS). These domains transport CO2, acyl; Region:
                     Biotinyl_lipoyl_domains; cl11404"
                     /db_xref="CDD:245604"
     misc_feature    complement(1231309..1231659)
                     /locus_tag="Smed_4712"
                     /note="HlyD family secretion protein; Region: HlyD_3;
                     pfam13437"
                     /db_xref="CDD:222128"
     gene            complement(1232625..1234394)
                     /locus_tag="Smed_4713"
                     /db_xref="GeneID:5318863"
     CDS             complement(1232625..1234394)
                     /locus_tag="Smed_4713"
                     /note="TIGRFAM: type I secretion system ATPase;
                     PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21316 putative ABC transporter protein, fused
                     ATP-binding and membrane-spanning components, secretes
                     ExpE1"
                     /codon_start=1
                     /transl_table=11
                     /product="type I secretion system ATPase"
                     /protein_id="YP_001313443.1"
                     /db_xref="GI:150376847"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR010128"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="GeneID:5318863"
                     /translation="MRDTVRNPLIGKGHSRSMAPQNGTMAPKLLVLRARRVFVVTLLY
                     AALLSACINLLQLTMPLYMMQVHDRVLNSQSMDTLVMLTILAVGALIVLGVLDFIRAL
                     TFQAMGSAVVRWLNLPVLTAAVQASADQGLARATQSLRDLTELRSFLTSSAVSAPLDA
                     AWSPIFLGVLFLLHPLFGLIGAISVVVLVCCGLLNDLLTRQLMKEASQANIEAVSKIG
                     ATLRHAEAIEAMGMLPALSQKWRAAQLHALSVLEASGIRSRAMASITRSLRFAIQVAA
                     LGTGALLVMRQEISPGAMMATTILVGRLLLPFDSVIENWRQWVLAIASWRRVEAALKE
                     DLAVRQTMPTPRSEGELVVDKLVYAAPGLDVPIIKGINFSLSPGEVLGIVGPSAAGKS
                     TLARLLTGILKPTAGGVFLDGNNVYLWERSSFGQVAGYLPQSVSLLEGTIRENIARMA
                     ESDPYKVLEAARLADVHDMIGRLPLGYDTPVGDGHLTLSGGQRQRIALARCLYGRPRL
                     LVLDEPNANLDAIGERALIRAIEEARRDGAIVILIAHRPAIMQVADKLLVLEGGRISQ
                     FGPRTDVVASMIPGETRREGTAT"
     misc_feature    complement(1232628..1234265)
                     /locus_tag="Smed_4713"
                     /note="ABC-type protease/lipase transport system, ATPase
                     and permease components [General function prediction
                     only]; Region: ArpD; COG4618"
                     /db_xref="CDD:226969"
     misc_feature    complement(1233483..>1233974)
                     /locus_tag="Smed_4713"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:216049"
     misc_feature    complement(1232703..1233344)
                     /locus_tag="Smed_4713"
                     /note="ATP-binding cassette domain of PrtD, subfamily C;
                     Region: ABCC_Protease_Secretion; cd03246"
                     /db_xref="CDD:213213"
     misc_feature    complement(1233219..1233242)
                     /locus_tag="Smed_4713"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213213"
     misc_feature    complement(order(1232760..1232762,1232856..1232861,
                     1233096..1233098,1233216..1233224,1233228..1233233))
                     /locus_tag="Smed_4713"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213213"
     misc_feature    complement(1233096..1233107)
                     /locus_tag="Smed_4713"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213213"
     misc_feature    complement(1232904..1232933)
                     /locus_tag="Smed_4713"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213213"
     misc_feature    complement(1232856..1232873)
                     /locus_tag="Smed_4713"
                     /note="Walker B; other site"
                     /db_xref="CDD:213213"
     misc_feature    complement(1232838..1232849)
                     /locus_tag="Smed_4713"
                     /note="D-loop; other site"
                     /db_xref="CDD:213213"
     misc_feature    complement(1232754..1232774)
                     /locus_tag="Smed_4713"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213213"
     gene            1234615..1235175
                     /locus_tag="Smed_4714"
                     /db_xref="GeneID:5318894"
     CDS             1234615..1235175
                     /locus_tag="Smed_4714"
                     /note="PFAM: regulatory protein MarR;
                     KEGG: sme:SMb21317 transcriptional activator of
                     exopolysaccharide II synthesis, MarR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="YP_001313444.1"
                     /db_xref="GI:150376848"
                     /db_xref="InterPro:IPR000835"
                     /db_xref="GeneID:5318894"
                     /translation="MLYPFADFGDTVSVLPANETMRKGLETLAADQDGDNSLVTYFEL
                     ARVMERASRRFSGLLRAELTKLGVDDIGPAQAMVLLAIGDAELSVGELLDRGHYVGSN
                     ISYYLKQLADGDYIDRIASQRDKRSARIRLSVKGRQVCAGLREAAKGYERALSHGEQD
                     RRNLETAFQTLHRLELVWGNAARYGI"
     misc_feature    1234810..1235085
                     /locus_tag="Smed_4714"
                     /note="helix_turn_helix multiple antibiotic resistance
                     protein; Region: HTH_MARR; smart00347"
                     /db_xref="CDD:197670"
     misc_feature    1234822..1234995
                     /locus_tag="Smed_4714"
                     /note="MarR family; Region: MarR_2; pfam12802"
                     /db_xref="CDD:221778"
     gene            1235316..1236563
                     /locus_tag="Smed_4715"
                     /db_xref="GeneID:5318895"
     CDS             1235316..1236563
                     /locus_tag="Smed_4715"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21318 putative glycosyltransferase, forming
                     alpha-glycosyl linkages protein"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313445.1"
                     /db_xref="GI:150376849"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318895"
                     /translation="MHVAFVHRRGFGQFAALARHLAEAGNEVTLVTETVDQRIPSVRV
                     VRHRAEPGPQPNPHIARHFGVPDHHVRIGHRVAETFDAMRRLGQAPDVILGHIGWGSM
                     MFVKDVLPRVPALGYCEFFYRAEGADVGFAPDDRPDSETRKRLRLRNVAQLLSLEAMD
                     GGISPTNWQRSLYPGDAQQRIAVCHEGIDTRRFRSDPAASLKLPDGRVLKAGDPVVTF
                     VARDLEPYRGFPQALEAAAKVVRRHPDALFVFVGGDGVSYGAPPPGGGSWKDHLLASL
                     DVPRERLIFPGVVPHSVLRQLFQISAAHLYLTYPFVLSWSVLEAMACGALVIGSDTAP
                     VQEVIRSGRNGLLVPFFDPDTLAGTILDVLKGAEGVSAMRRAARRTVEQRFRLDDCLA
                     RQLKLVDNLARRNAALAKETQIT"
     misc_feature    1235316..1236530
                     /locus_tag="Smed_4715"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    1235319..1236500
                     /locus_tag="Smed_4715"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. ExpC in Rhizobium meliloti
                     has been shown to be involved in the biosynthesis of
                     galactoglucan (exopolysaccharide II); Region:
                     GT1_ExpC_like; cd03818"
                     /db_xref="CDD:99988"
     misc_feature    order(1235352..1235354,1235970..1235978,1236195..1236197,
                     1236261..1236263)
                     /locus_tag="Smed_4715"
                     /note="putative ADP-binding pocket [chemical binding];
                     other site"
                     /db_xref="CDD:99988"
     gene            1236732..1238213
                     /locus_tag="Smed_4716"
                     /db_xref="GeneID:5318896"
     CDS             1236732..1238213
                     /locus_tag="Smed_4716"
                     /note="KEGG: sme:SMb21319 putative membrane-anchored
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane-anchored protein"
                     /protein_id="YP_001313446.1"
                     /db_xref="GI:150376850"
                     /db_xref="GeneID:5318896"
                     /translation="MQELMSSSVRQSPTKRRLVVASGLDRENVEGSDIEHLVHFLDPD
                     ASRFPLQNAFPLIALAFSDEGETDLREGLASVHALGTIPEIPLRRIDVPVKAESLSLI
                     RTLVEGGVGRLSRFTSAVTAELAILRRERETLLENYRALEDAFQAHNWEPVAEIFAHD
                     PYADPKDEGIGQLLSTGCVEQLLPVSSHGVAGFALHLHSVPRDGGELVVMLGYVENGE
                     GVAEWTVPYAQLTANWNFFALPRACGGAARTLRLRISTTGTETVELSLGYPIASERYT
                     ARSETPHPDLDLRPLAFRVFTGLPGVKPARMPNMIAPTALLEGHFIEDYRLAVDLLSQ
                     IVDVSVTPVVPEFQTVRFLEHENAVVCHPLPSGISAGTIGRAVEPGTISFSASAIIDH
                     PKGAPAAVSFLLAPANSNARSEVAELARKGAAKPSAFFSGWREVTAAQAININFQLDK
                     PVREPMDLMILSRAVTDTVDFSWLKVSGFRLVKQSAGASNVRQ"
     gene            1238200..1240881
                     /locus_tag="Smed_4717"
                     /db_xref="GeneID:5318897"
     CDS             1238200..1240881
                     /locus_tag="Smed_4717"
                     /note="PFAM: glycosyl transferase family 2; glycosyl
                     transferase group 1;
                     KEGG: sme:SMb21320 putative bifunctional
                     glycosyltransferase, forming beta-glycosyl and
                     alpha-glycosyl linkages protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313447.1"
                     /db_xref="GI:150376851"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318897"
                     /translation="MSGNREDTDLIVVAMPLYGHAALVLEAIESVLASKLSGCSVAVV
                     VSVDGDPRQETFDQLLLYAAAHPAVHVLFGANAGPGGARNRAIEYVLANLPEAEAVYF
                     LDADNRVLPGTIETLYRQLRTSGCGWIYTNIDTFSVSWRAHYGNRYSRLLHCITDNIC
                     DTGSMISLDVFRAGVRFDADRQNGFEDWEFWLSCIEHGFVGEPCHDTTFEYRLRAESR
                     FKEANRDRAASVSFLRKRHRALFQRPMLVDFEHEECPRYLFARTEDAAISYFTDPTKA
                     PKRLRLDDIIPAFWASVGEPDNVHFPPFLIAGSGATLDLLLRSRMLPNVLSHLERLSE
                     KANVVFVQLGNDAAQRKIEPVFLEAGAQHNASPDLIFLSTSLVRDVIQNKALDWFASI
                     GNQQVWPTSAILKVRFPFPRSLPRRLLITPQQVMINCVNAIATSPLRRTAGKRWTWRP
                     ARLVPYSDLHKALRQEVGGSPILPLGHSEGGRKTAALLVPNASFGGAEKVVYAASREL
                     KAAGYETHLFVLGTSRMDVIDEFDQSFDYIHFWDQGIPAWGGSGSFLGHDFIAEGHDV
                     DWAALKGQLSGFDLVINNHVMAVHPLIARLRSEGTRTACYLHVVDNTAFKRPAGQPFA
                     AIAHEHCYDAFLTCSEQLKLYLHSFGVPHEKIFAVPNGASFSVPPKVLSEVLSVRRIE
                     RKDDRLRVLYMGRLDQQKGIDRLAAAIAELRASRVPFDARAVGGEILADATISWTDRL
                     RDLGVEVRSPVFASKDLIKALGWADVLLMPSRWEGAPLMIAEAQQLGCVPIATAVGAV
                     DELITDGEDGILIEAAADPQVVRDMAKAIEEVALNRKQLAPLMEGCLRTAARRSWGSS
                     FSEFLGWCDRSVHNSSLSRATVIRGREASNPGVAAVG"
     misc_feature    1238236..1238802
                     /locus_tag="Smed_4717"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cd00761"
                     /db_xref="CDD:132997"
     misc_feature    order(1238245..1238247,1238251..1238253,1238335..1238337,
                     1238509..1238511,1238515..1238517)
                     /locus_tag="Smed_4717"
                     /note="active site"
                     /db_xref="CDD:132997"
     misc_feature    1239664..1240758
                     /locus_tag="Smed_4717"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    1239676..1240758
                     /locus_tag="Smed_4717"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases and named after YqgM in
                     Bacillus licheniformis about which little is known.
                     Glycosyltransferases catalyze the transfer of sugar
                     moieties from activated donor molecules to...; Region:
                     GT1_YqgM_like; cd03801"
                     /db_xref="CDD:99974"
     gene            1240917..1242095
                     /locus_tag="Smed_4718"
                     /db_xref="GeneID:5318898"
     CDS             1240917..1242095
                     /locus_tag="Smed_4718"
                     /note="PFAM: polysaccharide pyruvyl transferase;
                     KEGG: sme:SMb21321 putative membrane-anchored protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase"
                     /protein_id="YP_001313448.1"
                     /db_xref="GI:150376852"
                     /db_xref="InterPro:IPR007345"
                     /db_xref="GeneID:5318898"
                     /translation="MRPRILVTGIPGHYTRLANGAQGLSVSYSERQKQPETKEEFLQE
                     LRNISNTGNYLIGEGALRAIAPHAKQVPFWHLYNCSQNGVGLEEFNANFDICVFTCAN
                     LLRKGLSADAEAEVLGKLKMPIVMLGIGLQNRRDLENSLPEGTKRLLDVLKEREHYFL
                     TRGFETAGFLKDQGFSYVQPTGCPSIYLMPHNMRASLKKLPKVPVGKARTIFSGYLGA
                     NHDCIVDAAALAPEGSRPQYVIQDEFLHFDMNVEANGDGRVYDSASGVMLGELSYPGT
                     ERLKTPFDVRTFFDTNQWRAWASSMDFNFGRRFHGSIIAMQAAVPSLMVAVDDRMREM
                     LGYTGLPAIDAVEVDKADNRAEFVADHLAGLNASELVDRYSDRERTFRSALREIGIGQ
                     "
     misc_feature    1241064..1241588
                     /locus_tag="Smed_4718"
                     /note="Polysaccharide pyruvyl transferase; Region:
                     PS_pyruv_trans; cl09156"
                     /db_xref="CDD:245023"
     misc_feature    <1241748..1241903
                     /locus_tag="Smed_4718"
                     /note="Polysaccharide pyruvyl transferase; Region:
                     PS_pyruv_trans; pfam04230"
                     /db_xref="CDD:217977"
     gene            1242136..1243308
                     /locus_tag="Smed_4719"
                     /db_xref="GeneID:5318899"
     CDS             1242136..1243308
                     /locus_tag="Smed_4719"
                     /note="PFAM: polysaccharide pyruvyl transferase;
                     KEGG: sme:SMb21322 putative membrane-anchored protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase"
                     /protein_id="YP_001313449.1"
                     /db_xref="GI:150376853"
                     /db_xref="InterPro:IPR007345"
                     /db_xref="GeneID:5318899"
                     /translation="MRILLTGIPSYLQRTVSGVNGAEVRHRPYFDEVRTKKELIDQVK
                     KIANTGNYLIGEGAAHALRGHDVTYLPFWHLVNSRNSDEVYERLNEEFDICVFASANL
                     LRPGYSADLEAEVFQKLNMPVVIMGIGIQRREGLKENLPPGTLKFLEVLKKKESFFLT
                     RGYFTAEFLREQGMKFVKPTGCPSLFFAPVEMKRSLTALANPELASSQKIAFGGYLGS
                     VADTIVDAHALLKPESVASYVIQDEVVAYNLSLPVDDDLPVYDRASGRITGDTAYKHS
                     EKWQRKHELLVFFDTNQWRSWVSTRDLCFGRRFHGCIIGMQAGVPSLMIAVDDRMREM
                     LEFIGFPYMEAAIWNREADRKAYLSSFLSKIDSQAVIDRYSACETNFRNALAHVGL"
     misc_feature    1242277..1242768
                     /locus_tag="Smed_4719"
                     /note="Polysaccharide pyruvyl transferase; Region:
                     PS_pyruv_trans; pfam04230"
                     /db_xref="CDD:217977"
     misc_feature    <1242931..1243122
                     /locus_tag="Smed_4719"
                     /note="Polysaccharide pyruvyl transferase; Region:
                     PS_pyruv_trans; pfam04230"
                     /db_xref="CDD:217977"
     gene            1243283..1244467
                     /locus_tag="Smed_4720"
                     /db_xref="GeneID:5318900"
     CDS             1243283..1244467
                     /locus_tag="Smed_4720"
                     /note="KEGG: sme:SMb21323 putative protein, probably
                     exported to periplasma"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313450.1"
                     /db_xref="GI:150376854"
                     /db_xref="GeneID:5318900"
                     /translation="MLWLMSGSRAIPGKVRSGFPSGIAQKHRAGALLLTALLALTAPA
                     HAGEVPAVRIGINRMNLAWLPRSEQEKVLKDIAMSGATDIRLSLSRPIDESIEALAIA
                     HRLGLRILLEIQLGNKSYYPQSAGPRTGHGRIWDVYRLSDLDLARYRRELHDALRRID
                     ALGIRLEAIEPGNEINYAGYNGDLAVFRKPGTRTPRSLGELQDRAGFERGLDNYVQAV
                     AITRSEVRRTTHSRDAAVISAGLSDMSAAEADRRGMERLDPHQLVALLQERGIDSLVD
                     AYGIHIYPGRKAAPAIAARVRSLLEFCQPAATGRSCWVTEWGIANTARSCPVDDRSRG
                     KAIGATRAAFGEFIEAGRLTAAYYYDWDSEPSYSLWRCGKLSPDAATALSPLESAGAR
                     AR"
     sig_peptide     1243283..1243423
                     /locus_tag="Smed_4720"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 47"
     gene            1244464..1245372
                     /locus_tag="Smed_4721"
                     /db_xref="GeneID:5318901"
     CDS             1244464..1245372
                     /locus_tag="Smed_4721"
                     /note="TIGRFAM: glucose-1-phosphate thymidylyltransferase;
                     PFAM: Nucleotidyl transferase;
                     KEGG: sme:SMb21324 putative glucose-1-phosphate
                     thymidyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="YP_001313451.1"
                     /db_xref="GI:150376855"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="GeneID:5318901"
                     /translation="MMSASEGNPMRGIILAGGRGTRLYPVTISVSKQLLPVHDKPMIY
                     YPLGTLMLAGIREILVITMPRDRPLFEELLGDGSQFGLAISYAEQPEPNGLAEAFVIG
                     RDFIGDSAVALILGDNIFYGAGLPELCSAATARASGATIFAYRVDDPERYGVVSFDGN
                     TGRAETIEEKPARARSSWAVTGLYFYENSVVEIASSIKPSARGELEITDVNRAYLERG
                     DLHVCRLGRGFAWLDTGTHQSLHDAASFVRAIEHRQGVKIMCPEEIAFELGYVSADQV
                     LERADLLGKNDYAFYLQRRIRELADA"
     misc_feature    1244491..1245213
                     /locus_tag="Smed_4721"
                     /note="G1P_TT_short is the short form of
                     glucose-1-phosphate thymidylyltransferase; Region:
                     G1P_TT_short; cd02538"
                     /db_xref="CDD:133019"
     misc_feature    1244494..1245345
                     /locus_tag="Smed_4721"
                     /note="glucose-1-phosphate thymidylyltransferase, short
                     form; Region: rmlA; TIGR01207"
                     /db_xref="CDD:130274"
     misc_feature    order(1244506..1244508,1244512..1244517,1244728..1244730,
                     1244737..1244748,1244812..1244814,1244920..1244922,
                     1244968..1244973,1245001..1245003,1245085..1245087)
                     /locus_tag="Smed_4721"
                     /note="substrate binding site; other site"
                     /db_xref="CDD:133019"
     misc_feature    order(1244524..1244526,1244533..1244541,1244548..1244553,
                     1244563..1244571,1244575..1244586,1244593..1244595,
                     1244668..1244670,1244824..1244829,1244893..1244904,
                     1244914..1244919,1245154..1245162,1245172..1245177,
                     1245184..1245186,1245193..1245201,1245208..1245213)
                     /locus_tag="Smed_4721"
                     /note="tetramer interface; other site"
                     /db_xref="CDD:133019"
     gene            1245365..1245928
                     /locus_tag="Smed_4722"
                     /db_xref="GeneID:5318902"
     CDS             1245365..1245928
                     /locus_tag="Smed_4722"
                     /EC_number="5.1.3.13"
                     /note="TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase;
                     PFAM: dTDP-4-dehydrorhamnose 35-epimerase related;
                     KEGG: sme:SMb21325 putative dTDP-4-dehydrorhamnose
                     3,5-epimerase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="YP_001313452.1"
                     /db_xref="GI:150376856"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="GeneID:5318902"
                     /translation="MLEVRPLSLGGVLEIVPRKFGDERGFFSETFNAETLAAQGVELS
                     FVQDNHSYSALAGTLRGLHYQLPPKAQAKLVRVVRGRVFDVVVDIRKGSPSFAKWLGL
                     ELSAERWNQILVPAGFAHGFVTLEPETEVLYKVTEHYSAEHERSIRFDDPAIGIGWPV
                     AADRLQLSAKDRNAALLNESNLFEFTA"
     misc_feature    1245374..1245901
                     /locus_tag="Smed_4722"
                     /note="dTDP-4-dehydrorhamnose 3,5-epimerase; Region:
                     dTDP_sugar_isom; pfam00908"
                     /db_xref="CDD:144487"
     gene            1245940..1247010
                     /locus_tag="Smed_4723"
                     /db_xref="GeneID:5318903"
     CDS             1245940..1247010
                     /locus_tag="Smed_4723"
                     /note="TIGRFAM: dTDP-glucose 4,6-dehydratase;
                     PFAM: NAD-dependent epimerase/dehydratase; short-chain
                     dehydrogenase/reductase SDR; 3-beta hydroxysteroid
                     dehydrogenase/isomerase; polysaccharide biosynthesis
                     protein CapD; dTDP-4-dehydrorhamnose reductase; Male
                     sterility domain;
                     KEGG: sme:SMb21326 putative dTDP-D-glucose 4,6-dehydratase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="YP_001313453.1"
                     /db_xref="GI:150376857"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318903"
                     /translation="MRVLVTGGAGFIGSAVCRHLIRCGAERVVNVDKLTYAGSLASLR
                     AVEGDPRYAFYRADILDEKVLLQIMRRERVDAIMHLAAESHVDRSIEGPDLFMETNVL
                     GTVRLLNAALAYWSGLGLEGQERFRFHHVSTDEVFGDLPFNRGIFSEESRYAPSSPYA
                     ASKAAADHFARAWHRTYGLPVVVSNCSNNYGPFHFPEKLIPLTIINAIEEEPLPLYGS
                     GANVRDWLHVDDHAAALDLVISQGRPGESYNIGARAERNNLSVMESICDLIDMKLPRK
                     GGGSYRDLITLVPDRPGHDRRYAIDPSKVERELGWRPKRSFEAGLSETVDWFLANRWW
                     WEPIRRERHSGSRIGGLHRSVA"
     misc_feature    1245940..1246995
                     /locus_tag="Smed_4723"
                     /note="dTDP-D-glucose 4,6-dehydratase [Cell envelope
                     biogenesis, outer membrane]; Region: RfbB; COG1088"
                     /db_xref="CDD:224013"
     misc_feature    1245940..1246938
                     /locus_tag="Smed_4723"
                     /note="dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs;
                     Region: dTDP_GD_SDR_e; cd05246"
                     /db_xref="CDD:187557"
     misc_feature    order(1245958..1245960,1245964..1245975,1246033..1246044,
                     1246048..1246053,1246108..1246116,1246177..1246185,
                     1246189..1246191,1246234..1246236,1246330..1246338,
                     1246414..1246416,1246426..1246428,1246495..1246506)
                     /locus_tag="Smed_4723"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187557"
     misc_feature    order(1246189..1246197,1246336..1246344,1246414..1246416,
                     1246495..1246503,1246528..1246536,1246543..1246548,
                     1246579..1246587,1246600..1246602,1246606..1246608,
                     1246711..1246713,1246810..1246812,1246819..1246821,
                     1246831..1246833)
                     /locus_tag="Smed_4723"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187557"
     misc_feature    order(1246201..1246203,1246207..1246209,1246216..1246221,
                     1246228..1246230,1246240..1246245,1246252..1246254,
                     1246264..1246266,1246273..1246275,1246354..1246356,
                     1246387..1246389,1246393..1246398,1246402..1246413,
                     1246420..1246422,1246429..1246434,1246441..1246446,
                     1246453..1246458,1246462..1246470,1246822..1246824)
                     /locus_tag="Smed_4723"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187557"
     misc_feature    order(1246237..1246239,1246336..1246338,1246414..1246416,
                     1246426..1246428)
                     /locus_tag="Smed_4723"
                     /note="active site"
                     /db_xref="CDD:187557"
     gene            1247007..1247909
                     /locus_tag="Smed_4724"
                     /db_xref="GeneID:5318904"
     CDS             1247007..1247909
                     /locus_tag="Smed_4724"
                     /EC_number="1.1.1.133"
                     /note="PFAM: NAD-dependent epimerase/dehydratase;
                     polysaccharide biosynthesis protein CapD;
                     dTDP-4-dehydrorhamnose reductase; Male sterility domain;
                     KEGG: sme:SMb21327 putative dTDP-4-dehydrorhamnose
                     reductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="YP_001313454.1"
                     /db_xref="GI:150376858"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318904"
                     /translation="MRIVVTGCKGQLARSLLEQARGLPGTEVILIGRPQLDLTDPPTI
                     LAAIEPHRPDLVVSAAAFTAVDQAEGEPETAFAVNAFGAEAVAGAAASLGAPVLHVST
                     DYVFDGSKHGSYAEDDMPAPVSVYGASKLAGELAVAEANPRHVILRTGWVYSPFGKNF
                     IKTILRLAGEREEIAVVADQWGNPTSALDLADAILGISAQLTRCGRDFVFGLYHLAGA
                     GTTSRADLARHALSASRAEGGPWAHVRDVATSAFPTPARRPTNSSLSSAKFTAAFRWS
                     MPPWQYSVECTVRRLVQSTSSETI"
     misc_feature    1247010..1247849
                     /locus_tag="Smed_4724"
                     /note="dTDP-6-deoxy-L-lyxo-4-hexulose reductase and
                     related proteins, extended (e) SDRs; Region:
                     dTDP_HR_like_SDR_e; cd05254"
                     /db_xref="CDD:187564"
     misc_feature    1247013..1247882
                     /locus_tag="Smed_4724"
                     /note="RmlD substrate binding domain; Region:
                     RmlD_sub_bind; pfam04321"
                     /db_xref="CDD:218026"
     misc_feature    order(1247025..1247027,1247031..1247042,1247100..1247105,
                     1247112..1247123,1247181..1247189,1247193..1247195,
                     1247238..1247240,1247304..1247312,1247382..1247384,
                     1247394..1247396,1247451..1247462)
                     /locus_tag="Smed_4724"
                     /note="NADP binding site [chemical binding]; other site"
                     /db_xref="CDD:187564"
     misc_feature    order(1247241..1247243,1247310..1247312,1247382..1247384,
                     1247394..1247396)
                     /locus_tag="Smed_4724"
                     /note="active site"
                     /db_xref="CDD:187564"
     misc_feature    order(1247310..1247312,1247382..1247384,1247457..1247459,
                     1247496..1247498,1247532..1247534,1247550..1247552)
                     /locus_tag="Smed_4724"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187564"
     gene            complement(1247906..1248724)
                     /locus_tag="Smed_4725"
                     /db_xref="GeneID:5319071"
     CDS             complement(1247906..1248724)
                     /locus_tag="Smed_4725"
                     /note="KEGG: sme:SMb21328 putative Sir2-like
                     transcriptional silencer protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative Sir2-like transcriptional silencer
                     protein"
                     /protein_id="YP_001313455.1"
                     /db_xref="GI:150376859"
                     /db_xref="GeneID:5319071"
                     /translation="MKEHIQQIVSALKRRHAVLFVGAGVSMSVGLPSWKTLVDHMLSE
                     LRLDESVMRDPDISYQTIAECYRLEHGNIASLCEWMRHNWRISPERIKRSELHRLIVE
                     LDFPVIYTTNYDSNLESAYDVYGKRYAKISHVRDIASAPAGVTRIIKYHGDFDDDDTL
                     ILTETDYFNRLSFESPLDVRFRSDALEATVLFVGYSMSDLNIRLLLHRIWSTWQRSGH
                     EKDRPASYVFMYRPNPVQKAVLGKWGVTVLAGEGDDPQQSLLAFTRSLRTELGG"
     misc_feature    complement(1247969..1248679)
                     /locus_tag="Smed_4725"
                     /note="Sir2-like: Prokaryotic group of uncharacterized
                     Sir2-like proteins which lack certain key catalytic
                     residues and conserved zinc binding cysteines; and are
                     members of the SIR2 superfamily of proteins, silent
                     information regulator 2 (Sir2) enzymes which...; Region:
                     SIR2-like; cd01406"
                     /db_xref="CDD:238697"
     gene            complement(1248797..1248967)
                     /locus_tag="Smed_4726"
                     /db_xref="GeneID:5319072"
     CDS             complement(1248797..1248967)
                     /locus_tag="Smed_4726"
                     /note="KEGG: sme:SMb21329 hypothetical exported peptide
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313456.1"
                     /db_xref="GI:150376860"
                     /db_xref="GeneID:5319072"
                     /translation="MVHDRDKRRKRRRHVLRFFSALALPALLLGSAIAAAEWATPDPP
                     VRADAPKAGNRR"
     sig_peptide     complement(1248857..1248967)
                     /locus_tag="Smed_4726"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.909 at
                     residue 37"
     gene            1249182..1249391
                     /locus_tag="Smed_4727"
                     /db_xref="GeneID:5319073"
     CDS             1249182..1249391
                     /locus_tag="Smed_4727"
                     /note="PFAM: CsbD family protein;
                     KEGG: sme:SMb21330 hypothetical protein with amino acid
                     permeases signature"
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="YP_001313457.1"
                     /db_xref="GI:150376861"
                     /db_xref="InterPro:IPR008462"
                     /db_xref="GeneID:5319073"
                     /translation="MDWNRVEGNWKQVKGRIKEQWGKLTDDDLDQISGNRDQLEGKIQ
                     ERYGIEKDRVRRDLDDWYGRQTWDW"
     misc_feature    1249182..1249376
                     /locus_tag="Smed_4727"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3237"
                     /db_xref="CDD:225777"
     gene            1249462..1249959
                     /locus_tag="Smed_4728"
                     /db_xref="GeneID:5319074"
     CDS             1249462..1249959
                     /locus_tag="Smed_4728"
                     /note="PFAM: transport-associated;
                     SMART: Transport-associated and nodulation region;
                     KEGG: sme:SMb21332 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transport-associated protein"
                     /protein_id="YP_001313458.1"
                     /db_xref="GI:150376862"
                     /db_xref="InterPro:IPR007055"
                     /db_xref="InterPro:IPR014004"
                     /db_xref="GeneID:5319074"
                     /translation="MKVPHKEKALSRDEDYRDYEERDLREGWPYSDGSGSTSRSPENG
                     SYGSTGANFDEERGEGFIVDDAGADGLEENPVDNGRSLPTNRIDSDELEAVITDRLTQ
                     NDETEANGIEVRAVNGIVTLEGAVETLERARRIQAVVEAVAGVLEVRNNLQTLGVDSH
                     IPDDG"
     gene            1249996..1250367
                     /locus_tag="Smed_4729"
                     /db_xref="GeneID:5319075"
     CDS             1249996..1250367
                     /locus_tag="Smed_4729"
                     /note="KEGG: sme:SMb21333 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313459.1"
                     /db_xref="GI:150376863"
                     /db_xref="GeneID:5319075"
                     /translation="MEEPMAIFEVLADPELAQELGVAVAMLTRDEGRDRPRKGIMLTR
                     ELVEDAFEGDRERAAEAARSGLIDQEAMRRIDSPDRLTYQPRGQAGQAAWVLAAFTRD
                     DLGLFEGPVRSGGAGAGGITA"
     gene            1250559..1251248
                     /locus_tag="Smed_4730"
                     /db_xref="GeneID:5319076"
     CDS             1250559..1251248
                     /locus_tag="Smed_4730"
                     /note="PFAM: protein of unknown function DUF1236;
                     KEGG: sme:SMb21334 hypothetical exported glutamine-rich
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313460.1"
                     /db_xref="GI:150376864"
                     /db_xref="InterPro:IPR009642"
                     /db_xref="GeneID:5319076"
                     /translation="MKGILIRSAIAVSLGVASTPVLSQTEQPAQGQSSGQSTDCPAGT
                     ECPQGGTQPDQQPDPQGGATQQGQTGQDQQQQPADQQQDQQGQSDTKQDQGGTQTQEQ
                     GSDAQTQQQDSEQQPSQGGTDQPAQGESRSTEQGQTSGSSGNVDVTIEQKTEITQVIK
                     EENVDPIDVDFDVSVGVAVPETVKVELQPVPTRIVQIVPEYEGYLFFVLADGRIVIVE
                     PSSLEIVVILS"
     sig_peptide     1250559..1250630
                     /locus_tag="Smed_4730"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.986 at
                     residue 24"
     misc_feature    1251030..1251242
                     /locus_tag="Smed_4730"
                     /note="Protein of unknown function (DUF1236); Region:
                     DUF1236; pfam06823"
                     /db_xref="CDD:219192"
     gene            complement(1251363..1252442)
                     /locus_tag="Smed_4731"
                     /db_xref="GeneID:5319077"
     CDS             complement(1251363..1252442)
                     /locus_tag="Smed_4731"
                     /note="PFAM: protein of unknown function UPF0118;
                     KEGG: sme:SMb21335 conserved putative membrane protein,
                     possibly a permease"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313461.1"
                     /db_xref="GI:150376865"
                     /db_xref="InterPro:IPR002549"
                     /db_xref="GeneID:5319077"
                     /translation="MAKSIPVRDEDENSNRLFTPRRSRTLAVLVALLVGLVVCTFLTV
                     PFLPALTWALVLAVMFQPLHRRVKSRFRYPDAAAAATVAIAVFVVAVPLTFMAERLVN
                     EAAKGAKIIEEALRSGTWRDALANYPRLAPAVVWIETQLDLAGIAGSATSWLTNFSAS
                     FVRGSVAQIIDAVLTFYFLFYFMRDGRQVLAALKEHSPLSEQDMNRLFTRVHETVHAV
                     VFGTVAVAAVQGAMGGLMFWLLGLPAPVVWGLAMGLLAVVPVLGAFIVWLPAALSLAL
                     SGEWGKALILAGWGAGVVATIDNLLYPIFVGDRLKLHTLTAFMSMIGGIIVFGSAGLV
                     IGPVAFTVTLLLLDIWRQHNTEPRA"
     misc_feature    complement(1251390..1252328)
                     /locus_tag="Smed_4731"
                     /note="Domain of unknown function DUF20; Region: UPF0118;
                     pfam01594"
                     /db_xref="CDD:216594"
     misc_feature    complement(1251369..1252310)
                     /locus_tag="Smed_4731"
                     /note="Predicted permease, member of the PurR regulon
                     [General function prediction only]; Region: yhhT; COG0628"
                     /db_xref="CDD:223701"
     gene            1252737..1253618
                     /locus_tag="Smed_4732"
                     /db_xref="GeneID:5319078"
     CDS             1252737..1253618
                     /locus_tag="Smed_4732"
                     /note="PFAM: helix-turn-helix- domain containing protein
                     AraC type;
                     KEGG: sme:SMb21336 putative transcriptional regulator,
                     AraC family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="YP_001313462.1"
                     /db_xref="GI:150376866"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="GeneID:5319078"
                     /translation="MSFRPLLGNGRIRTAGERLAKPLTASWANSSIIFDRRRWACREA
                     EMRWTAPHHLFVLTERGGTSQTLIRSDGSLYQGRDGPGALTFVPAGTERLGAYRDVDL
                     TYSALWIDPRSIPPGSDHLKNLPVLINKSDFVTEALLKSLSCEISRGHAPDTAYMEHL
                     VALIALRIRSVFDEPVKVIRHGSLGGAVVKRVRDYIDAHLDGDISLGELAHVAGVAAD
                     SFARRFKATTGLAPYAYVIEERVRRAESLLHETDIALSEIALNCGFSSQSHFTATFKR
                     LRGITPRAYRSDVIPEF"
     misc_feature    1253343..1253594
                     /locus_tag="Smed_4732"
                     /note="helix_turn_helix, arabinose operon control protein;
                     Region: HTH_ARAC; smart00342"
                     /db_xref="CDD:197666"
     misc_feature    1253484..1253594
                     /locus_tag="Smed_4732"
                     /note="Bacterial regulatory helix-turn-helix proteins,
                     AraC family; Region: HTH_AraC; pfam00165"
                     /db_xref="CDD:215763"
     gene            1253745..1254404
                     /locus_tag="Smed_4733"
                     /db_xref="GeneID:5319079"
     CDS             1253745..1254404
                     /locus_tag="Smed_4733"
                     /note="PFAM: ferredoxin; [2Fe-2S]-binding domain protein;
                     KEGG: sme:SMb21337 putative iron-sulfur-binding protein,
                     probably subunit of an oxidoreductase like aldehyde
                     oxidase or xanthine dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="YP_001313463.1"
                     /db_xref="GI:150376867"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR002086"
                     /db_xref="InterPro:IPR002888"
                     /db_xref="InterPro:IPR006058"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5319079"
                     /translation="MPEKQKETGPTRRALLEGGAATTMLLVAGLPVGRSAVAAVAAEP
                     TVTPMPTLPVMLNINARNIAVEVDPRTTLLDTLRNHLGLTGSKKGCDHGQCGACTVLV
                     NGRRINACLSLAAMHEGDEITTIEGLAAGGELHPVQAAFIEHDGFQCGYCTPGQICSA
                     VAMLREAKDGWPSHVSADVGAAPAALTDTEIRERMSGNLCRCAAYPNIIAAIRDAAER
                     S"
     sig_peptide     1253745..1253870
                     /locus_tag="Smed_4733"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.764) with cleavage site probability 0.378 at
                     residue 42"
     misc_feature    1253775..1254398
                     /locus_tag="Smed_4733"
                     /note="aldehyde oxidoreductase 2Fe-2S subunit;
                     Provisional; Region: PRK11433"
                     /db_xref="CDD:236910"
     misc_feature    1253913..1254089
                     /locus_tag="Smed_4733"
                     /note="2Fe-2S iron-sulfur cluster binding domain.
                     Iron-sulfur proteins play an important role in electron
                     transfer processes and in various enzymatic reactions. The
                     family includes plant and algal ferredoxins, which act as
                     electron carriers in photosynthesis...; Region: fer2;
                     cd00207"
                     /db_xref="CDD:238126"
     misc_feature    order(1253997..1253999,1254003..1254005,1254012..1254014,
                     1254021..1254023,1254027..1254038,1254069..1254074)
                     /locus_tag="Smed_4733"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     misc_feature    order(1254012..1254014,1254027..1254029,1254036..1254038,
                     1254072..1254074)
                     /locus_tag="Smed_4733"
                     /note="iron binding site [ion binding]; other site"
                     /db_xref="CDD:238126"
     misc_feature    1254114..1254386
                     /locus_tag="Smed_4733"
                     /note="[2Fe-2S] binding domain; Region: Fer2_2; pfam01799"
                     /db_xref="CDD:201981"
     gene            1254408..1255394
                     /locus_tag="Smed_4734"
                     /db_xref="GeneID:5319080"
     CDS             1254408..1255394
                     /locus_tag="Smed_4734"
                     /note="PFAM: molybdopterin dehydrogenase FAD-binding; CO
                     dehydrogenase flavoprotein domain protein;
                     KEGG: sme:SMb21338 putative molybdopterin binding protein,
                     probably subunit of an oxidoreductase like aldehyde
                     oxidase or xanthine dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding molybdopterin dehydrogenase"
                     /protein_id="YP_001313464.1"
                     /db_xref="GI:150376868"
                     /db_xref="InterPro:IPR002346"
                     /db_xref="InterPro:IPR005107"
                     /db_xref="GeneID:5319080"
                     /translation="MQPFTYQRSEDAAGAVAAVAGRPAARFISGGTNLLDLMKLDIER
                     PQHLVDISRLPLDRVEPTEEGGLHIGAQVRNSDLAADPGVRSRYPILSQALLAGASGQ
                     IRNKASTGGNLLQRTRCPYFYDSNMPCNKREPGAGCAALRGFNRMHAVIGASDSCIAV
                     HPSDMAVAMAVLDARVETVSPGGETRSIPLGDLYLLPGTTADEETVLAHGEMITGVTL
                     PPPPAGRQVYRKVRDRASYAFALVSVAAIIETSGNRVRSARVAMGGVAPKPWRAPEVE
                     SRLAGSALSDQALSEAAEAALPEAVGHGGNDFKIRLAKRTVRYTLAAAAELV"
     misc_feature    1254408..1255385
                     /locus_tag="Smed_4734"
                     /note="Aerobic-type carbon monoxide dehydrogenase, middle
                     subunit CoxM/CutM homologs [Energy production and
                     conversion]; Region: CoxM; COG1319"
                     /db_xref="CDD:224238"
     misc_feature    1255089..1255379
                     /locus_tag="Smed_4734"
                     /note="CO dehydrogenase flavoprotein C-terminal domain;
                     Region: CO_deh_flav_C; smart01092"
                     /db_xref="CDD:215021"
     gene            1255417..1257693
                     /locus_tag="Smed_4735"
                     /db_xref="GeneID:5319081"
     CDS             1255417..1257693
                     /locus_tag="Smed_4735"
                     /note="PFAM: aldehyde oxidase and xanthine dehydrogenase
                     a/b hammerhead; aldehyde oxidase and xanthine
                     dehydrogenase molybdopterin binding;
                     KEGG: xcb:XC_3780 oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidase and xanthine dehydrogenase
                     molybdopterin binding protein"
                     /protein_id="YP_001313465.1"
                     /db_xref="GI:150376869"
                     /db_xref="InterPro:IPR000674"
                     /db_xref="InterPro:IPR008274"
                     /db_xref="GeneID:5319081"
                     /translation="MTENAQRRPTSGGDQFIGKAVDRVDGPRKVTGTAPYAYEIAEGP
                     LPAYGYILGAAIAKGRILEIDAELAERAPGVLYVMTHLNAPRQPEFGPAVTPAVREVF
                     TRARPVLRGDHVHYYDQPIGLVVAETFEAARAAAALIKIRYQETAGDFGLEEHLAAAY
                     APKRTNAGFETDSAVGDFEAAFAEAEVRIDVSYRTPYQHHNPMEPHATLAIWQGDDVT
                     IHTSAQTLSNFRAGLAATLGVPVERVRVVSRYIGGGFGSKLIVHADSVFAALAARILK
                     RPVKITLTRQQMFANAGHRAEMLQQVRLGARADGRLIALGHDVWSATARVEEFCEQTA
                     VFARSLYAASNRLTRHRLVTVDLNRGEWMRSPGEAPGMLALECAMDELAEHLDLDPIE
                     LRIRNEPDQDPERRVPFSTRNLVACMQEGARRFDWGRRSPEPGRLREGRKLVGMGMAA
                     AIRPNYIGAAAAWVRIDAEGQVTARLDMTDIGTGTYTILTQIAADTLGVPLAAIAIEL
                     GDSRFPLTAGSGGSWGAASAGTALLRACEALKEKILAAARVHGAPVRNAADVSMAAGA
                     VRFGNRAEDLKDVLRRVAPEGLDARGSVEAGAGTEAYQAFSQHSYGAHFAEVSVDCDT
                     GEIRARRLLAVIDAGRILNTKTARSQILGGMTWGLGAALMEKTVLDGRYGHFVNHDLA
                     EYHIPVNGDVPDLDVVFLEENDDKANPLGAKGLGELGVCGAGAAIANAVYNATGVRVR
                     EFPLTLDKLLPGLPAFVL"
     misc_feature    1255465..1257681
                     /locus_tag="Smed_4735"
                     /note="Aerobic-type carbon monoxide dehydrogenase, large
                     subunit CoxL/CutL homologs [Energy production and
                     conversion]; Region: CoxL; COG1529"
                     /db_xref="CDD:224446"
     misc_feature    1255507..1255851
                     /locus_tag="Smed_4735"
                     /note="Aldehyde oxidase and xanthine dehydrogenase, a/b
                     hammerhead domain; Region: Ald_Xan_dh_C; smart01008"
                     /db_xref="CDD:214971"
     misc_feature    1255912..1257495
                     /locus_tag="Smed_4735"
                     /note="Molybdopterin-binding domain of aldehyde
                     dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738"
                     /db_xref="CDD:217210"
     gene            complement(1257810..1258658)
                     /locus_tag="Smed_4736"
                     /db_xref="GeneID:5319104"
     CDS             complement(1257810..1258658)
                     /locus_tag="Smed_4736"
                     /note="PFAM: Phytanoyl-CoA dioxygenase;
                     KEGG: sme:SMb21341 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phytanoyl-CoA dioxygenase"
                     /protein_id="YP_001313466.1"
                     /db_xref="GI:150376870"
                     /db_xref="InterPro:IPR008775"
                     /db_xref="GeneID:5319104"
                     /translation="MNTTATRETSPGYDLDASVEALQREGITGLKSAFSREWAEAMRE
                     DMMTAFWSAIQRPGGAVGRGPRRWYVEIHPQDFSGFVDLVTHPWVVGICEAMLGPDYQ
                     IVEIGFDVPFQGAKYQPWHRDFPSPPETYVERRITSLAFNLTGVDVTEDMGPFEIAPG
                     TQWLDGREWKHEMFPPKERWPEFQKLATRKYPRLGDVSCRSALTIHRGTEHASPIARP
                     VMVLGVDAPGAGHAELHDMMVTQDYYDALPKLVKQHLVCRIVDELIPVTQKHDIEGLV
                     MGSTPT"
     misc_feature    complement(1258020..>1258442)
                     /locus_tag="Smed_4736"
                     /note="Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH;
                     cl17312"
                     /db_xref="CDD:247866"
     gene            complement(1258704..1259696)
                     /locus_tag="Smed_4737"
                     /db_xref="GeneID:5319105"
     CDS             complement(1258704..1259696)
                     /locus_tag="Smed_4737"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb21342 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001313467.1"
                     /db_xref="GI:150376871"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5319105"
                     /translation="MNAFRNTFALKSSGDMARLGVILALAGLILFGALRYENFLSQYN
                     ILSFLRYNSMFALIALGMAFVIMTGGIDLSVGGTAAMASVVAALLSPYHWAAGLFGGI
                     AAGLAVGALNGFTVTVMRIQPFIATLATMLAAYGTALLLAGNQSVSVSYDSGFTAIGQ
                     DDFLGFPIPAWIALLVYFAGWLVLERLPVGRHVLAIGDGEATAALMGLKVRRTLAAVY
                     IGSGALAGLAGVILASQFGAGQPTEGVGWELFAIASVVVGGTLLTGGSGSVGATLAGA
                     LLLAMVFNILNFENGLGWISLSAYWQSVIRGGFLLVVVVLQARLMSRGASEGRV"
     misc_feature    complement(1258941..1259567)
                     /locus_tag="Smed_4737"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(1258746..1259543)
                     /locus_tag="Smed_4737"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(1259040..1259096)
                     /locus_tag="Smed_4737"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(1259709..1260713)
                     /locus_tag="Smed_4738"
                     /db_xref="GeneID:5319106"
     CDS             complement(1259709..1260713)
                     /locus_tag="Smed_4738"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb21343 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001313468.1"
                     /db_xref="GI:150376872"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5319106"
                     /translation="MTTIETQATAGTVPSGKRFFTLAGRYGTVAAFLALILFNVLFTP
                     NFLSLQTLNVNLTQVATIVIVATGMTLVIATGGIDLSVGSLMAIGGALAPMIFMGALF
                     PVSSMPVAVALAFILPVIATALLGLFNGLLVTRFAIQPIIATLVLFIAGRGIAQVMTN
                     GNLQVFRNEGFQFIALGRIAGIPAQVILMIVIAAIAWAAVRHTVFGRQVIAVGGNEKA
                     ARLTGIPVHRVKLLVYMISGALAGVAGLIVVARNSASDANLVGLGMELDAIAAVAVGG
                     TLLTGGRANIMGTLIGALVIQLVRYTLLANGVPDAAALIVKAALILLAVFIQQRAGKP
                     "
     misc_feature    complement(1259817..1260548)
                     /locus_tag="Smed_4738"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(1259787..1260539)
                     /locus_tag="Smed_4738"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(1260009..1260065)
                     /locus_tag="Smed_4738"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(1260715..1262208)
                     /locus_tag="Smed_4739"
                     /db_xref="GeneID:5319107"
     CDS             complement(1260715..1262208)
                     /locus_tag="Smed_4739"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21344 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313469.1"
                     /db_xref="GI:150376873"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5319107"
                     /translation="MLLSMHGICKSFNGIPALRSASLEVGEAEVMALVGQNGAGKSTL
                     IKILTGAYRRDEGSIAFAGEDVSFNMPAESQARGIATIYQEINLAPQRSVAENIYLSR
                     EPRRFGLIDRRAMREGAVAVLRTFNLEIDVDQPVAHFSAATRQMVAIARAVTQKARLV
                     IMDEPTSSLDEREVAILFETIRTLKRGGVSVVFIGHRLDELYRICDSVTIMRDGKTVA
                     TGAMAEMPKLALVRHMLGKELAAFEAIAKDADEGAQRPVRLSVENAGAGVRVRNVSLT
                     VREGEISGLAGLLGSGRTETANLIFGADRLERGEIRYKGQARSYRQPAEAIADGIGLV
                     SEDRKVDGIIPDMSIRENMTLALLPKLARSGIVDRARQDEIVASYIAALGIRCTSPDQ
                     PIKELSGGNQQKVLLGRWLCTDPKLLIVDEPTRGIDIGAKAEILRLLRRLADEGLGVL
                     MISSELEELLAAADRVTVLSDGTSVAVLPRRELSEAALFAAMAHQVE"
     misc_feature    complement(1260724..1262205)
                     /locus_tag="Smed_4739"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    complement(1261552..1262202)
                     /locus_tag="Smed_4739"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    complement(1262083..1262106)
                     /locus_tag="Smed_4739"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(1261621..1261623,1261717..1261722,
                     1261957..1261959,1262080..1262088,1262092..1262097))
                     /locus_tag="Smed_4739"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1261957..1261968)
                     /locus_tag="Smed_4739"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(1261765..1261779,1261921..1261932,
                     1261954..1261956))
                     /locus_tag="Smed_4739"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1261717..1261734)
                     /locus_tag="Smed_4739"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1261699..1261710)
                     /locus_tag="Smed_4739"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1261615..1261635)
                     /locus_tag="Smed_4739"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1260793..1261443)
                     /locus_tag="Smed_4739"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            complement(1262311..1263294)
                     /locus_tag="Smed_4740"
                     /db_xref="GeneID:5319108"
     CDS             complement(1262311..1263294)
                     /locus_tag="Smed_4740"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     KEGG: sme:SMb21345 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313470.1"
                     /db_xref="GI:150376874"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="GeneID:5319108"
                     /translation="MNRISRRAFMLAATAAGAIAVAGTVAFAELPKLAQKETYKVGFA
                     QTESNNPWRIAQTNSMKAEAEKLGHQLVYTDAAGSAAKQVADVNSMIAQGVDLIFLAP
                     REEKPLIPAVMAAKKAGIPVILLDRSVDPSLAKAGEDYVTFIGSDFIEEGKRIAEWLI
                     KNANGKSKIIELEGTTGSSPANDRKKGFDETIKTAGGFEIVASQSGDFARDKGRQVAE
                     ALLQAHPDADIVYAHNDEMAIGAIAAIEAAGKVPGKDVLVLSIDGGKEAVQAVIDGKI
                     AAVVECNPRFGPKAFETMLRYAKGEKIDPLVINEDKFYDSTNAAAELANAY"
     sig_peptide     complement(1263208..1263294)
                     /locus_tag="Smed_4740"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.915 at
                     residue 29"
     misc_feature    complement(1262314..1263195)
                     /locus_tag="Smed_4740"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     RbsB; COG1879"
                     /db_xref="CDD:224791"
     misc_feature    complement(1262353..1263177)
                     /locus_tag="Smed_4740"
                     /note="Periplasmic binding domain of ABC-type YtfQ-like
                     transport systems; Region: PBP1_YtfQ_like; cd06309"
                     /db_xref="CDD:107304"
     misc_feature    complement(order(1262449..1262451,1262509..1262511,
                     1262743..1262745,1262917..1262919,1263139..1263141))
                     /locus_tag="Smed_4740"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107304"
     gene            1263518..1264570
                     /locus_tag="Smed_4741"
                     /db_xref="GeneID:5319109"
     CDS             1263518..1264570
                     /locus_tag="Smed_4741"
                     /note="PFAM: regulatory protein LacI; periplasmic binding
                     protein/LacI transcriptional regulator;
                     KEGG: sme:SMb21346 putative transcriptional regulator,
                     LacI family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313471.1"
                     /db_xref="GI:150376875"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5319109"
                     /translation="MTDVARIAGVSQSSVSLVLNEMSGARISAETRARVRDAARKIGY
                     RLPNTRQDLDHAPAIEKDTIAFIVDEISTSPHPVVSLDGIRDYAFEQGLLVSAHATRS
                     NPDLESAVLRSVLRDPAIAGVIYATIFTRKVSVPRELENVPTILLNCYAEPRQHMAIV
                     PGEVAGGFAATAHLTSLGHRRIGFINGEPWMDAAIDRLKGYKQALATADIAYDESLVR
                     NGDWLPLRGYEAALELLAIDNPPTAIFCGNDLMAIGALEAASERGLRVPQDLSVLGYD
                     DQELARYTHPPLSTLVLPNYEMGQKAAEILIDMAIHGKNPRPMTIKVDGPLVKRGTTA
                     AVPERMAGRPFALREG"
     misc_feature    1263518..1264528
                     /locus_tag="Smed_4741"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    1263524..1263661
                     /locus_tag="Smed_4741"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(1263545..1263559,1263563..1263568,1263575..1263577,
                     1263596..1263601,1263608..1263610,1263647..1263649,
                     1263659..1263661)
                     /locus_tag="Smed_4741"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    1263704..1264510
                     /locus_tag="Smed_4741"
                     /note="Ligand-binding domain of DNA-binding regulatory
                     proteins specific to sucrose that are members of the
                     LacI-GalR family of bacterial transcription repressors;
                     Region: PBP1_sucrose_transcription_regulator; cd06288"
                     /db_xref="CDD:107283"
     misc_feature    order(1263704..1263706,1263746..1263754,1263761..1263766,
                     1263770..1263775,1263794..1263808,1263812..1263814,
                     1263845..1263847,1263857..1263859,1263866..1263874,
                     1264190..1264192,1264274..1264276,1264286..1264288,
                     1264295..1264300)
                     /locus_tag="Smed_4741"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:107283"
     misc_feature    order(1263743..1263748,1263755..1263757,1263893..1263895,
                     1263959..1263961,1263998..1264000,1264106..1264108,
                     1264181..1264183,1264343..1264345,1264394..1264396)
                     /locus_tag="Smed_4741"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107283"
     gene            complement(1264619..1264954)
                     /locus_tag="Smed_4742"
                     /db_xref="GeneID:5319110"
     CDS             complement(1264619..1264954)
                     /locus_tag="Smed_4742"
                     /note="PFAM: Cupin 2 conserved barrel domain protein;
                     KEGG: sme:SMb21347 putative pectin degradation protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cupin"
                     /protein_id="YP_001313472.1"
                     /db_xref="GI:150376876"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="GeneID:5319110"
                     /translation="MDTKLFARSTEGEWVELGQGNRRRVILHTDELMLVEFAFEKDGI
                     GAPHSHPHVQASYIAEGRFEVTVGEQTQVLSAGDSFIAPSGVVHGVRALDAGRLIDSF
                     TPHRADFLK"
     misc_feature    complement(1264622..1264954)
                     /locus_tag="Smed_4742"
                     /note="Uncharacterized conserved protein, contains
                     double-stranded beta-helix domain [Function unknown];
                     Region: COG1917"
                     /db_xref="CDD:224829"
     gene            complement(1264964..1265728)
                     /locus_tag="Smed_4743"
                     /db_xref="GeneID:5319111"
     CDS             complement(1264964..1265728)
                     /locus_tag="Smed_4743"
                     /note="TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase;
                     PFAM: short-chain dehydrogenase/reductase SDR; KR domain
                     protein;
                     KEGG: sme:SMb21348 putative 2-deoxy-D-gluconate
                     3-dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="2-deoxy-D-gluconate 3-dehydrogenase"
                     /protein_id="YP_001313473.1"
                     /db_xref="GI:150376877"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR011286"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="GeneID:5319111"
                     /translation="MSLPSSFSLAGRRIVVTGANTGIGQGIAVSVARAGGTVIGVGRS
                     AMDETEKKVADAGGIFIPARTDLADRKAARPLIDGLWDAHGPLHGLVNNAGIIRRADA
                     VDFTETDWDDVIDINLRSLFFLSQGFGRRVIAEKSRGKIVNIASLLSFQGGIRVASYT
                     ASKHGALGITRLLACEWAAKGVNVNAVAPGYITTNNTEALRADEKRSTAILERIPAGR
                     WGTPDDIGDAAVFLLAPASDYMHGAVVPVDGGWLAR"
     misc_feature    complement(1264967..1265710)
                     /locus_tag="Smed_4743"
                     /note="2-deoxy-D-gluconate 3-dehydrogenase; Region: kduD;
                     TIGR01832"
                     /db_xref="CDD:188170"
     misc_feature    complement(1264970..1265710)
                     /locus_tag="Smed_4743"
                     /note="gluconate 5-dehydrogenase (Ga5DH)-like, classical
                     (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347"
                     /db_xref="CDD:187605"
     misc_feature    complement(order(1265138..1265149,1265153..1265164,
                     1265240..1265242,1265252..1265254,1265291..1265299,
                     1265381..1265383,1265441..1265452,1265528..1265536,
                     1265597..1265605,1265660..1265671,1265675..1265677))
                     /locus_tag="Smed_4743"
                     /note="NADP binding site [chemical binding]; other site"
                     /db_xref="CDD:187605"
     misc_feature    complement(order(1265198..1265206,1265210..1265218,
                     1265222..1265227,1265234..1265239,1265246..1265251,
                     1265258..1265263,1265279..1265287,1265342..1265344,
                     1265351..1265353,1265360..1265365,1265372..1265374,
                     1265387..1265389,1265396..1265401,1265408..1265410,
                     1265414..1265428,1265519..1265521))
                     /locus_tag="Smed_4743"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187605"
     misc_feature    complement(order(1265240..1265242,1265252..1265254,
                     1265291..1265293,1265378..1265380))
                     /locus_tag="Smed_4743"
                     /note="active site"
                     /db_xref="CDD:187605"
     gene            complement(1265725..1266570)
                     /locus_tag="Smed_4744"
                     /db_xref="GeneID:5319112"
     CDS             complement(1265725..1266570)
                     /locus_tag="Smed_4744"
                     /EC_number="5.3.1.17"
                     /note="4-deoxy-L-threo-5-hexosulose-uronate
                     ketol-isomerase; catalyzes the interconversion of
                     4-deoxy-L-threo-5-hexosulose uronate to
                     3-deoxy-D-glycero-2,5-hexodiulosonate"
                     /codon_start=1
                     /transl_table=11
                     /product="5-keto-4-deoxyuronate isomerase"
                     /protein_id="YP_001313474.1"
                     /db_xref="GI:150376878"
                     /db_xref="InterPro:IPR007045"
                     /db_xref="GeneID:5319112"
                     /translation="MTGHIDYTIRFAVDPATAARMDTDALRRNFHIGDLFRPGRISLT
                     YSHYDRMIVGGAMPVDAPLPLEAIRPTGTARFLERRELIAVNIGGPGRVEMNGESFRL
                     EPRDMVYAGMGEEVTFSSEDPAAPAKFYLLSAPAHQTLPRRHIRIGDAKRLDLGSAAT
                     SNERSIFQFIHPEGVKTCQLVVGMTQLAPGSVWNTMPCHVHDRRMEAYLYFDLDDSAR
                     ILHLMGEPGETRHIVMAREEAVLSPPWSIHSGCGTANYAFIWAMAGDNVDYTDVEMVA
                     METLR"
     misc_feature    complement(1265728..1266552)
                     /locus_tag="Smed_4744"
                     /note="5-keto-4-deoxyuronate isomerase; Provisional;
                     Region: PRK00924"
                     /db_xref="CDD:179169"
     gene            complement(1266688..1267437)
                     /locus_tag="Smed_4745"
                     /db_xref="GeneID:5319113"
     CDS             complement(1266688..1267437)
                     /locus_tag="Smed_4745"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb21350 putative transcriptional regulator,
                     GntR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001313475.1"
                     /db_xref="GI:150376879"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5319113"
                     /translation="MDLPTERKPKLSERVASSIRQQVLKGEIQAGEKLPTESRISEFF
                     GVSRTVVREAIATLAADGLVEPRQGAGVFVKDHPTIAFGAISLDASNKISHALNVIEV
                     RMGLEIESAGLAALRRNSAQEAQIQEAFFEFDRLLERGESTGKSDFAFHRAIAAATNN
                     PYYVEVLDALGLRAIPCDVSSPWGTESALSREYQKGLQREHLVILQAISGNNPEAARA
                     AMRAHLTASQERYRARLSGQQAAWGAARRDA"
     misc_feature    complement(1266715..1267437)
                     /locus_tag="Smed_4745"
                     /note="Transcriptional regulators [Transcription]; Region:
                     FadR; COG2186"
                     /db_xref="CDD:225097"
     misc_feature    complement(1267213..1267410)
                     /locus_tag="Smed_4745"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(1267222..1267233,1267237..1267242,
                     1267270..1267272,1267279..1267284,1267288..1267302,
                     1267324..1267329,1267333..1267335,1267402..1267404,
                     1267408..1267410))
                     /locus_tag="Smed_4745"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(1266760..1267143)
                     /locus_tag="Smed_4745"
                     /note="This entry represents the C-terminal ligand binding
                     domain of many members of the GntR family; Region: FCD;
                     smart00895"
                     /db_xref="CDD:214892"
     gene            complement(1267446..1268729)
                     /locus_tag="Smed_4746"
                     /db_xref="GeneID:5319114"
     CDS             complement(1267446..1268729)
                     /locus_tag="Smed_4746"
                     /note="TIGRFAM: TRAP dicarboxylate transporter, DctM
                     subunit;
                     PFAM: TRAP C4-dicarboxylate transport system permease DctM
                     subunit;
                     KEGG: sme:SMb21351 putative C4-dicarboxylate large
                     membrane transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctM"
                     /protein_id="YP_001313476.1"
                     /db_xref="GI:150376880"
                     /db_xref="InterPro:IPR004681"
                     /db_xref="InterPro:IPR010656"
                     /db_xref="GeneID:5319114"
                     /translation="MDMMILFGVFTLLMLIGTPIAFCLGVASFATVLYLGLPPLVIFQ
                     RLNSGMSVFSLLAIPFFIYAGDLMVRGGIAQKIVAFAASLVGHIRGGLGQVNIVTATL
                     FGGISGSAVAEAAAVGGLMIPQMKQRGYGADYAVNITSMAALIALMLPPSHNMIIYSI
                     SAGGKISIADLFTAGILPGLLYAAALMVTAYFVARRRGYPTEVFPGFARVGRYLLVST
                     PGLLLIGIIFGGVRSGVFTATESSCIAVLYALAVTVFVYRQMTWRDFVQATFAAVRTT
                     AMVLLIIGMAAAFSWLMAFLRVPAALIDWMNTISENPIIVLLLLNVLMLFLGTFMDMG
                     PTIIICTPIFLPVAMAYGVDPVHFGVIMILNFGIGLNTPPVGAVQFVACAVGKISVWE
                     AMRSIWPFYMAGLIVLGLVTYVPALSLWLPAVFKG"
     sig_peptide     complement(1268637..1268729)
                     /locus_tag="Smed_4746"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.907) with cleavage site probability 0.822 at
                     residue 31"
     misc_feature    complement(1267479..1268711)
                     /locus_tag="Smed_4746"
                     /note="DctM-like transporters; Region: DctM; pfam06808"
                     /db_xref="CDD:219185"
     misc_feature    complement(1267452..1268594)
                     /locus_tag="Smed_4746"
                     /note="TRAP-type C4-dicarboxylate transport system, large
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctQ; COG1593"
                     /db_xref="CDD:224509"
     gene            complement(1268734..1269294)
                     /locus_tag="Smed_4747"
                     /db_xref="GeneID:5319146"
     CDS             complement(1268734..1269294)
                     /locus_tag="Smed_4747"
                     /note="PFAM: Tripartite ATP-independent periplasmic
                     transporter DctQ component;
                     KEGG: sme:SMb21352 putative C4-dicarboxylate small
                     membrane transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite ATP-independent periplasmic
                     transporter DctQ"
                     /protein_id="YP_001313477.1"
                     /db_xref="GI:150376881"
                     /db_xref="InterPro:IPR007387"
                     /db_xref="GeneID:5319146"
                     /translation="MSNGLSKLGRGLSWLGTLSLWTAGVGLVAMTLIVAWQVFCRYVL
                     NDSPSWTEPGAVMLMSWFIFLGAAVGVRENYHLGFDVLLYVVPKSGKIWLRMISDLVA
                     LAFGFGMIWYGAQLVALTWNTVLPSLQISGGWSYVPLVAGGVLICLFALERIVLRLAG
                     EPIDDVLDEMPPAEVAADLETAQIKA"
     misc_feature    complement(1268755..1269243)
                     /locus_tag="Smed_4747"
                     /note="TRAP-type C4-dicarboxylate transport system, small
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctM; COG3090"
                     /db_xref="CDD:225632"
     gene            complement(1269479..1270456)
                     /locus_tag="Smed_4748"
                     /db_xref="GeneID:5319147"
     CDS             complement(1269479..1270456)
                     /locus_tag="Smed_4748"
                     /note="TIGRFAM: TRAP dicarboxylate transporter, DctP
                     subunit;
                     PFAM: TRAP dicarboxylate transporter- DctP subunit;
                     KEGG: sme:SMb21353 putative periplasmic C4-dicarboxylate
                     transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctP"
                     /protein_id="YP_001313478.1"
                     /db_xref="GI:150376882"
                     /db_xref="InterPro:IPR004682"
                     /db_xref="GeneID:5319147"
                     /translation="MKILVKLAAGLVVAAAFMGNAANAQTVLRSSDTHPDGYPTVEAV
                     EYFGELVKERTAGRYSVEVYHSAQLGEEKDTIEQVRSGVIELNRVSMAPFNGTVKESI
                     VPALPYLFRSEEHMHKVMDGAIGDQIKTAFESAGVVVLAFYDAGARSFYNKQKPISSV
                     ADMKGLKFRVIQSDIFVDMVAALGANATPMPYGEVYSGIETGVIDGAENNFPSYDTAK
                     HFEVAKNYSLDEHTILPEVFVMNKAVFDKLTPEDQEIFKQAAKDSVAKQRELWAAKVK
                     ESRGKVEAAGAQITTPEKQGFIDAMKPVYEKHVTDAVLKKMVEDVRAVQ"
     sig_peptide     complement(1270382..1270456)
                     /locus_tag="Smed_4748"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.933 at
                     residue 25"
     misc_feature    complement(1269482..1270381)
                     /locus_tag="Smed_4748"
                     /note="TRAP-type C4-dicarboxylate transport system,
                     periplasmic component [Carbohydrate transport and
                     metabolism]; Region: DctP; COG1638"
                     /db_xref="CDD:224553"
     misc_feature    complement(1269536..1270366)
                     /locus_tag="Smed_4748"
                     /note="Bacterial extracellular solute-binding protein,
                     family 7; Region: SBP_bac_7; pfam03480"
                     /db_xref="CDD:202660"
     gene            complement(1270488..1271897)
                     /locus_tag="Smed_4749"
                     /db_xref="GeneID:5319148"
     CDS             complement(1270488..1271897)
                     /locus_tag="Smed_4749"
                     /EC_number="5.3.1.12"
                     /note="catalyzes the interconversion of D-glucuronate to
                     D-fructuronate or D-galacturonate to D-tagaturonate;
                     functions in glucuronic and galacturonic metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="YP_001313479.1"
                     /db_xref="GI:150376883"
                     /db_xref="InterPro:IPR003766"
                     /db_xref="GeneID:5319148"
                     /translation="MKGLIDPDLLFPGEESTRALARGLYAEVSGLPIVSPHGHTDPRW
                     YALNEAFPDPAQLLIVPDHYVFRMLFSQGISLEMLGVPTLDGSPVATDGRAIWRLFCE
                     NYYLFRGTPTRLWFDYTLSELFGIDELPSAANADRLYDHVAECLARPEYRPRALYERF
                     NIEVISTTDSALDDLDWHARIRDSGWKGRVVPAYRPDAVVDPDFQGFGTNLDKFGEIT
                     GADTGTWTGYLDAHRSRRAYFKTFGATSTDHGHATADTANLPQNEAAALFDRVRLGKA
                     NADERRLFRAQMLTEMAKMSLDDGLVMQIHPGSLRNHSPAILAKFGRDKGFDIPTRTD
                     YVTALKPLLDVVGLERNLTIILFTLDETSYARELAPLAGVYPALKLGPAWWFHDSADG
                     MRRFREMTTETAGFYNTVGFNDDTRAFPSIPARHDIARRVDCAFLAGLVAEHRLRENE
                     AYELARDLAYGLAKKAYRL"
     misc_feature    complement(1270491..1271897)
                     /locus_tag="Smed_4749"
                     /note="glucuronate isomerase; Reviewed; Region: PRK02925"
                     /db_xref="CDD:235087"
     misc_feature    complement(1270491..1271891)
                     /locus_tag="Smed_4749"
                     /note="Glucuronate isomerase [Carbohydrate transport and
                     metabolism]; Region: UxaC; COG1904"
                     /db_xref="CDD:224816"
     gene            1272052..1273071
                     /locus_tag="Smed_4750"
                     /db_xref="GeneID:5319149"
     CDS             1272052..1273071
                     /locus_tag="Smed_4750"
                     /note="PFAM: oxidoreductase domain protein; Oxidoreductase
                     domain;
                     KEGG: sme:SMb21355 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain-containing protein"
                     /protein_id="YP_001313480.1"
                     /db_xref="GI:150376884"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="GeneID:5319149"
                     /translation="MEKTRIGMIGLGMAAAPHAKSLLDLKDRVELAAAFSPTPDRRSA
                     FSESYGFKTCDSVEAIFRDPSIAAVMILTPPNTHLDLVRQAAEAGKHVLLEKPLEITP
                     DRAEALVDVAARAGIKLGIVLQHRFRTVSVELAKLIGEGRLGEIVSASARLHNWRPQS
                     YYDQPGRGMRARDGGGVLLTQAIHTLDLLVSLAGLPEEVKAYATTSRVHRMETEDLAM
                     AAIRFSSGAIGTVSATTCAYPGYPDEIDIIGTRGMARLGGQRLAVSLHDGAELSFEDE
                     AAGGAGADPMAFPHCHHRAVLADFLDAVDGDREPRVNGREALKVHRLIAAVLGAAESG
                     MPQRL"
     misc_feature    1272052..1273068
                     /locus_tag="Smed_4750"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:223745"
     sig_peptide     1272052..1272111
                     /locus_tag="Smed_4750"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.894) with cleavage site probability 0.875 at
                     residue 20"
     misc_feature    1272064..1272414
                     /locus_tag="Smed_4750"
                     /note="Oxidoreductase family, NAD-binding Rossmann fold;
                     Region: GFO_IDH_MocA; pfam01408"
                     /db_xref="CDD:201778"
     misc_feature    1272457..1272741
                     /locus_tag="Smed_4750"
                     /note="Oxidoreductase family, C-terminal alpha/beta
                     domain; Region: GFO_IDH_MocA_C; pfam02894"
                     /db_xref="CDD:217272"
     gene            1273223..1274215
                     /locus_tag="Smed_4751"
                     /db_xref="GeneID:5319150"
     CDS             1273223..1274215
                     /locus_tag="Smed_4751"
                     /note="TIGRFAM: putative ribonuclease BN;
                     PFAM: ribonuclease BN;
                     KEGG: sme:SMb21356 conserved hypothetical membrane
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ribonuclease BN"
                     /protein_id="YP_001313481.1"
                     /db_xref="GI:150376885"
                     /db_xref="InterPro:IPR004664"
                     /db_xref="GeneID:5319150"
                     /translation="MGTNEVELVERLDAAEPGRGRAASAPGEIPVKGMRDVFWRVVSE
                     IAEERVVLIAAGVSFYLLLSLFPALGALVSIYGLVADPSEIGTHMGILQALLPQDSYG
                     LIMDQLKTLTTQKPSTLGMGFFISLSISLWLAANGIAALFDAMNVAYGEREKRGFLFR
                     TVLCIAFTFAALLFAVALIVAIGVVPAVLAHLWVDRWVELVTRVARWPALLLLVTFGT
                     VLIYRFGPSRERAKLRWLNWGAVFSTLFWFAASWLFSYYLEHFANYNATYGALGALAG
                     LMTWVWISVMILIIGALINAELEHQTAVDSTTGEPLPLGERGAHVADTIGKAAN"
     misc_feature    1273277..1274173
                     /locus_tag="Smed_4751"
                     /note="Ribonuclease BN family enzyme [Replication,
                     recombination, and repair]; Region: Rbn; COG1295"
                     /db_xref="CDD:224214"
     gene            1274319..1274603
                     /locus_tag="Smed_4752"
                     /db_xref="GeneID:5319151"
     CDS             1274319..1274603
                     /locus_tag="Smed_4752"
                     /note="KEGG: sme:SMb21357 hypothetical membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313482.1"
                     /db_xref="GI:150376886"
                     /db_xref="GeneID:5319151"
                     /translation="MADRELLGLAASAKVGGHPIHSMLVPFPIALLVATFVQAVWPGG
                     FLLSLLTVLLLLYTGWKGGELVYHHRIGMHPEAEDGTTPPPAVKHRTRHI"
     misc_feature    1274334..>1274429
                     /locus_tag="Smed_4752"
                     /note="Predicted membrane protein (DUF2231); Region:
                     DUF2231; cl01730"
                     /db_xref="CDD:242671"
     misc_feature    <1274433..1274558
                     /locus_tag="Smed_4752"
                     /note="Predicted membrane protein (DUF2231); Region:
                     DUF2231; cl01730"
                     /db_xref="CDD:242671"
     gene            1274686..1275186
                     /locus_tag="Smed_4753"
                     /db_xref="GeneID:5319152"
     CDS             1274686..1275186
                     /locus_tag="Smed_4753"
                     /note="KEGG: sme:SMb21361 hypothetical membrane-anchored
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313483.1"
                     /db_xref="GI:150376887"
                     /db_xref="GeneID:5319152"
                     /translation="MVQPPVRDDGLQIEEHRTFQESFWRAERVSWVIFGLTLIAALLG
                     VTGSGGMLERQIITVADGSVDVPRFSRWEASDVLQATLAGGGSERRLTLSPEFFRTFQ
                     VEDIDPPPIAAEGGADGLVYRFRAASAQPLVLTLHLRAQYPGIVSFRASVNDGPAQAL
                     RTIVWP"
     gene            1275198..1275638
                     /locus_tag="Smed_4754"
                     /db_xref="GeneID:5319153"
     CDS             1275198..1275638
                     /locus_tag="Smed_4754"
                     /note="KEGG: sme:SMb21362 hypothetical membrane-anchored
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313484.1"
                     /db_xref="GI:150376888"
                     /db_xref="GeneID:5319153"
                     /translation="MESVARGITIYFILLVALRLSGRRTVAQMTTFDFVLLLIIAETT
                     QQALLGDDFSIVNAALLILTLFGVDIVLSYLKQWSPKIALVLDGTPTVLIANGNVDDR
                     ALKRARINIDDILVAAREQQGLARLDQIKFAVLEADGGISIIPR"
     misc_feature    1275198..>1275635
                     /locus_tag="Smed_4754"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG2323"
                     /db_xref="CDD:225205"
     gene            1275783..1276769
                     /locus_tag="Smed_4755"
                     /db_xref="GeneID:5319154"
     CDS             1275783..1276769
                     /locus_tag="Smed_4755"
                     /note="TIGRFAM: putative ribonuclease BN;
                     PFAM: ribonuclease BN;
                     KEGG: sme:SMb21363 conserved hypothetical membrane
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ribonuclease BN"
                     /protein_id="YP_001313485.1"
                     /db_xref="GI:150376889"
                     /db_xref="InterPro:IPR004664"
                     /db_xref="GeneID:5319154"
                     /translation="MSSGETSGSGDQARNETNRGRAADSPGEIPARGLRDVFWRVVAQ
                     VSEDRISLVAAGVTFYVLLSVFPALASLVSIYGLVSDPGTIAEQASYLAAILPAQSLQ
                     LMTDQLKALASQNTSSLSLGFIGGLLFALWSARNGVSALFEAMNIAYDETEKRGFIRL
                     ALLSIGFTLAGLILTAVLIGAIAVLPALLSFLDLKLQGIISFARWPVMLLLIAAVITL
                     IYRYGPSREPAKLRWLTWGAALSTVCWLVASLAFSYYIDNFANYNATYGALGALIGFM
                     LWIWISTMIVIVGAELNAELEHQTARDSTTGPPKAIGKRNAYVADTVGDTKD"
     misc_feature    1275837..1276727
                     /locus_tag="Smed_4755"
                     /note="Ribonuclease BN family enzyme [Replication,
                     recombination, and repair]; Region: Rbn; COG1295"
                     /db_xref="CDD:224214"
     gene            complement(1276777..1278321)
                     /locus_tag="Smed_4756"
                     /db_xref="GeneID:5319155"
     CDS             complement(1276777..1278321)
                     /locus_tag="Smed_4756"
                     /note="similar to L-sorbosone dehydrogenase protein; KEGG:
                     sme:SMb21364 putative membrane-anchored oxidoreductase,
                     similar to L-sorbosone dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane-anchored oxidoreductase"
                     /protein_id="YP_001313486.1"
                     /db_xref="GI:150376890"
                     /db_xref="GeneID:5319155"
                     /translation="MNSSAFGAKAIVGTGILLASLAGCDGTDFDVSQQIGPDPVLPEP
                     TSELMPDMKVAEVAGWKDDQTPAVPDSLVITAYAKDLVNPRTVHTLPNGDVLVVQSRE
                     PSGKPIERPKDMIRGWIMSMAHGDGGGAEKESNLVTLLRDTNRDGKVDERHDLLTGLH
                     SPFGVAWRDGTLYVAAADAVLAYSYQLGQAEITAEPQVLTPLPGGPINHHWTKDLALS
                     PDGRYLYASVGSNSNVAERGLEAEKGRAAIWQIDRQTGAARVFASGLRNPNGLAFHPE
                     TGVLWTVVNERDELGPNLVPDFMTSVQEGAFYGWPWSYYGAHVDERVYPPRPDLVEKA
                     VAPDYALSSHVAALGLIFSNGSALPEPFANGAFIGEHGSWNRNTFNGYKVVYVPFENG
                     RPAGKAQDVVTGFLEGDQARGRPVGVAIDGTGALLIADDAGNTVWRVAGADGRVTPNP
                     VGTDGQIGAAVTSEAAPPTGPEGAASGGSAPPAASATPPEPPQTEVAPAVLPRTADEG
                     ASPRQP"
     misc_feature    complement(1276990..1278303)
                     /locus_tag="Smed_4756"
                     /note="Glucose/sorbosone dehydrogenases [Carbohydrate
                     transport and metabolism]; Region: COG2133"
                     /db_xref="CDD:225044"
     gene            complement(1278318..1278767)
                     /locus_tag="Smed_4757"
                     /db_xref="GeneID:5319156"
     CDS             complement(1278318..1278767)
                     /locus_tag="Smed_4757"
                     /note="KEGG: sme:SMb21365 hypothetical membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313487.1"
                     /db_xref="GI:150376891"
                     /db_xref="GeneID:5319156"
                     /translation="MSLTSASTAMTVTTPVHSLLVPFPAVCFTLALLTDIAFWQTGHI
                     MWQNFSAWLLFAGIAFGVISGLVGIVEFLLRSDRRARGSVWLHVVGYVLVLGLAFVNN
                     LVHAGDGWTAVVPYGLILSAATVLLTILVALLGRAVLHRTQTRSERS"
     sig_peptide     complement(1278711..1278767)
                     /locus_tag="Smed_4757"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.645) with cleavage site probability 0.571 at
                     residue 19"
     misc_feature    complement(<1278417..1278761)
                     /locus_tag="Smed_4757"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG4244"
                     /db_xref="CDD:226695"
     gene            1278946..1279536
                     /locus_tag="Smed_4758"
                     /db_xref="GeneID:5318482"
     CDS             1278946..1279536
                     /locus_tag="Smed_4758"
                     /note="KEGG: sme:SMb21366 hypothetical membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313488.1"
                     /db_xref="GI:150376892"
                     /db_xref="GeneID:5318482"
                     /translation="MTGPLAAHMAVHILLMNIVAPLAALGLSRVLQNSRAISGRLLGL
                     ATLVQIAGLWAWHAPPFLNRALESSSVHLLMNGSLFLSAFLFWWAVLHFRGEHSWQPV
                     AALLVTSKLYCLLAVLFVFAPRTLYPDFASSHLGHVVGGPSTDLTDQQLAGLIMLAAC
                     PVTYVLAGVVIAARWLLAMEKEGDDPGSRSGAEAWT"
     misc_feature    <1278946..1279533
                     /locus_tag="Smed_4758"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG3336"
                     /db_xref="CDD:225873"
     gene            1279527..1280648
                     /locus_tag="Smed_4759"
                     /db_xref="GeneID:5318483"
     CDS             1279527..1280648
                     /locus_tag="Smed_4759"
                     /note="KEGG: sme:SMb21367 putative cytochrome c class I
                     protein, probably cytochrome c4"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c class I protein"
                     /protein_id="YP_001313489.1"
                     /db_xref="GI:150376893"
                     /db_xref="InterPro:IPR008169"
                     /db_xref="InterPro:IPR009056"
                     /db_xref="InterPro:IPR011031"
                     /db_xref="GeneID:5318483"
                     /translation="MDLRNLHWTNIAKVAGLGTGLLIVLGAVFVWSGIYNVAASKDHL
                     QITTWILTLIRERSIATHSFKIEVPALDDESKIRLGASHYEGGCVPCHNRPGEEINSI
                     VKGMLPPPPNLLEIGKHRPPEEIFWIVKHGLKYTGMPAWTNVLRDDEVWALTAFLASL
                     PATAGDYGELAGLSRGQGNAREEPANGRALNVCVRCHERDGMSTNGDRVPRLAGMPEA
                     YLLRSLQEYAQGTRASGVMEPVADLLSEEAMRELAAHYQALPPVAGTAEPDPEQLRRG
                     EAIARRGIVGQGVPACLSCHSGRQSQQFPVLAGQNAAYIEEQIRLWRRGGRIGTPYGR
                     IMAAVAGALDEGQIEDVAAYLASLPAGRAPDAPVAEAGR"
     sig_peptide     1279527..1279625
                     /locus_tag="Smed_4759"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.862) with cleavage site probability 0.788 at
                     residue 33"
     misc_feature    1279755..1279997
                     /locus_tag="Smed_4759"
                     /note="Cytochrome C oxidase, cbb3-type, subunit III;
                     Region: Cytochrome_CBB3; pfam13442"
                     /db_xref="CDD:205620"
     misc_feature    1280079..1280372
                     /locus_tag="Smed_4759"
                     /note="Cytochrome c553 [Energy production and conversion];
                     Region: COG2863"
                     /db_xref="CDD:225418"
     misc_feature    <1280394..1280633
                     /locus_tag="Smed_4759"
                     /note="Cytochrome c; Region: Cytochrom_C; cl11414"
                     /db_xref="CDD:245607"
     gene            1280645..1281628
                     /locus_tag="Smed_4760"
                     /db_xref="GeneID:5318484"
     CDS             1280645..1281628
                     /locus_tag="Smed_4760"
                     /note="TIGRFAM: Cytochrome c oxidase subunit II;
                     PFAM: cytochrome c oxidase subunit II; cytochrome c class
                     I;
                     KEGG: sme:SMb21368 putative cytochrome c oxidase chain II
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase subunit II"
                     /protein_id="YP_001313490.1"
                     /db_xref="GI:150376894"
                     /db_xref="InterPro:IPR001505"
                     /db_xref="InterPro:IPR002429"
                     /db_xref="InterPro:IPR003088"
                     /db_xref="InterPro:IPR009056"
                     /db_xref="InterPro:IPR014222"
                     /db_xref="GeneID:5318484"
                     /translation="MSLRRFIVPMSAFAVQGCAGLQSALDPSGAEAERIGTLTWLLII
                     FSTAILVAVCVITAVALFGGERWRARISGERTVIGGGLAFPILALSILLGYGFYLMAP
                     GSTSARVEGGLRIEVVGERWWWRVTYVDESGRRTESANEIRLPVGRPVELELTSADVI
                     HSLWVPRLAGKLDMIPGRTNVLTLEATEPGISRGQCAEYCGGPHAFMSFYVIAMPEDQ
                     FSSWLSGEAEDALAASRDQAAGQALFLSSGCVACHRVRGTDAQGTIGPDLTHVGSRHS
                     LAAATLENDVAAFVRWIREGQHVKPENLMPPFEIFTEDELRQLAAYLDQLR"
     sig_peptide     1280645..1280719
                     /locus_tag="Smed_4760"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.819) with cleavage site probability 0.375 at
                     residue 25"
     misc_feature    1280672..1281361
                     /locus_tag="Smed_4760"
                     /note="Heme/copper-type cytochrome/quinol oxidases,
                     subunit 2 [Energy production and conversion]; Region:
                     CyoA; COG1622"
                     /db_xref="CDD:224537"
     misc_feature    1280981..1281265
                     /locus_tag="Smed_4760"
                     /note="Cytochrome C oxidase subunit II, periplasmic
                     domain; Region: COX2; pfam00116"
                     /db_xref="CDD:201014"
     misc_feature    <1281278..1281625
                     /locus_tag="Smed_4760"
                     /note="Cytochrome c1 [Energy production and conversion];
                     Region: CYT1; COG2857"
                     /db_xref="CDD:225413"
     misc_feature    1281359..1281625
                     /locus_tag="Smed_4760"
                     /note="Cytochrome c; Region: Cytochrom_C; pfam00034"
                     /db_xref="CDD:215669"
     gene            1281635..1282708
                     /locus_tag="Smed_4761"
                     /db_xref="GeneID:5318485"
     CDS             1281635..1282708
                     /locus_tag="Smed_4761"
                     /note="PFAM: sodium/calcium exchanger membrane region;
                     KEGG: sme:SMb21369 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/calcium exchanger membrane protein"
                     /protein_id="YP_001313491.1"
                     /db_xref="GI:150376895"
                     /db_xref="InterPro:IPR004837"
                     /db_xref="GeneID:5318485"
                     /translation="MLDFTGLGLWLNLAIFAGAAVAVWMAGVRITGYANAISEKTGVG
                     QAFIGVVLLGGVTSLPEVTVGVTSSLSADASLAVNSILGGIAMQVAILAFADMLIGRK
                     ALTSVIPDPVVMLQGGFKILLLSIVAASIVVGDVPVLFSGVWMWLLAAVTVFGLWVLS
                     RTRRDRPWIANDEEVTPEKEEDRAREAAESSKKKSLRDIGWATAACGAVIIVAGYLLS
                     RSGDAIADATGLGQSFIGAVLVAIATSLPEVSTVFSATRAGLYTMAMSDIFGTNLIDI
                     FLLFIVDLTGGADAVMNGAGRFEAFAALIAITVTAIFFIGLVERRDRTILKMGYDSFA
                     VLCVYLSGLVVLYFLRDVSGGGG"
     sig_peptide     1281635..1281703
                     /locus_tag="Smed_4761"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.986) with cleavage site probability 0.974 at
                     residue 23"
     misc_feature    1281719..1282684
                     /locus_tag="Smed_4761"
                     /note="Ca2+/Na+ antiporter [Inorganic ion transport and
                     metabolism]; Region: ECM27; COG0530"
                     /db_xref="CDD:223604"
     misc_feature    1281719..1282096
                     /locus_tag="Smed_4761"
                     /note="Sodium/calcium exchanger protein; Region: Na_Ca_ex;
                     pfam01699"
                     /db_xref="CDD:216653"
     misc_feature    1282256..>1282450
                     /locus_tag="Smed_4761"
                     /note="Sodium/calcium exchanger protein; Region: Na_Ca_ex;
                     pfam01699"
                     /db_xref="CDD:216653"
     gene            1282708..1285230
                     /locus_tag="Smed_4762"
                     /db_xref="GeneID:5318486"
     CDS             1282708..1285230
                     /locus_tag="Smed_4762"
                     /EC_number="1.9.3.1"
                     /note="TIGRFAM: Cytochrome c oxidase subunit I type;
                     PFAM: cytochrome c oxidase subunit I;
                     KEGG: sme:SMb21370 putative cytochrome c oxidase chain I
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase subunit I type"
                     /protein_id="YP_001313492.1"
                     /db_xref="GI:150376896"
                     /db_xref="InterPro:IPR000883"
                     /db_xref="InterPro:IPR014241"
                     /db_xref="GeneID:5318486"
                     /translation="MELPNPDPRPEGEVRELERIWATPRGWRMVTAVNNTVIGLLYIG
                     VAFLFFLMAGLLAVVMRTQLAVGDNRLIDQDLYNQMFTVHGTTMMFLFAVPAVEALGV
                     MLLPQMLAARDLPFPRLSAFAIWAYVVGGLVFFSTIFYDLAPKGGWFMYPPLTLMEYS
                     PGDNADFWLLGIGFIEISAIAGAVEIVVGALRTRPPGMSLARMPIFAWTMLIFASMIM
                     FAFPAVILATMMLEIERAFGWPFFTAAVGGDPLLWQHLFWFFGHPEVYIIFLPAAGLV
                     SMMVPTMARTPLVGYHLIVVALIGTGFFSFGLWVHHMFTTGIPALSLAFFSAASMAVA
                     VPSGIQVFSWIATIAAGRQRFRITTASLFILGFLFIFTLGGLTGVMVAMVPFDHQVHD
                     TYFVVAHFHYVLIGGFVFPLFAAIYYWMPLFSRRMLSERVGRWVFWMMFVGFNVTFLP
                     MHLTGLRGMPRRVWTYPGEMGWDTLNLISTAGTYVLAAGILVFLVDLAAKFRIGNRAV
                     ENPWGAGTLEWLPNDVYSTRSIPHITSREPLWDRPSLPQEVRDGHHYLPNAPTGWRET
                     IVTSPIHARPQYVIQMPGPGWPPFLAAVFTAAFFLLLTVKMVAIAVICGVLAIVFVLA
                     WAWGLDPGPSKGMIEIAKGVRLPTYMSGPTSHSWWAMVVLMFVAGSLYLAYVFSYLFL
                     WVVSPEVWAPAGSPAPPPIGWPAGSAALLLAGSGILWLVSRKLQQYAASRLAMSAALL
                     LSLVCLTAAFMLETCGHLTTGLNPGENAYGAMVYLGAVLFAQLVLALLIMGLFTLARH
                     LAGKLDAVRRVTYDNYALLYYYTVAQSLLGLGLIHGFPRLIG"
     misc_feature    1282786..1284450
                     /locus_tag="Smed_4762"
                     /note="Heme/copper-type cytochrome/quinol oxidases,
                     subunit 1 [Energy production and conversion]; Region:
                     CyoB; COG0843"
                     /db_xref="CDD:223913"
     misc_feature    1282792..1284273
                     /locus_tag="Smed_4762"
                     /note="Heme-copper oxidase subunit I.  Heme-copper
                     oxidases are transmembrane protein complexes in the
                     respiratory chains of prokaryotes and mitochondria which
                     catalyze the reduction of O2 and simultaneously pump
                     protons across the membrane.  The superfamily is...;
                     Region: Heme_Cu_Oxidase_I; cl00275"
                     /db_xref="CDD:241744"
     misc_feature    order(1282831..1282833,1283014..1283016,1283044..1283046,
                     1283065..1283067,1283074..1283076,1283239..1283244,
                     1283260..1283262,1283272..1283274)
                     /locus_tag="Smed_4762"
                     /note="D-pathway; other site"
                     /db_xref="CDD:238461"
     misc_feature    order(1282876..1282878,1282888..1282890,1282936..1282938,
                     1282957..1282959,1282969..1282974,1282984..1282986,
                     1283149..1283151,1283887..1283889,1283908..1283910,
                     1283917..1283922,1284088..1284093,1284184..1284186)
                     /locus_tag="Smed_4762"
                     /note="Low-spin heme binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238461"
     misc_feature    order(1283452..1283454,1283467..1283472,1283866..1283868,
                     1283878..1283883,1284088..1284090)
                     /locus_tag="Smed_4762"
                     /note="Putative water exit pathway; other site"
                     /db_xref="CDD:238461"
     misc_feature    order(1283491..1283493,1283638..1283643,1283902..1283904)
                     /locus_tag="Smed_4762"
                     /note="Binuclear center (active site) [active]"
                     /db_xref="CDD:238461"
     misc_feature    order(1283491..1283493,1283503..1283505,1283536..1283538,
                     1283638..1283643,1283716..1283718,1283725..1283727)
                     /locus_tag="Smed_4762"
                     /note="K-pathway; other site"
                     /db_xref="CDD:238461"
     misc_feature    order(1283641..1283643,1283878..1283883,1284088..1284093)
                     /locus_tag="Smed_4762"
                     /note="Putative proton exit pathway; other site"
                     /db_xref="CDD:238461"
     gene            1285236..1285607
                     /locus_tag="Smed_4763"
                     /db_xref="GeneID:5318487"
     CDS             1285236..1285607
                     /locus_tag="Smed_4763"
                     /note="KEGG: sme:SMb21371 hypothetical membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313493.1"
                     /db_xref="GI:150376897"
                     /db_xref="GeneID:5318487"
                     /translation="MNEPIHEPPVAGAILFLLAGPILWGGHLLAVYTFHAVTCAVGGP
                     WATAVVPGSIVAATLAAAGALLLGFSFPGKLAQALRCFDQDDSQPFLIRAGRLLTVLS
                     LAGVLWTGSGALTLAPCVQFR"
     gene            complement(1285611..1286648)
                     /locus_tag="Smed_4764"
                     /db_xref="GeneID:5318488"
     CDS             complement(1285611..1286648)
                     /locus_tag="Smed_4764"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     SMART: regulatory protein LacI;
                     KEGG: sme:SMb21372 putative transcriptional regulator,
                     LacI family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313494.1"
                     /db_xref="GI:150376898"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5318488"
                     /translation="MTRQIKTMEDFSEFVGLSRPTVSKYFNDPSSVRKKTRDAIEAAI
                     KQSGFRPNIFAVNLNRRRTNILGIIVPNSTDPFYMALTRRIEHIADQSGFLAFVLSSD
                     GRPELEERAIETFKSMNVAGAIIAPLGVQSHHQTLSALGQSIPLIYVDSPLDDSSPFV
                     GTDNRQSFRLMVDYLCRSGDPPCYFGMPPVNNNALVRQEAYVEAMRQLKMKPAVVETA
                     ANASWDFEKFGFDETLRILSQGGFPTRTVLCANDRVAFGVIAAAFQSGLKVGRDAESD
                     LRVAGHDDHPLSRYTCPPLTTVAQNYNEIGRLAIELLLFKLGETSHNGEAFRDDERIL
                     LSAEIMLRGSA"
     misc_feature    complement(1285617..1286630)
                     /locus_tag="Smed_4764"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    complement(1286469..1286603)
                     /locus_tag="Smed_4764"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    complement(order(1286472..1286477,1286481..1286486,
                     1286493..1286495,1286502..1286504,1286541..1286543,
                     1286550..1286555,1286568..1286570,1286577..1286582,
                     1286586..1286600))
                     /locus_tag="Smed_4764"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    complement(1286475..1286504)
                     /locus_tag="Smed_4764"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    complement(1285629..1286456)
                     /locus_tag="Smed_4764"
                     /note="Ligand binding domain of the LacI tanscriptional
                     regulator family belonging to the type I
                     periplasmic-binding fold protein superfamily; Region:
                     PBP1_LacI_sugar_binding_like; cd06267"
                     /db_xref="CDD:107262"
     misc_feature    complement(order(1285857..1285862,1285869..1285871,
                     1285881..1285883,1285971..1285973,1286292..1286300,
                     1286307..1286309,1286316..1286318,1286349..1286351,
                     1286355..1286369,1286388..1286393,1286397..1286402,
                     1286409..1286417,1286454..1286456))
                     /locus_tag="Smed_4764"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:107262"
     misc_feature    complement(order(1285749..1285751,1285800..1285802,
                     1285980..1285982,1286058..1286060,1286163..1286165,
                     1286199..1286201,1286271..1286273,1286406..1286408,
                     1286415..1286420))
                     /locus_tag="Smed_4764"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107262"
     gene            complement(1286822..1288102)
                     /locus_tag="Smed_4765"
                     /db_xref="GeneID:5318489"
     CDS             complement(1286822..1288102)
                     /locus_tag="Smed_4765"
                     /EC_number="2.7.1.144"
                     /note="PFAM: D-tagatose-bisphosphate aldolase class II
                     accessory protein AgaZ;
                     KEGG: sme:SMb21373 putative sugar kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="YP_001313495.1"
                     /db_xref="GI:150376899"
                     /db_xref="InterPro:IPR012062"
                     /db_xref="GeneID:5318489"
                     /translation="MQENYLIDIARWSERPGARGIPSICSAHPLVIEAAMLSARREGT
                     PVLIEATCNQVNQDGGYTGMTPADFTRFVGAIADRLDFPRDRILLGGDHLGPNPWKHL
                     PAEKAMAKAETMIEAYAKAGFTKLHLDTSMGCAGEPIALPDATTAARAARLAAVAENA
                     IRDRGGILPVYIIGTEVPIPGGALEELDVLEVTAPEAAIETVRVHREAFKEAGAAGAF
                     SRVVGAVVQPGVEFGNGNVIAYDRSKAAKLSASLRRLEGMVFEAHSTDYQTREALREL
                     VADGFAILKVGPGLTFALREALYGLDQIAAFLFPGKRERSLAEVTEAVMREEPVYWGK
                     YYHGSADEQRIQRHFSYSDRIRYYWPHQKMAEAVDELMALLDGVTIPETLISQFLAGS
                     YARVRDGEVAPQAKPLALAAIDAVLQDYFAACRL"
     misc_feature    complement(1286825..1288093)
                     /locus_tag="Smed_4765"
                     /note="Tagatose 6 phosphate kinase; Region:
                     Tagatose_6_P_K; pfam08013"
                     /db_xref="CDD:203838"
     gene            complement(1288105..1289046)
                     /locus_tag="Smed_4766"
                     /db_xref="GeneID:5318490"
     CDS             complement(1288105..1289046)
                     /locus_tag="Smed_4766"
                     /note="PFAM: PfkB domain protein;
                     KEGG: sme:SMb21374 putative sugar kinase, PfkB family
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase-like domain-containing protein"
                     /protein_id="YP_001313496.1"
                     /db_xref="GI:150376900"
                     /db_xref="InterPro:IPR011611"
                     /db_xref="GeneID:5318490"
                     /translation="MHKILTIGEILVEIVATERGDGFRQATPLIGPFPSGAPAIFIDQ
                     AGKLGQPCAIISRVGGDDFGTVNLERLKGDGVDISGIEVDPLATTGSAFVRYRPDGSR
                     AFVFNIRDSACGKITLDSRATRLVSECGHIHVMGSSLYAPSVVDSILEAIRIVKAGAG
                     TVSFDPNLRPEILESPGMREALLTVLAKTDVFLPSGEELFLFTEARTESEAVAELLAT
                     GVKAVVVKRGAEGASYFDASTSLTLPSFSVEEIDPTGAGDCFGATFVTFWLNGASPRE
                     ALEFATASGARAVMHFGPMEGASTRTELEIFLTEQKA"
     misc_feature    complement(1288111..1289040)
                     /locus_tag="Smed_4766"
                     /note="Sugar kinases, ribokinase family [Carbohydrate
                     transport and metabolism]; Region: RbsK; COG0524"
                     /db_xref="CDD:223598"
     misc_feature    complement(1288162..1289040)
                     /locus_tag="Smed_4766"
                     /note="2-keto-3-deoxygluconate kinase (KdgK)
                     phosphorylates 2-keto-3-deoxygluconate (KDG) to form
                     2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the
                     common intermediate product, that allows organisms to
                     channel D-glucuronate and/or D-galacturinate into the...;
                     Region: KdgK; cd01166"
                     /db_xref="CDD:238571"
     misc_feature    complement(order(1288165..1288167,1288273..1288275,
                     1288282..1288284,1288540..1288542,1288636..1288638,
                     1288723..1288725,1288729..1288731,1288771..1288773,
                     1288927..1288929,1288936..1288941))
                     /locus_tag="Smed_4766"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238571"
     misc_feature    complement(order(1288189..1288191,1288201..1288203,
                     1288267..1288269,1288276..1288284,1288309..1288311,
                     1288354..1288356,1288369..1288371))
                     /locus_tag="Smed_4766"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238571"
     gene            complement(1289070..1290032)
                     /locus_tag="Smed_4767"
                     /db_xref="GeneID:5318491"
     CDS             complement(1289070..1290032)
                     /locus_tag="Smed_4767"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb21375 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001313497.1"
                     /db_xref="GI:150376901"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318491"
                     /translation="MTQNTETKAALVRALKQYGGIFLSLVMLCIVFSFFNPRFMTLIN
                     FMNILQQVAVIAIAAFGMTWVILLGEIDLSVGSIIAVAGMVGAQCFAFGMGFVPAIAL
                     TLLAGALMGMLNGVLTAKLLLPSFIVTVATMGIYRGMVSLPTNGAPAMIENETWTAIG
                     TESFLGLPIIIWVVAVLFVVNQIALSKTSFGRRAYLTGGNREAAVYSGIKVDRLKILI
                     FMISGVMAAISGILLSSRLFSAQTNAGMSYELDAIAAAVLGGTSLAGGVGTMVGTLIG
                     ALIIGVMNNGMNMLSVPYFYQLIVKGLVILIAVWLDVRAKQAKR"
     misc_feature    complement(1289097..1289855)
                     /locus_tag="Smed_4767"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(1289106..1289852)
                     /locus_tag="Smed_4767"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(1289373..1289429)
                     /locus_tag="Smed_4767"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(1290029..1291540)
                     /locus_tag="Smed_4768"
                     /db_xref="GeneID:5318492"
     CDS             complement(1290029..1291540)
                     /locus_tag="Smed_4768"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21376 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313498.1"
                     /db_xref="GI:150376902"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318492"
                     /translation="MHGSAADTILKITDVTKSFGQVAALKGMRLEVRRGRVHTLLGEN
                     GAGKSTLMKILAGVHTATSGEITLDGQAYRPASPQDAASLGLAIVFQELSLCNNLTVA
                     ENILATREPRRFGFINDKALVAQARRIVADLGLPIDVTEKVGNLSIAQRQLVEIAKGL
                     SHDAEVVILDEPTSSLSDSEAEILFAIIARLKERGVAIIYISHRMEEIMRLSDDITVI
                     RDGEYVSTHAREEVTIEALIALMVGRRMDEIYPPAVHAVARDKAPVLSVERLTREGEF
                     QDVSFEVRAGEILGFFGLVGSGRSEVMNAIFGMKNASGAVRLNGEVVRFRSPDEAIAR
                     RVGFVTENRKEEGLVLGHSVEWNISMAALGDFTGGFGFIRNGAERAAASAQVGNLSIK
                     TNSLDTPSGALSGGNQQKIVIAKWLLTRPRVLILDEPTRGVDVGAKFEIYKIIRQLAA
                     EGTAILLISSDLPEVLGMSDRVVVMHEGAPGATLEGPDLTPETIMAHATGFQS"
     misc_feature    complement(1290041..1291531)
                     /locus_tag="Smed_4768"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    complement(1290863..1291513)
                     /locus_tag="Smed_4768"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    complement(1291394..1291417)
                     /locus_tag="Smed_4768"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(1290932..1290934,1291028..1291033,
                     1291268..1291270,1291391..1291399,1291403..1291408))
                     /locus_tag="Smed_4768"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1291268..1291279)
                     /locus_tag="Smed_4768"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(1291076..1291096,1291130..1291138))
                     /locus_tag="Smed_4768"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1291028..1291045)
                     /locus_tag="Smed_4768"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1291010..1291021)
                     /locus_tag="Smed_4768"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1290926..1290946)
                     /locus_tag="Smed_4768"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1290107..1290757)
                     /locus_tag="Smed_4768"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            complement(1291642..1292532)
                     /locus_tag="Smed_4769"
                     /db_xref="GeneID:5319250"
     CDS             complement(1291642..1292532)
                     /locus_tag="Smed_4769"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     KEGG: sme:SMb21377 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313499.1"
                     /db_xref="GI:150376903"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5319250"
                     /translation="MNMTRFLQTIVAGTALTLLASGAFADGIGASLLTQQHPFYIELA
                     EAMKAEAKEKNVALEVAIANQDLNKQLADVEDFIVKGVDVIVISPVDSQGVRAAIAKA
                     EKAGIKVITVDVPANGATVTSHIGTDNFTGGVKAGELMAKVLGSKGKVAIVDYPTVQS
                     VVNRVNGFKEAIAKHPEMEIVAVQTGITRAEALAAAQNMLQANPDISGIFGFGDDAAL
                     AAAVAVKAAGLESQVKVIGFDGMKEARDAVDSNPVMVGVIQQFPDQMGKQAIDTAVKV
                     VAGETVPAEQPIVPGVYTAK"
     sig_peptide     complement(1292455..1292532)
                     /locus_tag="Smed_4769"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 26"
     misc_feature    complement(1291651..1292454)
                     /locus_tag="Smed_4769"
                     /note="Type 1 periplasmic binding fold superfamily;
                     Region: Periplasmic_Binding_Protein_Type_1; cl10011"
                     /db_xref="CDD:245225"
     misc_feature    complement(1291657..1292451)
                     /locus_tag="Smed_4769"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     RbsB; COG1879"
                     /db_xref="CDD:224791"
     gene            complement(1292725..1293111)
                     /locus_tag="Smed_4770"
                     /db_xref="GeneID:5319251"
     CDS             complement(1292725..1293111)
                     /locus_tag="Smed_4770"
                     /note="PFAM: glutathione-dependent formaldehyde-activating
                     GFA;
                     KEGG: sme:SMb21378 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde-activating
                     protein"
                     /protein_id="YP_001313500.1"
                     /db_xref="GI:150376904"
                     /db_xref="InterPro:IPR006913"
                     /db_xref="GeneID:5319251"
                     /translation="MVTRTGGCLCGALRYEVSGEPLRVGLCHCSDCRKESGSSFVTFA
                     VWPSPAFKSTGEVKIFAGRGFCPVCGSRLFNPGKDETEIRVGSLDNVPAGLEPQYEIW
                     VVRRENWLPPLLVPQYSQDRNTEESD"
     misc_feature    complement(1292746..1293111)
                     /locus_tag="Smed_4770"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3791"
                     /db_xref="CDD:226314"
     gene            1293322..1293696
                     /locus_tag="Smed_4771"
                     /db_xref="GeneID:5319252"
     CDS             1293322..1293696
                     /locus_tag="Smed_4771"
                     /note="PFAM: protein of unknown function DUF427;
                     KEGG: sme:SMb21379 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313501.1"
                     /db_xref="GI:150376905"
                     /db_xref="InterPro:IPR007361"
                     /db_xref="GeneID:5319252"
                     /translation="MSEKPIRIPGPDHPITVERNPARVVVKLGDRIVADTRHALTLRE
                     ASYPPVQYIPRRDVDMSLLARTDHGTYCPYKGDASYFSLTPGGERSKNAVWTYENPHE
                     AVREIKDHLAFYPDRVDSIEEV"
     misc_feature    1293322..1293690
                     /locus_tag="Smed_4771"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG2343"
                     /db_xref="CDD:225220"
     gene            complement(1293858..1294061)
                     /locus_tag="Smed_4772"
                     /db_xref="GeneID:5319253"
     CDS             complement(1293858..1294061)
                     /locus_tag="Smed_4772"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313502.1"
                     /db_xref="GI:150376906"
                     /db_xref="GeneID:5319253"
                     /translation="MTLWASELDRSLKILTKKVAIGAAYTTGGSHAGIKLDRAARLDR
                     HDVNVTACLCGVVYEDDTKEDFK"
     gene            complement(1294987..1295262)
                     /locus_tag="Smed_4773"
                     /db_xref="GeneID:5319254"
     CDS             complement(1294987..1295262)
                     /locus_tag="Smed_4773"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313503.1"
                     /db_xref="GI:150376907"
                     /db_xref="GeneID:5319254"
                     /translation="MVHFALNLGAAMLNSEEIDIPCPECGHEASKTVDWVKANDELSC
                     RRCGSVINLENERPFLIIAHVTRRIAKLRRSLAKFRNNPRGGAKKRR"
     misc_feature    complement(1295089..>1295250)
                     /locus_tag="Smed_4773"
                     /note="peptide chain release factor 1; Provisional;
                     Region: PRK04011"
                     /db_xref="CDD:235198"
     gene            complement(1295369..1295560)
                     /locus_tag="Smed_4774"
                     /db_xref="GeneID:5319255"
     CDS             complement(1295369..1295560)
                     /locus_tag="Smed_4774"
                     /note="KEGG: sme:SMb21395 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313504.1"
                     /db_xref="GI:150376908"
                     /db_xref="GeneID:5319255"
                     /translation="MDDLKAKSAGGIELACDLSEVAAQCAASNLLDFAAQLAGLAEDL
                     KDLAAKPIEPVTVAVEPDS"
     gene            1295742..1296521
                     /locus_tag="Smed_4775"
                     /db_xref="GeneID:5319256"
     CDS             1295742..1296521
                     /locus_tag="Smed_4775"
                     /note="KEGG: sme:SMb20922 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase-like protein"
                     /protein_id="YP_001313505.1"
                     /db_xref="GI:150376909"
                     /db_xref="InterPro:IPR000726"
                     /db_xref="GeneID:5319256"
                     /translation="MSAITVQHVRAAAKGKVNESNLASVLARWVRGSIRDGPAAPSRP
                     GFAQLMHESGDFRYDREICGPTPAQQCYDTRTDLGNTPAKDGDGHLYRGRAGMQLTGK
                     DNYRQFRNWCCAAGLDCLDFVKDPDAVNTGPWEGLMPMFYWATRNLNRWADEGDAETI
                     TKKINGGKNSLADRLDRLARMSLVLFEYRADNVLQFQADERLQVDGDVGPKTRAAMHK
                     ALVALTPGEAARPEVKAAPGTEEKPVTITPRGLDACGSRKR"
     misc_feature    1295748..1296296
                     /locus_tag="Smed_4775"
                     /note="Predicted chitinase [General function prediction
                     only]; Region: COG3179"
                     /db_xref="CDD:225720"
     misc_feature    1295895..1295897
                     /locus_tag="Smed_4775"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238249"
     misc_feature    <1296318..1296389
                     /locus_tag="Smed_4775"
                     /note="Putative peptidoglycan binding domain; Region:
                     PG_binding_1; pfam01471"
                     /db_xref="CDD:216518"
     gene            1296518..1296940
                     /locus_tag="Smed_4776"
                     /db_xref="GeneID:5319257"
     CDS             1296518..1296940
                     /locus_tag="Smed_4776"
                     /note="KEGG: sme:SMb20922 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313506.1"
                     /db_xref="GI:150376910"
                     /db_xref="GeneID:5319257"
                     /translation="MITPSASAAAFRCLRRSAEIPWPNLLLILVAFVGITGFLAQERR
                     SEGRGKTGRGDGVMFSTPRLIAAAAALAIVVAVVVWIYRQGGDEVRTSIERQNNKAGR
                     TADDVRSRFDLCPAGMWNFGAGKCRLSPASGGRLAESP"
     gene            1297160..1297564
                     /locus_tag="Smed_4777"
                     /db_xref="GeneID:5319258"
     CDS             1297160..1297564
                     /locus_tag="Smed_4777"
                     /note="PFAM: BA14K family protein;
                     KEGG: sme:SMa0639 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="BA14K family protein"
                     /protein_id="YP_001313507.1"
                     /db_xref="GI:150376911"
                     /db_xref="InterPro:IPR012413"
                     /db_xref="GeneID:5319258"
                     /translation="MKASTLAFAVLAAAISMSPARAQTCIGICNGGTGGSTNHNLFIE
                     REYRDFLQQRYPNYGSRYRGMSPDISIGPGATVGGPRPGVRQKFRLRQPRAIDAKRHL
                     RWCQERYLSYRLADDTFQPFEGARRPCNSPYN"
     sig_peptide     1297160..1297228
                     /locus_tag="Smed_4777"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.996 at
                     residue 23"
     misc_feature    1297457..1297549
                     /locus_tag="Smed_4777"
                     /note="BA14K-like protein; Region: BA14K; pfam07886"
                     /db_xref="CDD:203793"
     gene            1297650..1297955
                     /locus_tag="Smed_4778"
                     /db_xref="GeneID:5319259"
     CDS             1297650..1297955
                     /locus_tag="Smed_4778"
                     /note="KEGG: sme:SMb20921 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313508.1"
                     /db_xref="GI:150376912"
                     /db_xref="GeneID:5319259"
                     /translation="MFENLIVLVVTTSRRSPASQLPAHARPSRGTVSALALTFVLQGC
                     GTSAPVSADGPRRVVGTDLIGERSATSEDQRKIDRTVVGICAAAVWTTAECARHGEA"
     gene            1298019..1298180
                     /locus_tag="Smed_4779"
                     /db_xref="GeneID:5319260"
     CDS             1298019..1298180
                     /locus_tag="Smed_4779"
                     /note="KEGG: sme:SMb20920 hypothetical secreted protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313509.1"
                     /db_xref="GI:150376913"
                     /db_xref="GeneID:5319260"
                     /translation="MVATPKWRVEYNLNTLVILFGFAGGLIAWGATWERVNANQDSQA
                     NSIDRIDKR"
     sig_peptide     1298019..1298111
                     /locus_tag="Smed_4779"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.732) with cleavage site probability 0.680 at
                     residue 31"
     gene            1298335..1298721
                     /locus_tag="Smed_4780"
                     /db_xref="GeneID:5318402"
     CDS             1298335..1298721
                     /locus_tag="Smed_4780"
                     /note="PFAM: transposase IS3/IS911 family protein;
                     KEGG: atc:AGR_pAT_530 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS3/IS911 family protein"
                     /protein_id="YP_001313510.1"
                     /db_xref="GI:150376914"
                     /db_xref="InterPro:IPR002514"
                     /db_xref="GeneID:5318402"
                     /translation="MSAPIASPRTIHMIEAVPERLEGSPRQLRRFWSDEFKAFAVEEA
                     SRPGANISAVARQIGILPSQLFRWRRELSGDGEQSSALAKEQQPRSAAIRERVVEVVI
                     GDAVVRAGADVEEAHLQRVIRAVRSA"
     misc_feature    1298419..1298631
                     /locus_tag="Smed_4780"
                     /note="Transposase; Region: HTH_Tnp_1; pfam01527"
                     /db_xref="CDD:201841"
     misc_feature    1298419..>1298550
                     /locus_tag="Smed_4780"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG2963"
                     /db_xref="CDD:225511"
     gene            1298718..1299062
                     /locus_tag="Smed_4781"
                     /db_xref="GeneID:5318403"
     CDS             1298718..1299062
                     /locus_tag="Smed_4781"
                     /note="PFAM: IS66 Orf2 family protein;
                     KEGG: rle:pRL70145 putative transposase related protein"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 Orf2 family protein"
                     /protein_id="YP_001313511.1"
                     /db_xref="GI:150376915"
                     /db_xref="InterPro:IPR008878"
                     /db_xref="GeneID:5318403"
                     /translation="MIPSGVKVFLASHPVDFRKGPDSLLSLVRDAGNDPFNGALYVFR
                     AKRADRVKIVWWDGSGVCLYAKRLEKAQFCWPRIGHNRVQLNHAQLLALIDGMDWKRV
                     RSVPVKPPEIVG"
     misc_feature    1298718..1299050
                     /locus_tag="Smed_4781"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG3436"
                     /db_xref="CDD:225970"
     misc_feature    1298727..1299038
                     /locus_tag="Smed_4781"
                     /note="IS66 Orf2 like protein; Region: TnpB_IS66;
                     pfam05717"
                     /db_xref="CDD:191353"
     gene            1299137..1300729
                     /locus_tag="Smed_4782"
                     /db_xref="GeneID:5318404"
     CDS             1299137..1300729
                     /locus_tag="Smed_4782"
                     /note="PFAM: transposase IS66;
                     KEGG: ret:RHE_CH03056 probable insertion sequence
                     transposase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS66"
                     /protein_id="YP_001313512.1"
                     /db_xref="GI:150376916"
                     /db_xref="InterPro:IPR004291"
                     /db_xref="GeneID:5318404"
                     /translation="MTPPDLKLPDDVEALKAMVLAMAEKAARADALQNEVADLKARNA
                     DADERIERLTQILKAFDRARFGRRSEKLGSPTTDDEQQAFVFEEIETGIAAIRAQVNK
                     GRERPEGKRPPRPRKGFAPHLERIEVVIEPEELPEHAGKQKVLIGEDVSERLDVMPAK
                     FRVIVTRRPKYAFKNEDGVIQAAAPAHIIEAGIPTEALLAQIAVSKYADGLPLYRQEA
                     IYARDKVELDRKLMAQWMGKLGFELEILADYLFDEIKKGERIFADETTLPTLAPGSGS
                     TKTAYLWAYARDDRPFGGSGPPMVVYRFEDSRAGECVARHLKGYRGILQVDGYAAYNK
                     LVRSDRGNDGVTLAGCWSHSRRKFYELHVAESSKVATETVERMAKLWQIEETIRGKSP
                     EARVAARQHTSVAVVAELFALWQKTLPRISGKSKLAEALRYAISRRAIFERFLTDGRI
                     ELDSNIVERAIRPQAITRKNSLFAGSDGGGRTWATIATLLQTAKMNNLDPLAWLTQTL
                     ERIANGWPSSEIDALMPWNYAA"
     misc_feature    1299287..>1299433
                     /locus_tag="Smed_4782"
                     /note="Transposase C of IS166 homeodomain; Region:
                     LZ_Tnp_IS66; pfam13007"
                     /db_xref="CDD:221891"
     misc_feature    1299554..1299691
                     /locus_tag="Smed_4782"
                     /note="putative Helix-turn-helix domain of transposase
                     IS66; Region: HTH_Tnp_IS66; pfam13005"
                     /db_xref="CDD:221890"
     misc_feature    <1299566..1299937
                     /locus_tag="Smed_4782"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG3436"
                     /db_xref="CDD:225970"
     misc_feature    1299710..1300582
                     /locus_tag="Smed_4782"
                     /note="Transposase IS66 family; Region: DDE_Tnp_IS66;
                     pfam03050"
                     /db_xref="CDD:217337"
     misc_feature    1300598..1300717
                     /locus_tag="Smed_4782"
                     /note="IS66 C-terminal element; Region: DDE_Tnp_IS66_C;
                     pfam13817"
                     /db_xref="CDD:205990"
     gene            1300781..1300978
                     /locus_tag="Smed_4783"
                     /db_xref="GeneID:5318405"
     CDS             1300781..1300978
                     /locus_tag="Smed_4783"
                     /note="KEGG: sme:SMb20920 hypothetical secreted protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313513.1"
                     /db_xref="GI:150376917"
                     /db_xref="GeneID:5318405"
                     /translation="MKAVENTLNSLSIDTRVMREILQRIEASQRDGAQLRRDDRVARQ
                     ALLNSTSCATYFSLLSSSHGH"
     gene            complement(1301381..1301820)
                     /locus_tag="Smed_4784"
                     /pseudo
                     /db_xref="GeneID:5318406"
     gene            complement(1302029..1303278)
                     /locus_tag="Smed_4785"
                     /pseudo
                     /db_xref="GeneID:5318407"
     gene            1303585..1305144
                     /locus_tag="Smed_4786"
                     /db_xref="GeneID:5318408"
     CDS             1303585..1305144
                     /locus_tag="Smed_4786"
                     /note="PFAM: lipopolysaccharide biosynthesis protein;
                     KEGG: jan:Jann_4239 lipopolysaccharide biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="YP_001313514.1"
                     /db_xref="GI:150376918"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="GeneID:5318408"
                     /translation="MMNGADARFYFSILLRRLPYLVAIVGSVIALTVIVASILPPRYR
                     ASAKILVEAPQIPVELARSTVPIQAAQQLQIIRQQITTRDDLLALADMLDIYGKEEDE
                     LSKDDIVDNMRSRITFEELALSAPYGDTGASVASVSFTAADPDLAARVANELVDFILL
                     KQQQQRTSRAADTVKFFDQAVARLGTDLSRAELEILRYKNEHADTLPESLDFRRSQQT
                     GQQQRWITLEREESDLRAKRSTLVESYVLGGQAPDGKAATPEQLALQELTRALAEQRA
                     IFSENSPNIMALRGRIASLQATLRTTQTSEASSAQDRVARSPLDQQLAYIDERLRAIV
                     GEKAAITDRIDELSKSISATPESETVLYSFERDRANLQSQYNTAIARRAEAIIGQQIE
                     RRSDGSSFSVLERATAPEMAESPNRRRIVLLGALAGTALSVAFIGLLEFFNAAIRRPN
                     ELARLLDRQPLATIPYISTVAEVRSRIRRTVAAVLAAAAAPAALIVVHQFYMPLPIAF
                     QNLYRWLTTLA"
     misc_feature    1303612..1305024
                     /locus_tag="Smed_4786"
                     /note="polysaccharide chain length determinant protein,
                     PEP-CTERM locus subfamily; Region: pepcterm_ChnLen;
                     TIGR03007"
                     /db_xref="CDD:234084"
     misc_feature    <1304617..1304979
                     /locus_tag="Smed_4786"
                     /note="Chain length determinant protein; Region: Wzz;
                     cl15801"
                     /db_xref="CDD:247074"
     gene            1305197..1305964
                     /locus_tag="Smed_4787"
                     /db_xref="GeneID:5318409"
     CDS             1305197..1305964
                     /locus_tag="Smed_4787"
                     /note="KEGG: jan:Jann_4240 ATPases involved in chromosome
                     partitioning-like"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning ATPase"
                     /protein_id="YP_001313515.1"
                     /db_xref="GI:150376919"
                     /db_xref="GeneID:5318409"
                     /translation="MEHAETTLHEFPEAERLSRIGAEPVWKMLSPCRADPRSVAGSWF
                     VTTGRSNPKHAAFDMLRTKLLLALQQKNWKTVAITSPTPGCGKTFVALNLAFSLANQK
                     DCRTVLVDLDLKRPQIAKTLGIEAPSTIEKYLKGESEIGDVFQRYSDNLAIGASKQAV
                     PFSAELLQTRGAVKQLQEMQQKMNPDVVLFDMPPMLSNDDVVGFLPNVDCVILIAASE
                     QSTLAEVDICEQELSERTNVLGVVLNKCRFAPEKYGY"
     misc_feature    1305365..1305928
                     /locus_tag="Smed_4787"
                     /note="exopolysaccharide/PEP-CTERM locus tyrosine
                     autokinase; Region: pepcterm_TyrKin; TIGR03018"
                     /db_xref="CDD:132063"
     misc_feature    1305422..>1305535
                     /locus_tag="Smed_4787"
                     /note="This protein family consists of proteins similar to
                     the cpaE protein of the Caulobacter pilus assembly and the
                     orf4 protein of Actinobacillus pilus formation gene
                     cluster. The function of these proteins are unkown. The
                     Caulobacter pilus assembly contains...; Region: CpaE_like;
                     cd03111"
                     /db_xref="CDD:239385"
     gene            1305981..1306928
                     /locus_tag="Smed_4788"
                     /db_xref="GeneID:5318410"
     CDS             1305981..1306928
                     /locus_tag="Smed_4788"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: ace:Acel_1912 glycosyl transferase, family 2"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313516.1"
                     /db_xref="GI:150376920"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318410"
                     /translation="MVAILKAVPHDEAKKADRTAPRPLSAVIVTYNSSAVLSELLDSL
                     PAGLAGVDDYEVIVVDNASEDRSVDIALDHPIGVRVIKMARNAGYSAGINAAAEAIEP
                     NRNLLVLNPDIRLYPGAARILNDLLSDTSVGIVVPQILDEDGSISRSIRREPSLKTVW
                     ADALVGSDIAGRFGLSETVFDRALYRDGGQIEWAVGAILAIAARTRAIIGGWDEAFFL
                     YSEEVDYQDRVRRAGLSIIYQSEARVVHIGGDFQSNPALCYLMSANRVRYYNGRHGAL
                     PATMFRLGVIAGEILRLPLGQRHRAALRGAISAAARQPR"
     misc_feature    1306050..1306859
                     /locus_tag="Smed_4788"
                     /note="Predicted glycosyltransferases [General function
                     prediction only]; Region: COG1216"
                     /db_xref="CDD:224137"
     misc_feature    1306059..1306724
                     /locus_tag="Smed_4788"
                     /note="Subfamily of Glycosyltransferase Family GT2 of
                     unknown function; Region: GT_2_like_c; cd04186"
                     /db_xref="CDD:133029"
     misc_feature    order(1306161..1306163,1306311..1306316)
                     /locus_tag="Smed_4788"
                     /note="Probable Catalytic site; other site"
                     /db_xref="CDD:133029"
     misc_feature    order(1306314..1306316,1306644..1306646,1306650..1306652)
                     /locus_tag="Smed_4788"
                     /note="metal-binding site"
                     /db_xref="CDD:133029"
     gene            complement(1307054..1307260)
                     /locus_tag="Smed_4789"
                     /db_xref="GeneID:5318411"
     CDS             complement(1307054..1307260)
                     /locus_tag="Smed_4789"
                     /note="KEGG: syc:syc1984_c hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313517.1"
                     /db_xref="GI:150376921"
                     /db_xref="GeneID:5318411"
                     /translation="MPNEIRQRLHGMAVWHDTALDWNNPPGSSPWSKAADVRFAEAVD
                     QLVEDIRRELGPGYEVINEHCSIY"
     gene            complement(1307310..1307501)
                     /locus_tag="Smed_4790"
                     /pseudo
                     /db_xref="GeneID:5318412"
     gene            complement(1307542..1307795)
                     /locus_tag="Smed_4791"
                     /pseudo
                     /db_xref="GeneID:5319020"
     gene            1307932..1309020
                     /locus_tag="Smed_4792"
                     /db_xref="GeneID:5319021"
     CDS             1307932..1309020
                     /locus_tag="Smed_4792"
                     /note="KEGG: nha:Nham_4600 feruloyl esterase"
                     /codon_start=1
                     /transl_table=11
                     /product="feruloyl esterase"
                     /protein_id="YP_001313518.1"
                     /db_xref="GI:150376922"
                     /db_xref="GeneID:5319021"
                     /translation="MANATGRPTPPLVLSEAEREYLERQVRKHRVARSLSERCRIILR
                     CGEGVPSKVVADELGVHEHTVGKWRRRFLKDRLDGLLDEVRPGRPRTIDDDQIAAVIE
                     RTLRSTPSDATHWSIRSMAGATGFSHTTIRRIWNAFGLQPHRTETFKLSSDPLFVDKV
                     RDIVGLYLSPPNRALVLSVDEKSQIQALDREQPVLPMMPGVPERRTHSYVRHGTTTLF
                     AALDVASGFVIGKCYKRHRATEFLDFLKQIDASVPSDLDVHIVMDNYATHKTASVKNW
                     LMRRPRYHVHFTPTSASWINQVERWFAELTRKQLRRGVHTSTMQLEADIRSFIERHNQ
                     NPKPYRWTKSAHDILASVKRFCQKVQDL"
     misc_feature    1308028..1308174
                     /locus_tag="Smed_4792"
                     /note="Homeodomain-like domain; Region: HTH_23; pfam13384"
                     /db_xref="CDD:222091"
     misc_feature    1308043..1308348
                     /locus_tag="Smed_4792"
                     /note="Winged helix-turn helix; Region: HTH_29; pfam13551"
                     /db_xref="CDD:222216"
     misc_feature    1308121..1308336
                     /locus_tag="Smed_4792"
                     /note="Homeodomain-like domain; Region: HTH_32; pfam13565"
                     /db_xref="CDD:222226"
     misc_feature    1308517..1308897
                     /locus_tag="Smed_4792"
                     /note="DDE superfamily endonuclease; Region: DDE_3;
                     pfam13358"
                     /db_xref="CDD:222070"
     misc_feature    1308589..1308966
                     /locus_tag="Smed_4792"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG3335"
                     /db_xref="CDD:225872"
     gene            complement(1309136..1309927)
                     /locus_tag="Smed_4793"
                     /db_xref="GeneID:5319022"
     CDS             complement(1309136..1309927)
                     /locus_tag="Smed_4793"
                     /note="TIGRFAM: glycosyl transferase, WecB/TagA/CpsF
                     family;
                     PFAM: glycosyl transferase WecB/TagA/CpsF;
                     KEGG: mmr:Mmar10_2515 glycosyl transferase, WecB/TagA/CpsF
                     family"
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyl transferase"
                     /protein_id="YP_001313519.1"
                     /db_xref="GI:150376923"
                     /db_xref="InterPro:IPR004629"
                     /db_xref="GeneID:5319022"
                     /translation="MADLAPWSMGEAYCADRRHYFLGAPFDGIRKEAVLSLLDNCSSH
                     ARFRYVVTPNVDHVVRLNGNAGLAPYYDQAWLSLCDSRPISRLARLLLLDLPLVTGSD
                     LTAALFSSVIRDGEKITLIAANAEIVRAMERAYPRVCFRAKVPPEAVYSNPAASMDCV
                     DFATREEARFVFIAIGSPQSEKIAHAIMAHPEGRGVGFCVGASLEFLTGAKRRAPIWM
                     RHAGLEWLHRLASDPRRLWRRYVFAVVPLIRLFAGEIARRHHGAG"
     misc_feature    complement(1309166..1309867)
                     /locus_tag="Smed_4793"
                     /note="Teichoic acid biosynthesis proteins [Cell envelope
                     biogenesis, outer membrane]; Region: WecG; COG1922"
                     /db_xref="CDD:224833"
     misc_feature    complement(1309208..1309717)
                     /locus_tag="Smed_4793"
                     /note="The glycosyltransferase WecG/TagA superfamily
                     contains Escherichia coli WecG, Bacillus subtilis TagA and
                     related proteins. E. coli WecG is believed to be a
                     UDP-N-acetyl-D-mannosaminuronic acid transferase, and is
                     involved in enterobacterial common...; Region:
                     Glyco_transf_WecG_TagA; cd06533"
                     /db_xref="CDD:119439"
     gene            1310194..1311414
                     /locus_tag="Smed_4794"
                     /db_xref="GeneID:5319023"
     CDS             1310194..1311414
                     /locus_tag="Smed_4794"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: pen:PSEEN2450 glycosyl transferase, group 2 family
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313520.1"
                     /db_xref="GI:150376924"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5319023"
                     /translation="MLETFLCYAIFGLSAVLSVPSGIYAVECSIGSLPLQRRRVAEFG
                     LKANAAVTAVLVPAHNEESGIADTLANIGAQLCDQDRLIVVADNCSDRTAALAQEAGA
                     EVIERFDVDRRGKGYALDAGIRHLEKMPPEIVVLMDADCRLGEKALERLRASVLASGM
                     PGQSRNLMTAPDGAAPNLLVAEFAFLVKNYVRPLGLVRMNLPCHATGTGLAIPWHALR
                     GADVAHAHRVEDMKLGLDLASAGYAPRFCEEALVTSQFPCSGEGANAQRRRWEGGHLE
                     MIRSELRSLVNPLVLRNPARLALALDLMVPPLTLLVLLLASVMLLSVMLAASGLSSWP
                     LVIATVNLALVFVATLGAWYVHGRKALPAATISRIPLYVLWKLRLYPRALLGANEGWV
                     RTDRDKDVSGESRT"
     sig_peptide     1310194..1310271
                     /locus_tag="Smed_4794"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.618) with cleavage site probability 0.602 at
                     residue 26"
     misc_feature    1310350..1311012
                     /locus_tag="Smed_4794"
                     /note="Glycosyltransferase like family 2; Region:
                     Glyco_tranf_2_3; pfam13641"
                     /db_xref="CDD:222281"
     misc_feature    1310353..1310892
                     /locus_tag="Smed_4794"
                     /note="EpsO protein participates in the methanolan
                     synthesis; Region: EpsO_like; cd06438"
                     /db_xref="CDD:133060"
     misc_feature    1310605..1310613
                     /locus_tag="Smed_4794"
                     /note="DXD motif; other site"
                     /db_xref="CDD:133060"
     gene            complement(1311520..1312950)
                     /locus_tag="Smed_4795"
                     /db_xref="GeneID:5319024"
     CDS             complement(1311520..1312950)
                     /locus_tag="Smed_4795"
                     /EC_number="2.7.7.22"
                     /note="TIGRFAM: mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase;
                     PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl
                     transferase; Cupin 2 conserved barrel domain protein;
                     KEGG: ret:RHE_CH03244 mannose-1-phosphate
                     guanylyltransferase (GDP) protein"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="YP_001313521.1"
                     /db_xref="GI:150376925"
                     /db_xref="InterPro:IPR001538"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR006375"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="InterPro:IPR013794"
                     /db_xref="GeneID:5319024"
                     /translation="MTRRIVPVIMAGGKGTRLWPLSRSAAPKQFMQFVNDYTLFQSTL
                     LRVSDQTVYEPAVVITNESFHVLVTEQAREMGVALSAIVLEPVPRNTAAAVAAAALVI
                     SRLFKEDRTIHVLASDHDINVDDSYHEAHLIARLEAADGKLATFGITPTEPAIGYGYI
                     EVGEALASGAYKVSRFVEKPAFKNALEMLSAGGFYWNSGIFMFSLSTVLVEIAEHAPE
                     VLKAVNLAVSKSVADHDCVLLDTDAFERCPDISFDYAVMEKTSRAVVVPSAFGWSDLG
                     SWDAVWKTGRHDENHNVASAHTTLTDTRNSLIMTQGAHLAVHGLEGIAVIASEDAVYV
                     GRLHDSQNVRKVVSLLAAAPETARLTELHPTTCRPWGDCTTILNGEHFQVRRITVRPG
                     KRLSLQRHRHRCEHWIVIKGTAEVTIANRVQILNENESVCVATGEEHRLANPGNTVTE
                     LIEIQTGSYLGDDDIVRASDGVERVE"
     misc_feature    complement(1311541..1312938)
                     /locus_tag="Smed_4795"
                     /note="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase; Region:
                     GMP_PMI; TIGR01479"
                     /db_xref="CDD:233431"
     misc_feature    complement(1312108..1312938)
                     /locus_tag="Smed_4795"
                     /note="GDP-M1P_Guanylyltransferase catalyzes the formation
                     of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase;
                     cd02509"
                     /db_xref="CDD:133003"
     misc_feature    complement(order(1312597..1312599,1312915..1312917,
                     1312921..1312923))
                     /locus_tag="Smed_4795"
                     /note="Substrate binding site; other site"
                     /db_xref="CDD:133003"
     misc_feature    complement(1311541..1311996)
                     /locus_tag="Smed_4795"
                     /note="Cupin domain; Region: Cupin_2; cl17218"
                     /db_xref="CDD:247772"
     gene            complement(1312947..1314446)
                     /locus_tag="Smed_4796"
                     /db_xref="GeneID:5319025"
     CDS             complement(1312947..1314446)
                     /locus_tag="Smed_4796"
                     /note="PFAM: phosphoglucomutase/phosphomannomutase ;
                     phosphoglucomutase/phosphomannomutase alpha/beta/alpha
                     domain I; phosphoglucomutase/phosphomannomutase
                     alpha/beta/alpha domain II;
                     phosphoglucomutase/phosphomannomutase alpha/beta/alpha
                     domain III;
                     KEGG: rle:RL3674 putative phosphomannomutase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucomutase/phosphomannomutase
                     alpha/beta/subunit"
                     /protein_id="YP_001313522.1"
                     /db_xref="GI:150376926"
                     /db_xref="InterPro:IPR005843"
                     /db_xref="InterPro:IPR005844"
                     /db_xref="InterPro:IPR005845"
                     /db_xref="InterPro:IPR005846"
                     /db_xref="GeneID:5319025"
                     /translation="MRGNRSQLKKLDDMKFGTSGLRGLSVDLVEVGARAYAGAFGRYL
                     VELGKVRTGDAILIGNDLRDSSPEIKMICATVLERLGFRVADCGTVPTPALAFYASKL
                     EAAGLMVTGSHIAADRNGIKFYCPNGEINKADETAIAALAADYRSQSDVPRDNTVLPL
                     EDHAERCLRLFYERNARLLSGGALAGLKVGVYEHSSVARDLIAMLLLRLGADVVPLGR
                     SEIFIPVDTEALSPQTIISLEEWAGSHGLDAVVSADGDGDRPLIADEMGRPLRGDLIG
                     LMTARFLGAKTIVTPITSNSGIEALGFFSVIRTKVGSPFVIAAMQQASAASGDPVIGF
                     EANGGVLTASTIDLGRYRLEALPTRDCILPILAVLSQVKSQGRPLSVVARSYHLPAAA
                     AGRLENYPVEASTALMSYLRSFENISVFLRDVGQVTSANDIDGLRVTLTERRTIHFRP
                     SGNAPELRCYAEAATETAAWDLLNAGLARLRLWTNEFSKQQAAHEDILN"
     misc_feature    complement(1312998..1314422)
                     /locus_tag="Smed_4796"
                     /note="Phosphomannomutase [Carbohydrate transport and
                     metabolism]; Region: {ManB}; COG1109"
                     /db_xref="CDD:224034"
     misc_feature    complement(1313016..1314404)
                     /locus_tag="Smed_4796"
                     /note="ManB is a bacterial phosphomannomutase (PMM) that
                     catalyzes the conversion of mannose 6-phosphate to
                     mannose-1-phosphate in the second of three steps in the
                     GDP-mannose pathway, in which GDP-D-mannose is synthesized
                     from fructose-6-phosphate. In...; Region: ManB; cd03088"
                     /db_xref="CDD:100090"
     misc_feature    complement(order(1313073..1313075,1313088..1313096,
                     1313100..1313102,1313430..1313432,1313436..1313438,
                     1313442..1313444,1313508..1313516,1313568..1313570,
                     1313670..1313675,1313679..1313681,1313685..1313687,
                     1314081..1314083,1314105..1314113,1314381..1314383,
                     1314390..1314392,1314396..1314398))
                     /locus_tag="Smed_4796"
                     /note="active site"
                     /db_xref="CDD:100090"
     misc_feature    complement(order(1313073..1313075,1313088..1313096,
                     1313100..1313102,1313430..1313432,1313436..1313438,
                     1313442..1313444,1313508..1313510,1313514..1313516,
                     1313568..1313570,1313670..1313672,1314111..1314113,
                     1314390..1314392))
                     /locus_tag="Smed_4796"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100090"
     misc_feature    complement(order(1313673..1313675,1313679..1313681,
                     1313685..1313687,1314111..1314113))
                     /locus_tag="Smed_4796"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:100090"
     gene            1314819..1315694
                     /locus_tag="Smed_4797"
                     /db_xref="GeneID:5319026"
     CDS             1314819..1315694
                     /locus_tag="Smed_4797"
                     /note="KEGG: aau:AAur_2156 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313523.1"
                     /db_xref="GI:150376927"
                     /db_xref="GeneID:5319026"
                     /translation="MTSLSVVTPSYRPDLELCRDLNLSVRRFGPSGVAHHVIVPAADR
                     KAFAGIGDVHAVDGYLPRSFVHIPGNLWVNLRSPILPVRGWIAQQLIKLEFVARSQDS
                     VVLLVDSDVTFIRPFSADTFHRHGEVRFFRAVDAIHAGLPRHICWHRVARELLGVRSC
                     DRMPLNDYICWPMAWDPSVVRSMLRRVEEVTGKPWQTAVASQRHFSEGILYGVYVDEI
                     LGGMPYSENTMLCVNYYDETPFEEIEKFASYITPNDIAVMISAKSGTSLASRRRALAA
                     IAASVGADIHQQGAT"
     gene            complement(1315756..1316946)
                     /locus_tag="Smed_4798"
                     /db_xref="GeneID:5319027"
     CDS             complement(1315756..1316946)
                     /locus_tag="Smed_4798"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313524.1"
                     /db_xref="GI:150376928"
                     /db_xref="GeneID:5319027"
                     /translation="MPVRRRQFLRLASLLPFTEAACGLSIPGAIAAEARSFHGNLPPF
                     FITGIWQQPIEKIALWKARGVNTLFAVNGGGDVTQWTNEANRQGVYMVREPRGIDVSG
                     ASFLVADRAAFELDLTEPGLLAFSLMDEPSNLKPEGKDITYEEVLLKPDEIDVIARDW
                     SLGGKALWINHVGNHINNVHLDGIMSDYADSQYIDWLSHDCYPIASGDTLLLELNGYT
                     STHQGHAIDRISRWSGDKPQFSFVGLTQYNGEVGREPTPAEFRAQAWSSIIHGATGLI
                     YFSFKFSPEFSYDDARPEILREMAVLHAQIDQIHDILMDDAKGGRRPSRLLKSESGWG
                     ASGLPFPFEGCEIQTGRGAYKIVLNLLDDTAELTYSPWDLSGVRFDPYQCRLGFVAAE
                     MASE"
     sig_peptide     complement(1316851..1316946)
                     /locus_tag="Smed_4798"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.760) with cleavage site probability 0.605 at
                     residue 32"
     gene            1317154..1318698
                     /locus_tag="Smed_4799"
                     /db_xref="GeneID:5319028"
     CDS             1317154..1318698
                     /locus_tag="Smed_4799"
                     /note="KEGG: nar:Saro_3228 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313525.1"
                     /db_xref="GI:150376929"
                     /db_xref="GeneID:5319028"
                     /translation="MARARGHRVRKVSRSASGPVQPLSGFPASSGSERWPKFETSAMS
                     IIASRAGEAGAKGKTALNRLLIILFVTAIAVPWIIPVGALRMSAYRMTLCIVVIPCLV
                     HWLSGRAGPIRFSDFAIILFAFWKGLSLAVLHGEEAVQAIGISFVETLGPYFLARCCV
                     RSAEDFEVFAKALFVVIAALLPLILLETVTGWKATLRIFAFVLPTYPDDPMMRAGFWR
                     AQGPFEHPILCGVVCSVGFVLAFLVLGYARPPLDRYSKAGTIAFTVALSLSAGPLLGI
                     ALQSLLIAWKRLADAIGPRPLWLMTVTLSALALCTSWITGRSLVALVGRLTFDPMSYW
                     SRNLIWEVGWVSVSNHPAFGTGLGRWDRPEWMVSSIDNFWLSTAVTHGLPALLFIIAS
                     VAICLVAVGRKTGLHEKLREYRSAYVISVFSWCAVGQTVHLWDGALVIVLFLLGSGLW
                     LLDVDANEAHPYPASDRLRRKRIDSVGVRRPGHRRPPRGSRRSPNLAEHRFGATIPKH
                     YPGPSE"
     misc_feature    1317922..1318326
                     /locus_tag="Smed_4799"
                     /note="O-antigen ligase like membrane protein; Region:
                     O-antigen_lig; pfam13425"
                     /db_xref="CDD:222119"
     gene            1318973..1319653
                     /locus_tag="Smed_4800"
                     /db_xref="GeneID:5319029"
     CDS             1318973..1319653
                     /locus_tag="Smed_4800"
                     /EC_number="2.7.8.6"
                     /note="PFAM: sugar transferase;
                     KEGG: pde:Pden_0842 undecaprenyl-phosphate galactose
                     phosphotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate galactose
                     phosphotransferase"
                     /protein_id="YP_001313526.1"
                     /db_xref="GI:150376930"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="GeneID:5319029"
                     /translation="MWRNPKLGPQLFATLPAPYDETLRSRSSYLKAKRGFDILVTLLI
                     GPLILAIVTVLALLVRLDGEKAFYFQPRLGKGGGVFCLWKLRTMVPDSERKLQEYFEA
                     DPAARSEWDRTQKLRNDPRVTRLGKYLRKYSADELPQLLNVLIGDMSLVGPRPILPEQ
                     RRHYPGTAYFTMRPGLTGLWQINERNSCTFAERAAYDTRYAGLMSFSADLLILLKTVL
                     VVLRGTGI"
     misc_feature    1319069..1319599
                     /locus_tag="Smed_4800"
                     /note="Bacterial sugar transferase; Region: Bac_transf;
                     pfam02397"
                     /db_xref="CDD:217016"
     gene            complement(1319691..1320470)
                     /locus_tag="Smed_4801"
                     /db_xref="GeneID:5319030"
     CDS             complement(1319691..1320470)
                     /locus_tag="Smed_4801"
                     /note="PFAM: regulatory protein LuxR;
                     KEGG: rle:pRL90149 putative transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="two component LuxR family transcriptional
                     regulator"
                     /protein_id="YP_001313527.1"
                     /db_xref="GI:150376931"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="GeneID:5319030"
                     /translation="MASDMIGENEINHDRIDHIVAARDSAGATDNHERLLVIIDSRAL
                     DRQCLAQSIIAHNMDMQVLALGTMVDWGQHRNNYPAPSAILLNVGARRIAEPFITAEI
                     RELSSEFATTPVIVLADTDELAQVVKALEYGAKGYIPSSVSIDVCIEAIGLALAGGIF
                     VPASSILAMGRLLETGNAVAHPLAGMFTARQAEVVEALRRGKANKIIAYELNLRESTV
                     KVHIRNIMKKVKATNRTEVAFKINDLFPADTPVDGTNWLDP"
     misc_feature    complement(1319757..1320365)
                     /locus_tag="Smed_4801"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    complement(1320006..>1320167)
                     /locus_tag="Smed_4801"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cl17736"
                     /db_xref="CDD:248290"
     misc_feature    complement(order(1320048..1320053,1320060..1320062,
                     1320117..1320119))
                     /locus_tag="Smed_4801"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    complement(1320045..1320053)
                     /locus_tag="Smed_4801"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     misc_feature    complement(1319742..1319912)
                     /locus_tag="Smed_4801"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(1319769..1319771,1319802..1319816,
                     1319820..1319825,1319829..1319834,1319856..1319864,
                     1319901..1319909))
                     /locus_tag="Smed_4801"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    complement(order(1319742..1319747,1319754..1319756,
                     1319763..1319771,1319862..1319864,1319868..1319870,
                     1319874..1319876))
                     /locus_tag="Smed_4801"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(1321175..1322296)
                     /locus_tag="Smed_4802"
                     /db_xref="GeneID:5318689"
     CDS             complement(1321175..1322296)
                     /locus_tag="Smed_4802"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: aau:AAur_2155 putative glycosyl transferase /
                     polysaccharide biosynthesis domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313528.1"
                     /db_xref="GI:150376932"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318689"
                     /translation="MDILTRTAAKLANGRIEEPRALNRIARVTVVVPCYNYGRYLRQC
                     VESVTLNQPGVDVEVIIVDDRSTDDSAYVARSIQDADKRVHLIAHKQNKGHIATYNDG
                     LEAATGEFVLLLSADDLVTPGALTRAAEFLAAEPSVGLVYGNAIHFHGELPESRIAGG
                     SWIVWPGVDWLRIRCRSGFNTITSPEAVMRTAVLREIGNYRADLPHAGDFEMWLRTSA
                     VSDIGFLAGVDQAYYRHHATNMNKQDFGSGTALGQLIDLKQRWQSFEAVFSGVGSGLE
                     EGPQLLELARSTIARQVLERINYAHAKGWRDFPTTEFEALAREIHHSPASTRAGKVLA
                     KRRHDGTGRLPAHALWPAWAVRWRLEEWCRRWRRGQIGV"
     misc_feature    complement(<1321661..1322218)
                     /locus_tag="Smed_4802"
                     /note="Glycosyltransferases involved in cell wall
                     biogenesis [Cell envelope biogenesis, outer membrane];
                     Region: WcaA; COG0463"
                     /db_xref="CDD:223539"
     misc_feature    complement(1321703..1322212)
                     /locus_tag="Smed_4802"
                     /note="Glycosyl transferase family 2; Region:
                     Glycos_transf_2; pfam00535"
                     /db_xref="CDD:215980"
     misc_feature    complement(order(1321946..1321948,1321952..1321954,
                     1322111..1322113,1322192..1322194,1322198..1322200))
                     /locus_tag="Smed_4802"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            complement(1322312..1323628)
                     /locus_tag="Smed_4803"
                     /db_xref="GeneID:5318690"
     CDS             complement(1322312..1323628)
                     /locus_tag="Smed_4803"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: lxx:Lxx04950 glycosyl transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313529.1"
                     /db_xref="GI:150376933"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318690"
                     /translation="MGGRSSLQREIFSMSATMKEGFALCGAAASVFREIPRQFGRRTR
                     QISHIVATTGFQGVICRARFKASDWIRPREPVWPVVPDDIIAADLSQPFCARVPEIDR
                     EAPITVNWVTGPAGRGSGGHTTLYRIVKQLQNSGYLNRVYLYDPYAGDPKYYQGLARE
                     HYGLTCEIGDIRDGMKDADALVATSWPTAYAVFNARCAGKRFYFVQDYEPYFYPVGTN
                     SVLAENTYRMGFHGITAGRWLAEKLAREFGMQSDYFPFGCDTALYRRDPASKRSGVAF
                     YARVGTPRRAVELGLLALELFAKRQPQIELHLFGERFDNLPFRVTNHGLVSPQRLNEI
                     YNRCFAGLSLSLTNVSLVPQEMLASGCLPVVNDAVQNRIVLDNSYVRYAPLTPHLLAA
                     ALESVVSMPDFASVSKKASESVAPTSWNMAGAAVDRAFRVALRQAL"
     misc_feature    complement(<1323068..1323253)
                     /locus_tag="Smed_4803"
                     /note="UDP-glucose/GDP-mannose dehydrogenase family, UDP
                     binding domain; Region: UDPG_MGDP_dh_C; cl17747"
                     /db_xref="CDD:248301"
     misc_feature    complement(<1322534..>1322920)
                     /locus_tag="Smed_4803"
                     /note="Glycosyltransferases catalyze the transfer of sugar
                     moieties from activated donor molecules to specific
                     acceptor molecules, forming glycosidic bonds. The acceptor
                     molecule can be a lipid, a protein, a heterocyclic
                     compound, or another carbohydrate...; Region:
                     Glycosyltransferase_GTB_type; cl10013"
                     /db_xref="CDD:245227"
     gene            1324015..1324515
                     /locus_tag="Smed_4804"
                     /db_xref="GeneID:5318691"
     CDS             1324015..1324515
                     /locus_tag="Smed_4804"
                     /note="PFAM: transferase hexapeptide repeat containing
                     protein;
                     KEGG: rle:pRL90150 putative hexapeptide repeat
                     acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hexapaptide repeat-containing transferase"
                     /protein_id="YP_001313530.1"
                     /db_xref="GI:150376934"
                     /db_xref="InterPro:IPR001451"
                     /db_xref="GeneID:5318691"
                     /translation="MIANDVTLHDGVVVHHPDLVNLYGCTIGSGTRIGTFVEIQKNTT
                     IGRNCKISSHSFLCEGVTLEDGVFIGHGVMFTNDLYPRAINADGGRQSEGDWTVVPTR
                     VKQRVSIGSNATILAGITIGESAQVGAGAVVTRDVPAYTIVAGVPARMIGHTKDAAVN
                     TVRAGA"
     misc_feature    1324093..1324470
                     /locus_tag="Smed_4804"
                     /note="WcxM-like, Left-handed parallel beta-Helix (LbH)
                     N-terminal domain: This group is composed of Xanthomonas
                     campestris WcxM and proteins with similarity to the WcxM
                     N-terminal domain. WcxM is thought to be bifunctional,
                     catalyzing both the isomerization...; Region:
                     LbH_WxcM_N_like; cd03358"
                     /db_xref="CDD:100048"
     misc_feature    order(1324156..1324158,1324162..1324164,1324186..1324188,
                     1324210..1324212,1324216..1324218,1324234..1324236,
                     1324252..1324260,1324330..1324332,1324336..1324338,
                     1324345..1324347,1324402..1324404,1324450..1324452)
                     /locus_tag="Smed_4804"
                     /note="putative trimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:100048"
     misc_feature    order(1324162..1324164,1324168..1324170,1324252..1324254,
                     1324258..1324260,1324336..1324338,1324342..1324347,
                     1324360..1324362,1324396..1324401,1324414..1324419,
                     1324444..1324449,1324453..1324455)
                     /locus_tag="Smed_4804"
                     /note="putative active site [active]"
                     /db_xref="CDD:100048"
     misc_feature    order(1324162..1324164,1324168..1324170,1324252..1324254)
                     /locus_tag="Smed_4804"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:100048"
     misc_feature    order(1324252..1324254,1324258..1324260,1324336..1324338,
                     1324342..1324347,1324360..1324362,1324390..1324392,
                     1324396..1324401,1324414..1324419,1324438..1324440,
                     1324444..1324449,1324453..1324455,1324465..1324467)
                     /locus_tag="Smed_4804"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100048"
     gene            1324517..1325542
                     /locus_tag="Smed_4805"
                     /db_xref="GeneID:5318692"
     CDS             1324517..1325542
                     /locus_tag="Smed_4805"
                     /note="PFAM: oxidoreductase domain protein; Oxidoreductase
                     domain; homoserine dehydrogenase NAD-binding;
                     KEGG: rle:pRL90151 putative GFO/IDH/MocA family
                     oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain-containing protein"
                     /protein_id="YP_001313531.1"
                     /db_xref="GI:150376935"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="InterPro:IPR005106"
                     /db_xref="GeneID:5318692"
                     /translation="MIGVAVVGYGYWGPNLVRNFWEIPGACLVAVCDLRKDRLVAVQN
                     RYPAVHVTDDFDELLRNPRIDAIAIATPVAAHFKLAMKTLMAGKHVLVEKPMAASSDE
                     ARRMLEEAARRRLVLAVDHTFVHTGAVRKMRDLVQDGLGDVYYYDSVRVNLGLFQRDV
                     SVIWDLAVHDLSIMDYVLPERPVAVSATGMSHIAGEPANIAYLNLFFESKLIAHIHVN
                     WLAPVKVRRTLVGGSSKMILYDDLEPSEKIKVYDRGVTLNDSGEKVYQMLVGYRTGDM
                     YAPHIDVAEALEIELRQFVECVERNKTPTADGNAGLRVVKILEAASQSLAERGRVVEL
                     EHMRRIA"
     misc_feature    1324517..1325521
                     /locus_tag="Smed_4805"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:223745"
     misc_feature    1324520..1324813
                     /locus_tag="Smed_4805"
                     /note="Oxidoreductase family, NAD-binding Rossmann fold;
                     Region: GFO_IDH_MocA; pfam01408"
                     /db_xref="CDD:201778"
     misc_feature    1324913..1325194
                     /locus_tag="Smed_4805"
                     /note="Oxidoreductase family, C-terminal alpha/beta
                     domain; Region: GFO_IDH_MocA_C; pfam02894"
                     /db_xref="CDD:217272"
     gene            1325539..1326645
                     /locus_tag="Smed_4806"
                     /db_xref="GeneID:5318693"
     CDS             1325539..1326645
                     /locus_tag="Smed_4806"
                     /EC_number="2.6.1.50"
                     /note="PFAM: DegT/DnrJ/EryC1/StrS aminotransferase;
                     aromatic amino acid beta-eliminating lyase/threonine
                     aldolase;
                     KEGG: rle:pRL90152 putative pleiotropic regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--scyllo-inositol transaminase"
                     /protein_id="YP_001313532.1"
                     /db_xref="GI:150376936"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="InterPro:IPR001597"
                     /db_xref="GeneID:5318693"
                     /translation="MIPFLDLRAQYASIKEEIDAAVLRVLASAEYVLGDEVAELEREF
                     SAYCGVRHAVAVNTGTSALHLALLALGAGPGDEVITVPFTFVATVSAIVYTGALPVFV
                     DVEPMTLTMDATKLEAAITPRTKAIVPVHLYGQMADMDAIRAIADRHGISIVEDACQA
                     HGAEYRGRRAGSIGVSGCFSFYPGKNLGACGEGGIVVTSDEGQARTMRMLRDWGQESR
                     YHHVLKGFNYRMDGIQGAILRVKLRHLDAWTRARRARAALYSSLLREANSVRAPIEAA
                     GRSHVYHVYAVRCRDREGLKRALSTQDIQYGLHYPIPVHLQKAHADLGYAEGDFPRSE
                     AAACCVLSLPIYPEMTTGQVEQVVSAMEQKAYVH"
     misc_feature    1325542..1326627
                     /locus_tag="Smed_4806"
                     /note="Predicted pyridoxal phosphate-dependent enzyme
                     apparently involved in regulation of cell wall biogenesis
                     [Cell envelope biogenesis, outer membrane]; Region: WecE;
                     COG0399"
                     /db_xref="CDD:223476"
     misc_feature    1325590..1326618
                     /locus_tag="Smed_4806"
                     /note="3-amino-5-hydroxybenzoic acid synthase family
                     (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate
                     (PLP)-dependent aspartate aminotransferase superfamily
                     (fold I). The members of this CD are involved in various
                     biosynthetic pathways for secondary...; Region: AHBA_syn;
                     cd00616"
                     /db_xref="CDD:99740"
     misc_feature    order(1325713..1325718,1326004..1326006,1326013..1326015,
                     1326076..1326078,1326088..1326093,1326463..1326465)
                     /locus_tag="Smed_4806"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99740"
     misc_feature    order(1325713..1325718,1325788..1325790,1326004..1326006,
                     1326013..1326015,1326076..1326078,1326091..1326093)
                     /locus_tag="Smed_4806"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99740"
     misc_feature    1326091..1326093
                     /locus_tag="Smed_4806"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99740"
     gene            1326635..1327336
                     /locus_tag="Smed_4807"
                     /db_xref="GeneID:5318694"
     CDS             1326635..1327336
                     /locus_tag="Smed_4807"
                     /note="KEGG: ret:RHE_CH01366 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313533.1"
                     /db_xref="GI:150376937"
                     /db_xref="InterPro:IPR001451"
                     /db_xref="GeneID:5318694"
                     /translation="MSTERLPKSRVVPAVHGSRRASGDPGYMVELAGVLGQAYGLGGL
                     IELYGRFMTGDGLVDALMRHVIWRSVVRRCGSGLQVGSGAEFKHPETFEIGNGVFIGA
                     QAYIQGRHDGRCVIGDNVWIGPQAYLDARDLILEDYVGWGPGAKVLGSSHTGTPVDVP
                     IILTDLEIKPVRVCAWADIGTNATILPGVTIGKGALVGAGAVVVRDVEPFAVVAGVPA
                     KFLHWRADAAVPTKS"
     misc_feature    1326914..1327297
                     /locus_tag="Smed_4807"
                     /note="Left-handed parallel beta-Helix (LbetaH or LbH)
                     domain: The alignment contains 5 turns, each containing
                     three imperfect tandem repeats of a hexapeptide repeat
                     motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing
                     hexapeptide repeats are often enzymes...; Region: LbetaH;
                     cl00160"
                     /db_xref="CDD:193687"
     misc_feature    order(1326995..1326997,1327001..1327003,1327013..1327015,
                     1327019..1327021,1327052..1327054,1327091..1327093,
                     1327097..1327099,1327166..1327168,1327181..1327186,
                     1327190..1327192,1327220..1327222,1327232..1327234,
                     1327238..1327240,1327244..1327246)
                     /locus_tag="Smed_4807"
                     /note="putative trimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:100038"
     misc_feature    order(1327166..1327168,1327172..1327177,1327190..1327192,
                     1327226..1327228,1327244..1327246)
                     /locus_tag="Smed_4807"
                     /note="putative CoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100038"
     gene            1327359..1328333
                     /locus_tag="Smed_4808"
                     /db_xref="GeneID:5318695"
     CDS             1327359..1328333
                     /locus_tag="Smed_4808"
                     /note="PFAM: NAD-dependent epimerase/dehydratase;
                     short-chain dehydrogenase/reductase SDR; 3-beta
                     hydroxysteroid dehydrogenase/isomerase; polysaccharide
                     biosynthesis protein CapD; dTDP-4-dehydrorhamnose
                     reductase; Male sterility domain;
                     KEGG: ret:RHE_CH01367 probable UDP-glucose 4-epimerase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="YP_001313534.1"
                     /db_xref="GI:150376938"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318695"
                     /translation="MKNKRVLITGGAGLIGSHIADLVALEEPREILVLDNFVRGRRDN
                     LRQALSTGLVRIIEGDIRNRTLLAHSLEGVDIVFHQAAIRITQCAEEPRLAFDVLARG
                     TFDVLEATVAAGVSKVIAASSASVLGLAQCFPTPEEHHPYNNRTIYGAAKAFNEGLLR
                     SFAEMYGLKYVALRYFNVYGPRMDVHGVYTEVLIRWMERIAASRPPVIFGDDGQTLDF
                     VHVRDIARANLMAAKSDVTDEVFNVASGEETSLRALALLLARIMGTSLEPQLEPARKV
                     NAVTRRLADTRKAERLLGFKTQITLEEGLRDLVAWWRREQTCAGGEAA"
     sig_peptide     1327359..1327433
                     /locus_tag="Smed_4808"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.757) with cleavage site probability 0.457 at
                     residue 25"
     misc_feature    1327368..1328306
                     /locus_tag="Smed_4808"
                     /note="Nucleoside-diphosphate-sugar epimerases [Cell
                     envelope biogenesis, outer membrane / Carbohydrate
                     transport and metabolism]; Region: WcaG; COG0451"
                     /db_xref="CDD:223528"
     misc_feature    1327371..1328294
                     /locus_tag="Smed_4808"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; Region:
                     NADB_Rossmann; cl09931"
                     /db_xref="CDD:245206"
     misc_feature    order(1327386..1327388,1327392..1327397,1327401..1327403,
                     1327461..1327469,1327596..1327604,1327719..1327727,
                     1327800..1327802,1327812..1327814,1327881..1327892)
                     /locus_tag="Smed_4808"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:187535"
     misc_feature    order(1327653..1327655,1327725..1327727,1327800..1327802,
                     1327812..1327814)
                     /locus_tag="Smed_4808"
                     /note="active site"
                     /db_xref="CDD:187535"
     gene            1328330..1329523
                     /locus_tag="Smed_4809"
                     /db_xref="GeneID:5318696"
     CDS             1328330..1329523
                     /locus_tag="Smed_4809"
                     /EC_number="2.6.1.50"
                     /note="PFAM: Cys/Met metabolism
                     pyridoxal-phosphate-dependent protein;
                     DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid
                     beta-eliminating lyase/threonine aldolase;
                     KEGG: rle:pRL90155 putative DegT/DnrJ/EryC1/StrS family
                     aminotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--scyllo-inositol transaminase"
                     /protein_id="YP_001313535.1"
                     /db_xref="GI:150376939"
                     /db_xref="InterPro:IPR000277"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="InterPro:IPR001597"
                     /db_xref="GeneID:5318696"
                     /translation="MIAACGQIPVAKPLLGEQEVEAVRRVILSGWVTQGPEVAAFEKE
                     FADYVGAAHACAVSSCTTALHLALSCVGVGVGDEVITASHSFIATANAIRYCGAMPVF
                     VDIEAGGYNIDPDRIEAAITPRTKAILCVHQLGLPCDLRRVVNVGKRYSIPVIEDAAC
                     AAGSEILWYGQWQRIGKPHGDIACFSFHPRKVVTTGDGGMLTTSSEEYDRKLRLWRQH
                     GMSVPDTIRHGAKQVIYEDYPEFGYNYRMTDFQAAIGREQLKRLPELIARRREIAQKY
                     TWHLSRLAGLRTPAEPSWTRSNWQSYCVVLPDRFDQRETMQALLDRGISTRRGVMNIH
                     LEKAYSGSGTYRAATTLTRSVAAQRTSVILPLFAQMTDAELAHITGELSSILGSADPA
                     ASRTV"
     misc_feature    1328351..1329496
                     /locus_tag="Smed_4809"
                     /note="Predicted pyridoxal phosphate-dependent enzyme
                     apparently involved in regulation of cell wall biogenesis
                     [Cell envelope biogenesis, outer membrane]; Region: WecE;
                     COG0399"
                     /db_xref="CDD:223476"
     misc_feature    1328384..1329463
                     /locus_tag="Smed_4809"
                     /note="3-amino-5-hydroxybenzoic acid synthase family
                     (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate
                     (PLP)-dependent aspartate aminotransferase superfamily
                     (fold I). The members of this CD are involved in various
                     biosynthetic pathways for secondary...; Region: AHBA_syn;
                     cd00616"
                     /db_xref="CDD:99740"
     misc_feature    order(1328507..1328512,1328798..1328800,1328807..1328809,
                     1328885..1328887,1328897..1328902,1329314..1329316)
                     /locus_tag="Smed_4809"
                     /note="inhibitor-cofactor binding pocket; inhibition site"
                     /db_xref="CDD:99740"
     misc_feature    order(1328507..1328512,1328582..1328584,1328798..1328800,
                     1328807..1328809,1328885..1328887,1328900..1328902)
                     /locus_tag="Smed_4809"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99740"
     misc_feature    1328900..1328902
                     /locus_tag="Smed_4809"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99740"
     gene            complement(1329561..1331069)
                     /locus_tag="Smed_4810"
                     /db_xref="GeneID:5318697"
     CDS             complement(1329561..1331069)
                     /locus_tag="Smed_4810"
                     /note="PFAM: polysaccharide biosynthesis protein;
                     KEGG: ret:RHE_CH01369 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="YP_001313536.1"
                     /db_xref="GI:150376940"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="GeneID:5318697"
                     /translation="MQSHPRPEEGHSYGQILKSTALIGGSSAVNVVFAIFRNKATALL
                     LGPAGVGLMGLYSSIADIACALAGLGIQASGVRQIAIAVGSGDADAIARTATALRRVS
                     VLLGLVGALLLTALAVPIACFTFGGHGYAGCVTLLSAAIFLRLLADGQTALIQGMRDI
                     ASLARINVLAAFFSTVVTIPLIYFFGASGIVPSLVVVAAASLATSWWYGRRLRVTARP
                     MSTAQLRREVEALLKLGSAFMVSSFLTLGAAYAVRIFVLRAEGLTAAGLYQAAWTLGG
                     LYAGFILQAMGTDFYPRLTAVAEDNGECNRLVNEQAQVSMLLAGPGLIATLTAAPLVV
                     RLLYSPEFYPAVELLRWICMGMMLRIISWPMGFIVLAKGARRAFFWTEVTATVVHVGL
                     AWLCVGVFGSAGAGLAFVGLYVWHGLLIYAIARHLSDFRWSATNRKLALFFLPASGFV
                     FGAFVALPPWPATIFGMLTTALSGAYSLRMLMELVRLPSLPAAVRAWCSRST"
     misc_feature    complement(1329627..1331027)
                     /locus_tag="Smed_4810"
                     /note="Membrane protein involved in the export of
                     O-antigen and teichoic acid [General function prediction
                     only]; Region: RfbX; COG2244"
                     /db_xref="CDD:225153"
     misc_feature    complement(1329795..1331018)
                     /locus_tag="Smed_4810"
                     /note="Uncharacterized subfamily of the multidrug and
                     toxic compound extrusion (MATE) proteins; Region:
                     MATE_like_10; cd13125"
                     /db_xref="CDD:240530"
     gene            complement(1331075..1331995)
                     /locus_tag="Smed_4811"
                     /db_xref="GeneID:5318698"
     CDS             complement(1331075..1331995)
                     /locus_tag="Smed_4811"
                     /EC_number="1.1.1.133"
                     /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase; polysaccharide
                     biosynthesis protein CapD; dTDP-4-dehydrorhamnose
                     reductase; Male sterility domain;
                     KEGG: mlo:mlr7553 dTDP-6-deoxy-L-mannose-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="YP_001313537.1"
                     /db_xref="GI:150376941"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318698"
                     /translation="MKVLATGTTGQVVTCLTEIAVRLGDVELITIGRPEFDLINPVPL
                     REAIVAASPDVVVSAAAYTAVDRAEDEPARARAVNVAGAACVAEAAARLGVPLIHLST
                     DYVFSGDDPGPRKENDQTRPRTLYGASKLDGEKAVASITPRHVILRTSWVYSPFGTNF
                     VRTILRLAKSREILSVVSDQHGNPTSALDLAAAILEIARSRKGDAFGVYHLAGTGGTN
                     WSDFARHILAVSHLNGGPFATIRGIASADYPTRARRPQDSRLCTDKFEGIFGWCLPPW
                     QDSTKLVVRRLLDPDLRLQSVARRPAAGGE"
     misc_feature    complement(1331153..1331992)
                     /locus_tag="Smed_4811"
                     /note="dTDP-6-deoxy-L-lyxo-4-hexulose reductase and
                     related proteins, extended (e) SDRs; Region:
                     dTDP_HR_like_SDR_e; cd05254"
                     /db_xref="CDD:187564"
     misc_feature    complement(1331153..1331989)
                     /locus_tag="Smed_4811"
                     /note="RmlD substrate binding domain; Region:
                     RmlD_sub_bind; pfam04321"
                     /db_xref="CDD:218026"
     misc_feature    complement(order(1331540..1331551,1331606..1331608,
                     1331618..1331620,1331690..1331698,1331762..1331764,
                     1331807..1331809,1331813..1331821,1331879..1331890,
                     1331897..1331902,1331960..1331971,1331975..1331977))
                     /locus_tag="Smed_4811"
                     /note="NADP binding site [chemical binding]; other site"
                     /db_xref="CDD:187564"
     misc_feature    complement(order(1331606..1331608,1331618..1331620,
                     1331690..1331692,1331759..1331761))
                     /locus_tag="Smed_4811"
                     /note="active site"
                     /db_xref="CDD:187564"
     misc_feature    complement(order(1331450..1331452,1331468..1331470,
                     1331504..1331506,1331543..1331545,1331618..1331620,
                     1331690..1331692))
                     /locus_tag="Smed_4811"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:187564"
     gene            complement(1331992..1333059)
                     /locus_tag="Smed_4812"
                     /db_xref="GeneID:5318699"
     CDS             complement(1331992..1333059)
                     /locus_tag="Smed_4812"
                     /note="TIGRFAM: dTDP-glucose 4,6-dehydratase;
                     PFAM: NAD-dependent epimerase/dehydratase; short-chain
                     dehydrogenase/reductase SDR; 3-beta hydroxysteroid
                     dehydrogenase/isomerase; polysaccharide biosynthesis
                     protein CapD; dTDP-4-dehydrorhamnose reductase; Male
                     sterility domain;
                     KEGG: mlo:mlr7552 dTDP-D-glucose-4,6-dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="YP_001313538.1"
                     /db_xref="GI:150376942"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318699"
                     /translation="MNILVTGGAGFIGSALCRHLVADPDNRVVSLDKLTYAGNLASLR
                     QIENLRNYRFVRADICDEGAIASILSAEKIDRIMHLAAETHVDRSIDGPGAFIETNIL
                     GTFRLLQAALHYWRGLCGRAAEAFRFHHVSTDEVFGALSLDDESFNESTPYAPSSPYS
                     ASKAASDHLVRAWHHTFGLPVVLTNCSNNYGPFQFPEKLIPLTILNAMEERPLPVYGN
                     GTNVRDWLYVDDHARALDLVALKGTVSESYNIGGGCERTNLHVVDTICDILDGKRPRR
                     NGKSHRDLIAFVDDRPGHDWRYAMDTSKIERELGLKPRESFETGIERTIDWYLENGWW
                     WQPIRDRNYRGERLGRSVAAP"
     misc_feature    complement(1332013..1333059)
                     /locus_tag="Smed_4812"
                     /note="dTDP-D-glucose 4,6-dehydratase [Cell envelope
                     biogenesis, outer membrane]; Region: RfbB; COG1088"
                     /db_xref="CDD:224013"
     misc_feature    complement(1332061..1333059)
                     /locus_tag="Smed_4812"
                     /note="dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs;
                     Region: dTDP_GD_SDR_e; cd05246"
                     /db_xref="CDD:187557"
     sig_peptide     complement(1332991..1333059)
                     /locus_tag="Smed_4812"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.747) with cleavage site probability 0.742 at
                     residue 23"
     misc_feature    complement(order(1332493..1332504,1332571..1332573,
                     1332583..1332585,1332661..1332669,1332763..1332765,
                     1332808..1332810,1332814..1332822,1332883..1332891,
                     1332946..1332951,1332955..1332966,1333024..1333035,
                     1333039..1333041))
                     /locus_tag="Smed_4812"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187557"
     misc_feature    complement(order(1332166..1332168,1332178..1332180,
                     1332187..1332189,1332286..1332288,1332391..1332393,
                     1332397..1332399,1332412..1332420,1332451..1332456,
                     1332463..1332471,1332496..1332504,1332583..1332585,
                     1332655..1332663,1332802..1332810))
                     /locus_tag="Smed_4812"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187557"
     misc_feature    complement(order(1332175..1332177,1332529..1332537,
                     1332541..1332546,1332553..1332558,1332565..1332570,
                     1332577..1332579,1332586..1332597,1332601..1332606,
                     1332610..1332612,1332643..1332645,1332724..1332726,
                     1332733..1332735,1332745..1332747,1332754..1332759,
                     1332769..1332771,1332778..1332783,1332790..1332792,
                     1332796..1332798))
                     /locus_tag="Smed_4812"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187557"
     misc_feature    complement(order(1332571..1332573,1332583..1332585,
                     1332661..1332663,1332760..1332762))
                     /locus_tag="Smed_4812"
                     /note="active site"
                     /db_xref="CDD:187557"
     gene            complement(1333056..1333637)
                     /locus_tag="Smed_4813"
                     /db_xref="GeneID:5318628"
     CDS             complement(1333056..1333637)
                     /locus_tag="Smed_4813"
                     /EC_number="5.1.3.13"
                     /note="TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase;
                     PFAM: dTDP-4-dehydrorhamnose 35-epimerase related;
                     KEGG: sme:SMb21325 putative dTDP-4-dehydrorhamnose
                     3,5-epimerase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="YP_001313539.1"
                     /db_xref="GI:150376943"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="GeneID:5318628"
                     /translation="MSPEVRALGLDEVLEILPQRIGDERGFFSETWSAVRFGELGLAL
                     TFVQDNHSYSAAKGVLRGLHYQLPPFMQNKLVRVVKGAVFDVAVDIRRGSPTFAKWVG
                     VEISARKWNQLLIPKGFAHGFVTLEADTEVIYKVTSPYSPAHDRSIRFDDPDIAIAWP
                     VPSTELQLSDKDRTAPLLRQAEVFGVAEGRVRR"
     misc_feature    complement(1333095..1333625)
                     /locus_tag="Smed_4813"
                     /note="dTDP-4-dehydrorhamnose 3,5-epimerase; Region:
                     dTDP_sugar_isom; pfam00908"
                     /db_xref="CDD:144487"
     gene            complement(1333634..1334512)
                     /locus_tag="Smed_4814"
                     /db_xref="GeneID:5318629"
     CDS             complement(1333634..1334512)
                     /locus_tag="Smed_4814"
                     /note="TIGRFAM: glucose-1-phosphate thymidylyltransferase;
                     PFAM: Nucleotidyl transferase;
                     KEGG: mlo:mlr7550 glucose-1-phosphate
                     thymidylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="YP_001313540.1"
                     /db_xref="GI:150376944"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="GeneID:5318629"
                     /translation="MRGIILAGGNGTRLYPLTIAISKQILPVYDKPMVYYPLSVLMLA
                     GIRDILIISTARDLPCFEALLGDGSAFGLTLSYAEQPHPNGLAEAFIIGRSFIGSGNV
                     AMILGDNIFFGNGLPNVCRQAASRESGACVFAYRVDDPERYGVVTFDQRTGQAKSIEE
                     KPLRPKSNWAVTGLYFYDNEVVDIAASIQPSARGELEITTVNNIYLERDRLHVCQLGR
                     GFAWLDTGTYDSLHDASSFVRTVERRQGVQIACPEEIALEMGWLGPEDVLKRSRMLGS
                     TPYAYYLRRRVEEHVG"
     misc_feature    complement(1333790..1334512)
                     /locus_tag="Smed_4814"
                     /note="G1P_TT_short is the short form of
                     glucose-1-phosphate thymidylyltransferase; Region:
                     G1P_TT_short; cd02538"
                     /db_xref="CDD:133019"
     misc_feature    complement(1333649..1334509)
                     /locus_tag="Smed_4814"
                     /note="glucose-1-phosphate thymidylyltransferase, short
                     form; Region: rmlA; TIGR01207"
                     /db_xref="CDD:130274"
     misc_feature    complement(order(1333916..1333918,1334000..1334002,
                     1334030..1334035,1334081..1334083,1334189..1334191,
                     1334255..1334266,1334273..1334275,1334486..1334491,
                     1334495..1334497))
                     /locus_tag="Smed_4814"
                     /note="substrate binding site; other site"
                     /db_xref="CDD:133019"
     misc_feature    complement(order(1333790..1333795,1333802..1333810,
                     1333817..1333819,1333826..1333831,1333841..1333849,
                     1334084..1334089,1334099..1334110,1334174..1334179,
                     1334333..1334335,1334408..1334410,1334417..1334428,
                     1334432..1334440,1334450..1334455,1334462..1334470,
                     1334477..1334479))
                     /locus_tag="Smed_4814"
                     /note="tetramer interface; other site"
                     /db_xref="CDD:133019"
     gene            complement(1334568..1335872)
                     /locus_tag="Smed_4815"
                     /db_xref="GeneID:5318630"
     CDS             complement(1334568..1335872)
                     /locus_tag="Smed_4815"
                     /note="PFAM: polysaccharide export protein;
                     KEGG: rle:pRL90158 putative exopolysaccharide production
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="YP_001313541.1"
                     /db_xref="GI:150376945"
                     /db_xref="InterPro:IPR003715"
                     /db_xref="GeneID:5318630"
                     /translation="MNASHHAPLLRSTFVAALALLNGALTPNMAAAAAIAPETKIRLK
                     IMQWMPTKGEYIQWALGGDFVVSEGGTVTIPVIGAVTVGDLDEARLAAEIARRLQAKL
                     GLMEAPEASIEVVEYPPVYVLGDVTKPGKYEFRPGLTALQALAMSGGELRQANPTQSQ
                     DRMKLIGDLKSVDLALLRSNARIARLQAEVSGVKEVHFPEPIGADASHVTEIQNQERI
                     IFSTRANVLTRQSKSLDELRNLLDQEIRVLEEKVNGSDASIRAADQELKGVRSLVERG
                     VAVASRQSDLERELAGYHASRLDFITAIMRARQEISGTTRSLEGLYDNRHAEVASELQ
                     AEQAALEQLKLKRVTTEKQLLDMLAADDNSPPPGEEASPSFKIIRRGDEKTDEVRASG
                     STMLRPGDVIRIVRPARQDPAISAGPLSSPLSTSSQPDRVSQ"
     sig_peptide     complement(1335774..1335872)
                     /locus_tag="Smed_4815"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.563 at
                     residue 33"
     misc_feature    complement(<1335399..1335515)
                     /locus_tag="Smed_4815"
                     /note="SLBB domain; Region: SLBB; pfam10531"
                     /db_xref="CDD:220798"
     gene            1336350..1337096
                     /locus_tag="Smed_4816"
                     /db_xref="GeneID:5318631"
     CDS             1336350..1337096
                     /locus_tag="Smed_4816"
                     /note="PFAM: regulatory protein LuxR;
                     KEGG: atc:AGR_L_3006 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver protein"
                     /protein_id="YP_001313542.1"
                     /db_xref="GI:150376946"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="GeneID:5318631"
                     /translation="MNRRDHDEAHADSATQTAKLREPRRIILMITDFGTVSERLIHAL
                     EREFPWVVIEQVEHVAAACKVFFHPVSLILVGPRLLDEAEARAAELLRLHPQALAAVI
                     ELSDDDLLLSSANVSRSPLVRSLLPMNLRLDVWLSVVRLMLCGGEYLPPALILRSRQN
                     GHSAVPPLENGARATLVASADPRMAGLTARELQILEMVSRGLQNKIIAAEIRLSENTV
                     KIHLHNIITKLGAHNRTEAAARFRSLQERH"
     misc_feature    <1336725..1337081
                     /locus_tag="Smed_4816"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    1336908..1337078
                     /locus_tag="Smed_4816"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    order(1336911..1336919,1336956..1336964,1336986..1336991,
                     1336995..1337000,1337004..1337018,1337049..1337051)
                     /locus_tag="Smed_4816"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    order(1336944..1336946,1336950..1336952,1336956..1336958,
                     1337049..1337057,1337064..1337066,1337073..1337078)
                     /locus_tag="Smed_4816"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(1337205..1337843)
                     /locus_tag="Smed_4817"
                     /db_xref="GeneID:5318632"
     CDS             complement(1337205..1337843)
                     /locus_tag="Smed_4817"
                     /note="KEGG: bms:BRA0772 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313543.1"
                     /db_xref="GI:150376947"
                     /db_xref="GeneID:5318632"
                     /translation="MCLLRGTAILTSKGETVIEDLRMGDLVKTVRGELLPVIWMGRHV
                     YRRTSPTWNDSVVPIRIRRFALDKQTPRKDLYLSSGHALYVDGVFIRPKDLINGTSVA
                     PALPGKLDVLEFYHIVLATHEAVLAEGAPVETFLVEGSNYEEFTNGAEYARLYPAGEH
                     SSMKPFAKTVGYGGREHLNALMRLATRQLVRPRSPLEDVYIRVVTRSAELAL"
     misc_feature    complement(1337436..1337840)
                     /locus_tag="Smed_4817"
                     /note="Hint domain; Region: Hint_2; pfam13403"
                     /db_xref="CDD:222106"
     gene            complement(1338219..1338354)
                     /locus_tag="Smed_4818"
                     /pseudo
                     /db_xref="GeneID:5318633"
     gene            complement(1338517..1338879)
                     /locus_tag="Smed_4819"
                     /pseudo
                     /db_xref="GeneID:5318634"
     gene            complement(1339017..1339759)
                     /locus_tag="Smed_4820"
                     /pseudo
                     /db_xref="GeneID:5318635"
     gene            complement(1339752..1340657)
                     /locus_tag="Smed_4821"
                     /pseudo
                     /db_xref="GeneID:5318636"
     gene            1340802..1341533
                     /locus_tag="Smed_4822"
                     /db_xref="GeneID:5318637"
     CDS             1340802..1341533
                     /locus_tag="Smed_4822"
                     /note="PFAM: cyclic nucleotide-binding;
                     KEGG: sme:SMb21079 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding protein"
                     /protein_id="YP_001313544.1"
                     /db_xref="GI:150376948"
                     /db_xref="InterPro:IPR000595"
                     /db_xref="InterPro:IPR012318"
                     /db_xref="GeneID:5318637"
                     /translation="MTVASEAFARVLETSILRLALDDSDKSHLGSLGFIPRRYPAHAV
                     ITRQGDEEDRIFVVHSGWGCICTNLINGERQILDFPLKGEVVASRAFEGEGLESFTAH
                     TEVMLFEAPAKSISAGLAHSTSLAAGLLGAIAREKAILSQHLTNLGRRSALVRTAHFL
                     LELGTRLEKAEAAKSHGFECPLTQYDLAAALGITAIHVNRMLRELRQRRYVDFRQGSV
                     RLLNKEGLEHFADFDPGYLRLPGET"
     misc_feature    1340856..1341473
                     /locus_tag="Smed_4822"
                     /note="cAMP-binding proteins - catabolite gene activator
                     and regulatory subunit of cAMP-dependent protein kinases
                     [Signal transduction mechanisms]; Region: Crp; COG0664"
                     /db_xref="CDD:223736"
     misc_feature    1340859..1341191
                     /locus_tag="Smed_4822"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; Region: CAP_ED;
                     cd00038"
                     /db_xref="CDD:237999"
     misc_feature    order(1341060..1341065,1341090..1341098)
                     /locus_tag="Smed_4822"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:237999"
     misc_feature    order(1341150..1341158,1341168..1341176)
                     /locus_tag="Smed_4822"
                     /note="flexible hinge region; other site"
                     /db_xref="CDD:237999"
     misc_feature    1341264..1341488
                     /locus_tag="Smed_4822"
                     /note="Crp-like helix-turn-helix domain; Region:
                     HTH_Crp_2; pfam13545"
                     /db_xref="CDD:222212"
     gene            1341717..1342001
                     /locus_tag="Smed_4823"
                     /pseudo
                     /db_xref="GeneID:5318638"
     gene            1341998..1342252
                     /locus_tag="Smed_4824"
                     /pseudo
                     /db_xref="GeneID:5318957"
     gene            1342428..1342667
                     /locus_tag="Smed_4825"
                     /db_xref="GeneID:5318958"
     CDS             1342428..1342667
                     /locus_tag="Smed_4825"
                     /note="KEGG: sme:SMc03284 hypothetical/unknown protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313545.1"
                     /db_xref="GI:150376949"
                     /db_xref="GeneID:5318958"
                     /translation="MIRPLMPWTWDVCFLMGTGFAPKLWRPVIRGHAATGDIIAPIRK
                     VSETKGPATHKDAAAVAEALVNIRSYFMPRRKQKF"
     gene            1343016..1343819
                     /locus_tag="Smed_4826"
                     /db_xref="GeneID:5318959"
     CDS             1343016..1343819
                     /locus_tag="Smed_4826"
                     /note="PFAM: regulatory protein LuxR;
                     KEGG: sme:SMb21080 putative response regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="two component LuxR family transcriptional
                     regulator"
                     /protein_id="YP_001313546.1"
                     /db_xref="GI:150376950"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="GeneID:5318959"
                     /translation="MHSLTRIHENAALEVHRLSSSGPGKATSETHNNTAASSALLLLD
                     NRTLDRECLSQCLVLHGMGMQVLAYGSIDEWRKDKELHPPIAAILLNIGGRKAVDTSN
                     AAEISDLVREFDPTPVVLLSDWDELPQILRALECGVRGYIPSSIGFDVCVQAVNLARA
                     GGIFVPASSVLTTRIDIVAGGEVSRPMTGMFTQRQEEVIQALRRGKANKIIAYELNLR
                     ESTVKVHIRNIMKKLKATNRTEVAYKLSDMFVAEGGARDKPGLPQSGSC"
     misc_feature    1343145..1343774
                     /locus_tag="Smed_4826"
                     /note="Response regulator containing a CheY-like receiver
                     domain and an HTH DNA-binding domain [Signal transduction
                     mechanisms / Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     misc_feature    1343586..1343735
                     /locus_tag="Smed_4826"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    order(1343589..1343597,1343634..1343642,1343664..1343669,
                     1343673..1343678,1343682..1343696,1343727..1343729)
                     /locus_tag="Smed_4826"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    order(1343622..1343624,1343628..1343630,1343634..1343636,
                     1343727..1343735)
                     /locus_tag="Smed_4826"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     gene            complement(1344001..1344258)
                     /locus_tag="Smed_4827"
                     /db_xref="GeneID:5318960"
     CDS             complement(1344001..1344258)
                     /locus_tag="Smed_4827"
                     /note="KEGG: sme:SMc00940 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313547.1"
                     /db_xref="GI:150376951"
                     /db_xref="GeneID:5318960"
                     /translation="MEPYRLRLVQIATRKEYGNTAMSDGKLAEQQTSSRRTAVPPEVD
                     FEPVPLPDQADEPGTRDADAPSARSDPSTNREKKTEGAGKD"
     gene            complement(1344443..1344718)
                     /locus_tag="Smed_4828"
                     /db_xref="GeneID:5318961"
     CDS             complement(1344443..1344718)
                     /locus_tag="Smed_4828"
                     /note="KEGG: sme:SMc02316 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313548.1"
                     /db_xref="GI:150376952"
                     /db_xref="GeneID:5318961"
                     /translation="MEEHRKVNSPAEEDRREVSKACGRFAAITPPAVTMLLSTSLTSA
                     AIAASGGGSNVGKGGRGGNSAKGGKGGNGTKGGKGGNNAKGKAKPGK"
     gene            complement(1344843..1345037)
                     /locus_tag="Smed_4829"
                     /db_xref="GeneID:5318962"
     CDS             complement(1344843..1345037)
                     /locus_tag="Smed_4829"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313549.1"
                     /db_xref="GI:150376953"
                     /db_xref="GeneID:5318962"
                     /translation="MRDRDDFGLPEQRASTGLPLSIVLLSVLTIAAYLMIGDALSNRE
                     SRGVAVYTSNFHSNQSNASE"
     gene            1345338..1345733
                     /locus_tag="Smed_4830"
                     /db_xref="GeneID:5318963"
     CDS             1345338..1345733
                     /locus_tag="Smed_4830"
                     /note="PFAM: response regulator receiver;
                     KEGG: sme:SMa0293 response regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver protein"
                     /protein_id="YP_001313550.1"
                     /db_xref="GI:150376954"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="GeneID:5318963"
                     /translation="MEAVTILLADDEAILLLDFESTLTDAGFLVTAVSSGAKAIELLK
                     SGAAIDGVVTDIRFCQPPDGWQVARVAREIDPNMPIVYISGHAALEWASNGVPDSIIL
                     EKPFTSAQLITAVSQLLNARPPRAPPSDA"
     misc_feature    1345392..1345712
                     /locus_tag="Smed_4830"
                     /note="FOG: CheY-like receiver [Signal transduction
                     mechanisms]; Region: CheY; COG0784"
                     /db_xref="CDD:223855"
     misc_feature    1345395..1345694
                     /locus_tag="Smed_4830"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    order(1345500..1345502,1345527..1345529,1345587..1345589,
                     1345635..1345637,1345647..1345652)
                     /locus_tag="Smed_4830"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    1345500..1345502
                     /locus_tag="Smed_4830"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    order(1345509..1345511,1345521..1345523,1345524..1345529)
                     /locus_tag="Smed_4830"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    1345647..1345655
                     /locus_tag="Smed_4830"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     gene            1345997..1346149
                     /locus_tag="Smed_4831"
                     /db_xref="GeneID:5318964"
     CDS             1345997..1346149
                     /locus_tag="Smed_4831"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313551.1"
                     /db_xref="GI:150376955"
                     /db_xref="GeneID:5318964"
                     /translation="MTYIAGLSLCRILVAQPGADFTIEAMNVARWVIHRPKVAPLSTG
                     YVRVKQ"
     gene            1346146..1346295
                     /locus_tag="Smed_4832"
                     /db_xref="GeneID:5318965"
     CDS             1346146..1346295
                     /locus_tag="Smed_4832"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313552.1"
                     /db_xref="GI:150376956"
                     /db_xref="GeneID:5318965"
                     /translation="MKRLIAVSLLGVAYLVATPLMAITVFEDGGKAYADSRDVGHKKG
                     DKQGN"
     sig_peptide     1346146..1346214
                     /locus_tag="Smed_4832"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.987) with cleavage site probability 0.791 at
                     residue 23"
     gene            complement(1346407..1346577)
                     /locus_tag="Smed_4833"
                     /db_xref="GeneID:5318966"
     CDS             complement(1346407..1346577)
                     /locus_tag="Smed_4833"
                     /note="KEGG: sme:SMb21682 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313553.1"
                     /db_xref="GI:150376957"
                     /db_xref="GeneID:5318966"
                     /translation="MSDKQGAKPHYEAGPYVNYCEHPGCTKWGGFGFAVGRGDPDWFC
                     FEHRPEWKPRQA"
     gene            complement(1346574..1347026)
                     /locus_tag="Smed_4834"
                     /db_xref="GeneID:5318967"
     CDS             complement(1346574..1347026)
                     /locus_tag="Smed_4834"
                     /note="KEGG: sme:SMb20913 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313554.1"
                     /db_xref="GI:150376958"
                     /db_xref="GeneID:5318967"
                     /translation="MRTLADEIGTAIEVDLAVMPPHQRRAYAGLDQYRRPVEVRGVQE
                     LAKGIAESFGAFAIFDVETVLRSPAIAPFVTQTLYAIPLELRRAACDRDRLKAEGARK
                     EMARIISAALLARYHFEPLKHVSASCHPNWEQAFEQQFGAGRGEGSSR"
     gene            1347147..1347974
                     /locus_tag="Smed_4835"
                     /db_xref="GeneID:5318441"
     CDS             1347147..1347974
                     /locus_tag="Smed_4835"
                     /note="PFAM: ATP dependent DNA ligase;
                     KEGG: sme:SMb20912 putative ATP-dependent DNA ligase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP dependent DNA ligase"
                     /protein_id="YP_001313555.1"
                     /db_xref="GI:150376959"
                     /db_xref="InterPro:IPR012310"
                     /db_xref="GeneID:5318441"
                     /translation="MVRASSKKPRDVAPNDPMPARIDPCLATLVDKPPIGPDWAYEVK
                     WDVCGYRLAVHIEPGRVRVLTRGGYDWTDRFPSIADDARRLAVKTAILDGEAVVLNDQ
                     GRSDFGMLQRALGRLSSAVEAGAIVFYAFDVLYLDGRDVRRLPLRERRRLLEPLVAGR
                     EGAVRLSEEVQADGDAFFSVACAHGLEGIIAKHVEKPYSSGRGEWWQKITCKRRDSFV
                     IVGFEPSTVPGHLGRLLLAARKNDDLVYLGAAARAGRTIYHASCATSSHRSLRKNRQ"
     misc_feature    1347210..1347779
                     /locus_tag="Smed_4835"
                     /note="Adenylation domain of Mycobacterium tuberculosis
                     LigD and LigC-like ATP-dependent DNA ligases; Region:
                     Adenylation_DNA_ligase_LigD_LigC; cd07906"
                     /db_xref="CDD:185715"
     misc_feature    order(1347270..1347281,1347291..1347299,1347342..1347344,
                     1347429..1347431,1347465..1347467,1347537..1347539,
                     1347705..1347707,1347714..1347716,1347720..1347722,
                     1347762..1347764,1347768..1347770)
                     /locus_tag="Smed_4835"
                     /note="active site"
                     /db_xref="CDD:185715"
     misc_feature    order(1347276..1347278,1347291..1347299,1347339..1347347,
                     1347351..1347353,1347357..1347359,1347465..1347470,
                     1347477..1347485,1347705..1347707,1347768..1347770,
                     1347774..1347776)
                     /locus_tag="Smed_4835"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:185715"
     misc_feature    1347783..>1347890
                     /locus_tag="Smed_4835"
                     /note="The Oligonucleotide/oligosaccharide binding
                     (OB)-fold domain is a DNA-binding module that is part of
                     the catalytic core unit of ATP dependent DNA ligases;
                     Region: OBF_DNA_ligase_family; cl08424"
                     /db_xref="CDD:244947"
     gene            1347971..1348129
                     /locus_tag="Smed_4836"
                     /pseudo
                     /db_xref="GeneID:5318442"
     gene            1348271..1348477
                     /locus_tag="Smed_4837"
                     /db_xref="GeneID:5318443"
     CDS             1348271..1348477
                     /locus_tag="Smed_4837"
                     /note="KEGG: sme:SMb20911 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313556.1"
                     /db_xref="GI:150376960"
                     /db_xref="GeneID:5318443"
                     /translation="MIRSVVEIIAAIFINSVGVALAAIGIESVDYGSFFQLLLVISAA
                     IVLSAMAVWAALRIFDQDYPYRLG"
     sig_peptide     1348271..1348339
                     /locus_tag="Smed_4837"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.612) with cleavage site probability 0.605 at
                     residue 23"
     gene            1348704..1349012
                     /locus_tag="Smed_4838"
                     /db_xref="GeneID:5318444"
     CDS             1348704..1349012
                     /locus_tag="Smed_4838"
                     /note="KEGG: sme:SMb20910 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313557.1"
                     /db_xref="GI:150376961"
                     /db_xref="GeneID:5318444"
                     /translation="MPEIPNEVPSKSDDDRREFLKSCGRFAIVTPPAVTMLLSTSLTS
                     NAIAKSGGGGGGGKVKGNNGWGNGPDPTNPGSSHGGGVSQGGPGAGNSQSGTKTGGAR
                     "
     gene            complement(1349164..1349460)
                     /locus_tag="Smed_4839"
                     /db_xref="GeneID:5318445"
     CDS             complement(1349164..1349460)
                     /locus_tag="Smed_4839"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313558.1"
                     /db_xref="GI:150376962"
                     /db_xref="GeneID:5318445"
                     /translation="MTDNSKTPPAKKTIEDPPEYGIASGDGTSSSWSGRGKPPEAESQ
                     ENLRGQLKWNEQRSGETGAGYQQNGQTTVAPTGTGDQAKTAGTKDWLGGPQDGA"
     gene            complement(1349450..1349620)
                     /locus_tag="Smed_4840"
                     /db_xref="GeneID:5318446"
     CDS             complement(1349450..1349620)
                     /locus_tag="Smed_4840"
                     /note="KEGG: sme:SMb21681 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313559.1"
                     /db_xref="GI:150376963"
                     /db_xref="GeneID:5318446"
                     /translation="MTFLSVTERNVRFGELIMQETITPHPSVRPDDGSTENPGSPDKN
                     PTTRNSGDRHDR"
     gene            1349715..1349870
                     /locus_tag="Smed_4841"
                     /db_xref="GeneID:5318447"
     CDS             1349715..1349870
                     /locus_tag="Smed_4841"
                     /note="KEGG: sme:SMb21680 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313560.1"
                     /db_xref="GI:150376964"
                     /db_xref="GeneID:5318447"
                     /translation="MEFVGSERSHPSFKGVRERPTKRPNITLVDALEGGYPALNTSAR
                     TRSLLTR"
     gene            1349901..1350260
                     /locus_tag="Smed_4842"
                     /db_xref="GeneID:5318448"
     CDS             1349901..1350260
                     /locus_tag="Smed_4842"
                     /note="PFAM: protein of unknown function DUF1452;
                     KEGG: sme:SMb20908 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313561.1"
                     /db_xref="GI:150376965"
                     /db_xref="InterPro:IPR010842"
                     /db_xref="GeneID:5318448"
                     /translation="MNQILFRMADFLSRPPGFYFMIVAMIVSTALVPFGLTNVITYAL
                     SVAAIVITSVVLIQGYRDTAAIHAKLDEIIVSMRETRNEVVGLEHEQPERIAAAVERL
                     EAEAAGQARAGISHLDR"
     misc_feature    1349901..>1350176
                     /locus_tag="Smed_4842"
                     /note="Predicted small integral membrane protein [Function
                     unknown]; Region: COG5478"
                     /db_xref="CDD:227765"
     gene            complement(1350850..1351344)
                     /locus_tag="Smed_4843"
                     /db_xref="GeneID:5318449"
     CDS             complement(1350850..1351344)
                     /locus_tag="Smed_4843"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313562.1"
                     /db_xref="GI:150376966"
                     /db_xref="GeneID:5318449"
                     /translation="MRSRREPGEADVLALQMIKRIDPIDVLREVMRLWMACRVQRQRI
                     RIVVDGEVRRAAERNLDADRGSTTAGEAIDHKGRADMGKSHQSVGVGRNEKLPPPIAS
                     PKNVTERFCGWKNRGHPVAIAHPWSGNELGQGIRIEPYRTDPGRRAWHGCNSLKSPTT
                     TKYQ"
     gene            1351379..1351856
                     /locus_tag="Smed_4844"
                     /pseudo
                     /db_xref="GeneID:5318450"
     gene            1351819..1353336
                     /locus_tag="Smed_4845"
                     /db_xref="GeneID:5318451"
     CDS             1351819..1353336
                     /locus_tag="Smed_4845"
                     /note="KEGG: psb:Psyr_2843 C-5 cytosine-specific DNA
                     methylase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313563.1"
                     /db_xref="GI:150376967"
                     /db_xref="GeneID:5318451"
                     /translation="MCSRRSDLSCQSDARGRTEDLNKRSTSSPVAHRGEEAVVTPYVA
                     SYYSHTNGRSERRSNLGERIATIPTENRHALIAPVLTAAQQGGSVRRVDAPHHTITAS
                     NKDQNSDIVPRLVGCGGRAGQSRPRGGDEPTGTITAKADGCVAVAFLAQNNYLEPGHD
                     AREPLSTIVGRVSTQSPIVAFIAQHNGDSRPDGSEAARPGRDSGEPLATMTQSGSQQS
                     LVSAFVARQFGNSTGHADDEPTATVMAGGDGKSQLVTPYLQAYYGTGDGQVESEPMRT
                     VTTKNRHRHVEATISAPPLTEAQAERALQVAEFMRVSLRNVPVHGLRRAYVKLKRGEY
                     ENINKAFIPLPAELAAMANAECRLIREDRIRKQERLRAIEDSVSRTLPSSHGLMDLRV
                     TQRERAIELAEKGFVRVAEGVDHLEFAHLAKSRELPAGSRHLWSPIAVRINRSRIQTK
                     LNVQPPPVSPERAAELARMLALPDVSQVTAEQMAYRGEVKADIEAAEPVDQERAA"
     gene            1353333..1353596
                     /locus_tag="Smed_4846"
                     /db_xref="GeneID:5318251"
     CDS             1353333..1353596
                     /locus_tag="Smed_4846"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313564.1"
                     /db_xref="GI:150376968"
                     /db_xref="GeneID:5318251"
                     /translation="MTIQHRTVDIEAASELWKEDLSASQIAKRFGVSRNVIVGIAFRN
                     RAFFPSRPRARNCRPHESKRAPRKDNCNARPQARYHNHPSPQI"
     misc_feature    1353360..>1353554
                     /locus_tag="Smed_4846"
                     /note="GcrA cell cycle regulator; Region: GcrA; cl11564"
                     /db_xref="CDD:245698"
     gene            1353621..1353962
                     /locus_tag="Smed_4847"
                     /db_xref="GeneID:5318252"
     CDS             1353621..1353962
                     /locus_tag="Smed_4847"
                     /note="KEGG: sme:SMb20548 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313565.1"
                     /db_xref="GI:150376969"
                     /db_xref="GeneID:5318252"
                     /translation="MPLRIEARRVRLAHQRRQPLPVLCSQDCGEILPAPSIQSICSPS
                     HYEEGKMKRSRWYPIRVAPGYKRMESIIERNCRKDGFDIFMPSFYTELRHHRTKQISR
                     SGSRSWLVMPS"
     gene            1353959..1354261
                     /locus_tag="Smed_4848"
                     /db_xref="GeneID:5318253"
     CDS             1353959..1354261
                     /locus_tag="Smed_4848"
                     /note="KEGG: sme:SMb20548 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313566.1"
                     /db_xref="GI:150376970"
                     /db_xref="GeneID:5318253"
                     /translation="MNLPRLNFEKLRGVDGVVCFLRGANYGPLEFPAPRSNPYFAKHE
                     RRQSVFYEQIHHLRGQLRKIMPKGRKARVSIVDQAERGIDSLSAQIKSGYKKSSVN"
     gene            1354437..1354664
                     /locus_tag="Smed_4849"
                     /db_xref="GeneID:5318254"
     CDS             1354437..1354664
                     /locus_tag="Smed_4849"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313567.1"
                     /db_xref="GI:150376971"
                     /db_xref="GeneID:5318254"
                     /translation="MILTVELEKAEHPGVALCFDREGLDLLIAKLETLRNRPDHMHLM
                     TPSWAGDALNEEKEGGERYEIVKSLRLVRVP"
     gene            complement(1354735..1354986)
                     /locus_tag="Smed_4850"
                     /db_xref="GeneID:5318255"
     CDS             complement(1354735..1354986)
                     /locus_tag="Smed_4850"
                     /note="TIGRFAM: acyl carrier protein;
                     PFAM: phosphopantetheine-binding;
                     KEGG: rpe:RPE_3305 acyl carrier protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="YP_001313568.1"
                     /db_xref="GI:150376972"
                     /db_xref="InterPro:IPR003231"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="GeneID:5318255"
                     /translation="MENSSANAASRVRAIIIEQLGVDPAHAVDDASIVDDLGADSLEV
                     AQIVMMIEDEFNIEISDDVAEAVITVGDAIYVVTSKTKS"
     misc_feature    complement(1354741..1354956)
                     /locus_tag="Smed_4850"
                     /note="acyl carrier protein; Provisional; Region: acpP;
                     PRK00982"
                     /db_xref="CDD:179197"
     gene            complement(1355192..1355329)
                     /locus_tag="Smed_4851"
                     /db_xref="GeneID:5318256"
     CDS             complement(1355192..1355329)
                     /locus_tag="Smed_4851"
                     /note="KEGG: sme:SMb21026 hypothetical exopeptide protein"
                     /codon_start=1
                     /transl_table=11
                     /product="exopeptide protein"
                     /protein_id="YP_001313569.1"
                     /db_xref="GI:150376973"
                     /db_xref="GeneID:5318256"
                     /translation="MDKAGVAFLVLICVLIAIVVSILWFVPENEVPPDVPEVVPQTPL
                     R"
     gene            complement(1355512..1355730)
                     /locus_tag="Smed_4852"
                     /db_xref="GeneID:5318257"
     CDS             complement(1355512..1355730)
                     /locus_tag="Smed_4852"
                     /note="KEGG: mlo:mll4695 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313570.1"
                     /db_xref="GI:150376974"
                     /db_xref="GeneID:5318257"
                     /translation="MSELEENRLLDSEFQTISSEPLIGRLNLETDLGTIDLLVNKEAA
                     EFLISVLLEFLAEGAGEDAPKFTVHTEQ"
     gene            1356087..1356344
                     /locus_tag="Smed_4853"
                     /db_xref="GeneID:5318258"
     CDS             1356087..1356344
                     /locus_tag="Smed_4853"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313571.1"
                     /db_xref="GI:150376975"
                     /db_xref="GeneID:5318258"
                     /translation="MSKPYRVVKLNTGEQDMDAVLNEWAAKGYWLNHVVRNSTYDLRA
                     DLFFTQLIAKSSHTSVHAETMIITTAIASSALCITLPRAFP"
     gene            1356768..1357058
                     /locus_tag="Smed_4854"
                     /pseudo
                     /db_xref="GeneID:5318259"
     gene            1357055..1357348
                     /locus_tag="Smed_4855"
                     /db_xref="GeneID:5318260"
     CDS             1357055..1357348
                     /locus_tag="Smed_4855"
                     /note="KEGG: mlo:mlr8001 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313572.1"
                     /db_xref="GI:150376976"
                     /db_xref="GeneID:5318260"
                     /translation="MKTYIVQALACCDSPSVVAAAVKKEYGADVSRQLVESHDPNKKA
                     GSGLARKWKTLFEETRKTFLEDSAIIAISPQAVRLRALQRMAEKAETAMRFPL"
     sig_peptide     1357055..1357114
                     /locus_tag="Smed_4855"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.771) with cleavage site probability 0.672 at
                     residue 20"
     misc_feature    1357058..1357345
                     /locus_tag="Smed_4855"
                     /note="Uncharacterized conserved protein (DUF2280);
                     Region: DUF2280; cl02353"
                     /db_xref="CDD:242999"
     gene            1357691..1357942
                     /locus_tag="Smed_4856"
                     /db_xref="GeneID:5318261"
     CDS             1357691..1357942
                     /locus_tag="Smed_4856"
                     /note="PFAM: Transglycosylase-associated protein;
                     KEGG: sme:SMa1766 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase-associated protein"
                     /protein_id="YP_001313573.1"
                     /db_xref="GI:150376977"
                     /db_xref="InterPro:IPR007341"
                     /db_xref="GeneID:5318261"
                     /translation="MGIIWTIIIGFIAGIVAKLIVPGENEPKGFILTTILGIVGAFVA
                     SYLGQALGWYNANEGAGFIGAIVGAVIVLLVWGAVARRA"
     misc_feature    1357736..>1357858
                     /locus_tag="Smed_4856"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG2261"
                     /db_xref="CDD:225170"
     gene            1357971..1358456
                     /locus_tag="Smed_4857"
                     /db_xref="GeneID:5318842"
     CDS             1357971..1358456
                     /locus_tag="Smed_4857"
                     /note="PFAM: protein of unknown function DUF937;
                     KEGG: sme:SMa1765 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313574.1"
                     /db_xref="GI:150376978"
                     /db_xref="InterPro:IPR009282"
                     /db_xref="GeneID:5318842"
                     /translation="MASSRNTMPSLAALLGLLAVAGYQNRDKLGQIFQDAKGGAQNSG
                     GILGELGKMFGGSEEGSLSKGVGELVDAFKNGGHREAADSWVSAEERSQGISPEQVES
                     SIGKDTLQDLAAKTGLDYNELLKRLSTSIPDAVDTMTPNGQLPETDEEVLGRSRGPTL
                     G"
     misc_feature    1357971..1358444
                     /locus_tag="Smed_4857"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG3753"
                     /db_xref="CDD:226276"
     sig_peptide     1357971..1358036
                     /locus_tag="Smed_4857"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.986) with cleavage site probability 0.831 at
                     residue 22"
     gene            complement(1358503..1359978)
                     /locus_tag="Smed_4858"
                     /db_xref="GeneID:5318843"
     CDS             complement(1358503..1359978)
                     /locus_tag="Smed_4858"
                     /note="PFAM: regulatory protein GntR HTH; aminotransferase
                     class I and II;
                     KEGG: sme:SMb21525 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001313575.1"
                     /db_xref="GI:150376979"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="GeneID:5318843"
                     /translation="MVGSTVSETIFFLDRTGHAGLQAQIRETIVSAVLSGRLAAGARL
                     PSSRKLAAYLNISRITVTLAYQELASQGYIEAEKRSGYRVAGKPPTTGIAIGAAHTEA
                     DTIDWSAKLCSTFIVAKQMRKPLDWRAYPYPFLYGQMDPSLFDLTAWRDCARRALGRE
                     DFELMAGDFAASDDVQLVNYICSRTLPGRGIRASPDEILVTVGAQNALWIVIQLLLRQ
                     GSHAVCENPCHPDMSASLRLSGAEVTVIDVDKEGLPPTALPDKVDAVFVTPSHHSPTG
                     ATMPLDRRAALLEAAASKDFIIVEDDYEFEMSFLAPPSPALKAFDRSGRVFYIGSFSK
                     SLFPGLRLGYLVAPAAVIREARALRALMLRHPPGHLQRTAAYFLALGHYDAVLHRMRE
                     EYHRRHIIMAAALRDAGLRIAGSAAFGGTSFWIEGPDDLDADLLMNALRLEGVLIESG
                     SPFFPKDDGPCRFFRMGYSSIARSRIADGVALTAARIADRA"
     misc_feature    complement(1358506..1359930)
                     /locus_tag="Smed_4858"
                     /note="Transcriptional regulators containing a DNA-binding
                     HTH domain and an aminotransferase domain (MocR family)
                     and their eukaryotic orthologs [Transcription / Amino acid
                     transport and metabolism]; Region: ARO8; COG1167"
                     /db_xref="CDD:224089"
     misc_feature    complement(1359724..1359918)
                     /locus_tag="Smed_4858"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    complement(order(1359733..1359744,1359748..1359753,
                     1359781..1359783,1359790..1359795,1359799..1359813,
                     1359835..1359840,1359844..1359846,1359913..1359915))
                     /locus_tag="Smed_4858"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     misc_feature    complement(1358536..1359438)
                     /locus_tag="Smed_4858"
                     /note="Aspartate aminotransferase family. This family
                     belongs to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). Pyridoxal phosphate
                     combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine...; Region: AAT_like;
                     cd00609"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(1358956..1358958,1358977..1358982,
                     1358986..1358988,1359067..1359069,1359160..1359162,
                     1359292..1359294,1359364..1359372))
                     /locus_tag="Smed_4858"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99734"
     misc_feature    complement(order(1358860..1358862,1358869..1358871,
                     1358956..1358964,1359088..1359090,1359262..1359264,
                     1359361..1359363))
                     /locus_tag="Smed_4858"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99734"
     misc_feature    complement(1358977..1358979)
                     /locus_tag="Smed_4858"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
     gene            1360143..1361162
                     /locus_tag="Smed_4859"
                     /db_xref="GeneID:5318844"
     CDS             1360143..1361162
                     /locus_tag="Smed_4859"
                     /note="TIGRFAM: taurine ABC transporter, periplasmic
                     binding protein;
                     PFAM: Substrate-binding region of ABC-type glycine betaine
                     transport system;
                     SMART: extracellular solute-binding protein family 3;
                     KEGG: sme:SMb21526 putative taurine uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter periplasmic binding
                     protein"
                     /protein_id="YP_001313576.1"
                     /db_xref="GI:150376980"
                     /db_xref="InterPro:IPR001638"
                     /db_xref="InterPro:IPR007210"
                     /db_xref="InterPro:IPR010068"
                     /db_xref="GeneID:5318844"
                     /translation="MIHYRKFKLISGALAIATGLLAGFAARAETSVVVGYQQIVGPFI
                     SAIADGRFDAAAKEAGYSIDWRQFSSGGDISTALASGNVPIGVIGSTGTTAAATRGVE
                     LELFWILDNIGKSEALVAREGSGIAKPEDLIGKNVGVPFVSTSHFHLLVGLGEVWKID
                     PREVNILNMKPPQIVAAWQRGDIDAAYVWPPALSELLKTGKVISDSEAVGAASVPTFD
                     GLVVDKKWAEENPDFMAAFTRVLAESYADFKANGSGWTADSPEVQGMVKLIGGDAEGI
                     VQALNLLSFPTAEEQVSDRWLGGGAVRALEASARFLVEQKQIDNALDDYAPFVNSAYA
                     KEVSK"
     sig_peptide     1360143..1360229
                     /locus_tag="Smed_4859"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.994 at
                     residue 29"
     misc_feature    1360236..1361147
                     /locus_tag="Smed_4859"
                     /note="taurine ABC transporter, periplasmic binding
                     protein; Region: taurine_ABC_bnd; TIGR01729"
                     /db_xref="CDD:130790"
     misc_feature    1360236..1360883
                     /locus_tag="Smed_4859"
                     /note="Bacterial periplasmic transport systems use
                     membrane-bound complexes and substrate-bound,
                     membrane-associated, periplasmic binding proteins (PBPs)
                     to transport a wide variety of  substrates, such as, amino
                     acids, peptides, sugars, vitamins and inorganic...;
                     Region: PBPb; cd00134"
                     /db_xref="CDD:238078"
     misc_feature    order(1360260..1360262,1360350..1360352,1360437..1360439,
                     1360572..1360574,1360707..1360709)
                     /locus_tag="Smed_4859"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238078"
     misc_feature    order(1360656..1360658,1360668..1360670,1360686..1360688)
                     /locus_tag="Smed_4859"
                     /note="membrane-bound complex binding site; other site"
                     /db_xref="CDD:238078"
     misc_feature    order(1360770..1360784,1360797..1360799)
                     /locus_tag="Smed_4859"
                     /note="hinge residues; other site"
                     /db_xref="CDD:238078"
     gene            1361253..1362065
                     /locus_tag="Smed_4860"
                     /db_xref="GeneID:5318845"
     CDS             1361253..1362065
                     /locus_tag="Smed_4860"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21527 putative taurin uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313577.1"
                     /db_xref="GI:150376981"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318845"
                     /translation="METLNVSNVNLTYPGLYSDQAVIALKGVNLEIKSGDFVVALGAS
                     GCGKTTLLNLMAGFMAPSAGEITLGERRITGPGADRGVVFQKHALLPWLNVIDNTEFG
                     LKLRGVDKATRREVATRNLALVGLQDFHRHMIYHLSGGMQQRVGIARALTCDPAMLLM
                     DEPMAALDALTRETIQELLLKVWQLTNKMFFFITHSVEEALFLGSRLIVMSPRPGRIT
                     HTYELDFNKRFLENGHARAIKSSRDFIDMREQILGIIYGDERQSGNPELLHA"
     misc_feature    1361253..1362041
                     /locus_tag="Smed_4860"
                     /note="ABC-type taurine transport system, ATPase component
                     [Inorganic ion transport and metabolism]; Region: TauB;
                     COG4525"
                     /db_xref="CDD:226905"
     misc_feature    1361262..1361927
                     /locus_tag="Smed_4860"
                     /note="ATP-binding cassette domain of the nitrate and
                     sulfonate transporters; Region:
                     ABC_NrtD_SsuB_transporters; cd03293"
                     /db_xref="CDD:213260"
     misc_feature    1361376..1361399
                     /locus_tag="Smed_4860"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213260"
     misc_feature    order(1361385..1361390,1361394..1361402,1361505..1361507,
                     1361733..1361738,1361835..1361837)
                     /locus_tag="Smed_4860"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213260"
     misc_feature    1361496..1361507
                     /locus_tag="Smed_4860"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213260"
     misc_feature    1361661..1361690
                     /locus_tag="Smed_4860"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213260"
     misc_feature    1361721..1361738
                     /locus_tag="Smed_4860"
                     /note="Walker B; other site"
                     /db_xref="CDD:213260"
     misc_feature    1361745..1361756
                     /locus_tag="Smed_4860"
                     /note="D-loop; other site"
                     /db_xref="CDD:213260"
     misc_feature    1361823..1361843
                     /locus_tag="Smed_4860"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213260"
     gene            1362058..1362885
                     /locus_tag="Smed_4861"
                     /db_xref="GeneID:5318846"
     CDS             1362058..1362885
                     /locus_tag="Smed_4861"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21528 putative taurine uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313578.1"
                     /db_xref="GI:150376982"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318846"
                     /translation="MLEGVVKSKPVRPGRIYGAPGDGMSGHISLLTALVLIAFWLLVT
                     EMGWIKPLFLPSPLAVWDKFVIALTEGVSNSTLAQHTLASLGRVFGAFLLALVTAVPV
                     GILMGVNRVVRGLFDPIIEFYRPLPPLAYLPLIIIWLGIGEFPKVFLIYLAIFAPMAI
                     AARAGVRSVSTEQIHAAYAMGATRAQVIGHVIMKAALPEIFTGMRIGIGVGWTTLVAA
                     EMVAAHRGLGFMVLNAAEYLASDTVIMGIVVIGVFAFAFDLMIRYLEKTLIPWKGKV"
     misc_feature    1362133..1362882
                     /locus_tag="Smed_4861"
                     /note="ABC-type nitrate/sulfonate/bicarbonate transport
                     system, permease component [Inorganic ion transport and
                     metabolism]; Region: TauC; COG0600"
                     /db_xref="CDD:223673"
     misc_feature    1362307..1362816
                     /locus_tag="Smed_4861"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1362346..1362351,1362358..1362363,1362376..1362378,
                     1362403..1362414,1362418..1362447,1362454..1362459,
                     1362463..1362465,1362511..1362516,1362520..1362522,
                     1362526..1362528,1362535..1362540,1362544..1362546,
                     1362556..1362561,1362568..1362570,1362619..1362621,
                     1362661..1362666,1362673..1362675,1362694..1362705,
                     1362712..1362717,1362754..1362759,1362787..1362792,
                     1362799..1362804,1362808..1362813)
                     /locus_tag="Smed_4861"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1362421..1362465,1362694..1362711)
                     /locus_tag="Smed_4861"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1362463..1362465,1362496..1362498,1362712..1362714,
                     1362748..1362750,1362757..1362759,1362787..1362789)
                     /locus_tag="Smed_4861"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1362571..1362609,1362625..1362630,1362640..1362642)
                     /locus_tag="Smed_4861"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1363005..1363391
                     /locus_tag="Smed_4862"
                     /db_xref="GeneID:5318847"
     CDS             1363005..1363391
                     /locus_tag="Smed_4862"
                     /note="PFAM: protein of unknown function DUF1486;
                     KEGG: sme:SMb21670 taurine dehydrogenase small subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313579.1"
                     /db_xref="GI:150376983"
                     /db_xref="InterPro:IPR009959"
                     /db_xref="GeneID:5318847"
                     /translation="MTAEDLAELFDAFNRHDIDSVMAFFAADCVFNAVAGPEACGKRI
                     VGAEAIADAFSGVWAAMPDAHWDHHSHFVHGDRGVSEWTFSGTNADGTRIVAEGCDLF
                     TLRDGKIVRKQAFRKNRPLIEPQPRY"
     misc_feature    1363020..1363337
                     /locus_tag="Smed_4862"
                     /note="SnoaL-like domain; Region: SnoaL_2; pfam12680"
                     /db_xref="CDD:221707"
     gene            1363416..1364816
                     /locus_tag="Smed_4863"
                     /db_xref="GeneID:5318848"
     CDS             1363416..1364816
                     /locus_tag="Smed_4863"
                     /note="PFAM: FAD dependent oxidoreductase;
                     KEGG: sme:SMb21529 taurine dehydrogenase large subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD dependent oxidoreductase"
                     /protein_id="YP_001313580.1"
                     /db_xref="GI:150376984"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="GeneID:5318848"
                     /translation="MEHQLARPIASRKPFDPTYDPIRAPNPGEGKDYAPTYWIGTAGK
                     PPSDDGPVTCDMDVDVAIVGSGYTGLSCAIHLAREHGIKATVLEANGVAWGCSTRNGG
                     QAQISAGRLKRSQWIERWGVDIAKKLHVEISEAFDLFRDLIRSPEIDCDAQDGGHLYI
                     AHRDKVMPALESESRLLNEVFGYRSRIVGREEVHRDFVRDEEAKGAMYEPDGMGIHAA
                     KLAFGYLNLARKLGARVHTASPVLTCDWKNGAYHLSTPGGTVRARAVCIATAGYTSPD
                     LHSLTRHRLMPILSNSIVTRPLNEEERSELNFKTRIPLTDTRTLRHYYRIMPDGRVQI
                     GSRSAITGRDAVNPKHLGRLLEGLYRKFPVLKGITIDYSWWGWVDVSHDMMPRIFRPD
                     PKQPLFYAMGYGGNGVMYSAQAGRRMAQMVAGQGGALDLPIFTSPLPSHGLLTPFRRL
                     GQWGMYRWYYLKDEIL"
     misc_feature    1363524..1364768
                     /locus_tag="Smed_4863"
                     /note="putative aminophosphonate oxidoreductase; Region:
                     Phn_aa_oxid; TIGR03329"
                     /db_xref="CDD:132372"
     misc_feature    1363578..1364717
                     /locus_tag="Smed_4863"
                     /note="Glycine/D-amino acid oxidases (deaminating) [Amino
                     acid transport and metabolism]; Region: DadA; COG0665"
                     /db_xref="CDD:223737"
     gene            complement(1364828..1365592)
                     /locus_tag="Smed_4864"
                     /db_xref="GeneID:5318849"
     CDS             complement(1364828..1365592)
                     /locus_tag="Smed_4864"
                     /note="PFAM: regulatory protein IclR; Transcriptional
                     regulator IclR;
                     KEGG: reh:H16_A2746 transcriptional regulator,
                     IclR-family"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator IclR"
                     /protein_id="YP_001313581.1"
                     /db_xref="GI:150376985"
                     /db_xref="InterPro:IPR005471"
                     /db_xref="InterPro:IPR011571"
                     /db_xref="InterPro:IPR014757"
                     /db_xref="GeneID:5318849"
                     /translation="MRMDDKIETPNSAVTRSLSLIEVVGLSEKPVTLNDLAERIDMPR
                     ATLHRLCQRLVEEGFLFREPDRRHYSVGPRLFKMGLTIVGSGVGTQRHAILKQVVDVT
                     RETCNFVTRSGCDAIYLARVESDWPLRVHLEPGSRVPLHCTASGKLLLAHMDVQQRQK
                     LLASLTFERFTPATIMSADALESEFAEILRDGYSTDREEFMIGLIAIAVPVFDRNGRV
                     VASLACHAPKARMTLDDSKRYVPVLQSAARKLAQTF"
     misc_feature    complement(1364837..1365559)
                     /locus_tag="Smed_4864"
                     /note="Transcriptional regulator [Transcription]; Region:
                     IclR; COG1414"
                     /db_xref="CDD:224332"
     misc_feature    complement(1365338..1365517)
                     /locus_tag="Smed_4864"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cd00090"
                     /db_xref="CDD:238042"
     misc_feature    complement(order(1365359..1365361,1365488..1365490,
                     1365497..1365499))
                     /locus_tag="Smed_4864"
                     /note="putative Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    complement(order(1365380..1365388,1365401..1365409,
                     1365425..1365430,1365434..1365439,1365446..1365451,
                     1365455..1365466,1365491..1365499))
                     /locus_tag="Smed_4864"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238042"
     misc_feature    complement(1364843..1365214)
                     /locus_tag="Smed_4864"
                     /note="Bacterial transcriptional regulator; Region: IclR;
                     pfam01614"
                     /db_xref="CDD:201890"
     gene            1365728..1367347
                     /locus_tag="Smed_4865"
                     /db_xref="GeneID:5318850"
     CDS             1365728..1367347
                     /locus_tag="Smed_4865"
                     /note="PFAM: glucose-methanol-choline oxidoreductase; FAD
                     dependent oxidoreductase; GMC oxidoreductase;
                     KEGG: reh:H16_B1851 glucose-methanol-choline
                     oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-methanol-choline oxidoreductase"
                     /protein_id="YP_001313582.1"
                     /db_xref="GI:150376986"
                     /db_xref="InterPro:IPR000172"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR007867"
                     /db_xref="GeneID:5318850"
                     /translation="MREEPNVNEAQFDYIVVGAGSSGCTVAARLSEDGRFRVALVEAG
                     PKDTSPWIHLPLGYGKTMWDERINWKLYTEPDPNMNGRRIYWPRGKVLGGCSAINGLI
                     AIRGQAEDYDDWARYGGDQWNYRNVLPHFRKSESFAGAANPEFHGKHGPICVAPIRHR
                     HPLIDAFIGSANQLGIPCNDDFNGPSQEGVGYYSLTTRNGMRSSAAVGYLRPAKRRSN
                     LTIVTEALVTKVRFEGRRAQGIDYTTNGRKMSMNARRGVILSAGAVHTPHLMMLSGIG
                     PAAHLKAHGIDVVADMPGVGANLRDHLQLRLIYRCNRPITTNDELNSLTGKVKIGLQW
                     LLTRTGPLAVGINQGGLFARVMPDATRPDVQFHVATLSADMAGGKVHPFSGFTMSVCQ
                     LRPESHGTIRLACADPTTPPLIHANYLDAELDRQIAIGGIRLARRIARTGPLSQLVTR
                     EELPGESVDSKEGILDFARQNGATIFHPTSTCRMGQDDDADAVVRPDLKVRGFDGLWI
                     ADCSVMPTIVSGNTNLPAIMIGEKLSSSILN"
     misc_feature    1365758..1367341
                     /locus_tag="Smed_4865"
                     /note="choline dehydrogenase; Validated; Region: PRK02106"
                     /db_xref="CDD:235000"
     misc_feature    1365773..>1365862
                     /locus_tag="Smed_4865"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; cl17500"
                     /db_xref="CDD:248054"
     misc_feature    1366910..1367326
                     /locus_tag="Smed_4865"
                     /note="GMC oxidoreductase; Region: GMC_oxred_C; pfam05199"
                     /db_xref="CDD:218493"
     gene            1367370..1368707
                     /locus_tag="Smed_4866"
                     /db_xref="GeneID:5318851"
     CDS             1367370..1368707
                     /locus_tag="Smed_4866"
                     /note="PFAM: General substrate transporter; major
                     facilitator superfamily MFS_1;
                     KEGG: pde:Pden_4279 major facilitator superfamily MFS_1"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001313583.1"
                     /db_xref="GI:150376987"
                     /db_xref="InterPro:IPR005828"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5318851"
                     /translation="MLNTAGSTRESEVRRVVFASLIGATIEWYDFFLYGVIAGIVFNQ
                     LYFPSHDPLVSMVLAYATFAVGFVARPLGGIVFGHFGDKLGRKQMLVLTILIMGVATV
                     LIGVLPTYEQIGVAAPILLLILRIAQGIGIGGEWGGAVLMAYEFAPEDKRGYYASIPQ
                     IGLAIGLCLSSGVVALLSLLPEAAFMSWGWRTAFIGSVVLIVVGLYIRLKVAETPDFA
                     SVKEERQELKIPFVELIRTYPRNILLGMGARYIDGVFFNVFAVFSIVYLSKHVQVDRT
                     TALWLVCLSALVMVVTIPLFGKLSDRWGRPKTYAIGSLLLALVTFPAFMLMGSGSLPL
                     IALALIVPFGIIYAMCYGPEAALFSDLFDVKVRYTGISFVYQFSGIFASGITPIIATF
                     LISYGDGSPWLLAAYVVFAALVSMVSAMLIRPVSQMRTTLPHKPLRPSPVHTS"
     misc_feature    1367418..1368575
                     /locus_tag="Smed_4866"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    1367436..1368560
                     /locus_tag="Smed_4866"
                     /note="metabolite-proton symporter; Region: 2A0106;
                     TIGR00883"
                     /db_xref="CDD:233168"
     misc_feature    order(1367460..1367462,1367469..1367477,1367481..1367486,
                     1367556..1367558,1367565..1367570,1367577..1367579,
                     1367589..1367594,1367598..1367603,1367763..1367768,
                     1367775..1367780,1367787..1367792,1367799..1367801,
                     1367835..1367840,1367847..1367852,1367868..1367870,
                     1368126..1368128,1368135..1368140,1368147..1368152,
                     1368159..1368161,1368201..1368203,1368213..1368215,
                     1368225..1368227,1368234..1368236,1368246..1368248,
                     1368399..1368401,1368408..1368413,1368420..1368422,
                     1368432..1368437,1368444..1368446,1368477..1368482,
                     1368489..1368494,1368501..1368506,1368513..1368515)
                     /locus_tag="Smed_4866"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            1368718..1370493
                     /locus_tag="Smed_4867"
                     /db_xref="GeneID:5318852"
     CDS             1368718..1370493
                     /locus_tag="Smed_4867"
                     /note="catalyzes the formation of acetyl phosphate and
                     sulfite from 2-sulfoacetaldehyde; is active when grown on
                     taurine as a sole carbon source"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoacetaldehyde acetyltransferase"
                     /protein_id="YP_001313584.1"
                     /db_xref="GI:150376988"
                     /db_xref="InterPro:IPR000399"
                     /db_xref="InterPro:IPR011766"
                     /db_xref="InterPro:IPR012000"
                     /db_xref="InterPro:IPR012001"
                     /db_xref="GeneID:5318852"
                     /translation="MKMTTEEAFVKVLQMHGIEHAFGIIGSAMMPVSDLFPKAGIKFW
                     DCAHETNAGMMADGFSRATGTMSMAIGQNGPGVTGFITAMKTAYWNHTPLLMVTPQAA
                     NKTIGQGGFQEVDQMAMFEEMVCYQEEVRDPSRIPEVLNRVIEKAWRGCAPAQINIPR
                     DFWTHVIDVDLPRIVRFERPAGGPAAIAQAARLLSEAKFPVILNGAGVVIGNAIQESM
                     ALAERLNAPVCCGYQHNDAFPGSHRLSVGPLGYNGSKAAMELISKADVVLALGTRLNP
                     FSTLPGYGIDYWPKNASIIQVDINPDRIGLTKKVTVGICGDAKQVAQQILQQLAPVAG
                     EASREERKALVHQTRSAWLQQLSSMDHEDDDPGTEWNVGARQREPDRMSPRQVWRAIQ
                     AVLPKEAIISTDIGNNCAIGNAYPSFEQGRKYLAPGMFGPCGYGFPSIVGAKIGCPDV
                     PVVGFAGDGAFGISMNEMTSIGREGWPAITMVIFRNYQWGAEKRNTTLWYDNNFVGTE
                     LNPNLSYAKVADGSGLKGITVDTPAALKEALSKAIEDQARGITTFVEVILNQELGEPF
                     RRDAMKKPVAVAGIDRADMQPQSRR"
     misc_feature    1368718..1370472
                     /locus_tag="Smed_4867"
                     /note="sulfoacetaldehyde acetyltransferase; Validated;
                     Region: PRK07525"
                     /db_xref="CDD:236042"
     misc_feature    1368736..1369197
                     /locus_tag="Smed_4867"
                     /note="Pyrimidine (PYR) binding domain of POX and related
                     proteins; Region: TPP_PYR_POX_like; cd07035"
                     /db_xref="CDD:132918"
     misc_feature    order(1368775..1368777,1368790..1368795,1368805..1368807,
                     1368817..1368819,1368841..1368861,1368868..1368870,
                     1368877..1368882,1368889..1368894,1368898..1368906,
                     1368940..1368942,1368961..1368963,1368973..1368975,
                     1368982..1368987)
                     /locus_tag="Smed_4867"
                     /note="PYR/PP interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    order(1368790..1368798,1368805..1368807,1368817..1368819,
                     1368844..1368846,1368850..1368861,1368865..1368867,
                     1368940..1368942,1368949..1368954,1368958..1368963,
                     1368970..1368972,1369072..1369074,1369081..1369083)
                     /locus_tag="Smed_4867"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    order(1368790..1368792,1368862..1368864,1368940..1368942,
                     1368952..1368954)
                     /locus_tag="Smed_4867"
                     /note="TPP binding site [chemical binding]; other site"
                     /db_xref="CDD:132918"
     misc_feature    1369291..1369692
                     /locus_tag="Smed_4867"
                     /note="Thiamine pyrophosphate enzyme, central domain;
                     Region: TPP_enzyme_M; pfam00205"
                     /db_xref="CDD:215786"
     misc_feature    1369852..1370445
                     /locus_tag="Smed_4867"
                     /note="Thiamine pyrophosphate (TPP) family, Xsc-like
                     subfamily, TPP-binding module; composed of proteins
                     similar to Alcaligenes defragrans sulfoacetaldehyde
                     acetyltransferase (Xsc). Xsc plays a key role in the
                     degradation of taurine, catalyzing the...; Region:
                     TPP_Xsc_like; cd02013"
                     /db_xref="CDD:238971"
     misc_feature    order(1370014..1370016,1370086..1370097,1370173..1370175,
                     1370179..1370181)
                     /locus_tag="Smed_4867"
                     /note="TPP-binding site; other site"
                     /db_xref="CDD:238971"
     gene            1370553..1371590
                     /locus_tag="Smed_4868"
                     /db_xref="GeneID:5318915"
     CDS             1370553..1371590
                     /locus_tag="Smed_4868"
                     /note="PFAM: conserved hypothetical protein 698;
                     KEGG: sme:SMb21531 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313585.1"
                     /db_xref="GI:150376989"
                     /db_xref="InterPro:IPR004630"
                     /db_xref="GeneID:5318915"
                     /translation="MDAISRTERPKQSPKAVLSTYGPGLLVTAAVAMAAQFLSEHYGA
                     PAMLMALLLGIAFHFLAEEGRCVAGIELSAKLVLRIGVALLGMRISVDLLIGLGAGTI
                     LLLVSAIAATILFGLVAARLLGRGWRLALLTSGAVAICGASAAMAIASVLPRNEFSER
                     NLIFTVLSVTVLSTLAMIGYPIVAEYLGLDGQATGIFLGGTIHDVAQVVGAGFSVSPE
                     AGETATLVKLIRVTMLAPVVLIFSVALRGVPQEGTSIGRRAPLVPGFVLAFLILAGFN
                     SAGLVPVLVSEIGMEISRWALLAGIVAVGMKTSLRRVLEVGGDAVALVVAETLFIAVF
                     ILVGMNYLGHS"
     sig_peptide     1370553..1370657
                     /locus_tag="Smed_4868"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.984) with cleavage site probability 0.980 at
                     residue 35"
     misc_feature    1370613..1371584
                     /locus_tag="Smed_4868"
                     /note="Predicted membrane protein [Function unknown];
                     Region: COG2855"
                     /db_xref="CDD:225411"
     gene            1371590..1372624
                     /locus_tag="Smed_4869"
                     /db_xref="GeneID:5318916"
     CDS             1371590..1372624
                     /locus_tag="Smed_4869"
                     /EC_number="2.3.1.8"
                     /note="TIGRFAM: phosphate acetyltransferase;
                     PFAM: phosphate acetyl/butaryl transferase;
                     KEGG: sme:SMb21532 putative phosphate acetyltransferase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="YP_001313586.1"
                     /db_xref="GI:150376990"
                     /db_xref="InterPro:IPR002505"
                     /db_xref="InterPro:IPR004614"
                     /db_xref="GeneID:5318916"
                     /translation="MKPLDRIIETARKAPRHIVLSEGEDPRIVAGAVRARRECLAEIT
                     LVGNREVVMHRLAALDANPREFRVEDPSSSSLTDGFAASFLDLRRSKGVDEAAARVAV
                     LTPLNFAAMMVREGLADGTVGGAVATTADTVRAALQVIGRAPGVGLVSSFFLMMLCEP
                     HHARKGAFVFADCGLVVDPDAGGLADIALMSAKSYEQLAGERAKVAMLSFSTGGSAAH
                     ERVSKVVEATRMARCAEPDLVIDGELQFDSAFVEAVSLTKAPQSALRGEANVFVFPNL
                     DAANIGYKIAQRIGGATAIGPILQGLARPANDLSRGCSADDVFHMIAVTVVQGREDNS
                     TVSERRQNVT"
     misc_feature    1371590..1372573
                     /locus_tag="Smed_4869"
                     /note="Phosphate acetyl/butaryl transferase; Region:
                     PTA_PTB; cl17212"
                     /db_xref="CDD:247766"
     gene            1372624..1373490
                     /locus_tag="Smed_4870"
                     /db_xref="GeneID:5318917"
     CDS             1372624..1373490
                     /locus_tag="Smed_4870"
                     /note="PFAM: regulatory protein GntR HTH; regulatory
                     protein DeoR; Helix-turn-helix type 11 domain protein;
                     regulatory protein DeoR;
                     KEGG: sme:SMb21533 putative transcriptional regulator,
                     GntR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="YP_001313587.1"
                     /db_xref="GI:150376991"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR001034"
                     /db_xref="InterPro:IPR013196"
                     /db_xref="InterPro:IPR014036"
                     /db_xref="GeneID:5318917"
                     /translation="MQKVYYAAFAIFATSLAACREYCNIVGMSRSANSRALAPRRHEE
                     ILRRLAAEGSVSIAELSAHFDVSRETIRRDMKLLADRGQLDVVHGGATLFEPIEPALV
                     HRSEENATAKAAIGLKAAELVKDGMVVFLDSGTTTLAVAHALDGLRDLTVCTTGLAIA
                     LHMCRQPRARVHMLGGEIDPAEEAAVGLDALEAIGRFRVDIAFLGGGGLSPDGEVTDF
                     TRNGAEQRSRMIAMAGKAYFVLDSSKFGRLTPLRIPGFHQAAGVIVDAPPAPTISEAL
                     ERKGPRVIVATR"
     misc_feature    1372732..1373481
                     /locus_tag="Smed_4870"
                     /note="Transcriptional regulators of sugar metabolism
                     [Transcription / Carbohydrate transport and metabolism];
                     Region: GlpR; COG1349"
                     /db_xref="CDD:224268"
     misc_feature    1372744..1372902
                     /locus_tag="Smed_4870"
                     /note="helix_turn_helix, Deoxyribose operon repressor;
                     Region: HTH_DEOR; smart00420"
                     /db_xref="CDD:197714"
     misc_feature    1372984..1373424
                     /locus_tag="Smed_4870"
                     /note="DeoR C terminal sensor domain; Region: DeoRC;
                     pfam00455"
                     /db_xref="CDD:201239"
     gene            1373571..1376048
                     /locus_tag="Smed_4871"
                     /db_xref="GeneID:5318918"
     CDS             1373571..1376048
                     /locus_tag="Smed_4871"
                     /note="PFAM: FAD dependent oxidoreductase; glycine
                     cleavage T protein (aminomethyl transferase); Glycine
                     cleavage T-protein barrel;
                     KEGG: sme:SMb21534 putative dehydrogenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD dependent oxidoreductase"
                     /protein_id="YP_001313588.1"
                     /db_xref="GI:150376992"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR006222"
                     /db_xref="InterPro:IPR013977"
                     /db_xref="GeneID:5318918"
                     /translation="MPQEFPTQARVVIIGGGIIGCSVAYHLTQLGWTDVVLLEQGQLS
                     GGTTWHAAGLVGQLRSHANMTGLIRYSTQLYSELEAETGLATGWKNCGSLAVARTADR
                     MTVLKRTAASARAQGVAVEVISPREAADLWPVMAVEDLVGAVWLPGDGKANPTDLTQS
                     LAKGARNRGARIIERVRVTGITAKDGTVRGVETDRGSIAAEIVVNCAGQWARKVGLMC
                     GVTVPLHSAEHMYIVTGKIEGVHPDLPVLRDPDGYIYFKEEVGGLVMGGFEPEAKPWG
                     MNGIPDDFEFALLEDDWDQFEVLMQNALIRVPQLETAEVRKFYNGPESFTPDNNFILG
                     EAPELRNFYVGAGFNSMGIASAGGAGRALAEWIVNGAPTIDLWPVDIRRFARFNNNPR
                     WLHDRVKETLGLHYAMPWPNRELHTARPFRRSPLYDRLASRGACFGSKMGWERANWFA
                     EAGQEAETDYAFGRQNWHEAVKREMRATRQAAGIFDQTSFAKLLVQGRDAAKALNRIC
                     AADIDVEIGRSIYTGMLNARGGYESDLTVMRLAPDRFLIVTGSAQAVHDADWIRRNIP
                     VDAHVTLTDVTSSYAVLALMGPNARDILGRITSADLSNAGFPFSTICEIDIGYATAFA
                     NRMTYVGELGWELIVPSEFAVGVYEALHEAGRDLGLIDCGYYALEALRIEKGFRAWSR
                     ELTPDINPYEAGLAFAVSLDKPGGFIGREALVRARQAGPPVKRIVQFTLDDAEPMLWG
                     GELILRDGKPVGEVRSAAYGHTLGRSVALGLIEHDEGVGREFIGNGHFEIDLAGDRQS
                     ATAHLKCPYDPKSERVRVDADEPRAAA"
     misc_feature    1373586..1374731
                     /locus_tag="Smed_4871"
                     /note="Glycine/D-amino acid oxidases (deaminating) [Amino
                     acid transport and metabolism]; Region: DadA; COG0665"
                     /db_xref="CDD:223737"
     misc_feature    <1373832..>1374311
                     /locus_tag="Smed_4871"
                     /note="hydroxyglutarate oxidase; Provisional; Region:
                     PRK11728"
                     /db_xref="CDD:183292"
     misc_feature    1374819..1376018
                     /locus_tag="Smed_4871"
                     /note="Glycine cleavage system T protein
                     (aminomethyltransferase) [Amino acid transport and
                     metabolism]; Region: GcvT; COG0404"
                     /db_xref="CDD:223481"
     misc_feature    1374999..1375550
                     /locus_tag="Smed_4871"
                     /note="Sarcosine oxidase, gamma subunit family; Region:
                     SoxG; cl01893"
                     /db_xref="CDD:242769"
     misc_feature    1375569..1375763
                     /locus_tag="Smed_4871"
                     /note="folate-binding protein YgfZ; Region:
                     ygfZ_signature; TIGR03317"
                     /db_xref="CDD:234167"
     misc_feature    1375683..>1375895
                     /locus_tag="Smed_4871"
                     /note="Glycine cleavage T-protein C-terminal barrel
                     domain; Region: GCV_T_C; pfam08669"
                     /db_xref="CDD:219963"
     gene            complement(1376052..1376939)
                     /locus_tag="Smed_4872"
                     /db_xref="GeneID:5318919"
     CDS             complement(1376052..1376939)
                     /locus_tag="Smed_4872"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb21535 putative transcriptional regulator,
                     LysR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001313589.1"
                     /db_xref="GI:150376993"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318919"
                     /translation="MIGPHPMRYVQLRAFHNVAVCGGFSRAAEALFLTQPAVSDQVRK
                     LEEEYDVLLFNRNKKQVTLTQAGHQLLEITRRMFDTEQQALDLLSESRALRAGTLRIV
                     ADAAHHLLHILAAFRKKYPTVQISLRAGNTETVITSLYSYEADIGVLGEIPESREFDI
                     VKLNSTPIIAFASTEHPIACRSNVSLEELAGQPLVMRERGSKTRQKLEDFAAAAGVAL
                     KPAIEAEGREAVREIVAAGAGVGFVSAAEFGRDGRLAPIEIIGAEMLMDEALICLKER
                     SGGKLVRAFFEIARSLAEK"
     misc_feature    complement(1376073..1376909)
                     /locus_tag="Smed_4872"
                     /note="aminoethylphosphonate catabolism associated LysR
                     family transcriptional regulator; Region: phn_lysR;
                     TIGR03339"
                     /db_xref="CDD:132382"
     misc_feature    complement(1376736..1376909)
                     /locus_tag="Smed_4872"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    complement(1376073..1376594)
                     /locus_tag="Smed_4872"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cd05466"
                     /db_xref="CDD:176102"
     misc_feature    complement(order(1376238..1376240,1376241..1376246,
                     1376262..1376279,1376553..1376573,1376577..1376579,
                     1376589..1376591))
                     /locus_tag="Smed_4872"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            1377033..1378706
                     /locus_tag="Smed_4873"
                     /db_xref="GeneID:5318920"
     CDS             1377033..1378706
                     /locus_tag="Smed_4873"
                     /note="PFAM: Na+cotransporter; PhoU family protein;
                     KEGG: sme:SMb21536 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+cotransporter"
                     /protein_id="YP_001313590.1"
                     /db_xref="GI:150376994"
                     /db_xref="InterPro:IPR003841"
                     /db_xref="InterPro:IPR008170"
                     /db_xref="GeneID:5318920"
                     /translation="MTVITLSLHLAGATVLLLYAVHLVRSGVENAYGPSLKRVLAKGG
                     ERRVYAAASGTALAVLLQSSTAVAMLASGLAASGYLTLNTSLAVLLGADFGSALVVRV
                     LSFDLGWMSPLLLAAGGLCYLKGRTDKFHEIGRMLLGIAFVLMSLKLIGEATVPLKRS
                     EVLPAIVGYLAEDQVMSFVAAALFTWIVHSSVAVLILILGFAAQGLLPIEAGLPLILG
                     ANLGSGMIAIWLTRGFPAEARRVAAGNFLFRALGAAITLPVCGVLAGRIQALGTTPAE
                     QLVHFHLVFNACLVLICLPLSQLAAGAVSSLVKSDPGRFDDNDPLAGRISALDEGLLD
                     SPDAALAAATREVLFMGEMVERMLCPVMELLEHPNRRKLEEIRRLDEHVNRAHRGIKL
                     YLAAINRGVLDEPQSRKGVELIDIAINLEHAGDIVSKTLVEIVRDKLENGNSFSNEGW
                     TELKMLHASVRDNMRLAFNLLVSGDPAMARRLVREKERVRGLVRESRERHLARLRAGR
                     PESVESSNMHLEIARALKEVNSLLATLAYPILKQRGDLLESRLRLAKVS"
     misc_feature    1377033..1378661
                     /locus_tag="Smed_4873"
                     /note="Na+/phosphate symporter [Inorganic ion transport
                     and metabolism]; Region: NptA; COG1283"
                     /db_xref="CDD:224202"
     misc_feature    1377078..1377491
                     /locus_tag="Smed_4873"
                     /note="Na+/Pi-cotransporter; Region: Na_Pi_cotrans;
                     pfam02690"
                     /db_xref="CDD:202351"
     misc_feature    1377462..>1377713
                     /locus_tag="Smed_4873"
                     /note="Na+/Pi-cotransporter; Region: Na_Pi_cotrans;
                     pfam02690"
                     /db_xref="CDD:202351"
     misc_feature    1378071..1378313
                     /locus_tag="Smed_4873"
                     /note="PhoU domain; Region: PhoU; pfam01895"
                     /db_xref="CDD:216770"
     misc_feature    1378410..1378607
                     /locus_tag="Smed_4873"
                     /note="PhoU domain; Region: PhoU; pfam01895"
                     /db_xref="CDD:216770"
     gene            1378806..1380002
                     /locus_tag="Smed_4874"
                     /db_xref="GeneID:5318921"
     CDS             1378806..1380002
                     /locus_tag="Smed_4874"
                     /note="catalyzes the formation of phosphonoacetaldehyde
                     from 2-aminoethylphosphonate and pyruvate"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="YP_001313591.1"
                     /db_xref="GI:150376995"
                     /db_xref="InterPro:IPR000192"
                     /db_xref="InterPro:IPR012703"
                     /db_xref="GeneID:5318921"
                     /translation="MPADAKTNNALEAPRLGEPYLLTPGPLTTAFSVKEAMLRDWGSW
                     DGDFRAMTAELRRELLAIAEDETGEFDCVPMQGSGSFSVEAMLGSFVPRDGKVLVLMN
                     GAYGQRIAQTLKYLGRAYVAVDKGDYMPPRGSEVAAALDADPAITHVVVVHCETSSGI
                     LNPLKEISEAVYSRGRKLLVDSMSAFGAVPAGVLDFRYEAIVSSANKCIEGVPGFGFV
                     LARKSELEAAKDRSHSLSLDVHAQWAYLNKTGQWRFTPPTHVVAAFLEALRLHRKEGG
                     VAGRGSRYAQNRDIMVSGMRQLGFETLLGDQWLSPIIVTFFSPAHPNFKFERFYELMK
                     ARGFIIYPGKLTVVDSFRIGCIGQMDGHVMRKVVAGAAESLAEMGVDSAAPPALALAE
                     RARLAA"
     misc_feature    1378845..1379951
                     /locus_tag="Smed_4874"
                     /note="2-aminoethylphosphonate--pyruvate transaminase;
                     Provisional; Region: PRK13479"
                     /db_xref="CDD:184076"
     misc_feature    order(1379040..1379045,1379052..1379054,1379259..1379261,
                     1379346..1379348,1379355..1379357,1379415..1379417,
                     1379424..1379426)
                     /locus_tag="Smed_4874"
                     /note="pyridoxal 5'-phosphate binding pocket [chemical
                     binding]; other site"
                     /db_xref="CDD:99742"
     misc_feature    1379424..1379426
                     /locus_tag="Smed_4874"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99742"
     gene            1380029..1381303
                     /locus_tag="Smed_4875"
                     /db_xref="GeneID:5318922"
     CDS             1380029..1381303
                     /locus_tag="Smed_4875"
                     /note="TIGRFAM: phosphonoacetate hydrolase;
                     PFAM: type I phosphodiesterase/nucleotide pyrophosphatase;
                     KEGG: sme:SMb21538 putative phosphonoacetate hydrolase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetate hydrolase"
                     /protein_id="YP_001313592.1"
                     /db_xref="GI:150376996"
                     /db_xref="InterPro:IPR000834"
                     /db_xref="InterPro:IPR002591"
                     /db_xref="InterPro:IPR012710"
                     /db_xref="GeneID:5318922"
                     /translation="MNQMSKISVTVNGRRYPWPRVPAIAICLDGCEPAYLDAAMEAGL
                     MPALKRIKERGAVRLAHSVIPSFTNPNNLSIATGTPPAVHGICGNYLYEPATGEEVMM
                     NDPKFLRAPTIFQAFYDAGARVAVVTAKDKLRALLGKGLRFDEERAICFSSEKSDKAT
                     PEEHGIDNASGWLGRPVPEVYSAALSEFVFAAGVKLLKEFHPDIMYLTTTDYVQHKYA
                     PGVAEANAFYAMFDRYLSELDGLGAAIVVTADHGMKPKHKADGSPDVIYVQDLLDEWL
                     GEEAARVILPITDPYVVHHGALGSFATAYLPGQCDRGEIIDRLKALDGIDVVLDREEA
                     CRRFELPEDRIGDIVLVSSENKTLGTSEHRHDLAALDEPLRSHGGLTEQEVPFIVNRV
                     LPDLPGAPCLRNFDAFFYAVAAAALISAEDAI"
     misc_feature    1380029..1381228
                     /locus_tag="Smed_4875"
                     /note="Uncharacterized proteins of the AP superfamily
                     [General function prediction only]; Region: COG1524"
                     /db_xref="CDD:224441"
     misc_feature    1380053..1381207
                     /locus_tag="Smed_4875"
                     /note="phosphonoacetate hydrolase; Region: hydr_PhnA;
                     TIGR02335"
                     /db_xref="CDD:131388"
     gene            1381300..1382757
                     /locus_tag="Smed_4876"
                     /db_xref="GeneID:5318923"
     CDS             1381300..1382757
                     /locus_tag="Smed_4876"
                     /note="PFAM: aldehyde dehydrogenase;
                     KEGG: sme:SMb21539 putative aldehyde dehydrogenase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="YP_001313593.1"
                     /db_xref="GI:150376997"
                     /db_xref="InterPro:IPR002086"
                     /db_xref="GeneID:5318923"
                     /translation="MTKPEVSIAVRHEPMRIAGQLIDTDDRIEVRYPWNNTVVGTVPA
                     GRAEHAREAFAIAAAYQPKLTRYERQKILLTAAETLASRKEEISDVITLELGISKTDS
                     LYEVGRAFDVFTLAGQMCIHDDGEIFSCDLTPHGKARKIFTTREPLTAISAITPFNHP
                     LNMVAHKVAPAIATNNCVVVKPTELTPITALLLADILYEAGLPPEMLSVVTGWPADIG
                     MEMITNPYIDLVTFTGSVPVGKLIAANAHYKRQVLELGGNDPLIILNDLSDDDLARAA
                     DLAVAGATKNSGQRCTAVKRILCQESVADRFVPMVLERAKRLRFGDPMDRSTDLGTVI
                     HEKAAALFEERVLSAAGEGADILYHPGRSGALLPPIVVDRVPHHSDLVLEETFGPIIP
                     IVRVPDDDEATIALSNSTAFGLSSGVCTNDYRRMQKYIAGLKVGTVNVWEVPGYRIEM
                     SPFGGIKDSGNGYKEGVIEAMKSFTNVKTFSLPWP"
     misc_feature    1381327..1382751
                     /locus_tag="Smed_4876"
                     /note="putative phosphonoacetaldehyde dehydrogenase;
                     Region: PhnAcAld_DH; TIGR03250"
                     /db_xref="CDD:132294"
     misc_feature    1381381..1382745
                     /locus_tag="Smed_4876"
                     /note="Streptomyces putative phosphonoformaldehyde
                     dehydrogenase PhpJ-like; Region: ALDH_PhpJ; cd07146"
                     /db_xref="CDD:143464"
     misc_feature    order(1381759..1381773,1381795..1381797,1381840..1381842,
                     1381846..1381851,1381993..1382004,1382011..1382013,
                     1382020..1382025,1382059..1382067,1382170..1382172,
                     1382452..1382454,1382458..1382460,1382539..1382541,
                     1382656..1382658)
                     /locus_tag="Smed_4876"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:143464"
     misc_feature    order(1381771..1381773,1382059..1382061,1382161..1382163,
                     1382170..1382172)
                     /locus_tag="Smed_4876"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143464"
     gene            1382989..1384011
                     /locus_tag="Smed_4877"
                     /db_xref="GeneID:5318924"
     CDS             1382989..1384011
                     /locus_tag="Smed_4877"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb21540 putative iron uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313594.1"
                     /db_xref="GI:150376998"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="InterPro:IPR011587"
                     /db_xref="GeneID:5318924"
                     /translation="MPFSKAFLGAATAFLLASTAAYAEAELTVYTSVEAVDLDRYKET
                     FEKAHPDIKINWVRDSTGVMTAKLLAEKDNPQADVVWGVAATSLLLLKSEGMLEPYAP
                     KNVEALDPRFVDGDKPPSWVGMDAYVAALCYNTVEAEKLGLTPPTSWKDLTKPEYKGH
                     VVMPNPNSSGTGFLDVSAWLQTFGEEEAWSFMDALHENIAAYTHSGSKPCKMAASGET
                     VIGVSFEFPGAKAKTSGAPIDIIFPAEGSGWEAEATAIIAGTANLEAAKTLVDWSISK
                     EANEMYNVGYAVVAYPGVAKPIENLPDDVAEKMIENDFEWAANNRARILKEWQKRYDA
                     KSEPKS"
     sig_peptide     1382989..1383060
                     /locus_tag="Smed_4877"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.982 at
                     residue 24"
     misc_feature    1383070..1383999
                     /locus_tag="Smed_4877"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; cl17199"
                     /db_xref="CDD:247753"
     gene            1384151..1385314
                     /locus_tag="Smed_4878"
                     /db_xref="GeneID:5318925"
     CDS             1384151..1385314
                     /locus_tag="Smed_4878"
                     /note="PFAM: ABC transporter related; Transport-associated
                     OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21541 putative iron ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313595.1"
                     /db_xref="GI:150376999"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5318925"
                     /translation="MKHATAPAEPAMPVSANRQSERRPFLEISGLWKAYGDFVALRDI
                     DLQVKEGEFVCFLGPSGCGKTTLLRAIAGLDIQSRGAIRQAGQDISRLPPAQRDYGIV
                     FQSYALFPNLTIEKNIAFGLENIGRPRREIASRVSDLLDLVGLSSQGRKYPAQLSGGQ
                     QQRVALARAMAISPGLLLLDEPLSALDAKVRVHLRHEIKELQRKLGVTTIMVTHDQEE
                     ALSMADRIVVMNQGGIEQVGTPTEIYRHPRTLFVADFIGETNQFPATVGKGAQVEIGH
                     TRFACAEHLLPAGAAVVAAVRPADIIPHGADAHRATGLEAVGNADNLIDAHVEDMEFL
                     GMFWRTRLSAPRLKETPLVADFSTNAVRRLCIEIGSAIQVEIPQERLLLFAKA"
     misc_feature    1384217..1385305
                     /locus_tag="Smed_4878"
                     /note="putative 2-aminoethylphosphonate ABC transporter,
                     ATP-binding protein; Region: PhnT2; TIGR03265"
                     /db_xref="CDD:234152"
     misc_feature    1384226..1384921
                     /locus_tag="Smed_4878"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    1384322..1384345
                     /locus_tag="Smed_4878"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    order(1384331..1384336,1384340..1384348,1384460..1384462,
                     1384688..1384693,1384790..1384792)
                     /locus_tag="Smed_4878"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    1384451..1384462
                     /locus_tag="Smed_4878"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    1384616..1384645
                     /locus_tag="Smed_4878"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    1384676..1384693
                     /locus_tag="Smed_4878"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    1384700..1384711
                     /locus_tag="Smed_4878"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    1384778..1384798
                     /locus_tag="Smed_4878"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     gene            1385320..1387353
                     /locus_tag="Smed_4879"
                     /db_xref="GeneID:5318041"
     CDS             1385320..1387353
                     /locus_tag="Smed_4879"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21542 putative iron uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313596.1"
                     /db_xref="GI:150377000"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318041"
                     /translation="MTLAVDFLPPGRALRQQISDDDRLKRAVMFVVGIYLVIALAIPL
                     FVMLSKSLSTYTFDLHQFEFQVSDESGGGWSDPVTAAALNTAIAAFPESDLEAGADGR
                     LQAAKLFADFSFRSPVRYRIRGTSEEAHFLAGSQLVRGTEWKEYDSNHFRRVMLRPSR
                     SVGLSNFTEYFSTPSLVRSIKNSVMIALISTAVTLTVAFGLAYALNRSRMRGKGAFKL
                     IVTIPILVPSLLPGIALVYLFGNQGVFKDLLLGHSIYGPLGIVVGSVFFTLPHAFLII
                     STALSVADARHYEAATSLRASRWRTFWTVTVPGARYGLISAAFVVFTLVITDFGLPKV
                     IGGQYGMLAVDIYKQVIGQQNFEMGAVVSVILLIPAFLAFAVDRMTQRRQVALLSARA
                     VPFEPKPRRGFDAACFAFCSLVAIFVLGMIGMCQVAALVKFWPYDLSLSLRNYAFDLM
                     DGGGWDAYYNSIRLALMTAVIGSLIVFTGAYMVEKTKGFGLGRGAFHMLAMLPMAVPG
                     MVLGLAYIFFFNNPGNPLHGIYGTMAILVLCTVTHFYTVAHLTALTALKQLDPEFEAV
                     ADSLKIPFYKLFFRVTLPVCLPALLEIAIYLFVNAMTTVSAVVFLYATDTKLASVAIL
                     NMDDAGDIAPAAAMGMMIFYTNVAAKLLHAVVARLLLARTQGWRQVAQTAVPA"
     misc_feature    1385803..1387323
                     /locus_tag="Smed_4879"
                     /note="putative 2-aminoethylphosphonate ABC transporter,
                     permease protein; Region: PhnU2; TIGR03262"
                     /db_xref="CDD:132306"
     misc_feature    1385857..1386432
                     /locus_tag="Smed_4879"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1385905..1385910,1385917..1385922,1385935..1385937,
                     1385965..1385976,1385980..1386009,1386016..1386021,
                     1386025..1386027,1386115..1386120,1386124..1386126,
                     1386130..1386132,1386139..1386144,1386148..1386150,
                     1386160..1386165,1386172..1386174,1386223..1386225,
                     1386265..1386270,1386277..1386279,1386298..1386309,
                     1386316..1386321,1386346..1386351,1386382..1386387,
                     1386394..1386399,1386403..1386408,1386415..1386420,
                     1386427..1386432)
                     /locus_tag="Smed_4879"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1385983..1386027,1386298..1386315)
                     /locus_tag="Smed_4879"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1386025..1386027,1386100..1386102,1386316..1386318,
                     1386340..1386342,1386349..1386351,1386382..1386384)
                     /locus_tag="Smed_4879"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1386175..1386213,1386229..1386234,1386244..1386246)
                     /locus_tag="Smed_4879"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     misc_feature    1386697..1387248
                     /locus_tag="Smed_4879"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1386739..1386744,1386748..1386753,1386766..1386768,
                     1386805..1386816,1386820..1386849,1386856..1386861,
                     1386865..1386867,1386940..1386945,1386949..1386951,
                     1386955..1386957,1386964..1386969,1386973..1386975,
                     1386988..1386993,1387000..1387002,1387051..1387053,
                     1387093..1387098,1387105..1387107,1387126..1387137,
                     1387144..1387149,1387186..1387191,1387219..1387224,
                     1387231..1387236,1387240..1387245)
                     /locus_tag="Smed_4879"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1386823..1386867,1387126..1387143)
                     /locus_tag="Smed_4879"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1386865..1386867,1386925..1386927,1387144..1387146,
                     1387180..1387182,1387189..1387191,1387219..1387221)
                     /locus_tag="Smed_4879"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1387003..1387041,1387057..1387062,1387072..1387074)
                     /locus_tag="Smed_4879"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1387380..1388714)
                     /locus_tag="Smed_4880"
                     /db_xref="GeneID:5318042"
     CDS             complement(1387380..1388714)
                     /locus_tag="Smed_4880"
                     /note="PFAM: protein of unknown function DUF900 hydrolase
                     family protein;
                     KEGG: sme:SMa0599 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313597.1"
                     /db_xref="GI:150377001"
                     /db_xref="InterPro:IPR010297"
                     /db_xref="GeneID:5318042"
                     /translation="MANRRSRDFLVASSVPVVRLQRMILCLAIAALSGCGGHPKGVLT
                     PVADSAPTASRVDMLITTTRGRSEVAGEMFTGERARAPAFANITVSIPPVRKAGEVAW
                     PKKLPSNPATDFATLKADDLTRDGAKDWLNTTVRKSPDRSVLVFIHGFNNRFEDSVYR
                     FAQIVHDSGVHSAPVLVTWPSRGSLLAYGYDRESTNYTRNALESLFQYLAADKEVKEV
                     SILAHSMGNWLTLEALRQMAIRNDGLPEKFKNVMLAAPDVDVDVFRSQIEDMGRQHPR
                     FTLFVSRDDRALAFSRRVWGDIPRLGSIDPEADPYKQELADNEITVIDLTKVKAGDGM
                     HHGKFAESPEVVRLIGARISEGQPLTDSRMGLGDHLIAGTTGAAAAAGSAAGLILAAP
                     VAAIDPHSRDNYANHVGAAMGQSHGKQQIAVKDCSKQARERDAASTSPCRSW"
     misc_feature    complement(1387605..1388621)
                     /locus_tag="Smed_4880"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: COG4782"
                     /db_xref="CDD:227121"
     gene            complement(1388942..1390759)
                     /locus_tag="Smed_4881"
                     /db_xref="GeneID:5318043"
     CDS             complement(1388942..1390759)
                     /locus_tag="Smed_4881"
                     /note="KEGG: sme:SMa0601 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313598.1"
                     /db_xref="GI:150377002"
                     /db_xref="InterPro:IPR013026"
                     /db_xref="GeneID:5318043"
                     /translation="MVTAVTHGSGGAEPLPYPLPGPDEIRAQLARVISSPEFPKAGRG
                     AAFLTFVVEEAIAGRAHRLKGYTVAIEVFKRSDTFTQDDPVVRIEAGRLRRTLERYYL
                     VAGQGDPIRIDIPKGGYAPSFAWNDAAVTGRKEAAAENSDERPAQGRLRTPLPILAGL
                     VGVVITAVLTYWATDRFIAGTRQSGFSAVPDEPTLVIAPFANLGDGPQSELYTVGLTE
                     ELLTALPRFKEIRVFGRETSKSLAPEVQASEVRGGLGARYLLAGGVRVSGPRVRVTAR
                     LVDTSDGAILWSQNYDDDLTTRELFAIQSDVASKVATAVAQPYGIIAQAVTAKPPPDD
                     LGVYDCTLRFYAYRAELSPEAHLSARACLESAVARYPAYATAWAMLSIAYLDEDRFRY
                     NLNPAQREPMERALHAARRAIELEPDNTRALQSLMTALFFNQQLAEALEAGEEALATN
                     PNDTELLAEFGTRLALCGQWKRGADLLDRALALNPGGAAYYHGTRALAAYMLDDHAKA
                     VSLIRKADLQKFPLFHIVAAAIYAEAGLIDDARREGTIFTKIRPEYIRDIINENRKRN
                     IQPKDSIRMIASLRKAGVPVPDAAGIEAELLKSAVTDRR"
     misc_feature    complement(1389797..1390219)
                     /locus_tag="Smed_4881"
                     /note="Predicted integral membrane protein [Function
                     unknown]; Region: COG5616"
                     /db_xref="CDD:227903"
     misc_feature    complement(<1389467..1389685)
                     /locus_tag="Smed_4881"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cl02429"
                     /db_xref="CDD:243034"
     misc_feature    complement(order(1389479..1389481,1389524..1389526,
                     1389533..1389535,1389545..1389547,1389617..1389619,
                     1389662..1389664,1389671..1389673,1389683..1389685))
                     /locus_tag="Smed_4881"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     misc_feature    complement(order(1389473..1389478,1389485..1389490,
                     1389602..1389607,1389614..1389619,1389623..1389628))
                     /locus_tag="Smed_4881"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     gene            1391076..1392521
                     /locus_tag="Smed_4882"
                     /db_xref="GeneID:5318044"
     CDS             1391076..1392521
                     /locus_tag="Smed_4882"
                     /note="PFAM: protein of unknown function DUF1214; protein
                     of unknown function DUF1254;
                     KEGG: sme:SMa0610 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313599.1"
                     /db_xref="GI:150377003"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="InterPro:IPR010621"
                     /db_xref="InterPro:IPR010679"
                     /db_xref="GeneID:5318044"
                     /translation="MLTKRDLLHAAAIAAAVAATAARSTPAIAQDKAGWPSVLEAKDI
                     AEEGLIYGLPLVMNYAVMQEFAVDRNSGQFKAPFNEINNMHHVATPADTAIITPNSDT
                     PYSFVWLDLRAEPMVLSVPAIDKDRYYSIQLIDGNTYNFGYIGTRATGTEPGDYLVVG
                     PDWKGETPAGIKKVFRSTTPFTFTAIRTQLFNRNDMPRVEKIQAGYTAQPLSAFLKQP
                     APPASPKIDFLPATTAGIKDNFFRYLDASLQFVPETSRDKAIRARLAKIGIGPGKTFE
                     FEDLSLEHKDAIRVAMKQGNDKVDKWLTNGNKNINGWNIGSFFGDEAFFNGDWMMRAG
                     AAKGGLYGNDAVEAMYPYTRTDTTGEPLDGSKHKYTITFAPGQLPPVNAFWSVTMYDG
                     KSQFLVKNPIDRYLINSPMLPGMKRAPDGSLTLYIQKDSPGADKEANWLPAPDGTIYL
                     VMRLYWPKPTPPSILPAGEGTWQPPGVKRVS"
     sig_peptide     1391076..1391165
                     /locus_tag="Smed_4882"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.952 at
                     residue 30"
     misc_feature    1391178..1392518
                     /locus_tag="Smed_4882"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG5361"
                     /db_xref="CDD:227659"
     misc_feature    1391310..1391696
                     /locus_tag="Smed_4882"
                     /note="Protein of unknown function (DUF1254); Region:
                     DUF1254; pfam06863"
                     /db_xref="CDD:219206"
     misc_feature    <1392069..1392440
                     /locus_tag="Smed_4882"
                     /note="Protein of unknown function (DUF1214); Region:
                     DUF1214; cl08447"
                     /db_xref="CDD:244961"
     gene            1392681..1393013
                     /locus_tag="Smed_4883"
                     /db_xref="GeneID:5318045"
     CDS             1392681..1393013
                     /locus_tag="Smed_4883"
                     /note="KEGG: rle:RL2265 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313600.1"
                     /db_xref="GI:150377004"
                     /db_xref="GeneID:5318045"
                     /translation="MVRYRRKTAGPPWPGKRGSHIMGYDVAFTKRCFPARVGLIDELA
                     ARNESFRDLCYDFATAEEVRLAWETASGPEKDERHAESVELVDCLRTEIEAALDDAAV
                     VPFQRRRT"
     gene            1393178..1393402
                     /locus_tag="Smed_4884"
                     /db_xref="GeneID:5318046"
     CDS             1393178..1393402
                     /locus_tag="Smed_4884"
                     /note="KEGG: sme:SMc00958 hypothetical/unknown protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313601.1"
                     /db_xref="GI:150377005"
                     /db_xref="GeneID:5318046"
                     /translation="MTMNDWRADLRLGLENLVDAAVVAGAHQRDVYAAILDEVERLRL
                     AYERDPDPADDLSEQIVEEPSNNWPAAEQD"
     gene            1393572..1394573
                     /locus_tag="Smed_4885"
                     /db_xref="GeneID:5318047"
     CDS             1393572..1394573
                     /locus_tag="Smed_4885"
                     /note="PFAM: Integrase catalytic region;
                     KEGG: sme:SMa2047 TRm24 putative transposase"
                     /codon_start=1
                     /transl_table=11
                     /product="integrase catalytic region"
                     /protein_id="YP_001313602.1"
                     /db_xref="GI:150377006"
                     /db_xref="InterPro:IPR001584"
                     /db_xref="GeneID:5318047"
                     /translation="MSQCYLQLTLPDRRRVHQLLERKVPIAEIARQLGRHRSTIYREL
                     KRNTFHDAEFPEYSGYYSGIANDISKERRRRLRKLSRHAQLRELVIEQLKALWSPEQI
                     AGRLLADGVSAVRVCTETIYRFIYSKEDYALELYQHLPEGRRKRRPRRSRKPRDGSIP
                     LDCRISQRPDFIADRSQFGHWEGDLLIFRRDLGEANVTSLVERKSRYTVMIKNGSRHS
                     RPLIDKIIDAFSPLPAFARQSFTFDRGTEFRGFKALEDGLGARSWFCDPNSPWQKGAV
                     ENTNKRIRRFVPSDTDLSAVNQPQLVALAHHLNSLPRKCLGYRTPAEVFMAHLRDCG"
     misc_feature    1393572..1394570
                     /locus_tag="Smed_4885"
                     /note="Transposase and inactivated derivatives, IS30
                     family [DNA replication, recombination, and repair];
                     Region: Tra8; COG2826"
                     /db_xref="CDD:225382"
     misc_feature    1393593..1393703
                     /locus_tag="Smed_4885"
                     /note="Helix-turn-helix domain of Hin and related
                     proteins, a family of DNA-binding domains unique to
                     bacteria and represented by the Hin protein of Salmonella.
                     The basic HTH domain is a simple fold comprised of three
                     core helices that form a right-handed...; Region:
                     HTH_Hin_like; cd00569"
                     /db_xref="CDD:119388"
     misc_feature    order(1393683..1393688,1393692..1393700)
                     /locus_tag="Smed_4885"
                     /note="DNA-binding interface [nucleotide binding]; DNA
                     binding site"
                     /db_xref="CDD:119388"
     misc_feature    <1393818..1393946
                     /locus_tag="Smed_4885"
                     /note="Homeodomain-like domain; Region: HTH_32; pfam13565"
                     /db_xref="CDD:222226"
     misc_feature    1394103..1394432
                     /locus_tag="Smed_4885"
                     /note="Integrase core domain; Region: rve; pfam00665"
                     /db_xref="CDD:216050"
     gene            1394699..1396072
                     /locus_tag="Smed_4886"
                     /db_xref="GeneID:5318048"
     CDS             1394699..1396072
                     /locus_tag="Smed_4886"
                     /note="PFAM: Integrase catalytic region;
                     KEGG: ret:RHE_PA00137 putative insertion sequence
                     transposase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="integrase catalytic region"
                     /protein_id="YP_001313603.1"
                     /db_xref="GI:150377007"
                     /db_xref="InterPro:IPR001584"
                     /db_xref="GeneID:5318048"
                     /translation="MGLIAMSERDLQRIEVLSKVIDGRMTLVTAAHVLGLSTRQVRRL
                     LERIRTDGAASIRHKAIGRPSNNRISDGVRDYAVTLVRERYADFGPTLAAEKLAERDG
                     LRVSRETLRKWMSEAGLWLSRKQRRTFHQPRLRREAYGELVQIDGSEHRWFEDRGDPC
                     SLLVFIDDATGKLMQLRFVRSESAFSYFEALELYLKNHGAPVAFYSDKHSVFRVAKKD
                     AKGGQGMTQFGRALSELNIEILCANSSQAKGRVERMNRTLQDRLIKDLRLEGICGMDD
                     GNAFLPRFMEGYNRQFAITPARPDDLHRSLNLAPDRLKEILCKREQRYVGAQLTFSFE
                     RQRIMLEETEVTRGLVGRYVETYAYADGRLDVRWKGHCLPYRVFDKDQRVTHAAITEN
                     KRLGDVLAYIKARQDERPAPKVKTNSEKIGYRPRGRKPGKRTDFTNDPAVIARRRQAL
                     SELDAAE"
     misc_feature    1394732..1394893
                     /locus_tag="Smed_4886"
                     /note="Helix-turn-helix domain; Region: HTH_28; pfam13518"
                     /db_xref="CDD:222191"
     misc_feature    1394735..1395052
                     /locus_tag="Smed_4886"
                     /note="Winged helix-turn helix; Region: HTH_29; pfam13551"
                     /db_xref="CDD:222216"
     misc_feature    1394816..1395040
                     /locus_tag="Smed_4886"
                     /note="Homeodomain-like domain; Region: HTH_32; pfam13565"
                     /db_xref="CDD:222226"
     misc_feature    1395116..1395484
                     /locus_tag="Smed_4886"
                     /note="Integrase core domain; Region: rve; pfam00665"
                     /db_xref="CDD:216050"
     gene            complement(1396401..1398509)
                     /locus_tag="Smed_4887"
                     /db_xref="GeneID:5318049"
     CDS             complement(1396401..1398509)
                     /locus_tag="Smed_4887"
                     /note="PFAM: NADH:flavin oxidoreductase/NADH oxidase;
                     FAD-dependent pyridine nucleotide-disulphide
                     oxidoreductase;
                     KEGG: sme:SMb21570 putative NADH-dependent oxidase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="YP_001313604.1"
                     /db_xref="GI:150377008"
                     /db_xref="InterPro:IPR000759"
                     /db_xref="InterPro:IPR001100"
                     /db_xref="InterPro:IPR001155"
                     /db_xref="InterPro:IPR001327"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="GeneID:5318049"
                     /translation="MVSFLTQVYIPGYFLRTYLTGAWQMSNDPLLQPYQLKHLTLRNR
                     IIVTAHEPAYPEDGMPKARYRAYTVERAKGGVALTMTAGSAAISRDSPPVFNNLLAYK
                     DEIVPWIREMTDAVHEQGAAIMIQLTHLGRRTRWDKGDWLPVVAPSHLREASHRAFPK
                     KIEDWDIERIIKDFADAAERMKAGGMDGVELEAYGHLLDQFASPLTNELDGPYGGSLD
                     NRMRFCFDVLRAIRTRVGDDFILGVRYTADECLPGGTGKAEGLEISKRLKESGLIDYL
                     NVIRGHIDTDAGLTDVIPIQGMANSPHLDFAGEIRAATDFPTFHAAKIPDVATARHAI
                     ASGKIDMVGMTRAHMTDPHLVRKIVEKREDDIRPCVGANYCLDRIYQGGAAYCIHNAA
                     TGRELTMPHSIAKADRRRKVVIVGTGPAGLEAARVAGERGHEVVVFEAASDPGGQVRL
                     TAQSPRRREMISIIDWRMGQCEKLGVTFHFNTWAEAETIRAERPDVVIIATGGLPHTE
                     VLSKGNELVVSAWDIISGDVKPGTNVLIFDDAGDHAALQAAEFLASAGARVEIMTPDR
                     SFAPEVMAMNLVPYMRSLQKLDVTFTVTYRLEAVERSGNQLVAHVGSDYGGIARQQTF
                     DQVVVNHGTIPLDDLYFELKPFSSNRGEIDHERLIAGEPQSVVRNPDGQFQLFRIGDA
                     VAARNTHAAIYDALRLLKDV"
     misc_feature    complement(1396419..1398422)
                     /locus_tag="Smed_4887"
                     /note="mycofactocin system FadH/OYE family oxidoreductase
                     2; Region: mycofact_OYE_2; TIGR03997"
                     /db_xref="CDD:234436"
     misc_feature    complement(1397391..1398422)
                     /locus_tag="Smed_4887"
                     /note="Old yellow enzyme (OYE)-related FMN binding domain,
                     group 3. Each monomer of OYE contains FMN as a
                     non-covalently bound cofactor, uses NADPH as a reducing
                     agent with oxygens, quinones, and alpha,beta-unsaturated
                     aldehydes and ketones, and can act as...; Region:
                     OYE_like_3_FMN; cd04734"
                     /db_xref="CDD:240085"
     misc_feature    complement(order(1397472..1397477,1397778..1397780,
                     1397922..1397924,1398132..1398134,1398261..1398263,
                     1398357..1398359,1398363..1398365))
                     /locus_tag="Smed_4887"
                     /note="putative active site [active]"
                     /db_xref="CDD:240085"
     misc_feature    complement(order(1397472..1397477,1397778..1397780,
                     1398132..1398134,1398261..1398263,1398357..1398359,
                     1398363..1398365))
                     /locus_tag="Smed_4887"
                     /note="putative FMN binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240085"
     misc_feature    complement(order(1397922..1397924,1397928..1397930))
                     /locus_tag="Smed_4887"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:240085"
     misc_feature    complement(1397922..1397924)
                     /locus_tag="Smed_4887"
                     /note="putative catalytic residue [active]"
                     /db_xref="CDD:240085"
     misc_feature    complement(<1397163..1397270)
                     /locus_tag="Smed_4887"
                     /note="NAD(P)-binding Rossmann-like domain; Region:
                     NAD_binding_8; pfam13450"
                     /db_xref="CDD:205628"
     gene            1398593..1399222
                     /locus_tag="Smed_4888"
                     /db_xref="GeneID:5318050"
     CDS             1398593..1399222
                     /locus_tag="Smed_4888"
                     /note="PFAM: regulatory protein TetR;
                     KEGG: sme:SMb21571 putative transcriptional regulator TetR
                     family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="YP_001313605.1"
                     /db_xref="GI:150377009"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="GeneID:5318050"
                     /translation="MNDSGWRGSPDVWLGAAYESLLEAGVDAVKIQPLAKKLNLSRTS
                     FYWFFKDREELLDALVIRWREKNTGNLIKQAEAYAETVAEAMLNVFDCWLDSSLFDSQ
                     FEFAVRSWAIQSPEILAEVQRADQQRLEALTRMFLRFGQNEARADVRARTIYLVQIGY
                     ISMQTKEDTTVRMKRIPEYVEIFTGQAPEQRELDRFFARHGYSDSKKGA"
     misc_feature    1398632..1399117
                     /locus_tag="Smed_4888"
                     /note="Transcriptional regulator [Transcription]; Region:
                     AcrR; COG1309"
                     /db_xref="CDD:224228"
     misc_feature    1398632..1398769
                     /locus_tag="Smed_4888"
                     /note="Bacterial regulatory proteins, tetR family; Region:
                     TetR_N; pfam00440"
                     /db_xref="CDD:201228"
     gene            1399372..1400373
                     /locus_tag="Smed_4889"
                     /db_xref="GeneID:5318051"
     CDS             1399372..1400373
                     /locus_tag="Smed_4889"
                     /note="PFAM: Substrate-binding region of ABC-type glycine
                     betaine transport system;
                     KEGG: sme:SMb21572 putative amino acid uptake ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="YP_001313606.1"
                     /db_xref="GI:150377010"
                     /db_xref="InterPro:IPR007210"
                     /db_xref="GeneID:5318051"
                     /translation="MNKLLASTCLMLCLTAGASASNAAECGSVTIASMNWQSAEVLSN
                     LDKFILNEGYGCSAEITIGDTVPTITSMAEKGQPDIAPEAWIDLLPDVVKKGQDDGRI
                     VTVGSPLPDGGVQGWWIPKYLADAHPDIKTIGDALKHPELFPAPEDSSKGALLNGPQG
                     WGGTVVTTQLFNAFDGEKAGFTLIDTGSAAGLDGAIAKAYERKEGLFTYYWSPTALLG
                     KYEMVKLEPGVPHDSAEWKRCNTVADCPDPKPNAWPVDTIVTLVAKPFSERVGPEVMD
                     YLTKRSWSNETVSKLMAWMTDNQASGEEGAKRFLEENQDMWSKWVSPEAAEKIKAAL"
     sig_peptide     1399372..1399443
                     /locus_tag="Smed_4889"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.938 at
                     residue 24"
     misc_feature    1399381..1400358
                     /locus_tag="Smed_4889"
                     /note="ABC-type proline/glycine betaine transport systems,
                     periplasmic components [Amino acid transport and
                     metabolism]; Region: ProX; COG2113"
                     /db_xref="CDD:225024"
     misc_feature    1399450..1400307
                     /locus_tag="Smed_4889"
                     /note="Substrate binding domain of ABC-type glycine
                     betaine transport system; Region: OpuAC; pfam04069"
                     /db_xref="CDD:217871"
     gene            1400522..1401505
                     /locus_tag="Smed_4890"
                     /db_xref="GeneID:5318228"
     CDS             1400522..1401505
                     /locus_tag="Smed_4890"
                     /note="PFAM: Peptidoglycan-binding domain 1 protein;
                     ErfK/YbiS/YcfS/YnhG family protein;
                     KEGG: sme:SMb21573 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ErfK/YbiS/YcfS/YnhG family protein"
                     /protein_id="YP_001313607.1"
                     /db_xref="GI:150377011"
                     /db_xref="InterPro:IPR002477"
                     /db_xref="InterPro:IPR005490"
                     /db_xref="GeneID:5318228"
                     /translation="MFMKIIVFAAASLTMGLTATALAEELQPEAINTAPIASIAPERP
                     PKESPHPDPAIVHLQVLLDRAGSSPGVIDGYYGENVTKAIAGFEAMQKLPTDGKLDPE
                     VVSRLSEDKPAIQSYVITEEDTKDLVSDIPNDYSEQAEMDNLGYKSVEERLSERFHMD
                     VDLLKTLNPNSSFDTGETVWVAMPGAPKEGVVKRIEVRKRSGQVLAFAEDGAPIAVYP
                     ASIGSEASPSPSGRHKVKGVARMPPYVYDPEVNFQQADNNKPLTLPKGPNNPVGTVWI
                     DLTKPTYGIHGTPEPSLIDKAQSHGCVRLTNWDAEELAEMVKPGVITEFTD"
     sig_peptide     1400522..1400593
                     /locus_tag="Smed_4890"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.997 at
                     residue 24"
     misc_feature    1400546..>1400866
                     /locus_tag="Smed_4890"
                     /note="Putative peptidoglycan-binding domain-containing
                     protein [Cell envelope biogenesis, outer membrane];
                     Region: COG3409"
                     /db_xref="CDD:225943"
     misc_feature    1400672..1400842
                     /locus_tag="Smed_4890"
                     /note="Putative peptidoglycan binding domain; Region:
                     PG_binding_1; pfam01471"
                     /db_xref="CDD:216518"
     misc_feature    1400903..1401502
                     /locus_tag="Smed_4890"
                     /note="Uncharacterized protein conserved in bacteria
                     [Function unknown]; Region: ErfK; COG1376"
                     /db_xref="CDD:224294"
     misc_feature    1401098..1401481
                     /locus_tag="Smed_4890"
                     /note="L,D-transpeptidase catalytic domain; Region: YkuD;
                     pfam03734"
                     /db_xref="CDD:217702"
     gene            complement(1401581..1402231)
                     /locus_tag="Smed_4891"
                     /db_xref="GeneID:5318229"
     CDS             complement(1401581..1402231)
                     /locus_tag="Smed_4891"
                     /note="PFAM: Glutathione S-transferase domain;
                     KEGG: rle:RL1444 putative glutathione S-transferase I"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase domain-containing
                     protein"
                     /protein_id="YP_001313608.1"
                     /db_xref="GI:150377012"
                     /db_xref="InterPro:IPR004045"
                     /db_xref="GeneID:5318229"
                     /translation="MTITITAFERSPDRGKGLARDMRVRWALEEVGQPYDVRLLSFEE
                     MKQPAHFALHPFGQIPTYEEGDLALFESGAIVLHIAENHAGLLPDDPNARARAITWMF
                     AALNTVEPPIFDHDLARIFERDEPWYEQRLRFLKDSIGKRLGALSDRLGEAEWLDGLF
                     SAGDLLMVSVLLRSKGSGMLEDYPNLAAYVARGEARPGYKRAFEAQLAVFTAASTI"
     misc_feature    complement(1401980..1402225)
                     /locus_tag="Smed_4891"
                     /note="GST_N family, Saccharomyces cerevisiae GTT1-like
                     subfamily; composed of predominantly uncharacterized
                     proteins with similarity to the S. cerevisiae GST protein,
                     GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are
                     cytosolic dimeric proteins involved...; Region:
                     GST_N_GTT1_like; cd03046"
                     /db_xref="CDD:239344"
     misc_feature    complement(order(1402001..1402006,1402013..1402015,
                     1402142..1402147,1402154..1402159,1402163..1402168,
                     1402172..1402174))
                     /locus_tag="Smed_4891"
                     /note="putative C-terminal domain interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239344"
     misc_feature    complement(order(1402016..1402021,1402052..1402060,
                     1402172..1402174))
                     /locus_tag="Smed_4891"
                     /note="putative GSH binding site (G-site) [chemical
                     binding]; other site"
                     /db_xref="CDD:239344"
     misc_feature    complement(1401596..1402165)
                     /locus_tag="Smed_4891"
                     /note="Glutathione S-transferase [Posttranslational
                     modification, protein turnover, chaperones]; Region: Gst;
                     COG0625"
                     /db_xref="CDD:223698"
     misc_feature    complement(order(1402001..1402003,1402010..1402015,
                     1402019..1402024,1402058..1402060))
                     /locus_tag="Smed_4891"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239344"
     misc_feature    complement(1401641..1401943)
                     /locus_tag="Smed_4891"
                     /note="C-terminal, alpha helical domain of an unknown
                     subfamily 8 of Glutathione S-transferases; Region:
                     GST_C_8; cd03207"
                     /db_xref="CDD:198316"
     misc_feature    complement(order(1401785..1401787,1401797..1401799,
                     1401806..1401808,1401830..1401832,1401839..1401841,
                     1401890..1401892,1401908..1401919,1401923..1401928,
                     1401932..1401937))
                     /locus_tag="Smed_4891"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:198316"
     misc_feature    complement(order(1401713..1401718,1401725..1401730,
                     1401734..1401739,1401746..1401754,1401893..1401895,
                     1401905..1401907,1401917..1401919,1401929..1401931))
                     /locus_tag="Smed_4891"
                     /note="N-terminal domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:198316"
     misc_feature    complement(order(1401713..1401715,1401722..1401724,
                     1401890..1401895,1401902..1401907,1401917..1401919))
                     /locus_tag="Smed_4891"
                     /note="putative substrate binding pocket (H-site)
                     [chemical binding]; other site"
                     /db_xref="CDD:198316"
     gene            complement(1402319..1403518)
                     /locus_tag="Smed_4892"
                     /db_xref="GeneID:5318230"
     CDS             complement(1402319..1403518)
                     /locus_tag="Smed_4892"
                     /note="PFAM: major facilitator superfamily MFS_1;
                     KEGG: sme:SMb21575 putative transport protein"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="YP_001313609.1"
                     /db_xref="GI:150377013"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="GeneID:5318230"
                     /translation="MKSGIPAGIVAALGLTQIVGYGTLYYSFSILAPGMARDLGQTVE
                     QVFAVFSASLLVGGLSAPIMGGWMDRFGAATIMTFGSAVSAVALLLCAWSPSMPVFAI
                     AIVLLEVASGMVQYQAAFATLVEVRPKMASRSITYLTLIGGFASTIFWPIAVNLSELL
                     SWREIYVAYAGLNLLICLPLHYWILRSRKHGAVERSRIDGEAIAGALPTRVRRRGMLL
                     VSWAFALQGFTLSAILTHMVPMLGAIGFGPAAVVIGSLFGPSQVLSRLINMTLGANLL
                     PPMLATLSAVLIVAGVVVLGLSGTWLPGAVAFAICLGLGSGINSIAQGSLPLWLFGSS
                     GYGAITGRMAAARLAAAAMAPFVFSVLMERFGTNVALMANACLGAIGIAAFVAVASAA
                     KRQPGAH"
     misc_feature    complement(<1402760..1403482)
                     /locus_tag="Smed_4892"
                     /note="Major Facilitator Superfamily; Region: MFS_1;
                     pfam07690"
                     /db_xref="CDD:219516"
     misc_feature    complement(<1402961..1403458)
                     /locus_tag="Smed_4892"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    complement(order(1403081..1403083,1403099..1403104,
                     1403111..1403116,1403150..1403152,1403159..1403164,
                     1403171..1403176,1403183..1403188,1403324..1403329,
                     1403333..1403338,1403348..1403350,1403357..1403362,
                     1403369..1403371,1403420..1403425,1403429..1403437,
                     1403444..1403446))
                     /locus_tag="Smed_4892"
                     /note="putative substrate translocation pore; other site"
                     /db_xref="CDD:119392"
     gene            complement(1403519..1403884)
                     /locus_tag="Smed_4893"
                     /db_xref="GeneID:5318231"
     CDS             complement(1403519..1403884)
                     /locus_tag="Smed_4893"
                     /note="PFAM: regulatory protein ArsR;
                     KEGG: sme:SMb21576 putative regulatory protein, ArsR
                     family"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein ArsR"
                     /protein_id="YP_001313610.1"
                     /db_xref="GI:150377014"
                     /db_xref="InterPro:IPR001845"
                     /db_xref="GeneID:5318231"
                     /translation="MDEPRARLSFAALSQETRLGIVRTLVVTGPGGMAAGAIAEKVGV
                     SPSNVSFHLKELERAGLVAQRRESRSIVYSARYDALADLVTFLMEDCCVGHPSVRASL
                     NERASCRSTSPASDESGTL"
     misc_feature    complement(1403618..1403857)
                     /locus_tag="Smed_4893"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; Region: HTH_ARSR;
                     cd00090"
                     /db_xref="CDD:238042"
     misc_feature    complement(order(1403621..1403629,1403633..1403641,
                     1403645..1403650,1403705..1403707,1403804..1403806,
                     1403813..1403818,1403825..1403830,1403837..1403839,
                     1403846..1403848,1403852..1403857))
                     /locus_tag="Smed_4893"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238042"
     misc_feature    complement(order(1403666..1403674,1403687..1403695,
                     1403711..1403716,1403720..1403725,1403732..1403737,
                     1403741..1403752,1403777..1403785,1403831..1403839,
                     1403849..1403854))
                     /locus_tag="Smed_4893"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238042"
     misc_feature    complement(order(1403648..1403650,1403774..1403776,
                     1403783..1403785))
                     /locus_tag="Smed_4893"
                     /note="putative Zn2+ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:238042"
     gene            1404056..1404379
                     /locus_tag="Smed_4894"
                     /db_xref="GeneID:5318232"
     CDS             1404056..1404379
                     /locus_tag="Smed_4894"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313611.1"
                     /db_xref="GI:150377015"
                     /db_xref="GeneID:5318232"
                     /translation="MKVIATVLTAISIAGLVSGTATAACKDGTSTDTTASINAEKPGI
                     AKDGTTAPLETENNAASKDGETMPLANQQGGGDKNLATSQQDAEAQQTGEQAAAAKAD
                     DCVVE"
     sig_peptide     1404056..1404127
                     /locus_tag="Smed_4894"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.968 at
                     residue 24"
     gene            complement(1404605..1405108)
                     /locus_tag="Smed_4895"
                     /db_xref="GeneID:5318233"
     CDS             complement(1404605..1405108)
                     /locus_tag="Smed_4895"
                     /note="PFAM: Cupin 2 conserved barrel domain protein;
                     KEGG: pde:Pden_5003 cupin 2, conserved barrel domain
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="cupin"
                     /protein_id="YP_001313612.1"
                     /db_xref="GI:150377016"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="GeneID:5318233"
                     /translation="MSDHLQHPEHHDHGEDRWKHNGVRVIKGDQLDDNTAQTPGMYRQ
                     AAINHARVGAQKIWAGTVAIQPNAKTGVHHHGPLESVIFVVRGKARMRWGDRLEYVAE
                     AGPGDFIFVPPFVPHQEINADPADVLECVLVRSDNEAVVVNITDVEPVEKPEEVYWVD
                     PIHRHPG"
     misc_feature    complement(1404620..1405057)
                     /locus_tag="Smed_4895"
                     /note="Cupin domain; Region: Cupin_2; cl17218"
                     /db_xref="CDD:247772"
     gene            complement(1405172..1406377)
                     /locus_tag="Smed_4896"
                     /db_xref="GeneID:5318234"
     CDS             complement(1405172..1406377)
                     /locus_tag="Smed_4896"
                     /note="PFAM: adenylyl cyclase class-3/4/guanylyl cyclase;
                     KEGG: sme:SMc03937 putative adenylate/guanylate cyclase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenylate/guanylate cyclase"
                     /protein_id="YP_001313613.1"
                     /db_xref="GI:150377017"
                     /db_xref="InterPro:IPR001054"
                     /db_xref="GeneID:5318234"
                     /translation="MQDEEIDILRWLANAGLRGDEPNQMFRAFCERCSRAGIPISYAM
                     GLMDTLHPEFEGHAFEWRAQDNGPRPLQTYSSSDSGNVRETWESSAFNHLRQTGESEL
                     RREIGKGAPVDFYRLPELREEGCTDVIFHIERFTRKGSIGAMDAFYSVWGTDEPDGFA
                     EDQLALLRRLLPTLALALKSVGSIRIVKTLARVYLGQDAASRVIDGQVARGQAETIDA
                     IIWLSDLKDYTAIMDAARPEQIIPLLNDYSSVVIGALHRNGGNVLKLIGDGVLAIFKG
                     PDLTAAASRALQTERELRRDLDHLNRRRGARGEPSTGLYVSLHLGTVFYGNIGSRNRL
                     DFTVVGPAVNEVSRICTICKTTNNDALVSADFVNVCRPASREGLSPLGEFSLRGVSEP
                     MVLYTVNRG"
     misc_feature    complement(1405184..1405828)
                     /locus_tag="Smed_4896"
                     /note="Adenylate cyclase, family 3 (some proteins contain
                     HAMP domain) [Signal transduction mechanisms]; Region:
                     CyaA; COG2114"
                     /db_xref="CDD:225025"
     misc_feature    complement(1405184..1405729)
                     /locus_tag="Smed_4896"
                     /note="cyclase homology domain; Region: CHD; cd07302"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(1405217..1405219,1405334..1405339,
                     1405346..1405351,1405361..1405369,1405565..1405567,
                     1405574..1405582,1405586..1405588,1405691..1405708,
                     1405712..1405714))
                     /locus_tag="Smed_4896"
                     /note="nucleotidyl binding site; other site"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(1405574..1405576,1405706..1405708))
                     /locus_tag="Smed_4896"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:143636"
     misc_feature    complement(order(1405217..1405219,1405346..1405348,
                     1405355..1405366,1405397..1405399,1405406..1405408,
                     1405583..1405588,1405622..1405624,1405634..1405636,
                     1405643..1405648,1405655..1405657,1405691..1405693))
                     /locus_tag="Smed_4896"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143636"
     gene            1406561..1409044
                     /locus_tag="Smed_4897"
                     /db_xref="GeneID:5318235"
     CDS             1406561..1409044
                     /locus_tag="Smed_4897"
                     /note="TIGRFAM: ATPase, P-type (transporting), HAD
                     superfamily, subfamily IC; copper-translocating P-type
                     ATPase; heavy metal translocating P-type ATPase;
                     PFAM: Haloacid dehalogenase domain protein hydrolase;
                     Heavy metal transport/detoxification protein; E1-E2
                     ATPase-associated domain protein;
                     KEGG: sme:SMb21578 putative copper-transporting P-type
                     ATPase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="YP_001313614.1"
                     /db_xref="GI:150377018"
                     /db_xref="InterPro:IPR000579"
                     /db_xref="InterPro:IPR001757"
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006121"
                     /db_xref="InterPro:IPR006403"
                     /db_xref="InterPro:IPR006416"
                     /db_xref="InterPro:IPR008250"
                     /db_xref="GeneID:5318235"
                     /translation="MTALKQTEKSTSLPMSFDFDIEGMTCASCVRRVEKAIAAVPGVA
                     SANVNLATERATVQFNGVPETTSVLRAVEKAGYAPRIVTEEIQIEGMTCASCVSRVEK
                     ALKAVPGVADASVNLATEKATVRLVSGSAEISALAAAVKGAGYGIRKATPAEAMKEDV
                     DHRTAELRSLKSAVTISSLMTLPLFLLEMGSHFIPGVHDFIMGTIGMRNNLYLQFALA
                     TLVLFGPGLRFFRKGVPNLLRWTPDMNSLVVLGTTAAWGYSVVTTFVPAILPSGTANV
                     YYEAAAVIVTLILVGRYLESRAKGRTSQAIKRLVGLQPKTAFVLHSGEFVETEITEVV
                     TGDVIRIRPGEKIPVDGTVTDGSSYVDESMITGEPVPVQKATDSAVIGGTINKTGSIT
                     FKATKVGSDTLLAQIIRLVEAAQGSKLPIQALVDRVTAWFVPVVILAALLTFAAWYVL
                     GPSPALSFALVNAVAVLIIACPCAMGLATPTSIMVGTGRAAELGILFRKGEALQSLRD
                     ADVVAVDKTGTLTKGRPELTDLVAAEGFEPDEVLCLVASLETLSEHPIAEAIVSAAKS
                     RGIATVAVSAFEATPGFGVSGTVSGRRVLVGADRALVKNGIDITGFADEAERLGSGGK
                     SPLYAAIDGRLAAIVAVSDPVKESTPQAIKSLHALGLKVAMVTGDNRRTAEAIAKKLG
                     IDEVVAEVLPEGKVDAVRKLRQGGRSVAFIGDGINDAPALAEADVGIAVGTGTDIAIE
                     SADVVLMSGDLNGVAKALALSKATIRNIKQNLFWAFVYNISLVPVAAGVLYPVNGTLL
                     SPIFAAAAMAMSSVFVLGNALRLKSFDPA"
     misc_feature    1406603..>1406806
                     /locus_tag="Smed_4897"
                     /note="Cation transport ATPase [Inorganic ion transport
                     and metabolism]; Region: ZntA; COG2217"
                     /db_xref="CDD:225127"
     misc_feature    1406612..1406800
                     /locus_tag="Smed_4897"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1406630..1406638,1406645..1406647)
                     /locus_tag="Smed_4897"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1406804..1409026
                     /locus_tag="Smed_4897"
                     /note="Cation transport ATPase [Inorganic ion transport
                     and metabolism]; Region: ZntA; COG2217"
                     /db_xref="CDD:225127"
     misc_feature    1406813..1407004
                     /locus_tag="Smed_4897"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1406831..1406839,1406846..1406848)
                     /locus_tag="Smed_4897"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1407407..1408075
                     /locus_tag="Smed_4897"
                     /note="E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122"
                     /db_xref="CDD:215733"
     misc_feature    1408451..1408753
                     /locus_tag="Smed_4897"
                     /note="Haloacid dehalogenase-like hydrolases. The haloacid
                     dehalogenase-like (HAD) superfamily includes L-2-haloacid
                     dehalogenase, epoxide hydrolase, phosphoserine
                     phosphatase, phosphomannomutase, phosphoglycolate
                     phosphatase, P-type ATPase, and many others; Region:
                     HAD_like; cd01427"
                     /db_xref="CDD:119389"
     misc_feature    1408559..1408561
                     /locus_tag="Smed_4897"
                     /note="motif II; other site"
                     /db_xref="CDD:119389"
     gene            1409194..1409637
                     /locus_tag="Smed_4898"
                     /db_xref="GeneID:5318236"
     CDS             1409194..1409637
                     /locus_tag="Smed_4898"
                     /note="TIGRFAM: Cu(I)-responsive transcriptional
                     regulator;
                     PFAM: regulatory protein MerR; Transcription regulator
                     MerR DNA binding;
                     KEGG: sme:SMb21579 putative transcriptional regulator,
                     merR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="YP_001313615.1"
                     /db_xref="GI:150377019"
                     /db_xref="InterPro:IPR000551"
                     /db_xref="InterPro:IPR011789"
                     /db_xref="InterPro:IPR015358"
                     /db_xref="GeneID:5318236"
                     /translation="MNIGEASKVSGVSSKMIRYYEQIGLISPAVRTASSYRTYGDNDV
                     HTLRFIRRARDLGFSVEQIKELLALWRDRSRASSDVKAVALEHIAELERKIAAIQDMT
                     RTLKHLASHCHGDGRPDCPIIEEMAKGGGAAKTEINPRFGVASLK"
     misc_feature    1409194..1409574
                     /locus_tag="Smed_4898"
                     /note="Cu(I)-responsive transcriptional regulator; Region:
                     CueR; TIGR02044"
                     /db_xref="CDD:131099"
     misc_feature    1409194..1409574
                     /locus_tag="Smed_4898"
                     /note="Helix-Turn-Helix DNA binding domain of CueR-like
                     transcription regulators; Region: HTH_CueR; cd01108"
                     /db_xref="CDD:133383"
     misc_feature    order(1409197..1409205,1409245..1409247,1409296..1409304)
                     /locus_tag="Smed_4898"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:133383"
     misc_feature    order(1409338..1409340,1409347..1409349,1409359..1409364,
                     1409389..1409391,1409401..1409403,1409422..1409427,
                     1409434..1409436,1409443..1409445,1409455..1409457,
                     1409473..1409475,1409485..1409487,1409494..1409499,
                     1409518..1409520,1409533..1409547,1409551..1409553,
                     1409557..1409559,1409566..1409571)
                     /locus_tag="Smed_4898"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:133383"
     misc_feature    order(1409422..1409424,1409527..1409529,1409551..1409553)
                     /locus_tag="Smed_4898"
                     /note="copper binding site [ion binding]; other site"
                     /db_xref="CDD:133383"
     gene            1409881..1410972
                     /locus_tag="Smed_4899"
                     /db_xref="GeneID:5318237"
     CDS             1409881..1410972
                     /locus_tag="Smed_4899"
                     /note="PFAM: glycosyl transferase group 1;
                     KEGG: sme:SMb21581 putative glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 glycosyl transferase"
                     /protein_id="YP_001313616.1"
                     /db_xref="GI:150377020"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="GeneID:5318237"
                     /translation="MKIAQIAPLAERVPPKLYGGTERIVHCLTEELVKLGHDVTLFAS
                     GDSLTSAELVPCCDVALRLNPKVRDFLPHHVAMLEEVRRRAHQFDILHFHIEFLHFPL
                     IKDFAGKTVTTLHTRLDLSDVHPFYLAFPDVPLVSISEHQRTPMPPVNWRGTVLHGLD
                     PTVLPFKERPSGAYLAFLGRISPEKGPDRAIEIAVRAGMPLKIAAKVDAQDRDYWDSV
                     VEPLIRRHSNVEYVGEIGESQKADFLGNAAALLFPINWPEPFGLVMIESMACGTPVLA
                     FRYGSAPEVIDDGVSGILVDTVEQAVKRLDRVLGLNRRKVRESFEKRFTTDRMTRDYI
                     DIYRSLPSIRAPADPTPEEEPKKVGLEAA"
     misc_feature    1409881..1410894
                     /locus_tag="Smed_4899"
                     /note="This family is most closely related to the GT1
                     family of glycosyltransferases. aviGT4 in Streptomyces
                     viridochromogenes has been shown to be involved in
                     biosynthesis of oligosaccharide antibiotic avilamycin A.
                     Inactivation of aviGT4 resulted in a mutant...; Region:
                     GT1_AviGT4_like; cd03802"
                     /db_xref="CDD:99975"
     misc_feature    1409896..1410900
                     /locus_tag="Smed_4899"
                     /note="Glycosyltransferase [Cell envelope biogenesis,
                     outer membrane]; Region: RfaG; COG0438"
                     /db_xref="CDD:223515"
     misc_feature    order(1409938..1409940,1410412..1410420,1410598..1410600,
                     1410667..1410669)
                     /locus_tag="Smed_4899"
                     /note="putative ADP-binding pocket [chemical binding];
                     other site"
                     /db_xref="CDD:99975"
     gene            1411022..1411648
                     /locus_tag="Smed_4900"
                     /db_xref="GeneID:5318238"
     CDS             1411022..1411648
                     /locus_tag="Smed_4900"
                     /note="PFAM: Exopolysaccharide synthesis ExoD;
                     KEGG: sme:SMb21582 putative ExoD-like membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide synthesis ExoD"
                     /protein_id="YP_001313617.1"
                     /db_xref="GI:150377021"
                     /db_xref="InterPro:IPR010331"
                     /db_xref="GeneID:5318238"
                     /translation="MKARLLDTVRYGDRRDRAPSIGALADALVAGAARAEPLSLGELL
                     LLIGDRSFGAVLVLAAGANLSPAGLIPAASTLLAVVVVFVSLQLVAGLRHIWIPHSLR
                     RKKLSPRLVEGTGRTMKTWSRWLDPWLTRGLRPLSEPPFDRLAGLICVLLAVPVPLLE
                     FVPFVTNVPMTIVAVFGLGLLVRNGFLLALGFAASLAAAYFAYRLLTL"
     misc_feature    1411160..1411576
                     /locus_tag="Smed_4900"
                     /note="Exopolysaccharide synthesis, ExoD; Region: ExoD;
                     cl01617"
                     /db_xref="CDD:242607"
     gene            1411813..1412025
                     /locus_tag="Smed_4901"
                     /db_xref="GeneID:5318239"
     CDS             1411813..1412025
                     /locus_tag="Smed_4901"
                     /note="KEGG: sme:SMb21583 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313618.1"
                     /db_xref="GI:150377022"
                     /db_xref="GeneID:5318239"
                     /translation="MERTNARKLATEYLRLGGHRRVVIDDNQTSVRNWENEPAEADAF
                     WRRNIETLPPEMQREVELLLPTINRA"
     gene            1412054..1412737
                     /locus_tag="Smed_4902"
                     /pseudo
                     /db_xref="GeneID:5317879"
     gene            complement(1412815..1414074)
                     /locus_tag="Smed_4903"
                     /db_xref="GeneID:5317880"
     CDS             complement(1412815..1414074)
                     /locus_tag="Smed_4903"
                     /note="PFAM: RNA-directed DNA polymerase (Reverse
                     transcriptase); Group II intron maturase-specific domain
                     protein;
                     KEGG: sme:SMb21045 putative reverse transcriptasematurase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="YP_001313619.1"
                     /db_xref="GI:150377023"
                     /db_xref="InterPro:IPR000123"
                     /db_xref="InterPro:IPR000477"
                     /db_xref="InterPro:IPR013597"
                     /db_xref="GeneID:5317880"
                     /translation="MTSIDTTDKPFRIEKRQVYEAYKAVKANHGAAGVDGETLEMFEK
                     DLARNLYKIWNRMSSGTYFPPPVRAVSIPKKTGGERVLGVPTVSDRIAQMVVKQMIEP
                     DLDSLFLPDSYGYRPGKSALDAVGVTRQRCWKYDWVLEFDIKGLFDNLPHDLLLKAVR
                     KHVKCNWALLYIERWLVAPMEKNGAVIERTRGTPQGGVVSPILSNLFLHYAFDVWMTR
                     THPDLPWCRYADDGLVHCRTEQEAQALKAALQARLAECGLQMHPIKTQIVYCKDNRRR
                     KRYPTVKFDFLGYQFRPRQVATAQQDEFFCGYTPAASPTALKSMRATIKSLNIPRQTP
                     GTLAEIAKQINPLLRGWIAYYGRFSRSALFSLADYINRKLKAWIMRKYKRFRFHKTRA
                     SQFLRQLARDNRGLFVHWQAFGTNLFA"
     misc_feature    complement(1413202..1413873)
                     /locus_tag="Smed_4903"
                     /note="RT_G2_intron: Reverse transcriptases (RTs) with
                     group II intron origin. RT transcribes DNA using RNA as
                     template. Proteins in this subfamily are found in
                     bacterial and mitochondrial group II introns. Their most
                     probable ancestor was a retrotransposable...; Region:
                     RT_G2_intron; cd01651"
                     /db_xref="CDD:238828"
     misc_feature    complement(1413202..1413861)
                     /locus_tag="Smed_4903"
                     /note="Reverse transcriptase (RNA-dependent DNA
                     polymerase); Region: RVT_1; pfam00078"
                     /db_xref="CDD:215698"
     misc_feature    complement(order(1413211..1413216,1413382..1413387,
                     1413391..1413393,1413487..1413492,1413634..1413651))
                     /locus_tag="Smed_4903"
                     /note="putative active site [active]"
                     /db_xref="CDD:238828"
     misc_feature    complement(order(1413385..1413387,1413490..1413492,
                     1413634..1413651))
                     /locus_tag="Smed_4903"
                     /note="putative NTP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238828"
     misc_feature    complement(1413487..1413489)
                     /locus_tag="Smed_4903"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238828"
     misc_feature    complement(1412890..1413126)
                     /locus_tag="Smed_4903"
                     /note="Group II intron, maturase-specific domain; Region:
                     GIIM; pfam08388"
                     /db_xref="CDD:219816"
     gene            1414207..1414527
                     /locus_tag="Smed_4904"
                     /db_xref="GeneID:5317881"
     CDS             1414207..1414527
                     /locus_tag="Smed_4904"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313620.1"
                     /db_xref="GI:150377024"
                     /db_xref="GeneID:5317881"
                     /translation="MLRLGFSLGIRSLVPAVPRESLCPTHAPSTPVATRPVIRRLAGL
                     SQDDETVLVSTTLEFLNDASSEGSLSFVFRTRTCSDLVRTFHPTLTTTTLYRSSSDWF
                     ETRS"
     gene            1414605..1414793
                     /locus_tag="Smed_4905"
                     /db_xref="GeneID:5317882"
     CDS             1414605..1414793
                     /locus_tag="Smed_4905"
                     /note="KEGG: sme:SMb21584 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313621.1"
                     /db_xref="GI:150377025"
                     /db_xref="GeneID:5317882"
                     /translation="MPLQHTFIHEHFPETGCAIAVEFKKFFMEEWTGEPRPEALVALR
                     RMLAATLPVLVEALKAER"
     gene            1414790..1416673
                     /locus_tag="Smed_4906"
                     /db_xref="GeneID:5317883"
     CDS             1414790..1416673
                     /locus_tag="Smed_4906"
                     /note="PFAM: protein of unknown function DUF1704;
                     KEGG: sme:SMb21585 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313622.1"
                     /db_xref="GI:150377026"
                     /db_xref="InterPro:IPR012548"
                     /db_xref="InterPro:IPR012656"
                     /db_xref="GeneID:5317883"
                     /translation="MKLARASIQAEANHPDWLAEALAAIHAGKAVRQEFAGGGRLHID
                     RALPFLCVHLAGDAAPVAREIVRANASHLLAPDAATAKPLVTAIGELLERRFGAFMVL
                     DIGELAKDELLTDKSPFLPPFKVDVMADRRRNIQPAAKAFIDAVEATLAQFRTPRVER
                     HEWQAYREEEALDLPFPSMRVRFAPIYRQPDSGQVFPELRERLIATIFDAALHAFAAF
                     AKATGSLEFPSHRALGRRAFIDAVERTDRSIDEVASSFDFLLAVTPINAEAAWSEFAA
                     GGFARSPRFLYRPLVIEIENAKKMLFSIPFDHLEDPVLYQLYREKQQELDLQLSMLSA
                     RETKKFVEYSRALYGPVEPNLLRAAENILDQSRNLAGYPAAPAAELRADSHVIEKRAR
                     QMIDAYAQRYAGFEALVEIRDDLPAGLLVSGKRLFIARSTSMAPDRVEPILSHEIGVH
                     LLTYFNGSAQGLRLFRSGLAGYEGMQEGLAVFSEYLSGGMTGERLRLLAARVTACAAM
                     LEGASLPEVYHRLVDDHGFREADAFNVVVRIYRGGGLAKDAIYLRGLLQLLDHLAGGG
                     ALEPFWMGKIAASHFDVMQELHARGLLRGPSVLPLFLDSPEASSRLARTCERMAPLDL
                     LQQ"
     misc_feature    1415345..1416667
                     /locus_tag="Smed_4906"
                     /note="Domain of unknown function (DUF1704); Region:
                     DUF1704; cl06858"
                     /db_xref="CDD:244535"
     gene            1416685..1417731
                     /locus_tag="Smed_4907"
                     /db_xref="GeneID:5317884"
     CDS             1416685..1417731
                     /locus_tag="Smed_4907"
                     /EC_number="6.3.2.3"
                     /note="The second step in the glutathione biosynthesis
                     pathway, where it synthesizes ATP +
                     gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate +
                     glutathione"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthetase"
                     /protein_id="YP_001313623.1"
                     /db_xref="GI:150377027"
                     /db_xref="InterPro:IPR001199"
                     /db_xref="InterPro:IPR004218"
                     /db_xref="InterPro:IPR011761"
                     /db_xref="InterPro:IPR013651"
                     /db_xref="GeneID:5317884"
                     /translation="MRMAFFVNSIEGEASYYTTTWLALAALARGHEVCYVTPGDFVLR
                     QDDSLLIRATTLRGTKPKKPETFLAALQGKQAEIVTLDLREVQVLFLRNDPSEDADTR
                     PWAVYVGTNFGRLAAARGVIVVNDPDGLSLAQNKLYFQEFPEIIRPTSLISRSIEEIR
                     SFLADHPGGAILKPLQGSGGKNVFKIDSKDETNLNQIFEVASDGGYLIAQTYIPDAVA
                     GDIRLFLLNGKPLERNGVYAAFRRVPAKGDVRSNMHASGTAEAATITPEILEIAERLR
                     PKLIEDGMFLVGLDIVGDKVLEANVFTPGGLPEIAAIHGVDFSEDIIIALENKLRIQE
                     LYRGKVQNRTLAIL"
     misc_feature    1416703..1417713
                     /locus_tag="Smed_4907"
                     /note="glutathione synthetase; Provisional; Region:
                     PRK12458"
                     /db_xref="CDD:183536"
     misc_feature    <1416769..1417074
                     /locus_tag="Smed_4907"
                     /note="Prokaryotic glutathione synthetase, N-terminal
                     domain; Region: GSH-S_N; pfam02951"
                     /db_xref="CDD:190485"
     misc_feature    1417087..1417626
                     /locus_tag="Smed_4907"
                     /note="Prokaryotic glutathione synthetase, ATP-grasp
                     domain; Region: GSH-S_ATP; pfam02955"
                     /db_xref="CDD:202486"
     gene            1417869..1418831
                     /locus_tag="Smed_4908"
                     /db_xref="GeneID:5317885"
     CDS             1417869..1418831
                     /locus_tag="Smed_4908"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     KEGG: sme:SMb21587 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313624.1"
                     /db_xref="GI:150377028"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5317885"
                     /translation="MKLMKALASATILAACTFGSASAADLVVGFSQIGSESGWRAAET
                     TLTKQQAEERGIDLKFADAQQKQENQIKAIRSFIAQGVNAILLAPVVATGWDEVLEEA
                     KDAEIPVILLDRTVDASKDLYLTAVTSDLVHEGSVAGKWLVDTVAGKPCNVVELQGTT
                     GSSPAIDRKKGFEQALSGNDNLKIVRSQTGDFTRTKGKEVMESFLKAEDGGKNICALY
                     AHNDDMAVGAIQAIKEAGLKPGKDILVVSIDAVPDIFQAMAAGEANATVELTPNMAGP
                     AFDALAAYLKDGKEPPKWIQTESKLYTQADDPMKVYEEKKGLGY"
     misc_feature    1417869..1418825
                     /locus_tag="Smed_4908"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     RbsB; COG1879"
                     /db_xref="CDD:224791"
     sig_peptide     1417869..1417940
                     /locus_tag="Smed_4908"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.987 at
                     residue 24"
     misc_feature    1417947..1418774
                     /locus_tag="Smed_4908"
                     /note="Periplasmic binding domain of ABC-type YtfQ-like
                     transport systems; Region: PBP1_YtfQ_like; cd06309"
                     /db_xref="CDD:107304"
     misc_feature    order(1417983..1417985,1418205..1418207,1418370..1418372,
                     1418613..1418615,1418673..1418675)
                     /locus_tag="Smed_4908"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107304"
     gene            1418920..1420437
                     /locus_tag="Smed_4909"
                     /db_xref="GeneID:5317886"
     CDS             1418920..1420437
                     /locus_tag="Smed_4909"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21588 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313625.1"
                     /db_xref="GI:150377029"
                     /db_xref="InterPro:IPR000897"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5317886"
                     /translation="MQTNSDNILSAVRIEKGFPGTKALDKVDLHLRRGEVHALLGENG
                     AGKSTLIKCLTGAYRRDGGSILLDGAEVDPRDTFEAQRLGIGTVYQEVNLLPNLTVAE
                     NLYLGRQPRRFGMVDTRSMNRKARELLAEYELDIDVTRDLASYSVAIQQVVAIARAVD
                     LSGKVLILDEPTASLDAHEVEMLFRIVRRLKKRGLGIIFITHFLEQVYAISDRITVLR
                     NGQLVGTREARELDRRELIAMMIGRELATEIQSVHPDAVEGEPRYTFRNYGRRGKIDP
                     FDLDVRAGEVVGMAGLLGSGRTETAEILFGAHRADSGTAKVDGRTVDLSSPRAAIRQK
                     FGFCPEDRKTAGIVGDLSVRENIVLALQARRGWTRPIPRVEQNRLADLYIRALDIRTA
                     DREKPIKLLSGGNQQKAILARWLATEPDLLILDEPTRGIDVGAHAEIIRLIESLREKG
                     MSLIVISSEIEELVAYSTRVVVLRDHAHVAELNGAQLTAHRIVEAIAATNGRKAS"
     misc_feature    1418920..1420413
                     /locus_tag="Smed_4909"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     misc_feature    1418944..1419594
                     /locus_tag="Smed_4909"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    1419040..1419063
                     /locus_tag="Smed_4909"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(1419049..1419054,1419058..1419066,1419187..1419189,
                     1419424..1419429,1419523..1419525)
                     /locus_tag="Smed_4909"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    1419178..1419189
                     /locus_tag="Smed_4909"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    order(1419211..1419225,1419241..1419246,1419262..1419270)
                     /locus_tag="Smed_4909"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    1419412..1419429
                     /locus_tag="Smed_4909"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    1419436..1419447
                     /locus_tag="Smed_4909"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    1419511..1419531
                     /locus_tag="Smed_4909"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     misc_feature    1419694..1420344
                     /locus_tag="Smed_4909"
                     /note="Second domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_II; cd03215"
                     /db_xref="CDD:213182"
     gene            1420437..1421459
                     /locus_tag="Smed_4910"
                     /db_xref="GeneID:5317887"
     CDS             1420437..1421459
                     /locus_tag="Smed_4910"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb21589 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001313626.1"
                     /db_xref="GI:150377030"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5317887"
                     /translation="MPIMRTYAGRLLPQCIALVIIVIAISIVFPGFLNLQIQNGRLYG
                     SLIDILNRGAPVVLLAIGMTVVIATKGIDLSVGAVMAICGAVAASLITSGHSLAETLL
                     ATLAIGILCGIWNGVLVAFLDIQPIIATLVLMVAGRGIAQLITEGTILTFNEPGLIFI
                     GSGSFIGLPMPIVIWLVFGLLVAVLVRRTALGMLIEAIGINRQASTLSGVLTPVLLVA
                     AYVLSGLCAAIAGIIAAADIRGADANNAGLWLELDAILAVVVGGTSLLGGRFSIAASV
                     LGAIIIQAINTGILLSGFPPEFNLIIKAAIIIFILVLQSPRFRTAFSFLSIPGAAGKP
                     TEREAK"
     misc_feature    1420569..1421336
                     /locus_tag="Smed_4910"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    1420596..1421330
                     /locus_tag="Smed_4910"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    1421043..1421099
                     /locus_tag="Smed_4910"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            1421456..1422424
                     /locus_tag="Smed_4911"
                     /db_xref="GeneID:5317888"
     CDS             1421456..1422424
                     /locus_tag="Smed_4911"
                     /EC_number="3.6.3.17"
                     /note="membrane component of a putative sugar ABC
                     transporter system"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane ABC transporter permease YjfF"
                     /protein_id="YP_001313627.1"
                     /db_xref="GI:150377031"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5317888"
                     /translation="MKQKYLPLTATILIFVLSYALCAAQYPNILSTRVIGNLLTDNAF
                     LGIAAVGMTFVILSGGIDLSIGAVIAFAGVFLAVVLEHGSMHPLVAFALLLTITTLFG
                     ALMGAIIHYLEMPAFIVTLAGMFLARGMAFVLSIDSIPIKHPFYGTLKSLYYKLPGGG
                     RITLIGGLMLLVFAIGILIAHRTRFGTNIYALGGGTATAKLMGVPVAATTVRIYALSG
                     LLAGLSGIVFSLYTSAGYSLAAVGVELDAITAVVIGGTLLTGGSGFVAGTLVGILIQG
                     LIQTYITFDGTLSSWWTKILIGLLLFAFILLQKGIIHLSRPERQRA"
     sig_peptide     1421456..1421527
                     /locus_tag="Smed_4911"
                     /product="inner membrane ABC transporter permease protein
                     YjfF"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.992) with cleavage site probability 0.815 at
                     residue 24"
     misc_feature    1421558..1422337
                     /locus_tag="Smed_4911"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    1421579..1422328
                     /locus_tag="Smed_4911"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    1422044..1422100
                     /locus_tag="Smed_4911"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            1422442..1423176
                     /locus_tag="Smed_4912"
                     /db_xref="GeneID:5317889"
     CDS             1422442..1423176
                     /locus_tag="Smed_4912"
                     /note="PFAM: regulatory protein GntR HTH; GntR domain
                     protein;
                     KEGG: sme:SMb21591 putative transcriptional regulator,
                     GntR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="YP_001313628.1"
                     /db_xref="GI:150377032"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="GeneID:5317889"
                     /translation="MPGAFGTQRGKRTSHRLVVDELGQAVVGGEFSVGDTLPGDTDLA
                     ARFNVSRTVLREAMKTLAAKGLVVPRARIGTRVLPKAHWNLFDSDVLTWHFGAGVDEK
                     FLRHVSEVRLALEPYAAALAARRASDADIARMMRLAVAMGDAGHSPHTLAQADLEFHL
                     RLLEASLNPFMRTVGSLIEAALIGVFQLTSPTADETEIDRVAIAHIRIVEEIRRRNED
                     GARRAMEHVIRVGQERLILNLKERQG"
     misc_feature    1422466..1423170
                     /locus_tag="Smed_4912"
                     /note="Transcriptional regulators [Transcription]; Region:
                     FadR; COG2186"
                     /db_xref="CDD:225097"
     misc_feature    1422484..1422672
                     /locus_tag="Smed_4912"
                     /note="Winged helix-turn-helix (WHTH) DNA-binding domain
                     of the GntR family of transcriptional regulators; Region:
                     WHTH_GntR; cd07377"
                     /db_xref="CDD:153418"
     misc_feature    order(1422484..1422486,1422553..1422555,1422559..1422564,
                     1422586..1422600,1422604..1422609,1422616..1422618,
                     1422646..1422651,1422655..1422666)
                     /locus_tag="Smed_4912"
                     /note="DNA-binding site [nucleotide binding]; DNA binding
                     site"
                     /db_xref="CDD:153418"
     gene            complement(1423315..1424466)
                     /locus_tag="Smed_4913"
                     /db_xref="GeneID:5319125"
     CDS             complement(1423315..1424466)
                     /locus_tag="Smed_4913"
                     /note="PFAM: ABC transporter related; TOBE domain protein;
                     Transport-associated OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21592 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313629.1"
                     /db_xref="GI:150377033"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR005116"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5319125"
                     /translation="MTLQIELNGVNKFYGSYHALKNIDLAIEEGTFVALVGPSGCGKS
                     TLLRSLAGLEKISAGEMKIAGARMNDVPPRKRDVAMVFQSYALYPHMTVEENLTYSLR
                     IRGVKKAEALRAAAEVATTTGLSHLMKRYPRELSGGQRQRVAMSRAIIRHPKAFLFDE
                     PLSNLDAALRVHMRKEIRALHDRLGATSVYVTHDQIEAMTMADHVVVMRDGIIEQQGR
                     PLDLYDRPANRFVAGFIGSPAMNFIPAVVEQDGRHLALDLGATQARLALVETVPAGAS
                     VTVGIRPEHIRIVGAGQGALDIPVGVVESTGSATYITSATQPELMVVETGRSAAVGGE
                     LIGLAIDPAQLHLFDAETGNRLGIGRAHESEKFAPRAAPHPAAATFSPS"
     misc_feature    complement(1423414..1424457)
                     /locus_tag="Smed_4913"
                     /note="ABC-type sugar transport systems, ATPase components
                     [Carbohydrate transport and metabolism]; Region: MalK;
                     COG3839"
                     /db_xref="CDD:226359"
     misc_feature    complement(1423816..1424454)
                     /locus_tag="Smed_4913"
                     /note="ATP-binding cassette transporter nucleotide-binding
                     domain; Region: ABC_ATPase; cl17201"
                     /db_xref="CDD:247755"
     misc_feature    complement(1424335..1424358)
                     /locus_tag="Smed_4913"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(order(1423888..1423890,1423987..1423992,
                     1424218..1424220,1424332..1424340,1424344..1424349))
                     /locus_tag="Smed_4913"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(1424218..1424229)
                     /locus_tag="Smed_4913"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(1424035..1424064)
                     /locus_tag="Smed_4913"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(1423987..1424004)
                     /locus_tag="Smed_4913"
                     /note="Walker B; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(1423969..1423980)
                     /locus_tag="Smed_4913"
                     /note="D-loop; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(1423882..1423902)
                     /locus_tag="Smed_4913"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213179"
     misc_feature    complement(1423423..1423632)
                     /locus_tag="Smed_4913"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            complement(1424463..1425290)
                     /locus_tag="Smed_4914"
                     /db_xref="GeneID:5319126"
     CDS             complement(1424463..1425290)
                     /locus_tag="Smed_4914"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21593 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313630.1"
                     /db_xref="GI:150377034"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319126"
                     /translation="MSDAFRNRLMLAVALVLAAIYLFPLYWMYITALKTGSAMFATPP
                     KFWPSEPQWSIYAHVWESRNMGRYLWNSLVIAFGSVALIAVLGVGCAYVLARYRNVWV
                     DIGLFLILMLQVLPASLMVTPIFVGFSQVGLLDTPRLAVILAIAAKSMPFFVVLVRAT
                     FMSVPMELEEAALVDGNSRIGAFFNIVLPLARNGILVSAILIFMQAFGEFVYSKSMIQ
                     AVELQPASVGLNTFMGPNTNEWNNIMAYATIYVTPILAAFILLQRRIVSGLTSGALK"
     misc_feature    complement(1424466..1425233)
                     /locus_tag="Smed_4914"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    complement(<1424658..1425086)
                     /locus_tag="Smed_4914"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1424658..1424669,1424688..1424690,
                     1424697..1424702,1424742..1424744,1424793..1424795,
                     1424802..1424807,1424817..1424819,1424823..1424828,
                     1424835..1424837,1424841..1424843,1424847..1424852,
                     1424916..1424918,1424922..1424927,1424934..1424963,
                     1424967..1424978,1425006..1425008,1425021..1425026,
                     1425033..1425038))
                     /locus_tag="Smed_4914"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1424658..1424669,1424916..1424960))
                     /locus_tag="Smed_4914"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1424721..1424723,1424733..1424738,
                     1424754..1424792))
                     /locus_tag="Smed_4914"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1425287..1426189)
                     /locus_tag="Smed_4915"
                     /db_xref="GeneID:5319127"
     CDS             complement(1425287..1426189)
                     /locus_tag="Smed_4915"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21594 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313631.1"
                     /db_xref="GI:150377035"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319127"
                     /translation="MKRILSSITDGRGFDVGLVSLPLAFLFVLSGLPLVYNVVMSFQE
                     VDMFSLGSFSRPFVGFKNYIDLFGQPETWPILLNTAIFVTASIAGQFLIGFGLALFFW
                     VSFPGASWLRGLFLVSWVMPGLVVGAIWNWILSGDFGVLNFLLRETGVISGNIFWRSD
                     PSHSLWAVIIANIWLGTSFNMILLSVGLSGIPKDLYEAAELDGANAFQRFWTITLPMM
                     RSTIGAIVALGLIFTLQQFDLFAAITSGGPNNTSNVTQYWAWDLSFRQYDFAKGATIS
                     VIMIVFVMFASVVYVRSTRHEVRG"
     misc_feature    complement(1425305..1426165)
                     /locus_tag="Smed_4915"
                     /note="ABC-type spermidine/putrescine transport system,
                     permease component II [Amino acid transport and
                     metabolism]; Region: PotC; COG1177"
                     /db_xref="CDD:224098"
     misc_feature    complement(1425341..1425964)
                     /locus_tag="Smed_4915"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1425341..1425343,1425350..1425355,
                     1425362..1425367,1425371..1425376,1425383..1425388,
                     1425416..1425421,1425464..1425469,1425476..1425487,
                     1425506..1425508,1425515..1425520,1425560..1425562,
                     1425611..1425613,1425620..1425625,1425635..1425637,
                     1425641..1425646,1425653..1425655,1425659..1425661,
                     1425668..1425673,1425746..1425748,1425803..1425808,
                     1425815..1425844,1425848..1425859,1425899..1425904,
                     1425911..1425916))
                     /locus_tag="Smed_4915"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1425470..1425487,1425746..1425748,
                     1425800..1425841))
                     /locus_tag="Smed_4915"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1425386..1425388,1425416..1425418,
                     1425425..1425427,1425467..1425469,1425686..1425688,
                     1425746..1425748))
                     /locus_tag="Smed_4915"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1425539..1425541,1425551..1425556,
                     1425572..1425610))
                     /locus_tag="Smed_4915"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1426382..1427614)
                     /locus_tag="Smed_4916"
                     /db_xref="GeneID:5319128"
     CDS             complement(1426382..1427614)
                     /locus_tag="Smed_4916"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb21595 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313632.1"
                     /db_xref="GI:150377036"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5319128"
                     /translation="MGIRKYAMLGAFALASVSLSTFGASAEDVTIRVWSLDRDIQPAP
                     NLIKDFNELNSGIKVEYRQIQFDDVVSEAMRAYSTGQAPDIIAVDNPEHALFASRGAF
                     LDLSDMIAKSSVVKPENYFKGPLASVTWDGKYYGIPKATNTIALYYNKDMFKAKGLDP
                     NKPPQTWDELVEAARKLSDPAQNVYGITFSAKANEEGTFQFLPWAQMAGGGYDNINSE
                     GAVKALDVWKTIIDEKLASPDTLTRSQWDATGTFNSGNAAMAISGPWELDRMLEEAKF
                     DWGVALMPVPQAGAERSSAMGDFNWAIFANTEHPEEAFKVLEYFVSQDDRMFKDFGQL
                     PPRSDIAIPATGEPKKDAALQVFVEQLKYAKPRGPHPAWPKISKAIQDAIQAALTGQM
                     SSKEALDQAAEKIKAVLG"
     misc_feature    complement(1426388..1427614)
                     /locus_tag="Smed_4916"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     sig_peptide     complement(1427534..1427614)
                     /locus_tag="Smed_4916"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.969 at
                     residue 27"
     misc_feature    complement(1426634..1427500)
                     /locus_tag="Smed_4916"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     gene            complement(1427677..1428579)
                     /locus_tag="Smed_4917"
                     /db_xref="GeneID:5319129"
     CDS             complement(1427677..1428579)
                     /locus_tag="Smed_4917"
                     /note="PFAM: Xylose isomerase domain protein TIM barrel;
                     KEGG: sme:SMb21596 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase domain-containing protein"
                     /protein_id="YP_001313633.1"
                     /db_xref="GI:150377037"
                     /db_xref="InterPro:IPR012307"
                     /db_xref="GeneID:5319129"
                     /translation="MSNPAKSIRIGTMVSATKGEAAKRIGEIADLGFESFEPFFWQTT
                     NGQDLAELGKRCRDAIGDRDITISTLGMFGNPLEETDIDLQTLQGWKDCIDNAHHFGA
                     TCVAGFTGRIRNRPLTDSLPRYRKVWSELAQRAADKGVKIAFENCAMDGNWATGDWNI
                     AHNPDAWELIFNETPDDNIGIEWEPCHQMVYLIDPLPQIRKWAHKIFHVHGKDATIRW
                     DVIREHGIFGKEKFVFMRTPGFGDSNWTDIISELRLAGWSGSIDIEGWHDPVYRDALE
                     MTGQVHALNYLKGSRGGDFVADRA"
     misc_feature    complement(1427713..1428501)
                     /locus_tag="Smed_4917"
                     /note="Sugar phosphate isomerases/epimerases [Carbohydrate
                     transport and metabolism]; Region: IolE; COG1082"
                     /db_xref="CDD:224007"
     gene            complement(1428592..1429584)
                     /locus_tag="Smed_4918"
                     /db_xref="GeneID:5319130"
     CDS             complement(1428592..1429584)
                     /locus_tag="Smed_4918"
                     /note="PFAM: oxidoreductase domain protein; Oxidoreductase
                     domain;
                     KEGG: sme:SMb21597 putative exported oxidoreductase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain-containing protein"
                     /protein_id="YP_001313634.1"
                     /db_xref="GI:150377038"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="GeneID:5319130"
                     /translation="MARGWLKAIAADRELQSIIRVVGLVDVNPEAARALAAEFEIEDA
                     VIGSDLDAVLTETAPDILFDIVIPAARRDVVATALRHGCHVLSEKPMAASLEAARELI
                     ELAGNAGRIHAIVQNRRFIAGIRRIRRFIESGAIGDLTAIHCDFFIGAHFGGFREEME
                     HVLLLDMAIHTFDAARFIADKTPLAVYCHEENPRGSWYTHGAAATAIFELADDVTFTY
                     RGSWCAEGANTSWESEWRILGTEGTLLWDGAEALSANRVAGSEGFFRPLAPIEIPDPA
                     DPRETQGHASVIADFVAAVRTGTKPETVGDDNINSLAMVFAAIESARTRQRVTI"
     misc_feature    complement(1428595..1429560)
                     /locus_tag="Smed_4918"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:223745"
     misc_feature    complement(1429252..1429560)
                     /locus_tag="Smed_4918"
                     /note="Oxidoreductase family, NAD-binding Rossmann fold;
                     Region: GFO_IDH_MocA; pfam01408"
                     /db_xref="CDD:201778"
     gene            1429854..1430903
                     /locus_tag="Smed_4919"
                     /db_xref="GeneID:5319131"
     CDS             1429854..1430903
                     /locus_tag="Smed_4919"
                     /note="PFAM: periplasmic binding protein/LacI
                     transcriptional regulator;
                     SMART: regulatory protein LacI;
                     KEGG: sme:SMb21598 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein/LacI transcriptional
                     regulator"
                     /protein_id="YP_001313635.1"
                     /db_xref="GI:150377039"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /db_xref="GeneID:5319131"
                     /translation="MKGIRRLAQHLDISIGTVSRALNGRPDVNEETRRRVLEAAEKLG
                     YVPNQSGRSLRQGTTNIIGFMMQTGTEITGQGDTFFMSVFDGVQAVFARHKLDLVALL
                     CSSEEDQSDYLRRVVARGFADGLILSATQRHDPRIEYLAERNIPFITLGRSLTDVGRP
                     WLDLDFEGMAQIAIDRLVARGHRRIAVTRPHDDANLGYIFVDRCREALAAHGLTLEEE
                     LIFRSTPNETGGYQIARELLKLEDRPTAALLVNETIAIGFYQGLSEAGVRPGRDIAVI
                     GRYSPHAHFLSPPLTCFRLSLRDLGIALAETLLSTMPTFQEHYPQALTNAVWPMELIE
                     GESDGFRVNGDESRG"
     misc_feature    1429863..1430870
                     /locus_tag="Smed_4919"
                     /note="Transcriptional regulators [Transcription]; Region:
                     PurR; COG1609"
                     /db_xref="CDD:224525"
     misc_feature    1429866..1430021
                     /locus_tag="Smed_4919"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(1429866..1429868,1429890..1429904,1429908..1429913,
                     1429920..1429922,1429935..1429940,1429947..1429949,
                     1429986..1429988,1429995..1429997,1430004..1430009,
                     1430013..1430018)
                     /locus_tag="Smed_4919"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    1429986..1430015
                     /locus_tag="Smed_4919"
                     /note="domain linker motif; other site"
                     /db_xref="CDD:143331"
     misc_feature    1430037..1430852
                     /locus_tag="Smed_4919"
                     /note="Ligand-binding domain of DNA transcription
                     repressors specific for raffinose (RafR) and
                     alpha-glucosides (AglR) which are members of the LacI-GalR
                     family of bacterial transcription regulators; Region:
                     PBP1_AglR_RafR_like; cd06271"
                     /db_xref="CDD:107266"
     misc_feature    order(1430088..1430090,1430100..1430102,1430298..1430303,
                     1430334..1430345,1430451..1430453,1430604..1430606,
                     1430688..1430690)
                     /locus_tag="Smed_4919"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107266"
     gene            1431105..1431404
                     /locus_tag="Smed_4920"
                     /db_xref="GeneID:5319132"
     CDS             1431105..1431404
                     /locus_tag="Smed_4920"
                     /note="KEGG: sme:SMb21599 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313636.1"
                     /db_xref="GI:150377040"
                     /db_xref="GeneID:5319132"
                     /translation="MRGFIFLLAGLSATTALAHDAPNGWQYPSACCSTMDCRKVAQND
                     ISERPQGYIVRATGEVLPYADSRVRMSPDGEYHWCSASGKAYGKTICLFVPPRAY"
     sig_peptide     1431105..1431161
                     /locus_tag="Smed_4920"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 19"
     gene            complement(1431481..1432641)
                     /gene="ampC"
                     /locus_tag="Smed_4921"
                     /db_xref="GeneID:5319133"
     CDS             complement(1431481..1432641)
                     /gene="ampC"
                     /locus_tag="Smed_4921"
                     /EC_number="3.5.2.6"
                     /note="PFAM: beta-lactamase;
                     KEGG: sme:SMb21600 putative exported beta-lactamase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase"
                     /protein_id="YP_001313637.1"
                     /db_xref="GI:150377041"
                     /db_xref="InterPro:IPR001466"
                     /db_xref="InterPro:IPR001586"
                     /db_xref="GeneID:5319133"
                     /translation="MAAIALLSCGGGAHAAGQGDEGQLARVVDEAIRPLMEENGVPGM
                     AVAVTVSGKRYVFNYGLASKEGGKKVTDDTMFEIGSISKTFTATLAAYAEARGNLSLA
                     EPASKYLPALSGTPFDEIRLLDLGTYAAGGLPLQFPDAVSGEESMIEYFKSWRPTYAA
                     GTYRLYSNPSIGLFGYLAAKSMGAPFADLMEETVIRGLALKSTFISVPDDRMDDYAYG
                     YSKAGKPIRVTRGVFDSQAYGVKTTAADLLRFVEASIDDTGLEEMLRHAITATHTGYF
                     KVGPMTQGLGWEMYAYPPKLDDLLTGNSARMALEPSKVDKIVPPSAPRKDIWINKTGS
                     TNGFGAYTAFVPAERIGIVMLANRNYPIAARVKAAYRILSTLDDKLGSADPR"
     misc_feature    complement(1431520..1432641)
                     /gene="ampC"
                     /locus_tag="Smed_4921"
                     /note="Beta-lactamase class C and other penicillin binding
                     proteins [Defense mechanisms]; Region: AmpC; COG1680"
                     /db_xref="CDD:224594"
     sig_peptide     complement(1432594..1432641)
                     /gene="ampC"
                     /locus_tag="Smed_4921"
                     /product="beta-lactamase"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.952) with cleavage site probability 0.907 at
                     residue 16"
     misc_feature    complement(1431511..1432638)
                     /gene="ampC"
                     /locus_tag="Smed_4921"
                     /note="beta-lactamase/D-alanine carboxypeptidase;
                     Provisional; Region: ampC; PRK11289"
                     /db_xref="CDD:236894"
     gene            complement(1432823..1432987)
                     /locus_tag="Smed_4922"
                     /pseudo
                     /db_xref="GeneID:5319134"
     gene            1433129..1434250
                     /locus_tag="Smed_4923"
                     /db_xref="GeneID:5319135"
     CDS             1433129..1434250
                     /locus_tag="Smed_4923"
                     /note="PFAM: CBS domain containing protein; peptidase M50;
                     KEGG: sme:SMb20925 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50"
                     /protein_id="YP_001313638.1"
                     /db_xref="GI:150377042"
                     /db_xref="InterPro:IPR000644"
                     /db_xref="InterPro:IPR008915"
                     /db_xref="GeneID:5319135"
                     /translation="MAWSFRIGTIAGTAIRVHVTFALLLIWIWLTHYRIGGTVAAMEG
                     IAFIVAVFVCVVLHEFGHIAAARRFGIKTPDITLLPIGGVARLERMPEEPGQEFMIAI
                     AGPLVNVAIAGVLVAILGSYTAMGQLADVEDPQSGFLARLAGVNVFLVLFNMIPAFPM
                     DGGRVLRAALASRLSWSRATQIAATIGQGLAFVFGFAGLFYNPLLIFIAIFVYLAATA
                     EAQNAQIREVSSSVMIADVMITEFTTLDRSATIDEAIDTLLATTQREFPVVDLAGHFE
                     GLLTRDDMIRTLKEKGAATPVVAAMRRDVPTIHHRKRLEESLRLMQESHSPAVAVVDG
                     SNRLVGLMTHETIGEMMMVRAAAAGRFRFGHLRQTGSRG"
     misc_feature    1433150..1433797
                     /locus_tag="Smed_4923"
                     /note="SpoIVFB Site-2 protease (S2P), a zinc
                     metalloprotease (MEROPS family M50B), regulates
                     intramembrane proteolysis (RIP), and is involved in the
                     pro-sigmaK pathway of bacterial spore formation. In this
                     subgroup, SpoIVFB (sporulation protein, stage IV cell...;
                     Region: S2P-M50_SpoIVFB_CBS; cd06164"
                     /db_xref="CDD:100085"
     misc_feature    1433297..1433623
                     /locus_tag="Smed_4923"
                     /note="Peptidase family M50; Region: Peptidase_M50;
                     pfam02163"
                     /db_xref="CDD:216910"
     misc_feature    order(1433300..1433305,1433312..1433314,1433585..1433587,
                     1433609..1433611)
                     /locus_tag="Smed_4923"
                     /note="active site"
                     /db_xref="CDD:100085"
     misc_feature    1433585..1433596
                     /locus_tag="Smed_4923"
                     /note="putative substrate binding region [chemical
                     binding]; other site"
                     /db_xref="CDD:100085"
     misc_feature    1433828..1434169
                     /locus_tag="Smed_4923"
                     /note="FOG: CBS domain [General function prediction only];
                     Region: COG0517"
                     /db_xref="CDD:223591"
     misc_feature    1433846..1434178
                     /locus_tag="Smed_4923"
                     /note="The CBS domain, named after human CBS, is a small
                     domain originally identified in cystathionine
                     beta-synthase and is subsequently found in a wide range of
                     different proteins. CBS domains usually occur in tandem
                     repeats. They associate to form a so-called...; Region:
                     CBS_pair_26; cd04639"
                     /db_xref="CDD:240010"
     gene            1434405..1434905
                     /locus_tag="Smed_4924"
                     /db_xref="GeneID:5318240"
     CDS             1434405..1434905
                     /locus_tag="Smed_4924"
                     /note="KEGG: sme:SMb20926 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313639.1"
                     /db_xref="GI:150377043"
                     /db_xref="GeneID:5318240"
                     /translation="MLVTVEVITIVLVAIATALALAHALEWPGKLRLPKEQYLAIQAI
                     YYPGFTIGGVAEPLSLLFTAALLVLMPRGTPAFWMTVGALIGLLAMHATYWILTHPVN
                     NFWLKDTQLAKTSGRFFAVGTVRAKSVPESEDWTALRDRWERSHVVRAAFGFVSLVML
                     ATAIAL"
     sig_peptide     1434405..1434479
                     /locus_tag="Smed_4924"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.977) with cleavage site probability 0.547 at
                     residue 25"
     gene            1434970..1435413
                     /locus_tag="Smed_4925"
                     /db_xref="GeneID:5318241"
     CDS             1434970..1435413
                     /locus_tag="Smed_4925"
                     /note="PFAM: protein of unknown function DUF305;
                     KEGG: rme:Rmet_2287 protein of unknown function DUF305"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313640.1"
                     /db_xref="GI:150377044"
                     /db_xref="InterPro:IPR005183"
                     /db_xref="GeneID:5318241"
                     /translation="MSTHYLKYALNLLISLVIMYLVMFTMIDGINDFYNNPNMFYMAI
                     MMVAPMAMLMLLMMAPMYPRKRLNLALHLAFAILFIAAFTFMRMQTFVGDAQFLRSMI
                     PHHSGAILMCRESSLADPEIAALCERIIDSQKREIAEMNRILACY"
     misc_feature    1435249..>1435404
                     /locus_tag="Smed_4925"
                     /note="Domain of unknown function (DUF305); Region:
                     DUF305; cl17794"
                     /db_xref="CDD:248348"
     gene            complement(1435465..1435944)
                     /locus_tag="Smed_4926"
                     /db_xref="GeneID:5318242"
     CDS             complement(1435465..1435944)
                     /locus_tag="Smed_4926"
                     /note="KEGG: sme:SMb20927 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313641.1"
                     /db_xref="GI:150377045"
                     /db_xref="GeneID:5318242"
                     /translation="MVVYLAGLLSLLLGALSLGPSFAHVLEAPPRLFVWSPELWREAT
                     VFNGQFALFAKVGGPLDVATILATCFLSYLLSNERPAFWFALAGGGFFAGGLAAWFTL
                     VAPANAILATWQPGPIPADFEAVRLRWETGHMAVAALKVLGFGSISVALLAPRLGSG"
     sig_peptide     complement(1435873..1435944)
                     /locus_tag="Smed_4926"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.931 at
                     residue 24"
     gene            1436117..1437367
                     /locus_tag="Smed_4927"
                     /db_xref="GeneID:5318243"
     CDS             1436117..1437367
                     /locus_tag="Smed_4927"
                     /note="PFAM: peptidase S41;
                     SMART: PDZ/DHR/GLGF domain protein;
                     KEGG: sme:SMb20928 putative exported carboxyl-terminal
                     protease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="YP_001313642.1"
                     /db_xref="GI:150377046"
                     /db_xref="InterPro:IPR001478"
                     /db_xref="InterPro:IPR005151"
                     /db_xref="GeneID:5318243"
                     /translation="MHAKMPRVLLAGLLFLLVPSQGFGLDLPRSNHPVFDRVVTLVVD
                     NFHDPAALDGFGAAVRRELDDGQPLNSESPGPRVDTAIERILASLEASHTARFKQDTI
                     AYYELADIFRFAIRHDMERLFPPDGAATYAGVGMVTRMENGLRFVSDVYDGSPADKAG
                     IRVGDEVLSVDGAPYREIDSFRDRIGRTVEIRLRREADAQPFKATVAVERLRPLPTFE
                     KAIDKSVTLHEEGGRSIGYLRLWTLSSPDGLDIVARELATGRLKDADGVIVDLRGRWG
                     GGPPDAAELFVGDTPNFRLIARGSKDMLANVRWRRPVVAIIDEGSRSGLELFAYALKS
                     NGIPLVGTRTAGALLAGRAYLLPDDSILELAVSDAVIDDDVRLEGRGVEPDIIATFPL
                     PYAAGRDPQREAAFEEMRRTLAKD"
     sig_peptide     1436117..1436191
                     /locus_tag="Smed_4927"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.995) with cleavage site probability 0.853 at
                     residue 25"
     misc_feature    1436168..1437364
                     /locus_tag="Smed_4927"
                     /note="Periplasmic protease [Cell envelope biogenesis,
                     outer membrane]; Region: Prc; COG0793"
                     /db_xref="CDD:223864"
     misc_feature    1436507..1436746
                     /locus_tag="Smed_4927"
                     /note="PDZ domain of C-terminal processing-,
                     tail-specific-, and tricorn proteases, which function in
                     posttranslational protein processing, maturation, and
                     disassembly or degradation, in Bacteria, Archaea, and
                     plant chloroplasts. May be responsible for...; Region:
                     PDZ_CTP_protease; cd00988"
                     /db_xref="CDD:238488"
     misc_feature    order(1436513..1436524,1436528..1436530,1436648..1436650,
                     1436657..1436662)
                     /locus_tag="Smed_4927"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238488"
     misc_feature    <1436798..1437349
                     /locus_tag="Smed_4927"
                     /note="C-terminal processing peptidase family S41; Region:
                     Peptidase_S41; cl02526"
                     /db_xref="CDD:243070"
     misc_feature    1437083..1437085
                     /locus_tag="Smed_4927"
                     /note="Active site serine [active]"
                     /db_xref="CDD:143475"
     gene            complement(1437405..1438403)
                     /locus_tag="Smed_4928"
                     /db_xref="GeneID:5318244"
     CDS             complement(1437405..1438403)
                     /locus_tag="Smed_4928"
                     /EC_number="3.6.3.17"
                     /note="PFAM: inner-membrane translocator;
                     KEGG: sme:SMb20929 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="monosaccharide-transporting ATPase"
                     /protein_id="YP_001313643.1"
                     /db_xref="GI:150377047"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="GeneID:5318244"
                     /translation="MAITLDRAVGQRDRGWLSFLFASQAFWVLIAVILACLFLSVATD
                     SFATAKNLYNITRNFTFVAIIALGMTLVIITGGIDLSVGSVLCLSSMVLAVVMHAGYG
                     IEVGIAASIGTALLAGAFNGVMIAYLGFPPFVITLGMLSIARSLAMVASNNTVVFEFG
                     PDHDALLALGGGAWFFGIANPVLYMIVLALVTGFVLRWTKFGRYVFAIGGNEHAARLT
                     GVPVRRIKVIVYMISALAAGIAGIVQTGWLGAVTTNIGAGMELQVIAAAVIGGANLAG
                     GVGTASGALIGAALIEVIRNSLGLLGINAFWQGAFIGGAIVLAVLFDRIRNFRQSE"
     misc_feature    complement(1437441..1438253)
                     /locus_tag="Smed_4928"
                     /note="Branched-chain amino acid transport system /
                     permease component; Region: BPD_transp_2; pfam02653"
                     /db_xref="CDD:217165"
     misc_feature    complement(1437435..1438229)
                     /locus_tag="Smed_4928"
                     /note="Transmembrane subunit (TM) of Escherichia coli AraH
                     and related proteins. E. coli AraH is the TM of a
                     Periplasmic Binding Protein (PBP)-dependent ATP-Binding
                     Cassette (ABC) transporter involved in the uptake of the
                     monosaccharide arabinose. This group...; Region:
                     TM_PBP1_transp_AraH_like; cd06579"
                     /db_xref="CDD:119321"
     misc_feature    complement(1437711..1437767)
                     /locus_tag="Smed_4928"
                     /note="TM-ABC transporter signature motif; other site"
                     /db_xref="CDD:119321"
     gene            complement(1438433..1439173)
                     /locus_tag="Smed_4929"
                     /db_xref="GeneID:5318245"
     CDS             complement(1438433..1439173)
                     /locus_tag="Smed_4929"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20930 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313644.1"
                     /db_xref="GI:150377048"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318245"
                     /translation="MAVLELVNISKHFGAIQAVTDVSLSLNRGEVVGLMGDNGAGKST
                     LVKMIAGNFRPSQGTMRLDGAEIVLHRPVEARQHGIEIVYQDLALCDNLTAAANVFLG
                     REIRRGIGPLSILDYKAMYRRAGEIFKELKSETPPRDFVRQMSGGQRQAVAIARTMLS
                     DAKIVLMDEPTAAISVRQVAEVLNLIRALRDRGIAVVLISHRMPDVFTVADRVIVMRR
                     GRKVADKAIEQSSPEEVTGLITGAIEQV"
     misc_feature    complement(1438469..1439173)
                     /locus_tag="Smed_4929"
                     /note="ABC-type branched-chain amino acid transport
                     systems, ATPase component [Amino acid transport and
                     metabolism]; Region: LivG; COG0411"
                     /db_xref="CDD:223488"
     misc_feature    complement(1438502..1439164)
                     /locus_tag="Smed_4929"
                     /note="First domain of the ATP-binding cassette component
                     of monosaccharide transport system; Region:
                     ABC_Carb_Monos_I; cd03216"
                     /db_xref="CDD:213183"
     misc_feature    complement(1439045..1439068)
                     /locus_tag="Smed_4929"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(order(1438571..1438573,1438667..1438672,
                     1438745..1438747,1439042..1439050,1439054..1439059))
                     /locus_tag="Smed_4929"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1438745..1438756)
                     /locus_tag="Smed_4929"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1438715..1438744)
                     /locus_tag="Smed_4929"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1438667..1438684)
                     /locus_tag="Smed_4929"
                     /note="Walker B; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1438649..1438660)
                     /locus_tag="Smed_4929"
                     /note="D-loop; other site"
                     /db_xref="CDD:213183"
     misc_feature    complement(1438565..1438585)
                     /locus_tag="Smed_4929"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213183"
     gene            1439595..1440584
                     /locus_tag="Smed_4930"
                     /db_xref="GeneID:5318246"
     CDS             1439595..1440584
                     /locus_tag="Smed_4930"
                     /note="KEGG: sme:SMb20931 putative sugar uptake ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sugar uptake ABC transporter
                     periplasmic solute-binding protein"
                     /protein_id="YP_001313645.1"
                     /db_xref="GI:150377049"
                     /db_xref="GeneID:5318246"
                     /translation="MRKALLLAVAALALSAGTTMAQKKQLVIVVKGLDNPFFEAINQG
                     CQKWNKENPDSEYECFYTGPASTSDEAGEAQIVQDMLGKAETAAIAISPSNAKLIAQT
                     LKTSNPTVPVMTVDADLAAEDSALRKTYLGTDNYLMGYRIGEYIKKAKPDGGKICTIE
                     GNPGADNILRRAQGMRDALTGQKDLAELKGEGGWTEVAGCPVFTNDDGAKGVQAMTDI
                     LAANPDLDAFGIMGGWPLFGAPQPYRDLFRPVADKIAKNEFVIGAADTIGEEVAIARE
                     GLVTALVGQRPFEMGYKAPQVMLDLIAGKPVEDPVFTGLDECTKETADTCIQK"
     sig_peptide     1439595..1439660
                     /locus_tag="Smed_4930"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.955 at
                     residue 22"
     misc_feature    1439670..1440542
                     /locus_tag="Smed_4930"
                     /note="Periplasmic sugar-binding domain of active
                     transport systems that are members of the type I
                     periplasmic binding protein (PBP1) superfamily; Region:
                     PBP1_ABC_sugar_binding_like; cd01536"
                     /db_xref="CDD:107249"
     misc_feature    1439670..1440512
                     /locus_tag="Smed_4930"
                     /note="Periplasmic binding protein domain; Region:
                     Peripla_BP_4; pfam13407"
                     /db_xref="CDD:222108"
     misc_feature    order(1439703..1439705,1439940..1439942,1440105..1440107,
                     1440387..1440389,1440447..1440449)
                     /locus_tag="Smed_4930"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:107249"
     gene            complement(1440647..1442044)
                     /locus_tag="Smed_4931"
                     /db_xref="GeneID:5318247"
     CDS             complement(1440647..1442044)
                     /locus_tag="Smed_4931"
                     /note="PFAM: glycoside hydrolase family 16; Hemolysin-type
                     calcium-binding region;
                     KEGG: sme:SMb20932 endo-1,3-1,4-beta-glycanase, C-terminal
                     secretion signal protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="YP_001313646.1"
                     /db_xref="GI:150377050"
                     /db_xref="InterPro:IPR000757"
                     /db_xref="InterPro:IPR001343"
                     /db_xref="GeneID:5318247"
                     /translation="MSRTILNAVGTPLYYSGSSTAWFSATGSGPTLYGTAGNDSIWGD
                     SSVNVTMIGGRGDDIYYLYSSINRAFEAAGEGVDTINTWMSYTLPENFENLTVTGNGR
                     SAFGNETDNIIKGGSGSQTIDGRGGNDVLIGAGGADTFVFARGNGSDLITDFNYDDII
                     RLDDYGFTSFEQVLANVAQEGADLRLHLADGESLVFANTTADELEARQFRLSLDRSVL
                     SQTFSDEFNTLDLRNGTSGVWDAKYWWAPEKGATLSSNGEQQWYINPSYAPTASANPF
                     SVSNGVLTITAAPASEAIQAEINGYDYTSGMLTTHSSFAQTYGYFEMRADMPDDHGVW
                     PAFWLLPADGSWPPELDVVEMRGQDSNTVITTVHSNETGSRASIENAVKVADASGFHT
                     YGVLWTEEEIVWYFDDAAIARADTPADMHDPMYMLVNLAVGGMAGTPNDGLVDGSEMK
                     IDYIRAYALDADWQI"
     misc_feature    complement(1441373..>1441972)
                     /locus_tag="Smed_4931"
                     /note="RTX toxins and related Ca2+-binding proteins
                     [Secondary metabolites biosynthesis, transport, and
                     catabolism]; Region: COG2931"
                     /db_xref="CDD:225483"
     misc_feature    complement(<1440656..1441381)
                     /locus_tag="Smed_4931"
                     /note="Beta-glucanase/Beta-glucan synthetase [Carbohydrate
                     transport and metabolism]; Region: SKN1; COG2273"
                     /db_xref="CDD:225182"
     misc_feature    complement(1440674..1441381)
                     /locus_tag="Smed_4931"
                     /note="Laminarinase, member of the glycosyl hydrolase
                     family 16; Region: GH16_laminarinase_like; cd08023"
                     /db_xref="CDD:185693"
     misc_feature    complement(order(1440941..1440943,1440983..1440985,
                     1440992..1440994,1440998..1441000,1441031..1441033,
                     1441043..1441045,1441124..1441126))
                     /locus_tag="Smed_4931"
                     /note="active site"
                     /db_xref="CDD:185693"
     misc_feature    complement(order(1440983..1440985,1440992..1440994,
                     1440998..1441000))
                     /locus_tag="Smed_4931"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:185693"
     gene            1442210..1444933
                     /locus_tag="Smed_4932"
                     /db_xref="GeneID:5318248"
     CDS             1442210..1444933
                     /locus_tag="Smed_4932"
                     /note="TIGRFAM: PAS sensor protein;
                     PFAM: GAF domain protein; HWE histidine kinase; PAS fold-3
                     domain protein; PAS fold-4 domain protein; PAS fold domain
                     protein;
                     SMART: PAS domain containing protein; PAC
                     repeat-containing protein;
                     KEGG: sme:SMb20933 putative two-component sensor histidine
                     kinase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine kinase"
                     /protein_id="YP_001313647.1"
                     /db_xref="GI:150377051"
                     /db_xref="InterPro:IPR000014"
                     /db_xref="InterPro:IPR000700"
                     /db_xref="InterPro:IPR001610"
                     /db_xref="InterPro:IPR003018"
                     /db_xref="InterPro:IPR011102"
                     /db_xref="InterPro:IPR013655"
                     /db_xref="InterPro:IPR013656"
                     /db_xref="InterPro:IPR013767"
                     /db_xref="GeneID:5318248"
                     /translation="MHGAEILPKGVFDDETSLHEPDFRAVLDALTVAVYATDAEGVVT
                     YCNAAAAAIAGREPELGKDRWCVSWQLRRPDGSPLPHEQCPMARALKERRPIRGEELI
                     AVRPNGAAVPLLPHPTPMFDAAGALTGAVNVLIDLSNTKDMERSSRYLAAIVESSDDA
                     IVAKDLNGIITSWNRGAERLFGYTAEDVIGKSITILIPQDRLSEEPGILERIRRGDKV
                     DHFETKRRRKDGSLIDISLTVSPVRDATGRIVGASKIARDVTETKRAAEALSDRFREQ
                     AALYRFTERVQRTKRIEDVFEAALDAILEALSCDRASILLFDPSGTMRFVASRGLSEA
                     YQSAVDGHSPWASGASEPEPIFVENVDSTDMSRALKEAIAQEGIGALGFFPLVLDGKL
                     IGKFMTYYDEPHRFAESEIGVAVTIARQLGFSLQRMETENARRQAEERLRRNEANERA
                     RAGELAAIMEAVPALIWIARTPDCHVISGNKSSYEMLRLPHDSNLSLSAPPGERPTNF
                     RVFSGGRALSPDELPVQRAARGEEVRNFEEEVWFEDGSSRYIFGNATPLRDAAGEVIG
                     AVAASVDITERRQAEEALQESERRLQLALDAGHMGAWEWNLGTDEVIWSPGLEALHRL
                     ERGSFGRTLADFKRNVHPDDLPLIDREIAKAVETKGDYHVVYRARLLDGTVRWMEAFA
                     QFSPSNGPSRRLIGVCMDITERREAEAQRNLLVAELSHRVKNTLAIVGSIARQTFSTS
                     PDARTAHRSFDARIRALAQTHTRLAEASWSGVSLQTVLYDELAPYQDDGRTNVKLQGP
                     TAMLPPKHALTLGMAAHELATNAAKHGALSVKSGKVDIEWVVDVDTDRLRICWRESGG
                     PPVVTPAHNGFGRLLLERVLASDLGGEVHLEFKPQGLVCTIDVPYPRGAPG"
     misc_feature    1442309..1442623
                     /locus_tag="Smed_4932"
                     /note="PAS domain; Region: PAS_9; pfam13426"
                     /db_xref="CDD:222120"
     misc_feature    1442645..1443016
                     /locus_tag="Smed_4932"
                     /note="PAS domain S-box; Region: sensory_box; TIGR00229"
                     /db_xref="CDD:232884"
     misc_feature    1442678..1442986
                     /locus_tag="Smed_4932"
                     /note="PAS domain; PAS motifs appear in archaea,
                     eubacteria and eukarya. Probably the most surprising
                     identification of a PAS domain was that in EAG-like
                     K+-channels. PAS domains have been found to bind ligands,
                     and to act as sensors for light and oxygen in...; Region:
                     PAS; cd00130"
                     /db_xref="CDD:238075"
     misc_feature    order(1442726..1442728,1442738..1442740,1442756..1442758,
                     1442795..1442806,1442882..1442884,1442897..1442899)
                     /locus_tag="Smed_4932"
                     /note="putative active site [active]"
                     /db_xref="CDD:238075"
     misc_feature    order(1442786..1442788,1442798..1442800,1442822..1442824,
                     1442831..1442836,1442918..1442920,1442924..1442926)
                     /locus_tag="Smed_4932"
                     /note="heme pocket [chemical binding]; other site"
                     /db_xref="CDD:238075"
     misc_feature    1443029..1443496
                     /locus_tag="Smed_4932"
                     /note="FOG: GAF domain [Signal transduction mechanisms];
                     Region: FhlA; COG2203"
                     /db_xref="CDD:225113"
     misc_feature    1443083..1443484
                     /locus_tag="Smed_4932"
                     /note="GAF domain; Region: GAF; pfam01590"
                     /db_xref="CDD:216590"
     misc_feature    1443623..1443937
                     /locus_tag="Smed_4932"
                     /note="PAS domain; Region: PAS_9; pfam13426"
                     /db_xref="CDD:222120"
     misc_feature    <1443839..1443940
                     /locus_tag="Smed_4932"
                     /note="Motif C-terminal to PAS motifs (likely to
                     contribute to PAS structural domain); Region: PAC;
                     smart00086"
                     /db_xref="CDD:197509"
     misc_feature    1444004..1444312
                     /locus_tag="Smed_4932"
                     /note="PAS domain; PAS motifs appear in archaea,
                     eubacteria and eukarya. Probably the most surprising
                     identification of a PAS domain was that in EAG-like
                     K+-channels. PAS domains have been found to bind ligands,
                     and to act as sensors for light and oxygen in...; Region:
                     PAS; cd00130"
                     /db_xref="CDD:238075"
     misc_feature    1444049..1444300
                     /locus_tag="Smed_4932"
                     /note="PAS fold; Region: PAS_3; pfam08447"
                     /db_xref="CDD:219844"
     misc_feature    order(1444049..1444051,1444061..1444063,1444076..1444078,
                     1444115..1444117,1444127..1444135,1444211..1444213,
                     1444226..1444228)
                     /locus_tag="Smed_4932"
                     /note="putative active site [active]"
                     /db_xref="CDD:238075"
     misc_feature    order(1444106..1444108,1444127..1444129,1444151..1444153,
                     1444160..1444165,1444247..1444249,1444250..1444252)
                     /locus_tag="Smed_4932"
                     /note="heme pocket [chemical binding]; other site"
                     /db_xref="CDD:238075"
     misc_feature    1444307..1444918
                     /locus_tag="Smed_4932"
                     /note="Signal transduction histidine kinase [Signal
                     transduction mechanisms]; Region: COG3920"
                     /db_xref="CDD:226434"
     misc_feature    1444358..1444606
                     /locus_tag="Smed_4932"
                     /note="HWE histidine kinase; Region: HWE_HK; pfam07536"
                     /db_xref="CDD:148894"
     gene            1444930..1445295
                     /locus_tag="Smed_4933"
                     /db_xref="GeneID:5318249"
     CDS             1444930..1445295
                     /locus_tag="Smed_4933"
                     /note="PFAM: response regulator receiver;
                     KEGG: sme:SMb20934 putative two-component response
                     regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver protein"
                     /protein_id="YP_001313648.1"
                     /db_xref="GI:150377052"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="GeneID:5318249"
                     /translation="MNAGNRCRVLVVEDEFLVALQIEADLLAAGYMVVGPFTSLAQSI
                     SAARAHPFDIATLDLNLRGEFAYPLVDELVDRKVPVLLLTGYAAHDLPERFRALPRLA
                     KPFDGTQLIRKISDIYPVS"
     misc_feature    1444933..1445286
                     /locus_tag="Smed_4933"
                     /note="FOG: CheY-like receiver [Signal transduction
                     mechanisms]; Region: CheY; COG0784"
                     /db_xref="CDD:223855"
     misc_feature    1444957..1445280
                     /locus_tag="Smed_4933"
                     /note="Signal receiver domain; originally thought to be
                     unique to bacteria (CheY, OmpR, NtrC, and PhoB), now
                     recently identified in eukaroytes ETR1 Arabidopsis
                     thaliana; this domain receives the signal from the sensor
                     partner in a two-component systems; Region: REC; cd00156"
                     /db_xref="CDD:238088"
     misc_feature    order(1444966..1444971,1445101..1445103,1445125..1445127,
                     1445179..1445181,1445236..1445241)
                     /locus_tag="Smed_4933"
                     /note="active site"
                     /db_xref="CDD:238088"
     misc_feature    1445101..1445103
                     /locus_tag="Smed_4933"
                     /note="phosphorylation site [posttranslational
                     modification]"
                     /db_xref="CDD:238088"
     misc_feature    order(1445110..1445115,1445119..1445127)
                     /locus_tag="Smed_4933"
                     /note="intermolecular recognition site; other site"
                     /db_xref="CDD:238088"
     misc_feature    1445236..1445244
                     /locus_tag="Smed_4933"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238088"
     gene            complement(1445354..1445605)
                     /locus_tag="Smed_4934"
                     /db_xref="GeneID:5318250"
     CDS             complement(1445354..1445605)
                     /locus_tag="Smed_4934"
                     /note="PFAM: helix-turn-helix domain protein;
                     KEGG: sme:SMb20935 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="YP_001313649.1"
                     /db_xref="GI:150377053"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="GeneID:5318250"
                     /translation="MSISHSNIAHKEAALVPNGDIAARVKAAREAVGYSIEDLAVTCG
                     LAVVEINDIENGTDFSPAKLKRVAGALQVPVSHFLPTEM"
     misc_feature    complement(<1445360..1445548)
                     /locus_tag="Smed_4934"
                     /note="Predicted transcriptional regulators
                     [Transcription]; Region: HipB; COG1396"
                     /db_xref="CDD:224314"
     misc_feature    complement(1445372..1445542)
                     /locus_tag="Smed_4934"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; Region: HTH_XRE; cd00093"
                     /db_xref="CDD:238045"
     misc_feature    complement(order(1445441..1445443,1445516..1445518,
                     1445528..1445530))
                     /locus_tag="Smed_4934"
                     /note="non-specific DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238045"
     misc_feature    complement(order(1445444..1445446,1445519..1445521))
                     /locus_tag="Smed_4934"
                     /note="salt bridge; other site"
                     /db_xref="CDD:238045"
     misc_feature    complement(order(1445438..1445443,1445453..1445455,
                     1445462..1445464,1445495..1445500))
                     /locus_tag="Smed_4934"
                     /note="sequence-specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238045"
     gene            1445713..1445916
                     /locus_tag="Smed_4935"
                     /db_xref="GeneID:5318262"
     CDS             1445713..1445916
                     /locus_tag="Smed_4935"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313650.1"
                     /db_xref="GI:150377054"
                     /db_xref="GeneID:5318262"
                     /translation="MQQIKVLQRPSASEDAALQDDGNVLCHRCNMDKPKSSLYTAGAS
                     EGLEGFPEFSGCKEVIRRAGGEA"
     gene            1446421..1448241
                     /locus_tag="Smed_4936"
                     /db_xref="GeneID:5318263"
     CDS             1446421..1448241
                     /locus_tag="Smed_4936"
                     /note="PFAM: ABC transporter related; SbmABacA family
                     protein; ABC transporter domain protein;
                     KEGG: sme:SMb20937 putative ABC transporter protein
                     consisting of fused ATP-binding and permease components"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="YP_001313651.1"
                     /db_xref="GI:150377055"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR009248"
                     /db_xref="InterPro:IPR010509"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="GeneID:5318263"
                     /translation="MKNQTGKRKKDRTPAAPPEVSNIWQQFEMMRHAFAASPVLKPIL
                     WLTTGSFAVIVATAIGQVVLNRWYRPFFDAIERRDINSFFYQLMLFVAIAGVLLVFNV
                     GQQWLNQMVRLKLREGLTLDLINEWMRPRRAFRLANAGTIGVNPDQRMQEDAGHLADL
                     TTGLGFGLVQSSIMLISFVGVLWSLSAGFAFDIGGQKLEIPGYMVWAAILYAGSASWL
                     SWLVGRRMIVLNGERYAREADLRFSMMHANEHIDGISLAGGEAGERRRLQLDLASVLV
                     ATRNIFRAEINLAWVQDGYGWVTVVAPILVAAPVYFAGNISFGGLMMAVGAFNQVHSS
                     LKWFVANVSAITDWRATLLRVAAFRRALVAADTLHGDEKRIEFVENDRDVMTLDNLEV
                     VSPSGRTSLAESRIEIAPGQRVNIIGDPHAGKTLLFRAVAGLWPWGSGRVGMPAGEAV
                     AFIPRAPYFPRGRLRDALAYPHADEFADSVLVSALSKVGLDHLATSLNREARWERELG
                     EDDQRLLAFARLLVQKPRWVVIDEALESMDSDALKRALSIFEVDLRETAVIKIGRTPR
                     NGGLFSRVIRIVKDADAPALKPVRLGGGVAELELAARSAP"
     misc_feature    1446487..1448205
                     /locus_tag="Smed_4936"
                     /note="ABC-type uncharacterized transport system, permease
                     and ATPase components [General function prediction only];
                     Region: COG4178"
                     /db_xref="CDD:226646"
     misc_feature    1446544..1447356
                     /locus_tag="Smed_4936"
                     /note="ABC transporter transmembrane region 2; Region:
                     ABC_membrane_2; cl00549"
                     /db_xref="CDD:241940"
     misc_feature    1447573..1448163
                     /locus_tag="Smed_4936"
                     /note="ATP-binding cassette domain of peroxisomal
                     transporter, subfamily D; Region: ABCD_peroxisomal_ALDP;
                     cd03223"
                     /db_xref="CDD:213190"
     gene            complement(1448254..1448991)
                     /locus_tag="Smed_4937"
                     /db_xref="GeneID:5318264"
     CDS             complement(1448254..1448991)
                     /locus_tag="Smed_4937"
                     /note="PFAM: Radical SAM domain protein;
                     KEGG: sme:SMb20938 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM domain-containing protein"
                     /protein_id="YP_001313652.1"
                     /db_xref="GI:150377056"
                     /db_xref="InterPro:IPR007197"
                     /db_xref="GeneID:5318264"
                     /translation="MTNVRSDEIRVSEIFGPTIQGEGVLIGLPTVFVRSGGCDYRCSW
                     CDSLHAVESSYRHEWHAMSTEAVWQEIVRLSRGEAVMVSLSGGNPAIQPFGDLIGRGH
                     RNGYRFALETQGSIAREWFAELDVLVLSPKPPSSGMETDWQAFDVCLRMAAGKPQTVL
                     KFVVFDEADYAYARAAAARHPHLPVYLQPGNHTPPPSDDKDAPIDLEGVMERMRWLVD
                     ATIEDGWFEARVLPQLHVLIWGNKRGV"
     misc_feature    complement(1448257..1448970)
                     /locus_tag="Smed_4937"
                     /note="7-cyano-7-deazaguanosine (preQ0) biosynthesis
                     protein QueE; Region: Bsubt_queE; TIGR03365"
                     /db_xref="CDD:132408"
     misc_feature    complement(<1448650..1448940)
                     /locus_tag="Smed_4937"
                     /note="putative 7-cyano-7-deazaguanosine (preQ0)
                     biosynthesis protein QueE; Region: rSAM_QueE_Ecoli;
                     TIGR04322"
                     /db_xref="CDD:213935"
     gene            complement(1448988..1449344)
                     /locus_tag="Smed_4938"
                     /db_xref="GeneID:5318265"
     CDS             complement(1448988..1449344)
                     /locus_tag="Smed_4938"
                     /note="PFAM: 6-pyruvoyl tetrahydropterin synthase and
                     hypothetical protein;
                     KEGG: sme:SMb20939 6-pyruvoyltetrahydropterin synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-pyruvoyl tetrahydropterin synthase"
                     /protein_id="YP_001313653.1"
                     /db_xref="GI:150377057"
                     /db_xref="InterPro:IPR007115"
                     /db_xref="GeneID:5318265"
                     /translation="MFRITKEFHFSASHQLKNLPPEHQCARLHGHNYIVEVELSGETL
                     NEHGFVRDYHELAPLKTYIDEAFDHRHLNDVLGHDRVTAECLARHFYEWCKARLFETT
                     AVRVSETAKTWAEYRP"
     misc_feature    complement(1448991..1449344)
                     /locus_tag="Smed_4938"
                     /note="6-pyruvoyl-tetrahydropterin synthase [Coenzyme
                     metabolism]; Region: COG0720"
                     /db_xref="CDD:223792"
     misc_feature    complement(order(1449003..1449005,1449021..1449023,
                     1449252..1449254,1449258..1449260))
                     /locus_tag="Smed_4938"
                     /note="active site"
                     /db_xref="CDD:238351"
     gene            complement(1449344..1450054)
                     /locus_tag="Smed_4939"
                     /db_xref="GeneID:5318266"
     CDS             complement(1449344..1450054)
                     /locus_tag="Smed_4939"
                     /note="TIGRFAM: exsB protein;
                     PFAM: ExsB family protein;
                     KEGG: sme:SMb20940 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="exsB protein"
                     /protein_id="YP_001313654.1"
                     /db_xref="GI:150377058"
                     /db_xref="InterPro:IPR004479"
                     /db_xref="GeneID:5318266"
                     /translation="MKTIVICSGGLDSVSLAHKVAAEQELVCLLSFDYGQRHRKELDF
                     AAVCARRLGVPHQIIDIREIGRHLTGSALTDEVDVPDGHYAEETMKTTVVPNRNAIML
                     AIAFGVAAARKADAVATAVHGGDHFIYPDCRPGFIDAFQAMQNHALDGYADVGLYAPY
                     VNVAKAEIVADGSRYGTPFAETWSCYKGGARHCGRCGTCVERREAFHLADVADPTAYD
                     DADFWVTVTGSFVAEEVE"
     misc_feature    complement(1449434..1450051)
                     /locus_tag="Smed_4939"
                     /note="ExsB is a transcription regulator related protein.
                     It is a subfamily of a Adenosine nucleotide binding
                     superfamily of proteins. This protein family is
                     represented by a single member in nearly every completed
                     large (&gt; 1000 genes) prokaryotic genome. In...; Region:
                     ExsB; cd01995"
                     /db_xref="CDD:238953"
     misc_feature    complement(order(1449944..1449946,1449950..1449952,
                     1450016..1450027,1450031..1450039))
                     /locus_tag="Smed_4939"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238953"
     gene            1450273..1451187
                     /locus_tag="Smed_4940"
                     /db_xref="GeneID:5318267"
     CDS             1450273..1451187
                     /locus_tag="Smed_4940"
                     /note="PFAM: protein of unknown function DUF6
                     transmembrane;
                     KEGG: rsp:RSP_2053 possible transporter, RarD family, DMT
                     superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313655.1"
                     /db_xref="GI:150377059"
                     /db_xref="InterPro:IPR000620"
                     /db_xref="GeneID:5318267"
                     /translation="MQQANSHDRHLDNIPLAVGVIILTVLALSLGDALIKMSSGSFVI
                     WQIFVIRSMIAIPVLLLILIMAAPDTLRMPDDLVWIILRSLMLVAMWVCYYVSLPKLT
                     LSAAAAAYYTLPIFITLFSALFIGSKISQKGWLAVFAGFSGVVLILRPKAGDFNAYAV
                     LPLASAMLYAAAMILTRTRCRNQHPVILSLALNAAFVIVGVAAASLIPLLPDTARQGF
                     LLAPWAAMGWSEWISMMLLAGVILTGSIGAAIAYQNGPPAMIGAFDFAYVGFAVIWGI
                     VFFAEVPDTSSVLGIGLIVSAGILSLRQ"
     misc_feature    1450306..1451181
                     /locus_tag="Smed_4940"
                     /note="Permeases of the drug/metabolite transporter (DMT)
                     superfamily [Carbohydrate transport and metabolism / Amino
                     acid transport and metabolism / General function
                     prediction only]; Region: RhaT; COG0697"
                     /db_xref="CDD:223769"
     gene            complement(1451368..1453182)
                     /locus_tag="Smed_4941"
                     /db_xref="GeneID:5318268"
     CDS             complement(1451368..1453182)
                     /locus_tag="Smed_4941"
                     /note="PFAM: ABC transporter transmembrane region; ABC
                     transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20941 msbA-like saccharide exporting ABC
                     transporter protein, consisting of ATP-binding and
                     permease domains"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313656.1"
                     /db_xref="GI:150377060"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="GeneID:5318268"
                     /translation="MAFTRFTARNRAFLSVFRFSWAHWKRQPVRLAALLTAVLFSTLA
                     DVLTPLYSGRLVDAVVSGAASDEIAWNAAMAAFMMLMALSLGAIVLRHVTFMGIVSLT
                     LKMMSDIAAAAFHHIQRFSSDWHANSFAGSTVRKVTRGMWALDLLNDTLLVALFPSVV
                     MLVGSTALMAWYWPMMGVIIGLGSIVFIVVTVSLSLGYVAPMASLANSWDTRLGGALA
                     DAVSCNPVVKAFGAEGREDARLAKVLRKWENRTRRTWSRGTLNGTAQGAMLLVLRAAV
                     IGFALLLWARGQATAGDITFVLTSFFILQGYLREVGMHIRNLQRSINDMEELVAIHDQ
                     SLGVEDRPGAKPIRITEGGIEFRDVTFHYGAHRAPLYQGFSVSIAAGERVGLVGHSGS
                     GKTTFIKLIQRLHDLNAGEIRIDGQNIADFTQASLRQQIAIVQQEPILFHRSLAENIA
                     YARPGATQRDIEEAARLASAHDFITELPKGYATLVGERGVKLSGGERQRVAIARAFLA
                     DAPILILDEATSSLDSESEVLIQQAMERLMTGRTTLVVAHRLSTVRALDRLLVFDRGR
                     IAEEGDHGALIRVKGGIYRSLFERQALELTKGLILSEG"
     sig_peptide     complement(1453048..1453182)
                     /locus_tag="Smed_4941"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.994) with cleavage site probability 0.796 at
                     residue 45"
     misc_feature    complement(1451401..1453143)
                     /locus_tag="Smed_4941"
                     /note="ABC-type multidrug transport system, ATPase and
                     permease components [Defense mechanisms]; Region: MdlB;
                     COG1132"
                     /db_xref="CDD:224055"
     misc_feature    complement(1452259..1453092)
                     /locus_tag="Smed_4941"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:216049"
     misc_feature    complement(1451419..1452123)
                     /locus_tag="Smed_4941"
                     /note="ATP-binding cassette domain of the bacterial lipid
                     flippase and related proteins, subfamily C; Region:
                     ABCC_MsbA; cd03251"
                     /db_xref="CDD:213218"
     misc_feature    complement(1451998..1452021)
                     /locus_tag="Smed_4941"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(order(1451539..1451541,1451632..1451637,
                     1451875..1451877,1451995..1452003,1452007..1452012))
                     /locus_tag="Smed_4941"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(1451875..1451886)
                     /locus_tag="Smed_4941"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(1451680..1451709)
                     /locus_tag="Smed_4941"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(1451632..1451649)
                     /locus_tag="Smed_4941"
                     /note="Walker B; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(1451614..1451625)
                     /locus_tag="Smed_4941"
                     /note="D-loop; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(1451533..1451553)
                     /locus_tag="Smed_4941"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213218"
     gene            1453711..1454697
                     /locus_tag="Smed_4942"
                     /db_xref="GeneID:5318269"
     CDS             1453711..1454697
                     /locus_tag="Smed_4942"
                     /note="TIGRFAM: UDP-glucose 4-epimerase;
                     PFAM: NAD-dependent epimerase/dehydratase; short-chain
                     dehydrogenase/reductase SDR; 3-beta hydroxysteroid
                     dehydrogenase/isomerase; polysaccharide biosynthesis
                     protein CapD; dTDP-4-dehydrorhamnose reductase; Male
                     sterility domain;
                     KEGG: sme:SMb20942 UDP glucose 4-epimerase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="YP_001313657.1"
                     /db_xref="GI:150377061"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005886"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318269"
                     /translation="MQNNNILVVGGAGYIGSHTCLQLAAKGYQPVVYDNLSNGHEEFV
                     KWGVLEKGDIRDRQRLDEVLARHKPRAILHFAAMIEVGESVKDPAAFYDNNVIGTLTL
                     LSAALAAGIDAFVFSSTCATYGLPDSVPMNETHKQAPINPYGRTKWICEQALKDYDHY
                     KGLRSVILRYFNAAGADFEGRIGEWHEPETHAIPLAIDAALGRREGFKVFGTDYDTRD
                     GTCVRDYIHVLDLADAHVRAVDYLLEGGESVALNLGTGTGTTVKELLNAIEDVAGRSF
                     NIGYAERREGDSTTLVANNDKAREVLGWEPQYDLAAITRSAWNWHSRRNQGA"
     misc_feature    1453720..1454691
                     /locus_tag="Smed_4942"
                     /note="UDP-glucose 4-epimerase [Cell envelope biogenesis,
                     outer membrane]; Region: GalE; COG1087"
                     /db_xref="CDD:224012"
     misc_feature    1453723..1454676
                     /locus_tag="Smed_4942"
                     /note="UDP-glucose 4 epimerase, subgroup 1, extended (e)
                     SDRs; Region: UDP_G4E_1_SDR_e; cd05247"
                     /db_xref="CDD:187558"
     misc_feature    order(1453738..1453740,1453744..1453755,1453810..1453827,
                     1453864..1453872,1453933..1453941,1453945..1453947,
                     1453990..1453992,1454059..1454067,1454137..1454139,
                     1454149..1454151,1454218..1454223,1454227..1454229)
                     /locus_tag="Smed_4942"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187558"
     misc_feature    order(1453963..1453965,1453969..1453977,1453984..1453989,
                     1453996..1454001,1454008..1454013,1454017..1454022,
                     1454029..1454031,1454134..1454136,1454143..1454145,
                     1454155..1454157,1454164..1454169,1454173..1454181)
                     /locus_tag="Smed_4942"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187558"
     misc_feature    order(1453993..1453995,1454065..1454067,1454137..1454139,
                     1454149..1454151)
                     /locus_tag="Smed_4942"
                     /note="active site"
                     /db_xref="CDD:187558"
     misc_feature    order(1454065..1454073,1454137..1454139,1454218..1454226,
                     1454278..1454286,1454329..1454340,1454371..1454373,
                     1454377..1454379,1454383..1454385,1454491..1454493,
                     1454560..1454562,1454569..1454571)
                     /locus_tag="Smed_4942"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187558"
     gene            complement(1454765..1455772)
                     /locus_tag="Smed_4943"
                     /db_xref="GeneID:5318270"
     CDS             complement(1454765..1455772)
                     /locus_tag="Smed_4943"
                     /note="PFAM: acyltransferase 3;
                     KEGG: sme:SMb20943 acetyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase 3"
                     /protein_id="YP_001313658.1"
                     /db_xref="GI:150377062"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="GeneID:5318270"
                     /translation="MKTIYGIQYLRAAAALAVVFFHAAEKTGHHFTIGAAGVDVFFVI
                     SGFIMWVISDRRPVTPLEFIRDRARRIVPVYWLATAVMVAGALAGLFPNLVLSLEHVL
                     ASLFFVPARSPSSGEVWPVLVQGWTLNFEMLFYLVFAGSLVLPRNWRLPAMSGLFLAL
                     VIAGRVATFDGTLMLTYTRPIILEFVAGMIIAEFWLKGRVPPLAVGSALMACSLGGFA
                     LIGLLALPFDELITGPLAVLLVLGVLSLEANGCVRRVPLPALLGDASYSIYLWHTFAI
                     SVVAKVALEIDLGAPATMFMAVLSGTLIGIAAYMMLERPLMRRGNARRVAGGLAGRAA
                     E"
     misc_feature    complement(1454822..1455673)
                     /locus_tag="Smed_4943"
                     /note="Predicted acyltransferases [Lipid metabolism];
                     Region: COG1835"
                     /db_xref="CDD:224748"
     gene            complement(1455769..1457073)
                     /locus_tag="Smed_4944"
                     /db_xref="GeneID:5318271"
     CDS             complement(1455769..1457073)
                     /locus_tag="Smed_4944"
                     /note="PFAM: O-antigen polymerase;
                     KEGG: sme:SMb20944 putative polysaccharide polymerase,
                     similar to Wzy protein"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="YP_001313659.1"
                     /db_xref="GI:150377063"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="GeneID:5318271"
                     /translation="MRISKASLVRPGANDVFGTFALALSVFVFAYSARFGQVSILAYY
                     GLWLPLVLVDYRKVLGNYASYLWILSFTIFACLTIFWSAAPSLSLRTGIQYLSHVVCA
                     LIAMRTIDIRTLTRGMIAGVAIVLLYSLLFGSYHYDPLDGTYSFVGAFASKNQLGFYA
                     SLGIYFAFAAVFVLGERGLWMGAAGGGGLLAAYCLLMSQSATSVLTTAAVIGLCLGMR
                     AITTLRPASRKILFTAASVFGGVAAVAIIYAGGIDMILGAFGKDSTLTGRTYLWQQGI
                     EAAKASPLVGIGYQAYWVQGFSEAERLWEEFYIGSRAGFHFHNTFIETAVETGLIGLV
                     LLTMVLAMTFFGQLKRLLSEDCDPESMVLFGVGALLLVRAFVEIDILTPYHIGSFLLY
                     FTAGKLTIPRRRVAALPWPPQLHPAPYGRAFTPMMQRPGENR"
     misc_feature    complement(1455850..1457073)
                     /locus_tag="Smed_4944"
                     /note="Lipid A core - O-antigen ligase and related enzymes
                     [Cell envelope biogenesis, outer membrane]; Region: RfaL;
                     COG3307"
                     /db_xref="CDD:225844"
     sig_peptide     complement(1456981..1457073)
                     /locus_tag="Smed_4944"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.914) with cleavage site probability 0.869 at
                     residue 31"
     misc_feature    complement(1456066..1456485)
                     /locus_tag="Smed_4944"
                     /note="O-Antigen ligase; Region: Wzy_C; pfam04932"
                     /db_xref="CDD:218334"
     gene            complement(1457081..1458349)
                     /locus_tag="Smed_4945"
                     /db_xref="GeneID:5318272"
     CDS             complement(1457081..1458349)
                     /locus_tag="Smed_4945"
                     /note="PFAM: polysaccharide export protein;
                     KEGG: sme:SMb20945 hypothetical outer membrane protein,
                     similar to Wza, OMA family"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="YP_001313660.1"
                     /db_xref="GI:150377064"
                     /db_xref="InterPro:IPR003715"
                     /db_xref="GeneID:5318272"
                     /translation="MQSNRLPGASAGSRMASCLTRLVLMAALAASATSLARADEYRLG
                     VMDKLRVRVAEWQTAEGAVRDWSAVSGDYTVGASGSISLPFVGELPASGKTTAEVAEE
                     IGVKMQKLFGLRDRPSASVEMAQYRPVYLSGEVQTPGEYPYAPNMTVLKAVSLGGGLR
                     RADNGQRFARDYINASGESAVQVAERSRLLIRRARLQAEIGKRDSIGMPEELKNVPGA
                     DELLASETALMESRDKRQKRQLDALADLRSLLQSEIEALAKKAETQARQLELATEDRD
                     KVDSLAEKGLALSQRKLSLEQRVADVQASLLDIDTASLKAKQDASKAAQDETNLRNDW
                     DAQLAQELQNTEAELDTLALKLGTSRDLMTEALLQSADAAQLEQQAAQITYSIIRDKD
                     GKPTEIAADENTPVLPGDVIKVNTALAAMR"
     sig_peptide     complement(1458233..1458349)
                     /locus_tag="Smed_4945"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.718 at
                     residue 39"
     misc_feature    complement(<1457825..1458235)
                     /locus_tag="Smed_4945"
                     /note="Periplasmic protein involved in polysaccharide
                     export, contains    SLBB domain of b-grasp fold [Cell
                     wall/membrane/envelope biogenesis]; Region: Wza; COG1596"
                     /db_xref="CDD:224512"
     misc_feature    complement(1457975..1458235)
                     /locus_tag="Smed_4945"
                     /note="Polysaccharide biosynthesis/export protein; Region:
                     Poly_export; pfam02563"
                     /db_xref="CDD:202285"
     misc_feature    complement(<1457849..1457965)
                     /locus_tag="Smed_4945"
                     /note="SLBB domain; Region: SLBB; pfam10531"
                     /db_xref="CDD:220798"
     gene            complement(1458403..1459083)
                     /locus_tag="Smed_4946"
                     /db_xref="GeneID:5318157"
     CDS             complement(1458403..1459083)
                     /locus_tag="Smed_4946"
                     /EC_number="2.7.8.6"
                     /note="PFAM: sugar transferase;
                     KEGG: sme:SMb20946 galactosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate galactose
                     phosphotransferase"
                     /protein_id="YP_001313661.1"
                     /db_xref="GI:150377065"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="GeneID:5318157"
                     /translation="MKSATRSASSPFFIPDDTGAVRPIGGMAKRSFDIVAASVALLLF
                     SPLFLLIMALVKFSDGGRVFYGHRRIGHNGQSFKCLKFRTMMERGDQILEDYFKANPD
                     AYEEWCATRKLQNDPRVTVVGAVLRKLSLDELPQLLNIIRGEMSVVGPRPVVEDELEL
                     YDSAAEFYLRSRPGLTGLWQISGRNDVSYATRVAFDTQYVQNWSLLVDFVIVFKTIPA
                     VCLSRGSY"
     misc_feature    complement(1458406..1458999)
                     /locus_tag="Smed_4946"
                     /note="Bacterial sugar transferase; Region: Bac_transf;
                     pfam02397"
                     /db_xref="CDD:217016"
     gene            1459843..1460139
                     /locus_tag="Smed_4947"
                     /db_xref="GeneID:5318158"
     CDS             1459843..1460139
                     /locus_tag="Smed_4947"
                     /note="KEGG: sme:SMb20947 posttranscriptional regulator,
                     repressor protein"
                     /codon_start=1
                     /transl_table=11
                     /product="posttranscriptional regulator, repressor
                     protein"
                     /protein_id="YP_001313662.1"
                     /db_xref="GI:150377066"
                     /db_xref="GeneID:5318158"
                     /translation="MFAPRVFVSMIGALAAFAVATYYLNGSLASTAIQTLICAVLMQV
                     GYFAAILFLVWKEARERRRVSLQKPFVTAEAANDEKQSGKVPLRRLNRPHHFNS"
     sig_peptide     1459843..1459899
                     /locus_tag="Smed_4947"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.982) with cleavage site probability 0.446 at
                     residue 19"
     misc_feature    1459894..1460007
                     /locus_tag="Smed_4947"
                     /note="Exopolysaccharide production repressor; Region:
                     SyrA; pfam11089"
                     /db_xref="CDD:151534"
     gene            1460367..1461395
                     /locus_tag="Smed_4948"
                     /db_xref="GeneID:5318159"
     CDS             1460367..1461395
                     /locus_tag="Smed_4948"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb20948 glucosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313663.1"
                     /db_xref="GI:150377067"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318159"
                     /translation="MTAAVPTNVCIIIAAKNAADTIARAVSSALAEPEAAEVVVIDDG
                     STDDSAAVARAADDGSGRLNVVRFEENRGPAAARNHAIEISKSQLLGVLDADDFLFPG
                     RLRQLLSQEGWDFIADNIAFIDAAQAANAQASIDRFAPAPRLIDLVGFIEGNISRRGV
                     RRGEIGFLKPLMRRAFLDQHGLRYNETLRLGEDYDLYARALAKGARYKIIHSCGYAAV
                     VRGDSLSGSHRTIDLKRLYEADRAILAGNKLSNDAEAALRRHERHIRDRYELRHFLDL
                     KNQRGFARAISYALTHPAALPAILGGILADKTERFRPSRAPAPLALGGTGDVRYLLEA
                     LAMDQPQK"
     misc_feature    1460397..1460987
                     /locus_tag="Smed_4948"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cd00761"
                     /db_xref="CDD:132997"
     misc_feature    order(1460406..1460408,1460412..1460414,1460646..1460648,
                     1460652..1460654)
                     /locus_tag="Smed_4948"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            complement(1461386..1462336)
                     /locus_tag="Smed_4949"
                     /db_xref="GeneID:5318160"
     CDS             complement(1461386..1462336)
                     /locus_tag="Smed_4949"
                     /note="PFAM: ExoV-like protein;
                     KEGG: sme:SMb20949 putative pyruvyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ExoV-like protein"
                     /protein_id="YP_001313664.1"
                     /db_xref="GI:150377068"
                     /db_xref="InterPro:IPR014970"
                     /db_xref="GeneID:5318160"
                     /translation="MKPYYWESQHGNFGDDLNLWLWDFLLPGFREIHPETLLVGVGTV
                     LNRALLPEGTHKLVIGSGFGYGTLPDMSDRQEWDIRSVRGPLTAAKVGVAPELGIIDP
                     AVMVADLPEFQDLGKIYKRSFVPHWESAIAGLWPAICDVVGLNYIDPRGEAKDVIRKI
                     AQSELIVAESMHGAILADAFRVPWTAVSTSNSINSFKWNDWAQTLGVTYRPRRVPVST
                     RAEAVIKGSRFWGMDFEPKEPRPEDPNRRNIDGDVVVAERAPRHSSLRGAAKRVLAAP
                     SALALWHASRATPQLSKDSALAERKERFQVVLEGIRRDYF"
     misc_feature    complement(1461764..>1462204)
                     /locus_tag="Smed_4949"
                     /note="Polysaccharide pyruvyl transferase; Region:
                     PS_pyruv_trans; pfam04230"
                     /db_xref="CDD:217977"
     gene            complement(1462448..1463407)
                     /locus_tag="Smed_4950"
                     /db_xref="GeneID:5318161"
     CDS             complement(1462448..1463407)
                     /locus_tag="Smed_4950"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb21690 glucosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313665.1"
                     /db_xref="GI:150377069"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318161"
                     /translation="MAKLTVVIPYYQKEPGILRRALASVFAQTFEDFHVLIIDDQSPY
                     PVADELVGLTSEQEVRITVVRQPNAGPGGARNTGLDNVPAGSEFVAFLDSDDVWTPDH
                     LLNAYQSMTRFDADCYWASITGGDAFYYHFGVADLEKSEMVTRLSEDPLVVELPELQD
                     VMLKDWSFLHMSCMVIGRKLFETARFEAALKLAAEDVLFFCDCVLAAKRVVLCDAAGA
                     VRGEGLNIFHSIDNDSPQFLKQQFNTWVALDTLEGRYQNRPKAMAAIRSYKHTARRQA
                     LWSQARRIKSRKLPQFDLLARWLWRDPRLLGSAAELAVGKLSR"
     misc_feature    complement(<1463066..1463407)
                     /locus_tag="Smed_4950"
                     /note="Glycosyltransferases involved in cell wall
                     biogenesis [Cell envelope biogenesis, outer membrane];
                     Region: WcaA; COG0463"
                     /db_xref="CDD:223539"
     misc_feature    complement(<1463021..1463392)
                     /locus_tag="Smed_4950"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cd00761"
                     /db_xref="CDD:132997"
     misc_feature    complement(order(1463123..1463125,1463129..1463131,
                     1463294..1463296,1463375..1463377,1463381..1463383))
                     /locus_tag="Smed_4950"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            1463532..1465016
                     /locus_tag="Smed_4951"
                     /db_xref="GeneID:5318162"
     CDS             1463532..1465016
                     /locus_tag="Smed_4951"
                     /note="PFAM: polysaccharide biosynthesis protein;
                     virulence factor MVIN family protein;
                     KEGG: sme:SMb20950 putative transport protein, similar to
                     Wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="YP_001313666.1"
                     /db_xref="GI:150377070"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="InterPro:IPR004268"
                     /db_xref="GeneID:5318162"
                     /translation="MTPTVNAKTVTRNVGWSVLSKTGTFGLKFVTVPILARILSPEEF
                     GAVAVALTVVQFLAMIGGAGLTSALVIQHEEEMETVHSVFWANLAIALMMALGLFVFA
                     EPLATLLGAPEASYLLKIMSLLIPLQLSGDVAYSLLVRRMNFRKDAVWSMISESLGAV
                     IAVLLALLGFGIWSLIAQLFVSALVRLSGLYAVSRYAPRFVFSMQRVVALSRFSFGMM
                     GSEIANFITFQSPMIVISRYLGLSDAGAYSAANRFASIPNQVVLSAVMGVLFPTFGQM
                     MHDRERRSQALMLSTQVTTVLLAPMMFGLWALAEPAMLVLFGRQWAYAWPVLGLLALS
                     KGILTPCSTFIPYLKGVGKGAVLFWWALIRAAATTGAVAYGAINGSLIEAMIWLCIVN
                     TVTLVGYSWVVFRADDTPFLKGLFLSSRPMIAALLMALVVRFMLERFGAHLPNAALQM
                     IAGAAIGGAIYTVLILLTERSLLRRLLDMMRARKSRAALAGAGE"
     misc_feature    1463553..1464881
                     /locus_tag="Smed_4951"
                     /note="Membrane protein involved in the export of
                     O-antigen and teichoic acid [General function prediction
                     only]; Region: RfbX; COG2244"
                     /db_xref="CDD:225153"
     misc_feature    1463559..1464620
                     /locus_tag="Smed_4951"
                     /note="Uncharacterized subfamily of the multidrug and
                     toxic compound extrusion (MATE) proteins; Region:
                     MATE_tuaB_like; cd13127"
                     /db_xref="CDD:240532"
     gene            1465147..1465221
                     /locus_tag="Smed_4952"
                     /pseudo
                     /db_xref="GeneID:5318163"
     gene            1465637..1465894
                     /locus_tag="Smed_4953"
                     /db_xref="GeneID:5318164"
     CDS             1465637..1465894
                     /locus_tag="Smed_4953"
                     /note="KEGG: sme:SMb20952 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313667.1"
                     /db_xref="GI:150377071"
                     /db_xref="GeneID:5318164"
                     /translation="MILEFWILCAIATAVIAAVRGGHSLFWLLIGCILGPIGIVAAIF
                     VPSLKAKDPSVAAKRQGEVDELARPLRETDTKAVSVKSKDH"
     gene            1466362..1467480
                     /locus_tag="Smed_4954"
                     /db_xref="GeneID:5318165"
     CDS             1466362..1467480
                     /locus_tag="Smed_4954"
                     /note="KEGG: sme:SMb20954 succinyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="succinyltransferase"
                     /protein_id="YP_001313668.1"
                     /db_xref="GI:150377072"
                     /db_xref="GeneID:5318165"
                     /translation="MSMDANVSARINLMRILLISGIVFVHVPYNPQWSPFLGNYGMLD
                     WIRVFLGESLFRIGVPCLSAISGYLLFRRGLAGFDYWKTLKTKARTVLLPFLIWSGSF
                     FVVVYAIQYQGLGFGYLPDTISATPRQWLSMAFALEATPVNLPLYFLRDLMLCVLLSP
                     ILALLVSRYPRVTLLALLAYAILPLPNGIFLKKSILFGFSAGIYASLHGVNIKALDRY
                     AGPIAAGFLAIAVAIAVGLYYTGPDFPLWLDMALRLTSIAGIIGSWAISQLLVRTRLG
                     GRLGRGSGLSFWIFCGHYPLLVLFWMIWNRTGLSYYPLFYFTAPLIAIAILVASHNLV
                     QRLAPDLLAVLTGSRTGAKRIPVPAPQGAQAGYSPQQR"
     misc_feature    1466386..>1466877
                     /locus_tag="Smed_4954"
                     /note="Acyltransferase family; Region: Acyl_transf_3;
                     pfam01757"
                     /db_xref="CDD:216682"
     gene            1467486..1468295
                     /locus_tag="Smed_4955"
                     /db_xref="GeneID:5318166"
     CDS             1467486..1468295
                     /locus_tag="Smed_4955"
                     /note="PFAM: glycoside hydrolase family 16;
                     KEGG: sme:SMb20955 endo-beta-1,3-1,4-glycanase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="YP_001313669.1"
                     /db_xref="GI:150377073"
                     /db_xref="InterPro:IPR000757"
                     /db_xref="InterPro:IPR008263"
                     /db_xref="InterPro:IPR008264"
                     /db_xref="GeneID:5318166"
                     /translation="MTNDRYTRIARLAFIATLPFVGLVSAAAAQEGANGTSFKDDFDS
                     LDTRIWYVSDGWNNGGHQNCTWSKKQVKTVDGILELTFQEKKVKDRNFACGEVQTRKR
                     FGYGTYEARIKAADGSGLNSAFFTYIGPADKKPHDEIDFEVLGKNTAKVQINQYVSAT
                     GGNEFLADVPGGANQGFNDYAFVWEKNRIRYYVNGELVHEVTDPAKIPVNAQKIFFSL
                     WGTDTLTDWMGTFSYKEPTKLQVDRVAFTAAGDKCQFAESVACQLERAASE"
     misc_feature    1467486..1468292
                     /locus_tag="Smed_4955"
                     /note="Beta-glucanase/Beta-glucan synthetase [Carbohydrate
                     transport and metabolism]; Region: SKN1; COG2273"
                     /db_xref="CDD:225182"
     sig_peptide     1467486..1467575
                     /locus_tag="Smed_4955"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.850 at
                     residue 30"
     misc_feature    1467597..1468229
                     /locus_tag="Smed_4955"
                     /note="lichenase, member of glycosyl hydrolase family 16;
                     Region: GH16_lichenase; cd02175"
                     /db_xref="CDD:185684"
     misc_feature    order(1467651..1467653,1467657..1467659,1467669..1467671,
                     1467771..1467773,1467777..1467779,1467846..1467848,
                     1467852..1467854,1467858..1467860,1467864..1467866,
                     1467891..1467893,1467897..1467899,1467903..1467905,
                     1467909..1467911,1468128..1468130,1468134..1468136,
                     1468140..1468142)
                     /locus_tag="Smed_4955"
                     /note="active site"
                     /db_xref="CDD:185684"
     misc_feature    order(1467762..1467764,1467846..1467848,1467852..1467854,
                     1467858..1467860,1467897..1467899,1467903..1467905,
                     1467909..1467911,1467939..1467941,1467945..1467947,
                     1467981..1467983,1468134..1468136,1468140..1468142)
                     /locus_tag="Smed_4955"
                     /note="active site"
                     /db_xref="CDD:185684"
     misc_feature    order(1467897..1467899,1467903..1467905,1467909..1467911)
                     /locus_tag="Smed_4955"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:185684"
     gene            1468388..1469596
                     /locus_tag="Smed_4956"
                     /db_xref="GeneID:5318167"
     CDS             1468388..1469596
                     /locus_tag="Smed_4956"
                     /note="KEGG: sme:SMb20956 putative glucosyltransferase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glucosyltransferase"
                     /protein_id="YP_001313670.1"
                     /db_xref="GI:150377074"
                     /db_xref="GeneID:5318167"
                     /translation="MLQILYLAQDLADPAVRRRTLTLVTGGARVTLAGFRRGANPLAA
                     IDGVEPIELGTTADGRFGQRIGAVVRACMSLKSRLAHVPKPDLIIARNLEMLALARRA
                     VAVFGGTVPIVYECLDIHRLMLRQDMVGRTLRAAEGQLGKDVRLLITSSPAFVEHYFR
                     PISSIGAPPMLLENKVLELDGISEPKAAPAVCPAPGAPWKIGWFGALRCRRSLALLAE
                     FSRRMNGRFEVVLRGRPAYSEFEDFDGFVTNEPFMRFAGAYRNPEDLADIYGEVHFTW
                     AIDFFEEGQNSAWLLPNRLYEGCRHGRVPISMKGTETARFLSVRGIGLVLEEADADSL
                     DTVLGSLSPQSYADAAERISRCNPGSWIFSRADCEALVRQLAALTVETRQHVPIVATA
                     GARHNEGGFL"
     gene            1469593..1470585
                     /locus_tag="Smed_4957"
                     /db_xref="GeneID:5318472"
     CDS             1469593..1470585
                     /locus_tag="Smed_4957"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb20957 glucosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313671.1"
                     /db_xref="GI:150377075"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318472"
                     /translation="MNSEELTSTSSLIVIPCLDEASHIEALIEKLRPALTPLNAQIVI
                     ADGGSTDGTRDIARRLATEDPRVLFLDNPKRIQSAAINRAVAELGADSDYLIRIDAHG
                     TYPDDYCERLVEDALATGADSVVVAMQTVGFSTFQKATAFAQNSKLGNGGSKHRTGAV
                     GHWAEHGHHALMRIEAFKAVGGYDESFSHNEDAELDYRLGKAGYRIWMTDRTSMVYYP
                     RAKIVPLFRQYFGYGRGRAKNFLKHRAMPGLRQMVPLAVAPVVFGALLAIVNWMAVLP
                     AGVWAGACLGYGVWMALGQRNPYGPLAAVAAMVMHLAWSAGFWRELLDFRRRVA"
     misc_feature    1469626..1470366
                     /locus_tag="Smed_4957"
                     /note="ExoA is involved in the biosynthesis of
                     succinoglycan; Region: Succinoglycan_BP_ExoA; cd02525"
                     /db_xref="CDD:133016"
     misc_feature    1469629..1470297
                     /locus_tag="Smed_4957"
                     /note="Glycosyltransferase like family 2; Region:
                     Glyco_tranf_2_3; pfam13641"
                     /db_xref="CDD:222281"
     misc_feature    order(1469638..1469640,1469644..1469646,1469893..1469895)
                     /locus_tag="Smed_4957"
                     /note="Ligand binding site; other site"
                     /db_xref="CDD:133016"
     gene            1470585..1471514
                     /locus_tag="Smed_4958"
                     /db_xref="GeneID:5318473"
     CDS             1470585..1471514
                     /locus_tag="Smed_4958"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb20958 glucosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313672.1"
                     /db_xref="GI:150377076"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318473"
                     /translation="MASETLHIDIGVCTYRRPELAETLRSLASMKVPERTDIRVIIAD
                     NDTDPSARGLVEGLRPQMPFEILYVHCPHSNISIARNCCLDNSTGDFLAFLDDDETVS
                     GDWLVRLLDTARGTGAAAVLGPVKAHYAATAPGWMRGGDFHSTLPVWVKGEIRTGYTC
                     NALLKRDAPSLLGRRFKLALGKSGGEDTDFFAGMHQAGGTIAFSPEAWVHEPVPENRA
                     SLAWLAKRRFRSGQTHGRLLAEKSNGLRQAWNVCLACAKSGFCATAALLCFPSAARRY
                     RFVLRGVLHAGVISGLLGLKEIEQYGAREVTSP"
     misc_feature    1470603..1471271
                     /locus_tag="Smed_4958"
                     /note="Glycosyltransferase like family 2; Region:
                     Glyco_tranf_2_3; pfam13641"
                     /db_xref="CDD:222281"
     misc_feature    1470609..1471088
                     /locus_tag="Smed_4958"
                     /note="Glycosyl transferase family 2; Region:
                     Glycos_transf_2; pfam00535"
                     /db_xref="CDD:215980"
     misc_feature    order(1470708..1470710,1470888..1470890,1470894..1470896)
                     /locus_tag="Smed_4958"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            1471511..1472533
                     /locus_tag="Smed_4959"
                     /db_xref="GeneID:5318474"
     CDS             1471511..1472533
                     /locus_tag="Smed_4959"
                     /note="PFAM: glycosyl transferase family 2;
                     KEGG: sme:SMb20959 glucosyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313673.1"
                     /db_xref="GI:150377077"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="GeneID:5318474"
                     /translation="MSAPLSIPDVTFVVAAYNSADTIMRAIESALSQEGVTVEVIVVD
                     DCSTDATPALVAAIRDLRVRLIALDRNRGPGGARNAGIGAARGKWIAVLDSDDTVRPD
                     RLRRMIERADSAGAQIAVDNIDVVSLGGGSLRMFPEAQLARMPQLTLPAFIGSNILFR
                     SEHNFGYMKPVFERRFLENHGLRFDETLRIGEDYILLASALACGGRCAVEPSAGYIYH
                     IREGSISRVLRLEHIDAMIAADEAFLQRFALDAQAQEMQRKRMRGFRQARSFLVLVDQ
                     LKKRSLAGAFKTALADPLALRHLGMPIAARLRRLAARLLHPPSHAPMTAVERSPLGDD
                     PHTSKG"
     misc_feature    1471532..1472200
                     /locus_tag="Smed_4959"
                     /note="Glycosyltransferase like family 2; Region:
                     Glyco_tranf_2_3; pfam13641"
                     /db_xref="CDD:222281"
     misc_feature    1471547..>1471909
                     /locus_tag="Smed_4959"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cd00761"
                     /db_xref="CDD:132997"
     misc_feature    order(1471553..1471555,1471559..1471561,1471637..1471639,
                     1471790..1471792,1471796..1471798)
                     /locus_tag="Smed_4959"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            1472538..1473443
                     /locus_tag="Smed_4960"
                     /db_xref="GeneID:5318475"
     CDS             1472538..1473443
                     /locus_tag="Smed_4960"
                     /note="PFAM: Nucleotidyl transferase;
                     KEGG: sme:SMb20960 UDPglucose pyrophosphorylase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase"
                     /protein_id="YP_001313674.1"
                     /db_xref="GI:150377078"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="GeneID:5318475"
                     /translation="MNHVRTVRKAVIPVAGNGTRFLPATKAVPKEMLTIVDRPVVQYA
                     VDEARQAGIEHIVFVTSRNKQVIEDHFDDAPELISSLSRSGKKAQISELEAMLPAAGS
                     VSFTRQQAPLGLGHAVWCARDLIGDEPFALLLPDMVSFGARGCLAGLMDLYNEAGGNV
                     VGVEQCAPEEASKYGIVGKGETVRHGFAVTEMVEKPAAGKAPSNYYLNGRYILQPEIF
                     SILAHQTRGAGNEIQLTDGMLTLSQSQSFHAHPYEGRTFDCGAKQGFIEANVAFALAR
                     ADIGDLVFESVRDMVLSHESRIRAA"
     misc_feature    1472559..1473359
                     /locus_tag="Smed_4960"
                     /note="Prokaryotic UGPase catalyses the synthesis of
                     UDP-glucose; Region: UGPase_prokaryotic; cd02541"
                     /db_xref="CDD:133021"
     misc_feature    1472559..1473344
                     /locus_tag="Smed_4960"
                     /note="dTDP-glucose pyrophosphorylase [Cell envelope
                     biogenesis, outer membrane]; Region: RfbA; COG1209"
                     /db_xref="CDD:224130"
     misc_feature    order(1472574..1472585,1472625..1472630,1472859..1472861,
                     1472868..1472879,1472937..1472939,1472943..1472948,
                     1473057..1473062,1473117..1473122,1473156..1473158,
                     1473240..1473242)
                     /locus_tag="Smed_4960"
                     /note="active site"
                     /db_xref="CDD:133021"
     misc_feature    order(1472586..1472588,1472595..1472609,1472613..1472621,
                     1472631..1472639,1472643..1472651,1472661..1472663,
                     1472733..1472735,1472739..1472747,1472751..1472753,
                     1472763..1472768,1472853..1472858,1472862..1472864,
                     1472868..1472870,1473054..1473056,1473228..1473230,
                     1473300..1473302,1473318..1473326,1473330..1473338,
                     1473342..1473350,1473357..1473359)
                     /locus_tag="Smed_4960"
                     /note="tetramer interface; other site"
                     /db_xref="CDD:133021"
     gene            1473587..1475953
                     /locus_tag="Smed_4961"
                     /db_xref="GeneID:5318476"
     CDS             1473587..1475953
                     /locus_tag="Smed_4961"
                     /EC_number="2.7.10.2"
                     /note="TIGRFAM: exopolysaccharide transport protein
                     family;
                     PFAM: lipopolysaccharide biosynthesis protein;
                     KEGG: sme:SMb20961 protein tyrosine kinase, MPA1 family,
                     involved in succinoglycan chain-length determination"
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide transport protein family
                     protein"
                     /protein_id="YP_001313675.1"
                     /db_xref="GI:150377079"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005700"
                     /db_xref="GeneID:5318476"
                     /translation="MNRTAPMKQRSVPLSSIMPSEEQSDGFIDLDRLVAAVFRRARLV
                     TAFVVLFIALGAAYLLFATPYYTSMTQILLDENLSKYAEEEPVPVNSQMLDTQIASAV
                     EILKSGELALRVVDKLKLSENETILNPPRSPVDVVKEWLKTATGLFAGGPEVTEAAAR
                     NGRRQKAAAIIQQSLAVERVSRSSVVAVAFRSSDPVLAATIARGYASAYLTDQLNANF
                     EATERASVWLQERLTDLQQRSQAAALEVAHYRAENGLTAARGELMSEQQMADLNSQLI
                     VAQADTASASARYNQYKSIVDQGPENAVKNATISSKEGDNSVIRDLRTRYLTVGKRER
                     EVSDNFGADHPQAVSLRTEQEDVARQIYQELQQLTASYKNEYEVAQSREASLRKSIQG
                     IAGKTSDSSEQLVQLRELEQKAAALKTLYESYLGRYEQATQQQTFPIAKARVISEAGV
                     PVSPSSPKKTMTLALSAVLGLMVGGAYAAFLEFRERTFRLEGDVRSILGHRSFGYVPL
                     LGTRIKKKAQLVHAHFGSVKRADEAVDNTMPFQRLSRIVVDAPRSTFAETFRNAKLAC
                     DQMLAGSESRVIAIASALPDEGKSIIAANFAALLAASGKRTLLIDADIRKPGLTQMIT
                     PAPRTGLVETLTGEATWPAGIKVDQRTKLAILPAGGASHQRHQSNELLASPGMANLIE
                     NARNAFDYVVVDLAALAPVVDAKAFAPLADGILFVVEWGRTPSRLVRDLLNSEPLINS
                     KVLGVILNKTDMNELGKYSDFDGAEKYRHRYGKYYIENSFTDNQNTAA"
     misc_feature    1473659..1475938
                     /locus_tag="Smed_4961"
                     /note="exopolysaccharide transport protein family; Region:
                     eps_transp_fam; TIGR01005"
                     /db_xref="CDD:130078"
     misc_feature    1473737..>1473970
                     /locus_tag="Smed_4961"
                     /note="Chain length determinant protein; Region: Wzz;
                     pfam02706"
                     /db_xref="CDD:217194"
     misc_feature    1474811..1475020
                     /locus_tag="Smed_4961"
                     /note="G-rich domain on putative tyrosine kinase; Region:
                     GNVR; pfam13807"
                     /db_xref="CDD:222392"
     misc_feature    1475315..>1475569
                     /locus_tag="Smed_4961"
                     /note="The Fer4_NifH superfamily contains a variety of
                     proteins which share a common ATP-binding domain.
                     Functionally, proteins in this superfamily use the energy
                     from hydrolysis of NTP to transfer electron or ion;
                     Region: Fer4_NifH; cl17203"
                     /db_xref="CDD:247757"
     gene            complement(1476012..1476812)
                     /locus_tag="Smed_4962"
                     /db_xref="GeneID:5318477"
     CDS             complement(1476012..1476812)
                     /locus_tag="Smed_4962"
                     /EC_number="2.7.4.7"
                     /note="TIGRFAM: phosphomethylpyrimidine kinase;
                     PFAM: Phosphomethylpyrimidine kinase type-1;
                     KEGG: sme:SMb20962 probable phoshomethylpyrimidine kinase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine kinase"
                     /protein_id="YP_001313676.1"
                     /db_xref="GI:150377080"
                     /db_xref="InterPro:IPR004399"
                     /db_xref="InterPro:IPR013749"
                     /db_xref="GeneID:5318477"
                     /translation="MTAIALTIAGSDSGGGAGIQADLKTFSALGVYGASVITAITAQN
                     TKGVSAVEDVSAEIVSAQIDAVFSDLDVGAVKIGMVSRRETIAAIADGLRRFGKLAVV
                     DPVMVATSGDTLLRPDAVAALIDELLPLAIVATPNLAEAALITGRAVAEEEAEMARQA
                     EAIMRSGAHSVLVKGGHLKNDQATDLFFDGQTFVRLPAARVETQNDHGTGCTLSAAIA
                     AGLARGAPLVEAANAAKTYLHAAISASGRLKIGQGRGPVHHFHHWWED"
     misc_feature    complement(1476078..1476803)
                     /locus_tag="Smed_4962"
                     /note="4-amino-5-hydroxymethyl-2-methyl-pyrimidine
                     phosphate kinase (HMPP-kinase) catalyzes two consecutive
                     phosphorylation steps in the thiamine phosphate
                     biosynthesis pathway, leading to the synthesis of vitamin
                     B1. The first step is the phosphorylation of...; Region:
                     HMPP_kinase; cd01169"
                     /db_xref="CDD:238574"
     misc_feature    complement(order(1476615..1476620,1476630..1476632,
                     1476639..1476641,1476648..1476653,1476657..1476659,
                     1476663..1476668,1476681..1476695,1476702..1476704,
                     1476708..1476725,1476732..1476734,1476741..1476746,
                     1476753..1476755,1476765..1476767,1476771..1476776,
                     1476780..1476782,1476801..1476803))
                     /locus_tag="Smed_4962"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238574"
     misc_feature    complement(order(1476180..1476182,1476576..1476578,
                     1476684..1476686,1476747..1476749,1476783..1476785))
                     /locus_tag="Smed_4962"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238574"
     misc_feature    complement(order(1476183..1476185,1476189..1476191,
                     1476291..1476293,1476393..1476395,1476504..1476506))
                     /locus_tag="Smed_4962"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238574"
     misc_binding    complement(1476941..1477043)
                     /note="TPP riboswitch (THI element) as predicted by Rfam
                     (RF00059), score 79.90"
                     /bound_moiety="thiamin/thiaminpyrophosphate"
     gene            1477253..1477912
                     /locus_tag="Smed_4963"
                     /db_xref="GeneID:5318478"
     CDS             1477253..1477912
                     /locus_tag="Smed_4963"
                     /EC_number="1.11.1.7"
                     /note="PFAM: alkyl hydroperoxide reductase/ Thiol specific
                     antioxidant/ Mal allergen; Redoxin domain protein;
                     KEGG: sme:SMb20964 putative anti-oxidant protein, AhpCTSA
                     family"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxidase"
                     /protein_id="YP_001313677.1"
                     /db_xref="GI:150377081"
                     /db_xref="InterPro:IPR000866"
                     /db_xref="InterPro:IPR013740"
                     /db_xref="GeneID:5318478"
                     /translation="MSLRINDTAPDFTAETTQGTINFHEWIGDGWAVLFSHPKNFTPV
                     CTTELGAMAGIEPEFRKRGVKIIGISVDPVESHTKWKNDIKVATGFDVDYPLIGDRDL
                     KVAKLYDMLPAGAGDTSEGRTPADNATVRSVYVIGPDKKIKLILTYPMTTGRNFNEIL
                     RAIDSIQLTARHQVATPANWQQGDDVIITAAVSNEDAVQRFGSFDTVLPYLRKTKQPT
                     A"
     misc_feature    1477253..1477852
                     /locus_tag="Smed_4963"
                     /note="Peroxiredoxin [Posttranslational modification,
                     protein turnover, chaperones]; Region: AhpC; COG0450"
                     /db_xref="CDD:223527"
     misc_feature    1477265..1477897
                     /locus_tag="Smed_4963"
                     /note="Peroxiredoxin (PRX) family, 1-cys PRX subfamily;
                     composed of PRXs containing only one conserved cysteine,
                     which serves as the peroxidatic cysteine. They are
                     homodimeric thiol-specific antioxidant (TSA) proteins that
                     confer a protective role in cells by...; Region: PRX_1cys;
                     cd03016"
                     /db_xref="CDD:239314"
     misc_feature    order(1477265..1477267,1477379..1477381,1477388..1477396,
                     1477403..1477405,1477499..1477501,1477508..1477510,
                     1477577..1477579,1477637..1477639,1477679..1477687,
                     1477691..1477699,1477703..1477720,1477724..1477726,
                     1477733..1477735,1477745..1477750,1477775..1477780,
                     1477784..1477789,1477880..1477882,1477889..1477891)
                     /locus_tag="Smed_4963"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239314"
     misc_feature    order(1477301..1477303,1477463..1477471,1477475..1477480,
                     1477484..1477489,1477493..1477498,1477523..1477525,
                     1477550..1477555,1477583..1477585,1477604..1477606,
                     1477634..1477636,1477823..1477825,1477874..1477876)
                     /locus_tag="Smed_4963"
                     /note="decamer (pentamer of dimers) interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239314"
     misc_feature    order(1477376..1477378,1477385..1477387,1477643..1477645)
                     /locus_tag="Smed_4963"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:239314"
     gene            complement(1478003..1479010)
                     /locus_tag="Smed_4964"
                     /db_xref="GeneID:5318479"
     CDS             complement(1478003..1479010)
                     /locus_tag="Smed_4964"
                     /note="PFAM: beta-lactamase;
                     KEGG: sme:SMb20965 putative exported enzyme, similar to
                     6-aminohexanoate-dimer hydrolase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase"
                     /protein_id="YP_001313678.1"
                     /db_xref="GI:150377082"
                     /db_xref="InterPro:IPR001466"
                     /db_xref="GeneID:5318479"
                     /translation="MIRLVVIFLALLSFLPVAAAQDRSAVATLVTSLATRDELKPLRA
                     VIVAQHGETIAEKGYRGHTTSESTNIKSASKSIISALVGIAIDKGLLDGPEQKIAALL
                     KAELPPQPDPRINEITIGNLLSMQAGLGRMSGPNYGRWVSSRNWVRFALAQPFDDEPG
                     GRMLYSTASTHLLSAILTKVGGKSTLELAREWLAPLEGFRIGAWDRDPQGIYLGGNQM
                     AMSARSLLAFGELYRNRGRTPEGRQVVPADWIELSWQPRTESRFTGDGYGYGWFMRRI
                     GDEAVYYGWGYGGQMLYVVPTLSLTVVMTSDESGPSARNGYRDALHGVLSEIIGVAKA
                     S"
     sig_peptide     complement(1478948..1479010)
                     /locus_tag="Smed_4964"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.552 at
                     residue 21"
     misc_feature    complement(1478024..1478965)
                     /locus_tag="Smed_4964"
                     /note="Beta-lactamase class C and other penicillin binding
                     proteins [Defense mechanisms]; Region: AmpC; COG1680"
                     /db_xref="CDD:224594"
     misc_feature    complement(1478048..1478881)
                     /locus_tag="Smed_4964"
                     /note="Beta-lactamase; Region: Beta-lactamase; pfam00144"
                     /db_xref="CDD:215746"
     gene            complement(1479172..1479723)
                     /locus_tag="Smed_4965"
                     /db_xref="GeneID:5318480"
     CDS             complement(1479172..1479723)
                     /locus_tag="Smed_4965"
                     /note="PFAM: MaoC domain protein dehydratase;
                     KEGG: sme:SMb20978 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="YP_001313679.1"
                     /db_xref="GI:150377083"
                     /db_xref="InterPro:IPR002539"
                     /db_xref="GeneID:5318480"
                     /translation="MDEFMPTVGVSSTHPADMPDDHAALPVWNAENWFYEDWPIGQRI
                     RSLRRTIGESDSHLFNTLVIDIHPYVQDRMFAEREGIFGRRLVAGAFVFSAGLGLVAT
                     NCVNAFSYGYDKLRFIKPVFIGDTIYTIRTNMEKVPRYKDLGLIRASYQVFKNEGELV
                     LYCEHLQTVKYQNPADFVGKTER"
     misc_feature    complement(1479202..1479663)
                     /locus_tag="Smed_4965"
                     /note="Acyl dehydratase [Lipid metabolism]; Region: MaoC;
                     COG2030"
                     /db_xref="CDD:224941"
     misc_feature    complement(order(1479364..1479375,1479457..1479462))
                     /locus_tag="Smed_4965"
                     /note="active site 2 [active]"
                     /db_xref="CDD:239524"
     misc_feature    complement(order(1479391..1479396,1479400..1479402,
                     1479430..1479435,1479442..1479444))
                     /locus_tag="Smed_4965"
                     /note="active site 1 [active]"
                     /db_xref="CDD:239524"
     gene            complement(1479807..1481120)
                     /locus_tag="Smed_4966"
                     /db_xref="GeneID:5318481"
     CDS             complement(1479807..1481120)
                     /locus_tag="Smed_4966"
                     /note="TIGRFAM: TRAP dicarboxylate transporter, DctM
                     subunit;
                     PFAM: TRAP C4-dicarboxylate transport system permease DctM
                     subunit;
                     KEGG: sme:SMb20979 putative large C4-dicarboxylate uptake
                     permease protein, DedA family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctM"
                     /protein_id="YP_001313680.1"
                     /db_xref="GI:150377084"
                     /db_xref="InterPro:IPR004681"
                     /db_xref="InterPro:IPR010656"
                     /db_xref="GeneID:5318481"
                     /translation="MTLLHLAGPSLLVVVLFLLSTPITWAMAIGALAFFLINMDMIPL
                     ANFAQEVAEGTQSVSLLALPLFVLAGCIMNASGITRRLLTLADVLVGHMTGALAQMCT
                     VLGTLLGGLTASANADAAMLAKTLGVEMSERGYSRAFAAVITSSAAIITSLIPPSIGL
                     IVYGFLAETSIGRLFAAGVVPGLLLAAGLMVTTYFIARKRDYKPLRKQRATRAEATRA
                     LIDGLWALSIPVVIFAGTRYGLFTTTEAGAVVVVYVLFVAVFGYREFTVRQIPEVLAE
                     AVRDSAVVMIMICAAAAFGFYLAWEQVPQAMSGWLGEATDNPLLMLLLINVLLIVIGT
                     AIEGSAALIILTPMLIPLIDGVGIDRVHFGIVFITNLTIAGITPPVGGLMYISSMVLK
                     VPMMAYAREVLPYLAMMMALLIVLSMFPQLSLWLPDLVYGTSAVQ"
     sig_peptide     complement(1481040..1481120)
                     /locus_tag="Smed_4966"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.983) with cleavage site probability 0.785 at
                     residue 27"
     misc_feature    complement(1479855..1481057)
                     /locus_tag="Smed_4966"
                     /note="DctM-like transporters; Region: DctM; pfam06808"
                     /db_xref="CDD:219185"
     misc_feature    complement(1479834..1480970)
                     /locus_tag="Smed_4966"
                     /note="TRAP-type C4-dicarboxylate transport system, large
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctQ; COG1593"
                     /db_xref="CDD:224509"
     gene            complement(1481117..1481668)
                     /locus_tag="Smed_4967"
                     /db_xref="GeneID:5318030"
     CDS             complement(1481117..1481668)
                     /locus_tag="Smed_4967"
                     /note="PFAM: Tripartite ATP-independent periplasmic
                     transporter DctQ component;
                     KEGG: sme:SMb20980 putative small C4-dicarboxylate uptake
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite ATP-independent periplasmic
                     transporter DctQ"
                     /protein_id="YP_001313681.1"
                     /db_xref="GI:150377085"
                     /db_xref="InterPro:IPR007387"
                     /db_xref="GeneID:5318030"
                     /translation="MARSVSPSTVRGIMEISRSPEETIPLISLRRADEAVGVVALIVV
                     VFSILWGVASRYVFPQPAFWTYELAMMAFAYLVFFGAVAGVRLGTHAAIDVLVAALPD
                     GWQKAVAWFNYLLLALFFMVMTILFAWQAWTSRHVHTIALDLSRALSYAPLSLASAGM
                     LFQHLIAERPWSVRLHRNPESLI"
     misc_feature    complement(1481126..1481527)
                     /locus_tag="Smed_4967"
                     /note="TRAP-type C4-dicarboxylate transport system, small
                     permease component [Carbohydrate transport and
                     metabolism]; Region: DctM; COG3090"
                     /db_xref="CDD:225632"
     gene            complement(1481710..1482687)
                     /locus_tag="Smed_4968"
                     /db_xref="GeneID:5318031"
     CDS             complement(1481710..1482687)
                     /locus_tag="Smed_4968"
                     /note="PFAM: TRAP dicarboxylate transporter- DctP subunit;
                     KEGG: sme:SMb20981 putative C4-dicarboxylate transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP dicarboxylate transporter subunit DctP"
                     /protein_id="YP_001313682.1"
                     /db_xref="GI:150377086"
                     /db_xref="InterPro:IPR004682"
                     /db_xref="GeneID:5318031"
                     /translation="MKTLIAAAAMAALSFCGIASAQEYSLRFSTSQVNPNEPIIKAMK
                     TYAERVGERSGGRIAITVMTGDQLGAQKKVNEMVMSGASLLSATDYGQLGQFVPDLSI
                     LAGPYVYPDLAATERLFASDLYKELSGKLEARGIKIIMPNGLFGYRHIISNKPVRSPA
                     DLAGVTIRVPSSPIMMATFGNYGARPTELPWGDVYNALQTGVVDAAEGPFGSIAGAKL
                     NETRKVISKTGHQIMFTAWVASSQFFNGLPEDLQKILLEEGRAIASELTQMTLETDDA
                     YAKQLSASGVEIVTDVDIPAFIEASRAAYDKVPNITPGIYEQVQKAMKQ"
     sig_peptide     complement(1482622..1482687)
                     /locus_tag="Smed_4968"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 22"
     misc_feature    complement(1481713..1482651)
                     /locus_tag="Smed_4968"
                     /note="TRAP-type C4-dicarboxylate transport system,
                     periplasmic component [Carbohydrate transport and
                     metabolism]; Region: DctP; COG1638"
                     /db_xref="CDD:224553"
     misc_feature    complement(1481767..1482597)
                     /locus_tag="Smed_4968"
                     /note="Bacterial extracellular solute-binding protein,
                     family 7; Region: SBP_bac_7; cl15441"
                     /db_xref="CDD:210106"
     gene            complement(1483388..1484665)
                     /locus_tag="Smed_4969"
                     /db_xref="GeneID:5318032"
     CDS             complement(1483388..1484665)
                     /locus_tag="Smed_4969"
                     /note="PFAM: Mandelate racemase/muconate lactonizing
                     protein;
                     KEGG: ret:RHE_PE00430 probable mandelate racemase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing protein"
                     /protein_id="YP_001313683.1"
                     /db_xref="GI:150377087"
                     /db_xref="InterPro:IPR001354"
                     /db_xref="InterPro:IPR013342"
                     /db_xref="GeneID:5318032"
                     /translation="MTRITDLRVFDLRFPTSASLDGSDAMNPDPDYSAAYVILDTDRP
                     GLAGHGLTFTIGRGNDVCCMAIQAMRHLVVGQDIGDILKHPGRFWRHLTSDSQLRWIG
                     PEKGAIHLATGAIVNAIWDLLAKDAGKPVWRLVSEMSAEEIADIVDYRYITDVLTRDE
                     AIEILRRAETGKADRIAALEKEGYPCYTTSAGWLGYDDEKLRRLAQEAVDAGFNHIKM
                     KVGRDLADDMRRLRIAREVIGPDRYLMIDANQVWEVGEAIDWVQKLAFAKPFFIEEPT
                     SPDDVAGHRKIREAIGPVKVATGEMCQNRIMFKQFIAEGAIDIVQIDSCRMGGLNEVL
                     AVLLIAAKYGLPVWPHAGGVGLCEYVQHLSMIDYVAVSGTKDGRVIEYVDHLHEHFLD
                     PCVISDAAYMPPSRPGFSIEMKEKSIEDYTFRG"
     misc_feature    complement(1483391..1484662)
                     /locus_tag="Smed_4969"
                     /note="L-alanine-DL-glutamate epimerase and related
                     enzymes of enolase superfamily [Cell envelope biogenesis,
                     outer membrane / General function prediction only];
                     Region: COG4948"
                     /db_xref="CDD:227284"
     misc_feature    complement(1483424..1484662)
                     /locus_tag="Smed_4969"
                     /note="Human rTS beta is encoded by the rTS gene which,
                     through alternative RNA splicing, also encodes rTS alpha
                     whose mRNA is complementary to thymidylate synthase mRNA.
                     rTS beta expression is associated with the production of
                     small molecules that appear to...; Region:
                     rTSbeta_L-fuconate_dehydratase; cd03324"
                     /db_xref="CDD:239440"
     misc_feature    complement(order(1483523..1483525,1483616..1483618,
                     1483697..1483699,1483766..1483768,1483847..1483849,
                     1483853..1483855,1483925..1483927,1484009..1484011,
                     1484015..1484017,1484105..1484107))
                     /locus_tag="Smed_4969"
                     /note="putative active site pocket [active]"
                     /db_xref="CDD:239440"
     misc_feature    complement(order(1483766..1483768,1483847..1483849,
                     1483925..1483927))
                     /locus_tag="Smed_4969"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:239440"
     gene            complement(1484747..1485592)
                     /locus_tag="Smed_4970"
                     /db_xref="GeneID:5318033"
     CDS             complement(1484747..1485592)
                     /locus_tag="Smed_4970"
                     /EC_number="4.1.1.68"
                     /note="PFAM: fumarylacetoacetate (FAA) hydrolase;
                     KEGG: sme:SMb21112 putative bifunctional enzyme
                     2-hydroxyhepta-2,4-diene-1,7-dioatesomerase
                     5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioatedecarboxylase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxopent-3-ene-1,2,5-tricarboxylate
                     decarboxylase"
                     /protein_id="YP_001313684.1"
                     /db_xref="GI:150377088"
                     /db_xref="InterPro:IPR002529"
                     /db_xref="GeneID:5318033"
                     /translation="MKFLRYGEPGQEKPGLLGSDGIIRDLSGQVPDLAAGALDPSKLT
                     ELAKLDVEALPAVNGNPRLGPCVAGTGKFICIGLNYSDHAAETGATVPPEPIIFMKAT
                     SAIVGPNDDLILPRGSEKTDWEVELGIVIGRTAKYVSEAEALDYVAGYCTVHDVSERA
                     FQTERHGQWTKGKSCDTFGPTGPWLVTKDEVEDPQNLAMWLKVNGETMQDGSTKTMVY
                     GVAYLVSYLSQFMSLHPGDVISTGTPPGVGMGMKPPRYLKAGDVVELGIEGLGSQKQR
                     VRADD"
     misc_feature    complement(1484750..1485565)
                     /locus_tag="Smed_4970"
                     /note="2-keto-4-pentenoate
                     hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase
                     (catechol pathway) [Secondary metabolites biosynthesis,
                     transport, and catabolism]; Region: MhpD; COG0179"
                     /db_xref="CDD:223257"
     misc_feature    complement(1484759..1485379)
                     /locus_tag="Smed_4970"
                     /note="Fumarylacetoacetate (FAA) hydrolase family; Region:
                     FAA_hydrolase; pfam01557"
                     /db_xref="CDD:216570"
     gene            complement(1485615..1486349)
                     /locus_tag="Smed_4971"
                     /db_xref="GeneID:5318034"
     CDS             complement(1485615..1486349)
                     /locus_tag="Smed_4971"
                     /note="PFAM: NAD-dependent epimerase/dehydratase;
                     short-chain dehydrogenase/reductase SDR;
                     KEGG: sme:SMb21111 putative oxidoreductase, red
                     superfamily protein"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="YP_001313685.1"
                     /db_xref="GI:150377089"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR002424"
                     /db_xref="GeneID:5318034"
                     /translation="MTANLAGKVVLVTAAAQGIGRATALAFARAGAKVHATDINTDAL
                     GSFGGEAGISTHRLDVLDTAAVEALITETGAVDVLFNCAGFVHAGSVLTMKDEDLDFA
                     FDLNVKSMIRTIRAVLPGMIARKDGSIINMASVASSIKGVPNRFAYGVTKAAVIGLTK
                     AVAADYVGDGIRCNAICPGTVESPSLESRMRAQGDYETARAAFISRQPMGRLGTPEEI
                     ADLAVYLAGATYTSGQAYAIDGGWTI"
     misc_feature    complement(1485624..1486340)
                     /locus_tag="Smed_4971"
                     /note="3-ketoacyl-(acyl-carrier-protein) reductase;
                     Validated; Region: fabG; PRK05653"
                     /db_xref="CDD:235546"
     misc_feature    complement(1485618..1486334)
                     /locus_tag="Smed_4971"
                     /note="human DHRS6-like, classical (c) SDRs; Region:
                     DHRS6_like_SDR_c; cd05368"
                     /db_xref="CDD:187626"
     misc_feature    complement(order(1485783..1485785,1485795..1485803,
                     1485807..1485818,1485894..1485896,1485906..1485908,
                     1485951..1485956,1486035..1486037,1486098..1486106,
                     1486170..1486178,1486230..1486238,1486293..1486304,
                     1486308..1486310))
                     /locus_tag="Smed_4971"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187626"
     misc_feature    complement(order(1485618..1485620,1485627..1485641,
                     1485648..1485650,1485654..1485662,1485678..1485680,
                     1485687..1485689,1485699..1485701,1485711..1485719,
                     1485723..1485728,1485810..1485812,1485849..1485863,
                     1485867..1485872,1485876..1485884,1485888..1485893,
                     1485900..1485905,1485912..1485914,1485918..1485923,
                     1485927..1485935,1485939..1485941,1485984..1485986,
                     1485993..1485998,1486005..1486010,1486017..1486019,
                     1486026..1486031,1486041..1486043,1486050..1486055,
                     1486062..1486070,1486074..1486082,1486161..1486163))
                     /locus_tag="Smed_4971"
                     /note="homotetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187626"
     misc_feature    complement(order(1485852..1485860,1485867..1485872,
                     1485876..1485884,1485888..1485893,1485900..1485905,
                     1485912..1485914,1485918..1485923,1485927..1485929,
                     1485933..1485935,1485939..1485941,1485984..1485986,
                     1485993..1485998,1486005..1486010,1486017..1486019,
                     1486026..1486031,1486041..1486043,1486050..1486055,
                     1486062..1486070,1486074..1486082,1486161..1486163))
                     /locus_tag="Smed_4971"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187626"
     misc_feature    complement(order(1485894..1485896,1485906..1485908,
                     1485948..1485950,1486032..1486034))
                     /locus_tag="Smed_4971"
                     /note="active site"
                     /db_xref="CDD:187626"
     gene            complement(1486346..1486807)
                     /locus_tag="Smed_4972"
                     /db_xref="GeneID:5318035"
     CDS             complement(1486346..1486807)
                     /locus_tag="Smed_4972"
                     /note="PFAM: MaoC domain protein dehydratase;
                     KEGG: sme:SMb21110 putative MaoC-like (monoamine
                     oxidase-like) protein, similar to NodN"
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="YP_001313686.1"
                     /db_xref="GI:150377090"
                     /db_xref="InterPro:IPR002539"
                     /db_xref="GeneID:5318035"
                     /translation="MSEQTIYFEDYIQGHVRLTSGRTITETDFVVHAGHTGDFFPHHM
                     DSEFAKTLPGGQRIAHGTMIFSIGVGLTASLINPVAFSYGYDRLRFVRPVHIGDTIRT
                     RVTIAAKEDDPKRPAAGRVVERCEVINQRGEVVLAADHILIVERKSEGTIQ"
     misc_feature    complement(1486376..1486789)
                     /locus_tag="Smed_4972"
                     /note="The hotdog fold was initially identified in the E.
                     coli FabA (beta-hydroxydecanoyl-acyl carrier protein
                     (ACP)-dehydratase) structure and subsequently in 4HBT
                     (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A
                     number of other seemingly unrelated...; Region: hot_dog;
                     cl00509"
                     /db_xref="CDD:241913"
     misc_feature    complement(order(1486529..1486540,1486625..1486630))
                     /locus_tag="Smed_4972"
                     /note="active site 2 [active]"
                     /db_xref="CDD:239524"
     misc_feature    complement(order(1486556..1486561,1486565..1486567,
                     1486589..1486591,1486598..1486603,1486610..1486612))
                     /locus_tag="Smed_4972"
                     /note="active site 1 [active]"
                     /db_xref="CDD:239524"
     gene            complement(1486810..1487892)
                     /locus_tag="Smed_4973"
                     /db_xref="GeneID:5318036"
     CDS             complement(1486810..1487892)
                     /locus_tag="Smed_4973"
                     /note="PFAM: oxidoreductase domain protein;
                     KEGG: sme:SMb21109 putative oxidoreductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase domain-containing protein"
                     /protein_id="YP_001313687.1"
                     /db_xref="GI:150377091"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="GeneID:5318036"
                     /translation="MTEAFIPSSLRQWWPKPANPRPIVIFGAGSIVGDAHLPAYRKAG
                     FPVAGIFDPDGEKAAALAQQWDIRAFATEEEAVAAENAVFDLATPPAAHVPILSKLPE
                     GSFALIQKPMGGNLAAATDILEICRARQIKAAVNFQLRFAPMMIALKDAIARGYLGEV
                     VDFDAWLALATPWGLWPFLKGLPRIEIAMHSIHYLDLVRDLLGDPQGVHAKSIGHPNH
                     DVAQTRTAAILDYGERVRCVLSVNHDHGYGRKFQACEFRISGTRGAAYVKLGVNLDYP
                     RGEPDELWIRPSDCSEWVPVPLEGSWFPDAFANRMANIQRHASGDDDELIGSVEDAWR
                     TMALVEAAYQSSARPATPIPALSTEK"
     misc_feature    complement(1486840..1487826)
                     /locus_tag="Smed_4973"
                     /note="Predicted dehydrogenases and related proteins
                     [General function prediction only]; Region: MviM; COG0673"
                     /db_xref="CDD:223745"
     misc_feature    complement(1487482..1487826)
                     /locus_tag="Smed_4973"
                     /note="Oxidoreductase family, NAD-binding Rossmann fold;
                     Region: GFO_IDH_MocA; pfam01408"
                     /db_xref="CDD:201778"
     gene            complement(1487885..1488214)
                     /locus_tag="Smed_4974"
                     /db_xref="GeneID:5318037"
     CDS             complement(1487885..1488214)
                     /locus_tag="Smed_4974"
                     /note="PFAM: protein of unknown function DUF718;
                     KEGG: sme:SMb21108 conserved hypothetical protein, similar
                     to Y03002"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313688.1"
                     /db_xref="GI:150377092"
                     /db_xref="InterPro:IPR008000"
                     /db_xref="GeneID:5318037"
                     /translation="MQRMGMVIGLESAKLAEYKRLHAAVWPDILALISECNITNYSIF
                     LKEPENLLFGYWEYVGQDFDADMAKMAAHPKNQEWWSVCMPCQKPLVTRKEGEWWAMM
                     EEVFHHD"
     misc_feature    complement(1487888..1488214)
                     /locus_tag="Smed_4974"
                     /note="Uncharacterized conserved protein [Function
                     unknown]; Region: COG3254"
                     /db_xref="CDD:225793"
     gene            complement(1488227..1489339)
                     /locus_tag="Smed_4975"
                     /db_xref="GeneID:5318038"
     CDS             complement(1488227..1489339)
                     /locus_tag="Smed_4975"
                     /note="PFAM: Mandelate racemase/muconate lactonizing
                     protein;
                     KEGG: sme:SMb21107 putative mandelate racemase or
                     evolutionary related enzyme of the mandelate racemase
                     muconate lactonizing enzyme family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing protein"
                     /protein_id="YP_001313689.1"
                     /db_xref="GI:150377093"
                     /db_xref="InterPro:IPR001354"
                     /db_xref="InterPro:IPR013341"
                     /db_xref="InterPro:IPR013342"
                     /db_xref="GeneID:5318038"
                     /translation="MARIERIELRMVDLPPKVKRTDAIQSFVSQETPIVTITDSDGAA
                     GTGYSYTIGTGGSSVMRLLSDHLVPMLIGEDADCIEALWHKMEFATHATTIGAITALA
                     LAAVDTALWDLRARKQKLPLWKLAGGAKESCPLYTTEGGWLHIEKQALVEDALQAKAK
                     GFSGSKVKIGKPSGAEDYDRLAAMRAALGDGFEIMTDCNQGFTVDEAIRRAARLRELD
                     LAWIEEPLPADDLDGHIRLTRSTSTPIAVGESIYSIRHFREYMQKGACSIVQVDVARI
                     GGITPWLKVAHAAEAFDIPVCPHFLMELHVSLVCAVPNGKYVEYIPQLDDLTQKGMEI
                     REGRAIAPSDPGIGIAWDWEAVKARSVAEFTREFRR"
     misc_feature    complement(1488245..1489339)
                     /locus_tag="Smed_4975"
                     /note="L-alanine-DL-glutamate epimerase and related
                     enzymes of enolase superfamily [Cell envelope biogenesis,
                     outer membrane / General function prediction only];
                     Region: COG4948"
                     /db_xref="CDD:227284"
     misc_feature    complement(1488293..1489333)
                     /locus_tag="Smed_4975"
                     /note="Mandelate racemase (MR)-like subfamily of the
                     enolase superfamily. Enzymes of this subgroup share three
                     conserved carboxylate ligands for the essential divalent
                     metal ion (usually Mg2+), two aspartates and a glutamate,
                     and conserved catalytic residues; Region: MR_like;
                     cd03316"
                     /db_xref="CDD:239432"
     misc_feature    complement(order(1488383..1488385,1488443..1488445,
                     1488524..1488526,1488593..1488595,1488671..1488673,
                     1488749..1488751,1488836..1488838,1488842..1488844))
                     /locus_tag="Smed_4975"
                     /note="active site pocket [active]"
                     /db_xref="CDD:239432"
     gene            complement(1489341..1490438)
                     /locus_tag="Smed_4976"
                     /db_xref="GeneID:5318039"
     CDS             complement(1489341..1490438)
                     /locus_tag="Smed_4976"
                     /note="PFAM: ABC transporter related; Transport-associated
                     OB domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21106 putative sugar uptake ABC transporter
                     ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313690.1"
                     /db_xref="GI:150377094"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013611"
                     /db_xref="GeneID:5318039"
                     /translation="MAPVTLRKLVKRYGALEVVHGIDLEVKDREFIALVGPSGCGKST
                     TLRMIAGLEEVSGGAIEIGGRKVNDLPPRARNISMVFQSYALYPHMTVAENMGFSLKI
                     AGRSADEIKTRVDEAAAILDLGHLLERRPSQLSGGQRQRVAMGRAIVRQPDVFLFDEP
                     LSNLDAKLRTQVRTEIKKLHARMQATMIYVTHDQVEAMTLSDRIVIMRDGHIEQVGTP
                     EDVFRRPATKFVAGFIGSPPMNMEEAVLTDGKLAFTTGASLPVPPRFRSSLREGQKVT
                     FGLRPDDIYPSGHGLHAGDADAVHELELPVTITEPLGNETLVFTQFNGRDWVSRMLNP
                     RPLRSGEKVRMSLDLSRAHLFDGETGKALAG"
     misc_feature    complement(1489356..1490438)
                     /locus_tag="Smed_4976"
                     /note="glycerol-3-phosphate transporter ATP-binding
                     subunit; Provisional; Region: ugpC; PRK11650"
                     /db_xref="CDD:236947"
     misc_feature    complement(1489791..1490429)
                     /locus_tag="Smed_4976"
                     /note="The N-terminal ATPase domain of the maltose
                     transporter, MalK; Region: ABC_MalK_N; cd03301"
                     /db_xref="CDD:213268"
     misc_feature    complement(1490310..1490333)
                     /locus_tag="Smed_4976"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(order(1489863..1489865,1489962..1489967,
                     1490193..1490195,1490307..1490315,1490319..1490324))
                     /locus_tag="Smed_4976"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1490193..1490204)
                     /locus_tag="Smed_4976"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1490010..1490039)
                     /locus_tag="Smed_4976"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1489962..1489979)
                     /locus_tag="Smed_4976"
                     /note="Walker B; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1489944..1489955)
                     /locus_tag="Smed_4976"
                     /note="D-loop; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1489857..1489877)
                     /locus_tag="Smed_4976"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213268"
     misc_feature    complement(1489374..1489607)
                     /locus_tag="Smed_4976"
                     /note="TOBE domain; Region: TOBE_2; pfam08402"
                     /db_xref="CDD:219823"
     gene            complement(1490445..1491311)
                     /locus_tag="Smed_4977"
                     /db_xref="GeneID:5318040"
     CDS             complement(1490445..1491311)
                     /locus_tag="Smed_4977"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21105 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313691.1"
                     /db_xref="GI:150377095"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318040"
                     /translation="MDTNASHRLRRRLLKAAHFVGLFLAMAVICLPGLWIVLSSLRPT
                     VEIMAKPPVWIPETLSLDAYRAMFSGAGQGGVPVWDYFRNSLIVSVTSTVIALAIGLS
                     GGYAFARYRFKAKSAIFLGFMLTRAVPGIALSLPLFMLYARTGIIDTHFSLILTYVAL
                     NVPFTIWLIDGFFRQVPKDLAEAAQIDGCTPWQAFWQVEFPLAGPGIASAGIFAFLTS
                     WNEYALASQITRSVNSKTLPVGLLDYTAEFTIDWRGMCALAVVMIVPALTLTFIIQKH
                     LVSGLTFGAVKG"
     misc_feature    complement(1490451..1491269)
                     /locus_tag="Smed_4977"
                     /note="ABC-type sugar transport system, permease component
                     [Carbohydrate transport and metabolism]; Region: UgpE;
                     COG0395"
                     /db_xref="CDD:223472"
     misc_feature    complement(1490511..1491068)
                     /locus_tag="Smed_4977"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1490511..1490516,1490523..1490528,
                     1490535..1490540,1490544..1490549,1490556..1490561,
                     1490589..1490594,1490631..1490636,1490643..1490654,
                     1490673..1490675,1490682..1490687,1490727..1490729,
                     1490778..1490780,1490787..1490792,1490802..1490804,
                     1490808..1490813,1490820..1490822,1490826..1490828,
                     1490898..1490900,1490904..1490909,1490916..1490945,
                     1490949..1490960,1490988..1490990,1491003..1491008,
                     1491015..1491020))
                     /locus_tag="Smed_4977"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1490637..1490654,1490898..1490942))
                     /locus_tag="Smed_4977"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1490559..1490561,1490589..1490591,
                     1490598..1490600,1490634..1490636,1490838..1490840,
                     1490898..1490900))
                     /locus_tag="Smed_4977"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1490706..1490708,1490718..1490723,
                     1490739..1490777))
                     /locus_tag="Smed_4977"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1491311..1492207)
                     /locus_tag="Smed_4978"
                     /db_xref="GeneID:5318791"
     CDS             complement(1491311..1492207)
                     /locus_tag="Smed_4978"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21104 putative sugar uptake ABC transporter
                     permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313692.1"
                     /db_xref="GI:150377096"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5318791"
                     /translation="MKLSKLSAPTLLLLPAFIVLAVFIVLPLMFSLYSSFTPFRLTKP
                     DTLWVFIGFRNYVNVLTNAEFWVAFGRTVLLLTIALNAEMLLGLGLALLVNKATRGQR
                     ILRTAMMFPMMFSPVLVGFQFKFLFNDNIGFVNNALQSLGLSDRAIPWLIDGNLALFS
                     IIVAEVWSSTAVFAILILAGLLAMPKDPVEAAHVDGCTPWQTFRYVTWPYLMPFAFIA
                     MTIRSLDVARAYDIVKIMTDGGPAKRTELLWTLVGRTAYGDARMGLANAMAYVAILLS
                     IVFTVYFFRKLAAARQQIGAEW"
     sig_peptide     complement(1492142..1492207)
                     /locus_tag="Smed_4978"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.996) with cleavage site probability 0.869 at
                     residue 22"
     misc_feature    complement(1491329..1492159)
                     /locus_tag="Smed_4978"
                     /note="ABC-type spermidine/putrescine transport system,
                     permease component II [Amino acid transport and
                     metabolism]; Region: PotC; COG1177"
                     /db_xref="CDD:224098"
     misc_feature    complement(1491377..1491922)
                     /locus_tag="Smed_4978"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1491377..1491382,1491389..1491394,
                     1491401..1491406,1491410..1491415,1491422..1491424,
                     1491431..1491433,1491461..1491466,1491503..1491508,
                     1491515..1491526,1491545..1491547,1491554..1491559,
                     1491599..1491601,1491650..1491652,1491659..1491664,
                     1491674..1491676,1491680..1491685,1491692..1491694,
                     1491698..1491700,1491707..1491712,1491836..1491838,
                     1491842..1491847,1491854..1491883,1491887..1491898))
                     /locus_tag="Smed_4978"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1491509..1491526,1491836..1491880))
                     /locus_tag="Smed_4978"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1491431..1491433,1491461..1491463,
                     1491470..1491472,1491506..1491508,1491725..1491727,
                     1491836..1491838))
                     /locus_tag="Smed_4978"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1491578..1491580,1491590..1491595,
                     1491611..1491649))
                     /locus_tag="Smed_4978"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1492278..1493597)
                     /locus_tag="Smed_4979"
                     /db_xref="GeneID:5318792"
     CDS             complement(1492278..1493597)
                     /locus_tag="Smed_4979"
                     /note="PFAM: extracellular solute-binding protein family
                     1;
                     KEGG: sme:SMb21103 putative sugar uptake ABC transporter
                     periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313693.1"
                     /db_xref="GI:150377097"
                     /db_xref="InterPro:IPR006059"
                     /db_xref="GeneID:5318792"
                     /translation="MNRLLSGVSAGVIMLVCAMGAASAADLPGKFEGVTIDAKLIGGQ
                     QYEKLYERIGEWEKATGAKVNILSKKNHFELDKEIKSDIATGGITWCIGSNHSSFAPQ
                     YPDIYADLFGLVPSEEVARFVPAVIDASTLEGKLVMLPRAQFDVSALYYQKSLYQDEA
                     KKAEFKAKYGYDLAPPDTWAQVSDQAEFFAAPPNFYGTQFAGKEEAINGRFYEMLVAE
                     GGEYLDKDGRPAFNSEAGVRALDWFVKLYKSKAVPPGTTNYLWDDLGQGFASGSIAVN
                     LDWPGWASFFNDPKSSKVAGNVGVKVQPAGSSGKRTGWSGHHGFSVTESCGSKEAAAS
                     LVWWLTNEDSQMLESAAGPLPTRSAVWDHNIKAAEGDAYKTEVLQAFQEAAKHAFPVP
                     QTAEWIEISNAVYPELQAAILGDKTSKEALDAAAEKATGILEDAGKL"
     sig_peptide     complement(1493523..1493597)
                     /locus_tag="Smed_4979"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.996 at
                     residue 25"
     misc_feature    complement(1492296..1493576)
                     /locus_tag="Smed_4979"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     misc_feature    complement(1492560..>1493066)
                     /locus_tag="Smed_4979"
                     /note="Bacterial extracellular solute-binding protein;
                     Region: SBP_bac_1; pfam01547"
                     /db_xref="CDD:216563"
     gene            1493765..1494547
                     /locus_tag="Smed_4980"
                     /db_xref="GeneID:5318793"
     CDS             1493765..1494547
                     /locus_tag="Smed_4980"
                     /note="PFAM: regulatory protein IclR; Transcriptional
                     regulator IclR;
                     KEGG: sme:SMb21102 putative transcriptional regulator
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein IclR"
                     /protein_id="YP_001313694.1"
                     /db_xref="GI:150377098"
                     /db_xref="InterPro:IPR005471"
                     /db_xref="InterPro:IPR014757"
                     /db_xref="GeneID:5318793"
                     /translation="MDSEESDKYRAPALDKGLDILELLASVDGGLTQAEISKRLNRSP
                     NEFYRMLDRLVRRGYVTRIDGDLYSLTLKLFGLAQLHAPVRRLVSFATPLMRELAQRS
                     KQANQLAVFDRGSAVVIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEEREM
                     MISEHVRSRDEINLTPEFYARLDQIRERGYEMMASAQTAGVYNLSAPILSSDGRSLAA
                     LTCPYISLVNNPSAPDITETISLLLKTASQLSALAGADVAQG"
     misc_feature    1493798..1494529
                     /locus_tag="Smed_4980"
                     /note="Transcriptional regulator [Transcription]; Region:
                     IclR; COG1414"
                     /db_xref="CDD:224332"
     misc_feature    1493798..1494061
                     /locus_tag="Smed_4980"
                     /note="IclR helix-turn-helix domain; Region: HTH_IclR;
                     cl17605"
                     /db_xref="CDD:248159"
     misc_feature    1494158..1494514
                     /locus_tag="Smed_4980"
                     /note="Bacterial transcriptional regulator; Region: IclR;
                     pfam01614"
                     /db_xref="CDD:201890"
     gene            1494610..1495446
                     /locus_tag="Smed_4981"
                     /db_xref="GeneID:5318794"
     CDS             1494610..1495446
                     /locus_tag="Smed_4981"
                     /note="PFAM: amidohydrolase 2;
                     KEGG: sme:SMb21101 conserved hypothetical
                     membrane-anchored protein"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase 2"
                     /protein_id="YP_001313695.1"
                     /db_xref="GI:150377099"
                     /db_xref="InterPro:IPR006992"
                     /db_xref="GeneID:5318794"
                     /translation="MIIDTHLHLIDKSALSYPWLGGVPALDRDFLYSAYAAEAKRVGI
                     AASLHMEVDVEAGQIERETSEIARLSREPGSLLRGAIAACRPEDDGFAAYLERQEANA
                     FVRGFRRVLHVVADDLSEQPLFRENIRRLSATRFTFDLCVLPHQIPKATALADLAPEV
                     RFVLDHCGVPDIKGRAEHPWREHMTEIARRPNVTAKISGVIAYAEEDWTLASIRPYVE
                     HTIAAFGWDRIVWGSDWPVCTLGGNLSTWVAATHALIEGCSLDERTKLLSGNARRIWN
                     LG"
     misc_feature    1494610..1495443
                     /locus_tag="Smed_4981"
                     /note="Predicted metal-dependent hydrolase of the
                     TIM-barrel fold [General function prediction only];
                     Region: COG3618"
                     /db_xref="CDD:226145"
     misc_feature    1494616..1495440
                     /locus_tag="Smed_4981"
                     /note="Amidohydrolase; Region: Amidohydro_2; pfam04909"
                     /db_xref="CDD:218322"
     gene            complement(1495538..1496416)
                     /locus_tag="Smed_4982"
                     /db_xref="GeneID:5318795"
     CDS             complement(1495538..1496416)
                     /locus_tag="Smed_4982"
                     /note="PFAM: polysaccharide deacetylase;
                     KEGG: sme:SMb21100 putative saccharide deacetylase,
                     slightly similar to NodB protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="YP_001313696.1"
                     /db_xref="GI:150377100"
                     /db_xref="InterPro:IPR002509"
                     /db_xref="GeneID:5318795"
                     /translation="MTYDLTPRPLNKAPRTPAMTWPNGARSAVFIGFDVDAETAWIGN
                     SPSNIDRMVTTSHGGYDARVGIARIVGLMDELGLKATFFTPGWTALAHPEACETILRA
                     GHEIGHHGYLHKMPDRDRLDETFEEIDRGFDALQRVFGKRPVGYRAPSGENFPELIAY
                     LARSGIRYSSSFRDDILPYRHAASDGMPGPVEIPINFAFDDWNFGMSSRASPRPLFGR
                     EAVLSLWIDEFEATHAWGGVTTLVLHPQVSGRPMRWHLLRDFLRHVQEKGDVWIATGE
                     EITNHFEALERHRGAS"
     misc_feature    complement(1495565..1496401)
                     /locus_tag="Smed_4982"
                     /note="putative urate catabolism protein; Region:
                     uraD_N-term-dom; TIGR03212"
                     /db_xref="CDD:211797"
     misc_feature    complement(1495571..1496335)
                     /locus_tag="Smed_4982"
                     /note="Catalytic domain of Helicobacter pylori
                     peptidoglycan deacetylase (HpPgdA) and similar proteins;
                     Region: CE4_HpPgdA_like; cd10938"
                     /db_xref="CDD:200563"
     misc_feature    complement(order(1495685..1495687,1496078..1496080,
                     1496090..1496092,1496309..1496311,1496315..1496317))
                     /locus_tag="Smed_4982"
                     /note="active site"
                     /db_xref="CDD:200563"
     misc_feature    complement(order(1495685..1495687,1496309..1496311))
                     /locus_tag="Smed_4982"
                     /note="catalytic site [active]"
                     /db_xref="CDD:200563"
     misc_feature    complement(order(1496078..1496080,1496090..1496092,
                     1496309..1496311))
                     /locus_tag="Smed_4982"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:200563"
     misc_feature    complement(order(1495643..1495645,1495652..1495657,
                     1495661..1495669,1495724..1495726,1495733..1495738,
                     1495745..1495750,1495790..1495798,1495802..1495810,
                     1495823..1495831,1495886..1495906,1495958..1495960,
                     1495964..1495969,1496027..1496029,1496036..1496041,
                     1496048..1496053,1496060..1496065,1496072..1496077,
                     1496081..1496086,1496141..1496149,1496156..1496158,
                     1496213..1496215,1496225..1496227,1496237..1496242,
                     1496246..1496254,1496258..1496263,1496288..1496293))
                     /locus_tag="Smed_4982"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:200563"
     gene            complement(1496427..1497887)
                     /locus_tag="Smed_4983"
                     /db_xref="GeneID:5318796"
     CDS             complement(1496427..1497887)
                     /locus_tag="Smed_4983"
                     /note="PFAM: MmgE/PrpD family protein;
                     KEGG: bam:Bamb_6463 MmgE/PrpD family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="MmgE/PrpD family protein"
                     /protein_id="YP_001313697.1"
                     /db_xref="GI:150377101"
                     /db_xref="InterPro:IPR005656"
                     /db_xref="GeneID:5318796"
                     /translation="MAPAELPGPPPRLSLRDKKMSSSMSRVQAHAPVDRLAYFVSKIS
                     FETLPDDVVEKTKVHVADTIGAALAGACSAEAAIARRTAGTPGGALIWGTGGRTSARD
                     AALVNGVAAHALELDDSGGCDHSGAVVIPAVLAAISEVPGPVSGRELIASVVAGYEVG
                     RRVLEAAGGYDSHNGLGWHSTGTCGALAAAAAVARLSGFGSLATRDAITLATSFSSGL
                     WAFIHDGSQAKKVHAGRAAEGGLLAARLAGEGLAGPSRVFEDVWGGFFRAFNKDACEP
                     QNLCEGLGESWKVKRAVLKPYASCRGAHSAVDALDDLLSESGRDAAAIDRIELRLSAM
                     LMGMCGARESGAMAAAQMSLPYALAARCVFGTAGLASYAADRRADPRVQAVMDGMLLE
                     VDDTMQPLDEPIVTLLFKDGTRVSKTVPRATGSAERPMQPAAIHAKFDALAAMSIEPE
                     QADRLWRMLAEIENLNDCRALEALLAGDGDRRPVFC"
     misc_feature    complement(1496490..1497797)
                     /locus_tag="Smed_4983"
                     /note="Uncharacterized protein involved in propionate
                     catabolism [General function prediction only]; Region:
                     PrpD; COG2079"
                     /db_xref="CDD:224990"
     gene            complement(1497900..1498730)
                     /locus_tag="Smed_4984"
                     /db_xref="GeneID:5318797"
     CDS             complement(1497900..1498730)
                     /locus_tag="Smed_4984"
                     /note="PFAM: extracellular solute-binding protein family
                     3;
                     KEGG: sme:SMb21097 putative amino acid uptake ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313698.1"
                     /db_xref="GI:150377102"
                     /db_xref="InterPro:IPR001638"
                     /db_xref="GeneID:5318797"
                     /translation="MNKHIAALTVACLAATSASAAGLPERIKTAGKVVAANQPNYPPM
                     EYVDPATNELKGVDIDLGLALAKELGTTVEWTNIGFEQMISSLTTGRVDLIHSGMSDL
                     PKRRETLDFVDYMKSGAQFYTSFGRKDEFKTLTDFCGKTVGMSRRTSFPDETAKWSAA
                     NCEAKGLGAIKVVGTEGSADARAQLKQGRLDAAVQGSETLPYLMDLEKDTYAVVGEPF
                     TTVYQGIGFAKKDAELRDAYAAALKALMQSGEYKAIFAKYGLEGTLLDGIYINGEPAQ
                     "
     sig_peptide     complement(1498668..1498730)
                     /locus_tag="Smed_4984"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.990 at
                     residue 21"
     misc_feature    complement(1497954..1498634)
                     /locus_tag="Smed_4984"
                     /note="Bacterial periplasmic transport systems use
                     membrane-bound complexes and substrate-bound,
                     membrane-associated, periplasmic binding proteins (PBPs)
                     to transport a wide variety of  substrates, such as, amino
                     acids, peptides, sugars, vitamins and inorganic...;
                     Region: PBPb; cd00134"
                     /db_xref="CDD:238078"
     misc_feature    complement(1497948..1498616)
                     /locus_tag="Smed_4984"
                     /note="Bacterial extracellular solute-binding proteins,
                     family 3; Region: SBP_bac_3; pfam00497"
                     /db_xref="CDD:215950"
     misc_feature    complement(order(1498143..1498145,1498284..1498286,
                     1498416..1498418,1498491..1498493,1498608..1498610))
                     /locus_tag="Smed_4984"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:238078"
     misc_feature    complement(order(1498164..1498166,1498182..1498184,
                     1498194..1498196))
                     /locus_tag="Smed_4984"
                     /note="membrane-bound complex binding site; other site"
                     /db_xref="CDD:238078"
     misc_feature    complement(1498053..1498070)
                     /locus_tag="Smed_4984"
                     /note="hinge residues; other site"
                     /db_xref="CDD:238078"
     gene            complement(1498793..1499563)
                     /locus_tag="Smed_4985"
                     /db_xref="GeneID:5318798"
     CDS             complement(1498793..1499563)
                     /locus_tag="Smed_4985"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21096 putative amino acid transporter ABC
                     transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313699.1"
                     /db_xref="GI:150377103"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318798"
                     /translation="MNQDILVKAIDVTKNYGTFRALDKVSLEVARGEVSCIIGPSGSG
                     KSTLLRCINLLERMDGGGIWVNDELIGYRREGNNLHEISDAEISRQRRRIGMVFQRFN
                     LFPHKTALENIIEGPVHVLGEPVKEARSRASALLERVGLADKADHYPSELSGGQQQRV
                     AIARAMGMRPDLILFDEPTSALDPELVSEVLDVMRDLAASGMTMIVVTHELGFARNVA
                     NTVTFMETGKVVETGLASEVLSTPKSARTEEFIKAVHS"
     misc_feature    complement(1498799..1499548)
                     /locus_tag="Smed_4985"
                     /note="ABC-type polar amino acid transport system, ATPase
                     component [Amino acid transport and metabolism]; Region:
                     GlnQ; COG1126"
                     /db_xref="CDD:224051"
     misc_feature    complement(1498877..1499545)
                     /locus_tag="Smed_4985"
                     /note="ATP-binding cassette domain of the histidine and
                     glutamine transporters; Region: ABC_HisP_GlnQ; cd03262"
                     /db_xref="CDD:213229"
     misc_feature    complement(1499426..1499449)
                     /locus_tag="Smed_4985"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(order(1498937..1498939,1499033..1499038,
                     1499267..1499269,1499423..1499431,1499435..1499440))
                     /locus_tag="Smed_4985"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(1499267..1499278)
                     /locus_tag="Smed_4985"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(1499081..1499110)
                     /locus_tag="Smed_4985"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(1499033..1499050)
                     /locus_tag="Smed_4985"
                     /note="Walker B; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(1499015..1499026)
                     /locus_tag="Smed_4985"
                     /note="D-loop; other site"
                     /db_xref="CDD:213229"
     misc_feature    complement(1498931..1498951)
                     /locus_tag="Smed_4985"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213229"
     gene            complement(1499572..1500444)
                     /locus_tag="Smed_4986"
                     /db_xref="GeneID:5318799"
     CDS             complement(1499572..1500444)
                     /locus_tag="Smed_4986"
                     /note="TIGRFAM: polar amino acid ABC transporter, inner
                     membrane subunit;
                     PFAM: binding-protein-dependent transport systems inner
                     membrane component;
                     KEGG: sme:SMb21095 putative amino acid uptake ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="polar amino acid ABC transporter inner membrane
                     subunit"
                     /protein_id="YP_001313700.1"
                     /db_xref="GI:150377104"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR010065"
                     /db_xref="GeneID:5318799"
                     /translation="MNVANLTSSPTDAKYEIAHLKLVPKRHIGRMVAAGIVLLLLAGL
                     VRAFSVGQIEWSYVRDFLFAPAILAGLYNTLLMTIAAMGVGIVLGVVIAIMRISGNPV
                     LSSIAIGYVWVFRGAPALLQLMLWFNLALIFPTLGIPGLFEFRTVDVMTPFVAAVLGL
                     GLSQGAYTSEVVRSGLLSVDSGQYEAARTIGMTQMMMLRRIVLPQAMRVMVPPVGNEV
                     IGMVKLTSLASVIQYSEILHNAQIIYFANTRVLELLLVASFWYLLVVSVLSVGQHYIE
                     RYFGRGSKSIRSSM"
     misc_feature    complement(1499635..1500147)
                     /locus_tag="Smed_4986"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1499635..1499640,1499647..1499652,
                     1499659..1499664,1499668..1499673,1499680..1499685,
                     1499713..1499718,1499755..1499760,1499767..1499778,
                     1499797..1499799,1499806..1499811,1499851..1499853,
                     1499902..1499904,1499911..1499916,1499926..1499928,
                     1499932..1499937,1499944..1499946,1499950..1499952,
                     1499956..1499961,1500055..1500057,1500070..1500075,
                     1500082..1500111,1500115..1500126))
                     /locus_tag="Smed_4986"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1499761..1499778,1500055..1500060,
                     1500070..1500108))
                     /locus_tag="Smed_4986"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1499683..1499685,1499713..1499715,
                     1499722..1499724,1499758..1499760,1499974..1499976,
                     1500055..1500057))
                     /locus_tag="Smed_4986"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(1499830..1499832,1499842..1499847,
                     1499863..1499901))
                     /locus_tag="Smed_4986"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            complement(1500441..1501907)
                     /locus_tag="Smed_4987"
                     /db_xref="GeneID:5318800"
     CDS             complement(1500441..1501907)
                     /locus_tag="Smed_4987"
                     /EC_number="4.3.2.1"
                     /note="catalyzes the formation of arginine from
                     (N-L-arginino)succinate"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="YP_001313701.1"
                     /db_xref="GI:150377105"
                     /db_xref="InterPro:IPR000362"
                     /db_xref="InterPro:IPR003031"
                     /db_xref="InterPro:IPR009049"
                     /db_xref="GeneID:5318800"
                     /translation="MAEPTQLWGGRFKSGPSEALANLSRAPSSYFRLYREDIAGSRAH
                     ASELKRAGVLDEGEFSAIRAALEAIETDVGAGHEKPIAADEDLHTFLERLLMARLGAL
                     GGKLRAGRSRNDQTANNTRLYLRRMARELSRGIIAVEEALTEQASRHTETVMPGFTHL
                     QPAQPVVLGHHLMAHAQSLLRDLQRFADWDRRFDRSPLGAAALAGSGIARRPDLSAVD
                     LGYSAACENSIDAVAARDHVAEFLFICSLVAVDLSRLAEEICLWSSKQFSWVRLDDAY
                     STGSSIMPQKKNPDVAELTRGMSGTLIGNIAGFLATMKAMPLAYNRDLAEDKRSLFET
                     IDILDLVLPAFAGMVGTLEFDVEKLREEAPKGFTLATEVADWLVGRDVPFAEAHEITG
                     AVVRYCEERGHDLAGLTPDDLAKIDPRLHAGMLAALTLDKALASRTGYGATAPERVRE
                     QIARFETALAECRAFAAAPSGGAAFAGPKSDVEEERRR"
     misc_feature    complement(1500528..1501892)
                     /locus_tag="Smed_4987"
                     /note="argininosuccinate lyase; Provisional; Region:
                     PRK00855"
                     /db_xref="CDD:179143"
     misc_feature    complement(1500531..1501829)
                     /locus_tag="Smed_4987"
                     /note="Argininosuccinate lyase (argininosuccinase, ASAL);
                     Region: Argininosuccinate_lyase; cd01359"
                     /db_xref="CDD:176463"
     misc_feature    complement(order(1500924..1500929,1500933..1500935,
                     1500942..1500944,1500948..1500950,1501029..1501031,
                     1501038..1501040,1501044..1501046,1501068..1501070,
                     1501074..1501076,1501203..1501205,1501431..1501436,
                     1501560..1501562,1501569..1501577,1501644..1501646,
                     1501650..1501652,1501818..1501820))
                     /locus_tag="Smed_4987"
                     /note="active sites [active]"
                     /db_xref="CDD:176463"
     misc_feature    complement(order(1500555..1500557,1500579..1500593,
                     1500597..1500599,1500735..1500737,1500744..1500746,
                     1500753..1500758,1500783..1500785,1500798..1500800,
                     1500879..1500881,1500888..1500890,1500921..1500923,
                     1500930..1500932,1500939..1500950,1500972..1500980,
                     1500984..1500986,1500993..1501001,1501005..1501022,
                     1501026..1501031,1501038..1501040,1501044..1501052,
                     1501056..1501067,1501083..1501085,1501107..1501109,
                     1501116..1501121,1501134..1501139,1501146..1501151,
                     1501155..1501160,1501167..1501169,1501179..1501181,
                     1501188..1501190,1501200..1501202,1501206..1501211,
                     1501218..1501232,1501272..1501274,1501281..1501283,
                     1501287..1501301,1501332..1501334,1501344..1501346,
                     1501353..1501358,1501365..1501367,1501383..1501388,
                     1501398..1501400,1501416..1501439,1501584..1501589,
                     1501596..1501598,1501605..1501607))
                     /locus_tag="Smed_4987"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176463"
     gene            1502162..1503064
                     /locus_tag="Smed_4988"
                     /db_xref="GeneID:5318801"
     CDS             1502162..1503064
                     /locus_tag="Smed_4988"
                     /note="PFAM: regulatory protein LysR; LysR
                     substrate-binding;
                     KEGG: sme:SMb21093 putative transcriptional regulator,
                     LysR family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="YP_001313702.1"
                     /db_xref="GI:150377106"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="GeneID:5318801"
                     /translation="MASGRRRLPSTTALQVLLAVAERGSTSAAAESTSLSQSAVSKQL
                     LALEALIGSSAFARTSRGMIPTEVGSIYIEQARIALKAIEDAALRVARLKPGPRVLRL
                     QVPPIFGDRWLLPRFLRFTEQHPEIEVQFTTFVSPTQSETPDAIFRFLTEPLPGEETS
                     YLFGREVLVVSAPSYWEKNGTPETIEELADGVMLEHPQTPLHWHYFADSHGKRELPVR
                     HTTRFGYYTMVIRAALAGQGMALIPRGLILDDLAAGKLVNPNGFGYRSEYGYWFAKPR
                     DIAPSASMRIFETWLMAEAEGMGD"
     sig_peptide     1502162..1502248
                     /locus_tag="Smed_4988"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.725) with cleavage site probability 0.362 at
                     residue 29"
     misc_feature    1502177..1503049
                     /locus_tag="Smed_4988"
                     /note="DNA-binding transcriptional activator GcvA;
                     Provisional; Region: PRK11139"
                     /db_xref="CDD:182990"
     misc_feature    1502198..1502368
                     /locus_tag="Smed_4988"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:215735"
     misc_feature    1502456..1503034
                     /locus_tag="Smed_4988"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulators (LTTRs), a member of the type 2
                     periplasmic binding fold protein superfamily; Region:
                     PBP2_LTTR_substrate; cl11398"
                     /db_xref="CDD:245600"
     misc_feature    order(1502501..1502506,1502510..1502515,1502522..1502524,
                     1502534..1502536,1502540..1502560,1502819..1502836,
                     1502852..1502857,1502861..1502866)
                     /locus_tag="Smed_4988"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176102"
     gene            complement(1503226..1503696)
                     /locus_tag="Smed_4989"
                     /db_xref="GeneID:5318710"
     CDS             complement(1503226..1503696)
                     /locus_tag="Smed_4989"
                     /note="PFAM: GCN5-related N-acetyltransferase;
                     KEGG: sme:SMb21092 putative acetyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase GCN5"
                     /protein_id="YP_001313703.1"
                     /db_xref="GI:150377107"
                     /db_xref="InterPro:IPR000182"
                     /db_xref="GeneID:5318710"
                     /translation="MLPIRLLQPDDPALPALAILMEEMQAHYRVACPPRSEIIAGLKA
                     MPRGAEILVAEEQHRILGFAGFSGIYPGPGLKPGLFLKELYVAGSQRGRGLGRALMQK
                     LASVATQRGLSRIDWTADAENARLLAFYEELGGACKTDKLFFRLDGEALVQLAN"
     misc_feature    complement(1503352..1503546)
                     /locus_tag="Smed_4989"
                     /note="N-Acyltransferase superfamily: Various enzymes that
                     characteristically catalyze the transfer of an acyl group
                     to a substrate; Region: NAT_SF; cd04301"
                     /db_xref="CDD:173926"
     misc_feature    complement(order(1503406..1503411,1503439..1503447))
                     /locus_tag="Smed_4989"
                     /note="Coenzyme A binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173926"
     gene            complement(1503718..1504719)
                     /locus_tag="Smed_4990"
                     /db_xref="GeneID:5318711"
     CDS             complement(1503718..1504719)
                     /locus_tag="Smed_4990"
                     /note="PFAM: glycoside hydrolase family 25;
                     KEGG: sme:SMb21091 putative cell-wall lytic enzyme,
                     similar to muramidase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="YP_001313704.1"
                     /db_xref="GI:150377108"
                     /db_xref="InterPro:IPR002053"
                     /db_xref="GeneID:5318711"
                     /translation="MRHFSVVSAIVIFGLVLSGCGFGGDRPSRETTSSVRPASPVPSA
                     EVSAVAAKSAPEALAWAGPVPEPQAFTSAQRTVGMPVPAERPLAMLAPENPAGPRGGR
                     TRVYSHSFRDAHPINFGKRSPRKMAVHGVDVSRWQGDINWAKLRSQGANFAYIKATDG
                     GDHLDPMFKKNWRRANEAGLKRGAYHFFYWCRTAGEQADWFIRNVPRDPTALPPVIDV
                     EWNGESSCKRRPSRERVLEKMQVFMDKLERHYGQRPIIYTAPDFYRDNLQGAFPNHPF
                     WLRSVAAHPSKVYPGRKWVFWQYSGSGLSHGVEGRIDLNVFNGSEEDWHNWVAARSS"
     sig_peptide     complement(1504648..1504719)
                     /locus_tag="Smed_4990"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.957) with cleavage site probability 0.940 at
                     residue 24"
     misc_feature    complement(1503721..1504500)
                     /locus_tag="Smed_4990"
                     /note="Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell
                     envelope biogenesis, outer membrane]; Region: Acm;
                     COG3757"
                     /db_xref="CDD:226280"
     misc_feature    complement(1503763..1504341)
                     /locus_tag="Smed_4990"
                     /note="Uncharacterized bacterial muramidase containing a
                     glycosyl hydrolase family 25 (GH25) catalytic domain.
                     Endo-N-acetylmuramidases are lysozymes (also referred to
                     as peptidoglycan hydrolases) that degrade bacterial cell
                     walls by catalyzing the hydrolysis...; Region:
                     GH25_muramidase_1; cd06413"
                     /db_xref="CDD:119375"
     misc_feature    complement(order(1503781..1503783,1503826..1503828,
                     1503889..1503891,1503949..1503951,1504063..1504065,
                     1504069..1504071,1504159..1504161,1504165..1504167,
                     1504252..1504254,1504324..1504326))
                     /locus_tag="Smed_4990"
                     /note="active site"
                     /db_xref="CDD:119375"
     gene            complement(1504933..1506063)
                     /locus_tag="Smed_4991"
                     /db_xref="GeneID:5318712"
     CDS             complement(1504933..1506063)
                     /locus_tag="Smed_4991"
                     /note="KEGG: sme:SMb21090 conserved hypothetical
                     membrane-anchored protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313705.1"
                     /db_xref="GI:150377109"
                     /db_xref="GeneID:5318712"
                     /translation="MNLVLKGMTWNHPRGYDPMVACSRAWQETSGVEIQWEKRSLQDF
                     ETFPVEVLARDYDLIVIDHPHVGQITSENCLLPLDVPGREADRQALSAASVGPSYRSY
                     EWNARQWAFPIDAATQVQAWRPDRTERLRTWREVLDLARSGGVVLPLRPPHSLMSFFT
                     LCGNLGRPCRSNGQGELVDAETGAAAIELLKEIAALVDPDCFDMDPIAAFEAMAEKGS
                     AFACAPLIYGYVSYSMAGFRPALIRFGDIPEIGAAGPVGSALGGTGIAVSAFSKAPEQ
                     AIDFAYWVASGDVQRGIYAACGGQPGHGAAWQDETVNAATHDFYRATRATLEAAWLRP
                     RHDGYMAFQQAGSDRLNEGLKRGERPSLVAEELNRLFCESFR"
     misc_feature    complement(1505014..1506042)
                     /locus_tag="Smed_4991"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     UgpB; COG1653"
                     /db_xref="CDD:224567"
     gene            complement(1506060..1507220)
                     /locus_tag="Smed_4992"
                     /db_xref="GeneID:5318713"
     CDS             complement(1506060..1507220)
                     /locus_tag="Smed_4992"
                     /note="PFAM: L-carnitine dehydratase/bile acid-inducible
                     protein F;
                     KEGG: mlo:mll7158 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine dehydratase/bile acid-inducible
                     protein F"
                     /protein_id="YP_001313706.1"
                     /db_xref="GI:150377110"
                     /db_xref="InterPro:IPR003673"
                     /db_xref="GeneID:5318713"
                     /translation="MTTESELPLAGLVVVDMSQFLSGPYCSLRLMDLGARVIKIERPD
                     GGDLSRRLYLSDTEIGGDSTIFHAINRAKESLAIDLKNEDDLAALKRLLAKADVMIQN
                     FRPGVIERLGLDYEAVRAINPRMVYASISGYGEEGPWLKRPGQDLLAQARSGVMWLNG
                     DEGQGPVPFGLAIGDMLAGAAAAQGILAALVRRGISGKGSLVETSLLEALVDFQFEVL
                     TTHLNDGRRLPKRSAFRSAHAYLSAPYGVYAASDGFLAIAMTPIPKLADLLQIDALAP
                     YRDDPSAWFTERDPIKALIAARIAERTLDEWLAVLEPADIWCARVLDWNELLDSEGFQ
                     VLDMLQTVMREDDVSITTTRSPLRINGRRPSVERAAPRIGEHGASIREEFGL"
     misc_feature    complement(1506063..1507208)
                     /locus_tag="Smed_4992"
                     /note="Predicted acyl-CoA transferases/carnitine
                     dehydratase [Energy production and conversion]; Region:
                     CaiB; COG1804"
                     /db_xref="CDD:224717"
     misc_feature    complement(1506450..1506995)
                     /locus_tag="Smed_4992"
                     /note="CoA-transferase family III; Region: CoA_transf_3;
                     pfam02515"
                     /db_xref="CDD:217078"
     gene            1507504..1508805
                     /locus_tag="Smed_4993"
                     /db_xref="GeneID:5318714"
     CDS             1507504..1508805
                     /locus_tag="Smed_4993"
                     /note="PFAM: Capsule polysaccharide biosynthesis protein;
                     KEGG: sme:SMb20834 probable surface saccharide synthesis
                     protein, possibly involved in chain-length determination"
                     /codon_start=1
                     /transl_table=11
                     /product="capsule polysaccharide biosynthesis protein"
                     /protein_id="YP_001313707.1"
                     /db_xref="GI:150377111"
                     /db_xref="InterPro:IPR007833"
                     /db_xref="GeneID:5318714"
                     /translation="MKPHAGEGSRATDFGSGAAPQGRRTTFAVQITEWKREPFERYFP
                     DRHFHFLPMNLGEHEFERVWKPRILAESSAEILAWGPELPGPLDALAKARNIPVTFIE
                     DGFLRSARPSASRTPPLSLALDSKAIYFDCRHPSQLEELLGTYDFEADAELMTRARAG
                     IALLTESGISKYNGGRQRTAEEVYGEKTRKRVLVVGQVEDDASVRYGCLSRMTNNDLV
                     RLAASEQPDAQILYKPHPDVLSRVRPARSDPAEVAHLCTLVTESLPLAEALRTVDHVY
                     TITSLAGFEALIRGIEVSTAGCPFYSGWGLTDDRQPNPRRGRRLSIEALFAGAYLLYP
                     CYFDPETGERSSFEATVATLRSQLEEPQGLARPRPAWRAWGPYGLLGWRHLLPPFVTP
                     VIRKIGSDRDVEDFRADPIRFFRTLSDRKFRVIGRILYPFG"
     misc_feature    1507729..1508511
                     /locus_tag="Smed_4993"
                     /note="Capsule polysaccharide biosynthesis protein;
                     Region: Capsule_synth; pfam05159"
                     /db_xref="CDD:218473"
     gene            1508811..1509581
                     /locus_tag="Smed_4994"
                     /db_xref="GeneID:5318715"
     CDS             1508811..1509581
                     /locus_tag="Smed_4994"
                     /note="PFAM: ABC-2 type transporter;
                     KEGG: sme:SMb20833 putative cell surface polysaccharide
                     export ABC-2 transporter permease protein, close relative
                     of Y20822wzm2"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 type transporter"
                     /protein_id="YP_001313708.1"
                     /db_xref="GI:150377112"
                     /db_xref="InterPro:IPR000412"
                     /db_xref="InterPro:IPR013525"
                     /db_xref="InterPro:IPR013526"
                     /db_xref="GeneID:5318715"
                     /translation="MEYVATHLRVVAALLVREMSTRFGSKPGGYVWALLDPAAHILLM
                     TSIFQAIAHTPALGTSFALFFATGYIAFQFYQAMNGYLNAAVKANKALLSYPNVAPID
                     TIVARFVLQMGTTSLVAFIVLGTIVATMRVDTDLHWPSILEAIALACLFGLGVALINC
                     VLFLKYPLYEQVFGIVNRPLFLISGVFFLPDSIPAPYRELVLINPLVHIIMGFRKGFY
                     PEYRAIGLDMDYLYGIAFLTLFAGMLVFTLSRKTLRNE"
     misc_feature    1508811..1509578
                     /locus_tag="Smed_4994"
                     /note="ABC-type polysaccharide/polyol phosphate export
                     systems, permease component [Carbohydrate transport and
                     metabolism / Cell envelope biogenesis, outer membrane];
                     Region: TagG; COG1682"
                     /db_xref="CDD:224596"
     misc_feature    1508835..1509464
                     /locus_tag="Smed_4994"
                     /note="ABC-2 type transporter; Region: ABC2_membrane;
                     pfam01061"
                     /db_xref="CDD:216273"
     gene            1509578..1510237
                     /locus_tag="Smed_4995"
                     /db_xref="GeneID:5318716"
     CDS             1509578..1510237
                     /locus_tag="Smed_4995"
                     /note="PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20832 putative cell surface polysaccharide
                     export ABC-2 transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313709.1"
                     /db_xref="GI:150377113"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="GeneID:5318716"
                     /translation="MIRFEQATKYARTKGIKKPIIEDASLTLNRGKSVGLLGRNGAGK
                     STLLRLIAGAIKLDGGRIIRRGKISWPLGFAGSFQSSMTGEQNVRFVARIYGVNTEQL
                     IAYVEDFAELGPFFKAPVGTYSSGMKARLAFGLSMGVNFDYYLVDEITAVGDTNFKKK
                     CQAVFETRLQDSDVVMVSHSTGTIRDYCDCGVVLEKGKMTYYENVEDAIRAHDKNMKE
                     S"
     misc_feature    1509578..1510171
                     /locus_tag="Smed_4995"
                     /note="ABC-type cobalt transport system, ATPase component
                     [Inorganic ion transport and metabolism]; Region: CbiO;
                     COG1122"
                     /db_xref="CDD:224047"
     misc_feature    1509581..1510186
                     /locus_tag="Smed_4995"
                     /note="ATP-binding cassette component of polysaccharide
                     transport system; Region: ABC_KpsT_Wzt; cd03220"
                     /db_xref="CDD:213187"
     misc_feature    1509689..1509712
                     /locus_tag="Smed_4995"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213187"
     misc_feature    order(1509698..1509703,1509707..1509715,1509908..1509910,
                     1510016..1510021,1510112..1510114)
                     /locus_tag="Smed_4995"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213187"
     misc_feature    1509899..1509910
                     /locus_tag="Smed_4995"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213187"
     misc_feature    1509944..1509973
                     /locus_tag="Smed_4995"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213187"
     misc_feature    1510004..1510021
                     /locus_tag="Smed_4995"
                     /note="Walker B; other site"
                     /db_xref="CDD:213187"
     misc_feature    1510028..1510039
                     /locus_tag="Smed_4995"
                     /note="D-loop; other site"
                     /db_xref="CDD:213187"
     misc_feature    1510100..1510120
                     /locus_tag="Smed_4995"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213187"
     gene            1510238..1511569
                     /locus_tag="Smed_4996"
                     /db_xref="GeneID:5318717"
     CDS             1510238..1511569
                     /locus_tag="Smed_4996"
                     /note="KEGG: sme:SMb20831 putative polysaccharide
                     export-assoiated protein"
                     /codon_start=1
                     /transl_table=11
                     /product="capsule polysaccharide export protein-like
                     protein"
                     /protein_id="YP_001313710.1"
                     /db_xref="GI:150377114"
                     /db_xref="GeneID:5318717"
                     /translation="MAASKDAAVNKADSAQAAGKDVSATAAAKSKGIAVLEGLLGKES
                     APVIPLPGRQKAFPPKKTGWKAGWLKKLRWRHAIIGGTFLGLVAVPATLASLYMAFIA
                     ADQYHSTTSFAVRSIEGGVSSDILGMFTQASGGSTVSDSYILMDYILSERMAADADRR
                     FKLEDVYATRGLDYFYGIGSELPIEDKLDYWRDMVNVNFDHASGIMQVTVKAFEPRQA
                     REIAKFIVDQSDNLVNSLSLSARNDVLRAAQDEVLAGEARLSKARAALRDYRDKSQEI
                     SPEEGAKLAVQLIGSLEQQLTQLNADLATAKSQMGEDTPRIRVLKTRIESLEQQLDVE
                     RQRLGAGEKSAAGNDPNSPDVAGRIAEFEELETEREFAERAYTAALGSLEKARIDANN
                     RQRYLALFIEPTLSELAQYPARLLNSFLVMLGLLFAWGIGVMGYYNIRDRA"
     misc_feature    1510493..1511566
                     /locus_tag="Smed_4996"
                     /note="Capsule polysaccharide export protein [Cell
                     envelope biogenesis, outer membrane]; Region: KpsE;
                     COG3524"
                     /db_xref="CDD:226055"
     gene            complement(1511623..1512624)
                     /locus_tag="Smed_4997"
                     /db_xref="GeneID:5318718"
     CDS             complement(1511623..1512624)
                     /locus_tag="Smed_4997"
                     /EC_number="5.3.1.13"
                     /note="TIGRFAM: KpsF/GutQ family protein;
                     PFAM: CBS domain containing protein; sugar isomerase
                     (SIS);
                     KEGG: sme:SMc02268 putative capsule expression protein"
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family protein"
                     /protein_id="YP_001313711.1"
                     /db_xref="GI:150377115"
                     /db_xref="InterPro:IPR000644"
                     /db_xref="InterPro:IPR001199"
                     /db_xref="InterPro:IPR001347"
                     /db_xref="InterPro:IPR004800"
                     /db_xref="GeneID:5318718"
                     /translation="MQAKADGNAGVTVLESIGRTLATATNGIRALADHLSSDETFADA
                     LVNAVELMGDGDGRVVVSGVGKSGHIGRKIAATLASTGTSAYFVHPTEASHGDLGMIT
                     AQDALVLLSWSGETAELANMLTYAKRFKVPIISICSNRESTLARNSEVALVLPKVPEA
                     CPHGLAPTTSAMLQLAIGDALAIALLERRGFSAEDFKTFHPGGKLGAQLRLVHELAHG
                     AGQMPLLPVGRPMSEAVIEMSAKGFGVVGIVDESGKLVGVITDGDMRRHMTADLLAQP
                     VEAIMSHNPRVLSRDVLASAAMEFMEEHKITVLFLVGDAGAPVGILHIHDLLRAGVA"
     misc_feature    complement(1511656..1512420)
                     /locus_tag="Smed_4997"
                     /note="KpsF/GutQ family protein; Region: kpsF; TIGR00393"
                     /db_xref="CDD:129488"
     misc_feature    complement(1512109..1512420)
                     /locus_tag="Smed_4997"
                     /note="KpsF-like protein. KpsF is an arabinose-5-phosphate
                     isomerase which contains SIS (Sugar ISomerase) domains.
                     SIS domains are found in many phosphosugar isomerases and
                     phosphosugar binding proteins. KpsF catalyzes the
                     reversible reaction of ribulose...; Region: SIS_Kpsf;
                     cd05014"
                     /db_xref="CDD:240145"
     misc_feature    complement(1512292..1512294)
                     /locus_tag="Smed_4997"
                     /note="putative active site [active]"
                     /db_xref="CDD:240145"
     misc_feature    complement(1511635..1511964)
                     /locus_tag="Smed_4997"
                     /note="This cd contains two tandem repeats of the
                     cystathionine beta-synthase (CBS pair) domains associated
                     with KpsF/GutQ domains in the API [A5P (D-arabinose
                     5-phosphate) isomerase] protein.  These APIs catalyze the
                     conversion of the pentose pathway...; Region:
                     CBS_pair_KpsF_GutQ_assoc; cd04604"
                     /db_xref="CDD:239977"
     gene            1513014..1514006
                     /locus_tag="Smed_4998"
                     /db_xref="GeneID:5318719"
     CDS             1513014..1514006
                     /locus_tag="Smed_4998"
                     /note="TIGRFAM: UDP-glucose 4-epimerase;
                     PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase; polysaccharide
                     biosynthesis protein CapD; dTDP-4-dehydrorhamnose
                     reductase; Male sterility domain;
                     KEGG: sme:SMc02252 probable UDP-glucose 4-epimerase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="YP_001313712.1"
                     /db_xref="GI:150377116"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005886"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="GeneID:5318719"
                     /translation="MAILVTGGAGYIGSHMVWCLLDAHEDVVVLDRLSTGFRWAVAPE
                     AKFYEGDIGDSELLNRIFASHDIEAIIHFAGSVVVPESVADPLTYYDNNTVKSRALIA
                     SAVKAKIKYFVFSSTAAVYGTPDGNGPVNEAAPLRPESPYGSSKLMTEIMLKDAAFAH
                     DITYTVLRYFNVAGADVHGRTGQSTAGATHLIKVACEAALGKRNGIDVYGADYPTPDG
                     TCIRDFIHVTDLVNAHLRALERMRAGGSSIVANCGYGRGFSVLDVLHQVKQASGVDFP
                     VRIVERRPGDAVSVVADPMRITRELAWEPCHDDLNFIVRTSLDWESRLSRRNTY"
     misc_feature    1513014..1513982
                     /locus_tag="Smed_4998"
                     /note="UDP-glucose 4-epimerase [Cell envelope biogenesis,
                     outer membrane]; Region: GalE; COG1087"
                     /db_xref="CDD:224012"
     misc_feature    1513017..1513979
                     /locus_tag="Smed_4998"
                     /note="UDP-glucose 4 epimerase, subgroup 1, extended (e)
                     SDRs; Region: UDP_G4E_1_SDR_e; cd05247"
                     /db_xref="CDD:187558"
     misc_feature    order(1513032..1513034,1513038..1513049,1513104..1513121,
                     1513161..1513169,1513230..1513238,1513242..1513244,
                     1513287..1513289,1513356..1513364,1513437..1513439,
                     1513449..1513451,1513518..1513523,1513527..1513529)
                     /locus_tag="Smed_4998"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:187558"
     misc_feature    order(1513260..1513262,1513266..1513274,1513281..1513286,
                     1513293..1513298,1513305..1513310,1513314..1513319,
                     1513326..1513328,1513434..1513436,1513443..1513445,
                     1513455..1513457,1513464..1513469,1513473..1513481)
                     /locus_tag="Smed_4998"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187558"
     misc_feature    order(1513290..1513292,1513362..1513364,1513437..1513439,
                     1513449..1513451)
                     /locus_tag="Smed_4998"
                     /note="active site"
                     /db_xref="CDD:187558"
     misc_feature    order(1513362..1513370,1513437..1513439,1513518..1513526,
                     1513578..1513586,1513629..1513640,1513671..1513673,
                     1513677..1513679,1513683..1513685,1513791..1513793,
                     1513860..1513862,1513869..1513871)
                     /locus_tag="Smed_4998"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:187558"
     gene            1514089..1515114
                     /locus_tag="Smed_4999"
                     /db_xref="GeneID:5318720"
     CDS             1514089..1515114
                     /locus_tag="Smed_4999"
                     /note="PFAM: Capsule polysaccharide biosynthesis protein;
                     KEGG: sme:SMb20823 putative cell surface saccharide
                     synthesis protein, possibly involved in chain-length
                     determination, truncated N-terminus"
                     /codon_start=1
                     /transl_table=11
                     /product="capsule polysaccharide biosynthesis protein"
                     /protein_id="YP_001313713.1"
                     /db_xref="GI:150377117"
                     /db_xref="InterPro:IPR007833"
                     /db_xref="GeneID:5318720"
                     /translation="MTTAFVFGLSPWKDFIRSWLPEERIYCQKRTISWLEFHAVWAPL
                     ILVSKDPKIYVWGYKHPPFIERFSRLSRVNLIRIEDGFIRSVALGASKAPPLSLCFDS
                     PVLYYDPSSQSTLERLIETYHFSADPALLLRARTGMNRLVSSRLSKYNTSQDVDVHRI
                     YGPKDCKRILVLGQVEDDMSIIKGCSRLMTNNDLVRLAVQENPGAQVIYKPHPEVLHG
                     TRLARSSPEEVRPIAQVLDDDIALADAFETIDHVYTITSLSGFEALIRGIKVTCLGMP
                     FYAGWGLTDDRQSCLRRSAKRSVEEVFAAAYLLYPKYFHPHEKKMISFEEALELLHSM
                     KHASATP"
     misc_feature    1514245..1515027
                     /locus_tag="Smed_4999"
                     /note="Capsule polysaccharide biosynthesis protein;
                     Region: Capsule_synth; pfam05159"
                     /db_xref="CDD:218473"
     gene            1515366..1517090
                     /locus_tag="Smed_5000"
                     /db_xref="GeneID:5318649"
     CDS             1515366..1517090
                     /locus_tag="Smed_5000"
                     /note="PFAM: Hemolysin-type calcium-binding region;
                     KEGG: sme:SMb20829 putative secreted calcium-binding
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Hemolysin-type calcium-binding protein"
                     /protein_id="YP_001313714.1"
                     /db_xref="GI:150377118"
                     /db_xref="InterPro:IPR001343"
                     /db_xref="GeneID:5318649"
                     /translation="MAAYSCSKTHAFFIHFHHFFWPETSRLPEEIMATITYHFPAGLY
                     PNQYNPPLSGVSVNPSFGELVDMSTGSRSTTTSTSVLYRLDNGLKMKLVGTGFSFDAS
                     GDAVGGTITSIEVLLNNGTGLIQTISGLNISLELFQDASAAFDSSGLESWLASGNDTI
                     NGSLGNDEIWGRLGNDVLNGNAGNDLVTGGGGADTYDGGAGFDILNFQDAYDSPTAIR
                     GINLNATAGTVVDQFGFSETFQNFEEFRGTQFSDSMMGSSVDETFFGFGGRDNINGGA
                     GIDTVRYDRDFQRGATKGVSIDLSTGIATDGFGSRDTLTSIENIRATEFKDTIVGSSA
                     ANFLRTFAGNDSINGGGGSDNMRGGIGNDTYFVDNTGDIVDEAADSGAGTDTVQSTVS
                     FNLGNTAVAKGGVENLVLLGTGNINGTGNALNNTLSGNTGNNTFSGFAGNDTIDGGLG
                     NDLINGGLGNDSLTGGAGLDTFNFSNALDATNNVDTINGFVVADDTIRLENAVFTGIV
                     GTGTLTAAQFVTNTTGLAADADDRIIYDSDTGRLLYDSDGDGAGGSVHFATVGTNLGM
                     TASDFFVV"
     gene            complement(1517160..1517837)
                     /locus_tag="Smed_5001"
                     /db_xref="GeneID:5318650"
     CDS             complement(1517160..1517837)
                     /locus_tag="Smed_5001"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313715.1"
                     /db_xref="GI:150377119"
                     /db_xref="GeneID:5318650"
                     /translation="MSVAMHNALLESETRQAKLLFELDWRVDDPSTYILDDVDTPCER
                     STKMRAKYYQELHDENDAYQVNNWLVAEKASILKAKPKTLVEVGCGNGAFSLSTAEDL
                     EKVFAVDWALSPKFGGRPENVEFVQADVTQDRLPKADVVCSADVLEHFTPWNVTRVLE
                     NCASAAALQYHVIACYDDGHSHLTVMRPAAWLASFWRYFPDARLTRIDCRREKHTQLV
                     CVITNIT"
     misc_feature    complement(1517349..1517591)
                     /locus_tag="Smed_5001"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases;
                     cd02440"
                     /db_xref="CDD:100107"
     misc_feature    complement(order(1517406..1517408,1517448..1517456,
                     1517508..1517513,1517559..1517579))
                     /locus_tag="Smed_5001"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            1518056..1520416
                     /locus_tag="Smed_5002"
                     /db_xref="GeneID:5318651"
     CDS             1518056..1520416
                     /locus_tag="Smed_5002"
                     /note="PFAM: Tetratricopeptide TPR_2 repeat protein;
                     KEGG: cjj:CJJ81176_1436 putative glycosyl transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313716.1"
                     /db_xref="GI:150377120"
                     /db_xref="InterPro:IPR013026"
                     /db_xref="InterPro:IPR013105"
                     /db_xref="GeneID:5318651"
                     /translation="MRYEQPALVRNSAAESPVLTVLITIRVAAHYDMIERLRFRSLDT
                     RMPDSVTFLVIDEGSSFEDAERLKAACAEIGFDYVRHNTEKDLFCLAGARNIGASLSR
                     SQFIMFEDVDLFPYPGFYQDIIDEIHVQGLDTHSNRFLTVPCLYLSEQATEAALAGTL
                     SKNEILHDHLTGGPLVDFALPASSALVINRMFYLSIGGSNDQFKGWGLEDLELAYRLT
                     RGTNKFMSPKDHRWLIEGGYAHNPTYRGWRAQFRLHGELLARKSIYIFHAHHPRDTAW
                     RNPELHRANKAIFQSSNESFDAKGHTLPSLPDAKRGRSLIFGRGTFAYNPALLPLWGD
                     LEVKGYQDFQERDIIEHVRANGINRVIFTNPYANDMRLSVYNRVRSAGIPFYVVERGA
                     LTDSMFIDDTGFCCESTRYRREHWPAELDAGRLRRVQDYISAETSSGSALEKQGERIG
                     ARAALQKLGIPPQKKVLFVPFQSRSDTTVNHFAGPIGSFDNFVDLVRDVTKRLPPDWV
                     VVFKKHPLSSVQETVPGAIDVGNMHIKDLMELTDYVLLMNSGVGVLSILFDRPCIYTA
                     QAFYADDALNRGASKAGDVLRLLKEGFTVDQDSRLRFLSYLLEDFYSFGKFTVTEKSY
                     TDNATLSITERIDYYRVNLLGARVLDTDDRERILNPNAPIYDLFREWIRSNKHTERQA
                     SPSGAPQSADEASRKGRSAFHAKRYQEAALMFDAACSIQPNRATHYRAAAEALFAMGN
                     RNIALSRLEKARLLAPDNKSIKRRIREMKRPPFLQFLSKPFPIAKD"
     misc_feature    1518113..1518943
                     /locus_tag="Smed_5002"
                     /note="Glycosyltransferase like family 2; Region:
                     Glyco_tranf_2_2; pfam10111"
                     /db_xref="CDD:220577"
     misc_feature    1518185..1518712
                     /locus_tag="Smed_5002"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cl11394"
                     /db_xref="CDD:245596"
     misc_feature    order(1518218..1518220,1518383..1518385,1518389..1518391)
                     /locus_tag="Smed_5002"
                     /note="active site"
                     /db_xref="CDD:132997"
     misc_feature    1519190..1519768
                     /locus_tag="Smed_5002"
                     /note="Capsule polysaccharide biosynthesis protein;
                     Region: Capsule_synth; pfam05159"
                     /db_xref="CDD:218473"
     misc_feature    1520120..1520323
                     /locus_tag="Smed_5002"
                     /note="TPR repeat; Region: TPR_11; pfam13414"
                     /db_xref="CDD:222112"
     misc_feature    1520144..>1520350
                     /locus_tag="Smed_5002"
                     /note="Tetratricopeptide repeat domain; typically contains
                     34 amino acids
                     [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-
                     X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in
                     a variety of organisms including bacteria, cyanobacteria,
                     yeast, fungi; Region: TPR; cd00189"
                     /db_xref="CDD:238112"
     misc_feature    order(1520147..1520149,1520183..1520185,1520195..1520197,
                     1520204..1520206,1520249..1520251,1520285..1520287,
                     1520297..1520299,1520306..1520308)
                     /locus_tag="Smed_5002"
                     /note="TPR motif; other site"
                     /db_xref="CDD:238112"
     misc_feature    order(1520150..1520155,1520240..1520245,1520249..1520254,
                     1520261..1520266,1520342..1520347)
                     /locus_tag="Smed_5002"
                     /note="binding surface"
                     /db_xref="CDD:238112"
     gene            complement(1520763..1521545)
                     /locus_tag="Smed_5003"
                     /db_xref="GeneID:5318652"
     CDS             complement(1520763..1521545)
                     /locus_tag="Smed_5003"
                     /note="PFAM: ABC-2 type transporter;
                     KEGG: sme:SMb20822 putative cell surface polysaccharide
                     export ABC-2 transporter permease protein, close relative
                     to wzm1Y20833"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 type transporter"
                     /protein_id="YP_001313717.1"
                     /db_xref="GI:150377121"
                     /db_xref="InterPro:IPR000412"
                     /db_xref="InterPro:IPR013525"
                     /db_xref="InterPro:IPR013526"
                     /db_xref="GeneID:5318652"
                     /translation="MKLIQQHLRVTAALIVREMSTRFGSKPGGYLWAIFDPVAHVAMM
                     TVIFQAIARTPALGLSFPLFFASGYLPFAFYQRMSSFMAGTVKANKALFSYPIVSPFD
                     AIVSRFILQLMTDTLVTILILVMILELSGVAQPMDIAGMIEAAGAAALLGLGMGTINI
                     VMFARFPLYEQIFGIINRPLFMVSGVFFLPDSLPHPFRDFILYNPLVHIIMWFRASIY
                     PEYRAYGLDKGYVIEFALVCAVAGLALLTTSTREIREDRLGA"
     misc_feature    complement(1520844..1521545)
                     /locus_tag="Smed_5003"
                     /note="ABC-type polysaccharide/polyol phosphate export
                     systems, permease component [Carbohydrate transport and
                     metabolism / Cell envelope biogenesis, outer membrane];
                     Region: TagG; COG1682"
                     /db_xref="CDD:224596"
     misc_feature    complement(1520844..1521506)
                     /locus_tag="Smed_5003"
                     /note="ABC-2 type transporter; Region: ABC2_membrane;
                     cl17235"
                     /db_xref="CDD:247789"
     gene            complement(1521863..1522663)
                     /locus_tag="Smed_5004"
                     /db_xref="GeneID:5318653"
     CDS             complement(1521863..1522663)
                     /locus_tag="Smed_5004"
                     /note="PFAM: Ketopantoate hydroxymethyltransferase;
                     KEGG: sme:SMb20821 putative ATPGTP-binding
                     hydroxymethyltransferase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate hydroxymethyltransferase"
                     /protein_id="YP_001313718.1"
                     /db_xref="GI:150377122"
                     /db_xref="InterPro:IPR003700"
                     /db_xref="GeneID:5318653"
                     /translation="MRHRRPTVADLLSMKGRRQLTMLRVVTLEEADAAEKAGIDLVSV
                     PPALLGPAFREAAPSVFAFPGLEYGDYVTTEDYMRAAFQALKAGGDAVYCAASLSTVR
                     RMREEGVPVCGHVGLIPSKATWTGGFRAVGTTAASALEVWRQTKALEEAGAFAAEIEV
                     VPDGIAAAISARSSMLMLSMGAGTGCDAQYLFAEDVLGSNRGHYPRHARTYRNFAAEY
                     DRLQQERIAAFREFASDVRTGAYPEKGHLVGVEQKELSAFLAELEGGR"
     misc_feature    complement(1521905..1522663)
                     /locus_tag="Smed_5004"
                     /note="Ketopantoate hydroxymethyltransferase [Coenzyme
                     metabolism]; Region: PanB; COG0413"
                     /db_xref="CDD:223490"
     misc_feature    complement(order(1521974..1521982,1521986..1521997,
                     1522019..1522021,1522202..1522204,1522334..1522351,
                     1522355..1522360,1522367..1522369,1522394..1522396,
                     1522406..1522408,1522415..1522420,1522427..1522432,
                     1522451..1522453,1522457..1522462,1522496..1522501,
                     1522508..1522510,1522511..1522513,1522520..1522528,
                     1522532..1522537,1522544..1522552,1522556..1522558,
                     1522565..1522570,1522574..1522588,1522592..1522603))
                     /locus_tag="Smed_5004"
                     /note="oligomerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:119341"
     misc_feature    complement(order(1522088..1522090,1522118..1522120,
                     1522124..1522126,1522187..1522189,1522322..1522324,
                     1522463..1522465,1522469..1522471,1522535..1522537))
                     /locus_tag="Smed_5004"
                     /note="active site"
                     /db_xref="CDD:119341"
     misc_feature    complement(order(1522385..1522387,1522463..1522465,
                     1522469..1522471))
                     /locus_tag="Smed_5004"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:119341"
     gene            complement(1522703..1523929)
                     /locus_tag="Smed_5005"
                     /db_xref="GeneID:5318654"
     CDS             complement(1522703..1523929)
                     /locus_tag="Smed_5005"
                     /note="PFAM: FAD-dependent pyridine nucleotide-disulphide
                     oxidoreductase;
                     KEGG: sme:SMb20820 putative ferredoxin reductase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent pyridine nucleotide-disulfide
                     oxidoreductase"
                     /protein_id="YP_001313719.1"
                     /db_xref="GI:150377123"
                     /db_xref="InterPro:IPR000103"
                     /db_xref="InterPro:IPR001100"
                     /db_xref="InterPro:IPR001327"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="GeneID:5318654"
                     /translation="MRQIVIVGAGECGARAAFALREKGFDGEITLIGAEPLLPYERPP
                     LSKDGLAAAAAPKFVAAPERYREAKIAVLTGTAVEAIGRARKTVTLSDGRSFAYDRLL
                     LATGARPRALPGMPGNSARIRMLRTHADALTIRAALAPGLKLAIIGGGFIGLELAATA
                     RRLGAEVVLVEGQPRILSRGVPEEIAAVVAERHRQEGVEIICGAGIAAIEEGADGASL
                     LLAVGGRIDADLVVVGVGAVPNSELAEAAGLMIDNGIAVDERLCTSDPDILAAGDCCS
                     FPLSHYGGRRVRLEAWRNAQDQGALAAANLMGAGEHIASVPWFWSDQYELTLQISGLA
                     EGTAATVRRELEEGAFILFHLDGEGRLIAASGIGPGNAVARDIRLAEMLIAAGAKPDP
                     QALASPEIRLKKLLAA"
     misc_feature    complement(1522730..1523926)
                     /locus_tag="Smed_5005"
                     /note="phenylpropionate dioxygenase ferredoxin reductase
                     subunit; Provisional; Region: PRK09754"
                     /db_xref="CDD:170080"
     misc_feature    complement(<1523345..1523503)
                     /locus_tag="Smed_5005"
                     /note="Pyridine nucleotide-disulphide oxidoreductase;
                     Region: Pyr_redox; pfam00070"
                     /db_xref="CDD:215691"
     gene            complement(1524279..1524596)
                     /locus_tag="Smed_5006"
                     /db_xref="GeneID:5318655"
     CDS             complement(1524279..1524596)
                     /locus_tag="Smed_5006"
                     /note="TIGRFAM: Rieske [2Fe-2S] domain protein, MocE
                     subfamily;
                     PFAM: Rieske [2Fe-2S] domain protein;
                     KEGG: sme:SMb20819 putative ferredoxin of the Rieseke type
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Rieske (2Fe-2S) domain-containing protein"
                     /protein_id="YP_001313720.1"
                     /db_xref="GI:150377124"
                     /db_xref="InterPro:IPR005806"
                     /db_xref="InterPro:IPR012747"
                     /db_xref="GeneID:5318655"
                     /translation="MSSNWVEVCAADEIDEEDVIRFDHEGRTFAVYRSPDDEYFATDG
                     LCTHEQIHLADGLVMDDIIECPKHNGRFNYKTGQAKGAPVCVNLRTYPVKVEAGSVFI
                     GLS"
     misc_feature    complement(1524291..1524584)
                     /locus_tag="Smed_5006"
                     /note="Rieske non-heme iron oxygenase (RO) family, Rieske
                     ferredoxin component; composed of the Rieske ferredoxin
                     component of some three-component RO systems including
                     biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase
                     (CARDO). The RO family comprise a...; Region:
                     Rieske_RO_ferredoxin; cd03528"
                     /db_xref="CDD:239604"
     misc_feature    complement(order(1524393..1524395,1524402..1524404,
                     1524453..1524455,1524459..1524461))
                     /locus_tag="Smed_5006"
                     /note="[2Fe-2S] cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239604"
     gene            complement(1524637..1525728)
                     /locus_tag="Smed_5007"
                     /db_xref="GeneID:5318656"
     CDS             complement(1524637..1525728)
                     /locus_tag="Smed_5007"
                     /note="PFAM: fatty acid desaturase;
                     KEGG: sme:SMb20818 putative hydrocarbon oxygenase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid desaturase"
                     /protein_id="YP_001313721.1"
                     /db_xref="GI:150377125"
                     /db_xref="InterPro:IPR005804"
                     /db_xref="InterPro:IPR010257"
                     /db_xref="GeneID:5318656"
                     /translation="MTTVPTKRDYSLLGRDAEAAVASGLAAAEWYHTEIPRKQMKELM
                     KREDGPAIRDTAIWLGSLVLLGGFGIYFWGSLWAVPFFLAYGVLYGSASDSRWHECGH
                     GTAFKTMWMNDVVYQIACFMIMRNPVTWRWSHTRHHTDTVIVGRDPEIAVMRPPDLLR
                     LVLNIFGIIDVWHAVVDMVRNAFGVISAAEKTFIPETEQPKAIRVARIWLAIYLATIG
                     LSLYLGSILPLVLIGLPRLYGAWHHIMTGLLQHGGLADNVTDHRLNSRTVYMNPVSRF
                     VYWNMNYHVEHHMFPMVPYHALPRLHAMIRHDLPAANPSILHGYREMIPAFLRQLRNE
                     DYFLKRELPPTARPYREELHNDRLVSAAE"
     misc_feature    complement(1524661..1525644)
                     /locus_tag="Smed_5007"
                     /note="Fatty acid desaturase [Lipid metabolism]; Region:
                     DesA; COG3239"
                     /db_xref="CDD:225779"
     misc_feature    complement(1524766..1525626)
                     /locus_tag="Smed_5007"
                     /note="This CD includes the putative hydrocarbon
                     oxygenase, MocD, a bacterial rhizopine
                     (3-O-methyl-scyllo-inosamine, 3-O-MSI) oxygenase, and
                     other related proteins. It has been proposed that MocD,
                     MocE (Rieske-like ferredoxin), and MocF (ferredoxin
                     reductase)...; Region: Rhizopine-oxygenase-like; cd03511"
                     /db_xref="CDD:239588"
     misc_feature    complement(order(1524865..1524870,1524877..1524879,
                     1525315..1525320,1525327..1525329,1525423..1525425,
                     1525435..1525437))
                     /locus_tag="Smed_5007"
                     /note="putative di-iron ligands [ion binding]; other site"
                     /db_xref="CDD:239588"
     gene            1525936..1526967
                     /locus_tag="Smed_5008"
                     /db_xref="GeneID:5318657"
     CDS             1525936..1526967
                     /locus_tag="Smed_5008"
                     /note="PFAM: regulatory protein LacI;
                     KEGG: sme:SMb20817 putative transcriptional regulator,
                     LacI family protein"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein LacI"
                     /protein_id="YP_001313722.1"
                     /db_xref="GI:150377126"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="GeneID:5318657"
                     /translation="MTRRPTIADLARASGVSVATVDRVLNGRHPVREETARRVYDAAK
                     AIGYHAVGLLRQRVFEDLPQFRLGFLLQKPEQSFYKALAKEIENAALAVTHVRAVPQV
                     DFVASSTPQGIIEKLKAMAARNQAIALVSPDYPAVTAAVEDLRDRGIPVVALLSDFAA
                     GVREAYVGLNNQKVGRTAAWMIAKAAKRPGKVAAFVGSHRFHGHELREIGFRSYFREN
                     APEFEVLDTMVNLDTPEITHEATLDLLQRHPDVLGFYVCGGGMEGAISAIREERLEGK
                     LLVVVNELTPESRAALADETLLMAISTPASALARESVSLMIGAIDREAASVPGQTFLP
                     FDIYTPENI"
     misc_feature    1525957..1526964
                     /locus_tag="Smed_5008"
                     /note="ABC-type sugar transport system, periplasmic
                     component [Carbohydrate transport and metabolism]; Region:
                     RbsB; COG1879"
                     /db_xref="CDD:224791"
     misc_feature    1525957..>1526082
                     /locus_tag="Smed_5008"
                     /note="Helix-turn-helix (HTH) DNA binding domain of the
                     LacI family of transcriptional regulators; Region:
                     HTH_LacI; cd01392"
                     /db_xref="CDD:143331"
     misc_feature    order(1525957..1525959,1525981..1525995,1525999..1526004,
                     1526011..1526013,1526026..1526031,1526038..1526040,
                     1526077..1526079)
                     /locus_tag="Smed_5008"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     misc_feature    1526131..1526955
                     /locus_tag="Smed_5008"
                     /note="Periplasmic sugar-binding domain of uncharacterized
                     transport systems; Region:
                     PBP1_uncharacterized_sugar_binding; cd06307"
                     /db_xref="CDD:107302"
     misc_feature    order(1526167..1526169,1526398..1526400,1526554..1526556,
                     1526782..1526784,1526842..1526844)
                     /locus_tag="Smed_5008"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:107302"
     gene            1527046..1530087
                     /locus_tag="Smed_5009"
                     /db_xref="GeneID:5318658"
     CDS             1527046..1530087
                     /locus_tag="Smed_5009"
                     /note="PFAM: AsmA family protein;
                     KEGG: sme:SMb20815 putative protein, similar to protein
                     involved in assembly of outer membrane proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="YP_001313723.1"
                     /db_xref="GI:150377127"
                     /db_xref="InterPro:IPR007844"
                     /db_xref="GeneID:5318658"
                     /translation="MRRVILCVLGAAALAVTAIAILPSLISSDWMRAELGRQLSSATG
                     SSIAFNGPVKFSAFPSLAVVAKDVTLSAEAQGVTAEFAEVTGSVAFSSLWADRLRIEE
                     ISVDRPVIILDEKAADETTPVQEGSGEARSSDPLPDLAALLERSAIDSVSITSGTFIR
                     RSAARREEVVSDVELTLSIPDIDDTFSLSASARMGELTYEASFTISTLRSLLGRQPAD
                     LDLTVEADPAPAPGLTSLSASGQVTLNANGSYQIRGGKVETGEQAFGLNALFVPGKRA
                     RFLADLDADRLDLTPFVDTTPAASPSKVLSTGTKTDAGNRVGLQFLASFDADVSINAA
                     AITFGEMSASDVSVSAELKDGNLAVELGQLGIDAGVVTADVATDVRSGDPVFRGRLSS
                     EGLDIGSLSALADRSVPVSGALTIDADFAFRGLDADSIRKTIDLTGTVGLRDASFALP
                     LADEAMQEVKAKKISARIESLRKPVRLEGRLEWRNKPVDVDLQIPAADTLLTGDLASQ
                     GIPLKLQMQMPDARLSLDGRAALPGTYAGRLDFSVADLSAFLSGFGQSGAESIGPLAF
                     SGNVVSGAHGVSFDKASVSVNGIEAKGNGSVEFATPLKIETSLDFAELDLARLAGAGA
                     PAPQPKAKAKAKAVIGADVPLDLSSLRSVDATIGINAEKLGYGRVFAGPVTTMLVVSE
                     GVASLTLPESPFYGGHVVASLKADGSQPEPSIAFQASISRASSAPLLTDMAGFRYLEG
                     ALNARFDVTGAGGTTKTLAKSLQGTAEVTFADGAIRGIDIADVYNNLVRLMSSGFKQD
                     DSKATTFTELGASFAIEGGVARTEDIKLVGPLVRMTGKGAADLAQSTLNFRLEPRIVA
                     SLQGQGAEISTDGVGVPVVVEGSFAAPRIYPDLSDLLKNPDAALAKLKDFGLPIDKLP
                     IGDLLNGDGAGAAVKDLLGGTLDEALKDKAFKQEEQQLSIEEIIGGDPAPKPDEAAAE
                     VPPNEEAAKADAPTEQPANGTEEPSEEADGPMEGFFKQLLR"
     sig_peptide     1527046..1527108
                     /locus_tag="Smed_5009"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.994) with cleavage site probability 0.682 at
                     residue 21"
     misc_feature    1527112..>1528356
                     /locus_tag="Smed_5009"
                     /note="Uncharacterized protein involved in outer membrane
                     biogenesis [Cell envelope biogenesis, outer membrane];
                     Region: AsmA; COG2982"
                     /db_xref="CDD:225529"
     misc_feature    1528075..>1528389
                     /locus_tag="Smed_5009"
                     /note="AsmA-like C-terminal region; Region: AsmA_2;
                     pfam13502"
                     /db_xref="CDD:222180"
     misc_feature    1528411..1530084
                     /locus_tag="Smed_5009"
                     /note="Uncharacterized protein involved in outer membrane
                     biogenesis [Cell envelope biogenesis, outer membrane];
                     Region: AsmA; COG2982"
                     /db_xref="CDD:225529"
     misc_feature    1529059..1529697
                     /locus_tag="Smed_5009"
                     /note="AsmA-like C-terminal region; Region: AsmA_2;
                     pfam13502"
                     /db_xref="CDD:222180"
     gene            complement(1530138..1530878)
                     /locus_tag="Smed_5010"
                     /db_xref="GeneID:5318659"
     CDS             complement(1530138..1530878)
                     /locus_tag="Smed_5010"
                     /note="KEGG: sme:SMb20814 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313724.1"
                     /db_xref="GI:150377128"
                     /db_xref="GeneID:5318659"
                     /translation="MIISHRHKFIFIHVPKTAGSTVSAYLAREFGPWDLQLGSWKDAL
                     GNGAKANRLALIAMFCHLSPLKIAQTLIRNHSVDSLAGLALSRRFAGRLADHSSASEI
                     EAFDPSAWKHYFKFCFVRNPFERAVSLYNWHYRKADTRPSFSQMLCLIEAGAAEKERI
                     NWKSWQLYTKNDEVVVDFVGRQERLSEDLRHVCDRLGLPFDERFLTRAKANPRRPDIR
                     SYYKPGDRERVERLFGAEIEHFKYRFPD"
     misc_feature    complement(1530153..1530869)
                     /locus_tag="Smed_5010"
                     /note="Sulfotransferase family; Region: Sulfotransfer_2;
                     pfam03567"
                     /db_xref="CDD:217617"
     gene            complement(1531199..1533004)
                     /locus_tag="Smed_5011"
                     /db_xref="GeneID:5318750"
     CDS             complement(1531199..1533004)
                     /locus_tag="Smed_5011"
                     /note="PFAM: ABC transporter transmembrane region; ABC
                     transporter related;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb20813 putative lipid A + LPS core exporting
                     ABC transporter protein, consisting of ATP-binding and
                     permease domains"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313725.1"
                     /db_xref="GI:150377129"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="GeneID:5318750"
                     /translation="MNVKDRKEREVDTETITGILRRVIAENGRDHIRGYAFAIACLMV
                     VAATTAFTAWVSETVVNEAFANKRGDVVLFVCFSIFAAFVLRGLATYGQAVALSKIGN
                     SIVASYKRRLYTHLMALSIGFFQEKRSAHLTAKINQNISGIRDVLNMTVTSVARDVLT
                     LVGLVGVMISKDWLLSLITFLGAPPLLLGLRYISRRLRLATREAVEANSRVLGAMQET
                     IQGISIVKAFTMEDELGRKVEGIIKGAENRANRIARLSERTAPLTETFAGLAISGVLA
                     YAAFRTIYSNVAPGALFAFVTALLLAYDPVRRLARLQVSLERAAVNARMLYEILDTVP
                     HQRDLPGASRLAITEATVEFRHVRFSYGDGEEVLKGVSFLAEGGKTTALVGPSGAGKS
                     TIISLIPRFYDPQTGVILIDGQDIAAVTKQSLRNGLAYVSQQAYLFEGSIRDNIRYGR
                     PEATDAQVEEAARLAYAHDFILAQPQGYDTPVGEQGMTLSGGQRQRLSIARALVRNAP
                     ILLLDEATSALDTESEAAVQKALDQAMSGRTVIVIAHRLSTVVNADKIVVMNEGLVVE
                     EGTHEELARRPDGVYARLHNIQGGFLELTAGADAT"
     misc_feature    complement(1531232..1532908)
                     /locus_tag="Smed_5011"
                     /note="ABC-type multidrug transport system, ATPase and
                     permease components [Defense mechanisms]; Region: MdlB;
                     COG1132"
                     /db_xref="CDD:224055"
     misc_feature    complement(1532135..1532785)
                     /locus_tag="Smed_5011"
                     /note="ABC transporter transmembrane region; Region:
                     ABC_membrane; pfam00664"
                     /db_xref="CDD:216049"
     misc_feature    complement(1531250..1531951)
                     /locus_tag="Smed_5011"
                     /note="ATP-binding cassette domain of the bacterial lipid
                     flippase and related proteins, subfamily C; Region:
                     ABCC_MsbA; cd03251"
                     /db_xref="CDD:213218"
     misc_feature    complement(1531829..1531852)
                     /locus_tag="Smed_5011"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(order(1531370..1531372,1531463..1531468,
                     1531706..1531708,1531826..1531834,1531838..1531843))
                     /locus_tag="Smed_5011"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(1531706..1531717)
                     /locus_tag="Smed_5011"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(1531511..1531540)
                     /locus_tag="Smed_5011"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(1531463..1531480)
                     /locus_tag="Smed_5011"
                     /note="Walker B; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(1531445..1531456)
                     /locus_tag="Smed_5011"
                     /note="D-loop; other site"
                     /db_xref="CDD:213218"
     misc_feature    complement(1531364..1531384)
                     /locus_tag="Smed_5011"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213218"
     gene            1533461..1534639
                     /locus_tag="Smed_5012"
                     /db_xref="GeneID:5318751"
     CDS             1533461..1534639
                     /locus_tag="Smed_5012"
                     /note="KEGG: sme:SMb20812 conserved hypothetical protein,
                     possibly membrane-anchored"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313726.1"
                     /db_xref="GI:150377130"
                     /db_xref="GeneID:5318751"
                     /translation="MADKRYSDARTICREHISTGDPSGFWRHYESFVDELASSCRQQE
                     VSGSRIKIALFNDTDFRINIGCRLTSQGLKQQILDAFPAAEITSIGFNFAAFRKEFPN
                     STSAGGYELSDIETRLSTAYGEDAVDHITAADFVILQPEGSLDHRTTAEGLATFFTPI
                     LTARKLGKPFAVLNGTIPIYEGERSDYLKGLFRELGHVAARDEISAEYYGIEFLADAA
                     FLRISPAPVADRDGCLITTGARNNAEEDVEILKAALKICEAWKLRPVVLTHAVERFSP
                     YEAEIIDRGGIFAETASIERAAETISTCRLHIGGRYHMAIFSLLCNVPSLLFDVKTHK
                     NQWLERYSPLITLVHPHTDLDAAAAAVLSGGVSQGHPASTGAEKYGLFLKRAMAEQPL
                     "
     misc_feature    1533647..1534453
                     /locus_tag="Smed_5012"
                     /note="Polysaccharide pyruvyl transferase; Region:
                     PS_pyruv_trans; pfam04230"
                     /db_xref="CDD:217977"
     gene            complement(1534694..1534990)
                     /locus_tag="Smed_5013"
                     /db_xref="GeneID:5318752"
     CDS             complement(1534694..1534990)
                     /locus_tag="Smed_5013"
                     /note="KEGG: sme:SMb20811 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313727.1"
                     /db_xref="GI:150377131"
                     /db_xref="GeneID:5318752"
                     /translation="MHFEDDGLRVATLEFLVKVLATQRLRDDPDADLKQGVLSAFERI
                     PLQFVCSEVERAEIRAKMHAEANAILNWAVEGRTTTISPIAVRPLSASHYRQWR"
     gene            complement(1535151..1537238)
                     /locus_tag="Smed_5014"
                     /db_xref="GeneID:5318753"
     CDS             complement(1535151..1537238)
                     /locus_tag="Smed_5014"
                     /note="PFAM: acyltransferase 3;
                     KEGG: sme:SMb20810 putative membrane-located cell surface
                     saccharide saccharide acetylase protein"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase 3"
                     /protein_id="YP_001313728.1"
                     /db_xref="GI:150377132"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="GeneID:5318753"
                     /translation="MIEGGLKTPLWLWQSITEMGTRLAVIHRDFDYRPDLDGLRAVAI
                     LPVLLFHAGFSSFSGGFVGVDVFFVLSGFFMARIILTDLERGSFSFASFYLRRMRRIF
                     PALFSMIAVSVVAAWFLLMPQEFRYFGDSVQAAALFTSNILFRSESGYFDLSSEMKPL
                     LHTWSLSVEEQFYLIFPVAVFLAFKFARGHIRAIVLAVALLSFGASTWGIVHSPEKAF
                     YLLHFRVWELLIGVLVAIAPISAYGHRGSQALAALGLLVVLLAVFLYSPDMPFPGIYA
                     AVPCLGTALVIHAHCRGGAIGRLLGNPVSVFIGRISYSLYLWHWPIIVYLRYGLGHEL
                     TTGWALTAVAMSFALAYISWRLVEQPARYGVLASSRVAIVGVSSAAISFAVAFGFIVN
                     DLEGIPQRLPEKARTLYQATYDESPFSSKRCFTDSNGEGLTPVQIRRGKICRVGVETA
                     GEPRFLVWGDSHAAAIAPAIDLAARQLGISGMFVGRGSCPPLPDTDFAPPGAVKRCVD
                     HNSAVMSLIEKRKFAFVFMVGYWPKYVHREELPGQGIFFDPGVAPSRTDWSIPVRKGL
                     DATLTKLAGQGSKAILVMDVPEMGFDVPEALARAAASGRSLDIAPSVEYTNRRQALAR
                     RVLADAAKLSGALVVDPMSEICDASRCHVMRKGTVLYKDGDHLSAKGAESLSALFRPV
                     LSMMRDSVQAASR"
     misc_feature    complement(1536150..1537184)
                     /locus_tag="Smed_5014"
                     /note="Predicted acyltransferases [Lipid metabolism];
                     Region: COG1835"
                     /db_xref="CDD:224748"
     gene            complement(1537297..1538286)
                     /locus_tag="Smed_5015"
                     /db_xref="GeneID:5318754"
     CDS             complement(1537297..1538286)
                     /locus_tag="Smed_5015"
                     /EC_number="5.3.1.13"
                     /note="TIGRFAM: KpsF/GutQ family protein;
                     PFAM: CBS domain containing protein; sugar isomerase
                     (SIS);
                     KEGG: sme:SMb20809 putative protein involved in assembly,
                     operation or regulation of an export machinery for a cell
                     surface saccharide"
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family protein"
                     /protein_id="YP_001313729.1"
                     /db_xref="GI:150377133"
                     /db_xref="InterPro:IPR000638"
                     /db_xref="InterPro:IPR000644"
                     /db_xref="InterPro:IPR001199"
                     /db_xref="InterPro:IPR001347"
                     /db_xref="InterPro:IPR004800"
                     /db_xref="InterPro:IPR006025"
                     /db_xref="GeneID:5318754"
                     /translation="MNVVVSDPILASISRTIATAADGIHALAACLEENAALRRSFVDA
                     IELVASKRGRVVVAGVGKSGHIGRKIAATLASTGTSAYFVHPTEASHGDLGMITAEDL
                     LILLSWSGETVELGNVLTYAKRFNVPVISVTSNADSTIARNSTIPVILPKVPEACPHG
                     LAPTTSAILQLAVGDAFAIALLERRGFSAEDFKTFHPGGKLGSQLLLAHELAHSGEAV
                     PLLPIGSPMSEAVIQMSCKGFGVVGVVGGDGELVGVITDGDLRRHMSQNLLLLTVETV
                     MSHMPRVITPGMLASAAMEMMQSQKITVLFLVDDVGRPSGILHVHDLLRAGVA"
     misc_feature    complement(1537330..1538094)
                     /locus_tag="Smed_5015"
                     /note="KpsF/GutQ family protein; Region: kpsF; TIGR00393"
                     /db_xref="CDD:129488"
     misc_feature    complement(1537747..1538094)
                     /locus_tag="Smed_5015"
                     /note="KpsF-like protein. KpsF is an arabinose-5-phosphate
                     isomerase which contains SIS (Sugar ISomerase) domains.
                     SIS domains are found in many phosphosugar isomerases and
                     phosphosugar binding proteins. KpsF catalyzes the
                     reversible reaction of ribulose...; Region: SIS_Kpsf;
                     cd05014"
                     /db_xref="CDD:240145"
     misc_feature    complement(1537966..1537968)
                     /locus_tag="Smed_5015"
                     /note="putative active site [active]"
                     /db_xref="CDD:240145"
     misc_feature    complement(1537309..1537644)
                     /locus_tag="Smed_5015"
                     /note="This cd contains two tandem repeats of the
                     cystathionine beta-synthase (CBS pair) domains associated
                     with KpsF/GutQ domains in the API [A5P (D-arabinose
                     5-phosphate) isomerase] protein.  These APIs catalyze the
                     conversion of the pentose pathway...; Region:
                     CBS_pair_KpsF_GutQ_assoc; cd04604"
                     /db_xref="CDD:239977"
     gene            1538563..1539300
                     /locus_tag="Smed_5016"
                     /db_xref="GeneID:5318755"
     CDS             1538563..1539300
                     /locus_tag="Smed_5016"
                     /note="KEGG: sme:SMb20808 putative membrane-anchored
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane-anchored protein"
                     /protein_id="YP_001313730.1"
                     /db_xref="GI:150377134"
                     /db_xref="GeneID:5318755"
                     /translation="MTIEPEALEKLREKHRRWLSRLGIVDKPWLILGSAPSPTIPPDL
                     IGHCARVDVNNAGKTANALGLPPADLTFRKRKKSWEEHPYVRTRGLLWLHTKSIWVMY
                     LKLLAMPQVRYKSLMRATKAEREAIVNVVSGGLPSDIGEVGKVTNGVAALCYALFMGV
                     PSVTLAGFSVTKMGHSYDDKGRIRRQIAEDTFVLRRLRDRGNVFTTELELSEHIGLPF
                     IRDREDIIRNMGGAIGANPAQWKSAQI"
     gene            complement(1539276..1540769)
                     /locus_tag="Smed_5017"
                     /db_xref="GeneID:5318756"
     CDS             complement(1539276..1540769)
                     /locus_tag="Smed_5017"
                     /note="PFAM: glycosyl transferase family 39;
                     KEGG: sme:SMb20807 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family protein"
                     /protein_id="YP_001313731.1"
                     /db_xref="GI:150377135"
                     /db_xref="InterPro:IPR003342"
                     /db_xref="GeneID:5318756"
                     /translation="MRSLLVRRPDLLYVLIAGYCLLSVILKVLRPDSLEIDESEQALL
                     SQYLLLGYGGQPPFYNWLQYGVVALFGISVASLAILKNGLLFLFLLLYGLTARLLSSS
                     PLAPAVAVLGVLTLPPVFLLSQRDLSHTVAALFAVSLFLYGFFRALKNPPKVGHYLLV
                     GVAVGLGAISKYNFVILPLAALLAILPEAKLRKYLFDWRVLASVAVCAVIVAPHAYWV
                     VNNLGHATGVTVAEMKEGADSALLPHAIQGLVSLAVAALKGVALTFAVFGLIFYADVG
                     KILCAESLWTRVVGRMIVACFLMIAFIVVAMDATHIRAKWLALFTALLPLYLTLKIDA
                     AGLDPARRLPAFFSISGILSVGVIVMLWARVFVGPMIGDYSFAHTPYSGFARMVRADP
                     GPPRVAIVVDDRIVAGNLRIQFPDTPIILTGFSQEAERHLPPGRILAAWSAEGKRRAE
                     IPPRITGLLQLMPVRIADAKPTIVSVPYNAGRPGDTYTFAYIWADFH"
     misc_feature    complement(1539279..1540760)
                     /locus_tag="Smed_5017"
                     /note="4-amino-4-deoxy-L-arabinose transferase and related
                     glycosyltransferases of PMT family [Cell envelope
                     biogenesis, outer membrane]; Region: ArnT; COG1807"
                     /db_xref="CDD:224720"
     misc_feature    complement(1540119..1540604)
                     /locus_tag="Smed_5017"
                     /note="Dolichyl-phosphate-mannose-protein
                     mannosyltransferase; Region: PMT_2; pfam13231"
                     /db_xref="CDD:221995"
     gene            1541046..1541735
                     /locus_tag="Smed_5018"
                     /db_xref="GeneID:5318757"
     CDS             1541046..1541735
                     /locus_tag="Smed_5018"
                     /note="KEGG: sme:SMb20806 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313732.1"
                     /db_xref="GI:150377136"
                     /db_xref="GeneID:5318757"
                     /translation="MTQGAHIYIGFDSKEVVAYHVLCQSILEKSSIPVTFTPISLNNV
                     ENIFTRERNPLQSTEFSFSRFLVPYLSRYEGWSLFADCDMLMRTDIAQLWELRDDRYA
                     AMCVKHDYIPKVETKFLGQVQTKYEKKNWSSVILFNNAKCRKLDLDYVNTASGLELHQ
                     FKWLDSDDLIGELPASWNWLVNEYEYSPDAKLVHFTDGGPYFDEYKNDDYAEEWFATR
                     DRVLHVTQRSA"
     misc_feature    1541061..1541633
                     /locus_tag="Smed_5018"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; Region: Glyco_tranf_GTA_type;
                     cl11394"
                     /db_xref="CDD:245596"
     misc_feature    order(1541076..1541078,1541286..1541288,1541292..1541294)
                     /locus_tag="Smed_5018"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            complement(1541863..1542768)
                     /locus_tag="Smed_5019"
                     /db_xref="GeneID:5318758"
     CDS             complement(1541863..1542768)
                     /locus_tag="Smed_5019"
                     /note="KEGG: sme:SMb20805 putative glycosyltransferase
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="YP_001313733.1"
                     /db_xref="GI:150377137"
                     /db_xref="GeneID:5318758"
                     /translation="MISNRPFSRSCIKIAVRLLLGRSRAHVQDWFPGLKLELAPADRD
                     GTIQYRGELVGRLTSPLRALEEKPANVLIVGSGPSVARCDLTRADGSSCLLLNGALHL
                     FPSVIAKPLAIAIEDERFIWRHFDLVKRIPAGCVCLMSVSVIRAICELDRTWLRDRPI
                     VLIDNVRKPYGVARRDTADLRKLPYVRLSEDGDVGFSEDPFAGIFQAGSVAVSAAQFA
                     VAWRPRSIGFVGIDLSNADEPRYYETTDKAYSGIVAAQKRIVDHLIMTRNIAAESGIE
                     VVNHSPISALVGMGFGYDATFAKAE"
     gene            complement(1542827..1543558)
                     /locus_tag="Smed_5020"
                     /db_xref="GeneID:5318759"
     CDS             complement(1542827..1543558)
                     /locus_tag="Smed_5020"
                     /note="KEGG: sme:SMb20804 putative membrane-anchored
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane-anchored protein"
                     /protein_id="YP_001313734.1"
                     /db_xref="GI:150377138"
                     /db_xref="GeneID:5318759"
                     /translation="MGSWISDARKRIYRNLKYRIMRPDPPAAPFRFNSPVVVVGSAPV
                     SNRPAGFDESFRIITVNGSQSVIAKWGVDAPDITMMMFNQVEGTTANAIEVRRVLKGQ
                     RTGTLYVFLWRKDDRARLEEGLRAFDYKYDRLEIVDRYERMALLDRVAELRSLEMDAD
                     SKCSNGMNAVLFALYNGAPAVIVTGINPNSSGHVYNSTGLTRLHVQMDKFLVSKLISE
                     GHPIFTADPPVSEELGIPLWSGSNR"
     gene            complement(1543601..1544431)
                     /locus_tag="Smed_5021"
                     /db_xref="GeneID:5318760"
     CDS             complement(1543601..1544431)
                     /locus_tag="Smed_5021"
                     /note="KEGG: sme:SMb20803 probable
                     3-deoxy-manno-octulosonate cytidylyltransferase (CMP KDO
                     transferase) protein"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-D-manno-octulosonate
                     cytidylyltransferase"
                     /protein_id="YP_001313735.1"
                     /db_xref="GI:150377139"
                     /db_xref="GeneID:5318760"
                     /translation="MDFPASGTTENLTTAEQWRALFSRYSHVILVANSDQVNVKELQA
                     EYPPTALFVFFNKVYKVLDEQFSGHSLLISRAQPGGANIVYRQEVADVVKLFAPQAFL
                     GIMNIRLAASERLNTSSDYLGTPTGHLDLTGFCADFYPQAKVPTSGFAIALWLVDQAL
                     PAKIILAGFSAKRSEKWRVVAVHDWTFEQVFLRLFERVDKLTMRGGIATNSYASLASR
                     FPELPAAEISSTIAEVLSSRLNQTDAQVDKLISLTNVLRSTDEFLRRLKPKFLKKTKA
                     "
     gene            1544662..1545576
                     /locus_tag="Smed_5022"
                     /db_xref="GeneID:5318770"
     CDS             1544662..1545576
                     /locus_tag="Smed_5022"
                     /note="PFAM: protein of unknown function DUF23;
                     KEGG: sme:SMb20563 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313736.1"
                     /db_xref="GI:150377140"
                     /db_xref="InterPro:IPR008166"
                     /db_xref="GeneID:5318770"
                     /translation="MFGLKAKRHLTRELAITPPSGELNRHGIAIVACVKNEASYIAEW
                     VRFHQAVGVRHFHLYDDGSTDGTVELLQRSLTGQELTVVPWKMRMRDEKSGEFLNGQT
                     IAFAHAILNFGGKYERMAFIDVDEFLLPKKGRTLEEALRGASGFPNISLPWHMFGHSG
                     HVSRPAGPVCLNYKMRVSDPMQQNLDASNFKCIVDPVEVTKVGVHHFQTRSYGDETAN
                     DSGMVVPKKKRKAAEFYSAEFLQLNHYYAKSIEELKEKTDRGWSFDGSAEKYRNKVTS
                     TITYIEANAIEDRSMIDFVDQNGIDLGH"
     misc_feature    1544743..>1545087
                     /locus_tag="Smed_5022"
                     /note="Glycosyltransferases involved in cell wall
                     biogenesis [Cell envelope biogenesis, outer membrane];
                     Region: WcaA; COG0463"
                     /db_xref="CDD:223539"
     misc_feature    1544749..1545528
                     /locus_tag="Smed_5022"
                     /note="Glycosyltransferase family 92; Region:
                     Glyco_transf_92; pfam01697"
                     /db_xref="CDD:216651"
     misc_feature    order(1544758..1544760,1544764..1544766,1544836..1544838,
                     1545028..1545030,1545034..1545036)
                     /locus_tag="Smed_5022"
                     /note="active site"
                     /db_xref="CDD:132997"
     gene            1545632..1546603
                     /locus_tag="Smed_5023"
                     /db_xref="GeneID:5318771"
     CDS             1545632..1546603
                     /locus_tag="Smed_5023"
                     /note="KEGG: sme:SMb20562 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313737.1"
                     /db_xref="GI:150377141"
                     /db_xref="GeneID:5318771"
                     /translation="MQDNDDTTVKTSNTSCVWAVAESKAGTLTQCLGVGKQFHREPVV
                     KLISRTRGLRKLFEPRLFRKKEQRPELVISCGFRAEPAVLDIKAAYGGKPVTVHLQRP
                     RIEGYDLVFVSRHDWVDELNRLPNYHSMVGVPHQITWARLAPLRDAARRRFSPDGRPI
                     VAVFVGGSNGAYVYDDRTHQNIKGAIEQLEKEGWRIVVSVSRRSEDHTQQALSTLNSE
                     SIAVWDRRSENPYLDYMAAADAFVIAKDSITMPCEALATGKPVFTLELTHVAGPRLDK
                     FERYHRDLHETLQLTRPFEGKIEPYSYEPLDETRRIASVIRSKLDLQ"
     misc_feature    1545680..1546591
                     /locus_tag="Smed_5023"
                     /note="Predicted nucleoside-diphosphate-sugar epimerase
                     [Cell envelope biogenesis, outer membrane]; Region:
                     COG3660"
                     /db_xref="CDD:226186"
     misc_feature    1545704..1546591
                     /locus_tag="Smed_5023"
                     /note="Mitochondrial fission ELM1; Region: Mito_fiss_Elm1;
                     pfam06258"
                     /db_xref="CDD:218962"
     gene            complement(1546626..1547471)
                     /locus_tag="Smed_5024"
                     /db_xref="GeneID:5318772"
     CDS             complement(1546626..1547471)
                     /locus_tag="Smed_5024"
                     /note="KEGG: sme:SMb20043 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313738.1"
                     /db_xref="GI:150377142"
                     /db_xref="GeneID:5318772"
                     /translation="MTTSVLAASGGVKQVICINWGTKYGAPFINRLYAMVARNITPPF
                     TFTCFTDSRAGLNPAILCEDLPPLDVESMPTNTRGIWPKARLWGPTLGGLKGPVLFLD
                     LDLVIVSSLDVFFDIGEADDIILARNQTTPFERLGQTSLFRFPVGKLVPLQDKFRSDP
                     QSVADEYRYEQRFVSRKAPGGIKFFPRKWVLHFRQDCRWPFPLNYFFAPRLPHDARVV
                     IFPRGLHPQHAVEGRFGTKGPRKTVFEHIAGVFDAKQRKNKGPLQYLRHYIRPTPWVA
                     EHWRE"
     gene            1548029..1548250
                     /locus_tag="Smed_5025"
                     /db_xref="GeneID:5318773"
     CDS             1548029..1548250
                     /locus_tag="Smed_5025"
                     /note="PFAM: Heavy metal transport/detoxification protein;
                     KEGG: sme:SMb20560 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal transport/detoxification protein"
                     /protein_id="YP_001313739.1"
                     /db_xref="GI:150377143"
                     /db_xref="InterPro:IPR006121"
                     /db_xref="GeneID:5318773"
                     /translation="MYHLNVEDMTCGHCVATIEKAVKTVDRNARVAVDLEAKTASIES
                     GVASEAFMAAIEEAGYRASFKKSCCSHVG"
     misc_feature    1548038..1548217
                     /locus_tag="Smed_5025"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1548053..1548061,1548068..1548070)
                     /locus_tag="Smed_5025"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     gene            1548361..1548735
                     /locus_tag="Smed_5026"
                     /db_xref="GeneID:5318774"
     CDS             1548361..1548735
                     /locus_tag="Smed_5026"
                     /note="KEGG: sme:SMa1033 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313740.1"
                     /db_xref="GI:150377144"
                     /db_xref="InterPro:IPR001545"
                     /db_xref="GeneID:5318774"
                     /translation="MFQITLQKMLILARLAIVVSLTAYSLPAASASMHGGWSNTEIAQ
                     SGDHHDETKIGGHSHDDQKSSPDDAKKLVKTECCTGFCVSMAIVAQAGSDRRPRVASI
                     RKFADDARPKGELPPLHRPSSI"
     sig_peptide     1548361..1548453
                     /locus_tag="Smed_5026"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.996) with cleavage site probability 0.894 at
                     residue 31"
     gene            1548828..1549055
                     /locus_tag="Smed_5027"
                     /db_xref="GeneID:5318775"
     CDS             1548828..1549055
                     /locus_tag="Smed_5027"
                     /note="KEGG: sme:SMa1036 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313741.1"
                     /db_xref="GI:150377145"
                     /db_xref="GeneID:5318775"
                     /translation="MKQLFFVAALSLLASGCAATLPPDVIASGDLAASQSQVRPLRYA
                     SPVSGYTHRVPVDPQPWGNRNDAQTPEGDAS"
     sig_peptide     1548828..1548887
                     /locus_tag="Smed_5027"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.404 at
                     residue 20"
     gene            1549052..1550515
                     /locus_tag="Smed_5028"
                     /db_xref="GeneID:5318776"
     CDS             1549052..1550515
                     /locus_tag="Smed_5028"
                     /note="KEGG: sme:SMa1037 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313742.1"
                     /db_xref="GI:150377146"
                     /db_xref="GeneID:5318776"
                     /translation="MMRANVKRAAALALPLVLGGCVSASEYAAKNAGFSAVEAKTAEA
                     VRKQTVWIQNQQHARVVSDRVKTLMAKKAIDVETAVQVALLNNRGLQAAYADLGDSAA
                     DAWQSTMLVNPTVSVGLTGIGTPGLEAFKSVEGMIANNILALATRERDIAIADTRFRQ
                     AQLNAALRTLQLAADTRRAWINAVAAWETVAQLNQAQAAADAASELAQELGKSGALTK
                     EGQAREHVFSAELAGQTAKARLEARLAKEELTRLMGLWGSGIDYQVPNRLPPLPKGIM
                     KRDPIEAEALQRRVDLQMAKLDLEATARSYKLTEATRYVTDLELLTGFETERELEDGD
                     IRSETTGQAELEFVIPIFDSGRARMRKAELAYMRAANLLAEKAVNVRSEARSAYQAYR
                     ANYDIARHYRKSVVPLRTRIAEESLLTYNAMITNTFELLADSREKVNANLLAVNAKRD
                     FWLAEANLAPAVYGGGAGAAAVEIEVAAAAESGGGGH"
     sig_peptide     1549052..1549126
                     /locus_tag="Smed_5028"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.693 at
                     residue 25"
     misc_feature    1549106..1550425
                     /locus_tag="Smed_5028"
                     /note="Outer membrane protein [Cell envelope biogenesis,
                     outer membrane / Intracellular trafficking and secretion];
                     Region: TolC; COG1538"
                     /db_xref="CDD:224455"
     gene            1550530..1551879
                     /locus_tag="Smed_5029"
                     /db_xref="GeneID:5318777"
     CDS             1550530..1551879
                     /locus_tag="Smed_5029"
                     /note="PFAM: multicopper oxidase type 2; multicopper
                     oxidase type 3;
                     KEGG: sme:SMa1038 putative copper-containing oxidase"
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase type 3"
                     /protein_id="YP_001313743.1"
                     /db_xref="GI:150377147"
                     /db_xref="InterPro:IPR002355"
                     /db_xref="InterPro:IPR011706"
                     /db_xref="InterPro:IPR011707"
                     /db_xref="GeneID:5318777"
                     /translation="MFNRRQLLGASAALVSTATWAKSSNMGLPEAAVMETAETQPPLK
                     PTSGPGYNPVVTLNGWTLPYRMNNGVKEFHLVAEPVEREMAEGMTAYLWGYNGQSPGP
                     TIEAVEGDRVRIFVTNKLPEHTTIHWHGMILPSGMDGVGGLSQPHIPVGKTFVYEFDL
                     VKSGTFMYHPHSDEMVQMAMGMMGFFVIHPKDPKFMPVDRDFVFLLNAYDIDPGSYVP
                     RVMEMTDFNMWCWNSRIFPDISPLVVSKNDRVRVRVGNLTMTNHPIHMHGYDFEVTCT
                     DGGWVRPEARWPEVSIDIPVGAMRAYEFDARYEGDWAIHCHKSHHTMNAMGHDIPTFI
                     GVDKSKVAEKIRKLRPEYMPMGTKGMADMGEMEMEIPENTIPMMTGWGPHGPIEMGGM
                     FSVVKVREGISAGDYSDPGWYENPPGTQAWEWTGKLPDAIKAKDAKTQITPKHGNHG"
     misc_feature    1550530..1551510
                     /locus_tag="Smed_5029"
                     /note="Putative multicopper oxidases [Secondary
                     metabolites biosynthesis, transport, and catabolism];
                     Region: SufI; COG2132"
                     /db_xref="CDD:225043"
     sig_peptide     1550530..1550595
                     /locus_tag="Smed_5029"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.999 at
                     residue 22"
     misc_feature    1550788..1551108
                     /locus_tag="Smed_5029"
                     /note="Multicopper oxidase; Region: Cu-oxidase_3;
                     pfam07732"
                     /db_xref="CDD:219542"
     misc_feature    1551163..1551507
                     /locus_tag="Smed_5029"
                     /note="Multicopper oxidase; Region: Cu-oxidase_2;
                     pfam07731"
                     /db_xref="CDD:219541"
     gene            1551919..1552398
                     /locus_tag="Smed_5030"
                     /db_xref="GeneID:5318778"
     CDS             1551919..1552398
                     /locus_tag="Smed_5030"
                     /note="PFAM: blue (type 1) copper domain protein;
                     KEGG: sme:SMa1041 putative copper oxidase, possibly
                     exported"
                     /codon_start=1
                     /transl_table=11
                     /product="blue (type1) copper domain-containing protein"
                     /protein_id="YP_001313744.1"
                     /db_xref="GI:150377148"
                     /db_xref="InterPro:IPR000923"
                     /db_xref="InterPro:IPR002355"
                     /db_xref="InterPro:IPR011572"
                     /db_xref="GeneID:5318778"
                     /translation="MKAHIFGLLVAALATPALASGSHEGGHGEAMAVGEPGKKASATR
                     TIEVTMKETDDGRMIFTPSTFKVSKGQTIRFAIKNAGGLDHEFVLDQEDKIMEHKAVM
                     EKFPEMEHDDPNAIRLAAGESGEIIWKFTNDGTFKIACLVPGHYDVGMHGDVTVAKK"
     misc_feature    1551919..1552392
                     /locus_tag="Smed_5030"
                     /note="Uncharacterized copper-binding protein [Inorganic
                     ion transport and metabolism]; Region: COG4454"
                     /db_xref="CDD:226861"
     sig_peptide     1551919..1551978
                     /locus_tag="Smed_5030"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.986 at
                     residue 20"
     gene            1552418..1552702
                     /locus_tag="Smed_5031"
                     /db_xref="GeneID:5318779"
     CDS             1552418..1552702
                     /locus_tag="Smed_5031"
                     /note="KEGG: sme:SMa1043 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313745.1"
                     /db_xref="GI:150377149"
                     /db_xref="GeneID:5318779"
                     /translation="MKCLIKLTLATALAVGTAYGALAQEFTKATVKKVDVKAKKVTLI
                     HEELKNLNMPAMTMVFRAQDETMLEKLKEGANVEFVAQRVNGRLTVTEVK"
     sig_peptide     1552418..1552489
                     /locus_tag="Smed_5031"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.959 at
                     residue 24"
     misc_feature    <1552544..1552699
                     /locus_tag="Smed_5031"
                     /note="Copper binding periplasmic protein CusF; Region:
                     CusF_Ec; cl02363"
                     /db_xref="CDD:243005"
     gene            complement(1553015..1554178)
                     /locus_tag="Smed_5032"
                     /db_xref="GeneID:5318780"
     CDS             complement(1553015..1554178)
                     /locus_tag="Smed_5032"
                     /note="PFAM: Hemolysin-type calcium-binding region;
                     KEGG: sme:SMb21229 putative calcium-binding exported
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Hemolysin-type calcium-binding protein"
                     /protein_id="YP_001313746.1"
                     /db_xref="GI:150377150"
                     /db_xref="InterPro:IPR001343"
                     /db_xref="GeneID:5318780"
                     /translation="MILKGTNLADTIRGFLADDVIWGYEGDDYLYGDAGNDRIFGGSG
                     NDFINAGLGNDYAEGGDGNDRLEGGLGDDTLDGGLGNDTFDGGNGNDIVKGGDGHDQI
                     LGGRGHDTIYGGAGEEYIDAGDGDDVIYAGSGNDGFNNRINPATGKLTQQAVGGGAGN
                     DTIYGEEGNDALKGQAGNDKVYGGIGDDIVDGGNGDNFLDGGDGNDVLDSEGGIDVAY
                     GGVGKDKIAVGAGNDLAYGDDGDDILSGEAGADILHGGNGNDLIYGGNGNDIVRGDAG
                     KDTLVGEAGSDILWGGADSDRFVFKGTPTLSGQDSVMDFQDGFDILVIENLGVTRYSS
                     SGANGTVFAYDTTGGDVLIKGNDSVGRVFSILVDDPIGTLSAAQFSKADFLFA"
     misc_feature    complement(<1553219..>1553524)
                     /locus_tag="Smed_5032"
                     /note="Peptidase M10 serralysin C terminal; Region:
                     Peptidase_M10_C; pfam08548"
                     /db_xref="CDD:117125"
     gene            1554723..1554854
                     /locus_tag="Smed_5033"
                     /pseudo
                     /db_xref="GeneID:5319082"
     gene            complement(1555250..1555459)
                     /locus_tag="Smed_5034"
                     /db_xref="GeneID:5319083"
     CDS             complement(1555250..1555459)
                     /locus_tag="Smed_5034"
                     /note="KEGG: sme:SMb21035 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="YP_001313747.1"
                     /db_xref="GI:150377151"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="GeneID:5319083"
                     /translation="MLGWSQAELAKAAKVSRQTIADFERGAHVPISNNLTSIITAFQE
                     AGIEFIRENGGGVGVRFKKAMSRGG"
     misc_feature    complement(1555331..1555456)
                     /locus_tag="Smed_5034"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; Region: HTH_XRE; cd00093"
                     /db_xref="CDD:238045"
     misc_feature    complement(order(1555382..1555387,1555397..1555399,
                     1555406..1555408,1555439..1555444))
                     /locus_tag="Smed_5034"
                     /note="sequence-specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238045"
     misc_feature    complement(1555388..1555390)
                     /locus_tag="Smed_5034"
                     /note="salt bridge; other site"
                     /db_xref="CDD:238045"
     gene            1555624..1556202
                     /locus_tag="Smed_5035"
                     /db_xref="GeneID:5319084"
     CDS             1555624..1556202
                     /locus_tag="Smed_5035"
                     /note="KEGG: sme:SMb21036 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313748.1"
                     /db_xref="GI:150377152"
                     /db_xref="GeneID:5319084"
                     /translation="MADSDNSRTLPAVTRGDFHSFVAASLTSDPEPSRLLDASPDACD
                     DDPALEVWREWCVARERLVQSCVKQQRLETKLFATVGSRLTAPEAWKAADKEIGYSEA
                     VEAEGRAATAEGIVADTLWKTPAQSLAGATAKLHAIVSKWQPSVTSDEYPWPQLRAVI
                     ADLLKIDAEMSFHRNGLHRLAVPETHGASRGG"
     gene            complement(1556260..1556478)
                     /locus_tag="Smed_5036"
                     /db_xref="GeneID:5319085"
     CDS             complement(1556260..1556478)
                     /locus_tag="Smed_5036"
                     /note="PFAM: helix-turn-helix domain protein;
                     KEGG: pde:Pden_3368 transcriptional regulator, XRE family"
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="YP_001313749.1"
                     /db_xref="GI:150377153"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="GeneID:5319085"
                     /translation="MKVRETVARNLRIARNDRQLSQEELGLRANVHRTYIGMLEREEY
                     NPTIEMLEKLAAALDLKVVDFFKTDANQ"
     misc_feature    complement(1556284..1556457)
                     /locus_tag="Smed_5036"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; Region: HTH_XRE; cd00093"
                     /db_xref="CDD:238045"
     misc_feature    complement(order(1556356..1556358,1556431..1556433,
                     1556443..1556445))
                     /locus_tag="Smed_5036"
                     /note="non-specific DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:238045"
     misc_feature    complement(order(1556359..1556361,1556434..1556436))
                     /locus_tag="Smed_5036"
                     /note="salt bridge; other site"
                     /db_xref="CDD:238045"
     misc_feature    complement(order(1556353..1556358,1556368..1556370,
                     1556377..1556379,1556410..1556415))
                     /locus_tag="Smed_5036"
                     /note="sequence-specific DNA binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:238045"
     gene            1556637..1558241
                     /locus_tag="Smed_5037"
                     /db_xref="GeneID:5319086"
     CDS             1556637..1558241
                     /locus_tag="Smed_5037"
                     /note="PFAM: extracellular solute-binding protein family
                     5;
                     KEGG: sme:SMb21037 putative oligopeptidemurein peptide ABC
                     transporter periplasmic solute-binding protein precursor"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="YP_001313750.1"
                     /db_xref="GI:150377154"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="GeneID:5319086"
                     /translation="MQIQSRFCSHRLAALLISLTFWSGLPGPGHAQEELRIATSYKLM
                     TLDPHYANLNENTSLLSHIYERLVYQDDRLDLQPGLAVSWRAVSDRQWEFKLRENVRF
                     HDGSPLTADDVVYTIERIRDFLKSPSGGFRSYLTGIESVSAPDPLTVVINTKGNIPNL
                     PLSFSSIFVMNRPAQGFQTTEELNAGRAGHPPVGTGPYTFESWSSGEVLKLARNDDYW
                     GGRPAWPQVTFRVIESPAARVAALSTGEVDLADAIPARDVASLKQRGARIASVGAARI
                     NFLQFDVERDRLPGVTDKSGEPIANPFKDALVRRALAMATDRGILVDKILSGYGTAAA
                     QLFPGGLPGTSETLQPEAPKYDEAKALLAKAGFPDGFNLILAGPAGRYPGDGESLQAI
                     AQSWARIGVKVQPAAAPFSVFNTKRAAGDYAVWYGGASGEAVDIILHALLASPDPESG
                     NGALNFGHYRNQAFDAMLARAESIQEGPERNKALAEATEFVMADQPIIPLYHFHHIVG
                     YGPRVASYAMHPRGWTTAMQTLAATE"
     sig_peptide     1556637..1556732
                     /locus_tag="Smed_5037"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 1.000 at
                     residue 32"
     misc_feature    1556667..1558205
                     /locus_tag="Smed_5037"
                     /note="ABC-type dipeptide transport system, periplasmic
                     component [Amino acid transport and metabolism]; Region:
                     DdpA; COG0747"
                     /db_xref="CDD:223818"
     misc_feature    1556736..1558175
                     /locus_tag="Smed_5037"
                     /note="The substrate-binding component of an
                     uncharacterized ABC-type
                     nickel/dipeptide/oligopeptide-like import system contains
                     the type 2 periplasmic binding fold; Region:
                     PBP2_NikA_DppA_OppA_like_2; cd08498"
                     /db_xref="CDD:173863"
     gene            1558248..1559225
                     /locus_tag="Smed_5038"
                     /db_xref="GeneID:5319087"
     CDS             1558248..1559225
                     /locus_tag="Smed_5038"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21038 putative oligopeptidemurein peptide ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport system inner
                     membrane protein"
                     /protein_id="YP_001313751.1"
                     /db_xref="GI:150377155"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319087"
                     /translation="MPLISVVLGRLSQAFLLLIAMSLIGFIGVHSVGNPVFNVVNIET
                     ATPEDIRQATIALGLDQPIWRQYLLFINNVVRGNFGTSYIYHLPAFALVMSKLPATLE
                     LACVAMLIAAPVGTGLGLLAGRRSGTIFDRTVLRSSVFALSIPSFWLSMMLILLGAIL
                     TGWFPSGGRGTTARFLGQEWSFLTGNGLWHMVLPALALAIPNVALIARLSRSGTIEVE
                     NLDFTRFCRAKGLSSRRILLRHTLPNISVPIVTIIGLQFGGMLAFAVVVETIFSWPGV
                     GKLLIDSIQLLDRPVVMATLTFIAVAFVALNALVDLFYAVLDPRVRLSS"
     misc_feature    1558254..1559219
                     /locus_tag="Smed_5038"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppB; COG0601"
                     /db_xref="CDD:223674"
     misc_feature    1558536..1559159
                     /locus_tag="Smed_5038"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1558584..1558589,1558596..1558601,1558614..1558616,
                     1558647..1558658,1558662..1558691,1558698..1558703,
                     1558707..1558709,1558848..1558853,1558857..1558859,
                     1558863..1558865,1558872..1558877,1558881..1558883,
                     1558893..1558898,1558905..1558907,1558956..1558958,
                     1558998..1559003,1559010..1559012,1559031..1559042,
                     1559049..1559054,1559079..1559084,1559112..1559117,
                     1559124..1559129,1559133..1559138,1559145..1559150,
                     1559157..1559159)
                     /locus_tag="Smed_5038"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1558665..1558709,1559031..1559048)
                     /locus_tag="Smed_5038"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1558707..1558709,1558833..1558835,1559049..1559051,
                     1559073..1559075,1559082..1559084,1559112..1559114)
                     /locus_tag="Smed_5038"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1558908..1558946,1558962..1558967,1558977..1558979)
                     /locus_tag="Smed_5038"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1559239..1560114
                     /locus_tag="Smed_5039"
                     /db_xref="GeneID:5319088"
     CDS             1559239..1560114
                     /locus_tag="Smed_5039"
                     /note="PFAM: binding-protein-dependent transport systems
                     inner membrane component;
                     KEGG: sme:SMb21039 putative oligopeptidemurein peptide ABC
                     transporter permease protein"
                     /codon_start=1
                     /transl_table=11
                     /product="binding-protein-dependent transport systems
                     inner membrane component"
                     /protein_id="YP_001313752.1"
                     /db_xref="GI:150377156"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="GeneID:5319088"
                     /translation="MKAQIVSALKRRRHGPVLTASKLLLASYILVAIAAPLIAPQNPY
                     DPLQIYGWEASSPPGTRGSGGYLYLLGTDGLGRDIVSTILYGLRISLVVSIVSSALAA
                     LIGLTAGVSAAYFGKWVDIAIMRLVDLQLSLPTILIALIAIVTLGPGIDRIILALIIA
                     QWATYARIARGVALSEANKPYMDAARLMRLPTSRIIFRHLLPNSIAPAVTLIPIEVGH
                     AVALEATLSFLGLGVPIDKPSLGSAVANGFQYLLTGQYWISLFPGLALFGLIASINLV
                     GEDVRRSLDPRNHPL"
     sig_peptide     1559239..1559343
                     /locus_tag="Smed_5039"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.801) with cleavage site probability 0.797 at
                     residue 35"
     misc_feature    1559365..1560099
                     /locus_tag="Smed_5039"
                     /note="ABC-type dipeptide/oligopeptide/nickel transport
                     systems, permease components [Amino acid transport and
                     metabolism / Inorganic ion transport and metabolism];
                     Region: DppC; COG1173"
                     /db_xref="CDD:224094"
     misc_feature    1559551..1560045
                     /locus_tag="Smed_5039"
                     /note="Transmembrane subunit (TM) found in Periplasmic
                     Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters which generally bind type 2 PBPs. These types
                     of transporters consist of a PBP, two TMs, and two
                     cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2;
                     cd06261"
                     /db_xref="CDD:119394"
     misc_feature    order(1559557..1559562,1559575..1559577,1559605..1559616,
                     1559620..1559649,1559656..1559661,1559665..1559667,
                     1559716..1559721,1559725..1559727,1559731..1559733,
                     1559740..1559745,1559749..1559751,1559761..1559766,
                     1559773..1559775,1559824..1559826,1559866..1559871,
                     1559878..1559880,1559899..1559910,1559917..1559922,
                     1559962..1559967,1559995..1560000,1560007..1560012,
                     1560016..1560021,1560028..1560033,1560040..1560045)
                     /locus_tag="Smed_5039"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1559623..1559667,1559899..1559916)
                     /locus_tag="Smed_5039"
                     /note="conserved gate region; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1559665..1559667,1559701..1559703,1559917..1559919,
                     1559956..1559958,1559965..1559967,1559995..1559997)
                     /locus_tag="Smed_5039"
                     /note="putative PBP binding loops; other site"
                     /db_xref="CDD:119394"
     misc_feature    order(1559776..1559814,1559830..1559835,1559845..1559847)
                     /locus_tag="Smed_5039"
                     /note="ABC-ATPase subunit interface; other site"
                     /db_xref="CDD:119394"
     gene            1560111..1561784
                     /locus_tag="Smed_5040"
                     /db_xref="GeneID:5319089"
     CDS             1560111..1561784
                     /locus_tag="Smed_5040"
                     /note="PFAM: ABC transporter related;
                     Oligopeptide/dipeptide ABC transporter domain protein;
                     SMART: AAA ATPase;
                     KEGG: sme:SMb21040 putative oligopeptidemurein peptide ABC
                     transporter ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter-like protein"
                     /protein_id="YP_001313753.1"
                     /db_xref="GI:150377157"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR013563"
                     /db_xref="GeneID:5319089"
                     /translation="MTVEHVTTPLLRVQNLGLRHVSGSATTPILSDVSFELGRGEILG
                     IIGESGAGKSTVGNAILGLLSPEFQQTSGTIEFDGKAIDGMTADERQTLRGRRISAIF
                     QDHTASLDPLMSVGAQVEETCLTLDSSLSKREARARAIDLLARVGIPEPERRYRNYPH
                     QFSGGQRQRVVIAIALAGSPDIIIADEPTSALDATVQKQVLELLKILVDETGVSIILV
                     THDMGVISEITNRVLVMRKGQVVEADRTATILDQPRHDYTKKLLAAVPRLRIPTRTVK
                     AEDDGGQAGSSAIDGDQNPLLVAEGLSKQFAPQGFAWGIGRGKPRFGLRDVGIRLPRG
                     SITGIVGESGSGKTTFGRILAGLDTAPTGRITIGEHAFNVSRSGRRSGLLGRVQMIFQ
                     DPSVSLNPRMTIGETLDESIRFGGRTGSSKEPADLAAMMDRLGLPRSLLARHPHQLSG
                     GQKQRVCIARALLARPEIIVADEPTSALDVSVQAEIVGLLKDTIAERAMTMVFISHDL
                     AIVQAMCSSVFIFKDGRIEDFGPTEFIFSRSDNPYTRALINARPQRFTC"
     misc_feature    1560129..1561769
                     /locus_tag="Smed_5040"
                     /note="ATPase components of various ABC-type transport
                     systems, contain duplicated ATPase [General function
                     prediction only]; Region: COG1123"
                     /db_xref="CDD:224048"
     misc_feature    1560138..1560836
                     /locus_tag="Smed_5040"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    1560249..1560272
                     /locus_tag="Smed_5040"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    order(1560258..1560263,1560267..1560275,1560417..1560419,
                     1560666..1560671,1560768..1560770)
                     /locus_tag="Smed_5040"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    1560408..1560419
                     /locus_tag="Smed_5040"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    1560594..1560623
                     /locus_tag="Smed_5040"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    1560654..1560671
                     /locus_tag="Smed_5040"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    1560678..1560689
                     /locus_tag="Smed_5040"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    1560756..1560776
                     /locus_tag="Smed_5040"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     misc_feature    1560831..>1560950
                     /locus_tag="Smed_5040"
                     /note="Oligopeptide/dipeptide transporter, C-terminal
                     region; Region: oligo_HPY; cl07097"
                     /db_xref="CDD:244611"
     misc_feature    1560996..1561700
                     /locus_tag="Smed_5040"
                     /note="ATP-binding cassette domain of nickel/oligopeptides
                     specific transporters; Region: ABC_NikE_OppD_transporters;
                     cd03257"
                     /db_xref="CDD:213224"
     misc_feature    1561131..1561154
                     /locus_tag="Smed_5040"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    order(1561140..1561145,1561149..1561157,1561284..1561286,
                     1561524..1561529,1561626..1561628)
                     /locus_tag="Smed_5040"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213224"
     misc_feature    1561275..1561286
                     /locus_tag="Smed_5040"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213224"
     misc_feature    1561452..1561481
                     /locus_tag="Smed_5040"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213224"
     misc_feature    1561512..1561529
                     /locus_tag="Smed_5040"
                     /note="Walker B; other site"
                     /db_xref="CDD:213224"
     misc_feature    1561536..1561547
                     /locus_tag="Smed_5040"
                     /note="D-loop; other site"
                     /db_xref="CDD:213224"
     misc_feature    1561614..1561634
                     /locus_tag="Smed_5040"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213224"
     gene            1561872..1563110
                     /locus_tag="Smed_5041"
                     /db_xref="GeneID:5319090"
     CDS             1561872..1563110
                     /locus_tag="Smed_5041"
                     /note="possibly related to processing of cell wall amino
                     acids; KEGG: sme:SMb21041 conserved putative protein,
                     possibly related to processing of cell wall amino acids"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313754.1"
                     /db_xref="GI:150377158"
                     /db_xref="GeneID:5319090"
                     /translation="MNDRFTLAVTGQSLIKHDIRDIPAPAFREVQSLLRQADLSFTNF
                     EGTILGTHGGWPLKGSFFGCSDPAVLDALGAIGFQALSLSNNHAFDLGPSGVLSTLEE
                     VEKRGFFHAGLGRNAREVSRASIATINQRRIALVAMDGGPGPDFMYAADADENRPERP
                     GVNRLRLSQLLEVDDLAFEQIRAVRDKIGYTAIDLANDSQPDDPPRLDPQAEVAIARS
                     VFKRSDRYGRGVRIDEVDMARNLAAIASAARDSALVIAYLHHHHWASDWYQLPEWVSG
                     VAKRCIDAGASMFVSHGAPVLQPVEIYRGRPIFYSLGNFIFHVQSEKSTWTAAEVWES
                     VVGVCSFASDNSLINISFHPVVIGGEHGLEDGVLERRLVPQLVTGDSAVRILGRLQEQ
                     SARLGAHIEISGNVGRLQAR"
     misc_feature    1561890..>1562432
                     /locus_tag="Smed_5041"
                     /note="CapA and related proteins, metallophosphatase
                     domain; Region: MPP_CapA; cd07381"
                     /db_xref="CDD:163624"
     misc_feature    1561896..1563062
                     /locus_tag="Smed_5041"
                     /note="Putative enzyme of poly-gamma-glutamate
                     biosynthesis (capsule formation) [Cell envelope
                     biogenesis, outer membrane]; Region: PgsA; COG2843"
                     /db_xref="CDD:225399"
     misc_feature    order(1561905..1561907,1561911..1561913,1562004..1562006,
                     1562127..1562132)
                     /locus_tag="Smed_5041"
                     /note="putative active site [active]"
                     /db_xref="CDD:163624"
     misc_feature    order(1561905..1561907,1561911..1561913,1562004..1562006,
                     1562127..1562129)
                     /locus_tag="Smed_5041"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:163624"
     misc_feature    <1562631..1562825
                     /locus_tag="Smed_5041"
                     /note="Bacterial capsule synthesis protein PGA_cap;
                     Region: PGA_cap; pfam09587"
                     /db_xref="CDD:220300"
     gene            1563228..1564472
                     /locus_tag="Smed_5042"
                     /db_xref="GeneID:5319091"
     CDS             1563228..1564472
                     /locus_tag="Smed_5042"
                     /EC_number="3.4.11.4"
                     /note="catalyzes the release of the N-terminal amino acid
                     from a tripeptide"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="YP_001313755.1"
                     /db_xref="GI:150377159"
                     /db_xref="InterPro:IPR001261"
                     /db_xref="InterPro:IPR002933"
                     /db_xref="InterPro:IPR008007"
                     /db_xref="InterPro:IPR010161"
                     /db_xref="InterPro:IPR011650"
                     /db_xref="GeneID:5319091"
                     /translation="MRTRDELVSRFFRYVAIESQSNGHSASLPSSPGQFELASLLAEE
                     LRMLGIEDVVLDQQAIVTGVKRGTRPNAPRIGFIAHLDTVDVGLSAIIRPQILRFEGT
                     DLCLNPQEDIWLRVAEHPELLAWSGEDIIVSDGTSVLGADNKAAIAVIMTLLARLDAQ
                     GAHGDVFVAFVPDEEIGLRGAKALDLARFACDFAYTIDCCELGEVVLETFNAASAEII
                     FTGVSAHPMAAKGTLVNPLLMALDFVSHFDRKDTPECTQDRQGFFWFKELVAHDSKAT
                     LNVLVRDFDAAEFERRKQQLLAITALVNAHYPSGRVECRLTDTYHNIGRRLRDDSRPG
                     TLLFQAFDALGIEQKRIPMRGGTDGAVLSARGIPTPNFFTGAYNFHSRFEFLPVSAFE
                     KSFEVAAMLCKLAAQDEALADR"
     misc_feature    1563228..1564445
                     /locus_tag="Smed_5042"
                     /note="Di- and tripeptidases [Amino acid transport and
                     metabolism]; Region: PepD; COG2195"
                     /db_xref="CDD:225106"
     misc_feature    1563246..1564439
                     /locus_tag="Smed_5042"
                     /note="M20 Peptidase T specifically cleaves tripeptides;
                     Region: M20_peptT; cd03892"
                     /db_xref="CDD:193512"
     misc_feature    order(1563465..1563467,1563651..1563653,1563747..1563752,
                     1563819..1563821,1564365..1564367)
                     /locus_tag="Smed_5042"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:193512"
     misc_feature    order(1563483..1563485,1563900..1563908,1563912..1563920,
                     1563924..1563926,1563930..1563932,1563936..1563941,
                     1563948..1563950,1563957..1563959,1563984..1563998,
                     1564011..1564013,1564017..1564043,1564287..1564289,
                     1564365..1564367)
                     /locus_tag="Smed_5042"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:193512"
     gene            complement(1564658..1564957)
                     /locus_tag="Smed_5043"
                     /db_xref="GeneID:5319092"
     CDS             complement(1564658..1564957)
                     /locus_tag="Smed_5043"
                     /note="PFAM: protein of unknown function DUF736;
                     KEGG: nwi:Nwi_0840 protein of unknown function DUF736"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313756.1"
                     /db_xref="GI:150377160"
                     /db_xref="InterPro:IPR007948"
                     /db_xref="GeneID:5319092"
                     /translation="MAQIGTFTRDETGAYAGTIKTLTLNVKATIRPCDRGNDRAPDFR
                     VTAGGVEFGAGWTRTARETGAEYLSLKLDDPSFTAPVYASLVQGDKGEHKLIWSR"
     misc_feature    complement(1564661..1564954)
                     /locus_tag="Smed_5043"
                     /note="Protein of unknown function (DUF736); Region:
                     DUF736; pfam05284"
                     /db_xref="CDD:218537"
     gene            complement(1565986..1566342)
                     /locus_tag="Smed_5044"
                     /pseudo
                     /db_xref="GeneID:5319093"
     gene            complement(1566541..1566789)
                     /locus_tag="Smed_5045"
                     /db_xref="GeneID:5317919"
     CDS             complement(1566541..1566789)
                     /locus_tag="Smed_5045"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313757.1"
                     /db_xref="GI:150377161"
                     /db_xref="GeneID:5317919"
                     /translation="MLLSWKIGNRQVARYRWKGFGTSDLFDTPDFPGTNKQIEENRVI
                     KRKRRHRRSADVRINWLQPHADGQALACSAELCGPDNS"
     gene            1567167..1567466
                     /locus_tag="Smed_5046"
                     /db_xref="GeneID:5317920"
     CDS             1567167..1567466
                     /locus_tag="Smed_5046"
                     /note="PFAM: protein of unknown function DUF736;
                     KEGG: nwi:Nwi_0840 protein of unknown function DUF736"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313758.1"
                     /db_xref="GI:150377162"
                     /db_xref="InterPro:IPR007948"
                     /db_xref="GeneID:5317920"
                     /translation="MAQIGTFTRDETGAYAGTIKTLTLNVKATIRPCDRGNDRAPDFR
                     VTAGGVEFGAGWTRTARETGAEYLSLKLDDPSFTAPVYASLVQGDKGEHKLIWSR"
     misc_feature    1567170..1567463
                     /locus_tag="Smed_5046"
                     /note="Protein of unknown function (DUF736); Region:
                     DUF736; pfam05284"
                     /db_xref="CDD:218537"
     gene            1567604..1568056
                     /locus_tag="Smed_5047"
                     /db_xref="GeneID:5317921"
     CDS             1567604..1568056
                     /locus_tag="Smed_5047"
                     /note="KEGG: rle:pRL80113 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313759.1"
                     /db_xref="GI:150377163"
                     /db_xref="GeneID:5317921"
                     /translation="MFCGNPLEVELGAAWQKRSSESDRDYLSVKLDAPSFPAPIYATL
                     AEVDGRRSMTPPSRDARHGRRRQQEKRWKIEGLCTESYRSAASGLVCHEAAMYVITDD
                     DLHLGVFPVRSSGPGGLIRLFDGVLPQSHDERKKQKPDLEALTLIPPQ"
     misc_feature    <1567628..1567777
                     /locus_tag="Smed_5047"
                     /note="Protein of unknown function (DUF736); Region:
                     DUF736; pfam05284"
                     /db_xref="CDD:218537"
     gene            complement(1568391..1569914)
                     /locus_tag="Smed_5048"
                     /db_xref="GeneID:5317922"
     CDS             complement(1568391..1569914)
                     /locus_tag="Smed_5048"
                     /note="PFAM: Integrase catalytic region;
                     KEGG: sme:SMc03283 putative transposase for insertion
                     sequence ISRM18"
                     /codon_start=1
                     /transl_table=11
                     /product="integrase catalytic region"
                     /protein_id="YP_001313760.1"
                     /db_xref="GI:150377164"
                     /db_xref="InterPro:IPR001584"
                     /db_xref="GeneID:5317922"
                     /translation="MRKVSMATRAELVAAISCRYVLGGRAEKARMLDEFVALTGFHRK
                     HAMRLLRGDREPAKGGPRPGRRVYGDDVRAALVGVWEASDRICGKRLHPLLPTLIEAM
                     ERHGHGDMNCETRRQLLAMSPATIDRVLKEIKASATGPRRRKGSTAIRRSVPVRTFSD
                     WDDPAPGFVEADLVSHSGPYARGAFSQTLVLTDIATGWTECAPLLVREQTVLITALAE
                     LRKLLPFPLLGFDTDNDSVFMNESVHEYCLRDNIELTRCRPYRKNDQAFVEQKNGAIV
                     RKIVGYRRFEGLRATRELAKLYSSMRLFVNFFQPSFKLKEKHRDGAKVVKRYHRPATP
                     YQRLLDDPRTPEDTCLRLKAMYLTLDPVRLLRDIRLAQTRLVEIADKPDGSPATDGEA
                     LPLEDFLSGLRIAWRGGEVKPTARSKPAAKRERRRPDPLLAVTAELEEWFEAEPWRTS
                     RELLERLQVKYPGVYPDRLIRTVQRRMKIWRSTQANALVFGPFADVARQTQIVEVVQ"
     misc_feature    complement(1569078..1569350)
                     /locus_tag="Smed_5048"
                     /note="Integrase core domain; Region: rve; pfam00665"
                     /db_xref="CDD:216050"
     gene            1570053..1570421
                     /locus_tag="Smed_5049"
                     /db_xref="GeneID:5317923"
     CDS             1570053..1570421
                     /locus_tag="Smed_5049"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001313761.1"
                     /db_xref="GI:150377165"
                     /db_xref="GeneID:5317923"
                     /translation="MSCSGSTRAAPYAPLQELSTSHSFLIRSRRNLLQVNIEDAVVAG
                     QELRLFQRGNKRHIDNAVIRYPPSAVLNGQFHDADCDRAVRSRCHPTLGVAAFDPGRQ
                     RLSMKVVKLEPPDYTSSASL"
     gene            complement(1570397..1570591)
                     /locus_tag="Smed_5050"
                     /db_xref="GeneID:5317924"
     CDS             complement(1570397..1570591)
                     /locus_tag="Smed_5050"
                     /note="PFAM: Conjugal transfer TraD family protein;
                     KEGG: rle:pRL70084 putative conjugal transfer protein"
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer TraD family protein"
                     /protein_id="YP_001313762.1"
                     /db_xref="GI:150377166"
                     /db_xref="InterPro:IPR009444"
                     /db_xref="GeneID:5317924"
                     /translation="MARAMTSDARKKDTREKIALGGLIVKAGLRYEKRALLLGALVEL
                     SRRLKSDEGEASSQSDAEDV"
     misc_feature    complement(<1570424..1570591)
                     /locus_tag="Smed_5050"
                     /note="conjugal transfer protein TraD; Provisional;
                     Region: PRK13847"
                     /db_xref="CDD:172372"
     gene            complement(1570596..1570892)
                     /locus_tag="Smed_5051"
                     /db_xref="GeneID:5317925"
     CDS             complement(1570596..1570892)
                     /locus_tag="Smed_5051"
                     /note="PFAM: TraC family protein;
                     KEGG: ret:RHE_PA00158 conjugal transfer protein C"
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraC"
                     /protein_id="YP_001313763.1"
                     /db_xref="GI:150377167"
                     /db_xref="InterPro:IPR012930"
                     /db_xref="GeneID:5317925"
                     /translation="MKKPSSKIREEIGKLQEQLKQAETREAERIGRIALKAGLGEIEI
                     DETELQDAFEHLARRFRGELAASIGGRKRVEDGIPSTATATVASGAAQGGHGEV"
     misc_feature    complement(1570653..1570892)
                     /locus_tag="Smed_5051"
                     /note="conjugal transfer protein TraC; Provisional;
                     Region: PRK13848"
                     /db_xref="CDD:172373"
ORIGIN      
        1 gggcgcaagg cactactgta aatccgacaa tcgccaactg cgatggtttg gtggatcatc
       61 ccggccgttc cgaaggagcg gtatccaagg gcgcaattat acgtcgccag ggcgacgttc
      121 ttgctctcag ccgtggcggc gccgccgctc tcgacgaacc cgttgaactc gttggcaatc
      181 gggagctcag agcgacgtgg ccgttcctca cttctccgtc agcctcatca cccgtggctc
      241 cggccgcagc gcagtgctgt ctgcggcata tcggcattgc gcgaagatgg cgtaccaacg
      301 ggaagcccga acgattgact acacccgcaa gactggactt cttcacgagg agttcgtcat
      361 cccggacaac gcaccggaat ggttgcagtc gatgatcacc gatcgctcgg tctccgacgc
      421 agcggaagca ttctggaaca aggccgagga tttcgagaag cgctccgacg cccagcttgc
      481 caaggaggtc acaatcgcgc tgccgatcga gctgacgtct gcacaaaaca ttgctctcgt
      541 ccgtgacttc gtggagcagc acatcagcgc caagggaatg gtggcggact gggtttatca
      601 cgacgcgccg ggcaatccgc atgtccactt gatgacgacg ctgcggcccc tgacgcaaca
      661 gggtttcggc gccaagaagg tcgccgtcct tgggccggac ggctatccaa tccgcaatga
      721 cgccggcaag attgtttacg agctttgggc cggaagtctc gacgacttca acgccttgcg
      781 cgacggttgg ttcgcctgcc aaaaccgcca tctgacgctt gccggcctcg acctccgcat
      841 cgatggccgt tctttcgaga agcagggtat cgagctcgct ccgaccctcc acctcggcgc
      901 cggcacgaag gcgatcgagc ggaaagcgac ggcagaggcg aagacgcttt cgctcgagcg
      961 cctgcagcta caggaggacc tgcggagcga gaatgcccgg cgccttcagc gtcgaccgga
     1021 gatcgtgctc gacctgatca cgcgagaaag gagcgtgttc gatgaacgcg acgtggcaaa
     1081 gatcctgcat cgctatgttg acgatcccgc ggttttccgg agcctgatgg cgcgcatcct
     1141 gcagagcccc gagacactcc aactcgaacg cgaacgaacc gcttttgcca ccggcatccg
     1201 ggctccggca aaatacacga cgcgcgcgct gatccggctc gaagcggaga tggcaaaccg
     1261 tgcgatctgg ctctcaaggc aatcctcgca tcggcttcgg gaagcggtgc tggaggcgac
     1321 gttggcgcgc cattcgcgcc tgtcggacga acagaaaacg gcgatcgagc atgttgcgaa
     1381 agccggccgg atcgccgctg taatcggtcg tgccggtgcg ggcaagacga ccatgatgaa
     1441 agcggcgcgg gaggcgtggg aagcggccgg ctaccgggtg gtcggcggcg cgcttgcagg
     1501 caaggcggcg gagggtctgg agaaggaagc gggcatcatc tcccgcacgc tgtcggcgtg
     1561 ggagctgcgt tggagccaag gtcgcaacca gcttgacgcc aggacggtct tcattctcga
     1621 cgaggcgggc atggtctcgt ccagacagat ggcatgcttc atggaggccg cgacgaggac
     1681 gggggcaaaa ctcgtccttg ttggcgatcc ggaacagctt cagccgatcg aagcgggcgc
     1741 ggcgttccgc gcaatcgccg atcgcatcgg ctatgccgag ctcgaaacca tctatcgtca
     1801 gcgtgaacag tggatgcgcg atgcgtccct cgatctcgcc cggggcaatg tcggcaaggc
     1861 tgttgaggct taccgtgcca acggcaggat gatcggagcc gagctaaagg ctgaagctgt
     1921 gcggaacctt atcgtcgact ggaaccggga ctacgatccg acgaagacca ctttgatcct
     1981 cgctcatctt cgccgcgacg tacgcatgct caatgagatg gcccggtcca aactcgtcga
     2041 gcgtggcatc gttggcgaag gctttgcttt ccgaaccgcg gatggaaacc gcaactttgc
     2101 ggccggtgac cagatcgttt tccttaagaa cgaaggctcg ctcggcgtca aaaacggcat
     2161 gctcggaaag atcgtcgaag cttcgccgaa ccgcgttgtc gcggaaatcg gtgcgggcga
     2221 gcaccaccgc caggtgatca tcgaacagcg cttctacaac aatcttgacc acggctatgc
     2281 caccacaatt cacaagagcc agggcgcaac ggtggaccgg gtgaaggtgc tcgcttcgct
     2341 ttccctcgac aggcatctgg tctatgtcgc catgacccgt caccgcgaca atctcgacgt
     2401 ctattacggc gcccgatcct ttgccagggc cggcggactg atccaggttc tgtcacggaa
     2461 gaattcgaag gaaaccacgc tcgattacga gaaggccacc ttttatcggc aggcgctacg
     2521 cttcgccgaa gcccgcggcc tgcacctcct caatgtcgcc cgtacgatcg ctcgcgaccg
     2581 gctcgcctgg acggcccggc agagctccag gcttgccgat ctggctcacc gtctcgttcg
     2641 gatcggccgc aagctcgggc tcgccgccgg caccaatcca atcaactcgc aaaacagcaa
     2701 ggagaccagg cccatggttg ccggtatcgc gacacatccg gaatcggtgg agcaagcagt
     2761 cgccgacaag ctcgcagcag accccggctt gaagaagcag tgggacgatg tgtcgacccg
     2821 cttccatctg gtctatgcgc atccggcagc ggcgttcaag gcggtgaaca tcgacgtcat
     2881 gctgaaggac gagaccgccg ccaaagcgac gctctctaaa atcgccaagc agccggacag
     2941 ctacggtgca cttaaaggca agactggttt gctcgccagc cgcgccgaca ggcaggaccg
     3001 cgagagggcg gtacgcaacg ttccggctct ggtccagagc ctcgatggtt atatgcgtca
     3061 gcgcggcagc gccgaacgac gctaccgggc cgaggaattg gaagcccgcc gcaaggtagc
     3121 gatcgacatc ccggcgctat ctccaggcgc ccggcaaata ctggagcgcg tgcgtgatgc
     3181 cattgaccgc aacgatcttt ccgctgcgct cgagttcgca cgcgccgacc ggcatgtgaa
     3241 agctgaactc gacggattcg caaatgcggt cgacgcgcgc ttcggcaaac gcaccttcct
     3301 tccactgagc gccagggaca caaacggaga caccttcacg tcggtcacgg caggcatgca
     3361 tccgggccag aggctggaag tcgaatcggc atggaaagca atgcgcacgg tgcagcaact
     3421 cagtgcccat gagcgcacga ctgaggcctt gaagctttca gaaacattgc gcctgagcaa
     3481 gagccagggg ctctcgctga gatgagcatt ccactccttc aaacagcgcc gacgagacga
     3541 cgccgtacgc cattcctcct tggcttggcg atggcccctt tactttttct tggtgcaatc
     3601 tagagcgagg aacagcttga cagtatgagt tctgtccgga aatttccttg agcgctattc
     3661 gatatcaaat cgctcaagca tcttcgtgag ccaaaggttc tgtgcaccga gctgtttagc
     3721 cagcaaactc ctgggcgctt gttgtctgcg tccagggcgg caagctcgtc gggagatcgg
     3781 atcgtcggca gtctgcgcct ttcgatcctc atgcccgacc tgcgagttca acgcgatcgg
     3841 ctgagcggga gctcgcttga cgcgccttcg cggagcaact tcaccattgc aggtcgggga
     3901 accgctccaa aggcgcgcta tagacgtagt tacgccagag attcaagtga atcagatctg
     3961 ttcaatgtat gcgactgcgc ttgccaccgc gctggcaacc cactttccga agtagttcag
     4021 caggaaggtt cagttgattc agttgctcga ctctcgaggg gaccgcattt aacgtcttcg
     4081 gctaagatca gcacgtcgcc cataaggaca ggcggaacat atgaccgact ccctcgacca
     4141 cgcacaagcg aacaatatgc cacaatttct ggggctgacc gtcggagcaa tcggcgtagt
     4201 ttatggcgac atcgggacca gttccctcta tgcctttcgc gaggcgctgc gcacgtttgg
     4261 accaggtggt gtcgggcggg acgaagtcat cggtctcgtc tcgctggtac tctgcacgct
     4321 gaccgccatc gcaactttga aatacgtcat cttcctcctt cgcgccgaca acgacggcga
     4381 gggtggaacg ttgtccttgc tcgccctgct gctgaagaag ggcacaaaga atccagtctt
     4441 gatgtttttt gccggcattc tcgtattttt tctaatgttc agcctgacga aagagacgac
     4501 atgaatcttt ccgtgcgcct ggcactcctc ggccttgcct gggtgatggt cggcttggca
     4561 actgccggaa tatttctccc gctgctgccg acgacaccat ttctcctgct ggcggcatgg
     4621 ttgttttcgc gctcttcgcc gcgcctcgag caatggctgg caggacacgc cctgtttggg
     4681 cccccattgc gagactggcg ggatgacggc gctattgcgc ggcgcaacaa aatctgcgcg
     4741 atcttactga tggctctggg ttttgcctat ttctggctgg cgatcgagcc gccggccatc
     4801 ggcttgcttg cggtcgcagc gatcatgatc gcctgcggca tcttcatcgc cacgcggccg
     4861 gaaccgccga ataaatgatg atcagagtgc ttaccccttc gtcaggcgat caccttcatg
     4921 attataggtc aagggaccta taatcatgaa ggtgatcgaa tccaaaaggt gacagcggga
     4981 tacgggcggg aaaccggggt acacttttcc tcaaacttgc tctaatggtt cggcacgatg
     5041 tccattttca cggcgctcag atctggcgga tcgccaacct cgtctgcgac caggatcgac
     5101 atggcgagga tgaagacggc tacaccgagt cccgctaaca tttcggcgtc catcgctgac
     5161 tcccttgtgc tccgggtgag taaaggccac ggaacctcgc ctggagcaac cctcaatttt
     5221 taggaacttc cgggaaaagc gtcggcgatc ttcgatccgg gagcacgtcg aaacgaagag
     5281 taagatcatt tctctgtttt gcggtggagg agagaaatga tcttacgtgc agcctcgcgt
     5341 ggcgcgcccg gctcagccgg ctcggaccgt ggccctgcct tcctccacca gccgtgtcgc
     5401 cgcgtctccg atcgatatcc gctcgaaggc gagttcatcg gcaatcggcc gcagcacgcg
     5461 ctggtcgaac tcggtcgctc caagcggcgc cggcgacgga tagctcccca cctgatcctt
     5521 gaggccgttg atatatttca ccgtttccgt ttcggtcggg ttgagtgacg gcaggatggc
     5581 ttcgcgaacg gtcggcgaca tgggcacgcc gcgctccacg ccgaggatct tgccggcctc
     5641 cacgtcattg acgaagaagt tgatgaattt cgcggcctct tcgccgtgct ccgtcgacgc
     5701 accgatgctc cagatcagcg ccggccggta gtaatggccg gagggacctc ctttctcggc
     5761 acggggcagc atgccgatgc caagcttgct tttcatgatg agctgatagc cgaccatctg
     5821 gttggaatag gccatgccca tcgccgaata gccgagcgcc aggcagttgg tgtcgatcgt
     5881 gttctggtcg agcgtctgga tgtccgctcc gacggtgccg ccgcgcttgc gcaactcttc
     5941 ccaataggca taccattcct tcgcctcctc gaccccgaaa ccgaggccgc tatcggtata
     6001 gaggctgctt cctcgctgac ggagccaggc atcgaacaca taggcgtagc gggctccgta
     6061 gggaccgccc ccggcacttt tcttcccgac cgccttggtc atttcgacgg cgatctcagc
     6121 atattccgcc caggtggtgt caattcccgg cggatcgatg cccgctctgg caaaagcgtc
     6181 ggcatcgtag aacagcgcga aagaattgag gccaagcccc acaccccaga gctttccatc
     6241 caccgtcgtc agcttcagga cgtccttgcc gaatgcgtcg acgtccaacg ccgaagagat
     6301 gaaggggtcg agcgccatgc aggcgcccct cttggagtaa tccgagatcg tgctgggctc
     6361 gagctggaag atatcggcaa tggaccgacc ggccatctgg gtcgcaagct tcgtccagta
     6421 gccgtcgccg ctcaagcttt cgccgatgat cctgatatcc gggttggctt ccgcgaaaag
     6481 cttggcgact gccaatgttc gcttcgagcg gtcgttggat ccccaccaca tggcgcgcaa
     6541 ctgcacgctt tcggccgcga gggtcgttcg ggacccgaga gcgacacctg ccgcggcacc
     6601 agccgcgccg gccatgaatc cgcgtctgtt gagtagcatg ccaatcctcc cctttgctgc
     6661 cctgcccggc actctcctca gcacctgcag gctccaagtt gcgcaagagc ttatgcaaaa
     6721 ttataattta cgcaatattt ctttttaact tgcaaatttg cattggttgc gcaatgtttg
     6781 caccatgatc gaaagaccct cgagaagact ccgccaagcc gacatcgccg cccatgccgg
     6841 cgtatcggtt tctaccgtct cgcgcgtgct cgccaacgaa cccggcatca gcgaagatgt
     6901 ccgggtacag atcttcaagg tcgcaagcga gctcggctac ccactcaaag ccggcactgc
     6961 agctggttca cgcgcactgg cattgatcgc aagcaacggc gttaccggcg gcttgagcgc
     7021 tttttaccag ggcatcgtcg atggcttgcg ctcagaggca gccgcgcagg gcatgtcgtt
     7081 cgacatccgc ctcatcaacg agatgaaggc gacgccgcaa gtcgttggcg aacatctgga
     7141 atcagtcggg gcgcaagggc tctttctggt cgggatcgac cccagcgagg cacttggcga
     7201 ctggctcgtg gaaagccggt tgcccgtcgt cctcgtcaat ggcgtcgatc cacaattgcg
     7261 cttcgacggc atctcgccgc caaacttctt cggcgccttc gctgccacgc ggatgctgct
     7321 ggatgccggg cacaggcgca tcctccacct gaccggatcg catcgccata cgatccgcga
     7381 gcgtgtgcgc ggcttcgaag cggccatcgc ctgcgctgaa ggctgcgcgg cgcgcatcgt
     7441 ccgcctgccc ttcgagacca attcgagcgc ggaagcccat gcggcaacgc tcgatgcgct
     7501 cgccgtggac gggaatttca ccgcggcctt ctgcatgaac gatttcatcg cagtgggcgt
     7561 tctcgaggcg gtcaccgaac ttggccgccg cgtaccggat gatttcgcca ttatcgggtt
     7621 cgacgacctg ccctgcgccg agatggccaa tccgcgcctt tcgacgatgc atgtcgaccg
     7681 tgcagcgctc ggccgggaag cggtcggcat gatgcagttt cgcttcgctc atccggacgt
     7741 gcccgcgcgg catgtctctc acgcggtcac cccggtgccc ggcggcacga ttgcacgaag
     7801 gacgacgcat gacctatgat cccgccagcg ccaatccgct tgccggaaat ccgctccaaa
     7861 agcgcggcga catgcagagc gcgcttctcg atctgttcga tccgctcctc ccctatttct
     7921 ccaccggcaa tgcgcgggtc cgtctcgacg ccgctgctgc gcatttcgac cgggccgctg
     7981 ccgatctgga aggctttgca aggcctcttt ggggccttgc accttttgct gccggtggcg
     8041 gagacttcgg gcattgggac cgctatgcgg aagggatcgc caatggcacg gatcctcaac
     8101 atccggagtt ctggggccag gtgaacggac gggatcagcg aatggtcgaa cttgcagcgc
     8161 tgggcttcgc cctggcgctg gtgccggaaa agctgtggga tcccttgagc cggcgcgcgc
     8221 gggagaatct cgtcgcctat ctcctccacg cccgcacctt cgactatgcc gacaacaact
     8281 ggaagttctt tcgtattttc gtcgacatcg ccctcgatcg cctcggcatc gatcatgacc
     8341 gcagcttgac cagatcctat ctggctgaac tggacggttt ctatattgcc gatggctggt
     8401 atcgcgacgg caatgtgcgg cgcgtcgacc actatatcgc cttcgccatg cacttttacg
     8461 ggctcatcta tgcgcgcctt gtagacgacg accatgcgaa gcgataccgc gaacgggcga
     8521 tctccttcgc gcaggatttc cgccactggt ttgccgagga cggggcaacg ctccctttcg
     8581 gacgaagtct cacctatcgc ttcgcctgcg ccggtttctg gtcggcactc gcctttgccg
     8641 acctcgaggc gctgccctgg ggggaaatca agggactgtg cctacgccac ctcagatggt
     8701 gggcggacaa gccgatagcg catagggacg gcgtgctctc tatcggttac ggctatccga
     8761 acctcctgat gtcggaaagt tacaattcgg cgggctcgcc ctattgggcg ttcaaggcct
     8821 tcctgccgct tgccacaggc gaaaaccatc ccttctggac gagcacggaa gcgccgctgc
     8881 agcaatccac cgagccattg gatctgcgcc atgcaggcat ggtcatgatg ccggtcaatg
     8941 gtgacgtcgt ggcgctttcc tccggccagg aaaaccgcca aatgcgcttc ggctcggaaa
     9001 aatacgcgaa attcgcgtat tccgcgcgct acgccttcag catcgagagc gacgaacggg
     9061 gattcgttgg cggagctttc gactcgatgc tggccttcag cgacgacggc atccactacc
     9121 gggtgcgcga ggccaatgag gaggtactga tcgcgggcga tgtcttgttc tccaaatggt
     9181 cgccatggcc cgatgttctg gtcgaaacct ggctgatccc ctcctctccc tggcatgtgc
     9241 gcgtgcacag gatcaccacc ccgcgaccgc tggaaacggc cgaaggcggt ttcgcgatcg
     9301 atagacgaga cttcgatgcc gacacgctct tcgcagcaga agggacggct cacgccatcg
     9361 gggccgagga tttcagcggg attcgcgatc tcggctcgac cgtcccgcgc gagggtatca
     9421 ttcagaaagc tccgccgaac accaatctga ttgccgcaag gacgcttgtg ccgcaattgc
     9481 ggacttcgat cccatccggt gagaccgtcc tgggatgcgc cgtgatcgcg ttccgcaaca
     9541 atcccgcgct cgccgaagcc tggcccagcc cgccggtgat gcccgacatc gaaaagctcg
     9601 tcgccatccg cgcggaaggc ctcaacgtca gcacgatgct ggcgccggga cggatcccat
     9661 gagccttccg accgtcgcct ttgcgatgca gcccgaaaga acgcgctatg tcctgacgcc
     9721 tgagcttctc aagcggctcg ccggcctcgc ccgcatcctc gatgaacggc cgatcaccga
     9781 attcgacgag cgggcgaagc gattgctagg cgaggccgag atcctggtga cgggatgggg
     9841 tgcaccgttc ttcgatgagg ccgccctcgc ccgggcgccg caccttcggc ttatcgtgca
     9901 tgccgccggc acgataaagg ggctcgtcgg ccgtagcgtt ttcgaagctg ggatcaaggt
     9961 aagccatgcg gccgaggcca atgccgttcc cgttgccgag ttcacgcttg cagccgtgat
    10021 cttcgccgga aaacgggtgt ttcagttccg cgacatctat gtggccgacc ggggccgcgg
    10081 gcgcatccag accctgcagg gggaagccat cgggaatcac cgccgcatcg tcggcatcgt
    10141 cggcgcttcg cggatcgggc gccgtgtgat cgagctctta cgtctcttcg actatcaatt
    10201 gctgctctac gatccgctga tcagcgaggc cgaggcggag gcactcgggg ccgagaaggt
    10261 cgatctagcg gcactgatgg cccgctccga catcgtgtcg ctgcatgcgc ccctgctgcc
    10321 tgagacccgg cacatgatcg atgcccgcca gctcgccctc atgaaggaag gagcgacgct
    10381 gatcaacact gcgcggggtg cgttggtcaa tgaagcagcg ctcatcgcaa agctgcagac
    10441 gggttcgatc aatgcagtga tcgacgtcac tcacccggaa attccggagg ggaactcacc
    10501 gctctacgat ctgcctaacg tctttctgac gccgcatatt gccggcgcca tcggcctgga
    10561 gcgcaggcgt ctcggggaaa tggctgtcga tgaggtcgcc cgcttcctgg aaggcaagca
    10621 gctgctcttc gaagtgctca agcaggacct ggcgaggatc gcatgatcgg tatcgagccc
    10681 gccctctgtt cggtgacctt ccggaagatg cccgcagacg agatcgttgc acttgccgtg
    10741 gaggcgcggc ttgcggccgt cgaatgggcg ggagatgccc atgtctctcc cggagatctg
    10801 cccgccgccc gcgccgtggc tcggcggtgc gaaaatgccg gcctcaagac gtcctacggc
    10861 tcatacatcg cgccaccgac cgacgacttt gccgcgttca agtcggcgct ggagacagcg
    10921 gtcgcacttg gtgcgtcgaa tatccgtatc tgggctggca cgcgcgagcg cgattccagc
    10981 aattacagcg ccgaggaacg acgccacgcc gcagaggcaa tccgccagat gggggcagaa
    11041 gctgcccggc atggggtcac ggtatcgctc gaatatcatc cgcagtcgct gaccgatgaa
    11101 accctttcgg cgcaaagcct tattgaggcg gtcgggcatc cgaatgtcta tctctactgg
    11161 caaccgcggc ccggtctccc gcttaaggag gcgcttacgg aaatcgctca ggtcggtgag
    11221 catatatcgc atgtccacgt gtttgcctgg gaccgctgtc gcaaccgctt cgccttggca
    11281 accgccgccg actactggcg aacggtcctt actgccttgc cccaatcgcg ctggagaggc
    11341 cggcgcttcg ccatgttgga attcgtggcg ggagacgatc cggcagcttt tctggcggat
    11401 gctggaacgc tcaggcaaat tttgagagtg gagctttcgc ttcggacatc cggcgatgca
    11461 gatggtgatt aactgcagcg cagccgttgc gattttgcca aacggcagaa ataagctata
    11521 gtttcgccag aaagcgaggt ccgatgcagc ttcagccaat tgtcacgaca ccaaccgcta
    11581 caacagatgc gataaccgac gcggaagccg gcgcgttggc acgtgctgtc gtaaacctct
    11641 ctagagcctg gaagctctcc gacgctgagt cgtgcattct cctaggaggg atgtcccccc
    11701 gcacctgggc gcggtggaag gacggtgaca tcggcagaat tgatcgcgat ctccggatga
    11761 ggatggctca ccttatgggc atccacaaag gtctgcgata tttgttcaaa gaggccgcac
    11821 ggggttacgc ctggatgcgc aaacccaacg cggccttcgg tggcttctcg gccctggatc
    11881 ttatgctccg cggtgaaata tcggatcttt cagcgttgcg cgaatggttg gatgcggagc
    11941 gtagtgcatg gtgagtgggc ttgcggtccg caaacgcgtt caatggcagc agacctatcg
    12001 cattatccga tcgatctatc cgccggtcga cctcttcgaa gacattgcgg acccacgcga
    12061 ctgggaagcg cttgctgcgg tcgaggagaa gacgaatccg cgcattcggc tcgagatcgg
    12121 cgatctgggc aagattccgg ctgcccgccg agtgtccggc cccggcgcaa gcttcgtcat
    12181 ggcacccttc gtacattgct cggttctgcg gccgggtcgg ttcaccaatg gcagctacgg
    12241 catttactat gcgggggaca gcgaagtggt cgccgtcgcc gagactattt atcaccacga
    12301 gaaattcatg cgcgccacca atgaggagcc cggttggact gccgatttcc gcatcctgat
    12361 cggcagcgtt gatcgggatc tcgacgacgt cagcgccgtg cccggcgtgc tgcacccgga
    12421 cgattatacc gcgtcgcata tcgagggacg cgatctgcgg gccgcaggaa gcgacgggtt
    12481 ggtttgggac agtgtgcgga tgcgaggtgg gcgctgcatc ggcgccttct ggcccgacgt
    12541 gatcactatc cccatccagg gacggcacta cggctatcat tgggacggta cgcgagtcga
    12601 ttttgtgcgc cagtatgaca cgggacgtgt gctggcagtg acgtgatgtc ccgggcgagc
    12661 cgaccaaaat tgaagttttg aaaattacac tgcccctgca ctaatacccg cccgacatga
    12721 caacagcctc gcccgtcatg aaactgcacg cgtctgaggc gaggaagagt gccgcgccca
    12781 ccatttcgtc cggcgcgcct gcgcgcccca tccagttgag cgtccggacg tagttttccc
    12841 aaccctccgg gtcgccgtcg cggcgagcgg cgttgcggtc cgtgtcgatg aggccgggtg
    12901 cgagcgtgtt aagcaacacg ccgcggggag cgtaatcgcg agcaaggctc tggatcagat
    12961 tatgctgggc tgccttggtc gccgcataaa tggaaacgat cgatttcggc cgcaactggt
    13021 tgatgctgcc gatgttgacg acgcggcccc agccgcgttc ggccatgccc ggcaaggccg
    13081 tctgcagcat ctcgaccgta gatcgaaggt tgacattgat ctgtgtggcg aaatcctccg
    13141 gcgtcacatc gtcgaacgac ccgttgattt gcgccgaggc gttgatcacc agaatatcca
    13201 acggacctgc ggccgtctcc gccgccgaaa tcaaatcgcc gccggcaccg ggcggcgaaa
    13261 gctcgccttg gatcgagacc gcgtcgccgc cggcagcgct tattgcctgt tcgaccccgg
    13321 cggttgcgcc gggcttttgt ccgtgcagga ccacgcgcgc gccataggcc gcataggctt
    13381 gagctatcgc agccccgatt ccgcggcttg agccggtcac cagagctgtc ctgcccttca
    13441 gcgagaatat gtccttatac gtgctcacaa ctgttcctca gacgccgaag agagaggtgg
    13501 ccaggccgcg ctcaccgggg ttacaggcga aaatgccgcc ggagagcggt gcttccgtca
    13561 gcgtcgaggc cgggagacgg gtgcgcgcgc tggtgatgaa caaggtcgca agatcgtccc
    13621 cgccgaaggc cacgctggtg gggcgtggca ccggcagttc gacggcgcga tccagccggc
    13681 catcgggccg atagcggttc acgcgccatc catcccagat tgcacaccag acgccgccat
    13741 cggcatcgac ggcaagcccg tccggacgcc cctccgcctc gggcacggta acgaaaacgc
    13801 ggcggttggc gatgctcccc tccctcgcat cgaagtcgta ggcatagatg atgcccggca
    13861 ccgtatcgac gaagtagaag gtcgaactat cgggactcca ggccagcccg ttggcgaccg
    13921 tgaacccgct ttcggcgcgg gcgacttcac cggtcttcgt caggcgatac aggctgccgg
    13981 tcggccggct cacatcaagg cgcatcgatc ccacccaaag ccttccatgc gggtcgactt
    14041 ttgcgtcatt gaggcggttt tccggtaccc ccggttccgg ctcggcaaac cgggtgaaca
    14101 ggccgcgctc gaagtcgaaa cgttcgacgc cgtcctgcga ggcgacgacc agccgcccgt
    14161 cctcgctcgg aaggacggca ctgacgagct tggctgtgtt gcaggtctcg tttttgccgg
    14221 taacaggatc gaaccgatgc acggccgggt ggagaatatc aacccaatag agccgctttt
    14281 ccctgccgac ccagactggg gcttcgccga gctgggcgcc ccagggcaga acgcattgca
    14341 catcgctctg tcctcccgca cgcgtccgcg gccgcgggcc ggagctgatg gccacggccc
    14401 cgaccgtgcc ggtgatccgt cgcgccgcag ccatcaattc gcggccgacc ggatggatgg
    14461 cggaactgtc gagacgggag gctggcccca gcaccacgag cgctccgagc ggcactccgt
    14521 cgcgcccggc gatcggagca gcgacagtat tgacccctgc gagatgctcc tcgtaggaaa
    14581 cggcatagcc ccgggcgcgt gtcaggacga gatcggcctc gagcgcctgc ggatctgtaa
    14641 tggtctgcgg cgtgaagcga tcataatcga gctgtccagc aagcgagcgg gcgaaggagg
    14701 gctcctgaaa cgcgagcaga gccttgccgg ccgcggtgca gtggaccggc acacgccggc
    14761 cgaccgcaat cagcacgccc aggccgccgc tcgagcgctc ttccagataa accacacggt
    14821 gaccgtcgag gcggcaaagt gcgaccgttt ccccgagttc ggccgaaagg cgttcgagtt
    14881 cgggggcggc ggcgctgacg aggtcgaatt tatcccacac acggtgcgaa agctcgatga
    14941 agcggtgtcc gagcagataa gcgcccgttg cctcgtcctg ccggatcaga cgaaacacca
    15001 tcagcgtctt cagcatgcgc gcaagcgtcg gcttcggcac gccgctcatc ttctgcaggt
    15061 cagcgaagcg cagcggcttc ggagcctccg ctatgaggtc gaggagagcg agacccttgg
    15121 cgagggcggc cgcacccgcc ggtgccccgc gatcttcaag cccgcctaag actgccttgt
    15181 cgtccatgcc gctaccgcct cgtccagcat tcgcatgatc ggccacttcg gctcgaagcc
    15241 gagcgcttca cgaatgcgct ggttggaagt gtgataccac acgccggagc cgggaagatc
    15301 gaccgtcacg agcggccacc cgatcctgtc ggccattacc ggcaggacct cggcgaagtc
    15361 aacaggatcg gtcgctccca gattgaagac gccacccgcc gccttcggat gggacagcgc
    15421 gaggagaacg ccccgggcca tgtcgcgggt gtcggtgatg tgcatcttga acggccggcc
    15481 gttctcgttg cgtgtcagga cgagtgccgg ccgtcccgga tccgccgccc tcagaagatc
    15541 ggccgcagtc ctgttgccga aagcctcctg ctgcttgatt ttcgggcgaa ggaagaagcg
    15601 cggtccggaa aagaagctgt cgggatcgag cagctcatcg gcgttctgcg tatgcgagaa
    15661 gcgcaggatc accgtctcca tcgacgatac gcgtccctgg aacgtcacca gttcctcgcc
    15721 gagaagcttg gtgagaccgt aaggagacag tggctccttc ggatgatcct ccgtaatcgg
    15781 ctggaattcc ggcctgttct ccggatagac ctccccggaa cttgcaaaga cgaagcggcc
    15841 gacctttgcc gcgacggccg cctcggccac gatgcgcgtc ccttcgacat tggcttggaa
    15901 caaccggtcg cggtcgctcg ccagccagga catgaaggct ccgaggtgga gtacggcgtc
    15961 gataccctca caggcgcgcg ccgccgcctc gcggtcgtcg aatgcgccaa cgacttcgtc
    16021 aaagccggca tcatcgatca atgccgagcg cagatcgaag cccctcacct ggtgtcccgc
    16081 ttcaagcaat tgcctgacaa caaaagagcc gaccctgccg gcagaacccg tcacaagcac
    16141 tttcatgtca atctaccgcc ttttccgtct tcggatcgaa gaggtggatt tccgaggggt
    16201 cgaaggagag cgtgagctcg tcgccctctc gcacggggcc ggaatgcgcg atccgggcaa
    16261 tcagaccctt gccgcgttct tcgtcccgag cagcctcgcc gtaagcgttc tcgcccggat
    16321 cgaagtaaat gtatttttcc gagccgaggc tctcgaccaa tgtcggccgc accgcaaaag
    16381 tgacgtcacc ctggccgagc gacagatgct ccggccggat gccgacgatc acctcgccgt
    16441 cacgagcgcc tttctgggtg gcgaagttct ggccgaagag ggtgagcatg ccaccctcga
    16501 tgcgggcgga catgaagttc atgcccggag accctatgaa gccggcgacg aagagattgg
    16561 ccggcctggc gaacagcgtg tccgggtctg cgatctgctg gatgacaccg tcgcgcatga
    16621 tgacgacgcg atcggccatg gtcatcgcct cgatctggtc gtgcgtgaca tagaccgtcg
    16681 tgacgccgat gcgcttgtgc agcgcgctga tctctgcacg ggtgtgaacg cgcagcttgg
    16741 cgtcgagatt ggacagaggc tcgtccatca ggaaggcacg cggctcccgc acgatcgccc
    16801 ggccgagcgc gacccgctgg cgctgtccgc ccgaaagtgc cttcgggcgg cgatcgagca
    16861 gatgctcgac ggccaggatt ctggctacgg cgtggacgcg cttgtcgatt tccgccttgg
    16921 gcatgccgcg catcttcagt ccaaagccga tattctggcc gacggtcaga tgcgggtaga
    16981 gcgcataatt ctggaacacc atcgcgatgt cccggtcccc aggagcaaga tcggtcacgt
    17041 ccttgtcgcc gatcaggatc ttgccgccgc ttgccggctc aagaccggcg aggatcttga
    17101 gcattgtcga cttgccgcac cccgaggggc cgacgaggac gacgaattcc ccgtccgaga
    17161 tttcgagcga gaactctttg agcacgttga gcgctccgta gttcttgtag acgttctgaa
    17221 tgcttatgcc ggccatttca cttctccgcg ccggcagtga gcccgccgac caaatagcgt
    17281 tcaaggaaca ggtagatcag gataatcggc accgagacga acacggccgc cgccgagatc
    17341 tcgttccagt cggtgacgta ctcgcctttc atcgtggtaa tgccgagatt ggccgtccaa
    17401 ctcccctgcg cattggtgag aaaggtgcgg gcataggcat aatcggccca ggagaggacg
    17461 aaggcgtaaa gagcggttgc cgcaagcccc ggcgtcgcga ccggaagcac cacccggaaa
    17521 agggcgccaa gcggagagca gccgtcgacc atcgccgcct gctccaactc gcgcgggatc
    17581 gtgtcgaagt agcccttcag catccatgtg gtgaagggga tgatcagcgt cgcatgggcg
    17641 agaaccagcg accaaaggct cccgatcagc cccatcgagc ggaaaatgcc gaaaagcgga
    17701 atgacgagca gcgttgccgg cagcatcttc gccgtgagaa tgaagagacc cagcgatcgg
    17761 ccgcccttca cgctgaagcg cgacaggctg tagccggcga agaccgaaac aaccatcgac
    17821 agggccacgg aaccgagcgc cgcgagcgtc gaattccaca gccataggag gatcggccgc
    17881 tcggtcgcca ctttggcgaa ggtgctccat tgcgggtcgg ccggccaaaa ggacggcggc
    17941 aactggcgga tttccgcgag cgtcgacagc gccgtgacga acagccaata gatcgggaag
    18001 agcaacacgc cgcagacgac ggcaaggccg gcatagagcg acagtgtttg aagggtggtg
    18061 cgctgcattg ctcgacctcc taatacattg cctgggactt gcggccgagc atcaacaggc
    18121 tggcgacgac gcacagcacg agcgttacga tcccgattgc cgaggcgtaa cccatgttga
    18181 agaagccgaa tgcctgatcg taggtcatga tcgagagcgt ttgcgttgcc ttgagcggcc
    18241 cgccgtcggt cagcactttg atgatcgaga aatccctgaa gacccaaaga acgacgagca
    18301 ccgacgtcac accgagaacc ggcatgagca cgggaatggt aatgtaccag aagcgctgga
    18361 acgcgttcgc gccatcgacc ttggcggcgt tgtagaaatc ttccggaatg gactgcagac
    18421 cggcaagcgt catgatcgag acgaagggat aacctttcca gatcatcgtt atcgccacca
    18481 cccagaacgc ggcagtaggc tcggagaacc agttgaccat ctggctcgtg atgccgagct
    18541 tgatgaagag ccagttcatc aggccgaagg aggaatcgaa gatccaggcg aaaatgacga
    18601 ccgcgatgac ttccggaacg gcccagggca gagccacgaa gagacgcgcc agcgtccgcc
    18661 ccttgaaacg gttattgacc agcagggccg ttcccagacc gacggcgaaa caggctgcac
    18721 tgacgaccag gaccaacttg atcgtgaccc agcacgaatt ccagaaatcc ggtgaggtga
    18781 atagcttgtg atagttttcc agcgtgaacg gcttgcgcgg tgcgctgagc gtcgccatgc
    18841 cgatcttctg gaaagacaag tcgagcgaca cgaacagcgg atagacgatg atcagagcca
    18901 ccagcgcgac ggccggcagc aacagcagat aacccagcca atgctgacgg ctcgggcgtg
    18961 ccagatcgag gaaacgtacg ctcatttttg cctcttggtt tttgccagga cccggcgccg
    19021 ccgcaggcgc cgggtttccc ttcatgtgcc gaggtcggca aacgcctact gcatgtttcc
    19081 ttcaatcgga tccgattgaa ggacaaaaac atgcagcaga tcaaagtgct acagcgacct
    19141 ttgggcgtct gataagacgc acggcgctgt agagcgggat gaggaaagtt tgcgcggtct
    19201 tccgcccgca tcccgcgtct ctactctttg aaatcgatca tgttcatgtc tttaggtcgg
    19261 cccgacctaa agacatcgtg atctactgaa gcgcctcggc cttctcgtgc atcgtcttgg
    19321 cgacggctgc aggatcgaga tcttctatga tcattctctg cgcctcctcc tgaatcattt
    19381 tcgagaactc gttgaactgg atctcgagtc cggtcggaat gcggtcgatc ttgtgctctg
    19441 ccgcagcctt ctgcgacttc gccatcagat cgaaatgtgg aatctgcgcc ttggcttcgg
    19501 tgagatcggc gcgcgggctc ggcggagtcg aggcggcaag cgtcgcgaag ctggtctgga
    19561 atttgtcgga ggtcgcaatt gcgatgaaat cccagacaag ctgcttcttc tcatcggaaa
    19621 tctcgctcgg catcgcgaga atgttggatg accctcccag cggcgggtcg aagggaacgc
    19681 tggcaagctt cagcttatcc tttgccgctc cctgctgcat gatggaatag atccagggac
    19741 cgtcgacctt taaagcgatc tttccatcgg cgaagagttt ccggacctcg cccgccgaga
    19801 ggtcgcgcgg ggtcaggctt tccttgacca cggttttcca gcgggtcagg ccctcgacca
    19861 tttcgggggt gtcgatcgtc accttgcctt ctgcattggt gaagcgtgcg ccggcatcga
    19921 aaagatagct cgccatctcg gcgatatact gcccgccgcc acctttggtc tcgtggccgg
    19981 ttccgaattg gtcgacgatg ccgtcgccat tcaggtcctt ggtggtcgcg cgggccgctg
    20041 cgaggaactc ctcgtaattg gtggggaccg cgacgcccgc ctgcttcagc atctcctcgt
    20101 tatagccgaa gatcgtgccg taatagagca tcatgatgca cacggtcgtg tcctggaaat
    20161 tgcagatgtc ctgcccgctc catccatcga gattgagccc cgacttctcg acccagggac
    20221 caaggtcctc gagccagcca ttgttcgcaa aggtctggaa ttcgaaggag gccaggtgga
    20281 cgatgtccgg cggcgtgccg cctgcaaaga gcgtcgtcat ggtgtcggca taggcgctgc
    20341 gttccacctt ggtccattcg atcgtattac cggggtgctt tgcctcccac tccttgacca
    20401 ccgttcccca ccagtcgccg atgcccttct cgtccttctg ccacgagacg aatttgagca
    20461 cttccgcctt ggcggtgacc ggcagggccg tgcaggccag catcgctgcg accgtcgttg
    20521 cgacggcata tttccggatg attttcatgt tttcctccac tcctccgcgc ttattcgctt
    20581 tcaatttctt ttcagaagcg cgagcgcctc cttcgacggc tcgacgccga gccccggccc
    20641 tgtcggcagg atgtattggc cttcgacgca atccatatct ccgtcgagaa gccggcgatt
    20701 gggctcgaag atcgaatgct ggaactcatg gcagtcgaca ttcgccagcg ccgcgctcgc
    20761 ctggagactt gccgccagga agatgccgga tccgatcgtt gcatgcggga tgatcttgat
    20821 gtgatgcgca tgggcgcatt cgccgatacg catgaattgc gtgatgccct tgtggcccat
    20881 ttccggctgc acgattgcga gcgcgttccg cgcgacgcgc ggtaccatat cgtagacggt
    20941 gcgccattcc tcacccaccg caatggcggt cgggacgctt gccgccaccc gagccagacc
    21001 ctccatgtcc tcggtgcgca ccggcgcctc ggcgaaccac aatccgtgcg gctccattgc
    21061 cctgatcagc gcgatcgctt cgcttgcggt ctgcgcccaa tgcatgtcgc aggcgatgcg
    21121 cgccccgtca ccgagccttt cgcgcagggt ttcgatctca cttgcgaccc cgtcatcggc
    21181 aacgggcgag gcaaatttga aggatgagaa acccttggcc tgccatgatg cggcgagctc
    21241 ggcccgtttt ccgcgcgtgt cttcaggcag cccggaaatg taagcgtcga tcctgtcgcg
    21301 ccttcggccg ccgagcagct tgcagaccgg cataccggcg agcttgccag ccaagtccca
    21361 tagcgcgatg tcgatcgccg cgagcgcatc gacgtaaaag ccgccggtgt agccgcgcac
    21421 ccgcatgaga tcataaaggt cgtcatggat cgccgccgca tcgaatggat cgcggcccac
    21481 ggtgaaatcc gcgagaagat cgtcaatgat ctccatcgtc gcccgcggcg caaccagtcc
    21541 ataggtttcg ccccagccga cggcgccatt ttcagtctcg atacggacga gcacgctccg
    21601 atcgaatgtc ggatagacgg tgcgattgcc cttgcggacc aggtagccgc gcccgttcgg
    21661 ctcctcgccc gggcgcggtt tgccgagata tggtttgtcg cgcggcaagg tgagcgtgaa
    21721 gctctcaatc tttttgacgc gatcgctcat gcgcccgacc ctctatttga tctcccgaag
    21781 gattccacct cgcactcctg caggcatctt tcgatgtcgc gaacggccat tgcgtcgaga
    21841 tcaggagtcg gagcacgcac aatggggttg tcaatgatcc cgcgcaagcc gagcacatgc
    21901 ttggtcagcc gcatgcgata aacggcctgc agcgccaata aaggcagcga cttcacgtaa
    21961 agcgttcgcg cctcgcctcc acggcctgcg cgataattgc ggtcgagagc gacatgcagg
    22021 tcggcgatct cgagcgccgg catcgccgca catgcacccc gatcgtactc gtcaagaatg
    22081 tagcgagcgc ctccgccgcc gatgacgccc agcaaatgct cgggcgcgtc cgcgaggatg
    22141 gcggtgatcg cgggccccgc gggaagggtc tcttccttga catatcgaac agccggaacc
    22201 cgacggacga ccttgaggac cgcctcgggc gacaagtccg agccacgcgg cgcgggcgca
    22261 ttctgaagga taaattccgc gtcgggcatt tgcatcgccg aagcagaaag aaaagcggcc
    22321 accgcgtctg ctcctgcccc gatggacttc gggggttgga tcatgagctg cgtgatcccg
    22381 agcgccagcg cctgcctgcc ataggcgacg acgtcatcaa cggtcgccgc gctggcgccg
    22441 gctatgaccg gcacacgccc atcgacctcg gccgagacgg tttcgagaag cgccaggcgc
    22501 tcctctccgg tcaacatttc cacctcgctc gcaaaaccag gaaacaccac gcccgcaacg
    22561 cccgcatcca aagcgaaccg gacgatacgg cgcatcgcgg caatatcgac cccgctttcc
    22621 gtgaagggcg tcgggagaac cgggagaatt cctgtcagcg gcataattag gtccgtatag
    22681 tgagacttac aatttatatt gtggaccata agcgaaggtg ataggccgtg tcaatccata
    22741 taactttgaa ggagatggcc ttgccggacg ctgcatatga acctgtcacg gtcgtgctcg
    22801 attggggcac cacgaacttc cgggctttcc tggtgaaatc ggacggctcg attgtcgatg
    22861 aaaaaatagg cgaccgggga atccagtcgg tcaccaaagg cgagcacgcg cgcgtcgtta
    22921 gcgaaggcct cgcatcctgg cgcgccgaat acggcccgct cgacatcgtg gcggcaggaa
    22981 tgatcgggag ccgcaacgga tggatcgaga tgccttatgt gccgaccccg gcggcggccg
    23041 gggacctggc cgccgcgtgc cgcaccatcg aacttgcgca gggagaccgg cttacctttt
    23101 taccgggcct gacggatctg acggcctttc ctttcccgga cgtcatgcgc ggcgaggaga
    23161 cccagctcgt cggcttcggc ctgaataggg acatggtcat cgtcctgccc gggacgcatg
    23221 caaaatgggc cgagatcaaa ggcggccgca tcgagcgttt ccgcaccttc gtcaccggtg
    23281 aaatctacgc gacgctggcc agccattcct tcctgtcgaa ggtcgcgacg gccgagcgcg
    23341 accatgccac agcggctttc gctgaaggca ttgcgctggc gcagcaagaa tgcgctcggg
    23401 ccggcggctt gttgacacgg ctctttgccg tcagaaccgg ctggcttgcc ggtacgatca
    23461 caccggacga aatgaagagc cgcctttccg ggctcatcgt cggatgggaa tttgtcgagg
    23521 cgcgggccgg cggctggttc aaggaagtgg acacgatcgc ggtggtcggc gacgacgatc
    23581 tggtcgaggt ctatgaaagg gtggccacgg catttggcct ggagctggcg cccgcaccgg
    23641 ctgacgcggc gatccggggt gccctggaga tctcggggcg tcgctcggca gccgcgacat
    23701 gaaaagcggc gatctcccga ccgaaccggt cacggagatc gccgtatgga cctccggcag
    23761 cctttccggc cggcggatgg gacgaagacg tcaacggcga atgaagagag caaccgtcgc
    23821 gccggccgcg cttgcaatcg cgacgatcat gaaaccagcg acgtatcgcc acggctgttc
    23881 atgaaaccgc cgatgagcgg ttcgccgagg cccgatgagc agatctccta tatcgcctcg
    23941 cgcgaggtag cgcgcagaca cctatgcgct atctgcagat gctccgcctt gaagcccgcg
    24001 cgcgacctgc tgaacgcggg tggctctacc gtgacgcaga tcgcgttcga ctgcggcttc
    24061 tcgtcgagcc agtactttgc cacctgttac aagaagcgct tcggcttttc gccgcaggat
    24121 acgcggcgcg aaccacggct gatggcctgc tctggaggct gacaagcggc gagaacgctg
    24181 ttggctcctg gccggccgcc aggggcatca ggccggatga tgaaggacgc tgagaccgcc
    24241 atccaccgtc agacacgtgg cgttcatgaa agggcattcg tctgaaatca tgaagacggc
    24301 ggcacgggcg atctcttccg ctgtcgcgat ccggccgcca ggatgaagtt tcatcgtcgc
    24361 cgcctcggct gccgccgggt ccgggaaact gttccagtag tcgtaagcct tctgcgtcag
    24421 gacataaccc ggcgccagcg catttacccg cacgcccttc gatgcatatt caatgccgag
    24481 cgctttcgtc atgccgagca gcgcatgctt tgccaccgga tagggaaagg tatgcggaat
    24541 gatggtgaat gcatgcgttg aggcgatgtt gaggatcgct ccgccgccct gctcgatcaa
    24601 attcggcaga accgccttgc agcagttcca ggccccgcgc aggtttacgt caaaacagcg
    24661 ttgccaatcg gcgtcgctca tcgccagcgg ctcggagaac acgttgattc cggcattgtt
    24721 gacaagcgcg ttgatccgcc cgatcgacgt tgcggcgctg gagaccgcca cgctgatcgc
    24781 ttgcgcatcg gtaatgtcgg cctgagcgta gacgagctcc cacccctgct cttgcagccg
    24841 gctcgcttcc ctttcgagca gagggccgtc ccggtcgacg agaaggagtg ccgccccttc
    24901 cgacaggaac acttcggcaa tggcgaggcc gatgccctgc gccgcgccgg tcaccatgat
    24961 ccgtttacct tgaagccggg cactcatccc ttcactccct cagatcggcg catcgtcttc
    25021 ctcaccattc ggccacgctg ccatccgaat ggcgccagac cgggttgcgc cagcgatgcc
    25081 cctccttcgc gcgttccatc acataggcct cgtccacctc gatgccgaga ccgggtccct
    25141 gaggaatgga aacgaagccg tcctcatagg cgaagacgtc cttgttggag atgtaatcga
    25201 ggatgtcgtt cgcctcgttg tagtggatgc cgaggctctg ctcctggatg aaggcgttat
    25261 agctgaccgc gtcgacctgc aggcaggcgg caagtgcaat cggcccgagc gggcagtggg
    25321 gcgccagcgc cacatcgtag gcctcggcca tcgcggcgat cttgcggcat tcggtgatcc
    25381 cgccggcgtg cgaaagatcc ggctgaatga tgtcgacgaa gccgtcggag agaacagatt
    25441 tgaagtccca gcgcgaatag agcctttcgc cgagcgcgat cggggtcgag caatggttgg
    25501 cgatctccct cagggcctcg cggttctccg acaggaccgg ctcctcgatg aacatcagct
    25561 tgaactgttc cagttccttg gcgagaacct tcgccatggg cctatgcaca cgaccgtgga
    25621 agtcgacgcc gatgccgata ttggggccga tcgcgtcgcg gatcgttccg atcgtctcga
    25681 ccgccctatc gatcttctcg ttggtgtcga cgatctgcat ctcctcgcag ccgttgagct
    25741 ttatcgcctt gaaaccgcgg gcaacaacgt cgcgcgcatt gttcgcgacg tcgctcggtc
    25801 ggtcgccgcc gatccaggaa tagactttga tcttgtcgcg gcattgcccg ccgagcaagg
    25861 aatggaccgg ctgcccaagg gccttgccct tgatgtccca tagcgcctgg tcaatgccgg
    25921 ccagcgcact catatgtatg gcaccgccgc ggtagaatcc gccgcgataa aggacgttcc
    25981 aatgatcctc gatgaggaag gggtccctgc ctacgagata gtcagacagc tcgtgaacgg
    26041 cggcctcgac cgtcagggcg cgcccctcta ccacgggctc tccccacccg acgacgccct
    26101 cgtcggtttc gatcttgaga aagagccagc gcggcggaac gatataggtc gtcagcttgg
    26161 tgatcttcat gaaatgcgtc cagttgtcaa agatgtggtt tgatccgaat ggcgccccgg
    26221 cgcaccgtca cgccggaggt gagtgtcgct cgacggcgag agcgagatca cgtgcggcaa
    26281 ggtccagcag ctgccaggaa cagtcacgcg ctgcagtcgc gtcccgcatc cgcaatgctt
    26341 cgaccagttg cctgtgtatc tccacggcac cggcccgcgt gtccgccgcc tcgttggagg
    26401 cctgcagcga gaatttgagg ccggcctgta taatgctcgc cagttgctgg aacacctgat
    26461 tatggctggc cttgaggagc gattcgtgaa aagcgacgtc tgctgccgtg aacttcgcga
    26521 ggtcgccctc ggcatccctc atctgctgcc aggcgcgctc gatctcggcg atttcctgca
    26581 ccgttgcgcg cctcgccgcc aactctgcag caacaggctc gatcgcacgg cgcgcttcga
    26641 gaatacagtt cagaagatcg aactggaaaa tccgatcacc gatccactcg agcacctgct
    26701 gatcgagaat gttccattcg tccttgctgc agacgacggt gccgacgcgt gaacgaccgc
    26761 gcaccagccc cttcgattcc agaatcttca gtgattcgcg tatgaccgtt cggctgacgc
    26821 cgtagcgttc gcacaggtcg ttctcccgcg gtagatagct gcctgccgga taattctcgc
    26881 cgcagatgtc ggcggcaaga gcccgggtga catccttctg cacacgggga cgacgagaag
    26941 gcgtgctgcc cgaatccgtc ggctgatcat gtcgtccttg cactgaaatc tccatgcgcc
    27001 tggcccgcgt actcttgaga cctgaagcga tgcttaccgc aatcgtcccg aagtgacgag
    27061 ccttggttcg ggcatcaata tcagacatac tctatcattc atcatacaag tccaattgac
    27121 aagtatgata ttgacgtctt acacaaatgg cagctgcagg gagcagtcag tcagaacagg
    27181 gagagacatc atgcgcttta tcaaggcctt tgctttggcc ggcaccgtcg caattttcgc
    27241 agcaacatcc gccttcgctt ccgacgtgaa gatcggcttc atcgtcaagc agcccgagga
    27301 gccgtggttc caggacgaat ggaaattcgc cgaccaggca gccaaggaaa agggtttcac
    27361 cctcgtcaag atcggcgccc aggatggcga aaaggttcaa tcggccatcg acaatctagg
    27421 cgctcagggg gcgcagggct ttatcatctg caccccggac gtcaagctcg gtcccggcat
    27481 cgtcgccaag gcggccgcca acgatctgaa actgatgacg gtggacgacc gcctggtcag
    27541 cgccgacggc agcgctctcg aagacgtgcc gcacatgggc atttccgcca cgaagatcgg
    27601 cgaagccgcg ggcgaggcca tcgtggccga gattaagaag cgcggctggg acatgaagga
    27661 agtcggtgcc atccgcgttt cctacgacca gctcccgacc gccgtcgatc gggtggaggg
    27721 cgctctgtcc gtcctcaagg cgaacggctt ccctgaagcc aatatcttcg acgcaccgca
    27781 ggcgaagacc gataccgaag ctgccctcaa cgcatccacc gtcgtcctca acaagaacgc
    27841 gggcatcaag aagtgggtcg ccgtcggcct caacgacgaa gccgtcctcg gggcagtacg
    27901 tgccaccgaa accgtcggca ttcccgcaga cagcatgatc ggcgtgggca tcggcggcgc
    27961 ggaatcagcg atcaacgaat tcaagaagcc ctcgccgacc ggcttcttcg gcactgtcat
    28021 catctcgccg aaacgtcacg gctacgagac ggccctcaac atgtatgaat ggatcgccaa
    28081 cggcaaagag cccgaaaagc tgatcctgac tgcgggccag ctcgctctgc gcgacaacta
    28141 cgaagccgtg cgcaaggatc tcggtatcga gtaatcccct gccccgacag aaatgagccc
    28201 ggcggccaac cgccgggcat ccttccggag cgttgcgatg caggattttc tagaattcac
    28261 atcaatttca aagggctatc ccggcgttca ggcgctttcg gatgtctcct tttccgtgcg
    28321 caagggtgcc gttcacggac tgatgggcga aaacggtgcg gggaaatcca cccttatccg
    28381 ggtgctctcc ggtgaccagg cagccgacac cggtgaaatt cgcatcgacg gcaggccgca
    28441 gcactatcgc tcggtacgcg acgccttcga cgccggcgtc atcgtcattc atcaggaact
    28501 gcaactcgtg ccggagctga cggttgccga gaacctctgg ctcggccgct ttcccggcag
    28561 ggccggtgtc atcgatcgcc ggcagcttat ccgcgtcgtc ggtgaaaggc tcgcggagat
    28621 cggtatcgac gtcgatcccg gggcgaaggt tgcatccttg tcgatcggcg agcgccagat
    28681 ggtagagatt gccaaggcgg tgatgctcga cgcccgcgtc attgctctcg acgagccgac
    28741 atcgtcgctc tcctcgagag aaagcgagat cctgttctcg ctgatcgaca ggttgcggtc
    28801 gaacggtacc gtcattctgt acgtttcgca tcgcctcgac gagattttcc gcctgtgcga
    28861 cagtctgacc gttctcaggg acgggcggct tgcggcccat catccggacg tttcgaaagt
    28921 gacccgcgat cagatcatcg ccgagatggt cgggcgcgag atttccaaca tctggggttg
    28981 gcgcgcccgt cctctcggag acgcaaggct gacggtcgaa ggcgtgtccg gcgccgccct
    29041 gccacacccg atcagtttta ccgcgcgcag cggcgagatt ctcggctttt tcgggctgat
    29101 cggcgcgggc cgcagcgaaa tggcccgcct ggtctatggc gccgacagcc gacggcaggg
    29161 cacagtcctg gtggacggcg ttgccgtacg ggccgacagt cccccgcatt cgatccgcgc
    29221 cggcatcgtt ctctgcccgg aagaccggaa attcgacggc atcgtccacg ggagatccat
    29281 cgaagagaac atggcgatct cctcccgtcg ccatttctct cgcttcggca ttctcgaccg
    29341 cggcaaggaa gcggaacttg cggagcggtt catcgcgagg ctgcgcgtgc gcacgccctc
    29401 ccgccaccag gacatcgtca atctctccgg cggaaaccag cagaaggtga ttcttggacg
    29461 ctggttgtcg gaagagggcg tcaaggtgct gctgatcgac gagccgaccc gcggcatcga
    29521 cgttggcgcg aagtcggaaa tctacgaaat cctttacgag cttgcagcgc aaggcatggc
    29581 gatcgtcgtc atctccagcg aattgccgga agtgatgggc attgcggatc gcattctggt
    29641 gatgtgcgaa ggccgcatcg cggcagaaat tgcaagggaa gacttcgacg agcaccggat
    29701 tctcacagcc gcgcttccgg atgcctccgc cacaaaagct cccatttccg aacaggtacg
    29761 ctaacgatga cgacgtcctt gaaaaaactc cttctcggcg agcagggcct ggtggttatt
    29821 ttcgccgccg cattcctggt ggtatcgctg acggttccga atttcctcac cgaacgcaac
    29881 atgctcggcc tgctgcagtc cgtggtgacc atcggtctcg tcgcctgcac catgatgttc
    29941 tgcctcgcgt cgcgagactt cgacctttcc gtcggctcca ccgtcgcctt ctcgggaatg
    30001 gttgcggtca tggcctcgaa cgccacgggc tctatcgtgc tcgggcttct ggcggcgctt
    30061 gcctgcggca ctgccgtggg tatggccaat ggcgtggtga tcgcgcgctt ccgcatcaat
    30121 gcactcataa ccaccctggc gacgatgcag atcgtgaggg ggtttgctct gatcgcgtcg
    30181 gacgggcgcg cagtcggcat caacgatccg gtcttctatc agctttcatt gtcgaaattt
    30241 ctgtccgtgc ccacgccgat ctgggtgatg gcatttttct tcgtcgtatt cgggttcctc
    30301 ctgaaccgca ccgtcttcgg caagaacacg ctcgcgatcg gcggtaaccc ggaagcctcc
    30361 cggctcgccg gtgtcgacgt ggcgcggatg cgaatctgga tcttcgcgct gcaggggctc
    30421 gtatgcgccg ttgccgggat cctgctggcc tcgcgcatca cctccggcca gccgaatgcg
    30481 gcgaccggcc tcgaactctc ggtcatttcc gcctgcgttc tcggcggtgt ttcgcttgcc
    30541 ggcggccggg cgaccatgac cggcgtcgtc gtcggcgttc tgatcatggg cattgccgag
    30601 aacgtcatga acctgctcaa tatccaggcc ttctatcaat acgtggtgcg cggcctcatc
    30661 ctgctgatcg cggtcctcct cgacaatctg cgctccgtcg ccggccggcc gcgagggtga
    30721 tttccgccac gggaagacac aggccacctt tccgttcccg atttccctgc ccggcaaaac
    30781 aatccagcca gcccaacttc ctgggctggc tttgtgcatg ccgcgccgca gacgcggcgc
    30841 tgctgaatgc tgcgacgagc acagtcacaa ggtaaaaatc gccctatacg ccgcaaccgc
    30901 cagcccccct gacaaacgta cgcaggccat tcgctcaatt tcatgaaata tatttcattg
    30961 atggaaatat attgacatcc tttccatcct agagttacct gcctcttacc ggacttcgag
    31021 gaggaaggcc ggacttcacg aagatagcgg ctgcgtttgg cgcgccgacg cggttattgg
    31081 gaggggcttc ggcctcgagg aggactcttg cgcaattttc tcagcacgac cgcaatggcg
    31141 gtcctagcaa ccacgctttt ttccggcgcg gccgcagccg cggcggaaaa cccgttccgc
    31201 tgcaaaccgg gcgaaaaata cgtcatgaac gtgatggtat ccggcgtcga atactggttc
    31261 ccggtttacg agatgttcaa gcaggccgga cagcagttcg gctgcgagac ggaatacacc
    31321 ggaacgccgg aatatgacgt caacaagcag atcgccagct tcgaccaggc gctcgcccag
    31381 aacccagccg gcatcctggt tcacccgatg aactccgatc cgttcatcga acccatcaac
    31441 cgggcgaccg accagggcac ggcggtcgtg accttcgccg ccgactcgcc cctgtccaag
    31501 cgcgtttcct acatcacttc agacaatacc cgcgagggga tctacgccgc agacaagatc
    31561 gccgaaaagc tcggcggcaa gggcgaatat gccgtgctcg aaaatcccgg ccaggacaat
    31621 catgacaagc gcatcgccgc cttcatcggc cgcatggagg agaaatggcc cgacatgaag
    31681 ctcgtcggcc gcgccgcctc caaccaggac cctaacaagg cctatcaggg ccttacgagc
    31741 cttatccagg caaacccgaa ccttagcgcc gtcttcatgc ccgaagcaaa ttcggcgatc
    31801 ggtgcggcac aggcgaacaa ggaaaccggc ggcaaggtgc tcgtcatgtg cgccgacgtc
    31861 aacgccaata tcctcgacat gatcaaggcg ggagaggtct tcggatcgat caatccgaac
    31921 cagggcatgc aaggctatat gggcttcctc atgctctggc tggccaaaca tccggagctg
    31981 atagacccga tgaacgacgc caagcgttcc ggtttcaatc cgatgagcat tcccgtcgtc
    32041 gacaacggcc tgtcgatcgt taccgccgaa aacgcagacg atttctactg ggacaaatac
    32101 ctgaagcgcc gcggcaccaa aggtatcgag gaataaggtc gcagtgagcg gccgcccgga
    32161 ttccccaggc ggccgatcaa gcgggggaaa aatcgcgatg acatccgaga ccgtgctcga
    32221 catccgcaat gtcagcaagc acttcggcgc cgtgaaggcc ctgacagccg taaacttccg
    32281 gctcgagcgg ggcgaggttc acgcgctctg cggcgagaac ggcgccggca agtcgacatt
    32341 gatgaacgtc atcgccggcg tgctgcagcc gtcggaagga gaaatcctcg tcgagggagc
    32401 gccggtgagg atcgcttcgc ccgcggtcgc gcaatcgctc ggtatcgggc tcgtccatca
    32461 ggagatagcg ctctgcccgg acgcgacgat cgcggaaaac atgttcatgg cggcgaccaa
    32521 ccgccggcgc tcggttctga tgaattaccg caaactggag cgggacgccc aaatcctgat
    32581 gaaccgtctg gcgccgatcg atgtccgtca gaaagtcggc gacctatcga tctccagcca
    32641 gcaactcgtc gagatcgcca aggcgctgac gcttgactgc cgcgtgctca ttttcgacga
    32701 gccgacggcg gcgctgaccg agaccgaagc tcaggtcctc ttcggcatca tccgcgatct
    32761 caaggcgcgc ggcatctcga tcatctatat cagccaccgc atggcggaag tgttcagcct
    32821 ttgcgaccgg gtgacggttt tccgcgacgg acgctatgtt gcgaccgaaa ccgttgcgga
    32881 catcacccct gacgacgttg tccggctcat ggtcggccgc gagatcgatc agctttatcc
    32941 ggagaagcac ggccagtcgg ggtgcgtcgg cgagcccata ttgtcggtca ggaagctcgg
    33001 tgacggcgcg cgtttccgcg acgtcagctt cgagctgcgc cacggcgaaa tccttggcgt
    33061 tggtggcctg atcggttccg ggcggacgga aatcgccgag ggcatatgcg cgctgcgcgc
    33121 ggcgacgcaa ggcgaaatcc ggcttcatga caaggtactt cgactgcgcc gctattccga
    33181 tgcagcgaag gccggcgtcg tctatctttc agaggatcgg aaaggctccg gcatattcct
    33241 cgaaatgtcg atcgctcaga acattgccgc gctcgatctg aaagcgttga cctcattcgg
    33301 cctgctcaat ttccgcaagg aaagatcgct cgccgaagaa ttggcccgca gacttggcgt
    33361 gcggatgggc ggtgtcgata tgccggtctc ttcgctttcg ggcggcaatc agcagaaggt
    33421 gtcgatagcc aagcagctgg ccgtcaaccc gaaggtgatc ctgttggacg aaccgacgcg
    33481 tgggatcgat gtcggcgcca aatcggaaat tcaccgattg ctgcgcgatc ttgcccgcgc
    33541 gggtatcggc atccttgtca tctcctccga actgccggag ctcatcggcc tctgcgaccg
    33601 ggtcctggta gtgcgcgaag gcggtatagc cggcgaggtc tcgggcgatg aaatgaccga
    33661 ggaggcgatc atgcggcttg catccggcat cggtccggag gccaacacga attcaaaggc
    33721 atccgggcat gcggcctgaa gaagcaggag acaggactat ggcagtcgac atattgccgg
    33781 ttgcgcacga cgcgcgcagg ccggcctgga aacggatcgg gacgatgcgc gaggccgggc
    33841 tgatcgcgat catcctttcg ctctgcgtga tcatgagctt cgcctcgccg cactttctga
    33901 ccctcggcaa ttttcgggcg atgctcatgt ccttctccgt cgaggggatt gtcgtcgtcg
    33961 gcatgacgat cctgctgatc gtcggcggca tcgatctttc tgtcggttcc gtcgtctgtt
    34021 tctctatggt gctctccggc tcgctcttcc tgatgggggt cgacccttgg acggcatcgc
    34081 tcgtcggaat tgccgccagt gcggccatcg gatgcatcat gggcttcttc gtgaccgtgg
    34141 tcgggctcaa ccatttcata acgtcccttg cggccatggt gatcgtgcgc ggtctctgcc
    34201 tggtgatcac caaaggcacg ccgctgtcgc tcttcacctt gccgcccgcc ttcaaggcgg
    34261 tcggccaagg gacctttttt ggcgtaccct atgtgatcgt gatcttcatc gccgtcgttg
    34321 ccgtgttcga cttcctcctt cgccgggcaa ccgcgttccg caaggtcttc tataccggca
    34381 gcaacgagaa ggccgccctt tattccggta tcaagaccaa ggacgtcaaa ttctgggtga
    34441 cggtcctttg cacgacgctc tcgggtgtgg cggggaccat ctatatggcg cgcttcggtg
    34501 cggcgacgcc gaccttcggg gtcggcatgg aactcaacat tatcgccgcg gcagtgatcg
    34561 gcggcgcctc cctcaacggc ggatcgggca cgatcctggg cgccattctc ggcatcgccc
    34621 tcctgtccgt cgtcaccagc tcgttgatcc tgctcgacgt ctccgtctac tggcaggata
    34681 tgatcaaggg ttgcatactg ctcgcagccg tttcgatcga tcacatgctg cacaagcgga
    34741 aggctgcctg acatgccgaa cgccaaaccg aaatccacat ccggcccgcg cgaggaaatc
    34801 gtcatcgcca ggcagatgca ccaagccctg gtgctgcatt tcctggaagg cttgacgcag
    34861 gcgcagatcg ccgatcagct cggcatctca catgcgaccg tcaatcgcct gatcaagcgc
    34921 ggccgacagc tcggcctcgt cgagataaag atcaaatcgc ctgtggagcc gttgatcgac
    34981 atcgaggaaa gattgcttgc gcttggcggc atcagccggg cggtggtcgt gccgacagcc
    35041 tccgacaatc cgcagaccgc cttgcaagcg gtcggcgagg ccgcagcaag actgatgctc
    35101 gaggagatcg ccgatggcga cacgatctgc atcaccggtg gcaaaggcgt gagcgccgtc
    35161 gttgccggtc tccacccgcc gcgccggtac gatatcgagg tcattcccgc gacaggctgc
    35221 gttcagggca agcactatac cgacgttaat cacgtctcaa ccctgatggc ggatcggctc
    35281 ggcggccatt ctttccagat ccatgcgcct ctttttgccg acagcgaagc ggaacgaaga
    35341 atgctgctgg gcatgcgcgc agtcgccgac gtcttcaagc aggcgcgtga agcaaagatt
    35401 gccgtggtcg gcatcggctc gatcctttcg gacgactcca gctattacga cctgcatccc
    35461 tcctccagta ccgaccgcgc ggcgatcgaa cagtccggtg catcctgcga gctgctcgcg
    35521 catctcctcg atgatcaagg gcgcgtctgc ggctatggcc tcaaccagcg cctcgtatcg
    35581 ctgacgctct cggaattcgc ttccatcccc atgaagattg gcgtcgcaag cggtccgagc
    35641 aaggcggggc cgatcctgag cgtcatgcgc ggcaaacatc tggacacact cgttaccgat
    35701 caggcaacgg gctcgcgcat actcgaactg gccaaggaag tcggagaaca ttcatgaacg
    35761 gacagcaaat gacgcggatg atcggtcgct ccgggatcgc ggcctctcca gtcggcctcg
    35821 gcacctgggc gatcggcggt tggatgtggg gcggcacgga cgaacgcgag tccgtcgccg
    35881 ccatccaggc ttcactggat gcaggcgtaa cgctgatcga cacggcaccc gcctatgggc
    35941 tcggacgggc cgaagaaatc gtcggcaagg cgctggtcgg gcgccgggac aaggcggtga
    36001 tcgcgacgaa atgcggcctc gtctggcata cgcgacaggg caaccatttt ttcgaccagg
    36061 acggcaaacc cgtgcatcga catctcggcc gcgagtcgat ctttcacgag gtcgagcaaa
    36121 gcctcaaacg actcggcact gactatatcg acctctacat cacccattgg caggatccga
    36181 cgacgccgat cgaggaaacc atgcaggcgc tcgaggagct gcgcgccgcg ggcaagatcc
    36241 gcgcgatcgg cgccagcaat gtgaacctgg aagagttgga gatctatgtg aagatcggcg
    36301 gcctcgatgc aatccaggaa cggtacagca tgctcgaccg ggagatcgaa gggaatctcc
    36361 tgccggtcac aaccgcgaac ggggtggcta cactcagcta ttcttcgctg gccctggggc
    36421 tcctctccgg gaggatcgga ccagaacgcg tgttttccgg agacgaccag cgcaaggcca
    36481 atccgcgctt ctcggcctca aaccgcgaga agatcatgcg tttcgccgaa acgatccggc
    36541 cggtcgcgca gaagcatgag gcgacgatcg cccagatcgt catcgcctgg accctggcac
    36601 agcccggcat caccttcgcg ctctgcggcg cgcgcaatcc ggctcaggca cgcgacaatg
    36661 caagagccgg cacaatccgg ctcaacgcgg acgacctctc ggcgatcgat gccgcaagag
    36721 cggctgcgct ggtaaacatg gacaggtagc ggaccgcccc atgacaagaa cagagatttt
    36781 tgacgggctt cgccggagcc cgaaggtgga cgtgtgcgtc ctcggcggcg gcatcaacgg
    36841 gctcagcgtc tttcgcgaac tcgcgctgca gggattgcgc gttctgctca tcgagaagca
    36901 cgactactgc tcgggtgcga gtgctgcatt gtcacgaatg gttcatggcg gcctgcggta
    36961 cctcgaaaac ggcgaattca cgctggtaaa ggaatcgctc gtcgagcggg accggctgct
    37021 cagaaacgcg ccgcacctcg tcgcgccact tgcgacgacc gtcccgatct tcgacgtttt
    37081 ttccggcctt gccaacggca tcgttcgctt cctcggcctg agccgtcgac cgagccgccg
    37141 cggggcgatc gccatcaaag cgggactttc gatctatgac ctgctgacac gcaagcgggc
    37201 gctgatgccg cgccacaggt ttcgcggccg tcgttcgacg ctcgcgaaat ggcccgctct
    37261 caatccgacg atccgcagtt ccgccaccta ttacgacgca tgggtgcgcc accccgagcg
    37321 gatcggaatg gagctgctgc aggatggcct gtccgcctcg tccgaagcgg ccgcgctgaa
    37381 ctatgcggag cttcgcagaa gcgagagcgg tggctttctg gtggtagaca cgatcgacgg
    37441 ggccggcgtc gagatcaagc ccgggctgat cgtgaactcg accggcggct ggatcgacat
    37501 caccaacggt gcgctgctgc cgcccgacaa cggctgcggc ccgctggtgg gcggcaccaa
    37561 aggctcgcat ctcgttatag acaatccgca actgcgcgaa gcgctcggag atcacatgat
    37621 ctattacgag aacgaggacg gccgcatctg catcctcttc ccctatttcg gcaaggtgct
    37681 ggtcggctcg accgacattc gagtcgacga tcccgagacg gtcaggtgcg aggaagagga
    37741 acgcgactac attctgcaat cgctggcctt cgtgctgccc ggcatcgaga tcgcgccgac
    37801 ggagatcgtc tttcagttct ccggcgtgcg accgctgccc gcgagcagcg acaatttcac
    37861 cggccgcatc ccgcgcgacc atttctgcac cacgatcgag aatgccggca caccggtact
    37921 ttgtatgatc ggcggcaagt ggacgacgtt tcggtccttc ggcgagcttg ccgcgaatat
    37981 ggcattggaa cggctcggcc gtccgcgcca cgtttcgacg gccgaccgcg caatcggcgg
    38041 tggccgccat tttccggccg atcgggacag ctggatctcc gcactcgccc tccgcttcgg
    38101 cctgccccgg acacaggcgg ccgaactgtt ctcccgctac ggtacggatg ccgaaccggt
    38161 ggcgtcgttc atcggtcagg caagcgacgc cgtgatcccg ggtgccgatt attcaacacg
    38221 cgaagttctg ttcctgatcc gcaacgaggc ggtggagcat ttggacgacc tgctcttgcg
    38281 ccgcaccacg ctcgccgttt ccggcgcgct ctccctcggc attctggacg ctgcactcga
    38341 actcctggcg gaggagaagg ggtggtcgac ggcgcgccgg ctgagcgagc gggcccggtg
    38401 ccttgcactc ttgctagaac gccatggcat cgacgagcag acgctcgggg ctcgaacgca
    38461 ccagcctgga gacaaggcca tggcagctgg ctgacaccgc gatcctttgc agccgccacg
    38521 acgcacgtgc actgcgcaac atttgaagaa ggagaagagt atgaaaagca atcgcaaggt
    38581 gcggatgaac cgcatgttca acggcggacg ctgcctggat gtcgccatcg accacggggt
    38641 ctgcaacgag ccgtcctttc tgagcgggct ggaaaacatg gaggccgtgg taagcgcgct
    38701 ggtcgaggcg ggacccgacg ccattcagat gaatttcggc caggccgatc tcctgcagga
    38761 gcttcccggc aaggacaggc cggcgctggt aatgcgcctc gacatgggca atccctataa
    38821 tcgcctgcgt caccgcgaca tgtgggcggt gttgcagaac gaggccgagc ccctgatcgg
    38881 ggcgcttgcg atggatgcgg cctgcgtggt cgtcaacctg ttcatgctgc cggacgaacc
    38941 ggatctcttc cgccaatgcg tgcagaatat cgcccgcgtc cgggcagatt gcgacacata
    39001 tggtatgccg ctcatgatag agccgctcgt catgcagccg gtgaccgagc atggcggcta
    39061 catggtcgac ggcgacgccg aaaagatcgt caccctcaca cgtctagccc gggagatggg
    39121 ggccgacatc atcaaggcgg atcccaccac tcatgcggag gatttccatc gggtggtgga
    39181 gactgcgcgc tgcccggttc tcgtgcgcgg cggcggcaag gaggatctgc ggtccgtctt
    39241 cgacaagtcg tcagccttga tgaaccaggg agcgatgggc atggtctacg ggcgcaacat
    39301 ctaccagcac cccgatccga aagccgtggt gcgcggcttg atggcgatcg tgcacgagaa
    39361 tgccagtggc gaagaggctt tctcgctgta tcggcagggc tgatcggctt tcggaacttg
    39421 ggaggggttt tgcatgggac gctatctttt gggactcgat gccggcaaca ccgtcatcaa
    39481 agcggtgatc ttcgaccggg agggcagtga aatcgcctcc gccgcggccg agggacacag
    39541 ccggatgccc tcgccgggcc atgtcgagcg cggccttgac gagctttggc agaatgcacg
    39601 ccgcgttatc cgcacatgca tagatgaggc ggagatcgac gccggcgaaa tcggggcaat
    39661 cggctgcgcc ggccatggca acgggctcta cgcgctcgat cgggatggac ggccgcttct
    39721 cgctatccaa tcgctcgaca cccgagcggc ggcactggtc gacgaatgga agtcgcaagg
    39781 tgtcggggaa cggacctacc ctatcggtcg gcagcggccc tggccctcgc agaccccgac
    39841 ccttctcgcc tggttgaagc ggcaccggcc ggaggtcttc gcaagcctcg gcacggtctt
    39901 tctctgtaag gacttcatcg tcaaccgact gacgggcgcg cgcgtcagcg acgtttcaga
    39961 catgaccggc tgcggcttgc tcaatctcgc cggccgccac tacgacgcgg cgctcatggc
    40021 ggcatacggg ctgtccgaca gcatggacct tctgccgccg cttgtggaaa gcgccgatat
    40081 cgcaggtcgt ctcaccgagg ctgccgcggc cgagacgggc ctggccgccg ggacaccggt
    40141 ggtcggcggc cttttcgacg tggttgcctc ggcgatcggt tccggggtta cgcgcacggg
    40201 cgccgcttcc atcatcgcgg ggacgtggag catcaatcag gtgatcatcg aaggcccaga
    40261 gctcgatgga ccggtattca tgtcttctac gttcgaccgc gaccgttaca tggcgataga
    40321 gtccagcgcg acatccgcgg caaacctcga gtggctggta cgcgagttct tctccgacat
    40381 tcgctgcgaa gggcgctctc cgttcgatct ctgctgcgag ctggcgtcct cgagcgagcc
    40441 tgcctccgac gaccccctct accatccctt tctctacggc gcccaacagg acggcagcgc
    40501 ccgggccggc ttctacggca tcgccggctg gcacacgaag ggccacctcg tccgagcggt
    40561 cctcgaaggc gtggcttttg gtcaccgcca gcatatcgag gctatacgga aagcgggcgc
    40621 cgacttcgac gaggcgatac tctccggcgg cggctcgcgc agcctggtat ggccgcaaat
    40681 attcgccgac gtgctgggcg tgccggtctc tgtcgcgcgc tcgcgtgaga cgggcgcctt
    40741 gggtgcggca atcgcggcgg gcactggcgt cggcattttc tcggattttg cagagggtgc
    40801 ggcggccatg gtgaaaaccg atcggcacta tcgcccgaat acggcacgcg aaccgcatta
    40861 tgcccggcgc tacgcacttt accgagacat cgccgatgcc atggcgccgc tctggcggcg
    40921 cctctcggca attgaggcca cgacggcggg agcggcggcg tgaatccgca tccgaacgaa
    40981 acatacgatt tcatcgtcgt cggcgccggc tccgctggct gcgttctcgc aaaccggctt
    41041 tcggccgacc cgagaaaccg ggtcctgctg ctcgaagcag gcggcagtga ccgctaccac
    41101 tgggttcatg taccgatcgg ctatctctac tgcatgggca acccgagaac cgactggatg
    41161 atgaggacgg ctgcggagcc cggtctcaac ggacgcagcc tgccctatcc gcgtggcaag
    41221 ctgctgggcg gctgctcttc catcaacggc atgatatata tgcgcggtca ggcggccgac
    41281 tacgacggct ggcgccaggc cggcaacgcc ggttggggct gggacgatgt gcttccctat
    41341 ttcctgaaat cggaggataa ccaccgcggc acgtcggcga tgcatggcgc aggcggggaa
    41401 tggcgcgtcg agcggcaacg cctgtcctgg ccgatcctcg acgcctttcg cgatgcggcg
    41461 gaggagctcg gcattccaaa gacggaagat ttcaatatcg gggacaacga ggggtccggc
    41521 tatttcgagg tgaaccagcg tggcggcgtg cgctggaaca cgacgaaggc cttcctgcgc
    41581 cccgctatga agcggccgaa tctcaaggta ttgaccggcg cagagacgga gcgcctgatc
    41641 ttcgagggcc gcaggacaaa gggcatccgc ttccgcttgc acggacggat ccgggaggcg
    41701 cgagcgaccc gcgaggtcat tctctctgca ggcgcgatca acacgccgaa aatcctcgag
    41761 ctgtccgggg tggggcgacc ggacgtcgtc tcggcggccg gtatagagct ggtccacgat
    41821 ctcccgggtg tcggcgaaaa tctgcaggat catcttcaga tccgcacagt ttttcgcatc
    41881 gaaggggcaa aaacgctgaa ccagctctat cacagcgtct tttcccgtat gggaatgggc
    41941 ctcgaataca tgctgagacg ttccggccca ctatccatgg caccgagtca gctcggcata
    42001 ttcgccagga gcagcccgtc cgtcgcaacc gcagatctcg aatatcacgt gcagccgctg
    42061 agcaccgatc ggttgggtga gccgctgcac aaacaccctg ccgtcaccgt gtcggtttgc
    42121 aatctgaggc cggagagccg gggaagtgtg catgtcacga caggggatgc ctccgccgca
    42181 cccgatatcc ggccgaacta cctgtcgacg gccggtgacc ggctccttgc ggcgcaggcg
    42241 atccgtcatg cccgcagcct gatggcgaca aaggcgatcg cacgatttaa gccggcagaa
    42301 atgctgccgg gcgcggagtt ccaaagcgag gatgaactta tccgccgggc cggcgacatc
    42361 gcgacgacga tctttcaccc ggtgggcacc tgcaagatgg gcagcgatcc gatggcggtg
    42421 gtggaccctt cgcttaaggt tcatggtctt gatggcttgc gtgtcgtcga cgcctcgatc
    42481 atgcccagca tcgtctccgg aaacacgaac tcaccggtaa tcatgattgc ggaaaaagcg
    42541 gcggatgcca ttctccgccg ctagaccacg atttcgaaat ccaggacgaa accgcacgcg
    42601 gcgtcctcat ccgctccagg tgttgggtct cggggtggat gatgcatctt ggaatcgaac
    42661 cccgatgcga tgtgatcgtc cgccggtcaa ctccataacg cgctggaact gaccgacgat
    42721 gcggccgcgc gggacccgga ttgatcctgc ttcaaccgtt tcgtgcgagg cataacttcg
    42781 tttgctggct gctggactac cttcgccagc gtcgatgcca gtccctcgga agccggcttt
    42841 ctcagttgaa gccgtgcacc ctgagcttca cgctgccgac tgcctgcttc tcgaaaacat
    42901 gagaggtcag aacttcatgt tacgagatca cctcgcggag cgagtttggc tcttcgttga
    42961 tcaggctgtc gtgaagcgta cgatgcgaat ataggtgccg tccggcttcg gagcccaatc
    43021 agagcgacca tagcaagtca cacgtgtctc ggaggctgat cggtcaggcg gtggaacgcg
    43081 agggccaaaa caggtagata acggccgttg gaacgcgccg ccgcgctagg gttggctgct
    43141 ggcgacccgt cagcgtcgtt ttgttctcgc tgcttgcccg tttaccctta cgggtccatt
    43201 ctcattctcc gtattggaac acttctggaa ctggtccgag gcctatcgat ggtcgcatgg
    43261 ggtcaatcga tgaactgcgc gggttgcggg ctcgagatcc aaggcggctt tgccttctgc
    43321 cctaaatgcg gcatgaggca accaaagtcc tgccttggct gcggctaccc gtgcccgtct
    43381 gactctgcct tctgcccaaa atgcggcgct ccgacgaacg atgcgggcgc agaggggaag
    43441 cctaccagcc gcgccgcttc ggcgctgact gtgaagatta agcaaccggc cctgcccgcc
    43501 gtcgatgccg accgccggac catcaccatt ctattcgcgg atctcagcgg cttcactgca
    43561 ctgtccgagc aaatcgaccc ggaactcatg caggcactgc aaaatgagct gttcgaggag
    43621 cttaccgagg cggtgcagag ttttggcggc ttcgttgaca agttcattgg cgatgccctg
    43681 ctcgcgctgt tcggcgcgcc gatcgcgcat gaggaagacc ccgagcgagc gcttcgcgcc
    43741 gccctcgaca tggtcgagcg ggcttcacgc atgggcgagc gctggcaggc gcgggccggc
    43801 gcgccgccaa tcctccacat cggcgtcaac accggaccgg tggtcaccgg cggctttggc
    43861 gcgggaagcg ctaaatctta ttcggtgacc ggcgacacag tgaatacagc gcaacggcta
    43921 cagtccatgg cttcgcccag cgaggtgctg gtcgggccat tgacccaacg cctcacccgg
    43981 catgccttcg tctttgagac gctcggcgag accatgctgc gcgggaagac aggaagcata
    44041 cctgtctacc gcctaaaggg gttgcgcgaa gccgcgcgtc ctgcgcgtgg attggaggcg
    44101 ctgggcctca gcactccgct gatcggccgg aaggccgagc tcgagcgtat gttcgcgagc
    44161 ctcgatctgg cttgcagagg ttcggcccaa ctggtgcggc tggtcggaga agctgggatc
    44221 ggcaagtcgc ggctggttaa cgaattcatc gcacgcattg gcgacgaaca acgctttgcc
    44281 gctgtcgcga tcaggcaggc agcctgctcc ccgctcggtg agcagtccta tggtacgctt
    44341 gctgccgtag ttagaagcgc cgccggtatg cggcaaggcg gcccggtagc tgagactaaa
    44401 gcaaggcttt ccgatctgct gggcgaactt ggcctgaacg gagatgaggc ggtcagcctg
    44461 acgccgcttc tgctccatgt cgtcggcctc ggcggtccgg aaggcgcgtt gcggcatgtc
    44521 caacccgaac aactccgcag gcagatcttc tttgcgatcc gcaccatctt cgaaaggcgg
    44581 ctggctctcg ggccgctgct gatagtggtg gaggatttgc attgggccga cgctgtgtcg
    44641 ttggaggcgc tacggttcct gatggaccgg ctggaacagc agcggctgat catggtgttc
    44701 acccatcgcc cgacatttga catggaacaa ctcgattcca ggcgcatcag ccatacgacg
    44761 cttcgtctcg ctccgcttga cgacaatggt gggcgaaagc tgctcgcctc ccttttcggc
    44821 gaaaaatggg accagacgtt gaactcactc ggaagccgga ttctcgaccg cgccggcgga
    44881 aacccgctat ttatcgagga gattgtgcgc ggcttcattg aggacgggat cctggagcgc
    44941 gacgggcttc attggcgggc tgcatcaagt gaagcggcgg tcgagattcc ggcgagtatt
    45001 caggcaatat tgctcgcccg ggcggacagg ctgccgcccg aagcgcgaag gctggcccaa
    45061 gaggcggcgg tcctcggccc acgcttcgac gcaacgctgc ttgccgcgat ttcagcccac
    45121 ccaaagaaca tcgagacggg gctagatatt ctctgtgatg cggagatcat cgaggaagtg
    45181 gccgctggcg gttcaatcgc gtctcgctcg tatcgtttca cgcaggccct gctccaaaac
    45241 gtgatttacc aaaacctcct tctgcagcgg cgcaccgaaa tgcacgggca ggtcgggatg
    45301 gcgttggaac aatcatgcgg gcaagaccca gagcgcctcg aggacctgct gctcctcggc
    45361 catcatttca gcctgagccc gaacagggca aagggtgcgc gctatctacg ttcggccggt
    45421 gaccgggcac gcgcggtcta cgcaaatgac gacgcgatcc ggcactacca acaggcgctg
    45481 acggcgcttg ccgacgagcc ggaacccgtg gaactgaggc tctctctgcg cgagcgcatc
    45541 gccgatcttt gcggtacgac ggggcggcga gaggcagccc atgaacacta ccggacggtg
    45601 ctcgtggctc gccgagccac aggcgaccgc gctggggcgg cacggatatt gcgcaaactc
    45661 ggccgactac tttggcaagc cggcaaaaga acccacgccg aggcacacta tgccgaagcg
    45721 gcgctgttgc ttgaaggaac tgacgcgcga atcgaacagg cgcttctgct ccaggagcgt
    45781 ggtcgtctgg catttcgcat cggtgagcac tccaacgcca taaaatgggc tgagaaggcg
    45841 ctcgaacagg ccgagtcgct gccggttgat gccgacgagg ggaccaggtt ggaggcggca
    45901 cacgcgaccg cagaggcgct caacacaaag ggggtcgctc tggcgcggct cgagcgatgc
    45961 cgcgaagcgg tgatagaggt ggagcagagc gtcaacgttg ccgaggctgc cggcctgctc
    46021 agcgccgcgt gccgtggcta cacgaatctt ggcgtgctct acactgtgat cgatccggca
    46081 cgggcaatcc aggtgtgtcg gcgaggcctc gaggttgcgc gccgcattgg cgatctcggc
    46141 tttcaagcgc gtcttctcgc caacctggct gtcgtcagtt gcaccttcac cgaccgctgc
    46201 ggcggcgagg gcgttcctgc cgccgaaaag gcgatcgaac tagaccgcgc actcgaccag
    46261 cgcgagcatc tgcctgtccc gctcatagtc cttggacaga ttcatcagtg ccatggggag
    46321 ccggaactcg cggcacgctg ttacaatgag gcactagaag tggcgcggga aacaggcgag
    46381 ccgcaaatgc tttttccgtg ttatgacggc ctagctacac tgagtctcga cgtcggcgat
    46441 atgggcgagg ccgagcggta cttttccctg gcacaggatg tatgcaacca gcacgggctc
    46501 gatcccgaag ggctggttgt cctgccgttt ctcgattagc cgtaggagaa actggacatc
    46561 cgagcgtcgt ctcgaaggcc cgcctgcagc cagcgactat gcgccaaata ttattgctca
    46621 ttgcgattac ccgtgacggg aagattacct atgggaacat cgccattaac aattaccttt
    46681 ggcagaagcc gctcttgatc gccgcagtct tcaatggcca ttctcacagg cgccacacgg
    46741 cacaaaccga cagcgctttg cgcggagaag acgtcgaata gctggccgtc ccgacacacc
    46801 ccatcaagcg cacgcggctt tgtttccaca tcggacaatg ccagacttgc tcgcgccgta
    46861 gagaaagctg ctgttgcccg cagcgccgtc gaagctggcg agaagcgggt gcagatgctg
    46921 ctcacccttt cagtccggga tggtactggc cggccgccca tgaaccggcc gtggttagtc
    46981 ggctagcgcg cgggctgcgg ccaggacttc ggtggctgaa ggaaacttcc ccaacccggc
    47041 tagcccatcg gccgcgcact caatgtaggc ccagcggacg aagccggccc tatcaattaa
    47101 aaattggccc ttaagctggg gccactgccg ctccatatcg gcttgatccg tttcattata
    47161 cttgtagttg tctagctttc caatggcctc ggccgcatgc gtgatcggca gcggttctgc
    47221 gaacaagccg tctgggttga tcagggtcgt atccagcgcc ctcaggaact ccggcgtcgg
    47281 tatgggtctt gggacgccgt atgcttgatg cgtcgagagt tccggatcag ccgccagacg
    47341 gaggcgtgtg ggcctgaatc ggaaataaag ctgggcgttg tctggggctg tagccacaac
    47401 tccgagcgtt tcaactcctg cagacttaag tgcagactct gatgctgcga tctgggcaat
    47461 tgcgcggcgg cagaatggac accagaggcc aatgaacagt gcaagaaaaa gtggggtcct
    47521 cccacgatag tcggccaagg agatcgtccc gctgccgtcc actgcgggta aaacaaaatc
    47581 cggagcgggt tcgcctggcg tgacaggttg cgaaatctgg gtgatgctca tgggaacgac
    47641 tcctcgcaaa catcaaatca ccataatgaa gcagcgcagg tcggcgcaaa gattggcggt
    47701 cgatgcaatt cagcggacac aaagcatcgc ccattcgatc cggcccacgg agacattttg
    47761 agaacgatgc taacgagttt acatgtctac ccgtcactaa gacaatgctc tcaaggttgc
    47821 ttctccgcat ggacaccgct atcgggttct ctcgtctact gtaaccgacg atgcctcgcg
    47881 atcgtcaggc gcatattgcg cgtggacagg cctcattggt cacccgccag gctgcctccc
    47941 tgttgaggac acgcgacccg atcctcgatg atgccgatgt cggacgcact ttcgtgcgcg
    48001 ctgtacctcc acgcgaacca cgcgtcgtgg gccccgctgt ggccgacaag ttccaatggc
    48061 agggcgcttt cgttcgctgt gcgggttaac agagctgagc ggcgtctgaa actgtcattc
    48121 cagagcaggc tcgaatccta gtcgttccga cgtcccgaac tcaccattgc cgcttctgag
    48181 gggatgagtt ccggtcgata aatgattcga tccatcaagc ctggaacgtg cacatccctc
    48241 tcagcaagcc gtgtaaaggc tcgtgaagac cggctccctt cgtccccttg cggaacttcg
    48301 ctcgctctcg gccgaaatca cgcccatccc ccgagctgac tttcggcgtc acagggtgga
    48361 atgtccgaaa gttgccgggg cagtcattgc cccagcagga tgtcggctgt tcaatgccac
    48421 gagggttacg tgatcaagcg cacaggcgat ggggcgctgg tcgagttctg cagtgtagtt
    48481 gcaagtggag cgtgacggct gtaccgtgaa cgtgcaagat gcgcaaagct gcgcgctgct
    48541 gcatgttcct tatgtttgcc gactaaagct gaaacatgca gcgatcgaaa gtgccacagc
    48601 gtgctttgcg cgtcggcttg cacgcgcggg actgggcagg acgtgccgta atggaacttg
    48661 tcgtcgctct cggtctgatc gtcttcaagg tcgcgttgct gatcgcgatt ctgttgttgc
    48721 tacccctgcc gctaacgtgg ttggaacgta agatagcggg gcacatgcag cagcggatgg
    48781 ggccgatgcg cgtgggctgg cacggtcttc tgcagccggt agcggacggt atcaagctcc
    48841 tgaccaaaga ggaccacata ccggccgagg ccgaccgctt cctgtttaaa ctggctccga
    48901 tcctggcgct tgccccgccc ttcgtggtgt ttgccgcaat ccccttcggc gaaactgttt
    48961 cggttcttgg caacgagatc actctctaca tttccaacct gaacgtagcg ttgcttttcg
    49021 tcttcgcggt cattgggctg gaggtctatg gcgtcatctt cggcggctgg gcggctaaca
    49081 gcaaatatgc ggtcctcggc tctctgcgga cctgcgcgca gatgatcagc tacgagattc
    49141 cgatggggtt cgcggtcatc ggcgtcgtca tgctggcgca atccatgagc ctgctggaca
    49201 tcgtgcgggc gcaaagcgac gtctggaatg tcgtttatca gccgatcgga tttttcgtgt
    49261 tcttcgtcgc aggccttgca gaagcgcagc gaattccttt cgatcttgcg gaagccgaag
    49321 gcgatctggg agccgggttc cacaccgaat atagcggcat ccgcttcgcc ttgttcatgg
    49381 tcagcgaata tgtcgtgatg gtgctggtgt cggtcctcac tgtaatcctg ttcttcggcg
    49441 ggtggaacgg cgtgctcatc ccactgccgc cgctcctctg gttcttgctg aaggttgcct
    49501 tcttcatcta tctgttcatg tggttccgct ttaccttccc ccgctaccgc tatgaccaac
    49561 tgatggcaat cggatggaag gtcttgcttc ccctgtcttt ggcgaacata atcatcagcg
    49621 gtgttgtttt ctcctgatgc atgccgccca gaagctctgg gtacggacat gcaagaagac
    49681 tctcaggagc cgcagcgagg cggccatgtc gcacgcactg gacaaagctg gaagatggat
    49741 cggctgggct ttcttcgccg atctggcgaa tggtttggct ttgaccttcg gctacatgtt
    49801 ttccaaaccc gttaccatgc aatatccgga caaggagaag tggctgccct attcgcgtta
    49861 tcgcgggcac catttcctca aacgtgacgc cgagggcgag atcaaatgcg tcgcctgcga
    49921 gctctgtgcg cagatctgtc cctgcgactg catcgaagtg gtcccctacg aggacgagaa
    49981 gggcaatcgg cgcccggcca aattcgagat cgacacagcc cgctgtctct tctgtgggct
    50041 ctgcgaggac gcctgcccgg cggacgcgat cgctcttggc caacaatatg aattttcgag
    50101 tttctcctcg cgcgacttgg tgatcggccg tgacgatctg ctcgccaagc cgggcaaggc
    50161 gatgaccggc ggcggcgtcg tcgctgcgcg cctgagcacc gaacgcgacg ttctggtcga
    50221 ggcgagcgag ccacgcggtt acaattggtg gcggaatatt cgacgaaagt gacggcgcgc
    50281 ccggcgtcgc gccggagcag gactggaggc tctgatgcac atctgccaaa tcctgaggag
    50341 caagtctccc gaaatcttct cggtcacgcc ggaccacacg atggtggaag tattgcagct
    50401 gtttcgcgac aggaatatcg gctttgtcgt cgtcggccgt tcgccagggg aatgcttggg
    50461 cacactctcg gagcgggact gctgctatgc cgtggccgag tacggctccg aagcacccct
    50521 catgcgggtg ggagaaatca tgaaccgcac tgtcgcgacc tgctcgacgg aggatttcct
    50581 cccgttcgta atgtcgatca tgacggagcg gcgcacacgc catgtattgg tcatggacgg
    50641 caacgatgcc gtcggcgtgg ttagcatcgg cgacgtggtc aaacaccggc tcgaagaggc
    50701 attgcaagcg gagcgggaca tgcacgatta catttgcgga gccaactatc gctgacgaag
    50761 tcacctgccg cggattgcct gagagtggac cccttcagca aggctgcagt gaccctctgc
    50821 ccgcaaatcc ggatgcaatc agacccgatc ctcctccaga gcagacgctg cctttgcgca
    50881 tgcgcgaatc tccaccggac atggatactc gccccgccgc atcagactgt tgagccgcag
    50941 ggcgcggtag ttttcgggaa cgaacacgag cccgtccgga aagcgcttgt taaccttgag
    51001 cttcgccgtc agctcgcccc gggcagaccg cacgagcacc tgatcgccgt ccgagaggct
    51061 aagacgagcg gcatcccgag cgctcatctc gataaacggg tcatccgcga ccgaattcag
    51121 ggtttgcgag cgttcggaaa catagccatt gtggaacagg cagttgccgg tgatcagctg
    51181 gagcacgtcc gtcacccggg tcgggggcgg aggagcgaag ggcgcaccgg cccaaggcct
    51241 cggggctgac ctggtaaatg caccgtcgcc accaagcccc tcccatgtca agccttcata
    51301 ggcggaaacc aaccgggtta tctcatcgaa aacggcggca ctggccgata gctgcagcgg
    51361 ctgctcccgg agcgccgcga taaagtcgaa gatcgccaga ttgctccggg cgtcaaaagg
    51421 cggctcgcgg aatttgcgaa gcgcctggat acggccttca ttgttggtga acgtgccgga
    51481 ttcttcgccg taaccggcgg cgggcagcac gacgtcggcc aatcccgccg tatctgtgaa
    51541 aaacgcctcc tgcacaatca gaagactggc ggcaccgagt gcgcgctcga cgaactcccg
    51601 gtcgggatag gacatcatcg ggtcgcttcc gaccacatag agcacgccca tccgcccgtt
    51661 ttcgcagagt tccagcatcg cgtcgacatc ggcgcccggt ttgcgaggga tctccgcgcc
    51721 ccagctccgt tcgaacttcg tgcgcgtggc ctcatcggcg acggggccca gccccggcaa
    51781 aactcccggc agtacaccca tgtcccaggc gcccatctga ttggcacgat cgaagaggaa
    51841 ctgcatcgag ggttccttgc cgagcaggcg caggagctgc agaaggttgc cgagctgctg
    51901 cagcgtctcc cgcgccagcg gcgatctcag cagatcgacg tttgccagga cagtgacgtt
    51961 gcgaccttcc ttgagcatta cgaccagacg gtccaacgcg tcatttgcgc ccgccgcgga
    52021 actgggggtc ttcgcaggga tgtcgcccgg caaaccctca tcggccacgg ccgcgagagc
    52081 agccacgacc gcggccaggc cctgagcctc gccgccgggc tgaacgcgaa gaaccgcccg
    52141 ggcatcggcg tcgagccgcg atggccgcgc cgaaagcatg agcaagccgg tatcccgccg
    52201 ccgcgcggca tcgcgcagga ggtattcggt gaccgggttc tcctcggtca cgttgccacc
    52261 tacgacgagg acgcagtcat tgccgatcac ctgttctaga gcgccacggc tgtaaaaact
    52321 tgctaccagc ggagccagga tgtcgagagg cgtggaccag cgggacgagc agtcgacatt
    52381 attggtgcgg aacaccgtcc gcatcagctt ctggaactgg tagagcacct cgttcggcag
    52441 acgcggcgag atgagcccgc cggcggccct gccctccacc gccgcgaggc gctggcggag
    52501 aaattcgccc gcttcttccc atgacaccgg cgtgagcgcg ccgtcgcggc gaatcatcgg
    52561 ccgcttgatg cgatcccggc cctcgatgaa atcgaggccg aagcggccgc gcacgcagag
    52621 ggtttcgcgg ttgaccccat gctcccagtc cgagcggacc cgcatgaact cacccttgcg
    52681 cgctccgaca gtgagctggc atccggtgcc gcaatgcggg cagatcgtgt cggtctcggc
    52741 gagatcccag ggccgtgccc tatagcgata ggggaagctc atcagcgcgc cgaccgggca
    52801 gacctcgacg cagttgccgc actggtcgca gcttgcaaga ctcccttcga aaccggtgac
    52861 ggcggtgtcc atgccctttt cgaccgtgcc tagcgccacc gcgcccacga cctcctcgca
    52921 catgcgcacg cagcgctggc actggatgca ccggttgaca ttcatgatga tcaccgggct
    52981 cagacggatg tccttcgaat ggaacacacg tttggggtcg cggaaccggc tttcgccggg
    53041 cccatacgcc atgaccatgt cctgaagctc gcattcgcca cccttgtcgc aaatcgggca
    53101 atcgaggggg tgattggcga gcagcatgtc gagcatggac gcgcgcgttt cttcgatcag
    53161 cggcgtattt gtccgcactg ccatgccgtc cgctgccacc gtggcgcagg ccggttgcag
    53221 ccgccgcagt ccctcgatct ctaccagaca catgcggcag gaggcgagtg gcggcagccg
    53281 tttccaatag cagaaggtgg ggatctcgat gcccagtcgc tcggcggcgg cgagcaccgt
    53341 cgagccagcc tcgacctcca gggtttgttc gtcgatcgta accttgacca tacttcctcc
    53401 cagaccggcc cggtgcccct cagtggaaag ggcacctccg ctcttcgata tgggcgacga
    53461 actcctcgcg gaaatgcttg agcgcggcgc gcagccccat ggccgcgccg tcgcccagtg
    53521 cacaaaacgt gttaccgaaa atgcccttgc agagcatctc caactgctcc aggtcgccgg
    53581 tttcgccctc gcctgcctcg atgcgccgca ggactttcac ggtccagttc aaaccttccc
    53641 ggcatggcgt gcacttgccg caggactcat ggtggaagaa ctcgatgatc cgcgttgcga
    53701 tcttgaccat gcaggtcgag tcgtcgatca cgaccacgcc cgccgaaccg agcatcgaac
    53761 cggcggcggc aagcgagtcg aaatccatgc ccacctcgag gtcgctctcc gggatcaccg
    53821 gcgccgagac tccgccggga atcaccgcct tgacctttcg ccccggcagg ggtccgccgg
    53881 cgtattcctc tacgagttcc cgcagcgata tgcccatcgg cagctcatag aggccgggtt
    53941 tgcgcacctg accgctcaca cagtagagct tcgggccggg actcctgtcc ggccctatgc
    54001 cgcggaacca tgccgatccg cgcatcacga tatgcggcac gcaggcaagc gtctcgacat
    54061 tgttgatgac cgttgggctg gcatagaggc cggctacagc aggaaacggc ggcttcagtc
    54121 gcggctgcgc ccgcttgccc tcgagagact cgagcattgc ggtctcctct ccgcagatat
    54181 aggcgccggc accgcgatgg atgtggacca tgaatttgaa gttggagcca agaatgccgg
    54241 tgcccagata gccgttttca tgcgcctggg cgatcgcctg ttccatgcgg cgaatagccg
    54301 tcacatattc tccgcgaatg tagacgtaag cggtttcggc cccgattgca taggcgctga
    54361 ccgccagccc ctcgatgagc tgatgcgggt cgcgctccat gatgatgcgg tccttgaagg
    54421 tgccgggttc cccttcatcg gcattgcagc agagatattt cggcttgccg gccgctttcg
    54481 gcacgaagct ccacttcatg cccgtcggga acccggcacc cccgcggccg cgcaggttgg
    54541 actccttgac gagctcgacg atctcgtcgg gtgtatattc gccgagtgcc ttcgtgagcg
    54601 cttggtagcc gccgccgacc tggtaggtcg acagcagatg accgtccggc acatcgacat
    54661 ttctgagcag gaccggctcg aacatggctt actctcctgg cgacggcgga tgagcgcgct
    54721 cgacgctcgc cacccgctcc gccgcgcgaa agctctccag catcgcttcg agccgcgcgt
    54781 tatcaaggtt gccgtggtaa tcatcgccga cctgcatcac cggagccatt tcgcatgccc
    54841 cgaggcattc gacggtcgaa agcgtgaaca caccgtccgc cgtggtctcg cccttcttga
    54901 tccgcaacgt cgtttccaga tgcttcagca gcgcctcgga tccgcacagc atgcaggaga
    54961 cattgtcaca gagttgcagg tggaacctgc cgatcggttc ggtatggaag agcgtgtaga
    55021 aggtcaccag ttcatagacc caaacgcgtt cgacgccgag gatctcggcg acgtcttcga
    55081 gcaccgggcc gggcagatga ccatgctcct tctgcgcgat catgagcgcg ggcatgatcg
    55141 ccgatcgccg atcgggatat cgtgctgccg ccgcctcgat ctcttcgcgc atcgtcatcg
    55201 cgtccaaacc tccctgctac ttgtccacct ccgccatcac cgggtcgaga ctgccgagca
    55261 cggcgatcat atcggcgagg taacgtgcat tggtgacccc gaagagcgcc tggagattga
    55321 cgaaggacgg ggccctcacc ttcatgcgga acggctttgg cgatccgtcg ctgatgatgt
    55381 agaagccgag ttcccccttg ggcgcctcga ttaccgaata gacttccccc gcgggtacgt
    55441 cgaagccgta ggcggagaga tcgaaatgct ggatcagtgc ttccatcgag caatgcacgc
    55501 gctctttatc gacggggaag gcgatcgtcg gaatatcgac ctgaaacggc ccctccggca
    55561 tctgctccat gcattgttcg atgaggcgga tgctctctcg catctcgtcg acccggcaaa
    55621 gccagcgcgc atagcaatcg ccctcctcgc gcgtgatgac gtcaaaatcg agccggtcgt
    55681 agatttcata gggttcgtcg cgccggatgt cccagtcgac gccggaggca cgcaggttcg
    55741 gtccgctcaa gccgaggtcg accgcgtccg ccgcggagat cacgccgatc ccctgagtac
    55801 ggctgagaaa cacccggttg ttctctatca ggcgctcata gtcgcggatc ctgttcggga
    55861 atatctcgca gaactcccgg atcttcggaa ggaacccgtc gggcaggtcc tcgcgcaccc
    55921 cgccgacgcg gcagtaggac gtgtgcatgc gcgcaccggt gatcatttcc aggaggtcca
    55981 tgatcatttc gcgctctcgc atggcgtaaa gcagcgcggt catggcgccc aggtccatcg
    56041 gcagtgcgcc ggtgatcagg agatggccgg aaatccttgc gagttcggcc atcatcacgc
    56101 ggatgtattg cgcccggatc ggggcctcta tgccgagcag cttttccacg gcgagcgcga
    56161 aggccaggtt gttcgaaggt ggacagagat agtcgagccg gtcagtcagc gggaagattt
    56221 gcgtataggt gaagctctcc gccagctttt cggtgccacg gtgcagatag ccgatatggg
    56281 ggtcgatgcg ctcgacatat tcgccgtcga gttgcagcac gagccgcaga accccatggg
    56341 tgctcgggtg ttgcggaccg agattgagaa gcacctcctt ggtattgagc gcttcgcctt
    56401 ccggcctcat gagctcggtg acttcggtca tctcaaactc tccggcgtct aatggcctcc
    56461 ttggggtata tctctagtgg cgaggtccgg ctgcgttggc ggcggaccct cggctccaaa
    56521 ggggttcagc ttgtccttgt agcccctcaa ggggaaatcc ttccgctgcg gaaagccctc
    56581 aaaaccttcc cacatgtaga tccggcgcag atccggatgc ccttcgaagc ggatgccgta
    56641 catgtcccag gcctcgcgct catgccaatt ggcggttcgc cagactcccg tgacagaggg
    56701 aacatgcggt gggtcgccga gccggcactt gatgcgaacg cgccatttgt tattcagcga
    56761 atagaggtgg taaaccgtct cgaagcgcgg caagtcggga taatgatcga cgccgcagat
    56821 gtcagagaga aaactgaact gaagcgccgg atgttctttc aggaaccgac agaactcgac
    56881 gatctgctcc ggtgggacgg caaaggcatg aatgccgtgc gcagcgccga gaccctcgac
    56941 tgctcctacg aagctcccga tgatcgatag aagatcgaca ggccgctccc cggtcatgac
    57001 gctacaaccc gccccagggg cgtcccggtg agtgcgcggg atgtcttgat cttctcctga
    57061 agcaggagaa agccatgcat cagcgcctcc ggcctcggcg gacagccggg cacatgcacg
    57121 tcgacgggga cgaaggtttc cgatccctgc accacggcat aggtgttgta aactccaccc
    57181 gaaatcgcgc aggtccccat cgcaatcacc cagcgcggct ccggcatctg gtcgtaaagc
    57241 cggcgcacga cgggcgcgaa tttgcgcgtg acagtgccgg caatgatcat cacatcggac
    57301 tgccgcggag aaggccggaa caccacgccg aaccggtcca ggtcgtagcg cgcgcagccg
    57361 gccgagatca tttcgatggc gcagcaggca atgccgaagg tttcgggcca caaggccgac
    57421 ctccggctcc aactgatgat gctttcggcc gtggtgaaca gtacgctgtc gcggatcgca
    57481 tcgtttactc ctgccattcc agcgccccct tcagccaggc ataggcgaag cccacaagaa
    57541 gcagcaacat gaagacgaac atctcgatat agccgacgat gccgatctcc ttcaggacga
    57601 ccgcccaggg aaagaggaac atcgcttcga catcgaagat cacgaggagg atggcgagga
    57661 taaaaaacgg aacccggaag cggccacctg cggcctcacc cgccgcttcc ataccgcatt
    57721 cataaggggc gttcttctcg ggatagggat tggacggacg cagcagcgag gagacgaaaa
    57781 gcgttgccgc cgccaccagg actatcccgg cgaccatgaa cagaacaggc aggaactcca
    57841 ttgccgtcat aacgtctggc cttggtcaac cacgctcggc cgcgatcaac cccctttgcg
    57901 accaggaagc cggcgctcgc cggcggaccc tggcaatcca ttttacctgg cacgagtcta
    57961 ttccgtcgag ccggtcaatg caaatccaat tgattagtaa gatctgatac gagtcggact
    58021 gcctgcagca atttggcgtc gagggtacag cgaaaacacg ccttaccctc caaaagccgc
    58081 ctgttgagct agcctcaaga accacgccgg aaacaggcca atgccgatgg tgccgacggc
    58141 ggtgaaggcg agcgtggcgc ggacgagcgg cgtcagcgca gggtcaaacg tcctttccgg
    58201 ctcgcgcatg tagatcacca tcacgatgcg gatatagaag taggcggcga tgacgctgag
    58261 cagggctgcg atcaccgcta gcgcgacaaa accgcgctcg accagcgcga ccagcacata
    58321 gaacttggcg aagaacccgg ctgtcggcgg aatgccggcg agcgagaaga gatagaggag
    58381 catcagaagc gcgagcccgg gatggaactt ggcgaaacct gcgtagtcat cgatgacttc
    58441 gccggaaaaa tctccgttcc gcatcatgat cacggcgccg aaaatgccga gattcatgaa
    58501 agcgtagatg agcagataga gcatcacgct ggcgatcccg tcctggccgc cggccaccac
    58561 gccgaaaata gcgaacccag catgcgcgat gctggaatag gcgagcaggc gcttgaaatt
    58621 atcctgcacc agcgccacga aactgccgag cgccatcgtt gccaccgcaa tggccgcgac
    58681 gatgatccag gcgttcgagg cttcgacgag cggattaaga aacaccctga ggatcaccgc
    58741 aaacccggcc gccttgggtg cgaccgacat gaacgcagtg atcgtcgtcg gcgcgccttc
    58801 atagacgtca ggcacccaca tatggaacgg cacggcgccg atcttgaaga cgagccccgc
    58861 aacgatgaaa acgaccgcca gcagcagggc gggatcgaac ggaccgccgc tcaccgcctc
    58921 agccatcctg tccagttggg tcgtaccggt gagcccgtag atgagcgaga cgccataaag
    58981 gaaaatcgct gtcgagaccg cgccgaggat cacatatttc aaagccgcct cgttcgatcg
    59041 ccgttctttg cgcaggaagc ccgtcagcac ataggtgcag agcaccatca gctcgaggcc
    59101 cacatagatc gacaggaggt cgatcgccga ggccatgatc atcattccaa gaagagcgaa
    59161 gagcagcaga acataatatt cgctcctgcc gattccctct atttcggcgt acttacgcga
    59221 cagaaagaag gtcaggacag tcgccagata aaacaccaac ttgaagaaga cggcgaagct
    59281 gtcggaaatg aacatgcctg cataggctgg ccgtatctcg cctgccagca tgagcgtggc
    59341 caccgcggcg aggagcacga tcgcgactgc ggcccacagg agcagttcat cccgtccctt
    59401 gcgcacaagc tctccaacaa tcagcaggat gcaggcaccg gtgaccacga tgatctcggg
    59461 gacgctcgcc aggacccatt ggagaagggc gacagcagtc attgaccgat cccttcaccg
    59521 tgtacctgca ccagtagatt tcgcacagac gcatcgatga tcccgaggaa cggtcgcgga
    59581 tagagcccga cccaaagcac gaagatcgcg agcggcagga tggcagccat ctcgcggccg
    59641 ttcacgtcgt gtatcttata cttggcactc acactcggcg gaccaagcgc caccttcccg
    59701 tacatgccga gcaggtaggc agcacttagc aacgcaccca ctacggccgc ggtgcccgcg
    59761 gcgaggtttg ccgcaaaccc acccgacagc accagcagtt cgcctacgaa agcgttcgtc
    59821 cccggcagcg ccatcgaaga cagggtgaag agcgcaagaa aggcggtata gatgggcgcc
    59881 gccttcatca gcccgccgta attcgcgatg ctgcgggtat gcgtgcgctc gtagatcagg
    59941 cccacgaaca ggaacaatgc gcccgtcgtt atcccgtggt tgaacatctg caggatgctg
    60001 ccctcgagcc cgcgcagatt cagcgcgaaa atcccgagcg tcacaaatcc catatggctg
    60061 atgctggaat aggccaccag ctttttcagg tcgtcctggg ccaacgccag caagccgcca
    60121 taaacgattg caagagccga aagcaagagc ataagcgttg aataatagag agatgcttcc
    60181 ggcagcatcg gcagcgagaa gcgcaggaag ccgtaagcac ccatcttcag gagcacgccg
    60241 gcgagaatga tgctgccagc cgtcggcgcc tggacatgtg cgtccggcag ccacgtgtgc
    60301 accggcacca ttggcacctt gacagcgaaa gccaccagga aagcgaagaa tagccaagac
    60361 tggacgccga agggcagatc ctgcgccgtc agggcgagta tgtcgaaggt ctcgcccccc
    60421 tggaaataga gcacgatgac gccgatcagg aagaggatgc tgccggccag cgtatagagg
    60481 aagaacttga acgcagcata gacccggcct tcgccgcccc agacgccgat gatcagatac
    60541 atgggaatca gcatcgcctc ccagaagacg tagaacagga acaaatcgag cgcgcaaaag
    60601 acacccagca tcagcgcctg catgaccagc aaactgacca tgaactcctt caccttgcgg
    60661 tcgatcgcca cccaggaagc gagcacggag atcaagccca acagcgccgt caggaacagg
    60721 aagagcgcgc tgatgccgtc gacgccgagc gcataagcga tcccgagcgc ggccacccag
    60781 ggacggctct cgacgaactg catttcgtgg gtcgtcgtgt cgaagccggc cagcatcacg
    60841 atgcagagag cgagatcgac aataccgaaa ccgagcgccg tccaccgtac tgcatcgtca
    60901 ctgcgcatga acaccagaac tgccgccccg gcgacgggca cgaagacgat gaggctcagc
    60961 aatgggatcg acatcgtgcc cctacctcca caccaccgcg aagacgagga tagccgcgat
    61021 tagaccggcg atcatcgcca gcacgtagtg ggtgacgacg ccggtctgca agcgtcgcag
    61081 tacgccgccg ccgtcaagga tcgatcgggc gacaccattc accacgccat ccacgccatt
    61141 gagatcaagc cgcatccccg tgcgcgccga gccgtgcagg aagggcagca ccgcagtctc
    61201 cgatacgtcg ctgaccgcct tctcataccg cgccaacggc ctttctgcga accacatgaa
    61261 ggcgcgggcg cccttgcggt agaaccagtc ggtgtcgagg ctgatcgtgc tctcgggatc
    61321 gagcgcccga aggaagatca caaagcccaa agccgtaaac atcaggatcc cgaggctctc
    61381 gctcacatgg acgccggtat aaggctcgaa atcgacagga tagggaagaa gcgcgtagag
    61441 cggcccgggg aagatgccaa tggcaatgca gagcgccgcc gccacaccca tcgcgaccag
    61501 catgttgccg ggcggctccc gtgcctgcag cccccgatcg gtaccgagaa acatgtaata
    61561 ggggagcttg agcccagtat gcaggaacgt cccggacgac gccatcgtca gcgccaacat
    61621 gaccagcgcg cggtgatcct gcgctgctgc ggctatcacc atcgatttgc tgacaaaacc
    61681 cgagaagaac gggaatgccg agatcgcaag ggccccggcc atatagaacg ctaccgtcag
    61741 cggcattgcc ttgtaaagcc cgccaagctc ggagagcttg cgccggccgg tgacatagat
    61801 caccgccccg gcacccatga acaggagccc cttgtaaagg atgtgcgcga aggcgtgact
    61861 ggtggctccg ttcaccgcca gctcggtgcc gatgccgatg cccgcgacca tgtagcccac
    61921 ctgactgacg atatgatagg caagaaggcg gcggcagtcg ttttccagca ccgcataaat
    61981 gacgccatag agcgccatta ccgtgccgag ccagaccagc agttcgatac ccggaaacgc
    62041 ccgcgccagc acgtagacgg cggttttggt cgtgaaggca ctcatgaaca ccgcgccggt
    62101 gacggtcgcc tccgggtagg catcggtcag ccaggcattg agtgggggca ccgccgcgtt
    62161 gagcaagaat ccggccagaa tgaggtaggc acccgcgtcc aaagcgccct cgaccggacc
    62221 gaagagcagt gagccagcgg ccgccccatg gagcagaatg ccaccgagca ggacgacgcc
    62281 cccagtgacg tggaccatga gataccgaaa agcagcgcgg atcgcctgtc ccgctccttg
    62341 agcgaagacc agatatgccg acgcgaatgc catgccctcc cagaacagat agagggtcag
    62401 atagtcacct gcgaacacca ccccgagcgc actgccgaca tagacgaagg cggctacatg
    62461 ctcgccggcg ccggaaaggt gcaatgcata gaccgtgccg atcagcgcca tgatggtgaa
    62521 gacggtagcg aagacgatgc tcagcttgtc gaccttcgca atcagaattt cctgaccgag
    62581 gaactgcgtc tcgccataac tgccgggctc tatggccatg acggcgacga tcgccagcac
    62641 agggatcaac acgagatagg atttacgcac cagtccggtg aagaacggga tcggcagagc
    62701 gcctagaatg aagatcaggg ccggatggac gaaatcagtc ataataatcc tcgcgccgca
    62761 tcagcccggc gcgatggccg agaaacttgg aaacgaagat gagcagcacg caagagccga
    62821 agccgtacgc cgccgaccag cccggcaggc gctcccacag gtattcggca tggtcgcgag
    62881 aaaccaggaa gtcggcgacg ataatcagaa agagcaccag atagaacagc cgccggcgcg
    62941 gcctcgcata ttgctcgtca ccaaagaaac cgacgacagg cttgatcatt ggatcactcc
    63001 gtccgcgagg gtgaggaaat agtaggggaa gatgcccatc agtactgaca ggatcgcggt
    63061 cgcaaccagc gggatcgcaa caagcgggat ttcgcggacc ggcgcctggc tctctttggt
    63121 ctccgcctcg aaaaaggcgg tgtagctgac cggcagaaaa taggcggcgt tgaggaccga
    63181 actcgcgagc agcacggcca ggaaagccat ctgcccggcc tctaccgagc cctccgccag
    63241 ataccacttg ctgacgaaac ctgccgtcgg cgggatgccg atcatgctca gcgacgcgac
    63301 gaagaatgcc cccatcgtcc agggaagcct gcggccgatg cccgccatgt cgctgatgtt
    63361 gcgttttccg gacgcgcaat agatcgaccc cgcgcagaaa aagagcgtga tctttgagaa
    63421 cgcatgcgcg gcgatgtgga tgatcccgcc gaccatggcc agcggcgata ggagtaccgc
    63481 gcccaacacg atgtaggaga gctggctgac ggtcgaatag gcgagcctcg ccttcaggtc
    63541 gtcgcgcgtc agcgcataga tcgatgccat caggatggtg aacgagacca aataggccgt
    63601 ggcgaccccg aggcccagtt ctccgaccat gctgacgcca aaaacatgaa aaatcacccg
    63661 cagcacgcag aagacgccca ttttgacgac cgccacggca tgcaagagtg cgctgaccgg
    63721 cgtcggcgcc accattgcgg cgggcagcca ggcatgcatc ggcatcaccg ccgccttggc
    63781 gaagccaaac agatagcaga aatagacgac cgcgagcagc gttgccgagg cattggcacc
    63841 ggccagtaac ccgcccgtca cgaagtcgag cgacccggcg atgtgatagg tcagcgccaa
    63901 ggcagcgaga agcacgcttt tcgaagcgcc catcagatag acgagatact tgcggctgcc
    63961 gcgccatcct tcttcgtcct cgtggtggta gacgagcgga taggtgacga ggctcagcac
    64021 ctcgtagaag atgaccagcg tgaacagatt tgcggcgaag gcgccgccca ctgcggccgc
    64081 gaggctggtg gcgaagcagg cgaaaaagcg ggtctgcgcg tgctcgtgca aatgccgcat
    64141 ataaccgatg gaatagaccg cggccacgat ccacagaagc gaagagacag tggcgaaaac
    64201 catgccgagc gcatcggcgc ggaaaccgaa gtcgatcccc ggcaggacct cgaacaggcg
    64261 cagttcgacg gtgccgccgg ccagcaccgt cggcgccatg gagacgacga tcgcaaacat
    64321 ggcgaccgcg gcaatcggcg ataccgcgtc gcggagtttc tcgcgcttgt tgagaaagag
    64381 aatggcaagg gccgccagtc cggcgacggc gacggcaagc agcggccggg tcgagatcac
    64441 cgggtccaag ccgctatcct ttcatgatgg tgacgtcgtc taccttgagg gtggacttgt
    64501 ttctcaccag cgcgaccaat atgccgaggg ccacggcaac ctccgccgcg gtgatcgcga
    64561 tgacgaagat cgcaaagatc tgtccgcgga agtcgtcgta gtactgcccg aaggcgatga
    64621 aattgatgtt gaccgaattg agcagaagct ccagcgacat cagcacaatc agaatattgc
    64681 gcctcagcag gacgcccccg gctccaatca cgaatagggc cactccgagc aggatcgacc
    64741 aagagagcgg gaccatcagc caggctcctt ccgcgccagc acgatggcgc cgacgagagc
    64801 cgccagcagg atgacggagg cgatttcaaa cggcaggaga tagtccgaga agagcgtctt
    64861 gctgagatct ctgatcgcat caccaccgcg ctcggctacg gggggcgatt cgatgaagcg
    64921 atcgctccag agcaccagca cgaccatctc ggtaccgagc agcaggagca gcgcgagcgc
    64981 cggcaggttg ccgccgggca tgaagcgctg cagcaccgct tcgcgcacgt cgaccatcat
    65041 aatcacgaat aggaaaagga ccatgatcgc gccgacatag acgaaaatct ggatgacagc
    65101 gagcagcggt gcaccgagca taacgaaaat tgcggaaatc tgcaggaagc acgccatcaa
    65161 cgccaatgcg ctgtgaaccg gattgcgcgc caggaccagc gtcagggccg tgaccacgga
    65221 caccgtagcg aacagaagaa agaacccctg atgcatcgac gccgaccttt cgcccacgaa
    65281 ctctcggcgc aggacggccg gagtcgagat agcgccgcac tcgcaaattg tgccctagta
    65341 tcggtttttt cacaagatta ttgtcgctcg gcggggatca gtggtcagag cagcagggga
    65401 gcactgccgc gaaaggtctc gccgggatcc caatctcgct gctacatcga tgacatcaca
    65461 gcctatccgc aggcggcact tgaggcatcg gcgtttgcct taacactgcc gctccgggtc
    65521 aatcgcggag tatccgtatg aaagacatgt gactcggcca cagagccggg tctgttttct
    65581 ggatgagcag cttaaattgc gaccaacccc gtcagcgacg aacgcgggat cctgtcgcta
    65641 aaccctagta tctccacttc ggagtgcgtt tggcattatg ctgcagctcg gaggctgtgg
    65701 cgaaccggcc gaatagccga cgaagtcgga tctcttcttt gtcacccaat tgatgtagtt
    65761 ggcaaaattc gcggacgttc caaatcttgg taacggtgtg cttcgaaagc ttttcggctt
    65821 cgacatgctc catcttgctc ctcccaggca gtagacggcc agactatgct actaaaggct
    65881 aattaagcaa ggaagaatat aagtattact tattgtggca ctatcggatt gccacgctgt
    65941 tttgcctatc tttccactat gctgactcta agaaagaatg gttgacctgt cccgaccaat
    66001 cccgcgtccg gccaaggacg cgaacttctg cgaccgccta gccggcgggc gcattttcat
    66061 gagaccaagc ttgaggtgtt cgataggagc cggaaagatc cagccaaagc agccgccacg
    66121 acgggaagtt gccccaaagc agaccattca gatcgccccc gcgatctgtt gacgcaaccg
    66181 cgcgctctcg gaagtcagcc ttcgtcgcat tgagcagtct cgaacgggag atccgtgttt
    66241 cgcggacagg ccgctaaatc tggcgtcgga tcggctcaac gagatcctgt gcaagcgtga
    66301 gcagcgccat gtcggcgcgc aactgacgtt ttcgttcgag cgccagcgga tcaggcttga
    66361 ggagaccgag gtgccgtgcg gtttggctgg tcgctatgcc gagacctatg cctatgccga
    66421 tggtcgcttt gatgtgcgct ggaaggggta ttgggtgttc gataaggacc agcgggtgac
    66481 gcatgcggcg accaccgaga acaagcggct ttccgatgtg ctggtctaca tcaaggaacg
    66541 ccaggacgag cggccggcgc cgaaggtgaa gaccaacagc gagaagattg gctacaaacc
    66601 gcggggcagc aagccgggca agcggacgaa tttcatgaac gatccggcgg gcgacggcag
    66661 acaggccaat ccctctgtcg ggaacgccgc cgcttcaaga atactgtcct ccaatgccgt
    66721 tcttaagtaa gagaaaacgt ccgtcgcgcc gacgtgcatc agaatacctg tatcaacggc
    66781 tctcacgatg gcctcgccat cgatgaaccc gaagatcttt tccgttccgc tatccacggt
    66841 cgatacgcaa aactcggcga cccggaggga aacactctca atgatgttcc ttaaacctgc
    66901 caggaagacg cagcactcgg caatgtgctc gtacacgagc gctccttatg gcctgaaatt
    66961 gtaagctgac agccttggtt taccggcagg cattattcgg cggatgtttc tttgagcacg
    67021 tcttggattg cgctgcccac cgcgcggata tcatcttccg tccggccgtg gggcaaagcc
    67081 gcaaccctgc cctcccccgt gcagaaccgc tacacactct tgccggaatt gcccaaggca
    67141 tcgcgcgggc gtgctacgtc gttcacgcct tcggcgtcgg gcgcctggcc atagctcatg
    67201 cgtcgcatct gggcgattac gcgctccatc tcgtcgtcgg gcagcacggg cggctcgcca
    67261 agggtgaggg cctggacata gatccgcgac agtgtctcga cttcgatcgc aagccacagg
    67321 gcctgttcca gcgtcttgcc gagagagatc tgtccgtgtt gaccgagcag gcaagccagg
    67381 cggcccttga gcgcgacaag cgcgttgtcg gagagcgcct gggtgccgaa ggtggcgtat
    67441 tcggcgcagc gtatcgtcgt gccgccggca attcccgtca tgtagtgaaa gctcgggatg
    67501 gtcttgtggt ggcacgcaag cgtcgtcgca tagatcgaat ggcaatgcag gaccacgtct
    67561 atatcggtgc gcgcgcgcag aatgtcgcga tggaagcgcc attccgatga cggccgatgg
    67621 cccacatagg tgccgtcgaa ggccatctcc accaggtctt ccggttgcat cgtctcatag
    67681 ggcatggatg agggcgtgat gaggaagccg tcatcggtcc ggagcgagag attgccggcc
    67741 gtaccctggt tgatgccact cgaattcatc cgccggcaga tgtccaccat ctctcgccga
    67801 agtgccagct tgtccgtttc agccatgtag atttcctttc atgttccgga attggtctct
    67861 gttgccgttg tccgggcaac cgcgcgccag tcggcggcgt agcgtaaaag ttcgggttcg
    67921 agccttccga aacgggtcgg ttcactcagt gtcagcggcg ccggcccttt gcgcgtctcg
    67981 tggccggcga gcagcgccgc accggcggca acgccgtaag catcgaggtt gaagcacacc
    68041 ttgcggtcag gcagcagtgc cgccacgacg tccgcataga gtggatcgcg caggaagctg
    68101 ccgtcgagca cgacgaggcg atctgcagaa agcgtctcga tgcattccac cgttagcagg
    68161 gcgcaataaa gaagtgccag ggtcttgcgc tccatcgccg acttgggttc cggcccgagg
    68221 atgcgcccac ttccggcgct gccgggaaaa aggccgtcgt cgtcgccgaa agagggagca
    68281 gcgatcgtcc gctgcgcaag gagacgcaca aggacctcgg gaggggcgtt gtctgtcggc
    68341 gggtcgaccc cggcgatatg ggagaattcc cggccgccca tcgtcagaat accgccgagg
    68401 cgatttccga agaggtcgct gttcagggtc atgccgcgat gctcgtcgag gcggtcgatc
    68461 ggcgtcgacc gggaaaatcc gacgatccag gttcccgtcg agatgaccgt gaaatcctgc
    68521 aggccggcgg cgtgataacg ataatgattg aggctgctgt catggcctcc cgccaggacg
    68581 cgcatttctg ctggaagccc gtaccgcttg acgagttccg gccggatcgg cccaagcgtc
    68641 tgccaggctt tcgcgaaggg cggcatcaac cgctcccagc cgcgggcccc aacaatgggc
    68701 gcccaacgcc tttccgcaac attccagaga tgcgattggg cgccgaggaa gctcgcctcc
    68761 gacgcagcaa taccggaaag ccgccaggcc caatattgcg gtaagccgag aaaccagcgg
    68821 gcttttccga aagcatccgg ctgccgcgct tccatccagt agagctgacg ggcctgatgc
    68881 gtcgctccat gcatggtcgc actgccgcga tcgagaaagg agccggcaag cggggtatag
    68941 ccatcgagga tatcgggcgg caaagactgc tcgtagtcga tcatcggaag cgtggcgcca
    69001 tcgccggcat ccggatccgt gcccgtcaga acgccgcccg agccgtgtcc tgcagtaaca
    69061 atggcgctga gatcgtggcg cctcgacaaa gccgccagag tttcgaaaac ccattggctc
    69121 agggccgtaa cgtcatggtg gcgccagggc ggcccgggga gaacgggatt ggggacgctc
    69181 agcgtctcga cggccgcgcc gtcggctgtg aacgcgctca gcttgacatt cgtcttgccg
    69241 acatcgagga cggcgaccgc agccgctccg ctgccactat cgttcatcgc atccacgtcc
    69301 tcttttccct gcccgcccgg cgccgcaacc tcctcaaatc aggccgtatt gcgtagcctt
    69361 gttgcgcagg aacggcaggc cgttgcccat cacctcttcc tcgtccttcg cgacggggcg
    69421 ccagacggcg agaccatagg cgacttccgg cggcatgttg atgaagcttt ccatagcaag
    69481 gccgcccttg aagccgatcg ccgcaagggt cgaaaaaatc tcgtcccagc cgcaggtgcc
    69541 gtagcccggc gtgccgcggt cgctttcgga aagatggatg tatttcagat gttcgcgggc
    69601 atcgaggatg cccttgccga tgcctttttc ctcaatgttc atgtgatatg tgtcgaggtg
    69661 cacgaacacg ttatcggctc caacccgctc tatcatctta accgcctgcc agccggtatt
    69721 gatcaggtgg ttctcgtaac gattgacggc ttcgacacca agctcgatgc cgcgtgactt
    69781 ggcgtgtttg gccgcggcct gcagcacgcg ggcgatgttg tcgtattcct cgaccgtcgg
    69841 cggcacgccc gtgcgctcgc cgataccgcc atagatcacg ccggacagcg cttccccacc
    69901 gagatccgcc gtcttgtcga tcgcgatctt cagatggtcg atcgccgcgt cgggacgcac
    69961 cgaggcccag gccggttccg gcaggcccag cgagcagacc gcgcgcagac gatgcttctc
    70021 cagcagggca cgggtatgtt ccgtatcgac ggcaggcgga ttgagcatgg gaatttcgat
    70081 gaaatcgacc ttgtatttga cagcggccac taccgccctc tcagctccgg ggcggtccca
    70141 gttcattgtc cacatgctcg tatggacgcc aaaaccctgc atggtcatga tcctcttctg
    70201 acaattgaaa atttgatctt ggaagcgacc caacgcagga tcatcacgcc gacaagaagt
    70261 atcccccaca cggcagtcgc gagatgctgg ttggctccga tgagattgag ccctgacgag
    70321 agaagctgca gcaccaccag cgccacgaag acggggatga cccggccgaa tccgccgaac
    70381 ggattgacgc cgccgagaaa gcacgcaagc acggtgatca gcagatagga ctctccatgg
    70441 ccgacgcgaa ctgaattgaa ccgcgccagc atgatgatgc cggcgatcgc gcacattatg
    70501 ccggagaggg tgtagacgag cacgatcgcc ttgcgcgtat tgatacccga atagcgcgtc
    70561 gcctcgagat tcgagccgat catataggtg ttgaagccga gcttggtgcg gcccagaagc
    70621 aggtgccagg cgagcacgca aacgataaag acgatgagcg gcacggggat tccggcgacc
    70681 gagccatgac cgatcactcc cacgaaagac gggaacccgg agatgtcgcc gccccgcgtc
    70741 aggaattcgc caagtccgcg caggaaaatc atcatcgaca gggagacgag gatcggatgc
    70801 gcgcgcgtga aggctatcac caggcccatg acgacgccgc ttgctgcacc gaccatcacg
    70861 gcaagaagtg agccgacgag aaagatgccg aagccggcgt cgacgccgcc gttcgccttc
    70921 aggacccagg caagggtcag accggccaga ttagccgtaa atgtaattgc gagatttagg
    70981 ccgccggtca ggatcggcag cagcatggca agtgtcagga ggccgagctc cggcagttgg
    71041 aaggcgacgg agccgaaggt cgcggagctc aggaattgcg gagaggcaaa tccaaaaacg
    71101 acgaagacag cgacgaaggc aagtcccggg cctgccattt ccggtccaag cgtggccttg
    71161 atcctttcga aaacagcggt catcgtcgcg tccccttcca accggcaaaa ggcagcaggc
    71221 gctcgagccg cgtgttcgac agcgtgatgg cgatcaggat gatggcgccg ataatcatct
    71281 tgaaggcgaa gggcgacaca cccatcaggt tgagaccgtt ctgggtgatc gagatcaaga
    71341 gtacgccgag cacgcagccg agcacggtgc ccttgccgcc gccgaggcgc gcgccgccaa
    71401 gcacgactgc tgcaagcacg tcgagctcgc ggccataaag cgcgttcggc acgacttcct
    71461 gcgcataatg cgcctggacg aggccaccga tgcccgccat cagtcctaac cagccgaatg
    71521 caatgaattg catggcgccg atgttgatgc cgaagcgccg ggcgccttcc ggattgtcgc
    71581 caaaagcaaa gagctggcgg ccgatcgtgg tgcgcgtgat cagggtccat gtcgcgacga
    71641 cgcagatgat catgacgaga accggaagcg tgatttcgat ccaggtcccg tcgggcattt
    71701 cgcgctcgaa gagtatcacg cgatcggtca gccaatcggg caagtcgtag atcgacacgc
    71761 cgcgcgtaaa gaacatcagc aatccgaaat agatgttgaa ggtggcgatc gtggcgacga
    71821 tcgaaatgat ccggaagcgg tgtatcagga gagcgttgac gcagccaagc agcacaccca
    71881 gcgaagcggc tatcacaaag ccggagagcc aaccgccgcc gccgatccaa cccagcgcga
    71941 tcgccgtgcc gtattggacg acggaagcgg caactgcaaa ggagatgtcg atgccgcctg
    72001 cgatcagcac cacgagcaga ccgactgcga aaatgatgtt gacggagctg atattcagga
    72061 gatcgaaggc gttgccgagc gacaagaaat tcgcggtcgc gaaagacagt acggcactga
    72121 tgacgacgat cacccccaac agcgaaaatt cggtggcatg cgtgcggatc aggctatgca
    72181 tagacggccg cctctatctc ttccaaccgc gtctggtggg gatcatagat gccgacgatg
    72241 cggccctggg ccatgtgcag cacccggtcg gcattgaagt agacttccgg cacttcgtcc
    72301 gagatcagaa taatcgcaag cccgctctcg gcgagcttgg cgacgatgtc gaagataccg
    72361 gcacgcgccc cgacatcgac cccgaccgtg ggggagtcga ggatcaaaag cttgggatcg
    72421 gtggccagcc atttggcgat cgccacccgc tgctggttgc cgccggaaag cgtcgatatc
    72481 gcgtcggcct gatggccgat cttgacgccg agatcggcga tccagcgggc gacgaggctg
    72541 cgtttacggt catcggcgag aaggccgccg gagagaatct tgtgaagcga tgcgatcacg
    72601 agattgtcgg cgatcgactg cggctgaatg agcccgagcg ataatcggtc ctccgacaga
    72661 taggcgacgc cggccttgat cgcatcgcgg ttcgaagcga agcgagcctc ccggccatcg
    72721 atgctgaacg tcccagatgt aggcttcagc atgccgaaaa gcgcgagcgc caattcggtc
    72781 cgcccggccc ccaggagacc ggttatcccc accgtctcac cacggcggac ggtcagtgaa
    72841 acatcttcga actggcccgg actgccaaga ccgcgaacgt cgagcacgac cggctggtcg
    72901 tccttcgcgc gtgcgcgcac gtgctgatcg aaggtcttgc cggtcatgag ttcagtgatt
    72961 ttcgactgcg tcatgccgtc ggcgggatac acgccgacaa gcgcaccgtc gcgcagaacg
    73021 gtgatccggc tcgaaatctc aagaacctcc gccagacgat ggctgacgaa gacaaccgca
    73081 acgccggagg ccgacaggcc gcgaacgatc tcgaggagat aatccgtctc cgactgcgtc
    73141 agcgacgccg tcggctcatc catgaagaca actttcgcct caccgacgag cgctcgggcg
    73201 atcgccacga tctgacgctg ggcgatcgca tattccttga gcggcagatc cacatcgagc
    73261 gtgatgccga gccggctcag cgcttcgatc gcaatctggc gcatgcggct gtaatcgacc
    73321 agccgcggac ggccaaggac ttcgtggaac gctatgttct ccgcgacgct catttccggg
    73381 aaaagtgcaa ggtcctgcca gatgacctga atgccgcgct cttgcgcggt gaccggcgac
    73441 atatgcggat agacatcacc gtcatattcg atgatcgccc cttccgctgg ccgatagacg
    73501 cccgtgatca ccttgatcag cgtgctcttg ccggagccgt tctcaccggc gaggcaatgc
    73561 acctcgcctg gtcggacctc gaaggtcaca ttcttaagcg ccttgacgcc gccgaaggtc
    73621 atattgatgt ttcggagaga cagaagcggc tggtccgtac gtgccgcgct tgccgactga
    73681 tgcatgctac cgtggcccat cgatggtgtt tcctggggat ctgccaggcc ggccgaagcc
    73741 ggcccagcag ccgggagaac ccgttggtgg ggcgggaacc acttggcccc cgcccgactt
    73801 ctgtccgttc agagacccat tgcggcgagg tcggcgaccg tctccttgtt gatcggcacg
    73861 agctggtcga cgatgatgtt gcggttttcg aagtcggggt ggatcacgcc gagaccttcg
    73921 atttcgtcac catccttgat ctcctcgccc ttcatgagct tgtcggcgag cgtcacgaag
    73981 acttcgccgg cctgcttggg attccacata aagccgccgg aaatcgcatc ggccttgatg
    74041 agcttctggc cctgcccggg cgagaagggc ccgaggacga agatttcacc agtcttacgg
    74101 cgctcttcaa tagcgcggcc ggcgccgatc gggccctggc ttccgaaggc gagaaagccc
    74161 ttgaggttcg gatgagcgga gatcaggtcg agcgccgtcg accgactctt gtcggcatcc
    74221 tctgcgacgc cgtagcgatc gccgacgagt gtcatttcgg agtggttttt cttgatgtat
    74281 tcgatcgccg catcggccca ggcattgtgg agcggcaccg tcagcgaccc gacgaaaacc
    74341 gcatactcgc ccttgccgcc cattttctcc gcaagcagtt tggcatgcgc ctcgccgaag
    74401 ccggtcgctg atgcaagttc gaagtcccaa tccgcgccct tctggcttgg cgactcatgg
    74461 gtgatgacga taatgccctt ctcctttgcc ttggtaagaa ccggctctag caccttcgcg
    74521 tcgttgggga cgacgccgat gaccttgacg ttctgggcga tcaggtcttc gatcgcgcga
    74581 acctgcagtg ccgggtcggc gctggtcggc ccgaccatga aagcgtcgac accgagtttt
    74641 tcgccacgct ccttgattcc cgcctccatt gcgttgaacc acggtatgcc gccgatcttg
    74701 acgacgatgc cgaccttgcc ggaatcctgc gccgcggctg tataggcacc ggcaagcgaa
    74761 agcgatgccg ccagagcggc agcaagaatt ttcctgatca tatctctcct ccacatgttc
    74821 ccgaagggaa cgctcccggc gcttccacgc cgcctccagc ttcatcttct tggacggaaa
    74881 ggaatatccc cgccgctgac ggccgcctcc tcagacggca ccaacgactc gcacaatcga
    74941 tatctctttt ttttgcacaa tcgatggtgc aatgactatc atgcagactt agtctttcgt
    75001 caagccgaaa tcggcactaa gggatcgcag gaggctcgca tgacgaacgg tggcaggaaa
    75061 aaggcgacaa tctatgatct ctcggtgcta tccgggagtt cgccttcgac ggtaagtgcg
    75121 gtactgaacg gcacgtggcg caagcggcgg ataagggaaa gcaccgcaga gctcatccgg
    75181 agccttgccg aaacgcatca gtacactgca aatcgtcagg cgcggggctt gcgcagctcc
    75241 cgttccggcc tggtagggct gctcctgccc gttcacgaca accgctattt ttcttcgctt
    75301 gcccagacct tcgaagcgca tgtgcgaagc aagggtcagt gtccaattgt cgtcagcgcc
    75361 agccgcgacc cggaagagga acgcaggacg gccgaaacgc tgatctccta ttccatcgac
    75421 gaattgttca tatgcggcgc gacggatccc gacggcgttc acgaggtctg cgaagcggca
    75481 gggctgaagc acatcaacat cgatctgccg gggacgaagg tcccatccgt catcagcgac
    75541 aatttcgaag gcggccgtat tctgaccgaa gcaatcatcc gccacttccc tgccgaccgg
    75601 ccgctcgcgc ccgaggatct ctatttgttc ggtggtcgtg atgatcatgc cacccgcgag
    75661 cgcatccgcg gctttcgtgc cgcaaagaag gagttgctcg ggggcgatcc ggatgaatgc
    75721 gtatggccca ccggttatgc ggcagacaat gcgcggaagg ccttcgatgc cttttacgaa
    75781 cagcggggga aacttccgcg cgggttcttc gtcaattcct cgatcaatct agagggactg
    75841 ctgcgtttca tggccgagca tccgctcgag aatttcaagg atctcgtcgt cggctgctac
    75901 gactacgatc cattcgcatc cttcctcccc ttccccgtca tcatgataag acaagatgtc
    75961 gagggaatga tcgccagggc ctttgaggtg atcgaggagc cgcgggcgtc ggtccagatt
    76021 catttggtga aaccgaggct cgtgcccccg agaacggcgc tgaccggccc cctcgacgcg
    76081 ctaatcgaca gcgacatgcc gcggtaaagc cggacggcga ccgcccctcg ccacctacca
    76141 ggttccgacg gtcagactgc ggtgcggctg ccgggaaaca gcagttcgat gaagcttgca
    76201 gccgtcggct gaggctcatg atttgccagg cccggacgct cgttggcctc aatgaagacg
    76261 tagtcggcca gcgcgggatc gcgcaccatc aggtcgatgc cgacgaccgg gatgttgata
    76321 gcgcgcgctg cacggcaggc ggcatcgaca agatcaggat gcactgtatc cgtcacgtca
    76381 tggatcgagc cgccggtatg gagattggca gccttgcgca cggtgatctc gatgccctca
    76441 tccagcaccg tgtcgagatc gatgccctgt tccgcgaggc agcggtccgt ttccgcatcg
    76501 agcggaatcc ggctctctcc accggttgcc gcctcgcggc gccgcgactg tttctcgata
    76561 agtgaggcga tcctgctgcg gccgtcgccg ataatgcgtg gcggcaaacg aatagcggcg
    76621 gcaacaagcg tatagtctat gatgacgagg cgcaggtcct gcccctcgaa acaggcttcc
    76681 agcaacaccc ggtcgcagac ctgacgagcc gaggcgatcg cctcctccag cgcgtccgcc
    76741 gccgtgatgc ccacagagat gccccggccc tgctcaccgc gcgccggctt gatcaccagc
    76801 ttgccgtgct tttcgagaaa ggcctgaatg gcttggtggt cctcgcccac ctccatctgg
    76861 tccggaacga caagtcccgc cgcggaaacc atgcggcgcg ttatcgcctt gtcgtcgcag
    76921 atcgacatcg caacgccgga tgtcagttcg gaaaggctct cgcggcaatg gatcgagcgg
    76981 ccgccatggg agaggcggaa aaagccgcct tccgcatcgg taatatcgac gtggatcccg
    77041 cgccttgtcg cttcatccac gatcagccgc gcatagggat tgagcgcatc gtaggattga
    77101 tgcggcatgg cgaagaactt ctcgttgatg gcattcttcc gcttgatggc gaaaagcggc
    77161 atgcgccgga aattcaactt ctcgtagagc ccgatcgcca gcgtattgtc gtgcatgacg
    77221 gacaggtcga cataggagag gccgcgtgct tgaaaatgct cggcaagttt gcggaccaga
    77281 tgctcgccga tgccgggctg acgcgcctgc ggatgcaccg ccagacacca cagcgaagca
    77341 ccgcgatccg gatcgttgaa cagcctctgg tggtcgattc ccgtgaccgt gccgacgatt
    77401 tcgccgctgg cgtcgtcctg cgccacgaaa taggtcagcg accgttcgtc cctttcggac
    77461 gagaagaaat cagatcggat ctgaaccatg ccgcaggccg catagaccct gttaatgcct
    77521 tcgccgtcgg cttcggacga gagcctgcga atcgtgatcc cccgtgtgcg gcgcgtgttc
    77581 gcacgatagg tccacaggtc gagcctgtaa gtgtgcgacg ggtcgaggaa aatctcctgc
    77641 ggagctcgcg acagaagcac atgcggatcc cgaacataaa aggctatatc gcggctggaa
    77701 ggcgcctcct cgcgcagttc ggacaagagc ttatcgtcgt cggaaaaagt ctgcgcaaac
    77761 agcagcctgc cccaaccgca atccagaacg acgtcctgct ttgtcgcttc cgaggcgcgc
    77821 ggcccatccg gttcgcgccc cggttgggca tgcttgcgca gccggttcaa acggtgcgtg
    77881 acggctttgg tgcccttgct gcgctgacgc ggcgatgcga tctctcgcgt cttcttcatg
    77941 ctacaccccc tgcgcttcga gccacatttc gagcagtccc acctgccaca gctcggagcc
    78001 gcgcagcggt gtgatgtgat cagacggctg ctcgaacagg cggtcgagat aggtgtcgcg
    78061 gaagaggccc cgctcacgcg ccctctgcga gttcagcgta tcgcggatca ggtcgagata
    78121 tggacccgca atgtatttga gctgcggcac cggaaaatag cccttcttgc ggtcgatcac
    78181 ctcgctcgga acgatcttgc gggccacgtc cttcaggatg cccttgccac cgtcgcgcag
    78241 cttctcctcc ggcggaatac gcgcggcgag ctcgaccagc tcgtgatcga ggaaaggcac
    78301 ccgcgcttct aggccccagg ccatcgtcat gttgtcgacg cgctttacgg gatcgtcgac
    78361 gagcatgaca ttgctgtcga gccggagcgc ctgatcgacc ggcgtgtcgg cgccgtcgcg
    78421 cagcagatgc tcgttgagca acgcgccgct cacatcgtga tcggcaagcc acaggtccga
    78481 cagctgtgtg gccaataccg catgggaacg gtcgcgaaac gccttgccgt aatctccaac
    78541 gacgtcgttc gagttcatca gtggcggata ccagtgatag ccgccgaaaa cctcgtccgc
    78601 tccctggccg gactgcacca ccttcacgtg tttggagacc tccttcgaca gcagatagaa
    78661 gccgacattg tcgtaggaaa ccataggctc agacatagcg gttatggtgc cgggcaaggc
    78721 gcccatcaaa tcggcggacg gaacgaagat cttgcggtgg tccgtaccga aatgctcggc
    78781 aatcaggtcc gaatagacga actcgtcgcc cttttcgccg ttagcctctt cgaagccgac
    78841 ggagaagctc atcaggccgc gctgacccgc ttcagcaaga agtccgacaa tcagactgga
    78901 atcaaccccg ccggaaagca gcaccccgac cggcacgtcc gcgatcatgc gccgcttcac
    78961 ggcaatgcgc agcgcatcca gaagccgctc ctgccattcc tcacgggtta tggctgcgtc
    79021 gcccgcctgc cggcgatagg gcggatccca ataacgccgg tccttgaagc tgccgccgcg
    79081 ttcataaacg cgaagggtcg ccggaggaag cttgcggacg ccgttcagga tcgtacgggg
    79141 gggcggcacc accgcgtgaa aggtcatgta gttgtggagc gccgccacat cgatcgaggt
    79201 gtcgacacca cccgccttga cgagtgcagg caaggaggaa gcaaagcgca gcgcaccctc
    79261 gacttcggcg atatagagcg gcttgatgcc gaaacggtcg cgcgccatga caacgcggcc
    79321 gctgtcacgc tcgtgaatga cgaaggcaaa catgccgtgg aaccgggaga cgcattcctc
    79381 gccccaggca tgccatgcct tcaggatgac ctcggtatcg ccggaggaaa agaacttgta
    79441 gcctttctcc tcgagctccg acctcagctc gcggaaattg tagatgcaac cgttgaagac
    79501 gagcgatagg ccgagttcgg ggtcgatcat cggctgctgc gacttgtcgg agaggtcgag
    79561 gatgcgcaaa cgccgatgtc ccagcccgac atttcctcgc actacgacgc ccgacccgtc
    79621 cggtccgcgc ggcgccagga cgtccgacat gatcgatact gccttaaccg acggcgaacc
    79681 gccatcgaac ctgatttctc cacaaattcc acacataaac cgggtcgaaa cctccattgt
    79741 tggtacgaga tgtaacgtcg ggagaaaacg tcttccgtcc cgacgtcgtg atgaaaactc
    79801 aatgcccgac tacgtcgacg gttccgcgac aggcgtcacc cggtcgcggc ttcgcgctcg
    79861 agcatgtagc tctcggcaaa ggccatatgc tcggtggcga tcgcacgggc atcgtccgac
    79921 cgtccgtcct gcagggcggc catgagccgg tactggaagg acagcccctt ctcgcgcgaa
    79981 agcggtgtcg ggtcggcata gatcgagcgc gcggccggga gctcgcgcaa caggttgtgc
    80041 atgagcccgc agacaaagcc gagaagcggg ttcggacaga gctgcgccag catcgaatga
    80101 aaatcgagtt cggcgatgcg ctgtcgatat tgctcttcca gatcggcggg cggatgatcg
    80161 taaatgcgga tcgtgttttc gagcgcggcc agttcttctc gcctcatcct gccggccaac
    80221 aagccggcaa cctccggctc cagcaccttg cggatcgcgt atatgtcgcg aatgctcggc
    80281 tgatcgaaga agaaatgggt cgacaggagc tccatggcat ggcgcgccga gggctgggcc
    80341 acaaaggcgc cgccacccgg gccgctgcgc gtgaagacga ggccctgggt ctcgagggct
    80401 ttcatcgcct cgcgcacagt gcccttggcc gccttgaagg tgtcgatcag atcccgctcc
    80461 tgcggcaggc gatcgcctgg cgccagacct tccgagcgga tgtaatcctt gatgcgatcg
    80521 gcaatcgcct ccggcctgcg cttcgtacgc tcggccggaa caaagagccg ctggccgtct
    80581 ccacctgttt ccttcttcat ttcgataacg actgtcatga accgtcactc tttcctgatg
    80641 cggggcgcgc tggcgactag ccgtcgtgta taggcgtgct ccgggtcggt aaaaaggcgg
    80701 gcggcgggtg cggtctcgac cacctcgccg aaatacatca ccgccacccg gtcggagatc
    80761 gcctcgacca ccgccagatc atggctgatg aacaggtagg aaaggccgaa gcggttcttc
    80821 agatcgcgca gcagaagcag gacctgcgcc tggatggata cgtcgagcgc gctgaccggt
    80881 tcgtcgagca cgatgatttc ggcctccgtc gcgagcgccc gtgcgattgc gatccgctgc
    80941 gcctgcccgc cggaaaattc atgcgggtag cgcgacaggg tatcctccgg catctgcacc
    81001 gcgtgaagca gttcctgcat ccgcgcgcgg cggcgcggcg cttcgtaacc gcacaagcgc
    81061 gtcagcggcg tatcgaggat ctcgcggatc gtcttgcgcg ggttgagcga cgcgacggga
    81121 tcctggaaga catactggat cgtcctgccg aaagcccgtg gaccggatcg acgcaaggcc
    81181 ccggcgtccc ggccgccgat cagcatgctt ccggatgtgg gctcctccag gccgacgagc
    81241 atgcgggcaa gcgtgctctt gccggacccg ctttcaccga cgatggcaag cgtctcaccc
    81301 cgcgcgacat gcagcgacac cgcctttacg gcctctatct catgcctggc ctttccgaag
    81361 agattgcgcc cgccgccgaa ggtcttggaa aggtcgcgga cctggatggc agcacccgtc
    81421 atcacgccac ctccttcttg tcttcggcaa aaagcgttgc aacacgatct aggaagcgcg
    81481 cgcccgtccc gagctcgggc acgcaggcga tcagacgctt cgtataggca tgctgcggat
    81541 cggcgagaac ttgccgggtt tcccccgttt cgacaatttc gccatccttc atgacggcca
    81601 cgcgatcgca aaactcggag acgatcccga aatcgtgggt gatgaagaga agcgccatgc
    81661 cccgctctct ctgaagatcg cgcaggagct ccagaatgcg ggcctgcacg gtcacgtcca
    81721 gcgcagtcgt cggctcatcc gctatgataa tttccggatc gttggcgagc gccatcgcaa
    81781 ttccgacacg ttgacgctgt ccgccggaga gctggtgggg atagtggacc gaccgcgccc
    81841 gcgcgtccgg aatgcccacc ttttccagca gttcaattgc ctttttgcgg caatcggccg
    81901 cgctgatcga ctgatgcgcg gctatcgatt cctccacctg ccgcccgatc gcaaccatcg
    81961 gatgcaatgt cgtgagcggg tcctggaaca cataggcgac acggctgcca cgctttgcga
    82021 tcagcctggt ctcgggcatg gaaagaacat cctcgttccc aacgtagacg gcgccgttgc
    82081 ggatcacacc tggcggcgag gcgacgagcc ccatgacgga caaggcggtt acgcttttgc
    82141 ccgagccgct ctcgccgata agtccgaggc atttgcccgg cttcacgtgc agcgagacgc
    82201 ctcgaaccgc cggtatgaac tcccctccct gccgaaaccc tgtttccagt ttctcgatta
    82261 cgagcacggc atcgtcagcc gtgcttgccg gcgccgtgcg atcgcgcgcc acttcggtga
    82321 ccggccccgg gcgcgcgagt gcgcccgagc gaaggcgcgg gtccagcaca tcgcgaattc
    82381 cgtcgccgag aacgttcagg ctgatgacga tcaggaagat catgacgccc ggcacgatcg
    82441 aaacatgcgg cgcagtaaag atttgcgcgc gcccctcacc cagcatggag ccgagatcgg
    82501 cctggggcgg ctgcgcaccg aggccgagga agctgagacc ggccgtctcg aggatcatcc
    82561 agcccgccgt cgtcgacatc gtgatgacga tgacaggcat cacattcggc agaacttcgg
    82621 tgagaatgat cgacagatgt cccttgccgg agagccgtgc cgcgtcgacg aattcgcgat
    82681 gggcgtagcc gagcgtcacg ccgcgcacat tgcgggcaaa gaacgggatg tttacgaggg
    82741 cgatcgcata aagcgcgttc atcagccccg gcccgagggc ggcgacgatc gccaacgcca
    82801 gcaggatgta ggggaaggcc atcagcatgt cgatgccgcg catcatcgcg ttgtcgatgc
    82861 gcccaccggc atagcccgca acgatgccga tcgccgatcc gatgccggca gcgatgaatg
    82921 tcgcggcgaa accgacggcg accgaaaccc gggtgcccca aagcaggcgg ctcaatatat
    82981 cccggccgag ctgatccgtg ccgaggaggt gtccggcggt cagcactggt ttcagccggt
    83041 cggctggtgc cgtggcattc ggatcgggaa gcggcaggat tggcgcgagg gccgtcagca
    83101 acaggatcgt tccaaggagc acgagtcccg ccgtcgccaa ccgattgttg accaacaggc
    83161 gccacgaggt gatccgtgcc gatccggcct gcggagcggg cgctgcagca agcgtgctca
    83221 tgtacgaatc ctcggatcga gcatggactg aacgacatcg gcgagaagat tgaacagcac
    83281 gtaactggcc gcaacgacga gcacgccgcc ctgcaccagc aggatatcgc gcgccgaaat
    83341 cgccttcacg agcattgcgc cgatgccggg ccactggaac accgtttcga catagacggc
    83401 gccgccgagc acgaaaccgg cctggatgcc tatggccgga atgacgctga caagggccgc
    83461 acgaaaggca tgagcgtaga tcactctacg ctcgggcaag cccttggcgc gggcagtgcg
    83521 cacataatcc tggcgcagga cctcgagcat cgctccacgt gtcagccgcg cgataacgcc
    83581 cgcggcaacc acggcaaggg tggttgccgg caggatcaga tggagcagaa ggtccttcag
    83641 gtcacccccg ccatagaccg cgtacatgcc ggacgccgga aggatgcgcc aatgaacggc
    83701 gaagagatag atcagcagaa ggccgagcca gaaggacggc atggaaatgc ccgccaggac
    83761 gaaaaaggtg atgatgcggt cggcccagcc gaactggcgc accgcggaga tcacacccgc
    83821 aagaaggccg attagcgaac acacgaccag cgatacgccg gcgagtacca gcgttgcctg
    83881 gaaccgctcc agtacctcgt cgagcacggg ccggttcaag gcgaaggaac ggccgaagtc
    83941 gccctgcaac acgttaccca tccagatgac gtattgctgc accagcggct tgtcgagccc
    84001 gaggtcgcgg ttgatgcgct ccacattttc cggcgtcgca tacgagccga gaatggccgt
    84061 cgcggcatcg ccgggaataa gagtcatcac caggaaaacg atgatggaga gcccgaacag
    84121 aacgggcacc acggcaatca gccgcgtcag gacataggac ggcatggtaa ccttccggga
    84181 agatccgtgt tgttgccacc agcagaaacg agcgtgccga cggcaattcc gctgcgcgaa
    84241 ctactctttt gtcacgccat ggagatcgag caggaaggag ggctgcaatt cgaagccctt
    84301 caccgcggcg gttgtcaccg cattctgctt ccagttagcg acgaaaagcc acggcgcgtc
    84361 gtcatgaacg atcgactgaa cctcgccgta gagcttgccg cgctcggcct gatccgtgga
    84421 tttgcgcgcc ttttccagga gctcatcgag cttcggattg gaataatagc cggagttgaa
    84481 ccctcccttg tccggcatcg cgtcagtgcg caacgtcaga taggggacgg tatctggatc
    84541 attcgtcatc cacgccatct cggccatatc cgctttgcct tgaaggccgg ggttgacgcg
    84601 cccgaggaac gtattccact catacgtctc gatcttgacc ttgaagccga cggcctggag
    84661 atcggcctgg atcgcggcgc ccatggtaat cgggtcgagc atgccggaac ctccctccgt
    84721 gacatagaac gtcacttgcg gattttcgac ccctgcctcg gcgagcaggc tcttggcctg
    84781 ttcgggatca taagcatagg gctttaccga gctttccacc caattgaagg ccggagggat
    84841 cggaccggct gccactgtcg ccgtcccctg cagcacgtcg ttggctagcg tttccttgtt
    84901 caccgcataa tttgcagcct ggcgcacgcg cttatcggca aaaggtcctt ccttggtatt
    84961 caggatagcg aaccagacat gcggccctgc ctgctctgca acggcgaaat tggcgtcctg
    85021 cctaaaggtt gcgagattgt ccggcggcac ctccaccatg acgtcgatac cgccggccat
    85081 catctcggcg actcgcgtgt tggcgtcggt gatcggtcgg aagacgaccg cctgaagctt
    85141 tgcggcaccg tcccaatagt ccggattgcg ctcgaccacc acacgctggt tcgacagcca
    85201 ttccacgaac ttgaacgcgc cggtgcccga tgggctgcgg ccatattcct tgccatgttc
    85261 ggagaccgcg gccggagaga cgatcaggcc cgtgggatag gcgaggtttg agaggaacgg
    85321 cgcgaatgct tcgctcagct tgaactcgac cgtgtgctcg tcgaggacat tgaccgaatc
    85381 caccgaggaa aagttgaagg aaagcggaaa tggaccggtg ccgtagaacg gatggtcctt
    85441 cttcaacatg cgatcgaaat tgaacttcac cgcctctgca ttgaaatcgg aaccgtcgtg
    85501 gaatttcacg ccttgcctga gcttgaacgt gtaagtcttc ccgtcctcgg agatttccca
    85561 gctttcggca agcgccggct cgacttccaa tgtgccgtct ttgaaccgga ccaagccgtc
    85621 atagacgttg accagaattc ggaaatcatt cgtcgcggtc actgtatgcg ggtccagaga
    85681 ctgcggctcg gcaatctggc cgacgacgag gacgtcgggc ggagtctgcg ctccggcagt
    85741 ccctgcaaat gcaagagcag ccagaaccat ggcgctccga atcagcctct tcatggggaa
    85801 gatcctttcg atttggcttc agttcgcagc gctatctata actataaata ataaaagcgc
    85861 aataatttat catgataaac ctcgcggtca cgcgcgcgaa tcgtcttggc cgccgcgttc
    85921 acggttcgat cgcgcgattg gcgcaggaag gaaaactgag cggatttccg accgttcccg
    85981 ctcgacctta tgaaaaccgc gcccgcgatt tcagatcaat ccgacgaaga atcattgtga
    86041 tctataaact tggggtgcgc gctttgcgcg tacgcgttaa ttgcgaagcg atgcgaaagg
    86101 gccgcagcaa gcattgccgc ctccgcgcct gcgccttccg cctcgacgtc aagtgcagct
    86161 gaaaacagtt cgccgccgat atccgcacgc ttttcgggga catggtcgta aacggcaccg
    86221 gtcgacggct tgacgaagaa cgtgtcgctg atcgatcgtc gcctgctcga atgtggcgct
    86281 cgagattcga cgtgacgcca tatagagcgt tcctcgcttg tggttcgtga cgacatacac
    86341 gtagcccgcc atgcagaaac gatgttcgtg gctggattct cgggtcaagc ccgaggatga
    86401 cggcgggagg ggtaagcgca caaaaacggt agagcgacgc aggtgagccg agccgtcccg
    86461 tcaggggcag acacacgtcg tgggaaaatt gacgtaacgt gcagttcttg cgatcacagc
    86521 cactaatagg caggccggct tgcacgttcg tcgtaacggc atccggcgtg acactattca
    86581 ccgaatcaga acatctataa tgtccaaagg ctgccacccg aaggacaaca gcagccgaag
    86641 cggccttggc cggcctgctg atctcgggct attcaccagg gttgctcatc gcggtcgcga
    86701 gcctcggcaa cgtgcttgct tcggtcatga attggggact gggccggggc atcgagcatt
    86761 ttcgggacag gcgctggttt ccggtgcgcg acgccgggtt ggagcgtgcg cagcactggt
    86821 atcgccgtta tggaaagtgg tcgctgctcc ttagttgggt gcctgttgtc ggcgacccct
    86881 tgactgtggt ggcgggcata atgaaggagc cgctgttgcc gtttctgttg ctggtggcga
    86941 tcgccaagtc ggcacgtcat ctggtcgtgg gaccggttac cttgaactgg gcatagcgct
    87001 atgttccaag cgatcgccgt cacgcagccg cggccgccat gccgccctca ccgaacatat
    87061 aaaactttcg gaaatgccgg caaatgggcg gcgatccccg cctttgcgcc gatcatgcag
    87121 gttgattcga gccgcttgac agcggcgcag aaagagcgga aaacaccccg catggggttg
    87181 cgatcacccc acgaggcgac agccgaagta tcgcgtccat tttaaccgct cacacggagg
    87241 acgcgtcaca tgtcgtcaca tctcgaaatc gctcccgaga aacttgcccg cctcatcggc
    87301 acgccgaaat gccccgcgct tatcgacgtc cgtgtgggcg aggatttcga cgaggatccg
    87361 cgcctagtcc cgggctcgat ccgtcgcgac taccgcaagg tccaggaatg ggccactgaa
    87421 ctcggcggaa cttcggcggt cgtcgtttgc catcgtggca agaagctgag ctacggcgtt
    87481 gccgcatggc ttcgcaatta tggcattgcc gccgacgtcc tcgaaggggg ggtcgcggcc
    87541 tggaccgaag gcggctatcc gaccgtaccc atctccgcga taccggaacg cgacgcgagc
    87601 ggccgcaccg tctgggtgac gcgagcgcgg ccgaaaatcg accgtatcgc ctgtccctgg
    87661 ctgatccgcc gcttcgtcga tccgctggcc gtcttccttt acgttgcccc gtccgaggtc
    87721 gaggcggttg ccgagcgctt cgcagcgacg cccttcgaca tggatgcgcc gatccgctgg
    87781 agccaccggg gcgagctttg caccttcgac ataatggtcg aggagttcgg cctatcgatc
    87841 gaaccgctgc tgcgactcgc gaccatcgtt cgcggcgcgg atacgtcccg cctcgacctt
    87901 gcgccacaag cgtcggggtt actggcggca tccctcggcc tgtcacgcat gtatgccgac
    87961 gacctcgagc agctcgaggc gggcatggcg ctctacgatg ccttttatcg ctggtgccgg
    88021 gatgctaccg acgaaacgca caactggccg tctccgaaga aggattcgtg atgagcgaga
    88081 tcacaaacag tgccctgccc gatacggctc ggcaagatta tggtcatggc attccattcg
    88141 gcgaggcggt tcgggtctgg gcaaggattg ccgccctcag cttcggtggc ccggccggac
    88201 agatcgcggt aatgcaccgc atcctggtcg atgaaaaacg ctggataggc gagcaccgtt
    88261 ttctgcacgc attgaattac tgcatgctgc tgccggggcc cgaggcgcag cagctcgccg
    88321 tctatatcgg ttggctcctt caccgcaccg caggcggtct cgtcgccggc acgctgttcg
    88381 ttctgccggg tttccttgcc atcctcggct tgagctacat ctacgccgcg tttggcaatg
    88441 tcagcattgt cgaggggctg ttcttcggtc tcaaggctgc agtgctcgcc gtcgtcgtgc
    88501 atgctgtttt ccggatcggc agcagggctc tcaagaacta tctgatggtc ggcatcgccg
    88561 ccgcggcctt catcggcatt ttcttcttcc gcgtgccctt cccgctgatc attctggcag
    88621 ccggcatctg cggatatatc ggcggccgct ccggttcgcc cttatttaga attggcggcg
    88681 ggcacaaagc gggaagcggc gcgatcctcc gagacgaaga ttcgctccta ggagaggaaa
    88741 cgccggccca tgcccgtccc aatctttcct ggtcgctacg catttcggcg gtgttcttcg
    88801 cgatatggct cgtgcccctg atgctgctca cagcctttct cggcatcgac aatgtcttca
    88861 cgcagatcgg cctgttcttc agccagatgg ctgtcgtcac tttcggcgga gcttatgccg
    88921 tccttgccta tgtcgcccag gaggcggtcc agcactacgg ctggctgaag cccggcgaga
    88981 tgctcgacgg cctcggcatg gccgagacga ctccggggcc gctgatcatg gtcgtccagt
    89041 tcgtcggctt catgggggcc tttcgtgatc ctggatcgct gaacccgatg acggcggcga
    89101 cgcttgcggc gatcctgacg acctgggtaa ccttcgttcc ctgcttcctc tggatttttc
    89161 tcggagcccc cttcatcgag cgccttcgta acaatgtggc actgaccggc gcgatgtcgg
    89221 cgatcaccgc cgccgtcgtc ggcgtgatcc tcaatctggc cgtctggttc ggtctgcaca
    89281 cgctgttttc agaggtggtg acctggcgac tcggatggtt tgcactcgat gtccccgatc
    89341 cggcctcact ggtgttgcca tctctggtgc tgacagcggc ggccgcgatc gcaattttcc
    89401 ggtatcaggc ttcgatcatc gcaaccctgc ttgcctgcgc tgtcgccggg ctcgtctggt
    89461 cattgatcgc gggcgcctga ttacacgcct ggatcaaacg gtacgaacac acgaagtctg
    89521 caagattccg catgctcgcc tgccctgacg gcaggccgca cagactttgc tgcctgtttg
    89581 gcgaagatct gctctatcgc gtgagctgca aaatccgaga actggaagcg aaatgcaggc
    89641 gcctgcccga aaagcgttca aaggcatgat caactcggag gtcgcgaact gaagtcccgg
    89701 ctccgcccct acgattccaa cggatagact ccctcttccg gggcgttgga aaagctttgc
    89761 agcgtctgac cgccgtcgat cagccaggcc gctccgttga cgtggcgggc agcgtccgaa
    89821 gccaggaaga gcaccacctc tgcgacatcc gccggctggc cgatccggcg caacgggata
    89881 cggtctgcga aatgctcgac cgcagagcta cccttgtcct cgcccaagcc cggtacgccg
    89941 agcgtggtct cgatgacgcc ggggcaaatg gcgttgacgc gaatgcggta gcgggcaaga
    90001 tcgagtgccg ccaccttggt gagacccacc acgccgtgct tggtggatgc atagccggct
    90061 ccgccggaaa ggacgtccca gccggacatt gatgacgcca tattgatgat cgagcctgat
    90121 ttccgcgcta ccatgttcga tgcagcgaat ttgagcatca ggaacatgct gcgcaggttc
    90181 accttgacga tgtcgtccca tgcgtcgacg tccagcaggt ggacgggagc gacctttccc
    90241 gagatgccgg cattgttgaa cagaatatcc agcttgccgt acacaccgac agcatggtcc
    90301 acggctgctt ttgcggtctc ggtctcagaa agatccccag ggatcgtgct gacccgttct
    90361 cctccgttca gagcctctgc cgccgtctcc agcttcccgg cgtcgatatc ggcaagtacg
    90421 acattggcgc cgcgctcgag gaagagtttc gcggcgcttt ttccaatcac gccggccccg
    90481 ccggtaacga ggacggtttt tcctgaaaag tcagccacgc ggttctcctt cgatggaacg
    90541 tcatagcgct tacgcgtttg cagggttcta ataatcgcgc cacgaataac gcggaacgaa
    90601 gtcgataagg tgctttgccc ggtcgttgga gagtaggcca gcatggcctt cgagcgaagt
    90661 tcggacctgg gttccgggat atcgcgccgc cagcaggtcg gccgtcggtg tctcactgta
    90721 gctgtcgccc gcggaaatga agaaccgctc gtgaccgggc gtctgagcgt tcgccgccag
    90781 caggaacgcc cgggctgcgt cccgggcgtc tatgtaggcc cagagatcga gagcggcctc
    90841 ctccgtcaaa cgccgtttcg ctacctcgaa catgaaactt tcgggtgtct ggatccaggg
    90901 catgcgcagg ctgattgccg atcccccgat ccgccgggtc cacgcatcga ccatttcctc
    90961 gcccagccat ttggtaacgg catagacgtc ctgcggttgc gccggatggt gctcgtcgac
    91021 aggcagataa ttgagctcga ccggacgcgg tgcgaaagga aggccgagca cgctgaagga
    91081 ggaggcaaac aacaggcgtg aaatgcccgc ggcttccgtc gcggcgagca cgttgaacat
    91141 cagcgtcatg ttggtctgaa acacctggcc ggcatcgtat ccgaccggcc gagggatcga
    91201 cgcgatatgg gcaaccagat ccgcgtcggc aatgtggcgc ctggcgacat ccggatccat
    91261 gaggtcggct ccgatcacat cctccaggcc gcggggttca tgatccagag ccgtaaccgc
    91321 aaatcctgcc tggcgatagg ctccggcgac atgacgtccg agaaggcctg ccgcaccggt
    91381 cacgaccaca tgcttcctgc ccgccatccg catcttcctc ccgacccaag cgacaccgca
    91441 tcaattcgtg ccccaaccat ttttgcctga aaacgcgctt gacaaaccgc tcttttcggc
    91501 gccaacttta ttcgtatacg aacgatataa ctcgtcaagt ggcaactggg accacccgaa
    91561 gtcgggacgc tcgtaaccaa gaacaacacc agagaggaga acgttcatga acacggcttt
    91621 taaaaggatt ctcgcgggac cggtcgtggc tgctgccgtc gcttgcggct ccggtgcggc
    91681 gcaggcggag ccgctcaaga ttgctgcggt ttccggctat ttttcccaag gcttcggcat
    91741 ctcgatcgtc aacggcctcg agagagccaa gaaggacctc ggcgtcgagc tcaagatcgt
    91801 ggacaccggc aaccgcgcac tcgactacga agagcagttc aacaatctcg ccaagggtgg
    91861 ccagtacgac ctgatcttcg tgatgggttg ggaactggtg gacgctctgc agaaatccaa
    91921 caagacctat ccggatcagc gcttcatctt tatcgacggc gtgctcgaca gcccgaccat
    91981 gacttatatc gacttcgtgg aagaggaggg ttcctttctt gccggcgcac tggccggcat
    92041 gctgactcag gagaaagtcg aaggcttcga cagttcgtcg gaagtgggct tcctcggtgg
    92101 ccgcgacatt cccgtcatca gaaacttcat gtcgggaatg gagcagggcg tcgccaaggt
    92161 cgcatccgac gtcacggtga acggcgtctt cgccggtacc ttcgatgatc cggccaaggg
    92221 cagcgaactc gccatgaccc tctatggcca gggcgtcgat atcatctatc aggctgcggg
    92281 tccgacgggt gaaggcgtcc tccaggctgc caaagctgcc cgcaaatatg cgatcggtgt
    92341 cgatatcgac cagtgcggca cggcacccgg agccatcctg gcctcgatgc tgaaacgcgc
    92401 cgatgtcgct gtctacgaac tgatcaaggg cgaagccgag ggcaacaaga tcaagccggg
    92461 tgcggtcgct ttcggcgtga aggccggcgg cgtggagctc aagatctgcg acgaggtgaa
    92521 ggacaaggtt cccgcggaga tcgtcgccaa gctcgaagaa ctgcgccagg gtgttgccga
    92581 tggctccgtc gccgtcaagc tgaatcaata acgctccgcg accgaggggc agtttcgatt
    92641 tcgaacggcc ctttcacgaa agctccggtt caggcttgca ggccatcaac cgcggaatgc
    92701 ggacattttc ctgctctctc tacttgaacc gcgtcgacac tacgggactt tagcggctca
    92761 tgacctacgc gatcgaaatg caggccatca ccaagcgctt cggcacgctg gccgccaaca
    92821 aagacgtgac gttcagcgtg cgcaggggcg aaatccacgc gctcgtcggc gagaacggcg
    92881 ccggtaagac gacgttgatg aacgtgctgt tcggactgca ccagcccgac gagggcgttc
    92941 tggccatcaa cggccggacc gttaagatgg attcgccacg cactgccatc gcgctcggtc
    93001 tcggcatggt gcatcagcat ttcaagctcg tcccctcgct gaccgtcgcc gagaacatct
    93061 tcctcggcat ggaaatgacc cgaaacgggc ttatcgatcg caaggcccag tcggcaaagg
    93121 tcgcggagct ttccagcgcc ttcggcctgc atgtagaccc ggagcgccgc gtgatggatc
    93181 tgtctgtcgg gatcgagcag cgcgtcgaga ttctgaaggt cctcgttcgc ggtgccgaaa
    93241 tcatcattct cgacgagccg accgccgtcc tgacgccgca ggaaagccgc gacctctttc
    93301 gaattttgcg atccttcacg gagaagggca tgacggtggt gttcatttcg caccatctca
    93361 ccgaggtaat ggaagtttcc gacaccgtga ccgtgttgcg cgacggtcag gtcgtcggaa
    93421 cgaaaccgac gcgtgaactg acggaagacg aactggtccg catgatggtc ggccgcgacg
    93481 tcagctttgc ccgtcgcgaa cggcagccgg caaatggcgg gacggttttg aatctaagcg
    93541 aagtctgcgc ccgcgacgac cgcggcctcc ccaccttgcg cgatgtcagc gtcgaggttc
    93601 gcgcaggcga aattgtcggc gtcgtcggtg tcgacggcaa cggccagacg gaactcgccg
    93661 aggtaatttc gggactgcgt ccggtgagct atggcacgat atcgctcgct ggcaccgcgc
    93721 ttgaaaacgc cgacccactg acaatccgca agtcaggact ttcgcatgtg cccggcaacc
    93781 ggcttgcgcg tggcgtcgat gcgtcggcat ccatcgcctc caacattctg atgggccgcc
    93841 atcaaacggc tccttgggta cgccgcggca ttgtccgctg gtcctatgta cgcgaacagg
    93901 cgggcaagct gatccgccag ttcgagatcc gcgcgtccag cgagcgtgct ctcgtgaaga
    93961 cgctatcggg cggcaatatg cagaaggtgg tgctcgcccg ggaattttcg cagaacatgc
    94021 ccttcctcct gatcgaccag ccgacccgcg gtgtcgatat cggtgcgatg gagggcattc
    94081 acgacgagat catgcggcag cgcaattccg gcgccgcaat cctgctgatc tccgtgcagc
    94141 tggacgaaat cctcaagctt gcggatcgga ttctcgtcat gttcggggga cgcatcgtcg
    94201 gcgaggtgga tccggaaagc acgaccgagg acgaaatcgg tttccttatg gccggccgcg
    94261 catcgagcga ggcgaaagtg gcatcatgac gacagattcg agcgctacaa aatcatccgt
    94321 ggtaccggcc gcggaccgca agggtccccc cggctgggcc gagggcctga tcggccagct
    94381 tctcgccatc gccctgtcgc tggtcggcgg cgccgtcatc atcctgatgg tcggggaaaa
    94441 cccgctgcat gtgtttgcga ccctgttgcg cggcgccttt gggagcaccg accgaatcgc
    94501 cggctcattg ctgcaggcga caccgatcat catctgcggg gtggcggcct gcatcgcgct
    94561 gcgcggcggc ctcttcaaca tcggcgtgga gggacaactc tatctcggcg gatttgctgc
    94621 cgcatgggtg ggtttcagct ttgccatgcc gccggtgatt cacgtggtgg tggccgtcgc
    94681 cgccgcgatt ctcgcgggct gcctgtggat cctgatcccg gccctctttc gcgccaaatt
    94741 cgggaccaat gaggtcgtca cgaccattct tgccaattat atcgccgttc ttttgacgtc
    94801 ctatctgacg atctcggttt tcaaacggcc gggtggctgg tcggaaactg atccaatcgc
    94861 cgtaaccgcg cgcctgccgc agctactgcc ggattcccgt ctcaacatcg gccttttcat
    94921 cggcatcggc ctcgccatcg ggcttcacct ttttctcagg cacacgagcg ccggatatgc
    94981 catgggagcc atgggagcaa atccgaagtt tgcggagtac ggcggcgtca gaacacgtcg
    95041 caacgtcttc ctcattcttc tcgcatccgg agccgtcggc ggcctcgcgg gcggcgtcga
    95101 gacgctcggc gtgcatcatc gcttcatgga gggcttcgca ccggggttcg gtttcgacgg
    95161 ggtcatcgct gcccttctcg ccaacggcaa tccgatcggc atgatcggca ccgccctgtt
    95221 cttcggcgcc cttcgcgccg gatcgctcct catggaagtc gaaaccaatg cgtcgcgcga
    95281 aatcattacg gtgatccagg ccttcatcat cctgtgcgtc tcggcgcaga tcctcatccg
    95341 ccgtcgcagc ggccgtaccg gagagcgccg atggaagttc tagaaaagat cttcaatttc
    95401 gccctgatcg cagccacgct gcgcaccacc gcccccatcc tcctggtgtc gctgggcggc
    95461 tcgttcacca ccaaggcggg cattttcaac atcgggctcg aaggtcagat gctggtcggt
    95521 gccttcttcg gcgtgctcgg ttcgatatgg acgggctccg cgcttggcgg gctcctgtgc
    95581 ggtgtactcg cggctgtcgt gatggccgcg accttctcgc ttctcgtggt gacgctcagg
    95641 gcgaatgaag tggtcgttgg ccttgcgctc aacatcctag ccggcgggct gacgatctcg
    95701 ctgacgaagg ccattttcgg cacccgcggc tccatcgtca gcggcgacat cgtcggcctg
    95761 ccgccgatcg acattccgtt catcgaggat ctcggtcggt tcggccgggt tctgtccggc
    95821 tatacgcccc tcgtctatct cgcctttgtc atggtcttcg tggtctggct ggtgctctat
    95881 cgcaccaaac tcggccttta tatccgcgtc accggagaga agccggaagc tgccgaggcg
    95941 ctgggcatcc cgacggctct catgcagcac atcgcgtcgc ttctctgcgg ggtactcgca
    96001 gggctggcag gcgcgcacct gtctctcggc tatatcacga tgtttgcgga aaacatgtcc
    96061 tccggccgcg gtttcatggc ggttgcggtg ctgatcttct ccaatggcga tcccttgaag
    96121 gttctgctcg gctgcctgct gttcggcttt tccgatgccg cctcgctgcg gctgcagacc
    96181 ttcggttttc cgtcctacat cgtcctgatg gtgccctatc tggtgaccct cggcgcattg
    96241 ttcgccctga cctatcgcca gcggcccaag gttattcgcg aaacactcga aagcctgtcg
    96301 ctgttgcggc gcacctgatt aacggagttc aaatggaacg gatcattctc gatgtggatt
    96361 cggccgggga cgatatcctc gccatcctgt tttccgccgg ctgcgcggac accaaactcg
    96421 aaggcgttac cacggtcgcg ggggctgccg gcggcattga acaggtaacc aacgtcgtgc
    96481 tcaacacgct gacactcgcc gggcggaacg atatccccgt tgcggccggt gcctaccgcc
    96541 cgatcgtggg caatgccaag gcggacatgg aagcgcctgt gcatttcgaa aagcagttgc
    96601 aggcgcgttt cggcgaccga ctccagggtt tcaacccacc cgcccctgaa cccgcgtgca
    96661 aggcaatggg caagcatgcc atcgatttca tcgtcgacac cgtacgggcc aatcccggtg
    96721 aagtttccat cgtggcgaca ggtccgcaga ccaatgtcgc cctggcgctg cagatggcgc
    96781 ccgacatcgc ccggctggtg aagcagatcg tcgttctcgg cggctgcttt caaacgccag
    96841 gcaacatgac gccggtttcc gagtacaaca tctgggccga tcctgaagcg gcccgggtcg
    96901 tgctgcgatc cggggcaccg gtcatcctgg tgcccctcga tgtgtgcgag gacaaccgcg
    96961 tggcggcctc gatgctgacg cgcgacgacc tcaacgatct cgcaagcctt tatcctgcca
    97021 gcaaggcggt ctcctatgtc tgcgagacct tcccgatcta catcgatatc tggcgcgagt
    97081 tcttcgaact cgtaggcttt ccgctcgatg atgcgattgc cgtcgtcgcc gttctgcacc
    97141 ccgaattttt cgagatgacg gagccgctct tcgtcgacgt cgccctgagc gagcgcctcg
    97201 tgcgcggcca gaccgttgca ttccagggac gccagatcct gcccttctcc ggcccgaaga
    97261 cgacccgggt ctgccgcaat ctcgacggca ggaagttcct gtccctgttc aagaattcca
    97321 ttgggagcct gtcgtgagca aaaccgtgaa gacgataccc gtattgatgg attgcgatcc
    97381 gggccacgac gacgcgatcg cgctggtcat ggcgcatcgc tcgccggtca tcgaccttct
    97441 gggcgtgacc acggtctgcg gcaacgcgcc gcccgaacgc acgaccagca atgccctgcg
    97501 tatcatgcag ttcatcgacg caaccgacgt gccggtcgcg cagggctgcg tcacaccctt
    97561 ggcgcgtccg ctcgtgctcg gtaccgcgga cggcccgacg gggctcgacg gcaccacata
    97621 tctgcccgag gccaccatgc cgctggtgcc gatgcatggc gtcgatttca tcgccaagat
    97681 tttgcgcgag gcgccggagc cggtcgtgct cgtgccgacc ggaccgttga cgaacatcgc
    97741 catgtttttg ctcaaatatc ccgagctgaa gcacaagatc gacaagatcg tgctgatggg
    97801 cggcgccttc tatcggcgaa ccgaatatat cacgccgacc gagttcaata tcttctgcga
    97861 ccccgaagcc gcccgcatcg tgctcgacag cggtctagac attatcatgg tggggctcga
    97921 cgtcaccatg catgtgctcg tcgaggagga gcagttcgcc gagttgcgca agatcgagag
    97981 ccccttgggc aaagtggtgc tcgactggct gaagttctac gaaaagctgc atcgtgggca
    98041 gatgggcgtg ggcggcgcgc ttcatgatcc gctggcgctt gcagccgtca tcgatccgac
    98101 tctcatcgag acgcgggagg cgcatgtcga aatcgacctg accggaactt atacgttcgg
    98161 tgccaccgtt gccgacttct ggaacgagcg caagcttggc aacaataccc gcattgccac
    98221 ccgggtcgat tccgggcgct tcttcgagtt gatgtatagt ctgctccggg attgaccgtt
    98281 cagggaccgg caccgagcgt ccgcagcaag gaggcacgta tggacgacgt attttcggcg
    98341 catcgccgca acgaggacgc ggtgctcgat ccggcaaaaa cggccgtgat cgtcgttgac
    98401 atgatcaacg agttctgtaa gccgggcggc aggatggttc tgcccggtta cgaagcgctg
    98461 atgcccgcgc agaaggcgct cgtggccgcg gcgcggtcca atggggtgcc cgtcatctgg
    98521 gtggtcgatt cccaccgcaa gaacatgcgc cgcgatcgcg aatgggtgaa acgtacgccg
    98581 cactgtgtcg aaaacacatg ggcgacggag gtgatcgatg acctggagcc gcaggaaacc
    98641 gacatcacgg tcgtcaagca ccgttactcc gccttcttcc agacagatct cgacctggtg
    98701 ctcaaggaca tgttgatcgg gcagatcgtc gtcttcggcg tggtcaccaa catctgtgtc
    98761 cgttccaccg tgcatgacgg cttcttcctc ggctacgaca tcgtcgtgcc gcatgatgca
    98821 tgcgccgcca caggggcgcg ggagcacgcc tcgacccttt acgatatcgc cacgcatttc
    98881 ggcacagtgt cggacgcagc cacaatagcc gccgcaatcg ccggcggagt ggccattccc
    98941 aaccaggtct tcgaaggctg accgaatgcg aaagctgcac cacatgaaca gaaaaaagga
    99001 acaggcaagc cccggagaag agctttctcc ccgtctctcg caaaccgaga tcgacaagcg
    99061 gctggtcgag atcggctaca ggctcgaagc tcacaacgcc catctgatcc ggttggcgca
    99121 ccaaagggcg acgtcgctgt tccagaaggc cttcgagaac tacacgatca cgccgacgca
    99181 ggtggcgatc ctcgcgacgc tgcttcggca cggcgacctg tcgcagatca acctcggccg
    99241 gctgaccgcc atcgacacgg ccaccctgag cgccatgatg cgccgcctgc aggataacgg
    99301 cttcatcgag cgaatcccat cagaacagga tcagcgcgtc aatctggtgc gtctgacagc
    99361 gagaggcata gagttcacat tggaagtcct gccgatctct cagaaagtca gcgacgaggt
    99421 cctcgctccc ctcaaaccgc gcgaccgcga acgtttcatc gaaatgctca agctactggg
    99481 ctgaacgcac cggtaatccg ctgcaggccc cgctctcagg agaatcttat gccccaattc
    99541 atcgtccgca aatccatcac gctcgttgag gacatctttc acgacggcgg tccggtagca
    99601 accgtcccgc ggcgccgcgc agcggccgtc gcaattgtca gcaatccctt tgccggacgc
    99661 tatgtcgagg atctgcagcc cgccatggaa gatctgaagc cgttgggcct acggatgacg
    99721 gacaatctgg tcggagccct cggcggcgac acgtcgctga tcgatggcta cggcaagggg
    99781 gttatcgtcg gttcggcggg tgagctcgaa catggcgcgc tctggcacgt tccgggcggc
    99841 tatgccatgc gcgaacgcct cggagaggca ttggccatcg tcccttcggc taaaaaggtc
    99901 ggcggcttcg gcgctcgcat cgatatcccg atcggccaca agaacgccgc ctatgtgcgc
    99961 agccacttcg acgccatgga gatcggcgtt ccggacggcc cgcgccccga tgaactccta
   100021 ttgtgcctgg tgatgacctg cggcccgcgt attcacgcac gcatgggcgg cctcgccgcc
   100081 tccgacatca aggccttcga cggattgcgt tgagactaca cgaagacccg gtaaggaggg
   100141 agccggcaac gctctctctt tctcggtcaa ggcacatcca tcttttcgcc agggagccgg
   100201 gtaagcggct tgttccagcc gatcaactgc agcctgctcg gatgcccccg gccccctcgc
   100261 gctacacgcc gaaccgccgc agtagatgtg gaagacaggc tcggccagtg ctgaagtttg
   100321 ggaatcggga gagaagccgc cagtgagatc aggcgccttt cgagcggcgg cggcgcaact
   100381 tttcggtcgc ttccctgtca agcttgccgc ttgtcgtatc gatcacgacg ccgaagaggc
   100441 tttctgcctg ctgcagcgag taatagccga ggaacacgtc cttgagcacg gcctcgacgt
   100501 cccgttcgtg ggccaggccg tatccgccgc caccgggggt ctccacccgg acccggtccc
   100561 cggcggtcag tgctatgtcc tgttccttcg acagatgttc cggccgatag gtttttccac
   100621 ctcgcgtgac cgtgatcgtg cccactgcgc catccgcgcc gccgagggcc ccctggggtc
   100681 cgaaggcgcc gtgatccatc acgaaggatg cctgggcgtc gccgcgcagc aattccactt
   100741 cgtagctgag gccgaagccg ccccggttgc gtcccgcacc gccggagccc tcgtggatcg
   100801 cgtattcgcg gaagaacacc ggaaaaacct gctcggtgat ctcgaccggg gcggacttgg
   100861 atatgccgat ggtggagcag ccgttggtca ggccgtcttc ccgggcgttg ccgccgtaac
   100921 cgccaccgga aatgtggtac atcacgtagt cgcggccaag cagcggatcg ctgccgccga
   100981 gtgcgaaatt gccgctggaa ccggcgggag ccgcggtcac gcgctccggc agtgcctgta
   101041 cgagggcgga aaagaccgcc tcggcgatgc gctgcgacac ttccgccgca cagcctgaga
   101101 ccggccgtgg atattgcgca tcaagaaacg tgccagcagg gctgacgatc tccagcggct
   101161 cgaaagcgcc ggcgctgagc gggatctccg gaaagatgtg ccgcatggcg agatagaccg
   101221 aggagtgggt cgtcgccagc acgcaattca tcgggccgcg gcagggcgga ctggaccccg
   101281 cgaaatcgaa gaccagccgg tcgtcgccgg tcttggtcac agacagggca atggtgagcg
   101341 gttcgttgac cactccatcg gaatcgatga aggctttgcc gtgataggtt ccgggcgcga
   101401 tggtgcggat ggaggcgcgc atctgcgctg ccgagcggcg cctcaattct gcaatggccg
   101461 ccgctaccgt gtcgtcacca tagcggtcga gcagggccgt gaactgctcc ttgccgaccc
   101521 gcaaggcggc cgcctgagcc cggatatcgc ctatgcgctg ctctgcgacg cggatgttgg
   101581 agctgatgat cgagaaaagc tcgcgatcga gaacgccgcg cttgaacagc ttgatcggcg
   101641 ggaaacgaag tccttcctgc tccacggagg tggcggatgc cgaaaacccg ccgggcacgg
   101701 cgccgccgat atcgggccag tgtccgatgt tcgagagcca gcagaaaatc tccccgttac
   101761 gatagaacgg cgtggcaaag cggacgtcca tcaggtgcgt gccgccaaga taggggtcgt
   101821 tcaccgcata gatgtcatcc tcctccggcg gcaggcagcg gccgtcgcga atgaactcga
   101881 taagagtgcg ggtcgatgcc tgcatcgttc cgacgaagac cggcagcccc ttgatgcctt
   101941 gggcgatcag cgaaccatcc tcggcggaat agatgccgtc ggagcggtcg tccgcctcgg
   102001 cgatgatcgg cgagaatgca gctcgcgaga aggtcatgtc catctcgtcg cagacctgct
   102061 ggaggccgga ttggataacg gtcagggtga tggggtcgat ggtgctcatg cagcgggtgc
   102121 cccgatggtg atgatgatat tcccgtggac atctcctttg gccacgtcgc ccggattgat
   102181 gaccgtggtg gcatccagct gctcgaggat ggccggccct ttgatctcgg cctggagcgg
   102241 cagacgctcg cgcgcataga ccggcgtgtc ccaccacgca ccatcgaacc agaccggtcg
   102301 gacttccaat tgggcttcct tcagtatcgc gcagcgcccg tcattcggaa tgagatcgtc
   102361 gagggagatc gccttgcgga tgccgataac ggaacagttc aagctgacga tattcgcccg
   102421 gacttccgga aggcggacac ggaagcgatc gtaataggcg gcctcgaagc gcgcctgcag
   102481 ttcgtccaga tcgatcgccg catccggcag aggcaccctg atcagatggg tttgcccgac
   102541 gaactgcatg tcggcgctgt attcgacctc gatgcgttcc ggtctcaccg cctccagttc
   102601 gatcgcgtcc atcccggctc gggtctgctg ctgcagaatg gcgttcaaat gcgcagggtc
   102661 gctgtccagc agcggcatgt tgacggtgtt tacatagtca tgccgcagat cggcgacgat
   102721 acagccaatg gcattggtga tgcccgggcg cgccgggatc ataaccctcg gaatacccag
   102781 ttcacgcgca atcgcagccg cgtggagcgg ccctgcgcca ccgaaggcga aaaggatgaa
   102841 atcacgggga tcgttgccct ttgcgatcga aaccatgcgg atggcaccgg ccattttcat
   102901 gttcgcgatc cgaaccgtcg cctccgccgc atgcgcggca tcgaggttca agcggccgcc
   102961 gatacgatcg gaaaatgcac cggcgatcat ctcgaccgga acaggcgaat ccaccgccag
   103021 cagctttttg gaattgagcc tgccgagcac gatattcgca tccgagatcg ttggctcgac
   103081 gccgccgcgg ccatagcaga tcggccccgg cgttgacccc gcgctctgcg ggccaacccg
   103141 caacaggccg gcctcatcaa cgcgcgcgat cgacccgccc cctgcgccga ccgtgtgcac
   103201 atcgaccatc ggcacgtgga tgggcatcgc atattcgact tcgatctcgc ttgagacgag
   103261 aggccggttg tcgcggatca gcgccacgtc cgtggaggtt ccgcccatgt cgtaggtgat
   103321 gaggttgtcg tatccggctt tcgcggcggt gtaggcggcc gcgatgacgc ccgatgccgg
   103381 tccggacatg acggtttttg ccgcttctcg ggacgccagc cgtgatgaga tcgttccgcc
   103441 gtttccgttc atgatcaggt agtcacggct gtagccgctc ttttccagtt cgacccgcag
   103501 gcgctccacg tagcgttcca ggatcggctg caccgatgca ttgacggaag ctgtaacgcc
   103561 acgctcgaat tcgcgcgcct cggaaagcag ggaatggccg gtggtgatat aggcgttcgg
   103621 ccagaattcg cgggctattt cggccgcttc gagttcatgc gcggggtttt tgtaggaatg
   103681 caggaaatgg ataaccagcg cctcgcagcc ggcctcgatc agctgccgca cggctgatcg
   103741 cacacctgtg gcatcgagcg gcgtcacaac ctctcccgtt gcctgaatgc gctcgtcgac
   103801 ttcgagccgg aggttacggg ggatgaccgg cacgaaggtt ccgaagagtc cgtaagggct
   103861 cggccgcgtt cgccggccaa gctcgatcac atcccggaat cccttggtgg taatcatgcc
   103921 cgcgcgcgca atgcggcgct ccagaagcgc attcgtggtg gccgtcgtac cgtggatgat
   103981 caggtcgatc gaggcgatgg gacggctcga tttcgcaagg gccgaaagga cgccgtgcga
   104041 ctgatcgtgc gtggtggtgg gaactttgcc gatctggacg gcgccggtgc tctcatcgac
   104101 gatgatgaga tccgtaaacg ttccaccgac atccacgccg gcaacagttc caccggacct
   104161 ttctctgtcc tcgctccaca tgatattccc gctatggctc tcgtcagatt tttgacaatc
   104221 actgataatt aatttgtaca cgaattaatt ttcattgcaa gattgcatca gacgtagcag
   104281 gcctcgagtg gaatttgtgt ccgagcgcgg caagggcaca cttctggtgc tgtcttggat
   104341 gcgactatga agccatccag taatggacga ccaaagaagc gaagccggac tatgctctcg
   104401 gacttccgaa gaaagcggag ccgatctaag gtccctcggg ctcgtcggcc ttcagatcct
   104461 gctcggcctg ccgaaccttt tggcgggtaa agccccgaag cccggagact tcctccgcgt
   104521 cacgctcgat ctggacctcg cttgccgcgt gatacaccgc aagcttcgca accgacatca
   104581 gcgcgtgaag atggatgcgc tcatagccgt gcgacgcgtc gacgccgaag gtaagaagcg
   104641 ccgtgcggac gtcgtgcccc gcttcgagcg cggatgcggc gtcggagcga tagtagcgga
   104701 agacgtcctt ctgaacgcgg atgccatgct cgccgcaaag ttcgtagagc tttctcgaga
   104761 gatgatagtc gaagggccct gtctggtccg ccatggcgag cgtaacgccg aactcgtccg
   104821 aattctggcc cggcgcggtc gtaccgttgt cgatcgccac cagagaggcg atttccggaa
   104881 cgattgcagc cgaggcgcca acgcccacct cctcgccgat ggtgaagagc caataggtgt
   104941 cgaccggcgt ttccaccttc tggcgctgca tggcctcgag cgccgcaagc atgatggcca
   105001 ccccggcctt gtcgtcgaga tgccgcgaaa cgatgaaccc gttgtcgagg aactcgggct
   105061 ggggatcgat ggcgacaatg tcgccaacgt caattccgag ctgcaccaga tcgctccggt
   105121 cgcgggcaag cgcatcgacg cgcagctcga tgtgccgcca gccggtcggt tgcgtgtcga
   105181 tctcgtcatt gaaagtgtgt ccagaagcct tcaggggaag gatggttccg cgataggttc
   105241 ccttgccgga aaagatcgag ccgcgagccc cctccgcgaa ccgcgccgac cagtggccga
   105301 tcgagaccag ttcgaggcgg ccgttctcct tcagcgcctt cacctgcgca ccaagcgtgt
   105361 ccaggtgcga gacgatcccg cgggctggcc gttcggccgc acccggccgc atagcgcgaa
   105421 ttgcgccccg gcgggtcagc ttcacttcca gcccgagacg ctcgagctca cgcgcggtgt
   105481 agcgcaccgc ctcatcggtg aaaccggtcg ggctcgcaat ttcgagcagg gctttcagcc
   105541 ggctggtgag gtagtccggg tctatattga tcggtgtctg catggagtgc gttgtcgcaa
   105601 tcatggatgc tcgcgtcaac aattgcctga cacacctgag ctcataaaga gcatcgcgcg
   105661 catcgacggt ttcgaacggg aacatcgctc ggcccgccac gttgtagggt actcagctct
   105721 tcggcatggg cggacgagcg ttattcggga ggtcgcgtgg gcaaatccgt gaacgaaaag
   105781 caaagcgctc cactcattca cggagccagc gatttgccgt cagtgacggt cgacggctac
   105841 aatctggaac tgcgtgacgg cgacggcttt ctcggcgaca aggccaacaa atccgcgttc
   105901 caggaaaaac tcgacgactg gcgcaaacgg gtgcgcaaag gcggcgacga cccgctggga
   105961 gaggcgctca cccaggacct gtccaagaaa cagatcgacg ctcttcttcg tggtgacgac
   106021 aagcaggcgg ccgccctcat catgggagcg atggacgaat tcgccggcga gctggccggc
   106081 gttcttgaga aattcctgca gcagaagagc tggaagaact cggaacgtgt cgtgatcgga
   106141 ggcggcttca gaggaagtgc cgtaggtgag ttcgcgattg cacgggcgat ggtgctgatg
   106201 aaggcaaagg gtatcaagat cgagctctct cccatcgttc atcatccgga tgatgccggg
   106261 ctcatcggtg ccgcacatct catgccagcc tggatgctca agggacacaa gaccatcctc
   106321 gctatcgaca tcggcggtac caatatccgc gtaggcatcg tcgagctgcg tctgaaagat
   106381 gatacggacc tttcaagggc caaagtctgg aaatcggaca tctggcggca tgcggacgac
   106441 aaacccaaca gaagcgccac gatcgaagca ctcatcggga tgatcgaaaa gctcatagcc
   106501 aaggcggaca aggcggatct tgcaccggcg ccggtcatcg gcgttgcctg ccccggtgta
   106561 atcaatgcgg atggctcgat cctgcgcgga ggccagaacc tgcccggcgg gaactgggaa
   106621 agcgagcatt tcaacctgcc tgccacgctc aaggacgcca ttccgcagat cggcgatcat
   106681 gagaccttcg taatcatgca caacgacgcc gtcgtccagg gcctgtcgca agtaccattc
   106741 gtgcagaatg cttcgagctg gggtatcctg acgatcggga ccggtctcgg caatgcgcac
   106801 ttcagcaaca aagccggaaa ttgacggctg cagcaagctc cggtgcgctt cgacgcagcg
   106861 cccgaacact ggcgtaacac gcggaatggt taagggctcg gtgcacagac ccggcgaatt
   106921 gtcctatttt cctcgaccgt gaattaaatc gtttcgacta acctccttca caatgaaaaa
   106981 cggggagttc ctactgtgaa ggtcaaatcg acagcacgat ccggtctgtt ctgcacccac
   107041 cggacgatcg tccgcagcac tctcgcggtg atggtcgccg cggctagctg cggctgttcc
   107101 tcgacggtca gtcaggagac gacctcgtcg atcacgcgag aagccggcta ctccattccg
   107161 gaccaaaagc ctgcgccggg caagcaagcc gtcaccaaaa aagcgaacaa actcgtccgg
   107221 tcggcctatc tcggtcgggc tccctatatc tgcacgccga gtggtttcgg cagcacctcg
   107281 cgctgctttc ttcgttaaag cctttcctgc taaatcgaaa aaagcagtcc gggagaagca
   107341 ttggcggggt tgcgggcatt cgaccgggct catctgtgga gccagtttga actgctgaca
   107401 tcggcagccg cgcaacccct tcccggccgg gttactcttc cccgccgagt ctcgcctcga
   107461 tgcggttcag cctggcgccc acataattgc cgcgcctaag cttgacgaac tcgtcatctg
   107521 gcctcacctg tgcgttcttg aagacgtacc aggcgccgtc cggttcgcgc ctctgataga
   107581 tcacgccagc gcgctttcgg tggctgaagc aggttgtcgc tggcgccgag ccgtcctttg
   107641 catgccaatc ggcacggaag cagagctttc cggggccggt gatgaaccag cggcctacgc
   107701 cgtaagacgg tttgccgttt tccttcgacc aggcggtgaa tcggcgcgcc tgcactgaga
   107761 aatagcctgc gccctctttc cagatccacg atttttggcc gtagagctgg aatagttccg
   107821 cgtgtgtcag tgcagttgtc ttccggtcgg cacgcgcggc ggcagcctcg gcaaaagatg
   107881 cagtggcaag gccggcgacc aggacgatgg ctaacggtat tcctcggttc atcgatttca
   107941 tcacatgcct ccgtcgggcg cttgcccgct gatggtttcg cggacgaccc gccaatcggg
   108001 gcggccatag ccttgcggcc agtcatagat ctcgcgatcg ttgaaataga ccacggctgt
   108061 cagttgcgga aattcggcgt gacgctcagc aacggatgcc gcccagctcg cgacgtatga
   108121 gccatcgccc tcatagccga gctcggcgac catgaccggc ttgccgtagt tcatcacccg
   108181 tccgtaaccg ggcgccagcc gctccacgaa cgtctgagcg cgcccggtcg tgccttcgtc
   108241 gtagggttgg tagccgaata ccgaaagccc gacgatatcg acgacatcat cacctggata
   108301 gaaggcgtcc aacccctcgt tccccttggg cgaccacatg aatttcgcat tcttgagatg
   108361 gccccggcag acgcccacca cgtgacgata ggctgccttg aagtcctcgc cccgccaatg
   108421 cgaccaggag aactggttgt cggtttcgtc catttcctgg ccccaacgga tgatcaccgg
   108481 gcttttcagt gccgccgcgg ccgaacagac ctgggccatg ttctgatccc gctcaccgct
   108541 cagaatcgaa cgcaggagct cttcctcggt cacgcgccac tccggcgacc acgaccaggg
   108601 ttcgatggta atcaggagcg agcggcctcg cgcctgggca tagtcgtcgg caagcgcaag
   108661 ggtcgacaga tcgacgtctt cccagggcag gaagagatgc tcgatcttcg agctcccagg
   108721 cgtgccgaag tcaccatgag gatcgtaagc gccgaaatcg agggaagtct ctgtcagcac
   108781 cggccgcttg tccgatggcg ttgccttcgt cggcgagttc tcgtcgggga tacctcgagg
   108841 catattggct gcgagcactg tccccgacag caatagtccg agacatccga acgcaacggc
   108901 ctttgatttc ctgttcattg cacacctcca actgcgttca tgccgacttg ccggcgaacg
   108961 ctatcctttg tctggttgac ttggtccgtg aggcgctcct tgaccatcgg gagcttgggg
   109021 tcgaccaggt cctcatcgac cagtcggtta aactcgtcgt ccgcccgccg cttggcatgt
   109081 ttgaaaacgt accagtcgcc ggctggctct ctcttttggt agatggtgcc gtcgagcgtg
   109141 cgatggctga agcaggtctt atcggagacg gtggcattct ggctgtgcca cacggcagag
   109201 aggcagagct ggccacgatc attcacgctc cagcggccct cggcccaggt ctcgcccgag
   109261 cccggttgaa cccaggcacg aaacacacgg ccctcacttt ccatccggcc cgcaccactt
   109321 tcccatttcc agctcttgcc gcggaagatc atgtagagct cgaccccggt catggcgcgg
   109381 gcctcttcgg gaacggcgac ctcggccgac gccggcgact ggaagaggaa aagggcgact
   109441 ggcaagatgg cgagggcaag gcgcctgccg agcagcgcat aacgggtgct gcggccctcg
   109501 ttcctgacga acgtgaattt cgttttcatg ttcctacccc ctctctgctt tgccgccgcg
   109561 cggggcggaa atccaacgcg gactgaagac gatcttgcgc aaagtcgttc cgccctgccc
   109621 ggctccggcg actgcatagc ggtcctcgaa cagacgcagg tgaccgctgc cccaggcgag
   109681 cgcctcaagc ccttctttcc cgtgctcagc cgttgctata cctggcagcg cgatgacagc
   109741 caggagcccg gccgtgatcg cggggcgata gaagcgggaa cccgctgcaa cggcattttc
   109801 tctcgaatgc ctgatgacga tgacaagcag aagcaggcag taaatcgcag cattcaagat
   109861 agcgaacagg tagaagcccc tggccttcgc tgcatcttcg acgaggaaca ccggcaggac
   109921 ggccgcaatc gcaagcgcga agtagggcgc gagcacacgc agcggcaacg gatcgacctc
   109981 ggatgatccc ttcggcgtga cgcggaaatc cacgaaggac ccggtgagcc aatcgcgcag
   110041 ggccgccagc gtcccggcaa gcgcccaggg ccagcgcgcg aagaggaaaa gcatgcactc
   110101 ccagctgaga accttcgcgt cgcaggggcg gaaggcgccg gtcgcccgcc accgataagc
   110161 cagaaggacg agaatggccg acaatggtgc aaaataggcc agaaactccg gatatgttac
   110221 ggcaacaaag gtttcgccac gtgcaagagc tacgataggc atcgcgaaca tcagggccat
   110281 gaaacaggcg aaaagcggat accagagctg cgcgaagaga aactggaact tcaaccgcag
   110341 cggaagccgt ccgacgagcc gtggcgaata ctgcagaagc agcatgacca ggctgcgcga
   110401 ccactggaat tcctgggtga ccagatcggc aaaagtgcgt ggtccgtcgc catgggcgat
   110461 cgcgtccagc gcgtgaacgc cgcgccaacc tgctgcattc atcatcaatg tcgtcgaatg
   110521 gtcttcggca agttcagggc cgagcccgcc gatctctttg agcgccgccg tccgcacggc
   110581 gtagtgggag cctatgcaaa gcggcgcgag cccgccattg tagccggcct gaagggcccc
   110641 gtgcatgctc gcttccgcat agagccgccc gcgggccgac cagctctgcg aagcattgcg
   110701 gtcacagata ctcggcgccg agacgtaacc cacttccggg tcggcgaagg ggcgcagtac
   110761 ttcaaagagg taaccgggtg cgggaacatg gtccgcgtcg agctgagcca cgaaatcgta
   110821 accgtcatat ccgtagtgat cgtagaagaa ggcaagattg ccctccttgc agcgcgtacg
   110881 ccgtggccat gtggcccggt ggtagtctgc caggcctttg cgcgtcgaca cgagaacgcc
   110941 atgcctgcgg caccagtcga gtgtcgcatc ggacgggtcc tcgtctgcga gccacgtgtc
   111001 atgtggcacg tcctgcgcga gcatcgcctt caatgtttcc gccacgatgg caaaaggttc
   111061 cgatggcgcc ttggtaacga ccatggcaac gcgacttccc gtcgcgatcc gcagcggccc
   111121 gtttggtttt gccgcgcgat agaaaactgc aatgaaatag gcaggcagaa gggttaccca
   111181 cgcaaggacc gcggtcacga tggcgctgcc caaagcgtcc acgtggtggc tcggctccag
   111241 ccaccacgcc cagaaataca ggagtgcggc tacccagagc cccgcaccga gtagatattc
   111301 caaccggcgt cggcccgtga acacaggcac cagcagcggc tcgccgccgg cagacataat
   111361 cgttgacttc ttggcggaaa tgcgggtcat gaccgcgcct ccagtccgaa gaaaggggcc
   111421 gccgttcgta cgatagtctc cagatcggag taacgcggaa gaaatcccag tgtccggcat
   111481 gcaagcccgc catccgcata aagcgttggc gggtctccaa agcggcggcg gcgaaagacg
   111541 acaggaacat cgcgtccggt aacctcgacg attgctcgca ggacttccct gatcgagaag
   111601 ccgcggcctg tgccgacgtt gattgcgagg ttttcgccac ccttggcgag atgccgatat
   111661 gccagcacgt gagcactcgc gagatcagac acgtgaatat agtcacgcac gcaggttcca
   111721 tccggggtat cgtagtcctc gccgaaaatc tccagatgca aaatcgtgcc ggccgcagcc
   111781 atcagcgccc gcggaatgag gtgtgtttcc ggatcgtgcc attccccgag gtccccctca
   111841 ggatcggcgc cgcatgcgtt gaaatagcgt agcgcgacgt agttcagctt gaaggcggcc
   111901 gcatagtcgg caagcatgtg ctcggccatc aactttgtct tgccgtaggg attgatggga
   111961 tcctgcggcg tcgtctcgtg gatggggagc acagccggca cgccataggt ggcgcagctc
   112021 gatgagaaga tcaccttgtc gacgcccgtc cggcggcatg catcgaggag cgacagcgtc
   112081 ccgcggacgt tgttgttgta gtattttgcc ggatcggcaa cggactcgcc gacataggcg
   112141 gatgcagcga aatggatcac cgcgtcaggc cgatggtatt ctaacacctc gaccaggtgg
   112201 tttccgtcca gaatgtctcc gagaacgaat ggtccccagc gaaccgcgga gcggtttccc
   112261 gttgtcaggt tatcgtagac gatgggctcg atgccctcca ggcgcagaag cttggcggtg
   112321 tggctgccga tatatccggc gccacccgta accaggatac gtggcgctcc catcagacca
   112381 gctccgcatt ttcccgtgtc gaccgggaga gaacgccgtc gaaatatctg atcgtttgcg
   112441 caaggccttc ggccagattg accttcggac gccagccgag ctctttggtt gcgagcgaaa
   112501 tgtcgggtcg gcgctgacga ggatcgtcaa ccgggagggg cagccgaacg atcttcgaac
   112561 gcgaattggt cagccggatc acctcatcgg cgagttcgcc gatagtgaat tctgtcggat
   112621 tgccgagatt gaccgggccg gtaagcgacg cgggcgatcc catgagacga acgaagccgt
   112681 cgatcaggtc gtcgacgaaa cagaaggaac gcgtctgcga gccgtcacca tagatcgtga
   112741 tgttctcacc tttcagagcc tgaacgatga aattggaaac gacgcgacca tcatccgggc
   112801 gcatccgggg gccgtaggtg ttgaagatgc ggacgatctt cgtttcgacc ccgtgcactt
   112861 tttggtagtc gaagaacagg gtctctgcgc agcgcttgcc ctcgtcgtag caggagcgcg
   112921 gaccgaagga attcacattg ccccaatagc tttccacctg cgggtggacc tgcggatcgc
   112981 cgtagatctc ggatgtggac gcctggaaaa tgcgcgcgcc acggcgcgcg gccagatcaa
   113041 gcaggttcaa cgagccgatc acacaggtct tggtcgtctg aatcgggtct gcctgatagt
   113101 gcggcggcga tgccgggcag gcaaggttgt agatctcgtc gacctcgagg tcgatcgggt
   113161 caacgatatc gtgggcgatg acacggaacg tgtcgtagcg cttgagcggc gcgatattgc
   113221 gtctcaggcc cgtggagaaa ttgtcgaggc agatgacttc gtgcccggcg ctcagaagca
   113281 gctcgcagag atgcgacccc agaaagccgg caccacccgt aacaagtatg ctcttctgga
   113341 tgcttcggcg tggcagtgca tccctgtctt catgtacgtt taagagagtt tttttaaaat
   113401 cgttcctgaa atagttcacg gaataatcct cacactattc tcaaattctg aaaattcatt
   113461 cccagcgaaa acaataaatt ggtgatcgaa actttagcgc tcgaaactac ctaaatcatt
   113521 tgtcagcaat gcttggaacc actgtaggta actaatacaa tttcagggtg ggtgatgtcg
   113581 ttatcgcaca atcccaattg ttatcccgcc gtgcatttct acatataagg gagtatgaat
   113641 cgggaactgg cgggtgtgcc ccgacgattc ggttccacct tgaggcgaaa tgcagcaggg
   113701 cgggacaggg ccacagccct tattgtcgct cgtttgggtt cacccttagg ggtgagccat
   113761 gtcgctgggg gagttgtatg accaaggact ccggatcagg agatgacccc gtcgaagttc
   113821 cggcttggcc cgcccatatg gagcggcgcc gctggccacg cgacccatca gctcggaagg
   113881 atcgttcggc cgaacgatca ccggcgctcg tgccttcacg gttctcgacg cgtgagctgc
   113941 cgttggagga gcaattcaag tcctggcggg cgcacatggc gcctctcgtg gacgtgcatt
   114001 tgccggacgg ggtaaccgaa gaacacggct tcccggctga gctggttggt tggcacctcg
   114061 gtgatttgct ggtcgttcaa cagagtacgc ccgcacatag ctatgagcgt tctcaggcga
   114121 tgttgcgttc aagcccgatt gaccattgga atgtcgggct ctttcgcgcc ggacgatcgt
   114181 ggaccgaagc cgaccggcgc gtgacggaaa caggccccgg agagttcttc ttccgatcgc
   114241 tcggctatcc ctatcgcgga cgcatgacgg acgctgcggc tatccttctg ttcatgccct
   114301 atgaactgct tgcagatgat gtgggtaagc tcgaaggtgc caacaattcg gtcttgacgg
   114361 gtagtctcgc cgatctgctc gcgaactacc tcaacggcat ggaagaaaac ctcggcaaca
   114421 tcaccgtgga agaagtgccg cgcatcgtcc gtacgatacg cgacatggtc gttacatgcg
   114481 tcgcggcagt gagaccggat accggaggct cccaggcgaa gatgggagta atggagcggg
   114541 cgcaccgata tatccatctc aacctgcact cggccgacct cacacccgaa tcgatttgtc
   114601 gggagctcgg cgtctccagg acacgccttt atcaactttt cgagccgagc gggggcgtac
   114661 tcaactatat tcgaagacgc cggctgctgc aggcccacgc tgaactcagc gatccaacga
   114721 actaccgccc gatcgcggag attgcggaaa cagccggctt cgacctggcc gccaacttta
   114781 ctcgtgcctt cagccatgaa ttcggcgtaa gcccgcgcga agtccgcaag gcggcagccg
   114841 ccgatcgtct tgtcaccccc gttgccgtgc cggagcgcga ccgcgggtta acgatcggcg
   114901 actggctcag atcgatacaa ggatgagggt tgagccgatg acgataccgg aactgctgtt
   114961 ttccagactc atgcattcgc gccgccgtcg atcgtcaacg atgccccact gacgaatttt
   115021 ccatccgggc ctgccagcca tgcaacgaag ccggcaatat cttgcggctc accgaagccg
   115081 ccggtggcga tgcgttctcg ttgagcttcc gcatgatcgc cattggccgg gttcatgtcg
   115141 gtgttcgtcg accctggatg aacaatgttc acggtgatcc ctctcggtcc gaggtcacgc
   115201 gccagacctt tcgtcaggcc gatcagagcg gccttgctgg ccgaatagag gctgatcccg
   115261 ggccatggaa ccagttccgc cagattgctg ccgatcgtga ttatcctgcc gccgtcgccg
   115321 agatgtcttg atgcggaacg gatagcgacg aagggcgcgc gaaagttgac cgccatcacc
   115381 tcgtcaaaat cggcgacggt cgtttcgtcc agaggggcgg agtgccagat gccggcgctg
   115441 ttcaccaata tgtccagccg gcccagggtc tcggctgcat ggcgaacggc gcgttcgatg
   115501 ctttctgcgt cgcggttatc ggcccgaatg gcaatggcgc ggccgcccgc cagctcgatc
   115561 tcagagacga ccgcctgcgc ctggtcggcc gaattgacgt aggtaagtgc caccgacgcc
   115621 ccttcccggg caagtttcct tgcgatcgcc gcgcctatac ccctgctgcc gccggtaacg
   115681 aaagcggcct tgccggccaa agcacccgtt gtcatcgtgg attccttttg tagtgatcga
   115741 tacacaaaag gtgcctgagc ttgccaactc ttgtcaagcg atatatttat cgatcactac
   115801 agaacgagtt gatcaatgcc cgacaaaggc cgccccagaa gtttcgatcg tgccgacgcg
   115861 cttatgcgcg ccatgcaggt tttttgggag aagggttttg agggcgcctc gctgacagcg
   115921 ctgaccgcgg ccatgggtat caatgcgccc agcctctacg ccgcatttgg ctgcaaggag
   115981 gcgctctacc tcgaggcaat ggaactctat gcgcaaacgg tcggcaccga aatttggcaa
   116041 ccgatggaaa cagcaccgac cgcaagggag gcgttcagcc gtttcctcgc cgcgacagcc
   116101 aaggcctatt ctcagccgga taccccgcat ggctgcctga tagcgcttgg tggacttcat
   116161 cagtccgcaa taccgaaagc ggtctgcgat gcgctgtccc ggcaccgcac ggagaacgtc
   116221 gataaactgc gtcaacgtct ggaggccgcg atcgcggaag gtgaactgcc cgacagcctg
   116281 gaccccgagg ctgtcgccac cttttatgcc acggtacagc acggaatgtc gattcttgcg
   116341 cgggatggcg gcagttatca aacgctgaaa aacgtcgcgg acggagcaat ggccgcttgg
   116401 ggtatgttga cgcgggagga cagcgtccgg cgcccataaa tcacgatgat ttaagctcgg
   116461 atcgatcgaa acggttggag cgggatgcag gcggaaagtc gcgcacgtgc ttccccgctc
   116521 caaggagtat tcagcttttc aggtctactg gtttactgga cgacctgcac taccgttcgg
   116581 ctcttcggct cgacgatgac gcgtttttcg ttgacgaccg cataggcata acgcgaatcg
   116641 tcagggatcg gcgtaacaac cactgtttca ggcagcggtt ttccgacgac gatctcctgt
   116701 tgaaccacca ccggctccgc cggcagcggc tgcgtctcga catactcaat gatcttcggc
   116761 ggcggcgggt ctatggccgc acccgcaacg gctcctgcga cgcctccaac ggcagccccg
   116821 acaggtccgc ctacgactgc acctgcagca gctccgccgg ctgcgccggt tacggcgctg
   116881 ttcttggtcg tgctctgcgc tgctgcggga gcagcgaaac agccgagtcc aacacccaga
   116941 acaatggcac ctttgatgat cagatttttc attaggcatt ctcccgtatg cgaattgcgt
   117001 cccttcgggc agaacaaccc cctgactcaa gacttgttcc gagcgcaata tccaagagca
   117061 tgcgcagcag cccgcaatgc gcgatgcgaa aggaagcgat gcgggcgatg aaatgtattc
   117121 ctgttctctt cagccggagg cgcgtgcgag ttccgtgaat cggcgcacct cgttcagcct
   117181 agcctcaggt cgacacccgg atggagtttt ttaagattcg gcagggattt cgactgccag
   117241 gggaattctg agcttccgcg aacagtgaac tgtatgttcg gccgtttgcg tgcttcgatg
   117301 gtgagcttgg cgagcaggtt gattcccgaa gaattaagaa actgcagccc cgtgagatcg
   117361 acagtcatgc gctccggctc ggcttcgagc acgctcgtca cgagggcgaa gatcggcgca
   117421 taggcctcgg tgctcggcag gcgcatcgtc ccgtcgaaat agatgtcgtt tccttccgac
   117481 caaacgcgat attcgtcttc cttgatttcc atgtattcgg tgcccatcaa ttcgagaggt
   117541 cgggaattgc gattgaggca taggtctcca gcgggatctt gccatcctct tcgccggatc
   117601 caaaaaccca cgcgaagtga gcaccataat cgctcatgag ggtgagaagt ccaagcccgg
   117661 aacccgatcc cgaacctgtt gcatttgcct ctatccgctg tatcagaagg tcggatggat
   117721 ctcctatcgt tatttccgaa aggatgtggc ggaacgtgtc ggctgttcct ttgtccacga
   117781 gattggaaac ttttgtccga aatgtgttgg aggcgatcga tgcctccacg acgatttccc
   117841 cgccagcgcg gaatttcaca gcattctcta tcagctcatt ggtcagatag ccgacattgt
   117901 gacgcacctc cttgtagacg acgcgagacg ttttgtagcg cagggcagcg aactcggcca
   117961 caaaatcgga ggtcatcgcg caatgtttcc acccgagatc gagcgggccg tcgaagagac
   118021 ggagtttcgt cacattctcg cccggcccga cggcgagatc ctccagtcca tacaaggtcg
   118081 tcatccgctc acctgtgtct catcaccacc agagtgatat cgtcgtgaat tttctgggtg
   118141 cctatatgtg tcattaaatc ctctataatg ccggacttga cctcctcagc gctgctgcca
   118201 tagcgacagc gcgcgctttc gcagagcctt tcgatgccga agagctcacc gcttccgctc
   118261 tccgcctccg tcacgccatc ggtatggagg acgatcatat cgccgctgcc gaaggagatt
   118321 tcgcgcgttg cgacgaatgg agagatatca ggctccaagc cgatgggaag tccgagatcg
   118381 agggtgtcga tccgctccac cttttcgata tctctgatga cgatcaactc ctcgtgctgg
   118441 ccagaaagga tcagccttgc gccgtcatag tcgagaaatg caagggagag gtgcttgttg
   118501 gtgctggtcc tgaccagatt cttgtagatt gcccggttga cgcggttgag gaattgcgcc
   118561 ggctccatct cgcccacttc ctgcaagcca cgggccacgg attgaaccat cagcatcagc
   118621 acgccgctct cgagaccgtg cccggtcaca tcgccaattc caatcttcaa tcggtttccg
   118681 tccctgagaa cgtcgtagta gtcgcctcca acctcgtcgg cgggccgcat ataagcggcg
   118741 atttcgagct cggcgatttc ttcgagttcg ccggccttag gcagaaccat catctggata
   118801 tgtcgggcga ctgcgagttc cgcgcccagg cgcaagtttt cgctgcgcaa ctgctggttc
   118861 agagctgaga tctggaggtt cgcctcttcg atctccttcg tcctgtcctc gaccagctgc
   118921 tcgaggttct ctgtgtgaaa gctgatctct tcggccatac gattgaaggc tgcgccggcc
   118981 tcgccgacct cgtcgcgcgt cggaatgtcg acccttactg aatagtcctt ggcctcaatg
   119041 cgcttggcgg cattggcgag cgcgcttatg ccgccggtga tgcgcttgga aattgcgaat
   119101 acggcggcga tgacgaagaa gagggatacg agaagcgcga ggacctgata gatcaggatt
   119161 ctgttcgtcg ccttcgagat cccggcctgg gcggcgaaaa gcgaagcgta gatttcccgc
   119221 tccggcacgg cgattccgag caacatggct tcgcggctga ccgggcccga cgcccagagg
   119281 ttggttggct gcaagtgttt taggacgacc aggtacggca ccctctcgcc gttctcctcg
   119341 agcagtatgt gcttgagcag tccgtcctct tccaggggca actgcgcaat cgccggctga
   119401 atgctccgtc gcaaggagcg atccagtcct gtcacgccgc cgctggcggc agcgttcgac
   119461 gcccgcaggc caataacctt ttctccgacc ggattaatgg caacaacgtt gccgtccgac
   119521 atcgtcagga aaccgaaacc ggtttccgcc actttgacgt tctcgacgat ctcggccagt
   119581 tggtcgagcg tgatatcggt gccggcagcg cctagcaccc ggctgcggtc gcgcgaccat
   119641 agcggctgga agaaactgac gatgagcttg ccggttatcg cgtcggtata gggcgccgtc
   119701 tgggtaatgt cgtcattcac aggacgtgac tccggctcac gcgcccattg ctcccaggat
   119761 tcgtaaagac ccggaaagaa aaaagaccag aactccgccg cattgtgtcc cggatacagt
   119821 ttgtcgaaag tctgagcctg atccgtatag ggtgccgtcc tgaagatcgg ccgctccttt
   119881 gggccgatgt agtacatctg cagcttcgac tggccattcg ccagaaggct cggcgcgacg
   119941 aggtccagga ccgcgctgtt ctcgatgtcg gtctgcacat cgggaagcgg aaagtgattt
   120001 tgatcgagaa gataccccca gacgctgacg accgacggcg gacctggcag attttgagcc
   120061 cacccgcctt tctcgtcgta ggcaaccgcc acggttcccg gcgcaccacg cgccattgct
   120121 tcccctattt gcgattttcg caccggccgg tcgatttgct cctggagaac ccccgccagt
   120181 gtgcctacat ccgaatgaac ctggttgagc agaagattga cgcgggcggc cgtcgtttcc
   120241 gcataggagc ggatataatc ctggttcgcc tcctccaggc cccgcccgac ttccgctgct
   120301 gcatcgcgcg agagcctttg tacattccag agcgcaagac cgccggtgac gagcagatcg
   120361 aacagcacgg cgcctccgac gaccagaacg aacttggcgc ggaacgaacg caagcccaaa
   120421 cgagcggtgt tttcgcccat cacgctcata gcggcttgcg tccagaagcg gcccagatcg
   120481 gccaaccggc gtaaccctta ggatggaggg ccgcgaatat gtggtcccgg aagccttggc
   120541 ggaagcgctc tatgaattcg ggggggtcgc ctcgcttcac ggccatttca ccggcataga
   120601 cgttctccca ggcagcgatg atatctgcaa agtcctgggg atctccgtcg agattggtga
   120661 ccataaagga ttcgacgaga atatcgtcga aaccggcgtc gacaaggtag cgcttgctct
   120721 ttggcccgag ctccacatcc atctcgaaat gactgaacag cctcgcgact tcattgtacg
   120781 tccattgaat gctctgcgag cgcggttcgc cgagacagtg cgaatttttc tcgttggtaa
   120841 tgtatacccg cccgcccggc ttgcaaattc ggaagagctc tttcagaagc atgtccggct
   120901 gattgaatat ctgcagtgag tgccggcacg tgacgaagtc gaactggttg tcctcgagca
   120961 gcatctcgga ggcatcgcca taggtgtatt cgatatcggt tacgccgaag ccggacgcca
   121021 cgtcgcgcgc ataggcgagg ctcgctttcg aatgatcgag agcaacgatg cgcgccggct
   121081 ggaactcttt tcgggcgagc atggcgaaat cgccgatgcc gcaacatatg tctgccatcg
   121141 ccatgcccgg acgcaagccg tgacgcggga ggatggcacg ctcgtggcgc cacgtcattt
   121201 tcgtttgggt gcgcaggatc ggaataaagc tggtgttttc gacgaagctt tgcccgggat
   121261 agaacttcga gtcgtagacc tcgacagtca cttgcggctc gatcctgttc aagtgagcga
   121321 acatacgctc ggtccagccc acgacgctgg aggtcacgac gacaaagcga atgtccgatc
   121381 tcgtacgaca ggaatcgaga agaacgcgcg cgaaagcgtg gtaagccgtg ttgttcatct
   121441 gtacgaggcg cttgacgttg atgtagagaa cgccccgcac ctcttcgatt gcgcctttca
   121501 gcatggatat gattgcggcg atttcgtcgg ccgagcgcgg ccgcaccacc ccggaaagag
   121561 caaactcctg gctgttcggg tcgaattcgg ccttgaaggg cactgcaagc gctgtcgtat
   121621 tcaccgcaca actccttcaa gaggcagatc cacgacaagc gtgatcgatg gcggatcgct
   121681 ttcgccgagt cgaacgtccg cgtcgaaatt gatcgagagg tccagaagaa cagcctcgcg
   121741 actgggcgcg agatcggtgg cgatggaatc gaggtagcgc gcatgagcgt cgccgtcgcg
   121801 ggtcttcgcc accgcctcgc catagaactg cctctgaccg ggcggacagg ggaaagtcaa
   121861 ttcgacccgt tcggtcggac ccctgcgata gaccgcacag ccgatccggc catcgggtga
   121921 gccgccgcgg aacgaaacct ccaggagttc gttcagggcg gatgaaaaga aattcgagtg
   121981 gcgaacggga tccgtacgat tgtgacttat catccgagcc atgaagctcg acagctgatc
   122041 gcaatggttc caatcggaaa gaaaggcgcc catctccatc tcgaattgga gcaagggctc
   122101 gtaagcggcc tccgtgcggt gattttcggc tccgtgcatg cagcttctcc cttacgcaaa
   122161 aacgcgacgc ttgcttcaaa atccgttcga aaaaccggca ttcacccgct catattcgtt
   122221 gaaggcctgt ggcaggagtg gcagaggctt tgcggagaaa gtcgcctatc gcgtccgcag
   122281 ccatgggcgc ccctagaaaa tatccctgca accgatcgca gccttctttc tggagccagg
   122341 ctgcctgccc cgcggtctcg accccttcgg cagtgacatt catgccgaga ccatgagcga
   122401 gcgcgatgat ggagcggacg atcgtctggc ccttctcatt cctctcgaga tccttgatga
   122461 aatactgatc gatcttgatc gtgtcgaagg gaaaattctt cagataactc agcgacgagt
   122521 agtaggtacc gaaatcgtcg agcgatattt gcacacccag gacgttcaat gtgttaagcg
   122581 tatcgagatt gttgatcgta cgttccagca gcaccgactc ggtaatttcc agctcgaggc
   122641 gatctgctcg catcccgacc aggtcaagcg tctgggccac acgatccgta agcccctcgt
   122701 gaaggaactc cgccggcgat aagttgaccg cgagcgtgaa gtgggacggc cagtccatcg
   122761 ctgtccggca cgcccgctcg agaagccacc ggccgatgtc gctcatcagg ccgtcggctt
   122821 ccgccattgg aatgaagacg ttcggcggga tagtgccgac cagcgggtga cgccaacgca
   122881 agagtgcttc gaagccggcg accgacgacg atggtttcac caatggctgg tattcgagga
   122941 agaactgccc ctcctggagg gcggtgcgca ggctgcgccg cagcatttcc ctctgttcga
   123001 ggacgacgag catggagcgg gtaaacgtgc ttgagcggcc ccgaccgtcc ttctttgctg
   123061 cataaagcgc gatatcggca gctttcataa gctgctcgac ttcgttgccg tcttccggag
   123121 cgactgcaat tccgacgctt gccccaacaa aaacgttgat gccctctacc ataaaaggtt
   123181 ctttgaacgc gttgatcaat gcgtctgcaa ggcgctcggc ctcgctgggc tgatcggacc
   123241 tccattgaat gacagcgaac tcgtccccgg ccaaacggta cgcgaactcc ctatccctca
   123301 gaatgctcct gatccgatcc gccgccattt tgagaactgc atcgcctgcc ccgtggccca
   123361 atgtatcgtt gatcggcttg aagtcatcga gatcgatctg catgagcgcc acttgcgcac
   123421 cgttcggtac tggcaacgcg ccgcgcagct gatcgctgaa ctgacgccgg ttgggcaatc
   123481 cggtcagaac gtcatgggtc gcctgatgca ggagtagcgc acgatcgctc tcgctctgcc
   123541 tgaacgtctc gcgatacatg gcactgcttt cagcttcgac gactccgacg ccgctcctac
   123601 tgcggaaaat gaggagcgtg cgccggggcc cggccgatgc atgtgcgatc tcgacggttc
   123661 tcggcaatcc ggtcgcgacc acgaactcga cagcggactt cgcacccggc gccagtagtt
   123721 caggataaat gtgccaaagg gacgtctcta tgagggactc gacgacatat gcttctctgt
   123781 gccttggcgt gcattcgatg agttgaaaat tttcgtcgta aagcgagacg acttcgtcaa
   123841 aatcggcgaa aaatccagaa tcgacggaag gtgaaccagg cagtgtcgta tcgccgtccg
   123901 gcatcctcgc cctttccttc catttgtttg acccgagcag gcccctccgg actaagctcg
   123961 ctaatatcga ttcatgtcaa ttctcatttc caaccctgcc ccagcttgaa attatcgcgg
   124021 aacgtgtcgc cgtcaatggc gcacgaccga gagattagtt cgcgcgaacc cggcggaatg
   124081 atggctgatc ataaatcccg ggggcatacg ccccagcgac cgatccacaa ggcgaaggat
   124141 caagtggccg cggctgccag tccgtaggtc ccgtgcgaga gagcccgctc gatgccgcgc
   124201 aattcggcaa gacccttcag gcgaccgatg gccggatagc ccggctgggc cccgcgggaa
   124261 aggtcgtcga gaatctcctg cccgtgatcc ggccgcatcg ggattctgtg gtcggcccgt
   124321 ccggctgcgc gccgcagctg ctcctccctg agcaattcgg caatgaccgc caccatgtcc
   124381 gtattgccct ccagatgctc gtcctcatag aaagagcagg gtgttctctc ctcctcgcga
   124441 aggacgttgc gcagatgtac gaaatgaatg cgggaggcga aacggcggac catggccggc
   124501 aggtcgttgg cggcaagggc cccgagagag cccgtgcaga aggtgacgcc attggccgga
   124561 ctatcgacct cccgcagcat gtgagcatag tcttcggcat tcgaaagaat gcgcggcagg
   124621 ccgagcagcg cccatggcgg atcgtctgga tgggcacaga tgttgattcc cacgcgttct
   124681 gccaccggcg tcacctccgt gaggaactcc accaggtgac gttgcaactt ctcacggctg
   124741 attccgtcat agctgcgcag atgatcgcga agctgcggca ggctgtaacc gtcggctgag
   124801 ccgggaagcc cggccccgat gttgcgggag agcgcaaggc gccgctcctc cggcatttcg
   124861 cgaaaccgcc gttcggtttc ctcgcgcgtc gccgcgtcgt agtcctcgtg ggcgcccggc
   124921 cgctcgagga gatgtatgtc gaaggctgcg aaatcgatcc ggtcgaagcg catcgccttg
   124981 gcgccgtggc gcgccgtcca gcgcaggtcg gtgcgggtcc agtcgaggac cggcatgaaa
   125041 ttgtagcaga cggtacggat cccggcggat gacaggcgtc gcaacgtttc ctgccaattg
   125101 gcaatgtgct cccgccaggg gccggtttgt gtcttgatgc actcggaaac gggaacgctc
   125161 tccaccactt cccactccag tccacctgcg cggacctcct cctgacgctt gccgatctca
   125221 tcaacaggcc agacgtcgcc tgtcgggata tgatgcagcg cgctgacgat gccctgcgcg
   125281 ccggcttgcg ctgcatcttg aacgctcacc cggtccaccg gcccgaacca acgccatgta
   125341 tgtcgcatgt gaactcctca ggaaagaaat gtcagctgca ccttgcatgc agcagatcga
   125401 tcgccggcct gctcgaaggc tcgaaccgcc tcctcgaccg gaaactggtg ggaaatgatc
   125461 ggtcggacat caatccggcg atcggcgatc agcgcaaccg caagagcgaa ctcctgatcg
   125521 aatcgttggg atccgacgag acgcaattcc ttgccgacca gcgcatggag cgggagcttg
   125581 acatcgcccg tcactccgac ctgcacgatc atgccgcgcg gccggaccgc agcgaccgcg
   125641 ctgcgcagcg ccggctcggc ggccgagcac tcgaaagcca gatgaaactg gcccttgtcg
   125701 gtctcgtacg gggcaagccc ggccggatca cggccgatat tgatggtcct ggtcgcgccc
   125761 atggccatcg ccctgtcgag cgccgcatcg gccaaatccg ttacgacgac ctcatcggcg
   125821 cccccatggc gaactgccgc caccacaagg gcgccgatcg gccccgctcc ggtgaccagt
   125881 atcttctttc gcctgacatc gccggcctgg gcgagcgcat gaagacagac cgcgagcggt
   125941 tcggcgcagg ccgcctcacc ggcgccgaca agggtgcccg cgggatgaca ttggcgtgcc
   126001 ggaaccacca gccagtcacg gaacatgcct tgcgtatgag gaagacgcat cgcgctgccc
   126061 aggaagcgca tattgagaca gtgaacggca agaccgtcgc cgcagaagcg gcaggcgcca
   126121 caaggctggc tcggattgac ggcaaccaga tcaccgacgt caaggccgga gacatcgccg
   126181 ccgaaagccc caactcgacc tgaggcctcg tggccgggta tgatcggctc acgcacccgg
   126241 acggggccga atcccccgtc ctggtaataa tgaagatcgg agccgcatat gccgccggcg
   126301 gccatcttca acagcacctc gccgtggccc ggtgcgggaa cctcggccag ttccacccgg
   126361 agatcgcgtt ggccgtaaag ccgggcaaga cgcgtgtgca tgagtgctcc ttgcatcagc
   126421 ggatcaggcc caccgtctgc ggcagccaga gcacgacagc gggcacgaag gtgatcagaa
   126481 tgagagcgat gaacagcggc acgagccatg gcaggattgc catcgtcgtc cgctcgaccg
   126541 agagcttcgc cacccgcgaa agcacgaaaa ggaccatacc aaggggcggg tgaagcagac
   126601 cgatcatcag attgagcgtc atgatcaggc cgaaatgcac cgggtctatg ccgaactgag
   126661 cggtcagcgg cagcaggatc ggcaccaata tggtgatcgc ggcaatcgtg tcgaggaagc
   126721 agccgacgaa cagcatcaac aggttcacca ggatcaggaa gacccatttg ttgtcggtga
   126781 tcgtcaggat cgcgccggag agcatctgcg cggcctggct gactgtcagg agccatgcga
   126841 agatcgacgc ggccgtgacg atgaagagca ctgacgcggt cgtttcgatc gtgtcgaatg
   126901 tcgcccgggc gagcgtcgac atcgtcatgg tccggtatcg caccagcccg agaaacagcg
   126961 accagatcac ggccgcgacg gcggcctccg ttggcgtgaa ccaccccatg gtcatgccgc
   127021 cgatcagaat aatgggcgtc atcagcgcca tgacggcgga gaagtcgaag taccagtcga
   127081 gagcgagcag aaccaccagc gcgatcccga ccgcaaggtt cattgacagc ccggccgaca
   127141 tcagggcgta gacgagaagc ggcactgcaa gcacgacgac gacctcgagc gaggccgaaa
   127201 gcagccgctt catctcgaac ggcgtgtccg agccccaacc gcgcttatag gcaaagatcg
   127261 ccacggtcag catcatcagc accgtcatca ccacgcccgg cacgacaccc gccatgaaaa
   127321 gcgccccgat cgagacattc gccatcatgc cgtagatgac aaagggcagt gacggcggga
   127381 aaatgggtcc gagcgtcgcg gatgccgcgg tgacgccgac cgccgcctcc accggatagc
   127441 cgtgatcctt cattgccttg atctcgatcg tgcctatgcc ggcagcatcc gcaagcgcgg
   127501 tgcccgacat gcccgagaag atcaccgagc cgacgatgtt gacctgggcc agcccaccct
   127561 tcatccagcc gacgagagcc acggcgaagg aatagatgcg cccggtgacg ccggcggaat
   127621 tcataagatt tccggcgaga atgaaaaacg gcaccgcaag cagcggaaag ctctcgacgc
   127681 ctgcgatcat ccgctgcgct gcgatgatgt cgggcgcgac attgtagaag accagataga
   127741 gaaccgacgc cgaagccatg gagatagcca cgggaacgcc gaccagcatc aggaagagaa
   127801 aggaaacgac gagcagaagc atggcattca gtcctcgacc ttgtggaatt cctcgggctt
   127861 ttcgagaacc gaatagccgc ggcgttgatt ggcgacgaag acctggatcg agcggatcag
   127921 catcagcacg aagcctgcca gcacgccgta gaaaacgata ttgcgcggca ggttgacggt
   127981 gatcatacgc tcatgggcga cgatcgccac gtagcgccac atcagccagc aggcatagcc
   128041 gaagaagacg atgcgcacga gatcgacgaa gatcgccagg ccccgggcga cggttgccgg
   128101 cagataatga tagagcacgt cgacctggat atggcgcgac acgcgcacgc acatggcgga
   128161 gcccaggaac accacgccga tcaggcagtt cgtggcgatc tcctccgtcc aggcatagga
   128221 gtcgttgagc acgtagcgcg tgaagaactg caggaacacg catccggtca tcagccagaa
   128281 aacggcgagc gttacccaat cctcgaagga atagttggag aggtccgccg agggcggggc
   128341 ttcctcgaaa gcatgggcga tttcttcggg cgtcgtttgc aggtggactt cctgagacat
   128401 ggcatcatcc ggcattttag atggaacggg acgtcggccc gccttgcggg caggccgacg
   128461 ggtgcggttc acttgacggc gcggatggcc tcccagtctt ccttgacgta gccgaaatcc
   128521 tcgagcgcga ccttctcatt gacggttttt tcgaaatcgg ccctgtcgac ctcggttact
   128581 tcgataccgc gttccttgaa ggtcgctaca agttccttct cacgctcctc gatgatcttg
   128641 gtggcgcgct cggccgcctc ctgcataacc tcggtaaaga tctgcttgtc ggcatcggag
   128701 agctgtgacc agaggttctt cgaaacgacc gtgttcaggt gatcgacgat gtggccggtc
   128761 agcacgatat gcttctgcac ttcgaagaac ttcttcgcct ctatcgtcgt cagcggattt
   128821 tcctgcgctt cgaccgttcc gttctggagt gcgagataga cctcggcaaa agcgatcggc
   128881 gttgtgttgg caccgcaggc ccgcggcatg gcgagatagg ccggcacgtc cggaacgcgc
   128941 atcttcaggc cctgcatgtc ggcgcatttg gtaatcggcc tgttcgatgt ggtgtgacgc
   129001 gtcccgtaat aggtgacggc ggtgatgtgg ttgcccgagg cttcctcata tcctgcggca
   129061 aggcgcttga agacatcgct cttggtgtag gcgatcatat gggccgggtc gcggaagata
   129121 tagggaaaat aggtgacgcc gatgggcgca tgatcgcgcg cggcgaagct cgatcctgaa
   129181 atgatgatgt cgacggtgcc gagcttcagg ccttgattga tatcggcttc cttgccgagc
   129241 tgcgacgccg ggaagacatc gatcttgtag cgcccctcgg tgcgtttggc gatctcttcc
   129301 gccgcccaga cggactcggt atggaacggc tccgacgttt cgtagacatg ggcccatttg
   129361 agcgccgtct gggcatgggc cgataaggcc gatgccagga tggtcgcggt ggcaccgatt
   129421 agcgtcaaca gtctgatcgt catcttgatc ctcctcccaa ttgaagtcgc tgtgttgatt
   129481 accgcccgac gcgcctccac gcggcgggta tcgtgctgtc ggcggcctcc tcttcgaagc
   129541 tggccgacag gcgaatctgt gattggtcga gatgtgcccg catcgcggcg cgcgctgcgc
   129601 ccggatcgcc cgcggcgatg gcattgcgga tgacgcgatg ctcctccatc gccgcccgcc
   129661 aggtatcggt attttcgaaa tagcttgcga gcttttcgaa atagggcgtc atgcgcatgt
   129721 cgtggatgct gccgacgaaa cggttcagcg tcgcattggc gatgatgctc gaaacgacga
   129781 catgaaattc ccgatcgatc gccagcgcaa gccggcgatc ctcgagggcg gccgccatcc
   129841 gggcgagatt gtcgtccaga acggcgatat gttcgggccg cgccagccgc gccgcctcct
   129901 cggcgattgc gcattcgacg acagccctcg cccgcagcaa ttcgaaagga ccctcgaaat
   129961 cttcgggcgg cccatccgcc gccggcgccg gccgcgcggt gacatagatc cccgacccca
   130021 tccggatgtc gatgaagccc tccacctcca gcacgatcag cgcttcacga atggtcggcc
   130081 gcgaaacccc gaacatctgc gccagctcgc gctccgccgg aagccgcgac ccatgcgcca
   130141 gctcgccccg ttcgatcagg gcccgcatct gatccgccac ctgtctatag agacgacgcg
   130201 attccacggc agagaacatc atgatccccg ttgaggcgac cggctgccag gtggccaagt
   130261 ggtcatacca attgcggtac aatacccatg cttgcggttg tgtcaacatc cgatcggccg
   130321 cggcgagcga agcgaccata aggcgtcctc tctccgcgcg cctgaaacaa cctcgcgctg
   130381 atttcgcatc gacccgtaaa caaagatgcc cggcactgaa tggccgggca gttggcaggg
   130441 aattggctgt ccctgcggga aagtgagact cgcgacgcat ggatccaccg gccacgacgc
   130501 ctggcggaat gtcgacccga gcggcggcta ccgcgcgagc gcgccggacg ggacgcccct
   130561 gtcggcctcg cgcttgatct gccggatcga gaccttcatc cagatcatgg agacggctac
   130621 gatgacgaag agcagcatga agcagctcga ccagagaccg gttacatcct tgagatagcc
   130681 gaaagcgatc ggcaggacga agccgccgag gccgcccacc atgccgacga ccccgccgac
   130741 agcaccgaca tgggtgggat aatacacggg tatatgcttg tagaccgccg ctttgccgag
   130801 gctcatgacg aagccgagca cgaaagtgac gaagacgaag acgagcggcg tcaccatgat
   130861 cggcatcgca ccgctcgccg agccggcggg taccgacagg atggccgttg cgacggcaga
   130921 taccgcgaac atggcataca tgactttgcg ggcgcccagc ttgtccgaca gggcgcctcc
   130981 ataggcccga aagatgcttc ccggaatgga gtacgcggct gcgatcatgc cagccgtctc
   131041 gatgttgaaa ccgtagacgc ccacgaggta gcgcggcagc cagagcgcaa gggcgacgaa
   131101 gccgccgaag gcaaagaaat aatagagcga aaagcgccag acctggacat tcttgagagg
   131161 ctcgaattca ctaagcaggc tcttgcgcgc aacggcaccc tggcggcggg cgcgaaattg
   131221 cggatcgtct tcggtcgaga accagaagat aatggctgtg acggccagaa cggcagccca
   131281 gatctcggcg accgcctgcc agccgaaagc gacgagaacg aaaggcgcca ggaatttcgt
   131341 cactgccgcg ccgacattgc cggcgccgaa gatgccgagc gccgtgccct gcttctcagg
   131401 cggaaagaag ggcgagacat aagcgactcc tacggcaaaa gaacctcccg caagaccgac
   131461 gccaaggccc gcgaggagca tctgcggata ggtcgttgcg tagccgagaa gaaaggtcgc
   131521 aagcgctgcc gccagcatgg tgagggtgta gacgagccgg ccgccatacc gggttgtcca
   131581 gatgccgaga acgatgcgca cgagcgagcc ggtcaggatc ggcatgccga tcagcagccc
   131641 gaactcggct tcgctgaggc cgagatcctc cttgatacgc acgccgatga tggaaaaaat
   131701 ggtccagatt gcgaaacaga tcgtaaatgc gcccgtcgag gcccacagag cgcgtgccga
   131761 tgcgcccttt aaggtcgact gtgtctggtg aagagcggac atgatatctc cctgcgcagt
   131821 gatttcgcgc gttgtgtgcc gtcgatcatg ggaacagccg cgagcacggt ccgcgctcat
   131881 cgaaacgagc gcaccgaccc tctccagcaa ccttgctcat ggcgcgcgac attgggcgcc
   131941 acccggtggt ttgctcgggc tcgaagttat gaatgcaaac ggcgtgccag tccgggcact
   132001 ccggataatc gcccgtgatt caaggtatta tccggcgtcg gctttcgaag cttgggaaaa
   132061 gcttgttcaa attttagccc gccagggatg ccctgcccaa ttaccgggca tgacgggcat
   132121 gccgtcccga cccccgtcat tcctgcgctc gtcacaggaa tcctgtgtgt cgaaactgtg
   132181 cttatatggg tgcgggcgga aggccgtcgg aatcctggtc tttaaagacc gtgtgctggc
   132241 tctggtcctc cgcccgcttc gaatccctaa cctgaacagt tgacggaggc cgtcacagcg
   132301 gacctcgcat cacaggataa ggcagtccca tgatacatcc tgatgtcatc ggatgcgata
   132361 ttgcaaaagc gcatctagat tttttcgaca gcggccttga gcgccatttc cgtatcgaca
   132421 acactccggc cgcaatttcc gcgtggctcg acggccttga tggcagaggc gttcatatcg
   132481 tctttgaggc gaccgggcgt tacgatcggc agttgcgcat agccctggag acccgggagt
   132541 tgccctattc ccgcgtcaat cctgcccgcg cccgcgactt tgccaaggcg atcggccttc
   132601 ttgccaagac ggatgcgatc gatgcacgtc tgcttgcccg gatgggtcaa agcctgccac
   132661 tctcaactca ggcgcctgac gatcccgccc gccacgtgct cgcccgcctt cacacgcggc
   132721 gtgaccagct cgtggccatg cgccagcaag agcggacacg ccttcatgag accgagggga
   132781 tcgagcgtga cagtgctgaa agccatatgg cttggctcga cgcggaggtt gcgcgcatcg
   132841 aaatggcatg ccgtgatgtt ctgaaggccg agaagacctt gcaagaacaa gaggcaaggc
   132901 tgcgttccat tcccggcatc ggccccgtgg ccgcattgac cctgatcgcg catatgccag
   132961 aactcggcaa tcgttcggcc aaggcgattg cagcccttgc cggtcttgcg cccttcaatg
   133021 tcgacagcgg cacgtcacgg ggaaagcggc atatacgcgg cggtcgcaag cggatacgtg
   133081 acgcgctcta catggcggcg ctcacagcca gccgtatgcc ccgtgctttt aagtcccatg
   133141 ctgaccaaat gaaggaggca ggcaagccct tcaaggtccg tcatcattgc gcttgcccgc
   133201 aaattgctcg ccatcgcaaa cgccatcatc agggacaaaa caaccttccg acgaaccacc
   133261 tgacaaacac agttgccagc cagaccaagt ccttgggctg aagagacgct tccagccgcg
   133321 ccgcagatga agcgtggaga ttgcagccct ccgataggct tccccggcaa cgcgcaccgg
   133381 ggtaggagct gctatacttc gactgccagc accgcgcagc agtcgcccgg cttgatcagc
   133441 ccgggattat gtctggccac gagaaggccg ttcatcctgg ctcggacctc caccggttcg
   133501 acacccgtgc gtccgatcgg atagacccgc gcaatcaccg cgtcgcgtgc gaccgcttcg
   133561 ccgaggtcga cgagaaactc gacgagccct tcatcctccg cgaaagcgaa acaatcgtcg
   133621 ctcggcatgt cgagccaccg ggtggatgcc gtctcgacct cgccctcgag gatcccggca
   133681 tgcttcagga cattcacaac accgcgtttt gcgatcgaag ctgtccgggc ggttgccgat
   133741 ccgccgcctc cgagctctgt ggtgacgaag atcttgccca tctcctcggc ggccgtgtcg
   133801 tacattccga ccgtatcgat ctccagcatc ttcatcgaat agggcgcccc gaatgcccga
   133861 acgaattcga aggccctttc ctcctgcgcc ttgtcaggca ggacatgagc cgcgcagaag
   133921 ggcaggaagt cgagcgtctt cccgcctgaa tgaaagtcga gcacgatgtc ggcgagcggc
   133981 agcaggacac gctggaagta gtccgcgatt ttttgggtga ccgtcccgtc gggcttgccc
   134041 ggaaagctgc ggttcatatt gcccctgtcg atcggcgacg tccgcgtctg cgcctggaag
   134101 gccgggtagt tcattgccgg aacgatgatc acccttccct cgacatcggc ggcatcgagc
   134161 ttgcgggcga gatcgaaaag cgcgatcggc ccttcatatt cgtcgccgtg attgccgccc
   134221 gtcaggaggg cggtcggccc cttcccgttc ttgaccacgc tgatcggaat catcaccgaa
   134281 ccccaggcgg aatcgtcgcg gctataggga aggcgcagga agccgtgctg gatgccatcc
   134341 gcctcgaaat cgacggtggc gctgatcggc gatggccgca agtgatgctc cctcatccgt
   134401 tcagtccttg accatcagct tgcgcggcac ggaggcaagg cactcgacgc cgctctcggt
   134461 gatgagaatg ctttcggtcg tctcgaaacc catgtcctcg agccagaggc ccgtcatgaa
   134521 gtggaaagtc attcccggct tcagttccgt cctgtcgccc gagcgcaggc tcatcgtgcg
   134581 ctcgccccag tccggcggat aggaaagacc gatgggatag ccggtacggt tgtctttgac
   134641 gatcccgtat ttcttcaaca cggagaagaa cgcgttcgcg atgtcctcac aggtattgcc
   134701 gggcttggcg actgcgagcc ccgcctccat gccttcgaga gtcgccttct cggcgtcgag
   134761 gaaggcctgg gtcggcttgc ccaggaacac cgtgcgcgac agcggcaggt gatagcgatt
   134821 gtagcagccg gcgatctcga aaaaggtgcc ctcgcctcgc ttcataggcc ggtcgtccca
   134881 ggtgagatgc ggcgctgaag cctcgacgcc ggaagggaga agcggcacga ttgccggata
   134941 gtcgccgccg atgccatcaa cgccccgcgt gcccgcatcg tagatttccg ccaccagatc
   135001 gcatttgcgc atgcccactt cgatcttgtc gaagatgcgc tgatgcatgg cttcgacaat
   135061 gcgggcggcg ttgcgcatat atttgatttc cgtctcgctt ttgacggcac gctgccagtt
   135121 caccagcgcc gtcgtgtcga cgaaacgcgc attggggagg cgcttctgca gcgacgcaaa
   135181 cgcagcggcc gagaaccagt aattgtccat ttctacaccg atgcggagcg aaccgaaccc
   135241 gcggtcggcg aggatacccg agagatagtc catggggtga cgttcggtcg actgcacgta
   135301 gtgatcgggg tagccgatga tgttctcgtg tttgagatag gcggtaaact tcgccccatt
   135361 ggcatcctgg ccgcggccga accagatcgg ttcgcccgaa ggcggtacga tgaccgcctg
   135421 atgtacgtag aaggaccagc cgtcatagcc tgtgagccag gccatgtttg aggggtcgct
   135481 cacgatcagg aggtcgacgc ctttcgcctc catggccttt cgggtcttcg cgagccgcgc
   135541 ttcatattcc tcaagggaga atttgaggtt gggttgggtc atgtcttttc cctcgttctt
   135601 ccggcctcgt ctttggcaat gccggtgtca gctgtcgaat gtcgtacttg cgtccgccgt
   135661 gtttgcccgc gcgaaggcga gcgtggcgat ggcggtgtcc tggatgccgg tgccggtcag
   135721 gtcggcaata gtgatctcct cggcccgcgt gcgaccgggc ttcatcccgg cgatcacctg
   135781 gccaagttcc gcaaattcgg cctccgccgg cacgagacgg gcggcgatcg cgtgatgcag
   135841 ttcgccgagc cggcgggtct gcctgaggct gtcggcgaca taggtggcgc gggcgaaggc
   135901 atgcgggtcg agctcgttct tgtgctcggt gtccgacccc atgaccgtga cgtgctgccc
   135961 cggctgaagc cattcggcct tgaggaccgg cgtttctgac ggcgtggtcg tcacgatgat
   136021 gtcggccccg ctgacggcgg ctacgggatc gacgacggcg ctgacggcaa agccgagctt
   136081 atcggtcatc tcacgcgccg ccgcttcggc cttgccggcg tcgcgagccc agatacgcgc
   136141 ctcccggatc ggccgcacga gggcaagtgc ttcgagctgc aatcctgcct gcatgccggc
   136201 gccgaaaacc gtggcgatcg aggcgtcttc ccgcgacaga tgcctggccg cgaccgcccc
   136261 agccgccgcc gtacgcacgt cggtaagata gccattgtcg agcagcagcg cctgcaccaa
   136321 tcctgtcttg ctggacagaa gcaccatcat gccgttggtg ctcggcagcc cgagcttcgg
   136381 gttgtcgaaa aagcccggac tgatcttgat cgcgaagccg tcgagacccg gcacgtaggc
   136441 cgtcttgacg tccacctcac cgcgatgctc cggtatgtcg agcctcagga tcggcggcat
   136501 cgccaccgct tttgtggcaa gcgcgtgaaa cgcctcctcg acgcaggcaa ccgcttcgcg
   136561 atcgagaggc acgatgctgc gcagttgcct ttcggtgagt atcttcatcc gtgtcatgcc
   136621 gcctccccgc gaaacggatc cgcttcgccg ttcatcacgc gcaggtgcag gtccatgtcg
   136681 acattgcggc ccgacaggat gatcgcgatc gggccgtcga tgtccctgat ctttccggca
   136741 agaagcgcgg cgatgccgac ggcgcccgcc ccttccacga tctcgcgctc ctcagcatag
   136801 gcatgacgca tgccggcagc gatttcatcc tccgtcagaa ggatgatctc gtcgaggagt
   136861 tcccggcaca tgcggaacgt gacgcgattg tccagcccta tgccgccgcc aagcgaatcc
   136921 gccaggctcg gatattcgtc gacgagcacc ggcccgccgg cagcgatgct cgcctgcatc
   136981 gccgcgccgc gctccatagt caacccgatg acgcgcgtcg ccggtttgcg cgccttgacg
   137041 gctgccgcca caccggcggc aagcccgcca cccgagaccg gcacaagtac cgtcgataca
   137101 tccggcatct gcgtaacgat ctcaagtccg agcgtcccct gccccgcaac gaccgccgca
   137161 ttgtcgaaag gtggcaccat cacgagacca ttttcggcga ccagccgttc gacttctacc
   137221 tgcgcctcgt cctgggaatt gcctattatc cgcacatggg cgccaaggcg cctgatttcg
   137281 gaaaccttgt tcagcggcac cagatgcgac atgcaaatcg tcgcgaccga gccctccgcc
   137341 ttggccgcat gggccagtgc ccggccatga ttgcccgtcg acgccgcgat tacgccgagt
   137401 gcccggtcgc cgggagaaag cgaaagcacc gcattggtcg cgccgcgcag cttgaagctg
   137461 ccggtcgtct ggtggtgctc gagcttgagg ccgaccggca caccaatgcg ttcactcaag
   137521 gatgccgagt ctaccagcgg cgtggtccgt acgcggccgg aaatgcgccg cgccgccgcc
   137581 tcgatgtcgt ctatcgtcac aggaagagaa acgctcacag tcgttctcct tcgagcggca
   137641 gctccatcag ccggccgaga tgcgggcgtg cttcctggtc gccgcaaaga cgcaggcagg
   137701 cccaggcggt ggcgtaattg ctgctgacga ccggcttccc gatcgcctgt tcgatttcgg
   137761 cgattttgac tgccgcgcgc acagcggtgc aggagatgaa gagcgcatcc gattccgctg
   137821 ctgcggcttc cttcgcgaag gccacgatct cctcgggccg gatccgcgcc atctcgcgat
   137881 cgtccgtgag acccaggcag gtaaacctgt cgatagcgaa tccacgctca gcgaaatagc
   137941 cggccatggg cctgctggtc tcgatcgtgt aaggggtaag aaccgaaatg ttcttggcgc
   138001 ccagagccct cagaccccgg accgaggcat cggtcggcgt gacgacggtc gcccccggct
   138061 tcgcggctgt tatcgccgca gccacctcct cgtctccaat gaccacggag gccgaggtac
   138121 aggaatacat gacgacgtcg agggtctcgt cgggcaggat cagggccgcg gcttcggtta
   138181 gcgacggctg cattgcccgc aggttctccg gcgtcaccgg attggcatag gggatacggg
   138241 tgacatagac cccgatccgg tccgatgcga ccatccgttg aaaatcgacc tccgtcgtat
   138301 gatcggtggc gaggatgacg agcccgatcc gtctattgac gggtcgggcg tcgagccgcg
   138361 ggctccgcga ggcaagcgat agcgcaacgg gggatttcat cagcgttgct ccacacggga
   138421 ataacgctct tccagccagc gcaggaacac gaccgagatc aggctcatga tcaggaagaa
   138481 tacgcccacc agcgtcatcg gctcgatata gcgatagttg ctgttggcga tgctcttggc
   138541 ctgattcatc agttcaagca cggtgatcgc cgacagcagc ggcgtctcct tgaacatggc
   138601 gatcaggtag tttgcgaggg cgggaatcat cggcgggatc gcctgcggca ggatgacgtg
   138661 gatccaggtc tggcgagcgg tcaggtttgt tgccttggcc gcttcccatt gtccgcgcgg
   138721 cacgttttca atgccggcac ggtaaacctc ggcggcatag gtgccgtagt gtattccgag
   138781 cccgatgacg ccggcgacca gagcaggcag gcggattccg acgtccggaa gcacgtagaa
   138841 gatgaagtag agctgcacga gcagcggcgt gccgcggatg aactcgacga tgaagctcgt
   138901 ggcgcgcgcg atcggcttcg gcgcagtcat ccgcaggatg gcgaagacaa ggccgatcac
   138961 cgcggcaacg accgcgccga gcgcggtggc aagaatcgtg atcttcagcc cctcgatgag
   139021 ggtcggcatg atctggcgga cgaattccca atcccattcc atgatcagac cctcacaccg
   139081 tcgaggccgc gactgacgcg cctctcgagc cagcgcatgc ccatcgagat cagccaggcc
   139141 atggcgaagt aaagcagcag gatggtcgcg aaggggatca gcgtgctgcc ggtttgggcg
   139201 cgcaccacct gagcctgaaa ggtcatgtcg gtgagcgaaa tcagagaaac caccgcagtt
   139261 cctttcaaga gctcgatggc attgttgccg aaggtcggca gcatcagcgg gagcgcttgg
   139321 ggcaggatga tgtggcgcat cgcctgaaaa cgcgtgagat tgagcgcgat gcaggcctca
   139381 cgctgctcgc ggccgatcgc tttcaccgct ccccgcacga cctcagcgcc ataggcgccg
   139441 acattcagcc cgagagcgag cacacctgcc tgcagcggcg tcagcgtgat gccggcaaaa
   139501 ggcaggacga aataagccca gaacagttgc acgaaaatcg aggtgccgcg gaagaattct
   139561 atatatgtgg tggcgagcgc acgaacggcc atgaaccggc tgagccgccc gagaccggcc
   139621 gcgaaagcca ccacgacggc cagcgccgag cccatgaggg tcagttgcac ggtcacccag
   139681 gcgccctgca ggatcaatcc gatatagccg gaccagtcga tcatcgtttc gttgttccag
   139741 tcagaatttg ggcctggttg ccgccgccca caccgccttc ccatcgcacg atgcgaacgg
   139801 aaggcggccg ggaaccccag ccggggctta tttcgcggcg cagagcttct cgcgggtggt
   139861 tgacattgca gccttggccg agaagccata gggctcgatg atcttcgcga attcgcccga
   139921 ttccttcagt ttggcgagct cgacatcgaa ggcgtcgcgg agcgcctcgt cgcccttctt
   139981 gaaggccgcg ccatcgcaat agaccggcgc accctcgacc ggcgcgacaa cctcgatatt
   140041 ggggtcgttc gccttggaga cgagatcgtt gatcgaaagg accggaagcg aatagacgtc
   140101 gatgcggccg tcctgcagca tcttcatccc gctctggcca tccggtacca cgatgacgcg
   140161 gtcgcgcggt acgcccgctt cgagcgccag cttctcctcg gtaccaccgc ccggcgcgcc
   140221 gatcttggcg tccggattgt cggcgatgtc cttgtagctc ttgagaccga gcggattgcc
   140281 tttcttcagc gcgaaggcct cggcatcgca gaggatcggc tcggaatagg cgacggcggc
   140341 gcagcgctcc ggcttcatga aaaggccggc ggtgatcgcg tcatggcggc cggcctgcaa
   140401 gcccgggatc atcgcgccat attcggaaat ggaggctacg acatcggcga cgccgagccg
   140461 cttgaagact tcgcgggcaa catccggtgc tgcaccggag accttgccgt cggctccgac
   140521 ggcggtaaag ggcggttcgt tggcaatggc aatgcgcgcg aagccctgtt ccttcagctc
   140581 atcgagcttg ttctcatctg ccgtggcagg cgtcgccgca gcaactgcca tcaatgccgt
   140641 ggcgcctgcc gccatcgcca tccaatctct cagtttcatc gttcccaact cctctgttct
   140701 ctcgatgttt tccttgaggc aatgccggcc gtaaggctta gacgcggtgc cctgccgcta
   140761 tgatcttgcg caggaatgtc tgtgtgcgtt cctgtttggg atgccggaaa atctcttcgg
   140821 gctttccctc ttccacgatc ttgccgcgat cgaagaaaag cacccggtcg gcgaaatcat
   140881 gggcaaagcc catctcgtgg gtgacgagca gcatcgtcat gtccgtctct gccgcgagtt
   140941 tgcgcatgac gttcaggacc tcctccacga gctcgggatc gagcgcggag gtgacctcgt
   141001 cgaaaagcat gatcttagga gagagcgcca gggcgcgagc aatcgcaacg cgctgcttct
   141061 gcccaccgga aagctgcgcc ggcatgctct tggccttgtc ggcgaggcca accatgtcga
   141121 gcagctccat cgcgcgtttc tgcgcatcag cgcgggccat gccctttgtc agcatcggcg
   141181 ccagggtcac gttgtcgaga acgcatttat ggggaaagag gttgaagtgc tggaagacca
   141241 tgccgatctt ctcgcgcatc ttgtggaggt gccgctcgtc ggcgggaacg aggttccccg
   141301 ccttcttcac atgatagagc tcttcgcctt cgacctgaat gaagccctcg ctgatcgtct
   141361 cgagcgtcat cagaatacgc aggatggtcg tcttgcccga acccgatgga ccgatgagcg
   141421 ccagcttctc gcccggcatc acctccatcg acaaaccgtc gagcacagtc agaggaccgt
   141481 atcgcttgac gatattgtcg atgcgaatga tcggctggga cattcacgcc tctcccttcg
   141541 agatttccga tgcgcttggc cgctgagcat tcaggcgccg ttcgttgatg tcctaacgat
   141601 gatccggttc caaaatcatg tcaatctcaa ttataatatc atgacaatta ttcggaatat
   141661 gcctaaaagc ggagcattcc cagtcaaatg acgagcaata atgcctccgg cttgccaagc
   141721 gccagggagg cgacaatgcc aagcccggac ctgagttcct gctcggtcgt cgagccgagc
   141781 gatattctga cggccggacg ccagccgctg tccgccgttc ggaaggatgc acccggtgcg
   141841 atcgccacgc cgcgcaggcg tgcctgagag acgaaggcgt cctccatatg accttcgggc
   141901 agcggcagcc agacatgcag gctctgcggg tgcgtgtgat gagcaagact tccgagcacc
   141961 tccttggcga tcacatggcg cgaggcgagc gcgcggcgct gccagttcac gagttcgatc
   142021 gccgtgccgt cgctcaccca ctgcgtcgcg atctccgcaa tcgccggagt cgccatccag
   142081 ttggaaacga gatgcctgtt ggcaaccgcg gccacataac ggtcgggggc caccaggtag
   142141 ccgatcctga ggccgggcac ggttatcttg gtgaagctcg tcacgtagag cgtacgctcc
   142201 ggagccaatg cggcgaccgg gggcaagcgc tcctcgacca ggggcccgag gatatcgttc
   142261 tcgatgatgg cgatgtcgtg ccgccgcgcc acctccgcca gcgccgcccg ccgctccgcg
   142321 ctcatcaggg tcgcggtcgg gttgatcacc gaaggctgca ggaagaccgc gcgaaccacg
   142381 cccttgcggc atgcctcgtc cagggcatcc ggaatcatgc cgtcgcggtc gatggcgatg
   142441 ccgttgaggt ggattccgag atagctcgaa agcggcacca gagtgtggtg actgatcgcc
   142501 tcggttgcga cggtcgagcc gggcggcgcc acgctcatca gcgccacggt catggccgaa
   142561 gtcgcaccgt tggtcagatt gatgttgagc ggagagacgt ccaggccgca gcgtaacagc
   142621 cattcagccg cgatgttgcg gtgccgcggg aagaccatgt tcggacgaaa ggaaagcgcc
   142681 gaacttgcag gcaggttttc ggcaagccag gcaaagccct gccgcatctt ctccagatgg
   142741 tattgctcgc agaccggctt gagaatcgaa agatcgatca attcgcccag acgctccggc
   142801 agatagggcg gctccggctc gcgcggccgc gtctgcacga aactgccacg cccgacctca
   142861 ccggagatca gcccgcgccg gatgagctcg tcataggcgc ggcttaccgt ctgaaccgag
   142921 agcttcagat cgtcggcaag cttgcggtgc gtcggcagcc ttgcaccgtt ctggagcctt
   142981 ccttcctgaa tggcgcgggc gaattgatcc gccagcgaaa gataggcagg gcggcgcaga
   143041 agtgtcgtgt cgggcgtcca atttgtcatg atttgaacag tgatcaaaat cagctcaatt
   143101 gacaatgcaa aagtgagcac ccaatgtcat ttcctgactt tgatatgacc agcaccgacg
   143161 gaaggacctg tttatgaagc tcgatgcgat cgacctgcgc attctcgagg cgatccaggc
   143221 cgatgggcgt atcaccaaat tggcacttgc cgagaaggcg ggcctgtcgc cgacgccctg
   143281 ctggatgcgg ctcagaaagc ttgagaaagc cggcatcgtc accggctatc acgcccgcgt
   143341 ggcactgagg cgggtggcac ctgtcgccag cgtcatgatg gagatcacgc tcggcaacca
   143401 ccggcaggcc gatttcgatc gtttcgagcg ggccattgcc gcgatccccg agatcgtcgc
   143461 ctgctggtcc gtcggcggcg gggtcgacta tatcctcaag atcatgacgg cggacatcga
   143521 cgcctaccag cgcttggtcg acgggcttct cgaaagaact cggcatcgat cgatatttca
   143581 cctacatcgt cacgaagacg gtcaaggacg agaccgtcct gccgctcggc tcgctgttgc
   143641 cgcaagcgtc ggctgggcag gattaggcga caccgggcgc agcccaggca acggcgctcg
   143701 agatagtcaa tctctccccc cattgccccc actttggtca aagtctctcc cctgccctgt
   143761 ccgtttggac aatctctctc cacaacggtg gcactcttct ctcaacagtc gaggagaacc
   143821 cttatgaccg ccatttttgc gcgcacagcc tttcacgatg cgttgaaaaa actgaacgac
   143881 cgccaattgc tgcgggagct tgcctatgtc ggcggccgct gggttgccgg acgggagggt
   143941 tccagccttg aggtgagcga tccggccagc ggcgcgtcac tcgccttcgt cgcctcgctc
   144001 gacgctgcac agacgtcgga agcgatcgac gcggcggaaa aagcgttcag ctcctggcgt
   144061 aacatgctgc cgcaagcacg cgctgcgatt ctgcgcaaat ggcacggcct catgctcgac
   144121 gcccgggagg atctcgctct tttgatgacc ctggagcaag gcaagccgct cgccgagtcg
   144181 cgcggcgaga tcgagtatgc ggcttcgttc atcgagtggt atgccgaaga gggcaagcgc
   144241 ctcaatgccg aaagcgtgac gagccatctg gccgatgccg aaatgatcgt gcgacgcgaa
   144301 gcactcggag tcgttggcat cgtcacgccc tggaacttcc cttccgcgat gatcacgcgc
   144361 aaggcggccg cggcccttgc tgcaggctgc accgtggtgg cgcacccctc gtccgagacg
   144421 cccctctcgg cgctcgctct ggccgaactc ggagagcggg ccgggcttcc ggctggcgtc
   144481 ttcaatgtcg tcaccggcaa ggcggcaacg atcgtcggac gaatgtgcga ggacgcacgg
   144541 gtgcgcgcca tgagcttcac cggctcgacc gaaatcggcc gcctgatcgc ctcgcaatgc
   144601 gcgccgacga tgaagcggct ggtgatggag ctcggcggtc atgcccccct tattgtcttc
   144661 gccgatgcga atgtcgaaaa ggctgccgat attgcgatag ccgcgaaatt cgccacttcc
   144721 ggccaggatt gccttgccgc caatcggatc tacgtcgaac ggcccgtgct caaggcattc
   144781 caggaagcct ttgccgcgcg gattgcccgt ttggaagtcg ggtccgggat ggaaccgggt
   144841 acggatatcg gaccgctcat gcacgaacgt gccgtcgcca aggtagagga acaagttgcg
   144901 gacgcattga aatcgggcgc caggctttcc gccggcggca agcgacacgc cgccgggccg
   144961 ctcttcttcc agccgaccct tctgacggat gtgccggacg acgcgctgat catgcgcgag
   145021 gagaccttcg gccctgttgc ggccatctcc gccttcgata gcgaagacga agtggtcgcg
   145081 cgggcgaacg acacggaata cgggcttgtc gcctatgtcg taaccgataa cggcgcccgc
   145141 cagatgcggc tcgcccgcgc cctcgaatac ggcatggtag cgatcaatcg ggtgaagatc
   145201 accggtgggc cgatcccctt cggtggctgg aagcaatcgg gcctcggccg cgaaggctcc
   145261 cgccacggca tggaggcttt caccgaactc aaatatctct gcatcgacac cgccgcctga
   145321 tcattgcatt tcgacaaaag tgcatagcgg tttgcatccg gcattgcgta aaacttgcgc
   145381 tagattcatg aaaggaaata ccatgctcga gaatagcaac gaactcactg cctgggaccg
   145441 cgaccacttc ttccatccct cgacccatat gggaatgcac gcgcgcggcg agaccccgac
   145501 ccgtgtgatc gggggcggcg aaggcgtcta cataaccgat atttccggca agcggagcct
   145561 cgatgccttt gcaggcctct actgcgtcaa tgtcggctac ggccgtcaga agatcgccga
   145621 tgcgattgcg gaacaggcga agaacctcgc ctattatcat gcctatgtgg gccacggcac
   145681 ggaggcctcg atccggcttt ccaaaatgat tatcgaccgg gcaccggaag gcatgtcgcg
   145741 cgtctatttc ggtctgtcag gttcggacgc caacgaaacc aacatcaagc tgatctggta
   145801 ctacaataac attcttggcc ggccggagaa gaagaagatc atctcgcgct ggcggggcta
   145861 tcacggctcg ggcgtgatga ccggctcgct gaccggtctt cacctcttcc acaatgcttt
   145921 cgatctgccg cgcgcgccga tcctgcacac cgaagcaccc tattatttcc gccgcccgga
   145981 ccgttcgatg agcgaggagc aattctcgca atattgcgcc gagaagctgg aggagatgat
   146041 cctcgcagag ggtcccgaca ccgttgccgc cttcatcggc gagccgatcc tcggcacggg
   146101 cgggatcgtg ccgccgccga aaggctactg ggagaagatc cagggcgttc ttcagaaata
   146161 cgatatcctc ctggttgccg atgaggtggt gacaggtttc ggccgtctcg gtaccatgtt
   146221 cggttccgac cactacggca tcaagccgga cctcatcacc atcgcgaagg ggttgacctc
   146281 ggcctacgcc ccgctgtccg gcacgatcgt cgccgacaag gtctggcagg tgctggtaaa
   146341 gggatcgaat gagctcggtg ccatcggcca tggctggact tattccgcgc atccgatctg
   146401 cgccgcagcc ggcattgcca atctcgagct gatcgacgaa ctcggcatcg tggagaatgc
   146461 cggtacgacg ggcgcctatt tccgcgaaga actgcagaag gctatcggcg atcaccgcaa
   146521 tgttggcgaa gtgcgcggcg acgggttgat ggcggcgatc gagttcgttg aggaccggga
   146581 cgaccgcgcc ttcttcgacc cgggccgcaa gatcgggccg caggtggcaa cagcgctcct
   146641 cgaacgcggc gtcatcggcc gtgccatgcc gcagggcgac attctcggct ttgcaccgcc
   146701 gctctgcttg acgcgtgatg aagccgacat cgtcgtcaag gcggcgaccg atgccatcca
   146761 gtccgtattc gaccgctgag gaggacgcat atgataggtt ccattcctga cgccatggcg
   146821 gcagtgcggc tgaccggcca tggcggattg gacaagctcg tctacagccg ggacgttcca
   146881 gtcccggctc cggccgcagg cgaggtgctg atcaaagtca ccgcctgcgg catgaacaat
   146941 accgacgtat gggtgcgcga aggcgcctat ggaacggaag acgacccgtc cgccgtctcg
   147001 acctggcgcc gccagggcaa taccctgacc ttcccgcgca tccagggtac ggacacggtc
   147061 gggcacatcg tggcggtcgg cgaaggtgtg gacgaggcac gcataggcga acgcgtcatg
   147121 gtcgatttct cgatctacaa ccgcgacgac gacagtcttg ccgacatcga ctatatgggc
   147181 catggccgcg atggcggcta tgccgagtat atggcgcttc cggcagaaaa cgctcacgtg
   147241 gtcgcaaccg acctgaccga catagagctt gccaccttct gctgtgccta tctcaccggc
   147301 gagcgcatgc tggaacgggc gcggcttgcc gccggcgaga ccgtgctcgt gaccggtgcc
   147361 tcgggaggcg tcggctcggc gatcattcag cttgcccgcg cgcgcggcgc cgttccgatc
   147421 gccgttgccg gaccgggcaa ggaagcagcg atgctcgaaa tcggcgccga agccgtggtg
   147481 acccgaggcc agggcaacct cgccgaggct gttgagacgg caggcggcgg ccggccgatc
   147541 gatgtggtcg ccgaccttgt gggcggcccc ctcttcaacg accttctgaa gatcctgcgc
   147601 ccggaaggcc gctataccac cgccggggcg atcgccgggc cggtcgtgca actcgatctc
   147661 aggacgatgt acctgaagca attggagctg cacggatcga gccagggcag ccgggccgat
   147721 ttcctccgcc tcgtccgcta tatcgaggag aagaagatcc ggccgctcgt cggcggcgtc
   147781 tatcgccttt cgcaattcca tcgggcgcag acagacttca tggcgaagaa cttcgtcggc
   147841 aagctcgtgg tcgtgcctga ttgagcggat gctgtcctct ttcccgtgac aaaaagcacg
   147901 ggaatgagga acttctcagg cgacctgctg gagatccgcc atcgcttcgg caattcgctg
   147961 cggggccctg ggacgcgcat acatccgctc aaaatatgcc ttgagattgg aaaagccgtc
   148021 gatcaacgca ttttcgttgc cccagtccag cacataagcc gtgacgcaat cggctatggt
   148081 catcctctcg ccgacaatga actcgcgccc gtccatgtgg cgttcgagca ctgctgccat
   148141 cgccaggaac tcttctcggg cgagcgccac atcttccggt aagcgcttgt tttcgggata
   148201 cagaaattcg tgcttggcta ttcgccagag gggctgttca agctcggtaa ccgcaaaaag
   148261 agtccaacga taagcctgcg cccgctcctt cagatccgtg ggcatcaagc ctttggcacc
   148321 atatttctcc gccagataca taacgatcgc ggcggattcc gtgaggatga agtcaccgtc
   148381 gaccagcacc ggaagcttgc cggcagggtt gaggcgcagg aagtccgggt gccgggcttc
   148441 gccacccaag atgttgacgg gtacgaactc gaactcggca tcgagttccc gcagggccca
   148501 aagcgcgcga agcgaacggg tcggacccaa tccatacagt ttcatcatct tggttctcct
   148561 gcttgctgtc caatcgttga aattgcgtag tcgctatcaa aggacgctgg cgggaccttc
   148621 gagccgacag gcggtcgcaa aaaatctggc gagccacgca ttggccgcgc gcctacaggc
   148681 ggcggccggc ggcgtcgaac caatgcaggc tttccggttc cgctgcgacc tcgagctcct
   148741 cgtcgattgc cgtgcgggaa cggccggcaa ctctgaagac gagcggctcg ccgttggtca
   148801 aagtaccgtg cacgtaactt tcggcgccga ccagctccac ggcaccgacg cgaacccggg
   148861 ctctgaaacg atcgcctccg gccgaaccat ccgcgagtgt gatgtcctcc ggccggatgc
   148921 cgattgtcgc aagccccggt ttcccgacca gcccccccgg aacggtccac gcagaatcgt
   148981 ggctcccgat atcgagcagg ttcatcgacg gtgaaccgat gaaggtcgcg acgaatgccg
   149041 tcgccggttt ctcgtagagc tcgatgggcg tccccacctg ctcgatcctg ccgccgttca
   149101 gaacgacgag gcgatcggcg agcgtcatcg cctcgagctg gtcgtgcgtg acatagacgc
   149161 tcgtcgtggc aagagcccgc tgaaggcgcc tgatctcgac gcgcatctgg accctgagct
   149221 ttgcgtccag gttcgaaagc ggttcatcga agagaaaggc ggcgggttcc cggacaatcg
   149281 cccgccccat cgccacacgc tggcgctgac cgcctgaaag ctgccgcggc tttcgatcca
   149341 ggaaaggttc tatttccagg gacttcgccg ccttggctat ccgacgctcg atctcgtcct
   149401 tcggcgtgtt gcggttcttc aggccatagc tgaggttctg gcggaccgtc atgtgcggat
   149461 agagcgcgta gttctgaaag accatcgcaa tgtctcgctc ggaaggctcg agcccgttga
   149521 cgacgcggtc gccgatggag acctcgccgg aggtgatgct ttcgagcccg gcgatcatcc
   149581 tcagcagcgt cgacttcccg cagccggaag gcccgacgag cacgatgaac tcgccatcgg
   149641 caatcgcaag cgaaacgccg cggatcgcgg cgatgtcgcc ctgataggtc ttgtggacat
   149701 ccgtaagatt gatcgttgcc attacttctc cgtttcgacc agacccttga cgaaccagcg
   149761 ctgcatcagg acgaccacgg cgaccggcgg gataatcgcg aggatcgccg tcaccatgac
   149821 gtagttccac ggggtcgacg catcggtgaa atcgaccatc ttcctgaggc cgatgatgat
   149881 cgtgttcata cgactgtcgt tcgtcaccag cagcggccag agatactgcg tccagccgta
   149941 gatgaagagg attacgaaaa gcgccgcgat attggtcttg gaaagcggca gcaggatatc
   150001 ccgcatgaat cggaacggac ccgcattgtc gatccgcgcc gcttccacga gctcgcccgg
   150061 gatcgtcaga aagaactgcc tgaacaggaa ggtcgccgtt gccgatgcca tcaagggcaa
   150121 cgttagtccg gcataggtat cgatcagtcc gagatcgacg atcaccttgt aggtcggcag
   150181 aatccgcacc tcgaccggga gcatcagggt gatgaagatc atccagaaaa acaccatccg
   150241 cagcgggaag cgaaagaaca cgatggcgaa ggccgagaga aaggaaatga cgatcttgcc
   150301 ggcagcgatc gcaaccgcca ccacgaacgt attgaacagc aaccgttcga ggctgacgcc
   150361 gacgactcgc tcgacgccgc cggagagcgc ttcgctataa ttctcgataa gccgcgagcc
   150421 gggaacgagc ggcatcggcg ggcggatgat ctcgaccgag ctcatgctcg atgcgacgaa
   150481 ggtgtagtag atcggaaaga ccacgatgat gacgccaatg atcagcatca ggtgcccgat
   150541 caggctggag atagggcgct tctcaatcat tggcgatctc aaccatagtg gacgcgcttt
   150601 tcgacgaacc ggaactgaaa ggcggtcagt ccgatgacga tcgccatgag gatcaccgac
   150661 tgagcggcgg atgagccgag gttcaaattg acgaagccgt cgttatagac cttgtaaacc
   150721 agcgtttccg tcgccctcgc cggcccgccg ccagtcaccg agtggatgat cccgaacgta
   150781 tcgaagaagg catagacggt gttgaccacc agcaggaaga aggtcgtcgg cgccagcagc
   150841 ggaaacacga tcgtccagaa ccgccgggtg ccgcgcgctc catcgatcgc ggccgcttcg
   150901 atgagcgact tgggtatggc ctggagcccg gccacaaaga agagaaaatt atagctgatc
   150961 tgtttccagg ccgccgcgac gacgatcagg atcatggcat gattgccgtt gagcaacggg
   151021 tcccaatgga aaccgctgcg tctgagcata taggcgaagg tgcccatcgc cgggttgaac
   151081 atgaagagcc agagcatgcc ggcgacggcc ggtgcgacgg catagggcca gatcagcagg
   151141 gtgcgataga aggcctgccc gcgcacgacg cggtcggcgg ccgtagccag aagcagggct
   151201 acggccattg caagcagcgc ggtcaacacg ctgaagatca ccgtgacctt cagagagttg
   151261 agatagttcg gctccgaaag cacggcactg aaattcgcaa atcctacgaa accgctcttt
   151321 aagccgaacg gatcttcccg gatcaccgat tggtagagcg cctggcttgc gggccagaaa
   151381 aagaagacga tcgtcaacgc gatctgcgga gcgacgagca aataggggag gattttgttc
   151441 ggaaagacga cacgctgcac gagcaatctc ctgggtcacg atggtctcgg gccggatcgg
   151501 cccgggatca cgtcagggtg gcatgaccgc agaatgccgc tcgccatcgc aagagggcgc
   151561 gcggcacctg cttcgatcaa ttgctgattg ctgctgcgat cgcggcgtcg ccccgctcga
   151621 ccgctttatc gagcgccgtc ttggcatcct gttgtcccga cagcatcgct tcgaactcct
   151681 cgttgaggat gtcccgaacc tgcggcaggt tgaccagccg gacacccttc gagttttcgg
   151741 tcggcgcctt ccccatcatc tgcaggagtg gcgtctcacg cccggggttc ttctcgtaga
   151801 agccggactt cttggtttcc tcgtaggcag ccatcgtgac cggcatataa cccgagacct
   151861 gatgcagctt ggcttggatt tctgtctgtg aaaggaagtt gaagaactcg gcaatgccct
   151921 tgtattcctc gtcggacttg ccggcgaaca cccagaggct cgctccaccg gggatcgtgt
   151981 tctgcggacc gtgaccctcg taatagggca gttgaccgat cccgtagttg acgccgctct
   152041 tggcgatgtc gccgagaccg cccgaggatt cggtcaggat ggcacattcg cctgatgtaa
   152101 agagctgctt tgcctcggag gtgcgccccc cataacgaaa ggcgccgtcc ttggcgaggt
   152161 tcgctatggc ctggaaatgc tccacgtaaa ggggcgcgtt gatcttcagc tgcacatcgg
   152221 tgccgccgag cccgttttca ttggttccgt agggcatatt gttccaggcg gcgaagttct
   152281 ccgtctggat ccaggtcaac caggtcgacg tcatcccgca aggtgccgca ccgctcgtct
   152341 tgatcttctt cgcggcttcg aagacttccg gccatgtctt cggcggattg tctacgttca
   152401 agcctgcttt ctgaaaagcg tccttattgt agtaaagaat cggcgaggaa gagttatacg
   152461 gaaaggacag catcgttcca tccggcttcg aataataggc aacgatcccg ggaagatact
   152521 gcgatttatc gaaggtgaag ccgcccttct ggaggatctc ggcggccggc acgatcgcgc
   152581 cctcggccgc catcatcgtg ccgctgccgg catcgaatac ctgaatgatc gccggcggct
   152641 gcttcgagcg gaaggccgca atccccgcat tcagagtttc gggataggtg cccttgaaga
   152701 caggcaccac tttgtaggtg ctctggctcg cgttgaactc cttggtgagc tcctcgatca
   152761 tttcgttgtt ggcgcccgtc attgcatgcc accactgcag ttcggtggcg gcctgcgcct
   152821 gaacagcgaa gccgacgacg gccattgtcg tggaaatgga aatcactcgc atggcattct
   152881 cctcccttgt acgcgtccac acccgcgccg ctcacagata ctcccaatat caagcgagcg
   152941 acccggcatt cttctccacc gcacatttcc ttgaccagcc ggtccaggac gaaaaaacat
   153001 gcagccaaat caaagtgctt atcagccatc tctatgcatc cggcaccccg ccgaaccaaa
   153061 tagggtaagg ctgccgattg tcgagagccc ttccccaaat ggtcttaaga ctcaccgatg
   153121 gagagtgccg catagaaatc gaaggctcaa gtgaaaagga acatcttcct tgccgccgtt
   153181 gttttgggca tgggcggcga atgccggtaa cggctccgcc ggtgatcgtg aggacgaatg
   153241 atgagagtgc ttgtagtggg cgcctccggc ctgatcggct cggcggtttg cgcggggctc
   153301 catgaacgcg ggatggaggt cgtccgcgtg gtccggcccg gatcggcacc gagctccgcc
   153361 actgctggcc agaccctcga agtcgacctt cgaaacgccg gcccggaagc ctggcgaccg
   153421 catctccctg acatcgacgc cgtggtcaat tgcgcgggaa cgctccagga cggaccgggt
   153481 gaggacacgg aagcggtcca cgcgcgaggt cctgcctcgc ttttcagggc atgcgagcag
   153541 gccggcgtgc gccgcgtggt ccatttttcg gcaatgggag tagacaaggc gcagccttca
   153601 ccgttctcgc gcaccaagct cgagggcgat gaagcgttga tggcatgtga tctcgactgg
   153661 gtcatcctgc gcccctccgt cgtgctcggc cccggcgcct acggcgccag cgcgcttttc
   153721 cggggtctcg ccgcgctgcc gtggctcccc ttaatgccga ataccggatt gcttcaggtc
   153781 gtgcgccttg aagacgtggt gcgcacagtg gcgctattcg tcggcccgga tgctcccgcg
   153841 cgcctcgcgc tcgaggtcgc gggcccggag gctctcacgt tcaaggacgt cgtgagcacg
   153901 tacaggcgct ggttcggctg gcccgctgcg cctgtcgtga acgtacctac ccccttagcg
   153961 ggtctcacct acagcctgag tgatctcgcc ggggccctgg gctggcgacc gccgacccgc
   154021 agtaccgcgc agaaagagat cgtgcgcggc gccgtcggcg acgcccgggc atggatcgaa
   154081 aagaccggaa tagaaccgct ggcgctctca gacgcgctga cgagaacgcc ggtctccgtc
   154141 caggaacgct ggttcgccaa gctctatctg ctcaagcccg tcatcttcat cgtcctctcc
   154201 ctgttctgga tcatgacggg cgtcatctcg ctcacatcag gatatgaaat cggcgttgat
   154261 ctgatggaac ggggaggcgc cggcgttctc gccggaccca gcgtgatcgc cggggcgctc
   154321 gcggatatcc tcatcggcac ggcgatcgcg cttcgccgca ccagccggat cggcctctat
   154381 ggcgccgtcg ccctttctct gttctacgcg gtcgccggga cggtcctgct cccggaactt
   154441 tggaacgagc cgcttggacc gctcctgaag atctggccta tccttgtcct ccatctcgct
   154501 gccctggcta tcctggagga gcgttgatgc tttacttcgt tctcaagttt ttgcacatca
   154561 tcggcgcctc cgtgctcctc ggtacgggcg ccgggattgc attcttcatg cttctggcgc
   154621 atcggaccgg ccgtacggaa acggtcgcgg ccgttgcacg catcgtcgtt atcgccgact
   154681 ttcttttcac cgcaaccgcc gtcgtcctgc agccggtcac agggatcgcg cttgcctgga
   154741 acgtaggcta ctccctggcc gaaggctgga tcgtgctctc gattttccta tacctgatca
   154801 ccggtgcatt ctggctgccc gtcgtgtgga tgcagatgga gatgcgacgg ctcgccgaag
   154861 ccgcaagcaa agccgggaac cccttaccta agcgttacca ccagctcttc cgcctctggt
   154921 tcgccttcgg ttttccggct ttcggcgccg tcgtcgcgat cttctggctc atgatcacaa
   154981 ggccggcgct cgcatggtga gctcactgcc gcgcggctgc gggatgcggg cggaaaaccg
   155041 cgcagacttt tcctcctccc gccctagctt ttcagcgcca tctcgaccgc gcccgctgcc
   155101 ggcccgccat cgtatgtcgt cacaccttca agccacggag cgactgcatc cggatgagcc
   155161 ttcaaccaat cggctgcggc ttccttcggg tcctttccgt cgttcaatat cccgttcatg
   155221 atctcgtttt ccatgtccag ggtgaagcga agattcgtca caaatctcgc gacattcgga
   155281 cattcctgcg catagccggc ccgaatgttg gtatagatat cggcgccccc gtaattcggg
   155341 ccgaaatagg cgtccgcgcc cgagagataa tcgatccggt agcgcgtatt catcggatgc
   155401 ggagcccatc cgagaaagac gatccactgc tcgtcctttg ttgctctttc gacctcggca
   155461 agcatgccct gctcggatga ctcgacgagc tcccagccgg tcagcccgaa gtcaccctta
   155521 ttgatcatgt cgaggatcat gcggttgccg ttgttgccgg gttcgatccc gtagatcttc
   155581 cggccgaact tgtcggcgaa cttctggaga tcggaaatgt ccttgacgcc tgcgtccgcg
   155641 acgtatttcg gcacggcgaa tgtatatttg gcgccggtga ggttcgggcc gatcacttcg
   155701 atcgacttgt cctctaggaa agacttgcgg tcggcttcca tgctcggctg ccaatcgccg
   155761 agatagacgt cgatgtcctt gttcttcatg ctcgcatagg tgacggggat cgatagcagc
   155821 ttgctttccg gcgcatagcc gagcgcttcg agaatggtcg aggcgacagc cgtcgtagac
   155881 gtgatgtcgg tccagccgac atcggagaag cggacggtct tgcagctctc cggctcagcg
   155941 gcattggcga cgccgatcgt catgagcagt ccggtggtca ttgcagtgat ctgtttcagc
   156001 attgtcatgt tccctcttct taggttctgt atgcactgcg aaacacacgt caaaagacca
   156061 gaaaggcggc tcaccaaagt gcgccgcccg tgatctgtat gttctccatg gtgatacccc
   156121 ttgccccctc gccgcagagg aaggcggcaa gggctgctat ctcgtcgggc tggatgatcc
   156181 ggttctgcgg gttctgggcg gcgatatcgg ccatcgcctc ctccgtagtc cggccgctgc
   156241 cctcccgttc gacgacctgc ctgacgttgc ggcgcatcag ttccgtttcc acccaggtcg
   156301 ggctgatcat cacgcaggtg acaccatgcg gcgccccttc gagcgccacg cagcgggtga
   156361 gcccgagcaa tcccgacttc gaggcgcaat aggccggatt gtccttccag ccgacagtgg
   156421 cagccgtcga gcctatattg atgatccgac cccatttgcg cccgatcatt ccgggcagca
   156481 gtctccgggt catacggaat gcgccgttca gattggtatc tatgatcttc agccataatt
   156541 cgtcggaatg gcccgacacc ggctgctctg cagtcgtacc ggcggcattg acgagaatgt
   156601 cggtggggcc gcatgcggcc tccgccgccg cgacgaattg ctcgatcgcc tcgctgtcac
   156661 gaacgtccag gtggccggcg tgaaccgccg tgccggcagc ggcgagccgc acccggatct
   156721 cggcgatctc ccgcggatcg ggataggcag cggcatcgcc ctgacggccg gacgcttcgc
   156781 ggacgaagga gccgacggcg acattggcgc cgtcggcagc aaacgcctcc gcgatcgcca
   156841 gcccctgccc cgtcaagccg cctgtgatga ccgcgctgcg gcccttgagc ctgcctgtca
   156901 tgactgatcc ttcaatggct tgccgagcca gtcgcgatag aacccttcga ggtccggctc
   156961 gaaatcatgg acgatcgggt agccgggggc tgccgcttcg acttcgtgca gatgcgcgca
   157021 ttcggggcag aagaactctc ggatctccat ccactgagaa tccgggatat cgctgttggg
   157081 gtagatttcc cgcaagctct cctcggtgtc gcgaacgttg atcgccgctt tcagtttcca
   157141 gtttttgcga tagtcgccga aggaatagcc gcactcgcag cgggtgatcc gaccctcggc
   157201 gctgtcgcag atgaagaggc gatcgccgac cggcagcagg acggcctcgg cccaggccac
   157261 gcggtcctgc agcactgcca gatacttgaa gaatcggtcg tcgtccttgt aggcgctcat
   157321 gatccgccgc gtctgcggcc aggggagcgt tccgttgacg aggtcgttga tgatttcctt
   157381 cgaatatgtg gtcatggctc aattctcccc agcgatggtg aaatcggagg caagccccca
   157441 gaattccctg aagtccttgg agaagcgcgg cgagagcttc atcgcgctac gatacatctt
   157501 ggcgacctcg ggagcgaaat ccgaagcctt cacgcgcagt tgctccctga ccatccactc
   157561 ggacacggga atggccttcc tcatccgttc cctgcggatt tcggcacggc gggcgacggt
   157621 ggcatcgatg tcggcctgcg gataaccctc ggcatcctcc ttcaggatga tgccgaacac
   157681 cttctcggcg gcttcgcgcg tcaggaagcc gttttccacg tcccacgccg tcttgatcgg
   157741 gtcgcgctcc agcacgtcgc cgaagccacc gccgccatta taggcatggc tgaaaatgtc
   157801 gcctgccttg tgcggccggg tgatataggg accctcctcc cagacctgtt ctcccttata
   157861 gatgcgctcg aaatccgaga ccagcggatc ggtgcccggc gtatgtgcca gcggctcccg
   157921 gcgttcggcg cgttcgtgaa tatcggaatt cctgaccgcg tgatgttttt cgcaggtggg
   157981 cgccggatag ccgccgcaca atccgccatt gtcgaacacg cgcgaggaat gctccgatgt
   158041 tacgaggcga aggtgatcgg tcttgttgat gagccaggtc gagatgaagg cgcagccgcc
   158101 ccggtacttc ccggcgccgc cggagttcgg cacgatcgag cgcccgatat agaccatcgg
   158161 catgttctgt tcccagatct cgatattgcc catgtccgat tccggattcc agccgacata
   158221 ggcagtatcg agtccgtcct tgatcgccag cgctccggag ccggcggcag cacattcgaa
   158281 atgcgccatg ccgaaaccgg tgccgtactg gctggtgccc cccatctcga tcatcggtga
   158341 attcacctga ccgacaaagg cttcctcgac gaatccccgc gcgatgaaac cgcgcgagag
   158401 cagccgctgg aagactccgt aagcaggaag cagcaatgcc caggaggttg ctgtcgccgc
   158461 catctcgttg tcggggttcg tccaggtgcc gtggggaatg ttgatctcag tcgccaacca
   158521 ggcgccgtca ttgaccagcc cctcgaagtt catgtgctgg gtcagcgtca cgaacatacc
   158581 gccgtccatg ccggccgggg tgcagttcat cgaatgatag ccccagggct gcgtgccgtc
   158641 gaagtcgagc ctgatcttgc cttcgctggt gatctccatc tcgatcggaa tattgtagag
   158701 ccagttcgga tcggcgagtg gctgaaagcc gggcttaccc tcggtcacat gaccataaaa
   158761 ggtgtggccg cgataaattc cgggcaccgt gagctggcgc gtccgggcaa gctgcgctct
   158821 cctgccttcc tcgatgaatt ccttggaaag ccgctgccaa tattccaggc cgatctcttc
   158881 gatgagctgc ttgacgttct cgcgcatgtc gatgcaggcg gcgaccttgg ccttctcatc
   158941 cagcacccag taaatcggca tgcgcagatt gcgctcgcag cggatcacgt agtcgcggcg
   159001 aatctcgtcg ttttcgccga ttttctcggc acaaacgaac aggccctcgg tgaagcgttc
   159061 ctgagcaagg cagacatcgc cgccgggcgt gatgcccccc gcttcgagtt cgtggcagac
   159121 ggcaccggcc cagccgacca gcgtgccctc gtgaaatatc ggcaccacat ccatgacgtc
   159181 ggggacctgg accgtaccga tgaaggcatc gttgttggcg aagatgtctc cgtcgcggat
   159241 gcaaggattc tgctcgtatc cgtttctgat catccatttg atgaaccggc tcatcgtgtg
   159301 cacatgcacc atgatgccgt tcgaaagtgc gattgcatcg ccttccggcg tgtagatcgc
   159361 caccaccatt tcgccgactt cccgcacgcc cggggaggca gagatgcggc gcgccatttc
   159421 gcgcgccgag acgcaatagg cacgcagttt cgtatgcagc gtctcgaatt tcagcgggtc
   159481 ctgcccgcgc aggcgaagtt cggtgatgcc gtcatagcag ccggtctcct ccatcaggcg
   159541 ttcggattcg agcagccgcc gctgcagggg atttgccgtt ttgtccagca tgtttgtcat
   159601 ccttcagctc aggcgtggtt gtagtgaagc agcgtccatt catcgatgaa gacgcggtcg
   159661 ttcggatgca ccaccagcgt cgtcgccgga tgttcgatga tcgcgggacc gatcacttcg
   159721 tgtccgggct cgagcagatc catctcgtaa agatcggcct tgtgccagcg gccaccgata
   159781 taggcttcgc gcatgccctt gtgggcggat cgcggatcgg cggtcccgag aggccgcctg
   159841 acgagcaccg gcttgatctt ttcggcggtg gcgatcacgc cgagctccat cagcgagaag
   159901 cccgcctcgc cgtatttcga gacgcggtga ttggccttgg cgtagacgtc ttcgaattgc
   159961 gccaggaccg cgcgcatgtc gcccgcagtg tcgatcgaag gcagcggcgc cagcacctcg
   160021 acgtcctcca gctggccggt gtaacgggcc atgaagaagg gaacggcctt gatcttctcc
   160081 cgcgcatggc cgtcgatcag catctcgtcg acagcggctt tttcgaggtc cttccacacc
   160141 tgggtgacct gcgcgccggc tgcagcaagc ctgtcgtcgg aggcatgggc gccgatatcg
   160201 atctgggtcg agaccgaatg ccggcgcata tagtcggcag tggtgcagcc gaaggcggag
   160261 aaggcggcag cgaactgaaa cgtgatgata tccttgaagc cgatgcctct cgagcagccg
   160321 gcaagatgca gcggacccga accgccatag gagagaagcg tgaactcgga cgggtgaatg
   160381 ccctgacccg aaatgacgcg ccgcaacgca ttgttggcat cctgctcgag catctcgatc
   160441 atgccctccg ctgcttcttc caaaccgaca ccgagcacat ccgcacattt ttccttgaag
   160501 gccgcacggg ctttttcgac ctcgagcacc accttgcccc caagaaagta atgcgggttc
   160561 aaccggccga ggatcgcatc gcagtcggcg attgtcgggt cggtgccgcc tttggcaaaa
   160621 cagatcgggc ccggatcggc gccggcgctt tccggcccga gcgagacctt cctcgtcagg
   160681 ggatcgacct tgagaatcat gccggcgccg gcaccgatcg tatcgagatg aagcgtcggc
   160741 acattgagct tgaagcgatc catcagcggt tcgttttcaa tgcgggtctg accgcgcgag
   160801 atgacgccca tgtcgaagga ggttccgccc atatccgaac agatcagcga gtcatttccg
   160861 atcagcttgc cgatataggc cgcgccgaga attccgccga tcgggcccga gatcatcgtc
   160921 tcatgcagac gcggatggtt gatcgacgtc aggcctccga acgagagcaa tgtctgtacg
   160981 ccgtacttga atccgtattt ctgcgacgcc tcctgaatac ccctgagctg cttgcgcccg
   161041 cgcgatgtcg cataagcttc gatcagcacc gagttcagcc gcgattgttc gcggatgacc
   161101 gggcgaacct catggctggt atagatgttg atctcggcac cggcggcggc aacctcctcc
   161161 cggcatatct cggcgatgcg cttctcatgg acgggattga cgtggctgaa gatcgtcatg
   161221 atgcagatgg catcgacctt gtcgcggatc agagcacggg ctgcggccgt cacctcatgc
   161281 tcgtagaggg gcaggacgat atctccgaaa tgatcgacgc gctctgtgac gccatgggtg
   161341 cggcggcgcg gcaccagcgg atcggggtgg gcgtgagtga cggcgtggag ccggtcggca
   161401 taggaatagt cggcccaggc ctgcagtccg cggcccatca gcaccatgtc ctccaagccc
   161461 ttggtggtga tcagccccag cttgcggccg gtgcgcgaga gcagcgtgtt gagcatgccg
   161521 gtgccggaat aaagcaccac gtcgagtccg gagaaaagac tatcgaggga gataccccag
   161581 gcgtccgcgg catcggcggc ggaggaaatg aagccctccg cctcgttttt cggtgtggtg
   161641 gcggccttgc cgatcttgaa gtgcccgttt tgatcgacaa ggatggtgtc ggtcatcgta
   161701 ccgcccgcgt cgatgccgat cacgattggg ttttccaagg tcctgccctc catggctttg
   161761 ctgatggggg gagcgtagat gcgaatttac agctgcgaaa tgtgccaaaa ggcacaatga
   161821 ccggcagggg gaacagtggt agacgaacat atgagcggcg atgtgttctg gaatatcctg
   161881 gcgcaagcga tcagcgccac cggcaccgat aggcatgtcg accggctgat cgacatggtc
   161941 ggcgctgtgg tgccgcagaa cctcatcacg gtcacgcgct attccgccac ccgcaggccg
   162001 gaattcatta agcaccgcgg ttactccgac gagatggtgg cgcgttacct cgatacctat
   162061 tatgtgttcg atcccttcta tgcctattgg cgcctgacca ggcgcgcagg gatcgtgccc
   162121 ctcaagagcc tggcggacgg cgctcccaaa cgcggccgct acatagcgga gttcctggcg
   162181 caatccgaaa tctgcgacga ggtcggcata ttgctggaag acggcgacga ctggtgcctc
   162241 ggcatatttc tcgaccgctc cacatcgatg ttcagcgatg gcgaggtcgc ggcgctgtcc
   162301 ggccgctttc cggttttcga agcacttcat gcaaccgata cccgcacgcg cgaccccaat
   162361 ctcaggcgga ccagcatgcc cgaagccatg ggagaagcgc cggtgaacgc cgtccaggct
   162421 tccctcatcc tgtggccggg cctgacggca cgggagcggg aactcgtcga tctcattctg
   162481 caagggcatc cgaacgccac gatcgcgtcc aggctcggga tcgcaccggg cacggtcaag
   162541 aaccaccggg cgcgcatcta tgaaaagctg gacatcacaa ccgagcgcga actcttcctg
   162601 caggtcttcc agcaataccg gctttcttaa ggagctgccg aaccggcgat caagccgcgc
   162661 ggcggcggtg ccggaacaga tgcgctcgcc tgtggttaca cagccagccg aaatcacagg
   162721 aggttgtcga aatgagcaaa accgatgtcg aacaggccca gaaggacgcg cgaaaacagg
   162781 ccgagaacac gagcggcggc ggtcatctgg gcggcactta ttacggacag gaaccggatg
   162841 ccaaaacagc gacgacggta aagaagaagg gggacaaggc aaggccgaac gatggcagaa
   162901 actagccagg cgaggtctct cctcttcgct catctctgtg cacattgtcg gcagcgatgg
   162961 gtctgcgagt gggaagggtc ttttcagccc aatgacttgg tctggctggc aactgtgttt
   163021 gtcaggtggt tcgtcggaag gttgttttgt ccctgatgat ggcgtttgcg atggcgagca
   163081 atttgcgggc aagcgcaatg atgacgacct tgaagggctt gcctgcctcc ttcatttggt
   163141 cagcatggga cttaaaagca cggggcatac ggctggctgt gagcgccgcc atgtagagcg
   163201 cgtcacgtat ccgcttgcga ccgccgcgta tatgccgctt tccccgtgac gtgccgctgt
   163261 cgacattgaa gggcgcaaga ccggcaaggg ctgcaatcgc cttggccgaa cgattgccga
   163321 gttctggcat atgcgcgatc agggtcaatg cggccacggg gccgatgccg ggaatggaac
   163381 gcagccttgc ctcttgttct tgcaaggtct tctcggcctt cagaacatca cggcatgcca
   163441 tttcgatgcg cgcaacctcc gcgtcgagcc aagccatatg gctttcagca ctgtcacgct
   163501 cgatcccctc ggtctcatga aggcgtgtcc gctcttgctg gcgcatggcc acgagctggt
   163561 cacgccgcgt gtgaaggcgg gcgagcacgt ggcgggcggg atcgtcagcc tgagttgaga
   163621 gtggcaggct ttgacccatc cgggcaagca gacgtgcatc gatcgcatcc gtcttggcaa
   163681 gaaggccgat cgccttggca aagtcgcggg cgcgggcagg attgacgcgg gaatagggca
   163741 actcccgggt ctccagggct atgcgcaact gccgatcgta acgcccggtc gcctcaaaga
   163801 cgatatgaac gcctctgcca tcaaggccgt cgagccacgc ggaaattgcg gccggagtgt
   163861 tgtcgatacg gaaatggcgc tcaaggccgc tgtcgaaaaa atctagatgc gcttttgcaa
   163921 tatcgcatcc gatgacatca ggatgtatca tgggactgcc ttatcctgtg atgcgaggtc
   163981 cgctgtgacg gcctccgtca actgttcagg ttagggattc gaagcgggcg gaggaccaga
   164041 gccagcacac ggtctttaaa gaccaggatt ccgacggcct tccgcccgca cccatataag
   164101 cacagtttcg acacacagga ttcctgtgca caggattgaa ggcgttcgga ctgcgggaat
   164161 ttgaaatgtc atcccgacgc gtcgcgtttt tcaaggaggt cccatgcccg actatcagcg
   164221 gctcccggta agaccagtgc caggggcgat ggtcgtcaaa ctctatcgct ccggcgacgc
   164281 agtccggggc tatgtgcgaa aggtcagcga tccctccgag gatgacgtca tcttcccggg
   164341 agaggagatg gagccggatt ccgccttccg cctggcagca agccataggg aaggatcgct
   164401 gccaatctat gtagagcttg tcgaggacgt ccaatgggac ccgtcctggg gaacattgga
   164461 cggttgaaat ccacggagta cccgcggttc aacccgtcgt tccggcatgc agctcgcgga
   164521 acgtgaccga atagcgcagg ccgtccagcg gcggaatgga atgctcccac tcggaccgcg
   164581 cggcaccgga gaggagatat gcggagccgg gctccagagc gaccgatgcc cgctcccatt
   164641 tgccggcgcg ccttcggcga agcctgaagg tgcagggagc gaggagcgaa acaccgacga
   164701 ccctgccgaa caccgccttg tccctgtgcc acccgatcgg tgctcctacg tcgtattcgg
   164761 taatcagagc ctgctcgagt ttctccgccg gcagcccggc gaaatcggcc gccaattgcc
   164821 gtagcggcaa aagaaaagag ggaatgtcgt cgatcttgcg gaccgattcg gtatcgaagt
   164881 cgtacttcca gccaaacgag accacccgtc gcttaccctc gtagccgtga aagtcgaaag
   164941 gcctgaagga aagtcctggc aataccccca ggagcgcttc ctgaagcttc tgcggaacga
   165001 cctccgcttg gtaacgaaag ccttccagca ttgtgggggt gtacccgaaa agatcttcct
   165061 gcatcaaaat acctcacagc ggacgcacgc ccgaggcgcc ctcgtcggag aacgtcgtat
   165121 aaacaaaaaa ggggctcgca cgttcccgtg ccagtgcaat cctcggcttc aacgcgaggc
   165181 ttgcgggaga atctcagcca ggcagaccgg ccgcaggttt cgggcgtcca cgcccacatc
   165241 gaactgacgc gggaccggct tcaatctgcc atgggagtgc ccgtgcaggt tgaccgacct
   165301 cttgcccatc tggttccagg tccggaatgg atagtggcag aggacgagca gccggccatc
   165361 gaccgtcagc tccgcataat gctggacgct gtgccagccg ctcgctgcgg tcgtatcgat
   165421 cggatcgttg ttgccgatga tcagatgttt gcggccgttc agccgtgaca gcatatcctg
   165481 tgcaagaccg gctctctttg ctgcgaagtc gccgaggtgc cagacctcat cctgcggaga
   165541 tacggtttcg ttccaattga cggtgagggc agcatcatgc tcggccatgc tggaaaatgg
   165601 gcggcggtcg atgcgaagta cgcgcgggtc gccgaaatgg gtatcacccg tgaaataaat
   165661 catctcgccg gccgcaaacg aataatcgaa gacgccgcgg aacattcatc caattgccga
   165721 gacttggcaa ccccgctgcc cgatctctgt cgaaccggac aatgcggcgg cggacgtcaa
   165781 gcgccctttc cgtcggcgaa tttctcgatc gattgcgcca gttcggggtg ctccttagca
   165841 taatccgaga gcggtatccc ggcgactgcc gcctcccatg cctgacgcac ggctcgcacg
   165901 ccggcaccgg ctccgcccgg gtggcttacg actccgccac cgcagagata gagcagatcg
   165961 gtcgtacgtc cggtgcgtac aaaggtctcg ggcgcctgtc ctccccattg gccggagcac
   166021 acgaccggca gcgggcaatc ctccctggaa aacagcggcg tgcttaccgc cttgaaggac
   166081 ttcacgaaac tgtcgtccgg ctcccagtat ttgacgcgga tgccgttgat ctggaactga
   166141 tccactccga ggaggcgcca gaactgctgc cacaccgaaa actccatccc caggccgcca
   166201 tggcgcgtga gaatgtccca gccgttacgg tgggcgtgga gcacgaggtt cgagcgcttg
   166261 cgcaggaagg cgacaccgcc catgccgatc gaattgatat tgacgaccgc cgcattgcca
   166321 ccagcggcga ccacgagatc gtggttccgc atcatctcat cgggatcggt atgggatatg
   166381 ccgaaggcat acatgacttt cttgccggtc ttctgctcat ggtcgcgtat cttcggcatg
   166441 atggcggcga tgcgcgcact cagcggcgaa taggccgggc tcatcagctt ctcgtcgtcc
   166501 ttgatgaagt cgacgccgga agaaagcagg tcgcctacga gcgctgccgt ttcgtccggc
   166561 agcaggccga gcgccggctt gacgatcgtg ccgataatgg ggcggccttc gacaccggtc
   166621 aggcggcgac tgccggcgac cccgaattgc ggacccggat gcgccgccgc gaactccggc
   166681 gggagtttca tgtcgacaac acggattccg gtcatgcctt tgatggcata gacgccgccg
   166741 attgcaatgg tcatcagggc ggacaggtcc gttcccaccg cttcaagagg atatgcgatc
   166801 tccgcatcgg cccggttgaa acgcgttgcg tctccagcct cgtccggcaa cgacgcccgg
   166861 tcggccggtg ggaggtggcg aatggccacg acgcgtgcag ctgcccgccg cttcagctcc
   166921 tccgtttccc ccggcacagc aacgaacgtc cccgttgatt ggtcgcttgc gatttttctc
   166981 gccagcgcct cgacgtctcc tggtgtctct atccggtagg ttatgtggat cactgccgac
   167041 gctcttccta ttgatcaggt agcttcttcg ccttaactgg tataatgagt acctaagttg
   167101 aagcaagaga aatctcgcct gccgtaaaaa acctgcctat agagaatgag ccgcaatccg
   167161 ggagttcaca tggctatcca atccgaccct attgtccgca ggaaactgtc cgacgaggtt
   167221 tttgcgcgcc tgaagggatc gatcgagagc ggcgaactgc aacccggaga cgaaatgcct
   167281 tccgagcgca tgctgatgga gcgcttccag gtcggtcggc cggccattcg cgaggcgatg
   167341 caggcacttg ccaatatggg tctgatcgag atttcacatg gcgagagggc aaaggtgctg
   167401 cagccgacgg cgcggtctct cctccggcag gtggatgccg ccgcaaagat catgcttgcg
   167461 gcctcctcgg attcgctcga acatctgaag agtgcgcgca tctttttcga gcgcggcatg
   167521 gcgagggagg cagcaagccg ggccgacgcc caggacatcg cggcacttga ggagaccttg
   167581 aagcgccagc ggtcggcact cgaagattcc gatgccttca tcgcggccga catggcgttt
   167641 cacacccgca ttgcccagat ttccggcaat ccgatataca ccgccgtcag cgaggcgatg
   167701 ctcggctggc tcaaggagta tcatacggag atgctgatct ggaccggacg agagaacgtc
   167761 acgctcggcg aacatgagga gattatcgac tgtatccggc gcggtgatcc agacgaggcc
   167821 gaacaggcga tgatacgaca cctggagcgc tcccgcacac tctatgcccg gaagggccgc
   167881 tagatcgaaa tggttcagag cggaaaaagt gcggtccgtc ttccgcatcc gcgcctcaac
   167941 tctttgcagt cgatcaagcg gttcgcgtcc gaccgaatgc gcgcagcagc aagttcacgg
   168001 agacggcgat cttgtcgata tcgggaacat cgcgggaata gcggccggtg tagagcttta
   168061 cgatcatctt gtcgcgctca gctccacgca ggtcgtagtg aagatgaagg tagtagcgct
   168121 gtttgtcacc ggtgcgcgtg atatctccgc gccgctgggt aacctgcttc agatccgcct
   168181 caagaggcgc gaagccttct atattcaggc cgaccttggt cgatttgaac cgcgtttccg
   168241 tcgaaacggc cacaactgcc ttgtccaggg aaagactgac gagacgccct tcgacaccgt
   168301 ccactttcac cgcttcgtcg agcttgaacg cctggagcag gcgccgcggt ttctcgaagc
   168361 agatgaggga cgcgatgatc agcaccacga tgttgatgcc ggaccaaagc gccgcgatcg
   168421 ccgagaatga accctctatc cgcgccgtct ccggaacgat gttgatcaga aggccaagcg
   168481 cggtgaccac gatgaagcca gcgatccagg tgaaagtata ggcgtcgaag ctattttcct
   168541 cgttgctgct gcccttgggt gtcactttga agggtttgcc gaaaggcctg accaagctcg
   168601 aaaggacggt cggcagcatg cgaaaggtcg agaaagtgcc gaccgcggtg gagaccagcg
   168661 gaaggtagcg cgtcggcgtg agccagaaca tcaggaggaa ataggccgca agcaggggca
   168721 cctggttcga gacgtagtcg gcgacatcgg tgaaatagag cggcagagcg ccgaaccaaa
   168781 gatagactat cggaataagg aggacgatga agcgaacgag atactgcaca agccacgaca
   168841 tgggcaggaa catgacgcgc tgaaacagcg agagcccagg cccgcgcagg gggccgttat
   168901 ggaggtaaag cgtctggatg ccaccctgac accagcgctc gcgctgcacg aagtagccgg
   168961 tgaggttctc ggccgccaag cccattgaaa gccgctcgtt gagatagcga gtcttgaaac
   169021 ccctgttcag catcgacagc gtcgtcagca gatcttcggt gatcgactcg gttggaaacc
   169081 cgccaatggc gtcgaccgct ttgcgccggg cgatcgaaca ggagccgcag cagaagctga
   169141 cgtcccagcc gtcgcggctc ggcgcgattt cgtcgaagaa caggcgctgc tcgtcaggcc
   169201 acagattctc caaaccgaga ttggactgta tcggatcgac attgaagaag tgctgaggcg
   169261 tctgcacgat gccgatcgtc tcgtcgagga agaagggcaa agtccgtcgt aggaagctgc
   169321 gatagggaac gaagtcggca tcgaagacgg caatgaaatc gcctgaactg gcgcgtaaac
   169381 cgttgttcat gttgcccgct ttggcatgcg cgttgtcgct gcgcgtgacg tggatcgcgc
   169441 ctcgtccctc gcagaaggtc ttgagccagt cgcgccggcc gtcgtcgagc acataaacct
   169501 tgagcttgtc tttgggatga tcgagcgcaa gggctccgac gatcgtccgt tcgagaacgt
   169561 cgagcggttc gttataggtc ggtatgaaaa cgtcgaccgc aggaagttcc ctttcattcc
   169621 cggcgaagaa cttccgctct aggtcgtctg cctcggaact gcgatccaca tagcggctca
   169681 tcaggatgag gaagagcacc acctcggaaa aagcgaggaa ctccgcgatg aagacgaacc
   169741 atacccaata gaaattggcg ccatcggtcg gatagggcaa aacggtttcg gtaaagcgcc
   169801 agatgaggta acgcagcgca atggcagcca cgaaaacgca tgtcaccgca cgcgcccagc
   169861 ttttatggcg cgaccagttg aacgggccga gcagaaaaaa ggcaaggacg agcaatgtcg
   169921 gcgcaagcgc tagaagagat tgaaccacaa gctttgaatc cactgcgcca catgaaggct
   169981 gcgttttgag aaccgtacct gcgccgtccg accgacctgg cagaagttcg cgaaatcggc
   170041 gttgagtgcc gagggcgcga gggtgacgcg gatgcgcgca ttccgctcat ccgcctccgg
   170101 ctcgttggcc gccagagagt ctttctcgac gacggcggac gagcccttga ctgcctggac
   170161 ccggcccttg aagacatcgc cccgaccgaa gagccgaacc tcggcgtcgc ggccgggata
   170221 gatttcgtca tagtcgactt caggaacgag gatatccacg aacagatcgc ggcaatcgag
   170281 gatgcgcatc acttcgctgt tcagaacgac atttgagccg ctgaccacat ttctggtcca
   170341 cacgacaccg tccaggggtg acgggatcgt tgccgattcg agattgagga cccgcctttc
   170401 ctcctcggca atctgttggt ctgtctgttt tgcccgagtc tcgttctccg cgatccgcgt
   170461 attgagatcg tggatgcgga cgatgacctc gtcctggcgc tgccgggaat agggcacgtc
   170521 gttctggccg tcgccgacga tgaatatgcc ctttcgcacg gccgagaggc gttcctgcaa
   170581 caattcaacc gtcaggttgc tgatctcgag ctcgccgccc gcggccgcac cggcggcttc
   170641 cgctgattcc accatcttgc gggtaaaaat gcccttggac tcgaggtcct gccgccggtc
   170701 cagatcgacc cttgccacca cctcctgcgc gcgcgacacc tcgacccttt tctgcagaat
   170761 ctggagctca cgctccagac tggcgatggt cgcgttccgg aaaatgtcca gccgccccgc
   170821 aagatcgtcc cgcagccgta cgagttcgtc ccgctcccgc cgcaacgccg caacgcgctc
   170881 gagggcggtt cgatgatccg tgcgcagcga cgccagcacc gccctgttga cccgctcgtt
   170941 gctgattgtc gcgagcgttt caccctcttt caccggagtc ccgatccgag gcggcgcctt
   171001 gtcgatctca ccgtcgacgg gtgcgtttat gacggcaaaa cgggcgttca ccgtaccgtc
   171061 aaggctgctg tatccggtca atccgggcag caggacggcg attgcaagcg ccagcagcag
   171121 gatgccgacg gtaatacgtg tgagccgatg attgaggatc atgtccaatt actcactcag
   171181 gacggccgga tcggctgata cactgccatg gccatttgca agaggctgtc gccgggaccg
   171241 cgccccgctt cgtctctttt cgtcacgatt gaatggtatc tcgtagcgaa caaccctcaa
   171301 atctgcttgc tttgaccgtg aaccgcgtaa aacttcagcg agcgaaggga gaacccgctt
   171361 tactctaagg tttaaggata gcgcgttgac aatgttttgc gataggtcgt gaggctgcat
   171421 cctctccccc tcctgggagg agcgactccc gtcgtagaag aaagacgggg cgtctgagcc
   171481 gccccctttc ggtgattaac ggagatttcg atgggtcaag ccctacgcat cctgacgaac
   171541 gagcgccaaa ggctgctcgc agtccgctcg ctgaattccg ttgaaagcgc tccgacaccc
   171601 gaactcgcga ccctcgccga gcttgctaaa ggcgtattcg gcgtctccta cgccgccatc
   171661 aacatcatcg acgaggattg gcagaggatc gccggtcagg cgggcttgag gatcggcgaa
   171721 tgctcgcgcg agatgtccat atgcacgcgg gtcgtcttcg aagacgaatt gcttgttatt
   171781 cccgatctga cggaagacca ggacctgaga tcgaggccgt acgtcgtcgg aagcccgcat
   171841 ttccgcttct acgccggcgc gcccgtctat ctggacaacc tgcccgtcgg gagcttctgt
   171901 attctcgatg gccggcccgg aaatctctcc gacggacagg ccctgaacct gcgccgcttc
   171961 gctgaagtcg ccagcgctct gttgagcctc cagaaagcca atctggttat ggggcttgcc
   172021 cacaaccagc tacagaatgc ggcaatcacc gatccgctca cgggtctctt caatcgctcc
   172081 gccctgtcct cgatcgtcga tggggcactc gacaatgcga tgaccgcggg tcagactttc
   172141 ggggcccttt atctcgacat ggatggtttc aaggcgatca acgacaagct gggccatcag
   172201 gtcggcgacg cggttctgta cgaggccgcc aatcgaattc gctcggtcat cagagcgggc
   172261 gacattccgg ttcgcatggg cggcgacgaa ttcgccgttt ttgttccaaa tccgcccaat
   172321 gcaccggccc tggcagcggt ttcgcagcga ctggtctcgg tttttcgcga gcccgtagag
   172381 gtcgatggcg aggccatcca ggcgcgtatc agcatcggcg gcgccctcgc cccggataac
   172441 gggcgccggc gggcggatct gctgaacagc tgcgacaagg ctctctacgc ggcaaagcgg
   172501 ggcggtcgcg accggttcgt cgtcgtcggc gcctgatctc aatcttgaaa ggtcgtgaaa
   172561 tgagagctgc atggtatgag aagaatggcg ccgcccgcga ggttcttaag gtcggcagcc
   172621 ttcccgagcc tctccccggc cccggagagg tccgcgttcg catacatgcg tccggcgtta
   172681 atccgtccga tgtgaaagca cgggcgggaa ggccggtcat cgccccgcaa atgatcccgc
   172741 atagtgacgg cgcaggcatt atcgacgccg taggagccga ggtggcaggg gaacgcatcg
   172801 gcgaacgggt atggacgtgg aatgccgctt ggcgacgttc gaacggcacg gctgccgagt
   172861 atgtcgttct cccgcaggat caggcggtcc acctgcccga taacgtatct ttcgaggaag
   172921 gcgcctgcct cggcattcca gcgctgacgg cgctgcgcgc ggtgaccatg gacggatccg
   172981 tatttggaag aaccgttctg gtggccggag gcgcgggctc ggtcggcgct tacgccattc
   173041 agtttgccag gctctacggt gcggcgcgca tcgtcacgac cgtcagttcg gcgcaaaaag
   173101 ctgagatctg cttgaggctg ggagccgacg acacgatcaa ctacaaaacg gaagatgtcg
   173161 tcgaccggat aaaggacatc accaacgggc gcggcgtcga tcgagtcatc gaggtggacg
   173221 ccgccaccaa tgccaagatg ctgcctgaaa tcatcgcgca ggacgggctt ttggtgattt
   173281 acggctccag caagcctgat atctcattcg agttcttgcc gatgatactc gccggcatcg
   173341 ccgcgcggtt cttcatcgtg tatgagatgt cgccggaagt gcgtgccgag accgtcagcg
   173401 cgcttcattc tcagctcagg tccggacttc tgagacacca cattgccgag atctatgcgc
   173461 tggacgacat cgctgccgct catgaggcgg tcgaaagcgg caagacggtc ggcaatgtcg
   173521 tcgtttcact aagccccacc ccctcgtaga gcgttcccgt ttttctctga aacgcggaac
   173581 tgcggtagat ccggcgcccg gcagcccctt cggcagccag ggcatccggg ctcgtcctga
   173641 gcattgcggg cattgcgcgc cttggtgctt ctaaccgctg aaagcctctc ggtaaccccg
   173701 caatgaacgt gcgccggttc ggtgcgcggc aaatttcgac gtcgtcgcct agaacgaagt
   173761 tgacacgaaa cagatttttg tccaacatac atataccacg tcttctatga gaagacaaca
   173821 gttttcggaa cttctgtaat gtcggttcgc cctttatcct cggtgctcaa gaccctcgct
   173881 acgttcgagt gcatcggcgc tgcagcggag ccgttgcgac ttgccgatgt tgcgcgccag
   173941 ctcggcgaag cccggggcgc cgtccatcag cgtctcgtca cgctggtgga agccggctgg
   174001 atcgagcaga caaccgatgg ccgttatcgc ttgacgcttc gcatcgtcgg gcacgcggca
   174061 atggctctcg aacaatccaa ccttggcgcg cgcttcgccg gcgtcctgga agagatggtc
   174121 acccagagcg gtgagaccgc ctcgctcgcg attctcgacg gaaagtccgc cgtcatcgtt
   174181 cgccgggtgg agtcacgcgg catcctgcgc gcggaccttc ggataggaac gcagctccgt
   174241 cttgaccgca ctgccttcgg ccgggttctc gtgtcgtttg cgcgttcgga aatagtcgac
   174301 cgtctgaggg cggagggcgt cgaactgccg ggtgacgaga tcatcgccga agtgcgcaag
   174361 tgcggctacg ccatttccga ggtcgagggg ccgcgaaccg tatcggccgt tgccgccccg
   174421 attatcgatg cgcagggcga atgcatcggc gcactcgcgc tttccggccc gttcacaggt
   174481 ttcgatactg acaagtgcgc ccggatcgtc gtcgcagccg cggcggcaag cgccgcgcgc
   174541 ctgcgaggag agcaatgaaa tgagcgccct gacgaaaacg gtgcctgagt cggcggccca
   174601 ccgcatcgcg cggctgatgc gttcgccggc cgatatcatg aagcccgaaa ggctcgccgc
   174661 catccagccg tcccgcgtca gcgcctcgcg cgcactgatg agccgcgcgg tccggcagcg
   174721 ctggcagatc ctgtgcaagc ggttcgacat cgacgccaag ggcaacggcg tcgccgaata
   174781 ccgcatcgac atcggcggct ggcgcttcag ctttcccgtc tattcgttcg agccctcccc
   174841 gcacggccgt acgggccgca tcatcggtcg ggcctgggat atgatgggag ccttggtcga
   174901 aggcgatatg agcaggcggg atttcgaaac gacacgaacc gagcttccga agctctacga
   174961 gggccgcgcc acacccggaa cgctgatctg gtgccgctcc aaccgcagcg gccgcttttt
   175021 cgaaggcgcg aaggccgcgc tccaggccgg cggccagccc aacgtcgccg agctcgctca
   175081 cacctgttac ctgatgcgca ataccggcct cgacggcaac ggtaccttcg ggacgaaatc
   175141 cttcctcgcc tatgaggggg atcacccgct tcgctggtcg ctggccgccc agatgctctg
   175201 cgcctatatg atgcgcgttt tcgcccagga tctccttgcc catctcgtcc ggctcgaagc
   175261 acccgcagcc ccgcggatgg caatcgagct tcgccgcttc ctcggggtcg gcaacggctc
   175321 ggcgcttggg ctgatgctct tcgtcaacaa ccacccgcgc ctgatcgagc gctggctatt
   175381 catccgcgaa gaggcgatcg cccgtgcaaa agggctcaca ccggatgaaa acggctcgga
   175441 gatcgccaag ctgttgagcc ttgtcgacaa agcgataacc ttccggtccg aggaccgcgt
   175501 gcaatacgag aacgtcacac gctccgacgt cgtggcacga gaactcggca tcatccgcag
   175561 cgccgtcgcg aaattgctgg accgttggcg gagcggcagc cgattcgaaa gcgagccctt
   175621 tgccgaactt accgcctccc tcgagtgccg cgtccatgcg gaagccatgg aaaccctcca
   175681 ttcgctcctc atagagctcg ttgccgaaga ggccgaccag ctggtggaag gcctcgtcat
   175741 cgatgaggag ctcacgggcc ggccggaaat gccggtcgcc cggctgcgcg agattctgag
   175801 aaacgattac gcctgggcgt tcgggctcga tctcgatatc gggtcggaaa agcgatacgt
   175861 ctggtacaaa tcggtttccg ccgaggagcc acgccgcggc cccgttgccg aagtcggcga
   175921 gaacgtcgtc aatcttggcc tcgacctgcc gcggctcgtg gtgtcccttg accgcgacct
   175981 cgccgccgcc gatccgaccc tcagcaccgc ccgcttcctg cttgctcgcc ccgaacaccg
   176041 ggcaatcgcc acccgcgtgc aggctcttgc cggcaccggc ctccattcgc cgcatgccga
   176101 tatcatgagt gaacacttta cccccgccca tatcacccgc cttctcaatg tcggcatcca
   176161 cggcatcgac aagacccgcg atttcctcga ccgcaacctg cgcggcgttc tgttccacgg
   176221 cgcgcctgtt ccggaagaca ttgccgccgg cagcgccgac gacctgtggt tctacccttc
   176281 ggagccgagc ctatgagttc ctgccagtcc aaccttcctt cgaccctcac cgtcagtctg
   176341 cgtgaaatgc ggatggtctt tgagcgactg gtacaagtcg cgcgtgtcga cgcgggcctg
   176401 gtgccctccc tcagggattg cgccctttat tccgcggccc tcggcctcgg cggcttcgcc
   176461 cgtctgctcc acaaccttga ggcggtgcga tcggcaaatc cgcatgtgct gagcctgacg
   176521 gcagatggcg agcgtctcat cgtcgactgt ggcgggcagc acgcgtggat tgccgccgat
   176581 gcggtgctcg atctcgcaac ggagcgtctg cggacgcagg gcgcaggtac aatcacggtt
   176641 cgcaccgcga ccgaggtgga cgaactgaga gtcgtcgagg ctcttgcgca gcgttttggc
   176701 ttgaatgccg aggtcgctat cgacgggacc accggctgtg ccgagatcgt cgtttcgccc
   176761 gccgcgaagg aaatgcatcc gacggttctc gaaagaatcc ggcgcgacgg gctgaccgtc
   176821 gatgcggctc tctggtggca gctctttcac cagtccgccg aagcgctggc gcccgattcc
   176881 tacgtatcgc gccgccacgc cggtccaatc attgtcgagg cggacggtaa ggtcatcggc
   176941 cggcaggacg aggatgagac ggacctctct ctgctcatcg ccggcgccga aaagcacggc
   177001 acgacggcaa tcaataactg agatggaacg accatgatta tcgatgcact tcaatgtggt
   177061 catttcgacc gcgggtcctt cgaggcgcta aggcggggcg gctacagtgc ggtgacgccg
   177121 acgctcggct tctgggaagg gacgatggag tctctcgact cgcttgcccg ctggcgagac
   177181 atggagcgcg agaacgccga cctgatcctt attgccagga ccgctgccga catcgagcgc
   177241 gccgaaacgg aaggcaagct ggcggtcgtg ctcggctacc agaactcgaa cctgttcgag
   177301 gaccgcatcg ccttcgttga attcttcgcc gagctcggcg tccgcgtggt ccagctgacc
   177361 tacaacaacc agaacgaact cggcggctcc tgttacgagg agaatgacag tggccttgct
   177421 cggttcggcc gcgatgtcgt acgggaaatg aaccgcgtcg gcatgctggt cgatctctcc
   177481 catgtcggcg accggacgac tctcgacgcc atcgaatggt cggaaaggcc ggttgcgatc
   177541 acgcatgcca atgccgcttc gctttttgcc cacaagcgca acaagtcgga caaggtgatc
   177601 aaggctcttg ccgaacgcgg cggtgtcatt gggtgcgtcg cctaccggaa catcacgccc
   177661 gacgccgcct gcgccaccgt cgacggctgg tgcgagatgg tcgcccgcac cgtcgacata
   177721 gccggcatcg accatgtcgg catcggcacc gacatttcgc acaaccacac cccgcgcgac
   177781 tacgactgga tgcgcaaggg ccgctggacc cgctcggttc agtatggtgc aggctcgccg
   177841 gagcggcctg gcgcggtggc gaagccggaa tggctgctca agccggaaaa cctgcaggat
   177901 gtcgccgcgg cactgctgcg cgccggcttc aatcaggagg aagcgaacaa gatccttcgc
   177961 ggcaactggc tccgtcttta cgcggaggtt ttccgtccga actgaccgga accaaaaacc
   178021 ggattcaaag aacaagaaga gccgccgcta taggcgagcg gccgcgggaa tagcagtcaa
   178081 acgaccattc gacatcaagg agaaccacga atggaaatgt tcaagaatgc atcagccacg
   178141 ccgctatcgc gacgtgccgt tctcggcgcc ggacttttcg gggccgcaat gctggcttcc
   178201 ccctctatcc gacgcgccag cgcggaggag aacgcccttt atgtcaacac ctggggcggc
   178261 gactgggagg catcggtcaa gaagttcctg ttcgagccgt ttacggcgga tacgggaata
   178321 gagatccgca cagtctcgcc gatttccttc gccaagctcg cggcgcagaa gaccacgggc
   178381 gtctacgagt tcgacgtcac cacgctcggc gtcgcagacg tcgcgcgcgc caatggggcg
   178441 ggcctactcg agacgctgga aggtcacgtc gacacctcca agctttggga aggcgccatc
   178501 tacgaaaacg ggctggcaac gcatggcttt gccacgcaga tggcctacaa tgccgctaaa
   178561 ttccctgaag ggctgaagaa ctggtccgat ttctttaacg tcgagaagtt cccaggcaac
   178621 cgcagcctgc agcgtcacgc cgcccgcgtc ctggcgatcg cgctgcttgc cgacggcgtt
   178681 ccggccgacc agctcttccc ctacgacctc gaccgcgcct tcgcctcgct cgaccggatc
   178741 aaagaccatg tccgcgtctg gtggaccgcc gggccgcagg cgcggcagat cctgaccgac
   178801 ggtgaagtgg acatggcggg gctctgggat agcgacgcct tcggcgccaa ggaggcttcc
   178861 aaggagccga tcgaaattgt ctgggaccag gccgtcgtcg acaaggcctg ctggatcgtc
   178921 gccaaggaca gcccgcgtgc agaaaacggc ttcaagctga tcagccatat cggccagaac
   178981 gccgaggggc tcgcaaagtt ctgcatcgcg gaccagaacg gtccgatgaa cccgaagtcg
   179041 ttcgatttca ttccagccga ggtcgcggcc agaatgccga cccatccgga gcacctcgcc
   179101 cgggccgtca tgctggacgg ggcgaagctg ctgccccagc tgcacgagct gtccacccgt
   179161 ttcgaaagct gggtcggtat ctgagcccac tgccggttcc ggtaagaacg gctggaaagt
   179221 gcaatgcatc ggatagggtg ccggcagtgg ctgcgccggt accccgcttt cgcggcaaaa
   179281 accctgtccg agggtaaagg agcaatgtca tgaaactccg gacgtccccg gtcttcgtgg
   179341 aagggcctat gccgctgata gctccggcgg tgatgttcct ttcactcttc tttctcgttc
   179401 cgcttggcta cgtcgtgtgg atgagcctgt cgcagccggt catcggactg cagaatttcg
   179461 gccggctgct gaattccagt ctgttcgcgt cggtccttta cagcacgttc aagacggcgc
   179521 tcctggtaac gctgctgagc cttctcttcg cctatccgct cgcctatgcc gcggcgaacg
   179581 gctcgaagcg ctttgcaacc ttcctgctga cggtcgtcgc gctctctttc tggaccagct
   179641 atctggtgcg cacctatgcc tggatggtca tcctcggcaa tcaggggccg gttaccgcgc
   179701 tcctctcgtg gctcggctgg gatcccgcgc cgaagatcct gttcaccaca ttcagcgcca
   179761 ccctcgcaat gacccacgcg cttattcctt tcatgaccat gtcgctcttc gccgtgatga
   179821 aacggatcga cccgctctat gtccgcgctg ccgaaaatct tggcgcgcat ccccttcgag
   179881 cctttgtttc cgtctatctg ccactgagcg cgcccggcat cgtcaacggc tgcacgctcg
   179941 tcttcatcac ctgtctcggc ttctatgtca tgcccgtcct gctcgggagc ccacgcgacc
   180001 agatgatcgc cggcatcatt ggcgaccaga ttgaacagac cctcgacttc ggcctcggct
   180061 cggcgatatc gatcgtgctt ctggcgctga cgctcgcggt atatgcggtc tacaaccgct
   180121 ttttcggtct cgaccgcctt tgggcaggag gtgaccgatg aacgtctgga ttcgttcgtt
   180181 ggcgattttg atcgccgcct ttgtcgcggc gccgatgttc atcgtcattc cgatgtcttt
   180241 cagctcggcc gcgtcgctag ccttcccgcc acccggctat acgctgcaga actacgtcaa
   180301 cttcttctcc gacccgaact ggacgcagcc gctgacgaac agcctcctga tcggcctcgg
   180361 tacggtctgc atgactatgc tcgtcgccgt tccggcttcc ttcgcgttgg tgaggcacgt
   180421 gttcatcgga cgcacggtct tcaatcttct gatcatgctg ccgatgatcg tgcctacaat
   180481 cgtcatggcg atcggctatt acatctattt cgggcagctc cgtctggttc agagctatct
   180541 cggcgtgatc ctcgcccata gctgtatcgc cctgccgatg tcgacgctga tattgacggc
   180601 agcgctcaag ggcttcgacc gctcggtgga gcgcgccgca atgaatctcg gtgcttcgcc
   180661 gttcacgacc ttccggctga tcacctttcc gatcctgcgg ccagccttca ccgttgccgg
   180721 gctcttcgcc ttcatcgcat ccttcgatga ggccgtcatc ggcctcttta tttccggccg
   180781 cgacaaggcg accttgccgc gccagatgtt caacgccgtc cgtcaggagg cggatccgac
   180841 catctcggcc gcttcttcct tcctgtttct gctggttctc gccggcgtct gtatctggct
   180901 cgcgccgcaa ctcgtgcgcc gtcgcacgcg ccttctgggc cagactgacg gcaacggcgc
   180961 agcacagccg gccgccgcga catcctgatc ttggagcata gccatgaatg cccgttccct
   181021 cacgctcagc aacatcacca agacctatga cggcaggcat atggctgccg acgacgtttc
   181081 gctcgacatc aaggccgggg agttcgtctc cttcctcggc ccgtccggct cgggcaagac
   181141 cacgacgctg atgatgatcg ccggcttcca gcacccgacg agcggcgaga tccggctcgg
   181201 tgagcgcgcg atcgacaacc tgccgccgca caagcgcaat atcggcatgg tgttccagaa
   181261 ctatgcgctc ttcccgcaca tgacggttgc cgacaatgtg ggattcccac tgcgcatgcg
   181321 cggcgtcgcc aagcaagaca aggagcgccg ttcccgcgag gcactggcca aggtcgggct
   181381 gcagggtttc gaaaaacggg tgccctccga gctctccggc ggtcagcagc agcgcgtggc
   181441 gcttgcccgc gcgctcgtct tcgaaccgga catcatcctg ctggacgagc cgctcggcgc
   181501 cctcgacaag gctctgcgcg agcacatgca ggtggaactg aagcgcatcc acaaggacct
   181561 cggcgtcact atggtctatg tcacccacga ccagtcggag gccatgacca tgtcagaccg
   181621 catcgccgtc ttcaatcagg ggcggctcga acaggtcggc accccgaacg agatctatcg
   181681 cgcgccgaaa acccgcttcg tcgcgtgctt catcggcgac agcaacctca tcgagggctc
   181741 cgcgctcggc ggcggaagat tcgacacgcc ggtcggcatc gtcgaggcgc ggagcagcca
   181801 aacggaccga aaccgccggg ccgatctgct gctcagaccg gaaatgatcc gcatcgccga
   181861 gacctcacaa ggcgggcgcc agccgttgaa aatcgacagc accatcaatt atggcgacaa
   181921 cctgctcgtc atcggcaagc tcggctcaca ggcgatccgc atgcgagttc ccggcgcgga
   181981 cgcgcgcagg ctcgaaggcg tttcggaatg ccacgtgacc tggcgcgccg aggatgtcca
   182041 cgtcatcgcc tgatccgaac tccgattgcc gatggagccg cacatgaacg accgtccaaa
   182101 ctctctccat gctctcgaca agcagagcct cgtccacccc tacacgaacc tggccgtgca
   182161 tcaggaaacg ggaccgcacg tgatcaccgg cggcgatggg atctatgtcg tcgacgacga
   182221 aggcaaacgg tatatcgagg gactggcggg cctgttctgc gccggtctcg gcttcagcga
   182281 acagcgcctt gtcgaagctg ccatgcgaca gctcaagacg atgcctttct atcattcctt
   182341 cgcacacaaa tcgacagagc ccggcatcag gctggcggag aaactgctgt cgatcgcgcc
   182401 cgtcccgatg tcgaaggtgt tctttgccgg ctccggttcc gaggcgaacg acacagcgat
   182461 caagctcatt tggtactaca acaacgcgct cgggcgaccc gacaagaaga agattatttc
   182521 gcgccgtaag gcatatcacg gcgtcacagt cgcgaccgcg agcctcaccg gcctcccgtt
   182581 caatcaccgg gatttcgacc tgccgatcgc taacatcctc cataccgatt gcccgcacta
   182641 ttggcgctcc gccgagaccg gggagacgga ggaagacttc gccacgcgta tggccgacaa
   182701 tctcgaagcg acgatcctcg aagagggtcc tgaaacgatc gctgctttct tcgccgagcc
   182761 cgtcatggtc tcaggcggcg tcatcacccc gccgaaaacc tatttcgaaa aggtccaggc
   182821 ggtcctccgc aaatacgata tcctgcttgt cgccgacgag gtgatctgcg gtttcggtcg
   182881 cacgggcaac atgttcggct cagagaccta cggactcaag ccggacatga tcagctgcgc
   182941 caagcagctg tcggccgcct acatgccgat ctccgccctg atgatcaacc agaagatcgc
   183001 ggacgcactt gtggaccaga gccggaagat aggcactttc tcgcacggct tcacctatgg
   183061 cggtcatccg gttgcagccg ccgtggcgct gcaagcgctg acgatctacg aggagatcga
   183121 tatcgtcggg catgtgcgtt ccgtcgcccc cgtctttcag gatcgcgctc ggaagctcgg
   183181 cgagcatccg ctgatcggcg aagcccgcgg cgtcggtctc gttgctggct tcgaattcgt
   183241 caaggacaag gcgaccagag agaatttccc ccccgcctgg caggtggcaa accaggccgg
   183301 caagttcgcg accgcccgcg gcgtcctgac gcgcggcctc ggcgatatgg tgagcctctg
   183361 ccctgcaatg atcattgacg aggggcagat cgacgatctc atgacgcgca tgggcctggc
   183421 gcttgacgat acgctggctt gggcacgcac acagggccat gtcgcctgaa ggagagagca
   183481 tgaacccgga aagcaccgca cccgcctatg ggcgtctcgg catgctgatc gatggccgct
   183541 gggtctatga ggcggagggg agcagcgacg tggtgaatcc cgcaacgggt cagacgatcg
   183601 cacggctgcc gcacgcatcc gatagcgaga tcgccgaagc cgtcgcgtcc tcgcagcgcg
   183661 ccttcgagag ctggaaggat cgctctccgc tcgagcgcag ccacatcttg cgccgcttcg
   183721 cagacctcgc ccgcaagcac gccgaggaga tcgccgccaa tatgaccctc gatcagggca
   183781 aaccgctcgg cgaggcgatc ggcgaggtcc gatttgccgc cgatcatgcc gactggcacg
   183841 ccgaggaggc ccgccgcacc tacgggcgga tcattccatc gcgcgaccca cgcgtgcagc
   183901 agatggtcgt tcgcgaaccg gtgggcgtct gcgtcgcctt caccccttgg aatttcccct
   183961 tcagccaagc gttgcgcaag gtggtggcgg cgctcgcgag cggctgcacc atcatcctca
   184021 agggacctgg ggaatctccc tcttccactg tggcaatcgg gcggctgatg caggaggccg
   184081 gtctgccgga cggctgtctc aacatcgtct ggggcgaccc ggctcacctt tcggagtcat
   184141 tgctgggggc gccggaagtc cggaagctct ccttcaccgg ctcggtcggg gtcgggaagc
   184201 atctcgcgag ccttgcaggc aagtacatga aacggtcgac gatggagctt gggggtcatg
   184261 caccggtgat cgtctttgac gacgccgaca tcgaggcggc agccgacgcg cttgcgggcc
   184321 agaaggtgcg caatgccggc caggtctgca tctcgccaac acgcttctac gtgcaggcga
   184381 aagagcatga ccgtttcctg gctcgcttta ccgagagaat cgcttcgaca aaggtcggag
   184441 acggtttcca ggagggggtg cagatgggtc cgctctgcca cagtcgccgc ctggctgcca
   184501 tggaggattt cgttcaggac gctcgcgagc aaggtgctac aatcgttacc ggcggcgagc
   184561 gcattgggaa tgccggattt ttctatgcgc ccaccgtggt cgccggcggc accgatgaac
   184621 tgcgcctgat gaaggcggaa cccttcggac cgattgccgt cgtcacgccc ttcggcaatt
   184681 tcgacgaggt gatccggcgc gccaacagcc tgcccttcgg tcttgcttcc tatgtgttca
   184741 ccgcttcgag caaccgagcg cagcacgctg cccaagctct tgccgccggg atggtaagca
   184801 tcaatcattt cggccttgcc ctgccggaaa cccccttcgg cgggatcaac gacagcggct
   184861 atggcagcga gggggggtcg gagacactcg acggctatct gaacaccaag ttcgtcaccc
   184921 gattcgacca gatcccgcag tgaacctgtc cgaccagcga aacgacaagg aagatcatgt
   184981 ttgaagtcat tgataccggc gccgatccat cggacgttcc cgtcagtgaa gcggttcggg
   185041 ccggcggtct cttctggtca gtgcacgtct cggaggatcc ggtcaccggc gagccggtct
   185101 tcggcgacat cgaaacgcag gcacgcagaa cgctgcaaaa cctggaaata gcgatcaggg
   185161 ccgccggcgg ctccctcgca aatgtcgtgc agatgcaggt gttcctcact gaaagagccg
   185221 acgctcccgg catgaacagg acctatacgg agttcttcag ggagccctat ccggtgcgcg
   185281 cgaccgtggt cgtgaaggag ctcatcaccc cgggcttgcg catcgaggtg cttgcccatg
   185341 cggtgctcga cagtgcctga tccgagcgca ggttccgatt tgagcaaagc gggaggagca
   185401 cgaatgttcg agaaggtcga aaccgggatt accgcatccc gcgccccctt gagcggcaca
   185461 gtgaaggcgg gccagatcgt gagatcggtt cacatagcaa agaacccgga gaccggcgaa
   185521 ctcgtcaccg gggacatcga atgtcaggcg cggcaggtct tctccaacct ccgacaggcg
   185581 ctggaagcgg ccggaagcac gcttgccgct gtcgcgcaga tacaggccta tctgatcgat
   185641 agggccgacg ccgccggcat gaacaaggta taccgtgaat tcttcacgcc tccatatccc
   185701 gtccgggcaa ctgtcgtcac ggagctcctt tcccccggta tacgccttga aatcctggcc
   185761 acggcggttt gctccaggga ttgagcgttt caagccgtgg agcgggatga ggaaaagtgt
   185821 gtgcggtttc cgccggcgtc ccgctctatc tctttgaaat cgattacgtt catgttttca
   185881 gatcgatccg acctaaaaac attgtgatct ggcgaaggct gactgcgctc cttgctgctg
   185941 cagcggggat ccgtcgccgc atctgacacc gttgtgagca gccacctacc gggcgtggcg
   186001 gatccgccat ttgcaacaaa tcccaagatt tcagaccacg cgtcttgacc ggcaaactca
   186061 tgtggtgctt actggtatta ccagttggaa ccatttgcat gaaccctgtg ctttcagaca
   186121 gtgccgacga acttgcggga accgaaaagg tgctctcatt cttccgggaa cagcttctgt
   186181 ccggtgccct caaagtgggc gacaggctgt tgggcgagcg ggagctctgc ctggctctgg
   186241 gcgtgtcgag gccggtgctg cgggaggctc tgcgatcgct cgccaatctg ggctttctcg
   186301 acatccgtca cggtaagggc gccttcgtgc gcaaggccga cgtgggtgta ttcggcgatt
   186361 ttctgacatt ttgcctggct cagcagcccg acatgctcga cgacatcatg caggctcgtg
   186421 tcgcgatcga atgccaggcc attcgccttg cctgcatccg ggccacggac agcgatctct
   186481 cacgtatcgg cagtctgctg acacgtctga tggagacgct ccacgacgcg gaagacggtg
   186541 gtgccgcgga cttcgccttt cacatggcga tcgtcgaggc cagccgcagt ccagcgctca
   186601 ccacggttta ccgctcgata tccgaccttc tgaagcgcag ccatgtccag cggcgcgccg
   186661 agacgagcga tgcgcccgga atcaccgatt atctcgtgga agcccatcgg gaggtcttcc
   186721 tgtccattct cgcgcgtgat ccggacaagg ccgacaggat gctgcgcgaa catttcgcca
   186781 tcggcgacga gcttcggcgc aaaagctaca tagctgcctt caccaggaag gatgcgccgc
   186841 aggaagagga aaaagaagca gacagctaat tttatccagg gaggaggaga gcatgctgaa
   186901 ctttctgaaa catggccgga taaccggcgc catgctgggg gccgctttat tgacaggcgc
   186961 cgcctcggca accgaattgc gctatgcgca tgtgggcgcc gagggagaca tccagacggt
   187021 ttacgccgca caggcggcgg agggaattgc ggcggcgacc ggcggcgaag tcaccgtcac
   187081 cgtctatccc gccagccagc tcggcggggt cgcggaaatg gtggatggcg tgcgcatggg
   187141 ctcgatctcc atgggccatc atgattttgc ttccctcgcc cgactggtcc cggaggtcgc
   187201 cgtcttcaac gcgcctttca tctatcgcga cggcgcacat gcgctcgctg caacggaccc
   187261 gcagacatcg ccggcactcc aggcgatcaa cgagaagctg gtcgcacagg gcgtgcggat
   187321 catcgggcgc atctatcgcg gcgatcgcca catttcctca aattttccgg tgaagactcc
   187381 cgcggacctt gccggaaagc ccttccgtgc cgtcccgctc gaattgtggg tttccatggt
   187441 caagggcttc ggcgcaattc ctaccccggt cgaggttgcc gaactcccga ccgcgctgat
   187501 gacgggcgtg gtggtcggtc aggaaaaccc gctgaccatg atcgcctcca acaatctcaa
   187561 cgaggtgcaa tcgcatctgt caatgaccgg ccacatgcgc gccgtgctcg ccgtcttcat
   187621 caatgaggac gtctggcagg gattgagtga agagcagcgc tcggccctca ccaaggtcct
   187681 cgacgaggag gcccggaaat cgctgaagat ggcaacggaa tcagaggccg atctggtgaa
   187741 ggaactcaag ggccgcggca tgaccgtcat aacggaggcc gaagggctcg acgtggcggc
   187801 gttccgtgag aaggtcagcg cccagatcag acaggacttc cccgatttcg cgccgctcat
   187861 cgagcagatc gaggcggtga agtaagccaa gaggctgcag ggacaggcga ccgccgctcc
   187921 tgtccctgca aattccactt caagaaagaa tgggagggag aagatgcgtt tgcccgaacg
   187981 tgtcctgacg atcgtcgtgg ttaccgtaat gtcggggctg atcatcgttc ccacggctca
   188041 ggtcataatg cgtggcgtct tcaggctgcc tttcatcggc gcggaggaat tgacgcgctt
   188101 cctgctgatc tgcctggtgt tcctttccta tccgcttgtg gtcgggcatg gcgagaacat
   188161 cgtcatgggc gagctcaagg cggccatgcc gaagaaagcg cgcgcaatcg tgaatgtcgc
   188221 gatctcggtc gtcgccatcg cggtaaccgg cttcatcggc tgggtgaccg cgtcgaacat
   188281 cacccggaac ctggccaatg ccaccccgac gctcggcata ccgttctgga tatttctggg
   188341 cgcgacgctt ttcggcttcg cagcagcggc gctcatccat ctgctccacc tgcgcaagcc
   188401 gccgcaggcg gacaaaaacg tcgcggtctg agaggtcatc gacatgggtt ttctggtcgt
   188461 cctggccttt ctcggtctct tcatgatcgg cttcccggtg gtttacgcca tcctgctgcc
   188521 gtccattctc tatgttcttg tcgagggatt gcccttcggg ctgcttgccc agcggatcac
   188581 ctatgcactg gactcgtttc cgctggttgc cgtgccgctc ttcatctttg tcggaaacct
   188641 catgaatctt tccggcatca ccgatcgcat cttccgcttc gcctatacgc tggtcgggcg
   188701 ggtgccgggc ggcctcgccc aggtcaatgt cttcggaagc ctgatctttt ccgggatgtc
   188761 gggggcggct ctggccgaca tcggcggatt ggggcggatc gaaatcgatg ccatgaagaa
   188821 gcgcgggttc gatccatcct tcgccggtgc ggtaactgct gcctcggcaa cactcgggcc
   188881 gatcttcccg ccctccatcc cgctgattgt gtacggatcg gtcacaagcg tgtcgatcgt
   188941 tcagcttctc gttgccggca taatgccagc cgttctctgc acggccctgt tgatgctgac
   189001 cgtgctgatc gtcgccattc gccacggcca tgcgcgcgca gaacgttggc ccacggctgg
   189061 cgagctggtc gcttcgctgg tgccggcgct gccagccatt ctcgctccgg tcctcatggt
   189121 cggcggaatg acggcaggcg ccttcacgcc gacggaggcg gccgccatta cggccgtcta
   189181 cgtgatcttc atcagcgccg ctctctatcg cgagctgacg ccggcgcatc tatggcattc
   189241 ggcggtgctg accgcgcgca gttcaagcgc gatcctcatc atcgtcgcct ccgccgcgct
   189301 tttcggctgg attctggcgg tcgagcaagt gccgcagacc tttgctgcca cgcttcttgg
   189361 ctggtcgaag gatccgctga tgctgctgat catcgcaaat ctgatcttct tcatcgccgg
   189421 catgttcctc gactcgacga ccgcaacgct gctcctcgtt ccgatcatcg ccccgccgct
   189481 cgtcatggcc ggagtcgatc ctgttcaact cggcattgtg acgatcttca acctgatgct
   189541 cggcctgctg acgccgccga tgggtctgtc gctgtttctc gtgtcggata tcgcccaggt
   189601 ttcgatccga cagctgctgc gggcgcttgt gcctttctac attcctctgg tgtccacact
   189661 cgtcatcctt accttggcaa aagacctgac gctgtggctg ccccgtctga tcgcccaata
   189721 atcattttcc caggagacac tcatatgcgt atcgtcatcg gctccgacca tgccggcttc
   189781 cccctcaagg ccaccattat cgaccacatc gtctcgctcg gccacgaggt tcacgacgca
   189841 ggctcttacg acccgagccc cgtggatttt cccgacatcg cgaagacggt cacctcttcg
   189901 atcatagacg gcaaggcgga tcgtgggctg atggtctgcg gcactggcgt cggcgcctcg
   189961 atcgcggcga acaaggtcaa ggggattcgc gcagcggtct gccatgacgt gcattccgct
   190021 catcagtcgg tagaacacga cgatgtcaac gtcatgtgca ttggcgccca gatcgtcggc
   190081 gcatggctcg ccaaggacct agtcgcagcc tatctggctg ccgaattctc caccgacgaa
   190141 gactttcgac gccgcgtgcg caagctggcc gaaatggatg agcagcgctg atccgccccg
   190201 cgccgttcgg ctatgagtcg tgcaagctat tcttccttgc tgacctcgcc gtccacaagg
   190261 tggattctgc ggtccatgcg cgcggccatg ccgaaatcat gcgtcacggc gacgaccgtc
   190321 ttgccgcgtt cgcggaccag accgtcgagg attgcaaaca cctgctccga actcgtgctg
   190381 tcgaggcttc cggtcggttc gtcggccagg atcagcggcg gatcgttggc aagcgcccgc
   190441 gcgaccgcca cacgctggcg ctggccgccc gagagctgat ccggccgctt gtcgagatga
   190501 tcgacgaggc cgagcgagga cagaagctcc gtcgcccgcg cccgcatttc gtcgcggccg
   190561 agacgggcga ccttacgcat agggatctcg acgttttcgc gggcggtgaa ctccggcagc
   190621 aggaaatgga actggaaaac gaaccccatc gtggaaaggc gggtttccgc ccggctcgtc
   190681 tcgctcatag gctcggtgtc ccggccgcgg acgcggagca tgcctcgcgt cgggcggtcg
   190741 agtagcccca gcaggtagag gagcgacgac tttcccgatc cggagaggcc ggtaacggct
   190801 acgaactcgc cctctcctat cgtgaggtcg atgtccttca ccagcgttac cggaaccgtc
   190861 tcttgcagga tacgcgtgag gccatgtgcc tcgatgagtg ggctcatgtc gctcccctta
   190921 tgatgtccac cggattaaca cgggcggcgc ggcgggcggg cagatagcct gcgacggctg
   190981 ccgacgcaag ggcgaagcct gtcgctatgc cgtagtgaag aacgctccat gcaatcggca
   191041 gcctggtcat ctcctgcccg gtcgcggcga tttcgaaacg gacctgggaa agcgcgtagg
   191101 ttatcgcaaa tccgagtgtc cagccgagaa gagaaccggc aatgccgatc gccagcccct
   191161 cgatgacgaa cagacggcgc atgtcggttt cagaaaagcc cagcgacttc atgatcgcga
   191221 tgtcgcgcgc cttctcgtgc gtaatggtag acacgatgtt gaaaatgccg aagcccgcga
   191281 ccagcatgat cgcggcgaca acggtgtaca tgatcacatt gcgcacgacg agcgcctcga
   191341 gaatggactc gtttgcctcc tgccaggcga cagccttgta accaagttcg acctccacgc
   191401 gatgcgcgat cgaaggcgcg gcattcgggt cgtcgagctt gatgcggatc tcgttgattg
   191461 cgttcggcct gttggacagg atttgagcgt tcttcagcag gacatagccc tcgccttcgt
   191521 cacgtgcggt agtacctgta tgaaaaaggc cgactatctt gaaattgcgg gcgcggcctt
   191581 ccgacgatat ggcagtgatc gtatcgccga gcgcggctcc cagcctcgag gccatggtgt
   191641 cgccgatcac gacgttgttg ccgccggccg ctagggcgga gaaactgccc gactcgaaat
   191701 cctcgacgat gggcgagacc ctcatttctt tctccggctc gatgccgatc accacggcgc
   191761 cgacttcgcg gccggagtag cggatgacgc cttgcacgtt gagcaccgcg gcaagcctgc
   191821 ccggcatcca ctcctccagc caggagaccg cttttgtcgg attgatgatg ccgcgtcggt
   191881 cgtcccgcgg cctcagccct gatatggcaa cggcttcgaa gaggtcttcc gccggctgcc
   191941 gccgcgccgt acgttgttca tcggtcacgt cgacatgcgg catcgtgtcg acgagctggc
   192001 gcacgaaatc gtcttgcccg ccttgcatca gcgccgccat cgcgatcgag aaacccacgc
   192061 cgacggccac gccgatcacc gcaaccaggg tctggcgacc gcggccggcg acatgcgtca
   192121 gggcgatgtc gaagatcagc cgcatggcac tcatttcgcc tctgttcgca ccacatccac
   192181 ccgcgtgccg tcggcaagat cagggggcaa gggcgagatt attcgctccg attcctcaag
   192241 gccggagagg acttcgacgc cgttcgtgcc ccggatgcct gtcttgatct cgcgcagcat
   192301 cgccttcctg cttttgacca ccgcgacttt cgtgccgctc accgccgccg caggaatgat
   192361 cagtgcgttg cgcgacagcc ggaccacgat gttcacatcg gtcgacatgc cgattctgag
   192421 cggcgtgtcc tccggcagac ccagacgaac acggtaggtc ttcgtcacag gatccccctt
   192481 cggcgtaatg ctgtcgacaa ccgcctcaag tgcgcgctcc gggaagacat cggagcgaag
   192541 ataggccttc tgtccaacct cgacgcgggg aatatcttcc tcgttgacct cggcttcgac
   192601 gatcagcggc cgcggctcgc cgacccagaa gagaacggtc ccgagttcgg ccacttcgcc
   192661 gatctctcca tcctgccgaa gcactcgtcc ggcactgggc gcgcgcagta cgtaggccgc
   192721 gagccgtgcc tcctggccgg ctatcaaggc ttccaattga gcaacgtcgg tgcgcgcccg
   192781 gtccaccgtc tgctcgctga tcgtatttct ttcggccaaa gcgagcttgc gccgatattc
   192841 ttcttgcgca agagacaagc gtgcctgcag ttcgcccagt atcgcctgcg cctccgtgtc
   192901 gtccaaccgc gcgagcgcgt cgcccgtctc cacacgttcg ccttcgcagt tgcactgctc
   192961 gacgatccgc tcgcgcacgg tcgacgttac cttggcccag acgcggggct ctacaacgcc
   193021 gctggcatag actatctccg cggcatcacc acgctttggg gccacgactg aaaggggcac
   193081 cggccgtagg gcataccaaa aagccgcggc accgacagcg gcggctgcag caacagccac
   193141 cacatatcgc ctcatctgct gcttcgaccg cacctgctac tcctgagttc tcaccacctc
   193201 ttctcatgac aatagcatta gaccgaccgt cggtctatga tggcacggac gggcttcgcg
   193261 catcgtgccg atacgtgtag aacatacttc tccgctccag gaaaaactta tgccacgtgt
   193321 caagaaatca cctgatgtca gaacgaatga gctcatcgag tgcgcgcagc ggctcttctt
   193381 tgagcaggga tacgagaaca cgaccgttaa cgacgtcatc cgggaggcga atgtctcaaa
   193441 gggggcgttc taccactact tcgtgtcgaa ggaggcactg ctcgaggcgg tcgcctcgcg
   193501 catggcgcac cagagcctga aggaactgca ggctcttttc gaggatccca ccctcgatgc
   193561 ggtcggccag ttgaacgcgc ttttcgccgg atcgcggcgc ctgaaagtgg aaatggcgcc
   193621 acagttgaag aatacgttca acgcactttt caaaccggag aatatcgttc tctaccaccg
   193681 tatcgacgcg gcggtcagcg cggtgacgct cccatatttg accgggcttc tagagcgggg
   193741 ccacaaagaa gggagcctcg atgcacccga tccggaagcc accgcactga tgctgcttaa
   193801 tttgcggctc ggtgtcgcca agaccatgca tcgggctctg cagcagacag aagccggaga
   193861 cctggacggc gcggcgcgta tattggatgg ctggatgcgc acatacgggc ttgccgtcga
   193921 aagactgttg aaaattcctg aaggagcgat cgagataacc gaaccgggct tcgcgcgcgc
   193981 gtttttggaa gccaccgtct agaaaacgat gatcttctcc atcgctctct ggattttccc
   194041 cgatatccac cggcggtagc cctgatggat cagtagaggc gaagccttgc ctgtgctagt
   194101 ccatgagtag ccgtctcaga cgggggagga cggttagggg tcgggcgctt cagcgactgg
   194161 cctcgccggg gctgagacct ctgccgccgg caaaacgtct gacgacccct tcgcagctcg
   194221 atgcctcggc caagccgggg ctcgttcaaa aaaaggccct ggcctgtgcc ggccagggcc
   194281 ccattcattt cccaccagct ttgaaagtca gcacggacac ggcaatacag tcccccgcat
   194341 agcccattgc aagccatagc gatgctagag gatgtgtcgg tgcagaacgg atattacacg
   194401 aacgtattat aaggaccagt aacaaattag gggtattcgg caaagcgact ccgtgaatac
   194461 ttcgtttact ggcgatgatg acgccttccg cctcgacgat ctatccacgg aagttggact
   194521 taccctcccc gaacggatga gcgccagacc agattcggtt ggaagcggac cgagtcgtcg
   194581 cccgccgcct ggccgctctc gtttacaagc caagccacgg cctcccgggc gatcatctcg
   194641 accggttgcg cgaacgtcgt caggtcatac gaggaccagg ctgcctgctc tatgtcgtcg
   194701 aagcccacga cacagagctg gtccggaatg gcgacccgga actggtggcg agcggcatcc
   194761 atgaagccgc aggccagaag atccgtggca cagaagaccg catcgggacg ttcgctcagc
   194821 gtcagcaggc gctgcgccag aacgcggccg ctttcgtaat ccgtcggtcc gtggcgctcg
   194881 acccgaaccg ggagtcccat cgttttcgcc gccgccacga agccgtgctc gcgcgccatc
   194941 aggctcgggg tgcccgcctg cgaattcgca aaagcgagcc gccggcagcc ggcacgcacg
   195001 aaagcggtga cgacccggcc ggccgcttcc gcgtcatcga gattgatgcg aagcggcccc
   195061 tgctggtcgt cgtcgcgatt gatgagcacg aggcgctggc cgttcttgag gcaaagctgc
   195121 gtaatcgacc tgtcgggcat gccggacagg atgatcgatg catcggcgcg gtaccggatc
   195181 gcctggcgca gcgcgagatc gacgctgccg tcggaacggt cggtattgat cagcatcgcg
   195241 atcttaccgg cgttctgcaa ttgctgcgtc attgcgcgga tcaggttggc gcggtagggg
   195301 gtactcatct ccgaaacgat aaggcagacg atgccgctct cgttgcgcat cagcccgcgc
   195361 gcgagatgat tgacatgata gccgagcgct tccgcagcct ctaccaccct ccttcgggtt
   195421 tccggcgaga cgctcgcgcc gggcgtgaat gtgcgggaga cggctgagcg tgacacgccc
   195481 gcacgctctg cgacttcctg tgcgctgaca aacggcttct gcggcatcgc gacctcgctt
   195541 ccatcctgca cgcaggtttg caccattttg caattgcgtg caacgcggtc gcggcgttcg
   195601 ataccttaca aatttgttga caccctcgtc atcctcgtgc agcatttgca cgcgcttgca
   195661 acaacggcgc ccggcaagga ggcgccggca caatctggga ggaaaccaat gggtttggtt
   195721 aaactggccg cggcagcgct cgccgcgggc gcgacgtttt ttgcctattc ggcgaaggcc
   195781 gatggaaatc tcaatctgat ctgttcggcc gatgtggtga tctgcgaaca gatgaagggc
   195841 gccttcgaaa agaagtccgg cgtctccgtc aacatggtgc gcctctcttc gggcgaaacc
   195901 tacgcgaaga tccgggccga ggcgcgcaac cccaagactg acatctggtg ggccgggacg
   195961 ggtgatcccc atctgcaggc cgcttcggag gggctgacgg tcgagtacaa gtcgccgatg
   196021 ctcggcgaat tacacgaatg ggcggtgaag caggccgaga gcgccggcta tcgcacggtc
   196081 ggcgtatatg ccggcgcact cggctgggga tacaacaccg agatcctcaa gcagaagaac
   196141 ctgaaggagc cgaaatgctg ggcggatctg ctcgatccct ccttcaaggg cgaagtgcaa
   196201 atcgccaatc ccaactcttc cggaaccgcc tataccgcgc tcgcgactct cgtccagatc
   196261 atgggtgagg aagaggcttt cgattacctg aagaagctga acgcgaacgt ctcgcaatat
   196321 acgaaatccg gctccgcacc ggtgaaagcc gcagcacggg gagagaccgc aatcggcatc
   196381 gtattcatgc atgatgctgt ggcgcagacg gtcgaagggt ttccggtaaa gtcggtggcg
   196441 ccgtgcgaag gcaccggcta cgaaatcggc tcgatgtcga tcatcaaggg cgcaaaaaac
   196501 ctcgacaatg ccaagaaatg gtatgactgg gctctctccg ccgacgtgca gtccagcatg
   196561 aaggaggcga aatcgttcca gcttccttcg aacaagacgg ccaaggtgcc cgaggaggcc
   196621 ccgaagttcg aagacatcaa gctgattgac tacgacttca agacctatgg cgatccggcc
   196681 aagcgcaagg agctcctgga gcggtgggac cgggagatcg gcgcggccgc gaactgatcc
   196741 gcgcctttca gccgcggcac ggtcgagctg gcggaaatcc gccggctcga cgcccgcaaa
   196801 attcagcgct gtgcaggtcc gatcgcatcg cgccccctcc gacggcagca atcatccgtt
   196861 cgcctgcatg ccgggcgagc tcatcgtgac actgcggcac cggacgaagt tttcatgaaa
   196921 acgcacaatc gtagactgga tatcgtgctg gctctcgggc tcgcagcctt caccatcttt
   196981 ccctggtaca ggatcgacgg cggattcttc ggattcggtt ggctatccgg cttccccgtc
   197041 gaaccggcgg tcgcgccggg tttccttcag attgccgcct ttggcaaatg gtggctggtg
   197101 cttccggctc ttgccgttct cgccgccctc tccgttcgtt tcattggcga tgcggcgcga
   197161 cgaggaagcc tcctcgcctg ggcgggcgcc gccggtatcg tgatcatggc tcttcagggc
   197221 ctcgccatcg gtttatccgg ctggaactgg acgatcagcg aggcgatgtt gggcacgctt
   197281 gcggacggtc agcccccgat gggcgccgga gccgtgcttg ccgcgctcgt cttcgtcttt
   197341 attttcgcct tcggactcgc cgagcggggc gtgatgaagg gcgacgcctt cgcggttgcg
   197401 tccatctcgc tgcttgtctt tctcgtcgcc gtcttcgtct tctaccctgt cggcagcatg
   197461 ctggtcggcg ccttccagga ttttgacggg tccttcaacc ccgagggctt cagccgcaat
   197521 atagtcgacc cgtcgatctg gagccttgac tgcgtgatcg gcggccggcg ctgcggcatt
   197581 gcctggcgga cgttctggct ggcggtgatg accgccggcg gctcgaccat cctcgggctc
   197641 gccttcgcgc tgctcgcgac ccgcacggca ttcccctaca agcggagcct caggcttctc
   197701 acggtgctgc cgatcatcac gccccccttc gtggtcggtc tagcgctcac gctgctcttc
   197761 ggccgctccg gcgtcatcac cgaagccatg tcgacgctga tcggggtcga gcccggccgc
   197821 tggctctatg ggctgaccgg catctggatt gcacaggttc tgtccttcac ccccatctcc
   197881 ttcctggtgc tgatcggcgt cgtcgagggc gtcagcccct cgatggaaga agcctcgcaa
   197941 acgttgaggg cgaaccgctg gcggaccttc tggcgcattt cgctgccgct gatgaaaccg
   198001 gggctggcca atgcattcct catcggcttc atcgaaagca tggccgattt cggcaacccg
   198061 cttgtccttg gcggcagcca cggcgtgctt tcgacggaga tcttcttcgc tgtcgtgggc
   198121 tcgcagaacg atccctcccg tgccgcggtg ctcgccatca tcctcctgtg tttcacgctc
   198181 acggccttcc tggcacagcg cttctggctt tcgggaaaga gctacgccac ggtcaccggc
   198241 aagggcgaca gcggcgctca cgctgccctg cctcgcacgg tttcgatcgc ggtgcatgtc
   198301 ctggtcatcc cgtgggcgct cttcaccctc gtcgtttacg gcatgattct cgtcggcggc
   198361 ttcgtcaaga cctgggggct ggacaactcg cttacgctcg cacattacgc caaggcattc
   198421 tccgtcgagc ttcgcgacgg cggcatcgcc tggacggggg ttgcctggaa ttccttttgg
   198481 acgaccatgg agatcgccct gatttcggcc ccgctgacgg cagccgtcgg ccttcttacc
   198541 gcctatctga tcgtgcgtca gaagtttgcc ggaagggaac tgttcgaatt cgccctgatg
   198601 atgagcttcg ccattcccgg gaccgtcatc ggcatcagtt atataatggc tttcaacctg
   198661 ccgccccttg aaatgaccgg cagcgcgctg atccttgtcg cctgcttcgt cttccgcaac
   198721 atgccggtcg gcgtccgcgg cggggtggct gcgatgagcc agctcgaccg aagcctcgac
   198781 gaggcgtcgc tgacgctcag ggccgatagc ttccgcacca tccgcaaggt catactgccg
   198841 ctgctgcggc cggcgatcac ggcagccctc gtctactcgt tcgtgcgcgc gatcacttcg
   198901 ataagcgcgg tgattttcct ggtcagcgcc gagtacaaca tggcgacggc ttacatcgtc
   198961 gggctggtcg agaacggcga atacggtgtg gcgatcgcct attcctccat gctgatcgta
   199021 gtgatgattg cggtcattgc cggcttccag cttatcgtcg gcgaacggag gcttcggcgc
   199081 gaaaaccgga tccaggccgt tgccggcgta cccgttcctc ttccccagga gaaaaccgca
   199141 tgaccatcgt ggctcccggt tccgtcgtct tccggaacgt gcgaaagcaa ttcggtgtct
   199201 ttaccgccat tcccgatctg tcgctgacca tcgaaccggg tacgctcgtg acgctgctcg
   199261 gaccatccgg ctgcggcaag acgacgacgc tccgtatgct cgcgggcctc gagcatccga
   199321 catcggggcg cattctgatc ggcggcaagg atgtcacgat gctgcccgca aacgaacgcg
   199381 acgtgtcgat ggtcttccag tcctacgcgc tcttcccgca tatgaatgcc ctcgacaacg
   199441 tcgcctacgg cctcgagtcc tccggaatta agcgcaatga ggcgcggcag agagccgaag
   199501 agggactggc gctcgttggc cttcccggca tgggtcagcg cctgccggcg gagctctccg
   199561 gcggacagca gcagcgcgtc gccgttgcgc gtgcgctggt actggagcct caggttctgc
   199621 tccttgacga gccgctatca aatctcgatg cgaggctgag gcgccgcgtc cgaaccgaaa
   199681 tccgcgagct gcagcagcga ctgggtttca cggccgtcta cgtcacgcac gaccaggacg
   199741 aagcgcttgc cgtctcagac cgcatcatcg tcatgaagga cgggaacatc gcccaggagg
   199801 gtgcgccgcg cgaactttac gagacgcctg cctcggcctt catcgccgat tttatggggg
   199861 aggcgaatgt cgtcgcctgc gacgtcatcc acgtggacgg ccacgaggcc acggtccgcg
   199921 tggagcagct gacgcatcgc gtgcgcggcc gcggcatgcg tcccggtccg gcgaagctcg
   199981 cggtccgccc gaacgcgatc gcgctcgagg cggcaaccgg cggcagcttc tcaggcgaga
   200041 tcacccacac ggcctatctc ggcgaccatg tcgagtacga ggtcaagacc gccgcaggca
   200101 cgcttttcgt cgtcgataca gcagtggagc gcgcacttgc gccgcaaacg aacgtggcaa
   200161 tcgccttcaa ggagcgcggc atcgccgtca tcagcggctg acccgagatc atgacagagc
   200221 gatccctcaa catttcgcaa ccaaggaatt cctgatgaca tctcacgtcg ttcccgggct
   200281 ggaagcccgc ctggcattgg ccgaaaccat cgcgcgcgag gcaggcgccg tggcgctcga
   200341 atatttcacg cgccgcgaga cgctgatcat agaaacgaag cgcgatcccc aggacctggt
   200401 ttccatcgcc gaccgggagg tcgaaacact gatccgcgac cggatcgcgg aagcctaccc
   200461 ggaagatggc gtgctcggcg aggagtatgg ccttgttccc ggcagttcgg gcttcacatg
   200521 ggcggtcgat ccgatcgacg gcaccagccc gttcgtcaac ggcatgccca actggtgcgt
   200581 ctccatcgcc cttgtccatg ccggcgtagc ggtggtggga gtcatcgccg caccgtgcta
   200641 cggtgaactc tatgcggcgg cactcgggct tggcgcacgc ctaaacggca agacgctcgc
   200701 gatcgatggc tcccggacca ttcgcaacca cgtgaccggg cttggcgcca acaactacgt
   200761 aaaacccgcc ttcgtcggaa agatggtcga aaatcttctg gaagccggcg gcaccttcat
   200821 tcgcaacggt tccggcgcac tcatgctggc ctatgtcgcg gccggccgcc ttgtaggcta
   200881 ctacgagccc tatatgcacg cgtgggattg cctcgccggc tattgcctgg tcaaggaagc
   200941 gggaggctgg tacctgccct tccccaccga tggcgaaggg ctgaccaagg gtgcagcggt
   201001 gcttgccgcg gcacccggcg cagtcgagga cctgagaaag cttgcaggca tctgacacgc
   201061 gcttctggtt ctggggcatc tgcccgccgg cgttcgggga gcgctcgcgc agagcaggac
   201121 gaggaaaagc gtgcgcggtt ttcctcatcc cgctccaggt cgagcctacc tacagcaatc
   201181 gtgcttcagc accctattcc cgcgcccccg ttgcccaagg cggccggcac gaaatcttgt
   201241 gccgatttcc gcaaaacaaa catgattgaa gagacaactt tatacgtctg tgctagtgac
   201301 gccgcatccg aatgatgtca attgggagaa taagatgcgt gaaggggcaa cacttttctg
   201361 acggagaccg gtggaaaata cctccttcag ttgtgcaagc attttgcgca taagatcgcc
   201421 gtagagcagg tcgatgactg cgccgaactg cgtttttcct gcggaacggg ttatctcaag
   201481 tcagccccgg acggcctgca catccgtgtc gtgtcggccg acgacgccga cctcgcgcaa
   201541 gtccaagcac gtcatcgaag gccacctcct gcgtttcgcg agaacgcggg accgcttcac
   201601 tggaccgatt tctaggacga cgggaagaac acaataatgg ccgccgatcg cttgacggtg
   201661 ctgtcgctcg gccgcgatgt cagtatcggg ctggggccca attatcagcg caccctgcag
   201721 ctcggcctgg tcatcgtatc ggttatctcg gcactgaccg tcgttgtggt cggcatcatt
   201781 ccgttcggga gacaatctgc gggcacattt cctgggtggc gcttagcggc ggcctgaggt
   201841 gccgtgtccc gagcggctac ggtgtcggca cggttggatg ccgccgtgcg agaactctgg
   201901 aacagagggc cggcggggcg gttgggatgc aaggcgtcgc taccaagcgc gcatctcaat
   201961 ggacgcgcaa aaattgagta gccctcaatc atgaaaggac cgtgtcatgg cgcggcaaga
   202021 cttgagcggc aaagtagtcg taatcacagg cgcttcaagt ggcttcggaa agggcgcagc
   202081 gcggcgcttt gcccgggagg gctgctcgct ggtgctcgcc gcccgacgag gaaatctcct
   202141 ggatgagctt gcgcgggaat gccgttcact cggcgctccg gcgctggcga tcgaggccga
   202201 tgtcagcgac agagagaggg tcgccaggct tgcctccgcc gcactcgccg agtacggccg
   202261 catagacata tgggtgaaca atgccggcgt cggtgctatc ggcccatttg aggacatccc
   202321 gctcgaagat caggccaaag tcgtcgaaac caacctgctc ggcacgcttt acggcagctt
   202381 tcatgcctac cgccagtttc gacagcaagg atcaggcatc ctgatcaaca tagcctccga
   202441 actcggcaga gaaaccgtgc catattacgc cgcctacacc gcgtccaagc acggggtgat
   202501 cggcctctgc gattcgctgc ggcaggaggt taagcaggcg gggcaggaga acatccacat
   202561 atgcgcgatc atgccgacgg cccatgacac gcctttcttc gatcacgtgg caaactatag
   202621 cgggcacgag gtccggccgc cgacgccgtt gcacgatccc gagaacgtag ccgatgcgat
   202681 cctggccgcg gcacgcgatc cgagcaacga ggatatcgtc ggatgggacg gggcgatcaa
   202741 gattgcggcg aagcggttcc taccaggcgc tgccgatgcg gtgatggcac gcatgatgca
   202801 caagacgcag atgggcgccc caccggctac aaactctccc ggtgcagtgc atagcccggt
   202861 tcaggatgga accgaggtca gtggaggacg ccgggccaag ggttgacgcc tttaggccga
   202921 gcggctgcgc ccttgaccgg ggattcggcg tcccctatct caactctcat ggacatgacc
   202981 gaccagccgc gcgcgcattc gaagttgaac tcgataaggc tggcgctgca aaggctggaa
   203041 cgcgggcggg atccctgggc gctgcggtgg caggcgctgc tggccatcat cgacctcagt
   203101 atcctcgcgt ttttcatcct cggtccctat ctgagggcgg gtccctccta tctcatcatc
   203161 gactatatca tcgctgcatg gatcggctgc gagctcatcg caagagcgtt tgctgctcct
   203221 tcggtcaagc gtttcctgcg tcggccgatg acctgggtgg acgtggtcat tctagggacg
   203281 ctgctcttcc ccgatctcct cttcaacttc gcattcctca gggtcatgcg catatgggcg
   203341 ataggcaaga gtccgctgct gctcgagggt ctccgccgcg cgggctggtc gcacctgcag
   203401 gaagtcgtcc gtgcgtgcct aaattttctc gtatttctct tcgtcgtaac gggtttcgtc
   203461 tacacgacgt ttttctatca ccgggaaggc ggagagggct tcgtcgacgc cctctatttc
   203521 acggtggcca cgatcacgac gacgggcttt ggagacatta ccctgccggg cgcgctcggc
   203581 aagctcactt ccgtggtgac gatgatcgtc gggatatcgc ttttcgtaag gctggcccag
   203641 gccgtggtca gaccctacaa ggtccacttt ccctgccctc aatgcggatt gcaaaggcat
   203701 gacacggacg ccgtccattg caaggcgtgc ggctacatgc tcaacatacc cgatgaaggc
   203761 gattgagccg tacgtcagac atggtccccg ttttgcggga gagatatcat tctttcttct
   203821 tggctgtctc aaccggctcg gtgatcagat ggaactcggc catctccttg gtggtcagat
   203881 agtagagccg ctcgggtggc gtttcgagag cattgatcca gagcccggcg ccgatgccca
   203941 tcgtgtctag atggcgtgca acccgggcgg tggtggattg tgcaaacgac atggcttgcg
   204001 ccggcgtcga ccggtcgtcg ccgccgccgc tgaagacctg atgcacgccg atcagcgcat
   204061 cgctagccgc gacgcgcgcc acacccccgg cgaaaacgat cggacaagac gaggcacaga
   204121 gtgccctcga ggctattttt gtatcgagct tcttttcacg gatcagtttg gatatagcga
   204181 gcgcatcctc gacagatccg cccggcgagt tgagagccac ggtcttcaca tactccccgc
   204241 gcgcttcgat ctcttgcgcg aagcgcgcag cggctccgag atcgatcgta ccctcggcga
   204301 gcaggacacc gccggaccct agttcgaacc tcatcggctg acgcaggact tcatcggagc
   204361 ttgcgggatg aaccggcgac cccttgggcg cagcctccgt caccgccgga ggcagaaccg
   204421 gactatcctc cagcatcgga tcaaaacccg gcaaccctgc attcatggcc gcgatctcgc
   204481 gcatgtcgat cagcaggaag atcccggcag ccgagagcat cacgaaaaag gcgccgcgca
   204541 tcagcacacc gtcgtccagc cgcatcagcg ccttgaaagc gtcatcgatc ctcatgcgac
   204601 cggtccttta cgcgcaccct cgggtcgagg ctggtgatgt tgttcggctc atcgccctcc
   204661 atttccaccg aatcgcctgc ctcgccgttc tggcccccat tcgccatcac cgcgcgctgg
   204721 acctccaggg cctgcagaag ctcggcggcc gtgatgcgct cggcaaaggg cagtttctcc
   204781 tcctgcctgc ggatcgcccc gtgcacggtc gcgaggatga agaccagtac gcccggcagc
   204841 aggtcaatgg aaatggcacc ggcccaggcg ggaataaaat cggccgcgta gcgcagtacc
   204901 gcctcggcgg atgaaagcgg aacgaagcgt cgctccgcca ccggcatccg acccagtatt
   204961 tcgtctgccg catccgagag aaccttggac tgcgctgcca ccgaagcccg caccgtctcc
   205021 atcacctggt cctggcgggt gacgagatcg gcatcgccgc catcggccac cggcgcgatg
   205081 aagccgaggg acaggtcgtc tgcggcgcgg cggatcgaag gcgcgatcga agtctgtccg
   205141 agcgatgtta tcacccccgt aagcgccacc acttcggagg agaactgatc ggcacgtggc
   205201 gtgaccgcac caggcgcgga taccagcgtc cgcatggtct cgagccgctc ctgtccctga
   205261 ttgaacagca tcgcgacctg ttcccgagaa gcattgatgc cgttttccag atccttcatc
   205321 tgggccgaca tctgcgacag aagctgcacc acgcttcccg aacccgtggt gccggtgagc
   205381 gcgcccgatt gccgctccga ggcggcaagc tgagcaaagc gttctgatgc gcgttggata
   205441 tcgggcagca ggctctgggc tgcaagtgcg ttctgatgcg cctggtcgag gtcggcagta
   205501 tagtcttcca ccgtctccgc gaggtgctgt tcgagcgcgg ccgaccccgc cagcgccgcc
   205561 gcgttgagcc agctggacat ggcgatgatc atggcagcac cgagggccat cacgcccagc
   205621 atggcgaccc ggccggcatg ggtggtcaca tgcggataga agcgggccat gtaggaccag
   205681 aaggcgtaga tgccgacgga gaccgaggcc gagtagatga tcgctgcgaa gaacactgcc
   205741 gtcggcgaac catcaaggat actgcggacg ccgagatagg tgtagacgcc cgaggcaagc
   205801 gccaatactg caagcgcgaa acgcgtcatg gtttccacgg ccgcaacgcc gtcattcaaa
   205861 cgttgggatg cgccgagggc catgagctca ttctccgcag aggaaagtat tccttaacag
   205921 agaatgaaga aacgggcgga ataaaggctg atggtgcggc caagagccgg atgccggaag
   205981 aacctctccc gcgcggggca gagccgtcac cgaacaagaa aggtctcgac tgcgccgatg
   206041 cctcgcaggt tctgggcaga gcgccggtcg agcgcccact gcccctgaag cgcgcgccgc
   206101 gtcgcgtccg atatctgtat gccgtcaggc acaccctggg attcgagccg gctcgcgatg
   206161 ttcaccgttt caccccacac gtcgtaaacg aaccgtagtc gtccgatcag cccggcaacg
   206221 accggccctg aatggatccc gatccgaatc cggaagcgct cctgctcggg ctccatgtcg
   206281 cgcaacgatc tcagcatgga ctttccgaga gccacgatcc tgtcggcgtg atccgttgta
   206341 ggctcgggga tcccgcaggc ggccatatag gagtctccga tggtcttgat cttctcaacg
   206401 ccgtgctgct cggtcagcaa atcgaactgt ctgaacatac ggtcgaggca tctgacaaga
   206461 tcggacggag tcagccttgc cgcaatgggc gaaaagccca caatatccgc gaacagaatg
   206521 gaaacttctt cgaagcggtc ggcgatgatc tcttccccgt tctgcagccg cgaaacgatc
   206581 tggtccggca gaatcgcgcg aatgagcgaa tccgcccgcg acttttccgc ttctatctgc
   206641 tgaagatagc ggtgctcccg gtcgagccag cgcttctttt cgagggtcga attgatccgt
   206701 gcgcgcagaa gtatcgggtt gaagggcttg gtcagataat cgtcggcgcc ggcctcgatg
   206761 catcgggcta ccgcggtgac ttcgctcagg cccgatatca tgatcaccgg gatgtgctgc
   206821 catcgcccct cggacttcaa tcgcgaaagc atctggatgc cgttcatatc gggcatgaga
   206881 atgtcgagca ggatgagatc gaactcctct tcggccagtc ttgccagcgc ggatcgtccg
   206941 gattcggcgg tgaccacccg atggccctca cgtcgaagcc gtcgggaaag aagatcacga
   207001 ttgcttgcca cgtcgtcaac gacgagaatt ctgccgaccc tgtccggcaa tgccgtctgt
   207061 tcggctgtcg acaggagccg ttcgagcccg gccgcgtcaa tgtcgacccg ctcctccggt
   207121 tgaagcacct ctgcgacctc cccacgcgaa agactggcga tcgcgtcgac ctgcttcaga
   207181 agctcggcgg ccgccgagag tatgacctgg agatcctctg tcagcgcatg ctgctgcgaa
   207241 tcccttgcct cttcgagaat catttcggaa taaccgatta tggcgttgag cggcgtgcgc
   207301 agatcgtgac ggaaccttgc ctccgcctcc gctgctcctt ccttcagaga gcaggcagtt
   207361 ccatcgagaa ggctatcgat cagattgttc agttgccttg ctgcggcgcc gatccggtcg
   207421 atgtcgctct tggtatggag caagccgaga tcccgcgcct gctcaatcag cagttcctgg
   207481 aagctcagta tcgcccgagc cgggccggcc agtcgttggg ccacgtgagc ggcgatcgcc
   207541 tggcgctgga agtcgttgat ggcggtcatc ttcgccctat gtcgttagca gctgctcgat
   207601 cttgcggaca agctggggca agtcgaccgg cttgctgtcg tagtcgtcgc aaccggcctt
   207661 gagcgccatc tcccgatcgc ttgccatggc atgtgcagtc agcgctatga ccggtattgc
   207721 ggatgtaagc ggatcggcct tgatccgccg cgtcgcttcc cagccgtcca tgacagggag
   207781 gctcatatcc atgaggatca ggtccggctt ttccgatgcg gcaagctcga cgccggcttg
   207841 tccgttctct gcgatcagca cctcgaagcc gcggcgcgac aaccgccgcg aaagcatgtc
   207901 gcgattcatt tcattgtcct ccaccagaag gattctcgtc atttgcggct ctcctccttc
   207961 ctcgtcctta gccttcggcc agttctttgc caatcaaagc gaccgatccg atctggcgtt
   208021 cgagtgcctc caccagctga gcccggctgt ttgcgccttt gttcacgact gcgaccgccc
   208081 gatcgcgcaa ccatttcagc tcgtttgcgg aaagatcttt cgaagtgacc acgacgacgg
   208141 ggatgttctg caattccggg atactctgca tttcgctcag cgtttggaat ccgtccattt
   208201 ctggcatcag caggtccagc aggacgagac gcggcagaag ccgcttcatc atctccagcc
   208261 cgcggacgcc gtcgcccgcc tcgtgtacgg tccatttcct cttgaccaga atgcgccgaa
   208321 ggaactcgcg tgagccctgg tcgtcgtcga tgacgagaac gtcgtgtttg ccgcccccga
   208381 atgtctcgat tgtccggaca agtttgtcag tatcgatggg cttcgtcaga tattcgaccg
   208441 cgccgagcga aagtcccagc tcgcgatccg ccaggatcgt cgccaggatc accgggatcg
   208501 tgcacaattc gggatcgttc ttcaaagcgc gcaggaccga ccagccgtcc tgatgcggca
   208561 tgatgatgtc gagaatgatg gcatcgggcc gatgctctcg ggcggcggcc aggccttctt
   208621 gtccgtttga tgcctcgatc gcggcaaggc ctgcttctgc cagcgccttt gcgatgagat
   208681 tgcgcgcagc cggttcgtcg tcgatgatga gtgcggtgcg tccggaccga acctgcgctg
   208741 cctgctcggg tggtgggcga tccacctcgc tctcgcactt cgcgggcact tccatcgtga
   208801 ataccgagcc ttttcccgct tcgctctcca ccgtgacgac accgcctatc aagcgacaga
   208861 agctgcgcgt gatgctcaga cccagcccgg tgccgccata gtttcgggtg gtcgaggcat
   208921 cggcctgggt gaaggcgttg aagagcctat cctgctgctc cggcgtcatg cctatgccgg
   208981 tatcggagac ttggaacacg agccagtcgt gctccgctct ttgttcccgc cgtaccctca
   209041 ggatcacccg cccgcctttc gtgaacttgg ccgcattgct gagcaggttg aagaggttct
   209101 ggcgcaattt ggtctgatcg gaatgcatct tgccgagatc gtcctcgaaa tcctgcgtga
   209161 acgcgtttcc attcctggcc atcagcggcg cgactgttgc ggcaacatca cggagcaact
   209221 cggcaagact gaaggtctcg aggaaaacat ccatcttgtt cgcctcgatc ttcgacagat
   209281 cgaggatgtc gttgataagc gtgaggaggt gccgtcccgc cgaggctatt ttgtcgaggt
   209341 ccggcacgag ctcctcttcc ttgtgatcgc gtgcctcctc gatcagcatt tcgctgtagc
   209401 cgatgatcgc gttgagaggc gtgcgcaact cgtggctcat ggaggcgaga aactggctct
   209461 tggcctcgtt ggccgattcc gcatggcttt ttgcgcgttc cagttcgacc tgccgctgct
   209521 tgagttccgt gatgtcggtg tagacggcca ccgttccacc atccggaatt ttgcgtttgc
   209581 tgatacgaac ccatctttcg ccaaaccgct tctcgtcgac gaggcccgcg ggatccctat
   209641 gaagccttac gcgctcgtcg acccactcct gcggcgactt tccttcgagg tccacctgcc
   209701 ccgtctccag gttctgctcc acgatttcgc ggaagctcct gccgcgaagc gtattgggct
   209761 tgtggctcgg gaaaatttcg caatatttgc tgttggcgac caggatcctg tcatcggaat
   209821 cataaaggac gaagccatcc gaaatcacct cgagcgcggc cgcgatcgtc cgccgctgcc
   209881 gctccgcctc gtcttcgagc ttcttctttt cgatcgcgct ttcctggaaa agcgatagtg
   209941 tccttgccat cgccccaaat tcgtcaccgc cctcctgagg tatctcgacg tcgtagcgcc
   210001 cttccgtcag atcgccgatc actcgattga ggcgccgcag agggcccacg atcgagcgca
   210061 ggacgaggag cgtgagcagc gagccgatca gcaccacgcc gcccaccagg atggccgcgg
   210121 tcgtggccgt cttctcggtt tgaacgacga cctcgttgcg ggcggcctcc gcctctgcct
   210181 ttacctgttc gaccagcctg ttgaggtctg tgtccacctt gccgctgtgg gtgcgcgcct
   210241 ttgccagcag ggcattgccg acgatgcggt tatcctgcgt gtagctgtcg gctgcctgca
   210301 gcgccgtttc catataagcg tcgacctcgg cgccgatttg ccggacctcc acgggtgcat
   210361 gccttgcaag ccgttccagc tgcacctgta gtcgcgcgcg tgcctcgtcg gcgttgcgct
   210421 gggaattcat cagcaagctg acggacaggt cggtcagcca atatctgaga tcgccgaacg
   210481 ccacatgggc cgaggctgcc gacgccgccc tgtcgaagag ctctctcgtt tcggccatgc
   210541 gctcggcact gcgataaagt gcctgcgtga gaaaaaggga tgaaagaaca aggctgacca
   210601 gtccggccgc cgtaagcgcg gccacgcggg cagagatcgg cagatcgatg atccggctgt
   210661 cgagcctttt cgtgggccga acggcctctg tcgatcgcag cccgtgccct aacgcgctca
   210721 cttgaacaag acgatgctga tcgcaccgcc caggtcgccg gccttgccgc cttctttcgg
   210781 atagccggtg acgtcgattt cgccttttgg cgatccatga caggaaaggc atgattccgt
   210841 gtaatattcc ggcagcagca tccggaaagc gggccggccg ttcacctgcg tcacttctgt
   210901 gtagagttcg cccttcggcc gcttcggatc cgaaaatatc tcgttgatga ccctcgcttc
   210961 ccaggcatcg ggcagcgact tgcggttgcg cacgaggact tccggcgccg taacgcggac
   211021 cagcgcctca ttgccggcct tcacggcgaa tttctcgttc atcaggcggg caaaaatagc
   211081 aggaacgaac cccttgaacc ctatgccggg ccggttgatg tcgtcctgct cttcatccac
   211141 gacctcgcgc atcgcctcca cttgtgcctg caggagcttg cggtcgcggt cgccgagatc
   211201 atccgagatc agcggatggc cggtacgctc gccgtaaaag gcgatcgctt cggttgtgaa
   211261 ccgctcgccg ttaagcttct tgtctccgat tgccggatcg ttgatgagcg actggtaatt
   211321 ggaaagcacg ttccgggcag cgcgcaatag ttcggcaagc cgcgttccgg tggcgacatc
   211381 ggcggcctcc tcagccgcga tcgaaggtgc gaaaagcgcg caaccaaaca aagccgttac
   211441 gatgcagttt cgcgccaggg ctgtgagagc tcccatttgt ctttcccccc aggaggaagc
   211501 gcaagcaaag aggatatcac aggagggcct gcggaaggag tcacctggag aactgacttg
   211561 ggcgccttcc aatgacctcc gccaatgaaa cggtcctgcc ttcggcggcg ctgagatacg
   211621 acgcctccac caaagcgaag gtctccagat tatccaggcc ggacgtatcc ggctcgcgcc
   211681 cggcacgcaa ggcttccacc caatgctgct ggatgcgtga gacgctttcc tggatgttgt
   211741 gccaaggagg cgccgcccag gaaagaaccg gcggctccac attcgtgact ttcgtgccgt
   211801 ccttcgaatg catggtgagg tgatagccct gcgaaagccg cagggtgccc ttgcttccgt
   211861 caacctcgat cagggtttcc ggaaagggct cgatcggcaa cctggtcgca tagctgcagt
   211921 ccacgatgga ggtgatcgcc ccttcatgat ccaggagcat cgtcgcgaca tcctcgccgg
   211981 cgatcgccgg attgacccgc cgcgtgcgcg ccgtcaccgc tgtcgcatcg ccgaagatgt
   212041 agcgcgcgac atcgagtgca tggatcccaa ggtcctcgat aatgaaacgc ttgcccgttg
   212101 ctagataggg ctggccggaa aagacgtcat agcccgatcg aaagctcacc cgcccccaga
   212161 acacctcccc gaccgtgccg ctgtcgatcg ccgccttaac cgcccgtatc ggcgactgcc
   212221 atcggaagtt ctcatgtacc atgaatggga cccctgcctt cgcgcaggct tcgaccattg
   212281 cctcggcgtc ctccatggtt ggcgcgatcg gcttctggca gattgtcgcg atcccgtgtc
   212341 gtgcggccag ttccaccagc gaccggtggc ttcccacggt cgtggcaatg tcgacgaaat
   212401 cgaagccgcc atcggcaaag aggtcgtcta cggatagata gcggcgggtg atgccgaact
   212461 cgtcaccgac ggccctcagt ctctcgggat cgcgatcgca gatggagacg atccgcgccc
   212521 cttcggcgtc acgccagcca tgcatctggt tcacggcgaa gaagccgcag ccgatcagcg
   212581 cgcctttaag gtccgccatg ccatcacccc tttttcgcaa gctgcatcag cgtgacctgt
   212641 tgctgcagcc ggcgctgcgc ctgatccacc acgacggcca cgatgatcac gatccccttt
   212701 atgaccatct gccagaagga cgaaatgccc atcatgacga ggccgtcgga aagaatgcct
   212761 atgacgaagg ctccgatgat cgtgccgccg atcgtaccgc ggccgccgga catcgaggtg
   212821 ccgccgagaa ccgctgcggc gattgcattg agctcgaagg agttgcccgt cgcagggtgc
   212881 gaagccataa gctccgacga tatgaccagc ccaacgatcg cggcacagaa gccggagaac
   212941 atgtagacga acatcttcac cctgttgacc cggatgccgg acatgcgggc agcacgctcg
   213001 tttcctccga cggcgaagat gtgccggccg atcggcgtgt accgggcgag gtaggcggcg
   213061 gcgagcgcca caacgataag gatccagatc gaaaccggca ggccgagcag ccggccggag
   213121 ccgaggaagg caaagcccgt cgtcgagagc tcaggcttgc cgacgagatt ggggaaggtc
   213181 tggccgcccg acgagagcag cgcaaagccg cgcgcgacat agagcgtacc gagcgtggcg
   213241 atgaagggtg cgacgttgag ctttgtgatc agcaacccgt tgaccgcacc aatgacgata
   213301 ccgaccgcca gcgtgatgag gcagacctcg acaacgttga aatagatcgt atagccgaac
   213361 tgcagatcga tgccgttgag gatgagcccg cccgcgacca tgccgcatag cccgacgatc
   213421 gaaccgacgg aaagatcgat gccgccggtg atgatgacga aggtcatgcc catggcgagg
   213481 aaggcgttga gcgccacatg tttcgacatg aggatgagat tggcggttga aagaaagttc
   213541 ggcgcgaaaa tcgaaaagaa ggcgatcacc gcgaagaggg cgatgaacgt cctgagcttc
   213601 atcaaagtga gcagcaccga gccgctcgcg gcgtccgttg cggtggtcgt cgtcgttgcc
   213661 gtcgtcatca ggcgtgttcc cttgtcgttt tatgcccttc ggccgaagcc ttcacgatca
   213721 tctcttccgt cgcatcggcc cggccgacga ccgtgaccag ccgtccgttg ctcatgacgg
   213781 cgatgcggtc ggagagcgcc atgacctctt cgaggtccga ggtggaaaag aggattgcga
   213841 gcccttcgcc ggcaagccgc cgcatggtgc ggaagacatc cgctttggcg ccgacatcga
   213901 tgccacggct gggttcgtcc atcagcagca ccttcggctt cgtcatcaac gccttgccga
   213961 taacgacctt ctgctggttg ccgcctgaca tcgaggttac ctcgaagtcc gggttcggcg
   214021 ctttgatgga aagatcgcgg atggccgcct cgatcgaggc ctgctcccgt gcgccgacga
   214081 tatggaagcc gaagcggacg aagcgatcca ggctcgcaag cgtcagattg ctggcgatcg
   214141 atagggcctg aaccaggccc tcgcgctggc gatcttccgg gatcagcgcc aaacccgcgc
   214201 ttatccggcc ggcggtgtcg gtggcgtcga tttcaatccc gtcgacaaaa acccggcccg
   214261 aagaatgcgg gtgctggccc atgacgcatt cgaagaactc gctgcgaccc gcccccatca
   214321 atccgtagat gcccagcacc tcgccggcgc gcagcgagat cgagacatga tcgaccgcga
   214381 gcccgccggt tcggcgcggc aggcagatat cctcggcgcg gaaggcctcc tcgccaaggc
   214441 ggtgcgctat cgatttggcg aaatcctttg cgtccgagcc gatcatcgac cggacgatcc
   214501 acttggtatc gatgtccttc accatcgcgt ggccagtgat ctgcccgtcc ctcagaaccg
   214561 tgatgtagtc gccgatccgc atcagctctt cgagccggtg agaaatgtag acgatcgcca
   214621 ccccttgagc cttcaactcc ctgatgacct tgaaaagaac gtcgacctcc gccgccgaaa
   214681 gggccgatgt cggctcgtcc agaataagga tgcgcgtgtc gagcgagatc gcctttgcga
   214741 tctccaccag ctgctgctgg ccgatcggca ggtcttcgac gagcgtctcg gcatcgatcc
   214801 cggcatcaag cctgtcgaga aacccggtcg ccctctcgac ctgcgcgcgg tgatctatgc
   214861 cgcgaaagcc ccgggtcagc tcccgggtcg cgaagatgtt ctcggcaacc gagagattgc
   214921 cgaaaagatt gagctcctgg aagaccatgc cgataccatg gcgctgggcg tcggccggcg
   214981 agtgaaattc cacctccttg ccgtcgagca ggatgcggcc gagtgacggc ttctcgacgc
   215041 ccgcgatgat ccgcatcagc gtggacttgc cggcaccatt ttcgccgacg agcacgttga
   215101 cggcgccgcg ccggagagaa agatccgcat ggcgtacagc aacgatgccc gagtagacct
   215161 tcgtcacgtc ttcgaggcgc aggatgcaat catcgtcgtc acgggcttgc atgatcatcc
   215221 acccaccgtc aatcgagccg gaacgaacat cggcagctgg cccttggccg gcaagggata
   215281 ggccccgaca gcgtcgagct tcttgccgac aagtccgtcg cggggaagct tttcaagcac
   215341 cagcccgttg acatgcgtgt tgaaggcctt gccgaattgc gcccactcga tctggttctt
   215401 gaattcgttg aaattgacga agtcgaggct gtcgcggatg gccgtgcccc ttatcgccgg
   215461 acctatctgc acgcgtgcat ccgccttgcc gtcggcatcc gcatcgacct cgacataggc
   215521 cgaacgcgat ttcgtctcgg ctttgacgat cgtgccggaa agacgcgccg cgaaggtcca
   215581 gggagcactc ccctgctttt ccttatggcc gtatttcgcg ccggccgcct gcggatcgct
   215641 cccggcaagt gcggcaacct cggtgaatgg accggctttc cggtcgagat aggaaagcac
   215701 cttcgtgtcc cagatctcgg cgaccatgcg gttgggattg aagccgccgg aggcggcttc
   215761 cgcagcctct tcggcggtcg gcgtcttgat gatcttgcag cccgagagtg ccatcacgcc
   215821 cgcaaccgca agcgcggccg cgactttgaa gttcggcatc gaaattcact ccatcacagg
   215881 acaggcacgc agcttggttc tgccgcgtgc ctgagcgggc ggcgcggacg gttcttcgcc
   215941 cgctcccgct ccaactcttt gaaaccgatc agtcgatcag cgcaaaggtc tcgagctggc
   216001 cggcgttttc gctgttgatc agcacgcagt ccatgagctg cttttcctca gccggggtct
   216061 tgccggtggt gatgtattcg tgcgcctgct gcactgccat ctgcgcctgg gcgtaagcgg
   216121 gctgcagcac ggttgccttg atcccgccgg acttgatcga atcgcgaacg tcgttcgaac
   216181 cgtcgaaacc gacgacgatg acgtccttgc ggccggcagc atgcaatgcg gcgatcgcgc
   216241 ccatggccat ggtgtcgttg ccggagatca cgcctttgat gtcggggttg gcctgaagga
   216301 tcgtctccat tttgctgtag ccctcggtct ggctccagtt cgccgattgc tgcgcaacca
   216361 tcttcatttc cggatattcg tcgataacgt cgtggtagcc cttcgagcgg atgccggcat
   216421 tgagatcggc ctcgcggccc aggagctcga cataattgcc ggattcgccc attagcttca
   216481 cgaattcctc ggcaccaagc tgcgcgccct gataattgtt ggacacgatc tgcgagacgg
   216541 caacgccggt cgcgttgatc tcacggtcga tcaggaagga cgggacgccg gcgtctttcg
   216601 ccttctggac tgcagcaatg gatgcctccg aaccggcatt gtcgagaatg atcgccttcg
   216661 cgccgcggcc gatggcggtg tcgattagct gcgattgctt attggcgtcg tcgtcatgca
   216721 ccagcaccag cgtttcgtag ccgagctcct tcgccttggc ttcggcaccc accgcttcgg
   216781 ccttgaagaa gggattgtcg tgcgacggcg tgatgatcgc gataagatcg gccgcatagg
   216841 ccggaatggc ggagctcgcc gccaatacag ccgcaaaagc ggcaatggtc attctgcgtg
   216901 tcagtttcat ctgcatttcc tcccaggttg aaaaatgccg gagccagcct cacaggctcc
   216961 gttttccgtt cgcgcaatca ggtgatgcgc cggatgctgt cggcgatctc ctgcggctcg
   217021 aagacgcgtt tccagtcctc gcgcatgagc atcggcttgc cgaattcgat ggccttgttg
   217081 caggcgtcgg agaagacgcc gggcgtctcc tcgaagatca ccgcgccaag cacgttcatg
   217141 tggccgagca gaaagtcgcg cgctgcctct ttcggcacgc cgcgcctgac gcattcctcc
   217201 atggcctcgc gcatgacgac cagcagcgag gcgcagaccg tttcggaaag cccgggctcg
   217261 agcagcgcga tctgctccac cgtcacccgg tgcgagcgca taaccggcgc ccagatgatc
   217321 ttggcgatct cctcgccgag cgcataggcc tcttccggcc cctgcatcag cgccgagacg
   217381 atgtgctgcc tggcggcgac gccaccgaag aaatcgcgct tggccgcagg atccgtctcg
   217441 tcgttgaaaa tcggtggatg gcagggatgg gtgacgaaat aggtaagatc gctacgctcc
   217501 ggcagatgac cggcataggg cgccgccgcg tcgaggacga tgaccatcgt gccgggcttc
   217561 agccgatctg caatcgcgga agcgaccttg ccgatcgccg tatccggcac ggccagaacg
   217621 accacctcgg cgccatccag agccgcatcg gcgtcaaccg tcgaaagccc aagctccgcc
   217681 agccgcacct tgcccgcttc gctcacttcg acatggcgca cgtcgaaacg cgagcctttg
   217741 aggttcttgg ccaggcggca gcccatcttc ccgccggcgc cgaacagggc aatcgatgtc
   217801 atttgcatct cctcaactat cttgctcatc cgcatagccg agctggtata atgagtcaat
   217861 gagcatatca ctcagttttg cggtcatgct caaatagatt gacaactcac gactatcgga
   217921 ttacgactga cgaaattcaa aattcgtcac tcatcatcag gagacaggat gagcgatcta
   217981 accgacagca tcgatgcaac cagacaggaa aacgtcacgc ggattctcga cgccgccgag
   218041 cgactgttcc gccattacgg ctatgccaaa acaaacgtcg ctgacatcgc gcgcgagctc
   218101 gatatgtcgc cggcgaacat ctaccgcttc ttcgcgtcga aaacggaaat ccatcaggcg
   218161 ctctgctcgc gcatgctcgg tgcaagctat cagcaggccc atgacatcgc gtacctgcct
   218221 ctcagcgctt cagagcggct gaggcgttat gcgcagggtc agcacaagct caccgtcgaa
   218281 acgatgctcg acgaaaagaa agtgcatgag atggtcgtcg tcgcgatcga acacaactgg
   218341 cacgtcatcg aaaagcatat cagccgtctc gacgacctcc tcgcaggcat tattcgcgaa
   218401 gggatcgaag ccggagagtt cgtggatacg gacccagcgg tggcagccag atgcttcggc
   218461 gccagcctcg tgaccctctg tcatccgcag atcgtcgccc agtgtcttgc caaggaaaac
   218521 cgcgccactc cggaggagct gatcgagttc gccatccggg cgctgaggaa atagcgcaag
   218581 tcacccagac atgcggagcg gttttggcgc gacttcatgc acagaaagaa cgtccagccg
   218641 ccgcagagcg gccaaagaga gtaagagcga tgtcttcacg aagtgccctc aaccgaccgt
   218701 ctgtctccag tctcctgagc ctaatcctgc ttggcgccgt tctctccggc tgcacggaag
   218761 aaaaggccga gacgaaggaa gtgatacggc cggtcaaggt cgtggagata gccgcggcgg
   218821 gtaagccaag ggagctccac tattccggct ctgtaagagc gcgcacggaa atgaatctgg
   218881 gcttccgtgt gggcggcaag atcaccgagc gcctcgtcaa tatcggcgat agggttgaac
   218941 caggtgatgt tctcgtccgc gtcgacgcca ccgactatca gcttgcggtg cggagcgccg
   219001 aggcaagtct gctcgcggcc gaaaagcagg tgcagacgac ggggcttgcg aagctcagag
   219061 ccgaacagct tttcaacaaa tccttctcct cacaggccca gctcgatcag gcaaccctac
   219121 tttacgatca ggcggtctca acgcgcgacg ccgcggcatc gtcgctcagc caggcgaaga
   219181 accaggtaaa ctatacggac ctcaaggccg accagaacgg catcgtcacg gacgtaaacg
   219241 ccgatatagg ccaggtcgtc ggcaccggaa cgcccgtcgt gactgtcgca gtcgacgggg
   219301 agaaggaagt cgaagtcgcg gtgcccgaaa tcgacatcgc cgaattcagg ccgggcaaac
   219361 cggtgcaggc gcgtttctgg tcggacgaca tgctcgtgct cgacggccat gtgcgcgaag
   219421 tttccggcag cgccgacccg cgctcacgca ccttttcggt gcgcgtcggc ctgccgaaag
   219481 acgagcgcgt gctcctcggc atgacggcga cggtcgaggc gactgcagga agctcggcgc
   219541 cgctcttttc catcccgctg agtgcgctgt cgaagaagga tggccagaat atcgtctgga
   219601 tcgttgatcg tgacttctcg accgtccatg cacgcccggt caagcttgcc gacttcgccg
   219661 ataacggcgt gcgcgtcgtc gagggcctcg gcgccggcga cctcgttgtt gccgcgggca
   219721 cacaattcat ggccgaggat ctgaaagtga ggctgcaggc ggacgaacag caatcggccg
   219781 agcaacagtc cgcccgggcc gaaacgcccg aactcctccg ctaacctcca ccgatagaac
   219841 gggactacgg ccatgcaagc ctccacagag gacaggaaac cgttcaatct ttcgcgctgg
   219901 gcgatcgggc atccgagcat cgcgcgcttc ctcctggcgc tgatcatcat cacaggcgcc
   219961 ctcgggctcc tgcgcatggg acaacgcgag gatccggaat tcacgttccg cgtcatggtg
   220021 gtgcaagccg tatggccagg agcatccatc caggaaatgg aagaccaggt cgtcaacaag
   220081 atagagcgca agctgcagga aacgccgcac ctcgatttcg tccgctccta tacgcgcgcc
   220141 ggcagcgcca tcatcaccgt ccagatcgag ggcgacacca acgcagacga ggtcgccgac
   220201 gcgttctatc aggtgcgcaa gaaggtgggc gacatagcca acgagctgcc cgaaggcgtg
   220261 ctcggcccct atttcaacga cgaattcggt gacaccttca tcaccttgca ttcgatcagc
   220321 ggcgacggct tcagctatcc ggagctgagg cgcttcgcga tcgaaggccg tgacatgctg
   220381 ctgacgacgc caggtgtcga gaaggtggtg atcctcggcg accagccgga gaagattttc
   220441 atcgacgtct cctccaaggc gctcgccgaa cgcggcctga cgctcaacga cctgcgcgat
   220501 gccattgccg gccagaacaa tgtcgatcac gcgggttcca tcgatacggg cacgcgctcg
   220561 gttcgcatct cggttgaagg cggcgtcacc aaggccgaag acatccgtga gcttcggcta
   220621 agggcgggag aaaggaccat tcggctcggc gacatcgcga cggttacttc cggtctggaa
   220681 gacccctatt cccggaaatt ccgtttcaac ggccacgaca gcgtccagat cggcgtcgtc
   220741 atggcgaagg gtttcaacgt cacggacgtc ggcaaggcgg tcgaggctac ctacgatcga
   220801 ttcgagtccg cccttcccta tggcgtgtcg gtcgatcagg tctccaatca gccggaggtc
   220861 gtcaccgaag caataagcga attcagccac gcgcttgtcg aagcgctgat catcgtcctc
   220921 gtcgtctcct tcctgtcgat cggctggcgc tccggtctcg tgatcgcgat cgccattccg
   220981 ctcgtgctcg cagccacttt tgcgatcatg tacgaactcg gcatcgacct gcagcgcatc
   221041 tcgctcggag ctctgatcat cgctctcggc ctgctcgtcg acgacgccat gattgtggtc
   221101 gagatgatgg agcgaaaact cgaagaaggg ctggaaaaga tcgatgcggc gagcttcgcc
   221161 tattcctcga ccgcttttcc catgctgacc ggcaccctga tcaccaccgc cggctttatc
   221221 cccgtcggct tcgcgcaatc gaccgccggc gaatatgtcc gttcgctctt ctatgtcgtc
   221281 ggtattgccc ttgtggtctc ctggtttgtg gccgtctact tcactccttg gctcggctac
   221341 atgatcctga agcagcgcca ccacgccggc acccatcacg acgtcttcga tacgcgcttc
   221401 tatcgtcgcc tgaggtcaac cgtcggctgg gcagtgcgcc accgcatcac tgttctcctg
   221461 atgacgctcg ccattttcat gacgagcctc tgggggttcc agttcattcc gaagaacttc
   221521 ttcccgcaat cctcgcgacc cgaaatcctg gtcgacctct ggctgccaga aggaacgagc
   221581 atcaaggaag tggaaaagca ggcaaaggcg ctcgagcaac gattgatgga cgataaggac
   221641 aagcgcttca tcgccaccta tatcggagaa ggcgcgccgc gcttcttcct gcccctcgac
   221701 cagcagcttc gcaacccgaa cttcgcgcag ctcctcgtca tggcgaagga cgaaccagcc
   221761 cgcgagaggc tgatcggcaa gttgcgaacg gtgcttgccg aggaattccc ttcgatccgt
   221821 accaaagtcg accgattgtt cctgggaccg ccgaccggct ggccggtgca gatgcgggtg
   221881 atggggcccg accgcgaaga agtgcgccgc atcgccaacg aagtgaaggc gaaatttcgg
   221941 gaaaatccat tgctcggcgc cattcatgat gactggctgg agcctgtgcc ggcgatgaag
   222001 cttgtgatcg accaggaccg cgcccgtgcc ctcggcatca cctcgcaacg tatccgccag
   222061 atgctgcagg cggcaatgtc cggcgttccg ctggacagct tccgggacgg agaagaggcg
   222121 gtctcgatcg tggcgcgaga gcccggcggc aatcgccatc tgctctccgc ggtccagtcg
   222181 gtgtatgtgc ccaccgactt cggtggcttc gtccccgtat cgcaggtcgc caaggtcgtg
   222241 cccgtgatgg aacagggggt cgagtggcgg cgcgaccggc tccccacaat caccgtgcgc
   222301 gcaacgctcc ccgacggcgt gcagtcgaac gacgtcgcga tgaagctctt cgacgaactc
   222361 aggggactga gagacagtct cccgccggcc tacaaggtgg agatccaggg tggcgccgag
   222421 gacagtgccg aaagccaggc ctcgatcgcg gccaaggcgc cgatcatgct ggtggtcatc
   222481 gtcatccttc tgatggtgca gctccagcac ttcggcaagg cgatgctggt gctcgcgacc
   222541 ggtccgctcg ggatcatcgg cgccgcagct gcgctgctca tcagcggagc gcccttcggc
   222601 ttcgtcgcca tcctcggcgt tatcgcgctg ctcggcatca tcatccgcaa ctcgatcatt
   222661 ctcgtggacc agatcgacca ggatatcgcg gccgggatgg agcgttacga ggcgatcatc
   222721 ggtgcggcgg tgcgccgctt ccggcctatc acgctcaccg cgctcaccgc ggtgctggca
   222781 ttgatcccga tctctcgcgg cgtgttctgg ggaccgctcg cctatgcgat gatgggcggt
   222841 atcctggtgg caaccgtttt gacgatcgtc gtgctgccgg ccgcctatgc gctcttcttc
   222901 ggaaaggaac cgaaagcgcg caagacggcc ccggggccgg cggccgcgca aggagatgcc
   222961 gacgaagact ccacgcccta tccggcgccg ctggcggcgg aatgacttct gccggggcgt
   223021 ggcacgccga ggtcttgcct atttctgtcg gaatcaaaaa aatgtgataa tgtaatttca
   223081 gattcaatct gcgatcatag gtgaaggcca aagcaaggag cgaggagcag ggaatgagca
   223141 ccatcatgtt cccgcagcgg aatctgcgcg aagaaacggc gccgctccgc gcgcagattc
   223201 tcgacagatt gtcgaagttg ccctgggacg gactttcttt cgagcacccc atcccgggtc
   223261 tctcgctcta tcgcatcatc cagcccgccg gtcccttttc gagcgtttac gagccaagcc
   223321 tctccttcat catcaaggga agcaagaatg tccgcgtcgg caacgagacg atggtctacg
   223381 atgaaggctg tttcttcctg acggctatcg gcctgcccgt gaccgggcag atctgcgcgg
   223441 cgagcgaaag ggagccctat gtcgcagcgg cgctacgcct ggacatggag aaagtccggc
   223501 gcatcatagc cgatcacgac atacatccga ccgaccttcc cgagcgcgac ctgggcgtgg
   223561 ctgtaggcac tgcgacttgc gagcttttcg atgcgctgtt ccggctgatc tcgcttgccg
   223621 gcgcgcccgc agacatacct ttcctggctg gccacatcca gaacgagatc atctaccggc
   223681 tcctcaccgg cgaacaggga gcgaggcttc gtcgcttcgc gcttgcgggc acgaacagca
   223741 atcgcgtggc caaggcggtc gcatggctga aggaaaacta caccaaacag ctgcgcgtgg
   223801 aagaactcgc cgaaatcgcc aatatgggcg tctccacgct gcatcatcac ttccgcgcaa
   223861 tgactgcaat gagcccgctg cagtttcaaa agcacctcag actgcatcat gcccgggaac
   223921 tgatgctttc ccagtcgctc gatgcggcga cggcggcact gcgcgtcggc tacgagagcc
   223981 cgacccagtt caaccgcgag taccgccgcg ccttcggcca tccgccgctg cgcgacataa
   224041 gggcgatcct gaattctaac gattcgacca ggcggagccc tgcaggttag agcaattcca
   224101 ccgcccacga cgccgacgtc ctgatcacga tcccgttaac ctggcaggaa tgggcaataa
   224161 ttcggcagga tcgaatctat cagcctgcga gatggtcttc taagctccgg atctcgctca
   224221 tgatcttagg ccatcatcct gaattatgaa cgtgatctat cccaaagttc gagcggggtg
   224281 cgggcgaaaa ccgcagtcat cttctcatcc cgctccagcg gcagtccggc gaatgttcgc
   224341 ggcattccgc attaacgcgc cgcaacgcga ggaaaaacac catggtgaat atcaagatca
   224401 acggcgtcga acacgcgatc gaagcagagg cggacatgcc gctcctgtgg gcgatccgcg
   224461 acctcgtcgg tttaacgggc acgaagttcg gctgcggcat ggcgcaatgc ggcgcctgca
   224521 ctgtctatgt cgacggctcg ccgacgcggt cctgtcaaac cttcatcggc gacatcgacg
   224581 gagctgaagt gacgacgatc gagggcctga aggggaaggt cgccgaaacg gtgcaatccg
   224641 tttgggccga actggacgtg ccccaatgtg gctactgtca gtccggccag atcatgtccg
   224701 caacggacct tttggccagc aatccgaagc cgaccgacac ggacatcgat gccgctatgt
   224761 ccggcaatct ctgtcggtgc gccacctatc accgtatccg cgcgggtatt cacgaagccg
   224821 cgaagcgtct ggaggcctga tatgataccg aaactaatgc aatcgatggc ccttcccgct
   224881 cgcgtcgaag cctcgcgccg ccaattcctg ctcggtgcgc ttgccgccgg caccggcatc
   224941 gccgttgggt accggctcct atccgcttcg ccggcccttg cgggcgaagc gcaagcgggg
   225001 aatgattcac atgcgttttc cccatatctg acgatcggcg gggatgggaa ggtcaccatt
   225061 ctctcgtcgc agttcgagat gggccagggc tcatataacg gcattgccac gctggtggcg
   225121 gaggagttgg acgccgactg gtccacgatc gacgtcaagg gagccgccgg caacatcccg
   225181 gcctacggca atatcgcctt tggaggtacc atgcagggta ccgggggctc gacatccatg
   225241 tcgacctcat gggagcgcta ccgcaaggct ggtgccgccg cccgagccat gctcattgcc
   225301 gctgctgcag cggaatggaa ggtggacgcc gcggagatca ccgtcgagaa cggcgttctt
   225361 tcccatccgt cgggcaagag cggtggtttc ggcgcgtacg ccgccaaggc gacgacgatg
   225421 ccggtgccgg ccgacgtgaa gctcaaggaa ccgagcgcct ggaaatttat cggcaatgcc
   225481 gaactgaagc gcttcgacag tgcccgcaag gcaaacggga ccgagcaata caccatcgat
   225541 gtcaagctgc cgggaatgct gacggcagtg atgattcacc cgcccctctt cggcgccaaa
   225601 gccaagtcct tcgatgcttc ggccgcccgc gccatcaagg gcgtggtgga cgtggtggaa
   225661 acgccacgcg gcattgcggt ggtcggcgag catatgtggg cggcaatcaa gggccgtgaa
   225721 gcggtaaccg tcgaatggga cgagtccggc gccgaaaagc gggggacggc ggagctgatg
   225781 tccacctacc gcgacctcgc gggcaagacg ccggcggcct tcgcgcgcaa ggacggcgac
   225841 gccgaggctg ccttcgcagc agccgccaag gtcatcgagg cgaccttcga gttcccctat
   225901 ctggcccatg ccgctcttga gcccctgaat gcggttgcac gcaggaacga ggacggcacg
   225961 atcgagatct ggggcggaca ccagctcccc gacgtgtacc agaagctcgc cagcgagatt
   226021 gccggagtgc cggtcgaaaa tgtccgactg aacgtcatga agaccggcgg cagcttcggg
   226081 cggcgtgccg tgttcgacgg cgacgtcgtg gtggaagccg tacatgtggc caaggccctc
   226141 ggcttccgtg caccggtcaa ggtgcaatgg acgcgggagg aagacacgcg cgccggccgc
   226201 tatcggcccg cctatgtaca tcgcctgaaa gccgggatcg atgcagacgg caaactcgtc
   226261 gcctggagcg atcacatcgt cggccagtca atcgtggcga aaacggcttg ggatggcatg
   226321 gttcagaacg gcgtcgaccc gacgtctgtg gagggggcga acaatctgcc atatgccatt
   226381 cagaaccaga cggtcgggct cacgaccacc gatgttcgcg ttccggttct ctggtggcgc
   226441 tccgtcggct cgacacacac cgccttcgcg gccgaagcct ttctggacga agttgcccag
   226501 gctgcgggac gtgacccact ggagtttcgc ctttcgatgc tggagccgca gtcgcgccac
   226561 gcaaccgttc tcaagctggc ggcggaaaag gcggaatggc agaaaccgct gcctgaaggg
   226621 cgcttccgcg gcgttgcggt cgccgagagc ttcggttcgg tcgtggcaca gatcgccgag
   226681 gtttccacag atgggaacgg cattaaggtc gagcgcgttg tcgctgcggt cgattgcggt
   226741 ctcgcgatca atccggatca ggtgcgcgct caggtcgaag gcggaatagg ctttggcctc
   226801 agcgccatcc tgggcgagga gatcacgctg acggatggca aggtcgacca gggcaatttc
   226861 gacatgtaca cgccgctcag gatcgatgcg atgccgaagg tcgaggttca tatcgtcgcc
   226921 tcgtccaatc ctccttcggg gatcggcgag cccggcgttc cgccgatcgg ccccgcagtt
   226981 gccaatgccg ccttcaaagc tctcggcaaa cggatacgtg tcatgccgtt cgcgaagtcg
   227041 cttaacgcct gagcgcccat cctccccatc gcatacgccc ggaactcgac ctcgagttcc
   227101 gggtggttcc ttggggatgc gacaaggaga ggcttcttta tgtacgtcca cttggacgca
   227161 cagatgcggt gctgcgttcc gaatcagcgt attcaaagct cccgcttgag aatttatcga
   227221 aatcgtccgt tttctcggaa ccttccgagg ggctgggtgt taggcgccgt cgctttgacc
   227281 aaggcgacgt gcacacaaga acgggtcggc tcttgtccct ccgctaagcc ggggtcgacc
   227341 cgggcggcgt cctcccgcct cccccctccc ggggcgccgt cggtcgctgc ggaacgtgcc
   227401 tcctccgcag cacgccggcg tgagaacgat cattcgagcg gcgagattga gcgcttccgg
   227461 atgtgaaccc gccacgcagg ttttcctgaa gcgcgggaga gcgggttgag gaaaactgtg
   227521 tgcggtttcc cgcccgctcc cgctccatct ctggaagcga tgacgtccat gtttccaggc
   227581 cgacccgacc tgaaaacatc gtgatctagc cgaagaacag tgaagcgatc atgatcgccg
   227641 aaaccagtcc gacggcagcg atgaacacga tcaggtcgac cgtggggtga tggtgcaaac
   227701 cgcgtcgcat ggcgaactcc tccacccgtt gcgggtcaag cagaacgccc atgcgccgga
   227761 tttgttcatc cgtgatcatt catgcagtgg cagccgagcc gattcgccca atcagtgccc
   227821 gcctttgcgc ctcgcatcgt gactgtggtg gcgatcaggc tcgcctccgc cgccggaaac
   227881 cttgctgcgc gtgcgccgct cggaatcggc cggcggcttt ggtatctcca gcggagcctt
   227941 cgcgttttcg tgcgaggctc cgggaccgcc ctgacggatg cttgccggtg tcttcttgga
   228001 agtggacatg cgctctgcct catctgtcct gttgataacc ctgatgggtc gtattgacct
   228061 tggtgttgcc ttgctggcct ttcttctcgg ggttctctgc cgtatccggc ttcttcgcgt
   228121 cggtggatac ggttccgggt tctcccgttc ccttgtcgct gcgattttcc gcaggaatcg
   228181 gcggcggacg gctactcatt gaaacctcct cactcacata tcgttttaga gccgatgtct
   228241 tgtttgacct aaccgatcag gccgcgcgat gttcctggcc gcgtggcgat cgccgccgag
   228301 tgcaaggtgg cgccaaacgc caatcctaag cccatggcga tataggtcat cgccaggtcg
   228361 gatttcggca gagcgagttc ccagccaggc gtgaggcgtt tcggcaccag accgtaatcg
   228421 acgacggctg ccagcacggt ggtgcctgcc gcagcggcaa tcgcccgagg tggcgagggt
   228481 ctggcatttc gtcccagcat ggccgcgaag gggagagccc accagaacga ggcaagcata
   228541 tgggtcgcaa agccggtgcc ggtgtgggca aggtcgagcc gcgataccga gccggcacga
   228601 cggccgtata tccaatggct cgtcgcgttg atcggccgcc agggacttct gttccggcgc
   228661 tcggccgaga ccgtcagcac cgctaccgcg gcaaggccag cgcatatccc gcttatagct
   228721 atgagtgacc cgcgtggcat tgatctctcc cttggcggcg accggccgac ggatgaaccg
   228781 gcggccagcc tgtttgttcc gacttcctga agatcgtcgc tggcgcgact actcggcggg
   228841 aagcggaacc gctgccggca tcgctttgct gccggcaagg ctgcgctgac ccgccgccac
   228901 cgtgacgacg gtcgccgccc cggccgccac ggatacccag aaacccttct gcgcgccgta
   228961 attgtcgaca acccagcctg acacgaatgc gccgagcgcc atgcctatac caattcccgt
   229021 catgacccag gtgacgcctt ccgtcagcat cgattccggt acacggcgct caatcaaacc
   229081 gaaagctgtg atgaaggtcg gtgagatggc tatgccgctg acaaagacag caaatgcaag
   229141 gaacggaacc gtatcggcca cgaggagagg gagggacgtg atggcgatta cactgacggc
   229201 gatcagaagc tgcctctgca gcggcatggt cgggttcagc gcgccaagtg ccagccccac
   229261 caggaacgag ccgacggcgt agacgccgat gaccaggctg gctgcctgcg gctgcccgag
   229321 ctctttcgtg atcgccacga cactgacctc cgctgtcgcg aagatcgagc cgacgaagat
   229381 aagcgcaagg gtgatgatct gtaccggtct ttgacggatc gccgacgctt gcgaggcgct
   229441 ggcctcgatg ggatgcacct tcggctcggt cgaacgctgc agaatgaatg cggccgtccc
   229501 aagggcgaga aagatagtgc ttgtcagcat gccggcttcg gggaacagcg caaccgccag
   229561 gccaaccgac agcgaagccc cggaaatgta gacaagctcg tctgccgaag actcgaatgc
   229621 gaaggcggtg ttcagctcgg gccgattgcg gaatatttcc gtccagcggg cgcgaacgag
   229681 cgcgggcatg ctcggcatcg cggcggcgag gaaagccaaa acgaacagcg tccacgccgc
   229741 ccagtcgcgg ttggccgcaa tgatcagcgc caggaaggct gcgaccgaga cgatcgtcgt
   229801 cggaacgaca acggccgtct ggccgacgcg gtcgaccaga cgcgatatct gcggggcgac
   229861 gagcgcgttg gtgagggcga aggtcgcgga gaccgcgccc gccagccagt attcgccgtg
   229921 ggtctgagac accattgcga cgatgccgat cggggccatc gctatcggaa gtcgcgcgaa
   229981 gaagccggct gccgagaagc ccttggcccc cggcgcccta aatatttctc cgtaaggatt
   230041 ggacataaga cgctccttaa aaagggatgc tgatgacata cgcggcgtat gtcatctagt
   230101 tagttgcata cgtcgcgtat gtcaaataaa atacggagcg tatgtgaata ggagacgtga
   230161 tgaacaagca gcgcaaggag atgatcgcag agacccgcgc gaaactgatc gcagccgccc
   230221 ggcatgcctt cggcactgtc ggctatgcgg actcgtctat ggacgatttc accggtgaag
   230281 ccgggttgac ccgcggggcc ctgtaccatc acttcggtga caaaaagggt ctgctgcagg
   230341 ccgtcataag ggagatcgac gccgagatga cggcgcgcct gaacaaggtc tcatcagagg
   230401 cgccgacgcg ctggcaaggc ttcgtcgacg agtgcgttgc ctacatccgc atggctctcg
   230461 agccgcagat ccagcgcatc atgttccgtg acggccccgc cgtgctcggg gacatatccc
   230521 aatggcccat gacccagggc tgcatcaccg cgctggccgg gagcctcgat cggctcaagg
   230581 ccgaaggcgt ggtcatcgac atcgacaccg aagccgcagc ccgcctgatc aatggcgcaa
   230641 gcagccaagc agccctgtgg atcgccaatt ccgacgaccc gcaggagaca tcccaaaaag
   230701 ccgtggatgg gtttcaggcc ctgctggagg gcctgagggt gaaaagggac tgacgcggct
   230761 acgcccgata cagcagaatc gggcggaccg gcttcctgtg acacgcacag gaaagtcagc
   230821 ctgaacggtt tcgtataatc tagaaccgca cgaccagacc gaggatcggc ccctgctcga
   230881 cgacgtcgaa gacgaatccg tcattgctgt agtcgacacc gagcgcacga taaccggcaa
   230941 gcgccgaaat cgtatcgctg aagcggtagc cgatcgctgc ggcgacatcc cagtcgagat
   231001 cggctccgcc ggcaccgacc agcccccaac ccgtcagata gacttcgggc gtaaacgaat
   231061 atgtcccgcg aaagcctgca atgccatcca cccaggtcgc atcatcggat ctcgaaacac
   231121 cgccgggggg gagaatgccg ccgctgaagg acaattcgct ttcgacggac cagacacgca
   231181 ggcctcccac gatatcgagc cgcgcggcac tgtcctcata aattgcataa ccggcgccga
   231241 gcgtgccggt gaatgtctcc gtggagagct tgacatcgtc tgcgataatt cccctgggcg
   231301 taccgccttc gccggaaagc ttgatataga tcgcgtcgcc gaaaatgctg tatggcccgt
   231361 tgcgtgcctc tgcggtggcc atcaaggcaa aatccagatg atcgaagaca tcgctgaaac
   231421 tcgcatcaac atcgacagcg ggcagaccga actgctcgat atcccctgac agccctgccg
   231481 cccagaagta cggagagaag gaaaacgtcc agccgctctc cgtcgtgacc tgctgggttt
   231541 ccggagccac cggagaatag atgtctgccg ccgtggcacc gccggcaagc aggcaggttc
   231601 cggccaaagc caaggttcgt atgaaaccag acgtcatcac atatctccca gaaaatgccc
   231661 gccgtcgcga tcggccgggg cacgacaaaa tcaatattgc gtattcccgg atgacagtcc
   231721 gcggggcttc tccggaacgg ttcgaactca acgggccgtg tttcccgcat tctcgctgct
   231781 cgtcagcgtc tcctccagat tgaccttctt gcgcggcgtt ccacgctgct cgatgatggt
   231841 gaccggcgcg gtgatcgtgg ccgccgcaac ggtaccgaca ttcttggccg tgcctgcgac
   231901 gacggcagtg atgccttcgc cgagcgagat gtcggaatcg gtcagcgtct gccctttgat
   231961 gatccgctgc ccgatcagtt gcacgatctc cgggctttcg gcgaattttc catgatgcag
   232021 gccgtcatcc gtctggacct tggtgagatc gatcgccgtg atgccggcag tctccaactg
   232081 tgtacggtag ggctcggcgg tcggatcgat cgcgccgagt cgagacacgt cgccggagat
   232141 cagccgcgat accgcgagcg cccggtcgtc ctgtgagacg aagatcgtaa acttcgggcg
   232201 tgccttgccc atatcgaccc attgcttggc gaagacgtcg agatcgatgt cgggcgaagc
   232261 gagaatcacg ttctcgatct ttggcgcgat gccgccgtcg cggatcccca tctggcgcag
   232321 cgactccatc gtcagccagg ttcccataga atgggcaagg atggtgatgt ccttgacgcg
   232381 cggcgcggac gccagcgtgc gcagcgtatc ctcgagtgca gtgcgcgagt aattggtgct
   232441 ctccttgtcg taattatagt cgaacagccg tgcccgcgat ggccaggtga acaggatcgg
   232501 ggtcgcctgg gcgcccgaat cgtgaacaat ctgcgccagc cggaaaacag catcctcata
   232561 gcggttgttg aaaccatgca cgaagagcaa cacgtggccg ccctcattgt gaacctggaa
   232621 ccagtcgcgc gcttcgtcat tcgatgccag cttgcgcacc cgcgtgacag cgaagtcggt
   232681 ttccggattc ggaggaagct tccgcggcca ctgcaccgta ccgggcttgc ggcgcgagtc
   232741 cggcggaatc gaaaccgcaa catcggtcat agacagtgtc gggctgcgct ctcccgagaa
   232801 caatgtcgcc gcgtctcccg agggttcacg ggtcgtcgca accagcatgt cgacctgcga
   232861 ggtggccgac ggctgcgcca gagccacagg agccatcacg cctttcgcgt ggcctccgca
   232921 gcccgccaga agaacgaggg cgacaagcgc cgacacggtc gtgcttccgg ttttcgcgac
   232981 acggagcctg cctccgcacg agtttacatt acccaccaac gccacgcctc acaaactcgg
   233041 ggacgctgcc gcgccacctc tcatatcgac cgatcgcccg ccggccttgg ctaattcccg
   233101 taccgaacgc acgcacacaa atccccgatt cgcataaggg ctgcaaacct gaaccatcac
   233161 acggtttcat tgaggccatg cgatcgtctg ccttcgaacc agttacttcc ggtgagaaga
   233221 gcaccacacg gttcccccga agtgctccag agctaccgct ttcagccgga ctccgatagt
   233281 cctgagcatg cttagaagct ccaggacacg tgaagtttgc cctcccatac gtcgagatca
   233341 tcctgaccga ggcttagata acctcccgtc gcttcgatct ggaggttttc gttgagcagc
   233401 attctcaatc ccgagcgcag tgaaaacgcc cagggcgagg gagagacttc cgacaggtcg
   233461 cccgtcagaa tcttcccgtc gttcggccgc tcgaattcat attgcgcgcc aagctccgcg
   233521 aagaccagga acggctgccc gtccggcagg cggaagaacc tgctgacttc ggtcgacatg
   233581 tcgagcacgc cataattgta gctgtcgccc ggaagcgaaa cactcaccgg gaaattgaaa
   233641 agacttccgg agaggccgta tgcatcgctt ttgacatggg acagggttac ggatgctttc
   233701 ggacggacgt agtaggcgtc gaatttgtat tggccgttga gcgagatctc accggcaaaa
   233761 cgctcggaat catacttgcc gctgagcacg ctcagttcga catcgttgtt gtagcgtcca
   233821 taggtcaggg aagcgtcgat ggcccagtgc ttcgacaggc gataggccgc gtaaggaccg
   233881 aagctgaacc cgtccgaatc gatgtcgagc gagtcgtgga acgcatgcgt cgaactgtcc
   233941 tgcagagaaa atgacatgcc gaccacaagg tcgtcggtga tccggcgatc gaggcccatg
   234001 tcaagtgtgc gggcgaaggt gtcgctgtct cggtcgtaac gttcgtctga tatatccgtg
   234061 aaccgaatgt cggaccagaa attccagagc gagggcgcgg gcagatcgcg gccgggcgtc
   234121 agcggcacac cgcgggactg gccggcgcct tgcgtcgctg cctcttccgc aacgaactca
   234181 gggcagatcg gcacgtcgcg cctttgatcg gagcccacgg aacgggggtc gatgcagttc
   234241 tgcgctgtcc gagccccgac cacacgcccg ccccgaaccg ccgtgggatt cggtgagggt
   234301 gaaggtgggt cgaacccggg aaacacacgc ggcaggtcat tgtcgggccg cccatcggga
   234361 cggtccggcg gaatgcgcgg aagatcgttg tcgggtcgtt cgtccggccg atcgaaaccg
   234421 gggaagaccc gaaccggttc ggtgtcgggc cgcccgtcag gccgatcgaa gcccgggaaa
   234481 acgcgaatgg ggccggtgtc gggccgtccg gccggccgat cgaaatcggg gaagacacgg
   234541 atcgggccgg tgtcagggcg cccctcgggc aagtcgaaat cgaagaaccg aatcggaccg
   234601 atgtcgggcc gcccctgggg ccaggtgaag tccggcggaa tgaaatcgcg cacctggttc
   234661 tgcgtgtcga gcaggcaggg cttccctccc gataggtcaa gaagcttgtg cgtaccgccg
   234721 ttcccgttcg aaacgaccgg tgagagcgac agatggaggc cacgtttgct tttgctccac
   234781 gtatcgacca tctgattgcc ctgggcagcc tcaagtccga acgatccggc gctggtcccg
   234841 gaaagccaga ccgagcgggc tgcccctcgg gtgttcccga gataggccaa accgccgcct
   234901 gcactgcagt tcgcggcaga tgcctccccg ctccccacaa tgcaaaagag ccccgcaagc
   234961 agtgccccgc tcagcaccgt gctgaagcac ttccgaacct tggcgaccac catgcaaccg
   235021 accccgccca tcaactgacg cgtctgatac aacggaaacc gacatggctc gtcgtcgtat
   235081 cgatttcctg ggcatgccgt gccgcggggc gataccggcg gcaataattt ggtgcgcaga
   235141 gatgagagcc ccccttaagc acccggcgcg gcaccttcac tccggccgcg gggtcgacgc
   235201 tcgcttcgac atccgcattg cgcggattgc ttggaatgca gcaaggcttc gccgccgctt
   235261 ccgggtggcg tacggaccag tagtccgtgg tccactccca gacgttgccg atcatgtcgt
   235321 agaggccata tccgttcggc gggtagaacc gcaccggtga cgtccgcgcg aatccgtcct
   235381 ccatcgcatt ctcgatcggg aatctgccct gccaggtgtt ggccatgtgc ttcccgtcgg
   235441 ggacaagttc gtcgccccag gcaaactcag cctcgtcaag gtcgccgcgc gccgcaagct
   235501 cccactcggc ctcggtcggg agctccttgc ccgcccattc cgcataggcc tttgcgtcgt
   235561 cataggcgat atggacgacc ggatgatcca ggatggctcc gatgctgctc ttgcgtccga
   235621 gggggtgccg ccagttggcg cccagggtga agatccacca ctgcgatatg tcattcccct
   235681 gcagcgggcg tttcggcggc gtgaatacga gcgagccggc tctcagattg gatggcgggg
   235741 cgcccggata gtcttcggca cgcggctttt tttccgcgaa tgtcacatgg cccgtcgcat
   235801 tcacgaattc caggaactgc cggttcgtta ccggtgcctc atcaatccag aatccgtcca
   235861 cggttaccgg gtgggccggt gcttcctccg gataatggtc gttcgatccc atcatgaagg
   235921 tcgcaccggg aacccagacc atctccgccg cgggttcaag ctcaaccacg ctgttcaaag
   235981 aagccttcat cggtcatctc ccctgcaacc aattcctgcg tctgccgtga cggcagcgcc
   236041 ataccgtttc aagcctgcgc atcttgtccc agggtcgccg ccttgtccgc atgcacctgc
   236101 ccggaacgcg ggccgcagcc cacataatat ctaccggtgt tgccgaccta ctgcacgtta
   236161 gacgcacctt acgattgcag cggcccttct caccccggcc gagccggtga tccggttcca
   236221 gttcccccct cagtccggga cgaccatcca ctggtcgccg gggttgaacg tgcggatgtc
   236281 gacggcagtc ttttcggtat ccccgccgag atccgcctcg tatacaattc cgttgcgatt
   236341 gaccacgaag gtcttcactc ccgtgacgcc gtatctcacc ggccaagcaa ccagaccgaa
   236401 accggcgatc atgttgccgt tgatgatata gtcgaatttt ccgcccgcaa tattgtcgcc
   236461 ctggcctgtt agaatacggt agcggtaacc ctggaagcct tcgccggcct tcgcccgttc
   236521 taaggcatca ccctctgcaa gcgccgcagc agcggggctc tcctctccgc cgaactcctc
   236581 agcgggccag tagaggccat cctgcgcgcc cttttcgctg atcagctttt gggcgtattc
   236641 cagaactcca tcgccgtcat ggtcgccgcg cgcatattct tcctgcgcgc caacataggc
   236701 gcgcatcgtg gcaatcgtgg caagctcatt atcgccgacc cggcggttgg cgatctcttc
   236761 taggccgaca taggtgtcga acgcccactt gccgtcctcc cctttcgaga ccgggaaggg
   236821 aaacggccac cgctcgtcgc cgatctcgat caccttgcgg ccttccacat cttcgacggc
   236881 gaccttttcg tttacgcctt cctgtatgtc ggcataggtc tccattacgc cctcgctcga
   236941 ctttgtcttg gccgggtcca gacccaaaag caccgccaat ttgtcaaaat cgccgccatt
   237001 gacggtctct ttgaacgcct ccaccgcctt ctcaggcgta tcgaagacag gcggatcctc
   237061 tgccgcggcg tattcggcaa gcggcgcata gtcgcctgct tcctgcgcca gggcggcagg
   237121 taccagcaca gcaggtgcca aggcggcact gccaagaagg agcatcccga agaaggagag
   237181 tgcgatctct tcacgaatga tcttggtcat cgtagtctcc cgatctgatt accgccgacg
   237241 tccaccgcca cgcttcaccg ccttgtgtcc gcccccgcct cgatggccgc cgcccatgga
   237301 atggtgtccc cgactggaag agatatgcgt ttgccgcttg ttgccgacct tgccgagggc
   237361 cgaatgcttt ccgccggagg agtgccgtac atgcgctcca ggtctcggag catgcgcctt
   237421 ggggtgtacc ttcggccggg cgccggtggc tttgccggtg cttgcgcgtg cccggttcac
   237481 agccgctcca ccatcgcggc gcggcgcctc tacacgccgc tgggtatttt gcggccggtt
   237541 gcgttcagcc cgaacgcggc tcgcatcgac tttgctcttg cggatgtcgt cgacggaaac
   237601 cttgccgggt ctgcgggcaa tgtccccatg gtcgcggcgc acatccctcg cacgattggc
   237661 gatgttgttg cctcggttgg ccttgaagtc gtttttgaac ttatcccgat cgatgttcgc
   237721 caactgattc ttgtcgaact tgatcttgga ccggtcgacg ttcttccagt cgacgtcgtt
   237781 catcttgaat ttatctcgat cgacatcgat gttgttgaaa caattgtcgc aatcgatgtc
   237841 gacgtcgctg tcccagtgcc cgccccagac gccccagtcg tcccagtcga ccgccgccgc
   237901 ccagatcgca gcgccggtga tcgcggcggc aaaataaggc gcggacggat agtagtagct
   237961 cggatagggg tcgggataat aggcgactgg cgccggcgca tagcccggct cgtacagcat
   238021 ttccggctcg tatctcggaa cataaatctt ttccggatcc gccgcctgga ttacgatatt
   238081 gtcgccctcg ttgacgacct tcagcttgtc gtcgttctta atcacgccat ccgccacagc
   238141 cttgtcgcgc agggtctgaa ccgcgatgag aacgtctttc tgctggtagg cgagcgcgct
   238201 tccgagtgcc tgcgtccaat cgaggtcgtc gctcatcatc ttgacgatct cgggatagtt
   238261 gagaagcgat atcacgctgt cgtcccagct gtccttcggc tgcagatcct tgttggtctt
   238321 cttctcttcg agaaagcgtg cggcttcgac gatctgcaac ggatagagcg acgcggagct
   238381 gacgagcgcc acgagttcat ccgggtagag cgcgatgcgc gcaaccatag tctcgagctc
   238441 ttcctcggtc aggaggtcgg cctgttcatc gccggtcgca cccgtctgac cttgggccgc
   238501 ctgctgggca agacctcggg gaaccaaggt cgggccggca gccatcaaga ttgcgagccc
   238561 cgcaacgccg atcggacggg cgatcagtct gagcaactca gtcggcatag cctcactccc
   238621 tgcgctttgc acttcagatt actgtctcga gcgaccgctc gatctggcct catgcattgc
   238681 tctgcggcgt ccccgtcagg agcgccggtg cagagcggat cgcaactttc cacgaagctc
   238741 ccgcagcgtt cgccgcggac gccaatcatt tcggaaacag gaacgtgact gcaaggcgcg
   238801 ctccccagcc ctgcggtcca ttatccggtg ccgccgccca atagcgggcg ccggctgtga
   238861 tgctcaccgg ctgttcgccg aatttgacga gcttcgacac ctggaagttc accggcacgg
   238921 accattcgtc gctctcccag tcataggtgc tttcggtatt gacggcgaat gtccacgcat
   238981 ccggcgtcgt gtaggaaatg aagggctgca ggaaggtcga gttgacatcg gccctgtctt
   239041 cgttgcccgc aaaggaccag atgtgattta ccagcgcacc ataggtccat ggaccgtcct
   239101 gcttcaaagc gacggcggtc ggcccgacgc cccatttttt gctgccaagc agatcgtccg
   239161 ttcccgtcgg gaggagaaag accgggccaa acccccagat aattccgccg gctgtcggat
   239221 ccttgggcga gaagaagaag ctctgcacgg tatcgccaag gccgaactga tcgcccgagg
   239281 ggcctgcgac gtcgctctgg gagatgaccg gcaggatcgt tcgcgagatc aggttccagt
   239341 cttcgttgag cgagattggt atgactggct gaatgttcaa cgtgacccga tgaccatcat
   239401 ctggaccaaa gccgcgatcg tagttgagct gaaatggaac gctgatcagc gaagcgactg
   239461 gattggacag ttgcttcgcg aggttctcac ccgaggcatc ctgcgcttcg gcagcaccgc
   239521 aagccgcggc agtcgcaacg acaaacgccg ctgcatagcg ccaaccaagg cccggcgtga
   239581 ctgccttgcg tccagacccg ggtaaaccgg atcgtagaca gccaggataa tccatggtct
   239641 ctccttgcct gaactgcgca ccacggcacc cgtccgggtg cggcacccta accttacccc
   239701 ggtgctgcct gtaccgcttt gcccgtttca aaaggacgtg aaaaccggaa aacggtcgga
   239761 ctcaacactc gagaacttaa aggccgaagg ctcgcaacaa tcgccgatta cgcggcgaaa
   239821 cgggagccgg caagttggcc tttggtccaa ctaccgctcc tctgaaaagc ccggatgata
   239881 ttggtgccgg cagcgccgac gtggcttccg atcgagcccg cctcccagtg cgtcttatag
   239941 agaatggagt gatcccaatg aaaaaagaac cgattgcgga ccagcgtgat ccacgcgagc
   240001 gcgccaatat cacgcggcgc agcattctgc ttggcgggac tgccattgcc gcggcatcga
   240061 ccgtactgac aaccggcggc gcgcagaccg cccaggcgca gacgcaaacg caagcgccag
   240121 atgccggcgg gtccgccaag cagccgaaca tcctggtcat ctggggcgat gacatcggca
   240181 cctggaatat cagccataat aatcgtggca tgatgggcta taagacgccg aacatcgacc
   240241 ggatcgctca ggaaggcttg tccttcacgg attattacgg acagcagagc tgcacggccg
   240301 ggcgcgccgc tttcattggc ggtaatgtac cggtgcgcac cggcatgacc aaggtcggcc
   240361 tccccggcgc gaaggaaggc tggcaggaga cggatgtcac gatggcaacc gttctcaaga
   240421 gccagggcta cgcgacgggc cagttcggca agaaccacca gggggacagg gacgagcacc
   240481 tgccgaccaa tcacggcttc gacgagtttt tcggcaacct gtatcacctc aatgcggagg
   240541 aggagccgga gaaccgcgac tatccgaagg acccggaatt ccgccgtcga tttggcccgc
   240601 gcggcgtgat ccattccttc gccgacggca agatcgagga taccggcgcg ctcaccaaaa
   240661 agcggatgga aacgattgac gaggagtccc ttgctgcggc caaggatttc attacgcgcc
   240721 agaaccaggc aggcacgccc ttcttcgtct ggtggaacgg cacgcgcatg catttcagaa
   240781 cacatgtcaa ggcggaacat gccggcatat cggggccaag cggcgacgag tatcacgatg
   240841 gtatggtcga acatgacatg catgtcggcg agttgctcaa gctcctcgac gaactcggta
   240901 tcgccgaaaa tactgtggtc atgtattcga ccgacaatgg acctcatttc aacacatggc
   240961 cggatgccgc cacgacgccg ttcaggagcg aaaagaactc gaactgggaa ggcgcctatc
   241021 gcgttccggc tttcgtgcgc tggccggccc ggttcccggc aggcaagact ctcaacggta
   241081 tcgttgctca tgaggattgg ctgcctacgt ttggcgcgat tgccggtgca ccggacgtca
   241141 aggaaaagct cctggagggt gtcgaactca acggccgccg ctatcgcaac tatatcgacg
   241201 gctacaatca gctcgaatat ctggaaggca agaccgacca gtcgccgcgt cacgagttct
   241261 ggtacgtgaa tgacgacggg caggtcgtcg ccgcgcgcta cgacgactgg aaagtggtat
   241321 tcctcgagaa tcgcggcgaa gccttcggcg tctggcgcga accctttacc gaattgcgcg
   241381 tgccgctctt gttcaacctg cgacgcgacc ccttcgagaa ggcgcagcac aacgccaaca
   241441 cctatgatga ctggttcctt gaacgggcct tcgtcgtggt gccgatccag ggtctggcgg
   241501 cgaagttcct gcagacgatg aaggaatatc cgccaagcca gtcacccggt tccttcaatc
   241561 tcaccaaaat cgaagagagc ctgaaggccg ggatgagaaa ctaacggact tagctctgaa
   241621 tggtgtgggg ccggcgccaa atggtgtcgg ccccattttc tggggtgacg cgccaggttc
   241681 gcgccggata gctcatcatg cggggtcgct taagataagc ctattcgctg caaattgccc
   241741 caaggtccaa cttccatgcc gtcgaggtaa gtcggacaat cagtgatccg gattgaacca
   241801 aggcaatgcc gctgtggtga tgcggcggtt ccgattcgca aagaatacgg ccaggagtga
   241861 gatcatgttc caagtgaccc gccgctcggc gatgaaaatc gccgcgctcg ccgctgcagc
   241921 ttcgtccatg ggccaggctg cgtttgccgc cgagccttcg atcctgccct cttgggtcga
   241981 tggcgacgct aaggctcgca tcatcgactt cgtgtcggcg acgaccacag agggcggccc
   242041 cgatttcgtc gagccggccg atcgcgtggc ggtattcgac aatgacggaa cactatgggg
   242101 cgagcagccc atgtatgtac agctggcctt tgcactcgac cgcgtcaagc aactggcgcc
   242161 gcagcattcc gaatggcaga cgacggaacc gttcaaatcg gtgctggctg gcgacatggc
   242221 gggtgtcgcg gccagcggcg aacggggact gatcgagctt gtcgccgcta cccatgccgg
   242281 catgtccacg gaggaattcg agaggatcgt ttccgactgg atggaaagcg cccgccaccc
   242341 ggcgtcggga aaaccctata ccgcgcacat cttcaagccg atggtcgaat tgatcgacta
   242401 tttgaagtcc aaccagttcg aggtctttat cgtctcgggg ggcggcgtgg agttcatgcg
   242461 tccgtggacc gagcgcgtat acggcatccc gccgcagaac gtcgtcggat ccagcataaa
   242521 aacgaggtac gagctgcgcg acggtgttcc ggcgatcatg cgtctgccgg aaatcgactt
   242581 catcgacgac ggtctgggca agcccgtcgg catcaacaaa ttcatcggca gacgtccgat
   242641 cgccgccttt ggcaattccg acggcgattt cgagatgctg gaatggacga ctgcaggccc
   242701 cggacgccgg ttcgggctga tcgtccatca cgacgacgca gagcgcgaga aggcttacga
   242761 ccgcgactcg cattttggcc ggctcgcgcg cggcctcgac gaggcgcccg cacgcggttg
   242821 gaccgtcgtc agtatcaagg acgactggaa gctcgtttac ccggagtgag acaggatagg
   242881 gcgcgtccag atgagcggga tggcgaaaac tttgcgcggc tttccgcgcg taccccgctc
   242941 tggcctaacc attagatttg atcacgttcg tgatgtgctc cgggcccgcg gctcattggg
   243001 agcgtggcgc ctttgcgggg cgctgatcac ctcgcagggc ctcgatagcc gatgaaagcg
   243061 tgtcgcggga aagcggcttg ttgaggaagc ccgaggcgcc ggctcgcatg cagctttcgc
   243121 gcactccctc ttcatccgcg ccggttatga cgatgacggc caacctcgcc cgtcgtgcgc
   243181 tgagctcgtg caatacgtcg agcccattca tgttcggcat gtgaaagtcc aggagcacgc
   243241 aggacgggct ggtctgttca agctccttca gaaacaattc gccggaggca tacgcgactg
   243301 gtttcaacga caatgactga acgagacggc aaagcgcgcg acgaaccagt tcgtcatcat
   243361 ccacaatcgc aataatgcgc tggctctcgc tcatatgtca gtaatatatc aaggcctccc
   243421 ctaatcgtag ttggacttgg gcccaatgcc gccatgcatc gtttctgcgc cggacacgag
   243481 gcgcacgagg tcggcaaccg tccgcacgcc cagtttcgac atcatgcggc cacggtgaac
   243541 cttgatcgtc ttttccaccg tcccgagatc ggcggctatc tgcttgttca ggaggccgga
   243601 gacgacgaga tgcatgacct gcgtctcacg ggccgtcagc cggtcgatcc gcatcgccac
   243661 attcgccttc ttctcttcgg tctcccgacg cgaacgtgca cgctggagcg ccacgtccac
   243721 ggcttcgagc agagcggcgg cctcgactgg tttcgtcagg aagtccacgg cacctgcctt
   243781 catcgccctg acgctcgccg gaatatcccc cttacccgta agaaagacga tcgattggct
   243841 cccgcctgct gcagcgagtg cctcctgcac gtggaaaccg tcggagtccg gcagcccgag
   243901 gtccagaatg atgcaatcgg ctgtgtcgag atcgtcgcaa gcaagcagct cgctggcgct
   243961 ctgatacgta cctaccaagt atcccgaagc cgaaagcagt ctcttcagag accgcagcac
   244021 gagctcgtca tcatccagca gcaatactct accaacgctt tcccgcatca cgcacctcta
   244081 ggctgacggc agaataatga tggcccgcgc tccccgcttc acaccatcgt caaagaacaa
   244141 tttccctccc tgcgcctcaa caatgcttcg gcagattgca aggcccagac caagaccgcc
   244201 cttcttcgag ctcacaaaag gcttgaacac ctcgccctgc attcccgccg gtataccagg
   244261 ccccatgtcc gcaaccgaca attcacaata tccattgttg cttctgtcga ccgcgatttc
   244321 aacctttcgt tgcttgggcg ggatgtctgc catggcgtcg gccgcattca cgagcaaatt
   244381 caggatcacc tgctggagct gcacgaggtt cgccttgacg cggacgctcg ccaattcgtt
   244441 tttgacttcc acctcggtgc ggcgcgccaa catctctgcg tgagccaggg caacggtctg
   244501 gcgcacggcg tcgttcaggt cgaggatttc ctgcgaggct tcgcccttca gcatcatgct
   244561 gcgcagttgc gaaatgaccg acgacgcccg ccggtcgtcc gccacgatgt catcgaagat
   244621 cgcgcggatt tcgttcatgt ccggagcggt ctcggtggcg agcctctgcc ctgcctcggc
   244681 attggcgaga atagaagtca gcggctgcgt cagttcatgc gcaaaagccc cggaaagctc
   244741 tcccagttgc gatctcctcg agaggtgggc aagctccaca cgttcggagg cgagggtcgc
   244801 ttcgagcctg cggccccgcc ggttctgata gacgagcgcg gcaatggtga gcatttgcgc
   244861 tgcgatcacc aggagtgccg cgctgatggg cagtcggtaa cgctcccaaa cgcttggcgc
   244921 ataactcagg atttctgcat cttcgggtat caatacgtcg tcaattccca ggcgctggac
   244981 ttcgcgccag tcgacaagcg ccgtctcctg cgcgggcgtg gtccggggag ccgaaaggtc
   245041 gcctcgcatg acatccaggg aaagagcggc catttgagcg ccgatggatg gaaacgtgcc
   245101 cacatagccg cccagtactc tgaagcctaa ataggaactg tacacaccat agacaggcgc
   245161 gccagacgct gccgcgatcg cccttgccgc gtcccgcggc acaaatttca ttccctccgc
   245221 atcttcaaag acggtcagaa tcacgagcgc cgcatcggag ggcagttccg cggccgtctt
   245281 gcggaaacca tcgagcgaaa ggccggaaac atattcgacg tcaaggccgg cgtagcgctc
   245341 ccccaggacg gcggtcgctg tgtcgcccca tttgcggtcg aagggcgccg agccgtacat
   245401 gacgaccacc ttgcgcgccc tcggttgaag ccggctggca agctggactg tcttgcccac
   245461 gtcaaaacgg ctgacgacgc ccttgacgtc gggcggcagg ttgccggtaa cggaactttc
   245521 ggtgactgca ccgaagacaa cgggaacatc gttggcaaaa cgctcacgcg tctccagaac
   245581 gaaacgcagc gcgccggggc cggccgccac cacgacatcc agattcaact gccggtattt
   245641 ggcctccaga aagcctgcga gacggagcga gtgctccggc gatgagaaac gaagggtgtc
   245701 gagatactcc gtataatatt cgacatgccc ggggtcgttc gcttccatgt attcctggaa
   245761 accggacgcc aattgcatgg cggcaaccag ggtgctttcg ctttcataga tcagaagtac
   245821 gcgtcttggc tcggtggcat ggcagaccaa tgttcccgct atcagcgcga acattgtaac
   245881 gatgaccgtt tgcggtcgaa ttcgcagcac catgcccctc cggccgagtt catgcagcca
   245941 accggcacac cgaaatacaa tgggcaccat gtcgagccgg tgacaattca tcgttgtgcg
   246001 acgtgatcga ctcaattgca agccatgaag tcttaggggt tttgcggact gccgcgcctg
   246061 cgtccgcgat tggcccttgg tccatctatc gcttatgccg aaaatcgccg aaggataaac
   246121 cataagcgcc cggcgcataa aggtgccgac tgaattcctg agcaatgaac tatggtgatc
   246181 atgagcgtga acggtgcttc acatccgtcg acggacaatg acgcggtaga aaacgccccc
   246241 tcttccggtc ttgccaactt tcgcgcgtcg cacggcggac cgtttttcga gctgcaggcg
   246301 cagttgaaac tccttcggga aaacacgctt cggtcgggcg caagggctat ccttttcgtg
   246361 gcgctggcct ggggcgtgcc gtttctgctt ggcattcccc gcagcttctc actcgatcac
   246421 agtcaaaatg cttatctcgc ggatcccgga gtatgggcga agttcttcat cgggatcggc
   246481 gccttcatcc tggcggagca gcaggtcgag cgcggcctca ggacacgcct ttcgcaattc
   246541 atccgcgcgc cgattatcgc gccgggcgcg gtcgaggaag cagggcgcca attgtcggtg
   246601 gcgttgcgac agagggattc gcgcggagcg gaactcatct gcctcgcgct tgcggtattc
   246661 gcagcagccc tgtcctactt caactttcac acggtcgacg tatcctcctg ggcggtcgaa
   246721 catcggcccg agggcaacag gatcactgcg gctgggtggt ggtcaatctg catcagcctg
   246781 cccctcttcg tttttctttt tctgcggggc atgtggcgac acttcgtctg ggcgaacctg
   246841 ctgcgccgca tcgcgaaaat ggacctgcgg ctcgtcgcca cccatcccga cggcaagggc
   246901 gggctcgcct tcctggcgca gtacccgaac gcatatgtct tcttcgtctt cggcatgagt
   246961 tcggcaatcg ccgccgcaat tgctaagaat attctgcagg aaagcctttc gatgacgacg
   247021 ttcagcatgg tcatgaccgc ctggctggcg atcgtcgtcg cttttttcgc ctacccgctt
   247081 tctgcgttca ctccgccgct cgcccgcctg aaagaaaacg ggctggccct gctcggagcg
   247141 caggcgacgc gctatcaccg ggcagcggag cgcaaggctg tcggccgaaa catcttcgaa
   247201 gatccgacgc ctgagccggc cgacgaaatt gccgatccga gcaagctttt cgaggcgacg
   247261 cggaagctca agacagtact cgtcagccgc gaggcggtcg tgccggtggc cgctgccgca
   247321 ctcataccct tcgccgtcgc cggcgcgacc agactgccat acaaggaggt cttttccgtc
   247381 atgaagaagc tgctccttct gtgagggcgg ccatccaggt ccgacagagg gagtcccagt
   247441 agcgagagcc ggatctcgac ccggaatttt cgagtgtacc catagtcttc cccaacgacg
   247501 gtcaaaaatg gacagacatg tttttcacat cggattccag cgggggcatc agtgacattc
   247561 attcagtctc ttctgcacca gtctcccgaa atcgcgctgt tcctggcgct cgcgggcggc
   247621 tattggatcg gcaagttcca gttcggcaag ttccagctcg gcaagttcca gctcggcggc
   247681 gttgccggtt cgctcctcgt tgcagttttg atcagccaga tcggcgtgac tatcggcaac
   247741 gggatcaagg ccgtcctgtt cgcgctcttc atatacgccg tcggcttcga gagcggcccg
   247801 caattcttcc gctcgctcgg ccgccaatcc atacgcgaga tcatcatggc cgcggtgctg
   247861 gcgatcaccg gcctcgtcac cgtcgaatgg ttcacgggcc gcagcatccg cgacgacgcg
   247921 atcaaggcgg aagcagagat gctagcgggt gccagcgtct acggcgtcgg cgaacagcct
   247981 gcgctgccca tgctggtcgg tcgtcttttc agcgtcgaga gggcggccgg cagaatcatc
   248041 tccgaactcg aaagaaaagg gccggctgcg acgatctcga tcgaacgcgt caaacgcggc
   248101 ggcaagctca tcggcaacga cccgggactg gtgcttgaaa aaggcgacat cctgcttgtc
   248161 gtcggccttc tgataggcct cgtgatccgc cttggatcgg tacccctgac gctcggtggc
   248221 ggtggcggtg cgcttctctc gcgtctcgtc ttcggctggt tccggacccg gaacatggcg
   248281 atcgcaggtt gaaagttgaa ggggtccgaa tgaccttggc gcgaaatttt ttcttgatgt
   248341 agcctagacg tgcacggcgc cgtgcgcctc gccgaatagc tcgaatgcga acatgcatat
   248401 gggaaggaca gagggaagca ctatgggaaa ccgggaagac atccaggcac tcggcaaaag
   248461 aatcggccaa tcgatcatcg gtcaggaggc gatgatcgag cgtctcctgc ttggtctgct
   248521 cgggaacggt caccttcttg tcgagggtct gccagggctt gccaaaacca gggcgatcaa
   248581 gagcctggcc aagaacctcg aagccagcct gtcgcgcatt cagttcaccc ccgacctgct
   248641 gccttccgac atcaccggat ccgaagtcta tttcagcgaa ggcggcaagg gcgagttcaa
   248701 gtttcagcag gggccggtct tcgccaatct gatccttgcc gatgagatca accgtgcgcc
   248761 ggcgaaggtg caatcggctc ttctcgaggc gatggaggaa cgtcaggtca ccgtcggcgg
   248821 ccagagccac ccgctgccgg ctctcttcct tgtcatggcg acgcagaacc cgatcgagca
   248881 ggaaggcacc taccccctac cggaggctca gctcgaccgt ttcctgatgc atgtccgtgt
   248941 cgactatccg gacgcgaatt cggaagttgc gatcatggag ctcgtgcgct ccgaggaacg
   249001 ggagcctcac gccaagggcg ccgaggcgca gaagcttgcg gccgaggtgg tgctcgccgc
   249061 acgccgggaa atatcggaga tcgcagtctc caggccggtc gaggactata tcgtcgcgct
   249121 cgtcatggcg acgcgctatc ctgacaagat cgatacggaa cttgccaaat ggatccaggt
   249181 cggcgccagc ccgcgtggcg tgatcgggct cgacaaggtc tcgcgcgctc acgcctggtt
   249241 gaaaggccgc gatttcgtga cgccagatga cgtacaggct atcgtgcacg acgtattccg
   249301 ccaccggctc gtgctctcct acgaggccca cgccggcggg gtcacagcgg accaggcggt
   249361 cgaccggatc gtggagaagg tggcaactgc ctgattggga ggacttgcga tggcaatttc
   249421 tctgcccgca ttcggaagaa cgaaggaaat cctacgtcgg gccgccggcg cttcagacgg
   249481 tgcctacgtt tccgtcgaca atctcgtggc gctcgaatcg atggccgccg acctgacatt
   249541 cctgcgcaag gcccccgtcc gccgcttcct tgccgggcgc catgaatcgc gcatgcgcgg
   249601 ccgtgggctg agcttcgagg agcttcggac ctacatgccg ggcgacgata tccgcacgat
   249661 cgactggcgc gtcaccgccc gaacgggtca acctttcgtg cgcgtctata acgaagagaa
   249721 ggaccgaccc gccctcgtca tcgtcgacca gcgcaccaat atgttcttcg gcagccgccg
   249781 gtcgatgaaa tcggtggccg ccgctgaagc ggcggcgctc tgcgcctggc gcgttatggc
   249841 gcttggcgat cgcgtcggcg gcgtggtctt caacgacctg aagcaggagt ccatccggcc
   249901 gcaccgcagc cgcggatccg tcatccgctt cgccgaaacg atttcgctcc agaacaaggc
   249961 acttagcgcg ggctcggata tcgagagggc gcccggtcaa ctcaatgccg tcctgggcaa
   250021 cgtcgcagcc gtcgcgcagc acgaccatct gattatcgtc atcagcgatt tcgatgggca
   250081 cgggccggag acacgcgatc ttctcttgcg gatgtccgtc tcaaacgacg tcattgccat
   250141 cctcatctac gatccattcc tcctggacct gccgcgccag ggcgacatgg tggtgagcgg
   250201 cggcgctctg caggccgaac tgcagttcgg ccgtagcaat gttcgcgatg cggtcgacag
   250261 ctttgcgcgc aacagaggcc gagagctgct ttcttggcag gaggagatgg gcctgcccat
   250321 gctgcccgtt tccgctgccg aggaggtcgc cccgcaattg cgcacgcttc tcgctcaact
   250381 cgcctggcgg caaaggaggc gatagatgga tccgacccca gcgcccgatc ctatgctcgc
   250441 cgctactctg cggcagatgg cagacatcgc cttgcctccg cgagtctcga tgctgccggc
   250501 cacctggggc tgggcggcac tcttcggatt ggtcgcgatc gtccttgcag ccgtcctctg
   250561 gcaccgactg cgccagtaca agcgcaaccg ctatcgccgc gaggcgctcg ccgagctttc
   250621 gcggttcgag aaggaagtcg atcagccgtc gggacgccgg cacgccatgc agagcctccc
   250681 tgccctcgtc aagcgcacgg cccttgcggc ctggcagcgg gaaacagtcg cttccctaag
   250741 cggaaaggaa tggtccgatt tcctcgaggc tcatgccgga agggcgagga tcgacggcga
   250801 ggcctaccgt ttcttcgctg aaagcgaata ccgcccggcg acgctcgccg caatggacga
   250861 agccactgcg cgccagaggc tcgcgtccgc acgccaatgg atcgagggtc acaatgtacg
   250921 tccttgatca tccctggctc ctgctgcttc tgccggcacc cctgttcgtc tggtggctgc
   250981 tgccgcccta tcgggaacag acgccggcag tgcgcattcc ctttttcgag gacatcaccc
   251041 gggccgctgg catcggcccg acggaaggct cggtcgtgcc gcgtgccaac ctcctgcaga
   251101 agatcatcgc gccgatctgc tggctcctgg tgttgacggc gcttgcccgg ccgcaattcg
   251161 tagagccgcc gatcgagaag accgagcccc agcgcgatct gatgctcgcg ctcgacctct
   251221 cgcaatcgat ggacacgcgc gacttcagcg acccgcaggg caatcttcag gcgcgggtag
   251281 atgcggtgaa gaccgtggtg gcagactttg tcgatcgccg tccgtatgat cgcctcggtc
   251341 tcgtcgcttt cggtgacgcc ccctatccgc tcgttccctt caccatggat catgccaccg
   251401 tccggtccat gctgaccggc gccttaccgg gcatggccgg cccaaaaacg gctctcggcg
   251461 atgcgctggg gctttcgata aaactgttcc agcagagcca ggctcctgac aaggtgctgg
   251521 tcgttctgac cgacggcaac gacaccgcca gcaagatgcc gccggacaag gccgccgaga
   251581 ttgcgagcca gaaccacatc cgtattcata cggtcggcat cggcaatccc gacgcccagg
   251641 gagaggaaaa gctcgatacc gagacgctgc aaaagatcgc cacggctacc ggaggacgct
   251701 atttcttcgg tcaggaccag caagcgctcg ccgagatata cacgctgctc gacagcatca
   251761 caccggcgaa ccagaaaacg ctgagctggc gcccgcgcat cgagctgttc cactacccac
   251821 tcggcgctgc cgtcctcctc gtactcggct atcatgccct aatgtggctt ctctcggtta
   251881 gtgccgcccg caggcgaaac aacgaggctg aagcatgatt gccgatttcc attttctccg
   251941 cccctggtgg ctgctcgcgg tcctggcagc gggactgctc gtatggctga tgcggcggca
   252001 atcggacatg cggtcccgct ggaagcacct gatcgctccg aacctgctcg atcatctcct
   252061 cattgaccgt ggccggcaga gcggatttcg acccgtctac ctggtcgccg gcctgatcgc
   252121 cctttccggt cttgccgcgg ccggacccac atgggagcgg gaacgtccgc ccttcgtcga
   252181 agacaccgcc ccgctcgtca tcgcggtcga cctcggccca acgatgaacg ccaccgacat
   252241 ctcgccgacg cggctggagc gcgccaagct caaggtacgc gacatcatgg caaaacggaa
   252301 aggtgcccga accgcattgt tcgcctatgc aggctcggct cacatggtct tgcccctgac
   252361 cgaagatgcg tcactcatct ccacgtacct tgcggcgctg tcgcccgcac ttatgcctgt
   252421 cgagggcaag aataccgcca aggcgctcga agccgccgag gcagctcttg cggacgagcc
   252481 ggcgccaggc acgatcctct ttttgaccga cgggatcgag caaagcgcct tcaccgcctt
   252541 ttcgcagtat gagggccgca acgacctgat ggtgctgggt atcggcacgg aagcaggcgg
   252601 acccgtgaag accgaaagcg gcgcctatct gacagacggc accggtgccc gcgttctggc
   252661 gcggctcgat gtcgacgcac tgcaagaact caggtcttcc tcttctgcgc aggtggcgac
   252721 ggtcaccctg gacgacggcg acgtcgactg gatcgtccgg cgcattcaga cgtccttcgc
   252781 acaaagaacg gaggaaggtc tgacccgctg gcgcgatatg ggatggtatc tgaccatagt
   252841 ggtcgcgatc ctcgtcgcgc tcaccttccg ccggggtcat cacgtccgct ggctcgggac
   252901 cgtcgtgctc atcctgtcgt tccacatgcc cggacgggcg gaggcggcgg acttcatgga
   252961 cctgtggctg acgcccgacc aacaagggca gcgcgccttc tcacgcggcg actatgctgc
   253021 cgcggccgaa catttttccg acccggaatg gcgaggcgtc tcactctatc gcgccggccg
   253081 ctatcaggac gcaatcgacg catttgccca gtcgacggca cccgagagct attttaacca
   253141 gggcaattcg ctgatgcatc tcgacaagcc ggaagaggcg atcggcgcct atcagcaggc
   253201 gctcaagcag cgcaccggct gggccgaggc aaagaccaat cttgcgctgg cggaacgccg
   253261 caaagaggaa aaggacaagc aggaagacga caagcagcag gaggcagcgg ggctcgatcc
   253321 cgacgaagtc caatttgacg acaaggccaa gcacggcaag gagggcgagg tccagacggg
   253381 cgcacagacg gccgagatgt ggatgcgcaa cattcaggtt tcccctgccg cccttctggc
   253441 gcgcaagttc gcgatcgaag catcgcagga ggaccgccaa tgacgatcgc ggccccccgt
   253501 ttgtaccgtc ttcttgcagt cctgttctgc tggctttcga cccaaggccc ggcactctcc
   253561 gccgatccgc tcgcccgggc agcgctgcag tcgcagggaa cgctctatgc cggccagcaa
   253621 atccttgtag acgtcgacgt cctcgtcccg aactacttcc tgcaatcgcc tcaattcccc
   253681 gcaatcgata ttccaggcgc gatagtgacg cttgacgacg gaagggcact gaacctcaac
   253741 gaaacgatcg acggaacgcc ctattccggc attcggcgca cctacataat agtaccgcag
   253801 gcggccggcg attttacctt gccccccgtc ccgatcacct tcggctatgc agcggtcccc
   253861 cctcaggcca cccggggcga ggtcacgttt ccgccgcttc gcttcacagt tcgaagcgcg
   253921 ccgggcaccg ccggcgatag tcccggtatc gttgcggcaa aagtcagcgt cagccaggaa
   253981 ctggatcagg atccggcgca gttgaaggct ggcgatacga tggttcgcac ggtcacggtg
   254041 cgggccgaag ggcttcgcgc catgatgatc cccgaaccgg actttacggc tcctcagggt
   254101 gtccgcctct accggcagga tccttcactt tcggaagaga cggaccgcaa cggccagtcg
   254161 atcgcgggcc tccgcaagga cgttgcaagc tatctcttcc aagacgccgg caattatgtt
   254221 ctgcctgccg tgaccgttag ctggttcgac ccggcttcgg cgaagaccca gtcggccacg
   254281 gctcccgcgg tcagcgtgac ggtttcagcg gcggccgccc tctcccctgc tcttgcgccc
   254341 cccgcgccgg agccgcaacg cgatgccttc gactggctgc acctggctct gatcgggggg
   254401 atcgtgcttc tcaccgcctc ctcgctttgg gttgccgcca acggattgtc ccggctggaa
   254461 gcctggtggc aagagcgccg ctcgagagag cggcagtcgg agccggcttt tttccggcaa
   254521 gtggagcagg cgtgcaaaag cggccgagac gacgcgatcg cgcgcgcgct cgacgcttgg
   254581 tcgcgcaaag cgggagcgat gccgctcgaa ctttggcttg ggcgcttcgc ggatgccgag
   254641 accaagcagg tttaccaggc ctggcagaga acgcgttacg cttctcagca agcatcccag
   254701 ccgttaggag caggcttgct tctgcccggc ctgaagaagg ctcgggaagc ctggttgatg
   254761 caggaaacgg aagcgcccgg ccgcaagccg gccttgcttc ccctcaaccc gactatgccg
   254821 tgacgcgaag gatgaaagcc gacttgtgag cccgtgttat gataccgggc cgggaatcgg
   254881 ccgtgatcgg gcgttctttt cccaatcccg ttttcacgcg cagaccttgt cgggaggtgg
   254941 catttggccc agcgtttcac agtgaatttt ccggtattcg ccgggtcggt gaccgtcatc
   255001 gcccttttcg gcgcaatcgg ggtggttgcg cccaagagag ctgaatccat tttcagcggg
   255061 atccaggcga cgatcctctc cggtttcggc tggctctatc tgctcgcagt ggccatcttc
   255121 ctgttttcga tgattttcat ggcatttagc cgctataacg aattgaagct cgggccggag
   255181 gattccgaac ccgagttccg ctacctgtcc tggatcgcca tgctgttcgc cgccggcatg
   255241 ggcatcgggc tcatgtactt tgccgtcggc gagccgatga cgcatttcgc ctctccaccc
   255301 gaggccgaac ccttgaccat cgctgcccag cgtgaggcga tgagcgtaac cttcttccat
   255361 tggggcgtac acgcctgggc aatatattca gtggtcggac tgtccctggc ctatttcggt
   255421 taccgctaca atctacccct cacggtccga tcggggcttt agccgctgct caaggagcgc
   255481 attcacgggc ctatccggca tatcgtggat gtctttgcga tctgcgggac cttgttcggg
   255541 cttgcgacct cgctctgatc cggtgtcctt cagataactt cgggcccgaa ctacctgctg
   255601 ggcgtccccc aatcgatata tgtccagctt ctgctcgtca ccaccgtcac ggcaatagcg
   255661 actatctcgg tcgttaccgg cgtcgacaag ggcgtccgca ttctcagcga ggtgaacctc
   255721 tttctcgcgg tgatgctgat gattttcgtg ctcgtggtcg ggccgaccgc tacgctgatg
   255781 cgagatctcg tccagaatat cggcctctat ctcgacagcc tgctcttgcg gacgttcaac
   255841 atctatgcct acgaaccgcg cccgtggatc gatactactg ggcctggtgg atttcctggt
   255901 cgcccttcgt cggcatgttc atcgcgcgga tatcccgcgg acgtactgtg agagagttcg
   255961 tcaccgccgt tctcttcgta ccggccattt tcacgttcct gtggatgacc gttttcggaa
   256021 acacggcgat ttacgtcgac acgacgatcg ccaacggcga gctggcatgt gccgtgaagg
   256081 cggacctatc gatcgccctt tttcagttct tcgaatatct gccattgtcg gcggtgacct
   256141 cgacactcgc ggttctgctc gtcagcatat tcttcgtcac ctcctccgat tccggcgcct
   256201 tggtgatcga tacgatagcg gcgggcggca aaacggccac tcccgccctt cagcgggttt
   256261 tctggtgtgc cctcagcggc atcgtggccg ccgttctgtt gtccaccgga gggcttacgg
   256321 ccctgcaatc cgccaccatc tccacggcac tgccattcag cctggtgatg ctcgtacttg
   256381 tacggtcgct gttcgtcggg atgagggccg atcttgcccg cacacgctcg cccggttcag
   256441 tcgggcacgg gcctatcccg cgtccggcgt aacatggcaa cgccgcctgg cgatgacgct
   256501 cagcaccccg gacaagccgg ccgtggagtc gttcatgcag gcttccgtcc ttccgcccct
   256561 cgaagcggtg gccagggagc tgacgtaccg ctcgcggccg gcttccgttg cccgcgatgc
   256621 ccgaacggga acactgacgc tcacggcgcc tgcagaaagc caccgcgatt tcgtctatgg
   256681 ggttcagatg tccgaacaca agcttcccgc cttcaccgca ttggaggcga ccaacgccga
   256741 tgtgcgttac gaggcgcgaa ccttcttttc ggatggcagt cgcggctatg acatcatggg
   256801 aatgacggac ggccagatca tcaacgacgt tctgttccag ttcgaacgat acacaggctt
   256861 cgtgcggtct cccgaggcct cgctgttggc ggcctcaccc gaacagcaat agctccgcac
   256921 gaaagttgac cgccttcaga accggatgcg gaaaccgtat cggctttccg cctgcgcccg
   256981 cgcctacgtg caaatgcaca gatcagaaag gcgggacttc ccccgccttt cgtcagaacg
   257041 atatctgatt gcgttccaac gaaatcggaa cttgcaacca gcatcagcgc ggcgcgagac
   257101 gctccaggtc gccgagccgc ttcagcgcag cctgctgctg caacaggttg tagtttatgc
   257161 cgctggcgtt gagcgtgctg ccgggctggt aggggtactg gtcaaaatcc tggaagaact
   257221 ccttgatctt gctctggatc ggcaccagga gccacatgtt tcgggctatg aactccatgg
   257281 cccctccgcc ttctttcgtc ccccgttcat aagggtccat tctcagattg gcgatattgg
   257341 cccaactcgg cgtctcgcgc gtggcggtgg cgatgttgcc ttcgctgttg actgcgaagc
   257401 tgagcttcca gtcattccac cttatggcat tcagattgcc gccctggtcg aagtagtaga
   257461 ctgcttcgcg aggcggctcc tcggcctcac ccttaaggag cgcggtcaag tcataaccgt
   257521 cgagatggac cttgaaggtc ttgtcgccgg acttgaagcc cgtcttcatc tcctccttga
   257581 catcagggat tccggcggcg gtggcgaagg tcggcatcca gtccatcagc gtcacggggt
   257641 cgttgatttg cgtgcccggc ttcaccacgc cgggccagcg caccatcatg ggaatgcgga
   257701 agccaccttc ccacgtcgtt cccttttcgc catggaacat ggtcatcgcg ccatccggcc
   257761 acaaagcgag ctcggcaccg ttgtcggtcg tgtagagcac gatcgtgttt tccgtgatgc
   257821 cgaggtcgtc gagctgctgc agcagctgac cgacatggcc gtcatgctcc accatgccgt
   257881 cggcgtggat gcccttaccg gtcttgccca tggattccgg cttcaggtgg gtaaacacgt
   257941 gcatgcgtgt cgagttgaac cagcagaaga acggcttgtc ggccttcgct tggcgatcga
   258001 taaaatcctt cgctgccgcg aggaactctt cgtcgaccgt ctccatccgt ttggtgttga
   258061 gcgctccggt atcctcgatc tttccgtccg cgctggactt gatcacgccg cgcggcccga
   258121 aattcttccg gaattcctcg tccttcggat agaagtagcc ttccggctcc tcttcggcat
   258181 tcaggtggta gaggttgccg aagaactcgt cgaagccatg gttcgtcggc aggtgctcgt
   258241 cgcggtcgcc caggtgattc ttgccgaact ggccggttgc atatcccttc gacttcatga
   258301 cgtcggcgat ggtcggcatc cagtcctgaa tgccgtgcgg atcgccgggc atgccgatcg
   258361 tcagcagccc cgtgcggaac ggctcctggc cgagtatgaa ggaagcgcgc cctgcggtgc
   258421 agctctgctg gccataggca tcggtgaaga tcgcgccctc ggcggcgata cgatcgatgt
   258481 tcggcgtgcg atagcccatc aggcccatgg tgtaggcgct gatttgcgga atgccgatgt
   258541 cgtcgccgaa gatgaccagg atgttcggag tcttgccgct acctgccgaa gattgctcct
   258601 gagccttcgc gctgccgacg gccacggctc cgttcgctgc agcggcagcc gcaaggatgg
   258661 tgcctcccag caaaaggctt cggcggtcta tggagattga accctgcgca tttttgcgct
   258721 tgtcagcatc tggaaagctc atgccttgct cctcttatac gttccaactc gcgcggcttc
   258781 tgccggtttg gagttctgag atttcataga agcagcgctt ctgcagaccg gttccaaact
   258841 cgcgtttcgc agccggctcc tgccccatcg ggttgattga gagaagcacc cgccctgatg
   258901 agagcccctc ggattatccg ccgaagtgcg ggtcgagaga agttggacca aggggaaaca
   258961 taaccaggcg acggccgctg gcagagagct gccggtcttg ggcgcaatta cggcgcgttt
   259021 cgcgtttcct tgaaacccgt tcgattcagg agtaaaattt cggcagcaat tcaaagcgtt
   259081 acagacacgt gcgatctgaa gcggacggaa ttgcgtaagc tgcacgcggg taatgacgct
   259141 ttgtcaggct tcataggtgg aggttgtcat gcccaacact ctgatggcag gaaaaagaag
   259201 ccaggattgg gcgaatctgg tcctggcggc gtgcctgttc gtttctccct gggtcatcgg
   259261 ctttgcggcc gattcagtgc cgacctggaa tgcatggatc gccggcatcg tgctcggcgc
   259321 ccttgcggtc gcgacccttt cggctttcgc cgaatgggag gaatgggcca atatggtgat
   259381 cggcctgtgg ctcatcgttt ctccctggct gcttggcttc acgggaaatg tgaatgcgat
   259441 gtggacccat gtcattctcg gcgtgctcgt tgccgcaatc gcggcctggg cggtctggga
   259501 tttccggcac cactcgcacg cctgatgcat tttcccgaag gccgagcgct tcggaataga
   259561 ggactcggaa acaggaaacg cgccgtatct ctcagatgcg gcgcgccttg gagcgggatg
   259621 agtgcgcggt ttcgcgcccg catcccgccc tactgcatgt ttccttaatc ggatccgatt
   259681 gaaggacaaa aacatgcagc agatcaaagt gctacagcga tctttgtggg tctgataaga
   259741 cgcgcggcgc gctgtaatgt atgccgcgtc gcattatccc accgcgcgct cctgcacgac
   259801 cgcgtcgatg tcaggaacac cgagttcgcg gcgttcacgt tcggtctcta tggcgagatc
   259861 cagcaccttc tgcaggtcag cggcatggcg gaaacccggc tcgacggttc ggccggcctt
   259921 caccgcctcg acgaagcgct ggtagttggt cggcacggtg ccggcatcga ctgtcctcca
   259981 cactgccttt tcaacgtcgg cgcccaggca ggcgcgcagg ctcgaaccgt ccggcgtatg
   260041 aatgacctcc agcgcacctt tgtccccgtg caacctgagc ctcagctcgt tcagatggcc
   260101 tgtcgcccaa cggctcgcgt ggatcaccgc catcgcaccg ttttcaaatt cggccgtcat
   260161 ggcaaagctg tcattggcat cgagatcgta ttcgcctaac cggttgcccg gggctttgtc
   260221 gaaggccttc aggcgcgcaa agaccctttc gaccgagctg tttgccccat agccggcaaa
   260281 gtcgagaatg tgtatgccga catcgccgag cacgccattc gagccatgtt tcgtggagag
   260341 gcgccacagc catttggact cgctcgccca gtcgccccaa gccttcgaca ccagccagct
   260401 ttggagatag gaggcttcga gatggcgcac caggccgatt tcgccggcga cgaccagttc
   260461 gcgcgccttc tgcagcggtg cgacattgcg gtaggtgaga ttgaccatgg tgacgaggcc
   260521 ggcgcgctcg gccgcggccg ccatctcggc ggccttctcg taattttcgg ccagcggctt
   260581 ttcgcaaagc acatgcttgc cggctgcgat gagggcaagc gtcgtggggt gatgggcctt
   260641 gtcgggcgtc acgttcgtcg ccgcatcgaa ctctccccag gcaatcgcct cgtcgaggga
   260701 tgtgaaagta cgttcgatgc cgtgcgtgga agcgaaggcc cgggcacggg acgggtcgac
   260761 gtcgactgcg ccgaccattt cgacgccttc gatctcagca aaggctttcg catgactgtt
   260821 ggccatgccg ccggttccga gaataagcaa acgcatggga gaccccttta ccgatatccg
   260881 gcttcgccgg ccttgtgcag tctcgggccg cgctcgacga tcggctccag cgccttctcc
   260941 accgggacgt tgggtgcgtc gtggatggcc ttatacgtgc cctgcgggtt gtatgcccat
   261001 ttcaccgcgt tccgcagcac cttgtgcacg gtcgcatcgt gataggtggg ataggtttca
   261061 tgtccggggc ggaaatagaa gatattgccc gcgccgcgcc gccaggtcag ccctgagcga
   261121 aatacctcgc cgccggcaaa ccaggagatg aagaccgtct ccaacggctc cggcaccgag
   261181 aattgctcgc catacatttc ttcattctcg atcacgaagt tttcgcccag gccctcggca
   261241 atcgggtgtc gcgggttgac gacccagacg cgctcgcgct ctcccgcctc acgccatttc
   261301 agcgcgcatg gcgtgcccat cagccgcttg aaaaccttgg agaagtggcc ggaatgaaga
   261361 acgatgaggc ccattccctc ccaaacgcgt ttggctacgc gctcgacgat agcgtcgtcg
   261421 accgccccat gatccttgtg gccccaccac aggagaacat cggctgcggc aagccgcgcc
   261481 tcgctcagcc cgtgctcggg ctcctgcaat gtcgccgtcg tcgcattgat ccccgggtcg
   261541 gaattgagcg cggcggcgat cgtgttgtgc atgccctcgg gatagatctc ccgaaccacc
   261601 gcattcgtct gctcgtggat attctcaccc cacacgatgg cattgataga caagttcatt
   261661 ctcctcgtgg tttggggcac ccgctgccgg atgccagctg tccgtgattt gagtctgcgg
   261721 gcacggagcc gggccgggta aaccccacgg ggacccgcca tttcctgccc taacgtttga
   261781 ggcttgggaa tgatccgaaa tcctccggac cagacatagc ttctaggctt tcgcgggccg
   261841 atcaatctgc ggcccgagtg tattcacatg gctccaatct gaagcgtgct gcactcaatc
   261901 gaactcatac gacgcgcttt aggtcttcca tgcatgtctt tatcccaaaa ccgtgcgcag
   261961 ttttgggcga cacgcaatta tgaaactcgt caggccgcac cccgcatttc gatccgtccg
   262021 gtcgcccggc cgcctgcatc gaagcgatga acctgcccgg cggcagggga tatcgtgatc
   262081 cgctctccgg gctggtgctt cgcaatcccg ctctcgcgga cgatcaccgg ttcgccagcg
   262141 cctatgtcga gatagatata gctgtcggag ccgagcattt ccgaatggat cacggtgccg
   262201 ctccactcac ctctctctcc atcgatttca agatgctccg cgcggacgcc gatcgtgtct
   262261 gccttgtacg gctccgcgaa ggcacccgac aggaagttca ttttcggcga accgataaaa
   262321 ccggcgacga agaccgagtt cggcgtctcg tagagctcca gcggcgtgcc tatctgctct
   262381 acgagaccgt ccctcaggac acagatccgg tcggcgagcg tcattgcttc gacctggtcg
   262441 tgggtaacat agatcatcgt cgtcttgtgc atgctgcggt gaagcttggc gatttcgagt
   262501 cgggtggcga cacgcagcgc cgcgtcgaga tttgaaagcg gctcgtcgaa aagaaagacc
   262561 ttcgggtctc gtacgatcgc ccggccgatc gccacgcgct gcctctgccc acccgagagc
   262621 tgccgcggca gtcgctcgag atagggcgtc agctgcagca tttccgccgc ggtctcgacc
   262681 cgtttgcggc actgctgctt atctttgccg gcaagctgca tgccaaatgc catgttctcg
   262741 taaaccgtca tatgcgggta gagcgcatag gactggaaca ccatggcaat gccgcggcgc
   262801 gatggcgtca gttggttgac gatctgacca tcgaaagaga gagttccgga ggtgatttcc
   262861 tcaagccccg cgatcagtct caagagcgtg gacttgccgc agccggaagg gccgacgaag
   262921 accatgaact cgcccgactt gatgtccatg ctgacgccct tgatcacatc gaaggcgccg
   262981 aaggacttgc ggatatcgcg caattgaagc tctgccatct tattctccta tcctttgacg
   263041 ccgcctgcgg tgaggccgga aatgatccgc cgctgaaaga tgagcacgag caccacgagg
   263101 ggcaccgtga cgatcacgga cgctgccatg atgttgcccc agggaatctc gaactggctg
   263161 cccccggaga gcagcgcaat cgcaaccggc acggtgcgct gcgtgttgga cgacgtgaat
   263221 gtcagcgcaa agaggaactc gttccacgcc gcaatgaagg cgagaaggcc ggtcgtcacc
   263281 agcgccggcc acatcagtgg catgaagacg cgcgtgatca ccacccaggg agaagcgccg
   263341 tcgacgattg ccgcctcctc gatctcgatc ggcaggtccc gcatgaaggt agtcagcacc
   263401 cagaccgtga agggcagtgt gaagatcatg taggaaaata tgagcgcaag cggcgtgttg
   263461 aagatcccga cgaagcggat gagttcgaag aggcctgcaa gcacggcgat ctgcgggaac
   263521 atggaaacgg acaggatcgt cagcaaaagc agcccccggc cgcggaagcg cacccgggca
   263581 agcgcatagg ccgcggtaac ggcgagaagg agcgatatgg cgaccacgag cgtggcgacg
   263641 aggagcgaat tgccgagatt gcgcacgaat gtgccgtgcg aaaagatgtc ggcatagttc
   263701 gcgagcgaga aatcggtcgg ccagtagtcg atgcgaaaca gcgccgtgcc ggacttcaag
   263761 ctcgtcagga tcgcgtagta gaatggaaag acggcaatca ggatgatgac ggcaacgagc
   263821 gcgtagaacg cggtccgttt tacaagcgta acgaccatca gcgttctcct ccgctcagat
   263881 tgaggcggcc gagccacatg tacaggatcg tgatcgtggc gatgatcagg aacaacatgg
   263941 tcgaggccgc cgcgccgtag gcgaacttgt cgaaatcgaa gaggttttcg cgggccatga
   264001 ccgacatggt cttcgtctgc gcgttgttcg gcgtcagaac gtagataagg tcgaaaatgc
   264061 gcagcgcgtc gagcatgcgg aagatgaccg caaccatcag cgccgggcgg atcagcggca
   264121 gggtaacccg ccagaacacg cgcactggat gcacgccatc gattttcgcg gcctcgtaga
   264181 tatcgcccgg caccatttgc agcccggcca ggatcaggag cgccataaag ggggtcgtct
   264241 tccagacgtc cacgatcagc acggcgatca tggcggtatc ggggcttgcg gtccaggcga
   264301 tcttctcgcc gatcaggccg agaccgagca gcatgtcgtt gaggatgccg aactgatcgt
   264361 tgagcatcca tgcccacatt ttggctgaca cgatcgtcgg gatagcccag ggaataagaa
   264421 tcgccgcccg gacaagtccg cggcctggga actgtgcgtt gagaaccagg gcaacgatga
   264481 gacccagcgc cgtttcgatg ctgacggaaa gaaccgtgaa cttgagcgtg ttccagaccg
   264541 cattccacca ggcgggatcc gcgagcagac ccctgtaaat ggtgcgaccg ctcttcaggg
   264601 tgatccatga gaaataattg gcgaaaccga cgaattcggc atccgacagg ttggtcagcg
   264661 aggcattcgt gaaactgaag tagatggttc tgatgagcgg ccagccggcc acgagcgcca
   264721 gaacgagaaa agtaggcgcg agaaacagcc aggccgaacg gacacgttgc gcctgcaggt
   264781 ccgagcctat cctggcgcca tgcgcaagcg cagccggccg atcggcgagc gagagatcag
   264841 tcatgacgtg aacctaccga ttggcgcagg ccctcgcccg cgccgttgac cttggcccgg
   264901 atggcagggt gccatccggg cgctgcggat tcttaccagg agtcaccctt gagttcggtc
   264961 agttcgactt cgagaagttc caggttctcc gcggccgttc cgttgcccga aagcgtgttg
   265021 tgcacggcgc tccagaactt ggacgaaacc tcgttatact tcaccttggc cactgccgag
   265081 gggcgcggca cggcgctctc gaagataggc ttccagtgcg gcatgaacgg ctgagcggcc
   265141 gcgatttccg gatcatcgta aagtgcagcg atcgtcggca ggttcgagag ctcgatcgcg
   265201 cgcaccttct gcgtctcggc tgacccgagg aatttgacaa acgcaatcgc cgcctcctgc
   265261 tcgtcggaat atttcgagac cgcgagattc catccaccga gggtggaaga tggcttctcg
   265321 ccatcggcgg cggccggcaa cggggccact tcgaatttgc ccttgacggc actgtcgtcg
   265381 ccgttaccga gcgcataggc atagggccag ttacgcatga agaccgcatt gccggtctgc
   265441 cagaccccgc gcgattcctc ttcctgatag gcaagcacgc ccttgggcgc gatcgtgccg
   265501 atccattcct tgacacgttc cacggccgcg gccgccttct cattattgac ggagatcgtg
   265561 ccatcgggct cgacgatctg gccaccgccc gaggacttga tccactcgag tgcgttgcag
   265621 gtgagccctt cataggcatt gccctggaaa acgaagcccc agatatcggc attgccggca
   265681 gcacgctcct tttcctgaat ttccttggcc gtcgctgcca tttcatccca ggtcttcggc
   265741 ggcgccttgc cgtatttgtc gagcaggtcc ttgcggtaat agagcgccgg cgcatcggta
   265801 tagaagggca aggccaccaa cttgccgttg acggtctgtg actgaatgat cgaggggaaa
   265861 tggtcggcga cgacgtcctt cgtggcctcg gtcaggtcta cgaactgctc ggcgagctgt
   265921 ggagcccaga tgacatccgt ctggtagacg tcgacgtcct tgttgccggc cgcgagccag
   265981 agccggtatt ggctgaactg ctcgctgctc gacgccggca tcgtcaccag attgacctta
   266041 tggcccgtct ccttctcgaa cctggcgatc tgctcgcgca gaaagctcag attcttaccg
   266101 gtcgaattgg ccgccatcga caattcggtg gcggcagcaa catcgattgc accgacgata
   266161 gcggcacagg aaatcagcgt cctgataaaa ggcttcacgt ccattggtcc ctccaaaact
   266221 cccctccggt ttcgcatgct cctcgaaaaa atcgaaaacg gtttgggtgc gcagaagctg
   266281 tcagaaccca aatggactgt caagatacgg ttgcatcgga agtaatcgga atagccatct
   266341 cgaacttttc tatttatatt ccagtagtta tactcaaagc cgtcgcactt gatcggcaac
   266401 cggtttcgct cggcaaggcg acttggaaaa agtcatccac aggaatttaa aacgatttgg
   266461 ttcatgatgc cagctatccc gatcgcgccc cgcccggtcc gccgaagcga tgcatggatt
   266521 gtggccgtcg gcgaacccgc tatagttccg cgctggtgtc cgcagcgctg cgcatcgact
   266581 cgatgccaaa ggaagggcgt atgcggcatc tcggattgct gcgtgacttg cttcggaagc
   266641 aacgccgggc gacgcgcaga aggggcccag ggaaagaaca gtgaaactca aggaattcgc
   266701 caaacagttg gggctctctc caacgacggt aagccgtgct ctgagcggct atccggaagt
   266761 cagcgagaag acccgtaagc gcgttgccga ggaggccgtg cggctgggat accggccgaa
   266821 tatcaacgcg gtgcgcctcg tcacgggccg cgccggggcg atcggcgtcg tgatgggccg
   266881 caacgaattc cagttctgcg aattcatgag cggcatggcc gaacggctgg acagcgagga
   266941 tatcgacatt ctcgtgagcc ccgttgcggt tcaggacacg aaagccgaga tccagctcta
   267001 tagccgcctg gcgaccagcg gacgggttga cgccgtcatc gtccattcgc cgaaaccgaa
   267061 cgacgagcga atcctgctgc tccacaagct cggcattccc tttctggtgc atggccgttc
   267121 ggagaccaat gtgccgcatg cctggctcga tatcgataat gaaggcgcca tacgccgcgc
   267181 cacctcgcat ctgctcgatc tcggacacag acgcatcgca ctgatcaacg gccgcgacgg
   267241 tctcaccttc acgcttcacc gggataaggg ctaccgtgag gcgttggagc agcgtgggat
   267301 tcccttcgat ccacgccttg tcgcacacgg ccagttcacc gacgagatcg gcttccgctt
   267361 cgcccgttcg ctcctcgagc aatccccccg tccgacagcc ttcgtcgccg gctcgatgat
   267421 gacggcactc ggtgtctacc gggccgtacg ttccttagac ctcgtcgtcg ggcgcgacat
   267481 ctcggtaatc gcccatgacg acgtctttcc ctacctcacg gccgacaaca tggccccgtc
   267541 tctctcgacc agccgttcgt ccctgcgcgc tgccggcgct cgcctcgccg acctaaccct
   267601 tcagctgctc gccggccggc cggcctcgga aattcacgaa ctctggcctg tcgaactcat
   267661 tttacgcgaa tcgacaggcc cggcggccga ggccgcgcag tagaccggag ctatgggtca
   267721 cagtggtcga gaggcggaag cggccggaaa atcgtgcaca cttttcctca tcctgctcca
   267781 ccctccatcg ccggggcatc ctcgcgaccg ttcagccgga acagcaggtc ttcgtggact
   267841 gccttgaggt ggaaaaccag gaaagcggac gcctcttcga aggcgcctgc ccggcaaagg
   267901 cggatcagct cggcatgttc ttccatcgcc cgggtcatcg ctgcgacgct cgatagctgg
   267961 acgcgcgtgt aacggtcgct cgtctgtagc agcgaggcga cgatctgctg cgttcgcggc
   268021 atgtcggcac gccggtacag taccatgtgc agttcggcat tgagctgacc gtatgaatca
   268081 atttcgcccg ccgtcgtggc tttaagaaag cggttctgag cctcgtccag gcgcgcaaaa
   268141 tcgtcgccgt cgagaagagg cgccgatttt cgcaggagcc gcggttcgag gagagcgcgc
   268201 agttcgaaga catcgtcgat ttcggcaagc gacagttcgg agacgatggc tcccttctgc
   268261 ggcacgatcc tgaccagacc ttcagcctcg agttgaaaga gaacctcgcg cacgggaatg
   268321 cggctgacgc cataggtttc agccagcgca tcctggcgca attgactgcc ggccgggtat
   268381 cggcccgaca ggatcgcctg ccgtatttcc tcgatgagtg cgcctgagag ggtgcgatgt
   268441 ttcagatgtg aggccatgaa cgctcgctac aggaagaccg tcagaaatga tattgactcg
   268501 cagaatgtat aaaatctact ttatacagaa accagggagc agtccatgaa ccagtcagtt
   268561 gagccgccgc tttatgcgcg cgccatcatc gcactctccg aagctttgct ctcgctcgag
   268621 aagctcgtag tcgccggcct gatgggcgtg cttctcgcac tcatcctgct caatgtcgtg
   268681 acccgctaca gcggacaccc gctctactgg gtcgatgaat cggccgtata tgccatggtt
   268741 tggctcgcct tcatcggagg ctcggcgctg acgcgcctca ggctcgattt ttccgtgacg
   268801 ctgctgacgg attacctgcc gcctgctgct gcgcgctgga tgagggcggg ttcgacactg
   268861 ctcgtcctcc tgtttgcact ggcgctcgca gccttctgct ggctgtggat ggacccggtc
   268921 ggaattttcc gcgccggctt cgatacgaaa gctttcgccg ccgagagctt caatttcctc
   268981 tataccgagc gcagccagac gctgaactgg cctatctggg cgatcagcct cgtcatcccc
   269041 ctcttcgccg tcaccatgac ggttcactgc gccgccaatc tcgtcgaaga cctcggtctg
   269101 tcgccgcagc aaaagcgacg cgaactctcc agcgccgagg gagtgaactg atgctcacca
   269161 ccgccgcctt ccttgccttc atgctcgtcg gcgttccgat aggggtctgc ctttgcctcg
   269221 gcagcatcgt ctacattttg gcatctggga atcccctgct cttccagagc tttccgacgc
   269281 aacttttcgg cggcgtcgac aattacggcc tgatttccat tccgctcttc gtgctgatcg
   269341 gcgagatcat gaacggtggc ggaatcacgc gccgtataat cgacatgacc atggcttttg
   269401 tcggcgccat gcgcggcggc ctcgcctatg tcaacctgct ggcgaacatg ttcgttgcct
   269461 ccattctcgg ttcggcgacg gcgcaggtcg cggtcatggc gcagatgatg gtgccggaga
   269521 tggaaaagaa gggctatgac aagaccttcg ccgccggaat tacggcctat gcgggcatgc
   269581 tcggccccat cattcccccg tccatcatgt tcgtcgtcta cagcgtgctg gcgcaggttc
   269641 cggtcagcga tatgctggcc gccggaattg tgcccggcgt cctgctgacg gtagcattct
   269701 gcctcgtcat cgcggcgatg ggactcgtct acaactatcc gcgcggcgaa cgtatgaagc
   269761 tcaaggatcg tgtccggatc gtgctggacg cgttgccgac gcttctcata cccttcgtca
   269821 tcgtcggctc cgttctgtcc ggccttgcca atgcgacgga ggccgctgcg gtcggagcgg
   269881 tcgcagcagt gctcgtcggc cgcttctgga tcggcgaact cagattcgcc gaccttccgc
   269941 ggatgatgct gcgggccggc atctactcgg cggtggtcct cttcctcgtg gcggcggccg
   270001 cggtcttttc ctgggtactc gtctacggaa tggtgccgca gcaggtagcc ggctgggtcc
   270061 agaccgtcgc atcggatccg gtcaccttca tgctgctcgt caatatcatc ctgctcatca
   270121 tcggcacggt gatcgacggc gcgcccggtc tcatcatgac ggtgcccatc ctcctgccga
   270181 tcgccaccga ggtttacggc atcgacccca tccatttcgg cgtcgtcgtc gtcgtcaacc
   270241 tcgttctcgg cttcctctcg ccgcccgtcg gactttgctt cttcgtcgcc gcagcggtca
   270301 ccggtgccaa gcccggcaag atgttcctgg tcacactgcc gttcttcttc gtttcctgcc
   270361 taatgctcgt gcttctctcg ctcattccgt cactttccac cttcttcgtc cggtaaatca
   270421 aaacgaacca accagaggat cttccatgac agtttcccgc agaactttcc ttggcggcat
   270481 cgccgccggc acagcactct cgctcgctac gccatcgctc gttcgcgcac aggaaacgcg
   270541 tacgcttcgc cttggtatcg tcacgccgcc cgggcacccg tggaacaacg ccgctctcaa
   270601 ggtgggtgaa ggtctcaagg ctgaaacgaa cggccgcctt tcgctctcgg tcttccccgc
   270661 cggccagctc ggaaacgaag cggccatgct gcagcagatg cagagcggcg cgctcgatct
   270721 cggctggatc atgaccgccg aactcggctc gcgcattccg gcgatcgccg cgatcaacgc
   270781 gccctgggtg gtggattcga ccgccaaggt cgcaaaactc gtacgcgagc cgctcgctat
   270841 gaagctcctc gatgttctgc cggccgagac cggcacggtc ggccttgcat ggggcataac
   270901 caccatgcgc gtcgtcttct cggccaggga gatcgccggc cttgacgaca tcaacggtat
   270961 gaagttgcgc atcaatacga cgccggccta ccgggatttc taccagctcc tcggcgccgc
   271021 accgacgccc atcccgacac ctgcggtttt cgacgctatg tcgaacggcc aggtggacgg
   271081 tctggaggcg gacctcgact tctcctggaa ccagcgcttc gacaaggttt cgaagaccat
   271141 gctgaagatg aatgccatct tcatgccctg cgtcgcgctt gcctcgggcc gcgcctggca
   271201 gaccctttcc gccgccgacc gcgaaatcat cacgcgtctc accaaggcag cccttgatga
   271261 acagatcgat gcaacggtcg ccaacgagcc ggcgctcctc gaaaaatttg ccggggcagg
   271321 cattccgatc aaggatatca ccgtcgccga cgccagccgc atcatcgctg aatacgacaa
   271381 gatctggctg ccgaaggcac cggttctcgc cgagttgcgc aaagtcggcg caaccctctg
   271441 acttttcgat cagttcagcg ccagccggct acggctctcc gtggccggct gtattttatc
   271501 tgcttgcacc ttatcgtcgc acgcgccaag agtgcccgtg atcaagagtg cccgtgatca
   271561 ttggacgtag cggatgcaga gtagtgaaat tgcgattatc ggcggcggcc ccgccggcct
   271621 gatggcggcg gaaatcctgt cacgctccgg ccacgcggtg acgatctacg aggcgatgcc
   271681 gagcgcggcg cgcaaattcc tgctcgcggg caagtccggc ctcaacatca cgcactccga
   271741 acacagcaag gcttttatgc agcggttcgc cgatgcgtcc gcaaggctgc aaccggcgct
   271801 cgacgctttt gctccgaaag acgttcgcgc ctgggcggat gaacttggcg cggaaacgtt
   271861 tgtcggctcc tccgggcgcg tctttccgag agccatgaag gcttcgccgc tgctgcgcgc
   271921 atggcttcgg cggctggagg cgcaaggcgt ccggctcctc acccgccatc gctggtcggg
   271981 ctttgccgag gacggttatg ttttcgacac gccggagggc aggacgctcg tgcgttgcga
   272041 cgcggctctc atggcgctcg gcggcgcgag ttggccccgg ctcggatccg acgctgcctg
   272101 ggtgcccccg ctgcgggcaa gaggcgtacc gatcagggat ctccgccccg ccaattgcgg
   272161 gttcgacgtc gcatggagcg gggccttccg tgagcgtttt gccggtcagg cgctgaaagc
   272221 agttaccgcc acatccggcg ccgggaccat cccgggtgaa ttcgtgatga gccgccacgg
   272281 catcgaaggc agcctcgtct atgcccacgc ggcttgcctg cgcgaccggc tggagcagga
   272341 cggaaaagcc tccctcatgc tcgaccttgc gccaggcaga acggccgaaa ggctcgcgcg
   272401 ggatctcgcc cggcaggatc gcaaggcgag cctctccaac cgcctgcgta agggcgccgg
   272461 gctcgacggt gtgaaggcgg cattgctgcg cgagctctcg caggaggcaa ccaggatagc
   272521 tccggagcaa cttgctgcac ttatcaaggc cttgcccgtt ccagtgcttg cggcgcggcc
   272581 gatcgcggag gcgatctcgt cggccggcgg tgtccgcctg gacggcgtcg atgaacgcta
   272641 tatggtgaag gccgtacccg gcctcttcgt cgccggcgag atgctcgact gggaagcgcc
   272701 aacgggcggc tatctcctta cagcttgctt tgccacgggt cgcgcggccg cgcggggcgt
   272761 gaaggcatgg ctggacgccc gtccgtgacg ctgccggtca gttctcagct tttcggcctg
   272821 atggagaaca tggcaccggc tgccaaaatg aagagcccta tgatcgcgag ttgaagggtg
   272881 cttgggatgc cgacgaggat cagcacgttg ttgacgagcg tgattagcaa cacgccgagc
   272941 aacgttccaa gcaccgtacc cgagcccccg gttatgcgcg cgccaccgag gatgaccgca
   273001 gcgatgacgt ccagttccga ccccgccaga tcgaacggat ttgcgaggcg attgctcgaa
   273061 acgtgcatga tgccagcaat tccagccagt aggcctgcat aggcgaagac gaacacatgc
   273121 acggtgcgca gattgtatcc gagccgcgag gcgatgccgg cgtttccccc caccgcatag
   273181 agcgcccgac cgatcagggt gcggttgagg atgtaccagg tgacggatgc ggcgacgacc
   273241 agaacgagga aataggccgg caatgtcgca accgcaccat tcgctccttc atatcgcaga
   273301 agcgcaagct tcccgaacgc gtccatggac tcgggaatgt tcatgaacag cgcggttccg
   273361 atgaacgtca gcaggaagcc gcggatcgca tattgcgtgc cgatcgtcac gatcagcgaa
   273421 ggcgcctgca atgcgtggac cagcaagccg ttgcagatgc cgaggatggc gccgctggcg
   273481 gcggcgatgc cgagaatggg ccagatggac agatccggcg cgtaattcgt gaccagcatg
   273541 gtgatcacat acatcacgag tgcggcaatg gcggtaaagg acacatcgag cccgccggat
   273601 gccagaacca cgagaacgcc aagcgcgaaa aggccgcgca ccacggtgga gcgcgccata
   273661 tcgaacaggt tggacacctg ccagaacccg ggattgatcg tgcccacgac gatgcagagg
   273721 atgacgacca gaaggaaggt gacggccgga ggatggcgga tgaaccagcg catgatccgg
   273781 attgcggcgg ggacatcccg cattcccgcg acggtcgctg cggcattggc catgttattg
   273841 aactccttgg ccggcttcgg ccatcatcga tttgtagatt acgtcttcct caagcccttc
   273901 agccgtgaag acatcggcga cccggccctt gcgcatgacc atgacgcgat cgcagttctg
   273961 taggagctcg ggcaggtcgt cgctgatgat aatgacgctc atcccatctc cggcaagacg
   274021 ctggatgatg cgaaaaatcg tgtccttcga cccgacatcg acaccgacgg tcgggccgtg
   274081 caggatgagc aggctcggct cgatggtcag ccagcggccg atcagaaccc tctgctggtt
   274141 gccccccgag agagacgtga cgggattgtc gatatccggc gtcgcgacct gcagatcgtc
   274201 gacggtcttc tgcgccagtg ccctcgcccg gcggctgtcc agcagaccga atgcgccccg
   274261 gagccggtcg aggaccgcca tgacgatgtt ttcgcggatg gattttccaa gaaaaagccc
   274321 ttccgacagg cgatcctccg ggacatagcc gatgccggcc gcaattgccg aggccggaga
   274381 agacaggtct gccgctttgc cgcccatcag gacggagccg cgccgcgccg gttctacgcc
   274441 ggccagcgaa agcgcaagct cgttccgccc ggaatccagc agtcccgtga tcccgaatat
   274501 ctcgcccttg gcaaccgcga agctgacatt gtcgaagccg ctccccccga gttgctcgac
   274561 cgaaagcagc gtctcgtccc cgtgcgcgtc gacgcgataa cgcgtctcgt ccaacttctt
   274621 gcccgtcatc cagaagccaa gttcgctctt cgattgggtg gaaacgtcgc attcggcgac
   274681 cttgaggccg tcgcgcatga tgattgcctg cccaccgatg gccttgcact cgtcgagctt
   274741 gtgcgtcacg aaaaggaccg acacgccttt ggcatgcagg ccgtgaacga cgcgaatgag
   274801 gttatcaact tcgcgccgcg tcaatgcggt cgtcggctca tccataatga ccagaccggc
   274861 atcggaagcg atagcgcgag caatggcaat gagctgacgc gtcgcgatgg gtagttcttc
   274921 gaccggcgtc gaaagaaagg cgggctccgt cggcaggccg acctccttca gcgcacggat
   274981 cgacgtttcc cgcagaacct tgagatcgag acgacgcgca agcctgccgt tggaggcgac
   275041 cagctgctga gtcagcgcga cgttttcctc tacactcaga ttgggaagaa gcgacaaatc
   275101 ctgataaacc gtctcgattc ctgccgccaa ggcgccgatc ggcgtcaggc cttcggtttt
   275161 cttgccattg atcgcaagct caccgccatc ggccggctgg gcgcccgaga tgatcttgat
   275221 gagcgtgctc tttccgcatc cattctcgcc catgagatgg taggtacggc cgcgttctat
   275281 cgtgaagctc acgcccttga gagcgcgaac gccgccgaag cgcttctcga ggttgcgaac
   275341 ttccaggaag ggcgtcccac cgccctgcgc ctcgacagag ggcatctttt gctcggcaat
   275401 gatagtcgac tgcattggca tgatccggag ttacggtctg tcgccggcag ggccatccct
   275461 gccggcggaa gcggctgcag ccgcggatcc gttcgacgtg tgatcagaac ggatactggc
   275521 tgtagttgga cttatcgacg tcaacccagg cttcgccgac gacgatgatg ccttcgccgg
   275581 gaccctgctt cacggacacc ttgttgtagc ccgggactcc gagatccata ccatcggtga
   275641 tttccttgcc ctcgatcacg agctgagcaa ccttgttcat cacataaccc gcatccttcg
   275701 ggtcccagaa ggaaatgctc tggaccgcac cggattcgag gtacttggcg gtgtccttcg
   275761 gcagcccgag gccgacgacg caaaccttcc ccacaaggcc ggcttcctcg acggcgcggc
   275821 cgattccgat gacgtcaatg gccgaaccgc cctggaagcc tttgatgtca ggatacttgc
   275881 gaaggatctc gcgcgccttt tcgtaggcct tgttggcgtc gttgaaggac tcgttcttct
   275941 cggagacgag ttccatttcc ggatatttct tggcgttctc cgcgccgccg tcagcccatt
   276001 gtacgtgcgt caggctgccg agcgacccga cgaatgacgt ccacttgccg gacttgccca
   276061 tgcactcggc cagtttctcg ttgaagcgcg cgccgaagac cttgttgtcg aaggcttcga
   276121 tatcgacctg cgtattcttc aagctgtcgg cttcgtgcgt gacgatcttg atgccgcggt
   276181 tcatcgcgcg cttgaagacg ccttcgagag cagaggggtc catcggcacg acagcgatgg
   276241 cgctgacatt cttcgcgacg aggtcttcta tgaggcgcag ctgctgggcg gcgtccgcct
   276301 tggcgggacc gatctggctc gtcgaaacgc ccgtattgtc cttgccgtag gcaacaacgc
   276361 cttcctccat gcgcgtgaac cagttttcgc cggtcacctt gacgaccgtc acgaccgggg
   276421 gcgcatcctg cgcgacggca atctgggcag cgcaaagcgc acccaaagcg accgtgcagg
   276481 tagcaatctt cttgtagaca gacatgagtg tctcctcatc acttgttgtt tgcccgacca
   276541 aaaactgacg gcggggggca ttgcgccgat cttgggacct cgcgatcaac gacgaggcga
   276601 aataaatgcg cgcagatcga cacgcgacgt cgccaggaac acgatcagga gcaggcccca
   276661 ggcgcagtcg cggaagaaat tcgagatatc gaggaaattg aacaggctcg acagcatctg
   276721 gagtgccgta gcggaaagga cgacgcagac cgtccgcccg tatccgccat cggggcgcac
   276781 acctgccatg acgacgatca gaatggcgat gaggacgtag gagctgccat agtcccattt
   276841 cacgcttgat gtgcgcgcgg cgatgatgat cccggcgacg gaagcaagca ccccgcagac
   276901 ggtataggtc agaagaagta tccggcgctg ggggatgccg gcgtaacgtg cagccttggc
   276961 attgctgccc atcagataga gcttgaaacc gaagggcgtg taacgcagca ccacgccgat
   277021 cagaaccgcg atggcgacga agagcgtgaa gcacatcggc aagccgagca ccggggtgtt
   277081 gccgaaattg tcgagcggct cgatgtaacc gagcgtgatc gccgagccgt ttgtgaacgc
   277141 gacggcgagt cccgtgaaaa acagctgtgt gccaagcgtg gcgataatcg gcgtaagccc
   277201 tgcaaacgcg atcaatgcgc cattcagcat gccgccggcg agaccgatca gcagtgcaat
   277261 caacgcaaat agccacgaaa aggcgagagg gacttcgtcg actgaaaccc agtcgcgcat
   277321 cagcaggtag gaacccacgc cggcgaggtt ggcgagagca atgcccgaaa gatcgatgcc
   277381 gccgtttccc gcaatcatgg cgagcatcac gccgagagcc agcagggcaa gctccggcac
   277441 ctgcgcggac atcgactgga aattgtagag gctgagaaag gtgtcaccgg cgaaaacgac
   277501 cgccagcgcg accaccagga cattggtcgc cacaaggaag ttgaattgcc ggtcggcgaa
   277561 cacgctcttc atatcagcct ctccaaaccc attaccggga cactcagcgc cccaccggct
   277621 taagccgctc ctgaccgcac gctttcaccc gcccaaagga gcacggccga caagccccgg
   277681 aaaacataga ggaatcgcgg tcagtaaccg ccttctccct ccgaaatttt tgggcaatct
   277741 atcgtgaatg ttgacatttg tcgagccatg tttgaattat gtagaaaatt gacgctctgg
   277801 agtgagcgaa tgcgcaccgg ggggacgttt ttgagtaagg ggccgccagc cgcagatccg
   277861 ggtctgcacc ggagacgtcg ttagattcaa cgtgctgttg cgctggcgca aatcgccagc
   277921 cacggacaaa agaggacttc catgcaaagg ttcatcaaca atccggacga ggtcgtcgaa
   277981 gacaccgtca agggcttcgt caaggcgcat gccgatatcg tccgcctcgg cgaaaatccc
   278041 cgcgtcatcg ttgccaagaa tgcaccggtc gccggcaagg tgggcgtcgt gacgggcggc
   278101 ggctccggcc acgagcctgc cttcatcggc tataccggga gaaacatgct ggacgcagtc
   278161 gccgtaggcg agctcttctc ttcgcctacg gccaagagct tccacgacgc catgcgcgaa
   278221 gcgaacggcg gcgagggcgt cgtctgcctc tacggcaatt acgccggcga caacatgaat
   278281 gtgaagatgg ccgtgaagct cgcggccaag gagggcatcg aaatcgcgac ggtggtcgcc
   278341 aatgacgacg tctgctctgc gccgcccgaa gagcgcgaaa aacgccgcgg cgttgcaggg
   278401 gaaatcttca tgtggaaaat cggcggggcc aaggcagcgg cgggagcacc cctcgaagag
   278461 gtccgtgcga ctgcccagaa ggcgatcgac aattgccgct cgatcggcgt cgggcttggt
   278521 ccctgcaccc ttcccgccgt cggccatccc aacttccgga tcgaaccggg cacgatggag
   278581 gtcggcatcg gccatcacgg cgagcctggc ctgcgcgtcg aggcgctgaa gaccgcggac
   278641 gaggtcgcca aggacatgtg caagatcgtg ttggatgatc atggcctgcc ggacggcacg
   278701 gaggtggcgg tgctcgtctc cggccttggg gcaacgccgc tcaacgagct ctacattctc
   278761 aacgatacga tcgagcgcga gatcagagcc cgtggcctaa aaatttaccg gacctatgtc
   278821 ggcaactact tcacctcgct cgaaatggtc ggggcgacac tgacggtgat ggcgctcgac
   278881 gacgaactca aggcgctcct cgatgtcgag gtccgctgca ccgctgtttt ctgaggaagt
   278941 gccatgcaga cgtttgaaaa tgcaaaagcc ggcgatatcg tccaggccct cgccgaacgg
   279001 atcatcgaaa accgtgctta tctgagtgag atcgacggca agatcggtga cggcgatcac
   279061 ggcgtaaaca tggccaaggg cttcggcctt gccgcggaac gactgaagga caaggacgcc
   279121 tcgcttgcag aggcgctcga aacgctcggc accgtgctga tgacggagat cggcggctcg
   279181 atgggcccgc tctacggcgt gatgttcacc gagttcgccg agaagatcga ggcggtcgac
   279241 gcgatcgatg cgaccgccta tagccgcatg cttcacgccg gactggaagg catccaatcc
   279301 atcggctccg cgaaagtcgg cgacaagaca ctgctcgaca gtttcgtgcc ggccgtcgaa
   279361 gctttcgacg cggcgatcgc cgccggcagg tctttcgccg aagcgctcga agcgctcaca
   279421 gcggcagcgg aagccgggcg tgattcgacc cgcgatctgg ttgcaaagat aggcagggcg
   279481 agccgcctgg gcgaacgctc cctcggcgtg ctcgacgcgg gcgcgacctc ctgtgcgatt
   279541 atcctgaggg agttgtcggg aggggcccgc gcccggctcc gctgacgccc ccagggcgaa
   279601 ttcccctaca gggcagcatc ggcgcaattc ccgccccatt gcaaaagcac ggcgttgctt
   279661 ccatcctcgc ggccgaaaca aggggaagta cacgactgca tgacgatgaa gacaccctca
   279721 ccgcgcaaag gcggagccaa ccgaggcggc acgatggacg gctcggacgc gatccccttg
   279781 cgttacggtg acgatcctta tgtctgggcc tgctggcttt attacgaaga cggcatgacg
   279841 caaagcgaga tcgcggaggc gatgggtgtg tcgcgcgcga cggtcaacag ctatctggcc
   279901 gacgcccgtg aaaagggcat cgtcaacatt tcgatcgagc cggcgcgcct ggcgtcgctc
   279961 acggtcgcac aggaactgaa gcggcatttc ggcctgaccg attgcctcgt ggttccgagc
   280021 gacgacaatg cgcgtccgct gatcgatcgc ctcggggcgg caggagcgca ggcgctgccg
   280081 aagctcctga aatccggcga cacgcttgcc gtcgcctggg gccgcaccgt tctttcggtt
   280141 ggcgaacacg ccggaatcac gtctcttcag gacatgaccg tggttcaggc gacaggaggc
   280201 accacggcgt cctttccgta tacgccggaa ctttgcgcct ctgccgtggc gcgggcaatc
   280261 gccgcccgct gcgtcaatat caccgcgccg gctgtggtca ggtcgcccga gctcctgcag
   280321 atgcttctgg acgaacccct tgtgcgggaa cagtttgcga ccttggcgcg gtcaaaccgg
   280381 gtgctcttcg gcatatcgtc gcttaggccg aattccacca tccacaccag cggcttcttc
   280441 gaatcggttt cgttacagga ctatctcgcg gccggcgcgg tcggcgtcgt cgccggccgc
   280501 ttcatcgacg agcgcggccg cccggttgcg gggccgctcg accaccggac ggtgggcatc
   280561 tcccttgacc tgcttcgcag gatcggcacg cgcatcgcag tggccggcgg ctttgacaag
   280621 gttccggcgc tgctggcggc gttgcgcggt ggctatgtca acgtgctgat cacggacgct
   280681 gcgacaggtc acggtatctt gcgcgcagac ggcggcacgg cactcgacag caggctttcg
   280741 caccgtccaa aactcgtgca gacgctgagc acctaccgca gccatgtcaa gaaattcctc
   280801 aacaatccga acgaggttgt cgaagagatg ctcgacggcg tcgtcaaagc gcacgagaaa
   280861 tatcttaagc cgatcaacgg atcgcatcga gcgctcgccg ctcgcagcgg gccgcggccg
   280921 gaaaaggtcg gcctcgtcat cggcggaggc acgggtcacg aaccgtgctt cctcggctat
   280981 gtaggcaagg gtcttgccga tgcggttgcc gtcggtaaca tcttttcctc gccgccgccc
   281041 gatccgatcg tacaatgcgc cgaagcagcg tccggtggag caggtgtgct cttcgtctac
   281101 ggcaattacg ccggcgacgt gatgaatttc gagatggccg ccgagatcgc cgaagaaaaa
   281161 ggcattcgcg tgcagaccgt cctgacgacc gacgacattg catcctcgcc gatcgaggac
   281221 cgcgaaggcc gacgcggcgt cgccggcaac ttcttcatct tcaagatcgc cggcgcggct
   281281 tgcgaccgtg gtctttcgct ggaagcctgc gcggcggtta cgcgcaaggc gaacctgcgc
   281341 acctacacga tgggggtcgc gctcgagccc ggcgcaatgc cgcagacgcg ccggcacaat
   281401 ttcgagatag gcccggaaga catggaggtc ggtatgggaa tccacggcga gccgggcgtg
   281461 acacgcgagc gcatcagatc ggcggacgag ataaccgaca gcgtcatgga ccgcgtcttc
   281521 aacgagatga aggcagcacc cggcgaccgc gttgccgtgc tcgtcaattc ctttggagcg
   281581 acgcccctga tggaactcta catcctgttt cggcgggttc agcagcgcct ggcggcaaaa
   281641 gacattctga tcgaagccaa ttggatcgga cactactgca cctcgctgga tatggtcggt
   281701 gcttcgatca ccatcctcca tctcgatcag gagctgtcag aactgcttca tcacccttgc
   281761 gaaacggcat tcctgaagat caactagggc gtttccggag aaaatgtgta acggtccccc
   281821 gtgcaagtca taaagggctg gagcgctgca gatggtagag tttctaggcg ccaagggccg
   281881 cgggaggaaa tgatgtcgga aatcgcggtg cgccgcctga tcgaaatgtt tgacgcgatc
   281941 tccagtgaca tcggggcgga gagagatcgc ctgtctgagc ttgacggcgc gatcggcgac
   282001 gccgatcacg ggatcaccat ggcgatcggc ttttctgccg tgaccagcga acttgcgaga
   282061 acggatgcaa gcagcgccga gctgagcagc gtcatgacgg cggccgcaag cgcattcctg
   282121 aatgccgttg gcgcttccac gggtccgctt tacgccacgg ccttccgccg ggcggcgcag
   282181 gctctggaag gatgcgatgc gctggatctc gggacttgcg cccttcttgt ccagtcgatc
   282241 gcatccggca tccgcgagcg gggcaaaggc cagcgaggcg acaagaccat gctcgacgtc
   282301 tggcttccgg ccgccgacgc tgctgcgcag gcgatcgctg ccggcaagcc cgccgatgcg
   282361 ttctgggcgg acgtcacagc ggctgcccaa aacggcgcca acgcgacacg ttccatggtt
   282421 gcgacaaaag gccgtgcggc ccggcttgga gaacgctcgc tcggccacat ggaccccggc
   282481 gccgcctcgg ccgtcctgat catcggcgcc atggcgcgaa ctctgcggta gagcgaaagc
   282541 ctcgcgggaa tactcttccc gcggccaggg actcgcctct gccgcacctc gcggccacag
   282601 cgtcgtccgt gaactatccg tactctgttg acaacactat gtaatctgcg ctttccggcg
   282661 gcgcagtgtt gcaagaaaag ctctggttaa gaacggtttt cctgcaattt gattttgcgg
   282721 ttttctggtc cggcgcggcg tgattcactt gttttagcgg cggtgaatcg aggagcggcg
   282781 atgtcgagac cacgcgagcg gcgcgagacg ggggagcagg atctgttccg ctcccggctg
   282841 gatcagatca tcaacatgag gcacgaactg gtgcggctgg cgcaggcgat cgactggccg
   282901 ctgttggagg gccgcttcgg cgaggtctat tgcgatggcc ccggcatgcc gccgctgccg
   282961 acgcggctga tggcggggct ggcgatcctt aagcacacgt tcgacctgtc ggacgaggag
   283021 ttgtgtgccc gctgggtgga gaacccctat ttccagtatc tctgcggcga ggaattcttc
   283081 cgccacgacc tgcccttcga ccgctcgtcg atgacgcgct ggcgggcgcg catgggcgag
   283141 gagcgactga cggcgctgtt gcaggaaagc ctggcggtgg cggtcaagac cggggcgatg
   283201 cagccgcagg atacgcgccg ggtaatcgtc gacaccaccg tgcagccgaa gaacgtgatg
   283261 tttccgaccg acgcgaaact cctccatcgg gcgcgcgagc ggctcgtccg cctagccaaa
   283321 aaggcagggt tgaccttgcg gcaatcctac atacgggtcg gcaagctggc gctgatcaag
   283381 caccagcgct acgcccacgc caaacagttc aaacgggcca acaaggcgtt gcggacgctc
   283441 aggacctatc tcggccgcac cattcgcgac attcgccgcc agatcggcga tgatgagaag
   283501 ctgcggtcga tcttcctgtg gccgctgcac caggcctcga cggttctgga gcagaggcaa
   283561 cgccagcgcg gccgcaagat ctacagcctg catgcgccgg aggtcgaatg catcggcaag
   283621 ggcaaggcgc accggccgta cgagttcggc gtcaaggtct cggtcgccac cacgctgaaa
   283681 cgttcgaagg gtggccagtt cgccctgcat gcgaaagcca tgcccggcaa tccctatgac
   283741 ggccatacgc tggcaacggt gatcccggag atggagaaaa ccgtcggcaa tgagatcgcc
   283801 cgcatcctcg ccgacgccgg ctaccgcggc cacaatgccc ccgccagcca ccggttccgg
   283861 atcttcacca gcggtcagaa acgccgcgtc acgctagcga tcaagcgcga gatgcggcgg
   283921 cgttcggcca tcgagccggt catcggtcat ctcaaggcag agcaccgcat gggccgcaac
   283981 tacctcgcag gccaacacgg tgacgccatc aacgctgtgt tggcagcagc cggctacaac
   284041 ttctcgctcc tcctcaactg gttgaggcaa tttttttggc tgctcttcgc ctgggtgcac
   284101 gccgcagcca atccgaacgc tgcttagcgc cgatcattgt tcacggtcga ccacagcggc
   284161 cggtaaatct gacgcgctac cccgcctcgg gcgcagccgg cccatcaccc gctgtcagca
   284221 tctgcatcag cgcaagttcg ctccttacgc ctttctggta gaggtgaaac agcattttac
   284281 caacttccgc accgtgttcg ctgtccggct ccaattccct gaaggagcag gcataggcat
   284341 gaacgcgtcg caacatcgag atttcgtcgt cgcccatggc gatatccgag aagcgcaacc
   284401 acatttcctt tgaccctccg atcaaagcag gtttgttgat gatctgacat catattggtg
   284461 cggatgtcgc gcaaatccag aggccgcgac attcttctga ggaggcattc atgtcacggc
   284521 gcaccaaccg tttcaaggat gctgaagcgc cctctgcttt tcacagagcc agagcaagtc
   284581 cttgggctga aaagacccct tcgcgccgca gacgcggcgc tgcttcatcc tgtgacgaac
   284641 acagagatgc ccccgatacg cgacctaaag ctcgaaaggg tcgttggcgc tctttttgtc
   284701 cggcgcggcc tcgaatgggt ccttgggcga ttggggcgtg ctgcgtgccg aggcggcagc
   284761 attgactgac tcctgacaat tgatcatttc agtgactgca cgtgccgaac ccttaaggcc
   284821 aagggccgct acctcgcgac cgttgaaggt cgcgcgcatt cctagcttcc ggctgaactc
   284881 ctcggcgaag ttcgtgtcgg tggtagaaac cgacaggaag ttgatgccgc caaaatcgat
   284941 cccctgggca gtggcgttcc agacgggatt tctgtcgaac tggatttgga ccgggtaatc
   285001 cttgcccacc tcgagagact tccagtcgct gtttccgagt gccaggtaga tcttcgtctg
   285061 gctttggaag aaattgaagc ccaggcggag gatggtgccg tcctcataca tcgtcgagat
   285121 gaaacaacca ttgccagtgg aaggatctat caggacgctc cacccgctga catctttcca
   285181 gggaatggtt tgcgcagcac aaaccggtgc cgtcaacaac agaccgccga atattaacgc
   285241 cgatgcgccc ctcatgcatc tctccctctg gttgcagagg ttacgatagg caacgagagg
   285301 aaaaaggcaa ccgtcctaag accacgacaa ggctacgttt ttttcgcctt ccacttgtct
   285361 tttgacctgc ctcctatagt tgaagtgcag acaacgcctc cgcgaaagga caaaagacat
   285421 gtcggtattg atcagcatcc tgatcacctt cctcgtcgtc attctggttc tctatctcgt
   285481 caaccgcctt tccctcgatg cgcgcaccaa gcagatcgtt caggcgatcg tgatcatcat
   285541 cggcatattg tcgctgctgc ggtatctcgc ggtgttctga cgcgtgcgac agcaaaaacg
   285601 cggacgccgg agcaagtgtt acagactgtt ggccgtctga atgcgtgctt gagggggcgg
   285661 ctgaacgaag ccactggtaa cgtccggagc gtttgcctcg gaaagctgcg acaggaattg
   285721 ctccatgagc gcggtgtcgc cgaaccggcg cagggcgcgc tcgctggcca gggaaaattc
   285781 gggatctgct tcggtcagcc gcgccatggt gcgctgcgcc ccctgggcgt ctccacgctg
   285841 gctcaggacg gccgtctgga tcagcaggca atccggttcg cgcggcgccc ggatcaggca
   285901 ttcgcgcaag acctcatcgg cttcatcgag gcggccggca gcataaagcg cctggccgta
   285961 cacataggta tagtattccg gcgccatcgg atgcagccgc cgggcccgct cggcgttttg
   286021 cacagcctcg tcatagctgc cgaatctgac ctgcgccttg gccagtgcca tgaggctgtc
   286081 cggatcgttg ggattgagct cgaccgcgcg ttgtgccgcc tgcatggcgc cgggatagtc
   286141 cccggtggcc gagaggccga agctgagcac ctggtacccg actgcgaggt tcggatcgag
   286201 gcggacggcc tgccgcgact cgctaagccc tgtttccaca tcggtcacgg tcgcccggcc
   286261 ggtgaggttc tgcacgaagt ctacgatgta ggtcattccg agactggcgc gcgctgcggc
   286321 atagccagga tcgagttcga gtgccctatg aagcaacgca cgagaagcga tcagcgcctc
   286381 ggcgtctttc gaaccatgct tgtaacggtt acgcgcctgc aggacgagat cgtaggcttg
   286441 aaggttctcg gtgggctgtt ccgccgcgtt cgatacttcc gactcgcgca cataggaaac
   286501 gagatgcgac acgatctcgg ccgtcagctc ggtctggacc gagaaaatgt cctcgacccg
   286561 gcggtcgtaa ctgcgcgacc acagatgcgc accgctgcgc gcatcgatca actgcgccac
   286621 gacgcggagc tggtctccgg cgcgccgggc actgccttcc accacatagc cggcgccaag
   286681 cctttcgccg atccggcgaa tgtcctcggc ctggccgcga agggcgaagg tggaattgcg
   286741 ggcgatcacc tgaagctcgc gatttctcgc gagattggcg attatgtctt ccgtaagccc
   286801 atcggcgaaa taggcctgat cggcgccgcc gctcatatca tcgaacggca gaaccgcgac
   286861 cgtcggcctt gcatcggcaa gctccgcacc ggtcagacgt ccgaagctat cgaccatgtc
   286921 cgcgccgatc gctctcaccg caggcgcctg ggtggcagcg gcgataagga caaatgctgc
   286981 ggctccgata gcatagggca aggcggcgcg gcgcccgcga gccgtccgtc caaaccagcc
   287041 gctggggctt tcctcatccg ccccaagccg cacggcatag acggcgagcg gctcgggaat
   287101 gttcttcgcc tgccttcgcc cgatgctgta gaagagcttg cttcggttcc ggtcagcgct
   287161 gcgaaccacg gcttcgctca caaaaatgcc gccgggctcg gccatggctt ctagccgcga
   287221 cgcgacattc acgccgtcgc cgaacatgtc gccatcgact tcaatgacgt caccgagatt
   287281 gatgccgagg cgcatgtcga agggccgatc cgcaaatccg ttctggatct cgattgcggc
   287341 gtcaagggcc tcgttgacgc tcggaaacgt cgcgagaaaa ccatcgcccg tggtcttgaa
   287401 tgttcggccg ccgtgcttct cgaccgcagg tgtgatcagc gcgctgaaaa cctcccgcaa
   287461 tgcggaatag gtcgaggact cgtcctcgga catcagccgg gtatagccga cgatgtcgcc
   287521 tgctacgatt gctgcgagtt tgcgttccat cacgagcctc gacagtcttc acgcgcatct
   287581 ttatgggacc gaacccgccc gtccactcaa aactccgtgt ccgaacgtcg cctgagccca
   287641 tcctggagat cgacgcgtgc gctcccgatt gccgctgacg aaaaactgta cgaaggccgt
   287701 gagaggaatg cgaagaaggc aggatgcgaa cggactgacc catgctgcac atggattgcg
   287761 gcctttgggt ggcacagttc acatcagccg gtcagcccgc tcgcagccct gccgctttca
   287821 cgccaggcga ggacaggcgc caaggcttcg cgaagtgctg cgagatccgc ctcttcgacc
   287881 ttgcggaagg ggcgccgcga tcgaccggac gcaatgccca taatgccgag caacgccttc
   287941 gaccccggca tgacaccgac cttgatcagc acctggatca cgcggttcgc catggcctgc
   288001 agctgccgcg cctccactat ccgccccgcc gctgcacagg ccctgagcga gacaaacaca
   288061 tcgcccatga agttataggt tgtgccgatc gcgccctgtg cgcccatagc gaagccggcg
   288121 aggcacattt cgtcgtaacc gttatagacg attgcatcag gggcagcatt ccggagacgt
   288181 tcgagctgga acatgtcgct cgacgtgtgc ttgattccga tgatgttggg atgcgagaga
   288241 agctcgacca gttcgggcaa agtgaagccg ctcgtgcggg ccgggaaatt atagacgatg
   288301 agaggcaagg cggaagcgtc tgccagctcg cggtaatgcg ccatgacctc ggggcgggaa
   288361 aaatcgtaat agaagggcgg gattgccgag atcgcctgat agccggattt ggccgcgtgc
   288421 tgcgataggc tgagcgcatc tttcgtcgcg atcgtgccta tgtgagcgat cagcttcaga
   288481 cggccggcgc ccgcggccgc gacgtcggaa agatagtcgg cccgctcgtc gagcgactgc
   288541 agcatcgctt cgcccgagct gccgccgaca tagaccccat ctatgcccag gccgacctgg
   288601 aaatcgacga gtgctccgac ggcctgccgg tcgatggctt cgtcttcaga gaacggggtg
   288661 aggagggctg aaaagatccc ttcgagttgc atcgttttgt cgctttcact ggttcatgga
   288721 aaaaagttcg ggcaattgcc ggcgggcggc gccgccaagc tcggcaaccg cttcctcggg
   288781 ggcgcaactg tagggccaga gcaggtgtgg ccccatggaa caccagcggc cggctgcagc
   288841 cagcgccttg tcgagcgcgg cattcgacag gccatagcgt actgcaagcg gcaggacctg
   288901 ctcgttcatg aaggcgatga cgcgcgactc gaacgccagg gcgcccgccg ggtcctcgcg
   288961 aagctgacgc caccagccga gagcgccggc ggggctcaga caggcgacat tcgaatagga
   289021 gccccggccg ccggcgaggc agccgctggc catgaaatgc ccgggaataa agacggaaaa
   289081 gtccggaagt ttgcgccgaa gttcctcgta ccagaattca tcaccgcccg gcagcttggc
   289141 gccgatgagc gtagggatcg cagtcctgag ctttgcgatc tcgccgtggc tcagccggcg
   289201 cttggcatgg ggcggattat agaggaccag cggaacctcg ggcgccgttg ccgccattcc
   289261 ggccagaaag gcctccgcct cttcgtagct cggcgcccac cagtcgggca aagtgacctg
   289321 agcggcgtcg ggacgcagag acgcgatgcg ggccagccgt tcgcgcgcaa ctcgggcatt
   289381 cgaatgcgaa acgccgatct ggaagggcag agcgacgaga cggcagaact cggcgaccaa
   289441 ttggctcagc cgatcgaatt cctgctcggt ctggctgtgg aactcgccgg cggtgccgtt
   289501 tgtgtatatg ccctcgagcc cgctttcatg aagtgtggat agctgctcgt gcaaggcgga
   289561 ccattcaatc tccccgcgtc ggtcgatcgg caggagcacc gctccccaga tgccttcagg
   289621 ccgtttggcg cagatgctca tcgggcagct ccgagcatct ggtcgggtat gaaggtgacg
   289681 agcgcgggga acagggtgat cagtaccagg acgaggacga gcggaacgag cagaggcagg
   289741 atgccgcgtg caagcaggcc gaagggaata tcggcgacct tggacacgac gaaaagcgcc
   289801 acacccatag gcggcgtcag aatgccgatc atcaggttga acacgaccat gacaccgaaa
   289861 tggacgggat ccaccccgaa ctgaagcgcg gtcggcacca gtaccggcac gatgagaagc
   289921 aggatggcga gcgcctctat gaaggttccg agcgcgagaa gcatgagatt gaccaggatc
   289981 agaaaggtca acgggtcatc ggcatacgca aggaagaacg cggcgacgtg ctgaggcacc
   290041 tgctcccgtg cgatcacata gccgaacagc gacaccccca tgatgaggag gccgacggcg
   290101 gccgtatggc tgacggtctc acgcaagaca atcaccagtt tggcgaaggt aatttcacgg
   290161 tagaccacga ccccgaggaa gagagcatag ctggctgcaa ccaccgcggc ctcggtcggc
   290221 gagaatatcc ccgcaaagat gccgccgata atgatgaacg gggtaatgag cggaagcagc
   290281 gcacgccaga aggtggacca gatccggcga aggctggagc gctcttcggt cgggtagttc
   290341 cggcgccagg cgatcacata aaccatgacc atcagcgaga ttgcgcagag gaggcccggc
   290401 acgatgccgc ccaggaaaag gccgcctatc gaggtattgg cgatcacccc ataaaccacg
   290461 aggggaatgg agggtggaat cagcggacct atgatcgccg atgcggcggt caccgaaccg
   290521 gaaaactgct cgtcatagcc ggcgtcacgc atcgccttga tctcaagctg gccgaggccc
   290581 gccgcatcgg cgactgccga accggacatg ccggagaaca ttacgctcgc catgatgttt
   290641 acatggccga gcccgcccct gacatgcccg accagagcct tggcgaaggc gaatatgcgc
   290701 tcggtcacgc ccgaaagatt catcaattgc gcggtgagaa tgaagaaggg aacggcaagc
   290761 agcggaaaac tgttgaggcc ggcaatcatg cgctggccgg caaagttcag gcccgttccc
   290821 tgccagagca tataggcaag cgccgccacg atcagcgtaa agccgaccgg cataccggcg
   290881 accagaaggg caaaccagcc cccaaagagc gtcgtcatca gagatacctt tcggatgggg
   290941 catcgacggc cgggcggccg ctgtcgaata gcagccgcac atcccgcgcc atgacaagca
   291001 gtatccggat agcagccagc agcccgaaga ctggcaaggc gccgtaaagc cacgattccg
   291061 gcacgccgat ggcgatcgac atgaccttgt gggcacgcat ggcgccgaag atgccgtagt
   291121 aaacgaggac gagcagcgcg gcgagcacca cgagatccag aacgagccgc agaagcagtt
   291181 gtacgcgctc cgggagcata cgcggcacga tatccatggt gatgtgcgtc cgtgaggtga
   291241 cgccctcggc ggccccgagc gccacgagcc acacgaaggc ataacgcgca gcttcctccg
   291301 tccagaacat cggatcacgg aagacgaagc gggtgacgat ctgcagcgca atcacaacga
   291361 aggcgaagac cagaaggatc gcagccaatg tctcttcgat gtgggcaagg ctccgccggc
   291421 ggcttgaagc agccattgtt gaactccctg gaatggagaa ggcgtggcga ccagccgcgc
   291481 ctgcggggtg gctggctaca ggtcggcccc gacctgtagc cgtcgctatt tatcggagat
   291541 cgagcagcgt ctgtaccgtg cccgcgccga acctcgcatc gagatcggca tagacgggct
   291601 tcatcgcctc ctggaaagct gccttgtcgg gttcgaccac ggtgattccg cgctcacgaa
   291661 aatcgctgac gagactcgtt tccttattgg caaccagctt gtcgttgagg gccccgccag
   291721 cctcgaatgc ctccatgacg agtttctgat cggagggatc aagcgcattc cacgtatcct
   291781 ccgacatgag gacgacctgg tcctgcacca gatgcccggt caacgaaaca tgggtctgca
   291841 cctcggtgaa tttcatcgag tcgatgatcg gcagcgggtt ttcctgacca tccacctgat
   291901 tggtctggag cgccagatag acttcggcga acgcgaccgg ggtcgggctc gcgcccattg
   291961 ccttcgccca ggtcagaagc ggcgcggaat tcggtacgcg cagcttcatg ccgttgaaat
   292021 ccgcaggctt ttcgatgggc ttctttgccg tcgtgtgccg cgttccgaaa taccaggagt
   292081 cgaccatgcg ccacttgtgc tcggttcgca attcgtcgac gatccccttg ccccagtccg
   292141 aggcgatgat cttttgaaga tgctcgaagt cgccgacgac ataggcagta ctcgccaaca
   292201 cggcccgggg aacccaggca tccatgcccc cgaatggatt gagcgtgaag tcgagttcgc
   292261 cgagtgtcac ctgctccatc atctcggtaa aggtgccgag ttgcgaattg gggaagattt
   292321 ccagcgtcag ccgaccgccg gacttttcct tgatgatgcg cgcggcctcg gtgacaccct
   292381 cgaattgcgg gtccccggcc gtgccttgca tccccaggcg cagcgtgcgc gcctcttgag
   292441 ccatggcttg cgaagccatg agcagccccg caagcgcgag cgaaatcaat ccttttttca
   292501 tcgactactc ctccctttat aggcctcccg catcggcccg aaatcggttt cgattttcgc
   292561 gaagcacgat gcgtcggttc aaatggatta aagcgcctgc cgcacgtcca ttcgcaggca
   292621 cggcgctcta agggttcgtt tgcctgtatt tgcgcgcggc actctccagg tgctcacgca
   292681 tgacacgtcc ggcatgctcc ggatcgcgtg ctcggatcgc ctccacgatc gccacgtgct
   292741 cgtcgaaact ctctctgttc gaaatctccg gtttggtcgg cagcggcctt tggccgatca
   292801 gccagtcgac aaacgcgtcg tgtaccgcga cgaaaatcgg gttcgaaacc atctgggtca
   292861 gcgtgcggtg gaaggcgacg tcggttgcgg caaaggcgcg agccttgccg atcgcagcct
   292921 cgttgcgagc aagcgccgcg tcgatcgccg caatctgctc cgccgtggca tacgccgcca
   292981 gatgccgcgc gcagccctcc tcgagaaaca agcgcgcctg ttcgaagttc gccacaccct
   293041 ccgggcgtcc gagaagcatg cgcgcagcac ccgcaagcga agtcaggaaa tggtccggcg
   293101 tcgggcgcgt gactttggcg cgctcgccgg tgctgatctt cacgagcccc atgcgctcca
   293161 gcgcatacag cgcttcgcgg atcgaggggc gcccgacgcc gaacagctcc atcagatccc
   293221 gctcggaggg aagggtggaa tcgagaggat agatctcgtc gcggatcatc tcctccagct
   293281 tcaaccggac ttcatcagaa agcttcttgc ggactgcgag tgtgctcatg gtataattgt
   293341 taagctgtta taccagcgag agtcaagagg gcatcgggcc gcgcttattg accgagcacg
   293401 cggagagtgg cgctcggcat caacggcgca cgtcttccac tcagcggctc gcgaatagct
   293461 ccttgggcaa ggcgccgcga gcttcaatgc cgacgaacaa aatatccgat cgcgaggccg
   293521 aggccggcga gtaacaaaaa agtctggagg gagctgcgag gttcggcggc gcttgggcgc
   293581 tccccgacat tcctctcttc cggcgtatca acgaccttgg tgtgcggacg atcgaagccg
   293641 gacgcaacct gctcatgcca ccggccgtcg gtatcctgaa actcgatctc ctcggtcgag
   293701 ccgggaagct catgatggcg cgcggcgatc tcggctgcag ccagagcatc ggcgtgagtg
   293761 gcgaaagctt cggaaaagac gtcgtccact ttgtaagccc agcccccgtc gtgctctaca
   293821 atttcatatc gtattgttgc catggcggtg ctcccgttag atgggaggaa acatcctgac
   293881 atggccttgg ttcccccaac gccgcattcc ggcggaccga ttatgggaga ttgccacgga
   293941 aattcgccac ggctatcgag agaatgccac cgatcggctg acatccggca acacgccgat
   294001 ttacgcaaat accccccttg cttgataaag cgcaacgatc gtaacatgcg cgcacgtgcc
   294061 cttctgcgtg taatgcaaac tgccgctgcg acctttacgc gtccgataag gcgcgtggca
   294121 ctgcaaacac aaaattcgga acggctgcag cggcacgcga gataccaagg gagaaataga
   294181 tgagacatga acggattacg ttgcgaggag cgcagatcgc cgccctctcg gctgcgatgt
   294241 ttttttcggg cagcgcggtg gcgcagcaga aattcgtgac gatcggcact ggcggcgtca
   294301 ccggcgtcta ttatgcagcg ggcggcgcca tctgccggct cctgaacaag gaccgcaaga
   294361 cgcacggaat tcgctgttcg gtcgaatcca ccggtggatc ggcgttcaac gtgaatacga
   294421 tcaaggaagg cgagctcgat ttcggcacga cacagtccga cgtccagtac aacgccatga
   294481 agggcgagga atcgttcaag gaaggcggcg cgcataccga cctcagagcg gtattctcga
   294541 tccatcccga accattcacc gtactggctc atccgaatgc cggcgtgacc aggttcgagg
   294601 atttcaaggg caagcgcttc aatgtgggca atccgggctc cggcacgcgc gcttcgatgg
   294661 aacgtctgct cggcgcgatg ggctggacgc tggccgactt ctccctcgca tccgagctca
   294721 aggccgatga gcacgggccg gcgctttgcg acggcaagat cgacggcttt ttctacggcg
   294781 tcggacatcc ctcggccaat atccaggatc cgacgaccac atgcggcgca aagctggtgc
   294841 cgctgaccgg cgaagtcgtc gacaaactgg tcgccgaaaa cccctattat gcaaaggcga
   294901 ccattcccgg cggcctctac aacggcaatc cggaagacac ggaaacgttt ggcgttcttg
   294961 ccacgctggt cacatcggcc aatgtaccgg aagagagcgt ttacgaactc acgaaagcgg
   295021 ttttcgagaa cttcgacgag ttcaagtcgc tgcacccggc cttcgccaat ctcgatcccg
   295081 ccaagatgat caaggatggc ctctcggcgc cgctgcaccc cggcgcggaa agatactaca
   295141 aggaaaaggg ctggctgaag tgagcctcgc cagctaatgg cttaagccac acccgtccgg
   295201 gcgaaaaccg gtaaacaggt ccctggacgt tattctaccg gcgggcagag cgctgtccgc
   295261 cggcaacatt caatgtgggg agggtgccac gagcgagctt caagaacgaa aggtcgatgt
   295321 cgacctcgag cagctggttg ccgaagcgga taccggcgga cgcaacgcca aggggttgac
   295381 ggggctgata ttgctctgca ccgctgtcgc ctggtcgctg ttccagctct ggtacgcgtc
   295441 cccactgccc ttcgtcttcg gtttcggcat cctgaacgat accgaagccc gcgccatcca
   295501 tctcggtttt gcgctgttcc tgacctttct tgcctacccc gcactgagaa gctcgccgcg
   295561 tgaccgggtg ccgctcgccg actgggtgct ggcggcactc ggcgcctttg cgggcgccta
   295621 cctgttcatc ttctacggcg atctggccgg acgaccgggc caaccttcga cactcgatct
   295681 cgtcaccggc accatcggca tcctgctcct gctggaggcc acgcgtcgcg cgctcggcct
   295741 gccaatggtg atcgtcgccg gcgtcttcat cttctacacc tttgccggcc agtacatgcc
   295801 ggacgttatc cagcatcgcg gcgcctccct ggtgaaattc atcaatcacc aatggctgac
   295861 gacggagggc gtgttcggca ttgcgctcgg cgtttcgacg agcttcgtct tcctctttgt
   295921 cctgttcgga acgctgctcg agaaggcggg ggccggcaac tggatgatgc agatttccat
   295981 cgcattgctc ggacacctgc gcggcggccc cgccaaggtg gccgttgtct cctcggccct
   296041 gaacggcgtc gtctccggct cgtcggtgtc caatgtcgtc tctggcggca tctttaccat
   296101 tccactgatg aaacgcaccg ggctttccgg cgtaaaggcc ggcgcgatcg aggccagcgc
   296161 ctcgataaac ggtcagatca tgccgccggt catgggcgcc gccgcatttc tcatggtcga
   296221 atatgttgga atcccctatt cggagatcgt caagcacgcg ttgctgccgg ccgtcttctc
   296281 ctacatcgcg cttctctaca tggtgcatct ggagtccgtt aagctcgaca tgcaaccgat
   296341 cccccagcgt ccgactccgg cgcgcgagcg gtggatccgc atgggcctag ggctcaccgg
   296401 cagcgtcctt gcagtctgcc ttctctatta cgggatcctc ggcatacggg cggccttcgg
   296461 ggcaaacgca cccttgctgc tcgcaatcgg aggcgcggcg ctttacatcg caacgatctg
   296521 gtattcgtcg cgctatcccg atctggagct cgacgacccc aacgcgccga tactggagct
   296581 gccgcgggca tgggacgtaa cgcgaaccgg cctcgacttc ctcattccga tcgccgtcct
   296641 gctctggtgc ctcatggtcg agcagctctc gcccgggctt tccgcctttt gggccaccgt
   296701 gacgatcctc gccatcgtcg ccacccgcaa gccgctgatg gcgatcttcc gcaaggagga
   296761 tttcgcaagc tccgtcggcg ccgctgcatg ggacctcgta gacggcctgg cgcttggcgc
   296821 gcgcaacatg atcggcatcg ccgtcgccac ggcgactgcc ggcatcgtcg tcgggacgat
   296881 cacgctgaca ggcctcggcc tgatgatgac cgagctggtc gaattcatct ccggcggcaa
   296941 cgtcatcatg atgcttattc tcatcgccgc aatcagcctt gtgctgggca tggggattcc
   297001 caccaccgcc aactacattc tggtagccac cctgatggcg ccggtcgtcg tcgagctcgg
   297061 ctcgcaggcg ggcctcgcca ttccgctgat cgcggtgcat ctcttcgtct tctatttcgg
   297121 catcatggcc gatatcacgc cgccggtggg gctggcctca tttgccgcag ctgcaatttc
   297181 caaggaagac cccatcgcga ccggtttcca gggcgcgctc tattcgctgc gcaccgcgat
   297241 cctgccgttc gtcttcatat tcaatccggc gatcctgctg atcggcgtcg atacctgggc
   297301 gcacacgatc tgggttgccg ccatctcgct cgccgctatc ctgctcttct cggccgcgac
   297361 gatgaactgg ttcgtgacga agagccgctt gtgggagagc gcggtcctgc ttctcgcctg
   297421 cttctcgctg ttccggccgg actggtgggt caatcagatc tcgccgcctt acgaggaatt
   297481 gccggcttcc gagttcctga ggacggtgca ggaggctccc gcaaaagctc gaatcaactt
   297541 cgtggttcaa ggcatcgacc ttatgggtga cgacgttcgc aagaccgtca acgtgccgct
   297601 cggcgaaccc ggcgaaccgc tgcagcgtct gcgggcgatc ggcctcacgg tcacaccggc
   297661 gggcgacagt ttgatgatca gcaatgtcgc cttcggatcc tatgccaagc gcatcggtct
   297721 cgatgtcggc tatgacgtcg tcgcagtgct gaagaaggcc gatcaaccct cgaccgctat
   297781 cccggtgagc atcgcgctga ttctgactgc aggcattgcc ggcctgcagt tcgcacgcaa
   297841 gagggccgat cgcagcggag ccagcctgcg gggaaccgca cgcaaataaa cggcagtcat
   297901 gtcgccgagg attcgcgcac gaccagtagc ggcggtgcga tcgggcgccg ctcgggatcc
   297961 ttgccttcca tcacggcgat cagcaggtcg attgccgctt ccgcgacctg atcaagatgc
   298021 aggttgacgg cagtcatttg cggcactgag agctttgccc gcattccgtc atatcgggtc
   298081 gcgagacgca gcccgagagg aacggaacgg ttgagcgacc gggcagcagt gagaacgccc
   298141 gttgcgaatg cgtcgaccgg gacacacagc gcatcgatat ccggattgcc tcgcaggagc
   298201 gtttcggcaa tggctgccgc ctcaccttcg ccaccgcttt cgttgacgcg caacgcgacg
   298261 ggcgtatagc cgttctccgc cgcgaaagcc gcgtagacgg cttcggtttc gatgtaggaa
   298321 tttcgccgtt gttcgccggt gatcaggccg acgcgacggt tattcgcacc aagatgctcc
   298381 agcatcagcc gggccgtcgc cgtgctttgg atatcgactg acgggatgtc gtcccgcccc
   298441 ggcgctctgc cgatcgagac aacgggaacg ccgcgggcgg agaagaattc cagcagcctg
   298501 tcgtcggacg tgggttcgac tataatggca ccatcgacct ccagcgcgtc aaggttggag
   298561 tccggctcca gaggcggcac caggcagagg gcgagatgcc gcgaaagggc cgtcacggcg
   298621 gccgcggcgg cgatctccat caggaagccc agcctggcag gaccggccgc gatcgcaaag
   298681 ggcatcgacg atgcaagggc gatgatccct gccccgccgg ttctgagcct gcgggcccgc
   298741 ggattggccc ggtaacccat tttgtccgcc agcgccacga tcctggcttt cgtctccggg
   298801 tcgacatagc gccgtccgct gaaggcgtgg gaaaccgtgg tcggcgatac gcctgccgcc
   298861 cgcgccagct caacgattgt ggatcttgcc atcattcacc tcgactctgc accgcccgga
   298921 tcgtggcacc cgcgcgcgaa tatagcaaat cgatttgcca aacgcgacaa atgtgctatt
   298981 gcttactatg caaaacgatt tgcatagccg gcgggagaga ggctggcgtg gaggagatca
   299041 atcaaatgac cgggaaaaaa atcgattcta tcgacccgac agaccaagcg ctgccaccac
   299101 gcagcctgat cctgttcggt ctgcagcatg tgctggtaat ggcggcgtca ccgataaccg
   299161 ccgtgtttct cgtaagcaag gcgctcgggt tttccgatgc gcttacggta tcgctgatca
   299221 gcgcgacatt tctgatctgt ggtttgggga caatcctgca gagcttcggc ccggcgggtt
   299281 tcggtgcgcg actgcccttt atcatggtgc cgggcggggc gccgattgcg atctttctcg
   299341 ctatcgccca gcaaaccgac atacagacgg cagtcggcgc ggtgatcctc acggccggct
   299401 tctatttcct ggcgctgccg gtattccggc ggctgctgcg ctattttccg cccatcgtgg
   299461 tcggcacaat gctcctgctc gtgtcggtga acctcgttcg catctacggc ggtacgatca
   299521 ccgggaaaca ggggagcgag ggttttgccg atccgatgaa tgtcgggctt gcccttgcga
   299581 cgatcgccct gacggtgatc ttcgccagga tttttacagg cacgtttcag cggatttcgg
   299641 tgatgctcgg gctcatagca ggttcgatga tcgcctttgg agccggctat atggacctct
   299701 ccggcatctt cgacggaccg gtcattgccg tgcccgcgct tcttccgttc gggatgccga
   299761 agttcgacat ctttgccgcc ctcccgctca tcgtgttttc catcatatcg atggccgaag
   299821 cgacgggcca gaccatcgcc actgccgaga tcgtcgggcg tcgcggcgat gcgcacgcaa
   299881 tcgtgccagc gaccatccgc ggcgatgccg tcgcctcgct tgtgggcggc ctgttcggaa
   299941 catcgctgat catcaccagc ggcgaaaacg tcggcattgt ccgggcgacc aacgtgaagt
   300001 cgcgttacgt caccgcaatg gctggcgtga tcctggtcct cattgccctg cttgcgccgg
   300061 tcggtcggct ggccaatgcc ctgcccggcc ctgtcgtcgg cggaaccgcg gtgatcgtgt
   300121 tctcgatcat cggcgtcatc gggatcgatc tcctgcgtcg cgtggacctg cgcgagcatg
   300181 gcccgatgtt cacactggcg gcggcactat ccatgggcct gctgcctatc cttgttcctg
   300241 gcgtctacag ccagtttccg cagtggagcc agatgatcct cgccaatggc cttgccgccg
   300301 gcacgatcac ggccgtgatc gtcaacgctt tcttccaaca catgccctcc ggctcggctc
   300361 aaaaggccgc cgccggcgtc gaggctgaaa tttaagggaa tgcagaagtg acggatttgc
   300421 gcgacaggtt tctgggcaac ggtgatttcc tgcttcaccc cggcaaggtc ctcttgccgg
   300481 aaggccctcg atccggaatc gggatagtgg tccgcaaggg gcgcttctcg gaaatcggtg
   300541 ccgcaggact tgtcggcagc cggaatcccg acctgaggcc gatagagttg ccgcatcatc
   300601 ttgtgatgcc aggcttcatc gacacccata cccatctgac ccagtccctg gggaagtcgc
   300661 tcgtcttcgg cgagccgtcc gagatctttc gccgtatctg ggtgccgctc gaaggcagtc
   300721 tggatgaacg gatggtctat ctttcggcaa agctggcggc gcttgaatgc ctgcgcggcg
   300781 gctttaccgc cgcagtcgat gcgggcacgc gttccgcggg ccacatggac gcgctgatac
   300841 gggcggcgcg tgaaaccggc ttgcgtagcg tcataggact tatctgcaac gatctcggcg
   300901 gagccgcggt ggtccccgac cgcacgacga tcctcaggaa tgcggccgga catctggccg
   300961 cattcgaggg cgattcgctc gtacatccct cactcgccat ttccattccc gaggcggcca
   301021 gcgaccacat gctggctgac gtctccagca tggcgcggga agcgggtgtc atattccaga
   301081 cccatgtcaa cgaacacctc gtcgcagtcg agcgctcgct ggttgcaaac ggccgccgtc
   301141 cgctggagca tctcgctcat ctcggcgcac tcggcccgca tgtgctgatc gcccattcca
   301201 cgctggtgac accgcacgaa ctgaacctgt tgcgccacag cgatacggcg gtcgcataca
   301261 atccggtggc gagcttgtgg aaaggcaatg ccatcgcacc cgcgctgcaa atggccgcac
   301321 tcgggatccg cttcggactg ggaaccgacg gcacccgcgc agacggtttc cgcctcatgg
   301381 atgccgccga gggcctgcag cgcgccggct tcgggcttgc gacgggcgac tcttcctgtg
   301441 gaggcggctg gctctggatc gaccgggcaa cagcccaggc ggcggatgcc gcaggtcttg
   301501 gctgcgtgac cggcgcgatc cgcgagaagc ttgcggccga tttcctcctg gtggatctcg
   301561 accgtcccga attcacgccc tcccacgatc tcatgtggga actcgtgcgc tacggcaacc
   301621 gcgaccagat cgacgccgtc ttcaccgccg gaatgcttcg cctctggcaa ggctggccgg
   301681 tccaatggga tgcacgcgcg cttcttgccg aggtgcgcga ggtcacggcc gatgccatag
   301741 caagggcgcc gatccagcgc gtacacaagc catcggcgga gcaccgggcg ctggggcatt
   301801 tcgcatgaca ctcagccttt ttgcgatttt gagcgcggtc acattggtct cggcatttat
   301861 ccagggtgct ctcggcatcg gcttcgcgct catcgtggcg ccggtcgtcg gcatcctgca
   301921 gcccgatctc ctgccggtga cgctgcttct cttgatgctg cctctcaatc tccacgtcgc
   301981 ctggcgcgag cggtcggccg tcgattggtc cggcgcgaaa tggatcagcc tcggcaggtt
   302041 cgccggcacc tttgccggcg tgtggctgct cgccgccttg tcgagccagc agctcgacct
   302101 tgccgtcggc tggtttacgg tcattgccgc cgccgcagcg cttttcgccc ccccctttgc
   302161 gcccggtcga ccgagcgcgc tcggtgtcgg cttgttcacc ggcgtaaccg aaacggcgac
   302221 cggcatcggc gggccaccgc tcgctctcct ctaccagcac gccaagggcc cgatactccg
   302281 ggcgaccgtg gcggtgtgtt tcttcgtggg ggaaatcatg tcgctggtca tactcgccat
   302341 tgccggccgc atcggagcgg accagcttct ggccgctctc tacctcgcac cggcggtcct
   302401 cctcggaagc gccctgtcac gcctgacgca cgaccatatt cgcggccgcg gcctgcgctt
   302461 gggcgtgctt atcttcgcgc tggccagcgg agcgtttctg atcgtgcggt agacggagca
   302521 ggactcttgc ggtcaggccg tgaagccgcg gtcgcaaagt tccctgagcg cgccgggaga
   302581 cagtctttcg agcgccagat ccggcaacag attgttgtcg gcggcaaggt cgcggctcat
   302641 cgcggccgaa aacaggctcg ttcccgcctc atggagaatt gccggatggc cggcgatccg
   302701 cccgagcaga ctggtaggaa cgagcccgaa aggcacgtcc tcatagatgt atcggctgtc
   302761 ggccgtagcc gggccgaagc cgccccggcc ttcgaggtgc atctgctggt tcatctccga
   302821 gaccgaaccg atcggcacat ggaaggacaa ggagaagtgc tcgcgcacgg tccgtaccga
   302881 cagtccgaag ctttcggcga ttttgagccg ctccgcgtcg agcgcttcga tcagctgccc
   302941 gacggccggg gtcacgtgct cgccctgccc ccatttctcg cccttctcca tccgcgtcag
   303001 gttgagtagc gcgatgccaa gatggttttg cgggttgaga ttggaaagcg cgatcgccag
   303061 aagcccgtcg cgctcgacga atcggtcgcc gaaaagctcg ctgcagagcg ccttgccctc
   303121 ggccgcagca gctttcggca gggtggcgac atcgaccttc tgacggaccg tgttgacgga
   303181 tacgcttacg ccatccggct gctggcggcc ggtcagaagc gttgtacccc agacgatgat
   303241 cggcagcgaa acgccgcgct cggcgagcct ctttgagaga taaagcgcgc cgaatgagct
   303301 gtgcgaactg acgatgacgg gctggcccgg cttcaggtgc ggcagcgccg catcgaatgc
   303361 cattcgatgg ccgttcgccg gcagagcaat gacgaccgca tcgacatcgg cgaccgcctc
   303421 gcggccatcg cgagctatcg caaccgggcc ggaaaactcg acggcgcccg tcgcggtcag
   303481 cggctctccc tcggccagtt tacgcgtgcg cgcacccgag ggagaccaaa ggaccgggtg
   303541 atgacccgct tccgcgagga aagccgccat gccgaaggcg atcgccccgg cgccgagaat
   303601 accaatacgc atcgttgtcg ttcttccttt cgtccatcgg gccagaatcc gggcgcctca
   303661 aaccacatat ttttcaatgc ctatcaccga aaagaaaaat tgtcctttgt cactggcgct
   303721 caagatacgt tttatgcagt atgacagagt tatgatgcaa tgggcgcatg atcatcatgg
   303781 agatacggga gctcgaggcg tttcttgcag tgatgtcggc aggcagcatc actggcgccg
   303841 cccggctgct cgatcgttcc cagtcccagg tcacgcgcct catccaggat cttgagactt
   303901 ccgtcggatt ctcgctcttc gatcgcaacg gcccgaagat cgctcccagc gaaaaaggga
   303961 tagcattcca cgcggaagcc gaacgcttcc tcagcggcat cggccatttg cgggagcggg
   304021 caaggacgat cgccgaaaag gagccgcagc cgatcgagat cgtagcgatc gcggctttcg
   304081 cgagcggcat catccccatg gcgctggcgg cgttgccgga aaggctcttg ccgcgaaagg
   304141 tccatctgcg cagcctgccg gcagaggcag cggttcaatc tgttctggcc cgcacggcgg
   304201 atttctgcgt cacgtcgctg ccggccgacc agccagggct ggaggtacac ggtgtatttc
   304261 aggcaccttg cgtcgccgcg gtggcgccgg acgaccccct cactgcccgc gaggtgattt
   304321 cgatcgccga ccttgccgga cgcaatatca ttacgatggc caatccgttc cggctgcgaa
   304381 gccgcgtaga caaggctctg gaggcggcca acatccgccc ggccaggatc atcgcgacca
   304441 gcgtttcggt caatgcggta aggattgcgt cgacggggct cggcgttgcg atcgtcgagc
   304501 ccgcgacggc ctatggcttg aagctgaccg acgtcacgat ccggccgctc gacgtcgaca
   304561 tccccttcct ttgggcgatc ctttccgccg ctgcacgccc gttgtccgac agctcgcgcg
   304621 aactgattca ggcgatcatc cgggtctctt cagcctgtat accgggattt acagctcacg
   304681 acccgcgcca cgccaatcgc gctgctgaaa tgatgttggg agaagaccag acagatcgag
   304741 acgcgcgctg gcgcgactat ccgttgcata acaacaaaac gcagaaccaa aagaggagaa
   304801 tgacatgaaa gacttcatcg caagccgccg ttccacgctg aagcttctgg ctgccgggac
   304861 cggcgtactg gcagcgccgg cgatcatccg cccggcattc gcccagtcca aggtcgtgaa
   304921 catcaccacc tatgacaagt tcgttccgca gtccttcatc gacgcgttcc agaaggagac
   304981 ggggatcgaa gtgcgcattc gcctcaccga cgaccagggc aagcagtata acgtgctctc
   305041 cgccgaaggc gcgacgcctt catcggacat cgtcacggtc accggtcacc gcctgtcgca
   305101 gttcatcggc tccaacctgc tttcgccgct cgacaccggc cggctgaaga actggggcaa
   305161 tctcgctccc gcatacaagg gcgcaccgca gctgaccgtc gacggttcgg tctacggggt
   305221 gccgctgctt gccggtttcg aaggccttgc ccgcaatacg gactatacca aggcctccga
   305281 cagctgggcc atcatgttcg acaaggaata caagggcctg acgtcttata tcatttccga
   305341 tttcctccag atcaccatgc gctatcaggg taatgacggc gacttcgtca catatgaagg
   305401 caagccggag gaggcgcagg ccgcaaccaa caaggcacgc gactacctga tccagaacaa
   305461 ggacatggtc cgcaagtact acgacgccgg ctccgaggtg cagcagatgt tcgtcaacga
   305521 ggacatctat gtcgcccaca gctggtccgg ccccgcggca aagctgatca tggacggaca
   305581 tccgatcgag atatcggttc cgaaggaggg gacctatggc ttcctctact ccttcaacgt
   305641 ggtgaagaac ggaccgaata cggatgcggc ttatacattc ctcgacgcca tcctctcctc
   305701 tccggaaatc ggggcagcga tgagccgtca gtcgggcttc gcctccgcat tcggcggcgt
   305761 ggacaaggtg ctgaacgaca aggagcgtgc tgccatggcc ctgccgcagg aacagaccga
   305821 gcgcatccag ttcttcagct ccgtcaaccg cgacatgaaa aacgagatgg tcgacaaggc
   305881 agtcgccgag atcaaggcag cctgacccat cgtctcggac ccgaaggaca cggccggcgc
   305941 cactgcatgt ttccttgcgt cgaatccgat gcaggaacaa agacatgcgg caggcgacgg
   306001 ccgtgaaaag gagcttcttt tgagcctgga accacaatgg tagatacgac gacaatacgc
   306061 acccgaaccg ccgaacccct gcgggtgccc cgatatgccg gctggatcgg caagaccgtc
   306121 ggttcgggtc tctatcgcca taccatcggc cggcttgccg acagccgccc tgttcgcctg
   306181 gcgctgcttg ccggcgtccc cctcttctgg atcgcagcgc tgcacatcgg cccaatcttc
   306241 cagatggggc ggatcagctt catggcagac tatccgccat cgccggatgg aggctccgcc
   306301 tacacgctgg ccaattacaa gctgttcttc tccgaccagc tatacttcgt gcccttcctc
   306361 cgcagcctcg tcttcgcggc agtcgtcacg ctctcgacgc tggtggtcgt ctatccggtc
   306421 gcatattatg tcgcgaagat cgtccagccg aagaaccgtg tgcgtgccct gctgcttctc
   306481 ttgattccgt tctgggcggg agagctcatc cgcacctttt cggtcatcat gctcctggcc
   306541 aatcgcggcg cggtcaacgt cgcgctgcgc gaactcggct tcatcgatcg gcccatcccg
   306601 atgctctaca cctccttctc tctgagcttc ggcgtcatct atctgctggc actctatatg
   306661 ctgctgccgc tctattcggc gatcgagaag ataccgacgc agctcgttca cgcggcggcc
   306721 gacctcgggg ccagcccctt tcagcgcttc cgccgcgtga tcctgccgct gtcgaaggac
   306781 ggcatcgtct ctggctgcag tctcgtatac ctgacctcgg tcggcgtttt tgcggcaccg
   306841 ctcctgcttg gcggcccgaa taccgtcatt ttccccgagg tgatcgcgac cctctttcac
   306901 tcctcgaacg acaaatggcc cgaaggcgcc gccttctcca tgctgctgct cgcggtttcg
   306961 ctaaccaccg tcggcctgtt catgcgggtg atcggcggcc ggtccgtccg gctgatgtga
   307021 ggaggtaatg atgcgaccct atttcgccga tctccccaag accgcgctcg gcgctgccta
   307081 ctggctgttt gcggtctatc tcctgctacc tttggcgctg atgaccgcca tgagcttcaa
   307141 ggatgcgagc ttcatcgcct ttccgatcac ggactggacg ctcaactggt atgcccaggt
   307201 gcttcaggac aagcagttca tcgaggcctc gctctattcg atcgggatcg cgctggccac
   307261 gaccgctgcg gcaaccgtca taggcgtctg gattgcgctt ctggtcacga cagaaggcat
   307321 atggggcaag gcgatcatct tcgcgctcgc atgcctgccc gcagtcgttc ctggcctcat
   307381 caacgccatc tccatgcgga tcttcatccg caccgttgac atcccgaccg gcacgacggc
   307441 gatcatcctg tcgcattccg tccacgcggt gcctttcgtg gtcatcatgg tgctcacgcg
   307501 actgcggtcc atgccggcca atctggtcga cgccgctcgc gacctcggtg ccgatccctt
   307561 cgtggccttt ctcagggtca cgatccccta cctgatgccg gcgctcctcg gcggcatgat
   307621 cttctgtgtg ctcaccagca tagacgattt cgtccgtacc ttctttctcg gcggctacaa
   307681 gcccacgctg cctatgctca tcttcgcaaa ggtacagggc ggcatgtcgc cggaaatcaa
   307741 tgccatggca acgatcgtgc tgatcgtgac cgccgctgtc ggcctctatg ccgagcgcct
   307801 cacccgccgt tcaagggact gacgatgcag cctgtggtcc aattcgaaaa cgtcaacaaa
   307861 tattatggcg ccctgcccgc ggtcgatggg ctgaacctcg ccatagaacc cggccagttc
   307921 gtgacgctgc tcggcccttc cgggtgcggt aagtcgacca cgctcaggat gctcggcggt
   307981 ttcgagcagc cctcctcagg cgagatctat ctcgagggca aggcaatctc gcatctgccg
   308041 ccgaacaggc gcaacgtcaa catcgtcttc caggactatg ctctctttcc gcatctcaat
   308101 gtcggccgca acatcgcctt cggactggaa ctgaagggac tgtcttccga cgccatccac
   308161 aagcggacga tggaactgct cgccctcgtc aagctcgagg atttcgccgg ccgcatgccc
   308221 gaccagcttt cgggcggtca aaggcagcgt gttgctctga tgcgcgctct tgctcccgac
   308281 ccgaacgtgc ttctgctaga cgaacccctg tcggcgctcg acgccaagct gcgccagcag
   308341 atgcagatcg aactgaagac cattcagcga accaccggca agaccttcat cttcgtgact
   308401 catgatcagg aggaagcgct gaccatgtcc gacgtcatcg tggtgatgaa taaaggccgg
   308461 atcgagcaga tgggggaccc caacgagctc tactcgcggc cacgcagccg cttcgtcgcc
   308521 aatttcatcg gccagagcaa tttcctcgaa ggcaaggcac tctcggtaga tggtacggtc
   308581 gcaacgatcg actggaacgg aaccgctatc cgcgccgatg tcaacggaac gcagcctgcc
   308641 aaggatagcc cgacgaccgt cgcgctgcgt ccagaggcac tctactgcct ggcggagcag
   308701 ccgcaggacc gattcgcctt gaaaggccgt atcgtccagc gcgtcttcaa gggcgcccat
   308761 accgcgctca ccgtcgatct cgaaaacgga gcgcagctcc acctgcagct cgaccccgtg
   308821 gcgctgtcgc acatcgggac ggacgagatt tgggtgggct ggcgcgagcg tgatgcggtg
   308881 gttctggccg actgacacct gattagagcg gatcattttg aggggcggcg gcgaaggcgg
   308941 ccccaaaacg gaatttctgg agcaaagact attatggcga acgaacggaa cgtgcggctc
   309001 gcggaactga atgcgagggt caaacaggac ctcgactatc tgaattatcc tgccgccaac
   309061 tggtcgaagc cggtcacgat ggctgatggc cagcccgtaa gcgacgtcgt cattatcggc
   309121 ggcggaatgt gcggtatggt cgcatggctg gccctgaccc gcgccggcat tgccaacctc
   309181 cggattgtcg accgggcccg aaagggccag gaaggcccct gggtcacctt tgcccgcatg
   309241 gaaaccctgc gctcgccgaa gaacctcctt ggtcccgcgc tcggcatcgc ctcgctcacc
   309301 ttccgggcct ggtatacggc gctccatggc gaagcggcgt gggaaacgct gttccgcatt
   309361 ccccgaccga tgtggatgga ttacctgaac tggtaccgcg aggtcctttc cattcccgtc
   309421 gagaacgaca cggatgtcac ccgtatccgc ccacgcgatg acgggctcgt cgaattggag
   309481 atcgccggcg gcaaccagcc ttccatcatc acccgcaagc tggtcatggc gaccggccgc
   309541 gagggcctgg gcgagccggt cattccggat ttcgtcaagg gcatgaaacg ccacacgtcc
   309601 tgggcgcatt ccgccgaccc catcgatttc gacgcgctca agggcaaacg cgtcgtcgtc
   309661 atcggcgtcg gcgcttccgc cgtcgacaac gcggccgaag cgcttgagtc cggtgcaggc
   309721 gaggtacgcc tgctcgcgcg ccgcaaggag atgccgacta tcaacaagct gatgggcatc
   309781 gggtcatacg gggtgacagc cggcttcgcc aggatcgacc cggagtggcg ctggcggatc
   309841 atggactatt cggtaaagca gcagacgccg gctccccaca attcgaccct gcgcgtcagc
   309901 cgccacccca acgctttctt tcatttcgac tgctcgatcc gttcgatgcg cgaggaaggc
   309961 ggcgaggtgg tgctcaccac gaccaagggc cgcgtcttcc ggaccgactt cgtcatcctc
   310021 ggaaccggct tcacggtcga cccgctcagc cgcgatgagc tcgcgcccta tcaggacagg
   310081 atcgcctgct gggaagaccg ctacacgccc ccggcgggcg aggagaatgc cggcctcgga
   310141 cgcttcccct ggctcgatga cgatttctcc ttcacggaga aggagcccgg caccgcgccc
   310201 tggctcaagg acattcactg cttcaactac ggcgcctcga tcagcatcgg caaggtgagc
   310261 ggcgatattc cggcgatcag cgagggcgcg ctctggcttg cgcgcgggat cgccgcctcg
   310321 ctcttcatcc gcgacgtcga ttaccactgg gaagcgctgc tcgcctacga aaagccggaa
   310381 ctcgatggtt cggagtggac ggatgctgat gccccgcagc ccacgcaccg aaccgcctga
   310441 ttttttcgtc gagtattgcc aaacggaagg attgccatga ccgtttccac gaaagtcgat
   310501 gtgatcgacg cagttctcgg cctggattcg tcctcgcccg ttcatgcgct gcgcgagcgg
   310561 cgcgccaagc tcaagcattt cacgcagaca agctatgaag ccgcctttac cccctcggat
   310621 ccgggaaact tttcttttgc catgcgggcg gccctggcgg cgcgcatggc tggcctttgg
   310681 agatcggctg agctccaggc gcactacaag gagctgctgg aagagagggg atcgacaccc
   310741 ggcctccagg cgattgccga tccgggtgta gtacccgagg gcgacgaacg gctcgcaacg
   310801 atccttgcac atgtggacct ggtgacgctc aagcccaggg aagcgacgcg cgcgaacatc
   310861 gaagcgctct acgccgtcgg gctcgacgac cgcgatatcg tgaccctcgc aggtctcatc
   310921 gccttcgtga actatcaggt gctggtcgtg gccggtgtta aaatgctgag ggacaactga
   310981 catgtcggag gccgtacacg aattcaccct cgaaccgctc gactggcaac cctatgtcag
   311041 gcccgtgaag ctcgacgagg caacgaccga acagctcgaa gccctgaagg tgacaccctc
   311101 caacaccaag gtttcgaatt atgtcctggt gctggccaat gaagcggaga tgctcgccga
   311161 gcgcacgccg cttttcaacg acatcatgta cagcgaaggc ggcctgtcgc gtgggggccg
   311221 cgaaattggc gccctggcgg cctccttcgt caaccgctgc atctactgcg cctcggtgca
   311281 tgccaaccgc tatatccagc tcgaaaagcg cccggaagtg gtcgacgaga tctacaggcg
   311341 cggactagac gcggatctgc cggatttcga gcaggcactg ttcaatttcg gcgccgacct
   311401 gaccgcgcat ccggacaatg tcggcgtcta ccagttctac catcttcgcg aaatcggcct
   311461 cgacgatctg gagatcctcg acctgatcca ttcgatcgcg attttcggct gggcgaaccg
   311521 cctgatgcat acgctgggcg aaccccacct gaaggcgtga gatcacgcct tcaatcgccc
   311581 ggcgacagac cgggccgagg ccggaacgcg cgcacttcat cccgctctaa ccggcggctc
   311641 gtgagagtga ggctatggct gcatccacgg catcgccgag gcgctcgacg atctggtcga
   311701 catcttcacg ggtaaggata aagggcgggg ccaggagaac gtggtccccc cgctgcccgt
   311761 cgatcgtgcc gcccatcgga taaaccatca gacctcgtgc catggcttcc ttcttgatcc
   311821 gtccattgag cttcagtccg gggtcgaatg gaaatttcac cgccctgtcg gcgacaagct
   311881 cgatggcacg gaagagacct cggcctcgga tgtcgccgac atggtggtgg ttgccgagcc
   311941 gctcgacgag gcatgtctca agatagtcgc ccatcgtgac gacgttctgg agcaacccgt
   312001 cccggcggat gatctcctgg acggcgaggc ctgccgccgc agccatcgga tgcgccatat
   312061 aggtgtgccc atgctggaag aagccggatc cttcggcgaa agcctggaaa attgcggacg
   312121 acagcaacac agcgccgacc ggctgataac cgccgccgag gcccttggcg atggtcatga
   312181 gatccggaac gacgccgtcc tgctcgcagg catgcagcgt gccggtgcgc cccatgccgc
   312241 acatgacctc gtcaaggatc agcaggacgc cgtatttgtc gcagatcgcc cggacgcgct
   312301 tcagatagtc ggcgaccggc ggcactgctc ctgcggtcgc gcccacgacg gtttcggcga
   312361 cgaacgcgat cacctgatcg gcaccgagct ccaggatctt cgcttccagc tgtcccgccg
   312421 cacgcgcggc ataatccgcg tcgctttcgc cgctttgctg cagcctgtag gcaaagcacg
   312481 gatcgatatg gtgggtttcg acgagcagcg gccggaattg agcacgccgc cattcgttgc
   312541 ccccggcggc caatgcgcca agagtattgc cgtgatagct ctgacgtcgg gcaatgatat
   312601 gccggcgctg cggctcgccc ttctccacga aatactgccg cgccatcttc aatgccgctt
   312661 cgatggcttc cgatccgccg ctcaccagat agacatgatc gagcccatcg ggcgcatcgg
   312721 cgacgagccg gtcggcaagc cgttccgcgg cctccgtggt aaagaagccg gtatgcgcat
   312781 aggccatgcg gtcgagctgc gcatggagcg ctgcaagcac atcgggatgg gcgtggccga
   312841 ggcaggagac ggccgctccg ccggacgcat cgatataggc cctgccttcg gcgtcgaaga
   312901 gccggacgcc ttcgccacgg acggcgacgg gcagcttcgc atgaatggca cggtgtagaa
   312961 gatgggtcat gacgctctct tggagttgcg ggtttggagg tgggtatcga gtgcggccag
   313021 ttgcccgtcg aagcgtttca gcgcttggag cgccgcttcg ccgccccgcc cggcgacgag
   313081 ggcgccgagc acttcggcga tcgcgaaggc aggcgtcatg gcgtgcagga aggaggggct
   313141 ttcggtcggc acgatgatta tcgcttcggc gatctgcgca agcggggcca cttcgctgtc
   313201 cgtcactgcg acgatgggaa cgccgctggc ccgggcgtat tcggcaagtt cgatcgtcgc
   313261 ccgtgtatag ggcagaacgc tggcaacgag cagaacgtct gcggcccccg cacgcccgat
   313321 ggcatctgcg ccggttccgg cgatgccgtc gaggatcacc gacttttctc cgaccagcga
   313381 gagaatatag tggacctgcc aggcgaccgc atggctggag cgtaacccga ggcagtagac
   313441 ccgccgggct cccgcaagcc gcgttgcagc ctccacgata cggtcgagcg acgccggctc
   313501 cgaaagccgt gaaatctgct ttccgatcga gcccagcata tcggccgcaa gcgcatgatc
   313561 acccttgagc ttttggctcc gtgcctgctc gccggccctt tcggcgaagc cgctgtcgcc
   313621 ctcccggagg gcttcggcat agcggtcacg gagttcgtca tagccgtcga agccgagatg
   313681 tttggcaagg cgcgtcatcg acgcgggctg cacccccgcc cggcgcgcct gttcgcgcat
   313741 ggagagaaga gccacctcgc ggggatggtc gacgacatag cgcgccgccg tctgcaactg
   313801 cgtggaaagg ccgtcaaagg cggtgatgat cctgtcgctg agcggtccct tgtccatgcc
   313861 tcattctaca acgcgacatg gcgattgcaa catatgtttc agtatgcaag attatgaatc
   313921 atctaaatca aatcctcggg gtatgcgatg tccgtcgacg ctttgcaagg ggtctcgatc
   313981 acggtcgcgc ccaacggggg gcgccggacg aaggccgatc atcccgccat tccgctgaca
   314041 ccggaggagc ttgcgcggac tgcgcgcgac tgcctggaag ccggcgccgc gatgattcat
   314101 gtgcatgtgc gtaaggcgga cggaagccat cttctcgatg cggaggccta tcgtgccgcc
   314161 ataaccgcga tccgcaaggc tgtaggcaag cggttggtga tccagatgac cagcgaggcg
   314221 ctgggcatct attcgccggc cgaacagatt gcagtcgtga ggtcggttcg cccccaggcc
   314281 gcttcgcttg cgctcaggga gctggtgccg gacgaggcgc acgaggcggc ttttgccgat
   314341 ctcctgtcct gggcggcgcg gcaggaggtc atgccgcaga tcattctcta cagtcctgag
   314401 gaagcggtac gtctggccga catgcgccgc cggggcctgc tctcccgcga cgacattccg
   314461 gtgctctatg tgcttggccg ctacacgccg ggacagacgt cccttcctcg tgacctgctg
   314521 acctttctgg cgccggagat gcccgttttc gcccactgga gtgtatgcgc gttcggccgc
   314581 catgaagcgg cctgcgtaac cgccgcggcg ctcgccggcg gacatgtccg cgtcggtttc
   314641 gagaacaatc tccggcttcc ggacggcacg ccctccggtt cgaacgcgga tctcgttcgc
   314701 gccgttacgg cagtacttcg ccccctttcg attccgttga tcgacgggcc ggcgcttgcg
   314761 gacatgctct cccgcatcgg cgccgcgggc atgcacagag actgattcct tcattccgtg
   314821 gcccgtagcc ggaaccggtt aacgccggtt tcgttctccc attatcagag caattccagg
   314881 aagtctgtgt agcggtttcc ctccgggatt gcggaagcaa gaacatttcc gctgttcgga
   314941 gaaaaggcgg gaatgtccgg gagagcatca tggtgaccca tgacaacagc aacatgcccg
   315001 aaaggcgcgc cacccccgca tttccgatag gcctcatact gctggcgatc tgcgccatct
   315061 tcgcctacct ggcgattggc ggagcactgc tggaaagcga aacggaaacg gtcgtctaca
   315121 cgccaccggc cgcagacgcg cctgagcctc gttgaaggga gaccctcaat gatacccgac
   315181 ccaatcggcc ccggccccgg gccggggata attccgccga atccggttcc tccgctcggc
   315241 attccagacc cgccaccgaa cgagccgcaa cccgacaaag gccccgacga cgagccgcag
   315301 aagccgccgg acgaggagga ggaacaggcg gcggcacgcg ttctgcgcga agcttgactc
   315361 ttgccgatcg gaatgagaac atacagtgaa cattctggag attctctcat gacgcatgca
   315421 gaggaagtca tcgaacgagc catggccgcg gtcgctcaag cgcgacgtcg ccgggagcgc
   315481 gagcaggaat ggcgcaggca gactttcgga cgaattcagg tcggcatgcc gctcccgccc
   315541 ttgaagcgcg gtggcgtgca gctttcgctg cagctcgagc gtccgaatgc acgatgacac
   315601 cggcgaccgg gacggtccgg ccgaggcgga cgaggaaatc cgtggcacgg tttccctctg
   315661 gccggttcaa gcggccgccg ctgccggccg tcgtttgggg aaaggcttga aggtcagcgc
   315721 gatcaggaaa gcaccgatgc cgatgcccca ggcgccgata tagagccaac cgtagctggc
   315781 gaaaacatcg tagatcacgc ctccggcaac cgggccgatc gccatgccga ggctgccggc
   315841 cattgccgtg ccgccgatta cggtgcccat catacgcagc gggaagtttt ctcgggcgat
   315901 caccgcgtaa agcggcatga cgcctgcata gataaagccg aacaaggcag ccactgcata
   315961 aaaagcgccg aggtcgcgca cgaagaaata ggcgagcgcg ccgaaagcct gcagcagcag
   316021 acccgatacg agaatacgct tcgcgccgta gcggtctccg aggatgccga aggcaacacg
   316081 gccgcccatc cccgccagcc cctcgaggct gtagatggaa accgcggcca tcatcgggat
   316141 accgcagctc acggcatagc tcacggtgtg gaaaatcggg cccgaatggg tggcgcagca
   316201 gaagaagttc gtcagcagca agatgacgaa ttgcggcgat cgcaaggcct ggccaagcga
   316261 catgtccggt tgtccctcgc ttgcagggcc ggcattcgga tcttccagga ccggcgggcg
   316321 acgcagcagc atcgcggctg gaatcatcgt gacggcggca atggcggcta tgatctgcag
   316381 cgatgtgcgc cagtcgtaga tcgttatcag ccagccggcc agcggagaca tggtcatggg
   316441 cgccatcccc atgccggccg ataccagcga tacggcaagg ctccgatgcg tatcgaacca
   316501 gcccgtaacg caagccatca tcggcgcgaa tatcgccgcg caggcaccgc cgacgaaaac
   316561 gccgaagatg agctgaaatg cgatgagcga ggtcacgaaa ctcgaaagag ccaggctgga
   316621 agcaaggagc gccgatccga tgagcacgac cgggcgcggc ccccagcgat ccgaggcgct
   316681 accccagacc atgcttgcga gcgccatggc aaggaaaccc acggtcatgg cgctcgagat
   316741 gccggtcacc gaccatccgg tatcgcgcga gatggggacg aggaaaaccg gcaaggaaaa
   316801 catggcaccg attgcaatac accccagcag gccgcctgca gcaacgatca cccagcgata
   316861 atgcgaactg atcattttca tgtctccgct ctggcgatcc ggcgtggcat ctttcagccc
   316921 aacgccaggc ttgccgggtc aaaacaaggc attctcccgt ctgcggctat gccgcgccta
   316981 caataggacg agcggcgtct cggtacgccg acatgggggt gaaaagattt ctgcaggata
   317041 tagcgcgtcg tgtgcaatcg agttcaggcg gatgagaggc cggtgcgccc tctcagcccg
   317101 ccatgatcga tgtatcgacg acctcgaaat catgcgtgat ggtcgccgtc tttgcgagca
   317161 tagccgacgc cgagcagtat ttttcgatgg acagggcaac cgcgcgctcg accttcttgg
   317221 cggcaaggcc acggcctttg acgatgaaat gcatgtgaat gcgggtgaaa acgcgcgggt
   317281 cctgctccgc gcggtctgcg tccaactcga cgacgcaatc ctcgattgcc tcgcggccct
   317341 tttcgaggat gtggaccacg tcgaaagccg agcaaccgcc ggtgccgatc agcaccattt
   317401 ccatggggct cggccccggt gtggggccgt ccgggccggt ggccgtgccg agcacgacct
   317461 tgtgcccgct gccggattcg ccgacgaagg tcctgccttc gacccatttg atgcgtgcct
   317521 tcatccgatt ctccctcctg aaccgcattc atcataatgc gtgtgagaca aaacgcgcac
   317581 attttccgca gagccgtccg ctcagcgcgc accccatgta tcgctcagcc gatagccctc
   317641 cggccatggg tccgaggggt ctagcatgtg ctgatgggtg ccggtgatcc agccgcgccc
   317701 cgagatttcc ggcagcaccg cggggcggcc gccgacctct gtcgtgccca ggatccggcc
   317761 ggagaaggtc gaccctatca gggataccgc cgtcagacgg tccgagagcc ccatttcgcc
   317821 gcgcgcatgc aggacggcca tgcgcgccga gagcgccgtg ccggtcggcg aacggtcgac
   317881 ctttccaggc tggatcgcga ccgccgcgcc tgcccgcaga ccttccgccg tccgttcgac
   317941 tggaccggcg aagaggcaga aggaaaaatg ccgccagtcg gggttttcag ggtggtgaaa
   318001 gccaagctgg gcgttggccg cgttggtgat cctcacgcca agccgggcga tgtcatgcgc
   318061 ctcgtcgggc ttcagagaga agcccatcgc ggcagcatcc aggacgacga agctgtcgcc
   318121 accataggcg gcgtctacgg tgagcgtacc cagaccttcg acctccagct tcgcgtccag
   318181 ccggtcggca aagctcggca ggttctgcac gaagatgcgc tcggccttgc cgtcgcggca
   318241 ctccgcacgc acacggacga ggccgccggg tgcctctagc gtgatctccg tcaccggctc
   318301 cttcatcggc aggatgccgc tgtcgagcag cacggtggaa acgcagatcg aattcgatcc
   318361 cgacatgggt ggcgtatctt ccggctccat gatgatgaag gccgcatcgg cctccgggtt
   318421 cttcggcggc accagcagat tgacgtggcg gaagacgccg ccgcgcggct cgttcaggac
   318481 gaaattgcgc agggtctggt cgcccgcgat ccagcggctc tgttcccaga tcgtatcgcc
   318541 cggcggcggc gtgacgccgc caacgatcac gtcgcccacc tctccctcgg catgggcgga
   318601 gatgacatga atggtcttgg tactacgcat cgaaaactcc tcgaatcgat aagcgagcgc
   318661 ggctgcgggt gaaaacccgc ttattatccg ccctatgaaa gccaatccgg caaacgcggc
   318721 gcaacgcgcc cggtcaaggc caccgcgacg caatcggcaa ggctgccgaa acgcaccgca
   318781 cggccggaca gcccggggcc ataatgggcg tatttgccgg aattggtcat cacggcacgg
   318841 gtacgcgcgg ggaaaaccgg ctctgaaatg gagcaccagc agagatcggg cagcacctgc
   318901 acgccgcttt cttcgagccg cgtcagcgtg ccttcgtgtt gcgcctttgc gataacttcg
   318961 tgtcccgccg tgacgatcac ggcgacatcc gggtgccgtc tgcggccgtc cagcgcatcg
   319021 gcgagcgccc gacattcggt aagggaggcg tgcgggctgc cgatggccac cagttccacc
   319081 tcctccggcc ccccattcag ggccgaccag gccgctatca tctcggcacg ctttatggcc
   319141 aggcggtcgg cgccctcggc tgccgcaccg tccgcttccg gcgtcacgcc ttcgacatgc
   319201 agcataggtg ctgccgaagt ggtgccgaag gcggcacaaa gcgccttgag gtcgtcacgc
   319261 gagggccgcg ccggagcaag cccgcacagg agtggaatgc ggtcgggcgc cgcgcgcccg
   319321 gcaagatagc cgatcagcgg ccagaaggca tcgtccacac catcgggcag ttccacgtcg
   319381 atgacccgcc gggccctgcg atgtgcgtcg agatagacgc cggagagcgg cgcgcgcccg
   319441 gtgagcgcga tgcagagatc gaggaaatcg ggatgcttcg ccgttcgcgc accgagaacg
   319501 ctgttggcga agatcaccgc attggattcc gcccaggcga tcgcttcgcc cggtaccggc
   319561 gcgctgtcga gcagataggg ggaacaggtg aaggtcggtc ggcagcccat gcggacatag
   319621 gcatcggcga gccgcgccgc gggacctccg aacgactccg gcacgccctg cgtccgccaa
   319681 ttatcgcgat cgaccgaaat ggcattcatc gtcgtcggca cccggacctt agctcccata
   319741 tcggccatct tctcggcaaa ggtcagattg gcggggctcg catagatgca gccgtcgata
   319801 tgggcctgca ccacgtccac aaggccttgc gccccctgct gcgccgccat ggccgttatg
   319861 atgcgcatgg cctgttgcac cacgaccccg tcttccccgt ccagcatgga acgatcggcc
   319921 tcggtaaggc cgagcgccgc cgtcgccggt ggaacgacgg ggagtgtcag cccctctgcc
   319981 tctatcgccg tgctgccgat ccgcgccgtc ttcgctccgg caagcgccgc aaaagcctcc
   320041 ggtccaaggc gcagcaccgg cagcggcttg ccgaacatct cgaaggcgac cagcgcgccg
   320101 agcgtcagca cgtcctccgg ttgggaaaat acgagggcag cgggaccgcg gccggtcagc
   320161 aggaggtcga gcagcacgcc cgaacccgtg caggagccgc ggctcgaggg catcatcagg
   320221 atggcaccgg tgagcgagac gccatgctgc gggtggtgca cgtcgatcac gcagccggta
   320281 tcgggatcga ccccgcccca gaagctcagg gcctccgcca tatggatgac gggaccttcg
   320341 gccgaaccct gaaggatgct gcgggcgcgc tcgagggcgc tcattttacg acgaagccat
   320401 gggcgaaggg gtcgcggtca tcgataaaaa tggtgttgat gccggtcatc cttgcccagc
   320461 cggcaatcga tgggatgatc gcatcgcgat ccgcgacctt cgcggccgcc tcgacgcgtc
   320521 ccttgaagag cgatccgatg atcgactcgt gaacgaattc gtcgcccacc ttcagctttc
   320581 ccttggcggc gagctgcgcc atgcgggccg aggtgcccgt tccgcagggc gagcgatcga
   320641 tggccttctc gccgtagaac accgcgttgc gggcgtgtgc ctcggattgc gtcggctttc
   320701 cggtccactg gatatggctc aagccccgga tctccgggtg ctcgggatgg acgaactcgt
   320761 atttttcgtt cagcgcggca cgcagcttcg ggctccagcc caccagttcc cccgccgtat
   320821 gatcggccat gtcgcggaag tttttctgcg gctcgacgat ggcgtagaaa ttgccgccat
   320881 aggcaacgtc caccacgatt tcgcccaggc cctcgacctc ggccgtcagc ccttcggcat
   320941 aaaggaagcc gggaacattg gtgaggcgca cttcctcgac gaagcggcct tcctggcggt
   321001 aggtgatgtc caccttgccg gcgggggcat cgatggagag cctgccgggc tcacgcggtg
   321061 tgatcaggcc gttctcgatc cccatggtga tggtgccgat ggtaccatgg ccgcacatgg
   321121 gcaggcagcc ggaggtctcg atgaagagca ccgcgacgtc gcaatcgggc cgcgtcggcg
   321181 gatagagaat ggagcccgac atcatgtcgt gaccgcgcgg ctcaaacatg aggccggtgc
   321241 ggatccagtc gaattccttg aggaaatgcg cgcgcttttc cagcatgttc gcgccttcca
   321301 ggcgcggccc cccgccagag acgaggcgga cgggatttcc gcaggtgtgg ccgtctatgc
   321361 aggagaaggt gtgggtggcc atgatcgaaa cctctgtcag aagcgttgcg gcgaaaagga
   321421 tgcaatgtcg atggccggtt gccggccggt caggagatcg gcgacgatcc ttgcggtgcc
   321481 cgccgattgg gtcaatccga gatggccgtg gccgaaagcg tagacaaccc gaggcgtagc
   321541 gacggcgcgg ccgatcgcgg gcaggctgtc gggcagcgag gggcggaagc ccatccactg
   321601 taccccgcct tccggcttca gccccggcag gaagccctgc gctttcttca gcatcgcttc
   321661 cgatcggtgg aagttcggcg gtagatcgag ccccccgagt tcgaccgcgc caccgacgcg
   321721 aatgccggtc gacagccggg tcaccacgaa accatggccc ccgaaggtga tctgagtacg
   321781 caggtcgaaa gcgccggcgg ggagcgtcgt attgtagccg cgttcggttt cgagcggaat
   321841 gctctcgccg atagtccggg cgatccggtg cgagaaagcg ccggccgata gcaccacctg
   321901 tgccgcccgc tgaatctcgc cgtcggtggt caggacgtcc actccgccgt ctaccggcct
   321961 cagggccgta acctccgctc gctggacttt cccgccgatc gtccggaagt gatcggccag
   322021 cgcaagcgta tagagcttcg gatcggcgat cgagtaccag ccgggtgtga aggtgccatg
   322081 ggtgaagcgg gcggcaaggc ccggctggat cccgctcatc gcagcagcgt cgagatgatg
   322141 gaactcgata ccgtgatcct cccgcgcctt ccacccggca agcgaggcct tgaattccgc
   322201 ctcgccctca tagacctgga ggttgccctc cttgcgcagc atggacgccg ttccggtttc
   322261 cttgagaaag ggttcgagtt ccgccttcga aaggtccatc agcgctgtct gcgccgcggt
   322321 cgaatgcgcc acgcgtcccg gctgacacgc gcgccagaag cggaacatcc atggcgcgat
   322381 cttcagcgcg taggcgggcg gcactgtcag gggcccaagc ggatccagga gccatttcgg
   322441 cgcttttctc aggatgcccg gcgaagcgag cggcaatata tcggtgaagg cgaaggcccc
   322501 ggcattgccc gcggaggccc cggccgccgg accctcgcgg tccagcacgg tgacggacag
   322561 gccgcggcca acggcggcaa ttgcagccga aaggcctacg accccggcac cgataacaat
   322621 gacgtccggt tcggccatct aacgcacgct cgccagaaac ttttgcgtct cggcgttttg
   322681 cggcatcgcg aagatctggt caggcgtgcc gatctcggcc atgaccccct gatggaaaaa
   322741 cgccacgcga tccgacacat cgcgggcgaa ggccatttca tgcgtgacgc agatcatcgt
   322801 cattccctct tccgcgagca tcttcagcgt gtcgagcacc tcgccgacca gcatcgggtc
   322861 gagagccgag gtcacttcgt cgaacagcat atattccggc gacatggcga gcgcccgggc
   322921 aatcgccatg cgctgctgct ggccgcccga catgcggttc ggatagacct tgagtttctc
   322981 ggccaagccc acatgggtca actgctttac cgcgatctcc tcggccttgt ccttcgccag
   323041 gccaagcacc tttctcgggg cgagcatgac gttttcgagc accgtcagat gcgggaatgc
   323101 gttccactgc tgaaacacga tccccacttt gcggcgcagc ttgttgagat cggtgccctt
   323161 ggcgtggaca tcggttccgt cgatccggat cctgccggag tcgatcggct ccaggccgtt
   323221 gatgcaggtg agcagtgtcg atttcccaga accggagccg ccgatgatgg tgaccacttc
   323281 gcccttgtcg acagtgaggt tgatgccctt gagaacctcc agcgaactga acgatttacg
   323341 gacgttttcg atctcaatca ttgggggacc accgtttttc gagatacccg ccaaaccggg
   323401 cgacggggaa gctgaggagg aagtagatgg cgccgcagat cagcaggatg aagagcggct
   323461 cctgcagccg ggtgacgaga atctgcgaag cgcgcagaag ctcgaccaga ccgagccaga
   323521 gcaccaaagc ggaatccttc atcacgccca gcgtcaggcc gatccacgac ggaagcgata
   323581 cccgggttgc aagcggcgcc acgatatagc gcatatcctg ccaccaggtc atgccgaggg
   323641 agcgcgccgc acggcgggtc gtcaccggca cggaggaaat gccgccgcgc acgatctcag
   323701 cacaaaatgc cgccgtatag agcgacaaca ccacgccgga ggtggtgaag gcaccccagc
   323761 caagctttac gatggactga aacgcactgc cgagcacgag ctggatcagc agcggcaccg
   323821 agcggaacac gtcgagcagc aaagtcagcg gcgcggccca gtagggcccg agctggaatc
   323881 gtatcactcc aaaaagaatg ccgagcaggg tgccggcggt aacggccacg gcggttaccg
   323941 caagcgtcat ccctgcgcct tgcgcaagga aggcgagatc gttccaggtg agcgcagtat
   324001 taaacatctc tcacctctca gtaacggaac atgcgccagg cgaaagcccg ggcagcgagc
   324061 gtgacggcct tggcgatcag gtaatagatc accgcggcga gcgcgaagaa ttcgaaggtt
   324121 cggaaggagc gggcattcag ctcctgcgtg attccggcga gatcggtgtt catgccgacg
   324181 gtgacgccga gcgacgtcat caggatcgcc cagaccatct ggttggtcgc aggcaggaaa
   324241 gcgacgcgca gcatctgcgg cagaacgatc agtcggaatg cctgcaggga ggtcatgccg
   324301 agcgaccggc cggcgcgggc ctgcgtgtcc ggaatggcct tcaacgcacc acggaaattc
   324361 tcggccagat agccggcatt gttgaaagcg atcccgacca ggagtgccgt gtaggggctc
   324421 aggtgaatgc cgaaattgcc gaggccgaaa tgggccatgt agatctggaa cagcgccggc
   324481 gtgttccgcg cgacctcgac ccaggtcgtg gcgatgccgc ctaggatacg gctgccggac
   324541 aggcggaaca ccgtgagcgc gattgcgcag gcgacgccga tgaccatcga cagcaccgcg
   324601 acctgcagcg tcaccaccgc gccgtcgagc atctgcggca gtgccctcag cgcctggttc
   324661 caatggaagg tgtaattgaa cattcccgtc tcacccctcg gaatgcagcg acggtgcggg
   324721 ttgccccgca ccgtcagacg atcctcggat cagcggtaaa cgccgttcac cgcgagcgac
   324781 ggagcctcgc caccgaccca cttctcgtag agttcggcat agcggccggt gcggacctgc
   324841 tgattaacga acaggttgag gtaattgatg aagccgtatt cctcacgatt ggtgaagagg
   324901 gccacgtaat cgatatcgaa gggcgccttg tcgaccacgg agataccggg aaacttgccg
   324961 cccttgacgt tggactgcgc gacggtcgaa gtggagacgg tggcgtcgag ctggccctgg
   325021 ctcagcgcca ggaagacgtc ggcctgcgtc tgataggggc ggaactcgcc ctcgccccag
   325081 gccttgacct ggttttcaag tgcgatggct tcataggtgc cggcggtggc gccgacgacc
   325141 ttgcccttca tgtcttcgaa ggacttgatc ccggacttct cgttggcggt taccgccatt
   325201 tcgaaggcga agtagggaac ggtcatgcct acggtcttgg cacgctcaag cgtatcggag
   325261 gtggaagcga caccgacgtc gacacggccg gacatcagcg ccgggatacg ctcgggaaac
   325321 ggcgtctcga cgatctcggc agtgacgccg agcgccttgg ccagatcgtt gcaataatcc
   325381 acgtcgaagc cgatcggctc gttgttctcg tcgcgcgagc ccatcggcgg gaaatcgagc
   325441 accacggcgc aacgcagcgt tccggaagcg atgatgtcgt ccagcttgtc ggcatgagcg
   325501 gggctcgtca gagcggtggc ggcaacgagg ccgaaggcga ggatcgaggt cttcattatt
   325561 gttctctccc tgagttgtca gccggtgtga cggcgcgcgc actattccgc gtcggagagc
   325621 acaaatcaat tcaaaaatac aactagtata caaaacgtat ataacgggcc gcctttcgca
   325681 atggaaaggg gctttccctt gtggaaaagc cccttttatt gcgcgaacgg caagctgaat
   325741 caggcgagga agtcctcggg cagcaggtct tccggcatgt tctggtaagc cacagggcgc
   325801 aggaaacgtc gaatcgacat cgtcccgacg ctggttgcgc caaaattggt cgaggccgga
   325861 tacgggcctc catgcaccat ggagtcgacg acttcgacgc ctgtcgggaa gccgttgacc
   325921 aggacccggc cggctttccg ttcgagcacg gggcgcaacc ggcgcgcggt ttccagatcg
   325981 cccgcatcca tatgaatggt cgcggtcagc tggccggcga agccacgtgc gagctcttcc
   326041 atctcggccg gcgatccgac ccggatcacc aggccgagcg ggccgaacac ttcttcgccg
   326101 agcgcgtggt cggagaggaa ctgctcaccc gtcgtctcga agagattggg ggacgcatca
   326161 cggccggacg actcggttgc aagcagcggc tttacggcgt tgcgcgtcgc gaaccgttcc
   326221 tgaccgtcgc ggtaggcctt ggcgatcccg tcggtcagca tggtttgcgg cgccaccttg
   326281 gcaagcgcct cggcggcggt ggtggtgaag cggtccgcgt cggttccttc gatgacgaca
   326341 gctattcccg gattggtgca gaactgcccg gctcccatgg tgagcgaccc ggcccatccc
   326401 tgccccaaag cttcggcccg cgccttcaag gcttccggaa gcaggaacat cggattgacc
   326461 gagccgagct cgccgaagaa cgggatcggc tcgggacgcg cggcgcaaag atcgaacagt
   326521 gcacgtccgc cggcgagcga gccggtgaag ccgacggcct tgatattcgg atgctgaacc
   326581 agagcgtgac cgacatcgcg gctgccgccc tggattagcg agaacacgcc gggatgaacc
   326641 cccgtcttgc gaattgcggc gtcgatcgcc tcagccacga tctcaccggt gccgggatgc
   326701 gccgaatgac cctttaccac gacggggcaa cccgctgcga gcgccgccgc ggtatcgccg
   326761 ccggcggtcg aaaaagccag cgggaaattc gaggcaccga agacggcaac cgggccgacc
   326821 gggcgctgga tcaaccggat ctcctgacgt ggcgccggct ggcggtcagg cagcgcggca
   326881 tcgacgcggc gatcgagata atcacccttt tcgatatgat cggcgaaaag ccggagttgt
   326941 ccggtggtgc ggcccctttc gccattgagc cttgcctccg gcagccctgt ttcctggctg
   327001 ccgatgtcgg ttatagcttc cgcacgggcc tcgatctcgt cggcgatggc gcgcaggaag
   327061 gcggcgcgct ctttgcgcga ggaatagcca tagctccaga aagcctcttc ggcagcgtca
   327121 caggcccggt ttaccagctc cacggtgcct acggcaaaat catgcgccgg gccgtgcgcc
   327181 ggagctgaag cgaaggtgcc ggctccgtcg agccattcgc ccgcgacgag gtgttttcct
   327241 ttgggggtga aaaccatctg aacttccttt ctctgaaacg cggcgatctc gttcgattcg
   327301 gtacaagatc agaagacgcg tcgaatctgc tgcccagcgc ctcttatcag atgcgcaaag
   327361 atcgctctat gttttaaagg cgttgcatgc cttgcccttc ggtcgggtac gatcaaagga
   327421 aacatgcaga cccggcagaa aatcgcatac actcgcattt ccgcaaccgg atgcttcgga
   327481 acgcgaattg cacttgccgg agctttgtat actctatgta tgcagaacat caaccgcctg
   327541 ccctgcgtaa ggcataccac gagagagacg acatgagcga gacaaccacc ctgacgacca
   327601 ccgcgcttca cgagcgcgtc gaggcgatct tccggaaggg cggccttaac gtggtacagg
   327661 cgggcgctct cgcccgggtg atcgttgccg gcgagcggga tgcctgcaag tcgcacggta
   327721 tctaccggat cgaaggcgcg ctgcgcacgg tgaaggccgg caaggttaag ccggacgcga
   327781 taccggaaat catcgcgcag gaggcctcgg cgatcgtcaa ggtgaacgcc ggaggcggct
   327841 tcgccaatcc cgccttcgag ctcggcctgc cggtactcgc cgagcgcgct cgtacgcagg
   327901 gcatcgcggc gctcgccatc aacgactgca cgcatttttc cgcgctttgg ccggaagcgg
   327961 aggcgctcac gggagaaggg cttgccggcc tcgtcatgtg cccgagctat gcgacggtcg
   328021 cgccgaccgg cggcaacaag ccgcttcttg gcaccaatcc tttcgccttc ggctggcccc
   328081 gcgccggcag accaccctac gtcttcgact ttgcaacctc cgtcgcggcg cgcggcgaga
   328141 tcgagctgca ccgccgcgcc ggcaaggctc tgcccgacgg ctgggcgatc gatgctaagg
   328201 gcaatcccac gaccgacccc gaggccgcgc tcgcgggtgc catgctgccc ttcggcggac
   328261 acaagggctc ggctatcggt acgatgatcg aactcctggc gggaatcatg atcggcgacc
   328321 tgacgagccc cgaagtgctc gactatctcg gaaccaccac gctcgcgccg ttccacggcg
   328381 aattgatcat cgccttctcg ccggaggctt tcgccgcagg ccgaccagga gacccctttg
   328441 cccgcgccga gatgttgttc gaggcgattg tcggccaggg cgcccgcctg ccttcgcaac
   328501 gccgcttcgc tgcgcgcgcg aagtcggagg ccgaaggcat caccctgacc gcagccgaag
   328561 tcgagcaact cgatcggctc cttacgctcg ggctcgacgc cgtggcgtaa tgcaggcacg
   328621 atgaaactcc ttcctccctc gtcactgtgc ctgtaacggg gacgagggag ggccgcgtct
   328681 gcggtgcgga aatctatctc cagcccaatg acctggccga ctgaattcct gtgaaaagcg
   328741 cggaaacgca ggacaacaga catgaaccgg ctggatcggg cacgccgatg ggcaagagac
   328801 atcaagcggg acgttatcgt gctgtggctg gcggcgcgtg acagccgtgt accatggtat
   328861 gcgaaactgg cggctggggc gattgctgcc tatgcactgt ccccggtcga tctgatcccg
   328921 gacttcatcc cgatcctcgg atatctcgac gatctcgtca tcgtcccctt gggcatcatc
   328981 gcggtgctca ggctcatccc gaccgacgtt ctcgcggagc tgcgcatcga agcgctgaaa
   329041 caggtcgagc gcccggtcag cagagccggg atggctgcgg tgatatcgat ctggcttatc
   329101 tttgtagcgc tgatctcctg gatggcgctt gcaccctgaa ggggaaaggc accttggagg
   329161 cagaacggcc aaagggtggc gatcgacagt gtcggcgttg ccacgcaagc ggttccgttc
   329221 ttatactcct cgtgtcatgt acaagacatt cgtcgcagcg cgagaggacc ggcccggaga
   329281 agcttggctc tccaggtttg cggccgggcg agccgaggcg gagaggtggt atttcgggca
   329341 ggcgccaatg gcggcgagcc caagtgccaa ggagtgtcgt gccgctttga tgcagcacat
   329401 gcctgagctc gtccctcact acgaaagcgc ctgtgatctc gtcggagatg atgagatcgc
   329461 tcatcggctg ctcagccact accgtcccgc gccggagcgc tatggctgca gtcagtctgt
   329521 ctggctcgga aaggaaggcc cggcgctgat ccgcaacttc gactacccac cggatatcgt
   329581 ctctgaccgc ttcgagatga ccgattggtc tggcgtgaag gtgatcgcga agatgcagcg
   329641 gccctgggga ggttgcgtgg acgggctgaa tgaggaggga ctggccgcaa gcgtgactct
   329701 cgggggtggc cgctctcagg gtctcggctt ctcgatcatt cttgtgatgc gctatttgct
   329761 tgaaaatttt cgtgaggtcg gcgaggcggt gaaggcgctt tgccgaatac ccgtggcgct
   329821 cgcacagaat gtcacggtgc tggatcgtgc tggcagctac gcaacgctgt ttcttggtcc
   329881 ggggcagcgg ccggtcatca cgcgcctgaa ggcatgcacg aaccatcagc ggggcggaag
   329941 accctcatcg tcttctttgg cgcgacagca atttgttctg caagcactgg aagacccatc
   330001 gatgtcgctc gagaagctga ccgaccgctt tctccagccg ccgctctatt ccatgcgtct
   330061 tccccaaccg accctgtaca cggctgtcta ccgacctgcg gaagggcggg tggattacat
   330121 ctggccaggg aaccactggt cgcaaggttt cgacggcttt gagacaggcg agtacaccca
   330181 tcgctatgga tcatcgggcg gcccgctggc cgaaagtccg gcatcttaga gcatttccgc
   330241 tttctccgat ccggaaactc tccaacccct tgttttgtgc aattccggac gaaaaaccgc
   330301 tgcgcacttt tctggaattg ctcgagatcg cgatgcgtga gacgcggtat catcccgctc
   330361 cacggagaaa ggcacgcccg accggggtgc ccttctccat tctttatcgc ctgatcatgc
   330421 gcggtatttc tcgacggcgc ccggaagctt gcaccattcg gcataccagg tgttgaagag
   330481 cctgaactgc gcctcgacgt agccacgctg gctttcggtc agggcatcgg tctcgttgaa
   330541 atggagcgtg tactccttgt ctcccttcag caccatcatg tgcttgaagt agagaacgag
   330601 gtccggccct tcgtcgaagg aggaaagcac ggcaagcgcc tgctccagct cctgcgcccg
   330661 ctggcgcgca tccacatcgc ccgcagctgc cgcctgcgag agattgcaga gatggatcac
   330721 ttccttcggc aggacgttgc cgatgccggt gatggcaccg gtcgcgccgc agttcacgaa
   330781 cccatggaag acggccgtat cgacgccgat catcagcgag acgccgtcgt cgcggctggt
   330841 aatgttctcg gcggcataac gcatgtcggc gttgccgccg aactccttga acccgaccag
   330901 gttcggatgc tctgcgcgca gcgcgaagaa caggtcggcg cgggtcgcga atccgtaata
   330961 ggggctgttg tagataaccg ccggcaggtc cggcgcggca gtcaggatcg ccttgaagtg
   331021 tgccttctgg gcgacgatcg aagggccgcg cgaaagcacc cgtgggatca ccatcagccc
   331081 ctgcgcgccg accttctggg catgcgccgc atgcgcgacc gccgcggcgg tgttgacggc
   331141 cccggtgcca acgatgacgg ggatgccggc cttggtcaga cgctccacgc cttccatgcg
   331201 ctgcgcgtcg gtcaggagcg gccagtcgcc catcgaaccg caatagacga ctgccgacat
   331261 gccgtcggca atcaacgctt tgcccttgcg gaccagagcg tcgaaatcgg gcgtgcggtc
   331321 ttccttgcaa ggtgtcatca gggcggggat tacgcccgag aatatcttgg ccttcatttc
   331381 aaactcctat tggcctgacg gatggcagag acgtgagccg agatcggcgc cttcgtccgt
   331441 gcttcgacaa tgaaaatacc acttgtattt tatttgtcga caaaaatcgc tctaagctca
   331501 cagggcaatt tccagccggt ctttgcgggc gaaaagcttc tgaatctgct cgacgatctg
   331561 ctcggcgtgg gttcgcgcca gccgatccgc ggcctcgaca tcccgcgctg cgatgaccgc
   331621 gatcatgtcc tcatgctcgt cgacgaaacg ctgcggcagc cgatcgtcgt aggactggta
   331681 atagagcctg aggattcgcc gtccctcgtc gaggagcctg ttgaacaggc cagtgaaata
   331741 ggggttgcgg ccggcctcgg cgatggcgga atggaaggcg gcgttggtgg cgatcattgc
   331801 cagcgcatcc tgcgcctgaa cggctgcagc aaattccgcc tgacgggcac ggatcacctc
   331861 cagatcctcc tgacggtggt gttcggccgc cagacgcgtc gtcacacggt acatcagcac
   331921 cagtgcgtcg aagaaggtat gcaggttcag gaaatcgatg ttcgacacca tggtcgacct
   331981 gttgggcagc gtagcgatca gcccctcgcc ggccagccgc accagcgctt cgcggatcgg
   332041 cgtccgcgac atcttgaacc tctcggcaag ctgtacctcg tcaatcgggc tgccgggcgg
   332101 cagaaccaga tcgaggattt cgtcacgcag caggtcatag accatcttca cgccggaacc
   332161 gcgcttgcgc tcgggagctg aactggcgtc tgaatccttg tcggtcatgc ggcctccttc
   332221 ttgtcgacaa aagaaatact tgtacgaacc gaccagatca accgactctc ccatgtttcg
   332281 cggattcgaa taggttttac cgataaaaac tcagaatccg gcttctccga ggacatgggc
   332341 tgagaatcca gcagctggcg tttcctcagg catccggcag ggtaaaaacg gtgcagggcg
   332401 ctgcgatgcc gcgaagcgcg tgtttcccga gagacaccaa gggcgtctcg gtttctgcgg
   332461 caattgcgcc ggaaatcagc accgagcgcc cgagcggccg gcacagtcct tccagccggc
   332521 tcaccaggtt tacagccggt cctatggcgg tgaagtccag ccggtcgatc gacccgacat
   332581 taccccacaa tatctcgccg agatgcagcg ccgcaccgaa gcgaagtggc ggcagttcct
   332641 gctcctgacg caagctgccg agatgcgcca tgcccgcacg ggcggcaacg accgcgcgca
   332701 gcgcctgctc gcatgcctcc gccggcgcac ccgtaaccgg aaagattgcc agcacgccat
   332761 cgccgataaa cttgagcacc tcgccgccga acgcatgaac cgctcctgca acgcggtcga
   332821 accaggcatt gagcgccgcg atcacgcgcg ccggttcgtt ctcctcggaa agggcggtga
   332881 agttgcgcaa atcggcatag aggagggcag cgcgaatgct ctcaccagtg ccccggctga
   332941 gcgcgccggc ctgcacgcgg gcggcactgc ggcggccgag ataggcctcg agcagggctg
   333001 cgcgcgtcgc ccgctccccg aggacagcca agggcgcggc ggcaaagcgc gcaatctgac
   333061 gcagccgcgc gacttcggcg ggatcgaacg gccgcatccc ggcccagccg atgatcacct
   333121 tctccgaccg gccgacgata tcctcctgca ccggaccaag cccagccagc caatcggcgg
   333181 cactgtcgac cggcccttcg gcaaagccga gcgcctcgat gaccgccccg ttctccgccc
   333241 gccagagcca ggtgcgctgc gcgataatgg gatgccgcac cgccagcgtc agagcaccgc
   333301 ctgccagcgg cagtccgtcg gcaagcagcc gatttccaag ctctgccagg aacgcgtcgg
   333361 ggccggacga ggtgcctgcc tcatccagaa gccattcgag aggtgcgggc aggtccatgc
   333421 tgcgatcata gtgcagtttc tgaaaaagtg cgaaacggtt tccctgcaaa agcgcgtcct
   333481 ttcgaaggac ggatcgttcg gtgccacagc ccggcttgac aggcagtggc gcagcggacc
   333541 tggccgggat atcatcgacc cgttctgatc aggcgtccgg gaccttcaca gccggtgcgc
   333601 catggcaagc cgaaggggag tccgatgcaa gaaaccctcg tcgtccgccg cgagacgcat
   333661 gtctcggcgc cgcccgccgc ggttttcgcc ctgctcacgg atccggaaaa gatcctgcga
   333721 tggatgggaa cggaggccga ggtcgagccg aagccgggcg ggctctatct cgtcaatgtg
   333781 accggagctc gattcgcccg aggctccttt cgcgaggtgg tcccggtaca tcgcctggct
   333841 tacagcttcg gctgggacgg cagcgatgtc gtgccgccgg gttcgagcct ggtggagatc
   333901 gacctggtcg aagaggcgga cggaacgctg gtgcgcttga cccattcggg tcttcccgat
   333961 gcggagcaat gtgccggcca cgtggaaggc tgggcccatt acctcgatcg cttgtcagcg
   334021 gcggcggccg gacgtgatcc cgggcccgat ccgtggcacg gccgtacagg ataaggctcg
   334081 cgaaccgctg cctcttcact tcttcgcgcg gaactttgca gagcctgatg tgtttgccgg
   334141 ttgccgttcg tgcaagggcg gctcacaagg cgtcgcgagt gatgatatcg acagggaaaa
   334201 gcgctgagca acggtccgcc gctcgaacca tgccgagact cgagcgcaac ataagcgcca
   334261 tcctgaagcg gcgcgaggag gaagagcgcg ggcgccacgc gcatgacagg ctcgctcagg
   334321 cgatcacgac gtttgcggga tccatgactt tcgtctgcct gcacgtcctg gtgttcggcg
   334381 cctggatcgc agcaaatctc gggctggttc caaacgtacc ggtgttcgat ccgacctttg
   334441 caatcctcgc catgatcgct tcggtcgagg cgatcttcat ctccaccttc gttctgatca
   334501 gccagaaccg gatggccgaa aaggacgacg agcgttccga tctcaatctg cagatatcac
   334561 tccttgcaga gcaggaggcg acccagttgc tcacgctgct tcgcgagatt gccggtcggc
   334621 tgggcgtgaa ggtggacggc gaggaggata tccgtgaact ctcaaaggaa gtcacgcccg
   334681 aagagatcct caatcggctg gaagaccaga aggtccggtc gggcgaatag cttgtcgccg
   334741 cgtcaaggaa agctgcggaa gcccgccccc gaggaacaat tgccgcctgc acgctattag
   334801 atcacgatgc cgacagcgaa ggagaccgag atggaggagt cacaagctat ttcccgtccg
   334861 caacgcccgt ccgactattc tggccgccaa atggactgcg tcgccgcttt gcggccggcc
   334921 gtttcagatc ttgcggcgac gtcccaggag agcatcgtgg cggcgatgag cggggaactg
   334981 accgacgagc tgcttgcgct cgccaaacgg gcggaacggg ccggctggac gttcgatgag
   335041 gcatcggctg caatccagga acttgcgcgc gaatatgagg gcgccaaagg aacgatcttc
   335101 gactgaaccc ggttgatctg ccgacctgct tcccatgacc aggagataag ggcctttggc
   335161 gaaactcggc gttttgacct ttcaccgatg tatcaactac ggatcgttct ggcagacgcg
   335221 atgtctcgtg catggccttc ggtcgcttgg cacggacccc gtcatcctgg atcatcagtc
   335281 cacccgtgtg acacgggccg agtggcgctg cgcgatgcag ccgctcctgc ccgcgagaac
   335341 cgcacgcccg gatattccac tctacgcttc gaagatcaga aagtttcaaa gcgcgctggc
   335401 ctcattgccg accagcgcgt ccttcgcgct tgacgatcca gccggcgccg aagaatgcga
   335461 tatcctggtc gtcggcagcg acgaggtctg gaacttccgg catccctggt acggcggctg
   335521 ttcacttttt tatggggaag gtctcgccgc taagaagaaa gtttcctacg ccgcgacctt
   335581 tggaaatcac ccggcagcga acggccttga accctactgg gccgaacggc tgcggaactt
   335641 cgatgggatc tccgtgcgcg acgagaattc aagggcgatc atcgaaaagg aagtggggcg
   335701 cgaggcgata ctcgtcctcg atccgtgcct gcaattcccc gaaacgattt cctttggccc
   335761 gaatgcttcc gcttcgcgtc cctatatggc cgtctacggc cattcgtttc cctcatggtt
   335821 ccagaacgcg gtacgcctat gggccggggc gcgctcgcta ccgctggtca gcgtaggata
   335881 tcgcaatgaa tgggcggacg aacagtggct cgatgccggc ccctacgagt ttgcggcctg
   335941 gatggccggt gcggaggccg tcgcgacgaa tttctttcat ggctgcgtat tctccctgct
   336001 gaattccaag cccttcgtca cggctctctc cgactatcgc tccaacaaga tcgccgatct
   336061 tgcacgcacg gccggcgccg aacggcacgt gatgtcgcag gagacgcgac cggccgaata
   336121 cgaggcggtc ctggcagaag gcctggatcc ggccatcatt caccggcttg ccgaacttcg
   336181 tcgccaatca cggatctatc tcacagatgt cctcgcctga acgcacagca tcggcctcgg
   336241 tcagcccaat gctctcgccc cagcgaatgg tgaaatcggg cctttgcatc ggctgcggca
   336301 cgtgcatggc ggagtcgggc gacggcgctg cgatgcatct ggaccggtac ggccagctca
   336361 agccggacag atcaaataat ccggcaggat ttgccgaatt gtgccccttt tcgccccacg
   336421 cccgaagcga agatcaaatc gctctggctc gtttcggatc ggcgcgattt tacgattccc
   336481 ggatcgggcg cttcgaggct gcctatgtcg ggcatgtcct cgagggcagc ttccgagtgg
   336541 acggcagttc aggcggcatg gccagttgga cggccgcgga gcttttgaga agaaagcttg
   336601 tcgacgccgt tgcgcatgtc gttccgcgcg agggagacgg tgaacgtctg ttccgatatc
   336661 agctctcgcg gaccgcggaa gacctgcgca agggcgccaa gtcgcgctac catccggtgg
   336721 agctatccgg agtcgtcgcc gagatgaagc gccacccggg ccgctatgcg gtcgtcggca
   336781 tcccctgctt catcaaggcg ctccatctcc tgagccttca ggacccggcg ctcagggagc
   336841 gacttgcttt cacgctcggt ctcttctgcg ggcacatgaa aagcacgcgc ttcgtggaga
   336901 gtttcgcctg gcagatgggc acggacatga acgccgtcgc gggcgtcgac taccggctga
   336961 aggacccccg gagaccggcc aactggtaca ccgcccatct gcggctcaag gatggaagca
   337021 ccagaagcaa ggactggtgg catctggtcg acggcgactg gggagccggg ttcttccaga
   337081 attccgcatg caatttctgc gacgacgtgg ttgccgaaac tgccgatatt tccttcggcg
   337141 acgcctgggt agaaccttat tcctccgatg gactcggaac gaatgtcgtc atcgttcgct
   337201 caccgctcct gcaggcgctc gttgccgatg cggtcaaaga gggaaggctc gagcttcgcg
   337261 aggtcgacag cgacttcatc gtcgagacgc aggcagccgg cttccggcaa cgccgcgagg
   337321 ggcttgcctt ccggcttgcc tggccgcgtt ccggcgtaca gcctagaaag cgcgttgcgc
   337381 cggcgtggaa gggtttgccc gcacagcgga tgcttgtcta cggattgcgc agcgcgatca
   337441 gcgctgccag ccaccgcgtc ttctggttcg ccaggaccat gaaaatacct gccgcctata
   337501 ttcactgggc atcggcgatg ctcgcgctct accagggtgt gacctattca cgcggctgga
   337561 tcggcaagct cgtcgatggc gtctcgatgc gcgggcgcaa gcgttcgaag gacgagggtt
   337621 cgaaggacga gggggcgggc gcatagcgcg cggtcatctc ggcgcagaat tccgcgaatt
   337681 catccggaac gagcggcgca ctcgtatggt ggggtgcaag tccccggtgc tccggcgtaa
   337741 agcagaaagt gacggtcaca tcgaagtctt cgagagcctc catctgccga tcgaaccagt
   337801 cgagcgcgtt cggacggaag cggtcggccc aggagagccc ggtccgcaga taagttactc
   337861 cgaggcgctt catccaggcg accgcgtcgt caaggcgcgg gtcctcgaaa tggaaccact
   337921 gcacgagccc gatatccggc gtgtgccggg caaactcatc gagcgccaat tttggcgagc
   337981 cgtcctcgcg cagcagaccc atgtaaaagt gccggtagta agatgagcct tcggcctccc
   338041 tgtgtcgcgt tgtcgccggc caggcccgcg gcaggtcata gagactgtac cattggatcc
   338101 gctccgcgcg gcccttgagc agttccgcgg ttttcttaag cccccaaagc tgcacttcct
   338161 ccgcgccgaa ggtagagacg ccgacctcgc tgacccagac cggcagctcg gtaacgctgc
   338221 gcagctcctc gagcttctgc ggccattcgt ggatttgcca gaggttccag tcgagcggga
   338281 aaccgtgggc ggcaacggca tcgagatggt cgagcacgcc ctgggacttc atcagggcga
   338341 ggaaattcgg atcgatcggc gaaatcccgc ccagcacccg cgttagcccg ggattgacct
   338401 cccggatcgc atttgccgcc agcttcgcca tatgggcaaa gcggctccag tccggatcga
   338461 tttccggatc ccaatgcgac ttgttgttcg gctcattcca gatcatggcg gcttcgatca
   338521 tcagtacctc cgatttgccg agaagatgcg ccggaaggcc ggctacacgt attcgttcag
   338581 cgtcaggatt tttgcgcccc agtcgcccat cgcgactacc gaaatcgagg ccggcgcaat
   338641 gtcgaagcgc ggccaggcgt cagccgagag gccgaggaca tgacaaacca cggtcttgat
   338701 gacgtccgcg tggctcacga ggacgatctt ctcctgcccg tgccgctgtg ccagggcagc
   338761 gacaagtccc actgccctgc tttgcacgtc gagcatcgtc tccccgccgg gcgcgcgaac
   338821 gaggcttcgc acggcgttcc aacgtcgcca atgcggatcc tcgtcgagaa cgtcgaaggt
   338881 cttgccagac cattctccga aatccacctc gtcgagcgcc tctgtcgtca ggacctccga
   338941 gacgtcggat acggcggcga tcgcctcggc cgtttgctgc gtgcgcttgc gcgggctcgc
   339001 gtaaatcgcc cttatgcctt ggccggaaag gcgcgccgaa agccgctggg cctgctccct
   339061 cccggcggca ccgagcggca cgtcgccggt ccgaccggcg aggtagcagc cgacgttatc
   339121 atgggcggca tgccgcacca gaaggaaagt cgtcgtcact cggccgcccc caggagtgcg
   339181 ccggtctcgc ctgcgatgaa ttcctccagc cgcctgcgcg cctccgcatc ggtaaattgc
   339241 tgcggtggcg acttcatgaa atagctcgaa ggagcaatga gcggcccggc aatgccgcgg
   339301 tcgattgcga gcttggcgca gcgaacagca tcgatcacga cacccgccga gttcggcgaa
   339361 tcccacactt cgagcttcag ctcgacattg aggggaacgt tgccgaatgt cgtgccctcg
   339421 acgcgaatat aggcgaactt gcggtcggcg agccacggaa cgtgatcact cggacccaca
   339481 tgaatgtctc cggccgcgag cggaatgtcc atctggctga ccacagattg ggtcttggat
   339541 attttcttcg attcgagccg ttcccgctcg agcatattga gaaagtcggt attgccgcca
   339601 aagttgagct ggtacgtcct gtcgatacgc accccccgat cgcggaagag attggcaagc
   339661 agccggtgca cgatggtcgc accgacctgg ctctttatat cgtcaccgat gagcggcagc
   339721 ccgcgctcgg caaatttccg ctgccacgat ttgtccgagg caatgaaaac gggaatgcag
   339781 ttgacgaaac cgcagccggc cgcgagcgcc tgctccgcat accagcgcgt ggcgacttcg
   339841 gaaccgacgg gaagatagga gacgagaacg tccgtttcgg tctgccgcag tacgtccgcg
   339901 acatcagcgg caggcacgtc ggattcttcg atctcctcgc gcagatagcg gccgataccg
   339961 tcgagcgttc tgccacgctg aacgaccacg cccgtcgacg gtgcattcgc gaaacgaaac
   340021 gtgttgttgg gagcggcgta gatcgcttcc gcgacatcgc gcccgacctt cgacgcggca
   340081 acgtcgaagg cggcggagat ctcgatatcg ccgacgtggt acccgccgag attggcatgc
   340141 atcagtcccg gaaccggctc gtcctccttc gcgtcgcgat agaatgtcag cccttgaacg
   340201 agcgaggatg cgcaattccc gataccgacc aagccgacgc gaatggattt cgatcccatc
   340261 tttccactac tcctgcgcag tatctacaat gctcgccaaa cccgcgcgcg accgtttggt
   340321 tccttcttct ttctcccgtt tctcgggtga agcggatcga attcagcttc agcgcgttga
   340381 agggcggaca ggaagagagc gaaactccat gctcgtatac ggtgatgcaa agcgcctcga
   340441 gcgcgccgac gaattgtcag cctcgatcgc gtcgcggctg cgcaggatcg aagatcagcc
   340501 cccaggtatc gagcggcaca ccgaactcgt tgcgatcctg ctcaaagccg gagaactggt
   340561 gcaggggctt tcggatgcgg agttcaaaca ggcgagagcc gacgagatct ccgcctcccg
   340621 tgaggctggc gagcgtctcc tcctcgacct tgcgatgctc gtcgcccgtt cctggcaacg
   340681 ggggttcacg gagcgggtta gcgtaccggc ccatgtcgcg aacctgctcg cgaccatcag
   340741 cgcgccgatc tccctcggta tccgggaacc ggaaggctat gccttttacg ctctctaccc
   340801 cgagagctat ctggaggccg cgcgagagtc cggtctgggc tccgatgccg tggtaatcgg
   340861 tctgcggagc atcggaacca ctctttccgc cattgtcgcc gccgccctgc atgcagcgcc
   340921 gccgctgacg ctgcgtccca agggagatcc gtttcgaagg cagcttgcaa tcgccccgca
   340981 gcttgccgga cggctgctgc gcaacccggc agcgggtttc gctattgtcg acgaagggcc
   341041 cggcctttcc ggcagctcgt tcggatgcgt agccgattgg ctcgaggatc atggcgtcgc
   341101 cgccacgcgc attcacttct tcccaagcca caagggcgac cttggaccgc aatcctgcgg
   341161 ccgccatcgc agacgctggg cgacgagccc ccgccatgtc gtggacgtcg acgatctcct
   341221 gatcaagccg gccggctctc cgcgccacct cgccgagtgg gtcggccgcc tcgttggacc
   341281 gcttgagcgg ccgctcgagg atatctccgc gggcggatgg cgaaaggcgc tccccggtga
   341341 ttgcaggcct ccagtcgata tcaggttcga acgaaagaag ttcctcgcgc gcaccgccga
   341401 cggagcgtgg ctcgtcaagt tcgccgggct cgccgacgtc ggacagcgca aactcgtcag
   341461 ggcgcgcctt ctcgccgacg caggcttcgc acccccggtt gccggactgt gccacggctt
   341521 cctggttcag aaatgggtcg cagcgagacc tatggcccct tcggaattgc gccacccggc
   341581 cttcatagcg catctcggtc gctatctggc cttccgggca cgaagcctgc cgccgccaaa
   341641 gacgcaaggg gcgtccatcg cccagctttg cgaaatagct tcggtcaaca ccgaagaggg
   341701 actggggtca gcggccgcgt cacgcctcaa aagccggctc cgaaatgcgg agcgctttca
   341761 tgcggcgatc ctgccggtcg ataccgacaa tcggctccat agctgggaat ggctgggcga
   341821 aggagcacgg cagttcctca aggcggacgc actcgatcac agcggcggcc atgatctcgt
   341881 cggcagtcag gacatcggct gggacatcgc gggggcgcgc atcgaactcg gcctcacgcg
   341941 agacgagcag gccgaactga gagcggccgt atccgaaaac ggctggcgcc ctcccgacgc
   342001 tgagctgcag gagattttcg acctctgcta tgccgctttc cagttcggcc tgtgggcttc
   342061 cgcaaagtcc gctgcagccc cggaggaagt tcaccggctg gagacagccg ctgcgcgtta
   342121 cggcagcctc cttaggaacg cgaccgaggg cttttagggc cgcgacccgc cagtcaagta
   342181 ccggcaaccg cctctgcccg ggcccgggga ggtgccgggc tcacaggcgt ttcgcccaac
   342241 attgcggtca cgctgcatcg ctatcggtcg tatatcctgt ccagcacgtc cgccactgca
   342301 acgaggtagt cgttttcggg gtcgaagcgc tctcctgccg cgaggcgttc cgcccaggcg
   342361 gcggccgctc gtccgcccca gttgtcggga ggaagcgcca gcacctcccg ttgcgtgctg
   342421 cgatagcgtt cggcggaaaa atcgagatag gatccgttga tgttcctcag gctggcaccg
   342481 ccttccgtgc cgtagaaatc ggcgctgatc accgcatcgc accccgcctg cagatgccat
   342541 gagcatgcca ttcgggcgac gacgccgttt gcgagctcaa gcgtggcaat ggcgtagtcc
   342601 tcgacttcgt cgccgtcacg gcgaatggga aggcccttgg caaagagcct gctttgcacc
   342661 cccacgacgt ccgggaaccc gaggacccaa agaagcagat ccacgaggtg aacgccgagg
   342721 tctatgacgc agccgccgcc ggaaagcgcc ttgtcgtaga accagggctt gctcgggccg
   342781 taggcgttgt gaaaggtgag atcgacggcg aagacggtcc cgagttcacc cgatgcgatc
   342841 agatcacgga tttgtcgcat gccctcggtg tagcgatagg aaagatcgac gttcaacagc
   342901 ctgtcgacgt gccgggcggt ttcgaccacg gccgcggtct cgtcgcgcgt tcgtccgagc
   342961 ggcttttggc agaaaaccgc cacgccctgc tccagagcca cgatcgactg agcggcgtgg
   343021 agagcgctcg gcgaggcgat gacgatgccg tcgagcgctt ggtcgagcag cgcctcgagc
   343081 gagttcacga tcgaggcttc cggcgtcagc tcgcgcgccg ccgcagccat ttccggcgac
   343141 ggatcgaaga tcgcgacggt ttcgacggat ccggtttcga cgaccgcttt cattcggtgg
   343201 aagcctattc ttcccacgcc gagaaagccc acgcgggggc gggtggccat cttcggtttc
   343261 gttgaaagct gcattgcgtc actcatggca gatcaccagt gctttgatga aaccttccgg
   343321 ccggtcgcga gtcatgtcga gcgctgcacc gagctcttcg agcgggaacc gatgggtgta
   343381 gagccgcgcg ggagaaatgc gcccggctgc cgtcgcctcg atcgcctctc tcatgccgcg
   343441 catatagact gcaggatcgc gctcatgcgc gttgatcacg tcgagcccgc gccagttcca
   343501 gagctgcatg ttcacctgtc gcgggctgtc ctgatgataa cctgcaatca caagcctgcc
   343561 gcgctccctc gtcagttcgc cggcaagatc gagcggccac tgctttccga ccgcctcgat
   343621 gacgcaatcg cagaagcgcc cgtcggtcag ctgcttcacc tcttcgatga tccgccaatg
   343681 atcgtccatg gggatcacgt cgctcgcacc cgcctgcttg gccgcggcga gtgatgacgg
   343741 cctgcgcgat attgcgatca cccgcgcccc ggcagcgctc acgagctcgg tcagaagaac
   343801 tccgagaaag cctatgccga tgatcgccac ggtttctccc ggcgttatcg cgcttcggcg
   343861 taagatgttg aaggcacatc cgagcggctc gccgggaaag ggctgatccg caagggacgc
   343921 cggcaggcgc gcaatcgcgc tctgatcggc gatgtcatgc gtggcatagg cgttgtagga
   343981 gagtgccgcg acgcggtcgc ccggcgagaa accatgcacg ccctcgccaa cggcgtcgat
   344041 aacaccccag ccttcatgtc cgagcgcccc cggctccgtc ggaaaccgca tccattccgg
   344101 gcctgcccag ggaacgagat tggaggcgca gacgccgcag ccttcaagcc ggatgcggac
   344161 ctggccgcgc ccgggctgcg gcaagggcaa cctctcgatg cgcaccgtgc ccggcccggt
   344221 gacgatggcg gcggacatcg tgtccgtccg ctgagacatc ctgatattca tgtgaattcc
   344281 ctcctcggtg gagacctgtc ctgcagctcg aaaacggtgt cactttgccc ggcggacccg
   344341 cccctgcccg cccaaagcaa agctttgagc aatgttcatg agccttcgcc cttaacttga
   344401 tgttgcagct tttgttcctg atgcgcgcag ttcgcgtgga acactcccgc gaaagagagg
   344461 tttgtacctt ggcatgggtg acgctcggcg ggggatcaaa gaagaacatc aaagaagaag
   344521 aagtcaaaga agaaggaaca tttgcgacgc aggtttgttg gaggtttgtc tctatctctg
   344581 attggtcatc atcaggtgca atatgacaaa agtacttgtt accggcggct gcggtttcat
   344641 tggccggcat gtggtcgaag agcttctctc tgggaactac gagttgcgca tcctcgatgc
   344701 gctgaacgaa caggtccatg cggacgccca gatcaccctg ccaccggaag tagatatgcg
   344761 gcgcgccgat atatgcgacg ctgacgcggt gaagagcgca ctgaaggacg tcgatcacgt
   344821 cattcatctc gctgcggagg tcggcgtcgg ccaatccatg tacgagatct cccgctatgt
   344881 gggcgtgaac gacctgggca ccgccgtcct gctcgaggcg atgatcggca tgccgatccg
   344941 gcggatcgtc gtcgcctctt ccatgagcgt ttacggcgag ggcttgtacg agactgcggc
   345001 cggggaacgc cgcgcgcata tccggcggtc tcccgccgag atcaagacgg gtgcgtggaa
   345061 cccgtccggc cccgatggcg agagcctgaa gccgatcgcg acggacgaga acaagccggt
   345121 cgatcttgcc tccatctacg cactcacgaa atatgcgcag gagcgtcagg tccttatatt
   345181 cggtgaagcc tatggcatgg acgcggtggc gcttcggctt ttcaacgtct acggcgccgg
   345241 tcaggcactc tccaatccct ataccggagt gcttgccaac ttcgcctctc gacttgccaa
   345301 cgggcaggcg ccgatggtct ttgaggacgg ccgtcagaag cgcgacttcg tccatgttcg
   345361 cgacgtcgcg cgcgctttcc ggcttgcgct cgaacagccg cacgccgcgg gccacgtcat
   345421 caatatcggc agcgggcacg cttacgcgat cgctgacatc gcctcgctgc ttgccgatgc
   345481 gatgggcgtg ccggagatcg ggccggagat catgcacaag gctcgttcag gagatatccg
   345541 caattgcttc gcggatattt ccaaggcgcg cgacctcctc ggcttcgagc cggcgcaccg
   345601 gcttgaagat tcgctcgcgg atttcgccca atgggtccgc agtgccggcg cgatcgaccg
   345661 cggcgccgag atgaagcgcc acttggaagc acgggggctg gttctatgag cggccggacc
   345721 gtcgaaaaaa gtcggcatct ggcgacgcct gcgctctccg gaaaggcggg gccgatcctt
   345781 gtcgttggag gcagcggctt cgtcgggagc aatctcgccg acagctttct ccgtgacggc
   345841 gagcacgtga tcgttctcga caatctcagc cgcccgggcg tcgagagaaa cctcgaatgg
   345901 ctggtggaga gccacgggcg cgccgtcgag gccgtcaccg ccgacatccg cgatctcgcc
   345961 gcaatccaac ctgccttcag gaatgccaag gccgtattcc attttgcggc tcagacggcg
   346021 gtgaccacaa gtctccagca gccgaccgag gatttcgaga cgaatgcgcg tggcacgctc
   346081 aacgtgctcg aagccgcacg tctggctggg cgcagctcgc ccgtgatctt cgccagcacc
   346141 aacaaggtct atggcgcgct cgagcacatg gaaatgagag acgtgcaggg ccgctacatg
   346201 ccggtcgacg aggcgacgcg cgcgcatggc gtcggcgagg cgcaaccgct cgatttctgc
   346261 acgccctatg gctgttcgaa gggcgttgcc gatcagtatg tgctggacta tgcccgctcc
   346321 tttggcttgc cgaccgccgt tctcagaatg agttgcgtct atggcccgag gcagttcggc
   346381 acagaggatc agggctgggt agcgcacttc ctcatacggg cgctcgccgg cgagccgatc
   346441 tcgatctatg gcgacggcaa gcaggtccgc gacatcctcc atgtcaccga tgcggtcgcc
   346501 gcttatagag cggttcttaa agcgatcgac ggtctgaagg gtcgcgcttt caatttggga
   346561 ggcggacccg acaatgccgt cagcattgtc gaggtgctga acgagatcga gatcttgacg
   346621 ggccgtcggc tctctaccgg gaaaagcgac tggcgcgccg gcgaccagct gtattttgtg
   346681 gccgatacgc gcgcgatcgc cgatgcggtc ggctggaggg cgggaatggc ttggcgcgag
   346741 gggctgcgca atctttacgc ctggcttgtc gaagatcggg tcggcgtcgg aaatatccgg
   346801 cgtcaacagc ggagggtccc tgcatgagcg tccatgccct ttccggctca agacaagagg
   346861 tccgccacga cgccccgagc ccgttgccgc ggcggatatt gatgaccgtc gatgcggtgg
   346921 gcggtgtctg gcgctatgcg gtggatctcg ccgaagccat gcgccgttcc ggcgtcgaga
   346981 cgctgatcgt cggcttcggc ccggcccctt cccccgagca acggcgcgag gcggagagca
   347041 tcggccggct cgaatggtcg gatcagccgc tcgactggat ggtggaagat gaaagtgaac
   347101 tctgcggcgt tccggacctc ttgtccgaac tggcgctcaa gcactccgtc gatctcatgc
   347161 acctcaacct gccttcccag gcttcgggaa taacggctga gattcccgtc gtcaccgttt
   347221 cgcattcctg cgtagccacc tggttcgagg cggtgcgcgg atccggcttg ccaaccggct
   347281 ggtgctggca gaagcgattg aaccgaattg gattcgaccg cgccgacctg gtgcttgccc
   347341 cgagccggag tcatgccatg gcggtgacgc gttgttacgg tccggttcgc gatctcgcgg
   347401 tcgtctacaa tgcgagccgg aacgcatcct ccatctccgc caaggagaac tttgcttttg
   347461 cggccgggcg ctggtgggac gaaggcaaga atggagccgt actggacagg gcggccgccg
   347521 atataggctg gccggtcgtc atggccggtg cctgtgacgg ccccaacggg caacgcctgg
   347581 cgattgcgca tgccgatcac aagggcgaac tcagtcacga cagggcgatt tcgctgatgt
   347641 cgagggcggc gatcgtcgtt tccccttcgg tctacgaacc attcggtctg gtggcgctgg
   347701 aggcagcacg cgccggtgcg gcattggttc tcgccgacat cgaaacctat cgcgagctct
   347761 gggagggcag cgctcttttc gccgatgccg aggatcccgc cgccttcgcc ggggccgtca
   347821 accggcttgc ggaggatgcg gggttcaggg ccgagctcgg ccggcgagcg cagtcgcgcg
   347881 gttccgactt cacccttgag gcccagcgcg aggcgatatt cgccgcctat aggcgcgtga
   347941 tgcgcgggga aaatcgacgg acggcagcgg agtgagcgga tgcgatttct tttctacacc
   348001 cactcattga tttccgattg gaaccacggc aatgcgcatt ttctgcgcgg tgtcatgcgt
   348061 gaaatcacac gccgcggcca tctggccgtg gcgcttgagc cgggcgattc ctggagccgc
   348121 cgcaatctga ttgccgatca gggcatcgga ccgatcgccg cctttcgcaa acactttccc
   348181 gatttgcagg tcgcgatcta cgagtccgat ttcgaccatg aagcggcagt cgccgaggct
   348241 gacatcgtca ttgtccatga gtggaccgat cccgctctga tcgccgaact cggccgcatc
   348301 cgcctgaagg gtggacgctt cacgctggcg ttccacgaca cacatcaccg cgccgtcagc
   348361 gccaaacggg acatcgccag gctggacctt tccggttacg acttcgttct ggctttcggt
   348421 gaggcgctgc gcgagcgcta tctgcaggcg ggatggggaa ggcacgtcca tacctggcat
   348481 gaggctgccg acacttcgct gttccatccg atgccggagg tggaaaagcg tggcgagctc
   348541 atctggatcg gcaattgggg cgatgacgaa cgcagcagcg aaatcatgtc cttcctcgtc
   348601 gaaccggcaa aaaagctgaa actgagggcg acggtccgag gcgtaagata tcccgacacg
   348661 gcgctcaggg ccttgcgcgc cgccgaaatc gactatggcg gctggctcgc gaacgcagcc
   348721 gtcccgcggg ccttcgcgga gcaccgggtc accatgcaca ttccgcgccg accctacgtg
   348781 gaggcactcc cgggcatacc cacgatccgc gttttcgagg ctctttcctg cgggattccg
   348841 ctggtctcgg caccatggac ggatgccgaa gggctattcc ggcccggcaa ggatttctgc
   348901 atcgccaggg acggcaaaga gatggcgcga cttctgcgtc aacttctcgc ggaaccagcc
   348961 ttcgcaacgg agatggccgc ttccggactg gagaccgtcc gagcacgcca cacatgcggc
   349021 catcgcgtcg acgagcttct ctccattctg gccgcctaca tgccgcacag caacgtggaa
   349081 cgcacagtca ccgaggaggt ccagctatga aactggcatt ttacggatcg agcctcgttt
   349141 cggcctactg gaacggcgcg gccacctact atcgcggcct gctccgtgct ctcgcgcaac
   349201 ggggctatca gatcaccttc tatgagcctg atgtctacga ccggcaaatg caccgcgaca
   349261 tcgatccgcc cttctggtgc aaggtcgtcg tctacgaagg gaccattgaa ggtctgaaaa
   349321 gcgtcgccgg gaaagccggt gaggccgaca tcgtcgtcaa ggcgagcgga gtgggctttg
   349381 aggacgagtt actgctcgcc gaggtcatgg cggcggcgga tccagcggca ttgaagatct
   349441 tctgggacgt cgatgcacct gccacgctgg ccgatctcag ggccgcgccc gaccacccgc
   349501 ttcgtcgcgc gcttccctct ctggatctcg ttctgaccta tggcggcggc gatcccgtgg
   349561 tcggcgccta tcgggctctc ggtgcccgcg aatgcgttcc gatctacaat gccgtcgatc
   349621 ccgagacgca ctatccggtt tcgccggacc cgcgctttaa cgcggatctc gccttcctcg
   349681 gcaatcgcct gccggaccgg gaggagcggg tggaagcctt cttcctcgag ccggcgcaaa
   349741 agctctggca gcggcgtttc ctgcttggcg gagcgggttg gcatgacaaa tccctgtccc
   349801 cgaacgtcgc ctatatcggt catgtcccga cggcggacca caatgccttc aacacgacac
   349861 cgactgccgt attgaacatt tcgcgctcca gcatggccga taacggcttt tcgccggcaa
   349921 cccgcgtatt cgaggcggcc ggcgccggtg cctgcctgat caccgactac tgggagggga
   349981 tcgaactttt cctgaagccc ggagaagaag tgctggtcgc cagagacggc cgcgacgtcg
   350041 ccgagctgat gcagaaactg accagcgcta acgccaggga gatcggcgag cgcgcgctgc
   350101 gccgcgtgct ggccgagcac acctatgcgc atcgtgccgc agaagtggac cgcatcttgc
   350161 gccaggcgcg ccggatggag gctgccgaat gaagcgccca ctcgacatcg tcatcctcgg
   350221 tctctcgctg tcctcgtcgt ggggcaacgg ccacgcgacg acataccggg ctttgcttcg
   350281 tgccgttaac gccgccggcc acaaggtgac gtttctcgaa cgggacgtgc cgtggtatgc
   350341 ggacaatcgc gatctcgccg tgccggactt ctgcgatctg gtgctctatg acgacacgga
   350401 cgaactcaca cagcggcatg cgcgaaagct cgccgatgcg gatgccgtcg tcgtcggctc
   350461 ctacgtgccg gatggcgtgg acgtcatcga cgctgtcgcg gatctggtac cgaagcgcct
   350521 gtgcttctac gacatcgaca cgcccgtgac gctcgccaag ctcgaacgcg gcgacgagga
   350581 atatctcgcc cgaaggcagg tggcgttctt cgacatctac ttttccttct caggcggcaa
   350641 gacgctcgac aggctgcgtg acgagttcgc ggcacggcgg ccggtgcctc tttattgtgc
   350701 cgtcgacctc gaagcctacc gcaacacagg cgcaccgacg aagtgggatc tcggctacct
   350761 cggcaccttc agccccgaca ggcagccggt gctcgaacgc ctgttgatcg agccggcgcg
   350821 ccgcctgccg cacatgcgct tcgccgtcgc cgggccgagc tacccttccg acatccactg
   350881 gccgccgaac gtggagcgca tagagcatct gccgcccggc gaacatgctg aattctacag
   350941 ccgccagcgc tttacgctga acgtgacgcg cgccgacatg gtcgcggccg gctggtcgcc
   351001 gagcgtccgc ctcttcgagg ccgcagcatg ccgcacgccg atcgtcagcg actggtggga
   351061 gggcatcgag aatttcttcc cgcctggcga agccgtggtc attgcacaga gcagcagcga
   351121 tgtcgtcacg gcattgacga gccccgatga agcccaacgc gaagcacttg ccgattgcgc
   351181 ttatcgacgc gtcgccgccg agcacagttc cgccgcgcgc gcacgcagct tcgtcgaggc
   351241 actcgaaagc gtcgccgcca gaacggatct cgcaacccag cgtgtcgagc ggcggcttcc
   351301 ggtttaaccc aaaaggagaa cggccgatgg ctaaaagaaa caaagcaagc cgaggaaaga
   351361 tcatcctggt tgccggcggc gccggctttg tcggatcgca cctttgttcc gcacttctcg
   351421 gcgccggcaa ccgggtgatc tgcctcgaca gctatctaac cggctcccct gccaacctca
   351481 ccggtctgca gaacgacccc tatttcgcga tggttgaaca ggacgtctgc gacgaaatcg
   351541 acatcgatga accggtcgat cagatctata atcttgcctg ccccgcatcg ccgcccgcct
   351601 atcaggccga tcccatccac acgatgatga ccagcgtgac cgggacaggg aacctcctgc
   351661 ggcttgcgga aaggcacgga gccacgcttc tccaggcctc cacaagcgag atctacggcg
   351721 atcccgagga gcacccgcag caggagaatt attggggcca cgtcaactgc acgggtccgc
   351781 gggcctgcta cgacgagggc aagcgcgcgg cagaggctct gtgcttcgac agtctgagag
   351841 ggggaagcgt cgatgcgcgg gtcgcccgca tcttcaacac ctacggcccg catatgcgcc
   351901 ccaatgacgg ccggatcgtt tcgaacttca tcgtccaggc gctgaagaac gagccgctca
   351961 cggtctatgg cagcggtgag cagacgcgct ccttttgcta cgtatccgat ctcgtggacg
   352021 ggctgatccg gctgatgaac cgtgaggaga accctgcggt gccggtaaac ctcggcaatc
   352081 cgggcgaatt caccgtcatc gaactggcgg agctggtcct ctccagaatc gagacaacct
   352141 cgacgatcgt ccatgagccg ctgccggcgg acgatccgca gcgtcgccgg ccggatatcg
   352201 cgcgcgccag gaagcttctc ggctgggagc ccaaagtccc cctggaggaa gggctgacgc
   352261 atacgatcgc ctggttccag agcgcccttg gcagcagccg ccccgaacgc aggaccggcc
   352321 gcacccgtcg ccagccgcaa cttgccgccg tcacgcagga tctgtgatca tggttcagca
   352381 gatgagagac cggacgaaca tcgcgcacga aatcgcggcg ctcggtccgt ggttccacaa
   352441 tatgcggatc gggggcatcg agacggcgcc cgatcatttc ctcggcgact atcccgcggt
   352501 aaagtggaaa gccttcagac atgtcgtgcc ggaggacctc gaaggaagga gcgtcctcga
   352561 tatcggctgc aatgcggggt tctacgcgca ggagatgaaa cgccgcaatg cagggcgtgt
   352621 gctcggcatc gactcggatc cccattatct gcggcaggcg aaattcgccg cagagcaggc
   352681 cggggtcgaa atcgaattca ggctgatgtc ggtctatgat gccgcgcggc tgcgggagaa
   352741 gttcgatctc gtcattttca tgggcgtcct gtaccacctt cgccacccgc tgctggcgct
   352801 cgaccttctc tacgagcacg tcgtcggaga ccagatgctt ttccagtgca tgcagcgtgg
   352861 ctcggacgcc gtggcaagcc tcgaaggcga ttatgagttc ggcgaatggg ggattttcga
   352921 ccggcccgac tatccgaagc tgttcttcgt cgaacatcgt ttcgccgatg atcccaccaa
   352981 ctggttcatt ccgaaccggg ccggcgtcga ggcaatgctt cgaagcgcgg gcttcgtcat
   353041 cgaagccaat cccgagcggg aggtctatct cctgcggcgc ggaaagcgtc cctatctgga
   353101 cgagcccact ctcagtgttc tcggggggcc ggcaggtctc taaatcggag cactttgcca
   353161 tacgggcctg ggagatcagg gctgaagacc gaaaaactcc cggattgcac ccacttggta
   353221 gtcgagcatg tgtcgaccct cctgaatggg atggcccagt ttctccgcct ccatcagcag
   353281 acgggttctc gcaggtttca taatcgcctc gcacaccagt gcacctcgcg aaaggctggc
   353341 cagatcgaag ggaagaccgt cggagggcga catgcccgct gaggtggcat tgatcgcgag
   353401 atcatcgccg atggatggcg ggctcacaat gatggggata gcggcatagg ccgccgccag
   353461 acgctcccgc aagcgctcag cgcgcgcttt atcgacatcc cagacctgtc atccttcgtc
   353521 ggcggcaggc tgctggacga cgatgctaat gttctgatgc gtttcggcgg cggcgttaag
   353581 ggcatgcttt gggtgtcgca agtcgcaccc gggaacgaga atgctcttct aatacgcatt
   353641 ttcggcagcg agggcggcgt cgaatgggcg caagaggaaa ccaatcactt gcgcttctcg
   353701 cgctcggcga gcctgagcga atcattacgc gggcaagcgg ggccgtcgga cgcgacgggc
   353761 attacgcgac acgggttccg cccggccatc ctgagggttg gatcgaaggc ttcgcgcaaa
   353821 tttacagcga tgcggctgag gtgattgcag ctcacaatga acgccgcgcg ccagaccccg
   353881 gggcgtgcct cttgccgact gttcacgatg gcattgatgg aatgcgcttt atcctcgcgt
   353941 ccgtgcaatc ccatcaaacc ggacgatggc tgcggacgga agggcgcgcg ctcaccacct
   354001 gcccgccggc cttatccgaa gcggcgaagc tgggccgctt ccttctcgag caggtcggcc
   354061 acctcctgaa gcgtcatatg cgtaacgcag agatgaatcg cgcattcgag aaagcgcgtc
   354121 gatgagcgcc gtaaatacaa ggcttcctcc ctggcggcca attccgataa aggatctttc
   354181 ggtgggcgtc gacgttcggg catctggagg ctccttcgat tcgctagttc gagaactcgg
   354241 tcggctgctg aacacgcatt cacggcgaga acaggccgcc ggcgtagata agggcgccca
   354301 acaggatggc cccacctatg atcgccaggc tcattccgag cctttgcttg ttcgcctcgg
   354361 cggtctccgc cgctgaaagc ggtcgcatcg catcattgta ctcggttgcg gtgtcggccg
   354421 gcctcccttc cgcttgcccc acccgggccg ttcggatcgc gtcctcgccg ggaggagttc
   354481 ccgcagcctc ggcgtcggtt tccagtggcg ccgcagcggg gtcgaatccg cgccttttgt
   354541 ctcccgttct cccatgctgg atatcgccac gcacctgtgc gggattgctt gccggattcg
   354601 ccatgatcgc tcctttccgc tccgcgactc aaccggcgtt cgcggtattt gttccaagct
   354661 cctccgcagt gtcaggatgc ggccaatctc cgccaggcgt gcgctggaga ccccccgaga
   354721 tccctcgggt ggcgggggtc cttctctcca tacctgtgct tgtcacaagt cgccgcgacg
   354781 gcccgcggcg catcgtgatt ccgcaaggcg ggcggtcaat tactcttgaa ctggccgctg
   354841 cagccggtcc ttggcggcgt catgggcttc caggaccgct tcgccggcct tgtccagaat
   354901 ttcctgcccg gcttccatcg cttgcgcgac gccggcattc gctcttgccg agatgtttga
   354961 ccgcatatct tccgccatgc cgcccatggc cgcgtcttcg gcttcgctat ggggcaatgc
   355021 ggcgcctatg gccgcgccag cagcgaaggc aagcgcacct ccgacgagcg gctggtcgcg
   355081 gaagtgcctg agtatggccg cgttcagctg cgcaccctgt tcttccagcg accgcccggc
   355141 accttgcatg ctatcggcga aagatctgcc ggctcctgtt acggaggcgg acatccgacc
   355201 cgccgcagcg ctcacctgtc tccatgtcct ggacgcccag ccggatgcct catcgaacaa
   355261 ggcgcccgtc tcgtcccgta tatcttcgat ctgcttgccc gccgcgtcgg caaagccgcg
   355321 atagaccttt ccggcgggat cgatgaaatg gccggcgcgc cggcccgcat cgtcggtcaa
   355381 ggcacgaaat cggctgccgc tctcatccgt gaagtggctg tacctttcgc cgaagctcga
   355441 ctccaccgga cccacgcgcc tcacggagcc tctcaccggt gcaagcggat aatcgtcgtc
   355501 ctgctcttcg tgtcgtggcg cacgggatgc cgggttggcg atcagccaag ccaggctgac
   355561 gcccatcaag gcaaccggga tcgggttcga cttgagcgcc accccgagat tgctgagata
   355621 ttcggacccg ccgctcgttt tggcatattc gagcagctca tccatcaact ctcccggcga
   355681 catgcgctcc tgaatttcat ggagtttttc ttcaattcgc tggcgatcgg cctcaatctc
   355741 gcgctgcagt tcggcagcgg agtgcgtatg tgcggaatcg ttcattgcag tctctccttc
   355801 accacgttgg cgtcgcgctg cagggaggcg gccgtcctgt cgaatttgat gctgcctccc
   355861 ttgagtgccg agaggccgcg tgaaatcata atccaggcaa gcaaggcgac aaccacgccg
   355921 acgatcgccg ccgacaaggc atcggcattc gcttcgctca tgccttgggc cacgagaaac
   355981 gcgcccaagc cttgaacaac ggcactaagc aggacgccga ccgcgccgat ggcaaagatc
   356041 aagcccacga gcaatgtctc gaagctgccg acggcacgat tcaaattctc ggacgcctcg
   356101 gcctttgcga ggtcgatttc cttccggaaa agtccggata tgtccgccac caggccggtc
   356161 atcagctccg acagggggcg ctcgtcccga tgattagcca ttatagggtt ccttttcgct
   356221 ggtttgacgg tttcctcccg aagcatcctg tccgttccgg cgcggaggtg acgcggtgag
   356281 gaaccgactt gcggccagtc ctgcgattgc agccatgccg aggaaggcaa gcggctgctt
   356341 gcggccgaaa tcttcgacca tcccggcgat ctcgccgagg ttgcggccct cagccttgcg
   356401 cgcgaagctg tggagcgacg tgccgatctg cttggcatag cggccgatgg cccgctgatc
   356461 cgactgttcg agttcgcttc cgaccttctc gagggctgcc gcaacgcctt ccaactggcg
   356521 tgcagcgacg tttttttcgt cctcaacagc gcggctgatg gctgcctttg cctgctcagt
   356581 ctgttcgccc gcgaactgct taaactcgtt gacatcttcg cggacggcat tttgaagatt
   356641 gcggtctgcc gaatcccggc cgatatcgcc ggtctgcacg ccgcttacgc gctcgatgcc
   356701 ctgcgcggcc gtcagaggcc tgcccagtgg atcgcccgac ccgcggcctg ttgtgtcatt
   356761 ggtcatgttg ggttcctccc aagattaacg ggaatcgtta ttgtgtacgc aatcaaacga
   356821 gctatttaga accttgttcc ctgcaatgac gcaggcgggc cgttgccgag ccgacagccg
   356881 tcggattagc gggtccggtt ctccggggac tgctcgtaaa gttcttcgac ctttcgcttt
   356941 tgcgcttgtc tttcagcccg cgagagcggc ctctgcctca aaatggcata ggcgacggca
   357001 gcaccgagga tgaaggcacc gccgcctgtg acaaaaagcc agaaatagtt cgtcagcatc
   357061 gtcgtatctc cttgccagag ccaaccggct cggccgccga aggttccaga cgagcccgtt
   357121 tctcaccttt ccttcgtctt gggcgaagct tgcattgcac cggaaccgag cgtctgctcg
   357181 ccggtttgac cgatgtcagc caccgagcaa aggagaacct catggccgga aaaaagagct
   357241 ggagccgcga cgtctatgaa cactatccgg aatcggatcg gcgctggcgt gcccgctcgt
   357301 acgaggacga gaggcgtcgc gatcctgccg agggttcgcg gctcgtgggg gacgagaact
   357361 cagagtattt cccaggtgcc gaacccggtc gcgccggcgc gtttcgcggc acaggaaaaa
   357421 cccatagccg ttggaacgga gaacgcgact atggcccgga taccttcggc ggcgggggct
   357481 accacggcga cgacgattac ggccaccgat atcgccatgg cggcaggggc atcgaggggc
   357541 gcggctttct cgaacgcgcc agtgacgaag tctcgtcctg gtttggcgac gaggacgccg
   357601 aacgcagacg catgcaggac cagcatcgtg gcaagggccc caaaggctac acccgttccg
   357661 acacccgcat tcaggaagat gtcagtgatc ggttgagcga cgaggggatg ctcgatgctt
   357721 ccggcatagc cgtctcggtc gcaaatggag aagttcaatt gagcgggttg gtcgattcga
   357781 agtgggccaa acgccgcgcc gagaactgcg ccgacgccgt ctccggcgtg aaacatgttc
   357841 agaacaatct ccgcgtccga ccgtcgggag gcgcccccgg ctggaatgcc gggaacaccg
   357901 accgcaacat tgcttgaacg cacaagatcg tgggccgtcg ccttggtcac atccctgcaa
   357961 gcttcccggt tacggagatg taatcgactg aacctggagc aaatgcgttc tgacggtcgg
   358021 atatgcggat tcggcaaacg ttttcagggc cccggcctcg cctcgctcag cataggtctt
   358081 gagaagttcc agcgcatcct catgcgcagt aacctgcgac gacagataag ccggatcgaa
   358141 ggtcgcgccg tttagcgcct gcaaggcagc aagcctctcc tgcccggcct tgtcgagcga
   358201 ctgggaaagc tccacgccgt ccttccgtgc tgcttcggcc agttccttgc cggcacgcgc
   358261 atgatcagcg agcatccgct cggcgaactc cagcacctgg cgtccctcgc cccgctgccg
   358321 cgccagttcc gccgatttca gctcgaaaag gttcgacatc gacattttcc gcgcgaactc
   358381 ctgaggctcc gttggctttg tctgagcgct gaccgcctga atcgagacga agcacagcat
   358441 aattgctgca agggtgatgt tgactgttct cattggggca cctccggaac cgctctaacc
   358501 tccgggctcg ctcatcgttc cgcagttccg gtggagcacg gacggccgca ggccggtcta
   358561 aggaactttc ttggggccgg tctggttgta tcaaccgaga ggccgcgcaa cggcctatgg
   358621 gagcggtcac cccgcgtgac cgactaagct tatgcaaacg gcactgttca tcgcgatccc
   358681 ggccctgccg ctcggaacgg cgctcctgct tctctggttc ggtccgctct ggcgccagca
   358741 agcggcccca tggaaccgct cgtcgatctg gtgccacgga tcacccgttc tggaccggca
   358801 aggcccttgg cgaacactcg atcctacctg agcacgcgtc gggacgaaaa gggcgagcgc
   358861 ttcatggtgc attcggcttg atggacgccc cttgaccagc tcgcgccaac gctgccctga
   358921 cacaggccgt tacaaaaatc ccatccagcg cacacatcgc caatacatgc cggcggttca
   358981 atggtcgcac tggcaacgag gacgagcctc agccgatcgt ggaaagggat acctcaatga
   359041 aaacgtctcg gatcttggca gccgcgctgc tggccgttgg aagcggatta gcgctgcatg
   359101 cggccaatgc gcaacaggcg ggattgcatc gcaccgatct cctgcagcag gatatcggcc
   359161 tgcccgggcg agaggcaatt caggtgcgcg tcgacttcga cggcggtgcg gtttccatca
   359221 agcactccca tccgggcgaa gaggtggcct atgtgctgga aggctcgctg gaatatcagc
   359281 tcgaggggag agccccggtc acgctaaacg ccggcgaggc cctgttcatt ccggccggtg
   359341 tggctcatgt cgccagaaat gtcggtagcg gtaaggcgtc ggaactggcg acctatatcg
   359401 tggaaaaggg atctccgctc gtggttccag ctgagtgagc gtcagagatt taccccttgg
   359461 ctttagtttc gacatcgcgc tctgttgaat tgcgaacatg gtccggcggc ggtgccgcat
   359521 ggtagcgccg ggcctgttga ccgccgactt gcggaccgcg ttccggttct tgctcgtgca
   359581 cgatccggcg agtacagcta ccaaggcatt ttcgtttcga tttaaaatgg cagtcacagg
   359641 ggttggagat cgcgcgtgga gcatatcgat cacatcttga tcgttgatga cgatcgggag
   359701 atccgggaac ttgtatcggc ttacctgaag aagaacggcc tgcgggcgac cgccgtggcc
   359761 gacgggcgtc agatgcggac gttcctcgag gcaaatacgg tcgatctgat cgtgctcgac
   359821 atcatgatgc cgggcgatga cggcctcgtg ttgagccgcg aactgcgtgt cggccggcac
   359881 aaggcgacgc cgatcgtcat gctgaccgcc cgctccgacg agatggatcg catcatcggg
   359941 ctggaaatgg gcgccgacga ctatctcgtc aaaccattct cggcgcgcga actgctggcc
   360001 cgcataaagg cagtcctgcg gcgcgcgcgc atgctgcctg caaatctgca ggtctcggag
   360061 gcaggtcagc tgttgcgttt cggccaatgg aggcttgata cgacggcgcg gcatcttgtc
   360121 gacgaagacg gtaccgcaat agcgctcagc ggcgcggaat accggctgct gcgcgtcttc
   360181 gtcgatcacc cgcagcgcgt cctcaaccgc gatcagctcc tcaacctcac gcaggggcgc
   360241 gaggccgaac tcttcgaccg ctccatcgat ctcctggtga gccgggtgcg tcagcggctc
   360301 ggcgacgatg cccgcgagcc gacctatatc aagacggtcc ggagcgaggg ttacgttctt
   360361 tctatgccgg tcgagatcgt ggaacctcgc tgatggtgcg ccgaacgggc cttggagtta
   360421 acctgtggcc gcacacgctc agggcgcggc ttttcgtcat cctcctcgcc gggctgacga
   360481 ttgcacatgc gatgtcgttt gctgtgctgt tttcggaacg ctacattgcc gccagatcgg
   360541 tgatgttcaa cacgcttgag accgacattg cgacgtcgat cgccatcctc gaccggctcc
   360601 ccgcggccga acgcgccagc tggctggacc ggctcgctcg cggatcatac cggttcgttc
   360661 tggggccggg cattcccggt gatccggtgc tcacccgggc cgacgccgaa gtcgccgaca
   360721 aggttcgggc tgcgataggc gcgcaatacc ccattgagct tgaatcggtt cccggcggca
   360781 ttcgccgcct tcaggcgcat cttcgcctga gcgacggcga gcccctgacg atcgacgtga
   360841 cgccaagagg ggtcatgccg gttgccgact ggttgccttt cgttctcgtc gctcagcttt
   360901 ccctcctggt cctgtgcagc tggcttgctg tgcgccaggc gacccgtcct cttgccgacc
   360961 tcgctagggc cgccgacacg ctcgacccga acagcaagac gccgcgtctc agcgagaccg
   361021 gcccgaggga agtcgcctat gcggcgacgg cgttcaatgc gatgcgggat cggatagcgc
   361081 agtatctgga ggagcgggtc cagatactgg ccgcgatttc gcacgatctg cagacaccga
   361141 tcacgcgcat gaaactgcgc gcggaaatgg cggacgattc catcgaaagg gacaagctga
   361201 tcagggatct cgaagaggtt gaacgtctcg tgaaggaagg tgtcgcctat gcgcgcagcg
   361261 cccacggcaa ggacgaaaaa gcatcgcgca tcgatctcgc ctccttcgtc cagagtcttg
   361321 cctatgatta tcaggataca ggcaaagcgg tcaccgtggg ggaattggga gatggcacaa
   361381 tcgtgacgag gccgcacgcc ttgagacgca ttctcaccaa cctggtcgac aatgcgctga
   361441 agttcggcgg cagtgccgag attgaacttc agcgccgcgc cgacggcact gtgctcataa
   361501 aggtgtcaga tcgaggtccc ggcattccgg aagaccagct ggatgcggta ttgcagccct
   361561 tctttcgctt ggagcaatca cgcaaccgcg atacgggcgg gaccgggctc ggtcttgcca
   361621 ttgcccaaca gctggcgatc gtcatcggtg cttccttgac cttgcgcaat cgcgacggcg
   361681 gcggccttgc ggcggagctc gccatcggag ctgcctgagg aatggtcgac ggcgccatac
   361741 agagaagcgg ggcggcgcct gccgccccgc tttgttgcgt cgatccgggc tgcatggctc
   361801 aggatggccg gggctccccg gattgctccc ggacaatgta atctgcgtac cagacgggcc
   361861 agtcctcgtc cctgtgtccg agttgctttt catactcgcc gtgagccgcc tccgcacggc
   361921 ggaatgcgct tgccagatca gcggcggagc tgaacgtcgt ggcactggcg tcgacgcggc
   361981 ctggtagtcg cgtggtgacc tcctgaagca gccagccgtt accgtcagga tcgcggaagg
   362041 aagcgtagga acgatagctg cggcgttctg ggtcagggcc gccaaccctg agccgtccga
   362101 acaggtaagg ctcgtccttg ccggcatgca catcgccggc gtggaacact tcgctgatat
   362161 cgacaccgcg accccgcaac gcctcgcggg cggcctcgat gtcggaaacg atcaggtaca
   362221 gtccctgtgc ggaacccggt tccgcatcgg tcacatgctt cccgaagatg accgaggctc
   362281 cggatccagg cggagtgaac tggatcacgc ggtagtcatc gggtccggcg aagtcggcgt
   362341 cgagccgcca gccgaggctc gtatagaatt cctttgcgcg gtcgatatcc gacacgggca
   362401 cgacgacaat ttcgagcttc atatcgacgg gcgcgtttct ggtgctgtca gcggtcattt
   362461 ttctctcctt gtatcaggag gcgcagggcg ccttttgtct ctcgattgac gatgaaggac
   362521 gggcacgttt cccgtttcgt ccgactgtcg agagacatat gccgtcccgc acatgtatgg
   362581 gatatttcgc aacagggcga aattgtaagc caatgctcac agaccacggg acgaatacgg
   362641 tctgatacaa aggcattgct ccgcgggcgg tcagagtcga tcggcgtcca cgaccgcctg
   362701 ggcgaaagcc tgtggcgctt cctgtggcag gttgtgaccg atgccgccgg tgatcaaacg
   362761 atgctcgtac ttgccggaga actttttggc ataggccgcc ggatccggat gcggcgctcc
   362821 attggcatcg ccctcgagcg tgatcgtcgg cacggttatc accggcaagc tggcgagccg
   362881 atcctccagc tcgtcaaatt cgcgctcgcc atcggcaaga ctgatccgcc agcggtaatt
   362941 gtggatcgtg atatcgacat ggtccgggtt ctcaagggcc gccgcgctgc gcgcgaaggt
   363001 cgcgtcgtcg aactcccact ttggggaagc aagctgccag atgagccgcg cgaagtcatt
   363061 ccggtgctgt tcgtacccgg cccggccgcg ttccgtggcg aagtagaact gataccacca
   363121 ggcgagctct gctttgggcg gcagcggcat cctgttggcc tcgcggctgc cgatcagata
   363181 accgctcacg gaaaccatcg ccttgcagcg ctccggccag agtgcggcga tgatgttcgc
   363241 ggttcgcgca ccccaatcgc agccggcgac gacggccttg tcgagaccaa gcgcgtccat
   363301 gagggccacg atatccgcgg ctatcgccgc ctgctggccg ttgcggggcg tgtctgccga
   363361 aagaaagcgc gtcgtgccgt agccgcgcag atagggaaca atgacccgat agcccgcctt
   363421 tgcaagcaga ggcgccacat cgacataggt gtgaatgtca tagggccatc cgtggagcag
   363481 gatgacgacg ggtgcgtcgc gcctgcccgc ctcggcatat ccaatgttga ggacacccgc
   363541 attgacctgt ttgatctccg cgaaggatgt attcgtcccc ggcgctgtcg ccggaatgga
   363601 cgtccccctc gccgattctg cgagggcagc gcgccccatg ccgaactgtg ctgcagcgac
   363661 tgccaatgcc gccactcgca tgaaccgccg ccgcggcaga ttgaattcgc ctgtcatcga
   363721 tcttctccgg attgtgtgaa ccacagtcgc ggacatgcga tgctcatgta tcccgattgt
   363781 gaagccgtcg aaccgcaatt gaatgcgcgt gtaaggttca cagcggcaga tacaataggt
   363841 tacgtttcgc ttgcctggcc gcacggcacg ggcgcactcc cgggagcata cccggcggat
   363901 ggttcgaggt gtttccagag cgcatgcgac cgggatcggc aaaccggttt tctcaggtca
   363961 cttatgtcgc agggctcaag gccgcggcaa ggcctactgc aggagcttca gcaactccat
   364021 ggcagccgac gtagacgaag acgggttctg gccggtgacc agcttgccgt ccacgatcgt
   364081 gaagtccgcc caatcctccg ccttctcgta gcgcccaccg aggcgcttca attcgtcctc
   364141 gacgaggaac ggcacgacat ccgtcagttg aacggcctcc tcctcggaat tggtgaagcc
   364201 ggtgacgcgc cttcccttga cgatgggctc gccgtgatgc gtgacccgcg tcaggacggc
   364261 cgggccatgg cagacggccg cgaccggttt gcccgcatcg tagaagcctt cgatgagggc
   364321 gatcgaattc ctgtcttcaa cgaggtccca cataggcccg tgtccgcccg gatagaacac
   364381 cgcgtcgtag ccctcctgtc tgacgtcacc gagcttcagt gtgtttgcca atctgtcccg
   364441 cgcggcgggg tcgtccctga agcgctccat cgccgcagtc tggctcgctg gctcgtcgct
   364501 tttcggatcg atcggcggct gcccgccctt cggtgatgcc agcgtgacct ctgcccccgc
   364561 gtccttgaac acgtaatagg gtgcagcgaa ttcctccagc cagaatccgg tcggcttgcc
   364621 tgtatcgccg agccggtcat gcgaagtcag aaccatcagg attttcatgg tcattctcct
   364681 ccgttgcggc gtttccagat gcaggatcgc cggggttgcc agcctattct ccggccgtgg
   364741 ccggatattg gcgaggctcc cgtgggatta ccttcgcttc ggccatgcgc cattattgcg
   364801 agctgccgtc ttcgggtgaa tactcgttca aaggcaatca ctatcccgag gagcggcaga
   364861 ataaatggac cgcattgatg caatgaaagt cttcgtcgct gcgatcgacg agggtagcct
   364921 cgccggcgcg gcccgccgcc tcaaacgatc gccgacggcg gtgagccgtg ccctgagctt
   364981 cctggaggcg catgtagggg ttgaactcct gcaccgtacg acccgcaccc tcaagctgag
   365041 cgaagcaggc cagcgctatg cggccgcctg ccgccgggtg ctgactgacc tggaagaagc
   365101 ggacatgctt gcagggggcg agagttccgc cccccgcgga attttgacga tctctgcacc
   365161 accgatcctc ggagaggaaa tactcaggcc gatgcttgac gacttcctcg atctctaccc
   365221 gaccgtctct gcccggcttc ttctgctcga ccgattcgta aacctggtgg acgaaggtgt
   365281 ggatgttgca ctccgcatcg gccatctggc ggattcgtcg ctcatttcca cccggctcgg
   365341 gggagatgtc aggcgcgtcg ttgtcgcctc gcctggctat cttgccaatc acccccgcat
   365401 cgaagaaccg gcggacctgg ccaaacatca gatcctggca tttaccaatt tcggtcttga
   365461 gtcctggagc tttacaccgg caatgggctc gtccattccg aggacggtac agttcacgcc
   365521 gagatgcatc gtcaacagcg tgcgcgccgc cgccgcttcg gcagctgccg gacgcggtct
   365581 gacccggctt tattcctatc atgtcgcgga atatgtgagg gacgggcgcc tcgagatcgt
   365641 gcttgccggc gcggaacacc cgcccctgcc ggcacatctt ctggcaccgc agggccgaat
   365701 gtcagtgccg aaggtccgcg cctttgtcga cttcgccgcg ccgcgcctac gctctgaatt
   365761 cgcgcgcatg gcagcggagg cgggcaagcc gattataccg caggtcggat gagtgtccgt
   365821 caatctgcgg caattctccc acagtctgca ctgatctaat ttcgaatgca ccgacgccga
   365881 gggcggaggg cggacgcaga aagcggccgc tgcgattgag agaggatcat tccaatgagt
   365941 aacgaacaga aagtcgtcat cgtcaccggc gcctcgcaag ggatcggcgc cggattggtc
   366001 cgcgcctatc gagaccggaa ctaccgcgtc gtcgcgacct cgagatccat caagccgagc
   366061 ggcgacccgg atatccatac ggtcgctggc gacatcagca agccggaaac cgccgagcgg
   366121 atcgtgcgcg aggggatcga gcacttcggc cgcatcgact ctctggtgaa caatgccggc
   366181 gttttcctcg ccaagccgtt catcgagatg actcaggagg actacgagca taatctcggg
   366241 gtgaacgtgg ccgggttctt ccacatcacc cagcgcgcag ccgtggaaat gctgaagcag
   366301 ggctcaggtc atatcgtcag catcaccacc agtctggtcg accagccgat ggtcggtatg
   366361 ccctccgcac ttgcctctct gacgaagggt ggcctgaacg cggtaacccg ttcgctggcg
   366421 atggaatttt ccaggagtgg tgttcgcgtc aatgccgttt ctccgggtgt aatcaagacg
   366481 cccatgcatc cgatcgagac gcattcggct ttggccgcac tgcacccggt tggcaggatg
   366541 ggcgatatca gcgacgtcgt gggtgccgtc ctctatctcg aaaatgcagg attcatcacc
   366601 ggcgagatcc tccacgtcga cggcggccag aacgccggac gctggtaacc ggcatatccg
   366661 caacacacga acgagactcg caaaggaaac tgtaatgcct atcgtcaccg tacaagttac
   366721 ccgtgaagga agcgcgcccg gccgcaattc ggtcaccgcc gaggaaaagg cagccatcat
   366781 caagggcgtc agcgaagtgc ttctggatgt cctgaaaaag ccgttggaat ccacctatgt
   366841 ggtgatcgaa gaggtcgatc tcgacaactg gggctgggga ggccttccga cagtgcaata
   366901 ccgccggcaa cgtgtcgagg cggctaaatc ctgaagcctg atcgcttcac cgcccggtgg
   366961 agcgatccag ctgttttcgg ctacgcccga ccacgataat ttgtggtggt ggtcgatgga
   367021 gccgcgagct gctcgacttc ccgcgtcagg cgatcacgaa gcggcgatcg gatgcaaacc
   367081 gggtctgtcg cactggcatc gccggcaagc gtcatcgcct gacagcgaca gccgccgaaa
   367141 tccaccttct tgcggtcgca gttccgacag agctccggca tccagtcctc gccccgatag
   367201 gcgttgaatg cgtcgctatc gtaccagatc ttcgaaaggg cgctgtcgcg cacgttttcg
   367261 aaggagaggc tcggaatggt ttccgcggca tggcatggca gcacccgccc ggatggcgtg
   367321 atgttcaggc ccacccttcc ccatccgccc atgcaggctt tcggatactt ggaataataa
   367381 tcggccggca catagtcgat caccagaatg ccctgatagg cttcgcgcgc ttcggcgacg
   367441 gttcgggtgg cgcgttcgac ctgctcacgc gtcggcatga ggagttcctt gttccgctcg
   367501 gcccagccgt ggaactgtac ggtcgcgatc tcgacccgcc gcgccttcag cagaaacgca
   367561 agctcgatga tttcgtcgat ttcgcccatg ttctgcctgt gacagacggc gttcaacgtc
   367621 agcggaatag cagcattcgt tgcccagccg gcaacagcca tcttccgttc ataaccgccc
   367681 cggtacccac cgatccgatc ggcgctttcg ggcgagaccc cctgaatgga aagctggatg
   367741 tggtcgagcc ccgcctcggc gaggctgttc atccttgcct ctgtcaatcc cacgccagag
   367801 gtgatcagat tggtgtaaag accaagcgac cccgccgcct gcgtcaagtc cacgagatct
   367861 ctgcgcgatg ccggctcccc gccggacaaa tgcagatgca ggaccccgag atcggcggct
   367921 tgcgcgaaga cgtctaccca ttcgtcggtc gacaattctt ccttggcttg cgtcagtgcg
   367981 atgggattgg agcaataggg gcaggcgagc ggacaacgat gggtcagttc cgccagcatg
   368041 gccatcggcg gaggcacgcg tggtgccgcg acaacggcgt cggctgggcg ggcgattgtg
   368101 tcgctcattg gacgatctcc agcatgcggc ggacggaaag ctcctgcacg aacgccgtga
   368161 cgtctccggc gatctctgcg accggggcgt cgaacttctc ggcaaagccg gcggcgatat
   368221 catcaagggt cctctcgccg tcaagcgcct ggacgattgc gacggctata tcgtccaccg
   368281 ccattgcccg ttccggggca aggagcaccg tctggccgcg aaccgtatcc tcgtgcagcc
   368341 taacccctcg cgccagcttg acgacgctcg atcctgaaat cataggctga tcggccgtca
   368401 ttccgctgcc tcccgcgctc tcggctcccg cacgacccct tccgtgccat cccagcctcc
   368461 cggtggaatg cgccccggcg agacgtaagc cgaataaagc gcgtcgagct gggaccaaag
   368521 aacatccgtc ttgaacgcaa gcgccgcagc ggcggcatcc tgtttttcgc gcgtgtcggc
   368581 acggtcgagg acaaaagcca gtccgaattc gacgtcccgg ggcgcctcag ccagtctctg
   368641 gcggaaatag gccagtgccg actcgtcggc gaaggcgtaa tgctccagca gaccggcaat
   368701 gcgctccgag tggatcctgg gcgcgaaaag ctccgtcagg gaggatgcaa ccgcctcgag
   368761 aagcggcttc tcacgcacga aggacacata ggcatccacg gcaaaccggg tcgacggcag
   368821 gacgcctttg gtcgatgcga cgtaagtcgg atctagcccg accgcctcgg caagacgcag
   368881 ccagcgacgg atgccgccgc cctcttcgac gtcgccgtcg tgatcttcga tgcgggagcg
   368941 ccaggcgcgg cgcagatcgg gatcatcgca acgcgacatg aaggccgcat ctttcatggg
   369001 aatgcggctt tgataatagt aacggttgat cacccaggcg cggacctgtg tcgtcgtgca
   369061 gccgccgcta tgaagcatgg catgaaacgg atgcttgtcg tggtagcgct gcttgccgat
   369121 ctccagcaga cgggcatgga aagcttgtct gtcatctgcc gtcgtcacag ccggacctcc
   369181 attccgtcgt agccgatctc gaagccctgt gcctcgacgc gctcgcgctc gctgccggcc
   369241 cgccagatcg ggttggtgtt gttgatatgg acatagatct ttctgcggat gttcaaggta
   369301 ccgagtgcat cgaggctgcc gccttcgccg tcgatgggca tgtggcccat gcgacggccg
   369361 gtcttgcggc ccataccggt ttgaatcatc tcgtcgtcac tgtagagcgt accatcgaag
   369421 aacactgcat cggcatttcg caggcgcgcg gcgagcgcat ccgtcatcac ggcgcaaccg
   369481 ggaacgtagt aaacgcgctt gcctgcagcg gccaattcga cgccgaccgt atgctcgccc
   369541 tcaaggccca ggtccggctc gccattctcg agaaagagcg gcactttccc agggacggcg
   369601 aagagccgtg ctccgagccc ttggagcggc gagaacgtct cctcgatctc gatggtcctt
   369661 ttcgaaacca gttccgggtc gaggacctga aagaccggat tgtcggcgac gattctgccg
   369721 actgcgccgg tcgaaaacaa ggcgaatgcc tgcttctccc gcaggacgag aagtcctgcc
   369781 agatgatcga tgtcgccatt cgtcaacact acgctttcga tagggctgtg gcgcagacgg
   369841 cgcggctgca gcgggcgatt ggcgtgaatt tgctggcgga tgtccgggga ggcattgaac
   369901 acggcccagg cctcgccatc gaggctcact gcaagcgagg actgggtctg tggtttgaga
   369961 ccggagcccg ggtcgcgcgc catcgcgcag ttgggacagc cgcaattcca ttgagggaga
   370021 ccgccgccgg cggcggcccc caagacaagt attcgaagat cgggcgtttt gttcaccgga
   370081 atacctgatg ctttaccgat cctcgtcgcg ctggccgtta gaagaggatc ggttcatccc
   370141 cgtccgcagg agcgtagcgg gtaatttcca tagcgcagct gacttcgata aattttggtt
   370201 tatgccaggc cataattcct ccattcgccc ttgggggtcg ttgtgctcgc tcccgttcca
   370261 gcaggcgccc ttaccgtcgg gggcgggcat gaaccaaaca gggcttttgt cggcccatgc
   370321 ttgggtgaca cgtccggacc ggcatttcgc tgttccggca gagcccggcg gcgccgtagc
   370381 cgggctttca ggcatcgtgc aatctcctct tggggtccat ggtagcaagc cgggcagcac
   370441 cccacaatta cgacctaggt gttggtcgcg gtcctcccgg ccgcaccccg tccaactcct
   370501 gaataccgat cgggttcaca cgctcgagcg gatacgcgct gacatcatcg tgatcgggag
   370561 ccttccccgt ccaaatggaa ggcgctagcc gaacgcgttg gccgggtatg gcttgctgac
   370621 aacgggcaga tagcgagcgc ccgacgacag cacgaattgt tcgaaagcct gcattgccgg
   370681 tgtggccgca cggtccaggc gtgaaaccgt gaaccattgc cggcgtatag gcgtgtcgat
   370741 gacgtcgagt attaccagcc gtccgagctt cacctcctgc tcgatcgtgt gggccgagat
   370801 gaaggcaatc ccaagaccgg caatgaccgc ttgcttgatc gtctcgttcg aagcgatctc
   370861 ggttccgagt tcctccagtt cgtgcggggt atcgctcaga aagatctcga gcgaaatacg
   370921 tgtccccgat cctttttcac gcaccaggaa ctgctcccgc gcgatccgct cccgcgaaat
   370981 ctccagcacg cctgcgagcg ggtgtccggc gggtgctatg aagaccagag gatgatcgcc
   371041 gaatacctgc gcgcgcacct cgaaatcacg cggcggccgc cccatcagcg cgatgtcgat
   371101 ctcgtggtcc cgcagcttgg ctatgatctc ggcgcggttg ccgatgaata gatttatctc
   371161 gacggctgga acctggtcgc ggaaagcggc gatcagttgc ggcgcgaaat acttgccggt
   371221 cgacacgacc ccgaggcgca aacgtccggt tctgagccca ctgatggcac cgatcgaatc
   371281 ctcaagggcg gccaggctgt cctcaaccgc gcgtgccgcc tcaagaaagg caaggccata
   371341 ggccgtcggc accatgccgc cgcgcgtccg gtcgaagagt gcaacgccgg tgtcccgttc
   371401 gagatgctga atctgcaggg tgagcgccgg tccggtcaat ccaagtgctt cggcggcaag
   371461 gttgatcttt cccaaccggc agacggcttc aacggtacgg agctggcgga gggacacgtt
   371521 gcgcatgaag tcacaagtaa ataaaaatta cttatgaagt caaatgaata aattttacaa
   371581 actcgccttt tgcgccatcc tttcccggac atcgtggagg agacatcatg tcaggcgcaa
   371641 ctttagaggc ataccttgct tcatgcacga cccatggcga cgagctctca cgggacgtcg
   371701 ccgccgtgat ccagagactg gcaaaggctg ccctcgacat tcgcaaactc gttaatcagg
   371761 gagcgctcgg caccgtcttc aatggaatgc atagcggcag caacacggat ggcgatgttc
   371821 agaaggacct ggacatcctg tgcgacgacc agttcctctc gtgtctgcaa ggcgccccgg
   371881 tcgcatgcta cgcctcggaa gaactcgaaa atccagttct gctcgatccg gctgcacgcc
   371941 tcgctgttgc catcgatccg ctcgacggct catcgaacat cgacaacaac atctccatcg
   372001 gaacgatatt ttccgtgctt cccgccgcca aggggccgga cgttgacccc tcccagtcct
   372061 tcctgcaacc cggaaaccgg caactggcgg cgggcttctt cgtttacggg ccgcaaaccg
   372121 ctcttgtgct ttcgctcggt agaggcacgg agattttcat cttctccagt cggctcggat
   372181 gttttgtcga tgcgtacaaa tcggtcggca ttccggatcg cgcgaacgaa ttcgccatta
   372241 acatgtccaa ctaccgccat tgggaagaag cgatccggct ctatgtcgac gactgcctgg
   372301 ccggctccga ggggccgcgg gagcgggact tcaacatgcg ctggattgcc tcgctcgtcg
   372361 ccgaagccta tcggatcctc gtccgcggcg ggatcttcct ctaccccgcc gacagccgca
   372421 agggctacag ccatggccgg atacggctgg tctacgaggc caacccgatc gccttcatcg
   372481 tagagaatgc gggcggctcg gccacgacat ccgtcgaccg catactcgat ctcgttccag
   372541 aaagcctgca ccagcgcgtg ccgctggttt tcggttcacg ccgcgaggtg gcgcgcatca
   372601 cccgttatca cgtcgatccg aacatgatcg gcgaacgcgc tccgctcttc ggcaagcgcg
   372661 gtttgttccg ggcctgagga gggcaatatg tcggccaaat acccaatcat ctccatcaca
   372721 ggttcgtccg gcgccggcac cacgaccgtc aaggacacgt tcgagaagat attcaagcgc
   372781 gaaaacatct cggcatcctt tatcgagggc gatgccttcc accgctacga ccgagaaacc
   372841 atgcgcagca agatcgcgga ggaaaaagcc cgaggcgtcg acttcacgca tttctccgcc
   372901 gaggcgaacg aactggagat cctcgaaagc gtctttgccg agtacggcag gcgtggcgtc
   372961 gggcgcaccc gtcactatgt gcacgacgat gccgaggcag tgaaattcgg ttcggacccc
   373021 ggcacgttca cggattggga agagttcaga gacagcgatc tcctcttcta tgaaggcctg
   373081 catggctgcg ccgtcaccga caccatcaac ctcgcccagc attgcgatct gaagatcgga
   373141 gtggtccccg tgatcaatct cgaatggatc cagaagatcc atagagacaa ggctacccgc
   373201 ggttattcca ccgaggccgt gaccgacacc atcctgcggc gcatgcccga ctatgtgcac
   373261 tacatctgcc cgcagttctc cctgacggac atcaacttcc aacgcgtacc gatcgtcgac
   373321 acatccaatc ccttcatcgc ccgctggatc ccgacgccgg ccgaatccat cctggtcatc
   373381 cgttttgcca agccgcaaag catcgatttc ccctacctgc tgtcgatgct gcacaacagc
   373441 tacatgtcgc gcgccaattc catcgtggtg ccgggcgaca agctcgatct agccatgcag
   373501 ctgatcttca ccccgctcat tcacaagctg ctcgagcgca agcaccgcat gtcgtgagga
   373561 ggacatcatg aatgtttcgc agcagatcga accccgcgcc gccgcctcgg agcgcaacat
   373621 ggccgacgcc atccggtttc tttccatgga tgccgtcgag aaggccaatt ccggtcatcc
   373681 gggcatgccg atgggcatgg cggacgcggt taccgtgctc ttcaaccgct tcatcagaat
   373741 cgatccgtcg ctccccgact ggcccgaccg cgaccgtttc gtgctttcgg ccggccatgg
   373801 ctcgatgctg ctctattccc tccatcacct catcggcttt gcggacatgc cgatggccga
   373861 gctttcgtcc ttccggcaac tcggctcgaa aacggccggc catcccgaat acggccatgc
   373921 cctcggcatc gagaccacca ccggcccgct gggccagggg atctcgaccg ctgtcgggat
   373981 ggcgatggcc gaacagatga tggcctcccg gttcggcagt gctctgtgca accacttcac
   374041 ctatgtcgta gccggcgacg gctgccttca ggaaggcatc agccacgagg ctatcgacct
   374101 tgccggacat ttaaagctgc gcaagctggt cgtgctgtgg gacgacaacc gaatatcgat
   374161 cgacggatcg acggatctct ctacctcgat gaaccagctc gcgcgtttcc gcgccgccag
   374221 ctgggacgcc caagccgtcg atggccacga cccggaagcg gttgcgaaag ccctggaaag
   374281 agcacgccgg acccgcaagc cgtcgctgat cgcctgccgc acccggatcg gcaagggtgc
   374341 agccagcatg gaaggctcgc acaaaaccca cggcgcggcg ctcggcgaca aggaaatcgc
   374401 agccacacgc gaaaaacttg gctggccgca tccgcccttc ttcgttccgc ctgagataag
   374461 ggctgcctgg gcaaaggtgg cggctcgagg tcgcacggct cgcgaggcct gggatatccg
   374521 cctcgacgcc tcgcgctcga aaaagcgcta cgagcagacc ataaggcggc agtttgacgg
   374581 cgaactcggc gatctgcttg caaaattccg gagcgcgcat cgcacaaggg ctacgaaagt
   374641 tgcgacgcgt caggcctcgc agatggcgct ggaggtcata aacggcgcga ccgctttgac
   374701 gatcggcggc tcggccgacc tgaccggctc caacctgacg atgacctcgc agacccagcc
   374761 catctcgccg ggcaatttca agggccgtta tctgcattac ggcatccgcg agcacggcat
   374821 ggcggccgct atgaacggca tcgcgcttca tggcggcttc atcccctatg gcggcacttt
   374881 cctggtcttc tccgactatg cccgcggtgc gatgcgcctc tcggccctga tgggcctgcc
   374941 cgtcatttac gtgctgacgc atgattccat cgggctcggc gaggacggac cgacccacca
   375001 gccggtcgag catctggcca tgctgcgcgc cacgcccaac ctcaacgttt tccggccggc
   375061 cgacatcatc gagacggcag aatgctggga gatcgcgctt ggcgagaaga atacgccgag
   375121 cgtcctcgcc ctttcgcgtc aggccctgcc gatgctgcgc cggacggaag gcaacgagaa
   375181 ccagtcggcg ctcggggcgt atgttctgag ggaagcgcgc ggcaaccggg acatcacgat
   375241 ccttgccacg ggatccgaag tcgagatcgc cgtcgctgcc gccgagcgcc tgcaggccga
   375301 ggaaggcatc gcggcggcag tggtctccat gccctgctgg gagaagttcg aggttcagga
   375361 ccttgcctat cggaggaagg tcctcggcga cgcgccccgc atcgccatcg aggcggcggg
   375421 ccggctcggc tgggaccgat ggatggggcc ggacggtgcc ttcgtcggca tgaccggctt
   375481 tggtgcctcg gcaccggcag gcgacctcta ccggcatttc ggcattaccg ccgaccatgt
   375541 cgtcgcagaa gccctggagc ttctccgccg cgcatactcg gaaactctgc ccataggtgc
   375601 ccggatcggt ccgcacccat ccgcacacac cgtcagatca tcgcaggagg catgacaatg
   375661 gcccgcatca cgctccgcca attgctcgat cacgccgccg aacgcagcta tggcgtgccg
   375721 gcattcaaca tcaacaacat ggaacagggg ctggcgatca tggaggcggc acgcgcctgc
   375781 gatgcgcctg tgatccttca ggtctcgcgc ggcgcccgtt cctacgccaa cgacatcatg
   375841 cttgccaaga tgatggaagc gctcgaagtg atgtatccgg acatcccgct ctgcatccat
   375901 caggatcacg gcaacaatgt cgcgacctgc ctcaccgcga tccagcacgg cttcacctcc
   375961 gtgatgatgg acggttcgct gaaggaggat gcgaagacgc ctgcagacta cgcctataac
   376021 gccatgatca cgacggaagt gagccgcctc gcgcacatgg tcggcgcctc ggtcgaaggc
   376081 gaactcggct gcctcggatc gcttgagacc ggccatggcg aggcggagga cggtcacggc
   376141 ttcgaaggcg cgctcgaccg ttcgcaactc ctgaccgatc cggacgaagc cgctcgcttc
   376201 gtcgccgaaa ccggggtcga tgcgctggcg gtcgcaatcg gcacctcgca cggcgcctat
   376261 aagttcaccc gcaagccgac cggcgaagtt ctcgccatgg acgtgatcga aaagattcat
   376321 gagcgcctgc cggatacgca tatcgtcatg cacggctcct cctccgtgcc gcaggaatgg
   376381 caggacgtct tcaatgctca tggcggtgaa atgcgggaga catacggcgt gccggtcgaa
   376441 gagatcgtac ggggcattcg cttcggcgtg cgaaaggtca atatcgacac ggatctgcgc
   376501 ctggcggcgg ccgccgcctt tcgccgcgtc gccgacacga gccgcaccga attcgacccg
   376561 cgcaagtttt tgaaacccgc catggacgca atgtcggcgg tctgcaaggc ccggttcgag
   376621 gccttcggca cggccggaaa cgcgtcccgc atcaaggtcg tgcctatggc ggagatggct
   376681 cgccgctatg caagcggctc cctgaaaccc caggcgaagc gggctgaagc cgcctgacca
   376741 cttccattca gagaaaggaa ccctgttatg aacgctgatg caaagacaga gatcaagggc
   376801 cgggaacgct ataaggccgg cgtgcttaaa tacgcgcaga tgggctactg gaacggagac
   376861 tacgaaccga aggacaccga tctgatcgca ctcttccgga tcacgccgca ggatggcgtc
   376921 gatccgatcg aagcggccgc cgccgttgcc ggcgaaagtt cgacagccac ctggaccgtc
   376981 gtctggacgg atcgcctcac ggcttgcgat caatatcgcg ccaaggctta ccgggtggat
   377041 ccggtaccgg gaacgccagg ccaatatttc tgctacgtcg cctacgatct gatcctgttc
   377101 gaggaagggt cgatcgccaa cctgaccgcg tccatcatcg gcaacgtctt ctcgttcaag
   377161 ccgctgaagg cggcaagact cgaggacatg cgcctgcccg tcgcctatgt gaagaccttc
   377221 aagggtccac cgacgggcat cgtggtcgag cgtgagcggc tggacaagtt cggcaaaccg
   377281 ttgctcggcg ccacgaccaa gccgaagctc gggctttcgg gaaagaatta cggccgcgtc
   377341 gtctatgagg gcctgaaggg cggtctcgac ttcatgaagg acgacgagaa catcaattcg
   377401 cagcccttca tgcattggcg cgaccggtac ctttactgca tggaggccgt caaccacgcc
   377461 tcggccgtca ccggcgaggt caaggggcac tacctcaacg tcaccgccgg caccatggag
   377521 gaaatgtacc ggcgtgccga attcgcaaag gagctcggct ccgtcatcgt tatggtcgat
   377581 ctcatcatcg gctggactgc aattcagtcg atgtcggaat ggtgccggca gaatgacatg
   377641 atcctgcaca tgcaccgggc cggtcacggc acctatacgc ggcagaagaa ccacggcatt
   377701 tcgttccgcg tcatcgccaa atggctgcgg ctcgccggcg tcgatcacct tcatgcgggc
   377761 acggccgtcg gcaagctcga aggcgacccg ttgactgtgc agggttacta caatgtctgc
   377821 cgcgaaatga agaacgcggt cgatcttccg cgcggcctct tcttcgagca ggactgggcc
   377881 gatctcaaga aggtcttgcc ggtggcgtcg ggcggtatcc atgctggcca gatgcaccag
   377941 ctgctggacc ttttcggcga cgacgtcgtg ctgcagttcg gcggcggcac gatcgggcat
   378001 cccatgggca tccaggcagg ggccaccgct aaccgggttg cgctggaagc catggtgcta
   378061 gctcgaaacg agggccgcga catagcccat gaaggccctg agatcctgcg ggcggcagcc
   378121 aaatggtgca agccgctgga agcggccctc gatacctggg gcaatatcag cttcaactac
   378181 accccgaccg acacgtcgga tttcgtgccg agcgtaaccg cggcctgacg gtaaagaaga
   378241 ggagagacga catgcgtatc acccagggat gcttctcgtt cctgccggac ctgacggacg
   378301 agcagataac ggctcaggtg gaatattgcc tcggaagggg ctgggctatc ggcgtcgaat
   378361 acaccgacga cccgcatccc cgtaacacct attgggaaat gtggggcaat ccgatgttcg
   378421 acctgaggga cgcaaaaggc gtgatgatgg aggtggagga ttgccgcaag gctcatcccc
   378481 aggactatat ccgactgaac gccttcgatt ccagccgcgg ccttgagacg gtgacgatgt
   378541 ccttcatcgt caaccgtccc gagaacgaac cgagcctcag gatgacccga acggagagcg
   378601 acggccgcag ccagcactat acgtgggaaa cacagcgata ggaggcacga catgctgatg
   378661 ccggatgctc caacaactac cgaaagcctg ccgacttcgg tcgacctcgc tgaggaatac
   378721 caagcctccg gcgtcgccga gatcctcgac gaactggacc gggaactcgt aggattgaaa
   378781 cccgtcaagc agcgcatccg cgagacggct gccctgcttc tggtcgagcg ggctcgccgg
   378841 gcaatgggcc tcagccatga gccgccatcg ctgcatatga gcttcacggg caatcccgga
   378901 accggcaaga ccaccgtggc gctgcgcatg gccaacctgc tgcacaggct cggctacatc
   378961 cgcaagggcc atctggtttc ggtgacccgg gatgatctgg tcggccagta tatcggccac
   379021 accgcaccca agaccaagga gatcctcaag aaggcgatgg ggggcgtgct gttcatcgac
   379081 gaggcctatt acctctaccg cccggacaat gaacgcgact acgggcagga agcgatcgag
   379141 atccttctgc aggtcatgga gaacaatcgc gacgacctgg tcgtcattct tgccggctac
   379201 gccgatcgca tggatcggtt cttcgagagc aatccgggtt tccgctcgcg catcgcgcac
   379261 cacatcgatt tccccgacta tgataacggc gaactgcttt ccatcgccga aagcatgctc
   379321 agccgtcagg gatatcgttt cgatgccaag gcgtcggcgg tgatgggcga ttacatcgaa
   379381 cgccgccggt gccagccgca tttcgccaat gcgcgctcca tccgcaacgc gctcgaccgc
   379441 gcccggctgc gacaggcaaa ccgcctcttc gaggaaagcg ccggacccgt cgacgccgag
   379501 caactttcga ccatcaccgc tcgggacatt tcggcaagcc gcgtgttcgc cgccggggag
   379561 cccagccata aggagacaac gccatgaatg agacgaccat catagcccct tcggttctgt
   379621 cggccgactt ctcgcggctc ggcgaagagg tcgaagcggt gtgccgggcc ggtgcggact
   379681 ggattcatct cgacgtcatg gacgggcatt tcgtgcccaa catcaccttc ggcccgccgg
   379741 tcatcaaggc actgcgggac cgcacggaca aggtgttcga ctgccatctg atgatcgcac
   379801 cgcccacacc ctatctcggt gctttcgcct gcgccggatg cgatatcatc accgtgcacg
   379861 cggaagcgac cacgcatctc gatcgaacgc tgcaggccat ccgcgatgtc ggctgcaagg
   379921 cgggcgtatc cctcaaccct tcgacgcccg aaagcgtgat cgaatacgtg ctggaccggc
   379981 tggacctcgt cctcctgatg acggtcaatc cgggtttcgg gggtcaggat ttcattccgg
   380041 ccgtaatcga gaaggtgcgg cgcgtgaagt cgctgatcgg caatcgtccg atccacatcg
   380101 agatcgacgg aggcgtgacg ccggaaaccg cgccgctggt tgccgcggcc ggtgcggatg
   380161 tgctcgttgc cggctcggcg gttttcaagg gaggcagcga ggagcactac gccaggaaca
   380221 tcacagccat tcgcgccgcc tcggacggcg ccatcaggaa agcagcctaa gccatggccg
   380281 ctacaccacc cctttgcgat ttcggccggc cggcgatcga tgccaggctt ccgggcgtcg
   380341 atggctcctc gcactccata ttcgatcagg ccggcccgaa ggggctcgtg cttgccttca
   380401 tctgcaatca ctgcccctac gtcaaagcag tcattgcccg gatcgtccgg gacgcgagcg
   380461 accttagggc tcatggcgtc ggctttgtgg cgatcaactc caacgactcc ggcaactatc
   380521 cgcaggactc gttcgagaac atgaagcgtt tcgcttcgca gaacgccctc ccctttccct
   380581 atctccacga cgaagaccaa tccgtcgcca aagcctacgg cgccgtctgc acacccgact
   380641 tcttcggttt caacaaggat atgagattgc aatatcgcgg tcggctggac gcttcgcgca
   380701 aggaaatcgg ccctgccgat ctgagacgcg acctgtacga agccatggtc atggtggcga
   380761 tgttcggcaa gggaccggcg gagcagcagc cctccatagg ctgtaccatc aagtggaagg
   380821 tttcggcgtt tcaggtttga cctgattcgt tcgccgttgc gccgtaagac gacgttcgct
   380881 tgcagacatg cggggcgcgc gccatctttc acccactgca cggctcttga gacgtctcaa
   380941 gggactgcag gttctcctcc gtccctcatt tctgtgctcg tcacggaaat ccagcagcgc
   381001 cgcatctgcg gtgcggggag agtgtgccca aggacttggc ctggctggca actgtgtttg
   381061 tcaggtggtt cgtcggaagg ttgttttgtc cctgatgatg gcgtttgcga tggcgagcaa
   381121 tttgcgggca agcgcaatga tgacgacctt gaagggcttg cctgcctcct tcatttggtc
   381181 agcatgggac ttaaaagcac ggggcatacg gctggctgtg agcgccgcca tgtagagcgc
   381241 gtcacgtatc cgcttgcgac cgccgcgtat atgccgcttt ccccgtgacg tgccgctgtc
   381301 gacattgaag ggcgcaagac cggcaagggc tgcaatcgcc ttggccgaac gattgccgag
   381361 ttctggcata tgcgcgatca gggtcaatgc ggccacgggg ccgatgccgg gaatggaacg
   381421 cagccttgcc tcttgttctt gcaaggtctt ctcggccttc agaacatcac ggcatgccat
   381481 ttcgatgcgc gcaacctccg cgtcgagcca agccatatgg ctttcagcac tgtcacgctc
   381541 gatcccctcg gtctcatgaa ggcgtgtccg ctcttgctgg cgcatggcca cgagctggtc
   381601 acgccgcgtg tgaaggcggg cgagcacgtg gcgggcggga tcgtcaggcg cctgagttga
   381661 gagtggcagg ctttgaccca tccgggcaag cagacgtgca tcgatcgcat ccgtcttggc
   381721 aagaaggccg atcgccttgg caaagtcgcg ggcgcgggca ggattgacgc gggaataggg
   381781 caactccggg gtctccaggg ctatgcgcaa ctgccgatcg taacgcccgg tcgcctcaaa
   381841 gacgatatga acgcctctgc catcaaggcc gtcgagccac gcggaaattg cggccggagt
   381901 gttgtcgata cggaaatggc gctcaaggcc gctgtcgaaa aaatctagat gcgcttttgc
   381961 aatatcgcat ccgatgacat caggatgtat catgggactg ccttatcctg tgatgcgagg
   382021 tccgctgtga cggcctccgt caactgttca ggttagggat tcgaagcggg cggaggacca
   382081 gagccagcac acggtcttta aagaccagga ttccgacggc cttccgcccg cacccatata
   382141 agcacagttt cgacacacag gattcctgtg acgagcacag gaatgagatc ggagggcacc
   382201 cgcgacagac aaggcgcggg aggaagggtc ggaatgcccg ctctatttcg tgaccgaaag
   382261 tcgtctacca tgctcaggcg cgaacacaga aacacctcaa accccgcccg ttgaaatgcc
   382321 tcttcaacaa gaggcgacgg gcggggtccg agggaggaga cggtcggctg gtggtgcgag
   382381 tccccagtag ctgcagcagg tcaggccggc agcgcgccgg tctgtttggc gatgtgggtt
   382441 gctatcgcgt ccatcaaagg cggtgacaac gcgtcatagg gttcaagccc gatttccttc
   382501 aggcgctcgc gtatctccgg catcctttcc gggttcacgc cgctttctat gatcgacgag
   382561 acgaaggccg cgaattcggg tggcgaccag cccgtttcgt tgctgagctc ggtatgaacg
   382621 aaatcgagcc cgtaaaacgg gtgcttggtg ttctcgatcc ggccatacat atgcgttccg
   382681 caatcccggc aggcatagcg ctggatcgtc gcgttcgggt cgacgacctg cagtttttcg
   382741 gatcccgagg tgacgtttac cttgtctcgg ctgacgaccg caatctgcgc aaagatggcg
   382801 ccctccggct tccagcattt ggtgcagccg caggcatggt tatgcgccgt ctgcgcaccg
   382861 atctccacgg tcaccggatt gctggcgcat cggcacttca gcgtgccacc ggcaaagccc
   382921 ggactggcgg gcggaaagcc gttatcgatg gacggatgta gctttagcat tggttcctcc
   382981 tcggcttgaa cgtccttcgt tcacaagcag gatcagtgca aaagcggctc gcggcaatat
   383041 agcggaaagt gtcggttttc gggcgtggag cccttaaaac aaagcaatct cagcccttcg
   383101 accgaagcat ggctcgggcg ggattgtagc cccacagggc cgcgagcatg aacaggatga
   383161 agcacgtgcc gacccagacg agtgcggtca ggtcgagctc gccataaagc gcgaatcgta
   383221 tcagttcgac cgcgtaggta aacggattca gggcgcagat atcgcgcaac aggggagaac
   383281 tctccgccat cttccatagc gggtaaagtg ccgaggacag gaagaacatc ggaaagatca
   383341 cgaagttcat gacaccggcg aagttctcga gttgccggac cgtcgaggat atcagcaggc
   383401 cgaaagcgcc aagcatcaag ccgctgatga ccagggcagg aagcaccgcg acataaccga
   383461 cgggcggtac ggtaatgccg gtcagcgccg ctatacccag gaagaccgcc acctgcagaa
   383521 tggacacgat cacaccggcc aggagcttag agaacagcag ccaccagcgc ggcaggggcg
   383581 aggtcagcag gaggcgcatg gatcccatct cctggtcata gaccagcgcc agcgacgatt
   383641 gcatgccgtt gaagagctgg atcatgccgc agagccccgg aaggatatag acttcatagg
   383701 taatataagt ctgatagggc gggatgatcg acacgccaag cgctgcgcgg aaaccggcgg
   383761 caaagacgat cagccagacg agcggtcgca cgagtgctgc cagaaaacgt ccgcgctggc
   383821 gaacgaagcg caggttttcg cgggtgacga ctgcagaaag ggcgatcagc catgccttca
   383881 tgtcacgatc tcccggtctt ccgccgtcat cgagaggaac gctttggcga gcccctgccc
   383941 gcccgcaagt tccccggccc tgccatcgct cagaaccttg ccacgatgca gaacgacgac
   384001 ctggtccgtc ggccggatct cgtccacaag atgcgttgcc cagaggaccg aaagcccgct
   384061 ctcggcgagc tgatggacat ggtcggtgat tgccagacgg gaggcggcgt ccagtccgac
   384121 cgtcggctca tcgagcagca atatctgcgg cccgtggatc agtgccctcg cgatctccat
   384181 tcgccgccgg tgaccgccgt tcaaggcacg cacctgctcg tcggctcgct cggccatgcc
   384241 gagctgtgtc agcgcggctt cgatcgccac agcggctggc ctcccggaca agccatggag
   384301 cccggcgaaa taacgcaggt tacggcgcac cgacatgtcg aggtcgaggg tcggctgctg
   384361 gaacaccacg ccgatacgcg cgagcgccgc acgcggctcg cgcgcgatgt cgaagccggc
   384421 cacgccaatc ttgccctctc ctgtcgcgag cagccgtgtg agcagagcga acaacgtcga
   384481 tttgccggcg ccgttcggcc cgagcagggc gcagaaccgc ccgttttcta cggagaaact
   384541 gacatcgtgt agtgccttgg actttccgta gctatagctg acatggctga cctcaagccc
   384601 gatcatgatg tccttcccag ccgtccgatg cgggttttgc cgcaaattcc tcgatgatcg
   384661 ttgccggttt tccggcgagg cggaggcagc gccgggcaag ccgtcgcgcc tcggcctcgg
   384721 aatgggtcac gagaatgacg gcaggggcgg tttccgcgat cagggcctcg gtcaacgaca
   384781 acatatcctc ggccattgcg ggatcgagcg acacataggg ctcgtccatg acgagaagtt
   384841 ccggccttcc ggcaaaggcg cgggcgagcg ccagccgtcg ctgctgcccg agggacagct
   384901 ggcctgggaa aagcccggcc ttgtcggcga tgccggtccg ctccagtgcc gataaagctg
   384961 cctgcgttcc gagttgcgga tgcaccaatg tcaggttctc gacgacgctt cgccacggca
   385021 ggagaacagg ctcctggaaa accatggcga tcttttccgg ccgggtaatt ttgccttcga
   385081 aaccggtgtc gattccgacg atgagccgga gcagcgtcga tttgccgatg cccgaaggac
   385141 cgagaatggc aacggtctcg cccgtctcca tctcgaaacg gatagcccgc agcacctcct
   385201 cttccccgaa tgccttacgt ctgacatcga ccttgatcac gccgtcctcc agcgtcgcac
   385261 acggcgttcg gccggctgca ggaagagagc ctccaccagc agcatcacgc cgatgaatga
   385321 aagcgcatag acgagcacca tggcaacgtt gaaaagctgg aaatagaaat ggatctggaa
   385381 gccgatgccg ctggagcggc cgagaaactc caccaccagt acgatcttcc atatcaccgc
   385441 gatgccggca cgggcagagg cagcaatgaa aggcgcaagc tggggcatga tcacgtggcg
   385501 cagccgcgcg agcggccgca tgcggtagac tgcggccatg gagtcgaggt tcggatcgag
   385561 tgcccgcgtg ccctcgcgca ggagcgttgc gacattgggg atcttgttga gcacaactgc
   385621 ggtgatggcg gcggtctcgt tcagaccgat ccagatgtag cacaggacga tcagcacgag
   385681 tgccggcagg ttgagaaaca cgacgagcca tggatcgagc caccgatcga cactggcgaa
   385741 gcgccccatg agaaagccga ccgccacgcc gatgatcatt gccggcacga atgcgcatac
   385801 cacgcgccat aaggtcatcc cgaggtgata gggcaaggcg ccggagccaa gcgcctgcag
   385861 gaaaggcgtc caaagggccc agggctgcgg caggacggac gcgtccgcag tcagggcggc
   385921 ggccgctatc cacaagagca acagcagccc cagcgacaat gcgcgcacca aggcaggatg
   385981 ttgcagcgtc ttattcaagg tgcaggaaca atccattagg caggcttgtc gccttgccga
   386041 cgagttcttc tccgccgagt tccgccatca gccgcagaaa ccggtcagcc gccgcctcgt
   386101 cgatcggctt gccgctcgga atgccggcac gatagccgtc acgcagcgca acgaattcag
   386161 catcgtctgc cgcgttcatc ttgtcccgca atgcccccca cacctcgtca tcgctgcgca
   386221 gcagatcctt ggccgcgcga gaggccttgt aaagcccttt cacaatatcc ggatgggtcg
   386281 cggcatattc gcccttcaac acatagccga gcagcggcgt atcgggatcg agcttgagcg
   386341 ccgctgcagc gtctgaaacc gagatcagct cgtgcatgcc tttggccctc atcttcgcga
   386401 ggaagtgcca gaaattgatg gtacctgccg tctcgccgga aagcgccgac ttgaagatca
   386461 gcggcggcgc gccgaatacc tgctcggttt cggctgcaag gtccatgcca tgctgctgct
   386521 tggcataggc gcgcaggatc aaccagctct tgtcgagcgg acctccggcg atgccgattt
   386581 tcttgccggc aaggtccggc agcgccttga tgtcgctgtc atccttgacc atcaggccgc
   386641 cgactgcccg cgaataagga ataaagacat agtctttgcc ggcagcacgc tggttggcca
   386701 cccagatcca gtcggccacc atcgtgtcgg cctcgccgcc ctcgaaggcg acgcgcgtcg
   386761 cgccgttgtc cgcataatcc tggaccacca gctcgaagcc gttcgcgcga tcgaattcgt
   386821 gggtcttgat cgtggagatt tcccagttga cggtgcccga ggccagcatg gctgcgcgca
   386881 actgcggcag ttcctcggcc agggcgaagg tcggccccaa ggcaagcagg caagcggcga
   386941 agaggcaaac ggctaattgc tcaaaaacct tcattgcttc ctcccgaaaa actgtcgccc
   387001 tggttccgct gtccagcaaa cttctcgtgc gggcggctca ctgaatggag atcgacacct
   387061 tctggctatc gctggaagtc tccggaatcc tcacctcgta tgttcccggc ttgatggcga
   387121 tgaaggacag ggtggcggtc cccgcctcgt cgaattccag gctgtcgatc gccatgggcc
   387181 gcacttctat gccgttgacg acgatctcgt tcatccagat ggcgcgaaag aacggcgctc
   387241 cagtgatcgc cagctccgcc gatccgtccg ccgtgatctg catttcatag tatgcgcctg
   387301 actgcagcgt aatggcaccc ttccccaacg gttttccgga ggcgagcgta atctcgatcg
   387361 gctccccccg attgcatttg gcaagcagcc cggcaaagcc catatcggcg caaagcggcg
   387421 cggccgcggc cggaccagcg agaaagagcg tggcgagcgc tgcaacaaaa gatctatgca
   387481 cgatgaacat cctccctatc gttattgccc gtggttccgc ctcaattcgg tgcaaccacc
   387541 acaccccaag gctgctcgcc cacctgaacc gactggataa ccttttccgc cttcacgtcg
   387601 atgatactga cgtcgttgga attgccgttg gtggtgatca ggaattcctc gcccggcgtg
   387661 aatgccatct gccacacccg ctgccctaca agcagatagt cgagcacctc gtcggtctcc
   387721 ccatcgatca ccgcgacgcg gttcgcgggc cctagcgcca cgaaaatacg tgagccgtcc
   387781 ttggtcgcct tgacaccgac cggctgcagc cattccggca ggacgccggg cacttcaaat
   387841 gtgatcttcc tggtaatctt cggctcggcc gccgacacgt cgatcacgga aacggtgccg
   387901 ccgatttccg aactcacgta aagcttcttg ccgtcggcag tgaattccgc atagcgcggc
   387961 cgctggtcca cgagcacgtt gtgcacgatc ttgtaggtcg cggcgtcgat gaagtgcgcc
   388021 atattggtgg tttcggacgt gttgatgatc gtctttgcat ccgggctgac cgctacgccc
   388081 tccggttcga cgccgacagg cacctcggcc agcacctggc gggtcttgac gtccacgacg
   388141 gttaccagat tgtcgtcctc attggcgatg tagagcggat tgcctgacgg cgcgagagcg
   388201 aagagctccg ggtccgggcc agagggcagc gtgtgcagtt ccttataggt ctcgggatcg
   388261 aagacgcgaa cagtgtcgtc gtccgaggcg catacgtaaa gctccttgcc atccgggctg
   388321 atggtgatgc cgcgcggcct gttgcctgcc ggaaacgtgg cgatcacttt ccagctttgg
   388381 ctgtcgagca cggtgacgtt gttgccccgt tcgttgctca cgaagacctt gttggcctcg
   388441 gcagaaccgg caaacatcag aacggcgggc atcagaacgg cgggcatcag aacggcgggc
   388501 aaaagcgcca ttgcggattt gagcatctta tcctccaaag gcctggcagg cggtttcggg
   388561 cgcatcgatg cccagcgtgt cgagcggcga atgctgatgc aggtaaccgt cctgcggaga
   388621 aacggagacc gtcacccggc cttcggtcag aaggaccggc tgccgcagct gcccgttcca
   388681 ggtgcggaag gtcagcttct gacccttgaa cgcggccagt tcgaagtcct tcgaaagggc
   388741 ataggcccgc acggttgcgg gatcggcctt gccggagcgg gtcaccgcct ccccgatcac
   388801 ccgcatggca agccacgcct gatagtcttc ctcgcgcatg taacggccgg taagcttctc
   388861 aaagcggcgc tggaactggg tcgcgcccca cgcctcgtgg gcgggatgcc aggagacagg
   388921 gcgaagtccg gccgatccgg cgatgggcct cggatcccag ctgtggtaag gcagataggg
   388981 cgcgaagacg cctgcttcgt cggccgcgac gatgacgtca tagggctcgg cttcctgtgt
   389041 gaagacggga atctgctttt gcaccatgac atggccggta tccgttcgcc ggctgccgcc
   389101 ggtatcgacg aattcgcgct cttctacgat cttcgcgccg aatttggcgg ccgatttgcg
   389161 gtagctttcg gccagcagcc tgtcttccgg atgcgagccg tggatcagca ggatacgagg
   389221 ccatttcttc cacatcagga actgcacgat actgtcgctg agcatcgagc ggctgggtga
   389281 gacatgcagc acattcgcca ggcagtccgc atcgcgcaac ccgtcgtcgc gcgcgccggc
   389341 gttgaagagc agtacccccg gcccggcctt ttctgacagt tccttcagga tgtcgccttc
   389401 ggcgatcacg gcgatgaggc cgatgccttc cgccttcagc ccgtcgagcg ccgcccctgc
   389461 ctcttccggt gcaaccgcct gcgtcgtcac cgtgtaatcc atgcccgtga aggcaccggt
   389521 cgtccgattg tcctcattgc ccagcatggc gccggcaaag cccagatcgg cgggcggcgc
   389581 atcgagccgc gagatcggcg gaccgacgac gcgatcgatc ctgagcaccg ccgtcttcac
   389641 ctccgccgcc tgcgagggag aggtgacaag catggccacc cagaaaaggg cgagcagacc
   389701 cgataggtga gggcacttcc ccttttctct gaatcgcgga gttgctcgaa ccgtccgttt
   389761 ctcggcaatt ccggacggaa aaccgctgcg cacccttcct ggaattgctt caagcatgcc
   389821 ggaccgacct ccccctgaca ctccctcagg gacggagact aacagtgcaa ttcgtgtcgc
   389881 aaaaccgata cttaaggagc gtagtttagc ggtatgcgtg tgctaggctg aatttcatgc
   389941 ggcacatcct ggtagctttg atcctgacaa tgtggcctgc tctggcttgt gcagcgctgg
   390001 acaagccgct ggagcccggt gccaaggtgg cgttcctcgg catgaccttc atcgatctgt
   390061 cgacggaggg cacgtataac ggggtgcggg ctgacgagac cgcgcggctc gaactcatgg
   390121 aaagcgccgc gcgtgaccgc ttcgttcagg aaggtttcgt catgctctcg acggcgcccg
   390181 tggccgccga actcgccagc acggtaaacc cggccgactg caacggttgc gagctgcaca
   390241 tgggcgagcg gctcggcgcc gattatgtgc tcgtcggcga ggtgcggaag atctccaacc
   390301 ttatcctgtc ggtggaactc gttctgcgcg acgtgaactc cggcgagatc ctgcgcggca
   390361 ttgcggtaga catccggtcg aacaccgacg acagctggct gcgcggcatt cgctacattt
   390421 tgaagaacca tttcttcaaa tcatgaagcc cgatccggtg cgggagacat gcggcggcac
   390481 ctgcctcact ggccgccggg ctccggctcg atccgctccg tcggatatcc ggccgtcgcc
   390541 cagccgtcgg tgccctgcgg ataccagaag acatgggtgt aaccgtattc cagagcgcgc
   390601 ttcccggcat tccaggacat ccagcagccg tcgagacaga agaacagcac cggccgatcc
   390661 ttgtcgccgc cggtcgcctt ctccaggccg gcccggaaat agtcctgcat gacgtccgcc
   390721 agcatgccat agccgacatt cggcagccac agggacgacg gaatggacag gcgcggcttc
   390781 tcgttccaga ccgttccttc ggggaggttg gccggcttcg gcggccgcgg caggacatcg
   390841 atgaaggcca cctgaccggt cttccacaat gcatgggcgg cttcggtcga aaccacggtc
   390901 gcgcccgaga gcgtggcagg cacctcggcg cggtattcgc tctcgcgata gccggcaggt
   390961 tcctcggccg ctgccgccgg aaaggcggca aacagaagca ggaccagcga atggagccac
   391021 gggcggatca tttcggcgtc tcgagaggac cggttcccat gtcgttcagg agcggcacgc
   391081 cggcatcggc gagaatggcg tttatttcgg actgattgcg acgaatgagg gaattcaact
   391141 tgcgctccca gaccttttcg ccctggcgaa cgcccatggt aatgcggtag aaaagcctcg
   391201 gtggagtgga ctccgccagg agcggggtcg ccttcagctt tggatggctc gccttgacga
   391261 gggggccacc gatcgggccc cataggatcg ccgcatcgag agcgccggat tccaggtcct
   391321 tgagcatgtc gtcggccggg tcttcgtacc ggcggtcgac catcagatga taccccttcg
   391381 ccttgagcag cagtccgttt cttgccatat gggtcgccgg cggcgttccg gcgacgatgc
   391441 cgatgcgctt gtccttgaga agaggatcgg cgagcgtcgt cacaccggca agcggaccgc
   391501 cggacgcggc gatcagcaca taggccgagg tgtaatagtg attggtgttg agaaccatct
   391561 cgtcaccctg tgcaaatccg atgaccacat cgcaggcatt ggcctgcagg gtcttgcgga
   391621 cgaagccggt cgccatcgga aaccaggtgt actccagcgg cagtccgagc ttggatgcca
   391681 tcagttcggc gatcttgttt tcgtatcccg caccctcgcg atcggacata ggcagattgg
   391741 cgggatcggc acaaacccga aacgccgtct tcgacacaag gtccgatgtc tgagctgccg
   391801 cgggctggga gccggcgacc gctggcagca taatgccggc cgctgtcaag aggctactcg
   391861 tggccgaggc aagccttttc agcatccttg atcgcatcgg atttcgcttc cttcttggcc
   391921 ggacgtcctc gcggcaatgc atcggctccg cgcgctttca gatagacgta gatgtcgtcg
   391981 agataacaca tcacattgac gttctcgccg aaggcgggca tcaccgagtt ctcggcagcg
   392041 ctgaccttct tgcgtccgtt ggtgacgaca tcgacgaaat cataatagtc catgtttatt
   392101 gcagaggtct tcagggctgg tgcatagctc gatccctcgc cctccgggcc atgacagacg
   392161 tgacattccg agtggtaccg gcggaagcct gaataggtca gccagtccac cgtgccgtct
   392221 tcggtgacct tgaaagtagg aacgtcgtcg gcggtgtaat agcgcccgtt ttcgtcgcgc
   392281 gcagcggtga tattgtccgg cgcttcttct gcgcccgcgg cgcccgccat aagcgtgaac
   392341 agggcgagga tcatcggcac ggcgtgtctt gttctggtca tcttgcatcc tttggggctg
   392401 gtatgaatcg gcgcgggctt gagagcccgc gccgattccc gggctaagat tgccgcttat
   392461 tccggcagct tgaacacggt gagcgtaccg ccgagcgcgg tgtagttgct gagggccgag
   392521 tagccgccaa cggctccgag accttcagtt gggttggtca ggcccgctgc cagaccgatt
   392581 ccggcccagc ccccaacacc cgagaggacg gccacgtact gcttgccttc gcgggcatag
   392641 gtcatcacgt tgccaatcac tccggaaggc gtcttgaagc gatagagctc cttgccggtc
   392701 gcggcgtcga ccgccttcag ataaccttcg agcgttccgt agaagaccac gtcgccggct
   392761 gtcgccagag cgccggacca gaccgagaac ggctccggta gggaccactt gattttgcct
   392821 tccttgttgt cccaggcgat gaagttgccc atgccgccat ggctatcctt cggcgggtac
   392881 atcgacagcg tggcccctac atagggctgg ccggcggtgt agcttacccg gaagggttcg
   392941 tagtccatgc agacgtggtt ggtaggcacg tagaacagct cggttttcgg cgaataggcc
   393001 gccggctgct ggtccttggt accgagagcg gccgggcaga cgccggtcgt gttggtgtct
   393061 tcgccgttct gctcagtcga atactgagct acgacttgcg gccggccaaa ctgttccgac
   393121 ttggagtcca tgaccacttc agtcgcccag ttgacggtgg gatcgtattt ctccgctacg
   393181 agcaactcgc ccgtgacgcg atccatcgta tagccgaagc cgttgcggtc gaagtgggtc
   393241 agcagtttgc gatccttgcc gtcgatctgc tgttcggtca ggatcatctc gttgacgccg
   393301 tcatagtccc attcgtcgtg gggcgtcatc tggtagaccc atttggcctc cccggtatcg
   393361 acgtcccgcg cgaagaccgt catcgaccag cgattgtcgc caggccgctg ggtcgggttc
   393421 caggtggatg ggttgccggt tccgtaatac accatgttga gttcgggatc ataggagtac
   393481 cagccccagg tcgtaccgcc cccgatcttc cactgatcgc cctcccaggt cgtcagacct
   393541 gagtcctttc cgaccggctt gccaaggtgg gtcgtctttt caggattcat cagcgtgtcg
   393601 ctgtccggcc ccatggagta agcgcgccac aggagcttgc catccgcgat cgaataagcg
   393661 gtcacatggc cgcgaacgcc gaactcgccg ccggatatgc cgacgagaac cttgtccttg
   393721 acaggcatga cggtggcggt gttggtctcg cccttggtcg catcgccgtt cttgacgctc
   393781 catgccacct tgccggtctt ggcatcgagt gccacgaccg tcgtatcggc ctgatgcaga
   393841 aagatcttgt tatccgcata ggcgacgccg cgattgaccg tatcgcaaca catcaccggg
   393901 atcacgttcg gatcctgctt cggctcgtat ttccagacga tctggccgtc tttgctgaga
   393961 tccagcgcat agacggtgtt cgggaacggc gtatgcacat acatcatgtc gccgatcaca
   394021 agcggcgaac cttcgtgacc gcgcagaacg ccggtcgaga aggtccaggc gacctggagt
   394081 ttgcctacgt tgtccttgtt gatctggtca agcttggaat agcgcaggtt ggcatagtcg
   394141 ccggtctgga tcgcccattg gttggggtca tcgatgagct tctgcaaatc atcgttggcg
   394201 aatgcgacct gcgcaccgcc gcctatcgac atgaaggcaa gcatagtaag aagtcgtttc
   394261 atttcatcct cctcttgggt gctgccgata gggccgttca acccgctcgc cccgggaaaa
   394321 ccttacggtt ttcctcatct cccggtatcg gcttgcgact ctgccccgcc agccggaaaa
   394381 gctccggatg ctacggggga acattgctta tctcggtgtt tcggctcctc ctcgtcggtc
   394441 aggggaaagt tgccagatat gcgatgatgt cggcacgttc ctgatccttg cgcagtcccg
   394501 caaaggtcat cttggtgccg ggcaggaagc ccttcggact ggtcagaaac tcggcgatct
   394561 tttccggcgt ccaggtaagc ccggcctcag ccgctttctc gatcgccggg gaataggcgt
   394621 agccctcgac cttgcccgca gaccggccga tgatcccgtt cagcaagggg ccggttttcg
   394681 atttggcatc cgggccgacc gtatgacagg cctgacactt gcggaagact ttcgcgcccg
   394741 ccgctggatc tccggctgcg ggatccagtg caagtgccgg cgcggctgcg ccgagaattc
   394801 cgccaatcag gacggcagcg gtcagtacgg aaccaagtct tgaagccatt ctttcctctc
   394861 ccttacgcgg cgttcagccg ctctgcatgc cagcgcacat ggtcttcgcc aaagctcgcc
   394921 acgaaatagt aactgtggtc atatcccgcc tgcagccgta cgacgccggc ttgccgacgc
   394981 tccgccagca accgggccat cgcctcgggc tgcagctcgg tgagaaactg gtccgccgcg
   395041 ccctggtcga tgaggatatc gccgtgccag ccgagttcgc tgagcagcag gcaggcgtca
   395101 tagctgcccc aatcggcctc gtcgtcgccg agataggcgg aaaactgctt gcgcccccaa
   395161 tcggaccggg tcggattgac gatcggcgca aaggccgaga cggatcggaa cagtttcgga
   395221 ttgcgaaagg cgatggtgag ggcaccatgg ccgcccatcg agtgcccggt aatgccgttg
   395281 acgccgttga ccggcagctg cgcctgcaac agggccggca attcggtgac gatgtaatca
   395341 tacatgcgat agtgcggcga ccagggcttc tgcgtcgcat taacgtaaaa gccggcgccc
   395401 tgtccaagat cgtaggcctc gtcatcggcc actccgtcgc cgcgcggcga ggtgtcgggg
   395461 aaaatcagcg ccagcccctg ctcggccgcg tgccgctgca ggcccgcctt gatcattgca
   395521 ttctcatggg tgcatgtcag cccggagagg taccacagga gcggcacgga gcgcttccgg
   395581 gcctgaggcg gcaaatacag gccgaatgtc atctcgacgc cgcaaacctc ggaggcgtgg
   395641 cggtagaccg actgggtccc cccgaaacat tggctttgcg ttacaagttc catcttcgcg
   395701 ctcaatagag gaccacgctt cgaatgctct cgccggaatg catgagttcg aaccccttgt
   395761 tgatgtcctc gagcggcatg gtgtgggtaa tcatcggatc gatctcgatc ttgccctcca
   395821 tgtaccagtc gacgatcttc gggacgtcgg tgcgcccgcg cgcgccgcca aaggcggtgc
   395881 ccatccaggt gcggccggtg acgagctgga acggcctggt cgagatctcc tgaccggccc
   395941 cggcaacgcc gatgatcacc gacttgcccc agccgcgatg cgaggcttcc agcgcctggc
   396001 gcatgaccct ggtgttgccg gtgcagtcga aggtgtagtc ggcgccgccg atctgatcgg
   396061 caccgcgctt cgtcagattg acgagatagg gcacgatgtc ctcgcccact tccttcggat
   396121 tgacgaagtg ggtcatgccg aacttttcgc cccagggctt cttgtcgttg ttcaggtcga
   396181 cgccgatgat catgtcggcg ccggccaggc gaagcccctg gatgacgttg agcccgatgc
   396241 cgccgaggcc gaagacgatg gcggtggcgc cgatctccac ccgtgcggtg ttgatcaccg
   396301 cgccgatgcc ggtggtgacg ccgcagccga tatagcagat cttgtcgaag ggggcgtccg
   396361 gattgacctt ggcgacggcg atctccggca gcacggtgaa gttcgaaaag gtcgagcagc
   396421 ccatataatg gtggatcttg tcgccaccga tcgagaagcg cgaggtgccg tccggcatca
   396481 gcccctggcc ctgggtggcg cggatggcgg tgcacagatt ggtcttgcgc gacaggcagg
   396541 aggggcagga gcggcattcc ggcgtataga gcgggatgac gtggtcgccc ttcctgacgc
   396601 tggtgacgcc cgggccgaca tcgacgacga tgccggcgcc ctcatggccg aggatcgccg
   396661 ggaacagccc ttccggatcc gcccccgaaa gcgtgaagtc gtcggtatgg cagatgccgg
   396721 tcgccttcac ctcgaccaga acctcgccgg cccgcggccc ttcgagctcg acttcagtca
   396781 cgacaagggg ttttccggcc tcgacggcca gagcagcgcg agtgcgcatg gatgcctccg
   396841 gtactacgtt atgtaagcgg cccttgtgag gccttgtaca cagattacag acgggccaaa
   396901 gcacaaagac aattgcgacc ttagtgtgta aaacgcgacc tttggcttcc ccctcggtcc
   396961 ccctatactg aaacccgtga gaacacggag acatcaagga tgagagtcgc ctgtcatgcg
   397021 tttggtccaa tgcgccgcct ggcgtttggt ttgacggtcg gtctggcgct tggcctgaca
   397081 caagcccccg gcaattcagt tgccatggac ttttccgatc cggactggcc ctgcatccag
   397141 cgcaaggtcg agaaactatc cgcgagcctg atgtggccag cgcctgtcac caccgctccg
   397201 ctctcagccg aggcaaccga gctcgtcgaa atgctatcgc ttcggcgggt cagcctggaa
   397261 gaggccgatg cgcatgtccg cgcctttgtg gagcgggcca aggtcgacgg caatgtgctc
   397321 ggcaatgttt tttacggcgt gttcgaaaat atcgccgaga cccgacagcg actgatcacg
   397381 gggataggtc gctactcccg gagccagatc gcactctcat cccgaatcga cagtgcccgc
   397441 gtcgaaatgg cgaagctttc gaaagtggaa agtcccgatt tcgaccgcat agacaagctg
   397501 gaggagcaga tcgactggga cgagcgcatc tatcgcgatc gctcgcaggc gcttacatat
   397561 gtgtgcgaaa cgccggtgct tctggaaaag cgcgcctatg ccattgcaca gatcctgctc
   397621 aagcatatgc cggattgacg tttgagcgca ttggaagtgt acattgtacc ccccacaaac
   397681 gattgcgcgt ttctgacgcc gcgctaagga tcccactcca tttccgtata ggcggccgtg
   397741 gcgttttgcg gattcaagag atcgaacagg ctccatcggg ctgattcgct ttggccgacg
   397801 gtctcgctcg cgtctcccag cgccaggccg tcgtcgagcg ctttcttcgt gtcggattcc
   397861 agaacacgca gatagcgttc gagcggctcg gctgcctgcg gccagtcgag cagcgggcct
   397921 ccatgcccag gcacgacttt ccgcgcgccg agtcccttca tttcggaaag gactgccagc
   397981 cagccgcgca acgatccgtc gagggccggc atgtgcgtgt cgaacagcag atcgccggcg
   398041 aaaaggatac cggaagtcgg gtcgtagatc gtgaggtcgg tagaggtgtg cgccgttggc
   398101 caggtgcgca actccagcac cctgccgccg aggtcgatcg cctcctgctg cgctgccgtc
   398161 cgatccggtg cgattatacg gctacccagg aacgcggtct cgccgagccg ccgggcatag
   398221 cttgcccgat agtcctcgac gcggtcggcc agcgcacgcg gcaaatcggc ctggccgagc
   398281 accaccgcgc cggcctcgcg gagtgcctcg gcgccgaaga catggtccgg atgcatatgc
   398341 gtcaggatca gattactgat cggcaggcgg cttcgttccc ggattgccag atagatctct
   398401 tcgcccaatt tgcgcgcccc gccggagtcg atcacggcaa tgctgcgcga ccccacgacg
   398461 aaaccgaaat tggaaacgtc gccgccgttt tccgcatccg gctccgccac ccggccccga
   398521 tgcaggaaaa cccccggggc ggcctcgctg aaggagagaa ccgacttggg cctcggggca
   398581 cagaatggcg ccttctcggc ccaattgccc ggccggcgcg tgacggagtg cagcgcctgc
   398641 tcgcaccccg ccttcgtctc cgccccaaag ccgggcagca gtgccacgcg gcaggtctcg
   398701 cgcggcggcg cgtcgggaac ggccgcagcc agaatgcaca tggtcacgaa tgcttcgaac
   398761 acctgaggcc cctgcgtttt tcacaaagtg ggcgatttac aagcttgcgg cggccggtcg
   398821 cgccagacaa catatccgaa aggctcgctt ctgttccctg gcatttctat gctaaaggat
   398881 acatgcagcc tttccaaaaa gggggctttg aaccatgaag ctcattctcg cgcttattcc
   398941 cgtcatgctg acggcaaatc tcgcacttgc cgagccggag aagccggaca acccgcttgc
   399001 agacggtacg acctggcatg acttgaaagg cgacatcgtc ggagaggcgg ccatcctcga
   399061 cggcacggcc ctgttctccg tcgcggcgcc ctaccgtgcc aacgacgccg cgacggtgcc
   399121 catcacgatc gagcagacgg acgcggcggc ggggccgatc aaatcgctca agctggtgat
   399181 cgacgagaat ccggcgccgg ttgcggcgga aattcgcttc ggcccgacga tggcaccgct
   399241 gaaattcgaa acccgcgtgc gcgtcaacca gtactccaac atccgtgcga tcgccgaaac
   399301 gccacagggc attttcatga atggccgctt cgtcaaggca tccggcggct gctcggcgcc
   399361 cgctacgaag gatccggtcg cggctctgaa gggcatggga gagatgcggc tgaagctctt
   399421 cggcggcgag ggtaaagtac aaaaaccccg ccgcgaggcg cagatcatga tccggcatcc
   399481 gaactattcc ggtctccagc gggaccagat cactcaactc ttcgtcggtg ccaagttcat
   399541 ctccgaactg gtggtgaagc agggagatga gcttttgttc gcgctcgacg gcgggatatc
   399601 gatcagtgaa aatcctgtgt tccgcttcag ctataccgac aatggggccc cggacttcac
   399661 ggtccatgcg gtcgatacgg acggcaatgt cttcgaccgc gtcctgccga agacgccacc
   399721 cgcctgacgg gtggccacat cagaccgcta agtgcccggc cttttcttgt cgcaatttcg
   399781 gacggaaaaa accgctacgc acttttcctg gaattgcttt tagaagcaca gcatctccgc
   399841 ctctgcctgg gcgcgcctca gatccgcgac catggtgcgc ggcaccacgg ccgacttgaa
   399901 catggcaagc tgttcgccgc ttccctgctg gagagacagg accgtttcgg cctgaacata
   399961 tttgtcatag ggcaggatcg aggcgatcac atcgatcgag catgcgcatt tgctcaagac
   400021 ttcccggctc tgcccgttgg cggccatgca gccgaacaca taatcggccc ggacctcagt
   400081 gggataatcg ttcagacgct ccgacatgct ctgcccgcct gcagggactg ccgtcaacgc
   400141 aattgcaagc gccgacaagg cggcgcgcat catggctgat cctcccctga cgcattcgac
   400201 cctgacgctc tcaaggtaat tgcgtgggaa tagccggccc ccgagctgtc ggcggccgaa
   400261 ggaatagtgg ccaccagcga aaagtaccag ccgggaacat cttccgaaac ggtaacggcg
   400321 agcgacagat cggcaacccg ccccattttt tcgcgcgcct tgtcgtgttc gaacggccgg
   400381 atcgtcacct cacgcgccgc gatctcgcgg tcattatagc gcagcgttac cggctcgatt
   400441 tgcgcatccc gcagcaaagc ctccttgatg cgattgcgca tatagaaggg gctgccgccc
   400501 gactgtgccg ccagatcgga aagcacgctt tcgagaaaat acatgatcag cggattgccg
   400561 accgaacgcg gataattgcc gagcccccga gactggctcc cctgatagag ggtcatcgaa
   400621 acattgtcgc cggcctgcac cttcaggccg actgcgaagc gaccgctcct ctcacctgaa
   400681 tcgaccccgg acacgacctt gtcgtagacg aggccaccct ggggatctcc gttcccggcc
   400741 ttttccgcct ccagcccctt cagcgccgcg gaatggaaga gaagctcgta ggtctctgca
   400801 gcggctgcgg atccgtgggc tggtccaagc aagattagag cgatcaggaa aaaaatgcgc
   400861 atcgcggatc taccgtctga tatgaagctg ccgttcaacg acaccgagcc tagcagtggc
   400921 tccggcaatg tcatcggaga cctttgtctg tgtttgcctc acgccacgcg ggcccgggtc
   400981 ttccagtcga tcaacgctct gagccgcacc agttgcacag gcttggtgag cacggcgaag
   401041 gacatttcgg tacagagctg caggaattgc cgctgccggt tggcggaaat gatgatagcg
   401101 gggatttccg ctccagcgag cgcccgcagc gtgcggatgg tctctatgcc gttatcgtca
   401161 tcgttcaact gatagtcgac gagcagaatg tcgggcgccg tgccgatttc ctgcatcagc
   401221 gctgccgcat cggcagtcga gccggccgcc agaacgcttg ctccccagct ctccagaacc
   401281 tgcgtcattg cgtgtagctc gtcggcgtcg ttctcgacga tcatgacgat caggtcgaga
   401341 ctgccctcaa gcatcggctc cattctcggc tcctcgctca cgctggcacg gcccggcggc
   401401 gccagcggca cttcgatcga gaagacggaa cctcggccgg gctgcgatgc caggcctatg
   401461 gggtgaccga ggtgccggca tgcccgctcg acgatcgaca ggccaagtcc catgcccgga
   401521 cctttcgcag cgccactggc tcgggtgaat tccttgaata tccgcgcccg gtcctcctct
   401581 gatattccga cacccgtatc ccacacttct attcgcacgg catcgccttt cagccggcaa
   401641 ccgaccagca cacgcccgcg ctccgtatat tggatggcgt tgacgaccag gttctgaacg
   401701 caacgcatca ggtagcgctg gtcgctgctg acccagcgcg tcgacggcac gattcgaagc
   401761 tcgatcgccc tttccgtcgc caggggcgcc agatcctcgg ccacaccctg cagcaggctt
   401821 ccgagattga acgaagtgac gttgaactcg gcgcccgaac tgtccagacg ggaaatgtcg
   401881 agaagcgcct gcagaagcga ttcgatggat gtgaaggaac gcttcaaacg gctgacgacc
   401941 tcctcgacac ccggctgccc catcctgtcg gtcagcatcg acagataaag cttagccgca
   402001 ttgatcggct gaaggaggtc gtgactggcc gccgccagaa aacgcgtctt ggatgtgtgg
   402061 gctgcttccg cagcttcctt ggcgtgtcga agggcggcct cgatttttgt ctgttcgtcg
   402121 gcgtggattt gcagcaggcg attggcctcg gtcagttcgg cggtacgctc ctgtacgcgt
   402181 tgctccagaa gtgcggaagc ttcggtctct gccgttacgt ccattataga aacgatgaag
   402241 ccgtcgtcgg gcagggaatg gatgcggata tcgaggccca tcccgtcgcg ccggcggaag
   402301 cgctcctgaa cggcctcgcc acggcgcacc gccttgaacc agccggatac cctggagcga
   402361 cgcccctcgc gatcgagaat ttcgtggcgc tcgacgtgtt cgacaatgcg ctggaaagga
   402421 cttcgcttct ttagaagcga gagcggtacg ccgagaagct caccgaagcg ctcgttccga
   402481 accagcagtt cgcctctcga ggaaaacgtg cagatgccga gggacatatg gtcgaaggcc
   402541 gcctgcagga gatgagactg ctggtcgatc agacggttct tctcgcgccg gttctcccgt
   402601 acgatgtccg tgatttcggt ctgcaggacc gtgatgttgc cggaactggt ctgccgatag
   402661 gaaatctgga accagcggtc gttccgcaga accatgacga aggatgagaa gcgctgccct
   402721 gacccctgct ccttcgcgac cgggtgcggc cgcccggaca ctccgttttc gtcgcggttc
   402781 agatacttgc tcgcattgac tgctgccagg tagtcgtcga agccaagacc tggcttgatc
   402841 agcggctcga catcgggcag caattgccgg aactgggcat tgcaggcctg cagccgctct
   402901 tcggagaaga gagcgaagcc gtcctccatc gccaccatgg catcggcgag attcctctgt
   402961 atgcgctcct gcgtctggta ggccacctcg agctcactcg aagcccggtc cagcgtatcg
   403021 agcgcctttt cgagatcctt ggtcttctcc cagacctccg cctggagcgc gatagcggat
   403081 tcaaagagag aataggcagt gccgccgact tcgtgcccgc gctctgcccg gttgacgagg
   403141 gcttcgatga tcttggcctg cttggcaatc tggatctcat aggcctcgtt cggatcgatc
   403201 atagcggcgc gccctccttt ggccggaaaa acgcgacgcc gacgaaggtc tgattcacgt
   403261 ggacgccgag atgctgctcg ccataggtgt tgaagccgac gacgcggttc tgccgcaatt
   403321 gctgggaaac ctcgctgtcc aggcccttcc gctcgatctc gagcttgcgc agatagcaat
   403381 cgaatcccag tatgaagtcg ggcgcttcgc cgtcatggcc gttgaccgcc agccccgtct
   403441 cgagcgtgcg gatgatctcc ttgccgcgac ccagccgcag caggagacca tcgtctatcg
   403501 ccgataggaa ggtgaggcca tgctcgccgt gtatctgctg tatggcccgt acgtgataga
   403561 gattgccgtt gcgcaccagc accgggttct ccgcaaagac catcggtgac aactcgtcga
   403621 ccggtacctt gacgagccgg gcatattcct ccgccgccgg agagccgttg atttccagaa
   403681 ccagccgttc ctccggaacg gcgcgggtca ccaccatgcg cttgtcggtc ggctggaagt
   403741 ggtcgaagcc gaggccgctg aactccaggt cggtttcgag cagcaggaga agcgccgcat
   403801 tgctgtgaaa ttcaccgttg cggagtacct gtgtgcgctg gaaccgcagc ccgtcgccgg
   403861 ccgaaccgcc gaaaaccggg atatccttca gccccgcctc gagcgctgcc accagaacat
   403921 cctcctgctt ggacagtccg tcggcaaaga tcagcgccaa ccgctttcgg cccggcgtaa
   403981 cgcggaactg cgaggcgagc cgctccgtct gcgacacgac atcggcaatc gaaaccggag
   404041 aaatcggctg gaacaggatc gaggctaccc gaaaatgatg ccgttggaag gcaaccgcca
   404101 gcagggcgtc gttttcatag ccacgaggcg taatctggcc cgccgtcgtg cagccgaaga
   404161 cgaccgtgtt cggcaacgac tttctaagcg ccgcggcgag gtcgtccgtt tgcagcctgt
   404221 tcggcacgaa cagaaaaatg aaacttggcc ttgccgtggc gagctgccgc ctgatgtcgg
   404281 caagggcagt gaacgcatcc tcggcgcgtg atgtcgcaag ccgcaccgcc tccgccggtt
   404341 tgcgctcaag atcatcgaca gccgtcatgc atggtcaccc tcctactccg atcccgccat
   404401 ccggatacac ttcattgaag gctgtggcgg atcgatactt cgcggaccag catggccgcc
   404461 tgggtgcggt tatggacacc cagccggcgc agaagcgccg tgatatgcgc cttgacggtc
   404521 gcctcggcaa gttgcatctc ataggcgatc agcttgttcg gcatgccttc gcagatcaga
   404581 ctcagtatgc gggtctgctg ctgcgacaga tgggcgatct tgcgtgagat cgtctcggcc
   404641 gactggtccg cggcagtcgc gcgcgcctga accgcatagc ccggcggcac ataggtcttg
   404701 ccgttccaga tatcctgcat cgcctcctga aaattatggc gatcgatgtc cttgggaata
   404761 aagcccgcgg caccggcggc catgaccgat tgaacgacgt cgtgcgacgt gaaggcggag
   404821 atcacaatga ccggtatatc gggcatcttc tccttgatct tcagaaagcc gctcaggccc
   404881 gaagcgtcgg gcaggttgag atcgagcatg atcagatcgg gcgagaagcg caaccgcaac
   404941 tgctgcagcg cttcactcag cgacgtcgcc gttctgatcc ggcgtgtatt gaaggtgctt
   405001 tccatcgtcg cggccagcgc atcgcaatag agcggatgat catcgatcac cagggccgac
   405061 tttatcgaaa gcgaatgaac gggcaaggct gtccgtggca tggttctcct cccgagacac
   405121 tgcaagccga tggagcagca tcgagccgct ccagatgcac cggaaacatc tgttctccca
   405181 aggcatctct cccaaggcat cgtactctcc ccagcacgat gcgaatcgtt gttgcacagt
   405241 tttccacacc gggcaattcc gagttttgac gatgcgacac ccgatcgtcg ccgctgcgct
   405301 ccagagcctc aaagtctgat gctggcgggg ggccggacac tcagaccggc tgggtcccat
   405361 ccgcaagccg gcagcgccat ttcttgacgc gaagggcggg gtgctgctcg gaccattcgg
   405421 cgatatacac cgcagactga aacatgcatt gattcaagga tctcaagtcc tgaaatcgta
   405481 gcgtttcctc ccggcacttt tcgggtgccg atgcgaggca tacggtcagt acgagcgtta
   405541 ccgggtccat gacttttccc gtttcggatg aagcttacgc atgggctaat ataacctcca
   405601 acgcgcgatg gcgccagccg ccggcagccg ccttacatca ccgccacctc cgagacggtt
   405661 ctcgaggaag gcatgatctt ctcgatcgag ccggggatcc ctcccgggcc gcttcggaat
   405721 ccgtcttgac gacatcgtgg ttcttcggcg cgacggcccg aagttttctc ttcgctgccc
   405781 cggacagttc acctcgccga cggctgacgg tctcgttcaa cgcgtgttgt cgagaggccc
   405841 ggcccgcatc cgcggcgccg gcctctttat taaatcggat gacgggcatt ccctatcggc
   405901 ctgcattggc cgcctctttg aaatgttcgc gaaacaggtt cttgaagtcg cggaacttcc
   405961 cgaacccgag atgacttgcg agacgcacaa ccgtcgttct ggacacgccg cacttgcccg
   406021 ctatggatgt tgccgtgctg aaggcgatga actcgggttg atcgagaaca gcgcgcatga
   406081 cacgctcgag ctcccccggg aatacgactt ccctcttggc gatcatcgac ttgagctcat
   406141 acagatttga cggaggagtt cggctttccc gccgggcctg cgccttgcta ccgccaccgt
   406201 ccttcgtgcc ggatgcgtgg cgcggcggct gcgtcgtcat cggacaccct cgatcaggcg
   406261 gatccagtcc gctgcacggg cggcggcctc gatcagaaca ggttttggcg ccttgtacca
   406321 ctctgcgcgc gaaaggcggc ggtgttcgcg gatatgcgcg atcgccgcat ccagggtcgt
   406381 gaactgcgat gggagcgtca ggtgcaggaa cagtgccatg acgatgaccg agcgagagcg
   406441 ccctccccga cagttcacga gtacgttgcc ccgctcccgc ctcggatagg agggcttctc
   406501 cggcaatacc tgctccagcg ccgcacgcag gatgaaatag gccgcgacca tctgcgtgtc
   406561 cgggttgccg gaaccgtcga tcaagccgat cttgtagtaa cggatttcgc ccggtccata
   406621 ggcgctgccc tcgtgatcgg atacgaggcc ggcccgtcgc acatagttga agtccaggtt
   406681 taccgcacag ttgaccacgg tggtgacgcc attctggcgc aggagctcca gatcgctggc
   406741 accttccttg ccgctgatga agagatcgac ttgatagagc ggatgcttct cataaatcag
   406801 gctgagcttc gggagttcgg cggcgatcga ttgcgggtct gggtccaact gctgcatgtt
   406861 tttactccgg cgcagacctc aggtctcgcg ctgtgtccga ttgggaacgc ttgctactgc
   406921 ccggtctttg caatccggga cgtcgagatc gatcgggcga cccgctcgag cgttggataa
   406981 tccgcccccc gtcctgtagc gatatagccc ggacacatga aatccggccc atcggccgcg
   407041 actttgccga gggtaagtgg ttcgtaccgc ccgccggcat tcttcaggat cagcgttgcg
   407101 gcggcaacgt cccaggcatt gaccccgaaa ccggccgcgg cgtccgccca tccggccgcg
   407161 acatgggcga tgctgagggc cgcactgccg ggccggcgca gcgtcgagaa ggtctccacc
   407221 aatatcccga aattggccag cgctgcctcc cggccatcga cacgaaaatc gcgcgccacc
   407281 ggatagccgg taatgagagt ggcgtgcttt tcgttatcgg cggcacgcga cgcaagcgca
   407341 ttgccgttca gttccgcact ttcgaggtcc gccgagaaca ttaggtccgc caccggatcg
   407401 tagacggcgc cggcaagcac ggctccctcc ctcacgaccg cgactgatac gcaccagaag
   407461 gcaattccgc gcgcgaagtt cgccgttccg tctatcggat cgacatacca ctgaaactcg
   407521 ccgtcaccgg tctggccgcc ctcctcgccc atgatcgccg agtttggttc atgctcgagg
   407581 atgtaggctc gaatgatcgc ctccgcccgc ctgtcgtgga cggtgacgat atcgtgcagg
   407641 tccgccttgt agtccacggc catttcggac cggaacgctt cgagaagagg catgcgaacc
   407701 gcaagggcgg ccccccgcgc aatttccgca agtcgccctg agagggcggc ggaatcggga
   407761 tcggcgatat gcgatccgga agacggcttc ggctgcattg aatatccagt ctgttgaaat
   407821 cggtctgtcg gagaaaggcc ggcgcggggc cccgcgccgg cctgaatcat ttgctgtaat
   407881 tggtgcgcca gaggtcctgc cactcctcac gacggtcgaa gtcgctgaga cccgtcgcag
   407941 cgtcgtagcc gaagagccgg tcggaaacgg ccatcaaccc ggatggttcg tccgcgggca
   408001 tcctgatgtc ggtattggtc ggcaacttgc cgtccttcat ctgcggcgcg atgccttcct
   408061 cggtcaggat atagtggatg aacagcttgg cggcgttcgg gcttgaagtc ttcgacgcga
   408121 tcaggcccag cttgacatag gtccagccga cccagggctc gagctccttg cagatgccga
   408181 gcttatagcc tttggcttcg ttgtcgcgga atttggccga actcaggaga ccgaagaacg
   408241 gctccttctg gcccggcgcg ccgacggcct cggccactgg atcgtcgccg tccgtcgcga
   408301 gcggcgcgtt ctgcgccatg gccttgaccc aggcggcgga cgcgctcttc tcctccgacc
   408361 gcaattcctg gccgaaatgc gccttgtagg cggcggcaac cttgtcatcg ccatgtgcct
   408421 ccatctggtt aaaccagtcg gtgtaagtgc tcttcgtcag cggatcgacg agcgcgacct
   408481 tgcccctcca ctgcggctcg gtcagctccc agatgttgga gaccggacac ttgtcatagg
   408541 cttcggtatt ataggcccag acgttggcat tggttgaaat cgccagcggc ttctggaact
   408601 ccggcggtat ttttgcggcc atatcctccg gcagatagct ctcgacgaac tcgtccggca
   408661 gaagctgcgc aagcgccgcc ggcgcatcgg taatcaggac cacgtcgccc tgcacattgt
   408721 tcgcctgcgc ctcccggatg atcatttcca gctggctgtt cgccgacacc ttcatgccgg
   408781 tcgctttcag cccgtattta gcgttgaaat tctctgccat ctcgacgatc ttgccggtgc
   408841 tgtcatagat ggtgatcggt ttctcgttct ttgccgcctc gatcagacgg ttcagatcaa
   408901 acccgcccgc cgcaacagct tttgccccga ttagcccggc catcaaaccg accgtggcga
   408961 tggtcgccgg gcccactttg ctgttcctcg acatcttcgc ttccctccca aggagcgcga
   409021 cggcaaaact gccatcgcct catttccgat cggccgtctc cgaaatccgg ccggccctac
   409081 ttctggtagt tcacgcgcca gaaatcctgc cacgtctcgc gcgcgtccca atcgtcgagg
   409141 ctcgttgcca tgctataggg cagaagctgg tcgagaaccg ccgcgatccc ggaaggctca
   409201 tcctcaggca gagcgacctc cctgttggtc gacatcttgc cgtcgaccgc ctggggagcg
   409261 atcccttccg cagtcatgac atagtggatg aagaggcgag cggcgttcgg gctgtccgtg
   409321 cccttggtga tcagcccgac ccccggatag agccagccga cccacggctt gaggtccttg
   409381 cacagaccga gcttcatgcc cttttccgca ttatcgcgaa acttcgcgga gctcatcagg
   409441 cccatgaagg gctccgattg gccgggcgcg ccgaccgcat cggcggcggc cgcatcggca
   409501 tcggtcagga gcggcgcatt cgcggcaagc gccttgaccc aggccgctgt cgcgctggtc
   409561 tcctcggtct gtagctcttt gccgtagagg tccttgtagg cggcagcgag tttttcgtct
   409621 ccgtgcttcg ccatctggtt gaaccaatcg acataggatg ccttgccgag cgggtcctgc
   409681 atcgcaacct tgcccttcca cttgggctcg gtcagctgcc agatattcgt gaccgggcat
   409741 ttgtcgaaga gttcggtgtt gtacgcccag acattggcgc tggtgacgac cgtcagggga
   409801 tcctggtgtt ccgccgctat gttgccggcg aaatccgggg gcacccagct ctcggcgaac
   409861 ccctgcggga tgagctgcgc cattgcggcg ggagcatcgc tgatgatgga gacgtcgccc
   409921 tgaatgttgt tggcccgcgc ctcgcggatg atcatctcga gctgagccga tgccttgact
   409981 ttcgagccct ccgcgccgac gtcgtatttg tcggcgaagt tcttcgccat ctcgacgatc
   410041 ttgccggtgc tgtcgtagac ggtgatcggc ttttccttgc gggccgcctc aacgagcgca
   410101 tccatatcga aaggctcctc ggcccaagcc ccggagccaa gcacgcacag catcgcagtc
   410161 cccagaaaaa ggtatctgcc gcttctcgca ttccgtttca ttttgttcct ccctcagcag
   410221 gttgcttctc gtcgttcgtc ctatccggtc gtcagttgta ggttgcggtg ctcctcagcc
   410281 ggtcgtccgc ctctgcgatc cggcggccgt cggcatcgaa cacatgcagg gcctcgggcg
   410341 gcgcaaagaa gaggaccctg gcgccctgct cgaccctcgg cgggacatgc gtcgtcagga
   410401 acagggtgtg gttgtcggtc cttagctcca ggatccagtt gcctcccgtc ggcaggacgc
   410461 cggtaaccgt cgtctcgccc gagaagctcc cctccggcac gtcctcggtc cgcgcggcat
   410521 aacctatcgc ctcggggcgg ataccgacgg agccgatgct cctcagccct ggaagatgcg
   410581 cggcaagata ggcctcagcc ttatccgtca catcggatgt gccgggatcg ccgaagtcga
   410641 gaatattgat gggcgggctg ccgacgaact cggcgacgaa gcgattcgcc gggcgatcat
   410701 agatgtcgtt tggcgtgcct atctgctgca gcgtgccttc gttcatgacg gcgatggtcg
   410761 tcgcgagcgt catcgcctcc cattggtcat gggtgacaaa gacgatggtc gtcttgaatt
   410821 ccttgtgcag ccgcttgagc tccgcgcgca tttccagccg cagccgcgcg tcgaggttgg
   410881 aaagcggctc gtcgagcaac agcacgccgg ggttgattgc cagcatgcgg gccagcgcca
   410941 cccgctgctg ctgaccgccg gacagttgcg acggataacg atcgcggtac ttggcgatat
   411001 cgagcgcctg catgacgcgc tcgacgcgct cttccctttc cgctttgggc agcttgcgca
   411061 gcctcaggcc gaaatccgta ttgcgctcga tcgtcaggtg cggccacagg gcatagctct
   411121 ggaagacgag gcccatctcc cgtttctcgg gcggcacgaa cacgccgccg gagacgcagt
   411181 cgacgaccct gtcaccgacg cggatttcgc cgcccgagag attttcgagg ccggcaatca
   411241 ttctgagcgt cgtggttttt ccgcagcccg agggaccgag caggcacatg aattcgccat
   411301 cgcggatttc cagatcgaga tcggaaacgg cattcgccga attcacgccg tagtttttct
   411361 gcgcaccgcg caggttgatc gtgggcatca gcttccaagt ccttctgcaa gatttgtgcg
   411421 ggtcagcttc tgggcgatga gcgtgcccag ataagcgatg gcggcaatga tgagcaccac
   411481 ggcgttagcg gcctgcgtgt agtggtagtc gacgaggcgc aatgaatagg tggtcagcac
   411541 atccgtgctc ggcacggcga ggatgacgaa gaggctaagg cccttgatcc cggagatgaa
   411601 cggcagcagc acgccggtga cgagcgagcc cttctggatc ggaatgacga tcgaagtcat
   411661 ccgtctgagc cagccggcac cggcaatctg ggccgcctcc tccgggtcct ttccgagctg
   411721 agtcatcgca gagatgccgg cgcgcgaggc gtagggcatc tggtctgcga tgagcgcgag
   411781 cacgaggatg acgaccgtgc catagagtgc cggcatcggt ccgcggggta ctgcgaacag
   411841 tgacagatag gccgcggcaa aggctatgcc aggcaccaga tagggcagga aggtcacctg
   411901 ccggagatag accgacagca ggcgaacagg cgtgcgaatg accacatagc cgaccagcag
   411961 gccgagaatg cccgacgtca ccgaagcgag ccccacgatc gtcagcgtgt tctttgcagc
   412021 tgcccaaagg tcgggactaa ggaggatgcc ggtcttcagc gcaacggtat cgagatcacg
   412081 accaatccaa taatcaaggg tgaagttgtc gagcgtgaat cgcgcgggca gcttcatgat
   412141 cgtcgacagg aacagggtga gaagcggcaa gcccacactc atcaggaaga ccgtggcagc
   412201 gaagcccgcc gccggcagac gcatgcggcc gaggcggctc tgccggtcca tcgagccctt
   412261 cgagccgatc gtgacgaagc gacgcgcctc gcgcaccagc cgtgcatcga tcagcagcgt
   412321 gatgatgccg atcagcatga tggagccggc gatcactccg gcgacccccg tctggcgcga
   412381 ggcgatactg cggaaaagcg aagtcgagag aacttcgaat ttgaccggca ggccgagcac
   412441 gtagggcacg ccgaactcgc ccaggcactt ggcgaagatg agcaccatcg atgaaagcaa
   412501 tgccggacgc atcaagggca ggatgatctg caaggccacc tggtgatgcc tggcgccgag
   412561 gatgcgcgcc gaatcctcga gctgcgagtc gaagcgcctg agcgccgaac cgaaaaggag
   412621 gatgacaaag ggtgtgtagt gcagcgccag gatgatggtg attggaaatc gcccataagc
   412681 gagccagtcg ggcggtgtca gcccaaccgc ctccagccaa cccggctgac cgccgaccgt
   412741 gcggttcttg aagagcgtgg tccaggcgag cgcaaaggtc caggccggca acatgtaggg
   412801 tacgatcagc gcggtcgcga accagcggcg cccgaacata tccgtccggc tgatgagcca
   412861 ggcgagcacg gtgccgatca cgagggacag caaaatggcg cccatcgcca ccgagagcgt
   412921 attgagaagc gggcgccaga acaggtctgc cgacaccgga gaaaacagca ccctgtcgag
   412981 gtagtagagc gtgaactcgc cgacatcctt gctcaggcgc cgctcgtgcc cgaactggac
   413041 ccgggccgca tcgagcacga tggaaatgat cggtacgacg atcagatagg tgaacagcag
   413101 tgcagtcagc acgcctatga gtgtcgtggg ttcccgtaac gcaaccttca gccgatagcg
   413161 ccaggcctgc caggccgttg gcgcggcagg cccgtttgcg gccgctaccg ccttcgccga
   413221 ttcacttaga agagccatca ttcctcccat ggccgctaat gcatatttcg ccagagcctg
   413281 atgtccgccg acgccggttg aacgcgcttc gcggagatgc aagcctcttg cgcggcgacg
   413341 acggcccacc gttcctcccg gagccatgcc gctgttccga cctttgccgg ccgccgacgg
   413401 aataaaaatt ccataattgc cgtcgttatg gaacgtatga tcgattcagt ccgcccgttt
   413461 gtcaactgaa aaatgcacac gtgatcattt gattatctcg ttgttttcat taatctattt
   413521 tcctgcgaac acgtgttcag ttttattccg gttcgatgca ggcgggatga agctgtcggg
   413581 catcggggaa gacggcccga aatgagacct gccgccacgg cccgcgtaat tttccgattg
   413641 gaactttgcg cagtttgtgg cctctgatag agggctgatc gatgccgaaa ggaggacgga
   413701 tggcgaggac ttttgtgact gccgaagagg tcgcaaagcg tgcgggcgtg tcgcgctcgg
   413761 cggtatcgcg caccttcacc cccggcgcca gcgtctcgaa ggcggtccgg cgcaaggtcc
   413821 tgaaagccgc tggggagctg ggttaccgcg tcaatcgcct agcgcaggtg ctgaacaatg
   413881 accgatccaa cctgatcggc gtggtcggcg ccaatctctc ctcgcctttc atttcgaagc
   413941 agctcgacct gttgagcatc gggctcctgc gccagggtaa gcaatgcctg cttctgaacg
   414001 ccgcggacgc gcgacaggac attgcgcctc tgatcgaact ccttttcgag ttccgcgccc
   414061 aggctatcgt cgtgctctcc ggggaacccc cgggatcgat cgtcgacgaa tgcattgcca
   414121 atggcgtgcg tctcatcctt atcaaccagc gcctcgatcg cacggatacg aacatggtgc
   414181 tgagtgacga ttcgcatggg gcggacctcg ccgccctgcg gctgatcaaa gcgaattgca
   414241 gaaaggtcgc ggtcgtgacc agcggcagcc agacccccgc ccagctgcgg agggccaacg
   414301 cgttcacgca gcgaatgcag gccgagggag tggaggtcgt cgcctggtcg ggcgggccga
   414361 cgagctacga atccgggctg caggcgggac gcgagcttct ggccgacaag gcgatcgacg
   414421 gcgccttctg tgtaaccgac cttctcgcgc tgggatttct cgatgccgca cggctggaaa
   414481 tgaaccgccg cgttccgcag gacatttcga ttctcggctt cgacgacatt ccgcaggccg
   414541 gctggaagag ctacgaactc acgacggttg cacagtcctt cgaatcgctg acggagaagg
   414601 tcctttccgc tctcgacagc gacgatctgg aaacgcggct gcaggtcgtg ccggtaacat
   414661 tagtggagcg gcagacggcg cgctaggcta gaccaagcac tgccggacgg aaaaccgctc
   414721 cacacttttc ctggaagtgc tctgacgtca cacggcttga cggatgcggc tgtctatgag
   414781 gaggccgctt ccgaccagaa tcggatgggc gaccgaggcg acatgagcgt tgatccgctt
   414841 caggtcacgc agcatgtcga gatgcagcga gctcgtctgg atgctgtcga gccgcccttc
   414901 gcgaaggcgc tgcaaatggc attcggccga ttgcttctcc agccggcgca cctcttcctt
   414961 cacctccacg agacgccgcg ccagctccgc atcgccggtt gcaaagactg cctgcgccat
   415021 gcgcagattg tcgagcgtga tcgcgaagag cctcccaagt tcgccctgcc cgtcttctga
   415081 aaaacgaagg ccgaggctga tcttcttggc gatctcagga tgcagtccct tctcgatgat
   415141 gtcgccgata tgctccagat tgatggcgta gtcgacgatt tgccgggcgc ggcggtggtc
   415201 ttcgtccgtc atgccatcct tgccgacctt cgagacatag agctttatct cgtgctgtat
   415261 ccggtcgacc cgaccttcga gcaggctgat atcggcaagc cgcgataaat cgttgcccct
   415321 gagtgcctcc agcgcccgaa cgagcatgct ctcgatcagg tcgcccaccg acatgacctc
   415381 tcgcccggcg cctgcaagtg cagcaacggg ccgcgcgagc gcttccatat ccagatagcg
   415441 cggcccgttc tcgctttcgg cctcctccgg gatgaggctg gccgtcagcc gataaaggag
   415501 aggcgataat ggaaaggcgg caagcgccac ggcaaggttg aagagaagat gggcgtcaac
   415561 agcgagcttt tgcggcgaaa gacgcgccag ttccataaga tacgcgccgt aaccggccag
   415621 cggcagggcg atggcgcagc cggccgccct gacgatgagg ttgccgatcg taacacggcg
   415681 cgcgctggcg gaagcaccga gcgttgcgag caccggcgga acggcgccgc caagattcgc
   415741 gccgaggaca aggacgatga cgagtgcggt cgacaggccg ccggtcgccg ataacgacag
   415801 gatcagcacg acgatggcaa ggctggagga tgccagcacg gcaagcccgg cggcgaagaa
   415861 cagagccacc ggccaggcgt tttccagcat cgccagaaag gcgctgagcg ccggcgactg
   415921 ccgcagcgga tcggtagcat ttgcaagaag atgcaaggat agcagcatga ggccgatccc
   415981 aacgatggcg ctgccggcgc ccctgcgcgc gctggaccgc gtccgggaaa gggcaacccc
   416041 cgcgacaatg agcagcggcg acagccagcc gaggccgagc gccacgatcc atgcggttgc
   416101 ggccgtgccg acatttgccc ccagcaagac gacctgcgcc atggccggcg caatcagctc
   416161 cttttccacg aaggaggcga ccatgagcgc cgttgcagtc gagctttgga gggcgatggt
   416221 tgccacgaac cccgcggcga aggagcgcgc gccgccgcgg gtgccggcag caaggccggt
   416281 tctcagccgt gcgccccagg ctctcgacat gccgtccttg acctgtccca atccgtagag
   416341 gagcagcgcc accgcgccga aaagattggc cccgacaatc accgattcca tgagtccacc
   416401 ttatttgcct gtcgactttg ccgacgcgaa cccgttcagg gctacccagt cttccgttgc
   416461 cgatcacgcc gaagcgtctt gccgggcggg atttgactgg acgacgatgt gcgcctgact
   416521 attgcccgcg cgttcgagaa agagacccaa tgctcccagg aatatggcga cgaagccttt
   416581 ctccggactg tcgtggcagg tctgtggctc gcatccgaac cggtcggcga gaaaccgata
   416641 gagaggcagc cgcgactctt cgatatgcgc caaagcgagc gatgccccct gccggagaca
   416701 ataccagtcg gcgacgagtt ctatcattgg caggcgtccg agctcggcaa tgtcgattgc
   416761 cgaagcctgc cccagagctg agagctttgg cgcgctgccg gcggactcgc cagtgaagag
   416821 acacgcgatc tcttccagtg tgaggtccgc cacccgctcg actattgccg ggggccactc
   416881 ctccgggaaa tatcggtggc tgaccagcgc ccgcttgtgc gccctgagaa atgctccgta
   416941 gctgggggct gagaaggcgt cgtccggttc ttcaccaagc agggcggcct ctcgctcata
   417001 ggcgttccgg agccgcggat ggaccggtaa tcccgacaat tccaccgtct cgactgcaac
   417061 gttcccctct cccggatggg cgattttgaa ggccggcgga aaggcgacga gcgatgggac
   417121 cgcgacattc gtcagtgatc ggtcgccgct gccgcggcgc gtgacgcctt ccacatgaag
   417181 atgcccgctg aaatggagcg acagtccggc cgccagcagc gcgcgttcga ctgcccttcg
   417241 cggtgtgcgc cgggcaatgt tggtctcgcc gaaaagcgcc ccctcggcgc cggtcgcacc
   417301 gtcgaaagag tcgagcaccg gatagtgcga aaaggcgagc agtgtttttc cgagcctttc
   417361 tgcccgtgcg cagacatcgg caatccacgg gatgacgaaa ggcttacagc ggagcatcgc
   417421 gttccatccg cccgaggtgc tgtcgatgaa ggccgcctcg tcgccccatt catagacccc
   417481 gttcacgggc tcgaagacat tggcgtcgat catcagcagc catagaccgg gctcgggctc
   417541 gaccaggtag gacgcgtcca tcatgttgta acggttcctg ccgtccggcg atgcaacctc
   417601 gtattcgcgg tcctccgcgg catcggacat accgaacggg gtctcccaat ggagatattc
   417661 cggcttgcgg aagtagccga agccagccat cggatcgagg ccggccgggt acccttcaca
   417721 atacatgcga tcactgaccg taacgccgct gccggcgcgc ttcacgtcgc tggtgacgag
   417781 aatgccccga cctgcgcagt cgaggaattg cttggtgtga tgcctgccct gcggaccgaa
   417841 gatgtcgtga ttgccgggga gcgcatagaa cgacatgccg aaggcggaat gctcgtcgag
   417901 aatgttccgg agcgcgccgg tggtggcgcg ctggccatca tccgtgtaat ccccgagcag
   417961 gacgacgtgg cgaatgcccc gccggcgcac ttccgcgagc gctgccagga acgcgtccgc
   418021 gctttcgttg aagacgcggg tcgatttccg ggtctctgcc cagctgcgca tcgtgatttt
   418081 ccggccctcc acctccaccc ggtcgaagcc gaaatctgct tcgaggtcat ggaaatgcgc
   418141 gtcggcgatc acggcgactg ccggcagcgc acgtttcagc attgcgggtc cccgtgccgc
   418201 gcgcgctcga tgaggtcgat ccaggcggag gccttccttg ccgcctcgta gagcatcggc
   418261 ttcggcgttt cgaaccattc gtcttgcatc aattgcctgc gttctcggat cgccgccacc
   418321 gcatcgtcca gggtcgggta aagctccggc tgttgcttgt ggaggaagag cgaaacgagc
   418381 gccacggaac ggcttcgccc gccccggcaa ttcacgagaa ggttcccgcc gtcccggaag
   418441 ggataggtgg gccgtttcgg catcgattgg cgaagtgcgc cgtcgagtat gtaataggcg
   418501 cccagcatca tcgtttcggg gctgccctca ccatcgatca taccgagctt atagtagcgt
   418561 attcccgcga agccggccgc caggcgctcg acatccggct cgtcggacgg cgtctcgaca
   418621 taattgatgt cgagattgat agcgcagttg acgacggtgg tgatgccgtg acgtcgcaga
   418681 agaccgaggt cacgcgcgcc ctcgctgccg ccgatataga gagcggaacc atgcggtccg
   418741 agtccttcgg ctatcgggct gatggcaggt cggtcgtgga caggtgcgtc cattcttttt
   418801 cctctttgcg ggcgacgccg cgtgatcttc aatccacgaa ggttgccgga caggccggag
   418861 ccgtctgccg gcaggcagga atcaccgctg cgtccaacgg tatattcgag gcgcggctcg
   418921 tctccgaagc aagagccggc gccacggcaa gagccggtcc cccggcgtcc aggctgccga
   418981 tttcaagata gggacagacc accccgcccg cttcgctcac gagtagcagg ccggcaaggc
   419041 aatcccagga attcatatgc agttcgatat agccgtccga gcggccatcg gcgacatatg
   419101 caagggccaa tgcgccggaa ccggcccggc gaacatttgc ccccatgccg agcagcgctt
   419161 ccatcacgcc gagatatgcc gtgttcggca cgcgcatcga ccagcccatt tccagagacg
   419221 cggcatcgaa gcgggccgtt tgcgcgacgt ggatcggaac cccgttccgc gtcgcgcctt
   419281 gtccgcgtcg cgcgaaatag agttcgtcct gcgccggatt gtagatcgcg gcgatttcgg
   419341 tagacccgct ctggacaaag gcgatcgaga tgcagaaatg cggaatgccc cgtgcataat
   419401 tcgccgtgcc gtcgatgggg tcgacaaccc agacccgctc gcttatcgct cccccaccct
   419461 cttcgccgaa gaaactgtct tccggaaaat gcgcggcgag cgcgcaacgg atatgcgcct
   419521 cggaggccgc atccacttct gtgaggaagt cttgggggcc tttcatggag acgcttcgtc
   419581 tcccattgcc cagaaaccct ctgagcacca atgcgccggc ggaacggatg acgtcacggc
   419641 acagttctgc gcgaccatgg aggtcatccg aaaaaaactg tcgatccact ggcttccacc
   419701 tgctcattgc acacgcgcgc aatattgcac acgtgttcat tacagacaag cccgttcgga
   419761 tcaggaactg ctacgtttga ttaggtgctc acgatcacgt tcatggttct aggtcggttc
   419821 gtcctaggct cgtcatgaac gtgatcgctt gtgatggcta gcgcgggatg aggagaagcg
   419881 tgtgcacttt tcctccttcc acgctaaccc ttgatgaagg cgagcagatc cgggttgatc
   419941 acatcggcat gcgtcgtcaa catgccgtgc gggtatcctt cgtagacctt cagcgtgccg
   420001 ttcttcagaa gtttgacggc aagccgcgcg gagctgtcga tgggcacgat ctggtcgtcg
   420061 tcgccgtgca tgacgagcgt cgggacctcg atcttcttga gatcctcagt gaaatccgtc
   420121 tcggagaatg ccttgatgcc ctcgtaatgg gccttcgcgc ttcccatcat cccctgccgc
   420181 caccaattct ggatcgcgcc ggttgagacc ttcgcgtcgg ggcgattgaa gccatagaag
   420241 gggccactcg gcagatcgag gaagaactgg gagcggtttg ccgcgagctg agcgcgaaga
   420301 ccgtcgaaca cctccatcgg aagcccgccc ggataggctt cggtcttgag catgatcggc
   420361 ggcacggcgc cgaccatcac gagcttggcg acacggccgg caccatgccg ggcgacatag
   420421 gccagagcct cgccgccgcc ggtggagtgt cctatgtgga tggtgtcgcg caggtcgagc
   420481 tccgtggcga gtgccgccac gtccgccgcg taatgcgcga tgtcatgccc gtcgcttatc
   420541 tgggtcgagc ggccgtggcc gcgccggtcg tgggcgatca ctcggtatcc cttgctcagg
   420601 aagtaaagca tctgggcgtc ccagtcgtcg gaggaaagcg gccatccgtg atggaacacg
   420661 atcggctggc cggagcccca atccttgtag aagatctcga caccgtcttc cgtcgtgatg
   420721 aagttctttg tcatgggaac cgctcctttg ttttggttca tggggtcttt ttccgcggcg
   420781 aaggctgtcg ggacagccat cgccaacgaa actgaggcgc ccgcaagcag cgcttgccgg
   420841 cgcgacaatt gaagagaatc gatcatgttt gcctcttgca gccgtcactg cgttttgcac
   420901 gtccaggggc gctggcgttc cgccctctcg tcacttgccc ttgatatgcg ggcggttgat
   420961 tgccaaaaga tgctgtacgg cgggaggctc caacccctga tgataggcgc ggacttcctg
   421021 ctgaacatcg gcgtccgcct tcgacacgcg cctgtgctgc cgcatgtgtt cggcccagga
   421081 ctccaccgtg aaccattcga cgacgcggct cggatcggcg gcatcctcgg tcacgcccca
   421141 gccgtaggcc ccatcgcggc ggcgctcgtg cgagaggctt gcaagcgctt tcagaaaggc
   421201 gggccggtcc ttcctgtcga cgatgtattc gatcaggatg agcacggggc cgcggtcgtt
   421261 ctcaaccggc tgagccgtca gcggttccgg ccagtgattg gagggcacaa gctcggcctc
   421321 gcctctgggg agctttaccc tatgaaagcc gagcccgaca cagagaaggc cgatcgcggc
   421381 gatgccgagg gccgacggga cgccaactgc ttcggcgatc gcgccccagg caaggcttcc
   421441 cccggtcatc gcaccgttga agacggtcag atagacggca agcgagcgtc cccgcaccca
   421501 attggggagg atggactgcg ctgtgctgtt caacgtcgtc agcgccgtga tccaggcagc
   421561 gccgcaggcc agcaaggccg cgacggccgc ccattgcggc ggagcgagcg aaagtacgcc
   421621 catgacagcg gcggtgacga ttgcggctgc gagcagcagg ccatcggcat ccagcctggc
   421681 gcgcaggcgc ggcatgacca gagcgccgca gaccgcgcct gcgccgacgg cgccaagcag
   421741 catgccatag aagctggcgt ctccaccgag aagctggcgc gcgacgagcg gcagcaatgc
   421801 ccagatggcg ctcgaaaaag caaagaatac ggccgcgcgg atgaggacga cgtgcagttc
   421861 cctgctcgac cgggcatagc gcagacccgc cctgaacgcg ccgaagaagc gctcggcaag
   421921 cgcatcgtcc tcaggcgtcc cgcgccgcca ccagagcagt gcagcgacga cgaagacata
   421981 agtgatgaca tccaccccgt aggtgaccgc agcgccgaac caggccagca gcagaccgcc
   422041 gagcgccggg ccgatcgcgc gcgaaatatt gatgcccagc gagttgagcg ccaccgctcc
   422101 tttgacgtcc tgcctctgca cgagttcagg cacgatcgcc tgccatgttg gtgcgacgag
   422161 agcggctccg atgcccccaa tgaaagtaag cgcaacgagc gagctgacgg actgaagccc
   422221 catggcggag agcgtgagaa ggcaaagact ggcggaagcg agaagcaatt gaacggcgat
   422281 caggaacttt cgccggtcga ggatatccga aagcactccg gccgggatgg cgagcaggaa
   422341 aacgggaagc gtcgccgcgg cctgtacgag cgaaaccgcg gcgggcgtcg ccgaaagttc
   422401 ggtcacgagc caggaactgg cgacgtcgcg gatgaagctg cccgtattgc ctatgatcgt
   422461 tgccacccaa aggacggcaa agacctgctg ccgcaacgga gcgaatgtgc ccgtgccctc
   422521 gagacccgcc gctttcatcg gaagctcctt cttgccgccg gacgacggcg gggttcatac
   422581 agggcgacaa ggacgaaggc gccgacgaga ccgaaatgct cgaaaaagcc gttcatcgcc
   422641 atggaccgct ccaagcccgg ttgcaaatcc cagaaacgga atgcgatgaa ggtcgtcgcg
   422701 aaggtgaaga gcgcaagcgc aagcgccgcc gcccgccgat agaagccggt aaggatgagc
   422761 gccgacatag agagctcgaa cacgatcacg ccgacggcaa agaatggcgc gggataaagg
   422821 ccgaaatggt ccatttcggc gatcgcgccg ctaaaatcga aaatcttgat caaagggccc
   422881 tgaatatagg cggagcagag ggcgagcagc gccagaaaat gaagccccga cacggacgac
   422941 ctcaccggtc gggcgtcgcg caatgaaatg ttcgtcatct gaagttccct cacacggccc
   423001 agcaagagca gccaagcgcg ccgaagaacc ctttcaggtc tgcaaccggc agtctcgatg
   423061 tccaggcgcc ggcatggtcg tgcccatgga ccccgcaatt gctggcgcag ccgcaggacg
   423121 cgattgccgt tcgcttcagc gaatgccttc ccgcgccctc cggttcgccc cacgccgcat
   423181 agccgccata gttccttacc ggcgaccagt cgggcatcgc cggcggcaga gggttctcgt
   423241 cgaggctggc gaaatcgttt gccgcataga cgatcctgcc cccgaccatc gtcagatcgg
   423301 cagtcagaaa cgagatctcg tcctcggcac aggtgaaata gtctttggcc ggcacgataa
   423361 ggtcggcgag ctgccccttt tcgatgcggc ccttccggcc ctcctcgttg gaaaaccatt
   423421 ggactttctc ggtccacatc cgcagcgccg tttcgcggtc gaggcagttg gcgcgcggat
   423481 agagctgcat accgccgacc gtcttaccgg tcaccagcca ggaaagcgaa acccagggat
   423541 tgtaggaggc gacgcgcgtg gcgtccgtgc ccgcggagac cttgacgcct ttatccagca
   423601 tgcgcgcgac cggcggcgta gcttcggcgg caccatggcc atagcgttcg acgaaatact
   423661 cgccctgata ggccatgcga tgctgtaccg ctatgccgcc gcccagcgcc gcgatgcggt
   423721 cgattgagct gtccgagatc gtctcggcat ggtcgaagaa ccagttgatg ccggcaagcg
   423781 ggatgtcctg gttgactttc tcgaagacgt cgagcgcacg gctgatcgtc tcgtcgtatg
   423841 tcgcgtgcag gcgccagggc cagcggttct ccgctagaat tcgcacgact tcctcaagct
   423901 caccttccat ttcgggcgcc atttccgggc gcggttcgcg gaaatcctcg aagtctgccg
   423961 cagagaagac gagcatttcg ccagcgccgt tgtgacggaa gaagtcatcg ccctgcttgt
   424021 attttacgga ggacgtccac ttgagaaagt cttccttctc ctccttcggc ttctgggtga
   424081 agaggttgta ggcaagtctc accgtcatct gcccttcgtc ggcgagcttc tgaatgacgg
   424141 cgtagtcgtc tggatagttc tggaagccgc cgcccgcgtc gatgacgctg gtgatcccga
   424201 gccgattgag ctcgcgcatg aagtgccgag tcgaattgac ctgatattcc aatggaagct
   424261 tcggtccctt ggcaagcgtc gaatagagaa tgcccgcatt cggcttggcg atgagcagcc
   424321 cggtcggatt gcccctggcg tcccgggtga tctcacctcc gggcggatcc ggcgtgtcct
   424381 tgccgtaacc aaccgcgcgc aatgccgcgc cgttgagcag tgcccggtca taaaggtgca
   424441 ggaggaacac cggcgtgtcg ggggcgatcg cgttgatctc gtcgatcgtc ggaagccgct
   424501 tttcaatgaa ctgatgttcg gtgaagccgc cgacgacgcg cacccattgc ggaggcggcg
   424561 tgatcgccac ttgccgcttc agcatgttca tggcgtcggc gagagagcgc acgccgtccc
   424621 agcgcagttc catattgaaa ttaagcccac cgcgcacaac gtgggtatgg ttgtcattga
   424681 ggccaggcag gacgcgcttg cccttcaggt cgacgacctt cgtgtccggc ccggcaagcg
   424741 ccatgacctc ttggtccagc ccgacggcaa ggaacctgcc gtccttgacg gcgatggccg
   424801 tggcgttcgg tttcgcggcg tccagcgtgg tcaccagacc acggtgcagg atcagatcgg
   424861 cgctcatcgg cttgtctcct gaggtcgaaa cagaattggc ggcgcgcgcc ggtgaaatca
   424921 ggcccgggag cgccagggag gacgctgcac caagaaaact gcggcgcgtc ggcatcagct
   424981 gagctccgtg ttggctggac gatcacgcat gccgccatca tctgccccgg tcggcaaatt
   425041 gccgaaaaca tgcggggcgc agcgactgtg gacccaggaa actgttaccg gattgcccga
   425101 taacaggcgt ttgacgagcg gcaccgcctg ctcgccgacg aggattccca ggagcccgac
   425161 cagcgcgatc accggcggtg cgggagagcg aatgttgaga aggctgtaga tcacgccaac
   425221 gagcagcccc gctccgagcg aaaggagata catcttcatc gtcgcttcct ttgcatcacg
   425281 ataatttcag gtcggatcga cgctccgacc gcaggcgcgg ccggagcaga ccagcgcggc
   425341 tcagtgcccc tcagaagcgc cgaacatcga cttggcatag atgatgccga gaccgtaggc
   425401 gccgccgaac ttcctggcga tgccggtggt catctcgtag ctctcggtac gcgcccaatc
   425461 gcgctgcagt tcgagcatgt attgcaggga ggtcatcggc ctgacgcctg cctgcaccat
   425521 gcggtccatg gcgcgctcat gcgcctcgtc cgacacgtcg ccgcaagcat ctgcgatcac
   425581 atagacttca aagccctggt cgagcgcgga aagggtcggg ccgacgatgc atacggaagt
   425641 ccacaggccg cagaagacca ggcgcttcct gccgatgcgg ttgacctcct cgatcactgc
   425701 cgcgtcttcc caggtgttca tggaggtgcg gtccagaagc gcctgtccgg ggaacgcatc
   425761 cgtgatttcg gagaacatcg gaccggagaa agtcttctcc gcgaccgtcg tcagaacagt
   425821 cgagacgcca aaacccgccg ccgcgtttgc gacgagcgcc gcattgtttc gtaacaggac
   425881 cgcgtcgatc gatttcgtcg caaaggccat ttgcgactga aagtcgatca tgatcaacgt
   425941 gtggtcattg ggcgaaacga ggaggttccc gggggtcggt gtcgcgttca gggtcatggt
   426001 ttcggcctct ttccgttggc tgccgaattg cagcttgaga ggctgcgaca atggcaggag
   426061 cggccgtccc gttcttgtag ccgaagacac ctttttgaag attttcatcg cccgctttca
   426121 cgactgccgg tgtcttctcc acacgcccgg cgtcgcgccc atcgcctgca cgaaggcacg
   426181 cgtgaaatgg ctctgatccg aaaagccgca aagggtggcg atttcccgga gcggcgcttg
   426241 cgtgaactcc agcagatgga tggccttctc tatccgctgt tgcgacagcc actggtgcgg
   426301 cgtcttcccc agagtttcgc ggaaggcgcg caggaaggtg gcctgcgaca gctggcatat
   426361 cccggcgagc tcttcgacgg tcaggtctcc ggccagtctg ctctgcgcga gatccttgag
   426421 caacgactga gaacgcatgg aaagcctgcg ccctttaccc gccgcgcgac cgcgaccgtt
   426481 cccgtactgg cgcacgagat ggatgcctat ggcggcggag agctgatcga cgaagagcgc
   426541 gcttctgccg gcctgcccgt cgacggttgc aaacagtgcg cccagcatgc cgccgagcac
   426601 cgggtcagcg tgtcccgcaa cggaattcaa ttccgtgaca cctttgatgt ccgccccatc
   426661 ggtgatccgc tcgagcgcgc tatggctgac ctcaaggagc atgaagtcga aagaaccgtt
   426721 gaggtctgcc cgataatcgt ccgaaaaggt tctcacatag atcgaattct cttcgaaatc
   426781 gtggaccgtg gaatgatgct cccggattat tcgtcgccga tggccgcccg acgccgaaac
   426841 acctatcaga tagccacgac cggtggccgg cgtgctgacc cggccggcag gtgccctcgc
   426901 ggaacgcttg cggtgaaacg tcatgttgcc gccgtcgatc gtgcggtcct cgtccagctt
   426961 ttccacggaa cagccaaggc tgtcgcgggg gcgcgggccg gcgacgtctg aagaagcgtt
   427021 cgtcatgccg tcttggtcct gcaaattgag ccacctgtca gctggagcgg gatgaggaaa
   427081 gctggccggt tttccgcctg catcccgctc acatcatcgc ttttgccaag ccggcattct
   427141 tgtatgaaac acacgcgttt tgaaggatct gagccatctg cgctcaggcc ttcagccgga
   427201 gagctgctcc attgctggcc gcgcgcaccg gttcttccgt ctgtagcgcg caggcgtctc
   427261 gcccgtcaga ccagtgaaga cccgcgtcag atggctctga tccgcgaaac cgcaggcgat
   427321 tgcggcttcc gcgatcggca catcctgaag caaaagctcc ttcacgcgcc cggtccgata
   427381 ttcgctcagc cacctggatg gcgtgcgccc gaaactctcc ttgaaagcct tattgaaata
   427441 gctgcgcgac agctcgcaaa ggcgtgccaa ctctccaagc gaaaacggtt tattgaagtg
   427501 gttcgcgaga aattccgtcg caagtctttc ctgccagggc gcaagggtcc cctttttgcc
   427561 gatcggaaag tgcagcccgc catatgtctg gctcagatgc gccagcacgg caaggttgat
   427621 ttgctccaga aaaagggaac tggcagtttc gggactttcg agcgacggca acagcgcctg
   427681 ggcaagtccg tacatcacgg gatcgatgcg cccctgcaca gaggcaagcc ccagatattc
   427741 gttccgcccg gcctgcttcg caaaggcgct cattcgggca aatggaattt gaaagcgaat
   427801 attgtcgaat ggcgaaagat gatgacactg ccagcgatcg cgcagatcgg tgatcgccag
   427861 agatgccctg gagtgcccgc cttcgtaaac gagcttgcca gccttccaca gtcgatgggc
   427921 ttcaaagtca cgcagttgaa cgatcacact gaatgcttcg gcacagggtg tcgccggtgc
   427981 ggctttcaga tcgtaccggt cggaacagac tctggtcacc gaaatatcgc cggaagtgat
   428041 cgatctgatg atcgggcctt gtgaatccac ggcattcgat tcctgatgaa gggccatcgg
   428101 tgtgggtctc cgatttccgg tttggcgcgc tacgcggcct gatcttgctg cggattcgca
   428161 gctatctgtg actggataca atgagcagga gcccactacc atacgccacc tcatcttcat
   428221 gtgacagccg tccaacccgc cctctcagag caatgccaga ccgctcgcac ttccctcatc
   428281 cggagtttag ttgagccatc gtccgcgcca atcggaagga gaggttcccg tggctctgcg
   428341 aaaggcacgg tcgaattgat ccacgtcgct gaagccgcag cgcttcgcca cctcgctcaa
   428401 cgtcaaggcg cgtgaggtca ggtattgttt cgcccggacg atcctgtgac gcatcagcca
   428461 ctgggacggg gtcaagccgg caacgtcgct gaagccattg atgaagtccc gcttggacag
   428521 accggccgcg gcggccgcgg ccgcaaacga gaagtcttcg gcaaaatgct cgatcatgaa
   428581 gtccttggcg gccttttcct gccatacaga caggcccgca acgccgccgc gagcctcgcc
   428641 gggatcggta taggagtgaa gcaggtgcgc acagactgcg attgcaatat gctggaggac
   428701 tgcattttgg ccgcggccct gttcgtcgaa gaagggaagc agggcggtgc ccagatttcg
   428761 catgacgtca tcgtcctcgc cccttcggca cctgagcccg gttgcccggg gggcattcgc
   428821 gactttggat acttcgcgaa agaggtctcg cggcatatag aaggccagcg aatcgaggtc
   428881 gctcacgagc cggatgctcg cgccatgcgt caggtctacg agacagacgg aaccctcgcg
   428941 gtatcgccgc acctcgcact ctgtgccgtc gccggcaaca tcgcgatgaa gcgcatcatc
   429001 aagatagagc atgaggaaat aggcatcgtc agccggcagc cttaccaacc ggctggccct
   429061 gccgtccagg cggcactgca gacgggtcac tgaaaatttc gccgcatgaa ccggccgcgc
   429121 caccagacaa ggagattccg gctccccgaa aaacacaccc accttctctt cggcgatcat
   429181 tctgaggctc acgtccaact cccggctcgt gcaactggcg gtctgcgtgt gtgatgcgcc
   429241 gccgggctcc tggatagaac ggtttgcgct ccttggaagt ttcgcgagaa tatcaagacg
   429301 ggctctctcc cgaaattccg aggatgcatt acgcgccctt gatcgggaag ctacagagcg
   429361 ggcgcgcggc tttcttgcac cttttaatct cattttgccg caaaacgcac cttttgatgc
   429421 aggccagctg cggactgctg catcgcaatc agcaggaaac cggcgaaacg gatcaaattt
   429481 ccccgtcccg ctctttttgg gcagtgccgg aacagcggcg gcgccttgcg gtttgggtcg
   429541 cttcccagac aggaggacca catgttttac acggacggca agcttcaata tccagtccgc
   429601 gtcgaaaaag ccaatccgct tttcgcacgc gcccttcagc aggcaatcgg cggcatcgag
   429661 ggggagatcc gcgtggcaat gcagtatttc ttccaggcct gcggtgcgcg cggcgacccg
   429721 aagtttcgcg accttctaat gaacaccgcg gcggaggaac tgggtcacat cgagatgctg
   429781 gcgacggcgg tagcgctcaa tctcgagggc gcgccgctca gtctcaaaga gcaagtcgca
   429841 aacgacccca tctccggcgc tgtgctcggc ggcatgaatc tcaagaacct gctgtcggcg
   429901 ggcctatcgg cgatgccggt cgactccgac ggtgtacctt tcgacatgtc gcatatctat
   429961 gccagcggca atatcgctgc ggacatggtg gcgaatgtcg cggcggagtc tactggcagg
   430021 gcgctcgcgg ttcggcttta cgagatgacg gatgaccccg gcatgaaaga catgctgtcc
   430081 tatctgattg cacgggacac gatgcaccag aaccagtggc tcgcggccat cgaggagctc
   430141 ggcggcggtc agggcgtctt ccccattccg aacagcttcc cgcaggatca ggaacagcag
   430201 gagttcagct atgccttcct gggctttcag caggacggca gcgatcccgt ggcgggccgg
   430261 tggtcgcaag gcacatccat cgatggcaaa ggcagcttca aggctgggtc gatcatgcct
   430321 atgggcgaga agccgcaact ggcacccgcc aagccgaggg gcggcgccca aaaggaacag
   430381 atgtaagtcg catgcgccgg acgaatggcg ccggctcata cgatcaagaa ggagggaggc
   430441 gcccacctcc ctccttcttg tgcggcgatg tggttgcggc gctccaaagc gaagaccgcc
   430501 aaggcattct aatacgtatt tgtaaaattg aatttgcata tccttgcatt acatgtagaa
   430561 aatacgtcat ctaagatgac aacaatggga tctcatcgcc ttcttatgct tgtgattctc
   430621 gccgacgatt tgacgggcgc tcttgactcg gctgccccgt tcgctgggcg cggccttcat
   430681 acggaggtcg cactcgcgct ggaatccgtg gatgccgccc ttgcggacca accggaggtt
   430741 cttgtcgtca atgtgaagtc gcgcgaggtc tccccggacg aggcgcgcat ggcgacgtcc
   430801 gacgtcctga aacacgttcc cgacgacgcg cggattttca agaaggtcga ctcccggctc
   430861 aagggcaata tcgaggtcga actcgacgcg atcaggtata accgcgcgct tgtcgcgccg
   430921 gccatacccg acttcggccg cgtcgtggcc ggtggccatg tgcggggatt cggcgtgaac
   430981 gctccgatcc caatcgccga aaggctcggc cgtcacgcgg aaagtgcatt gatcccggat
   431041 accacgtctc gcgacgatat gctcgctgca gtggaaacgg gcgaggctgc cggatgcgac
   431101 ctgatgatcg gcgcaagagg acttgccgaa gcgcttgctc atcgcatgac cggcggtgcc
   431161 gggctacccc tgatgtcagt ccctcaggag ccgattctga tcgtcgtcgg ttcccgcgac
   431221 ccgatcaccg tcgaacaggt cggggtgctg cgggaagatt acgcggtggg ttatttcccg
   431281 gccgttggcg gcagggtgca gcaagaagca ggccgccctg cggaaatggt gaccgtcatt
   431341 caggccgtcg agggggagat gccgctcagc ccctccgagg tatccgtcaa tctggcggag
   431401 agcgtcgttc cggctttcac cggccgcgcc tcaacactgc tgcttactgg aggcgcaacg
   431461 gccgaggctg tgctggcacg attgggcgtt tcccgcttcc gtctcctcgg cgaatgcatg
   431521 ccggggatgg cgctggcctt tgcagatggc cgttatatca tcaccaagtc cggcggattc
   431581 ggccggcggg acactctgag cgacatcgcg aggcagattc tgggggaggc gagatagacg
   431641 atgggactgc aggaagggac cccccgcaag ggcctgcccg acatcgtgtt cgaaagaatg
   431701 caccgggcga tcaagtccgg cgcttataag cctgacgagc gtttgccgac cgaacatgag
   431761 ctggcgacgg agttcgaggt atcccgaccg atcgttcgtg aggcattgcg gcgcctcagg
   431821 gaacagggac tcatttactc gcggcgcggc gcggggagtt tcgtgcgcgc cacgggactt
   431881 cgcgaaccgc tgggcttcgg tcagctggaa aacgtcgccg atctcctgaa ctgctatgag
   431941 ttccggctga cactggaacc cgccgccgcg gccgccgccg cgctccggca cgacgagacg
   432001 agccttgcag cgatccgccg ggcgctcgaa ctgctgcgtg acgccaccaa tcggcagtct
   432061 caccgcgagg acgctgactt ccagttccat cttgcgatcg cccgcgctgc ccagaacagc
   432121 tacttctcga ccgccatgga ggcgctgaag gaacacattg ccgtcggcat gaagttccat
   432181 ggcatctcgg tgaagcgcga ggcaagcggc ctctcgcgcg tgttcgcgga acacgaggcg
   432241 attgccgacg ccatcgccgc cggcaacgcc gaagacgctc gcatattgat gctgaagcat
   432301 ctgaccgggt cgcgcgaccg cctgttcctc gcctcgcagt agtctggatc acgatgtttt
   432361 tcaggcggga ttggccctga aaacatcgtg atctattcca aagtgctgga gcgtagccgt
   432421 ttcgtgcctg gcaggtgtgt ctgttttttc atgtcatcac gcctggacga gagcggggcg
   432481 aaaaaagtgc gcacggtttt cgcccgcatc cgctctaacc tgtgagaatc gatcacgttc
   432541 atgattttag gtcgttccgc ctgaaatcat cttgacctag tcagatacag cgcgttcgtc
   432601 gctcgcccgt cagagcgcca tacacaattt ccgcgcctcg ccttacgccc tacagcgccg
   432661 tgcgtcttat aagacgcaca aaggtcgctg tagcacttcg atctgctgca tgtttttgtc
   432721 cttcaatcgg atccgattaa aggatcatgc aataggctaa aatgccgccc gatagatctc
   432781 cagaacgtcc gcctcgctca tgtctgcggg attgttgtcc atgagccggc ggatcgaatg
   432841 ggcatcggcg gcaaagcggg gcagatccgc gcccttggcg ccattggcgg ccagagacat
   432901 ctctatgccg agaccggcgc agaagtccct tgcggccgag agcagatcac gctgcgacag
   432961 gccctgcccg aggccaagcg catcggcgac ctcggccgtt tttgcggaga cgaccggctg
   433021 gttgaaggca agcacatgcg gaaagatgat ggcattggcg aggccgtgcg gcaggtgcag
   433081 gagcgtgccg agcggatagg atatcgcgtg ccccgccgcc gtgttgacgg ggccaaggca
   433141 gatgccgcca taataggaag cgagcatcat gccctcgcgc gcctcggtat cttctccgtc
   433201 ccgcacggca cgggcgagat atttgccgac gaggttgaac cccatgcggg caaagccgtc
   433261 gatcatcgga tgggacttgc ggttggtgaa ggcctcgacg caatgcgcca tggcatccac
   433321 cccggtcgcg gcggtgacgg caggcggcac gctgtatgtg agctccggat cgagtacggc
   433381 aagatcggcg atcatgtgcg ggctttcgac cgcgatcttg ctgcccttgc cgggatcggt
   433441 gatcagtgag cggattcccg cttccgagcc ggtgcccgcc gtcgtcgcga cctgcgccag
   433501 gcgcacattg cggccagcca cgcgatttgg cccggcgaca tccgcaagcg actgtcccga
   433561 atcccagagc accgccacca gcttggcgac atccatcacc gagccgccgc caagaccgac
   433621 gatcaagtcc gggcgggcct tccgggcggc gtccagcgcc gcgtcgagcg tcgcgatatc
   433681 gggttccccc ggaattgcat cgaagagggt tagcttgcca ggaagctgca ggcgctcggc
   433741 gaagcccgat gtgatcggcg tcgcgatgac gagcgtcgag gccacctcag cggcccacgt
   433801 gccgacctga ctgatgttcc ccgcgccgac gacaagccga cgcggctgat gaatcgtgat
   433861 catgacgctg cctttctgct tgccttgccg gccacgagtt tgcgggcata ggcgatcgcg
   433921 gaattcaggt tgccgtgatt tgcgatgccc tttccggcaa tgtcgaaggc ggtgccgtga
   433981 tcgacggagg tgcggtcgat gggcaggtcc acggaaacat tcaccgcagt atcgaaggcg
   434041 acgagcttga tcgggatgtg accctgatcg tgatattgcg caacgaccag atcgaagctt
   434101 cccgaatagg cgcggtggaa cacggtgtcg gccgagatcg gcccctgcac gtcgatgcct
   434161 tcttcacggg ccgccgccac cgcggggccg atctgatcgt cgtcttccgt gccgaacagg
   434221 ccgttctcgc cacaatgggg gttgatgccg gcgaccgcga tccgcgggcg ctcatagcca
   434281 atgcgcttca gatgcgcgtt gccggcccgg atcgtggcaa ggacccgctc ggtcgtggcg
   434341 cggctgatcg cctccttgag cgagacatgg gtggacacgt gaatcacctt gagacgctcg
   434401 gaggcaagga gcatataggc ggcgctcgac ccggtcaggc tgcgcagcat gccggtatgg
   434461 ccatcataat gatggccggc catgttgagt gcctccttgt tgatcggcgc cgtgacgatg
   434521 cagccgatct tgcccttctc ggcatcgcgc accgcgcgtt cgatgaagcg aaaggcagca
   434581 tcgcctgcaa ccgcggagag gcttccccag gcaagcggcg ctccctcgat cggaagatcg
   434641 acaacatgtg gtgcaaggtc gacggcaacc ccgagtgcct tccttgcagc ctcgagcgtc
   434701 gccaggttgc cgtagatccg ggtcgcctcg cggtcctcgg ccgacatttc cgcaagcgac
   434761 ctgaccgtga tctccggtcc aacgccacag ggatcgccca tggtgatgcc gataatgttg
   434821 ctcatcgaat tctcccgtca gtccggtctg cccatccggg cggcagacgg acatatttga
   434881 ttgcacgccg atggaaggtg taggcgatgt gcaggctgcc gtcgtctccc tccaggagcc
   434941 acggatagga catttccttg ttgtggccat cggtcgaatt gttggagagg catgtccccg
   435001 gtccattctc gatcacgatg cgctcgggga aggtacggcc gccgtcgtcc gacaggcaga
   435061 cgcttacggg tgctcgcggc acgccccaaa taggcacgca cccgcccgac ggatcagcgt
   435121 cgggccggcc gtcatcctct ccgagttcgt cgtaaagcga cgcccggcga tcgggcgaaa
   435181 gggccgcgtt cacgggattg cagatcatgg ccaatcggcc gtcgctcaag cgaatgacgg
   435241 cgatggagga attgttgttc ggcacatcgg tcggcgccgg caagctccat gtccgtccgc
   435301 catcggcgct ttcgacgcgg tacacctggt ccgcctggcg gcgacggaag aaggcggcgt
   435361 agccgtctcc gccgactggg accgggctca tatgcacgca accgatcgag tcctccagat
   435421 cggcgagccg ccacctttca ccgccgtcgg tcgaaatgcc gaccgccgcg ttgtcgtggc
   435481 tgccgttcca cttctggccg gggcgttgaa tgcagcgaaa gatgggaagc agccaggcgc
   435541 catcatctct cacgaccagc ggcgcgcgga tgaaacagcc gcgcggcagg tcgagatagc
   435601 gcccctcggc ggcatcgagt ttcgtcggat cgtcaggatc cctctcgatc gcggccatgc
   435661 ggatgcggca ctcgtcctga ttgcccgcag gttgggaggt atggaaaagc cacaaccgac
   435721 cgtcgggcgc cgtgaagagt accgggttct gttcggaatg gtctgcgtcg aagctcagcc
   435781 gctgcggttc gccccatcgc tcggcgcctg gcgcgagcac ggaagcgaag atcgagatat
   435841 cggattttcc ctctagcgta ccgccgaacc aggcacagac gagacttccg tcctcgagcc
   435901 tgtgcagaaa ggccgcatgg ttctgcaccg tgggcgacgg gagcagcgat tccagtctgc
   435961 cgtccctggc ttcccggagc ttgccggtca ttgcgtttgc gatttcctca ggcgtcatga
   436021 aagcctcctg ttgccatgga caatcgcgtt atttctcaag ttgtcaagtt ttctgttttt
   436081 cttttgcaac tcttttgcgg ctgatggatt gcattatatt gttgaaaaca cttatttttt
   436141 taagatcgaa aatttttcgg atcgcaatgg gcgagaaaac aatttgacaa acttatcagg
   436201 aaattggatt gtcggggcaa ttccaggcgg cggaaggaaa aactccgtcc atagacgata
   436261 gctaggaggc tgactgctgc cgatatgcgg cccggaaacg gcacaggtcg aaaataggca
   436321 accgcctgac acgaaattct tagggaggag aatgcaaatg aaaagatcgc tgcttttggg
   436381 agtcctcatg ctgggctccg ccctatcccc cgctttcggg gaatcgggac cgatcaagat
   436441 cgtcctaccg gaagaggcag atctgcttga gccttgcatg gccacgcgtt ccaatatcgg
   436501 ccgcatcatc atgcagaacg tcagcgagac gctgaccgag cttgacgttc gcggcggcaa
   436561 gggcctgatg ccgcgtctgg cggaaagctg ggagcagaag gaggatggca gctggcgctt
   436621 caacttgcgc aagggcgtca agttctccga cggcaccgac ttcaacgcca aagacgtcaa
   436681 gtacagcttc gaccgcgtga tgagcgacaa gaacgcctgc gagtcgcgcc gctacttcgg
   436741 cggcatgaac atcaagatcg acgtcgtcga tgacgccacc atcgatttca ccgtcgatcc
   436801 cgttcagccc atcctgccgc ttctcctgtc gttgctgacg atcgtaccgg aagagactcc
   436861 gatggaattc gttcgcgagc ctgtcgggac cggcccctac gagctgactg actggacgcc
   436921 cggccagcag atcgtgctca ctgcccgcga cgactactgg ggcgagaagc cggaggtcac
   436981 cgaggccacc tatctgttcc gctccgatcc tgcggtccgc gccgcaatgg tccagacggg
   437041 tgaagcagac ctttcgccct ccatatcgca gaccgaggcc acgaatcctg ccacggattt
   437101 ctcctatctc gacagtgaga ccgtttacct gcgcatcgat cacaatatcg agccgctgaa
   437161 cgatgtccgc gtgcgccgcg ctctgaacct tgctatcgac cgcgaagctt tcctcgggac
   437221 gctggtgccc gacagcgccg ttcttgccac cgctatcgtt ccgccgccga cgctcggctg
   437281 gaacccggac gtcaaggtct tcccctatga tcccgatcag gcaaagaagc tcatcgagga
   437341 agccaaggcc gacggcgtca aggtggacac gccgatcacc atcatcgcgc gcacggcgaa
   437401 cttcccgaac gtgaccgaaa tcatggaggc tatccaggcg cagttgcagg aggtcgggct
   437461 tcaggtcgag ctcaagttcg ttgaggtcgc cgagcatgag gtctattatt caaagccttt
   437521 caaggacggg cgcggcccgc agctcgttgc ggcgatgcac gacaactcga agggcgatcc
   437581 ctccttctcg atgttcttca aatacgactc cgaaggcacg cagtcgggct ttgccgatcc
   437641 gaaggtcgac gacctgatcg cccgagcaaa tgcagccgtc ggtgacgaac gcgcaaagct
   437701 ctggtccgag ctcatcgcct atgtgcacga cgaggtggtg gcagatgtgc ttctgttcca
   437761 catggtcggc ttctcgcggg tatcggagcg gctggacttc aagccgacaa tggcgacgaa
   437821 ttccatgctg cagctctccg agatcaagat caaatgacct ggagcaatcc caggaaaagt
   437881 gtgtagcagc tttccgtctg caactgcgaa aaccgcgtaa aagcggccgt tcgaacgaag
   437941 accttccggc ggcgggatac ccgccgcctc atgcaaatcg agggctgcca tgctcagatt
   438001 catccgccaa cgcgcgctcg ccagcctgat ctcgctcatc ggcctgatcg tcatggtttt
   438061 ctttctgtcc cggatgaccg gcgacccggc ggctctgttt ctacccgtcg aggcgtccgc
   438121 cgagatgaag gaccagttcc gggaactgca cgggctcaac gatcccatcc tcgtccagtt
   438181 cgcccggtat gtgggcgacg ttgcgaccgg cgacctgggt caatccctgc gcaaggcccg
   438241 ccctgccctc gatgtcgtac tcgaggcctt cacctggacc ctctggctcg ccatcatcac
   438301 gatgaccctt gtcaccggtg cggcgatcgt cgtcggctcg cttggcgcct tccgctccgg
   438361 cggcttcttc gaccggttct cctcgatgat atcgctcgtc ggagcgtcag taccggattt
   438421 ctggctggcg atcgtcgcca tcgtcatctt ctcgatcaac ttcgcgatcc tcccgacttc
   438481 cggcaccgga tcggtcctgc actggatcct gccgatcgct gttctcttcg tccgcccctt
   438541 cgggatcatc gtccaggtgg tgcgcggcgc aatggtcggc gcgctttcct cggcctatgt
   438601 gaagacggcc cgcgccaagg gcgtgaagtc cggacccatc atcttcatcc acgctctgcg
   438661 taatgcgatg ctgcccgtca tcaccgtggt gggcgatcag gcagcgagcc tgctgaacgg
   438721 agcggtcgtt gtcgagacca tcttcggctt ccccggagtg ggcaagctca tgatcgactc
   438781 catcctgcaa cgggatttca acgtggtgct tgcggcgatc cttgtcacgg ccattgccat
   438841 cttcctcatg aacgtcctga tcgatctcgc ctacgctttg ctcgatccgc gcatccggca
   438901 ctgaggaggc aacgcaaatg accctcgcaa ccaccgacaa cgtcatcgct gcagagccgt
   438961 cgctcctggt ccgcatgatg cgcatgctgc tggcggataa gttcgcgctc tcagcggcta
   439021 tcttccttct cgtcatcctg gccatcgcca tcatcgggcc gagctggctt ggcgatctcg
   439081 ctacgaagca aaatctgcgc ggccggaatc tgccgccctt cgactggacc cgcacctggg
   439141 tctggtggat gggcgccgac gcgctcggcc gaccactctt tgcccgcatc atcgttgccg
   439201 cccagaacac tttgatggtc gccgccggcg ccgtgatcct ttcgtcggtc atcggcaccg
   439261 ttttagggct catagccggc ttctcctcgc cgcgcaccgg ccagatcatc atgcgtctcg
   439321 ccgacgtgat catgtccttc ccctcattgc tgatcgcggt gatcgtgctt tatgtcctgg
   439381 gctcctcgat cctcaacctg atgctggtgc tcgccatcac ccgtataccg gtctatcttc
   439441 gcacgacgcg cgccgaagtg ctggagatcc gcgagcgcat gttcgtgcag gccgcccgcg
   439501 tcatgggcgc ctccagcaag cgcattctct tccgacacat tctgcctgtg gtgctgccga
   439561 cgctgacgac gctcgcaacc ctcgatttcg cctatgtcat gctggcggaa agcgctctgt
   439621 ccttcctcgg catcggcatc cagccgccgg aaatcacctg gggtctgatg atctcgcagg
   439681 gccggcaata tctcaccaac gcctggtggc tgtccttctg gcccgggctt gccatcattc
   439741 tcaccaccat gtcgctcaac ctgctgtcga actggatgcg gatcgcgctc gatccggtac
   439801 agcgctggcg tctcgaaatg aagggcggca aaaatggctg aacatctgct cgaggtccgt
   439861 aatctctcgg tcgaatttca caccgcggcc ggcgtggtgc acgccgtaaa atcgatctcc
   439921 tatcacctcg acaagggaga gacgctggcc atcctcggcg aaagcggctc cggcaagtcg
   439981 gtatcttcct cggcgatcat gaacctcatc gacatgccgc cggggcgcat cagcggcggc
   440041 gaaatcctgc tcgacggcag ggacctgctg acgatgccag ccgaggagcg gcgcgaggtc
   440101 aacggccgcc gggtggccat gatcttccag gatccgctca gccacctcaa tccagtctac
   440161 agcgtcggct ggcagatcgc ggaagccatg accacccatg ggctcgccgg cagcaaggca
   440221 cgcgaggaag gactgcggct ccttcgccgc gtcggaattc ccgagcccga gcgggcaatg
   440281 cgcaaatatc cgcacgagtt ctcgggtggc cagcgccagc gcgtcatgat cgcaatggcg
   440341 ttggcgctgc ggccggatct cttgatagca gacgaaccga ccaccgcact cgacgtgacc
   440401 gtgcaggcag aagttctaaa gcttctgaag gagctgcagc gcgaaacagg tatggcggtg
   440461 ctgatcatca cgcacgatct cggcgtcgtg gcggaaatcg ccgaccgggt ggtcgtgatg
   440521 gagaaaggca ccctcgtcga ggcggggacc gtccgcgaga tctacaagaa cccgcagcat
   440581 ccctatacgc gcaagctcat cgccgccgcc cccggaaagg gcgtgatgca tgagcccggc
   440641 gcccgcgccg agcctctgct cagcgtgcgc gacgtgcgca agacctacgg ctcgttcgaa
   440701 gcactgaagg gcatctcctt cgacctgatg cccggcgaga caatggcggt ggtcggggaa
   440761 agcggatccg gtaaatcgac cctggcccgt gcactgcttc gtctcgacga gccggacagc
   440821 ggcactgcct tgtggaaggg acgcgacctt ttcgcgttat cgccttcaga gctctacaag
   440881 ctccggcgcg acctccagat ggtgtttcag gacccgacgc agtcgctcaa tccgcgcatg
   440941 acggtgtttc agctgatctc cgaagcctgg gttattcatc cggacattct gcccaaggca
   441001 agatggcgcg agcgcgtcgc ggagctcctc gcgcaggtcg gtctttcggc cgaacacatg
   441061 agccgctatc cgcaccagtt ttccggcggc cagcgccagc gcatcgccat cgcccgggcg
   441121 cttgcactcg agccgcagtt gatcatctgc gatgaagccg tctcagcgct ggacgtctcc
   441181 gtgcaggcgc aggtgatcga gcttctcgac aagctgcggc gcgaaatggg catcgccttc
   441241 atcttcatcg cccatgacct tcccgtcgtt cgtgatttcg ccgatcacgt catggtcatg
   441301 cagcagggag aaatcgtcga gctcggcacc atccgcgagg tcttcgaaac gccgcgccag
   441361 gcctatacgc gtgcgctcct ggcggccagt ctcagtcccg accccgacgc caaagccggt
   441421 tgccctgaac cgccggccgc cgacgccgaa attctcattc cgaagcggag ccactgatgt
   441481 ccaagaaagc tttcgtcgca ctcgtcacat gcttcaacga ggacgagacg atcaattatg
   441541 cggcaacccg agcgcaggtg cgccggcagg tcgccgccgg caacaacatc atgtgcgccg
   441601 gcaccaatgg cgacttcacc gcgctcacgc acgaggaaaa gatccgccta accgaggagg
   441661 tggtcgacga ggtcggcggc cgcgcagagg tcatcgtcaa tgccggcatg ccggcgacct
   441721 tcgagacctt acagctcgca cgtgccttcg accggatcgg cgtcagcggc attgccgtca
   441781 ttacaccctt cttcatcgcc tgcacgcagg atggcctgat ccggcacttt tcgactgtgg
   441841 ccgatgccgt agagaccccc gtctatctct acgacatccc ggcgcgaacc cagaaccata
   441901 tagaaccagg gacggcgctg aagctttccg agcacggcaa tatcgccggc atcaaggatt
   441961 ccggcggcgc gcaggatacg ctcgcggcct atctgcaggt ggcacgcgac gtgccgggct
   442021 ttgaagtcta ttccggcccc gaccatctgg tcctctggtc gctgcagaat ggcgccgccg
   442081 gctgcatttc cggcctcggc aatgccatgc cggacgtgct tgccggtatt ctgagcgcat
   442141 tcaatgccgg cgacatcgcc gaggctgaac gccagcagtc catctacact gccttccgca
   442201 ccgaacttta cgccctcggc ttcccacccg ccctggtcaa gcgcgctctc tatctgcagg
   442261 attcctccgt cggcgcctcc cggcagccgg ctttgctccc gaacgacgag caggacgcaa
   442321 agatacgaga gattctggtg cggttttccg tccccatgcc gctctaatcc gtcctctgga
   442381 gagagccttt cctggtctaa atggaaaggc tttcgtgaga ctcgggcagg ccgccgtgtc
   442441 tgacaggagc ctctgagacg gcacgcatcg ctcttacggc gcgccgggga agaagcggca
   442501 cattgcgccg caatgcgccg ggcaacctcg tgacgagcgg cagcagtagc atccccaaat
   442561 agatgctgat tctggagctt ggaacaaggc tctcaaagag cgcgggaccg atgacccggc
   442621 tctggtggac caagtcacgc gttgcattgt gatagctctg caatgcccag cgatagtcgc
   442681 ccttggcctc cgccaactct cgcgcaaggg tatatgcccc tatcacggcc aggcttgtgc
   442741 cgccgccgac tgccggcgcc gggcagtaag ccgcatcgcc gaccagtgcg atgcgggccc
   442801 ggtgccagct ctgcatggtg atctgatcga gcgattcgaa gtaaaagtcc tttgcgcccg
   442861 tcagccggtc aagcaggtgc gccacctccc acgactcccc gccgaacgtc gtttgcaggg
   442921 ctttgatttg tccctttacg tcgtcgtgtt gaaggccaag aggccgggtc ggccgaaaca
   442981 gaaatataac ggcggcgtcg ccgctatgac gaatcggaaa gacaaccacg gtcttattcg
   443041 gaacgacgta gcgatgcacg ccttcgccca gcttatgatc gtctgcgacc gtgtacccgc
   443101 agacatagcc gccaagattg cggctgaacc ggtcttcctc accgaaagcg atatgcctga
   443161 cgttcgagtg ctggccgtcg gcgccgatca ccagctcaaa gtctcgcgag tcgccgcttt
   443221 cgaatgtgac gttcactccg ccggcatgct catccatacc gctgatggaa ttgccgaaca
   443281 tgaagtcgcc gccagcgctc aggcttcgac cgaggatccc cacaagttcg ccacgcatga
   443341 tctcgatctg tttcgaagcg aactgacccg agatccggtt gagttcgatc tcccgcggac
   443401 gcagccccgg cgtaatcatc acaccacgat cgttgcgtgt acgccgctcc tcgagctcgg
   443461 caagcagtcc catccattca aggacgtcga gtgccgtgcc ccaaaggtcg accgcgtggc
   443521 cgcctctccg aagtccggtg gacttctcca cgatggtcgg ccggaagccg tagcgtccca
   443581 accaccaggc gagaaccaga ccggcgatgc cggaacctga aatgagtatg tcttttccac
   443641 gcatggaccg tgcatcctga cataagcgat ctctcgtaga acgcactcga tcgcttttcg
   443701 ctgcaacctt gccttcaagg ctgcaccttg cgtccgcttc gagtccgtcg tagggtacgg
   443761 taccgtaccg tatcttccaa tatcacgcaa attcatttgg ggcataacat gaagcgaaag
   443821 atcaaaggcg tagcgtccgc ggcgaccgcg ctcctggtgt ttggagtggg ggcgtatttt
   443881 ggacgggcat ggtggcaaga gttccgcatg cacgaacgga cggacaacgc ctatgtccgc
   443941 gccgacatca ccgccatcag tcccaaagtc gccggatacg tatccacggt gctggtcgac
   444001 gataaccagg tcgtcgaagc cggcgccatt cttttgcgaa tagacgacga tgactatctc
   444061 gctcagcgag atcgtgcggc tgcgagcgtc gcacaggccg aagcagccgt aggaaatctg
   444121 acacgccgta agagcctgca gctcgccaat atccgcgagg ccgaagcgat gatcgatgtc
   444181 gcccgcgcgg atctcgagct ttcgcgccgg gagctgtcac gagcgacgcg cctggtcgat
   444241 cagggatgga cggcgcagcg gaaccacgat acggcgacgg cgaaagcaca gagtgctcgc
   444301 gccacgctcg ttcgcgccga agcggcggca gcggctgccc gggcgcagct ggcagtgctt
   444361 gattcggaat ctccgcagat ctcggcgcgc ctcgccgagg cgcgcgcaaa cctccgactc
   444421 gcggaaattg ccctttctga aacggtcatc agagcgccgg tgtccggagt tgtcgggaac
   444481 cgaaaagtgc gcgagggcga atatgtccgg cccggcagcg ttcttctgtc cgtggttccc
   444541 cttgacggca tctgggtcgt cgccaatctc aaggagacac agcttgcccg cgtcatgcct
   444601 ggccaacgtg ccgaaatccg cgtggacggt tattcgacga cggtgatcga aggacgcgta
   444661 gacagcctgg cacccgcaag cggcgccgcc ttcagtcttt taccaccgga caatgcgacc
   444721 gggaatttca tcaaggtcgt tcagcgcgtg cccgtcaaga tccggcttga gcccgatcac
   444781 gcttttcagg gccggctcgt cccgggtctg tcggtggacg tcgccataca cctggctccc
   444841 gagcccgagc ggccaccctc ccaaagcaat ccggtcgccg ctggccgccc gacttcatcc
   444901 ctaactgcca ggagagagcc atgacccgct tcgctgcgac gcgccacttg cgaacggctg
   444961 aaagggatga gccaaaggct tcgcttcgac cgtggctggt ccttgtcttc ctgtcgattg
   445021 ccgcgaccat ggatgccgtc aacagcacgg tgctcgtcgt cacgcgcggt catctcatgg
   445081 gcggcacgca tgcgacaccg gacgagattg cctggatcaa catgacctac ctcgctgcca
   445141 agctgaccgc gctccctgca tccgcctgga tgatgtcatg cgcctcgcct tcacgcttac
   445201 tggccggcgc cattgcggcg ctcatcgcca gctcgctggg gtgttccgcc acggatgatc
   445261 tcggctggct catcggctgg cgggtccttc agggcgctgc cggtgcaact ctgctcgtgg
   445321 tcgggcagac gctgctgttt tcgatgttcc cgcggtcccg tcaggggatc gtccaaggac
   445381 tgttcgcctt cgctaccatc atggcgccga ccactctcac gccttcacta cagggctgga
   445441 tcgccgacac gcactcctgg tcatggcttt ttgccgcaaa tgtgcccctt ggcaccgccg
   445501 ggcttttcgc tgcctttctt gcggccgatg ggcaaactac ggtgcgcctt gttcgccggc
   445561 tcgatggggt cgggctggtg ctcttcgccc tatttgcgac cgccttcgtc tttgtcacgc
   445621 aggaagggag ccgctacaac tggttcgatg aaccggaaat catcgagtat tttgccctcg
   445681 gttcggctgc aatcctcgcc tttatggcat ggcaattcac gaagcagggc cgcgaccccc
   445741 ttcttgactt cgttattttt cgcgacgagc atttcacctt cggcttcgtc gtcagcttcg
   445801 tcgcgggctg tgccctgttc ggcagcgcct tcgtcatccc ggcattcgcc accggcgtac
   445861 tcgattttcc acccgcttat gcgggtttcg tcctcttgcc gggtgggccg cttgtctgcg
   445921 tcggacttct cgcggcaggc gggctgatcg atgcaagggg cctcgacccg gccaagccta
   445981 ttcccctagg tatcgtctgc ttcatggcgg cgatgtgggc attgtccggc tcgacatcgg
   446041 ggagcggcct gtcagacctt ataccgccta ttatgctccg aggcctgggg ctcggcctgc
   446101 tcttcgtctc gctgacgctc ctcacgttgc gcgacctggg cccggagatg atcgcccagg
   446161 gtgtggccct tttcaacctt ggccgtcaga tgggtgggca attcgggatt gcttggctgt
   446221 cgacaatcct tgacaatcag aacgcccaga accggacagt actgtcccaa tatctggcgc
   446281 cgggcgagca tgccgtgact gaacggcagg acgctgtggc aaattatctg acatcgcgtg
   446341 gctacttccc cgaagaagcc ggcaccgcag ccactgcggt cattcagaag gccttcgccc
   446401 agcaggtggc gacgctctct ttcaacgcgt gtttcctggc aattgcacta ttgtttatcg
   446461 ccgcggtgcc ggtcctgatc gcgacgaagc tcaccctcgg ccgtctggtg gggcggcacg
   446521 gcaatctgaa gcaagggcca gcctgcctgg agaacacaaa tgagcggaca agcgatctct
   446581 aagcttatcg aatggctcgc cggcgacgat tgtcatcggg cggatgatgg cggcctggcg
   446641 gaaggtctgg gacaacgcct gcgcgctcac gggctgccgc tcgatcgtct cacgctgcat
   446701 ctgagaactc tgcaccctga gatattcggc cgcagtgtgg cttgggcgcc ctcggaaccg
   446761 gtcgaggtcc gagaacgaga gcacggcttc gatcgtacag ccggctttgc cggaaacccg
   446821 attagaaatg caatggaaac aggcgagccg gtgatggtcc gtatcggtgc ttcgaaccgt
   446881 ccgctttggg tcgacagcga cctgttccgg gaccgcgggc tcgttgaatt ctatatcatg
   446941 ccgcttcgca acgccgacgg cacagcaggc gccgccagct tcgcgacgac gcagccctcg
   447001 gggttcacgg atctgcatcg ggcagcaatc gatcggattg cgccggctct gcgcaacgca
   447061 tgtgagcttc gcacgctcag gaggatcgag cataccctgc tcgataccta tatcggcgcc
   447121 agtccggctc gccgtgtgtt ggcgggcgga gttcgccgcg ggcaagtcga gaaacttgaa
   447181 gccgcactca tgctgtgcga cctgcgcggc ttcaccgagc tttcaaatca gctttcagcc
   447241 gagcgggtat tggaactcct gaacggctac ttcgatcagg tcgtacctgc aatcacacaa
   447301 gccggcggcg aggtgatcaa attcatgggc gacgcggcac tggccttctt cgacctgcag
   447361 gatcccgcca cctcctgcaa tgctgctctc gcaagcgctt tcgatgcgct gaagcgcttg
   447421 cagtgctgct ccccacgcgg agttcggctc cacgcaggca tcgctctcca ctacggtcaa
   447481 gcagcctatg gcaacatcgg cgccagccag cgcctcgatt tcacgctgat cggcaccgac
   447541 gtcaatctgg tcagccggat acagggagtc tgcagcgcaa ccgggcaccg gctgatcctg
   447601 tcggagcgct gcgcgcggct tcttcatcct gattgcagca aatcaattgg acgccacagg
   447661 ctcaggggat ttccggagca tgctacgctc tacgttccag cctctcatcc ggcgtccaaa
   447721 aactagaacg ggggaggaaa atatgcgcgg tcccccgccg gcaagccgca cgcattcatc
   447781 gtgacctcgt cagctcggtc ttccggatgc cgtacacaaa aacgtcgacg gcatcgcgaa
   447841 ccgacgagcg agcttccgca ggcgtcggcg gatcgcaaag cccaagcacg accttcaggt
   447901 gcaggtcgtc gcggatcatg cctatgaagt gctccgccag tttcgccgcg gaacgctttg
   447961 gtattcccca gttgtccgcc ccttcctcga ggatacttgc aagagctgca ctggccctgc
   448021 cgggaccgtt ctcgaagaaa gcgcgcgcca cgccaggaaa ccgcgcgcct tcgccgacga
   448081 ctatacggta gagctgcagg gcttccggtg acatgactgc gtcgaggtaa tggcttccgc
   448141 tcctgtaaag caccgtatcg aggtcggcac cggcaatgtt cgcggcgggg aatgggccca
   448201 ttacccggcc ggtgatctcc tttatgactg tcgtaaacag ctgatctttc ttgccgaaat
   448261 agctgtagat ggtccgcttc gaaccacccg ccttcgcgat gatcgagtcg acgctcgcac
   448321 cggaaaagcc cgaactcagg aacacctccg tggctgcgcg cagaaactct tcgcgacggg
   448381 cgtcccgttt cccggagcgg cctgatgccg cttcctggtc gtcctcgtct tcggcaaact
   448441 cttcttcggc catccaattt tccggttctg tgctgcgcaa gtcctgcggc ggttttaata
   448501 tgcgctgggt cgcagaacaa cggcgatacc acgcattact gtcatccggt gcgaattgac
   448561 gtttactttg cttcagccgg aagcccgccg gccggaccgg tagagagccc atccggcaat
   448621 cagcatcacg gccccccaga ggagaaagcc gatgtcccag tagacccact gatcgcgcgg
   448681 caccgtctcg ttgacatggt ggagtccaag cagctgatgg ttgaccatgc cctcgaccag
   448741 gttgaaggcg ccgaagccca taagaaagct gccagccatc agcctggccg accaatgcag
   448801 gcgcctgcgg tgcgcactgc gccacaaaac caccacgccc aggacgacga agatgtatgt
   448861 ggccgcgtga aagaggccat cgaaaaacgt gttcagcttc aggttttcca ggctgtcggg
   448921 gggaaaacct gcgctgctca gcatgtgatg ccactgaagc acctgatgga gaacgatgcc
   448981 gtcgaagaag ccaccaaggc ccagaccgag cagaattccg gctgcggcag ggaattctcc
   449041 gttgccttgt cgggtgttgt ccaatgccgg ccatcctttc agcagcacac ggcaaaatcg
   449101 gcgcgcctca gggagctcga taggctgaat ccgtatcgac ggggttttcg acatatttcc
   449161 cttcaggcgg caccgcgaga tggtcgaagt ctcgcgcaag ctcggcaagt gccatgcgca
   449221 tttcctggcc gcgcatagcg ggtccgtgcc ccgtgacggc aagctcgggc cggaacgatg
   449281 caagcgcctc gaccgacatg cgcgcctttg cccagtccac ggtgtagtac atgggcgggc
   449341 catgcatttc cgggctttgg accgcgacgg cataggccga ctcctgccgc gtcgtaatga
   449401 aagcatctcc cgcgacgacg atccggtcgg cttcgcgcca gagagaaacg tggccgggcg
   449461 tgtggcccgg cgtatgaagc cagcgccacc cgggcatatg cggtacgctg ccgtcggccg
   449521 gcagcggctc tagccaacgg cccacattta ccggtccacg gggaaagagc ggggaaagga
   449581 gcgacatcag ccctcccccg accgaggaat ccggcggagg ataggccgca cgcccgtcga
   449641 gataaggctg ctccaaagga tgggcgaaaa ccgggacatc ccactcatcg gcaaggtcct
   449701 ccagggctcc tatgtgatca aagtggccat gggtcatgac gatcgccgcc ggccgcgcat
   449761 cagacccgaa gcgctccgcc gcagcctgct tgataagcgc tcttgttccg accacaccgg
   449821 catcgataag cacccatccg cggtcgccgc agccgggctc tccgaagaaa atcacgttga
   449881 cgatcgcaag ccgccggtaa gcgaggtccc gcgcaatttc ctgcgtcccg tcgtcacgcg
   449941 ctgcgtcgga ttgcggcttg tcggcgactg ccgacgggcc gagcggtatc tgagccatat
   450001 cgcatctcct cgccaatcag gcctgcctaa cacgtctacc ggtcaatggt tcccggcacc
   450061 tatccgcagg cggttggcgg ttgcgaatag cacgcggcca ggccattcta gtgcccaggc
   450121 tcaatactgc ttgcatggag caaccgctcc accagtatcg gcagaaacga ttgcacggtt
   450181 cagctcggga ttgtattctt tcgatctatt tattaattga tcagtttgat gaaaccttct
   450241 tttcatttcg cctaagctgt tttaatgttc tccacgtcag tagaagcggt cagccgcgtt
   450301 agtatctaac gatacaacat ccggtcggga attgctggca tgcgatcgcg cagaccgcag
   450361 cccgacggac ctttctgacc tcgccttcag caaagttgac gtcgaactcc ggggcgcctc
   450421 gctcacgggc aatcctcgga atttgcccgt gaatcggttt gacggcaact ttggagagac
   450481 tgatgattat cgacattagc tgctacccga ccaagcttgt ggatctggcc tggcggcacg
   450541 atggcgagcc gtttacaggt gagcgcctcc tcaagatgat ggacggccct tattatgtga
   450601 atgggaagcc gcgccgcatc gacaaagcct tcattcagcc gccgcagggc aatacgatct
   450661 acaccgacgg ctacggcgat ctgactggca aggcggcgat ccgggactac atgtcctaca
   450721 ccgtcgagct cgttcagaaa tatccggacc gcttcatcgg ctgcttcgtc tacaaccctc
   450781 gctacggcac gcagaacggc gccgaagaga tcgagcacca cgccaaggaa tacggcttca
   450841 agatggtgca gctccaggcg aacatgcacg cctaccgccc cgaccgggcg ctcgactggt
   450901 tgcgccccgc gatgaggaaa tgcgccgatc tcggccttat cgtgaaggtg cacaccggcg
   450961 acggccccta cagcattccg accgaattct acccgatcat ccgcgagttt ccgtcggtca
   451021 atttcgtcct cgggcacttc ggcgtgcaga cgggcggggt ctacgtcttc gagccgttcc
   451081 agatggcgat ggatgcgccg aacatctatg tggagtcggg ctggtgcctg caatcgcgca
   451141 tcgtcgaatt cgccaaggaa ctacccaagc acaagctcct gttcggcacc gacacccctc
   451201 cgaacgaacc ggggatgtgg ctgcggctac tcgaggtcct gtgccatgaa ccgccgcagg
   451261 gactgaacct cgacgaggac acgctcgagg actacctcgg caacaatatc ggacggatga
   451321 tcggtctcga tccgaccccg cctccacgca gcgtcgaaga ggcgcaggcg cgcctcaagg
   451381 gcgcccatgc cagccttcag ccggcatgac gcttccgcac gcgtgcttca tgaaatcgga
   451441 gaaataagat gattatcgac acccacctcc acccgaccaa tctggtcgac gaggcatggc
   451501 gccacaccgg cacgcctttc aacggcgagc gcatgctgaa actgatggac gggccctaca
   451561 tgatcaacgg caagcctcgc cgcatcgaca tgggcttcat ccagccgccg cccggcaata
   451621 ccggctaccg agacggcaac cgcatgggcc gcgagggcat tcgcgactac atggcctata
   451681 tcgccgaact ttgccagaaa tacccggacc gcttcatcgg caacttcaac tacaacccgc
   451741 gttgggggcc cgaaaacggc gctgcagagc tcgagttcca tgtgaaggaa tacggcttca
   451801 agatgctgaa gctgcacgcc aacatgcatg gctaccggcc cgaccgtgcc ctcgactggc
   451861 tacgtcctgc catgaagaag tgcgcagaac tcggcgtcgt cgtgctgatc cacaccgggg
   451921 atggtcctta taccattccg acgatgttct acccgatcat ccgcgagttc ccgatggtca
   451981 atttcatcat cgggcacttc ggcatccaga cggggggcaa ttattcgttc gagtccttct
   452041 ggatggcgat ggatacgccc aatgtttact gcgagtccgg gtggtgcttc caatcccgca
   452101 tcgtcgaatt cgcgaaggag ctgccgaaac acaagatcgt tttcggaacg gactcgccgc
   452161 cgaacgaacc gggcatgtgg ctgcgcgaac ttgaggtcct ctgccacgaa ccgccccacg
   452221 ggctcgggct ctcggaagac gatctcgaag gctacctcgg caacaacatc gccaagctcg
   452281 tcggcatcga ccctacccct ccgcctcgca atctcgagga ggccaaggcg cgcctcaccg
   452341 acacttatgc aggactgagg cgcgagcctg ctcccgcatg atgcggctag tgacggtgaa
   452401 ctccgggaat tggagcggga ttcgggcgga ctgaccgcgc gcaatttcct catcccgctc
   452461 cagggcagcg gctccctcca aggccgctgc ccgctcatac gaagtgaacg atacagcaaa
   452521 gggcagggtt atggagttcg gcagccagga cgtccgctac tttctccggg aataccagaa
   452581 ggcgtacccg gaagacgtac tcaccatcga ggaccacatc accgacgacc aggacgcgac
   452641 ggcattcatc tggaggctca accagcaggg caaggcgccg ctcctgcatt tccggaatgt
   452701 cgagggtatc gcctgcgaag tgatcgccaa caccttcggt tcgcgcgagc gtatcgcccg
   452761 tatgttcggg acctcccagg accggttgca cgaagcttac caggcacgct ctcgaaaggc
   452821 tctgccgccg cgtctgctcg acagcggacc ggtgaccgaa tgcgtcgaag aaggcgacat
   452881 cgacctgaac acgctgccga tgctgaagca tttcgcgacc gacagggcga aatacattac
   452941 cagcggcatc atcatcgctg agcatccgga aaccggggcc ggcaatctca gctatcaccg
   453001 cgccatgatc cattcgaaga acgagctggc gacgagcctg cattcgcgcg gccatctgtg
   453061 gcgtctgctc aacatggcaa aggaccgcgg cgagaaactg agggtcgcca tggtcatagg
   453121 cgcacatccc ctcttcatga ttgcggcatc ggcgcgcctt gcattcggtg aagacgagcg
   453181 cgacgtcgcc ggcggcctgc tcggcgagcc gctggaggtc gtacggactc ccagatatgg
   453241 catccgggtt ccagcctatg ccgagatggt ccttgaagga gtgatcgagc ccgaagccca
   453301 ggttgccgaa ggacccttcg gagagtttac cggctactct tccgaccggt cgacaaacaa
   453361 tctcttccgt gtcgaaacgt tcctgcgccg caaggacgca atcctggtca gcgtcgccgg
   453421 cggcaactcg tccgaacatc tcaatctcgg ccgcgttccg cgcgaggcgg agatggtcga
   453481 aaagctgaag cagcgtttcc cgagcgtaac ggcggtccac tatcctgcat ccggcacgca
   453541 ttttcatgct tatatcgccc tcaaccagac aaggcccggc gaggcccgcc agatcatgct
   453601 cggcctgctc ggctgggacg cctatctgaa gaccgtcatt gccgtcgacg ccgacgtcga
   453661 catcacgcag gactccgaag ttctctgggc catgtcggct catttccagc cgcacaggga
   453721 tgtcgtcatc atcgaggggc tgcccggcaa cgcgctcgat ccctcggcaa ccggcatcgg
   453781 cacgacgtcc cgcatgggtc tcgacgcgac acgcgggcct gatttccatg gcgtgctcgc
   453841 caggatcgac gacgccgcct tcggccgcgt ttcttcgatc ctggcgaaac tcgctcgtcc
   453901 atagactgac aacgacgctt ggaggatgca gcgatgaagg cggaccggga acagagaaaa
   453961 cggatcatcg tcggcattag cggcgcctcc ggcgtcatat acggcatccg gctgctggag
   454021 atcctgcgcg atctggacat cgagacccat ctggtgatga gccgcgccgc ccagatcacg
   454081 cttgcgatgg aaacggactt caaggtggcc gaggtcgagg cgcttgcctg tcacgtccac
   454141 tcgaacaagg acatcggcgc ctcctgctcc agcggctctt tccgcaccct cgggatgatc
   454201 gtggcgccct gctcggtcaa gactctttcg gaaatcgcga cgggcatgac atcggggctg
   454261 ctgtcccggg cggctgacgt cacactgaag gaacgccgcc ggctggtgct catgctgcgc
   454321 gaaacgccgc tgcacctcgg ccatattcgt tcgatggccc aggtgactga agcaggagcg
   454381 atcatctgcc cgcccgttcc ggccttctat gcgcgtccgc agacgctgga cgagatggtc
   454441 aatcataccg tggcccgcgt gcttgatctg ttcgacatcg ataccgggct cgcacatcgc
   454501 tggagcgggc ggcgcgctgt cgttctgcca aatcgatttg aagatgccga cgcgaagacg
   454561 aggtgaagca ataccgcttg ttcgccggcc ggaggagggt cggatcaagc ggaaggttcg
   454621 ttgataagaa acgggaggag cgagaatgaa taaggactcg aagtgtgatg ctatcgaaga
   454681 aatgtttccc gcgccgaagc tggcggcgct cgggctgcag catgttctgg tcatgtatgc
   454741 cggtgcgatc gcggttcccc tgatcatcgg cagtgcattg aacctctcga aggatcagat
   454801 tgcgatgctg atcagcgcgg atcttttctg ctgcggtatc gtcacgctca tacaatgtct
   454861 tggcatctgg aacataggcg cccgcctgcc gatcatgatg ggcattggct tcaccgcggt
   454921 ccccccgatt atcgccacgg gcacggatcc ggatcttgga atgccgggcg ttcttggggc
   454981 cgtgattgca tccggcgtgt ttacgcttct ggcggcgccc tatttcagcc gctgggttcg
   455041 cttctttccg gcagtggtca ccgggacggt gatgctggtt atcggcctct cactgatgcg
   455101 cgtcggggta aactgggcgg cgggcggcca gccgatgata aagggtccgg acgggctcat
   455161 tcccaatccg gcttacggcc aaccctttgc tcttgcagtc gccgccatcg tgctggtttc
   455221 cattctcctg atgacccgct tcctgaaggg gtttctcgcc aacctggctg ttctcttcgg
   455281 catagggatc gggttcgcga tagcggtcgc cttcggcaag gtggatttcc aaggcgtggc
   455341 ggatgcgagc tgggtcacgg tcgtgacgcc ctttgcattc ggaatgccgg tattcgacct
   455401 gtgggcatcg gtcgcgctgt gcacggtcat gatcgtcatg atgatcgaag caaccggcca
   455461 gatcctcgcg gtcggcgaca tggctggccg cacgatcacc gaagccgacc tggcacgcgg
   455521 actgcgtacg gacggcatcg gcaatgtcat cggtggaatc ttcaacacct tcacatacac
   455581 cacctatgca cagaatgtgg gattgctcca gataacgggc gtgatgagcc gctgggcggt
   455641 cgcggcaggc ggcatcgtac tgatccttct cggctgcctg ccgaagattg cgttcattac
   455701 cgcttccata ccgagttacg tcgtcggggg cgccgcaatc gtgatgttcg gcatggtctc
   455761 ggcgaccggc gtcaagatcc tctcccgcgt cgatttcgtg gcgaaccgcc gcaacctcta
   455821 cattgtcgcc gtaagcgtag ggctggcgat gattcccgtc gtcgcggaca agatctttgc
   455881 gcagttgccg gagttcatcg accggttctt ccatagcggc gtgctggtcg gaaccttctc
   455941 ggcggtgctg ctcaacctgc tgttcaacgg cattccccgg cgggaagagg tgcagccggt
   456001 tttgctcggt gaaggggccg tccggcatcc ggggtagatc acaggaaaag tattcaacgg
   456061 tttgcccgtg cgaaagcgcg acatgcaccg ccccggcgat atcacctggg gcggtgcgat
   456121 cttatgtagc gttggctggc gggtcggata ccccctgcct ccggcccggt gggatccgcc
   456181 gcgcaaggac aaaggaaatc cgccgaagcc tcccggcttc ggcggatttt tcgtcattcc
   456241 ctcgggatca ataaaccgtt tcgccggccg gggtaaggca gcgcttcaga ccttcctcca
   456301 ggaccgcccg gtcgagattg cggccgatga agaccagctt cgaatagggc atatccttcc
   456361 cccagacatg atccggacgg aaatccatca gcttgtgcac cgcctggagg acgaagaagc
   456421 gagggtctcc ggtgatcgct atgatgcctt tggtacggaa tatgtcgtcg cccttttccc
   456481 gaagcaggtc cgagagatat tccgtcaggc gatgctggtc gaagggccgg tcgaagacga
   456541 aggattccga gctgaccgtc gcatcatgat gatggtggtg gtgatgaccg tggtggtggt
   456601 gatcgagatc gagcagcttg gcgcgttcgg caacatagga tggcgcgaaa ccggaaatgc
   456661 cgaggatgct cgacaggtcc accttgccat agctcgagcg tacgatttcg gccgtctggt
   456721 tgagcttgcg catgtcgcgt tccagaggag cgatctcgcc atccgatacg aggtcgatct
   456781 tattgatgat gatacggtcg gcggcgacga tctgatcgac cgcctggttg tcgcgcccat
   456841 cgagaacggg atcctcgata tgctgtccga tatgcttggc gtcgaccagg gtcacgatgc
   456901 cgtccagcgt cacatgcttg ccgatttcat catcgatgaa gaaggctgtt gcaacggggg
   456961 tcgggtctgc cagcccgctg gtctcgacga ggatgtggtc gaacttgtcc tttcgggcaa
   457021 gcagtttctg caggacctcg atcaggtcgt tgcgcacgtc gacgaagcag cagatgcagc
   457081 cgttcttcat ctggtagatc tcttcctccg aggcgagcac caggtccgag tcgacatcca
   457141 cctcgccgaa ctcgttctcg atcacggcga tgcggtggcc gtgccgttca gtcagtatgt
   457201 ggttcaaaag cgtcgtcttc ccggcaccga gaaagccggt caggatggtg acgggaattt
   457261 tgctgtcctg aagatggttg gtctgcatca ctgcctcgtt tcgttggctt tggtcttgag
   457321 cgcgttcaac acttgctcgg gcgttatcgg gtaatgatgg aagcggacgc cgatggcgtc
   457381 gtagatcgcg ttggcgatgg ccggcccgat cgcgatgatc ggatcctcgc cgacgccttt
   457441 ggcgccgtat gggccgccgg gatccggcgc cgtctcgatg atgatggtgc ggatggacgg
   457501 catgtccatc gacagcggca tcttgtagtc gacgaagctc ggattgagcg agcgcccgtc
   457561 ggtaaggtcg atgacgtagt cctcgctgag cgtgtggccg atgccctgct gaatgccgcc
   457621 ctcgatctgt cctgccgcgg cgatcggatg gatgaccctg ccgatctcgt gtaccggcac
   457681 gacctccaga acggcgacct cgcccgtctc cgtatccacc tcgacttcgg cgaaatgcgc
   457741 ggcgaaggag taggacttcg tcggcatata ggtaccgacg ccgaccagtt gcaccgccgg
   457801 catgccccgc tgcggcccca cggcttcgga aagccggagg ctctggttcg agccgttggc
   457861 gacgaccacg aatccatcgc ggatcgcgag gtcgccgggc tccgccttga gcaggggggc
   457921 ggcgtgctcg agcacctgcc tgcgcacgtc ggccgccgcg agctgcgccg cccggccgcc
   457981 cagataagtc gtgtggctgg caaaggcgcc gatgtcccag ggcaccatgt cggtatcgcc
   458041 ctgaacgacg gagacggcct cgaacggcac tccgagctct tcggcgacga tctgcgacag
   458101 cgccgtatgc gcgccggtgc caaggccagc tgtaccggtg atcagggtca ccgtgccgtc
   458161 ctcgttcatt ttgacgatcg cgttgccctg ctccttgatg ccgggatagg cgctggagcc
   458221 gtgcatttcg cacccgatcc caatcccgcg ccgcttgacg gtttccggct tctcgcgccg
   458281 gcgcagttcg tgccagttcg tctcttccat gacacggcgg atacaatcca ccagcccatg
   458341 gccgacgatc ggatgccccg acggcgccat gtcgccctcg cgcaccgcat tcatcagctt
   458401 gaactcggcc ggatcgaaac cgagcttctc ggccgcctcg tccatcatca ggtcgagtgc
   458461 gtaatatgtc tgcacgacgc catagccgcg aaaggccccg gcgatcggcg agttcgtgta
   458521 gatgcagcgg ccttcgagac gcacattttc gcagcgatag agcgaggtca gtgcagcagt
   458581 gccgacattg gttacgcctg gaccgtgcga tccgtaggcc ccggaattga acgtgaccct
   458641 ggcttcgcgg gcgacgatgc ggccatccct ggtgaagccc tgcttgagcc agatcttgcc
   458701 ggggtgacgc gagcggccgc ccacgaatgt ttccttccgg ctgaactcca tcttgacggg
   458761 gcgcccggtc cggcgtgcaa gcagcgcgca gaggaattcg ttctgaaaca gatcctgctt
   458821 tgcgccgaag cctccgccca tgtggtcgac gatcacgcgc accttgttca gcggcacgcc
   458881 gagcacttcg gcgagggtgc cgcggaccat gaaggcactt tgcgtcgagg tccacatggt
   458941 cagcttgccg ttgccgtccc actggctgac acagacgttc ggctccatat aggccggagt
   459001 cgggcggccg agatcatatt cgcgctcgat aaccagatcc gcttcgccaa agcccttgtc
   459061 gacgtcgccc cgcgtgacga agaccggcgg cagcacgtaa ttctgaccga ggccgttctc
   459121 atgaatcggc ggtgccgcgg gatccgatgc cgcttcgatg gtgaagaggc cgggcagagg
   459181 gtcgtattcg acctcgatga gtgcgaccgc ccgctcggcg atttcctcac tgacggcagc
   459241 gacggcggca acgccctcgc cccagtagcg taccctctcg tccaggatgt actggtcctt
   459301 tgtaaccgat gccgagcgtg gatgcggcga gccggcatgc agcacgcgcg gaacgtcctg
   459361 gtgggtcagc accgccttca ctccttggag cgccagcgcc ttggacgtat cgatgctttt
   459421 gatgcgcgca tgcgcgatgt tgctgcgctt catcttggca tagagcatgc cgggcaaagc
   459481 gacgtctcca gcatatctcg ccgcccccgt caccttttcc agcgtatcgg aacgcttgac
   459541 gcttttgccc acgacggtga aatcccgttc ggacaaatct ctgtcgattc tctcatgcgt
   459601 gttcatagcg ttcccgccct tctcaattcc tccgccgtgg ccctgacggc atcgatgatc
   459661 ttggtgtagc cggtgcagcg gcagatattg ccggcaagcg cgaagcggat ctcgtcctcg
   459721 ctcgggtccg gattttcgtc cagcagcgcc ttggccatca tgatgatgcc cggcgtgcag
   459781 aagccgcact gcgccccgcc gaattccatg aacttctgct gcagggcgtg cggcttgtca
   459841 taggccggct gcaggccctc gatcgtctcg atcgccgccc cctcggcttc ggcggcgagc
   459901 accaggcagg cattgaccgg gcgaccgtcc atgatgaccg tgcaggcacc gcagtcaccg
   459961 acgtcgcagc ctttcttggt tccggtgagg ctgccttcgt tgcgcagcgc gtccagcagc
   460021 gtgcggttca gggcgacgga gagttcgcac ggctcgccgt tgaccgtcat cgaaacaagc
   460081 cggttcattg cacacccccc atggcgtaac cgatggcacg gcgcgtgaga acgccgacca
   460141 tgtcgcggcg gtaggccgca ctcgcccgca cattgcctat gggcgtcgcc tcctgcatgg
   460201 cgctttccgc agcctcggcg agcagcgccg cgtcgatcat gcggcccctg agcaggtcct
   460261 cggtcctgcg cgcgcggatg acggtcggag ccacggcccc gagcgctatc ctaatgtcgg
   460321 aacattgtcc ggcgacatgt tccatgctga cggccacgcc gacggtggcg agttccatcg
   460381 ccttgcggcg gccgtgtttg atataggccc ggccgctcgt cggccgcggc gccggcatgg
   460441 atatgcccgt gacgatgtct ccggggacga gaaccgtccg gcccggaccg gtgaagaact
   460501 catcgagcgg aatgctgcgc tcggtgcctc cactatagac ggaaaggctg gcgccgtcgg
   460561 cgatcagagg tggaatggtg tcggccgagg gcgaagcgcg gcagatatta ccgacaaccg
   460621 tcgcgcgatt gcgcacctgg atcgaaccaa ggagacttac cgccttggcg aggttcggat
   460681 aattgccgtt gaccgccggg gaggtctcga tctcccggac cgtcaccagc gcgccgaagc
   460741 gaagcccgtt tgccggatcg taggcgaaat ccgtaaggcc aggtattttc ttgatgttga
   460801 cgatatggtg cgcgctgcga aggtcctcct tcagctccac gagaagatcg gtgccgccgg
   460861 cgatgatgct tgcgtccttg cccagccgcc tcagaagttc gctggcctcg gcaagggtgg
   460921 ccggctcgta atattcaaac ggtttcatgc atttctcctc ccagatagct gcggtgagcc
   460981 gccgctcgcc gcgaatggct tcaatcgacg acggggcttt catccgcctg tcgtgcattt
   461041 ccgtccggcc cgtcggcggc ctgcgcggaa cgaagctcct gcatggcagc agcccgctcg
   461101 gcgcccagtt cacgttccaa ggcgcgaaga tgctccatgt tgagatgtgc ggccctttct
   461161 ccgtctctgc tggcgattgc ctcgacgatc tccgaatgcg catgattgcc gcagaagcgc
   461221 ggctcggttt ccggccgcga ccaggacagg agcggctggc ggttgatgag atcgcgtatg
   461281 acgcccgtca gcacgtcgtt gccggccatt tccgccagga gcacgtgaaa ccgccgggac
   461341 aggtgccggg catcttccat ccgtcccctt tcataggctt ctcgctcgtc ctccacgaag
   461401 gcgcgcaggc gttccaactc gccttccccg atcgtccctg cgagcttctt aaccgccgct
   461461 gtctcgatca cgatgcgcgc atcgaagatc tgccgggctt catcgggcga gcacatcgcg
   461521 atggatgcgc ccttgttggg gctcagttcg acgaggccgg catgcgcgag gcgcatgagc
   461581 ccgttgcgta tcgccgacct gctggcgccg gaggcaatgg caagctcccg ctcgataagt
   461641 ctggcgccgg gagccacccg atgatccatg atcgcttcga caatgacctg aacgacacga
   461701 tgctcggcct ccggcccgct catcgcggca ccggcagggg cgcggtcttt ctgactcctg
   461761 aaaaagggcg acacggccat aggaactctc tccagtttcg attgtcaaca atctatactt
   461821 ggagcccccg tgtcaacaat acgtactgat tccgaatggt agagttattt tggaacgatg
   461881 aaaatacatg gcatagccct tttctacgac actgcgtaat gaacgaggca atttttcgta
   461941 tctttttcag acatacgagc aactctcgtc gatacatctg ccgacatgac gcgcaaagaa
   462001 ccttgaaaag ggcgtccatt acacatacag atgcgcatca acgtttgcat tacaccgatt
   462061 gtctgtcttg tatactgcac ccatcgcgtg aggagctgac ggaaactgtg ccggccgaac
   462121 attcatgaaa tattcaaatc aatatatatt tattatgaaa ttgcctcatc aatcggcgct
   462181 tcatagtctc catccagacg gaacgagatg gagtcacgcg atgcatacgg ttattggagc
   462241 ccgtcaaggc ggcgcccgcc gcgcacttct cttgcgggga tgccggatcg ccggcgaaat
   462301 tgcggccgag gccgggcgcg acatcctcgt tggagagaat ggccgcatcg caaggatcgg
   462361 ctcccggctg gacgtgggtc cggatgtggc cgtcgtcgag gtccgcggtg cactcatctc
   462421 accgggattt gtcgacgtac atcagcatct ggacaagacc ggcgttctca ggttcacgcc
   462481 gaatccctcg ggaacattgc agggcgcgcg ggaggcattc gccgaatatg cccgcaaggc
   462541 gccggaagag gatgttacgc gacgggctgc gcggaccatg gcgcgctgcc ttggccgggg
   462601 caccacggcg atccggagcc atataaatgt cgacaaggat gccggcttca acgggatcaa
   462661 cgccctggcc cggctgcgct ctgaatgggc cgaccggctc acgctgcaga tagtcgcatt
   462721 catgacgccg catcccaacc aggatctcgc ctggctggag agcaacatcg atgccgccgt
   462781 tgaacaggcg gacgcggtgg gaggcacacc ggccgtcgcc gaggacccga tccgctatct
   462841 cgacattctg tttgcagccg ccaagcggca tggccggccc atcgacctgc acctcgacga
   462901 acacctgaac cccgaacggc cgcttttcga tgcggtgttc gaacgcgtcc gcaaattcgg
   462961 cctgcaggga cggaccgtcc tcgggcacgc ctccgtcctg agtgcacttc cgaggacgga
   463021 attcgagcgc atccgcgacc gcatgatcga cctcgacatc gcggtcgtga ccttgcctgc
   463081 cgccaacctc tatttgcagg gccgaagcca cgacatgtta ccgccccgag gcttgacgcg
   463141 cgtcgccgag ctgatccgct cgggcgtggc aatcgcaacc gcgtcggaca acattcagga
   463201 tccgttcgtg ccgacgggat cgggcgacat gctcgagatc gcgcgctgga cgctgctcgc
   463261 cggtcatctg cgcggcgacg agctcgccac agcctatgac atgatcacca agattccggc
   463321 acgcatgatg aatttgggcg ctgactacgg cattcgcgag ggcgcctggg cggatctcgt
   463381 catcagcgat tgcgaggatg tgagcgcgct cgtcagcgca ggtccggact gcatgcaggt
   463441 ccttgcaaaa ggccggccga tcgcagcacc cgcattccct gccatggcag ccatatgcgc
   463501 attggaaaat gtcccctgaa cggcaacaag ccgtcgggac gggcatgatg aggagaggaa
   463561 gggaggagca tcatgatgat taccagaaga ggctgtttgg catcggcggt cgcagcggcc
   463621 gcactcattg ccgcggggtc ggcactcgcc gagggtgcac cgttcaagat gggattgctt
   463681 gtccccggaa gcgtctcgga ggaggggtgg aacaggatcg ggttcaacgc cctcaaaggc
   463741 gtggaggctg aactcggtgc cgaggtgagc tatgtcgagc ttcagcagaa ccccgcatcc
   463801 ttcgagaaag ccttccacga cttcgccagc cagggctaca acgtcattct cgggcacggc
   463861 ttcgagtttc aggacgccgc actcgcggtt gcgcctgaat atcccgatac ggtctttctc
   463921 atttcctcga gctacatatc cgagggcaat gtcatcgggc tcaacacgga tacgagccaa
   463981 cccttctatc tgatgggtgt gatcgcggcc aagacgggca agaaggcggg tctcgtcgga
   464041 ggcatggaga ttccaccgat caaggaggcc ttcgaaggat ttaccaatgg cgtgcgaagc
   464101 gtcgcgccgg actttccgat cagcgaagtc tacatcggca atttcaccga tgcgacagcg
   464161 accaaggaag cgagcctcag cctgatctcg caaggggcgg actttgtcct gccgaacgcg
   464221 tcaggagcga cggttggcgg attccaggcc gccgcggaat cgggcgaaaa cgtcaagacc
   464281 ttcagcatct tcagcgactt cacatcggtt gctcccaaga acatcctcgg cctttacatc
   464341 gccgattatg cccgtggggt catccggatc gtcggggaca taaagaatgg caaaaagccg
   464401 acgaccaatg tcgaattcgg tctgaaagat gccgacgtca tgcaattcac ctataacgac
   464461 caggctgcaa atccggtgac ggagaacgtt cgaaaatacg tcgatgaggt gaaggccaag
   464521 atcgcagccg gagaaatcaa gacccggcag aaataacgcc gaatccattc cggtgcgaaa
   464581 aggatggtca ggacccggcg aaccgcgccg ggtccgccgg caccccggga tgctcccatc
   464641 ctgccacgat aaccgcttcg atcgattgtt cgacggaagg ccttgggcct ttccctaatc
   464701 cgaaggcagc aaactcatgg caaacagtga aagtggacag ccgctagcgg ttgcccccca
   464761 agcctatggc gccctgtggc gaggcttgct ccgtcccttg cgtaccgtcg ctcagccggc
   464821 tgcggccgtc gcgctggctc tggcctgcgg tgcggcgctt ctggccttca atggttacga
   464881 cgcgcgcgcc gtgatcgacg tgatggtgct gggagtcttc caggacaccc gctcgatcgc
   464941 tgagattctt ctgaaggcaa cgccgctgat cctgatcggc gtcggcctgt gcgttgcctt
   465001 ccggtgcagc atctggaaca tcggtgccga ggggcaattc tatgccgggg ccgcggccgc
   465061 gactgcgata ggcgtctcgt tcaatggatt gggtgcctgg ctctatgtgc cactggtcat
   465121 gcttgccggg gctcttgccg gggcggcatg ggcggccatc gcaggccttt tgaagatcta
   465181 tttccgggcg agcgagatcg tgacgacgat catgctgaat tacatcgccc tcatcatgac
   465241 gagctatctc gtgaccgggc ccctgcggga cgcggctgca gcttatccgc aatctgcgcg
   465301 tctcgtacag gaggcatgga tgccgcgcat ccttccgccg acccgcctcc acatcggaat
   465361 cctcgttgcg ctggtgcttg cggtcgtaat gtatgtcttt ctgtttcgca gtgcccgggg
   465421 ctacgcattg agggtggtcg ggatcagccc ggatgccgcg cgttacgccg gaataagcgt
   465481 ccccaggaac atcatgatct cgatttgcct cagcggcagc atggccgggc tggcaggtgc
   465541 cttcgagatc gcgggcgtca cccggcggct cttccagtcg atctcccccg gctacggctt
   465601 cgaaggcatt gccgtcgcac ttcttgccaa caacaatccg atcggggcca tcttttcggg
   465661 gctccttttc gcggtcctgc gaagcgggtc cgagcttatg cagatcacgg ctcagatacc
   465721 ccaggttctg gtgctcgtga tccagggcat cgtcattctc tcggtcgtgg gctttgccgt
   465781 gttgcggatc ccgtcattgc gcccttccga ataggtggaa ccatggaaga tctagcaagc
   465841 ctgagctttc tcgcggcaac cattgcagcc tcatggcggc tggcggcgcc attgatattc
   465901 gcatccatcg gcgaagtgtt ttccgaacgc gcaggagtcc tcaatatcgg cctcgaaggc
   465961 acgatgctgg cgggcgcctt tgccggcttc gccgccgcct tcaccagcgg gagcatcctg
   466021 ttcggggtcg ccgcggcaat cgcggcaggt gttctcgtcg gactgctgtt tgcgttcttc
   466081 accatcacga tcaaggcgga ccagatcgtg gtcggcgcgg ccatcaacct gctgggcctc
   466141 ggcctgacgg cgttcctgtt tcgctcctat tttccctccg cgggcaaagg tatcgacatt
   466201 gccaaacccg tccacctgcc ctggctcagc gatctgccgt tcttcggcga agcgcttttc
   466261 cggcagaacg cctttgtcta cagcacgctt cccgtcgccg cgcttgcggt gttcgttctc
   466321 tacaggacgt cgttcgggct gacgcttcgc gccgttggcg agcatccgaa ggccgtcgac
   466381 gttgctggcc gcagcgttgc gctctaccgc tacggcgcgg tgctcatctg ctcggcgctc
   466441 gcggcactcg gtggagcctt tctgacgctc gctcactcca accagttcgt cgaaggcatt
   466501 tcctccgggc gcggcttcat agcccttgcc gtggtcgttt tcgcgagatg gtcacccatc
   466561 ggcgcctttg tcgtgtcgct gctgttcggg gtcttctatg cgctgcaact gcagctgcag
   466621 gcgcaaccgg tgcatttcct tccctaccag ctgttccagg ccctgcccta cctcatgacc
   466681 attgcggcgc tgatctttgt ccgaaatcgc gtgggcacac cgagcatgct cggcgtcgct
   466741 tacaaaaaga gctgaggagg cgaaaatgtc gggaaggcag ctgcttctaa tggatggcat
   466801 tcacaagcgt ttcgggccgc tcatcgtaag cgccggcgtc accctcgata tcgaggagaa
   466861 cgaaattcac gcccttctcg gtgaaaacgg tgccggcaag accgttttga tgagcatact
   466921 ctgcggcgtt ctctcgcccg atgaagggca gatcattttc aagggccagg cactcaagcc
   466981 cggctccccg cgccaagcca tcaagcatcg catcggcatg gtccaccagc acttcatgct
   467041 ggtccccaac ctgacggtcg ccgagaacta cgttctggga cagggctcgc cgttcagcgt
   467101 gatccgcgac atgaagaccg ttcatgcccg catcgtcgag ctcagcgacc gctacggtct
   467161 cggcgtgaag cccgacgcgc tcatctccga cctttcggtg ggcgaacagc agcgcgtcga
   467221 aattctcaag gtgctctacc acggcgttga actgctgatc ctcgacgagc cgacggcggt
   467281 cctgacgcct caggagaccg atcggctcct gcatttgctt cgccgcctcg tcgaggacgg
   467341 gaagacggtc atcttcattt cgcacaaact ggacgaggtg atacgcgtca gcgaccgcgt
   467401 cagcgtgatg cgcgacgcca aggttgtccg caccgtgaaa acctccgaaa ccaatgcgcg
   467461 cgaactcgcg cgcatgatgg tcggcagaga cgttctgatg gatttgccgc gggcaccgat
   467521 cgagcccggt cgcgtcgtgc tctcggtcga gcatctgaac tgcgacggtg aatccgggct
   467581 tccggcactc cacggggtgt ccttccaggt ccgggccaac gaaatcgtcg gaatcgcggg
   467641 cgtctccggc aatggccaga gtgagctggc tctggccttg acggggctcc ttccgattgc
   467701 ttcgggcagc gtcacgctcg aaggggccga actcgtgggc cgatcgtccc acgacatcaa
   467761 tcagatgccc attgcgcata tccccgaaga tcgtcaccgg atgggtatcg tgctgccgct
   467821 tccgctgacg gaaaacgtga tacttcagcg cttcgacaag ccgccgttca gctctcgagg
   467881 catgctcgac atgagcgaaa tcacgaggca aacccgtgat ctcatgcggc gcttccaggt
   467941 caaggcctcc ggcccgggcg accgcatcca gaatctgtcc ggcggcaacc agcaaaagct
   468001 cgtcgtcgga cgcgagctgg accgccgctt cgatttcctg ctgatcaacc agcttacgcg
   468061 cggaatcgac atcggcgcga ccgagctggt gatgcacaag atcctcgagc aacgcagcgc
   468121 cggcaaggcc attctgctga tatccacgga gcttgaagag ctgtttacgc tctgcgatcg
   468181 aattctcgtc atgtatgagg gccgtctcgt cggtgaaatg ccacccgatc gcggccgcct
   468241 ggaggagatc ggactgctga tggccggcaa atcgccgatg tcggcggcgt gagcgaacgg
   468301 ccgaaggcga tcgacagccc atccattgtt tttgaagccg aaaaagagga acttggaggt
   468361 gaaacggtaa cggacggctt tgtgaccgcc aagcgcgaag tacgaaacgc agagaactac
   468421 gtatgaatgt gacacttcgc cagttgcagg catttattgc cgtggccgaa ctcgggcgtt
   468481 tccatctggc ggcggatcac ctcggactta cgcaatcggc gatcagcatt ctgatcagag
   468541 atctggaagc cgtcctcaag caccgcttat tcgaccggca cacgcgcatg gtcagcctta
   468601 cgacggccgg agcggagttt ctgccgcagg cccgcaagat catgtcggac ctcgagatcg
   468661 cagtcacgaa cgtccacgag ctggcgaacc tgcagcgcgg ccgggttacc attgcggctg
   468721 cgatcgtgct cgctgcgacc ttgctgcctc cggtcatcgc gcggttcgtc aagcgatatc
   468781 ccgacataca ggtgcaggta cgggacatgc cggaggagga gatccggtcg gcgttgaaac
   468841 gaaacgaggc ggacctgggc atcggcaccg tttccgccga cgacccggag attcaggcca
   468901 gcgtgctcat gcgtgaccaa ctcacactga tttgccgctc cgaccatcgc ttcgcaaggg
   468961 cgccgcaggt gagctgggcg aatcttgccg gcgaggctct gatcggtctt gcaaaggaca
   469021 accccttgcg cggactcgtc gatcacgcgc tgatcgcctc cggagtcgag gtgaagacga
   469081 gatacgaggt gcggttctca acgacggcga tcagcatggt ggcggaaggc cttggcatag
   469141 cgatccttcc ggaaaactca cgtcaactca ccacgaatgt ggacgtgcgg atcgtcgacc
   469201 tcgtcgatcc cgtcatcagc cgcaacatct ccattctgca gtaccggcaa ccgatgctct
   469261 cgccggcggc ggcgaagatg aaggagtttc ttatgggagc gagccgcaag ccctcgtgac
   469321 agcatcatga tggcccgtcc gaggccccca gcaaggcgag ggcctcatcg atcgccggca
   469381 tggcgagacc ggctcctcgc cgggcgaccg ccagcgcgcc gaaggcatta gcaagacggc
   469441 agcattcccg tcccgtcatt ccggtgaggc ggccatggat gtgcccggcg gcgaaggcgt
   469501 cgccggctcc cgtggtatcg aaagcatcgg cggggagcca ggaggcgctc tccgtcaccc
   469561 ctgcgctaca gagcaacgac cgaccctcat tcgcctttac cgcaacgcgt tcgacgccga
   469621 gatcgagcag ggcgcgaact gcctcttcca ggcttgtgcc gtacggcttg tcggccagcg
   469681 gagctaggtc cgcatcgccg agcacgatcg tgtcaagcct cggcaggatg gtccgtacgc
   469741 gcgatgcaag cctcgaaacg atgccgcccg gaatatcgag ggtgatcgga atgttgcggg
   469801 cgacggccag gccgattgca tgatcggcag cctccgattg ggggctctgc aggaaggcgt
   469861 agccggacag gtggaagagt tcggctgcat cgaacgccgc cgcgtcgatt gcggccggcg
   469921 aaagctgtgc attggcgccg cgataggcga acatggttcg ctcgccggtg ctgccgacgg
   469981 tcacgacatt gatctgggtc ggttctgccg aatcccgacc gatccaagtg gtgtctatac
   470041 cctcgcctcg cagatcccga agggcctgtt tgccccagcc gtcatcaccg accctgccga
   470101 taagcctgca tcggtgcccc gacctcgaaa gggcaaccgc cgtattcgtc gcagaaccgc
   470161 ccagaaacat cctctgggcg gtcgcgatcg cctctccgcc ttcgggcgga taagtggaga
   470221 tctcaagggc cagatcgacg ttgatgtcac caagcaggac gatgacggac atgtcgcaac
   470281 cttagatctc catatgcatc tggtctatcg cactatccac atcggcgatg atgtcgtcga
   470341 tatgctcgat gccgaccgaa aagcgcacga gaccgtcgac gacgcccatc gcctcccttt
   470401 cctggctcgg aatatccagg aaggccatgg tggcgggcac ctgcgtcgtc gttctgagcc
   470461 ccccgaggct cgcggcgaag gaacaaagct gcaaacgctt tagaagccgg acaccggacg
   470521 cttcgtcatc aacctggaac gagagcattg cgccgccgcc gcgcaactgc tccttggcgg
   470581 atgcgtagtt cgggtgcgaa ggcaggcccg gatagaacac gcgcctgacc ctcggatggg
   470641 cctcgagatg cttcgcgagc gccagcgcat ttgcgcattg cttctccagc cgcagcgcca
   470701 gggtctgcgc gccgcgcaaa agcagccatg cattgaaggg cgaaagcggg gcgcccagtt
   470761 tgttgagcgt gttccaacgc acgtcttcga gccagtccgg cggcaggata tcggatttca
   470821 acgtgataac cccgcccacc gcgtcattat gcccgccgat gaacttggtc gcgctctcta
   470881 cgaccacgtc gacgccgaaa tcatgcgggc ggcagactgc cggcgacgcg aaggtattgt
   470941 cgcagatcac cacgatgccg cgcgcatgtg ccagctccac gagcgccttc aggggcggca
   471001 ccttcatcgt cggattggca atggcctcga cgtagagcac cttcgtttct tccgtaagcg
   471061 cgttctcgac cgccctcacg tcggtgcaat ccaccaggct caccttcagt ccgaaatcct
   471121 gggcgcggtg atcgaagaat tcgtgtgtgc tcgaataggt cgtcagatcg gcgacgatgt
   471181 gatcgcccgc cttgaggatg ccgaacaagg catgcgagat ggccgccatt ccggacgcgg
   471241 tcgccaggca ggccgtgccg ccggtgagct tggcgatgtg ttcttcgaac ttgtattccg
   471301 tcggattgcc gcagcgtgaa tagatgttca cttccttgcg cgcgccggca acgatctgat
   471361 cgtagatgtc tccgtcatac tggaaattcg ccgacatgta gatcggatag ctgatcgact
   471421 gggaatgttc ttccggcgtg tagaatacgg cttggcttgc aaaatcgagc tctttggggg
   471481 acatcgcgac tctcctggga attggcagcg gcaccggttc ggtgactcac cccttgacgg
   471541 ctccgccgat aagggccgcc gttatctggc gttcgaaaaa gacgaatagg acgagcggcg
   471601 cgatggctgc gatcaggatc gcggccagca tcaccgggta attggttata tgttcgccta
   471661 cgaaatcggt cagacccacg ggcaaggtct tgcgtgacgg gctgttgatg aagaccacag
   471721 ggaacaggaa atcgttccag acccagatca tgttgacgat ggcaacagtg aacattgccg
   471781 ggcgggcgat gggcagcgcc acccgcagaa agatcttcca ctccgaggct ccgtccatcc
   471841 gcgcggcatc gaacaggtcg cgcgggagcg tgttgaagaa tgcctgcatg atgaagatcg
   471901 agacgggaac gttgaaggcg gcggtcggca ggatgacgcc gagatgcgtg tcgaggaggc
   471961 ccgcgccgcg aagcatgacg accagcggga ccaatgcgac ataggccgga atcgccattg
   472021 cggccgtcat gctcaactcg accgccggta tccagcgcgg ccgataggct gcgagcgcaa
   472081 atccggcgag cgtcgcaagg accaccgtga tcagggttgc ccccgccatg atcagcaacg
   472141 aattgacggc ataaccgccg agcgcgccgc cgctccaggc gccaacatag gcatcgaggg
   472201 agaagctctt cggcagcgac cagacggagc gcatgaactc cctgttggtc ttgaaggtgc
   472261 tgtagatcat ccagaagaac ggaaagatca ccatcaggac gtgcgcggtc aacactgcca
   472321 aaacaatggt acttgtcagg ttccagcggc ggacggccgt catgaccagg ctcccgcacc
   472381 cgcaccaatc cgcttcatat aacggaaagc gatccatgct ccgagagccg taagcaccat
   472441 ttgggcgaag ccgatggccg cggcgtaccc catttcgaag cttccgaagc ccatcttgta
   472501 aagataggtc gacaccacct cgcttgcgtg gttgggaccg ccgttcgtca gaacgaagac
   472561 gagagaaaag gtcttgagcg agccgatgat cgccagcagc gaattggcgc gcacggcatc
   472621 ccacaccatg ggaacggtga tcgaaaagaa cttgcggaag tcgccggcac cgtcgatttc
   472681 cgccgcctca tagacacttt ccggaacgtt gcgcacggcg gccacgaaca ggagcacgta
   472741 aagaccgaga taggtgaagc tcatcacgac gacgacggcc gtgaatgccg tctcggattc
   472801 tccgagccaa ccgcgcttga ggccaccgag gccgatcccc gagagccccg cgttcaccag
   472861 gccgaaatag ggattgtaca tgaagcgcca gagcagcccg atgcatattt cgctgaccat
   472921 gaccggcacg agatagaaga agaggaaaat acggctgaag gcgggcacga tgcggaccag
   472981 gcaataggcg atcgcgaggg ccagaaacac ctgcagcaca atcgccgata gcgctacgag
   473041 gatgttgcgg aaaagcgcct gccagaagat cgcatcgccg gcgagacgga cgaaattgcc
   473101 cgcgcccagg aacaccggca tcgatgcgcc atcccatcga aagagcgaaa gccatcctgc
   473161 ataggccacg ggataggcga cgaaggcgaa gacgaagagc agcgcgggcg acaggaagag
   473221 aatggcagcc cggttggatc tctttgcgaa gctggtatcg gcgctcatgc tcttccctcg
   473281 aggggccggg gcgttacttc gcccgcaatg cgtcttcgat gcgcttggcc gcatccgcgg
   473341 gcggcagcga gccatcgagc actccttgca gcgaggtgta atagatgttc gtcgctgcgg
   473401 gcggcatggc ggtgtcgtag aaaggatcga ggtggccggc agccttcatc agcttgttgc
   473461 tgatatcgta gaggactggc ccggcggccg tttcggtggt ggcgtccttg acggtcacca
   473521 tcgtcttgcg caactcgaca tatttggtca tcacctcgcg cgaggtcagg aacttcagca
   473581 gggtgaccgc gtctgcctta ttctccgcct tctgcgaaac gccgaaactc gcagcgacgc
   473641 cggccagcac gtcggactgg tccccggccc cgcctgcgac agcggggaag gcgaaatagc
   473701 caagctcgaa gccttcgggc gcgtccgccg atgcgcctat ctgccacgtg ccgttcagca
   473761 tcattgcagc ctgaccgttg aggaagagca tattggcttc ctgatcgctc atgccgttga
   473821 atccgatcgg gaaatactct tgcttcgcga gttcggcgag cttctccatc gccttcgtcg
   473881 cctcggcgcc cagcgtcgca tccggatccc cgttcacgaa agccgagacg acgcccgagc
   473941 ccttgagccg catttcgaga tactggaacc agaacgttgc cggccaggaa tccttgttgc
   474001 cgagcgaaaa ggggacaagc ccttcacctt tcaccttctc ggcgagggcg agcagctctt
   474061 cataggtctt cggcaccgtc cagccgttct cggcgaaacg ggccttgtcg taccagaaca
   474121 ccaccgaatc cacgtctacg gggacggcat aggtgtgacc gtccttgctg gtctgggaga
   474181 ttgcgctttc aaggaaactg tcacgccacc cgtccctggc gagttcctcg tccagggcat
   474241 acatctgccc gcctttgacg aaggcgttca ggaagccgcc aggcagcgtg tagaagacat
   474301 ccggaggatt gcccgaggcc atggcggtgt tgagcttcgt cttgtaggcc gattgctcgg
   474361 cagcgaccac ttcgagcttg acctcgggat gggcctttgc gaattcgccg agagcgaagt
   474421 cgatgaattc gaccttgtcc tgctgacccg cataagcgtg ccagaacgaa agctctccgg
   474481 cggaagccgg cattgctgcc agagcggcag cggcgccggc gatcagaaga cgtttcagcc
   474541 tcacgatgtc ctccccattt ccctgcggcc aagcactgcc gcccatgaag tgatgccaca
   474601 tcgaaaatca cgtgtctata gtgacaccac aacatcgcca tgctaatacc ggtcttagga
   474661 cagccccagc tagcaggagc cgccatgact gttgacttgc gtggtccctc cgtaccagcc
   474721 agcagccggc tgcgcagcgt tttgcctaaa ttgtcggacg ccgaacggcg ggtggcgcta
   474781 tggatgctga agaacgtcga cctgagcatt cggcagtcca tgtcggcgat cgcccaggcg
   474841 acggatgtca gcgacacgac cgtcttgagg atgtgccgca ccgccggctt cgaaggtttc
   474901 accgacctga aactggcttt ggcgcaagaa cctcgcgaag caatcgaaca tagctcggga
   474961 gaaccggagg cgagcgccct gcaggcagcg ggccggctgt ttcgcgcgat aactcaggcg
   475021 ctcaacgaca cattcggggt gctcgacgag gcgaccttcg caaaagcgct ggatctggtc
   475081 gccaatgcga aacacataat ggtcgggggc gtcggtggtt cgggtatcgt cgcccaggca
   475141 ttctaccagc gatgtatccg gctcggcctg cgctgcgacg cgccgatcga ttcacaattg
   475201 cagatcatgc atgccgcact caccggcccg ggggatctgg tggtcgctat ctcctattcc
   475261 gggatcacga gcgatccggt cctcgtgctt caggaagcaa aagcccgggg cgcttccacg
   475321 ctctgtatta ccggcaacag cagttccgcg ctggcgcgcc tggcggatgt cgtgcttgtc
   475381 agcgtttccc atgaacaagg cagcgaaccc atggcggcgc aaatcgccca gatgaccctg
   475441 gtcgacgcgc tttacgcggc gctcgtcgcg cgaaatcccg agccggccca actcaccgag
   475501 gaacgcatgg tcaacgcaat ccttcccaag tcaatctagt tgcaaacgga aactgccttg
   475561 aaaattcaga tctatacgat gcagaccgcc gccgaagcgg ttgccgcagc cgcagccggc
   475621 gtggactatc tcggtgtcac gccatcgaac cgcggacttc ccggcgagat caccttcgcc
   475681 aaggcacgcg agatcgtcga cgcgctcgaa gggaaagccc agcgcgtcgc tctatcggtg
   475741 gaaagcaatc tcgatgacat cgccgcgatg gtcgaggcgg ttcgtcccga tgtcctgcac
   475801 ctttgcggcg acatcgcgct tgtgacgccc gaacaggtca aagtgttgcg gtctcgactg
   475861 tccgctgaac accccgcctt gcggatcctg caggccattc ccatgaccgg tcccgaagct
   475921 ctcgatcaag ccgccgcatt cgagcccttc gtcgacatgt tcatcctcga ctcggttgcc
   475981 ccgcatatag gcggcatcgg tgctgccggg gtgacgcatg actggtcgct cagccgcgaa
   476041 atcgtcgcca gaagcaggct cccggtcatt cttgcgggtg gcctcaggcc cgacaatgtt
   476101 cgggcagcca tcgaagccgt ccgtccgtgg ggggtcgatt ccctcaccca cacgaaccgg
   476161 ccgctccccg aaggtggctt tcgcaaggat ctggacaaga tcgcagcttt cgtggaggcc
   476221 gcgagagcga cctgaaaccg ggggcgtccc ccgcccggcc gatgtcgccg cactccaggc
   476281 gaaagcctgg agtgcggcct ggaagggctc cgggtagaga gcgtgcatct ccgacgccac
   476341 gcgtgccgat gcacttcgat cgccttttgc tcttgaagcg cctgctgcgg cgactagatc
   476401 atagttgttg tccgcccgga ggggccgaca cttcatgact cgtccccagg caaggagctt
   476461 cgttcatgaa cgatcgctca gatcgcacca cttttcgagc gcgtcccgcc aaagctctac
   476521 ggcgggacgg agcgtgtcgt tcaccatttg acggaagagc tcgtccggca gggtcacgag
   476581 gtcaccctct tcgcgagcgg cgactcgatg acatcggcaa ggctcgtccc ctgctcgcaa
   476641 atggcgctga ggttgaaccc cgccattcag gatccgattc cctatcacat gatgctgctg
   476701 gaagaagtgc gccggcaggc gcccgccttc gacatcctgc acttccacat cgatcttctt
   476761 cattttcccc ttgtccgcga cctcgccgga aagacggtga cgaccctgca cggccggctc
   476821 gatctgcccg acctccagcc gttctacgcc gcgtttccgg atgtccccct ggtttctatc
   476881 tcgcacgatc agcggcggcc gatgccgccg gtcaactgga tcgccactgt ccatcacggg
   476941 ctggctccgg acgtccttcc cttcaccagc cctcccaagg gcgactacct ggcctttctt
   477001 ggccgtatct cgccggaaaa gcggcccgac cgtgcgatcg aaatcgccgc ccgggccggc
   477061 atgccgttga aaatggccgc gaaggtggac cgggtggacg agccctattg gctgagtgag
   477121 atcgagccgc tcatccggcg ctatccgaat gtcgagttca tcggcgaaat caacgaacat
   477181 cagaaggccg aattccttgg aaacgcgcgc gccctcctct tcccgatcga ctggcccgaa
   477241 cccttcggtc tggtgatgat cgaggcgatg gcctgcggca cgccggtgat cgcctttcgc
   477301 tgcggctcgg tgcctgagat cgtcgaccac ggcgtttcgg gtttcatcgt cgacagcacc
   477361 gaggaagcgt tgaaggcggt ccacggactc gaccgggtcg atcgccgtat ggtccgtgcc
   477421 acattcgaca ggcgttttac ggcccagcgc atggcaaacg attatctcga tatctatcgt
   477481 gctctggcaa gcggcagcca aagggtcatg ccgatccatg ctgcgaacga aagcaatgcc
   477541 ggccctggct ctgcccgggt cgcctgatac cggatcacat tgaacgcgca acgacgaagt
   477601 tcagtgtgat cgatcgaagg agcgagagcg ggatgcgcgg cggaaagccg cgcgaaaggc
   477661 tcctcatccc gcgctgatgc aacggagacc gatcctatgg gaaccaatct ctccggagcg
   477721 gcggccgaag ccgctcccga tgtgacatct gcggacgaac tggggccggc agcggtctcg
   477781 cgttacgagc gaagctccag atccctgaaa cacggcgata ccttcgccgt gttcgaccat
   477841 aacggcgacg cgttttcctc tccttccaat ccggagggca tcttccatcg cgatacccgc
   477901 catctctctc aattcgtgct gaggctgaac ggcgccagat cgctgctgct gagttccacg
   477961 ctccgcgacg acaatgccac gctcgactgc gatctcacca atccggctct cgtgctcgat
   478021 accggtggcg aggttttgaa gcatgacctc attcatgtgc ggcgcacccg ctttctctgg
   478081 caggaggcct gctacgaacg actggtgctg cgcaacttcg atgaggcccc gagaaggctg
   478141 caggtcgagc tgtcctttgc cgccgacttc gccgacctct tcgaagtgcg cggcacccca
   478201 aggcggcggc gcggcaccca tcataacgcg ctcgtcggca atggccgggt ggtccttgcc
   478261 tatgacggcc tcgacggcca gacccgcagc acgactcttc gcttcgatcc ggagccgcag
   478321 aggcttacag ggcaggaggc aagctttgtc gtcgagctcg ctccgaacca ggcgcaatcg
   478381 atcttcatcg agatcgtttg caacagcctt gaggacaatc cgcacccccc ggccttcaac
   478441 ttctttctcg cgctgcgcga cgcccgcagg gcgctacgct actccgcctc gcgcgcggcc
   478501 gcggtcgtga cctccaatgc ggtgttcaac gaggccgtca gacgcagcgt cgccgatctc
   478561 tatatgctgc ttacggagac gcccgagggt ccctacccct atgccggcat tccctggttc
   478621 agcaccgtct tcggccggga tgcgctcatc accgcgcttg agaccctgtg gctggacccg
   478681 gcgatcgcga agggcgtgct cagacatctc gcagcaaacc aggcgaccga tttcgaccca
   478741 gttgccgatg cggagccggg caagatcctg catgagatgc gttatggcga aatggcggaa
   478801 ctcggcgaag ttcctttccg gcgctattat ggcagcgtcg attccacccc tctcttcatc
   478861 atgcttgccg gcgcctatct cgaccgtacc ggtgataccg acaccgtgcg gggcctctgg
   478921 ccgaatatag tggccgcact cgactggatc gatcgtttcg gcgaccgcga cggcgacggc
   478981 ttcgtcgaat atggaagccg gacggcgaag ggcctggtga accagtgctg gaaggacagc
   479041 catgattcga tcttccacgc cgatggcaga ctggctaaag ggccggtcgc gaccgccgag
   479101 gtgcaggcat atatcttcgg agcctggcgg gcggccgccc gcctgtcgcg caagctcggc
   479161 catgcagagg atgcgctgag gctcgagcaa cgggccgaag acctgcgcat ccgtttcgac
   479221 gcggccttct tcgacgagga gcttggcacc tattcgctgg cactcgacgg ggacaagaac
   479281 ccctgccgcg tccgttcctc caatgcgggg catgcgctct tcaccggcat cgcactgcct
   479341 gagcgcgccg gcagggtcgt gtccacgctg atggcccagt cctccttctg cggctggggc
   479401 gtgcgcacga tcgccgcttc tgaggcgcgc tacaatccca tgagctacca caatggctcg
   479461 gtctggccgc atgacaatgc tctgatcgcc gcaggcttcg tacgctacgg cttccaggca
   479521 gaagcggcca gcatcttcga agggctgttc gccgcctcca cctatatcga cctcaggcgc
   479581 ttgccggagc tcttctgcgg cttttcgcgc cagcgcgccc gcggccctac cttctacccg
   479641 gtttcctgcg tgccgcaggc ctgggcggca gcggcacccc tttatctgct tcagtcgatg
   479701 atcggcctcg gcttcgacgc cgagaagtcg caggtcatgt tgaccgaacc caccctcccg
   479761 cccttcctcg atgaagtcgt gctgaaacgg ctgcgggtcg ggcctgggat cgtcgacatt
   479821 gcactgaggc gatcgcgatc ccaggtggtc gtggacgtgc tggagcggaa gggcggcgtg
   479881 aaggtactga cgacccattg agccctggta caccggaata ccggatacgc cgtttctcaa
   479941 cgtggcacta atgcattagt gtattgctcc tccattcccg ccatgctaca gccgcatgga
   480001 agatccactt gtcgggaatc gtacagtcaa tgacatccac acttcgaagc gcgcggtggt
   480061 ttgcgcccga tgaccttcgc tcttccggtc accgctcccg ccttatgcag atgggctatg
   480121 atgccaggga ttggggcgag aagccgatca tcgcgatcct gaacacgtgg tcggatctca
   480181 atccgtgcca cgcccatttc aagcaccgga tcgaagatgt gaagcgcggc gtgctgcagg
   480241 ccggcggatt tcccgtcgaa ctgccggtgc agtcgctctc ggaaagctcg ctaaagccta
   480301 cgacgatgct ttaccggaac ttcctggcca tggaggccga ggagttgttg cgcggtcacc
   480361 ccatcgacgg gacggtgctg atgggcggat gcgacaagac cacgcccgcc ctcgtcatgg
   480421 gcgccatcag tgccggcctc ccgatgatct tcctgcccgc cggcccgatg ctgcgtggcc
   480481 actataaggg cgaacatctc ggctccggat cggatgcgtg gaaatactgg gacgagcgcc
   480541 gcgcgggaac gatcacggat gaacaatgga tcggcgtgga ggaaggcatc gcccgctcat
   480601 acggtcactg catgacgttc ggaacggcca gtacgatgac ggctatcgcc gagtctctcg
   480661 gactgacgct tccgggcgcg agctcgatcc ccgcggccga cgccaaccac atccgcatga
   480721 gcacgcgatg cggcaggcgt attgtcgaga tggttcacga gaagctggcg cctgataaaa
   480781 tcatcaccga aaagtcggtc gcaaatgcga gtgccgtggc gatggctacg ggctgttcga
   480841 ccaatgccgt ggtgcatctc atcgcaatgg cgcgacgggc cggggtgccg ctgacgctcg
   480901 aagatctcga caggatcagc cgcacgacgc ccgtcatcgc caatatcaga ccctccggca
   480961 aacagtatct aatggaggat ttctactacg ccggcggcct tcgcgcgctg atggcagaga
   481021 tgaaggagct cctgcatctc gatgcgatga ccgtgagcgg atttcctttg ggtgcaacgc
   481081 ttgaaggggc ggaggtccat aattccgatg tcatccggcc gctttcgaat cctatctatc
   481141 atgaaggctc gcttgccgtt ctgaagggca acctggctcc ggacggctgc gtcgtgaagc
   481201 cctccgcctg cgaggagcgg ctgcgggtcc atgagggacc ggcgctcgtg ttcgacagct
   481261 atccggagat gaaggctgcg atcgacgatg aggatctcga cgtcacgccc gaccacgtgc
   481321 tcatcctcag aaatgcggga cccaagggcg ggcccggaat gccggaatgg ggtatgctgc
   481381 cgatcccgaa gaagattctg aaacagggct gtcgcgacat gctccgcatt tccgacgccc
   481441 gcatgagcgg cacgagctac ggcgcgtgca tcctgcacgt ggcgcctgag tctcatatcg
   481501 gggggcctct ttcgctcgtc aggacgggag acgtcatccg tgtcgacgtg ccgaaccgga
   481561 cgatcgatat gctggtcgac gaggagactt tggcgaaacg ccgcgccgaa tggaaacctc
   481621 ccgccgaccg ttacgaacgt ggctatggct ggatgttctc caggcacatc aagcaggcca
   481681 atgaaggttg cgacttcgac tttctcgaaa ccgccttcgg ctcagcggtg ggcgagcccg
   481741 acattttctg acttcaagag cgtcccacgg aggaaaacat gtccgtttat agtctgtcca
   481801 aagaggcccg caggaaattc gaaggcgtaa gctgcgccac tttgtgcacc gccctcttca
   481861 agcggggcct gcgcaaccag ttcatccagg acgttcgtcc ggtctcgccg aaggccacga
   481921 acatggtcgg ccaggccttc acactcagat acattcctgc tcgcgaggac ctgaaccagc
   481981 tttccgtgtt tcagaacccc gaccaccccc agcgcgcagc cgtggagcag tgccctcccg
   482041 gcttcgtcat ggtgatggac agccgcaagg acccgcgagc ggcttccgcg ggctcgatcc
   482101 tggtttcccg actgatggtg cgcggagtgg cgggcgtggt caccgatggt ggtttccggg
   482161 acagcccgga aattggcgag ctcgacatcc cggcctatca ctgccgccca tccgcgccga
   482221 cgaacctgac attgcaccag gcgctcgaca tcaacatccc gatcggctgc ggcgacgtcg
   482281 ccgtctggcc aggagacgtc gtcataggcg atcgcgaagg cgtggtcgtc gtccccgcgc
   482341 atctggccga agagatcgcc gacgaagccg tcgagatgac ggccttcgag gacttcgtca
   482401 ccgaagaagt cctgaagggg cgctccatca tcggcctgta ccctgcgacg caggaacgga
   482461 caaaggccga ttttgcagcc tggcggcaga gcaaggggcg ctaggcatgg cgatgctccg
   482521 ggacgtgacc gttcttcaag ccgccgaact tccggaaaaa accgaccgcg agttgaggga
   482581 aatcttcaac gtcctccggc ttccaacgga cgaggcggcg atcggcccgc tcctggccga
   482641 gcatgggacg cgcattcgcg gcgtcgccgt caggcacgct catatcgacg cggcaatgct
   482701 cgaccggctg ccggcgctgg agatcatctc cagctacagc gccggtctcg acggcatcga
   482761 tgtcgagagt gcgcatgccc gcggcgtcgt cgtccgcaac acgtcgagaa tcctcgccga
   482821 ggatgtcgcc gatctggcgc ttgcgttgag catctcggcc acgcgcggcc tcatgcgcgg
   482881 ccacgacttc gtgcgcgaag gcagatgggg acagatcgcc ttccctctgg gccgctcgct
   482941 tcgatcgatg aagacgggga tcatcggact tggacatatc ggctcggccg tcgccgcccg
   483001 cctgcgggcc atcggcgcgg cgaccgccta ttccggaccg cgacgcaagc cggtcgacct
   483061 tccctatttc gacagtgtcg aaggcctggc ggcctgggct gatcttctgg tcgtcacctg
   483121 tcccgcgggc cccgagacga tcgggctcgt caatcacgcc gtcctcgcga acctcggccc
   483181 ggaaggctac ctggtgaacg tctcgcgcgg cacgatcgtc gacgagcagg cgctcataag
   483241 cgcgctcgcc ggaaacagga tcgcaggcgc agcgctcgac gtcttcgaga acgagccctt
   483301 cgtcccggat accctccgca acgacccgcg cgtcgtgctg tcgccgcata tgggcagcgg
   483361 aacacacgag acgcggcaac agatgggcga cagcatggtt gccgccctgg tggagcattt
   483421 cgagagccga agcgcgtgat catcgcaaga agccacgcgc aatcttcgcg gctttctgag
   483481 gggtaggcaa ggcgacaagg gcggcggatt ataactctgg caagaggcgt ttggcccttg
   483541 cagggctgta cgcgcgccgc ccgcagctct acttcgtgcc ccttccctct cggtgaaaga
   483601 gaagtgtgat cgctccgagg atgatcgctc cgccgatcac cacatcgagc cggatcggct
   483661 cgccgaagaa caggaggccg atgacgaggg cgagcggcag ccgtatgaaa tcgacggtaa
   483721 ccagcaggga tgcatccgcc agcttcattg cccgtgcgaa ggaaagctgc gcgaaaagac
   483781 cgccgatacc ctgcagcgtc atcaggaaaa ggctgaacag cgaaggcgtc tgccaaaagg
   483841 gcaaagcgag gaggaaggcg acgggaaccg tcaccaggag attcagccag gctatgctga
   483901 ccgggtcctc gcgcccggcc gaaaccttca tcaggagcgc gacgatggca agaccgaccg
   483961 cggaagcgag tgcccaggca gcgcctgtgt cgaaggtttc cgcacccggc cggacgacga
   484021 tcaggatgcc cgcgaagccg ccggcgaggc tgagggcccg gccggaggaa aaccgctcgc
   484081 ccagaaaaag caccgagccg aaggcgacga aaagaggcat ggtgaaggcg atcgcagtcg
   484141 cggaggccag agggatctgc gtgaccgcga tgaaggccgc gagcagggcc agaagcttga
   484201 tgatggccct gatcgcatgg acgtggaacg acatcgtccg ctctacgacg aaaccccgcg
   484261 agcgaatgag cagatagagc gcgcccagac tggcgagatt gcggaagaag acgatcccga
   484321 tcgggtgaac ctctccagcc acgaagcgca cgatcacgct atccatcgcc gcaaccagag
   484381 aattcgcccc catcaacagg gctcctgcga cgaccgcagg catggcgatc ttcttcatgc
   484441 cgcgtcggcg gctgtctgcc acttcggctt cggcgtcgca ttgatgagct ggcgcgtata
   484501 ggcatgctgc ggactgcgga agatctcttc cgtcgtcgca tgctcgacga tctcgccgct
   484561 cttcatgacg atgatccggt cggcgaagtg acgcacgatc ggcaggtcat gggttatgaa
   484621 aatgtaggcg aggcccagcc ggtcgcgcaa ttccgccaag aggccgatca cctgcacctg
   484681 caccgagacg tcgagcgccg acacggcctc gtcgcacacg acgagctccg gatcgcaggc
   484741 aagcgcccgg gcaatggcga tgcgctgccg ctgcccccct gagaactgat gaggatagcg
   484801 tgcggcatgc tcggggttca ggccgacgag ccccagcaat tcagtaacgc ggtcgcgcca
   484861 acggggcttc tccagaatat ccttgtggat gcgccacggc tccgaaacga tatcgagcac
   484921 cgtcatgcgc gggttcatcg agctgtaggg atcctgaaaa accatctgca ccttccggcg
   484981 gaaggccagc aattccttgc ggtccatctt caggatatcg cgcccgtgga acagcgcctc
   485041 tccgccggac gcttcgttga gacccagaag cacgcgcgcg acggtggact tgccggagcc
   485101 gctctcgcca actatgccga tggtctcccc tgccgcaacg tcgaagctca acttcttgac
   485161 cgcgtgcaac cgcgccggtt tcgcgaaaaa cccggaggag agagtgtaga acttgtcgat
   485221 gttccttact tccaggatcg gctttccagc gggccttccg cgtttcggcg gggcttcgtg
   485281 atcgccatgc ggtagcgcgt tgatcagcgt ccgcgtatag gtatgggcgg ggttttcgaa
   485341 gaccgcacgg gcctcgccct cttccacgat gcggccggat ttcatgacga tcaccctgtc
   485401 ggccatgttc gcggccacct cgaggtcgtg ggtgatcatg atgatggcaa ggccgtcctc
   485461 cgcctgcagc ttcttcagaa gctcgagaat ctgggcctgc acgctcacgt cgagcgctgt
   485521 cgtcggctcg tcggcgatca ggatttccgg cctgagcgcg attgccatgc cgatcatgat
   485581 gcgctggcgc tggccgccgg agaattggtg cggatactgg tcgatgcgct tctccggctc
   485641 cgggatgccg acgcgcctca atatatcgat cgccctctgc cgcgccacgc caccgctcgc
   485701 cactccgtgg acgctgaaca cctcctccat ctgccagccg atcgtataga ccgggttcag
   485761 atgcgaaagc gggtcctgga agatcatcgc gatcttgcgg ccgttgaggt cccgccgctc
   485821 accttccgaa agcgaggaga gatcgcggcc gcgataggcg accgaccccg cgcagatgtc
   485881 gccgggaggc gtgtcgatga gtcccatgat cgcactggcg cttaccgatt tgccggaacc
   485941 ggactcgccc aggatcacga gcgtctctcc ggcatcgaca tggaagctga cgccgtttgt
   486001 cgcgcggaag gatccgccaa gcgacaggaa atcgacggtc aggtccttga cctcgagaag
   486061 atgtgtgccg gtcatttgcg tttctccgga atgcccttct tcgagcgagc gagttcgatc
   486121 cgccagcgct gctgcggatc ggcataggtg cgccaccagc tcgagagaat attgagcgaa
   486181 agcgtcgtca gcaggatcgc aagacccggc cagaatgcaa tccaccaggc ggtcgagaga
   486241 tagccacggc cggtggcgac catggcgccc caggtgaatt caggcgcctg gatgccgagg
   486301 ccgaggaagc tcagcgatga ctcggcaaga acgacggtcg cgaagtcgat cgcgccgatc
   486361 gtcacaaggg tgggcagcac catcggggcg atatggcgga aaaggatgcg cctatgattg
   486421 gcgccaagcg caacggcggc gctcacgaac atacgctctc tcacctcgag cacttccgca
   486481 cgagtcgtgc gcagataaat cggcacgcgg gtgatcgcca ggacgaggac gagattggtg
   486541 acggaaggcc ccaggctgaa aagaacgatg agggcgagca ggagcgacgg aaagctcatc
   486601 acgatatccg caccgcgcat gatcatcgtg ccggcggcgc ctcgcgaata gccggcaatc
   486661 aaaccgagca taccgccgat cacgaccgaa aaaagcacgg cgcagaacgc gatgccgatg
   486721 gtgttttgcg cgccgaccac aagccgagcg agcaggctgc ggccgagcgt atcggcaccg
   486781 agaacatagg tccagccctg ggacaggtcg aacggcgcca tgtttcgtgc acggaaattg
   486841 ggcttgtcga taagatcgcc cacaagccat ggaccgaaaa cggcacatcc gaccacgatc
   486901 agcaggaaga tcaccgcggc gagcgccagc cagtcccggc tgatgaggcg cagcacctga
   486961 aaacgagaga ctttcgtctc gggggtatcg gcagaagtcg tcatggctgt cgcgctcatc
   487021 tcgtttcaaa ccttatgcgg ggatcgagcc gcgcatagac gagatcgatc gcgatgttca
   487081 ggacgaagat ggcgatcgcc gtaaccagca ccgtcgcctg gatgagcgcg aaatcgcgcc
   487141 tcacgatcgc gtcgatcatg agtttaccga tgccgggcca gccgaagatg gtctcaacga
   487201 ccacggcgcc gttgacgagg cttgcagcaa ggtcgccggc gacggtgatc accgggagca
   487261 gcgaattgcg cagcgcgtgg cggaagacga tacgggatcg gttcacgccc ttggcacgcg
   487321 ccgtcttcac ataaggggaa gcgagtgcgc tcatcatcgt gccgcgaacg acctggacga
   487381 ggagaccgaa gggccgcaat gtcagaacga agatcggcat gatccagtgc agggccgtcc
   487441 ccgtgcccga ggtcggaagc aggcctagcc cgaccgagaa gacaaggatc gcgacgatag
   487501 cgacccagaa atccggagcg ctggcgccgg caagcgacgc ggtggtcgcg agcttgtcga
   487561 agaggctacc cgggcgagcg gcggcaagcg atccgaccac gaccgcaaga cagagcgaaa
   487621 gaacaatcgc gatcgcggcg agcttcagcg tttgcggaaa ggcctcgagc gcgacctcca
   487681 tggccggccg gttgcggctc aacgcgtcgc cgaaatcgaa acgcgccaga tcgacgaggt
   487741 agcggccgaa ttgaacgacc aagggatcgt taaaaccgtg cgcctccgaa aacgcctgac
   487801 gctgcgcttc ggacgaatcg agcggcagat agagataggc cggatcgccc gtcagcctcg
   487861 aaaggaagaa gaccaggacc agaagtccga tcactgcgat cacgctctgg ccggcgcgtc
   487921 tgagaatgaa agcgaacacg gcgtttcctt tccaccgcaa acagggacgg cgccgcgacg
   487981 tgggacacgc cgcggcgaaa ggtcgggttc gtcagtcctt gaagtgaatc tcggagagcg
   488041 cgatctcgct gttcgttttg agatccggct tccagtcgag gcgcgagccg acgcggacat
   488101 atccgatcat gtggtacatc ggcacgtctg caacgatctc gtcgtgcacc tttgcgaaga
   488161 cctcctggaa gagcttttcg cgctcgtcgc cggtcgcagc catggctttc ttgaggacgg
   488221 catcgagatc cttgtctgcg atcgtcgaat attgcccctc gctcagatac atgaccggcg
   488281 cggtgaaccc ggcatcgccg gtattgttgt cgtgctgctg ctggaacagg gtcgggccgc
   488341 gcccttcggg aaaaggcttg tcgagatagc gtacccagtc tgccgcctcg agctggcgta
   488401 tcgaaacgtt gagcccgatt tcctgccaca tggaccggat cgcttccagg ctttcagccg
   488461 aattcgggaa aaagccgttg cgcccgatca gcacgatctc cttgtcgacc ggagcgccgt
   488521 cggccttggc ctgctcgacc agcttcatcg cctcttcggg attgtaggtc catggcttga
   488581 tatcgggatt gtgtccgcgc acgcccggaa cgaccatttg cgacgccctg agcacatcct
   488641 tgccgaacag cgcttcgccc atcccgtccc agtcgatggc catgttcagg gccttgcgga
   488701 tacgaacgtc gtcgagcggt gggatttgcg catcgatccg catgcgtgtc gtctcggaat
   488761 tcagataggc gaagtccgac tctgcattgg tcgcgtcctg taccgcgatg gacggagtca
   488821 tatccgcttc accggattcg accatggccg cgcggatagc cgactcgctg cgccagacat
   488881 aggttgcacg cgtgacgtcc ggcttggcac cccagtaggc atcgtgacgc ttcagcacga
   488941 tctgttcatt ggacttgctt tcgaccacat aggggcccgt gccgacggga tcgttgcttt
   489001 ccttgtcgaa gggcatgttc ggcgagacga tctggacggt gccgagcagt gtcggcatga
   489061 tcggcaccgg gctgtcggag gaaatctcca ccgtctgcgc gtcgaccgcc ttcggcgtca
   489121 gcttgacgtc gccgaatttg gagcggctgt cgcaggtgat gttcggattc atcaggcgat
   489181 tgatggactt gaccaccgct tcggcattga actccacgcc atcctggaac ttgacgccgc
   489241 tcttgagatg cacgcgccag gtaagatcgt ccacctgctc ccatttttcc gcgagccagg
   489301 ggccaacggt gcctttctcc gtatcgatga cggtcagggt ctcggtgatg ttggaattga
   489361 tgatgcggcc gatatccgac cggatggagc gacagggatc gagattggcc ggctgctccg
   489421 gcaatacgat cttcacttcc ccttcggctg cgatggcggc gccagcgagc agcgtcgctg
   489481 caaatagcgc caaggcgccg gtacaatagc ggatgatcat ttctctctcc tcctcgatgg
   489541 tcttccagac gcctttgcgc ggcgaccgtt cacacggcct tattgctcct ccgcaccgca
   489601 ttcacattaa agcactaatg tattagttag catacatcaa tctgtcaact cacgctaagg
   489661 cgcttaccga cggcttcccc gcgcgcctca ggcaatcggc ctcggcaacc tgcaaggcct
   489721 tcaccgcgac gccgaccgga ccaagttttt cagcattaag attggagatc atcggcatca
   489781 gcggccccgt atctgcaata cctgccagcc gcatcccatc atggaggacc tgaaggcccc
   489841 cgagctccgc gcgaactttc tcgaactcca ggaacggccg gctgagttca aaggcttctg
   489901 cgccgcgtcc tgccttgtag agccttagaa gttccatcgc cgccgacggg gcaatgcaga
   489961 cggcccccga ggtataggtc gtcaggctgc ggccgccgag gtgatcgtga attggcgttt
   490021 cgcccatgcc gctcgccatc cgatcttttc caatcgccgc gatgatggcg tcgagatagg
   490081 catcctgtgc aggatcgggg cgctccaccg catatttgac gaagtcgacc gcgccttccg
   490141 agacgagccg gccaagctcg tccggatcga cgtagttctc ccgcttaaga tataatacga
   490201 ggccatggcc caggaccgcc gcaaggcggc gtacgccatt ggcgacaccg gccggatccg
   490261 ccggaaactg cgtgggcagg agcatcacat tcctcaaacc cagatcgcgg gcgatcggcg
   490321 cctgcgccag ggcttttccg aagtccggac cgatcgacgt tatgatacgg gtttcgggcg
   490381 aagcggcagc gatcaccgcc tgcattcccg cccgatagtc ctccagaccg aagtggtaga
   490441 gattggcatt tccgccatag agtaggatac ccactccgcc ttcctctatg tggcggatga
   490501 tcgcggcgtt ggcgtcggcg ttcaccgtaa ggtccgcgtt caacgcgatg ggcggaaccg
   490561 caaccaccga agctgcgtaa tcacgggcat caagtctgat ttgcatgaga acctcctcca
   490621 taagtcggtt ttcattacaa catcgtcttg gatttgtaaa atataattac ttatcaggag
   490681 tcgattgttc cgtccgtcat ccgtcggcgc gctttgatga tatgcgtctc catcgccaca
   490741 cgcgcccatg cggcatcttt cgtgcggatc gcttcgacaa tctcggcatg ttcggcgatg
   490801 acccggcggg cgcgtgcctg cgagccggaa cgggtgagcg ccagcgagac attcatgaaa
   490861 ctcgtcagcg agacctccgg cccctccagc gccttggcga agaattcgtt tccggttgct
   490921 tcgcagatcg caagatggaa acgcctgtcg ctttcaggca ggaaagcccc tctgccgacc
   490981 tcatgggcga aggtttcatg ggcttcgacg atggcggcaa gctgcttttc cgtgcgccgc
   491041 tccgcagcca gtgcggccgc ctggccttcc acatggaagc ggagctcctg atatcgaagg
   491101 aagcgcgaga tatcctccag gtcggcgagt tccggaagag tttgcgaagg ccggctgagg
   491161 acataggtgc cgctgccgcg ccgcgcttca acaaggccgt cgactctcag acgcgccagt
   491221 gcttcccgga cgaccggccg cgaaacgccg aaacgttcgg ccaactcgtt ctcggtcggc
   491281 agccgcgcgc ccggttgaaa aactccattc aatatgtcgt gcaggatgcg cccatagacc
   491341 tgatcggcat agctcgaagg gcgggcttcc gctaggcttt cgagaatgag cggcttctcg
   491401 ggcacggcga tccttcctat cctgccgggg ccgccgtcgc ggtcccttca cactgacaca
   491461 ttaatgcatt attacaggat cgggaactgt tctggaggaa tggatttttg atatcggaag
   491521 ctccgacagc caaacatcga accggccttg atcgcacccg gcagattgca ccgcaaattg
   491581 tcgaatatct tcgcgagaag atcctcgcgc tggaacttgc tcccggtacg gcgctctcac
   491641 gcgtcgaact gcagaaccag ttcgggctca gccagacgcc ggtgcgtgac gcgctcatgc
   491701 ggctggagga agaaggtctc gtcaccgtct atccgcaata tgcgacgctg gtctccaaaa
   491761 tcgacatcaa cctggcgcgt cagacccatc tcatgcggcg cgccgtcgag caggaagccg
   491821 tcttcaacct tgcggaaaac gcaaacagac ggcagatcgc tgatcgcctg cgaaccgcga
   491881 acacgaacct gaaggcgctg gcctcgaagg agtttgccga ttttctcgcc gccgaccgtg
   491941 cattccactt tataatattc gaagaagccg ggctggagca tatctggccg atcatccgcc
   492001 gccacagcgg ccatatcgat cgcctgcggc gcctcaatct cgtcaatgtc ggcaccaaac
   492061 gggtcgtgga tacccatgac atgatcatcg aaggaatcga aaagggcgcg cccgtggacg
   492121 cggctcaagc gatgaagacc catctctccg gcacattgtc gatgatcgac gacatcgcgg
   492181 cgcgttatcc ggattatata gaactggggt aagaagcccg ggagccgggc ggagcaacga
   492241 acggccggat ctcttctcgc agccgtgttt cagatgccag ccggatttct ccggccggca
   492301 tcttgcaggt caggcgaggt gatggcgttc ctggagacca tagacgggtg tcgatatgcc
   492361 ctcgcagcgc gctttcaact gcagcgacag atattgcgaa taatgccgcg actgatgcag
   492421 gtttccgccg tggaaccaga gcgcctcctg ctgcgtcggc ttccacatgt ttcgctgctc
   492481 gccctcccag gggcccgggt ccttcggcgt atcggagccg aggccccaga ccttgccgac
   492541 cttgtccgcg acttccctgg agatgaggtc ggctgcccag ccattcatcg agccgtagcc
   492601 tgtagcatag acgacgagat cggccggaag cactgtgccg tccttgagca ccacggaatc
   492661 ctccgtcaga tggctgacgt cagaaccgga tttcagcttg atgctgccgt cgatcacgag
   492721 atcgcaggcg ccgacgtcga tatagtagcc ggatccgcga cgcagatact tcatgaaaag
   492781 gccggatccg tccgcgcccc agtcgagcat gaagccggcc ttttcgagat cggcatagaa
   492841 cttggcgtcc cgctcgcgca tcttctcgta tagcgggatc tggaactcgt gcatgatccg
   492901 gtagggcagc gaagcaaaga tcagatcagc cttgcgcgtc gtcatgccgg cggcaagcgc
   492961 ccgctcggaa taaaggtctc caagcccgat ctccatcagc gtatccgacc gcacgatgtg
   493021 cgtcgacgat cgctgcacca tcgtcacatc cgcgccccct tcccagagcg cggcgcagat
   493081 atcgtgcgcg gaattgttgg agccgatgac gacgaccctc ttctcacgat atgcatcggg
   493141 accgggatgc tgagaggaat gctgctgctc gcccttgaag atatcctggc ccctcagctt
   493201 cgggacgttc ggcttgcccg acatgccggt cgccagaacg agctgcttcg gccggaggac
   493261 gacctcctcc ccatcgcgct cgacgacgac cgtccattcc ttcgttacat cgtcataccg
   493321 tgctgatttg caggtggtcg aactccagta attgagttcc atcactttgg tatacatctc
   493381 cagccagtcg ccgatcttgt ctttcggggc gaataccggc cagttctccg ggaaggggat
   493441 ataggggaga tggtcgtacc agaccggatc gtgcaggcag agcgacttgt agcgcttccg
   493501 ccagctgtcg ccgggccgct cgttcttctc gataatgatg gccggaacgc cgagctgcct
   493561 gaggcgcgcg ccgagtgcta ttccgccctg acctccgccg atgatgacga cgtagggttg
   493621 gcttgtataa ccgagttcgg ccgcttcggt ttcgcgcttt tccttccatg tcttgcggct
   493681 cgggtcatgg ccgtgctcgg cgccgagcgg acgtctggct ccccttggct cctcgtgtcc
   493741 tttaagctcc gtcatcgtcg tcagaagcgt ccagatcagg ccgttcttga ggcggatatg
   493801 gccgtggccg cgcgccacct ccgtttcgaa ttcgaaccat ccttcggtga caccgtctgc
   493861 gtcaccaggc cgttccatct cgtcctggcg cagccgcgcc ggcttgatcg cggcaagctg
   493921 gctcgtcagc atatcgcgga tctggtcctg cccctccatg gttttgagat tccaggtgaa
   493981 ggcaaccaga tcgcgccagt agcaatcggc ctggaacagg ttgacggcgg catcgatgtc
   494041 gccacgttcg agggctcttc cgagtttggc gagcacaatg tcgatgcggg tgccgggact
   494101 ttcttcaagc atgggtatcc tcctcttcgc ttggttgacg cgcgggcggc tcctcgactg
   494161 cccgcaccgg atctacgcgt tcagttcgtg aggtcgatca ggatcttcag gtgcctgcca
   494221 cccggatcga gaagcgcatc gaagccgtcc gccacggccc gatcgagacc aatacgaccg
   494281 gtgacgacct gttttgcggg caaatgtcct gaggctatca agcggatcac acgcggccag
   494341 tagtgtgtcg ggtaggccca ggagccgcgc agatcgatgt ccttgaacgt gacctgaaac
   494401 cagtcgatcg ggttctcgtg cggatgcagc ccggtctgaa ccacgacacc ctgcttgcgc
   494461 acggcgtcga cgcagccctt gagcgcgtgc tcgtttccga cgcattcgat agcgacgtcg
   494521 cacccgactt tgccctccgt agccgcgcgc accacatcgc ccgggttgct ccgacccgga
   494581 ttgatcgggg ttatgtccgg aagaatggat gaagcgaatt caaggcgggc gtcgttgatg
   494641 tcggagacga agagctgcgc agcaccggcc gcgcgtgcgg caagaagggt caggactccg
   494701 atcggcccgg caccggtcac gagcacgctg ctgcccgccg tgaccccgcc ccggtcgcaa
   494761 gcgtagacgg cgaccgcgct cggctcgaca agcgccgcct cctcgtcgct catctcttcg
   494821 ggaatcttct cgacattgta ttcgttgaga agggcgtatt ccgccatgcc tccccacgcc
   494881 cagctcagac cggcaagggc cagatcggta ctcaggtgga agaggccgcg atcggcgaag
   494941 aagtcgccgg cgcgcggcat gatcagcggc tgcacggata cccggtcgcc ggcacggacc
   495001 gaagtcacac cctcaccgac ggcctccacc acaccgccga actcgtggcc aaggacctgt
   495061 gggccatggg cgccggtaaa cggatgtggt tcctttggaa cgaaaatcgg accgtaggca
   495121 tattcgtgca ggtccgttcc gcagattccg acgaagcggt tgcggaccag cacctgcccc
   495181 gctgcgggtt cgcccggcgc ctgaatgtcc tcgatcctga gatcccttgc cgcatgaaat
   495241 ctgagcgctc gcatgtttcc tcccgatgac tgtggtgtcc gggcagcgag ttgcaatggc
   495301 cgtgccaatt gcctggagat gaggaaatgc aatgtaatca atgccggcga tgactggcct
   495361 tgttgcagtc agtggttcga gcgccacagc tgtggcacct gacctgttgc gcgggcgcaa
   495421 ccgtgctcag cgcttgaggc tgtagcgctt gatctgccgg tgcaccgtcg agcgatcgag
   495481 ccccagccgg cgggcggtct cggaaatatt ccagtcgcaa gtggcgagca taaggctcaa
   495541 ggccgccccc gcctcgcttc cgccgacggt gtccgcattc accaggaggt ggtccggcag
   495601 gtcgccgatc tccacgacgc cgttctcggc gagcgctgca gccacggcga cgacattgtc
   495661 gagttcgcgg atgtttcccg gccaatcatg cgccttgagc gccgcgagcg cggcctccga
   495721 caatatcaac tcaccgtcgc cgtgccgctt cagcagctgt tcgagtatcc agtcaaagtc
   495781 cggccggtcc ctgagcgccg gaatcgagag ggtcgcggca ttgagccggt aatagagatc
   495841 ctcgcggaac gccccttgcg cgacaagcgt ctgcagtggc cggtgcgatg ccgacacgac
   495901 ccggatccgg acctttcgcg gcacggtgcc gccgaccggc aggacctcgc cctcggcaag
   495961 tacgcgcaac agcctgcttt gcagggcaag cggcatgtcg cctatctcgt ctaggaagag
   496021 cgttcctccg tccgcctgct cgatcaggcc cttgcgcccc ttcgccgaag cgccggtaaa
   496081 ggcgcccggc aggtagccga aaagctcgct ctcgatcaat tgctcgggga tcgccgcgca
   496141 gttgatcgcg acgaactgcc ccttcagacc gctgccctcg tggatagcgc gcgcaagatg
   496201 ctctttgccg gtccccgtct ctccctgaac gaggatcggc agcccggtac gcgcgagctt
   496261 cgcggccctt gcctgcagcg cggcgatcac cggcgcgtcg ccgccgagcc gccgcaaggc
   496321 cggcggaatc tgctcgcgcg agacgactgg cgcacgtacg gtcgaatgcg gctcgatcgc
   496381 atgggcgaag agcgcatttc cgtcgcgggc gaagacgagg cgctcctggg tcgggcggcg
   496441 ccgggtgagg tcggaaagat cgtcgacctc gatatcgaag aaacgtgaca ccggctcgcc
   496501 gatcagtttc cggggatcgc gccagtccag cccggtcgag cgtgcgagta ttttggctcc
   496561 cccatgcgtc attccggcga tccggccgag gccgtcgatc gagatggccg cctccggatc
   496621 gacatcgaga aattcgggtg agcgcgagaa ccgcagcacc cactggtttc gcgcctgcgc
   496681 catgaggttg gcaagctcta tgcgtctcac ggtggcggtc accagatgca gcgcgaggtt
   496741 ctggctggcc ttgaggatcg gcgaactcag cagcgagata tccagcaccg cggagagttc
   496801 gcccttgttg tcataaatcg gtgccgccgt gcaggagagc ggggtgtggg tattgtcgaa
   496861 atggtcggtc tgatggatcg tcagcgcctc tcccgtttcc aggcatgcgc cgaccgcaca
   496921 ggtaccggcg cgccattcgg accactccga gccgagataa agcccggcct ttcgcaagct
   496981 gttgttgaag agagggtctc caaggaactc cacggtcacg ccttcccggt cggagagaag
   497041 cagcacgtag ttctgcccgg caacctggcg gaacaggtgc tccagccccg agcgagcgat
   497101 gccgatcagg tcctccgatt gctgccggtg ttccttgagc cgggtttcag gcacgatata
   497161 ggcttcgcaa ctctgggccg ggtcgagccg gtgatgctcg aggcagcgca tccaggattt
   497221 cacgaccgtt tcgtcgcggc tgaccggaag gccacggcca acgcgctcaa tttcgcggat
   497281 atgttcggaa tgtgaaaaca cgaccgcctc ccaacggaca cctcgctcct cgcctgaagt
   497341 gtgcgcatgg cgaggccgaa tgtaaaggaa ccggccgttt ttgggctcgg gttacctcat
   497401 tcgggagctt gtcacaggga caatggacga aatcgacgca ttcgggcgct cgctcatcag
   497461 ctacgccgtt tcagttgcgc gcgcggcccc ctccagcagc cggtccacga tcatccggcc
   497521 gatcggaatc gcagacgttg cagccggaga tggcgcgttg cagacgtgaa gcatccgttc
   497581 ggtctcttcg aagaggaaat catggacgag gctgccgtcg gccgtgacag cctgcgcgcg
   497641 gatgccagat tgtgcacggc taaggtcggc gatcgttagc gacggacagt atttccggca
   497701 ctcctgcaga tagcggtatc gagaggcaga gttggcaaat tcacggattg ccgaacgcca
   497761 gttcctggct gccattttcc agaagccggg gaaagccgcc atgtccgcca catcggcaag
   497821 agcgaagctg cccttcggat aaccttcgcg cgcaaagccg agcacggcat tgggcccgac
   497881 cgtcatccct ccttcgatcg tccgggtgag atgaatgccg aggaagggca ggcccgggtc
   497941 tggaatggga tagatgaggc gccgggtcag agccgccttg gacgacggaa gcacataata
   498001 ttccccccgg aacggaacga tccggtggtg gatcgtcagg ccagccatca gagctatacg
   498061 gtcggactgg aggcctgcgc aggcgatcag cttgcgcgcg tcgaagcggc cggaggcact
   498121 tgcaaccctc acactgcctg cctcctccac gatggcggag acctcggccc cgcgcctgat
   498181 ttcgccgccc cgggcttcga tacgcgctgc cattgcccgg cagaccgccg aatagtcgac
   498241 aatcccggtc gcatggacga ggagcgcacc gaggccggcg atattcggct cgtcggatcg
   498301 caattgcgac atcgacaggc ggctgtattc gatgccgttc cggcgcgccc tatcctcgag
   498361 gctctccatt ccttcaatct cggcatcgtt cgtcgccacc agcagtttgc cgcaggtttc
   498421 gaaaggaata ccgttttcgg tgcagaacgc ctttgtcgcc tccgctccct cgcggcacag
   498481 cgtcgctttc agggatcccg gcgcataata aatcccggca tggatcacgc cgctgttatg
   498541 gcccgtctga tgacgcgcaa gctccggctc cttttccaag agcaagatcc tggagccggg
   498601 cactctgtcc tgcagcgcca tggccgtcga caggccgacg atgccgcctc ctatgatgca
   498661 atagtcgtac aatccgcaac cctctcgacc gccgaaggca ggcggccgtc gctctcttgt
   498721 ctagacgatc tcaccgcttc gttgaagtac gctgcatgac agtagcggca agggtccagg
   498781 cggccgacgc gggccggtca gaaggcgcgc acacgcggca gaaccgatct gccaaagaca
   498841 tcgatgaact caagctgatt gcgaccgaca ttgtgaagat atatctcgtc gaagccggcg
   498901 gcgatatcct cctcgatcca ggcggcgtgc cgccccggat ccgaggagat cctgacatgc
   498961 ttgtcgagat cctcgggacg aacgctcttc gtggctgact cgatttcacc cggcgtcctc
   499021 agcgtctccg actgaccggg gctgagcacg ttgctcctcc actgatcgaa agcattttgc
   499081 cgcgcctcct cgtccgtctg tgcataggag acatggacct gaaggcagag aggcttgccg
   499141 tcgccgccgc cgcgcctgaa ggcctcggca atggcggcaa gctttgtcga cgactgattg
   499201 acggtgatga gaccgtccgc ccattctccg gccgtttcgg ccgtttcagg cgttagagcc
   499261 gcggcgatca gcgccggcgg gtgctcggcg agcgtataaa ggcgggcctc cgacacggca
   499321 atgggtgctt gccggttaac cgtccggccg gcccaaagct cgcggatgac ctcgaccgcc
   499381 tcgaggagtc tggcccttcg ctccgccttt tcgggccaga ccccaccgac agcctgttcg
   499441 ttcagcgcct ccccactgcc caacgccagc caggcaagcc gccgcgggaa catctgcgca
   499501 agggttgcag ctgcctgcgc cgttatcgcg gggtgatagc gccagccgca aggaaccgtg
   499561 acgaggccga agctcttctc tgtcgcctgt agggcggcgc cgagccacgc ccaggcaaag
   499621 ccgctttgcc cctgccgctc gctccagggc gcgagatggt cggacgacat ggtgcaatcg
   499681 aagccggcct cttccgccgc ccgcgcccag cccaacaggt cgagcggcgt aaattgctcg
   499741 tgcgatgcgt gatagccgat cctcgccatt tcagtccttc cttcccgaat ggagccaggc
   499801 atagccgaat gggccaagac ccatcgtcag atgctggccg gagagctcga cctcgccttc
   499861 gccgaaaaca tccttgagcc tggcgtcgat ggcgccgggc agttcgactt ccgcccgccg
   499921 cttggcctcc gttagattat gcagcacgac gaacagctcg gtgccgtcgg aataggcgag
   499981 cgcaaacagc gcgggatccc gtgtatgcag cacgatcggc cggccccttt gaaaaagctt
   500041 gtgactgcgc cgcatcagga tcatcgcccg gacgcggttg aggagcgacc gggggtcctc
   500101 tcgctgtgct tcgacattga tccgcttgaa ggcgaagggt ccgtcggtca cgattggctg
   500161 tatgagcctg gcgcgctggg ccgtggaaaa gccggcattg gcgccagcgt tccactgcat
   500221 ggggacgcgg acgggctcac ggcccgggcg ggaagggtct tcgcccatgc ctatttcgtc
   500281 gccgtagagg acaaggggca cgcccggaga agaaagaagc aggctgaacg ccagttccaa
   500341 tctcgtctgg tttccctcga gcatcggtgc gagccgacgc ctgatgccgc gtccgtagat
   500401 ccgcatctcc tcgtccggag cgaaggcggc aaaggtctcc tgctggatgt cttccggcag
   500461 gcggtcgagg ttgagctcgt cgagattgcg aaggaaattg acccagcctc gatggggagg
   500521 cggctccggc attatcgaaa gcgcctgacc tatgagatcg gccttctgcc gcgcgaggct
   500581 tgccgcgaaa gacgcgctca gaacgaagtt gaacagaaga tcgagtttcc cttcaccgaa
   500641 ataggggcgc agcttttcag gcgagaggtc cgcctcgccg agcagaagac catcccggcg
   500701 tctgccttcg accagctcac gcatctcccg caggaagcca tgaggatccc tgggatcagc
   500761 gtgttctatg cccgtctcgc cgatgacgaa gggcgcggca tcaacccgga agccgtcgac
   500821 gcccaatgtc agccagtaat cgaccacgcg gagcaattcg tcgcgcaccg ccggattggc
   500881 gatgttcagg tccggctgga agtggcgaaa cttgtgaaaa taataggcct gggcgagctc
   500941 gtcatacgtc cagacgctgc tttcctcacc gggaaatgcc gtcttgttgt ccggagcgac
   501001 cggcggcggg ctggcggacc agacatagta atcgcggaag cggcacctcg catcccgccg
   501061 tgcggcctga aaccacggat gctcgctcga tgtgtggttg gcgacgagat cgatgatgac
   501121 gcgaataccg tgttcgccgg cagcgtgcag aaagttcagg aagtcgtcca gcgtcccgag
   501181 cgcaggatcg acagagtaat agtcgctgac gtcgtaacca ttgtcggcga agggggacct
   501241 gaagaagggc gacagccaga cgcagtcgat gccgaggtgg ctcagataga ctacccgctc
   501301 cctcagtccg atgaagtcgc cgatcccgtc gccgtttccg tcagcgaacc ttcgcacgtc
   501361 gattccatag atgaccgagc ttgtgaacca cggcgcctca ttcatcatcg gctcccttgc
   501421 aagttccgcg ccgcataagc cgccgtcgca atcgtactgc gtgatcccgt gccactgtcg
   501481 agccgggtaa actgcacgac gacgggaacg tcagcctcta tgaccgctcc gaaatcgacg
   501541 tccagcggca gcgcctcggg aaagatcaga tcattgaagc ggatgcggcg tacccgccga
   501601 gcggcaatct ccacatcata cggtccgaca acggggcgat ccgcatagtg gatctgaatg
   501661 cgcagccggg ccgggctgtc ggaacagttg agaaccgcga tctcgtcgcg gctggtgaat
   501721 tcgggctcca tgccgttact ccccaagggg atgtgccccc cggctatcgt ccatcgcctt
   501781 tttccgatcg cctccatgca ccctcctagc acccgagaag tctgcgcaaa taaggcgtta
   501841 gaaaccgccc ctccgggtcc agctcctgcc gaagggcaag aaaacgatcc cacatcgggt
   501901 agagggcctt gagttcggtc gcgcgaagac tgtgcttttt cgcccagtgc ggccggccgc
   501961 catggtcccg catcaccggt tcgaggtcga gaaagaagtc ccaatagggc agcgtcgcgt
   502021 tctgatggag cgatatgctc acagagtccc ggccataggc ttcgctcagc caggtgtcgt
   502081 cacgcttgat gtaacggtag agcacgcgcc agccgaccga gcggcgccat ttttccttga
   502141 tgcgcgtgcg cagctttctc atgcaatccg gtccggcctc ggccggcatg gaatattcca
   502201 tttcctcgaa gcgataagga agatcgctgt gctgcggaat gacctcgtgc ggcggcccgg
   502261 tctcgtcctt cgccagccgg gcgaaggcgc cataagtctt ttcctcgccc ggcgggttga
   502321 ggcaacggat cttcacctca tcggagcggg gataccaata gaagtcgaag ttccgatttt
   502381 cccgggaaag ccgatcgagt gcctccatgc agggctcgaa gccaaggcac cattcctgac
   502441 ggcggagatc gtgcaagggt tcgagctgga gagtggctga ggtgagaatg ccgagcgtcc
   502501 cgaaggaaac acgcaaggct cgcacgaaat ccaggtcctc ttcgacgccg aaggtggtga
   502561 tctctccccg ggcggtgacc aggcggccgc cgacaagcat catcgaaagg ttggggaagt
   502621 ttcgtccgga gccatgcgtg ccggttccga tcgcgccccc gacggtctgg gttgcgacgt
   502681 cgccgaaatt tgagagcgtc atgcccgccg actgcagctc cttgctaagc tccgtcagtt
   502741 gtgagccggc accgaccgcg gctcggtgac atcgagagtc atgctcatgc agaccacaga
   502801 tattggccag agaaaccagg acatcgtccg tgacgtaaat ctcgctcgaa gaatgtgccg
   502861 agcccaccgg ccgtatggtt cggccctgcc tgccggccgc gcgcacgagc gctgccacgg
   502921 cctcttcatg ctccggcacc tccagacgcg ctggacgaaa gcgcagaccg cccgaccagt
   502981 tgtggcaatc ctggtccagg ttttttgagg ttgcactcca gggtgtgttt gccatgctaa
   503041 tcctggcagt aggcgatcgt gctcaagaga gcgtgggaag gctgccggga atcgagccgg
   503101 gtctgttgca ccacgaccgg cgtgtcggct tcgatcagcg acgcataggg cgtatcccgc
   503161 ggcacgggct ccggatcatc gagatcgttg aagcgaagat gtacggtccg ccgagcggcg
   503221 acggtaaacc ggaacgggcc cgccggctcc ctgtccgaaa aaaacaatgt gatctcgacc
   503281 ttcgccggcg tgtccccggt attcaggaca caggcgctct catgggagac gagcgcggga
   503341 tcgtcgctcg cgctcgatga aggaatatag ccgtcggcga ttgcccatcg cctgctgcca
   503401 atagcatgcg tcattctcaa atcctcaaaa acaaacgctt ccggtcgaac ctaagaaggc
   503461 gagctttgtt ccatcggcgg gccaccgagg cgcgtcgcca caagcgccta cggtatgcgc
   503521 ctacggtatc cctggcaggt caccggtatt ggcgtccggc gccgcttcat gtggtgcctg
   503581 cggctcctcc tcggtgactt tcctgcctgc ggaggaatgc ctgaggtttt cttcgatttt
   503641 ctcatgtccc ggcgtttgcg gaagcgcggc acggaaattg cgggcgtagt cctcgggcat
   503701 tttgggcggc atcagcggct cgtagcgatc gaccagcgcc tgaatgacga ccggtccttc
   503761 ggctgcgaat gcctgatcca gaaccccgtc tatttcgtcg aaggaccgga tcgtgaagcc
   503821 tcggccgccc atggcttctg ccgcagcggc gaagtcgatc ggcggcagct cgcaggcgaa
   503881 ttgcggattg cccaggaaca tcatctgttc ccaggcgatc tggttcagca tgtcgttacg
   503941 gatcaccagg agcttcaaag gaatctcata gcggacggcc gtggcgaatt ctccgagctg
   504001 catggcgaag ccgccatcgc ccaccaccgc gtagatggga cgggcgggca tggcgatgcc
   504061 agccgcgatc gcgtaaggga gacccgaggc catggatgcg agtgcgcccg ataccgcaaa
   504121 catatggtcg gcaccgagat ccacatggcg ggccgcaagt tcggtgtttt gtccggaatc
   504181 tgtgacgacg atgccgtttg ccgcgatgcg cctgccaaac gcgccgaccg cggcctgcgg
   504241 cttcagggga gaactcctgt cgccctccat ggcacgcaat tcacgccgcc agtttcgcgt
   504301 tttctcttgc gcctgttcga gaaacgtccg gtctgctttg cgctgaagcc gttcattgag
   504361 catgcgaagg gtctctcccg ccgcgccgac aagcccgact tcgaccggat agcgaagccc
   504421 gatgcgctgc gggtcatgat cgatctggat tccggtggct gcgtggggct tcggatagta
   504481 ttcgatatag gggaaggtcg aaccgacgat cagcagcgtg tcgcattgct gcatgatctc
   504541 ctgcgacggt accgttccca gaattccgat gcctccggtg gtgaacgggt cgtcgtcggg
   504601 cagcacggcc tttccgagca gggcttttgc caccggcgcg cccaacaggt ccgccgtctc
   504661 gcgcaaaagc ccctttgcct cgagcgcgcc gcgaccggca agaatcgcaa ccttcctgcc
   504721 cgcattcaga aggtccgccg cgcgcagaat atcgtcttcg cgcggcacca gcctgccttc
   504781 gaaaaagcgg ctcggcatgt gcccttcgcg gttgcggcgg gaccgcccac cgccggccat
   504841 acgctcttgc acgtcgttgg cgatcgaaag atgcgcgacc ccgcgcttcg agagggccga
   504901 ccggcaggcg aggtttgcga gattttccat gtgggcggca tcgttcacct gagcattgta
   504961 gacggcgacg ttttcgaaga cgcgggtgag atcgacgtcc tgctgcgaaa aagtctctat
   505021 caggtcatga tactgcatgc cggtgatcgc cagcaccggc atctgatcga gcttcgcatc
   505081 gtagaggccg gtcaggaggt tcgttccgcc cggacccgaa gtggcaagac aaacgccgag
   505141 cctgcccgtg aacttggcat aggcgcacgc catgaaggca gcggactgct cgtggcgcac
   505201 ggagacgaag cggatgcggt cctgccgccg cctcagcgcc tccatgatac cgttgatgcc
   505261 gtctcccggc aggccgaaga ccacttcgac cttccattcg ataagcgtct ctatgagaat
   505321 gtcggaagca ttcggcatgt ctattcctcc tccggccagc gagagcgcga ttttgcgggt
   505381 gatgggttga aggctcgggg ccttctaatc ccctccgccg gggaattgtt ccgccatggc
   505441 ggtgctgcac cgcgagagcc ctgggaagct ttattcggca gctatgctgt tgctggaaca
   505501 aatcacggtt gaaagggatt catttccaat cggaatgcac gggataggaa gcttggactg
   505561 gaaaaacgcg ctcaccggaa atacggccgg ccgattgcga cgggcaagcc ggccgattat
   505621 caaggaggcc gaaaatgtct ggcgcagcgc gcccgcacga catctctcgt tcctcgtgga
   505681 tgcagcagcc tattatgcct gtctcgacac catgttcgag gaagcggaag agcagctgtg
   505741 gatcaccggc tgggacttcg atccgcgcat caagctcagg ccggaagacc cgcatgcgga
   505801 atcccttgga agcacgcttg agcggctggc tgcgcagaag cccgacctga aaatccgcat
   505861 tctcatttgg gcgatgggcc ccatttattc gggaaagtcg ctcaggcttt tccgcaagca
   505921 gcaatgggca gcgcatccgc agatcgagct ccgcttcgcg agccatcgcg cgctgcgagg
   505981 gtcgcatcat cagaagctcg tctgcatcga tgacaggatc gccttcgcgg ggggcatcga
   506041 cctgacggcg cgccgctggg acacgccgga acacgcggca gagaacgagt tgcgtcgaga
   506101 tccggacggc aagccttatg acccggtgca tgacatccag gcgattgtcg aaggcgaggc
   506161 gagccgcgcg atcggtgatc tctgccgcgc ccgctggaca gcctccaccg gcgaagaagt
   506221 cgaagctccg cgtgcgaagg catcaaaagg cgcgcgcaca tggccatggc ccaacggcac
   506281 cgtgccgatc ctcgaaaatt gcccggtcgc aatcgcccgg accgagcccg gctccggcaa
   506341 aaagcgcgcc cgccgggaag cattgcggct gacgcttgac gccttgcgca gcgcgcgtcg
   506401 ccacatctat atcgaaaacc agtatttcgc gtccggaagg atagggcagc tgctctgcga
   506461 ccggctgcag gagccggacg gcccggaagt ggtgatcatc acgacccgaa gctcgcatgg
   506521 gctgctggaa cgcatcgtca tgggcggcaa ccgcgaccgt ctcattcgac ggctcacaca
   506581 ggctgaccgt tacggcaggc tcagggttgc ctatccggcc gttcccgccc ccgacggatc
   506641 cgagcaggag gtgatgatcc attccaaggt ggtcgcgatc gacgaccgct ttttccgggt
   506701 cggttcgtcg aacttcaaca accgctcgga aagcctcgac accgaatgcg atgttgccgt
   506761 ggaagccgcc aatgaaggac accgcgcggc aattgccaaa atacgcaatg gcctgatcgc
   506821 agaacatctc gacgtccatg cggacgcctt cgcagaggcc ctgagggaaa cgagctccct
   506881 catagccgcc atagacaggt tgaacacgcg cccgcgcggc atacgcagct ttgacggaat
   506941 cgacaatggc ggcgcgaccg atctggtctg gggaacggag atcatcgatc cgcagcggcc
   507001 gatccggccc ttttatcgca cgcacaagct gctcaggcgc tgggtcggtc agcttttcgc
   507061 cttgctcgcg aggctcttat cgtcgtcgcg acgggcagcg agctccgcaa cggacagcga
   507121 tatcaagccc agcggcagcg gcaggaagaa atagatcgcc cgaaaggcga tgagagcgcc
   507181 cagactcgcc gaactgccga gcagaaatgc aatcgtcgct tccaggacgc cgattccacc
   507241 gggaacgtga ctgacgatcg cagtcacccc ggcaccgaca taggccattg ccgtgtcgat
   507301 gaaactcacc tcttcaaaag cgctgagcag ctgatgcagg gatgcgctga cgcagaggaa
   507361 gttggccaca ccgacgatca cctgcaaggt ggcgatcttc accgagggca tttcgaagct
   507421 ccagcggaag atgcggaccg aaccgcgcaa caaacacgca agcagtacat agctggccgc
   507481 tgttgcgatg caggcagcgc cgagcagaaa tgcgccgctc gtggacaacc cggtaagccg
   507541 cgcggcgtcc gccggcaccg ccacaaagca aagcccggcc aatgcgataa gcccgaggcc
   507601 cactgtgacc ccacaaaaga gaatgacttt cgcaatctct tcggcgctca agccccagcg
   507661 cgaatagaaa cgataccgga tggcaccgct gctcagggcc gcgccgccga cattatggcc
   507721 gatcgaaagg ctggtgaacg aagcgatggc gatttgcgga taggggagct ttcgcccgac
   507781 atagcgaatg gcgagagtgt cgaacagcgt caggcagaaa taggaaagaa agacgaaacc
   507841 gatgcctgca aagagatccc ggccaggaat ccgcatgatc gaaccgacga tctcattgaa
   507901 actatgctgg ctaagcgttc gatagatcag ccagcccgcc accgcgatac ccgccgctat
   507961 gaacagcctc gctagtattt tcctggacat cggcactccc ttgcgcactc accggaacga
   508021 aatgcaggcg ctgcgtgttc ccgaaagcga tgcgacagcg gatacgtttc ctcacctata
   508081 acgtccacag ctgcttcggc accgaccgca agctcgatcc cgcgcgcatc gccgccgtga
   508141 tcgcggaatg ccggcccgac gtgattgcct tgcaggaagt cgacgtcggc cgcgcccgca
   508201 ccggtggaat agaccaggca cacatgatcg ccacgcatct cagcatggac gctcagttcc
   508261 atccggcact ccacctcgag gatgagaaat atggcgatgc cgtgctgacg gctttgccca
   508321 tgcggttgat cagggctgct ccactgccct cgtccggcga accgcgaggc gcgctatggg
   508381 tggaaattga cgcggccggc gtcaaactgc aggtgatcgt gacgcatctc ggactgcgcg
   508441 gtgccgagcg cttgcgccag gcaacggccc tgctgggccc gggatggctc ggggcaatgg
   508501 agcagggaaa aacccgcttg attctggcag gagatctcaa tgcaaccggg cgttccgcct
   508561 cctacaggct cctcgcccgg cagctcaagg acgtacagct cctcactggc aataagcccc
   508621 ggcccacttt tccttcccgg ttgccgctgc tgcgtatcga ccacgtgctg ataggcgact
   508681 gcattgaagt ggtttcctgc caggtacaca gcagcgccct ggcgcgaagc gcctcggacc
   508741 atcttccgct cctgaccgaa ctagacgtcc tcgcgtaggc gagatcggcc tatccgcctg
   508801 agctgttggt gatggcgggc cgcatgccgc acgaaaacgc cgcggacctt ccgggtgcgc
   508861 ggcgccggca cttccgccga agcgttcgcg gcaaaggctg ttcaatgctt ggccgtcacg
   508921 tctcgctgat cccgctccag gaacctgcgg gtgatctcgc cggcgtgctc gcccagccag
   508981 tccgccatcg cgatttcctg ctgcaagatg ctctcgcaga cccgcttcgt ctcctgatca
   509041 cccgcctgtt cggccgcggc aatgagaatt ttataactcg cgatttccat gtgctcgaat
   509101 gtgtaactgg ccagcgagcc cttgaccact tcgtcactga caaacagacc gctcaggcct
   509161 tgtccgaaag ccatgatctt gccgcttata tccttgatgc tcgaggttcc gccgtccagg
   509221 cgctcgaggc agcgttcgag catcgccgcc tggtcccgcg tctcctgcag gtgacggtcg
   509281 atcctggatt tcagttcggg atagttttcc agccggccgg attggctggt cagcatcgtg
   509341 atcgcctgct cttccatcgc gtgcgcatcc ctgagccaag ccacaaggtg ttcgttcgca
   509401 gtagccatct gatgttcctt tctttttcgc gcgtgctcca accggcagtt tgcggaattg
   509461 ttcctgcggg accgccccgc cgcggccagt cgacggctgc ggaacaattc cagggcttga
   509521 tgatttgaga ccggaaaccg caggttctct ggttcggtct cggcaatggg tcggaagggt
   509581 gcacatgtcg aaaatcgtgg ctgcagcagt gatcgtaggc ctggtactaa tcgcggggct
   509641 ttggatgatg tttcccctcg accaaccggc cgaaccgggg cagcctcctc cgcatgctat
   509701 cgaccaatcg gaatgaatcc ggaacggacg tttgaaaatg acgcgagaaa tccaggaaaa
   509761 actcaagatc taccggctgt cgcccctggc cgagcccgac gatccgaact ggcagaacgc
   509821 cagttaccag ggcgaagtcg tcgttgccgc gagatcaagc ggcgacgccc ggatcgtcgc
   509881 ctcggaggcg gaactcgact ttctggagat cgacgccaag ccggccgaag gcgttacaac
   509941 cgacatggcc agcgcctttc gcagcgaaaa gctctataca gtcgttgagg aagggccggc
   510001 tccggaaggc acagaacgcg gcgtgctcga tggcgtggtc ggtgtcgaca acatcgtttc
   510061 gacgcagctt taggccgatc ccgcccaaaa agatcaagca agtccccttc accggcagca
   510121 ttctagggcc gccaagagtt accagtctca caaaccgaac ggaaatgtat cgggcacgcc
   510181 ggcccttgtg tgttcaggtc cgagcggctc gaccgggttc gtttcatcga accagacgaa
   510241 tgcatcgaac tgccgcggca gcgaggcgtg ggaataatgg ctcaaccgtt ccgtttccgg
   510301 tcggtagatg actccgatga agcgctcgag catcggcttg agaaggcatt cgctcagggg
   510361 cgcgtggcgg gcaaaatcga tgaggaagcg cgctacgcct gagtcgtgaa gcacacgctc
   510421 gtagctccct tcgagcgagg cccggatagt cttcacttcc atgtcgccat cccaatcgct
   510481 tgcggcagcc acacggccgc tatgcgtgcc gaagccgatc agcacagcct gatcgccgta
   510541 gcgctcacgg cagagctggc cgatgttcaa ctcctcgcgg gcagtaccca tgtcggtgtg
   510601 gcgggcgtcg ccgatatgag agttgtgcgc ccacacgacc gccttcgatt gatcgccgcg
   510661 cgcgttcaac aggtgctcga gcgtctcgaa catatggctg tcacgcatgt tccaggagtc
   510721 aggcccggca taatacatga tcctgtaata gcgctcggcc gaggccacca gccgcgcatt
   510781 ctgtaccgcg tcgagaagct cgtcgccgct accgcggccg gcttcgagct gcttctccag
   510841 aagttcccgg cattgctcga cgacggcttc ctcgcatttg cggaagcctg ccgtcatcgc
   510901 agcacggcca tacgtcgatg gttcgttctg ccagggcgtg agacacccgt agcgcgcgcg
   510961 ggcaactgca gccgcttgtg gatcggtctg gtcaagatat cgcaggacgg cggcaatgga
   511021 gccgcggatg ttataaatgt cgagcccatg gaagccggcc cgatcggagg cctccctgct
   511081 gccgttgagc tcgcgcatcc attccacgaa ctccatcact tcgcggttgc gccacatcca
   511141 aaccgggaac cgctggaagg gcgcgtcctg tagcatgccc ggcgctcggt ggcgaacata
   511201 gcggtcgatc gctgcggcat ccggccaatc cgcctcgacc gccacgatcg taaatccatg
   511261 ttcctcgatc agacggcgcg tgatggccgc gcgggcacga taaaattccg acgtgccgtg
   511321 gcttgcttct ccgagcagca cgacccgccg cccggcgaat ctatcgaaaa gccgcccgaa
   511381 ggccggatcg tcgaaggcgg gcagcggttc ggccgccgac gccaccatct gcgacagagt
   511441 gggggccggc ctgaggctct gccttgcccg gggctccgcc cgctcgtcgt gccagccata
   511501 ttcgccgatt agcggcacaa accttacacc accgaggtcc tgctccttaa acgtcgtggc
   511561 actcacgcgc gtgaccttca gcaggcgctg ttcgtccggc ggcccgacgg ggatgacgag
   511621 gtggccgcca agatcgagtt gctgcttcag cgcatacggt atctcgggac ttccagccgc
   511681 aaccagtatg gcgtcgaagg ggcctgcttc cggccaaccg gtggtaccgt cgccgacgcg
   511741 gacatcgata ttcttgtagc ggaggtcggc aaagcgctgc ccggcgatcc tggcgagccc
   511801 tgcatggcgc tccatcgtat agacatgtgc cgcgatccgg ctgagcactg cggctgcata
   511861 accggatccg gttccgattt cgagcaccgt gtcgccgggc tgaacctcgg ctcgctctat
   511921 catcagcgcc acgatatagg gctgcgaaat cgtctggccg tggccgatcg acaacgccga
   511981 atcctcgtag gcgaactctt cgaagcccgg gtccacaaag gcctcccgcg gaacgacgcg
   512041 catcgctttc accacatggt cgttcctaat tcccctccgc gagaggtgcg acgcgatcat
   512101 gcgttcgcgg gctctggaaa aatcaatcat ggcggtgcct ccttgcgtct cctcgcagcc
   512161 cggtactcga tcatctcctt attcgaacag gcgacctggc atgcggcctc ggccgggtcg
   512221 cctgtatcga accgaaacgg gggtgtgcag ccgcgcggga aacttcggac tgccgcctgc
   512281 tgctacaaca gcgccggggg gctgaggcgt tcccgttcgc gtgtcacctc atcgaggctg
   512341 tacgggttcg aagcggcgtc gaaccgggtc cagccgtctt ccgtaaaagc gcgtcgccgg
   512401 aacgatatat cgaccgcatt gcggtttctc agaataccat ccgcttgggc gaccagcttc
   512461 tcatcggccc tgaccaccac tagcgcgctg cctcggcgca cgccctctgc gtaaagatgc
   512521 gcatcctcct cctcgagacc ggagtgggtg agcgtttcga tgatgccgcc ggcacactct
   512581 ccggtgagag ccccggcggc ggccgacgca agccagccgg ccccgacgac aggtccgatc
   512641 cctggtgtca ccatcaggtc caggcccatc aaaagccccg tcgcgccggg cacggcgccg
   512701 ccgctcgtat agcgctcgcc cgcattgttg gcgacgatgc tcatatcttc cgagggaaac
   512761 cccgccgctt cgagatcgct aaccgcccct cgcgcttcgt cgtaatcatc aaacagccct
   512821 gccacgaccc tcatgtcttc ttccttttcc ttctgcagcg catagacggc tgaggagcgt
   512881 gcgcggtgtc gcccgtatca gcgccgatct cttccaaaga gttgagacgt gggatgcggg
   512941 cagggcccag gcttcctcat accgcttcca ggcgcagtca gcggcggctt ccgggacact
   513001 catcagcact gcaaggccta agacgttata cttcaggccc tcgttctcgg gcgcctgatc
   513061 cggcccccaa accttccagg ccggaattgg ttccgccgac ggccgtggcc gagatcaatg
   513121 ggaaacctgc actggactcg gcattgaaga tgcggtcgga acattcgcgc cccttctcgg
   513181 ttgcacctgc gaccgcaggt ttgggtttca gtttggagga agcgcaatgg ctacgaatgc
   513241 aaaggacggc aaggccgcca agagctcgaa agggacacat ggtggaaatc gggcaggaga
   513301 ccaggcgaag aaggacgatg tcaagaaaag cagccagtcg gccgggaagg atccgcagag
   513361 gggcagccga taaggcgcca ttggccacaa tccgcccggg ctgaacgaaa ggaacaatca
   513421 tgctgaaatg ggctctgatt tttttcgtaa tctcgttgat cgccgggttt ctcggcttct
   513481 ccggcatatc ggccgcgacg gcggggatcg caaagatatt gttctacatt gcagtcatca
   513541 tttttctcgt cttcctcgtg ctggccctgg cggttggagg cgccgtaact tagagcagac
   513601 ccattgaatg cagaatccag tcgccgcgtg cctcatccaa ggcttgcttt acagagtagg
   513661 cagcggccgg ccaaggtggt caacgggcgc gccgacctgg tatggccaga gcggcttcta
   513721 tgccgatgtc caggccggct gagctggttc tccagcgatc tcccttctgc cattctcggc
   513781 aatctcgcca gcggcaatga cggcttcggc tatggcttga ttctcgaagc cgccagcgct
   513841 tcgccattgg cgacaactgg gcgctcacgc cccaggcgca gttgagctgc gcctcggtcg
   513901 atttcgacga cttcaccgat ccgtttgccg cccgtgtctc gctcgatgac ggcgacagcc
   513961 tgcgtgcctg gatcggcatg agcatcgatt atgagaatgt ctggcagggg cagcaaggcg
   514021 acacacgccg tatgggggtc tatggcattg ccaacgtcat tcacgacatg tcgggccgta
   514081 tgcgggcccg gatgtcggag gtgacgctcg acagccaacc cgaggaccgg cgagatcggc
   514141 cttggcggca gctataattg gggcgacgac aaatacgcac gctatggcaa gctacgcgcc
   514201 accaccggcc ttaccgactt cggcgacagc catgccctgg gcaccgtcgg actgcgggtc
   514261 aggttctgac ggcattcaga acgaggggac aagtgaaagg gcggcccgcg ggccgcccgg
   514321 aattgcaggc aatcaaaacg ttggagcagt tccgcgctgt tttggcggtg acgggcaccc
   514381 agccccggtc actcgccacc cggctcggtc agtgcaagct cttggagtgc atgcgcagga
   514441 gcgagcgagc ttccatcgcc gaaccggggc gcatggccgc cacatattgc tcggtcagct
   514501 ccatcatcgc gagcgcgatt tcctgccatg accagcccgc ctcttcggcc agggcggtca
   514561 ggacgaggaa ctcatcctct aatgcacgct gacattcaag ctcgcggctg atctgctggc
   514621 tatgaacggt ggggctgatc acaggcatat gctcctccca caacggcgca tcgacagacg
   514681 cgctcggtcg ctgtagcgat ttgatttact tattggtttt gcccttcgct tcggctcggg
   514741 gcactcatgc gatagctgcc agacaaacgc cacgaccgcg ccggcggttc catcacgttc
   514801 gcacctgggc gcattgccgc agaatgatcg gcggattttg caggagtgat tccgcgttgt
   514861 tgaagggcgt gccgcccgtt ctgccccaac ggaacttccg aaagactggc gtgttgtcac
   514921 gagagtcccg ttcatttgga aggccagtat gacatcaatg accccgcaca gcccatcgga
   514981 aggcccctca gagccgctcg cgctgccgca gctcgtggat gaggaagccg aggccttcgt
   515041 cgccgaggcg atcgcggagc tgggccggtc gggaattccg tttctgatcg cggggacttt
   515101 tgccgtgagt gcacataccg gaatatcgcg gccgacaaag gatctcgacg tcttctgcaa
   515161 acccggtgac tacatccgga tcctcaatca tttcaaggcg ctcggatatg ccgtcgaaat
   515221 cgaggacgac cgatggcttg gaaaggtttt caagggcaaa tccttcttcg acgtgatctt
   515281 ctcatcaccg aacggaacca tgatggtcag cgactcctgg ttcgccaatg ctctgccggt
   515341 ggagatcggc ccctccatct gccaggtcgt agcgccgacg gaactcgtct ggtccaagtc
   515401 gttcattcag cttcgccacc gctacgacgg tgccgacgtc gcgcatgtga tcctcaaggc
   515461 ctatgaccgg atcgattgga caagattgct cggttacatg gaagcgcatt gggaggtcct
   515521 gctcattcac atcctgaact tccgctggat ctatccctcg gagcgggaca aggttccgct
   515581 ctggctggtg gacgagcttt tgagccggct ggcggcacaa agagacctgc cactgcccca
   515641 gacgaagatc tgccgcggca ggatgtactc tcgacccgac tatgaaatcg atgtgaagga
   515701 atggggtttc gctgacgtcg gaggcgactc cgacctcagc gcggaaactg aggataagga
   515761 ctgatgagca agctgaaggt ggccgccgtg gcggacctgc atgtaaagga ggaccgatcg
   515821 gtctcctaca cggacctgtt tgcggaagtc tcgcgcgcgg cggatgtgct tgtcattgcc
   515881 ggcgacctga cggacctggg aaagcctgcg gaagcagaac tgctcgccgc ggatatgaaa
   515941 tcctgcacca ttccggtcgt cgctgtgctc ggcaatcatg accatcaatg cgacgccgtg
   516001 gaggaggtct cgtccattct tgtgaaagcg ggtgtgcatc tcctcgatgg tcaaagcatc
   516061 gaaatcgcgg gcgtcggctt ctgcggaacg aagggtttca tcggcggctt cgggcggcac
   516121 atgctgggtg ccttcggcga agcggcgata aagaccatgg tcggaacgag cgtcgacgaa
   516181 gcgatccggc tcgaaaacgc attgagggcg accagggcag agcgcgcgct cgtcgtgttg
   516241 cactactcgc ccattcccga aaccgtcgac ggagagccca aggagatcta tccgtttctc
   516301 gggtcctcgc gtcttgcgga gaccatcgac cgtttcaagg tgagcgccgt cgtccacggc
   516361 catgcccaca aaggcgccta tcaaggaaag acacccggcg gggctccggt cttcaatgtc
   516421 gccgcccatg tcgaaaagcc gacgggcaga ccctacgcca tactcgaact ctgatgcgtc
   516481 atcacccggc cgagcctttc cgcccgccgg cgagccgtca cggtctgagg accaccttga
   516541 tgcagccgtc cttcctttcc gcgaaagtct tgtagagttc ggggccgtcg gcgagcccgc
   516601 cgcggtgggt caccacgaat gagggatcga tctcgccctt ttctatgcgg tcgaggagcg
   516661 ccggcagata gcgctgcaca ggcgtctgag ccattctgaa cgtcagcccg cggttgatcg
   516721 ccgaaccgaa cgggacctta tcaagatagc cgccatagac accgacgacg gaaacagtgc
   516781 cgaagttcct gcagcaatgg atcgcctgtc gaagcacatg tggccggtcc gttcccatga
   516841 acgttgcgac cttcacgcga tcgacgaggg aacccaggct tgcacggctg tcagcctccg
   516901 tccccaccgc atcgatacag gcatcggccc ccctgccgtg cgtgatctcc atgatacggt
   516961 cgtaaatgtc ctccgctatg taatcgagcg tcacggcgcc ggcggtctct gcaagtctca
   517021 gccgctccgc aatcgtgtct atcgcgatga cccgctcggc gccgagcagg aatgccgaac
   517081 ggatcgccat ctgtcccacc ggaccgcaac cccagacggc tatcgtctgg ccaggctcga
   517141 tgtcgcagaa ctccgccgcc atatagccgg ttggaaagat atcggagagg aagagcgcct
   517201 gctcgtccgt cagctcgtcc gggaccttga tcggtccgac atcggcgtgc ggcacccgga
   517261 gatactccgc ctgtccgccg ctatagcctc cgaggagatg ggagtagccg aacagaccgg
   517321 cgggtgaatt gccccagagc ttcgctgcct tctcccggtc ggggttggtc cgctcgcacg
   517381 ccgaatagaa gcccttccgg cagaaaaagc actccccgca ggaaatggta aacggtacga
   517441 ccacccggtc gccaaccttc agattggagg cgccgctgcc gacttccacg acctctccca
   517501 tggtttcatg gcccagaacg tcgccattct ccatggatgg gatgaggccg tggaaaatat
   517561 gaacgtccga tccgcaaatc gcacaggccg tgaccttgat gatgacgtct cgttcatcct
   517621 tgatttcagg atcgggcacg ctctcgcaac ggatatcgcc cttgccgtgc catgtcagcg
   517681 ctttcacgtc ggagctcctt gtcaatcgct ggaagaaaaa gaaaaggacg gcgctctgct
   517741 cgtccttcac attcctccaa acacggagct ggggcaggtg ttcccaggat cggaggtgat
   517801 cgaagccgga tgcccgcacg aagcgggctc cgggttcgct ccaaggcgat cacacgacga
   517861 gcacgaaatc tcctgcagtc agtcccggct gtgtagagag gactgcaaac tgcacggccg
   517921 tatgccccga aaggttgccg tcagcatcat agtagagcgc gcccgtcgtc gtatcgtaaa
   517981 cgactctttg gttcacgcct tgcgcctccg ttgcgccggc cgccgcgtag aactggttgc
   518041 ttgccagcga accgccgctc aggctggtga aaacgctctt cgacagaaag agccggtctc
   518101 cggcggtaaa atccagaacc atgtcgacat tgctcgctcc caaagcgaag tcgaactgga
   518161 aaatatccgc ccccgcgccg ccggacagca tgtcgcttcc gccgccgccc gacagcagat
   518221 ttgcattgcc gtcgccgctc aggctgtcat tgccggtccc gccccagacg ttctcgatat
   518281 tgcggaccgt atcctcggcc accccgccga ccatgacagc cgtggaggcg gcaccgttga
   518341 gggtgacgga aaccgatgca ctcttgtcgc ggtagttcgc cgtgtcggag gccgccccac
   518401 cgtcaagaat gtccgctccg ccgccgccgg taagcaaatc cttgccgtca ttgccattga
   518461 gggtgttggc ggagtcgtcg cccgtcagcg tatcgttgcc cttgccgccg aatacgtttt
   518521 caatgtttcg gattgtgtct tccgcgaccc cgccgacgaa gacgaagctg tcaccggcgc
   518581 cgaagagggt cacatcgaca gccgccgcct tctcgcgata atcggccgta tcggaccccg
   518641 ccccgccatc gatgaagtca gcgccgagcg ctccacgaaa cgtgttgctc gcgccatcgc
   518701 cgacaagtgt gtcggcaccg gaccccgcca atatgttttc tacaccgcga atgacgtctt
   518761 ccgcaactcc gccgaccaag accgtcgcgt tcgtggtccc gttgagcgtg acggagatcg
   518821 cgtcggcttt ctcgaggtaa tccgcagtgt cgatgccatt gccgccatcc agcacgtcac
   518881 tgcccaagcc gcctttcagc gtatcggcac cgtcattgcc aagcagcaca ttggccaggt
   518941 cgtcgccgac aagcgtgtcg ccggccgaac cgcctgcaac gttttcgaag ttgcggatcg
   519001 tatcttcgtt aaggccgccc accttgacaa gcgcggcatt cgcgccactg agcgtgacga
   519061 caaccgacgt caccttgtcc cgataatcgg ccgtatcgac ccccgcgccg ccgtccaggc
   519121 cgtctgcccc ggccccgccg cggattgtgt tgctgttgcc gtcgcctgtc agcacgtcgg
   519181 cgccggcgcc tccgaagatg ttctcgatat tgcggaccgt gtcctcggcc accccgccga
   519241 cagtggctgt cgtattagcc acacccgcaa gggtcaggac gacggcagcg gtcttgtcgc
   519301 cgaagtctat ggtgtctgat ccgctgccgc catccacaac gtcctggccg ccgcccccct
   519361 ttagcaggtc ggcgccgccg cctccgagga ggctgtttgc cagcgcatcg ccggtgatca
   519421 catccgccag ggcgcttcca gtgatgcttt cgacgttgcg caacgtgtcc tcggccgcgt
   519481 tgcctatgaa caccctcgcg tcaatggcgc cgttgagcgt tacagcgatc gccttcgccg
   519541 aggccgaata gtcggccgtg tcggtacccg ccccgccatc gaacacgttc tgcaagccgt
   519601 cgccaacgaa cacgtcgttg cccgaaccgc cgatgatgtt ctcgatgttg cgcagcgtat
   519661 cctccgcgat gccgccgacg aggaccgttg ccgggctcgc gccggccaga gttacgacaa
   519721 gcgatgacgt cttgtcgctg aagtccgccg tgtcgctgcc ggcagcgcca tccagcacat
   519781 cggcgccgag gccgccacgg aacatattgg cggcggcatc gcccgtgagc tgatcgtttc
   519841 ccgcaccgcc gatgatgttt tcgatgtttc ggaccgagtc ctccgccgtt ccgccgacgg
   519901 tcgcaacggc atcgatcgct ccgttgaggg caagcacgac ggattgcgcc ttgtcgctga
   519961 agtccgcggt atcgctgccg gagccgccgt caagcgcgtc ggcgccaaga ccaccgcgaa
   520021 acgtgttggc agcggcatcg ccgctgagcg tatcgtctcc cgaacccccg acgatgtttt
   520081 cgatcttggc gatcgagtcc tcggcaaggc cgccgactgt cactgtgacg ggattgccgc
   520141 cattcagcgc cacgacgatg gcagcctgct tgtcgctgta gtccgccgta tcgctgtcct
   520201 cgccgccgtc cagtatgtcg gcaccgctgc cgcccatgag ccagtcgttg ccgcgcgcac
   520261 ccgagagctt gttggcggcg gcatcgccgg taagcgtatc gcctgccgat ccacctacga
   520321 tgttctcgac gttgcggatc gtatcctccg caacgccgcc gacgaagact gtagctccat
   520381 tcgcaccatt gagctgcacg aggacggagg atgtcttttc gcgcaggtcg aaggtgtcga
   520441 ccccgttgcc gccatcgacg gtatcgttgc cctcgccacc gaacagggaa tcggcgccaa
   520501 tgccgccatt gagaatgtcg tttcctacct caccgcgaag aatgttgtcc cgatcatcgc
   520561 ccgttaggat gtcgtcgccc gaaccgccat agacgttttc gaagttgctg atcatgtcct
   520621 cggcgatgcc gttcacgaaa actgtcacag gtgtcgcccc ggccagcgtg accacgacgg
   520681 aggctgtctt gtcggtatag tcggccgtat cattcccgcc gccgccgtcg agcacgtcgt
   520741 ttccgccgcc tccccggaag agattgttca gcgcgtcgcc ggtgataaag tcgtcgccgg
   520801 agcccccgta aacgttctct acgttggcaa gcgtgtcctc cgcgacgcca ttgataaaga
   520861 cggtcgccgc cgtcgcaccg gtcaatgtga ctacgattgg ggccgccttc tcgcgatagt
   520921 cggccgtgtc cacacccgcg ccgccattga tgatgtctgc gcctccaagt ccctgaagca
   520981 ggtcgtcgcc ggctaaacca ttgaggctgt cgtccgaacc cgtgccgatg agaatattgt
   521041 ttccagaagt gccgttgatg actgccattg gaatccctcc ctgaaggctc ctgatgagac
   521101 gctggaacgc tgcgcccacg gcttagagaa ttagtgaaag aaacgagcac tggtgatgat
   521161 gcgcttcttg ggtgttttcg ctcacgcaat cccaccgggt accggcgcgg gattcaaaaa
   521221 ctgtgcggct gtccgcttcc cgctcgaaat gcaacaatca atattgttca atggcgtggg
   521281 gccggctcga cctgagcatc tggtcttggc ggttcctttt cacgaaattg cattcagccc
   521341 tgtttcgaaa gtccagccag agcgaaagca ggcggcgagg taatgcggag ccgggccccg
   521401 cgctcatacg cgattggacg gcgatcctct tcgccgtcta cttccgaatt gttcggatcg
   521461 ctgaagtgca tcgtgctgtc ccggtcgcat ttggttgcgc aagatatccc tgtgggatat
   521521 tgccaccgca aacaaccggc gggaatatac cgaaccatat agtgataaag actatctcgg
   521581 acgtcggagg atactcggaa ctcagcagaa attgtctgcc cactattttc cgggaaacta
   521641 ggatctctgg tcttgactat atattgatcc ggacgaattt ccctcactat tcgcgcggac
   521701 ggcgcgctga ccccattgcg aactcaggct ttcagagtgt tggtgtactg aacgtgaagg
   521761 gcggcaagcg tcgcgcgatt gctgatgtcc agcttgcgaa agatattgtg caggtggatg
   521821 ccgatcgttc cctcggatgt tccgagcctg gatgcgatca tacggttgga caggccgccg
   521881 cagatcagcg ctgcgatctc acgttcgcgt ggcgtcagca gactgaacct ttccagggtc
   521941 acatcttcgc tgacctggga cgccttctcc atcagatcgg cgggaagcca ctttccgccc
   522001 atggcaacct gccgcatgca gtccagcagc gcttccggcg catattcctt cagaagaaga
   522061 ccggagaggc ccatcttcag cgcttccgcg acctgaggtc cgctgatggt ggcggtcagg
   522121 aaaatcactc tcgtaaaacg gtgggtaccg cgaagcgccc tgaggatctc caatccgccc
   522181 atgcccggca tggccacgtc aaggacggca atatcgggct ggaggcggga tatgagtgag
   522241 atggcttcga ccccgctcgc ggtcgcgccc acgatggtga agtccggcgc cgcggcaatg
   522301 atgtcttgca agcccctgag gagcaacgga tgatcgtcga cgagcagcac cgtatgcatc
   522361 atctgagccc cggctttagc ggcagcgtga tcgtcagacc gatccccggc gaactccggc
   522421 aaattgccag actgccgccg agttccgcaa tacgttgcga cagcgagaag ggcttcttgg
   522481 acgtgagtcc atccgctatt cctgtgccgt tatcggaaat atccagttcc agaaggcctg
   522541 cgctcccgat aaagccgatc cgcaccactg tggctcgtcc atggcgcact gcattggcga
   522601 cagcctcgga aatcagctgc attatctcga aaagcatcca tcgcgggacc atcattccag
   522661 gcgatccgat cgaaacgtcg atgctgcaac tccactgcat tcgcagaagg tcgagaaatt
   522721 ccggcaggtc ctgatcgagc ctcgcgagat tgccctcctc tccgggccgg ttctcatcga
   522781 cgaatttgcg cacgcattgc tgttgctcga gaatgagcga acccacctcc atcagcttct
   522841 gccttgcgcc atcggggaaa gcttcaccga tgagcttcag tttgaggcgc gcggccgtga
   522901 gattctgaag cacgctgtca tgcaggtcgc gagcgagtcg cattcgccct tcggcacggg
   522961 cagcctggat gagagcgaca cgctcgagct ccgtcccgac gcgcgttgcg atgatctgag
   523021 tcaggtcttt catgtcgtcg gttgaatttg cgtagcttat aacgaaaacg cggccccggt
   523081 aacggaggct cgaaaaggcc gcggaaacca ccttgcaatt tggccggccg gcattcgcgt
   523141 ggatctgggg cagatcggcg aaaaggccgt tcagggcctc accgctcctc gaatggcgtt
   523201 cgtcgcagcc atcgggatca tggcgccgcc agaattcagg atccctcagg tcagccaatt
   523261 ggagccgacc actcgtccag aatgcggcgc atccggactc gaactcctgt tcgcgccaga
   523321 tgacgagcag atgcgcatct cccagaacgc cggaagcatg ctgcaggacg atgctcaacc
   523381 aggacaggcg gtcctcgccg atcgcgccag acggccattg cgcgagctgc gcaaggcgct
   523441 gccggcttcg ttcccgatac gccccgaaat agccgagcgt cgccgcgata agcacaaaat
   523501 agatcgaacg catgatgaat atgttgagct cggcgtcccc atccaggaga tcgggaagcc
   523561 ccaccacgag ctgaacgatc agcgcgatca gcgcccccag cgaggcaccc ttgagccccc
   523621 agcgcatcgt catggcaagg atcacgaaag gcagaataga gaagaacggg ctcgccagtt
   523681 cgttcgtcag aaaggtcagc caaccgacga cggcggcgtc gacgccgtgg atcagcaggt
   523741 gcacggggct gacgaacgaa aaccgcagtg gaaaaaacac cagggcaacc gcgaggagaa
   523801 ggtagaggcc gagaacaaga cgagactcgt aaagcatcga gttcggacgg gtgggatcga
   523861 gatagatcgc cagtatcgca aagactgcgg tgatcacgcg acccaggcaa atcaggcgtt
   523921 ccgggtcggt acgcaacaac cattcacgcg ccgccccggc aaattccttg gcgggacgat
   523981 acgcacgcaa agtcgcgtca ttccgggtga tcgccatgcg tacttcgcct tcacgcaatc
   524041 gcgtaaataa aatatgtatt agtatgcggc gatcttcact gcgaacgggt cgaaagtcaa
   524101 cgacgcgaaa gaatctccgt cgcttgcggg tttccccttt tcatcccgga cctaggtgcg
   524161 cctgaagaga cgcgcgacgc cggagtggcc tcggcgggcg gcggcgccct gcctgccgag
   524221 aaccagcgcg gcgactgcaa ggcccacaac gcaaaccgcc gcggtcgcag cgatcggaac
   524281 ccggtggcgc gagcggaggc ctccgtcgat ccccccggct actgcgggcg gcctgaagag
   524341 attgccgtgg ctggtggccg cacgcggcgc ccggctcaaa tagcgggcgg tcatgcgcgc
   524401 catgagccgc gtcgtggttt caggggcaac gaaatgtgca aagcgcgtca ggtcggcgac
   524461 aagacccacg gtcagtttat tacgcgggcg ttctgccaga cgaaggatgg cgcgagcggc
   524521 acgacgtgca ttgtagacgg gaggaggaac gctgagcctg cggccggtat agttggcgcc
   524581 gtgcacgacc ccgggcgtat ccaggaaagt cggatatacg tcgcagatgt gaatatcgcg
   524641 ctcctcggcg agctcggcac gcagcgcttc ggaaaagcct cgaaggccga atttgctggc
   524701 gctgtaggcc gcagcgaagg gcgcagaggc gaagccgccg agtgagatca tgttgatgaa
   524761 ggtgccatgg ccctgcttcc gaaaaatcgg tatcgcggca tgcgcgtcgt tgaaatgacc
   524821 gatcaggttc gtgcggatga cctgttcatg cgcttcgatc ggcgtttcgt cgaagcggcc
   524881 gactgcgccg acgccgacat tgctgaacca gacgtcgatc ctgccgaagc tcatcgcctt
   524941 cttggcgagg cccttgaccg cctcggcatt ggtcacatcc gtcggggcga cgagaacctc
   525001 cgctccaagc tttcggcagg ttcgggccac ctcgtgcagt gctgccgcgt cgcgcgccgc
   525061 cagcacgagc tttgatccgc gtcgtgcgaa ggcttcggcg gtggcctgcc ccacacccga
   525121 cgaggccccg gtgatgacga ccaccgcacc ttcaagattc aacatttcgc tcctccattc
   525181 gcggatcgca ggcgccgcaa ccgcacccga tcgggtcgac ccgatctgaa acatcatgat
   525241 ctagcgcttc gtcttacccg catccgacag cttgccacga tgcggatcct tcaggttttc
   525301 gccgacggcg tcgcggtcgc gttccgggtc gtccttggcg gggagatagc ctctcgggcg
   525361 tgtctccttc ggtccttccc agcggggcga ctgctcggtc gtgccgggtg ccccttcctt
   525421 tggcgttttc atcgttttct ccattctaca agtcgaaccc gcatacacgg accgcactca
   525481 ttcctggtcc ttcatgtcgg gcaggggatt gcgttgatcg gcatcctcga gatccgattt
   525541 gacgatgtac tcgtccctct tcaggcgcgc cgcctcccgc gcggccttgg cattcgtgat
   525601 gtcgtccggt tcaagagggg gctttccggt ctccggatgc aggtcgctat cgttttcgac
   525661 aggccgttca tcgggcttga catccaaagg gtccggcatc tggcgcttgg tcttctccat
   525721 catgctctcc tgctgcacaa ttcctcgggt cagtgggggc aacgtgaagc cttgggcgaa
   525781 gttccatgcg cgctcttccg aagcgctcga gcccggaaca aagggtcgtc tgcctgagtt
   525841 agggccgcgt gttgcgggga aagccccggc gacgccgatg ccattccaga aagagctttg
   525901 cctagacgca gcctgccaag gagttcgtga ccatggaaag atttccgcag cctcccttcc
   525961 cccgccaaaa gcaggaaatg cctggcacca ccgaccagat gcagccgctt cccgaccacg
   526021 gtgagaactc ttaccagggc tccggacgct tgagagacaa gagagccatc atcaccggcg
   526081 gggacagcgg tatcggcaga gccgtggcgc tcgccttcgc ccgggaggga gcggatgtcc
   526141 ttatcagcta tctgagcgag catgaagacg ccatggccac caaggccctg gtggaggaag
   526201 cgggccgcaa ggcagtcctc gccgcgggcg acatccaatc ttccgaccat tgccggcgga
   526261 tcgtcgaaac ggcggtccgg gaactcggcg gtgtcgatat tctcgtcaac aacgcggccc
   526321 accaggcctc tttcaagaac atcgaggata taagcgacga ggaatgggag ctgacattcc
   526381 gggtgaacat gcacgcgatg ttctacctga ccaaggcagc cgtgccgcac atgaagaagg
   526441 gcagcgtcat catcaataca gcttccatca atgccgacgt cccgaacccg atcctgcttg
   526501 cctatgccac gacgaaaggc gcgatccaca atttcagtgc cggtctcgcg cagatgctgg
   526561 ccgagcgcgg gataagagtg aatgtcgtag cgcccggtcc gatctggacc ccgctgatcc
   526621 cctccaccat gcccgaggat agcgtcgcca acttcggcaa gcaggtgccg atgaaacgtc
   526681 cggggcagcc ggtagaactc gcctcggcct acgtaatgct cgcggatccg atgtcgagtt
   526741 acgtatccgg cgcgaccatc gcggtgaccg gcggaaagcc tttcctgtga gcgagctgaa
   526801 gctgcgagcg tttctgctga aacgccctac agcgccgtgg gtcttattag acgcagacgg
   526861 tcgctgtagc gcttcgatct gctgtccaaa tcaatatgaa atgaaaattt catattgatt
   526921 ttcatcggaa ttcgtattcc atttcctccc gactcaaaga tctggccaag ggaggttatt
   526981 tccgtgaaac gtctaatgtc cgctgccgtc ctggcgctca ttgccggcac ggcccacgcc
   527041 gaaaacatcg gcatctcaat tgcccgttcc gacagcgcgt tcctcaccat tctgcgtaat
   527101 ggcatgcagg atcaggctgg caagctcgat ggcgtcaccg tccaggtgga ggacgcgcag
   527161 aacgacacca gccggcagct cgaccaggtg cagaactttg tctcctccgg cgtcgatgcg
   527221 atcatcgtcg ttgccgtcga cggcgatggc acgccggcgc tgacgaaaat agcgaccgat
   527281 gcgggcattc cgatcgtcta tgcgaatcat ccgccggccg atgtcgacaa gctccccgag
   527341 acggcggcct tcgtcggctc caacgagatc gattccggca cgctcgagac gaaggaagtc
   527401 tgccggttgc tcggcggcaa gggtgcggcc tacgtcctca tgggaccgct caacaaccac
   527461 tcctctctga tccgcacgaa agacatccat gacgtcatcg ccaccgacga atgcaagggc
   527521 atgagcgtca tcgaggagca gagcgccaat tgggaccggc tcgaggccgc caacatcatg
   527581 acgaactggc tctccgccgg acgagagttc gacgcggtga tcgccaataa tgacgagatg
   527641 gcgatcggcg cgatccaggc catgaaggcg gccgggatcg acatgtcgaa ggtcgtggtg
   527701 ggcggcatcg acgcgacgcc ggacggattg gccgccatgg ctgccggcga cctggacgtg
   527761 accgtctttc agaacgcgat cgctcaggga gcggccgcaa tggacgccgc agtcgcgctc
   527821 tcgcgcgacc aggagaccga gcggcagatc tgggttccct tcgaactggt gacgccggag
   527881 aacatgaagg actacgcgac ggcaaatcag taaggcggca acggcgggag accccctcgt
   527941 cccccctgcc gggacgttct ctccgcaagc ggacggaggg gactcgcggc agcattccgc
   528001 acgtcttcac cgccgcatgg aagtcatgtc gccgcgtgcc acttgtccct tctccccgtc
   528061 agaaacgggg agaaggtccc ggcgggagat gaggcgcccg tgccctgcac ccgccgaatg
   528121 aactccgccc gcaccaacgg caaaactgtc ctccattcgt gaatttcatt cacaggcatt
   528181 gcgactggcg aggtgcttat cgcagtcgcc cgaatgccgc atatttcacc gcgaaacgtc
   528241 aaccatcgct aacatcttcg agcccgcttc gccttggcga ttggcggctg gaaaggattt
   528301 gtcatgcctc tggcaatctt cgcattgacg atcgcggcct atgcgatcgg caccaccgaa
   528361 ttcgtgatcg tcggtctctt gccgacggtc gcaaccgacc tcgcgatcag cctgccgctt
   528421 gccggcctca tcgtcagcgt ctacgccctc ggcgtcacgt tcggggcgcc ggtgctcacg
   528481 gctttgtcaa ggcggatcga acgcaagccc ctgcttctcg gcctgatggc gctcttcatc
   528541 ggcggcaaca cggtggccgc actatccccg aactacgaaa tgctgctcgt cgcccgcgta
   528601 ctttccgcct tcgctcacgg cgtcttcttc tcggtcggcg cgacgatagc cgccgacctc
   528661 gtgccggaag accgccgcgc ttcggctatc gccatgatgt tcatgggcct cacggtcgcg
   528721 atcgtcacgg gcgtgccgat cgggacctat atcggccagg ctttcggctg gcgggccacc
   528781 ttctggggcg ttgctgcact cggcgtcgta gcctttgccg gaattgccac cctgctgccg
   528841 ggctcgctca ccaaagccgc tccggcgagc cttctcgacc aggtgcgagt gctcggctcc
   528901 ggcaggctgc tgttggtctt cgccatgacc gcactcggct atgggggcac cttcgtcgcc
   528961 ttcacctttc tggcgccgat cctgcaggag gtcaccggct tttccgaaaa cagcgtcagc
   529021 ctgatcctgg tgctctacgg cgtcgcgatc gccggcggca acatcgccgg cgggcggatc
   529081 gccaacacca accccgtcaa ggcgctcatc ggccttttcc ttctccaggc gctcgtattg
   529141 gttatcttca gcttcactgc cgcctcgccg gcactcactc tggtgacact taccgctctc
   529201 ggcttcctgt ccttcgccaa tgtgccgggc ctgcagctct acgtggtgca gcttgccaag
   529261 gagcatcgcc ccggtgccgt cgacgtcgcc tccgcgctca acatcgcggc cttcaatctc
   529321 ggcatcgcgc ttggcgcctg gctcggcggc cgggtggtcg gctctccgct cggacttgcc
   529381 tccaccccct gggtcggcgc aatcctcgtc tcaggcgcgc tcctgctcac gctttggagc
   529441 ggccttctcg accggcgcgg cgagtgcggc gagcctttgg ctgcagcaaa ctgaggcgtg
   529501 ctgaagacgg cctgccgcga gatgcggcag cgcacaattc ttcattgcgc cgcgcccagc
   529561 caatgcttat aaagcgggaa ctcaccccgg acccggtgaa accccgggtg gctcttctgg
   529621 ccgccgatcc gccagacaac gcaacagcat caaaccgtag cgagccggat agtccgccgg
   529681 ccgggtgtgc tactattgcg aagaaaatca atgaagctga catttacgag ttataaacgc
   529741 gaatggttct ccaacatccg cggtgacgtc ctttcaggca tcgtcgtggc gcttgcgctg
   529801 atcccggagg ccatcggctt ttctgtcatt gccggcgtcg atccgaaggt cggcctgttc
   529861 gcctccttcg ccattgcatg cgtttccgcc ttcaccggcg gccgtccggg catgatttca
   529921 gcggcgaccg ccgccaccgc cgtgctgatg gtgacgctcg tcaaggaata cggcctcgaa
   529981 tacctgtttg ccgccaccct gctgatgggg ctcatccaga tagccgcggg ctttctgaag
   530041 ctcgggcggg tcatgcgctt cgtgtcgcgt tctgtcatca ccggattcgt caatgcgctt
   530101 gcgatcatga ttttcatggc gcagcttccc gaactcatcg gcgtgccgca cgtaacctat
   530161 gcgatgatcg gggcggggct cgcgatcatc tatctcttcc cctatgtcac caaggcggtt
   530221 ccgtcgccgc tcgtcgcaat cgccgccctg acagcgatcg ccgtctggac cggcatggac
   530281 atccgcaccg taggcgacct cggcgaattg ccgtcaagcc tgccgatctt cgcccttccg
   530341 caggtgccgc tcaccttcga gacgctgcag atcgtcttcc cctactcggt gggacttgcc
   530401 gcggtcggac tgctcgagtc ccttttgact gcgcaaatcg tcgacgacat gacggatacg
   530461 acgagcaaca agagccagga atgcatcggc cagggcgcaa gcaacatcgc atccggcctc
   530521 atcggcggaa tgggcggctg tgcgatgatc ggccagtcgg tcatcaacgt gacctccggg
   530581 ggacgcgggc ggctatcaac cttcgtggcc ggtgccctcc ttctctttct catcctcgtc
   530641 ctcgacgaca tcgtgcgcat cattccgatg gcggcactgg tggcggtgat gatcatggtc
   530701 tcaatcggca ccttctcctg gcgttcgatc ctggacctgc gccgcaatcc cctgccctcc
   530761 tccgtcgtaa tgctggcaac ggtcgttacc accgtcggaa cccatgatct cgcaaaaggc
   530821 gttctggtcg gcgtgctctt gtccgggata ttcttcgccg gcaaggtcgc gcgcctcttc
   530881 catgtccgct cgatacttga ccaaagcggc cgggagcgca cctattacgt cgacggccag
   530941 atcttttttg cctcgacgga gggtttcgtc ggcgccttcg atttcgccga accgctggac
   531001 aaggtcgtca tcgacgtgag cggggcgcat ctatgggaca tcaccgcagt cggcgcgctc
   531061 gacaaggtgg tgctgaaata tcgtcgccac ggcgtggcgg tggaggtgat cggcctcaac
   531121 gaggcaagcg cccatatgct cgaccgcttc gccgtgcacg acaagagcga agaggcgggc
   531181 gcggccctca ctccagccca ttgaatttcg ccgtccccgg gttgaatcgg atcatcccgg
   531241 ggttataagt tctcatccct tccgcctgtt cggatcgcgt atatcctcac gatcccctct
   531301 ctcttcctac cctgcagtcg agagccctca tgccgttttc gaccttcctt gtccgaaatt
   531361 gccgatggct cgcaggcggg tttctgcttt gcttcttctc ttccttcggt cagaccttct
   531421 tcatatcgct ctctgcgggt gacatccgcc gagagtatgg cctcagccac ggcagcttcg
   531481 gtactctcta catggcggcc acgcttttga gcgccctgac ccttccccag ttgggacgga
   531541 tcgtggacca catccgggcc tgtcatgtcc ttctgctgac gctgccgctg ctggccttcg
   531601 caacgctctc gatggcctat gcctcgacct ggctctggct ctttgcaacg atctatctgc
   531661 tgcggctgtt cggtcagggc atgatgacgc acaacgccat gacagcgatg ggccgatggt
   531721 tttccgcaca gcgcggaagg gcggtttcaa tcgcgagcct cggcaaccag gcgggcgagg
   531781 cgttgttccc cctcgtcttc gttgcactcg cgccacttat aggctggcgg cagacctggc
   531841 ttttttcggc tgccgccatt ctcctcgtcg gtctcccggc gatctatgtg ctcatacgga
   531901 ccgagcgaat gccaagtgcc agcgacgggc ccgagcgccg gttcgcggcg cggcattgga
   531961 cacgctcgga ggtcctgcgc gatccggttt tctggttcgc gctctccggc gtgcttgcgc
   532021 cgggtttcat cgccacgacc atctttttcc accaggtcta cctggtcgag cttcgccact
   532081 ggtcgctcga ggtgttcgcc ggagcttttg tcgtgtcgtc taccctgacg gtggtgtttt
   532141 cgttggtcac gggttacctg atcgacagat attcggccgt cgacatcctg cctttctatc
   532201 tcgtgccgct cgccgccgct tgcttcaccc tcgcattcat cgattctcaa tggagcgcct
   532261 tcgccttcat ggcgctgcta ggggcgtcgc tcggctcgtc caccaccctg ttcggagcac
   532321 tctggccgga gatttacggc gtgcggcatc tcggcagcat acgtgccgtg atcgtcgcgc
   532381 tgatggtgtt cgcgacggcg atggggcccg gcatcacggg ctttctaata gacgccggcg
   532441 tcccctattc gtggcaaatc gcaggcatgg gcatctactg cctgttcggc atattcgtga
   532501 tgaatgcggt ccggagcgaa gtccagtcgc gcaacacggt gctgccggca gaagagtagg
   532561 aaccgcaccc ttattcgtcg atccggaagc ccaccttcat caccacctga taatgcgcga
   532621 ccttcccgtt tacgatctga ccgcgaatct cgtccacttc gaaccagtcg agattccgcg
   532681 tggttttcga agcacgcgaa atcgcgccat cgatggcttc ggttatcgag ttcggtgagc
   532741 taccgatcag ctcgatcttc ttatagacgt gctcgcccac ggtttcctcc tgaggggttc
   532801 tggttgcatc cgggccccgc tgcaggggcg cgggcccggg acgacagcgc aatcgccgcc
   532861 agcgtcaatc atgcctgcgt tgagcgcgaa ccgccagaga tcgaacaaaa ccggcatcca
   532921 tcgcgcctgg gcccgctgcc atcggatgga aagtgctata ttctgcgtac tggcctacgt
   532981 ccaacgcggc gttcctgcga aacccgcgca cggcaaggaa ggaggctttt atgctgccta
   533041 cccgacgctc ccttctgacc gcatttctcg ccgtgcccgc gctgcccgtt tgcaatcgag
   533101 ccgcggctca gcaaccgaca ctaccgctca cgcccgcttg ccgcgacgat gacgacctga
   533161 cgcccgcact tacggcgggt ccgttctaca agcccgatgc gccgctcagg cacgaccttt
   533221 ccggcgacgc cccggacggc gaacgcatca ccatcgccgg ctacgttctc gacggaaatt
   533281 gccgtccgat cgcccgcagc ctcgtcgaaa tctggcatgc ggacgagacc ggcgcctacg
   533341 atacgcgcgg ctacaggcta cgtggacacc aggtgaccga tgaacgggga cgctggtggt
   533401 tcagcaccat cattccggca ctctaccccg gacgaacccg ccattatcac ttccgcgtgc
   533461 gccgtcccgg cgcccccgtc ctgacgacgc agctcttctt tcccaacgag ccccagaacg
   533521 acggcgaccg cctttattct ccttcgctgc tgctcgacct gcgcgacacg gaggacggca
   533581 aattcggccg cttcgacttc gtggtttgac gccaatgtcg cgaccggcgg gaagacctca
   533641 gacagcttag cttttcgcac tcgagttcgg gttgcgcttg tctccgtcac tgacgccccc
   533701 tttcgaggct ttggagccgc cgccccactc ctgcgccttg cgggcctcgt cgccgcccac
   533761 gtgacccggc tgttttttct tggcggtgcc gctttctccc ttgttcttcg ctctgtccgt
   533821 tttctcgtcc atatcggcct ccatccgctc tgctcgatcg gtcggcacat ccactgtacc
   533881 ggcagggtct gacactgggg ccgaacaagc ggggaagcga tcggttcctc ggcgaaggac
   533941 gcggttcgat cgacgctgcg tctggaacat tcgacggggg cgcgggtttg ccttcccgtc
   534001 acctgaaagt acccagacag gagaaaggtc tgatgtccga taccgatagc gaatatggag
   534061 cgccgggcgt cggcccctcg gccgaaggcg ccgcgcggac cagcacgata accgccttgt
   534121 tcgacaaccg ctcgcaagcc gaggccaccg tcgagcgcct ccgcgaagcg gaactcggtg
   534181 ctgccactgt tcaactggtc ctcggcagcg gcgagggctc tgcgcccgcc gcaccggacg
   534241 gcatctggac cgcgctggag aacttcttct ttcccagcga ggatcgcgag atctacgccg
   534301 aaggcctgcg ccggggtggt tatctcgtca cggtttccgg gatcgacgat gccggctaca
   534361 tgactgcgcg cgacatcctc gacgacgagg gaacgatcga cctggacgag cgcgtcgacc
   534421 tctggcggcg cgacggctgg agcggctggc agcgcagtac ttcgccgggg atggatacaa
   534481 gggctccgac ggaagaaacc tttggcgccg ccgccggtga tcacgccagc cccagcatca
   534541 cgcgagacca tgcccgaagt tccgcgaccg tccgggcata ccggagcgaa gcgggtgcaa
   534601 agccggtgga gagttccggt gatgcttcat ccttcaccaa ccgtgacgaa ggacagcctt
   534661 tcggcgagcc atcctacggt gcaccggcga cggagcgagc cgggggcgac aggcttggaa
   534721 aggatcgcgt gggttgggat ggagaccggc cacatggcag caatggactt tcgccatcag
   534781 gcagaaactc agagtaaagt catgcctggc gcaaacctca ttacaggtag ctgcctttgc
   534841 ggcaagcggc gctatgcctt caaggggccg ccttcgcacg tcggatactg ccactgctcc
   534901 atgtgcaggc gcgcgacggg cgggccgttc accgtcctcg tgcgaacgga ggggtcatca
   534961 gtgcattgga acactccacc cgccctctac cgctcgtccc cgatcgcggt cagagggttt
   535021 tgccccgatt gcggtagtcc gctgtttctt caatacgacg acgaccccag gctgcggttc
   535081 acggccggga cactcgactg gccggaaggc ctggctccaa cagatcatta cggcgttgag
   535141 agccggcttc cctgggatga cagcggtccc agccttccgg cggaagaaac caaggaacga
   535201 ttctgaccct gccctgccgg aggcacaccg tccccggcag gaaggccgtg atcttaccag
   535261 ggccgccagc tattcgacca gtaacggctc ttcagatcgc tcagccggtc ctcgatatcg
   535321 gcgatcagat cttcaatccg cgacgaactc cgcgaatgcc agtaaggacg gctcgtgcct
   535381 gcagcgagca gcccgagcag gccgatcact gcgagtgccg tccaggcggg gtgctccctt
   535441 gccatttcgc ccgctcttcg gcccgtattg gcgatcgccc taccggaaga aatgcccagc
   535501 tccgagagcc tttcgctcag cgcattcacc tgctcgcgca gcgacctgac ctcctcttcg
   535561 atgctcgctt gattcggaac gccgaccgat ccgttcttcg tatcgacgac cccccgcggt
   535621 attgtggaac cgagtcgctt ctcctgtgcc atatgttcat cctccgtgtc tgggtcctaa
   535681 ctcgtcaggg atagctaccc ggaaacggcg ggcgggggcc gggagttcct tttcaggtgg
   535741 aaattggatt tggcgcaagg cagagagcaa tcgtctggcg ctgattcaaa gccggttagg
   535801 gttgcagtgg attgaagatc atcgcgaact tcgttcctcc agcggaagcg cgatcatcgg
   535861 ttcatgttgt cgctaagccc gcaacgccaa tgccatttgg ctgcgagcac aagcggcgtg
   535921 accgcggccg ggaggctccg gcggcgatcg agagggctgg ctccggtaac cgctgagcaa
   535981 cggttatgtt cattcagtag aggtcgccgc ccggtttcga gcggcccagg atcacagcga
   536041 tgaaagggcc gctcccaagc tctttacctt gtggagcgcc cctgttctgc ttgactattt
   536101 cgcagggttt gggccgatcc gcttgccgtg agcgacgcgt tccgcggcct tgtggaccat
   536161 ggtatacgca taatctatgc ccatgccgta ggcgccggaa tgttccttca cgagcgtcgt
   536221 gacggcgtca taggtctcct tccgtgccca gtcacgctgc cactcgagca gaacctgctg
   536281 ccaggtgacc ggaatgacgc cggcctgagc catgcgatcc atggcatatt tgtgcgcatc
   536341 ggccgacgtg ccgccggacg cgtcggcaac catgtagatc tcgtaatcgg ggacatcgtg
   536401 gagagctgaa agcgcgaagg tcgtattgca gacctccgtc cacagaccgg agacgacgat
   536461 cttcttgcgg ccgtttgcgg cattctttgc caaagcatca cggacgttct ggtcgtccca
   536521 ggagttcatc gacgttcgtt ccagaatgtc gttttcggga aatacggcga gcagttccgg
   536581 gaaggtgttg ccggagaagg attccgtctc gacggtcgtg atggtcgtcg ggacgttgaa
   536641 gatcttggcg gccttggcaa ggccgacgac attgttcttc agcacctgcc gatcgatcga
   536701 ctggacgcca aatgccatct gcggctgctg gtcgatgaag atgagctggc tgttttcggg
   536761 ggtcaggact tcgagcttag acactttgat ttctccgttt gaagtttggt tgccgttgcc
   536821 ggcatttaat tgcaagcctt cgccggtcgg ctgcctgagg caggcagccg tctttgtagg
   536881 gccatggacg agtgggtcgg aaggcgagga tcagatgcgc cggcttatgc tgccagtggc
   536941 tccaggccgg cctcgatctt ttcgcggaag ggctcatagc gggtcggcag cttgagtgct
   537001 tccccgagat gagcggtatc ctcatcccgg tcgaacccgg gctcgtttgt ggcgatttcg
   537061 aacaggatcc cgccgggagt ccggaagtag atcgcccaga aatagtcgcg atcgatgact
   537121 ggcgtcacct gataaccggt atccatcagg gctttgcgaa cctccaactg cttttcgcga
   537181 ttttcgaccg cgaaggcgat gtggtgaacg gagcccgcgc cctgacgcgc gaacggtgtc
   537241 tgggggagcg ccactaggtc gatcgtggcc gcgccgttgc cacctggagt agtgaaccgg
   537301 gtgacgtccc cctcgacctc ggtgcgttca taacccatga agcgaaggag ttcttccgtg
   537361 gccgcagtgt catgcagatt gaatcttgcg cccgagaagc cgcgaatggc ctcttcctcg
   537421 gagatcccgt ccacaagcca gggagcacgt gcatcgtcga ccgtttcgat caaggccagc
   537481 ctatcgccat cgggaccggc gaagcggagg cgctcgacac cgaaggtcgc gtcggcctga
   537541 atgccgccca cgccgtaagc aataaggcgg tccttccaga aagcgagcga tcccttagga
   537601 acggagaact gcgtttcacc gacctcaccg acgcccgggc gaccggtcat catgtgggag
   537661 aacgggaagt aggtcatgac cgtgccgggc gtgcccttct cgtcaccgta gtaaagatgg
   537721 tagacgctgg gatcgtcgaa gttgacggtc ttcttcacac gccggaagcc gaggacgtcg
   537781 gtgaagaacc tgttgttctc ctgtgcatcc gacgccatcg aggttacgtg atgcagtccc
   537841 ttgatatcct tgatcatcgt tgcgccctct tgttcgagtt gttcgtctct gttgagtgaa
   537901 ggtgtagccg ggttgattgg cgcaaggaat tgtaataata attgccagtg aattgcgttt
   537961 tttgaaatag ttggaatgaa cgactacaaa gctttgaaaa tctttctcct cgctgccgaa
   538021 aagcggaatt tcgcgcaggt cgcgcgcgag ttggacatga cgccagccgg tgtcacacgc
   538081 gcgatagccg ccctggaata tgaccttggc atccaactct tcgtgcgaac gaccaggcaa
   538141 gtttcgctga cgacagacgg tgccatcttt gccgctcagg tccagccagc cgttgctgtc
   538201 ctcgataatg cgcgacgcga cgtcaggaat gcgaacaagg ccgatcaggg gcgactgagg
   538261 attagcgccc caacatggct cggcaagacc attctgccgc ccatcctttc aggctttcgc
   538321 gaactttatc cgaagatgag tttcgagatc tcgttgtcgg atgggctggt cgacatcgtc
   538381 gacggtgact acgatctggc aatccgcata tcgtcggctc catctgacaa gttcacgatc
   538441 tggcgcaaga tcagcgtcgt ccgacgagtc ctggtcgcgg caccgggaag ccgattccat
   538501 gctatggagc atcctggcca gttgtcgccc gacgactgtc tggcctatag cggcgagagc
   538561 cgacgcgaaa cctgggtgct ttctgacggc ggatccagca tgacgatttc agccggccgc
   538621 gcattcagcg ccaacagtgg agaggtgctg gccgatatgg cggctgatgg tgccggtgtc
   538681 gcaatgctgc cgggcttcca cgtcgccgaa catctgcgaa ccggaaggtt ggttcatatc
   538741 cttcgcgagt ggtcgccgca ggatctgtgg ctcacactgt actatccgcc ctaccaggcg
   538801 ctaccgcccc gcatcgcatc cttctcgaaa ttcttcgaac ggcagctccc agcgcacatg
   538861 gcaatgctgg aatagaactg acgtgcagcc cggtgccggc tcggacttta acaggtgtat
   538921 tgcggcgttg cctgaggctt ggtttcagcc gtttcacgtt gcctttttac cccgacggcc
   538981 tcgaacagac gaggacgaac cggcggtaga aaaatgttct cagcctgttt ctaaggtctg
   539041 cattcctgcg ctgggcagcc gcaatcggcc ggcgggacgg cagcaagatg ttttcaaagc
   539101 cggcggcctc gatcagaggc acaagccttt cgactgtgag accgtcgccg aagggcagac
   539161 gctccatgat cttcgcgtgg cgttcgctca tggccccgtc ataatgcggg tcgtacccga
   539221 tgatgcgctc gagggcagcc accgcaagcg aggccagccg accgagcggc gtaggcttcg
   539281 accagtcccc atcgaagacg agcagcctgc cgccgggctt cagcaggcgg agccactctg
   539341 caagcgcctg ttccggctcg gtgagggtcc agacaaggtg ccggcagacc acggcgtcat
   539401 aggttccgtc cggctccatc gtgcgttcgg catcggccag tatgaagcgg accttatcgt
   539461 tcccggcatg tttgcgccgc gcgaccgcga gcatggtctc ggagaaatcg agcgcggtca
   539521 cgtcatgccc gagcgaaagc agcacgccgg tcacttcgcc cgtcccgcat gcgagttcga
   539581 gaaccttcag cggccttgcc ccaagtgcgc tccgcaccgc cgccgcccag gcgtcgaact
   539641 ccggcccacg tggaatgcga tgaccgaaag cgaggtcgaa ggtttccgac cgcttcgacc
   539701 agtattcgcg gatgtcatcc ttcagatggt ggttgcgaat gtccatgata tcaggctccg
   539761 acagcggcaa ttgcggaaaa cgggcgcggc tgccggcgtc ttgcgcggta gcggatgaag
   539821 cagcttccgt cgaattcctg ctcgacctcg acttcgatcc cgaagactgc gcggatgcgc
   539881 tcgaccgtca gcacctcctg cgggcggccg agtgccacaa gccgaccgcc ctgcatgacc
   539941 gcgatccggt cgcagaacat ggcggcgtga ttgaggtcgt ggagagcggc gaccaccgtc
   540001 cggtcctggc ggcggacgag atccagcagg ctgatctgat ggccgatgtc gaggtggttg
   540061 gtcggttcgt cgaggagcaa aatcttcgat tcctgcgcca gtgcccgcgc aatgtgcagc
   540121 ctttgccgct caccgcccga gagcgtgtgc cataggcgat cggcaagatg gcccatgtcg
   540181 acgttcctca acgccgcgtc gacgattgcg tcatcctgag gcgaccaggg cgaaagcggc
   540241 ccgagatagg gtgtgcggcc gagttcgact gcctggcgcg cggttatccg ctcgccggtc
   540301 tcggcctgtt gttccaccag tgcgagcctt tgggcgaccg cacggcggcc gagcgcagcg
   540361 atcggagaac cgtccagaaa cacctctcct tttctcggct tgcggatccc ggcgatgagc
   540421 gacatcaggc tggtcttgcc ggaaccgttc gggccgatga tgccgagaaa ctctcccgtc
   540481 tcgagggtca gggagacctc cttgaggatg tcggtcccgc cggccgacca cgagatttcg
   540541 cgcgctgata gagtcatgcg cggtccctcc tttgtccgag tataagtgcg aaggccgggg
   540601 caccgacgag cgccgtgatc acgccgatcg gcagaacctg gccagggatg agaatgcgcg
   540661 acaaaatgtc tgcaaggatc atgaagacgg caccgatgag cgccgcagcg gggagcagaa
   540721 cgccatgccg aacgccgacg agcatgcgcg ccgagtgggg gatgacaagc ccgacgaagc
   540781 caatcgaacc cacgatcgag accatcaccg ccgtcatcat cgccgagacg ccgacaagcg
   540841 cgaaataggt ccgtcttacc gaaatgccga gcgaggcggc cgattccgac ccgaaagtga
   540901 aggcgtccag tgaacgtgca tgccagagac agacgacgag acccagaagc gttgccggca
   540961 cggcgagcca ggcatccggc caacgcacgc ctgaaaggtt gccgagcagc cagaacatga
   541021 tgccgcgcgc ctgctcggcc gtcgccgcct tggtgacgat gaatgaggtg agcgcgttga
   541081 agagctgaga tcccgcgacg cccgccagga tgatcgctgc ggtgccgcga ccggctttcg
   541141 ctgcgagcag gctcaccagg acaaaagcga ccagcgcgcc gatgaaggcg ccgagcggca
   541201 gcgtcaacag gccggcgccc accccgagaa tggcgacact gaccgccccg gtcgatgcgc
   541261 cggccgagat gccgaggatg tatggatcgg ccagcggatt gcgcagcaac gactgcagca
   541321 ccgctccgga aagcgcgagc gcggccccgc aggacgcggc cactaccgcc cggctcagcc
   541381 gatagctcca gatgatgccc tcgtcgatcg gttgcagagg atagccggca ttccacaccc
   541441 ggttcgcgac tgtctgcgcg acggttttga atggaattgc cgtttcaccg atcgcggcgc
   541501 ccaaccagag cgccgcgatc agaatgagaa gcgctgcgag gaccgcgccc acgcgtcccg
   541561 tccccgttcg cccggccaat gtcagcacgc ggctcacttg gccagtcctg ccctgtcggc
   541621 cagcccgccg tctgagccaa gtccgctttt tgagccaagt ccgcccttcg aggcaagtcc
   541681 ggcctccacg atggcctccg ccagcgcttc gataccatcg atcgtgcgga tcgtcgggtt
   541741 catcgcctgt gcatccatgc cgaacacgtg gcccttggcc acagccggca tgaggctcgc
   541801 caccggatcc cccttcagga attcgagctt cgcctcgagg ctgtcgagcg gatagcgacg
   541861 gcgttccatc gaaccggcaa cgatcatgct cggctcggcc ttggcaatgg tttcccaccc
   541921 gaccgtcggc cattcgtctt ccgtcttgat gatattttcg atcccgagcg ccgccatgat
   541981 gtagccgggg gcaccattgc tgccggcgac ataggggtcg gcatcggcag cgctggagaa
   542041 ccagaagacc gccgacaact ttccctccac cgacgcgacc ttggcgcgcg ccgcctcttc
   542101 ccggctcttc agcccggcga cgaccgccgc gcccgtgtcc tgaacgtcgt agatctgcgc
   542161 cagttcacgg atctcccgat agacgagatc catggtgaat ggctgacggc ggacaccgtc
   542221 gctcgccgca gaattctcct tgccggtgca atcggccggc gaggtataga ccggtatgcc
   542281 gagctcctcg aactgctccg gcctggcgac gacaccttcc gggccgacct gccactgaaa
   542341 ctgtaccgcc accatgtccg gcttcttggc aagcacgctc tcgaaactcg gatcattgtc
   542401 ggccaggcgt tcgaccttgg cgttgatttc ctcgtagcct ttgagcacct gaccgaccca
   542461 cagggctgtg ccgacgacct tgtccgcaag cccgagcaga tagagaattt cagtgctgct
   542521 ctgaccgatc gagacagtgc gcgtcggcct tcgctcgaaa gtgacctgcc gtccgcaatt
   542581 ctcgagcgtc agcgggtaag ccgtttcggc agcagcggca gggctgccga agccggatat
   542641 gccgatggaa aaaaggatga ggcccgcagc gagcggccct ttgagaaaac tgttcatgaa
   542701 cattccccta atgtgatggg acgccgctat gcggccgcga aaatcagtcg gccgattaaa
   542761 cggttccggc ggacgatcgg catccgtttg caaggggaca gcaataaaag cttgcgcggc
   542821 agggcgcagt aggtggtcat ggcttagctc ctgttccggg catccccgcc cgtgacgatg
   542881 gatcgaattt gacggcaggt ctcctggctc acggacagaa gtcgctcatc taccttcccg
   542941 cgcgtcgcgc agtggctggt gcctcggcac cacgaggatg aacgacgatc cgcttacagt
   543001 tgcgggggca gccacggttt tggtcccttt tgggtcgtcc gcaccgtgtt ccctattaat
   543061 cccctccacc tctcgggtag gggaaccgtc ggtcccagtt aatgtggaac gcagccgccg
   543121 gtcaaggagg gaggcgacgt ttgtgtccgc acatgcgacc ggctcatgcc gcggcaatgc
   543181 ctggtcacgc atgggactta tgttatacca ttacatttgt caacggcgcc tcgtcctgag
   543241 gtcgcccttg gcggcggcga ggacaggaga tcggtcggca gcgcgccgat gaaggcaggc
   543301 acggccgagg acttcgcttg cgaaaatgcc cgccggcagc gcgtcgcaat tgatcgcgac
   543361 gaagggacct gccgagcgcc ggctttgcca gtgcgccgga ggcctccgag gagaagagtt
   543421 ggagcattca atcgtctcgg cgataccctg agcgtttccg ggtatcgccg tcgggccgtt
   543481 cagaatcggc tttgcgcggt gcctatcggc cgcgcgtccc cttgcatacg cgccgctcgg
   543541 cctgcgcctt ccgctcgacg tgctggactt gcctcgaaaa tctcaagctc cagccgttcc
   543601 cactggcccg gcggctgcgg tcgccggatt gcgtgcgagc agccgtggag cctggcttcg
   543661 cagggcgcgc tctcaatctc gatataaggt ccgccgggtc gatggttatc gccagcatga
   543721 agccgatcgg cgcgagcatg taggggggaa ttcccgtcgg tacgctcgca aaggcagcga
   543781 gtgaaacaac ggctataatg caaatcacgt tcgtaagcgg gtgggtaatt gtcctgatgc
   543841 agatttcaga aatagtatta tttcgttcgt agtccgacaa tgccatggga gaaatccatc
   543901 cggtctgagt tgtccttcgc cgagatcacg atgactttag gccctgtcga cccaaagtca
   543961 tggaacgtga ccggtgcaag gagccagagc ggtatgcggc cggcggaacg cccgcgcatc
   544021 cgcttcaagc tccggcggcg cttggaggaa tatggactgt gaggcgcccc tggcaaccgg
   544081 cctaggactt ttgcccagac gagctcggac caaggtccta tagatgggtg cggatcgcac
   544141 cctagcttcg tgccttccca cctatacaag aacctagacc ttttcagcga tatctggggc
   544201 ggggttttgc cacgatggca gaacccctcc ttggatcgac cggctgagga ggcatcgaag
   544261 ccttcgggaa cttcgaatat ggaaatgcga gtgcccgcgc aggggatgac gcgggcactg
   544321 caacaggttg gggtcctgaa tgtcgctggg ggacagaagc gacacctgtt aattcttcaa
   544381 acgtcaattt gttccaagcc ggtgacgggg cgcgaaaagg cctcgcccgc taccgcgaat
   544441 cgatgccggt aatcacctcg cgacagcccg acgatcctat ggaacagctt gcgaaaggcg
   544501 gccgcgtcct cgtagccgac tgcccaggcg acctgttcaa ccgaacgtct ggtgaactcc
   544561 aggagttccc gcgccttacc gacgcgcaga tgctgggcat attcgatcgg cttcattccg
   544621 gtcgccgcct tgaaacggcg caggaaagta cgctcctcca tcgccaccac ttttgccatc
   544681 tgcgcaacgc tgacggcgcg agcctcacgc gcttgcagcc aatgctgcac cttcaggatc
   544741 acttcgtcgc cgtgattgag gcgcggcgaa aagctggaat agtgccgctg ctcgcgtccg
   544801 gcggggtcga taagaaggaa acgcccggtc tcgaccgtta ccgtcggacc gaacagacga
   544861 tccacgaggc gcatgccgag gtctgtccat gccatgaggc cgccggcagt tacgatgtcg
   544921 ccgtcctcga tcacgatctt gtccgtgtcg agccggacat ccggaaaccg gtcacggaaa
   544981 gcattggcga agagccagtg cgtcgtcgct ggccggccct tgagcaggcc cgtcgccgca
   545041 agcacgaagg tcccgccgca agtcgatgcg agggtcgcgc cttgggcatg cccgtcgagc
   545101 agccagcgag catagggcgc ggcctcctcc gcttccatcg gcccggtcaa cctgccgggg
   545161 acaagcagta tctccggcat ctcccgtgat ccgagttcgg gatgggtgtc gaaacttcgc
   545221 gcaagacagc cgtcgtcccg aagccgccag tgactgatcc gtgccaccgc cccgccccgc
   545281 tcggcggaga attgacgggc tatgttgatg aggtccgtca tgccgtgaac catcgccatc
   545341 tggcagcccg gataaagcat gagaccgatt tcagctttcg agcgcagcgc tgcctttggc
   545401 atgtggtacc tctttgtcgg tttcggcccg tctaatgtcc gatccgccaa tcccgatcat
   545461 ttcgcaaacg gcctaaatct tcaagcacgg ggcgcgcggc acatgcagcg agcctctgga
   545521 aagagaccaa ccactgaaga ggatgaagaa aatggctaag atcaccatga aggacggcac
   545581 ccgcatcttc tacaaggact ggggccctcg caacgcctag cccattgtct tctcacatgg
   545641 ctggccgctc acggccgacg tctgggaccc gcaaatggtc ttcttcgcaa gcaagggcta
   545701 tcgcgtcgtc gctcacgatc gccgaagcca cggccgctcg gaccaggtgt gggacaacaa
   545761 taccatggac caatacgccg acgacctcgc cgagttgatc gaggcgctgg atttgcgtga
   545821 cgtgatcctc gtcgggcatt cgacgggcgg cggcgaggtt acccgcttta tcggtcggca
   545881 cggcaccggg cgtgtggcaa aggtggcgct gatcggcgcg gtgccgccgc tcatgctgaa
   545941 gaccgaggcg aaccccggcg gcctgccgat cgacgtcttc gacggcatcc gcaagggcac
   546001 ctacgataac cgctcgcaat tcttcaggga tttggtcacc cccttttacg gctacaatcg
   546061 cgagggtgcc gtcatctcgg agggtatccg cgagagcttc tggctacagg gcatgatggg
   546121 cggcctcaag ggccatctcg acagcatccg cgccttctcc gaaagcgact tcaatgccga
   546181 cctggcgaag ttcgacaagc ctaccctggt gctccccggc gacgacgacc agatcgtgcc
   546241 gatcggcgcc tctgcgcatt cgaccgtcaa gatcgtcagg cacgccgtgc tgaaggttta
   546301 cgaaggcgcc gatcatggcc tgacgcagac ctatcaggac cgattcaacg cagacctgct
   546361 caagttcatc gaaatctgat caccgacagt acccggcgtc tatatcgtca gccacctcca
   546421 ggcgcagcgg cgatgccgcc gccctcccgg cgctcggcgc cggccgatgg ctcggccaat
   546481 ggcaggcggt ttttcttata accaccgcgg cgaccagcat cactggcttc ctcttcccct
   546541 tcagcgggat cacgcccgca ctggtggtcg gtgcgatttc cgtcctcacc ctcggcgtcg
   546601 cctttgccgc actcgttgct ttgacgcctc gcggctgggc gaggccggcc tatgccgtaa
   546661 gcgcgacgtt cgcgctctat ctcaaactct tcgttcttgt cgtgcagagt tttttgaagg
   546721 ttccggcact gcaagtgctg gcgccgacgc aaaccgaagc tcccttcgtc gtggcgcgaa
   546781 tccttctgct ggtggcaagc atagggctcg gcaaagccgc ggccgtcggc tcgcgacagg
   546841 cggccctgcc gctgcgggcc gcgcgcggtg caggcgcctg agcttggaca tggcggagct
   546901 tcaattccgc aacgaccgga agcgcgctgt accgatatgg cgcgcttcgg tcaatgttcg
   546961 ttggccggcg ccccatgcgc ggtaacgatc gcctgggctt ccttgccata gagttcctcg
   547021 aaatggtcga agctcttggc aaaatagccg atgccctgag tggcggatct gagcgagcgc
   547081 gccagatcgt cgagagcgct gcccggtaga agggcgcgga agatgtccca ccccttcgcc
   547141 tcctcgtccc tgtcaaagcc gagaacctgg cccttcagcg aggcaacgat cgggaccaga
   547201 ctgcccgaat agatggacgg gacatggaca tcgacgcgaa aaaccggctg catcagcacg
   547261 gaagcggcct gcgacaatgc ctgccttacg ccaagcttcc cggccgtccg gaaagcatat
   547321 tcggaactgt cgacagaatg gtgctggcca tcggtcagca tcacgccgac gtcgatcact
   547381 ttgaagccga gagggccctt ctccatcgcc tcgcgtgcgc ccgcctcgac cgcaggaatg
   547441 aagttgcgcg gcaccgcacc gcccttgacc gtctccgcga aagaaaatcc atcgcctcgc
   547501 ccgttcggat gtacgctgag cttcacatcg gcgaattggc cggccccgcc ggtttgcttg
   547561 cgatggcggt aatgaacttc cgaggatttc gacacggtct cgcggtagac cggactcggt
   547621 ggccgatcgc tcacctcgac atgaaagacg tccgataaca tcctgcagac ttcgcgcagg
   547681 tgtaccggcc cctgagcgca aacaagctgc gcccctgtcc cctcctcctg catcacgttc
   547741 aggccgcggt ccgtctcggc gagtttagcc agggtctcgg agagcttggt ctcgtcgcgc
   547801 tcactcgcag gcaccaatat ccgctcgagc atgggggtcg gtggcgtcgt ccaatcgggc
   547861 ggagcgagtg ccgcaccggc cgtcagcagc gagggcacgg gcaggtggtc ggatttcacg
   547921 gccgcgaaga gctggccagc ttccgtaacc cccgaaccta tcggccggcc gcttgcggga
   547981 tcctgcagag caccgaggct ggagccgcca agagcagctc cctgtttgac accgttttgg
   548041 agggcgcggg cgagaaccgt cttgccgacg ctctggcggt aatgggcatg gaagctgacg
   548101 gcgaggaggt tcgcttcgcc gaccccggcg ccggcagcca gacgtttcct cagcgcttcg
   548161 gcgcgcggcg cctcgtggcg gagcgccttc atcagcctca tcaggccgtt gctgtgactg
   548221 gccgagccga gtagcactgg gatgatcttg ttttcgttca gaactcttgt cgagatcgaa
   548281 tagatggcat cgcttccagg cgcgcgatcc tcgatgagct cctccagcag ccaatcgtca
   548341 aattccgaaa gatgctcgag cagctctgca cgcgcctcgt tctcacgttc ggccgcactt
   548401 tccgggattt cgaaaaggga ggaaggctgg ccctcgcgat agcgccaggc gcgttccgag
   548461 atgagatcac agctgccgat gatcttgtcg ccctcgcgaa tgggaacctg ccgcaggatg
   548521 agtggccggc tgcagaaatc ctgcaaggcg gcgacgatat ctcttatgcg ccctcgtggc
   548581 tcgtccatgc gattgacgaa gaggatgcag ggcgtgccgg acgcctcgat catgcgcaaa
   548641 taaggggcgg caagaacggc cccctccagt accggcgaaa cacagagaac gcaggcgtcg
   548701 cttgcgagca gcgcgtgctg cgcatgcgcg agcgcctcgt tattgccgga gacgtcgagc
   548761 gcgcaccaga cttcaccacc gaattcgaat tcgacgaggc ccaaaccata tggagtaact
   548821 gatttcttcg gctcgccttc cagcgagcca accctttcca cgagcgtgga ttttccgatc
   548881 tgcgaaggac cgagtacagt aaagcagcgc atcggcgttc ctccctctgc caggatgaca
   548941 ctgaggacag gatgcccctg gacgcgcgaa agcgccagag caggatgagg aaaagtctaa
   549001 gcggtcgcgc tgggtgcgaa ttcggcgatg agctcgtggc ggtcgcccgg ataggtgagc
   549061 agcacgctcg tcaccggtac gccgccgctc caagtccggc gctcgatgac aaggcaggcc
   549121 gcaccgatag caatttcgag cgcctgcgcc gtcgtacggc ttgccgcaac ggccctgatg
   549181 cgatgttccg ccgtgctcca gggcaccttt ccaagcagcc acgagcctgg ggcggcggcc
   549241 tcgaacgtct cggtctcggc ttccggtacc gccgaaaggt tgatcaggcg ctcttcgaga
   549301 caaaagacgc gcccgccggc gaaatggctg caggtaatgt cgagaagccg tgacgatccc
   549361 ggcagatcga tgcgcccctt gtcgccggaa gtcatcttgc gcaccaccct ctcgccgagc
   549421 cggtaggcgt aatcgagccc gagcgactgc acctcccgct tgacttcgtg gatctccatc
   549481 accgcggatt gggcttgcgg aaaactgaca tagctcccgg atttgcgccg ccgctcgatc
   549541 agtccccgct tcacgagttc gctcaaggcc ttgttcaccg tcattcgcga gcagccgtat
   549601 tgctgtgtta attcgtgctc gaagggaatg cggtatcccg gcggccagtc gccggaaaga
   549661 atatggccct cgacctcgct cagaattttc tgatgaagcg acaggggctg ttcctggcgt
   549721 ttttcttcgg tgtaggcacg attgctggaa atggtgggac cctcgctcgt aaacggcccc
   549781 gtaccttact catttcgcgc cacgaggaca gcccttctga gtgcgtcttg aagccccgac
   549841 actccgatcg gcagatcgag tcctatggag aattgccatc ttctttcatc aggtgatcag
   549901 taaaagagat gccatggccc caggaaagcg cgtgcccact cctgatcccg ttcgccgtcg
   549961 ctcggcgccg tctcccggca gggagagact tccgccggtt tatcgatcgc tgcagtcttg
   550021 cgtgctgcgc tgccgcgtac gggtggcacg aggtagccga gggtcattcc gccgagatag
   550081 aacatgccgc atcccttctc ttttccgacc ttgcggcacg atcctgccag aatgcgggct
   550141 tctgtcaata gtctactaca tttatgatct atcgggatgt gctccggctc ccgtctccgt
   550201 ctccgatcgc tcagcccgag ttgtccgcgg acaaccaatt gaggagcgga aagaaaaaca
   550261 gccgcgctcc gggcggcaca atcggggttt ttgttaagcg tttgtaaaat ggcaacgaat
   550321 cggcgcatag tataactgcg cagatcagct tttatcggcg aatttagcgc agttttcgga
   550381 gagtagggat gttgcagcag agaatccaga gtcttgaaga gcaggagcat ctgccgtcgc
   550441 tcttgtctgc cgacgctcgg gaactcgctc accagttgca ggagcatcaa aggaagatct
   550501 tctctccgac ttcgcagaaa acgatgcggc tcttcagccc agccgaggca gcggccttca
   550561 tcggaatcgg cgagggctat ctgcgccaga tcgcctcaga aggacacggc ccgcagccgc
   550621 tgtcaaacgg ccgccgcatg tatacggtgg aggacatcga ccgcattcgc cgagttctcg
   550681 acgaaggcag caaaaccggc aaatatattc ctcaccgccg gccgggcgaa aagctgcagg
   550741 tcatctccgt gatgaatttc aaaggcggct cgggcaagac gaccacgtcc gcgcaccttg
   550801 cgcaatatct tgccttgcgc ggctatcggg tgctggcgat cgaccttgat ccgcaggcat
   550861 cgctctccgc cctcttcggc catcagccgg agctcgatgt cggggaggga gaaacgcttt
   550921 atggagccat ccgttacgag gcccctcgcc ccgtggcgga ggtggtgcgc tcgacctata
   550981 ctgctaatct tcacctcatc ccgggcaatc tcgaacttat ggagttcgag cacgagaccc
   551041 cgaaggcgat gatcgcgggc tccgccgaaa ccatgttctt cgcacgaatc ggcgaggtgc
   551101 tttccgaaat cgaaggcttc tacgacattg tcgtgatcga ctgcccgccg cagctcggct
   551161 ttctgaccat gtcggcgctc tgcgccgcaa cctccgtgct catcaccgta catccacaaa
   551221 tgctcgacgt tatgtcgatg tcgcagtttc tgtcgatgac cagcgaactc atggccgtcg
   551281 tcgagaatgc cggcgggcgt accagctatg actggatgcg ctacctcgtc acgcgtttcg
   551341 agccgaatga cggcccgcag agccagatga cgggtttcat gcgggcgatc ttcggcaatc
   551401 gtatgctgca gaatgccatg gtgaaatcga ctgcgatttc ggatgccggc gtgaccaagc
   551461 aaacgctcta tgaggtggag cgcgcgcagt tcatacgcgg cacctacgac cgtgcgatgg
   551521 attcgctctc gctcgtcaat gcggagatcg aagagatgat ccgcaaggtc tgggggagga
   551581 agtaaccgat ggcacgcaag aacctgatcg gcatttccga cagctccgcc gctcccgggg
   551641 acggggagcg cccggccgtt ggccgcccga tcgcgggcct cgcttcccag cgatcgaatg
   551701 gcctcgtcgg cggcatcacc agatccctct cgaacatcac acaaaaggtc gaacgagcgg
   551761 aagaactaga gcgccagctt gttgaagggc acgcgatcgt cgagctcgag cccgcattga
   551821 tcgactcttc ctttatcatc gaccggctgg gagtcgcacc cgaggttcag gccatgctcg
   551881 ttcagcagat tcgggaccac ggacaacagg tcccgatcct cgtgcggccg catccaacgg
   551941 agagcggccg ctaccaggtg gcctatggac acaggcggct tgccgccttg cgcgaaatcg
   552001 gcagcagggt caaagcggtc atccgggagc taagcgacga gcaactcgtc atctctcagg
   552061 gacaggagaa caacgcccga accgaccttt ccttcatcga gcgcgcattg ttcgcagcgc
   552121 gtctcgaaga tcgcggcttc tcgcgggata cgatcatgtc ggcgctcggc gtcgacaaag
   552181 cggcactctc caagatgatt gccgtcgtgc gccgattgcc tctggatgtc atcgaagcca
   552241 tcggcgccgc tccaggtttc gggcggaggc gctggatgga tttggctgat ctcatcgata
   552301 ccgctgaacg tcggtctaag gccctggatt tcatcggagc agccgaattc caggcgctgg
   552361 agagcgatca gcgttttgat aagctctttg cgctgctgag ccgcgccagg aaaccatcaa
   552421 aggcggaagc ctggattgcg ccggacagaa gccgcccggt ccgcattcgt gataccgatg
   552481 cggaaatgat gctcgctttc agcaagaagg cggcgccggg ctttgcggat ttcgtgaggc
   552541 agaggctcga agcgctctac ctcgaatatc aacgtgaaac aggagactga acagagcaaa
   552601 agaaaaaggc ttccgaacga ctagcgctgc ggaaaccctt ctctcgtgta gcaactagag
   552661 aatcccattt ccgcgaatca gtgtcaagca tttttgacgt cgtttcggcg aacgaatttc
   552721 ttttgccttg gaaaaggtga agaaaatgga acgtggaagt gtaacgacgc ccttcgggcg
   552781 gcgagcgatg acgcttggca tgctcgcaag tcagatcgcg gcaggtgacg taccgccgga
   552841 ccggtcggtg gacaagtgga aattattccg ttctctctgc gaagcgaaga ccgtgatcgg
   552901 tgtgtccgat cggtcgcttg cggtgttgaa tgcccttttg agcttctatc cgggctccga
   552961 gctcaccgga gaaagtggtc tcgtcgtttt tccgtccaat gcgcagctct ctctccgcac
   553021 gcacggaatg gcaggcacga ccctgcgtcg gcatcttgcg tgcctggtgg aggccggcct
   553081 gatcctgcga cgcgacagcc ctaacggcaa gcgctacgca cgacggggtc gcagcggaag
   553141 cgtgggagaa gccttcgggt tcgatctctc tccgcttgtt gtacgcgcca acgagttcag
   553201 caccgccgct gccgaacttg ctgcagcgag gcaatcgctc cgcctcatgc gcgaaaggct
   553261 gagcctttgc cggcgcgacg ccgcaaagct tctcgagctc cttcgtgaat cggccacgtc
   553321 ggtggactgg gaacagcaac aactgcgata cgaggagctt gcgacacctc tctcgcgcaa
   553381 agcttcggcc aacgatgtgg aagccgttta caatgccatg tcgaaattgc gcagcgatct
   553441 cgccaatcaa ttggagaaat tactaaattc agcaaaactg gatgccaatg atcgccataa
   553501 tgggcgtcac atacagaatt cagaaccaga ctctaaatct gaatctgaac caagcttggg
   553561 aaaaggtcgg gacacgtttt ccaccaatcc attgacctac aggatccacg gtacagcatg
   553621 cagaccaaac ccctccggga tttcggccct aactgctgat gagccaccgg ctcgcccttt
   553681 acttccacca ccgacgatct cccggcacgc cccgcaggtt ccgctgcccg ttctcctctc
   553741 ggcttgccta cagattgccg actacggacc acagggccgg atagcgacat ggaaggacct
   553801 tacgagcgcc gcggtcgtcg tcaggaccat gctgggtgtg agtaccgacg cctatgacga
   553861 tgcgtgctca gtgcttgggc cggaaaacgc cgccaccgtc gtttcctgca tgctcgaaag
   553921 ggccgaccga ataagttcgc cgggcggtta cctccgggac cttaccgcaa gagcgcgacg
   553981 gcaggccttt tcgcttggcc cgatggtcgc tgccctgagc cgcgcacgaa tgacggcagg
   554041 cacggcgctt gcgagttgat gagctcgtgc gcgcctgctc tacaacaccg tggcgtcctg
   554101 cgcagtccaa cggatcgagc gcttcgtttg aagacgatcc tctgagggcg ggtactctaa
   554161 gcctacggcg gtgtgagccc tcgattgatt tcgcaagctg aataggagaa actctcttca
   554221 gtcgcggatt cgcggcgtcg cgcgcgtttt tgccaacttg gtcgccgttt cttaagattt
   554281 ttagttctat cgtaaagcgt tggcaaaaaa ggcggcatcc ctccgatgcg gaagctatat
   554341 cggtgataat ttccgtcacg tggacgacct cagacgatgc aagttcaatc ctgcacccgc
   554401 ctctcctcta agccaaacat tgtgaaaatt catatcgcgc gatcagcagg tatcaagcca
   554461 cgtgatcgct gttgacagct gtcaacagcg cagacgctta ccggctattc gcgccaatgc
   554521 tcagcgaccc acggactggg aagaatatag tggcggaggt agcggaacgc attcttctcc
   554581 cgcctgtccg acgaaaacag gccgcgaaca tgggtcaggg gagaaaccgc cctcccctta
   554641 tagccgaact gtccgtcgat cgcatgttgc ggcagcaaac cgcgcggaaa gataaccacc
   554701 cgggcatctg ccggcagccg cggcggcagg aagtagttca agggaaatgg ccgccggcaa
   554761 tcctggcgaa aatgcaggac gaagcgccgg gggaagaatt tagctccgcc cggcgcattg
   554821 cgcgttacga agcgttgctc gaactcgtac tcgtcagcca ctttctgcgg gtcggcgcgg
   554881 aacttctcct gcaacggcat cagcttgccg acaggaaagc ggaacagcga cgtctgcccc
   554941 agacgctcca gcggcgtcgt ctggttgcgg gtcatcatca cgtcgtccgg tccgccgatt
   555001 tcaaaaaatg cgtcgagcga tccgacgacc accaggtcaa gatccaaaaa caggacgggc
   555061 cctttcagat tgccgagctt aggcccccag aggcgcgcct tgggccagat tcctttggag
   555121 tttaccggca ttctctcgac atcgagaggc ggaaggtcct cgcagagtat ttcgggccgg
   555181 aggccctcgc gattatctgt aaagcacgtg aaggtgaagg ggggcgttat gttgcgcgca
   555241 accatcgcgt agaggcgatt gatgaacggc gcaccatact ttgtgcccca gtttatacag
   555301 ataagctgtt tgactccgcc gcttgcggcg agaacctcgg atgccattgt tttcgtccat
   555361 cttttgctag cggcgcttgc gccagggcaa gccgcactgt tggcatttgc gcctgtctga
   555421 acgcgagtgg agtttgcagt tcactggagc gggatgtgga gtgcggcatt ccgctcgcat
   555481 ccggctttta acttattcca cataagttaa aagcgaaaat ctcttactat cgaagctagc
   555541 ggacgctccc agaagacggg ctgacgatgc ttccatcggc gttcgcagaa cagcggtgct
   555601 ggatagatat ggaggtgcaa cgcggttgac agctgtcaac tcagccgcct cccgcgctcg
   555661 aacgtcgggg atctggggcc gcgaacgatc ggccgatgtg caataagagt ggaaaacccc
   555721 caaatgtctg tgatggaagg gaggggcgtg ctaccttccg tcctgccgcc aatgcgttgc
   555781 ttttttaatg agatatgaat ttccagatcc gctcgacccg gcgctgctgc cggcactgat
   555841 gaccgccgaa gacgcgcttg cccggctgga cgagcggaca ggtcgtcatg cggtcgccgc
   555901 ggggttcagg gagcgcggcc agtttttcga tgcgacggct gccctttggg tggccggaga
   555961 actcgtccat gtcgaggatc tcgttctgca cgattcgcat atggatgcgc gcgcgccctc
   556021 gcacgaactg acgattgcgc atgcggtgct aagggcgagg cgacgcctgg agctggccga
   556081 tgccgattgg gcattttcaa cgtctggatt aagtgccttg agaggcgagg gaggggcggt
   556141 ccccaattat gaacctcgtg aacgctcgga tcccgagggg gaagcgaatc cgacggatgc
   556201 accggacgac ccgatggacg gttccctctc cgacgcgttc gcggagatcg atgccgcaat
   556261 cgccaggtcc gagcggctgc tggagattca cgctggaagc gtgacggagg ccgatagtgc
   556321 cgctgtcgaa ttgcagacct ctagaatgga gccgacgggc cagcttggcc tgcttttcga
   556381 cgaggaatgg gatgaggccg ctcggctgga tgcctggcgc gccgtgctgc cggtcgccga
   556441 ccaattgccc gccactcttg gggccgccgt tcttttcgat gcatgggaac gtatcgaacc
   556501 actgcgccgg cagcattggc taggctcgct cctcgtcggc gcctatctgc gccttcgcgg
   556561 caaggtagat tcgcacgtgc ttgcctacaa tactggcctg aagacaatcc gtcatgaacg
   556621 acggcgttcg aaagaccggc tgacgcgtct tgccggcttt ctggaagcca tgtctgccgc
   556681 agcagagctc ggaatgaagg agctcgatcg cctgtcgctt gccaaaacgc agatggaaat
   556741 gcggatcagg gaccgccgtt cgaacagcaa tcttccagga ctgatcgacc tcgtgctgtc
   556801 gaggccaatc gtctccggtc ctttgatcgc gcgccatctg ggtatcacgc ctcgcggcgc
   556861 gctcaatctc gtgcgcgaac ttggggtgcg agagatgacg ggcaggggac gttatcgcgg
   556921 gtggggtgtc ctctgaacgc cgaaaggccg acggtttcag ctgcgacgga gattcagctc
   556981 actcgtcact acacgcttcc cggaagccgg gtccacatcg acggtactca ggcgcattcc
   557041 gttctcgccg agcttctgca cgatgagcgt cgccttccga tcgccattga cttcccttgc
   557101 ccaggtgacg gtgagattga tcgcgttgcc gcggcgcctg cctgacagcg cggagcgccc
   557161 gcccctcggg ccgacataga tgccggtgta gcgggaaccg tcggatctca gatccgcgct
   557221 gatcgatcgc gacaccacga gcaggccacg gcaggttcct ctcatcgaga gggcggtgcc
   557281 gttcgcttgc gaatcgaagt tgcaggaaac attgatcgcc tctttgtcga ttcggagaag
   557341 caccgtgccg ccacccgtcc atcggccctc gagtgaacca agaaaggccg cctcgtcggc
   557401 gggtgcagca ttcgtctcga cgggaagcat ttcggcggaa agcacgagcc agacaagcag
   557461 gagccgaaac aattgtcgcc gcttcatcgt catggccctc ccgttagatc acgatggttt
   557521 tcgtggatca acctaagtcc ggatgaaacg gcgcaccgat ctgaaggttc cggcacgtgc
   557581 ggcaggaccg gatcctatta tcggcgctac gcgcggtgac ggccgacttc ttgccgaatg
   557641 gaacagccgc aactcaggcg aattttcttg cgccggcgac gcaggcgacg atcgcaagcg
   557701 ttgcagcgag catgccccag ctcaccgcct cccccagcaa agtcgctgcc aatgccagac
   557761 cgaagaaggg ctgcaacaat tgcaactgcc ccaccgcgac ggtcccgccc agcgcaaggc
   557821 cgcgatacca gaagatgaaa ccgacgagca tgctgaaaac cgaaacgtat ccgaaaccga
   557881 tccaggacgc cgcgctcaag tccgcaaagc ttgcaggcat ggttgcgagc atgaggaccg
   557941 tcatgagcgg aagggagagg gcaagggccc aggagatgac ctgccagccg ccgagcttcc
   558001 gagacagctt cgcgccctcc gcgtagccga gcccgcaggc aatgacggcc gcgagcatca
   558061 ggagatcccc caccggcgag gccgaaaagc cttggcggga ggcgaagccg acgactatcg
   558121 cgctgccaat gcacgagaac agccagaatg ccggtcgcgg acgctcgccg cctcggatca
   558181 cgccgaagat ggcagtcgca agcggcagaa gaccgatgaa gacgatggaa tgggcggacg
   558241 tcacgtgccg cagtgcaagc gcagtcaaca gcgggaagcc gacgacgacg ccgagcgaga
   558301 ccacgatcag cgggacgatg tcaccccgat cgggccgtcg ttcacggaag gtgaagagca
   558361 gggtgacggc aatgatacct gcgatcgtcg cccgcgctac ggtgaggaag atcggatcga
   558421 agtccatgac agccacgcgc gtagccggca gcgagccgct gaaaatcacc acgccgataa
   558481 agccgctcat ccaaccgctt gctgacttgt ccataggatg ctcctttttc cccggtatcg
   558541 ggcgggaacg ctggctcttc cagagacagt caggtacagt ttcgaagaac tgttatggag
   558601 agagagccgg tacagatgca gcggaatgcg gcgagttcgc tgggcgagag cctcattgcc
   558661 aaggtcatgg gtacggtgca gcagcggatt gcggcacgga gtttgacgcc gggttcccgg
   558721 ctcccttcca ttcgctcttt cgccttgtcg atgaaagtct caaagtccac cgtcgtcgag
   558781 gcctatgaac gccttcaggc cgaaggcctg attcgttcgc ggccgggctc cggtttttac
   558841 gtagcggcgc cgttagcgcc gctgacgctc gccgagatcg gtccgcctgt cgaccgggcc
   558901 gtcgatccct tatggatctc gcgccaggcg ctggagccgg gggagggcgt gctccggccc
   558961 ggctgcggtt ggctgtcgcc gtcctggatg ccggaggaag gattgcgacg cgccttgcgc
   559021 ggcattgccc gcgggagcag cgcgacgctc gttgattatg gtgctccgct tggattgcag
   559081 cccttgcgcc agcttctggc acggcgcgtg gcgcagcacg gcatcgaggc atcgccggac
   559141 cagatattgc tcaccgaatc cggcacgcag gcaatcgatt tgctttgccg cttcctgctg
   559201 aagcccggag atgcggtgct cgtagacgac ccctgctatt tcaattttca cgcactcctc
   559261 agggcgcatc aggcaagaat cgtcggcgtt ccatacacgc ccagcggacc ggatataggc
   559321 cgcttcgccg aagcgctcac tgagcacaag ccgcgacttt acattaccaa ttcagccctt
   559381 cacaatccga ccggcgcaac cctgtcgccg ctcgtcggcc atcgcctgct caagctcgcc
   559441 gaacaatccg ggttgacgat catcgaggat gatatcttcg ccgattttga agaagcgccc
   559501 gcgccgcgtc ttgcggcctt cgacggcctc gaacgggtgg tgcacatcgg cagcttctcg
   559561 aaaacgctct cggcggccgt tcggtgcggt ttcatcgtgg cgcctcgtga ttgggtggag
   559621 gccttgaccg acctgaagat cgcgacgtgc ttcggtgcag ccgggttctc ttcggaattg
   559681 gtgatggcgc tcttgaagga cggcagctat cgcaaacatc ttgaggcggt gcgccagcgc
   559741 ctcgctaagg cgatggccga cgttgcggaa aggctcgccc ggatcggcat cacgccctgg
   559801 atagaaccgc aggccggcat gttcctctgg tgccgcctgc cggatggcat agacgccgcc
   559861 aaactcgcaa gggaatctct cggcaaaggc atcgtgcttg caccaggcaa tgtcttcagt
   559921 cacgcacaaa cggctgccgg ctttttgcgc ttcaacgtcg cccagtcgca agacgatcgg
   559981 ctcttccggg agctcgaagc gctgatggcc cttgcatgac cggcagcccg aagagctcgg
   560041 gctgtgggtc gctgatctgt ctcacgctac cggggattga cagtggcagg atgggtaatg
   560101 ttattacgtt tgagaattgt aacgtaataa catagcgaat ttttcgaacg tcttcgcact
   560161 tgccggattg ggaatggccg gccggcacgc agaccgccgg gacggcgccg gcaaggcctc
   560221 gaatgtttgc aagtcaagaa aggaactccg atgacactgt cacttacccg ggcccacctg
   560281 atggccgcgg tagcggcaac ccttgtgttc accgccgtcg gcgcgcgcgc agacgaccat
   560341 gagacggagg aggcctggcg cctgttcgtc gccgatcaca agcagccggt cgtgcgggcg
   560401 atcgatttcg ccgacggcaa ggaactgggc cgctatgacg tgaagggata tgccgccctg
   560461 acggtcagcg cctccgggca gacggttttc gccgcgcagt cggaccagga catcgtccat
   560521 ctcatcaaga ccggaatcga cttctccgag cacggggagc accgtgatct gaaggtttcc
   560581 gacgctgcgc ttcttcccgt ggcactcgaa ggcaagcgac ccgtccatgt cgtaccgcat
   560641 gacgatcacg cgatcatttt ctacgaccgc ggcggcgtgg cggaaatcgt cgacgaagca
   560701 gcgcttctcg aaggcaagaa ggcgcaagtc aggaccgtcg atgcgacgaa gccgcatcac
   560761 ggtgttgcca tcaccatggg gcagcacgtt ctcgtctcgg tgccgaacac ggaaatcgag
   560821 ccggagccgg acaagctgcc tccgcgtatc ggcctgcgtg tcgtcgacga gaaaggcaac
   560881 caggtcggcg agatcagcga atgcacggat cttcatggtg aggcgatgtc ggcccgcctc
   560941 gtcgccttcg gctgcaagga aggggtactt gtcgcccggc ccggcggcat cgacggaccc
   561001 aagcttgaat tgctcccgta cccgtccgat ttcccgaaag gccataccgg cacgctgctc
   561061 gggggaaaag cgatgcagtt cttcctgggc aattacggtg acgacaaggt cgtcctcatc
   561121 gatccggaca gcagcgaacc ctatcgcctg atcaccctgc cgacgcggcg tgtcgatttc
   561181 ctgctggatc ctgccatccc ggccaatgcc tatattctga cggaggacgg cgatcttcat
   561241 gtgctggacg tcgtcaaggg cgagatcgtt cgtaagggca gggtgacgga gccgtacagc
   561301 aaggacggcc attggcgcga tccgcgcccg cgtcttgcgg cagcggacgg tcagatcgcg
   561361 atcaccgacc cgcggcactc gctcgtgcgc gttgtcgatg cggagacgct gaaggaaatc
   561421 cgtaccattt ccgtcgaggg tcagcccttt gcgatcgtcg ccgtcggcgg ttcgggcgcg
   561481 tcgcattgat ccaagcggcc gccgccgata cgaagccgcc gcggcggctt cgtatttcgt
   561541 gcatttaggc tggcctcagt gcaggtgcct cagcttgtcg ggattgcgca ccacatagat
   561601 agccgcgact ttgccgccct ttatatcgag ggcggtggtc tggatttcac cgtccgcctc
   561661 catcgtgatg aagccgggca gcccgttgag gaagccgacg cgcagaagct tcgagccgtt
   561721 cgcctggaaa agggcagcca gtttttcatg aactttcatt acggcatcga gcccaaggat
   561781 cggcacagtt gcggccggcc gcttgccgcc gccgtcggca tgaatgctga cgtcggccgc
   561841 aagcatcgcg ccgagcgcgt tcatgtcgcc gctgcgagag gcggtgaaga aggcctcggc
   561901 aagctcgaga ccgcgctcct tctcgacatg gaagcgaggt ctcgcctcgc ggatatgggt
   561961 gcgcgcgcgg gcggccagct ggcggcaggc ggcggtgtcg cgctggaccg tcgccgcgac
   562021 ctcttcgaag ctgagcccga acacgtcatg cagcaggaac gccgctcttt cgagagggga
   562081 aaggcgttcc agcgccaaca tcagcggcaa agtgacgtct tcttcttcct cctcttcaac
   562141 gacgggatcc ggaagccagg gaccgacata ggtttcgcgc tggcgccgcg ccgatttcag
   562201 ctggtcgagg cagagccggg taacggtgcg gcgcaggaag gcctccggct cgcgcaccgt
   562261 cgcgcggtcg gcccccatcc agcggatgaa ggcctcctgc accatgtcct cggcatcggc
   562321 cacggagccg agcatacgat aggcgacacg catcagcttc ggacgcagcg gatcgaaact
   562381 tgccgctgcc tcggcctgcg tggccggcgt catcaggcga ctgccttttc ggcgattgct
   562441 gtcgctgctg caggctcgac ccacaggccg aagccgacgg cgaggcggtt ccacccgttg
   562501 atgacattga tcatgagcgt gagcttcacc tgctcttcct gcgtgaactc tgtctccagc
   562561 gccggatagg cgtgttcatg ctcatgtccc tcggaaagcc gtgtcagagc ctccgtccag
   562621 gcgagtgctg cgcgttcgcg atcggtatag cacggggcct cgcgccacgc cgagagcagg
   562681 tagatgcgtt gctcggtctc gcccttggcc cgagcttctg ccgtatgcat gttgatgcaa
   562741 ttggcgcagc cgttgatctg cgacgcacga atcttgacaa gctcgatgag gctcggctca
   562801 aggctcgaag cgaccgcggt cgatatgctg aaccagttct tcatcagcga aggagcggct
   562861 gcaaagggat caagtctggc tgtcatggtg acgtctcctt ttcgttagtt ccgacatcat
   562921 gacgagacag gaatggctgg tgtgacatcg acgcgaaatt ttgttgcctc tgcagtcaca
   562981 gcagcctgga gaacggacat caagactgcg ttgcagagcc gatcatccta tcagccttct
   563041 ctatgtcgtg aaggaacttg ctcaggacgt ccctgcttgc ggcaagtctc tccattttat
   563101 gatccacaag gctgatctgt tcattgagcg taacgcgcag ctcgtcgcac ggctcgaata
   563161 cgggcccttc gccccgcacg cagggcagga actgcttgat ggtcgcaagc gtcattccag
   563221 cggctccaag caatctgatc cggtccacgg tccgttcgtc ggcacgcccg tattcccggt
   563281 agcctgcgga agtgcgatgc ggcgcaagga gaccttccgc ctcgtagtaa cgcagcatcc
   563341 gaatgctcac gccggtccgt cgcgacagct caccgatttt catacgcccc ccttgaccct
   563401 gacagtgctg tcagacctta aaccttgggc tcttttgtgt gaacccatca ggagcccagc
   563461 catggcagcc agtgtgaact ctttccaaat tgtccttgac ggccgtaagg cggcccctga
   563521 ggagctgaac cctttggttt tcgccggctt tgcccatttc accgccatgc aggttcgaga
   563581 cggcaaggtc aggggaatgg atcttcacct ggcgcgcctg cgggcagcct cggtggattt
   563641 cttcggggcg gctctcccgg acgaaagcct gcgctctttc atgaggatcg ccattgagga
   563701 cggctcttgc gagcaatctc tgacggtgac gattttttcg cgaagcggcg agttcacatc
   563761 ggcgggtatc ggcagcgaac cggctgcgct cgttcgaacg gggccgccct cgaaggggcc
   563821 gattggcccg ctgaggcttg cagtggtcaa tttcgaacgg ccgcttccca ctgtcaaaca
   563881 cgtcggtgag gcggccaaaa cctactacct gcatcaggcg gtccggcaag gtttcgacga
   563941 tgcggccttc gtcgaccggc gcggcagact gagcgaggcg acgatctgga atctcgtcta
   564001 ctgggacggt gaagcggtcg tctggccgga agcggcggtc ctggccggcg ttaccatggg
   564061 ggtcgtcagc cggcagctga agaggctcgg catcccgcaa cgacgggaag agatcactct
   564121 cgaaaacctc aaacacttgc agggggcggc cgtaatgaat tcctggacgc ccggcgtacc
   564181 ggtcacaacc atcggccagg tggttctgcc ggaggcgaag ccgttcatag aactgctgca
   564241 caaggcctat atagccgaac cggcgctttc tatctgacat cctgatgcgg ggcgtgccga
   564301 ccgctcaagc tccatatgcg ccgcgctgcc acaggttttc cgtggcagcg cttctcgact
   564361 acacctcaat cctcctcgac gaagacctgt tcgcgcttct tcttgacgct cggcaggaag
   564421 acaatgacga gcacggcggc ggcaaggagg agtagggttg cgctgatcgg ccgggtgacg
   564481 aaggtggacg cgtcgccgcg cgaaaggatc atggcgcgcc tgaggttttc ctcgagcagc
   564541 ggtccgagaa caaagccgag gaggagcggc gccggctcgc agcgcagctt gagcagcagg
   564601 tagcccacaa ggccgaagaa ggcgacggcg tagaggtcgt aaacgttgga attgacgctg
   564661 tagacgccga tcgaacagaa ggccatgatg attgggaaga gcacgaaata agggattgtc
   564721 aggagcttca cccaaaggcc gatcagcggt aggttgagga ccaccagcat cagattgccg
   564781 atccacatcg aggcgatgat gccccagaag agcgcgggtt gctccgtcgc gacgttcggt
   564841 cccggaacga tgccctggat gatcattgca ccgatcatca gcgccatgac ggggtttgcc
   564901 ggaatgccga gggtgagcag cggaatgaac gaggtctgcg caccggcatt attggcgctt
   564961 tccggtccgg cgacgccggc gactgcgccg cggccgaatt cctccggacg gtcggagagg
   565021 cgcttttcca ccgtgtagga cgcgaaggcg gcgagaatgg cgccgccccc cgggagcacg
   565081 ccgagcgccg agccgatcgc ggtgccgcgc agcaccggtg cgaccatctg cctgaagtct
   565141 tcccgcgtcg gcatcaagtc ggttaccttg gccataagca cttcgcgcgt tttctcgctt
   565201 tccagattgc ggaggatttc ggcgataccg aagacgccga ccgccagcgc cacgaaattg
   565261 agtccgtcgg aatattcgcg gatgcccagg gtgaagcgcg gcgtgccggt gtagatgtcg
   565321 gttccaacaa ggccgagaag aagaccgagg gccaccatgg caagcgcctt gacaaccgat
   565381 ccgtgcgcaa gcgcgatcga ggaaacgagg ccgacgatca tcagcgagaa atattcagcc
   565441 gcgccgaatt cgagcgcgat ctcggtcagc ggcggcgcga agagcgcgac gaggaatgtc
   565501 gagacggtac cggcgaagaa cgaaccgagc gccgcaatcg ccagcgccgc gccggcgcgg
   565561 cccttgcgcg ccatctggta gccgtcaatg gcggtcacgg cggaagacga ctccccgggc
   565621 atgttgatca ggatagcggt cgtcgagccg ccatattggg cgccgtaata aatcccggcg
   565681 agcatgatca acgatgagac cggttcaagc tggaaggtga tcggcagcag catcgcgatg
   565741 gtcgccgtgg ctccgatccc gggcagcacg ccgatcaggg tcccgaggag tacgccgatc
   565801 aggcagaaga aaaggttcgc cggtgagccg gcggtcgcga agccgagggc aagattgctg
   565861 aagagttcca tcgtcgcctc tgaaggactt ccaggaaaac ttgaaaaccg ttttccgacc
   565921 ggaagtgggt aattttaaaa agccaggtcg ttaccctgtg taaataaaac agggaaacgg
   565981 cctagaaccg ggtccacggg ccgaaccgct cgaagggcag gttgaggccg tagctgaaga
   566041 cggcgaccga aaagatcgtc aggccgagcg aaacggcgat cgcccagagc ggcttcatcc
   566101 ggctggaagc aaaacaggcg atcagcgccg tgacgaagat tgcggggacg aagccgaggc
   566161 cgcgtaccgt gagcccgaag aagatcggcg ccggcaggat gaagaagatc ccgcgaatgg
   566221 cgatcggtcc catcggctcg cccttgaccc gggccgattg caccaggatt gtcaggccga
   566281 gcaggatcag cacggcggat agaaccagcg ggaaataacc ggggcccatg cgcaaggcgg
   566341 tgccgagttc gagtccgaac gactgccacg caaagaaaat tccaaccgcc gtgaggatgc
   566401 cgccacacag cgcattggtc gcgtcgaagg agatggattt cattgtttcc ccgttatttc
   566461 tgcgagcgcc gattcccttc ccgaggaacc gagccgctgt tttttggcga acatcttcgc
   566521 atgtcctgct gactgatgca tatcgcccca acaccgggca accgaagcat tgcctgttga
   566581 cacctgtcaa cgcccgcgcg ggcacatcct tatgaacgcc cgcacgggtg gagatggctg
   566641 acgtgcaatc agtcggcgta ctggccggcc gcttcgatca ccggcttcca gcgggcaatc
   566701 tcgctttcca gcttcgcctt cagtgccgcc ggcgtggcgt cggcgtcgct tgacggctcg
   566761 gtgccgagtt cgccgaagcg ggcaaccacg ttctcgtcct tgagcgcttt ctgcagcgat
   566821 ttcgacaggc ggtcggtcac ttcggcaggc gtgcccttcg gtgcatagac gccgtgccag
   566881 atgccgacct ggaagccgga aagacccgct tcctcggcgg tcggcaggtc agggaagatc
   566941 ttgagccgct ccggcgaggt cacggcatag gccttgatcg tgccgccctg gatctgcttc
   567001 gtcgtgttcg tcgtctgatc gcacatgata tcgacctggc cgccgagcag gtcggtcatc
   567061 gccgggccgg tgcctttgta gggcacggtc gtcagcggcg tttcgatcgc gctcatgaac
   567121 atcatgccgc aaagatggga cgcggcgccg atgccggcat tggcgacagt caccgtgtcc
   567181 ttgttggcct tgacgtgttc gatcaggctc ttcaggtcgg tcggttcgaa gtccttgcgg
   567241 gcgacgatcg tcatcggaac ctcggtgacg aggccgacat attcgaaggc attcagcgtg
   567301 tcataggcga gcttgcgata gagcgtggcg ctggtggcca tgccgatatg atgcagaagc
   567361 agcgtatagc cgtccggctc ggcctgggcg acgcggccgg ctcccagcgt cccgccggcg
   567421 ccgccgacat tctcgacgat gatctgctga ccgagatcct tggacatgga ctcggcgacc
   567481 aggcgggcaa ccgtatcggt cgggccgccg gccgagaacg gcaccaccat ggtgatcgtg
   567541 cgctccggat aggtctgggc gctcgccgaa acggcaaaaa gagaaacggc cgcggctgcg
   567601 ctcagaagcg cgttcagaat tttcatcttt tcctcccgga tgaatagttc gacccgccgg
   567661 catggttcct cccgccggtt ctgggttcac ccattagcaa tcttgatttt aacacagaca
   567721 accgcggttc gaggcggttt catgtttttc ccgcgcgtga acgtgccaaa tgggtggatt
   567781 cggaaacaaa ggagcccgct catgggtgga tttccgcaca tcggcgcttc gcaccaccag
   567841 cctgcccgcg gcggaagccg ttccgctaga gcgggatgag gagaagtgtg cgcggtttcc
   567901 gcccgcatcc cgctttgact tattggcatc gatcacgttc atgtttccag ggtccctgaa
   567961 aacatcgtga tctaaaggcc ggttcggcgc ctgagatagc gaatctccgc ttccgccagc
   568021 ggccggcttg cccctttcgg caggtcgccg agccttacct cgccgatcgc gacgcgcagc
   568081 aggcgcaggc attcgaagcc aagtgcgtcg agcatgcggc ggatctggcg gttgcgcccc
   568141 tccgtgagct ccacctcgat ccagctgttc ctgtcgccgc cccgcaggag cgcgacccgc
   568201 gcggctctca gcagttcgcc gccctccgtt acgccctcga ccatccgcgc cgccatggcc
   568261 tcgccgagga agccacgcac ctgaacgtgg taccgtttgc cgagatgggt ttgcgggtcg
   568321 agcaggcgct gcgccagcac cgtgtcgttg gtgaagagga ggagcccctc gctcgctttg
   568381 tccagcctgc cgactggtga gagagacggg gcgtcgacgg tttcgagaca ggtgaagacg
   568441 gtcggccgac cctccggatc gtcgcgggtg gttacgagcc cccgcggctt gttcagcatc
   568501 agatagacct tcggctgcgc ggcgatgacg gtgccgtcca cggcaatcct gtccgcttcg
   568561 atatcgaccc agtgagccag atcggtaact ctcctgccgc cgacgctgac acgtccctcg
   568621 gcaatcagct tctcggcctg ggtccgagtg caatagccga gcttcgagag cgcgcgggcg
   568681 agcgtcacgc gctttcccgc tcgttctctc ccgccatcca cccgctttcc tgccgctggg
   568741 cggtgttgct tcaccggttc ggtctcctcg ctgttgaccg tgcttcatct gacataaatg
   568801 gcagtgcgag gccagagttg cctctcacga tacgggtgag ttggccggac tgcttcttcc
   568861 cttgcctgcc gatcgtcggc ggcccataaa aaacgccgac gccgcgccgg atccggccgg
   568921 cgaagtgcgg aggaactgaa tatgagcttg acgggaactt gggatttctg ggtggatcgc
   568981 ggcggcacct tcaccgacgt catcggccgc gatccgtcgg gcgccctgcg cgcattgaag
   569041 gttctttcgg aaaaccccgg tgcctatcgc gatgcggcgg tccacggcat ccggctgcat
   569101 ctcggccttg gctccggcga gccggtgccg cacggcctca tcggcgaggt caggatgggc
   569161 accaccgtgg ccaccaatgc gctgctggag cgcaagggcg agcggcttgg gctcgtcacg
   569221 acgcgcgggt tccgcgatgc gctccggatc ggctatcagg aacgcaagaa gattttcgcg
   569281 accgagatca tcaagccgga ggcactctat tctggtgtcg tggagcttga cgaacgagtg
   569341 cttgcggatg gcacggttga gctgccgctg gacgaggcgg cggcgcggcg ggcgctcgaa
   569401 agcttgaagg cggatggtta cggtgccgtc gccatcgtcc tgctgcacgc ttacaaatat
   569461 cccgctcacg agatgacggt cgcccacctc gcgcgctcga tcgggttcga gcaggtatct
   569521 gtcagtcacg aggtctcgcc gctcgtcaaa tatgtcggcc gcggcgatac gacggtgatc
   569581 gatgcctatc tttcgcccgt gctcggccgg tacgtggcac aggtttcgca agaactcgac
   569641 gtgggccgct ccggcgcccg cgtcatgttc atgatgtcgt ccggcggact gacggcggcg
   569701 gagatgttcc agggcaagga cgcaatcctt tccgggccgg cgggcggcgt cgtcggcctt
   569761 gcgcgcacgg gcgaggcggc cggcttcgac cgcgtcatcg gcttcgacat gggcggaacg
   569821 tcgacggacg tcgcccattt tgacggggag tacgagcgcg ccttcgagac cgaggttgcc
   569881 ggtgtgcggg tgcgcgcgcc gatgatgctg atccacacgg ttgctgccgg cggaggctcg
   569941 atcctccatt tcgacggggg tcgcttccgc gtgggcccgg attcggccgg cgccaatcca
   570001 ggccccgcct gctaccgcaa cggcggaccg ctcgccgtca ccgacgcaaa tgtcatgctg
   570061 ggcaagttgc tgcccgagca ttttccggcg atcttcggac cggagcagaa ccagcccctc
   570121 gacgtcgaga cggtgcgcga gcgtttcgcg gcccttgcgg ccgagatcgg cgacgggcgc
   570181 agccccgaag atgtcgctga cggtttcatc cgcattgcgg ttgcgaacat ggtcgaggcg
   570241 atcaagaaga tttcggtgag ccgcggctat gacgtgacgc gttatgcgct caactgcttt
   570301 ggcggtgccg gcgggcagca cgcctgcctc gtggccgatg cgctcggcat gaagagcata
   570361 ctcctgcatc cgatgtctgg tcttctttcg gcttacggca tgggcctcgc cgatatcaga
   570421 gccacgcggc agaaagcact gggcgtcgcg ctggacgagg cggcaccgca cgcgattctg
   570481 gagctcggtc acaaactgca atcggaatgc ctggttgaac tggaggcgca ggggatcgcc
   570541 ctggagcgga tccgcacgca tttgcgcgcc catattcgct atgccggcac cgatacggtt
   570601 ctgccggtcg aagcggcctt tcccgatcag gacgaccagg cgcggctccg ccgtgacttc
   570661 gagcatttac acaagcgccg cttcggtttc atcgccgaga acaaggctct gatgatcgat
   570721 gccgtcgaag tcgaaacggt gggtggcggg gctgcagaaa tggaggcgga gggccttgcc
   570781 gccacggccg gtgagcttgt tcccgaccag cgaatccgtt tctattcgca aggcatgttt
   570841 cacgacgcgc cggtggcgct gcgttcgcaa gtccagcccg gccagaaact cgccggtcct
   570901 gcgatcatta tcgagcccaa ccagacgatc gtggtcgaag acggctggca ggcggagttg
   570961 acgacgaagg accacatcgt gctgagacgc gtcaaggcgc tgcccgagcg taccgcgata
   571021 ggcacgaagg cagatccggt catgctggaa atcttcaaca acctcttcat gtccatcgcc
   571081 gagcagatgg gcgtgacgct gcagaacacg gcttattccg tcaacatcaa ggagcggctc
   571141 gatttctcct gtgctgtctt cgacagcggg ggcagtctgg tcgccaatgc gccgcacatg
   571201 ccggtacatc tgggctccat ggatgcctcg gttgcgactg ccatccgcga aaacccggtg
   571261 atccatccgg gcgacgtgtt cctgatcaat gcaccctaca atggcggcac gcatcttcct
   571321 gacctgacgg tttgcacgcc ggtcttcgac gatgcgggcc gcgagatccg cttctgggtc
   571381 gcaagccggg gccatcatgc ggatatcgga ggtatctcgc cgggctccat gtcgccgctc
   571441 gccaccgata tcgaagagga gggcgtctat atcgacaatt tcaggctcat cgaccgcggc
   571501 cgattctgcg aggagggact cgagaagctc ctgaccggcg cgcgttaccc ggtgcgcaat
   571561 ctccttcaga acgtcaacga tctcaaagcc caggtcgcgg ccaacgagaa gggtgtcgcg
   571621 gaactcaaaa agatgatcgc gcagttcggc gaggacgtgg tcgaggccta tatgggccac
   571681 gttcaggaca atgcggccga aagcgtgcgc cgcgtgatcg atcagttgcc ggatggcgaa
   571741 ttctgctacg agatggacca gggttgccgc atcgtcgtga aaatctccat cgatcggggg
   571801 agccgcgaag caacggtcga tttcaccgga acgtcggagc agcgcgccga caatttcaat
   571861 gcgccggagc cggtgacgcg cgccgccgtg ctctatgtct ttcgggtgct ggtagaggcc
   571921 gacatcccga tgaatgccgg ctgcctgagg cccatccgca tcgtcatccc ggacggcacc
   571981 atgctttcgc cacgctaccc ggcggcggtc gtcgccggca atgtcgaggt cagccaggcg
   572041 gtcaccaatt gtctcttcgg tgcggtcggg gcgcaggcag ccgcgcaggg aacgatgaac
   572101 aatctgacgt tcggcaatgc cgagtaccaa tattacgaga cgatatgctc cggcgcgccg
   572161 gccggtcccg gctatgacgg cgccgatgcg gtccacaccc atatgaccaa ttcacgtctg
   572221 accgacccgg agattctcga gacgcgcttc ccggtagttc ttgaagattt tcacatccgc
   572281 aaggattccg gcgggtgcgg caagtggtcg gccggcgatg gcaccgagcg aacgatccgg
   572341 gcgcgccagc ggctcgactt cgcgatcctt tccggccatc ggcgtgtccg gcccttcggg
   572401 ctgaagggcg gagagccggg cgaaccgggc cgcaactatg ttcgccgcaa tgacggtcgc
   572461 atcgaagaac tgcctggctc ggctcatacg gtgctcgaag cgggcgaggc ctttacagtg
   572521 gtgacgccga cgggcggcgg ctatgggaag gatgaggggc cggaggaagg gcagttctag
   572581 gccaaagccg agccacactt cggcacccgc tcaaagcgcg gcgaggcaac gttcgacgcg
   572641 gctccaggtg aggtgagcgg cttcggaatc gtagtccgga agcgtggcgt cggtataaag
   572701 gtgtccggcg ccggcgtagg tgaaaacctc aagatcgatc ggcgtcgttt cggcggcgct
   572761 gcgccaggcg gtgacctcat ctgccggctc gaagacatcc ggatcggcga gatggacctg
   572821 caccggcact ccagggcgtg catttgccgg aatttcggcg atgctgtgca ggaagagaac
   572881 gccggctgtc tcaggtcgct tcggccaaag gctggcagcg accgcagcgc ccatcgaaaa
   572941 gccgccgaga acggcatcgg caggcagccc ggcgaccgcc cgctcggcgc gctcgcaaag
   573001 agcgcgccaa ccgatttctt ccttgatggc aaagccctcg tcaatcgaag aggcaacccg
   573061 gccttcatag aggtcgggcg tgaagacctc gtgccctgcg actgccaacc gctcggcgac
   573121 agcccgttcg aacgggcgca gcccgtatac ggaatggaag aggatcactg tcgccatggt
   573181 cgtatcctgt ggtcgggagg cgtcacttga ccacgccgga ttgccggcgg caataggcag
   573241 ttcgtcacgc gccggagcgg cgcggccctt gcgaaatatg aattgggggg tggcggcgcc
   573301 cccgagggag gagaaagggc gccgcctgtc ggtcgactcg tctgttgtag gggagggagc
   573361 gatgagtcga ccctcttcca cgttcagtcg cttcgggcaa aagcgaccgc gtctaacgct
   573421 tcgcccggcg gatggttccg acataattgg ctgctgtcgg gcttttcagc cgcattccct
   573481 gcttgtctcg caggcgttca tcagcgccgc gtttgcggtg cttgtgacaa gcggaggaat
   573541 aaggatcgag aattattaca ggaaaggccg gattcggccg gcgcgtctca acctgttgga
   573601 ccgatgacgt tcgtgatttc agatcgattt gacctgaggt cgtcgtgatc caggcgaggg
   573661 tcgcagagcg atacagatgg ggctggggcg cgccgctctg cgaccctcgc gcgccgggat
   573721 ggcaattggg gcttgtccat tgtcccggcg cgcaaccaac gaataggcga gggcaaaacg
   573781 gcacgcaacc ttgataggac ctatggcagg ccgcatcgga ctaaggtcct acaccggaac
   573841 ggcggtcgag tatttgacgc tcttcaaggc gaaatgagac gaagaattgg cgacggcctc
   573901 atgggtgagg atacctcgca tcagcaggcg ctcatagtcg gcgacgtcag cgacgaggac
   573961 ccttaaaaga tagtcccagt cgcccgacat ggaatagcat tcgaggacct cctcatggct
   574021 ttccacgaag cgctcgaaat tgcgccgcgc cagcggatca tgagacttca tgcgcacctg
   574081 gcagaacacg ttcaatccgc gtccgaccag gtcgggatcg acgaggctta cggtcttcac
   574141 cagaacgccc gccgtctcca gggctttgat ccgccgccag caggatgccg gcgaagcgcc
   574201 gaccgcctcg gcgattgccg catggctgat gtcgccccga tcctggagaa ttcttagaat
   574261 ttttcggtcg atagcgtcga gattgaatga attcatcaca gtcgccccaa aagccgaaac
   574321 gttctcatca atccttagcc aaaaaacgac gagattgaaa ccgttttacg ctccgaacag
   574381 cgtagtctcg tatcgaagga actggaggag atccggatga cgcaggccgc acttaaaaag
   574441 gaccggcgca acgcaccgga cgagaacatc gactggaagc gtgtcgtgca gcttctgctt
   574501 ctgtcacgcg aactcgacga gatggaggaa cgacgcctcg tccccgagaa aaaggttctc
   574561 taccagtttt cggcgcgcgg ccatgacatg gcgcagattc tcctgggtct gcagctgacg
   574621 ggcaggcacg atgcggcttg cggctattac cgctcgcgcc cgctgctgct tgcactgggc
   574681 gtcgatcccg ccgacgcgct cggctcggcg atgggacgcg cgggagggta ttcagatggg
   574741 cgcgatatcg gcgtggtctt caactatccc aatccggatg gcgcctcggc gctgccaatg
   574801 tgcggcggcg tcggcagcca gtacacgccg acggccggct gggcgcaggc gattacctat
   574861 ttcaaccagg ttctcgggaa cgaggaatac cgggaggaca ttgccgtcgt cctgggcggc
   574921 gacggttcgg tcgcctcgaa cgggttctgg tcggcgctga cgatcgcgac gacgcaaggc
   574981 ttgccgctgc tcttctatat cgaagacaac ggtttcggca tttccgtccc ctcgagcttc
   575041 cagacgcccg agggcaacat tgccggcaat ctcgccggct ggaagaacct gaccgtcctc
   575101 gacggcgacg gctcggaccc ggcagaagca gcccggttga cgaaaagcgc ggtggaacgc
   575161 gtacgtgaag ggcggatgcc ggtgctgctc cggcttgagg taccccgcct cgaagggcac
   575221 agtttccagg atacccaggc ctacaagagc gaggagctcg tgaagagcga atgggcgcat
   575281 gacccgctgc cgcggctaag ggaccatctt gtgcccgcga tgttgaccgc cgaggaatgg
   575341 aacgacgcgg cgcgagccgc gaagagagag gcggagcggg cgcgcatcga ggctgaatcc
   575401 aggcccgtcg ccgatcccga gaccgtcacc ggcaacgtct ttttcgaagg gcggatgcag
   575461 atcatgggcg ggcagcactg tgccggctac tgtccgccgg aaacgacgga gagggcgaca
   575521 agcgccggtg agcggatcaa catggtgacg gcgattcgcc gcacgctaga ccacgagatg
   575581 tcggtgaacg agcgggtcgt cctctttggg gaggacatcg gcgcgaaggg cggcgttcac
   575641 gcggtgaccc tcggcctgca ggaaaaatat ggtgtcgtgc gcgtcttcga cacgtcgctt
   575701 tccgaggagg gcatcatcgg ccgggcggtc gggatggctc ttgcgggcct cgtgcccgtc
   575761 ccggaaatcc agttccgcaa atatgccgag cctgcaatcg agcagctgaa cgactgcggc
   575821 acgatccgct ggcgaaccag caatcgtttc gccgcgccga tcatcgtgcg gatggccggc
   575881 ggcttcttca aatgcggcga tccgtggcac agtcagacga atgaggtcgc cttcgttcac
   575941 cagcccggct ggaagatcgc cgttccctcc aatgccgagg atgcggtggg gctgctgcgc
   576001 accgcattgc ggggaaacga tccggtgatc tttttcgaac accgggccat gctcgatcat
   576061 ccctgggcgc ggcgacccta ccccggcgat gctttcggcc tgcctttcgg caaggcgaag
   576121 tttacgcgcg aaggcggcga catcaccatc gtcacgtggg gtgccatggt cccgcgttgc
   576181 gaagcggcgg cagagggtat ctccgccgac gtgatcgatc tgagaagcct gatgccctgg
   576241 gacagcgagg cggtcatcgc ctcagtacgc cgtacccgcc ggtgcctcat cgtccacgag
   576301 gacctcggaa cggcaggttt cggcgcggag attgccgccg tcgtcgccca ggaagccttc
   576361 atcgatctcg atgcgccgat ctcgcgcttg accatgcccg acattccgag cccccataat
   576421 cccgtcctgc tcgactgggt cgttccctcg ccggaacgga tacgcaagaa gatcaacgac
   576481 cttctggagt tctgaatcat ggtcgacctc atcgacattc aggctccttt ggagcaggag
   576541 gggacgaaag cggttgttcg caactggctc agggaaatcg gcgaaaaggt caaatcgggc
   576601 gacccgctgg tcgagcttga aacggataag gtgacccagg aggtggcggc tcctgccgac
   576661 ggggtgcttc tcgagatcct gatgcggaac ggcgacgatg ccaggcccgg cgccgttctc
   576721 ggccggatcg gcagcgagct tgccggaggc gaagatgcgc cgcattattc ccccgccgtg
   576781 cgacgggcag cggaagaata tggcttcgat cctgcgacca tcaccggcac cggccgggat
   576841 ggccgtgtta cgcgcggcga catggacagg gcgttcgcgg cgcggcaggc gggcggagca
   576901 tcgcccgagc cccggcccga cggcgggaga ggggagcccg aatccagccg gataccgcat
   576961 agcagcatgc gcgccgcaat cgccgaacat atgctcaact ccgtaatgac ggcgccgcat
   577021 gtgacggccg tattcgaggc agatttctcg gcggtgacgc gtcatcggga cgaacacagg
   577081 aagaagcttg cggcacgggg cgtcaatctt tcctacactg cctatgttgt tctggcctcg
   577141 ctggcggcga tgcgcgcggt tcccgaggtg aacagccgct ggcacgagga tgcgctcgaa
   577201 acattcgatg acatcaatat cggcgttggg atttcccttg gtggaaaggg actggtcgtc
   577261 cctgtaatcc gccgcgcgca gaatctgtcg ctggcggaga ttgcggcccg aattcaggac
   577321 ctgacgacgc gcgcgcgttc caacgcgctc tcccccgcag acgtgacggg cggcacgttc
   577381 accatttcca atcacggagt ctccggatcc ctgctcgcga cgccgatcat catcaaccag
   577441 ccgcaatcgg caatcctcgg tgtcgggaaa ctcgacaagc gggtggtcgt tcgcgaggtg
   577501 gacggcatcg atacgattca gatccggccg atggcctatg tgtcgctgac gattgaccat
   577561 cgggcactgg acggccacca cacgaatgcg tggctaacgg aattcgtccg tgtcctcgag
   577621 agctggccgg gtgaagcaac gaagaacggc ttggcctgaa aatcctcctc aaacggcgat
   577681 tgaaatcgat tacattttct ggcttcatgt gccggcagga tttgggagga tcttatgaga
   577741 aaacttatcg catttgcgct tggcaccgtc gcttccattg tgatcgcagc atccgctcac
   577801 gccgagacca tcaaaatcgg tctttcgaac ggctgggtcg gtagcgagtg gcgtacccaa
   577861 atgatagacg aggcgaaggc cgcggcggcg aaatggaagg agaagggggt cgacgtcgag
   577921 gtgtccgttc agagcgccaa tgtcgacgtg cccgggcaga tcgcgcatat ccgcaacttc
   577981 atcgctgaag gcgtcaatgc catcatcgtc aaccctaata gcccgaccgc cttcgatccg
   578041 atcttctctc aggcaaagga agccggcata ttggtgatcg ccaccgatgc ggaagtctcg
   578101 tcaccggatg cgatctacgt cggcatcgac cagaccgcct ggggtgccgc gggcggcaag
   578161 tggcttgccg agacgctcgg tggcaagggc aaggtcgtcg cgatcaacgg ggtcgccggt
   578221 catccggcga acgagatgcg cgttgcaggc tacaagagcg tcttcaagga tcaccctgac
   578281 atccaagtcg tcaatgaggt caacgccaat tgggaccagg cgcaggggca gcaggcgatg
   578341 cagaatatcc ttgccaccta tcccgacatc aacggcgtgc tggttcagga cggcatggcg
   578401 gcgggcgcct ggaaatcgat catggatgcc ggcaagacgg gccagatcgc cgcgaccggc
   578461 gagatccgca aggactttat cgacctttgg atcaagcaaa aattgaactc cggcgcgacc
   578521 gtgaacccgc cgggcgtcat ggcgagcgca ctcaacgtcg ccgttctgat gctgcagggc
   578581 aaggagctga aggagccggc gaaggccggg caatacggca atgcactcta tctgccgatc
   578641 cccttcatcg actccaagaa cctagaggaa gccgccaagc aactcgaggg caagcccggc
   578701 tattattcct atacgagttc gctttcgatc gaggaggcgg aagcgctgtt caaatgaggt
   578761 cttcggcgcg caaggcctac cgtgcggcgc gtcccggtgg gcgagcggca tgcgtcggtg
   578821 acgtcatggc tttgacgcat tcattctgcc gaatccccgt gcctgtcaca gggattcggc
   578881 agcgccgcgt tcgcggcgcg ggagagttct ttcgcccgag ggacagggcg ggattgccgt
   578941 gacgggcaca ggaatgagga tcggaggaga gcctccccaa accgaagcga acggacaaat
   579001 ctcgatgtca aagttgaaac tgagcggcgt gagcaaagct tacggcgcga ccttggcgct
   579061 acgccgcggc gacctcgagg tcatggcggg cgaggtccat gtcctcatgg gctccaacgg
   579121 ctcgggaaag agcacgctct gcaagatcat tgcgggcagc gtccggcccg atagcggcag
   579181 gatccttgtc gacgaccagc ctgtcacgat caccggaccg cgctcggcgc gggcccacgg
   579241 catcggcata ttctatcagg aactcagtct cgctgcccat cgatccgtcg gggaaaacat
   579301 ctcgcttggc aggttgccgg tcaaggcagg cgtcttcgtc gaccggtcgg aactccggca
   579361 gcgcgcagcg cgctacatcg gcctgttcga cggcgtttcg ggcgaggagt tttccgccga
   579421 ggcactcgtt ggcagtctgc gtccggacca gcgtcaactc gtcgagatca tgaaggcgct
   579481 ggccagcgag gcgccgctcc tcatcttcga cgaaccgaca tcggccctcg accgcgcgca
   579541 ggtggaacgc ttcttcgaaa tcctgcggga cctcaagcgg cgcgggcgcg gtatcgtctt
   579601 catttcgcac cgcatggacg agatcaaggc gatcggcgac cgggtcacga tcattcgtga
   579661 cggtgagacc atcaccaccc tcaatctgaa cgataccgac ccggcaacgg tcattcggct
   579721 gatggtcggg ggtgccggcg atatgccggc gtcgcaatcc tcggtgccgg cggtggtcga
   579781 tgccgagcgc ggcgccgccc tgacggtgcg caatctttcc ggccgcggct tcagcgatgt
   579841 gagtttcgag gtcgcccgcg gggagatcct gggcttcggc ggccttcatg gccaaggcca
   579901 atcggcggtg ctcaggggga tcttcggcgc cggagcggtc acctcgggca agatcctgat
   579961 aggcgaggaa agcttcgacg cgtcgggccc gcgtaaggcg atccggtgcg gttgcgccta
   580021 tgtctccggc gaccgggctc gcgacggcgt catcagcggt cgtccgatca tcgagaacgt
   580081 caccccgatt cattacctgc gcgaccggct gatgatcgcg cgaccgcgca agctccggca
   580141 caaagtggcg ccggcgctgc aaagcatgca gacgaagttc gccagcctgt ttcacccgat
   580201 cagttcgctt tcaggcggca atcagcagaa ggtgatcatt gcccgctggc tgatagaccg
   580261 cccggatgta ctgctgctcg acgaccccac caagggcatc gatctgtcgg cgaaagccga
   580321 ccttttcgcg ctgatccggc aactggcggc ggacggcctc ggcatcgtcc tctattcctc
   580381 ggaagatgcg gaactgctgg gcaacgccaa tcgaattctc gtcttcaacg gcggatcggt
   580441 cagccgggag ctcaccggcg ccgaccgcac ccgctacaac ctgtaccaag ccgcatacga
   580501 ggccgcgtaa atggcagaga ccgcaaccgt cccttcatat cggcgcgccg gcggcatagg
   580561 cagggtgctg gagcgctatc cgttcctgcc ggcactcgtc attgtcgtcg cactcctttt
   580621 tctgaacggg tttttttcgc cgaacagcct gtcctttagg gctctcaccg ggttgctcag
   580681 cacctatatg gcgctgatcc tgctttccat cgcgcagact tacgtcgtct atgccgggga
   580741 catcgacctt tccgccggcg cgatcctctc gctcgtcaat gtcgcgatcg tggtcctgat
   580801 ggagcggtgg ggagggggcg ccggggcggt gctcctcgca ctcgccatgg gtctcctgct
   580861 cggcctcgtc tgcgggctcg tgaacggcct cgtcgttgcg gccctgcggc tgcaggcgat
   580921 tgtcgcgact ttcgcgacga gtatcttttt caccggcctc gcgctctaca tcctgcccgt
   580981 tgccggtacg ccggcaccgg cgcttttctg gcgcgcctat ggtggccggt ttttcggcgt
   581041 gcctttcgtc ttctacatat tggcggtcct cgcgatcctc ctggcggtgt tgagccgcac
   581101 ccgacttgtc acgcagctgc ttgccgtcgg cgacgacccg caggcggcct accagacggg
   581161 gctgccggtg gtggcgacga gggtcaaggg ctatgtgctc tgcggccttt tctcggccct
   581221 cgcggccttc tgcatcaccg gcgatacagc aagcggcgac ccgctggtcg gcggcaagat
   581281 gacgctttac agcgtcgcgg cggtcgtact cggcggcagc gcgctttcag gcggctgggg
   581341 caccgtcgtc ggctcgctgc tcggggcgct tacgatcgcg cttgtcaact cggtcgtctt
   581401 cttcatgggc acgccgtccg agtggcagaa cttcgtgcag gggctcgcga tccttctcgt
   581461 cctgatggcc ggcgtccttg ccggcagaag ggggcgctca tgagccgtat caattcgttt
   581521 ctccgccagc cgatcgtcgt cgcgctcgtc ctgatcgtgt tcctcctcta tctcggagaa
   581581 gcgctgtcgc ctggctttgc caccggaggg cagatattgc ggctgctgat cgtcgcctcg
   581641 ctgctcggca tcatcgcggc cggccagaat gtcgtgatcc tcggcggacg cgaaggcatc
   581701 gatctgtcgg tcggcggcgt cgtctcgctc tcggcgatca ttgccggcaa tgtcatgaac
   581761 ggcgccgatg gcggcatcct gccggctgtt ggcgcctgcc tggcagcggg cgcgttcttc
   581821 ggactcctga acgggctcgg tgtcacgctt ctcagaatcc cgccgctcgt gatgacgctt
   581881 gggatgcttg gcgtgctgca ggggcttctc gtggtcatcc ggatgggcat tccctccggc
   581941 caggccgcgc ccgccctctc gcgcttcgtc acgcagccgt tcgcctacgg aatccccggc
   582001 attatctggc tctggatcat gatcggcatc gtcatggcgc tcatgctcaa ccgcaccgtc
   582061 ttcggccatc gcatctatgc gatcggctcg aatgagcacg ccgcctatat ggccggcgtg
   582121 ccggtcggca tcatccgcat tgctctcttt gtgatatccg gcatgttcgc cgcgattgcc
   582181 gggctctgcc tgctaggcta ttccggcaca tccttcgcca atgtgggcga acagtacatg
   582241 ctcccctcga tcattgcggt cgtcttcggc ggaacgtcgc ttgccggcgg caagggtggc
   582301 tataccggca ccatggccgg cgccgttctg ctggttatcc tgcaaagcat cctcacgacg
   582361 atcaatatcg aggagtcggg acggcagatg gtgttcggtg cgacgctgct ccttctcatg
   582421 atgttctacg ggcgcggccg tgcgatgcgc gcatgaaaaa ccggccgaag atcaaggaca
   582481 tcgcggaaaa ggccggggta tcggtggcaa ccgtctcgcg cgcgcttgca gattccgcgc
   582541 tggtgacggc cgagacgcgc cagcgcgttc atgacctggc gcgcgagctc gattatcgcc
   582601 cgaatgtcag cgcccgcaac ctgcgtacgc gaaagtccat ggcggtactc atggtcgtgc
   582661 gcgacgtcgg caatcccttt tatctcgaaa tcctcaaggg cgtcgaggcg acggcccgcg
   582721 aggcgggcta tgccgtgctg atgggaaata cggagaacga cccggcccgc gagaccgaat
   582781 atttcgacat gctgcgcgac ggacatgccg acggcatgat cctgatgacc ggcaagctgc
   582841 cgccctcggg gggctggacc catcttgcag tggtggtcgc gctggaaatg atcgagggct
   582901 cgggcctgcc ccatgttcag gtcgacaacg tcgccgcggc acgcggtgcc gtcgagcacc
   582961 tgatttcgct cgggcaccgg cgggttgccc atatctcggg gccggttccc gagccgatga
   583021 gcgtctatcg ccgtgagggc tatcgcctcg ccatgcgcga cgccggcctg gagatccccc
   583081 gggggtacga agcgcggggt gacttcctca tcgagagcgg cgagcgatgc tgccggtcgc
   583141 ttttctcgct ttccgatccg ccgaccgcac tcttcgtcgc caatgacgaa atggcttacg
   583201 gggccgtcca tcagctcagg aggatgggac gcgacgttcc gcgcgacgta tcggtcgtcg
   583261 gcttcgatga cctctatctg agcaaggcct tctatccgcc gctgacgaca gtcggacagc
   583321 cgcgggccga gatcggccgc accgccatgg cggtgcttct tggaatactg gcgggcgacg
   583381 gcgcttatgg aatccagccg atcgtgcttc ccacgacctt gaaggtgcgg ggaagcacgg
   583441 cgcctccacg tttctgaaaa ccagtgccgg cgaacacgcg gaacgtcgac ggccgattat
   583501 ccgggaggga agaatgtcca cattaccgaa acagaccttg cgtatcggct tcgtcggcac
   583561 gggtttcatt gcgcattttc acctgaattc gctcatcggc gtgcgcaatg tcgaggtgac
   583621 cggcgtctac agccgcagtg ccgcaaaccg cgagcgcttc gtgggcgaag ccgaggcgct
   583681 tgatctcggc aggtgtcgcg cgcatgacag ccttgaatcg ctgttctctg ccgccgacat
   583741 cgacgcgatc tggattctct cgccgaacta cacgcggctc gacgtcatgc ggacactcca
   583801 ccgcgagata aaggcgggac gcagcacgat tttcgctgtc gcctgcgaga agccgctggc
   583861 gcgcaccgtg gcggaggccc gggaaatgct gcacctggct gaggatgccg ggctcaacca
   583921 cggctatctc gaaaaccagg tgttctgcac gccggtgcta cgcggcaagg agatcatatg
   583981 gcgccgcgct gcctccacaa ccggccggcc ctatctcgcg cgcgccgcgg aagagcatgc
   584041 aggcccgcac gagccctggt tctggcaggg cgacaagcag ggcggcggag tgctttccga
   584101 catgatgtgc cacagcgtcg aggtagcgcg ccatctgctc accgcgcccg gcgcaccgcg
   584161 caattcgctg aaggtcaagt cggtgaacgg cacggttgcg aacctcaaat ggacgcgtgc
   584221 cggctatgcc gatcagttgc gccggcgctt cggcgaggat gtcgactacc gccggcgccc
   584281 gtcagaggat ttcgcccggg cgaccgtgac gcttgaggac gaggagggca atgaactgat
   584341 gatcgaggcg acgacctcct gggcctatgt gggcgccggc ctgcgcattc agctcgagct
   584401 tctcgggccg gaatacgcac tggaatacaa ctcgctcggc accgggttga aaatcttcct
   584461 gtctcgggcc gtacaaggct ccgagggcga ggacctggtg gaaaagcaga atgccgagca
   584521 gggccttatg ccggtgctgg aggacgaggc cggggtctac ggctatacgg acgaaaaccg
   584581 ccacatggtc gaaagcttcc gcaagggcgt gaagccgatc gaaacctttg acgacggcct
   584641 cgcagttgtc gagatcctta tgggcctcta ccggtctgcc gagattggtg cgacgctcca
   584701 ttttcccgcg ccggagctcg aaaactatgt tccggtcgtg gcgcgcgtgg gagcgtgagg
   584761 gtgcgtcgac gcggcggccg caccatatcg cgcgagaagt tcaccggtct tcgtcgcggc
   584821 gaagatatcg tccaacagca ggtgggcagc accgtacaga gcgctatcgt cgcgggtcgt
   584881 ggatagctct gtcgagaggt tgcgcgtggc gagcggcaga cagcgctggt agacgagttc
   584941 gcggatgccg gacagcaaca aatcgcctcc gcgtgcaagg gtaccgccgc cgccgatcag
   585001 gctcggattt atgatgctga ccacatcaga aatgacctcg ccgaccgtgc gcccggcagc
   585061 gcgcagcagc atcagggcct cgggtttccg ctgttcgacg aggtcgagca catcgcgggc
   585121 ggttccagcg ccaaagccac gggaggagag gtcgcgggcg atcgccagcc ggcggcgcgc
   585181 gcctccacgc aaccgaactt gccgcagcgg cagagcgggg cgtcattcga caggaactgg
   585241 atgtcgccga gatcgccggc agcgccctgg gcgcctcgaa acaaccttcc gccggcgatc
   585301 atgccgctgc cgatgcccgt accgacctta acgaagagca tgtcctcaac cgtggggacg
   585361 cgacgcttgt gctcgcatat cgtcatcagg ttcacgtctt tctcgacata gatcggcact
   585421 gaaaaccggg cgttgagacg accgatgatg tcgaattcgt cccagccggg caataccgat
   585481 gggccaccga cgacgcagcc gcgcttgaaa tccaccggtg tcgtcaggct gagaccgatg
   585541 ccgaggagga aaccgtgcgt cttttcgacc cctgccgcca gcgctgccaa ggcttcgccg
   585601 atctgtttca gcgtcacatc agggccgtgc attgccccgc ctttgccatc gccgtcaccc
   585661 gcgaggggaa ggcgtggttc tgctgtccgt cgccattccc gaacaggaga acggggccga
   585721 cgacgccttc gctgccggga tgctctccgg catccatgaa ggctggagcg ttgaacagtc
   585781 tctgcggctc gcccatgcaa cggcggccgc atcgctgcgc agctgcctgg cactcgcgga
   585841 caaatggggt tcccgcgacc actgagggtg cgttgagccg gtctggtggt atctgcgggc
   585901 gcgactgcaa cacgggatca gaaactctgc tcctgaagac ggcgaagccg tgacctttga
   585961 cgacgcgacg gggaaccttc gcgtcggaag gcggtttgct ccggcatgcc gaaggatgca
   586021 aatcagccga ccatactcat caccggatcg aacggtttcc tgggccaggc gatcgcacac
   586081 cgtctcaggg atcgatatcg ggtgatcggg cttgacctgt cccctccgaa ggggcggtcc
   586141 gagaccgagg agaccatcaa cctcgacatc acctccgaca cgagtgtcag ggaggcgatc
   586201 gagacggcgc gcaaacgcag tagcgggcgc atcgcttccg tcattcacct cgccgcctat
   586261 tatgacacga ccggcaagga caacccgaaa tacgatgccg tcaatgtcga gggaacgcgc
   586321 cggctgctga aggcgctgca ggaccttccc accgagcagt tcatctatgc gagcacgttg
   586381 ctggtccagg cgccgagccc cgccaaggcc acgcggatca atgagaattc gccgctcgac
   586441 cccgcctggg cctatccgaa gtcgaaggcg gagaccgagg cggtaatcgc gaaggagcgc
   586501 ggcgcgatca ggacagtgat cctccgtctc gccggggtct atgacgagga ctgccgcgcc
   586561 gccttcattg cccagcagat cgcccgcatc ttcgagcgcc gcccgaccgc ctatctgttc
   586621 agcggcgatc tcgaggcagg ccagccctat ctgcacaagg acgatctggt cgaggctttc
   586681 gtgcgcgcgg tcgaccgccg cgacgaattg ccggatgatt gcgtgttcct tatcggcgag
   586741 gaagaaacgt tctcctacgg cgaattgcag aagcgcatcg gccaactggt tcacggcgag
   586801 gactggtgca cgctctccct gcccaagagc ctggccaagc caggcgcatg gatgcagacc
   586861 gaggtgctcg accaggattc cgagatcaag ccctggatga tcgagaactc ggacgatcac
   586921 tacgagatcg acatctcccg cgcccgcagc aggctcggct ggcaaccgct gcatagtctc
   586981 ggcgcgacat tgccggagat gatacggcgg ctcaagcaag acccgaccga ctggtacgct
   587041 aagaacaagc tggaaccctc cgtggtggcg gcttcggagc ccgagatcga acaggctgag
   587101 aaaaggctgg cgcagccgct cgagcgcgga aaagcagaag tcgaagctgc cgtcgatgag
   587161 cacaggctgc gcacgctctg ggcgccgctg gcaaacgttg cgctcggcct ctggcttgtc
   587221 gcctcgccga tgacgctcgg cctcttcgat cccgtgagcg tgccggtgcc gccagccctc
   587281 ggacacgagg tcgccgaacc cgttatccgc aattcgcgtc ttgcgaccag cgagatcctg
   587341 tccggcctcc tcgtcgctgt attcgcgcta tcaggaatgt accggcgctg gtcctacctg
   587401 caatggatca cggccgcgct cggcgtctgg atcatgctcg cgccgcttgt cttctggacg
   587461 acaagtgctg cggcctatgc cgtcgacacg cttgccggca tgctgatcgt cgccttcgct
   587521 gtgatgattc cgccgacgcc gggcatcggg ctgcgggcgc tgtcggccga cgacgaccgg
   587581 ccgctaggct ggagctattc accttcctcc ttcacccagc gcatgccgat cgtcgcgctc
   587641 gcctttgtcg gcctgttcgt ctcgcgctat ctcgccgcct atcagatggg ccatgtcgat
   587701 ggactctggg acccgttctt cgggccggac gatgcgccgg tgcgcaatgg cagcgaggca
   587761 gtcgtgacgt cctgggtgtc caagggcttc ccgatcgccg atgcggggct cggcgccttt
   587821 gcctatgcgc tggatattct cgctggcgca ataggggata gccgccgctg gcgcaccatg
   587881 ccctggatgg tgctcctgtt cggcctgctg gtcgtaccgc tcggtgccgt cagcgtttcc
   587941 tttatcatca tacagccgcc gctcatcggc gcgctgtgca cgctttgtat cattcaggcg
   588001 gccgtcaccg tcgtgctgat cccctattcg atcgacgagg tgcttgccac gacccaatat
   588061 ctgtggcggg cgaccaaagc cggcgaaccc ttctggcgaa ccttctggaa gggcggtcca
   588121 gcgctttcgg aagaccagac cccgtcgcca gacctcaacc gtccggcctc cgagctgctg
   588181 aaggagttcg ttaccggcgg cgtcaacttt ccgtggacgc ttgtcgcgag cgttttgctg
   588241 ggggcagccc tgatgatcac ccccgtgttt ttcggcactt ccccgccgct ctatcacagc
   588301 gaccatgttc tcggctgtgt ggtcattctg gtggccgtca ccgccatggc cgaggtcgtt
   588361 cgtccggtgc ggttccttaa cgtgctgctc ggcgcctggg tagcctcatc gccgttcctg
   588421 ctcgatggca gcagcgcgat cggcaccttg gcggacgtcg cgatgggcct ggcgttgatc
   588481 gcactcagcc tgccgcgcgg aacgcgcagc gaagagcact acggcggatg ggaccgggcg
   588541 atcgtctgaa cgggcgggca gttttcaaga cgcggttcgg tcagctcatc tcggcaagga
   588601 ccatgacaag caggaagccg gcggcgttgg caatcgccga ggattgctgg aactgatgcg
   588661 attccgcctc gggtacgaga tcggtaatcg tcagatagaa catcccgcct gctcccatcg
   588721 cgaacagaaa accggtgacc ggctgcgcca gccccttcaa caggaaccac cctgccatgg
   588781 cggaaaggaa aagggagagg ccgataaggg aggtccatcc gagtatccgg cgcttcgcgc
   588841 tcttcggttc ctcatccagc gtcaattcac cgatgctcat gccttcgctg agattgtcaa
   588901 tacagatcgc gagaccgacg atcagtgcaa cattgggctt gaatgtcgcg ccaacgccga
   588961 tcgtcatgcc ttcgatcagt tcttccgcgc tcgttgcgcc ggcgagcacc gctacattgc
   589021 tgccgcgcgg cctgcgtcgc cggtggagac ggtcgaccgc ctctttctgg tctgcttccg
   589081 gaccggccat tttccagcga ttgacgtaga gatcgagaat gtagaccagc gcgaggccca
   589141 gcagaaatcc ggcgaccgca agtgcaagac ctgcgagctt cacggaggtg ggcatcattt
   589201 cgaaggcgaa agtgcccatg agaacgccgg ccgcaaagcc gacagcaacg gagagcacga
   589261 ggctcgacgg cctcagcgcc atggcggcca tgcccccgag cggcgatgcg acagccgccg
   589321 cggaggcaac tcccaaaatg atgaggaggt cattgctcat ggccgccggg ctctggtttt
   589381 caacgccgct ctttcaaggc ggcgcgatct gctcgaaggt acattgacgc gggtccttgt
   589441 ccgaacgcca acgcatgagt ttcgtgccgt ggcgaaagcg ccgattgccg acatggtcga
   589501 accggacctc gacgacgagt tccggtcgga ccggctccca ttcgccgctg cgctcgctgc
   589561 tccagcggct ggggccaccc ggcgctttac cggtgaagcc gggcggctcc cgtaaagcct
   589621 cgagctgacg cgtcagtgca gcacgttcct tgtccgcaat ggtcgctgta aagcccacat
   589681 ggttcagcag cccctcggcg tcatagagac caagcaggag cgaaccgacg agcggaccgt
   589741 tgctctcgta gcgatagccg ccgacaacgc aatcggccgt cctcaggcgt ttgaccttca
   589801 ccattgtccg ctcgccgcat tcgtaagcgc cgtccagtcg ctttgcgacg acaccatcag
   589861 tggcgccggc ctcccatgag gtcagccaac gcccggcttc ccggcggtcc agcgtcgaag
   589921 gcgagagctc gaccatcttc gctacggcgt tctccttgac gaaggcttcg aggcgagcgc
   589981 gccgttccct cagaggcttg ccggtcagca ccgctccgtc ggtgtcggcc agcatgtcga
   590041 agagaatcag tttggccggc gtttcaagcg acaacttctc aacccggctc gccgccggat
   590101 gcaggcgcat ctgcagggcg tcgaaggaga ggcgcccctc gattgcaatc accaactcgc
   590161 catcgagaac gaacgtcttc ggccccaacc gatgcagcag atcgagaatt tccgggaaga
   590221 agcgcccgag cggcttgccg gatttcgccc taatgtcgac gtcgctgccg gatttaaacg
   590281 cgagacagcg aaagccgtcc cactttggct cgtactgcca tgggccgccg cccggcagtt
   590341 cggccgcgga gcgagcttcc ataggggccg tgccgacggg caggggaaag ccgcccgtct
   590401 tctcagccgc cttggacaga gcggccttct tcgtcggctt tccatctgcg ggcgacgcca
   590461 tcatgcactc cgacgcagca atcggcctat ttcagcttga ccgagggctc tcgtgcccag
   590521 acgcgcagct tgccaagttc cttcaggaaa gcggctgcac tcccggcgtc ggtgagttcg
   590581 atcgttccct catcgagcaa tcccgctatg ccggccctct cgagaagggg aaccgcggcg
   590641 ctgacatagc cgatatattt gcaatgggcg aaggcgtcgg ctacgaaatc gcgcgcggtg
   590701 gcgacgtcga tcagctccgc gacggcctct gcggaggcaa gcaggaccac ggcgtcgtag
   590761 agcaccgacg ggccgccgtc gagcatctgg tgggccgcta tccgtttgcc gtctgaggcg
   590821 gtgaagccgc cgacttttgg tgcgatcagt tcgaaagccg ccttctccgt atcgaccgcc
   590881 tgcagcaagg cgttaagaag ggcggcatcc gtcccgtcgg tcgccaatat tccgagcttg
   590941 cgtccttcga aacgcttggg cccgcgctgg atgatgctga gcgccggcga cggatcgagg
   591001 tcctggcgtg tggcaacggc cgcgtcggcg ggtttcggca tcgtctccat gccgagcgcg
   591061 tggccgacct tttttcccag cgtctcgtcg atgttgagga gatgcgcgac catccgctca
   591121 cggatcaccg gcgtctcgac cttgctcagt tcgaaggtca gggcgtcggc gatgtgccgc
   591181 tgctcgggtg gcgtctggct gatgaagaac tgccgtgcct gactgtaatg gtcggcgaag
   591241 ctttcagcgc ggatgcggag cttcggtccc tgctcctccg aagcaaagtg tcggaagcct
   591301 ttgacgggcg actcgcgcgg tccctcgccc caggaattgg gctggtagtt cgcgcgcccg
   591361 acagggttgc gcatggccat gtggccgtcc tgctgaaagt tatggaaggg acatttcggc
   591421 gcgttgatcg gaaggtgggt gaaattcggg ctgccgagcc gcttcagctg ggtgtccaga
   591481 taggagaagt tgcgtccctg cagcaatgga tcgtcgctga agtcgatgcc gggcgggacg
   591541 ttctgcgtca tgaaggcgac ctgctcggtt tcggcgaaga aattctccgg catgcgatcg
   591601 agcaccagcc ggccgacagg cttcgttggc agcacctcct cggggatgat cttggttgga
   591661 tcgaggatgt cgaaatcgaa cttgtcggcg aagtcctgat cgaagagctg cacatgcagt
   591721 tcccattccg gaaagttgcc ggactggatg gcttgccaca tatcgcgccg gtggaagtcc
   591781 ggatcggcgc cgttgatctt cacggcctcg ttccagacca cggactgcag cccgagcttc
   591841 ggcttccagt ggaacttgac gaaggtggac tcgtccttgg cgttgacgaa gcggaaggtg
   591901 tgcacgccga acccttccat gaaccggaac gatcgcggaa tcgcccggtc ggacatgacc
   591961 cacatgatca tgtgcatgct ttccggtgtc aggctgatga agtcccagaa attgtcatgg
   592021 gcggactgcg cctgcggaaa ctcccggtcc ggctcgggtt ttaccgaatg tatcacgtcg
   592081 ggaaacttga tcgcatcctg gatgaagaag accggaatat tgttgccgac caggtcccaa
   592141 ttgccctcct tggtgtagat cttgaccgcg aagccacgca cgtcgcgggc gagatcgaag
   592201 gagcccttgc ttccggcgac cgtcgagaac cgcacgaagg cgggggttcg ctcgcccggg
   592261 cgctggaaca ggtccgcccg ggtgtaggcg gcaagcgact cgtaggtctc gaaaaagccg
   592321 tgaacgccat aaccgcgagc atgcacgacg cgctcgggaa ttcgttcatg gtcgaagtgg
   592381 aagatcttct cgcgaaaatg aaaatcctcg atgagcgtgg ggccacgctc gccggctcgc
   592441 aggctgttct gatcgtcggc gacagggccg ccctgcgccg tcgtcagaac gggcgtgtca
   592501 ccttcggcga tctggtgaag ctctccacca ttgccgcgtg tcgctttctg gtcatgaatg
   592561 gtggccggtt tcgtattgtt cggcgcagac ggtttcttgg ccatggcagc actccttggt
   592621 cgagggcgga tgggcacgaa accttgacgc ggaaggttgg ttccgccgca cgcgaaaatt
   592681 actccgtgat cactgcagtt atcgtgagct gatggttgcc cttaccctga cgatggggag
   592741 ctggcggtag cggcgggcgg gacctgatcg gatcggcata aaatcatgac cgttccaagc
   592801 gctgcgacgc gggatgctgg cactctcttc atcccgctct ggcaggatcg tagcggatcg
   592861 ccagcgcttc ggcgcgccag acaatgcggc gtggacggaa gcgccagtag cgttgagccc
   592921 cgtcgagagg cacgccccga ggcggaccgg aaacaagctc tgcctcgccg gtcatctgca
   592981 gaaggccacc agtcgcaaaa tccgggaaag tgagtccggc gcgcggattg accgcgatgt
   593041 tgcccagcgt gttgaagaag ttgttgcctg tgaagtccgg gatcgccagc cagccgtcgt
   593101 cgccgacatg cacgaatcca actgggccgc cccgatggga gacgtcgagc tgccggccgc
   593161 cgccgagttc ggcataggtt gcgacaaaga atgtgtctgc attctccacc agagcacgcg
   593221 cggcgtcatc gagttcgaag ctggaaacgg gcggcagggc agctggctcg gacgggtcgc
   593281 gcacgaaatg gacctgccgg agctgaatgt atttcggaca gttgccgaag ctctgttcca
   593341 cgccaaggtc gaagccgcgg ctgtgccggc gcagcttgcc gttcagtcga ttgcggcggc
   593401 gtgtgccgag atcgatgccg aggagggcga ggggggcgcc gtcctccatc ccggcttcgg
   593461 ccgggtccgc cggctcccgc ggaagctcga ccatcagcct ttttgcgtcc ggcgcgtgga
   593521 ggaaaccggg ttcccccgcc ctgagcgtcg cccaggcatc gccgttgcgg tccaccgagc
   593581 ccagcacgac catcggcaga agcgggtaga attcccggtg ctgttcgatc aggtggtcgc
   593641 gcagaacgcg ccgcccgacc tcttccatgc gcgcgtccac acccaaccgc ttctgcaggg
   593701 cgacttcgcc cccgtgccag ggtgatggtg cgaggatggt tgcctccatg tcggtgtctc
   593761 cttgggggtg atatctggcg gtgccttgct cagcatgtcc gaaccgtaaa gccgcgcgcc
   593821 cacttcgaat gtcactctcg ggtcaagccc gagaatgaaa actggagaga gggccgcggt
   593881 ctccacccga tcgcgccgca tcaaatgggg tacccgcgat gcggagaaaa gcggaagagc
   593941 tctaagccgc gagacctgcc ggggtctttt ggaactcgac gaagcccggc aaggcctcga
   594001 tgcgggcgag ccaggagcgg atttccggat aggggtgaag gtccacatcc ccttccggtg
   594061 cgcgcgccac atagctgtag agcgcgacat cggcgatcgt tggccgctcg gcggcaatcc
   594121 agcttctgcc gccgagctcc gactcgatca gctttaggat cgcatgcgag cgggggatga
   594181 cctcttccgg ccggtaagga gcctggaaaa gggtgatcag acgcgcctgg gccggaccgt
   594241 gggcgatctg gccagcagcc accgaaagcc atcgctgaac cgcggctgcc cctcctgcgt
   594301 cctccggcag ccagtccgtg cagccggcct ttttggcgag ataaaccaga atggcgttgg
   594361 aatccgggac gatcgttccg ccatcgtcaa gcaccggcag ctgaccgaag ggattgagct
   594421 tcagaaaagg ctcctgcttg tgttctttgc tggcgagatc gacgtgcacg agttcgtgct
   594481 cgagccccag aagcgagagg aacagccgga cgcggtgcgc atggccggaa agtgggtgat
   594541 gatagagctt catctggatc tcctgaatga atgagcgact gcaggatgat tgttaatcgg
   594601 ttagttgata agctccgtag tatgcattag accgtttcac caggtgaaat aatcctgcgg
   594661 agatgagcgc atggaccgct ggcaggcgat gcggattttc gtgcaggtgg ttgaaagcgg
   594721 cggtttcgcg ccggcggcga aagcgctgca tatgagcccg ccatccgtga cgcgggcggt
   594781 ggcccagctg gagggtctga tcgggacgcg gctgctgatc cgcaccaccc gttcactgaa
   594841 gatgaccgcg gcgggagaag gttatctggc tgattgccgg cgtattctcg ctgaaatcgc
   594901 cgaggcggaa gcgaatgcag cgggcagctt cacggcgccg gctggactgc tgacggtaac
   594961 ggcgccggcg ctcttcggcc gcattcatgt gctccccgtc atacttgatt ttctcgacgc
   595021 gtatccggcg atgcaggtga agaccgtctt cgtcgaccgc gtgaccaatc tggtagacga
   595081 gggtctggac gtggcaatcc ggatcgcctc actccccgcc tccggcctca tcgcccgtcg
   595141 catcggttca gtccgccagg tcctttgcgg ctcgccggac tatttcgccc gcttcggcga
   595201 gcccggtagc cctcacgagc ttgccggtca tcgcatcatc gggcgcgagg gtcttttcgg
   595261 ccattcggaa tggctcttcg gtcgcgacag cagcatccgc attccgatca gcccccgact
   595321 catctgcaac accaatgatg cggtcctatc cgccgcagtt gcggggtggg gattgtcgcg
   595381 gtttcagtcc taccaggtgg aagccgatat aagggcaggc cggctcaagg tcgcgcttgc
   595441 ggactacgag cgtgagccgg tgccgatcca tatcgtgcat gcggaaggcc gcatggtctc
   595501 ggcgcgcgtg cgcgccttcg tggatttcgc cgccggccgt tttctccgcc atgcggggct
   595561 gagcacggaa ctttgaggtc cgctatccgc cgcttccccg cacccggagc agcacgcgct
   595621 cgagcgcgtc cgtgagggcg cggtgcccgc cgccgcggtc gaaatcgatc aagacctgtt
   595681 cgttcaaccc accgggtgtc gaaaacgcgc gggagagcat gtcgagcggc gtctcgccgt
   595741 ccctgaccgc cctttgcgcg agacttgcga agagggccgc gagatacgca cgcgccttgt
   595801 cccggccgac gcctttctcg gcaaaccagc cggtcgcctg gtcgagaatg ccgagatagg
   595861 tcgccatcag ggcgcttgcg acggcaagca ggtcgtattc ctccttggtt tcgcattcga
   595921 cgggcgtgcc gagcgcttca aagatcgcgg caatatcgcg gctgggtgga aagattgccg
   595981 tcacgccctc gcgttcggcg acgaagggca aggggatcgc ctgggtgagg tcaacctcct
   596041 catcgatcca gttaaggagc ctcgtgcggt cggtcgcggc gatgacgctg acgaccgttt
   596101 gaccttttcg gaatttgagc ctcgggatca cctcctccgc aatctgcgga cgaacggcca
   596161 gaaacagcac gtcggatgcg tcgacggcct cctgattgtc cctcgcgatc cgcacgagcg
   596221 ggaagcggcc ggccagttgg gcggcgattt ccgcgttgcg cggcgagacg aggatttcgg
   596281 cgatgccgag ccccgagccg atcatgccgg tgaccatcgc ttcggtgatg gcgccggtgc
   596341 cgatgaagcc gatatgcatt caaccctcct tgattcgtcg gacgatatta atgcatgccg
   596401 cgccaagggc tacgccacgt tggatcgagc agagcaagga catctggcgt cccaaatgcg
   596461 atggaagata gatacacgtt gattgaggtt gtactaaact ccgcgtgtag tagagaatat
   596521 ttattcgtat acgtagatta gtaaataata ttatgtaaga aaaagcggct ggaaggtggt
   596581 ttagcggcag gaagacgcgc cggagttttt tgcgaaaata tatagaaaaa caacaataat
   596641 aaatgcatgt ttacatttgg tacgtcaagg agcaggatgt aaatctggat tgtaactgtc
   596701 gcatgattaa agcgtgggcc tgcatcgatc ccgctaatca accgatcaga ggggataaac
   596761 gcatgaattt cgaacagatt gtcgagcggt caaagccata tgcgatcggc cttgtcgtag
   596821 gactaattgc tgcgcccatc gtcgggttca atgcggggtg gatcacaacc accacggcca
   596881 gtcagaaggc ggtggaaact gccagggtgg atgcgctcac ggggatctgc tcaagcgccg
   596941 cagggcgaat ggcaaccgcc agcagcacgg atctggccgc gctcaagggc tatgacaatc
   597001 gtgcgaaacg cgacgagctg gtcgcagtca tcatggccga ttttcaggtt ccagaggata
   597061 tcctcgacaa gatcagcacg aactgcagcc gctcgctttc gtaaagcacg gtggacgccg
   597121 ggccttccgg cgtctcaacc aacggcaatc aggaggtcgc catgagaaat ctcattcccg
   597181 ctcgcctcta tacctacgat ttcacccgcc tatacgtatt tctcgcgttc actctggcga
   597241 ttgcggtgat tgtctatgcc gcactgttcg ggcgcattct gtagccgacc gaccatcgag
   597301 catcggctca gagtgtgccg gttcgccagt gagtctggcg cccggagact ggcgcccggc
   597361 gctcgatttt gcttccttgg gctcagcgtt tctgcttgcc accctgtggg ctgctcttcg
   597421 cggcttcctt gatctggttg gcgaagctcg tctctacctt caccggcgac ttttcctgtt
   597481 tcggcttccg cgcctcgcgg ttgcttctca cttgtccttt agccatggat tcgatccttt
   597541 acggcattga aattgatgca agccggcccg caatgagacg cgggccgagc agattcagac
   597601 atcaagcatg cgctcaaatg agacggtcgt catcaaccgt ttgaggtgca cgccgtgcgg
   597661 gctctgcgcc gggctgctta ttttcttcct tcgccgcttc gcgcacttgc ttggcactct
   597721 tgctttcgac ttccttcagc gttggctgag ggtcgggctt tctttcgaaa cggatcatcg
   597781 ttcatcctcc tggttgacag attgggagcg ctccaacaaa cgcttggtgg ctttcacccc
   597841 cgagcttcga tcagtatcct ctcccgccca tcgcgccgtt tccggcattt tgagcggcgt
   597901 ttttctctgg gatatcggcg accatggctt cggcggtgat caggagtgcg gcaatcgagc
   597961 cggcgtcccg caaggctgtc cgcacgacct tggcgggatc gacgatcccg gccttgatca
   598021 tatccacata ggtttccgtc tgcgcatcga agccctggtt ctggtcgctg ctgtcgacga
   598081 gttttccgat gacgatcgag ccttcgacgc cggcattgtc ggcgatctgc cggattggtg
   598141 cctccagtgc cttgcgcacg atcgcgatgc ctgcggtaat ctcggggttc tcgccggtga
   598201 gactggcaag cgccgatttc gcacgcaaca acgccacgcc gccgccggca acgatgcctt
   598261 cctcgactgc cgcgcgggtg gcgttcaggg catcgtcgat gcggtccttc ttttccttga
   598321 cttcaagctc ggtcgcgccg ccgacgcgaa ttaccgcgac gccgccggtg agcttcgcca
   598381 gccgctcctg cagcttctcc ttgtcgtagt cggatgtcgt ctcttcgatc tgcgccttga
   598441 tctggctgat gcatgcctgg atggaggcct tatccccgga gccgtcgatg atcgtggtcg
   598501 tgtctttctc gatcagcacc cgcctggcgc ggccaagcat atcgagcgta acgttttcga
   598561 gcttgatgcc gatatcttcg gaaatcatct ggccggcggt cagaacggca atgtcctgca
   598621 gcatggcctt gcggcggtcg ccgaagcccg gcgacttcac ggcggcgatc ttcagacctc
   598681 cccgcaactt gttgacgacg agcgtcgtca acgcttcgcc ttccacgtct tcggagatga
   598741 tgagcaaagg cttgccgctc tgcactacgg cctcaaggat cggcagcatg gtctgcaggt
   598801 tgccgagctt cttctcgtga atgaggatgt agggatcgtc cagttccacg cgcatcttct
   598861 cggcattggt cacgaagtac ggcgatagat atccgcggtc gaactgcatg ccttcgacga
   598921 cgtcgagttc ggtatcggcg gtcctggctt cttcgacggt aatgacaccc tcgttgccga
   598981 ccttctccat cgcccctgcg atcatctcgc cgacgctggc gtcgccattg gcggcgatcg
   599041 tgccgacctg tgctatctcg ctcgacgaat tgaccttcgt ggcgcgcagc ttgatttccg
   599101 cgaggaccgc ggtaacggcg aggtcgatac cgcgcttaag atccatcggg ttcatgcccg
   599161 ccgcgaccag cttggcgcct tcgcggaaga tggacgcggc aagcacagtc gccgtcgtgg
   599221 tgccgtcgcc ggcaagatca ttggtctttg atgccacttc gcgcaccatc tgcgcgccca
   599281 tgttctcgaa cttgtcttca agctcgattt ccttggcgac ggagacgccg tccttggtga
   599341 ttcgtggtgc gccatacgac ctgtcgatga cgacgttgcg gcccttcggg ccgagcgtca
   599401 ccttgacggc attgttgagc aattccacgc cgcgaagcag gcgatcgcgg acttcggtgg
   599461 agaagatgat ttctttggcg gacattgtct ttgaccagtt cgggcttgag atatggaaaa
   599521 ggaattcggc gagtcaggcg acattggcgg cggtcgccat ggtcttctcg acgatgccca
   599581 ttatgtcggc ttccttcatg ataagcaggt cttcgccagc gatcttgacc tctgttccgg
   599641 accatttgct gaacaggtcg tatcgccggc cttgacgtcg agcgggatca gctttccgct
   599701 ttcgtcgcgg gagccgggac cgacggcgat cacttcgccc tgctggggct tttccttggc
   599761 ggtgtcggga atgatgatcc cgcccttgga tttggtgtca ccttccgcgc gtcggatgac
   599821 gacgcggtcg tggagagggc ggaatgtcat tgaaatcttt ctgcggcccg cgcgtagggc
   599881 ggctgcaact tttaaatagc atcgaaagca ctcgattgat aggagtgcca gaaaatatta
   599941 ttggaaaata aatagcacgc cgaaataata ttggagtgtt ttgcgacgac actgacagca
   600001 cgacaattgg ctcgtcggat gtccagcgcg ttacgacatc ggctgcgcag caaacggcgt
   600061 tccagcatat atttcttccg cacgaaagca ttgcataccg cctgctctac cgcagccgtt
   600121 ttccctctcc atcgaacacc agcgccgagg ccggatcgaa acgggcagcg aggcggtcgc
   600181 cggcctttag tccgcggccg ttcttcgttt cgacgacgat caacgcgcca ttgccatggc
   600241 gggcataggc aaaggtctcg ccgccgagat gctccagcat gtcgatggtg agatcgagca
   600301 cagccggtcc ggcttcattg aagtgctcgg gccgaaggcc gatcgtcacc ggagtatccg
   600361 gggctatcgc ttcgaggctt atcggaattt tcaagcctcc gtggtccggc aggcgcgcat
   600421 aagtccggcc ttcgacgatc tcggtcgttc ccttcaggaa attcatcttt ggcgagccaa
   600481 tgaagccggc gacgaagagg ttggccggat catcatagag attcaggggc gagccgatct
   600541 gctcgaccac gccgccgcgc atgacgacga tcttgtcggc gagcgtcatg gcctcgacct
   600601 gatcgtgcgt cacgtagacg atggtggtgg cgagctgctt gtgcagtcgc gcgatctcga
   600661 tgcgcatgtg cacgcgcagt tccgcatcca ggttcgaaag cggctcgtcg aagagaaaga
   600721 tcttcggatg gcggacgatc gcccggccga tcgccacgcg ctggcgctgg ccgccggaaa
   600781 gctgcttagg cttgcggtcg agcagcgtcc cgagttcgag gatatcggcg gcttcgttca
   600841 cccgcttctc gatttcggcc ttggggacgc cggcgaagcg gagcgcgaag cccatattct
   600901 cgcggaccgt catgtgcgga tagagcgcat aggactggaa caccatggcg ataccgcgtt
   600961 tggacggatc gacgtcgttc atcctgacct catcgatcga aagctcgccc gaagtgatct
   601021 cctcaaggcc tgcgatcatc cgcagaaggg tcgacttgcc gcagccggac ggcccgacga
   601081 agacgacgaa ctcgccggat tttatgtcga gatcgacgcc cttgatgacc tccaggccac
   601141 cataggattt acgaacctgg ctgagttgga gattgctcat gcgttccact ctccttccgc
   601201 catggcgacg agctcgagct tcaccccgcc gagacgcgac gaaaccgcgg taacgacgat
   601261 ggcgccggcg gctcccgtcg actccagcca gaagccggtg gagccgcctt ggaagacgag
   601321 gcgcgtagga ccgacgaccc gcgccggacc atgcacctcg atagccacgg catcgttcag
   601381 gaagggcagg acgttgccgg cctggtcgag cgcgcgcagc atgatgcgga tgctgtcgcg
   601441 gcctccggcg cgaagcgtct ttccgtccgc ctcgatctcg agtgtcgtcg gaacggggtc
   601501 ggcgaccatg cggcgaccgg cgaccggctt gccgtcgatg aagccggtaa attcagcgct
   601561 ttcccacttc atgccccaga cgccgagctc gtccttggtg aagtgacggt gatcgatcac
   601621 gacgggcggg tgcggcaaat gaggatagtt ttcccggtcc gggccgatac gctttacgag
   601681 cgaaccgtat ttcagttcca cctcatcgca attcgtcagc acgatcaggg ggaggacgcc
   601741 acctatattg cgctcgccgc gcgcccagaa agtgacgggc ttcatcacca cttcttcgga
   601801 cggatcgcat tggctggcat agacataggc tgcgaatttc ggttcacgga acatgtccat
   601861 gacgccgtga tagcagatgc ggtcgccgga gccgaaatcc ttatgagtgt tgtagtcgaa
   601921 catgcaccag ccgatcgcgc cggaaatgct cggatcgcca taggcggcgt tcagcacctc
   601981 cagatgccgt cgcacgtgtt cggcctgccg ctgctcctga tcgtagatct tcgtcggata
   602041 catatggccg ccgaactcgg tgatgagata gggcacctta cgggaaagcc cggtgcattc
   602101 ctgctgcggg cggagcgccg tgcgcgggcg gttcgagccc ggcagttcct cgttgccgag
   602161 gatgaagtcg ttcatcgtgt agacatcttc cagaaactcg ctgtcggtga tgtaacgaac
   602221 gccgccggtc tgccgcgtcg gatcgagctc gcgcgcaagc cggttggtct tcgcgtagaa
   602281 gtcgtgggaa tcctgtgact cgttgatgcg cacgccccag atgacgatcg agggatggtt
   602341 ccagtcacgc tcgatcatgc gggccacgtt caggatcgcc tcctctttcc aggcctcgcc
   602401 gcctatatgc tgccagcctg gaatttcctc gaagacgagc aggccaattc ggtcgcaatg
   602461 gtcgaggaac cacttcgact gcgggtagtg cgacgtgcgg acgaggttgc aatgaagggt
   602521 gtgcttcatg atttccgcgt cgcgctcctg ggcggtgcgc cccattgcgt agccgacata
   602581 ggggaaggac tgatgacggt tgaggccgcg gatcttcagc agacggccgt tgagccgaaa
   602641 gccttcgttc gtgaactccg cggtgcggaa accgaaatgc gcggcgacgc ggtcggaccc
   602701 tcggccggtc ctgagttcga cttcgacctc atagagcacc ggatcgtcga tgtcccagag
   602761 ggagaggcct ttgaggccgt ccatctggac ggtgacgcca ccaccagccg tctcgccagc
   602821 cacctctgcc agcacatcgc cggcggcatc cttgaggagt gccgatacgg ccccggtgaa
   602881 ggaaaggcct tgcggattgg ctaggtcgca acggacggag acggtcctgg catcggagag
   602941 cacgtcgcgg gtctcgatct tgatattggc gatcgaaacg ggatccgtga tcttgagcca
   603001 gacgtcgcga tagatacctg caaaggtgag ataatcgatc cggccgccga acggcggtat
   603061 ctccgggttc tcactaccgt cgatctttac ggtgatgaga ttgtcgccct cccgaagcct
   603121 gccggtcagg cgcgcctcga tcggcgtata gccgtccttg tgcgcgacga tctcttcgcc
   603181 gttaagatac acgaccgcat cggccatcgc cgcgtcgaag acgagcgaga cttcgcggcc
   603241 ggagaagtcg ggccgccagg cgaggacctt ttgataggtg aaggcgcgct ggtagcatgt
   603301 ctcgtcaaaa tagttgaacg gcagttcgat ggcgttgtgc ggaagtctga tcggctgccc
   603361 cgcctggagc gtaccggcgt ccgccgcagt gaagcccgcg gagaagaccc acgaatcgtt
   603421 gaaggaagta acagagcgca tcatcgttcc tatttgactg agcccagcat gccctggacg
   603481 aactggcgtt gcatgaagaa gaagacggca agcgtcggca gcgttgcgag gatcgtgcca
   603541 accatgacga cgccgtaatc ggggtagtag gcggaggcga gtgaggaaat gaccagcgtg
   603601 atcgtctttg tctcgttcgt ctggagcacg atcagtggcc agagatagtt gttccaggcg
   603661 gtcatgaaga cgatgacgaa ggcagccgca taggtcgatc gcatgaccgg cacgtagatg
   603721 aagaggaaaa tttgccattc cttaagcccg tccacctttg ccgcgtcgcg cagttccgac
   603781 gggaaggcct tggtgctctg ccggaaatag aaaatgacga aggccgaacc gatcgagggc
   603841 aggacgacgg cgatatgcgt gttgatgaga cccgccttgc ccatgatgac gaagagcggg
   603901 atcatcagcg cagcgaaggg gatcatcagc gtgagcagca tcgcccgata gacgcgctcg
   603961 cggcctcgcg agcggaacat ctcgaagccg tagccggcaa gcgaggagac cgcgagcgtg
   604021 agcacggttg caaggatggc gatctttgcg gaattccaga agacgagcgg tacgttcagc
   604081 gtgaagaaat tgccgacatt ggttgcaaag gctgcgcccg gcaggagctt tcccttgatg
   604141 atatcgatcg acgaattggt tgctcccagc accatccaga taaaggggaa gatggacaga
   604201 aaggccatca ggccgagaaa gccataggtg gcggcgcttg ccgcgaagcg tccaattccg
   604261 ttcatctgtc gcgttccctt gctgcgaaga actgcacgaa ggcgaggagc gcgacgagga
   604321 cgacgatgac ataggagacc gtcgccgcat aacccaggtt cggcatgaat cggaaggtca
   604381 gattgtagat gtacagcgac agcgtgagcg tggcgttcga cgggccgccc ttgccctccg
   604441 tcagattgta gacctcgtcg aaaagctgca gcgtgccgat cgtcgaaatg atggtggtga
   604501 agagaatgac cggcttcagg agcgggatgg tcaggtgcgt gaagcgggcc caggccggca
   604561 caccgtcgat ccgcgccacc tcgtagatcg acttgtcgat gttttgaagg gcggcgagat
   604621 agaagatcat gttgtagccg gtccagcgcc acgtgatggc cagaatgacg agcaccttcg
   604681 cccagaaggg atgcgtcagc cacggaatgg gcgaggcgac cagaccgatc gcctggagcg
   604741 tcgaattgac gatgccgtcg gttgcgaaca tgcccttgaa gagcaccgaa taggcgacca
   604801 gtgaactgac gcaggggagg aagatcgccg tacggaaaag cccccggccg acgagtcgag
   604861 gattgttgag gagagacgcc aggatcagcg cgagcaggat catgatgggc acctgcacga
   604921 cgaaataggt catcgtgttg gtgagtgcct tgatgaagac cgggtcgttc cacagacgga
   604981 cgatgtttgc gaagccggcg aatttcatgg tcatgccgcg gccggactgg aacgacatcc
   605041 agagcgacca tgcgatggga tagatcatga aaagggcgat cagcccaagg gccggtgcaa
   605101 cgaacagcca gccattgacg tcataatacc ggccgatgcc ggcacggcgt acgagtgcca
   605161 tcgtcaacct caccaaggga gtagcagggg atactggccg tgactggatc aagtcacggc
   605221 cgggttcgcg gaagtcgccc tcgcgattac tggatctggc cggcgatctc ggcctcgatc
   605281 gccttcagca cttcgtcgac gggcgttccc tgggtgacgg ctgggagctg cgcggtaacg
   605341 gcgagatccg cctcattggt gaagatgccg taattgaccg agggaacctt cgccagccat
   605401 tcggagaagt tctgccagac cttctcgccg ccgaagaagg ggtctgcggc ctcgtaggcc
   605461 gcgccgccgc gggcagcgag cagcgagccg accgcgccgc gatcctggag tatcttctga
   605521 tagaaatcga tgtccttggc atagatctcg ttcaggaaat cgatcgcttc tgccttctcc
   605581 tcggagcttt cgagcacgta ccagctggag ccgccgagat tggaggcatg cgtggcgcct
   605641 tcgatagaga gcgccggtat gggggcgacg ccccagttgc cggactggtc cggttgcgcc
   605701 ttgacggtgc cggtgatcca gacgccggtg acgacggtcg cgacatcgcc ggaggtgaag
   605761 gtaccgaccc agtcggacca gccgttggca ggcttgtaga tattggcctg catgatcttg
   605821 ccgatggttt cgagggctgc cttcagcgcc gcgttgccgg tgatgttcgg cttgccttcc
   605881 ttgtcgaaat accattgccc ggccgactgc atgatgatgc ggacgaggcc ggcgtcgttg
   605941 ggatcgaggc ccatcatctt cttgccggtc tttgcctcga cctgcttgcc gatctcgatg
   606001 aaacgatccc aggtgagatc ctgcatgtcc tccggcttga agcctgcggc ttcgagataa
   606061 tccttgcggt aatagagccc ggtgacgccg gaatcgaagg gcattccgta gacttcacca
   606121 tcgagggtca tcagctcgac cttgtagggg gcgaaaccgg agtaatcgac ggtgccggag
   606181 agcggcgcaa aggcgcccgg aaaggattgc aggtatttct gcgcgccgta atcctcgatg
   606241 agaacgatgt cgggaagcgc gtcggcggtg ccggaggaaa ggccggtctg cagcttctgc
   606301 tcgacgtcga gcttggcgaa gtcgacgatg ttgaaggtga cgtctggatg cgtcttcgtg
   606361 tagcggtcgc ccgcctcctt catgatcgcg acgttgaagt tcgggtccca gcaccagatg
   606421 gtgatttcct tggcctgcgc cgcagacacg cccagaaagc tcgcgcctgc gagagcgaga
   606481 gcagcgatac gcggcagata ggcacgcgcc tgaatgtcca ttgtttcctc ccgaaattgt
   606541 gttccctgag acagtcctct ctgtctcgag cgggaagtat ttcccaaaac gcaaggcgat
   606601 gcaatatttt cagtaaattt ttacttgccg cggttttttt caaagggctt accgccttgg
   606661 gtgggggcgt tcgcggcaac agccagagtg aacggagggc gcttgggaac gcgcaacctg
   606721 gcggattttg ccacgaccgg gcttgagttg atttcaccct gggacttctg aggcggaact
   606781 tgcgggcacc atatgctctg ccgggtttgc agccccggtt ggtgccggtg tgcttgcgcg
   606841 ccagatgatt tcggtaccaa agaccacctt cttggcgacc tcgcggccgg acaggcgttc
   606901 gaccagcagg tcgacggcgg tttcgccgat cagttccgcc gggatcttaa ccgtggaaag
   606961 cggcggcccg agaaactgcg cgaccggaat gtcgttgaag cttgcgactg cgacatcatc
   607021 aggaatcctg agccccatct cgttgatcgc cctataggcg ccgagcgcca tattgtcgtt
   607081 gcaggtgatg aggatcttcg gcggattggg cttcgacagc atcgccttgg caagcctgta
   607141 gccgctgtcc ggagtcatcg gatcgaccag gcacaattcc ggatcaaaga gcccggtttt
   607201 ggtcatccag tcgatatagg tgtggcagcg acgctccgaa tgaatgttgt ccggcccgta
   607261 gaaagcgtcg atccaaccga tgaatccgat gcggcgatag cccatggcat gcaccgcctc
   607321 caggagccgg atcatcgcct gggagacgtc gctgagtacc gtgtcttcca tgtctccggc
   607381 gggcgcataa tcggcaaaca cgagatggcg gctgtggcgg cgcagccatt cgagctcgtc
   607441 gccgtaatag tgaccgacgg ccaccacgcc cgaggcgcct tcaaggatcg tcgcttcagg
   607501 agtgttgccg gtgagaaaga ccttgaccac atcgctgttc agggcctgac agcggctttc
   607561 gatgccgagc cggacgccga cataataggg gtcggcgagt tcctgggccg ggtctaggaa
   607621 gtgcacgagc gcgatcttca atccgctgcc gactgcctga gccgcggcac ggttgcggtt
   607681 gcgcggcgtc gcatagttca aagcctcggc cgtttcgatg atcgcctggc gtttcctggt
   607741 ggaaatggac agtgtcggat catagttgag cacccgggag acggttgctg acgacacgcc
   607801 gacggccgat gcgatttcct tgattgtgac cattcagttc cgtcccgtcc gtctgccata
   607861 ccgcgctgga gtatgtttag taaattttta ttgtggtttt atcaaccgcg agcgagcttg
   607921 ctcacggatg cgtcgactcc gcctgggcgg cctgtcgcag gcacgctcgc atacatgccg
   607981 gtggtgcgga actcggtcgg gctcgcaccg aaaacgcggc ggaagacctt ggcgaaatag
   608041 ttgggatctt cgaagccgga caggatggcg acctccttga ccggcagatc cgcggtcttg
   608101 gtcagcagct tcactgctct ttgcaggcgc ttctgcagca cgaattccgc cggcggcatg
   608161 ccttcgctcg cggcgaagac gcgggagaaa tgggcacggc tcaaacctga gatgcccgcg
   608221 agttcctcga cgggaagcgg cttgtcgagg ttgcttagga tatgatcgat cacgtgctgc
   608281 atcttgcggt attcgtcact caggaccgga tgcgatccga agacatcgtc atagagggcc
   608341 atcgccgcct cataggcgat cgccgaggcg ctccccgggg tctcgccgcc ggtgatgagg
   608401 cgcaggctgc agtcagccag gtgttcgatg gtttccggct gcagcttgag caccggaccg
   608461 gtgacggcga gaatcgcgcg gtggatgcgc agcgcctctt cgccgttcat ggaaatccag
   608521 aagaactccc atcgcccgcc gtcctccagc cagtagcgat ggttgtgggg gacgagcagg
   608581 agcagcgtct cacccgggct cacgcggaag ctgcggcttt cgtaacgcag attgccggcc
   608641 ccgccgatcg tgtgctgcag gacggtgaag ggcgtctggc cgcgcttgcg cccgtcccaa
   608701 tcgtagctcg cgtcagtcct gatctcatag ccggtactgg tcggcatcgt atgcaggctt
   608761 tggcgtccgc gcggcagaga aacggtccgc attgccggtc cacgatccat cagatgccgc
   608821 agcacagaat tacccatgaa agcacaatac ctctctagtc gcgcattcga ttatacacat
   608881 aatgcccacg gacgacgcaa gacatgcatg tatcgtggcg ttgacgcggg cttggagaga
   608941 aggacgcctc atcgctggtt cagaccggat caatgaaccg attttaccct tttagcgcga
   609001 ttggcgcagc ctgaggagga atagcagggc catggcaagc ttcaagatcg ccattatcgg
   609061 cgccggcagc atcggcttca ccaagaagct cttcacggac attctttccg tgccggagct
   609121 tcgcgacgtc gagtttgccc tgacggatct gagcgagcac aacctcgcga tgatcaagtc
   609181 tatcctcgac cggattgtgg aggccaacaa actccccacc cgggtgacgg caaccaccga
   609241 ccgccgcagg gcacttgagg gcgcgcgcta tatcatcagc tgcgtgcgtg tcggcggcct
   609301 cgaagcctat gccgacgata tccggatacc gttgaaatat ggcgtcgatc aatgcgtcgg
   609361 cgacacgatc tgtgctggcg gcattcttta tggccagcgc aacattccgg tgatcctcga
   609421 tttctgcaag gacatccgcg aggtggcaga gcccggcgcg aagttcctga actatgccaa
   609481 tccgatggcg atgaacagct gggcggcgat cgaatacggc aaggtcgaca cggtcgggct
   609541 ctgccatggc gtccagcacg gagccgagca gatcgcggag attctcggcg ccggggaggg
   609601 tgagctcgac tacatctgct ccggcatcaa ccaccagacc tggttcgtgg atattcgcct
   609661 tggcggccgc aaaatcggca aggacgaact cgtcgccgcc ttcgaagcgc atccgatttt
   609721 ctcgcagcag gagaagctcc gcatcgacgt gttgaagcgt ttcggcgtct attcaaccga
   609781 aagcaacggc catctttcgg aatacctccc ctggtaccgc aagcgtcccg acgagatttc
   609841 gagatggatc gacatgtcgg attggatcca cggcgagacc ggcggatatc tccgctattc
   609901 gaccgagacc cgcaactggt tcgaaacgga atacccgcgc ttcctcgaag aggcgagccg
   609961 gccgctggag acgatcaagc gctcgaacga acatgcaagc cgcattctgg aagcactcga
   610021 gacgggacgc gtctatcgcg gccacttcaa tgtcaagaac aacggcgtaa tcaccaacct
   610081 cccggcggat gcgataatcg agtctccggg cttcgtcgac cgcttcggca tcaatatggt
   610141 ggcgggcatc accttgccgg aggcctgcgc ggccacctgc attgcctcga tcaacgtcca
   610201 gcgcatgtcg gttcatgcgg caatcacggg cgacatcgat ctcctgaagc tcgccgttct
   610261 gcacgacccg ctggtcggcg ctatctgcac gccggaggag gtctggcaaa tggtggatga
   610321 aatggtcgtc gcccaggccg aatggctgcc gcaatatgcc catgcgatcg acgcggccaa
   610381 ggaaaggctc gcccgcgcca ccgtcgctac gcgggagtgg aagggtgcag cgcgccgcga
   610441 ggtgcgctcg atcgaggaaa tccgcgcgga aaaggaagcg gcgaagctgc gtgccgccgg
   610501 gtaggtctat cccggcctgc gagctgcctc tcatccggcc tggcgccacc ttcttcccgc
   610561 atgcggggag agggctgggg tgaggggcaa tcgcagccac tggggttcac cacttggcgt
   610621 tggaatgact gcgcaatgaa gacatgcagt aggaggagcg ccagccgccc cggcgtggcg
   610681 aagacaggag ggagaacctg ggacaatgaa aacacatcga tcgaatagaa cggcgtacct
   610741 gctgatcggc atatccgcat ttgccgtgca ggccttcgca tcagagccta cgatcgtgcc
   610801 cgaacagccg ccattcccgg cgcagggcaa aatcacctat gtatcccgcg aatccattct
   610861 cgagttcaag gcgctgcccg agtacaggga gcccgaatgg gtcacggaga aattcgtcaa
   610921 ggccggcaag ctgccgccgc tatccgagcg cctgccgaaa gaaccgatgg tcttcaaagc
   610981 aggcaacatg ccggacggaa tgggcgtcta tggcgatgtt atgcgccatg tgatcggcgg
   611041 ccggccggaa ggctggaact acagtgccgg ccagacccag ggatggggcg gcatcgacat
   611101 tggaatgttc gagtgcctga cccgcaccgc accgcttttc caggttgagg cggacgacat
   611161 ggagccgctg ccgaacctgg cgaagagctg ggaatggtcc gaggacggcc acaagctcac
   611221 catgcatctg atcgagggcg cgaaatggtc ggacggcgat cccttcgacg ccgaagacgt
   611281 catgttctat tgggaggaca atgtcctcga tccgagcgtt tcgccattga acggcgcgac
   611341 gcccgagacc ttcggcgagg gaacgacgct gaaagaggtc gataaataca cggtcgaatg
   611401 gaccttcaag gaggccttcc cgcgtcagca tcttttcgca atggcctatg gcaccttctg
   611461 ccccggcccg tcgcacatcc tcaagaccaa gcacccgaaa tatgcaggca cgacctataa
   611521 cgaatacaag aacggcttcc cggccgaata tctgaatctg ccggtgatgg gcggatgggt
   611581 accggtcgcc taccgcccgg atgatatcat cgtgctgcgc cgcaacccct attactggaa
   611641 ggtcgacgag gccggaaacc agctgcccta cctcaatgag cttcactaca agctctcgac
   611701 ctgggccgac cgagacgtgc aggcaatcgc cggatcgggg gacttctcga atctggagca
   611761 gccggaaaac ttcgttgaat cgctgaagcg agccgccaat gagagcgcgc cggcacggct
   611821 tgccttcggt ccgcgcgtca tcggctacaa catgcacatg aacttctccg gcaatggttg
   611881 gggagatccc gatgaacgcg ccaaggaggt gcgtgagctg aatcgcagcc tcgacttccg
   611941 caaggcggtc accatggcgg tcgaccgcaa gaagctgggg gaagcgctgg taaaaggtcc
   612001 cttcacggcg atctatccgg gcgggctttc ctccggtacg agcttctacg accggaactc
   612061 caccatgtac tacccccacg atctcgaagg tgcgaaggcc cttcttgaaa aggttggact
   612121 gaaggacacc gacggcaacg gcttcgtcaa ttttccggcc gacaaacttg gcggccgcga
   612181 cgtcgaaatc gtgttgctcg tcaattccga ctacagcacc gaccgaaatc ttgccgaagg
   612241 catcgtcgga cagatggaaa agctcgggct ccggatcgtt ctgaatgcgc tcgacggcaa
   612301 gcagcgggac gcggcaaatt atgcgggccg cttcgattgg atgattcata gaaacacggc
   612361 ggaattcgct tccgttgtgc agaacacgcc tcagctcgcc ccgaccggcc cgcgcaccag
   612421 ctggcatcac cgcgctccgg aaggcggcga ggtcgacgcc ttgccccacg agacggagct
   612481 cgtcgacatc gtcaacaagt tcatcgccag caacgacaat gacgagcgcg cagagctgat
   612541 gaagcagtac cagaaggtgg cgaccacgaa tgtcgatacc gtcggcctga cggaatatcc
   612601 gggcgcgctg atcatcaaca agcgcttctc gaacattcct ccgggcgcgc cgatcttcat
   612661 gttcaactgg gcggaagaca cgatcatccg cgaaagggtc ttcgttgccg ccgacaagca
   612721 gggcgatttt gagctctatc ccgagcagct tcccggcaag cccggcgaaa gcggcccgat
   612781 caactgaaac tgaaccgccc ctgccggctc cgtaaaagga gggggcaggg gtgcaagccc
   612841 ttcaggccgc cgcgagccgg tgcaggcatc gtctcgcggc actctaagac agaaggaaac
   612901 ggcatgttca gatttctgct cgtccgcatc gcctctgcca ttccggtgct cctcgtcttg
   612961 agcgtggtga ccttcggcat catccaggca ccgcccggag actatagcga ctacatccgc
   613021 tcgcaactca tcaatcaggg aggcgcttct ttcgaggaag ccgacgccca ggcgcaagcg
   613081 taccgcaagg agcacggtct cgataggccg ctgcctatcc agtacgtcga ctggataacg
   613141 ggcatcgtga cgcgcgggga tttcggccac agcctctatt acaacaagcc ggtcgccgac
   613201 gtcgtcggcg agcgtctgcc gcgcacgctg gcattggcgc tggtctgcca cattcttgca
   613261 tccgtgatcg gcatcgcctt cggtatcatc gcggcgacgc ggcaatattc ctggatcgac
   613321 agcctgcttt cgaccatatc gttcctcggg atgacggtgc cgcgcttcct catggcgctg
   613381 atcatcgtct atattctcgt cttccatttc aatgtgagcg agatcaacag cttccattcg
   613441 gcgcgctacg gcggggcgcc ctggtcctgg gagaaattcg tcgacctggt gaagcatgtc
   613501 tggccggtcg tcgcgatcgc caccttcggc gggctcgctt acaacatgcg ggtgatgcgt
   613561 ggcaatctcc tcgatacgct gaatgcgcag tatgtcgaga cggcgcgggc caagggactg
   613621 agcgagggcg cggtcgtcat gcgccatgcg gtgccgaatg cccttcatcc gctgatcatg
   613681 tatcagggcg tcgtgcttcc ttacatgctg accggggaga tcgagactgc catcattttc
   613741 gctttgccga ccgtcggtcc ggcgatcgtg ggctccatgt gggtaggcga cgtctatgtg
   613801 acggccacct tcatgctggt cctttccgca acgctgatcg tcggcaacat catagccgac
   613861 atgatgctcg ccgcgctcga tccgcgcgta cgcatgggtg ggggggcata cgcatgacca
   613921 tcgaagtagg aagtacgctt ccgctggccg tcgaacccga ggaaaagcac caccacgaga
   613981 gctactccgc actcgtatgg cgccgattga agcgctcctg gaccggcctg ctcggcctga
   614041 tcctcgtctg cctgctgatc ctgatggccg tctttgccga tttcctgtcg ccggtggatc
   614101 cgaaggtgac ggatgtcgcc ttcgcgcagc cccagacgat cagtttccgc gacaaggacg
   614161 gcaatttcgt ctttccgccg cggagctatc cggtgcggga gacggaggaa ctcgatccga
   614221 tcaccttcca gccgatcatc ggccccgact acgaaaatcc acaggtgctg ggcttcttcg
   614281 tcaagggcgc tccgtaccgg ctcttcgggt tgatcccggc cgagcgccat ctcttcggcg
   614341 cagtcgacgg aacgccggtg catctgctcg gcaccgacaa attcggccgg gacgtactgt
   614401 cccgcattct ctacggctcg cgcatctcgc tgatgattgc gctcaccgtt gtcttcatcg
   614461 tcacagtggt cggcacgacg gtcggcatgg tttccggcta tttcggcggt cgcttcgacg
   614521 cctgggtgca gcgcttcgtc gaactcgtgc tcgcctttcc gcaattgccg ctctatctgg
   614581 cgctcgcctc gctgattccg gttacagcgc cgaccaacgt cttcctcgcc ttcgtcatca
   614641 tcgtaatgtc ggcgctcggc tgggcgcaga tgtcgcgcga ggtgcgcggc aagaccctgg
   614701 cgcttgcccg gatcgaatat gtgcgggcgg cgatcgccat cggcgcgacg gatcggcgca
   614761 tcatcttcca gcacatcttc ccgaatgtga tgagccacgt catcgtcgcc gtgacgctcg
   614821 ccattccgca ggtggtgctg cttgaatcct tcctcggctt cctcggcttt gcggtcaagc
   614881 cgccgctgat ctcctggggg ctgatgttgc aggacacggc caattattcg gcgatcggtt
   614941 cctatccctg gatcctctcg cctgtcgcct tcgtgctcgt caccgtcttt gccttcaacg
   615001 cgttgggcga cggcttgcgc gacgcaatcg acccctattg aggagcacgc cgatggctac
   615061 gatcgaaagc attgtcccgg caccggaaga acggcgtgac cgccacacga aggaagcgag
   615121 accggtcatc gacgcccgcc gggtcgccgt gagcttcaag gtcgaaaacg gtgcggtcga
   615181 ggcggtgaag gacgtctcct tccagctcta tcgcggagag accgtggcga ttgtcggcga
   615241 atccggttcc ggcaagtcgg tgacggcgcg caccgtcatg ggactcttgt cgaaacgcgc
   615301 tacgatcgcg ccgcaagcgc ggatcgaata tgatggcaag gacgtgctga aattttcgaa
   615361 gagagaacgc cgggcgttgc gcggcgatcg catttcaatg atctttcagg agccgatgag
   615421 ctcgttgaac ccggtctata cgatcggcag tcagatcgtc gaggcgatcc gcgcccatcg
   615481 gcgcgtcggc cgccgcgctg ctgcggagcg ggcgctggag ctcttgcgcc acgtgcagat
   615541 cccggacccg gaagcgcgcc tgaaccaata cccgcatcag ctttccggcg gtcagcgcca
   615601 gcgtgtgatg attgccatgg cacttgccaa cgatccggac gtgctgatcg ccgacgagcc
   615661 gacgacggcg ctcgacgtca ccgtgcaggc gcagattctc aatctcatcc gcaagctgca
   615721 gcaggaactc ggcatggcgg tgattttgat cacccatgac ctgacggtgg ttcgccagtt
   615781 ttccgattat gtctatgtca tgcagcttgg agaggtgaag gaacacaaca cgacggaagc
   615841 gctctttgtc gatccgcagc acgcttatac gcgccggctg cttgcctcag agccgtccgg
   615901 ctccgccaat ccgctgcccg ccgacgcgcc gatcatgctc gacggcagaa acgtccgcgt
   615961 ctccttcacc ttgaagaagg gcgggttttt caggccggaa tacaaggagc tcatcgcggt
   616021 ggacggcctc agcctcaatc tgcgtcggca cgagacgctc gggctggtcg gagagtccgg
   616081 ttccggcaaa accaccttcg gtcaggcgct gatccggttg atcaacaccg atggcggcga
   616141 agtctatttc gagggcgaac cgatccacga caaaaaccgc aaggcgatgc ggccgcttcg
   616201 ctcgaagatc cagatcgtct ttcaggatcc tttttcctca ctcaaccccc gtatgtcggt
   616261 cggccagatc atcgaggaag ggctgatcgt caacggcatt ggcgaaagcc gcaaagacag
   616321 gctgaagcgc gtcgaggacg cgctcgtcag cgccggcatg cccgccaata tcctgtcgcg
   616381 cttcccgcac gagttctccg gcggccagcg ccagcgcatc gcgatcgcgc gcgccatcgc
   616441 gctcgagccg gaattcattc tgctcgacga gccgacctcg gcgctcgacc tgtcggtgca
   616501 ggcgcagatc atcgagctcc tgcgccggct gcaggacgag cggggcctga gctacctctt
   616561 catctcccat gacctgaaag ttgtgcgggc gctctgccac cgcgtggcgg tcatgcagaa
   616621 cggcaagatc gtcgaagagg ggcccgtaag cgaaattctc aacagaccca agactgccta
   616681 cacggagcgg ctggtaaagg ccgccttcga agtggctgcg tgaattcgaa cagaggctat
   616741 tcccagaggc tattccatga cgagacaacc caggatcact ttcatcggcg ccggttccac
   616801 cgtgttcatg aagaacatta tcggcgatat cttgcagcgc ccggcgcttt cggccgcgac
   616861 catcgccttg atggacgtca acccggagcg cctggcggaa agcgagatcg tcgcgggcaa
   616921 gctggcgcgc acgctgggcg ccggcgccag gatcgagacg cactccgacc agcgcaaggc
   616981 gctcacggga gcggacttcg tcgtggttgc cttccagatc ggcggctacg agccatgcac
   617041 cgtgacagat ttcgaggtgc cgaaaaaata cggactgcgc cagacgatcg ccgacacgct
   617101 cggcgtcggc ggcatcatgc gggggttgcg caccgtcccg catctctgga agatctgcga
   617161 ggacatgctc gaggtctgcc ccgaggcgat cctcctgcaa tatgtaaacc cgatggcgat
   617221 caacacctgg gcgatcgccg agaggtatcc ggccatcaag caggtgggcc tctgccactc
   617281 cgtgcagggc acggcctatg aactcgcccg cgatctcgag ataccgctcg aggagatccg
   617341 ctatcgcgcc gccggcatca accacatggc cttctatctg aaattcgagc accgtcagaa
   617401 ggacggcagc tatcgtgatc tctatccgga ccttatccgc ggctaccgcg aggggcgctt
   617461 tccgaagccg agccattgga acccgcgctg cccaaacaag gtacgttacg aaatgctgac
   617521 gcggctcggc tatttcgtca ccgaaagctc ggagcatttc gccgagtaca cgccctattt
   617581 catcaaggag gggcgtcccg atctgatcga aaaattcggg attccgctcg acgagtatcc
   617641 gaagcgttgc atcgagcaga tcgagcgctg gaagggccag gcggccgcct tcaaggaggc
   617701 ggagacgatg gaagtcgcag agagccgcga atatgcctcc tcgatcatga actcggtctg
   617761 gaccggcgag ccctcggtga tttacggcaa cctcagaaac aatggctgca tcacctcgct
   617821 gccggaaaac tgcgcggcgg agatgccgtg tctcgtcgat cagtcgggta ttcagccgac
   617881 ccatatcggc gcgctgccgc cgcaactcac ggcgttgatc cgcaccaaca tcaacgtaca
   617941 ggagttgacg gttcaggcgc tcgtcactga aaaccgggag catctctacc atgcggcaat
   618001 gatggatccg cataccgccg ccgagctcga cctcgaccag atctggtccc ttgtcgacga
   618061 tctgctcaca gcgcaccgcg actggatccc ggaatgggcc cgcgtcgcgc agaaggtagc
   618121 ggccgcctga cttcttctcc cggtcaggcg accggaacgg ccccggaacc gaacggtccc
   618181 ggggccgtca cgtttctaca gccttttcca ttaggaaagg tctaggccta ggaccaggcg
   618241 caagcctgta gtccaataga cgtggtctgg gagatgtggg acagccaaca tacggagcgc
   618301 aagcagcaga cgccagtcat gtgttgcgac agttacgcgt tttccgaaac tggtcttagc
   618361 ggcttcaagc ctgctttcgc caatgcctga ctcaaaggcg gtaaccccat aataaggaag
   618421 catttatgat ttgaccgatt ccgtaacatc ctgatccgcg cgactgtagg aggcatcgct
   618481 ctcagtgccg tcgcattgtc cggcgcgatg gccgaagagg caaaggagca ggctcaggcc
   618541 gggtttgtaa agcgtgggac gctctcgtgc gatatcgcag caggcattgg cctggtggtc
   618601 ggttcttcga aagcgttgac atgcgttttc gaggccgacg gacagaagtc gccgcataga
   618661 tatagcggca cgatcgacaa gctgggtctt gatatcggcg taacggcgga aagccgcgtc
   618721 gtgtggcagg tttatccgaa gccgaaaacc aagctcaagg gtgctcttgc cggcacctat
   618781 tccgggcttt ctgccgaatt cgcagcgggc ctgggtctgg gcgcgaaatc cctggtcggc
   618841 tcgaaaaagt aaatcgcgct gcagccggtg aagatcgacg ggcaaaccgg cctgaacgtt
   618901 gccgttggaa tcgcaagcgt gaagttgacg atggtgaagt aatcggcacg aagccactgc
   618961 cacaattagc ctccgcgttt gcgaacaccg caacaggttc gaggcagtta acgacagcgc
   619021 cgcgcgtctt atcagacgcg cggcgctgtc gtgttttgat cgtttgcgcg ttttgttctt
   619081 gaacggcctg cagttaaagg aaacatgcag ggaattggaa aagagacggt ggtggaatgc
   619141 aggggcaggg cgacaactcg gcaaaggcgg gctcaaaggc catccgggaa attctggatg
   619201 aagtgcccct ccgagccgcg agcttcatcg tcacgatcta tggggacgtg gtcgagccac
   619261 gcggcggcgc gatttggatc ggcaacctga tcgagatctg cgccggtgtc ggaatcagcg
   619321 aaacgcttgt gagaaccgcc gtatcccgcc tcgttgcagc cgggcggctt gccggagagc
   619381 gggagggacg gcgcagcttt taccgcctca ccgatgccgc gcgtacggag ttcgccggcg
   619441 ccgcgcgggt tattttcggg cctccggagg aggcgagctg gcacttcgtg cagctgatgg
   619501 gttcatcggc cgaggaccgg atgctgatgc tcgaacgatc cggttatgcg cgcctgagcc
   619561 ctcggcttgc aatcggcgtg cggcctttcc cgaccgcgat catgcccgcg ctggtcttca
   619621 gagcggagat tgccgaaggt gcggaagagt tgaaggcgtt cgcctcggcc tcgtgggatc
   619681 tcgcacccca tgcagaggcg taccggcgat ttctcggctc ctttcaatcg cttgcagcac
   619741 ctgcggatgc tgggtcgatg acacctgcgg attgtcttac cgcgcgcctc ctgctggtgc
   619801 atcagttccg ctttgtggcg ctgcgcgatc cgcgcctgcc tgccgaaacc ctcccggaag
   619861 gctggccggg tgacgaggcc cgccggctgt tcgccaggct ctacctcaat ctttctcatc
   619921 cggctgacct gcatgcggcg cagcacttcg ttgcggcttc ggggccgctg gcagcctcca
   619981 cgggagcgac cgaggaacgg tttcggatgc tgcggaggga aggtgttccc gcgagcggct
   620041 gtaaatccgt ttgacctatt gctgtggcat cccccggcat ttaatgtcac aaaaaaccgt
   620101 gattcagtcg ttgaactgtg acatgtcctg cgctagattc aagaagggtc tgtatcgggc
   620161 atgccggtca cgcgttcgaa ggagttgcat acaagcgtcg tcatcattca cgggcgcgtc
   620221 cagcggagga aggggccatg tatgctcaaa tggtgaagac ggacgccccc cgcattaaaa
   620281 gccggagcga gatggatcct cgtgagcgcg ctttccagga gcggatcgat gcgggtcaga
   620341 agatcgagcc gaaggaatgg atgcccgaag gctaccgcag gacgcttatt cgccagatca
   620401 gccagcacgc ccattccgag atcgtcggcc agcttccgga aggcaactgg atcacccggg
   620461 cgccgacgct cgagcgcaag gcgatcctgc ttgccaaggt gcaggacgaa gcgggtcacg
   620521 gtctctatct ctactgcgct gccgagacat tgggcgtgag ccgagatgcc ctttacgacc
   620581 agcttcactc cggcaaggcc aagtattcct cgatcttcaa ttatccgacg ctcacctggg
   620641 cggatatcgg cgccattggt tggctcgtcg atggtgcggc gatcatgaac caggtgccgc
   620701 tgcagcgctg ttcctacggt ccctatgcgc gggcgatggt ccgcatctgc aaggaggaaa
   620761 gcttccatca gcgccagggc tacgacatcc tgatgaagat ggtgaagggc acaactgcgc
   620821 agaaagccat ggtgcaggac gcactggacc gctggtggtg gccgtcgctg atgatgttcg
   620881 gcccgtccga cgacgcttcg gtgcattcgg cgcagtcgat ggcctggaaa atcaagcaga
   620941 attccaatga cgaactccga cagaaattcg tcgatcagac cgtgccgcag gcggagtatc
   621001 taggcctcac cgtgcctgat ccggatctga cgtggaacga ggaaaagggc ggctacgatt
   621061 tcggcgagcc ggactggaac gagtttttcg aggtgatcgc cggcaacggc ccttgcaatg
   621121 gcgagcgcct cggcgcgcgc cggcaggcct gggacgacgg cgcctggttc cgggacggcc
   621181 tgacggcaca cgccgaaaaa gccacggcac gtcgtgcgca ttcggttgga gccgagtaga
   621241 attcgggagc gaacacatgt ccagcgaatg gcccctctgg gaggtcttca tccgcggtca
   621301 gcacggcctc aatcaccgcc atgtcggcag tctgcatgca ccggacgcgg aaatggcgat
   621361 caacaatgcc cgcgacgtct atgtcaggcg gaacgagggc gtcagcatct gggtggtgcg
   621421 ttcaatcgac atagtggcaa gcgcaccctc tgagaaagga ccgctgttcg agccttcgaa
   621481 cgcaaaggtc taccgccatc cgactttctt cgacattcct gatgaggtgg ggcacatgtg
   621541 atggctcaga cgattgcgat agaggcggcc gtcgaacggt ccgcgctgtt cgagtttctt
   621601 ctcggcatgg gcgacaatac gctcgttctc ggccatcgcc tttccgaatg gtgcggccat
   621661 tccccggcac tcgaggagga catcgcgctc gccaatacgg cgctcgacct catcggccag
   621721 acgcagctct ggcttggcct cgcaggcgag gtcgagggca agggccgcaa tgcggacgat
   621781 cttgcctttc tccgggatgt gcgcgaattc cgtaaccttc tgcttgcgga gcggccgaac
   621841 ggggattacg gcaggaccct gatgcgccag ttcctgttcg acgcatggca ctatcttgcg
   621901 ctgaaaggcc ttcgcgcttc ctccgatccc cgcattgccg cgatcgccga gaaaacctcg
   621961 aaggaggtgg cctatcacct cgaacgcagc cgtgatctcg tgatccgcct tggcgacggc
   622021 acggcggaaa gccatgcccg gatgaaaaag gcgctggacg agctctggtc ctataccggt
   622081 gagatgttcg tgaacgaggc gcacgacgcg gcccttgcgg ctgccggctt ggcaccggag
   622141 ccggaaagcc tagaggccga atggaatacg ctcgtcgcag aaacactctg cgcggctacg
   622201 ctcggaaaac cgcagggcgg ctatatgcac aggggcggaa agcgcggcct ccatacggag
   622261 cacctcggct atgtgctcgc cgagatgcag ttcctgcagc gcgcctatcc gggtgccagc
   622321 tggtaggagg ctcatgtggc aacggcgcta cgcccttcga tcgaagatgt ctggaactgg
   622381 ctttcgcacg tgccggatcc cgaaattccg gtcatctcgg tgacggatct cggcatcatc
   622441 cgcgacgtcg cctgggatcg cgaggcgctg gtggtgacgg tgacgcccac ctattctggc
   622501 tgtcccgcaa ctgcggtcat caatcaagac atcgagcggg cgttgaagga gaaaggcatc
   622561 gagaatgtca ggctcgagcg ccggctctca cccgcctgga ctaccgactg gatcagtgcc
   622621 gagggccgcg agaagcttgg aaactacggc atcgcggccc ctatagacgg caccaccgcc
   622681 gaaggcaggc tcatggaaag gatcgcaggc ctcgccggtg gcgcgcccct gacggtccaa
   622741 tgtccgcgct gcaattccgg gcggaccgag aagatcagcc agttcggctc gacgccttgc
   622801 aaggcgagct atcgctgtcg cgactgtttg gaacctttcg actatttcaa gtgcatctga
   622861 agggtgccgg gagaccgttt gaatggcacg ttttcacccc ctacaagtca ccgaagtccg
   622921 gcgcgagacg cgcgatgcgg tcgtcgtcac gctcgagccg cgcgatgagg accgcgccgc
   622981 tttcgatttc acgcaggggc aatacctgac cttccgccgc atattcgacg gcgaggaact
   623041 gcgccgttcc tattcgatct gctccggcct cggcgagggc gccttgaggg taggcatcaa
   623101 acgcgtcgac ggaggttgct tttccaactg ggcgaatgag gtgctcaagc ccggcgacac
   623161 gcttgaagcg atgccgccga tggggacttt cttcgtgcct gtcgaaccgg aggtgtccag
   623221 acactatctc ggtttcgccg gcggcagcgg catcacgccg gtgctttcgc tcgtcaaaac
   623281 ggtgctcgcg cgcgaaccgc ggtccgcatt cacgctggtc tatgccaatc gccacttcag
   623341 ctcgatcatg tttcgcgagg aactggacga cctcaagaac ctctatctcg gccgcctctc
   623401 ggtgctgcat attctcgaga gcgaagccca ggacatcgat cttttcagcg ggcggctcga
   623461 tttggaaaaa tgcactgccc tgttccggca ctggatcgac gtgaagtcag ccgatatcgc
   623521 cttcatctgc ggccccgaac cgatgatgca ggcggtcgcc gcaacccttc gcgcgcacgg
   623581 tgtgagcgac agccggatca ggttcgaact gttcggttcg tcccagcctg gccgcgcccg
   623641 ccgaaggacg gcaagccccg ccggcaccga tggagggtcg cgctgcgaag cgaccgtgac
   623701 tctcgacgga gccacgcgca gcttcaccct tccgaaacgg gggcagagcc tcctcgaagc
   623761 ggcgctcgaa aacaggatgg atgcacctta tgcctgcaag gctggggtct gctcgtcatg
   623821 ccgcgcaaag gtgctcgaag gcgaggtgga aatggagagc aacaacgcgc tcgaggatta
   623881 cgaggtagag cagggctatg tgctgatgtg ccagtcctat ccgctgagcg atcgcgtcgt
   623941 cgtcagctac gacgagtgaa cgaaaccggg gagagccggg gaggagcatc cgatgggtat
   624001 ggtgacagac cggccacgca ggcttgagag ctatgtcgcc ggcgtttggg tgcgtggcga
   624061 caaggacggc gtgacgctct gcgatgcggc gaccggcgcg ccggtggcgc tcgtggattc
   624121 caccggtatc gatttcgccg ccgcgctcgc ctatggccgc gagaagggcg gaccggcgct
   624181 tcgccgcatg tcgctccacg agcgggcgat gatgctgaag atgctcgccc aggccctgat
   624241 ggagcgcaag gaggaattct atgcgctctc caccgctacg ggcgccacgc gtccggacag
   624301 ctggatcgac atcgaaggcg gcatcggcac gcttttttcc tacgcctcga aggcacggcg
   624361 ggagctgccg aacagccgcg tgcttctgga cggagacgtc gagcctctct cgcgcgacgg
   624421 aacgttctcc gcacagcaca tgttgacgcc gcttcagggc atcgcggtgc acatcaatgc
   624481 tttcaatttt ccctgttggg gcatgctcga gaaattggcg ccgaccttga tcgcaggcat
   624541 gcctgcaatc ataaagcctg cgagccagac cgcctacctt gccgagttgc tggtgcgccg
   624601 gatcatcgag accggactgc ttccgcaagg cgcgctccag ctcgtctgcg gctcggccgg
   624661 cgatctcctc gatcatgccg gcgatcagga cgtggtgacc tttaccggct cgtctgcgac
   624721 cgggcgcatg cttaaggccc atcctgccat tctgaagaat tcggtgcggt tcaccatgga
   624781 ggccgatagt ctcaacgccg ctgttctcgg cctcgatgcg gctcccggaa cggaggagtt
   624841 cgatctcttc gcccgcgagg tcttccgcga gatgacgtcg aaggcaggac agaaatgcac
   624901 ggcgatccgc cgggtgatcg tgccacgcgc ccattgcgat gctctagtgg ctgctctcgg
   624961 cgagcggttt gccaggcttc cgctcggcgc tccggctgac gaaaacgtcc gaatgggccc
   625021 gctcgcaagc ctcggccaac gcgaagaggt gagggcgcgc atccgcgatc ttgccgcgga
   625081 ggcggaaatc gttgccggcg atccgacaag gccgcagctc gtttccggcg atgcggaggc
   625141 gggcgccttc ctcagtccgg tgcttctcta ttgcgacagg ccgagcgcgg cccgagcggt
   625201 ccacgatatc gaggccttcg gccccgtcag caccgtcatg ccttatgaaa cgaccgatga
   625261 cgcaatcgaa ctcgtcaggc gcggaaaggg gagtctcgtc acctccgtct tcaccaacga
   625321 tcccgataca gcgcaggaac tggtgatcgg catggcgccc ttccatggcc gtgtgctgat
   625381 cggcaaccga ttgagcgcga agtcctccac cggacacggc tcgcccttgc cgggtctcgt
   625441 ccatggcggt cccggccggg ccggcggcgg agaggaactg gggggtatgc ggggcgtcaa
   625501 acactacatg cagcgcacgg ctgttcaggg tccgccgggc ctcatatcag ccgtcatggg
   625561 ccgctggata aaaggtgcgc cggggcggca cgagagcgag caccccttcc gcaagtcgct
   625621 cgccgaattg cggaccggtg atcagctcgt caccgggacc cgcgtggtga cgctcgaaga
   625681 tatcgagcat ttcgccgatt tcaccggcga taccttctac gcgcatatgg acgaggaagc
   625741 cgcgcgcgcc aatccgttct tcgacgggcg ggtcgcccat ggctatctcg tcgtttccct
   625801 cgccgccggt ctcttcgtcg atcccgcccc ggggccggtg ctcgcaaact acggtgtcga
   625861 cgggctgcgc tttcttgcgc ccgtctatcc gggcgatgcg ctgcaggtcc ggctcacctg
   625921 caaggagatc agtccgcgga tgaacaccga atatggcgag gtgcgctggg actgttgcgt
   625981 caccaaccag actggcgcga ccgtcgcgca atatgatgta ttgacgatgg tagcaaaagc
   626041 gcgcggtgag gaaaaatgat gacggatcag gagacgcgac atctggtgat gaccgttctg
   626101 atgacgccgg acatggcgaa tttcagcggc aaggtgcatg gcggtgcgct tttgaatctg
   626161 cttgaccgtg tggccttctc ctgcgcgtca cgcttttcca agcaatatgc ggtcaccctc
   626221 tccgtcgacc aggtgatctt caaggagccg atccttgtcg gcgaactcgt cactttccgc
   626281 gcggcggtca attttgccgg gcggacgtct atggaggtcg gcataagggt cgaggcggaa
   626341 aacatccgtg ccggcacccg acggcacacc aattcctgct atttcaccat ggtcgccgtc
   626401 gatgaagcgg gccgcccggt ggcggtgccg gagtaccgtc cggagacggc aaccgagaaa
   626461 cgccgccacc aagcggccga actgcggcgc acgctgcgcc gcgaatttgc tcatcggctg
   626521 aagaccgtcg cggaaaccgg ccgtgatgtg gtggattaga ccagacggac gagcgccctt
   626581 cgatgtaggc gtatgcgcat gtggcccgcc gcgcccgtca ccggcccttg aactccggtt
   626641 tgcgcttgtc gaggaatgcc gtcacgcctt cggcataatc ggcgctgcgg ccagcttcgc
   626701 gctgcaggtc gcgttcaagg tcgagctgtt cgtcaaagga atgggtggcg gccgcctgga
   626761 tggcgcgctt ggtcaagccg aaacccctgg tcggtccggc tgcgagcctg gcggcgagcg
   626821 cgaaagcctc gtccatcagc gccgcgtcat cgacggcgcg ccagatcagc ccccagctcg
   626881 ccgccgtctc tgcatcaagc ggttcggccg tcagcgtcaa cgccttggcg cgcgcctcgc
   626941 cgacgagccg tggcaggttc caggttccgc cggaatcagg tatcagcccg attttcgcga
   627001 aagcctgaat gaagcgtgcg gagcgggcgg caagcgtgat gtcgcaggcg aaggcgatat
   627061 tggcgccggc gcccgccgca actccgttga cggcgcagac gaccggtttc tccagcccgc
   627121 ggatcagtct caggagcgga ttgtagaagg tctcgatcgt atggccgaga ttcggcgtac
   627181 cgccgccgtg cggatcgcga tcgccaagat cctggccagc ggaaaaaccg cgcccggccc
   627241 cggtcaggag cacggcccgc acgtcatcgt ccgaatgggc gcgctcgaag ccggcacgca
   627301 gcgcaaggtg catctcctcg ttgaaggcat tgagcttgtc cggacggttg agcgtcaggc
   627361 gcagaacgcc ggtctcaaac gccgacagaa cggtgtcgga agcggacatg tttcctccct
   627421 gcaccagctg gttcccgccc ttgaaagcct tacatggacc ggccggccgg tcaatcatgg
   627481 cgccacggag gataagcatc atggccctga acatcgtgca tagaggcggg gtcgcgcttg
   627541 ccaccaccgg caatcctctt cgccacgttt tccgcgccga acgggtggcc agacacgcgc
   627601 cggagcttgc cggcgtagag ccgcgaccga tccgctcggc ggcggtgatc ggcggcggca
   627661 ccatgggcac cggcatagcc gcggcgcttt gtaacgccgg ccttcctctc gttatcgtcg
   627721 agcgcgacga ggcggcgagg gaaggcgcgg tggcgaggct ccgcgcaatt ttcgacggcg
   627781 cggtaaaacg ccgccgcatc tccgccgggc ttgcggcgga gcgcttggcc cgcgtcacag
   627841 gcgcgaccga ttacgcagtg ctcgccgagg cggatcttat catcgaggcc gtcttcgagg
   627901 acctggatgt gaagcgcgat gtctttcgaa aggtggcggc cgcctgccgg cacgacgccg
   627961 ttctcgcgac gaacacgtct tatctcaatc ccgagcgcat cgccgatggc attgccagcc
   628021 cggagcgctt cctcggactg catttcttca gtccggcgca ggtgatgaag cttctcgaaa
   628081 tcgtccccac gggggcgacg gcacccgagg cgctggcgac cggtttcgcg ctggcacgga
   628141 tgctgaacaa aattcccgtg cgcgccggca tttcggacgg gttcataggc aatcgaatcc
   628201 tgaaggtaat gcggggccag gccgaacggc ttctcgtcac cggcgccagt ccctccgccg
   628261 tcgatgccgc catgcgcgct ttcggtctgc cgatggggcc tttcgaagca caggatctcg
   628321 gcggcctcga tatcgccgcc ttccagcggc gcgccgcccg ggcgcgcggg ctgccggttt
   628381 tcgcgccggt ttccgatcgc ctctgcgcaa tcgcccgctt cggccagaag agtggcggcg
   628441 gctggtacga ctacgtgccc ggccaccgca caccgctgcc ttccgaggca gttgcacgcc
   628501 tcgtcgagga ggaggcacag ggttggccgc gccttgattg ggacgaggcg tccatcatcg
   628561 actgcattct ctggccgatg gtcaacgagg cggcgcggat cgtcgaggat ggaacggctc
   628621 tcaggccatc cgatatcgac ctcgtcgaga ttcatggcta tggctttccg cgctggcggg
   628681 gcggtctgat gcatcatgcg caggcccagg gtctcgaccg gatcgtcgca gcgctcggcg
   628741 cctttgccga gaagggtctc gccgatcccc ctagcactct gctcgtccgg gctgccgccc
   628801 aaggccgttt ctcggaggca ttgaggtagc gcgcatggga acgcgtttcc ggtcaggcgt
   628861 ttgactcgat tgcgggtcgg gcattttgtc ccgggtaggc cgcgccgggt tgcagaagcg
   628921 cccccatttt cctaggagga cccctttcgg attcagaaca gacaggtcct gccttgatcg
   628981 agacgcccta ttatctcatc gacaagtcca agcttatccg caacatggag aagatcgccc
   629041 atgtgcgcga gaagtccggc gccaaggctt tgctggctct caagtgtttt gccacctggt
   629101 cggttttcga cctcatgcgt gactatatgg acggcaccac gtcttcctcg ctcttcgaag
   629161 tgaggctcgg ccgcgagaag ttcggcaagg aaacccatgc ctacagcgtc gcttatggcg
   629221 acaacgagat tgacgaagtc gttttgcatg ccgacaagat catcttcaac tcgatctcgc
   629281 agctcgaacg ctatgcggaa agagccgcgg ggatcgcgcg cggattgcgc ctcaatccgc
   629341 aggtgagctc gtcgagcttc gaccttgcgg atccggcgcg tcccttcagc cggcttggcg
   629401 aatgggacgt ggcaaaggtc gagcgtgtca tggatcggat caacgggttc atgattcata
   629461 acaactgcga aaacaagaac ttcgacctgt tcgattgctt gcttgcgcaa atcgaggaac
   629521 ggtttggttc gctgctcgaa cgcgccgatt gggtgagcct cggtggcggc attcacttca
   629581 ccggggatga ttatccggtc gacaccttct cggcgcggct cagagcgttt tcggaccgct
   629641 acgacgttca ggtttatctc gaaccgggcg aggcctcgat cacaaagagc acgacgctcg
   629701 aagtgacagt gctggacacg ctctataacg gtaaaaatct cgctatcgtc gacagttcga
   629761 tcgaagcgca catgctggac ctgttgattt atcgcgaaac cgccaaggtt tcgccgaacg
   629821 aggggccgca tagctacatg atctgtggca agtcctgtct cgcgggcgat gtctttggcg
   629881 agttccgctt tgccgacgcg ttgaaggtcg gcgaccgcat ctcgtttcag gatgccgccg
   629941 gttacacgat ggtcaagaag aactggttca acggcgtgaa gatgccggcg atcgccatca
   630001 aggaacttga cggaagcgtc aggaccgtcc gcgaattcac ctacgcggat ttcgagaaga
   630061 gcctctcctg aggcttcagg taaagacggg tagaaggaga tatcccccga aatgaagaaa
   630121 aacgttctca tcatcggcgc cggtggcgtg gcacaggtcg tggcgcacaa atgcgcccag
   630181 aacagcgatg tattgggaga tattcatatc gcgtcgcgca cggtcgagaa gtgccgcgca
   630241 atcgtcgagt ccgtgcggga aaagaaaagc ctgaagacgg aggtgaggct cgaggcacat
   630301 gcgctcgacg ccctcgacgt cgaggcgacg aaagcgctca tcgcgagcac cggctcaaag
   630361 atcgtgatca atgtcggttc ggctttcgtc aacatgtcag tgcttcgcgc ctgcatggac
   630421 accggtgtgg catatatgga cacggcgatc cacgaggagc cgaacaaaat ctgcgaaacg
   630481 ccgccgtggt acggtaatta cgagtggaag cgcgcagcgg agtgcaagga gaagggcatt
   630541 accgccattc tcggcgtcgg cttcgacccg ggcgtcgtca acgcctatgc gcgccttgcc
   630601 aaggacgatt atttcgacaa ggtcaccgcc atcgatatcg tcgacatcaa cgccggcaat
   630661 catggcaaat atttcgccac caatttcgat ccggagatca atttccgtga atttaccggc
   630721 gtcgtctatt cctggcagaa gggcgcctgg cagacgaacc gcatgttcga aatcggcaag
   630781 gagttcgacc tgcccgtcgt cggcaagcgc aaggcctata tgaccggcca tgacgagatc
   630841 cactcgctgt cgaagaacat ggacggcgcc gatgtgcgct tctggatggg gttcggcgac
   630901 cactacatca acgtcttcac ggtcctgaaa aatcttggac ttctttccga gcagccggtg
   630961 aaaacggctg aagggctcga ggtcgtcccg ctcaaggtcg tcaaggccgt gctgcccgat
   631021 ccggcgtcgc ttgcccctgg ctacgaaggc aagacctgca tcggcgactt cgtcaagggc
   631081 ttcaaggacg gaaaagagcg cgaagtgttc atctacaacg tcgccgatca caagcaggcc
   631141 ttcgaagaag tgggttcgca gggcatctcc tacaccgccg gcgtcccgcc ggttgcggcc
   631201 gcaatgctga tcgccagcgg cgaatgggat gtaaagcaga tggcgaacgt cgaagaactg
   631261 ccgccgcggc ccttcctcga cctcttgagc cgcattggtc tgcccacacg catcaaggat
   631321 gccgagggtg accggccgct cagcttttcg taatcatgtg gcggccgtac aatcggcctg
   631381 cattctccgc cggaagcgga gaaaaacacc cacttcgaat tgtggcgggt cccctgcggg
   631441 gcccgtcact gccgaggggc ggattcgcaa agatctgctt tcgccgaata atcataggtc
   631501 tcttagggaa aaccttttcc catattgact ttgagagtga gaaaaggttt tctcatccct
   631561 ggttctctcg ggaggaggcg aaactgagct ctcagcgcgg caaggggcat cgcgtcacca
   631621 ttcacgatct ggcgagggtc gccggcgtga gtgtttcgac cgtgtcgaag gcactcaacg
   631681 acaatggccg catggccgcc gacacgcgcg agcggatcaa gactcttgcc gcggagatcg
   631741 gctttcgtcc gaatgcgctg gcgaaagggt tgctcagcaa ccggagcttc accgtcggtc
   631801 ttctgacgaa cgatacctat gggcgcttca cgcttccggt catggccgga atatccgagg
   631861 cgcttgtgga tcatggcgtg tcggtctttc tttgcgccat cgaggatgac ccggccctgg
   631921 gaaaaatcca tgtcgacgcc atgctggaca agcaggtgga cggcatcatc gcgacgggca
   631981 agcgggtcga caggtctctc ccggtcgacc tcgctggcct gccggtgccg gtcgtctacg
   632041 ccttcaccaa gggcgagccg ggcagcgtga cgctgacgtc ggatgaccgg cacggagcga
   632101 ggcttgccac cgagtggctg aaggagcttg gccgccagcg gcttgtccat atcaccggcc
   632161 cgcgggaatt cgtatccgct gtggagcgcg ctgaggcgtt ccgtaccgtg gctggcaacg
   632221 gcgcgccggt gctgcacggc gtctggtcgg aggcctgggg ccacgaagcg atcgacagga
   632281 tctggaaaga gggcggcgaa aggcccgacg gcatcttttg cggcaacgac cagatcgccc
   632341 gcggcgtggt cgatgcgctt cgcgagcgcg gcgcccgggt gccgggggat gtctcggtca
   632401 taggtttcga caattgggag atcatggcgg cacagacacg gccgccgctg acgaccatcg
   632461 acacgaacct gaaggaactt gggcgcgaag cgggcctgat ggtgcttgcg cttgcggagg
   632521 ggcgggcgat cgaacccggt ctgcgcaggt tgccctgcaa actggtcata agggactcct
   632581 gcggaggcgg gcgccggcag aactgattga ggagatgggg ctcactccaa tgtggccccg
   632641 catttgggag gaatgcaaaa tgttcacgaa acttatggcg gcaacggccc tcatatcggc
   632701 cagcatgatc tcggtcgcct cggccgagac gatcagcatg tgggtgcgct cgggtatagg
   632761 cgactcgttc aaggaagtcg tgaaggccta caacacagcg cacgagaaca aggtggaact
   632821 caccgaggtg ccctttgccg agctcgtgca gaaatatgcg acggcgatcg ccggcgggca
   632881 ggcacccgac gcgctgtccc tcgacctgat ctacacgccg gcctttgcag ctgccggcca
   632941 gctggaagac ctcaccgact gggcgaaggc gctaccctat ttcaactcgc tgtcgccgtc
   633001 gcacgtcaag ctcggcacct atgaggacaa gatctacggc ctgccgctga cggtcgagac
   633061 ctcaattttc gcctggaaca aggacctcta caagaaggcc ggcctcgatc ccgaaaaagc
   633121 gccggccacc tgggaggaga tcactgccaa cgccgagaaa atccgtgggc tcggcggcga
   633181 tacatacggc ttctatttct ccggcggcgg ctgcggcggc tgcatgatat tcaccttcac
   633241 gcccctgacc tggggtgcgg gtgcggatat cctttcggcc gacggcaaga cggcgacgct
   633301 cgacacgccc ccgatgcgca aggccgtcga catctaccgc aacatgatcg cgaaggatct
   633361 ggtgccggcg ggtgctgcaa gcgacaacgg ggtgaatttc ctgagcttca ccaatggcaa
   633421 gatcggccag caaagcctcg gcgccttcgc gatcggcaca ctggtgacgc agcatccgga
   633481 gattgatttc ggcgtgacgc tgatcccggg cgtcgacggc aagccgtcct cctttgccgg
   633541 cggggacaat ttcgtcgtca ccaagggcac gcctaagctc gcggacgtca aggaattcct
   633601 tgaatacacc tattcgcccg aaggccagaa gatcatggcg aagtatggca gcctgccgac
   633661 ccgcggcgac atcgccaatg aggtgctcga gggccttgac ccgcgcctga aggtcggtct
   633721 cgacgcgatc gccgtcgcca agacgcccta cacgctgcag ttcaacgatc tgatcaacag
   633781 cgcaaacggc ccatgggcga ccttcaccaa tgccgcgatc tacggcgacg acgtcgacgg
   633841 tgccttcgcg gatgcgcaag cagagatgca gtcgatcatc gacgcggggc agtaagacct
   633901 ggcggacatg gggcggcgtg gcaaacccac gatgctgctc tgcagttccg ctcccgctca
   633961 agcttccgga agggcagacg cccttccgac accgtccaga attcctagaa aagcgcatcc
   634021 atgacgacgt caagtctcac atcaaccacg cgccggagcc gcctgaagcg gaaatccggg
   634081 tggcgcgggc tcgtctatat cgcgccggcc atggcgctgg tcacgatctt cttcgtgttg
   634141 ccagtgctct tcacgctgtg gatgagcctt cacaaatggc cgctgctcgg tgagccggcc
   634201 tggatcggtc tgcgcaacta cacgcggatg ttcaccgatg cgcgtttctt caatgcactc
   634261 ggtttcactg cccactacac cctaatcgtc accatagcga ttttcgcggt cgcctttccg
   634321 ctggcgcttt tcgtggagaa acagagacca ctggtctcgc tctaccgcac catagtcttt
   634381 ctgcctgtcg tggtggggtt ggcttccgcc tcgctgctct gggtctggct tgccaatgtc
   634441 gacagcgggc tcttcgcgcc tctcttcgcc gtgcttggtc tgaccgccga tcgcatcaac
   634501 ctgctcgcca agttcgacac cgccttcatg acgattatcg tgatggtggt ctggaaaatc
   634561 gccggcttca ccatgatcat cctgctgacc ggactgcagg cgatcccgag ggagctgaca
   634621 gaggccgccc gtatcgatgg cgccggcggc tggcagcgct tccgccatct gacgctgccc
   634681 ctgatgcgcc ggaccatggc gctggcgctc atcctttcgg tgaccggctc gatcctcgct
   634741 ttcgatcagt tctacatcat gacgagcggc ggtccgcaga acaaaatgat ttccgtcgtc
   634801 tactacatct tcaaccagtc cttcgtgtcc ttcaatctcg gctacggtgc ggcgctttcg
   634861 atcgcgctcc tcctgatcct ggtgacgctc agcgtggtcc agctctggct gctaaaggtg
   634921 ggggacgaac gcccatgagg acgcgccgtg aaatccgcgc tcgaaaggcg ctccgggaca
   634981 ggatcgccta tcacggtatc ggcataggcg cggcgttctt cttcctggcg ccctttgccg
   635041 tttcttttct cgcttccttc cggccgaaca gcgagtccgg aaggccgccg ctgccaccat
   635101 ggccgctctc cggactgagc ttcgatgcct atcgcgcact cgacagcttc ggtagcggaa
   635161 tctggcagca catgttcaac tcgctcgtcg tgtcgatcgg gaccgtcgtc ctgaccgtag
   635221 cggtcagcgt gctcgccgga tacggattct cccgctaccg ttttcccttc aaaaatgcgc
   635281 tgttcgtgct gatcatcgca acgctgatga tcccgttcca gtcgatcctg acgccgctct
   635341 tcattatcct ggcgcggctg ggactaaaca attcgctcct tggcctgatg ctcgtctatg
   635401 tgacgctgca gcttcccttc tccgtcttca tgatgcgcaa cgccttcgat gccgtgccca
   635461 aggaaatcga ggaggcggcg cgcatcgacg gcgcgcgcga cctgagactg ctcgtcaggg
   635521 tgctgctgcc gctcgtgatg ccggggattg cgaccgtgtc gatcttcgcc ttcctcaatg
   635581 cctggaacga gttcttcgcg gcgctggtgc ttctttcgag caacgacaat tacacgctgc
   635641 cggtgttgat gaccgcggtg cgcgccggcc gcctcggcgc gatcaattgg ggcgcggtgc
   635701 aggccggcgt cgcggtgatg gtcgtgccct gccttttcgt cttccttctt ctgcaacgct
   635761 attacatgcg cgggcttatg gccggcgcgg tgaaatgatc cgagagaaag cgaaccatga
   635821 caaagaccgt gaaagaccgc caattccgac cagtttccgt tcccgatgtc gagctcggcg
   635881 gattttgggg gaaatggcag gatgccgtct gccaatccac cgccgaaacc ctgctcgacc
   635941 ggtgcgtcga ggcaggcatg ctgaaggcga tcgacgtcag tcagccgagc cccggaatcg
   636001 tcattccgat ccagccatgg ggaggcacca cgcagatgtt ctgggattcc gacctcggca
   636061 agtcgatcga gacgatcgcc tattcgctct accggcgccc caacccggaa ctcgaggccc
   636121 gcgccgaccg gatcatcgac atgtacgaga agctgcagga cgaggacggt tatctgaatg
   636181 cctggttcca gcgcgtccag ccccaccgcc gctggacgaa cctgcgcgat caccacgaac
   636241 tctactgcgc cggccatctc atcgaagcgg ccgtcgctta ctatcaggcg accggcaagc
   636301 gcaagctact caatatcatg tgccgctttg ccgactacat gattacggtt ttcgggcgca
   636361 aagaaggcca gatccccggc tattgcggcc atgaggagat tgagttggcg ctcgtcaggc
   636421 ttgcccgcgt cacgggggag aagaaatatc tcgatctttc gaaattcttt atcgacgagc
   636481 gaggcaccga gccgcatttc tttaccgaag aagcgaaacg cgacggccgc gatccggaga
   636541 gtttcatcca gaaaacctat gaatacggtc aggcgcacca accggtgcgc gaccagaaga
   636601 aggtcgtcgg ccacgcggta cgcgcgatgt atctctattc cggcatggcc gacattgcga
   636661 cggagtacaa ggatgacagt ctgacggcgg cgctggaaac gctgtgggac gacctcgtta
   636721 cgaagcagat gtacgtcacg ggcggcatcg gtcccgccgc ctcgaacgag ggcttcacgg
   636781 actattacga tctgcccaac gacaccgcct atgccgagac ctgcgcctcc gtcggcctcg
   636841 ttttctgggc gagccgcatg ctcggccgcg gaccggaccg gcgctatgcc gacatcatgg
   636901 agcaggcgct ctataacggt gcgctgcccg gtctttcgat cgacggcaag accttcttct
   636961 atgacaaccc gctcgaaagc accggtcggc accatcgctg gaagtggcat cattgcccct
   637021 gctgcccgcc gaacatcgcg cggctcgtga cctccatcgg ttcctacatg tatgcggtcg
   637081 cagaagatga gatcgccgtt catctctatg gtgaaagcgc tgcgcggctg aaactcgcga
   637141 acggcgccga ggtcgagctc aggcaagcga ccaattatcc ctgggacggc gcgatcgcct
   637201 tcacggcaag actcgaccgt ccggcccggt tcgcgctgtc cctgcgcatc ccggaatggg
   637261 cggcaggagc gacgctcagc gtcaacggtt cgatgctcga tctgtcggcc catctcgccg
   637321 acggttatgc gcgcatcgaa cgcgaatggt cggacggtga ccgcgtggcg ctctatctgc
   637381 cgctcacgct tcgcccgcaa tatgccaatc cgaaggtccg gcaggacgtc ggtcgcgtgg
   637441 ctttgatgcg cggccccctc gtttattgtg ccgaggcggc ggacaatggc ggggatctga
   637501 acgcgatcgt gctcccccgc gaacttccgt ctgccgagac ggtggtcatg gaggaactga
   637561 acggcgccgt cgccgtcgac ctggcggtcg agcgtgaaga gaccgagaat tggggcaagg
   637621 cgctttaccg cgaggaaccg gctgcgcgtg tgcctcacaa ggcgcgcttc gtgccctatc
   637681 atctctggga caacagggcg ccgggcgaga tgctcgtctg ggtgcagtcc ggcagatagg
   637741 cgatagcgag gatggcgaac ggcaccggca ataagagcgt cgtgctcagc gatatacgca
   637801 agagctacgg caacctggag gtcatccatg ggatcgacct gacgatcgag gaaggcgatt
   637861 tcgtcgtctt tgtcggcccg tccggctgcg ggaaatcgac cctgctgcgg atgatcgcag
   637921 ggctcgagga ggtgacggag ggagagatcg caatcaaggg cagggacgtg acagatctcg
   637981 acccttccga gcgcggcata gctatggtct tccagtccta cgcgctctac ccgcatatga
   638041 gcgttggcga aaatctcggc ttcggactca agatggctcg gacggatccg gccgatatcg
   638101 agcgccgcgt cgcgcaggtc tcggcgatcc taaaaatcga tcccctgctt gaccgaaggc
   638161 cgggccaact ttcgggcggg cagcgccagc gcgtggcgat cggccgggcg atcgtgcgca
   638221 agccggacgt atttctgttc gacgagccgc tttccaacct cgatgccgag ctgcgcgttt
   638281 cgatgcgcat cgagatcgca cggctccacc gcgaactcgg caataccatg atttacgtca
   638341 cccacgatca gacggaggcg atgacgctcg ccgaccagat cgtcgttctg cgtgacggcc
   638401 ggatcgagca gaccggcagc ccccgcgagg tttacgagga tcccgccaac atgttcgttg
   638461 cgggtttcat cggttcgccg cgcatgaatt tccttgaggc cgaatggcag ggagacggaa
   638521 ccgtccacat cggcagcgca gcgctttggg ctccgatcga tggcagcagt ctggctccgg
   638581 gggatcgcct gaggctcggg atgaggccgg agcacctcac ggtctgcgaa cccggcgcgg
   638641 agcggatcgc cgcccaggtc gaattctcgg aatatctcgg cggcacgcgc tatctctatt
   638701 gccaacttga ggacggtcaa agccttgtcg tcgaacaacg cgaagggccg gactggcagg
   638761 tgggggagag gctatcgttt tccgtgccag aggacagaag acggttcttt gccggggacg
   638821 gccgacgttt gcgttagagc agcggaggag ggaggccggc agccggatga tggggcttga
   638881 gtgatgcggc ggcttcgtcg aatttgcggc tggcacctca ccctaaccct ctccccgcaa
   638941 gcgggagagg ggacttcggc ggcgcggcat atcccttctc cccgcttgcg gggagaaggt
   639001 tccggcagcg gatgaggggc agttgtcgcg gcgtgaccgg caatctccga atggttgccc
   639061 ggagcgcgga cacctctcac cccaacaagt gatgcctggc cgcggtcgtg acctcgcgag
   639121 tcagctccgc caggcggtcg gcggcaagtc ggttcagctg ccaatagagc ggaacgtcca
   639181 aaggcgtttc cgggatcagt tccaccagcc gcccggagct gaggtgctcg cgcacgagtg
   639241 gtgccggatt catgccccat cccatgccgg aaaggctggc ctcgatgaaa cccggggtcg
   639301 agggcagcca atgcgtcgca ggattggcgt cttcctcgaa cacctgacgg atccaccggc
   639361 actggagcct gtccttctga ttgaaggtca aggccggcgc tctgccgatg gaatttgccg
   639421 tgacaccctg cggaaaatgg cgggcgacga aatcggggct cgcagtggcg tgatagcgca
   639481 gcgcgccgag gaaaagccgg cggcagccct gaaccggctt ttccaggctg gtgaccgcgg
   639541 cgaccacacg cccgcgccgg agccattcgg cggtatggtc ctcgtcgtcg atcgcaatgt
   639601 tgagcagata gggagagtgc ctggcgaagc tcgacattgc cgtcaggaac catgttccga
   639661 gactgtcggc attcgtcgcg atgtgcagag ttactcttgg ttcgggatcc gtcggatcga
   639721 ggagatcggg cagatgctgg aacagctcgg cttcaagcat gccgacattc tccatgtgcc
   639781 ggcagagcca ctctcctttc tcggtcgcgg tgcagggatt gcctctcgca atcagcacca
   639841 cgccgagacg ttcctcaaac tgcttcaccc gctgcgatac ggccgaaggc gtcacgttga
   639901 gaaggccggc agccttttcg aagctgccgg tctgaacgac cgccgagacg gcgcggagag
   639961 cggagtagtc gagcatggat tagctgtgct taatcgtgat tagcaacatt aactagcctg
   640021 aattcaccag acgcggtagc ggaaaggctc ggcgttggga gcgatatgac atgaatattc
   640081 cggttttcgg cacagggctc gtgacgggtc tcagcctgat cgttgcgatc ggcgcgcaga
   640141 atgcgtttgt gctgcgccag ggcctgcgca acgaacatgt attcgccgtc tgcctgattt
   640201 gtggattgtc ggatgccttg ctgatcacgc tgggtgtgac aagttttcgc cagatcgcag
   640261 cattgctgcc ctggctcgat ccgatcatgc gctacggagg cgcggcgttc ctgatctggt
   640321 atggtgcgaa aagcctctat tccgcgctcc gctcatcgga agcacttgcg gtacaggagg
   640381 gggcgggttc tgcgagcgtc aggacggtcc ttttgacctg ccttgccttg acctggctca
   640441 acccgcatgt ctacctcgac acggtcgtgc tgcttggtac catctcgacc cggtttccgg
   640501 gatacgaggc gtcgtttgcg gcgggcgccg tgaccggctc gctcctgttc ttcttttctc
   640561 tcggctacgg cgcgacctgg ctgcggccga tcttctcgaa gccggcgtcc tggcgaattc
   640621 tggaaacctt catcacgctg accatgtggt tgatcgcttt taatctgctg agagatctgt
   640681 aggattcgac cgcggtcgcc ttgcgcgcta cgctccaagc gagctttctt gacaacagac
   640741 gacatgaacg ggtcctcaga gtgtccgcac aatttcacca tctcctgatc gtctatgcag
   640801 cctatgtgat cgcagccgga agtcccggtc ccagcaacat gcaaatcatg gccgtggcga
   640861 tgcatagcgg acgacgcgcg gccctgatac tcgctgccgg cgtcgtcagc ggttcgttct
   640921 tctggggcgc gatggctgcg accggcgtct cggcagtcct gacccgctat gcggaagcgc
   640981 tgatcgttct gaaaatcttc ggcggcctat atctcctcta tctcgccttc aaggccggaa
   641041 aatctgcgct tgcttccgac ccgcaaactg cttcgaatag cagccgcaat ggcgccgtcc
   641101 cgactgccgc ggagctctat cggcgcggac tgctcatgca tctcagcaac ccgaaatcaa
   641161 tccttgcctg gatcgccctg gtgacgctcg gacttggccc gggctcgtcg tggcacacgc
   641221 ttggcgcgat cctcggcggt tgcgcggtct tgagcgtcac gatcttctgc ggttatgcga
   641281 ttgtcttttc gacggcgccc atggtgcggc tctatcgtcg cgcaaggcgc tggatcgagg
   641341 gcgtattggc gctgtttttc ggctttgccg gtctccggct gctgctgtcg cgcatataga
   641401 ggtgataagg gaagctgtgg actgaaacgc tctgatagtg ggatgctatg accttgtttg
   641461 ccggccttgc ggccttttcc ataacgccag cggatgcctc ggggcatgtc gacacggccg
   641521 cgctcgcacg acttctcgaa cgcatttgtg cggccggtgc cgagtcgatc ggcctcctcg
   641581 ggagcacggg cggctacgcc tttctttcgc ggcgtgagcg acagcgcgcc gttgaggcgg
   641641 cgatcgagtg cgtcgacggc aggatacccg tcattgtcgg cgtcggcgcc ctcagaaccg
   641701 acgaggcaca ggcactcgcg cgcgatgcaa gaaaggccgg agcgagcggg cttctattgg
   641761 cccccatgtc ctatactccc ctgacggatg aggaggtttt gcagcatatt tccgctgtcg
   641821 cggaagcggg ccagctgccc ctttgcattt ataacaatcc gagcacgacc cgcttcacct
   641881 tcactgacga tctaatcgtc cgtctggcga ggctcccgaa cattgccgcc gtgaagatgc
   641941 cgcttcccgc gcaaggcgat gtcgcgggtg agctcgcgcg catgcgttcg cgcatccccg
   642001 aaggcttttc tatcggttac agtggcgatt ggggcgctgc cgacgcgttg ctcgcgggtt
   642061 gtgacgcctg gtacagcgtc gtcgcaggtc tcatgcctgc agaagccgtt gctctcacgc
   642121 gcgcggctcg agccggcgat gttgccgagg cccgtcgcct cgatcgggcc ttccagccct
   642181 tgtggaacct gttcaaggaa ttcggcagct tccgtgtcat gtacgccatg gccgacctgt
   642241 tgggccttgt cggagtcgac ccgccgcgcc cgatccttcc cctggggaag accgacatgg
   642301 cgagggtgaa ggatgctctc acccgcatcg cgctctgacg catcgtggtt cagggtctgc
   642361 tctcgccagc gaatgtggag acctcggccg ggtcggcgcc acgataatga ctcggcggct
   642421 ggccgatcac gcgcttgaag gcgcggctga aggaggcttc cgaatcatag ccgaggcgac
   642481 gtgccacgac cgagatacgc atgcggtcgc gggtcagcca ctgacgtgcc tggtgcatac
   642541 gcacttgcgc aaggtagcgg gccggcgtct cgccgaccac gctggcgaat tgctgagcga
   642601 agccggaacg cgaggcgccc atcagcctgg cgagggagtc gacggtccag gccttttccg
   642661 ggtcgaggtg catggccgcg atgacccggc cgaggccggg gtggcggacc gccgccaccc
   642721 agccgctggt attgccgcat ccgtgttcaa cccaggaacg gatgatgagg gccgcgagca
   642781 cgtcggcgag ccgcgccagg acaccgccgg aaccgacgcg gctggcgccg acttcccgcg
   642841 ccatggcgtc gagcatgtgc gggatagccg gctcgctggc ggtcagtgcg ttgattcgca
   642901 tcacgtccgg catcatgcgc agcagcggat gcatggaatc catgttgaac ctgaggctgc
   642961 cgcagaaaag aatggtggtc tcgccgcgcc cgccgccgca gacattgtag acgcaatggc
   643021 atacttcctg gaccgaatag gcgtcgagcg gagcgagttt ctcgcctggc atgcttgcca
   643081 gcgcgtgctc gccgccgcgc ggcaggagca cggcatcgcc gcgcttcaac tcgatccagt
   643141 ccccgtcggc gacgcgcagc cagcaatccc cgcagatgaa atggaagcgc gccgtctcct
   643201 gcgccggaaa tgagatcccc cagggtgccg tcaattcgca gcggacgtaa tccaccccgt
   643261 cgagacggag cccgcgcaac agctcggtca gaaaatcctc agaagcggaa gaggaggttt
   643321 tggacgaatg gtcaagcatt gcggaatatc tagcatggaa tgtccagggc gtcacgccct
   643381 atctaagccg gaccccatca tggagaccgc tcttatgaca gatacagcga ctaccctgga
   643441 tgccgcgctc ataccggaaa ccaacgagcg gatcgatccg gcctggtccg gtgtcggctc
   643501 acttgcgctc ggcgtgttcg gcctcgtaac cgcagaattc ctccccgtca gcatcctcac
   643561 cccgatggcg gccgatctcg gcatcagcac cggcacggcc ggccaggcgg tcacggctac
   643621 cgccgtcgtc ggcgcggtcg cgggactgac cgttgccatc gccacgcgcc ggttcgaccg
   643681 ccggctcgtg ctttgggggt ttactctcgc gctgattgtt tccagtctca tcgcagcttt
   643741 tgcgaccaac ctggcaatgc tccttaccgc acgggtcatt cttggcgttg ggctcggcgg
   643801 cttctggtcg atgatggcgg caatcgcctt gcgtctcgtg ccgatgtctc tcgtgccgcg
   643861 cgctatgtcg atcgtcttca ccggggtctc ggtggcaacg gtctgtgccg cgccgatcgg
   643921 cgcttacatc ggcgatctct ggggttggcg cgccgcattt ttgatggccg cggcagtcgg
   643981 cgccgtgacg ctgatcgtgc agatggtcag cataccccgg ctgccgccgc aatccgcccc
   644041 gagtttgaag cttctgttcg atctcctggg caggccgagc atccgtatcg ggatcatcac
   644101 ggttctgcta ttcgtctcgg gtcactttgc cggtttcacc tatgtgcgtc cgttcctgga
   644161 gaaagtgccg gaattcggta tcgaggcgat ctcgctgatc ctgctcgcct acggcatagg
   644221 cggcttcttc ggcaacatcg ccggcgggct catcatcgaa cgcagcatca cggcggccgt
   644281 tggtctcgca acgctgctta tcgcggccat ggcatttctc cttgtgacct tcggttcgct
   644341 ggatgtcgtt tcggccacgg cggtaaccat ctggggcttt gccttcggag ccttgccggt
   644401 cgccgtccag acctggatgg tgcgcgccgc tcccgaacat gcggaaagca caggcggcct
   644461 catcgtcgcg acattccagg tcggcatcgc cagcggcgcc gtgctcggcg ggctcttcgt
   644521 ggacgctttc ggcccgctcg gcgccatcac ctactgcgcc gccgcgacat ttgccagcgc
   644581 gctttatgtc gcgacttccc ggcggagcat cggtgtttga agcggagcat ttatagcggg
   644641 ccgtttccgt ggctgcactc aggcggtcgc gcgaactggt gacggaagct tcatctcatc
   644701 accacttcgg gcccgaagag cagccctatg attgctgcac atggaggctt gcgggcgcgg
   644761 aaggcgtgga cgaagtcatc tgtttatagg ttcctgccag gctgaggggc gatcccgtag
   644821 tgtggcgcgt gcagcttact tcggaagatt gtgattgcag ccttaacaag aaaaaaaccg
   644881 agctgcttac ctccgcctgt ctgttctttg gatccactcc ctcgtccgtg cttccggatc
   644941 ggcgttcagc gtgatgtcgg tcaccacggc ggcactgtcg gcaccatggg cgaaaacgcc
   645001 ttcgatacgc tcggggttga ggccgccgat cgcgacaagc ggcaggcggc ccatccggtc
   645061 gcgccaggtc gaaagccgct ccaggccctg cggcgcccat ttcattttct tgaggatggt
   645121 cgggtagatc ggcccgagcg caatatagtc gggcccggcc gcgagcgccg tttccagttc
   645181 cgcttcatca tgggtgctga ggcccagctt gagcccggcc gcgcggattg cgccgagatc
   645241 ggcgtccgcc aggtcctcct ggcccagatg gacgaagtcg caaccttcct cgatcgcgag
   645301 tctccaatag tcgttgacga tgagctggca ggcatgggcg gagcagaccg ccttggccag
   645361 gcgaatctga ctgcgaatat cgtccgcgcc gagatccttg acgcggagct gcaccagctt
   645421 gacgccgagc ggtaccaggc gttcgatcca ggcggcactg ttgacgatga gatagaaggg
   645481 gtcgagcttc acgagaaaac cgcctttccg ataacgggtg ttgagggaac ggccatgtcg
   645541 cggggctcca gcatgccggc gccatgggcg gcgtatcctg catcgatagc catggcgaag
   645601 gcttccgcca tcgcggcggg atcggcagcc cctgcaacgg ccgtgttgag caggaccgcg
   645661 tcgtagccga gttccatgac ggtcgtcgcg tgcgaagggc ggccgatgcc ggcgtcgacg
   645721 atcagcggca cgtcgggaaa ttccgcccgc atggcacgca ggccctgcat gttctgcggc
   645781 cccatggcgc tgccgatcgg cgcgcaccag ggcatcagta ccttgcaacc cgcctcgagc
   645841 agccgttcgg cgacgacgag gtcgtccgtc gtatagggga agacctcgaa gccttccccg
   645901 gtgaggatgc ccgcgccttc gacgagaccg aagacatcgg gctgcaacgt atcctggtga
   645961 ccaatcactt cgagcttgat ccagtccgtc tcaaaaacgt cgcgcgccat tttcgcggtc
   646021 aggacagcct cggcgaccga atggcagccc gccgtgttgg gcagcacacg cacgccgagt
   646081 tcgcggataa gctcgaagaa ggcgccgccc tgtcgcccgc ctgccgtctc gcggcgaagc
   646141 gacaccgtga cgatatccgt gcgtgaccgc cgcaccgctt cggcaagcac ggccggagag
   646201 ggatagcggg cggtgccgag caggagccgc gaccgaattt cggttccata gaacagcggc
   646261 acgttcaacc tccctgcatc ggcgacagga cttctatccg atcgctgtcc tgcagccggc
   646321 ggtcggcccg ctcggctttc tggacaagct cgccgttcac ggcggtcgcc agccagtcgc
   646381 cctcgaattc aaggtactgc agcagttcgg cgagtgtgtc ggcctggacc tcatgttcct
   646441 cgccattgat cgtaagtttc atcggacatc tcctctgggt atctctcgcc aagggccagc
   646501 gccgccacat ccccggccat ggccggggac aggaggaatc cgtggcgata gagaccgttg
   646561 acggtaatcg tgctctcgcg gcgcacggca cgcggcaggt tgtcggcaaa agccggtcgc
   646621 acgccggtgc ccgtctccac aaggcgggcc tcggcaaaag caggatggag cgcataggcg
   646681 gcgttcagca gctccatcag cgatcgggcg gtgatcggac cggcttcgtc gctctcgatc
   646741 atcgttgccc cgcacatgaa gagaccgccg ttgcgcggga cgatatagag cgggatccga
   646801 ggatgcagca tgcgcaccgg gcgagagagt gagacctcgt cggtcgcaag ataaagcatc
   646861 tcgcctcgca cgccccgcag cccgtcgatc ccgcctatcc ttgccgcacc ggtgcagtcg
   646921 acggtgagca cggccccgcg cccgtccggc tcttccgcca cgaaggtgac gccgcgcgcc
   646981 gccagtcttt gtcgcagcgc cgagagcgcc cggcgtggat cgaggtgcgc ctcgtccgga
   647041 aagaacagcg cctgccggaa gcggccggcg agcgccggtt ccagcgcccc gatctcctcc
   647101 gcgttaagcc agcgaaagcc gcaggtgcgg gccgcaaagc gcctgagttc ggctccgtcg
   647161 cgcggttggg cgacgacgag cgtgccgttg cgatggacgg aaccggcagg aagggcggct
   647221 tcccaccagt cggcggcgcc gatgccgcgc gtcaggacgg cttcctcggc gctttcccgt
   647281 tcgcaccacg gcgccagcat gccgccggca taccaggacg cggcccggcc aaagccctcg
   647341 gcattttcga tgacggttac ctcggcgccg cgcgccagaa gttcatgggc ggcggtgagg
   647401 ccggcaacgc cggcccccct gatcaggacg cgcatctcat tctccagtgg gcgcatcgct
   647461 cccatcgacc ggcatataga gatcgccgcc gtcgcggtat ttcgctgcca tcgcctcaag
   647521 gccctccttc tgcgcctcgg cacggatgtc gtgggaaatc cgcatcgaac agaatttcgg
   647581 accgcacatg gagcagaaat gcgcgacctt gtgcgcctcc ttcggcagcg tttcgtcatg
   647641 gaagttccgc gccgtctccg ggtcgagcga gagattgaac tgatcctccc agcggaactc
   647701 gaagcgcgcg cgcgacagtg catcgtcacg gatgcgcgcg gccggatgcc ccttggcgag
   647761 atcggcggca tgcgcggcga tcttgtaggt gatgacgccc atcttgacgt cgttgcggtc
   647821 gggaaggccc agatgctcct tcggcgtcac gtagcagagc atcgcggtgc cgaaccagcc
   647881 gatcatcgcc gcgccgatgc cggaggtgat gtggtcgtag cccggcgcga tatcggtggt
   647941 cagcggcccc agcgtgtaga aaggcgcttc gccgcaaacg gcaagctgct tgtccatgtt
   648001 ctccttgatc ttgtgcatcg gcacgtggcc ggggccttcg atcatcacct ggcaatccct
   648061 ggcccaggcg atctgcgtca actcgccgag cgtttcgagt tcggcgaact gcgcccggtc
   648121 gttggcgtcg gcgatagaac cgggccgcag accgtcgccc agcgaaaagg aaacgtcata
   648181 ggcgcggcag atgtcgcaga tctcctcgaa atgctcgtag aggaagctct cctggtggtg
   648241 atgcagacac cacttggcca tgatcgatcc gccgcgcgag acgatgccgg tgactcgatc
   648301 gacggtgagc gggatatagt ggagcctgac gccggcatga atggtgaaat agtctacgcc
   648361 ctgttccgcc tgttcgatta gcgtgtcgcg gaagacctcc caggaaaggt cctcggcaat
   648421 gccgttcacc ttttccagtg cctggtaaag cggtaccgtg ccgatcggca ccggcgaatt
   648481 gcggatgatc cattcgcgga tattgtggat gttgcggccg gtggaaaggt ccatgaccgt
   648541 atcggcgccc cagcgggtcg cccataccat cttctcgact tcctcggcca tcgaggaagt
   648601 cacggcggaa ttgccgatat tcgcgttgat cttcaccaga aagttgcggc cgatgatcat
   648661 cggctccgac tccggatggt tgatgttggc cggaatgatg gcccggccgg cggccacctc
   648721 ctggcggacg aattccggcg tgacgaaatc ggggaccgat gcgccgaagc tctcgccatc
   648781 gcgcgtgagt acctccttcg cggctttgcg gccgagattt tcgcggatgg cgatgaactc
   648841 catttccggt gtgatgatgc cggcgcgggc aaaggcgatc tgggtgaccg cttgtcccgg
   648901 cttggcgcga agcggctgat tgcgcaccgg gaattccggc gtgaggcgct cgccgctcgc
   648961 aaagccgttg tcttccgcct tgaccgctcg gccctcgtaa ctttccacgc cgccgcgctt
   649021 caggatccag tcgtggcgca gacgcggcag tcctgcgtcg atgcggatat cggcattctc
   649081 aagcgtgtag ggtccggagg cgtcgtatac ggtcaccggc ggttcgcccg aggtcggatg
   649141 cagggtgatc tcgcgcatcg gcacgcggat gtcgggatgg atatcgcccg gcctgtagac
   649201 cttttgggac gcggggagcg gcccttgggt gaccgaaggg gtcgcgccga gaggcttgaa
   649261 tagattcata atgaggctcc aaagttttcg cgttggagac ccagttctga agccggaatg
   649321 atggaaagac gcattgccga cggatcgcgg gactacggga tcctggctgt cgcacgtctg
   649381 caccgtccct acgccagtat gaactggatc aggttcaacg ggtcactgcg cgctatagca
   649441 gtatctcagc cccttgccgg gacccccctg gtgaatggcg taattaggga cggtaatcga
   649501 cgcggcgtca agatggtttc tgatgcccgg ccacgatcgg atggcgagca tgggagaagt
   649561 caaaggaaaa ccatgcgcat acctcccgtc atgcttgcaa gcggagcgct ttgcctctaa
   649621 ccacgcgcca cgaacactag gcgtcataag acgcgtaacg aaggggcgaa aatcgtgggg
   649681 caggcggaga ccagaaccgg gaaaagggcg gcgctttggg ccgccgtcgc gttgattgca
   649741 atcgcagccg cgggcatgac cggctacaag atcgtcgccg aaaggaccat gagcgggatg
   649801 atcgccgaaa ggggcggcaa ggttggcaat gtcgaagcgg attttctggg gcgcattcat
   649861 ctgcgcgacg tgaagctgcc tctcaaggac gggtccgaag ttcatatcgc cgcgattgac
   649921 gggcgaccgg agatcttctt cctgaaaggc atgctcgaag tagcagggct ccaactcaag
   649981 accaagctgg gcagcgtcga agtcccgcag gcgaccgtcc aggaggcaaa tctcagctat
   650041 ggcacgacga cggagatctt cggcgggcgc ggcgatctgc cgttgtcgaa gcgaatagag
   650101 ctttttgcgg cgcggcgcgt cgttgctccg gagatcctcg tcacccagac cgtcggcggg
   650161 agcgagcaga agctcgtcta caggaacgtg gtgtcggaag gcatcgccga tgggcgcgtg
   650221 tcccgctttt cggcggaggg cgccagcttc gagttcggcg tggacggcaa cggcggagag
   650281 gccggcggga agaagcgcct gaccggctcc cttggaccga tgaccgtgca ggatatggat
   650341 gcggcctacc tggcgcggct atataccgag aaggccggcc cgcaggacaa ggaggcaaag
   650401 ccggtttacg gaccgagctc ggttaaggac atcgtgtttt cggacggcga ggcgcgcttc
   650461 ggctacgccg agattcgcag cagtggtatc agcatggcca tgacggacca accgctgctc
   650521 gagacgctga atgcgttgag cgcggtttct gcgcccgatg aattgcctcc tgcggagcgc
   650581 caggcctatt tcacccggat tctgtcgatc atcgacatga caaaaaaggc cgacatcgaa
   650641 atgctcggcc tgaacatgga ggtgccggcg aaggacggcg acaaaggcaa gaagatcaag
   650701 tttgccacgg atcgcctcgc cattcagttg gatggccaga cgcttgacgc cacattgaac
   650761 ggcctctcga tggcggaagg tgagagccat ttcaaaatct ccgaagcggc cctttccggc
   650821 ttttcctgga gccccacttt caaagctctg gaacagatgg tggcccttga cgagcagcag
   650881 cttgagagct tccctttcac gaccctgttg cccgaattcg gcacggtaag gctggcgggc
   650941 attgatgccg acctgccggg ttcagtggag aacggcgaaa catcgccttc gactgcggag
   651001 cgcgtccgct tctcactcaa ggaatatgaa gcggcgctca ccaagccgcg caacggtata
   651061 cccaccgaca tccgcgtcag ctaccaggat ctgaccgttc cggtccccgc gaacatcgag
   651121 gaaaagacgc tggccgagct tcgcaagctg ggcatcgacg aactggttct ttcttccagt
   651181 ctcgaagcgg cctgggacga ggcgcagcag acactcgtca tcaaggagat ctccacgagc
   651241 ttgaaagacc ttgccggctt ttccttctcc ggcgtgatgg ggggcgtgag cggcgatttc
   651301 ttttcgggtg acgaggcgaa gatgcgcgtg gcgctctttg gcctcaccgc acgggaggcg
   651361 gagcttgaga tcgaggacaa gggcctcgcc gccaagggac tgaaggctta tgccgaacaa
   651421 aacggcatga cggaggatca ggcgcgtggc atgctgacga tgacgtcgtc ggtggtcttg
   651481 cagcaattcg cggacgagga gcctcggttg caggacgtgg tggacgcggt ttcgaagttc
   651541 atcgccaaac cggggacatt caccctgacg gtcaagtcca aatcgccaag cggcctgggg
   651601 gcgctggaac tcgcggtcgc ttcgcaaaat ccgctcctgc tcctcgatag ggtcgatatc
   651661 gaggccgtgg cggaatagat cacgatgctt ttgggtcgga tcgccctaaa aacatgaacg
   651721 tgatcaattc caaagagctg aaacgcggga tgcgggcgga aaaccgcaca cagttttcct
   651781 catcccgctc caggcgccgc ttccggtttc acgatccgct caggcggggc ctcgttcttt
   651841 gacatagtcc gtccggttga tgccgtggcg ctgcagcttg tcgtaaaagg ttttacgggg
   651901 gatgccgagg gcccgcagcg tttccctgac gtcgccgcga tgggctgtca gcgcttcctt
   651961 taggatattc gcttcatagc gttccagcct ttccggcagc gtcgcaccgc ctgaaacggg
   652021 tgcggccgcg gcggcgccca gagtgccctc taccccaagg gccacccgct cggcgaaatg
   652081 ggaaagctcg cgcacgttcc ccggccagga atgcgctgcc aggtgatcgc gcaccgcgga
   652141 tgggatcgcc ggcacatcgc ggccgaagcg ctcggcggca cgtgcgagga aatgggagaa
   652201 gaggagcgga atgtcgtcgc ggcgttcgcg aaggggtggg atcgagagcg ttaccacgtt
   652261 cagccggtag aagagatcct cgcggaagtc gccgcgttcg gctgggtcgc cgagatcgac
   652321 cttggcggcg gcgacgacgc ggatgtcgac cgggcgtgtc agatttgtgc cgagcggcgt
   652381 gatctcgcgg gcttcgagca cgcgcagcat cttcacctgc gttgccggtg gcatagcctc
   652441 gatttcgtcg agaaagagcg tgccgccgct tgcatgctcg atccggccga tacgcttctt
   652501 gacggcgccg gtaaacgccc cgggctcgtg gccgaagagc tcgctctcga tcaccgtttc
   652561 cggcagagcg ccgcaattga gggcaacgaa attgccgctc ctgcgccggc tccagtggtg
   652621 cagcagcgtc gccacgacct ccttgccact gcccgtctcg ccggcgacca gcacgtcgac
   652681 atcggtatcg gcgatgtgct tcagggtctg gcgcagccgc tccatcgccg gcgtctgacc
   652741 gatcagcggc aggccctcgg aggcggcttc ggccgtgcgg cgaagcgcac ggatttccat
   652801 gacgagccgc cgtttctcct cggcacgcct tgcgctctga acgagccggt cggcggcaaa
   652861 gggtttggcg atgaaatcat aggcgccgtc ctggatcgcc tgcaccgcca tcggtatgtc
   652921 gccgtgcccg gtaacaagga tcatgggcag atccgggtcc agcgccagaa ccttgcggaa
   652981 cagcgtaagc ccgtccatcc ccggcatgcg gatatcgctg atgacgacgc ccgcgaagtc
   653041 ggcggtgagt tctccgagcg cctccgccgc gctggcaaag ggcgagacgg tgaagcctgc
   653101 aagctccagt gtctgctgca tcgccttgcg aagatcgcgg tcgtcatcga tcaggaacac
   653161 ggttggagct gctctcatcg ctcatgcctt catgagattt acgataaatg tcgttccgga
   653221 cgggctgctc gcgacctcga tcgtgccgcc atagtcggag acgatctcct tggagattgc
   653281 caggccgaga ccaagcccgt cttccttcga ggtgttgaag ggcgtgaaca gctcttcgcg
   653341 gacatcggcc ggaatccccg gaccgttgtc ggcgacggtg agcgttacgg cggtggccgt
   653401 ttcctcgcac gacactttga tcgcgccatt cccgctgtcg ccgatcgcct cgagcgcgtt
   653461 ctgcagcagg ttgatcagga cctgctccag ccggatgcga ttgccgaata cctgaaggcc
   653521 atccggcggc agatcgatgc ggattgcgtc catccgcccg gcaaaacggc tgcggagcag
   653581 catgagcgct ccctcgatca catccttcat cgcggtcggc ccggcggcga aatgaccctt
   653641 gcgggcgaag cgacgaagtt cgtcggtaat ggcgccgacg cgctcggtga gttcggcgat
   653701 gctctccatg ttttcggctg cggtggcgct ctgaccgcgc tcgagaaatg tgcgggcatt
   653761 gtccgcatag gcgcggatgg tggcgacagg ctggttgatc tcatgggcga cgccggctgc
   653821 gacctggccg aggatcgcca gccggtttgc ctggacgagg tcctgctgga ctgcctgcaa
   653881 tttctcggtg gtctggcggt gatcggcgat ttcggtttcg agccggtcgc gtgccatgcg
   653941 gagatcgcgc gtccgttcct cgacgcttgt ctcgagtttg ctgcgggcga gccgctcctc
   654001 ggcgctgcgc atggcgatca cctggcgccg gcgcaggagg tatgccgcca gccccagaag
   654061 cggcaccagc gcggcaagcg tgatgagctg cgcttcgcgt gctccggcgg caagcggcgc
   654121 tttcagcggc gacaattgct cgaggcgcca gttcgtcgac ggcaccattg tctcgacgcg
   654181 cagaaaggct gcgttcgcct cgcccggcag cagggcgtcg agggtggagg agccatcggg
   654241 ccgcgcctcg accttgcgga aggggagcgg caacagcggt gcgtcaccga attgcaggct
   654301 ttcacgaatt ggggcaaggc gctcccgcgc gatcggcttg gtcgtcatga agcgccagga
   654361 gggcatgctg gtgatgagga cgatgccgcg ccggtcggtg acataggccg gcttgccgga
   654421 ggcctgccaa tccgcctcga ctccgtcgaa ttcgagcttg gcaacgatca cccccagcgg
   654481 gccaccgggc ccagcgacgc gacgggagat atagagcccg ggccgtttgc ttactgtgcc
   654541 catggcgaaa tgctcggcca tgccgtcgcg catggcgagc cggaaataat cgcggaaggc
   654601 ataatcgttt ccgacgaagc tggtggaatc ccgccaattg ctggcggcga tggcggtgcc
   654661 gttccggtcg atgaggtaga tgaccgccgc ttcggcgctc gtcgccaaac cttcgagctt
   654721 gcggttgatc cggtccagcg attgccgatc cggggtaagc agcgcgccac gaatggccgc
   654781 gtcgtcggcg agaaccagcg gaagggcgcg ctgccgctcc acgaccgccc ggagaagcga
   654841 ggctttgagg ctggcgtcga tccggctttg accggcaagg ctgaagaggg cccgtgaccg
   654901 cccgtagtcg cgggcaaaaa ggaggccggc agcgacgagg accagggcga cggccgcaaa
   654961 cacgagccag gatcgacggg cgcggctgcg aagcgccgcc ggatcttcca tgtctgcgtg
   655021 tttgctcatg ccggtattgt gcatattttc gctcaagccg ccagagatcc tgtgcggaaa
   655081 tccgcacaga cactcggtag agcgcgaggc cctgtcgtgg aaagcttcat caattcaatt
   655141 gcatggcgct ttcccggcaa actggcacgc atgttgctgg ccagctccac aggcagccgt
   655201 tgctgtcgat cttcggaaag cggcccggga ggcccggcat gttgccggac tgggcctgtc
   655261 acgtggagga catcatgatc atcgaacatt ccgctgaggt ccgcggcaag acgccccttt
   655321 atcgccatct ctacgtccag gtgctggcgg cgattgccgc gggcattctg ctcggccatt
   655381 tctatcccga tatcgggacg cagctcaaac cgctcggcga cgccttcatc aggctggtca
   655441 agatgatcat tgcgccggtg atcttcctga cggtggcgac cggtattgcc gggatgaccg
   655501 atctggccaa ggtcggccgc gtcgccggca aggccatgat ctacttcctg gcattctcca
   655561 ctctcgcgct tctcgtcggc ctcgtcgtcg ccaatctcgt gcagccgggc gccggcatgc
   655621 atatcgatcc ggcttcgctg gatgcgaagg cggtcgcgac ctatgcccag aaagcacatg
   655681 agcagtcgat caccggtttc ctgatgaaca tcattccgac gacgctcgtc ggggccttcg
   655741 ccgaggggga cattctgcag gtcctgttca tttcggtgct cttcggcatc tcgctggcga
   655801 tcgtcggcaa gaaggccgag cccgtcgtcg atttcctgca ggccctgacg cttccgatct
   655861 tccgattggt ggctatcctg atgaaggcgg ccccgatcgg tgctttcggc gccatggcct
   655921 tcaccattgg caagtacggc atcgcctcga tcgccaacct cgccatgctg atcggcacct
   655981 tctatctgac gtcgttcctc ttcgtcttcg tcgtgctcgg cgcggtggcg cgctataacg
   656041 gcttctcgat cctctcgctc gtgcgctaca tcaaggagga actgctgctg gtgctcggga
   656101 catcctcctc ggaggcggct cttccgggcc tcatgaacaa gatggagaag gccggctgca
   656161 aacgctcggt cgtcggtctc gtcattccga ccggctattc cttcaacctg gacggcacca
   656221 atatctacat gacgcttgcg gccctcttca tcgcccaggc gaccgatacg ccgctctcat
   656281 acggcgacca gatcctgctg ctcctcgtcg cgatgctgag ttcgaagggt gcagccggca
   656341 tcaccggcgc gggcttcatc acacttgccg caacgctctc ggtcgttccc tccgtgccgg
   656401 tggccggcat ggcgctgatc ctcggcatcg accgcttcat gtcggagtgc cgggcgctca
   656461 ccaacttcgt cggcaacgcg gttgcgacga tcgtggtggc gaagtgggaa ggcgagcttg
   656521 atcaggcgca gctttccgcc gcgcttggcg gcgaaatgca ggttgaaacc attcctgcgg
   656581 tcgtcgttca gcccgccgag taaacttgca tcttgaggcg agactgcacg ctggtgcggt
   656641 tggcgcggtc tggttttctc caggccgcgc ttttgcgggc cgcctgccga tcaaatcaaa
   656701 tcccgtgcag cacctgggtc gccttgacgg cggcggacgc ccggttttca acgccgagct
   656761 tcacgtagat ctgttcgaga tgcttggtga cggtgcgcga gctcagtccg agaatctctc
   656821 cgatgtcccg gttggatttt cccttggcaa tccacagcag cacctcggac tcgcgcgggg
   656881 taagctggaa atgctggcgc agggtttcgt cgtcgctcat gccgttctcg gtcgtcaggc
   656941 ggaagagaaa ttcgttggcg ccgatcgccc cgagatagga gatctgcaag ccggtctgcg
   657001 ctgcgcgctg cagggtgaaa ctcccgtgcc tttctccggt gcctttttcc ctttcccgca
   657061 tccattcggc gatacgcccg gcgacgaaga agagaccgtc gtcgctgccc gtggcagcgt
   657121 tgacgaggcg ggtcgcctgc ggcgtagacc agcgcaccgt gccatcgccg cgcacggcca
   657181 gcagatgccg gccggcagcg tcgagtgcga cgcgggcgct ctgcgcggag cgcgcattgg
   657241 aaaggtggac gcgtatgcgg gcgcgcaact cgtcgatatt gatcggcttg gtgagataat
   657301 cgacaccgcc ggattcaagc gcccgcacca cgtgctccgt ctcggtgagg ccggtcatga
   657361 aaaccaccgg gacctgggcg accgacgcat tcgccttcaa ccgcgcgcaa gtgtcaaagc
   657421 cgtccatgcc gggcatgacg gcgtcgagca ggatgatatc cggcgtgatg cgatcggcga
   657481 tgttgagcgc cgcattgccg gaggtggcga tcagaacgga gaagccggac tgttccagtg
   657541 cctcggtcag gaagccgagg gcctccggtg aatcgtcgac gaggagaacg atgtcgcggg
   657601 cgttcgctgc ctcaggcacg ggcattcgcc tccccggcga gcaggcgttt cagaaaagcg
   657661 tcgtaacccg aaaggtcgaa tgcctggaca taggcgcgcg cttcctcggc gaaggctcgg
   657721 ttatccgggt tcagggcgat ctccgtcagt ttcgcttcga tgcccctcac gtagccgatt
   657781 tcgccgagtt cgatcaattc ccggatgtga tgattgccgg ggcttatgac tgcaccggcc
   657841 ttgtccggtc cacgcgtttc cttgggcccg tcgtcgtaga tccattcgag gccgagctga
   657901 atcgcgagct tgtcggtgag ctggcggaca cggaagggtt tggcaagcgt atcgttatgg
   657961 ccgaaggcgc cggcagccga accgtcgccg atattggccg aaagcatgat tgccggcgct
   658021 gtctggccgg cctccctcag ccgcgtcacc aagtcccagc cgttcattcc gggcatggat
   658081 atgtcgatca ggaacagatc cggtttcgtg tcttcgatga gcgtcaggca atccgctccg
   658141 ctcgccgcgg ggatgacggt gaaatcgagc ggcgtcagta cttcgcgcat cagctcgcgg
   658201 tgctcgggat tgtcgtcgac cacgacgatc gcgcggtgcg gtccctggta ggacctgatc
   658261 ttgcgcaccg cgtccttgcg cgcggccgga cggtctactg cggagagcat aagccgcacc
   658321 ttgaagaccg tgcccttatc cctctcgctg gtgacggaga tttcgccacc gagcgtctgg
   658381 gtgagaaggc gcgtgatcgt caggcccagg ccgaggcccg gcatgcgata ttccgcttcg
   658441 ccgcgctgga atggttcgaa gatcttcggc agatccctct cgctgatgcc gcggccgctg
   658501 tcttcgaccg taaaactcgc gacctgactg cgataagcga cgtcgaagcg gatgtggccc
   658561 cgttccgtga acttcaaggc attggaaagc agattgacga ggatctgccg caggcgcttg
   658621 tcgtccgttc gcacatattg cggcagcgcc gccgcgcggc tgtgttcgaa ggtgatcccc
   658681 ttggcctgcg cctgcggacg gaacatgtcg acgatctggt cgaggaaatc ctggatattg
   658741 atctcgttgg aatagacctg cagcttgccg gcttcgatct tggatatgtc gagcagccca
   658801 tcgatcagtc cggagagatg gtcggcgctg cgcctgatcg ctttgattgc gttctgtcgc
   658861 gacggcggta tcgtctcgtc gcgttcgagg atctgggcgt agccgagcac cgcattgagc
   658921 ggcgttcgca actcgtgact cagccccacg acatagcggc tcttcgcacg gttggccgcc
   658981 tccgcccgct ctttcgcgtc ctgcagtgcc gcgtcggtct tcttgtgggc cgctatctcc
   659041 ttcaggagag ccgtgttctg ccgcgaggat tcttcttccg cgacgacacg gctgtcatgg
   659101 gcaagcacgt agaaccagga cacgatgccg gcgaggatgg cgaaaacaaa aaagacgatg
   659161 gcaacggtac gctcgaccac ggcggcggtt tcgggagaag cggcggtagt ctggtgcgcg
   659221 atcatcgcga ggatcgctcc gataccggtg atggagatca ccgccgcgat ggcgtagcgg
   659281 ccgagccgcg tcgcaagttt tgcgacgacc gtttcgggca gcagtgcctt ggctacagtc
   659341 gcgatctgaa agctcagtcg cgccttcggt ttgcacatgt catggcagcg gccgtcgagc
   659401 gagcagcaga gcgaacagat cggcgccgca taagccgggc accaggccat gtcctccggt
   659461 tcgaacgggt gctcgcagat tgagcaggtg atctcgctct cggagaacca gctcttgcgc
   659521 ggcttgcggg caaggtagaa tttcccctcc gtccaccagg cgatcagcgg cgagacgagg
   659581 aaggccgtgg cgagcgcgat aaagggagcg agcgagcttg cgatctcgcc catcgcgccg
   659641 aaatgcgcga ccagagcgaa cagcgtcgac acgcccatgg tgccgagccc gacgggattg
   659701 atgtcataga gatgggcgcg tttgaactcg atgccggccg gcgccaggcc gagcggcttg
   659761 ttgacgaaca aatcggccga gatcgtgcag agccaggcca tggcaatgat cgaaaagatg
   659821 ccgagcgtct cctcgagaag ccgatagatg ccaagttcca tcaggaggag tgcgatcgcc
   659881 acgttgaaga ccagccagat cacccggccc ggatggctgt gggtgaggcg cgaaaagaag
   659941 ttcgaccagg cgagcgaccc ggcataggcg ttcatcacgt tgatcttgag ctgtgaaacg
   660001 acgacgaagg ctgccatcag caggagggct gccgtctcgt atgggacgat atagccgaag
   660061 gccgtgtagt acatttgcgc cggatctgcg gctctggtgg aaggcacgcc ggcgctgagc
   660121 gccaggacga ccaggaagga tccggcaagc agcttcggcg cgccgacgat gacccagccg
   660181 gagccggcga gaaagaccgc tatgcggtgg cggagcttcc gctgaccgtc gggcggcaga
   660241 aagcgcagga aatccacctg ttcgccgatc tgcgccatca gcgcgaagat gaccgcggaa
   660301 gccgcgccga actcgatgag atcgaagggc gcgacggtgc cggagggacc cgaagtgtga
   660361 tgaatgcccg cataggcgag ccacaggccc accttctccc agtccgcgag cgcgatgaag
   660421 gcgaagggaa ggatgttcaa cacgatccag aagggctgcg tgacgagctg aaaccggctg
   660481 atcagtcgga cgccatgggt gaccagcggg atcaccacga cggcgctgac gatgtagccg
   660541 gcccagagcg ggaccccgag cgccagctcc agcgcgccgg acatgatcga ggcttctatt
   660601 gcgaagagga tgaaggtgaa gctcgcatag atgagcgagg ttatcgtcga gccgatatag
   660661 ccgaagctcg cgccgcgcgt cagaaggtct atgtcgacgc catggcggat ggcatagcgg
   660721 ctgatcggca ggccgacgat aaggatcatc aggcttgcga cgaggatcgc gacgatcgcg
   660781 ttggtggtgc cgtaggacat ggtgatggcg ccgccgatag cttccagcgc caggaatgag
   660841 atcgcgccga tcgccgtctg tgaaatgcgc gcggaggaga agcgccgcgc gctctttgcg
   660901 gtaaagcgca gcgcatagtc ttcgagcgtc tggtcggcga cccagcgatt atattctctt
   660961 cgaacgggaa tgatgcgctg gcgtgccgcc atggtccctc gtcatctcgc agcgccggtc
   661021 aattgccggc cgctcatgtc gtaacacgga cgtgcggcgc gaagcacgtc ctattgtcgg
   661081 cggaaacgag ttcgctgcag tgtgtcacgg cgtgtgccgt ctgatcgttt tgatcgaata
   661141 gtatcgagtg ctctccgtgt gaggacggtt gcgctcctga gtcccttgag attgacggga
   661201 ggactgggga aacctgccgg gcagaggaga tcaaacagtc aagtaacagc gacatgcgag
   661261 aaatcctttc aatactctgc caacagggcg tggtgagtgt ggaagagctg cgccgttgca
   661321 tgccaggcgc tctgcggcga ccgcgccgtc acttaacggc tgcccttgac agaattgccc
   661381 tctgctgcaa taaaccgaaa agttaattaa cctatcggtt aaggatatgg acccgctcag
   661441 cagcaccttg tcggcattgg ccgatccgac ccgtcgtgcc atcattgctc gtcttgccgc
   661501 cggcgaggcg acggtgaacg aacttgcagc gcctttcgac atgagcctgc cggcggtttc
   661561 caagcatctg aaggtattgg aacgcgcggg actgatttcg cgcgggcgca acgcccagtg
   661621 gcggccctgc cggctagagg cagcgccgtt gaagggaatt gccgattgga tcgaacgata
   661681 ccgtgatttc tggacgcatg gcttcgatcg actggacagc tatcttgatg aactgcagcg
   661741 caacgagaag tcggatcacg agtgaatcgg gttcgcgcaa ccgcaaggag aagacaatga
   661801 atgcatcgtc tctgaaggag gagaacgctc ttaccattac gcgcgtcgtc aacgcgccgc
   661861 gtgatctcgt cttcaaggtc tggaccacac aggaacacct ttcgcgttgg tgggggccga
   661921 aagacttcac cgttgctgcg atgacgacgg atttccgtag gggcggcgcc tggcgttgtt
   661981 gcatccgcgc gccggaggga caggactact gggcgcacgg catctatcgc gagatcgagc
   662041 agccaaatcg aatcgtcttc agtttcgcct gggaagagga aggcgccatc gacacgctga
   662101 ttacggttac cttcgaggat gtgtcgggtg gcacagctct caccttccat cagacgccgt
   662161 tcacgagcgt cgagagccgc gattcgcacg cggagggctg gagcgagtgc atcgatcggc
   662221 ttgccgacta tgtcgctgcc cggaaggagg aagtgcaatg aagaaggctt atcacggaag
   662281 ctgccactgc ggcgcggtgc gcttctccgc gaacctcgat ctcgcgcccg agggaaaacg
   662341 ctccacggcg ccgcggccgg gcgtatggtg gacgacaacc ttccgctgca attgctcctc
   662401 ctgcctgaag acgcgcttct ggaaagtgtt cgtcacgcct gaggactttt cgttgctttc
   662461 cggcgaagag gctttggcgg aataccgttt cggcgagcgc atgatccggc acgtgttctg
   662521 ccgccactgc ggcgtccatc cgtttgccag cgccgatttc gaaatcctgg gagggccgtt
   662581 ccacgcagtc aatataacct gtctcgacga cgcgacagac gaggaactgg cgagtgcccc
   662641 agtggtctat gaagacggcc ggcacgatgc ctgggaccgc tcgccggcgg tgaccggcta
   662701 tttgtaaggc ggcgcaccgg gcagcgtctg ccgcggagcg atccggatcc gcggcggaaa
   662761 caatcgccgg tcgaagtcca gcttccttct tcccccccaa cgcctacgta gaatgacgta
   662821 tgtgcagtgc aacgtgactg cccgatgatc cctcaagcaa ccgccaagca aaacaaacac
   662881 tcggttgcag cgaccagaac tagaggggat caatcatatg actatcaggg cacgcgtcac
   662941 aggcgcattc ctagccgccg tcctttcgac gaccgcgttc aacggcgcct tcgcggcgga
   663001 ggacacgatc aaggtcggca tcctgcactc gctttcggga accatggcga tatccgaaac
   663061 gacgctcaaa gacgcaatgc tgatgctgat cgaggagcag aacaagaagg gcggcgtgct
   663121 cggcaagaag cttgaagcgg tcgtagtcga tccggcctcg gactggccgc tcttcgccga
   663181 gaaggcccgt gagctcgttt ccgtcaacaa ggtctccgcc gtcttcggct gctggacatc
   663241 ggtgtcgcgc aaatccgtat tgccggtctt cgaagagctg aactcgatcc tcttctatcc
   663301 cgtccagtac gaaggcgaag agagccagcg caacgtcttc tacacgggcg ccgctcctaa
   663361 tcagcaggcg atccccgcgg tggactacct gatggaaaac gaggaagtcg agcgctgggt
   663421 gctcgccggt accgactatg tctatccgcg cacgacaaac aagatcctcg aggcctacct
   663481 catctcaaag ggcgtcaagc ctgaggacat catgatcaac tacacgccat tcggtcattc
   663541 cgactggcag acgatcgtct ccgatatcaa gaagttcggc tccgccggga agaagacggc
   663601 ggtcgtctcg acgatcaacg gcgacgccaa tgtgcccttc tacaaggagc tcgcgaacca
   663661 gggcgtcaaa gccgaggaca tcccggtcgt ggccttctcg gtcggcgagg aggagcttgc
   663721 gggcctcgat accggtccgc tcgtcgggca tcttgccgcg tggaactatt tccagtcggt
   663781 cgacagtccg gccaatgccg cgttcatcga aacctggaag gcttatacca aaaacgacaa
   663841 gcgggtcaca aacgacccga tggaagccca ttatatcggc ttcaacatgt ggctgaaggc
   663901 agtcgagaag gctgggacca ccgacacgga tgccgtgctc gacgcgatga tcggcgtgtc
   663961 ggtgccgaac ctttcgggcg gttattccac catgatgccg aaccaccata tcaccaagcc
   664021 ggtgctgatc ggcgagatcc agtctgacgg ccagttcgaa acagtctggg aaacgcccgg
   664081 cctcgtcctc ggcgacgaat ggtcggacta tctgccggac tcgaaggacc tgatttccga
   664141 ttggcgcgcg cccatgtcat gcggcaactt caatgttgcc acaggaaagt gcggcggcaa
   664201 aggttcctga ttttatcacg aaagactttt caggcgagcg gcccaggtcg ggccgcatcc
   664261 cactccattt catgatgagc cgccagctgg aattaccctc cgtccgggac ttttcttcgg
   664321 acggaggact ccaagagtga gaaacgcatg taccgcatca tccaaaccgt tctggccatg
   664381 ttgttccttt tcgccgcgat gccgcagggt cttcgcgcag cagagggact gcgcaatctg
   664441 gtgaacgcgc tcggcgaggc gaaactttcc gcgatggatg agcatatagc cgccctggca
   664501 aagaccggag agcctgaagt cgtcgcgatt ctcgatgcgc tcggcgcggg caacctctat
   664561 gcccgcaaga cagacggcca ggtctttctc accaaagaga gcggttcgaa ccttgcactc
   664621 atcgacccta tctcaggcga aagcgccggc gaaacgccca aggcggcgat gtcgaagatc
   664681 aaggtgaaca acagcgtgcg ccgcgccgtt cgcgcggccc ttggcggttt gacgctgctc
   664741 agccccgatc gcgctcagcg cctcaaggcc gcgcaatccg tgctgcaaac gccggatgtc
   664801 gacgcgcttg acgccgtcga aaatgcgctg gttgccgaga aggacgaagc cgttcgcacg
   664861 gtccttgaac aggcgcgcgc ggcgatgctg cttgcttccg accggccgat tgaagagaag
   664921 aaggaggcgg tgcggctgct tagggaaaac ggcggccgcg aggcgttgcc ggtcctttcc
   664981 gctgcactcg gttccgccga gaacggcctt gagcaggata tcgaggcagc catcgccagc
   665041 atagaacagg cgcaagagtt ctggaatgca ggccagaacg tctggtacgg actttcgctc
   665101 ggctctgtgc tgctgcttgc ggcgatcggg cttgcaatca ccttcggcgt catgggcatc
   665161 atcaacatgg cgcatggcga gatggtgatg ctcggtgcct atacgacctt cctcgttcag
   665221 gatgtcgtac ggacctcctt tccccacctc ttcgagtggt cactggcgat cgcgctgccg
   665281 ctcgcctttt tattcaccgg caccgtgggt ctcgtgcttg agcgcggtgt cattcgcttc
   665341 ctttacgggc gtccgctcga aacgctgctc gctacctggg gcatatcgct gatcctgcag
   665401 cagtcggtgc ggacgatctt cggacccacc aaccgcgaag tcggcaaccc cttctggatg
   665461 tccggcgctt tcgagctcgg aggactgacg attacctgga accgcctctg gattatcgtc
   665521 ttcgcgctgg ccgtcttcgc cgcgctcctg ttcctcctca agaagacgcc gatgggcctg
   665581 cagatgcgcg ccgtgacgca gaaccggcgc atggcctcct cgatgggcat ccgaacgcct
   665641 ctcgttgatg cgctcacctt cgcactcggt tccggtatcg cgggcatcgc gggcgtcgca
   665701 ctttcgcaga tcgacaatgt ttcgccgaac ctcgggcagg gttacatcat cgacagcttc
   665761 atggtcgtgg ttttcggtgg ggtcggcaat ctctggggca cgctcgtcgg agcattttcg
   665821 ctgggcatcc tcaacaagtt cctcgagcct tatgccggag ccgtgctcgg caagatattg
   665881 gtgctcgtgc tgatcatcct cttcattcag aagcggccgc gcgggctctt cgcactcaag
   665941 ggccgggcgg tggaagcatg atcacctcgt ttctcgtcaa atctctcgat cggacgatcg
   666001 ccgtcgctgt cgcgatcctg cttttgctgg ccgtcattgt tcccgcgctc aatctcctga
   666061 ccgcaccgga ccacccgctt cacgtgccga cctatatggt ctcgctcttc ggcaaatacc
   666121 tgacctatgc gctcctggcg ctggcgctcg atctcgtctg gggtttctgc ggtatcctct
   666181 cgctcgggca cgctgccttc ttcgcccttg gcggctatgc catgggcatg tatctgatgc
   666241 gtcagatcgg cgcgcgcggc tcctacggca acccgcttct gccggacttc atggtgttcc
   666301 tcaattggaa ggaactaccc tggttctggt acggcttcga catgttctgg ttcgcggcgc
   666361 tgatggtcat cctggtgccg ggcctcgtgg ccttcgtctt cggctggttc gcgttccgct
   666421 cgcgcgtcaa cggcgtctat ctttcgatca tcacccaagc gatgacctac gcgctgctgc
   666481 tcgccttctt ccgcaacgac atgggcttcg gcggcaataa cggtctgacg gacttcaagg
   666541 acattctcgg cttcaacata caggcggacg gcacgcgtgc cgcgctcttt gccgcctccg
   666601 cactggcgct cgccggttcg ctcgtcgtta cctcgggaat cgtcggttcg aaattcggaa
   666661 aggtccttgt ggctctgcgc gatgcggaaa gccgcacacg gtttctgggc tatcgagtcg
   666721 agcacatgaa gctcttcgcc ttcaccgtct cggcgatgat ggcgggtatc gccggtgcgc
   666781 tctacgtgcc gcaggtaggc atcatcaacc caggggagtt cgcgcccgcc aattcgatcg
   666841 aggtggtcat atggactgcc gtcggcgggc gcggcacgct gatcgggccg atcgtcggcg
   666901 caatcctcgt caatggcggc aagagcattt tcaccgccgc ctttccggaa ttctggcttt
   666961 tcgcgcttgg cgggctcttc gtgctcgtta ccctgttcct gccgaagggc gtggtcggga
   667021 ccgcccagca ccatctcgcg cgacgtcgcc aagcccgcgc tgcggcccgg aaggaagatg
   667081 aacagacgga ccttgaggac gccaagccga tggctgcgga gtgatcgcca tgaccgagaa
   667141 gaaccccaga accctgctct atctcgacgg cgtgtccgtc tccttcgatg ggttcaaagc
   667201 tctgaactcg ctttccttcg tcgtcgaacc cggggaatta cgcgcgatca tcggaccaaa
   667261 cggcgcaggc aaaacgacga tgatggacat catcaccggc aagacgaggc cggatgaagg
   667321 cgaggtcttc ttcaagggtg atatcgacct tacgaagagg gacgaagccg aaatcgccca
   667381 gctcggcatc ggccgcaagt tccagaagcc gactgtcttc gagaaccaca cggtctggga
   667441 caatctggaa cttgcgctca accgcggccg cggcgtcttc gcaacgctat tctaccggct
   667501 gacgggtgag gacaagaggc gcatcgaaga gattcttgcg acggtgcggc ttacagctcg
   667561 ccgggacgat ctcgccgccg gtctctctca cgggcagaag caatggctgg agatcggcat
   667621 gctgcttgcc caggaaccgg aactcctgct cgtcgatgag ccggtggcgg ggatgaccga
   667681 tgcggagacc gcggagaccg ccattctcct gaaagacatc gcaaagaccc gctcggtggt
   667741 cgtcgtcgag cacgatatgg gctttatccg cgatctgggc gtcaaggtga catgccttgc
   667801 ggaaggatcg gtgctggcgg agggctctat cgatttcgtc agcaacgatc cgaaggtaat
   667861 cgaaaattat ctcggccgat gagcgggagg aattgaagcg atgttgagcg tggaaaacgt
   667921 cgatttgcac tatggggccg cccaggcgct tcgaaacgtc accttcaagg cggaaatggg
   667981 caagatcacc tgtgtgctgg gtcgcaacgg cgtgggcaag tcgagcctgc tcagagctat
   668041 caccggccag catccggtca cgagcggcac gatctccttt aacggcacgc cgcttgatgg
   668101 cttggcaccc ttccggcgcg caaagcacgg cgtcggctac gtgccgcaag gccgggagat
   668161 cttccctctc ctgacggtga aggaaaatct gcagaccggc tacgcgccgc tgaagcgggc
   668221 tgaccgctcg atacccgatg acattttcag cctgttcccg gtattgcaga cgatgctcgg
   668281 ccggcgcggc ggcgaccttt ccggcggtca gcagcagcag ctcgcgatcg cgcgcgcgct
   668341 cgtgacccgg cccagaatac tggtgctcga cgagccgacc gagggcatcc agccatcgat
   668401 catcaaggac atcggccgag cgatcagata tttgcgggat tcgaccggaa tggcgatcct
   668461 gctcgtcgaa caatatctcg acttctgccg cgagcttgcg gatcatgtct atatcatgga
   668521 ccgaggagct ttcgtgcacg aaggggcgcc ggagacgctc gacacgcctc aagcgcgccg
   668581 gcatttaacc gtttgaactg gcataaggaa ttacatgctg ttttccacag gttttcgaga
   668641 taagcagttg tttcagatgc ttagtccgga tgttggattg caagctcgcg caccggccgc
   668701 agaaaaaatc cacctctttt gtggattgcg tttgctcgta caagcgcttt gacccatact
   668761 gcacatgcat gttcgatgat tgctcctgct tggttctttg aacggaagcg atatcaacga
   668821 ccaaccatgc agcagttcaa agtgtcgcgg cgcccttcat gcctctgtac gaggccggac
   668881 gccgctgaga gtatcgcact cgactttcac tgacagaatt ggccatttcg tgtttccggc
   668941 ctatccaatc ggaggagacc ctaatgacga atttcctgcc cgccctttac caagggcatg
   669001 cccccatcac gctccagact ctcttcaaag acgccctcga agcctatgac gattgggaag
   669061 agggcatgcc agaacccatc gtttccttcg aaggcaaagt cctcccggtc agtgccgttt
   669121 tccaatggat gaggccctgc acggacctta tgcccgccaa tatgatcgtc attgtcgccg
   669181 accggctgac aaagccgtgg agcggcgccg gaccaatgga tgcgatgacc ttctcgacgg
   669241 ccgcccgcgt catgtccgtc ctcgtgcggc ggcgcctgaa gcgattcggc cgcggttcca
   669301 tcgaggcctt cgcagagcgc ttcagtcagc cgatgcatgc ggcggcgcac gaaggctgaa
   669361 tcgacctgac aatggtacgc ccctctcctt ggactaaacc cgaggagggg ggcgcgtttt
   669421 ttttggcgat ttggagcaaa gtcgaaatgg ctagtttctc tgcttttcca cgaaggcggc
   669481 atgccatctg gcgagcatgg cgactgcttc ctggacaaag gccgggtggg tgccggggag
   669541 gaattcgatc cttggcgttt ttccatcgcg tctcagccgc gcgaagggct ggccggccgc
   669601 gtccaacagg tcctccggcc gttccggttc cggcttgtct ctctcggaca cgcaattgaa
   669661 aacgagctga aagcgctggt cggtttcggc agcgcggaag cggggcgagg cgatctcgtc
   669721 cttggcccga gcgcgcgcct cttcccttat gagcaggccg ccgatcgcca tccagcgctc
   669781 gcgcccgact ttcggcgccg gaccaatggc gcgggcgatt tcgtgcggca cgccctccgc
   669841 cacctgcagc agccgcgaca gttcgctctt ctgcaccgcg agagcatcgc cgatcacctt
   669901 gcggtcgaag ccgcgcaccg cgagagcggc ggcgaacagc gcacgctcga tgaaggaaag
   669961 gttgcgtcgt tcggcatttt ccttgccctg cgcgagcacg agttcgtcgt cggtcagcgg
   670021 ccggacgatc gccttgacct ggagctcgag ccggcgcacc gccttcaggc gccgatgccc
   670081 gtaggcggtc tgataatggc cttgcctttc cgggtgtggc cgcacgagga tcggcgattg
   670141 ctggccgttc tcgcgaatgc tctcgacgag cgcgaggaaa tccgggtcgt ccacttcgcc
   670201 gttggtcagc cggtcctcga tgaacgaggc cgcgacgaga gccggatcga gcgaaacgat
   670261 gcgttcaccc tggttcaacg cttccctgag aacccgcgct tcctcggcct cgcgggtgat
   670321 gctgccaagg gaaagcccca tggccttgac ggcgccggaa gcggcgcggg ccttggcggg
   670381 gtccggtaca tcgcgggcgg cggtcggtct ggcgttgaca ggtgtcaact ccccctgcat
   670441 cgcgtcggcg ggtgcttgct gattggcggc aggcgcgctt ccagaaaaga gagcgcgcaa
   670501 ttcgttcttc cggttgttgc cagccatgtc ctagcgcccc catgctgcat gaatgagagc
   670561 ctcgatctcg ccgttgaccg cattcagcga ctcgatcgcc cgatcatagg tggcgcgggt
   670621 gaaattctcc ctcccgacct cgtaaagcgt ctgcttggtg agaccggcgt ccgaaattgc
   670681 ggtcgacttt accatggccg aggtcaggac ccgctctccg aagagcgagc gcatgaagcc
   670741 gacgatctga gcctgtggtc cgtcattcgg ctcgaagcgg gtgaccaggt aacgcaggaa
   670801 gtcgaagttg agctcgccgc ccgcctcacg caccacgctg agcaggtccg aggtcatgta
   670861 gaggaactgg ttcatcgagg cgacgtcgag catctgcgga tgcacggtga cgatgaccga
   670921 agtcgaagcg cagagcgccg agagcgtcag gtagccaagt tgcggcgggc agtcgatcac
   670981 aaccacatcg taatcgtcgg cgacgcttgc aagtgccgcc tgcacgcggg cgaagaagag
   671041 cggtccggca tctgcgccgc tctggcgcgc gctcagggcc tgaggcgtcg tgtgctcgaa
   671101 ttcctgcagt tcgagattgc ccggtaccag gtcgagcccg tcgaaatatg tcttgcggat
   671161 gatttccttc aacggccggg cctcggcatc gtaacggatc gcgccataga gcgtatcgtt
   671221 gcccgtcagg tccagttccg gctgataacc gaacagcgcc gagagcgacg cctgaggatc
   671281 gaggtcgacc gcgagcaccc ggtgtccggt gagggcaaga tactgcgcga gatgaaccga
   671341 cgaggtcgtc ttgcccgagc cgcccttgaa attggtgacc gaaatgacct gcagatgctc
   671401 gcttcttaag gcatcgcgcc atttcaggta gccccgcgcc ttggcgccat tccccttgga
   671461 aaccgcctgt tcggcgaggt gccggcgcag tgcgttgatg tcgcagagcg agtaggagcg
   671521 gcgcccgccc gcaccggtgt cgggctgcgg cccttcgcca gccaaagaca gctggcgcaa
   671581 atacccatcg gaaacgccga tcagcttggc cgcctcgccg gaggtgaagc tccggagcgt
   671641 tttcctcgca gtgggcggaa agagccggtc gcgcatcgcc ttcagctgtt cggacagcgc
   671701 tcgcgcatcg gcggcaatcg cctcgtctgc cggcctgccg aacgccgcgc cgcccgcggc
   671761 agtcgtctgc gctgccgata ccttcatatt catcgtcgaa tctcctcgtg cgcgcatgac
   671821 gcgccgccgc cacgcagatg cgcccgccgc atttcctgac agaacaatcg gtaagatacg
   671881 ctgaaaagcg aaaaatgcgg tctattccgt tagaggaatg attcatcctc tgattcgggt
   671941 caaccgattt ttcggggctc tagtccgact gcttctcgcc gccattctca tcctgccggg
   672001 ggcgaggcga tcgcggctgc tttcgtcggc ctactgcatg tttccttgaa tcggatccga
   672061 ttgaaggaca aaaacgtgca gcagatcaaa gtgctacagc gacctttgtg cgtctgataa
   672121 gacgcacggc gctgtagacg gacgggcagc cctatgcgcc ttccacggga gggatcgggg
   672181 cagataacgg gctccccagg ttcgtcacga cgaccggcgt tccgttctgt acccggttgt
   672241 agagatcgac gacgtcctgg ttgatcatgc gcacgcagcc ggacgagacg gatttcccga
   672301 tggtccacca ttcgggtgaa ccgtgaattc gataaagcgt gtccacacca ttctggaaaa
   672361 tatagagcgc ccgggcaccc agcggattgg tgagacccgg ttccatgccg ccattggcga
   672421 tgctgtaggg ctccagttcc ggttgccggg cgaccatctc gtcgggcggc gtccagcgcg
   672481 gccactggcg cttgtactga atgacgccgc gccctgccca ttcaaagccc tggcgcccga
   672541 ggccgacgcc gtagcgcatc gcctgtccgg cttcgtaggt cagataaagg aagtggttcg
   672601 cagtatccac gaccagcacg cccggccgct cgccagtcgg attggcgacc atctggcgat
   672661 agaagcgcgg gtcgatcttt tcatacggta ttgcaggaag cggaaagagt tcatccggct
   672721 tcgggccgta gacgctcgca tagatggaat tgtcgacgag cggaggggcc ggctcggcgt
   672781 tcctggccga actggtggag cagccgccaa gcatggagac tgacgctccg aggctgccgg
   672841 caagaaacgc acgccgcgtc agaagttcat tcctcaaaag ctgtcctcgt tttcagtttg
   672901 acgatcccgc atatggatcc gcgagcgccg cttgcggcct gctgacggga tacttggttg
   672961 cagagattgc cgcggcgagc cggtcgggtc caactttttc cagcatcgtg cggaaggtcg
   673021 gatgcatgcc gccgtcgaca taggcgaaaa tcggagtggt tccggaagag gcaatagcgg
   673081 tctcaaccct gtggccttcg gcctcgatcc tggccaggag ctcggtatca gccgtagaca
   673141 tggcggaagg acatgccgcg agcgggtcgc gcggttcgcc gccctcaaat tcggtgttga
   673201 agacgtatcg acctccgcaa accgaaactt tcggctgtct tcggctgaac gcgaaggcgt
   673261 catagccttg cttcagcgtc ttccagaaag ccatgctcgg gtctcccttg tgaagggcca
   673321 tgttttccgt ggtcatcctg aatggatagg cctgcacctg gaagtgcttc tgtccggccg
   673381 cgagggccct ttgcacgatg gcgtagatct cgccgacgcc tcgatcggtc atggcataac
   673441 agccagcgga cgagcatgcc ccatgaacca tcagagcctc gcccgtatag ccgagcgccg
   673501 attcgagcct gttcggataa ccgagattga aggagacgta atactgcgaa ttgggattaa
   673561 gcatccgggc tgagacgtga tagaagcctt ccggcgcctg ccggtcaccg tcctttttct
   673621 tcggaccaag cttccccgac caacggcaca tcggataggt cttgaacaac gcataggtgc
   673681 cgctcgcgtc ggccttccac acctccagct cgctctcctt cttgaatatc cgcacgagca
   673741 cgggactgtt cggggacatt ttctttttcg ccatctcggc gagcactttc ttggacaact
   673801 gtggcggagc tttcgacaga tcgtagagcc ccatggcgag gcatccggaa agaaatgccg
   673861 cggccgacaa tgcgagccct attttagcca tgcgaacgat cgtgactgga gtgatacgca
   673921 tcttctgaaa cgagatcctc aataatgaga agccgcgcgg ctccgttctc tccccagaaa
   673981 acaccacgaa agctccgacc cgcacaagat cgtgcaattc actttcccgt tcgttaacca
   674041 tagcgatacg gtcgcggacc ttcttcgggt ccggtcgcca gcagccgcct tacgccgcgc
   674101 ccgctgccga aacttttccg gaacgaaaca gaatttgaac agctgcgaat tgcggcgccg
   674161 aactctgcaa agccttggat ccgctgggcg gcgaaggtat ttcgcagctc ccaggggcga
   674221 ctgtcgtgct cattcggcga ggctgcagga agtaagttgt taaccttcat ttcctattcc
   674281 ctagggcagc cccttcgatg atgaatttcg agttttcagg ccatgcgcat tccccggaca
   674341 aatttctcga ctgcagcttt gtatgacgcg aatcaggcag aggatttcga ggatccacag
   674401 ccggttgtgc cgggtatcgt gcatgcttcg gcgcccgaat cggccgctca cgaccatctg
   674461 ttcgaagcac cggaagcgcc gcggcgggcg tccggctacc ggcaggagga gatcagccag
   674521 gcgacgcgtg ccgtgcgcct ctacggtcat ggctccgcct atgccccggc cgaggtgacc
   674581 gtttcgacac gggatccgct tccgacgctt gcagaaatca ccggcctttc ctgcgaaccg
   674641 ggctgggaga gccatttctt tctgtcgccg aatgtgcgtt tcacccgcac gcccgagcgc
   674701 gagttcatga agcgccggcc gccggtacct gaagacaacg aggttgacgt cgccgaagca
   674761 gcggccgaag ccccacttgc cgagacggtg accgggaagg agccggtcga gccgctgccg
   674821 tccccggcgg aaacggacgc gccgtcgtac agcccgtccg aattgctccg cgtgctggtg
   674881 cagcagcttc cgtccttcaa cgccgcgcat ctgcaaacgc cggaaaaaaa tgccgtcgaa
   674941 caagcggccg aagctgccgt cctgacggaa gaagagccct ccattccgca ggcgccgcat
   675001 gtcccgatca tggaagaggc tccggtggtt gcggacgcat caacgggcac cgccgctgtg
   675061 cccgacagcg ccggagcgga agacgttgcg cgccaggcgg aggcgcgcct ctcctacctt
   675121 tccgattttg cgtttttcga gttcatgccg cttgaaccgc cggttgcttt gcgcactgtc
   675181 gcggcacctg ccgaggagtc cgcgcatgtc gcggcgccga gctcagccct gccaaaagcc
   675241 gctgcgccca acatcgtctc agcgcctgtc aggatcccgt cgcagccgcc ggcggcgatc
   675301 acttcgctgt tccgggtggt cgaatgccgg cggcccgagg ccggcccgga cgtgtccgcg
   675361 cccgacgcgc ctcaagatct cggcgctgag ccaatctctg ctggggctgc cgtcggcgca
   675421 gaagccgttg aagcacaggg tctgactccc gaagcccccg acgagcctgc acgggagccg
   675481 gcgcccgaag ctgccgtcgt gcccgcaaag gaaccggcgc ccgaagcgcc ggtgaccagg
   675541 gcggcaatca ccatgccggc ggtgatccag cgttcgtcgc cggctctgcc gccggtcggc
   675601 gcgaccgaac ggccgggtat cgctgacgcc tacgagtttc cgtcgaagga actcctgcag
   675661 gaaccgccgc aaggccaagg cttcttcatg acgcaggaac agcttgagca gaatgccggc
   675721 ctgctcgaaa gcgttctcga agatttcggc gtcaaaggcg agatcatcca tgtccgtcca
   675781 ggcccggtcg tcacgcttta cgagttcgag cccgcgccgg gcgtcaagtc ctcccgcgtc
   675841 atcgggctcg ccgatgacat agcccggtcg atgtcggcgc tgtccgcccg cgtcgcggtc
   675901 gtgcccggcc gcaacgtcat cggcatcgag cttccgaatg cgacgcgcga aaccgtctat
   675961 ttccgcgagc tgatcgagtc cggcgatttc cagaagaccg gttgcaagct ggcgctttgc
   676021 ctcggcaaga cgatcggcgg agaaccggtg atcgccgaac tcgcaaagat gccgcatctg
   676081 ctcgtcgccg gcaccaccgg ctcgggcaag tcggttgcga tcaacaccat gatcctctcg
   676141 ctcctctacc ggctgaagcc ggaggaatgc cggctgatca tggtcgatcc gaagatgctc
   676201 gaactctccg tctacgacgg catcccgcac ctgctgacgc ccgttgtcac cgatccgaaa
   676261 aaggcggtaa tggcgctcaa atgggcagtg cgcgagatgg aggaccggta ccgcaagatg
   676321 tcgcggctcg gcgttcgcaa catcgacggc tacaatcagc gtgctgcggc tgcgcgagag
   676381 aaaggcgagc cgatcctcgc gaccgtccag accggcttcg agaagggcac cggcgagccg
   676441 ctcttcgagc agcaggaaat ggatctttcg ccgatgccct atatcgtcgt catcgtagat
   676501 gagatggccg acctgatgat ggtcgcgggc aaggagatcg aaggggcgat ccagcggctg
   676561 gcgcagatgg cgcgtgctgc gggcatccat ctgatcatgg cgacgcagcg tccgtcggtc
   676621 gacgttatca ccggtacgat caaggctaat ttcccgaccc gcatatcctt ccaggtgacc
   676681 tccaagatcg acagccgcac catcctcggc gagcaggggg ccgaacagct actcggccag
   676741 ggcgacatgc tgcacatggc cggcggcggc cgcatcgccc gtgttcatgg cccctttgtc
   676801 tcggatcagg aggtcgagca cgtcgtcgcg catctgaaga cgcagggacg cccggaatat
   676861 ctcgaaacgg tgacggcgga cgaagaggaa gaggagccgg aagaggatca gggcgcagtg
   676921 ttcgacaaga gcgcgatcgc cgccgaagac ggaaacgagc tctacgatca ggcggtgaaa
   676981 gtcgtgctgc gggacaagaa gtgctcgacc tcctatatcc aacgccgcct cggcatcggc
   677041 tacaatcgcg ccgcctcgct ggtcgaacgg atggagaagg acggtcttgt cggtccggcg
   677101 aaccatgtcg gtaagcgtga gatcatctac ggcaaccgcg acggcggtcc gaagccggac
   677161 agcgatgagt tggactgagg catcgagcat atccaggaaa aatgcgcagc ggttttccgc
   677221 ccggattgca gggactgctc caggtcgctt cagctccctc cccccaccgg gcgggagctg
   677281 cggatcacgg ccggacggtg acgcggccct tcatgttggg atggtagcgg caggtataat
   677341 cgaagctgcc agcttccttc agcaccagcc ggccggattt tttggccggc agaagcactt
   677401 ccgcgccgcc tttgacggtc gccgtgtgca cgagcacatc cttgttgatc cactcgatct
   677461 cgtcgcccac cctcgcatcg acctccgccg gcgagtagac gaggcgatcg atcgccacga
   677521 gaatggtttc cgcctgcgaa ggagcggcaa tgccggccgc tcccaccgac agcaagacaa
   677581 ttgccgctcg cgatgcaaac attgccgcgc tcacttcaat tcggccgcga catgttcggc
   677641 atgctgctga tgcccccgaa acagcttaag gccggtctcg agcagcgatt tgagttcggc
   677701 gttctgagct gacggaatca gcagcgtttc cagcgcgccg ttgacctgct tgtgataagc
   677761 gacctcttgc tcgatatagg ccttgtcaaa cgccgcaccc tccagctttg ccagttcctg
   677821 acgcttcgac tcggccgcct gcgagagcga cttgctggtg tcgttgtctt ccggcgtgac
   677881 gttgagtttc ttgacgaggt cgagggcttg cgtgttcacc gtttcgtggt cgcgcagcat
   677941 gctctcggcg aattcgacga cggtcttgtt cttagatgtt gcgatcgcct gttttgccgc
   678001 ttcgatgtcg aggaggcctg cggtgtaggc gatatgggca atttgcggat ccgtcggctt
   678061 atcgttgccg agcgcaccgc tggcgccgat aagcagggcg attgcggtcg ctgcggtcgt
   678121 cagtcggatg gtcatttgat gttcctttcc tcgaagatca aagcctttgt tgaatgacgt
   678181 gcttttgatg cttcgcggcc cgaaacgttc ccgctatttc attgggattt cagcgaggcg
   678241 ggcgagaacg gcctcggtca accgctcgca gcgcattccc gcgaagggga aggcatcgag
   678301 cagaaccggg ccgatctgcc gttccagttg ctccttgagc agccggcgcg cccggtgcag
   678361 ccttgtgcgt gccgtttccg gcttgagacc gagaagggcg gtcgtctctt cattgcttaa
   678421 cccctcgatg acgcgtagca cgaataccgt ccggtaggcg tccgggagat cgtccgtcag
   678481 cctttcgacg agatcgagaa tttgccgctg tgccatcgtc ttttccggat cgctgatgcc
   678541 tgaattgagg ggaaaggcga taatctccgc ctcttgcgac tgccgcatgt cgctggccag
   678601 tttcatctgg cgccgtcttt tccggaggcg gccgagcgcc tcgttgatga cgatccgggc
   678661 aagccaggtc gtgatcgcag cgtcaccgcg aaaatcttgg aaacgcgtaa aggcacggac
   678721 ataggcctcc tgcagcacgt cttccgcatc gctgtcgttg cgtaggatgc tccgggcgat
   678781 gcgataaagc ttgcggttat gggcctgcat gatcgcccgt aatcgggcga gatcctgcgc
   678841 gggtggcgac gcattcaggc aaaggtcgat ttcagtgaca ggcatggtcg ggctccttgt
   678901 gacgcattgg atgccctgtc tctggagatg ttcccggcaa aatgctgccg gatatcttcg
   678961 gatcttacca gtgaatgagg acggtggctt cttcttgagg gggaggagcg acccttggcg
   679021 ccggcacgac gcgtcgcttg aaagagaaag cccggcgcgg gaggaggtgc gccgggcttc
   679081 cgatcctgac cggcaacggg gaggaggagg gttgccgatc ccgcgatgga actgggagga
   679141 ggagtgttcc atcgacaatc agataataat gctgcggtgc agcatcttca aggccgggaa
   679201 tggatttttt ttttcgtccg ataaaaacac gatgtgcggc atcggcgtca tgcgtaaggt
   679261 gcttgtcttt cccgccatat gcgccagact cgaagccgaa aggagggcaa cgccatgacg
   679321 aaggaccgca gggccgcttt ggtcaggatt accggacggg tacagggcgt gtgctttcgc
   679381 gactggacac gcgaggaggc cgagaagctt ggtctcgacg gctgggttcg caacgagagc
   679441 gatggttcgg taaccgcgct gatcgcaggg ccggatggtg ccgtcagcag aatgctggaa
   679501 aatttctgga aagggccgcc gggagcttca attgccgatg tcgcgagcga ggtggcttct
   679561 tccgtcgagg cgccggcggg atttcgcatt acacgataac tacacccgct agggccacgc
   679621 gatgccccgg cagacgccga tgcacatggt ggagagcgag tgcgcccacc cgtttcggta
   679681 agctccagcg ctgccgttcc agggatgcgt gcaccggaca tgccgactgc tggtcacaaa
   679741 cccggccgcg ccgggtctgt cgtgcggggg cgctgcgcgt ccttcttgcg tccgctcaat
   679801 agccccgcgc ggcgcctgca ccgatgcggc tgtcgagggc gccgttgtag cgggcgccgc
   679861 cgcccgcctc gatctcggcg atgttctcgc cgccgacgag gatgccggcc gcctgtcccc
   679921 agatcgtcca gttttcgtcg atctcgacgt cgtggcccat ggaggagagc agcttacgtg
   679981 tgtcgggcga aagcgcatag ggctccataa agaccttgtc cgggagccat tggtgatgga
   680041 tgcgcggcgc gtcgacagcc tcctgaatgg tcatgccatg gtcgatcacg ttgaggatgg
   680101 cttcaagcgt gatggtaatg atgcgggcgc ccccggggct gccgatcacc atgaggggct
   680161 ttccgtcttt ggagatgatc gtcgggctca tcgatgaaag cggcgtcttg ccgggctcga
   680221 ttgcatttgc ctcgccctgc actagcccat agaggttggg cgcaccgggc ttggcggtga
   680281 agtcgtccat ctcgttgttg agcagaatac ccgtgccggg cgcgacgacg cccgcaccga
   680341 aggaaccgtt cagcgtgtag gtgacggcga cggcattccc ctcgtcgtcg acgatagagt
   680401 aatgagtcgt ttccttgctt tcggtaaagc ccgccggcat cagcgcttcg gagacgccgg
   680461 ccttgaaagg atcgatcttg gcgcggatct cttttgcata tgccttgtcg acgagctttg
   680521 cgaccgggtt ctccacgaag gccgggtcgc cgagcgccgt gttgcggtcg acataggcgt
   680581 ggcgcatggc ttcgatcatc gcatgcactg tctcggccga gccgtagccg agataggaga
   680641 gcggatatcc ttcgagaatg ttgaggattt cgcagatgat cacgccgccc gacgatggcg
   680701 gcggagagga gacgatctca tagccgcggt aattgcacct gaccggttcg agttcgcgga
   680761 cctgatagcg ctcgaaatcc tgctttgcga gaatgccgcc cttgtccgtg ctcgccttga
   680821 cgatggcatc tgcgatcgga cccctataga aggcgtccgt gcctttctcc gcaatgctgg
   680881 caagcgacgc cgcaaggtcc gtctgaacca gccggtcgcc gactgcgaag ggctttccat
   680941 cgggcttcag gaagatcgct gcggcggccg gatcacgggc caggcgctcg ttctcgccat
   681001 cgaaggagtc aatgtcgccc tgctcgagca cgaacccttc gcgcgcgagc ttgatggccg
   681061 gttctatcaa ttcgttcaac ggccgcgtgc cgtaacggtt gcgggcaagc tcgaagccca
   681121 tgacgggccc gggcacaccg accgccagat agccttcggt gctcagtcct tcgacgaggt
   681181 tcccctggtc gtccagatac atggtcttcg tagccccgat gggcgcgcgt tcgcgaaagt
   681241 cgaggaaggt cgtcttgccg tccttgaagc ggatggtcat gaagccgccg ccgccaatgt
   681301 ttccggccgt cgggtagacg accgccagcg cataaccgac cgcgaccgcg gcatcgatcg
   681361 cgttgccgcc tttcctgagc acctcgacgc cgatatcgga agcaagatgc tgggccgtaa
   681421 cgaccatacc gtggtcggcc ttgaccggct caggcgaggc cgcctggccc tgtggcacga
   681481 atgcgcaaag cgcgagcatg agaataatgg acacggattt caggcggggc ccggatttca
   681541 ggcaggaatt gggcatgcga tcctcccgga caggaatgtt gataaagatc ggcgcactta
   681601 tgcgtaccac cctcacacgg gggactgtag catcaaaaat tatgggttgc agtcgaaagc
   681661 gggcgctcaa tcgccggaat agcgctcctc gagccacggg tcgccgcgca tgtggtagcc
   681721 gtttcgctcc cagaagccgg caaaatcggc agcgcggaaa tcgatgcgct gaagccattt
   681781 ggcgcttttc cagaaataga gatgcggaac gaccaggcgc atcggcccgc catgggcgcg
   681841 gctgattggc tcgccttccc aggcggtcgc gaggatcgcg tcctcggcgg caaaatcggc
   681901 gagcggcaga ttggtggagt agccgtcata gctcgtcagc atgacataga ccgcctccgg
   681961 cttaggcatg gcacggtcga gtaggtcgcg cgtgtgaaca ccgcgccacc gattgtcata
   682021 gcgcgaccag gtcgtcacgc aatggatgtc cgattggctg tcggtctgag gtagcgcctg
   682081 gaaggcggtc cagtcaagcg agagcgggtt ctcgaccagg ccggtgatgt cgagccgcca
   682141 ggtctcatgc gtcaggtgcg gctgctgccc gagatccagg attggccagt cttttacgag
   682201 atgctgaccg ggtggcaggc gatcggtctc cggacgggcg gtgcggcccg tgaggaattt
   682261 gccgtcggcc gcccagcgac gctttgtgga agtgagcttg gtctccggcg cctctgttgc
   682321 ttcggccacg actgttctcc atccatgggc gtgaatacga attagacgtc tcctgaatat
   682381 ccaggtcaac gatgttttta ggtcggatcg acctggcgcc gtcaaagtca ggcaccaagt
   682441 ctttcccgtt cggctgtccg ccaggcgcgc ggcgtcatac cagtgcggcg caggaagaag
   682501 cgtgagaaat aagccgggtc gccaaagccg aggcgaaatc cgatctgctg cacgctgccc
   682561 cgggtgaaca ggagctggcg ctttgcttct tcgacgagtt tgccggcaat cacctcgtgc
   682621 aggctccggc cggtggctgc gcggacgatg cggctgaaat gggtcgggga gagcccgagt
   682681 gcgcgcgcat agaaagcagc cggacggtgc gtgagatagt gttggcgcag gagcgcgtcg
   682741 aaacgctcca tccggcgttc attctcgctt tccgcgcctt cgtcatcgcc gccttcggcc
   682801 aaccgccccg taaggacaag ggcggtcgtc aggtaggcgt cgagcaggac ggtgcggtgg
   682861 ctgagccccg cctcacactc ggttgcgagg cggcgcagcg tctcgccgat atagcggccg
   682921 tcttcgctgc cgccgagcgg cgtcaagcgc ggcgctgcca tccaggcgcc cggccggctg
   682981 cttcggcccg gcgaaatcgg cagatgcgat gcgagcacag tgaagacgaa gccgtcgaca
   683041 tcaggcgaaa accggaagcc atggccaatg ccgggcggga cggtgatgac agccggcgac
   683101 gagatctgct cgaccgtctt ctcgaaaagg gcatcgccgg agccgccggc aatgtacaat
   683161 atttgaaaga agcgctcgtg ccggtgaaga ccgatctccc agcggtagag gctgctgcgg
   683221 gcgtgaatgg tctcgcaatg cagccagaaa tccggacgct cgcgggattt ctcgccatag
   683281 agttcataat taggaacggg tgccttcatc tgtcctgctt tcggcggatg ttcgataagt
   683341 gcaatttcct ggtggaaatg tccattgaga cgggggctgc cggcgcgcag aatttccagc
   683401 gtaaccggga gggtaatcat gcgcactcag gtcgtcataa tcggctccgg accttccggg
   683461 ctcctactcg gacaactgct tgcgagggcg gggatagcaa atgtgatcgt cgatcatgcg
   683521 agcaaggatc atatcctcgg ccgtgtgcgc gccggcgttc tggaggaagg gacggtccgg
   683581 ctgatggacg aggcgggctc aggcgcccgc atgcatgccg aaggcattgc gcatgacggc
   683641 ttctcgcttg ccttcgacgg gcgcgatcat cgaatcgacc tcttcgggct cacgggcggc
   683701 agacgggtga tgatctacgg tcagatggaa ctcacccgcg acctgatgga tcagcgggaa
   683761 agggccggcg ccccctcggt ctacgaggcg gaaagtgtca ccccccgcga tttcgaaggg
   683821 gatgcgcccc atgtcgccta ccgtaagaac gggattgcgc accgcatcga ctgcgacttc
   683881 atcgccggct gcgacgggtt tcatggcgtc agccgccgtt cggtgccgca aaatgccttt
   683941 cgcagcttcg aaaaggtcta cccattcggc tggctcggta tccttgccga cgtaccgccg
   684001 gtcgacgatg aactggtcta tgccaatcat ccccgcggct tcgcgctctg ttcgatgcga
   684061 tctcatacgc gcagccgcca ctatattcag tgcccgctcg gcgagaagat cggcgactgg
   684121 agcgatcaac gcttctggga cgaactgcgc cgccgcttgc cggcccatca tgccgaacgg
   684181 gtggtgacgg gaccttcctt cgaaaaatcg atcgccccgc tgcgttcctt cgtcgccgag
   684241 ccgatgcgct tcaaccggct gtttttggcg ggtgatgccg cgcatatcgt tccgcccacc
   684301 ggcgccaagg gcttaaacct ggcggcaagc gacgtgcact atctcttcga ggcatttgtc
   684361 gagcactatc aggaccgctc gaacgccggc atcgacgcct attcggcccg cgctctcgcc
   684421 cgcgtctgga aggccgtacg cttctcctgg tggatgacga cgatactgca ccgcttcccg
   684481 gagacgagcg agttcgacca gaagatccag gaggccgaac tcgcctatct cacccactcg
   684541 agcgcggccg cgaccgcgct cgcggagaac tatgtcggcc tgcctttctg agaccccgct
   684601 ctcaaaccct cgagcgaggc tacttgcgcg ccgatacggc ctctgctcga ctgcgttgcg
   684661 ttcgaagaga ggaagacttc acaggggagg agtgcgatgg ggcttacgct gcgccagatc
   684721 gaggtcatcc gggcggtgat gatcgccggc acgattgcag gtgccgcgcg cctgatgaat
   684781 gtcgcgcagc cgggcgtcag ccgcaccatg aagcacatcg aaagcgcgct cggcatcaag
   684841 ctcttcgtca ggaaggcggg acgttacgta cccaccgccg aagcgcgcaa cgtcttcgcc
   684901 cagctccagg aagtccaccg aaaggtggac gacctgcaat tctcgatcgg tcagctcgag
   684961 cgcgggcggg gcgtggagct ggcgctcggc tcggtgccca gcatcgccaa cgccatggtg
   685021 ccgcaggcca tcgccacgct catgcggcgt catcctgaca tccgcatcaa tttcgatatc
   685081 ctgagaatag aggaggcgat cgattatctg ctactcggca agggagagtt ggtcgcgatg
   685141 agctaccatc tctcccatcc ctcgatcacc ttcgaacccc tgtccagggg gcatctcgtc
   685201 tgcatcgccg ccagggagca tccgattgcc gaaaggacca gcatttccgc gcgcgagatc
   685261 gccgggcacc cgcttatcgg cctcgacccg cgcgatccct acggagcaat catcgccggc
   685321 atattcgaga gcgaggggct tgaatatcac acgcctatca gggcccgctt cggcacgacg
   685381 gtttgcgcgc tggtcaggcg gaacctcggc atcgctgtcg tggatgcatt caccgtcggc
   685441 gatatgaccg accaggggct tgccgtcatt ccaatcgacg aggagaccgg cttccagacc
   685501 tatgtcgcct accgcgccga tgccgtgctt tcaagctatg ccgagaggtt cgtgaagaca
   685561 ctacgccggg tcatgaacga atcggttagg cgttcgaccc ggctgacgga actataacta
   685621 aaagatatgg gcgactgaaa aaacggtatt tgcgttatga gcgcaaactg aggatcattg
   685681 gtccgtcggc ccttcccgcc ttttgatcgg catcttggtg aagaacggcg cgagcgagag
   685741 gacatgggca tgaaaacctc gattgcgact gtttcgatca gcggcactct ttcggagaaa
   685801 ctcgccgccg tcgcggcggc aggcttcgac ggggtggaga tattcgaaaa cgatttcctg
   685861 accttcgacg gctcgcctgc ggaggtcggc cgcattgtgc gcgatcatgg attgaaggtg
   685921 acgctttttc agccttttcg cgatttcgaa ggcctgccgg aaccgcaccg gtcacgcgct
   685981 ttcgaccggg cggagcgcaa gttcgacgtg atgcaggagc tcgggacgga attgatgctg
   686041 gtctgctcca gcgtctcgcc actcgccttg ggcggtatcg accgcgccgc cgacgatttc
   686101 agggagctgg gcgaaagggc ggcgcggcgg aacctgcgcg tcggctacga ggcgcttgcc
   686161 tggggccgcc atgtcaacga ccaccgggac gcctgggaaa tcgtccgcag ggccgaccac
   686221 ccgaacgtcg ggttgatcct cgacagcttt catacgctcg cgcgcaacat cgacctgcgg
   686281 tcgatccgct ccattccggg ggaccgcatc ttcatcgttc aactcgctga cgcgccgcgg
   686341 atcgagatgg acctcctcta tctcagccgc cacttccgca atatgcctgg ggaaggcgac
   686401 cttccgctcg tcgatttcat gtccgccgtc gccgcgaccg gctatgacgg cgcgatatcg
   686461 ctcgagatct tcaacgatca gttccgtggc ggatcgcccc aagcgatcgc cgaggatgga
   686521 catcgttcgc tggtttacct gatggatcgg gtgcggcgac acgagccggc ggcgaagagc
   686581 gccgaagcac tgcccgaccg ggtggaggtg ctgggggtcg agttcgtgga gttcaccgcc
   686641 gatcagacgg aggcggaagc gctcggctcg ctgcttgggg ccatgggttt tcgcgccgtc
   686701 gcctcgcatc gcgagaaagc ggtgaccctt tggcgacagg gttgcgatca ccgaggcata
   686761 aacgtcgtca tcaataccga gcagaagggg ttcgctcatt cgagctatct ggtgcacggc
   686821 gcatcggcct atgcgattgg cctgaaagta cccgatgcct cggccgcggt cgaacgcgcg
   686881 cgcgccctcg gcgccgaaat attcctgccg gagtcaggtg aaggcgaggg ggcgatggca
   686941 gcgatccgcg gtatgggcgg cggccttatt tatttcgtgg acgagatcga cgacgtctgg
   687001 tcgcgcgagt tcgtcgcgcc gggagatgat cggcagcctg cagcgaccct cgtcgccata
   687061 gaccatgtgg cgcaatccat gaaggaagag cagcttccga gctggctgct tttctataca
   687121 tccattcttg atgcggacaa gctggcacag gtcgatatcg tcgatcccgc cgggctggtc
   687181 cgcagccagg tcgtggagaa tgcgagcggg acgctccggt tgacgttgaa cggcgcggac
   687241 aatcaccgca cgctcgccgg ccacttcatc gcagagagct tcggctcggg cgtccagcat
   687301 gtggccttcc gcaccgacga catcttcgaa gctgccgaac acatgcgccg cagcggcttt
   687361 cgcgccttgg cgatctcgcg caactactat gatgacatcg aagtgcggtt cgcgctcgaa
   687421 ccgggttttg tcgacaggct aagagacgaa aacatcctct atgatcgcga tgaggatggc
   687481 gagtatttcc agatctatgg ccccaccttt ggagagggct tcttcttcga gatcgtcgag
   687541 cgccgctccg gttaccgtgg ctatggtgca gccaacgcac ctttccgtat cgccgcgcag
   687601 aaacgttgcc ttcggccggc gggtatgcct gcagaatagc tcctccgcgg agatgctttc
   687661 agcgctacaa cgccttcttc gtatctgcag ccattgccgc ttccgccgct tcgcgcagcg
   687721 tctgcatcag gatcgagagc ggcagcgacg ggatcgaatc ggtgcgcatg gtcaggccaa
   687781 caggtcctct cgtctcgctc gtatcgaccg gcagcgccga cagcatgccg tcggcgatat
   687841 ctgcagcgac cacgccggcc gatatgatcc agatggcatc gcttgagcgc acgaaggccc
   687901 gtccgaagga gtcggagacg gtctcgatct ggttcggcag gccggcgatg ccgttggcga
   687961 tcaggaattg ctcgacgaaa ggacggatga tcgaggcgcg ggttggcatc agcaccggat
   688021 aatcgctgag atgtgcgaag accgcccgct tgccggagag aagcggatga ccggcccgca
   688081 ccgcgaagac cacctgttcc gaatagaggt gctcgaagga aaatccggtc atcttgtcgg
   688141 gtgcggcaag cctgcccacg accagatcga ggtctcccac gcgcaattgc tcgagaagga
   688201 ctgcgttttc tccggtgacg atcttgatgc gtgcgccggt cttttccttc aggaatagcg
   688261 tgatggcgcc gggcatgatg cgggtggaga ccgtcggaag tgcgccgatg cggatcggcg
   688321 gaccgccgcc ggacagctcc tgtgagacgg aatcgaggcc ttgccgcagc gccgtcagcg
   688381 cagcgcccgc gtggcgcagg aagacctcgc cgtaacgggt gatcttgatg ccgcgcccct
   688441 cgcgctcgaa aaccgctacg cccagaacct cttcaagctc gcggatcgtc ttcgtgaccg
   688501 ccggctgcgt cacatgcagg agttcggctg ccttcacgac gctcttctgg cgcgcgacct
   688561 cgacaaatgt cagcagatgg cgaaacttaa cgcgagcgtc tatcacgttt cgcataactc
   688621 cctggttaag ttaaagccac gaaatatcat tttacctaac cagatgaaac atccagtttt
   688681 ggcgaaggag gagatctgac gtgcaattca cccgcatcaa cgacgtcacg atacattatc
   688741 gcgtggtcgg tgccgtcgca gaaaagcccg tgctcgtctt catcaattcg ctcggcacgg
   688801 atttccgcat ctggcgcgat ctggtcctcc gtctttccgg ggattttgcc atcgtgctct
   688861 acgacaagcg tggtcatggg ctgtccgata tcggtcaggt tccctactcg atcgaggatc
   688921 acgcgaccga tcttgccggt ctcctcgatc ggctggccgt caagggagca attgtctgcg
   688981 gcctttcggt cggagggctc gtagcgcaat cgctctgtgt ccgccgcccc gaccttgtgc
   689041 atgccctcgt gctttccgat accgcccata agatcggcac caccgagttc tgggacgccc
   689101 gcatcgctgc gatcgaggcc catggcatcg aggcgatcgc cgatggcatc ctcgaacgtt
   689161 ggttcaccgc agcctttcgg cgccccgaaa acactgcctt cgcgggctat cgcaacatgc
   689221 tggtccgcca gccagtgccc ggctacatcg gcacctgcgc cgccatccgg gatgccgatt
   689281 tcacgcaagc cgccgggaag atcgccgttc ccgtgctctg cgtcgtgggc gaagaggacg
   689341 gttccacgcc gcccgatctg gtgcgctcga cggctcagct cattcccggc gcgagcttcg
   689401 aagtgatctg cggggccggg catatccctt gcgtcgaaca accggaggct ctgacctcgg
   689461 tcctgaggcg cttcttccga accgtcttgc ctggagaaaa cccatgagcg atgcctttgc
   689521 ccattccgca cgttaccggc aggggatagc gacgcgccgc gccgttttag gcgaggatca
   689581 cgtcgagcgg gcacaacaga cttcgaccga tttcgaccgc ccgttccagg atttgattac
   689641 cgaggcagct tgggggcatg tctggtcgcg tccgggatgg acaaagcggg agcggtcgat
   689701 tgtcaccatc gcgctgctcg ccgccctggg acaggatgag gaggtggcca tgcatgttcg
   689761 cgcgaccgcc aataccgggg cgacgcggga agatatttgc gagacgctcc tgcatgtcgc
   689821 catctatgcg ggggttccag ccgccaatca tgcaatcaag atcgtcaagc aggtgttcgg
   689881 cgaaatggat gccagcacgg cttctcgata ggggtaggga gtgcgacgat gtccggagat
   689941 cagagcggcg gagagaacga caggcccgaa acgggcgcct tttttgcccg ggaccgcgca
   690001 tggcatccgc cggctttcgc gcccggatac aagagctcgg tgctgcgctc accgcaaaag
   690061 gcgctgcttt cgctcgatgg caccctgtcg gagatcaccg gcccggtctt cggccattcc
   690121 atgctcggcg aacttgacaa tgacctgatc cataatttcg ccaagcctgg cgaaagcgcg
   690181 atcggcgaac gcatcatcgt ccatgggcgg gtgctcgacg agcgcggccg cccggtccag
   690241 gacgcgctcg tcgagttctg gcaggcgaat gccggcggcc gctaccgtca caggaaggaa
   690301 agctatctcg cggcgctcga cccgaatttc ggcggctgcg gcagggcgat caccaatggg
   690361 gatggccact attgcttccg cacggtgaag cccggcgcct atccctggcc gaacggcgtc
   690421 aacgattggc ggcccgccca tattcacttt tcgatcttcg gccacggttt cgcccagcgt
   690481 ctcatcacgc agatgtattt cgagggcgat ccgatgatct ggaagtgtcc tatcgtaggc
   690541 gccattcccg accgcagggc gatcgagcaa ctgatcgccg cactcgattg gggtaatacg
   690601 gtgccgatgg atgcccgtgc ctacaagttc gatatcgtcc tgcgcggccg tcgctcgacc
   690661 ttcttcgaga atagacccga ggggaattaa ggggaaagcg atggctcagg atctcggcta
   690721 tcttaaggaa accgcgtcac agactgccgg gccctatgtt catatcggcc tgacgcccaa
   690781 tttctgcggg attggcgggg tctacgaagc cgacctcggc gcttctatgg tcaacgaccg
   690841 gacactcgga caacgcatta ccgtgaccgg ccgcgtgatc gatggggccg gtatgccgct
   690901 caaggacgca ctcctggaaa tctggcaggc ggatgccgcc gggctctata attccccgtc
   690961 cgagaggcgc ggcgcggcgg atccgaattt cgccggctgg ggacgctcgc cgacgggcgc
   691021 cgacgatggc atgttcacct ttgagacggt gaagccgggc cgtgttccct tccacgacgg
   691081 ccggctgatg gcgccgcata tcagtttctg gatcgtcgcg cgcggcatca atatcggcct
   691141 tcacacccgc atgtatttcc ccgacgaggc ggtggcgaac gccgctgacc cgctccttgc
   691201 ccgcatcgag caccgccacc gggccgagac gcttgtcgcg gcgggtcgga cgcctaatta
   691261 tgttttcgac attcatctcc agggcgagaa ggaaaccgtc ttcctggata tatgatcgtt
   691321 cggcagcccg gtccctccgc gctgccgcac gcgtgtgagg cttccttcaa atcgaagggc
   691381 gcgagagctg gagatgcggc atgacctatt cggccttcga tcacccctat ctttccggcc
   691441 tcctcggcga agaggcggtg gcagcggaat tctccgttgc cgccgacgtt cgcgccatgc
   691501 tcgccttcga ggcggcgctt gcccgcgcgg aggcgcgtca tggcatcata cccgaagccg
   691561 ccgccaaccg gatcaacgag gcctgccgcg ccttctctcc ggatgtcggc gcaatgcgcc
   691621 gggcaactgc cgtggacggc gtggtcgtgc ccgaactcgt gcggcaattg cgccgggcag
   691681 tcggcgagga agcggcggaa catgtccatc tcggcgccac cagccaggac gtcatcgata
   691741 ccagcctcat gttgaggctg aaggcgctcg ccgaactttt ctccggccgc ctgggctcgg
   691801 tgttgacagc cctggaggcg tgcgagcgcg aatggggcga acgcccgctg accgcacata
   691861 cgcggatgca gccggcgctg acgataaccg tcgccgatcg cctgcggagc tggatcgagc
   691921 cgctgctcga ccatcaggac aggctcgacg cggcggacct cgaccttttc gcggtacagt
   691981 tcgggggagc caccggaaat ctggagaagc tcaagggcaa ggccgacatc gtccgtgcga
   692041 cgcttgcgga ggaactcgcg ctcgtcgact gtccgcaatg gcacagccag cgctcgccta
   692101 tcgccgatat cgcccatctc ctgtcgctcg tcaccggcag cctcggcaag ttcggccagg
   692161 acgtggcgct gatggcgcag gcgggcgacg aaatcgtgct tgccggcggc ggcgcatcct
   692221 cggccatgtc gcacaagcaa aacccggtcg ccgcggaggt gctggtgaca ctcgctcgct
   692281 tcaatgcgac gcaggtttcc gccatccacc agtcgctggt gcacgagcag gaacgctcgg
   692341 gttccgcctg gacgctcgaa tggctcatcc tgccgcagat ggtcggtgca acagcggcgg
   692401 cattgaggct agccgccgaa ctcgccggga acatcaggcg attggggcgg gtatgacgta
   692461 agtggtagga ttgcgagccc gatgagctgc ctttcccctt ttcctcgggt ttaaccgagg
   692521 agagggggaa atccatcacg cgtcgaccaa caaggcggcg ggaaagtcgc ggaagatgcc
   692581 ggccacgtcc agaagagccc gaggctcgac aacaccgccg gtcaagagat tgcgcatggg
   692641 cttgagctcg cagccctccg gccagacgag aaacgtgttc tgccaaagtt ccggatcgac
   692701 cgataaccgg ttgccctcca accggccgaa gacaagccgc gggacgaccg tgagcgcaag
   692761 cttgtccttg ttgcggcgga tgaaggcggc agcgtgccgg gcccccggac cctcgatcgg
   692821 caccggcaaa tacgtagctt ccgcaagaca atcccgcccg cggccccggc gataggtcag
   692881 gcctatcgag atcagcgcct gcttgcaatt ctcgaaatcg gcgatcatcg gcgagcgcag
   692941 tagctgggga agcgaggcat gcggtgaaaa gccgcggcgg ttgtcgggat cgacgaggga
   693001 gaggtcggcg cgttcgctgc cctgatagat atccggaatg ccgggcgcgg tgagctttac
   693061 cagcgtttgc gtgaggctgt tgatcaggcc ggcctggatg aatggtccgg ccgtgttcgc
   693121 gaaatcgccg aggaaagatc ggttccccca atccaggaga tcgccgagaa atgccttgat
   693181 cgctgcttcg taccgctcgt tcggatcttc ccagctcgtc ctgagctttg cctcccgcag
   693241 cgccttcacg gtgaaggcga tcatccgctc gcgcagggaa atcaggtcgc cttcatcaac
   693301 aaggggctcg atcggccagg cgccgagcag gctctgatag agaaattgct cgaccgagtc
   693361 ctctagctcg tcgccgtccg gcagttggaa aatgctagcg gcattcatcc cgtgccagcg
   693421 ctccatcgct gctgtccaga cgtcggatgc ctcgctgatg acgtagagcc gcgcgcgggc
   693481 gtcctcgccc cgtttggtgt cgtgcgtgga cgtcgccgac aggccgtacg gcatctggct
   693541 tgcgcgatcc tgcatcatcg catggaagcg gccgacgccg ccgggcgacc agaaggggga
   693601 ggcacccacc tcgttcgcgg caagataatc gccgcgccga tagaagaaag tgtcttcgac
   693661 cgctttggcc atgaccgcgc cgctcaactg ctgaaaccgc gtgcggaatt cggccggcag
   693721 cttgccgccc aaagaatcga tcggcgcctt aaatgcggaa atgatcgttg cggtctcatc
   693781 gccggccgca ggtgcgcgcg ccgccgcttt tgctgcgatc tcgtcgagga tgcggccgtc
   693841 gcccgcgccg gcaccctggt ctccgacata ggtccgatag accggcagtg ccgcgatcaa
   693901 ccggcgaatg gcctcaccgg tctgctcgtc ccgatccgga gctccattgc cggtgaagcg
   693961 agcgaccagt ccggtcagcc gccgcacttc cgtattaaag ttgcggccca ggacctgaag
   694021 cttgcatccc gtgacggccg cctcggccgc agatcgcctt tgctcgcttg aaagccacga
   694081 ggacggagtg tcgtcggaga gcaaatccgc cagtgctgaa atgaactcgt agcccgttgt
   694141 tccctcgacc ggccagccgg ccggcagcgt ttcgttctcg cccagtattt tctcaacgat
   694201 gatgtaggtc ccgtcaccgg tctcctcccg gagccggtcg agatagccct tcgggtcggc
   694261 aaggccgtcg atgtggtcga tcctgagccc atcgacaagc ccttctcgca caagtgcgag
   694321 cgtgaggcgg tgggtatcgg cgaagaccgc gtcatcctcg acgcgcatgc cgacgaggcc
   694381 ggctatttcg aaaaatcgcc ggtagctgag cttgtcccgg gcctcccgcc agttcatcag
   694441 ctgccaggat tgcatccggt gcagacggcc gagctgctgt ttgtctgcgg agagccgagc
   694501 gagatactgg tcgagctcgg cagcgagcga tggcgtcgcg acgacagcgg cgatttccgc
   694561 gtgaaactgt gcggcggtct tccgttcggc cgtgccggcg atggccgcga ttctttcgag
   694621 cacggcattg ccgcttcgag gtattgccgc ataggtggcg ggattgagcg gataaagggc
   694681 accgtaataa tcgagcgcca ggcagcggcg ttcatggtcg tatgcaaggc gcagattgcc
   694741 ggccgcgacc tcgtcttcaa acgaccggcc caggaaggga agcgtcaagg gcgctcccca
   694801 gtcgatgtcg aaatggtcgg caaactcgct gacccggccc cattcgatca cgctgtgcca
   694861 ccaatcattc tcaagatgcg cggccatgtg attgggcacg atgtccagaa cgagacctag
   694921 tccttcaacc ttcagcgtat gaacgagccg cacaaaacca tcgtagccgc ccagcgacgg
   694981 gtcgatctcg tcatagcaaa cgatatcgta tccatgggtg gacccgcgaa cggcggtgaa
   695041 gaggggagag gcgtagaggt gagatacgcc gagcccgacg aagtgcggga tcaactccac
   695101 ggctttcgcg aagtccatcc cgttgcggaa ctggagtcgg taggttgcgt cgggcagatg
   695161 catggcgctc ttgcacttgt ctggcggtaa caccgcgacc ggtgctttgt tccccgacag
   695221 aggccacgaa agcaaagtct tcttgttcgc gtatcgggaa tagaatgccg ttcctttagt
   695281 ctactaagat tatagatttt gatgagtatc actgaagcgt aaatcacacg gggagttaaa
   695341 gcgatgccgc agtcacgagt ggtgggaatt tcaggcaata tcacgcgtcc gtccaaaaca
   695401 cgcgcattcg tggaccacat cgtccaccgg ctggcggtcg atgccggcgc ttcggcgcag
   695461 accttcgata tcgaggattt cggggcttcc ttgctgcccg cgagacggct cgatgaactc
   695521 gcgccggaag cgcgctatgt cgtcggtcag atcgtcgcag ccgacattct ggtggtcggc
   695581 tcgccgacct tcaaaggaag ctacaccggt ctcttcaagc acgtcttcga cctgctggat
   695641 cccgcttcgc ttcgcggcaa acccatcatc ctctcggcta ccgggggcgg ggaacgacac
   695701 tcgctgatgg tggagcacca gatgcggccg ctgttcggct ttttcgaagc cctggcgatg
   695761 ccgaccgcga tctacgcttg cgacaaggac tttgccgacg gcgctctgat ttcggaggca
   695821 attcatgcgc gcgtcggaag ggcgatcgaa gaagcaacgc aagcgctcgc gcgtcccggc
   695881 aaggcaaggc tcgcggccta accgcgcaat tgaaccacat ccattggagg cagcaatgac
   695941 cagacagata aagctcggag cctttctccc cggcggcggc cagcatattg ccgcctggcg
   696001 gcatcccgac gctcccgcag acggtgccac gaatttccaa ttccacagaa ggcttgccga
   696061 gactgcggag cgcggcctgt tcgacgccta ttttcttgcc gacaacctct ccgtcggact
   696121 tggcggccgc gaaggcggca atgcgaaaat cgccggtttc gagcccgtca ccctctttgc
   696181 agcactcgcg ccgctgacga cccatctcgg cttcatagcc acggcatcga cgacctacga
   696241 agagccatac acgctcgccc gcaagttcgc ctcgctcgac cttctttccg acgggcgggc
   696301 aggctggaac gtggtcacat ccgccggcga cgagacggcg cgcaacttca acagggaatc
   696361 gcagccgagc cacgccgaac ggtaccagcg cgcacacgag catgtcgaga ccgtcaaggc
   696421 tctatgggac agctgggaag acgacgcttt catcagggac aagacgactg gccgcttctt
   696481 cgatgccggg cgtgttcacg acatcgatca caggggcaag catttcagcg tcaaaggacc
   696541 gctgaacgcg ccacgtccgg ttcagggaca cccggtcgtg gtgcaggcgg gtcaatccga
   696601 agacgggcgc aagcttgcgg cggcaagcgc cgaggtgatc ttcaccgccc atcagagcct
   696661 cgcttcggcc caggaattct accgcgacat caaggcgcgt gtgaagcgcg ccgggcggaa
   696721 cccagaacat gtgctgatca tgccgggggt ggctcctttt gtcggccgga ctgaggaaga
   696781 ggcccgctcc aaatatgaag aactgaatgc gctgatcgtg ccggaggacg gcgtggcgct
   696841 gctgaacggc ctgaccggcg gcacgctcga cctgacggga tatccgctgg acgagccctt
   696901 gcccgtcagc gatgagacgg aggggatgaa aagccggcag gcgctgatcc ggaagatcgc
   696961 ggacgagcat ggcttcacca tacgccagct ctatcagtgg atcgcgaccg cacggggtca
   697021 ctacaccgtc gtcggcagcg ccgagcaggt cgccgatcag ctcgaggagt ggttcctcag
   697081 cgacgccgcc gacgggttca acatcctgcc gccatggctt ccgggtgcgc tcgacgattt
   697141 cgtcgatctg gtcatcccga tactgcagaa gcgcggtctg tttcggaccg cttacgaggg
   697201 ccggaccctg cgggaaaatc tcggtcttcc ccgtccggcg aacccatgga ctttgggacg
   697261 cgcgaccgtt caggcggccg agtgagcgag gagacacgaa tatgagcttg caggaactcg
   697321 acaggtcgat cgtccacgac ggcggcagcg tcagcgcgaa agcggatgag tatcttcgcc
   697381 ggtcaggtac agccgccggt ggctggctgt cgcgctacgg actgctcatt gccgttctgg
   697441 cgctctggca ggcagccagc accgccggct ggatcaaccc ggcagtgttt ccgtccgtcg
   697501 gtgcgattct ttccgcgctc tggacgggaa tttccggcgg agccttgctc gatgatatcg
   697561 cagtcagcct tcagcgctcc ggcaccgcct tcgccggcgc tgtcgtcttg gctataccgc
   697621 tcggtctctt gatggggcag gtccgttcga tcgagaacgc gctcgatccc gtcctccagc
   697681 ttttccgcca gacgtccgcg ctcgctctct atccggtttt cattcttctt ctcggacttg
   697741 gcgaggcgtc gaaagtattc gtcatcttct gggcgacgct tttcccgctg ctcctgagca
   697801 ccatcagcgg ggtcaaggag gtggattcga agctaatcga gatggcgcgt gtctacgggg
   697861 cgtcgcgtct gacggtattc cgtcgcgtgg ttctccccgg agccgttcct tcgatcttcg
   697921 tcggcctgcg cttgagtgca acgaccgccc tgctgctgct gatcgcttcc gagatgatcg
   697981 gagccaacaa gggcatcggg ttccaggtca tgaatgccca gtacaacttc cagatcccgc
   698041 tgatgtttgc ggcgatcttc atcctggccg ggctcgggct cctttccaac tacgcgctgg
   698101 tctttgcgca gcgccgcctc tgccgctgga gcgacgcctc gaactaacgg ccgccccggc
   698161 attcgaaact tcctgatcac ggaaaaggtg acacatgacg atctccattc gcgccttcgc
   698221 attgggcagc ctggtcgcaa tcggcttctc cagccttgcg gcagcggaag ctcaagaacc
   698281 ggtgacgctt cggtttctcg cgagccaggg cagcttatcg ccgcacgaac tcgcctatga
   698341 actcggctat ttcgatggcc tcggaatcaa gctcgagaat gtcggttatg cgggaggcgg
   698401 accggcgtcc ctgttcgcgc ttgcttccgg cagcgtcgac atcggctcgg cggcgacggc
   698461 agccgtgatc aactcgattg ccggcggcaa cgatttcgtc gcggcctttc cgaccaatgg
   698521 catcaacgag caggtcaaga gcatcttcta cgtgctcgag gacagcccta tcaggacgat
   698581 cgaggatatc gcgggtaaga cgatcgccgt gaatacgctt ggggcccatc tcgactacgc
   698641 gatacgcgag gcgctgcata gcaacggcct gcccgaaaac gcagccaatc tcgtcgtcgt
   698701 gcccggacct cagctcgaac agacgctccg gtcgaaccag gtggacatct ccgccgtcgg
   698761 atactggcag gcgacgttca atgggcagct cgtcgccaat ggcggagtac gcgcggtctt
   698821 cgacgacacg gatgtgctcg gcgagattgc cggaggtttc gcggttctgc gccgcgattt
   698881 cgtggaaaag aatccggacg cagccaggcg cttcgtagag cagtccgcgc gcgccgccga
   698941 ctggtcgcgt gagcatccgg acgaagcacg tgccttgctt gcccgcattc tgaccgagcg
   699001 cggcgagaac ggcgatctcg cgaagcattg gaccggattc ggcctgcgga aaggcgcgaa
   699061 agcgaccgag cgggatctgg atttctggat cggcgtcctc gaacgcgagg gcagcctgcc
   699121 ccgaggcaaa tacaaggctt ccgatctttt gttccggccg gacgccaagt ccgccgcgtc
   699181 gaattgaggg tggcgacatg gctgaagtaa gaagcctacg caggggggag gtggcgctcc
   699241 gcgacctctc gaaatccttc cggatcaatg gaaggccgct cagcgtcctc aggaacctta
   699301 atctggatat ccggtccggg gagtgcctcg cgatcgtcgg ggcaagcgga tccggcaaga
   699361 cgacattgct gcgtgttctc gcgggcctcg aaaccgccga ttccggccga gctttgatcg
   699421 acggtcgccc ggtcaccggc gtcggcaggg agcgcgcggt cattttccag gagccgcggc
   699481 tgcttccatg gctgaccgtc ctcggcaacg tggccttcgg ccttgaggta cggggcgagg
   699541 atccgggacg cgccgacgaa cgcgcacgcc actatatcgc ccttgtaggc cttgccgatt
   699601 ttcaggacgc ctatccgaaa cagctttcgg gtggaatggc gcaacgggtc gggcttgcgc
   699661 gggcgctgac ggttcagccc gaaattctgc tgctcgacga accgttgggc gcgctcgatg
   699721 ccatgacgaa gctcacgatg cagcaggaac tggagcgcat ctggcgcgag gagaatgtga
   699781 ccatggtgct cgtcacccac gatctcgagg aagcgcttta tctcgcggac cgtgttctga
   699841 tcttaccgaa gcaaaaggac gcttcgccgc gcctgatcgg gatcgatctg ccgcgaccgc
   699901 gtgatcgcag cgaagcgcgc ttcgtccgat accgtcagga gctgcttcgc gaattcgggc
   699961 tgcactgagg tctcttgcag ccggtgaccg gacccgcgat gcaagcctgc ttgctctgcg
   700021 aacagtatcc tcgggcctga ccggatcaag cccgaggata acgagggaag gacgcccttc
   700081 gtgttccgca taggtccaaa agcaataacc ggggaattat gaatttccgc ccatatttca
   700141 tttttgcatc accgtttgac atggcagact gcccgccatc aatgcgattg atcttgaatg
   700201 aagcgacgcc ggtcgggagt gacggatgtc gcggggaggg aaatatgaga aggatcattc
   700261 tggccgcgct cgcggccctg gtaacgagcg cggcggcgca tgccgatgcg atcaaggtcg
   700321 gcgtcgttgg gccattttca gggccttttg cgctgcaggg aaagaacttc aaggcgggaa
   700381 tcgacgccta tatggcgctg agcggggtca aggtcggcga agacgatatc gagatcatct
   700441 atcgcgacgt accgcaggcg gatccggccc agtccaaggc gctggcacag gaactggttg
   700501 tcaaggaagg cgtgcagtat ctcgccgggt tctatttcac gccggatgcg atggccgtca
   700561 cgccgttgct cgagcaggcg aacgtgccgc tggtgatcat gaatgccgca acatcggcga
   700621 tcgtcaccaa gagccccctt gtggtgcgca cttccttcac gctttggcag acatccacgc
   700681 cgatcgccaa ggtggcgagg gaagccggcg tctcgaagat tatctcggtc gtcagcgact
   700741 acggcccggg catcgacgcg gagaacgcat tcaagacggg cttcgaagcc gtgggcggcc
   700801 aggtcgtcga ggcgatccgc atgccgctgt cgaccaacga cttctcgccg atcatgcagc
   700861 gcatcaagga ctccggcgca gaaggggtct ttgccttcct gccgtccggc ccgacgacgc
   700921 tcggcttcgt caaggctttc aacgaaaacg ggctaaagga cggcggcgtc aaattcttcg
   700981 cccccggcga tctcacacag gagtccgacc tgccggcgct gggtgatgcc gcgctcggcc
   701041 tgcaaacgac tttccactac tccgtctcgc atgattctcc cgagaacaag gcgttcgtcg
   701101 aggcggccgc caaggcgatc ggcaatccga ctgagctgtc cttcccctcg gtcggcgcct
   701161 atgacggcat gcatgtcatc tataagatga tcgaggcgac aggaggcgag cagaacgctc
   701221 agaaggcggt cgacgcggtc aaggggctct cctggacgag cccgcgcgga ccggtttcga
   701281 tcgatcccga atcgcgccat atcacgcaga acatctatct gcgcgaggtc tcaaaggccg
   701341 acgatggcac ctattacaac aaggaaatcc agaccttcga gaaacagggc gatcccggcc
   701401 tcgcggcgct gaagtgagca accggccagt ctcgctgttt cacacgcggc tgtgcccggc
   701461 agatcactca ttcctgtgac gggcgcagga agaggagggg aagagcaacc ttgccaatcg
   701521 acaggatgcg atcatgcaga ccatcttcag catagcggtc gatgcgctcg cctatggcat
   701581 ggtgctgttc gtgatctcga tcggtctctc ggtcaccctc ggcctcatgc gtgtcgtcaa
   701641 tctcgcgcac ggcgcattcg cgatgatcgg aggctacatc gcatcctatg cggcgcggga
   701701 ccttggggtc ggctatgggc tcgcggtgct gatcgccgtt ttcggcacga tcgtcatcgc
   701761 cattccgatc gaacgcttgc tataccgccg gatctacggc cgcccggaat tgacgcaggt
   701821 gctgatgacg atcggcatca ccttctgcat catagggatc gccaattacg ttttcgggcc
   701881 gaccctcaag acgatcccac tgccgccgag cctgcagggc tcggccgatc tcggcttccg
   701941 ttcgatcgcc gtgcaccgga tcttcgcgat cgtctgcggc ctctgcgtcg ccgcggccct
   702001 ctggtatgcg atcgagagga ccgctttcgg ggtcagatta agggccgccg tggatgatgc
   702061 ggccatggcg gcggcactcg gcgtgcgcac ggaagtcatc tacgccgtga gcttcgcggt
   702121 cgccgtcgga cttgccgcat tcgggggtgt cgtcggtgcg gagctgttgc cggtggagcc
   702181 ctattatgcg ctcagataca tggtcacctt cctggtcgtc gtttccgtgg gtggtgcggg
   702241 atcgatcccg ggcgcgcttg ccgcctgcct gctgcttggc ggcatcgata cgaccgggcg
   702301 ctatctgatg ccggagttcg gggagttctt cttctacctg gccgtcatcg cgatcgtctg
   702361 cgtgtttccg cgcggccttg ccggaaggat gaagtaagtg accacggcta cgacgaacca
   702421 ggcagaggcg ccccttcttt cgggcaggca cgggctcggc cgtgatcttg ccgctctcgc
   702481 cgtgatactt gtcctggccg tcatcggtta tcttctgttc ccgaacaatc tggcgctgct
   702541 cacgcgcatc atggcgatcg ccctcctggt tctctcactc gacctggtga cgggctattg
   702601 cggcgtcgcg accctcggcc atgcggcgct gttcggcagc ggcgcttatg ccgccgggat
   702661 cgcggccgtt catttcggca tcaccgatcc gctccttatg gtcgccgccg gcatcatcgg
   702721 cggtgcgctt gccgggctcg tctgcggcgt cgtaattttg agggcccacg gcctcccgca
   702781 gctcgtgctc tcgatcgccc tcatccatct gttccatgaa ttcgccaaca aggcgtcgtc
   702841 ctggacgggc ggcagcgatg gattggcggg catcgcgccc gatcctcttt ttggaatttt
   702901 cgcttacgac ctgtggggcc gcacggccta tgtcttcgca gtcgtgctgc tcgcaatcgt
   702961 cttcatgttc cttcgtctcg tcgtgcgctc accctttggc atgctctgcc gcggcatcaa
   703021 ggaggacccg atccgcattc aggcaatggg cgggtcgccg acgatcgccc tcctcaagat
   703081 gtatgtaatt tccggtgcgg tcgctggcgt cggcggggca ctcaacgccg tctcgacgca
   703141 ggtcgtcggt ctcgacagcc tctccttcac gctctcggcc gaaagcctgg tcatgctcgt
   703201 gctcggcggc accggctcgc tcttcggggc cgtcaccggt acgatcgttt tcatgctctt
   703261 cgaagatctc gtctcggcgg ccaacccgtt tcattggctc accatggtcg gagccctgtt
   703321 gattgcggtt gtgctctttg cgccgaaagg gctttacggc acggtcgcag aagtcctcgc
   703381 gcggcgacgg ggggcgggcc gatgagcgcc atattcgaag tcagaaatct caagcgctcc
   703441 ttcggcggcc tcgccgtcac caatgatgtc agcctttcca tggcaccggg cgaccgcgtc
   703501 gccctgatcg gaccgaacgg tgccggaaag acgaccttcg tcaacctcgt caccggcaat
   703561 ctggagccgg atgccggaga ggtaaggatc ggcggcgaat ccgtcaccaa cgtcaatgca
   703621 atcgaccgcg ttcgccgcgg cctcgtccgt tcgttccagg tgacgcgtct attccaggac
   703681 atgacgcccg ccgagcacgt ggcgctcgcg atcctgcagc gcgacggccg ggcaggccgc
   703741 atgttcggca atttcctgtc gatgcccggg gtgatggcgg aggtgggcgt tctcattggc
   703801 aagctgggtt tgcgcgatct ggcgcaccgg ccggtgcgcg agatcgccta tggccagcag
   703861 cggctgctgg agatcgcgat ggcgctggcg ctcaaaccga gggtgctgct gctcgacgag
   703921 ccagcagccg gcgtgccgca gagcgacacg ggccgcatcg agcgggcgct cgccgatctc
   703981 ccagatgacc tcgccgtgct gatgatcgag cacgacatgg atctcgtctt ccgcttcgcc
   704041 aagcgcgtga tcgtgcttgc tgccggcacg gttatcttcg acggctctcc agccgacgtc
   704101 accaaagatc cgcgtgtgcg cgaagcttat ctcgggagct atgccgatgc cagcagcgcc
   704161 gcttgaggtc gacaatctct ccgccggtta tgggccgacg cgggtgctgg aaggaatttc
   704221 cttttccgtg tctgccggcg cgaagcttgc ggttctcggg cgtaatggca tgggcaagac
   704281 gacgctgctc gctacgctcg ccggccagac gcgccgttat gacgggcgca tccgtatcgg
   704341 cgaggccgat gtcaccgcgc tgtcgagcgc atcacgcgcg ctgaaaggcc tcggcttcgt
   704401 gccgcaggcg cgctgcgttt tcccgtcgct gacggtcgag gaaaatctct tcgtcggcct
   704461 caagggccgt gcgaagacgg cgctgaacga agcttacgag atgtttccgc gcctctatga
   704521 gaggcgcagg aacttgggct cgcagctttc gggcggcgag cagcagatgc tgtcgacagc
   704581 ccgctcgatc ctcggccggc catccattct gcttctcgac gagccgctcg aaggactggc
   704641 cccggtcatc tgcgaggaac tgatgaaagc cttcgcccag cttgcaagga ccggcgatat
   704701 gacgatcctg ctcgtcgagc agcgcattcg gagcgcgctc gatttcgccg accgggtgat
   704761 catcctggag cgcgggcggc tcgcatggag cggaacgccg aaggcgcttg tgaaggagcc
   704821 cgccacggtc gagcagctgc tggggattgg cgggttggcg ccgagccctt gatttgccgc
   704881 aatccgacag ccggtcactc taaaccgcct cgcgcacccg ctcccaggcc ttcgtcagat
   704941 ggcgcccgag cacctccgat agcgtgacct cgtcgcgcgc ttctagggcg gcgatcatct
   705001 cttgatgttc ggcaaccgcg gcggcccatt tctccgggcc ctcatggccg atgaagcgga
   705061 tgcgcttcag ccgcgtctgc agcatggcat gcatgtcggc aagcgccgca ttgcgcgaaa
   705121 gccgggcgat ggcggtgtgg atttcctggt tgagcttgta atattgcatc cggtcacccg
   705181 cctcgtagcg gcgcaccatt tcgtcgtgga gcgcgcgaac ttcagcgatc tccgcatcgg
   705241 tcgcggtctc gcaggcaagc cggcctgcga gctcctccag cgtctgcagc accgtcagca
   705301 tgtcccggac gtccttggcg ctgaaacgct tgaccacggc gccgcggctc ggaacgagct
   705361 cgaccagacc ttcgctcgcc aaatatttga tcgcttcgcg cagcggcgtg cgtgatacgc
   705421 cgagctgctc gccgagctgt ccctcgtgca ggcgggttcc tggcggaaga ttgccctcga
   705481 ttatcatgtc acgcagatgg ccgaccagag tgtcgtgcag tgcggtgcgc cgaatgggtc
   705541 cgggaccgcc tacgggccgc tgctccagtg atttgatttc gttcatttgt ctcgtctgag
   705601 cctcggaccg ccgcgcggtc tcccccttga gtacgtccga ttgaatcggt gccttctcag
   705661 tcaagcatga agactgcctc cgctaccgtc aacagaaaat gctgcataca aaatacaaaa
   705721 gacttgatgc agaattttga atgacgtatg agacgttaaa gcacggaaag cggagggcat
   705781 ctcgatgacg acaccaggag cggacggaac ggaggagcgg cgcaccgtga ttgcgctggc
   705841 gatgggcgac cccgccggga tcagcccgga gctgacggcg cggctgcttg ccctttccga
   705901 catccgcgag gcggtgcata tcattgccat cggcgatcgc cgcatccttg atgagggcgc
   705961 ccgggtggcc ggcgtcacgc tggatctgga atcggtttca ctcgattcgc ttgacaggtc
   706021 cggcacggcg cgccacgtct tcgtggatct cgcccatctc gatccggccg atgtagtgcg
   706081 cggagaggcg acgcttgccg gcggcacctt cgccacgcga aatttccgca cggcgctcga
   706141 actcgcccat gccggcaagg ccgaagccgt ctgcttcacg cccttcaaca agaaggcgat
   706201 gcgctttgcc tatccaggct atgacgacga gatccgcttc gtcgccgacg tgctttcctt
   706261 caccggaaaa gttcgtgaat tcaacgttct cgagaaggtt tggaacgcgc gggtgacctc
   706321 gcatatcccg ctcaaggatg tggcagccca cctgtcggtg gatgcgatcc tcgccgaaat
   706381 caatctgacg caggcctgcc tcaaggatgc cggctacgag gaagcgagaa ttgcggttgc
   706441 ggggctcaat ccgcatgccg gcgacggcgg cagcttcggc atggaagaga tcgacatcat
   706501 cgagccggcg gtcgagaagg ccagggccct cggattcaat gtcgaggggc cgttcccggc
   706561 tgacacggtc ttcctcaggg cgctgaagga aggcttcaat gccgtgatga ccatgtatca
   706621 cgaccagggt cagatcgcca tgaagatcat cggtttcgac aagggcgtga cgatgatggg
   706681 cgggctggcg ttcccgctct gcacgcctgc gcatggcacg gcttacgaca tcgccggcaa
   706741 gggcatcgcc gatatcggcg ccactcgcga ggcgatcctg ctcgccgctc gaatggcgaa
   706801 gaaaaagcgg gcgcttccgg cggctgcctg aattcgcacg ctttcgatga ataccggcgt
   706861 gaggggaggt ctcgcgccgc aatccaactc aacgggagga ccacacatga aaaaatccgt
   706921 atccattgca gcagtcgtag cggccgctgt cggccttgcc gcaccggcat cggccttcga
   706981 gccgaaccgt ccggtcgaat tcgtcgtcac cgccggtccc ggcggcggca ccgatatctt
   707041 cgcgcgcacc atccaggcga tcatcggcaa atacgagctg atgaaggcgc cggtcgtcgt
   707101 caccaacaag ggcagcgccg gcggtgcgga aggcttcgtc tacacggctg gccacaaggg
   707161 cgatccctat aaactcgcct tcggcaccaa caatgcctac ctgctgccgg tccgcgccaa
   707221 ggtgccttat aaatccgagg acctgacgcc ggtcgcttca ctcgcttccg acgagttcgt
   707281 gctctgggtc aacggcaagg cggattacgc gacggctgcc gatttcgtgg ccaaggcgaa
   707341 ggaaggcggc cttaagatcg gcggcagcca gtccaaggac gccgaccaga tcctgacctc
   707401 gatgatcaac gacgcaatcg gcgccaagat cagctacatc ccgttcaaga gcggcggcga
   707461 ggcggccgtt cagcttgcgg gcgagcatct cgacgccaat gtcaacaatc cgagcgagaa
   707521 tctcggtcaa tggcaggccg gcatgatcaa gccgctttgc gtcttcaaga gcgcaaagtt
   707581 tgcaagcgac gccaaggtag ccggcgacaa ggcctggagc gacatcccga cctgcaagga
   707641 agccggcatt ccgatcgaaa actacgcgat gccgcgcacc gtctggctgc cggccggcgt
   707701 cgagcatgat gtcgtccagt tctatgcgga tgtcctgcgc aaggtctccg agacgccgga
   707761 atgggagaaa tatcttgccg acagctcgca gtctcccggc tttgtgacgg gcgacgaact
   707821 caaagccgtc atcgaaaagg atggcgcgac ggtcggcgaa gtgctgaagc gcgaaggctg
   707881 gctcgccaac taagtacccg gtcaatgggc gcttgggacc cagggaagag gatgcgggta
   707941 gaaccgcatc catcctcggc ctgccggacg cccattctcc gctcggaaag gtcatgatca
   708001 tgagtgagaa cagtgcgaat gggatcagcc gctttgctgt ggaacttggc gtcgccgcgc
   708061 tgacaggtgt ctttgggatc gctgtctgct acggctcact cgatatcggc gcgggctgga
   708121 ccgatatggg tccggatgcg ggctatttcc ctttctatat cggcctgctc atcgttctcg
   708181 gcagcctcgc caatatcgcg cacgcattct tcaagcatcg cggtacgggc gaggtcttcc
   708241 tcgacggcgc ccgtaccagg gtggtcgcct ccttcctgct gccgatcgcc gccttcgcgg
   708301 gcgtttccgc gtggctgggg ctttatgtcg gaacggcgct ctacattgcc gcgaccatgc
   708361 tcttccaggg gcgctacaaa tggtggatct cgttgccggc gggactcggc gtctcgatct
   708421 tctttttcat cgttttcgag atcggcttcc aggttccgct attgaaggga ccggtcgagg
   708481 cttggttcgg aatttactga cccgcaaggg tgcagtgctt gcgggaggaa tgacatggaa
   708541 aatatcggtc tcctgatcga tggcttcggc cacatcctca gctggaacca tatcctgctg
   708601 atggtcgtcg gcgtgacgct cggcatcctc gtcggggtgc tgccggggct cggggcgcca
   708661 aacggcgtgt cgctgctcct gccgctcacc ttctccatgg accccatctc ggcgatcatc
   708721 ctcttgtcct gcatgtattg gggcgcgctc tttggcggct cgacgacgtc gatcctcttc
   708781 aacattccgg gcgagccctc atccgtcgcg accacattcg acggctatcc aatggcgaaa
   708841 gccggtcatg cgagccgggc gctcacactc gccttcgttt ctgccggcct cggcgcgctt
   708901 gccggggtcg tcatgatcac gctgctttcg ggctgggtgg cgaacttcgc actcaaattc
   708961 tcctcgccgg aatattttgc cgtttatttt ctcgcctttg cgagcttcat ctcaatgggc
   709021 gcgcagtcgc ctttcaagac gctcgtgtcg atgatgctcg gcttcgctct cgcctccgtc
   709081 ggcatggata cgatctcggg caatctgagg ctcaccttcg acattcccga actgatcaag
   709141 ggcgtcagct tcctcatcgc cgtcatggga ctcttcggta tcggcgaact tctgctgacg
   709201 acggaagagg ggctgcgctt cgaaggcatc aaggcgcggg tgcggctgtc cgaaatcggc
   709261 aggacgctga tcgagatccc acgctattgg ctgacgatcg cccgctcgac gattatcggc
   709321 atctggatgg ggatcacgcc ggccggcccg accgccgcct ccttcatgag ctatggcgtt
   709381 gcccggcgct cggcgcgcga caattcgatg ttcggcaagg gcgatccgcg cggcatcgtc
   709441 gcgcccgaga cggccgacca ttccgccggc acttcggccc tgctgccgat gctggcgctc
   709501 ggcgtcccgg gttccgccac cgccgcggtg atgatgggcg ggttgatgat ctggggcctg
   709561 acgcccggtc cgatgctctt caccgatcgc cccgacttcg tctggggcct gatcgcctcc
   709621 atgtatctcg gcaatgtcgt cgctgtcttt ctcgtgatcg cgacggtgcc gctttacgcc
   709681 tccatcctgc gtgtgccgtt ctccatcatc ggaccgatca tcgtcgcggt catcttctca
   709741 ggagcttacc aggtcgcaaa ctccgtttcg gacatcttca tggtgatcgg cttcggtctt
   709801 ctcggctacg tcttcaaaaa gctcgactat ccgctggcgc cgctggtcct cgccatggtg
   709861 ctcggtgaca aggcagaaga cgccttccgc cagtcgatgc tgatgtcggg cggcagcctg
   709921 aacatcttct ggtcgaatgg ccttgtctcc gccctgatgg cggttgccct tgcgctgctt
   709981 ctttcgccgc tcgccttctt gctgatcggc agcgtgcgaa aacgcaagaa cgaggtggtg
   710041 gcgcccggcg gtgacggcag tccggcaggc tgacgcggcc tgcgacgata cgtaaatcca
   710101 atctgaagga gttcgccatg gcgccgcgca aatggaaccg tgataactgg ccgattgcgg
   710161 ccgctatgat ccagtacccc aagcttttgc cagatggccg atcggtgcag gaccagtcgg
   710221 tggaggagtg ggcggcgacg ctcgccgacg tcgtcgatgc cggcttcacc gaactggacc
   710281 cgaccgacag ctggatacgg ctggcggacc tttcggcgga acggcttgac cagttcgtta
   710341 agctttcacg gtctcttggc ctcaatatca cggcgatctc cacctctcgg cgcagcctca
   710401 tagacccgga acatggcgcg gaatatcttg cctatggaca ccgggtcatc gaggcggccg
   710461 ccgccgtagg tgccggctcc gtgtccttcg gcttcttcgg cccgctgacg gaggcgcaga
   710521 agaaggtgct ctggttctgg acggtcgacg gggtgaagaa ccccgacgat gcggggacct
   710581 ggcagttggc ggtctcgcgc gttcgcgaac tcggacgcca tgccgaagaa ctcggcgtcg
   710641 aagtctcgct ggagatgtat gaggacacct atctgggcac ggccgacagt tccgttcgct
   710701 tcgtcgagga ggtcggcctg gccaatgtcg gcatcaatgc cgatctcgga aatctcattc
   710761 gcctgcaccg gcccgtggaa cattggcagg aaatgatggc aaaggttgcg cctttcgcca
   710821 aatactggca cgtcaagaat tacaaccgca cggaagatcc ggcatcgggc gtcatcatca
   710881 cccatccggc tccgctcgaa ttcggtctca tcaactatcg ggcggcgatc agaatggcgc
   710941 tggcgcatgg cttcgacagc cccttcctct gcgagcatta cgggggagac ggactctccg
   711001 tcagcgccgc caaccgcgat tatctgaggc gcatactgcc tcgccaagaa ggacattgaa
   711061 ggggacattg cagcgatgac cacgatcttt gacgctccgg aggatttcgc gacgaccgcg
   711121 ctcgcgggtt tcgcggcgat ctatcagcgc aacgtccgcc tggtgaaggg cggcgtcgtg
   711181 cgctcgacca aggtgccgaa gggcaaggtc gccgtcgtcg tcggcggcgg ctcggggcac
   711241 tatccggcct tcgccggata tgtcggtccg gggttggccg acgcggcggt ggcaggcgat
   711301 gtctttgcct cgccctcgac ggccgccgta gctcgcgtct gccgccatgc cgaccagggc
   711361 ggcggcgtac ttctcggctt cggcaattat gccggcgacg ttctaaattt cggggtggcg
   711421 gccgagcggc ttcgctccga aggcatcgac gtgcgcatcc tgccggtgac ggacgacgtg
   711481 gcgagcgcac ccgtggacag ctcggccaaa cgccgcggga ttgccggcga cctcgtcgtc
   711541 ttcaagatcg ccggcgcggc agcggaagcc ggcaaatcgc tcgacgaagt ggaacggctc
   711601 gcgcgctacg ccaatgatcg caccttttcc ttcggtgtcg ccttcggcgg ctgcacgctt
   711661 ccgggcgccg ccgggccgct cttcacggtc cctgatggcc agatggcgct gggcctcggc
   711721 atccatgggg agccgggtgt cagcgaggag ccgattgcga cggcaagcga tctcgcaaag
   711781 ctcctcaccg gcaagcttct cgccgaacgt cccgcaggcg ccagcaaggc ggccgccgtg
   711841 ctgaacgggc tcggctcgac caaatatgaa gaactcttcg tgctgtggac ggcggtcgca
   711901 aaagaactgg cggaggcgtg tgttgaggtg gtcgaccccg aatgcgggga attcgtcacc
   711961 agcctcgaca tgcagggctg ctcgctcacc cttctctggc tgaatgaaga gctggaggcg
   712021 ctctggcgtg cgcccgcgga tgcaccggtg ctgcgcaagg gcgtgatcat tgccgccgag
   712081 ccggcgaccg atgagatcgc ggacgcagac ggtccacaat ctttcgcgcc cgcttcggaa
   712141 gcctcgaagg caagcggcaa gtgcatcgcc cggctgatcg gcaatatagc cgatgcgctg
   712201 aaggaggcgg aagaggaact cggccgtatc gacgcttttg cgggagacgg cgatcacggt
   712261 caggggatgc gccgcggctc ggctgccgca tccgacgcag cacagacggc agtcgcggcg
   712321 ggggcgggtg ctgcaagcgt tctggctgcc gcgggcgacg cctgggccga tcgcgccggc
   712381 ggcacgtcgg gtgcgatatg ggggctggcg ctccgctcct ggagcaatgc attcagcgat
   712441 gaggacaagg cgagcgacgc ggcgaccgtg gagggctccc gccttgcgct cgagggcgtg
   712501 acgcgccttg gccgcgcgcg tgtgggcgac aagacgctgg ttgacgcgct ggtgcccttc
   712561 gtcgagacgc tggaaaggga atccgctgcc ggaaggccgc tcgtagaagc ctggaacgcg
   712621 gcggcaacag ccgcgcagga ggcagcggat gcgacctcgg cgctgacccc gaaactcggc
   712681 cgcgcgcggc cgctggccga gaagagcatc ggccatccgg acgccggcgc agtttcgctg
   712741 gcgctggtgg cacgggttgc aggcgcgttt ttgaaggaag ctgcggccgg ttgataactt
   712801 gcggcgacgg gatagtgtgc ctcacacgca aggcgcctaa ctataccgca ccaagaactc
   712861 ctccgcagtc agctcccgga aatcgtccag cgcatggcgc agcttggcat ggtcccaatc
   712921 ccaccaggcg agccggtcca tggcttcgcc gactctggcc gtgaagcggt cgcggatgag
   712981 tttcgccggg accccgccga cgatcgtgta gggcgccacg tccttggaga cgacggcgcc
   713041 ggcgccgatc acggctccat tgccgacctt cactcccggc agaatggtcg ctccgtggcc
   713101 gatccagacg tcatggccga ttgtcacccg gttctgccgc cgccaggcga acagatcgtg
   713161 atcgggctcc gcatcctccc agtacatcgg cgcgcgatag gtgaaatgat gcagcgtcgc
   713221 tcgccaggtc gggtggttgg tggcgttgat gcgcacggcg gcggcgatgt tgacgaattt
   713281 gccgaccgtc gcgcaccaga tcgagccgtc ctgcatgatg taggagtagt ctgcgaactc
   713341 gacctcgtcg agtcgcgagc gttcccggat ttcggtgaag cggccaagcg tcgaattcac
   713401 gacgctcgca gtcggatgga tgcagggttc gaggccgagt ttctcgctca tgcggcgtat
   713461 ctcctcggcg agaattccga gacgtcgatg atgcggtcgg caactgcctc gcgcacttcc
   713521 tcgtcgtgga aaatgccgat cagcgccgtt cccgccgact ttttcgcggc gatcatctcc
   713581 accaccacgg cgcggttctt cgcatcgagg gaggcggtcg gttcgtcgag aagaaggatc
   713641 ttgtgatcgg tgatgaagcc gcgggcgatg ttgacgcgct gctgctcacc gcccgagaag
   713701 gtggccggcg gcagcgacca gagttccttc ggcaggttga gcttcgaaag cagttcggcc
   713761 gcgcgttccc gcgcgtcgcc ggccgtgaca ccgcgcgcct gcaggggctc ggcgacgata
   713821 tcgagggcgc agacgcgggg cacgacgcgt aggaactggc tgacatagcc gagcgtcgcg
   713881 cggcgcacct cgagcacggt acgcggctcg gccgttgcga gattgaccag ccggccgtca
   713941 tgttcgacca ggatctggcc ttcgtcgacg ccgtaatttc cgtagagcat cttgaggatc
   714001 gagctcttgc cgacgccgga ggggccgccg agtacgacgc attcgccggc cctcaccgag
   714061 aaggaaacat tcgcgaccac cggcaggcgg acgccgtcgc gcaagtgcat ggtgaagctt
   714121 ttcgcgactt ctgagacaac gagcggagta gccatggtta tttccctttg cgcatgatct
   714181 tgaccggaaa ccagggttca cttttcgcga tcatgcgtca gacctgcaaa atcgaggaaa
   714241 cgaggagctg cgtgtagggc tctcgcggat cgtcgagcac ccggtcggtc agaccctgct
   714301 cgatgacggc gccgtccttc atcaccatca tccggtgcga aaggagccgc gccacggcga
   714361 gatcatgggt gacgatcacc gccgccaggc cgagatcgtg gacgagcccg cgaaccaggt
   714421 cgagcagacg cgcctgtacg gagacgtcga gaccgccggt cggctcgtcc atgaagacga
   714481 ggcggggaga ggtgaccaga ttacgggcga tctgcaggcg ctggcgcatg ccgccggaga
   714541 aggcgcgcgg ctggtcgtcg atccggtcct cttcgatttc cacgcgcctc agccagtcgc
   714601 cggccgccgc gcggatattg ccgtagtgtc ggtcgccgac cgccatcagc cgctcgccga
   714661 cattggcgcc ggcagaaacc gtcatcctca agccatcggc ggggttctgg tggacgaaac
   714721 cccagtcggt gcgcatgagg aagcggcgct ccgcctcgct catgcgcgcg aggtcccgat
   714781 actggccatc gcgcatgtgg tactcgacga cgccggaggt gggcatcagc cgggtcgaga
   714841 ggcaggaaag cagggtggtc ttgccggaac cggattctcc gacgatggcg agcacttcgc
   714901 ccggataaag ttcgaaggag acgttgcggc agccgatgcg gcttccatag aatttcgaga
   714961 cgtcactgac tttcagaagc ggcacggcgc tcattctgca gcctcctgac tttccttggc
   715021 ggcgggcgca agcatggcac cggcatggcc gtgcgcgcgc cggtcttcgc aatgatctgt
   715081 atcggagcag acgaacattc gcccgccctt gtcgtcgagc accacttcgt cgagatagac
   715141 gttctcggcg ccgcaaaggg cgcagggcct gtcgaacttc tgcacctcga aggggtgatc
   715201 ctcgaagtcg aggctgacga cttcggtgta gggtggcacc gcatagatgc gtttctcccg
   715261 gccggcgccg aagagctgga gggcttccga catatgcatc ttcggattgt cgaatttcgg
   715321 cgtcggcgac ggatccatga catagcggcc ctcgacctta accggatagg cgtaggtggt
   715381 ggcgatgtgg ccgtttcggg cgatgtcttc atagagcttc acatgcatca gcccgtattc
   715441 ttcgagtgca tgcatcttgc gcgtctcggt ttcgcgcggt tcgaggaagc gaaggggttc
   715501 cgggataggt acctggtaga cgagtgtttg accctctccc agtttctcct cgggaatgcg
   715561 gtggcgcgtc tgaatgatgg tagcatccgc cgtcctcgtg gtgacggcga cattggcgac
   715621 cttctggaaa aaggcacgga tcgagaccgc attggtcgtg tcgtccgcgc cctggtcgat
   715681 gaccttcagc acgtcactgg gcccgaggat cgaagcggtc acctgcacgc cgcccgtgcc
   715741 ccagccatag ggcatgggca tttcgcgcga ggcgaagggc acctgatacc cggggattgc
   715801 gatcgccttc aggatcgcac gtctgatcat gcgcttcgtc tgctcgtcca gataagcgaa
   715861 attatagttg gcgaggtcgt tcattcggcg gcctccttca tgacgttctt gccgccgggc
   715921 tgggcggact cgtattcccg gcgcatgcgc ctgaccaggt cgagctcggc ctggaagtcg
   715981 acgtagtgcg gcagcttcag atgctcgacg aagccggtcg cctggacgtt atccgcatgc
   716041 gagatgacga attcctgatc ctgggcggga gcgacgatgt cctcgtcgaa ttcgtctgtc
   716101 cggagggacc ggtcgaccag cgacatggac atcgccttgc gctcgctctg gccgaagacg
   716161 agcccgtagc cgcgggtgaa ctgcggcggc tgtttggccg agcccttgaa ctggttgacc
   716221 atctggcatt cggtgacccg aacggttccg agcgatacgg caaagcccag ctccggcagt
   716281 tccagctcga cctcgacctc gccgatccgg acttcgccga cgaaaggatg cgtgcggcca
   716341 tagccgcgtt gagtggagta ggcgagcgcc agcaggaagc cctcgtcacc gcgggcgagc
   716401 gcctgcaggc gcagatcgcg cgccatcgga aactccatcg gctcgcgcgt gagatcgccc
   716461 atcacgtgcc cttcgggcat ctggccgtcg ccctcgatca ggccttcgcc gtctagaatg
   716521 tcggagacgc gcatgacatg ttcgccgggc tccttgagtg ccggctcatc gaccgcgtct
   716581 tcgccgatca gcgatgggtc cagaagacgg tgcgtataat cgaaggtcgg gccgagaagc
   716641 tggcctccgg gcaggtcctt gtaggttgcc gagacgcgtc gctcgacctt catcctggct
   716701 gtatcgaccg gttcggaata gccgaagcgg ggcagggtgg tgcggtaggc gcgcagaatg
   716761 aagatcgctt cgatcatgtc gccgcgtgcc tgccgcacgg caagcgccgc aagcgcgcgg
   716821 tcgtagagcg aggcctccgc cataacgcgg tccacggcga ggccgagctg ctcgacgacc
   716881 tgctcgatgg ttatcgaggg cagcgaccgg tcgccgcgcc ggcggtcggc gagcagccgg
   716941 tgagcattgg caatggcggc ttccccgccc ttgacggcta catacatgcg cttactcccg
   717001 ctcgagtttc gtggtgcgcg gcaggcagag cacggtctca cctgacgtca ctacgagatc
   717061 tatgccgcgc ggaaagatcg cccggttggc cgtccagaga tcaaggaaca cgtcgggcaa
   717121 gcccttcggt gcgatgacga tcccgttctt gattcccggt cccctgccga tgagcggctg
   717181 tccgccttcg agcgcttcca cctcgacgac aagagtggtg gaacggtcgg gatattcctg
   717241 cgagccgagg ccgaactggt cgaagccagg cacggcagcg cccttctcga agaaggcgaa
   717301 gcgggcctcg ttcttcgtgt cggtcaccgc ggcgccggtg tggaaggcga tccacttcgg
   717361 cgctgcggat ttggagagcg ccggcgatag ccagaccggg gtgtcatggt cgcagagtgt
   717421 cagcgcgacg gctccgctgg cccctccgag aggcgggggc ggggaggccg ctgtggagag
   717481 gcggccgatg gtgcccgggc gtgcgaagca gtccatgaga gtccggaaca cggcctgggc
   717541 ttcgaagacc gattcggcga aggcgccgcc atagatttgc gattgggtgc tcatcaatct
   717601 tctccgcgga ccatggtgaa gaaatcgaca cgggtcgcgg ccgtttcctc ggccttgcga
   717661 cggtcttccg catccaggcg tgcagcaatc ctctcgtgga gcgcctcgac gccggcgcga
   717721 tatgcgtcgt tctggaagag agcgtcgaaa atcgccgcaa aacgggcgcg ttccttgtcg
   717781 gttccgagca actgtccgtg gccgacttcg ccggtggcga gcctgacggt ggcgcgggaa
   717841 acggtggcct cgccgagatt gaagggagcg ccgccaccgc ccattcgtcc gcgcaccatc
   717901 acgagccccg tctccggacc acgcaccggc gcgacgtccg gtttcgagcc gattgccccc
   717961 caggcagcgg aaagctcacc gagcgtcgcc cgcgccagaa gccgcatact ctcgcggcgc
   718021 cgggcgatga tctgcgcgtc ctcgcccgtc ctcgctgctt cagtcgtgac tgcttccatc
   718081 ttcgcactcc aaaatgtcta ttgatctaga caactataca tcttatagct ttccatagcg
   718141 ttcgcaaatg acaggcttgt gacatttgcg cagaaaccgg ggcgaagacg atcgtgatga
   718201 agactgttga aagacagacg ggggtggcgc tgtggcgcca gatcgccgac cgaatccggc
   718261 tggcgataag caatggcgac tatgacgcga cgggcaaggt tccgccggag acgacccttg
   718321 ccgcccaatt cggcgtcaac cggcacactg tgcgcagcgc gcttgccgca ctctccgaag
   718381 aggggctggt gcgcgccgtg cagggccgcg gtacgatgat agagcgcaag gagcgcgtca
   718441 gctatccgat ctccaggcga acccgcttct cccaggggct cggccggcag gtcagggaga
   718501 tcggaacgga actccttgaa cacatgcagg tgccggcgag cggcgacatt gccgaagcac
   718561 tcggccttgc cgccggcgcc cctctcattg aactcagtac cgtcagcagt ggtgacggcc
   718621 gaccgctctc cacggctgtc agctattacc ctgccgagcg cttccctgat atggcggagg
   718681 agtatgcgcg gctaggttcc gtgaccaagg cctttgccgc gcatggcctc gcagattatg
   718741 tccgcgtctc gaccgagatc gtggcgcgtc atgcagatgc gcaggaactc gttctgctga
   718801 agctttcgcc cggcgcgatc gtcatggagg cgcaatccgt caatgcggat ctctcgggcc
   718861 ggcccgttga atacgcgcgc acgcgcttcg ccgccgaccg gatgaagctc aagattgaga
   718921 cctgaacgga ttacaggttt cgccgcttgc cttcgatcag atccagaata gcgcgcgcgg
   718981 cgtcgagcac gtgggtgccg gggccgaaga ccgctgaaac gccgttttcc atcagatacg
   719041 cgtaatcctg ccggggaatg acgccgccgc agaccaggat gatgtcctcg cggccgcgct
   719101 ccttcagtgc ctcggcgagt tgcggcatca gcgtcttgtg gcccgcggca agcgatgaaa
   719161 ccccgagaac ggtgacctcc tcggcgagcg ccagttcggc cgcctcctcc ggcgtctgga
   719221 acagcgggcc tgcgacgacg tcgaaaccga tgtcaccaaa ggcggaggcg atcaccttgg
   719281 acccgcggtc atgcccgtcc tgcccgagct tggcgaccat gattttgggc ttgtgcccca
   719341 gccgcttcgt cacctcgccg agccgcccgg ccagcacgcc gagctcgggg tcgccctcga
   719401 aggcccggcc gtaaatatcg gtgacgactt ccggcacggc ggtgtaatcg ccgaaagcct
   719461 cgcgcatggc gtcggtgatt tcgccgacgg tggcgcgtgc ccgcgcagcc tcgagcgcgg
   719521 cggcaagcag attgcccttg ccgctgcgcg ccacatcggc cagcgtgtca agcgcttcct
   719581 tcatcttctg tgagttgcga cggcgcctgg tctcctcgat ccgcttgatc tgtgccgtcc
   719641 ggactgcggc gttgtcgatc tggagaatgt cgatcggctg ctcgttctcg agccggtacc
   719701 tgttgacccc gacgatgacc tcctcgccgc ggtcgaccgc cgcctgacgt cgggtcgctg
   719761 cctcctcgat cagccgcttc ggcaggccgg cattgaccgc tttcgtcatg ccgcccaatg
   719821 cctccacctc ctcgatgagc gcccaggctt tttcagcaag ttcgttggtc aggctctcga
   719881 cgtaatagga gccggcaagc ggatcgacga ccctggtcac tccggtttcg tgctgcagga
   719941 tgagctgcgt gttgcgcgcg atgcgggcgg agaaatccgt gggaagtgcc atcgcttcgt
   720001 cgaaggaatt ggtgtgaagc gattgcgtac cgccgagcac tgccgacatc gcttcgaaag
   720061 cggtgcggat gatgttgttg taaggatcct gttcctggag cgatacgccc gacgtctggc
   720121 agtgcgtccg cagcatcagc gaagacgcct tctcgggttt gaactccttc atgatccgtg
   720181 tccagaggag ccgagcggcg cgcagcttcg ccgcctccat gaagaagttc atgccgatcg
   720241 cgaaaaagaa ggagagccgg ccggcaaaat cgtcgacatt gaggcccttg gcgagcgccg
   720301 cgcgcacata ttcgcgcccg tcggcaagag taaaggctag ctcctgcacg agcgtcgccc
   720361 cggcctcctg catgtgatag ccggagatcg agatcgaatt gaacttcggc atctccttgg
   720421 ccgtgtattc gatgatgtcg gcgacgatcc gcatcgaggg ttccggcgga tagatatagg
   720481 tgttgcggac catgaactct ttgagaatgt cgttctggat cgtcccggag agcttgtcgc
   720541 ggctgacacc ctgttcctcg ccggcgacga tgaaggaggc gaggatcggg atcacggcgc
   720601 cattcatggt catcgagacg gagatcctgt cgagcgggat cccgtcgaac aggatcttca
   720661 tgtcttccac cgagtcgatc gcgacacccg ccttgccgac gtcgccctcg acgcggggat
   720721 ggtcgctgtc gtagccgcgg tgcgtggcga ggtcgaaggc gacggagaca ccctgttgtc
   720781 cggcagcaag gttgcggcgg tagaaggcgt tcgaggcttc agccgtcgag aaaccggcat
   720841 attgccggat cgtccagggc cggccggcat acattgtggc gcgcggaccg cgcaggaaag
   720901 gttcgaaacc ggggagcgag ttgagatcgc ccatgcctga ggtgtcatcg ctcgtataga
   720961 ggggcttgac gtcgataccc tcaggcgtgt gccaggtgag gctctcgggg ccggccttga
   721021 gttctttctc ggcgagggct tcccaatcct tgatggtttt atcgggcatt ggcttgctcc
   721081 atcgaagcgt agtcggcagc ggtaagagac acccacgtcg gcaccgcttc catcactcga
   721141 actccatgat caactcgtcc acggccaggc tcgccccggc ttcgatcgcc acgcgcttca
   721201 cgatcgagcg tctttccgcc ctcaatatat tctccatctt cattgcctcg acgacggcga
   721261 tcgcctgtcc ggcctccact gtctccccgg ccttcaccgt gatcgacgtc actacccccg
   721321 gcatcgggca gagcagcatc ttcgacgtgt ccggcggcag cttcttcggc atcagccggg
   721381 cgagttcggc aatgtgtggg cttctgaccc gtgcaacgac gtcgatcccg cgccagcgca
   721441 gccttattcc ggtgccggca agctcgacct tcacgctcat cggctgattt tctatgttga
   721501 aagcggcacg ggtgcgaccg ggggtccagt cagttgcgac ggagacagat gtcccgtcgg
   721561 caaagcgtac ataggtgccg tcggcggaag cttcgcatgt gacctgaatt tcgtgcccgt
   721621 cgaggcttgc cacccattcg tgaccgatga cccggcgatg gttgccgatg gtgcccgaga
   721681 tgcggctggc gcgctcctgc agcgtctgat tgacgctcac cgcgatggcg gcgagtttgc
   721741 gcgccgctgt gtcgtccggc accacgccct gaaaaccgcc ggcaaactcc tcggcgatat
   721801 aggccgtggt cagccgtccc tcgcggaaac gatcctgctg catgacggct gcaaggaagg
   721861 gcaggttgtg gccgacgcct tcgatctcga acgcgtcgag cgcatccgcc atcgcccgga
   721921 cggcggtcgc ccggtccgga ccccaggtgc aaagcttggc gatcatcgga tcgtaataca
   721981 tcgagatctc gccgccttcc aagacgccgg tatcgttgcg aatgacggta ccgtccgccc
   722041 gcgggccttc ctccggcggg cggtagcggc tcagccggcc gatcgaagga agaaaattgc
   722101 ggtaggggtc ttccgcatag agccggcttt cgatcgccca tccgtcgagc ttcacatcct
   722161 tctgtgcaaa ggcgagtttc tcccccgccg cgacgcggat catctgctcg acgagatcga
   722221 ggccggtgac gagttccgtc accggatgct cgacctgcag ccgggtattc atctcgagaa
   722281 aatagaagtt tccgcgggcg tcgacgatga actcgaccgt gccggccgaa aaataggcga
   722341 cggcctttgc cagcgccacc gcctgctcgc ccatggcgcg gcgcgtcttc tcgtcgagga
   722401 agggcgaggg cgcctcctcg ataaccttct ggttccgccg ctggatcgag cattcgcgct
   722461 cgcccagata gacgatgttg ccatgcttgt cgccgagcac ctggatctcg atgtggcggg
   722521 gctcggtcac gaatttctcg atgaagatgc ggtcgtcgcc gaaggaactc ttcgcctcgt
   722581 tcttcgatga ctgaaagccc tcgcgtgcct cgtcctcggt ccaggcgatc cgcattccct
   722641 tgccgccgcc gccggcagac gcctttatca tcaccggaaa gccgatcgaa gcggcgatgc
   722701 gtgcggcctc gtccgcatcc ccgatcagcc ccatatggcc gggaacggtg gaaacgcctg
   722761 cttcggcggc aagcttcttc gaggtgatct tgtcgcccat cgcttcgatg gccctgactg
   722821 gcggaccgat gaaggttacg ccctctttct ccagagcctc ggcgaaggcg gaattttcag
   722881 aaaggaagcc gtagccagga tgcaccgcat cggcgccggt cttgcggatt gcctcaagaa
   722941 tcctgtctat gacgatatag gactggtttg agggtgaggg gccgatagga acggcctcgt
   723001 ccgccatgcg cacatgcatc gcgtcgcggt ccgcatccga gtagacggcg acggtcggga
   723061 tgtcgagaga cttcgctgtg cggatgacgc ggcaggcgat ttcaccacga ttggcaatga
   723121 ggattttctt gaacatgttt tccatggggt tctcccgtca aagcgggatc gtgtcgtgct
   723181 tgcgccaccg ggtctccagc tgcttgctgc gcagagacgc gaaggcacgg gcaatgcgac
   723241 ggcgggagga atgcggcatg atcacctcgt cgatgaagcc gcgctctgcg gcaacgaagg
   723301 gattggcgaa gcgctcctcg tattccttcg tccgcgcggc gatcttctcc ttgtcgccga
   723361 gctcggaccg gtagaggatt tcggtcgcgc ccttggctcc catcacggcg atctcggccg
   723421 tcggccaggc gtaattcaca tcggcgccga tgtgtttgga cgccatgacg tcataggcgc
   723481 cgccataggc cttgcgggtg atcagggtca ccatggggac cgtcgcctga ctgtaggcga
   723541 aaagcagctt ggcgccgtgc ttgatgacgc cgccatattc ctgggcggtg ccgggaagga
   723601 agccgggcac atcgacaagc gtcaggatcg ggatggagaa cgcgtcgcag aagcggacga
   723661 agcgtgcggc cttgcgcgag gagtcgatat cgaggcagcc ggcgagcacc aacggctggt
   723721 tggccacgac gccgaccgtc tggccctcga tgcggatgaa gcccgttatg atgttccggg
   723781 cgaagcttgc ctgcagttcg aagaagtcgc cctcgtcggc aatggcgatg atcagttcct
   723841 tcatgtcgta gggcttggcg gcactgtccg ggatcaggct gtcgagccgc atctcgatgc
   723901 gccccggatc gtcatggaag ggccggaccg gaggcttctc gcgattgttg agcggcagga
   723961 agtcgaacaa cagccggacg tgctcgagcg cctctatgtc gttttcatag gcaccgtcgg
   724021 cgacggagga tttcgtcgta tgcgtgcggg caccgccgag ttcctccgcg gtgacgatct
   724081 cattggtgac cgtcttcacg acgtccggcc cggtcacgaa catgtaggaa ctgtcgcgca
   724141 ccatgaagat gaaatccgtc atcgccggcg aatagacggc tccgccagca caggggccca
   724201 tgatcaccga gatttgcgga atgacgcccg agacctctgc attgcggcgg aagacctcgg
   724261 catagccggc aagcgacgaa acgccttcct ggatgcgggc gccgccggaa tcgttgaggc
   724321 cgatgaccgg cgcaccgttc cttgcagcca tatccatgat cttgcagatc ttctgcgcat
   724381 gcgtctccga aagcgagccc ccgaggacgg tgaagtcctg gctgaagaca tagacctgtc
   724441 ggccgttgat cgtgccccag ccggtgacga cgccgtcgcc ggcgatcttc tggctaccca
   724501 tgtcgaaatc gacgcaacga tgcgtcacat acatgtcgta ttcttcgaag gagccctcgt
   724561 cgagaagcac gtcgatgcgc tcgcgtgccg tcagcttgcc tttgccgtgc tgcgcggcga
   724621 tgcgacgttc gccgccgccg acccttgcct cggcccgccg ggcttccacc tgttcaagta
   724681 tcgcgcgcat cgcgctcctc cctgtcttgc cgatagtgca gaggctttcc ggccttcgca
   724741 atagcgccga aggcctgatg gaaaaacgtc cgatgatgtg caaatgtgaa acatagaatg
   724801 ttgcgaagcg caaattgcaa aattgcgaac acgagttgaa tcatggcgat tggcaagctg
   724861 tatatcggcc gcaaggtcag ggatctgagg gatggcaagc ggctgacgca ggcgcagttc
   724921 gccgagcgga tcggcatatc cacgagctat ctcaatcaga tcgagaacaa ccagcgtccg
   724981 gtgtcggcgt cggtgctgct ggcgctcgcc gaaaaattcc agatcgatat cgccgaactt
   725041 tcctcgggcg agagcgaccg gcttctctca gcgctatcgg aggcgctgag cgatcccctg
   725101 ttcgagacct attcgccgag cctgcaggag ctgaagctcg ttgtccagaa tgcgccgggt
   725161 cttgcccatg cgctgatctc ctgccaccag gcctatcggc gcaacagcga gcagctcgcc
   725221 agcatcgacg atacgatcgg ccgcggcgct tctttcgtcg agacgacgcc ttatgaagag
   725281 gttcgggact tcttccactt cgtcgacaat tacatccacg aaatcgatac gcttgccgag
   725341 actttggccg acgagctggg ccttggcgat ggcgacaacc atgcggccct tgcggcctat
   725401 ctcgaagagc gccacgggat acgtgtcgtg cgcggggcag ccggcgacga ggcgatccgc
   725461 cgtttcgatc cgcgcgcccg cgtgctcacg ctcaatcctt acgccccggc ggcgacacgc
   725521 gactttcagc tggcattgca gatcgcccag acacgcgccc gcgaggagat cgatcgggtg
   725581 gcggggagcg ccggcttccg caccgaggag gcctatgaga tctgtcgaat cgggctgcag
   725641 aactattttg ccggcgcgct gatcctgccc tatcagccgt tcctcaaggc cgcgcgcgaa
   725701 ttgcgtcacg acgtggaact ccttgcagcc cgcttcggtg cctcgctgga gcaggtttgt
   725761 caccggcttt cgacgctgca gcggcccggg cagaagggca tccccatctt tttcgcgcgg
   725821 atcgaccgcg ccggcaacat caccaagcgc cacagcgccg ccaagctgca attcgcccgt
   725881 ttcggcgcgg cctgtccgtt atggaacgtg caccaggcct tcgagacgcc cggccgcatc
   725941 atccgccagc tcgcggagac gccggacggc gtgcgttatc tctgtctcgc gacccagatc
   726001 accaagggcg gcggcggcta ccgcgccgcc catccccgtt atgccttggc gctcggctgt
   726061 gaaatctcct acgccgatgc cttcgtctat gcggacgaca tggacctcgg caaccgcgcc
   726121 gcctacgatc cgatcggtat ttcctgtcgc atctgcgagc gcacgagatg cgcgagccgc
   726181 gcggtgccgc cgctcaagcg caagctgatc gtcgaccatg acatgcgcgg cgctctgccg
   726241 tatcgtctga gtgagagctg acctccctct ctgttcgttt ttgaacagat gctgtgagaa
   726301 tttacgcctg tgcctgtacg gcgtttgttg taactagagc gggataagga aaagtgggtg
   726361 cggttttccg cccgcatccc gctctaattt attggaatcg atcgcgatct ttttagggtc
   726421 gacacgacct aaaaacatcg tgatcgaggc gctacaccat cactatgcgg gtcagggagg
   726481 acatgcatat ggattttcgc ctgtcggagg agcaggaggc catccgcacg atggcgttcg
   726541 attttgcgcg ggacgagatc gcgccccacg ccgtcgactg ggaccagcag aagcactttc
   726601 ctgtggagac cttgcgcgcg gcggccgcgc tggggatggc cggcatctat gtgcgcgacg
   726661 atgtcggcgg aacgggtctt acccgtctcg acgcggccat gatcatcgag gcgctcgcga
   726721 ccggctgccc cgcgatcgcc tccttcgttt cgatccacaa tatgtgcgcc ggcatgatcg
   726781 accgctacgg cacggacgag cagcgccagc gcctgcttcc gccgcttctc accatggacg
   726841 tcctggcgag ttattgcctg acggagcccg ggtccggctc ggacgcggcc gcgctcaaga
   726901 caaaggcggt gcgcgagggt gaggcctatc tgcttaccgg ccagaaacag ttcatttccg
   726961 gcgcaggagt gtccgggctc tatatcgtca tggcgcgcac tggcgaggag gggccgaagg
   727021 gtatctccgc cttcgtcgtc gagaaggacg ctccggggct gaccttcggc gccaatgaga
   727081 agaagatggg ctggcatgcc cagccgacgc gggcggtgat gctcgacagt gttcgcgttc
   727141 ccgtcgagaa tcgcctgggg gccgagggcg agggcttcag gatcgccatg gccggcctcg
   727201 acggcggaag gctcaacatc gccgccgcct cgctcggcgg cgcgcaatcc gctttcgaca
   727261 aggcgctcgc ctacgtccag gggcgccgcg cattcggcaa ggcgatcggc gaattccagg
   727321 cgttgcagtt ccgccttgcc gacatggcta cggatctgga aatcgcccgg acattcctct
   727381 ggcgggcggc ctccgccctc gatgcggcgg acccggaggc cacgaagctt tgcgccatgg
   727441 ccaaacgttt tgtcacggat cgctgctttg ctgtcgccaa tgacgcactg caattgcatg
   727501 gcggctacgg ctatctcgcc gactacggcg tcgagaagat cgtcagggat ctgcgggtgc
   727561 accagatact cgaaggcaca aacgaaatca tgcggctgat cgtgtcgagg gcgatcacgg
   727621 gacggaaata ggaaggattt tcgatggaga tgcaggcaac gtttccggag gtcatcgtcg
   727681 agcgccaggg cgctatcggc agactgcggc tcaaccgtcc gcgggcactg aacagcctca
   727741 atcgcgcgat gatccgcgcg atcgctgcgg cgctgacaga attcgagcgt gatccggcga
   727801 ttgccgcagt gcttgtcacc ggagaaggtg aaaggggcct ctgcgccggc ggcgacatcc
   727861 gcatgatcta cgaaagcggc cgcgaacggc ctgaggaagg tgcgcagttc tggcgcgagg
   727921 agttcatcgt caacagccga atttccgcct attccaagcc ctatgtcgcg atcatggacg
   727981 gcatcgtcat gggcggcggc gtcggcgttt cctcccatgg cagccaccgc atcgtgaccg
   728041 agagaacgcg gttcgccatg ccggaaacgg ggatcggcta tttcaccgat gtcggcgcga
   728101 cctggctcct gccgcgcgcg ccgggcgaat tcggtaccta tctcggcctc accggccggg
   728161 atatcggggc ggcggcggtc atccatgcgc ggcttggcga cagcttcgtg ccctcggaga
   728221 ggattgatga actcgtcgcc attctcgcct cgctgcccgc ttcggccaag gccgaggatg
   728281 tttcggcggc gatccgcacc gtctcggccc aggcgccggc ttcggcgctg ctcgatcatc
   728341 agcccgtcat cgaccgctgc ttcgcttccg atacggttga ggaaatcctc ggcgcgctgg
   728401 aaaatgaggg cacggacttt tcgcgcgaga cgctggactt gctgaaaacc cgatcggcga
   728461 tcagcctcaa gctgacgctc gctttgctgc gggccgggcg cgccagcgcc agcctggacg
   728521 aatgcctgga gcgggaatat gccgcgaccc tcggtatgct ttccaatccg gatttctacg
   728581 agggtgtcag ggcagcagtg atcgacaagg atcgcaatcc caaatggtcc gtcgggcttt
   728641 cgcaggtgac cccggcggtg ctcgaccgct tccagaggaa cgaaggcgcc ccgctttttg
   728701 ccgggcaggc gtaggcggcg acgcatcgat catatcaggc agacacaagt tgaagaggag
   728761 aggcctatga cgaagatcgc ctttatcgga cttggcaata tgggcgggcc gatggctgcc
   728821 aatctggtga aggcgggcca cgcggtcacc ggcttcgacc ttttggaagc ctcgcgcaac
   728881 gccgccgcca agagcggggt ttcggtggcg ggttcgatcg cccaggccgt gcgcgagatg
   728941 gagtgcgtca tcaccatgct gccggcgagc gcgcatgttc tttacgtctg ggacgagctg
   729001 ctcggcttcg tcgaccccgg cacccttctg atcgacagtt cgaccatcga tgtcgagagt
   729061 gcgcgcaagg tgcatgggct tgccgaaaag gccaattgcc cctcgctcga cgcacctgtt
   729121 tccggcggca ccgccggggc ggcgggcgct acattgacgt tcatggtcgg ggggagcgac
   729181 ggcgctttct cgcgcggcaa gcacctgctc gaagcaatgg gcaagaagat cgtccattgc
   729241 ggcgatgccg gtgccggcca ggctgcgaag atctgcaaca acatgatcct cggcgtctcc
   729301 atggcggcgg tctgcgaagc cttcgtgctt gccgagcggc tcggcctatc gcatcaggcg
   729361 ctcttcgacg tggcctcgac ctcgtccggc cagtgctggt cgctgacgac ctactgcccg
   729421 gtgccggggc cggttccgac atcgccggcc aacagcggct acaagcccgg tttcgccgca
   729481 agcctgatgc tgaaggacct gaaactctca cagcaggccg ccagcgccag cggtgcggcg
   729541 acccccatgg gcgcgcaggc gatgcagctc tacagcctct tcgagaagct cggccacggg
   729601 tcagaggatt tctcggcgct gatccatctg ctcaggggga acgaggaagg gaaggccgag
   729661 tagaccaccc accgcgttac ccgcttacat ctgtaccgtc atcccgccgt cgactgtgag
   729721 cgtggtgccg ttgacgaaac tcgcagcggg cgaggcaagg aacacggcgg caggcgcgat
   729781 ctcttccggc cgaccccacc gcttcagcgg aatgcgcatg tcgacgaaag ccgtgagtgc
   729841 cgggtcggct gcgagatgcg cgttggtttc ggttgcgaac cagccaggcg cgatcgcgtt
   729901 gacggtgaga ttgtcggctc cgagctcgac agcaagtgag cgagttagcg ccgagaggcc
   729961 gcccttcgcc gccgtatagg cgggatcacc ggcccgcgcc gcgaaggcgg caatcgaggt
   730021 cacgaaaatc agtcgtccgg cggccgaacg ccggagatgc ggcagcgcgg cccttgccat
   730081 ggcataggcc gcggtaaggt cggtgttcaa tagcgccgcg aattcgtgcg gctccatcgc
   730141 ttccgtgcca cggcggtcgc gttccccgac cgcatgaagc agaatgtcga gcccgcctgt
   730201 cttctcgacc gctgcggcaa caatcgcatc tgcatcgcgg gttatgtcgc cgggtgcgat
   730261 gccggtctcg atgccatcgc gtgccagccg cgcgcgcgcc tcttcaaggt tttggcgatt
   730321 gcggccgttg atcacggtcc aggcgccggc cctggcaagc gccttggcaa tctcaaggcc
   730381 gagcccacgt ccgccgccgg taaccagagc agttttgccg ttgaggtcga acatcggttt
   730441 ccctcgtcgc ttagtggacc accggctgca aggcgggttt caggcgtagc ttctgagcgt
   730501 tgccgcagat ccatgctgca ggagacccgc cagcgccttg atgagcgcgg agcggaaggg
   730561 agcgctggcc ggaagatccg tgccgaagac gtccgccatc gtcaaaaggg catcgacgat
   730621 gcgatccggc tcgtcaagtc cgcgggcgag ttcggcgatg cggcctgcat gcggatcgcg
   730681 aacgtcgatg gtcccgcccg cctcgtccag gccccgcgca tatcgcatcc aggcagcgac
   730741 tcccagcgcc agccggtcat agccggcccc tgcctgcaac cggtcgcgga tcgtgccgag
   730801 aaggcgctgc ggcaacttct gcgagccgtc catggcgatc tgccaggtgc ggtgacgaag
   730861 cgccggattg cgaaagcgca ggagcagttc ggaccggtag gccggaaggt cgaaacccgg
   730921 cagttccgga agcgtggggc tgacctcttc acgcatcaat ccttcgatca atgcttgcat
   730981 gcccgggagg gccatcgcat ccgccaccgt ctcggcgcct gcgagatagc cgagataggc
   731041 gagcgtcgaa tggcttccgt tcagaagccg gagcttcatg aactcaaagg cggagacgtc
   731101 atcgacgaag agcgcgccgg ccttttccca ggcaggacgg ccgagcggga aatcgtcctc
   731161 tatcacccat tgccggaagg gttcggtcat gatcggccag gcatcttcaa gacccagagc
   731221 ctcggcgacc gcgctccggt cggcatccgt cgttgccgga acgatgcggt cgaccatcgt
   731281 cgatggcgag gccacattgc ggaccaaggc ggcaagggcc ggatcgcgca actccgcgaa
   731341 ctgctcgacg atacgtttca ggacgttgcc gttgccggga agattgtcgc aggacagcag
   731401 cgcgaacggc gcgataccgg cgcggacgcg gcgcgaaatc gcctcgacaa tgaaaccgat
   731461 tgccgagcgc gggcacgccg gattggcgag atcgtgggcg atatccgggt ggttttcgtc
   731521 gagcgtcccg gtcgcgggat tatggcaata gcccttctcg gtgattgtca acgacacgat
   731581 gcgcgtggcc ggatcggcca tgcggcgaag gacggcctcc gggtcttccg gcgcgcataa
   731641 gagctcgacg acgctgccga tcacgctgaa gtcggtcccc gcgccgtcct ttacggcgag
   731701 cgtataaagc ccgtcctgcg gccgaagagc atcgcgcgtg tccgggctgc gcagcgatac
   731761 gccgcagatg ccccaggagg ggtcttctgc aagcagggca tcggtcaagg cggcctgatg
   731821 cgcgcgatga aaggcgccga tgccgagatg gacgatgccg acggcaacag ctccgaggtc
   731881 gtatgcgggg cttttgacgg aggcgggcag gcggtcgagc gtctcttgcg aaaggcgcat
   731941 cagaaggccc gccctttttc ggtatccgct tgttcaattt ctgcagacgg cgccgtcttt
   732001 gcgccacgcg ctgtggcagt ctgcgccata aatcgcctgg taaccaccct cacttggttg
   732061 cggtgtttgg cattcacgcg gcttcctccc tgcgtcgatc ggctgcaaaa ctggtatacc
   732121 agccgccaga ggcgcgtcaa ccgaggtcgc cctgccgcct acccgggcat cgcctactgc
   732181 atgtgtcctt tgatcggatc cgattgaagg acaaaaacat gcagcagatc aaagtgctac
   732241 agcgaccatt gtgcgtctga taagacacac ggcgctgtag gtcatcggca cggcaaggct
   732301 gcagaccggc gtcacgccgc tgcggcggtc actcaaatgc cataaaactg gggaggctca
   732361 cgagggatcg agcacgatct tcgccgcccg ccctggcgcc aactgcgccg attgttcttt
   732421 gccgcggtag tctgcgcttg gggcgggcat catcccaagg acctgcatga gaaggttcgc
   732481 cgcgaccaaa gccgaacagc gaggttcacc gcgatgcatt ccatccgaga ccgtcttccc
   732541 gtctccatca tcatagcgaa ttacaattat gcccggtttc taaaccgtgc gatcgacagc
   732601 gcgctcagtc agaaccatgc gaatgtcgag gtcatcgtcg tcgacgacgc gtcgaccgac
   732661 gggtccgcag atgtgatctc atcctacgga gcgcggatca aagcctgtct gaggaaggcg
   732721 aatggcggtc acgcggccgc gttcaacacc ggcttcgccg aaagtcgagg ggagatcgtt
   732781 ttttttctcg acgccgacga ctacctctat ccgacggcgg tatccgaact gctggcgcgc
   732841 tgggatgacg acacggccca aatgcagttc cggctgcacc tggtagacga ggggcagcgc
   732901 gtgaaggaca tcttcccgcc gctcgaggtt ccgttcgact ccggtgacgt cacgccgcaa
   732961 ctggcgcgcc gcgcccgtta tcagacgacg gtcaccagcg gattggcttt cgcgcgcaag
   733021 gccctggatg tcataatgcc tgttccggaa gtcgagttcc ggcagggcgc cgacggctac
   733081 ctcgtcacgc ttgcaccgct ttacggaaag gtgacgtcgc tcgatgcctg cctcggtgcc
   733141 tatcggatac atgggggcaa tcattcggtc tttgccgaga aactcggaca gagggcgcgc
   733201 tggcgggtgg aacatgattt tcaccggctg caggcgctta cggaacaggc ctcccaagtc
   733261 ggattgtcga tttcgccgaa ggcgaacctg cgcgacccgg tgcatctgga ggagcgcatc
   733321 gcgtcgctct gcgtggacag cgggcgccac ccggtggccg cggattcgag gctcggcctc
   733381 gccgccgccg gtgcggtcgc cagtatgcgt atgaatgtct cgctgcgccg ccgtgcgatg
   733441 ctggcagcct ggttcgtctc cgttgggctt ctgccgccgc gcatggcgca ggcggtactt
   733501 tcgtggaagc tcgtctcatc ttcacggccg gctttcctca tgcggctgtc gagaaccata
   733561 cgccacgcca tgggctagag gtgggttctc ctcggggagc ggtcagctcg cgcggtcgcg
   733621 cactcacatg tgtgacgttt tcgtgtccgc tcagacttca gagcgcgagc gtggccccga
   733681 ttttcgccgg atgcggcggg tcgactccct tgcgcgcaag gtgcaggcga tccgcctgtg
   733741 gacggggggc acgtccatct ttttcatgcg ccgctggagc agctcccagc acgcatggcc
   733801 gagctcgtcc aacggctgct cgatcgtgct gacatagggg cgcaggacgg tcatccagtc
   733861 ggagtcgtcg aagccgagca aagacacgtc ttgcgggaat gcgaggtcca gcgccctgat
   733921 cgcctttgcg gcgcccaagg tcgcgacata ggccgacgcg aagaccgcag tcggccggcc
   733981 ggcccttcgg agttcctgct cgatggcgct gcggcagctc tcgatgctca ggcctccata
   734041 gaccacattc gcatcggaga cgcccgcgtc ctgcatcgcc ttacggtagc cggaaacgcg
   734101 ctcctccatg ttggcgagcc ccggcgcggt cgcgagaaag gtgatgcgct tgtgaccgag
   734161 ctcgatcagg tgccgggctc ccatcagtgt cgcctgttcg ttgtcggccg agaccgtgtc
   734221 gaagccttcg accgcaaagg cacggtcgac cagcaccgta ggaatgccgc tgatggcgga
   734281 gtgcggcgag gtctcgatgg agtccctgct tggcgatatg atcaatccgt cgacctgtcg
   734341 tgaaacaagt gcgcgaatac gttctcgttc ctccgctgcc tcctcgtagc tgctcatgag
   734401 caggatctga aagccggatt tggcagcctt gagttccagt tcgcggacaa gccctgaaaa
   734461 aaacgggttg gtcatgtccg gcacgacgat gccgatggat tttgtccggc cgaaacgcag
   734521 gctcgaagcc agatgattcg gccggtagtc gagttgagca atggcgtcga ggacggcctt
   734581 gcgcaggggt tcggccacga gtttcttgcc cgtgagcaca ttggaaaccg tcccgggcgc
   734641 cacgccggca agcgccgcca cctcccggat cgttgcagcc ttgtttgcgc cgccaaccat
   734701 ttgcagaact cgttacatgc atcgaaacgc ccgatcatat cgatcccggc gccggcttca
   734761 acgatctcct caccggcgtg acggaccagg cgatctacag cgccgtgcgt cttatcagac
   734821 gcacaaaggt cgctgtagca ctttgatctg ctgcatggtt ttgtccttca atcggatccg
   734881 attaaaggac acatgcagta gggagaccgc ggcaggggct tatcaggaca ccgtgaccgg
   734941 tttcgatctc agccggcgca ctgtggccgg gtcggccctt cggcatagct gcggtggcag
   735001 gcccctcatg atgagttccg catcggcgac cgccatcgag ccgagagcat aaaacgcgtc
   735061 gcgcgtgccg ccggtccggt gagcggacag aagcagaccg ggggtcgtgc gcaccgggtc
   735121 atccggtgcg acgggctctt cggggaaaac gtcggtggcc acgcggatgt gcccggaacc
   735181 ggcggcctcg agcatcgccg gaaaatcgac gactgccgcg cggctcatga gcaggaaggc
   735241 ggcgcctttg cgcatcaggg aaaattcgcg cgccccgatg aacccttcat tctcactggt
   735301 aacgctcgca aagacgaaca cgacctgact ctcggacagg agttcgtcga gactggacgg
   735361 aacgcagtcc gcgcgctgga cgatctcttc cggaagccac ggatcgaaaa cgcgaacatg
   735421 attgcggaac gggcggatga gctcgcgcag ctgttgcccg agatcaccga agccgatgat
   735481 gccgaccgga gcgccggcga accgaaaggt ctcctcattg ccagcaaggc cgtactgctc
   735541 ggcgccgaca cggaagtcgc gatctgcctt tgtaatccct cgggcgaggt ccagagccat
   735601 tgccagcgaa gcctcggcta caggcgaggc gaaggcggat gccggggtga tcacccagat
   735661 gccacgctct acgcaggttt gatagtcgat gttcggaagg aagttgcttt cgacattgat
   735721 gattgcctta agttttcgtg cccggtccag acgttccttc ggcatgtctg tctggccaaa
   735781 gatcagcacg gcatcaggga gaagcgcgtc cacctgctcg gccggcatgg gccggtcctc
   735841 ggagatgacg acctcaccaa gccgatgcag cctcgccttt acgctcgggt ccatgatgag
   735901 gtccactgtc cgcggcagcg gatcgacaag gataacgtcg cgactcataa gctcctccta
   735961 atccctgcaa aatcaactaa tgggaaaaac gtttttctgc aatacggatc tgtttgctgc
   736021 attcagagag ccggcgacag ccacccagcc cgcagaagcg cttcgggcct cgatggttcg
   736081 gcgagagctc cctgccagcg ggttcgagtt cttttgggga ctgcgctgac acggcctcca
   736141 ttacatccgg caagaagtgc cggaaggctg ttccgtggca gaacctgtcc tatattcact
   736201 gacgaccacc ttcatcgagc agagccgcgc atccggcgcg aaggccgttg cgataaaccg
   736261 ggagaaagag catgcgcatt gaacccgtct ttctgttcga tctggacggc acactcgtcg
   736321 acagcgtcta ccagcacgtg cttgcctgga aagaggcctt ggacgccgaa gggatcgacc
   736381 tctcggtttg gcgcattcat cgtaagatcg gcatgagcgg cgggctcttc gccgaccagc
   736441 tcctgcgaga aacgaatatg gaaatcagcg cggaacgggt aggtcgcttg cgtcagtacc
   736501 acgccgccgc ctacaagcgg caagccgaca gcatccggcc gctgccaggc gcgcgtgaac
   736561 tcctgacatg gcttaccgat gcgaagatct cctatgcgat cgccacgagc gggcggatgg
   736621 agacggcggc cgtcaatctg gccgcgcttg gtatcgatcc ggcggtcgtg ccggtcgtca
   736681 cccgggatct ggtcaaatat gccaagcctg atccggacct ctttctcgct gccgccgagc
   736741 aactcggcgc accgatcgag acggcggtcg tcgtcgggga cagtatctgg gacatgctgg
   736801 ctgcggtacg ctgccgcgcc ctggccatcg ggttgctgag cggaggctac ggacatgagg
   736861 aattgcggca cgccggcgcc taccgcattt tcgaagaccc ggccgacatg ctgcatcaca
   736921 tagacgaggt tggcgggcgg aggtgaatta cgggcgctgc cggctcagtg cttcgtttcg
   736981 tcgaccaggg cttcttcgtg ataccagcag ccgtcaacgg cagcgcacac gtctgacggt
   737041 gcgacgtccg gcttgcgctg ggcttcggaa cgccgctctt cggccttccg cgaaacggaa
   737101 gccggaaact tcaggatcgt agcagacttg ccgtaaagac ttgtggccat gctctggtct
   737161 cccgtgagtt ctgcgagaaa catagtgcaa ccggacataa attgcacatg ttttacgcca
   737221 gttgctgaaa aatcgttcaa cccgctgccg gaatcacggg catggccttc ggctgccacc
   737281 agcgtggtgc ctccgggtgc tgatttttag gcagcggcgc tcgagcggcg gcttttcagg
   737341 cgaacgactt cctgcccatc acggcaattt cctcggcggg gccggggtaa acgccgcgag
   737401 actaccaata aaatcaacgg cgtgggctct gctgagaacg cgacaaagca cgcgagcgcc
   737461 atcgttgcgc atcacatgct gcgcggtact ttccttcaca aggcgctacg ccagctggaa
   737521 agtggagacg ccccaaagcg agttggcacg tttgatgctt aaggcaaatg gatccctggc
   737581 ggccagacgc atttggcgcc gaagccctgt caggatttgc cgaacctcgc agtacccacg
   737641 ttagagagat tgactgatga ccaagtataa gctcgagtac atctggcttg atggctacac
   737701 gcccgtacca aatctccgcg gaaaaacgca gatcaaggaa ttcgacgcgt ttccgacgct
   737761 cgagcagctt ccgctctggg gctttgacgg cagctctacg ctgcaggccg agggccgcag
   737821 ctccgattgt gtgctgaagc cggttgccgt ctatcccgat ccggtccgca cgaatggcgc
   737881 attggtcatg tgcgaggtga tgatgccgga cggcaagaca ccgcatgcgt cgaatacccg
   737941 ggcaacggtc ctcgatgacg aaggcgcctg gttcggcttc gagcaggaat atttcttcta
   738001 caagaacggc cgcccactgg gcttcccgga gcagggctat ccggcgccgc agggcccata
   738061 ctataccggc gtcggctaca agaatgtcgg cgacgtcgcg cgccagatcg ttgaagagca
   738121 tctcgacatc tgccttgctg cgggcatcaa ccacgaaggc atcaacgccg aagtggccaa
   738181 ggggcaatgg gagttccaga tctttggcaa gggttccaaa aaagctgccg acgaggtctg
   738241 gctggcgcgc tatctcctgc tgcgcctgac ggaaaaatac ggcatcgacg tcgaattcca
   738301 ctgcaagccg ctcggcgaca cggactggaa cggctcgggc atgcacgcga acttctcgac
   738361 ggcctatctg cgtgaagtcg gcggccagga ctatttcgaa gcgctgatgg cagccttcga
   738421 gaagaacctg cacgaccaca tcaacgtcta tggccctgat aaccatttgc gcctgactgg
   738481 caagcacgag acggcgccgt gggataagtt cagctacggc gtggcagatc gcggcgcctc
   738541 tatccgcgtg ccccatagtt tcgtcaacaa tggctatcgc ggctatctcg aagatcgccg
   738601 cccgaactcc cagggcgacc cctaccagat cgcttctatc atcctgaaga cgatctcgag
   738661 cgtgccgacg gcggtcgcca aggtcgcttg atctctctcc cgacttttta tggcgccggc
   738721 tcgattgccg gcgccatttt ttattgtccg atgccacatc cttgctcgcc ggctttctgc
   738781 tggggcacct cggccggcag ttctcggggt tcccctcaaa ttccgtggat tgcgcaattg
   738841 ccggtgtgtt gtaacttacc gtgtacgact ctggagtgcg gactgcacgc cggtttcatc
   738901 agggggtaat ggatgccgga catttcgccg ggccgcacaa gcttcgcggc cagtgacagg
   738961 gcacttcgcc gcttgtcgat attgaatgct catgtcttgc cgggggctcc gtctgcctca
   739021 agcgatcgca ttcggtgcga attcaacaaa ctccttctcg gttcggttgc ctcgattgcg
   739081 ctcttttgca gcctcgactc cgaggctcgg gcggcctgcg tcgaaacgag ccccggcgcc
   739141 tacgactgct cggggacggg ccccggtcca acatttacag ggcagtccgt tacgatcaat
   739201 gccgatccca ccgcgagctt cacgagtgat gtctcgatca ccggacccgg cacgagcacg
   739261 ctcaacaata acggcacgct caccaacagc ctgcgcgcca cggacaacga ccgcttcacg
   739321 ctcaacaatc gcggcctgat cgacgggacg atttttctcg gcggctcggg agcgaacgtt
   739381 attatcaact atgccggggg cgacgttcag aacggcgtca cgagcacggg agattcccac
   739441 gacacagtaa tcaaccgcgg cttttttgcc gggtcgatcg ttctcggcga cggatacgac
   739501 gtgctgggtc tgattgaggg gaccgtccag acatctgtcg atatgggagc gggcgacgac
   739561 cagttcacct ggctggtcgg aaacattgct gcaaccgtcc agatgggcga gggcgacgac
   739621 cgagcggtct tcggaagcct gacgcagcag aatctcagcg ccggcaagag ggtcgacggc
   739681 ggtctgggaa tcgacaccct ggtgtgggag aatacgacca acgacgatgg aggcggttcg
   739741 ggcgatcatc cggaaaacat cgtcaactgg gaggaaatcg agctacgcaa cggctcggaa
   739801 atgaccttca tctacagcac cggcaatctg acgctcggcg attccgcatc cggaaccggg
   739861 acgctctcga tcgacgagac gagcgcggtc agggctggaa attccttcgg ctatggcgtc
   739921 agagcgttcg atccatcgca attggtgacg gtctacaatg ccggcatcat cgatatgacg
   739981 aacgacacgg tgaatgtcgg tgatctcctg cacgacacct tcacggtcta cggcaactat
   740041 gtcggccagc agggtgggct gcagctgcac acggtgctcg aaagcgacga tgcgccctcg
   740101 gacaagctgg tcatcagcgg cacgggcgcg agcgcctctg gcggaacctc gattttgatc
   740161 accaatgtcg gggggcaggg agcgctgacg ctcgccgacg gcatcagggt cgtggatgcc
   740221 actgccggtg caaccactga ggggactgcc ttcacgctgg gcgctcccgt cgcagcaggc
   740281 attttcgagt ataagctcta tcgcggcggt ctgaccgaag atccggacaa cgacgacgac
   740341 tggttcttac gctccggcgg cgtttcgcca ccaccgccgc cgccaccgcc gccaccgccg
   740401 ccaccgccac cgccgccgcc gtcaccaccg ccgccgccgc cgccgtcacc accgccgccg
   740461 ccgccaccgc cgccgccacc gccgccgccg ccgccgccgc cgccgccacc gccgggaccg
   740521 tcgccgatca cgccgtcggt acggccggaa atacccggct acatcgtgaa gccagcgctt
   740581 atgcagaaga tgggcgtggc agccattggc acctttcacg agcggcaggg cgaccaattc
   740641 ctgctgaaca gcaacgggta tctccccgga gcgtggggac ggctgttcgg cgagtcgttc
   740701 gatcaaagct ggtcgtccaa gatcagcagg ttcgaattcg aggtcagtcc gtcctcctcg
   740761 ggagagctgt ggggacttca ggccggtcag gacttgatcg gagccctgca cgacgacgga
   740821 agccaggatc gcgtcggcgt gttctttgct tataccggca cgtcgggatc gaacggaggc
   740881 aatacgctcg ggaggctgca ggtcgaatcg ggctcgatcg atctccatgc caactcgatc
   740941 ggcgcctatt ggacgcatat cggagcggac ggctggtatg tggacagtat agggatgtac
   741001 tcatggctgg atgggggttc gaactccgat cggggcatcg gggtcgacac atccgggaac
   741061 tcgaccgccc tttcgatcga ggcgggttat ccgttcaggt tcgataacgg atgggtgctc
   741121 gagccacagg gccagcttat ctggcaacat gtagacctgg atgacgcgaa tgaccgcttc
   741181 accggcatcg actatgagtc cttcggaaca tggacgggcc gtctcggtgt gaggctcgaa
   741241 gcaaacacga cgatgaacga tgttccagtc cagcccttcg ccagcgtcaa cttgtggcat
   741301 gatttcgatc aggactataa ggtctcgttc aaccgggttc ctgtcgtaac agaactggaa
   741361 cagacgttgc tcgaattgaa tgttgggttt tcggcccaga tgagcgagac ggtcagcgtc
   741421 tatggcggcc tgcagtttgc gacaggcctc gacgatgacg acaacagggg ctacggcggc
   741481 aatataggct tgcgcatcaa atggtagata ttccgcatga agagattgac cgcctatgtg
   741541 atcgacggac atgaactgac catccgtccc gctccactgg agcgtgattg gatgaacagg
   741601 acaaaccagc gcttcgccta ccgttgcctg cccttgaaca ttgcgaatgc gcatgggtgg
   741661 gaaattctga accaggccgg cttttccacg gtgtgggatg gaggcgaacg cgagaatgcc
   741721 gttcgcattg aaccggatcc gggcacgcat gcgcccgcag tcagccactt cggaagcgga
   741781 acgctgacct ttcatattcc atgcctgttc aagacggacg gcggaaccga cctgttcgtg
   741841 acggggccgt tgaacaggcc gaaggacggc atcgcggcac tgacgggtat catcgagacc
   741901 gattggtcgc cctacacctt caccatgaat tggcagttca cccgggcggg gcactggatc
   741961 cggttcgaag cgggcgagcc gatctgtcac atctttccgg tctcgcgcgg cgggcttgag
   742021 gccgttacac ccgaaatgcg caagctgtcg gagaatccgg agctcgaagg cgaatacaag
   742081 gcctggtcgg acagccggaa cagtttcaac gaggggctga gcgacccgaa ctccgatgcg
   742141 gtccgggaga agtggcagaa gtcttatttt cgcggggtgt gcccgtccgg gcgcaacggg
   742201 ccggcggatc accgcagccg attgagacta aagcccttcg gctgacgatc gttagggaag
   742261 gccgttcccc aaacgaagga ggcgtcggcc atggcggcgc gatcctgtcc acttcatttt
   742321 tacggcttgg cggctacagc gccgtgcgtc ttatcagacg cacaaaggtc gctgtagcac
   742381 tttgatctgc tgcatggttt tgtcctccaa tcggatccga ctaaaggaag catgcagtat
   742441 gccacccgcc atgtcagccg tggcggttgc ccgggaagct tgccggatcg atgccgaggg
   742501 tacggagatc ctgtgccttc ggccggcggt gcccttcaac ggcagcggct gcagcggttg
   742561 cggcaccgag cacggcgaag gcgcggccga taaagcccat gcggttcttg ctggtcatct
   742621 cttgctcgct ttcgttttct attcgatgag caaaagatgg tcccggcagg gttgttttgc
   742681 aatgcacaaa acctcaggcc agccatgcag agacggcagg cccgatggcc gcagccgacc
   742741 ggacctcctc tggcgaggga ttgatcagtc ttcgctggcg gcgagctggg caagcatttc
   742801 accgcgtcca cgggctctga ggataagcgg cacgatcaag gcaagcgcgg caatcaccag
   742861 gagcactgcc gcgagcggcg aggtgaagag cacggtaacg tccccctggc tgatcgaaag
   742921 cgccctgcgg agctgctgct cagcaagcgg ccccagaatg aggccgacga cgaccggcgc
   742981 gatcggatag ccgaagatgc gcatgacgta accgagcagg ccgaaggcga gcagcattcc
   743041 gagctcgaag acggaagggt tggcgccgat ggtgccgagc gtcgcgaaaa gcaggatgcc
   743101 cgcatagagc cacggcttcg ggatcgtcaa gagcttcacc cagaggccga tcaacggcag
   743161 gttgaggacg agcagcatga aattcgcgat aagaaggctg gcgataaggc cccagacaag
   743221 ctgcggattg gtggcgaaaa gcagcggccc cggctgcagc ccgtattgct ggaacccggc
   743281 cagcatgatc gcagcggtag cggtcgtcgg caggccgagc gtcaggagcg gcacaagcgt
   743341 acccgccgcg gatgcgttgt tggcggcctc gggacctgca acgccttcga tggcgccgtt
   743401 gccgaattct tccgggtgct tggtcaggcg cttctcggct gcataggaga gaaaggtgcc
   743461 gatctcggcg ccgccggccg gcatggcgcc gataggaaag ccgataaagg tgccgcgcag
   743521 ccacggcttc caggagcgcc cccaatccgc ggcattcatc cagaccgagc ccttgaccgc
   743581 ttccaccttg tccggaccgc ggtcgccttg cgcagcgatg aacagcgtct cgccgatggc
   743641 gaacatggcg acagcgagcg tggtcacctc gatgccgtcg aggaggtcgg gtactccgaa
   743701 ggaaaggcgc gcctggccgg tcagctggtc gatgccgata caggccaggg tcaagccgac
   743761 gaaaagcgag gtgagcccac gcagcgtcga gtcaccgaag gcggacgaga cggtcacgaa
   743821 ggcgagcacc atcaacgcga aatattcgcg tggtccgaag acgagcgcca gcttgacgat
   743881 atagggcgca atgaaggcga ggccgagggt ggcgatgagg ccggcgacga aggatccgat
   743941 cgccgcagtg gcgagcgctg ggccaccgcg gccggcgcgc gccatcttgt tgccctcgag
   744001 cgcggtgacg atcgaagcgc tttcgccggg cgtgttgagc aggatcgacg tggtcgagcc
   744061 cccatacatg ccgccataat agataccggc gaacatgatg agcgacccgg ccggatcgag
   744121 ctgataggtg accggcagaa gcagtgcgac ggtcaatgcg gggccgatgc cgggcagcac
   744181 gccgacggcg gtaccaagcg ttacgccgat cagggcgtag agcaggttca tcggctgggc
   744241 agcgaccagc agcccctgca acaggaaatc gaaagtaccc atggtcgtcg gcctctttag
   744301 aagaacaggc gttcaagcgg ccctgcgggc agcgacaatt gcaggagctt ggcgaatacc
   744361 gcccatacgg cgaagctgaa cgcaatgccg accggcacgg tcagccacag tctgcgtttg
   744421 ccgaagccgc gggccgtgag ggcgaagaga atgccggtgg cgatcgagaa accgagcgtg
   744481 ttcaagagca gcatctgcgc cgcaaggccg gcgacgatcc agacgaccgg gcctgcctgt
   744541 tggtgctcac gttcggggaa gtcgccacgc caggcctcta tcgccgtcca gaccgcaagc
   744601 gcgatgagac agcaggcgat cgcatagggc acggtcatag gcccgacctg agagtagccg
   744661 gcaagtccgg tgaggcgcga cacgtcccag aagatgaccg cggcaattgc cgccaggacg
   744721 acggcgatga tcagcgccgc cctgtcgggg cggcgcgttt cgacggaagg gttgttcccc
   744781 ttgttcattt gaccagcccg atgtccttca ggacggtttc cgtggcggag atgtccttgg
   744841 cgagctgttc ctcgaaagca tctcctgcga gataggtatc ctgccaaccc ttggtcttca
   744901 gcacttcctg ccagccagca gatttcgcaa gcttctcgac atcggcttcg acggcggtct
   744961 tctgttcgtc ggtaaggccc ggggcggcgg cgaccatgcg ccagttctcg acaacgacat
   745021 cgacgccgga ttccttcagc gtcggggcgt ctatgccctc gatgcgctcg gcgctggaca
   745081 cggcgagaag acgcagcgtg ccggccttca cctgggattc gaattcgccg tagccggaga
   745141 tgccggcggt cacctggctg ccgagaatcg cagcaagcgc ctcgccgccg ccggaatagg
   745201 cgatgtagtt gatcttggtc gggtcgaccc cggctgcctt ggcgataagg ccaaccgcga
   745261 tgtggtcggt cccgccggcc gagccgcctg cccaggaaac cgcgcccgga tcctttttca
   745321 acgcttcgac gaggtctttc atcgtctgga tctcggaaga ggcgggaacg acgatcgcct
   745381 catattcgcc cgtgagccgc gcgatcggcg tcacgtcctt gaggctgacc ggagaattgt
   745441 tggtgaggat ggcgccgacc atgacgtaac cgccgacgag gagcgcatta gggttgccct
   745501 tctgctggct ggcgaactgg gcaaggccga tcgtaccacc ggcgcccgga acgttttgaa
   745561 cctgcacgtt gccggaaata ccttcctgct gcatgacggt ctgcatggag cgggcggtct
   745621 gatcccagcc gccgccggga ttggccggtg cgataatcgt gtagtcggcg gcatagaccg
   745681 gcaaagcaag ggcgccggcg agaatggatg cgagaaagac gtgtttcaag gtcggtcctc
   745741 cgtgaggcgc gcttcgtcac gcgcacgttg attatcgttc gcgaagggga gaagcggctg
   745801 gccggcatca gcgacgacct tagaccggat tggtgattcc tcccgatacg ctgccggcgt
   745861 tccgcctcca cggttcgccg acgaccttaa gcaacataga aagctgacat taacctgaca
   745921 tcaagtcagc ttctcgtaaa tgactcgttt gtgtgctcgt ctgttcactg cgatcgcagc
   745981 gtctcgttcc agcgcgcgat cagccgtgcc cgcttgacct gatcgagata gaccatgagg
   746041 ccggggctga ccggcacggg cttcaactgg cctccgagca tttctcgcat ggtatttgcc
   746101 gtgttctcgc cggccacttc ggggctgacg gccggaatct gcagctcgcg cgccatgatc
   746161 gtctggccct ccttcgacat gaagaattga agatatcgcc ggccgagttc cggctcggct
   746221 gcagcctgcg gcaccaatcc gatgcgcgac atcacgaccg tgtagtcttt cgggagcacg
   746281 atgccgacat ccggatgtcg cgatgcccag tcggccgcat aggaaccgag gatgttgtag
   746341 ccgagcacga accgcccgtc cgaaatcctc tccaggatcg cctgactggt cgaatagagt
   746401 ttcacgcccg ctgcgcccat cgtccggatc accgtccaga tgtcgccgaa ctgctcctgg
   746461 tcgcgtgaca tgaagaggaa gccgacgccg gagcgttcga tgtcgtaggt gccgatgcgg
   746521 ccgaagacgg cattgccctt gcgcttgagg taatcgacga attcggcgcg tgtcgccggc
   746581 ggccgctcat tgcggaagct cggcttgtgg tagacgaaga cggccggctc gaaagtcagc
   746641 gcgtatgccg tgttgcgcca gttcgcccat gccggccagc ggccggtcat gggcaggtcg
   746701 ctgcgctgtg catagccgtc attgctgagc ttgacctgca ggtccatggc ggaggaaaag
   746761 gcgaaatcgg cggttttctc tccggcatcg gtttccctga cgatcctgtc gtagatctcg
   746821 ccggtcagca tgtcgtcata tcggacagcg acgtccggat tggcactttg aaagcccttg
   746881 atcatcggtc tcgccaaggg ctcgtcgagt gaggaataga cggtcaggac tggtgcggcg
   746941 gggtcaccgg agggagccgg gaaaaacgcc ggcgcagcct tggccagcgc ggccgacaga
   747001 atcaaaaaac caagagaaat caagaaccgc atgaaaccac aatgcctgag agtgctgccg
   747061 ttcacaagca agctcccaac cgatagaatg ttgccgggga gaggcgatat tgcgtatctt
   747121 gctggttgaa gacaatcggg ctctggcgga gggcctttca acgcttctgc gcggcagcgg
   747181 ctatgccgtc gatgtcgtga gcgacggcgc atcggcgcat gcggtcgctg cggcagagag
   747241 tttcgacctc gtgatcctgg atttgaacct gccggaaatg gacgggctgg acgtgctgcg
   747301 cgccatgcgg gcacggcaaa atcgtgcggc ggttctcatc ctgacggctc gcggtgcgcc
   747361 ggaagaacgg gtcaagggtc tggatctcgg tgccgacgat tatctgatca agccgttcga
   747421 catcggcgaa ttcgaggcac gcgtgcgggt tctcctgcgg cggcaggcgg gattgcgggc
   747481 ttccgtcgtc agttacggcg aggtctcgtt ggatttgaca acgcggagtt tctcctcggc
   747541 gggaatgccg atcgagatcc cggcgcgtga gctcggcctc ctggagctcc tgttcatgcg
   747601 cgccggcaag gtcgtcgcca aggatgcgat cgtgcaatcg ttgaccgacc tcgacgacga
   747661 tctgagcccg aatgcaatcg agcaatatgt gagccgcctg cgcaagcggc tgtcgcccta
   747721 cggcctcacc gtccggaccg ctcgggggat cggctattat ctcgacaaga cggccgatcc
   747781 cgaatgaacg tctccgggat aaggaaaggc gtctattcgc tccggcgcag gctgctcggc
   747841 tggctcttga tctcgacagc cgtgatcggc gtcgtcgcgc tggcggacac atacagggag
   747901 gccgtcaaga cggcgaacgc cgtctcggac cgggtgctgg ccggatcggc cctggcgatc
   747961 gccgagcgtg tggtcgtcgc cgaggacggt tcgctggagg tcgacattcc ctatgtcgcg
   748021 ctcgaaatgc tgacatctgc ggcacaggat cgggtgtttt accgggtgga tggcccgccc
   748081 ggcgcgttca tcaccgggta ccagacgctg ccgtcactct ccgagaatac cggacagtcg
   748141 acgagcttcg ccgatgctgt gtttcgcggc gagcccattc gtgtcgcaga gcttcgccgc
   748201 tccgcctcaa cgggcgtcaa ctccgttccc ttcgtcgtca ccgtcgccga aacgacgatc
   748261 gcccgccgcc ggctcgcgcg gacgatcctc atcagatcgg ccttgcgtct ggcgctgatg
   748321 atcgccgggg cggcaataat cgtctgggtc gccgtcacct tctcgctgag gccgctctac
   748381 cggcttgggg atgcgatcgc cgagcgcagt cccgacgacc tccacccaat ccgcgaacgt
   748441 gtgcccaacg aagttcaggg gcttgtcgat accgtcaact ccttcatggt acgcctgcaa
   748501 tcggccctcg acgcgctgcg gcacttcacc ggcaatgcca gccatcagct cagaaccccg
   748561 ctcgcgatca ttcgcacgca gcttgcgttg gcgcagcgcg cgaccacgat cgaggaaacc
   748621 cgggcggccg cgatgagggc ggacgaagcc gtcgccgatg ccgagcgcat tctcgcgcag
   748681 ctcctgctga tggcgaagat cgatgccgcg ggccggaacg aggcgcgggg actggagcgg
   748741 gtcgacctcg ccgggctcgc ccgcaccgtc acggcagatc acgtgcctgc ggcgggcgaa
   748801 gccggcattg acctcggctt tgccggagaa ggcgagcact gggtccgcgc cgagcccctg
   748861 cttgtcggcg aactcctgaa gaacctgatc ggcaatgctc tgctctatgc cggtcgcggg
   748921 gcggaggtga ccgtgcgcgt cgggagctgc gaccactcgg tcctgctgga agtggaagac
   748981 aatggcccgg gcattccgcc tgacatgcgc gaggcggcgc tcaagcgttt ccggcgcggc
   749041 ggcgaagagg cgcccggtac ggggctcggc ctgccgatcg tcgaggaaat agccgagctc
   749101 tacggcggga gaatgcggct cgaggagggc gagggtggtc ttgggttgaa ggtggaagtg
   749161 atgtttccag cggggtgagg gggtggcccc ttgcgccgcg tctagaatgt agaatcaaac
   749221 ggcctgcccc ggaaacccgc ggcaggccgt atcttcacta tctccgacgc ccgatcagaa
   749281 cggcgagtcg gggaaataga agtccttcgc gttttccttg gttaccagcg tcgcatcgat
   749341 cgtgtagacg ccgcgaaccg gaacctggcc gtagaagttg gcaaccgtca tttcgagcgc
   749401 cgtgccgacc attgccggcg ggtagagcac gtcgacgggg atcatcttgt cgccgtccat
   749461 gaccttcttg atcatgtcct tcgagcctgc gcccgccacg acatactgga tatccgtgcg
   749521 cttggcctga tcgatcgcct gcagcacgcc gacggccatg tcgtcatcct gacaccatac
   749581 gacatcgatc tgcgggtatt tggtcaggta atcctgcatg accttgaagg cgtcgtcgcg
   749641 gttccagttg ccgtactggc ggtcgaggat ctcgacgttg gagccctcga tgcccttatc
   749701 gaatccgtct tgacgctgct ggtcgatcgg gatcggcagg ccgcgaatga ccaccacctt
   749761 cgcatccgga gtggttgcct tgatgtattc gccggccacc tggccgagcg cggggttatt
   749821 gccggcgaca tagaggtcgc gcacgctgct gtcgttgacc gagggcgcgc ggtcgaccag
   749881 cgccacgaat ttgccgttgc tcttgacctc cttgatcgca ttgaccagcg gatcggggtc
   749941 ggtcggcagt atcacgaggg cgtcgatccc ctgtgtttcg aggtcctgca cggcgtttgc
   750001 ctggctcgcc ggatcgggcg aagtcttgac aatgacgttg aggcccggat gctgctccat
   750061 gagcagcttt gcgacgcgct cggcatggaa tacgacaccg gcggtccagc catggtcggc
   750121 cgccgggatc gacacaccga tcgtgacctt cttttcctgc gcatgggctg cgcccgtcag
   750181 ggccatcatg gcgatggccg caatgcccat taatcccttt cgcatgcttt gttcctccca
   750241 atggttcaag gtcttggctt aatgtggccg gctcttttga ggtccgcccg cttcacgatt
   750301 tacgcaccag cgaacgctgg acgagcatcg cgatgatgat gatcgcacct tgcatcgcgc
   750361 cgatcaggta ttcgctgatg aaattcgaca ggagcatgat gttgccgacc aattcgagaa
   750421 tgaatgcacc gcagatcgtg ccccagacgc ggcccgcgcc gcccttgagc gccgtgccgc
   750481 cgacgacgac cgcggtgatc gcctgcagct cccagagaat gcccgtggtc gccgaggtcg
   750541 agccgaggcg cggcacgtag agcagcaccg ctacggcgac gcagagcccc tggattacga
   750601 aggcgatggt gcgcacgcgg ttgacggcga tgccggaata gcgggcgacg tcgctgttgg
   750661 agccaacggc gaccacgtgt ctgccgtaac gggtgcggta gagaatgaaa gcggcaacgg
   750721 cggtaacggc gaggatgatc gcgatcggaa cagggacgcc gaatatgctg ccgaaatagg
   750781 cggggcggta gagttcctgt atttccggct cgcgcagcgt gatcgcgccc ccttgcgaga
   750841 gccaggtcgt aaggccgcga tagatgccca tcgtgccgag cgtcgcaatg aaaggctcga
   750901 tcctgccgac ggtggtgatc agtccgtttg cgaggccgca ggcgccgccg acggcaaccg
   750961 cgaagacgat tgcagccgta agcatcaacg ccggatcggc gatcacaccg gaattcatga
   751021 aaatgatcat aaggctcgca acgaaggcca ccatcgaacc gacggaaagg tcgaggtcgc
   751081 ctgccgaaat gacgaaggtg gcccccacgg cgataatggc gatgaaggcg ctgcgggtgg
   751141 cgacgtttgc aaggttgttg aggctgatga agttggggtt gaccagcgcg cccacgatca
   751201 acagcagggc aagcgcggca aatggcgcga cagcccttag atccacgtcc cgccaggtgc
   751261 ggcggtgcgt tgtgctttgg atgctttcct cgttcacgct catgttcgga tcaacctccc
   751321 gccccggagt ccggggaaat ccctattcct gtgtctgctt tatgccgtga tcgacgcggt
   751381 caggcagcag ccattttctt cagtccggcc gcgtagcgca tgatttcttg ctcggagatc
   751441 tcgtctcctt cgagcatgcc tacgatacgc ccctcgcgca tcaccgcgac cctggtgcaa
   751501 agcccgatga cctcaggcat ttcggatgag acgacgatga tcgagctacc gtcccgcgcc
   751561 agcgccgaga tgaaatgata gatctgctgc ttggtgccga catcgatgcc gcgcgtcggc
   751621 tcgtcgatga tgatgatgtc cggttccgtc tccatcacct tggcgagcag cagcttctgc
   751681 tgattgccgc cggacatgcg cctggcaacc acattgccgt cgcgcacacg gatatcgaat
   751741 ctgcggcggg ccctttcgag tgcggcggcc tcgctcgccg ggctgagata gccgatgcgg
   751801 gcatggcggc cgagtgactg cagcgtcagg tttgccgtca tgccggaatt gagcagcaga
   751861 cccttcgcct tgcggtcctt cgtcatatag gcaaggccgc accggttggc cgcgtggacg
   751921 tcgccggagg gtacgctttc tccacgaatc gccacctcgc ccgagaggcg gtgcctgagg
   751981 cccgcgacgg cctccatgag ttcggtccgg ccggaaccga tcattcccga gaatccgagt
   752041 atttcgcctc tgcggacctc aaaactggcg tccttgacgt aatcggtcga gagagcatcc
   752101 acacgcagga cgacctcttc gtcgacatca ggttcgtttt tggcgggata gaggctggac
   752161 atttcgcggc cgaccatgag ctgtgcgatc gactcgccgt cgagcatgga tgtcggggcg
   752221 gtcttcaccc attgaccatc tcgcagcacc gtgacccggt ccgtcagttc gatgacctcg
   752281 tcgagcttat gcgacacgaa gacgaagctc gtgccacggt cacgcagctt gcgtacctgg
   752341 cggaaaagga aacttgtctc ttcgcgcgag agaaccgccg tcggctcgtc catgaagacg
   752401 atccgcgcgt cgcgactgat ggctttggcg atctcgacca tctgtttttc ggcgatggac
   752461 aggctcccga tcagggcgtt cgcgtccacg ttacaaccga gaagatcgag aacccggcgc
   752521 gtctcggcgc gcatatattt ccgatcgagc atgccgaatc gcgtcacctc tcggcccagg
   752581 aacaggcttt cggcaaccgt cagatgctcg gcaagattga attcctggtg aatgatgacg
   752641 atgcccagag cttcggccgc gccattcgca ggaaaagtca cccgctcgcc gtcgagaagg
   752701 acctcgccgg aggatggctg ctcgaagccc gagagaatct tgacgagtgt agacttgccg
   752761 gccccgttct cgcccatcag ggcgtggatt tcgccggcgc gaagctcgaa attgacgctg
   752821 aagagtacct gcacgccgct gaacgacttg ctgatgcgac gcgcttccag cacgacgcgt
   752881 gctgcgtcga ccgcttccgg atccatcgtt tccccccttt gcggctcccg cccgacaatg
   752941 gagacgatgt aaacctttac acccgctatg taaaggttta catcgggaca tacacaggaa
   753001 tttattcggc ggcctttgac gttgcctgcg gtgtgtgtag tgtcccgccg tgtacagcgc
   753061 cgcgccccta aagaggcgca aaggccgccg tagcagtttg aatcgccgca tgttttaccc
   753121 tagcgccgag gctttaaggg agacatgcgg tagggagacg caaggcagag cgcagtgtcg
   753181 gattccaccc ccgcaaccat cgaggacgtc gccaggatcg ccgaggtgtc gatcgcaacg
   753241 gtatcgcggg caatccatac tccggaaaag gttgcaaaat cgacgcggct gaaggtcaac
   753301 caggcgatcg cgatcaccgg ttacaccacg aatgccatgg cccgcagcct gcgcctcggc
   753361 cgctccaaca tgatcctggt cgttgccccc gatattggcg atccgaactt ttcaagcatc
   753421 ctggtcggcc tcgaaaacga ggcgcggtcg cacggctatg gcgtgctgat cggccacacc
   753481 cagaacgacg ctcagcgcgc cgtcgaatat ctcaaatttc tgaattccaa tcaggcggcc
   753541 ggcctgattc tctttaccgg catcctgccc ttcggccacg aaacaattgc cgcgcggttg
   753601 ccgccgagcg tcggcatctt cgaacccgta ttcaacggcg gcatacccta tgttggggtg
   753661 gacgacgagg agggggctcg caaggtggtc gacctcctcc ttgccgaagg tcatcgcaag
   753721 atcgccttca tcggcgactc gcggacccgg cttgcctata agcggcgtcg cgccggctac
   753781 gatgcgggtc tcaattccgc aggggttccc gcggaactcc ggctggtcca ggagggcgac
   753841 ggcacgctcg agagcggcag ggccgctgtc gagcgtcttt tcgtgcgcga tacgctgccc
   753901 accgcattca tgtgcgtcaa cgaccagaca gcactcgggg tgatgatcgg gctgaaggca
   753961 cgtggctacg acataccgcg ggatttctcg gtcaccggct tcgacgacgt accgcaggcg
   754021 acgttcatga cgccggccct gaccacaatc cgccagcctc gcacgctgat cggaaaacac
   754081 gccatggcgc ttctgctgga gctgctttcc aacgggctcc cggcggagat ggaaatcctg
   754141 ctgagacccg atctggtggt gcgcaattcc gtctcgacac cgtctccgcg atggcgggaa
   754201 cgataggttc agcctgccgc gtcagcggat attcgaggct tcaaaacgac cgcgtgcggg
   754261 aactgaagag ggaagctgct ccgcgggtct gaaccccaag catcgcattc catagctgga
   754321 gcatgaagcc gggttcggcg cgtttcgcaa gctggcgctg cgagggcatg ataattctcc
   754381 gatggttttg catgtccgtc acatagtcta tctgtgatgc aagagccaga ccgtagtcat
   754441 aggggctgca ttgcaggacg agcatatgtc atttcgcgag aatatctctg ccagacacgc
   754501 tgacagataa gaaaatgccg ggataaactt cttcatcccg gccagtcgct ctgctgggag
   754561 gagcagtctt ttttacgctt ttttccggct tttctgacga tacacgtcga cgaccaccgc
   754621 agcgacgatg atgatgcctt tgacgatttc ctggtagtag gcgtcgaccc tgaggaaagt
   754681 gaagccggac gtcatcacgc cgaggatcac cgtgccgatc accgtcccgg tgatgcggcc
   754741 gacgcccccg gtcagcgaag tgccgccgat gacggtcgcg gcgatcgcat cgagctcata
   754801 catgaccccc attccggcct gcgccgtctg ggcgcgcgcg gcggtgacca cgccagccag
   754861 accggcgagc atgccggcga tcgcatagac cttcaccaga tgcgcttcga cattgatgcc
   754921 ggagactcgc gcggcctgca cattggcgcc gatcgcatag gtaaacttgc cgtaacgggt
   754981 gtagcgcaac gcgatgtgaa atataagggc gacgacgagg aagacgataa ccggccagat
   755041 gcctgtgccg atgaagttga actgctcggt gaggccggag accggctggc ccttcgtgta
   755101 ccacttggag acgccgcgag ccgataccat cattcccagc gtggcaatga agggcgggat
   755161 cttggttctg gcgatcagct gaccattaat gaagccggcg agaaggccga tcccgacgcc
   755221 gaggccgatc ggtatgatag ccggcaggtc cgtcagcgac ggataaagcg ccctcggcca
   755281 tgtggaggcc tgggcgacgc ttgccgagat catcgccgtc atgccgacga ccgagcccga
   755341 cgaaaggtcg atgccgccag tgatgatgac ctgggtgact cccacggcga taatgccgat
   755401 aaccgagacc tgcagaatca tgatcgtcag acgctgcgta ttcatcagaa agctctggcc
   755461 gacgaagagc cagccaagaa tctcgtagac gagcgcgata ccgatcagca ccagaaagat
   755521 gctgagttcg ggcggcatgc gccgtcttga gcgaacgagg ggcgaattcg tgccctgcgc
   755581 tgcgacattg ctattcattt tctttcctcc ctgcgctcgg cagcgcgccg agatcggttc
   755641 caaaagtcag agcggaaggc gggcgaaaac cgcacgcgct ttcccttatc ccgctctagc
   755701 gcgccgcaag ctccatcact ttgatttgag tggcgtccgc cctgtccaga atgccggtca
   755761 cacggccctc gtgcatcacc atgatgcggt cgctcatgcc gagcacctcc ggcatttccg
   755821 atgagatcat gatgaccgcg acgccattgc gggcgagctc ggtcaccagg cggtggatct
   755881 cggccttcgc gccgacatcg atgccgcgtg tcggctcgtc cagtatcagg atgcgcggat
   755941 tggtgagcag ccagcgtccg atcagcacct tctgctggtt gccgcctgac agattttcga
   756001 tgcgttcgta gagattgggg gttttgaccc ggagcttgcg gctcatgtcc tcgcaagccg
   756061 cagcaacctc cttttcgctg acaaagccgc ccctgacgaa tttgtcctgg agaacggcga
   756121 tctgcatgtt ttcgagaatg tttaaaatga gcaggcagcc ggtgtccttg cgatcctcgg
   756181 tgagaaacgc cattcggtgg cggatcgccg tattggcgct gtcgatcacc accttgttgc
   756241 catcgatcgc gatcgtgccc gaactcgccg gcgtgacgcc gaagagcgtc tcggccacgt
   756301 tggagcggcc ggagccgacg aggccggcga cgcctagaat ctcgcccgcg cgcacatcga
   756361 aggtgacgtc gtggaagacg ccgttgagcg tcaggttctt caccgacagc accacatcgc
   756421 cgattggcac gtcttccttc gggaacatct gggtgatttc acgaccgacc atcatccgaa
   756481 tgatgtcgtc tcgcgtgacc tcgttggaga ggtgggtacc gatatatttc ccgtctcgga
   756541 aaaccgagaa ctcgtcggcg atctcgaaca gttcgttcat cttgtgggtg atgtagacga
   756601 tgccgatgcc ctgcgagcgc aagtcgcgaa tgatctcgaa aagatgggcg acctcgcgct
   756661 cggtcagtgc cgaggtgggc tcgtccatga tgaggacgtc ggactcgtag gaaacagcct
   756721 ttgcgatctc gaccatctgg cggttggcga cggagaggtg acggacctcg atctccggat
   756781 cgagatcgat cttgagacgc tcgaagagct ttgccgtcat gcggcgcatc tcgccgtggt
   756841 cgaccaggcc gaagcggttc ttcggttccc ggcgaatcca gatgttctcg gcgacggtca
   756901 tgaacggcat caggttcaat tcctggtgga tcatggcgat gccgttctcg agcgcatcga
   756961 gcggcgattt caaccggata ccggcgcccc tgagcttcac ctcgccccgg tcgggatggt
   757021 agatccccgc tagaattttc atcagagtcg acttgccggc tccgttttcg cccatcagcg
   757081 catgcacggt gccgcgctta agcttgaact ccacatcgtc gagcgcaacc acgccgggaa
   757141 attccttgcg aatgccctcc gccgtcagaa ggtattcgga ttggggaacg gcgccactgg
   757201 cgcgcacggc ggccattgtc gtgggactga gtgtcattct cgttgcctcc catgttccgg
   757261 tttcagccgg accccacgcg gtaggcggaa catgccttcc agtcggcttt tgtgggcctg
   757321 gacggtagga cgcgcgggca tcgagggagc gcggcaacgc cacgccccac gattttcact
   757381 gaagcccggg gcgcggattc accgcgcccc gggcatcgaa aatcagttct tcgcctgata
   757441 ctgctccagg ttttccttcg tgacgagctc gaaaggaatg tagaccttct tctcgacagg
   757501 ctcgcccttg gcgagcttca gagcggcatc gaccgaaccc ttgccctgcc cagcggcatt
   757561 ctggaaaacc gtcacgtcaa ggtcgccggc ggccatggct gcgagcgcgt cctgcgttgc
   757621 gtcaatgccg ccgatcacga cggagtccat agagcgtccg gccgccttca acgcctgaat
   757681 ggcgccgatc gccatctcgt cgttgttgga gatcacggcg tcgaattcga ggccggcgga
   757741 gagccagttc gtcatgagat ccgccccttg cgtgcgcgac cagttcgcgg tctgctcctc
   757801 gacaatctcg atgcccttgc attcgtcggt tgcgacgaca tcgtgaatgt ccttggtgcg
   757861 catgcgcgcg gcctggttgg agagctcgcc catcatgacc acggctttgc ccttgccgcc
   757921 cagcatctta cagatttcct tggtctgcag cgtgccggat tcctgttcat tcgacgcaac
   757981 gaaagcctgc ttttccggaa gcgtgtccac gttcaccggc tcacggttga cgtagacgag
   758041 cggaatgccc gcgtcggccg cgatcttcga catgacggtc gtcgcgtctg tgtcgaccgg
   758101 attgacgatg atggcgtcga caccggcggc aatgaaattc tggatctgac tctgctgctt
   758161 ggagacgtcg ttctgagcgt cttcgacctg cagctcgacg ccgtcaaggg ttttggcata
   758221 gtcctgcatg ccgctgcgca gcacggtcag aaagttgtca tcgaagagcg ccatcgacac
   758281 cccgattgtc tctgcatgcg ctgccgtcga catcagcacg gccaaggcgg tgcccgcgaa
   758341 aaatttcttc attttcttct cctccacttg gtgccggcga caccttcttc agccggaaac
   758401 gtgatcgtct cgcgatcgcg tccaaacctg gaatggaagc ggcactcccg ttgcgcgctt
   758461 ccgtcaaaac ggaacaaaca aaccgatgtt tctatattac ggaatatgta ttccatttta
   758521 tcttgatccc gtcaagagtg cccgggtctt cacggccggt tttccgctct ttcgatcgaa
   758581 ggtggcgatc agctccgcac ccggaggtag ttcatgctct cgcgaagggc gtttgccggg
   758641 tcggcgagtt catgcacgga tggagcgaag ggctcgaaag agagggggcc ggcatagcct
   758701 tctgcccgca atcggcgaat ctgaccttcg ttgtcgagcc tgtctcccgt gccgatgaga
   758761 acgcgatccg ggtcgcgcat atccgcgacc gcgagattgc cgtcggcaac gccggaaata
   758821 tgaacgagac ctgtcatatc ggctaaaaac cgatcttctc ctgacaggtg atggtgaaac
   758881 gtatcatgca ccagccggaa ggttccatca ccggaaattt cccggatcgc atcggccgct
   758941 tccgccttcg aacggagcga acagacctcg aacccgagcg gctccacgag tccggctatg
   759001 gcggcagtgt cgagcatcgg cttcagcgcg ctcagcgctt gccgcagatt tgcctgccgg
   759061 acgcggtctt ccttgccgct gccgtcattg acgggcacga gcaccagagc ttttgcgccg
   759121 caattgcgcg cgtaagagat gagttcgtgc gcctcgtctg cccgtgtctc gttccattcg
   759181 ttgaaccgct gcaaggcgtt gatcgagatg atcgttaatc catatttctc cgcaagggct
   759241 ttcacctgct gcgagttcgt cccatcaaga atggcgttgc cggcaatgtc gttgcggatt
   759301 tcgaccattg agatgccgag cgacgcggcc agcgcgaaga acgcgtcgag gggcagggcc
   759361 ggagcggcca tatggttgag ggcgaagggg agggcggcag tcatgacggt gtctcctcgg
   759421 ggacggcgct gaaacgcgga acgtttgttc cattttcact tcgcacacat tggctattcc
   759481 gcgagatcca gtcaaagccg cagatcggcg gcaatgttgc attcctgcaa gattacattt
   759541 caagcctgat ggaattctgt catgccggcc cgacaagcgg ccctcgccgc cccttcactc
   759601 cagaccgttc gacttcgcga tgaaatccga cagcatcggc acgtagtcct cgccgcggcc
   759661 tgcgccgacg gcctgggcaa aggaattccg gacggccgcc ccgatcggat tggcaatgcc
   759721 ggccgcattc gcatagccgg cgagatagct catgtccttg aaggcgttgc ggatcgcgaa
   759781 cttgtgggcg ttcgggtcgc gttccagaac ccagcggaag aaggtctggt agaaggggca
   759841 atccatccgg cctccgcgga tgacgctgtc gaaaacctcg ggcgtgagcc ctgccttgcg
   759901 cccgagcatg agcgcttcgg aataaagagc agcgtagccc atcgagacaa agttgttgag
   759961 cagcttcatg gtgtgaccgg agccagtcgg cccggtgtgg atgatgcggc ccgcaaagca
   760021 ttcgagtacg ggccagatgc gctggacgtc gttttcggca ccgccgacca tcacgtcgag
   760081 cgtgcccgcg gccgcatctg ccggggtccg gctaagcggc gcatcgatga gcgtgaggcc
   760141 gctttcggcg acatcggccg ccagcttcgt cgtgacggaa gggtcggatg tcgagcagtc
   760201 gataatggtc accggcctgc cggcgctggc gatgccgtcg ggacctccca tgacggagag
   760261 aacttccggc gagccggtga cgcaaaggac gatgatgtca cagtgttccg ccatctcacg
   760321 cggtgacttc gcctctttgg cgccttcggc gacaagcgcc tcgaccggcg cgcggttgcg
   760381 atgcgccata acgaaaagcg gccagccctt tttcagaata ttggccgcca tgccctggcc
   760441 catcaggccg agtccgatga agcctatgtt cgatctcgtc attggtctgc tcctctggat
   760501 cacgatgatt tatgaaaaac ggctcctgtc agaatttccg gctcacgaag ggcgagcgcg
   760561 ccaatccgaa gcgccagggg tgctccacgg ccttggtgat gccgacccgc gggccggtga
   760621 caacaggcgg cttcgtggcg ggcagggtga ggcggaatgg atcccgcccg agcggcaagc
   760681 catcctgctc cctgttgatc gccagcgcct ggccgacacg ccccggaccg gaacacaaaa
   760741 gcctgtcttc acgaacgccc cttctcgccc gcatcgtctc gatgccccat ttcggttcga
   760801 tcgcacggat caataccgcg cttcctggca ggcagacgaa gttcaggcac cagtgcagac
   760861 cgtaggagag gtagatatag gcatgcgccg gcggaccaaa catcgcacga ttgcgcgccg
   760921 tggtaccggc gaaactgtgc gaggccgcgt cgtcggggag ataggcttcc gtttcgacga
   760981 tgacgccgcc gacaccggag acagtgaaat cggacccgat gagatcggcc gccacttcca
   761041 cggcgctgcg cgcaaaaaat tcgacatccg agttcaagcg atacaccggt ctgatgagat
   761101 atcgtctcag tctattcaag agatccggcg agcgccacgc gggaatgaga gaagtaagac
   761161 cgtctttttt gccatcccct acggaaagcg ggttgaattc aagccccggg cgcacgattc
   761221 tccatgaagg aactcgaagc gctgcagcga tccggcgtgc cgcatagggc atacggcgct
   761281 ggaggagagc gaaaccatgc accactatca tatcttcgaa accgcgagcg gttgctgcgg
   761341 tatcgcctgg agcgatgccg gcatcatccg tttccagttg ccgacgcgaa gcgcggagtc
   761401 caccgagcgg ttgctcctgc ggcgattgca gggcggagtg ccgcatgagc cgccgccgcg
   761461 ggtcgccgaa gcaatcgtcg cggtgaaggc ctatttcgag ggcagaaaga cggatttctc
   761521 cggcttcgaa ctcgatctcg aggggcagga cgccttcttc aggcgtgtct accgggccgc
   761581 tcgaaaaatt ccgtggggca gcacgaccac ctacggcgcg cttgcgaagg agctcggcgc
   761641 aggaccggag gttgcccggg atgtcgggca ggcgatggca aaaaatccgg tggcgctgat
   761701 catcccgtgc catagggtgc tcgcggccgg cggcaagatc ggcggcttct cggcgccggg
   761761 cggctcatcc accaagctca gaatgctcga aatggaaggc gtcgctgtcg ccccacccga
   761821 gcctgcgcag caatctctgg ggttttgaca tgacgatcac gaagccgggc gaggcggata
   761881 tcgcattgca gtctccaaca gagccaccct cgaacttgcc cgacggcagc gaggggatat
   761941 ggccggcgcg gcggcgccgg atcatcgact ggctcgtcat cgagacgcgg ggcgaacgct
   762001 tcatcgacaa catcttcgtg gagctgtgca acaggctggt ggaggcggga gttccggttg
   762061 cccgtgccac cctccatttc aggattcacc acccgcaatg gctcggtgct cggatactgt
   762121 ggcgaaaggg actgtcggag gcagagctcg atacctacgc ctatggcgtc gaagattcga
   762181 tcgaatatct gaacagtcca ttgcgcgaat tcaacgaggg ggcggaggaa gtgcgggggc
   762241 atctcgacga tccgccagcc tctggtaagg catacccgct ctacgacgaa ctgcgcgcag
   762301 aaggattgac cgattacctc atctggccgc tttaccatac gctcggcaaa cgccacgcga
   762361 tcacctttgc gagcgaccga ccaggcggct tcgggcccga tgacctgatc tttttgaagg
   762421 atattctgcc tgccctggcg ctcgtcagcg aaatccgcct gaagaaccgc ttcgcccgca
   762481 cgctcctcga aacctatgtc gggccgcatg caagcgagca gatccttgcc ggagcgacca
   762541 cgcgcggcag cggggtgacg gtcggcgccg caattttgat ctgcgatctg cgcgatttca
   762601 caaaactgtc ggacctctgg ccgcgggacg acgtcatcga gcttctgaac ggatatttcg
   762661 acgctatgtc ggaaccgata gagcggcacg gcggagagat actgaaattc atgggcgacg
   762721 ggctgctggc gatcttcccg ctcagcaacc cctgtgcctg cagtcagctt ctcggagcca
   762781 tcgatgaggc gcaggccgct cttgccgttc tcaacgagga gaatctgcgc aagggccacg
   762841 atccgctcgg ctacggtata ggcgttcatg tcggcgatgt gatgtacggc aatatcggtt
   762901 cgcgcaggcg gctcgatttc acggtgatcg gaccggccgt taacatcgcc tcgcgcctcg
   762961 aaaccctcac aaaggagttg aagcgtccgg tcctgctgtc gaaagccttc gtcgagaagg
   763021 cgggctgtgc aggacagctg gaaaatctgg gctcatatgt cttgcgggga cttgatgagc
   763081 cggtcgacgt ttttgctttt tcgggcagac gataggtcac gatgtttagg tcggctcgac
   763141 ctgaaacatg aacgtgatcg attccaaaga gtttgagacg caggatgcgg gcggaaaacc
   763201 gcgcacacct ttcctcatcc cgctgggtac gtcatcggct tgccagtctc cttcttcccg
   763261 cgtgcggagc gaatgagact ggcggagacc gtacgttcac ttcatcgtat aaacatcgat
   763321 ggtgaaatac ttgtcgttga tcttcttgta cgttccgtcg gtgcggatct ggtcaagcgc
   763381 tttgttcagc ttctctcgca gttcgttatc ctcctgacgg acagcaatgc caacgccgtc
   763441 gccaacgaac ttcttgtcgg tgatcggctc tccgataagc tcgcagcaac ccttgccgtc
   763501 gtcgttcttg gtaacccaat cgagtagcgg cagcatgtcg cccacctgca ggtcgagccg
   763561 cccgttgacc atatcgagat tggcttcgtc ctgagtaggg tagagtttga tctcggcatc
   763621 gggatagacg gcagcgatgt aatcggcctg agtcgtgcct gactgagctc cgatcacctt
   763681 gcccttgagc gcttcgttgc tgaagtctgt gatgccggcg cccttcggcg ccgcatgcgt
   763741 catcgctgcg aggtagtagg gatcggtgaa agccacctgc ttcttacggt cctcggtgat
   763801 gaacatcgac gcgatgatca tgtcgtattt gctggcaagc aggccgggga tgatcccgtc
   763861 ccaatcctga gcgaccacct cgcattcgat cttcatgcgc tcgcaaagcg cgaggccgat
   763921 ctccacgtcg aagccgccga tcttgccggt ggaatcgacg aagttgaagg gtggataggc
   763981 accctcggtt ccgatcctca gtttctccgc agccgttgcg gaggaggtca gtgcacaagc
   764041 ggcgagcgca agcgccagaa taaggcttcg catgttcatt cccctcaatt ggcgccattg
   764101 accggcgctt ccggggaaac tctaaagcag atttcctata agcgaaatcg ataggcgcga
   764161 taacggatat tctttgcgtt aatcctacgg ccagcgaagg atggagaact cagcctttca
   764221 gccgcccctg cctcttcagc tgctgttcgc ggaaaaagat gaagaggccc gaggcgacga
   764281 taaggccggc gccgagtacc atcgaaagcc gcggcgtatc gccgaagatc agccatccga
   764341 agaagattgc ccagaaaagg agcgtgtatt gcagcggggc taccgtcgcg gcgtcggcga
   764401 gcttcagcgc ccggttgaca agcacgtggg cgaccattgc gacgacgcca aggagacaga
   764461 gcagcgccgt gtcgagcggc ttgaggggtg tccagtcgaa gggcgcccat acgaggccgg
   764521 ccaccgcggc gccggcaatc tgccaaaagg cgagggtcgt atcaggagtg ccgcgcagcg
   764581 accgcccgga aatcatcatg aaggcgaagg ccatgctgcc aaggatcgaa atgacggccg
   764641 gcagtgtgaa agcctgcgac gacggttcga gtgcgacgac gacgccgacg aagcctatgg
   764701 cgatcgctgt ccagcgccgc cagccgaccg gttccttgag gaccagcggc gaaatggccg
   764761 cgacatagat cggcgcagcc agccaatagg tcatgacatc tgcgagcggc aggtagacga
   764821 cggcgaaata gaaggcgatc acttccgcgg tcgaggcgac cacgcgggca agctgaaggc
   764881 cgggccgctc cagggtgaag agctttttcg ggccgctcac ccatagaaac ggcgcgagca
   764941 ggaggaccgc tgcgatgctg cggatcagca ccacctgacc gaccgagtag gtggctacca
   765001 gccactttcc catgacgtcg tttaccgaaa acatgagcat gccgaggagc atgacgatca
   765061 cgccggcgcg ggcggttcca ttttcatgcg aaagtttgcc ggggacactg tcgacggcca
   765121 tcggttcgat tccttcaaag cgggaccgcg tctccgcggg aacgttctcg gccagccatt
   765181 cgcatattcg ggcagagcaa tccatgccgc actgcttatc aattcatcac ctttgcgaat
   765241 gatagcgatc tggaatgcga gggctgagcg acgggtcacc tgcgtcaggc gctgcggacc
   765301 agacgcatgt cggggttgag gagctcgctg taaagctctg catagcgggc ggcactgcgg
   765361 tgccaggagc aatcggtttt catgccttgc cggcgcagcc cctcccagac gcgtcgcagt
   765421 cggtagagcc tcagggcgcg gcgcagtgcg aggcgcagac cttgcttgtc tatgggcgta
   765481 aactgaatgc cggttgcgac atgggcgtga agcgcggcat cgttcgcatc gatgattgtt
   765541 tctgacaatc cgcccgtgcg agagacgatg ggcacgcagc cgtagcgcag cgcatagagt
   765601 tgcgtgaggc cgcagggctc gaagcgggac ggaacgagca tggcatcggc accggcatga
   765661 attctgtggg cgaggcgctc gtcataaccg atgctgaccc caacgttctg cggataccgt
   765721 cgcatgagat ccatgaacgc ggcctccagc gcctcgtcgc cctgtccatg gacgatcagg
   765781 gtgccgccat tcctgacgat ctcgtccgcg gttgccgcga gaaggtccat gcccttctgc
   765841 catgtcaatc ggttgacgct ggcgaagacc ggtccgcacg tgttcggcag cccgaactgc
   765901 cggagcagca cctgccggtt gggtaggcgg cgcagcggta cgcgcgtcga atagtgatgc
   765961 tcgatgtagg gatccgagga tggatcccag acctccaggt ctatcccgtt gacgatgccg
   766021 acgacgtcga catgccgctc gttcatcacg ccctcgaggc ccatgccgaa agccggcgac
   766081 atgacttccc gtgcataagt agggctgacc acggtgatcg catccgcggc ctgcagtccg
   766141 cccttaagga aaccgatgtc gccgtaatat tcgacgccat cgatagaata ggcttcggcc
   766201 ggaagcccca gctcggggaa gtagtaggcc gggaattgcc cctggaacgc aaggttgtgc
   766261 acggtgagga cacggggaac ggagtcgtcg ccggcgtact tcaaatagag gaggctcatt
   766321 gcggcatgcc agtcatgcgc gtggatcaca tcggggcgcc agttcgttac gaggccgcgt
   766381 gcaatttgcg atccgaccag ggaaaaggcg gcgaagcgtt tccagttgtc cgcatattcc
   766441 cggccgtgcg tgtcggtgta gagaggtcct tgcctgttgt agaaaccagg agcatcgagc
   766501 acgaacagat cgagtccctg cgctcgcccg gcgaggaggg tggcgcgttc gccgaacagg
   766561 ttgtcgaact cggtgatcgc agacgcctcg ctgagcgcac gaaccacgcc gggatagccg
   766621 ggaacgaagc tgcgcgtatg gataccgtga gcctggagcg ccttgggaag cgatccagct
   766681 acatctgcaa ggccgccagt ctttgcgagt ggaaaaattt cggccgtcac agacagtatt
   766741 tgcatcgctc atgttccgga gagagtgcgt cgggtgcgac cggccccatt caccgccgat
   766801 gcgccttcat caacacggtc acgagcctca aagttccggc cgcggaatga aatttgtctg
   766861 aagacaagcg ccgcgtgcgc ggcgggattt gctcctgtgc cgtgcgctcg ccgcacggat
   766921 acatccgttc tgcgccaacg catccaagcg catccgcgcc ggtcggaacg ttcccgaaag
   766981 cctggagttt ccttaccgga gggcaaggaa caggtcatcg aagccaacgg tgttccattg
   767041 cggcactcca tgctggttct tcttgtctgc ctcgcttcgg cgaggcctct ttcgcaacac
   767101 cgcttcggcc gccctcggga acacatgcgg cgacctttgg ttctgctatt tgggagaggg
   767161 cacacaatta tcgcagggaa agttagcggc ggctttcccc cccgaaatag cggcgagaca
   767221 aagttaaagg gtttcccgcg atttggagat aagcgacatt ctcgaagagc gccgctcact
   767281 tgcttgtaca tggaaggagc aactgatgac cttcagtctg atcagtcccg tattcgccga
   767341 cggccagcct ataccgcaga aatacactcg ttttggcgaa aaccttttcc cgccgttgaa
   767401 atggacgggt acgccggacg gaacgcagag cttcgcattg attatcgagg atccggatgc
   767461 ggtaagcggg ctgtttcgcc attgcgggat catcaacatt ccaggccatt ggaccgaact
   767521 tccaaaagcc gtcgataccg ggcctgaacg cgggatcaag ttcatcaaga acgatttcgg
   767581 aaatgcccgt tacgatgggc cgcagccgcc cgtcggaacg ggcgtccacc ggtatcgctt
   767641 caggcttgcc gcgctcgata tcgccaatct ctcgattccg gaagatgtgg gtgccgcgga
   767701 ggcgtgggag agagcctgca agcacctcat cggcgaagcg gagattgtcg gcacctatgg
   767761 aagctagatt ggcataggac tagattggca taggataagt gcgtgcgcgg ccgatgacat
   767821 ctcgacacca tgaaaatagc tgacgtgacg gggctgtatc ttcgacgccc aaatggcaca
   767881 gtattgggct ccgcccgtga acgggatcaa acttcagtgt cattcgttga tattgtggga
   767941 attgaggcgt cggatgacat acgaagataa cagattcccg attgttggca tcggcgcgtc
   768001 ggccggtggt attcctgcaa tgcaggggtt cttcaagggt cttccggtca attccaacat
   768061 ggccttcgtg atcgtgacgc atctcagccc cgagcatgag agccaacttc acgaggtggt
   768121 cgcgcgctac acagacttgc cggtgttggt ggcggaggat gggatggcgg cccagccaaa
   768181 tcatgtctat gtcatgccgc agaatgccat cctctcgatc gcaggcgggc acttgcgtct
   768241 gcgcaagccc gacgccgcca cgcgggagcg caagccgatc gatatctttc tgagcacgct
   768301 ggcggaagat caaggcgagc aggcggtcgg tatcattctt tccggcggcg acagcgatgg
   768361 aacgctgggg gcgaaggcga tcaaggagca tggagggctg acactcgcgc aggcgagcga
   768421 cgggtcaggt ccgcgtaacc cggacatgcc gcaaagcgca atctccagcg gcgtgatcga
   768481 cctggcggtt acagccgaag agatgggcga gaagcttatc gcctatgcca acggtttcat
   768541 ggctgcccaa gacgttgcga cagaggagac gcccgacgcc cgggaagctc gctcggagat
   768601 ctatggactt ctccgcaggc attcgggaca tgatttctca gggtataaat caaaaacgtt
   768661 tctacgccgc gtaagaagac gcatgcagat tcttcaggtt cgagcgctgc cggattactt
   768721 gaagctgctc aggcgcgacc cctcagaggt gacgaacctc ttccgcgacc tattgatcaa
   768781 cgtcaccaat ttcttccgcg accaggatgc gttcaaggca cttgagcaac tggtgatacc
   768841 gcgcctgttc gaaggccgaa aagcgggcga gcccgtgcgt gtatgggttc caggctgcgc
   768901 gacgggggaa gaagtctatt cccttggcat cctcatgcgc gaacgcatgg agaagctggc
   768961 ggacatgccg cgggttcaga ttttcgccac agacattgat gaatccgctc tcggtgtcgc
   769021 ccgggccggc cgttaccctg aagcgctgct gcaaggcctg tcacctgagc gcatagcaag
   769081 acacttcaat tgcgacggcg ccagcttcgt gatcagcagt gatgtgcgcg agctctgcat
   769141 cttctccccg catagcgtta cgcgcgatcc gccgttctcg cgcatggatc tggtatcctg
   769201 ccgcaatctg ctgatctatc tggatcaaga gacgcagaaa cgcgtcatct ccacattcca
   769261 ttatgcgctg aagccgggtg gctatctttt tctcgggacg tccgagagta tcggtcagca
   769321 cggggagcat ttctcgacca ttgacaagaa gaatcgcatt ttccaggcgc gggggcatga
   769381 tgcagtgccc cgtgttccag ccctcgttgg tcctcccaaa acggtgaaca ctgccgatgg
   769441 ccgtatccac ggtctcagga tcggcaccta tccgctgcgg caggtggtcg aagcgcatgt
   769501 tctcgagcgc tttgcccccg cgcatgtcgt cgtcaacgcc gacggcgagg cggtctacta
   769561 ctccgctcgc acgggaaaat acctcgaagt tccccagggc gccccgagcc ggcagattct
   769621 tacgactgca agacggggcc tgcggctcga cttgcgggcg gcgctgcgcg aggccgcctc
   769681 ggcacgaaaa gttgtggtac gcgaaaatgc tttgctggag gacgacgacg atcgggtgca
   769741 acgggttaat ctaaccgtcg agccattggc ggacggcgcc ggtggcgagc ctctttatct
   769801 ggtcgtgttc gatcccatcg ggcctctaca aagccgggcg gaggccgagc attccggata
   769861 tgacgcggat acggcggcta tcctggagag tgagcttcgc gagacgcgcg agcgactgca
   769921 atccaccatc gaagaatacg agacggctct tgaagagctc aagtcctctc acgaagagct
   769981 tgtttccgtc aacgaggagg cgcagtcaac caatgaggag ctggaagcct ccaaggagga
   770041 aatgcagtcg ctcaacgagg aactgagcac gatcaatgcg gaactgaccg caaaggtcga
   770101 ggaactggac cgtgcgaaca gcgacctgaa gaacctgttc gagagcatgc agatcgcaac
   770161 ggtgtttctc gaccgcaacc tcgttatccg caatttcaca ccggctgcct cttcgttctt
   770221 caacatccgg ccgtccgacg tggggcggcc ccttaccgag ctttcaagca agctcgacta
   770281 tccggaactc aaggaacaga tcgcttcggt cttcaagacc ggagaagccg tggaacacca
   770341 tcttgcccgc gatcagaacg gaaagcactt tcttgtacgc ctgatcccct atcgcgacga
   770401 cgcagcacgc gtcgatggtg tcgtggtcac gcttgtcgat gtgacgaaga tggccgaggc
   770461 cgaggcgcac cagcagatgc tggtctcgga actcaatcac cgggtcaaga acatgcttgc
   770521 agtggtgatc agcatcgcca atcatagcat gcagaccgcc cggtcaccga acgagttcaa
   770581 tcaggcgctg atcggccgtc tgcaggcgat ggggcgggct tatggactgt tgaccgagac
   770641 gcactggacc gctgctcccg tcgatcacct catcaggcag gaaatcgaag ccttcggcac
   770701 aggtcgcttc gaagtgaacg ggcctgacat ccacctcgaa cctcaacagg ggctttctat
   770761 aggcatggtc atacacgaac tggcgaccaa tgcgtctaaa tacggagccc tgagcaaatc
   770821 cgaggggaag gtactggttg gctggcaatc ggcgaatggc gtcttccgac tcacctggca
   770881 ggaaagtgac ggtccgccgg tgagtgaacc ggagcgggag ggcttcggcc tgtctctgct
   770941 caaaggagaa ataggctaca ggctcgatgg cgaggtggaa acgttcttcc gtccggaagg
   771001 tctgttcgtg cgcatagctt ttccgttcga aaggtaggtg agctaaatgg aagtgcgcgc
   771061 tcgcatcctc attgtggaag atgaatggct catagcggaa gatcacgcgg cgagcctccg
   771121 cgaagcaggt tatgtggtgg ttggccccgt cccatcggtg aagcaggcgc ttcaggcgat
   771181 ggaaaatcag gaaatcgatc ttgcccttct cgatattcag ctttggaagg aaatgagcct
   771241 gccgctggcg gaacatctga aagccaaagg tgtgcccttc gcgttcctca gcggctactc
   771301 cgaccagaag ctgccgccgg acctgagtga tcgggaggtc attccaaaac cggtcgatgc
   771361 ggcctttctt gccgaggccg tcgcccgtct ctgcaagcat acgggctgag acaagagcgg
   771421 gatatcgatc gcgaagatca ctccggcatc ccggcaagcc gcaatccgtc tgcgaaccgc
   771481 gcgaaatctt cttggcgctg gatcggcagc cagtcccgga gattggatac acgcaaggag
   771541 ggatcgagcg cgcgcaggcg ccgcatcgcc agacgtgcct cctcattgcg ccccgccagc
   771601 gcatggctcg cagccaccag cgcgaccgca accagcaggc tgggaaggtt ccccagcgct
   771661 ctttctgccc aggcggaggc gagatcgaag cggccggcga agaaatgcgc gagcgcggtt
   771721 ccggcctgca tccggaacat ttcctggtcc agcgggctta ggcgggcggc gcgctcgata
   771781 tgttcgatcg cgctctccgg ttcgcctcgg aaaacgcgca ggaagccgcc aagaaaccat
   771841 gccggagcga ggttcgggtt cagcagccgt gccctgtcga taagcgcaat tccgccgtcc
   771901 aggtcgccga cgagatggcc gagtgcgtgc ccgctcctcg tcagcgccac ggcatcatca
   771961 cgaccgagtt ccactgccag ccgcgccagg cgcgcgccct cggctatctc ttgagcacgg
   772021 tggatcatcc agccgttcaa cttgcgccag aaatagcacc aggccgcccc ggcataggcg
   772081 gacgcaaaat cgggatcgag ctcgatcgcc ttgtagaaca agggcagcgc tgcttcgatt
   772141 gcttcgcggg ttccgttatg caggtgtgcc atgccgcgca agtaatagtc gtaggcgtcc
   772201 aggctcccgg tcggcttccg cttggcacgc tcgatttccg cccgctcgag ctgcggtgcg
   772261 atcgcgccga cgacgctctc ggcaactctg tcctgcaatt cgaaaatatc gtcgagcgtg
   772321 ccctcgaagc gctccgccca cagatgcgtt ccggccgttg cgtcgatgag ctgtccggtg
   772381 atgcgcactc tgttcccggc cttgcggacg ctgccttcca gtacgtagcg aacgccgagc
   772441 tcctggccga cttccttcaa gtccacctcg cgccctttgt aggtgaagct ggaattgcgc
   772501 gcgatgacga acagccagcg gatgcgcgag agggcggtga tgatatcctc caccacccca
   772561 tcggcaaaat aatcctgatc cgcatcgccg ctgaggttct ggaatggcag gacggtgatg
   772621 gagggtttgt ccggaagggc gagcgcgggc ggcggctcct tcgatcctaa ggatgtatgc
   772681 ccggcgctgc ctggcccgcc gggctgccgc gcttctgcgc tgtcggcgat cctgatgtcg
   772741 ccgacgaaac ggaagccctt gcgggcgacc gtccggacca ggcgctgttc tccgccggtg
   772801 tcgccgattg ctttacgcac cgcgttgatg tggcttgtga tcgttgattc cgagacgatc
   772861 cgcccgcccc acaccgcctg cagcaactcg tccttgctga cgacgcggtc gcgcgtgccg
   772921 accagatgga gcaacaggtc gaagacctgc ggtccgacgg acacgacctg cccacgtagg
   772981 gtcagttccc ggcgctcccg gtcaagtaca tagtctgcaa acatgaattg cacggtggta
   773041 tccctcggcc ggtcggcccc gcccgcgcgg gcagccggcg aatagatctg acatttataa
   773101 tacggcagcc cgaaattggc tgtaccgctt aaactatttc ctatccgggc gatctcacga
   773161 cccactcacc gctgcacggt ctcatgtttc attcactaca gcacgatatg tcgaccgaac
   773221 aaccggccct tggacgaaaa accaagcttc cttgaagagt aattcaagcg cgtcacaggg
   773281 acttccctga ggtgtgccgg cactctgcct acagatcgac ggcaatggtt gcggttgata
   773341 agaagcggag agacagtatg aagatcgtcg tcatcggagg caccggcctc atcggatcga
   773401 agcttgtagg caaccttcgc gagcgcggcc atgacgtgct tgcagccgcc cccaatacag
   773461 gcgtgaacac catcactcgc gagggattgg cggaagcgct gaacggcgcg gatgtcgtcg
   773521 tcgatgttgc caacgcgccg gtatgggagg ataaggccgt cctcgacttc ttcgaaacct
   773581 cgggccggaa cctgctggcg gcggaagctg ccgccggcgt ccgccatcac atagccctgt
   773641 cgatcgtcgg tagcgagcgg cttccagaca acggctattt ccgcgcgaag gtcgcgcagg
   773701 aaaacctcat aaaggcatcc ggtatcccat acaccatcct gcgtgccacg cagttcttcg
   773761 aatttgtcgg cggcatcgcg caatcggcca ccgccggcca ggagattcgc ctgtcgcctg
   773821 cgctgatcca gccgatcgcc tcagacgacg tggcggaagc gctcgccgat gtcgcggtcg
   773881 cactgccggt caacggcacg atcgaaatcg ccggtcccga ggcgataccg ctcgatgaac
   773941 tggtcagacg cttcctgcgg gcgaccgagg accagcgcaa ggtcctgccc gatgtccatg
   774001 cgcgctactt cggcgccgtt ctcgacgatc aatcgctgac ccccggggat aacccgcgca
   774061 tcggtgcgat ccggttcgag gattggctcg gccggcaagc cgccggctga ggctcgcagg
   774121 aagcatcgaa acaggccggc ccggcacagg ccgcgcccgc gccacaagca ctctcaagga
   774181 gaactgaaat gtacagtcga ttcctctcgg ccgttgctct tgcagcgctc tcgttcacta
   774241 cagcttcggc cggcgacagg cccgccggca aggttacggt cgtcttcgac cacgtccttc
   774301 cgaacgtgcc cggcaagagc atgaggggcg ttcttgtcga atacgaaccg ggcggcgggt
   774361 cacccgccca cacgcacccc aagtccgcct tcatctatgc cactgtgctc gagggcgcga
   774421 tccgcagcag cgtcaacggc tcgccggaaa aggtctatca ggtcggcgaa aacttctacg
   774481 aggatccagg ctcccgacat gaagtaagcg tgaacgccag cgacacggaa cccgcgcggc
   774541 tgctggccgt gttcgtcctc gacaccgagg aaaaggaact gaccacgccc atcaaggagt
   774601 gaacggttag gaggttatca acgctgcagc cctttcgcag cccctgcggc agggctgcgg
   774661 caaccggcac caacgggatt tgaaaagatg gactcgctcg aggacaagat cgccatcatc
   774721 accgacgcaa gttcagcgaa tggtgtcgcc acgtcgcgat ccgtcaggag aaagatgatt
   774781 ggcctggtgc tgtgcctcgg gtcggtcgtc gtcgtggcaa ccggatggtc gtggacctgc
   774841 gagaacggtg cgatgtcgac cgacaatgcc tatgtccgcg gcgacgtcac cgcgcttgcc
   774901 ccaaaggtcg cgggctatgt cacggcggtg ggggtcgagg acaaccaagc agtccgggca
   774961 ggcgacatcc tgttccgcat cgacgatcgc gactaccgcg caaggctggc gcaggccgtg
   775021 gccaatgtcg aagccgcgca ggcgcggctg accaatgtcg atgcggagaa ggagcttcag
   775081 catgccctga tccgccaggc cgaagcgcag cgacgttcgg ccattgcgga gctgaatctc
   775141 gcgagcaagg catatgatcg ccgccgcgaa ctcatccgga gcaacaccgt aagccaggcg
   775201 catgtcgacg aaagcgatgc tgccaggtcg agagccgagg cgaacgtgtt ggcggcttcc
   775261 gccacggtag aggctcagca gcagcgcatt gccgtgctcg cggcgcagcg ggaagccgcc
   775321 gtcgctgcgg tggcgcaggc acaggccgcg cgcgccctcg ccgaaatcga tttagagagc
   775381 accgtggtgc gcgcgcccgt cggcggcgtc ataggcaacc gccaggtccg cgtcggccgg
   775441 cttgttgcgt cgggcgctcc gctgctggat gtcgttcccc tcgacaatgt ctggatcgtc
   775501 gcgaacttca aggaaactca gctcgaacac ctccggcccg gtcagcgcgc cagcatcacc
   775561 atcgacggtt atccgaacgc ggtgctcgaa ggcgtggtcg acagttttgc gccaggcagc
   775621 ggcactgcct tcagcctgct gcccgcagac aacgcaacgg gcaacttcgt tcgcgtcgtc
   775681 cagcgcgtgc ccgtgaagat ccggtttgcc ggcagtccgc tgcccggccg cctcgtgccc
   775741 ggcctgtcgg cgcgggtcga gatcgatctg gagagcggtt catgaccatc gccagtgcca
   775801 caccgagccg cgagatatcc atggcaggag gccttctcgt cgccggtatc gtgcttgcga
   775861 cgctgaccga ggcgatcgcc agtacggtcc tttcgctcgg gcgcggcgat atcattggcg
   775921 acacctatgc aacgcccgac gagttcgcct ggctggatgt cggttacacc actttcaagc
   775981 ttatggggtt catggcggct tcctggctga tgagccgttt cgatccgcgc aacgtgatcg
   776041 tcagctcgac cctcgccatg ggcatggcgt gcggcattgc cgccatgacg gctcgattgg
   776101 accttctcgt cgcgcttcga atgatacagg gcttttccgg cggcatcctg ctggtcggcg
   776161 ggcaggcggt catctttctg gcttttgcgc gatcgcgcca gccgatcctt caggccctct
   776221 tcgcgatggg gtccgtcgtc gcacctgcga cgatcgctcc tgcccttcag gggtggttgc
   776281 tcgatagccg gtcatggaca tggatcttct tcagcgtcgt tccgttggcg ctggcggctg
   776341 ccgggcttct gctgatcgcg gaccggccga tgcctgcacg aaacgtgccg cggccatttg
   776401 actggatcgg tttctccctg atctccattg cgctgtcctg ctttacctac gtctttagcc
   776461 agggcagccg gtgggactgg ttcgaggaac cgcgtatcct gtggctgtcc gtgatcggca
   776521 cggctgcgat tctggctttt ttcggccagc agatgctcgc caagggccag ggcctgttcg
   776581 acttcacgct gttcggaacc gaggatttct gcttcgcctt catcgtcagt ttcgttgccg
   776641 gcgccgcatt gttcgggagt gcgttcctga tcccgtcctt tgccgtgtcc gtgcttgcgt
   776701 tcacgccgac agacgccggg caactcctgc tgccgagcgg cgcgctcttc atcggcgcgc
   776761 ttctcatcgc cgcctttctc atgcaggccc gccgtgttcc ccccgtcgcc accgtgcctt
   776821 tcggcattct gatgatcatg ggggcgatgt ggatgctttc cggatcgacc atccaaagcg
   776881 gcgcggacga catgatggca gcaattcttt tgcgcggtgc cgggctcggc ttcctgttcc
   776941 tgtcgatcac cctgatcgcc ttcagcgatc tcaaaagccg gaatctcgcc gccggtatcg
   777001 gtctcttcaa tacgggccgc cagcttggcg ggctcgtagg ggtcgccgca ctccagacac
   777061 tgatcgatca caacgtcgcg cataatcttg cggtccttgg cgccaacgtc accgcaggag
   777121 ccccctcggt cgccgagcga ctggcaacga gtgctgccat gttgacggcg aaagggatgg
   777181 acgcggctgc cgcgagccgc ggggcggcaa gccttctcgg ccgggccgcg gcaggtcagt
   777241 ccaccgtcat tgccttcgac accgcattca acgcggtggc gcttctcttc gtcattgccg
   777301 ctcccctgct ggtcggggtc aagataggcc tctcgcgatt gcgaaagcac gtgtagcgga
   777361 tggcggcgtc ggcacggcgg ccgatccgtt gcgtcataac acccaccgtt tgagcggttc
   777421 cgagcatcat aacgtctcgc ttttcgggac acggtcagtt acccgtatcg tcgagatcag
   777481 ttcgatcagt tcatatgcaa tgacgtgccg cgccggtggt aaagaacgcg cgcgtgcgtt
   777541 ccttcgagag ggacctgtcg aactgaagac ggagagtccg atgaagaatg cacaggaaaa
   777601 gactgcctct cgcgcggaaa gccggatcga cggcgagcag gtgcggcaaa tcgccctgcg
   777661 catcacgtct tggccgagcg aaaccggcac gccgggcgaa gcatccttcg cggatcgcct
   777721 tcatgctctt ctccgcgagc ttccctattt tcgggagcat ccggaagacc tgcacctcat
   777781 tgcaagtcac ggtgagccgc tgacccgcaa tgtcgttgcg ctcgttcgcg gcacgggtaa
   777841 gcgaacgctg gtcatggccg gccacttcga cacggtttcg accgacaatt atcacgagct
   777901 taaggccctc gcctgcgaca gcctggcgct caaggatgcg ctcatcgaaa gcctgtcggc
   777961 acgcgacgac cggtccgagc aggaagagcg ggccctgcag gatctggcga gcggcgactt
   778021 tctccccggc cgcggtctgc tggacatgaa gagcgggctc gcggtggcca tcgcctgtct
   778081 tgaacaattc gcggccgaca cgggccggca gggcaatctc atgctcgtcg ccacccccga
   778141 cgaggaacgc gaaagccggg gtatgcgatc gtttcgaaat gcattgcccg gtctggtcgg
   778201 ggatttcgat atcgagatcg ccgggggcat caacctcgat gtgacctcgg atcagggcga
   778261 cgggagcgaa ggccgggccg tttacgccgg cacgatcggc aagcttctgc cctttgcgct
   778321 ggtgatcggc tgcagttccc atgcgagcta tcccttcgaa ggggtaagcg cacaggccat
   778381 ggcagccggc atcctggagc gtctggaagg gaacgcttcc ctggcggatc gcgacgacaa
   778441 cgacatttcg ccgccgccga tctgcctgga ggcgaaggat ttgcgcgacg gttacgaggt
   778501 gacgacgccg gagcgtttct ggatagcttt caactggctc taccatgcga tgacggcgga
   778561 cgcactcttt gcgcgcttcc gagaggaagt gctgaccggc gcgaacgaag ccatcgagaa
   778621 gtttgcggca caatctgccg aatacggcag gctcgtcggc agacgggcgg gcgtgatgcc
   778681 ggccacgccg cacctgatgt cgttcgggga attgcgggcg gcggctgcac gggttttcgg
   778741 agacggcttc gacgcgttct atgccgagaa ggaaagcgta ttctctcaga gcgacaaccc
   778801 gctcgtcgcc acgcggcaac tgacggagtg gctcgtcggc atcgcgcgcc tctccggtcc
   778861 cgccatcgtc atcggatttg ccggcctgca ctacccgcct agccatctgc gcctgagcga
   778921 aggaaacgac cggtcccttc atcaggcggt cgagaaggcg cgtgccagtc tcggcaacga
   778981 tcccgcacga agcctcgtct ggaagccgca tttctacgga atctcggata tgagttttct
   779041 cgggcttgcg gcaggcgata gccacatcgt ttcggacaat accccaatct cgaggctcgt
   779101 cgatcggccg ggcgagaatg cgctgcgctt tcccacggtt aacctcggtc ccgggggagg
   779161 gagttccatc agaagttcga gcgcgtatac gcgccttacg ccttcgaggt cctcccggat
   779221 atggttttcg agatcgcgag gcgctttctc tccgactgca gtcactgaaa cggacgccgc
   779281 cttggtgcgc ttggcaacgg acacttttaa acaaggattg cgcaggcgcc ctaacgaggc
   779341 gccgcggttt tacgcgttcc ccctaggaaa tcagcgtagc ggtcgcccag cattatgacg
   779401 ggggcattga agtcgcctgc cgtttttcgt tttttgttgc ggccggggtc atcggcatcg
   779461 agtgcgggga caattttgca tacgcctgca aaaattcttg catacgtatg cataatgggg
   779521 ctatgatgac tgttgacgcc gccacaaggc gcgggagcaa acgcagtgtc accgaagagg
   779581 gacgccgcca acaaacaggt gggaacatga agaaaacggc attcttcgca tcggccgcta
   779641 ccatcatgct gtcgggcctc gtagcggttc aggccgcacg ggccgagtgc ggcatagaaa
   779701 agggcacggt gcgcatcctc tcgaacgatt tcgaagccct gcgtctcgtg gtgtcggaag
   779761 ccgagaaatg cgcctcggcg acggtcaagg tcagcaagaa ccaaacgagc gagcacaaga
   779821 acctgcaagt gccggcgctc aagatcaatc cggcccaata tactgtcgcg gtgattgcca
   779881 acaattcgat cgttccgctg ctgaacgaag gtctgctgcg cccccttgac gatctcgttg
   779941 ccaagtacgg ccaggatctc cagccgaccc agctcatcaa actcgacggc aaggttatgg
   780001 cgatcgcctt catgggcaac tcgcagcatc tattcttccg caaggacatc ctcgaaaagg
   780061 ccgggcttca acagccgaag tcctatgagg acgtgctcgc agcggccaag gcgatcaagg
   780121 agaaggggct gatgcagtat ccgctcgccg cctccaacaa ggccggctgg gatctcgcgg
   780181 ccgaattcgt caacatgtat ctcggctatg gcggagagct cttcgcggcc ggttcggcag
   780241 cccccgccat caacaacgag aagggtctcg ccactctgaa gacgatgaag gcgatgaccg
   780301 agtacatgaa ccccgactac atgacctaca atgccgacga gatcgtcaag ggctatgcgg
   780361 ccggcaagac ggcgatcatc aatgcgtggg gctcgcttgc gggcggcgtg atcgatccgg
   780421 tcaaaacgcc ggccgagatc gccgacaaca cggttctcgg cgcagcgccg accgttgggg
   780481 gcggctcgat ccctgcagcg gccctctggt gggacggttt ctccatcgcc aagaacattt
   780541 ccgacgaaga tgcggaggca tctttccgcg ccatggtcca tggcatccgg ccggaagttg
   780601 gccagaaaca tccggctctt gcgacctggc tgaccaaggg gtaccagcct ggacccaacg
   780661 cggtcggggt tctcgcgacg gcgaatggcg gcgcgaagcc ctatccgatg ctgccttata
   780721 tgggcctgct gcactcggct ctcggctccg aactggcgga gtacatgcag gggcgtgaaa
   780781 gtgcagagga ggcgctgaaa gatgtcgagg catcctacag cgcggcagcg aaagagggcg
   780841 gattcctgaa atgagcctgg atgcaggtgc gcgccgcttg gccggcgctc ccctcgacct
   780901 gtcgagatgt cccgctccgg cgggatgaaa tttaacctgc aaaatgagca aggagagggc
   780961 gcatgcctca cagggctttc tttgccttta tcatgccgtc gctgctggcg atgctgctct
   781021 tcatcgcctt gccgatcgtt tccgtcgcgg tgcagtcgct ctatgtcgag cacgagcgtg
   781081 tcgtaacgga agtcgagacc tgcgcgccct tcgcaggctg caccacggaa acgcgcgtgg
   781141 atgcggaggc gaccgagaaa ttgcgcgatg cggagccgct cggccgtttc aacggcttcg
   781201 gcacctatct cgatcgcaac catctggcca ccgccgaaat gaacgcgatc ctgacggata
   781261 atgccggttt cgcggatgtc gcttcgcgca tctacaatct gccgttctac agggcgctcg
   781321 ccttcaccct gacctacacc ttcgtcgtca cgccgctcgc catgctgctc ggcttctgca
   781381 tcgcccttgg ggtgaacgcc attccgccct tttacaaagg ccccgtcatc ttcttctcgc
   781441 ttcttcccat gattgtgaca ccgctggttg gcgcgctgat catctactgg atgtcgtcgc
   781501 cgcagggcat cctcggcgcg accctgcaat cgctcctgaa cgattcgacc ttatcgctga
   781561 aatcatcggc ggttctgacc tgggtgacgc tgctcgtcta tggcgtctgg cacaatgcgc
   781621 cgttctcttt cgtcgtcttt tatgccggcc tgcaaaccgt gccgcacgat acgctcgaat
   781681 ccgcgatgat cgacggcgcc aaccggtggg agcgcatccg cttcgtcgtg atcccgcatc
   781741 tgatgccgct cgccacattc gtcgccctgg tgcaactgat ggataatttc cgtgtcttcg
   781801 agccgatcgt cgggttcagt gccgaggcga atgcgacctc gctttcctgg tcgatcttca
   781861 acgatctgcg cggccaggtc gatcagctct tcggctcggc cgctgccact tcgatgctga
   781921 ccatcgtcgg ggtcgttatc ctgctatcgc cggtgctcgt gcgcacctgg cgtgaattca
   781981 accgtcgatg agggcgccgc gatgatcgtc aacaaacgca gacgtcccct gccgctcaca
   782041 gtcctctcca ccaccttcgt gctgctctgg gtgctgatgg cggcctttcc gtttatctgg
   782101 acggtctggg gatcgttcaa agtcgagcag gactttttct cccgcgacag ctggtggttc
   782161 gccatcgagg gttcccgcac gatcgcccag acaggctccg ccttcaccgg cgacggctat
   782221 tacggcgcct gggtgctgcg cgacttcttc tcctcggtcg tcaacaccgt catcgtcacc
   782281 ttatcggtgg ttgtcgtctc gctcacattc ggcacgctcg gcggctatgc gctggcgcgc
   782341 tccggatatc gctatacctt ctggctcctg atgctcgctc tggtgttccg tgccatgccg
   782401 cacatcaccc tggtctcggg ctatctgctg ccttttttcg agatgaacat ctggggccac
   782461 ctgccgaccg ccatcatcgt gcttgtggcg atcaaccagc ccttcaccct gtggatgctg
   782521 cattccttct tcctgtcgat ccccaaggat ctcgacgaaa gcgcaatggt cgacgggtgc
   782581 tcgcggttcc aggcattccg cctggtcgtg attccggtca tgtggccggg cgtgatcacg
   782641 acgggcctgt tctccttcct gctcgcctat aacgacttcg ccgtgactgc gatgctcctg
   782701 tcgcagccga accagaccat ggtgccgaag atcgcgagct tcctcgggac gatccagcag
   782761 gaaggcaatg tcatgttcgc cgtcgcagcc gtcgtctccg cgaccgcacc gctcttcgtg
   782821 ctggtcatgt tcttccaacg tcagatcgtc agcgggctca ccgcgggcgc agtcaaggga
   782881 taatcgcaat ggctgaaatc cgcctgaaga acgtgtcgaa gcgttggcac aatttcgtcg
   782941 gcgtcgacaa tttcgatctc gacatcgccg accgggagtt cctggtgctg ctcgggccgt
   783001 ccggctgcgg aaagacgacg acgatgcgca tgatcgccgg actcgacgat atcagcgaag
   783061 gcgaaatctg gctgggcgac cgcatggtca acaatctgga gccgaaggac cgcgacatct
   783121 cgatggtctt ccagagctac ggcctctatc cgaacatgac cgtctacgag aacatccgtt
   783181 ttccgctgcg cgtgcgaaag gtgccgaagg aactgcacca tgaaaaggtc atgcaggccg
   783241 cccgcatggt cgagctggtg gatttcctgg agcgccggcc ggctgcgctt tccggaggtc
   783301 aacggcagcg tgtcgcactc gggcgcgcca tcgtgcgcca gccggcagcc ttcctgatgg
   783361 acgagccgct atccaatctc gatgcgaagc ttcgcgtgtc gacgcgtgcc cagatcaaga
   783421 acctgcagca cacgctgaag gttacgacga tctacgtcac ccacgaccag atcgaagcga
   783481 tgacgcttgc cgaccgggtg gtagtgatga acaagggcgt tatccagcag gtcggtacgc
   783541 cgacggatat ctacgacaac cccgccaata cctttgttgc atccttcata ggttcgccgg
   783601 cgatgaacct tgtctccggc gacatcgaaa acggcacttt ccgagggccg ggcatcacga
   783661 tcggcggtct gcagatcaat gtgaagggcc cggtgacgct cggcttccgc gccgaagacg
   783721 cctcgctcgt ctttgaaggt ggcgagcttg gcgccgaaat ctattctatg gagctcctcg
   783781 gcgaggccac catggcaagc ttccggatgg gcgatcagct cgtctcgatc aaatccggca
   783841 aggaataccg ggccgagatc ggcgacgtcg tgcatgcggc gatccccgct tcgatctgcc
   783901 acctgttcga cgccaggacg ggtgtgcgga tcgcacgaac ccccggcaac tgaaatccat
   783961 gatcggcatg cggtctcgcg tgcccgatcg ttccaaggga agaacaacat gacggtgacc
   784021 tatctcaagc gcggcaagcc cgaggcccag cgatcggagg aagatgcgaa ggtccgcggg
   784081 atcgtcgagt cgacgcttaa ggacatcgag acgcgcggcg accaggcggt tcgagaactt
   784141 tctgagaagt tcgacaggtt ttcgccgccg tctttccggc tcagcccatc ggagatcgag
   784201 gcggccatgt ccagggtctc aacgcgcgac atgaccgata tcgacttcgc ccagacgcag
   784261 atccgccgct tcgccgaggc gcaacgcgcc tcgatgacgg atatcgagat cgagacgatt
   784321 ccgggggtaa tcctcggtca tcgcaacatt cccgtacagt cggtcgggtg ttacgtgccc
   784381 gggggcaagt tcccgatggt ggcctccgcc catatgtcgg tcctgacggc cgcggttgcc
   784441 ggcgtgccgc gcatcgttgc ctccgctcct ccccagaagg gtgcgccgca tccggcgatc
   784501 gtggcggcga tgcacaaagc cggtgcccac gaaatctacg tgctcggcgg catgcaggcg
   784561 gtcggcgcga tggcgctcgg aaccgagacg atcaagcccg tcgacatgct ggtgggtccg
   784621 ggaaatgcct tcgttgccga agccaaacgg cagttgtacg gccgcgtcgg aatagatctc
   784681 ttcgccggtc cgaccgagac gatggtgatt gccgacgaga cggtggatgc ggagatatgc
   784741 gcaaccgatc tcctcggtca ggccgagcat ggttacaatt ctccggcggt gcttgtgacc
   784801 aattcacgca ggcttgccga tgagacgctt gcggaaatcg gccggcttct ttcgatcctg
   784861 ccgacggcgg acaccgccag tgcctcatgg cgcgactacg gcgaagtgat cgtctgcgac
   784921 acctatgagg aaatgctcga cgtcgccaat gaaatcgcct ccgagcacgt gcaggtcatg
   784981 accgatcgcg atgattggtt cttggagaac atgcattcct acggtgcgct tttccttggg
   785041 ccacgcacca atgtcgccaa tggcgacaag gtcatcggaa ccaaccacac cctgccgacc
   785101 aggaaggcgg ggcgctatac gggtggcctc tgggtcggca agttcatgaa gacgcattcc
   785161 taccagaagg tgctgacaga cgaggcggct gcggaaatcg gcgcctattg ctcgcgcctg
   785221 tgcctgctgg agggctttat aggccatgcg gagcaggcca atgtccgggt tcgccgatac
   785281 ggcggacgca atatcggcta tggcggcgcg gcgtaggccg ccggattttc aggaggcaaa
   785341 tttggacggg tttcttcata tcggctgccg cgtggcgcta cgcgcatgcg tcagcgcgcc
   785401 ggttctggcg gtgaagcagg ggagccgtcc gtcatgaagc tgccgcgcac accctctttc
   785461 cgtctcgacg gcaggcgcgc cctggtcgct ggagcctcgt ccggcatcgg tctcggttgc
   785521 gcggtcgcgc tggcggaagc gggcgcccat gtggttctgg cggcgcgctc gccggagaag
   785581 cttgacgaag cggtcgaggc gatccgtagg gaaggtcttt cggccgaagc cctggtgctc
   785641 gatgtcgccg acctcgaggc gaccgaggct gccgtcgcgg cggagcggcc gttccaggtt
   785701 ttggtcaaca gcgcgggcat cgcccgtcac ggaccggcgg cggatacggc tccggaggac
   785761 ttcgacgctg ttttcgggct caatgtacgc ggcgcctatt tcctgacgag ggccgttgcc
   785821 aaagggctca ttgcagccgg tcaaccgggt tcgctcatca acatctcctc gcagatggcg
   785881 catgtcggcg gcatcgaccg ggccgtctac agcgctacca aacatgccgt cgagggcttt
   785941 accaagtcga tggcgatcga gtggggaccg gcggccattc gggtgaatac catctgcccg
   786001 acattcatcc gcacgccgtt gaccaagcag acattctcga agcctgaacg ggtccaatgg
   786061 ataacggaga aaatcaagct cgggcgtctc ggtcgcgtgg aagacattat gggtgccgtc
   786121 acctatcttg cgagcgatgc ctcggcgatg gtgacgggaa ccgcgctgat ggtcgatggg
   786181 ggttggacag cagactgatg gcaaacgata aggtcacgtc gaacgatgtt gcacgcttgg
   786241 cgggcgttag ccaatcggcc gtatcgcgct atttcacgcc gggaacgtcc gtttccaaaa
   786301 agacggcgga gaagatcagg gcggccgctg aagagcttgg ctaccgtcct aacgtgcttg
   786361 cgcgctcgct gatcaccggg cgcagccgca tcatcggcct cgtcgtggct tatctggaaa
   786421 actacttcta tccggaagtg gtggagcgtc tgtcgaaagc gctgcaggac cagggctacc
   786481 atgtgctggt cttcatctcc tcgatcgcat cggaaaacgt ggaccagatc acccaggaga
   786541 tcctggacta tcaggtggac ggcatcgtgc tcgcttcggc gaacatgtcc tccgaactgg
   786601 cggcgcgatg ccacgcctca ggcgtgccga tcgtgctgtt caaccgcctt caggacgacg
   786661 agcggctctc cgccgtcacc tcggacaacc gtgccggcgg ccgccagttg gcggagctgt
   786721 tcgtttcgct aggccacagg cgctgcggct acatcgccgg tttcgaaggc gcctcgactc
   786781 agcgcgaccg ggaacgggga tttcgcgagg ggctggaggc ggcaggcctc ccgctttctg
   786841 cgcgcgaggt cggcaacttc cgatatgagg acgcgcaggc cgcggcacgg cgcatgtttg
   786901 ccggcccaga gcaccccgac gccgtcttcg tctgcaacga ccacatggcc ttcgcggtga
   786961 tggacgtgct gcgcttcgaa ctggggctcc gcattcccga cgacgtttcg gttgccggct
   787021 tcgacgatgt gccgccggca cgctggccgg cctacaacct gacgacgatc cgccagaacg
   787081 ttgacgacat ggtcgccgaa acggtggcca cgctcatgca cagcatcaag gagggcgaag
   787141 gggcagcgcg ccgcatcacc ctcgacggcg ctctcgtcct gcgcggctcg acccgcgcga
   787201 aagctctgac agaagagacc cgctaacgac gccgcccgat gggcggagcc atgaccgcaa
   787261 cctgttttgc atacgtatga aaggctgaaa aatgcagatc tcccagacgg aaatggaaaa
   787321 gcgcatcgtg cgctacggcg agctgaaacc gtgccgcacc gcattcatcg acgcccatac
   787381 gccaggctcg aaccagaaag agaacttcac gattatcggc ggcggcgttt cggaaagcgc
   787441 cgatcagcac gtccatatca aggacacgcc aggcttcaac ataggagcgg ccggtcagcc
   787501 gccgaagtgc cgcaactcgc tgcattcgca tcgcacggct gaagtcttct tcgtgctcaa
   787561 gggccggtgg cgcttcttct ggggccgctg gggcaatgcg ggcgaggtgg tgctcgagga
   787621 gggcgacatc ttcaatattc cgaccggcat cttccgtggc ttcgagaata tcggtacgga
   787681 ctacgggatg atcatggcca tactcggcgg cgacgacgcc ggcggcggcg tgatctgggc
   787741 gccgcaggtg atcgaggatg ccagggatca tggcctggtg ctcggtgaaa acggcaagct
   787801 ctacgacacc aaaaagggcc agtcactgcc cgatggcatc aaaccgatgc cgcttctgac
   787861 ggaggaagag ctgaaggcct tcccggagac gccggttcag gaggtggttc gcgactatgt
   787921 tgcccgttac tgggacctga tggcgcttgc acagaaagca ccagccaagg tgatcggcga
   787981 aaaagcgctg ctccgtgaca agccgggttt cgaggttgaa ctgctcacgc gcggatcgat
   788041 cccggaggcg gcctatgtga acgagcgtca tgaggtgctg atggtcatgc gcggccattg
   788101 ggagcttgcc tgggacggcg gcgcatccgt gctggcgccg ggcgatacct gtgccgttcc
   788161 gccgggactg cagcacagcc tcgtgccggc aatgacggga gaggcgagcc tctatcgcgt
   788221 ggttgccacc ggcgaaaagg ccggccggac ctggcgcggc tgatctagag catttccgct
   788281 tttctccgaa tcgcggaaac tctccaaccc tttgttttgc cgcaattccg gacggaaaac
   788341 cgttacgcac tttttctgga attgctctgg cgaagggcgg cagagggccg cccttcatca
   788401 cccctgaggt tacggcccga aaaacggatt accggaggaa aagatttgga cgacgaactc
   788461 ctgtccctgc tgctcatggt cgacacgccc accgtctgca acgcgatcga ggtggcgcag
   788521 ggcaagcgcg gcttcgacgg ttttacccgc ggcacggtcg tcagctcggc accaacggcc
   788581 cgtccggtcg ttggctatgc ccgtactgcg aagatcgccg ccgccgctcc ctcgaccgaa
   788641 ggaccagcgg tcatcaaggc gcggcgaatg gattattacc gccacgtggc gagcggcgct
   788701 ccgccttccg tcgcggtcgt cgaggacatg gattatcccc attgcgtcgg cgccttctgg
   788761 ggcgagatca acgcgaccgt ccatcgcgga ttgggccttt gcggcgtgat gaccaatggc
   788821 gtcatgcgcg acctcggtga tgtgcccgaa gacttcccga tgatcgcagg atcagtcggc
   788881 ccgagccatg ccttcgtgca tgtgaaggcg atcggcgttc ccgtctccgt gttcggcctg
   788941 acggttgcgc cgggtgacct cgtccatgcg gaccggcatg gcgctgtcgt ggtgcccccg
   789001 gacatcattc ccgtccttgc agccgcgatc gagaagctgc gcgccaccga gcggctgatc
   789061 cttgagccag ctcgacagca aggcttcgat ctcgcaaaat tcgaggaagc ctgggcccgc
   789121 ttcgaggccg cccggacctg actggagcgc tccatgccgc atcccacgcc gccaagcctt
   789181 gccacaatcc ggaaacgggc tcgcgccctt ggcatttcca tcgccgtaga gcgtgaggca
   789241 tccgttcggg ccggtgccca gcatcttcat gatgcggtgc agcgtctgga ccgtatcgcg
   789301 gccgacgacg aagccttgcc ggagtctgat cgcagatgat cgagaatccg gccgacctgc
   789361 cgattttgga agctgccgag cggttacggg atggcagatt gacttccgtg gcgctaacag
   789421 tggcccatct cgaccgtatc gcggaacgga acggcgccta tcacgccttc ctgcatgttg
   789481 ccgctgaaag cgcgctggcc gaagcggcac gcgcggacga ggcgcttggc tgcggcgaag
   789541 accgtggtcc gctgcacgga atacctgtcg cggtcaagga tctcttcgat acggccggca
   789601 tgcccaccac ctacggttcg gacgtctatg ccggctatct cccgaccgag gacgcggagg
   789661 tcgtgcgcag gctgagagcc gccggcgccg ttctgatagg caagctggaa acctacgaat
   789721 tcgcgatggt cggtccagtc ttcgaccggt cctttccacc ggccgccaat ccctgggatg
   789781 ttcgtcgctt caccggcggc tcgtcctccg gctcggcagc ggccgtcgcc ggcggccttg
   789841 ttcgcacgtc ggtcgcctct gataccggcg gatcggtgcg aagccctgcc gcctattgcg
   789901 gggtcgtcgg cttcaagccg acctatggcc gcatcccggc acgtggggtc tttgtcctgt
   789961 cgccaagcct cgatcatgtg ggtctcatca gtgcctcggt tgccgaagcg gcgatcactt
   790021 tcgacgctat cgcagacgct gaaacgacag atgcggagcc cgccgcctca cgccttggcg
   790081 gggctttgag cggactgcgc atcggctatg cccgtaaatg gtttgccgac gacccggaga
   790141 cgctgccggc gcttctcgat gccgtcgacg gagccgcatc gcagctgtcg ctgctcggtg
   790201 ccaggataga ggaagtggcg cttccggccg ccccggattt cgagtccgta ggagccgtca
   790261 tcatccatgc cgaagccttc gaggcgcacc ggcggcaatt ggcagcctcg ggtgacggct
   790321 acagccgcaa agtcttccag aacatccttt ccgggctgtg tctgacgccg gaagaccttg
   790381 tccgcgcccg gcacgcggcg gcgcgtctgc gggaccggat cgaccgcacc gtctttgcgc
   790441 gcttcgacgc gatcctgacg gcgacgactt tgacgccggc gatacccttt gccgattttg
   790501 ccggagaagc agcgcgatgg acaccgatgc gcaccatcgc cttcaatgtc acgggccacc
   790561 cggcgctgtc ggttccctgc ggtttcgcca acggattgcc gctggccatt cagcttgccg
   790621 gcagggcagg ggacgaggcg accctctgcc agataggcca cgcctatgag caggcgagcg
   790681 actttgccgc gtccaagccg ccgcttccat tcccgcgtgc ggcgagcgac gggagaaccc
   790741 aaccggcacc ttccgaataa caggatacaa atttaattgc atacgtattc aaaatctgcc
   790801 agtctttctt tcagcaggtg tcacggtctg cttttgccgc atccgagaga gtggcctggc
   790861 gtggctgtgc gcgaacccct ccgagcgagt tgacgatgac cgcttccccg aacgacgaac
   790921 cgcgaccgcc gcttctgctt ctgccaggca ccgcgtgcga ccagcgagtc tttgcgtccc
   790981 tgatcgacag gctcggcgat tatccggtcc tgatcgggga catgggcggc gctcggacaa
   791041 tggcggcgct cgccggaaat atccttgcgg ctgcaccgcc ctattttctg ctcgccggct
   791101 tttcgcttgg cggcatttgc gcgcttgaaa tggtggcgca gcagccggag cggatcggaa
   791161 agctcgctct gatcgatacg accgcgcgcc ccgatccggc agaaaatgcc gcggtccggc
   791221 gcaaggcggt tgcggatgcg cgggagaagg gaatggacgg gtttatcctt gataactggc
   791281 cgcgactcgt cgccccgacc aatgtccatg acggaagcct gcgcgacacg atcgtcgcca
   791341 tggcgcgcga ttgcgggcct gaccggcttg ccgagcacgc ggaagtcgcc atcagccgcg
   791401 ccgacagccg gcggcgtctt gccgagatca ggcaaccgac gctggtcctt gcaggagcgc
   791461 atgaggaggt gtgcccgctc gatgcgcaac aggaactcgc tgccggaatt cccggcgcgg
   791521 agctccatct catcgcagaa gcaggccatt tcgcaccgct tgagaacccc gatgccgtgg
   791581 cactcgtcat gaagcgctgg cttgaggccg gttccggccc cttttcgtaa cctatagaat
   791641 ccaatggaag gacattgcat gagcgacgac actaccaagg cagtaaaggc cgtggcgcag
   791701 aaccagcgta aggatccggc ggaacaggtt ttgcaggtcg aacgccggga ctataccgag
   791761 cttgctcccg tagaccggcc ccgcagccag tcgctcgatg gcttcgacga gatctacacc
   791821 gacattgtcg attatatcgt ccgctgcaca catcgcatct gggacgagcg tgacatcggg
   791881 ctgatctata cccactatac ccacaactgc gtcctctacg gcacgctcgg caccatctat
   791941 aatcgcgagg atgtggtgcg cgacacgatc cagcggctgg tctcgctgcc ggagcggcgc
   792001 ggcatggcga cccaggtgct ctggagcggc aacgatgtcg aaggcttcta cacctcccat
   792061 ctcgtcaccg ggtccggccg gcacacgcaa tatggccatt tcggcccgcc gaccggccgc
   792121 actttcgtgg cgcgtacgat cgcggactgc atgatccacc gcaacaagat ttaccgtgaa
   792181 tgggtggtgg ccgatacgat ggccatcatc aagcagctcg gcctcgatcc gcacgccttc
   792241 gccggaaagc ttgccaggtc ttcatttgac aaaggacttc tctcgcttga tatcggcgag
   792301 aaccgccgcc tgctcggcca atatccgccg gaggcggaag cggacgtctc gatcgcgcat
   792361 aacgatatcg aagcccatac gttgcgttgg ctgcacgaag tgttcaacgg gcgcatgttc
   792421 ggcaggatca aggatgtcta cgctcccacc tgccagtatc acggcccgct gatgaaggag
   792481 ctttacggcg tggcggccgt cacccatcaa caccttggcc tcatcggctc gatccccgat
   792541 gccgcctatt ctgcgcagca catctgctcg aacccttgcg aggaaggcgg cgtcaaagtc
   792601 gctgtacgct ggctgatgga aggccatcac ctcggctacg gtatattgca ggacctcggc
   792661 gagccgaccg gcgcccgatt gcaggtcatg ggcatgaccc attaccacta caaggacgga
   792721 aagatcgtcg acgaatggaa tgtctacgac gagctgtcgc tgctggtgca ggtaaagctt
   792781 gccgaaatgg ctcgccagtc ggggtcagcg aatgcagagg ctcacggggc cagttagacg
   792841 agaacaacgg tctctcggcc gcggggcgtg gtttcgaagc attggtgccg gcctttgccg
   792901 tagctgtgca aggctcgcct cgccacagca atctgctccg cctgcttcga ccaggaggct
   792961 atgcgcgtgg gtggtccggc gacgccgggc gaccacactt ttctgactcc gccctactcg
   793021 cgcaatgtga tccagaccgg cgcatggtcg cttgcccctt caagcccgcg gatttcgcga
   793081 tcgattccgg cgccggtcag ccggcgcttg agctttccgc tcaggagaat gtggtcgagg
   793141 cgaaggccgg cgtcgcgctg ccagcggttc cggcgataat cccagaaggt gaaaagctgc
   793201 gcctgcgggt ggaccttacg aagtgcgtcg agccatccct gttcaacaag gctcttgaac
   793261 gctgcgcggc tttccggctg gacgagagcg ttgccgtcgt aggagcgggt cggatagatg
   793321 tcgcgcggtt ccgggacgac attgtagtcg cccgcgagta acaccggaac gcgcgcttcg
   793381 agaagcgcgg cagcgtgcag attgaggcgt tggtgccagg cgagcttata gtcgaatttc
   793441 gggccgggct gcggattgcc gttgggcgca tagagcgagg cgatcaggat gccgttcacc
   793501 gcggcctcga tgtagcggct ctgcgtatcg gacggatcgc cgggcaagcc tgttcgcgtg
   793561 aggaccggtt cgcagccgcg ggcaagaatt gcaacgccgt tccaggctgt ctggcccagc
   793621 cagacggcac cgtaaccggc cgcctcgatc gcagcctcgg ggaactgtcc gtccgtcgcc
   793681 ttgagctcct gcagacagac cacgtccggc ccagccgctg ctagccagat caggaggtgg
   793741 tcgagtcgct tgttcacacc gttgatgttg aaggtcgcga tcttcatcgg gagctcaaga
   793801 cacgaggcgg cccgcccatc gggcagccgc ctcggccagc gtcttcaggt gatctgcggt
   793861 cgagaagccg gagatggtct tgcgcggctt gaggtcgtgg tcgccgtctt ccagccagag
   793921 gagttcgatc ctgtcggaga gagcatattg cgagacctcg tcgcgagtgc cgaactcgtc
   793981 gcgggtcccc tggcagatca atgtaggcgt ctggaggtcg gcaagatgcc gggtgcgcaa
   794041 ctgctccggt tttccgggag gatgaaaggg atagccaagg caaaggagcc cggcgatctt
   794101 gccctcggca tgaaggtcgt cggcgaccat gctggcgacg cgtccgccca tggacttgcc
   794161 gccgatcacg agtgcgcctt tgaagccgag ctcggcaatc gccgcccgat attccggatt
   794221 gagcgtttcc gcgcgcggcg ggggcttgcg cccctccgag gtgcgccggg ccgccatata
   794281 gccgaactcg aagcgggcaa cgcggaaacc tgcgccggca agcgcctgag cagtggcgtt
   794341 catcgatgcc gaatccatcg gcgctccggc tccatgcgcg agcagaatgg tgacgggcgc
   794401 atctcccggc ccgtcgaaca ggaaatttcc gcccatatta ccctgccgtt ctggagagga
   794461 gttgaaggtt cacgaattgc acgccgcgtt cggccttgcg cgcccattcg gaatcctgat
   794521 cgagttcgag gtagcgcatc caccagcggc gcgcctcggt gagattgccc gcatcgaact
   794581 ccagcttcgc caggttgaag accgcatcgg cataaccgcc gtcgagctcg atcgctttcg
   794641 tgagatgccg tctggccgtg tccctgcggc cgcgttcctc catcagcccc gcaaggttga
   794701 accatgcctc gacgaaggaa ggatcgagct tgatggcgcg ggcatagtcg tgcgccgctt
   794761 ccgcctcctg tccggcggcc ctgaggcagt tggcacgatt gaaggaagcg acggagtcgg
   794821 tgcggtcgat ggcgaggtag cgctggtaga atgcggccgc ctcatcgtag tctcccgctt
   794881 cctcggccgc ttcggccagc gcgaaaaggt cttcgagcgc ctcctcgtcc ggagagccga
   794941 catcgagcag catctggccg tcgagctcgc tcaagccctc ggcgcgtcgc gcatagatcg
   795001 tatcgtttcc ttcatgttgc agggagagtg cggtgaggga tgcgacattt ccggagcggt
   795061 gaaccgatcg cgcgatcgcg ctccatccgg cgccgctggc cgtcagcccc gcatatttcc
   795121 gggcgaggat caggtcacgg aaagaatatg gttcgccatc atgctcgaag gcgtcgaaca
   795181 gcgatagaag atcgaggtgg cgaggggaaa ttccggactg gtcgatgagc gactgtcgtg
   795241 ccagcgccga tgtttccgcc gcgcgcgcca gccccagcag gcgcaggaag ccgttttcgc
   795301 tgagaacgcg cccatgcgct ccgctctcgc cgtcgaagcg cttttcgatc tccgcctctg
   795361 ttgctctgga gagcagcccc cgcccgaaga ccacgtagtt cgtctggcgc gcgacgccgc
   795421 gcctgaggtg cccgccctgg cgctcgacct cacgcgccgc gagccgccgc ggaaaagcgg
   795481 cgagcgcgcc tatgataccg aatgtcctgc cggcaaccgc catcaggctt tcttcttggc
   795541 cgcgggtttg gccaccacgg acttcgccgt ggcgcgcttc gctccggcgg gcttgacggc
   795601 cggctccttg gctgcggcca catccttggg cttgctcctt gccggaggtt tggattgaga
   795661 aaggctcgct ttcagagcgt ccatcaggtt gacgacgttg ccgcgctcgg gtgcctgcgc
   795721 gatgatcggt ttgtggccct tgagcttctc gcggatcatc tgcatcagcg cgatttcgta
   795781 gcgatcctcg tacttcttcg gatcgaaggt ggtcgccttc tgctcgatga gcgcttccgc
   795841 cagctgcagc atctcgggat ccggttcgcc gaccggtata ttgccgaaat agtccgctgt
   795901 accacgcacc tcattcgggt tgcgcaaggt gcagacgaac atgccggtct cacgcggtcc
   795961 gatggttacc acccgttcgc ggctcgagag aacgagacgg gcgatcgcga gcttcccgct
   796021 tcggcgcaaa gcttcgcgca gcacgacgaa ggtctcctcg gccatcgccc cgtccggcgc
   796081 cagataatag ggcgcgtcct ggtagatcac atcgaccgaa tcgacgtcga cgaaggcttc
   796141 gatgttcatc gtatggttgg attcgatcct gacgctttcc agatccgagt cctcgatgat
   796201 gatgtatttc ttgtcttcgt attcatagcc cttcacgaga tcggagcgct cgacgagtcc
   796261 gagctccgga tcgacaggct tcatgttgat ccggttatgc gtgtccttgt gaagctgatt
   796321 aaaggaaatt cgctcgcttg cgctggtggc gggatagagc ctcaccggac aactcacgag
   796381 actcagtctg agatagcctt tccaacttgc cctgggtgcc atggttttct cctacgcggc
   796441 actgcgataa caactgcgcc agagcgggat gaggaaagtg catgcgattt ccgcctgcat
   796501 cccgcgcctc tacaataacg gcagatccct cgcgaacgca tcgatgtcgg cccagggatc
   796561 gccggacgag gccagaaggc ccggcagcga agaatagttc aaatcctgcg gggcgtcgat
   796621 agcctcaaga tcggcccagc tgagcggcgt cgacgcgggc aaattggtgc gggcccgcag
   796681 tgaataggga gccgcccagg tatggctgcg ggcgttgcgg tgataatcga tgaagatgcg
   796741 cttcacccgg ttgttcttgc ccatggtggt ggtgaagcta tccggagccg tcgccgcgag
   796801 gcggccggcg agcgcactcg tcgccggatg gaatttcttc cagtcgagct tcggcttgac
   796861 cggaaccacg acgtgcactc ccttgccgcc cgatgtcttg acgaagggca cgaggtcgag
   796921 cgcctcgagc tcggacttga tgtggattgc ggcctcgaca acttcccgcc aagcgatgcc
   796981 ttcgccgggg tcgaggtcga agacaacccg gtcgggcttg ccaaggagcc tgcgcgtggc
   797041 tccccagttg tggaattcga cgactccgaa ttgcgccaat gccagatatc ccttcgcgtc
   797101 ctcgacagac agataggtcc tggactcgcc ctcggagttg attgcctcga acgtcgcgac
   797161 cgaaggcggc atgccggtga aggggtggcg ctggaagaaa caatcctgag tccggccgct
   797221 gggacagcgc accagcgaaa ccggacggcc gaggatgtgc ggcagcatga aatcgccgat
   797281 catcgcgtaa tacacggcaa ggtcgagctt ggtcgggccg gacttgccga aaaggcgtcg
   797341 tgtcggattg gtgatcgata tgcttgcgag atccgcgtcc gagatcaggc gctttctcga
   797401 cggggatacc ggcgtcgtca actcgacgtc gcggaggccc ttgaagacgg catggcgcag
   797461 cacattgtca gtcgtccggt tgccgtaatg gatctgagcc ctgagcagcg gccgtaccca
   797521 gatgatttcc ttgggcgctc cttcgagcct tgcggcaccg gagcgcagag gttcgagcct
   797581 ttcaagcaat ttctcaagca tcgctgcgtc gaagccggtt ccgaccttgc cgcgatatgc
   797641 cagctctccg tcggaccact ctccaagggc aagtgccgca agtccctcgg ccgcctgcga
   797701 cacggtgtag ccgacgatca cgaaatcctc cgccttcagt gccttcgtct tcgtccaggt
   797761 cttcgaccgg ccgctccggt aaggcgccga gaggcgtttc gagacgatcc cttccagacc
   797821 catctccgag gcctggtcat aaagcgcgcg cccttcgccg accacgtgat cgctgaactg
   797881 gatggccgag cgatcggtga cctgccccgc aagcagctgc ttcagcagcg ttttacgctt
   797941 ttcgagcggg gcgtcgaaaa gattccagcc gttcaggtgc aggaggtcga aggcgtagaa
   798001 tacgaggctg ttgccggcgc cggtggaaag cgcatcctgc aaaagggcga accggctgac
   798061 ccccgtctcg tccagaacca cgatctcgcc gtctatgatg gcatcgcggc acggcagccg
   798121 ccggaaggcc tccggcaggt ctccgtaacg cttggtccag tccagcccgc cgcgggtgat
   798181 gaggcggacc cttccgtcag cgaggtgggc catggtgcga tagccgtcga acttgatttc
   798241 gtgcagccat acctcgggct tcttaccttt ctcggcttcg ggaggaagga ccgtcggggt
   798301 ggcaagctgg ggctccacgc gatggggcgc tgcgccctcg accgcaccgg gaagcgcgcg
   798361 gggattgagc ttgaccggtt tgggcgctgc cttgggcttt tccacgagtt cctcgatccg
   798421 ccggccggac ttgacgcttt ccggacgggc ggcaaggata tcgatcgacg tgtcggcggc
   798481 gaggtcgcgc tccttgaaca ggagccagtt gcgctgatcc tcctctccgg ggcgaggctt
   798541 caggcgggtc agcatccagc cgcctttgag tttctccccc gccagacgga acttgaaggc
   798601 gcccttgcgc aggtcctgtt cgacatcgcc catcggcgcc cagacgccct tgtcccagac
   798661 gatcatcggg ccgccgccat attcgccctc cgggatcacg ccctcgaagt cgatataatc
   798721 gaggggatga tcctccgtcg ctaccgccag ccgcttgtcg gccggattga gcgaaggtcc
   798781 cttcggcacc gcccagcttt tcaggacatc gccgacctcc agcctcaggt cgtaatggtc
   798841 agcggccgcg tggtgcttgt gcacgacaaa gcggttaccg ccgccggaga gattcccggc
   798901 cggctccggc gtttttgaaa aatcccgctt cccgcggtag gcatcgagct tcgatgtcgc
   798961 catgccccca agctatggct tctcatggcc ggctgcaata tcggccgcgg acaccgcttg
   799021 cccacaggtc ggaatgtcag gcgagcctgc ccggattgcc aagtgtcatg tggcggttca
   799081 cgtccttgta aagcaggtag cggaacttgc cggggccacc ggcatagcag gcctgcgggc
   799141 agaaggcccg gagccacata taatcgccgg cttccacttc cacccagtca ttgttgaggc
   799201 ggtacacggc cttgccttcg agcacgtata gcccatgctc catcacatgc gtttccatga
   799261 acggaatgac gccgccgggc tcgaacgtca cgatcgtcac atgcatgtcg tggcgcatgt
   799321 cggaaggatc gacgaagcgg gtcgtggccc agcgcccgtc cgtttccggc atcggcgacg
   799381 gggggatgtc gcgttcgttg gtgacgatcg cttcgggcag gggaatgccc tcgacccgct
   799441 cataggcctt gcggatccag tgaaaccggg tcggcgaacc ggattcgttt ctgaggctcc
   799501 attcgctgcc gggcgggatg aaagcatagc ctccggattg catcagatgc gtttcgccgt
   799561 cgatcgtcag atggaattct ccgtccacca cgaacagtac ggcttcggca cggggatccg
   799621 tctccggccg cttgcttccg ccggatggcc cgacctccat gatatattgc gaaaaggtct
   799681 cggcgaagcc ggagagcggg cgcgacagga cccagagccg tgtgttcgtc cagaagggca
   799741 gatagctcgt cacgatgtcg cgcatcacgc ccttgggaat gatcgcatag gcctccgtga
   799801 agatcgcacg gtcggaaagc aggttggtct gaggagggtg gccgccttcc ggaaaatagt
   799861 agttcttgtg catgtgggtc ctcaacgaaa tgcgcggcga aatggtcttt cgcctttctg
   799921 cccatgactt tacaggcttg atcggcgata cgtccaatat attgttcaac tcgatccaga
   799981 ggaacgatgt atcgatcgga gcatgcgatg gagctgcgtc acctgcgtta tttcgttgcg
   800041 gtagccgatg ccgccagctt cacggcggct gcgaggggtc tcaacatctc gcaaccgccg
   800101 ctcagccagc agatcaggga tctggaagcg gaagtcggca cgcggctctt cgagcgctca
   800161 agccgcaacg ttgagctgac ggaggcgggc gcgaactttc tcgaacatgc ccggatgatt
   800221 ctggggcagg ttgagcatgc tacccatcag gcgcgggcca tcggctccgg gcaggtggga
   800281 acgctgaaca ttgcgaccac cgggtcggtg ctactgggac cgttgtccaa tctgatcgcg
   800341 cgatttcggg atgcatggcc cggcgtcttc gtccgaatcc atgaaatgga tcccgaggcg
   800401 caggaggcgg cgttgctgtc ccatcgcacc gatctcagct tcgttcgcaa gccccgcaat
   800461 cacccgcatc tcgttgcgct tgtcgcctgg caggagaagg tggacgtggc attgcccgag
   800521 caccatcgcc tggcgaattc cgggacgatc gagctcggcg acctccggca ggaaagtttc
   800581 gtgttcctga ggctcgcgga ttcccgcttc gctcgctacc tgcacgattg ctgcgtaacc
   800641 gccggatttg tgcctgacat cacgaatgag gtggtggaat cctattccct caccagcctc
   800701 gtcgccgcag ggctcggcgt ggcactcgtc ccgaattgta tcagtaccct ttctcggccg
   800761 ggcgtcgtct accgcccgct cgccgatccc gcgccggaag cagacgtcca tgtcatcagc
   800821 cggccaaacc ccggccccgt tgtctcagct ttcctggaga cggcgcagag cacggccgtg
   800881 aatcctcgat agtggcggaa aaaatatcgt caaacgcagg tgtttctaat acaaatatag
   800941 aagcatattt taaatatatt aactaattca tttgagttgc tgaacatatc cagcagttat
   801001 acattgatga gcaattcttt ttgtgaccca catatggggc accactcgat cttcgctcga
   801061 gcgggatgag gaagagtgcg tcggttctcc gcccgcatcc gctctaactt attggaacag
   801121 atccgggaga atggcgtcat ggcggcaatc ctgggttcga ccggctacga tatacttcaa
   801181 ggtacggatg aggcagacca tatctgggga ctgcacggtg gcgatacgat cgacgcgggc
   801241 ggcggcgacg atttcgtcga tggcggcgat ttaagcgacg tgttgacgag ttcgagcggc
   801301 tatgaccggc tgcacggcgg cgccggcgat gaccagatcg tcctgaccgg taccggcggg
   801361 gccgtcaccg gaggcctcgg ctttgacagg ttgaccgtgg atatctcgat gctgtccgat
   801421 cagctggtct tcaacggtgt aagcggccac ggcatcatcg gatacgggag cgccgaggaa
   801481 cggcacatct ttttccatga cgtcgaatgg ctcagcatcg tttcaggaag cggcaacgat
   801541 cgcatcgtgg ggacggcggg tcacgacagg atctcgaccg gagtcggcat cgacgtcgtc
   801601 gtggccgggg cgggaaacga cgtcatcacg aatacgggcg gccaggaccg gctcgagggc
   801661 ggcgacggga acgatcgctt cgtgctcgtg ggcaccggca gcaccgtctt cggcggtgct
   801721 ggagacgata cattgacact cgatctggct gcgaccttgg gcgatatcgt gttcaacgcg
   801781 aacaccggcc acgcgattat cgcaagccga acgcctgacg agcgccacgt cttcgcccag
   801841 catagtgaga tcgagcggat tgaagtgatc actggcagcg gaaacgaccg ggtccagggg
   801901 accacctccg gggacgtcat caagacggac gccggagacg acgtggtcga tggcggagcg
   801961 ggcgacgatt cgatcaccga cgggagcggc gccaaccacc tttcaggcgg cgacggctcc
   802021 gacctcatta cgaccacgct ttattccgct tcggtcgacg ggggagcggg cagggattcg
   802081 gtgcgaatcg aggaacgctc acgtatgagc gacgtcgcca ttgacttcgt ttcggggacg
   802141 gcgtcgaccc gcacggtctt tcgcaacatt gaaacggcca gtctcgcact cggagccggc
   802201 aacgacgcgg tgatcacgac ggatttcctt gccatcttcg tagatgccgg cgcgggcgac
   802261 gaccgcctcg taggcggagc ccggagcgat gcgttccacg gcgaggacgt caacgaccgc
   802321 atcgatagcg gcgcgggcaa cgacacgatc acgaccggcc ttggcgatga ccttgcttcc
   802381 ggcggcgacg gcaatgactc gctcgccaat gacggcggca aggatatcct ggatggcggg
   802441 gcgggcgacg actggattgc cgacgccatt cccggcagcg gcagcctggg cgatggatcg
   802501 gtcatgctcg gcggcgacgg aaatgatgca ttcagggctt ctttcacggg agaggtggat
   802561 ggaggggatg ggcgcgactt gctccagttg cgcctcggat cgctctcggc tgcaatcgac
   802621 tttgatgcgg cgcagggagc gatccagacc ggattgacct tcgccaatat cgaggacttc
   802681 acggtaacga ccggagttgc gaacgatgtg ctccggggtg gagacggtaa cgatgagttc
   802741 gattctctga gcggcaacga ccttctcgaa gggcacggcg gaaacgacat cctgcgcgga
   802801 tattcggatt gggaccggct gttcggcggc gatggcgacg accggctcga gggcggcccg
   802861 catgacgacc ttttgagcgg cggcaacggc accgatacgc tgatcggcgg caccggcgcg
   802921 gacacgtttc tctggtcgga cgaggtcgcc ggccagagcg gcatcgatca catcgtagac
   802981 ttggactttg gcgacgtcat agccttttcc gctgccgctt gtgagaggac cggcattcac
   803041 gaccatgcgg gcttcgttgc cgctgcaacc aacacggccg acggtgtcta tgtcgccttc
   803101 aacggctccg ctgccgacgg catcctgatc gaaaatgctt tgattgcaac tctgaccgcg
   803161 gacgacctgg ttttcggttt cgcttgattc tctgtgaagg gacttaaggg tgccgcgacg
   803221 ccccttcacc ccgcctgcgc ggagaaggtc gcggcagcgg cctgacgaac ttggccgcgg
   803281 acacggactt cgaagcgtgg cgctcaagaa cagccggatg cggcgcgctt cagccctctt
   803341 ccggccggtg cccgccgatc gcgcgtgtca gttcgtcggc cgtgcgacgg acggcggggc
   803401 cgaggacccg tagcctctcg tcgtcgacgc ggacgctggg accggagatc gagatgccgc
   803461 cgatcgcctc gccatattcg ttgaagaggg gggcggcgat gcagcgcatg ccgagcgtat
   803521 gttcttcgtc atcgatcgac cagccgcgaa aacggatctc ctgaacattc ctgatcaggt
   803581 ccggcagcgt ggcaagcgtc cgtccggtga agcatggcag tggcctgccg ttcaaagtct
   803641 tggcgatctc cgtatcggac caggtggaaa gaatcgcctt gccgatgcca gaagcgtgga
   803701 tcggtccccg ccgtcccgga cggaagaagg cgcgcatcgg cgcatgactt tcgacctggg
   803761 agatgaaaac gacgtcgccg tcgtcctcta tgccgatatt tgccgtctcg ccgctttcgt
   803821 ccatgaggcg cttcagaaac gggcggctga tcgtgccgag tttgcgaaag cgcaggaagg
   803881 cgttgccgat ctcgaatgcc ttgacgccga ccgtccatgt cccggtttcg gtatcgttcg
   803941 tcaccattcc gtgctgggcg agcgaggtaa gcagcctatg cacggtcgaa ggcgccatgc
   804001 cggaccgctc cgaaagcgtg gtcaatgtcg agccgtcgcc ttcggcaatg atcgccagca
   804061 gggacaggct cctgtccagc acctgaacgg aggccggcgt cgcattctct cccgccttgc
   804121 gcccccgctt acccttgccg ctcgcatcca tgccagtctc caaatcagtt gagcaatcat
   804181 gctctacagc gattgcatcg gattttctcc attttattga aaatctttat ttccatatga
   804241 tgggaatgat ttccataaac tcgttgaaac ggcgaaacta tggagtagtc ttccacaaaa
   804301 caggaggagt tcccatggcc aagatgcgcg ccgtcgatgc agcagttttc gtactggaga
   804361 aggaagggat cgattgcgcc ttcggcgtgc ccggcgcggc gatcaacccc ttctactcgg
   804421 ccctgagggc acgcggatcg atccgccaca ttctcgctcg ccatgtcgag ggcgcttcgc
   804481 acatggcgga gggctacacc cgcgccaagc acggcaatat cggcgtttgc atcggcacct
   804541 cgggcccggc cggcacggac atgatcaccg gcctctattc ggcctccgcg gattcgatcc
   804601 cgattctctg catcaccggg caagcgccgc gggcgcgcct tgacaaagag gattttcagg
   804661 cggtcgacat cgccaagatc gcagcacctg tcacgaaatg ggcggtcacc gtcatggagc
   804721 cggcgcttgt ccccttcgtc ttccagaagg cgtttcacct gatgcgctcc ggccgcccgg
   804781 ggccggtcct catcgatctg cccgtcgatg tccaactggc cgagatcgaa ttcgatccgg
   804841 aaacctacga gccgcttacc ccctacaagc cggccgccac gcgtgcacag gccgaaaagg
   804901 cgctcgccat gctgaatgcg gcggagcggc cgctgatcgt cgccggtggt ggcatcatca
   804961 atgcggatgc atccgatctc cttaccgaat ttgccgagat caccggcgtt ccggtcgttc
   805021 cgacgctgat gggctggggc gtcatccctg acgaccatcc gctgatggca gggatgtgcg
   805081 gcctgcagac ctcacaccgt tacggcaatg cgaccctgct tgcttccgat ttcgtctttg
   805141 gcataggcaa tcgctgggcc aaccgtcaca ccggcaatgt tccgacctat accgaaggcc
   805201 gcaagttcat ccatgtcgat atcgagccga cgcagatcgg ccgcgtcttt gctcccgatt
   805261 tcgggatcgt ctccgacgca ggtgccgcgc tcaagctctt tctcgacgtc gcgacagaat
   805321 ggaagaccgc cggcaagctg cgcgactggt cgggctgggc cggagaatgc cgcgaacgca
   805381 agcggaccat gctgcgcaaa acccattttg atcagacgcc gctgaaaccc cagcgcgtct
   805441 acgaggagat gaacaaggcc ttcggccgcg acacctgcta cgtctccacg atagggctta
   805501 gccagattgc cggtgcgcag ttcctgcacg tttacaagcc ccgcaactgg atcaattgcg
   805561 gacaggcggg cccgcttggc tggacgctgc cggcggcgct cggcgtaaga gccgctgacc
   805621 cgaaccgacc gatcgtcgca ctttccggcg attacgactt ccagttcctg atcgaggaac
   805681 tcgcggttgg tgcccagcac aagctccctt acctgcatgt cgtcgtgaac aactcctatc
   805741 tcggcctgat ccggcaggcg cagcgtggct tcaacatgga tttcgaggtc agcctcgcct
   805801 ttgaaaacat caatgccgag ggtgatgcgg agaaggggta tggggtcgac catgtggcgg
   805861 ttgccgaagg cctcggctgc aaggccattc gcgtcaggag cccgaatgag ttcgccgacg
   805921 ccttcgacag ggcgcaggct ctgatggaag agcaccaggt gcccgtcgtc atcgaattca
   805981 tcctggagcg cgtcaccaat atcgccatgg gcacggatat caattcggtc gtcgagttcg
   806041 aggaactcgc cgaacgcggc gaggacgcac cgaccgcggt tgccgccctg ctcgattgaa
   806101 gaatgattcc caaagaagga gcgatcgcat gcagagattt gctgcgaacc tgaccatgct
   806161 gttcaacgag gcgccgttcc tcgaccgttt cgcactggcc gccaaggcgg gctttgaagg
   806221 cgtggaatat ctctttccct atgacttcga caagacggcg ctacgcggcg agctcgaccg
   806281 ctatgggctg acgcaagttc tgcataacct gccggcaggc aactgggcgg gcggtgaacg
   806341 cggcatcgct atcctgccgg accggatcga cgaattccgc aagggcgtcg caagcgccat
   806401 cgactatgcg acggcactcg gctgcccaca ggtcaactgc ctcgtcggca tcgcgccgga
   806461 cggcgtgcct gacagcgtgc tgcgcacgac cctcgtcgcc aatctgaagc ttgcagcggt
   806521 cgaactcggc aagtgcggca tccgcctgct gatcgaaccg atcaaccgct tcgacattcc
   806581 cggcttctat ctcaacacgc tcgggcaggc ggcatcgatc atcgaggaag tggggagcga
   806641 caacctcttc attcagtatg acctctacca tcagcagcgc acggaaggcg aactcgtcgg
   806701 gacctataag cgtcaccgcg aaaagatcac gcatattcag ctcgcggata atcccggccg
   806761 caatgagccg ggcaccggcg agatcaacta ccccttcgtc ttcgccgcgc tcgaagctgc
   806821 cgactacgac ggctggatcg gctgcgaata caagccgctg accaccacgg ccgagggcct
   806881 cggctggctc ggtctcgagc gcaagcgcaa acaatccgca gacatcattc aaatcaggag
   806941 ctaagcacga tggcatctat cggttttatc ggactgggta tcatgggcac gccgatggcg
   807001 cgccaccttc aggatgccgg ccacaagatc atcacgtcga aattcgccat cccgccgcgc
   807061 caggagctcg tcgacaacgg gctcgaaatc gtagaaacgc cgaaggctct ggccgagacg
   807121 gtcgacacga tcatcctgat gctgccggat acgccggaag tgaaggatgt cctcttcggc
   807181 gagaatggcg tccatttcgg gctcagcgag ggcaagctgg tcatcgacat gagctccatc
   807241 tcgccgatcg agacgaagga attcgccagg aaagtgcgcg agaccggcgc cgaatacatc
   807301 gatgcgccgg tttccggcgg cgaggttggc gccaagaatg cctccctcag catcatggcc
   807361 ggcggcaagc agagctcctt cgaacgtgcc ctgccgctct tcaagctgat gggcaagaac
   807421 atcacgctcg tcggcgattg cggcgacggc caggtcacga aggtcgcaaa ccagatcatc
   807481 gtggcgctca cgatcgaggc ggtctccgag gcgctcgttt tcgcgtccaa ggcaggggcc
   807541 gatcccgccc gcgtccgcga ggcgctgatg ggaggctttg cctcctcgcg catcctcgaa
   807601 gtgcatggcg accggatgat caagcgcacc ttcgagccgg gcttccgcat ctcactgcac
   807661 cagaaggatc tgaaccttgc tttgcagggg gccaagagcc tcgggatttc actgccgaac
   807721 acggcggcaa cgcaggagct tttcaacaat tgcgccgcca atggcgacag cgggctcgac
   807781 cattccgggc ttgtgcgggc gctcgagcgc atggcgaacc acgaagtcgc ctgatcgaac
   807841 gaagatccgc atgaccggcc gggccatccg tcgcagcggt catgcatccg ggcggcggaa
   807901 ggaggatccg tcgcccggct tttctcaaac gggaggaacc atggccgccg tcgcgaaccc
   807961 gcgtcaattc ctggaaaccc tgttcgcgtc ggccgtttcc gccgccgacc cggagcggac
   808021 catcgccgca aatctgccgg agcggccgaa agggcgcacg gtggtcatcg gagcgggcaa
   808081 gggcgcggct cagatggccc gggccttcga atccgcctgg gacgggccgc tcagcggcgt
   808141 ggtcgtcacg cgctatggct tcggcgcgca ttgcaacaat atcgagatac tcgaagcctc
   808201 gcatcccttg ccggacgagg gtgggctgaa ggcgtcgaag cgcctcctgg cgcaggtcgg
   808261 cagcctgacc gtggacgatc tggtcgtcgc gctgatctgc ggcggcggtt cggcgctcct
   808321 gcctgcaccg ccgcccgggc tttcgctcga ggatgagatc gccgtcaacc gggcgcttct
   808381 ggcgtcaggc gcgccgatca gcgcgatgaa tgcggtgcgc aagcatgttt ccttgatcaa
   808441 gggcggccgc ctggccgctg ccgcccatcc cgccagggtc gtctccctcg tcgtctccga
   808501 tattccgggc gacgatgcgg cgctggtcgc ttccggcccg acgatcgccg acgaagcgag
   808561 ccgagaggaa gccttgaaga tcatcgaacg ttatcgcctc gcactgccgg aaaaggtcat
   808621 gcactggctc gccagcgaag cggcggatgc gccagggcct tccgacccgc gctttgcgcg
   808681 aaacgaggtg cgcctgatcg cttccgccag cgtctcgctc gaggcagcgg cggccaaggc
   808741 ccgggccgcc ggcgtcgagg ccgttattct gtccgacgcg atcgaagggg aagcccgtga
   808801 tgtggggctg gttcacgccg cgatcgcgcg cgagacggcg atgcgcgacc gacccttttc
   808861 aagacccgtc gtgctccttt cgggaggcga aacgacagta accgtccgtg gcgaaggccg
   808921 cggcgggcgc aacagcgagt tcctgttgtc tctggcgctc ggcatagatg gcatcggcgg
   808981 catttcggcg ctcgccgcgg ataccgacgg catagacggc tcggaagaca atgcgggagc
   809041 cttcgccgac cacacgacga tcgcacgcct gctggcgcaa cgcctcgacg ccgctgcact
   809101 gcttcagggc aacgacagct gggccgcctt cgacgccctt ggcgaccttt tcaagccggg
   809161 accgaccggc acgaatgtca atgatttcag ggcggtgctg atccagtgaa cggtgccgcc
   809221 gccaaaaagc aattggtcca ccagggagga aagaccatga tacctctacc gatccgtccg
   809281 cttgcgcata gcgcgttcgc gcccttcggc gatattatcg agccagatga cgccaagagc
   809341 tttccgatca acgccggcaa gtgcattcgc tatcacgacc tcgcgaaggt ggaaaccagc
   809401 gggccggagg ctcgaacgct ggtcagcctt ctgcgtggcg agccctacga gatcccgttg
   809461 gcgttgaaga tggtggagcg gcacccgctc ggaagccagg ctttcatccc tttgacggag
   809521 aaccccttcc tcgtcgtcgt tgctccggac gagggcggcc agccaggcga gccgatcgcc
   809581 ttcgagaccg cgcccggtca gggcgtcaac atcgcgcaga atgtctggca cggcatcttg
   809641 acgccgctcc gttcgacttc cgaatttgtc gtcatcgacc gcggaggcag cggatgcaat
   809701 ctcgaggaac acttcttcga caagccctat caggtcgaat acgcttgact gacacgcgcc
   809761 ccgcacttgt tgcggggcgg ccaagctctt aggttcaggg cttccgagtc cgtgatcttt
   809821 gagcaatgca gcaattcgcc agaaaaatgt ggggagaaac cggttggggc atgccgactt
   809881 cgctcgccct gcacctggcg ctcgccttgc tgttgcttgt gcgactacct gaattgtctg
   809941 ctccggcaaa ggagcaaagc gtcagcgtcg agctcgtccc aacgccgaag aacgagaaaa
   810001 agcccgagca aaagccaacc aagcaaaagt cggacgaggc gagaaaccag cgggcgcgcg
   810061 cccaaccgca gtccttcgag tccgcggcag cgccgacaga gaaggaaaag ccgcctgagc
   810121 ccgacttgcc tccggccgct ccgaagaaga cagaaacgcc aagcgtgagg ccggaggctt
   810181 cgcggcccgc cccggcaaaa ccggagaatg ccgccaatga aagaccggcc gaaaaaagga
   810241 cggcgcttgc ggaactccgg gtcgactcca ctggcgcggc gaacaaggca gccgatgctg
   810301 cggccgcgcc gcccgccgcg cccattccgc aggaaaagcc cgttttcgag gaagcaaggg
   810361 cggagccgac gcagaacccc gccgaggcga gcgccgagcg cgagtcgagc cagctcgtgc
   810421 aggccaagga gctttattcc aaaaacgcct tgtcggatcc acacgtaaaa caggcgatcg
   810481 gcaggttgcc gccgaagaag cggatcgtgc agctctgcac gatcgaggca ttggagcaga
   810541 tacgtcacca aagacccgga gcgatccccg atatgttcgg gcggcctgac ggcggctttg
   810601 cttcggaaac cgcccttaaa gccgatggcg cagtcttccg cagccaaggg aagtggtact
   810661 ccttcgactt cacatgcgag gtcaacccgg aagcgacatc ggtcacttcc ttcagcttcg
   810721 caatcggcaa ggcgattccg aagagcgagt ggggtgcaag acagttgccg agcaattaga
   810781 tcgtgccgca tcggacttat ggtgatggca gctctcttct cgatcttcat tcctgtgacg
   810841 agcacaggaa tgaaggtgaa ggtgggctgg gcatcccata tgctagcggc gcgtccgcgg
   810901 aggcatctgt gcagccgcgg aattggtaag gaaggcgaga tgtcattgcc gaaccacagc
   810961 tcaagaggcg cttccaagcg aatggaggga agaaaatggc aagcgggtat cgctggttga
   811021 acgagccggc aagctggaag gggggcgacc gcgatctgtc gctcaagacc gatggcaata
   811081 cggatttctg gcgggaaacc ttttacggct tcgtgcgcga cagcgggcat gcctatcttc
   811141 gtccggtttc cggcgatttc acagcatcgg cgacgatcat cggtcgatat gagcagctct
   811201 acgatcaggc cggtttgatg ctgcggctca atgagcgcga gtggatcaaa tgcggcatcg
   811261 aatataccga cgggctgatg catttcagcg tggtcgtgac gcgcggcgta tcggactggt
   811321 cggtcattcc attgctcgac aaggtgccct cggatccgct ggaagtgcgg ttgacgcgcc
   811381 atggggatgc ggtgcgggtg cagtttcgct tcggtgagga gcgctggcag atggcacggc
   811441 tctgcccctt ctcggcatcg gatgcggaag tcggggtcac cgcctgctcg ccggagcggg
   811501 caggctttga ggcgagattc cgcgaggtgc gtgtcgggcc gcctattgcg cgtgccttgc
   811561 acgacggatg aaacggcgtc gacgtcggaa agcttcggcg gaaacgtcag gcgatcgcgc
   811621 gctgcgccag gctgaccggc cggcaggagt cgcgtattac gagccgtccc tggagcacga
   811681 gccgacgcgg cgtttcagtg ctggcgccgg aaaggcggtc gagaacaagc tgtgcggcct
   811741 gttcgccgat cgcctggacc ggctgggcaa tcgtcgtcag atgaggttgg aagacgtccg
   811801 cccaggggaa atcgtcgaag cttgcgactg aaacgtcatc cgggcagcga aggccgatgt
   811861 cccggatcgc cttcatcacg ccgatgacca tcaggttgtt ggcggaaaaa atccccgtcg
   811921 gacgctcggg gctcgtaagc agctggatcg ctgcggtgta ggcatccttc tcccggaaat
   811981 tgccgatccg gatcaggctc tcttcgaagg ggagccccgc cgcttccaac gcggccctgt
   812041 aaccggacag gcgctcccgt ccggtcgatg tatcgagcgc tccggaaata tagccgatgc
   812101 gccgatgacc caggccgagc atgtaacgcg tagcgtcctg gaccgcacgg cgattgtcga
   812161 gcacgaccgc atccgtgtcg atcccgtcgc aaagcctgtc gatcagtacc gtcggaaggc
   812221 tggcggcggc gatcatgcgc ttcagggtct cgtcgtcgcc ggcgggcgcg atgatcaggc
   812281 cgtcgacgct ccggtcgatc aacagcgcga tctgctcgtc ctgcaggatc acgtcctcat
   812341 cgctgcagca gagcatcaca gcgtagccgg cccgatgcag cacctcctgg atgaccgcca
   812401 cgacatcggt gaaaaacgga ttggtgatat cggcaaccat gaggccgacg gtgcgcgtcg
   812461 tgccgagctt gagactgcgg gcgatcgcgt tgcgtttgta gccgatctgg ccgatggcct
   812521 gctcgatgcg gctgcgcaat tcaggactga cgggggccga actgttgatt accgccgaga
   812581 ccgtcgccac agaaaccccg gcgactttgg cgacatcgag catcgtcggt gcactggatt
   812641 ttcgtgaact tcgtcgttct cgcattgtgt tcgaaacgtt ttgctgaatt gcttttcgga
   812701 actgtattcg aattgctgta aataggcaat aaaggaagta ttgtgccgct tgacagcctc
   812761 gaaacgttta gattaggctg aagaagatct agcaaatgaa gcgtcagatg tcggtggtag
   812821 ggaggctgcc aatatcatgc gcgatgctgt tccgaccttg ctgggagatt cggtcactac
   812881 agaacccgcg cggccgattt tagcggctga ggcggtctct aagtcgttcg gaggcgtagc
   812941 ggcgctcaag gatgtccgct tcgaccttcg ctccggcgaa attcatgcgc tcatgggcga
   813001 aaacggcgcc ggcaagtcga cgctgatgaa ggtcctctcc ggcgtctacg ccgattacga
   813061 gggcactgtc cgcgtcgacg gagaaatcgc ccgcttttcc agcgttcgcg acgccgaagc
   813121 tgccgggatc gccatcatcc atcaggaact caacctcgtc ccggaacttg gggtcgccga
   813181 caacatcttt cttggtcgcg agcgcgtggt tgccggcctc ttcgtggacc gcaaggcaag
   813241 cctcgaggcc gcgcgcgggc tgttaaatcg cctcggcatc gaactcgatc cggaggcgcg
   813301 ggtcgggcaa ttgcgggtcg gcgaacaaca gctggtcgaa atcgccaagg ccctgtccgt
   813361 ggaagcgcgc attctgatca tggatgagcc gacatcggcg ctttcgtccg gcgagtgtcg
   813421 gcgcctcttc aagatcgtgc ggcagctcgc ggccgatggc gtcggcatcg tctacatttc
   813481 tcaccggatc gacgaggtga tgcagctcag cgatcgggtg acggtctttc gcgatggccg
   813541 gcacgtctgg acccgcccca tggccggact ggacgaggat acgatcatcg ccgcaatggt
   813601 gggccgcaac ctcctggatg cgcatccggt gaaccggccc aagggtgcag agccggtctt
   813661 gtcggtcagt ggcctgtcgc ttgccgtagc tggacgtcat ggctggcgcg acgtgctgaa
   813721 gggtgtgagt ttcgacgttc atgccggcga aatcctcggt atcggcggct tgctcggagc
   813781 gggtcgcacg gaaatattgg agacggtctt tgcttcgaat gacggtgtgc gcggtggcga
   813841 aatccggttg gacggcatag ccgtcgatat acgttcacca cgcgatgcgc gccgtctggg
   813901 ctttgctctg gtgacggagg accgcaaggc aaagggactg catctccagg aatcgatcag
   813961 agacaacgtg gccctgccgc ttgtcggtag gcttgcacga tttggtctgc ggtccttcga
   814021 gcgcgagcgg gcgctcgcga gcagggcggt cgaagcgctc ggcgtgcgtt gcgcgggcac
   814081 cgatcagacg gccggaacat tgtccggcgg caaccagcag aaggttgtca tcggcaaatg
   814141 gctggcgacc ggtccgcgcg ttctgcttct cgacgaaccg acgcgaggca tcgacgtcgg
   814201 tgcaaaacgc gagatctacg atctcgtctt caagctcgcc gccgacggcc ttgcgatcgt
   814261 cgtggtcagc tccgaattgc cggagctcct gctcctcgcc gaccgcattc tggtgatggc
   814321 cgagggccgc cagaccggac tcatctcacg ggaggaggcg agcgaggagc gaatcatgca
   814381 gctcgctgct ccgcggagca cgtttggaag gtcggttgca tgacgtttct gaaggctctc
   814441 tcccgcacga aactctattg ggggctgatc gccattttcc tgatcggggt cctgttctcg
   814501 ccggtgactt cgtcaggcag gaacatcttt ctctcctccg gcaatctcct cgacgtcctt
   814561 cggcaggtat cgaccaccgg gctgatcgcc accggcatga ccgcggtcat tctgaccggc
   814621 ggcatcgacc tttcggtcgg ctcgctgatg gcgatctgca cggtggtctg tgcgatgctg
   814681 ctgaccgtcc ccggcgacac ggcagccatc tatctggggc tgccggccgt cgggcttgcc
   814741 gtcctaatcc tcggtgcggc ggtcgcccgc ttcatcttcc tcaatatcga gaagtcgcga
   814801 tccggcgagg cgcatatccg ggatatcaag cttggcgggg cgcgcggtac cgtccttccc
   814861 gccatagcag gcgtcgtcct ctgtgcactc gtcttgagct tcctcttgcc tcagatgcag
   814921 acgaaattcg gcgtgttcgg cgttctgctc gtggcgccgg cggtggggct gctgttcggc
   814981 gccgtcaacg gcgttatcat cgtggccgga cgattgcagc ccttcatcgt cacacttgcc
   815041 atgatggtaa cggcgctcgg cattgcccgg ctcactgccg gacagaacaa cgccgtcctg
   815101 ccggtctata ccggcagcaa tgccacggcc gacttcgacg tgctgcggca gctcttattc
   815161 ggcatcgtgc cgatgcccgg catattcttc atcgtcgcga ttcttctcta cggcgcggtg
   815221 ctgcgcttca cgcccttcgg ccgctacgtc tatgcgatcg gcggaaacga ggaggcggcg
   815281 cgcctctccg gcatcaatgc cggccgggtg aagatcgtca cctatgcggt ctcgggcctt
   815341 ctcgcgggca tcgccgcggt gctctatgtg gcgcagtacc gccagggcaa gccggatgcg
   815401 ggcgcggggc tcgaactgga tgcgatcgct gcagtggtca ttggcggaac aagtctgatg
   815461 ggagggcgcg ggagccttgc cggaacgttc tgcggggtcc tgatcttcgg tctgctctcc
   815521 aacatcctgc agcttcacaa catcaattcc aatcttcagc tggtactgaa aggcgtcatc
   815581 atcatcggca ccgtgctcgt tcaggagcgc aatgcctacg atcttttcgc gcagttgcgg
   815641 ctgccgggcg caagccggcg gccggttcag ggagacacgt ccgtggagga gcggacgtcg
   815701 agagagacct tgtctctaac aatgggagga aagaaagaat gaaacgccgt gatatcatga
   815761 aattggcggc tgtcgccgcc gttctcgccg cgacgaccgc gctcatgccg gcgggcgacg
   815821 ccgtggccca ggacaagaaa ttccgtatcg gcttcagcca ggcgacgacg atcgagccgt
   815881 ggcgggcgca gttcaacaag gacatcatcg ccgaagcggc aaagcatccg gatgtcgagc
   815941 tcatcataac cgatggtgag gacaggacgg agaagcaggt ggcggatgta gagaacctca
   816001 tccgccagga ggtcgacgca ctgctcgtat caccgaagga atccgcaggg ctgacgggcg
   816061 tggtgcagca ggcgatcgac gccaagatcc cggtcttcgt tctcgaccgc aatgtcgaaa
   816121 ccgaccagta cactcagttc gtcggcggcg acaacaaact gatcggccgg gcggccggcg
   816181 aatatgcggt ggagcttctg ggcggcaagg gcaaggcgca aggcaacatc gtcgagatat
   816241 ggggcggcat gggcacgcag cccgcgcacg accgccacga cggcttccac gaattcaccg
   816301 acaaggagcc gggcatcaag aacctgctcg acaagcagtc gggcgattgg aagcaggacc
   816361 aggcctacaa catcatggcg acggcgctgc gcaacaacga gaaaatcgat ctcgtctacg
   816421 gccataacga cccgatggcc tacggcgctt acctggcagc gaaggacgcg ggccgcgaga
   816481 aggaaatcaa gttcatcggc atcgatgcct tgccgaacga gggcgtgacc tgggtcagca
   816541 atggagaact gaccgcgacc ttcctttatg cgacgccggg ggccgaggga ctgcgccagg
   816601 ccgtgaagtt cctcaagggg gaaaaggtcg aaaagaccgt cacgctcgac acgctgaagg
   816661 tgacggagga aaacgccgcc cagatcatga aggacaacgg cctgtaacag ccgcggagcc
   816721 aggtgtgtcc agacgcgccg cggcaatgcg aagtctgcgt gcatttcttc gcatcggttc
   816781 cgatctgagg gggcatgcag cggggcgggc ggcggatacg agggggaccg cccgcctttt
   816841 tctttttcgg accgtttccc tgattcagcc atagactgag gcgctttacc gcatcatcga
   816901 gagcgccgtg gcgaagaaat cctcgccgcc gaaattgccg gatttcagcg ccagcaacat
   816961 gtcgtttccg gcagagccga tcgtcctcaa cagaggaaca ccgggggcga tctccgggcc
   817021 gatcaggaag gctggaatgg cgagcctgtc gacggtggcg ccggaggttt ctccgcctgc
   817081 gacgacgagg cgtctcacgc cgcgctcgac gagctcgccg gcgatcgctg cggtggccgt
   817141 ttcgatcgcg tgcccggatg cttcgcgccc gtagcgggcc tgcagacgcg aaacgacgtc
   817201 cggcgcggcg ctggcggcga tggcaacggg gccatcggca atccgctctc cggcccaggc
   817261 gatggcggcg gaaatgtcgt cctgtccggc caggagtttt tccgtatcga gcctcagcac
   817321 tggcatatgg cgttcggccg cttcgagctg cttcagcgtt gccaccgaac aactgccggc
   817381 aaggaccgcc gcgaggccgc cgaccgggag acggatcgcg tcgttcgccc ctgtattcgc
   817441 cgatgcccgg ccggagctta caagcgcgcg tgcaagaccg agaccgaggc ccgatgctcc
   817501 ggtggagacg ggcatttcca gcgcgacgcg accaagcgtt tcgagatcgc gttcgaagac
   817561 cgcgtccgcg atcgctgcag cgacgccttc gccgcgcaag gcgccgagcc gcgccttcac
   817621 cgcatcggtt ccggccgcca ccgccggcag atcgacgagg ccactcctgt tgcgcgactg
   817681 gcgcgcgagc acgcgtacca gattggcatc acccatcggg ttgaggggat ggtctttcag
   817741 cgggctttcg tcgagcggtt ggccgttgac gaaaagatgg ccgagataga cggtccggcc
   817801 cgtttccgga aaggccggcg taacaagggc gatgtcgccg gacgagacgc tcagaagcgc
   817861 ttcggtcacc ggtccgatat tgccgagatc cgtcgaatcg aaggtggagc agattttgta
   817921 gagcacatgg atggcgcccc gcccacgcag ccagctttcg gccttgagcg cggcggccac
   817981 ggcctcttcg gctgcgaccg aacggatctt gagagaaacc accacggcat cgacatccgg
   818041 aagtgcgagc gagggatccg gaatgccgac cgtctggacg gtgcgaagcc cattcttcgt
   818101 cagcgtgttg gcgaggtctg aagcgcccgt atagtcatcg gcaatcgagc cgagcaggat
   818161 tgtcatcggt cagctccgtc gaaaggggtt gaaccaggca aggccgtcca gcgtggagcc
   818221 gcgcgggaaa tattcgcagc cgacatgtcc gtcatagccg agccggtcga tttcctcgaa
   818281 caggtacgaa tagttcaact cctcgccatc aggctcgtgc cgcgatggca cgctggcaat
   818341 ctggatatgc ccggtaaccg gcagcaggtg ccgaagagcc attgccacat cgccatgcat
   818401 gatctgccgg tgatagacgt cgaactggag cttcaggttc gggagcgcga gttcggcgat
   818461 gagccgctcg gccttagcga aatcgtcgag aaaatagccc ggcatgttgc ggccgttgat
   818521 cggctcgatc aggagatcga tgctcttttc cgccaggcgc ccggcggtgt aggcgatgga
   818581 gcggcggtag caggatgccg cttcgggatc ggacggatcg gaaagacccg ccatcaggtg
   818641 cagccgtttt gcgccggttg cggccgcgta gtagagggcc ttgtccacgc ctgatttcaa
   818701 ttcgtcgaag cgtccgggca aggctgcgat cccgcgttcg cccgccaccc agtcgccggg
   818761 aggcagattg aacagcgcct gctccagcct gttacggata agcctctcgg cgatcgcctc
   818821 cggcggtacc tcgtaaggga agaggtactc gacggcagtg aatccggctt ccgcggcggc
   818881 gtcgaagcgg tcgagaaatg tccactcgtt gaacatcatt gtgagatttg cggcaaaaac
   818941 aggcattcgc ggcgtcctta tggcttatcc ttgcccggca actgggctcc ggagagttgt
   819001 gcgtagagcc gcgccagggt ggaatcgtcg tcgcgtccca ttcccgctcc cgaggcggca
   819061 agatacatct gcagagcggc ggctacgagc ggcaccggat agcgttcggc gcgcgccatg
   819121 tcctgaacga tgccgagatc cttcacgaaa atctcgacgg cgctcagtgg cgtatagtct
   819181 ccggccaaca catgcgggat gcggttctga aacatccagg aattgccggc cgatgcggtg
   819241 atcacctcat agaccttgtc gaggtcgagg ccctgtttgg ccgcaaaggc gatcgcttcg
   819301 caggcggccg cgatgtgcac gccggcgaga agctggttga tcatcttgaa ggcggcgccg
   819361 atcccggcgg cctcgccaag ttcatagacc ttcgcggcca tgcaatcgag ggccgggcgg
   819421 gcggcggcga aggcttgcgg agggcccgag gccatgatcg tcagttcgcc cgtagcagcc
   819481 tttgccgcgc cgcccgatat cggtgcgtcg aggtaatgaa gcccgagcga ttcgatccgc
   819541 ttcgcgaggt cgcgcgcaat cgacggatcc atggtcgcag aggatacaag gacggcacca
   819601 ggcttcattg cgccagcgac gccatccgga ccgaacagaa cggcttcggt ctgcgcgccg
   819661 ctgacgacga cagaaacaac gatgtcggcg cccttcaccg cttcgccagg ggagcccgcg
   819721 ccgtggccac cttccgcgac gaaacgctcc actgccgccg gtgcgacgtc gtagcccgaa
   819781 acgtcgagac ctgcgcgcgt catcgagcgc gccatgccga aacccatcga gccgaggccg
   819841 agcactgcga tcttcgatgc cattttcgat tcctccatcc gatgcgggct ccttctaaag
   819901 cgttttggca gcgctgccaa ctaaaatggt agcgctgcca aaaatctccg cctatgaagt
   819961 gtgctggtct tccggagctt cgacgctctt ttgactgtgg agcctgcgaa cgtggtgatc
   820021 gacttcaagc aacggacgac tgtgacgctc gccgaggtgg ctgccgctgc cggcgtgggg
   820081 gagagcacgg tgtctcgcgt tctccgcaat catggatcct tctcgccgaa agcgcgcgag
   820141 cgcgttctcg atgcggtcga gcggctcggc tatgtgccga acaggatcgc cgggaccttg
   820201 gcatcggccg ggtcgcgcct cgttgccttc gtcattccgt ctctcaccaa catcgtgttc
   820261 cccgacgtgc tgcgcggcgc gggcggcgtc ctggaggaga atcactatca ggcggtgttc
   820321 tcggttaccg actacgattc ggagcgggag gaaacgctcg tctccgccat gctcgcctgg
   820381 cgcccgaccg cggtgatgct tgccggtttc gaacataccg aaggcacgct caaaatactg
   820441 cgggcaagcg gctgcagggt cgtggaactg ctcgacaccg atggaacggc cgcggatctg
   820501 gccgtcggtt tctcgaaccg gcaagcgggg cgcgcaagcg ccgagtttct gttgcggcgt
   820561 ggctaccgcc ggctcggcta tgtcggccac gatctcgatc tcgacacacg cgccggcaaa
   820621 cgcttcacgg gcttctgcga agctctcaac cttgccggat cgcgcctcgc cggccgtgaa
   820681 atccgcgcgg gtgcttcgtc ggtcgagagt gggcgcgcgg gactaaagca gctactcgaa
   820741 agggctccgg ggctcgatgc ggtctatttc tcgaacgacg acatggctct cgggggatac
   820801 ttccactgtc tgtccaacgg cattgccgtt cccgccgacc tcgcgctttt cggccataac
   820861 ggactggata tcggccaagc tatacctcag cctctggcga gtatccgcac gccgcgcgtc
   820921 gccaccggaa agctcgcggc cgagttggtc atcaacgaag caccgcccca ggtcgccgat
   820981 ctcggatttg aactgatcga aggtgcaaca gcctgaacga aagggcctcc aatgtccgat
   821041 acacgtcttc gcgaggaaat ctgccgctac ggccgctccc tcttcgaaag gggcctgacg
   821101 cccggctctt ccggcaacat atcgatgcga ctcgatgacg gcggctggct ggtgacgccc
   821161 accaatgcgt cactcggctt cctcgacccc gggcgcattt cgcggctgga cgccggcggc
   821221 cggctcgtct cgggtgacaa gccgacgaag gagatcccgc tccattccgc cctctatgag
   821281 tcgcgtggca gcgcccgcgc gatcgtgcac ctccattcga cgcacgcggt cgcgctgacg
   821341 atgctgcccg agatcgatcc gcgtgccgcg ctcccgccga tgacacccta ttacctcatg
   821401 cgggccggcg agacggcact cgtgccctat taccgcccgg gtgacccggc cgtcgccgat
   821461 gcaatccgcg ggcttgcggg gaaatactcc tccgtactgc tcgccaatca cggccccgtc
   821521 gtcgccggag acagcctcga ggcggcggtc ttcgccacgg aggaactgga ggagacggca
   821581 aagctctacc tgctcctgcg caatcttaat ccgcgctatc ttagccctca gcaggtgctg
   821641 gatctcgcca gcacattcaa gctcgacctg ccgtcgctcg acgatcatga gggacatgat
   821701 catggataat ctgcctccga gcgtctttct cgaacggcag ccccctcatc gggtttaaca
   821761 aggtctaacc cctctccccg taacaagaaa ggggctagtc gagcgagtcc gatctcacgg
   821821 cgccgcacaa cgcgagcttg catttttggt gcgctgccgc aacgaacgtc acttgaccgc
   821881 ggcttccgat acgcagtcta ttcgtgatac tgatctggtg gaccaaccag tgggtcagtg
   821941 gaggcggcag tgatcggaag tccaatcctc acgcaaatgc cgaaggtcgg gcggagcctc
   822001 gagcgccgaa ctgcgcgtga gcttatcgcc gacaagctga tggtgctggt cgcgaccaac
   822061 atgctgaggc ctggtgacgt tttacccggt gagcgcgagc ttgcgaatgt gctccatgtg
   822121 agccgcgaga cggttcgcgg cgcgatccag acgctggcgg cgcgcggtgt cgtcgaggtg
   822181 tcgcaaggga gccggacgcg tgtcggcaat atcgatctca gccatctcac cgtgacgatc
   822241 gcctcgccga gcgcaatcga tagttatgat atcgaggatg tccacgccgc aaggctccat
   822301 atagagttga aagtggtcgg cgatgcggcc gaaaatatag atgaggaaac gctgggaaag
   822361 ctgggcgccc ttctcgatgc gcagaagctc tgcagcgacg acgcaatgcg ctttcttata
   822421 tgcgacagag agttccatgt ggcgatttac cgggcttgcg gcaatccgct gctctccgat
   822481 tttgtcacag acctttacac ctatatgatg gaccaccggc gcagcgccat gtcacggccg
   822541 ggcgccatcg acgccagcta caaggaccac agcgacatcg tcgccgcttt gcggcggcgc
   822601 gaccgggcgg ccgtcgtcgc cgcctttcac catcatctga tccgcattta cgatacgacg
   822661 aagaccctcc ttgccaacga ggaggcttcc ggcgggaaac cgaagcaaaa agcaccggca
   822721 ggtcagggct gatcggagtg actcaacagg gggaggttag ccgcagatgc atgtaatggt
   822781 cataggtgca gctggcatga tcggtcggaa gctggtcgaa aggttagccg aggagcccgt
   822841 ttcccttggc cgcgagattg cgagactgac gctggtggat gtggtggagc cgcccgcgcc
   822901 gccggtgttt tcaacgattt cgacgccgct ttctgtcgac ctctccgacg agggcagcgc
   822961 cgagcggctg gtctcatcga ggcctgacgt tatcttccac cttgccgcta tcgtttccgg
   823021 agaggcggag gcggacttcg acaagggtta tagggtcaat ctcgacggca cgcgcgcgct
   823081 cttcgaggcg atccgccgtg aggggcagcg cgagcgctat gtgccgcgcg tcctcttcgc
   823141 ctcctcgatc gccgtctttg gccagccgtt cccggaaaag atcgacgatg cgttcttcac
   823201 gacgccgttg accagctatg gaacgcagaa ggcgatctgc gagctgctgc tcgcagatta
   823261 cacccggcgg ggtttcttcg acggcatcgg tattcggctg ccgaccatct gcattcggcc
   823321 cggaaaaccg aacaaggccg catccggctt cttttccaat atcttgcgag agccgctctc
   823381 cggccaggag gctgtcctgc cggtggagga aaacgtccgc cattggttcg cgagcccgcg
   823441 ctcggcggtg ggtttcttta ttcatgccgc gcgaatggat acaagtatca tcgggccgcg
   823501 gcgcaacctc accatgccgg gcctctcggc actggtcggc gaagaaatcg aagcgcttgg
   823561 ccgtatcgcg ggccagaagg cggtgagcct catccggcgc gagccggatc cggtcatacg
   823621 ggaaatcgtc tccggctggg cgaccgattt cgatgcccgc cgtgcgcgcg agctcggctt
   823681 cacggcagag agcaatttcg acgagatcat ccgcatccat atcgaagacg aactcggagg
   823741 gagaatctga gatggcgcag gcgaatggct cgggtgacgg caagatcgca ctggtcacgg
   823801 gcggcggcac cggtgtcggc cgcggcattg ccgaggcctt gagcgccgag ggctacagca
   823861 tcgtcgtcac cggccgccgc ccggatgtgc tcgatgccgc ggccgccgaa atcgcggggc
   823921 gaaccggcgg taccgtccgc gcgatcgtct gcgatgtcgg caatccggat caggtcgcgg
   823981 acctcttcgc agccgtccgg acggaattcg gccggctgga cctgctcgtc aacaatgccg
   824041 gctcgaacgt accccccgtg cctctcgaag aggtgacctt caaacagtgg aacggcatcg
   824101 tcgccgcgaa cctgacgggg gcctttctct gcacccaaca cgcctttcgg ctgatgaaga
   824161 cgcaaacccc gcgcggagga cggatcatca acaacggctc gatctctgcg cagacgcccc
   824221 ggcccaactc ggcgccctat accgcgacca aacacgccat taccggcctc accaagtcga
   824281 cggcgctcga tggccggatg cacgacgtcg cctgcggcca gatcgacata ggcaatgccg
   824341 ccaccgacat gaccgcaaga atgagcaccg gcgtgctgca ggccaatggc gaagtcgcag
   824401 cggagccgac gattccgatc gggcacattg ccgatgcagt cgtctacatg gcgagcctgc
   824461 cgctctcggc caatgttctc acgatgacgg taatggcaac caagatgccg ctggtcggcc
   824521 gcggataaaa agaggttttc ggccgggcgc aaccgcacaa acataaaatg ggactgcgca
   824581 agcgcagaga ccggttctgg gaggaacgaa aatggcaggc gtggattttg tcgatgtccg
   824641 gaagtccttt ggtgcttttc ccgtcatcaa gggcgtgaac atcgagatcg aggatggcga
   824701 gttcgtcatt ctcgttgggc cttccggttg cggcaaatcc actttgctcc ggatgctggc
   824761 gggtctcgaa aacatcaccg cgggcgagat ccgcatcggc gaccgggtcg tcaaccggct
   824821 gccgccgaag gaccgcgaca tcgccatggt gttccagaac tatgcgctct atccgcatat
   824881 gacggtcgcc gacaatatgg ctttctcctt gatgctggct tcgaggccga aatcggaaat
   824941 cgaaaagcgc gtcggggttg ccgccgaaat cctcggcctg tcgaagctgc tcgaccgtta
   825001 tccgcgccag ctctccggcg gccagcgcca gcgggtcgcc atggggcggg cgatcgtgcg
   825061 tgatccgcag gtattcctat tcgacgaacc gctatccaac ctcgatgcga agctgcgcgt
   825121 cgccatgcgt gctgaaatca aggaattgca tcagcggctg aagaccacga ccgtctacgt
   825181 gacgcacgac cagatcgaag caatgaccat ggctgacaag attgttgtca tgcatgacgg
   825241 tatcgtcgag cagatcggcg ccccgctgga tctctacgac aatcccgcca atctcttcgt
   825301 tgccggcttt ataggatcgc ctgcgatgaa catgatcaag ggccgcctcg atccggataa
   825361 tccgcgtgcc ttcctcaccg cggacggaac cgccctgccg gtggcgcgag ctgcggcaag
   825421 cgcacatggc cgcgatctcg tatacggctt gaggccggaa tatatgtccc tcgatccgaa
   825481 tgggctgccg gccgaaatcg ccgttatcga gccgacgggt tacgagacgc agctgatcgc
   825541 aaggctcggc ggacatgatg tgacctgtgt attccgcgag agagtgatcg ccaagcccgg
   825601 ggaaaccatc cacctcgcga tcgatgcggc gcatgtgcat ctgttcgacg ccgcaactgg
   825661 gcggcggctg gtcgactgac gccctggctg ccgacctgaa agccgcattc gccaagcggg
   825721 acggtgaatg ccggatcaag aagctcccgc ttttcgagga ggagtagcat gccgataaag
   825781 agacgtgatt ttctcgcaac ctccgccgca ctcgccggcg ttgcgggtct gggcatccgc
   825841 ccgtccttcg cgcaggccga gccgagctac aagccggagg agggcgcgag cctcaggctt
   825901 ctcagatgga cgcctttcgt caagggcgac gaggacgcct ggatcgccaa taccaagaaa
   825961 ttcactgaga cgacgggcgt cgaggtccgc atcgacaagg aaagctggga ggatatcagg
   826021 ccgaaggcgg cggtcgccgc aaatgtcggc tccggtccgg acatggtgat gtgctggttc
   826081 gacgacgcgc atcaatatcc cgacaagctc gtcgacgtga cggagctcgc tgattatctc
   826141 ggcaataaat atggcggatg gtacgacggc ctgaagggct atgccagccg cgaggggcag
   826201 ttcatcgcca tgccgttggc cgcgatcggt aacgccgtct gctaccgcga aagccacatg
   826261 aaggcggccg ggttcagcga gttcccgaaa gacacggccg gcttcctcga gctctgcaag
   826321 gctctcaagg caaagggaac tcccgccggt ttcccgcatg gaaaggccgt cggcgacggc
   826381 aacaactacg ctcattggct gttgtggagt catggcggca agatggtcga cgagagcggc
   826441 aaggtcatga tcaacagccc ggagacgctc gcggcggtca actatgccaa atcgctgtat
   826501 gagacgttca ttccgggcac ggagagctgg ctcgacatca acaacaatcg tgcctttctc
   826561 gccgggcagg tatcgcttac ggcaaacggc gtctcgctct actatgcggc caagaaggac
   826621 cccgcgcttg ccgaacttgc ggctgacatc cgcacgacca acttcccgat cggtccggtc
   826681 ggccagagcg tcgaactgca tcagacgagt tcgatcctgc tcttcaagca cagcaagtat
   826741 ccggaagctg ccaaggcata tctgaagttc atgatggaag ccgaccagat gaacgcctgg
   826801 atcgaggggt caagcgccta ttgctgccag ccgttgaaag cgttcgccga taacccggtc
   826861 tggacctcgg acccgattca cgcgccctat gcgcgggcct cggagacgct gcggccgaac
   826921 ggctatgccg gtccactcgg ctatgcctcg gcgggcgtca tggctgacta cgtactggta
   826981 gacatgttcg caagtgctgt taccggccag gcaacgccgg aggatgcgat cgtcgaggcc
   827041 gaacggcggg cgaaccgcta ctatcgggtc tgatccctgg cggcctaagg gccgcctctc
   827101 gacgccggca gcgagcgctg ccggcggtct ctgaaatcgc gcaaccagca gtccctccag
   827161 ccggagaagc ccgatgtcca taacgccgtc cggaaaacca tccaccacgg cttcgctgat
   827221 gcaaaacaac aatgtgctcg gcttcctttt catgctgccg gcagccgtct tcctgatctg
   827281 cttcctgacc tatccgctcg ggctgggcgt ctggctcgga ttcacggaca cgcgcatcgg
   827341 ccgcgacggg gtctttatcg ggatcgagaa ttacacgttt ctcgcagagg actcagtctt
   827401 ctggctctcg gtttacaaca cgctgctcta caccttcgtg gcgtcgatcc tgaaattcgt
   827461 gctcgggctt tggctggccc tgctgctgaa tgaaaatctg cccttcaagt ccttcttccg
   827521 tgcgatcgtg ctcctgccgt gggtggtgcc gacggtgctc tcggcgcttg ctttctggtg
   827581 gatctacgat tcgcagtttt ccatcatctc ctggtcgctg atgcagctag gcatcatcga
   827641 cgggcctatc aatttcctgg gcgacccgaa caacgcgcgt gcttccgtca tcgcagccaa
   827701 tgtctggcgc ggcattccct ttgtggcgat ctcgcttttg gcaggtctgc agacgatccc
   827761 ggcctcgctg caggaggcag cttcgctcga cggcgccacc agctggcagc gtttccgcta
   827821 tgtcaccctg ccgatgctga caccgatcat cgccgtcgtc atgacgtttt ccgtgctctt
   827881 cacctttacc gattttcagc tgatctatgt gctgaccaag ggcgggccgg tcaatgcgac
   827941 ccatctgatg gcgacgctgt cgtttcagcg cggcattccg ggcgggcagc tcggcgaggg
   828001 ggcggcgatc gccgtcgcca tgatcccctt cctgctcgcc gccatcatgt tcagcttctt
   828061 cggtctgcaa cgccgcaaat ggcagcaggg cggccaggat tgagcgggag gacaatatga
   828121 acgcgaccac acgaaccgag gacgagaccc tcaccgacac cgccgaaggc atgagctatc
   828181 tgaaccgcct gccgcggagg atcgtcgtgc tttacctgcc gatggcggtc ttcgtcttcg
   828241 tattgctgtt tccgttctac tggatggcaa tcacggcggt gaagccgaac tcgcaattga
   828301 ccgactacaa caattacagc cccttctggg tggtcagccc gacactcgac cacatcaagt
   828361 atctgctctt cgagacctcc tatccgggct ggctctggaa cacgatgctg gtggccgtag
   828421 gttcgacgat cctgtcgctt gccgcgtcgg ttttcgcggc ctatgcgatc gagcgggtgc
   828481 gcttcaccgg cgcgcgtccc gtcgggctga tgatctttct cgcctatctg gtgccgccgt
   828541 cgatcctctt cattccactc gccttcatcg tcttcaaatt cggcatttac gattccaagc
   828601 tggcgctgat cttcacctat ccgacgttcc tgataccgtt ctgcacctgg ctgctgatgg
   828661 gatacttccg ctccattccc ttcgaacttg aggaaagcgc gctggtggac ggcgcgacgc
   828721 gctggcagat cctggtcaag atcatcctgc cgctcgccgt tccgggactg atatcggcgg
   828781 gcatcttcgc cttcacgctt tcgtggaacg agttcatcta cgcgctgaca ttcatccagt
   828841 cgtcggaaaa caagaccgta ccggtcggcg tgctgacgga gctggtgcgc ggcgacgttt
   828901 tcgaatgggg cgcgctgatg gcgggcgcac tgttcggctc gctgcccgtg gtcatcctct
   828961 attccttctt cgtcgactat tacgtttcgt cgatgacggg agcagtgaag gagtgagttc
   829021 gcatcagcgc cggacgagga gcagggcaaa agtcgtcagg atcaccacga aaggcgccca
   829081 ggcgccgaaa tcctccatgg ccagaagagt gagtgcgctg aaggcacacc agaggagcgg
   829141 aatcggtaga agcagccaga gcttctggga gaggaacgcc acaagggcgc cgagcgtcac
   829201 cgcagcggtc ggatccggca tcgtcccgaa gctttcggcc gaggcgggtg cgcggcccgc
   829261 aatcagcggc aggaaaggat aagcgagcaa accgaagacc atcaggccga tgccgccgcg
   829321 acgtcgcagg ctgtttgcgg gcaatgctgc gcgatccgtc cataggatcg cgagaagaag
   829381 caaaccggac tgcagcatga aggctgccgt cccataagac attgcccaat ttatcgtgga
   829441 gtagcgcagc cacagaaact gccatgcgca gaagaaccaa gccacagaga gcgtggccat
   829501 ggccgcggcg cgagcgcgcc ggccgtcggt ggcggtggcg aacaggacgg cgagtgcgcc
   829561 tgcgatgaaa acaagctgaa acggccagag tccctgatta tagcgttcga cgagacggaa
   829621 atagacacgc ggagaaaaca tcaggaaatc ggcgagcgta taggttgccc attcggccat
   829681 catcccaagc ccttctcacg ccgcgaaggg atcatgctta tagcgcctcc acataggcgg
   829741 tcatgcgctt gcgcagtttt tcgtccggca gaattcctct cgcggcctcc agattttccc
   829801 ttacatgatc gacgcgagta gtggccggga tagcgcaggt cactgccgga tgggaaataa
   829861 taaacttcag tagaaattgc gcccaactgc gggcccccgt ctccgcgacc caatccggca
   829921 acggcgcatc ttcgaaccgg cggatcagat cgccctgccg gaacggccgg ttgacgatca
   829981 cggcaacgcg cttctcctgt gcgaggggca ggatacgctc ctctaccgcg cgatcgagaa
   830041 tattgtaggt gatctgcacg aaatcgattg gctcgctggc catgacctgc tcgatctcgc
   830101 ggtgtctgcg cccctccgag gtcgtgatgc cgacatagcg cagccggccc gacgccttca
   830161 tgctgaagag cgcgggcaga tgctcgtccc aggagacaag attatgaacc tgcatgagat
   830221 cgaagcgcgc tacgccccag tgttcgcgcg aagcctcgat ctgagcggcg ccaccgcttg
   830281 tgtccgatat ccagaccttc tccgctgaaa agaggcgttc cggataaccg atcctggcga
   830341 ggccgtgacc gatggtcggc tgggaggatc catacatcgg cgagcaatcg atcatccggc
   830401 cgccaccctc gaagaaggca gcgatcacgg cggcgcattc gtccatcagg acggagtcgt
   830461 ctccgacgtt gaaggtgatc caggtgccga ggcccaccag cggcaacgct tctccggtct
   830521 tcggtatgga tcgcgccatg agaccggcgg cctggctcat cgccggccgc gccatgaacg
   830581 gcatagacat gccgattccc agcccccgaa cgactgcgcg ccgcgtgatg gtcatcgccc
   830641 gctcccttca gtttcgaaat tctgaagctt gccggatgat acctcttgcg gcgcgactct
   830701 tccacgcctg caggatgcac gcggctcatc aacggacccg gttcacgatc ctcaatcttc
   830761 cgtccatcag caggccgtcc tccgatcaga gcgtctcgca gccgctgtgg agggcggccg
   830821 ccgcgtcatg gcgccatagg tcgacagttc cacggcaaca ggatctttta gcgcgcgacg
   830881 tttgcgattt cgttcagcac ctgaacgctg atcgttccac cgcggcgatg agttcatcaa
   830941 ccaggtcggc cttggtcgcg tccgaagaaa aaagatagat cagcacgttc gtatcgataa
   831001 agctaccggt catttgcctc atcccggtcg aaccggagaa gggtgatgcg ggcggaagac
   831061 cgtgcgcacc tatcctcatc ccgctctatc tccgatgcgc gctccgggga gccgaggctg
   831121 gctccagctc attgatgccg tcagggtgct gatcattcgc gggaacggcc tcgatctcga
   831181 gattgtgctt tgcatgacgc atgtgctgcc attccttctc caggcgcagg aatacgtccg
   831241 tcggcataaa ttttcgctgc attcgaccct ccaagcggct gcgcaatgaa cacgcgagga
   831301 actgctttgg ttcccgcgcc cttgtaacaa tcgtgaagaa tattcgtttc agtatggcgt
   831361 cgaaccggcg ccgaccgcag cgcgccgcca ataggtgaac ccgcgctgct gctgatcggt
   831421 tatgcggcgg ggtccaccta tcgcccctcg aaactggtga ggccgcctcc tcagtagtat
   831481 ccggcggacg gcctcaaggc atacgcctca agccggattt cactcctgac gcgcgctcgc
   831541 gtcaaggttt agcgcttact caattcgagt tagaaaaggt gtagcggcag ccgtggttcg
   831601 cccggaatag atcgcgattt taggcagagc ccgccaagca tagctatcta aagcgtttgc
   831661 agggtccagg atgccgcgct ggcgatcagc ccaagggcga aggcaatggc gatggcaaat
   831721 ctcaccatct tcatccgacg cgcccgttcg ccggtccagt cgtagctcat catgcgctcc
   831781 gaagacgttg cagctcgaac atgaagattg gacgttcttt cttaacaaaa cgaaaactat
   831841 gcggtcccgc gccgttgggc ctgtccggag cgagagcgag tttgacgcgt ggagttgttg
   831901 ttactgaacg aaccctttac gagaacaatt ttattaaaat aagagcaaat ttaaatcaaa
   831961 gtaaaggcca atattgcgca acattcctgc gcatagatat ttttggcgac ggcaaaacaa
   832021 tttaccatta ttgcaaaaat cgccggcggt taactattca cgccgatgat cagtctatag
   832081 ttgcaggatc attgcgggct tgggagcgat taggcatgtg cggcttcggc ggttatcttg
   832141 gttcaatacg ggacggtaag ccccttctcg aaaggatgac cgccgcgatt ggccatcgcg
   832201 ggccggacga gcatggaatc tttacgaccc cgggcgcggg cctcggccat gtcaggctgt
   832261 ccatcgttgg ccttggcgac ggccagcagc cgatgtccga ttcgagtggc gagctgacga
   832321 tcgccttcaa tggtgagatc ttcaattatg ttgaactgcg tgacgagctg cgcgcaaagg
   832381 gccgccgtct tcgcacgtcg agcgacacgg aggtcatcct ccatctttat aaagagatgg
   832441 gcgaagaatg tctctccctc ctgaacggcg acttcgcctt tgcgatctgg gatgcacgcc
   832501 ggcacaggat ggtgctcgcg cgcgaccgca tgggggtgcg ccctctcttc cacacgatga
   832561 agggcggcac tttctatttc gcatccgagg tcaaggcgct tctcgagatt ccgggcctct
   832621 cggcagagat cgacccgatc gcgcttgatc agatattcac actctgggcg ccgattgcgc
   832681 cgcgtacgcc ctttcgtggc atccacgagc ttgagcccgg ccatctgatg gtcgcccatc
   832741 agagcggcat caccacaagg ccctattggc agctcgatta tccggaccgg gaccagcgct
   832801 ccgcctatac gaacgaaaac caagcggcgg aggaattgcg cgcactcctg acggaggcga
   832861 ctcggatccg catgcgggcc gacgtgccgg tcggcgccta tctttccgga gggctcgatt
   832921 cgtccatcat ctcggcgctg gcggccggga tgacgtccca gggcctgcgc accttctccg
   832981 tcactttcga cactgcggaa catgacgaaa gcgcgtttca ggaggcgatg gcagcggcac
   833041 tcggaaccga acaccgcgct gtggcatgcc gcgccgggga catcgccagg gactttcccg
   833101 atgtcgtccg tttcacggag aagccgatca tccgcaccgc ccccgcgccg ctctacaaat
   833161 tgtcggacct ggtccgcgag acgggtctga aagtggtgct gacgggagag ggcgccgacg
   833221 aggtattcgc cggctacgac attttcaagg aagcgcgcgt gcgccgtttc tgcggccggc
   833281 agcccggttc gcgcgtcagg ccgcatctct tccgcaagct ctatccctat ttgcccggcc
   833341 tccagcagca atcggcagag tacgttgctg cgtttttcgg tgcgggggac gttgctctcg
   833401 acgacccgct cttttcgcat cggccgcgct tcaagggcac ggcggcaacc aagatgttct
   833461 tctccgcaga tctgcgcgcc gagctcaagg gctacgatgc ggccgaagaa ctcgtcggcc
   833521 ggcttcccac ggctttcggc cgctggcatc cgttgcacca ggcccaatat ctcgaaagcc
   833581 gtttcctgct gcccggatac attctctcga gtcagggcga tcgcatggcg atggcgcatg
   833641 gcatcgaggg ccgtttcccg ttcctcgacc atcgacttgt cgagttcgcc gcgaaactgc
   833701 cgcccgagat gaagctcaag gggctggtcg agaagcatat tctgcgcgag gcgaccaaag
   833761 acctgctgcc gccggcgatc ggcaaacgga cgaagcagcc ctatcgcgcc ccggacagtc
   833821 actccttcag cggagcgggc gaactcgact atgtgcgttc ggctatgggt gaggaagcga
   833881 tcgccgccgg cgggctcttc aacgccaagg cggtcacgaa gctctacgag aaatgccagt
   833941 cgcggccggc ctcggggttc cgcgacaatg cggccttcgt cggcgtcctc tcgacgcaac
   834001 tctggctgca gacattcacc ggcaacagcc tccgcaaggc tgaagctgcg taaaaacact
   834061 gaaaaaaagg ggttagtgga atgactcaaa cgatcaagga caaggtcagg acattcgtca
   834121 tcgagaactt tctcttcggc gataccgcat atgaactcgc cgacgacgca tcgctcatcg
   834181 agaacgacat catcgattcg accggcgttc tcgagctggt ggccttcatc gaagacgatt
   834241 tcggtatcgc gatggccgac gccgatatcg tcccgcaaaa tcttgactcg ctcgcgcgga
   834301 tttcggcttt catcgaagcc aagggcgccg tgccggtttc ggcttaaacg gaaagctgca
   834361 ggggcctcac cattatgcgg ttcgagcaat tcctcatcag gaacgccgcg gcgaacgggg
   834421 caaaaacggc gctggtcacc gatcgccggc ggctcagcta tgccgaactg gacgatcttt
   834481 caacgcgtct cgcggctgct cttgccgcaa acggcgtgaa gcggaacgat cgcgttctgg
   834541 cgttcatgga taattgctgg gaggcggcgg tcgcaatctt cgcgatcctc aaggccggag
   834601 ccaccttcag tccgatcaac gcttcgacca aagcagacaa gcttgcctac gtaatcgcgg
   834661 attgcgaggc ggcggcaatc ctgacgcagg cgaaactgat gccggtcgtt accgaggcgc
   834721 ttgcgcttgc tcccggttat cggcctttca ttgcctcggc cgcggcgcca ggcgggcgca
   834781 tgcccgacgg tgccgcttcc ttcgaggaat gcctgacagc cgtacccgcc gctgtttcgc
   834841 acgggggtat cgacatcgat ctcggcatgc tgatttatac ctcggggtcg acgggacgtc
   834901 ccaagggcgt gatgatgacg catcgcaaca tcgacgctgc ctcagaatcg atcactacct
   834961 atctccgcaa cacgcctgaa gacatcattc tgaacgtact gccgctcgct ttcgactatg
   835021 gtctttacca gttgctgatg gcggtccggc tcggcgcgac gctcgtgctc gaaaaatcat
   835081 tcgccttccc gcaggcgatt ttcgaccgga ttcgggccga gggtgtcacc ggcttcccac
   835141 tcgtgccgac catggcggcg atgatccttc agatgcgcga tctcgagccc ggcttcctgc
   835201 caagccttcg ctatctctcc aacaccgcgg cagctctccc gccggcccat attgcgcgcc
   835261 tgagggagct ttttcccggc gcccggctct attccatgta cggcctgacg gagtgcaagc
   835321 gctgcaccta tctgccgccg gaggagctgg atcgccggcc gggttccgtg gggatcgcga
   835381 taccgaacac ggaagccttc gtggtcgatg acgagggaaa ccggctaccg cccggtgtgc
   835441 ctggtgaact ggttatccgc ggcccgcatg tgatgcaggg ctattggcgc aacgctgccg
   835501 cgaccgagcg catgctgcgc tccggtcctg atccgtggga aagggtgctt tataccggcg
   835561 atctcttccg caccgacgag gagggcttcc tctacttcgt cggccgcaag gacgacatca
   835621 tcaagacccg cggcgaaaag gtggctccca aggaggtcga gaccgtgctg cacgctcatc
   835681 cgggcgtagc cgaagccgtg gtcatcggcg tgccggatcc ggtgctcggt gctgcgatcg
   835741 gcgcgctcgt cgtgctgtcg gacccgtctg tgaccgagag ggagattatc cgccactgcg
   835801 cccgccatct cgaggatttc atggtgccga aaatcgtcga gttccgggct gaactgccga
   835861 agaccgatac cggaaaagtc agccgccgcc tcgcggccga aacattggag ccagcagaat
   835921 gaatatccgt ccggatcaga acaggcttgc cttctcggcc gaccctttga agatcgacga
   835981 agctgccgag acggaccgca ttgtcgccgg tctgcgtgcc caactgcgca gcctgcgcaa
   836041 gcgcggcctc gtgctcggcc tttcaggcgg tatcgattcg agcgtttccg tcgcactcgc
   836101 cgtgcgggcc gtcggagcga agaacgtctt ctgtctcttc atgccggaaa acgattccga
   836161 tccggaaagc ctgcgcctcg gacgtctcat tgccgagacc ttcggtgtcg aggcggtggt
   836221 cgaggatatc ggaccgacgc tcgacgccat gggctgctat cagcggcgtg acgcctttat
   836281 tcgcgaactc gttcccgaat acgggcaggg ttgggcatcg aagatcgtca tcgccaacgc
   836341 gctcgaaggc gatggctaca atatttcctc gctcgtcgtg caggatcccg acgggcagca
   836401 gacgaagttg cgcatgcccc cttccgtcta tcttggcatc gtcgccgcga ccaacatgaa
   836461 gcagcgcacc cgcaagcaga tcgaatattt ccacgccgac cggcttaact ttgccgtgct
   836521 cggcacgccg aacaggctcg aatacgatca gggctttttc gtcaagaatg gcgacggcgc
   836581 ggccgacgtc aaaccgatcg ctcatctcta caagtcacag gtttacgcgc tcgccgccca
   836641 tctaggcatt cccgaggaaa tccggcgccg cccgccgacc acagacacct actcgcttga
   836701 gcagacgcag gaggagttct atttctccct gccctatgat cgtatggacc tctgcctctt
   836761 tggcctcaac agcggcttcg gcgccgacga ggtcggacgc gccgccggtc tcagttcggc
   836821 acaggtcgaa cgcgtctggg cggacataac cgccaagcgc aaggcgacgc gatacctcca
   836881 tctaggccct cagctcgttg aaccggtcca ggaaatcgaa cactgagcgc tccaaacagc
   836941 agacgccggt cgcgttctga atatgaaccc gatcgcacgc cccgtctctg aacggggcgt
   837001 gcgatcggcc ggcttttact gagagggtgc aggcgtggtc ggtgccgggg ccggttccgt
   837061 gggggcgggc tcggtcgcgg gcggggtttc cgtcgccggg ggcgtttcag ccgtccctgg
   837121 catgaagaat atgaccgcga gaatgatgat cgcgaggacg atgatgccaa tgatcacgtt
   837181 tcggttcatg ctatttcctc cgctgctgac gatcatctcc ggccgttggg gcggtagcaa
   837241 atggggaagc agccgctcaa cgttcaaccg gagatgagcc gatagcgtaa catgagtctc
   837301 gccaagcaag tacatagctc ttgaaaggga tgaactatcg agtattcgat gccgcgcggg
   837361 cggtcacggc ggggtgcgct tctctatagc gccaccgcta acgagatcac tccccccgat
   837421 ccaaaaactg ttgctttcct gcaacggacc tcggtctgca tttgcaattc gaaattgcgt
   837481 acttgcccat cggcgggtct cgtgccagga tagacaaatc cgcaattcaa atcagaggag
   837541 gcgtaagtga atcctattct cgtgtttgtg cgcctctccg gcggaaccgc tctcgtagcc
   837601 tccatgcgct ccgcatcgag cttgaatcgc gattaatccg ggctttaaag ccggattctg
   837661 ccctttggcg cttccaacct aacctgacgt gatcggccac cggagcgatt gttcgcattc
   837721 ctgactccgc cccggcacgt ctttggctct tcgaaaggac ccggctgcat cgatgcgccg
   837781 ggatggaaag tcatgcgtga aacacaatct atagctgtcg acctccttgc ggggacagtc
   837841 gatgaactct accggaaatt cggtgcgtgg aagaccgcac gcgccttgat gaccgccgtt
   837901 tggaggcgcc gtcaagcgca aaaccagatc tcgcacctgt cgaatcggat gcgtcgggat
   837961 atcggccttc cggacgcaga agaggaattt tcggttctgg acataggcgc tctcggcaag
   838021 gtcaaggcgg ttcgtccgga ttgacatgct tggggctgat ccgctccgca acggcctcta
   838081 tcgagcgagg ccgtgaaaag ggagggggca aacggttcct ctcccgtttc gcaatggctc
   838141 ttcggggccc ggaacggacg cgctgccttc gcgagcattg atgctccgcg ccgtcagccc
   838201 tgtgcaagct ccaccattca gcattgctgc ctagaactgg tcgccggcac gggccaatcc
   838261 tgtgtggaac gggtcgaaga ccaggcaaag taggaggccc ggttaaccat ttgttaacca
   838321 tggctcgcct acatcttggc aaccaaaaat taacgaagat gaccaaagtg ctaacagacg
   838381 ctcgctcgat ccgcatcaag ggccgctcct tcctggcgct ggtgctctcc ccggaactgc
   838441 cgctcgactg gtggctcggc cggcttgacg acctcgcttc ccgttcggcg ggtttcttcc
   838501 tgggccgccc ggtggtgctg gacgtggcgg acctcgaaat cgaccggaag cagttgaaaa
   838561 gcctgctgga agaactcggc caacgcaatg tcagggtcat gggaatcgaa ggcgggcgtc
   838621 cctcgctttt cgaaccggga atgccgcccg ctatgaaagg cggccggccg gcgccggatt
   838681 tcgaagtgcc tgaggcaaat ccggcggaat caccgaaggc cggcaagggg aaagccgccg
   838741 cgccggtcat cacggaagag gttcagccgg ttcgggcgac ggcttcgatc attgttcgcg
   838801 agccggtgcg gtcgggacaa tcggtcatct tcccggaagg cgacgtgacg gtggtcggct
   838861 cggtggcgtc aggcgcggaa atcgtcgcag gaggttcggt ccacatctac gggacgctca
   838921 gggggcgggc gctggccggc tcggtgggaa atgcctctgc gcgcatcttc tgccgcaggc
   838981 tcgaagcgga gctgctggcg atcgacggcg tctacaagac cgccgaagac atggcgccga
   839041 acctgcgagg gcagtcggtg caactctggc tggaaggcga ttcgatcatg gcagagagac
   839101 ttaactgagc cttatgcggg ctcgatttta aaagattaga gcggggatgc gggcggaaaa
   839161 ccgctcacag ttttccatcc gctctgacaa caggagcggg aagatggcga aagtagttgt
   839221 ggttacatct ggcaagggcg gcgtcggcaa gacaacgtcg actgccgcac tcggcgcggc
   839281 gctggcgcag cgcaacgaaa agaccgtcgt cgtcgatttt gacgtcggac tgcgcaatct
   839341 cgacctggtg atgggcgctg agcgcagggt cgtctatgac ctggtcaacg tgatccaggg
   839401 tgatgcaaag ctgccgcagg cgttgatccg cgacaagcgg ctcgacaccc tcttcctcct
   839461 gcctgcatcg cagacccgcg acaaggacag cctgactccg gaaggcgtcg agcgggtcat
   839521 ggccgagctc aggaagcatt tcgactggat catctgcgac agcccggcag gcattgaacg
   839581 cggcgcgacg ctcgcgatgc gtcatgccga cctcgccgtc atcgtgacca atccagaagt
   839641 ttcctccgtc cgcgactccg atcgtattat cggcctgctc gacgcaaaga ccgaaagggc
   839701 tgagcgcgga gagcgggttg agaagcacct gctgctgacg cgctacgatg ccgtccgcgc
   839761 cgagcgcggc gacatgctca aggtcgatga tgtcctcgaa atcctgtcga tcccgctcat
   839821 cggcatcgtt cccgagagca tggacgttct caaggcttcc aacctcggtg ccccggtgac
   839881 gcttgccgac agccgcagcg ctccggcgct cgcctacctc gacgcggcgc gccgtcttgc
   839941 aggggaaaca gtgcctatga ctattcctgg cgaaaagcgt ggctttctgg gtaagatatt
   840001 cggacggagg gcagcatgag cattttccgt tttttcagca agcagacttc cgcgccgacg
   840061 gcgcgcgaac gcctgcaggt cctgctcgcg cacgagcggg cttcggtcgg ccagtcggac
   840121 ctcgtggcgg tactccggga ggagattctc gccgtcattg ccaagcacgt ccaggtcgac
   840181 cgcgacaagg tgaatgttac gatggagcgc ggcgagcacg tcaccacgct tgaagtcgac
   840241 atcgaaatcc cgataaaggc cggcgtgcgc gcggcctgaa ccggccgcaa ctttggatcg
   840301 caccaccgcc gtgcacatgg acgcttcaaa gacggacgaa acagattccc gttcgaagcg
   840361 tgttgttcga agttggatcg cttcgccgcg aaatcggcga agcgacccac cccctgcatg
   840421 tcgcgccttg aaacgccgca cggaccgttt tatcggactt tggtccgaat caagcccgac
   840481 aatcgtccga ccgctgaaag cgaaacgtct gaccccctcc gattgcagtt gacgtctgga
   840541 ccggaccgtg aacaaagatg gggcaatagt cggtgaaagc aaatgcacag gctttcctga
   840601 tcaattgacg tcgtgtcggc cgctgtagcc gacggtccgg tctgatgtga aaatgttgcg
   840661 cgaggtcgcg aacaggtgca tgccggtaaa attcttcagg aggagcgcga tggtcacgcg
   840721 tcggaacttt cttgcagcac tatgcggggt ttcggtcggc cttcccgttg cgctatcgcc
   840781 ttacaaaatc gtcttatcgg gttcggacat cgaactggag ttgcaagccg ctctcgcaaa
   840841 gggaggcggt agtggcggcg ggcgcggagg cggcggcgga aacggcggcg ggcgaggagg
   840901 cggcaacggc gggggaaatg gtggcggaaa tggtggtggc cgcggaaacg gaaacggcag
   840961 gggcggcggc tcgggcggaa attcgaattc cggccgtgcg agcggaaaag cggctacgtc
   841021 ggtagaaggc ggcggctcga tcctgcgcgt tcgtcaccgc gacggcatca gcgaagtgat
   841081 cgagggcgcc cgttacatca tgaaggattc acgcgggcgc acgatcgtca accggcgagc
   841141 aacgtcggcc gacaggagac ggcttctgtc ctttattgac tgaccgggcc ttcattgact
   841201 gaccggacgc cagtcgactg catcgcgcag caccatggcc gcctctgtcc ggttggcgac
   841261 gttgagcttc gccatgatct gcgtcatgtg atgcttcacc gttttctcgt gcagatcgag
   841321 cttgcgggcg atctgcttgt tgctcatgcc ggacgcgacg agatgcagga cctcctgttc
   841381 gcggcgcgtc agctccgcga cgaggttgga cttggccggt gcaggattga gcaactgccc
   841441 ggtcagcagc ttggcggaaa gcgtgggcgc gacatagctc tctcccgaag cgacggtgcg
   841501 gatgacgtcg gctagcgccc tggcgccgat ccccttgagg atatacccct tcgctccttc
   841561 cttgagagct gccgcgacgt cgtcattcgc ctcggaaacg gtaagcatca caattttctg
   841621 cgaaggcgcg acggtcagaa ttgccggaat ggcgttcagg ccgccgccgg gcatggagat
   841681 gtcgattagc atgacgtcgg gattgtggct gcgcgcgatg gcgatcgctt cgtcccgcga
   841741 gccgccttcc gcgacgatct caaacccgtc gatttctgac aggctacggc tcacgccctc
   841801 cctgaacaag gggtgatcat cgatcacggc tactcggatt cccatcatca tgcctgctcc
   841861 atctcctcaa ggccgagtgc catccggaca atggtgccgg gggcgttggc gttgatctcg
   841921 aatgttccgc cgaggctctc gacccggccc ttgaggccgg cgagcccgag gctcgtcggc
   841981 tgtacctcgc cggggtcgaa gcccggcccg ccatctgcaa cctcgacggt aatcttgtca
   842041 ccgttcgtgc tctgcgtcac gcgttgagcc acgccaccgc cgtgacgata ggcattgtta
   842101 agcgcttcct gaacgaaacg gtatatgcag atttttgccg atgcggaaag acgtattggc
   842161 gggccgatca tcgataagtc cacggtcgtc ccggttcgtt gttcatgagc gcgtacgcag
   842221 cgctcgagga tttctctcag gccggcggtt tctatctgcg gcagcacgag gccgctgcaa
   842281 agcgtcctga tctcgttcat ggcctcgtcg aggctgccct taatggcggc gatttcgcgc
   842341 tcgcggacgt cctccggcgt cgacgggctg acaagcttgt tgctgtccag tcgtagcgaa
   842401 gcataggcga cgagttgtgc tgggccgtca tgcaggtcgg cgccgatccg ccgcaacagc
   842461 gtctcgttca gcgcggttgc tcgctgggat gcctgacgga ggcgcccccg cagcgcctcg
   842521 ttctgcgcaa gcagtgcgga aagctcttcg acgcgctgcc cgagcgcctg gcgttgtttc
   842581 tcgatcgttc tgctcccgcg caacacgatc gccgacaagg cgatgaaaaa ggcaagcgtg
   842641 aagccggcaa ccgcaagcca tgtatgaagc cgcgcccgat tgaggctctg ttggaattcg
   842701 tcggcgattt cgtgaaattc cgagacggcg acgacttctc cggaccaggg ttggaggagg
   842761 ggattgtata tttccagcag agggctgttc gaaaggcgtt ccgtctcgcc atcggcctcg
   842821 tccagaggca tgaagcgggc gaccatgtcg ccatcgaacg ccgtcgtcag ttccggaccg
   842881 agctcaaact tctgcccgac catagccttt tcgcttgaat agagaacggt tccgtcagcg
   842941 cgccagaggc gaaacgaggc gagccgatcg cccagggcgc cttggccgag tgtttcgtcg
   843001 agcgcccgcg cgactgaatc gtccagcacc tgcgtcgttt gcatgtccgg cagaagcggc
   843061 gctatcacgc tgtcgacata aagagccgtg gttgccgcgg aattgcgcgt gaccgcttcc
   843121 tcaatcaggc tcgtcacgaa ggcgctgacg acaagcatcg ccgcggcggc aaccgagccg
   843181 ccgataatga ggaactgcct ggccagcggc tgagagttcc accgtctgat gaggtcgtcg
   843241 gcgcgcacga gaaatctcac gatggcccgc tcatttcgtc gccggcactg ctgcgttgct
   843301 ttgcactgtc aacttagcat ttccggcctg tcggtcaacg cgcgccagcc ttaccaccct
   843361 tggtcatagc gcaaattgga cttttgacgt ctgcacccac ggacctaagt cctatcaacc
   843421 gacgcattgg tcccgggacc gtggaacccg ccccagttgc acgttatcgc ttcatcaatt
   843481 ggttgagaac gtcggctgcc agctgcggcc gcggcatcag ataggaggcc cccatgcctg
   843541 tttccaaaat cgtcggaaga ggactcattg cgctggcgct tgcaggagcg cctctagcgg
   843601 gcgttgcgcc tggaatgtcg gacatcgcct ttgccaaagg tggcaatggt aatggtggcg
   843661 gcaatggagg tggcggaggc aacggcggtg gcggtggcaa tggtggcggc catggcaaga
   843721 gcggaagcca ggggagccac ggcaaaagcg gaagccacac aaaggcccgc gcggattccg
   843781 gcaaatcagg cggcgaacgc gctggcacgc cgcgtttcct ccaggggctc ttcaagcagg
   843841 gcaagaaggc cgaacgtccg acgaccggca aggcggttaa ggcggccaag gctaacgcta
   843901 tcgcaaaggc tgttcccacg ccgaagccca aaaaccctca ggccgaaatg gcaaagctga
   843961 gctctctcgg caggaactat cacgcttacc tgaattcgaa cgatccgcgg atggcggcga
   844021 tctccgccta tgctatcgcc tatgcggagt tcgaggccga attcggctcc gatgtcattc
   844081 cgaccgatcc ggcgctcagc gacgaagcgc tgcgcgaggc catcgcaagc ttcacgaatg
   844141 gcggcgaggt tacggacgcc actctcgagg acgtgaagga gacgctcggc gttggctcat
   844201 ctgtcggaaa gatagatcag atccgcgaac atctcctcga cacgacagat gatgaagtca
   844261 tcatgaccga ataacgcgga acggggcacg tcacggcatg gaccacctga gaagattcaa
   844321 ccacgtcgtc ggtgccgtga cccaggcgat gcgggagggc cggctgggct tttccctaca
   844381 gcaggtcaat ccgatcgacg aggcgggggc agtgttttat tcgcaatgcc tcggccgcct
   844441 cgtggagcgc gacggtgagg tcaggacaag cgacgagttc actgcgtttc tcgaagcgtc
   844501 ggggcgtgtc gcgtcatacg atcgctacat ggtcggcctc gcgttggaat ggctcgagtg
   844561 taatccgtcg cacgtccttg gctgcaaaat ttctaccgga aacatcttcg acgagcacgc
   844621 ctggtccgag tttcacgatc tgctttcgcg caatcgcgag atggctccgc gcctcgtcct
   844681 cgagatatcg gagagcctgc cattggcgac cttgcccact gcagtggcgt tcttggaggg
   844741 cgtgcgcgcg ctgggctgca aaattgccct ggacagtttc ggaacgggac actcgacgcc
   844801 agagtcgctg ctgtcctttt cagtcgatat cgtgaaactg gacgcattct tcatcggccg
   844861 cggcgggaaa gacttcctcc atcatctggt cgggctcgct tcctgcgttg cgccgatggt
   844921 ggtcgtggag ggtgtcgaga cctacgcgca attcgaagtc gcaaaaaggg cgggagcaac
   844981 gcatgtgcag ggcttccttc tgtcggagcc gaccttgtat cccgtctatt gcggccagcc
   845041 ggcgccgccg ctggccgccc tccacagcac cgcgggatac cgtcagttgc attcctgacg
   845101 aagcgatctg cgaccatttc acctttgcat ctcccacgat cctccgctcg atgccgcagg
   845161 tatcgaacat gtgatcgacg gtgagtttgg gaatccgcga gactcagcta aaccgtcggc
   845221 aggcgatttt cgctttctca ttccacctac ctgcctgaga tgtttagcaa aatgcaatta
   845281 caaaggcgca cgttccttct cggagcgatg tccgcaaccg cagcccttgc gggatgtacc
   845341 acgtcgatgc ccgcgactga gcgcgctccc gtgccgcgtc tggtgagccg cccgctgggg
   845401 ttgccgggcg atgccgaact ggaagcccgg tatgcagccg tggaagatgg cgggcacctg
   845461 atcccggccg ttccctacag acaaatggat ccgaaatatc ttcgccagcg tgtaccggat
   845521 ccgaccggcg aaccggcggg aaccgtcgtg gtcgatacgc ccgggcgcta tctttatctt
   845581 gtcgagcccg gcgggacggc gatgcgctac ggagtgggaa ttggccggga gggatttgcc
   845641 tgggagggcg atggaatcat ccattggcgc caagcctggc cgcgctggaa gccgccggcc
   845701 gagatgatcg cccgcaggcc ggagcttgcg gaatattcgg tcgagaacgg cggcatggcg
   845761 ccgggcatca agaacccctt gggagcgcgc gcgctttaca tctttcagaa cgggcgggac
   845821 acgctctatc gcctgcacgg tacgcctgag tggaactcga tcggcaaggc gacatcgtcg
   845881 ggatgcgtcc gcctcgtcaa tcaggacgtc atcgatcttt acaagcgcgt gccctatcac
   845941 gcgcggatag ttgtctatca gacgccgctg attgcgcagg gccaggcctg agttcactcg
   846001 aaccggctgc cgatcaaccg gctccagtgt tccccggcca gcccgttgat gaagccctgt
   846061 gcgtggcgga aggcgtcgac gagttcttcc tcgcgggagt ggacgacggt cgaggcggca
   846121 tggacgaagc caatgcggcg acccatcatg gcctccagca gggccggctg ggttcggccg
   846181 cgaactgccg cagcaccgcg gccggccgcg tgctctatca ggcaatcgag caccggcccc
   846241 gcctgtcccg acagagcgag gacctggagc acgcgggctg ttccgccggg ctggagatgg
   846301 tagaaaaacg cgccgacggg cgcaccgctc cgggtcttca gggccgcgaa taccggctcg
   846361 ccgaataacg gcttcttctc agcatcttcg aggatatgct cgagctggct ctcggcccag
   846421 gccggctgta tggcaaactg tctggtgagc ggtgcaaaga gctcggcaaa gccatgtcgg
   846481 tcaatctcgg cgacctggag cgatccctgg gtggttgcgg ccgcgggcac gccagaccag
   846541 cgcaattcgc cgcgccccat cttgccgcga tagcgacggt cgaatgcatg cgccaagggc
   846601 acgagcgcgc ggaccgggcg cagcctgctc gcgacgaggt cgagggcgaa ggatgccggg
   846661 cggatgacgc gcacccagtc cagactgtat tgtggaagca cgataccccg cagcttcgtc
   846721 cacatctgcg tcgaaacctc gctggcggtt tcgctgaagg agaggtcctg cggtccggca
   846781 aggaaagctt tcagcagccg cgcgccggcc atcgggtcgc cttcgcggcc ttcgaccatc
   846841 agtgagccgc agatagcggc gcgcagccgc cggccacgat aggtcatcgg aagagtgttc
   846901 gccccgacga atcccgatac gcggccgtcg tcattgacgt gcacgagcgg gcggatgtcc
   846961 gggtcggtgc cgggcgcatc gacatagagc cgccgcaggt aggcgacgaa cgcagccggg
   847021 ggctcctctt ccctgttgcg aaagaccttc tggaagagcc gcgcgacagc cgggatgtcc
   847081 tcggctgcaa gcgaacggat ctggctcatc tgatttccca gtccgctgcg gcagtcgggc
   847141 cggccagcct gcgtacccgt gccacgcgcg gcttgccggc cgcatccgtc gcgaaagaaa
   847201 ccgcgtcata ggctttcgtc cgcgcaagca gggcggcggt ctgacgatcc tgtccctctc
   847261 cgaattcgaa gaggagccaa ccgccgggct tgagaaaggc gacggcttcg cggatcagcc
   847321 gctgatggat ggatatgccg taggggccgc cgtcgaaggc ctcccgcggc tcgctcgcga
   847381 gaagatgcgc gctgtcgctc tcgaggcggg atgtcgagat atagggcgga ttgcagacga
   847441 tcatgtccac ggcttcctcg aggccctctc ctgccagggc ggcgaagagg tcgccctgcc
   847501 ggacgaagac ccgatcgccg agcgcgaggc gctcgacatt gcgccgtgca agcgcgaccg
   847561 tgctgtccgt cagatcggcg ccccagacgc gtgcgagcgg cacctccgcg gcaatgccca
   847621 aagcgagatt cccggaaccg cagcacatgt cgaccacggt cgccggccgg gccgcctcgc
   847681 gcaggattgc tgcggcggtc ctccccagca gttccgtctc ctcccgtggc acgagcacgc
   847741 ccggtgcgag ttcgaggtcg atgtccatga aatgcacgag ccgcggtgcg cgaccctcgg
   847801 tccggccgtc aagatgattg tcgccctgca gcacgaaggc tccttcggtt gtcggagtgg
   847861 gtgatcgttc cggggcacag tagcgcgtcg aggtaaacgg aagctgaaat gaaggcggct
   847921 cccggcggcg gatcgagggg agcagcactc ccggctgacg ttaaccggcc aatcatttct
   847981 gtgtgctaga gcggtgcaat cggcgagggc gccttccaac aagttgagac gcgggacggg
   848041 ggcggaagac cgcgcggact tttcctcatc ccgctccagg acagtcaggc agatcggatg
   848101 gccacggacg gtgtaacgga acagcgcgga tacaaaccat tcctgccgat gctcatgtcc
   848161 tatgtcgcct ccggcggcag tctggtacta ggctctgcgg cgcagctcct caccttcgct
   848221 atcctcgcac gttggctcgg tgtccacgag ttcagcgtct tcgtcgccat cactgccgtc
   848281 gccaacattg ccgtccatct ctgcgggctg ggagcaatgg agtgcctcgt gcggcgcgtc
   848341 gcacgcgacc gtgcgatcta tccgcaaatg ctcggacaca atatcatcct gacgtcgggg
   848401 agcggggcgg ctctggtgct tctgggagcg gtggtcctgc cgttcttctt tacgctttcg
   848461 ccagatcgta tgacgaacgt cgccgtgatc acgctcatgc tggtcaccaa tatccttctg
   848521 gtccgggtta ttgtccttac ggagcagata tttatcgctc atacggactt tgcctctgca
   848581 aacaaggtcg tcgtcggttt tgcggcggcc cgaacggtcg cggcggcact cgcctgcatc
   848641 gccttcggtg cgaccaccgt cgcatcctgg gcggtctggc agtttctctg ccacgtcctc
   848701 gtggcggtct gttgcatgtg gtccgtccgg ctgctcggcg cgcccagcta ccgtctcgtg
   848761 cgggaggaac tcccgcaggg cctctatttc agcattccgt ttatcctgcg tgcgttgcgc
   848821 cagaatgccg atctgctcgt gctgagtctc gtcaccacgg ctgagatcgt tgcgagctac
   848881 agtgtcgccc ggcgcatatt ggagagcagc tatctttccg tggaggcgtt gaaccggctc
   848941 atttatccgg gctctgcgcg ggccacggcg gcgggacttc accacgcact gcagcgagtg
   849001 cgcagggtgc tcgctgcagc caccgtgatc agtctcgctg cggccgtcac ggtattcgtt
   849061 ctggcgccga tcctgcctta tctcttcggc aaggagtatc tttcgctggt gggctttgcc
   849121 agaacactct gctgggtcgt ggtgccgctc gccatgtggt cggtcgcggt cgaggcactc
   849181 ggcgcctccg gcgatcacgc cgctcgcgcc gccgttatgg gcttcggcag catcgcaggt
   849241 accggcctcg ccgcatgggc gagttggtac gcgccgcccg ccgggacttt catatccttt
   849301 tatgtcatcg aaatcgcgat ggtcgtcgcg tcatggagcg tgttcctgca ttttgtgcgg
   849361 cgcgaccgcc aggcggcaat caccttcggg agcggcagcg catgacgatc gaggtggagg
   849421 aaatccgcgc gtcggagaat attccggccg gtgcagggcc gcgccgcaac atccgcccca
   849481 tgacacccgg cgatgtccct gcagttggac ggctgttcaa cagaattttt cgagggcatg
   849541 atcgcgcgcc cggggacgat cttggccggt atatagagac ggtcttcttc ggcagccccc
   849601 aatatcatcc cgacctcggc agcgtcgtgc acgagaatgc tgccggcggc atagacagcg
   849661 ccattctatc ggtgccgatg gcctttatgg tcaatggtca cccgatcacg gcgcgtcttc
   849721 tctgcgcctt catggcggag agcaaggcgg gagccgtcgg agcggctcgt cttgcgcgca
   849781 gcatgcgggc ggctcgccag gacatgtgct tctccgacaa cgcgtcaccg gtaagtgccg
   849841 accattgggc ggcgggaggc ggtctcgttc tgccgatcca gagcctggaa tggcagcgtt
   849901 cgtttttgcc cctgacggcc gcggcgatac ttgccagccg ccatctccct gtcgtgggct
   849961 cgcctattct cctcggcatc cttggcctgg tcgaccgcgc tctgcggcgg ctgcggccct
   850021 cgatgcggcc gaaggccgag ggcgcttgca ggatagagcc cgccggcgtc gaggagttcc
   850081 tggaatgtgc gatgcccatg ctggaacgct tcgcgatccg gccggcctgg tcgaaatccg
   850141 aattcgattg gctcgtgcac attgcatcga tgaaccgaag cctcggggcg ctagagtgcc
   850201 gaaaggtcgt tctggcggac ggccgcacga tcggtgcatt tctttttttc cgcaagccga
   850261 cgggcatcgc cacggtgctc aatctggtca cggaggaggg gcgtgaacgc gatgtcgccg
   850321 cggcgatgtt cgcgcggctt gacgcggaag gctatgcatt ggctgtcggc atggctcagc
   850381 ctttcctgat gaacgcgata tcgcgccagc gatggttgtc tttccggcac cggggttatt
   850441 tctgtttggt gacccgtcat gcggaactcc ggcaggcggc agaacgcaac gacatctata
   850501 tcggcggcct cgcatcggag acctggagcc ggctgctgac cgatttttaa ggccggtggt
   850561 cccaggattg atgatggtaa ctccggtgtc gccgaaatca gcgacatcgc aacttaatcg
   850621 ttgattgcag catccgaacg ccgttgccgg cgaagcctgt ccgttttttc aagggcctta
   850681 aaacagcgtg gcaggaagcc ctgccccaga ggttaccacc cgaaaacgcc gcttaaccga
   850741 atattcaccc tgcaagcact aaatctgcgt ggggcattct gcttatgaag caataagcag
   850801 atgggtggcg acaagggtgt ggggaaaagc ggatgtatcg gcgcagcgag cccgagggac
   850861 agggattacg ccatggaagg ccttcacagc gccttcgccc ggctgggggt tcgttgcttg
   850921 acttcgtgcc ggcctcggcg gaagagactg ctcctcccga agaggcgcgc actctagaga
   850981 aggttggcgc ctccgtccgt gtcgtggacc tgccggctcc gagccataac gcacgcgctc
   851041 ctgaggagcc ggcgtccgcc gccgatttct tcccgcaact ccacctttta ggcagcatcg
   851101 ggatcaacga catcatcgtc tggcttcgcg acgggatccg ctggatcgtc atcgcgctcc
   851161 tcctctccgg tgccgcggct ttcgcttatg ccgtgacggc gacgccgcga tacaccgttt
   851221 acaccgacct cgtcgtggac ccttccaatc tcaacgtcgt aagcgacgac gttttcacga
   851281 ccaatccgca gcgagacgcg caattgctgg aggtcgaaag caaactccgg atcctgacat
   851341 cgcgcaatgt gctccagcgc gtgatcgacg agctgcggct ttccgaagac ccggaattcg
   851401 tcaagccgac cttgctggac tggctgaagg cgctgcttgc cccgcgggac ggtaagacag
   851461 acaaggatct ggcggccatg cgcgtcctgt cggagagggt cgaagcgcgc cgggaggagc
   851521 gctctttcgt cgtggtcctg aaggtctgga gcgaggagcc tgccaaagcc atcgcccttt
   851581 cggacgcgat cgtcgaggcg ttcgaggcgg aactgttcca gtcgtccgcc gagagtgccg
   851641 gccgggtggc gcagaacctg aacgcacgcc tcgatgaact gcgccgcaac gtcaccgagg
   851701 cggaaaggag ggttgaggac ttccgccgcc agaacggtct gcaatccacc aatggcgagc
   851761 tcgtcagcaa tcagctttcg agcgagctca acacgcaggt tctggacggt cagcagcgct
   851821 tcattcaggc ggaaacgcgc tacaggcaga tgagctccgc cgttgccggg ggccggaccg
   851881 ccagcgcttc ggtgttcgag tcggccaaca tgaccgatct gcgccagcag tataatgcct
   851941 tgcagcagca gataggatca atgcagctta cctatggaga gcggcatccg cggctcgtcg
   852001 ccgcccgctc cgagcgtgcg acgctggaaa ccgcgatgaa ggatgaagcc cgccgcattc
   852061 tggagcgcgc aaaggccgat ttcgatcggg agcgaaaggc gctcgctacg ctgcgcggca
   852121 aggcggacaa cgaaaaatcg aacgtcttca ccgataatca agcccaggtg cagcttcgcg
   852181 acctcgagcg cgacgcgcgc agcaaggcgg cgatctacga aacgcacctg gcacgcgcac
   852241 agcagatcac cgagcgccag cagatcgaca caaccaatgt ccgcgtcatc tcgcgcgccc
   852301 tgccgccgaa tgcgcgaagc tggccgcctc gtaccctggt tctcctgatc ggcggcgcct
   852361 ttctgggtct cgccctcgga attgctacgg ccctcgccct cggcctttgg cggttccttc
   852421 gcggcaaaac gcgcgcggct gcctgagggg ccctgtcagg atggatcgcg ggagctacgc
   852481 agaggccgag cggacgagtg gatcgacggc acgtgtcggg accgccctct tcatcgcgat
   852541 tttcctgttc ttctggattt ccatcaaccc cttcgtggac ttgaccggcg aggcggtgct
   852601 ggatccttcc gccggaaatt ccaaccggct gaaccagatc atctcgctcc tgcttttcgc
   852661 cggcatgctc tgttacggac tgatccatcc cttgcgggaa actattctgc ggccccggtt
   852721 gctgctggcg atcctctatt gttggttcat cgtcgtttcg ctgatctcgg ctcatccgat
   852781 gctcggcatc aagggcgtga tcctttccgt aatggtcacc gtcaatgcca gcatctacct
   852841 cttgctgccc acttcggaac gccacttcgc caggatgctc ggtatcgcca tcctcgtcat
   852901 gctgagcgtc gcctattacg gcatcgtctt caacccgtcg ctcgccatcc accaagccac
   852961 ggaactgcgc gaaccgatga atgcaggttt gtggcgaggt cacttccctc acaagaacag
   853021 cgccgcggct gcgatggtga tcgcagcctt catcggcctc ttcgtcatga acgcctggtc
   853081 gcgcgtcgcc ggcatcgcca tcgtcgcgct ttccttcgtc ttcctcgtca ataccggggg
   853141 gaaaacgtct acggcaatgc tgccggcgat tctgctggtc gccttccttt tcgaaaaggt
   853201 gcgcttcctt cgcatcccga ttgccgttgg cggcgtcggc ctgttcaatc tgttcgccgt
   853261 cggctcggcc gtcattgttc ccttgggtga attcatcaac ggtctcggcg ttgacgcaac
   853321 ctttaccaat cgcgccgata tctggcgttt cgccttcggc gcgctcgccg aacagcccct
   853381 cacaggatat ggcttcaagg ctttctggca gacggaagaa ctcgtctata gcggcggcac
   853441 ggttgagacc tgggccgtcg cggccgccaa cggacataac tcctacctcg atatcgccct
   853501 gatgacggga tttcccggac tcgccctgac cctgatctgg atactcttcc taccgctccg
   853561 caacattgcg cgaatcgctc cggagcgcga acacacgcat ctgacgaggc tcttcgttcg
   853621 catatggctc tacacgatct tcaatgccgg cctcgagagc ctcttcttcg agggaggaag
   853681 ccttctgtgg ttcacgttca tggtcgcgct ctacggactt tccctgcaat ccagcgcgga
   853741 actcgcggcc gttccggcgc gcgctcgtga ggggaggctc gtgcatgctt gagaggcaaa
   853801 gcaggatcgg accacttgtc gacaggcttg cgaaccgggc gatctggaaa ctggcgcggt
   853861 cgcgccggct cttggaaacg gacgttccgc tcgtctcctt tactttcgac gatgtgcccg
   853921 acagcgcgct tggcgcaggc gccgccgtcc tggagaaata cgaagcccga ggcaccttct
   853981 atattgcagg ggggcttgcc gggcaggtgg aacctgaccg acggctgatc acgcccgaag
   854041 gatgcggcga gctgctcgcc cgcggacacg aaatcggctg tcacaccttt tcgcaccgca
   854101 gattgcgcga tattgccggc ctcggtgccg atctcgaccg caatgacgcc tacctgaagc
   854161 gcgtcggcgt ctcgcccggt gcctcgaatt ttgctttccc ctacaatgcc gcctggccgt
   854221 ccgcacgggc cgagctccgc cgccgctacc ggacctgccg ggcagcgggc gaggctatca
   854281 accgtggcgc cgtagacccg atgatgctga agggtgtcga gatccgccag ccggagcacg
   854341 aggcgcgcgc tttgacaagc tggatagacg atgtcgtcga gcgtcccggc tggctgatct
   854401 tcttcaccca cgacatcgcc atgcagccga ccagttacgg ctgcactccg gaaaccttcg
   854461 accatctggt ccgttacgcc gtcgaaaaag gatgctgcat cctgagagtc gatagcgccg
   854521 ctgaccggat cggctggtga ggaggtccag gtgacccgaa aacgcctcct tgcgatcaac
   854581 aactatttct atcgccgcgg cggcgcggag gcagtcttct tcgaccatat gagcatgttc
   854641 ggcgagatcg gctgggacat cgtccctttc gccatgcagc acgatctcaa cgagccctcg
   854701 ccctggtcgg actactttgt ctcggagata gaatatggcc gtcggaccgg tctcctgcgg
   854761 aaagccgtgc aggcggcgag cgtcatctat tcgctggagg cgcaacgaaa tctcggccgg
   854821 ctgatcgagc gcgctcgtcc tgcggtagcg cacgcacaca acgtctacca ccatctgtcg
   854881 cccgccatct tctccacttt gaaggcagcc ggcattcccg tggtaatgac ggtccatgac
   854941 ctgaagcttg cctgcccctc ctataagatg cttcgcgacg gcaaggtgtg cgaggactgt
   855001 cgcggcggca gggtctacaa cgtgctgcgc catcgctgcg tgaagggatc ggccccgctg
   855061 agcgccgtcg tgctcgccga aacgctgctg caccgcttgc ttggactcta tcgggacaaa
   855121 gtggaccggt tggtcgtacc cagccggttt tatctggaga agctcgccga atggggctgg
   855181 ccgcgcgaaa agatggtcca catcgctaat ttcgtcgacg tcacaaatct ttccgttcat
   855241 cggcaggaga gtgattattt cgcctttgcc gggcgcctgg caccggaaaa gggcctcacg
   855301 accctgatca gggcggttgc cctgtcgaaa cagcggctcg tcattgccgg cactggaccg
   855361 gaggagcagg cccttcgcgg gctagcagcc gaacttgggg cggatgtgag ctttgccggc
   855421 tatctctcgg gggagaggct gcacaggctg atcggcgagt cgcgcgcact cgtcctcccg
   855481 tcggaatggt acgaaaacgc tcccataagc gtgctcgaaa cctacgcgct cgagcgaccg
   855541 gtgataggcg cagcgatcgg tggaattccc gaaatggtga aggagggcga aaccggcctg
   855601 ttggccgctc cggggaacgt cgaagacctt gccagagcgc tacgcgaaat ggcggcactc
   855661 tcgcccgcgg cacgcgcgcg catggggacc gctggccgat cgtgggtcgc gaccgaattc
   855721 tccgccgccg cctaccggga gaggacactc gatctctacg cgggaatcgg tgttgcctga
   855781 gggtggagcc gccttccgtc tgattatcgg tcaattcgct acgaatttaa cgacgatctt
   855841 acagaggtgg taagtcgccc actcgtaaaa gtgcgaaatg ggtcatccct ggggcggaac
   855901 aaccatgagc agaaaatcgg agacctccgg agatcgtcgt ccggcacagg cggatgcgtt
   855961 gactttgacg ggtcgccagg cggcgagagt cgccaagcgc cggcgcgtga tgatgcttgg
   856021 gcttcgcggc atcccgaatg tccagggcgg cgtcgaaaag cacgtggaga tgctttcctc
   856081 ccggctgaca gggcatggct gggaggtcga ggtcgtcggc cgacggcgct atctgccggt
   856141 ctccgggccg catctctgga atggcgttcg cgtctcgcct ctctgggctc cgcgcatgat
   856201 ggcgctcgaa gccattattc atacctttct cggcatatgc ttcgccgcca tgcggcgtcc
   856261 cgatgtcctg cacatccacg ccgtcggtcc ggcactcctc gtgccgcttg cccggctcat
   856321 gcggctgaat gtcgtcgtga cccaccacgg ttacgattac gatcggcaga aatggggcgc
   856381 ctttgccaag aagatgctgc ggacaggcga acggatgggc atgcgcctcg cccatgggcg
   856441 cattgcgatc tcaagggaaa tcgcggagac gatgggcgaa cgctatcgcg tgccggttgc
   856501 cttcgtgccg aatggcgttg ccgtttcgca ttgcgacgtt gaaaccgggg ttctcggcga
   856561 attcgggctt acacgccgtc gctacatcct gcttgcagcg cggctcgtgc cggagaagcg
   856621 gcagatcgat ctcatcaagg cctatgcaaa actgggaaat accggattca atctcgtgct
   856681 cgcgggcggt gccgaattcg agagcgctta cgaagacgag gtaagggcgc tggccagccg
   856741 cgtaccgggc gtcgttctga cggggttcca aaccggcgat cgtctggcgg agctcttcgc
   856801 caacgcggcg ctcttcgttc tgccgtccag tcacgaaggc atgccgatcg cgcttctgga
   856861 ggccatggct cacggcctcc cggttctggc aagcgacatc gtcgccaatc gccagctcga
   856921 cctgcccgcg ggcgactact ttccgcttgg cgatatcgat gctcttgcgt ccgccatttc
   856981 tgaaaagact gccacgtccc tggatgaaca agaggtgctc gcgcagactg aacgcgtcga
   857041 gtcagcctat agctggtcga gcgtggcctt gaagacgctc gatgtctacc gggcggtgac
   857101 gaaatgaatc tccggcggat tgcatccctt cttgcgtggt ctcttctttg cgtcatcgcc
   857161 tattcgaccc tttcgccgct cgacctgcgc ccgcatatgg gcagttcggt gcagatcgaa
   857221 cggttcggcg cattcggcct gacgggtctc atgttcgcgg tcgcctatcc caggcgtttg
   857281 ccttccgttc tggcgatcgt actggcggct gcggtcgggc ttgaattcat gcagatgctt
   857341 gctgccgacc gtcatgcgcg gctgatcgac cttgcggtca aagtggctgg tggtggctgc
   857401 ggcgtcgctg ccggctggct gctcgttcga cagtggcaac gctctcggcc tgagatcacc
   857461 ggaataaacc gacacgcgaa attgcgcgga tagaacgtcg ccgcgacgcg cgatttgggg
   857521 gctctcttga acgtatccgt tatcatcaag acattgaatg aagaaaagcg aattgccgcg
   857581 actatcgaaa gcgcgcttgc ggcgcttgaa aggaccagcg gcgaggtcgt catcgccgat
   857641 agcggctcct cggaccgcac gatcgagatc gcctcgcaat acccggtcgt gatcgcccag
   857701 atcgtgcctc ccgcgcggcc gagctgcggt atcggcccgc agctcggttt tcagcactcc
   857761 cgcaaggact acatctgtct catagacggc gatatgctgc tggacgagac gttcctcgaa
   857821 gacgccatcc gattcctggc cgaacaccct gcaattgccg gcgttaccgg acgtgtcgag
   857881 gaaatgcaca tctcgaatct cgaattcgcg cgccgcgtca gccgcaatgc gcctgagaac
   857941 cggacgggtg cggtcgatcg catgaacgga ggcgggctct acaggcggag tgccatcgag
   858001 agcgtcggct acctttcgga tcgcaacctt cacggctacg aggagttcga tttgggcatc
   858061 cgcctcagga gcgcgggttg ggggctctat cgcctcgatc gccggttcgt caggcacttc
   858121 ggccatacgg tcaactctta ccggctgctc gtgcgccgct ggaaaagcaa gtacctcttc
   858181 ggtatcggcg aacttctgcg ggcatcgctc ggcaagccct atttttttca gctcctgcac
   858241 gagttgccgg agttgaagct ctgggggggc gtttatctct ggtggctagc ctgccttggc
   858301 ctgatcctgt ttctgcccga cacgctcctg gcaatggccg ccgtctgcct gagtttcgcg
   858361 ggtgcggtcc tgctcgttag tttccgaaag ggcggtctca gcatggggct gtatacggtc
   858421 gtcgcctggt ttttccatgc cgccgcgctt cctatcggtc tgctgcgaag gcggcggcag
   858481 ccggcagagc cgatcgaaag cagaattttc ggaacggcga catgagaaga tgtttgctgg
   858541 tggcggccct gctttgcacg tggttcccgg acgcgggcgc ctcagaccag tgggtgcccg
   858601 tccgcgatgt ctcactcgaa cttcgcaccg gcagccccct cgatttttca tccttgctgc
   858661 cgaatgccgc gatcgttgcg gatcggcgaa tcgttgctgg tccgggcggc cggctggcct
   858721 ttgccgaggc tccggaaaag ccggtcagaa tgctgtgcgc ttcgctcgcc tggagccccg
   858781 cttccggcgg tttcccggat cacgaggccg ccgaccgcta cgcccgccaa ttggcgatgc
   858841 acggctacaa catcgcccgg ctgcatttcg tcgatgcgag cctgatgttc ggccggcaga
   858901 gggacttcga tttcgatccc gagacgctcg accgcgtcca ctacctgctg gcggcgttga
   858961 agcgccacgg aatctactgg attatcgacg ggctgtcgtc gtcccgcggc gcctatggcg
   859021 gctatgacga ccgctgggac gcccacggag atctcaagct cgggctgcac ctggaccgtg
   859081 atgcaattgc gcattggcgc gttctgcaag agaagttcct gtcgcgcgtc aatccctata
   859141 ccgggacggc aaccatccgg gacgacgcgc tcgcgctcgt gatccttgcc aatgaaaacg
   859201 gcatcgagtt cgacagcgtc gtgcatgagc ggcccgaaag gcccggctat gatgaggcac
   859261 tgtccggacc tttcaaccgt tggcttttgt cgcgctacgg gtcgacggag gcgctcgcgc
   859321 gcgtctgggg cgttctcgac gccggcgagc ggctcgaaac cgcatcggtg aggctccccg
   859381 ccaaccgcta tgcggacgaa ccacggatgc gcgatctgca agccttcttt gtagagacgg
   859441 aacgcgcctc caccctgcgc atgagcaaag tcctgcgcga tctcggctat cgcggcctga
   859501 tcagcaccta caacaactgg ccgacggtgc agacggccct cagccgccgc gatctcgatg
   859561 ccgtcacgat gaacacctat cacgactggg tcggcggcta ttctcccgga agcgcacaga
   859621 cgcaggacag ctcgcttgcc ggcggcgcca actacatgcg catgatcgcc gcggcgcgat
   859681 ggctcggcaa accctttatc gtcagcgaat acgaccatct tttctggaac cgctatcgtt
   859741 acgaggcagg actggcaatg ccggcctacg ctgcgctcca ggggtgggac gtgctctgcc
   859801 ggcacggcca cgggccgatc gcgctcgcct atggcgaacc ctttgcgcac aagagggcga
   859861 tgctgcccta tgcgattgct ctggacccgg tggcgcgtgc cggcgagacg ctcagcgcac
   859921 ttttgtttcg ccgcggagac gtcgcgacct cggcgctcac cattcccttc gccgttcggg
   859981 gggaggagga tctcagcgac gacatgcagg cgcgtgagcc ggaaaacctg acggatcttg
   860041 cgctcgtcgg gcgcatcggc ctgcttccgg taaacggttt tgaccgcgaa acaggcgtct
   860101 cgcaaccacg tgagcaggac gccggaacaa ttctcgcagc gcttcgcgac catgctgcgc
   860161 tcgcggctga aaaccggacc gatgtcgcga gcggacttta cgaaagcgaa acggggcaga
   860221 tcctgctcga ccgccggatc ggacagctcc gtgtctcggc ttccgcaacg gaagctgcag
   860281 ccttctcctc tttgcgcgag ccgatcgagc tcggtttcat gcgcatcgca caggcggacg
   860341 gaaacgggct tgtggcgatc tcggccatcg acgccgagcg cactctttcg caaagccggc
   860401 gtctgctgct gatctttgcg accgatgccc agaacagcaa catggtcttt cgcgacagtg
   860461 atgagaaggt gatcgaggac ttcggcgagt tgccggtaag aattcgaaaa aactatgtcg
   860521 acctcgaatt gtcgcggacc gccggcaaat ggagcgtgtc accggtcggc ctcgacggca
   860581 ccgtctaccc gcccgtggac aggggcagcg ggcgcgtcgc tttccgtctc tcgaacgata
   860641 cgccctacgg gccgaccacc tattttctcg tggagatgta ggttcagtct gcaacgttcc
   860701 ggtcgcgctc gatggattcc tccagttcgc ccttgcgtgg agcctcgacc gccgcgtgtg
   860761 acgacaggcc ggcaagctta tgcccccttt cccgcagcca ttggaacacg acatagagcg
   860821 ccggaatgat gaaaatcccg aggagtgaag cggcgagcat gccgccggcg acgcccgtgc
   860881 cgaccgcacg gcggctgagc atgccggcgc cttcggccgt gacgagcggc accagtccga
   860941 cgatgaaggc gaagctggtc atcatcacgg cacgaaaacg ggtgcgcgcg ccttcgactg
   861001 cggcatcgac gataggcacg cctttctctc tttggaactt tgcgaattcg actatcagga
   861061 tcgcgttctt ggaggcgaga gcgatcaaca cgacgagacc gatctgtgca tagatatcga
   861121 aggagagccc ggcgaggagc actgcgacaa gagcgccggc cacaccgacg gaaaccgaaa
   861181 gcagaaccgg aattgggatc gtccagcttt cgtaaagtgc cacaaggaac agataggcga
   861241 agaagacggc gagcgccagg atcacagttg tctggccggc ggcctccagt tcctgcagcg
   861301 ccgtccccgt ccactcgaaa ctgtagcccg gcggcagtgt ggcggcggag atttgttcca
   861361 ttgccgcaag agcctgcccg gaggacacgc cgggtgccgg ttgaccgttg agggtgatcg
   861421 agcggtaatt gttgtaccgg acgatcgact gcggtccgac gatatagttt acccgggcga
   861481 ccgaggctac cggcaccatg tcgcctgcag cgttgcgcac atgcagccgg gagatgtctt
   861541 cgaccgcatc gcgatcggtc tcggccgcct gcatcgtgac cttccagctc cggccgaaga
   861601 ggttgaagtc gttgacgtaa taggatccga gcgtcccctg tagcgtagcg aagaggtcac
   861661 ttacggagac cccgagcgcc tgcaggcgat cgcggtcgag atcgagataa agctgcggcg
   861721 agctcgccga ataggtgctg aaggtcggcc cgagttgcgg gttctggttg gcggccacca
   861781 tcaatccgcc ggccgtcgcc gcaagctcgg ccggtgatcg gccctgcagg tccagcaatt
   861841 ggtattcgaa gccggagccg gtgccgagac cgatgatggg tggcaggttg aaggcgaaga
   861901 cctgggcgtt tcggattgcc gcgccttgcg ccatgacggt ggcgatcgcc gcgttgaccg
   861961 aggcggtttc gctctctcgt tccgcgaatg gcttcatcgt cacgatcgcg aaagcgctgc
   862021 tcgacttggc aatgccgtcg aggaagctat agccggtgac ggtggtaacg ttcgccaccc
   862081 cttcgatgct gccgagcagg ctttcgacct ggcgcacgac ggcgtccgtc ctgttgaagg
   862141 atgccccctc agggaggcgg atttccgcga agaaagcgcc ctggtcctcg ctcggaagaa
   862201 agccggtcgg aacgatccgg aacagccagc cgctggcgcc gatcgcgacc gccagcagaa
   862261 ccaggccgag gatggctctg cgggcaatgc ctccggcaag atgggcgtag ccgttacgag
   862321 tgcggtcgat gccgcgcgat atccagccga gaacgccgcg tttcggtccg tgatgcggtt
   862381 tcaggagaat tgcgcacagc gccggactca gggtcaatgc gttgatggcg gagatgacca
   862441 tcgagaccga cacggcgacg gcgaattgct ggaaaagctg gccgctcagg cccggaatga
   862501 acgcgaccgg cacgaagacc gaaagcagga cgagcgtgat ggcaacgatc gcgccggtga
   862561 tttcgcccat cgcaagacgc gaggcctccg ccgcactcat gccggggttc tcttccatca
   862621 cacgttcgac gttttccacg accacgatcg cgtcatcgac gacgatgccg atcgcgagca
   862681 ccagagcgag aagcgagacc gtattcagcg agaagcccat cgccaggatc accgcaaagg
   862741 taccgacgag agccaccgga acagcgatga gcgggatcaa tgtggcgcgc caattgccga
   862801 gaaagaggaa gacgacgatg atgacgaggg caaaagcctc gaggagtgtg tgctcgacat
   862861 tctcgacgct ggcctggacg aagtccgagg tgtcgtagga gacgctatag gtgaggccct
   862921 ccgggaatgc tgcggaaagg cgctccagag cctgttgcac gccctccgtg gcggcgagcg
   862981 cattggcgcc cggtgcctga taggtgccga tcatcgccac cggtttgccg ttgatgcggg
   863041 cagtggagtc tgagctcacc gaccccagct cgacgtgtgc gacgtcgcga atgcggacga
   863101 aggaaccatc cgctccggcc ctcagcacga cgtctccgaa ctgggctgga tcggtcagcc
   863161 ggccctgcgt ctggatgttc agctggaaca gcgggtcatc cgtcatcggt tgggcgccga
   863221 tgcggccgat cgcagcctgg acgttctggg ccttcaaggc gttgatgacg tcggtcggcg
   863281 tcaatcccag attagtcagc cggtcgatgt cgaggacgat ccgcatcgaa tagtcctgag
   863341 cgccgaaaag cgttgcgtcg ccgacgcccg gtacgcgctt gatcgtgtcg agcacgttga
   863401 tcgtcgcgta gttcgagaga aacagattgt cgaattcgtc attctcgccg tgaatggcga
   863461 tcacctgcat cagcgaggag gatctcttct ggacgctgac gccgctctgc ttgacttcgg
   863521 ccggaagcac cggctcggca agtgccacgc ggttctgcac attgaccgtg gcgatgtccg
   863581 gatcggtgcc gacggcgaag gtgaccgtca acgagtaggt cccgtcggcg ccgctcgtcg
   863641 atttcatgta gagcatgtcg tcgacgccga ccaccttgct ctcgataggc tgagcgactg
   863701 tggcctcgac cacgtctgcg ccggcgccgg gatagcttgc cgttatgctg acctgcggcg
   863761 gaacgatatc cggaaactgc gcgacaggca gtctcgtcag agcaatcagt ccggcgaggg
   863821 tgagcacgat ggaaatgacc gcggcaaagc gcgggcgatc gatgaagatt tcggaaatca
   863881 tgttcagccg cccgtcgtcg tggccgtgac ggcatctacg gtaatccccg gccgcacctt
   863941 gccgacacct tccgtgatga cgttctcgcc ctccttcaac cccttggcga cgacggcctg
   864001 accgcggctg gatcgactga cctctacccg gcgaagctcc accttggagt tggcgtcgac
   864061 caccatgacg aatgcaccct gctgatcgcg ctgcaccgcc tgctgcggga ccgcgagcac
   864121 gtcctgccgg tcggactgct cgagaacgac cctgacgagt gtgccgtcga ggaggacccc
   864181 gcccggattg ggaaactggg cgcgcacggt gacggtgtcg gtgccctggg agacggtgct
   864241 ggcgacgaaa tcgatggtgc ctttttgtgg gtactcggtg ccgttaggaa ggacgatgct
   864301 gacattggcg ccgccggaga tctcaccttt ttccacgcgt tcccggtagg agaagtaaag
   864361 cgaggtcgcg actggaaatt ccgcatggat cggatcgagg cgcgtcaacg tgacgagagt
   864421 tccgctttcg ggggtaacga gggcgccgac atcgacggcg gtgaggccga cgacaccatc
   864481 gaaaggcgcg aggattttgg tataggaaag gttgagttcg gccgtctgct tgctgccctt
   864541 gagacgcaat atatcggcct cggccttttt cagctgcgcg ttcgccgtgt cgagtgtcgc
   864601 ctgagcgacc gtgttggttg cgatcagccg ctgtgcgcgg tcacgctcga gaatcgcaag
   864661 gtccctctgg gcctccgccg ccgctatcga accctcgatc tcctgcaggg cggcgcgata
   864721 ggcgccgtcc tccacctggt aaagcgcggt tccggcggag accttctgcc catcctcgaa
   864781 gttaaccttt tcgatgaagc cggacacgcg ggcgcgcatg tccaccttct ggatcgccac
   864841 gaccgtgccg gtcagatcga cgctttcgcg caggtccatg accgcggccg gcgccaccgt
   864901 gacggctgga gggggctgtt gcgcatcagc ggttcccacg acgaagtcgg cggccgccag
   864961 tagcccgcat gaaaggactg cagccaatac cctcgaaacg cgcatgcaac gctccctgaa
   865021 aagctgaagt acgatcccgt gagtgggtta ccgccgatca caccacttcc gttaatacaa
   865081 gtcacgcaac ttgaacttgc cgctgtcctg catgctaacc gtacggtggc gaataggaaa
   865141 ggacttagat cacgatgatt tcaggttcgg atcgcagccg cgacgcgaag atcagtcccc
   865201 ccgcgccccc gtggctacag cgggccgccc gcaacagccg agtgcccgta ggctcccgct
   865261 gctgcagctt cataacacga agtagccctt ctgcaggctg acggcgtcgt ccagatgtat
   865321 cgcgaaatcc gctttcctgt cgccgttcac atcgccgtaa atgtaggtat cagaggcttc
   865381 cctgatatag cggagttcgc cgttcttgcc gccaaaggcg gcagttccaa cgaagtgaaa
   865441 tgccttgttg ccgacggccg atatatcggc gtcgatcaca gaaagatcga accggtctga
   865501 ttgtgcggtg taatcgtaaa tcgtatcgcg gccggacctg gagacggtcg aatccgagag
   865561 cgccttgaaa acgaagctat cggctccgct gccgccgttc aaacggtccg cgcccgcgcc
   865621 ggcatagagc aggtcgctgc cgctttcgcc gaagagcttg tcatgacctc tcccgccgta
   865681 aagcttgtcg gaaccgggag gcccgcaagg cgatactgcg tctgcaggag cggtgagtga
   865741 gcggcgctat ttcgcccgca gcagcatccc gaacaggtcg cgggggtcgt ccggatcggc
   865801 gatcatgtcg aggttctggt aaaagtcggt gccgggaagg cgctcgcgca catagcggag
   865861 cgcggagaag tcctcgatgg cgaagccgac gctgtcgaag agagttatct gacgggcgtc
   865921 ccgccggccc tgcatctcgc cggtaacgac cctccagagt tcggtgacgg gaaaatccgg
   865981 ttccatctgc tggatctcac cttcgatccg ggtttggggc ggatattcga cgaacacgtc
   866041 cgagcgcttc aggatgtccc gatgcagttc cgtcttgccg gggcaatcgc cgccaattgc
   866101 attgatgtgg acgccggtgc cgaccatgtt gtcggtcaga atcgtggcaa attgcttatc
   866161 ggccgtgcag gtggtgatga tcccggcgcc ctcgatcgcc tcctgggcgg acctgcatga
   866221 aacgatcgtg agaccggcac cgtccaggtt gcgggcggcc ttctgcgttg cccgtgggtc
   866281 gagatcgtaa aggcggacgg tgtcgatgcc gcagacggac ttcatggcca gcgcctggaa
   866341 ctcggcctga gcgccattgc cgatcatcgc cattatgcgc gcgcccttcg gagccagatg
   866401 gcgggcggcc attgccgagg tcgcggcggt tcggagcgcc gtcagtatgg tcatttcggt
   866461 gagaagtgcc gggtagccgg tcgaaacctc ggcaagcagc ccgaaggcag ttaccgtctg
   866521 gagcccctcg gcggtgttct tcgggtggcc attgacatat ttgaaactgt acaccctgcc
   866581 atcggaggtc ggcatcagct cgatgacccc gtcgcgcgaa tggctggcga cgcgcggggt
   866641 cttgtcgaag ctctcccagc ggcgaaagtc cgcttctatc gcatccgtga gctccgccag
   866701 gaccgtctca atgccaaggt gatgcacgag gcgcatcatg ttgtcgacgc tgacgaaggg
   866761 taccatggcc ttggcagacg gaagcggtga gagcatcgag gtttcctctt cacggtgctg
   866821 gattccagat aggttaccga ttgagcccgc tgttcgaaag cgcaaacatg tgctatttta
   866881 ggcacccgtt taagcgattt gttcaattgg attgtgcaag atgagcagaa gagcagtcag
   866941 ggactcggcc gttgcgaaat acacgcctga tgacctggat cgccagataa ttgcacatct
   867001 gcgctccgac gggcgggcct cgctttccaa gctctccgat gcgttgggcg tggcgcgggg
   867061 cacagtccaa aatcggctgg aacgcctgct cgagaccgga accctcctcg gattcaccgt
   867121 ccgggtcagg gaagactacg acgtcagcac ggttcatgcg gtgatgatga tcgaagtggt
   867181 ggggaaatcc acgacgcagg tcatccgcag gctgcgcggc ttgcccgaga tctatacgct
   867241 gcacaccacc aacggcaact gggatctggt tgccaacatc cgtgcggcca acctctcgga
   867301 gtttgatcgc atattgcgcg aggtgcggat gatcgatggc gtcgccaaca gtgaaaccag
   867361 tctcttgttg agcagcgtat gatctgcggg cgcgcgagca gaccggatga ttgaaagccg
   867421 gacctttccc cgttaggttc cgcgcgcatt catgatttcc aagggggcgg gcttggcgag
   867481 ccgtaagatt tgttttctgt tggcctgcct aaccgtcatg ccggcgacag cactggcgga
   867541 gtggcaggca gtcgagaaga tcgagactat tccatcaccg gacaatccgg gccggaactc
   867601 tacgccgcga tcggcgaacg gggaccgcgg gtggggggcc tcgggcgcgc gatcgctcat
   867661 acgagcttca agctcacctg gaggcggaaa tacgaggagc gagacggcgc ctgtgtcctc
   867721 gcctccgcgc tgccgaagct gaccatcacc tacacgctgc cgaagctttc cggcaagctg
   867781 tcgggcaata ccgaagcgaa ctgggaaact ttcatcgacg gcgtgaaaag gcatgaacgg
   867841 gtgcacggcg atttcatcaa ggagatggtg agtgcgatcg aggtcgcgac cgtgggcctc
   867901 actgtcgccg acgatcccaa gtgccgcaag atcaaatccg aaatgaccaa gcggctcggg
   867961 gaactctcgc gcgcgcaacg gcagaaaagc cgcgacttcg acaaggccga actcagcgac
   868021 ggtggcaaca ttcaccaact gatcctcaat ctcgtcaacg gcggctgatg catctggctc
   868081 gattgccgac ggctcgatct tggccaaatg gcaacacccc gcagcaaaaa ataagtcgtt
   868141 ggcggccctg cctctgaatt gtctcaatgc aacgaaagcg tgagcccgcc tgacagggca
   868201 ggcacgggcg cacgaaatct tacgcgcgcg ctgccattac tgaatttgtt tcggaccgcc
   868261 ggctgcaatt gctgccggtg acgagccgac gaggagaaga tgcatgaaaa agactctcgc
   868321 catggcgttc tccgcggtca cgatcgcgtt taccgctgcg ggcgccaatg ccgctgatct
   868381 gacctatcag gaaccggctc cgccgcccgc ggttcaggac gcgcggggcg gtgtgaagat
   868441 cggatacttg gaatgcgaca tcggaggcgg tgccggttat gtgctcggat cctccaagga
   868501 ggtcgagtgc tttttccggt cgttgggcgg cgatgtgatc gaggatcgct acacgggtga
   868561 aattcgcaaa ctcggcgttg acgtcggttt caccatgcgc agccgattga tctgggccgt
   868621 attcgcgcct acggcgggtt accaccatgg ttccctgagc ggcatctaca agggcgcgac
   868681 ggccgaagcg acgctcgggg cgggcgtggg agcgaatgtg ctcgtcggcg gcacctcagg
   868741 ctcagtccat ctccagacgg tcagcgtcac gggccagctc ggcctcaacg tcgcggccgc
   868801 cggcacgtcc atgacgctca actcggcgaa ctgaccttcc tccggcgcgg ccatcacgcc
   868861 gcgccggagt tcgatttccg cgccgagcgc cagaaaatca ccagcattcc cgccgtcatg
   868921 gctgcgagac aataccaggt caacgcgtag accaggtgat tgttgggaaa gacgacgcgc
   868981 gtcagcccgc cgacgggaag cgtcccagga atggaagacg cgtcggcatc gacgaagtag
   869041 ggcgcaacgg gggaaaggcc ccgcgctgcg gctatggcgc cgacgtcgcg cgagtaccaa
   869101 cggtcttcgc ggggtctgtt cgactggagc agagaacctt tcggctcgtc catgcgcatc
   869161 agcccggtga ccttgacctc gtcttcgatc cggccctgct gacgcgcctt agggtcgcgc
   869221 cgctccattg gcacgaaacc gcggttcacg agtacgatcg tgccatcgtg aagcgcaagc
   869281 ggcgtcatga cccagtagcc ggcaccgagt tcggtcgcgg catagaccag cgtttcctcg
   869341 tcgttgagaa agcggccatg cagcgctacg tgccggtatt cgtcgcgtgc cgggctgaca
   869401 ttcggccaat cgcttctggg cggtgcaggg acggggggag caccgatgcg ttgttcgacc
   869461 cgcgcgataa gatcgagctt ccagaagaga cgcttgacct gccaggtgcc gagcgcgagc
   869521 aggccggcga tcaacaggag accgagaata ctgaccactg ccagccgcga gcgcgggcga
   869581 aaggcggttt cgttttgcaa gtcggtcatg atgcggttca aacgcgaagc gcgctgtctc
   869641 aacaattaag ccttaatccg gctgccgcac gccttcaccc gatggagggg agggttggcc
   869701 agtcccacgg tcagggcatg ttcttcatca tttccgggct catcggcatc atgttggtgt
   869761 tcagatgatg catgacccag agcgagccgg aaagtgcaat ggcgacgagg acgatggtga
   869821 agatcagcgc catcatcgtc catccgcctt ccgagcgtgt gttcatatgc aggaagaaga
   869881 tcatgtggac gacgatctgt atggcgccga gcgccatgat gatcgcggcg gtgagaatgg
   869941 cgctttcgag cacgtcggcc atgaccagcc agaaggggat ggcagtcagg aggactgaga
   870001 gaatgaagcc ggtcacgtag ctcttcagcg tgccgtgacc cgcgccgtga ccatggctgt
   870061 gaccgtgatg cgcctcgaaa gcgtcctcgt gcgaagatgc atgtgtgctc atcgaagaac
   870121 tcccatcaga tagacgaagg aaaagacgcc gatccagacg acgtcgagga agtgccagaa
   870181 catcgaaagg cacatgaggc ggcgcttgtt ctccgcgatc aggccgtgtt ttgcgacctg
   870241 cgccatgagc acgaacatcc agataatgcc ggagctcaca tgcagcccgt gcgtgccgac
   870301 gagcgtgaag aacgacgaga gaaaggcgct gcgctgcggc ccggcaccct cgtgaataag
   870361 gtgcgcgaac tcatagagct cgaggccgac gaagacgatg ccgaagaggg cggtgaccgc
   870421 catccaggcg agcgtcgccc gcaaccttcc cttttccatt tccagcatgg caaagccgta
   870481 ggtgatcgag gagaagagca gcatcgacgt gttcagtgcg ataagcggca ggtcgaagag
   870541 atcggcgggc gaggggcccg ccgcgtaatt gcggccgaga accgcgtggg tcgcaaagag
   870601 tacggcgaag atcaggcagt cgctcatcag atagagccag aaaccgagca tcgtgctccc
   870661 ttccggatga tgctcttcct tcagatagaa tgcaggcgcc ttgccctcgt ggagggcgtc
   870721 agaggagtga aactcgttca tgcttgcacc tcagcggcaa gctcttcggc gcgcttgccc
   870781 tccgtgtcgg cgacgacatt tgcgggaatg tagaagtcgc ggtcgtagtt gaaggtgtga
   870841 ccgatggcga tcaccaccat cgcgacaaaa gacaggatcg ccagccacca catgtaccag
   870901 accatggcaa aggcgaagac gacgctgatt gccccgagga tgacgccggt gccggtgttt
   870961 ttcggcatat ggatcggctt gaaaccggta agcggacgct catagccgcg cttcttcatg
   871021 tcccaccagg agtcctgatc gtgaacgagc ggcgtgaagg cgaagttgta gtccggcggc
   871081 ggcgaggcaa tcgaccattc gagcgtgcgg ccgtcccagg ggtcaccggt catgtcgcgc
   871141 agcttctcgc gattcatgaa actgacgacc agctggatca gcatcgacag gataccaagc
   871201 gcgatcagga aggcgccgaa tgccgcgatg acgaaccaga tctgcagcga agggtcctcg
   871261 aactggctga cgcggcgcgt aacccccatg aggcccagca cgtagagcgg tatgaaggcg
   871321 aagtagaagc ctatcagcca gaaccagaag gacatcttgc cccagaacgg atcgagcctg
   871381 aagccgaagg cctttgggaa ccagtagacg acgccggcca tcagcccgaa gaccacgccg
   871441 ccgatgatga cgttatggaa atgggcgatc aggaacagcg aattgtggag cacgaaatcg
   871501 gctggcggca ccgcaaggag aacgccggtc atgccgccga gtacgaaggt caccatgaag
   871561 ccgatcgtcc acagcatcgg cacctcgtag cggatgcggc cgcgatacat ggtgaagagc
   871621 cagttgaaca tcttcgcgcc ggtcgggatc gagatgatca tcgtggtgat gccgaagaag
   871681 gcgttcacgc tggcgcccga gcccatggtg aagaagtgat gcagccagac gatgtaggag
   871741 agaatggtga tcaccaccgt cgcatagacc atcgatgcgt aaccgaagag ccgcttgcca
   871801 cagaaggtcg cgacaacctc cgagaagatg ccgaaggccg ggaggatgag aatgtagacc
   871861 tccggatgtc cccagatcca gatgaggttg acatacatca tcggattgcc gccgaggtcg
   871921 ttggtgaaga agttggtgcc ggcgtagcgg tcgagcgtga gcagcgccag tgttgcggtc
   871981 agcacaggga aggtcgcgac gatcagcaca ttggtgcaga gcgacgtcca ggtgaagacc
   872041 ggcatcttca tcatcgtcat gccgggggcg cgcatcttca cgatcgtggc gatcaggtta
   872101 atccccgaca gcgtcgtgcc gatgccggct atctgcaggc cccagatgta atagtcgacg
   872161 ccgacccccg ggctgtagtc cgcgcccgag agcggcggat aggcaagcca gccggtgcgc
   872221 gcgaactcgc cgacgaagag cgacagcatg atgatggccg cgccggccgc cgtcatccag
   872281 aagctgaaat tgttgagaaa ggggaaggaa acgtcgcggg cgccgatctg cagcggcacg
   872341 acgaagttca tcagccccgt cacgaaaggc atcgccatga agaagatcat gatgacgccg
   872401 tgtgcggtga agatctggtc atagtgatgc ggcggcaggt agccttccga accgccgaag
   872461 gccatcgcct gctgcaggcg catcatgatc gcgtctgaaa atccgcgcag cagcatcacc
   872521 agcgccagga tgatgtacat gatgccgatc ttcttgtggt cgacgctcgt cagccagtcg
   872581 tgccagagcg tgccccagaa gcggtaatag gtgatgagcc ccgtcagcgc gatgccgccg
   872641 agcacgactg cggcaaaagt cgcgacgagg atcggctcgt gataggggat ggcgtcgagg
   872701 gtcagccggc cgaagatgag cttcagaaga tctggatcgg agaacatggg aaacctgttc
   872761 atttgcttag atcacgatgt tttcgggttg gatcgaccta aaaacataaa cgtgattgat
   872821 tccaataagg tagagcggga tgcgggcgga aaaccgcacc cgcttttcct catcccgctt
   872881 cagcgcgcag cgcccgtatt caatgattga gctgagccgg tgccggatcg ttttcatgat
   872941 cgctctcatg attcatgcct ggcattgagt gtccctggtg tgctcccatg cctggcatag
   873001 ggtgctgcat cggctgttcg ccgccgcccg tgccctgcgg ttcctgctgg ctgcgcgccg
   873061 gcgtgcccgt cgcggggtgc gtcgcggccg gcgcgccttc cgctagggaa tgcctgttgt
   873121 cgtattccag cttctcccgg tttccggcgc tctccttgcc ggcaccgccc atcatgtcga
   873181 tgtgcatcat ctgctgcatg cacatcttgc cgggtgtgac gcatagattg agaatagccg
   873241 tatacaaccc gtcctcgacc ctggcgaaat agcggaccgg ctcccgctgg ctcggctttt
   873301 caagcttcag ataggtgtcg cggttcagcg cggtgccttg cgtcttcacc cgcgacaccc
   873361 attcctcaaa gccctgccgg tcaagcccat ggaacttgaa gcgcatatgc gaaaagccgt
   873421 cgccgctgta gttggccgag aagccctcgt attcgccctg cttgttgatc accgcgtgca
   873481 gcttcgtttc catgcccggc atcgcataga tctgaccggc aagcgccggg atatagaagg
   873541 agttcatgac cgacgaggcg gttatcttga agtgaatcgg gacgtcgacg ggagcggcga
   873601 gctcgttgac cgtcgcgacc ccgagctcgg ggtagaagaa cagccacttc cagtcgagtg
   873661 cgaccacctc cacggtgagc ggcttggcgt ccgcaggtat cgccctttcg gcatccagcc
   873721 ggtcgagcgg ccgataggga tcgagtttat gcgtgctgat ccaggtgatg gcgccgagcg
   873781 cgatgatgat cgcgagcggc gccgaccaga tcaccacttc gagcgcggtc gagtgatgcc
   873841 attccggatc gtaggtggcg ctggtgttcg aacgccggta ccgccaggcg aagaaaagcg
   873901 tcaggaagac caccggaacg atgatcagca gcatgaggat cgtcgagatg acgatcaggt
   873961 cgcgttgctg cgcagcgata tcgcccgatg gcgacatcac caccatgtcg catcccgcca
   874021 tcagaagaaa cagcggcaaa acggcgaggc ggcgggaaaa cttcaacggt tctggcacgg
   874081 ctcgaagctc tatttgtttc gacggccctg cgactaaagt agagtggacc ggaaaggtat
   874141 gaggtcgata gtcgcactgc agcaatccgc cgcagccggt gatgcatcgc agcatgtgag
   874201 ggccgggtcg cgattggcgt cctgaaacgc gttttttccc gtatcgcccc ttgatatgag
   874261 ccgttgattg gtcaagatcc ccattgagag agcttcgcgc tttcttctgg agagttcgag
   874321 cgagatgcgg cggaacatcg catgttccaa gtcccggtcg accgcgggag gcgttttcga
   874381 tgaatggtgc aattcaacaa tccctgggac cgtcgtcctc ctcgatggag cgcgatgcgc
   874441 ggcgcattca cgacgacagg ccggtatctg caggcaacat agccattggc gtcgtgatcg
   874501 gccgcgcagc ggagttcttc gatttcttcg tttttggcat cgcctccgtc gtcgtttttc
   874561 cgcagctctt ctttcccttc gcgcccgacc ggctgaccgc tacgctctat tccttcgcca
   874621 tctttgcact cgccttcatg gcaaggccgg tgggttcgct ggtcttcatg gccatcgacc
   874681 ggacctatgg ccgaggcgtg aaactaacga ttgccctttt cctcctcggc ggatcgaccg
   874741 cctccatcgc ctttctgccc ggctacgcaa cgctcggcgg ctggtccatc ctgctgcttg
   874801 ccgtcttccg tctcggtcag ggatttgcgc tcggcggggc ctgggatggg ctcgcctcgc
   874861 ttctcgccct caacgcgccg cagcatcacc gcggctggta tgcgatgatc ccacagctag
   874921 gggcgccgct cggcttcatg ctggcgagtg cgctgtttgc ctacttcctc gcttcgctct
   874981 cgcaagcgga ctttcttgcc tggggctggc gctatccgtt cttcgtcgcc tttgccatca
   875041 acgtcgttgc attattcacg cgcctgcggc tcgtcatgac gaaggaattc ggaaccctgc
   875101 tcgatctgca cgagcttcag gcaagccggg tcacggaggt gctcagagta aatggtgggc
   875161 acgttctggt cggtgcgttc gtgccgcttg caagcttcgc tctcttccat ctggtgacag
   875221 tgttcccgct gagctgggtg gaaatataca cggatcacgg cgcaagctcc ttcctgatgg
   875281 tacagttcct tggcgcggtg tgcgggatcg tcgcgatcgt tgcttccggg ctcattgccg
   875341 atcgcatcgg ccggcgcaat catcttggta tgtgcgcggt gctgatcgcg attttcagct
   875401 ttgtagcccc aatgctgctt cagtcgggcg cgaccggtcg cgaaatgttc gtgattgtcg
   875461 gcttcacaat cctcggcctc tccttcgggc aggccgccgg ggcggtcgcg tcgcgcttcg
   875521 gcagggccta ccgctatacg ggggcggcgc tgacctcgga tctgtcgtgg ctgatagggg
   875581 ccgggtttgc accgctggtg gcacttgggc tcaccagtcg cttcggcctc gctttcgcgg
   875641 gatattacct tctctcgggc gcgctttgca cgatactggc gcttatcttc agcaagacgc
   875701 tcgagatcaa caacgaatag ccatgaattc aatcatggag ccgccgctgc gttccccctc
   875761 gattgcgatc ccttgtatgc gcccagcggc ttatgcgtct taggcaaaac ccagcccagt
   875821 agcgcggaac ataatcgggt ctcgccggtt ccggcagcga cgcacattcc ggtgcagtca
   875881 agcacgaaag gaggaagcag tgcctgcgaa atcgaaggcg cagcagatgg ccgccggcgc
   875941 ggcgcttgct gccaagcgag gcgagaagaa gaagagcgaa ctcaagggcg cctctcgcag
   876001 catggaagat tccatgaccg agaaggagct tgaggaaatg gcgtcgacca agcgcaaggg
   876061 aaagaaggaa cacgtctcga agaagtgatg gcgcatcaat agcgcctccg aaaaggccag
   876121 cgcgaacctg ctgacctttg agccggaagg gatctgccgc ttgcagaact cgccggcaca
   876181 aggtattcgg gcgggcataa agttcccggt ttcctactag ggtcggaaga atgtttcagg
   876241 ttgagatggc tgcagccctt tcacacccgc cgttttgatg atgtaaagcg cgaaacagga
   876301 acaatattct gtagcgagat ccgggtcgtg actaaggacg ggcgaatgaa cgatagcaag
   876361 gtttccgcgg atgagaacgc ggaaaaaacc gttgacgagc ggattgcatc gctcgtcgag
   876421 aagatgcgca aggaagcggt gccagagcgt cttctcgaac tggcccggga actgcaaaag
   876481 gcccttgacg agcggaagcg ctgatcagat ctgctcgccc ctataccgtc agttcagcgg
   876541 atttccgtgc atttgcgcag tcagttcatc acgggccctg ctgagccggc ttttgatcgt
   876601 gccgatcgcg cagtcgcata tgtcggcggc ttccttatag ctcaggccga atccggcaac
   876661 gagcacgaga acttcccggt gctccggtga aagggcgcca agcgcgttgc gcaactcgcc
   876721 attgaggacc gaccactcct gcgagggcgc cgtcggtatc ggcaattcag cgcaattggt
   876781 gctcccagga ctttcgcgcg tgcggatttt gtattgcgtg cgaaaggcat tgcgcatgat
   876841 cgtgaacagc caggacttga ggctcgtccc gggctgaaac tgctcgatgc ttctcagcgc
   876901 ccggagcaac gtctcctgca cgaggtcatc ggcctcgaag gacgctgtcg taaacgtacg
   876961 agcgaacgcc cgcagagcgg ggatcagatc gacgacttgc tcctcaagca gcggtgattg
   877021 ttgcgatgcg tgaccgccga tagcaggcat gtcgaatatt gcccttctgc ttatgagatt
   877081 tctcttggtg acgttacaaa atgcctgtcc ggctctttgg ttcctgaagg cgcggggata
   877141 tttcctgccc gcttcattcg ggcatccccc cgcagggctg tgccagcgcg cagatgcggc
   877201 cagctccgcg cgtgccgcga cgggaaccaa aaaggacatc accagtttga gtggtctagg
   877261 gacatcatca tgtttgagtg gaaggagaac gccatgaata gatttgccac tttgactgct
   877321 gccctgtttc tgggatttgg ctcggcggcg attgcgcaga cgacagtggt gctgccgggc
   877381 gaagtaagga cctatgtgct ggagcagaac acgccttctg tcacctacga gggtgagatt
   877441 gtcgtcggcc agccgattcc tgaaacggtg gagatccaca ccattccaga gcagcccgat
   877501 ttcgcctatg ccgtcgtgaa tgatcggcgc gttgtcgtga atccgaagac acacacggtc
   877561 gtggaagttc tggaataatg ccggcatagg ggcgcagcac gcacgcgcga gtctgctttc
   877621 tgcgcttcat gtccccagta tcacgagcgt ggcggctccg ccgccacgcg acggtcggga
   877681 gctgtcacgc caggggctgg acatggaaaa caatagcagc gagtttcgac tggcggcaca
   877741 gagagaaatt ctcgtggccg tcctttccgc gctttaccgg cacaaggatc tctggcggga
   877801 gatcaaacgg gccctcgaag aggtcccgat cgttcaggat catgaagaag atcccggcat
   877861 cgtaccgtcg gaggcttttg ccaggcagaa tgcgatgacc tcggaaattg cttccatcct
   877921 tgatgatgca caggcgcgat cggatctggg tccggagacg cgttgagacg tcaaggtgag
   877981 ttgcgcgcca gatcaagatt ccggaacccc tttcagcttc atgcgttaac ggaaaggctg
   878041 cgttttcagc cccgcatgtc cacgcaagag aagggagcgt atcgtgcgcg ttcgactgag
   878101 acagaagcgt ccgacatttg cccggcctcc ggaaaatccg aacaagcccg gccgcaacac
   878161 gtggcaccca caggtaatcg cccctcagag ggtcgacctc atcctgagga agccgagaag
   878221 agatgaggtg gcggtaccgg cctcgatcaa cgggaggagc ctcatcgatg gccggccatg
   878281 acgataggat ggtccgcgtc cgggacgtga tgtcccggca ggttttcacc gtgtcaccca
   878341 ctgacagcgc gcaatccgtc gcccggctga tggctgagac gggtgttggc gcggtgcccg
   878401 tggagacgcc gggtgtagga acgatcctgg gaatcgtcac ggatcgggac atagtcacgt
   878461 ccgtcgtcgc gaaaggcctt tccagttcaa cggccgtttt cgaattcatg acggtgtcgg
   878521 cagaatcttg cgaggagcac gacagcctcc tccttgctgc tcagaagatg cacgatctgc
   878581 gtattcgtcg tctcgtcgtt gtcaatgaga agcggcaggc cgccggcata gtggctctcg
   878641 ccgacatcag ccgagtcaac ccggaactcg gcggcctcgt tctcgaggga atcaatcggc
   878701 ctgtgcccgt tgagtcacgt cttgaaggaa tgtcaacatg ctgacgcagg atcgtctttg
   878761 gagcgaagcg gtgatcttgg agggcgggaa gaaccgagtg ctcagagtac aaagcacccg
   878821 cgacgcgttt ctctgcctca agaatcattg gccgattgcc gacggagacg caaagcgtga
   878881 cgcctttgca gcctgtgagc gggttatcga gggaaacgac gagcccgata ttgcacgcag
   878941 cgccttcatc aaggctgccg aggaagcgaa gttcagcgta cattcctgga ccggttgacc
   879001 gagccgtctc agctctgaac ggttgggcgg ctgccagacc gtaatttcac cgctgtcgag
   879061 ggccggagcg gttccggctc gccggctcgt tgtaacgctc cgccattgca gcctggactt
   879121 ccgcctgaaa agcgaggact tcctcgcgaa cgccggcctc atcgacgccg agaatggcaa
   879181 gctgttcggc gagcctgcgg cattcgccct tccagtaatg gacggcagcg gcgccatgta
   879241 tcctgtcgag ttcgcgtgcg cagcgtgcga cgtcgcctgc acgggccgcc aagggaaatg
   879301 cgatcacttc gccgccctgg accatggttc cttcgccaaa ctcagctgcc atcgaatcac
   879361 cttacattca tcaccagcca cgtctatcgg ctagatggtt aatgattcat tggtcgcaac
   879421 ggctcgcagt tccgacggat atcgctccgg ttggcgaaat tctcgccgcg acgaacttta
   879481 cagggtgtcg gcgggaacaa acgcttccct gcacagtttg actatcggat cgcgtggaac
   879541 aagttccctc tccgcaaagc cctacggatc cgcgcgttct taaaaacaac gaacaaaata
   879601 acgggctccg ccgtcccagg cggggccttc cttttcgaag ggcgaccgat tcactgtatc
   879661 aatcggacgg catcactgtc gggagtttat cgcaggagac cctggccgcc gtcgatccag
   879721 actgggcttc cggtcacgtg gcgagcgcgg tctgagacca ggaaacggat gacctccgcc
   879781 acgtcttcgc tgcgccccgg ctgcccgtcg gagataggca cctgtccgtc cggccattca
   879841 acgggaatgg ccgtctcttc ttcgtggcgc agtttcgtat tgtcgtcgat gttcgtttcg
   879901 atctcaccgg gacagacagc gttgacgcgg atgtggtgtt tgccgagctc gagcgccaat
   879961 tgctggacca tcgcaacctg tgctgctttg gtggcggtat aggctgtagc gccgggcgtc
   880021 gtaaaggtcc tcgtgccgtt gatcgaggaa acaaccacga tggacccgcc gccgcgctgt
   880081 ttcagatggg ggacggtcaa gtgcagggtg agaaaggtgc cgcgcagatt gacggcgatc
   880141 gtctcgtccc attcgaacgg cttcaggtcg tcgatcggag cccagactcc gttaataccg
   880201 gcattcgcga caacgatgtc gagatgaccg aacttgccga cgaggccgtt gaccgcattg
   880261 cgcatctgca gttcgtcgga aatgtccgcc tcaagcgcca tcgcctcgcc gccggccttg
   880321 gcgatttcgc cggcgactgt ctcaacctcc gatcctgtgc gccccagcgc tccgattttc
   880381 acgccgtcca aggcgagtgc cagagcagtg gctcggccga tgccggaccc ggcgccggtg
   880441 accaaggcaa cggtggatgt tcggttcatg gcttaccgtt cttagcgcgg tcggtcggga
   880501 tggtggaaac ggtgaccgag accggatcac tggccgggaa tgtgtcctcg aggccctcgt
   880561 cgagctgcct ttccatttcg tccgtgtcct tggcaccgcg ggcgctgcga tggaattccg
   880621 ggctgttctg ggactcctcg atcgcgtcgc aatcggcgtc tgcgagctcg cgcatgacgg
   880681 cttgcgccct ttcgatggca ttgagccggt tgatgttcgt ggccgcatca ttgcgcatgg
   880741 atacggagac gatctctcct ccttcgccga cgaattccac cgtaaaaccg gctttcccgc
   880801 cctgttccgg gatgacctgt gtaccaacga gatgcataag gcgtctcctc tcacgatgcg
   880861 ctgcagcatt gcgccgaatt ggctctgtgg ttgccgtggt ttcgtcaggc aaacggctgc
   880921 cgcgtgtttt ggttccgatt agctcttccc agaccccggc gttccgcggc gctggatacc
   880981 ttctcccgaa gttcgtcgtc gtcctggtcg tgggcgtgtt tccggaggat ctcggccagt
   881041 cgtttaagct ctttttcatc cagcttttcg attccgacat agcggttctc cgccgagctg
   881101 gtgaggatga gttcgtcgag ctttgcctga agggcccggc cgtcccggtt ctgcgtgttc
   881161 tgaaggacga aaaccatgag aaaggtgacg atcgtcgtgc cggtattgac gacgagctgc
   881221 cacgtctggg agaaaccgaa gatcggacct gtgactgccc aggcgcctat caatgcaagg
   881281 gcaaggacga aaacggcggg gcgcccggca tattccgcca ccgcgctggc aaacctgctg
   881341 aaaccattgg cctttggcat cggataccca cgtttgttga tccgctgttc aacacgcaaa
   881401 ccctgccaag agttccaatt cctgcatctt gagtgagtgc ggccgcatgc ggtgcggggt
   881461 tcaggtcacg acattgacct gggcctcttt cgccgccgcg acaaaggccg ccctcgccac
   881521 ataggcgggg gagtcgcggt cgagcaccgc ccggcatatg tcgattgccg ccagataggc
   881581 ctggccatgg ctggtcggcc agtgctgcgt cagtagctcg aatgcctgac gggtgttgga
   881641 taccatgtga atctttgaat tatccggcat ccgcacgggt acacattcat tccaggggcc
   881701 ggggtccatg accaccctcc tgcagtggcg cgaccgtcag gaaggcttca cgtaaagcgg
   881761 cgatgaaggc ggcgcgcgcg tcttcaggcc tctttctacg cttgagtgct gcgttgcagg
   881821 cgcgtattgc gcaaccgtaa taggcaccgt cccgcaccgg ccattcgctt tgaagacaat
   881881 gcatagcgtc gagcgggccg acaacggtgc ggcatctgcc gtcgagcatg gtgattttga
   881941 cgggcctgct ccatggaatc tcgtacattt ttcttcctcg ccagcccgga gccgcccagc
   882001 gcgcctcctc catcccgctc taatggctgc ggatcgatat atgtgcctct tccgctgcct
   882061 ttatgaaggc cctgcgggcc ttctccgctc caaccttgcc ttcgagagcc tggagacaca
   882121 cccgcttcgc cgcggccagc gcgcggccgt cccgctgcgg ccagcgctgc gacaggcatt
   882181 ctacggcctc ccgcgtgctt ttcacgtcgc gatatttgcc ttcggctccg agttccagtt
   882241 caacgctctt atcccaccag aaacaatgca tgacgccaag cctcgcggtt gttgccggtc
   882301 ggaaataaaa cttgggacat aggcttttgg ttccgccgca agcgcgcggc tgcccccttg
   882361 acgcacagcg cggcatcgct aagtaagaag cgtcccgctc ttggacatcg gaatgcggga
   882421 tgaacattgg tgccgggccc ctctggcgag agtttacggc gctctcgcga tgtcggtacc
   882481 gccagcaagt cacgccggcg ggtatagcta ccatgaaaac tgatctcatg cctcacgcat
   882541 gtgccaatag gcttgtgcgc ttttccgctt ccggaaattt ctcttatgcg aacgcttcca
   882601 tgatgcgtgg cggggaggtt cgctcatgac cggaggcagc acacagacaa gctctctcgg
   882661 atacttcaaa tgggcgttca tcgttacggg tgcagggctt ctgcttggcg cctggctcgg
   882721 ctggcagtcg accgggaccc tgggcggtat gatgacggtg ttcttcatct gcaccgtgct
   882781 cgcggtcctc gaaatctcgc tgtccttcga taatgccatc gttaatgcca acaagctcaa
   882841 ggacatgacc ccggtctggc agcagcgctt cctgacgtgg ggcatcctca tcgccgtttt
   882901 cggcatgcgt atcgtgttcc ctttgttgat cgtggtcatc gccgcgagca ttggtccgat
   882961 cgaggcggtc attctcgctg caacgcagcc cgaggaatat tcgcgcatca tgcacgaagc
   883021 gcatctcccg atcgctgcct tcggcggtac gttcttgatg atggtcggac tcacatactt
   883081 tttcgaccat gaaaaggacg tgcactggat tgcatggctg gagagccgga tggcgcgctt
   883141 tgcgaccatt aagggagtcg agatcgcctt cgttctggcg ctcatactcg gcttttcgaa
   883201 gttgctcgaa gcggatgaag ccgtcgtgtt cgttcatgcc tgcgtctacg gcctccttac
   883261 cttcctggcc gtcgaagtgg tcggcggcct acttgacgct tcgcagcaga cgatgagcgc
   883321 agcggcgaag ggcggatttg gcgctttcct ctatctggaa gtgctcgacg ccagcttttc
   883381 cttcgatggg gtcataggcg ccttcgcttt gacccagaac cttttcatca ttgccatcgg
   883441 gctcggtatc ggcgcgatgt atgtccgctc catgacgatc atgctggtcg agaagaaaac
   883501 gctcagcgaa tatcgttatc tggaacacgg cgcattctac gccatcctga tcctttccgt
   883561 ggtcatgtat ttccagacgc tggtccatat tccagaggtc attactgggc tcggtggggc
   883621 cggcctcatc ggcctttccc tctggtcctc ggtccgacat aaccggcggg aaatggagca
   883681 ggtcgaggac gacacgcgcg gacggaggcg cgtcgaggcc tgagccaccg cgaccgcctc
   883741 ggcctcgcaa cgagagcaaa gacccggcgg gttacgccgg gtcttttttt gcgagcccgc
   883801 cgagcatgct gtcaggcaca tttctcccgc catgccggaa atgtgccaaa atcttccgca
   883861 attggggcgg ttccctgcag ccgcgagacg ctcgacggcg gcgctcaaga aatgcccgga
   883921 ggattacctt tgaacaccag ccccaacgat cttgcgctga ttgcggtcat gcgccggtat
   883981 ttctcgctga aggaggaggc gagcgcattg aaggggcggc ttgaggatgc gcgcaaggcc
   884041 gccggcgacg agatcgaccc gttctatgat ccgcgtcgca atgcgcccca tgccgaggac
   884101 attctggtct ggcaccggct ccgaagggaa atggacgaac tgatgagcct cgctgcgacc
   884161 tggggacggg gcggcagcat cgacgcattt gcgccggcac cggcggccga gcccgcattt
   884221 ccacctgaga ccggagcgtc gatggaggag tcataggacc cggggcgggc gcccttgagt
   884281 ccttaaacag cccgctatgc agcaggccac gcagggaacg atggccaagg aggcaagttt
   884341 ggcgtacatc attgtatcag gaggaacaac tcctcattgc ggagctccgg agtgtagcgg
   884401 acccgatcag ggactgacag gggtcgtagg attgccactg cctggcaacc ggcggccgag
   884461 tgacggaaaa tgcgtttgaa acccgattgc gagatatcag ccggtgtctg agtttatggc
   884521 tacatccaac ggcaggaatg ccgacccagc ctctgccttg cgggattgcc gaacggcttt
   884581 catcggtgtt gccatcgcaa gcgcgctcgt caacgttcta tacctcaccg ggtcgttctt
   884641 catgctcgaa gtctacgatc gaattctgcc gagccgcagc attccgtccc tggttgctct
   884701 ctctcttctc gcgctgctgc tttatgcctt tcagggagcc tttgagctcg ttcgcgggcg
   884761 gatgctggtg cgcatcgccg gtgccctcga cgagagcctg aacggtcgca tttaccgcgc
   884821 catcgtgaag gcgccgctga agctcagaat gcagggggac ggtctccagg cgctgcgcga
   884881 tttcgatcag gttcggtcgt tcctgtcggg tgccggcccg gccgcgctct tcgacctgcc
   884941 ctggctgccc ttctacatcg cgatctgctt tcttttccac ccggtcatcg gtttggtcgc
   885001 gatcatcggc ggcctggtcc tgatgttgct cacctatctc accaaccgcg gcacccaggc
   885061 gcctgccagg aaagcctcgg aggccggagg gcttcgcaac gccttcgcgc aggcctccca
   885121 gcgcaatgcc gaggtggttc atgccatggg aatgtcagcg cggctgacgg cgatgtggga
   885181 gaggcgcaat acggagttcc gcgatgagaa ccgccgcacc tccgatatcg gcaatggcta
   885241 cggcgcgttg tcgaaggtct ttcgcatggc gctgcagtcc tgcgttctgg cggccggcgc
   885301 cgttctggtg atacgaggcg aagcttcgcc cgggatcatc attgcgggct cgatcctgac
   885361 agcccgggct cttgcgcccg tggaacttgc catcggcaac tggcgcggcc tcgtcgcagc
   885421 gcgccagagc tggcaacgcc tcaaggaatt gctcaaagcc ctgccggaag ccgatgcacc
   885481 actccagctt ccgaccccgc gcgatcgcct caccgtcgaa gggctggcaa gcggtccgcc
   885541 ggcggcgcag cgcctcatct tgtcggatgt gaatttcacg gtcggtgcgg gcggtgccgt
   885601 gggagtcata ggaccgagcg cttcgggaaa atcgtctctg gcgcgcgcga tcctcggtat
   885661 atggccggcc tatcgcggct cggttcggct ggacggtgca gccctcgatc aatgggacag
   885721 cgatgaactc gggaaacaca tcggctacct gccgcaggac gtggaactgt tcgccgggac
   885781 gatcgcgcag aacatctgcc gttttgccga agacgcgaca ccggacgcga tcgtcgccgc
   885841 cgcaaaggcg gcgcgcgtca acgatctgat cctccggctt ccgaacggct atgacaccga
   885901 gatcggcgat ggcggcatga cgctctcggc cggccagcgc caacgggtgg ctctcgcgag
   885961 ggccctttac ggcaatccct ttctcgtcgt tctcgacgag cccaattcca acctcgacgc
   886021 cgagggcgag caggcgctca gcgaagcgat catgagcgtg cgcagccgtg gcggcatcgt
   886081 catcgtggtc gcccaccggc cgagcgcact cgcaagcgtc gatctcgtgc tgatgatgaa
   886141 tgaaggacgc atgcaggctt tcgggcccaa ggagcaagtc ctcggtcagg tacttcgtcc
   886201 gcaacaggtg gagcgacaga attcgctgaa aatcgttgca gaagggcagg aggcgaagca
   886261 atgaggggat ggccccaggc gaaaccgact gcacatcggt cgctctcccg gcatctgatc
   886321 ggcgtctcgg ttcttgcgct cgccctcgtg gcgggcgtcg gcggctgggc cgcgacaacg
   886381 gaactgtcca gcgcgatcgt cgccggcggc gtcgtggtcg tcgacgataa tgtcaagaaa
   886441 gtgcagcatc tgaccggcgg catcgtcgga gagctcctgg tcaaggaggg cgatcgggtt
   886501 gaggccggcc aggtgctgat ccgcctcgac ggcacgacgg tacgcgccaa tctcgcgatc
   886561 atcgaaggca cgctggcaca attctatgcc cgccgtgccc ggctgctggc cgaacggatc
   886621 ggtgccgcat ccttcgagat agaagaagat ctcgccgagt tcatctccgg cacggcggcg
   886681 gagaagctca tcgacggcga acagaggctc ttcgcgaacc gtcgctcggc cctgttgggc
   886741 atgaagggtc agctcgattc gagaaaggcg cagcttgccg acgagaccga gggtctgacg
   886801 gtacagttga acgcgatcga ggacgcgctg aagctgatcg cggaggaact gaccggggtc
   886861 gactcgcttt tcggtcaggg gctcgtgccg atgcaacgcg ttacgacgct gaagcgccag
   886921 cgcgcggaac tcgagggtgg gcgtggccga catatcgcgg cccgcgccca ggcgcgcggc
   886981 aagtcgagcg agatcgacct gcagatcctg cagctcgatg aggaccggcg caccgaaatt
   887041 tccaaggaac tgaccgacgt cgaagccaag atcgcagaat atgaggaacg ccgcacggcg
   887101 gccgccgacc agttgcgccg cctcgacatc accgccccgc tttccgggcg catctaccag
   887161 ctggcaattc acacggtcaa tggcgtcatc aatccgggtg aaacgctgat gctcgtcgta
   887221 ccggaggtcg acgacctgac cgtcgaggcg aaggtagcga cccatgacat cgaccagatc
   887281 cgtgtcggcc aatcggttga aatccgcttc agtgccttca atcagcgcac cacccctgaa
   887341 gtggaggccg aagtggtgac ggtcgcgccg gatctcgtca ccgacgagcg caccggagcc
   887401 agctactatc ccctgcgcat tcgcccgaag acggagagcc tcgccaagct gaaggggctt
   887461 tcgctctatc cgggcatgcc ggcggaagtg ttcatcaaga tcgccgaccg tacggtgatc
   887521 tcctatttga ctaagccgct cacggatcag atgcggcatg ccttccggga agattgagtc
   887581 ggcaggtgcg atatcagaag cgtcggtgcg actgcgtcag cgagagcgga tagcgggtcg
   887641 gatgataggc cgcggcgctg atgtttacgg tacggttgtg gctgtcatag gcaatctgat
   887701 ccagcgtcag cacggcggcc ggccgatcga gctggaggag ggaggcctcg aggtcggatg
   887761 caagcctcgc gctcagcgtc gattgtccgc gtgacggaag gatgccgtag cgattctcga
   887821 actcatcgta aagcgacctg ttttcgaccg tccagtcgat gtcgaggatg ccaggagtca
   887881 gcgaggcgga gaaccaatcc ctctgcacga ccaccggcac cccatcgagg aggcggagtc
   887941 tttccagaaa cactacctct gccccggtcg gcagtgaaag cggtctcgca acttccgggt
   888001 cggcccgtgc gatctccgcc ctgagaagcc gcatgcccgg ctttcggttg ttggcatggg
   888061 ccgtctgggt gaagctgcga accacctcca gttcgtagac cggagcgggc tcggttacgt
   888121 agataccctt tccgggccgc gtttgcagat aaccgaggtt ttcgagttcc ttgatcgcct
   888181 ggcgcacggt gatgcggctg acgccgtaaa ctgccacgag ttcccgctcc gacgggagct
   888241 tgtcgtttac cgccaattcg cgacgctcga tcatgcctct cagaagattt cgcagttgcg
   888301 cgtaaagcgc atccggatga ttgcggtcga tcggcctttc gtccgggagg ttttcctgtc
   888361 gtgccatgct ctctggtttc agcgcgggtt tcgggatgat gaattgcatt gcacctgccc
   888421 gggccgaaga caagtggtga acagcgttcg ccagcatgcc gatgctccgg caacgggcat
   888481 ggcaaacgaa agaaaaccag cgccgccatg aattgacata actggctata tccagtagcg
   888541 ataccacgag cggaacggcg gagtaaagaa tgaaactgac cttgatcggc ggcggcggcg
   888601 tccgggcgcc cctttttgtc ggctcggccc tcaggcgcgc ggaaagaagc ggcctgaccg
   888661 agatctgtct gcaggacatc aatgaacgga aactcgaact cttcgggcgc ataagtcagg
   888721 aactggcgcg tcgcatgcag tctcccgtcc ggatcacaat ggccgccgac gccgagcgcg
   888781 cgctcgaagg ggcgagttac gtcgttacga cggttcgccc gggcgacgag gatgggcgca
   888841 tcaaggatga gcgcattgcg ttggcccatg gggtgctcgg ccaggaaacg accggccccg
   888901 gcggcttcgc catggcgcta cgcagcattc cggtcatcct gaaatatgcc gagatcctga
   888961 agaacgtcag tccggatgcg tggctgttca acttcaccaa tccggcggga ctcgtgaccc
   889021 aggcgctaca agacgaaggt tatcatcgca ccgtcggcat ttgtgacggg gcgaacgggg
   889081 cgcaggaagc gctggcgcgc tggtacaagg tgccgcagaa cgacgtgcac tgcgaggttt
   889141 atggcctgaa ccatctttcc tttacgcgac gcgcgacgat cgacggcagg gaagttcttc
   889201 agtcgctgct cgatgacgac ggattcattc gctccacatc gcagcgaatg ttcgatgcgg
   889261 gcctgatcag aagccagcgc aactggatca acgaatatct ctactattat tattatgcgg
   889321 agaaggcggt cgaggcgctc aaggctgatg cgcgcacgcg cggcgaggag gtcaaggacc
   889381 tgaacgcggc actgatcacc cggctcagcg ccatggatat ggatgccgat gccgaggcgg
   889441 ctcttgctgc ttactacgcc tacgagcggc ggcgcaacgc cacctacatg cattacgcgc
   889501 tggcagacgc ccccagcatg gaagaggccg acaggcttgt cgagggcctc gccgccgggg
   889561 agacgggtga ggagggagag ggctatgccg gtgtcgcgct caacctcgtc gatgcgctgc
   889621 agaccggaaa agcgtgctat agcggcctga acgtgcgcaa cgaaggtgcc atcgaaggct
   889681 tgcgggacga cgatgtcgtc gaggtgagct gcgtggtggg ccaggacggc attcggccga
   889741 tgaagatcgg tgccatgccg gaagcgcagg cgcagctcgt ccatagtgtg aagcgctacg
   889801 agcggctggc cgtgcgggcg atcaggcaac gcagccgcga tctcgccgta caggcgctca
   889861 tggctcatcc cctggtgctt tcctactcgc gcgcggtgcc tctcgtcgat gaatatctcg
   889921 cggcacatgc tgaattcgca ggggaatggt cgtgaacgac aacggcgtcc gttcccgcta
   889981 cgacgttatg gtggtcggag agtactactt cgacctgatc ttccgcgggc tcccggaagt
   890041 accgaagatc agcgccgatc tctgggcgga ggagttcgag tgggttcccg gtgccgccta
   890101 ttcgacggcg ctgggctttg cgcggctcgg aacgagcgcc ggttggtggt gtcaattcgg
   890161 caccgatatc ttcagccgca tgatcgtcga tcaagcccgc agcgagaata tagatgatcg
   890221 cctcttcatc catctcgaca ggccgctgcg ccgcgtcagt gcagcttttt ccttcgcgca
   890281 cgaccgcgga ttcatcagct acgccgaaga gcccgatccc ctgccgacgc ctgaggatct
   890341 ggcgcggatc aggccgcgca tattgcttct tcagggcttc tcgctcgacg atgaacggcg
   890401 gcggcttatc gaggcggcgc gcagcctcgg tatcaccgtc tgctccgact gtcagcatgt
   890461 cgactatcgg ctgtcgaccc ccggaatgga ggagatgctg gggctgatcg acgtctttct
   890521 gccgaacgca tcggaagcaa aggcgctgac gggcgaagac gacgtggagc gcgcgctttc
   890581 atcgatcgcc cgcttctgtc cgactgtcgt catcaagtgc ggagcggatg gagcgattgc
   890641 cgcctccaaa gggcggacga cccgaatgcc ggcgctcgcc gtcgccgtat tcgataccac
   890701 gggcgcaggc gacagtttca acgccggctt cgttcacggg ctattgaccg agcctgatat
   890761 cgagggcgcc atcgagctcg gtgtgatctg cggctcgctg gcagtgacgg gatacggcgg
   890821 ccgcaacctg cctttcaaag aggatctgac gcaatatcgg cggcgggagc cgcgatatag
   890881 cttgcgttca caagagaaca aatgagggaa cgaacatgaa gcatcttttg aaaacactgg
   890941 caggtatgac cgtcattgcc gtcgtatccg cctttcccgc aaaggcggat accgtttcga
   891001 tgttttgctc ggcgaccgac tacgagcttt gcgagaaggc tgtccagaaa tggacgaaag
   891061 aaaccggcca tgacgtgaaa ctcaaccgga tgccgcagaa cctcgacgac gccattccga
   891121 tctatcagca attgttcgcg gcccagtcga ccgacatgga tgtcctctac atcgacgtca
   891181 tctggctggg tatgttcaag gatcatctcc tcgacctgac gtctctcgta cctgaggagg
   891241 aggtgaaggc gcatttcgcc tctgccgcgg atgcggcgcg cctcgacggc aagctcctgt
   891301 cgatgccttt ctacatcgac accggcctga tgttctatcg taaggacctg ctggagaagt
   891361 acggcaagca gcctccgaag acctgggacg aactgacggc gaccgccaag gagattcagg
   891421 atgcggaacg caaggtcggc agtccggata tatggggcta tgcctggcag ggccggagct
   891481 atgagggcct gacctgcgat gcgctggagt ggatcgcttc ggccggcggc ggcacgatcc
   891541 tttccgacga cggagaggtg acaatcaaca atcccaagac ggaggcggct ttgagccgtg
   891601 cgcgcggctg gatcgggacg atttcgcctg agggggttct gaactacgat gaggaaaact
   891661 cgcgtgccct cttcgagagc ggcaatgccg tctttcaccg gaactggcct tatgtgtggg
   891721 gaacgtcgca ggccgaaggc ggcaagctcg tcggcaaggt cggggtgagc gcgcttccgg
   891781 tgggtgcgga aggccagaag tcgagcggtg cgctcggtac cgcctatctc ggcgtttcca
   891841 aatattccaa gaatccggag cttgcagcgg agctgctgcg ctacatggta ggtgcggaag
   891901 accagaagat gcgtgcaatc gaaggcggct acaatccgac cgtggaggcg ctctacgaag
   891961 acgccgatgt gctggcgaag attccgttcc tcggcatggc gaagaccgcg ttcgaagaat
   892021 cggtcgcgcg tccctcggca gccacgggca agaactataa tcgtgtttcc cgtaccttct
   892081 accgggcggt tcacgacatc atctccggca aggacgatgt cgcgaaggaa ctcgccgatc
   892141 tcgagcgacg cctcgaacgc gacgttaaag cgaaatgacg agagcggcgc cctcggccgg
   892201 tcgggggcgc cgcatcgaca cggtggcgcg ggccgcgctg ccgtgaaagg cctgaagaac
   892261 tggcgggaca atcggaaacc gtccccgtca gcaagtgcgc agtcgtaaag ccttggatgg
   892321 ttcgatgttc gaatggaaca gaaaaccgtt ctggaaggaa aatggaatgg cttcggtcac
   892381 cctgaggaat gtcagcaaga ccttcggtac ctatgacgtg atccggtcca tcgacctcga
   892441 gatcgaggac ggcgaattcg tcgtcttcgt cggtccgtcc ggttgcggga agtcgacgct
   892501 tttgcgattg attgccggtc tcgtcccggt ttccggcggc gacgtattta tcggtggcga
   892561 ccaggtgacg gatgtgcccg cttcgaagcg aggacttgcc ttcgtcttcc agtcctatgc
   892621 gctctacccc catatgaacg tcgcgcggaa catcggcttc gcgctcgaaa cggcgcggct
   892681 cggcaaagac gagatgcggc gccgtgtcgc gagggtcgcc gacatgctga agatcggcca
   892741 tctgctcgag cggcggccgc gccagctttc cggcggtcag cggcagcgcg tcgcgatcgg
   892801 tcgagcgctg gtcggccagc cggaggtttt cctcttcgat gagccgcttt ccaatctcga
   892861 cgcggacctg cgcatggaaa tgcgcttcga gatcgccaag ctgcatgccg acgtcaggac
   892921 gacgatgatc tatgtcaccc acgatcagac ggaagcgatg acgctcgccg accggatcgt
   892981 gatcctcaat cacgggaaga tcgagcaggt ggggcggcct cgcgcgctgt acgaccggcc
   893041 ggcaaatcgc ttcgttgccg ggttcctcgg cagtccgagg atgaatttcg cccctttgga
   893101 gacggccggt gcggccgttt cgatgctcag gggtgcaggt ggcttcacct atgcggccga
   893161 tctcgctgcg gcagaaggaa cgcccgtcga gctcggattg cggccggaaa gtctgcagct
   893221 cgtcggtgcg gatgtgaagg gcgccatacg cggaaccttc gagcggatgg aggatctcgg
   893281 ctacgaatat gtctgctatg tgcgtctcac cgaaacgctg gtctggacga tccgtgcgac
   893341 ggggagcccg ccgcaaatca cgcccggcga gcccgtcggc ctgacctggc agccggaaag
   893401 tctctacctc ttcggagagg atggcaggcg catcgaccac cgcacgagca ttccgctgtc
   893461 ccttggagcg tcgtcgtgaa cgccgcccgc cggatggagc gccagcagca ccgcaccgca
   893521 tggctcttcc tgcttccctt gctgctgacg ctggccgcgg tagcgatatg gccgctcggc
   893581 cgcagcattt tcttctcctt caccgacgcc tacctcgatg cgccctcgga ctacggattt
   893641 gtaggttttg acaacttcgt ggaggtagcc gacgatccgg tgttctgggg cgccgttacg
   893701 aacacattgg ttttcacgct cgtatccgtc gctctggaga cactccttgg gcttgccatc
   893761 gccttgctcc ttcaccgtgc ctttctcggc cgcggcatcg tcagggctgc gatcctcatc
   893821 ccctgggcga tgccgatggt cgtctcggcg cgcatttggg aatggatgct caacgaccag
   893881 ttcggcctga tcaacaagct tctcgtcgca ctgggactcg ttgaaaaggg tatcgcctgg
   893941 acagccgacc cgtccttcat tcttggaacg gtgatcttca tcgatgtctg ggtgacgacg
   894001 ccgttcatgg tgcttctcat tctggccggc ctgcaactga tccccgagga aatatacgag
   894061 gccgcggagg tttccggcgt gccccactgg aaacgcttct ggtccataac cctgccgctc
   894121 gccatgccgg cgatcggcgt tgccatcctt ttccgcacgc tcgacgcgct tcgcatgttc
   894181 gacttgagct atgtgctcgc ggcaaacaac gaaaacacca tgacgatgtc gatctatgcg
   894241 cgcgatcaac ttatcagttt tcaggacctc ggccttggag ccgctgcatc cacatgggtg
   894301 ttcatgatca tcgggatgat cgctatcgtt atcgtcggcc ttttgcgcct cgatcgggcg
   894361 gcgggttgag aagatggcaa tgacggcgag cactgctggg agacgctatt ccaacgcaac
   894421 ctatcgggcc atgcgccgct taaagacggt cgggctctat gccggcgttg cggccgtcct
   894481 cgcctacatg ctctttccgt attattgggc gatcgtctcc tcgacaaaga cggggcaggc
   894541 gctttaccag ttcactctgc tgccggcgct ggatttcagc aactactggc aattgttcaa
   894601 caaccccgta ttcatgggcg cgctcgtaaa ttccggcgtg gtcgccctgg tcagtacggc
   894661 gatttctctc gtcataggca ttcttggcgc ctatgcgctc gggcgcctgc atttcccgcc
   894721 cggccgtatg gttctgatcg ccgtactcat gatctcggtc ttcccgcaag tggtggtgct
   894781 ttcgggaatg tttgaagtga tcggatggct cggcctctat aaccgcccgt cggggctgat
   894841 cgtctcctat ctcatcctca cactgccgtt tacgacatgg atcctcacga gcttcatccg
   894901 tgatctgccg aaagagctcg aggaggcggc actcgtcgat ggctgttcac gcctgcgtat
   894961 cctcacgcac gtattgctgc ctctgatggg gccggcgatt gccagtaccg gtctgctgtc
   895021 gttcatcctt gcgtggaacg aatttctctt cgctctcacc ttcatactga cggacgagaa
   895081 caggacggtt cccgtcgcga tcggcctcct gacaggaagc agccgctatg aatatccgtt
   895141 cgggcagatc atggccgctt ccgtaacggt cacgctgccg ctgctcgcac tcgtgctggt
   895201 cttccagcgc aagattgtgg ccgggttgac gtccggcgcc gtgaaggggt gacaccgacc
   895261 gccgccgcgc ggaactctat gtgccaaaat tggcatcatc tattttcgtg attggacttc
   895321 gggatcagtt ggagtcacgc ttaatcggct gcagcgcggc gcgtcgttgg acgcgcagag
   895381 gtcggtgcag cgcttcgatt tgttgcgtgt ccctgaacct gatcggcagg cgggtgcgcg
   895441 gcaagtggaa ctgggggacc aactatcgtt agagtaggag gtcgcaatga agcaccaagc
   895501 aatcgagcag ttacagggcg tcgccgaggt caagcaggac tttccgcgac ggacattatc
   895561 gcgcaaggag cgccttgagc gttgggcgga gctccttgag cgtgaccctc acagacgcct
   895621 ctcgacactg cacgagacag agtatcagcc agcgagagtc cgcgcggcca tgcgcggtga
   895681 tggttcgccg atctccgttg ccttcgagga cccggtcttc cgggccgccg gaatggagaa
   895741 tgacagctac ggtgaagcca ggcgtttctt cgagctgagc gacgagcaat tgcataaggt
   895801 catctgctac tgccatttcg gtgcaaccgt cagcgcatcg acggcctcgc gccacatccg
   895861 cgcaatgctt atcgagaaac agccaggtct gttcgctcgg ttgcgccaga tgttcgccgg
   895921 ctgaagcacg cgacctggtc agagggccgt tatcgagcgg ccgccggacg aggcgggccg
   895981 cagtgcgtgc gcttgaaacg tgcacgctct gcggtgctcc catcgccttg gctggcggct
   896041 gcctccgaag cggtgtatgt tccgtcacca tcaggcccgc acggtctttt ggccgaaatt
   896101 tcatgcattt tctcgaaccg cgtcgttcaa ggataagcat taggaaacaa gggctcgagc
   896161 ggtcgaggag ctggcggaaa cactatggct caaagggcag gtaatgcgga tctcccgctg
   896221 catggcggcc gggtgccgcg gtggctcggc gatcgcatga cgcgcttggg cgcgctggtc
   896281 accgaagcga tcgtacatca ctatggacgc gacgagtttt tgaggcgcct ggcgcatccg
   896341 ttctggttcc agtccttcgg tgccgtaatg ggaatggact ggcattcgtc cgggatcacc
   896401 acgagcgtca tcggggcgct gaaacgcggc ctcacgcccc ttgccggcga gctcggcatc
   896461 catgtttgcg gcggccgcgg ccagcactcc cgcaagacgc ccggcgaact cgtctcgatc
   896521 ggcgatcgca tcggtttcga cggcggcgca atggcggagg cgagccgact cgtagcaaaa
   896581 gtggacagtg ccgccgttca ggacggcttc gacctctacc tgcatggctt catcatcacg
   896641 gacgatgcca aatgggtggt cgtccaacag ggcatgaacg gcgaccggcg ccaggcgagg
   896701 cgctatcact ggctttccga agggttgacg agcttcgtcg atgcgccgca cagcgcgata
   896761 gagggcagag gacagggcga aatcttcaat ctcgcagacc gccgggctgc cgcgtcgcgg
   896821 agtgcgcagc tcgatctcct ccactcactc gggcccgacg gactcttgcg tgaggtcgcc
   896881 tcgatcgagg ctcgcgctgc tcctcaggca gagccggcac agccgctgct gccgcatctc
   896941 ttcatgcccg cccatcacga ggttcgtgaa tccgacgtca atctccggcg ccttcacggc
   897001 agcttcgccg cggccgccga gcgcggacct gaagacttca aggacctgct cctcgtgccg
   897061 ggggtcgggg cccggacggt caaagcactg gcgatggtcg cggaggtcgt tcacggaacg
   897121 ccgtgcaggt tctccgatcc cgcccgcttt tcgctcgccc atggcggcaa ggaccgtcat
   897181 ccgtttccgg ttccgttgaa agtttatgac gagactatcg gcgtcatgaa gtccgcggtg
   897241 agtaaggccc ggctcgggcg cgaggaggag cttgcggcgc tgaagcgact tgacgagcag
   897301 tcgcgacggc tggaacgcta cgtcaccggc cctgacctca aggagatcgt cgcgggcgaa
   897361 ttcagggact ccgcgcgttt cggcgggcgc agcatcttcg gctgggaacc gcccgaggaa
   897421 gaaacgatca tttccgagcc gggcgaccgc gcgcggcgtt gaagcgggaa caatcggcgc
   897481 agcgatcgat ttaagcagca tgagcgggat tgcgcggacg cggttttacg ccggtatccc
   897541 gctccctgtt cagccgaccg ttcatggagt tttcgatgac cgctgcgatg accacaacca
   897601 atcacgatac aatccgcaaa tggatagaag cccgcgaggg acagccggcg cgcgttaaga
   897661 atgcaaacga gggcggcggt ggccttcttc gcgttgattt cggcaaaccc gaagatacgc
   897721 tggagaaaat ttcctgggat gagttcttca agattttcga tgaggagaaa cttgcgtttc
   897781 tgcaccagga tatgaccgaa gacggacaga cgagccgctt ctgtaaattc gtcaaccgag
   897841 actgaccccg gaaggacatc ggaaagagac ggaaagagca ttttgaggcg acccacgtgg
   897901 gaaaggatct cgtgatgctt gccaccagaa agccggagcc cgccgcagaa cgcgaggagc
   897961 gccccgttcg acccgcagtg gacgacgagc cggcacccgc ggcgatcagg agggccgcga
   898021 cggacgctcg cgaaagcctt catgagccga acgccctttt ctggcgcggc atctggatga
   898081 ccctgtttta gagcctttcc tgtccggcgt cccctacgtt gcgctctatc tctccgagcc
   898141 gcgccgtcag gcgtttgatc tcgtcgcgct tctcggcaac aacatctctc gccgcctcga
   898201 gcctgtcgcc tcccggcacc gtgccgatgg ccgtgtgtgt ctcggtcgcg atggtgtcga
   898261 tttcggcctg cagccgggcg atccgctcgc gcagcccgtc gagttccctg ccgatatcag
   898321 gtgcgcccat ccgatctctt tcccatgcat cgatcggttc gtcgacgctc ggcggatcca
   898381 gcggacgagc gtcacccccc gggcgcggtt ctccaggctt gtttgtgctc atgactgatc
   898441 tcctgtaagc gtcatcaacg ccgaactgcc gcctatgttc cctcgacgcc cttttcgatg
   898501 caacattcga tcgggccctt ggaacttccc aatgccgtcg ccgttttccc ttcgccacct
   898561 gggagggacc ccatgcattc agaggaatat ctagagcttc actatgatct gttgagccac
   898621 cgggcacttt tgtcatgcgg ccgcaacgct tatgtgttgc cggacatcta tgagaccaag
   898681 gaaatggcgc aggtcgccgc ccagaagttc gcctgggaga cgctcggcct gaaagagcgg
   898741 gcggccgggt gccgcactgc cgccgacctg ccggtctggc tgcgctgaaa attgcgccga
   898801 ttgcgatccg gagaccttgt cacccgtcag ctccgtgcat gcattgcgga gtgccagacg
   898861 atgacggctg gtccctctgc gccgagaacc gggtcgaagc gaggcaacgg caccgcgtcg
   898921 atcgcgatac ggtcatccgc cgtcgcggcg ccgcttttga tatcggcgtg ttgctccggc
   898981 ggataaccgc cgataacgag gaagtcggcg ctcgcctcgt cgcggcggtg gccggttccc
   899041 gcgggaagga gaatgacgtc gccggctgcg acctcgactt cccggccacc cggcccgccg
   899101 atgaggaggc gcgcccggcc ttcagcaatc ccgagaacct cgtgagcacc gcaatggtag
   899161 tggtgatggg caaagacccc gttgcgccag agaccgagcc aaccattggc ccggaagcgt
   899221 tgttcgatcc gtgtggctgc attttcggta acgtcgatcg cctggcggta gaccagcacg
   899281 ggcaagcgcg gattgttcgg tacgccgccg ctttcggcga atatgaactc ttcgaccttc
   899341 atcaatttct cctgcgcaga gggtcttctg tttctccgga acgtttttcg cggctgcatg
   899401 tttcgttaaa tcgtacccgt tcaaaaagca ggctggtgca ttgcagcggc gaactcggga
   899461 agtcggcgga atccgcgtat gagggatctt ccatgtcata caaactctat tactgggacg
   899521 gtattccagg ccgcggtgaa ttcgtgcgcc ttgcgctgga agagggagga gcggattacg
   899581 tcgatgctgc ccgcgagccg gggggcacgg atgaaatgct gaagctgatg aaggcgcctg
   899641 gcggggccgc tcctcccttt gctccgccgt tcctcgtcga tggcgatctg cttatcgccc
   899701 acgtcgccaa cattctattc tatctcgggc cgaggctcgg ccttgcaccc gagggcgaag
   899761 ggcttcgcac cattgctaac ggtctgcagc tgacgatcac cgattttgtt gcggaaatcc
   899821 acgacaccca ccacccaatc ggcgtatcgc actattacga gagccagaag cccgaagcgc
   899881 tgcggcgcgc ggccgatttc ctatccgagc gcctgccgaa attcctcggc tatttcgaac
   899941 gagtcctttc gcagaattcg agcgggccga accagatggt cggcgaccgg ctgagctacg
   900001 tcgatctttc gctcttccag gtgatcgagg gacttcgcta tgcctttcca agggcgatgg
   900061 acgcctatga ggcgaacatt ccccgcttgg ttgacgtgca tgatgccgtg cgggtccggc
   900121 cgcgaattta cagctatctc gcctcggagc ggcggctggc cttcaacgag tcctgtatct
   900181 tccgccacta tcccgaactc gacaggcagt cctgaccgtc aaccaattcg aaccgctact
   900241 ttggcgagat cgtcgacgaa acgggcgcgt tccgcctcgg ggtcgcctct gccgcggatt
   900301 ctcagcagat aggagggatg aatcgtgacg agcacggaga acccgccggg tgctggcaca
   900361 aactgtcctc ggttttttgt gacgccgacg cctcgaccga gcagcgacat cagcgccgtg
   900421 gccccgagcg caacgacgat ttcggggcgg agctcatcga tttcggcgcc gagccaccag
   900481 gcacaggcct ggacctcgcc ggcatttggc cgcgaatgca gccggcgctt gccgcgcggt
   900541 tcgaacttga agtgtttgac ggcattggtc agatagcatt ccgacctatc gatgccggct
   900601 tcgtgcatgc actcgtccag aagccgcccg gcgggcccga cgaacgggcg ccccgcgaga
   900661 tcctcccggt cgccgggctg ttccccgaca agcacaacgc gggcgtcggt cgggccttcg
   900721 ccgaagacca gctgcgtggc attcttgtag aggtcacacc gctcgcagcc ctcggcctcc
   900781 cgccgtaagg aggcaatcgt cggtgcctct gcatgttcgc ccgcgagcgc tgggccaagt
   900841 ttggcggatt ctcttggcat atccgtggag gatctcctcg tgttccttgt tattgctgcg
   900901 gccgatcttc gggcctaacg gtgatgcaag aggcatgctc cctcgcgatc tcatcgtgca
   900961 atggcgacca cgatgccgag gccggccagt tcggtgacgt cgggcgtcct ctcgccggcc
   901021 gcttcgctgg cgaagatcgg ctgaccccgg aacgggggca tggcgtgcgt ctcctgtgaa
   901081 agattgacgc gcatttccag gcaggactcc ccgaactgcc agtcgacggc gatgacaccg
   901141 tcctctgtct cgaatgcccg gtgttccggc attgcggtac cggccatcat cggcacgata
   901201 tgcctctgcc ggatcgaagc aaggtcgcgc atataggcaa gacgccgctc gccggccgga
   901261 cttgccgcgc ggctccagcg cagcttcgag ccggaaaaaa cctccggatc cagcgggtcg
   901321 ggcagatcct ccacggtctt gccatttgga agcccgccga aattctcggc ttcgtcccgg
   901381 cgtcccagcc ggatcgcgtc ggcgatttct ccctgatagt cggagaagaa gtagaagggc
   901441 tgtgtctcgc cgtattcctc acccatgaac agaaggggaa tttgcggcgc gagcatgtgc
   901501 atggccgtca acacccgcag gctatcctct cgaaccagcg aggcaaggcg ctcgccgaaa
   901561 gcgcggttgc cgatttggtc gtggttctgc aggaaattca cacggccctg cggcggcacc
   901621 cgggcgcggc ttccttcagc ggagaagttg tcctcctttg cgggcacggc gaaaccttcg
   901681 gccagcgcgc tgcggatctt gctccacggg gcctccgcga aggggcgata gtggcccctg
   901741 gtttcgccgg tcgctacgac atggagcgcg ttgtgaaggt cgtcgttcca tgccgcgtcg
   901801 aagagcatgg gcgtgccgtt ggcgtcacgc tcgagcaggc ttctgcggcg attggcgtcc
   901861 tccaccacca ggtggatttg gcggtcggcg aagcatttgc gcacttcgtg ctccagcgcg
   901921 acgaggaaat gcggattgct cgtgtcacga atctgttcag tcgcatcgag gcgcaaaccg
   901981 tcgaaacgga aatcgccgag ccagtaaagc gcattctcga taaaatatcg ccggactgct
   902041 tcttcctcga aggcaatgga cgcaccccag ggtgtggggc gatccttgtt gaagaagcgg
   902101 cttgcgtaca gggaaaggta attctgctcg ggcccaaaat ggttgtaaac cacgtcgagc
   902161 aggaccatga ggccgagcga atgcgctgca tccacgagcc ccttcaggtc atccggcgtc
   902221 ccataggcat tatgcggggc ataatgcagc acaccatcgt agccccagcc ccgcgcgccg
   902281 gggaactgtg cgacgggcat gatttcaatc gcggtaattc cggccgatgc cagatgcggc
   902341 aggcggttga tcgcggcgcg gaatgtgccc tccggcgtga agcagccgat atgcagctcc
   902401 gagatgaccg cctcctccca gggcctgcca cgccaggagg cggcccgcca ttcataggcc
   902461 gcctggtcga cgacgagcga cgcaccttcc gcaccccgct cctgtgccga cgaagccgga
   902521 tccgcaacct cggttccgtc ggccaatcgg aagcaataac ggtctcccgg cttcgtctcg
   902581 accgtgattt cgaaccagcc gccatcgctc tgccgcatct cgtgcggggt cccgtcgagg
   902641 acgagatcga caccccgctc gtcgggagcc cacagccgaa accggcaagt gtcttcgccg
   902701 acgaaattgg gcccccaagt ttttctgaaa cacggaggcg ttgagctttc tcgcatcgga
   902761 tatgtccctt gagatgaaag gcaaggaacc ggccgggggc gggaaagttc ccccgacggc
   902821 ccaccgggaa agaaggaaca aatacctgcc tgctgcgttg catcaaagct gctgggcaag
   902881 gcggtagagg gcgcgactga atgaatctgg cttttaccga actcgatttc ataaagcccg
   902941 aactcggtgc agattacacc gggcagggga cgcatttcgc cgtcttctcg gcgcatgcgg
   903001 agaagatcga gctttgtctg ttttccgaag acgggcgcga ggaaacggcg cgcatgccgc
   903061 tgccgaagcg cgagggcgac gtctggtccg gttacataga gggtatcggt cccggcgccc
   903121 tctacggtta ccgcgcacac gggccgtatg atccacataa gggccatcgc ttcaatccca
   903181 acaagctgtt gctcgacccc tatgccaaac aggttgcggg ggaactcatc tgggacgacg
   903241 cgcttttcgg atacacgatc ggtagccctg acggcgatct ttcattcgac gaacgcgaca
   903301 gcgctccctt tatggtgaag ggcgtcgttc aggacccggc cttcgattgg gcaggcgagg
   903361 aagcgatccg ccgcccctgg acggaaacgg tcatctatga agcgcatgtc cgcggcatga
   903421 ccatgacgca ccccgccgta cccgacgagc tgcgcggcac attcctcggc atggcaagcg
   903481 atccgatcat cgagcacctg gtgaagctcg gcgtttccgc catcgaattg atgccggtcc
   903541 agtatttcct cgacgaccgt tatctgatcg agcgcaatct cagaaactac tggggctatc
   903601 agacgctcgg cttcttcgct ccccacaagc gttatctgag gggcgaccgc atcacggaat
   903661 tcaagacgat ggtgaagcgg tttcatgccg ttggcatcga agtcctgatg gatgtcgtct
   903721 acaaccatac ggccgagggc tcggaacgag gcccgacatt gagcttccgt gggttggaca
   903781 atttcagcta ctaccgccag tcgcccgaca aaccgcgtca tacctacgac acgaccggaa
   903841 ccggcaacac cctcaacgtt gcccatccgc tggtgctgcg gatggtcctc gacagcctgc
   903901 gttactgggt gggagtgatg catatcgacg gctttcgctt cgaccttgca agcacgctcg
   903961 gccgcgaata catggagttc gatcgcgagg gcggtttctt cgacgcgatc cgacaggacc
   904021 cgatccttgc gggcgtgaag ctcatcgccg aaccgtggga cgtgggccag ggcggttacc
   904081 agcttggtgg tttcccgccg ccgtttcgcg agtggaacga ccagttccgc gacgacgtcc
   904141 ggcggttctg gaggggagac gccggcatgg ttccggtgct tgcggagcgc ctcgtcggtt
   904201 cgccggtaca gttcaggcat tcggatcgtg ccgcaacgtc gtccatcaat ctggtgagcg
   904261 cccatgatgg cttcacactg atggacacgg tctcctatgg tgaaaagcac aatgaggcga
   904321 acggtgagga gaaccgtgac ggccattcgg acaatcattc cgacaatatg ggcgctgaag
   904381 gtccaactga taacgcagag gttaacgagg cacgcaggcg gcggcgcgcc gccatggtcg
   904441 ctacgctgat ggtcagccag ggcgtgccga tggtgctcgg cggcgacgag ttgggcaaca
   904501 gtcagagagg caacaacaat gcctattgcc aggataacga gatcggatgg ctcgactggc
   904561 ccggcgcgga cgagggcttt ctggacttct gccgcaagct catcgccttt cgaaaacagt
   904621 ctcctgtcct gcgccaggag cggtttctcg acggggagcc tgacgagaat ggacgcgtcg
   904681 agatcgcctg gtacaaggcc gacggcaccc ccatggacga agatgcctgg cacactggcg
   904741 aactccgcct gatctgcgcc tatatctgca ggaccggcca ggatgaagcg tcgccggtcg
   904801 gcgagatcgt cgtcgtgctc aatgctggcg aggggtgcga gatagtcctt ccgcacgcga
   904861 atggaacgaa acactggctg cgggtgctcg acacggcagc cgaagagccg ttcgacatgc
   904921 gcgcgagtgc cgacagggag agcattccgg cacaaagcct cgtcgcctac gttccgcagg
   904981 agggctgaaa tggctagagc aatgtcggtc gacgtgctgg aatgtcgacc tgccgggctc
   905041 gccgatctcc cgcagcggct cgcggcgatc gggtctgtgc ccgaggaaac tgggctcgtc
   905101 tacgtcagcg acagcgagcc gggtattcgg cgccaaagac gtggcaaagg gttcgcgtat
   905161 cgcatgccgg acggatcgat cgttaccgat ccgtctgtta aaagccgcat agcggcactg
   905221 ggattaccgc ctgcctatga gaacgtctgg atctgccttg acgaacgagg ccacctgcag
   905281 gccaccggct atgatgcgcg cggccgaaag cagtatcgtt atcacagcga atggcaggcc
   905341 ctcaggagcg ccgacaaatt tgcgcaactg acggaattcg gcaaagcttt gcctaagata
   905401 cgccgcacca tacggcgcca catgcagggc ggcgtggaaa acatgcagac cgtgcttgcg
   905461 gcgctcgtgg ccctgctgga cgaagcgcat ctgcgcaccg gcaaccaggc ttatgtgcag
   905521 gccaacggaa gttatggcgc aaccactttg ctgaagcggc atctcagact tggcgacggc
   905581 tttatagaat tgaaattcac cggaaagggt ggcaagcgcg ttcagcgggt gctccgtcgc
   905641 ccgaagttgc agcgactgct cgaagaaata gccgatctcc cgggcaggca gcttttcgtc
   905701 tggaaggatg aaaacgacgc gcttcgaccg gtcgattccg gccggctcaa ccggtatctc
   905761 acggacatgg ccggcacagc gatctcggca aagacattcc gaacatgggg cggcactctc
   905821 gccgctttca cggtcgcgcg gacctcgatc gagcggggtg agtggccgac gatcaaacag
   905881 atgagcgagg cggctgcatc cgtgcttcac aacacgcccg caatcagccg gagcagttac
   905941 attcatccgg atgtgctcgc ccttgccgac aagtcggccc cggtctccgc gcggcagctt
   906001 caggcgcgtg ggcgttcagg aagtgaattg cgtgtggagg aacagcgttt gctaggcttt
   906061 cttcagcgca gcgcggggac gaaaaagcgc ctgcccttgc cccagtgaca gagtcacggc
   906121 cggagagcga tgtactctaa cgtcctgcgc tccccataag agcgggatgc gcgccgttca
   906181 aggcatcgca tccacgctta gtcagaattt agcacagctg gccgctcgga gcgttttcaa
   906241 ctgagatcgg tcaggttggg gttctgctgc acggtgctcg tatccggttc tatgcgcaag
   906301 ttgttttgca cattggtgac ccccgacacg ttttcggcgc agtcctcggc gcggcgtttc
   906361 gcccatttcg aactcaccgt gccgttgagt tgtacttcgc catttgtcac gctcacctcg
   906421 atgttcgagg catcgagagc gccgtcgtcg ctcagacgat cgctgacgtc ttcctggatg
   906481 cggccgtcag tccgcctgta gcctttgggg cccttgccac gatgccggtc catctcgcgc
   906541 cggcgttcgg catcttcgtc gccgaaccat gaggccacct catcgctcgc gcggtctagg
   906601 aaatcgcggt cgccacggcg gtaatcgcgc gtctcgccat agcctccata accgcggtag
   906661 cgcccttcgc cacggtagcc gtagccgggg ccgtgatagt ctctgaaata ccgctcgcgg
   906721 ccccgtcgat cgtcgtcgtc atcgctccag cgttcgcttt cactgcgata gcttccggtg
   906781 ggccatgaca tcgagttctc gtagtctgcg ccgcgaggct cgacttcctc accgaggcgg
   906841 ccgcgtcccc ggccgcgatt gcgctcggat ccatggtaag gatcgcgtga acgttcattc
   906901 tcccagtcgc ggcggggcca atcgcgtcgg gtgtagggat cgtatctgcc atagtccggt
   906961 tgtctgggca tgggctctct cctggctttt gctgatgtgg gccaaacctg cgatcggccc
   907021 aaagggttcc ccactgcgga cttgtcccgg ccagtcagcg gaacaatcgc ggtcggtcgg
   907081 gattgtccga tcgaggggtc ccgcccccgc atgtcatggg agacgaaaat gccgaacccg
   907141 aatcagccgg acccagcccc ggagccgccg ccgaagcagg cgccggattt gccgccatgg
   907201 tttcccgacg tgccgatcga ggagcccgag ccggacgtcc ttccggatga agttccggtg
   907261 cctaatccag acgaaaatcc ggagccgcca cggcatctgt gagggtgtgt ccgacataaa
   907321 gaccgggcgg aacaaatagt cgtccgcgcc gtttgaacct cgccatcagt ggagtccagc
   907381 ggcgaggtaa gggacatgga caatatggat aatgtggaca atgtgggcaa tcaaagggaa
   907441 gagctcatca ggcgccgggc ctacgtgatc tgggagcagg aaggccggcc ggacgggcag
   907501 cacgaacgtc actgggagca ggctgcccgg gaaatgcaag gatcagagcc gcaaggctcg
   907561 gaagagaagg gaaaagctgc gtccggtagc gggatacgaa ccaacgggag caggcggcgc
   907621 gaaaagcaaa ccgtgaccga aaccgaggct cccgcttcgc ccgctgaagg aagcgcggct
   907681 tctcgcctgg acggcgagcg ctgagcgccg gcccggcagc gataccggtg aggacctctc
   907741 caccaaagtg aaggagaaga caatgcgtgt atcagagatc atgacccggg acgtacatct
   907801 cgcaagcccc aatgatacca tcgccgctat tgcacgggag atggcggaaa acgacatcgg
   907861 cttcatgccc gtcggggaca atgaccgcct gatcggcatg ataacggaca gagacatcgt
   907921 cgtgcgcggc gttgcagatg gggtggaccc tcaggcaagg gtcgccgaca tcatgaccac
   907981 ggacgtgaag tattgcttcg atgacgatga cgtggacgat gtggcaagga acatgggcga
   908041 catccaggtt cggcggctgc ctgtcgtgaa ccatgacaag caactcgtcg gtgtggtttc
   908101 tcttgccgac gcagcgcgtg aacagccaca gatggcaggc accggcctaa aaggtgtgac
   908161 ggagcccggt ggatcccaca atcagaccca tcggaacggc tgacggccga tcaacttcgg
   908221 cgagagaagg gcagttcgaa agaggggcgc agtggcgccc ctttctggtt cggaacaagg
   908281 gaggaaatac catggtggtc aaccagaaaa gcctaccgga ccgcgccggc ccgatccccg
   908341 gcgatgcgga gcccgatgaa catgttgccg atgccggtga cgctggagga gttacgcggt
   908401 atcttgacca gccggagcac ccggacccgc cacagccaaa accgcgcaat ttcagcgcat
   908461 tcagtgaacg gcccgcgccg aggcccgcgt ccgagccggc ggaggaagcc gtcgcagcga
   908521 acgatgccac cggtggcgaa tattggaacc gggtactcgg cgacaatacc aacgccggca
   908581 cgcttcggtt ccttgccgcc gtggggctgt tcgttttgat cgctgccgcg ctgttctggc
   908641 ttgccggatg acggtcggcg aagattcagg tctgatcgag caaatcctaa atgtgatcga
   908701 cagttaggga ggggtgcggg ctgcctctag acaaaaacaa ttccgggaaa agcgtcacac
   908761 gcttttcccg gaatgccatg agttccgggg gttggctact gttgctgcgg ctgctgcggc
   908821 gcggacgtct gaagcttttc ctgaaccttc tgcgcaagtg ccgggtcgct ttgggccgct
   908881 ttcaggatcg tcgtatattc ctccaccgac atgttcggcg aggtttcaac ggccttgacc
   908941 atttcctggc tggcttcgtt ctggagcttt gtcttcgctg cctcgtcagt agtagcgcca
   909001 attttcgtgg aatattcctg ccttaccttg tcgacctgaa gataggcgac ggcgaaggcc
   909061 tcgatcttct gttcgctgat tggtgcgctc gtgccgccgg cgtcgggcag cgcctgtggc
   909121 tgcgtctgag cgggcgcttg ttgcgcctgc gcgagttcga gtgccgaagc ggggttgaga
   909181 agcattaagc tggaggctgc aacggtcagc gatgcaacga gtgtgtagcg ggtaatcatg
   909241 ttctgtcctc catgacgtgc atgacttgat cggcagcaaa accgcctttg ctcattcgcc
   909301 gcgccgtaga gaacgacgca gcgactcggg gaacatggac ccgtcgaaag ggctctgtgc
   909361 ggcgatgagg gggcaatttg ctgaccatta ggcggcagct ttgtggctcg cagcgagtgt
   909421 ggcggcgagg cattgtacaa ctgaaaaggg cgctcgaccc tttcggggag cgccctttga
   909481 cccggagaac gcaatcgtca gcggactggc atccgcgcgt ctggctctcg ataacgggta
   909541 gtggcgaaga aatggaaaca gcagcagcca atttcaagag ggcgcgagaa tatttgacga
   909601 acggcgtcga gcagacgctg cgtccacggc acatgcagtg accgtcacgc tgctggtttg
   909661 ctcgcgtgga tcgcaaaacg gtgctggctt ctccgcgcaa ggcccttgaa cagattccag
   909721 ttcttcgcct gcatcctgtg tatttctccg agatcggtgt ccacccttat gtcggtgaag
   909781 ccggatgcat gcagcagatc gacaacggct tcggcgcgcg cgccttgcga gaagtggacg
   909841 cgagccagaa tgctgcggtg cgtttccagc atctcacggg gctgggacgg cgcgtcgggt
   909901 ctgagaagcc cgacacgctg gccccaggcg ttgagcgagg aaaagaaccg ttcgagccgg
   909961 gtcgcattga cgaaatcgcc atcgacgatc agcaggcttc cgcctggctt gagcacacgc
   910021 agccattccc tgaaggccgc ggacgggtcc accagagtcc atacgagatg ccggttgacg
   910081 acgacatggt agtgatcgtc cggctccatt gtattttccg cgtctcccat gcggaaggaa
   910141 atattgcgcc ccctggtctt tgccttctgc cgtgcgcggt cgagcatcgg ttcagcccag
   910201 tcgatgccgg tcacccggaa gccgagatcg tcgaggaggt gcgagaccac ccctgtcccg
   910261 ctcgcaaggt cgagcgccgc gcggccggct ccttcgccga gatgccgcag gatgagccga
   910321 tgccaggcag cgcgttcctc ttccgaaaaa atctcatggc cgggagaaag gtcgaaagtg
   910381 gccgcgcgtt ccgaccagta ggctttaatt tcgtcgcgaa gatcataatt cgcccgcgtt
   910441 gccacgtcgc tcattttggg tcccggtttg tcctgtttgg aagcgttcta aaagatatat
   910501 gttgaccggt aaagtcatga aatattagaa ggcaccgaat ttcgaaggag cagggaacga
   910561 tgaagcttat caatatgctg gccgctgccg ctgcgggttt ctgcgtgctg atttcaagtg
   910621 cagccttcgc cgacacgatc aaggtgacgg atgtggccgg ccgcgaggtc gaagtcgatg
   910681 tgcccgtcaa gcatgtgatt ctcggagagg gccgccagat ctatttcgtc ggggcgctcg
   910741 acaaggacga accgttcaag cgcgtcgtcg gctggcgcga cgatcttgcc aaggcggacc
   910801 cggaaagcta cgcggcctat ctcgccaaat atcctgacat cgccaagctg ccgactttcg
   910861 gaggcatgaa ggaaggaacc ttcgacatcg aacaggcagt ggcgctgaag cctgacgtca
   910921 tgcttctgaa catcgacgcc aaaacggcga cggaggaggc tggctatatc gagaagctcg
   910981 aaaaggttgg tatcccgctc gtctatgtag atttccgtga aaagccgatg gagaataccg
   911041 aaccgagcat gcggatcatc ggcaagctct tcggcaagga agaaaaggcc gaggaattca
   911101 ttcaattccg cgccgatagt atcgtcaagg tgaccgttac cctcgccaaa gccgatccga
   911161 agaagccgct cgtcttcgtc gaacgggccg gcggctattc cgaagattgc tgcatgtcct
   911221 tcggcaacga gaatttcggc aggatggtcg agtttgccgg tggggtgaac atggcgaagg
   911281 acatcattcc cggcaccttc ggcaccgtca acccggagca ggtcatcgct tccaaccccg
   911341 accagatcat catcacgggc ggcaattggg aaggttatgt acccggcggc gcctgggtcg
   911401 gcgtcggcta tggcgccgac gagaaagagg cccagctcaa gcttgaagct ctcaccaaac
   911461 gtccggcttt tacgggtgtg aaggcggtca aggacggcaa cgtgcacgct atctggcacc
   911521 agttctacaa caacccctat cagttcgtgg ccattcagca gatggccaag tggctgcacc
   911581 cggacctctt caaggacctc gatcccgagg cgacgtttaa ggaattgcac gagcgtttcc
   911641 tgccattgcc ctataagagc ggctacttcg tctccctgaa cgtcagccag taagacacaa
   911701 ggatcggagg gctgagccct ccgatttcct gttcgcgagg ttcgaatgcg gatgctgaga
   911761 gaagtcttat cgatcgtcca ccggcccgat cctttcctct cgctttcaga aggcgcagca
   911821 agatgaccgc cattgccgag gaaatcgcag gcatcgaagg gcgcggtcgc taccgcgctc
   911881 tcgtcgttcg ccggctcgtc atgctgtccg gtctgcttgc agcgcttttc gtctccgtgg
   911941 ccgtcgacat ggcgctcggc ccggcgaact acccgctttc agacgtcctg accgcgctgt
   912001 tttgggccga gactgtgggc gaccagctcc gcgtggtgat ctgggacata cgcatgccga
   912061 ttgcactgat ggcggtgacg gtcggcgcct cgctgtcact tgccggcgcg cagatgcaga
   912121 ctattctggc caatcccttg gcgagcccgt tcacgctcgg catttcggca gctgccggct
   912181 tcggagcagc actcgggctc gttgccggcg ttgctgtttt cccggtcgcc gttcagtaca
   912241 tggtgccaat caacgccttc ctgatggcga tggtggcggc gcttttcatt cattttgcct
   912301 caaccatgcg cggcgtcacc gtcgaaacga tcgtcctact cggtatcgcg ctcgtcttca
   912361 cattcaatgc ggccctgtcg ctgctcgaat atctcgcctc cgaacaggcg ctcgcggcgg
   912421 tcgtgttctg gaccatgggg agcctcacca aggcaacctg gccgaaggtc tgggttaccg
   912481 ccgcggtgct gctcgtcgcg gtgccggtct tcgcgcgccg cgcctgggcg ctgacggcgc
   912541 tgaggctcgg tgaagacaag gcggcgagct tcggcatcga tgtcgggcgg ctcaggctcg
   912601 aaacgatgct cacggtaagc ctgcttgccg cgataccggt ctccttcgtc ggcacgatcg
   912661 gcttcgtcgg cctcgtaggg ccgcatattg cccgcatgct tgtcggtgaa gaccagcgct
   912721 tcttcctgcc ggcctccgtc ctctgcggct cgctgctgct ttccgtcaca tccgtcgtca
   912781 gcaagacgct cattcccggt gccgtgctgc cgatcggcat catcacggcg ctcgtcggcg
   912841 ttcccttctt cttcgtgctg atattcacca ataggaagcg cgcatggtaa gcctcgccct
   912901 caaggatgta ggcgcgacgt atggtcggcg cgtggttcta tccgacatca atacaggggt
   912961 attgaaaggc ggacagctca ccgccgtaat cggcccgaac gcggccggga aatcgacgct
   913021 gttcaagcgg atcgccggcc tggccgccgg tcccggcctc gtccatctct ccgacacggc
   913081 caagggttca gaggctatct gctacatgcc gcaggacacc ggcgccaatg ccgtcctgac
   913141 cgtctacgag tcggtcctgc tttccgccaa acagggctcg ggttggaagg tgaaggacgg
   913201 cgaactgcaa gagatcgatc gcgttctcgc ggcgctcaag atcaacgaac ttgctttccg
   913261 cggcctcggc gagctttccg gcggacagcg ccagctcgtc tcgatcgcgc aggcgctcgt
   913321 gcgcaagccg gaggtcctcc tgatggatga gccgacctcc gcgctcgacc tcttccgtca
   913381 gatcgaagtg ctcggcttca tgaagcgcct ggcgacacaa tcaggcatgg cggttctgat
   913441 cgcgctgcac gaccttaacc atgcgctgcg ctattgcgaa gacacgatcg tgatcagcga
   913501 cggctcggtg gttgcaagcg gcccgacgca cgcggtcgtt actgccgaca tgttgaaatc
   913561 cgtctaccgt gtcgaagcgc gcgtcgaagc ctgctcgcga ggccggcccg tcatcatcgt
   913621 cgacgattcc atcgctctcg gttagagcct tccaactaga ctggaaaggc tccaaggcaa
   913681 ggcggcttca gccaggaatg aaggcgaagg ctcggtcgcg ctcggacatc tgggccattt
   913741 cgagcggcta ggaaatggca agacgcgggt cgagcggatt gagcccgcct tcagactcgg
   913801 ttcgatctgg cgttctcggc gctcagtatc tcgccgtagc attgcagata agtgggcgaa
   913861 tccggcctta tgtcgatggc gacatcgaaa atgacgccct ccaggcacga aacgaacttg
   913921 gcttcgtcat gggcggccgc tggtagtgca tgccgcggat cgtccccttc tctcgcgtca
   913981 gggtgtagtt gatctgcgcg atcgatccgc cggtgccgaa gtcgctcaac tcgttccggc
   914041 agaagaaacg cgagaagacg ccgcgttcgg gtcccgtatc cgccggcgag aatgacgacc
   914101 ttcatgccac gactttcccc ttcaagctgc cttcgaccgc ggtctggcgg attgtccgcg
   914161 ccggcggttc attggagcat tttagccggg attgcaagaa atcgcggtga aggccggatg
   914221 tttgcgcccc catgtaaccc caaatgacta tggccggcca cagcgggttt gcttgccggg
   914281 tgcagggcaa aggcgcagaa tgccggccgc agctccatgt gtccgttaat cattgccgac
   914341 tgacggacct cgcgcgtccg acaagacgcg ctgcactgcg atgcaggggc gttcaccgcg
   914401 ggagagcgaa tcatgaatga catgagcctc accaatctgc aaaacggaat aacaatggtc
   914461 agcgccgcgg cgatcgaggc ttttgccggg cggctgcgag gacgcgtgct gatggcgacc
   914521 gatgccgcct atgacgaggc acgcacggtc tggaatggca tgatcgatcg caggcccggc
   914581 ctgatcgtgc aatgcgccgg agccgccgat gtcgtcaatg cggttcgttt cgcggcggag
   914641 aaccagttgc tactcgcagt gcgtggtggc ggccacaaca tcgccggcaa cgcggtttgc
   914701 gacggcggtc tggtgatcga cctcacgccg atgaagtcga tccgggttga ccagacgacg
   914761 aagacggcct gggttgagcc tggagcaacg cttgccgaag tcgacatgga gacgcaggcc
   914821 ttccgcctgg gtctgccgac cggcatcaat tcgaccaccg gtattgccgg cctgacgctc
   914881 ggcggaggct tcggctggat cacgcgcaaa ttcggactga cgatcgacaa cctgctttcg
   914941 gcagatgtgg tcaccgcgaa tggcgaactg gtgcgcgcca gcccgaccga gcaccgggac
   915001 ctcttctggg ctatcagggg cggcggcggg aacttcgggg ttgtgaccgc cttcgaattc
   915061 cgcctgcacg aactcggccc ggaggtgctc tccgggctcg tcgtccatcc ctttgccgat
   915121 gccgagagcg ttctgcagca atacaggcag gcgctcgaaa atgctccgga cgagctcacc
   915181 tgctgggtgg tgatgcggca ggcgccgccg ctgcccttcc ttccggccga ttggcacggc
   915241 aaggaggttg tcgtgctcgc catgtgccat tgcggcgatc tcgaagcagg agagaaggca
   915301 atggcgggac tgcgggcgat cggcaatccc atcgcagacg tggtatcgcc gcatccattc
   915361 gccggttggc agcaggcctt cgatcccctg ctcgcgcccg gcgcccgcaa ttattggaag
   915421 agccacgact tcatggagct gtccgaccag gcgatcggcg tcctcaccga agctatcaga
   915481 aaattgcccg gtcccgaatg cgagatattc atcggccatg tcggcggcgc cgccggccgc
   915541 gtcgccgccg aggagaccgc tttcccgcag cgcagctcgc atttcgtcat gaacgtgcac
   915601 ggccgctggc gtgatcctga tcaggatcag gtctgtatcg actgggcacg ccatcttttc
   915661 gaagcagcca agccctatgc cgcgggcacc gcctatgtca atttcatgcc ggaggacgag
   915721 atagaccggg tcgaggcggc ctatggcgcc aattatggcc ggctcgtaga aatcaagcgg
   915781 cgctatgatc cgctcaatct cttcaggatg aaccagaacg tgcggccgat ccaggaacgc
   915841 ggagcggcct gaattggccg cttcgttcgt agcacaacgg ctggaggcgt gatggaagag
   915901 gtatcggccc gcaaaatttt tcaatgcgcg gcgggacacg ccgcgcggtt ccgcgagaag
   915961 ataacggagc ttccgcaacg gccggagcta tcctatccgg cagcgctggc gacctttcgc
   916021 gaggcgctgc cggaacaggg aagcgccggt gccgaagtaa tcggcgacct tgccgcgaag
   916081 gctgaacccg ggctccacgc tatggtcggg ccgcgtttct tcgggtgggt catcggcggt
   916141 tcgcatccgg tcggggttgc ggcggactgg atgaccagcg cctggggcca gaacgccggc
   916201 aaccaccatg ctgcgccggc cgccgccgct gcggaagcgg tcgcggcgaa ctggctgctc
   916261 gaccttctcg acctgccgcg ggaaagttcc gtcgggtttg cgaccggggc gactctcgcc
   916321 aatttcatct gccttgccgc cgcgcgcgga gaggtgctgc ggcagtgcgg atgggacgtc
   916381 gaggcgcagg gcctctttgg cgcgccgccg gtctcggtac tcatcggcga cgatgcgcat
   916441 gcgacggttt tttcggcgct gcagtttctg ggtttcgggc acgaccgcgt cgttcgcgtg
   916501 gagaccgatc acacgggccg cattgccgca ccggcattcg cgggcgcagc cacgaagatg
   916561 accggtccct gcattgcaat attccaggca gggcagatca atacgggtgc cttcgacgat
   916621 ttcagcggga tcatgccgat tgcccgagat ataggcgcct gggttcatgt cgacggcgca
   916681 ttcggcctct gggcgcgcgc cgcgcccagc aaacgggcgc tgacgaagag cgccgagcag
   916741 gcccactcct gggcgaccga cggccacaaa tggctgcaga cgccctacga ctgcggatat
   916801 gccatcattc gcgatcagga ggcgcatcgt cgggcgatga cgatcgccgc gagctacctg
   916861 ccgccaagtg acgaaggcga acgggaccca agccatttcg tgcccgaact gtcgcgccga
   916921 gctcgcggct ttgccacctg ggcgatgatc aaacatcttg gccgcgaggg catcgccgcc
   916981 atggtcgacc gccattgccg tgtcgcccgt gccatcgccg aacggttgac cgtagaagac
   917041 gggataaatg ttctaaacga agtcgtcctc aatcaggtcc tcgtgcgctt cggagcggca
   917101 ttgcccggcg aagaatccga ccggctgacc caggcggcga tcgcccggtt gcaggccgac
   917161 ggtacctgtt tcgccggcgg cgccgtctgg cgcggacgca aggtgatgcg actttcggtc
   917221 atctcatggc tgacggacga tcaagcgggc gagatgactg ccgaggcgat cattgccacc
   917281 tggcgtgcgg ttcgcggtgg aacgttggtt tgaggcctcc ggtatcggaa ccactctacg
   917341 gccacttcgt tagcacataa tggagcgcga cgatgatgcg gagggccgcc gagccgattg
   917401 ggggtctcgc gccgcagcac tcctgacgcg caatccaggg aggagattca aatgtcacga
   917461 atgaaatttc ccgccgcggc cgctcttgcc gctctcatgg ccatcggcac cacaagcgcg
   917521 gcagtcgcgc aggcacccgc tccggtaccg ccgacggggg aaatgccggc cacggaccag
   917581 gtcatcgagc cggatatgcc aaccggcgat gaggagggga ctggaggggc tgccctacag
   917641 gaacagccag acaggatgcg cgaggacatg atccgaggcg acggaaagcg cggcgaccgc
   917701 atgcacggcg atcggatgcg gcaccgcgac cgaatgggag gcgcgatgat gcaccggcag
   917761 atgatgcatc ggcagatgat gaaggtcatg ttcgccatca ccgatgcgga caatgacggc
   917821 gccctttcct tcgaagagat cagcaccatc cataaacgga tattcgacaa ggtggacatc
   917881 aaccgcgacg gcaaggtcac gccggacgag atacagggct tcttccgtaa ttaggaaggc
   917941 tcagttacgc tcgatgaagc ggttctcttc tccggagtgg ttcgcccgac cggggtttct
   918001 cgcggagttc gaatggcatc actcctgttg aagcgggtct acgaggcgcc ggaggcgtcc
   918061 gacggcatgc gcgttctcgt cgaccgcctt tggccgcggg gcatcgccag ggagaaggct
   918121 gagatcgacc tctggctgaa ggacattgcc cccagtgacg cgctacggaa gcgcttccat
   918181 gggaagcccg aggattgggc cgcgttttgc gcgaactatg cggaggagct cgagggcgcg
   918241 gcggcgcagg cggccgtcgt ggagctaggc ggcctgatgg cgcgcggacc ggtaacgctg
   918301 ctttacgcag cgcgcgacga ggcgcgcaac aatgcggttg cgctgaaggc atggctggtg
   918361 cggcgagggg tcgaagcttc ttaaatcact atgatttcag gccggatcgg cctaaaatca
   918421 ttgagcaatc gattctgaaa ggcagagcgg gatgcggcgg taataagcgc gcaccgtctt
   918481 ctcatcctgc tctgaatgcg ttgacagcga ccgcccttgt tcacgtatca aacaggccct
   918541 tgttgccagc atcagcaagg gcatgcggta gccgcatagg tgccattcct tgcattcgca
   918601 gtgcctgata ccgatctatg cagttaaagc ttcgaccccg tactccaaca atgaccgtgg
   918661 cacatatccg tccggccgac ccgccgcgcg tgacgaatgc cgccttgatg ataaaaggag
   918721 ccagcaatgc gggacactgc caagaccctg aacgacatga cgccgcgcga gcgcgccaac
   918781 ttgatgaccc tcgtcgcgga cgcgcttgaa gcgaccgcgg atgaggcgca ggaaatcggc
   918841 gatgagcggt ttgcagcaaa ctcgatcagt ctcgccagaa tcataagtgg ttgtgccgaa
   918901 gacgtcgcga caatggatct cccggctgca gaactactct tacagcacgg tatttcgctg
   918961 attgcgctgt tccgggatgg agcgcggccg gttctgcatt agttcacaac gattcaggtc
   919021 ggatcgacct tggtgggcgg aactgtaccg cggcacgccc aggctacgtt cgcaaaggag
   919081 cgggggccgt cggggccgcc ggcctcatag gcgtcgcgta cggcggcttc cgtgcgcgat
   919141 cgctcctctg cgtcgagcac cgccacatac ttgccgagcg gcccttcgcc ggcggcaatt
   919201 ggcgcccagt aatcatcgaa gttccgatag tccatgcgga tcatcagttg ggtttccgca
   919261 acgtccatga gcccctgcgc agcaaaagcc cgtttcatct cttccggttg caccatcggc
   919321 tgaaagcaat agcgggcgcg caactgccgc ccgccctcac tgagtgccgc caccgtatcg
   919381 accatcatgc gcatgccggg cattccgccg agatggtccc agaccgccgc cgcgacaact
   919441 ccgccgctcc gcacgacacg gcgcatttcg gcgacagctt tgccggattc gggcacgaag
   919501 tgaaggacga gcagggcgaa agcacggtcg aaacttccat cgtcgaaggg caaagcgcag
   919561 gcatcagcct cctcgaactt tatgcgcgga tcggtgttgc gccgggctgc ctccgccaca
   919621 aagacgggcg aatagtcgat cgcggcgatt tctcggagat tggctgcctt ggcgagcgcg
   919681 aaggtgaggc tgccggtccc acacccgaca tccagaaccc tctcgccatc gccaatgcct
   919741 gcaaagtcga tgaatttcgg cgcgagctta cggctccagc gccccatcaa ctgttcgtat
   919801 ccggccgcat catgcacgtt gaagctggat gtcatcgggg cctcccttgc cgcgccttca
   919861 atctaaagcc tttcttgtct aaatggaaac attccgccgg agcagattgt cgacggtcgt
   919921 acccgaaagc cgagcggcga aaagcggaag ccagctttcc tcattctgca gttactctct
   919981 atggttgcaa taagcttacc gatcgcgtaa tcctcaccaa tggggcgtag atatcggggg
   920041 gcattgtgag gggggttatc tgcgtaaggg gtgtcatctt tggtattctc ctgtccatgt
   920101 atgttggaga atacttatgc ggaggcgcgc tcgctgcaga tgtcggggtc gtcacctggc
   920161 gtgaacatcg ggtcgtcaag ctcaccggtc cgatcgaccg gggcaaggaa cggaaactgg
   920221 cagcgcacct ggctcaggct gaggccttgc cctacggatt acctgttctg cttctcgaca
   920281 gccccgacgg gtcggttggc gaggcacttc ggatttcatc gctcctggat agaaggccgg
   920341 ttcacaccgt cgccggacgg tgcgagatgc gcctctgcct gtgcctcgat cgttttcatt
   920401 gccggtaaga cgcgcacggt cgaagatcgc ggctcgctgg ggcagcattc ctgttcccgc
   920461 gggggcgtcc cggacgaagc ctgtaacgag gctatcagtc gacatgcggt gaagcatggc
   920521 gtgtctcacg gcagcatcgc tgcattcgtc acctatgtcg caccggaaag catcctctgg
   920581 tcctcccgag aggacgccga gggctggggc ctgacgaact atccgaccga agacctgagc
   920641 ggctttgtga gaagcgaacc gcgggtgctg aaagtgttga ccggcgaaat gcccctggcg
   920701 tagtccgcgt ggcggatcaa tttccgtgat gatggtttcg aggcattcgt cagaaccgtc
   920761 tccgatgtcg aacgtgagat gcaactcaac gtcttctgct ccgagaaaca gcccggccgt
   920821 ctcttcctgg gcatggaagt caacgggccc gtcggtgtgg tccgggaggt cgccctcagg
   920881 gtcgccgtcg agactgagag gaccttctgg gccgacgccc ccatcattca tcagaaggac
   920941 agtcaaattt ccgagatcgt tacggaagtt cccacggaac agttaaaggc atttctgaca
   921001 aaaacgaaaa ggttggcatt cggggtcgct aaaaagcagc cctaaccagc cgatgatcgc
   921061 tgaggcctgg ctggaaaaca gccgcaaggt tttgctgttt gcagcgaaca actgcgttga
   921121 cgccgctgga cgatgaagcc gagccaaact gcggtgcctt ggcgcaagtg aattccctcg
   921181 gcgaagtctc tctccaggca tcgacctgtc ttgaaaaaaa agcgcagcga attcgatcat
   921241 gctgtcggat cgctggcggc tggtgcgtca ttgtatgatc aggtcgggct ctcgatctga
   921301 aggacaacca tcaggaggac gacacgatgt ctaagaatac catttgtctg tggttcgaca
   921361 aggacgctga ggaagccgcc cgcttctatg ccggcacctt cccggacagc aaggtcgaag
   921421 ccatcatccg cgcgcccggc aaatacccgg acggagaaga gggagatgtg ttggttgtcg
   921481 agttcacggt ggcaggtgtc gcctgcgtcg gattgaacgg cggcccgaca ttcaagcaca
   921541 atgaagcttt ttcattccag atcagcaccg aggatcagga cgaaacagac cgctattgga
   921601 acgccatcgt cggcaatggc ggccaggaaa gcgaatgcgg ctggtgcaag gacaagtggg
   921661 gcatctcctg gcagatcaca cctcgcactc taatggaggc gcttcaagct ggtggcgaac
   921721 aagccaagcg cgcattcgac gcgatgatga cgatgcggaa aatcgacgtg gctgtgatcg
   921781 atgcggcacg aagaggggat gacgcgcgat gaccaccgag acgatcaaag gacctgcttc
   921841 ctattttcca tcgatcgaga agaaatacgg ccgtccaatc gatgactggc aagagctcgt
   921901 acggaagcgc tatcctgcca ggcacatgga acttgtaggc atgctgaaga gcgagcacgg
   921961 cattggccac ggccatgcca atgcgatcgt ggcgtacact ctcgcggaag acaagcagcc
   922021 agcctcttga cggcgtgtgg tgcaagacga accgtaatgc tgcttccgac ccgaagccca
   922081 ttcgaccttg tttgatggag gttcagcagt cctcactcga tcagaagtgc ctcaccggta
   922141 aaccacctca tgccgattac catgacggga agcgccgcca gctgctgctc gcggccccgt
   922201 cactccgcga ctatatcgat cttcgtggtt gcgaagcgct tccgcaacca ggtcgcggcc
   922261 ggacccgtgg ggcgttgttt gtgccagacc agctccagcg ccaccggatg cgcgccgtcg
   922321 tcgaattgaa gcgccgggat cgcgagatcc tgcgcaaccg gcgacctcgc aatgatatga
   922381 gcaggaatga gggcccagcc gataccctgc tttagaatct gcaggatcac ccaatggctc
   922441 tcgacccacc agacttcggc tgccacgcga aggcggtgcc gctccatacc ttctgtgcgc
   922501 accgtgacca tgatctgccg atgccgcttg agatcttccc agtcgaccac cgaattggcg
   922561 agcggatggc tcttggcgca gaccagattc aactgcaccc agccgatcgt atggaagccc
   922621 agctccgcgg gcagatcctc ttgccgccac ataacgccga tatccgcttt cccgtcaagc
   922681 acgaggcggc tgacgtcttc catcatcggg aacagcagtt cgagctcgac atgagggaat
   922741 tgcacggcaa actcggcaaa cagctcgccc aacgcatgct caggatacag ttcgtcgata
   922801 gcgaccacga ggcgcttttc cacatgcgct tcaaagctgg ctgccacgcc gatcagatgc
   922861 tcacgcctgt cgaggatcag cttcgcttcc gacaacagcc gctcgccggc cgaggtgagg
   922921 gtcgggttgc ggccccgcct gctgaacagc tccagcccga gatcctcctc aagggtcgat
   922981 atctgcgtgc tgacggcgga ttgcgccttg cgcaatgccc ggccagccgc cgagaaggat
   923041 ccgtgctcgg ccgccgcgac aaaggcttcc agctgttcca ttgaaacggt catctatctc
   923101 atttccagat aggatctaac tttgtggcgc caggaataga gatataaagc gcgcagatca
   923161 acacagctca aaaggagatg catcgtgaag atgcgcacgt tcccggaccg gatccggcac
   923221 actttgttgt ttgaggtcat cggcttgatg atcgtcacgc cgctcgcggc ctatctgttc
   923281 cataagccga tcatgcatat gggtgtcgtc ggcatcggct ccgccacgat tgcgacgatc
   923341 tggaacttcc tgttcaacct cggcttcgat cacggcatgc gccgtatgtt cgggtccact
   923401 acgaagacct tcagaatacg tctcgtgcac accgtgttgt tcgagatcgg cctgttggcg
   923461 atcctgctgc caccaatcgc ctggtacctg aacatgggcc tgctcgaaac attgcagctc
   923521 gacctcgcca ttgtagcctt ctatctggtt tataatttcg tcttcaacct cgcctatgac
   923581 cgggtcttcc cgatcccggg cgcgccgcga gccgaatacg catgaaagcc tggggagggg
   923641 gaataggtac gcccgcgagg atcagtgcag ccgcaaagcc tccagcaggc gctggtaagt
   923701 cggcgccaga cgcctgagca ggtctgccgc ttccgcgtcg ttgccggcga ccaggggata
   923761 ttgcaatgcc ccagtcaggg cggcctgctc cgaggcaata tgagcagcgt ccgtatagtc
   923821 gatccgggaa aggcaagtgg cggcatcggc gagccgtctt gcgccaacgc ggattgcgaa
   923881 atggatcagg tgtgcacgca agtcttcgtc gcaccccgcg tcgatcatgc tcgccaatgc
   923941 ctcggccgcc tcgccattgc cgatggtgcc ttcgggcatg tgtcgcggct cttgcatcga
   924001 caaccatctg atcgcggcag gcagcgacgc tctgatttcg tcatcttcgt cgaccacgcg
   924061 catctgtcgg aaaccgaaac gcatggtgaa gggcgttcca tagtcgatgg tttccgcctg
   924121 ccatgcggtc aggaaatcgc cgatcggcaa tgtcgcgaat gggtatccct ggggatcgtg
   924181 caactgcacc caatcgttcg cgaggccgat gacgacgaca tagtgatctg cgccgatcgg
   924241 gccgtccttg cccggttggt gccgcagcca gcccatctct accggaccga cccagactgg
   924301 gctatggacg agctcggatc ggagtcgctc gactgcgtcc gcggcattgc cgccgctcgt
   924361 gacagatgac gtccagccca tggcatcgag agcagcatcg aagccagcct caggcgtcca
   924421 gccgaaggga tcgaaaaagg gcaggcaccc gccgacgagc tgcatcccga aagggctgcc
   924481 ggtggcgaac tcgataacag cggtggatgg agcgtgttgg ccaaacatca tcgcgaacgc
   924541 attggcgtag caatagggac cggagcctat atacggaaaa tgctgcatga acctgcgcct
   924601 ctcaaatctg gttgcgaggc aatgcaagag gggcattttc atcaaaattg tcaaccgctg
   924661 gatttgccgg cacgtgacag ggcgcctgtg aaccgagcgg cgatggcaag gcacgaccaa
   924721 gcctatgctc gtggcggccg ctgaatctcc accggcgtct tcatgatgat ctctcgatgc
   924781 gggaagggga ttgatacctt cgccgctttg aacgcatccc ataatgccag cagaacctgg
   924841 ccgcgtacat tcgtcaaacc gttggccgga tccgagatcc agaagcgcag gcggaaatcc
   924901 agcgaggagg caccgaacgc cgtcatccag cagacaggcg ccttgtagtt gttggcgacg
   924961 cggggaacgg cagatgcggt ttcgatggca atccgcacca cctcatgcgg atcgctgtcg
   925021 taggacgtgc cgaaatcgac gtctatacgg acgtaatcgc tggagaagga ccagttcacc
   925081 acctgctgcg agatgaagtc ctcattgggg atgaggaatt ccttcccctc gcgggtgatg
   925141 accgacacaa aacgcgcacg caggtcgcga atggatccga acgtgtctcc aagcgtgatc
   925201 gtgtcgccgg gcttgatcga cttgtcgagc aggatgatga tcccggaaat gaaattggat
   925261 acgaccttct gcagtccgaa gcctactccg acaccgacag cacccgaaaa gaccgttagc
   925321 gccgtgaggt cgatacccgt cgcggacaat gcgattgcgc cggcgaccat gatcagaacg
   925381 atcttgatga gcttgctgat cagcactttg aacgacggcg aaaggtcgcc cgaacgttga
   925441 acccagtggg aaagcacgtt gccggcgagc actgcgaccc agatgagagc gaccgtcaga
   925501 acgactgcct tgaggacgat cagcagcgaa aggcgcatcg cgcccagatt gacggcggcc
   925561 gcgtccagcg tcgacagggc ggggccttcg aggccggtgg cataaaccgc aaggtagccc
   925621 cagctcagga cggcgaccac gcgcgacagt gtctggttgc ggatgatctt ggtcagcacg
   925681 gaaatgacga accaggcggc cgccagagtc agcgcggtcg agacaagcca tcgctgcgat
   925741 ggccacgtac tctgtgtgag aacgacgttg gcaagccaca gccagatggt cagaaaaagc
   925801 catttcaggc ggcgcatgaa ggcgatgatc acacgcagca gatccgggtt gcccttgatg
   925861 cggcgagccc tggtctccaa tgccggctcg gttatggagg cgacgaggga ggcgaaaata
   925921 taaccggccg cgattatccc aagctggtag aatgtccatt cgctgagcac gaatgtccgg
   925981 aaccaggcct caagcgggcg aaaaatctgc acgaaatcca cgactgagcc tctcgagata
   926041 gcttcgcaat ccaaccttcc ggtttagtaa tgttagaccg aagcagccgt gtgcaaaagc
   926101 atagtcgtct atatctatgg cggcgggacg attttcatca cccggacgcc ctcgcatgat
   926161 ctctcccgac gtggttcact ttccgatctg atcttcgatc gctgttttat cgatgacgga
   926221 aaatacatcg gcaatcttgc cgtttgtcac ttcataaaac acgttttctg cgaaggagat
   926281 gcgccgacca ttgattgcca gtccaaggaa actgcctttc ggagagcagt cgaacttcaa
   926341 tcttgcagcg atgaggggcg gttcgcaggc caaacgatcg atcttgaaaa gcaggtcggg
   926401 aatatcctcg aaatccttta cgagcatcga ccgatagcca gacagtccca agagacggcc
   926461 attgtgtctg acatcgccgg caacataccg tccaagttga tcccagtcct gtcgattcag
   926521 gcaatcaatg tagtcacgat aaaacgcgtg cagcattata tcccttcctt tgcgggcggc
   926581 ggggccgaag cttgggagtt tcgccatctg acgactggcg gtccagtcat cgcggccggc
   926641 ctggtcagcg aggtcgatta cgccgactgg ccaagccgct tgagaccgac cggaagggga
   926701 aacagcgcgg tcgagcgcgg cgcagcccga ccaaacagcc gctcgcttca gtcaacccgt
   926761 aggccgacgg cacgatgttt ccttgcgata ggagaagccc cacatcgggg ttgccgtttc
   926821 gatcgatgcc ggagacattc tggtgttcgc gaacatatgc gatggctgct gcctctaagc
   926881 ctgcgagtgc ccgcgcgggg gactggcgcg ggcaccgcca acaggttggg ggacctgaat
   926941 gccgaattgt tcggcagcac attaattctc aaggcctgcc tttgttcccg cacgcgaagg
   927001 agcgtaacgc attaattccg aagtgctccc aacggcaacg cgacggctgc cgcagctact
   927061 gttgctgcgg caacgggagt atggttttcg tcttgctctg ggtcggcttc tctcccggca
   927121 catgggacat ggtctttgtc cggctctgca gtccatcctc tgtgaccttg gtcttggtct
   927181 gcgacttgct gaatgtgccc ttgtccatgg cctgagcctt tgattgtccc tgcaactgcg
   927241 agggattctc atttatcttt gtccgactct ttgccttttc gtccgatgtt gcggcgcttc
   927301 cgcctgcgcc aatcgaagag gtcgttccgc tatcggttct gcatgtgccc gcggttccga
   927361 ccgtgctggc cgaggtgccc ccggccgctg cgctgccgcc ggagccgata gttccggcgg
   927421 cgtcgcattc ctgagcggcc gccggcgtcg cggcgaccgt tgctgacgcg acaaaaattg
   927481 caagcaacga ttttcgaagc atgacagctc ctttcagttt ggcttgataa ttgcgcaggt
   927541 cccatccgaa cggcgcgtga tcgttgtgcc gtcggggcgg gtcacgctcg cggtcgcgaa
   927601 gctctctcca tcggaggatc cgctcgtcgc cgaggatccg gcgctgctgg tggcggaccc
   927661 gccgctcgca gccgcaccgc cgccgaccgt ggtggacgag gatacgctgc cggagccgac
   927721 agtgacggac gacgaaacac cgcctccttc cgacgattct tgttcgatga tcatgcaagt
   927781 agagccgtca tcgagcttga tttctttcgc tcctgcatgg tcagggacgg cgatcatggc
   927841 cgcagataga gccgtgacga ctgggatcat gaatgaactg gaggtcatcg ggtctcctcc
   927901 catctggaaa acgctggctt cgggcgctcc gaagccagct gattgacgtt agcaggacgg
   927961 gcgatcgccc gtggagccgt ccttcttggc caggccagga ggacaattct tgttgctctc
   928021 atcgtcctgg gcggcgtctc gggcactgtt ttcatcgcct tggacgctgc ctgtcgtctc
   928081 atccgaaggt ccgtcagctg atccagcagc cgaaccaccg gttccgacgg aactgctcga
   928141 gcttccgccg cctgcagagg agccaccagt accaatggtc gaagcggagc cgccgctacc
   928201 ggagccggcc gcagagcctc ccgtgccgac ggagctgctg gacgtgccgc cgccggcaga
   928261 ggatccgcct gttccaagcg tagatgcgga gccggattgg caatcgctgg tgccaggatc
   928321 gcaattaccg ccagccgagc ttccgcctgt cccgacggtg ctgctggacg taccgccgcc
   928381 ggcgctggtg ccgccggtcc cgatcgtcgt gctcgattgc gcgaaagcgc cgagcgtggt
   928441 gcccgcaagc aagcctgccg caagggccgt cttaatgaaa aaccgcattg ggggttcctt
   928501 tcctcaattt aaggtcttgt ggttgcaacc ttgcatacca acccggacca gcatgacgtg
   928561 ttccgggctt ggacctcgga ccgaaggtgc gctggaaaaa agtctgaagg ctccatcgga
   928621 ccttagcccg tcagatgcgc gaataggtcc gagcgtcaat ttcggatgca acgccctggc
   928681 gacccgttcg ttttattccc ttggactctt cttcattctg gagccgccgc gggctgcgtg
   928741 tgattgccgt tcttcagcat tcccatcact cagcatgtga tctgccagac tgtagcagtg
   928801 gctcgcctga aaggcgttcc gtccccggtt catgtgcgtc aggttgaacg tccggatcgc
   928861 ccgcaacgct ctgctctgcg cgatgaattt gcagatcgac gagaagccgc gggccttgat
   928921 gccgaatatg tcctcgccgg gaggaaagaa atagctgacg tcttccggtg ttacgacaca
   928981 gcgctcaata aaagcatcgt ctacttgccc gtgatcgagt gaatgatcgg tggtgaaatc
   929041 ggaaagatgc accaggaaaa gcgcgcgaat gccctcgccg tcggcataaa gcgagaaaag
   929101 ctccatccag ctcgcattga tgcgaacgag cgccttgccc ggcgtcgacg gtagacagga
   929161 gaccgaccag tagtggcgct ccgttcggtg cgggatcggg atgcagtcgc ggccgtagcg
   929221 cctgagaacc tccagaacct cgggcgcctg ctgccggcgc agcagtttct cgaaccgcgc
   929281 ggcatatttg aaacgcagtt ccatggattg cgaacgctcc tcggcgtcgg gcaggatcgt
   929341 cttgccgtct atccaatcgc gctgctgctg gagatccagg aattgccgca gaccggtgcc
   929401 cccttggctg cgagcggcgc tcatcggcgg tccagcagtc gagcgactgc ctcgcggaca
   929461 agggcgggga cgctttcagc gccatccaga taggcacttt ccaggagacc gtccgagagc
   929521 gcgacgagga gggaagcggt gacggaagga gctggatcgc cgtcctctgc cagaaggttc
   929581 tcgaggctgt cgtgatacca agcgcgacgc gcatcgatcg cctgccgcac ggggctggcc
   929641 ggatcgggat actccgccgc cgcattgagg aacggacacc cccgccagcc tcccgcggtc
   929701 acggcctcgc tgatacgtcc catgatcgca gaaatcgctt tccgaggagg ttgcttcgga
   929761 agcgcggcca ctgccgcccg gccgagccga tctatctctt cgagataggc gacgacgagg
   929821 tcatccttcg agggaaagtg attgtagaag gtcgccttgg cgacaccggc ttcggcgatg
   929881 atgcggtcga taccgacagc atggattccg ccctcgtaga aaagccgtgt cgccgcgtcg
   929941 agcaaacgac gacgcgcgga acttgcttca ggctggttct cggatttctt ttgtctcatc
   930001 gcttgacgct aacagacagg tctgtatatt tcaatagtag acagaccgat cggtctatat
   930061 agcgctggcg ttggaccggt caggcgtttc ccagcgatga cggcggctat ttcgttaaag
   930121 gaggtgcgta aaataagtga aagcaatgtt acccgcgaaa tcgtggaacg cttcaacaac
   930181 gcatttgaga agcatcgccc cgaggacctc gatgatctct tcggcgagaa ctgtgttctc
   930241 gaaaatacgg ccccggcccc ggatggagcg cgctacgaag ggcgcgaggc ttgcctcgct
   930301 ttctggaagg gcattgcatc gtctgccgac ctcgtcttca aagccgagga tatctccgtg
   930361 atgggcgatc gcgggatcat ccgctggcag cttcgctgga gcgagcgcga agcggatcgg
   930421 attcgaggcg tcaacctcat gcgcgtccgg gacggaaaga tcatcgaggg tctgggatac
   930481 gtgaaggggg gctgacgttc tgctcgcgca ccggcgatcc tctcgggtgg ctgccacgtg
   930541 gatgtaactc ggtgtatcaa ttccgtcagc ggcatgatgg ttaaatcgaa cggctgtcat
   930601 atgcccaatg cagcagagcc tggcgctgcc gcggccggca ccagcaatcc ccaggctcgc
   930661 aggctcggcg aagctgagcg atatggcggc gaagagcttt ccaacgggcg atctgtcgct
   930721 cgtcctcgcc gggcatgcga cgaccttggt ggtagcggca gtaccactgg aaccagccac
   930781 gcggatcttc gggatgtatc catcccttcg ctcgccaaac gctgagcggt tggctggcgt
   930841 cgacaccgaa acagttaatt gacggatctt ttcgcagcga cgacagccgg gcccctacaa
   930901 accagctgtt ggggaattcg tcgcgacaat cggtcatgta cttgccgccg aacacgccta
   930961 gcgcaagcat ctcggcgggt gttaagtctg gccggaaatc ggcatgaaag tcgcggccga
   931021 ttggcgcaac gagagcgtac cggtagcctt gctgcatccg atcattcacg acgacccacc
   931081 gggctctcat cgggcactct gcgacagtgt tttcgaaggg ttacgccgcc agatggataa
   931141 gttaagtgcc gctgcaaagc tcacccacgc caggtaagga acaagcagca aggcagcagc
   931201 cgcattcacg gggtgaaaca ttacggtcgt cgccaggatc gcagcccaaa gcaccatgat
   931261 ctccaccgcg gccagcccgg gtcggtgaag tccaaaaaag atcggcgtcc acgcagcatt
   931321 gagcagaagt tggactgcat agacaccgag aggcagtgct gcgccagcaa tgcctgcctc
   931381 ttgccatacg agccagcccg acagtccaat cgatgcatag agaaccgccc agaccggggc
   931441 gaatagccaa ttgggcgggc gccatcgtgg cttgttgagc tgcttgtacc agtcgcctgg
   931501 cctaaagatc acgccggtag ccgccgcagc gaagctcgcg acctcgaagg cgaccagcac
   931561 gagaagggaa tgcatgtcca tcctgcaaaa gatggagggg cccgccggcg aggcaagcga
   931621 ggccctccat tgtccctatc ggttctggtt ggcagcgaat gcgccggagc ccatgacaga
   931681 aaacagggga atgatctgcc aggccgccga tagccctacc aggatgtaaa cgatccgggc
   931741 gagccccgag ccagccccga agatggcggc cacgaggtca aagccaagta gtccgaccag
   931801 accccagttc agtccgccta cgattacgag aatgagcgtg aaaatattaa taaaattcat
   931861 ggttcttctc caattcgagg atgagaggtc agccttccgg cggcatgatc accttgtcga
   931921 tgacatggat gaccccgttc gaggcagcaa tgtcggcagc agttacggcg gcgtcgttga
   931981 ccttgacgtt ggagccctcg acctcgatgt cgatcatttt gccatttacc gacttcgctt
   932041 catcgatacc cgccacgtcc gaagccatga cctttccggc gaccacatgg taggtgagga
   932101 tctcagcgag cttttgcttg ttctccggct tcagcaggtt ttcgacggta ccggccggca
   932161 acttggcgaa ggcttcatcg gtcggagcaa agaccgtgaa cggacccgtc tctttgagag
   932221 tggcgaccag gcctgccgct tcgagcgcgg cacccagcgt cttgaattga cccgcctcca
   932281 tggcggtgtc gacgacatcc ttgtccgcgg cgaacgcgct gacactgcct agcgtgatcg
   932341 ctgcagcgaa caaaaggcta ttcaacttca tggcatttct cctctcgata ccgggtgcga
   932401 attgcaccgg gttctttcat gtggtgaaaa catgttttct taccagtaaa attgtcgtga
   932461 gcagaaaggc aattctcttg tgaggacaaa tgtcgctgtg atagtttccc gaaacgaaaa
   932521 ggagtttgcg acgtgctctc tgatacgctg tctaacgagc tccagcgcta cgcaatcggc
   932581 cctcgtatta aggccctgcg cctgagaaag aagctgggac tggtgcagtt ggctggccat
   932641 acagggctct cgcctgcgat gctctcgaag atcgagcgcg ggcagatgtt tccaacactg
   932701 cccacgctgc ttcggatcgc catggttttc ggcgtcggcc tcgatcattt cttcaatgtg
   932761 gataaggagg agccgctcat cgcgattgtc cggaaggagc agcgtctcaa acttcctagc
   932821 ccgccaggcg agaagcaccc agcctttcta ttcgaaagcc tggactatcc cgcttctgac
   932881 cgccgcatgg atgcgttcta cgccgaattc ccggtcgatt cgccgccctc agagccgcat
   932941 caacatggca gcgctgagtt catctacgtg ctcagcggtc ggcttatagt caatgttaat
   933001 ggcaaggagt gcgcgctgga tacgggggac gctgtgtatt tcgactcgag cgttccgcac
   933061 agttaccgcc atgaaggcaa agaaatctca accgcgattg ttgtgacttc ataggccgcc
   933121 gttaactgag tatccctgaa actcatccca atcagcagcg aagcaaacgg ctgctgctgc
   933181 ctcgtagttc gtcgggactc cccggtcttc ggtcgactat ttcaagaaac cgtcggcatc
   933241 gaactcgtcc catccgcgca acggagacga ggtcgatcca tccttcggcg cgggcttgtc
   933301 cttctttttc ctgagtgatc tcgtcagctt cgccttcatg gccgactgac gacgtttctc
   933361 ggctactgcg acaatatcgt attcgcgcca ttcatcgacg gccccgcgat cgagaatgtc
   933421 catgaccacg gccggatcga atacgtggaa ggttatctga cgcgcacgcc cgcgcagctt
   933481 gaccgtacgc gttccggccg acggtagacg gccatcttgc agccagcggc ggcgttccga
   933541 tgtcgagatc gccagaatat cctcgatctc ccgggggatg accgggaggc tttccatgtc
   933601 ggagagcatt ccagtgacgg atgctgaggt cgcgcggaaa atcgctctcg atgtgtccgg
   933661 catcgacatg gtcaggaccg cgctttcaag aaccagtgcc ttccgaactg cgagaggaag
   933721 ccgggcgcgg atttcctgca agataccttt ggcgcgaacc gccgacccga gcgtcaccga
   933781 cgtcgggagt gaccatgtct tgataagctc ggagtcgacg tactgtttat gctttgccat
   933841 ggatgtagag atggatccgg cgggagccct cttcaaccgc tttgctggta ccgctactca
   933901 attcttcagg gggcgcggct cttcagggcg cgcggccagt tcatgagcgg gtaccgccct
   933961 gttgaatgct cgacatcctg cttggggccg ccccgcgcga gatgcgatgc acgtagccga
   934021 cacctttctc atggacgtag tcgtcgtcgg tgagaccttt cttcggcagc tgccggagtg
   934081 atgacccagg gtctctccac ctcctagctc cgatgacgga gtgcttcgac gatgacggtc
   934141 attgccggag acatttggcg tctgctcgga tagtacagat ggtagccggt gaaaggctgg
   934201 ctccagtcgt ccaagacggc ccggagtctc cccaccgcga ggtgttcttc gacaagattt
   934261 tcagggacgt aagcaattcc gtacccctcc aaggctgcct cgacctgagt gatcgaagag
   934321 ttgaagctga gttgcccgtc taccctgacc cgcagttcac gaccgtcctt ctcgaactcc
   934381 catgaataga acccgcccca tgttgcttgg cgcatgttga tgcatacatg cccaaccaga
   934441 tcctgcggcg tggttggaat gccatgcttg gtgaagtatt ccggtgacgc cacggctcga
   934501 agacgccagt ccggactgat ccgcactgca atcatgtcct tgtcgacgct ctccccgagc
   934561 cggacaccag catcgaagcg ctcctccacg atgttgctca tgccgttgtc actgtagagc
   934621 tcgagccgaa tgtcgggata gtctgagagg acgcggctca gcttcggcca taccgtcgtc
   934681 tgaagggcat gatctgacaa cgtaagtcga accgtgccgg atggcttttc ccggaaggcg
   934741 acgagtgccg ccagatccgc ctcgatctgc tggaatcggg gagcaagcga ctgaaacagg
   934801 cgttctcctg cttccgtcgt cgccacactg cgcgtggtcc tcgtcaggag ccggacgccg
   934861 aggcgcgctt ccaactgctt gatcgtgtaa ctgagtgtcg actgcgacgt tccaagcgct
   934921 gccgcagcct tggtgaagct ctgctccctt gccacctcca ggaaccaaag cagatccttc
   934981 atatcctcgc gctgcatcgc tcgcccctcg attaatattg agtttcgata ggtccatccg
   935041 gattagcacg gatagttcgc aaagtccgtc ggcattatct tgttctcgga ggcagaaccg
   935101 gaatgccaat cgggaccgac accatgacgc tgacctacaa cgagaacatc catagcaggc
   935161 ccagggcctg gggcgccgtg ttctccatga cattgtgcgt attcgtgctg atcgcttcgg
   935221 agttcatgcc cgtgagcctg ctgacgccga tcgccgctga tctcggtgtt tcagaaggga
   935281 gtgcgggcca ggcaatctcc atctcaggca tcttcgcggt tttcaccagc ctcttcattg
   935341 ccgcgctgac ccggcggctc gatcggcgcg tggtcgtgct ggccttgacg tttctgctga
   935401 tgctgtctgg ggtcgcggtt acctttgcgc cttcctatcc catgctgatg ctgggtcgcg
   935461 cgctgcttgg aatttccatc ggcggcttct ggtcgatgtc cacgtcgatc gtgatgcgtc
   935521 tcgtctcccg cgaccaggtg ccgaaggcac ttgcactgct caatgcgggc aatgcgatcg
   935581 cggccaccat ctccgcaccc ctgggaagtc tcctcgggtc ctatatcggg tggcgcggcg
   935641 ccttctttct cgtggttccc gtgggcttgc ttgcgcttat ctggcaatgg atcagcctgc
   935701 cgacgctttc gccccggcgc gatggcgcat cccggaacgt cctccggctg ctggcgcgtc
   935761 cacccgtcgc attgggcatg gcagcaatcc tgctgctgtt catggggcag tttgctttct
   935821 tcacttatct gcggccgttc ctggagcagg tgacccacct tggcatcgag acgctctcgc
   935881 tcatgcttct cgtgatggga ttgtcgggag tggccggaac atcgctcgtc ggccggctgc
   935941 tgactcatcg cctgttcagc attctcatcg tcattccgtt cctcatggcc tgtatcgctt
   936001 tggcaatgat tggcatcggt gagatgagga cccctgtcgt catgtccctc atcggttggg
   936061 gttttctcgg gaccgcagcg ccggtggcct ggggcacctg gctgagccgt gttcttgccg
   936121 atgatgctga ggcaggcggt ggactccagg tcgctgtgat ccagctcgcc atcaccgccg
   936181 gagcgtctct cggcggactt ctcttcgacg ctctcggctg gtggtcgacc ttctcgctca
   936241 gcgccctgct tctgttcggc tcttccctgg cgtccttcgc cgcatggctt tcggccagga
   936301 gagcatcatg agcaggaaaa cactctcttc acatcgaatt ccggcggcgc cgtagctgtc
   936361 ccgtccctgc accactaccc caatggcaaa ggagattcta ccatgagcga gcacgttgac
   936421 acggacgacg tttgcaacac cagcaggcgc aacctgatga agggaacagg cctcgccgtc
   936481 gcggcgataa gcatgatccc ggctgtgacg gcaacagggg cgttcgcgca gagccctgcc
   936541 tgggacaagg tgtttccgaa aagcgagaac gtcgatcacc agaaggtttc gttcaagaac
   936601 cgctacggca tcacgatcgc cggcgacctc tacctgccga agaaccgcgg cagtcaaccc
   936661 ttagcagctc ttgcggtcgc cggccccttt ggtgccgtga aggaacaatc ttcgggattg
   936721 tacgctcaga ccatggccga acgcggcttc gcggcgctgg ccttcgaccc ttcctttacc
   936781 ggtgaaagtg gtggcgagcc acgcaacgtc gcttcgccgg acatcaacac ggaagacttc
   936841 agtgccgcgg tcgattacct gggactgcag cccaccatcg accgcgagcg gatcggcgtg
   936901 atcggcattt gcggctgggg tggcatggcc ctgaacgccg tcgccgctga caagcgcgtc
   936961 aaggcggtcg tggccagcac catgtacgac atgacccgtc tgatgtccaa aggctacaac
   937021 gacagtgtca cgcaggagca gcggacgcag acgctggagc agttgagccg ccagcgctgg
   937081 gcggacgcgg agaagaacgg gccagcctat cagccgccct acaatgtact caagggaggc
   937141 gaggctcagt tcctggtcga ctatcacgat tactacatga cgccccgcgg ctaccatccg
   937201 cgcgctgtca actccggcaa tgcctggacg cagaccacgc ccctgtcgtt catgaacatg
   937261 ccgatcctga cctacatcgc cgagatttcc ccgcgcccgc ttctgctcat ccacggcgag
   937321 aacgcccatt cgcgatactt cagcgaaaca gcctttgccg ccgcagcgga gccaaaggag
   937381 ctgatgatca tcccgaacgc caaccatacc gatctctacg accgcatgga caagatcccg
   937441 ttcgaccgga tcgccaagtt cttcgggcag catctggcct aggtgaagcc gcgccattgg
   937501 accggcggtc agcggtcagc tctccgctgt cgccatcacg ctgcctgacc ctctgaatca
   937561 ggagacgccg gcccggtctg agggacttcg ccttcctgac caccggcctc ggcatcattc
   937621 ggcagaaccg cgttttacgt ggtcccgcca accctggaac aggcttgagg aaaagaagat
   937681 gaagtacatt gccgcaagca ttgctatctc ggctctcgcc gccaccgctg tggaggcgca
   937741 ggaagagcgg cgaaagatcg ctccaccggc cgtctatgac gtcgcgccgg gtctcggcca
   937801 cttcaccgac gatgttctgt tcggcgaagt ctgggaacga acagagctcc cgtctcgcga
   937861 ccggagcctc gtaacccttt cggcgatcgt ctcgacgggc aagacggcgc agattggcgc
   937921 ccatgtgagc cgggccctgg acaacggtgt gaagcctgga gagatcggcg aactcatcac
   937981 tcatcttgca ttctactccg gttggccaaa cgcgatctcc gccgtgacgg agacgaagaa
   938041 ggttttcgat gagcgccaga ttgcacccgt caagaacagc gaggcggcgc gcatagaatt
   938101 ggaagccgca gccgaggcgg ctcggagcga gacggtcagc accacggttg caccaacggc
   938161 ggcagcactg gccgacctta ccaaccgcgt gctcttcggc gatctgtggc agcgcccgga
   938221 tctgtcggcg cgcgaccgta gcttggtgac gatcgccgct ctgatcgcgg ttggtcagcc
   938281 ggaacaactg ccgtttcatg ccaaccgcgc gatggacagc ggcttgacgc cgtcagaagc
   938341 ttcagaagta ctggcgcatg tcgctttcta cgccggttgg ccgagagcca tgtccgccgt
   938401 gcccgttctc aagcaggttc tcaataacag gcaaggaact caggtgagcg cttcccaggc
   938461 agatctgaag attactccag ccggaattgg ttctgcgtca gctccggagg agtacttcac
   938521 aggtaccgtc cagatctcgg gccgttatca agccgacgct cccgcgcgca ttggcggggc
   938581 aaccgtctcc ttctccgccg gcgctcgcac ggcctggcac acacatcctc tcggccagac
   938641 cttgttcatc gtgagcgggc gcggcctggt tcagaaggaa ggtgaggcag ttcaggaagt
   938701 aggttcggga gacgtggtat ggatcccacc gctgatccgg cactggcatg gcgcctccag
   938761 caccgggccg atgacgcatt tcgcagtggc cgaggcgctc gatggaagct cagtcacgtg
   938821 gatggaaaag gtgtccgacg aggactacgg caagggtgtt cgagagtaga accggcaccg
   938881 ctagtggcgc gaactggctg cgcttcaggc ggcggcggag accttacgaa cggtctggat
   938941 ggaagtctgt cccgcagacg aaacggagcg acgaacgaat gctgaaaaca atgttgggct
   939001 ctgctgttat cgcactggga gtggttggac ccgtcatgcc tcaagaacgc atccgaattt
   939061 cttctgcatg gggcgaggtt accgcggacc tcgccgacaa cgaagctgcc aagtccctag
   939121 cgcagatgct gccactgacg atcgacatgt ccgaccattt ccgccaggaa aagacgggaa
   939181 atctgccctc cagcctgcct gagctgccac ggcagcgcga cttttccgtc ggcacgctcg
   939241 gcctgtggag ttccgatcac tttgtgatct attatcggac cggccgcgtc ccttcacccg
   939301 gcatcattgt tctcggcaag gttgcaggcg acgtctcgat cttcgatcgc ccgggatctg
   939361 ttaccgtaac gctggaggcg gtcgactgag acagtcgttc atcacgcgat ctctcctgac
   939421 ggtacagacg acgacggggc tacatagcat cgcgtgggcg ccgcgaccga gcccttcagc
   939481 gtagtcggca gagccaccga ccgccgataa cctctggccg ctggcgttcg atcccgaggg
   939541 accaacggac cggccgaaga agacatcgtc gtcagtgcaa ccgggaagcc cgggcaacct
   939601 ccccaagctg cattcaggat gctgattgat gaacaggagg gcttggacgt cgaggggtcg
   939661 cttcctttag atcgtcaatg acgtcatgct gttggaaaca gagcgtcctc tagggtcaag
   939721 ccaaaaaatg tggtaagcgc cagcgccaaa caacaacaac aacaggagtg caatggtgag
   939781 cgaaccgacc gtcgcagatg caataaaccg catttatgaa tcgctccaag cggacaatgc
   939841 cgacatcgac acgcatatcg cgactctcaa ggcagcgttg acgcgcgagg ggttgaaaga
   939901 ggccgtcttt gacccggcga ggctcgtgca gaacaaccgt tctggcagga agctcatgca
   939961 ggcctacttt cggcagcgcg gcgtaacggt caaatactcg gcttcgtgaa gccgtcgcat
   940021 gtcgtcagac gggccgtagt agacgattga cctgatcacc cagtattcgc cttcgaacgc
   940081 gaatcaagat gaggagagct ctatgccgaa agccgttgga atcggcggtc tgtttttcag
   940141 ggcggcgaac ccggctggcc tggccgaatg gtatcaaaag catctcggta ttgacgacct
   940201 gcacaagtcg gtatggcggc aggaggccgg gatgacgata tttggtcctt tctcgaagga
   940261 caccgactat ttcggtcgag cggaacaaca atggatggtc aatttccgcg ttgatgatct
   940321 cgatgggctg gtggccagcc tgacggcaag tggaatcgcg gtggaaacgc ggaatgaatg
   940381 gaactcggag gtaggtcgct ttgcccggat tcatgatccc gaaggcaatc cagtcgagct
   940441 gtgggagccg gcgcaggatt gatggcgaac gggtcctgca tgtgagcgaa tgaaagtttg
   940501 cgcttaactt cgccgcaccg gtgaccgcct taagcgctac gtcatcaaaa ctactggttg
   940561 acattttgac tgcaagccac tatctgacgt ttatcgatct ttttcttgct gagctttggt
   940621 taccgcgcga ctggcaccgc gcctgaacga acctttcctt taaaaaaatc gctatcacca
   940681 tccacgatgt caccaacatc gcggtcgatc accaatgcta cgaaagggtt catcatgacc
   940741 actggcacag ttaaatggtt taattctacc aagggcttcg gcttcatcga gccggataac
   940801 ggcggcgctg acgcgtttgt ccacatctcg gctgtcgaac gtgcaggcat gcgcgaaatt
   940861 gtcgaaggcc agaagctcag ctacgagctg gagcgcgaca ataagtcggg caagatgtcg
   940921 gcctgcaatc tccaggctgc ctaatatcgg tacctgctct ccttgaccac ggatgtactg
   940981 gcactgtcga gggcatgatt caactaaggc cgggcgtgat gcccggcttt tttttggccg
   941041 atggaacggc cgaccccgag aaagggaaac ctatggcaca gacgttcagt aagactcgtc
   941101 aacgggcgga aagcgctttc aacaaggtac aaagccagtt ctttgccaga ggccaggcag
   941161 tggaagagca agatttcgta gcgcaggccc gcgacgcgaa gacggctcgg ttgcgggagg
   941221 cccggctggc aaaagagtcg gatgaccgtg cgagagcaac ctcgactctc atcacgaggc
   941281 gggcaaaacc ggcgtgatcg ccggcttcac cacgcactca ggtaatgccc caatgcagga
   941341 aatcccgtgg cagacgatag gctcgaactt caggcaagca cgacggcatg gcagatcgca
   941401 atgcaggaaa tcctccgcat ggtcgtccgt gacctctatc aatctcatgg tgaagtcgcc
   941461 ttcacggcgc atataaagcg tctcgaagag ggtgcggtag acagcatcta cagcgacctc
   941521 aggctgagag gaacgaatga atggaccgaa acgctggtga aggagaaggc gaccaatatt
   941581 gtcacaaatc tcctgacctc cttcaccttc gagcaatctg accctcgacc ccggacggca
   941641 taaatctctg ccgatgtgcc acgaccacct tcaacaggac ggactcaccc tcacgcgcga
   941701 catgacgggt gacggcccac aaggagggtc atccgagctg ctgcgtgcag tctccatctc
   941761 cttctccgct ggcgctcgcg cggcgtggcg cacacatcct ctcaaccaga ccttgttcat
   941821 cgtgggcggg cgagaccatc tccgccagga aaaaaaggga aaactgacct ctggggcctg
   941881 cctgagctgc cacggcagcg cggtctttcc gccggcacgc tcggcctgtg gcgttccgat
   941941 tccattgtga tctatcatcg gacgagccgc gccccgtcgc ccggtaatcc ttgttctcgg
   942001 caacacttcg tacctgacaa gagtccagtc gcgcccggtt tgatctgcca cctcgtggcg
   942061 accccctgat tagagatcgt ccgcgctatc ggaatagtgc tacccaaatg ggtgggttaa
   942121 cacttcggca agcggcgcgt attctgtgca agacggcatc tacattccat gccgccatcc
   942181 tttttgggag gatgccatgg ctagactact cactgccatt ttcgtcgcgt tcggtatttg
   942241 cctcttttcg ctcgcctctg ccaaggctga cccgggcgac gaagtgaagg ccgcctattc
   942301 ggcgtgggac gcagcattca acaatgcgga cgcaaaagcc atcgcggcgt tctacacgga
   942361 cgacgctatt ttcttgcctg ccacccatga cgtgatcagg gggccttccg gagttgagaa
   942421 attctttggc ggcattttcg gtatgggcgt gacaggtcac aagcttgaac tgatcgaggc
   942481 acaaggcgag ggcaacctgc tgatcagcac ggcgaaatgg tcggccaagg gcaaagacgc
   942541 gaaaggcgct gaccagccat gggctggggt cgcaacccat atgttcgaga aacaggcaga
   942601 cggcggcctg aaactgagag tgcacacctt caattgagag agccacgcct cgcgggaaag
   942661 ccaagagggt agagttgacc tatcttgcaa atggccttcg gcttttttgg gggggccgac
   942721 ggcagccaga cgcgtcgtga cgggcggagc gatgatcgag ccggcgggtg gagggacgac
   942781 aacggggcac tagcagtaat caccgctgcc ccagcttcga accggtcgat cccggacaaa
   942841 gtgttaccta tgtctcagga ataaaccgta acctatgcgt ccagaatgga cctgagaaat
   942901 atggcgcgcc ggacaggatg aaacttgtct tcctcaaata actcggcaac ccgagctctt
   942961 atgttgtcgg aatgggtaaa agcataggcg tgagtttcga aatatgctcc ccgatccagg
   943021 gtattttgac tcgcactttg tagcttttat ttatgttcag gctcattgat tccccccgta
   943081 gcggccaata gtggtgattc ctcctggcga gagcaagcaa aggcttgcgc tattctcgtt
   943141 ttcatattct gacgatttgc ctgcttcgtc tggagccgtc cgtcaccctc accaacggaa
   943201 ggggtggcgg cggaaacagc gaagcacagg cctgctttgg tggtaggctc ccgagccctc
   943261 cttaaacctt gcgcgaagga tcgtgacccg cacgggcgga gactcgcgac cgaggcttcg
   943321 ggcaaagcct agagcccgac cgccccgcgg tcgcgccctg ccgcctaaga actataatgt
   943381 tcaaaattat cacgaagcgc ctttatgacc aaacaaatga acaaaacttg actttgcccc
   943441 cagcgccatg gcacagttgt acaaaattat ggacatgaga ctgccttacg tccatctgaa
   943501 tgaacaaaag gtaacaaaat tgccccgcac gagaagctat tcaagagtga cccgccaggc
   943561 actcaccatg ctcggaaagc tgatccgcat cggccgggcc gaacgcggcc tgacggcgca
   943621 ggaactggcc gaccgtgccg gcatcagccg cacgaccctt tccagcatcg aaaaaggcgc
   943681 gccggggccc gagatcggca tcgtcttcga agtcgcctca ctcgtcgggg tgcgtctgtt
   943741 cgactatgac gagcgcacgc tccagatgca aaatgcccgc ctcgacgaaa aactgaccct
   943801 gctgcccaag agcgtccggc acgcggtgaa ggaggttgat gatgacttct aaggcggatg
   943861 ccaccgaagc ctttgtctgg atttggctac cgggcgcaac agaaccggtt gtggcaggcc
   943921 gcctcttcca agagggcgag cgcctgctct ttaactacgg cgccagctac cgcggccgaa
   943981 agaccgccat tcctatctat gagcccgaac ttccccttca ggaaggcgcg attgcgccca
   944041 tcaacggctt gcagatggcg agctgcattc gtgacggatc gcccgatgcg tggggccgcc
   944101 gcgtgatcat caacaggctg acgggcaaga agcccgacgc tgacggcgtg ccggagatca
   944161 gcgagcttac ctacctgctc cattcaggct ccgaccggac gggcgccctc gattttcagg
   944221 catcggcgac agaatatgtc ccccgccgtg ccgcgcaggc atcgctcgac gaactcatgg
   944281 aagcggccgc cctcgtcgaa aagggcgtcc ctttgacccc ggcgctcgcc caggccctca
   944341 accacggcac ctcgatcggc ggcgcgcgcc ccaaggcgct gatcaacgac gacacaaaga
   944401 agttcatcgc taaattctcg gcgagcaacg acacctacag cgtcgtgaag gctgaattca
   944461 tcgcgatgag gctggcgagc gccagcgggc tcgacgtggc atccgtatcg ataacccgtg
   944521 ccgcgcataa ggacgtgctg ctgatagagc ggtttgaccg caggcacacc aaggagggct
   944581 ggacgcggca ggcgatggtc tcggcgctga cgatactggg ccttgatgag atgatggccc
   944641 gctatgcttc ttatgaggat ttggcggagc tgatccgcca tcgcttcact gcccccaagg
   944701 atacgctcaa ggagctctac gggcgtatct gcttcaacgt gctgtgcggc aacaccgacg
   944761 accatgcccg taaccacgcg gcattttggg acggcaagat gatgacactg acgcccgcct
   944821 atgacatctg cccgcaaagc cgcacgggca ccgaagccac acaggccatg ctgatcaagg
   944881 gcgagggtcg cgccagcacg ctggcgaatt gccttgcggc cgcgccggat taccacctga
   944941 aagaggcgga cgcaaccgcg ctgatcgaac accagatcac aaccatcgcc gaacaatggc
   945001 aggcggtctg cgcggaagcc gaactgaccc cggtcgaccg ccagtttttc gccggacgcc
   945061 agtttctcaa taactacgcc atagaggggc tcgaaggcca caaggcgctg cacgatgcgt
   945121 ttggtgccgc ccggaaggcg ctgatcgcaa gcggagacgc ctgaagatga gatcaccgct
   945181 tcgccgccct gatgcgcgag aacatcgcga acggccctgt gccgtttcgc cgtgcatatt
   945241 tacgcgccgt gatcgattag gttgaagttg atgacgggga gatcagaatt cacggtcgca
   945301 agagcgagct tgagcgcctt gtgatgacga agaacagcgt catcatggca gcagtgccca
   945361 gttttgtacg gaagtggcgc acccgacagg attcgaacct gtgacctttg gaatcggaat
   945421 ccaacactct atccagctga gctacgggtg catccgttgg cggcagggcc gccgaagcag
   945481 tctgtgaagc ggttcttagc ctagcttgcg cgccgcttca atggtgattg acggtttgcc
   945541 gcggaaattt gcgttcgact atggcgcaga gagcttgcgc cgagagaaat gccgcgtcct
   945601 tcgacgcggc atcggtggcg tttggcttgc cttcacgcca tctgcatggc gccgggaccg
   945661 gggatcgcct tggggggcac cttgcccatg atgatcatgc cgagcacctc gtccttcgtc
   945721 acgtcctcgg tgcgggcgtg gccgacgacc tggccgtttt tcatcacgga gacacggtcg
   945781 gcaaggtcga agacatcgtg gatgtcgtgg ctgatcagga agatgccgat gccctcgcgc
   945841 ttcaattgtt tgatgagttc gccgacctgt gctgtctcct ggggtccgag tgccgcggtc
   945901 ggttcgtcca tgatcaggat gcgggcgtcg aagaggatgg cgcgggcgat cgcaaccgat
   945961 tgccgctggc cgccggaaag cgctttcacc ggctccttga agcgctggaa gttgggattg
   946021 agccgtccca tcacctcgcg tgccttggct tccattgcca catcgtccag cgtgccccag
   946081 ggggtgcgca gttcgcggcc gagatagagg ttggctgcgg cgtcgacatt gtcggcgacc
   946141 gcgagtgtct ggtagatcgt ctcgatgccg tatttcttgg cgtctcgcgg attgccgatc
   946201 tcggcaggtt cgccgttgat caggatctcg ccggcatcgc gcctgtaggc gccggagaga
   946261 atcttgatca gcgtcgattt tccggcgccg ttatggccga ggagggcgac gacctcgccg
   946321 gggtagagat cgacggaagc attgtccacc gcatggatgc cgccgaagga gatggaaata
   946381 ttcttcattt ccaccagcgg agtgcgttgt tcagtcatgt tcgaactcct aattattttg
   946441 cgcgggcgcg gtagacggtg tcgagccaga cggcggtgac gagcacgaca ccgacgacga
   946501 tccgctggaa gggcgtgtcg atcccgagaa gcaccatgcc tgactgcagc gattgcatga
   946561 cgagggcgcc gatcatcgcc ccggcgatgg tgccgacgcc gccggcgagc gaagtgccgc
   946621 cgatgactgc ggcagcgatc gtgtagagct cgtcgagttc gccctgtgca ttggtcgctg
   946681 cgttgaggcg cgcggtcgag atggcggcag cgatcgcgca gagcacgccc atcagcatga
   946741 agatcttgac ggtgacccag cgcgtcttga ttccggcgag ctcggccgct tcgggattgc
   946801 cgccaagtgc gaagacgtag cgaccgaagc ggaggcgggt cgctatgaag gtcatgacga
   946861 tgcccacgac gatcgcgacc agtacgggaa cggcgatgcc gtgcgggatc tgcaggccgc
   946921 cgtccggcca ggcaatgctg ttcgcatcgg catatctgcg ggcgatattg atgggccagt
   946981 aataatgatt tgcgacggag accgcgccaa gcaccagggc acagccaagg attgtcagga
   947041 agtattcggc ccagaccggg cgcaagggaa acccgaagcg tttgcgttgc ctgcgcgaat
   947101 tgaggacggc gccgatgatg gcgatacagg cgagaacgcc aacgacccag ctcgccgtgg
   947161 cgccgatcga accttgggtg ccgccgccca tgagacggaa ggtggtgtcc atcggcgcga
   947221 ccgtctgtcc gctcgtcaca aaccaggtgg cgccgcgcca gacgagcagg ccgccgagcg
   947281 tcacaatgaa ggagggaacg ttgaggaagg cgatgatcga tccgtgaagc gcgccgatgg
   947341 cggcgcccac cgcgatgccg caggcaagcg taattgccca gatggcggga tgaccgagcc
   947401 cgagatattg cggcaggacc tgcgcctgca gcacgcccat gatcatgccg caaaagccga
   947461 gcacggagcc gacggaaagg tcgatgttgc gggtcacgat gacgagcacc ataccggtgg
   947521 ccataacggc gacggatgag gtctggacgg tcaggttcca aaggttgcgc ggcgtgagga
   947581 acaatcctcc cgtcatcacc tggaaaccga gccagatgat gatcagcgcg ccgaccatgc
   947641 cgagaagccg ggtgtcgatt tcagtggcgc ggaagaatcg cttcaccagg ttttcgttcg
   947701 cctttcgggc gcggctcgtt tgcgtaccct gtgtctggtt ggcttgtgtg atgtcggcca
   947761 tggacatgcc ttcccccacc tatgtgttga tgtcgtcgcg ccgagcggca gcgagagcgg
   947821 tcagcacgtc cggtcatggg ccggacttcc gtcgactctc ggattgcttc ggatgcgatc
   947881 ttgccggtcg gcctcgcatc ttgcgagagc gccgcaacga tttgcgttgc ggcgctctcg
   947941 aagactattg atcggtcccg tgcttgcggc ttacttgcac gcagccacgt cgtccttggc
   948001 gccctggcag gtctcttcct tggcaatcca gccggcatcg atgacgacat tgagattgtc
   948061 cctggtgatc gccagcggtg ccaggaaaac ggatttcatg gccacgccct tggggccgcc
   948121 gtcaaaggtc tggacgcctt cgatttcatc catggtcttg ccggcggcaa gcgccgcggc
   948181 aatctctgcc gctttcttac cgagttcgcg ggagtccttc cacaccgaaa ccgtctgcgt
   948241 gccgcgagcg acgcggttca gcgctgcctt gtcggcatct tggccggaca caggaaccga
   948301 accggcaagg ccctgggcgt cgagtgccgc gatcgcgccg ccggcggtcc cgtcgttcga
   948361 ggccacgatc gcatcgacct tgttgtcgtt agccgtcagg aactgttcca tgttcttctg
   948421 ggcgttttcc ggcttccagc catcggtata ggcctcgccg acattcttga tcttgcccgc
   948481 atcgatggca tccttcagga cttccatctg tcctgagaaa aggaagtcgg cgttcggatc
   948541 ggcggaggag cccttgatga agacgtagtt gccttccggc ttctgcttga acacctcgct
   948601 cgcttgcagg cggccgactt ccttgttgtc aaaggtgatg tagaaggcgg ccgggttttc
   948661 gatcaggcgg tcatagccga cgaccgggat cccctcggca gcggccttct cgatagccgg
   948721 accgatcgca tcggagtcct gcgcaagcac gatcagtgcg ttggcgccct gggcgattag
   948781 cgattcgatg tcggtgagct gctttgctgc tgaagactgt gcatcggccg aaatgtattt
   948841 gtcgcccgag gcttccagcg cggtcttgat ggcggcctca tcggtcttcc agcgctcctc
   948901 ctggaagttt gaccaggaaa cgccgatgac gagatccttg gcgatcgccg cggaatgcat
   948961 ggacgctatg atggcagccc cggccatcag tttcaaaatg gatttcatct taccctcccg
   949021 ttttgcccgg ccgcgcgtag gaacctccca tacgcatccc cgacgagcct tgatccgctg
   949081 ccgtaaacct ctccggtgct gcgcccggcg ttttttctcg acagtcgaga aaatagatgt
   949141 cagagttttc ccaggctgtc aacaagggct taccatcgca ggggtgatgg ccgcaccgcc
   949201 ttgaaaatcc tgcggcaaag atgggtgtgc cttgtcttgc cggcccgcag atgcttggga
   949261 ggagcatgtc ttcggaaaag tcgcaccgtc actgcatgtc gtctttcaac caacccggtc
   949321 acaggaaaaa catgcagcag cctaagaagt ttcggcgacc ggagcgcgtc ttgtcagatg
   949381 cgcggcgctg ggtgagccga tgatgctgac caagtccagc accgaactcg tgcgtcagca
   949441 gaacagcgcg ctggtgctcg cggcgcttcg gcggaagggc tcgctttccc acacggagat
   949501 tgcggcacag accgggcttg cctcggccac gatctccgtt atcacggccg agctggagcg
   949561 cgccgggatc atcgccaaaa tcgagaggca tgtgcagggc ggtcgcggcc ggccgcgggt
   949621 tctcttcgag ccgagacgcg attgcggtca cgtgatcgtc gtgcggatct cttccgacgt
   949681 ggtgcaatac tcgcttgctg attatggcgg cattctgctc gatcgtttcg aggaggtgcg
   949741 cggtgacctc ggcgggacag ctgccttcgg ggaggtcctt gcagcggcac ttgaacggtt
   949801 gctcctccgc tcgaatatat cgaaggacga ggtgcttgcc atctcgatca gcagcaaggg
   949861 gctcgtggcc gccgatggcg cgcgacttat ctggtccccc gtcttcggcg gcgagcaact
   949921 cgatttcgtg aagctgctgc gtcctgattg gcgcgccagg atcatgctca gcaatgagtc
   949981 gctcctcgtg gcgcacgcgc ttgccgtaaa ggaagaggaa aaacaggtcg gtttccgcgc
   950041 gctcgccgcc gtgtcgctcg gacacagcat cggcctcggc cttgcccgaa gtggcagctc
   950101 cggtgagctc gatgtctcgg ctccgaactt cggccatatg ctgcatcagg atgccgccgg
   950161 gctctgccgc tgcggcagtt ttggctgcgt cgaggccgcc gccggtttct acgggattct
   950221 gcgcacggcc ttcgaggtgc cctccaatac catcccagcc aagttcgtgc cgctttcgga
   950281 gatggacaag atcgccgcgc gtgcacggca aggacatcgg atggccgcct atgccttccg
   950341 acaggccggc gttgcgctcg gcaacggaat ttcccggatg ctcagtctct acgagccgat
   950401 gccgatcttc gtgactggac cgggcacgcg ctatttcgat ctcctgcaga agggactgga
   950461 ggagggcatg gcacattcgc tgcaggtgcg ccttgagggc atgccgcaga tatcggtggt
   950521 tattgacgaa caacggctcg ttctggatgg tcatctcgac cgggcgctag gggcaatcga
   950581 cggcgacatt gccgcctcgg gccacccatg agcccacgcc cgcccccatg gtcatcgtga
   950641 ccatgcggcc tggcaagaag atttgctgcg ccttaaagag gcatagtggc tacgccgaaa
   950701 aaggccggga ggtccccggc catctctttt agaacaaccg gaccgtcaag cgacgctgac
   950761 ctgacgcttt tccgcgaccg aacggacggc cgcatcggcg agcgcgagcg ctgcaagtcc
   950821 gtcctctccg gacggtgcga tctcggcgcc cttttctatt gcggcgacga agctttcgat
   950881 ctcgttcgca taggcttccg tgtagcgcgt catgaagaaa tcgtgcagcg gcgggcgcgt
   950941 gtagccgtcg acggtcgcga tctcgatcga cacgggacgc tgattttccg cggcgactgc
   951001 gcccttggag ccgtggacct cgatacgctg gtcgtaaccg taggtggcac ggcgtgaatt
   951061 cgagatgatc gcctgcttgc cggaagccgt ctgaaggatg acggagacgc tgtcatagtc
   951121 gccggcttcg ccgattgcca tgtcgacgag tacggccgca gtcgcggtga cggaaaccgg
   951181 ctcctcgcca aggaggaaac gtgccatgtc gaaatcatgg atcgtcatgt cgcggaaaat
   951241 tccgcccgag cgcttgatat agtcgacggg cggcgcccct ggatcgcgcg aggtgatcgt
   951301 caccatctcg acttcaccga tccgtccgtc gtcgatcgcc ttgcgtacgg ccatgaaatg
   951361 cggatcgaag cgacggttga agccgaccat cagcttggcc ttggtctcgg acacgacctt
   951421 gaggcaggcc ctgacgcgtt cgacatcgag atcaacaggc ttttcgcaga aaatagcctt
   951481 tccggcgcgc gcgaagcgct cgatcaggtc ggcatgggtg tcggtcggcg tgcagatcac
   951541 cacggcgtcg atgtcgcttc ccgcctggat agcatcgatc gtacggactt cgcagccata
   951601 ggcgccggcg atcgcttcag cggcggcggg aaaggcgtca gcaacggcga caaggcgcgc
   951661 atcggcattg gcgctgacag ccttcgcatg aaccttgccg atgcgtccgg cgccgagaag
   951721 accaaatctc actgtcatct gtattgtcct tgaattccgg tgtgcgaccg ggttggcgca
   951781 cgatgatcga cgctcatcgc gcaaaggcgt cgcggggcat ccgcgcatga actggaatga
   951841 aacggccaat tactgcgtgt gcggaatgtt tattccaaca agcttggcgc cgtcaagcct
   951901 ccaccgcgaa cggttccacc ggtcgggccc acgtcctcgc cttggtctgt tctctgggca
   951961 gttggatttg ctctcgttgt ggaaatatgc agtagatgaa tcggaattaa gtctcccaaa
   952021 ggaaccagga tgatcaaatt tatcgatccg gatcacccct tctatcgtcc cttgtggatc
   952081 cggctgctga tcatcgtgtt ctgcgcggta tggacggcgg tggaattcta cggcggacag
   952141 acgatgtggg gaacgatctt tctcgtggta accgcctatg ccggcgcgac ccttcttgtt
   952201 ttttaccgac cgaaggagga ggagcagggc aagagcggcg ctaccggcaa gacgaatgag
   952261 ggcacgagtg acggcacgaa ctgacgtcta tttcggcatg ctcggctttt tgatccgcct
   952321 gaaagcctcg tcgatcagca tgttggcgag cttcatgcgc aaagtcgcat tgagtcgcgc
   952381 ttccgctggc aacctgtcgg gatggttcgc tgcggcgaaa cgcctgcgcc tggccgcaag
   952441 cgtcagcgcg gtctccgctt cgccgagcgc cagctcggag gcgacttcag caaggctgat
   952501 gcgctttaga aaatcgggta ttgcaaaggg cgcggggctc tcggtcggcg tcagctcaca
   952561 ataggcctgc tgcaccgtgg tataagtggc cgcggtgccc gacgaggtct ccgggacgaa
   952621 tcccgaagtg gtaccgatga cggtaccagg cccgccagtt gcctctccca gcatctccgc
   952681 gtcctgctcg tccctgagcc gctgcagaac cgactggaaa aacgagattc cgaacatcat
   952741 gtctcctgaa acaggcgctg aatgtccgag catggcgtca gaatattacg cgaaactgat
   952801 catgccctgc tttgcttcag aatgaggtcg taaagcagct tcgcgctggg cgggagcgcc
   952861 cgtccctcgg cggttatcag cccgtagggc ttgatgcgga tcggaaaccc ggtccgcaat
   952921 atcttgattt caccggcttc ggtgccgttg ccggccacca gcctggcgac atccagcgca
   952981 acgggagcga ttgcgttggt gtttcgcacg atggacagcg tcaggatggt cgacgaggtg
   953041 ttgatgaccg ttgccggaag tcgcacgccg gcggaaccga aactgtcctc tacggcgcgg
   953101 cgaagtagcg tgccgggcgg ctggaagacc cagtcatagc ccgggagatc gtcggcactg
   953161 accgacgcct tctccagaag agggtgaccc tcccgaacga tcaggcagac ttcctcgaag
   953221 cccatctcga tcaggttgaa cagtcgcgga ttgaggtcgt ccggaattcg tccgatgatg
   953281 aaatcgtgac gagccgcgag aagctcgcgc gtcagcacat tgctgttgtc gatctgtacg
   953341 ttgatctcga tgcctggata ggccgtcgac acctgccgga tcgccgggac tgcaagattg
   953401 agggccgggc cggtgacgga gcccagtgaa accgatccgc cgctgccggt tttcaattca
   953461 ttgatctcgc gcgcggcctc gcgcaactca aggaaaatgg tgcgggcgcg gcgtgccagc
   953521 gcttcgccgt agctggtcag ctcgacgccg cgcgccaccc gctcgcagat cggcgccttg
   953581 gcgatcgcct cgatctcggc gagcatgcgc gaggctgccg gttgcgagat cccaagcgaa
   953641 tcggctgcgg cgctgatgcg ccggtggtcg tcgatcgcca ggacgagccg cagatggttg
   953701 atcttcaacc ccgatcggaa aagtcctgtt tcgaggagtt ctcccgcggg cccggacgca
   953761 ttcggcctgc cttcgagcat tccaatcggt tccgttttca agaatttcaa aaatcacact
   953821 ctttcaaggt ggtatatcaa ttttggtatg catgcaaagc gatattgtat ttgacagtta
   953881 tggcaattga ttccagtttc gaaccatatg cgccagtgca tgcgggagta tgtgagacgg
   953941 ggagggcttc cttcatcttg aagcaccgcc ggggatgatc ctccgcgacg gtggtcgcag
   954001 cgcatagacg gggggccctg cgcctgccgg ttcaacactc agggagagat ctgatgaaat
   954061 tctttacttc gcttctcgca gctgcggcga tgacggtcgc cggcttcgct gcgccggcag
   954121 tcgcccagga caagggcatg gtcggcatct ccatgccgac aaagacgtcg acgcgctgga
   954181 tttccgacgg cgaaaccatg gagaagctgt tcaaggatgc aggctatacg ccggacctgc
   954241 aattcgccga cgacgatatt ccgaaccagc tcgcgcagat cgagaacatg gtgaccaagg
   954301 gcgcgaaggt cctcgtcatc ggcgccatcg acggcacgac gctctccgac attctgcaga
   954361 aggccgccga cgccggcgtc aaggtcatcg cctatgatcg cctgatccgc gattccggca
   954421 atgtcgacta ctatgccacc ttcgacaact tccaggttgg cgtcctgcag gcgacctcgc
   954481 tcgtcgaggg tctgaagctc gacagcgcga ccgagccgaa gaacatcgaa cttttcggcg
   954541 gctcgccgga cgacaacaac gccttcttct tttacgacgg tgcaatgtcc gttctgcagc
   954601 ctctgattga cagcggcaag cttgtcgtca agtccggcca gatgggcatg gaccaggtcg
   954661 gtacgctgcg ctgggacggt gctgtggctc aggcccgcat ggaaaacctg ctgtcgtcgg
   954721 cctataccga tgcgaaggtc gacggcgttc tgtcgcccta tgacggactg tcgatcggca
   954781 tcatctctgc tctcaagggc gtcggttacg gctccggcga catgccgatg ccgatcgtca
   954841 ccggtcagga cgccgagctg ccttcggtca agtccatcct tgcgggcgaa caacattcca
   954901 cggtcttcaa ggacacccgt gaactcgcca aggtcacggt caacatggtc aacgcgatca
   954961 tggacggcaa ggagccggaa gttaacgaca ccaagacgta tgaaaacgga gtcaaggtcg
   955021 ttccgtccta tctgctgaag cccgtttccg tagacaagtc gaacgccaag gacgttcttg
   955081 tcggctccgg ctactacacg gaagatcagc tcaacaactg atgcggcgaa ccgagagggt
   955141 gcgcgacagg ctcgcgcgcc ctcttaatcc acgcggcatg cgtctctttg caatgtcgct
   955201 gtagcacttt gacccgccgc gtggttttat ttcgtatcgg agccggtcga aagaaccgcg
   955261 cagcacggga gagcgcctgc attctctctg agactgcagc tggaatggct gagtatggac
   955321 aatatcattc ttgaaatgcg gggcattacg aagacgtttc cgggcgtcaa ggccctggac
   955381 aacgtctcgt tcaaggtccg cgaaggcgaa atccacgcgc ttgtcggaga aaatggcgcc
   955441 ggcaagtcga ccttgatgaa ggtgttgagc ggcgtctatc cggccgggac ctacgagggc
   955501 gaaatccatt atgacggaaa acttcgccag ttcagcacga tttcggacag cgaagatctc
   955561 ggcatcatca tcatccacca ggagctggcg ctcgttcccc tgctttcgat cgccgagaac
   955621 atctttctcg gcaacgaggt ggccgaaaag ggcataatcc attggccgca gactttcgca
   955681 cgcacgcagg agctcctgaa gaaagttgga ctgaacgagt cgccggcgac gctgatcacc
   955741 gacatcggcg tcggcaagca gcagctggtg gaaattgcca aggcgctttc caaaaaagtg
   955801 cgcctgctta tcctcgacga acctaccgca tccctcaacg aaaacgattc cgacgcgctt
   955861 ttgaagctgc tcatggaatt ccgcagccag ggcatgacgt cgatcatcat ttctcataag
   955921 ctcaacgaga ttaagaaggt tgccgaccag atcaccatcc tgcgcgatgg cggaacggtg
   955981 gagacgctcg actgtcacaa ggaggaggtc ggcgaggacc ggatcatcaa cggcatggtc
   956041 ggccgcgcca tggaagaccg ctacccgccg cgcgagccga agatcggcga cacgctgctc
   956101 gaggtgaaga actggaacgt ctaccatcag catcaccgcg accggcagtt tctgcacgat
   956161 gtcagcttca aggttcgcgc cggtgaggtc gtaggcatcg ccggactgat gggcgccggc
   956221 cgaaccgaga cggcgatgag catcttcggc cggtcctggg gacacaagat caccggtgac
   956281 gtgacgatgc gcggcaagcc cgtggacgtg agcacgatcc cgaaggcgat caaggcgggc
   956341 cttgcctatg tgacggaaga ccgcaaacag cttggcctcg tgctgatcaa caacatcatg
   956401 cacaacacca cgctttccaa tctcggtgcg gtttcctcga acggcgtcat cgacgagcga
   956461 aaggaggctc gggtcgcctc ggactatcgc tccaagctgc gcatccgttc gcactctatc
   956521 tatcaggagg cggtcaacct gtcgggcggc aaccaacaaa aggtcgtcct gtccaagtgg
   956581 ctgttcacca atcccgaagt gctcatactc gacgagccga cccgcggtat cgatatcggc
   956641 gcgaaatatg agatctacac catcatcaac caactcgcag ccgagggcaa aggcatcctc
   956701 atgatttcgt cggagatgcc ggaactgctc ggaacctgcg atcgcatcta tgtcatgaac
   956761 gagggccgca tcgtggcgga gctttccaag gaggaagcaa gccaggaatc gatcatgcgc
   956821 gccatcatgc gttcagggga gaaacactaa tggtcgccga tacgagcacc caaaccacca
   956881 aaccgtctat cggtgactac ctcaggaaca atattcgcga atacggcctg ctggtcgcgc
   956941 tcgtgatcat catgctgttc ttccagttcg tcaccaacgg cgtcttgttc aggccggtca
   957001 acatcaccaa tctggtgctg cagaattcat tcatcgtgat catggccctg gggatgcttc
   957061 tgatcatcgt cgcagggcat atcgatcttt cggtcggctc catcgtcgct ttcatcggcg
   957121 cgatctcggc cattatgctg gtcaaatggg ggctgccggc ctttgtcgtc gtacctgcct
   957181 gtctcgtcgt tggcggcact atgggagctg cgcagggata ttgggttgcc taccagaaga
   957241 tcccggcctt tatcgtgacg ctggcgggca tgctggtctt ccggggtatg acctatgtgg
   957301 tcctcggcgg gcgccccatc ggccccttcc cgaaggagtt ccagatactc tccacgggtt
   957361 tcgttccgga ttttctctac ttcctcaatc cgagccccga cctgatcaag aacatggtgg
   957421 cgctcgtggc cgtgctgctg ctggtcggct atgcgattta tgcgggcctg cgcaatcgcc
   957481 ggatcaacga acagcatggt agcgagaacg agcccttcat cttcttcgcc atccagatgg
   957541 ccgtgatcgg cgtcgttgcg ctcttcatcg gctttcagct ttcgacatat cgcggcctgc
   957601 ccaacgttct catcgtcatg ggcgtgctga tcgcccttta taccttcgtc acgtcccgct
   957661 cgacggttgg ccgacggatc tacgcaatgg gcggaaacga gaaggctgcc aagctctccg
   957721 gcatcaatac cgagcggttg accttctacg ccttcgtgaa catgggcgcg cttgctgcgc
   957781 ttgccggcat gatcattacg gcgcgcctga attcggcaac cccgaaggcc ggcgtcggct
   957841 tcgaactcga cgtgatcgcc gcctgtttca tcggcggcgc ttccgcctcg ggcggcgtgg
   957901 gcaagatcac cggcgcggtg atcggcgctc tcatcatggg cgtcatgaac aacggcatgt
   957961 cgatcatggg catcggcatc gattaccagc agttgatcaa gggcctcgtg ctgctcgcag
   958021 ccgtgttctt tgacgtctac aacaagaaca agggcaaggg ctgatcggtt ccggtcagcg
   958081 ctcgatgatc gcaacagaga gaggcggcac tgccgcagca actgggtggc gtgagccaat
   958141 cccgaggcgg agcgttgccc tttccgggag gaaaggcgtc gcgaggccaa gtcatcagga
   958201 aggatagaag gtgctgattt ctcaggtcag gaaagaagac ggttcgatta tcgtcgcggt
   958261 gcgggtcccg ggcgagacgg cgcatgccgt caggggagcc gaaagcgtct atgctcttgc
   958321 gatggaggct gccaacaccg gcaggagtct taaggatatc atcgacgcca ggggacttga
   958381 cgaaacgatc gacctccagg aggcatattc tcaggggcgg ctgctttcgc cgatcaccca
   958441 tcccgatccc gcccatctcc atatgacggg taccgggctg acgcatctcg gctccgccgc
   958501 aacgcgcgat gcgatgcaca agaaggccac ggaagccgcc gaggaaacgc tgaccgactc
   958561 gatgaagatg ttccgcatgg ggctcgaggg cggcaagccg attccgggcg agcgcggcgt
   958621 gcagcctgaa tggttctaca agggcaatgg cacatcggct gtagcgccgg gggagccgct
   958681 ggtttcacca tcctttgcgg aagatggggg cgaggagcct gaaatggccg gcatctatgt
   958741 gatctccgac aaaggtgtcc cttaccgcct cggcttcgcc gttgccaacg agttctccga
   958801 ccacaagacc gaacgggtca actatctgtg gctggcgcat tccaagctcc ggcaggcgag
   958861 tttcggcccg gaaatccgca taggcgcggc tccagaggat attcgcggcg tttcgcgtat
   958921 ccatcgcggc ggcgaggtcc tgtgggaaaa gccgttcctt tccggtgagg cgaacatgtc
   958981 gcacagcttt gccaatcttg aatatcatca tttcaagtac ggcatattcc gtgcaccggg
   959041 cgatgtgcat gttcacatgt tcggcacggc aacgctctcc ttcggcgacg gcatccgcac
   959101 ggaagagggg gacgtattcg agatcgaagc caaggaattc ggcctgcccc tgcgcaatcc
   959161 cctggcaatc gcggcagagg aagaggtcgc tgtccatcag ctctgaccta tctcccatgg
   959221 caggcgcgtg ccgtaacccg gccgtcgcgc ttgcggaaga agacaaggaa gcggaagcca
   959281 tgacacttca ccagaacctg atcgccggcg aatgggtcgg cgaagacggc gttgcgaacg
   959341 tcaacccgtc gaacaccaat gacgtcgtcg gagattatgc ccgcgccagc gccgaagacg
   959401 cgaaagccgc gattgcggcg gccaaggctg cctttcccac ctggtcgcgc tccggcatcc
   959461 tcgagcgcca tgcgatcctg aagaaaaccg ccgacgaaat cctcgcccgc aaggacgagc
   959521 tgggacggct gctgtcgcgt gaggagggca agaccctcgc cgaggggatc ggcgaaacgg
   959581 tccgggccgg tcagatcttc gaattcttcg ccggcgaaac tttgcgcctc gctggcgagg
   959641 tcgtcccatc ggtcaggccg ggcatcggcg tcgagatcac ccgcgagccg gtcggcgtcg
   959701 ttggcatcat cacgccctgg aactttccca tcgccattcc cgcctggaag gtcgctccgg
   959761 cgctctgcta cggcaatacc gtcgtcttca agccggcgga actggtaccg ggctgttcat
   959821 gggcgatcgt cgatatcctc catcgtgcgg gcctgccaaa gggcgtactg aacctcgtca
   959881 tgggcaaggg ttcggtcgta ggccaggcaa tgctcgacag cccggacgtt caggcgataa
   959941 ccttcactgg ctcgaccgca accggaaaac gggtcgcagt cgcctcggtc gaacataacc
   960001 gcaaatacca gttggagatg ggaggtaaga acccgttcgt cgttctcgac gacgccgatc
   960061 tttccgttgc cgtcgaagcg gcagtcaatt ccgccttttt ctcgaccggt cagcgttgca
   960121 ccgcctcctc gcggatcatc gtcaccgagg gcatccatga ccggttcgtc gccgccatgg
   960181 gcgagcggat caagggtctc gtcgtcgacg acgcgctgaa ggccggcacc catatcggac
   960241 cggtggtcga tcagagccag ctcaatcagg acaccgacta catcgccatc ggcaagaagg
   960301 agggcgcgaa gctcgccttc ggcggtgaac tggtctcgcg tgacacgccc ggcttctatc
   960361 tgcagccggc gctgttcacc gaggcgacga acgatatgcg tatctcccgc gaggaaatct
   960421 tcggacctgt cgcggccgtc atccgcgtca gggattacga tgaagcgctg gccgtcgcca
   960481 atgacacgcc cttcggtctg tcttcgggta tcgccaccac cagcttgaaa cacgcgacgc
   960541 acttcaagcg caatgccgag gccggcatgg tgatggtcaa cctgcccacg gcgggtgtcg
   960601 acttccacgt gccgttcggc ggccgcaagg cttcctccta cggtcctcgc gagcagggca
   960661 aatacgccgc tgaattctac accaatgtca aaaccgccta cacgctggct tgaacagaaa
   960721 agagcgggat gcaggcggaa agccgcgaaa gacatcctca tcccgctcgc aagccgacgt
   960781 tatttccgcc cgcgcctggg ccataaggaa ggaagaaatg aagaagaaag ctgagtggcc
   960841 gcgcaagctc cgttcgcagg attggttcgg cggtactggc aagaatgcca tcatgcatcg
   960901 ctcctggatg aaaaatcagg ggcttcccgc tgacactttt gacgggcggc cgatcatcgg
   960961 catctgcaat acctggtccg agctcacgcc gtgcaacgcg catcttcgcg accttgcaga
   961021 gcgcgtgaag cgcggggtct acgaggcggg gggcttcccg gtggaattcc ccgtcttttc
   961081 gaccggggaa agcacacttc gcccgacggc gatgatgttc cgcaacctcg cggccatgga
   961141 tgtcgaggaa tcgattcgcg gcaatccgat cgacggcgtc gtgctgctcg gcggctgcga
   961201 caagacgacc cccagcctcc tgatgggagc ggccagcgtc gacattccgg cgatcgtcgt
   961261 ttccggcggt cccatgctca acggaaagtg gcgcggcaag gatgtcggtt cgggcaccgc
   961321 gatctggcaa ttctcggaaa tggtcaaatc cggtgagatg acgctggagg agttcatgga
   961381 cgccgagcag ggcatggccc gttccgcggg aagctgtatg accatgggta cggcctcgac
   961441 catggcgtcg atggccgaag cgctcggcat gaccctttcg ggcaacgccg ccattccggc
   961501 ggtggatgcg cgccgtcggg ttatttcgca gcttaccgga cgccgcatcg tcgagatggt
   961561 caaggaggat ctgaagccct ccgacatact gaccaaggag gcattcgaga acgctatccg
   961621 cgtcaacggc gccgtcggcg gctccaccaa tgcggtgctg catcttctcg cgctggcagg
   961681 tcgcgtcggc gttgatctat cgctcgacga ctgggacagg ctcggccgcg acgtgcccac
   961741 catcgtcaac ctccagccct ccggcaagta tctgatggag gaattctatt atgccggcgg
   961801 cctgccggtc gtgatcaagg cggtcgcgga gatgggcctg ctgcacaatg atgccatcac
   961861 cgtcagcggc gacacgatct ggaacgacgt caagggcgtg gtcaactaca acgacgacgt
   961921 gatcctgccg cgggaaaggg cgctcacgaa atcgggtggt atcgcagtgc tgcgcggcaa
   961981 tctcgcgccg cgcggcgccg tcctgaagcc atcagctgcc tcgccgaacc tgatgcagca
   962041 caagggccgc gcggtcgttt tcgagagcat cgaggattat cacgcacgca tcaaccgtga
   962101 ggacctcgac atcgacgaga cctgcatcat ggtgctgaaa tattgcggtc ccaaaggcta
   962161 tcccggcatg gccgaggtcg gcaatatggg tctgccgccc aaggttctga aaaagggagt
   962221 gacggacatg atccgcattt cggatgcgcg tatgtcgggc acggcctacg gtacggtcat
   962281 actccatacc gcgccggaag cggcggaagg cggtcccttg gcgctcgtgg agaacggcga
   962341 tctgatcgag gtcgacatcc cgaaccgcac gctgcatctc catgtttccg acgaggaact
   962401 tgcgcgtcgc cgcgcggcct gggtgtcgcc ggtcaagccg ctgagcggcg gctatggcag
   962461 cctctatatg aagacggtca tgcaggccga cgccggcgcc gatctggact tccttgtcgg
   962521 cccacgtggc gatcgcattc cgatggatcg agacagccat tgataccgta gggcgcagcg
   962581 cgtcctggca gacgcgggaa gggcgccttg ccactctgat ttgctgcgcg gcggtgtgaa
   962641 aaccaccgcg cagtttcctg catagggcgc tattccggcc ggcttgccgg taggtaagtt
   962701 gttactgatt tattcgcgaa acttattcgc gtgttcggac ttatcctcga tcgggcaatc
   962761 gcatcggacc caaggaggaa atgtgcatgc cgaataaagc ccttgttctg tctgtcggtc
   962821 tgttgaccag cctggccttt tccccgtctt ttgcccagag cgtcggcggg aacggaggat
   962881 tgaatgttgg agtctcgttg ggaggctcga acggcgtaaa cgccaatgtc ggcgcttccc
   962941 ttggcggctc cagaggtgtc aaagccgacg ccgacgcttc cgtcggagga tcgcgcgggg
   963001 tgaacacctc ggcgactgca tccgttggcg gtagccacgg tgtaaacgcc gatgtcgatg
   963061 caagcgtcgg aggcagccgc ggcctcaaca gcaatgtcag tgcaaatgtc ggcggcagca
   963121 acggcatcga cgccgatgcg aacgtctcgc tcggaggccg tcgcggtctc aacgctaacg
   963181 tttctgctaa cgccggcggc ggcagcggtg cggggctggg cgttgggctc ggtctcggcg
   963241 gcagctctgc cggcggggtc ggacccggca gtggcggtgg tgcaccaggt gccagtggcg
   963301 gggccggaat cggggctccc ggccaaagcg cggtcgcagc tttcaatgcc atgtccccca
   963361 gcgagcgccg catggtgctg aagcgttgcc gtgatgtcgt caacggtggc tatgacaggg
   963421 gtttggtcgc gctgtgtcga ctgctgcagt cgactgcatc gcgctaaggt ccgcgccaga
   963481 ttttgccctc tcatccgctt taacccgaga accaaccctc ttcccgttct agcggggaga
   963541 ggggtctccg gcaggccgat gagggcgcgt catcggcacg gcagatgagc gaccggctcc
   963601 gatgctaatc ctaacattga acctggcgct gcgcctgctt ttcgacggta agggccacct
   963661 tcagtgtctc cgcgccgaaa ccgtgcacca gccccgagac cggcgctgcg tcgcgatagc
   963721 agaggcccga ggcgatgcgg acatagcggt cgtccgggca gaccttgttg gcggcatcga
   963781 agccgaccca tccgaggccg gcaatgtgta tgtcggccca ggcgtgactt gccgtctgct
   963841 ccgtacggtc ctccatcatt agatagccgg agacgtaacg agccggcagc cccagcgtgc
   963901 gggcggctga gatcagaaca tgggcatggt cctgacatac gcccttgcca cgctccaggg
   963961 cttcttccgc cgtggtcccg acctgcgtct cgcccggctc atatctgacc gcagcatgga
   964021 caagtgccat cagggaatgc atgcgttcga gctcgctgct gccaaccgcc gccttcgcaa
   964081 gctcgcggac gcgcttgccg ggcttgctga gcggggtttc gcggacataa agccacagag
   964141 gcgcgaacga atggtgcagg ccgaaaacgc cggcccggtc ttccgtctcg acttcgccct
   964201 gcgcttctat gcgaaggaca gttcgatcgg cgtcgacgct gacaagatgc gtgcggttgc
   964261 caaactggtc gtcgtagctc acttcgatcg cggcgccgtc caccagcgtc ttccagttga
   964321 ggacggtttg accaggcaga tttaccggcg tgagacgcag gcgctgcagc gcgtattgta
   964381 ccggtgcgtc gtagcgatac tcggtcgtat ggctgatttt caggtgcatt tccgttcctt
   964441 cgatcacttc aggaaaaccg tgtcacggtt tttccggaag cgcgtaattc cgctcagtgg
   964501 tagaaccggt agccatcgga aatttcctga cccaagcgat tgttctggct gatgaaatcc
   964561 tcgagatact cgtgcaggcc acgatccatg atgttggcga tcgattggct gcgcagaaaa
   964621 ccaagggtcc gctcagccgt ctcgtgcgcg gcgtgccgtt tgccgtattc gcgcgcgaga
   964681 taggcgaggt tggagacgat cttctcgtag caataggcga gtgagcgcgg catgcggccg
   964741 ttcgcgatca ggaagtcggc gatgttggcg ggcctgagtt cggcatcata gacccagcca
   964801 taggaccggt gcgcggaaac cgagcgaaga atcgattccc attggacgtt gtcgatagac
   964861 gagccgaccg cggagatcgc cggcaggagc acgtaatatt tgacgtcgag aatacgggct
   964921 gtgttgtccg ccctctcgat aaaggtgccg atacgcgaga agttgaagat ctcgttcctg
   964981 agcatcgtgc cgtgaaacgc gccccggatc agccccgttc gccgcttgat cgtgtcgatt
   965041 atttccggca tgtcggtggt ccttgccctt cttgcgagga ttcccttcat ctcgatccag
   965101 cattcgttga tcgcttccca ggtctcccgc gtcagggccg tgcggaccat gcgggcattg
   965161 ttgcggccct cctcgatgca ggaaatgacg cttgaagggt tggcgcggtc gcgcagaagg
   965221 aaatcgatgg cgtcgccact cgtcagccct tcatgaacct gatcatagag tccgcgcacg
   965281 ccggcacttt gaagcactcc gtcccagtcg tcctcggccg actcgctgcg ggtcagcgac
   965341 atgcgcaatc ctgcatcgat aaggcgggca ctgttttccg tccgctcgat atagcggaac
   965401 atccagtaga ggccgtttgc agttcttccc agcatcgcct cagtcctcca gcacccaggt
   965461 atccttggtc ccgccgccct ggctggaatt caccaccaga gagccctcct tcaaggcgac
   965521 gcgagtcagg ccgcccggaa tgatctgaac cttgtcggag acgagcacgt aaggacgcag
   965581 gtcgacgtgg cggggcgcaa tgcccttctt taccatgatc ggtaccgtcg acagcgacaa
   965641 agtcggttgc gctatgtagt tgccggggcg ggatttgagc ttttcggcaa aaactacgcg
   965701 ttccttcttg gtggccgtcg ggccgaccag catgccgtat ccgccggagc cgtgaacctc
   965761 cttgacgacg agctcagcca gatgctcgag cacgtatttg aggctgtcgg gctccgagca
   965821 gcgccacgtc ggcacgtttt ccagcagcgg cttgcgcccc gtgtagaact cgatgatttc
   965881 cggcatgtag gagtagatgg ccttgtcgtc ggaaatgccg gtgccgggcg cattggctat
   965941 cgtgacgttt ccggcacggt agacatccat gatgcccggt ataccgaggg cggaatccga
   966001 tcggaaggtg agcggatcca ggaaatcgtc gtcgacacgc cggtaaagaa catcgatcgc
   966061 ctcgtagccg cgggtcgtgc gcatcttcac cttgccgtcg atgacgcgca gatccgaacc
   966121 ctggaccagt tcgacaccca tcatgtccgc gaggaaagca tgctcgtaga aggcggaatt
   966181 gtagatgccg ggggtcagca cggccacgcg gggcttgccg ttgcagcccg caggggcgag
   966241 cgacgaaagg ctctggcgaa gcagataggg ataattctcg accggacgca cccggttctg
   966301 gtggaagagc tccggaaaca tctgcatcat ggtttcgcgg ttctccagca tatagctgac
   966361 acccgaaggc gtacgcgcat tgtcctccag aacatagaac tgattttcgc cggtgcgcac
   966421 gatatcggtg cccacgacgt gggtgtaaac gccacccgac gggcgaaagc cgatcatctg
   966481 cggcaggaaa gtgtcgttct tctcgatcag tccgcgtggg atgcgaccgg cgcgaatgat
   966541 ctcctgtttg tggtagatgt cgtcgagaaa agcgttgagc gccagcaccc tttgttcaat
   966601 gccttgcgcg agccgtctcc attcacggcc ggagatgatg cggggaatga gatcgaaggg
   966661 aatgagcttc tcggaggaat cggcgtgtcc gtagactgcg aaggtgatgc ccgtcttacg
   966721 gaagatcttc tcggcttcct tcgattttgc gatgagccgg tttctgtcct gatttgaata
   966781 ccattggtgg taggtcgaat atggttggcg cgggctgccg tccgcatcga tcatttcgtc
   966841 aaatgccaaa ttcgcgtccc cttattttcg accatttgaa tacaacgcaa agtgcaatgc
   966901 aagaagcgtg cgcgttttcg gtccaggaat tttcgggagc gtggtgccga gaaaaggctt
   966961 ggcgcagcgc cgtttcgtca tgaatccgtg accgggcgct gccgaacgac cctgccgacg
   967021 ccttgggaat aggcgattgc ccgaatttag ggcgcccggt ctggttgagc atttcgagga
   967081 gcggggtcgc gccaaccgga gggcgttttc ttcattcatc tttctgtgac aaaaaccggg
   967141 acggcgcaga atcgagaggc ggcagacccg actgtgctgc tgccgtgtag aatcaaccgc
   967201 acgcactttc tctcacccgc actgaagcta accatcagaa aaattctttt gaccgaaagc
   967261 gacacccgct ctatcgcggc agcgcgatcc cgtgcggatc gtcgtggatc cttcgctcag
   967321 gaaaacatca tgcttgctcg cctggctccg gccattttcg tgctgctctg gtcgacaggc
   967381 tgggtcgttg caaaatatgc cgctttcttc gcggatcccc tgacctttct cgcgctgcgc
   967441 tacagcttcg ccattctact cttcgtttgc ttctgtcttc tgagcggagc gcgctggccg
   967501 cgttcaccga cggcgatcgg ccatgcaatc gtgtcaggta tctttcttca tggcctctat
   967561 ctcggcgcgg tatggtgggc gatcgggcag ggtgtgcccg cggcgatctc aggcattatt
   967621 gccggcttgc agccgctgat gacggctgcg gtcgcgccat ggctgatcgg cgaaaaactg
   967681 aacggtcagc agaagcttgg ccttgtcctc ggtttctgcg gcatcgcgct tgcagttgcg
   967741 ccgaaaatgc tggcgatcga tgcttccgca acgccaatcc acctgttgcc cctggcggtt
   967801 aacgtcgccg gcatggcggc cgtcacctac ggcacgcttt atcagaagcg gtatcttcaa
   967861 aatggcgatc tacggtcgat tgcggctttg caatatgtcg gagcgctcat cgtcaccatc
   967921 ccgctcgcgc tgatgctcga gaacctgcat gtcacctgga acctcgagct cgtcgcggcg
   967981 ctcgcctggt cggttctggg tctttcgatg ggagcgatcg cactcctgct ctatcttatt
   968041 cgccgcggac aggtgtcgcg cgctgcatcg ctcatctatc tggtgccgcc gcttgcggcc
   968101 ggcgaagctg cgctgttttt cggggaggcc ctgaccgtgc caatgatcct tggcacgatc
   968161 atcgcggtag cgggggtata cctcaccaat cgtaatgccg ccgagccggc gccgagcgcc
   968221 gtgctggaca cgcaaagacc gctctgaggt tctcgcacct gctgacggaa gccgctgcac
   968281 ttctccaaac ggaaaagcgg cgggcttccg cccgccgctt tcaagtattc cgatgcttca
   968341 cgagcgtgcc ttaccctcgc ggcgcgcgat tttccgcgcg gcgcatgccc cgggcgcctt
   968401 cattgcggtt gctgggctgg ccttcattgc cgcgccggcc gtcacgcttc gggcccggac
   968461 ggccatggtg cttcttggct tcgtggttgc ggttgccttc cggacgaccg tcctggcccg
   968521 gagcacgatg atcgcggcgc tcgtgctgtt gcgaacggtc gtcgcgcaac agttcgtcgc
   968581 cggcgaagcc gccggctgcc gactggcgtt gtggccgatc ccggcgaggt ccgccctggc
   968641 gctgtcctgc gccattgccg cgggactggg cgttgccgcg accgccgcgt cccttggacg
   968701 ggcgggcctg gtcggccgga acttctccgc tggcgacggc aatctcgatg cccatcagct
   968761 tttcaatatc gcgcagcagc cggatttcgt ccggggcgca aaaggcgatc gcaataccgt
   968821 cgcggccgtt tcgggccgtg cggccgatac ggtggacata agcgtcggcc acctccggca
   968881 ggtcgtagtt gtagacatgc gtcacgccgg gaatgtcaat gccgcgtgcg gcgacatcgg
   968941 tcgccacgag tacacggatt tcaccatcgc ggaaggcttt cagagcgcgc tctcgctggc
   969001 cctggctctt gttgccgtgg atcgaggcgg ccttgaaacc gacctggtcc agatgcttca
   969061 tcagcttttc ggcgccatgc ttggtgcggc tgaagaccag cgacaatccg tccggatttg
   969121 cggtcagcgt ctgtttgagg attgtcgtct tcaggtcctt gcccggaacg aagtggacat
   969181 attgctcgac cttgtcggcc gccttgccgg gccgcgtgac ctcgaccttg accggatcgg
   969241 tgagatattc gccggcaagc tcggcgatca gcttcggcat ggtcgcggag aagagcagcg
   969301 tctgacgatt cttcggaacg agcttcgcga tcttgcgcag gtcgtgaata aagccgaggt
   969361 cgagcatctg gtcggcctcg tccaggacga ggtagcgtcc ctgggtgagg gtcacagcct
   969421 tgcgggagat gagatccagc agacggccgg gcgttgcgac gagaatatcg acgccgcgcg
   969481 ccagctgttc ggtctgcttg ttgatcgaca cgccgcctac cacgactccg actttaatcg
   969541 gtgtcttctt cacgaagagt ttaagattgg tggcgatctg gttgacgagc tctcgggtcg
   969601 gcgcaaggat gagggcacgg atgttgcgcg gatcggggcg tttgccgtcg gcctgaagct
   969661 tttcgatcat cggcaggcca aaggcggccg ttttgcccgt gcccgtctgg gcgaggccga
   969721 tgagatcgcg gccttggagg acaagcggaa tggcctgggt ctggatgggc gtcggcttct
   969781 cgaaaccgtt ggcggtcagt gtcgccagga tctcctgcga gaggccgagc tctttaaatg
   969841 tggacaaagg gatatacctt tcggggacgc caaaagcatc cgccggaatc gccctttgca
   969901 attccggtgt gatctggcgt caagaacccc gcgtgaattg ggaacttgtg ggttaataga
   969961 aaatcgtcag gcgcctgtgc tgccgcggag tgcggacatg tttcgcgctt ttccttcttc
   970021 acggcttcaa agttttgccg agggcgcgct cacgcggcgg ccggaaggtg acgcaggcct
   970081 tagatcgttg ttttaagccg gaaagtcaag cggcatcttt tgcaagtgcg aacacgcctt
   970141 tcatccttgg cgtgtgggcg cgttcgaagc cgcccggtga tgcggcacaa tgcgcagcga
   970201 tcacaatgct ttcaggtcga tccaacccca aagcaccgtg atccggaggc cgcgcatgag
   970261 ctatgtccct tgcggaagaa ggaactgggc gtacaatccg gccgttaggc tcgcgatggg
   970321 acatagctgg ctggtgacga gccgatgatg cgcgcagggc gcgtgacacc gattgcgaca
   970381 gatctccggc ggcaaggaac cggatgcggt ctcagccgtt ctgtccgcgg gccccgctga
   970441 cctacctgcc atctacacgg gagacaatag tgcgaaaccg gatctggata ctggcagccg
   970501 atggaaacac ggcgcgcatc gtaaaagacg tcaacctgct gaaagacggt aggcagcagc
   970561 cagaggtgga aacattccaa atcgaaacca aacgccgcca ggacatcatg gccgataagc
   970621 ccggacgcag tcattcgtcg gccggtcatg gtcgctctgc aatggaatac agcagcgatc
   970681 ccgtgcgcga ggagcagcat cgtttcgcca tggaaatcgc cgggaagctc gaacactatg
   970741 ccgatgagcg tgcgttcgag aacctggtga tctgcgctgc gccgagaaca ctcggcgacc
   970801 tccgaaagct gctttctcac caggtcaagg aaaagactct cgcggagatc gaccgcaatt
   970861 gcgtctccgt tccgaccgat cagttgatcg cgacggtcaa gtcggtggtc ttcccgggat
   970921 aggcgcagcc ggattttcgc gcgcctggat catgaacgtg atcgcttcca aagagttaga
   970981 gcgcggtgcg ggcggagatc cgcgctcgct tttcctcata ttgctggctt tacgccgcgt
   971041 aacatctctc gctttccggc aaaaccgggg cgacgctcga cggcgaaccc tgctgcggcc
   971101 agattgcgcc gtacgaagcc ggccgcggca taggtcgcga agctgccgcc gccgacggtt
   971161 ctgtcgaata ccagctgcat cagctctttc gaccacatgt ccggattgcg cgagggcgcg
   971221 aatccatcga gataccaggc gtcgaaattg ggaggggacg tcgagacgcc gccgaacgcc
   971281 gcgccgataa cgatggtcag gcggacttct gcggtgaagt caatgtccac gcgggcgacc
   971341 gggtccgtcg gccaattggc gacaagcgct tgccgctcct cgtcgatttc cggccaatgt
   971401 gccagcgcac ggtcgatctc gccggcgtgc atcgggaagc gctcgaagga gacgaaatgg
   971461 agacacttcc ggggcgcagg cacccgcttc cattgtcgcc acgtctcgca gaaattaagc
   971521 ccggtgccga agccgagttc gccgatggtc attgcgccgc cggaccccca gcgttcgggc
   971581 agtccgttgc cggcaaggaa gacatggccg cattccagcc gtccgtcggt acggcaataa
   971641 aaatggtcgc caaattccgt cgaatagggc atatcgccct cgtgccattc gaggttttgc
   971701 cgcgagggtg aagggctctt gccgggatcg gttcctgtca tggtgaaccc gataattcta
   971761 ccgtccggga aggtcaatct atgtgcgaag ttttgatcgt gggcggcggc atcatgggcc
   971821 tgtgggccgc tgtgatggct gggcgcgccg gctttacgac gcggcttctc gagcgatggc
   971881 ggatcggttc cggcgcgagc ggcggtttcc tcggcgcgct catgccgcat atgcctgacc
   971941 gttggaacga gaagaagcag tttcagttcg atgccctggt gtcgctcgaa ggcgagatcg
   972001 ccgagcttga agccgcaacc ggcctctcgg caggctaccg ccgctccggt cgggtcatgc
   972061 ccattgggag agcacatctg cgcgagatcg cccacggccg tgagcgggat gcggcacaga
   972121 attggcgagg gccggcacac caataccttt ggcaggtcgg ccacgccgat gaaggcggtt
   972181 ggccggccgc cgatgcggcg cccttcggta tcgtccagga cacgctggcc gcgcgggtgg
   972241 cgccacgcaa ccttcttgcg gtgctgcgtg ccgcactgga ccaatttccg catgttcaat
   972301 gcgaggaagg tgcggaagtc gtctcgatcg agccggcacg cggccggctt ttgctcgcgg
   972361 acgggcgcgc tttgaccttc gatcgcctga tcctcgccgc cggcgtcgca agcttcggct
   972421 tcatcgatgg tctgacacag cccaggcggt ctgcaagcgg cggtgccgtc aagggccagg
   972481 cagcgctgtt tcgcgccgat gtcgacaaag ccttgccgat catctttacc gaagggcttt
   972541 atatcgttcc gcacgaaaac ggacaggtgg cggtcggcag cacgagcgaa agccggttcg
   972601 acgaccccaa ttttaccgat cgtcagcttg atgccctgct tgcgcgcgca atcgatatcg
   972661 cgcccgtttt gcgtagcgcc acggtaatcg aacgctgggc gggcctgcgt cccagggcga
   972721 cagggctcga gcccatggtt ggtcgtcacc cggatcacga aaggcttttc gtcttgaccg
   972781 ggggcttcaa ggtgagcttc gggctggcgc atgcattggc acgatccgtg gtggaagaga
   972841 tcgccggcgg cggcatgaac gccttgcctg agagctttca atgtgcgcat cacgtcgccg
   972901 ccctgcgcta gtctgggcga cgcgcgcttc acgacggcgt tacgggccgc gaaattcgtc
   972961 aatctgtcac gcaaatcact taacacgcgg gccattggat tattcgcttc cacggacttc
   973021 cggagcatgc ctcatgcgct acgcgatctg tttcaccccg ccgatgggag acccgctttc
   973081 tgtcacggct gccagttggc tcggccgcag cgtgtacacc ggggagccgg tggaactgcc
   973141 gtcgattgcc ggtctggccg tgtcagatat agcatttcac accgccgttg cgcgccgctt
   973201 cggatttcat gcgatgatca tggcgccctt ctgcctgagg ccctgcatgg acgaagcgca
   973261 gttgctcaag gccatgatgc tcttcacgag tgacgaaacg ccttttgaaa tcgaacggtt
   973321 ggaggtcgcg cgtctcagcc agtgctgggg gctgatgccg cagatgccga gccagccgat
   973381 gcatctgctc gccgcgcgcg tcatccaggc gttcgatcgg ttccgctctc cactcagtga
   973441 ggaagacatc gagcgagcgg accccgacag gctcacggct ccacagttca ccaatctgca
   973501 tcggtggggc gacccccatg tgatggacga gtatcgtttc cacatggctt tgaccgggcc
   973561 cttgaatgcc gatgccggac gccgggtgga ggcacccttg cgccaacttt tcgagtcgtt
   973621 gctgatcgaa ccccttttga ttggcagcct ggctctgttc atcgagcacg aacccggagc
   973681 tccaatgcgc gtgcattcgc agcatccgct tggcaaggtt tccgcgcgcc cgcgcggcga
   973741 caaggccaga catcttgttg cggcgcggtc agttcaggat gatgccgcaa caccgccagc
   973801 cccggtgacg gccggaattt ccagcggcct ggcgtttaga gcgggatgaa caaggtgcgt
   973861 gcggttttcc gcccgcgtgc cgcgctgagt aatcgaggat tctattcccg atgccgccat
   973921 ttttcacctc gacaatccca tgcgcggtgc taccgttccg ggaaattcga agggtgaatg
   973981 atgaacgaga attcctatcc gcgtgacttc gtcggctacg ggcgcaggcc gcccgaggcg
   974041 cgttggcctg gggacgccaa catcgctgtc caattcgtgc tcaactatga ggaaggcggc
   974101 gaaagctgca tactcgacgg cgatccggcg tccgaatgtc tgctgtcgga gatcgtcggc
   974161 gctcagccct gggccggaca gcgcaacctc aatatggagt cgatctacga gtatggcgcc
   974221 cgcgccggtt tctggcgcct gtggcggatg ttcacaagcc gcggcgtgac gctgacggtc
   974281 tacggtgtga cgctcgccat ggcacgcaat ccggaggccg tcgccgccat gaaggaagcg
   974341 ggatgggaga tcgccagtca cggtctgcgc tggctcgaat acaaggatgt tcccgaagag
   974401 gtcgagcgcc agcatatccg cgaggtcgtg cggcttcaca ccgagctgac cggcgagcgc
   974461 ccccttggaa tctaccaggg caagccctcg gcaaacacgc tcaagctcgt gctggaggag
   974521 ggcggtttcc tctattcctg cgattcttac gcggatgagc ttccctactg ggtgccgggg
   974581 cggacgcccg acaacccgca tctcatcata ccctatacgc tcgacgccaa cgacatgcgt
   974641 tttgcgacca gtcagggctt caactcgggc gaccagttct tcacctatct caaggatacg
   974701 ttcgacgtgc tctatgcgga gggcaaggaa ggcagcccga aaatgatgaa tgtcggcctg
   974761 cattgccggc tcgtcggacg gcccggccgg gccgcggcgc tcgcgcggtt catcgattac
   974821 gtgacctccc acgacaaggt ctgggtgccg cgccgcatcg acatagcgcg ccactggtac
   974881 gaacatcaca agccgacgga ggcgcgctga tgctgactcg tgacgatttc atccggcgct
   974941 ttggtggcat cttcgagcac tcgccatggg tggcggagcg cgcttacgac cgtgccgctt
   975001 ccgccggatt gaccgcaggc aatgtgcatt cggcgctctg caacgccttc cgcgaggctt
   975061 cgcccgcgga ccggcttcgg gtgctgcgcg ctcatcccga tctcgcaggc aagctggcgg
   975121 tcgccggcga actcacggcg gattcaaagg ccgagcaggc gtccgccggg ctcgacaggc
   975181 tctcccccga agaacatgca cgcttcacag aactgaattc ggcctatatc aagaaattcg
   975241 gctttccctt catcattgcg gttaaggggc tggtgaagga agacatcctc gccgccttcg
   975301 agcagcgcat tgacaattcc gcggaagagg aatttgaagc ggcctgtgcc gaagtcgagc
   975361 ggattgcccg cctgcggctg cgatccatgc ttccgggaga cgactatgcc tgacaccaat
   975421 cctgatcgtt ccgagggaac acctcgtcct gcgtccgagc acccgggcgt ctgcgggcag
   975481 agaaccggaa cggcaggttg atgtcgcatt tgctttcgat cgagcccctc acgagggagg
   975541 ctttcgcacc gttcggcagt atcatggagg cggaccccgc ctccatgcgc tttatcaatg
   975601 gcggcaatac cgagcgattt cacgcactgg cgcgcgtcga tgcggcgggt gagggcgccg
   975661 gtgcaatcat caacatcttt cgcgggcaac cccgtgtttt tccctattcc gtgacgatga
   975721 tggagcgcca cccgctcggt agccagagct tttcgccgct ccaggaccgg ccatggctgg
   975781 tcgtggtcgc cgaagatgaa ggcgggcggc ccggccggcc aagggtcttc ctcgcaaacg
   975841 gcagacaggg cgtgaactac gcccgcaata tctggcacca tccgcttatg tcggtgggcg
   975901 ttgcaagcga cttcatcgtc gtcgaccgag aggggccggg cagcaatctg gaagagttct
   975961 attacgacga ggctttcgtc attcgcgatc cgtttgaagg cggatgacgg agacccagca
   976021 gattttcgtc gaggactgac gtggcgcacc cttcctccgt cagctccgaa atggtttgtt
   976081 ttgaggtgcg catccagttg aaagtcgagt tcgcatctcg agacatcaga tgtctggctt
   976141 gttagaaccg atgaagctta tattctcgga tggaccgaaa gcgcgcgatt tttcctgaag
   976201 tgctcatggc tatcgtgatt ttgatgagga aataagatga gcaagacggg gcgcctgacg
   976261 acccatgttc tggacacagc cctcggcaga cccgctcagg caatgaggat cgatctctat
   976321 cgtctggaag gcgaggtgcg gcagctgatc cgtacggccc gaaccaatag cgacggccgt
   976381 atcgacgagc cgcttgtcga gggtgtcgat ttcaccaacg gcacctacga actggtcttc
   976441 catgcgggcg aatatctcag ggccatggac gtagcgcttc cggatcccgc gttcctggac
   976501 ctggttccgc tgcgattcgg tgtcgcggac agtcgaaacc attatcacgt gccgctgctg
   976561 ctctcaccct acggctattc cacctatcgc ggcagctgag taagcgcggg gcagcagcag
   976621 gctgttgccc gtcaaacggc cttaatcggc gatcacgtcg aggccgacat ctgtgatgcg
   976681 gcgcttgccg cagagtgcca tggtcgtatc catctccttg cggataatgt cgagcgcgat
   976741 ccgcacgcct tccttgccga gcgcgccaag gccgtacagg aaagggcggc cgatataggt
   976801 gcctttagca ccgagcgcga ccgccttcag cacgtcctgg ccggaacgaa tgccgccgtc
   976861 gagatgcacc tcgatctggt cgccaacggc gtcgacgata cgcggcagca tgctgatcga
   976921 ggaatgcgcg ccatcgagct ggcggccgcc atggttggag acgatgatgg catcggcgcc
   976981 ggacttggct gccattttcg catcttccgg atcgagaatg cccttgagga tcagcggacc
   977041 gccccagcgc tccttgatcc actcgacgtc cttccaggaa agctgcgggt cgaactgctc
   977101 gttcgtccag acctgcaggg aggagagatc gctgacgctc ttggcgtgac caacaatatt
   977161 gccgaaggtg cgcctgttgg tgccgagcat tttcatgcac cagccgggcc gcgtcgccat
   977221 catccagaga tgtttcggcg tcagtcgcgg gggcgcggag aggccgttgc gaaggtcttt
   977281 atgacgctgg ccgaggatct gcaggtcgag ggtcaggacg agagccgagc atttcgcagc
   977341 cttggccctg tcgatcaggt tgagaacgaa ttcgcgctcg cgcatgacat agagctggaa
   977401 ccagaacggc ttcgtggtcg cagaggcgac gtcctcgatc gagcagatgc tcatggtcga
   977461 gagggtgaag gggatgccaa acgcttcggc cgcctgagct gccagcatct cgccgtccgc
   977521 gtgctgcatg cccgtcaggc cggtgggggc gagcgcgacg ggcatggaga ccttctgccc
   977581 gatcatggtc gtctcgagcg accgatcgga catatcgacc agaacccgct ggcgcagctt
   977641 gatcctggcg aaatcctcct cattggcgcg gtaggttccc tccgtccagg cgccgctatc
   977701 cgcataatcg aagaaaagct tcggcacgcg cctcctggca agggccttga ggtcccggat
   977761 ttcgagaatc tgcgtcatgg atcagcctca tcaagtgaac gactgccgag cccttatcat
   977821 gttttcgaag accttgtaat agttgcggaa agtgagaggt caaaatatat tacctctcac
   977881 ttccactcgt gctccggcag ctaaagcatt gatttgcatg gctttcctgc gacgtaggtc
   977941 tcgacgacag cgcggtcgtc acccatcgtc tgcaggagga aaagctcgtc ggccagagaa
   978001 ttgacaactt cggccctgag tgccattgcc ggtgttgccg ccatgtcgag gaccgcgagg
   978061 tcggcatccg tgccgggctc cagcgtgccg atgcggccgg cgagcgacag cgcctcggca
   978121 ttgccgcgag tcatcatgta gaagctgtcg aaggggttca gcctttcgcc ttgcaactgc
   978181 agaatcttgt aggcttcatc gagcgtcttc atcatcgaat agctggtgcc gccgccgatg
   978241 tccgatgcga ccgagacgcg caccggccgc tgtcgccgcg tcagtgcccg caaagggaac
   978301 aggccggaac caaggaaaag attggaggtc gggcagaaga cggcgatcga gccggtgtcg
   978361 ctcatggcat cggcttcacg ctcggacagg tgaatgcaat gaccgaagag gcttttcggt
   978421 ccgagcagac cataccgggc gtagacgtca gtatagtccg ccgcttccgg atagagttcc
   978481 agcgtgtagg cgatctcgtc gcgattttcc gaaaggtgcg tctgcacatg caggtcggga
   978541 aactcgtcga cgagcgatct cacggcctcc atctgctccg gggtcgaagt gatcgcgaag
   978601 cgcggcgtga tggccacatg gttgcgcccc ttgccatgcc agtccgcaat gaccgcccgc
   978661 gtttcatcat agctcgtctc gggcgtgtcg agcagtccct ggggcgcatt gcgatccatc
   978721 atcaccttgc cggccaccat gcacatgccg cgcttcacgc tctcggcgaa gaaggcgtcg
   978781 gcggacgttt tgtgtacgga acaataggct gcggcggtcg tggtgccatg gcggaccatc
   978841 tcgtcgaaga aatgccgggc gatcctctcc gcatgcgcag tctcgacgaa ccggcattcc
   978901 tcgggaaaag tgtagctgtt cagccattca agcaggttcg ccgcatagga ggccataacc
   978961 tgcatctgcg gaaaatgcag atgtgtgtcg atgaagcccg gtacgataag atctggccgg
   979021 tgatcgacct ccgccacgtt ctcaggtgca cccgcctgga ccatcgcgta ggcgccggat
   979081 gcggtgatca cgccgttctc gacgagaagg gcgccgtcgc tctcataggc ataggaggct
   979141 ttgtcgtcga tgccctgcgg ttcgcgatgg aagcttaaag tgcggccgcg aatgaggatg
   979201 gctgtcatcg tgtctccccg acggcgcttt cgaaccaggc cgttaccagc cggcgctctt
   979261 catccgtcat ttcggttatg ttgccgggcg gcatggcatg gctgcgcccg gcctggatgt
   979321 agatttcccg cgcgcgggca gcaatctctg cctcgctttc gagcttgacg ccgttcggcg
   979381 gccgcacgat cccttcatag gccggctcgg ctgcgtggca catgctgcag cgcgtcgaaa
   979441 tcgtttcact gactgcgggg aaatgtgcgt tatcggcaaa gcgctggaac tcaggggctg
   979501 tctcggcacg ctcttcgacc gtcagtattt caggcaccgt cgagagccac atgaccagga
   979561 tgaacaggag tgccgtgaca gcccaggtcc aggtaggctt gcccttgcgc gcatgcgttg
   979621 tgttgaacca atggcggatc gtcacgccca tcaggaagac gagtcccgcg atgacccagt
   979681 tgaaggccgt cgcgaaagca agcgggtagt ggttcgagag catgaagaag atgacgggca
   979741 gcgtcaggta gttgttgtgc agagagcgct gtttcgcctg cgcgccgagc ttcgggtcgg
   979801 gcgtgcggcc ggcaataagg tcgccgacga cgatcttctg gttggggatg atgatgaaga
   979861 agacattggc cgacatgata gtagcggtga aggcgccgag atggaggaat gcggcgcgac
   979921 cggtgaaaac ctgtgtatag ccccaggcca ttgcgaccaa taccaggtag agcagcgcca
   979981 tcagtcccca ggtgctctta ccgaccggcg acttgcaaag cagatcgtag aggatccagc
   980041 cgagaccgag tgaggcaagc gagataagga tcgcggtcat ggccgagatg tcgaggacat
   980101 gccggtctat gaggaagagg tcggcgccgc cgtaatagac gatacagagc atggcgaagc
   980161 ccgacagcca tgtcgcatag gattcccatt tgaaccaggt gaggtgctcc ggcatggcgg
   980221 ccggcgccac cagatatttc tgtatgtgat agaagccacc gccgtggacc tgccattcct
   980281 caccataggc gccagggggc agatggtcgc gtctgacgag accaagatcc agagcgatga
   980341 aatagaagga cgagccgatc caggcgattg cggtcacgac gtgcagccat cgagcggcga
   980401 aggccagcca ttcccaggcg atggcgaatt catacattcg ggaatccttt tttcaccttc
   980461 gcacaacctt gcgagaaaaa gggtgaacgg ggaaggggca tttgaccgct tgtcccattt
   980521 cgcgagtttc ggtcctggcc gaaaagtcga actaagcagt caatgcgcgt ctcgatgggt
   980581 gtcggggtcg agcttgccga ggatccagtc ccggaaggct cggatcttcg gggcgttgcg
   980641 gcgggcgtgc ggatagacga gccagtaatc gtggccgtcg ctgcatcgca gttcgaacgg
   980701 ctggtaaagc cggccgagcg ccacatcgtc gctatagaat tcaggcatca ggatcgcgac
   980761 gccctggcca gcgaccgccg cccgagcttc gaaggcctgg gcgccgagcc ggcttcctgg
   980821 acgcccgtcc agatccggat cgtccacgcc cgcagcgcga aaccacaagg accaccaggg
   980881 atctcgaggg tcgatgatgc ggagcttcag gaggtcccgc ggagtgcgca cgccaccgac
   980941 cgtctccgca agggcggggc tgagcatcgg tgtaaactcc accctcatca gcctatggct
   981001 ggcgaggccc ggccagtcgc ccatgccgga gcggattgct acgtccaccg cctccttgtt
   981061 gaaatcgata atcgcgtcgt ttgccaccag acgcaccgca atattcggat gctccagttg
   981121 gaaggtcccg atttcccggg cgagccattg cgaggcaaag gttgccgtcg agttgatgag
   981181 caaggctgct tctgcattcc cgcgggccga ggcgactgcg tcgtgcagca tctcgaaggc
   981241 ttccgtcact ttcggagcca ggtgctgccc gacttccgtg agtgcgatct gccgcgggcg
   981301 tctcaggaac agcggctcgc cgatattctc ctcgatcagc ctgatctggt agctgaccgc
   981361 cgtctgggtc atgccgagct cgtcgcccgc cttggtgaaa ctcccgaggc gggcggctgc
   981421 ttcgaagacc ctcaatgcat tcagcgggaa ctgcttcgac atcttcatgg ataagttctc
   981481 ttgatgcata cagacggatg ttcgattgga tttcgaacat ccctccaggc atcctgaaag
   981541 tcaacttcac cactttgaaa aggtgccaag atgtcttgcg atgtatcgga atttgctgaa
   981601 agaaggccgc ttatccctct gggcggggtc gtccggcttg ccgcctcggc gctacgccgc
   981661 atgagaggcc acagcatcag tctcgacctc gattcaacat cggactacat gaaaaaggac
   981721 ttgggacttc tcgacggccg catggcccgg caggacgacg acattctgcg gtagaggcta
   981781 ctcatccggg aaaggctcta agccgctcca ccgccatcag gacgcgctcc ggcgttgcgg
   981841 gcgtatcgag gcgggggcac tcgcgatagt cgatgatgct ggcgacggcc atcgacaggg
   981901 cctcgacgac ggaaatcggc agcatgaggg gtggttcccc cacggccttc gatttgccga
   981961 tcgtctcttc cagattttcc gaccattcgg cgaggcgcac gttgaagatc ttcggccgat
   982021 ccgaagcgag cggtatcttg taggtcgaag gcgcgtgcgt ccccagccgc cctttctcgt
   982081 cccaccagag ctcttccgtc gtaagccagc ccatgccctg aacgaagccg ccctcgatct
   982141 ggccgaggtc gatggccgga ttgagtgagc ggccgacgtc atgcagcacg tcgacccgat
   982201 cgaccatgta ttcgcccgtc agcgtatcga ccgaaacctc ggatatagcg gcgccataag
   982261 caaagtagta aaacggcgtg ccgcggccgg cggcccgatc ccagtggatg tgcggcgtcg
   982321 catagaaacc ggcggcggaa agctggaccc gtgccccgta tgcctcctgc accaattgcg
   982381 caaaagggat cagctcctgg ccgatcctga catgattggc ctcgaaggtc acgttctcgg
   982441 ctgtcgtctg ccaccgctcg gctgcaaagg cgaccagtcg ctcttttatc tgatgtgcgg
   982501 catcgaaggc ggccatgccg ttgaggtccg agcctgagga ggcagcggtc gcggacgtgt
   982561 tcggcacctt gccggtcgtc gttgcggtga ttttcaccag ttcgatgtcg atctggaaac
   982621 tgtctgcgag gacctgcgcc actttcgtgt agaccccctg gcccatctcc gtgccgccat
   982681 ggttcagatg gaccgagccg tccgtgtaca cgtgtacgag ggcacccgcc tgattgaggt
   982741 gggtgagggt gaacgagatg ccgaatttca cgggcgtcaa cgcgataccc ttacggatca
   982801 cgcggctcga tctgttgaat tcgacgatcg ccgcccgccg cgctcgataa tcggcgctcc
   982861 cctccagctc gtcgacgatc cggccgatga tgttgtcctc gatcgtctgg tggtagggcg
   982921 tgacgttgcg gccggaagcc gcatccccgt agaagttcag cttgcggatg tcgagcgggt
   982981 ccttgccgag cgcataggct atctcttcga tgatccgctc accgccgagc atgccctgcg
   983041 gtccgccgaa gccgcgaaat gcggtattgg aaaccgtatt ggttttaagc ggttgcgagg
   983101 tgagtttcac atgtggatag aagtaggcat tatccgcatg gaaaagggcg cggtcggtga
   983161 ccggcccgga gagatcggcc gaataaccgc accgagcggc ataatttgcc tggaccgcac
   983221 ggatgcggcc atcgtcattg aagccgacgt cgtagtcgac gaggaagtcg tggcgcttgc
   983281 cggtggccac catgtcgtcg tcgcggtccg ggcgaaactt gacggcacgg cgaagcttgc
   983341 gcgcggcgac cgcggcgagt gccgcgaact ggttgccctg ggtttccttg ccgccaaagg
   983401 cgccgcccat ccggcggaca ttcactgtga cggcgttgga tggaacgcca agcacctgcg
   983461 cgaccatacg ctgcacttcg cttgggtgct gcgtggagac ccagaccgtt atttcgtcgt
   983521 cctcgccggg gatagccagc gcgatatgcc cttcgagata gaaatgctcc tggccgccga
   983581 tccgcatgcg cccctggagc cggcgagggg cccgctccag ctcgccaagg gcgtcgcccc
   983641 gctcgagcgt cagcggcggg gttatcagag tgccaccagt cgccatagca tcgatcacat
   983701 caatcgccgg aggcaagtcg cgataggtga tcttcgcaag ccgtgcagcg cggcgggcga
   983761 tatcccgtgt ctcggcaatg accgcaaagg ccggctgacc atgaaactgg atgagaccgt
   983821 cggcgagcac cggctcgtca tgcaagtggg tggggctgat gtcgttggaa tgtggcatgt
   983881 ccctggcggt gaggacggaa acgacgcccg gcagtgcggc gacggcggag aggtccattg
   983941 cgaggatttc cgcatgcggc cggtccgtca ggccgagggc gccatgcaac gtgccgttcg
   984001 gttccggcat gtcatcgata tagtcggcgg tacccgccac atgcttgtgg gcgctgtcgt
   984061 gacggagcgg cgcatgcatg gggccggtga tgttgctgac ttcgaggttg ggtttatcca
   984121 tgtggatgtc agcactcatg ccacctcctc gaaccgccgg agctgcgccg tctccccggt
   984181 gctctcgagg aagaagcgca tcagcagatt cttcgccgca agcaggcgat aggcgccggt
   984241 ggcgcgccag tcggtgatcg gctggtaatc ggtatcgaag gcgctctggg cgtcgcgtat
   984301 cgtcccctca ttccataatt cgccgagcag ggccgcttcg acgacctttg cccgtttcgg
   984361 tgttgccgcc atgccgccga aagcgattct cgccgccttc acccgatctc cgtcgagcga
   984421 gatgcggaag gcgccaagca gcgcggaaat gtcctcgtcg cggcgcttcg agatcttata
   984481 ggcggcgaag cgctcccccg cgggcagcgc cgggacgaag atgctttcga cgaattcccc
   984541 cggcctgcga tcctgcttgc cataggcgat gaagaaatcc tcgagcggga gcgtgcgcga
   984601 accgccatgg gagcgcaggg taagcgtcgc accgagcacg atcagcggcg gcgggctgtc
   984661 cccgatcggc gagccgttgg cgatgttgcc tcctatcgtg cccatgttgc gcacctgatc
   984721 gccaccgacg cgatcgagaa gccggccgaa cgacgggtag gcggaggaaa gggcctcgta
   984781 tgccgccgag tagctgacgc ctgctccgat cgtcagaccc gcttttgagc tctcgatccg
   984841 ctgcagctcg gcgatgccgt taacgaagac gaccgtattc agcggtcgca tctgcttcgt
   984901 cacccaaagt ccgacatcgg tgcagccggc gacgatcgtg gccgcgggac gatcggcgag
   984961 gacacgtgcg aggtcggcag cgtcggcggg tacaatcaga cagtccacgc cgctgcggat
   985021 ttcgatcctt tcggcttgtc tcagctcctg caggcgtgcc cttaccgcct cccgcacgcg
   985081 ggtgatcggg tcgaagagaa cgtccgggcg atccgccgcc gcggcctccg ccgcgcgcac
   985141 gatcggttcg tagccggtgc atcgacagag attgccctgc agtgcctttt cgattgccgc
   985201 gcggcccggt ctgtcgttgg tcagccacag cccgtacagc gacatgacga ttccaggcgt
   985261 gcagaagccg cattgggagc cgtgaaaatc cacgagtgcc tgctgcacgg gatggagctt
   985321 cccgtccttg ccggccaggt gctcgaccgt gacgatatgt gtggcgttga gtgagcccat
   985381 gaaacgaata caggcgttta cgctctcata gacgagggta gtctcgcctc cttcgccatc
   985441 atgggcaagc cggccgacga gcaccgtaca ggcgccgcag tcgccctcgg cacagccttc
   985501 cttggtgccg gtgaggcggc gctccagcct cagataatcc agcagtgtcg ctgtcggggc
   985561 aacatcggaa agggcgatct ctgtgtcgtt caggatgaag cggatgctgt cgggtgcctg
   985621 ttccatgcca ttcctctgcc ctcagtcgtg gactactgcg ccgtccaccc gccatccatt
   985681 gagacatgcg tgccggtgat ctgggaagcg tcgtcgcttg caagataaag cgccagagaa
   985741 gccacctgtt cgacggtgat gaactttttt gtcggctgcc ccttgagcat cacctcattg
   985801 atcacctgct cctcggttat gccgcgcgtt ctcgcctggt ccggtatctg cttttcgacg
   985861 agcggcgtta gaacgtagcc ggggcagatc gaattcacgg taatgccgtt ctccgccact
   985921 tccagcgcca cggtcttcgt caaccccatg ataccatgct tggcggcgac gtaggcggac
   985981 ttgaaggggg atgccacgag gccatgcgca gaggcaatat tgatgatccg gccccagccg
   986041 tttttcttca tcggtggaat ggcggcacgg atggtgtgaa aggaggagga gaggttgatg
   986101 gcaacgatcc ggtcccactg ctcggcgggg aagtcttcga tcttttcgac gaactgcacg
   986161 ccggcattgt tgacgaggat gtcggcgccg ccgaagcggg atgcagcggt cgccatcatc
   986221 tcggcgatct cggatggctt ggtcatgtcg gccgggtggt gaagcacgct gccggacgtc
   986281 aagccggcga cttcgtccgt gacagtcctg atttcgtccg ccgtgccgaa accgttcagc
   986341 acgatgttgg ccccggtctt cgccagagcc cgggcgatcg ccaggccgat accgctcgta
   986401 gaacccgtta tgaccgcagt cttaaccatt ccagctcact ccctcctgac gctatccctg
   986461 tttttcgcaa cgcagcactc tcagcctacg cgcaaaggcg cagcggtgac aattgtgttt
   986521 ttccgcggtg ttctaccggg tgcacagcag tgcaggcatt cgcataatca ttcagagaaa
   986581 gttgcgtttt gttttcgttt gacattcgtt tttctctcgt attgaagtcg tgcgaatgtc
   986641 gctcttgagg aagggcgtgc tgaggagggg catatgggcg gatatattct cgcgatcgat
   986701 cagggcacga cctcgacccg cgcgatcgtt ttcgacggca accagaaaat tgccggcatc
   986761 ggccagaaag agttcaagca gcattttccg aaatccggct gggtcgaaca cgatcccgag
   986821 gaaatctggc agaccgtcct cagcacagtc agggaagcaa tcgagaaggc cggcatcggc
   986881 gcgagcgacg ttgccgcgat cggcatcacc aaccagcggg agacggtcgt tgtctgggag
   986941 cgcgataccg gcaagccgat ccacaacgcc atcgtctggc aggaccgccg caccgccgcc
   987001 ttctgcgaca agctcaagaa gaagggattg gaaaagacct tcgtcaagaa gacaggcttg
   987061 ctgctagacc cctatttttc aggaacgaag ctcaattggc tgctttccaa cgtgaaggga
   987121 gcgcaggcga gggcggcgag cggcgaactc tgcttcggca cgattgatac gttcctgatc
   987181 tggagattga cacaaggcaa gtgcttttgc accgacgcaa cgaatgcctc gcgcacgctc
   987241 atctacaaca ttgctgagaa cgcctgggat gatgagttgc tgcgcatttt gcgcgtgccg
   987301 aagcagatgc tgccggaggt caaggactgt gcggccgatt tcggcattac cgatccgtcc
   987361 cttttcggcg cggcgatccc gatcctcggc gtcgccggcg accagcaggc ggcaacgatc
   987421 ggccaggcct gtttcaagcc cggcatgctg aaatcgacct atggaaccgg ctgctttgcc
   987481 ctgctcaata ccggaaagga tatggttcgt tcgaagaacc gtctcctcac caccatcgcc
   987541 taccgtctcg acggcgaaac gacctatgcg ctcgaaggct cgatcttcgt ggccggtgct
   987601 gccgtgcaat ggctgcgcga cgggctcaag gtcatcaagg cggcacccga tacgggctcg
   987661 cttgccgaga gtgccgatcc ctcgcaggaa gtctatctcg taccggcctt taccggcctt
   987721 ggcgcgcccc attgggaccc ggacgcgcgg ggcgcgattt ttggcatgac gcgcaacacc
   987781 ggtccggcgg agttcgcgcg ggctgcactc gaagccgtct gctaccagac ccgcgacctg
   987841 ctggaggcca tgcacaagga ctggcgccgc aacggcaatg ataccgtgct gcgtgtcgat
   987901 ggcggcatgg tcgcctcgga ctggacgatg cagcgcctgt cggacctcct cgatgctccg
   987961 gtcgaccggc cgatgattct cgaaacgacg gcactcggcg tcgcttggct cgccgggagt
   988021 cgcgccggcg tctggccgaa ccaggaagcg ttcgccaaat cctgggctcg cgaccggcgc
   988081 ttcgagccac aaatggacga gaccacgcgc aaagtgaagc tcaagggttg gcgcagcgcc
   988141 atcaagcgga ctttggcggc ggcctgaacg cgtcgcgcgt cagagtcctc tgcgccgcag
   988201 acgcggcgct gctcaatctc tgtggacgag cacagagatg aaaaggcgag attgcaatca
   988261 agcgaccccg gttacacttg actgacttat agctctatgg ctatatgaga actgatagcc
   988321 agccgggtat gggtcctgat gtccgacgcg tacgacatgc tcttcagaac gctttccgat
   988381 cccactcggc gggctctttt cgagcggctg tgtcgcgaag gggaaaggac ggttggagct
   988441 ctcacggaca aagcgggcgt ctcgcagccg gtcgtctcca agcatctggg gctgctgaag
   988501 caggcagggc tcgtgcgcga ccgccacgaa ggccgccaca catattacag cgcgcagctc
   988561 ggcgcgctcg ctcccctggt cgactggacg cgtgagatgg ccggattctg gcagagccgc
   988621 ttcgacgatc tcgaagatct actgaaaagg atggaccaat gaacgaaacc tcgaccgaaa
   988681 cacgctccgt agtcgtcgag cgggagatcg cgcatccgcc ggagaagatc tggcgcgcgc
   988741 tcacccaacc gcacctgatg gaggagtggc tgatgaagaa cgatttcagt gccgtcgtgg
   988801 ggcaccgttt caatctgcgc ggcgagtggg gtggggtatt ggactgcgaa gttctcgtcg
   988861 tggagccgaa caagaaactg tcctacgctt ggaatttcgc ccatgaggat ccggcctatg
   988921 acttgaagag cgtggtgaca ttcacgctcg tcccaacgcg ttcagggacc cagttgcgca
   988981 tggagcaggt tggctttcgg cctgatcagc ggcaggcatt tggaggcgcc aaggctggct
   989041 ggcagcagtt cttcgaaaat ctggagcgcg tgctggcggg gatgaattga ccagcagcac
   989101 cattggggcc gcttcatgcc ctgcttgctc tatcttaagg ggagatcgta caaatgaatc
   989161 ggagcgcctg gatacgtcaa atccaccgct ggttgtccat cgtcttcacg gtaacggtca
   989221 tggccaactt cagtgccatg gcactgggag aacctcccgt ctgggtggtc tattctccac
   989281 tgcttccgct cttcctcttg ctgttcacag ggctctacat gtttgcgttg ccttattccg
   989341 caaagtggcg cggcggacgg cccacagcct gatgaggtgg agacaatggc cagcaagaca
   989401 cccggcaaaa ccgagagggc cgcaaagagg gattcttccg acggaaagcc ggtccttctt
   989461 tccggcggca atcctcagat agcaaagggc tatggcgacg cccccgtaaa ggcctatatc
   989521 gcagccatgc ccgattggaa aaaagacctt ggacgtcgcc tcgatgcgct catcgtggac
   989581 gccgttccca acgtatgtaa ggccatcaaa tggaactcgc ccttttacgg catggagaac
   989641 gacgtctggt tcctcagctt tcactgtttc acgaaatacg tcaaagtgac tttctttcgc
   989701 ggcgcatcgc tcaatcctgt cccgcccggc aagtcaaaat acccggaagt acgctacctc
   989761 gatatccatg agggtcaact cgatgaaggg caattctccg cctgggtcag gcaagcaagc
   989821 cgattgcccg gcgagcggat gtgaggggta acaaccatga agaaggccac ggccaacatg
   989881 gagaatacga tgagcggccc gaacgaagga gacgtttctc cctctcaact gatcgatgcg
   989941 cggatcagtg agttcagcga ctggcggggc gagacgctcg cccgaattcg gaaactcatc
   990001 cggcgggccg acccggaagt gatagaggaa gtgaagtgga gaggcgttcc cgtgtggtcg
   990061 catgcgggaa tgatctgcac cggcgaggtc tacaagaatg cggtgaagac cactttcgcc
   990121 aagggcgcct cgttggacga cccttcgggt cttttcaatt ccagcctcaa gggcaatacg
   990181 cggcgtgcca tcgattttca cgagggcgag gagatcgatg aagaggcgtt catcgcgctt
   990241 gtgcgtgccg ccgtggcgct gaacatgtcg gcacgcacga gcgctcgttc gcaaaagaaa
   990301 ccgaagagca cctgacaccg atggacgtcg gctcgaaaca gtgcgtttcc caaatgcgca
   990361 tttgcgaccc aatcctgcgc cgattatctc taaggcagag ctagactcgc aggaaagcag
   990421 ccatggaact cggactctat acattcgccg acgttgaccc gaatgcagcc gacaagggag
   990481 cggaggcgcg ccgtcgcctc acgaatcttc tggaggaaat cgagcttgcc gatcaggtcg
   990541 ggctcgacgt tttcggcctc ggcgagcatc accggcccga ctatgcggcg tccgcaccgg
   990601 cggtgatcct cgccgccgcc gccgcccgca ccagccgtat acggctgacg agtgcggtca
   990661 ctgtgctgag ctccgacgag cccgtgcgcg tcttccagca atttgccacg ctcgacgtgc
   990721 tttcgaacgg gcgcgccgag atcatggcag ggcgcggctc cttcatcgaa tcattcccgc
   990781 tcttcggcca gtcgctggac gactacgacc agcttttcgc cgaaaaactg gatctcctcc
   990841 tggcgttgcg cgacaatgaa agggtcacct ggtctggcgc cctcagagcg ccgatcgacg
   990901 accgcggcgt ttatccgcgc ccactgcagg acccgctgcc gctgtggatt gcggtcggcg
   990961 gaacgccgca gtcggtcgcg cgtgccggtg cgctcggcct gcccatggcg cttgcgatca
   991021 tcggaggcga accggaacgc ttcgccccgc tcttccagct ctaccgtgag gctgcgcgca
   991081 ggtcggggca ggacccgtcg aagctgaaga gcagcatcaa cgtccatggt ttcatcgccg
   991141 acaccacgca ggaggctgca gatcagtttt acggcccgca ggccgaagtg atgaaccgca
   991201 tcgggcgcga acgcggctgg ggtccaacca accgcaccca tttcgatcgg gccatcagcc
   991261 cgaccggcaa tctcttcctc ggggaccccg agacagtcgc aaggaaaatc gtcgcgcatc
   991321 agaagctctt cgacatcgat cgctttctgc tgcagatggc gattggcccg atgccgcatg
   991381 accggatttt gcgcggcatc gaactctacg gcacaaaggt cgcgccgctg gtccgcgaaa
   991441 tgctggccga gcagcacagc tcttgagttg tacacggccg ctccggtact ggaatatccg
   991501 gctcccgcac gctaaatgtg ccgcgaaagc gagacatcat gaccctcaac aacgacgacg
   991561 acctggaaag gctgaaggaa atcggccgga tttgcgccaa tgcgctccag acgatgggcg
   991621 aggcgctgga gccggggatc accacggccg agctcgacgc gatcggccgc aaggttatgg
   991681 aggaggcggg cgctcgctcc gcacctgagc tttgctatgc atttccaggg gcgacctgca
   991741 tcagcgtcaa tgaggagatc gcgcacggca tacccggtag ccgcgtgatc caggcaggcg
   991801 atctcgtcaa catcgacgtt tcggccgaga agggcggcct ctttgccgat acgggcgcat
   991861 cctttcccgt gccgccggtc actgcggcca tcgatcgtct ttgccgtgac gggaagcgcg
   991921 ctatgtgggt ggggttgaag caggtcaagc cgggccagcc gctggccgcg atcggcaatt
   991981 cgatcggtgc ctttgcgcgc aagaaccgtt actctctggt cgccaatctg gccagccacg
   992041 gtatcggccg gtcgctgcat gaggagccga gcgaaatcgc aacctggccc gacccgtctg
   992101 agcggcggcg gatggccgag ggcatggtct tcactgtcga gcccttcctg tcgatggggg
   992161 cgcagtgggc ggaaggcgga gacgacgatt ggacgctcta tagcgaaccg cgcgcgccga
   992221 ccgtgcaata cgagcatacg gtcgtcgtca cccgcagcgg gccattggtt gtgacgctgc
   992281 caggttaggg aaaataccgg gtaagcggct tggccgttcg attccattga tggatcgttg
   992341 aattttgatg atttgccgcg ctcttgctgc gatgcaataa atggacatga gcactctcca
   992401 gaatcggcag gaccgcagcg gatcagggtc gaggcactcg acaatgccga gcggtctggc
   992461 ggccaccgcg atcgccggcg cgatagccat ggcggtcgcc atgggcttcg gccggttctc
   992521 ctacacccct atcctgccgg cgatgatggc cgacaccggg atttctccgg gggatgccgg
   992581 gctgatcgcc gccgcgaatt tcattggcta tctcgcgggc gcggtgctcg ccggctatgg
   992641 ttgggcgcac ggccgcgaac gcgggctcgg ccttgcggct ctggtctcga ccaccctgct
   992701 gctcgccgcg atggggctta catcgtccgt tatcgccttt tgcatcatcc gctttctggc
   992761 aggcctggcg agcgcctttg cgatgatctt catctcggga atagtgctgg ggcaggggct
   992821 cgccgcacga tccgaacacg tgccttcagt gcatttcggc ggcgtcggtt tcggcatcgc
   992881 actctcatcg atcgtggtct gggtcgcgcc cctcgcaggc gccgcgggta tttctgcgtc
   992941 gcaagccgac tggttcgcgg gcggacttgt cgcgttggtg ggcgctgtcg cggtggccgc
   993001 gctgctgcca gcgagccgcc atgccaaaag cggcggccga ccggaggcgc gccttgtcgc
   993061 gacgcggcct ctcatagccg tgacgctcac ctatggcttt ttcggtttcg gctacgtgat
   993121 cacggcgacc tttctcgtcg ccatggcccg ggatgcaagc ggtggccaca gcgtcgagtt
   993181 cctcgcctgg ctgatcaccg gtatcagcgc ggcgctttcg atttatctct ggcgtttcgc
   993241 cgttccgcat ttcgggctcg ccggtgtcta tgcggccggc ctgctggtcg aggcggccgg
   993301 tctcgtgctg acggtttccc tgccttcgcc ctacgcgccg cttgtcggcg ggctgatgct
   993361 cggtgctacc ttcatgatga tcacggccta cggcctgcag atgggccggc agctcgcccc
   993421 cgaaagcccg cgccgcgcgc tcgccttcat gacagccgcc ttcggactcg gccagatcgt
   993481 cgggccgctc gtcgcgggat ggcttgcgga ccggaccgga agctacgctt tgccgacctt
   993541 ggtcgcagct gtcgttctgt tgatctgtgg aatcgtcgtt ctcgccgaac tgcgcaggat
   993601 aaatgccgcc ctggcgcaat gacaggcacg catcacgcct ggcaggtgat gtcggcagcc
   993661 gcatgaaata acagtaacat tcgcattccg taattgttgc gcaaggtgaa ttgccctagt
   993721 ttcggcgcat caggaggcaa gtccttgtcc tccccagaaa cgagagtgcc gtcccttgtt
   993781 ccagtccttt tttccgaagc cgaaactgtt tttcatatca tccgccgtct ggagccttct
   993841 tgccgtcctt gcatggtatg gcggaggaag ggatatcggc gcttacctcg gcttgccgcc
   993901 gctcccgcct ggacaggaac cgatcatcgg agtgtccgtc ttctggtcga caccctttct
   993961 ctggttttac gtctattacg ctgtggtcgt cgccctgttt tctgcgttct ggttcgccta
   994021 cagtccgcat cggtggcaat actggtcagt cctcggcacg gcgctcatca tattcaacac
   994081 ctatttctcg gttcaggtca gcgtcgccat caatgcgtgg tacggcccgt tctatgatct
   994141 gatccagcag gcgcttgcgc gcacagcgcc cgtgacggca ggtcagctct attcggggat
   994201 ggtcggcttc gccggcatcg ctttcgtggc ggtgacggtc ggcgttctca atctcttttt
   994261 cgtcagtcac tacatttttc gctggcgtac ggcgatgaac gaatactacg tcacccactg
   994321 gccgaggctg cgccacgtcg aaggtgcatc gcagcgtgtg caggaagaca cgatgcgttt
   994381 ttccagcacg gtggaaaggc tgggtgtcgg cctcgtcagt tcgatcatga cgctgatcgc
   994441 gtttttgccg gtgctcttca agttttccga gcaggtaaac gttctgccga tcgtcggcga
   994501 aataccgcac gccctcgtct gggcggccgt attctggtcc gttttcggca cggtttttct
   994561 ggctgcagtc ggtatcaagc tcccgggact ggaatttcgc aatcagcggg tcgaggcggc
   994621 ttatcggaag gaactggtct atggtgagga tcacgaggac cgcgccgatc cggtgacact
   994681 cgggcagctg ttcgataacg tcaggcgtaa ctatttccgc ctgtatttcc attacatgta
   994741 cttcaacatc gcccgcatct tctaccttca ggcagacaac ctgtttggta ccttcgttct
   994801 ggtgccggcg atcgtggcgg gaaagctgac gcttggcgtc atgaaccagg tcctgaacgt
   994861 cttcgagcag gtgcgcacgt cgttccagta tctcgtcaat tcctggacca cgatcgtcga
   994921 gcttctttcg atctacaaac gtctcaaagc ctttgaatcg gtgttggacg acgaaccgct
   994981 gccggaaatc gaccgccagt tcatcgacgc tggcggtaaa gaagagttgg ccttgtaacg
   995041 gcaggcatca gaaggcggag cgatccgcct tctttctcgc attctcgatc agcggcaggg
   995101 cctcggcgta gctgacgcag gcgacgtcag gcttgctgca ggtttccgac agaaagccgt
   995161 cgagggctcg ccaataggcg ccgccgttca tctcgacgaa gtggaagcca agctggaggg
   995221 gtatgcgctc gccttcgtat tctttgcgaa aggcattgcg aaacgcggca agcgttcgtt
   995281 cctcgaagcg ggcgctgtct ctgctgttct cgactcccat cgaatgacgg acgaagaggt
   995341 tgtagtccat cccgatgacc gggcggtggg aagggccttc cgggatgagc ggcagcccga
   995401 aacgtataag tccgtctgcg aagctgggcc agccgggccc cttggtgacg aggctcgcat
   995461 catagctgaa accgaatgtc ttcagtgcag gcacgaggcc gtcgctgaga gacaggtagg
   995521 gggcgcgaaa acccttgatg ccgccttgcg cgaaatcggc ccagccctcc ggctcggctt
   995581 ccggtttgcc ggccctcttc caggcgttcg ccagcgctgc gcggaacgcg gaaaactcgc
   995641 ttgcccagtc cgccttgctc cagtcctttc cgtcgaaatg gccgcaggca tggctcccga
   995701 tctcgtggcc agcgagatgc gcctgccaga catggccggc gcgcatcgcg atgtcttcac
   995761 ggctttgcgc gaacccgacg tttgagcggc ccggcttctg acccggcgcg cgataggtct
   995821 gctttccgtc agctctcgtc atcaggaagg tgcaggagag gaaataggtg aaacgcgcgc
   995881 ccgtgcgctt gcccattgtg aggcttttct gccaaagcgc attgtcgtgc gcgccatcga
   995941 acgagatgac gacgagctgc tttggcaact ggcgagccga cggcggatcg gcgagggcga
   996001 gagcgggaaa aagagcaacg gataaagcca aagaaatacg aatcatgttt caactgtgac
   996061 gattggtttc gtcgcagttc gtccgaaatt gcggcattcc tttgattggg tggaaaaaag
   996121 gcgctatcgc agatactgca tagctagctg gatcgccgaa acagacgccg tcatacggca
   996181 cttcagcggt ccgacatctc gaacaagcgg tgactcatgg ccatactcct tctgggcatc
   996241 atcatatttc tcggcatgca cctcatccgc gtggttgcgc ccggctttcg ggccggcatc
   996301 atcgaaagcc gcggcaaggg cacatggatg gggctctata cgatcgtcag cctcgtcggt
   996361 gtctgtctga tcatctacgg tttcggtcag gcgcgtggcg aaaccggggt gctatacaat
   996421 ccgccggagt ttttgcgcca tatcgccctt ctcctgatgc tcatcgcctt catcgtgctt
   996481 gctgcaggct ttctgccggc gggccgcatc gccgtggcgc tcaagcatcc gcaggtcctc
   996541 tcgatcaaga tctgggcgct cgcgcacctg cttgccaatg gcgagacgtc ctcggtgctg
   996601 ctcttcgggt cctttcttgc atgggcggtg atcctgcgca tctcgctgaa aagacgcgag
   996661 cgcgcgggcg agaaggtgct tccggtcttc aaatccgggc gcaacgatgt tctggcggtc
   996721 ctcacaggtc tcgccgcata tgtgctcttt gtctggaagc tgcatgagct cgtgatcggc
   996781 gttccgccgg tcgtcatcgg ttagagcggg atgtacgcgg cttgcccgcc cgcacccgct
   996841 tcagcgtatt agattcgttc tcccccttac aagcggcgca aaatcgggta gaacgcgcca
   996901 acttctttta gatcagggcc gggcggccgg gacgggacat ggtaaaccag gacgacagct
   996961 ttatccgcga ggtcaacgac gaactccgct cggaccagat gaaggcggtc tggacgcgct
   997021 tcggcagcat catcatcgga attgccgtgc tgatcgtgct cggcaccgtc ggcaaggtgg
   997081 gatacgacta ttggcaggag tcgtcctcgt cacaatcggg cgacaccttt cttgtcgcgc
   997141 taaatcttgc acgggagaac aagtcggacg aggcactcgc cgcgttgacc gggctggaga
   997201 aggaaggtta cggatcctat ccggttctgg cgcaactgcg cttggcgacg ttgcaggcgc
   997261 aaaaaggtga aacggacgct gcggtcaagg cattctcggg gatcggcagg gatacgcgta
   997321 tcccaacggc gcttcgcgac gcggcgcggc ttcgtgccgc ttacctcctt atcgatgcgg
   997381 gaacttacga gcaggtctcc tcggaggtcg agcaactggc cgtcccgcag aacgccatgc
   997441 gtcattccgc gcgtgaggcg ctcggtcttt cagcctataa ggccggcgac tatgccaagg
   997501 caaagagctg gtttcagcag atcgtcgacg ataccgaaag cccgcgcggg gtcatgaacc
   997561 gggcgcagat gctgctggac gtcatcgcct cgagcggtaa agcctgatgc atgtcgccca
   997621 aaagtgcgca gcggttttgg gatgaccata aaatagaaac ttaaggcgag gcccgtgagt
   997681 tgtatcgaac gcgaggcgct ttaatacgga tttcgagatg agctttacag tcgccattat
   997741 cgggcgcccc aatgtcggca aatccacctt gttcaaccgc ctggttggca agaagctggc
   997801 gcttgtcgat gacacgccgg gggttacgcg cgaccggcgt ccgggagacg ccaagctcgt
   997861 cgacctgaag ttccgcatca tcgataccgc cggtctcgag caatcctcgc ccgacagcct
   997921 tcagggccgg atgtgggcgc agaccgaggc agccattgac gaggcggatc tgtcgctctt
   997981 cgtcgtcgat gccaaggccg gtctgacacc cgccgacaag acgctcggcg agatgttacg
   998041 ccgccgtggc aagcccgtcg tcgtcgtcgc caacaagtcc gaggcgcgtg gctcggaggg
   998101 cggcttctac gacgccttca cgctcggcct tggcgaaccc tgcccaattt cggccgaaca
   998161 cggccagggg atgctcgacc tgcgcgatgc catagtcgct gctctcgggg aggagagggc
   998221 gtttccgccg gcggaggacg tggccgagac gaatgtcgat atccgcgccg acattggcag
   998281 tgagggcccc ggcgaagaag aaatcgagcc ggtctatgac gagaccaagc cgctccgcgt
   998341 ggcgatcgtc ggacgaccga acgctggaaa gtcgacgctg atcaatcgat ttctcggcga
   998401 agaccgactg ctgacgggcc ccgaagccgg cattacccgc gattccatct ccgtcgaatg
   998461 ggattggcgc ggccgcacga taaaaatgtt cgacacggcc ggaatgcgcc gaaaggcgaa
   998521 ggtccaggag aagcttgaaa agctctcggt cgcggatgcg ctgcgtgcca tccgcttcgc
   998581 cgagaccgtc gtcattgtct tcgacgccac catccccttc gagaagcagg atctccagat
   998641 cgtcgacctg gtgatccgcg aggggcgcgc ggcggtgctc gccttcaaca aatgggatct
   998701 cgtggaaaac tggcaggagc tgcttgccga cctgcgcgaa aagactgagc ggctgttgcc
   998761 gcaggcgcgg ggtatccgcg cagtgccgat ctccggccac accggctacg gtctcgatcg
   998821 gctcatgcag gcgatcatcg aaacggataa ggtctggaac cggcgcatct ctacggcgcg
   998881 tctcaatcga tggctggaat cgcagcaggt gcagcatccg ccaccggcgg tttcgggccg
   998941 ccgcctcaag ctcaaataca tgacgcaggt gaaggcccga ccacccggtt tcatgatttc
   999001 gtgcacgcgc ccggaagcgg tcccggagtc ctacacacgc tatctcatca atgggctgcg
   999061 aaacgacttc gatctggcgg gcgtgccgat ccggatccat ttccgcgcat cggagaatcc
   999121 ctacgagtcg aaagcgcgca agaaacgctg aacggtttcc agcaccggaa gaactcacgg
   999181 ttcgtttcga gccgcgacta tctttgatgc gatatcggcg ctaataaaag taaatctatg
   999241 taggaagtca gttgatttcc ttgccgccac tttgggcttg atctataact gaagccacga
   999301 tgccgaacgt aatcgagccg tggcaggatt ggcttggcag gcggggaaac ggcgcgtggc
   999361 cttgcgagaa tcgcaatatg cacgacattg atgtgtccgg ggcacaggga cgcagatcgc
   999421 gtgcacgtct cgtttgccgc gatccttctc gaaagcggtg ttcttatgct gacaaaaaaa
   999481 gggaagtacg ggctgaaggc gatggtcgac cttgcccagc ttcagccggg cgaaacggca
   999541 ttcatcacgg aaatcgctct tcgcaacaat ttgccgaaga aattcctcga cacgatcatg
   999601 ctcgaactga gaaatgctgg ctttcttcgc tcgaagaaag gccctggcgg cggctatgcg
   999661 ctggcgcggc ccgcatccga gatccgcgtc ggacaggtga tccgcacgct cgacggtccg
   999721 ctggcgccga tccgctgcgc gagccgcacg gcctatgaaa tgtgcgacga ctgttcggat
   999781 cccgagaact gtcacgtgcg ccgttcgatg atcgtggtgc gcgatgctgt tgcaaacatt
   999841 ctcgacaaca tgacgctcgc gcaatttgcg gcaagcgaga aagatgcagc cgatgttgtg
   999901 ctggctccgc tccgcagcga agctggttga cggctgcgag ccatgcagtc ggtgagacat
   999961 ggcatcgccg acccagcaaa cgccctcaca atgatccgtc gcgcggtcgg acgccgttaa
  1000021 ggtgatagtt gcccacgagg tgatgcttcc ggcgaagcgg gtcctgtgac gcgtgggcgc
  1000081 gggcattgcg ccaatagcga tccagatttt gggagacctt tgtggaggcg gcgccggcga
  1000141 ggtcgaaaag tgtgttggat gcctccagtg cggcctcggc ggcaagaact ttggcggcgg
  1000201 tgaccgtgat gctcgcctcg gctgcgtgcg cttctgtcgg gtctacctga gccgtatcga
  1000261 ccttaagtcc ggcatattcg atgagcgcgg tggccgcctc gaggcgtatt gcgacttcgc
  1000321 cgatcttggc gatcgccaaa gcatcctccg atgaatcggc gccgtttcgc acgtattcga
  1000381 gggtttcgcg gaatgcggcg cgcgctatgc cgagatcaac gccggcattg atgatctggc
  1000441 cgacggaacc gatcgttgtc tgtcgaccga aagcgcggtg atacggcacg accgagctgc
  1000501 gatccacatg gatgttctcg agaatggctg tgccgctgcc attgacgcgc tgaccgaagc
  1000561 tgtcccaatc atcgatgatc cggacgcctt ccgttgtgcg cgggacaaag gatagggtca
  1000621 tgagctcggt cgcgtccaga gccgagatcg cgatccagtc ggcgaagagg atgccggtca
  1000681 gatattcttt ccgtccgttg atgcggtagc cggcgccgtc cccgattatc cgggttatcg
  1000741 ggctaccgat tgttttttcg ctgctttccg aaattgcgct gctgaagcgg tcgccggccc
  1000801 gggcacgtcc gaagaagaat tgcttttgct cttctgtggc atactggcgc agtgcttcca
  1000861 gggcatgaaa atggccttgc gggatctggc cgatggagct gtcggcctcg gacaggattg
  1000921 ccgtcacctc ggccaggacg acgtttgaga cgtcgattcc ctcgtattcc gagggaatgc
  1000981 tgatcgccag cagtcctgac tgtgccagct ggtcgagttc gtcatggggg aggatgcgtt
  1001041 caagatcgcg ctcgctggcg cgctcggcaa atcggaatgc caagtctttt gctaccgtca
  1001101 gagcctcttc ctcgctctct atgtggcggg gcgcaggtct ggtctttccg gcgaattgcg
  1001161 agatgctgcc catctttgtc cctccaagga ccattggcgg ttcgctcact tcgaggctgc
  1001221 ggcggattgc ctgttcgcgt tcacgggttc catggattcg cgctctgccg tgttgcagtc
  1001281 ctcttagtat ggagcaggcg cagatttctt ccagccccag aggcaggtcg atttcatggc
  1001341 tttatgccgg ctggacgcaa cgcccgtacc cacgaaaaca ggctggaata tcagggcctt
  1001401 agccgcagtg gctataacct gttccaggcg gctcccacaa aagcgcttgc cgtcggcgaa
  1001461 ctttgcaata gaataccaaa cttgtagatt attccgcaac aggatgaccg ttagccgaaa
  1001521 ggttgttgca tacggccgga gaagcggaag tatctcgccc gatgcgggaa ggaggcgatg
  1001581 ggctatagct ggcgcgtcgt tccgaatggt cccgagcggc gagtggcata cgacccggca
  1001641 aattcgacat agctttctgt gtgtctcgaa gccctgctca agagttgccc cggtcacgga
  1001701 gcgacagcca gctcgcgaaa ggagctcaca tgaccgttcg tggattgttt gcccgcaggt
  1001761 cagcaatggc cgccttgtcg aagccggaaa tcgcgatcgt tggccgcggt ttttcgggca
  1001821 tcatgatggc gatcgcgttg atgaaatcga tgcgggtatc tttccacctc accatgtatg
  1001881 atccgcatcc atcgatcagc gggggccagg tattttccgc cgctcagcgc tgcgagatac
  1001941 tcaacagccg cgtccgcgat ctttcggtcg cggccggcca gccggatgat ttcaacgatt
  1002001 ggctctgcgc caatgatgag ttccgaacgg cggttccggc ggccattccc ggcttccggc
  1002061 agattttcgt gccgaaaggc atcttcagcg attacgtgca ccagcgcttc tccgaggcgc
  1002121 ttgcccggcg ctccgacatc acggtgaggt tctcacacga gccggtcaca ggcctgcgaa
  1002181 agctcgcaag tggtcgcttc agccttgtgc ggcacggtgg caacgacgag agcgacattg
  1002241 tcatcctcgc tacgggcttc ggcatgcgcc cgcgggacct cgaggtttcc gaggaggagc
  1002301 ggccgcttgt gcgcactcgg cgcctcgtcg atccacgcca cgcggtgctg ctcggtagcg
  1002361 ggatacgtgt ggtcgaccag ttgttccaga tgcgcgacaa cggctatgcg ggaaaggtca
  1002421 cgctcatttc gcggcacggt ttcctgccgc aggcgcacac gcagcgcgcg gcatcgccga
  1002481 gctttcccgt cgatccgctg ccgcaaggcc tgggccgtat cgtgcgcttc gtgcgtcagg
  1002541 cctgcgccga ggccgaagcg aacgggcagg gatggcaatc tgcgatgaac ggcctccgcc
  1002601 gccgcgctcg ctctctctgg caatcgctct ccgcacagga gaagcggcag ttcaaccgtc
  1002661 acctgcgtgc aatttacgac agccacagga accgcctgcc agcggccgtt cacgcgcggc
  1002721 tgcagcagga acttggcgag ggtcggaccg tgcttcgccg cggccgggcg ggtcgacgcc
  1002781 tgcccgaagg tatcctcgtg cgatgggccg gccaggatac cgaggaactg ctgagggctg
  1002841 atcaggtgat cgaatgtcgc tgttcagctc cggacctcgg aacgccgttg cttcggagcc
  1002901 ttattgcggg cgggcttgcc caaccagacg aactcgagct cggcattgct gtcgccccga
  1002961 cgggcgaagt cttgagctcg agcggacaca cgccgaacct cttcgccatc ggtccgttgg
  1003021 gattgggaag ccttcccgac atcgacctcg taccggaaat cgtcacgcag acctatgcgg
  1003081 catcacggct gatagcgaca ggaaagcgca tgacgctgaa agctggatag acgagacacg
  1003141 ggccaactgt tcgttcccac cttttattgc gggttcgcct tgaaacggcg ggcaggagaa
  1003201 ttcagaggtc aacgacgaca cgatcgccgc tgcgcagcag gtcttcgata tgatggattc
  1003261 cttcggccag aacgccccac gccctaccgt cgcgatcatc ggcggcggct tcaccggagc
  1003321 catggttgcg atgcaccttg cgcgcgatcg cgccatggac ggttggcaga ttgccgtctt
  1003381 cgagccgcgg gtgcggctgg gatgcggcct tgcctatgat accgcggagc ccgcgcatcg
  1003441 cgtcaatgtc ccggctgcgc gtatgagcat cgatccggat gaccccgacg acttcgcacg
  1003501 ctggctcgca cttcagagtg agctgcgcga cgatcccgag gtgcttgccg gcgatggaca
  1003561 tctctatcct cgccggcagc ttttcgggcg ctacgttgcc gaggcggtcg taccgttcgt
  1003621 ccggagcggg cgcatcgtgc atcaccggga aagggtgatc gccgtagagc gtgagggagc
  1003681 agcctgggcg gtccgcggcg agggcggcac gctaaaccgc gccgacgcgc tggtggtggc
  1003741 gacgacgcat ccggctccgg aggcgcccgc aggcttcggc gctgtactga ccggtcaccc
  1003801 ccgctacgtg ccggattcga ccgagccggg cgcgctcgac aaaatccgga cggatgaccg
  1003861 cgtactgatc atcggtaccg gactgacctc ggccgacgtg atcgctacgc tgcgcacgcg
  1003921 cgggcataag ggaccgatca ccgccttttc ccggcggggc ctacgctcgc gcggacatgc
  1003981 cgacagggcg caggacccct ttggcgactt cgtcgcgccg ccttggagat cagcagcgga
  1004041 gctcctcgct caggtgcgcc ggacgatatc agatgcggag gcggaaggct tcacatggca
  1004101 tgcggttctc gatgcgctca gggcacaggg cggcgagata tggcgcaatt tgccggtaga
  1004161 cgagcggcgc cggcttgtcc ggcacgcgcg gcctttctgg gatgtgcacc gttttcgcgt
  1004221 ggcgccgcaa atcgatgcga tcgtgagcac aggtctaaag gatggcgata tccgcgtccg
  1004281 cgccggttct atcgcccatt tggcgcgcgc tggcgagaat gtcgcggtca ccttccgggg
  1004341 ccggcgggct ggaggaacgg aagagtggaa attcgacgcc gtcgtgatca ccacgggtcc
  1004401 ggcccaccgg tcgatcctgc aaagtcagcc ctggctggag tcgctcggag ccgccggtta
  1004461 tctgcgcccc gacacggtcg gactggggct cgcctgcagc gaagccagta gggcgctcga
  1004521 cggcgagggc gaggaggtgg acgatctatt cgtcgccggt cctctcgccc gcggcacctt
  1004581 tggcgaactc atgggtctgc cgcaggtcaa cgaccacgcc attttcgtgg cggcgcaaat
  1004641 tgcggcgctg gcgcaggcgc gccgagcaga aagcgttcgc tccaggcgcg aggaagccgc
  1004701 aacataggtg cccccaggcg cggagctcct gcgcgacgag gctccctggc aaagccgcta
  1004761 caacttctgc ggcagctttg gcgggccatc gcttacgttt tttgccgttc tgccttatat
  1004821 tgggatgcgt cgatttctcg acgagaggta gagctggcta agtggtctgc ggctttcgcc
  1004881 tctgcttcag atgagaagcc acgaggtacg gcgaatggct cgcatcctct tcctgttgtt
  1004941 tagcctcctg tcggccttca tgcttcctgt ctcgccggct ccggcagccg agcggaaagc
  1005001 aatcgtcctg cacgtaaacg gcgccatcag tccggccacg gcggaatatg taacgcgcgg
  1005061 cctgcggcgg gccagggacc gcggtgtcgc gctggtggtc ctgcagatgg atacgcccgg
  1005121 cggactggat acgtcgatgc gcgaaatcat acgcgccatc ctcgattcac ccgtgccggt
  1005181 cgcgagtttc gtcgcgccca gcggagcgcg ggcggcaagc gccggcacct atattcttta
  1005241 tgcgagccac atcgcggcca tggcgcccgg aaccaatctg ggcgccgcca cgccgatcgc
  1005301 catcggcggt ggactttttg gcgatgacga gcgggacggc gaggaaacgc cgggcgaacc
  1005361 ggacaagcag gaaccccgca agccggccga tgccggcgag gcgaaactta tcaacgatgc
  1005421 aatcgcttat atccgcggcc ttgcggagtt gcgcggtcgc aatatcgact gggcggagcg
  1005481 cgccgtgcgc gaggctgcca gcctttcctc ggccgcagcc gcgcgcgaac aggtcatcga
  1005541 cttcaccgcg atcaacctca atgacctcct caagcaggca cacggtcgct ccgttcgcat
  1005601 cggtcaatcc gacgtccggc tcgatactgc agggctcttc atcgaggact tgccgcccga
  1005661 ttggcgcacg cagctcttat cggtgatcac caatcccaat gtcgctctcc ttctgatgat
  1005721 ggtcggcatc tatgggctca tcttcgagtt tctctcaccc ggcaccgttg tgcccgggac
  1005781 cattggcggc ataagtctcc tgctcggtct ctacgccctg gcggtgctgc ctgtgagcta
  1005841 tgccggcgtt gccctcatcc tgctcggagc cgggctgctg gtcgcggaag cgcatgcgcc
  1005901 gtctttcggc gttctcggcc ttggcagcgc cgtcgcgctg gtgctcggtg ccgcaattct
  1005961 tttcgacacg gacgtaccgg gactgcaggt gtcctggccg gttctgagcg gcatcgggtt
  1006021 cgcaagcctg gctttcggcc tgctggtcgc ccgtctcgct cttctctcga gccgacacaa
  1006081 gatcctcacc ggagcggagg agatgatcgg catctccgga aaggtcgaca gctgggaggg
  1006141 agcgggcggc tacgtgattg cccacggcga gcggtggagc gcagtcagca atgaaccgct
  1006201 cggtccggga gaggacgtca tggtcgtcgg ccgtcagagt ttgacgctgg aggtggcgcg
  1006261 caagccaact tgagtcggat gagcaaaact tcgcggtttt ccgcccgcat accgcgtaaa
  1006321 cgtcttattc gacctcggat gcaaggagat cgcacatgac ctggcttgga aatcttgcgc
  1006381 ccttcgccgc cgcgctcctg ttcctgttga tcatcgtcgc ctatgcgatc aggatactca
  1006441 gggaatatga gcgcggcgtc atcttcacgc tcggccgctt cacgggcgtc aaggggccgg
  1006501 ggctcatcct gatcctgccc tatgtacagc agatggtacg cgtcgacctc aggacccgcg
  1006561 ttctcgacgt gccgagccag gatgtcatct cgcgcgacaa tgtttcggtg cgggtcagcg
  1006621 cggtgatcta tttccgggtc atagacgcgg agaagtcgac gattcaagtc gaggatttca
  1006681 tgacggcgac aagccagctt gcgcagacga cgctcaggtc agtgctgggc aagcacgatc
  1006741 tggacgagat gctggcggaa cgtgaccggt tgaacgagga cattcagaag atcctggacg
  1006801 tgcagaccga cgcatggggc atcaaggtcg cgacggtcga gatcaaacat gtggacatca
  1006861 acgaatcgat gatccgtgcg atcgcccggc aggccgaggc cgagcgcgaa agacgcgcca
  1006921 aggtcatcaa cgcggagggc gaacagcagg cggccacaaa actgctggaa gcggccgaga
  1006981 tactggcccg gaaacctcag gccatgcaat tgcgctatct cagcaccttg aatgtcatcg
  1007041 ctgccgaaaa gaactcgacg atcatcttcc cgttcccgat ggagatcgcc gacatgctgg
  1007101 cgacaaagaa ggagggttcc tcctaaagcg cttccaggaa aagtgtgcag cggttttccg
  1007161 cccggaaggg cgtgatttaa aaagcgcttg caggaaaagt gtgcagcggt tttccctccg
  1007221 gatgtgggaa ttgtaagcga caggtcacaa atgccgaaga gaagcgcggg tattctgctc
  1007281 tacagatatg aggcgggcaa cctcctggtt ctgctcgtcc acccaggggg acccttctgg
  1007341 agcaacaggg acgtcggcgc ctggtcgatc ccgaaaggcg agtatgatgc cgccgaagaa
  1007401 cccgaggcgg ccgcgcggcg ggaattcctc gaggagaccg ggatcgcaat cggcggtcct
  1007461 ctggagttcc ttggtgaaga gcgccagaag agtggcaagc tcgttacggc ttacgcgcat
  1007521 gagagtgaat tcgacgtaga cagcctgcgc agcaacgtgt tcgaaacaga gtggccgccg
  1007581 cgaagcgggc aaatgcagtc cttccccgaa gtcgaccgcg ctgcatggtt cacgcctgca
  1007641 gaggcgcgca gaaggataaa cgcctcgcag cggccattca tcgatcgtct ggaggcgttg
  1007701 cgaagccgcc gggcgccctg acgcgcagcg ttcgggcgat tgcgctccgc cgagctgcat
  1007761 cagtggttgg tggtgtgcag tcccggctgg accggtctcc cgctgaatgc tagctcgccc
  1007821 atatcggagc ccatgtcggg gcggtaagcc tcggcttcga cgccaggtac gatctgcaca
  1007881 ggcagtccga ggcgttcgaa tgccgcgaat tcctcgtcga ctgccatcgg attcccggac
  1007941 cggaggcgca ccacgttctt tcccttccgg accagcgccg caatgtctcc ctggacgaga
  1008001 atcgcgttgc tgctgctgcg atctttgtcg ctgcctgcga cagggacgcg cctcgcctcc
  1008061 cggcgcgcca gttcaaggac ctcgtcctga atgcattcgt caaagagtat cacgtcggca
  1008121 gcctgcagcg cgcggaccgc cttcaaggtg aggagttccg cgtcgccggg tcctgccccc
  1008181 acgatggtga cgcggccgat ggcggagggg cgcgtgacct gacgatccgc ctccgccatc
  1008241 agccgcatct ccacaccctg ctccggtttg ccgagaaagg cccggtcgac gaaacgttcc
  1008301 cagaagatgc ggcgggcagc cccagggctc agacgggcat tcacgcgatc gcggatagcc
  1008361 tgggcaatcg acgcccaatg cttgagcgct ggcggcagca gggcctcgat ccgtctgcgg
  1008421 atcgcctgcg ccagtatcgg cgccgcgcca tcggtcgaga tcgcgacgat cacgggcgag
  1008481 cggttcacga tcgatccgaa ctgaaattcg cagaaggccg gcttgtcgat gacgttgacg
  1008541 ggcacgcctg cggttcgtgc ggcatggaag aacgcttccg cctcggattg ctcgtcacaa
  1008601 tcggcaatgg cgattgccgc gtctcgaaat gcgtctgcat gccaggcctt atcgtggtga
  1008661 acgaaacggc cgagctcatg cgcggctcca cgggcgagga cgtcgaggaa gagaccgctc
  1008721 agtatcgcgc gcggcgcata gacgtgaact tccgcaccgc aggccgacag cagttcggct
  1008781 ttccaggcgg ctgcatcgct gccgccggcg acgagcaccc gtttgctctt cagaggccag
  1008841 aaaagcggca gcgtcgcgag cgcggccacg cgctctcgct ttgcgggccg ctcactctgc
  1008901 tgcgacggtg aggcaagcat ttatgattcc cctgatttcg gcacggcagg agccgcaatt
  1008961 ggtgccggcg ctgagctttt cgcccaccgc ttcgacgcta tggcatccga cgcgcacggc
  1009021 ggcggtgatc tggttgacgc cgacactgaa acacgagcag acggtcgcgc ctgggtcggg
  1009081 ggtgtcggca cccgggcggc cggcgaccac tgcgaaacgt ttgccaagat tgtgatgcga
  1009141 cgcacggagc tgcgataccg cccagttgcg cgcgacggcg acaggctgcg gggaaagaaa
  1009201 caaggtggcc agcagccggt cctcttcgaa aaaggcgagg cgaagctcgc ctgaggtgcg
  1009261 gtccgtatag ccgatcggct ctatctcgga agcgatcccg aacgtcttcc ggcaccagtc
  1009321 ggtccagtca atttcctttt cggcgaaagc gagttccatc cgccatccgc cttcggccct
  1009381 ggcgatcgcc caataggcgg cgtcgagctc cgcaggcttg tgcgccgaga ccgcgaagcc
  1009441 atagaccgct gctgcaaggc gacccgcacg aaccgtcata tgcttcgatg ccggctggcc
  1009501 ggaaacaggg tcggtgatgg gcgcaaccag tgcatcgatc cgcgccctgg aagcgaattg
  1009561 atcgttccaa tgcatcggca cgaatagatt gccttccgcc tgtcggtcgg tgacgagtgc
  1009621 ccggacaatt gccgccccat gcggactttc caaggtcacg aggtcggcgc cgctgacgcc
  1009681 gatcgcctgt gcgtcgcgcg ggtgaatctc gacgaagggc tcggccagat ggccggagag
  1009741 ccgcgcgctc ctgccggtgc gcgtcatcgt gtgccaatgg tcgcgcacgc ggccggtatt
  1009801 gagcgtgaac gggaaggccg cgtcgcggcg tctcggcccg ggcacctcga tggcaacgaa
  1009861 gcgggcgcgg ccatccggat ggaagtaccg gccgtccgcg aaaaagcgcc tttgctgtgg
  1009921 cgtgctgccc ctggtctgcg gccactgaaa aggtttcagc ccgtcataag cggtgccgcc
  1009981 gatctccgca tgggcgctga tgtcgaaatc gcggcgcccg ttgttctcga aacccgaaag
  1010041 cgccgcatgc tcagcgaaga tctcggcctg tgaattgtag gcgaatgctg gggcgaagcc
  1010101 catgcgttta ccgacttcgg cgagttgcca ccaatcgggc cgcgcctccc cggggcctcg
  1010161 cagaaaggca cgctggcgcg agatgcaccg ctcggaattg gtgacggtgc catccttctc
  1010221 gccccaaccc agcgagggca gaagcacgtg ggcgtggcgg gccgtgtcgg tatctctcac
  1010281 gatgtcggag acgacgacga aggggcaggc cttgatcgcc gcttcgacgg catcggcatc
  1010341 cggcatcgag acgacgggat tggttgccat gatccacaag gccttgatcc gcccgtccgc
  1010401 aacggcgcgg aacatgtcca ccgccttgag gccgggcttg ttcgccactg ccggcgcgcc
  1010461 ccagaaacgg cgcacctgat cacggtggag cgatttctcg atatccatat gggccgcaag
  1010521 catgtttgcc agccctccga cctcccgccc gcccatggca tttggctgtc cggtcaggga
  1010581 aaacggcccc atgcccggcc ggccgatgcg tccggtcgca agatggcaat tgatgatggc
  1010641 atttaccttg tcggtaccgg cggcagactg gttgacgccc tggctgtagc aggtcacgac
  1010701 gttttcagtc gtctcgaaga gccggtagaa cgcgcgaagc tgcgcctgcg tcaggccggt
  1010761 cgcgttggaa actgccggaa gatcgagcct ggatgccacc gccacggcct cgtcgaaacc
  1010821 gctcgtgcac ttcgagacat agttccggtc gatcacgccg ctggcggcga gatgggcaag
  1010881 caggccgttg aagagggcga cgtcgccgtc cggcgagatc gccaggtgca tgtcggcgat
  1010941 gtcggcagtc atggtgcggc gtggatcgat gacgacgatc ttcatctcag gtcggttcgc
  1011001 cttggcagct gaaaggcgct gataaagcac cggatggcac caggccagat tggaacccgt
  1011061 caggactacg agttcggcga gttccaggtc ctcgtaaacg cccggcaccg tatccgagcc
  1011121 gaaggcgcgg cggtggcccg ctacggagga ggacatgcaa agccgagaat tggtgtcgat
  1011181 gtttgctgag ccgatgaaac ccttcatcaa cttgttggcg atgtaatagt cctccgtcag
  1011241 caactgtccc gagacgtaga aggcaaccga atcgggaccg tgctcggcga tagcatgcga
  1011301 aaagcgttcg gcaacgaggt cgagcgcctc gctccagcct gcgcgacggc cgccgatttc
  1011361 cggatgaagg aggcggccgt cgagatcgag cgtttctgcg agcgccgatc ctttcgaaca
  1011421 gagcctgccg aaattggcag gatgctccgg gtctcccttt acgctcacgg cgccgtcatc
  1011481 acccagacgg gcaatgacgc cgcagccgac tccgcaatag gggcaggtgg tcttgacctc
  1011541 gtgcgccatg cctattccgc cgccgccagt gcaaggctct caagcgcaac atagagggcg
  1011601 ccgttgtcgt ttttcacggg aatcgtgcgc acctcgccct cgtccgcgcc cagtgccttg
  1011661 ccggtttcga gcgagatcac ccagttgtgc aacggacaag tgacggccgt tccgtgaacg
  1011721 ataccctggg agagcggtcc tcccttgtgc gggcaatggt cttcgattgc gaatacctcg
  1011781 ttctcggcag tgcggaagac ggcgatcttg ccggtgggcg tcctgatgca gcgggcgccg
  1011841 cgcaacggga tgtcgttgat atcgccaatt gctgtccagt tcgtcgtcat cgcatcactc
  1011901 cgctgcctga ttgaagccga ccgtcgccat cggccggaac tcgtgcttgt ccttgccgga
  1011961 gacgcgctct gaccaagggt cgacctgagc gaatttctgg ctgaagacga agcggtcgaa
  1012021 ataggccttg cgcctttccg catcgcccat gatctgccgg cggatctcgt cgaggccgac
  1012081 gcgctttgcc catttgtaga tgcgctcgag atagcgggcc tgctcacgat acatctgcgt
  1012141 cagcgcgacg atatgttcga gcgcctcgtc ctcggttttg accagcccca ggacttcggt
  1012201 tccctttatg tcgagaccgg cggcacctgc gaagtgaatc tcgtagccgg agtcgacgca
  1012261 gatgacgccg atatccttgc aggtcgcctc cgcgcaattg cgggggcagc cggagaccgc
  1012321 catcttcagc ttcgccgggg tccaggagcc ccacatgaat ttctcgatgc ggatgccaag
  1012381 cccggtcgaa ttctgagtgc cgaagcggca ccaatcggag ccgacacagg tcttcacggt
  1012441 tctgagcccc ttggcgtaag cctgcccgga gacgaagccc gctttgttga ggtctgccca
  1012501 aacggcgggc aggtcctcct tctcgatgcc aagcagatcg atgcgctggc cgccggtcac
  1012561 ctttacaagc ggcacgttga acttgtctgc gacgtcggcg atcgcccgaa gctccctgga
  1012621 attggtgacg ccgccccaca tgcggggtac aacggaatag gtgccgtcct tctggatatt
  1012681 ggcgtgaacg cgttcattga tgaagcgcga ctggtagtcg tcggcatatt catccggcca
  1012741 atcgcagacg aggtagtaat tgagggccgg acgacacttt gcgcagccgc aggaggtctt
  1012801 ccattcgagt tcctgcatga cggcggggat cgtcttcagc ttcttcgcct tgatcaagcg
  1012861 ccgcacgtcg tcatggccga gatcggtgca gttgcacatc ggctgtacag cggccgggtt
  1012921 gtagctgtca ccaagcgtca gcgacatgat ctgttcgacg aggcccgtac aggagccgca
  1012981 ggaggcggac gccttggtgt gggcacgtac gtcgtcgagc gaggtcagcc ccttggaggt
  1013041 gatagccccg acgatcttgc ccttgcacac gccgttgcag ccgcagattt ccgcatcatc
  1013101 cggcaaggct gcaacggccg ccatagggtc cagcggagat cctccctggt aggcctggcc
  1013161 gaaaatcagt gtgtcacgca actcgcaaat atcggtgccg cgcttcaaga ggtcattgaa
  1013221 ccaggcaccg tcaccggtat cgccataaag cactgcgccg acgatccggt tctccttgag
  1013281 aaccagccgc ttgtagatgc cggcggtggc atcgcgtagc acgatttctt cacgtccgtc
  1013341 gccatcggcg aagtcgccca cggaatagag gttgatcccc gtgaccttca gtttcgtcgg
  1013401 ggtgtcggag tgagcgaagg cagcgcgacg gtcgcctgcg aggtgagacg cggcgacgcg
  1013461 tgccatctcg tagagtggcg cgacgagacc gtagaccatg ccgccgactt cggcacactc
  1013521 gcccagcgcc atgatgttcc cgtcggacgt ctgcattccg gcatcgacga cgatgccgcg
  1013581 gttgacggcg agcccggcct ccttggcaag gcctgcattc ggacggatac cgacggccat
  1013641 cacgaccagc gtcgccggaa tgatccggcc gtcctcgagt tcgatgccct cgactttctc
  1013701 ctcgcccaga atgcgtttgg tgttggcctt ggtcaggacc ttgataccgc gctcctcgac
  1013761 cgccttctgc aggagataac ccgcggcggg gtcgagctgg cgctccatca gcgtcggcat
  1013821 gacgtgcaga acggtgacgt ccatgccgcg cgcctgaagg ccggcggccg cctcaagtcc
  1013881 aagcaggccg ccgccgatga ccacggcttt ttcgcgcgat tgcgccgcga gcagcatcgc
  1013941 ttggacatcg tcgagatcgc gataggtgat gacgccgcgc aggtccttgc ccggcacggg
  1014001 gatgatgaag ggcacggaac cggtggcgat caccagcttg tcgtagcttt cggtgacgcc
  1014061 gtggtcggag gttacggttt tcgcctcccg atcaatcgca acgatcttgt gccccttgta
  1014121 tagggtgatc ccgtgcttga tgtaccatcc gtcgccatgg atgatgatct cttcgtagtc
  1014181 cttttcaccg gatagtaccg gagagagcat gatgcggtcg taattgacgc gcggctcggc
  1014241 gttgaagatg gtcacggcgt agcgcccggg cgccttttcg aagagctctt ccagcatccg
  1014301 gcccggagcc atgccgttgc cgacgacgac gagtttttcg agtgcagttt cagtcatgtg
  1014361 gtcactccgc agcttcgacg aagcaggcgc tcgtcgagga ttgagcaggc ttcgcagcat
  1014421 caggtaggtt cggtttcgtt gccggcggga accggcataa aaaaacgccg ctcggaaatc
  1014481 gcgctccgcg gggaaaccct tacggaggca aagaccttgc gacgtcggtg tctttggcag
  1014541 gcgaatgcgg cgcctgggct cgcttcgatc gccgttgatg gaagcaattt acgaaaagca
  1014601 aatgccgtgc caagcgattg tcgtttgcct atggcgttga aaagtctggc aaagcgtaga
  1014661 gagtggccct tggctaaaag caaaccgtct ggtttaaaag taggccgttt gcacttagtg
  1014721 atgaattttt gtgccactgc gcatggttcc tcgggtcaag cccgaggatg acaggtaggg
  1014781 acgtcgtgaa aatgtctcac gtgcgactgc cctcgaccgc gcaatgcaga ccatcgacgg
  1014841 ctcggcatac tctgcgtcat cgggcgcatt cgtgcgctaa ctctgccgcc gtcatcctcg
  1014901 ggcttgaacc cgaggatcca gccacgagcg tcgtttctgc atggtggcta cgtcgaaaag
  1014961 acgaatccac actggcggga tttgtgtttc gagctttgga gccttgctgg tggagggccc
  1015021 agcgctcaga cgtcatcgac cggggtctgg accccgtcct ttccaaagac ggtaaaggac
  1015081 ttgatgtaat cttcgatcct gccgggatcg aagacatggc cgtcaatgaa gcggtcgccg
  1015141 tccgttgctc cttcgaggct gccgctgtcc gcgtcagccg gtaacgcgtc cttgccgagc
  1015201 gctccccggt agaggtccgg ccgataggcc gagacgctcg cttcgaagcc ctctcgggac
  1015261 aaggtcgtct gcccccagcg caccatttga ctgtagatcc agagcgcctg gctggggcgc
  1015321 gggaaattgg caaagccggc gtggaagacg aaatagttct cgacgacgcg gcgatttccc
  1015381 tcggggtcga tcgtgaattc gcccgcaagt acccgtcgga ttatatcgac cggcgcgccc
  1015441 aggtggcgat cctcggccaa gacctcggcg aggcgggcgc ggttctctgg aacgtccgac
  1015501 cagcgggccg ctcggtcgag cgcaacgatc aggcgcgaaa ctgtgtccgg cttcgcctcg
  1015561 gcccattcgg ggcgcatgcc gatgaccttt tccggtgccg atggccagat gtcctgcttc
  1015621 gtcgcgacga tgcggccgac gccgcgttcc gatgcgatca tgttccaagg tgcgccgacg
  1015681 cagaagccgt cgatcgcgcc cgcggacagg gcgtcggagg tcatcggtgg ggggacaacg
  1015741 accagcttga catcgcgatc gggatcgatg ccgcctgccg caagccagta gcggagttcg
  1015801 taattgtgcg acgagaacgg gtaggtgacg ccgagcgtca gcggcggctt gccggctgcc
  1015861 gccgcgctgc ggacgaccgc ctccagggcc cgggcgttcc tcaacggatc cgcggctcct
  1015921 ccgagccttc cttcctcttc cataaggccg tagatgcgcg tcgacagagt gatggcattg
  1015981 ccgccgcgcc ccagcgaaaa aggggcaatc gtcggcgacg gatttgagcc gaggccgagc
  1016041 ctggcggcaa ccggcattgg cgagagcatg tgggcaatgt cgaactgacg gaaggcaagc
  1016101 ctgtcgcgaa cattcgccca ggagacgtcc ttgacaagct caagggtaat accctcgcgc
  1016161 tgcgcaaacc cgaattcggc ggccgcgatc agcacggctg catcgacgag cggaatgaaa
  1016221 ccggcgcgga tggtccgctg tccctcatgg cgtattcttc caggggcagg aagggcgctg
  1016281 ccggtggaga gcttaccgcc tctgaattca cttttcttcg tcaacacatt cactccgctg
  1016341 tctcctcaag gtgccgcggc tcaccggatc agcaatccgg cggcagttac gacgctttgc
  1016401 gcgatctccg caatcttctt cttttcgttc atcgcggtct gacgcagcag tgtgaaagct
  1016461 tcctcttccg aaaagccacg cattttcatg agaatgccct tggcgcgctc tacgagtttg
  1016521 cgctcctcga gcgcggattt ggcgtccgcc aattcgcgct gaagccggct gaaggccttg
  1016581 aagcggctga cggccatatc gaggatcggt ttgacgcgtt cttttctcag gccgtcgacg
  1016641 atataggcgg agacgcctgc ctcgaccgcc gcctctatgg cggccgaatc cgagcgatcc
  1016701 acgaacatcg caatcggccg gccgactgtg cgggtcaact ggaacagatg ctccatcatg
  1016761 tcccggttgg ggttctcgat gtcgatgacg atcacgtcgg gctggagcgt ctcgatgatc
  1016821 cgggcgacac catgcacctc atgaatgacg gtgacttttc cgtgcccggc ttcgcgcaag
  1016881 ccttcctcaa tgatcgaagc acggatagcg ttctcgtcaa tcacaagaat ggtgaggtcg
  1016941 aagtgggtca tgccgcatca tgatgcggcg cagcaatttt cgcaatacag gaatgcctaa
  1017001 atatcttgct ttatagcaca atgcctaata tccgtgcaaa tttaatgtgg tctggcgcaa
  1017061 attcaggcag acgtgtttgt tggcgactca atagccgaac gctctctccc agaggctcgt
  1017121 tgaacggaac tcccaatcgc gtgcagcgag ctggcgcaca tccggctgcc cagccagcac
  1017181 ctttagaagt tccaggccgt cggcccgttt ttggtccaca tagcccgttc ggagccggcc
  1017241 tatcgcgaga tcagcgttcg ccatgatggt ggcgcgcgcg gcgatcgcag caaaggttcg
  1017301 ctccttgtag aatatcaagg cagcagcctc agcaatccgc gcgcagtcct cgacggacaa
  1017361 ggattgcgca tccagaagcc ggcgaagagt gctcctgata ttgacgagcg gaagggtcag
  1017421 tggcgcatag ccgagttgct cgggggcatg gagcaatgca acgtcagaat cgtcttcgag
  1017481 ttcgcccgtg gcgtactggc gatagatctc gccgattccg accattccga aggcagcgca
  1017541 ctcggcggcg cgcagagcgc ccatgcttgc cgagccgaaa accgccacgc cctcggaaag
  1017601 ggcaaagaga atttccttgt gccagacggg agcgacatat tcgaaattgc cgtcgatgag
  1017661 accgatggcc gccgccccgt cgcgcactgc ccgaagaatg tcgccttggc cggccggcgc
  1017721 gcggatcgtc agtttgtcgc ccgtcaatcg tgcggcatcg gggaccgtcg ggccgacgaa
  1017781 aacgaccttc atctgttctc agaaacctcg ggagggggcg aatagcggag acagccggtc
  1017841 agccgccatt ctgtcgtcat ggacagcgat gcacgtcgca gccgtcagcc atggagaggt
  1017901 tccgtgtgcc gggtgccgga ttgagccggc gtctggtccg attcgggcga ttgagccatc
  1017961 gccgcgacga gggagatgat cttcttccgg agcaccgggt cggcgatttt aaggaaggcc
  1018021 cgattgagtg cgatgccctc tttcgaggct acgaaggatg agatctcctg cgattcgtga
  1018081 atgtcgccag agggcctgcc cgactgagtg cttccttctt cctgctgaaa gaaaaagctc
  1018141 ggatgcacac cgagtatatc ggcaatagcc tgtaaccggc tggcgccgat gcggtttgtg
  1018201 cctttctcgt atttctggac ttgctggaag gtgatgccca gcccgtcggc aagcttttcc
  1018261 tggctcaagc cgatcatcaa ccggcgcatg cgaacacgcg agcccacaaa ggcgtcgatc
  1018321 gggttaggat cctttttgtt catctgctaa tctccttcga gctcgattca acttatctca
  1018381 tataagtttg cttgaatgga cgccgcgatg caatcagcac gcgccgcttt ctggggcaaa
  1018441 acgcaacttt ccgagaattg ccgagttcga gtgccgactt ggggcagcac gcagcctgac
  1018501 gggagacttc agaatttcaa cccgatatcg tcaataggga caggatgaat cgaatcagtg
  1018561 agagcccgcg actatgagtg ttgagtacaa atcagaacca aatgccctac ggcgttttcc
  1018621 cggctcgatc gtcgtcatgg gggtctccgg cagcggcaaa tcgtcggtag gggaggcgat
  1018681 cgccaaggcc tgcggctatc ccttcctcga aggcgacgcg ctccatcctg cagaaaacat
  1018741 caggaaaatg tccgagggag ttccgctcac cgacgatgat cgctggccct ggctcgatgc
  1018801 gataggcgag aggctggcaa gccgggagcc ggtcgtcgtt tcttgctccg cccttaggcg
  1018861 catctacagg gataagcttc gcgaaagcgc tccaaggggc ttggccttcg tcttcctcta
  1018921 cggcagcgag gctgtgctct ccgaacggat gcagcaccgc acggggcatt tcatgccgtc
  1018981 ctcattgctt cagacgcagc ttgcgacgct cgaagatcca agaggagaag cgaaaacgat
  1019041 cgcggtggat gttgcccacc ccctcgcgga gattgtccgc gaggcgctgg aaggtctcgc
  1019101 ccgtctgtaa gttcgcgttg cgcaatggcc atgccggtct ttgcagatcg tgcttggcac
  1019161 gccggctctt tggaaggaaa ttagccgaag gcgatgctat cgttcgcggg cgcgctttgc
  1019221 tcgacaatcg ggaggtcgtg gagcgggcgc cgggaggaga cggaaatgtt cgaagctggc
  1019281 ttgaacttcg ccttcagcga ggagatcgat gcgctgcgcg agagcgtgcg ccggttcgcg
  1019341 accgagcgaa tcgcgccgct tgccgacgag gtcgaccgca aaaatgcctt tccgatgccg
  1019401 ctgtggcggg agatggggga actcggcctg ctcggcatca ccgccgacga ggcccatggc
  1019461 ggggcggggc tcggctatct tgcccattgt gtagcgatgg aagaaatcag ccgggcatcc
  1019521 gcctcggtgg gcttgagtta cggcgcccat tccaacctct gcgtcaatca gatcaaccgc
  1019581 aacggcagcc cggcacaaaa aagcacctat ctgccgaagc tcatctccgg cgagcatgtc
  1019641 ggggcgctgg ccatgtcgga gcccggctcc ggctccgatg tcgtctcgat gaagctcagg
  1019701 gccgacaagc gcggcgaccg ttatgtcctg aacggcacca agatgtggat caccaatggc
  1019761 ccggatgccg atgtcctggt cgtttacgcc aagaccgatc ctgccgccgg accgcgcggc
  1019821 atcaccgctt tccttgtcga aaacacgttt ccgggcttct cgacgggccg gaagctggac
  1019881 aagctcggca tgcgcggctc gaatacgtcg gaactcatct ttaccgattg cgaggtgccg
  1019941 caggaaaacg tgcttggagc ccttggcgaa ggcgtcaagg tgctgatgtc cggcctggat
  1020001 tatgagcgcg tcgtgctttc ggccgggcca ctcggcatca tggccgcttg cctcgatgtc
  1020061 gtcgtcccct atctccatga gcgaaagcag ttcggacaac cgatcggcga gttccagttg
  1020121 atgcagggaa agcttgccga catgtatgtt aggatgaatg ccgcgcgggc ctatgtctat
  1020181 gctgtggctg ccgcttgtga ccgcggggaa acggcccgca aggatgcggc cggctgtatt
  1020241 ctctatgcgg cggaagcggc caccgccctg gctctcgaag cgattcaggc gctcggcggc
  1020301 aatggttaca ccaatgattt tccggcaggc cgcttgttgc gcgacgccaa actctacgag
  1020361 ataggcgcgg gcacgagcga aatacgtcgt atgctgatcg gccgggagct attcgccgag
  1020421 acgaaatagg catgcggcgg cggttctgcc ggccggtaag cacaacgccg acgaagaaaa
  1020481 gggcgggggg aaatgacggt attgcgttcg catatttcgc cttcctcgga gggtttcaaa
  1020541 gcgaaccggg cggccatggc ggaggccatc gcggcgatcg aggacgcagt ccggctggct
  1020601 gcatccggcg gtggcgacaa agcgcgcgag cgacacgtca gccgtggaaa gcttctgccg
  1020661 cgggatcggg ttgccgctct cattgacccg ggcacgccat ttctggagct cggagcgacc
  1020721 gcggcgcacg agatgtataa tggtgacgcg ccggccgcgg ggttgatcac cggcatcggc
  1020781 cggatctcag gccgcgaatg catgatcgtt tgtaatgatc cgacggtcaa aggcggcacc
  1020841 tattatccga tgacggtcaa gaagcatttg cgggcccagg agatcgcggc ggaaaaccgg
  1020901 ctcccctgcg tctatctcgt cgattccggc ggggccaacc tgccgaacca ggacgaggtc
  1020961 ttcccggatc gtgatcattt cggccgcata ttctacaacc aggccaatat gtcggcggcc
  1021021 ggcattcccc agatcgcggt ggtgatgggc tcctgcacgg caggcggcgc ctatgtgccg
  1021081 gccatgtctg atgaagccat tatcgtcgaa aaacagggca ccatctttct ggcaggcccc
  1021141 ccgctggtcc gcgcagcgac cggcgaggtc gtctctgccg aagagcttgg cggcgccgat
  1021201 gtccacacgc gcctctcggg cgttgccgat caccttgcgc gcgacgatgc ccacgcgctt
  1021261 gcgctggcgc gccgcgccgt ttcggccttg aactacggga agccctggcc ggttcagcga
  1021321 atagatccgg agccgccgct ctacgatccg gaagaaatcg caggcatcgt tcccgccgac
  1021381 ctgaagacgc cctacgacat ccgtgaggtg atcgcccgac ttgtggacgg ctcccgattc
  1021441 gacgaattca aggcgcgctt cggcacaacg ctcgtttgtg gcttcgccca tgtccacggc
  1021501 attcccgtcg gcatcgtcgc caataatggc gttcttttct cggagtctgc agtcaagggg
  1021561 gcgcattttg tcgaactttg cgcgcagcgc aggattccgc tcgtttttct gcagaacatc
  1021621 accggcttca tggtgggccg caaatatgag acggagggaa ttgccaagca tggcgccaag
  1021681 ctcgtcaccg cagtcgcgac ggtgaaggtg cctaagatca cgatgctggt cggcggttcg
  1021741 ttcggggctg gcaattacgg gatgtgtggg cgtgctttct ccccgcgctt tctctggacc
  1021801 tggcccaaca gccgtatttc ggtgatgggc ggtgagcagg cggcaggcgt tctctcctcc
  1021861 gtgcgcggtg aagccctgaa gcgctcggga ttgccttgga gcgaagagga agaagcccgt
  1021921 tttcgccaac cggttctcga tcttttcgag cgccaaagcc atccgctcta cgcgtcggca
  1021981 aggctgtggg acgacggcgt gatcgatccg cgcaagagcc gcgacgtgct ggcgctttct
  1022041 ctctcggccg ctttgaacgc gccaatcgag gacacgcact tcggactgtt caggatgtaa
  1022101 cgggaggccc cgtgttgaaa cgcgacaaca tcaatgccct gaacgccccg cagccgcgcg
  1022161 gcggttactc gcaggcagtg agcattgagg atttccggcg cgtgcttttc atcagcggcc
  1022221 agattccggt gaactcggac gaggtcgtgc cggaaggttt cgaagcgcag gcgcgccagg
  1022281 tctggcggaa cgtcgatgca cagctcaagg ccgccggcat gtcgaagacc gatatcgtca
  1022341 aggtcaccac gtatctggcc gaccggcagc atgccatcgc gaaccgtgaa atccgcaacg
  1022401 attatctcgg ttctcttgcg ccggcgatga cggtcgtggt tgccggcatc ttcgattccg
  1022461 cctggctcat tgaagtcgaa gtgaccgcag cgcaatagat cggaagagaa gcgcatgttt
  1022521 tcgaagctcc tgattgccaa ccgcggtgag atcgcctgcc gcattatccg caccgcgcgc
  1022581 cgcctcggga ttcgtactgc cgccgtctac tccgacgcgg acggagacgc cctgcatgtg
  1022641 gcgctcgccg atgaggcgat ccggatcggg gcggcgcccg ccgcccagag ctatctggcg
  1022701 atcgggtcga ttgtccaggc ggcaagaagc gtgggcgccg aggccattca cccgggatac
  1022761 ggattccttt cggagaacgc cgatttcgcc gaagcggtcg gagaagcagg catggtattc
  1022821 gtcgggccgc cgcctgccgc gatccgtgcc atggggctga aggacgccgc caaggcgctg
  1022881 atggaacggg ccggagtgcc ggtcgtaccc ggctatcacg gcgaagaaca ggacgcatcc
  1022941 tttctcgccg agagggcgcg ggaaatcggt tatccggtgc tgatcaaggc gcgggcgggc
  1023001 ggcggcggta aaggcatgcg gcgcgtggag cggcaggacg atttcggctc ggcgctggag
  1023061 gcggcacgca gggaggccgc atccgccttc ggcgatggtt cggtgcttct cgagcgttat
  1023121 ttgacgaagc cgcgccacat cgaaatgcag atcttcggcg accgccaagg caacatcgtc
  1023181 caccttttcg agcgcgattg ttcgctgcaa cgcaggcacc agaaagtaat agaggaggcg
  1023241 ccggcaccgg gcatgaccgc ggaagtccgc cgcgccatgg gcgatgcggc ggtcagggcc
  1023301 gctcaggcga tcggctatgt tggtgccggt acggtggaat tcattgccga cgtgacgaac
  1023361 gggctcgagc cggaccattt ctatttcatg gagatgaaca cgcgcctgca ggtggagcat
  1023421 ccggttacgg aggcgattac cggcaccgac ctcgtggaat ggcagctgcg cgttgccgcg
  1023481 ggcgagccgt tgccaaaaaa gcaggccgac atttccatca acggctgggc tttcgaggcg
  1023541 cgtttttatg cggaggaccc ggtccgcggc tttctgccgg caaccgggcg actgacgcat
  1023601 ttgagctttc ccgaggacac cgcgcgggtc gatgccggtg tccggcaagg ggatacgata
  1023661 acgccttact acgatccgct gatcgccaag ctgatcgtgc atggacagaa ccgttcggcg
  1023721 gcgctcggaa aattgcagga tgctctcaag gagtgccgca tcggcggcac ggtcaccaat
  1023781 ctcgactttc tcatccgtct gacagaagag catgagttcc gctccggcca tccggatacg
  1023841 ggactgatcg atcgggagac cgagcggctg accgcaccgg ttgtgcccgg cgatgaggcg
  1023901 ttggctttgg ctgcaatcat ttcgacggga gcgctcgaac cggaaatgtc gaccgatcca
  1023961 tggtcctcac tcggttcctg gcagatctgg ggtgatgcgc accgcacggt ggcgatcgac
  1024021 cacgcggacg ttcgcgcaac ggttaccctg gcctcgcgcg gccgtgacca gttcgcggtg
  1024081 cgcgccggcg ggagtacact gcccgtcctt gtgctcgacc gcatcgaggg tggtgcccgg
  1024141 ctggaggtag ccggaaaaca gcgcctgatc cggtttgcgc gagatcgcga gtccatgacg
  1024201 ctctttcacc acgggcggaa tctggtgttc cacctgccag acggattggc tggcgggcag
  1024261 agcagcgagg ttgccgaaga cgagctgctt gcgccgatgc ccgggctggt gaagctggtc
  1024321 agggtcgggg ccggcgatac cgtcagcaag ggacaaccgc tcatcgtgtt ggaggcgatg
  1024381 aagatggagt tgacgctctc cgcttcgcgc gagggcacga tcgcgaatgt tcatgtcacg
  1024441 gaaggcgctc aggtcagcga gggtatggtg cttgtcactc ttatggagga ggcagcgcaa
  1024501 tgacgccgcc ggcaagggag agcgccacga tcgtcgagat ggcgccgcgc gacggcctgc
  1024561 agaacgagcc gcggctcgtg gctacggagg acaagatcag gctcgtcgat ctgctctccg
  1024621 actgcggcta cgggcgcatc gaagtgacga gtttcgtcag cccgcgctgg gtcccgcaaa
  1024681 tggccgacgc acccgccgtc atgaccggca ttcttcgtcg cgccggcacg cgctacgcgg
  1024741 ctttgacgcc gaacatgcgc ggcttcgaag cggcgcttgc ggcgcgcgcg gacgaagtag
  1024801 cggtcttcgc ttccgcgtcg gagagcttct ccgagaagaa tataaactgc tcgatcgccg
  1024861 agagcatcga gcgctttcgc ccggtcgccg aagccagccg gcgtcatggc gttcccctgc
  1024921 gaggctatgt gagctgcgtg gtcgaatgcc cctatgaggg cgcgatcgcg ccggcagcgg
  1024981 tcgcccgcgt cacacggttg ttggccgaac taggctgcta cgagatcagt ctcggagata
  1025041 cgatcggaag cggcacgccc gaatctgtcg atcgtatgct gacaacggta cgccgcgagg
  1025101 tcgatgccaa ggcacttgcc ggtcattttc acgatacatc cggccgggcg ctggagaata
  1025161 tcggggtagc actggaacac ggcctcaggg ttttcgacgc ctccgccggc gggctcggcg
  1025221 gctgtcccta tgcaccgggc gcggccggga atgtcgattc actcgaggtc cgcgcgtttc
  1025281 tcgaaacgcg gggttttaac accgggctcg accttgaaaa gctcgatcgc gcgggtgcat
  1025341 ttgcacgatc cttgaggagc gcagcatgac tttcgcaaca attcgcttcg ccgtcgatca
  1025401 gcggggcgtc gcccgggtga cgcttgcccg cccgaataag cacaacgcgc tttccgccgc
  1025461 catgatcgcc gaaatgaccg atgtcgcggg ccggctcgca acggatgcat cggtcagggc
  1025521 cgtcattctc gacgcggaag ggaagagctt ctgcgccggt gccgatctcg agtggatgcg
  1025581 tgagcagttt tcagccgatc gggcaacgcg gatcagcgaa gcgactcggc ttgcgatgat
  1025641 gctcaaggcc ctgaacggcc tgccgaagcc gctgatcgcg cgcgtgcatg gcaacgcctt
  1025701 cggcggcggc gtcgggctga tcagcgtctg cgatacggtg atctgcgcgt cgggcgcgca
  1025761 attcggtctg acagagacgc gccttgggct gatcccggcg acgatcagcc cctatgttat
  1025821 tgcacgaaca ggcgaggcaa aggctcgccc tctgttcatg tcggcgaggg tattcggcgc
  1025881 ggaggaagcg aaggtcgccg gcttcgtaac gacgatcgtc gacgacagca tgctggatgg
  1025941 tgcggtcgag gccgcggtga cggcatatct cgttgcggcg ccgggtgctg ccgggcgggc
  1026001 aaagcggctt gcgcggtcac tgggtctacc catcaccgac gccgtcatct ccgataccat
  1026061 agagcagctt gccgacgtct gggaaacgga cgaagcgcgg gagggcgtgt cctccttctt
  1026121 cgagcggagg aatccttcct ggaggcgatg agccggtctg cgcttgattt gaaggagatt
  1026181 tgagcctatt tgaaaaggaa gccgatcaat atagggtcgc attctcatga tggccgttga
  1026241 gtttcagata gccgctgcgc gtttcgggga cgatcactcc ccatttcttt cggctcgcct
  1026301 tgtcgccgat cggctgggcg tcacgcttgc cgaactcgca aagctgatcg gcgttgcccg
  1026361 gaatacgctg acggcgaaat ccggcgcccg aaaggtcgat agtgctttaa gcagggtggt
  1026421 gcgcattctg gcgatggctt ccgaaatggc gggcgacgag agccgcgccg tcatttggtt
  1026481 caagcatcag cctatccccg gctgggccgg caagacggcg ttcgatctcg tcggagaggg
  1026541 caaggccgac aaggtgctcg cctatctcga atccgttcgc gccggcgtct acgcctgacg
  1026601 ccggtggaag cgctaacgct ctggcgtgcc ttcgtaccgc gctgggcgca tatgccgctt
  1026661 tccggtgcag gtgccgcccg tttcggtggc cgctggaatc cggtcggggt acctgctctt
  1026721 tatgccgcgc gtgaactttc gaccgcctgg gcggaataca atcagggttt cgtgcagcat
  1026781 cccgcgctca tcgttcagct tgaattgcgc gatgcagttc tcgcagacct gacggatttc
  1026841 aaggttctcg cggacctgga cgtggatgag acgatccata gctgcgaatg gcgcgacatg
  1026901 ttggacaaag gcgcggtacc gcaaacgcac cagttgcgca ccgcgcttct ggcgcgtgat
  1026961 tatcacgggg tgatctaccc ctcctttatg tctcccggcg gcacctgcgt cgcgctctgg
  1027021 cgttggaacg gtgcgaaaga gccgcgcttg gatgtcattg atcccgaggg ccggctgccg
  1027081 aaatcaccgg cctcgtgggt ttgactctgg tcgcggcagc ccctcatccc cctgccggga
  1027141 ccttctcccc gcaggcgggg cgaagggact cgcggcagcc tcgtactcct ctctcgcccg
  1027201 ctcgcggggg cagctctcgg cttccacact aaaccgagcc cagaactttg ccggggttga
  1027261 ggattccgtt gggatcgaga gcgctcttta tccgccgcat gagttcgagc tccgccgggc
  1027321 tgcgggaata gtggagaaag tcgcgcttca gcaagccgat cccgtgttcg gcagacaccg
  1027381 atccgcgata ggtcccaacc agcgcgtaaa cgatatcgtc cactgcgtgg atcgtttctt
  1027441 cggtagcgcc cggatcggaa aaggcgatat ggaggttgct gtcgccgaca tggccgaaga
  1027501 aggacacatg tgcttcgggg aactttgccc gaagcgcctg gccgcattca tcggcgaagc
  1027561 ggccgatatc gccgatcgcc aggctgacat cgaagttcag gagcaggggc agccggtcga
  1027621 gcgcatgacc ctctcgaatt cgccagaagg cttgtgcctc cttctgcgat tgagcgacga
  1027681 gcgcgtctcc gatcacaccg tcctccaagg ctctcccgag aaacgcttcg aaccgctcgc
  1027741 tctccgcatc atggccttgc aaatcctgct ccacaatgac tgcgaaagcc gggcaggatt
  1027801 cgaagagcct gagcccgtcg gcctcggaat tgaaacggaa gtagctctcc cacatcgcct
  1027861 cataggcgcc gaggccgggg agctcctgct gtgcccgctt gagcagggta acgacttccg
  1027921 aatagctgtc gagcgcgcaa agtgccgtca gccggccggt tggcaaagga cgaaggcgca
  1027981 gcaccgcgcg cgtgatgatg ccgagcgtgc cttccgaacc gatgaacaac tgccggagat
  1028041 cgtagccggt gttgttcttg atcatcttgt tcattgacga gacgacggtg ccgtcggcaa
  1028101 gcacggcttc gagccccagc acgttgtccc gtgccacgcc attgcggatg acccggatgc
  1028161 cgccggcatt cgtggccagg ttgccgccga tctggcagct accccgcgca ccaagatcga
  1028221 tcggcagcag aaagcccgcg tcttcggccg cgcgctgggc gacttcgagc ggcgttcccg
  1028281 cgagcaccgt catgctcgaa gcggtcgcgt cgacctcttc aatgccggaa agtctctcca
  1028341 gcgaaacggc gatgtcgccg gcgcgcggat tggcgccgcc ggcaagcccg gtcaacccgc
  1028401 cctgcggcac cacgcactgg ccgtgcgcgt tgcagatctt gagagccacg gcgacctcgt
  1028461 cgacgcttcc cgggcgaacg accgccaggg gaagggtccg ccccgacagg ctcgcatcgc
  1028521 tgcggtaacg ctccgtgatc cggtcgccgg tgagcacggc attgccgagt gcggccatga
  1028581 gttcttcgat aacagacata ggacagttct atctcaggat ttcttcgacc ggaattgaaa
  1028641 tcctgcacaa tccagttgtc tgtaacagag aacgaacgcg ccacgggtga gggcaaaagc
  1028701 gccacgcccg tgacgaatgg cacatcgtca ggtgccggta gcttcaagct cgggcaccac
  1028761 cacttcttcc cgtgccgtta tccggcgttc ccccttttgg aacagcttcc atcgcgttgg
  1028821 ccggaaggca attcgcgtgt ggtcggcaaa ggcggcgcgt tccggcggaa gttcgatctc
  1028881 cacccgcgga tgcgtgcgtc cgagttcgag ttcgagatgc cgcgtgcctg ccacgcgtcg
  1028941 gctggccgtg accagcccgg cgaggcagcc gccgcagccg tcaataagtt cgacgtcgtg
  1029001 cggccggaaa tagagggttg ctggaccgtc cggttcgttc gcggcgcgca ggccgatcgg
  1029061 ccggtcctcg agccagatct cgccattggc aagcgtgaca tcgaggcaat tggactgtcc
  1029121 gatgaaacca tagacgaaag gcgagacagg atggtcatag atctcgtcgg gcgagccgac
  1029181 ctgctcgatc gtccccttgc tcatcaccac gacgcggtcg gcaagctcga gtgcttcctc
  1029241 ctggtcgtgg gtgacgaaga tcgtggtgtg accggtgcgg tcgtggattt cccgcaacca
  1029301 gcgccgcaat tccttgcgca cctgcgcatc gagagcgccg aagggctcgt cgagaagcag
  1029361 aacattgggt tcgacagcca tggcccgggc gagtgccacg cgctgacgct gaccgccgga
  1029421 gagctgggcc ggatagcgtt tctccaagcc ggaaagctgc acgagatcga gcagatcgag
  1029481 cgccctgcgg cggatttcag cggccggggg acgccgtttg gccgtgcgga ccttcagccc
  1029541 gaaagcgacg ttgtcgagca ctgtcatgtg ccggaaaagt gcgtaatgct ggaagacgaa
  1029601 gccgatgttc cgctcctgca cggtcttttt cgaagcgtcg tcatcaccga agaatatcgt
  1029661 gcctcccgtc gggctttcga gcccggcgac cagcctgagc agtgtggtct ttccggagcc
  1029721 tgagggaccg agcagggcta tcaattcgcc ggaacggatg tcgagggaca cgttatcgag
  1029781 cgcgggaaag cgggcgaatt ccttgcgaat gttttggacg cggacttcca tggaggtctg
  1029841 gacctttcaa tgcctgcggc ttgcagcgat ctcgtcgctg tagcggagtt caagagccgt
  1029901 tttcaaaacg agcgtcacca gcgcaaggag cgcaagcagc gccgccaccg cgaaggcggc
  1029961 tacgaaattg tattcattat agaggatttc gacctgcaac ggcatcgtgt tggtctgccc
  1030021 gcgtatatga cccgagacga ccgaaaccgc gccgaactcg cccatggcgc gggcattgca
  1030081 aagaagcacg ccatagagca gtccccattt tatgttggga agcgtgacat gccagaaggt
  1030141 ctgccagccg gtggcaccga gcgagagcgc cgcctcctca tccgccgtcc cctgttcctg
  1030201 catcagcggg atcaattctc gggcgacgaa ggggaaagtc acgaagacgg tggcgagcac
  1030261 aaggcccggc acggcgaaga gaatctggat gtcgtagctt tgcaggattg ggccgagcat
  1030321 gctctgtgag ctgaagagca gcacgaagac gaggccggaa atcacgggcg aaaccgagaa
  1030381 tggcaggtcg atcaacgtcg tcaggaacgc cttgcccttg aattcgaatt tcgcgatcgc
  1030441 ccaggcggct gccaccccga agacgagatt gagcggcacg gcgatgcccg caaccaggag
  1030501 cgtcaggcgg attgcggaaa aagtttccgg atcgcgaagc gcggcaaaga actccgccgg
  1030561 tcccttgcgg aaggcctcga tgaacaccgt agcgagcggc aggagcagga agagcaggac
  1030621 gaatccgagc gcgactgcgg tcaggatccc acgcgaaagc cgtgtctccg aggtggccgt
  1030681 cgtcaccagc gtactggaag cgtcatgcgc cataaccgta tctccgtctg ctccacgcct
  1030741 ggatcacgtt gatgaccaac agcatgagga aggacagcag gagcatcacc cctgcaatcg
  1030801 cggttgccgc cggatagttg aattcttcaa gccggatgac gatcagaagc ggtgctattt
  1030861 cggaaacgta ggggagattg ccggcgatga agattactga tccatattcg ccgacgccgc
  1030921 gggcaaaggc gagcgcgaag cctgtcaggc cggcgggcag cagaccgggc agcaagaccc
  1030981 ggctgatcgt ctggaagcgc gtggcgccca gggtagcagc cgcttcttcg acttccttgt
  1031041 ctatctcttc catgatgggc tgcactgtgc gcacgacgaa gggcaagccg acgaagatca
  1031101 gtgccaccac tatgccggcg ggcgtgaagg cgaccttgat accaagtggg gcgagtagcg
  1031161 aaccgatcca gccgttcggc gcgtaaagag ttgtcagggc gatgccggcg acagccgtcg
  1031221 gcagcgcaaa gggtagatcg accatggcgt cgatcacgcg ttttccgggg aaacggtagc
  1031281 gcacgagaac ccaggcgagg agcacgccga aaacgagatt gacgaccgcc gctatgaagg
  1031341 cggtgccgaa gctgatcgtc aatgcattga ccgtgcgctc gtcaagcgcc agttccgcga
  1031401 atttcgacca gccaaggctg ctggaccgcc aaagcagtcc ggagaggggg acgagaacga
  1031461 tgatggtgag ccatgccagc gtgacgccga gcgccaatcc gaatcccgga atgacgctcg
  1031521 gctgccgaaa tcgccaccgc gtgctagtgc gagcggccat ggctatcatt gccccggtct
  1031581 gtaaatctgg tcgaaaattc cgccatcgcc gaagaatttc ggttgagctt ccttccagcc
  1031641 gccgaagtcg ttgatcgtga ctagcttcaa ttccttgaag cgggccgtgt cctcagcgtc
  1031701 tgccgcttcc ggcttgaacg gccggtaata gtgcttggcc gcgatcttct ggccggcatc
  1031761 gctgtagaga tagtcgagat aggcttccgc caccttacgc gtgcccttgc gatcgacatt
  1031821 gccatcgacg agcgccacgg gtggttccgc cttgatcgaa atagacgggg ttactatgtc
  1031881 aaaattgtcc gggccgagct cttccagcga cagataggct tcgttttccc aggcgagcaa
  1031941 cacgtctccc aacccgcgct gaacgaaggt ggtcgtcgca ccgcgcgcgc cggtgtcgag
  1032001 aaccggaacg tgcttgaaga gttgcgtcac gtattcctgc gcctttgtgt cgtcgccgtt
  1032061 attggcagcg cgggcccagg cccaggcagc gaggaagttc cagcgagcgc cgcccgaggt
  1032121 cttcggattg ggcgtgatca cctgcacgtc ctcccggaca agatcgcccc aatccttgat
  1032181 ccccttcggg tttcccttgc ggacgaggaa gacgatcgtc gaggtgtagg gagaactgtt
  1032241 gttttccaaa cgggtcttcc aatcggcggg aatttttccg ctctctctgg cgatcgcatc
  1032301 gatgtcggct tctagtgcca gggtcaccac gtccgcctcc agcccgtcga taaccgaacg
  1032361 cgcctgcttg ccggagccgc catgcgatgt ttggatcgtc acggtttcgc cggtatcagc
  1032421 ctgccacttc tcggcaaagg ctgcattgaa ctctttataa agttcccgag tcgggtcgta
  1032481 ggacacgttc aggatcgtcg tgtccgcatg cacgaggcca accgagccaa gctgcaggct
  1032541 tccgacgacg agcgctaatt tcgctattcc ggcaagtcta ttagagctca tttcggcctc
  1032601 catccttttg ccagataaag ctaccgattt aatagattac ttcaacgcaa acttatggtg
  1032661 ctctgaaacg gtttcttgaa aagatctatc gttctgcagg ccattaaagg aatgccgtgc
  1032721 ccgactgttc cgggtctgtg acgccacacg atagcacgac atttttaaat tgcactagga
  1032781 tagtggacta ctgtccttcg tcggattcga ggctttcgtt ctctcactcc tgcttcatat
  1032841 ggcaccgttc gctgtcagag gacgcggccg cgggcgacaa ccggccatgt ccctttgggc
  1032901 gtgccatctt cgatgacgtg gaccgcgtcg accatgttgg tcacgacgca ggcgtggttc
  1032961 ggaacgatgc ggagctgttg gccgaccgta agacggatag agccgtccga gacgaggcgg
  1033021 ccatgctctt cggagagctg gtcgatccgg atgtcgtcgc gatcaagtac gtgcccgtaa
  1033081 ccggtgagac caagcaggtc cgaggtcagg accttgctgc cggcgtcgat gatcgctcga
  1033141 ttttcgcttg gaaccgagac gacggtcgcg agcactgtga gggcgcagtc atcccatgag
  1033201 gccacgccac gggcaaccag cgaccggtcg ttatagatat atgtccccgg cctgtgctcg
  1033261 cttgctaccg gggcctcggc cgcttgcatc atgccgggcg tgccgcctga cgtaacacag
  1033321 ggaacttcga ttcccctggc ctcgatgagc tgcttcgcct cgctcatgaa ggtttgaacg
  1033381 cgtgcggcgc catcggctgg cggataggtc atcaagccgc cgaagcgcag tcccggcgcc
  1033441 gcggcaatgc gcatggcgag gcgggccgcc tcggccggcg ttgcgacgcc gcaacgttcc
  1033501 gcaccggtgt tgcattccac gagcacggtc atgggcttgc ctgcatcggc aaaaaaggct
  1033561 ccgagcccgt caacgacagt cgcattgtcc gcgacgacgc tcaccgtgac cttttcactg
  1033621 agtcgtgcga gccgcgcgag cttctcctcc ccgaggaggt tgtaggtgat caggacctct
  1033681 ttaatccggg cgctgccgtc gaccatcgct tccgcctccg taaccttctg gcaggtgatg
  1033741 ccaatcgcgc ctgagtcgag ctgcagctcg gccagctgtg gaagcttatg ggtctttatg
  1033801 tgggggcgca cgcggatgcc gtggcggtcg gcataggcct gaaacgcgag gatattgcgc
  1033861 cgggcgatat cgagatcgac cagcacggcg ggtgtttcga tcggcagggt catgcaggca
  1033921 tcgctcctcg ttccgaatag atcggcggcg aatgtagccg atcctgcttg acaagtaatg
  1033981 gctcagggcc tttgatgggt caatccggta tttaggactt atgtccatta taacggatta
  1034041 aaaatgggaa cgaaataggg gagatctttc aatgatcagc aaattcacgg ccgtcgcggg
  1034101 cttcgtcgcg gctgtactgg cgggcatgcc tgcgcacgca caacaggctt cgagcaagct
  1034161 tgacgaggtg ctgagtcgcg gccatctgat actcggcacc ggcagcacca acgcgccgtg
  1034221 gcacttcaag agcgccgaag acaagctcca aggtttcgac gtcgatatgg gccgcatcat
  1034281 cgcgaaggca ctgttcggcg atccggagaa aatcgagttc gtcaaccaat cgtcggatgc
  1034341 ccgaattccg aacatcacca ccggcaaggt ggacatcacc tgccaattca tgaccgtcac
  1034401 cggggaacgt gctcagcagg tcgccttcac tattccctat tatcgcgagg gtgtcggcct
  1034461 gatgctgaag gcggacggca agtacggcga ttatgaagcg ctgaaggccg cgggttcgtc
  1034521 ggtcacaatc tcggtcctgc agaacgtgta tgcggaggac atggtccacg cagccttgcc
  1034581 ggaagcagcc gtggatcagt atgagtccgt cgacctgatc tatcaggcgc ttgaatccgg
  1034641 ccgcgctgat gccgccgcca ccgaccagtc ctcgctcgcc tggtacatga cgcagaattc
  1034701 cggacgctat aaggatgccg gctacggctg gaacccgcag acctatgcct gcggtgtcag
  1034761 gcgcggtgat caggattggc tgaacttcgt caacacggcg cttcacgaag ccatgaccgg
  1034821 cgtcgagttc gatttctatg ccaaatcctt caaaacgtgg ttcggcaagg acctaacgcc
  1034881 gcctgagatc ggctttcccg tcgagtacaa gtgatcctga catggcggct ccgccggctg
  1034941 gcggagctgc cttgtccgat agaatggctg ccccatgact tactccttga acttcgcggc
  1035001 tgtctggcgc tcgttcgacc ttcttctgca gggattgtcc ctcagtctcg gcctggcggt
  1035061 cgtggcgatc gtcgtcggtt gcatgatcgg gctgatcacg gctttcgggc tcgtttccaa
  1035121 gagcgtggct ctgcgaaagc cagccggctt ctatgtcacg gcgatccgca acacgccgat
  1035181 tctcgtgctc gtcctcttca gctatttcgc gcttccagaa ctcggagttc ggctcggcaa
  1035241 aatcgaaagc ttcgtgctga cgcttgcaat ctattcgggc gcatatcttg ccgaggtgtt
  1035301 tcgcggcggg ctcatcgcca taccgccggg ccagcgggaa gcggggctcg cgatagggct
  1035361 cacggaaatg cagatccgca cctcgatcac cattccgctg atgctccgca gcgtcctgcc
  1035421 gtcgctcggc agcacgataa tctcgctttt caaagacact tcgcttgccg ctgcgattgc
  1035481 tgttcccgag ctcactttcg aggcgcgcaa gatcaatgtc gagagcttcc gcgttatcga
  1035541 gacctggatt gtcgcgagct gcctctatgt cgcaacctgc tcgctgctcg ccgcgcttat
  1035601 gcgcggtgtg gagcggcgtc tcgctgtgcc gaggtgaccg ccatggaggt ctctttcatc
  1035661 gatcagcttt ggctcgcccg cattccgctt ttcaaagggc tcgggatttc cgtttcgatc
  1035721 tcatttcttt ctatcgtcgc cggcacggtg ttgggcgttt tcgtcggtct ggcgcttgtc
  1035781 tatggataca ggcccgtcag atggatcgtg cgcggttata ccgatttcat ccgcggcact
  1035841 ccggtgctcg tcctggtgct cgcgagctat tacgtcctga gcgccattgg catcgatctc
  1035901 gggccgttcc aggccggcgt tctggcgctg gccgtcttct gcagttcgca tgtcggcgaa
  1035961 ctggtgcgtg gcgccctgca atcgatcccc aaaggtcaga ccgaggccgc caaggcgatc
  1036021 ggtctgacct tcgcccaaac cttcgcctat gtgctcggcc cgcaggcgtt gcggcaggcg
  1036081 cttccggcct gggtcaatac ggcggccgag atggtcaagg catcgaccct gctttccatc
  1036141 attggggtcg gcgaattgct cctgcgcacg caggaggtga tctcccgcac tttcatgagc
  1036201 ctcgaattct atttcttcgc gggctttctc tacttcgtca tcaactacgg cattgagcgc
  1036261 ttcggccgtt acgtcgagcg caagaccgcc gttccatcgt gaggcttcgc atccgatgac
  1036321 caatcttctt gaaatacgtg atcttcacaa acgttacggc gcggtagagg tgctgaaggg
  1036381 cgtcgactgc tcgatgcgcc aaggcgaggt gatcagcatc atcggctcca gtggctcggg
  1036441 gaagacgacg atgcttcgct gtatcaacat gttggaggag tttcagggcg gcacgatcgc
  1036501 gatcgatggc caggaaatcg gttacgaaac cgcaggagac gctcgccggc gcaagccgga
  1036561 gcgggagatc gcccgccagc gcgccctgac cggcatggct ttccagcagt tcaatctgtt
  1036621 tccgcatatg acagccgccg ccaatgtcat gctcgggctc gtcaaagtga agaagatgag
  1036681 ccgcgacgag gcgaggggac ttgccgaaaa atggctcgac cgcgtcggtc tgctctcgcg
  1036741 aaaggatcat tatcccggac aactttcagg tggacagcag caacgcgtgg cgatcgcccg
  1036801 tgccattgcg atgaatccga agctgatgct cttcgacgag gtgacctcgg cgctcgatcc
  1036861 cgagctcgtc aacgaggtgc tgcaggttat caaggggctc gccgatgatg gcatgagcat
  1036921 gctgatcgtc acccatgaga tgcgcttcgc ctacgaggtt tcgtcccggg tgatcttcat
  1036981 gaatcagggg cgcatcgccg aggaggggga tccgcgcgaa atgttcctga agccgaggac
  1037041 cgaacgcctc gcggagtttc tgaagacgtc gacattcaac tgaccgagta tgaatctgat
  1037101 aagaagtgga gtgaagcgtg acaatcaagc gttatggaac tggggaaacc ggtgcgggca
  1037161 agcagcccct gccatttgcg cgcgccgtgg aggcgaacgg gtggctctat gtgtctggtc
  1037221 aggtcgccat gcaaaagggc gagatcgcgg gtggcggcat catcgcggaa agccgcaagg
  1037281 ccatcgagaa catgatcgca atcctgcacg aagccggcta tgggctcgaa gatgtggtgc
  1037341 gggtcggcgt ctggctcgac gatccgcgcg acttctggac cttcaacggc atctatgcgg
  1037401 aatatttcgg cgagcatccg ccggcgcgag cctgcgtcca gtcgcgcatg atggtcgact
  1037461 gcaaggtgga agttgactgc gtggcctaca aggctaaatg aggtccagag cggatttgag
  1037521 cggcaaggag gacgcggtgg catatgcgga tgacacgatt aatcgcaggg cacgtggcct
  1037581 cgatcgagcc ttcgagatcc tcgacttcct acgcgtgcag cgtcagccct tgcgcccgaa
  1037641 cgagatcgct caagggatag gagcgccgcg ctcgtctgtc tatgaactgg tcaacctgct
  1037701 cctgcgccag aacattctcg aatatcgcgg cgatgacggc cgggtgtttc tcgggcgcaa
  1037761 gctctatttc ctcggcgcgg cctatgcgga gcagttcgat ctgatgcgtg aatgcgagca
  1037821 tctcctggca aggattgccg gagagacgcg cgagacggcg cagatgtgcc agctcgaagg
  1037881 cagtaaatat gccgtcgtgc tgatgaacga gggcagccgc cctttccgca tttccaccag
  1037941 tataggcgag cccgtcgcta tcccgtggac tgcctccggc cgcctcctcg tcgatcacat
  1038001 gagcgacgag gagattatcg cattcattcc gccggaggat ttcgttctgc cggatggcac
  1038061 gcggcttgag cccgccgaat tcatcgctca ggtccgcaat gccaagaagg agggctattt
  1038121 caccttcaac agcatcgtcg acagcttcac ccattgcttc gccgtaccgg tctatgacgc
  1038181 ggaagcgatt tgtattgcga cgctctgcct cgttgcgccg aaggaggacg gtctgcgcaa
  1038241 tcgggacgcc tatcttcgcg tgctgatcga cggggcgggc gaactctcgg agaagcttgg
  1038301 ctaccgaaac gaccttgcgg cttcggttag ggcggcaagc gctcgttgac tgagcctcgc
  1038361 ctcatcccac tttaagcgat cggccgcttt ccggatcgaa aagatgcatg gccgtttcat
  1038421 cgaaggtgaa ggcatgtacc gaacccgtgc cgagtgctgt gcgcggcggc aggcaggcgg
  1038481 tgatgcgctg cctgccgact gtggccgtgg tcacgagttc cggtcctgtg agttccacca
  1038541 cctcgatgtc agcggtcaat cgcggatcct ctgactcggc tgcgagccgc attgcctccg
  1038601 gccggatgcc gaccttcgcg cgccgacccg ccaaggcggt cccgtcgaat gctgccggca
  1038661 agggaagcac ctcctcgcag ccgtcgagct tcaggccgct tgcggtcact tcggcatcga
  1038721 gaatgttcat cggcggcgag ccgacgaagc cggcgacata gagcgttgcg gggcggtcgt
  1038781 aaatctcttc cggcgtggcg agctgctcga tgcggccgtc gcgcatcacg gcgatgcggg
  1038841 ttgcgagcgt catcgcctcg atctggtcgt gggtcacgta gacgactgtc gttttcagca
  1038901 tctggtgcag gcgtttgagt tcggtccgca tctccatccg gagcttggca tcgaggttcg
  1038961 acagcggctc gtcgaaaagg aacacctggg ggtcgcgcac cagagcccgg ccgatcgcga
  1039021 cgcgctggcg ctgaccgccg gagagctggc tcggctttcg ctcgagaaga tcctcgatct
  1039081 gcaagagcct ggcagtgtcg caaacagccc tgtcgcgctc ggcccgcggc acccggcgca
  1039141 tttccaggcc gaagccgatg ttgcgggcga cggtcaggtt cggatagagc gcataggact
  1039201 ggaagaccat tgctatgtcg cggtctttcg ggtgaacgcc cagcaccgag cgttcgccga
  1039261 tcaggatgtc gcctccgctc ggttcggaaa gtccggcgat gatattgagg agcgtggact
  1039321 tgccgcatcc ggaggagccg agcagcacga ggaattctcc gctttcgagc gcgatatcga
  1039381 tgcccttcag cgtttcgacc tcgccgtagc gcttacggac gttgcggatt tcgagggcgc
  1039441 tcatcgcctg gattcctcga taaaggcgga aaggggcttg ccgtagcggc gcggaagagt
  1039501 ggagatcgct tgcgaagcga tcgtaacgcc ggttttgaga cagtctatga gcggcatgtc
  1039561 ggcggcgaga gctgccagga agccggcatt gaagacatcg ccggcaccga tcgtgtcgac
  1039621 gacctgaacg ctgggtgccg gaaacgagaa cgctgcaccg tttcgatcga tggcgagcgc
  1039681 tccgttgggg ccgcgcttaa cgacgacgat cgcatcggcc ggcatttcgc ttttcaggct
  1039741 gcgggcggct tcggccggat cggactgacc ggtcagcgtc gtcgtctcca cctcgttgaa
  1039801 aagggcgcag tgacagcgct tcagccaggc gagcgtcttg agcctgttgg cctcggtcca
  1039861 gccctcgagc ggccagccgg tatcgagcgc tacggctatt tcgtgagcgt ccgcccagtc
  1039921 gaaaagcgca tcataggcga gcgagagggc gtcggtcagg aaggagccgg agagcagtgc
  1039981 atagccgccg cggaggcgat ttccatccag cattgtccgc acttcctgga agctgagcaa
  1040041 tggcaggtgg ccgcgggtcg tgaagaaggt ccgttctcca tccggatggg tgatgcccac
  1040101 cgaaagcgtc gtgcccgcgg cttccaccgg ccaatcgcgg gacctgtcgc cgaaggcctc
  1040161 cttcaaccag gccccgaact ggtcgttgcc gacattggcg gcgatcacat agtccacgcc
  1040221 aagggactcc caggccagcg cattgttgcc ggcgcaaccg ccgacgcgaa gctcgtcgtg
  1040281 atcgacgatg atctcggtgc caggtttagg ccacggttcg gcgggaccaa gtatgagatc
  1040341 gacattgacg ttgccgatgg ctgcaagcgg acgcatcttc actcgctccg ggtgaccttg
  1040401 gtggatcgta ccggcgtgcc ggcattttcg acgcgagcgt cggcgaaggc gatcatcagg
  1040461 gactgtgcga cgggcagcat cgcgaagatc gcagccatgc ccgccgccgg ttcgaagcgg
  1040521 atcgtcgtgg cgccggcggc cggcggctcg cccgatgcat cgaagacgac gaccggcgac
  1040581 ccggcttcgg ctgccgaaac cgccatggcg ccgacgaggc cagcggtcgg atcggctgcg
  1040641 cggaagagaa tgacggccat tgaaggaccc agcatttcca taggtccgtg gcgcaattga
  1040701 ccgccttcca gcgaaaagca cgggaggcga gagagctcgg tgaggccgag ggcgatggct
  1040761 tcggcgatgc cctgcagtct gcgtccggag gtgacgattg cgctgacacc ggtaagcatc
  1040821 gccagagcgc cgtcgatcgc cggtgcttct ggagtcttga gggcgcgaag ggcctcggcc
  1040881 ggatccgcgc cgagggcggc gagtatcgcc aggtgcagcg cgaaagtaac cgtcaggctg
  1040941 cgggtggccg caaatgcctg ctccgtcccg cctgccccga cgagcgaagg gatagccttg
  1041001 gccaggaatg catcctcttc gagtgtcagc ccgaatgtct cgctcgtgcc gccgtccgtt
  1041061 tccctaaacc agcgcagcac ttcggcactt tcgcccgatt gcgatgtcac gagaatggtc
  1041121 ttgccttcga ttggaagcgg ttggccgagc tgctcggaaa gcggcagcgc gacggcatcg
  1041181 atgccgagag cgcgatagag cggctcgact gcgcgggcga cggcgtgcga gccgcccatg
  1041241 ccgaggagca gcagccggcc cgtcgacttc agcgacgcgg cgatgcgttg agccgtggct
  1041301 gccgcttcct gataggaagc gacagcgtcg ccgtgctgac gcgccatctc acgatcgatt
  1041361 gcaacaagcc cggcggggcg gtccttcgat atgctcatgt tcatcccttg acgcccccac
  1041421 tggtgagccc ggagatcagg gctctttgca tgacaaggcc gaccagcacc gggggcaggg
  1041481 cggcaagtac cccggcggtg gcgatcagcc catagtccga aacccggccg ccggcgaggt
  1041541 ccgcaatggc aaccgtcagg gttttggcgc gctggtccga ggtgaagagc agcgcataga
  1041601 agaactcgtc ccaggcgagc aggaaggcga agagcgccga ggtcgccatg accggtgcag
  1041661 ccagcggcag cgtcagaagc cgcaggatat ggtccagtcg cgcgccgtcg atcatggcag
  1041721 cgctttcgat ctcccgcggt atcgtgtcga agcccgattt caggagccat gtcgtaaagg
  1041781 gagcgagaat ggtgagatag acgagcgcca atccaaagac tgaattgagc aggccgaaat
  1041841 gggcaaggcc catgtagagc ggcacggcaa gagcgacggg cggcagcatg taggtcgcga
  1041901 tcaccacgta aaacgaccag gagacggagg gggtgcgaga cacggcccag gcggccggaa
  1041961 cggcgacgac gacagcggcg agcgttgcca tgcctgccac cttcaggctg ttcaggagcg
  1042021 atgcaatgaa ggctgcgccg gcgctatttt cgacagccga caaaagtgtg cgatagcgcg
  1042081 agaggtcgat ttcgctcggc caccaggcga ggggcttggc gctgagatcc gcggcgggcg
  1042141 agatactcat gatgaaaagc caggcgaccg gtgccaggac cacgatagcg agaaccaggg
  1042201 cgctcgcatg gatgaagacg gagaaaagcg ggctttgacg ttccatcacg aagctccggc
  1042261 ggccttgcgc agcagcgcgg cataggcgac ggcaagaatg gtcaccagca gcgtgacaat
  1042321 gagggcaagc gacgcgccgg agcccgctcg ctggaaggaa aacgcttcct ggtagacgag
  1042381 gatcgagagc gtgcgcgtgc tgttggccgg tccgccgcgc gtcatgaccc agatgatgtc
  1042441 gaacaccttg aaggcctcga tggtgcgcag caccagcgcc accagcaagg gaccggcgag
  1042501 gtagggcagg atcacgaagc gaaatcgatt gaacggaccg gcaccatcga cgatcgatgc
  1042561 cgcattgatg tcgcgcggca cagcctgaag cgcggcgagt gcgatcagcg ccaccagcgg
  1042621 gaagttcttc cagcaatccg cgacgatcag cgctgcaagc gccgttccgg gttcgccgag
  1042681 ccaggagcga tagctgtcga ggatgccgat ctgggtcagc cccgcattga gcgcgccata
  1042741 ttccggattg tagatgaggc gccagagcgt cgcattgact accgtcggaa gcgcccacgg
  1042801 caggatcatc agtgcgcgga gcgccgtccg tccacgaaat ttctggttaa ggaggagtgc
  1042861 cgcaaggaca ccgagcacca tttctgccgc aaccgaaatg actgcgaacc aggtggtggt
  1042921 aatcagcgcc cgctgaaagt tcgagccagt gagcattctt gcataattgt ccactccgac
  1042981 gaagccgcct tcggttccga tgagcttggc gtcggtgaag gaaagccgca cggtgtcgat
  1043041 gagcggccag ccgatgacgg cggtcatcac cacgaggagc ggaagcatca gaagccacgc
  1043101 gcgcgttgag atccaggtgc ctgtcatcgc tcaaggaccc tcattcccgt aacaagaagc
  1043161 acaggcatca ggcgggaaat gcgtccgcaa cgccgcgtgt accttgcgcg ccgtacattc
  1043221 cccgcccgac cacgaccgtt cacacgcaca tcggctcaca agccactgtt ctcagcggcg
  1043281 ctcttcagcg cgtcttccgc agaggcttgg ccgagcagcg cctcctggat ggcctgctgc
  1043341 agggcagccg aaagctcctg gtatttcggc gtcgttgggc gtggatacat ggcggccagc
  1043401 ccgcgcttcg ccgcagcgat gagttcctcc tggcccttgg tcacatcggg gtcttcatag
  1043461 gaagatgccc agatcgggag gctcagcttg gcataggcgt tctgcgtctc ctgcgaggtc
  1043521 atgtggacga tatatttcca tgcttcttcg gggtgcttgc tggtcgtcgt gatgccgagg
  1043581 cccatggagc cgttgacggc cgaaacctcg cttttgcctt caacgccggg agccggaacg
  1043641 acgccgacct tgccggctac cttgctctcc ttgggatcgt tggcgaggtt gtacatgtac
  1043701 gtccagttga gcgcgaaggc ggcctcgccg ttctggaaga ccttgcggac atcctcctcg
  1043761 aggaactcct tggaattcgg gttggtgagc ccggaggtgt agctcgtcac catgtagttc
  1043821 agcgcatcga gcccgccgcc gctggcgaag gccggcttgc cgctatcgag gaattttccg
  1043881 ccataggcac tgaccagagt ggtgtagtcg cagatggccg cttccgcttg agaccagctc
  1043941 caggcgatcg ggttttcgag cagtcccttg tccttgatgg ctttggcttg ttccgcaagc
  1044001 tcgtcccagg ttttcggcgg ttccttgatg ccggctttct caaggatttc cttgttgtag
  1044061 aacaggtact tcgtgtcgag gatccacggc atgccgtaac gtttgccgtc atattccacc
  1044121 gtcgtccagg cgccgggcag gacgccttga ttgatctcgt ccgtgatgcg gtccgtcacg
  1044181 tcgaggagaa cattgttggc tgcatattcc gccggccaga tgacgtcgaa aaggacgacg
  1044241 tcatagccgc cgccggaacc ctgcgcgagc accgtcttgt cgtgcagtcc ctcataggga
  1044301 acgaattcga gattgacctt gatgtcggga ttggccttgg cgaaggcatc cgtcatggcg
  1044361 cggacgtctg cctcgctata ggcggcctgc gccatgaaaa gcgcgttcag agtcgtttcg
  1044421 gcctgggcat ggccggtgaa gccggcgccg acaagggtcg cgccgatcaa agcgttgcgg
  1044481 atggatttcg acatcgtcgc ctccagtaaa tgaccgttgc agtcttcgca gcgcgcgtgg
  1044541 gcgcgctcca gtggaattcg gctcgcttcg cggccgggct tcgacaaatc aaaccggagc
  1044601 gttcgcggcc cattgctggc cgccgtcgtt cccccgaggt tctccgacct cttattaagt
  1044661 caattgtctt gacttaactc ttgttcgata gtccagtcgt gtcaagaggg tttgtgaatg
  1044721 aacgaaattc gaccggtccg ggccaaaagc ggcaccaatc aggaaggcgc gagcgcccac
  1044781 aatcgccgcg tgatgatcga tgctttgcga ctgaacgggc acctgtcacg ggctgatctt
  1044841 gcgcgggcga cagcactcac caagcaggcg gtctccaaca tcatagagga gctcgagaac
  1044901 gacgggctcg tggcatcgct cgccgcagtg cgcaaaggcc gcgggcaacc atcgacaccc
  1044961 tatcggctcg tgccggaagg cgcttttgcg atcggacttc agatcgaccg tcacgtaaca
  1045021 cgcacgatcg ccgtcgacct gatcggcgcc gtgctgatcc gtaaagaggt gaacctgccc
  1045081 ggcggcggcc ctgaagaggg tgtcgatgca atcctcgctc tgatagacga aacacggcgg
  1045141 gaactggtga cgaccgctcc ggaattcaac gaccgcctgg tggggctggg cgttgcaatg
  1045201 ccgggaccgt tcggcatcga ctccgctacc gacgacccct ggatgatggc ggcgtggcaa
  1045261 agctttcccc tgcttgaacg actttccgag gggacggggc tcgacgtgcg ccttcagaac
  1045321 gacgcggctg cggcggcgac ggcggaaaag atggtcggtg ccgcccatgg gatcgaccat
  1045381 gccgtctgcg tttatctggg ctacgggctc ggtgcgggac tgatcctgaa cggtgaactc
  1045441 taccgtggcg ggcacggtaa tgcgggcgag atcggcatga tcctgagcag ggcgcgcgtc
  1045501 ggtgccgacg acgcgagggc accgatcgag caccgcatat cgatcgcttc gctgtgcaag
  1045561 ggcctcgaca ttgaccccgc cgatcccgat ctttaccggc gcatcgatgc tgccgccggc
  1045621 tcaaaggaca ggcgcgtgat ggactggatt gcgggcgctg cccacgagct tcgggcgacg
  1045681 atacagttgc tcgagacgat tttcgatccg caaacgatca ttctctgcgg cggcatgccc
  1045741 cccgttctcg ccaacctcct gatcgacgcc cttcaccccc tgctgccttc gattgccgag
  1045801 cggcggcagc gcagcacgcc acgactgcag ctgggcttca cggacccatg ggcggttgct
  1045861 gtcggtgctg cggccgagcc gatcagccgg acgttcgacc cccggttttc ggcgatcctg
  1045921 aagagccggg tcggtggaac gctttgatcg aatactcggc ttccggatac gccttaaaaa
  1045981 aagacttccg attattactt gaaatataag cgagatggcg cttaaatgcg cgctcgtcgg
  1046041 tgggacatca tttaactgct gtacgattat ttgatcacgt tcgcagcttt tagcgcgcgg
  1046101 cggcattttt attcgcatgc aatattttta ttatttaaaa tcagagggat tgcgatatgt
  1046161 ctcttcccca tcttcggcgg cttgaagccg aagcgatcca tgttattcgc gaagtcgttg
  1046221 caacattctc caaccccgtc gccctctact caatcggtaa ggactcctcc gtattgctgc
  1046281 atctggcaat gaaggcgttc tatcccggaa aaccgccctt tccattcctg cacgtcgata
  1046341 cgaaatggaa gttccgggaa atgatcgagt tccgtgatcg gatggcgcga gagctcggct
  1046401 tcgacctgct cgtccatgtc aatcaggacg ggatcgatca gggcatcggc cccttcacgc
  1046461 acggctccaa cgttcacacc cacgtcatga agacgatggg actgcggcag gcgctggaga
  1046521 aatacggttt cgacgcggcg ctggcgggcg cgcggcggga cgaggagaag tcacgcgcca
  1046581 aggagcgcat cttttccatt cgcagtgccc agcacggctg ggatccgaag cgtcagcgcc
  1046641 ccgagatgtg gaaaacctat aatacgcggg tcgcgccggg tgaaacgatg cgtgtcttcc
  1046701 cgctctccaa ctggaccgaa ttcgacatct ggcaatacat cctgcgcgag gacattccga
  1046761 tcgtgccgct ttatttcgcg gcctggcggc ccgtcgtaaa gcgcgacgga acgctgatca
  1046821 tggtcgacga tgagcggatg ccgatccagc ccggagagga ggttcttgag catcaggtgc
  1046881 gtttccgtac cctcggctgc tatccgctga ccggggcggt cgagtccgag gctgccacgg
  1046941 ttcccgacat attgcgggaa atgctgacgg tccgcacgtc cgaacgacag agccgcctca
  1047001 tcgactcgga tgaagtcggg gcaatggaga aaaagaagcg ggagggctac ttctgatgtc
  1047061 atatgttcaa tccataccgc cgcatgacat tgaagcgcat ctggttgagc acgacaacaa
  1047121 gtcgatcctg cgattcatca catgcggttc ggtcgacgat ggcaaatcca ctttgatcgg
  1047181 ccggctgctc tacgatgcga aactgatctt cgaggaccag ctcgcaaacc tcggacgtgt
  1047241 cggctctccc ggtgctgcca atggcaagga aatcgatctc gctttgcttc tcgacgggct
  1047301 cgaggccgag cgcgaacagg ggatcaccat cgacgtcgcc taccgctatt tcgcgacgtc
  1047361 gaagcgcaag tttatcgttg ccgacacgcc cggtcacgaa gaatatacgc gcaacatggt
  1047421 gaccggcgct tcgacggcgg atcttgccat catccttatc gacagccggc agggcattct
  1047481 tcagcagacg cggcggcatt cctatatcgc ctcgcttctg ggcattcgcc atgtcgtgct
  1047541 ggcagtcaac aagatcgatc tcgtagactt tcgacagcag gtctatgacg aaatcgtcgc
  1047601 cgactacatg gcttttgcga aagagctcgg ttttgccagc attcggccga taccgatctc
  1047661 agcacgagac ggcgacaacg tcatttcggc ttcacccaat acaccttggt acagaggggc
  1047721 ggcgctgctc gaatatctgg aaacggtaga gctcgagccc atggaccagg ccaagccttt
  1047781 ccgtttcccg gttcagatgg tgatgcggcc aaatgctgat ttccgcggct atgcgggtca
  1047841 gatctcctgc ggcagaattt ccgtcggcga tccggtcgtc gtcgcaaaaa ccggacagcg
  1047901 gacctcggtc aaggcgatcg tgacctatga cggggacctt gcgacggcag gcgagggcga
  1047961 ggccgtaacg ctcgtccttt ccgacgaggt ggatgcttcg cgcggcaata tgctcgtcgc
  1048021 ccccggcgcc cggccgttcg tggcggatca gttccaggcg catgtgatct ggttcgatgc
  1048081 gagcccgatg atgcccggac gaagctatat attgagaacg gagacggaca gcgtcagtgc
  1048141 gacggtcacc gcgctcaagc atcaggtcaa catcaacagc ttcgtgcgcg aggccgcgaa
  1048201 atcgctgcag atgaatgaag tcggcgtctg caacatctcg acgcaaacgc cgatcgcttt
  1048261 cgacgcctat acggacaatc gagccacagg caatttcatc atcgtcgacc gggtcacgaa
  1048321 tgcgaccgtc ggcgcggggc tgatcgactt tccactccgg cgtgccgata acgtccactg
  1048381 gcatgcgctc gaggtgaaca aggtcgcgcg cagcgccatg aagaaccagc ttcctgccgt
  1048441 tctctggttc accgggcttt cgggctccgg taaatcgacc attgcgaacg agctggacag
  1048501 gattctccac gctcagggca agcataccta tctgctcgac ggcgacaatg tgcgtcacgg
  1048561 cctcaaccgg gacctcggct tcaccgaaga ggaccgggtg gagaacatcc gtcgcgtggc
  1048621 ggaggtggcg aagctcatgg cggatgccgg tctcatcgtc ctcgtctcct tcatctcacc
  1048681 gttccgggac gagcggcgaa tggcgcggga attgatggat gatggcgagt tcatcgagat
  1048741 cttcgtggac actccgatcg aagagtgcgc gcgccgggac ccgaaggggc tctatgagaa
  1048801 agctctcgca ggcaagatcg caaacttcac cggcgtatcc tcgccttatg agaccccgga
  1048861 aaacccggag cttcatatcc gcaccgtcgg ccatgaaccg accgacctgg cgctcgcgat
  1048921 tgaggaattc ctcgaccgca ggatggaggg caaatgacgc cgctttgcca aatattcgag
  1048981 cacatagcgc ttgaagcggg tgcggccatt ctcgaggtct acgacgccgg tcccgaggtc
  1049041 tgctacaagg atgatcaatc gcccgtcacc gaagccgacg agcgagccga agcgatcatc
  1049101 cttgagcggc ttgccgcggc gtttccgggg atccccgtcg tcgccgagga gtctgtctgc
  1049161 tcgggccgcg tccctgatat aagcggtggc tcgttctttc tcgtcgatcc gctcgacggt
  1049221 acgaaggagt tcatcaaccg ccgcagcgac tttaccgtca acattgccct catcaagggc
  1049281 aatgttccgg ttgccgggat cgtctacgca ccggcgcagc gttgcgctta tgtcgccgat
  1049341 gggggcaggg cggagaagct tctgctcgac aagctctggg cgctcgaaca ccgtcagccg
  1049401 atccgcgtgc ggatgcgggg tgcggaactg acggcggttg ccagccgctc gcacaacagt
  1049461 tccgaaaccg aggcttttct caccgggcac ggcgtcatga actatgcgtc cgtcggctcg
  1049521 tcgctcaaat tttgcctgct ggcggagggc aaggcggacg tctatccgcg tttcggccgc
  1049581 acgatggagt gggatacggc ggccggggac gcggtgctga gggccgcggg cggatcggtg
  1049641 gtacgtttgg acggctcgcg cctgctctac ggcaagacga tgcaggacga ggacagcgac
  1049701 ttcgcaaatc cgcacttcat cgcctgggcg gatatgtccc cggtccattt aacggctgcc
  1049761 gagggcgttg gggcggctca tgcgctgacg tgaacagcac gttgtccgcc gggagctctt
  1049821 gtaagaggca gattagaagc atgaacgggc aggaatcgat atgcactagc aggcccgtgt
  1049881 tccaccggta ccgggatctc agccgagcgc gattgaatgt ggagctgcag gtccacacga
  1049941 gttggaccga cgggcaggcg actgcgctcg aaatcctgca aacggccaag gaacgcggtc
  1050001 tcgcggcgtt ggcgttcact gagcacgtgc gcgaagacac gacatggttt ccccggttca
  1050061 gggaggaagt cctttctgcc gcgcgtggtt ttgacgatat cagcgtctat gtcggttgcg
  1050121 agacgaaagc catggacgag gacggccggc tggatgtgtc gcaagatgtc ctggatcggt
  1050181 gcgacatcgt tctcggcgtc gttcacaggt tcccggatgg ccgcggcgga tatctggact
  1050241 tcgagcagct ttcttatgaa aaaacggcgg atctcgaatt ccgcctgtcg atgggcatgg
  1050301 tcaaaaacgc gcccatcgac gtcctggcgc atccgggcgg aatgagcctg agacggcacg
  1050361 gtcgttttcc ggaagcctgt ttccgcgaca tgatgaccgc gaccctcgaa cggcagatcg
  1050421 cgatcgagat caactcctcc tacctcgtcg acatgccggc gttcctcgcg ctgtgcgaag
  1050481 aagtaaaccc gttcgtttcg atcggttccg atgcgcatcg gctgagcgaa ttgggtcatt
  1050541 gcagagatca gctactcgaa ctgggagcag ggcagtcatg aaggtcttta taaccggggc
  1050601 gggtgccttg ctcgggcaag gcatcattcg cgccctgcgg cgctcgactt tgaatgcgag
  1050661 gatcattgtg ggggacccga gcccgctctc ggcagggctg tactgggggg atgccgccta
  1050721 tctcgtgccg atggccaagg acccttcata tctggaccgg cttggggaac tcctgcgtgc
  1050781 cgaacggccc gaagtcctca ttccggggac cgacgtcgaa cttccgatcc tcgccgcgaa
  1050841 cagggatgcg atcgagagaa cctacggaac caaggtgatc atcagctcgc cgcgggtggt
  1050901 gtcgatcgcg aacgacaagt ggctcacctc cgagttcttt cgcgagcgcg gcctgggata
  1050961 tgttccctcc tgtctgccgg gcgacgaaga cgctctgatt gaggagtgcg gatttccgct
  1051021 catcgtcaag ccgagagtgg gggcgcgttc gatcggtttc agcgtcgttc gcaaccgcga
  1051081 gcaactgatg cgtgcaatcg aggagcagcc cggcatcgtc attcagaaat atgtcggtgc
  1051141 cgaaaccacc gagtacactg ccggcacgct gacattcgac gggaaatgcc gcgcgacgat
  1051201 cgtcatgcgc agggaccttc gcgacggtaa tacctacagg gcattcgccg agcctttccc
  1051261 ggcgctgaac aaggctatgg cagaagctgc cgatgccctc ggcgcctatg gcccggcgaa
  1051321 cttccagttt cgtctggacg acggtgttcc ccgcatcttc gagatcaatg ctcggttctc
  1051381 cgggacgacg gcggtcagga tccatgcggg cttcaacgag gtggagatgt gcatccgcca
  1051441 tctcctgttc gaggagcccg tcgagcagcc gcagatcacc ccggtgacga tattgcggca
  1051501 ctggtccgaa accgtggtga agcccggtga actggtgacg gcttcttcga aactcgacga
  1051561 aacggtgtga agacaatgcg gctggtagtg accggcgcga ccggcttcgt cggtgccagg
  1051621 gtgatagatc gcgctctgtc gcgtggttac gaggtcaccg cgcttgcacg tgatccggag
  1051681 cggatcgcaa ctcggaaggg ctcggggctc cgtgtcgagc aatggacggt tggcgatcct
  1051741 ttgccgccgc tcggtcgatc cgacgccgtt cttcatcttg ccgcccacat tcccgccgat
  1051801 ctcagcgatc cgcgtgaggc ctcccggtgt ttcgaggtca acaccaacgg tgcactggaa
  1051861 gttgccatgc aagcggcgct gcaaggggtg agccgattcg tgcagttcgg gtcggcgcag
  1051921 gtctatgctc ccggcacggg cccagcttct gaaacgagcc ccgcctttcc cgtgcaccgg
  1051981 gcgagctact atctggcgag caagctcgcg gcggagattt gtctgctcgc cttcggcaaa
  1052041 gccagcgcca tgccggtaac ggtgctccgc cttgcttcgg tttacggtcc gggaatgcac
  1052101 gacgccggga tggtgcccac cttcgtgcga acgcttggaa ggagaggttc cctgatcatt
  1052161 caggacggcg ggcgatacac cgtcgatctc gtctatgtcg acgatgtcgt gtcgctggcg
  1052221 ctcgaggctg cggagagagc cgaaggcggc gtcttcaacg cgggaagcgg acgggcctgc
  1052281 acgtcgctgg aagccgcccg tatcgtcgcc gatgccgttg gcgccgaaca gcacctcata
  1052341 gccgtccagg gcggcagtat cgatgcgccg ccgcccggct tcagggccct cgatgtttcc
  1052401 aaggccatag acgggctgaa ctatgcgccg ctttccttcc gagaaggaat tgaagcatgg
  1052461 agaacgatga cgggcctgac cgattttcag gatggagcgt gaacgggtag aacgcgaagc
  1052521 gccttgccgc gcgcccatcg gacgtgcgac gtcgacgcgc tcgttcatcg atcaggcgaa
  1052581 aaggaaatcg ctgctcgaaa agtttgcggc actaagggtg ccgttgggat cgtccaccag
  1052641 aatggagaat gccgtgccgg cggcgtcata gccttttacc agcacgtcgc cgccggtggc
  1052701 atcataggcg tagacggtgc ccgcggcgcc tgaactggag tattgcttga tcccgagctt
  1052761 ctcgatgacg agaaaatcga ctccatcctg gaagtccatc acggtatcct ggccgctgag
  1052821 cgctacggcc cctttgaaga caaaacggtc ggattccgtt ccgccccaga gaatgtcgct
  1052881 tcctgcctcg ccgacgagga cgtcctgtcc ggcgtcgccg cgcaaggtgt cgttcccgtc
  1052941 gccgccgaaa atgcggtcgt agttgttgcc gccgctcaaa gtatcgttgc cggcttctcc
  1053001 gtacagcatg tcatcgccgt cttctccgaa gacccgatcg tcgccggctc caacaacaac
  1053061 cttgtcattg ccgctaccgc cgtgcgcctc gtcgatgccc ccctcggaat ccagcacgtc
  1053121 gttgccttcg ccgccgtcga gatagttgtt cccgtcgccg ccgtcgacga tgtcgttgcc
  1053181 gatgccgcca taaacccagt cgtttccgga ctggcccttg agagcgtcgt tgccatcttc
  1053241 gccatagatc ttgtcgtggc cggcgccccc gctgaccgcc tgctgcgtga cctgtcccgt
  1053301 ggcggggttt acccggttgt tgaagccatc gtctccggag ccggcataaa tgatatcgtc
  1053361 gccgtcgcct gcgtcgatgt attcttcgcc cgcgccgccg aagatcttgt catgtcccct
  1053421 gccgcccagg atctgatcat ggccatcgcc gccatcgaga acgtcgctgc cgtcgccccc
  1053481 gtcgaagatg tcgtttccta atccaccctt caacgtatcg tgcccaaggc cgccgttgaa
  1053541 gcggtcgttg cccgccccac cttctgcata gtcgtcgccg aggccgccga cgatgaagtc
  1053601 gttaccatcg ccgccaaaaa tcttgtcgtt gccatcgccg ccgtcgagat gatcgtcgcc
  1053661 ggcatagccc cagagctcat cgttgcccag agcgccgttg atcgtatccg acagattggt
  1053721 tccctttaga atcatttcga tctcctctag ctatgggccg gagggcgggt aaattgagaa
  1053781 tagggcgcaa agtgatcctc agcctatagt cgcctgccgc caccagaaat acattcattt
  1053841 caagaaaaat tgagaatact gcttatgtta gaagccataa attacacgca actgcattta
  1053901 aatcagacgc actgacccaa gattgcatta gtctaccgga aaacaccata tgcgcaacgc
  1053961 acccgaatgg attagttgca gtagttcttc cgtttaagcc gttagaaatt ttgaatattt
  1054021 cgcactcaca gcggcaagcg cgtactcatt ctcgatgcgc tctcgggcgg tgcgcgcata
  1054081 gcgcgcgtat tctgcttcgg acagatcgag gaaggcgcgc attgcctcgg cgagagcctg
  1054141 cggattgcgc ggcggtacgg cgatgccggc ccttccggcg acgaccgccg cgtcaccaac
  1054201 atccgtcgtg acgatcggct tgccgtagct catggcctca gcgatgacat tcgggaagcc
  1054261 ttcggtccgc gacgaaagca ccaacaggtc gatgcttcga tagaatgcag gcatatcgct
  1054321 gacctccccc cgcagatcga cggcgtgggc cgggaggccc gctttcgcga tcagttccat
  1054381 gacctccggg ttgtcgcaga ccagcccgtt gccggctgcg gaaaagactg cctgcggatg
  1054441 ggtcttcaac acctgggcgg cggctttgaa aaacgtcccg tgatctttct gcgggtgaaa
  1054501 gcggcccacg atgccgatgc gccgggccgc ccgcggttcg ggcgccgcaa gctccgggag
  1054561 ttcgaagccg ttgggtatga cgaccgcatt ttgatttgta tagccgtagg cgcgatgcag
  1054621 atcgagcgcg cgggcgctgt tgtagataat acccgtcggc cggcgcgaca gcagtttcgc
  1054681 ggccgcgatc gcaacgcgcg aactgcgcgt gagggaagcg ggatcgtcca gcgattggcg
  1054741 aacgttccag aaaaccggcg ccccgtgccg ggccagcccc gccgccaggc tcccggcgac
  1054801 catcgcgtgg tacatccagc agaggataac atcgggccgc tctttccgga tcagcgtcgc
  1054861 aagccgaaga atcgcgcccg gaagcgctgt cagcgatgcc gctgccagcg aaacatagga
  1054921 aactctcgga ttgtcggcga ggcggcggtt ccggtccgaa acgccgatca gcgaaaccac
  1054981 gatgatgcgc tcgtccgtcg atccgtgcag cagccgcgcc agcatcgttt cggcgccggc
  1055041 actcgcggta aaattggtaa tgacatgcat tatcatcgga ttgcctgtgt ttgccgcatt
  1055101 gcggcgcatg aagtcacgtc aatcggtcag atgcatgccg tcaaacagca ttctgttgat
  1055161 catgtgaacg tcgaacctgg tttccgcgag ttcccgcgac cgccttccca tctcctccgc
  1055221 caggtccggg ttctttgcga cagtggtcat cgcttccgcg agggcggcga cgtcacgcgc
  1055281 cttgaccacc aagccgtttt tccccggctg cacggtgtcg cggcagcccg gcagatccgt
  1055341 cgtgatcacg ggccgtcctg tcgccagcgc ctcgagaatg ctccgcggaa ttccttcgcg
  1055401 atagtaagag ggcagaacga aggcgttgca tgccgcaaga tatggccgca catcgacagt
  1055461 ggtgccaaga tagtcgagta tcccttcgcg cccccatgcg tcgatttcct ctcgggaaat
  1055521 tgccgtcgga ttgctgtcga aatggccaag cagctgaaat ctggcattcg ggaaagagcg
  1055581 acggacaata cgcgcggctt ctacatattc gacgacgccc ttgtcgcgca gcagccgggc
  1055641 gaccatcagg aaagtcggtc cgccgcgagg cggcgtcgag aacgcgaaat ggtcgagatc
  1055701 gactcccgat ccggagatca tcgtcggcga gagatggcca ctcagcatcc gataacgacg
  1055761 aatgtcgttc tcatccgcgt cgttgtagac gaagacgacg cgggcgcccc gcagcgctgt
  1055821 acgatatagc cggacacaga ggtggcgtat ggccttcgcc ttgagcgaag cgccggcagc
  1055881 ctctgagaat atgtggccga ggcccgtgac gagaaagcag cgttctctaa tacccagcgt
  1055941 cctcgccgca atgccggcat agatgatcgg tttcatcgtg tagggaagga caatgtccgg
  1056001 cttcagccgg gcgaagtgtc gccgcaacgc ccaaaaggtc cgcaggtcct ccagcgggtt
  1056061 gaggccggtg cgcgccatcg ggatccggat aaagcgcacg ccgatctgcg caagctcctg
  1056121 ctcgacccgg gcgtcatgtt caggagcgaa ggcgatgacg tcgtgcccgg cagcgaccag
  1056181 ccgcttcagc aattcgagcc ggaagatcac cagagaggct gtcaagctgg cgacgacggc
  1056241 tatcacgcgc ttctgctgcg gaaaacgtgc cgcgctgccg cgtcctgccg acccttcggc
  1056301 aatgtgctcg gcttcggcgc gcggaacctt ttcaacaagt gtcaattccc cgtctccccg
  1056361 tttttcggtt ccaccgcccc gagcggtggg ctttagacta ccaactgctt gcctgcatgc
  1056421 accgcgtgag gagcatggct tccgatcggc gggcgtgttg caggaggccg cgccttcaga
  1056481 tgggccgacc ctgaccaccg tcgttcagct gccgggcgat cggagctccg caccgtagct
  1056541 ggcttctgat tttcccgcct tggccttgac acggttcttc gggcgtagcg aagcgcgatt
  1056601 tcgcacagcc atcttgagat cggcctcgtg ctcgtaccgc ggcagcaatt cgcgcatgac
  1056661 cgatacgacg gcggcctcgt tgcctcgttc cgaatggcgc tgaagccgcg caaacgcatc
  1056721 ccgcagcgtc ggtagaggta tggcctcggg caccgctccg agaacgccgg gcaccggcga
  1056781 gcttatgcgc ttgtcggttt cgtcgaacag ctcctcgaag agcttctcac cgggtcggca
  1056841 gccgatgatc ttgatctcga tctcctggtc cggcgtgaag ccggcaagcc ggatcatccg
  1056901 gcgggcgata tcgatgatct tgatcggctc gcccatatcc agcacgaaga tttcgccctg
  1056961 accgagctgc ttctcgaagc cgtaggcgga agcctgaagg gtgagttcca cggcctcgcg
  1057021 gatcgtcatg aagaagcgtg tcatattcgc gtcggtcacc gtcagcgggc cgccacgggc
  1057081 caattggcgt ttgaagagcg ggatcagcga gccgctggaa cccaacacat tgccgaagcg
  1057141 gacagtcata aatcgcggac cgagaccggt ttcgaggccg tgcaggtcca gcgcctggca
  1057201 gtagagttca gcaaggcgct tcgtcgcgcc catgacgctc gtcgagttga cgaccttgtc
  1057261 cgtcgatacc tggaccattg cgagggtgcc gtatttcttc gcggcgtttg cgacgttcat
  1057321 ggtgccgacg acgttggtga gcacgccctc gcatggattg agctgcacca tgggcacatg
  1057381 tttcagcgct gccgcatgaa agacgagttc gggccggtgc cgctcgaaaa tctccgccac
  1057441 ccgttggctg cggcgaacgc tgcaaagata gctggaccgc gggacctccg ggaagctttc
  1057501 ggtgagggtc atatcgatcg cgtagagatt gtattccgta ttgtcgataa ggacgatctc
  1057561 cgccggatcg cacgcggcga cctgcgtcgt cagctcgctg ccgatcgagc cgccagctcc
  1057621 ggtgatgagc acgcggcggc cgcgaacgag ccgatcgatc gcctcccggt cgagcgccgc
  1057681 ctgtgggcgt tccagaaggt cggtcaattc gatagagcgc agctcgtagg ggttatcgcc
  1057741 tttggcgcgc ttcagctccg tcatctggga caggcgcgag actgcaattc ccaggcgctc
  1057801 ggcggatctc agcagagcgt cggatgcttc ctcgccaaaa gccgcagggg cttcggtgaa
  1057861 gacgatgtgg cgtggctgtt tgttgagcag ctgcaattcc gcaaccacct gttcgaagtc
  1057921 ctgaatccgg cctgcgatcg gaacgccacg caggctcatg ccgatctgat cctcgcttct
  1057981 gtcgaggcac gcgacgggca cataggtggc attgggatcg cgtgcgagcg ccctaagata
  1058041 gaggtctgcc gcgtcgctcg cgccgacgag cagcagcgga attcggtcat cgccttgggc
  1058101 gtccttgttg cggccggact tgaaaaccgg gcgcctcagc gaaagctcct cggcccggaa
  1058161 gctcagccgc gcagccgcca ggaaggcaat gagcaggagc gactgcatag ggacgaccgt
  1058221 gcgcgggatg tcggtgagtc tggtcgaaaa gaacagcagc gtgacgagca gcagtgaggt
  1058281 cagcaaaacc gcccgaagaa tggtgaaaag gtccgagatc gagccatact tccagttccg
  1058341 gctgtaaagg cccgagaggg ggaagacgaa tgcgcatatg gcgagatact gcgctccgga
  1058401 ccagagtagc accgaggcgg tctccggccg tgcggagagt tctccggggc cgtagcgcag
  1058461 caacaatgcc atggtcagtg cgacgccgac cgaggccagg tcggtgagat agagggcagg
  1058521 gtatttctga acgctcctga cggctcccct aatccgtctg aagccgatgt caagcgcagc
  1058581 tccgcagaac gcccacagca ttccggccga tgctctgttg cgccactctc ttccccttat
  1058641 cgacggtaac atcaggaaat gattacgaac tgccttcgcg gcggcgtgta tacgctgcat
  1058701 gacggcccct tcctaaaacc tttgagccta tcgctccgcc gaacgacgaa cgcacgaccc
  1058761 ccaaagttct atggtggcta agaacagtgc gtctgtagtg tgtctcttcg gccagttcga
  1058821 aaggctggat aaatgaattc aacaaaaata ggcgttcgcg atcatgctaa ccgcaacgca
  1058881 aaatttcttg gcattttcga atacagtaat aaaaaagcac gtctttaaga ggttgtaaac
  1058941 agttttccag taatgcccca attatagttt tctactattc ttatgtgctt taatggcgat
  1059001 ggcggccata tggcgaactg cggttggaaa cgtctgcgaa gacgcgaaag gtcaggcggg
  1059061 gacctcgcct atgcggccgt cccgccgagc ttgccatgaa ttggcggtcg tcgttccgac
  1059121 gcccatttcc aggatgtcgc ttcgatacat tccgcatctc cgcaaagcac gatgaagccg
  1059181 cgctcggtaa tggcttgaat ctgacctgtc aaaccaatga accggctgga attctcaacg
  1059241 gggaccgcgg catcgatccg aattttctgc ccgttgtaga atgtgaaggc acccggataa
  1059301 ggggctccga ctgcgcggat caggcgcaat atagaggcgg cggactgacg ccaatcaatc
  1059361 aagccatctt ccgcggtgcg ttttgcgcaa tagctcgcct ccgcctggtt ctgttcagcg
  1059421 cgggcggcat ttccggcttc gacctgtgcc gcggcctcca cgatcatctg agccaggttt
  1059481 tcagtgtgct tggtataaag gctgcgggcg gtttcgtcgg gatcgaccgg aaattgccgc
  1059541 tgcaagagga taggtcccga atcgacgccg tcgtccagcc agaagagggt cgagccggtt
  1059601 ttctcttcgc cgcggagtat agtccaggga atgaccccgc ggccgcgcag acgcggcaat
  1059661 gccgccggat gaaagccggc ggtgcccaca cgcgcgatct cgcgaaatgg acgccggcag
  1059721 acctgcgacc agcctatgac gagcgtgaga tccggggcga ctgctgtaac ggcctccagc
  1059781 gtctccggag cattgatatc ggtcgaatgg tggaccgcgc ttccggctgc cagtgcgagg
  1059841 tttccgaggt ccacaaaatc agaatgacgt cccgccgctt cgggcggaag cgttatcaca
  1059901 agcgccggag ggcgccccgc ctttatgagt gcctccaagg cgattttgga gctttcgacg
  1059961 gcgcctacaa agacgatacg catgatcaca ccaacaaagc tgaaaatgaa aatgaacgtc
  1060021 tgccgccgag ttggacggca taaattgtga ggtcaatatc ggcccatcga acacaattat
  1060081 ggcgaggaag tctagggcat gttgctgaaa atcgatcagt atagagacac gccgcagtgc
  1060141 cacggcgacg ttcatgctgc ttagagtggc acggcgctgt gcaatgctgt agtcttcgtc
  1060201 cggttgaagg tggaaaatat cgttccgcca gctcacgttg caaattgctg cgccatggaa
  1060261 attatgatag gtcttgcttt tagcggacga gctcttgcgg ttgcgcagtg ttttccgcgg
  1060321 tcattttata agattgtaat aaagcgcata agacgacgcc acttggcggc agatttttaa
  1060381 gagggcgaca ccagccctgg agcgagacga attttcaagt ctcaaaaatg ttcctttttt
  1060441 ttgagtggac acggatcgtt acgccatgac cgtaagtgcc aaagaatttt attcattgag
  1060501 ttccaacacg attgatctgg tatcggaatc agcctttttc gccagactga agatgcgcaa
  1060561 tgggaccttc aagctgaccc agccatctcg gttccgggag ttggaggtcg catttcggcc
  1060621 gttcatcgcg gagcgggctg cctcactcgg ccagatcctg gatgtgggtg tgtccaccgg
  1060681 tttgacgaca gtggagctgg ccaagttcct cgaaggctgt ggcgccaagg ttcgcattac
  1060741 ggcgaccgac ctcttcgtcg aggctcacat cgtcgaattt gctcccgggg ttacggtatt
  1060801 ctgcgatccg gagggatggc cgctgcagta tgatctgcgg ggattgaccg ttcgtccatg
  1060861 gatcagaagg ctggactatg tgacgttggc gttcgcaccg ctcctgctgt ctcgtttcct
  1060921 gttgcaaccg cgcctgcgtg cccggatacg ggcgggcaag agcagacagg tgcaaatgat
  1060981 cacccgatcg ttgcccgaca acggcaagat aagattcgtc gagaacgaca ttatgagccg
  1061041 gtcgcaccac ctggtcgggc ggttcgacct ggtgagagcg gcgaatatat tgaatacgaa
  1061101 ttacttttcg ctggaccaga tccggactgc aatcgagaac atccattcat acctaagcgg
  1061161 ccccggtgca ctggtcgtgg tgacccgcac gaaccgcgca ctggaaaatg ccggaactct
  1061221 gttcgagctc cgtgaggatg gttctttcgc cgcgttggag cgcgtcggcg gcggctccga
  1061281 gatcgaaaaa cttcttctgg acttccgggc atcgtgaggc ggagcttcaa gccgcggagc
  1061341 ggaacttcac ggcttcgaca cgaaatgtcg ccacgtcttt gcggtcggcc aaaagtgcca
  1061401 aagcatatta gcaaatggaa ggctttctga tgccctcgca accagttcgc atcgcttata
  1061461 ttgcaggtta cggacgcagc ggctcgacga tactcgacat tgccttgggg cagcatgctt
  1061521 ccgtgatggg ggcgggggag gtaacgtcgc tgacacgcca cgtatggcgc cacaacgaat
  1061581 attgtgcttg cggcaatgcc attcgtgact gctcgttctg gagctcggtt ttccaggatt
  1061641 ggtccaccag cggtggttcc ggactcatgg aagaatatag cggccttcag gaacggttcg
  1061701 aaggcctttc catgctcatg cgactgttga gcggcatcgg cctcggcaag caattttcgc
  1061761 tctacaccct tcatacgaag cgcctgctcg aagcgatgca cgcgcactct ggacggcaga
  1061821 cgatcgtcga ttcctcgaaa ctgccgggga gagcgatggc gatggcgcag atccctggaa
  1061881 tcgacatgcg ggtcattcat ctggtgcgcg acgggcgcgg cgtcgcgtgg tctttgctga
  1061941 agggctatga gcgcgacgcg aaatcggggt tgcagaagga aatcaggccg aaatccgtgt
  1062001 tcaggacggc cgtgcgatgg agcatggtca atcttgcggt cgaatatctt tcgcggaaat
  1062061 taggacccga aaaggtcatg cgcgtcagat acgaggattt tgcgtctgac cctgttgccg
  1062121 tcatgcagaa aatcgggacg tttctcgaac ttgaccttgg cccggttggg gcctccctgc
  1062181 agaagggcga ggtcatggcc acgggacatc aggtggcagg gaaccgattg cgcatgaatg
  1062241 cgtcgatcgc actcaacaag gacgaggcct ggcggacgcg gatgccggcg cggcagcaga
  1062301 tttcttttca gcggctgggc ggctggatgc tcagacgcta cggctatctc tgatcgatgg
  1062361 cgcgtgatac ctctacgaaa gctgtgggca tgtctgccgc ggcaaagggc ggttctggcg
  1062421 tgcctttgcg acggttcagc attcgagaat cctgtacagg ccgtttcttt cggcagacca
  1062481 tcagtttcag ctttgactcg gcggcacgag agaatgacgg caatcaataa gtcgcaggac
  1062541 gtaagggcac ttggtttcac gatagctcac tgcctgatat tgggaggggt gctctgcgga
  1062601 tcatggctcg cctttccagc gaaaacggcc gctcagacca cgttagccga gcctcttcca
  1062661 cctaagcttc cggacggcag gcaacgcgcc ttccccacgg ctgaaggctt cggtgccggc
  1062721 tctctcggcg ggcgaggggg caaagtgctc tatgtcgtca acaccgacga gtcaggcccg
  1062781 ggttcgctgc gcgcgtgcat cgaagcctca ggaccgcgcg tctgtgtctt ccgaacgggc
  1062841 ggcaccatcg ttctgcgcga gaggtccttg gtcgttcgaa atccatttct gacgatagcc
  1062901 ggagagaccg cgccaggtgg tggcatcgcg atccgcaacg gcgacaagca aattcgccct
  1062961 tcaatcgaga tcgtgacaaa cgacgtgatc atcaggcaca ttcgccttcg cccaggccca
  1063021 catgccgtta gggcctgttg ttcgggcggg cttggaatgt attccgcggc cgccaaggac
  1063081 atcatgcttg atcatatctc ggccagttgg ggttctgacg agactgtcga ttcggaagat
  1063141 gcgagcaatt ttacctggca gtggggaatt gcgagcgaac cgctgctgcg gggcggaccg
  1063201 ggaaaaaaga accgtgcacg caacatgctg tttacgaagg gtggaaacat ctccgtccac
  1063261 cactcgctct ttgcttttgg ccagttcagg aatccgttga taaagatgaa gattcccgga
  1063321 gcagtagccg acgtcgtgaa caatgttttt ttctcgccaa agtggcaata cgtcctcagt
  1063381 ttcggcgatg aatggggcca tattcgtgcc aacgtggtcg gcaactacaa gatcgctgga
  1063441 gagaaccttc aaaacgacca tatggtccat ctcttcgatg agcgcggtgg cggccatgcg
  1063501 atctatgtga aggacaacta cgacgaaccc tatcgcacgc agcccgggca ggatgacagc
  1063561 ttggttctgg cggaaagcca aagagggtct gtttcgccac aggcgttcaa cgcagaggca
  1063621 gtccgagctt ccgggcctga aattgcttac gacgaagtcc tggcacacgc cggtgccaca
  1063681 aagccgcaac gggacgccat cgatcgccgc atcgtcgagg acgtcaagaa ccgccgtggg
  1063741 cggttgctcg cgaacgatcc caacgacgtt ggcggttggc cggagctcga tgccggtatt
  1063801 ccatatcagg acagcgacat ggacggcatt tcagatgact gggaggttgc caacggcacc
  1063861 gacccgaaaa atgccgacga cgcgaaatcc gaccaggatg gtgacggttg gaccaacctc
  1063921 gagagcttcc tccacttcat ggccggcgat accgctgacg ctgccagcca cgagtgacgg
  1063981 agattgttta agcgacgttc gacgggcggg tgatcgaagg tctcgccgag ggagcggtca
  1064041 aagtgtttac ctccgcgtcc ggccgttctt gcagtgcccc gttgccgcga tcgcgatgcc
  1064101 agcgtccagc cggaatgcgc ttggacgtta tgacgaagcc accatagtgg tggcgccgat
  1064161 ggatctcggg gttgacctga ttgatcacgg tgccgatcaa atgcgcatgg ttcatcctga
  1064221 gttgggcagc tgcttccaat agctgctctt ccgtcgtttt cccccaattg gcaaggagga
  1064281 ccacgccgtc aacaaagggg gccagccaag ttgcatcgcc ggacgcgagc accggtggag
  1064341 cgtgcagcac gatgaagtca tacccgcttt gcttcaggtc cataatgagt tcacagagac
  1064401 tgtcggagtc cagcgatctg aaaggctctg tcattacatg cgtcgcgtcg atgaagccaa
  1064461 agccgggcaa gttcgggatg gactgtacga tctccgtcaa agcggcgcga tttcggagat
  1064521 agcgttcgat cagttccggc gaacgttcca tgttcttcag ataagatatg ttgtgacggt
  1064581 tgaaatcgag attcacgaag gccgtgggac gaccatctgc cgccgcggcc gttgcaatac
  1064641 cccaggccgt tgaagcgttg gcgacgtcgt ggaggcagga tgtcgtcatg acaactcggc
  1064701 gtaactgcct cgcatccgaa tagcggcagg ccatgtaaac cgcccgctct gcttccgcgg
  1064761 acgtaacgtt gctccaatcc ggaatacatg aggagcgcct ggcgcctggc gacatcagat
  1064821 gcttcgggac tttcggcaca tagccgagat tgggtatccg cacgagttgg gtggtgcgct
  1064881 gtccgcttcg gacacgggta tcggtggttt ccagcaggag cgccaatacg ctggcgagca
  1064941 gcgtggaacc ggcgagggcc gctggtatga tgaggcccgg tttggggaaa gagggtgaat
  1065001 tgggaagctc cgctgtcgat acgatccgtg cgctgggctt cagggactcg gcctcgagat
  1065061 cggagagaat acgctggacc tcgtcttcga tcatgctgcg gatgccggct atctgggaat
  1065121 ccgcatcgat catctgagga tgatttttgc cgtacttggc agcaagctcg gccctgctct
  1065181 gcagcagacg ggcctcttcg ttgcgcaagg ttatcaggag cggctgcgtc atgctctgtc
  1065241 gaaggaaagc caccgcacca ccggtattga gtgcgcgttg cttgtccgcg acccgctcgt
  1065301 cctgcttgaa ttcgagcgac gcctcgacgt acaggctggc gatcgtattc gcgatctgct
  1065361 gtgcgagttt cgggttctga ttggttacga taagcctcac cgccaggctt tcgccggtcc
  1065421 tgctcacctc gaactgagac agcagcgcgg agatcgcgtg atcccgttgc gtctttatat
  1065481 caggtatgac tcgcgcggat gtagaggcac ggcggacgcc gatgaggtcc tggacatatc
  1065541 gcaggagacc ttggtcgctc gatttgtcgc cgcccggtgc gtaagggttg aaggttggat
  1065601 cattgacgag ctccaaccgg tccacgatac ggccggcgaa ttttcgcgat tgcaagacgt
  1065661 ccatctcggt ttccgcagcc gatcggtcgc gatcgatgga ggtcaaagcc gcatcggttg
  1065721 caaacggacg gacatccttt cgctccagca ccacttcgga gctggccgtg taggatttag
  1065781 ggatcgagaa agatgcaatt gcggacagca atgtgcagac gaaaatgatc gaagcgagaa
  1065841 accagaaccg tcgcttgact atcgcccaga gatcgaaaag tccgaccgtg gccccgccct
  1065901 gctgagcggc gaaatcgaca gtttctcggt ggtgagcgcg ggcagatagg ctgccatcgg
  1065961 gaacgaatgt cgtcatggaa acctgcaaaa tatcaaaaaa ttttctgtat tctgttacat
  1066021 tagtaaaatg tgtagtaagg cgcaataaat ttagcttgtg ccgcgataaa atactgcggc
  1066081 cgcagaatat gtgaactcta tcgggccatg ggcaagcagt ggcacacatg gtcgatcgag
  1066141 acgcccgatt aaaacaaagg acgttgttaa atctacaata ctccggaatt tccagcgcgg
  1066201 ccagctaaaa tcgcgccgtg gatgtactca agtgctgaaa acgccacctt tttcggcggg
  1066261 atttttagtg cggccgcgcg cttgagattg cgcactcccg tgttgcctcc gtgttcacga
  1066321 cgatacgcca gttggaggtt caaccacgcc cccgtgcggt gccccgcaat tgtgtaagcc
  1066381 ccagtccaaa acacagaaga actggcatgg tccagtatct cgcatacata tgcggattga
  1066441 agagagcgat cacgaggaag accaggattg ttgtaatcac cgccgccaag gcacgtttgt
  1066501 ctccgcggac ccttaggatc gcgaggctga gcagtacgcc gacaccggaa aacagcagcc
  1066561 aaccgataag ggcgagcaat ccgccctcaa cccagagaag aaggtagagg ttgtgaaccg
  1066621 gagcgctttg aacgcttctc tcacggaact gatcagcgcc gagcccaatg atcttgatct
  1066681 gctcttctga aattatatgg agcgcttcct ccatcagtgc tgctctcgaa aggaaggttc
  1066741 ccgcttcgga gatatcaccg gaggaaagcg cccccaaaac gcgcgtctga aaagttttgg
  1066801 gcagcatctc cttgctgccg aacagtgcgg cgccgccaac gacgatgctc aagccgagcg
  1066861 ccaggcgtaa cagcagccga ggcgtcgaga cgagggcaat aaagactgcg aggcaaagcg
  1066921 ccgtagaaaa tagcccgctg ttggaactgg tcaggacgac cgtgacgatg attatcgcca
  1066981 gggcgggtat ggcaagatag gattttgcgc gtcccgtgga ccagaagaac agcaggatcg
  1067041 ggagcgtcag ggcattcatc gccgctgcga ggttggggtt gcgcagcact gtggcgagcc
  1067101 gcttcccgcc ggtgacgatg ccctttcctt ctccaggcac atatccgacc gtataaaacg
  1067161 tgatgatacc gtgaatatcg atgagaatga cgctgaccag gaatatgccc gcgagccgat
  1067221 aggcttctct ctgatcgtca cggatgagaa tgatcatcaa aatcatgtat gcgaagagat
  1067281 attgccccat gacgatcagc ccgcgctgag ggctgccgtt gaagaggctg ccgagcatga
  1067341 tgccgaggaa gagcaggatg aatgcaacga gccagacgga cgttgcacct tcgagtggcc
  1067401 tgctcctgat gcggccggtg atcaagagaa ggaaaaggct caggcaaaag aagaaatcgc
  1067461 tgaacgtgaa gaagagctcg gaaaatcgca gagttgcgta aggcgccaga aaaacagcgg
  1067521 tataaacgac ggcacgttcg atcgccgcca ggtgaaggtt cgttctgctg ggttggccac
  1067581 caaaatgtag ctggtgtgcc gttctcattc cggtctctga cacgattgcc tcacaccgat
  1067641 tatcggatta ccccggtcac gggcctgcac ttgcagagcg ccgcattccg gttccaccga
  1067701 tcaggttttc gtagaccgat gtaattgcgt gcacgtggcg ttcgaaactg aaacgggagc
  1067761 ggacctcgcc acgcgccgtt tccacgaggt ggtcgcaaag tccggaattg ttgaacagtg
  1067821 ccaggcaagc cttggcgaat tcatccgggt cgtctgcggg aacgagcatt ccggttctgc
  1067881 catcttcgac cacctccgga ttcccaccgg agtcggccgc gataaccggt gtgcggagca
  1067941 acatcgcttc gacaagtgtt cttccgagag gttcattcac agccgttacc agcagggcat
  1068001 ccagtccggc gatccaggct tcgcccggat aacggaagcc catgaagtga atgcaatcgg
  1068061 caacccccag tgcctcggcg cgggatctcg ccgcttcgtc caggccattg agcgcatcgc
  1068121 cgaaaaacag gcccgcaact ttggtctcag gcgatagccg cttcaaggcg gctatcgctt
  1068181 cgacgaagag gatcggccgt ttgcgcgcaa ccagcgttcc gacatagccg aggagcttgg
  1068241 tgtcgggtga acatccgatc gcggccagca cgttgttgcg agcttccact cgatcgaacc
  1068301 cgtccatttt catgacatcg aaggggctgt gaacgacgct gcatttgccc gcggccgaga
  1068361 aaaatcccgg ccggggcgat gcgaatttcg acacggcaac cagccggttg ggcagccagg
  1068421 gggccacatg gcgcagaccg aacgaagtag cgtcgccccg atggtgccaa aggtgtttcg
  1068481 acccggcaat ccgcgcagca agaccccaga taagatgcgt gcggccatca ttcgtgtgta
  1068541 cgatcgaggc atttcttgcc cgcagaaact ttacaagccc cggaaccgtg cgcacgacat
  1068601 tgaccactgc ggcgccgttg cgcggagcgg cccgctcaag gcggttcaaa acgggagcct
  1068661 cgacgaagcc gatgccttcc cggcggaaca attccgcgac cggtccatcg gtatggtgca
  1068721 gcacgaccaa tggcacaaag cgatcccggg ggagatttcg tatcagacca agcgaggaca
  1068781 tgtggcttcc gccaacgagg tccccgatga agggaaagca cacgaccgcc tgatggccgc
  1068841 caacgcttac gccgggcgct tctgattggc gaagatcaac tgctgcagac gataccatac
  1068901 cgtggttccc aaaaaactgc tgagcgctcg acagccgcgg ccgcgccgga cgtcatttct
  1068961 cgaggcttct gtttctcagc cagcttgtca gatcgcgtcc gacaagagcg ccgagttttt
  1069021 ccgtttcaag tgcgaagtaa tcggtcatcc gctcgcgcag gtcacggctg agcggtgcgt
  1069081 attgaagctc cccggcgatc agcgagcgca gtttcttgaa gccggtattc tgccggaatg
  1069141 gagcagcgac gggcttcaag gggcgcagga gccggcgcag cgtcggattg acgaccggtt
  1069201 ctgatttgtc cttcaccttc tttgcaagcg gctttagcgg gacatcggct tcaagcttga
  1069261 ggaagccgcg gacgcgggcg acctgggcgc cggcatcgac cttcaggtcc tcgtacagga
  1069321 gcaccagaag ctgctccaaa gggaagcggt cgagatacgc ctgcagctgc tggaaataga
  1069381 ggccgccatt caggaagcgc ccgcctgccc cttgtcgtgg atcgagatac tgggcgatgt
  1069441 cccgcccgac ttcggcgcgg cgataaagca tgcagtagtc ggaataggcc cggtcgactg
  1069501 ggttgcgaag ctgcgctatc aggtgggcct ggggcagctt ttcctttatt ctttgtgccg
  1069561 cctccggcac gtccatgtag gaattggatt tctcgccgcg cagccgtcgg tgctcctgcg
  1069621 ctgcgaagtg ctccagatac cattcgtcgc cgcggtcgta gtaacggctg aaatagtgca
  1069681 gttcgggatc gggcatgaat atgccgggat cctgctgcag agattgctga agccacgtcg
  1069741 ttgcgctttt cgtcgcgccg atgatcaaaa aatcgatgtc ccgcatttgc atctttggcc
  1069801 ctttcgtcta ccgccacgca aggcgattac accgaaaaca acaggtgcgc cgccgccttc
  1069861 caatgggcgt ggatcctggg gtcaaacact gcttccgaaa atgctgcgcg aaaggatgtg
  1069921 ccgttacgtc tcggctatac gagtaaatgt atcggttgat gtttcctggc gaagcagcag
  1069981 aatttgcgcg aaaaaatccg gaaaagcgac ctcaggttaa gtgataatct ggcaatttga
  1070041 aatgaatgaa atctatcgag ggaatttcac agaaaaacgt cgtggaggca agatgcttct
  1070101 ttgcatttgg cgatcaaggc cctggcgccg gggtgcgacg gtagctcagc atcatcgttg
  1070161 acaaccagat cgaagccatg acgatatgag cgacattcgc tcccatggcg cccatggtcg
  1070221 gaatgagagc gaatgcagtc gcatgaaaac cgatcgcggc gatcgtgacg ctgcgcaata
  1070281 tctcgttctc acgtcccatt gccagaagcg ccgaccggat gacggcgccg cacagggtca
  1070341 tcgtgacggc gatcgactgc acgatcacga gtgggccggc ggccgcgaac tccgggccgg
  1070401 cggcccagga gaggagaggg ccgataagga gatagaggcc gccgatcaga aagaggccgc
  1070461 aggcgaggag aagcgcctgc atctgtgcga ctgcccgatg aaaggcgccg agcgccttgg
  1070521 cggcccatgc ccgggcaagt tccggataaa ggacggcctg tacctgcacc ccggcctgct
  1070581 gcgcgatgcg gccgatgcgt ttagcgatgt gatagagtcc ggcggaagtc ggatcggcga
  1070641 gatagccgac gagcagcgtg tcgagctcgt tggcgctcga acggatggtg agcgacaggt
  1070701 tcgccgagat cgcaaacttc caaagccccg gaaaccgggc ggtaatgccg cgaagcgggg
  1070761 cgctcagcag gcccgagagg ataccttgcc ggcgcagttc ggccagcgcg aaaagcacga
  1070821 gaacgagggt gccgatgatc tgcgccgaca tccagatgag cgtgaattcg aacaggccgg
  1070881 cgcccgtggc gacgccgatg gcgcaaagag ccaccctaag gacgcttgtg gcgacctggc
  1070941 cgtaggcgat cgccatgaag cgcccgtaaa ggcgcaaaac ggccgtcggc atgccggata
  1071001 cctggaatgg cagcaccgtg cagtagagta tggcaaggct cgctccgtcc tccgagatcc
  1071061 cgagccaggg tgaggccaac aggatgaaca ggacggcgat cagccatccg gcgagcgccg
  1071121 cagaaacatc gagcagcagc ccgaatttga gcaaggactg catttctttg aagtcatcgg
  1071181 cgttatccga gagcgagtgc gcgccgtatt tgatcagcgg ttgccaggac tggaagctta
  1071241 cgatcctctc gaccgcgcgc gtataggaga aacacagcgc gagaatgcca tagcccgccg
  1071301 ggccgagggc cctcgccgtg agggcaaagc cgatgaggcc gatcaccgag ctcagaatgt
  1071361 ttccggtgag cagatgcgca atgctctgca ggcgctcgag cagcgttctc tctcgactga
  1071421 gaatttgtcg caagccgccg attttcttga aaagcttttt tcggaacgcc actggaaccg
  1071481 cctgtgattt aaaagacaat gtaataagca aaggtcatgt gccaagccca ctgtcgcaaa
  1071541 ccgctcccgg cggtcgtcca caaggacttc tcgttggcta aatggatatg tcagaggaag
  1071601 agctggcgaa atcatgccga ccactttgcg aggccgcctt gtgcacggtg agccgatctt
  1071661 tcccgccaac gctcctctaa aaacgcaata agtttataca acagtttgaa atattaagcg
  1071721 atcttcacca taatacgggg aggctcaagg atcaaattca acaagaaggc cgcgattagt
  1071781 taaaaacctt tgacgtgata gcgcgtggaa gaatatagtc gcccaatatt ttttggtagc
  1071841 gttttcttta ttcctttttg gaggctgtga gatggggatt tcaccggccg ttttcggaac
  1071901 gattttgccc cgcttaatga atggggcgtt cctgctgctg atggttctat gggtgctcgc
  1071961 ctgtgcgatg ataggagcaa tgccggctcg agccagtgat taccggctta acactggaga
  1072021 tgttctgacc ttcgacttcc ttgatgatac agagttgccg gtcaccgcga ccgtttcggg
  1072081 cgaaggcgaa gcacaatttc cgctcattgg cgccgtgggc gtcgtcgggc tcacggtgcc
  1072141 ggaggcgctg gagaggcttc gcggcgagta ccgcaagcgc gaaattctcg tcgatccgaa
  1072201 gatctctctc gatatatcca ccttccggcc gatcttcgtt ctcggagaag tcaagacgcc
  1072261 gggctcgttt cccttctaca gcgggttgac ggtcgagcag gccgtcggtc tggcgggagg
  1072321 catgcaggtg gttgcggcaa acgcctcaga caggatcatc gcacgggcgc gtttgcgcgg
  1072381 ggacatcgag ggtgctcgcg ccgagatcgt gcacgaagcc atctatgccg cgaggctcgt
  1072441 ggcgcaattg aagtcctctg acaaaatcga cctcgccgac gtccccgagg tcgcgcgcga
  1072501 ctatgtgacc agcgtgccgc tcgatggtgt cgtcgagctc gaagaaaaga tcctgaaagc
  1072561 cgaccttgcg gccaacaagt cgcaggcgca gatcctgacc gaaggtatcg ctcaggccga
  1072621 gggtggaata gatattctga accaactggt tctgcagcaa aaggacgtgg tgcagaacag
  1072681 caaggaggat gtggaccgta ccgctacctt gcgcaagcgc ggcctgaata cagagagcga
  1072741 cctgtcgcgc gccgagaaca atgcctcggc cgaacaggcg cagcttctcg agactttcgc
  1072801 cacccttgca cggtcgcgtc aggaaatgag tgaattgaag ctgcaactgg cgaagcttgc
  1072861 ggccgaccgg gagaaggata tcctgaccca actccaggcg cgtgagatcg cgatcaaaaa
  1072921 gctgatttcc caacagcact ccgccgaaga acaaattctc ctcatgaccg ctgtggccga
  1072981 agacgagtcg aagaagaagc agatttccta tacctacgag atccgtcgaa acccggttgg
  1073041 cggcacgccg gccagcataa aggcgtcgcc cttgactgaa ctcgttcctg gcgacgtgct
  1073101 gacggtggct attgccggaa tgtaagacct tatttcagaa ctttttgaag acacgctcta
  1073161 cgccatcgtg cgccaaggga atattgagtt gaaaaccttt agagaacctg cggctgtcag
  1073221 cttgggcctg cctgcctcct tgggatatta tcgtctcaag cgtctcctcg attgtctgct
  1073281 tgccggaacc gttttcgtcc tgtgcctgcc gctgatggcg gcaaccgcgg tcgtggtttg
  1073341 ggcaacgctc ggcttgccgc tgtttttctc ccaggcgcgg gccggtgtgg aaatgcgcgt
  1073401 cttcaccgtt gccaagttcc gaacaatgac ggatgcgcgc gcccccgacg gtacgcttct
  1073461 gccggacgat atgcggcaga ccgcgtctac cgcgctgttg cggcggctgc gcttcgatga
  1073521 gttgccgcaa cttattgcgg tcctttgcgg ccatatgtcg atggtgggcc cgcgccctct
  1073581 tcccttggcg acggtcgcag gcttcggcga gctcggccgc atgcgctgcc gcgtcgctcc
  1073641 gggcatgacc ggctgggcgc aggtgaacgg caacacgcgg ctttcggacg acgagaagat
  1073701 cgctctcgac ctctggtacg ttgctcatgc caatctctgg ctcgatgcgc gaattcttct
  1073761 gctgaccgtc aagacgctgg taacaggcga aagcgtccac gcaggacacc tgcaggaggc
  1073821 cagggaattt ctttcgcgtc gccttggcgc agagccgcca aaggcgtgat gcggtggatg
  1073881 ggcatgcgcc gaaggcgcca ggattttcga tgaggaggtt tcatgggtag cggacaggtt
  1073941 tctttcgggc gtactcttgt cgtcgcaccg catcccgatg acgaggtgct gggcgcaggc
  1074001 ggtacgatcg caaggctcgc ggccgagggc gaagaggtct tcgtcgccgt cgtgacggag
  1074061 ggaaagcccc cggccttcga cccggaggca acggcccgga tccaggccga agcaaggaaa
  1074121 gcgcatggcg tcctgggcgt gaaggagacc atatggctcc ggctgccggc ggcacagctt
  1074181 tcagaaacgt cgcatgcgac cgtcaatgcc gccttgctcg agcttgtcag ccggctgtcg
  1074241 ccgcaaaccg tgttgctgcc cttcgtcggc gacatgcaca tggaccatca gttgacattc
  1074301 atttccgcgc tggtcgcctg ccggccgcat caggcagagt ttccgaagct cgttctcgcc
  1074361 tacgagacgc tgtcggaaac caactggaac gcaccctatc tgtctccgcc cttcgtgccg
  1074421 aacgtcttcg tcgacatcag cgatcatctc gaggccaagc tcaacgcgat ggaaatgttt
  1074481 gcttcacagg tccgccagcc gccgcatgag cgctcgatcg caacgctcaa agcgctggcg
  1074541 acgttgcgcg gtgcaaccgt gatgcggaaa gcagcggaag ccttcgtgct gatccgtcac
  1074601 gtcgtttagc cgatacggca acacacgggg attactcagc ttgttgcgat agaaccaatc
  1074661 cgaattggag ggacatatgg gacgctggcc ggtttacgat gaggagcaaa tcgaggatgt
  1074721 cgtgtcgatc cttagatcgg gcgaagtgaa tgcctggacg ggcccgcacg tacgcaactt
  1074781 cgaggctgcc tatgagcgct ttctcggcgt caaacatgcg gtggcgctcg ccaacggaac
  1074841 ggttgcgctg gacctcgcgc tgtttgccct tgggctcgcg tccggtgacg aggtcatcgt
  1074901 aacgccgcgc agtttcattg cctcggcctc cacggtgccg atggcgggcg gcgtcgctat
  1074961 tttcgccgat gtcgatccgg acagtcagaa catcactgct gaaagcatca gggcgaagct
  1075021 gacaccgaag accaggggcg tcatcgtcgt gcatttggcc ggctggccct gcgacatgcc
  1075081 tgccatcatg gcacttgccc gcgagaaggg tctttgggtt atagaggatt gcgctcaggc
  1075141 gcacggggcc gaaatcgatg gccgtccggt cggcagtttc ggcgacatcg cggccttttc
  1075201 cttttgtcag gacaagatca tcaccaccgg aggcgagggt gggctcgtgg cgatgaacga
  1075261 tgaggaactc tggaaaaagg cctggagccg caaggatcac ggcaagtcat atgacgccgt
  1075321 ttacaacaga gagcacccgc ccggtttccg ctggctgcac gagtcaatcg gaaccaattg
  1075381 gcgcatgacg tcgatccagg ccgtcatggg atcgcgtcaa ttgcagcgcc ttgcggagtg
  1075441 gcgcagcata agggcgcaca atgccgctat tctcgccaga gcggcggagg agatcgaagc
  1075501 cttgcgcacg cccctgccgc ctcgggggac ccagcatgcc tggtaccggt tctatacctt
  1075561 cctccgaccg gaacgcttgc ggcccgactg gacccgcgac cggatcatcg ccgagatgaa
  1075621 tggtgccggc gtggcatgct tcagtggcag ttgctcggaa atctacctgg aaaaggcctt
  1075681 cacggacgcc ggcatggcac cgccgcagag attgccgaat gcgcgggaac tcggagagac
  1075741 gagcctggcc tttctggtcg accccgcgca cgatacggcg gcaatggaga aggccgcgca
  1075801 tgtcctgcgg gaggtgcttg ccagggcgag cattgccatg ccatcccgca agcgtggcta
  1075861 gacttagact cgatcacgtt catgtcttta gggcgggtcg gtctaaagac atggacggta
  1075921 cgattcgaat aagttgagac gcggaatgcg cgcggaaaac cgcatacatg cacgattcag
  1075981 actgcgggtc accgcagtct gaacgaggcg gacagcgaag ggttctgtcg gccgaccgga
  1076041 atcgcggaaa ctggaatgcc ccggagcaat ccgggtggaa cggttcggac gtgcgtgctg
  1076101 tggcgtatca gacgttcagt ccggtatggc cgacgagacg tttggcggcc gccgtgagat
  1076161 cgactgcgca caggcgttcg acttctgcga cctgtgcctc gtccagatag tcccggaatc
  1076221 cgccggcctt gccgcggcgc atgcgaagac tttccacgtc gcttcgatcg tagtcatgtg
  1076281 ccggaatgcc ttctacccgt tccctgtcct gcatggcctc gaaccggccg gccgccaccg
  1076341 ctgaccgcag tgccgttcga tcgatcgggc agcccaggaa gccgagcacc gcttcggttc
  1076401 gtgcttccgt atcggcggat aggccctcat agctcaggac gaagtgcgga cggctggata
  1076461 aaccggctgc ccagcgattg agataatcga tcatagcggg catgccctga tcctggtcct
  1076521 ttatgaactc ggtaatgctt cctgcgaaac ggtgcttgtg ccgggtcgca tggaaataag
  1076581 ccgagacgat aacatcgcgc gggtccctta ccatcatgat caccgggcgc cggaggaaca
  1076641 gactagccct gtagtccaga tggctgacaa ggatagtcgg gatggttttt ttcgtctcgc
  1076701 ggaagcggta gcctggcatt ccccgcaccg ggtcgagatc gaaattcggc acgatcgaga
  1076761 acatgttgtg aagatctatc ccttcgggca cgccggaaac cgccccgaga taatgggaaa
  1076821 gaacgtaccg gaaccatgtg cggcccgatt tcggatagga gatcaggaag caatcggatt
  1076881 tggcggcgta agtcgtgagc cgtactcgct tctccactcg acgccatatc cgcctgagaa
  1076941 tgctagccat tgtcgttccc tcgaaattga gatcaccggc gcgcaaatga cgcgcggtca
  1077001 aatttagttt tgaagcttta ccggtgcgat aaagactttc agaatgaaat ctactcgccg
  1077061 tttctcaacg ggatttttga tgcaaataga aaactctttc cgtcggcagc ggtcgcgcgt
  1077121 ttaatgcgct attgattctt gaaaacaatt aaataaactt gtcgtgcgga tcgttccgcg
  1077181 gctggcaatt tcatgcattc gttttagcaa attgaatatg aaatgaaaaa cacgcactct
  1077241 gtcaatgacg tgcttgctta gggcgttatg cgcacccgta aacattccta tcagtagtgg
  1077301 tagaaattgt gatggttggc atcacgaatg gcggaatgga ggcaccagat gacgtccctt
  1077361 gggcgaagag aaatcgttgc tgcaaaggca gccatcatgc ctgtcggtgc cacgcgcggg
  1077421 cccgcagggg agggatattt cgaaatgagt gaaaattcga actccccggc tgtcgtggct
  1077481 ggaaacatgt ccggggcccg tgtgacgatt atcctgccga gccttggggc cggcggcacc
  1077541 gaacatgtgg taaagctggt cgccaaccat tgggcccagc tcggttgcaa ggtgacgctg
  1077601 atcacgctcg aactgcctca tgccagacct tattacgaat tcgatccgag gatcgcgatc
  1077661 gaacgtctcg gtttgccgcc gcagcaaggc gggaagattc gggcgggcct gctcgtgctc
  1077721 aggagaatct accgcctgcg ctctgcaatt cgccactcgc agcccgattt cgtcttgagc
  1077781 ttcctgaccc ggaccaatgt actgacgctt cttgcaacga tcggactgcc ggtgcctgtg
  1077841 gtcgtttccg agcgcaataa tccggcgctg cagcctttcg gtgtgttctg gaaatggatt
  1077901 cagcgccgtt tgtatccgcg cgcattcggg ctcgtgacta tgacgagggg cgctctcgac
  1077961 tattttccgg agaagatgcg cagccgaggg tgggttatcg ccaatgccgt cgatctcccc
  1078021 ggcgaatggc agaagagacg cggcaacaat atcctgaccg ccgtcggccg gctgacgcga
  1078081 cagaaaggct tcgatctcct gatcgaggcc tttgcgagga ttgcctcgag gcaccccgaa
  1078141 tggaagctcg tcatctgggg cgagggcgac gacaggaagt cgctcgaggc cctgcgggat
  1078201 gcgttggata tgaccgacag ggtggagatg ccgggcgtga cgcaaaggcc cggagtgtgg
  1078261 gttgagacgg ctgacgtatt cgtattgtcg tcgcgctacg agggatgggg catcgttctg
  1078321 ctcgaggcca tggctgcagg gcttcccgtg gtttcctttg catgcgagtg gggcccctcg
  1078381 gacatggtgg agcatgggga ggatggactt ctcgttccca gcaatgacgt ggatgctctt
  1078441 gccgaggcgc tctccagggt ccttgccgac ggcgagctca gaagccgtct ggctgcaaat
  1078501 gcagaggcga gcgccaagag atacttgccg gatcgcatac tttcgcaatg ggacgcagtc
  1078561 gccttatcgg ccttgaaaca tacggctcgc gaccatgccg caacggcttc ggtcgtcgga
  1078621 gccggctcgg cttgagctcg gacaagcccc ggagtgctgc acggcggcat tgcagggtga
  1078681 cgcataggtg ttgatatgcc actatcgccg ccgagtggac tggcgatgag aggggctatc
  1078741 gcatgggtac aggtgtgggg cgtgtcgtag caggcttttt tctcctgctg atctttgctt
  1078801 gtgcgacgcc cacgatggct caagagccgg cgacgacgcc accgggcaag gttcagcaac
  1078861 tcatgcagtt gctggacgac cccgaggttc gtggatggat cgagacgaaa aagaccgctc
  1078921 cggagcaagc cgtcaagcca tcccaaggtt tcgctgcaaa ctggatcgcc gccatcaggg
  1078981 ggcacctttc cggtcttgtg gccgcggcgc cgcgggtgat gcccgaatgg cgggcggcgc
  1079041 gggaacgcgt gtcgggcgac atgcagcgcc agggaagctt gccggtcatc tgggcgtttg
  1079101 cggtggtcct cctgatcggt tacggcgccg agttccttct tcgctatctc ctgcggcgta
  1079161 gcgccaaccg caacaatgcg caagggagcg gagggttcgc ggctttcgtt cgcattgcac
  1079221 cccttgtcgc tttcgcagtc gctgccgtcg ccgcttttgt gttcgccgat tggccgcgta
  1079281 gccttgaggc ggcggtcgcg ccgctcctga tcgcctggat cgtcgcccgc ctgctgattg
  1079341 ccatcgcttc ggccgtgttg tcgcccgcga tcggaggtgc cacggccgcg gacgcagcaa
  1079401 ggccgcatgt gtcgcttgct ccgcacgtcg cccgttattg gctcagaaga tccgtactgt
  1079461 tcatctgcac catcgcgatc ctatgggcta tcctcgatat gatgcgggcg cttgccttcc
  1079521 ccgcagacgt ccgcgaactc acctccgcgg tcctggggct tattgttctt ggactggctg
  1079581 tcgatacggc atggcggcga ccggtttccg aaatggcccc cgcgcgcagc gttctgcgca
  1079641 acgcctcgat cgtcggtttc ctgatcttgc tctggttttt ctggatcgcg ggcatggagg
  1079701 tgttgttctg gcttggcgtc tatgtcctcg ggctgccgcc attgctgcgc ttcgtcagcg
  1079761 ccgcgacacg gacaatgttg gatgctgccg ccgcggagga cttccgtgtg ctgcgcaatg
  1079821 ttttgattga acggggggcg aggctcgtca tcatagctct cgccgccgtg tggctagcca
  1079881 tgaccttccg cataagcggc gcgcagatga tgcaggacga cgccttcaat cgcattttcc
  1079941 gcggcgtgct ggcgggtata gtgatactgc ttgcggccga tctcatttgg cagttggcca
  1080001 aggaatccat caacgtgcgc atcgcgcgcg ccagcctgac ggtggaggat ccgggcgagc
  1080061 tcgcgcgcaa cacgcgcctg cgcacgctgc tgccgatttt gcgcaatttc ctcgcggcct
  1080121 tcatcgcagt cgttgccggc atgatggtgc tgtcgggtct cggcgtcgag gtcggtccac
  1080181 tgatcgccgg cgctggcgtt ttcggggttg ccatcggctt cggttcccaa acgctcgtca
  1080241 aggacgtgat cagcggcatc ttctacatga tggacgatgc ctttcgtgta ggcgaatata
  1080301 tccagagcgg cagctacaaa gggacggtgg aatccttcag tatccgttcg gtcaaattgc
  1080361 ggcatcaccg ggggccggtg tttaccgtgc cctttggctc gctcggcgcg gtgcagaaca
  1080421 tgagtcgcga ctgggtcatc gacaagttcc tgatcaatgt ttcctacgat gcggacgttg
  1080481 ccaaggtgaa gaaggtggtg aaaggggtcg gggccacatt gctcgaggac cccgagctgg
  1080541 cgccgatgat catcgaaaca gtaaagatga agggtgtcga gcaattcggc gattacggca
  1080601 tatccctgag cttcgcgatg aagaccaagc cgggacacca gacgcaagtc cgccgtcgtg
  1080661 cgcaggcgat gatcaaggac gccttcaaga acaatggcat ccagttcgcc tcgccgactg
  1080721 ttcaggtcgc cggcgacgac gcgcaatccg ggtctgcggc ggcggccgcg acgcgtgatg
  1080781 cgatcgccaa aaagaatgcg gccctggctc agggtgggga ggaagcggcg gaatagcggc
  1080841 cgcggtgatc gctgtaatcc tccacgcctg cgaagctgga tgtggcaggc ttctgttgac
  1080901 atcgggacgg gctgcgggat agctcgcccg aatgaagatc gcctttcacg cgccgctgaa
  1080961 atcgcctgat catcctgtcc cttccggcga caggcagatg gcgcgcatgc tgatcgaagc
  1081021 gctccggctg gccgggcacg atgtcggcgt cgtctctcag ttgcgcagct tcttgcgtga
  1081081 aacctcgcac tcggcatttt cagccgtgcg cgacgaatcc caacgggaaa tcgaccggat
  1081141 taggcgtctt tggcggtcgg aaggtccgcc cgacatgtgg ttttgctacc acccttacta
  1081201 taaggctccg gatctcatcg gtccttcact ctcgacggag ttctcgattc cctacgtgac
  1081261 cgctgagagt tcctattcgt atcggcgcaa catcggcgcc tggaagcttg cacaggatga
  1081321 ggttgccgcg ggtgcacggc gggccgcggt caacgtctgt ttcacccagc gcgatcggca
  1081381 cggcctcgat gaggcgatac ccggagcgcg cacggcgctg ctcgcccctt tcatcgatgt
  1081441 gtcgccgttt cgggacctgc gaaggacgaa acaaggcgag acccgtctgc ttgcggttgc
  1081501 gatgatgcga gccggcgaca agatggatag cttccgcatg cttgcccgct ccctcgctct
  1081561 cgtggcggac ctgccttgga agctgacggt cataggcgac ggtcccgccc gcgccgaggt
  1081621 gttggagacc ttcgcggcct ttccctcaga gcggctggag tggctgggcg aaaaagcgcc
  1081681 gcaggcggtt cccgcgcttc ttgccgccgg cgatctttat atttggccgg gctgcggaga
  1081741 ggcctacgga ttggcctatc tggaggcgca ggctgcaggc ctcccggtcg ttgcgcaacg
  1081801 cacggccggt gtgcctgagg tcgtcagaga cggcgaaacg ggatgtctga cgacgcccgg
  1081861 caacaccgag gccttcgccg cggcggttcg gcaattgctg gtggacgaag cctcgcgcaa
  1081921 gcagatggcc gagcgcgcgc ggcaattcgt tttcgagcag cgctcgcttc ccgccgccgc
  1081981 cgcgcgtctc tccggcatat tcgccgagtt tgtggattgt gcgaaatgaa gatgggatcc
  1082041 gcctggcaaa ggtgcgtgga caggctcgac gcgctgcagg atggaggcaa atgtatcgac
  1082101 ttctggctgc gggacgacga tgccgtggaa ccgtctcccg cccttgaccg gttgctcgat
  1082161 ctcaccggcc gcttctcggt acctgtgacc ctggccgtca taccggcaag caccgacgag
  1082221 cgcctttcgc gatctctctc cagtcgcatg catgtcgatg tcgccgtcca cggatggtcg
  1082281 catcgaaacc atgccccagc cattgaaaaa cggcaggagc tcggtgctca cagaccgcgg
  1082341 gagaccgttg ctgccgacct gcgcgccgga tgggctcgtc tgtccgcgct ttatccggct
  1082401 gctctggcgc ctctgcttgt tccgccctgg aaccggatcg atcctgggct ggtctctgaa
  1082461 ttgcaagaaa tcggtttcga ggcgctttcg gttttcggac cggaggacgg cgagaagtgc
  1082521 gccgcgttcc gggataccgg gctacagctc ataaataccc atgtggacgt gatggactgg
  1082581 cacggcaccc gcggctgtcg tccgcatggc gatatcctcc gcgacatcga tcgccggctg
  1082641 gatgaagtcg aaaacagcgg cgggtcggtg ggtattctca cccatcatct cgttcacgac
  1082701 gagagcgtgt gggagttcct ttcaaagctt ttcgagatca ccacctcgaa cccggcctgc
  1082761 cgctggcgca ggatcactga gcttatagat cgatgacctg gcggtcgcac gcagcgaagg
  1082821 cgccggggaa gaaagcctga acttcctgct ccatggcagc gagtgccgcg tcggtgcgcg
  1082881 acgggtcatg gtggaacatg gcgaggcggg cgacgccggc agccttcgca agcaatgatc
  1082941 cgtgcattcc cgtcgagtgt ccgtagccgc gaaaggcaga catttcgctc tccagatagg
  1083001 tgcagtcata gatcatgaga tcggctccgg cgatgaaatc gaggagtacg gggtcgagga
  1083061 tgccgggttc gtgttcggtg tcgtagatga gtgcgaccgc acgtccaccc cattcgacac
  1083121 ggtaaccgat gcatccgccg ggatgcacga ggctcatggt gcggatggaa acgtcctttc
  1083181 gcggggacag cgtttcaccc gggcggaaat cgacggtgtc gaggctcgcc tggcagatgc
  1083241 ccgttccaac ggggaaccat ggcggtctca tgaactcgtt gatcatctcc gccgtggtca
  1083301 tcttgccatg gaggtggcca gaccagaagc ggacagcgga actgcagcga tagatcggct
  1083361 tgaaataagg caggccgatg atgtgatcgt aatgggtgtg ggtgaagaag acgtcgaagg
  1083421 cggacacgcc ttcggacatg agcgacagcc cggcttcgcg caagcctgat cccgcatcga
  1083481 agatcatcac ctctttgccg cagcggattt cgatgcaggg cgtgtttcct ccgtagtgaa
  1083541 ggaactgctc gccggatacc ggcaagctgc ctctaacgcc ccaaaatttc actcgaaaag
  1083601 tatcgtcctg cattccgttc cggctttatc ctgccctgcc gtagcacatt gcccgggcct
  1083661 ggtgattaga caagcacaaa tcataagggt cctgcaatgc cattggctgt gtcacgcacg
  1083721 gtttgcatgg ttcaaagaga aaactattct ttgtcacgaa ggtgctttat ccatcagacg
  1083781 gggtgaatta tctggtgaat ttcgagcctt gaaacgacga caaacgtcag cttcgggagt
  1083841 ttggctacat ggtgcagccg gccgacaggg aattttacgc gaaccttccg cttttcgagg
  1083901 cattcgaagg tgtcgcagac gaggccaatt accggcccct gcccgaaggc tggtggcttg
  1083961 ccgttgccga catcgtggat tcgacgggag ccatcgcgga agggcgatac aagagcgtga
  1084021 acatggccgg cgcgagcgtc atctccgcgc tcatgaatgc gcttgacgag aaaaatctcg
  1084081 ccttcgtttt cggtggcgac ggtgcgctcg ccgtcgtgcc cggcgggctg gcggcaaagg
  1084141 caaaacacgc gctcgctgcg gcgaaaacat gggttgcgga agagcttgga ctggagcttc
  1084201 gcgctgcgat cgtcccggtc tcggacgtgc gcgccaatgg cttcgacatg cgcgttgcgc
  1084261 gcttcaaggc gagcgaggtg gtctcctatg ccatgttctc cggcggcggc gccagctggg
  1084321 cggaagcgga aatgaaggca ggccgttatc agattgcggc cgccccgacc ggcacacggc
  1084381 ccgacctgac cgggttgtcc tgccggtgga acccgatcgt ctcacatcac ggggcgatcg
  1084441 tatccatcat cgcagtgccg ggagagcgcg gcatcggacc tgaattccag gctttgatcg
  1084501 gcgacatcgt ggaactggcc gaaggggagg agcggggtgg gcaccccgta ccggaaaacg
  1084561 gtcccgagcc gcatctgtcg gtgcgcggca tcacggtgga atcgcgcgcc gtcgcgccga
  1084621 gaggccgccg ctccctggct tggttcttcg tcgccgcgca gagccttgct ctctttctct
  1084681 gcttcaggct cggcatcaat ttcggcccct tcgacgtcaa gcgatatgcg cgcgaccttg
  1084741 ccagcaattc ggacttccgc aagtttgatg acgctctgaa gatgacgatc gacgtcagtc
  1084801 tcgatcggct gcgcagaatc gaggagcggc tgaagcaagg ggtcgcggcg ggcatatgcc
  1084861 gctacggact gcaccggcag gatgcggcac tgatgacgtg catcgtaccg acgccgatga
  1084921 gccgcgacca catgcacttc atcgacgggg cggccggcgg gtacgcggtg gccgcccgga
  1084981 acctgaaggc cacccttgcc ggcagcgttt cacaggcggg aagtctacct tcgatgatta
  1085041 agccttgacg atgtgtccgg cggcaaggcc tcgacgtgca aagacattgc gcgtatctac
  1085101 gatcagcggc gaccagccgg caagcccggt atagtcgacg gtgtcatgat cggtcgcaat
  1085161 cagaacagcg tcgaagctgc gtaccgtcgc ttcgtcaaag acgaccgaac gtcggccctt
  1085221 caaggccata tattcgcgcg tggcgggaat ctcttccaca tgcgggtcat agaaggcggc
  1085281 cttcccgccg cgctcctcga tgagttctat cagcttgagg gaggggcttt cgcgaatgtc
  1085341 cggcacgttc ttcttgtagg cgagcccgac gacgaggacg ctcgagcggc tgagcgcctt
  1085401 gccctctcgc ttgtcgagcg cctctgccag cctggcgacg acatggcgag gcattgccga
  1085461 attgatttca cccgcgagtt ctatgaagcg cgtaggcagc tcgtattccc tggacttcca
  1085521 ggtcagataa aaggggtcga tgggaatgca atggccgcca agcccgggcc ctggatagaa
  1085581 gggcatatag ccgaacggct tcgtcttcgc cgcttcgatg acctcccaga tgtcgatgcc
  1085641 catcgcgtcg tagacgatct tgagttcgtt gacgagcgcg atattgacgg cccggaagat
  1085701 gttctcggtc agcttcacgg cctccgccgt ggcgtttgac gagaccggaa ccaccgtcgt
  1085761 gaccacggcg gcgtagaacc gttccatcag cgctgcggcc agcggtccgt ctcccgccac
  1085821 gaccttgggg atgctcgtcg tcttgaacga gcggttaccc gggtcttccc gctcgggcga
  1085881 gaagccgatg aaaaaatccg cgcctgattt gagccctgtt tcctccagga tcaagcgaac
  1085941 gatgccgtcg gtggtaccgg gataggtggt ggactccagc acgacgagct gacccggccg
  1086001 caggctcgcc gcgatcgagc gcgaggtgtt ttcgacgaag gagaggtcgg ggtcgcggtg
  1086061 cctggtaagc ggcgtcggca cgcagatgat gatcacatcg caaaggccga ggtcagaaaa
  1086121 atcggtcgtg gagcggaatc gtccagcctc ggattcgcgg gcaagcgcct cgtcctcgac
  1086181 cgcctcgata tacgaacggc cggcatccag cgcgacgatc ttgccaggat cgacgtcgaa
  1086241 accggtgacc tgaaagccgg agcgtgcagt tgctacggcg agcggcaggc cgacatagcc
  1086301 gagcccaatt acgccgacgc gggcggtgcg gcgagagatc gattcgagca gcctgtcatg
  1086361 gtgcggggat gtcaagattg gcttccagtt ctgttgccgg tggtgcggtt ccggcggtcc
  1086421 ggccgcgggg accattaccg tttgttggcg ggaaagacat cgcaagtcaa gcgccgctcg
  1086481 tttgccggca aagccgcgcg cttccttccc cgcgtcgtct tatctcgtcg ggcgaccaca
  1086541 cggtcgtgag agaccccggc agttttgagg gtgcaatgcc cagggcggtt gcgtgtacga
  1086601 tccgatgaca atcaaaaatc gctcgtggtc actggaaatt gcactcggcc gtgaatatct
  1086661 gcaggagcgc agcggtgacc cgatcgctgt atgacgaccg cgggaggtgg cgggagcttt
  1086721 ctttcaccga cgggtgccgg attcggtttt ttgccgcgag cgagcgatcg ctgcctcgcg
  1086781 gcctgcgccg atggcaaccg ttgccgcgac gatgaggatt atggcatgag cccgaacaac
  1086841 gacaacgttt ccgaaatcct cctggacaag gtcgctgact ggctcatgcg aacttcgctc
  1086901 agtgacgaga cactggaaac cattgtgcgt ggtttctgcg agcgactggc ggcggctggc
  1086961 ctgccgctca tgcgtgtcca tctgtccttt tccatgctcc acccgcttta tgacgccctt
  1087021 ggctttacgt ggtggcgggg tcgaggtgtc gaggtgagcg gccttcgtca cgaggaattg
  1087081 gcgctcaacc ccgagcggtt cctccacagc ccgtattatt atctgctcag caacaatctc
  1087141 gaccatgtca ggcgccgaat cgatccggcc ctaccgtcgg agttccccat tttcgacgag
  1087201 ctgaaggagc agggagcgac cgactacatt gccttcatgc aaccgctcgg ggccgaatcc
  1087261 gaacatggca tggtcggctc gtggacgacg gaccgccagg gcggtttcag cgacgacgtc
  1087321 atcgcggccc tgctgaggct tcagaaccat ctggcgatcg ccgccaaggt cgccgtgctc
  1087381 ggcaaactcg ccgacaacat gctgaccacc tatcttggcg ccaatgcagg gcgccgcgtg
  1087441 atgagtggcc aggtccggcg cggcgatgga gaaacggtac gcgcggttct ggtcatggcg
  1087501 gatatgcgtc agtcgacgat gctcgcggaa aaagagggaa ggcaggctta tatcgagtcg
  1087561 ttgaacggct tcttcgacgc gatcgccacc cccttcaatc gcaacggcgg acagattctg
  1087621 agcttcgtcg gagacggttt catcggcgtc tatccctgtg gccggcacaa ggagccctcc
  1087681 gagatggcca gccgggaagc cttcgccgcc gtgggggcgg caaccgctcg catggcggcg
  1087741 ctcaacgcgg agcgcaagac gcaaggccgt gatgcgatcg gctacggcat tgcgctccat
  1087801 gtcggtaatg tcatgttcgg caatgtgggc ctgcgcgacc ggctgacatt ctcggttttc
  1087861 ggctctgccg tcaacgaagt gcagcgcctg caaagcctga cgaagaaata cgaccacagc
  1087921 gtcgtcgcga gcgaagcctt cgtgaactat tgcggcgggg aatggcaaac gctggggcag
  1087981 gaaaaattaa ggggcgttcg ccagaagttc acggttctct atccgcggga taccgccctc
  1088041 gccgcaatcg cacaggagcg ggcatacgat gcaaccgagg atggactttc cgaggcggaa
  1088101 catgtcatgt tgctctaccg caacaagaag cggctgcctg cgccgcgcgg tctgatcgac
  1088161 aagatgcttc aatgagggga tcgatgtttc gtatagctct gcttgcggcg gcacttgccg
  1088221 tgccgggttt cacctacgct caatccgcgg acgagacgcc agcctatgaa cagaagttgt
  1088281 tcgacggttt cgagggcagg gattttgcgc ctgaaggcgg gctctactac cgcgataatt
  1088341 ttgagcaaag cgcgggctct tatgaattcc agagcgccgt caagcgcacg ggcgcggggg
  1088401 gcttgaagct tagcatcgtg ccccaatgcc ccaccgatca cgacggctgc agcgagcgtg
  1088461 cggagatctg ggaaaagacg gagctgcgcg tcccctacga caagggggtc tggtacggtt
  1088521 tctcggtgaa gctcgccgat ccggttccga gcgacgatca ccgctacctc atcgcgcaat
  1088581 ggaagcgtga aatcgatccc ggcgccgatg gcgacttcag ccccttcctg gcgttgcgca
  1088641 tggatttggg taagctcttc gcaacgatcg aaaccaacta tctgccgccg gtttcggccg
  1088701 gtccggcgaa cgtgccggca cgctgcggcg cgggcgaggt gccggtctgg ggccgccccg
  1088761 agctcaacca gatgcgtatg ctggtggcga ccgacggcaa ctggaagccg gaagacggca
  1088821 gcctcttcaa tgcatgcacg aacggggtca ccatcaccaa tcatggcaat cccttgccgg
  1088881 atccgaagtc cggctggatc gatttcgtcg tctttaccaa gcctggcccc gacggatcgg
  1088941 gccatataga actctttgcc aacggccagc cgatcatcac ggtcaagggc catatcggcc
  1089001 acgcggacaa ggggctcggc gagaaccagt acttcaagtt cggaccctat cgcgcggctc
  1089061 acacgatcga ctggaccgtt tattacgacg acttccggcg ctcgctccgt tgcgaggacg
  1089121 tcctgacgaa cggcaactgc ccgttctctt gatacgtacc gcccaacctg gcagcagttt
  1089181 cgggtgaaat gtacattcgg cctgctgcgc gttgcggtga gttcgaccga acacaatgca
  1089241 tttcaggccg ccatttggcg cttcgcgaac ctttccggcg gcgtgctgga cagcccgttt
  1089301 aacctacgct actgtttttg agtggtaata ggctacagcg ctatgcgtcc ggcggggcga
  1089361 gcacatgtcg ctgtaagccg ccgcatgttt cttttgatcg actgcgatca aggggccagg
  1089421 aaatatgggg caatcagggg ctaatgtgac ctcgcgcttt taagacgcgc ggcgctttgg
  1089481 gaagtggctg catgatttta ttctgggggc ggccccaatt gggatcgtgc aggaggggta
  1089541 tcgagggaag cgtgctgcga tgacgtcagg agcggacctg ctgcgagttg agggtctgcg
  1089601 gatcacattc tcagtgctgg gcggcggggt cgaagccgtc cgcggagcga gtttcagaat
  1089661 tctgcccgga cgggtgaccg cgctcgtcgg tgaatccggg tccggcaagt cggcgatcag
  1089721 ccaggcgatc atgggcatcc tgccgagcgt agcaagcgtc acgggccggg tggtgttcaa
  1089781 cgatccgacc gggaacaagc ccgtcgacct tctttcgctg gacagcggcg ggcgcgaaat
  1089841 ccaagatatc cgcggcgcgc gcatcagcaa aatctttcag gagccgatga catctctgtc
  1089901 gccgctccac acgatcggta accagatttc cgaagtgctg aagattcata cggatatcga
  1089961 caaggctggc cgccgggagc ggacggagca actgctcggc tatgtcggct tctccgaccc
  1090021 gaagcgggca tatgacatgt acccgttcga actctcaggc ggcatgcgtc agcgcgcgat
  1090081 gattgccatg gcgctgatct gcagtccggc gctgctcatc gcggatgaac cgacaactgc
  1090141 gctcgatgtt acggttcagg cgcagatatt acagctcctg cgcgggcttc aaagcaagct
  1090201 caacatggcc atgcttttga tcacccacga tcttggtgtc gtagccaaca tggccgacga
  1090261 ggtggtcgtt atctatcatg gcgagatcgt cgaagcaggg cccgtggatg caatcttccg
  1090321 caatccccag catccttatc tcaagggttt aatggcggcc gtgccgcact tcgacatgaa
  1090381 acccggcgaa cggctcaaag ctctgcgcga ggtgccggtc caggccggcg ggattatcgg
  1090441 cgatcgcgat gtcaggaaag ccggagggcc aaatgtgctc gtgtccgtcc gcaacctgtc
  1090501 gaagacgttc tccacgcgca gttcaggctg gttcggcagc ggctccgctt ttcggcaccg
  1090561 tgcagtggac aatgtcagct tcgacattcg ccgcggtgaa tgccttgggc ttgtcggtga
  1090621 aagcggatgt ggcaagacca ctataagcaa aatcctgatg cgagccgtaa cgccggataa
  1090681 gggaacgatc acgttcgacg atggtgaggg cgcgctcgac gtcctgaagc tcgatggcgc
  1090741 ggaactcaag gcgctgcgcg cgaagatcca gatggtcttc caggaccctg tttcttcgct
  1090801 gtcgccgcgc atgacggtca agaatattct cagcgagccg ctggaaatcc atggccgcgg
  1090861 aacgccgaaa tcgcgcgtcg aaaccgttcg ctcgctcctg caggcggtag gcctcgacca
  1090921 acgcttcatc aatcgttatc cccacagctt ctccggcggc caaagacagc gaatcggcat
  1090981 cgcccgggca ctggcgctcg tgccgcagct gctgatctgc gacgaacccg tttccgcgct
  1091041 cgatgtttcg gtacaggccc agatcctcaa tcttctcaag gatctgcaaa aagaactcgg
  1091101 ccttacgatg ctgttcatct cgcacaatct cgcggtcgtc gactacatgg ccgaccggat
  1091161 cgccgtcatg tatgcgggcc ggatcgtgga gctggcaccg cgtgaagtcc tgatgagcga
  1091221 cccgatccac ccctatacca aatcgctcct cgctgccgtt ccctatcctg atctcgatcg
  1091281 gaagctcgat tttgatttgc ttcaggtgag cggcgggtcg gaccagcagc gctggggcgt
  1091341 gcagttcgcc gatggtggcg atgacgaggc tcttgttccc gccgatctcg gcggcggcca
  1091401 ttttgtcctt gcccgcaaat cggtggatgc cagggagtta cgcccatgat cacccgcaga
  1091461 accgcgctcg gccttctcgc aacggcggcc tttcctaaaa ccttgcttgc ggctgcaggc
  1091521 ggggccgacc cgctcgctgc cctcgttcag gagggcaaac ttcccccggt cggcgaaagg
  1091581 ctgccgaaga cgccgcgggt gatcaatgtc gcggggatgg gccgcaaagc cgggcggcac
  1091641 ggcggcacca tccgcagcct gatcggcagt gcgaaggaca ttcgcctgat gacgatctat
  1091701 ggctatgcac gcctggtcgg gtacgacgag gaactgaacc tacagcctga cgttctcgaa
  1091761 agctacgaaa cggtcgagga ccggattttc accttccacc tgcgcgaggg ccataggtgg
  1091821 tccgatggca cgccgctgac cgccgaggac ttccgttact gcttcgaaga cgttctgctc
  1091881 aacgaggacc tttccccggc aggcctgccg acctcgatgg tgatggatgg tcaagcgccc
  1091941 aagctcgaaa tcgtcgacga acggacggtc cgctattcct ggccgatgcc aaatccggtc
  1092001 ttcctgcagg aactcgccgc gccgcagccg ctgatcgtgg cgatgccttc ggcctatctc
  1092061 aagcagttcc acaaaaaata tcaggaagag gacaagctga agaccttact gaaagaacag
  1092121 cgggtcaaga ggtggagcca gctccacatg cgcatggcac ggtcctaccg gccggagaac
  1092181 ccggacctgc ccaccctcga cccctggcgc aacacgacgc cgttgcctgc cgaacagttc
  1092241 gtcttcgagc gcaatcccta ttaccaccgg gtggacgaaa acggcctgca gctgccttac
  1092301 atcgaccggt tcgttctcag cgtgagctcg tccgcgctta tcccggcaaa gaccggcacg
  1092361 ggcgagagcg acctgcaggc aaatgggatc gatttcgtcg actataccta tcttaaggat
  1092421 gcggagaagc ggtatccggt cgaggtgaag ctctggaaga agacctcggg atcgcgcctg
  1092481 gcattgctgc cgaacctcaa ctgtgccgac ccggtgtggc gggcgttgct aagagacgtg
  1092541 cgcgtccgtc gggctctgtc gctcgcaatc gaccggcgcg agatcaacat ggccgccttc
  1092601 tacgggctga cgaaggagag cgccgatact gtgctgccgg aaagccctct cttccgtccc
  1092661 gaattcgcaa gtgcctggat cgcacatgac ccggagcagg cgaacaccct gctcgacgcc
  1092721 gcagggctgg ccaaacgcgg cagcgacggg atccgtattc ttcccgacgg ccggaaggcg
  1092781 cagatcgtcg tcgagacggc cggcgagagc acactcgata cggacgtgct gcagctgatc
  1092841 accgactatt ggcgtgaagt cggcatttcg ctcttcatcc gtacctctca gcgcgatacc
  1092901 ttccgcagcc gtgcggtggg gggcgagatc atcatgtcga tatggttcgg tatcgacaac
  1092961 ggcgtgccga cggctgacat gagtcctcac cagctcgcgc cgacagcgga cgaccagctg
  1093021 caatggcccg tctggggctt gaactatatc tcccacggcg aaatgggaga aacgccagac
  1093081 cttccggccg tggtcgaact tctggagctg ctgaagcgct ggaggcattc ggccgacgat
  1093141 gcggagcggg cggacatctg gagaaagatg ctgtccatct atacggacca ggtcttctcg
  1093201 atcgggctgg tcaacagttc cctgcagcct atcctcgtga ccaagaagct gcgcaatttc
  1093261 ccggaagagg gcctttgggg tttcgacccg acgagctatt tcggcgccta caagcccgac
  1093321 accttctggc tggaacagga cggctgagat gctgcgatac atattatggc gcatcgcggt
  1093381 tatggtcccg acgctcctca ttatttccgc gtttgtcttc gccatcatcg agctgccgcc
  1093441 gggcgattat ttcgagagct acatcgccga gatcagggcg cagggcgaag gcgtcaacat
  1093501 ggagcagatc gaggcgctgc ggaagcaata tggcttcgac cagccgccgc tcctgcgtta
  1093561 cgttcactgg gtggcgggaa tgctccaggg cgatttcggt tactccttcg agtacgaact
  1093621 gcctgtgagt gacgtcgtcg gcgaccgcct gtggctcacg gtcctcgtct ccttcgtcac
  1093681 catcatcttc acctgggtca tcgccttccc gatcggcctc tatgccgcca cgcaccaata
  1093741 tagctggggc gattacggcc tgtcgctcgt cgggctcatc ggcatcgcga tccctaattt
  1093801 catgctggcc ctggtcctca tgtatttcgc caatatctgg ttcgggactt cgatcggcca
  1093861 cctgatggac cagaaatatc tttccgaacc gatgagctgg gcgaaggcga agtcgatcct
  1093921 ggagcatatc tggattccgg tcatcatcgt cggcgcggcc ggcaccgccg gcatgatccg
  1093981 gcgcttgcgt gccaatcttc tcgatgagct tcagaagcaa tatgtcgtta ccgcccgcgc
  1094041 caaggggctt tcaccgacgc ggaccctgtt gaaatatccg ctgcgcatgg cgctcaattt
  1094101 cttcatttcc gatatcggct cgatcctgcc ggcaatcatc tcgggtgcgg agatcacggc
  1094161 catcgtgctg tcgctcgaaa cgaccggacc aatgctgatt aaggcgctgc agagccagga
  1094221 catgtatctt gccgggtcgt tcctgatgtt cctcgctttc ctcacagtga tcggcgtgtt
  1094281 ggtttccgat ctggcgcttg ccgtcctcga tccccgaatc cgtctccaag gcaggagcac
  1094341 aaagtgacgt caccgatccc ggcgcccggc gagccccttc cgcattacgt ttcgactgcg
  1094401 cccttcgatc cctattccgt cgaggtgatg accgaagagc aggtgcgggt aaatcaggca
  1094461 tcgcagttgc gcctgatgtg gtggaaattc aagcgccaca agattgcgct cgcttccggc
  1094521 attttcctgg cagcgcttta tggaatgatc ctgatctgcg agttcctggc gccctacgat
  1094581 ctgcacacac gcaatgtcga cttcatctat gcgccgccgc agagcgtcca cttctttcac
  1094641 gagggcgaat tcgtcggccc cttcgtctac gggcggacga tgaagctgga catggatacg
  1094701 ctgaagcgca actacaccga cgatatgtcg gatgtcgagc cgatccggtt cttctgccgc
  1094761 ggtgacggct atcgattctg ggggctgttc gaaagcaatc tgcatctggt ctgcccggcc
  1094821 gaaggagggc agcttttcct tctgggtacg gaccggcttg gccgcgacgt gctgtcccgc
  1094881 attatctacg gcgcgcggat ctcgttgacg atcgggcttc tcggcatcac cgtcagcttc
  1094941 gttctcggta ttgtgatcgg cgggcttgcc ggatatcacg gcggcgtctt cgacctcctg
  1095001 gttcaaagat tgatcgaggt cctccagtcg atccccagca tcccgctctg gctttcgctg
  1095061 gcggccatca tgccggcgac ctggagcccg ctcctcattt atctgggcat aaccgtcatc
  1095121 ctcggccttc tcgactggac cggccttgca cgcgccgtgc gctcgaagct gcttgcgctc
  1095181 agggaggagg attacgtcct tgccgcgcaa ttgatgggcg cgaaaagcgg ccgcatcatc
  1095241 gggcgccatc tcgttccggg cttcatgtcc catctcatcg cgactgcaac gatctcgata
  1095301 cccggaatga tcctcggcga aacggcactg agcttccttg gactcggcct gcgtcctccg
  1095361 ataaccagct ggggcattct gctcacggaa gcaaagagcg tcagcgtcat cgccttttat
  1095421 ccgtggctgc ttttccccac catcccggtc attcttgtga tattggcgtt caacttcctg
  1095481 ggagacgggt tgcgtgacgc cgccgatccc tacaaataac gccggtatcg ctgttggccg
  1095541 caagcgatcg ctacaataga cttcgacgtt tctatctttg agcgaaaggc ttttcgtatg
  1095601 acacggcgct tcgaggatgc ccgcatcctc atgtacagcc acgatacctt cggactcggc
  1095661 catctcagac gttgccgcgc aatcgcccat gccctggtgg aagactatag cggactgcag
  1095721 gtcctcataa tctccggtgc gaccatcgcc ggcgccttcg attaccgcgc gcgcgtcgac
  1095781 ttcgtgaaga tccctagcgt tataaagctt agaaatggcg aatatacctc gctcgaccgc
  1095841 catatcgaat tgcacgaaac gctgaagatg cggcagtcga tcatccgctc gaccgcggag
  1095901 acctttcggc cggatatttt catcgtcgat aaggagccga tggggctgcg cggcgaggtc
  1095961 gaagacacgc tcgcctatct gaagacccac ggcaccaggc tcgttctggg cctgcgtgaa
  1096021 attatggatg cgccgcacct actcgaagag gaatggaacc ggcgcgatac gatgcgaaaa
  1096081 atcgagaagt tttacgattc ggtctgggtg tacggcccgc cggactttta cgacccgctg
  1096141 gtcgggctcg aagtgccctc agcggtgcgc gaccgcatga actttgtcgg cttcctgcag
  1096201 agaagcgtcc cccaggacgc cgtgcccggc cataaaccgg aaggcgacta cattctggtc
  1096261 acgaccggcg gcggcggcga cggagcggac ctcatccacg acgtgatcca cgcctatcag
  1096321 gaagatcccg aactcaagca taacgccctc gtcgtcctcg gcccctatat gccggcaaag
  1096381 cagcgcaaca agctgatcaa gaagggaagc aagatccctt tcatcaagat catcgagttc
  1096441 gacaaccgta tggaggagtt gatcgccggc gccaggggtg tcgtatcgat gggcggctac
  1096501 aacacctatt gcgagatact gtccttcgac aagccggctc tgatcgtgcc gcgcctgcag
  1096561 cctcgcgaag aacagttgat ccgcgcccaa cgtgcctccg cgctcggcct catcgacatg
  1096621 ctgcttcctc aggaagcgga agaaccttta cgttttgccg cggcgctcaa ggcactgccg
  1096681 cagcgtccgc cgccatcgct ccgcgccaag ggtttgaggc tggaaggcct cgtgcacata
  1096741 tccgacatcg tcggcgaatg gctcgaccat cggtcgaaag agcatttggc cgtcgtgaaa
  1096801 agatcgaact gaagacacgt gtccctgaaa ccgaagatcg ccgtcgtgct gaagggttat
  1096861 ccgcgccttt cggaaacgtt catcgcacag gaattgctgg gccttgaaag agcagggcat
  1096921 gaactcgtcc taatcgccct gcgccgaccg actgatggga agcgccaccc cgtccatgat
  1096981 gaaattggag cgcccgtcca ttaccttccg gaatatctgc acgaggagcc gtggcgcgtc
  1097041 cttcgcgccc taacgaagac cgtgacgaaa cgctccttct ggcggatgct ccggccgttc
  1097101 ttcagggatc tcgcgcgcga cagatcgcgc aaccgtttcc gtcgcctcgg ccaggctctg
  1097161 gtgctcgtcg ccgaatggcc ggacgatgcc ggctggttgc atgctcattt catacatacg
  1097221 ccggcatcgg tgacaagcta tgccagcatg atctccggca taccctggac ttgttccgcg
  1097281 catgccaagg acatctggac ttcgcaggat tgggagcttt ccgacaagct cggccgcgcg
  1097341 cgctggacgg tgacctgcac gcgaagcggc tatgagcacc tgcgggacct gtcgagcgac
  1097401 aagacccgag tgcatctgag ttatcacggc ctcgatctcg atcggttccc gtccttcgaa
  1097461 ggtgagcatt cccggcgcga tggcagtgtt ccggacgacc cggtgcgcat cgtcagtgtc
  1097521 ggacgcgccg tctcgaaaaa gggatatgac cttctcttga aggcgctgtc gctgctgcct
  1097581 gcggacctca gctggcgctt cgatcatata ggtgcgggcg agctcaccgg caagctccag
  1097641 gcgcttgccg gtgaactcgg cctcgaagat cgcttaggat ggcacggcgc actggatcaa
  1097701 aaggaggttc tgagccgcta ccgagaggcc gacatcttcg cgctcgcctc tcgggtcgcg
  1097761 gcgaatggtg accgagacgg cctgccgaat gttctcgtag aggcatcgag tcagcgcctt
  1097821 gcctgtatct cgaccgcggt ctccggaata cccgaactta tcgatgacgg tcataatggt
  1097881 atgctggtgc cgccggaaaa tccgacggca cttgccgcgg caatagagcg attgatccgc
  1097941 gatccggatc ttcgccggca acttggtgcc gccgcggaac ggcgcgtgcg cgccgatttc
  1098001 gaccaccatt cgagcgtcgg tcagttgatc gggctcttcg aaagcgaatg gagaagaagc
  1098061 ccttgagcag cccccgcgtc cttttctatg tccagcacct tctcggtata gggcatctgg
  1098121 cgcgcgccag ccgtatagcc gaagccctca tcaggcggga tttcgacgtc acgatggtga
  1098181 cgggcggtac gccggtaccg ggcttcccgg gggatggcgt gaagaccatc gctctgccgc
  1098241 cggtgacggc aggcgacaag ggcttttcgg ggctcgtcga cggcgagggc cgcgcggtca
  1098301 cggcggcttt ccaggaacat cgccgggatc tgctgctcga gatctaccgc cgtgtggtgc
  1098361 ctgaagtcgt catcatagag gccttcccct tcgggcgccg gcagatgcgg ttcgagctgc
  1098421 tgccgctgct cgccgagatt gccgcgagtg accggccgcc gctcgtcgcg acgtcgctgc
  1098481 gcgacattct gcaggagagg ctcaaacccg ggagagccga ggaaaccgtc gaaatcgtca
  1098541 agaaccattt cgacctcgta ctcgtgcatg gcgatcccgg attcgcgcgc atcgaggaga
  1098601 cgtttcccct tgcgggcgaa atcagcggca aggtggtata caccggcctc gtagcgccgc
  1098661 cgcggccgac tggagtgccc gagaaatttg acgtcgttgt ttcggcgggt ggaggagccg
  1098721 tcggcagcgc gctgattggc gcggcacttg cggctgccaa gcttttgccg aacgcacttc
  1098781 gctggtgcct tgtgaccggc ccgaacctgc cgcaggcgga tttcgacgca ttcgcggctg
  1098841 cggcaccgcc gggcgtaagc ctctttcggt tccggcggga tttcgggggc ctgcttgccg
  1098901 gtgcccgcct ttccatctct caagcgggct acaacacagt gtgcgacatt ttgcgtgccg
  1098961 ggtgcgcttg cctgctcgtt ccctttaccg cgggcggcga aaccgaacag cgtatgcggg
  1099021 ccgcacggct tgaagagctg gaccttgccg gcgttctgcc ggaggagggg atcacgcccg
  1099081 agctgctggc cgcgaaggtc ggcgcgatgc ttgcccgccc gaaaccggcc atcccgccgc
  1099141 tggacctcga cggagccgcc ggaacggcga ggaccatcga agagcggctt ccgggcaggc
  1099201 ggtcttcaaa ggtttagagc acttctcccc atcaaatggc gagacgatct cggtagcggg
  1099261 aagcgccgtt cgcgccctgg tcagacagcc ccgatcagca tgaagcgcct gtattttttc
  1099321 atcggcagcg tccctgcgaa ttggacatgg gcaaggcgcg cctgcgcctg aaattcttcg
  1099381 agcgagttga cgcaactgat atgggtgggc tcgctaaaat agtcgttcga ttgcaggagg
  1099441 acgcgcgtgc cgggcggcag aaggtccagc cagctccgca ggtcggtgat gtgctcgcag
  1099501 ctcgtgttga tcagcaggtc ggcattcaga gcgcgatagt cgagcgcgtg catatccgcc
  1099561 gtcattgcaa cgaatctgtc gccgaaggct gcattgagcg tctgcgcgac aggctcgact
  1099621 gcggggtcga tgtcgcagct cacggcaatc tcgatgtcga agcgcggatc ttcgagcatc
  1099681 attgccggca gaatgccata ccagccgccg agcacgacga cccggcgaca ggacgcgccg
  1099741 atggtcgcga aaagcgtatc gcgggcccac atcttgcagc cgacctgctt gtgattgaag
  1099801 gcattggcga tttttgcttc cggatgcttt gcgatgaccc tcccaatgcc ggcaacgagc
  1099861 cggctgccgg aataggcggc cagcccccgg gcaaggtcat aggcgttttc gcgccaatct
  1099921 tcgggaaggt ggggggagtg gctggcatgc atcatgcggc tgttgtaagc tcacggtcag
  1099981 ttgagcgcaa ggcgctagca ccgtgggtga ggtagcggca tcaagcttgc tgccgcgccc
  1100041 ggattgctgg tctcggtctt tcaggataga tatgcgggaa ttcgaagttc tgcagcattt
  1100101 cttgtccgcc tgttgggacg cggtactgta gtctggtcgt tgggcatggg gtaccgtttc
  1100161 gctttcatgc cggccggtta cggtttcgtg gaggtgtcgc aagcctattg aagatcaggc
  1100221 ggaccagtac caagtgcggc gggagtccgc cggcgacata gccgtgcgat tccatatttc
  1100281 agataggtct ctttaccggc acatggaacc acttctttcc cgctacatct ggacacacac
  1100341 ccgcaagcag cagctctgga tcctgctggt cgtggcgctg tcgatggttc cctatttcct
  1100401 gtccttcgat ctgccgaagc agatcgtcaa cggaccgatt cagggcgcag gcttcgacgg
  1100461 tcccgaggcg acgcaacctt tcctggcgat ttccttcgat ctgccgttct tcggagaggt
  1100521 caatctcttt tcgggtttcg atctcggcag ggaagggatg ctgctggccc tcagcctggt
  1100581 gttcctgctg ctcgtcatca tcaacgggtt gtttaaattt tatatcaaca cctataaggg
  1100641 ccggctcggc gaacggcttc tgcggcgcat tcgctttgaa cttgtcgacc gcgtccttcg
  1100701 ctttccgccc ggctatctca agcgcgtgaa gccggccgaa atctcgacca tgatcaagga
  1100761 cgaggtggag ccgatgggcg gctttaccgg cgacgccttc gtacagccgg cgctgctcgg
  1100821 cgggcaggct ctgacggcgc tgatcttcat cctcctccaa agcttctggc taggcatcat
  1100881 cgccgccgtc atcgtcgcgg ttcaggcgat catcatcccg cgcatgcgcc ggcggcttct
  1100941 ggtcctgggc cgcgagcgcc agcttacggc ccgcgagctt tcgggccgcg tcagcgagat
  1101001 cgtcgacggc ataggcacga tccgcgccca cgacacgtcg aattatgaac gcgccgatat
  1101061 tgccgcgcgc ctcggccgca tattccagat ccgctacgac ctctatcaat ggaagtttct
  1101121 ggtcaaattt ctgaacaatt tcctggcgca ggtgacgccg ttcctcttct attcgatcgg
  1101181 cggctatttc gcgctgcagg gccggctcga catcggccag ctcgtcgcgg tcatcggagc
  1101241 ctacaaggac ctgccgggtc cgctcaagga attgatcgat tgggaccagg cgcgccagga
  1101301 cgtgcaggtc aaatatgcgc aagtcgtcga gcagttcagc gtcgaaccgc tgatcgatcc
  1101361 caaagtgcag gcgatctccg tcaatcccgc agcgccgctc accggtgcgc tggcggccgt
  1101421 caacctttcg gttgccgacg atggcggctc gaaagtggtg gagcatatat ccctgcagat
  1101481 ccaaccgggg gaagcggtcg cgatcaccgg cggcacgtct gggggcggcg aggcgctggc
  1101541 tgaggctttc ggccggctga cctggcccgc aaccggccgg atcgttattg gcgacgccga
  1101601 tattcacaat ttgcctgaag cggtcgtcgg ccggcgaatc tcctacgctt cctccgacgt
  1101661 ctttgccttc cagggcagcc tcggggacaa cctgctctat gggctgaagc acgccccgct
  1101721 gacggaggtg gcctatgagg gcgacaggga ggttcaccga aaatgggagc ttgtggaggc
  1101781 aaaactagca ggcaatccgc attacgacct gaacagcgac tggattgact accaggcggc
  1101841 gggtgcgacc gggccagacg accttttcac caagatcagg gccgtgctgg acgttgtcca
  1101901 gctgagtaac gacgtccttg ccctggctgt ccgttcgacg atcgatccga gcgagcacga
  1101961 agccttcgcc ggcgaaatcg tggcgatgcg cagtgcgctc cggcagcggc tcgaggctga
  1102021 gaagctcagt gacctcgtcg tgttcttcga acccggttcc tacaatgtcg aggcgaccgt
  1102081 gggagagaac ctgctctttg gcacggtcac tgacaataac cgctgggaga tggcacttga
  1102141 agaacatccc ttcttcaaga ccgtgctgaa gcgggccggc ctgcacgaga ccttctacgg
  1102201 gatggggctc gaaatcgctg aaaacgtcgt ggaactgttc cgtgacttgc cgcccgacca
  1102261 tcctttcttc cagcagctca ccttcatgac tgcggaggaa attccggcct atgaggcgct
  1102321 tctacagaag gtgaggggga aatctctcga ggaagtgtcg gaagacgatg ccatcaggat
  1102381 catccgcctt tgcttcggct atatcgagcc gcggcatcgt ttcggtctgc tgacggaaga
  1102441 tctcatgcag aagatcgtcg aagcgcggcg cgagttcagc gacggcctac cggccgatct
  1102501 cgtcggaatt atcgagcact atcagccgga ccgctacatg gcgtcggcca gcatcctgga
  1102561 caacgtgctc ttcggccgca tcggacacaa gcacaccgac gggtccgagc ggatacgcgc
  1102621 gatcgtgcgc gaccttttcg agtcgctcgg gcttcacaac aaggtgctcg tcttcgggct
  1102681 ggatttcgac gtcggtgccg gtggcaagcg cctgacgtcc ggccagcgcc agaagctaaa
  1102741 tctcgcacgc gccctgatcc gcgtttcgga cttctacatc ttcaatcagc cgctcctggc
  1102801 gctcgaccag cgcacgcagg accagatcac ccggaaggcc tttgcgttcc tgagagatgg
  1102861 cgagcgcaag cctgcgattt tatgggttct ggccaaccag gacctgacgg aactcttcga
  1102921 ccgcgtcgcg catttcgaaa acggacggtt ggtgcgcgac gaaccggtgg aaacgcgctc
  1102981 tacagacagc gactacaagg aactggcatc ttgatgtaat attgctgtca ggaggcaggc
  1103041 atattttccc gccggcatgg gttagagcct gtttgcacca accgcgacgc attcggagac
  1103101 acggactgtt atgctcctaa aagatgaagt ggaaatgctg cgccggataa cgctgttttc
  1103161 cggactaccg cctgcgaagc tcaagcttct ggcattcacc tccgaccggg tgatgtacag
  1103221 cgcgggagaa gatctgttca accaggggga tatcggcgac gcggcttatg tgatcctgtc
  1103281 gggcaatgcg gatgtgctcg tgtcgacgcc gaacggacag ctgaaagtcg ccgaagtgga
  1103341 gcagaattcg atcgtcggcg aaatcgccat tctgtgcaac acgccgcgca cggcaactgt
  1103401 caaaacgacc accgcgctcg aagcgctgcg catccggaaa gacgattttt tgaagctgct
  1103461 ggctgatttc ccggaaatgg cagtcgagat catgcgggtt ctggccgacc gactgagcca
  1103521 gacgacatcc gaattgacgg aagcccgcag tcgcgtgcaa agggccgagg cctgaacgtt
  1103581 tcaatcctct ctcatccccc actcaccgaa ccggacaccg ctgccgtctg gaattgctcg
  1103641 caagctcatt ccctccggcg ggaacggcgc tctcgttctt tttgtcgcat ttcgtcacgc
  1103701 gagcccgttt ccacttcgtt cggaaatgct ttagagaagc gcgatgcgag cgataactta
  1103761 tttcaaaaga acagtatatt ttcccgaaaa accggaaaaa gcgcgtttct ttcgccggct
  1103821 gcaggccggt cagtgggagc catgcacttt ccgcaatatc gcgcgcttcg tcgatgagag
  1103881 gacgacctat atcgatgtcg gcgggtggat cggagtgacg cccttttggg cggcacagac
  1103941 cgccaacaat gtcattgtcg tcgaaccgga cccggtttgt ttcggcattc tcaccgagat
  1104001 gaaaaatgga aacaccggag aggtcgcact cgtcaacgcg gcgctttcgc aggacgaatg
  1104061 cctcgttctg cattccgtgg gcggaggctt cggaagctcg gagacatcgg cgctcatagc
  1104121 cgacgatacc ggcatgtcga tagaggcaaa aacgatcaca atccccgagc ttcaggcgat
  1104181 ggcgaggacc gatcggctct gcttcaagat cgatatagaa ggttacgagt acaaggtgct
  1104241 cgaccagtta cgcgcgatag accgcaagaa gacggcgggc gtgctgctcg ccgtgcatcc
  1104301 ccagatcctg gccgcttcac tctcaggacc tgcggttctg cgcttgatca ggactgcggc
  1104361 cgcgaccttc cgcctcataa gaagcttgcg tggctttcga ttggagaacc cgtcggcgct
  1104421 ttggactgcg atccgcaaat ccgtctccaa aggcgaactg aggggctttg acctgctctt
  1104481 cgtcgcgcgt tgagaagacg cattgagtca aagcgcctcc gcaaaagcag ccggcagcct
  1104541 ggcatgaggg ctttaccgtc tgtcgcgaaa tggtcgatcg ggtatgcagc gcccgaacct
  1104601 gactaatctg gagccggtca accgaccgct tggacatcgg tttgtgcgaa gtcattcgct
  1104661 tatagaacag gggtaagccg gctcttcgcg ccagcgcata cgagagacag tcagcaaaat
  1104721 tcgaggcagc agggttccgg cctttgccga aggcaagcca ggcctgtgtg gcggtgtcca
  1104781 ccagttcgga gtcgatcggc acaatgtcga tgcggggctt tgtacagcca aagatcgagg
  1104841 tcgttgaccg accgctcatc gcgacgcgtg accaggacca ttctggcctc gaacaggcag
  1104901 gcggccggca acaggcggat cttgcaccgc gggccgttcc acatatgcgg gttggttttt
  1104961 caggctccga ataaaaagga ttcgacagat acgatcagct aatataccgc tgcttaatcg
  1105021 attaatcatc cgatgtggcg gaaaccaggc cttggcacgt tccggaccca aattgacgag
  1105081 gatagccaat acactcggcg tctccgcggc gaccgtctcc aacgcgcttt ccggcaaggg
  1105141 acgggtttcg gcggaactta ctgatagaat tcggtcgatc gctgccgacc tcggctacgt
  1105201 gccgagccag gcggggaggg cgctgaggac gggcaggagc ggcgtcatcg ggctggttct
  1105261 gccggatatc agcaatcctc tctttcccca gatcgcgcag gcgatcgagt ttgcggcttc
  1105321 ttcggcaggc tatggtgttt tgattgccga ttcgcgcggt gacatcgcca tccagacgag
  1105381 ggcgatcgaa cggctgatag aacgcggcgt ggacggtatg gtcatcgtac caaggcgcgg
  1105441 cacccgcatc gccgatgtcg gctgcccggt tgcggtcgtg gacaccccgt ccacgcctgg
  1105501 caatacggtg gccgcggacc attgggacgg cggaaggcag atagccgatc acctcgtagg
  1105561 cctcggccac agacatttgc tgatcatcgg caacaatcca gcctcgaacg tgcagaacga
  1105621 ccgtgtcggc gggcttcgct cggccctccg ggaagacgtg tgcgcggaga ccctatggat
  1105681 cgagcggctg gaagaggtga atggcaaggg ctgttcgctc ggccttgctg cgaaggtagc
  1105741 ggagggggta accgcctttg ccgcgatttc ggacctgcat gccctgcgcg cgctcacgga
  1105801 actgcagcgt gccggcatcc atgttccgga gcaggcaagc gtcaccggct tcgacgacct
  1105861 catctggtcg ccggtggtga cgcccgcctt gaccacgatc cgtatggaca tggcgcgcat
  1105921 tgccgcgatc gcggtcgagg ctctggttcg ggcgatcggt gccgaggagc cggaacaccc
  1105981 gtccgtagga gcgccggttt gcgcgccatt ctcgaaagtg cccatgcagc tcgtcgtccg
  1106041 gcaatccacc gcgacgccgc ccaccaccgc gacgccacca tttgtcactc aaggagaaca
  1106101 gccatgaaga acattatgct cgcctcgagc gcgctcctct tgatcggcac cacagccgca
  1106161 tccgctcagg aaaaaaccct caccatctcc gtctatggct ttgcccagga cgcgttcaag
  1106221 gagctggtct atgatccctt cgaagccaag tgcggctgca atctcgtggt cgaaaccggc
  1106281 aatagcgtcg aacggcttgc caagatggag gccaacaagg ctaatccggt cgtcgatatg
  1106341 gcggtcgttt ccatggccga tgcgctttcc gctacccggt ccggcctgat cgagaagatc
  1106401 gacacctcga agctcagcaa tttcgataag ctttacgaca tcgccaagga tccgaacggc
  1106461 gacgggatga gcgtcggcta taccttctac gccacttcga tcgtctaccg ctccgacaag
  1106521 gtggaaatca cctcctgggc cgatctgctc ggcgacaagc tcgccggtca tgtggctctc
  1106581 ccgaatgtta cgaccaatca ggggccgccg acgctttaca tgatcggcga agcgcttggc
  1106641 cagaacacgc cggacctcaa ggccgcaatc gccgctgtcg gcgagaagaa agacgatatc
  1106701 gttaccttct acgtgaaatc ctcgcaactc gttcagctga tgcagcagga ggaaatctgg
  1106761 gcggcaccga ttggacgctt ctcctgggag ggatttacca agatggacct gccgatcaag
  1106821 tgggcgaccc cgaaggaagg ccagaccggc ggcatgaacg tcatggttct ggccaagggt
  1106881 tcgaagaacc aggatctggc gttgcagttc atggatttct ggctctcgac tgagatccag
  1106941 acggcgctag ccgaaaagct ggtcgacagc ccggccaaca aggaggtgaa ggtttcgcct
  1107001 gaaatcgccg agaatcttac ctatggcgaa gaaacggtca ggaacctgaa gctcatccca
  1107061 tctgcggtgg cgctcgacaa tcgggaagcg tggctctccg agtggaacgc caaggtcggg
  1107121 cagtaagaag agctgctttc ttcgcgcgcg acgcctgacc aatgcggcgt cgcgttgcgc
  1107181 atccaacggc ggcagtgccg cggaaaggtc tagaaatgtt ccacaaccgg gccgaggcgc
  1107241 tggcgcttgc cttgccggcg gccgtattcg ccgccgtcgt ctttctggcg ccggttgtca
  1107301 tcctgcttgc cgaaggcttt cacaacgccg aaggctggtc cgttgccgcc tataccggct
  1107361 ttctgtccga tccgctcaac cggacggtat tcctgcgtac actgaggctc ggcgcaacgg
  1107421 tgaccgtggt cgcagccgtt atcggctatg ccgccgcctt cgccatcgtc aacctgccgc
  1107481 ccacagccaa ggggcggatg atcggccttg tcgtgctgcc gctgatgata tcgccggttg
  1107541 cccgcaccta tgcctggatc gtcatcctgg ggcggaccgg aatcgtcaat caggccttga
  1107601 cgagcgtcgg actgacggac gaacccatac gcttcctgtt cacggagacg gcagtcttcg
  1107661 tcgggcttct ccagcttttc ctgccgctga tgatcctggc gctgatcagc gcactcgaaa
  1107721 acatgccgaa ggatgccatt cccgctgcac gggtgctcgg cgccaattgg ttccaggtct
  1107781 tctggaaggt cattctgccg ctgacgaagg aaggtctggt catcggcggc acgctcgtct
  1107841 tcaccggctc cctgactgcc tacatcaccc cggcgattct tggaggctcc aaggtgctga
  1107901 tgctggagac gctgctattt caacgggtga ccgttgccaa cgatttcgta tccgcaagcg
  1107961 tcatcgcctt catcctgatc gtcatgagct tcgcagccaa ccttctcttg aagcggctcg
  1108021 cgaccgcgag gagcaaacga tgaattcccg tctcttcccg gtagtggtgc tttttctcgt
  1108081 caccgctttc ctgatcggcc ccttcttcat catcgtcgct gcatccgttt cgggaggcga
  1108141 gaccctggcc ttcccaccgc agggcctgtc actgaaatgg gtcgcgaagg tcttccaggt
  1108201 cgagagtttc cgcgagagct tcgcgatgtc gatgctgctc gccatcggcg gaacaggcgc
  1108261 cgctcttgtc ctcggcatcc cggcatccta tgcgctttcg cgttatcggc tgcctttcgg
  1108321 tgaaacgatc cgcacggttg tcgccttgcc gattatcgtg cccggcatca tcgtcggcct
  1108381 ggcgctgctg cgctatctcg tcgtgccgtt caggttcaac atcacgctgg cgcttttcct
  1108441 cgctcatacg gcgctcgtat tgccctatgc ggtgcgtgtc gtatccgcga gcctcaacaa
  1108501 tctgcgctcc gatatcgagg aggccgccgt gctgctcggc tcgtcgcgtg ccggcgcctt
  1108561 cttccgggtg gtgatgccga acatccgcag cggcattctc gccgccttca ttctcggatt
  1108621 cgtcaccagc ttcaaccagg tgcctgtttc gcttttcctt tccgggcccg gcatccgcac
  1108681 gctgccgatc gacatgctct cctatatgga gatcacctat gacccgtcgg tcgcggcgct
  1108741 gtcggcgctg ctcgccttca tgtccatcgg catcgtattt atcgccgagc gtttcctagg
  1108801 attttcgcgc tatgtctagt cccgccttcc tcagcctcga aaaactgacg ctcgcctatg
  1108861 gcgataccgt cgcggtgaag gacctcgacc tgtcgatacg gcaaggtgag ctggttgcat
  1108921 tcctcggacc ttcgggctgc ggcaagacca ccacgatgcg ttccatcgcc ggcctgctga
  1108981 agccgcagtc tggccgtata agcctcgatg gcgccgacat cacccgcgtc gccgcgaaca
  1109041 agcggtccgt cgggctggtc ttccagtcct atgcgctgtt tccgcatctt accgtcttcg
  1109101 agaatgtggc cttcggtctg cggctgaagg gcctttccgg aacggagctc gaatcgcgcg
  1109161 tcgatgccgg gctgaaatcc gtagggctga cgagcttcgc tgcccgcaaa ccggccgagc
  1109221 tttccggcgg ccagcagcag cgtgtggccc ttgcccgctc gatggtgatg gagccgaagg
  1109281 tgcttctgct cgacgagccg ctctctaatc tcgacgcgcg cctgaggctc gaaatgcggg
  1109341 cggaactgca acgggttcag aaggaaaccg gggtcacgat gatcttcgtc acccatgatc
  1109401 agggtgaagc gctgtcgctt gccgaccgca tcgtcgtgat gctgaacggt gcgatcgagc
  1109461 agatcggtac ccccgaggac atctataacc gcccagcctc ggccttcgtt gccgatttcg
  1109521 tcggcttcga gaacatcttc gcaatcgaga acggcagatt gcgtgccgga aacggcccga
  1109581 tcgcgcttgc catgcccttg ccgcatgatg cggcggggct tgcctggcgt ccgcgcatgg
  1109641 tgaccctggg gtcaggtccg ttccagggta ccgtgcgtgg agccgctttt tccggcagca
  1109701 cccgggaata tctgctcgac acgccgctcg gtgctctcaa ggcggaagtc gatgcggccg
  1109761 cgccggcgca ttctgccggc acgacgctcg ccttcgatct gccggtcgag aaggccgcga
  1109821 agctggaaag gttcaattga tccgccatgg gcatctggat cgacacggat atgggtttcg
  1109881 acgacatcgc cgcggtgctc gtcgttcttc acgccgctga gacgatcgac ggggtgtcgc
  1109941 tcgttttcgg caatgttccg ctccagcagg tgaagtgcaa tgcggctggc gcggcgcagg
  1110001 ccttcggctg gagctttccg atccatcagg gacgagcgct tcccgttctc ggcaagcttg
  1110061 aaacggccga gcgcatcctt gggcagacag gcctgccgac ggcgggaccg ggccttctag
  1110121 aagcaccgcc cttgccggaa agcgacgcct ttcttgcgct ctgccgctgg ttggaggggg
  1110181 gcgatggccc gcgccatatc ctcgcgctgg gtccgctcac caacattgct gcgctgactc
  1110241 tcgcgcgccc tgagctggcc gcgcgcatca ccgacctcac ctggatgggc ggcggcgttt
  1110301 ccagcggcaa ccatacggca tccgccgaat tcaacgcctt cgccgatccg gaggcgcttg
  1110361 cgatcgtgct tgctcattgt ctgccactga ggatggtgga cctcgacctc tgccggaaag
  1110421 tcgtagccta tcctgatgat gtggaggcaa tacgcacggc cggtggcgca aacgccacgc
  1110481 tgcttgccga tcttcttgcc ggctatattt cgatcggcac gagccgtgga cgggcgggca
  1110541 tggcgatcta cgacccctgt gcagccgtcg caatggtaga cggaagtgcc atatcctttc
  1110601 aatccgcacg cattgatgtc gagcttgccg gttcgctcac gcgcggcagg accgtggtcg
  1110661 agacccgggc gagccacaca agcttcaacg ctcgattcgc ggtggacgtc gacgccgggc
  1110721 gcgcccgccg atgcctgctc gaggcgcttt cgaaggaagc cgccaaatga atgccataca
  1110781 ggaaccaaac gatctgaacg acgccggctt gcgcgcgcgc gctgtcgccg cggcacgcgg
  1110841 tgatgcgggt ttcgacgtgc tcgtggccgg cggcacggtg gtggatgtcg tgacaggcga
  1110901 atgccgcgcc gcagatatcg gcatcgtcgg cgcaatgatc gcgagcgtcc atgcacccgg
  1110961 ctcacgcagg gacgcgggca cggtcatcga agccgccgga gcttaccttt cgccgggcct
  1111021 catcgatacg catatgcatg tggaaagctc gatggtgacg ccggcggtct acgcttccgc
  1111081 cgtggtaccg cgcggcgtaa cgactgtcgt ctgggacccg catgagttcg gcaatgtcag
  1111141 cgggattgac ggcgtgcaat gggcggtgga tgcgacgcgc ggcttgccgc tgcgtgccgt
  1111201 cgtcctggca ccctcctgtg tcccttcggc tccgcgtctg gagctagccg gcgcggattt
  1111261 cgacgccgcc gccatcgccg aaatgctgtc ctggccggag gtcggcggca tcgccgaggt
  1111321 catgaacatg cgcggcatca tcgacggcga tccgcgcatg agtgcgatcg tcgaggcggg
  1111381 attgaaatcg ggaaaaccgg taaacggcca tgcgcgcggc ctggtggacg ccgatctgca
  1111441 ggcctttgta accgccggcg tcagctccga tcacgagctc gtctcgggcg aggatctgat
  1111501 cgcgaagctt cgcgccggct tgagcatcga gctgcgcggc tcgcatgatc atcttctgcc
  1111561 cgatttcgtg agagtgctcg atgctctcgg gcatctgccg cagacggtca cgctctgcac
  1111621 ggatgacgta tttccggacg atcttcaccg cgatggtggc cttgacgatg ttgtccggcg
  1111681 cctagtgcgc tacgggctca aggccgagtg ggcgctgcag gcggccaccc tcaacgccgc
  1111741 ccggcggctg ggcagggccg atctcggcat gatcgcgccg ggccgccgcg ccgacatcgt
  1111801 cctcttcgag gatctcgggg atttccgcgc cctgcatgta ctcgcaaacg gcagacttgt
  1111861 ggcgagcggc ggcaccatgc tgcaggcggc agccgtggcc gatgtctcgc ccttaggcgg
  1111921 cacaatgaag attgagcggc tgaaagagga cgacttccgc attccagcct gtggcagtac
  1111981 ggctcgcgtc gccacggtaa atcggccgcg cttcacgcaa tggggcgagg tgacggcggt
  1112041 ggtttccaac ggttatgtgg taccgccgga aggcacgacg ctgatcgccg tcgcccaccg
  1112101 gcatggtcgg gccgacagcc gtccacgcgt ggggctgctt gaaggctggg gcacctggct
  1112161 cggcgccttc gcgaccaccg tctcgcacga tagccacaat ctcacggtct tcggcggcaa
  1112221 tccgcgcgac atgatggtcg ctgccaatgc ggtgatcgaa gcaggcggtg gaatggcggt
  1112281 ggtttccgag ggcagggtcg aggcgctgct gccgctgccg ctctgcggcc tcgtctctga
  1112341 tgcgccgctc gccgacgtcg cggcgggctt cgccgccctt cgcgaggccg ccggccggat
  1112401 cgtcgagtgg cagcccccct atctcgtgtt caaggcctgt ttcggagcga cgcttgcctg
  1112461 caatgccggg ccgcaccaga cggatcgtgg aattgccgac gttggaacgg gcaggctgct
  1112521 ggaaagcccc gtcctggaga ccgattgata gcaaattatg aaactacctt gccgtgtctt
  1112581 cgaagaccgc atagcttatg gctttggccg gaaactgtgc tggggttcac atgcgccttg
  1112641 ttccgctgct gcttgcattg cttattgcca cacccgccgt tgccgttgag acttggccgc
  1112701 gttttatgct tgtcgattat attcacgctt ggagcggcac gagcgccgag catatgaaga
  1112761 gccgccggac agtcgtagac tacttgtcgg gtattcgcga ttgcctgtgg tggcagtgcg
  1112821 aatatgaggt gaccatccaa caactgcttc atggcacgaa catgcaaatc aaagcggctc
  1112881 gtatcacgat ggatgatccg gcgctcgaaa gagtcctttc gcaaactcca ttcggagaca
  1112941 tggtgttcct ctctctgcgc aatgagccgc tgtacgggaa accagcgcca tgctcgaaat
  1113001 agcgcgcgaa caatagcttc gcctttgcga tgctttttgc aggcgggatc aaagcggaaa
  1113061 accgcacaca cctttcacca tcccgctctg gctgacgctc gtcaggcttt cagttcctgc
  1113121 tccacgagcg cggtccaaaa ggcggcgccg gggccgatcg cctcgtcgtt gaaatcgtag
  1113181 gcgctgttgt gatgaagcgc gccatccacg gcagggccgt tgccgagcca gacatagcag
  1113241 cccggcgctt ccagcgcgaa gaaggcgaag tcgtcgccag cagtcgaggg cggaaaactt
  1113301 gtcagtgttt tctcgccgaa aaccgaccgg gcggccgaaa gtgcccgcgc cgtcgcatcc
  1113361 gggtcgttga caacgggagg aatgcgccgc tcgaagcgat aatcggcttc gatgccgtgc
  1113421 atcgccgcgg caccctgcgc caaacggccg atctctccct ccaattgatc gcgcacatgc
  1113481 ggtgtgtaag cgcgcgccgt accgccgatc tcgaccgtat ccggaatgac gttcagggct
  1113541 ttcggatcgc cggcttgcag cgagcaggcg ctgacgacgg ccggctgcag cggatcgacg
  1113601 acgcggccga caatcgtctg cagggaagcg agaaacgtgc ccgccgctgt gatcggatcg
  1113661 cggccgagat gcggcttggc gccgtgcgtt ccaatgccgc gaaaggtcag gcgccagctg
  1113721 tccgaggaag caagctgcgg tccgggaacg acggccatct cgttgaccgc aaggcccggc
  1113781 atgttatgca gcccgtaaac ggcatcgcag gggaaaagtt cgaagaggcc gtcttcgacc
  1113841 atgcgcctcg ccccgccgcg gccttcctcg gcgggctgga agatgaaatg gacggtgccg
  1113901 gaaaaattgc gcgtggccgc gaggtggcgt accgcgccga gcagcattgc ggtatggccg
  1113961 tcatggccgc aagcgtgcat tttttcggcc accgtcgact tatagggacg atcggcaagc
  1114021 tccggcatcg caagtgcgtc catgtccgcg cgaagcccga tcgtgcgcgt gccgttgccg
  1114081 acctgcagcg tgccgacgac gccggtcgtg ccgagaccgc gatggacccg gagacccgcc
  1114141 tcttcaagaa gcttggccac caggtcgctc gtccgcacct cctcgaagcc gagttccgga
  1114201 tgtgcgtgca catcacggcg aagcgcggtg agaaaggtga ggtcgtcgat gatcccgagg
  1114261 ggcacgcgca ttggcaggta ttccttgaac ctttgaaagg gcgtgaattc cccagctttg
  1114321 ccagcgggat ttcgtccttt cggtttgatc gaagcggcaa acggtataga tcaaaaatac
  1114381 cgggatcaga actctttacg cgcgccgaat ggacaccagg catgacggaa acgaacagaa
  1114441 tggagccgca cgagttctgg caggaactct ttccacccgc gaccttttcc ggacatggcc
  1114501 gcttcaggac ctctttcccg gccaatcttg ccgacgggcg ccagatactc ctgccgatcc
  1114561 ggccgctttc cgacggcaaa cacgccttgg cctcgctgat cgtcaatcag gcgagtttcg
  1114621 aagtgcagga tgcgctcgcc gaggaactgg cggctcggct ttccgctttc gagccggaaa
  1114681 tcgtcgcagg acttccgacg ctcggattga cgcttgccgc agccgttgcc cgcaagctcg
  1114741 gtcacaagcg ttatgtacct ctcggaacgt cgcgaaaatt ctggtacgtc gaagaccttt
  1114801 cggtgccgct gtcgtcgatc acaacgccgg gccagaaaaa gcggctctat gcggacccgc
  1114861 gcatgctgcc gctcttgaga aaccgcaggg tcgtcctgat cgatgacgtg atatcgagcg
  1114921 gtgcctctat cgtcgctggc ctgtcactca tggcgtcgtg cggggtcgag ccggtcgcca
  1114981 taggtgccgc catgctgcaa tcggagcggt ggcgccagcc gctcttcgac ctgtccgcgc
  1115041 aatggcccgc ccggactgtc ggcgtcttcg caacgccgat gctcgtccgg gcggaagatg
  1115101 gcacatggac ggcggcggaa tgacgcgcgg cgagcaaact gtgtgctgct tcagcccgca
  1115161 ttccacgcct gaactcatgg tgagctaggc acgcggacgg acctgataga acagcctcgg
  1115221 cgtcgcttcg gacttgccga aggcatagac atcataggaa gcgttcgggc tgtctcccat
  1115281 gccgatggag ccctctggca tgcccgggac cgcaagccct gcaatcgcag gccgctcgtc
  1115341 cataagcttc ccgatggctt cgggcggcac atggccttct atgacgtagc cctcgatgac
  1115401 tgcagtatga caggcctcca gatccgccgg aacggcgaag cggcgcttga tcgccgccat
  1115461 gtctgcttcg ttgtgcactt cgactgcgta agccgctcgc ctcatcgcct cggcccagct
  1115521 ctcgcagcag ccgcacaacg ggtctttgta gatccgcatg tggcccttgc ctgcaattgc
  1115581 ccaacgcgtg ccggtcgtca acgcaacaaa gcccatcaga gcggtcagga attctctgcg
  1115641 ggaaaggggc atggcgcact cccagtaggg ccgcaaaccg tgtttgatcg tccagcataa
  1115701 tgcggattga gcgggcgtta aaccgcgaat ccgagcgact gaagctttta aagtcccttt
  1115761 cttatgcact ggaaaacttg aaagtctttc gttcccgccg tcgaaatcga cggctagcga
  1115821 acatgcgcgt gaagacgcac aatccatatg cttgcgatgg cgatccatcc ggcgaggccc
  1115881 atggcctgga tcaagccgcc tgaaaaatga caggcgcgcg atcaaaatgc aatggccggg
  1115941 ctcttggagg agcataacac ccggctctgt cgttcggctg cgtcgagatg acgtctgcca
  1116001 agggaggaaa aatgtttgaa cgactcttca agctcaagga gcacggcacg accgtccgaa
  1116061 cggaagtaat cgccggcgtc acgacgttcc ttacaatgtc ctacatcatc ttcgtcaacc
  1116121 cggatattct gtcgaccacg ggcatggacc gcaacgcgat ctttgtcgca acctgtcttg
  1116181 cggccgctct cggatccgcc gtcatggcgc tggttgccaa ctggccgatc ggcatggcgc
  1116241 cgggcatggg cctcaacgcc tttttcgcat tcacggtcgt cgcggccctg ggcttcacct
  1116301 ggcagcaggc gctcggcgcc gtgttcatct ccggtattat cttcctgctt ctgactgtta
  1116361 ccggtgtccg aagctggctg attgcgggca taccgcactc gctgcgaagc gcgatcgcaa
  1116421 cgggtatcgg cctgttcctg ggtataatcg cgttgaagaa cgccggcatc gtcgtcgaca
  1116481 acccggcgac tctggtcggc ctcggcgatc tgaagcagac cgggccgctg ctcgcaattc
  1116541 tcggcttctt cgtcatcgcc gttctcgacg cactcaatgt tcgcgggtcg atcctcatcg
  1116601 gcatactggt ggtgacggta ctctcgatgt ttctcggcgt atcggagttc cagggcgtgc
  1116661 tgtccgtacc gccgagcatt gcgccgacct tcctgcagct cgacatagcc ggcgctttac
  1116721 atggcggcct cgtccacgtc atcctcgtct tcgtgctcgt cgaggtcttc gacgcgaccg
  1116781 gtacgctgat aggtgtcgcc aagagggcaa aactggtgga agagggtaag cccagccgtc
  1116841 tcgggcgcgc cctgctcgcc gatagctcgg caatcgtcgc cggttcactg atgggcacca
  1116901 gcagcacgac cgcctatgtc gaaagcgctt cgggcgtgca ggcgggcgga cgcaccggcc
  1116961 tcacggcgct gaccatctcg gtgctcttcc ttgcagcact cttcatttcg ccgctcgcgg
  1117021 ccgccgttcc gacttatgca acggcgcccg cgctgcttta cgttgccggc ctgatgatgc
  1117081 gcgaactgac ggaaatcgag tgggacgatc tgacggaggc ggcaccggct gcgctcacgg
  1117141 ccatcgccat gccctttacc tattcgatcg caaatgggct cgcattcggc ttcgtaagct
  1117201 atgtcgtcct gaaggtctgc accggcaagt ggaacgtcat tcatccggcg acccagctag
  1117261 tcgctgccct cttcgtcgtc cgcttcgcgt ttttcgccga gtgacattgc tgaaggggtt
  1117321 ggagagggtg gcgaccggcg gggccccctt ccgaccccgc tacggatttt gacgagccga
  1117381 caaacctctg gcgttcttac cgggcttaga tacatgctcc tcgacctcgc ggcgtgcgac
  1117441 cgagttggac ttgagtaacc catcacgcta ggttacttgc gcttatggtc acgcagcttt
  1117501 ggatagtggc cggatagcgc gtgagacaga gccgcgtgtt gcatcggtgc gctagacaag
  1117561 cgaagcggcc gcatcgttgt ggcgttgacc aatggctgca cgttcgcctt cccgccacgt
  1117621 ctggcacagg gactggaaga ggcgagcagc gaccagctcg ccgcagtcga gatccttggg
  1117681 cacggctatg gcctgcatgg gggggattgg acgtcgatct ctcgattccg ggtcttctat
  1117741 ccggcatatt cggcaccaaa gcttacatgg cgcggcgggc agggcaggcg acatcgccgg
  1117801 cgaaggcagc agccgcgcgt gccaatggtg ccaagggcgg ccggccgcgc gaatcggccc
  1117861 gtggctagtt agagccggat ggaagggaat acggtttccg cccgcattcc gtctaagctt
  1117921 cgtggaggaa ccgcccggat gttcatcata ttcgcaggtt tgcccggcac ggggaaaagc
  1117981 accattgcgc agacttgcgc tggccggctc ggagcgacct atctgcggat agactccatt
  1118041 gaacaggcca ttcggtcctc cggcattttg ggcctgcaat tggatgtcgg gccggcaggc
  1118101 tacatggccg cctatcgtgt cgccgctgac aatcttcagt tgggacatac tgtgattgcg
  1118161 gactcggtca atccgctccg cattacacgc gaggccttcc gagggatcgc ggagaaggcg
  1118221 caggccggct tcctggaggt agaggtggtt tgctccgaca agagcatgca ccagcaacgg
  1118281 gtggaaagcc ggcattccac cgtcaatggt ctggtgttgc ccagctggga agaggtggaa
  1118341 acacgacact acgagtcctg ggaaggcccg cgcctggagc tcgactcggc ccgtttttcg
  1118401 gtcgcccaat gtgtggaaag gatagtcgag gctgcgaggc tgcgccggcc gcgataatgc
  1118461 acggcgcgca tccgaccagc cttggttcca ttcgtttaga aaggcctgtt gagattcatc
  1118521 ttgagtttat gaaggctgct gtgcggtgga tgattagcgt tggagctctg gtttgtcggc
  1118581 gcgtatggcg atgcgctaga attcccttga gtgccggctg cgcggcctgg gaaacggatc
  1118641 gcagggccgc ggtcgttctt cttccctcat tttctgtgct cgtcacagaa atccagcagc
  1118701 gccgcgtctg cggcgcggga agagttcttt cagcccaagg acttggtctg gctggcaact
  1118761 gtgacgagca catgaatgag gaaatcaagc aagtcgcggc gggcatcccg attctcaaca
  1118821 gcccatagag cgggatcagg aataatgcgc ggtttttcgc ccgcatcccg ctccgactta
  1118881 ttgcgccccg gtattgtttc gcatcactcc ggcagcattt cgcggagccg caacaacgcg
  1118941 atccgttcta cctggaggca tgccgtattg aattcggctt ttccatcatt gccgatgcgg
  1119001 gtctcgaagg ccgcgaggat ctcgtccttg ctgcgcccct tgacggccat gatgaaagga
  1119061 aagccgaatt tctcgacata ggcatcgttg agcgcagtga aacgctcgcg ctcctcgtcg
  1119121 gtcagcgcgt cgagccccgc ggaggcctgc tccgaagtcg agctctctgt cagccgcttc
  1119181 gcctgggcga gcttgccggc aagatccggg tgggcgttca ggaccgccag ccgttcctct
  1119241 tcgctcgctt cacggaagac cgcacaaagg gccgcatgca gtcccgatgc cgtatcgtta
  1119301 gccggtgcga gttcaccggc aaaggcgcgt ctggcgatcc agtccgagtg ctcgaaaact
  1119361 ccaccgaatc gagaaatgaa gtcatccttc gagagccgcg acggtcggtt ttcgttcggc
  1119421 cggaacggat aggcctctgc ccagtagcgg gcaatgtcga tgcggcgtgc gacccagact
  1119481 ttctcgtggc ccttcacgta atcgaggaag cgcgccagtg cggccgcgcg gccgggtcgg
  1119541 ccggctagac ggcaatggag gccgatgctc atcatcttcg gtgcgccggc ggtaccctcg
  1119601 gcatagagaa cgtcgaagct gtccttcaga tagctgaaga actgatcgcc gctgttgaaa
  1119661 ccttgcgggg tcgcaaagcg catgtcgttg gcatcgaggg tgtatggaat gacgagctga
  1119721 tgccggccgg catgctcatg ccagtagggc aggtcgtcgg cgtaggaatc agagacgtag
  1119781 tcgaagccgc cggcttcggt cacgaggtcg agcgtgttca cggagcagcg ccccgtgtac
  1119841 cagccggtcg gcccctttcc ggttacgatc gtgtggaggc ggatcgcctc ggcgatctcg
  1119901 gcgcgctcgc gctcggcgtc gaaatccttg tgctcgatcc atttgaggcc gtgggaggcg
  1119961 atctcccagc cggcttcctg catggccgcc acctgggcgg gcgagcgctt gagggcagtg
  1120021 gcgacgccat agacggtggc cgctatttgt ctctcggtga aaaggcggtg cagccgccag
  1120081 aagccggcgc gcgcaccata ttcgtagatc gattccatat tccagtggcg ctgggcaggc
  1120141 caggcctgag cgccgacgat ttccgagaga aaggcctccg aggcggcgtc gccgtgaagc
  1120201 acgcaattct ctccgccctc ctcgtaattg atcacgaatt gcacggcgat ccgggcgcca
  1120261 tcgggccagg caatatgcgg gttcggacca tggcccagga gatcgcgggg atatctcata
  1120321 acagcagctc ctccagagat tgtcttgtcg tccaattggt agcgagaatt ccgatctccc
  1120381 attccccccg aaaaatttga aagtctcgaa ggttgagccc gctacacaaa ggtcctcgcg
  1120441 cttcggatac tctatcctcg aagctgactt tcggaggagc gatagaatgc aagttcaaga
  1120501 cggaacgtcc ggccgcttga cgacccacgt gctggacacg tcgagcggca aaccggcaag
  1120561 caatctgcgc atcgatctct accggattga aggtgaacgg acagagcttc tctcgtcgac
  1120621 acgaaccaat gacgacgggc gatgcgatgc gccgcttctc aacggctcca cgatggaaac
  1120681 cggaacttac gaactgcgct ttcacgccgg cgaatatctc ggccccgggg cggagcgcga
  1120741 ggtgaacccg tttctcgatg tcatcccgat ccgcttcggc atcgccgacc gggctgcgca
  1120801 ctatcacgtg ccgcttctgc tttcgcctta cggctattcc acctatcgcg ggagctgacg
  1120861 gcaatgacca tcgaattccg aaatacgatc cgtttccttt tgaatgaccg gtccgtcgag
  1120921 cttgccgacg tctcgccggt gcagacgctg ctggacttcc tgcgtatcga ccgcaatctg
  1120981 cgcggcacga aagaaggctg cgcggaaggc gattgcggtg cctgcaccgt acttgtcggc
  1121041 cgcctcctcg acggcaagct ccgatacgaa tcggtgaatg cgtgcatccg cttcgtcgca
  1121101 tcgcttgacg gctgtcatgt ggtgacggtt gaagcgcttg cccagccgaa cgggccgttg
  1121161 catccggtac agcaggcgat ggtagacacg cacgcctcgc aatgcggttt ctgcacaccc
  1121221 ggtttcgtga tgtccctcta cggtctctgg atggccaacg cgaagccgag cattcagcag
  1121281 atcgagaagg cgttgcaggg caatctctgt cgttgtaccg gctatgcggc gatcattcgg
  1121341 gcggccgaag cgatcgcatc ggtgggtgag ctcggcaagg acccgctgat tgtggaacgc
  1121401 gagcaaatca cgcgacaact gaaggccctt caagacggtc gccgagtgga gatcgggggc
  1121461 gaagacgagc gcgtcgtgct gccggcctcg ctggacgatt tcgctgcggt tctccaggcc
  1121521 aaccccaagg cgacgatcgt cgccggttcg accgatgtcg ggctctgggt taccaagttc
  1121581 atgcgcaaca tcgcgccggt cgtgcacctc tcgcatctgg aagagttgcg gcggatctcg
  1121641 gtcggggtgg atgggatcac ccttgctgcc ggcgtaagct acacggaggc ctacccggcc
  1121701 atcgtcaggc acttcccgca actgcgcgaa ctctgggacc gtatcggcgg cgaacaggta
  1121761 cgcaatatgg gcacagtcgg cggcaacatc gctaacggtt ctccgatcgg cgacacgccg
  1121821 cctgcgctga tcgcattggg cgcttcggtc accctgcgca agggaacaaa ccgccgtacg
  1121881 ctgccgctcg aagccttttt cctcgaatac ggcaaacagg atcgcgaatc cggcgaattc
  1121941 gtcgagtctg tccggattcc cttcctggac gagacgcacc gcttcgccgt ctacaagatc
  1122001 tcgaagcgat tcgatgaaga catttccgca gtctgcggcg ccttccgcgt gaagctcgac
  1122061 ggagacggca gggttgccga tgtggctatc gcctttggcg gcatggccgg cacgccgaag
  1122121 cgcgcccgga atgtggaagc cgctctcaag ggcgcgcaat ggaacgacgc tgccgtcgaa
  1122181 gctggcgtcg ccgccttcga gcgcgatttc gcgccgctca ccgactggcg tgcctcttct
  1122241 gaatatcgga tgctcgttgc caggaatctc ctccggcgct tccatctgga aacgcaggag
  1122301 acgcgccatg tccggatcga ccgcacggtc gcggtggcta tgtagagagg gtggacccat
  1122361 gaatgtgatg cagcccgtcg tccgcgtccg cggcgccgtc cacgacaagg aacgccacga
  1122421 atccggtcac aagcatgttt ccggaaccgc agaatatatc gatgacattc cggagcccgc
  1122481 gggtacgctt cacggctatc tcgggctctc gcagcgcgct catgccgaaa tcctgtccgt
  1122541 gaatttcgag gcggtgcatg acagtcccgg tgtcgtgggt gtgctcacgg ctcaggacat
  1122601 acccggcgaa aacgatatca gcccggcgca caaacacgac gatccggttt ttgcgaccgg
  1122661 cagggtcgag ttccacggtc agccgatctt tgcggtcatc gccacgtcgc gcgaggccgc
  1122721 ccggcgcgct gccgccaagg tgaagatcga ctatcgcgat ctgccgcatg tgacggatgt
  1122781 tctcgaagcg gcggctgcga actatccgct ggtgatcgat cccctgaagc tcgagcgtgg
  1122841 cgacatcgat gccggctttg ccaaagcgaa gaacatcgtt tcgggcgaaa tgcgcatagg
  1122901 cggtcaggac cacttctacc tcgagggcca aatctccttc gccattcccg gtgaggatga
  1122961 cgaagtgacc gtcttctcct cgacccagca tccgagcgag acgcagctca tggtcgccca
  1123021 tgttcttggc gtgccctcaa atgcggtgac cgtcaatgtc cgccgtatgg gcggcggctt
  1123081 cggcggcaag gagacgcagg caaatctttt cgcggcggtt gcggcagtgg cggcaaggaa
  1123141 gtaccgccgt gcggtcaagg tgcggcccga ccgcgacgac gacatggcgg caaccggcaa
  1123201 gcgccacgac tttcacgtcg actacaagat cggcttcgac gatgatggcc gaatcgaggc
  1123261 ggtggacgcg gttttcgccg cacgctgcgg cttctcggcc gacctttccg gaccagtgac
  1123321 ggatcgtgcg ctctttcacg ccgataattg ctatttctac ccgaatgtcc ggctgcgctc
  1123381 gcgcccgctc aagaccaaca ccgtgtcaaa tacagcgttt cgcggtttcg gcggaccgca
  1123441 gggcatggtc ggcggagagc ggatgatcga agacgtagcc tatgcgctcg gcaaggaccc
  1123501 gctcgaaatc cgcaagctca atttctatgg cggcgaaggg cgcaacctga cgccgtatca
  1123561 ccagacggtc gaagacaaca tcatcgggcg gatcatcgag gaactcgaaa cctcgtctga
  1123621 ttacgccgca cggcggaagg cgatcatcgc cttcaaccgc gagaaccatg tcatcaagcg
  1123681 cggcatcgcg ctgacgccgg tcaaattcgg catctccttc accaagaccg agtacaatca
  1123741 ggcaggcgcc ctgatccacg tctatacgga cgggtccatc cagctgaacc atggcggcac
  1123801 cgaaatgggg caggggctct ataccaaggt cgcccaggtc gtagcggacg agttccaggt
  1123861 tgatctcgac catatcaagg tgacggcgac ctcgaccggc aaggtgccga acacctctgc
  1123921 aacggctgcg tcgtccggtt cggacctgaa cggcatggcc gccgcaaacg cctgccagca
  1123981 gatcaaggag cggctcgtgc gcttcgcggc cgaacgctac ggcgtgagcc aggccgatgt
  1124041 cgctttcgag ccaaacacgg ttcgaatagg ggccgagcgc atcccctttg cggatcttat
  1124101 caaggcagct tatgccgcgc gcgtgcagct ctcggcggcc ggcttctaca agactccgaa
  1124161 gatccattgg agccgcgccg aagggcgggg ccggcctttc tactatttcg cctacggcgc
  1124221 ctcatgctcc gaggtcagcg tcgacacgct gaccggcgaa taccaggtcg aacgaacgga
  1124281 catcattcac gacgtcggca agtcgctgaa ccctgctctc gacctcggcc aggtcgaagg
  1124341 tgccttcgtc cagggcatgg gctggctgac gaccgaggaa ctctggtggg atgccaaggg
  1124401 ccggctgcgg acgcacgcgc catccaccta caagatcccg ctcgcgtccg atcgcccgcg
  1124461 cgtcttcaac gtgcatctgg ccgattggtc ggtgaaccgg gaggagacga tccggcgctc
  1124521 gaaggcggtc ggggaacctc ccttcatgct aggcatttcg gttctggagg cgatatccat
  1124581 ggcggcggca agcgttgcgg actatcgtat tccgccgcgc atcgatgcac ccgcaacacc
  1124641 ggagcgcgtt ctgatggctg tcgagcgcct gcgcgccgcc cgggccggtt agggacaatc
  1124701 gcgcagggca gatagtggac gactgaaatg acgggtagaa aggacatccg cgatttcctg
  1124761 agccgtgaac cggcctgcgt gcttgtccag gtggcgagcg ccgcaggctc gacgccgcgc
  1124821 gatacggatg cctggatgct cgtctcaaag gatcgcacct tcgccacgat tggcggtgga
  1124881 cagttggaat tcatggcgat cgaccacgcg cgcaagctcc ttcatggggc gaacggggac
  1124941 cttcgactgg cgatccccct cggccccgag atcggccagt gctgcggcgg tcgcgttacg
  1125001 ctttccttca aaaggttgga tgcggtcatg cgagctgcaa tcatcgaatc cagcgacaat
  1125061 gagatcgcgc gccgaccgca tgtctacatc ttcggcgccg gccacgtcgg caacgcgctc
  1125121 gcccgggcgc tttcgcatgt gccgctcagg accgtgctcg tagacacccg cgagcatgag
  1125181 ctctcggccg ccgacgcgcc tgacgtcgag acctgcctga ccgcaatgcc cgaggctgtg
  1125241 gtgcgcgacg cgccaccggg cagcgccttc gtcgtcctta cccacgatca cgcactcgac
  1125301 tttctgatca cgactgaggc gctcgggcgc gaagacgcca gttatgtcgg catgatcgga
  1125361 tcgaagacga aacgcgcgac gttcaagaac tggctatcgc gagaggtcaa tcgtcccgag
  1125421 cttttcgaga ggctcgtttg cccgatcggc ggtacggcgg tgaaggacaa gcggccggaa
  1125481 gtgatcgcgg cgcttgccgc ggccgaggta gtgactgcgg cgctgaaccg ccatttgcag
  1125541 cctcgcgcgc cctctccgaa gagccagaga tcggtcaagg cttaggccga ccggcagatg
  1125601 acacgcatcg gcgatcgaga gccgccgaac gacgggcaag gtcgtgcttg ttcgttggcg
  1125661 gcgctgcgct caagcgctgg aacgctccgg tacttcagca ggctcagcca gcatcttgcc
  1125721 tatcagccgc tgacagcgct cggccatgaa gtcgatcatc agacggactt tcggatcctg
  1125781 gaagcgtttg tgcggataga tcgccgcaag ctgcgcgccg agcggcggcg tctcctcgag
  1125841 tatcggcacg agcaggccct cgtcgatata gtgcttcacc tcgaatagcg gcttgttgac
  1125901 gatgccgcgg ccgtcgagcg cccattgggt aagcacgtct ccgtcatccg aatcataggg
  1125961 cccggcgact tcgaacttgc ggacgccatc cggcgtctgc aaggtccagt aatattcctt
  1126021 cgacccggga tagcgcagca gaagacagtc gtggctttgg ctgaggaggt cgtccggcga
  1126081 cgagggcgtg ccgcgccttt cgaagtagcg cggcgagcca cagagcacgc ggtcgcagtt
  1126141 catgatgccg cgcatgcgca ggttggaatc ctcgagtatg ccgagcttga aggcgatgtc
  1126201 gacgccttcg gcgagaatgt cgacattatg atcggagagg cgcagcctga cttcgatatc
  1126261 cggatagcgg tcatggaact ccgggattcc gggcgcgatc aggcggcggc cgataccgag
  1126321 cggagcggtg atcttcagcg ctcccttcgg atttcttgaa agatcggcaa tggcgctttc
  1126381 cgcctcgttg accgcttcga ggatcttcac cgcgccttcg tagaagactc gtccgtgctc
  1126441 ggtcggcgtc agttttcggg tggtgcggtt gaacaggcgc acccccatat gccgctccaa
  1126501 ctctttgatt ctgttgctgg caaccgccgg cgtaacacgt tgatcacggc ccgctgccga
  1126561 cagcgttccg agctccacga cgcgcacgaa cacacgcaca ttatcgagat aggacatgct
  1126621 tccgcctctg ttcttccggc gcgaacgtaa cgctccggcc tctcttcgat tttatagttt
  1126681 tttttgaaag agttggtgcg atgtcgccgt tcccgcctcc ccaagcaatg acacataatg
  1126741 aatgcgagag aaatggggag aactcaatgt acgagtatgc catcgcctgg gattggctga
  1126801 catttgcggt gagatggctg catgtcatca ccggcatcgc ctggataggc tcatcctttt
  1126861 acttcgttgc gctcgacctg ggcctgaagc agcgtccggg cctgccggtc ggcgcctatg
  1126921 gcgaagagtg gcaggtgcat ggcggcggtt tctaccacat ccagaaatat ctggtggcgc
  1126981 cggcaaacat gccggagcac ctgatctggt tcaaatggga atcctacgtc acctggctct
  1127041 ccggtttcgg catgcttgcg ctcgtctatt atgccggcgc ggacctctac ctcatcgatc
  1127101 cgaacgtgct cgacgtttcg aagccgatgg cgatcgccat ctcgctcgcc tcgctcggct
  1127161 tcggctggct cgcctacgac atgatctgcc gatccccatt cggcaatgac aatacgcggc
  1127221 tgatggtgct gctctatttc attctcgtcg ccgtcgcctg gggttacacc cagctgttca
  1127281 cggggcgtgc cgcctatctg catctaggcg ccttcacggc gaccatcatg tcggcgaacg
  1127341 tgttcttcat catcatcccg aaccagaaga aggtcgttgc cgacctgatc gcaggccgca
  1127401 cgcccgatcc tgctctcgga aagcaggcga agcagcgttc gacgcacaac aactatctga
  1127461 cgctgcccgt gctgttcctg atgctgtcga accattaccc gctcgccttc ggcacgcagt
  1127521 ataactggat catcgcctcg ctggttttcc tcatgggggt cacgattcgc cactggttta
  1127581 acacccgcca cgccaacaaa ggcagcccga cctggacctg gctcgcgacc gtgctcctgt
  1127641 tcatcgccat catgtggctt tccaccgtgc ccaaggtcct ctccgagggc ggagaggcaa
  1127701 gggcagcgac ggcggccgag gcggtggtcg cgtctccgga tttctccaaa gtgcgcgaca
  1127761 ccgtgcttgg tcgctgttcg atgtgccatg cgcgggagcc cggctgggag ggtatcatcg
  1127821 tgccgccaaa gggcgtgatc ctcgaatccg acggcgacat tgttgcgcat gcccgtgaaa
  1127881 tctacctgca ggcggggcgt tcgcatgcca tgccgcctgc caatgtcacc ggcatcaccg
  1127941 aggaggaacg ccagctcatc gcctcctggt acgagaggac gataaaggaa ggaaaagtcc
  1128001 aatgagggat ctcttgatcc gcggccgggt gctgaccttt ctcaaagagc cccagggcat
  1128061 cgacgatacg gcttcttacc gcttcatcga ggacggcgcc gttttcgtaa ggagcggcaa
  1128121 gattgtacac atcggccctt acgttgacgt ggcgaagcag gcaggacctg acacagaggt
  1128181 cgccgaccac cggccgcatc tggtcctgcc cggcttaatc gacacgcacc tgcattttcc
  1128241 gcagacccag gcgatcgcct cctacggcgc gcagcttctg gaatggctga acacctatat
  1128301 cttcgtggaa gagcagaagt tcaaagctcc ggagcatgcc gccttcatcg cgggccgctt
  1128361 catggacgag ctcctgtcca acggcacgac cacggccgcc gcctattgct cggtgcatcc
  1128421 ggaaagcgtc gacgccttct tcgcggcggc cgaagagcgc gacatgctca tgatcggcgg
  1128481 caaggtgatg atggaccgca acgccccgga cgcgctgcaa gacacgtctc aaaagggcta
  1128541 tgacgagacc aaggcgctca tcgcgagatg gcatggccgc ggccgcgcgc attatgcgat
  1128601 caccccgcgc ttcgccatca cctcgacgcc ggagcagatg gagatgagcc gcgccctcgc
  1128661 cgcagagcat ccggactgct acgttcagac gcatctgtcc gaaaaccggg acgaaatcac
  1128721 cttcgccact tcgctctatc cggaagccaa ggactatacc gatatttatg ctcgctatga
  1128781 gcttctcggc cgcaagaccc tgctcggcca ttgcatccac ctgagcgacc gcgaaatatc
  1128841 ggcgctcgcc gagacggagg cggtgggcgt cttctgccca acgtccaacc tcttcctcgg
  1128901 cagcggcctc ttcgatcgcg accgcttcga caagcttgga gcacgccatg cggtcgccac
  1128961 cgatgtcggc gccggcacaa gcttctcgat gctcgaaaca atggatgaag cctacaaggt
  1129021 actgcacctg caggggcagc ggctctcccc tctcaattcc ttctatatga tgacgctcgg
  1129081 caacgcgcgc gcgctcgatc tcgaggatcg catcggctcg ctgcacgccg gcgcggatgc
  1129141 ggacatcgtt gttctcgaca gccgagccaa gccggccatg gaactcagga tgcaggtcgc
  1129201 ctcgtcgctt gccgaagagc tgttcatcgt gcaaacgatg ggggacgacc gttcggtggc
  1129261 tgaagtctac gtggccggta agccgatgaa atgccgccgc cggcagacga aagctcaggc
  1129321 ggacgtcgaa ctggcaacgg catgaacgtt gcagaagtcg ccttgatcaa tagtttcaaa
  1129381 agccattgta gcgcattgat ttggtgcggt tatgacgctt tcccggcaag cagagaaagg
  1129441 gaaccccaga gggtgccgct tgtcctttcg ccacgcctgc ggaaagaaaa cgccgacagg
  1129501 cggttggggg gctgccgccg ctactgctga gggatacgcg ggaaaattgc gcccgccctc
  1129561 cctctcgatc tcctggaact gaagcgcccg cgggcgccgg cgcttcagtg ccgtcggcat
  1129621 acgcagctac gctgcgtgct tttcgccttc tatctgtttc gaggattcgc cgcccggcag
  1129681 tgcttctgcc tgctgtatct cgattcgacg cggcttcatc tgctctggaa gctcacgaac
  1129741 gagatcaatc ttgagcatgc cgttggcgag gttcgcgccg gttacggtga cgaagtcggc
  1129801 gagctggaat cgacgctcga agctgcgtgc ggcaatgccg cgatagaggt attcggtgtc
  1129861 gtcttccccg gctttcgcac cggtgatggt cagcatctgc tgctcgtgcg tgatggtgat
  1129921 ctcgtccggg gcgaagcccg ctaccgacat tgcgatccgg tactggttct caccgacacg
  1129981 caagatgtcg tagggcggcc aattgtcgcc aggtgccagg cggcttgcgg aatccaagag
  1130041 gtcgaacaga tgttcgaagc caacgctgga gcgcgacagc ggcgagaaat cgaagcttgt
  1130101 tctcatagcc atatcctcct tgagcaacat ggacgatgag gagcgccgaa gagaacggtg
  1130161 cccctcgact tgcgaacccc ttacaggcgg ctcttgcacc cgatttagtc attcggagcc
  1130221 gggtttcaag ggcctccgcg acttgatttt cgccgctgtc cgggtccccg gcggaggcga
  1130281 aaatcggcgt tcagaacgag ggccaaagct ggtgatcgag gttcttgaat ttaccttttc
  1130341 cgctccaata tctatctgga tcgggctgag caacgcgggt gcggtgttcc ggcccgcatt
  1130401 tcattgacgg cataggaaag gaggaagaaa tgcttctcaa tgagatcccc tggacgatcc
  1130461 ctctcaccgt gcgcctttcc aacggtctga cgcacagttt tgcctccgtg tacgaggctc
  1130521 tcgacttcct ggaaaacgaa tggcccctca ggaggggcga gcgctacgaa cgcgcggtgc
  1130581 ggacgtgccg gcgggcgttg aaccggatga cgccggcggc agtggcgcgg gaagccttca
  1130641 tcgccgcttg ccttgaggcg gggatgccgc tcgtcatgac gccaccggcc caaaagccgc
  1130701 aaaccggcat cgtcaaggct gcgcagtcag cctaaggccg gacgctcgcg tcgtttcact
  1130761 ggacgaagac gcgaacactg gcggcccgac cgagcgcgtc gataacggtg agtgtcgagt
  1130821 agccgccgcc atccggcagc cagcggctga cccgccggcg cgttgcctcg ggtagcggac
  1130881 gaccattggc cagccagcgg aagggggccc gaccgccctg gagctttagc gtcaaggggg
  1130941 acatcgctgc ctggcccctt acgctgagct ctacgtgagc accctcgggc gggaacacga
  1131001 tctgtggagc cggctcccga gccgaggctg caagcagacc gttcgcattg atggagaacc
  1131061 gccgctggct gaccggcaga tcggcctggg caagccggac agcacccgcc ggcgggccgg
  1131121 gcagcggcgt cgtcccaatc ccggccttga caaaaccctc gaaaaggatt ggggcggccg
  1131181 caccgtaacc ggtgagaccg ggcaccgcgc cattgtcggg cctgccggcc cagacaccaa
  1131241 gcacatagcg gccgtcgaac cctacggacc aggcgtcgcg atagccgtag ctggtgccgg
  1131301 tcttgtaggc gataccgcgc cgacggcttc ccgcgggcgg cagcacgtcg gagagaatgt
  1131361 ccgcgacatg ccaggccgcc actgttgaca ggagcggttc gccgtcgatg ggaccaggaa
  1131421 cgccttcgac gccgttgccc aggcgcaccg gtatgccgtg gtttgccagg cccgcataga
  1131481 gctgcaccaa ctcgcgaagc gtgatgccca ctccgcctag cccgatcgca aggcccggtg
  1131541 cttcatgtgg cggcagtctc ggccggatgt cggcacggcg gaagcggacc atcagtcgcg
  1131601 atggtcccac ggcgtcgagc aggcggatcg ccggcacatt cagggaaagt tgcagcgcct
  1131661 gccgcacgct gacatcgccc tggtagctca tgtcgaaatt gcgtgggcgg tagccgaaga
  1131721 agtccgccgg ccggtcttcg acgatcgtct cctgactgac gagcccctct tcgaacgcaa
  1131781 ggccgtagat gaagggtttc aacgtcgatc ccggggagcg ggtgatccgc gtcatgtcga
  1131841 tccagccgga ccggcttgcg tcgaaatagt ttgccgagcc gacctctccg acgatttcgc
  1131901 ccgtcctgat gtcggccatg accatggcga tcgacacctt tgagccgagc tttacggcac
  1131961 tctctctcgc gaccgtttcg agcccccgct gaacattacg gctgagcgtc gtcggatgct
  1132021 ccagggccgc cggatccttc cgacgtgccg cctccgccag atgggcagca tggactggaa
  1132081 gctgaagtcg gcgtgtcggt atggcggtca tcgccgctcg ctccgcttct ccatcgccaa
  1132141 tgactttggc gactgcagcg cgggcgagca cacgtttgcg ggccgcctcg gcggccgcca
  1132201 gattgcggtc gggccgccgc ttttccggca attgcggcag cgccaccatc agtgccgcct
  1132261 cgcccgccga aagacggcgc ggctccttgc cgaaccaggc gaggcttgcc gcacgtacgc
  1132321 cctcgaggtt gccgccatag ggcgcacggg tcagatagag gtcgaggatc tcgtccttgt
  1132381 cgagacgccg ttcaatctga atggcacgcg cgacctgcag gaacttcgct gccagcgtcc
  1132441 gccgctcgcg gggctctata agccttgcaa cctgcatgga aagcgtcgag gcacccgaaa
  1132501 cgatgcggcc attggtgagg aattgcagcg ccgcccgtcc aagcgccagt gggtcgacgc
  1132561 cgcgatgttc gcgaaagcgt tggtcctcat aggcgatcag catctcgatg aagcgcgggt
  1132621 cgacgtcctc cacggttgtc ttcagccgcc ataagccacc ttccgttgca aaggcgcgca
  1132681 ggagatggcc gtctctgtcg aggacttcgg ccgagaccgt tgcagcctcg gagaggggcg
  1132741 ggggaaaggc cctgtcggcc cataagaggg cgatggctgc gagagcggat acagcgaggg
  1132801 caataggcac tgcgataacc acccgtcgta gtcgggacgg ccgggctctg cctttgcggt
  1132861 tcactgttcg ccggaaggac gtcatcgggc gttctactgg actgccagca cctccatgcg
  1132921 gcccgtcgcc gtacgggccg agaactgcgg ccgatacatg tcctcgacgc ttgcagcagg
  1132981 gtggtcgtag gtgccgggcg tcaccgcgcg gacgacataa gcgagcgtga tctcgcggtt
  1133041 gtcgccggtc gagcggttga acgcggccac gaagcggtca ctgcggaact ccgtatgagc
  1133101 agcttcgact tcgccgatcc attcgaagtt cgcaagctgg gcgctgtgga cgagacttgg
  1133161 attgtcgatc tcgaagccgg cgggcaggag atcggtgatg agcaatcgag aaggccaatc
  1133221 gttgctctcg gtcaccttga gcaccgccac atagcgttcg ttctgccgta cctggctgac
  1133281 attgaccgca gttccgtcga gtgtgtaata ggtccgctcg atggtgaagc cctcgccgcc
  1133341 tgccgagagc ggctgtgccg gagccgcaac ggtggtcact acggcggaaa ccgcatcggc
  1133401 gccttcgttg cggatcacga cggggtgttc gatcaacgca tcgccagtaa tgcgcgcggc
  1133461 gtagctgccg ctacgttggg cgccatttac atctaacctc atatcttcgt cgccgccctg
  1133521 gatggcgcgt gccgccagta gcatccaagt ctgttcctga gtgctcgtat atttcgcctg
  1133581 ctgccactca cgggcgacga tcttggatag ttccgggatg acaggcggaa cggggcggct
  1133641 ctcggccgcg agcgcgagca cggccgcgcc gtcgcgcagc gaggagccgt agtcggagcg
  1133701 ggcgaggctg acatggacga ggccgctcga catattggcg gcgaccgcga agatctcctg
  1133761 cgaacgctgg gcatcgccat aaagagccag ggccgcagcg atgtgagcct tggcgagcgg
  1133821 ggtcgggaaa tcgccgagca tcgtgttcgc gtaatagcgc agatcgctga tggcggcctt
  1133881 tcggttgcgc gcaagaacat agagcgcata ggcgatctca ttgccgcgat ccctgacgtt
  1133941 cgtctcgtag ctcagcgcgt tttgcaggtt ttcgagtgcc tgcaccatcg cctgctcggg
  1134001 aacgtcgaac ttctgttcgc gcgcgcgggt gaggaaatcg gtgacatagg cgtcgagcca
  1134061 gagatcgccg gagccggggc tccaaaggcc gaaactgccg gcggaggact gataggcgag
  1134121 cacccggtag atcgcctcct gcacgcgctt cttcacgccc tcatcgtcgg caagtccggc
  1134181 ttgcccggca agctcgccga gatagaggag cggcaaagcg cggctcgtcg tctgctcggc
  1134241 gcagccatag ggatagcggt cgagcgtcat cagcaatgcc gggatatcga aggcggccga
  1134301 acgcgttaca tttatgctga ccgaggcgcc ctgcagcagg ctgtcggcga gcagttgctc
  1134361 gtcgaccgtc aggctgctgc cagcggcgac attgacgacc tgacgctgtg tgaccggcag
  1134421 ggctgccgga cggaccggaa tattcagcgt ctgctccagc gacaggcctg catcattcga
  1134481 gagcgtcacc gtgacgagac cgtcacccgg ataccgtccg gcgagcggta atgtcagcat
  1134541 cgatttgctg ccggcatcga ggttcagcgt ttcggccgct atttgttcga ccgtcaccgc
  1134601 gccgttggtc gtgacctgca actggtaatc gccggcggga ccgtcggtgt tggccacttc
  1134661 aaggcgcaat tcggcccggt ccccgggtgt caggaacttc ggcaggctcg atgtgacgac
  1134721 gaccggatcg cgtatgacga cgtccttgac ggcgtggccg acaccggact tcgtccaggc
  1134781 gaccgccatg atgcgtgccg ttccgttgaa ctgcggaatg tcgaaacgca tgtttgccat
  1134841 gccttcggcg tcgagcttga tggggccaga gaagaaggcg acaagctttt cggtcggggg
  1134901 gctgccctgg agcggcattt ggccgccatc gccgcctgtg cgcaggcggc cggtcgcccc
  1134961 gagcgagccg tcgatcaaac gtccgtagag atcgcgaatc tccaggccga gccgcctttg
  1135021 tccgaaatac cagccatctg gatccggcgc ctcgtaccgt gtcagattca ggatgccgac
  1135081 gtctaccgcg gcgacggtga cataggcgtc ttcgttcgca ccggcgcctc gcacctgaag
  1135141 gccgatgtcg agcggctggc gcggaacggt cttctcaggt gcatcgaggc tgacggcgag
  1135201 ccttcggtcc gccgggtcga cagcggccca tttgacgccg atcgaccgca tcggcatgcg
  1135261 gctctcctgg gcatcgcccg ggcggtagag cgtcgctgtg acataggcgc ccgcgcccca
  1135321 atcggtggtt accggcagtt ccacttcgcc gccggtctcg gaaacggtcg cggtctttgt
  1135381 cgtcaccagg ttttcggtgc cgacagtcac gaggagttcg ccggcaaagc gcggcgacac
  1135441 tctgagcttc gccgtttcgc cgaccgcata ggcctgcttg tcgagagcga tttccagccc
  1135501 gtccggtgtc tccgtcgacg tggcctcgac ataccagccg gcatcgaact caacgctcga
  1135561 ggccgggccg tcgggggtcg ttgcctcgat ctccaaccgg tagcgacccc agccgacggg
  1135621 cacggaaatc acggcgccgt cctccgttac gtcgactgaa ccgcttgcta cctgcttcgt
  1135681 ggagatgacc ggctcgtatt tccaggcggt cccgtcgcgg taccactgat agttccgttc
  1135741 gacgctgatg agcttccagg gaagagccgg catggcggcc ttccggccgt ccgcgtccac
  1135801 ggcgatgaca tggaatttgc cgacggagtt ttccgcgaga tctccggaga attccggctt
  1135861 gatgccgatc atcggcccct cgggtttgac cggcagggtc aaaatgcgtt cgaccgcgcg
  1135921 accgccggcc tcgcgcatgc gaagcgtcac atcggccttg agcagttgcg tcgtcgcggg
  1135981 aacctcggcc agatcgacat tgaagaccga cctgccggtt tcatcgagcg gttcgagggc
  1136041 ctccagaggc agccgcgtat cctcgcttgc ttcttcgtcc gcgaggccga agaaatagcc
  1136101 cttaaacgcc tcatcctgcc gcgttggctt cacggtgatc tcgccttcca gcgcaaggcc
  1136161 tgcggccggc gcgccgtaga ggtagcgacc gtctaccgaa acttcgaccg gcgttccgag
  1136221 ttcgatcgcc gttgcatcgc tcgtcaggtc gaactcggtg cggtcaggca cgaagtcgtc
  1136281 tacgaggaac tgcttttcag cgatcgccga acttttcgga tcggtgaaga tctgcatcgt
  1136341 ccaggtgcca cgcatggcgt tcgccgggac cggcagatcg agtgtgtggc cgccgagctt
  1136401 gccgccgtcg ctgacgagac ggcggtcttc aacgccgtcg ggggcgcagg aaaacgaaag
  1136461 taagcggcag tttctcgatc gcagcgccgt tgacgtcgcg ggcgagtgcc gcggcatgca
  1136521 ccgtttcgcc ggcgcgatag atgccccgtt cggtccaggc gaagacatcg attgcacccg
  1136581 gtgctgcccg cccggtgacg ccgcggtcgg aaaggtcgaa gccggcacgc gtcatgtcga
  1136641 ggaagacata atcgtcgcca cctttccggg cggtaatcac cgccggcgtc atgctcgcgg
  1136701 tgccgcggat cagccctgct gagaaggttg cgcgtccgtc cgcatcggtg gtcgcgctcc
  1136761 cgaggacttc gttgttcttg gcgaccagct gaagttcgac ctctgcgaga ggtttggcgc
  1136821 tggcgagcga acgggcgaat acggtaagcc cgtcggtgcc ggcaaaggtc gacatgccga
  1136881 tatcggacac gacgaaccat tgcgtcgcgc gcgtatccca gtcctgggtg aggccggttg
  1136941 cggagcttgc agtcagcacg tagatgccgg gtttgcgttg cggcagcgcc tcgtcgaccg
  1137001 ggaaactcgt caccacttcc ttgttgagct cggtcttgat gtcgacgctg ccctgccaga
  1137061 cgagttcgcc gctctcgtcc ttgatgcgct cctcactgta gccgtcgatc tgggtcagga
  1137121 actgagaact ggtgagcaga gaggttatgt tgcggtcgcc aatacggtag agcctgagct
  1137181 tgacgttttc ggtgttgacc gagacgatgg gaatgccgcg ccgtgccgtc gagggcagga
  1137241 cgaaactgtc gccggtgaag cgtaccaccg gcattcggtc cttcacatag acttcgaggc
  1137301 tgacgggggt ttccaggact tcctcgacgg aggagggcag accttgcctc aatacgagtt
  1137361 tgtaacgctg cccgtgcgac agcccttcga tgcagatttc gctttccttt gcctccaacg
  1137421 cctgcggagc cgcgccgttg agcgtcacga atgaggaata gtcaggacca ttcttgagaa
  1137481 gcggctcgga gaattgcacg caggcacggg gactggcgcc gtctgcatcc accgtatggc
  1137541 cggtcacgcg gaagccttgc cgcgccctga gatcgagata ggcagtttcg accgtctttg
  1137601 cctgcacgag ttcgaggctt gccttgtagg cctggagcgc cgcgcggtaa ttctgcagcc
  1137661 tgtcaagcgc gaaagccaga gtggcgagcg cattcgcgcg cacttctgcc gtccgtgtca
  1137721 gctggtagcc gttgagtgcc gcgagtgccg cctcgctcgc cacgtccgtg ccggtgaatt
  1137781 ggtttgcggc ctgagccgtt tccagccata gcgcaccgtc ctccggtgtt attgcaagcg
  1137841 cgcctcggaa cgccttgagc gcagcgacaa agtttccggc cgtcaactcg ccatgcgcca
  1137901 tctcgatgag cccgtttacc ccgaaaccga gctgatcttc ggtcaaggcg agattggcct
  1137961 tcacatcgcg cgcctgctga aggaggtcat ccgagacgaa gtcaagtgca ggcggcgccc
  1138021 cgatgtcggc ttcgccaccg gcggtttcca cgatttttcc agcgatcgct cccacgaacg
  1138081 tgttcagttg gttgaagtcg gatttgagga agcaccactt cacctttgga ttgtaggtaa
  1138141 aggccctgca ggagcggtca gcgatgcagg cgctctggca ctggtcgagc gagacattct
  1138201 gctcggtgcg cagatcgaag ccgaaatagt cggcatcacc ggaaagttcg actctgcgct
  1138261 cgggctcggc ggcgaaaacc ggcgcgccga gtgaaatgag agtgagaaga atggccgaaa
  1138321 aactgagaaa cgcccgcata gacataagtc cccccgacgc tggccgcttc gattgtaaat
  1138381 tactcttcaa tcatcgccct gcattgtcaa tcgaggaaac ggtacctccg gcacagtctg
  1138441 tggctgcgcg tggcgtgaca ccctcgagcc gagcgtcggt gacccgacgc gtccgcttgc
  1138501 ggacggcttt gaaactgtga taattctcac aaaagcgcat cccgctagag cttgctttcg
  1138561 tacggaatga acatggccag ccgtagggcg tcacgcatcg ccatcttgtc caacgcgctt
  1138621 tcatcgcgca ggaccgtgca tctgaaggag gcggcggcgc tgctcggcgt gtcggaaatg
  1138681 accgtacgcc gcgatgtcgc cgacaacccc gggcttttcg gatacctggg cggtcacatc
  1138741 gtttcagcgg ccgacatcga gagcgatgcg ccctacgagc ttgcccgcgc ggcagacagc
  1138801 catgccgcgg caaagcggga ggcttgcagg catgccgccc ggcacatccg acccgacgag
  1138861 acgatcttca tcgattgcgg caccacgctc gaatatctgg tcgatctgat accggagaat
  1138921 tactcgataa cggcggtatg ttattcgttg aacacagccg aaaggctgac gcggaaggca
  1138981 aatctccgca tcgtgatgct gggaggcgtc taccattcgt catctgcttc cttttccggc
  1139041 gcgcccggtc ttgagacact cgaaaggctc ggcatcaatg tcgcttttct ttcggccgcc
  1139101 gggattgacc cggtgcgggg agcgacctgc gttcatttcc atgaggtgcc ggtcaagcag
  1139161 aaggtgattt cgctggcgcg tgagaactac ctcgttgcgg acaaaagcaa gctgggcaag
  1139221 ctgaaggcgg ccttctttgc tccgctcagt gcctttcggt cgctggtcac ggaagacggt
  1139281 gagacggcgc tcgctgggga ctctgccttg acaggcacct aggaatgatg gaaatctaac
  1139341 agaagttgtt ataaagctaa cattccgtcc gctccaggag ccgcaacaat ggtcggggaa
  1139401 gatcggggag aaatcggttg gaagaccttg ctctgaaaag cacggcggtg caccccgccg
  1139461 gcgccggcga taactggccg cgcaacgacg gtgtcgaact cgacctttcc tgggtcctgg
  1139521 atcagcgcgt caatctttcc gcggccgaac gccgcgttca gacgctgccg ggccggcgca
  1139581 ccgtcaagaa agatgcgcag gccgcctggc tcttgaaagc cgtcacatgc atcgatctga
  1139641 cgacgctcag tggcgacgac acgaccgaac gcgtcaagcg cctgtgcgcc aaggcgcgtc
  1139701 agccggtgcg ccaggacatt ctcgacgcac ttggtatggg cgatcgcggc atcacgaccg
  1139761 gggcgatctg cgtctatcac cgcttcgttt cgactgcggt ggatgccctg gagggctcgg
  1139821 gcattccggt cgcggcagtg tccacaggct ttccggccgg cctcgtgccg catgacgtca
  1139881 agctcaggga aatcgaagct tcggttgccg acggtgcccg ggagatcgac atcgtcatca
  1139941 cgcgcgagca tgttctgacc ggcaactggc aggcgctcta cgacgaaatg cgggattttc
  1140001 gtgcggcctg cggcgacgcc catgtcaagg ccatcctcgc gaccggcgac ctgaagacgc
  1140061 tccgcaacgt cgcgcgcgct tcgcttgtct gtatgatggc gggggccgac tttatcaaga
  1140121 catcgacggg aaaggagggg gtgaacgcga cgctgctcgt caccctcgcc atgctcagga
  1140181 tgatccgggc ctacgaggag cggacaggat tgaaggtcgg ttacaagccg gccggaggaa
  1140241 tctccgccgc caaggacgtg ttgaactacc agttcctcat gagagaggaa ctcgggcgag
  1140301 attggctcga gcccgatctt ttccgcgtcg gggcatcgag cctgctcggc gatatcgagc
  1140361 gccagctcga gcatcacgtg agcggtgcct attcggccct gaacagacac ccgataggat
  1140421 gatgaaatga gcgttgcgac cttcttcgac gatatgtcct acggcgtggc tcccgaagcc
  1140481 gatacggagg cacgcgcctg gctcgaccgg catgaaggca agttcggaca cttcatcaat
  1140541 ggcgcctttg tcgctgcggt ctccgggaag acgttcgaca cgttcgaacc ggcgacgggc
  1140601 gcattgctcg caggaatcgc acgcggcggg cgcgaggacg tcgacgcggc ggtggcggcg
  1140661 gcgcgcaagg cgcagggccc ctgggccaag ctctccggcc atgcccgcgc acggcacctc
  1140721 tatgcgcttg cgaggctgat ccagcgccat gcccgtttga tcgccgtcgt cgaagccctg
  1140781 gacaacggca aaccgatccg ggaaacgaga gacatcgacg tcccgcttgc cgcccggcat
  1140841 ttctatcatc acgccggatg ggcgcagctc caggaaacgg agttcgccga tcaggtgccg
  1140901 gtgggggtcg tcggccaggt catcccgtgg aatttcccgt ttttgatgct cgcctggaaa
  1140961 gtcgcgcctg cactggcact cggcaacaca gtgatcctga agcccgcgga gtatacgcct
  1141021 ctaacggccc tgctctttgc ggagatggcc gccgcgtcgg ggcttccccc gggcgttctc
  1141081 aacgtggtga cgggcgaggg cgagacggga gcactcatcg tagagcatga ggatatcgac
  1141141 aagatcgcct ttaccggatc gaccgagatc gggcgcctca ttcgcgaaaa gactgccggc
  1141201 tctggaaagt cgctgacctt ggagcttggc ggcaaatcgc ccttcatcgt tttcgacgat
  1141261 gccgatatcg acgcagcggt cgaaggcgtc gtggacgcga tctggttcaa tcaggggcag
  1141321 gtctgctgcg ctggttcccg cctcctggtg caggaaggcg tggcaccggt tttccatgaa
  1141381 cgtttgaagc ggcgcatgga cacgcttcgc gtcggacatc ccctggacaa gtcaatcgac
  1141441 atggcggcga tcgtcgcgcc cgttcagttg cagcgtatcg cagagctggt ggcaaagggt
  1141501 gtcgccgaag gtgcgtcgat gcatcagccc aggatcgagt tgccgaaggg cggcagtttc
  1141561 tatcggccga cgctgctgac cggggtccag ccgacttccg tggtcgcgac ggaggagatt
  1141621 ttcggccccg tggccgtgtc catgaccttc cgtacgccgg acgaggcgat tcagcttgcc
  1141681 aaccatagcc gctacggcct cgccgcgagc gtctggagcg aaacgatcgg gcttgccctg
  1141741 catgttgccg ccaagcttgc ggccggcgtc gtatgggtga acgcgaccaa tctcttcgat
  1141801 gcagcggctg gcttcggcgg aaaacgcgaa tcgggcttcg gccgagaggg cggacgcgag
  1141861 ggttgctacg agtatttgaa gccgaaggcg tggatcggca ggaagctgcg cgcagaaccc
  1141921 gccacgccgg ctccgaaaac ggcggcaggc gacttcgtct tgcctgtgct cgatcgcacg
  1141981 gccaagctct tcatcgatgg aaagcaggcg cggccggacg ggaactattc gcggcccgtg
  1142041 ctttcaccca aaggcaaggt ggtcggcgag gtcggcgagg gcaaccgcaa ggatatacgc
  1142101 aacgccgtcg ttgcggcccg gggtgcctcg ggctggtctt ccgcaaccgc gcataaccgc
  1142161 gctcaaatcc tctattacat cgccgaaaat ctgagcagcc gcggggcgga attcgccgat
  1142221 cgcatcgccg caatgacggg ggcgtcggcc gccagtgccc gaacggaggt cgaggcttcg
  1142281 attgcccggc tcttcagcta cggcgcctgg gcggacaaat acgaaggcgt cgtgcatcag
  1142341 ccgcccctgc gcggggtcgc tctggccatg ccggagccgc agggcgttgt cggcgtcatc
  1142401 tgcccgccgg aagcgccgct gctcgggctc gtcagtctcg tggctccgct gatcgccgtc
  1142461 ggaaaccggg tgatcgcggt gccgagcgaa acgcatcccc tggccgcgac cgacttttat
  1142521 tccgtcctcg agacctcaga cgtgccgccc ggcgtaatca acatcgtcac cggtttggcg
  1142581 accgagctcg ccaaggcgct cgccgcgcac aacgatgttg acgcgctctg ggccttcggt
  1142641 tcgccggagc tttcgacgct ggtcgagagg ttgtccatag gcaatctcaa gcgtaccttc
  1142701 gtcgattacg gccggtcgat cgactggatg gatcgctctg cggcggaagg acaggtattc
  1142761 ctgcggcgcg ccgtcgacgt caagaacatc tggattcctt acggcgaata gactcccgct
  1142821 tttcccaagc ggtggtcttc ccctcggaag cgtggagaaa gggcaactgg ctgttgacgg
  1142881 ggcgcgccgg aaacggcctg atgccatcgc gccgcttatc atttcagctt ccctgatgcg
  1142941 acggtagcgt gatgatcagc ggcgggcttc tttctccatt attcctgctc gtttaggaat
  1143001 gtggtcggag ggtgcgcaaa agtcgcggtg gtactttgat ttgctgcgcg tttcccggcc
  1143061 ggttatgtcc cggagaacgc agtggaggag aacaggatgc tcaagaatat cgacccggct
  1143121 ctgaatgccg atgtgctgca tgcgttgcgc tctatggggc atggtgacac gcttgtgatt
  1143181 tccgatacca atttcccgtc ggatgccatc gcacgacaga ccacgctcgg caaattgctg
  1143241 catatcgaca atgtttcggc ggcgcgcgcg gcgaaggcta tcctttcggt gcttcccctc
  1143301 gatacgccgc tgcagccttc ggccgggcgc atggaggtca tgggcgcacc cgacgaggtc
  1143361 ccgggcgtgc aacgcgaggt gcaggccgaa atcgatcgcg ccgaggggaa gcccgcgccg
  1143421 atgtacggca tcgagcgttt tgccttctat gaggaagcga agaaggccta ttgcgtcatc
  1143481 accaccggcg agacacggtt ttacggctgc tttcttttta ccaaaggcgt cgttccgcca
  1143541 gaaaccatct gaaagagggc acgccgatgg ccgagctcaa agtgaggact cgggagacgg
  1143601 gggcgagcgc cgttgtcgga cgaaccggtt tgccgcatgt taagtcgctt accggcggcg
  1143661 agctcgatat cgtcacaaat ccttcgcagc cgggattcgg gccgctcgat cttctctatg
  1143721 catcgctcgc gagctgcctg gtgctcagcg cccgcatcgc ggcgagccgt ttcggtgtgc
  1143781 tcgaccgtct caccgaggtt tccgtcaagg tcaccggcga gaaggcccat gacgaacctt
  1143841 ctcgcgtcgc gcggttcgat atcgccttca tcatcaaggg ggatttcgac gagacggtcc
  1143901 gccacgccat tgccgaggcg gccgaggagg agatctgcac cgtcagcaac acgttgcgcg
  1143961 gcgggccgga tttcgtaagc acggtgtcgg ctgaatagaa aattaaacaa agggagaaga
  1144021 gtccgcaatg acgcgtccgg cttatcaatt caattcaatc atcgcgcgct cgccatcgcg
  1144081 atcggtcgtc aacggtttgc gcgccgaaga tcgcggcaac cccacctatg agggggtcaa
  1144141 gtctgagcac gacgcctatg tcgaggcaat gcgcgatgcc ggcgtccttg tcaccctgct
  1144201 gccggcgctc gaagccttcc cggactcggt tttcgtagag gatcccgctc tcgttttcac
  1144261 ggaaggggcg atcctgcttc gaccgggtgc ggccacacgc gccaaggagg tcgaggaaat
  1144321 ctccccgacg ctgcacgaca tgttcgatgc ggtgctcgac ctgcccgagg gctatgccga
  1144381 tggcggcgat gtgctgacga ctcgggaaag cgtcatgatc ggcctttctg caagaaccga
  1144441 taaggagggc gcagcggcgc tgcgggcgtg cctcgaaaaa ctggggcgcg cgagcgagat
  1144501 cgttgcgaca cctgaaggcg tcctgcactt caagaccgat tgctcgctgc tcgacgatga
  1144561 aacggtgctg tccaccgatc gtcttgcgcg ttcgggcgtc ttcgggaagt tccggcagat
  1144621 gatcatccct gagggcgaag aaccggccgc caacgctctg cgggtcaacg acgtggttat
  1144681 ggtcggctcc gatttcccga ggaccatcga gatgctcgac aaggccggct acatggtcgt
  1144741 accgctgaaa acgacggaaa tcggcaagat cgacgcgggg ctttcctgca tgtcgctgcg
  1144801 gtggttcagc gacaggatgt gatcgatcgc gcggcgccgt ctctcggatc tgcccctctc
  1144861 ctcggttagc cctctcccgt ttgcggggaa aaggtgcccg caggcgaatg acgggcgcgc
  1144921 tttcagtccg ccggcgaaag atccccgaaa accgtcggga tgagttccga tacggtcggg
  1144981 tgtatgtgca cggcgcggct gatcgtcgta tatggcctct tcgcatacat cacgtcgagg
  1145041 atgctctgta tcgcttcgtc cccacccgtc ccgagaatcg aggcacccag aatatccttg
  1145101 gtgtccgcat cgacgatcac tttcatgaag ccctgcgttt cgcccttttc gaccgcgcgg
  1145161 ccgacccggg tcatcggccg ggtcccgata aggagcttgc atcctttttt gcgcgcttcg
  1145221 gtttccgtca taccggcgcg acccagcggt gggtcgatat acagtgcata ggtctggatg
  1145281 cggtcgctca cgcggcgcgg atcgtcatcg aggagattgg cggcgacgat ctcgaaatcg
  1145341 ttgtaggacg tgtgcgtaaa tgcgcctcgg ccattgcaat cgcccatcgc gaaaatgtgc
  1145401 ggaatattcg tgcgcaggct gtcgtcgacc tcgatatagc cccgtgcatc ggtttttaca
  1145461 ccagcctttt ccaagcccag gtcatccgta ttcgggtggc ggccggtcgc aagcagcaca
  1145521 tgggaaccgg tcacctccgg ctcgcccgag gtgcaatcga cgccgacggc gatgccggcc
  1145581 gctgtttgcg agaagcggat gcattccgca ttcgtgcgta tccgaatgcc ttcgttctcg
  1145641 aggatctcgc ggattgcatc ggaaacttcc ggatcctccc gcccgatcag acgcggcccc
  1145701 ttctctataa cggtaacatc ggagccgaag cggcggaaca tctgggcgaa ttcgagcccg
  1145761 atatagctgc ctcccacgat gacgagatgt tccggcagtt cggcgaggtc catgatggag
  1145821 ctgttggtca gatagggaat gccgttaacg ccgggcagag ccggaacggc ggcgcggccg
  1145881 cccacattga taaagatctg ctctcccgaa atcagctcct cgccgatgcg gatctcccgc
  1145941 ggaccgccga aacgggcgtg gccctcgaag agggtgcagt tcgtcatacc cctgagccat
  1146001 ttttgcaggc cggaacgggc atcgagccgc accttttcct ttcgcgccat gacgcggccg
  1146061 aaatcgaccg aaacgggccc tgtcgtcatc ccgtattcgg caccgcggcg ggccgtatgg
  1146121 atcgcatagg cgcttgcgac catggctttt gtcggcatgc agcccgtatt gacgcaggtg
  1146181 cctccgaaga gcttgcgctc gatgagcgcg acagtcttgc cggcgtcggt caaccgtccg
  1146241 gcgagggacg gccccgcctg gccggcacct atgatgattg catcgaagtg cttgttcatg
  1146301 acaacccccg aggagatgct ggcgccgggc ggaagagtgg tccacattaa gcttgattgc
  1146361 aatgtgcaac tcgacgaggc gcccggtcag agcgggacgg cggctggtgc ggatatcaac
  1146421 tgcagggaca tccggctcta tttttcgccg aaagcttaca tatatgaaat gacttggccg
  1146481 gacgcggcgg agaatctgtg atcaattttc gaggttgaaa ccgagaggga gacaatcatg
  1146541 agactgaact ttaccaggac actgatcggc accgccttcg tgcttgcgct tgccaccgcg
  1146601 ccggcagaag ccgacgtcgt cgtctcctcg aagattgata cggagggcgg cgttcttggc
  1146661 aacatcattc tctccatcct gaacgccaac gacatcaaga cgacggaccg cgtgcagctc
  1146721 ggcgccacac ctgtcgttcg aaaggcgatc atcgccggcg agatcgatat ctatccggaa
  1146781 tataccggca acgccgcctt cttcttcgag aaggccgagg atccggcctg gaaggatgcg
  1146841 gccaaagcct atgaagaggc aaagaagctc gactacgaag ccaacaagat cgtctggctg
  1146901 acgccgtcgc cggccaataa cacctgggct atcgcgctgc gcaaggacgt tgccgaaaag
  1146961 aataatctca agacgctctc ggatttcggc aaatatgttt ccggcggtgg cgaggtcgtg
  1147021 cttgcggcgt cgtccgaatt cgtcaactca gctgccgcct taccggcctt ccagacaacc
  1147081 tattccttca agctgaaacc ggaacagctg atcacgctct ccggcggcga caccgccgcg
  1147141 acgatcgcgg ctgcggcaaa ccagacgaac ggcgccaatg ctgcaatggt ctacggcacg
  1147201 gacggcggaa tcgctccctc tggccttgtc gtcctcgagg atgacaaggg cgtgcagccg
  1147261 gtctatcagc ctgcgccggt cattcgcgag gcggttctga aggaaaatcc ggcaatcgaa
  1147321 gaactgctga aacccgtctt cgaaaagctc gacctgacga ccctgcagga gctcaacggc
  1147381 cgcgtgcagg tcggcggcga gtcggcgaaa gccgttgcgg aggatttcct gaaggcaaac
  1147441 ggcttcctga aatagcttga cgtgagggaa gggcgctggt cggataaggc tccgaccgcg
  1147501 cttttttcat cttgcgtcga acggacggcc gaatggcgat tggtataatc caggaaaaag
  1147561 aacgcttggc attccgtttc gacaaactcg gggtcatcat ctcgatactc gccctttatg
  1147621 gcgcgctcct tgcccctttc gcgacatatc gcgcaaacag aatcattcag ggcgaagcgc
  1147681 ggggtataat ggaagctctt cctccacacc tcggctacgg gctcctcttc ctcgtggtcg
  1147741 ccggcgctgc agtcgcgctt ctgaggacgc cggccctttt ccggatggcc atggcgctcg
  1147801 ctgcactggc ggctctcgcc ggtctgatcg gaattgcggc agatcatctg acgccgccgg
  1147861 agaatagcta tgcacgggtg tcccccgcat ccggcttctg ggttctggtt ttcgcattct
  1147921 cgctgctgct caccgatgcc ctgactcgcc ttaatccagg acccggtctg cgccttctcg
  1147981 tactggcggg cgttctcgtt cttgcagggt caatgctcgt cgccggccgc tgggacgggc
  1148041 tttcgatcat gaaggaatat gccaatcggg ccgatttgtt ctgggccgag gctggccgcc
  1148101 acgtgacgct ggcgctcggc tcgctggccg ccgccaccgt cgtcggtttg cctctaggca
  1148161 ttctgtgcca ccgggtcgaa cggctgcggg cgggcgtgct caacgtcctg aacgccatcc
  1148221 agacgatccc atccattgcg ctttttggta ttttgatcgc gccgctcggc tggatcgccg
  1148281 caaatattcc cggcgcttcg gcggtcggca ttcgcggcat cggtgcggcc cccgccttcg
  1148341 tcgcactttt cctctattct ctgcttccgg tcgttgccaa cacagtggtg gggctcgcgg
  1148401 gtgtgccgcg cgcagccaac gacgcggccc gaggtatcgg catgacggat cggcagcgcc
  1148461 ttgttacgat cgagttcccg ttggcctttc cggtcatcct gaccggcatt cgtatcgtgc
  1148521 tcgtgcagaa tatcgggctc gccacgatcg ccgctcttat cggcggaggc ggcttcggcg
  1148581 tcttcgtctt ccaaggggtc ggtcagacgg cgatggatct ggtgctgctg ggcgccatcc
  1148641 cgacggtcgt gctggccttc accgcggcga tcgtactgga cgcattgatc gaaatgaccg
  1148701 tgccaaatag cagtcagggc aatgccgcat gatccaaata gaagaagtta ccaagcgcta
  1148761 tggcgatacg acggtcgtga acggtgtcac gctgacggtc gcaccgcata cggtcaccgt
  1148821 tatcgtcggc acctccggct caggcaagac gacgctcctc agaatgatca accgcctcgt
  1148881 cgaaccgacg gcggggatcg tcaagatcga cggcgaggac aatcggtcga tcccgggtta
  1148941 cgaattgcgg cggcgcatcg gctacgccat tcagggccac ggtcttttcc cgcatcgcac
  1149001 ggtcgctcag aacatcgcga ccgtgccgac attgctcggc tgggagaagg acaggaccga
  1149061 agccaaggtc gaagaattgc tgaagctctt ccagctcgat ccggcggact tcgggccgcg
  1149121 ctaccctcac gagctttccg gcggacagca gcagcgggtg ggcgttgcga gagcgcttgc
  1149181 ggcggagcca aacgtgcttc tgatggacga acccttcggt gcgcttgatc cgatcatccg
  1149241 ctccaaggct caggaagacc tggccgccat tcagaagcac ttcggaacca cgatcatcct
  1149301 cgttacgcat gacatggaag aggctttcca tctcgccgac aagatcgcgg tgatggacaa
  1149361 gggcgaggtg gtgcaatatg cgacccccgc cgaaatgctt gtcaagcccg ccacgccctt
  1149421 cgtcgagacc ctggttggcg ccagcgagcg tccgtttcgg ctgctcggca tcgaaacggt
  1149481 cggcgaggcg gtcgagcccg gttcggcgga gggccggccc gttccggagg tcctcagcca
  1149541 gcgcgatgcg ctgtcggaac ttctgtggtc gggccgctcg gcgctgccgg tcgcggcggc
  1149601 gaacggcgag attctcggca gggttactct ccaagccatc gtgaagcgtg cggcgaggcc
  1149661 gcgatgatgt tcaccttacc caatctcttt cggttggcgg tacttgttgt cttgctggcg
  1149721 ttcctcctgc aacccgcatg gttcgaggcg atgttgacgc ccctggttca ggagaacgcg
  1149781 ccggccatct acaaccaggg cagtcttttc tggctgacgg ttctgcattt gaggacggtc
  1149841 ttcatcgcga cgtttgccgc caccgtcgtc gccgtttctc tggcgatcat cgttacgcgg
  1149901 aaagcgggcg ccgaatttct gccgctctcg cgcagccttg tgaatatcgg gcagactttc
  1149961 ccgccggtgg cggtacttgc gcttgcggtg ccaatctatg ggttcggcga aaagccgacc
  1150021 ctcatcgccc ttttcctcta cgggcttctg ccaatcttcg aaaacgccct gacaggcctg
  1150081 acgacgttgc cgccgaccgt agtggaagct gcacgcggcg cgggaatgac cggaagccag
  1150141 cggcttatca ggatcgagct tcccctggct ctgccggtga tcctgacggg tgtccgcctt
  1150201 tccgtcgtga tcagtcttgc gacggcaacc atcgggtcga ctgttgcagc aaagacgctt
  1150261 ggcgaagtca tcatcgccgg acttcagtcg aataatctcg cctttgtcct ccagggcggc
  1150321 ctcatcgtcg ccgcgctggc tgtcctcatt cacgacgcat tacaaggtct ggagcggaca
  1150381 cttgccggga gggttcacgt ctaaattgcg ggcgacacac ttgcagctat gaaaatgaat
  1150441 ttcaacaaat agtgtatttc ccgctttttt gttgacgcat agaaatttct atctcagtct
  1150501 acgaaaaata attacgtcga ccgagggaac agcgtgagca tgaaagtcgg gataatcgga
  1150561 ctcggattcc gtctggggta cctgggctac gtcttcaagg cgatcgatga agccttcgag
  1150621 atcgcgggat atgtcgatcc ggagccggcc ggtctggcca cgctgaccga gaagggcatt
  1150681 tccgcgggca aggcgtacgc cacgcccgaa gagctgatcg ccggagagac gctcgacctc
  1150741 ctcatgatcg gctcgccgaa ccatctgcat ctcgaccata tccgcattgg cctcgaagcg
  1150801 ggcctcaagg ttttctgtga aaagcctctt gtcagcacca tcgagcaaag cctggaactt
  1150861 gcggccctgc tttcgaaaca cggacctgac cggctgatgg tcggcctcgt gctgcgctat
  1150921 gcgccgctct atcgcgacct gcgcgccgcg caagccgcgg gaacgctcgg acacgtggtt
  1150981 tcgatcgaag ccgccgagca catcgaaccc tatcacggcg ccttcttcat gcgcgactgg
  1151041 cgccgatacg gacgctatgc cggcagcttc atgctcgaga aatgctgcca cgacctcgat
  1151101 ctctacaatg gcgtggtcgg agcgcgcccc gaacgtgtcg ccagttttgg tggccgcaag
  1151161 agtttcattc ccgccaatga cccgacccgc gacggcataa acgacctcca gcttttccac
  1151221 cgcaagccga gtggctggcg cggttccgac agggtcttcg acagcgacgg cgatatcatc
  1151281 gactaccagg tcgccattat tgagtatgcc aatggcgtcg caatgaattt ccacaccaac
  1151341 ctcaacgtgc cggaccagtt ccgtcgcttt tgcgtcatgg gatcgcgcgg tatggcggag
  1151401 ggcgatttca tcaggggtta tctcgacgtg cacgaggtgc tctcgggcaa gaaggtcgtg
  1151461 gagaagcaat acgcaaagga aacggcgctt tcgcaacact acggcgccga cgaacagatg
  1151521 gcggccgaga tcatagcgca tgtcagggac ggcgggccgc tgccggtctc gccgctcgat
  1151581 gcgctggaag caggcattct ggcactctcc atggacgagg cgcggatgaa gaggaccgtg
  1151641 gtcgatctcc gacccctttg ggaccgcttc gacgaagccc tgcacgaccg tgcagcctga
  1151701 gagggcgagg gtatgagcgt tcggcgcagc acgatcattt tcgcctggat cctgcttctt
  1151761 cctgccgctc tctacgtgac ggtgatcgtc gcctatccat tggtcgacac cttcatcctg
  1151821 tctttcacgg acgcctcgct gaagaagacg acaaattggg tcggcacggc caattacaat
  1151881 aagattttca acggcacttt tgcggaagtt atccttcgca ccttcgtctg gaccgccttt
  1151941 tcagtggcga taaagatgct cataggcacg ttcggcgcgg tgatgctgaa cgccgcagtg
  1152001 ccggggcggg ccctgttccg cgtgctcacc atgcctcctt ggatcgtgcc gatggcgatc
  1152061 ggcatcttca tgtggggctg gatgtataac ggccagttcg ggatgatttc cgggctgctc
  1152121 cagaattggg ggctggtgga cggcccggtc gcttttctgg cgcatggttc caccgctttc
  1152181 tgggcaacca ttatcactga tgtctggatc ggcgtgccgc tggtgacgct ctacctgctc
  1152241 gcctccatgc aagccattcc gcaggatctc tacgaggctg cctggaccga cggagcaggg
  1152301 cgcttttacc gcttccgccg catcaccctg ccgctcctgg tgccgtcgat gataaccatg
  1152361 tcgatgctgt cgctgatcgc cactttcaac tcgttcgaca tcatctggat cctgacccag
  1152421 ggcggaccga acggcgacac gacgacgatg atcatcgata cctaccgcac cgcgatcggc
  1152481 tcaaagaagt atggggaagg ggcggcgcgc gccgtgctga tctgcatctt tctgtcgatt
  1152541 ttctgtgtcg cctatttccg cgtcacgcat cgccttgcct cgggagaaag ccgatgagcc
  1152601 agccctctat gatcaaccgc tatcgctggt acgaactcct tgccatctac gcgggtatct
  1152661 tcgtcttctt aagcttcatc ctcgcaccct tcgtcgaagg ctttcttgtt tcgctgaagc
  1152721 cgcttgggcg ccttttttcc tctccctatc gcttctggcc ggaaaacggt tccttcgagg
  1152781 cctatcgcac gatgtgggtg agcgttccgg gcttcgcccg ctatatcttc aactccttct
  1152841 ttatttccat catcgtaaca gccgtcgtgc tggcgctggt ggtgccggcc gcctacgctc
  1152901 ttgcgcgctt caaattccgt ggcagcgggg cgttgcttgc cgcgttcctc gcggtcaaca
  1152961 tgttctcggg cgccgtgctg ctcatcccgc tcttccggtt gatgcgcagc ttcggcgtgc
  1153021 tgaacaccta cttcgccatg atcgtgcctg gtgtcgcctt cctgataccc tcggccatct
  1153081 ggcttctgcg cacctacatg atgcgcatac cgcgcgagtt ggacgaagca gccttcgtcg
  1153141 atggtgcaag ccgcttctac acgctgcgcc gcgtgatcct gcccatcgcc atgccgggca
  1153201 tcacagtcgt ggcgattacc accttcatcg gctcctatgc ccagcagttc atcttcgcgc
  1153261 tgaccttcaa ctccaagacc gagtacatgc cgttgcccgt gggccttttc gcctatttcg
  1153321 gccgccagga agtggtctgg aacgagctga tggcagccag tttcgtcggc atcgcacccg
  1153381 ccgtgatcgt gatcttcttc ctgcagcgct atctcgtcag cgggctgacc gccggcgcgg
  1153441 tgaaacaata agcaaccacc aaaatagggg agtctaatca gtgacaatcg cttacaaagc
  1153501 tacctgtttc acgcttgcct tgctcggatc gaccgccctc ggcggctttg ccgcacaggc
  1153561 tgccgatcag gagatcagct ggatctattg cggcgacaag attgatccga tccacgagaa
  1153621 atacatcaag gaatgggagg gcaagaatcc cggttggaag gtcacgcctg aagtcgtcgg
  1153681 ttgggcccag tgccaggaca aggcgacgac gctcgccgtg gccggcacgc cggtcggcat
  1153741 ggcctatgtg ggttcccgca ccctcaagga attcgccgag aacgagctga tcatcccggt
  1153801 tccaatgacc gaggaagaga aaaagagcta ttacccgaac atcgtcgaga cggtgacctt
  1153861 caacgacaat cagtggggcg tgccgatcgc cttttcgacc aaggcgctct actggaacaa
  1153921 ggacctattc aagcaggcgg gcctcgaccc ggagacgccg ccgaagagct gggccgaaga
  1153981 gatcgccttt gcgaagcaaa tcaaggaaaa gaccggaatt gcaggttacg gccttcccgc
  1154041 caagacattc gacaacacga tgcatcaatt catgcattgg gtttacacca ataacggcaa
  1154101 ggttatcgat ggcgacgaga tcgtcatgga cagcccggaa gtgctcgcgg cgctgcaggc
  1154161 ctacaaggac cttgtgccct attctgtcga aggggcgacg gcctacgagc agaacgagat
  1154221 tcgcgccatt ttcctcgacg gcaaggtggg catgatccag tccggctcag gcgccgccgc
  1154281 attgctgaag gataccaaga tcaactgggg catcgcgccg ctgccgctcg gcccttcggc
  1154341 caagggcgaa ggcacgctcc tcatcaccga cagcctggcg atcttccagg gcacgggcgt
  1154401 cgaggaaaag gcgatcgagt ttgccaagtt catcacatct cccggtccgc agggcgagta
  1154461 tgaactgcag ggaggcgcag ggctgacacc gctgcgcccg tcgccgatgg tcgatgagtt
  1154521 cgtaaaggcc gacccgtcgt ggaagccatt catcgacggg atcgcctatg gaggtccgga
  1154581 gccgctcttc aaggactaca agggcttcca gaacgctatc atcgacatgg tccagtcggt
  1154641 cgtgaccggc aagtccgagc cggtggacgc tttgaagaag gcggcagctg acatcgaaca
  1154701 gtataagtaa atcccaccgg gaccgctggg cctcggctcg gcggtcctcc ttcatgttgg
  1154761 cggaatgccg ctgcgccggt ggccggagac agatattggg acagctcact ctcaacaagg
  1154821 ttcagaaatc ctacggcacc tacgaggtgt tgaagagcat cgagctcgaa gtcggaaatg
  1154881 gcgaattcgt ggtcttcgtc ggaccttccg gctgcggcaa atcaacactg ctcaggatga
  1154941 tcgcggggct tgacgagacg accgcgggtg acatcgtcat cgatggcaag cgtgttaacg
  1155001 atctgccgcc cgtcaggcgc ggcatagcca tggtcttcca gtcctatgct ctatacccgc
  1155061 atatgagcgt gttcgagaac atcgcctttc ctctacgggt cgagaagatg cccgaggaga
  1155121 aactgaaggc gaaggttcag catgccgccc gcatattgca cctcgatcag cggctcgagc
  1155181 agaagccggg catgctgtcg ggcgggcagc gtcaacgtgt ggcgatcggc cgggcaatcg
  1155241 tgcgcgaacc gaagatcttc ctgttcgacg agccgctgtc taacctcgat gctgccttgc
  1155301 gcgccgatat gcgcattgag ctcgcgaagc tgcacaggca tttgaaggcg acgatgatct
  1155361 acgtcacgca cgaccaggtc gaggcgatga cgatggcgga ccggattgtc gtgctgaacg
  1155421 ccggagagat tgcgcagacg ggagcgccgc tcgagcttta tcacaaaccc gcaaacatat
  1155481 tcgtcgcagg atttatcgga aaccccaaga tgaactttct gccggtcacc tgtacaggtg
  1155541 taaacgatgc cggtgtggaa gtggactaca agggacagac gattctcgtt ccggtcgtac
  1155601 cgcgcgcggg catgaccggg cgaaccctga cgctcggggt gcggccggaa catatccgga
  1155661 tgggcgacgc cgacctgacg ctgacggtga ccccctcggt catcgagcgt ctcggcgccc
  1155721 atacagtggc ctatgtggcg cttgacgggg aaggggagaa ctattgcgcc atgctgccgg
  1155781 ggacactcgc gatccgcgcc gaccaacggg tcaagaccgg catcggtgcc atcgactgcc
  1155841 acctcttcga cgaaaagggg atggccttcg agcggcgggt agagatgacc gacatcgata
  1155901 tgtcgcactt cgatccggcg gcggcttgat catgggcgtg acgatcaggc tgctcaacag
  1155961 cgatgatgtc gaaaccttcc gcagcattcg gatcgaggcg ctgcaggcgg agcccgcatc
  1156021 ttttgccagc agcgctgaag actgggagag actctcaggc gacgaatggc ggcgcagaac
  1156081 cgtcgacaac cccgtcttcg tcgctttcca ggatgacgtt cccgtcggga tcgccggcct
  1156141 catacgtcag agcgccagca agatggcgca ccgcgcaacg ctggtcatgg tctatgttcg
  1156201 gcgggaactg cgaggcacgg gcgtcgcgaa acggctgctg aatacagttg cggatcacgc
  1156261 gcgggaaatt gggatcaggc agatggagct tgccgtcagc gccgacaatc cggcggcgat
  1156321 ccggttttac aatcgcgagg gtttcgccga agttggacgc attccgggcg gattgcttca
  1156381 cgagggccgg gaaatcgacg acgtcataaa ggtgagacgc attgccgatt gagcgccggc
  1156441 ccatcctgca ggcgacccct ccgccgccgc atgttgcggc agaagcgggg gtagcggaaa
  1156501 gcagtccgga aaggcattga cgtctcgaac aatcgcgcga aaatcggtgg cttaccggac
  1156561 tgctttggtt cactcggcgc gggaggcagg aatgccggaa acaaccgtca acgtgcgtta
  1156621 catggtggac gacgtccagg ccgccgtagc gtggtacacg aaacatctcg gattctcggt
  1156681 tctctccaat cacgcccccg ctttcgcgga tgtccgtcgg ggagcgctac ggctgctgct
  1156741 gagcggcccc ttgagctctg cgggacggcc gatgcccgac ggcgaacgtc cttcgccggg
  1156801 cggctggaac cggatccacc ttgtggtgga tgatctggct gccgaggtcg agcgactgcg
  1156861 tgccgccggc gtggatttcc gcaatgatgt cgtaaccgga cccggcggct cacagatatt
  1156921 gctgaaagac cctgctggca acttcgtgga actgtttcag ccggcggctc gctgaccgca
  1156981 cacacacttt tcccgctcat gaatttcaca caccttggtc tggtccatga ggatcggcga
  1157041 tcattggcca gatgtcgcgc cttgcgcgcc ggtagggcgt tttcgccgga tcgttggggt
  1157101 agggcgtacc ggcagagcag tagaggattt cagaggcgat cttcgagaaa gacgcgtaga
  1157161 aatggttcgt ggatttgatc acgaggatct tcttcgagcc aggatcgatg tccatagcgg
  1157221 agaaaagact cgggtcgaag ctttgtgcgc gggtcgtgtt caggatgatg tcgatgccgc
  1157281 ggagccgtat atgggcggcg tcgccgaagg gggcgatact ctcgccgaag cgcatttccg
  1157341 cattgcgcac gagcttgatg accttgacga tgccgtcgat cggtcgacct gtgcctggcg
  1157401 cggatttcgc gccgaagcgc aaggggattt cggcgccttc gcccgccgcc atgcagatct
  1157461 gcaccgccat gggatcccag atcgtgccga ccgcagtgtc ggtcgccttt ctcgcaagca
  1157521 attcctccag cacgaccgtc gcatcgcctg cggttccccc gccgggattg tcccacatgt
  1157581 cggcaatcac cactggcccg gacggagccg cgatcgcctg cgccacggcc tggtgcgcgt
  1157641 cgatttccgg catgcggtaa gtgccgcggc gggagaagag ttcaaggccc agctcgcggg
  1157701 caagcgcctt gcctttctcg gccttgccgt tggtcacgac gagcatcttc gtgcccattt
  1157761 ctgtcacgtc accggccatg aagccatgta cgacggacaa tgagagcaca tcggcgtcgt
  1157821 gccgctcgat ctgcatcaat ctatctacga agctgcgcat cggctcgcgg gaggtgggga
  1157881 aaacgtctat catccggcag tcgaaaacgg acatcaccgg cgtgacgcgg ccctccagcg
  1157941 tgtcgacggc gacccgccag agatcctcgg cacgctcgac gaaatcggtg tgcgggaact
  1158001 ccttgaagaa aacgaagaag tccgcggctg caacgcgtct attcgtaaga tggctgtggg
  1158061 ggtcgagttc ggcgcagacg agcacctccg gacccacgag ttcgcgcacg cgctggagca
  1158121 ggtcgccttc ggtgtcctcg tagccgtcgg cgaccatggc tccatgcagg ccaaggatca
  1158181 cggcgtcaat gggcagggcg gcacgcaact ggtccaggat ctcgtcgcgc agatcctcat
  1158241 aggttcgccg gttgacgaga ccggccgggt ctgcccaggc tgcggtgccc tcgatcagta
  1158301 tccatccctt ttccgcggcc acccgccggc ccacggtaat cggtgccgtg cagagcgtcg
  1158361 gcgtttcggg gtgctttccg ggcgaagcgt aaagcgaggc ctcgaatgca cgcctgtcga
  1158421 tgcaaatggg ggagaaagtg ttcgtctcgg tcgcgagcgc cgccgtgaag atgcgcaatg
  1158481 tcttcgtctt tgccgtcacc tcggttcacc ccatcggatt ggggagatag ccggtgaagc
  1158541 cgcatactct ccaacggcta agatggagcc ggcaataata aactgtctgc cacttcatca
  1158601 catcgaagct gccgttcgct ttcttcactc cgccatcgaa cttcttgcgg gcgagtgcga
  1158661 gctctccact gatttcgatg tcttccaagg tcgtcgtccg gaaaatggct tcccgcgggt
  1158721 cctcggcgaa agactgccgt gcgaaatcct gcgcctggcg caaccattcg tcgcgatatt
  1158781 cggccagaga aggaaaggtg agccgccact tgtcggggtc cgcctctcgc cttccgtcta
  1158841 taccgatgaa gctttcctcc acgaaatcct cggcgaccat cgaccagtcg gcggccagga
  1158901 aggcgtctat gtcgcgcggc accaacatct cccagatgga acggcgagcc gcgtcgtcac
  1158961 cggggaacgg attctggaag ggatcccgca tgtgtttcgc cctaaattga aattcttttc
  1159021 ataaataagc attttctctg gtcaaattcc gcattctatg atcatttgtc aacgaaataa
  1159081 gaaaataatt tgcagagaag attcgcatgt cgatcaagcg gtatggcgac gagcagactg
  1159141 gagcaggtgg aaaagccctg ccttttgcac gcgcagtcga ggcggatggc tggctttatg
  1159201 tctccggtca ggtcgcgatg gaaaatggcg agatcatcga aggcaatatc gtcgcccaga
  1159261 cgcatagggc gataggcaat ctactggcca tcctgaaaga ggccggctac ggtgtcgagc
  1159321 acgtggtgag agttggcgtc tggctggacg atccgcgcga tttctggagc ttcaacaaga
  1159381 tctatcagga ctatttcgga gctcatccgc ccgcgcgtgc ctgcgttcag tcctccatga
  1159441 tggtcgattg caaggtggag atcgattgcg tcgcctacaa gccgaaggac gcctgacagg
  1159501 gagagggcgc cgtttgatgg atattttcgc gacactgcag gaagagaaag ggcggctctc
  1159561 tcaatcggag aaccgcattg ccgatatcct gctcaacgat ttcgagtttg ctgttaacgc
  1159621 ttccatcatc gagctcgccg gaaaagccga cgtttcgcca ccgacggtga cccgcttctg
  1159681 caggcgactt ggctgcgaga gcttttccga tttcaaggtt caactggcgc gtacacccta
  1159741 tgtcgggatg cgctacctga agccggagcc caagagccag gagcccggcg atgtggccca
  1159801 ggacatcatc accaaggcgc agaatgcatt gctcctctta catcggtcgc tcgaccttgc
  1159861 agccatagag cgcgcggccg accagttggc gcaagcggaa atgatctatg ccttcggttc
  1159921 cggcgggaac tcctcgatga tcgccgggga gttccagaac cgtctcttcc gcctcggcat
  1159981 gcgcatcact tcgagctccg accacagcat gcaaatgatg atggcggcgg ccgcacgtcc
  1160041 ggccgatgtc attgttggat cgtctttctc gggtcggaat gcggaactgg tgcgagcctt
  1160101 catccttgcg cgcgaggcca aggtgccgac gatcgcgcta acccagagcg gcagccccgt
  1160161 ggcgcaggcc gccgacatca ccgtgccggt cgacctgccg gaaggaaaca acatctatcg
  1160221 ccccacctcc acccgcatcg cctatctcgc tttgctcgat atcgtcgcga gtcttgtcgc
  1160281 ctatcgcgtc cagccgcagg caaccgtgac cctcaggcgc atcaagcagc agctcgtggt
  1160341 gcacagggat ggcgacgacc ggcagcttat gggagactga cgtgccacaa ggaacgccta
  1160401 ttccgaagtc cgtagcgatc gtcacgggag ccgccggcga catcggccgt gctattgccc
  1160461 ggcgcctgcg tgacggacat gataccgtcc tgttagccga catcgagggc gaggcggccg
  1160521 agagaacggc gcgtgatctc ggcggagcgg agcggttcgt ggccgtcacc tgcgacgtga
  1160581 cggacaccgc aagcgtatcc gcaatggctc gggcagccgc ctccttcgga accgtgcgta
  1160641 cactcgtgaa caatgcgggc gctgcgcgcg ccgtcagcct gcacgacacg acgcaggata
  1160701 catggcgcgc ggacaatgcg ctcaacctcg aagcggcctt tctctgtttc agggctgtcg
  1160761 aggaaatgct gaaggagagc cggggtgcgg tcgtcaacat cgcctcggta aacgggatga
  1160821 acgttttcgg ccatcccgcc tacagcgccg ccaaggctgg ccttttgcac ctgacccggc
  1160881 tgatcgccgt cgaatacggc aagttcggca tccgcgcgaa tgcggtcgcg ccggcgacgg
  1160941 tgcgcacgcg ggcctgggag gcgcgcgcag ccgccaatcc cgatgtcttc gaagaggcga
  1161001 agcgctggta ccccctgcag cgcatcgtcg atccgcagga cgtcgccgag gccgtccatt
  1161061 tccttgccag tcccgccgcc ggagccatct ccggcatctg cctgccggtc gactgcgggc
  1161121 ttaccgcggg ccatgccgaa gtcgcccgga ccttcacgca atcgatccac tactgaccta
  1161181 tccaccttgg gagattgttc atgctgcagg ccgcttatcg ccttgaatct gcctggcaac
  1161241 cggatggtgg cccattcggg cgcttcacct tcagcctctt taacctttcg ggcgagccgc
  1161301 ttagcgactt tcggctcgtc tacacgtcgc tcacccgcgt catcgatccg gacgcatgcg
  1161361 agaatgcggt cttcctccgc aggaatgcca atttccacga gttcgcgccg cccgaaggac
  1161421 tgacgcttgc ccacggagag cactggacat tcatgatcag cggtctgcac cggcaggcga
  1161481 agcattgcac cgacggggcg aagtcggcct atctgacgct cgccgatgga agtcatgtcg
  1161541 ctgtggcggt ttccgacctt cgtctggagg gcgccgtaag cgagccgccg ccggagcgcc
  1161601 tccccgaagg ctggctcgac cttcctttcg cgctgcagcc ctggcccgcg gagatcgatg
  1161661 cagcgcccgg agacctgctt ccggatttcc tctatcctgc ggcgggaagc gctgcggacg
  1161721 agatcgaggc ggtctccaac gtactcgcgc tcttccacag gctgttttcg gcgggtcacg
  1161781 ctccattcag ccttgcgcct tcctcccagg ggcggccgat catgttcaaa aaggcagccg
  1161841 agctcggcgg agaagcctac aggcttcatt tttccgacga ggagatccgg ctcgactatg
  1161901 gagctgccgc cgggaggcaa tacggcctga cgtccctcgc ccaactgatc gacggtgccc
  1161961 gcaaccacgc cgggagtttc agttttccgg tatccggtgt aatcgcggac gggccgcgct
  1162021 acgggtggcg cggctgtcat ctcgatgtgt cgcggcaatt ctatccgacc gccgacattc
  1162081 tgcgcctcat tgatatcctc gcctggttca agctcaacat cttccattgg cacttgaccg
  1162141 atgacgaagc ctggcggctt gaaatcaagg cctatccgac gctcacgacc ctgggcgtca
  1162201 tgcgggggcc ggacgagccg atgctgcctc agctcggcaa cggcgccgaa ccggtcggcg
  1162261 gcttctacag ccaggaggaa gcaaaggcga tcgtcgcgca tgctgcggcg ctcagcatcg
  1162321 aagtcgttcc ggagatcgac attcccggac acagcactgc cgcgctcgtg gcgattgccg
  1162381 aactctccga tggacaggag gcgccggaaa gctaccattc ggtccagggc tatcccaaca
  1162441 acgcccttaa ccctgccatt ccgctcacct acgaattcct cgagaaggtg ttcgacgaaa
  1162501 tggtcgagct cttcccgagc cgatatatcc atgtcggcgg tgacgaggtg gcagacggtt
  1162561 cgtggctcgc ttcgccgctg gcgcgaaagc ttatggaaca ggaaggcatt tccggcacct
  1162621 tcgcactgca gtcctatttc ctaaagaaag tgaaacagat gctgacggcg cgaggccgca
  1162681 agcttgtcgg ctggaacgag gttgcccatg gcggcggggt cggaacaaag gacacgctgc
  1162741 tgatggcttg ggagaacccc aaggttggga tcgagctggc acgcgagggt tacgacgtcg
  1162801 tgatgacgcc cggccaggcc tattatctcg acatggccca ggcggatgcc tggcaggaac
  1162861 ccggtgccag ctgggccggc acggcaacgc cgtcgcacac ctacgcctat gaggcggaag
  1162921 gggagttccc gaaagagctg aagagccgca tgaagggcgt ccaggcctgc atctggtccg
  1162981 agcatttcct ctcgcgggga tatttcaacc gcctcgtctt tcccaggctg ccggcaattg
  1163041 ccgaggcggc ctggacgccg aaggacaaga aggattggtt gcgctttgcc gcgatcgcgc
  1163101 cattgagtcc cgttctgtga tgtcaagcgc catgcggatc gccgtcggtg gaatccatac
  1163161 ggaatgcagc acctattccc ccgtcctgat gacggttgaa gacttccggg tgctcagggg
  1163221 agaggatctt ctgaattcgg actatttcgg cttcctcagc gcggagggga tagatcacct
  1163281 tccactgttg catgcgcgtg ctgttcccgg ggggccggtc tcgcgcccgg cttatgatgc
  1163341 tctcaagagt gagttcctgg aacgcttgaa ggcggccctg cctctcgacg ggctctacct
  1163401 agccatgcac ggggcgatca aagtggacgg aatggacgat gccgaggggg actggatctc
  1163461 cgccgcgcgc gccattgttg gcgccagctg cccgctcgct gtgagctacg atctccatgg
  1163521 caatgtcagc cagcggatca tcgatcagat cgacatcttt gccgcctaca ggaccgcgcc
  1163581 gcatatcgac acgcgcgaga cgatgatgcg gtcctggtcg atgctggtgg aagccctccg
  1163641 ctcggggacg cggcccggcg tcgcctgggc gcgcgtgccg cttctccttc ccggagaacg
  1163701 gacctcgacg gaggatgagc ccgcggcggg cctatatcgc ggcctcgctg acattaacag
  1163761 gcggccgggc attctcgacg ccaatctgat ggtcggctat gtctgggcgg acgagccgcg
  1163821 cgcaaccgcc tgtgccgtcg tcaccggcgc tgacaaggaa gctgctacta aagcggtgga
  1163881 ggaaatcgct gcaagctact ggttcaatag ggaagagttt cgtttcgggt caatctctgg
  1163941 gtcgcttgcg caaatgctcg gcattgccga gagtgcaaaa acggcgccgg taatcctcgc
  1164001 cgattccggc gataacccca cgggcggcgg cgttggtgac cgggcggatg tgttgatagc
  1164061 cctgatcgag cgcggctggc gcgacgcgct gatcgctggg attgccgatc ggccggcagt
  1164121 cgatgcctgt ttcgcggctg gtacaggcgg gatcctgaaa tttcgggtcg gcggcagtct
  1164181 cgacacgtcg agcccgtccg ccgagatcga ggccaaggtg gttcgccttg atgacccggg
  1164241 acccgccacc gagcggcagg ctgttgtcga ggccgcgggc atcgagatcg tattgtcggc
  1164301 gcggcggcgc ccctatcaca atatcgagga ctttactcgc ctcggtctcg atcccagggg
  1164361 tgtgcggctg ctcatcgtaa agtccggcta tctttcgccg gaacttgcgc cgatcgccaa
  1164421 tccgagcctg atggcgctga cggacggcgt cgtcaatcag gagatagaga agctcgccag
  1164481 cctgcggcgg gaacggccga tcttcccctt cgaccgtgat ttcgagttcc ggcccagcgc
  1164541 caggctgtcc gcccgctgga tttgagacag tgaaaccgcc cgtcttttcg ggcggtttcg
  1164601 gcagaccttg gcccttgtgc ggacccgcct atatgccttc ctcgcttctg atcgccatgc
  1164661 gcaatccggt catccggaca agcatgttcg ccattgtcct gttcggtttt tcgggcgctg
  1164721 ctacgtcgcc ctaccagtca gtcgtcggca tcactgaact gggcttgagt gacgggctct
  1164781 attcggcact gatcttcgcc gcggccctgg tcaacgtcgc gctaagcgtg acgatcggca
  1164841 ttgtagccga tcgcgtcggc aattaccgga ctttgatgct ggcggtcatt ctctgcggcg
  1164901 ttgcgggcta cggggcggtc tatctgctgc caacgaaatt gagcttcgtg cttgcagcac
  1164961 tcattttgtt gccggcttac ggagcgctca atcctctact cttcgcctat gtccgcacgg
  1165021 ctgcgaagga catgggaggt aggcatgcgg ctgcagtcaa ttccgccatt cgcgctgcca
  1165081 tatcgctttc ctgggtactg gtcccgggac tggtcggatt ggttctgtcg gcacacggca
  1165141 gcatgctgcc ggcctacctg ctggcaagcc tcggctgtct cgccaacttc gtgcttgttt
  1165201 tgcggcggct gccgcccaag gcggctgtcg accaagcttt gggcaagcgc ctctcctttc
  1165261 tcgcgtcctt cggcgagata ttgtcattgc gcgttgtgtt aaggcttctc gccatagccc
  1165321 tgatctcctc gaccctgcac gtcaatgcgg cggtgctgcc actgatcgtt acaggtgcgg
  1165381 tcggcggcga cgtgggcgac atcggcatta tcgtcggcat cgttgcgctg ctggaggtga
  1165441 ttttcatcct ggtatgggga cgtatccagg acagcctcag ccatatcaac gcactcgcgc
  1165501 tcggaactgc gatctatgtg gtcaacatgg ccctgctggg gctctcggcc gagcgctggc
  1165561 acatttatgc gctgacgctc gtaagcgctt tcggcgcagc ggcgctgatc agcattccga
  1165621 tcacatatct gcaggaactg atcgcagacc ggcccgggct cggaagctcg ctaatttcgg
  1165681 tgaatatatt cctcggcgcc ggcctcggcg ccgctctgtt cgcgctcgga acgcgcatca
  1165741 gcgactattc aggaacagcg cttctaagct ccctcgcggg cgtggccggt ctctcgctgc
  1165801 ttctttttct ggatggcggg cgagggaaag cctctgcgct ctgaacccgc cccaacctca
  1165861 tccccatgct cgttgtcatg gggatgcaga aggtgaaacg gccggagctt cagatcactc
  1165921 gcccaatatg cccggcaggc ggaggccttt ttcgcgggcg cagtccaatg cgatgtcata
  1165981 tccggcatcg gcgtggcgca tgacgccggt tgccgggtcg ttccacagca cccgctcaac
  1166041 gcggcgtgcc gcatcgtccg taccgtcgca gcagatcacc attccggaat gctgcgagaa
  1166101 gcccatgccg accccgccgc cgtggtgcag tgatacccag gtggcaccgg aggcggtgtt
  1166161 gaggagagcg ttcaggagcg gccaatcgga gacggcatcg gacccgtcct tcatcgcttc
  1166221 ggtctcgcgg tttggcgagg cgacggagcc ggagtcgaga tggtcgcgcc cgatgacgat
  1166281 cggcgccttc agctcgccgc tgcgcaccat ctcgttgaag gcgaggccga ggcggtggcg
  1166341 atcgccaagg ccaacccagc agatgcgtgc gggcaggccc tgaaaggcga tgcgctcgcg
  1166401 cgccatgtcg agccagttgt gcaggtgctt gttatccggc agcagctcct tcaccttctg
  1166461 gtcggtcttg tagatatctt ccggatcgcc cgagagagcc gcccagcgga acggaccgat
  1166521 gccccggcag aaaagcggac ggatataggc cggcacgaaa ccggggaaat caaaggcgcg
  1166581 ctcgagacct tcgtccttgg cgacctggcg gatgttgttc ccgtagtcga gcgtcggtat
  1166641 gccggaatcc cagaaggcaa gcattgcttc gacatggtcg cgcatcgacg cgcgggcggc
  1166701 cttctcgacc gtcttcgggt cgctctcgcg cttggccttc cattcggcga tcgtccagcc
  1166761 cttcggcagg tagccattca ccggatcgtg ggcggaggtc tggtcggtga cgatatcggg
  1166821 gcggatgccg cggcggacca tttggggcag aatttcagct gcattgccga gaagaccgac
  1166881 ggacttggct tcgccggctt tcgtccagcg ctcgatcatt tccatggctt cctccagcgt
  1166941 ctcggccttt tcgtcgaggt agcgggtacg gaggcggaaa tcgatcgaat ccgggttgca
  1167001 ttcgacggcg aggcagcagg ccccggccat gaccgccgca aggggctgtg ctccgcccat
  1167061 accgccgagg ccgcccgtca ggatccactt gcctttcagg ctgccgccat agtgctggcg
  1167121 gcccgcctcg acgaaggtct catacgtgcc ctgcacgatc ccttgagtgc cgatatagat
  1167181 ccacgagccg gcggtcatct ggccatacat ggcgagaccc ttcttatcca gctcattgaa
  1167241 atgatcccag ttcgcccagt gcggcacgag attggagttg gcgatcaaca cccgcggcgc
  1167301 atcccggtgc gtgcgaaaga ctccgaccgg cttgccagac tggacgagca gggtctcgtc
  1167361 ttcgttcaga tacctgagcg aggcgacgat gcggtcgaaa tcggcccagg tgcgtgcagc
  1167421 gcggccgatg ccgccataga cgacgagttc gtgcgggttc tcggcgacat caggatcgag
  1167481 attgttcatc agcattctga gcggcgcttc ggtcagccag ctcctggcgc tgatctcggt
  1167541 gcctcgcggg ctgcgtactt cgcgaatatt gtggcgcggg ttgttcatgt tcatgcctcg
  1167601 ctccctgtcc ttttgagttc gtttgctatt ttcccgatgc gttccagaat tgccgccaga
  1167661 ggccggcgga gcctttcggc tttcgccgca tccagggcga agggcggcgc ttccgtcgcc
  1167721 agatgcgtcg attgcgccag ttccatctgg atcgcgtgca caccctgttc cgggcggcca
  1167781 taatggcggg tcgtccagcc gcccttgaag cgaccattta gagtatggct gtaaccttct
  1167841 gtttcagagg cgatttcctc gaccgatcgc tcgatttcca aagcgcaggt tttgcccctg
  1167901 tcggtgccga tgttgaagtc cggcagcgtg ccttcaaaaa ggaagggaat atgtgagcgg
  1167961 atcgaatggc aatcatagag cacggcaatg ccgtggatcg ccctgacacg ggcaatctcc
  1168021 gctgcaagcg ccgcatggta gggcgcgtga aaatcgcgca ggcgctctgc gatgtcggcc
  1168081 tccgccggtc cttggccttc tttccagatg ggctgaccgt cgaagtcgct ttcgggcacg
  1168141 agccccgtcg tgttctggcc gggatagagg ctgacgccat cagggtcgcg attggcgtct
  1168201 atgacatagc ggtgaaaggt cgcgcggaca gtcgtcgcac ccgggagcag accttcgtag
  1168261 agttcgtgga tgtgccagtc ggtgtctgcg agaatgcggc cattgtcgtt gagccgttcc
  1168321 cagatcgacg agggtaggtc cgtccccgta tgcggaaagc cgaggatgac gggcgaattg
  1168381 cctcgccgga cttcgaagac ggccatgtca gttctccagt ttgggaagaa tgccggcgga
  1168441 gacggcggcg gcgagctgac ccgacgccac gagataggcc gcggccttca ggtcgtcggc
  1168501 catgtagcga tcttcctcga tgctgggcga gatgctgcgc acggcagcgg cggccttctg
  1168561 aagttccggg ctggtggtga gcggcgcgcg gaactcgata ccctgcaccg cagcgagcgc
  1168621 ctcgatgccg acgatcgcaa agaggttgtc cgtcatctgc agaagtcggc gcgcaccgtg
  1168681 gcaggccatg gacacgtggt cttcctgatt tgcagacgtg ggcgtcgagt cgacggaggc
  1168741 tggatgggag agctgcttgt tttccgacat caacgccgcc gacgtgacct ccgcaatcat
  1168801 cagtccggaa ttgagacccg gtttcttggc gaggaaagcc ggcaggccgt agctgagcgc
  1168861 ggggtcgacc agaagggcga tgcggcgctg ggcaatggcg ccgatttcgc acaccgcaag
  1168921 cgcgatctgg tcggcggcaa aggctaccgg ttcggcatgg aaattgccgc ccgagacgac
  1168981 ggaattgtcc gaaagcacca gcggattgtc ggtgacggcg ttggcttcga tcgtcaaggt
  1169041 ggctgcgacg gaacgcagga ggtcgaggca ggcgccgtcg acctgtggct ggcagcggat
  1169101 gcaataggga tcctgcacgc gctcgtcgcc ctcgatatgg ctttggcgaa tcggggagcc
  1169161 agtcagcagg tgccgtaagg cggcggccgt gtcgatctgg cctttatggc cgcgaagcgt
  1169221 atgaatatcc ggatggaagg gggcggaaga gcccatggcc gcgtcggtcg aaagggcgcc
  1169281 ggtgataagt gccgcctggc cggcgcggtg ggcgcggaag agcccggcaa gggcgagagc
  1169341 cgtcgagacc tgggtgccgt tgatcaaggc gaggccctct ttggcggcaa gcgtgacggg
  1169401 agaaagcccc gcagcccgca gcgccgctgc acccgccatg cgttcgccgg catagaaggc
  1169461 ctcgccgtgg cccatcatca ccgcggccat gtgcgcaagc ggcgcgaggt ctccggacgc
  1169521 gcctacggag cctttctccg ggatgagcgg gatcacgccc ttgtccagca tcgcttcgag
  1169581 gagccggacg agttcgagcc gcacaccgga ggcgccgcgg ccgagagaga tcagcttcag
  1169641 tgccatgatc agccgcacga tgttttccgt gagcggctgg ccgacgccgc agcaatggga
  1169701 gaggatcaga ttgcgctgca acgtttccac gtcggcgctg tcgatcttga tcgaagccag
  1169761 tttgccgaaa cctgtattga tgccgtagac gggcgcattg cccgcgacga tctcggcaat
  1169821 ccgcgctgca gccttggcca caccagcatc gaaggcaggg tcgaggcgcg ccggcgcgcc
  1169881 agtccagtat atcgtttcca gatcgctgag cggaaccgag ccgggcctga gaatgatggt
  1169941 catcgggaaa ccctttcgcc cttgaaaaca cgctcgcaca ggggattgaa gccgacgcgg
  1170001 tagatcagct ccgccggttg atcgatgttc cagatcgcaa ggtccgcgga cttgccggct
  1170061 tcgatcgtac cggtctcgtc gagcaccccg agtgcacggg cggcctcgcg agtaactccg
  1170121 gcgagacatt cctccaacgt caggcggaag agcgtcgcgg acatgttcat tgtgagcagc
  1170181 agcgaggtga gcggcgaggt tccgggattg caatcggtgg cgatagccat gcgcgtcccc
  1170241 gccgcgcgga gtgcttcgac gggtggaagc tgcttttccc ggagggtgta gaaagcgccg
  1170301 ggcagcagga cggcgaccgt gccggccttt gccatggcgg cggcgcccgc agcgtcgaga
  1170361 tattcgaggt ggtcggcgga aagagcgctg taggaagcag cgagctttgc gccgccgaga
  1170421 tcggaaagct gttcggcgtg aagcttcacg ggaaggccga gcgacttcgc cttgtcgaag
  1170481 accaaggcga tctccgccgg cgaaaaggct atgccttcgc agaatccgtc gacggcatcc
  1170541 acaagccctt ccgtatgcgc tgcagcgagg cccggcagga cgacctcggc gatgtagtcg
  1170601 ccgtttcggc cctgatatcc cggcggggtc gcatgggctg cgagatagct ggtgacgatg
  1170661 cgcaccgggc gcagggtctc caaccggcgg gcggcgcgca gcatcttgag ctcggtctcg
  1170721 acgttgagac catagcccga ctttacctcg acggtcgaaa cgccctccgc gagcagggcg
  1170781 tcgagccgtg gcagtgcggc cgccacaagt tcgtcgacgg aaagggcgtt ggtcgcctcg
  1170841 acggtcgaag cgatgccgcc tccggcgcgg gcgatcgcct cataggtcgc gccttcgagg
  1170901 cggagctgga attcccgggc ccggttgccg ccatgaacga tatgtgtgtg gcagtcgatc
  1170961 aacgcggggg ttacccagcg gccttcgcaa tcgaagatct ggtctgcgcg cgcaagctcc
  1171021 gaggtgagac cggcctcggg gccggcataa acgatccgct cgccgcgagc ggcgacgacc
  1171081 ccgctctcga cgactccgag ggtgcccaga tcttcgcgaa gcgtcgcaag gcgtgcgtta
  1171141 cgccagaggc tggttctgac agggcctggg ttgtcgtttc tgtccataag gctccaccct
  1171201 tctttcctga taatgtatat acataaagcg gagcatgaca agtgggaaat atgaatccgt
  1171261 cagataacgc ggtttgagcc gcgggccaga agcacaaaga agccccgaac tcccgtccgg
  1171321 ggcttgtcga gaggaccgtt ggtttgggcc ttaggccggt tatccgaagc ggacgccgtc
  1171381 ccgccgcggg ctgcggacga tgtcggtcta ttccgccgcg acagtggcca agcgccgccg
  1171441 gtgggagcgc agccctgcat aaaggaccgc aagcgaagcc accggaaaca gcgcggcgaa
  1171501 gaagccgaga tcggctgcag ccgtattctc gagcacgcgt ccgccgatcg ccgtgccggt
  1171561 cgcgatgccg agatagatcg ccgaggcgtt gagcgacagg gtcagatgcg cgacctcggg
  1171621 tgcgaagccg acgatacggc tcgcctgggc cggcggaaag gcccaaccta caatgcccca
  1171681 tggcaccatg atgccgatca gcagcaagcc ggcgagatca cgcgtgagaa ggtgcaggcc
  1171741 ggtggcgatc atcaacgaga ccaccagcgc cgagatcagc gaagctgtca ccacgcgcgt
  1171801 ggcgccgagc cggtcggcca gatagccgct ggagagattg ccgatcaccg cgccaacacc
  1171861 gaaggcaagc agcaggccag gtagcgccag ctgcgaaagc ccagccccat cgatcgccag
  1171921 cggtgcaaga taggagatga tcatgaagcc gccggtgagg tagagaaatg tcaccgatag
  1171981 cgacgaagcg actcccggac ggccgatggc gccgaagcgc tcggacattg tcagcttcgt
  1172041 tccgctgagg ccccgcggca ggcgcagcca gagcacggcg gcgcaggaga gcccaagcag
  1172101 agcaatcgcc ccgaacgtgc cgcgccatcc ccagaaggcg gcgatcagcg cgcccagagg
  1172161 cgcgcccagc gccaccgcga acgtggtgcc gcccaccacg attgaaatcg ccagcgcgcg
  1172221 gtgctccgct ccggccagcg aaaccgccgt cgcttgcgct gtggccgcaa agaggccgct
  1172281 cgccattccc atcacgatct gtgcgaacag cagcgtcgcg aaggagacgc tcgttgccgc
  1172341 gatgcagttg ccgacgacga aggtaagcat cgcagccacc agcaatcgac gcctgtccgc
  1172401 cgcgccggcc aacgccgata gcagcggcgc gccgatggca taggagagcg cgaacagggt
  1172461 gatcaggtgc cccgcacgag gaatggtcgt gtgtgtgtcg gcggcgatcg agggcagaag
  1172521 gctcgagaat acgaagccga ccgtactcat ggtgaaggag ccaacggcga gccagatgag
  1172581 gcgcttgtcc atggggaagc cttcttattc aaaagatgtt gaactattga acttagtggc
  1172641 tggtcatgtc aatatggagt gacagcaatc ttcgagccaa atgactctac cacatccgac
  1172701 accagaccag atcgctctgt ccaatgtact cgcggccctc ggcgacccga cgcggctggc
  1172761 gatcgtgggc tatctcgcca gtcgagatgg acggccgacc atgtgtctga acttcacgac
  1172821 tttcggttcc aagaccaata tcagctatca tctcgccaaa ctgcgcgagg ctggcatcac
  1172881 gcgcaccgag gtgtccggca cgagccggtt gatcaccttg cggcgggacg atctcgacat
  1172941 tcgctttccc ggtctcctcg atcccatcat cgccgccgcg atggacctgc ccatggtcaa
  1173001 gatgatcgag gacgcagaga aggacgcttt ggcgaaaggc gagccgggat gacgatttcc
  1173061 ggtcttttat tgtcgtttgc ggatatgccg ctgcggctca agcgggatga tggctcctgg
  1173121 ccgagtgccg ctccaccagc gcgacgaatt gccggccggc gatttcgagc ctgtcgctat
  1173181 tgtcgatcac cgtgacgtcc ggctcggcga tcaggtccgg tgcctgccgc gtcagacgac
  1173241 gcaggacatc ttcttcgctc tcccggccgc gctccgccaa ccgcctcgcc agcaccggca
  1173301 ggtcggctgt gatcaccacg acagcaattt tgccgaacgc ctgacgaatg gcggggaggg
  1173361 cggcgcggct gccgttcacg atcgccgtca tgccggctgc cactttctcg gagatttcgg
  1173421 ccgggatgcc gtagctcaat ccatgcgcgc gccagaaaac ggcgaaaatg ccgctgcgtc
  1173481 gcatttcctc gaattccgcg tcggagacgc tctcgtgcac ctcgctgccc gcgtcggaag
  1173541 gccgtgtgat cacccgccgg acgaacagaa tatcggggcg ctccgcgaaa tggcgggcgg
  1173601 caaaccccat gacgctgtcc ttgccggcgc cgctcggtcc gacgacgacg atgagggttc
  1173661 cggttccttg ctcggcggcg gtcatgcgac acgccgacct tcgcgccaga cggagcggac
  1173721 gaccggtatg ccctccggcc tgcggacgcg tgcgagatcg gcacggaggc caacggcgat
  1173781 ccggccgcgg tcatcgagac cgaccgtgcg cgccggagtg gccgtcacca ttgcgatggc
  1173841 ttcgggcagg ccgatcgatt cgacctcatc cgcgagtatg aaaggcgcat gaatgaggct
  1173901 gaacggcacg taatccgaag acagtacgtc gaggacgccg cgctcggcga gatcacgcgc
  1173961 ggcgatgttg ccggaatgcg atttgccgcg cacgatattg ggtgcgccca tcagcacgct
  1174021 gagacctgcc cgatgggaag cttccgccgc ctcgaagctc gtcggaaact ccgcaaggcg
  1174081 aataccatag ccgatcgact cgtcgacatg ctcgatcgtg gcgtcgtcgt ggctggcaat
  1174141 cgtgatgccg cgttcggcgc aagctttcgc aagggcggtt cggtgcggtg tcgcatagcg
  1174201 cgccgacaat gcctgctggc gctcgatgaa cgaagcgaag gcatcatcgg tgagaccgcg
  1174261 cttggttttg tagtagagcg tatattggtc catcgtctgg aactgacgtt gaccgggtgc
  1174321 gtgatccatc agcgaaacga ggcggacctg cggatcgctc cggaagtcct cgtaatgctc
  1174381 cagcacgtcg gcggtcgaca cttcgcagcg caggtgaatg aggtgatcgg ccctcagtcg
  1174441 gccctcttgc ttggcctggg cgagcgcatc ggccatgctg cgcatctcgc ccttcgggaa
  1174501 gccgctatcc tcgtccgagc ccaggcgcag gcaatcgaag acggtggtga tccccgaggt
  1174561 gacgacctgg gcatcatggg cctggatcgc cgcgatcttc agccagcgca cgccgggacg
  1174621 cggagaataa tgcgcctcga gatggtcggt gtgcagctcg acgaggccgg gcagcaggta
  1174681 gtcgccctcg aaatcttcgc ccgcagcact ggctccttcg gaaatgtcgg cgatcttgcc
  1174741 gtcgcggatc agcaccgagc catcgacaat ccggtcctcc aagacgatgc gggcgttggt
  1174801 caaaacctgt tctttgggca tgtcatgcta tctttcgttc ggatgcgccg ccgagcggca
  1174861 gcagggaatg gacggtgaag ggggcgccac ggcgctcttc ggcgaaaagc gcaatcgtcg
  1174921 aaacggcaag ccgcttgccg ataaattcgg cgaacaccgt ctcgagcgcc ttcctcatgg
  1174981 ggcggtgcat ttcttccgga accggtcccg tcagcgtcag atggaactgg aattcatcaa
  1175041 agacgtatgg atagccccaa gccgccaggt actcgcgctg acgctgcgtg agcctctccg
  1175101 gattgcggcg ggcgagatca gcttccgaga gcgccgcccg gaatggctcg aaacggcgaa
  1175161 ccgcctgctc cgccaaatgc tgcagttccg ggcaagcctt ggccgagacg agcgcgaaaa
  1175221 acgggccgat ctgatgcagg gcgatcgacg gaacttcgaa cggctcgatc tctgccgcga
  1175281 actcatcgaa agccgcgatc aagtcggctt cgctgcgctg gggcgtaagc tcgaacggtg
  1175341 cctttaatgt cccatgaaag ccgtagcggc gcggttcggc cgtcagcacc atttggtctt
  1175401 cgcgccccag cgccggattt tccgggcagt ccagagcgcc gcctgtgaac gcgtcgcgtc
  1175461 ccagccaacg ggaagcggtc tgcgacagcc ggtcatcgga cggcggtgcg aagtagattg
  1175521 catagcgcac gggttcaaac tctctctatc agtcgcctcg gcgcaggtta ccccgagtcg
  1175581 agggttcgcg ggatgaaatg cgcagctagc cgatttgcat gacaacatca tgatggcatc
  1175641 ggcgcagagc gcaattcggt tccgaacggg atgaacccta tgcagctgtt cgttgcatcc
  1175701 cgcgctacag cgccgtgcgt cttatcagac gcacaacggt cgccgtagca ctttgatctg
  1175761 ctgcatgttt ttgtccttca gtcggatccg attgaaggga acattcagta ggctatccga
  1175821 atcaaattgt cattatccgg atcgggcccc aatccagtct accccccttc aatgtgcctt
  1175881 gcggcccatc aaccgcgacc ggcagatatt ggaaatgctg tcgaaaacga agaccacgat
  1175941 caagatcagc agcaccatat aggcgacatt ttcccaatcc gaattggtac gcatcgcctc
  1176001 ccagagcttg agcccgatac cgccggcgcc tacggcgccg ataatggttg ccgagcgtgt
  1176061 gttggactcc caaaaataaa gggcttggct ggcgaagacc ggcaggacct gcgggagaac
  1176121 gccgaagcgc tgcacggcca ccggcgcggc gccgaccgat ttgacgccct cgcgctgctt
  1176181 gtcgtcgatg ttctcgagcg cctcggaata gagtttgcca agcgtgccgg tgtcggtgaa
  1176241 gaagatcgcc gacataccgg cgagcggccc gggtccgaag gcgcgcgtga aaaacaacgc
  1176301 ccagatgaac atgtcaacgg aacgcaggaa gtcgaagaag cgcttgacga cctggttggt
  1176361 gatccggctc ggcgtgatgt tgcgcgctgc aagaaagcaa agcggaaaag cgatgaagga
  1176421 tgcgaaaagc gttccgacga aagccatgac gaccgtctgc aggagcttgg tccagacgtc
  1176481 caggtgctgc cattcggcat tgtagaggat attgtcccag gccagagaca ggttggatcg
  1176541 cgccggatcg atccgctcgc cggaagaaat caacgagagc acctcgccgt aggacttgcc
  1176601 gaagaagggc gaattggtgt cgaagaaaaa attcacccag ccgaagaagc gattgcggat
  1176661 ggaaatctcg tcgccctcta cctcggccca gcctgtggcg ccgaatgaca acgtcacttt
  1176721 ttctcccggc cgcttctgaa tggcccagga gggcaggacg ccttcaggcg tcacattgtc
  1176781 cgagccgtcg accttcagcg tgagggtatc gccgccatgc gtgatggtga cgcgtttttc
  1176841 ggcggcttcg atgcgcgtcg agcggccgat ggttaccacc gcatgcgtga cgacttcttc
  1176901 ggtccgtgtc gcggcgaccg tttcctgtgg cgttgcttcc gcactgccgc gcgccgcgtt
  1176961 cggtgccatg aagctgaagg aggaggcgct cttcggcttt tgagccgcgg cggccggagc
  1177021 cgcgacagtg cgcgttaccg tctccttttc gagcgagacc cattcgggat ccggattgtc
  1177081 cccaagcggc gaattgcgcc cgaaagacac gtgcatcgct ccgtcgggct cgatggcgat
  1177141 ctccggccgg acctcatagg atacccagtc ggcgaggtag gtgccggcga tcccccaatt
  1177201 ggcgttggca agcacatgcc cgatggagaa gaaccaccag ctgaagatca tgtagatgac
  1177261 gacgcctgca gaaatcagtg ccgtccggcg ccactttgcc gccgacgact tcaggagatg
  1177321 cgggtggcgt gccgcaatag cgtccatttc ggatgcgtcg aggttggtcg aggcaatcat
  1177381 gatgtcgtcc tattgcgcaa gctggaaggc ctggtcgcca acgagacggc gacgaagcca
  1177441 ggcggagaac tgatcgacgg cgaggatcgt ggcgaagagc aggaggacga tcgcgagcgt
  1177501 ctttgcttca tggccctgac cgatcgaaag gcgcaggagt tcgccgatgc cgccgccccc
  1177561 gacagcgccg atgatggtcg aggcgcgcac gttgatttca agccggagca ggaagtaact
  1177621 ggtgaagttg ggaaggacct gggggaccat gccgaaccag acccgttcga tccaattggc
  1177681 accgacggcg cgcaaacctt cctccggctt catgtcggca ttctcgacca cttcgaagaa
  1177741 cagcttaccg agcgcgccga tcgtgtggat ggataccgca gcgatggcgg gaataggccc
  1177801 gagcgagaga atggccagaa aaaagccggc gatgacgact tccggaaagg cgcgcaggat
  1177861 ctccatcagc cggcgtacga tgcctctgac ccagggattg ggcatcagat ttcttgcggc
  1177921 gaggaagcac aggatgaagc cgaagaacac gccgatcacc gtggaaaaga tggcgatgtt
  1177981 caccgtctcc agcatcttgt gaacatattc cgggatgtag aggctctccg tcagatagag
  1178041 gcgaccctcc ggataattgt atttgaagct gccgtcgtca tagggcgaag gcagatcgaa
  1178101 gagagcccgg ccgatctcga tcggatcgcg cggcatgaga tggcccacga aatcgaagaa
  1178161 gtgcggcagc cggtcgaaga acttgccggc gttcgaatgg ttggcgaacc agagcgaacc
  1178221 aaagagcgtc agtgcgagga tggcgagacc gagccaggta tagagtcggc gccgattgtt
  1178281 gagctcctgc cagtgtcgct cgataagggc gccattctcg ctgagatgcc gtgttggcac
  1178341 ggaagtgacc attgggtttc cggcaggagc cggcctctag agcggatgag gaaaaaatga
  1178401 gtgcgatttt ccgcccgcat gccgctgagc aggcgggcat tgcaagcgcc cgatagtaga
  1178461 acgccgaccg ccacaaagcg gtcggcgcag gatcatggct ttggcgctca gccgccgatc
  1178521 gtcgccttgc gggcgtcgat gatcggcttg tagaattcgc tgttgacttc gacgaagccg
  1178581 gtaaaatcac cgccctggat ggcggagaag caagcggcgt cggtcttcgg cagatcaatc
  1178641 atgaactgct tgaacttggc cttcatgtcg ccgttcaatg ccgtacgcac gacgatcggg
  1178701 ccgttcggga tcaacggcga cttccagagt tcgacgaggt cgttcatgtc gacgataccc
  1178761 ttgtcgacca tcttgcgcag gttgcccgag gtgtagccgt ccttgaactc gccgacgccc
  1178821 gagccgaagg ttgtgccggc atcgaaggtg cccttcacga cctcaagaac gaggttttcg
  1178881 tgaccgccgc cgaagccggt ttcaccgaaa tattccttca ccggagcgcc gatggcttcc
  1178941 ggcagggtga cgagcggaac gaggtagccc gaggtcgagt ccggatcggc gaatccgagc
  1179001 ttcttgccct tgaggtcttc gagcttggtg atgccggagt ccttccgggc gaccatgatc
  1179061 gaatgatagc ccgtggagcc gtcggtctgg acggttgtca ggatcggctc gaccgcatcg
  1179121 gctttggcca gatagatctt ggcataaccg gaggcgccga gttccgcgta atcgagcgtg
  1179181 ccgccgagga ggccctggat cacaccgtca tagtcggcgg ccgggaagag agagaccttc
  1179241 tcgacgccga tcgctgccgg gagcttgtcg accaggcact ggtagttacg aaggcggtca
  1179301 gcttcgtttt cgccaccgat gatgccgacg cgaaattcct ttagctcttc ggcctgggca
  1179361 tggccggtga gggcgaagag cgcgacagcg ctcagaaggg ctttcttaaa catgaggttc
  1179421 gttctcccgt tgtccggacg cgccggatgt tttcggtttc agaaggcgcc cttttcgcgg
  1179481 gcgtttcgat cgcggctgcc tcagaggccg gccagtgcca gcggcttcga gccggccgat
  1179541 gcggtctccc gcggggcttc cgtggggatg ttgatgctgg tcgaggtcat cgactcctcg
  1179601 atcgcggtat cgccgccata aatctgcgcc acggctgcgg aagtgaggtc cttcggctgt
  1179661 ccatcgaaaa cgacccggcc atgcgccatg ccgatgatcc gctcgcaata gttccgcgcg
  1179721 gtatccagcg tgtgcagatt ggtgatcacg gtgatgccgt cgcgctcgtt gatgtcgcgc
  1179781 agcgcgtcca tcacgatctt cgcgttgagc gggtctagcg acgcgatagg ctcatcggca
  1179841 agcagcactt tcggttgctg catcagcgcc cgggcgattg cgacgcgctg ctgctggccg
  1179901 cccgaaagcg tgccggccgg ctgaagtgcg gtctgctcga tgccgagccg ctccagtgcg
  1179961 ccgatcgcca tgatgcgctc atcgcggctg aacatgttta aaacgctcaa cacagtggat
  1180021 cggtggttga gccgcccaag gagtacattg gtcagcacat cgaggcgcgg caccagattg
  1180081 aactgctgga agatcatggc gcaatcgcgc tgccatttgc gcagggccgc cccccttagt
  1180141 gacgaaacct ctgcttcgcc gaaggcgatc gaaccggagg aagggtccac gagacggttt
  1180201 atcatgcgca gaagtgtcga cttgccggca ccggagcggc cgataatgcc aaccatctgg
  1180261 ccctgcggaa tgtcgaaggt aaccgagctg acggcggttt tcttgccgaa ctggcgggtt
  1180321 acgttcttca actgaaacat tggcagcagt tcctcttccg ggggaccgtt gatcggtatg
  1180381 accctgccat aaccgcgctt catgaaggcg cagtgtcagt ttcgtgtcgg ttctgttaca
  1180441 gtgcacaggg ccgcagcccc cggcaggttc gggcgcctac catggcggga aaggggatgc
  1180501 gggggcgcta ctatcggaag cggcgcgggt cgaaaacgct ggagtcgagg ccgtcagccc
  1180561 ggaagccttc cggtggtgcc gtatccgtca gaaggctcgc tgcgagcgca cccagcgccg
  1180621 gcgaagtgag aatcccatag ccaccctggc cggccagcca gaagaaatcc ggtcgctctg
  1180681 cgccaaagcc gatcacgggc aagcgatctg gcgaaaagct acgcaggcca gcccagctct
  1180741 tggcaatcct ttgcaccttg atcgtggtcg cctcctcgac gtagtgtgcc gcccaggcga
  1180801 cgtcgatttc ctccggctgt acgtccgaag cttcgcatgg cgttgcgtcg gcaggcgagg
  1180861 caagcagacg cccgccctcc ggcttcatgt aaaaatcctc gtctatctcg ttgatttccg
  1180921 ggagatttgc ggcatcgacg ccggcgggaa gatcgacggt gatggctgta cgccgatgcg
  1180981 gaacaatgcc ggcaggtttt acgcggaaga gcgtggcgat ggggtcggcc caggctccgg
  1181041 cagcgttgac gacgatcttt gccccgatct ccccgccagc cgtgcgcagc agccaggccg
  1181101 gtccatcatg ctgtgcgcca aggatctcct ggcgttcgag gatctcgcaa ccgttgcggc
  1181161 gggcaccttt gacgtagccc tggagcaggt tctcgacttc gatgtcccag aagttcgggt
  1181221 cgtagaatgc ggctgcgaca tactccgctt tgaggatcgg aacgcgggca atcgcttcgt
  1181281 ctttcgtgag ccgctcgatt tcaggcgtga acgcacgttc ttcagcgagc agtttctcaa
  1181341 atcgttggag tttctcggca ctggcgatca ttacgcctcc acgctgcctc aacagcggca
  1181401 catcgctgaa gccttccggc ggccgatcga agaaaccttt cgatatcgtg gcgagttggc
  1181461 agatttccgc cgcattgtac ctgagcacga attccgcggc cgaacgcccc gtactgtgat
  1181521 agccaatcgc ctcctcccgc tccaggacgg cgacggaacg atgcgggctg aggaaatagg
  1181581 caagggacag gccggcgatc ccgcccccga tgatcacgat gtcatagttt cgcatacacc
  1181641 ctgctcccgg ttgcgccgtg gaccatagga acagtggtga ctgcgctcaa atttatagtg
  1181701 attaataccg ttatcaatcc tgctgatggc cgcagtgatc cagcgcttcg gtgtcggcga
  1181761 catgggcgag gaaagcggct tcggccgggt tgagaatgga attcggattg gagatgcgga
  1181821 aaacgtcggt cgtcggaagg tcgcggtagg gcggcaactg ccacaactct cccgttgcca
  1181881 ccgacgggcg ggcgatatgg tcagggagca tgccgatgcc gacattggcg gcgatcagcc
  1181941 gcaagacttc ctcgacattg caggagacac cccgaacctg ttgtccgaag gagccgacgg
  1182001 cacggactgc ggtcacggaa ttcatgtgct gtccgccgag cacgtcggcg atgaaggcga
  1182061 catatggatc gccgcgcagg tcatggaaat cgacgtcgtc ggcgccgaaa agccggtggc
  1182121 cgcgcccgca gtagagcgcg tagcgctcgc gtatgtgaaa gctcttgctc aagccgtcgg
  1182181 gtatgatccc gtcgcaaagg cccagggttg cgatattgcg ctcgacagcg ctcaggacgt
  1182241 cgacggtcgt tgccaccgtt atggatatcg tcaccttcgg atgcatacga aagaagctgc
  1182301 tgagctttct gtcccaggcg ggattgtgcg cgtggctcac ggcatggata ttgagatggc
  1182361 cggtgatctc ttcgccggcc gtttcgagaa catgcggcag ccgaatgacg gctgcgaaga
  1182421 tatcgcggca ctgaaggtgc agtttttcac cggcttcggt caggtcgaag cgaccggggc
  1182481 ggcggtcgat cagtttctgc ccgatcgtct gctccagccg cttgagcgcc atgctgaccg
  1182541 ccggttgctg caggagaagc cggtttgcgg cggccgtgat gctgccttcc tcgacgacca
  1182601 cgacgaaggt gcgcaacagg ttccaatcga gattatgggc aaagcgttca aggcggttac
  1182661 tggtcatgat gcccgcggga gcgatggggt actttgtgca tattcagaag aatggccgct
  1182721 tgcacaagac cattccgcca aagcgccgac ctgatgaatc atgcaacagg cgcatgagcc
  1182781 agtgtttcaa tttcgtttga aagccttgac ccggcttgcc ataacacaga cgcgataatg
  1182841 cgacgggaga cagatatggc cggcaaaagc caattccaat gggacgatcc gttcctgctc
  1182901 gaggaccagc tgacggaaga cgagcggatg atccgggaca ccgcgcgcgc ctatgctcag
  1182961 gagaagctgc agccgcgggt gatcgaagct taccgggaag agacgacgga tccggcgatc
  1183021 ttccgcgaaa tgggcgatct cggccttctc ggggtcaccg tgcccgacag ctacggtggt
  1183081 gtcggtgcct cctacgtcgc ctacggcctg gtcgcacgag aggtggagcg cgtcgattcc
  1183141 ggctatcgct caatgatgag cgtgcaatca tcgctcgtcg tctatccgat ctacgcctat
  1183201 ggctccgagg atcagaagcg gaaatacctg ccaaagctta tcagcggcga gtggatcggc
  1183261 tgcttcggat tgacggagcc ggatgcgggc tccgatccgg ccggcatgaa gacgagggcg
  1183321 atcaggaccg agggcggcta tcgtctgatt ggctcgaaga tgtggatctc caacgcgccg
  1183381 ctcgccgatg tcttcgtcgt ctgggcgaag tcggaagcgc atgacaacgc catccgtggc
  1183441 ttcgtgctgg agaaaggtac caagggactt tcggcgccga agattgcggg caagctttcg
  1183501 ctgcgcgcct cgatcacggg ggaaatcgtc ctcgacaatg tcgaggtcgg cgaggaggcg
  1183561 ctgctgcctg atgtcgaggg actgaagggg ccctttggct gcctcaaccg cgcccgctac
  1183621 ggcatttcct ggggtgcgct cggggccgcc gaattctgct ggcacgcagc gcgtcaatac
  1183681 ggtctggatc gcaagcagtt caacaggccg ctcgcgcaga cccagctgtt ccagaagaag
  1183741 ctcgcggaca tgcagaccga gatcgcgctc gggctgcagg gctcgctgag agtcggacgg
  1183801 ctgatggacg agggccggat ggcaccggag atgatctcga tcgtcaagcg caacaattgc
  1183861 ggcaaggcac tcgatatagc gcggcaagcc cgcgatatgc atggcggcaa cggcatttcc
  1183921 gaggaatatc aggtcatgcg gcacatgctt aacctcgaga ctgtcaatac ctacgagggt
  1183981 acgcatgacg tgcatgccct gatcctcggc cgcgcccaga ccgggctgca ggccttcttc
  1184041 tgagcggcgc gatggaagcg ccgctgaagg gtattcgcgt cctcgaactt gcccgcatac
  1184101 tggctgggcc ctggatcggg cagacgcttg cggatctcgg agcagacgtc atcaaggtcg
  1184161 agagcccggc cggtgacgac acccggagtt gggggccgcc tttcgtgcag ggcgagggcg
  1184221 gggaaaggct ggatgcggcc tatttccacg cctgcaatcg cggaaagagg tcggtcgttc
  1184281 tcgattttac gaccgaggag gggcaggagg cggtacgccg gctggcgtcg cagtccgacg
  1184341 tcttgctcga gaacttcaag gtcggcggcc tggccaaata cgggctcgat tatgagagcc
  1184401 tgaggaaagt caatccgcgg ctcatctatt gctcggtaac aggattcggg caggaagggc
  1184461 cctatgctca tcgggctggc tacgactaca tcgtgcaggg tatgagcggc attatggact
  1184521 tgacgggtga gccggacggc gagccgcaga agatcggcgt cgccttcgcc gatatattca
  1184581 ctgggctcta tggcgtcatc gccgtgcagg cggcgctggc gcagcgggag cgcaatggcg
  1184641 cgggacagca tatcgacatg gcgctgctgg actgcatgac cggcgtgctc gccaatcagg
  1184701 ccctgaactt tctagtctcg ggcaaggcac cgcggcggct cggcaacgcc catccgaata
  1184761 tcgcgcctta tcaggtgttt ccaacctccg acggccatct catcgttgcc gtcggcaacg
  1184821 atcgccagtt cgtgaaattc tgcgaactcc tcggtcggcc ggacctcgcg tcggatccac
  1184881 gctaccgaac gaacgccgac cgcgtgcaga accgcgacag cctgaccccg gaactcgcgg
  1184941 cggaaacggc gaagttcgaa agggatacgt tgctcgccag gctcgaagcc tcaggggtgc
  1185001 ccggcggccc catcaacacc gtcgccgacg ttttcgccga tccccagatc atccaccggc
  1185061 agatgcgggt ggagacaccg cacaccggcg cggcgacagg aacctcgccg ggcatccgca
  1185121 cgccaatccg cttctccgat gcggcgctcg cgctcgaacg gggggtgccc cggttggggg
  1185181 agcatacgga agaggtgctg gcggagatag ggatgagttt gcttgagcct taaggatgaa
  1185241 tgctcccctc atccggcctg ccggccacct tctccccgca ggcggggcga aggagactcg
  1185301 tggccggcgt cgtgctcatc ccccgcccct ttgcgggaag gggttcctca tcgggttaac
  1185361 ccctaaactc gaggagaggc cacagctgga accttaattc ccttacgacc ccttcaaagc
  1185421 tcggctgaac acgcgagtca gccgttcggc gaaggcgcgg ggatcctccg gcttgtcgcc
  1185481 gtcgagaacg cgcgcctggt cgaacagcag cttgaccgcg tcctcgcgga acgtcttgtc
  1185541 ctcgccgggg cagccggcaa gggcggtgat cagctgatgc ccgggattga cctcgagcac
  1185601 tggttttgcc gcgctctcga ttcgcccggc cccctgcagc attttctgga gctgtaggtc
  1185661 cggaccctgt tccgttgcaa ccaggcagac ggcgctctcc gtcaggcggt cggaggtccg
  1185721 gacatctgaa acggcgtcgc cgagcgtctc cttggcgaag gccaagaaat cggtgaccgc
  1185781 gacacccgct tccgccgaag cggcggctgc cgcatcgttc ttttttgcga tgcccgccag
  1185841 atctgccgca ccttgcgtga tcgatttgaa cggcttcccc tcgaagtccg gtgccgtcgt
  1185901 cacccagaag ctgtcgaccg ggcacgtcag gagaagcact tcgatgccgc gggcgcggaa
  1185961 accttcgagc tgaggcgagg ccttaagctg cgcgaggttg tcgccggtca ggtaatagat
  1186021 tgccgtttgg ccttccttca tctccttgac gtaatcgctc aggctgcgcg gcttttcgtc
  1186081 gtcgacggtg gtgcggaagc gcgacagggc gaggagctgt gcccgtcgct cgaaatcttc
  1186141 gtagatgcct tccttgatca cactgccgaa gttttcccac agcttggcga aagcttccgg
  1186201 atcgctttcc gcgagctttt cgatgctggt gaggacgcgg ttcgtcaccc ccttgcggat
  1186261 gtttgcgaga agaggacttt cctggatcat ctcgcgcgag acgttgaggg gcaggtctgc
  1186321 cgtatcgacc aggccgcgta cgaagcgcag atagcgcggc agcagttccg cctcgtcggt
  1186381 gatgaagacg cgcttcacgt agagcttcat ccggcccttg cgatcgggat cgaagagatc
  1186441 gaagggcttg gagccgggca cgaaggcgag cgcggtgtat tcgtgacgcc cctccgcacg
  1186501 gaaatgcacc gtcagtgcgg gctcgtcata ctggccggcg acgccgcgat agaagtcggt
  1186561 gtaatcttcc gtggtgattt cgcttttctg cttcgtccag agcgccgtgc cgtccacgac
  1186621 ctgcaccggt tccgctccgg gcttttcgac aatcgagatc ggaaccggga cgtggccgga
  1186681 ttgctccttg acgatgcctt cgaccgtcca gcgcgacgtg aaagttttgg catcctccat
  1186741 cagatgcagc gtgatgcgcg taccgcgcgc gggcgcgtcg gcaaggtcga acgccgagac
  1186801 cgtgtagctg cccttgccgt ccgacgccca gagccaggcc ttgtcggtgc cggcacggcg
  1186861 ggaaacgaca tcgacattgt cggcgaccat gaaggcggag tagaagccca cgccgaactg
  1186921 accgatgagc tgtgcgccgt ccttgttctg cgccgcctct atccgctcca tgaaagcgcg
  1186981 cgtgccggag cgagcgatgg tgccgaggga ttcgacgagt tcgtcgcggc ccatgcctat
  1187041 gccattgtcc tcgatcgtaa gacgggcatt ctcctcatcg agcgtcagcg tgatgcgcga
  1187101 ggtggggtcg ctgccaagga gctccggcgc gacgatcgct tcgtagcgca gcttctcgca
  1187161 ggcgtctgcc gcgttcgaaa tcagctcgcg gagaaagacg tttttatcgg aatagaccga
  1187221 gtgcaccatc aggtgcagca gcttcgccac atcggcttcg aagacatgtt tctcgacgga
  1187281 cgtttcgact tcactcatcg cgttttcgga cctccttgat gtttgctccc aattggcaag
  1187341 ccgcggcttg aatttcaagg gtcgtcttgc ggcacgcctg cttcggtgcg aagcttcacg
  1187401 cgggcgctca acgccgggtg gcgcacctgc cggctgttgt gctgcagatc gaggaggaga
  1187461 catggtgtcg gaggtgatgg agctggcggc cgaaccgtcc aagtatgatc gcctgatcgc
  1187521 agcggcgcag gccgaggagc cggcggtcac actggtggtc catccctgcg atgagaccgc
  1187581 cttgcgaggt gcgctcgaag cagcgcagat gcgtcttatc acgccggttc tcgtcggccc
  1187641 tcgcgtcagg atccggagca tcgctgccga acatcgcctc gatctcggcc agtgggagat
  1187701 cgtcgacgtt ccgcacagcc acgctgctgc agcgaaagcg gtcgctctga tccgcgaagg
  1187761 caagggcagc ctcttgatga agggcagcct gcacaccgac gagctcatgc gagaggtggc
  1187821 cgccgccgct tcgggtctta gaaccgagcg gcggatcagc cacgtcttcg tgatggatgt
  1187881 gcccggtcat gccgacacgt tgttcatcac cgacgccgca atcaatatcg cacccgatct
  1187941 ggatgccaaa cgcgacatcg tccagaacgc gatcgacctt tgggtgacga tcggactcgg
  1188001 cgagccgcgc gttgccattc tttcagccgt cgagacggta acgatgaaga tcccctcgac
  1188061 gatcgaagcg gccgcgctct gcaaaatggc cgaacggggc cagatcaccg gcggtttgct
  1188121 cgacggacct ctggcctttg ataacgcgat cgacccggaa gctgcgcgta tcaaggggat
  1188181 tgtgtcaccc gtggccgggc gcgcccagat tctcgtcgtt ccggacctgg aggccggcaa
  1188241 catgctcgcc aagaatctga catttctggc ccacgccgac gccgcaggaa tcgttctcgg
  1188301 cgctcgtgtg ccgatcgtcc tcacctcccg ggcggattcg gtccgcacgc gcctcgcctc
  1188361 atgtgcagtc gcttcgctct ttgcggcccg gcggcgggca gcacaagtgg ctgtgtgata
  1188421 tggaagcggt tctcgtcgtc aatgccggct cgtccagtct gaagttccag atcttcggta
  1188481 tcgccggggg cgggctgcaa aggcaggtcc gcgggaagat cgacggcata ggcacgcacc
  1188541 cgcacctgaa ggcgagcaac gccgacggca cggacctcgt ggatcgtgct ctcgattcgt
  1188601 ctaccgttcg cgacctccct actgccattg cggaagcgcg gaactggctc ggcggcgtcg
  1188661 acggcatcga actgcgggcg atcggacacc gggtggtgca tggcggtccg gactacgttc
  1188721 gccccgtgct gatcgatgcg gcggtgctcg agcggctggc gagctaccag cacctcgcgc
  1188781 cgctccatca gccgaacaat ctcgcgccga tccgccttgc catggacatc aaccccgatg
  1188841 tgccgcaggt tgcctgcttc gacacagcct ttcaccgggg gcgtgccgag cacacagact
  1188901 gctacgctct cccgcatgcc ttctacgagg acggaatacg gcgctacggc ttccacgggc
  1188961 tttcctacga atatattgcc gagcggctgc gcgaggtggc tcccgacatc gcggggggca
  1189021 gggtcatcgt cgcgcatctc ggcagcggcg tttcgatgtg cgcgctgaaa gacgggcgca
  1189081 gtgtcgaaac gacgatgggt ttcacggcgc tcgacgggtt gccgatgggg acgaggccgg
  1189141 ggcaactcga cccgggcgtc atcctgtacc tgctcacaca tcacggcatg agcgcgcaag
  1189201 agatatcaga cctcctttac catgacgccg ggttgaaagg attgtccggc atatcgaacg
  1189261 acatgcgcga actttcggcg agcgaggacc cgcgcgcatc cttcgcaatc gatcatttcg
  1189321 tgcatcgctg ttcgctccat gccggcatgc ttgctgcggc cttgggaggt ctcgatgctt
  1189381 tcgtcttcac ggcaggcatc ggtgaaaatt ccgcaacggt cagagcccgc atcgccgaac
  1189441 gcctcgactg gctcggagcc gaactcgacg ctaaagccaa cgatacgggc gcgccggtcg
  1189501 tctccagagc cgggagccgc gtttcgcttc acgtcatacc gaccgacgag gaactgatga
  1189561 tcgcccgtca cacgcttgcg cttctgcgcg tttgatttgc cgcaccggcc gagtctagcc
  1189621 gttcagatat tgcccatgca gagatatttc atctccagat agtcttcgag accgtggcgg
  1189681 gaaccctcgc ggccgatacc ggattgcttg atgccgccga agggagcggc ctctgaagac
  1189741 attcggcccg tattgatccc gaccattccg tattccagcg cctcggcaac atgccagacc
  1189801 cgcttgaggt tctcggcata gaagtaggcc gcaaggccat agatcgtgtc gtttgcctcg
  1189861 gccacgacct gctcggcgct gtcgaagcgg atgatcgggg cgatcggccc gaatgtctct
  1189921 tcctgggcaa cacgcatgtc gtgcgagatg cctgtaagca cggtcggttc gaagaaggtg
  1189981 ccggccgtcc cgatgcggtt gccgccgcag cgcacttcgg cacccttggc aatggcatcg
  1190041 gacacatgcg cctcgatctt ctcgatcgca tgggcgtcga tcatcgggcc gatcgtaacg
  1190101 ccgggggcaa agccgtcgcc gacggtgagc tctcgcacgc gggtgacgaa cttctcggcg
  1190161 aaggcgtcgt gcaccgcggt ttgcacgtag atgcggttcg ctgaaacgca ggtctggccg
  1190221 gcattgcgaa acttggcctg aagcgcaccg tccaccgcct cgtcgatatc ggcgtcgtcg
  1190281 aagacgatga agggggcatt gccgccgagt tcgagactga ctttcttgat ctggtcggaa
  1190341 cattgccgca tcaaaaggcg cccgacctcg gtcgatccgg tgaagctgat cttgcggatc
  1190401 ctgggattgc tgcagagctc ccggccgata ggtgcaccct cggatgcgta taggagattg
  1190461 aggacgcctt ccggaaagcc tgcttgttcg gcgagcgcga acatggcccc ggccaccagc
  1190521 ggcgtctgct cggccggctt caggacaatc gtgcagccgg cggcaagcgc cggagaaatc
  1190581 ttgcgcgcaa ccatcgaagc cgggaagttc cagggcgtga tggtgccgac cacgccgacg
  1190641 ggctgcttga tgacgagcat acggcgatcg ttggcgggcg cagggaaggt ctcgccgtag
  1190701 acgcgcttgg cttcttccgc ataccactcg atgtaggatg ccgcgtgaag gacctcgccc
  1190761 ttcgcctcgc cgacgggctt gcccatttca gccgtcagaa tcgccgcgag gtcgtcgacg
  1190821 tgctcgacga tcaggtcgtg ccagcgacgc aggacgatgc tgcggtcctt ggccggcttg
  1190881 ccggcccata aaggttgggc aagggcggcg gcgtcgatcg cagcgcgcgc ctctttgatg
  1190941 cccatatccg gaagcttcgc cagcaattcg ccggtcgaag gattgaagac gtcgaaagtc
  1191001 ggaccggccc attctcctgc gggcagggcg acgctatcga gcgacgcgaa aagcttcggt
  1191061 tcgcggatgt gtccggtgag tgcaggcgtc agggccacgc aacgtcctcc cgcgatgcct
  1191121 gcggcggccg caagcctcgc ttctcttcct tgttacgggc gcagccaatg cgcccccggc
  1191181 atggctgacc gcgatagcgg ccgcctgtgc agccgtcaac cgcgcgcttc gaggatcgag
  1191241 gattcgagga tgtccagggc ttccgcgaag acatcatcct ggatcgtgat cggcgccaga
  1191301 aagcggatga cattgccgtg tacgccacag gtcaagagga tgagcccctt ttccagggca
  1191361 aggaggcgga ccttattggc gaattcggcg ctagggacgt tcgtcttcac atcgttgaat
  1191421 tcgacagcgt tcatgaagcc gggtccgcgg atatccacga tctccggcgc cttctcacgg
  1191481 attgccgcaa ggcgctgctt cagccggttg ccgagctggt tcgcccgttc gcatagattt
  1191541 tcctcggcaa tcacgtcgag cacggcatgc gcggcggcga tgccgagcgg attgccgccg
  1191601 taggtgccgc ccaggccgcc cggcccgggc gcgtccatga tctcggcgcg gccagtcacg
  1191661 gcggcgagcg ggaaaccgcc ggcgaggctc ttcgccattg tcgtcaggtc cggtgcgacg
  1191721 ccatgatgtt ccatggcaag cagcttgccg gtccgggcaa aaccggtctg gacctcgtcg
  1191781 gcgatcagca ggatgccgtt ctgatcgcag atctcgcgca gcgccttcat gaaggcggtc
  1191841 ggaaccggat agaagccgcc ttcgccctga accggctcga tgatgatcgc agcgacgcgg
  1191901 ttcggatcga cgtcagcagc gaagagcttc ttcagcgccg ccaacgactg ctcgacgctg
  1191961 acgccatgaa gctcgaccgg gaagggagcg tggaacacat ccgccggcat cgcgccgaag
  1192021 ccgaccttat atggaacgac cttgccggtc agcgccatgc ccatgaaagt gcggccatgg
  1192081 aaaccgccgc cgaaggcgac gatcgcctgg cggccggtcg cggcgcgcgc gatcttgacg
  1192141 gcgttttcga cagcctcggc accggtcgta acgaaaatcg tcttcttcgc gaagtcgccg
  1192201 ggcacgatcg cgttcaggcg ttcggccaga tgcacgtagt tttcgtaggg cacgacctgg
  1192261 tggcaggtat gggtgaagcg gtcgagctgc gccttgacgg cggcgatcac ctttgggtgg
  1192321 cggtggcccg tatttaccac ggcgatcccc gaggcaaagt cgatgtagcg gttgccttcc
  1192381 ttgtcccaga tttcggcatt ttccgcgcgc tcggcgtaga tctgcgtggt catgccgaca
  1192441 ccgcgggaaa tagctgcatt cttgcgatcg gtaaggctcg tcatcgtttc cgtcctggtc
  1192501 gagagagaat atattgcatt ttttctgcaa agtttcgtga caaggggtac atctttccgg
  1192561 ggagattgca aatcaaattt actgagcggc acagcactcg aattgatgga gcgcggaaaa
  1192621 ctgcttcaca cctttcctgg aagtactcta gattgccgca gcccgtggac ggcacggatt
  1192681 cgcacgcgag tcttacggcg caacgagggt atgaattgat gggcggtgtt ggtgccatcc
  1192741 gctacaaggt tgccgaggcg gcaaggctcg caggcgtttc ggcctcgaca ctcagattgt
  1192801 gggaaaccca aggtctcgtc gtgcccgagc gctcggcgac gggtcaccgg caatatacgg
  1192861 atgccgatct tgcccggttg aagcgtattt cctggttccg ctccgaacgc ggtctcaacc
  1192921 cggctgcgat cagggaggct ctcgaggcgg aaaatgcggc cgctgacgat gaaaacggct
  1192981 tggcggtgct gagcgacgag aatgccgagc ttcaggtcgg acggaagcta cgcagcctga
  1193041 gacataccgc cggtaagact ctggagcagg tggcaggcga catcggtatc gccgcctccg
  1193101 tgttatcgac gctggagagg acatcacagg gtgtgtcagt tgccgttctg cacaatctgg
  1193161 cggaatattt cgacaccacc gtctcaagtc tctccggcga agaagagaca aaggcacggg
  1193221 ctctcgtgcg ggcaggcgaa tggcgaaact ggccgcgcac gacaccgggc gttacggtgc
  1193281 agttgcttgc cgaaggcaag aaccagatgg attgccatcg cttcgttctg gcgccgggcg
  1193341 catcgagcga gggcgcctac cggcatgagg gagaggaatt cgtttatgtc ctctccgggc
  1193401 gtgtggagtt cgtgctggat tcggatcagt tctacgacct tcacccgggc gattccctct
  1193461 acttcgagag ccgccgccgc catgcctggt cgaacaggca cgacggcgaa accgtattgt
  1193521 tgtggatcaa cacgccgccg acattttgac agaacgctcg gcaatgaaga cgccgcttct
  1193581 cgcggcgaca tcagtgcgtc cgtgtagcag cggaatattg cgcgcaggcc acacccccac
  1193641 cctcgtaggg gcgtccaggc tatgttgatc gagcccggaa caaagtttgg cccgattccc
  1193701 ccattcagcc tcgaacagtt ctttagccta ccgaccacca gctgccgctg ggaagcgctc
  1193761 aggaaacggg attgcacagg gatgtacctg ttccatgagc ttgccggaga aatcctcaaa
  1193821 ggacgaccgc ggagggagtg ttgatgcagg tagtgcgcga ccagcagctt gatggcctga
  1193881 gagccgtcgc ggtcacaatg gtgctctacg cgcatttctt tgcagccgat ggatcgcatt
  1193941 ggggccatct tggcgtcagg ctgttcttcg tgctgagtgg ctttctgata acgcggctgc
  1194001 tgctcgacgc ccgcgacgct gcccgtttcg agccgagcac ggcgctgaag tccttctatg
  1194061 cgcgccgggc gcttcgtatt ttcccgcctt attttgccgt gctggctgcg gtgtttctcc
  1194121 tggacttgga gcgctccaag caggttatgg catggcacgg gctttacctg tccaacttct
  1194181 ggtatgcgct gcagaacgaa tggtcgccgt gggttctctg tcatacgtgg agcctgagca
  1194241 tcgaggagca attctacctc atctggccat tggtcgtgct gctcctgccg cgccgctcga
  1194301 ttgccggggt ctgcatcggc gtcatcgtct gctcgctcgt ctaccgcttc tactggccct
  1194361 tcaccggtac gccttcgctc gcgcgcgatc tcctgccgcc ggcatccatg gatgcgctgg
  1194421 ccgtgggcgc cttgttggct gcgcgtccat cctggcgtgc ggcttggccg cgatgggcgg
  1194481 aattgagctg gattcccctt tccatcgctt ccttcgccct ggtctggctg aagccggttc
  1194541 cgatgacccc ggtcatagcg tggctcgcat ggatcggact ggaggtggtc ccgctcttgc
  1194601 cactcgccat gctggtcggc agctgttcga aggggatcgg cgggattgcc gggcgggttg
  1194661 tcgcgctttc gcccgtggcg gctctgggcc ggatcagcta tggcgtctac ctctttcacg
  1194721 ccgtcgtact ggctgtggtc gtccaggcgc agccgttcat cccggtcaat gtcacggatc
  1194781 agggggtagg gcggttcgtg gtcgccggcg ctctgacact gatgctcgcc tcggcgtcct
  1194841 ggatcctctt cgaaaagccg ctgaacgggc tgaagcgcca ctttccctat gttcgtccgg
  1194901 agggagcggc ggggcccgta actgccgttc ctcgcgtccg tcccgacgag gccttgcaaa
  1194961 caccgcccct tcgatagcac ccgagttgaa ccatgccttt gcccctcgtc tccgtcctcc
  1195021 tacccgtcta caatggcgag ccatacattg ccgcagccct cgagagcgtg ttgcgccagg
  1195081 actaccaacg tgtcgaggtg atcgcgatcg acgacggatc gacggaccgg tcgcgggaca
  1195141 ttctcgaacg ctacgggaag accgattccc ggctttccat catctctcgc gaaaaccgcg
  1195201 ggctggtagc aagcttgaat gaagggcttg ctcttgcaaa gggcgagctt atcgcgcgga
  1195261 tggatgcaga cgatatcgcc tatccctcgc gtctttcccg gcaggtcgcg ctgtttggcg
  1195321 aagaaccgcg gctggccctc tgcggcaccg gcatcgacat gctcatcggc aaccgcatca
  1195381 tacgcggcag accaaatccc atctaccggc cgggaagcct gcgcaccctg tcgatgttct
  1195441 tcaccatctt catgcattca acggtggtct ataacaggac aatcattccc gacgagatgc
  1195501 tccgctacga ttcgaactat gtgcacgcgg aagacttcga tctcttcagg cggatcgcgg
  1195561 atcgctttcc ggttcatatg atcgacgagc ccctggttgc ctatcgcatc catgaagata
  1195621 gtgtcaccag caagcataag cggcagatgc gccgcaccca tctgagcatc gtggccgaga
  1195681 acctggcacg ggacgctctt ctcgatgatt ccgccgcgct cgaagcactc ggcgccgccg
  1195741 taacgggcga gacggtggca cgtcttgccg actgtgtcct ggcactcgaa cgtgcgattg
  1195801 cggcgcggcc ggtggaagtc cgtggtgcct atgaagacgg cgccctgtgc ttcttctatt
  1195861 tcctctatca gctcattgcc gacgaggagc agccgcggct gacccacgaa ttcctgacga
  1195921 ggacaggcaa atggggcctg atccgccgtc gcgaacgcta tgggctgctc gccgcgactc
  1195981 gggcaccgtg gtgcagccgg atttcgcttg cggcaagcag gcgggtggac cggctagcgc
  1196041 gccatctgca gtcggtaccg gcagcgaccg tgcttccaga acatggcttg acctgacatg
  1196101 gccccagaac cgctcgcaat gatgcaagac gatccgatag caccggatgc tcggcgcttg
  1196161 gtcgccgcct cgccttccgg tgagcccggg ccgttcgcca gcttcatcgt ctgcacgcac
  1196221 aaccgcgtcc acgcgcttgc ggcgtcgatc cggtccatcg agaccgccag ccgcgctcat
  1196281 gccatggtcg agagcgaact cgtggtggta gacaatggct cgacggacgg cacggcggaa
  1196341 gaactggccg gcatcgcggc aagaacgatg atgtcgatca cgctcctcac cgagcctcgc
  1196401 ccgggtctcg ccgcagcgcg caacacgggg atggcacgcg cgcgcggacg gatactcatc
  1196461 ttcatcgatg acgattgcga ggtggacagc aattacctcc gtgatctcga gcggcactac
  1196521 agcggtggtg atgaacaagt catccgcggc gggcgcgtcg agctcggtaa tcccgccgat
  1196581 ctaccgttca ccgtcaagcg ctcgaaggtg gcggcgcgcc tgacccgcga tgtccacccg
  1196641 ggcggattcg tccttggctg caacatgacc atgcatcgtg acattgcggc gcgcatcggc
  1196701 cctttcgacg agcggttcgg tgccggagcg ccgctgaaag ccgccgagga tacggactac
  1196761 ctggtgcggg cttttgagct gggcataccg gttgaatacg tgcctgacat ggtcgtccat
  1196821 caccaccacg gccgccgcca tcgtgcggca atcgaagagc tccatcgcaa ctacagcctc
  1196881 ggcaatggcg ggctttgtct gaagcacctc cttcgcgcgc cgtggctcct caagcatttc
  1196941 ggctggaccg tcagatccgc gtggggcgag gctttcggcc gttcccgctt cgatccagaa
  1197001 ctccaattgt cacactggcc catcgtttcg atgaacctgc ttggcgcact tcgctttgcg
  1197061 tggcttgccg cggcgaatgc ggaaccgcgg atcgaacggc gacgggtcga acaaccagag
  1197121 ccgaagctca ggtgagggcc attcatgcgt agattcctat tgccaggtct cgaagtcctt
  1197181 cgcggcgcgc tagggcgcca aatgcgcctg cttccggccg tcgtcattct cggccttacc
  1197241 agcgctgcgc tcgaaggcgc cggcatcggg ctcatcatac ctatgctgag catcatcgcc
  1197301 ggagacgagc aggccaccgg cctgagcggc atctccgctt atttccaggg gatgggggag
  1197361 ggccttgatg acggcgagcg cctgttggcg atttcggtag cggtgctggc tctgatcctc
  1197421 ctcaagaacg ttctttcctt cgccaacacg ctgctcacga ccttcatata cggcaaagcc
  1197481 agccactccg tccgcagcgc gctctcggat cagctgctgc ggatcggata ccccttcttc
  1197541 atgcagcata atccgggccg gctgctcaac atcatatcca atgaatcgtg gcgcgcgtcc
  1197601 gacgcgatcc agacggtgct cgccgcgatc gtacatggct cagccgcgct gatccttctc
  1197661 gccttcctgt tgctcatgtc gtggcagatg acgctgttcg ttgcgctcgg ccttgtcctc
  1197721 gtccagcttg cgcatgcggc cctttcggcg acgctcaagg gcccgagccg ccatgtcact
  1197781 tccttcaaca gcgagctttc cgccagaatg ctgcatctgg tgcacgccgg gcggctgatc
  1197841 cgtgtcttcg gtcaggaacc gcgcgagaag caggcattcg attcggcctc ggacgccgtt
  1197901 cgccgggccg gcttcgtgct gcaatcacga cagggtgcgc tgccgccgct caccgaagtt
  1197961 ctccattcgg cgctttttct cgcggtggtg gttagcgcct ggtccgtcgg cgtcagcttt
  1198021 ccggtgatcg tcgccttcgt cgtcctgctt taccgcctgc agccgcatgt gcgcgccctg
  1198081 cagatgtcct ggagccagat ccagggctgg agcgggtcgc tcgaagaggt gcggtggctt
  1198141 ctcgactcgt ccgacaagcc gaagcctccg gagggcaaga ctccggtcga cggcctgcac
  1198201 gagatcttgg tgttcgatcg ggtgaccttc cgttatccag gttccgaggt gcggccagtc
  1198261 gttttacgtt ccgcgagctt cgaaatccgc agcggtcgtt cgacggcgat catcggtcgt
  1198321 tcaggcgcgg gaaagaccac gatcgtcaat cttctgtgcc gtttcgtcga gccggatgaa
  1198381 ggatgcatcc tcgtcgacgg ggtgcctctg agtgagatcg atccgatcca gtggcggcgc
  1198441 cagatcgccg tcgccagcca ggatctcgaa ctggtggacg gcagcattct ggaaaacatc
  1198501 acctatggtc agagcgccac cttcgcggaa gcggaacgcg ccgcgaagct cgccgaggcc
  1198561 cacggcttca tagagcagct gccgcagggc tatcagacag tcgtcggtta caggggggcc
  1198621 agcctctcgg cagggcagag gcagcgcatc gcgcttgcca gggccctcgt gcgcgatccg
  1198681 gcgatcctga tcctagacga ggcaaccaat gcggttgacg gcctgtcgga ggcagcgatc
  1198741 gtcgagacgc tgcgattaag agccggcaga cgcacgacga tcgtgatcag ccatcacagg
  1198801 agcacgatct cgttttgcga cgacctcgtg gtccttggtt ccgggcacgt gaagggtcag
  1198861 gccgcactgg ccgacgtcgc gtcgctcagc atggatcagc tatacgagca tgagacgcgc
  1198921 gcggacagcg caacgtaaac tccccatgtg gccctccgcg agatggggag ttggcttttg
  1198981 catgtcttcc cgaaccgcga tcttacgcgg ccgcgtaacg cttggccatt tccggcaaac
  1199041 gcagcacccg gatcttcgag gcctggccgg cggagcggaa tgcctcgaaa cgctccttgc
  1199101 acacctcggc catgtgggcg atcgccggct tcagatagtt gcgcgggtcg aaattgtccg
  1199161 gatgttcgat atgattcttg cggatctctc cggtaaaggc gaggcggaga tccgtgtcga
  1199221 tgttgacctt gcgcacgccg agcggaatgg ctttctgaat ctcggatacc ggcacgcccc
  1199281 aggttttctt catcttgccg ccataggcat tgaagagttc ctggagaacg gcgggcacgc
  1199341 tcgatgagcc gtgcatgacg aggtgcgtat tcggcaaccg cttgttgatc ttggcgatcg
  1199401 tttcaatcga gaggatttcg ccgtcgggtt cgcgcgtgaa cttgtacgcg ccgtggctgg
  1199461 tgccgatcgc caccgcgagg gcatcgacgc cggtcttcga cacgaagtcg agggcctgct
  1199521 cgggatcggt gagcagttcc tcgcgcgaga gcttgccctc gaagccgtgc ccgtcctcct
  1199581 tgtcgccggc acccgtctcc agattgccga ggcagccgag ttccccctcg acggaaacgc
  1199641 cggccgcatg agcgatcttc acgacttcgg ccgtgacggc gacattgtat tcgtagctcg
  1199701 cgacggtctt gccgtccttc tccagcgagc cgtccatcat cacggaggtg aagccgttga
  1199761 tgatcgccga gatgcaggtc gacggctggt cgccatggtc gaggtggaga cagacgggga
  1199821 tatgcggata ttcttccaca gctccaagga tcagatggcg gagaaaggcg tcgccggcat
  1199881 aagcgcgcgc gccgcggctt gcctgcagga tgacaggaga gtcggtggca tccgcggcgc
  1199941 gcatgaccgc ctggatatat tcgagattgt tcacattgaa ggccggcagc gcgtaattgt
  1200001 tctctgccgc gtggtcgagc agttgccgca atgtgatcaa tgccatcatt aactccctga
  1200061 tgctccgcgc caatcgggcg ccaattcgag gcacaataat tcatgcgggg cttttggcaa
  1200121 ccggcccggc ggtgctgccg gtcgcttgat ggacgtgcgt caggccaaat ttttgtggat
  1200181 gagaaatcat gcagtcagaa ttcgctactt tcgccctctg gtggtgctgc cactctgggt
  1200241 gcgccccgcg gggcggtcgc agcttttcgc cggccgactg ccggctccgg ccccgaagcc
  1200301 cgcgctgggt gtcgggttca ggtgcgtgtg gtgaaggagg accgatttgc aaaaagattg
  1200361 cagcaaggcg gtcacttttt tgtgcatatt acgtaaagtg ccgctacaat tcatgaaggt
  1200421 tgcatgacag cttttttccg gccttcctgt gagaagcgga cgcagcaagg ctgaagcgaa
  1200481 ctacaacgtt gcagtcggac atccgcctct cggctccgcg cggtgcacat gcgccgacga
  1200541 gaagcggaaa ctcattgcag atgctgtgca acctgggcgt ttacaggtgt tcgtctttta
  1200601 aagagaagga tgcaattttc cgaaccgatc agcttgcgtt cgctgagaat ttgcacttct
  1200661 ctccttcgat caatgaaccc aaaaacgagg ggaaggagaa gaaaaatggc tttactcaga
  1200721 cataatctcg ccggcgcggc gctcatctgt tcgctgctca tgggggcaag ccccgcgctc
  1200781 gcccaggcgg tacttcaccg cggcaatgcc ggcgagccgc agacgctcga ccaggctcac
  1200841 acctccatca atatcgagga gttcattctc aaggacctct atgaaggcct gaccatctat
  1200901 gatgccgcgg gaaagatcgt accgggtgcc gccgaaacct gggagctttc ggatgatggt
  1200961 accgtctata ccttcaaact gcgtgccgat gccaagtggt ctgacggctc accggtgacg
  1201021 gcagaagatt tcgccttctc cctccgtcgg gtggaagatc cgaagacggc ggccgagtac
  1201081 gccaatatcc tgttcccgat caagaacgcg gaaaaggtca acaagggcga actgccggtc
  1201141 gaccagctcg gcgtgaaggc cgtcgacgag aagacgctcg aagtcaccct cgaacgtccg
  1201201 acgcctttct tcctggaact gctcgcacat cagacggctc ttccggtcag caaggccaac
  1201261 gtcgagaaga acggtgccga cttcgtgaag ccgggcgtga tggtttcgaa cggggccttc
  1201321 aaactggcgt cacatgtgcc gaacgacagt ctgaccgtgg agaagaacac gaactactgg
  1201381 gatgccgcca acgtcaagct cgacaaggtg atcttctatc cgatcgatga tcaggccgcc
  1201441 tcggtgcgcc gtttcgaagc gaaggaaatg gacctcgcct ataacttctc ggccgaccag
  1201501 atcgaccgcc tgcgtaaatc ctatggtgaa caggtgcacg tttctccgac gcttgcgacc
  1201561 tactactacg ctttcgacac gcgccaggag ccctacaacg atgtccgggt ccgccgggca
  1201621 ctctctatgg cggttgaccg cgacttcctt gccaaggaaa tctacagcgg ctcgcagctg
  1201681 ccgtcctatt cgatggtgcc gccaggcatc gagagctacg gagatcccgc caaggccgat
  1201741 ttcggggaca tgtcgcaact cgaccgcgag gacaaggcga tcgagttgat gaaggaagcc
  1201801 ggctacggcg aaggcggcaa gccgctcaac atcgaaatcc gctacaacac caaccccaac
  1201861 catgagcgtg tcgcgaccgc ggttgccgac atgtggaaga acaccttcgg tgccaaggtc
  1201921 tcgctggtga atctcgatgt gtcgtcccac tacgcctatc tgcaggaagg cggcaagttc
  1201981 aacgtcgcgc gcgcaggctg ggtcgccgat tacgccgatg ccgagaactt tctggcgctg
  1202041 agcctcagca ccaacaagac gttcaattac ggccacttcg aaaatgcgga attcgacgcg
  1202101 ttgatgaaga aatcctatga agaacaggat cctgcagcac gttcgaaaat cctgcatgag
  1202161 gccgaaacgc tgctgatgaa ggaacagccg atagcgcccc tcctgaccca ggccgacctc
  1202221 tggctcgttt cggaacgggt ccagggttgg gtggacaatg cgccgaacgc tcacctgagc
  1202281 aagttcctga gcatcgccga gtaacgaaca gaggcgacgc gcgggcatct gcgcgtcgcc
  1202341 tccggagcca aatccatgat ctctttcatc cttcgccggc tggcgagtgc ggtgccgacg
  1202401 ctgtttatcg tcgtcacgat atccttcttc ctgatgcgat tcgcccccgg cgggcccttc
  1202461 aacctcgagc gtcctcttcc gccctccacg atggagaatc tgatgaggac ctatcacctc
  1202521 gaccagccgc tctggcgcca atacgttcac tatctgagca atgcagtcac cggcgacttc
  1202581 ggcccgagct acatttacca cgacaacaat gtcgcgcagc tgatcggcaa aggtctgccc
  1202641 tattcgatgg agcttggctt ctacgcgctg ttgctggcag tcgtcggcgg cgtcataacg
  1202701 ggaacgatcg cggctttgaa gcagaacagc ttcctggatt tcgcggtcat gtcggtgtcc
  1202761 accatcgggg taaccgttcc gaacttcgtc gtcggccccg tgctcacgct gatcttcgcg
  1202821 atcatgctcg cgtggctgcc cgccggcggc tggggcgatg gatctttgcg ttttctcatc
  1202881 ctgccgatga tcgcgctggc gcttccccag cttgccgtct tcgcaaggct cacgcgcggc
  1202941 tcgatgatcg aggcgctcca cacggatcat atccgtacgg cgaaggccta tggcctgccg
  1203001 tcccgcgccg tcgtcgtgac gcacgcgatg cggggagcca tgctgccggt cgtctcctat
  1203061 ctcgctccgt gtgctgccgc cctgcttacg ggttcggccg tggtggagac gattttcacc
  1203121 attccaggcg tcgggcgcta cttcgttctt ggcgcgatca accgcgacta tacgcttgtg
  1203181 atgggtaccg tgatcctcat cgccatcttc gtcatcctct tcaaccttct ggtcgatatt
  1203241 ctctacggcc tgctcgatcc gagggttcgc catgactgat attgctcaga tcccggcatc
  1203301 ggcgcccgaa accagggggc gcagcctgtt tcagctcgcg gcgctgcgtt tccgccggaa
  1203361 ccgccccgcc atggcgggct gcgtcatgct ggttctcatc ggcctctttt ccttcgtagg
  1203421 gccgcttttt tctccccata gctacgatca ggtgtttccg tcctatgtca cgatcgggcc
  1203481 aagcctcgag ccgcgaccgg atagttcgac gcttcaggac gtgatggaag gcgtggcgtc
  1203541 ccgtgcccgc gtcaggctga cggaattcgc cgtcgaggat cagagcttca ccgccacggt
  1203601 cacgtcggat gcgccgatcg atccccgcgc cacgcgctat ttcgaccggg cgaacgagtt
  1203661 cgagaacacc aaggtggtcg caacggaggg cgatggccga acgctgaagg tcgagggcga
  1203721 cgtggctcgc gaatatttcc ccttcggtac cgattcaaac ggccgcgatc tgcttgtccg
  1203781 ggtcatgctg ggcgggcaga tctccatcgc cgtcggcctg ctggcgagcc tcgtttcact
  1203841 cggcatcggt gtgctttacg gcgcgacttc cggctatatc ggcgggcgcg tcgacaacgt
  1203901 catgatgcgt ttcgtcgaga ttctctattc gctgcccttc gtcttcctcg tcgtggtgct
  1203961 cgtcgtcttc ttcggccgca gcttcatcct gatcttcctg gtaatcggtg cagtcgagtg
  1204021 gctggacatg gcacgcatcg tccgcggcca gacgctggcc ctcaaacgcc gtgagttcgt
  1204081 tggtgcagca caggcgctgg gtctgaccga ctggcagatc atccgccggc acatcatccc
  1204141 caacacgatc gggccggtca tcgtcttcgt caccgtcgtc gtgccgaagg tcattctgct
  1204201 ggagagcttc ctgtcattcc tcgggctggg tgtccaggcg ccgctcacga gttggggcgc
  1204261 gttgatctcg gagggtgcga acaacattca gtcggctccc tggctgctta ttttccccgc
  1204321 catcttcttc gtcctgacgt tgttttcgct gaactttgtc ggcgacggcc tgcgcgacgc
  1204381 acttgacccg aaggaccgct gacatgacag agatgcaaga cgccattctc gcggtccgtg
  1204441 gtctcaaggt cgatttctcg acgcccgatg ggaccgtcga agcggtaaag ggaatcgatc
  1204501 tcgacgtccg ttccggcgag actctcgccg tcgtcggcga atccggctcg ggcaaaagcc
  1204561 aaaccatgat gggtatcatg ggcctgctcg ccaacaacgg aacggtgacc ggctcggcgc
  1204621 tttaccgcgg ccaggagctc gtgggtcttc cgccgaaggc cctgaacaga gtgcgcggct
  1204681 cgaagatcac gatgatcttc caggagccga tgacctcgct cgatccgctc tacacgatcg
  1204741 gtcgccagat cgccgagccg atcgtccatc accgcggcgg tacgttcaag ggtgcgcgca
  1204801 agcgcgttct cgaactcctg gagctcgtcg gcattcccga agcgcagcgc cgcatcgaca
  1204861 gctacccgca tgagctctcc ggcggtcagc gtcagcgcgt catgatcgcc atggcgcttg
  1204921 ccaacgagcc ggatatcctg attgccgacg aaccgacgac cgccctggac gtgaccatcc
  1204981 aggcccagat cctcgatttg ctcaaggcgc tgcaaacgcg tttcggcatg gccatcgtgc
  1205041 tgatcacgca cgaccttggg attgtcaaac acttcgccga gcgggtcgcg gtcatgcgcc
  1205101 gcggcgaggt tgtggagcag ggcacgacgg ccgacatctt cgagcggccg gaggcggact
  1205161 acaccagaat gctgctggag gcagagccga gcggacacaa ggctccgccc ccggacaatg
  1205221 caccgatcat cctcgagggg cgcaatgtcg gggtcgacta tacgatcccc ggcggcctct
  1205281 tccggggcgc ctcgaccgcc ttccgggccg tcgacggcgt aagcctgagg ctcaggcaag
  1205341 gccagacgat cggcattgtc ggcgaatccg gttcgggtaa gtcgacgctc ggacgggcgc
  1205401 tgctgaggct tttgccgagt agcggttact atcgctttgg ttccacggat atttcgggat
  1205461 ttgaccgcgg cgcgatgcgg ccactgcgcc gccagctgca gctcgtattt caggatcctt
  1205521 acggatcgct ctcgccgcgc cggaccgtcg gcgagatcat taccgaaggc cttcatgtgc
  1205581 atgagcccga cttgagccgc gccgaccgcg accggcgggc catcgccgca ctgaaggagg
  1205641 tcggcctcga tcccgcctcg cgcaaccgct atccgcatga attctccggc ggccagcgcc
  1205701 agcgcatcgc aattgcccgc gcgattatcc tgaaacccaa ggtcgtcatt ctcgatgaac
  1205761 cgacctcagc cctcgatcga tcggtacagg ggcaggtgat cgcactcctg cgcgatctgc
  1205821 aggagaagca cggtctttcc tacatcttca tcagccacga tctgtcagtc gtgaaggcga
  1205881 tgtccgacta tgtgatcgtg atgaaaaacg gccgcatcgt cgaagagggg gaaactgacg
  1205941 cgattttcaa ggcgccgcgg gagccctaca cgaagacgct gatcggcgcg gcattcaacg
  1206001 tgtgagggaa cggcgggtgg cgcttcctct catccgcatt gcggcagctt ctccccgcag
  1206061 gcgggcgaag gggaactcgc ggcgccgctt gagccacttt caccgccttc cttctcgcgg
  1206121 agaacggcac ggctcccacc aacgcgaagc cctaccgctc ctcagtcaaa gccttcttgt
  1206181 cgagcccgaa cttctgcatc ttctcgtaaa gcgtcttgcg cgagataccg agcgactcgt
  1206241 aaacgggttt caatgctcca ccgtgggcgg ccagcgcgct ggcgatcacg cttctttcga
  1206301 aggcggccac cttttcggcg aggcgctgcc cattcgcagg agcgagcgct tcttcgcttt
  1206361 cgggttcgag accgaggatc aaacgctcgg cggcattgcg cagctcacgc acattgcccg
  1206421 gccattcgcg tgaagccatg tccgatgcga gcgccgccga tatctcgaca tcgtcccggc
  1206481 cgtatcgggc ggcggattcg cggacgagct gcatgaagag caaggggatg tcggagcggc
  1206541 gctgcgacag cgtaggcact ctcaaagttg cgacattcag ccggtaaagc agatcggcac
  1206601 ggaatcggcc atttgcgacc tcgcgctcca aatcgacctt gctggtggcg atgaagcgaa
  1206661 cgtccagtga aacggtctcg ttcgagccga gacgggttat gacacgctcc tgcaggacgc
  1206721 gaaggaactt tgcctgaaga tcgaaaggca tggagccgat ctcgtcgagc aggatggtgc
  1206781 cgccgcggcc atgttcgaat ttgccgtaac ggggcctgag cgctccgggg aatgcgcccg
  1206841 gctcgtggcc aaagagttcg ctctcgatca gattctgagg aagtgccgca caattgatgg
  1206901 cgatgaacgg gcccctcgcg cggctgctca aatcatgaag cgcacgggcg acgacttcct
  1206961 ttccgacgcc ggtctcgcca atgatcagcg tgtcggcgtc agaggcgccg atcgccctga
  1207021 cccggtagcg cagatccacc atcgcttggc tccgccccgg cagcctttgt tctatgtcgt
  1207081 cgcgcttccc cgcgacagcc cgcaaccggc ggttctcgag cacgagagcg cgccaatcga
  1207141 gcgcgcggcg tatggtgccg gcgagcatct gggcggtgaa aggcttttcg acgaaatcat
  1207201 aggcaccctc acgcatcgcc cgaaccgcca gctggacatc gccgtgaccg gtcaccagga
  1207261 tcaccggcag ttcggcatcg atctcgcgga tgcgctgcag aaaggtcatt ccatccatcc
  1207321 cgggcattcg gatgtcgctg atgaccaccc cgtggaagct gaaggcgatg cgctcgagcg
  1207381 cgtcttcggc acaggcgaag gtatccaccc gaaaccccgc aagctccagt gcctgagcgc
  1207441 tggaacggcg caattcctct tcatcatcga cgagcaggat gcggctttcg ctcattcggc
  1207501 tgcctcgcga ccggtttggc cggcgagggc gagctcgatg cgaaagaccg ctccaccctc
  1207561 cggatggttc gacacggtca ggctgcctcc gaaatccttg atgatgttgt aggaaatgga
  1207621 caggccgagg ccaagacccc tgccgacgcc cttcgtcgtg tagaatggat cgaaaatgcg
  1207681 ctcggcgacc gacggcgcga cgcccccgcc gcggtcgcgc acggtcagca cggctttgcc
  1207741 gtcctcgcgc catgcgcgca cggagagcgt gcggtcgtcc agcccctcaa cggcgtcggc
  1207801 ggcattggat atcacgttga cgagcacctg ctgcagccgg accgaaccag cccggaccat
  1207861 aaggtccccg tcaagctcaa tgtccatctt tgcgcccgcc gtcttgattc gtgctgccac
  1207921 gatctcgagc gtgtcatgca ttacctcgtc gagacgaacc gggccgagct tctcattggg
  1207981 ttttcgggca aagttgcgca gatgccggct gatcgatgcc atgcgatcga tcaggcccga
  1208041 aatgcgcctc acattgtcgc tcgcctcggc ggttcggccg cgctcgatca gcagtgcagc
  1208101 gctgtcggcg taggtcttgg cggcggcaag cggctggttg aattcgtgcg acagggccgc
  1208161 tgacatctgc ccgagaccgg cgagtttgcc cgcctggatg aggtcggcct gggtttgccg
  1208221 caactgctgc tcggtgagcc gccgctcggc gatttcagcc tcgatctgcg tgttgacgcg
  1208281 cgcgagatcc gccgtgcgtt cttcgacccg gcgctccagc tcttcctgtg cctgctcctg
  1208341 catcaggatg cgttccctga gccgcgcacg gcgttggatg aaaatcgcga tcgcaagccc
  1208401 ggtcaggcag agcagcagca ggacggcggc aaccgtggtc aaggcttgcg tgcgaacgga
  1208461 gcccgtgtcg gcgagcacgt tcacggtcca atcggcctcg ggcatatagt gcgagaggac
  1208521 gagatattcc cggtcgctgc ccccggagac ccttaacacc cgatgtccgg atagttcact
  1208581 ttgcacggcc ggcaactgat gcagaacggc atcggcatag cgccgcgatg cttccgtcct
  1208641 ggcaagccgc tcagcggtca ggggcaggat cccggcgtag agccattcgg gattgccgct
  1208701 catgaagatg ataccctccg ggtcggacac aaagatcctg tattcgccgc cttgccagga
  1208761 ggcttcgatc gtctctatgt ccaccttgaa cacgatcacg ccccggatgt ctccgccgat
  1208821 gcggacagga gcgccgaagt agtagccgcg ctttagcgat gtcgtgccga gcgcgtagaa
  1208881 gcgagattgc tcgcccttga gcgcatcctg gaaatagggc cggtagctga aattctctcc
  1208941 gacaaagctc gtcggtccat cgtagttgct cgcggcgatc gtattgccgt tcggcaggat
  1209001 cacgtaaatg tcggaggact tgagaagtcc attgatctct ttcagatagg aattgacggt
  1209061 gccgcgcagc tccccatcgt tcggacgcgt caccagctcc ttgacgtcgt catggtcggc
  1209121 gatgagcgcg ggcagggcct gatagcggtt caaatggccg ctaagagcgg ccaccgccag
  1209181 tcgcagcgcc gtgtgtgcct gcgaggaggc ctcctgcata tagctgcgcg tggcgacggc
  1209241 gtttccctgc acggcgatta acccggcggc tgccggcacc agaaggagtg cgagaaagaa
  1209301 gcggtatttc acggaatgcc cgggctcctc ctcccgctcg cggtcttggc tgcaggttcc
  1209361 tttttgcgcg gccgctgcca cgcgatgcta attgtcggtc tgacgcgttg caagccgccc
  1209421 atgcgggtgc cttactccat ctgctctatg acgtagttgt tgacagcggg tcacttctgt
  1209481 caacgtagcg ttgacaatgc atctgtgtgg gatggtcttc cgctctcgcc gcccagggag
  1209541 catctattcg ccatcgacgc tcccgccaaa gctgcgggaa gaaaggaagc cgatcatgct
  1209601 cgaacagatc aaaggcctgc atcacgtaac atccatggca gaggacgctc gtacgaacaa
  1209661 ccagttcttt acccaaacgc ttggtctacg ccgcgtcaag aaaacggtga acttcgactc
  1209721 gccggatgtc taccacctct actatggcga cgagaccggc acagccggca cggtgatgac
  1209781 ctacttccct tttccggaga tgccgcgcgg tcgtgcgggc acgggagagg tggggacgac
  1209841 ggcattctct gtcccgcaag gctcgctagg cttctgggag ggccgtttga cgcgcctcgg
  1209901 tgtgagtggc ctcaagcgct cggaaagctt cggtgagaag cggttgaatt ttgccgggcc
  1209961 ggacggcgac ggtttcgctc tggtcgaggt cagggatgac ccgcgcacgc cctggaccga
  1210021 gggtggcctt tccggggatt acgccattcg cggcttccac tcggtcgcca tgcggttgcg
  1210081 tgacgagggc gccacggccg acctgctgaa gtacatgggt tacgaggaac tcgatcgaag
  1210141 ggacggtgtc acgaggctgg tcgtccccga cggcaacggc gcgaacctcg tagacctcga
  1210201 aacactgccc ggcatcaatc gtgctgcaca gggtgccggt tcggtgcacc acgtcgcatt
  1210261 tgccgtcgac aatcgggagc ggcaactcga gatccgcaag gcgctaatgg ataccggcta
  1210321 tcatgtgacg ccggtcatcg accgggatta tttctgggcg atctatttcc gcacacccgg
  1210381 tggcgttctc ttcgagatcg ccacgaatga gccgggcttc gaccgcgacg aggacaccgc
  1210441 gcatctgggc gaggcgctga agcttccgca gcagcacaag cacctgcggc cgattctcga
  1210501 aggtcattta cagaggctgg aagcgtaagc ggacgcgtct gccgcttcag cccggccttc
  1210561 tcggtacgcc gggaagggtt caatattcca atattcacag ctgaacgcgt gttggcaagc
  1210621 aagcgcgcat gatggagaaa tcgatgcctg atcacggtta catgcataaa ttgaaagccg
  1210681 gcagtcccgg cggacccatc cttttcgttt ttcacgggac cggcggcgac gagaaccagt
  1210741 tcttcgactt cggagcacag ctcctgccga aagccacggt ggtttcacca aggggcgacg
  1210801 tgtcggagca tggagccgcc cgctttttcc ggcgaacggg cgagggcgtc tacgacatgg
  1210861 cggatctagc acgtgcgact gagaagatgg cgggtttcgt gaaggcgctc gcaagcgaat
  1210921 acgaggcctc ggagatcatc ggtctcggct actccaacgg tgccaacatc cttgcgaatg
  1210981 tccttatcga agagggtctc ttcgataagg ccgtgctcat gcacccgctg atccctttcc
  1211041 gcccgaaggc caatgccgcg ctcgccggtc ggaaaatcct gatcactgcc ggagaacgcg
  1211101 acccgatctg cccggccccg ctgacacaag cgctgggcga ttacctctcg cagcagaacg
  1211161 cggcggtgga actgaagtgg cattcgggtg gccacgacat ccgccagaat gagatcgccg
  1211221 ccactgaaga gtttttgaga gtctgaagcg agaagcaacg cagtagcttt gaaacgacgg
  1211281 gtgaagtcag ctaagttcaa tgaactaagg ttgaacccga ggccttgata gaaaccgtca
  1211341 acattcacca agcgaaaacc aatttatcgc gtctgatcga aaaggcggct aagggagaac
  1211401 ccttcatcat cgccaaggcg ggaaaaccga tggtgaaggt gatcccgctc gatcagccgt
  1211461 ccgatgcgaa ggtgcagcgg atcggcttca tggcaggaca gttttcggtg ccggacgatt
  1211521 tcgatcggat gggccgtgac gagatcgaag gtcttttcgg cgcatgacta ttctttgata
  1211581 cgcacattct cctctgggca gccggtgtac ccggccgctt gtcgaatgag gcccgtgctc
  1211641 tcatcgaagg ccccgggaat acgctcgact tcagcgcggc gagcgtgtgg gagatcgcga
  1211701 tcaaacgtgg cttgggccgg atggatttcg atgccgatcc acggcttctg cgtcgaggtt
  1211761 tgctggacaa tggctaccag gaattacggg tagagggcac ccatgcggtg gcacttgatc
  1211821 aactgccccc gatccatcag gaaccgttcg accgcattgc gatcgcgcag tctctcgtcg
  1211881 aaggatttac gctcgtcacg tccgatgaag ttgttagccg ctaccccggt cctagccggg
  1211941 ttgtttagtc ttcattcgag acgcttgcga aagagccacg ccgccgatga cagagtgacg
  1212001 atcgcgatca ggcaaagggg aagcgtctgg tggacgactt cgtaaagcgg gatgtccttg
  1212061 aggaacacgc cctttacgat caccaggaaa taacgcagcg gattgatcag cgtcaccggc
  1212121 tgcagccagg agggcatgtt ttcgatcggc gtcgcaaatc ccgaaagaag catggcgggc
  1212181 accatgaaga gaaaggcccc gaggatcgcc tgctgctggg tcttggacag tgccgagatg
  1212241 aagagaccga gaccgacgac ggcggcgaga tagaagacgg cgctgccata gagcaggaaa
  1212301 agcgaaccgc gcagcggcac gccgaacacg aaaaccgctg caagaatgta tatggtgatg
  1212361 tggaagagcc cgatcatcat aggcgggatg agctttccaa gcaaaatctc gtgggtgcgc
  1212421 aacggcgaga cgatgagctg gtcgaaggta ccgagttccc gctcgcgtgc cacagatagt
  1212481 gccgtgacga tcagtccgat caggagagcg atgctcgcga ccaggttcgg caccatgaac
  1212541 cattgatagg tcaggttggg gttgaaccag ttgcgggcaa cgacctggac cgtttcggag
  1212601 ggcgcgcgct tgccggccgg cgtttcggct gcgagcgtgc tgacgatacg cccgagatag
  1212661 ccggacacga tctgcgacgc attggagcgc cggccgtcga ggatcagctg cacctcagcc
  1212721 ggtcttcctg cctcaatgtc gcgggagaag gtggggccga tctccacagc ggcgatgaca
  1212781 cgctgcgtat cgatcgccag acggacctcg gcggggctgc ttgcaagctc gatcgagcga
  1212841 aatgtcggag agccgccgac cagctggatg agttcctggc tccactggcc attgtctcgg
  1212901 ttcagcacca tgatgtcgac atctgtcacc tcgagcgtcg ccgcatagga gaagacgagg
  1212961 agctggatga tcggagggcc gattagaatg gtgcgcccct tcggatcacg aagaaccgcc
  1213021 agcagctcct tgacgatcag cgccttcagc cgtgtccacc acatgtcagc cgatcctctt
  1213081 tctagtgctg cgcgcggcaa gcgcgaagaa catgcagccg atcaggaaca tgaccgcgat
  1213141 ggcgcgtgcg aacatcggcc agatgtcccc ggccagaaag acagtctgaa ggctgggtat
  1213201 gaggtagctt gccggcactg cataggtgat ccattgaatg acggtgggca tggaattgat
  1213261 ctcgaaaaga aaaccggaca gcagaaaggc cggcagaaag gccgagatca gcgcaagctg
  1213321 ggaggcaagg aactggttct tcgtcgcggc cgagatcagc agcccctgtc cgagagccgg
  1213381 catgaggaag gtcgccgaaa gagcgtagag cgcagctacc gaaccgcgga aggggacatc
  1213441 gaagacaaag acggcaagca gaacacaaag cgtcatcgat gtaagaccga ggacaaagta
  1213501 gggcaagagc ttgccggcga gcagttcggc ggcggaaacg ggcgtcgcca tcattgcctc
  1213561 catcgtgccg cgttcccatt cacgtgcaac gacaagcgag gtgaggagcg tgccgacaag
  1213621 agtcatcacg atggcgatcg accccggaac caggaagttg cggctcgtca gctgcgggtt
  1213681 gaaccagaaa cgctgctcgg tggagattgc cgggggcatg ctcctgcctt cgctcatgcg
  1213741 ctgacgctcc cagttggcaa cggtgccttg tgcatagttc tgcacgaaat ttgcggtgtt
  1213801 cggatcggag ccatcgacaa tcacctggac cgacggatgg cgtgccgccg cgtgatcggc
  1213861 ggcaaagccc gccgggatca ccactatgcc gcgcacatgg ccaagcacga gctcgtcttc
  1213921 gaattccctg cggtcgcgtc ccgcgaccac ggagaagtag cgcgaggcct caaagctcgc
  1213981 agcaagatcg cgggtgagcg ggctggtctc ttcgacgacg agggccacac gcgttcgtgt
  1214041 cgtgtcgagc gacacgccgt aaccgaagag aaagagaagg accaagggca agacgaaggc
  1214101 tatcaggata ctgctcggat cgcgcacgac ctgataactt tccttgcgaa cgagggcagc
  1214161 gaagcggcgg gcgcgtccag agcttttgta agcctgtgcc tttttccctt ggtccttcat
  1214221 gctgcgtcct tcgcctccga gccctggacg agggctatga atgcgtcctc cattgtcggg
  1214281 tcgggaaggt cctcgctcgc gatgcgggcc ttcatttcgt cgggtgagcc aagcgcgatc
  1214341 gaacggccgc gataaatgag cgatatgcgg tcgcaatact ccgcctcatc catgaagtgc
  1214401 gtggtgacga gtacggtcac gcctttttct acgaggccat tgatgtgggt ccagaactcc
  1214461 cgccgggtga tcggatcgac tccggaggtc ggctcgtcga gaaagagcac ttccggttcg
  1214521 tgcaagaccg cgcatgcgag cgccaggcgc tgcttgacgc cgagcggcag atccttggcc
  1214581 gacatgtcga gcacgctgcg gaaatcgaag atctctccca taagcgcgat gcgctcgcgc
  1214641 tttcgcgcac cggcaagtcc gtaaacgccg gcaaaaaaat tcaggttctg gatgacgctc
  1214701 agatcgccgt ataaggagaa cttctgcgcc atgtagccca gccgattacg tgccgccggc
  1214761 gcatcgcgcc tgagatcgaa gccggcgacg cggccgtcgc cagcggtcgg cgtcagaaga
  1214821 ccgcacaaca tcttgaaggt tgtcgatttg ccggcgccgt tcggaccgag gaggccgaaa
  1214881 atttcgccgc gcggtatgtc gaaagtgatg ttgtctgcgg cggtaaaatc gccgaaccgc
  1214941 ttcgtcagcc cacgtgcctc tatcacggat ctgccgtctt ctgaggcgaa ggcgcgctgt
  1215001 gtttccgcaa gcctcgaccg tccgccgggg ccgccaccga gcatatcgac gaacgcgtct
  1215061 tcgaagcgcg gcggcgtgac tgccgcgcaa tacgcgccgg tcgcctctct ggactgaaat
  1215121 ggttgaaggc ccggcttcat gacaagacgt atggcttcgc cctggatcac cccgtcgacg
  1215181 acgccttcca tttcgagaaa atgcgcaagc ttttcgcgcc ggcgtccacg gatgccggag
  1215241 aggcggaaga cccggttctc gacgcggccg gtcatctcgg ccggcggacc ggaaaacaat
  1215301 agccttccct ggttgagcag aaagacatga tcgcaggctt ctgcttcttc caggtaggcg
  1215361 gtcgaccaga cgacgccgat gccttccgcc ttcaaattct cgaccatctt ccagaggtcg
  1215421 cgccgtgaaa tcggatcgac accgacgccg ggctcgtcga gcaacaggag ccgcggcttg
  1215481 cgaaggagcg cgcaagccag cccgagcttc tgtttcatgc cgcccgagag cttgccggcg
  1215541 agccgggtgg taaaccgggc aagatccgtg aactcgagca actcgccgaa ggtgcggctc
  1215601 cgctcggact tgggcagacc gcgcagatcg gcgtaaaggt cgagattctc ctgaaccgac
  1215661 aagtcttcgt agaggccgaa ccgctgcggc atatagccga tggacgcctg aatgccggcg
  1215721 ggatccgagc gggtatcgta accaagcact tcgacgctgc ccgcatccgg cagcatcaga
  1215781 gctgtcatca gccggatcag cgtcgtcttg cccgccccat ctgggccgac gatgccggtg
  1215841 atccttccac ccaggatatc gcccgcaacc gcgtctaaag caggggccgc tgaaccgaat
  1215901 cgcttggtga cagaggtgag cctcacaaac ggggtcgtgt cgagcgccgt tgccatggcg
  1215961 gtcatcagga cgcttccttc gtttccggca gctgcacggt gaccggcatg ccctggcgaa
  1216021 gatccttgcc gggattggtg atgacgatcc tcaggcggta gacgaggtcg gttctgagct
  1216081 cgggcgtctc caccgatttc ggcgtgaact ctgcgaccgg ggaaatgaac ccgacggtgc
  1216141 cctcataggc gcgaccgggc gccgtgtcgg aggcgatcgt caccttcatc cccggataga
  1216201 gacggccgag atcgggctct gcgacatagg cgcggaccca gacgggttct gtcagcgaaa
  1216261 gtacgtagac gacatccgct ggtgagacga tcgcgcctgt ttcccgcaca cgcgagagca
  1216321 cgacgccgtc gttcggggcg acgagctctg tgtccttgag cgaggtgcgg gcgctcgcag
  1216381 cctttgccgc tgcggcgtcc acctgagcct cggccgatgt tatatcctcg acacggcttc
  1216441 cctcttcgag gagtgccaga ccttcgcggg cggaccttgc gcgcgctgct gccgctgcgc
  1216501 ggcctgcgct tgactggtct aactccgcct gtgagatcgt gccgttcgga cggagctgct
  1216561 tcgcgcgctc ataagcaagc tccgcatttt cgagctcggc gaggcgttcc tcgtgggtgg
  1216621 cgcgcgcctg agcgatttcg ccggcgcgcg cgccggcctt gagctttgtc agggtcgccc
  1216681 gggaagcctc ggcttccgct tcggacgcat cgagcgtctg tcggaatggc tcgtcatcga
  1216741 gcctggcaat gacgtccccc ttcctaacgc tatcaccctc gtccacgcgc aactcggcga
  1216801 tgcgcccgct cacccgaaaa ccgagcgata cctgacgaat gtcgacattg ccgtagagca
  1216861 ccgcctgccg cgtctcgccg gcaaagccga ggcgaaccgg aagatcgaac caccatgccc
  1216921 cggcgacggc cgcggcgagg attacaacga tcaaggcgat ctttttcatg aacggcggtc
  1216981 cttttcggca ccgagcaccg ccacgagttc gacggcatgc cggtgcagtg tctcgatctc
  1217041 cttcggtccg gcggtctccc attcgagttg ggcatagacg gccgcatgcg ccattcggaa
  1217101 caccagaatg cttccgacga aggagagggt cctcagacgg atgtgctcag aggccgggtc
  1217161 gtcgtggaga atggcgccga tcagccgccg cgccatttcg atcatcggcc ccataatgct
  1217221 gccgtagatg cgcctgaagg cctcggtcgg ctccatctgc tcgcgaatga tgaagcgcgc
  1217281 ccagctttcc gactgtttgc tgacgaagag gatgatcatc cgctggacca tctgggtcag
  1217341 gaagtggcgc gcctccgcgg atgtcaactg cgcgcccgct gcgtcgagtt cggctatgcg
  1217401 cgagacgatc gtgctgcgca ggtcgccgac atgcccgccg atcgccgagg cgaggtgctc
  1217461 ggcggccgct atataaagcc cttccttgcc gccgaaataa taggggatcg cctgaaggtt
  1217521 gacgcccgct gcgtcggcga gctttcgcgt cgtcgcgcca tcgaagccgt atcgtccaaa
  1217581 gacgtcgatt gcaatgatga gcagtttctc ccgcgtcgca tcgccgcggt cgcctctagg
  1217641 tattgtgggt cggttggcgt cctttttcat gcctggagaa tgcaccattc gatcgaatga
  1217701 gtcaatcgat cgaatgaaaa agctggcaat ccggtacgaa tgggtacatt ggccgtcttt
  1217761 ggcggtgcag tgcgaaccgg atgggttgga aaagcctcgc aagggccttg ccgaaaatct
  1217821 acaataatga gtttgaattt cgaggaagga actcaatgcg ctttatcaat cccatccctt
  1217881 tcgtgcgcga cataagccga tcgaaggaat tctatcggga catactcggt ataaaggtgc
  1217941 tgaaggattt tggagacttc gttctctttg aaaccggttt cgccatccac gctggaagct
  1218001 cgctcgaaag aacagtttgg cggatggctt caaagtcgga agaatcctac ggccgaagaa
  1218061 atttgctctt gtatttcgaa catgacgacg ttgaggcggc cttcgaaaac atcgcccgac
  1218121 acgtggaatt gatacatccc attgagcggc aagcatgggg ccagcgagtg ttccgtttct
  1218181 atgatccgga cgggcacgcg atagaagttg gtgagccgca agatctcggc ggtttgcacg
  1218241 gttcctgaaa atctcggtga ttattcgctc gcctgggttc ggcggatacc tccgccgggc
  1218301 aagctgttgg cgctccgcca aatctggtag actgaaggcg ccaccgcatc cgcgcccggc
  1218361 ggggcgtgca ttagagggag aagccgatgc agatcgcggg aattcaggtc tatcccgagc
  1218421 gcggcgggaa ggcgggcttc accatcgaat tcgttggcgc caacggcgag gtcatctccg
  1218481 tctcctgtcc gcaaaacgcc gaaggcagcc tgaacaggct gaatgccgtt gccagggcaa
  1218541 aggagatact ctccgcagca atcgatgcgg atgaaacact tctcgccatc accgggacga
  1218601 aacggtctcc gtccgtccct gaaggcgcgc ttgcgaacgc ccggcaatca cacgaccagt
  1218661 atgctatgga agagcagttg gaagagggcc tcgaagatac gtttcccgca agcgatccgg
  1218721 tctcgattac cagttcggcg attccgaagg gttcgtctgg ccgctagacc cgacgaatag
  1218781 cggtcgaagc ttgatggggg cggctgttca agccatttag gagggcgcgc tttcgagtgg
  1218841 aaacccattc ctgacggctg ccgaatccgt tagagctttt ctcggatata ccggtgcggc
  1218901 caccgacggc cgattctgtc aaacagcgaa aggagcacgc cgtcttggac gagcaaagga
  1218961 gaagcgattc atgaatggcc ggcgtctcac ctttgccgtc ggagacattc acgggtgcct
  1219021 cgcacaactc gagaccttgc tggccagtat tgaatcgatc gccgccggcg gcagggtgat
  1219081 cttcctcggc gatcttgtcg atcgcggccc ggatagccgc ggggtcgtcg agcgcatcat
  1219141 ggccgggccg cgtacaacgg gctggaagtg gataacgctc aagggcaacc acgaagccat
  1219201 gctggtggcg gcgcgcaagg gccggcccga gatgtctctt tggctgatca acggcggcga
  1219261 ggagacgatg gcctcttatg ggggtgccat tcccttgagc catctggtct ggatggcaga
  1219321 actgccatcg atcatcatcg agcgccatcg cattttcgtc catgcaggcg tggacgagaa
  1219381 tattcctctc gacgaacagg gcgatgatat tctcctctgg atgcgcaccg atccgaacta
  1219441 ttccggcacc tattggggca ggcatgtctg tcacgggcat acgccgagcc ggagcaatcc
  1219501 gcgcactgtc ggcaacagga ccaatgtcga ttccggcgcg gtcttcggcg gcatgctgtc
  1219561 ctgcgccgtc ttcgacgacg accgggcggg aggaccgatc gactttctgg taacggacgg
  1219621 atacggctag ggcactgcac gccttcgccc ccctcccgtt ggctaccttg ctacctgaat
  1219681 tgggtaatgc tgtgtggggc cataaaaccc ccgctgaagc attgtgccgc accgcttcag
  1219741 gcgatagttg tgccgaccta gaaagcatat gaactcaaat ccaaaggacc cggtttggat
  1219801 acctcctcct ccgcaatctt cacaaagaat ttcgccgccc tccttttcga tatggacggc
  1219861 acactcctca actcgatggc agtcgttgaa agggtctggg gatcctgggc agcccgcaac
  1219921 ggcatcgacc cggtggcgct catgaaggtc gtccatgggg tgcgagccgt cgatacgatc
  1219981 cgcgcactgg gcctgtcggt cgatccggaa caggaggcgc gtattcttgc cgaggcggag
  1220041 atcgcggacg tggacgggat cgtcgaaatc cccggggcgg tgaccttcct gaagacgctg
  1220101 ccaccggaga agtgggcgat cgtaacctcc gcaccgctgg aactggcagc gcgcaggctg
  1220161 gaggcggctg gaatcccggt accacgccta atggtgacag gcgaggatgt cacggtcggg
  1220221 aagccggatc cgcagggcta cctgcttgct gccgagcggc tcggagttcg tgctgaggat
  1220281 tgcctcgtct tcgaagacgc gcccgcaggc gttctcgctg gcaaatccgc gggcgccgag
  1220341 gtggccgtca tcaccggagc ccatgcggcg gcggccgaac tgccgcatgt catgcttgcg
  1220401 cattacagcg atgtcgaggc acgtctcgtg gaggacggct ggctttcgct gcatcggcgc
  1220461 cgcggctgac gcgggcagac tcgtgtgcca attaggtcta gagcgggacc cagaggccga
  1220521 gctggcaata tggccaaccc acccctatac ggcttcgagc gtggcgacgc gggcgcgcga
  1220581 catccggctt tcaagctcct cgaggcgacg ggcgaacccg gcattggtcg gctgaagtgc
  1220641 taccgcctgg gcaagcatcg cacgcgcgac cgaaagctcg ccgtcccgga tgtggcggtt
  1220701 ggcccgatgg tagaggaagt tgacccgctc gacaagcgaa aagccatgcc cgaagcgttg
  1220761 aaggaaccgg tcggcccagg ctggatggcg cgctatcgcg gcaaccgcga tctgataggg
  1220821 gcgcatggtg gcaccgacac gggccgagcg tgccagcgct ttcaaaccgg cccggtcatc
  1220881 attccggcag gcctctatga gcgatagcgc gcgtgccgtg ccggcgaacg ctcggaccgt
  1220941 tccgtgtccg gtcatgtgga cggggatcag atgggtgtct tcctggatcg cggcgatccg
  1221001 ctccgcatgc cggcgatcca cggtgtggaa aggatcgtag aacaggtagg cgcgcccggc
  1221061 cgcctgatcc gcggcaattc ccattttccc gtgcaggtct gccgcaaagt ggcggatgaa
  1221121 gcgattgtcg aatggcacgg cctttggatc gatcgagatc tggggacaga aggctatagc
  1221181 gacggctgcg ccgaaacgcc gacggtatcg cagcgccgcg taaccaccct gcgagtggcc
  1221241 ataaagaatt cgttccggcg ccgcggcgag gatcggcgct gcggccctga ccgccgcgac
  1221301 cacgcttgcg gccggaaacc agttcggccg acggctgatg aagccgagcg cggcaatgtc
  1221361 tgccttttcg cagaaacgct gcccccagaa gcggctgccg ttcgcctgca tttccatctc
  1221421 gttaaaggtg acgagaagat agggcgatcc tccgcgccga tggatgacct ccaggttttc
  1221481 gtcggcataa acaagcatgt gatttcccga gaagcagtga aattcgtttg aacggcagcg
  1221541 tctacggaac ggcctgtgcc aaggcgtcat attgttccgc acgcatcggg ccccgtttgt
  1221601 cgtccagcag gcggcggtag agatctgcat gcgcgcgggc cgactccatg tggctggtcg
  1221661 gctgccgcag cattgcgtgc agccgatccc acatgtccgg gtttccaagc acttcggcca
  1221721 accgatcggc gaggtcctga gcgcttccgg cccggaaatg cagcccatcc cttccgtccc
  1221781 ggactttctc ggccatgccg ccgatatcgg agcagatgac cggcctgcgg tggtgcaggg
  1221841 cttcctggat gacgacgggc gagttttccc accagatgga aggaagcacc acccagtcca
  1221901 ctgagcgcat gagcctcgcc atgtcgccat tctgataggc gccgtagaaa cgtacgcgcc
  1221961 gccctgcctc gtcgatgagc ttcttcaggc gctcctgaaa ttcgggcggc tgccgctcga
  1222021 ggttggcacc gaagatcatc agacaggaat cctcgcccca gattttttcc ggcacccgcg
  1222081 agaccgcgtc gaccagcacg tctatgccct tgaagggcgt gatctgcccg aaataggcga
  1222141 agcggttccg tcgggcggac ggaaccggca gatcgcgtat cggggcggct tcgcccaaga
  1222201 cgatgccgtt ttcgatcacg gagagctttt ccggatctat gccccattcg gcatagcgcg
  1222261 tggcgaggaa catgctgggt gagatgaagg catctgagag gccgagcatg ccgcggagga
  1222321 actcttcccg ccgtagaaaa cgcgagacgg gtatgtcggg aaagcaaccg tggcagctga
  1222381 tcggggacga actgttgcag agttgggcgg agggacgttt caccatttgc ccgtggttgt
  1222441 ggcaaagcga gagatattca tggaaggtga cgacgatcgc cgcctccggg agcgcttcgc
  1222501 gcagggcgta aagcgcctct atccccatgc cgatcaggtg atgaaagtga atgatgtgag
  1222561 gtgaaagatc cccgacgaag cgcagcaggt cgcgacggat cgcctccgtg tcgccgttgg
  1222621 acaggaagaa gtgatcgtag tcgtccgcat ggaaaagcac ctcgtccacg gcgagacgca
  1222681 ggctcatgag ggctgacgcg ccatgccgcg ggatcggatg gctgacgcgg gcgagataga
  1222741 tcgactcgac acccgccagc gtgttcaggc ccttgtgcag gctgtgggac gcaatttccg
  1222801 ccccgcccag cgacatcgcc ggatgtccat gtgagacgac gagaatgcga agtcgctcgc
  1222861 tcatgcggaa gcctctacca tgcgattgtc tctgctctct ggccccggcg cccaacgggc
  1222921 cgagaatagc ttttcgtcga tccgctcgat gaggggggct gcggaagcgc cgtcaggcgc
  1222981 ggatatctcg tcggagccca gcatctggac ggagggcagc caccaggatt caattccgat
  1223041 gcggctgagc ctgaggccga gatcctgccc cttctgctgg gatccgagat agctgccggc
  1223101 aaagcctcct gcggtgagga aaacctcgcg gggcaggatg cagcattcga acgacgccgc
  1223161 cgcgatccgg gtgagcttga gccccgtcac cgcgctcaat ggatacccgg cataccgacc
  1223221 cgaaagcgaa ccggattgcg ggtccgccca ggtgccggcc catcgaacgg aatggtcctc
  1223281 gtaagcgaga gtcggcgaaa tgacgccgcc cttctcctca tacgcggcaa gcaggttgcc
  1223341 gtaccagccg ctcctgcgag gcaataacga gccggcaagc agaacgaccg tctcgctcgg
  1223401 gagcgctcga atgcccgctt ccagcagatc gtaaacatcg tcggtttccg acgacatcag
  1223461 cctgagcgag agccgataga actgcgcgag ctgcctgata cgggcggcct ggcgccgaaa
  1223521 gcactcggag ttcagcacga gcgcgatggg ggcttgccgg gtttcggggt cgagagcgag
  1223581 aaggccaaga aacggcgcca gctctctttc ttcggtctgg ccgacagcaa cgatgatcgg
  1223641 cggacccggg gcatcgtcga acgcaccggc atccaggata ttcccggcgg tgggcgaggg
  1223701 gctttccgac gcgcacagga agggaacgat ctggcggtcg acaatctccg ccagccccca
  1223761 gttctcggga tcgatggact tgatctgccg gagcaccgcc cggcgcggcg gaagccgggc
  1223821 gggtgtcagc ggtaggaagg ctcggcggga atccttgagc gtcaactcca ggtgcaacgg
  1223881 ggccatgccg tcttccccca gcccgctggc aaacacgatg aagccatgag gatgtgtgtc
  1223941 ctggtcgagc atgcttttga acaggggctc gtcggaaaag gcgtcggtca catccgagcg
  1224001 ctcgagccgc gtccagcgat cgtcgagccg catgtccgtg ctcccgcggc gcaggcggac
  1224061 gctctgaaca tgtccgtccg gatcgagcag ccaaccggag atcagaaacg caccgctgtt
  1224121 cgcctgaaag atattgtcca ctcccaaccg caccggaacc gggagcgtgg agattgtctc
  1224181 gcgcccctcg aagctgtttg cagccgagcg cagtttgagc agaactgctg gcgagctgtg
  1224241 cgtctgtagc agcacggagc ggatttgcgc gggcgtttcg gcggggccgg cgatctgccg
  1224301 gctctgatga agcgctgcat agcgccagcc cccgccgccg cgatagacga gcccctcgac
  1224361 atcgcgcgcc cggaaaggct cgcttgccgc cagcaggcct atgaagccca cagctccttt
  1224421 cgggatgtcc tgccgggaaa aagtcgcgat agcacagtcg gcaaaaaccg gattctcgcc
  1224481 gcacacgatc acttgagtgt tgccggggtc ggccgcgcgg gcccagcctc tgaggaagat
  1224541 cgaaccctcg tgggtttctc cgacgaattc gaggaagccg tctccgccct ttcgcgattg
  1224601 tatgagggcg actatcaccg caagtctccg tcttccggcg gtgatctgta tcatcgcatc
  1224661 gacgagcgaa tccagtaccg cggtcaactg gccgccggaa agttccgcga ggatcgttac
  1224721 ggcctcgcga actgcaaggg tgcggggggc gaagatgtaa cgcctgccct cctggccgag
  1224781 ccgcaatgtg gtgagcgggc ggtcggcatc atcggtcggc agcagcgccg cgaaaccgtg
  1224841 cgtgaccgat ggggacggcg aggccaggcg ccaggcggtg acgtaggcgt tcgtcacggt
  1224901 agcggcatcg tcgttgattt ccgccggcag ttggccggcg gcaggcccgc tcgcgccgat
  1224961 cacgagcaac agcccgtcgt cgatcgggca ggcggcaacc ctcccgcccc gcattatcct
  1225021 cgttgcagta tgcgatgttg caggaagcgc ctgttctgca tcactcatga tcgtcctctc
  1225081 aagcgccggc aaaaagtgag agggcggctc ctgcggcaaa tcccgcgagt acgaaaagca
  1225141 ggagcagcaa cggttttaac tctccattcg accgcttctg caaggcaccg aggttcttct
  1225201 ccatcgctgc taccacgcca tcgagcctca tgagatggac atcgagatcg ttcaggcgct
  1225261 gcccgatctc ggcggcagcg ccgggtcgca aagtcccccc ttcgccgccc tcgtcattct
  1225321 gcgtgcgctg gaaagaccgc tgtgaaacct gcaattgccg ctgcgccgcc atgaggacgt
  1225381 ccagcttgtc cagaactttg gcaagcggcg cagcgataag ggcttccgcc gcctgctcgt
  1225441 ccgggcgcgg aacgcgcaac ttttgttccg tgccgcgcgc atccagggca gttaccgtga
  1225501 gatcggcagc gcgtgaggcc gccgcctcgg gaagcgcgat ttcgaatgca tggctgccgt
  1225561 ccccgattcc gttgcgcttg agatcggggc gattgcgatc ggcaaccgcc tcggcgatgg
  1225621 cgcttccgtc gacatatacc cggatggtga ggcgtttggt gggtgctgcc ggatcgaagg
  1225681 cccagccgaa gatgcgcccc tggtcgatcg cgtcgacccg gccgctcatc ggtttcgtgt
  1225741 tgtcctgctc cggagcggca tttgatttct cggaaacagc agccatcgat ttccccttta
  1225801 tgccgcttcg attcgtgacg gcgcaatcgt gtcgatcaat tcgagatagc gtcgggcggt
  1225861 cgtgtcgatg ttctcgggtt cgtgcgcgtt tgcggcaagc cggcgcgcca atccgccgtc
  1225921 ctgtgcaaga cggcgcatgg cagaggccag cgcccgcgga tcgttgggcg cgacggtgag
  1225981 cccgtttgac ccatcctcga tcaactcggc catgccgccg atgttgctgg ctatgaccgg
  1226041 ccgcccgaga gcctgcgcct cctggatgac caatggcgca ttctcccacc agatcgaggg
  1226101 cacgatcgtg caatccaccg aggcgacgag gtcgatcacg tcctcgcgcc gatagggccc
  1226161 ccgctgctgt acggttggtg ccgtctcctg gaacaggcgc gtgatctctt cgacgaagct
  1226221 ctcgctttgg aagggggcgc cgccatgaac gcgcagctcg aactccagcc cctctgcgat
  1226281 gagctgccgc gccgcttcga gcagtacagc gacgcccttc cacggattga gattgccgaa
  1226341 gtagccgaag atcggacgat ccgagccgat ccgacgaact gccgccggtt ccttgcgcgg
  1226401 cggcaatccg ttcggaatga cgctgattgc gtcttccgat aacccccatt cgacgaagcg
  1226461 cgttttaagg aaattgctcg gcgacacgaa ccggtcgacg tcgctcaaca gcgccttcag
  1226521 gtggcgttcg cgcagcgcga accggtcgag tgctatgtcc ttgaagcagg catggcatct
  1226581 gtcggggctc gctccgtggc aaagctcttt gccgctcgtc ctcaccatca agccgtcgtg
  1226641 atgacagatg ggataatagt catgcagcgt catgacgatc cggcactcag gcagcgtacg
  1226701 gcgcacgata tgtggaaact ccgcgccgag cagcagcagg tggtgaatgt ggacgacgtc
  1226761 cggccggaag tcgcgcagca gttccgccag gtcgggaacg acgccgtaga gatcgatctg
  1226821 gctcatgaaa aatcggtcga agtggccaga ccacagcagc agttcgtctc ctgccgggcc
  1226881 gatcccttga aagctggtgc ccgggcgtgc ctgtcggtgg atctggttgg tggcgcccag
  1226941 gaagagcgat tcgcagcccg cgcgcttata ggcgcggaac aggtcgtggg cgaaaatttc
  1227001 cgtgcctccc gggtgaaggg ccggatggtt gtgagccgcg acgaggacgc gcatgctcac
  1227061 gggccgctcc cccggcgttc ggcgacgaaa atgtcctgat agtgctccgc cgaaacccca
  1227121 cgccaggcac cgagcgactt caggttgatt ttgaggccgg cacgctcgag tgcgccgtca
  1227181 agaaagcctt cgtcgaaacc caccgcggca agacgcggca tctcgggaac gtaccagcat
  1227241 ggtccctcgc catcgcgtgc gaaggaaagg cgtgcatcgc gtcggccgct ttcgttcgca
  1227301 gccgcaacgt catcgaccac gaaggccgtc atgaagaggc ggccccccgg cttcagcagc
  1227361 cttccaactt cgcgcagata gacgagcact tcgtccggcg gcagatgggt cacgatggat
  1227421 gtcatgataa cgaagtcgaa gtgaccgtcg gcgtagggca gtttcagcgc attgccgctg
  1227481 atcttgccgc tcggattata aagctcatgg gcgatatcga ctcgctggaa cgcgaaattc
  1227541 tgataggccg gagtgatgaa gcgacggcac caggctatgc cgccttcaac cgggtctatt
  1227601 ccgctgtagc gtcccttttc gaaatccaga tactgggtga gcgggacggc cattcgaccg
  1227661 atgccgcaac cgatatcgag aacgcggctt tccggtcgta accctgccag acggatgaag
  1227721 tggccgagga attcgacgcc caccgccctg aaatccccgt cgcccacaaa gacgctgtcg
  1227781 gggttgggtt cgggcagaaa gcggtttcga agaatgcttc ccagcagggt ctccacgcgc
  1227841 tcgtcccgcg cgggcaggtc cgttgcatgc gtgttttcct ggcgtagtgc agtctcggtc
  1227901 atgcggcgct cctcgctgtg gcaccggcct cttggcggac gagcccttgg atgccgctgc
  1227961 cgagatatgc tgccatcagc gcctcgatat cgtcatccca ccgctccgtg tgcagccagg
  1228021 agttatactg gctggcgacg ccgcgcatgt agtcctcgct gcggcggatc gagcggcgtt
  1228081 cgaaatgata aagacacgca gacggctcgt agacgatgtc atagccgcac cggcggatct
  1228141 tcaggcacaa gtcgctatcc tcgtagtcgc cgattacgta atcctccgta tatccatcca
  1228201 cgcgctcgta ggtctcccga cgcgtgacga ggcacgcacc tgtgatcccc gggacgctcc
  1228261 tggaaaattg agcgggcgca tagtcgcctg gcatgccctt gtggaaatgg tggttgagcc
  1228321 atatgccgcg ctgatcgcga gcgaaataga gtcccgcgtg ctggagcgat ccgtcctcga
  1228381 agatcagctt cgggccgatg gcgccgaggc tcttctgttc catgagcggc cggatgagcc
  1228441 tctgcagcca gccggctgct gacggaacga cgtcggagtt cagcatgacg atgaccgcgc
  1228501 cgcgggcgaa gcgcgcgccg gcattgcagg cccgggcata gcccccgttg cggctcatca
  1228561 ccacgagctt catcggcagc ccgtggagga gatgcagccc gccaagaaga tgctccgtct
  1228621 cgtcctggat ctcgggtgaa tccagaacgt agatgatctc gacattcttt gcgagccagc
  1228681 ggtcggtcgc catgccggag agctggaacc gcagaaaatc gagaacacgg taaagcggca
  1228741 cgacgatcga aaccaggggc gccgtctgcg gcaggtcgta atccttggta tagtcgaccg
  1228801 tggcagttct gcccaatcga tgttctacgt cctgcagcgc gggggcaagg atcgtccgga
  1228861 aggccaggtc gactgcgtgc tggggcggca ccgcgcgcag gatgcggttg cgctgcgccg
  1228921 aagcttcgaa gggttgtggc ttcggcacga gcggttttac gacgccggaa gcgagccgca
  1228981 tctggaagcg cggctggagc aaggcgcccg gcgcctcgtt taacggcagc caggcgacga
  1229041 agccggttac gtcggcgcgc gtattgtcgt ccgttccgcg tgcccaggca ggaaactcgt
  1229101 accaattgcc gtcgaggggc accgccgtgc cgttctcatt caggtagtcg atgccggcga
  1229161 gcgtggctgt tggatcatgg gaccagcccc cggcgagcag accgcccgaa aggctcaatg
  1229221 cgagatccac ttctgcggaa ggatgcatcg atgatctgtc gatccgcctt gccggaagcg
  1229281 gtgtccgaag ctggaggtcg acggcggtcg aatgtccgcc ctccggtgtc gtcgaaagcc
  1229341 atcggacgac gaattcgcgc agctccggcg cgccaccccg ttcggcccac catgcctgga
  1229401 gactggtgta atgtggtttt ccggaggaga gttcgcgaac agccacgcct cgttttccga
  1229461 cgagaacata ggattgaggg tgtcgaggag actcgacaat gaagtggcag gggcgcaggt
  1229521 cgtgctcgcg atctgggccg gtcacagctt gcgactccag cggcaaaacg gcattggcac
  1229581 cgagcgaata gaccgcgctg atctcaccga agtcgggagt tatcgcggtc tcgatcagat
  1229641 accggcccgg catgatcggg caagcgatct ttgcaggccg cggcctcgat gtcagcgcat
  1229701 gaagggcgtc ctcgacgagg cctatgaaga atgcatcccg ggacaggcgg aaggcgctcc
  1229761 gccaaacagt aagcagagtg ttcacaaact tgacgcagcc ctccggtgtt agcgcggcaa
  1229821 acagggcttc cacgtcgagg ggcggaagtt cgccgacggg ctgcaggaca accgttcgga
  1229881 cgaagtcgct atcgacggaa atctgtccgc ggcgcggttc gccccctggg cgcatggccc
  1229941 aaaggacccg ctgaccgcct tccgccagag gaaggatggt gctgaccagc ggcacgggtt
  1230001 gctccggcat gacgagcctg tgttttgctg cggccggcag ttttttcttg aggtccgaga
  1230061 tcaatacggc cacttcggaa ccgagccgaa aaaccttcgc gtcctcgaaa atgccgctgg
  1230121 cggcccccat gcggtcgtcg aacgtcactc gccactcctc tgctgcaggg aagacgcgcc
  1230181 ccgcgggagg agggcagggc gcgccgttca aagtcaaagc gggataaaga aaaccgcctg
  1230241 cggttttcgg cctgcgtccc gcgtctcaaa ctatcagtgc acagtgaagt agttttccgg
  1230301 atgggcctga atgtcttcgg cgtcggcatt gaccagcgtc agcgtgtcgc catggccgag
  1230361 gtcgataacg acattgcctc cgacctgggt gatccgcgaa gcgagatcct ccggtgcggt
  1230421 gacgtcgagg ccgttgatgc ccttcgatat ctgcagaacg tcttcgccgg gggtaaagtc
  1230481 gaggatgacg tcgttgccgc cgccgccgtc gaaaacgaag atatcgcttc cctgaccgcc
  1230541 ggcaagaagg tctgaaccgg agccaccgtc gatcacgtcg ttgccggcac cgccgagcag
  1230601 aacgtcgtta cccctgcctc cgagaaggaa gtcgctgcca gcgcccccaa ggagaatgtc
  1230661 gtcgccgtta tcgccataga tgagatcgtc acccgatcca ccgaccaaaa cgtcgttgcc
  1230721 attttcgcca tggagaacgt cggtaccttc accgccgaac accgtgtcat ttccgttgcc
  1230781 gccgaacagc aagtcgtcac cttcatcgcc gaagatgatg tcgtccccgt tacccccgtt
  1230841 gacgaaatca tcaccgccat gggcgcggat gaaatcgtca aagcgagagc cgaacagggc
  1230901 gtcgtcgtat gcgccgcctt ccaaagtggc catctgcttc tcctcttcgt ggtttgatgc
  1230961 atgcgtcatc ggcacggagc cgaggattgc gtgccggagt gtgcaccgca ataatttcga
  1231021 acgcaacaca gatgtaccaa taaaaccggg aagaaattgc tataaattca tcgcagtaaa
  1231081 cataacctgt ccctgtgcta atattggcac aatataattt taggagttat tcttgcgaaa
  1231141 atgcaggcaa accggttcaa aatttaaagt aaattgccga ttgatgcgtt ggatgagaga
  1231201 acgacttcaa tcctcccgga aggcgcggtt gaaactgtcc gagacgggag agacgaggta
  1231261 atcgattgcc gagcgggctt tgtgcacgat cagcacttcc gcgggcatgc ccggataaag
  1231321 ccgaatgtca ggatttgcgg caagcgattc cggcgcgatt tccgcccgtg cgacgaaata
  1231381 ggcgacattg gacttttcat ccatggattg gtccgcggcg atataggtga ccttgccgtc
  1231441 catgggcagg tgcgaacgct ggttataggc ggtgaggcgg atttgcgtgc tcgagccgat
  1231501 cgttatgctg tcgatgtccc gcgtgctgac atgcatctcg acgagcagcg gctcgtcctc
  1231561 gggcacgatg tcgagaagcg gctggccggg cgtgacggca ctgccgggcg tgcgcagctg
  1231621 aatgttggcg acgatgcccg cctggggcgc acggatttcg aggcggcgca gcacgtcctt
  1231681 ggcggagatg atgcgctcct cgacttccgc aagctcgagg cgcgccgttg taatctctcc
  1231741 ggcaatctcc gactggaaat ccgattcgat tccggtgagc gtgagctccg cgcctgccat
  1231801 cgccttttcc gcctgcgccc tgtcgcccgc aatttcgccc cgcgtcgcgg cgagttcgct
  1231861 gagccgcgcg tcgatctcga tgagtttcga tcgctgggcg aacgcctttt cgaccagggt
  1231921 cgcgatcgcc gttcgctgct cgttcatcag ttcaatctgc cggtctgtcg cctgcaactg
  1231981 agctgtgaga gacttcgctt tctccgaata ttcctcgatc gtcttccgct ggatcgctat
  1232041 ccggccctcc ttggcctcgt tgcgcttctc gaagaacgcg gtttccgccg tgactgcatc
  1232101 cgcggcggct tcccccgcag cgacgaggtc gtccgggaag tcgaccgcct gcaagcccga
  1232161 ccgctcggac cgaagccgcg caagctttgc gatcagaccg acacggcggc tctccagcgc
  1232221 ctgcaggtcg gagcgcgcac gcgtatcctc cagttgcatc agcggttggc cgggagccac
  1232281 atgatctccc tcttgcacga ggatacggct gagcacgcct ccctcgaaat gactaaccgt
  1232341 cttgcgtttc gaatcgacga tgatagtgcc actcgtgacc gaggcactgc tgagctccgt
  1232401 tgaaaatgcc cagccgaaga agccaccgaa ggcaacgagg atcgtcgtca gcccggcgat
  1232461 gacgaggcgc cggatgggcg accgcgtttc gttctccagg aggtccggct ccggcattgt
  1232521 cattggcagc cgcccctgcg cggctaccgg caggcgacgt tccgtgcttt ccgtctccgc
  1232581 gggcggctgc agatcgaggc gagccggcag gatcgtttcc gtcttcatgt agcagtacct
  1232641 tcgcgtctcg tttcgcccgg gatcatcgag gccaccacat ccgttcgtgg gccgaactgg
  1232701 ctgatgcggc cgccttccag cacgagcagc ttgtcggcca cctgcatgat agccggccgg
  1232761 tgggcgatga ggatgacgat ggcgccgtct ctgcgcgcct cctcgatcgc gcggataaga
  1232821 gcgcgctcgc cgatggcgtc gagattggcg ttgggctcgt ccaggacgag caggcggggc
  1232881 cggccgtaga ggcagcgggc cagagcgatg cgctgccttt gccctccgga aagggtgagg
  1232941 tggccatcgc cgaccggcgt atcatagccg agcggtagcc tgccgatcat gtcgtgcaca
  1233001 tcggcaagcc gcgccgcctc gagcaccttg taagggtcgc tctccgccat gcgtgcgatg
  1233061 ttttcacgta tcgtcccttc gagcagggac accgactgcg gcaggtagcc cgccacctga
  1233121 ccgaacgagc tgcgctccca gaggtagacg ttgttgccgt ccagaaaaac accgccggca
  1233181 gtcggcttca gaatgccggt gaggagccgc gccagcgtgg atttacccgc ggcggatggg
  1233241 ccgacgatac ccagcacctc accgggcgag agcgagaagt tgatgccctt gatgatcggg
  1233301 acatcaaggc cgggtgccgc atagaccagt ttgtcgacga caagctcgcc ttccgagcgc
  1233361 ggcgtcggca tcgtctgacg aacggcgagg tcctccttca gtgccgcttc gacgcggcgc
  1233421 cagcttgcga tcgccaatac ccattgccgc cagttttcaa tgacggagtc gaacggcagc
  1233481 agaaggcgcc ccacgagaat ggtcgtcgcc atcatcgctc cgggagaaat ctcctgccgc
  1233541 atgacgagca gcgcgccggt gccgagcgcc gccacctgaa tggcaaagcg cagcgatcgg
  1233601 gtgatcgagg ccatcgccct gcttctgatt ccgctggctt ccagcacgct cagggcgtgc
  1233661 agctgagcgg cgcgccactt ttgggagagc gccgggagca ttcccatcgc ttcgatggct
  1233721 tcggcgtgac gtaatgtcgc acctattttc gagactgcct caatattagc ctggcttgcc
  1233781 tctttcatga gctgacgcgt caagaggtcg ttgaggaggc cgcagcagac gagcacgacg
  1233841 acggagatcg caccgatcaa tccgaagagg ggatgcagca gaaaaaggac gcccagaaag
  1233901 atgggcgacc aggccgcgtc gagcggagcg ctcaccgcag aagaagtgag gaagctgcgc
  1233961 agctccgtga ggtcgcgcag agactgcgtc gcccgtgcaa gcccctgatc ggccgacgcc
  1234021 tgcacggcgg cggtcagaac cggcaggttc aaccagcgga ccacggcgct acccatggcc
  1234081 tgaaaggtga gagcgcgaat gaaatcgagc acgccgagca cgatcagcgc gccgacagca
  1234141 agaatcgtca gcatgacgag cgtatccatg ctctggctgt tcaacaccct gtcatgcacc
  1234201 tgcatcatat aaagcggcat ggtgagttgc aggaggttga tgcaggcgct gagcagggct
  1234261 gcataaagaa gcgtcacgac gaatacgcgc cgggcccgca gaacgagcag ctttggagcc
  1234321 attgttccat tttgtggcgc catcgatcgg ctatggccct tgccaatcaa aggatttcga
  1234381 acagtatcac gcatgtggcg atcttctgaa taacgctttc gcgggtttca tggggcgatc
  1234441 tggttcagat tcactcaaat cacagtattg ttgcgatgag tgtgacacaa taaacatcgc
  1234501 tcgctcaagg gcgttgaatt tcggggcagg ggtgtcatga atttgcttca aatattgaag
  1234561 taaatttccg aaatatgaag tacgttctct atggagagag ggatgaacca caggatgctc
  1234621 tatccgttcg cagacttcgg agacactgtt tcagtccttc ccgcgaatga aacaatgcgg
  1234681 aaaggcctcg agaccctagc agccgaccag gacggggata attcgctcgt tacctatttt
  1234741 gagcttgcca gggtgatgga gcgcgcaagc cgcaggtttt ccggcctctt gcgggcggag
  1234801 ttgacaaagc tcggggtcga cgacatcggc ccggcgcagg cgatggttct tcttgccatc
  1234861 ggcgacgcgg agctttcggt gggagagctt ttggaccgag gccactatgt gggttcgaac
  1234921 atttcctatt acctgaaaca gcttgccgat ggcgactaca tcgatcgaat cgcatcgcag
  1234981 cgtgacaagc ggtcggcccg catacggctg tcggtgaaag gcaggcaggt ctgcgctggc
  1235041 ctgcgggagg cagcgaaggg ctacgaacgc gccctcagcc acggagagca ggaccggcgg
  1235101 aatctcgaga ccgccttcca gaccctgcac cgcctcgaac tggtctgggg caatgccgcg
  1235161 cgttacggga tctgaggctc ctccatcgca ttcgtccttt gatcatagcg gaccaaggga
  1235221 cagagacatg caaaatgctg ctcagatctc agcgcgtccg atcggacgcg cgtgcactgt
  1235281 agcggcgatc tctcaccaat agctggttta agaacatgca tgtagcattc gtacaccgcc
  1235341 gtggtttcgg ccagttcgcc gccttggcgc ggcaccttgc cgaggcgggg aacgaggtca
  1235401 ccctcgtgac ggagaccgtg gatcagcgga taccatccgt tcgggtcgtc cggcatcggg
  1235461 cggagccagg tccgcagccg aacccgcata ttgcccgtca cttcggggtt cccgatcatc
  1235521 atgtgcgcat cgggcacagg gttgcggaga cattcgacgc catgcgccgc ctcgggcagg
  1235581 ctcccgacgt cattctcggc catataggtt ggggcagcat gatgttcgtg aaggatgtcc
  1235641 tgccgcgggt gccggcactg ggctattgcg agtttttcta tcgggctgaa ggagcggatg
  1235701 tcggctttgc gcccgacgac cgtcccgatt ccgagacgcg gaaacgcttg cgccttcgca
  1235761 atgtggcgca gctcctttct ctcgaagcga tggatggcgg catcagcccc acgaactggc
  1235821 agagaagcct ctatccaggt gacgcgcagc aaagaattgc cgtttgccac gaaggcatag
  1235881 acacgcgccg ttttcgctcc gatcctgcag cttcgctgaa gcttccggac gggcgtgtcc
  1235941 tgaaggctgg agatccggtc gtcactttcg tcgcgcggga ccttgaacct tatcgcgggt
  1236001 tcccgcaagc actggaggcg gcggcgaagg tcgtccgacg gcatccggac gcgctgttcg
  1236061 ttttcgtcgg cggcgacggg gtcagctacg gcgcgccgcc ccccggcggg ggatcgtgga
  1236121 aggatcatct gcttgcgtcg ctggacgttc cgcgtgagag acttattttc ccgggcgtcg
  1236181 tgccgcattc ggtgttgcga caactctttc agatctccgc ggcgcatctc tacctcacct
  1236241 atcccttcgt gctttcctgg tcggtgcttg aggcaatggc ctgcggcgcg cttgttatcg
  1236301 gatcggatac ggcgccggtt caggaagtca tccgctcggg ccgcaacggg cttctcgtcc
  1236361 cgttctttga ccccgacacg ctggccggaa cgattctgga cgtgttgaag ggtgcagagg
  1236421 gggtcagtgc aatgcgccgc gcggcgcgca gaacggtgga gcagaggttt cggttggacg
  1236481 attgcctcgc gcgccagttg aagctggtag acaatctcgc ccggcggaat gctgcactag
  1236541 cgaaggaaac gcagattacg tagacattac ttcaattgtt gaactataaa taccgataaa
  1236601 aaccccaaga atctattgtt gtgcagtgcg gaatccgagg atatgttttc cgcaaatgaa
  1236661 gttccgatcc gtgagtattt acggttctaa atttcatctg tcatttaatc gaaatattct
  1236721 ggggtcgctg cgtgcaagag ttgatgtctt ctagcgtgag gcaatcgccg acgaagcgaa
  1236781 ggctggttgt ggcatccggt cttgaccgag agaacgtcga ggggagcgac atcgagcatc
  1236841 tggtccattt tctcgatccg gatgcttcac gctttccctt gcagaacgcc tttcccctga
  1236901 ttgcgctggc cttctccgat gagggcgaga ccgatctgcg cgaagggctt gcatctgtcc
  1236961 acgcgcttgg caccataccc gagataccgc ttcgacggat cgacgtgccc gtcaaggcgg
  1237021 agagtctttc gctgatacgg acgttggtcg agggtggagt agggcggctc tcccgcttca
  1237081 cctcggccgt aaccgccgaa ctggctattc tccgtcgcga gcgggaaacg ctgctcgaga
  1237141 attaccgcgc actcgaggac gcctttcaag ctcacaattg ggagccggtc gcggagattt
  1237201 tcgcccatga tccctatgcc gatccgaagg acgagggcat cgggcaactc ctgtccaccg
  1237261 gctgtgtcga gcagttgctg cctgtctcca gccatggcgt ggcgggattc gcgctgcatc
  1237321 tccattccgt gccgagggac gggggcgaac tggttgtcat gctgggctat gtcgagaacg
  1237381 gcgagggcgt agccgagtgg accgtcccct atgcgcagct cacggcaaac tggaatttct
  1237441 ttgcgctccc acgcgcttgc ggcggcgcgg cgagaacgct gcgcctgagg atttccacga
  1237501 ccgggacgga gactgtcgag ctgtcgctcg gctatccgat tgcgagcgag cgctacacgg
  1237561 cccgatcgga aacaccgcat cctgatctcg atcttcggcc gctggcattc cgggtgttta
  1237621 cggggctgcc cggcgtgaag ccggcacgaa tgcccaacat gatcgctccg acggcgttgc
  1237681 tggagggtca cttcatcgag gactatcgtc tggcggtcga cctgctaagt cagatcgtcg
  1237741 atgtttctgt gaccccggtc gtcccggagt ttcagaccgt tcgcttcctc gagcacgaga
  1237801 acgccgtcgt ttgtcatccg ttaccgagcg ggatatccgc cggcacaatt ggccgggccg
  1237861 tggaacccgg caccatctcc ttctccgcga gcgcgataat cgatcacccg aagggcgcgc
  1237921 ccgcggccgt gagcttcctg ctcgctccgg caaactccaa cgcgcgctcg gaagtggcgg
  1237981 aacttgcacg taagggcgcc gcgaagccct cggccttctt cagcggctgg cgcgaggtta
  1238041 cggccgcgca ggcgatcaac atcaacttcc agctggacaa gcccgtgcgt gagccgatgg
  1238101 acctcatgat cctgagccgt gccgtgacgg atacggtcga tttctcctgg ctcaaagtct
  1238161 ccggcttccg gttggtgaag cagtccgcag gggcgtccaa tgtccggcaa tagggaagat
  1238221 accgacctca tagtggtggc gatgccgctc tacggccatg cagccctcgt tctggaggcg
  1238281 atcgaatccg ttctcgcctc gaagctctcc ggatgcagtg tagcggtcgt cgtatcggtc
  1238341 gatggggatc cgcgacagga gaccttcgat cagctgcttc tctacgcggc ggcccatccg
  1238401 gcggtccatg ttctcttcgg cgccaatgcc gggccgggcg gggcgcgcaa ccgtgcgatc
  1238461 gaatacgttc tcgcgaacct gccggaagcc gaagcagtct atttcctcga tgccgacaat
  1238521 cgcgtgctgc ccgggaccat cgagacccta tacaggcaac tgcgcacaag cggttgcggg
  1238581 tggatttaca ccaatatcga cactttctcg gtgagctggc gcgcccatta cggcaatcgc
  1238641 tactcgcggc tcctgcactg cataacggac aatatctgcg acaccggctc catgatctcg
  1238701 ctcgatgtgt ttcgggcggg ggttcgtttc gacgccgaca ggcagaacgg tttcgaggac
  1238761 tgggaattct ggctgtcctg catcgagcac ggcttcgtcg gagaaccatg ccacgacacg
  1238821 accttcgaat accggctaag ggcggagagc cggttcaagg aggcgaaccg cgatcgcgct
  1238881 gcctccgtga gcttcctccg aaagcgccac agggcgctgt tccagcgccc catgctcgtc
  1238941 gatttcgagc atgaggaatg cccgcgttat ctctttgcgc ggacggaaga cgccgccatt
  1239001 tcttacttta ccgacccgac aaaggcacct aagcggcttc gcctcgacga tatcattccg
  1239061 gcgttctggg cgagcgtcgg tgagccggac aacgtgcatt tcccgccctt cctgatcgcc
  1239121 ggaagcggcg ccacgctcga cctgctgctg cgctcccgga tgctgccaaa cgtgctctcc
  1239181 cacctggagc gcctgagcga gaaggccaat gtggtattcg tccagctcgg caacgatgcg
  1239241 gctcagcgca agatcgaacc ggtcttcctt gaggccggcg cccagcataa cgcttcgccg
  1239301 gacctcattt ttctgtccac atcgctcgtg cgcgacgtca tccagaacaa ggcgctggac
  1239361 tggttcgcgt ccatcggcaa tcagcaggtc tggccgacat cggctatctt gaaagtgcgt
  1239421 tttcccttcc cgagaagcct gccgcgccgt ttgctcatca caccccagca ggtgatgatc
  1239481 aactgcgtca acgccatcgc gaccagcccg ctgcggcgaa cggccggcaa acgctggacc
  1239541 tggcgcccgg cacggctcgt tccctattcc gatcttcaca aagcccttcg ccaggaggtc
  1239601 ggaggctcgc ccatattgcc gctcggccat agcgaggggg gcagaaaaac ggcggccctg
  1239661 ctcgtgccca atgcatcctt cggtggcgcc gagaaggtcg tatacgctgc ttcgcgcgag
  1239721 ctgaaggctg cgggctacga gacacatctt ttcgtgctcg gcacatccag aatggatgtg
  1239781 atcgacgagt tcgaccagag cttcgattat attcacttct gggaccaggg tatccccgcc
  1239841 tggggcggct ccggctcgtt cctggggcac gatttcattg ccgaaggcca tgacgtcgat
  1239901 tgggccgcgc tcaagggtca gctttcaggc ttcgacctcg tgatcaacaa tcacgtcatg
  1239961 gcggtgcatc cgcttatcgc gcgcctgcgc tcggaaggaa cccgaacagc ctgctacctt
  1240021 catgtggtcg acaataccgc cttcaaaaga cccgccggcc agccttttgc ggcgatcgcc
  1240081 cacgagcatt gctatgatgc gttcctgacc tgctcggaac agctcaagct ttatcttcac
  1240141 agtttcggcg tgccgcatga aaagatcttt gccgtaccca acggcgcgag cttctccgtg
  1240201 ccgcccaagg tcctgtctga agtgctttcg gtcagacgga tcgaacggaa ggacgatcgg
  1240261 cttcgggtgc tctatatggg tcgcctcgac cagcaaaagg ggatcgatcg tctggctgcg
  1240321 gccatcgccg agctgcgcgc gtcgcgcgtg cctttcgatg cccgggcggt tggcggtgag
  1240381 attcttgcgg atgccacgat atcctggacg gatcgcctga gggacttggg cgtcgaagtg
  1240441 cgctcaccgg tcttcgccag caaggatctg atcaaggcgc tcggttgggc ggatgtcctt
  1240501 ctgatgccgt cccgctggga gggggctccc ttgatgattg ccgaggcaca gcagctcggc
  1240561 tgcgtaccga tcgcgacggc ggttggtgcc gtcgacgagc tcatcaccga cggcgaggac
  1240621 ggcattctga tcgaggccgc ggccgatccg caggtggtgc gggatatggc aaaggccatc
  1240681 gaggaagtgg ccctcaatcg taagcagctg gcgcccctca tggaaggctg cctcagaaca
  1240741 gcggcacgcc gttcatgggg atcgtccttc tccgagttcc tcggctggtg cgatcgctct
  1240801 gtgcataatt catcgctttc gcgcgcaacg gtcatacgtg gccgcgaggc atccaatccc
  1240861 ggagtagcgg ctgtgggctg aggccccgcc gatttaagaa aagaagggtc gattgcatgc
  1240921 gtccacggat cctcgtgacg ggaattcctg gtcactacac gcgcctcgcc aacggcgcgc
  1240981 agggattatc cgtctcctat tcggagcggc agaaacagcc cgaaacgaag gaggagttcc
  1241041 tgcaggagct tcgcaatatc agcaataccg gcaattatct gatcggcgag ggggcactgc
  1241101 gggcgattgc cccgcatgcg aagcaggtgc cgttttggca cctttacaat tgcagccaga
  1241161 acggcgtcgg cctcgaggag ttcaatgcca atttcgacat ctgcgtgttc acctgcgcga
  1241221 accttttgcg aaagggcctg tcagcggatg ccgaggcgga agtgctgggc aagctcaaaa
  1241281 tgccgatcgt catgctcggc atcgggctgc agaaccggcg ggacctggaa aacagccttc
  1241341 cggaaggcac gaagcggctt ctcgacgttc ttaaggagcg cgagcactat ttcctgacgc
  1241401 gtggcttcga gacggcaggc ttcctcaagg atcagggttt ctcctacgtc cagccgaccg
  1241461 gatgcccttc catctatctg atgccgcaca atatgcgcgc ctccctgaag aagctgccaa
  1241521 aggtaccggt gggcaaggcg cggacgatct tttccggtta tctaggtgcc aatcacgact
  1241581 gcatcgtcga tgccgcggca ctggcgccgg agggttcgcg tccccaatac gttattcagg
  1241641 acgaattcct tcacttcgac atgaacgtgg aagcgaacgg cgatggacgg gtgtacgatt
  1241701 ccgcctcggg agtgatgctc ggtgagctga gttatccggg cacggaacgg ctgaagacgc
  1241761 ccttcgacgt ccgtaccttc ttcgacacga accagtggcg cgcctgggct tcttccatgg
  1241821 atttcaattt cggccgacgc ttccacggct cgattatcgc catgcaggca gccgtgccta
  1241881 gcctgatggt ggcagtagat gaccggatgc gcgagatgct cggctatacc gggctgccgg
  1241941 cgatcgacgc cgtcgaggtc gacaaggcgg ataaccgggc tgaattcgtc gccgaccacc
  1242001 tggccggact gaacgcatcc gaactggtcg acagatattc cgatcgcgag cgcacgttcc
  1242061 gctcggcgct cagagagatc ggaataggtc aatagttttc atgagcgtgt gctggctcca
  1242121 atctcaggtg tatcgatgcg tatcttgctt acgggtatcc cgtcctatct gcagcgaacc
  1242181 gtctcgggcg taaacggcgc cgaggtccgc cacaggccct atttcgatga ggtcagaacc
  1242241 aagaaggaac tgatcgatca ggtcaagaag atcgccaata ccggcaacta cctgatcggc
  1242301 gagggcgcgg cccatgccct gcgcgggcac gacgtcacct atttgccttt ctggcacctc
  1242361 gtcaatagcc ggaactccga tgaggtttat gagcgcctta atgaggaatt cgacatctgc
  1242421 gtgttcgctt cggccaacct tctgcgtccc ggctattcgg ccgatctgga agcagaggta
  1242481 tttcagaagc tgaacatgcc ggtggtgatc atggggatcg gcattcagcg gagggaaggg
  1242541 ctcaaggaaa acctgcctcc cggcacgctc aagttccttg aggttctgaa gaaaaaggag
  1242601 agcttcttcc tcacgcgcgg ctacttcacc gccgagttcc tgcgggagca gggtatgaag
  1242661 ttcgtcaagc cgacgggctg cccttcgctc ttctttgcgc cggtcgagat gaagcgttcg
  1242721 ctcaccgcgc tggccaatcc ggagctcgcc tcgtcgcaga agatcgcctt cggaggctat
  1242781 ctcggaagcg ttgccgacac gatcgtcgac gcccacgcac tactgaagcc ggaaagcgtt
  1242841 gcgagctatg tcatccagga cgaggtggtc gcctacaatc tttcccttcc cgtggacgac
  1242901 gacctgcctg tttacgaccg cgcgagcggg cgcattactg gcgataccgc ttacaagcat
  1242961 tcggaaaagt ggcagcgtaa gcacgagctg ttggtgttct tcgataccaa tcagtggcga
  1243021 agctgggtct ccacgcggga tctctgcttc ggccgccgct ttcacggctg catcatcggc
  1243081 atgcaggcgg gcgttccttc gctcatgatc gcggtcgacg accgcatgcg ggaaatgctg
  1243141 gagtttatcg gattccccta catggaagcg gcgatctgga accgggaggc ggacaggaag
  1243201 gcctatcttt cgagctttct gtccaaaatc gactcgcagg cggtcatcga ccggtattcg
  1243261 gcgtgcgaga ccaacttccg aaatgctctg gctcatgtcg ggctctagag caattccagg
  1243321 aaaagtgcgc agcggttttc cgtccggaat tgcgcagaaa catagggctg gagcacttct
  1243381 ccttaccgcg ttgctggcgc tcacggcacc ggcgcatgcc ggcgaagtgc cggcggttcg
  1243441 tatcggaatc aaccggatga atctcgcctg gctgccccgc agcgaacagg agaaggtttt
  1243501 gaaggacatc gccatgagcg gcgccactga tatccgcctt tcgctttcgc gtccgatcga
  1243561 cgagagcatt gaggcgctgg cgatcgctca ccggctgggc ctgcgtatcc ttctggaaat
  1243621 ccagctgggc aacaaaagct actatccgca gagcgcaggt ccgagaacgg gccatggccg
  1243681 catctgggat gtctatcgat tatcggatct tgatctcgcg cgataccgca gggaactgca
  1243741 tgatgcgctt cggcgtatcg acgccctggg aattcgtctc gaagcgatcg agcccgggaa
  1243801 cgagatcaac tacgccggat ataacggcga ccttgccgtt tttcgcaaac cgggcacccg
  1243861 gaccccgcgc agcctcggcg aacttcagga ccgggctggc ttcgagcgcg gcctcgacaa
  1243921 ttacgtgcag gcggtcgcga tcacccgatc ggaggtgcgc cggaccacgc atagccgcga
  1243981 tgcagccgtc atttccgctg gcctctcgga tatgagtgcc gctgaggccg acaggcgcgg
  1244041 gatggaaagg ctcgatcccc accaactcgt cgcgcttctt caagagcgtg gcatcgatag
  1244101 cctggtggat gcctatggca tccacatcta ccccggcagg aaagcggcgc ctgccatcgc
  1244161 cgcgcgcgtc agaagcctcc ttgagttctg ccaaccggcg gccacgggca ggtcctgctg
  1244221 ggtcaccgaa tgggggatcg caaatacggc gcgctcgtgc cccgtggatg atcgatcgcg
  1244281 aggaaaggcg atcggcgcca cgcgcgctgc tttcggcgaa tttatcgagg caggccggct
  1244341 gacggctgcc tactattacg actgggacag cgagccttcc tatagtctct ggcgctgcgg
  1244401 caagctcagc ccggacgcgg ccaccgcact cagcccgctc gagtctgccg gagcgcgagc
  1244461 acgatgatgt cggcgagcga aggcaatccc atgagaggca tcatccttgc aggcggccgg
  1244521 ggaacccggc tttaccccgt gacgatttcg gtctcgaagc aattgctccc cgtacacgac
  1244581 aagccgatga tctactaccc gctcggtacg ctgatgctgg cgggcatacg cgagatcctg
  1244641 gtgatcacca tgcccaggga ccggccgctg tttgaagaac tccttggcga cgggagccag
  1244701 ttcggcctcg cgatctccta tgcggagcag ccggagccga atggacttgc cgaggccttc
  1244761 gtgatcggcc gggactttat cggcgatagc gctgtcgccc ttatcctcgg cgataatatt
  1244821 ttctacggcg cgggcctgcc cgagctgtgc agcgcggcca cggcccgggc gagcggtgca
  1244881 acgatcttcg cctaccgcgt cgatgacccc gagcgctacg gcgtcgtaag cttcgatggc
  1244941 aatacggggc gggcggagac gatcgaggaa aagcccgcgc gggcacgatc gagctgggcc
  1245001 gtgacaggcc tttatttcta tgaaaacagc gtggttgaga tagcttcttc aatcaaacct
  1245061 tcagcgcgcg gcgagttgga aatcactgac gtaaaccgcg cctatctgga gcgcggtgac
  1245121 ctgcacgtat gccgccttgg gcggggtttt gcatggctcg acacgggcac gcaccaaagc
  1245181 ctgcacgatg ccgcttcctt cgtgcgcgcg atcgagcatc ggcagggggt caagatcatg
  1245241 tgccccgagg agatcgcctt cgagctcggt tacgtctcgg ccgatcaggt gctcgagcgt
  1245301 gccgacctgc tcggcaagaa tgattatgcg ttctatctcc agaggcggat tagggaactg
  1245361 gcggatgctt gaagtgaggc cgttgtccct tggtggcgtg ctggagatcg tgccgcggaa
  1245421 attcggtgac gaacggggct tcttttcgga aaccttcaat gcggagaccc tggccgccca
  1245481 aggagtcgag ctcagcttcg tgcaggacaa tcattcctac tcggcattgg caggtaccct
  1245541 tcgggggctg cattatcaac ttccgcccaa ggcgcaggcg aagctcgttc gcgtcgtgcg
  1245601 gggccgggta ttcgacgtcg ttgtcgacat ccgcaagggt tcgccgagct tcgcaaagtg
  1245661 gctcggtctc gaactctcgg ccgagagatg gaaccagatc ctggtgcccg ccggcttcgc
  1245721 acacgggttc gtcacgctcg agccggagac ggaagttctc tacaaggtca ccgagcatta
  1245781 cagcgcggaa cacgagcggt cgatccgctt cgatgaccct gcgataggaa taggctggcc
  1245841 agtggctgcc gatcgcctgc aactgtccgc gaaagacagg aacgcagcat tactcaacga
  1245901 atccaattta ttcgagttca ccgcatgagg ggagaagcca tgcgagtctt ggtaacgggt
  1245961 ggcgcgggtt tcattggttc ggcggtctgc cggcatctga tccgatgcgg ggcggagcgc
  1246021 gtggtcaatg ttgacaaact gacctatgcc ggcagccttg cgtcattgcg agcggtggaa
  1246081 ggcgacccgc gctatgcctt ctaccgtgcc gacattctcg acgaaaaggt cctgctgcag
  1246141 atcatgcgcc gggagcgcgt ggacgcgatc atgcatcttg ctgccgagag ccatgtcgac
  1246201 cgttctatcg aaggccccga ccttttcatg gagacgaacg tcctcggcac ggtacggctg
  1246261 cttaacgcgg cactcgccta ttggtccggg ctaggcctcg aagggcagga gcgtttccgc
  1246321 ttccatcatg tctcgaccga cgaggtcttc ggcgacctcc cgttcaaccg gggcatcttc
  1246381 tccgaggaga gccgttacgc gccctcgtcg ccttacgcgg cttcaaaggc ggcggcggat
  1246441 cattttgcgc gcgcctggca tcgcacctac ggcttgccgg tggtcgtctc gaattgctcc
  1246501 aacaattacg gcccattcca tttcccggaa aagctgatcc cgctgacgat catcaatgcc
  1246561 atagaggaag agcctttgcc gctctatggc tccggagcga atgtccgcga ttggctccat
  1246621 gtggacgatc acgcagctgc cctggacctg gtcataagcc agggcagacc aggggaaagc
  1246681 tataatatcg gcgcccgtgc cgagcgcaat aatctctcgg tcatggagag catctgcgat
  1246741 ctcatagaca tgaaattgcc gcgcaagggc ggcggcagct acagggacct catcaccctt
  1246801 gtccccgacc gtcccggtca cgaccggcgc tatgcgatcg atccttcgaa ggtcgagcgt
  1246861 gagctcggct ggagaccgaa gcggagcttc gaggcgggat tgagcgagac ggtcgactgg
  1246921 ttcctcgcaa accgctggtg gtgggagccg atccgacgtg aacgccattc gggatcccgc
  1246981 atcggcgggc tgcatcggag cgtggcgtga gaattgtcgt gacaggttgc aaaggtcagt
  1247041 tggcccgcag cctgctcgaa caggcacgcg gactgcctgg aactgaagtc atcctgatcg
  1247101 ggcggccgca gctggacctg acggaccctc caacgatcct ggcggcgatc gaaccgcacc
  1247161 ggccggatct cgtcgtgtcc gccgcggcct ttacggctgt cgatcaggcc gaaggcgagc
  1247221 cggagacggc ctttgcagtc aatgcgttcg gggccgaggc ggtcgccgga gcggctgcct
  1247281 ccctcggggc gccggttctc catgtctcga ccgattatgt cttcgacggg agcaaacacg
  1247341 gaagctacgc ggaggacgat atgccggctc cggtcagtgt ctatggcgcc tccaagcttg
  1247401 ccggcgaact ggccgttgcc gaggcgaatc cccgccatgt cattctgcgc acgggctggg
  1247461 tctatagtcc tttcgggaag aatttcatca agaccatact gcggctcgcc ggggagcgcg
  1247521 aggagatcgc ggtcgtcgcg gaccagtggg ggaatccgac atcggcgctc gatcttgcgg
  1247581 atgcgatcct gggcatttcc gcacagctga cacggtgcgg ccgggatttc gttttcggtc
  1247641 tctatcatct tgccggcgcg ggcaccacca gcagagcgga tctggcgcgg catgctcttt
  1247701 cggcaagccg cgctgaaggc ggtccatggg cgcatgttcg agatgtcgcg accagcgcct
  1247761 ttcccacgcc cgcaagacgc ccaaccaatt cctcgctgtc gagcgccaaa ttcaccgcgg
  1247821 ctttccgctg gtcgatgccc ccctggcaat attcggttga gtgcaccgta aggcggctcg
  1247881 ttcaaagcac ttccagtgaa acgatctaac caccgagttc agtgcggagg cttcgggtga
  1247941 aggccagaag cgattgctgc ggatcgtcgc cttcgccggc gagaacggtt acgccccatt
  1248001 tgccgagaac cgctttctgg accggattgg gccgatacat gaagacatag gaggccggcc
  1248061 gatccttttc gtgacctgat ctctgccagg tgctccagat gcggtggaga agcaggcgga
  1248121 tgttcaggtc agacatgctg tagccgacga acagcacagt tgcttccaga gcgtcgctgc
  1248181 gaaagcggac gtcgagcggg gattcgaagg acagccggtt gaaatagtcc gtttcggtca
  1248241 ggatgagcgt gtcgtcatcg tcgaagtcgc catgatactt gatgatccgc gtgacgccgg
  1248301 ccggcgcgga ggcgatgtca cgcacatggc tgatctttgc gtagcgcttg ccgtaaacgt
  1248361 cgtaggcgct ttccaaattg ctgtcgtagt tggtcgtgta aatcaccggg aagtcgagct
  1248421 cgacgatcaa ccgatgtaac tccgatcgtt tgatgcgctc cggggagatg cgccagttgt
  1248481 gccgcatcca ttcgcaaagc gaggcaatgt ttccatgttc caggcgatag cattcggcaa
  1248541 tcgtctgata ggaaatgtcg ggatcacgca tgacggactc gtcgagccgc agctcgctca
  1248601 gcatatgatc gaccagcgtt ttccaggagg gcaagccgac actcatcgac acgcccgctc
  1248661 cgacaaacag caccgcatgc cggcgcttca gcgccgaaac gatctgctgg atgtgctcct
  1248721 tcatattcgc tcctgctcag gagcgctcaa cacacgagtc gcaaagatgt tccaggctgg
  1248781 ttttccgacg aagatttcac cggcggtttc ccgcctttgg agcgtccgcg cgcacgggtg
  1248841 gatccggcgt ggcccattcc gccgccgcga tcgccgagcc aagcaggagg gcaggtaaag
  1248901 cgagcgctga aaagaaccgg aggacgtgac ggcgacgctt gcgcctttta tcccgatcgt
  1248961 ggaccacctt ccgccccctt cgccagatgt gaaacagctg catatgatag aagcagagat
  1249021 gccgtgaaag tcgagttccc agagtaacac aactttgtgt ctgcaacgtc acgtccggag
  1249081 gccggctcct tccgggagtg cacaagcatc tgcgatcacg atgaaccaat ttcgttctcg
  1249141 cgagttccac ttacgagaca atcaaacatg gaggacgact catggactgg aatcgtgtgg
  1249201 aaggtaactg gaagcaggtc aaggggagga tcaaggagca gtggggcaag ctcaccgatg
  1249261 atgatctgga tcagatctcc gggaaccgtg atcaacttga aggtaaaatc caagagcgct
  1249321 acggaatcga gaaggaccgt gtgcggcgtg acctagacga ctggtacggc cgccagactt
  1249381 gggattggtg acgagcggga cggagatccc gccagagcgg gatctctttc ccaaaccgat
  1249441 cctcactgaa aggagacgcc aatgaaggtg ccccacaaag aaaaggcgct ctcgcgcgac
  1249501 gaggattatc gcgactatga ggagcgcgat cttcgtgaag gctggcccta ttcagacggt
  1249561 agcggtagta cctcgcgcag tcctgaaaac ggaagctatg gctccaccgg cgcaaatttt
  1249621 gatgaagagc gcggtgaggg cttcatagtc gatgatgccg gtgcagatgg acttgaggaa
  1249681 aatcccgtcg acaacgggcg ctcccttcca acgaaccgca tcgacagcga cgaactggaa
  1249741 gcggtcatta cggaccggct gacccaaaac gatgaaacgg aggccaacgg catcgaagtg
  1249801 cgtgccgtaa acggcatcgt cacccttgaa ggtgctgtcg aaaccctgga acgtgcacgt
  1249861 cggattcagg ccgtcgtgga ggctgtcgca ggggtactgg aggttcgcaa caatctgcag
  1249921 accctgggcg tggattcaca catcccggac gacggctagg cagcaccgtt tctttgcgcg
  1249981 tggcgccggg gattgatgga ggagccgatg gcaatcttcg aggtgttggc cgacccggag
  1250041 ctggcccagg aactcggcgt ggccgtggcc atgctgaccc gggacgaagg ccgtgatcgc
  1250101 cctcgcaagg ggatcatgct gacccgcgaa ctggttgaag atgcgttcga aggtgatcgc
  1250161 gaacgggcgg ccgaagcggc gagatccggc ttgatagacc aggaggcgat gcgccgaatc
  1250221 gacagccctg acaggctgac ctatcagcca cgtggtcagg ccggtcaagc ggcatgggtg
  1250281 cttgcggctt tcacccgtga cgatctggga ttgtttgaag ggccagtccg ttccggcggg
  1250341 gccggggcgg gtggaatcac ggcctgaagc acacccgctt ttctccggat cacgaaattg
  1250401 ctctggcttc ttgtttttca gcaattccgg gcggaaatcc gcaaagattt tttctcatcc
  1250461 cgctctccaa aattccgccg cccacgttgg ttgataggga acaatcctgc caatccgcgg
  1250521 ttggctgccg gaagggacgt tcgaatggag aacatccgat gaagggtatc cttatcagga
  1250581 gtgcgatcgc cgtaagcctg ggggtagcgt ccaccccggt cttatcgcag acggagcagc
  1250641 cggcgcaggg ccagtcgagc ggccaatcca ccgactgccc ggccggcacg gaatgtccgc
  1250701 aaggcggcac gcagccggac cagcagcctg acccccaggg gggtgcaaca cagcaggggc
  1250761 agaccggcca ggaccagcag caacagccag ctgatcagca acaggatcag caaggccaat
  1250821 ccgatacaaa gcaggatcag ggcggcacgc aaacgcaaga gcaggggtcg gacgcgcaga
  1250881 cccagcagca agattcggaa cagcagcctt cgcaaggcgg aaccgatcaa ccggctcaag
  1250941 gagagtcccg ttcgaccgag cagggtcaga cttccggctc ttccggaaac gtggacgtga
  1251001 cgatagagca gaagacggaa atcacgcagg tcatcaagga agagaacgtc gacccgatcg
  1251061 acgtcgactt cgatgtgtcc gtcggcgtgg cagtaccgga gactgtcaag gtcgagctgc
  1251121 aaccggttcc gacccgaatc gtacagatcg tacccgaata cgaggggtac ctgttcttcg
  1251181 tactggcaga cggcaggatc gtcattgtcg aaccgtcgtc tctagaaatc gtggtgatcc
  1251241 tttcctagac gatttagttc cgcatctgac agacctgatt cagggtccgc cggctttttc
  1251301 cgggcgggcc cttttttctg ccctccgtcg atcggacgtg tactgataga ccgcaaagcg
  1251361 cttcaggccc tgggctccgt attgtgttgg cgccagatgt ccagaagcag cagcgtgacg
  1251421 gtgaaggcga ccggcccgat caccaaccct gccgacccga atacgatgat gccgccgatc
  1251481 atgctcatga aggccgtgag ggtgtggagc ttcaggcggt cccccacgaa gatggggtac
  1251541 agaagattgt cgatggtcgc gaccaccccc gcgccccaac cggcgagtat caacgccttt
  1251601 ccccattcgc cgctcaacgc cagcgatagt gcggccggta gccagacgat gaaagcgccg
  1251661 agcaccggta cgaccgcgag caagcccatg gcgagccccc ataccacggg cgccggtaag
  1251721 ccgagcaacc agaacatcag gccgcccatg gcgccctgca cggctgcaac ggccactgtg
  1251781 ccgaagacaa cggcatgcac cgtttcgtgt acccgcgtga acagccggtt catatcctgc
  1251841 tcgctgagtg gggaatgttc cttcagcgcg gccagcactt gccggccgtc acgcatgaag
  1251901 tagaagagga aatagaatgt caggacggca tcgatgatct gggcaacgga accgcgtacg
  1251961 aacgaggcgc tgaagttggt aagccagctg gtggcgcttc cggcgatccc ggccagatcg
  1252021 agctgcgtct cgatccagac gacggccggc gcgagacgtg gataattggc gagcgcgtcg
  1252081 cgccaggtgc cggaccgcag cgcctcctcg atgatctttg cgcccttggc agcctcgttt
  1252141 accaaccgct ccgccatgaa ggtaagcggc acggcgacga cgaagacagc gatggcgacg
  1252201 gtcgccgcgg ctgctgcgtc cggatagcgg aagcggcttt tgacccggcg atgcagcggc
  1252261 tggaacatca cagccaacac gagcgcccag gtgagggctg gcaggaacgg tacggtgagg
  1252321 aacgtgcaca cgaccaatcc tacgagaagg gcgacaagga ccgccaaagt gcgcgagcgg
  1252381 cgcggcgtaa aaaggcggtt cgagttctcg tcttcgtccc gcacgggaat actcttcgcc
  1252441 atcgcgtctc tcgccgttgc agccgtctcg ggtccagcga ggcagccttg tcaaggataa
  1252501 cgattccaga gcgaaagacg ttgcgaacaa ctaagaaaat gagcgcatga agtgcgtgtt
  1252561 tgccgcgcaa cacctcagtc ttggcgcgga gagggcacta cacgagactt tgaacatggt
  1252621 ttgatagcgc aatcaggatc ggtgctggag aattcgtgcg gggcggccgg gcgaattgcg
  1252681 atggcgcatt ctggcgcctg cgcggtctcg gtttggcgaa aacaggacgt ttgcacatgt
  1252741 ctttcagacc acttctcggt aatggtcgga tccggactgc gggtgagcgg ctggcgaagc
  1252801 cgttgacagc ttcgtgggcc aattcatcga tcattttcga tcgccgccgc tgggcatgcc
  1252861 gggaagcgga aatgcgctgg accgctccgc atcacctgtt cgttctgact gagcgaggcg
  1252921 gcacatccca gacgctcatc cgttccgacg ggagcctgta tcaggggcgg gacggaccgg
  1252981 gtgccctgac attcgtgccc gcgggcacgg aacggctcgg cgcgtatcgc gacgtcgatc
  1253041 tcacctattc ggcgctctgg atcgatcccc ggtccatccc tccgggcagc gatcacctga
  1253101 agaacctgcc ggtcctgata aacaagagtg actttgtcac ggaagcgctg ctgaaatcgc
  1253161 tgagttgcga gatatcccgc ggccacgctc ccgatacggc ctatatggag catctggttg
  1253221 cacttatcgc tttgcggata cgttctgtct ttgatgaacc cgtaaaggtt atccgccacg
  1253281 gatcccttgg cggcgccgtc gtgaagcggg ttcgcgacta tatcgacgcc catctggacg
  1253341 gagacatttc gcttggcgag ttggcgcatg tcgccggtgt tgcggcggat tcctttgcgc
  1253401 gtcgcttcaa ggccaccaca ggccttgcac cgtacgccta tgtcatcgag gaacgcgtcc
  1253461 ggcgggcgga gtccctcctg catgaaaccg acatcgcgct cagcgagatc gcattgaatt
  1253521 gcggcttttc gagccagagt cacttcaccg ccacattcaa gcgcctgcga gggataacgc
  1253581 cgcgcgctta tcgatcggac gttattccgg aattctgata cttccgccga tttcctgaaa
  1253641 gaaatgttac gcgtccagcg ccaacttgtg tcgcgtcgat gcacgctgcc ggctgcaatg
  1253701 caggcggcga gtatcctcct caacaggcaa accggagatg acacatgcca gaaaagcaaa
  1253761 aagaaactgg cccgacgcga cgggcgcttt tggagggcgg ggcagccacc accatgctcc
  1253821 ttgtcgccgg gctgccagtt ggacgttccg cggtcgccgc cgttgctgct gaacccacag
  1253881 taaccccgat gcccacattg ccggttatgc tcaatatcaa cgccagaaat atagcggtgg
  1253941 aagtggatcc gcgaacgacg ctgctcgaca ccttgcgcaa tcatctcggg ctcaccggtt
  1254001 cgaaaaaggg ttgcgaccat ggtcaatgcg gcgcctgcac ggttcttgtg aacgggcgcc
  1254061 ggatcaatgc ctgtctgtcg ctggctgcca tgcatgaagg cgatgaaatc accacgatcg
  1254121 aagggcttgc agccgggggc gaacttcacc cggttcaggc ggctttcatc gaacacgatg
  1254181 gtttccagtg cggctactgc acgccgggcc agatctgctc cgcagtcgca atgttgcgag
  1254241 aggcgaagga cggttggccg agccatgtga gcgcggatgt tggcgccgct cccgccgcgt
  1254301 tgaccgacac cgaaatccgc gagcgcatga gcggcaatct ctgccgttgc gccgcctatc
  1254361 ccaacatcat cgccgccatt cgcgatgccg cagaaaggtc atgaagcatg cagcccttta
  1254421 cttatcagcg aagcgaagac gcggcggggg ctgtggcggc cgtcgcggga agaccggcag
  1254481 cgcgtttcat ctccggtggc accaatctgc ttgatctgat gaagctggac atcgagcgcc
  1254541 cgcagcatct cgtggacatc agccgattgc cgctggaccg tgtcgagccg acggaggagg
  1254601 gcgggttgca tatcggcgcc caagttcgca atagcgacct cgccgctgat ccgggcgtca
  1254661 ggtcgcgcta ccctattctg tctcaggcgc tgctggcggg cgcttccggc cagatccgca
  1254721 ataaggcttc cactggcgga aaccttctcc aacgcacgcg atgcccctat ttctacgata
  1254781 gcaacatgcc ttgcaacaaa cgggagcccg gcgccggctg cgccgcgctg aggggcttca
  1254841 accgaatgca tgcggtgatc ggagcgagcg attcatgcat tgccgtgcat ccgtccgaca
  1254901 tggcggtggc catggcagtg ctcgatgcaa gggtcgaaac agtgtcaccg ggaggagaaa
  1254961 cgaggtcgat cccgctcggt gacctttatc tgctgcctgg gacaacggcg gacgaggaga
  1255021 cggtgctcgc ccatggcgaa atgatcactg gcgtcactct gccgccgccg ccggcgggcc
  1255081 ggcaggtgta ccgtaaggta cgcgaccgtg cctcctatgc gttcgccctc gtttccgttg
  1255141 cagcgatcat cgaaacttcc ggcaatcggg tgcgaagcgc ccgcgtcgcc atgggcggcg
  1255201 tggcgccgaa accctggcgg gcgcccgagg tcgagagcag gcttgccggt tcggctcttt
  1255261 cggatcaggc cttatcggag gccgccgagg cggctctccc cgaagccgtc gggcatggcg
  1255321 gcaacgactt caagatacgc ttggccaagc ggacggtgcg ctacacgctc gccgccgcgg
  1255381 ccgaactggt ttgacccgaa aaaattggtg gaaacaatga cggaaaatgc gcagcgacgt
  1255441 cctacaagcg gcggcgacca gttcataggc aaagcggtcg accgcgtcga tgggccgcgc
  1255501 aaggtcaccg gcaccgctcc ctatgcctac gaaattgcgg agggcccgct tccggcttat
  1255561 ggctatattc tcggtgcggc cattgccaaa ggacgcattc tggaaatcga cgcggaactc
  1255621 gccgaacgag cgccaggcgt cctttacgtg atgacgcact tgaatgcgcc gcgccaaccg
  1255681 gaattcggcc cggccgtcac gccggccgta cgcgaggttt tcacccgtgc gcgacccgtg
  1255741 ctccgtggcg atcacgtgca ttactacgat cagcccatcg ggctggtggt cgccgaaacc
  1255801 ttcgaggcag cacgtgccgc ggcggccctc atcaagatcc gttaccagga gactgccggc
  1255861 gacttcggtc tcgaagagca ccttgccgcg gcctatgcgc ccaagcggac caatgcaggc
  1255921 ttcgagacgg acagcgcggt tggtgatttc gaggcggcat tcgcggaggc agaggtgcgg
  1255981 atcgacgtga gctaccgtac gccctaccag catcacaatc ccatggaacc gcatgctacc
  1256041 ttggcaatct ggcaggggga cgatgtaacg atccacacct cggcacagac tctctcgaac
  1256101 ttccgtgcag gtcttgccgc cacgctcggc gtcccggtcg agcgagtgcg tgtggttagc
  1256161 cgttatattg gtggtggttt cggttccaaa ctgatcgtcc atgccgattc ggtattcgcg
  1256221 gccctggccg cccgtatcct taaaaggccc gtcaagatta ccctgacgcg gcagcagatg
  1256281 ttcgccaatg ccggtcaccg tgcggaaatg ctgcagcagg taagattggg cgcgcgtgcg
  1256341 gatggcaggt tgatagccct tgggcatgac gtctggtccg ctaccgcccg cgtcgaggag
  1256401 ttctgcgagc aaacagcggt ttttgcccgt tcgctctacg ccgcatccaa tcgcctgacc
  1256461 cgacaccggc tcgttaccgt cgacctcaac cgaggcgaat ggatgcgatc tccgggtgag
  1256521 gcgcccggca tgctcgcgct ggaatgcgcc atggacgaac tcgccgaaca cctggatctc
  1256581 gacccgatcg agctcaggat tcgtaacgag cccgatcagg atccggaacg ccgggtgccg
  1256641 ttttccacgc gcaacctcgt agcctgcatg caggaagggg cgcgtcgatt cgactggggg
  1256701 cggcgcagcc cagaaccggg ccgccttcgc gaaggacgaa agctggtggg gatgggcatg
  1256761 gccgctgcga tccggccgaa ctacatcgga gccgctgcgg cttgggtccg gattgatgcc
  1256821 gagggacagg tgaccgctcg ccttgacatg accgatatcg gcaccggcac ctacaccatc
  1256881 ctgactcaga ttgccgccga tactctgggc gttccccttg ctgcaattgc gatcgaactc
  1256941 ggcgacagcc gctttcctct gacggcgggc tccggcggat cctggggggc ggcgagcgcc
  1257001 ggaacggctc ttttgcgtgc gtgtgaagcg ttgaaagaga aaattcttgc cgccgcccgc
  1257061 gtgcatggcg cgccggttcg gaatgccgcc gacgtttcga tggcggcggg agcggtgcgg
  1257121 ttcggcaatc gggctgagga cctgaaggac gtcttacgcc gggtcgcacc cgaaggtctc
  1257181 gacgcccggg gttcggtcga ggcgggggcc ggcacagagg cctaccaggc attttcgcag
  1257241 cattcatatg gtgcgcattt tgccgaggtc agcgttgact gcgacacggg cgagatccgt
  1257301 gcaaggcgcc tgctcgccgt gatcgacgca ggccgtattc tcaatacaaa gacggcgcgt
  1257361 tcacagattc tcggaggcat gacctggggg ctcggcgcag ccctgatgga aaaaaccgtg
  1257421 ctcgacggcc gctacggaca tttcgtcaat catgatcttg ccgaatacca tattccggtc
  1257481 aatggtgatg tccccgatct cgatgtcgtg ttcctcgagg agaacgacga caaggccaat
  1257541 cccctcggcg ccaagggcct aggagaactc ggcgtctgcg gggcgggcgc ggctatcgcc
  1257601 aatgcggtct ataacgccac cggggtgcgg gttcgtgagt tcccgctgac attggacaag
  1257661 ctgctgccgg gcctacctgc atttgtcctt taatcggaga cgatcaaagg acaagaacat
  1257721 gcagcaaatc atggtgctgc ggcggtcttt gttgtcgtaa atcacgaacg tcgctgtagt
  1257781 gaccgttgcg ttccgagcgc cggagccgtt caggtaggcg tcgagcccat cacaagacct
  1257841 tcgatgtcgt gtttctgcgt gacggggatc agctcgtcga cgatcctgca gacgaggtgt
  1257901 tgcttcacca gtttcggtag cgcgtcgtag tagtcctgcg tcaccatcat gtcgtgcagt
  1257961 tcggcatggc cggcgccggg cgcgtcgacg ccgaggacca tgacagggcg ggcgatcggc
  1258021 gaagcgtgtt ccgtcccgcg atggatggtg agcgcggacc ggcatgaaac atcgccgagc
  1258081 ctgggatatt tgcgtgtcgc gagcttttga aactcgggcc acctttcctt gggcgggaac
  1258141 atttcatgtt tccactctct gccgtcgagc cactgggtgc cgggtgcgat ttcgaacggc
  1258201 cccatatcct ccgtcacgtc cacgccggtg aggttgaagg cgagcgaggt gatgcggcgc
  1258261 tcgacatagg tctcgggcgg cgaagggaag tcgcggtgcc agggttggta cttcgctccc
  1258321 tgaaaaggta cgtcgaaacc gatctcgacg atctgatagt ccggaccgag catcgcctcg
  1258381 catatgccga cgacccatgg gtgggtgacg agatcgacga agccggaaaa gtcctgcgga
  1258441 tggatctcca cataccagcg gcgcggcccg cgaccgacgg cgccgcccgg ccgctgaatg
  1258501 gccgaccaga aggccgtcat catgtcttca cgcatcgcct ccgcccattc gcgcgagaag
  1258561 gcgcttttga ggccggtaat gccttcgcgc tgcaaggctt cgacggacgc gtcgaggtca
  1258621 tagccagggc tcgtttcgcg tgttgctgtc gtattcattg cttgtcctct tgctttctct
  1258681 ttgtcgcggg cgtcacctgc acctcagacg cgtccctcac tcgcaccgcg cgacatcaac
  1258741 cgcgcctgaa gaacgacgac gacgagcagg aagccgccgc ggatgacaga ctgccaatag
  1258801 gccgaaaggg aaatccaccc gaggccattc tcgaaattca ggatgttgaa caccattgcg
  1258861 agcagcagag ctcccgcaag tgttgcgccg acggacccgg aaccgcccgt caggagcgta
  1258921 ccaccgacga ccaccgaggc gatggcgaag agttcccagc cgaccccctc ggtaggctgg
  1258981 ccggcgccga attgcgaggc aaggatgacg cctgcaagcc ccgccagcgc gccggagccg
  1259041 atatagacgg cggcgagcgt tcgccttacc ttgaggccca tcaatgcggc cgtcgcctcg
  1259101 ccgtcgccta tggccagaac atggcggccg acgggcagcc gttctagcac cagccagccg
  1259161 gcaaaataga cgagaagggc gatccaggcg ggaatgggga agcccaggaa gtcgtcctgg
  1259221 ccaatcgccg tgaagccgct gtcataggaa acggagaccg actggttacc cgccagcagc
  1259281 aaagcggtgc cataggcagc aagcatggtt gcgagcgtgg cgataaaggg ctggatgcgc
  1259341 atcacggtca cggtgaagcc gttcagcgcc ccgacggcaa ggcccgccgc aatgccaccg
  1259401 aagagacctg cagcccagtg atagggcgat agaagcgccg cgacgacgct cgccattgcc
  1259461 gcggtgccgc cgaccgaaag atcgataccc cccgtcatga tgacgaaggc catgcccagg
  1259521 gcgatcagcg caaacatcga gttgtaacgc agaaagctca ggatgttgta ctgtgagagg
  1259581 aagttctcgt aacgcagggc gccgaacagg atgagaccgg cgagcgcgag aatgacgccg
  1259641 agccgggcca tgtccccgga agacttcagc gcaaaagtgt tacggaaggc gttcatcgtc
  1259701 attctccctc acggttttcc ggcacgctgc tggatgaata ccgcaagcag gatcagggca
  1259761 gccttgacga tcagcgcagc cgcgtcgggc acaccatttg caagcagggt gtagcgcacc
  1259821 agctggataa ccagggcgcc gatcaaggtg cccatgatgt tcgcgcgccc gccggtcaga
  1259881 agcgtgccgc ctacggcgac ggcggcgatt gcgtctagtt ccatgccgag gccgacaagg
  1259941 tttgcatcgc ttgcggaatt ccgcgcgacg acgatgaggc ccgccacgcc ggcaagcgcg
  1260001 ccgctgatca tatagacgag cagtttgacg cggtgcacgg ggataccggt cagccgggct
  1260061 gccttctcgt tgcccccgac cgcgatgacc tggcgtccaa aaaccgtgtg gcgaactgcc
  1260121 gcccatgcga tcgccgcaat cacaatcatc aaaattacct gggcgggaat gccggcaatg
  1260181 cgcccgagag ctatgaattg gaagccttcg ttgcggaaga cctgcaggtt gccgttggtc
  1260241 atgacctggg cgatgccgcg gccggcaatg aacaggacga gggtggcgat gatcggctgg
  1260301 atggcgaaac gagtcaccag cagcccgttg aacaaaccga gcagcgccgt ggcgatgacc
  1260361 ggcagaataa aggcaagtgc cacggcgacg ggcatggacg aaaccggaaa cagcgcgccc
  1260421 ataaagatca tcggtgcaag cgcaccgcct atcgccatca gtgaacccac cgaaaggtcg
  1260481 atgccgccgg tagcaatcac cagtgtcatg ccggtggcga cgatcacgat cgtggcgacc
  1260541 tgggtcaggt tgacgttgag cgtctgcaaa gacaggaagt ttggagtgaa gaggacgttg
  1260601 aagaggatca gtgcgaggaa cgcggcgaca gtgccgtatc gtccggccag tgtgaagaag
  1260661 cgtttgccgg aggggacggt gcccgcggtg gcctgtgtct cgatcgtcgt catgctactc
  1260721 cacctgatgc gccatggcgg caaagagcgc tgcctcgctc aactccctgc gcggcagaac
  1260781 cgccaccgag gttccatcgc tgaggacggt tacccggtcg gctgccgcga gcaattcctc
  1260841 gagctccgac gaaatcatca gcacgcccaa accctcgtcc gctaacctgc gcaaaaggcg
  1260901 gagaatttcg gctttggcgc cgatatcgat gccgcgagtc ggttcgtcga cgatcaggag
  1260961 tttcggatcg gtgcagagcc atcgtccgag cagcaccttc tgctggttgc ccccagagag
  1261021 ttccttgata ggctggtcgg gcgaagtgca tctgatccca agcgcggcga tgtagctcgc
  1261081 gacgatctca tcctggcgcg cgcgatcgac aatgccgcta cgggcgagct tcggcagaag
  1261141 cgcgagcgtc atgttttccc ggatgctcat atccggaatg atgccgtcga ccttccgatc
  1261201 ctcggaaacg agaccgatgc cgtccgcaat ggcttccgcg ggctgacgat aggatcgcgc
  1261261 ttggcctttg tagcgaattt ccccgcgctc aagccggtcg gcgccgaaaa tcagattggc
  1261321 cgtttcggtt cggccggagc cgagcagacc ggcaagcccc gagatctcgc cttcgcgcac
  1261381 cgtcaggctg acattccgca cccgaacgcc ggccccggca ttctcgaccg ataggcgcac
  1261441 cggccgctgc gcgccctcat ccgcatcctt ggcaatcgct tcgaaggcag cgagctcctt
  1261501 ccccagcata tggcgcacca gtgcgagctt cggcatctcc gccatcgcgc ccgtcgccac
  1261561 cgtcttcccg tcccgcatga tcgtaacgct gtcgcaaatc cgatagagct cgtccagacg
  1261621 atggccgatg aagacgacgg atacgccgcc gcgtttgagc gttctgatcg tttcgaaaag
  1261681 gatggcgacc tcgcgctcgt caagggaaga ggtaggctcg tccatgataa cgagacgtgc
  1261741 cttctgagtg acggcgcgcg caatcgcgac catctgccgg gtcgcggcgc tgaagtgggc
  1261801 gaccggctga tcgacgtcga tctccaggtt gaaggtccgc aggacggcga ccgcgccttc
  1261861 gcgcattgca cgcctatcga tcaaaccgaa gcgccggggt tcgcgcgaaa gatagatgtt
  1261921 ctcggcaacg gagcgttgcg gggcgaggtt gatctcctgg tagatcgttg caatccccct
  1261981 ggcctggctc tcggccggca tgttgaagga aacgtcctct cccgcaaagg cgatcgaacc
  1262041 ctcgtcgcgc cggtacgcgc cggtcagtat cttgataagc gtcgactttc ctgcgccgtt
  1262101 ctgaccaacg agcgccatca cctcggcttc gccgacttca agtgaagccg agcgaagcgc
  1262161 gggaatgccg ttgaaggatt tgcagatgcc gtgcatggac agaagcatga aacctcccga
  1262221 tgccgatctg tctggtcgcg actgtgggaa acgcgcagga tcaccgaacc cgttgatcgg
  1262281 ccggcatggg ccggccgatc aagaaggatg tcagtacgcg ttggcgagtt cggcagccgc
  1262341 gttggtcgag tcgtagaact tgtcctcgtt tatgaccagc gggtcgatct tctcgccctt
  1262401 ggcgtaacgc agcatcgttt cgaaggcctt gggtccgaag cgcggattgc attcgacgac
  1262461 tgctgcgatc ttgccgtcga tgaccgcctg aaccgcttcc ttgccgccgt cgatcgacaa
  1262521 taccagcaca tccttgcctg ggaccttgcc ggccgcctcg atggcagcga tggcgccgat
  1262581 cgccatttcg tcgttatgcg cgtaaacgat gtcggcatcc gggtgcgcct gcaacagggc
  1262641 ttcggcaacc tgccggccct tgtcccgggc gaaatcgccc gactgcgatg cgacgatctc
  1262701 aaagccgcct gccgttttga tcgtctcgtc gaagcctttc ttgcggtcgt tggccggaga
  1262761 cgaaccggtg gtcccttcga gctcgatgat cttcgacttg ccgttggcgt tcttgatcag
  1262821 ccactcggcg atgcgcttgc cttcctctat gaaatccgag ccgatgaagg tgacgtagtc
  1262881 ctcgcccgcc ttggcaagcg acggatcaac acttcggtcg agcaggatga cggggatgcc
  1262941 ggccttcttg gcggccatga cggcggggat gagcggtttt tcttcccgcg gtgcgaggaa
  1263001 gatcaggtcg accccctggg cgatcatcga gttgacgtcg gccacctgct tggcagcgga
  1263061 tccggcagca tcggtataga ccagctgatg cccgagcttc tcggcctcgg ccttcatgct
  1263121 gttggtctgt gcgatgcgcc aggggttgtt ggattccgtt tgcgcgaagc cgaccttgta
  1263181 ggtctccttc tgcgcgagct tcggcagttc cgcgaatgcg acagtcccgg cgacggcgat
  1263241 tgcgccagcc gcggtcgcgg caagcatgaa cgcgcggcgt gaaatcctgt tcatggtgtt
  1263301 ctttcctccc ggtttgccgg tattcctcca ccggctgcga gcaagtttat gcttcacacg
  1263361 gaaaaacctt gcgctaatat tattagcagt caaggctaaa gttattagca catgcacaaa
  1263421 ttgaatgcgg cgctgcagcg ccgggtaggg gagcaaaatg ggaaagggca acggagacaa
  1263481 cgggtcgccg aaggatgcgg gcggcggcag gcctaccatg accgacgtgg cgcgtatcgc
  1263541 cggcgtctca cagtcgagtg tttccctcgt gctcaacgag atgtccggag cccgcatctc
  1263601 ggccgagacc cgggcgcgcg tgcgcgacgc ggcgcgcaag atcggataca ggttgcccaa
  1263661 cacacgccag gacctcgacc acgctcccgc gatcgaaaaa gacacgatag ccttcatcgt
  1263721 cgacgagata tcgacaagtc cgcatccggt ggtcagcctc gacggcattc gcgactatgc
  1263781 cttcgagcag ggcctgctcg tctctgccca cgccactcgc tcaaatccgg acctggagag
  1263841 cgccgtccta cggtccgtcc ttcgagatcc ggcaatcgcc ggcgttattt atgcgacgat
  1263901 cttcacacgg aaggtgagcg tgccgcgcga attggaaaac gtcccgacga tcctgttgaa
  1263961 ctgctatgcc gagccgcgcc agcacatggc gatcgtaccg ggggaggttg cggggggctt
  1264021 cgcggcgacc gcgcatctaa cgtctctcgg gcaccggcgc atcggcttca tcaacggcga
  1264081 accctggatg gacgccgcta tcgaccggct caaaggctac aagcaagcct tggcgaccgc
  1264141 cgatatcgct tatgacgagt cactcgtgcg caacggcgac tggctgccat tgcgaggcta
  1264201 cgaggccgcc ctggagctgc ttgcgatcga caatccgccg accgcaatct tctgcggcaa
  1264261 tgatctgatg gcgatcggcg cgctcgaggc agcgtcggag cggggcttgc gcgtgccaca
  1264321 ggacctgtcg gtactcggct acgacgatca agagctcgct cgctacacgc atccgccact
  1264381 gtcgacgctg gtgttgccga actacgaaat gggccaaaag gccgcggaaa tcctgatcga
  1264441 catggccata catggaaaga acccgcgccc gatgacgatc aaggtggatg ggcctctcgt
  1264501 gaaacgaggc acgacggccg ccgtccccga gaggatggct ggacgtccct ttgccttgcg
  1264561 cgaggggtga gccgctccac ctctttgcaa cgacgcgaca agccttttcc caaagtgcct
  1264621 acttcagaaa atcggcgcgg tgtggcgtga agctgtcgat cagccgaccg gcgtccagcg
  1264681 ccctaacacc atggaccacg ccggaaggtg cgatgaaact gtcgccggcg gaaagaacct
  1264741 gcgtttgttc tccgaccgta acttcgaacc tgccctcggc gatgtagctc gcctgcacat
  1264801 gcgggtgcga atgcggcgcg ccgatgccgt ctttctcgaa ggcgaattcg accagcatga
  1264861 gctcgtccgt atgcaggatc acccggcgtc ggttgccttg tccgagttcg acccattcgc
  1264921 cttcggtgct tcgagcgaag agtttcgtat ccattgtcat ctcctatcgg gcgagccagc
  1264981 cgccgtcgac cgggacgacg gctccgtgca tatagtcaga ggcgggtgcg agcaggaaca
  1265041 ctgccgcatc gccgatatca tcgggcgtac cccaacgtcc ggcaggaatg cgctccagaa
  1265101 tggcggtgct gcgcttttcg tcggcgcgaa gcgcttccgt gttgttcgtg gtgatgtagc
  1265161 cgggggccac ggcattcaca ttgacgccct tggccgccca ttcgcaggcg agcaatcgtg
  1265221 tgatgccgag cgctccgtgt ttggatgcgg tgtaggatgc aacgcggatg ccgccctgaa
  1265281 aggaaagcag tgaagcgatg ttgacgatct tgccccggct tttctcggca atcacccgcc
  1265341 gcccgaaacc ctgagacagg aagaacagcg aacgtagatt gatgtcgatc acgtcgtccc
  1265401 agtcggtctc ggtgaaatcc accgcgtcgg cgcgacgtat gatacccgca ttgttgacga
  1265461 ggccatgtag cggaccgtgc gcgtcccaca gcccgtcgat gagggggcgg gcggctttgc
  1265521 gatccgcaag atcggtacgg gctggaatga agatcccacc cgcatcagcg actttcttct
  1265581 cggtctcgtc catcgccgag cggcccacgc cgatcaccgt gccgccggcc cgggcgaccg
  1265641 aaaccgcgat accctgtccg ataccggtat tggctccggt gacgacgatg cgccggccgg
  1265701 cgaggctgaa gctcgacggc aggctcatcg aagcgtctcc atcgcaacca tctccacatc
  1265761 ggtatagtcg acattgtcgc cggccatcgc ccagatgaag gcgtagttcg cggttccgca
  1265821 acccgaatgg attgaccatg gcggagaaag caccgcctcc tccctggcca tcacgatgtg
  1265881 ccgggtttcg cccggttcac ccatcagatg cagaatgcgc gcgctgtcat cgaggtcgaa
  1265941 atagagatag gcttccatgc gccggtcgtg cacgtggcac ggcatggtgt tccagaccga
  1266001 ccccggagca agctgcgtca tcccgacgac cagctggcag gttttcacgc cttccggatg
  1266061 aatgaactga aaaatcgaac gctcgttcga tgtggccgca cttccgagat cgagccgttt
  1266121 ggcgtcaccg atgcggatat gacgccttgg cagcgtctga tgggcgggcg cactgagaag
  1266181 gtagaacttg gcgggggcgg cagggtcttc ggaggagaag gtgacttcct cgcccatgcc
  1266241 ggcatagacc atgtcgcgcg gctcgagccg gaagctttcc ccgttcatct cgacacggcc
  1266301 ggggccgccg atattcacgg caatgagctc gcgccgctcg agaaagcgcg ccgtcccggt
  1266361 cgggcggatg gcctcgagcg gtaggggcgc gtcgacaggc attgctccgc cgacgatcat
  1266421 gcggtcgtaa tggctgtagg tcagcgaaat gcggcccgga cggaacaggt cgccaatgtg
  1266481 gaaattcctg cgcaacgcgt cagtgtccat gcgcgcggct gttgctgggt caacggcgaa
  1266541 gcgaatggtg tagtcgatat ggcctgtcat cggctcacgg tccttggatt agagcacttc
  1266601 cagggaacgt ttccgctcct gaaagtacat ggtttcaaaa ggttagaacg cttctctgaa
  1266661 gcagtgaaac ggcctaacgt cggggtgtca cgcgtcgcgc ctggccgcgc cccaggccgc
  1266721 ctgctgtccg ctcaaccggg cgcgatagcg ctcctggctt gcggtcaggt gggcacgcat
  1266781 ggcggcacgg gcagcttccg gattgttccc ggaaatcgcc tgcaggatca ccagatgctc
  1266841 ccgctgaagg cctttctgat attcgcgcga aagcgcgctc tcggttcccc agggagagct
  1266901 gacatcgcaa gggatcgccc gtagaccaag cgcatcgaga acctccacat aatagggatt
  1266961 gttggtcgca gcagcgatcg cccggtggaa ggcaaaatcg ctctttccgg tcgattcgcc
  1267021 acgctcgagc agccggtcga actcgaaaaa tgcctcctga atctgggctt cctgcgcgct
  1267081 attgcgtcga agagccgcaa gtcccgcgct ctcgatctcc agtcccatgc gcacctcgat
  1267141 gacgttgagc gcatgggaaa tcttgttgct ggcgtcgagg ctgatcgcac cgaaggcgat
  1267201 cgtcgggtgg tccttgacga aaacgcccgc accctgccgt ggctccacga ggccatcggc
  1267261 tgcgagtgtc gcaatcgctt cgcgaacgac cgtacggctg accccgaaga attcgctgat
  1267321 cctgctctcc gtgggcagct tctcgccggc ctgtatttca cctttcagaa cctgttgccg
  1267381 gatcgagctt gcgacgcgct cggaaagctt cggtttgcgt tcggtcggaa ggtccatgaa
  1267441 acgtatcacc ctttgaagac ggctggcagc catagcgaaa gggccggaac ataggtgacg
  1267501 agcccaagga cgatcaaccc cgccatgtag aagggccaga tgctgcgcat cgcctcccag
  1267561 acggagattt ttccgactgc gcaggccaca aactgcacgg cccctaccgg cggtgtgttc
  1267621 aggccgatgc cgaagttcag gatcatgatg acgccgaaat gaaccggatc gacgccgtag
  1267681 gccatggcca ccggcaggaa aatcggcgtg cagattatga tggtgggccc catgtccatg
  1267741 aaggttccta gaaacagcat caggacattg agcaaaagga gaacgatgat cggattctcc
  1267801 gaaatcgtgt tcatccagtc gatcagcgct gcaggcactc tcaggaatgc catcagccag
  1267861 gaaaaggcgg ccgccatgcc gatgatgagc aggaccatgg ccgtcgtgcg cacggccgcg
  1267921 aatgtggcct ggacgaaatc gcgccaggtc atctgccgat agacgaagac ggttaccgcg
  1267981 agcgcataga gaacggcgat gcaggaactt tcggtcgcag tgaacacacc cgaacgtacg
  1268041 ccaccgaaga tgatgccgat gagcaggagg ccgggcgtcg agaccagcag atagcggccg
  1268101 accctggcga agccgggaaa gacctccgtc gggtagcccc gccgccgcgc gacgaaatag
  1268161 gcggtcacca tcagcgcggc cgcatagagg agaccgggga ggataccggc ggtgaagaga
  1268221 tctgcgatag agatcttccc gcccgccgat atcgagtaga tgatcatgtt gtgcgacggt
  1268281 ggcagcatca gcgcgatcag agccgccatc gatgtaatgt tgacggcgta atctgcgcca
  1268341 tagccgcgct gcttcatctg cgggatcatg agcccgccca ccgccgctgc ttcggccacg
  1268401 gcggaccccg aaatgccccc gaacaaggtc gcagtgacga tattgacctg gccgagaccg
  1268461 ccgcggatgt gtccgacgag cgaggccgca aaggccacta ttttctgggc gattccgccg
  1268521 cgcaccatca ggtcccctgc atagatgaag aacggaatgg caagcagtga gaacacgctc
  1268581 atgccggaat tgagccgctg aaagatcacc agcggcggca ggccgagata gagcacggtc
  1268641 gcgaaggacg cgacgccgag gcagaaggcg atcggcgttc cgatcagcat cagcagcgtg
  1268701 aatacgccga agaggatcat catatccatc gcgtcaggcc tttatttgcg cggtttcgag
  1268761 atcggcagca acctccgccg gcggcatttc atcgagaacg tcgtcgatcg gctcaccggc
  1268821 aagccgcagg acgatgcgct ccagggcgaa caagcagatg aggacgccgc ccgcgacgag
  1268881 cggcacgtaa ctccagccgc cggaaatctg cagagagggc aggacggtgt tccaggtgag
  1268941 ggcgacgagc tgagctccgt accagatcat gccgaagccg aatgcgagcg cgacgagatc
  1269001 ggaaatcatg cggagccaga tcttgccgga tttaggcacc acgtagagca gcacgtcgaa
  1269061 gccgagatgg taattttcgc gtacgccgac agctgcacca agaaagatga accagctcat
  1269121 cagcatgacg gcgccgggct cggtccagct tggtgagtcg ttcaagacat agcggcagaa
  1269181 aacctgccac gcgacgatga gcgtcatcgc gacgaggccc acacccgccg tccagagcga
  1269241 gagcgtaccc agccaggaca aaccccggcc cagttttgac aatccgttag acaaggcttc
  1269301 attcccatcg aaagtgggcg ggcagtctgc tgcagaggct tcggcttgtg agcgcgtggg
  1269361 tgctgcaggc ctgcccgtct ggagcaattc caggaaaagt gcgtagcaat tttccgcggc
  1269421 aatacaagag gttagagagc ttccgcaatt cggagaaaag cggaaactct ctaaagcgtc
  1269481 actgtaccgc gcgcacgtcc tcaaccattt tcttcaggac ggcatcggta acgtgctttt
  1269541 cgtagaccgg cttcattgca tcgatgaaac cctgcttttc gggtgtggtg atctgcgcgc
  1269601 cggccgcttc gaccttccca cgcgactcct tgaccttggc agcccagagc tcgcgctgtt
  1269661 tggcgacact gtcctttgcg gcctgcttga atatctcctg atcttccggc gtgagtttat
  1269721 cgaagacggc cttgttcatg acgaatacct ccggaaggat ggtgtgttcg tcgagcgaat
  1269781 agttcttggc aacttcgaaa tgcttggcgg tgtcgtagct tggaaaattg ttctccgcgc
  1269841 cgtcgatgac gcccgtttcg attccggaat agacttcacc gtaaggcatg ggcgtagcgt
  1269901 tcgccccgag cgcggccacc atgtccacga agatgtcgga ctggatcacg cggaacttca
  1269961 agcctttcat gtcggcaacc gaactgatcg gcttctgttt gttgtagaag gaacgcgcgc
  1270021 cagcgtcata gaaggcgagc accaccactc cggcgctttc gaaggccgtc ttgatctggt
  1270081 cgccgatcgc cccgtccatc accttgtgca tgtgctcttc cgaacggaag aggtagggaa
  1270141 gcgccggaac gatcgattcc ttcaccgtac cgttgaaggg ggccatcgag acgcggttca
  1270201 gctcgatgac gccggaacgc acctgctcga tcgtgtcctt ttcctccccg agttgcgcgg
  1270261 agtgatagac ctcgacggag tagcggccgg ccgtacgctc cttgaccagc tcaccgaagt
  1270321 actcgaccgc ctcgaccgtc ggatagccgt ccggatgcgt gtcggatgag cgcagcaccg
  1270381 tctgggcgtt ggctgcattg cccatgaatg cagcggcgac tactagaccc gccgccagtt
  1270441 ttaccaggat tttcatgctt ttcctcccgt tggcatgatg tgatttctca aagccggtac
  1270501 gccttctttg cgagaccata ggcaaggtcc cgcgcaagct cgtacgcttc attctcccgc
  1270561 aggcgatgtt ccgcgaccag acctgcgaga aatgcgcagt cgacccggcg cgcaatgtcg
  1270621 tggcgtgcgg gtatcgacgg aaacgccctt gtgtcgtcgt tgaaaccgac ggtgttgtag
  1270681 aagcccgccg tctcggtggt catttcgcgg aagcggcgca tgccatccgc actgtcgtgg
  1270741 aaccaccatg cgggcccgag cttcagagcc gggtagacgc cggcaagcgg ggcgagttcg
  1270801 cgcgcatagc tcgtctcgtc cagcgtaaag agaatgatgg tcagattgcg ctcgagcccg
  1270861 acgacgtcga gcaacggctt aagagcggtc acataatccg tgcgagtcgg aatatcgaac
  1270921 cctttgtcgc gaccgaactt cgccagaatg gctggagagt gattgcgcaa ggagcccgga
  1270981 tggatctgca tgaccaagcc atcgtccagg ctcatcttcg ccatctcggt cagcatctga
  1271041 gcccggaaca gtcgccgctc gtccgcattc gctttgccca agcgtaccct atcgaaaagc
  1271101 gccgctgctt cgttttgggg aagattggcc gtgtctgccg tggcgtggcc gtgatcggtc
  1271161 gaggttgcgc cgaatgtctt gaagtaggcg cgtcgcgagc gatgggcgtc cagatatccg
  1271221 gtccaggttc ccgtgtcggc gccagtgatc tcgccgaatt tatcgaggtt ggtcccaaaa
  1271281 ccctgaaaat ccggatcgac caccgcgtct ggccggtatg ccggaacgac tcgccctttc
  1271341 cagccgctat cacggatcct ggcgtgccaa tccagatcgt ccagggcgct atccgtcgtg
  1271401 gaaatcacct cgatattgaa acgctcgtaa agcgcacgcg gcctgtattc agggcgtgcg
  1271461 aggcattcgg ccacatggtc gtaaaggcgg tccgcgttgg cggccgaagg cagttcgtca
  1271521 atgccgaaca gctcagaaag cgtataatcg aaccagagcc gcgtcggcgt gccgcggaag
  1271581 agataatagt tctcgcagaa aagtcgccag atcgcgcggc catccgtcgc caccggagag
  1271641 ccgtcaagcg tcggtacgcc gagcatttcc aggctgatgc cctggctgaa cagcattcgg
  1271701 aatacatagt ggtcggggac gatgagaagt tgagccgggt cgggaaaggc ctcgttcagc
  1271761 gcataccagc gtgggtccgt atgaccatgc gggctgacga tcggcaggcc gcttacttcg
  1271821 gcatacagcc cgcgcgccag cgcacgtgtg ctctcctcgc ccggaaacaa cagatctgga
  1271881 tcgatcagtc ccttcattac gctcccgctc ctccaacagg actctatcgc tagagcctgt
  1271941 aaattcactt gtcaacatac aaacttcgtg aatttgtatg atgactttct tgccgcgcat
  1272001 cgggcctcgg tgtaggtata tttcggagga agccgactgg gagcgacgga gatggaaaag
  1272061 acgcgtatcg gcatgatcgg actcggcatg gcggccgcgc cgcatgccaa gagcctgctg
  1272121 gacctgaagg acagggttga gctggctgcc gcctttagcc cgacgccgga caggcggagt
  1272181 gctttttccg agagctatgg tttcaagacg tgcgactcgg tcgaggcgat ctttcgggat
  1272241 ccgtcaatcg cggccgttat gatattgacg ccgccaaaca ctcatctcga cctggtgcgg
  1272301 caggcggcgg aagcaggaaa gcatgtgctc ctcgaaaagc cgctggagat cacgccggac
  1272361 cgggcagaag ccctggtcga cgtggccgcg cgcgccggta taaagctggg catcgtgctt
  1272421 cagcaccgct ttcgcactgt cagcgtggaa cttgcaaagc ttatcggtga ggggcgcctt
  1272481 ggcgagatcg tcagtgcttc ggcccggctc cacaattggc ggccgcaaag ctattacgac
  1272541 cagccgggtc gcggcatgcg ggctcgcgac ggcggcggcg tgctcctcac ccaggccatc
  1272601 catacgctcg accttctcgt ttcgctcgcc ggtcttccgg aagaggtcaa ggcatatgcg
  1272661 acgacaagca gggtgcaccg catggaaacc gaagacctgg caatggcggc aatccgcttt
  1272721 tcaagcggcg caataggaac cgtgagtgca accacctgcg catatccggg ctatccggat
  1272781 gagattgaca ttatcggcac gcgcggcatg gcgcgcctcg gcggacagcg actcgccgtt
  1272841 tccctgcacg acggagccga gctttcgttc gaggacgagg cagcgggtgg ggccggcgcc
  1272901 gatccgatgg ccttcccgca ttgccatcac cgagcggtgc tcgccgactt tctggatgcc
  1272961 gtcgatggtg atcgcgagcc acgtgtcaac ggacgcgagg cactgaaggt ccaccggctt
  1273021 atcgccgcgg ttctcggcgc tgccgaaagc ggcatgccgc agcgcctcta gagcctttcc
  1273081 cttcaaacaa ggctctaggt cgccgcccga ccgatcgccg gacaagcccc ggaacaaggc
  1273141 atttcgctcg acgttgctga tgcacgcagc agaatagagc cttcggaatt cgcgcttttc
  1273201 cgccctacta gagcatcgat ccatgggtac aaacgaagtc gaacttgtcg aaaggctgga
  1273261 tgcagccgag ccgggcaggg ggcgcgctgc ctcagcgccc ggggagatac ccgtcaaagg
  1273321 gatgcgggat gtcttctggc gcgtagtttc cgagatcgcc gaagaaaggg tcgttctgat
  1273381 tgcggcgggg gtaagcttct atcttttgct gtcgctcttc cccgcactgg gcgcgctcgt
  1273441 ctccatatac gggcttgtcg cggacccttc cgagatcggc acgcatatgg gaattctgca
  1273501 ggctcttctg ccgcaggact cctatggctt gatcatggat cagcttaaga ccctgacgac
  1273561 gcagaagcca tccactctcg gaatgggctt ctttataagc ctgtcgatct ctctttggtt
  1273621 ggcggccaac ggcatcgccg cgctcttcga tgcgatgaat gtcgcctatg gtgaaaggga
  1273681 aaagagaggc tttctgtttc gaaccgtcct gtgcatcgcg ttcaccttcg ccgctttgct
  1273741 gttcgccgtg gcgctgatcg tggcgatcgg cgtcgtgccg gctgtgctgg ctcatttgtg
  1273801 ggtcgaccgt tgggtcgaat tggtgaccag ggtggcgcgc tggcctgcgc tgctcctgct
  1273861 cgtgacgttt ggcaccgtgc tcatttatcg tttcgggcca agcagggagc gggccaagtt
  1273921 gcggtggctg aactggggcg ctgttttcag cacgttattc tggtttgcag cctcgtggct
  1273981 cttttcctac tatctggaac acttcgcgaa ttataacgcc acctacggcg ctctcggagc
  1274041 gcttgccggc ctcatgacat gggtctggat ctcggtaatg atcctcatca taggcgcgct
  1274101 catcaatgcc gagctcgaac atcagacggc ggtggattcg acgacgggag aaccgcttcc
  1274161 tctgggcgag cgcggtgctc atgtggcgga tacgatcggc aaggccgcaa actgaccggt
  1274221 tccatatgcg tgcgcacccc tgcacaggca cggagaagga acaaccgtcg ctgttcgtgc
  1274281 attcacaatg agggcttgcg gtgctggagg attatgccat ggcagatcgc gaacttctcg
  1274341 gtctggcggc cagcgcaaag gtcggcggcc atcccatcca ttcgatgctc gttccgtttc
  1274401 cgatcgcgct cctcgtcgcc actttcgttc aggcagtctg gcccggggga ttcctgctgt
  1274461 ctctccttac agttctcctg cttctctaca ccggctggaa aggcggagaa ctcgtctatc
  1274521 atcatcgcat cggcatgcat ccggaagccg aagacggcac cacgccgcca ccggccgtga
  1274581 agcataggac gagacatatc tgaagttcgt cgcgttcaag tgccggcttt cgcggaacaa
  1274641 tcgcccggct aagcggttct acaaagctca aaggagaggt gagctttggt tcaaccgcca
  1274701 gttcgggacg acggattgca aatcgaggaa catcgcactt tccaggagtc tttctggagg
  1274761 gcagagcgcg tctcgtgggt tatcttcggc ctgacgctca tcgccgcgtt actgggtgtt
  1274821 accggttccg gcggcatgtt ggagaggcag atcattaccg tcgccgacgg gtccgttgac
  1274881 gttccgcgat tcagccgctg ggaggcctcg gatgtgctgc aggccacact tgccgggggc
  1274941 gggtctgagc gccgcctgac actttcgccc gaattcttca ggacctttca ggtggaggac
  1275001 atcgatccac cgccgatcgc cgcggaaggg ggggctgacg gtctggttta tcgcttccgc
  1275061 gccgcctccg cgcagcccct cgtcctgacg ctgcatctgc gagcccagta tcccggcatt
  1275121 gtgtcctttc gagcaagcgt caacgacgga cctgcgcaag cgctgcggac gatcgtctgg
  1275181 ccataggagg tatgcgcatg gaatccgtcg ctcgcggtat cacgatctat ttcatactcc
  1275241 ttgtcgcgct ccggctctcc ggccggcgca cggtcgcgca gatgaccact ttcgatttcg
  1275301 ttctgctgct catcatcgcg gagacgaccc agcaggcatt gctgggtgac gatttctcaa
  1275361 tcgtcaatgc agcgctgctc atcctgacgc tgttcggtgt cgatatcgtt ctctcctacc
  1275421 tcaagcagtg gtcgccgaag atcgccttgg tgcttgatgg cacccctacc gtgctcatcg
  1275481 ccaacggcaa cgtcgacgac cgcgcgctga agagagcgcg gatcaatatc gacgacattc
  1275541 tcgttgccgc cagagaacag cagggtctcg cacgcctcga ccagatcaaa ttcgccgttc
  1275601 tcgaagcgga tgggggaata agcatcattc ccaggtgacc gagcctctgc tggctctgcg
  1275661 gagcgtcaga gcctccagac ggaacaagct accgcttggc gtgttcgatt gcatccatgg
  1275721 ccgtccgcct cgggaaacct gatgcagcgg cgtgagaaat ctcggccttt gaggacaatc
  1275781 agatgagttc cggtgagacg agcggatcag gagaccaggc ccgaaacgaa acaaataggg
  1275841 gacgagcggc cgacagcccg ggggaaatcc cggcacgtgg gttgcgcgac gtcttttggc
  1275901 gcgtggttgc ccaagtcagc gaggacagga tttcccttgt agcggcaggc gtcacctttt
  1275961 atgtcctcct ctccgtattt ccggcgctgg cctctctcgt ttccatttat ggcctcgttt
  1276021 cggatcccgg gaccatcgct gagcaggcga gctacctcgc agccatactc ccagcacagt
  1276081 cgcttcagtt gatgacggat caattgaaag cgctggcatc gcagaatacg tcgagtttga
  1276141 gcctcggctt cattggggga ttgctcttcg cgctctggag cgcgcgcaat ggagtatcgg
  1276201 ccctcttcga agcgatgaat attgcctatg atgagacgga aaagcggggc ttcatccgcc
  1276261 tggcgcttct gagcatcggc tttacgctgg ccggtttgat cctgacggct gtgctgatcg
  1276321 gggccattgc cgttctgccg gcattgctct cctttctcga ccttaagctg cagggcatca
  1276381 tcagctttgc gcgctggccg gtcatgctgt tgctgatcgc ggcagtcatt acgctgatct
  1276441 atcgctacgg tccgagccgc gaaccggcca aactccgatg gcttacctgg ggtgcggcac
  1276501 tgagtacggt ctgctggctc gtcgcatccc tggcattttc gtactacatc gacaattttg
  1276561 ccaactacaa tgcgacctac ggcgccctcg gcgcactgat cggcttcatg ctttggatct
  1276621 ggatatccac catgatcgtc attgtcggcg ctgaactcaa tgccgaactg gagcatcaga
  1276681 ccgcgcgtga ctcgacgaca gggccgccca aagcgattgg caagcggaat gcctacgtcg
  1276741 ccgatacggt cggcgatacc aaggattagc tcgctcttag ggctgccgcg gtgatgctcc
  1276801 ttcgtccgca gtcctcggca ggacggccgg cgcgacttcg gtctgcgggg gctccggagg
  1276861 cgtggcagag gctgcgggag gggcggaccc gccgctcgcg gctccctcag gacccgttgg
  1276921 cggagcggct tcactcgtaa ccgcggcacc gatctgtccg tctgtgccca ccgggttcgg
  1276981 cgtcaccctg ccatctgcac cggcaacgcg ccagacagta ttgcctgcgt catcggcgat
  1277041 gaggagggct ccagtcccat cgatggccac gccaaccggc cggcctcgag cctggtcgcc
  1277101 ctcaaggaag ccggtcacga catcctgcgc ctttcctgcg ggccgaccgt tctcgaacgg
  1277161 cacatagacg accttgtagc cgttgaaggt gttgcggttc caacttccgt gctcgcctat
  1277221 gaaggcgccg ttcgcgaagg gctccggtaa ggcagagccg ttggaaaaga tcaggcctag
  1277281 cgccgcgacg tggctggaaa gggcgtagtc gggcgcgacc gccttttcga ccaggtccgg
  1277341 ccgcggcgga tagactcgct cgtccacatg tgcgccgtaa taactccatg gccagccata
  1277401 gaaggcgcct tcctgcacgg acgtcatgaa atccggcacg agattcggcc caagctcgtc
  1277461 gcgctcgttg acgaccgtcc agagcacgcc ggtttcggga tggaaggcca acccgttcgg
  1277521 attgcgcaaa cccgacgcga agacccgcgc ggcccccgtc tggcggtcaa tctgccagat
  1277581 ggcggcgcgg cccttctcgg cttcgagccc gcgctcggcc acattcgaat tcgaaccgac
  1277641 cgaggcataa aggtagcgtc cgtccgggct gagagccagg tccttggtcc agtggtgatt
  1277701 aatcggtccg ccgggaagcg gcgtgaggac ttgcggctcc gccgtgatct ccgcctgccc
  1277761 aagctgatag gaataagcaa gtaccgcgtc ggcggcggcc acataaagcg tcccatcgcg
  1277821 ccaggctact ccgaagggag aatggagacc tgtcagcagg tcgtggcgtt cgtcaacctt
  1277881 tccgtcgcga ttggtgtcgc ggagcagcgt aacaaggttg ctttcctttt cggctccgcc
  1277941 accatcacca tgggccatgg acatgatcca gccacggatc atgtctttcg gccgctcgat
  1278001 cggtttgccc gaaggctcgc gcgattggac gacaagaacg tcgccattcg ggagcgtgtg
  1278061 gacggtcctg ggattgacga ggtccttcgc ataggcagtg ataacgagac tgtccgggac
  1278121 ggcaggcgtc tggtcgtcct tccagccggc gacttcggcg actttcatgt ccggcatgag
  1278181 ctccgatgtg ggctctggga ggactgggtc agggccgatc tgctgcgaaa cgtcaaagtc
  1278241 cgtaccgtcg caaccggcga gcgaggcgag gagaattccg gtcccgacga tggcctttgc
  1278301 accgaaggca gagctattca tgatcgctca ctccgagttt gcgtgcgatg gagcacggcc
  1278361 cggccaagca gggcgacaag gatcgtcaga agcactgtcg ctgcggaaag gatcaaaccg
  1278421 taaggcacga cagccgtcca gccatcgccg gcatggacga ggttgttgac gaaggccagg
  1278481 ccgagcacga gcacgtagcc gacgacatga agccaaaccg acccccgtgc gcgacggtcc
  1278541 gagcgaagca gaaactccac gatcccgacg aggccggata tcacgccgaa agcgatcccg
  1278601 gcaaagagca gccatgcgga aaagttctgc cacatgatgt gccccgtctg ccagaaggcg
  1278661 atgtcggtca gaagggcgag cgtgaaacag acggctggaa acggcacgag caacgaatgg
  1278721 acaggggttg tcacggtcat ggcagtcgat gcggaagtaa ggctcatcgg tgcctcctgt
  1278781 tcggtcggtc gatgaaacct cggccctgcg catttgttcc ttgaggctcc gccaggtggt
  1278841 tcgatcgatc gcgcgcaacc ggggaggtgc aaattggaac catgaagcgt cgaaacagtt
  1278901 tcattgttcg cggcctgact ggcccgtttg gaaaggctag gggaaatgac gggaccgctg
  1278961 gcggcgcata tggccgtgca catcctgctg atgaacatag tggcaccgct cgcagcactc
  1279021 ggactgtcgc gggttctgca gaatagccga gcaatttccg ggcgcttgct gggacttgcg
  1279081 acattggtgc agatcgccgg cctatgggcc tggcacgcac cgcctttcct caaccgggca
  1279141 ctggaatcgt cttcggtaca tttgctgatg aatggcagcc tgtttctgag cgcgttcctg
  1279201 ttctggtggg cagtcctcca tttccgtggc gagcactcct ggcagccggt tgccgcactc
  1279261 ctggtgacca gtaagctcta ttgcctgctc gccgtactct tcgtctttgc gccgcgcacg
  1279321 ctttatcccg acttcgcgag ttcccatttg gggcatgtcg tcggcggtcc gagcaccgat
  1279381 ttgaccgatc aacaactggc ggggctgatc atgttggccg cctgcccggt cacctatgtc
  1279441 ctggccggag tcgtgatcgc ggcacgctgg ctccttgcaa tggagaaaga aggggatgat
  1279501 cccgggtcca gatcaggtgc agaagcgtgg acctgagaaa cctgcactgg acgaacatcg
  1279561 cgaaggttgc ggggctcggc accgggctcc ttatcgtcct cggcgccgtg ttcgtctggt
  1279621 ccggcatcta caacgtcgcc gcatcgaagg accatctgca gatcacgacc tggatcttga
  1279681 cgctgatccg tgaacgatcg atcgccaccc acagtttcaa gatcgaggtg ccggcgctcg
  1279741 atgacgagag caagatccgg ctcggggcgt ctcactacga gggcggatgc gtgccgtgcc
  1279801 ataaccgccc cggcgaagag ataaactcca tagtcaaagg catgctgcca ccgccaccca
  1279861 acctgctgga aatcggcaag catcgcccgc ccgaggagat cttctggatc gtaaagcacg
  1279921 gcctcaaata cacgggcatg ccggcatgga cgaatgtgtt acgcgacgat gaggtttggg
  1279981 cccttaccgc gtttctcgcg agcctgccgg ccacggctgg cgattacggc gagctcgcag
  1280041 gtctttcgcg cggtcagggc aatgcgcgtg aggaaccggc gaacgggcgt gccctcaacg
  1280101 tctgcgtgcg ctgccatgaa cgcgatggca tgagcaccaa cggcgaccgt gtgccgcggc
  1280161 tcgcgggcat gccggaggct tatcttcttc gcagtctcca ggaatatgca caagggacac
  1280221 gcgcaagcgg tgtcatggaa ccggtcgccg acctgctctc cgaggaggca atgcgggagc
  1280281 tggcggcgca ttatcaggcg cttccgcctg tcgccggaac ggccgaacca gatccggagc
  1280341 agctccggcg gggcgaggcc atcgccaggc gcggcatagt gggccaaggc gtgccggcct
  1280401 gtctaagctg ccattccggg cgtcagtcgc agcagttccc ggtgctcgcc ggacagaatg
  1280461 ccgcctacat cgaggagcag atacggctct ggcgtcgcgg tgggcggatc ggaaccccct
  1280521 atggaaggat tatggcggca gtcgccgggg ctctcgacga aggacagatc gaggatgtcg
  1280581 ccgcctacct tgcctcactt cccgcgggac gcgcgccgga cgcgccggtg gcggaggctg
  1280641 gccgatgagc ctcagacggt tcatcgtgcc gatgagtgcc ttcgcagtgc agggttgtgc
  1280701 cggcctgcag tccgctctcg acccgtccgg ggcggaagcc gagcgcatcg gcaccctgac
  1280761 ctggctgctg atcatcttct ctaccgccat tcttgtcgcg gtctgcgtga tcacggcggt
  1280821 cgcgcttttc ggcggcgagc ggtggcgtgc ccgcatctcg ggcgaaagga cggtcatcgg
  1280881 gggtggcctc gcttttccga tcctcgctct cagcattctg ctgggctacg gcttctatct
  1280941 catggctccc ggatccacct cggctcgtgt ggagggcggc ttgcgcatcg aggtggtggg
  1281001 cgagcgctgg tggtggcggg tgacctatgt cgacgagagc ggccggcgca cggaaagtgc
  1281061 gaacgagatc cggctccccg tcgggcgtcc ggtggagctg gaactgacat cggcggacgt
  1281121 gatccacagc ctctgggtgc cgcgcctggc cggcaagctc gacatgatac ccggccgtac
  1281181 caacgtcctg acactggaag ccacggagcc cggcataagt cgcggacagt gtgcagaata
  1281241 ttgcggcggg ccgcatgcgt tcatgtcctt ttatgtaatc gccatgccgg aggatcagtt
  1281301 ttcctcctgg ctttcaggcg aggcggagga cgccttggcg gcgagccggg atcaggcggc
  1281361 ggggcaggcg cttttcctct cgtcgggctg tgtcgcatgc caccgggttc gtgggacgga
  1281421 cgcccagggc acgatcggcc ccgacctgac gcatgtcggc agccggcatt cgcttgccgc
  1281481 cgccaccctt gagaacgacg ttgccgcctt cgtccgctgg atccgcgaag gccagcacgt
  1281541 caagccggaa aatctgatgc cgccatttga aattttcacc gaagacgaat tgcggcagct
  1281601 cgccgcctat ctcgaccagt tgaggtaacg acccatgctc gacttcaccg gccttggact
  1281661 ctggttgaat ctggcgatct tcgccggtgc ggccgtggcg gtctggatgg ccggcgtcag
  1281721 gataaccggc tatgccaatg cgatcagcga gaaaacgggc gtggggcagg cgttcatcgg
  1281781 cgtcgttctt ctgggcggtg tgacttcact cccagaggtg actgtaggcg taacctcgtc
  1281841 gctcagcgcc gatgccagtc tcgcggtcaa cagcatactt ggcggcatcg ccatgcaggt
  1281901 ggcgatcctt gccttcgcgg atatgctgat cgggcgtaag gcactgacct cggtcattcc
  1281961 cgacccggtc gtaatgctcc agggcggttt taagatcctc ctcctttcga tcgtcgcggc
  1282021 ctcgatcgtg gtgggtgacg tgccggtgct attctctggc gtttggatgt ggctgcttgc
  1282081 cgccgtaacc gtcttcgggc tgtgggtcct gtcgcggacg cggcgagaca gaccctggat
  1282141 cgcgaatgac gaagaggtca cgcccgaaaa agaggaggat agggcgcgcg aggcggccga
  1282201 gagcagcaaa aagaaatcgc tgcgcgacat cggctgggcg acggccgcct gtggtgcggt
  1282261 catcatcgtc gcaggctatc tgctctcccg ctcgggagac gccatcgccg acgcgacggg
  1282321 gctcggccag agcttcatcg gtgcggtgct cgtggccatc gcaacgtcgc tgccggaagt
  1282381 cagcaccgtg ttcagcgcca cgcgcgccgg tctctacacg atggcgatgt cggacatttt
  1282441 cggcacgaat ctcatcgaca ttttccttct cttcatcgtc gatctcacgg gtggcgccga
  1282501 tgcggttatg aatggtgccg ggcgattcga ggcctttgcc gccctgattg cgatcacagt
  1282561 cacggcgatt ttcttcattg gcctggtcga acggcgggac cggacgattc tcaagatggg
  1282621 ttacgactca tttgcagttc tatgcgttta cctgtcgggg ctcgtcgtcc tctatttcct
  1282681 gcgcgacgtc agcggcggag gcggatgatg gaactcccca atcccgatcc ccgccccgaa
  1282741 ggagaggtcc gcgaactgga gcgcatctgg gcgacgccac gcggttggcg aatggttacg
  1282801 gccgtcaaca atacggtgat cggtctcctc tatatcggcg tcgcgtttct cttcttcctc
  1282861 atggccggtc tgctggccgt cgtcatgcgc acgcagctcg ccgtcggcga caatcgcctc
  1282921 atcgaccagg acctctacaa tcagatgttc acggtccacg gcacgacgat gatgttcctg
  1282981 ttcgccgtgc cggcggtcga ggctctcggg gtcatgctgc tgccgcagat gcttgcggcc
  1283041 cgcgatcttc cctttccgcg cctcagcgcc ttcgcgatct gggcctatgt ggtcggcgga
  1283101 ttggtcttct tctcaaccat cttctacgac cttgcgccga aaggcggctg gttcatgtat
  1283161 ccgccgctga cgcttatgga atattccccc ggcgacaacg cggatttctg gctgctcggc
  1283221 atcggcttta tcgagatttc cgccatcgcc ggagcggtcg agatcgtcgt cggcgccttg
  1283281 cggacgcggc ccccgggcat gtcgctcgcc cggatgccta tcttcgcctg gacgatgctg
  1283341 atcttcgcca gcatgatcat gttcgccttc ccggcggtga tcctggcgac gatgatgctg
  1283401 gagatcgagc gggcgttcgg atggccgttc ttcacggccg cagtgggggg ggatccgttg
  1283461 ctctggcagc atctcttctg gttcttcggg cacccggaag tctacatcat cttccttcca
  1283521 gccgcgggcc tcgtctcgat gatggtgccg accatggccc gcacgccgct cgtcggctat
  1283581 cacctcatcg tcgtcgccct gatcggcacc ggctttttca gcttcggtct ttgggtgcat
  1283641 cacatgttca caaccggcat tccggcgctg agcctcgcct tcttttctgc ggcaagcatg
  1283701 gcggtcgccg tcccatcggg aattcaggtc ttttcctgga tcgcgaccat tgcggcggga
  1283761 cggcagcgct tccggatcac gaccgcatcg ctgttcatcc tgggcttcct gttcatcttc
  1283821 acccttggcg ggcttaccgg cgtcatggtg gccatggtcc ccttcgatca tcaggtccac
  1283881 gacacctatt tcgtcgtcgc gcatttccac tacgtgctga ttggcgggtt tgttttcccg
  1283941 ctctttgcgg cgatctacta ctggatgcct ctattcagcc gtaggatgct ttctgagcgc
  1284001 gtgggccgat gggtcttctg gatgatgttc gtcggcttca acgtcacctt tctgccgatg
  1284061 catctgaccg gcctcagagg catgccgcgg cgcgtctgga cctatccggg cgagatgggc
  1284121 tgggatacgc tgaacctcat atccaccgcc ggaacctatg tgctcgccgc cggcattctc
  1284181 gtctttctgg tcgaccttgc cgcgaagttt cgcatcggga atagagcggt cgaaaacccc
  1284241 tggggggcgg gtacgctcga atggctgccg aacgatgtct attcgacgcg aagcattcct
  1284301 cacataacca gccgtgaacc cctctgggac aggccgagcc tcccccagga agtacgcgac
  1284361 ggtcaccatt atcttccgaa cgctccaacc ggctggcgag agaccatcgt gacgtcgccg
  1284421 atccatgccc gcccgcaata tgtcatccag atgcccggtc ccggatggcc gccttttctc
  1284481 gcggccgtct ttacggccgc gtttttcctg ctgctgaccg tcaagatggt cgcgattgca
  1284541 gtcatctgcg gggtgcttgc catcgtcttc gtcctcgcat gggcctgggg actggacccc
  1284601 ggcccctcga aagggatgat cgaaatagcg aaaggcgtcc ggctgcccac ctatatgagc
  1284661 ggcccgacgt cgcattcctg gtgggccatg gtggtcctga tgttcgtggc cgggtccctc
  1284721 tatctcgctt acgtcttttc ctacctgttc ctgtgggtcg tgtcgccgga ggtctgggcg
  1284781 ccagccggat ctccggcgcc gccgccgatc ggctggcccg ccggttcggc ggcgctgctt
  1284841 ctcgcaggct ccggcatctt gtggctcgtg agccgaaaac tccagcagta tgcggcgtcg
  1284901 cgcctggcca tgtcggcggc cctgcttctt tccctcgtct gcctgacggc tgcgttcatg
  1284961 ctggaaacct gcggtcacct gacgaccggc ctcaaccctg gcgagaacgc ctatggagcc
  1285021 atggtgtatc ttggggccgt gctgtttgcg cagcttgtct tggccctgtt gatcatgggc
  1285081 ttgttcacct tggcacggca tctcgccggc aaactggacg ccgtgcgccg cgtgacctac
  1285141 gacaattacg cgctgctgta ctactatacc gtcgcccagt ccttgctggg ccttgggctt
  1285201 attcacggtt tcccgcgatt gatcggatag gcgccatgaa cgaaccgatc cacgaaccac
  1285261 ccgtcgccgg tgcgattctc tttcttctgg ccgggccgat tctttggggt ggacatctgc
  1285321 ttgccgtcta caccttccac gccgtgacgt gcgccgtcgg gggaccgtgg gcgacggccg
  1285381 tcgttccggg atccatcgtt gcggccacac tcgccgcggc cggagccctg ttgttgggct
  1285441 tctcgtttcc gggaaagctc gcacaggcgc ttcgctgttt cgatcaggac gacagccaac
  1285501 ccttcctgat ccgcgcggga cgtcttctga ccgtcctatc ccttgcgggt gtcctgtgga
  1285561 ccggctcggg ggcactcacg cttgcgccat gcgtgcagtt caggtgaagt ctaagccgaa
  1285621 ccgcgcaaca tgatctcggc gctcagcaaa atgcgctcgt cgtccctaaa ggcttccccg
  1285681 ttatgcgaag tctcgcccag cttgaacagg agcaattcga tcgccagcct gccgatctcg
  1285741 ttgtagttct gcgcgactgt cgtcaggggc ggacaagtgt agcgggacaa gggatggtcg
  1285801 tcatggcccg cgaccctcag atcgctttcg gcatcacgtc cgaccttgag gccggattga
  1285861 aacgcggcgg caatgacgcc gaaggccact cggtcgttgg cgcaaagaac ggttcgcgtc
  1285921 ggaaatccgc cttgcgacag gatgcgcagc gtctcgtcga aaccgaattt ctcgaagtcc
  1285981 caggaggcgt ttgcagcggt ttcgaccacc gccggtttca tcttcagttg ccgcatggct
  1286041 tcgacatagg cctcttgccg caccaaggcg ttgttgttca ccgggggcat gccgaaatag
  1286101 cagggcgggt cgccagaacg gcagaggtag tcgaccatta gcctgaaact ctgccggttg
  1286161 tcggttccga cgaaaggtga actgtcgtcg agcggcgagt cgacatagat gagcgggata
  1286221 ctttgcccga gcgcgctcag cgtctggtga tgcgactgta cgccgagtgg tgcaatgatc
  1286281 gccccggcaa cgttcatcga cttgaaggtt tcgattgccc gttcttccag ttcgggcctg
  1286341 ccgtcggagg agaggacgaa ggccaggaag cccgactgat ccgcaatgtg ctcgatgcgg
  1286401 cgcgtcagcg ccatataaaa cgggtccgtc gagttgggca cgatgatccc gagaatattg
  1286461 gtgcggcggc gatttaggtt gacggcgaag atattgggcc gaaagcccga ttgcttgatc
  1286521 gccgcctcga tcgcgtcgcg cgtcttcttc cgaaccgacg agggatcgtt gaagtatttg
  1286581 gagacggtag ggcgcgacag gccgacgaac tccgaaaaat cctccatcgt cttgatctgt
  1286641 ctcgtcacgt tcgaagcgcc cccgcttata tgttttcgtg ttccggaata ttcacggaat
  1286701 acgccgcctc cgctagagcc ggatgaggaa aagtgcgtgc ggtttccgtt cgcttcccgc
  1286761 gtctcaactc tttggaatcg atcaccttca tgattttagt cgatcccaaa agcattgata
  1286821 tctagagccg gcacgccgcg aaatagtcct gcagaacagc gtctattgcc gcaagtgcca
  1286881 gaggtttggc ctgcggcgcc acctcgccgt cgcgaacgcg ggcgtaactg ccggcgagaa
  1286941 actggctgat cagcgtttcc gggatcgtca cgccatcgag caacgccatg agttcgtcca
  1287001 ccgcttcagc cattttttga tgcggccagt aatagcggat ccggtcgcta taggagaaat
  1287061 ggcgctggat gcgctgctca tccgccgaac cgtggtaata tttgccccag tagaccggtt
  1287121 cctcgcgcat cacggcttcg gtgacctcgg caagcgaccg ctcgcgcttg ccgggaaaga
  1287181 ggaaagcggc aatctgatcc aggccgtata gcgcctcgcg aagtgcaaag gtgaggccgg
  1287241 ggccgacctt caggatcgcg aacccgtcgg caaccagctc gcgaagcgcc tcccgcgtct
  1287301 ggtaatcggt ggaatgagct tcgaagacca tcccttcgag ccggcgcagg ctggcgctca
  1287361 gctttgcggc ctttgaccgg tcataggcaa tgacgttccc gttgccgaat tcgacgcccg
  1287421 gctggaccac ggcgccgacg acgcggctga aagcaccggc cgcgcctgct tccttgaacg
  1287481 cttcgcgatg gacccgcacg gtctcgatcg ccgcttccgg agcagtcact tcgagaacat
  1287541 cgagctcttc gagcgcgccg cccggtatcg ggacttccgt gccgatgatg tagaccggga
  1287601 gaattccccc gcgatcgcga atggcatttt ccgcgactgc tgccagccgc gcggcccggg
  1287661 ctgctgtcgt tgcatcgggc agggcgatcg gttctccggc gcatcccatg ctggtgtcca
  1287721 gatgcagctt ggtaaagccg gctttcgcat aagcctcgat cattgtctct gccttggcca
  1287781 tagccttttc ggcgggcagg tgcttccagg gattcggccc cagatgatcg ccgccgagca
  1287841 ggatccgatc ccgggggaaa tccagcctgt cggcgattgc gcctacgaag cgggtgaaat
  1287901 ccgccggcgt cattccggta tagccgccgt cctggttgac ctggttgcag gtcgcctcga
  1287961 tcagcaccgg ggtaccctcc cggcgtgcgc tcagcatggc ggcctcgatg acgagcggat
  1288021 gcgcggaaca gatcgacggt atgccgcggg cccccggacg ctcgctccaa cgggcgatgt
  1288081 cgatcaggta attctcttgc atgatcaggc cttttgctcg gtgagaaata tttcgagttc
  1288141 tgtccgcgtc gaagcgcctt ccatcgggcc gaagtgcatc accgcgcggg caccggaagc
  1288201 ggtggcaaat tcaagtgctt cgcgtggaga cgcgccgttc agccagaagg tgacgaaggt
  1288261 cgcaccgaag caatcgccgg ccccggtcgg atcgatttcc tcgaccgaaa agcttggtag
  1288321 ggtgagcgat gtactggcgt cgaaatagct cgcaccttct gccccacgtt tgacgacgac
  1288381 cgccttgacg cctgtggcga gcagctccgc aaccgcctcg ctttccgtcc ttgcttcggt
  1288441 aaagaggaaa agctcctctc cgctcggcag gaaaacgtcc gtcttggcga gcaccgtgag
  1288501 aagcgcctcg cgcattccgg ggctttcgag aatttccggg cgaagattgg gatcgaagga
  1288561 gacggtgccc gcgcctgcct tgacgatcct gatcgcctcg agaatgctat cgaccacgct
  1288621 cggcgcgtag agcgacgagc ccatgacgtg aatgtggccg cattcgctga cgagtcgggt
  1288681 cgcgcggcta tcgagcgtga tcttgccgca ggcgctgtcg cggatattga agacgaaagc
  1288741 gcggctgccg tcgggccggt agcggacgaa ggcgctgccg gtcgtggcga gcggatcgac
  1288801 ttcgattccg gaaatgtcga cgccgtcgcc cttcaggcgt tcgaggttga ccgtgccgaa
  1288861 atcatcccct ccgacgcgcg agatgatcgc gcatggctgg ccgagctttc cggcctggtc
  1288921 gatgaagatc gccggtgcgc cggaagggaa gggaccgatg aggggcgtcg cctgccggaa
  1288981 gccgtcgcct ctctcggtcg cgacgatctc gacgagaatc tcgccgatgg tcagtatctt
  1289041 gtgcattccg atgtcactca tctcgggttt cagcgctttg cctgcttggc gcgtacgtcg
  1289101 agccagacgg cgataaggat caccaggccc ttgacgatga gttggtagaa atagggaacg
  1289161 gagagcatgt tcatgccgtt gttcatcacg ccgatgatga gtgcgccgat gagcgtgccg
  1289221 accatggttc cgacgccgcc tgcaaggctg gttccgccga gcacggctgc ggcgatggca
  1289281 tcgagttcgt agctcatgcc ggcattggtc tgcgccgaga agaggcggga ggaaagcaga
  1289341 atgccgctga tcgctgccat cacgccggag atcatgaaga tcaggatctt cagccggtcg
  1289401 accttgatac cggagtaaac cgccgcctcg cggttgccgc ccgtcagata ggcgcgccgg
  1289461 ccgaagctcg tcttgctgag cgcgatctga ttgacgacga agagcacggc gacgacccaa
  1289521 atgatgatcg gcaggccaag gaagctctcg gtgccgattg ccgtccaggt ttcgttctcg
  1289581 atcattgccg gggcgccgtt ggtcggcagg ctgaccatgc cgcgatagat gcccatcgtc
  1289641 gcaaccgtca cgatgaagga cggcaagagc aacttggccg ttagtacgcc attcagcatg
  1289701 cccatcaggg cgcccgcaag gagcgtcagg gcgatcgccg gcacaaagcc cattccgaag
  1289761 gcaaagcact gcgcgccgac cattcctgcc accgctatga tcgagccgac ggaaagatcg
  1289821 atttcgccga gcaggatcac ccatgtcatc ccgaaggctg cgatcgcaat gacggcaacc
  1289881 tgctgcagga tgttcatgaa attgatcaag gtcatgaagc gcgggttgaa gaaggaaaag
  1289941 acgatgcaga gcatcaccag ggataggaag atgccgccat attgcttcag ggcccgaacc
  1290001 agggcggctt tggtttctgt gttctgtgtc atgattgaaa acctgtcgcg tgagccatga
  1290061 tcgtctctgg agtgaggtcg gggccttcga gcgtcgctcc cggcgcgccc tcatgcatga
  1290121 cgacaacgcg gtcgctcatt cccagaactt cgggcagatc ggaggagatc aacagaattg
  1290181 ccgttccctc cgctgccagc tgacggatta tcttgtagat ttcgaacttg gctccgacgt
  1290241 cgacgccgcg ggtcggctca tcgaggatca gcactctggg ccgcgtgaga agccatttgg
  1290301 caatcacgat cttctgctga ttgccgccgc tgagcgcacc ggatggcgtg tcgagcgagt
  1290361 tcgtcttgat cgagagattg ccgacctgtg cggatgccgc ggctcgttcc gcgccgttgc
  1290421 ggatgaaacc gaaaccaccg gtgaagtccc cgagtgcagc catggatatg ttccactcga
  1290481 cgctgtggcc gaggacgaga ccttcttcct ttcggttctc tgtcacgaag ccgacgcgcc
  1290541 gggcgatggc ttcgtccggc gagcggaacc gcacgacctc gccgttgaga cgcacagcgc
  1290601 cgctggcgtt tttcatgccg aagatcgcgt tcatcacttc cgagcggccc gatccgacaa
  1290661 ggccgaagaa gcccaggatc tcgccagcgc gtacctcgaa ggagacgtcc tgaaactcgc
  1290721 cttcgcgtgt caagcgctcg actgaaagga caggggcctt atcccttgcg accgcatgaa
  1290781 ccgccggcgg gtagatctcg tccatgcgtc gcccgaccat cagggcgatc agtgcctcga
  1290841 tggtcacctc ttcgcgcgca tgcgtggaaa catactcgcc gtcgcgtatg accgtgatgt
  1290901 cgtcgctgag ccgcatgatc tcttccatgc ggtgcgagat gtatatgatc gcaacgccac
  1290961 gctctttcag ccgggcgatg atcgcgaaca ggatctccgc ctcgctgtca ctgagggagg
  1291021 aggtcggttc atccagaatg acgacctccg cgtcgtggct caggcccttg gcgatctcga
  1291081 cgagctgccg ttgggcgatc gagagattgc cgaccttctc ggtgacgtcg atcgggagtc
  1291141 caaggtcggc cacgatccgg cgcgcctgtg cgacgagcgc cttgtcgttg atgaatccga
  1291201 aacgacgtgg ctcgcgcgtg gcgaggatat tctccgccac cgtgagattg ttgcagaggc
  1291261 tcaattcctg gaagacgatg gcaagtccga gcgaggccgc atcctgcggg ctcgcggggc
  1291321 ggtaagcctg cccgtcgagg gtgatttctc ccgaggttgc cgtgtgcacg ccggcgagaa
  1291381 tcttcatcaa tgtcgatttg ccggcaccat tctcaccgag cagtgtgtgc acccggccgc
  1291441 gccgtacttc gagccgcatc cccttgaggg cagcgacctg cccgaaggac ttggtaacgt
  1291501 cggtgatctt gaggatggtg tccgcggcgg aaccatgcat ggctgtgcct ccttaaaccc
  1291561 gaccggagcg tatccggccc aacggccgga tacgcttgcg gtgtgctgcc gctcgaagag
  1291621 ggcagccgtc ctgggaggga cctatttcgc ggtgtagacg ccgggtacga ttggctgctc
  1291681 ggccggaacc gtctcgccgg ccacgacctt tactgcggtg tcgatcgcct gcttgcccat
  1291741 ctgatccggg aactgctgga taacgccgac catcaccggg ttcgagtcga cggcgtcgcg
  1291801 cgcttccttc attccgtcga aaccgatgac cttgacctgc gactccagtc ctgcggcttt
  1291861 cacggcaacg gccgcggcaa gagccgcatc atcgccaaag ccgaaaatgc ctgaaatatc
  1291921 gggattggcc tgaagcatgt tctgtgcggc ggcgagggct tcggcgcggg tgatgcccgt
  1291981 ttggaccgcg acgatctcca tttccggatg cttggcgatc gcttccttga aaccgttgac
  1292041 gcgattgacg accgactgaa ccgtcggata gtcgacgatg gcgactttgc ccttgcttcc
  1292101 aagaaccttg gccatcagtt cgccggcttt tacgccgcca gtgaaattgt ccgttccgat
  1292161 atgcgaagtc acggtcgcgc cattggccgg aacatcgacg gtgatcacct tgattccggc
  1292221 cttctcggcc ttggcgatcg ctgcgcgtac gccctggctg tcgacgggcg aaatgacgat
  1292281 cacatccacg cctttgacga tgaagtcctc tacgtcggca agctgcttgt tgaggtcctg
  1292341 attggcgatc gcgacttcca gggcgacgtt cttctccttg gcttcggctt tcatcgcctc
  1292401 ggcaagttcg atgtagaacg ggtgctgctg ggtcaggagg gatgcgccta taccgtctgc
  1292461 gaaggcaccg gatgccagga gcgtgagcgc ggtgccggcg acgatcgtct ggagaaagcg
  1292521 ggtcatattc atggtttcct cccttggaaa cggcgggcct tacgttctca accaaggcag
  1292581 gcaggcccgt ccgtccctga cctcggcaag ggagtagaca ccataaaact ttccacgcgt
  1292641 caattttaaa acgtacgtat aacaataaaa acttcgtcgt gaggaaatat tgatgggctg
  1292701 aatgcgaggt gcctgctgga gtcctcagtc cgattcctcg gtgttccggt cctgagagta
  1292761 ttggggcacc aagaggggag gaagccagtt ctcgcgcctg acaacccaga tctcgtattg
  1292821 cggttcgagt cccgccggga cattatccag cgagccgaca cggatttcgg tctcgtcttt
  1292881 tcccgggttg aagagacgcg atccgcagac ggggcaaaag ccacggccgg cgaagatttt
  1292941 cacttcaccc gtgcttttga acgccgggct gggccagacc gcgaaagtca cgaaagagga
  1293001 gccgctttcc ttacggcagt ccgaacaatg gcaaagccct acccgcaggg gttctccgct
  1293061 gacttcatat ctcagcgcac cgcacaggca tccgccggtt ctcgtaacca tttccatctc
  1293121 ctgccttcga cttggggcgt gatcatggaa acaatccgcc tgacctccgc ccgcatctgg
  1293181 ctcaactctt tcctccgtcg catgtttcat aagtttaact tgggtggcca ggatttgtct
  1293241 gtgggaggcc atgcgaccct tggggagcgg gaggcacgac cctatgtaag agacggtgca
  1293301 acaacccgaa ggtgaacgcc gatgtcagaa aaaccgatca gaattccggg acccgaccat
  1293361 ccgatcaccg tagaacgcaa tccggcccgt gtcgtcgtca agctcggcga ccgcatcgtc
  1293421 gccgacacgc gccatgcgct gacattgcgt gaggcgtcct atccgcccgt gcaatatatt
  1293481 ccgcgccgtg acgtcgacat gtcgctgctc gcgcgaaccg atcatggcac ctattgcccc
  1293541 tataaggggg atgcatccta tttcagcctc acgcccgggg gcgagcgctc aaaaaacgcc
  1293601 gtctggacct atgaaaatcc ccatgaggcc gtccgcgaaa taaaggacca tctggcgttc
  1293661 tatccggacc gggtggattc gatcgaggaa gtatagggcc acttcttgaa atcggagagg
  1293721 gcgttgagta acgggaggcg cggtttctgg accgactagc cggcaaaaga caatcagact
  1293781 gcttcttgaa tatttcgagt tgtacaaccg ccatatctcc ggatgaccaa gagagaagcg
  1293841 gctatgtcag cctcccatta cttgaaatct tccttggtgt catcttcgta gacgacgcca
  1293901 caaaggcacg cggtaacatt tacgtcgtgt cggtctaatc tggccgctcg atcaagtttg
  1293961 atgccggcat gggacccgcc ggtagtatag gcggcgccaa ttgccacctt tttcgtcaaa
  1294021 atcttcaggg atctgtccaa ttcgctggcc cagagcgtca ctgaacatga cgcttgcgtc
  1294081 gaccattcgg gcaggccttg tcaaggaact tgcccatccc cgcccacgat atcgaagtag
  1294141 aagttatgga tgatgacggt aaacctgtaa ccaagactgt cgtcaaacct gagcaaatca
  1294201 atgaaggtgt gcgtatcgat ggtctagcgg acggtgcgac gttgagagaa ccggggaaat
  1294261 accggtgtgt cagacgatgg actagggtct acttactgca gaaattgtag tggcgctgca
  1294321 gtgcgtaatt tacaagaaca tgttgcaggg agaagagatt gatgccctga aatcggagaa
  1294381 gcgcgccctt gccgaacggc tcgcccatat tgaggctgac cttggccttg cctaaaattc
  1294441 atccgagcct agcatcctta atgcagagct gccggcgttt tagtggctgc agttggaggg
  1294501 attgggtctc tcgcccattc ggcgacagca atcgctgaac tgagcagtac ggctggcagc
  1294561 gccagcgcgg cgaggaagct gatcacgctc ttcctatgag atcgcctgcc gccccaatcg
  1294621 taagacattg tgcttgcttc ttcgtgatcc gaacaatggg ttcggctcaa gcatatgggc
  1294681 acgttatgcg atgctggtcg agtgaattta ggtgaagcat ggctagggaa actcttcccg
  1294741 tcgcctcgaa ctcatgttcg agcataaact gcgaagtgcc gcgcctttgg tgctgcattt
  1294801 aaaccgagag aagaggcctt cttgcgtcca agaacaaaag acccgtgatc cgggccgcga
  1294861 tcacgggtcc agccgcagcc atgtttacga ggcgtgactc gcggcttttc tacaactgct
  1294921 gctcggacct gcttcgggct ggatgtcata gcgggtgagg gcaacgcccc aatcaacaag
  1294981 gcaggatcac cgccgcttct tggcgcctcc tcgagggtta ttccgaaact tggcgagcga
  1295041 acgcctgagc ttcgcgatcc ggcgggtcac gtgcgcgata atgagaaagg gtctctcgtt
  1295101 ttccagattg atgacgctgc cgcatcttcg gcacgaaagt tcatcgtttg cctttaccca
  1295161 gtccaccgtc ttgctggcct cgtgaccgca ctcagggcag gggatgtcga tctcttcgct
  1295221 attaagcatg gcggcaccta ggttgagtgc gaaatgaacc acaaccaatt gcgcggcgca
  1295281 atgcttagtc ttttactgaa aacgggttaa gtgcggcccg ttcgaccgcc cctttcggcg
  1295341 ttcgaaatta cgctgagctt gcgccgggct aagagtcagg ttcgaccgct actgtgaccg
  1295401 gctcgatcgg ctttgccgcc aaatccttga ggtcttcggc gaggcctgcg agctgcgccg
  1295461 cgaagtcaag aagatttgaa gcggcgcact gtgccgcgac ttctgagagg tcacaagcta
  1295521 gttcgatgcc gccggcgctt tttgctttga gatcatccat gtccaagtcc ccatttccat
  1295581 tgatttggat caatggcgag gcccgtcaag gccgcgggcc ggtgacgagc ctctcggccg
  1295641 cctgcgaggg gcaaagcggc caatgtcagt ctaagcccgg acattgccgg ccgctacaaa
  1295701 ccagccgccg aatattcccc aatgacaacc aggagacatc aatgagcgct atcaccgttc
  1295761 agcatgtgcg cgctgctgca aagggcaaag tgaacgaaag caacctcgcg tccgtgcttg
  1295821 cgcgttgggt acggggatcg attcgggatg gaccggccgc accgtctcgc ccaggatttg
  1295881 cgcagctcat gcatgagagc ggcgatttcc gctacgaccg cgagatctgt ggcccaacgc
  1295941 cggcgcagca gtgctacgac acgcgcaccg atctcggcaa cacgcccgcg aaagatggcg
  1296001 acggccatct ctaccgcggc cgcgccggaa tgcagcttac cggcaaggac aactatcgcc
  1296061 agttccgcaa ctggtgctgc gccgccggcc tcgattgcct ggacttcgtc aaagacccgg
  1296121 acgcggtcaa caccggtcca tgggaaggcc tgatgcctat gttctattgg gccacccgca
  1296181 accttaaccg ctgggccgac gagggtgacg ccgagactat cacgaagaag atcaacggcg
  1296241 gcaagaacag tttggccgat cggcttgacc gtctcgcccg tatgtcgctc gtgctcttcg
  1296301 aatatcgcgc cgataacgtt ctgcaattcc aggctgacga acggctgcag gtcgacggcg
  1296361 atgttgggcc caagacacgc gctgccatgc ataaggcgct tgtggcactc accccgggcg
  1296421 aagcggcacg gccggaagtc aaggcggcgc cggggacgga ggagaagccg gtaacgatca
  1296481 caccgcgtgg cctcgatgct tgtggaagtc gaaagaggtg atcaccccat ctgcatcggc
  1296541 ggcggcgttt cgctgcttac ggcgatcggc ggaaatcccg tggccaaacc tcttattgat
  1296601 ccttgtcgcg ttcgtaggga tcaccggctt tctggcgcaa gaacgccgat cggaaggccg
  1296661 tggcaaaaca ggtcgagggg atggagtaat gttctccacg ccgcgcctca tcgcggctgc
  1296721 ggccgccctc gccatcgttg tcgccgtagt tgtttggatc taccggcagg gcggcgacga
  1296781 agtcagaacc tccatcgaaa ggcagaacaa taaagctggc cgcactgcgg acgatgtccg
  1296841 ctctcgcttt gacctttgtc ccgcaggaat gtggaatttc ggcgccggca agtgccgcct
  1296901 gtctccggcg agtggtggac gattggctga atcgccttga cccgccttac tttggagcag
  1296961 aggttcctgt gaacgatggc ggcagttacc atgtcaccgg ccgatcggag cgcggtcgat
  1297021 ggccactcga tcgagcgacg gggaactcgg ctcgcgtttt ccttgagcag tgccgatttg
  1297081 aatacaggag accctgcaga agtttaagcg ttatgcaagt gtggccctaa gcttcgatcg
  1297141 tagaaagaag gtgagatctg tgaaagcctc aacgctcgcc tttgcggtgc ttgccgcggc
  1297201 aattagtatg tcgccggcac gagcccagac atgtatagga atttgcaacg gcggtacggg
  1297261 aggcagcacc aaccacaacc tcttcatcga gagagagtac cgagacttcc tgcagcagcg
  1297321 atatccaaat tacggctccc gctatcgcgg catgagccct gacatcagca taggtccggg
  1297381 cgcaactgtt ggtggtcccc ggcccggagt gcgtcaaaag tttcgacttc gccagccaag
  1297441 ggcaatcgac gcgaaaaggc atcttcgctg gtgccaggag cgatacctat cgtatcgact
  1297501 ggctgacgac acgttccagc cgttcgaggg tgcgcgccgc ccgtgcaact caccttacaa
  1297561 ctgaaggggc gagaacggcc gctcaacgcg tgtccggaag cacttccatg gcgagcgtaa
  1297621 tggcacgcgt cgagggttct tgtggggaaa tgttcgaaaa cctgattgtg ctcgtcgtga
  1297681 ctacatcgcg acgctctccg gcgtcgcagc tccctgctca cgcgcgacca tcacgaggga
  1297741 cggtgtccgc tctcgctttg acctttgtcc tccagggatg cgggacgtcg gcgccggtaa
  1297801 gtgccgacgg cccccgccgg gtggtgggca ctgacttgat cggcgagcgc agcgcgacgt
  1297861 cagaggatca gaggaaaata gaccgaaccg tcgttggcat ctgtgccgcg gccgtctgga
  1297921 cgacagcgga atgcgcccgc cacggcgaag cgtagcagta aaccacccag cattgcatac
  1297981 gaggggcagg gcattgctga agcacaggaa gccgaaagat ggttgcaact ccgaaatgga
  1298041 gggttgaata taatctcaac accctggtga tcctgttcgg cttcgccggg ggcctcatag
  1298101 cgtggggcgc gacctgggag agggtgaacg ccaaccagga ttcgcaggct aattccatcg
  1298161 atcgcatcga caagcgctga ccgcggcaga agtctccctc cggcagatcg acaatcacga
  1298221 gcttcgaatt tcggcagtgg agaagctggc gtaagcgaca aggagacccc gtctagcagc
  1298281 atcggggtcg ggtacggtat ggcggagaga cgatttcacc gagtgtgagc atctatgtct
  1298341 gcgcctatag ctagccctag aacgatccat atgattgaag ctgtgccgga acgccttgag
  1298401 ggttcacctc gtcagttgcg gcgtttttgg tcggacgagt tcaaggcctt tgcggtcgag
  1298461 gaggcgtcca ggccgggagc gaacatttcg gcggttgctc gacagatcgg tattctgcct
  1298521 tcgcagctct ttcgatggcg acgggagctt agtggagatg gtgagcaaag ctctgctctg
  1298581 gcgaaagaac aacagccgag atctgcggca attagggaac gcgttgtgga ggtcgtcatt
  1298641 ggcgatgccg tcgtacgtgc cggtgcggac gtcgaggagg cgcacttgca gcgggtgatc
  1298701 cgagcggtgc ggtcggcatg atcccctccg gcgtgaaggt gttcctcgcc agtcatcctg
  1298761 tcgacttccg caagggtccc gacagcttgc tgtcgctggt gcgggatgcc ggcaatgatc
  1298821 cgttcaacgg cgcgctatac gtcttccggg ccaaacgagc ggatcgagtg aagatcgtct
  1298881 ggtgggacgg ctccggcgtc tgcctttatg caaagcggct ggaaaaagcg cagttctgct
  1298941 ggccccgcat cggccataac cgggttcagc tcaaccatgc ccagcttctg gcgctgatcg
  1299001 atggcatgga ctggaagcgg gttcgatccg tgccggtcaa gccgccggag attgttgggt
  1299061 aaaagccctg cggcgaagtg aatcagcagc ctgaaagggc aggaaaaccg gggcaaaatg
  1299121 tgcttttgtc gacccgatga cgccgcccga tctcaaactc ccagatgatg ttgaagcgct
  1299181 gaaagccatg gtgcttgcca tggccgagaa ggcggcgcgg gcggacgcgc tgcagaacga
  1299241 ggtcgccgat ctcaaggcgc gcaacgccga tgccgatgag cgcatcgagc ggctgacgca
  1299301 gatcctgaaa gcattcgatc gcgcccgctt cggccggcga tcggaaaagc tcggctcccc
  1299361 aaccaccgac gacgagcagc aggcctttgt cttcgaggaa attgaaaccg gcatcgccgc
  1299421 gatccgggca caggtcaaca agggccgcga gcgtccggaa ggcaaacgtc cgccgcggcc
  1299481 acgcaagggc ttcgcaccgc atctggagag gattgaagtg gtcatcgagc cggaggagct
  1299541 gccggagcat gccggcaagc aaaaggtgct gatcggcgag gacgtgtcgg agcggcttga
  1299601 tgtgatgccg gcgaagttcc gcgtcatcgt cacccgccgc ccaaagtatg ccttcaaaaa
  1299661 cgaggacggc gtcatccagg cggcggcgcc ggcacacatc atcgaggccg gcattccgac
  1299721 ggaagcactt ctggcgcaga tcgccgtctc caaatatgcc gatggcctgc cgctctaccg
  1299781 gcaggaggcg atctacgccc gcgacaaggt cgaactcgac cgcaagctga tggcgcaatg
  1299841 gatgggcaag ctcgggttcg agttggagat cctcgccgac tacctctttg atgagatcaa
  1299901 gaagggggag cggatcttcg ccgacgaaac caccttgccg acgctcgctc ccggctccgg
  1299961 atcgacgaag acagcctatc tatgggccta tgccagggat gaccgaccat ttggcggcag
  1300021 cggtccgccg atggtcgtct accgctttga ggacagtcgg gccggcgagt gcgtcgcccg
  1300081 gcatctcaag ggctaccgcg ggatcctgca agtcgacggc tatgccgcct acaacaaact
  1300141 ggtccgctcc gatcgtggca atgacggcgt cacattggct ggctgctggt cacacagccg
  1300201 gcgaaagttc tatgagctgc atgtcgcgga aagctcaaag gtcgcaacgg agacggtcga
  1300261 gcggatggcg aagctctggc agatcgagga gaccatccgc ggcaaaagcc ctgaggcccg
  1300321 tgtcgcggcg cgtcagcaca cctctgtggc tgttgtcgcc gagctcttcg ctctctggca
  1300381 gaagaccctg ccgcggatct caggcaaatc gaagctggcc gaggcgctcc gctacgcgat
  1300441 ctcgcgtcgt gccatcttcg aacgctttct gaccgacggc cgcatcgagc tcgactccaa
  1300501 catcgtcgag cgagcaatcc ggccccaggc gattacgaga aagaactcac tcttcgctgg
  1300561 cagcgacggc gggggacgga cctgggcaac catcgcgacg ctgctgcaga cggcaaagat
  1300621 gaataacctc gatccgcttg cctggctcac tcagaccctc gagcgcattg ccaatggctg
  1300681 gccgagcagc gaaatcgacg cactcatgcc gtggaattac gccgcctgaa cggcctcggc
  1300741 ttgtcgctta caagctggcg accgaggcgg ccacttatca atgaaagccg tcgagaatac
  1300801 gctcaacagc ctttccatcg atacacgtgt gatgcgcgag atccttcaaa ggattgaagc
  1300861 cagtcagcga gacggtgctc agctgcgccg tgacgacaga gttgctcgcc aggcattgtt
  1300921 gaattcgaca agttgcgcga cgtacttcag cctgctttca tcctctcatg gacactaaac
  1300981 ttgcagactt aacactgaag ccttggctca tcgacgagcc caaccaactc ggatatgagg
  1301041 tggtcggaga tatgcagcac cttcccacag aagagatgct gcggataccg ggatgggtgg
  1301101 gcacttctat cggaaaattg cgaaggcctt ggggcgagag ccgttccctg actttaataa
  1301161 gcgagtacgg cgctgacaag cgaacggctt tcccttgatt ccactgtcgc tgggagtaca
  1301221 atgtgtgaat gcgatgttcg aagcggttcc cttgaatgga acagggcgat tgcgccccac
  1301281 ttattcgatg accacgtcgc gaccggagct gcagcggtcc cccactgcag ctcttctgtg
  1301341 tcaggccatc tggctgtcct gaggggcgga actggcgccg ctatcgtggc catcgccatc
  1301401 gtccggccac gtagcacgac ggttcacctt tcatccgttg tgcgcgggcc gtgcacggca
  1301461 actgaaatct ccccttccaa atgccagccc tgcgtgatcg accgcccttt cgcgcttcgg
  1301521 cataggcgcc tttgctgaat ctttcccagt ccaccgcgtt gccgctctcg actaaccagc
  1301581 gattgacgtc gcggccatca gcgcgaaagc aaacgctcac gatccgtttg aaacgatccc
  1301641 tttcgccaaa cccgcagcgc gttgggtgcg attcggcgag gaacgtgtcg agttcaagga
  1301701 cgtcttgccg gccgcaccga taggcgacgc cgtggcatcg ccgcatttct gccagctttc
  1301761 cggagcgtcg accccgttta ggcggatgcg ctcaccgctg atctccagcg tgtcgccatc
  1301821 ggcgtccgat tacagggacg gtagcgcgag ctagaagggc aagcaccagg gtgattacga
  1301881 atagcagtag agctgagagt ttcatttgcc gggtgctgac ttagtggcag tgcactttgc
  1301941 cagtgctttt ctgcatttgg cagcactgac caggtggtga acttttaccg ttccagacag
  1302001 atcggcggtc ttgcgagcgg tctcggcatc aaggcctcga aaggcaaaac cgggcatcta
  1302061 tcgtcaacgc tcccgaaagc ggaacggatt ggcccgctag cgctgaaacc ttggctacgt
  1302121 cgagcccatt gcttgcgacg cggccgcgga acaccggagt gtcggccgta acgtcggcag
  1302181 cgatatttgc ggcaacgctc ccggcgtcga gccccagatg cccgagctca gccatcagct
  1302241 ttccgtcttt aagtgcggcc gaaaaggaaa catccgatgc ggaaatatcg ggccttagcg
  1302301 ctgatgctta agtcggcatc gaagccggac aggaattgta gattagcctg tttcgccgta
  1302361 tccgctattg gggcaggcgc ctgcgatggt tccggcgtgg cgttcatcaa cggcgtcaag
  1302421 tcgagccgct ccgcctcaat atcggcaaga acgcgcgcac gctccccggg cacgaagagc
  1302481 gcgtttatgc tgaaggcctg ttcgtcgagc tccacttcgc cgtcgcgaac cagatagcta
  1302541 ccattcgcat tcagggtgac ctcgccggct gcttccagct tagaaagccc cggtgcgaaa
  1302601 gtggggcccg ctgccaagat cagggcgagg tctgccggtt ggcgctccag cagcgggcgc
  1302661 aaggacgaga tggtaaacgt cgcctggtag ttccgctcgt ccatgcgggc ggaagcggaa
  1302721 agcgaaagct cttcgtcgat atcgggagcc gagagcgtca gctcgacatc agatacgact
  1302781 tcttcggcgt tctccgggct tcgcctgata aaagtgccag atgggattga gaccgcctca
  1302841 atcgccttcg ctcgaggaaa tcaacgaggg cgggaagcgg gtcgccgtgg cctgaccgtc
  1302901 gccgctatgc gccgacgccg tctcctccgc cgccttttcg gtaagcatga tgaccggatg
  1302961 gttcagtttg atctctttga tgcgcagccg ttccgaccag agggaggaca cagcaacgga
  1303021 tccggcgacc tctacgaact cggccgtaac gccttccgtc tccgccgaga gtgtcacatc
  1303081 ttccgctacg accgcgaggt acggaaagac ggagagcttc acggggccgt tgagcgcaat
  1303141 cgaactgccg gtcgcagacg acaattgcct gccgagctcg gcacgcatcc agtcgcagga
  1303201 aatcaggctc ggcagaataa caattgctgt gaccgcgagc gcgtcagcac ccagaagaca
  1303261 aagaataaag cgccgcatcg cattctactg ggtgtgaaag gtgttgattc gctatcgatt
  1303321 tccagaaagc gcgatttcgc aatcgtcttt tgacgtgaga acctcaacgt aacgtcagcg
  1303381 gcgaccttgc cgaccgcccg gttctccaat cgcggcgcac cggctcgcga cctgctgacg
  1303441 atcagcaggt tcgcctgcat tggccaaaag gactagctcc tcgagcggat gagtacagct
  1303501 catccaccat tggcggtcta ccgtatccgt gaaggtcagc cgagaatggc accgtgagtt
  1303561 tcgctctcgg ttttgggttg catgatgatg aatggtgcgg atgcacgctt ttatttttca
  1303621 atccttctga ggagattgcc gtatctggtg gcgatcgtcg gttccgtgat tgcgcttacc
  1303681 gtcattgtcg ctagcatttt accgccccgt tatcgtgcga gcgccaaaat tctcgtagag
  1303741 gctccgcaaa ttcctgtgga actggcgcga tcgactgtcc caatacaggc ggcccagcaa
  1303801 ttgcagatta ttcggcagca gatcacgacg cgcgacgacc ttctcgcgct tgccgacatg
  1303861 ctcgacattt acggcaaaga agaagacgaa ctgtccaagg atgacatcgt agataatatg
  1303921 cgctcccgca tcacattcga ggaactcgcg ttgagcgcgc catacggtga tactggtgcc
  1303981 tctgtggcaa gcgtgagctt caccgcggca gatcctgatc ttgcggccag ggtcgctaac
  1304041 gagcttgtcg actttattct gctgaagcag cagcaacaac gcaccagtcg tgccgcggac
  1304101 acggtcaagt tctttgatca agcggtcgcg agacttggca cggatctgag tagggccgaa
  1304161 ctcgaaattc taagatacaa gaacgaacat gcagacactc ttcccgaaag tcttgatttt
  1304221 cgccgcagtc aacaaacagg ccagcaacag agatggatca cgctcgagcg cgaagagtcg
  1304281 gatctccggg ctaagcggag cacccttgtc gagagttacg tccttggtgg ccaagctccc
  1304341 gatggtaagg cggcgacacc ggaacagctg gccctgcaag agctgacgcg tgcgcttgcc
  1304401 gagcagcgtg cgattttctc ggagaacagc cccaatataa tggcccttcg cggccgcatt
  1304461 gcttcattgc aggccacatt gcgcacgacg cagacaagcg aagctagttc ggcccaggac
  1304521 agggtcgcgc gttccccgct ggaccaacag ttggcgtata tcgacgagcg cttgcgcgcg
  1304581 attgtcgggg agaaggccgc aatcaccgat cgcatagacg aactgagcaa atcaatcagt
  1304641 gcgacgccgg aaagtgaaac cgttctttat tcgttcgagc gcgaccgggc aaatcttcaa
  1304701 tcacaataca atactgcgat agcccgacgc gccgaggcga tcatcggcca gcagatcgag
  1304761 aggcggtccg acgggagtag tttctcagtg cttgagcgcg cgaccgcacc tgagatggcg
  1304821 gagagcccaa atcgccgccg tatcgtgctc cttggcgcgc tggccggaac ggctctctcc
  1304881 gtggccttca tcgggctgct tgagtttttc aacgcggcca tacgcagacc caatgaactt
  1304941 gcgcggctgc tcgaccgtca gccgcttgcc actataccgt atatttcgac tgtagccgag
  1305001 gtacgtagtc ggatcagacg aacggtcgcc gcggtacttg ctgctgcggc tgctcccgcg
  1305061 gcattgatcg tagtccacca gttctatatg ccgctgccga tagcatttca gaatctctat
  1305121 cggtggctca ccacgctggc ctagcgcaga aagagcggag tgtccgcgcc gtttgtgcaa
  1305181 cttcggggag caggacatgg agcatgcgga aacgaccttg cacgagtttc ccgaagcgga
  1305241 acggctgagc cgaatcggag cggaaccggt ttggaagatg ctttcgccat gtcgagccga
  1305301 tccgcgttcc gttgcgggca gctggtttgt cacgacgggc cgatcaaatc cgaaacacgc
  1305361 cgcgttcgac atgctgcgta ccaagctgct gctagcgttg cagcaaaaga actggaagac
  1305421 ggttgctatc acgtcgccga ctcccggatg tggaaagacc tttgttgcat tgaacttggc
  1305481 gttcagcctg gccaaccaga aggattgccg cacggtgctg gtcgacctcg acctgaagcg
  1305541 gccgcagatt gccaagacgc tcggcatcga ggccccgtcg accatagaaa agtatctgaa
  1305601 aggcgagagt gaaatcggtg atgtgttcca gcgttacagc gacaatctgg cgattggcgc
  1305661 cagcaagcag gccgtgccgt tttcggcgga gttgctgcaa acccgcggag cggtaaagca
  1305721 gctgcaagag atgcagcaga agatgaaccc ggacgtcgtc ctctttgaca tgccgccgat
  1305781 gctgtccaac gacgatgtgg tgggatttct gccaaacgtc gattgcgtca tactcatcgc
  1305841 cgcttcggag caaagcacct tggctgaagt cgacatttgc gaacaggagc tgtcggaaag
  1305901 gaccaacgta cttggtgtgg ttttgaacaa atgccgattt gcacctgaga aatacggcta
  1305961 ctgaaggttg ggggagaatg atggtcgcaa ttttgaaagc ggttccacat gacgaagcga
  1306021 agaaagcgga ccggactgcc ccccggccgc tctcagcggt aattgtcacc tataacagct
  1306081 cagctgtgct ttctgagttg ctggactcgt taccagcggg cctcgctggg gttgatgact
  1306141 acgaagtgat cgtcgtcgac aatgcttcgg aggaccggag cgtcgacata gctctggacc
  1306201 atcccatcgg tgtccgcgtg atcaaaatgg cccgcaacgc gggctattcc gccgggatca
  1306261 acgcagcggc cgaagcgatc gagcccaatc ggaacctgct ggttctcaat ccagacattc
  1306321 ggctctaccc gggtgccgca cgaatattga acgatcttct ttccgataca tcggtcggga
  1306381 ttgtggttcc gcagatcctg gatgaggacg ggagcatcag tcgctcgata cggcgcgagc
  1306441 cgtcgctcaa gacagtttgg gcagatgcgc tcgtcggatc cgatattgcc gggaggttcg
  1306501 gcctcagcga gacggtattc gatcgagcac tttaccggga tggcggtcag atcgagtggg
  1306561 ccgtcggcgc aattctggcc attgccgccc ggacccgggc gatcatcggg ggctgggacg
  1306621 aagcgttctt cctctacagc gaggaggttg actatcagga tagggtgcgc cgcgccggtc
  1306681 tgtcgatcat ctaccaaagc gaagcgcgag tagttcatat cggcggcgac ttccagagca
  1306741 atccggcgtt gtgttatctg atgtccgcca atcgtgtccg ctactacaac ggccgtcacg
  1306801 gcgcgttgcc cgcaacgatg ttccgtctcg gtgtaatcgc aggcgagatc ctgaggctcc
  1306861 cgcttggaca gagacaccgc gcggcgttac gcggtgcaat cagcgctgca gcgcgacaac
  1306921 caagatgata cgtgatctca gccagattgt cgcgctacac gtatccatcc ggtcagggcc
  1306981 gcgatagcag aatggctccg gcgcttagtc gtatcgacgc gtgccggagg taacgccgac
  1307041 atctcaattg aattcaatag atggaacaat gttcgttgat gacttcgtag ccgggcccga
  1307101 gttcccgtct gatgtcctca acaagctggt caactgcttc ggcaaatctg acatctgccg
  1307161 ctttggacca agggctagat cccggaggat tgttccaatc cagtgccgta tcatgccaca
  1307221 ctgccatgcc atgcaatcgc tgtcggattt cattcggcaa agaacgcttg tcttcaatag
  1307281 gacctacgtc aaagcgttga tgagcagcgt cattggcgca gcgcgtcggc ctcggtgcag
  1307341 tcggcgatct gcttgccagt cagacggagg ctgacggggc gaccttcggc atcgacgagc
  1307401 gcgtggattt tgctcgtgag cccgccacgg gaacgtccca tgccgccatc gtctccatcc
  1307461 ccctctttcc cgtgaccgca tgctggtgaa cgcggacaca ggttcagtcg atcatgacga
  1307521 tgtcgccatc gtaagttcga aagcctcgga aacggcttca agaagacgat cccagacacc
  1307581 gcccttccgc cagcggacga agcggttgta gcaggtggtc ggcgcaccat agcgctccgg
  1307641 atttccgccc aaggcgttcc cgtccgaaac cgccagagga tgccattcag cacccgccga
  1307701 tcatcgacgc ggggaacacc acgcagtttg ttggacaacg gcggcgaaag gattgatcat
  1307761 tcgtggtcag taagttcgta gcggcggcgc gtcattcaag gctctctcat tcgaaagcct
  1307821 tgaatcatcg gcgcgactaa acaacaagtg attttatgag tttacgacct agtcacctgg
  1307881 aactaaaatt cactacattg tatgcttggc ctcttcattg gaggttgagg catggcaaat
  1307941 gcgactggcc gaccaacgcc cccattggtt ttgagcgagg cggagcggga atatctggag
  1308001 cgacaggtgc gcaagcatcg tgttgcacgc tccctgtcgg agcggtgccg gatcattctt
  1308061 cgctgtggcg agggagttcc gagcaaggtc gttgcggacg agctcggcgt gcatgaacat
  1308121 acggttggca aatggcgacg gcgcttcctc aaagaccgac tcgatgggct gctcgacgaa
  1308181 gttcgccctg gtcggccccg aaccatcgac gacgatcaga tcgcggctgt gatcgagcgc
  1308241 acgctgcgtt caacgccaag cgatgcgacc cattggtcga tccgctcgat ggcaggggcc
  1308301 acaggctttt cgcacacgac catccgccgg atatggaacg ctttcggcct gcagccgcat
  1308361 cgcacagaga cgttcaagct ttccagcgat cctttgttcg tcgataaggt ccgcgacatc
  1308421 gtcggtcttt atctgtcacc tcccaatcgg gcgctggttc tcagcgtgga cgagaagagc
  1308481 caaatccagg ctctcgaccg cgagcagcca gtgttgccga tgatgcctgg cgtgccggaa
  1308541 cggcgcacgc attcctatgt ccgacacggc acaaccacgt tgtttgccgc tctggatgtc
  1308601 gcctccggct ttgtcatcgg caaatgctac aagcggcacc gtgccaccga attcctggat
  1308661 ttcctcaagc agatcgatgc gagcgtaccg tccgatttgg acgttcatat cgtgatggac
  1308721 aactatgcga cccacaaaac tgcatcggtc aaaaactggc tgatgcgacg gccgcgctac
  1308781 cacgtgcact tcaccccgac ctcggcgtca tggatcaatc aggtcgaacg ctggtttgcg
  1308841 gaactgaccc gcaagcagct ccgtcgcggc gtccacactt cgacaatgca gctcgaagcc
  1308901 gacatccgaa gcttcatcga acgccataat cagaacccga agccttacag gtggacgaaa
  1308961 tccgcacacg acatcctggc ctccgtcaaa cgtttctgcc agaaagtcca ggacttatga
  1309021 cacgaatttc gcattcagat gactagtgtt tgcactagta cttgcagtct tcagcctacc
  1309081 ccagcaagac ggccgtcacc ggaggcttac ctctacacgg cgcatattga tagagctatc
  1309141 ctgcaccatg atgtcttcga gcgatctcgc cggcgaagag acgaataaga ggcacgactg
  1309201 caaagacata gcgtcgccac aatcttctcg gatccgatgc aagccgatgc agccattcca
  1309261 gccctgcgtg ccgcatccaa attggggcac gcctcttggc tcctgtaagg aactccaggc
  1309321 tggcgccaac gcagaagccg acgccccgtc cttcgggatg ggccattatt gcgtgtgcta
  1309381 tcttctcgga ctgtggggaa ccgatcgcta tgaagacgaa gcgtgcttcc tcccgtgtgg
  1309441 caaaatcaac acaatccatt gacgctgcgg ggttggagta aacagcctcg gggggcacct
  1309501 tggcgcggaa acagacccgg gggtatgccc gctccattgc ccgcacaatc tccgcgttgg
  1309561 ccgcgatcaa cgtgatcttt tccccgtccc ggatcacaga gctgaagaga gcggctgtaa
  1309621 ggtccgagcc agtcacgaga ggcagatcca ataacagaag cctggccaat cttgagatcg
  1309681 gccggctgtc gcaaagcgaa agccaagcct ggtcgtaata gggggcgagc cctgcattac
  1309741 cattcaggcg tacgacatga tcgacatttg gggtaacgac gtaacggaat cttgcgtgcg
  1309801 agctgcagtt gtcgagaagg ctcaacaccg cttctttcct aatgccatca aagggcgcgc
  1309861 ccaagaaata atgtctacgg tcggcgcaat acgcctcccc catggaccag ggggccaagt
  1309921 cagccatcga cgttcctccc gcgagtgttg gcagcgcttc ggccacctct gccgggcgct
  1309981 ccccagactt gtttagaatg atatattcta gacgatggat ttactggcta aaagcagtcc
  1310041 tgtaagcatc agttagaagt agggaggtga ataaagcagg ttgaagacgc cgcgtattac
  1310101 gcgaaatagg taaatacagt gccgcataag gtatattgat ccgctgcgag tttattgtgt
  1310161 cattctcaat tcaagcgtcg gcgggagggg aaaatgctgg aaacattctt gtgctatgca
  1310221 atcttcgggt tgtcagcagt cctttcagtc ccgagtggaa tttacgcggt ggagtgctct
  1310281 atcggcagtc tgccgctaca aaggaggcga gtcgccgaat tcggcctgaa ggcaaatgct
  1310341 gcggtaacgg ccgttctggt acctgcacat aacgaggaaa gcggcatcgc cgataccctt
  1310401 gccaatatcg gcgcccagct ttgcgatcag gatcgcttga tcgtagtggc cgataactgc
  1310461 tccgaccgga ctgcggcact tgcccaggag gcgggggccg aggtgatcga gcggttcgac
  1310521 gtcgaccgcc gaggcaaggg ctacgccctt gatgccggaa ttcgccacct ggaaaaaatg
  1310581 ccgccggaaa tcgtggtgtt gatggatgcg gactgccgcc ttggggaaaa ggcgctggag
  1310641 aggcttagag cgtcggttct cgcgagcggc atgccgggcc aatcgcgcaa cctgatgaca
  1310701 gctcctgatg gtgccgcgcc taatcttttg gtcgcagaat ttgcgttcct cgttaagaac
  1310761 tatgtgcgtc cactcggact cgtccgcatg aacctaccgt gtcacgccac cggaacgggt
  1310821 ctcgcaatcc cgtggcatgc cttacgcggc gcggatgtcg cccatgcgca tcgtgttgag
  1310881 gacatgaagc ttgggctgga tctcgcgagc gccgggtatg cgccgcggtt ctgcgaggag
  1310941 gcacttgtga ccagccaatt cccctgctcc ggggaagggg caaacgcgca gcgccggcgt
  1311001 tgggagggag ggcatctgga gatgatccgc tcggagctac gctctctggt gaacccgttg
  1311061 gttctccgaa atcctgcacg cctcgcgctg gcgctggatc tcatggtgcc gcctttgaca
  1311121 ctgcttgtgc tcctgctcgc atctgtgatg ctgctttccg tcatgctcgc cgcatccggg
  1311181 ctatccagct ggccattggt cattgcgacg gtgaatctgg cccttgtttt cgtcgcaaca
  1311241 ctcggtgcct ggtacgtcca cgggcgcaag gcactgcctg cggcgacgat aagtagaatt
  1311301 ccactctatg tcctatggaa gttgcggctg tacccgcgcg ccctcttggg tgcgaatgag
  1311361 ggctgggtca ggactgatcg cgacaaggac gtttcgggag aaagccgaac ttaggctgcc
  1311421 ggatgatcgg cgcaaccagg ggaccggcgg ctcaaaggct tcaccccaca tctgtcggag
  1311481 gatcagcgcc aggactattg tatgcgttct atcgatacgt cactcaacgc gctctacgcc
  1311541 gtcggaagca cggacaatgt cgtcgtcgcc gagataagag cccgtttgta tttcgatcaa
  1311601 ttcggtaacc gtgttgccgg gattggccaa cctatgctct tcaccggtcg caacacatac
  1311661 ggattcattc tcgttcagta tttgcacccg gttcgcaatg gtcacttccg cagtcccttt
  1311721 gatgacgatc caatgctcgc atcgatgacg gtgccgttgc agtgaaagcc tttttccagg
  1311781 tctgacggta atccgtctga cctggaaatg ctcgccgttg aggatcgtcg tgcaatcgcc
  1311841 ccacggtcgg caggtcgtcg ggtgcaactc cgtgagacgg gccgtctctg gcgcggctgc
  1311901 gaggaggctg acgaccttgc gcacgttctg actgtcgtgc aggcggccta catagaccgc
  1311961 gtcctcgctg gcgattacgg cgatcccttc gagaccgtgc acagcgaggt gcgcgccctg
  1312021 ggtcataatc aaggagtttc tggtgtccgt tagcgtcgtg tgtgcggaag cgacgttgtg
  1312081 gttctcatca tgccgaccag tcttccaaac cgcatcccag cttccgagat cggaccatcc
  1312141 aaaggcagaa ggcacgacca cagcccgcga cgtcttttcc atgactgcgt aatcgaatga
  1312201 aatatcggga catctttcga atgcatccgt atcaagcagc acacaatcgt gatccgcgac
  1312261 cgatttggac acagccaggt ttacagcctt taggacctca ggagcgtgtt cggcgatctc
  1312321 gacgagaacg gtcgacaggg agaacatgaa tatcccggaa ttccagtaga agccgcccgc
  1312381 cgacagcatc tcaagcgcat ttttaaaagc cggcttttca acaaaacgac tgaccttgta
  1312441 ggcgccgctc gcaagtgctt ccccaacctc tatgtagccg tagcctattg ccggctcggt
  1312501 cggcgtgatg ccgaaagtgg ccaacttccc gtcggcggcc tcgagtcgtg cgatcaagtg
  1312561 agcttcgtga tacgaatcat caacgttgat atcgtggtcc gatgcgagga catgaatggt
  1312621 tcgatcttcc ttgaagaggc gagatatgac caaggcagcg gcagcaactg cggcggccgt
  1312681 attgcgcggc acaggttcaa gcacgatcgc actcaatgcg acacccatct cgcgcgcctg
  1312741 ctctgtaaca agaacgtgga agctttcatt cgtgatgacc accgcaggct cgtaaacagt
  1312801 ttggtccgag acgcgcagaa gtgtgctctg gaacagcgta tagtcgttga cgaactgcat
  1312861 gaactgcttt ggcgctgccg agcgggagag cggccaaagc cgtgtaccct tgccgcctgc
  1312921 catgattacg ggaacgattc ttctggtcaa ttgaggatat cctcgtgagc agcctgttgc
  1312981 ttgctaaatt cgttcgtcca aagcctgagc cgggcaaggc cggcattcaa caagtcccat
  1313041 gccgcggtct cagtcgccgc ctcggcatag cagcgcaatt ccggcgcatt gccggatggc
  1313101 cggaaatgga tggtgcgcct ttccgtcagc gttacccgaa ggccgtcgat gtcgttcgcc
  1313161 gaagtcacct gacctacatc gcgcaagaag accgagatgt tttcgaagga acgcaggtag
  1313221 ctcatcagag cagtgctggc ctcgacggga tagttttcca aacgacctgc agccgcggca
  1313281 ggcaggtggt atgaccgtgc gacgacggac agcggtcgtc cttgcgactt cacttgggag
  1313341 agtacggcca atataggcag gatacagtcc cgcgttggca gtgcctccag gcgatacctg
  1313401 ccaaggtcaa ttgtacttgc cgtcaacact ccgccattgg cttcgaagcc gataaccgga
  1313461 tcgcctgatg cggccgaggc ctgttgcatc gctgcaatca cgaagggcga gccgactttc
  1313521 gtgcgtatga cggagaagaa gccgagtgcc tcaatccctg agttcgatgt gatgggcgtg
  1313581 acgatggtct ttgcgccgag aaaccgggct gtcatgaggc caataaggtc tccgcgcagc
  1313641 ggccgaccca tttcatccgc aatgagcggt ctgtcgccgt cgccgtctgc agaaacgact
  1313701 gcatccagcc catgcgagcc ggcccactcc tcaagcgata taattgtctg cggtgagagc
  1313761 gcttcggtgt cgaccggtat gaatatttcc gagcgtccga gaggcaccac atctgccccc
  1313821 aatcgcaaaa gaagcatcgc gatcagatca cgagcaacgc tgctgtgctc atagacaccg
  1313881 accttaaggc cggccaaagc accgccggag agtagccttg cattcctctc gtaaaatagc
  1313941 cggaggcatc tttccgcatg atcttcgaga ggcagaacgg tgttgtccct cgggacatca
  1314001 ctttgcgagc ggtaatccgc tgccaacgcg gctatcgccg tttcatccgc tttgttgatt
  1314061 tcgccgttcg gacaataaaa cttgatacca ttgcggtccg cggcaatatg cgagccggtg
  1314121 accattaaac cggcggcttc gagcttcgaa gcatagaacg ccagagccgg cgtcggaacc
  1314181 gtcccacagt cagcaaccct gaagcccagg cgttccaaca cggtggcgca aatcattttg
  1314241 atctcgggac tcgagtcgcg cagatcgttg ccgatcaaga tggcgtcccc cgtgcgaacc
  1314301 tttccgagct caaccaggta gcgaccgaat gcccccgcat aggccctcgc accaacttcg
  1314361 acgagatcga ctgacaggcc gcgaaggccg ctggttccaa acttcatgtc gtccagcttc
  1314421 ttcagttgcg aacggttacc ccgcactggg gctcatgcag tcttgccagg agaattatta
  1314481 tattaagagc acgataggta taatttgaac gattgagctt ttctcctcct atagaggcga
  1314541 aatagaggaa acattcgacg taggttcaac tgaccacgcg ctcatctctt tctacgtcga
  1314601 aagaaggata gcctccgcag ttgccggctt ttccatctaa tggatgcttg tccgggcgcg
  1314661 gctattcatt ccatttggcg aatggagcgc gcggctacgc ctgaatacaa tcgcgccatc
  1314721 tgcgccgttg acgagcaaag agcttgccaa cagcagcgtc ggtagggccc tcccggctgg
  1314781 atgtctcgct tgcgccacgc cggggggaag gggggattat gacatcactg tccgttgtta
  1314841 cgccaagcta tcggccggac ctcgaattgt gccgagactt gaatctgtcc gtgcgaagat
  1314901 ttggtccgtc gggcgtcgcc catcatgtca tcgttccggc tgccgatcgc aaagcgtttg
  1314961 ccgggatcgg cgatgtgcat gccgtcgacg ggtacctgcc gagaagtttc gtccacattc
  1315021 cagggaacct ctgggtcaat ctgcgttccc caatactccc tgtgagaggc tggatcgccc
  1315081 aacagttgat caagttagaa ttcgtcgccc ggtcacagga tagcgtggtg ctcctggtcg
  1315141 actcggacgt gacgttcata cgtccgtttt cggctgatac attccaccgt catggcgagg
  1315201 tacgattttt tcgtgcagtc gacgcaatac atgcgggctt gcccaggcac atatgctggc
  1315261 accgagtagc ccgagagctg cttggagtgc gtagctgcga tcgtatgccc ctgaacgact
  1315321 atatctgctg gccgatggcc tgggatccca gtgtcgtacg ttccatgctc cggcgggtag
  1315381 aggaggtcac cggcaaaccg tggcaaaccg ccgttgcttc gcaacggcac ttttccgagg
  1315441 gcattctcta cggcgtctat gtcgatgaga tcttgggtgg gatgccttac tccgagaata
  1315501 cgatgctgtg cgtgaactat tatgatgaga ccccttttga ggagatcgaa aaatttgcat
  1315561 cctatattac gccgaacgac attgcagtga tgatttcggc gaagtccgga accagtcttg
  1315621 cgtcccgtag gcgcgcgctg gccgcaatcg ctgcctccgt cggcgcagat atccaccaac
  1315681 agggcgccac atgaactctg tccaaacgat cggaatggcc tccggcatcg gctcgccggc
  1315741 atggtcccgc ccgcatcact ccgatgccat ctctgcggcg acaaatccca gtctgcattg
  1315801 gtatggatcg aagcggaccc ctgaaaggtc ccagggcgaa taggtgagtt cggcagtgtc
  1315861 gtctaaaagg ttcaagacaa tcttgtatgc gccgcgcccg gtttgaattt cgcagccttc
  1315921 aaatggaaag ggcagacctg acgcacccca gccgctttct gattttaaaa gacgcgacgg
  1315981 tcggcggcca cctttggcat catccataag gatgtcgtgg atttggtcaa tctgcgcatg
  1316041 aagaactgcc atctcccgca gtatctctgg tcgggcgtca tcgtatgaga attccggaga
  1316101 gaacttgaac gaaaagtaaa tgagcccggt ggccccatgg atgatcgatg accacgcctg
  1316161 cgctcgaaac tcggccggcg ttggttcgcg gcctacctct ccattgtatt gtgtcagacc
  1316221 aacgaacgag aattgcggtt tgtcgccact ccaacgcgat attctgtcaa ttgcgtggcc
  1316281 ctggtgagtg gatgtgtagc cattgagttc caagagcaat gtatcgcccg aggcgatggg
  1316341 gtaacagtcg tgactcagcc aatcgatgta ttggctatcg gcgtagtcgg acatgattcc
  1316401 gtcaagatgg acgttgttga tgtggttgcc gacgtgattg atccaaagag cctttcctcc
  1316461 aagtgaccag tcgcgggcga ttacatcgat ttcgtcgggc ttcagcagca cctcttcata
  1316521 ggtgatgtcc tttccctcgg gcttgaggtt ggaaggctcg tccatcaacg agaaggccag
  1316581 caagccgggt tcagtgagat ccagttcgaa agcggcgcga tccgccacca aaaagctcgc
  1316641 gccggagaca tcgattccgc gaggctcgcg caccatgtaa acgccttgcc tgtttgcttc
  1316701 attcgtccat tgcgtaacgt cgccgccgcc gtttaccgcg aacagggtgt tgaccccgcg
  1316761 ggccttccat aatgcgattt tctcgatcgg ttgctgccaa atgccggtga tgaagaatgg
  1316821 gggcaagttg ccatggaaag acctcgcttc cgcggcgatc gcgccgggga tgctgaggcc
  1316881 acaagcagcc tcggtgaagg gcagcaagga tgccaagcgg aggaactggc ggcgacgaac
  1316941 aggcatgatg agacctttcc cagcgctcga tcaagctcac tccgccaacc gctggccgat
  1317001 ctaatgatac cgaaggttcc cttgcgagag gactcacaat aatgggtatc cctttaagcc
  1317061 gaaagacttg atccgcgccg ggcacctttt cgcttagatt gagatcagcc ttgagcaatc
  1317121 catggcgaac gacacctatg atgacgcccg caaatggcgc gggcacgtgg acatagggtg
  1317181 cggaaagttt cgcgctctgc ctcaggtccg gtgcagccct tgtcgggttt tccggcctca
  1317241 tccggctccg aacggtggcc aaaatttgag acgtcggcga tgtcgataat agcaagcaga
  1317301 gcgggtgaag caggggcgaa ggggaagaca gccctaaatc gcttgctgat cattttgttt
  1317361 gtaaccgcaa ttgcggttcc gtggatcata ccggtcggcg ccctccgcat gtctgcttac
  1317421 cgcatgactt tatgcatcgt agtgatccct tgcctcgttc attggttgag cggacgcgcg
  1317481 gggccaattc gattcagtga ctttgcaatc atcctgttcg ctttttggaa ggggctgtct
  1317541 ttagcggttc tgcacggcga agaagccgtt caggcgatag gaatttcctt cgtggaaacg
  1317601 ctcggacctt atttcctagc ccgctgctgc gtacgcagtg ccgaggactt tgaggttttt
  1317661 gcgaaagctt tgttcgtggt gatcgcagcg ttactgccgc ttatattgtt ggaaacggtc
  1317721 actgggtgga aggcgacgtt aagaatcttc gcctttgtgc ttcccactta tcccgacgac
  1317781 cccatgatgc gtgcgggctt ctggagggcg caaggcccat ttgagcaccc tatcctgtgc
  1317841 ggagtggtat gcagcgtggg ctttgttctc gcgtttctgg tcctcggtta cgcacgacct
  1317901 cccctggata gatactctaa ggcgggaaca attgccttta ctgtagcact ctcgctttct
  1317961 gcaggccctc tcctcggcat tgcactacaa tccttgctga ttgcctggaa acgcttggca
  1318021 gatgccatcg ggccgcgacc cctctggctc atgaccgtta ccctttccgc gctggcgctt
  1318081 tgtacaagct ggatcactgg ccgctcactc gtcgcgctgg tcggcagact taccttcgac
  1318141 cccatgtcct attggtctcg caatttaata tgggaagtcg ggtgggtgtc agtttcaaat
  1318201 catcccgcat tcggaaccgg tcttggcaga tgggatcggc cggaatggat ggtctccagt
  1318261 atcgacaatt tctggctaag cacggcggtg acccatgggc tcccagcact tctttttatc
  1318321 attgcgtcgg tagcgatctg ccttgtcgcc gtcggccgga aaacgggact gcatgagaaa
  1318381 cttagagagt atcgatcggc ctacgttatc tcggttttta gttggtgcgc tgtaggtcag
  1318441 accgttcacc tttgggacgg cgccctcgtt atcgtacttt ttcttcttgg aagcgggctg
  1318501 tggttgctcg acgtcgacgc gaatgaggcg catccgtacc ccgcaagtga ccgtttacgg
  1318561 cgaaagcgca tcgattccgt cggcgttcgc cgccccggcc atcgtcgccc gcccagaggc
  1318621 agccgaagaa gccccaattt ggctgaacat cgtttcggcg ccaccatccc gaagcattat
  1318681 cctggaccat ccgaatagca ccaaagtcgt atatttttag ctaacagcaa atattttaag
  1318741 gataaacaat gagacgtggc ggtctgtaag atagtctaga tcgaattgtc taaagatgat
  1318801 ctattgatgt ccatcgggat tatttactag gatttgctta cacaagcggg gtttaatgac
  1318861 aaagatttta tgtacagcta tttggctgtt ttctggttca tgaattttac cttgaattgg
  1318921 aacaggcatg tctccgcgtg tgggggtcca ccagtcgatc ctggagagca cgatgtggag
  1318981 aaatcccaaa ttaggtccgc aactgtttgc aacgctgccg gccccttacg atgaaacgct
  1319041 gcgatcgcgg tcgtcgtatc tcaaagccaa gcgcgggttc gatatcctgg tgacgttgct
  1319101 gatcggtcca ctcatcctgg ccatcgtcac cgttctggcg ctgctcgttc gcctggacgg
  1319161 cgagaaggcc ttttattttc agcctcggct aggcaaagga ggaggggtct tctgtctctg
  1319221 gaagcttcgg accatggttc ccgattcaga gcgtaagctg caggagtatt ttgaggctga
  1319281 tcccgcggcg cgaagcgaat gggacaggac acagaagctg cgcaacgacc cccgtgttac
  1319341 gcgattaggc aagtatctcc gcaagtattc ggccgacgag ttgccgcagc tgttgaacgt
  1319401 gctcattgga gatatgagtc ttgttggccc aaggccgata ttgccggaac agcggcggca
  1319461 ttatcccggc accgcctatt tcaccatgcg tccaggattg actgggcttt ggcagatcaa
  1319521 tgaacgcaat tcgtgcacat tcgccgaacg tgcagcatac gatacgcgct atgctggttt
  1319581 gatgtcgttc agcgcggatc tcctgatctt gttgaaaacc gtccttgtcg tcctgcgggg
  1319641 gaccggaatc tgagggaaca gtctgcgcag gcgttttcgc cggtcttgct tcacgggtcg
  1319701 agccaattcg ttccatcgac cggagtatca gccggaaaga gatcattgat cttgaaggca
  1319761 acttcggttc tgttcgtggc cttgaccttc ttcatgatgt tgcggatgtg aactttgacg
  1319821 gtgctttccc gtagattgag ctcatatgca atgatcttgt ttgccttgcc gcgccgcaga
  1319881 gcctcgacca cttcggcttg gcgagctgtg aacataccag ccagagggtg cgcgacggcg
  1319941 ttaccagtct ccaatagccg gcccatcgct aagatgctgc tggcgggaac aaaaattccg
  1320001 cccgccagcg caaggccaat tgcttcgatg cagacatcta tgctgacgga agaaggaatg
  1320061 tagcccttgg ctccatactc gagtgccttc acgacctgcg caagctcatc cgtatctgcc
  1320121 agtacgataa ccggtgttgt tgcgaactcg gacgacagtt ctcgaatttc cgcggtgatg
  1320181 aaaggctcag cgatccttct cgctccgaca ttcagcaaaa ttgcagaggg cgctgggtag
  1320241 ttgttgcgat gctgacccca gtccaccatc gttcctaacg ctaagacctg catatccatg
  1320301 ttgtgagcga tgatgctctg cgcgagacat tggcggtcaa gtgcgcgact atcgatgatc
  1320361 acgagcaggc gttcgtgatt gtcagttgct cctgcgctat ctctagccgc cacaatatga
  1320421 tcaattctgt cgtggtttat ttcgttctca ccaatcatgt ccgaagccat gttcacttct
  1320481 ccccacggaa cattctgatc tcgataattt tttcgagcgg actacacgga aatatttttt
  1320541 ggacacggca atgtctagaa tccaactgga agattggcca atataacgct gcgaatacta
  1320601 tcgcggtcta cagcagcatt tccgcagcag ctgtatcgct gaggttgttt acgcactgga
  1320661 actcgcccct agtttgcccc attccaaggt cggttaaaga cctatgaatt tttacagtag
  1320721 acatacctct ttcgcggtaa gacgttgcaa gttccctgta cgaatggtgt acctcgctcg
  1320781 tgcctcccct cacgcacatt gacatgtcgg cggtgcactc ccgtgccaga gcatgcacgc
  1320841 ccgcgagacc aggaggcatg atcggtacgc tgaacatatc gcagaatata tcctgcccgg
  1320901 tgcaatcaaa agcaatgatg acagtcttcg atcaaaaagg ccaattgggt cgctggcgga
  1320961 taaagtagtg tgtcgtttgt atatgatcat acatgagttt tattgaaaac tatacattat
  1321021 tagcactatg agtattggaa acgcgtagag ggatttcaat cgtgacggct ttctgtcgtc
  1321081 ttatacccat ttgccagaaa ggaactgcgc agtgtttttg ccatcacagc ctcttgcggc
  1321141 acgtcagatc attttcgcct ctcgcagaat tgctctagac gccgatctgg ccgcgacgcc
  1321201 accggcggca ccattcctcc aggcgccagc gcaccgccca tgccggccat agagcatgag
  1321261 caggaagcct gcctgttccg tcgtgtctcc ttttggcgag cacttttccc gctctggtgg
  1321321 acgcagggct gtggtggatt tctctcgcga gagcctcgaa ttccgttgtg ggaaaatcac
  1321381 gccaaccttt ggcatgggca tagttgatgc gctccagcac ctgacgcgcg atggtgctgc
  1321441 gggcaagctc cagcagttgt ggtccctcct ccagcccaga tccaacgccg ctgaataccg
  1321501 cttcgaagga ctgccagcgc tgtttgaggt cgatcagctg accgagggcg gtgcccgagc
  1321561 cgaaatcctg tttgttcata ttggtcgcgt gatgtcggta ataggcctga tcaacgccgg
  1321621 caaggaagcc gatgtctgac actgcagagg tgcgaagcca catctcgaag tcgccagcat
  1321681 gcggcaggtc ggcgcgatag ttgccgattt cgcgcagcac tgccgtgcgc ataaccgcct
  1321741 ccggggaggt gatggtattg aatcccgacc ggcagcggat ccgcagccaa tcgacgccgg
  1321801 gccatacgat ccaactccct ccggcaattc ggctctcggg caactcgcca tggaagtgga
  1321861 tcgcgttacc ataaacaagc ccgacagacg gttccgcagc aaggaattca gcagcacggg
  1321921 tcagtgcacc cggtgtcacc agatcgtcgg cagaaagtaa cagcacgaat tcgccggtcg
  1321981 cggcttccag cccgtcgtta taggttgcaa tgtgaccctt gttttgtttg tgcgctatca
  1322041 agtgtacgcg cttgtctgca tcctggattg agcgcgccac ataggcgcta tcgtcagtcg
  1322101 atcgatcatc cacgatgatg acttcgacgt cgacgcctgg ttggttcagc gtgacgcttt
  1322161 cgacacattg ccgcagataa cgtccgtagt tgtagcaagg aacaacgacg gtgacgcggg
  1322221 cgatccgatt tagcgcgcgc ggttcctcga tccgcccgtt ggcgagcttc gctgccgtgc
  1322281 gcgtgagaat atccacgttc gtatcctcca ctcaaagagc ctgccggagc gccacgcgaa
  1322341 atgccctgtc taccgccgcc cccgccatgt tccaggacgt tggcgcaacg ctctcggatg
  1322401 ccttcttcga tacgcttgca aagtcaggca tgctcaccac gctctccaat gcggccgcaa
  1322461 gcagatgggg cgtcagtgga gcgtaccgca cgtacgagtt atcgaggaca attcgatttt
  1322521 gcaccgcgtc gttgacgacg gggagacagc cggacgcgag catctcctgc ggcacgagcg
  1322581 agacattcgt cagcgagagg ctcaggccgg caaaacagcg attgtagatc tcgttgagcc
  1322641 tttgggggga tacgagccca tgattggtga cgcggaacgg cagattgtcg aaccgctcgc
  1322701 cgaacaggtg caattcgatc tggggttgcc gttttgcgaa caactcgagt gccagaaggc
  1322761 ccagctcgac ggcgcgacgc ggggtaccga cccgcgcgta aaaagcgacc ccggaccgct
  1322821 tcgaggcggg gtcccggcga tacagggccg tatcgcaacc gaacgggaaa tagtcgctct
  1322881 gcatgccgaa ctcccgggcg agcttttcag ccaaccagcg cccagcggtg atgccatgga
  1322941 agcccattcg ataggtgttt tcggcaagca cactgtttgt gcccaccgga tagaagtatg
  1323001 gttcgtagtc ctgaacgaaa tagaaccgct tgccggcgca gcgcgcattg aagacggcgt
  1323061 atgccgttgg ccaactcgtc gctaccagtg cgtcggcatc cttcatgccg tcgcggatgt
  1323121 cgcctatctc gcaggtgagc ccataatgct cacgtgcgag cccctgatag tacttgggat
  1323181 cccctgcgta cggatcgtac aggtagacgc ggttcaaata gccgctattc tggagttgct
  1323241 tgacgatcct gtacagtgtc gtgtgtccgc ccgatccgcg tccggccggc cccgttaccc
  1323301 agttcaccgt tatcggggcc tcccgatcga tctccggaac ccgtgcgcag aagggctgtg
  1323361 agaggtcggc ggcgataatg tcatcgggaa caactggcca gaccggctcg cgaggtctta
  1323421 tccagtccga tgccttgaat ctggcgcggc agatgacccc ctgaaaccca gtcgtcgcca
  1323481 caatgtggct gatctggcgg gtgcggcgac caaactgccg cggtatttca cggaagaccg
  1323541 aagcggccgc gccgcaaagg gcaaagccct ctttcattgt tgcgctcatc gaaaagatct
  1323601 cgcgctgcaa agacgacctc ccgcccatct cgagcatctc cgcatttcct ggaattgctt
  1323661 tcaagcaatt gcggggccga caggctcaaa gcgaccgtcg cggccgcccg agcgattgcc
  1323721 gaagcgctct ccattgtggt ggccgtccgt tgcgctgcaa gctctcactt cggacgagga
  1323781 acgatggcgg cgcagttacg gcagacgaag cgtacttgag cgaagtcatc aatgggtctg
  1323841 cagaattagt acgcctttcg gtgcactcaa tactgccttt gttttcttta ctcgtgcggg
  1323901 caaaagaatt cttttggaga tcagaagagt tcggtgatct gccacgaaat cacgacgaaa
  1323961 gcgcggcggt gcagctgcgg gcgatcaaca cataacgcaa caggggtggg cagcatgatt
  1324021 gccaacgacg tcacgctgca tgacggtgtc gtggttcatc atccggatct cgtcaatctt
  1324081 tatggttgta cgatcggctc gggcacgcgc attggcacgt tcgtggagat ccagaagaac
  1324141 accacaattg gccggaattg caagatttcc agccactcgt tcctctgcga gggtgtgacg
  1324201 ctcgaagacg gcgtcttcat cgggcacggc gtcatgttca cgaacgatct ctatccgcgg
  1324261 gcaatcaacg ccgacggagg acgtcagtcg gagggcgact ggacggttgt tccgacgcgg
  1324321 gtcaaacaac gggtctccat cggcagcaat gcgaccattc tcgcaggtat cacgattggc
  1324381 gaaagcgccc aggtcggtgc tggcgccgtg gtgaccaggg acgtgcccgc ttacacgatc
  1324441 gtcgccggcg tacccgccag gatgatcgga cacaccaagg atgcggcggt caatacggtt
  1324501 cgggcggggg catgagatga tcggtgttgc tgtcgtcggc tatggttact ggggaccgaa
  1324561 cctcgtgcgc aacttctggg agatacccgg tgcatgtctt gtcgcagtat gcgatctccg
  1324621 caaggatcga ctggtcgcag tccagaaccg ttaccccgcc gtccatgtca cggacgattt
  1324681 cgacgaactt cttcgcaatc cacggatcga cgcaattgct atcgccaccc ccgttgcagc
  1324741 gcatttcaag ctggcaatga agacgctgat ggccggcaag cacgtcctcg tcgaaaagcc
  1324801 gatggcggca agttcggacg aagctcgccg catgcttgag gaggcagcac gtcgccgcct
  1324861 cgtgcttgcc gttgatcata ccttcgtgca caccggcgcc gtccggaaga tgcgtgacct
  1324921 cgttcaggat gggctcggcg acgtctacta ctacgattcg gtccgcgtca atctcgggct
  1324981 gttccagcgc gatgtcagcg tcatttggga tcttgccgtg catgatctgt cgatcatgga
  1325041 ctacgtgttg ccggagcggc cagtcgcagt ctcagcgacg ggcatgagcc atatcgccgg
  1325101 cgaaccggca aatatcgcct atctcaatct tttcttcgag agcaagctga tcgcgcacat
  1325161 ccatgtcaac tggctcgccc cggtcaaggt tcggcgcacg ctcgttggcg gaagcagcaa
  1325221 gatgatcctc tacgacgatc tggagccgag cgagaaaatc aaggtctacg acaggggagt
  1325281 gacgctcaac gacagtggcg aaaaggtcta ccagatgctg gtcggctatc gcaccggcga
  1325341 catgtatgcc ccccacatcg acgtcgccga agctctggag attgagctgc gtcagttcgt
  1325401 cgagtgcgtc gagcggaaca aaacgccaac cgccgacgga aatgccgggc tgcgtgtggt
  1325461 caagattctc gaagctgcca gccagtcgct cgccgagcgc ggccgagtgg tcgagctgga
  1325521 gcatatgagg cgcatcgcat gatccccttc ctcgatctca gggcgcagta tgcatcgatc
  1325581 aaggaggaga ttgatgcggc ggtgcttcgg gtgctagcgt cggcggaata tgtcctcggg
  1325641 gatgaggttg cagagcttga gcgggagttt tccgcttatt gcggcgtgcg gcacgcggtt
  1325701 gccgtcaata cgggtacgag cgccctccac ctcgcgctgc tcgcgctcgg cgcaggccct
  1325761 ggcgacgagg tcataaccgt gcccttcacc ttcgttgcca cggtctcggc gatcgtatac
  1325821 acgggcgcgt tgccggtttt cgtcgacgtc gagcctatga cgctgaccat ggatgcgacg
  1325881 aagctcgagg ctgccatcac gcctcgaacc aaggcgatcg ttccggtcca tctctacggg
  1325941 cagatggccg acatggatgc gatcagggcc atcgccgacc ggcatggcat ttcgatcgtc
  1326001 gaggatgctt gtcaggccca tggcgccgaa tacaggggtc gccgtgcagg aagcatcgga
  1326061 gtatccggct gcttcagttt ctatcccgga aagaacctcg gtgcctgcgg agagggaggt
  1326121 atcgtcgtaa caagcgatga gggtcaggcg cgaacaatgc gcatgctccg tgactggggc
  1326181 caggaaagcc gctatcacca tgtgctgaag ggctttaact atcgaatgga cggcattcaa
  1326241 ggtgccattc tgcgggtgaa gctcaggcac ctcgatgcct ggactcgggc gcgtcgggcc
  1326301 cgtgcggccc tctattcctc cctgctgagg gaggcaaact cggtgagggc tccgatagaa
  1326361 gccgccggca ggagccatgt ctatcatgtc tacgcagtcc gttgccggga tcgtgaaggg
  1326421 ctcaaacgtg ccctttcgac ccaggacatt caatacggct tgcattatcc tattcccgta
  1326481 catctgcaga aggcgcatgc cgatctcggc tatgctgagg gcgatttccc gagatcggaa
  1326541 gctgctgcct gctgtgtgct atcgctgccg atataccccg aaatgacgac ggggcaggtc
  1326601 gagcaggtcg tatccgccat ggagcagaag gcctatgtcc actgagcgcc tgccaaagtc
  1326661 gcgggtcgtg ccggcggttc atggtagccg ccgggctagc ggcgatcctg gttacatggt
  1326721 ggaactggca ggggtgctcg gacaagccta tggcctggga ggtctgatcg agctctacgg
  1326781 acgcttcatg acgggggatg gcctcgtcga tgcgctgatg cgtcacgtga tctggcgaag
  1326841 cgtggtgagg cggtgcggca gcggtctgca ggttggcagc ggcgccgaat tcaagcatcc
  1326901 tgaaaccttc gagatcggca acggcgtgtt cattggtgca caggcttata tccagggtcg
  1326961 tcatgacggc agatgcgtga tcggcgacaa tgtctggatc ggcccgcaag cctatctcga
  1327021 cgcccgggat ctgatccttg aagattatgt cggatgggga cctggggcga aggtccttgg
  1327081 ttcgagccac accgggacac ctgtcgatgt gccgatcatc ctcaccgatc ttgaaatcaa
  1327141 gccggttcgc gtctgcgcat gggccgacat tggcacgaat gcgaccatcc tccccggcgt
  1327201 aacgatcggg aagggcgccc ttgttggggc gggcgcagtc gtcgtccgcg acgtcgaacc
  1327261 ctttgctgtc gtagcggggg taccagcgaa attcctgcac tggcgagcgg atgctgcggt
  1327321 gcctacgaaa tcatgatcga tcgggggggg ggcggacaat gaaaaacaag cgagtactga
  1327381 ttacgggcgg ggccggtctg atcggctcac acattgccga tctggttgcg ctggaagagc
  1327441 ctcgggagat cttggtcctc gacaacttcg tccgcggccg ccgggacaat ctccggcagg
  1327501 cactgagcac cgggctcgtc agaatcatcg aaggcgacat aaggaaccga acccttcttg
  1327561 cgcactcgtt ggaaggcgtc gacatagttt ttcatcaagc ggccattcgc atcacgcaat
  1327621 gcgccgagga gccgaggcta gccttcgatg ttctggcgcg cggcacgttc gatgttctcg
  1327681 aagccacggt tgcggctggc gtgtcgaagg tgatcgcggc ctcctcggcc tctgtgctcg
  1327741 ggctcgccca atgttttccg acgcctgaag agcaccaccc ctacaacaac cggacgatat
  1327801 atggtgccgc caaggcgttc aacgaagggc tcctgcgcag tttcgcggaa atgtacggtc
  1327861 tcaaatatgt cgcgttgcgt tacttcaacg tctatgggcc gcgcatggat gtccacgggg
  1327921 tctatacgga ggtgctgatc cggtggatgg agcgcatcgc cgccagccgc ccaccggtca
  1327981 ttttcggcga cgacggacag acgctggatt tcgtgcatgt acgcgatatc gctcgggcca
  1328041 atctcatggc cgcgaagtcg gatgtcaccg atgaagtgtt caacgtggcc agcggcgagg
  1328101 agacgagcct cagagcgctt gcgctgcttc tggcccgcat catgggaacc tcgctcgaac
  1328161 cgcagctcga gccggcgcgc aaagtgaacg cggttacgcg ccggctggcg gatacacgca
  1328221 aggccgagcg gcttctgggg tttaagacgc agatcaccct cgaggagggg ctgcgcgatc
  1328281 tcgtcgcctg gtggcggcgc gagcagacct gcgccggagg agaggcggca tgattgcggc
  1328341 gtgcgggcaa atcccggtcg ccaaacccct tcttggcgaa caggaagtgg aggcggtccg
  1328401 gcgtgtcatt ctatccgggt gggtgacgca agggccggag gtcgcggcct ttgaaaagga
  1328461 gttcgccgat tatgtcgggg cggctcacgc ctgcgccgtt tcgagctgca cgacggcgct
  1328521 tcacctggct ttaagctgcg ttggagtcgg cgttggcgac gaggtgatta cggcaagcca
  1328581 ttccttcatc gcgactgcga acgccatccg ctactgcggc gccatgcctg tcttcgtcga
  1328641 tatcgaggct ggaggctaca atatcgaccc cgatcgcata gaggcagcca tcacaccgcg
  1328701 gaccaaggcg atcctctgcg tgcatcagct aggcttgccc tgcgatcttc gccgcgtcgt
  1328761 caatgtcgga aagcggtact ccattccagt gatcgaggat gctgcctgtg ctgctggcag
  1328821 tgaaatcctg tggtacggcc agtggcagag gatcggcaaa cctcatgggg acatcgcgtg
  1328881 cttctccttc catccacgaa aggtcgtgac caccggcgac ggcggcatgc tgaccacgtc
  1328941 aagtgaggaa tacgaccgaa aactcaggct atggcgtcag cacggcatga gcgttccgga
  1329001 cacgatccgg cacggggcga aacaggtgat atacgaagac tatccggagt tcggctacaa
  1329061 ttaccggatg accgacttcc aggcggcgat cggccgcgaa cagttgaagc ggctccctga
  1329121 actgatcgcg cggcgcaggg agattgcgca aaaatacacg tggcatctct cccgcctggc
  1329181 gggtttgcgg acccccgccg agcccagctg gaccaggagc aattggcaga gctattgcgt
  1329241 tgtattgcct gaccgcttcg atcagcgcga gacgatgcag gccttgctcg atcgcggcat
  1329301 ctcgacccgc cgcggcgtca tgaacatcca tctggagaaa gcctattccg gaagtggcac
  1329361 gtatcgggct gcaacgaccc tgacgcggag cgtcgctgcc cagcggacat cggtgatcct
  1329421 gccgctcttc gcccagatga cggacgccga gctggcgcat atcaccggcg agctttcctc
  1329481 tattttaggt tctgccgatc cggcagcctc gcgtaccgtg tgacagcagc ccacctcttc
  1329541 atttgacctt ttcgcacagg tcaggtcgac cgggagcacc aggcgcggac tgcggccggc
  1329601 aaggacggca gccggacgag ttccatgagc atccgcagtg aataggctcc gctcagcgcg
  1329661 gttgtcagca tgccgaatat cgtcgccggc caaggcggca gagcgacgaa agcaccgaag
  1329721 acgaagcctg acgcaggcag gaagaacagg gctagctttc ggttggtggc ggaccagcgg
  1329781 aagtccgaga ggtgacgtgc gatcgcatag attagcaagc cgtgccagac atatagaccg
  1329841 acaaacgcca ggcctgcgcc ggccgatcca aacacgccca cacagagcca tgcgaggccg
  1329901 acatggacca cggttgccgt aacctccgtc cagaaaaagg ctctcctggc accttttgcg
  1329961 agaacgatga accccattgg ccatgaaatg atccgcagca tcatgcccat gcagatccag
  1330021 cgaaggagtt ccacagcggg gtagaattcg ggcgaataca gcagcctgac caccaatggc
  1330081 gcggcggtga gcgttgctat gaggccaggg ccggcgagta gcatgctgac ctgggcttgc
  1330141 tcgttgacga ggcggttgca ttcgccattg tcttccgcca ccgccgtcag gcgcgggtag
  1330201 aaatcggttc ccatcgcctg caggatgaag ccggcataga gaccgccgag tgtccaggct
  1330261 gcctggtaga ggccggccgc cgtcaagcct tcggcgcgca gcacgaagat gcgcaccgca
  1330321 taggctgcgc ccaatgttag aaagctgctg accatgaagg cggagccgag cttcaagagg
  1330381 gcttccacct ctcggcggag ttgtgctgtc gacatcgggc gcgcggttac ccgcagtcgc
  1330441 cggccgtacc accaggaggt cgcgagcgaa gccgcagcaa cgaccacgag cgagggcacg
  1330501 atgcccgacg cgccaaaaaa atagatcagc gggattgtga caaccgtgct gaagaaggcg
  1330561 gcgaggacat tgatgcgggc aaggctggcg atatctcgca tgccctggat caaggcagtc
  1330621 tgtccgtccg ccagcaggcg gaggaagatc gcggccgaga gtagagtgac gcatccggca
  1330681 tagccatgac cgccgaaagt gaaacatgcg attggcactg ccagagcagt taggagaagg
  1330741 gcgccaacaa gccccagcag gaccgatacg cgcctcaacg cagtggccgt ccgcgcgatc
  1330801 gcgtccgcgt cgccgctgcc gacggctatg gcgatctggc gtacgccgct cgcctggatt
  1330861 ccaagcccgg cgagtgcgca ggcgatatcg gcgatggagc tgtagagacc catcagccct
  1330921 acgcccgcgg gaccgagcag caaagccgtc gccttgttgc ggaagatcgc aaataccacg
  1330981 ttgacggccg acgaaccgcc gatcagcgcc gtcgacttga ggatttgacc gtagctatga
  1331041 ccttcctcag gcctgggatg cgattgcatc gatcctactc gcctccagcc gccggacgcc
  1331101 tggcaacaga ttgtagccgc agatccggat caagaagccg ccgtacgacc agtttggtgc
  1331161 tgtcttgcca gggcggcagg caccagccga atattccctc gaacttgtcc gtgcaaaggc
  1331221 gcgagtcctg cgggcgccgc gctcttgtcg gataatcggc gcttgcgatg ccccgtatgg
  1331281 ttgcgaaggg gccgccgttc aggtggctga cggcgagaat atgtcgtgcg aaatccgacc
  1331341 aattggtccc gcccgtcccg gcgaggtggt agacaccaaa ggcatcgcct tttcggctcc
  1331401 tggcaatctc cagtatcgca gccgccaggt ccagcgccga tgtcggattg ccatgctggt
  1331461 cggaaacgac cgaaaggatc tcccgacttt tggcaagcct cagtatcgtt ctgacgaaat
  1331521 tcgtaccgaa gggactgtaa acccagcttg tcctgagaat gacgtggcgt ggcgtgatgc
  1331581 ttgcgaccgc tttctccccg tctagcttgg atgcgccgta taaggtgcgc ggcctcgtct
  1331641 gatcgttctc cttgcggggg ccgggatcgt caccagaaaa cacataatcg gtcgacagat
  1331701 ggattagggg tacaccgagc cttgccgccg cctctgcaac gcaggctgcg cctgccacgt
  1331761 tgaccgctct tgctcgggcg ggttcgtcct cggcacgatc gaccgccgta taggcggcgg
  1331821 ccgaaactac gacatcgggg ctagcggcaa cgatggcttc ccgaagcggg accggattta
  1331881 taaggtcgaa ctccggccgg ccgatggtga tgagttcgac atcgcctagc cttacggcga
  1331941 tctcggtgag gcaagtgaca acctggccgg tcgtaccggt cgcaagcact ttcatggcgc
  1332001 ggccaccgat ctgccgaggc gctcaccgcg atagttgcgg tcgcggatcg gctgccacca
  1332061 ccagccattt tccagatacc agtcgatcgt ccgctcgatg cccgtctcaa aactttccct
  1332121 cggtttcaac ccgagctcac gctcgatctt ggaggtgtcc atggcatagc gccagtcgtg
  1332181 acctggccgg tcgtccacga aagcaatgag gtcgcgatgg ctcttgccgt tgcggcgcgg
  1332241 ccgcttgccg tcgaggatat cgcaaatcgt gtccactacg tggaggttcg tgcgttcgca
  1332301 gcctccgcca atattgtagc tctcactgac agtccctttg agcgcaacca gatcgagcgc
  1332361 acgcgcatgg tcgtcgacat agagccagtc gcgaacattc gtaccgtttc cataaacggg
  1332421 cagcggcctt tcctccatcg cgttgaggat ggtcagcggt atcagcttct cggggaactg
  1332481 gaacgggccg taattgttcg agcagttggt gagaacgacc ggcagcccga aggtgtgatg
  1332541 ccaggcccgg acgaggtgat cggacgccgc tttagaggcg gaatagggcg aggaaggagc
  1332601 atagggagtg gattcgttga agctttcgtc gtcaagggaa agtgcgccga atacttcgtc
  1332661 ggtcgaaaca tgatggaagc ggaatgcctc cgccgccctt ccgcacagcc cacgccaata
  1332721 gtgcagggcg gcctggagca gccggaacgt tcccaggatg ttggtctcga taaatgcgcc
  1332781 gggaccgtcg atcgaccggt ccacatgcgt ttcggcggcc agatgcatga tgcgatcgat
  1332841 cttctctgca gacagaatgc tggcgatggc cccttcatcg cagatgtccg ctcggacaaa
  1332901 tctgtagttg cgaagattct cgatttgccg gagggaggcc agattgccgg catacgtgag
  1332961 cttgtcgagg ctgaccacgc gattgtcagg atcggcgacg aggtgccggc aaagtgcgga
  1333021 accaatgaag ccggcaccgc cggtcacgag gatgttcacc gacgcactct cccctcggcg
  1333081 acgccgaaca cctctgcctg ccgcagcagg ggagcggttc ggtccttgtc agacagttgc
  1333141 aattcggtgg aaggcaccgg ccaggcgatc gcgatatccg ggtcgtcgaa gcggatcgag
  1333201 cgatcgtggg cgggcgaata ggggctggtg accttgtaga tcacttccgt atcggcttcg
  1333261 agtgtcacaa aaccgtgggc gaaacccttg ggaatgagaa gctggttcca tttgcgggcg
  1333321 gaaatttcga ctcctaccca cttcgcgaag gtcggcgagc ctcggcgtat atcgaccgcg
  1333381 acgtcgaaca cggcgccttt caccaccctg accagtttgt tctgcataaa gggcggaagc
  1333441 tggtagtgaa gaccccgcag gacgcccttt gcggcggaat aggagtgatt gtcctgaacg
  1333501 aaggtgagcg cgagccccag ttcgccaaac cgcactgcgc tccaggtttc cgagaaaaac
  1333561 ccgcgttcgt cgcctattct ctgcggcaga atctccagaa cttcatctag gccaagcgct
  1333621 ctgacctccg ggctcatccg acatgctcct ccacgcgacg gcgtagatag taggcgtaag
  1333681 gggtgctccc gagcatgcgc gagcgcttca atacgtcttc cggcccaagc caacccattt
  1333741 ccagcgcaat ctcttccgga caggctatct ggacgccctg gcgacgttcg actgttcgaa
  1333801 cgaaggacga ggcatcgtgc aggctgtcgt aggtgccggt gtcgagccag gcgaagccac
  1333861 gaccgagttg acagacatgg agcctgtcgc gctcgagata gatgttgttg accgtggtga
  1333921 tctcgagctc gccacgcgcc gagggctgga tcgaagcggc aatgtccacg acttcattgt
  1333981 cgtagaaata gaggccggtc actgcccagt tggatttcgg ccgtagcggc ttctcttcga
  1334041 tcgatttcgc ctggcctgtc cgctggtcga aggtgaccac cccgtaacgc tccggatcat
  1334101 cgacgcgata ggcgaacacg caggcgccgc tctcccggga ggcggcctgg cggcagacat
  1334161 tcggtaggcc gttgccgaag aagatattgt cgccgaggat cattgcgaca ttgccgcttc
  1334221 cgatgaaact gcgtccgatg ataaatgctt cggccagccc gttggggtga ggctgttcgg
  1334281 cataggacag ggtcaggccg aaggccgagc cgtcaccaag aagggcttcg aagcagggca
  1334341 ggtcgcgcgc cgtcgagata atgagaatgt cgcggatacc ggctagcatg agcacgctca
  1334401 acggatagta gaccatcggt ttgtcataaa ccggcaggat ctgcttcgaa atggcgatgg
  1334461 tgagcgggta cagccgagtg ccgttgcctc ccgcaagtat gatccccctc attttgcctc
  1334521 cccttcaatc atgctggcca ggcgaacgcc gcctgccgag gcttccgtca ctggctgacc
  1334581 cgatccggtt gtgagctggt cgaaagaggc gagctcagcg gacccgcgga tatagcggga
  1334641 tcctggcgcg cgggccggac gatccgaatg acatctcccg gcctgagcat ggtcgaaccg
  1334701 gacgccctga cctcgtcggt cttctcatcg ccccgacgga tgatcttgaa acttggcgac
  1334761 gcctcttcgc caggcggagg cgagttatcg tctgcagcaa gcatgtcgag cagttgcttc
  1334821 tccgtggtga cccgcttcaa cttcagttgt tcgagcgcgg cctgctccgc ctgcagttcg
  1334881 ctggcgactt ccgcgtggcg gttgtcgtaa agtccctcga gactgcgtgt cgttccgctg
  1334941 atttcctgtc gggcgcgcat aatggcggtg atgaaatcga gacgactggc gtgatagccg
  1335001 gcaagttcgc gctcgagatc cgactggcgc gatgcgacgg cgacgccgcg ctccaccagg
  1335061 ctcctcacac ctttgagctc ctggtcggca gctcttatgc tggcgtccga gccattgact
  1335121 ttctcttcga ggacgcggat ttcctggtcg aggagattgc gcagttcgtc aagcgatttc
  1335181 gattggcgcg tgagcacgtt cgcacgcgtc gaaaagataa tgcgctcctg gttctggatc
  1335241 tccgtcacat gcgatgcatc ggcccctatg ggctcgggaa aatgtacttc cttcactccc
  1335301 gacacttccg cctgcaacct tgctattctg gcattgctgc gcaggagagc gagatcgacg
  1335361 ctcttcagat cgccgatcag cttcatcctg tcttgcgatt gcgtggggtt tgcctgacgg
  1335421 agctctccgc cgctcatggc cagggcctgc aaagcggtca gtccggggcg aaactcatat
  1335481 tttcccggct ttgtcacgtc acccaggacg tagaccggcg gatactcgac gacttcgatg
  1335541 cttgcttccg gtgcttccat caagccgagt ttggcttgca gccgcctggc gatctcggcg
  1335601 gcaaggcgcg cctcgtcgag gtctcccacg gtaaccgccc caatgacggg tatcgtgacg
  1335661 gtccccccct ccgatacgac aaaatcgccc ccaagcgccc attggatata ttcacccttg
  1335721 gtgggcatcc actgcatgat cttcaggcgg attttcgttt cgggcgcaat cgcggcagcc
  1335781 gcggccatat tgggcgtcaa tgctccattc aaaagtgcca gcgcagctac gaaggtactg
  1335841 cgaagaagcg gagcgtgatg ggacgcattc atgtatttct cccagcctct gtcaaacgga
  1335901 gaagacattt ttgcctcggc aacatcatcg ccgccaaaac catgcccgcg cgggaagccg
  1335961 aagcggcaag tgaaagtgtg ccagcttccc cggcgttgaa aaggggaact gcagcggttc
  1336021 ggcttcatca ttatggttga ggtcttcggt cgcgtgttcc gtcaggaagt tccaaccgat
  1336081 ggaaagaaat atcctgaccc gacattcgga tgatccggga atggcaaatg atgaagtgaa
  1336141 tgggtgaccg taatcgatag gtggagggcg atggcgcgtc ggactagttc gttcggataa
  1336201 atgccatcag aagcgccgtc tgctcctggt tacccgtctt ggcatttctc aaccgttttg
  1336261 cgccgtcgcg acccgccgcc gtttaggcta gagttgcccc acggcaggaa tctgtcgatc
  1336321 gaaaattccg cggggagggt tatcccttaa tgaacaggag agaccacgac gaagcgcatg
  1336381 ccgatagcgc tacgcagacc gcgaagctgc gagagccgcg ccgcattata ctgatgataa
  1336441 ccgatttcgg gacagtctcg gagaggctga tccatgcact ggagcgggag ttcccctggg
  1336501 tcgtcatcga gcaggtcgag catgttgccg cagcatgcaa ggtctttttc catcccgtgt
  1336561 cgctgatcct cgtcggcccg cgattgctgg acgaagccga agcaagggcg gccgaactcc
  1336621 tgcggctgca cccccaagct ctggctgccg tgattgagct aagcgatgac gatctgctgt
  1336681 tgtcctcggc caatgtttcg cgatcgccac tggtccggag cctgctgccg atgaacctcc
  1336741 ggttggacgt ttggttgtcg gtggtcaggc tgatgctctg cggcggcgag taccttccgc
  1336801 cagcgcttat tctgcggtcg aggcagaacg gtcacagcgc tgtcccgccg ctggaaaacg
  1336861 gcgcaagagc gaccctcgtg gcaagtgccg atccgaggat ggccggattg acggcgcggg
  1336921 aactgcagat tctcgaaatg gtttcgcgag gtctgcaaaa caagataatt gccgctgaaa
  1336981 ttcgcctgtc cgaaaacacc gtgaagatcc acctgcacaa catcatcacg aagctcggcg
  1337041 cccacaacag gaccgaagcg gccgcgaggt ttcgaagctt gcaagagcgc cactgatctc
  1337101 acccgtatga tcgatgcatt tcgccgggcc ggcgtctttt cggcagtgcg ttccaatact
  1337161 gccggagaaa gtgggggagc ggttccgccg gaatatgcgt ggcctcaaag agccagctcg
  1337221 gcggagcgtg tcactacgcg tatatagacg tcctcaaggg gtgaacgtgg ccggacgagc
  1337281 tgacgcgttg caagtcgcat aagcgcattc agatgctccc tgccgccata gccgaccgtt
  1337341 ttggcgaacg gcttcatcga ggagtgctcg ccagcgggat aaagtcgcgc gtattccgcg
  1337401 ccgttcgtga actcctcata attggagcct tccacgagga aagtctcgac aggggcaccc
  1337461 tcggccaata ccgcttcatg tgtggcgagc acgatgtggt agaattcgag cacatccaac
  1337521 ttgccaggca gcgccggtgc aacagacgtt ccgttgatga gatcctttgg tctgataaag
  1337581 acgccgtcga catagagcgc gtgaccggac gagaggtaga ggtctttgcg cggcgtttgt
  1337641 ttgtcgaggg cgaaacggcg gatgcggatc ggcaccacgc tatcgttcca cgtgggtgac
  1337701 gtacgccgat agacgtggcg acccatccat atgaccggca gtaattcgcc gcggaccgtc
  1337761 ttaacaagat cgcccatgcg gagatcttcg atcaccgtct cgcccttgga tgtgaggatt
  1337821 gccgtgccgc gtagcaggca catgggaggg cccttgccca caccgccttg gccaggaccg
  1337881 cggcccggat gttttgaggc gccttttgcc gatcccggtg atgcgatagt ggcacccaat
  1337941 gcggcgatcc tggcgcttgc agcggcggcc aagccgatga agtggcgccg ggcctgatcc
  1338001 acgggcggcc tgctttctct cggaggcata attgccgtcc tctcgttcga gtgtcctccc
  1338061 attatagatc tggcgcgttc gggttgggat atcccaattg gaccatcgcg ctgccccaaa
  1338121 ggggggaggt gcactgtact tttggaggac aggcgtctgc acgacccgta aggtctgcgg
  1338181 ttccgtctgc cgtagggcgc atgcttatat atttgccgcg tatagatgtc taaaggcagg
  1338241 atagtctggc cgggcacgct cgaagcgccc ctgtcgatgg cgccgaccat cagggtctgt
  1338301 cgttttctgg gccaaggccg gaacgggcgt cgagatcgcc atcaacactg tttcgacgct
  1338361 cgatctcttg cagcgccatc cggatctctt aggcttttac gtctgcggcg gcggcatgga
  1338421 gggcgccatc tcggtgatcc gcgaggaaaa gctcggaggc aagctgctcg ccgtcgtcaa
  1338481 cgagctaacg ccggaatcgc gcgatgccct tgccgacgct gccacggtga tgccgccgca
  1338541 ccagcaagga gtggagacca aaccggcctt gcgtggacca acacgctcga gccatccacc
  1338601 ccaaagcgcc gctgacgatc cgagaagcac gaagaacagc gtgtagaaac agccgagatc
  1338661 ggcaacgcgc cagtcccagc tggtggtgaa cagtgcgcca agcagattga ggtccgaaca
  1338721 ggctgccggc tgattgatgc cgatcgatcg cgacagcggg agccaaaaca cgctgaagcc
  1338781 ataggccatg cgaatacaca ggtgactggc aagagctgcc ggtggaacca gtcagcgatt
  1338841 gaagccgggc tgagcaatga tccgctctcg gtcgagaatg ctgcccccat aggcaccgga
  1338901 taaagtgtct gtctataatc gtcataaggt ctcctccgct tcgatcccga tcggatctcg
  1338961 attttgctgg aggagaagcc gataacgaaa gctatggcaa gcgggtcggc atgctctagc
  1339021 gtcgccgtgc cctagctgcc ttccgggagg cttgcctcgc gatagacgag atcgttgatc
  1339081 gtgccgatga agagaagatt ttgattgagc agcgtcccgc cgaccagaat ggcgcgactt
  1339141 ccatcagcga gcgaaacaga gctcgcgctc cgcaccacca tgccacgtgt tcctcgctct
  1339201 tgtccgtcgg catggcgttg ggagttgcca cgagcgccag ccgggctctc tcggcaaaag
  1339261 caggtgacag gcgctgcaga tcctctggac tgaggatgtc gatcgctgtc gcgggccgac
  1339321 catggatggc ggcgcggatg atcggccagt cgatgcgtag ctgcgctccg gcttctgcgg
  1339381 agctggaagc ctgcaggttt ccatccgggc tgacaatata caggaagtcg agatcgagct
  1339441 ttttcctgct gtcgccgagc aattgcacga gcgccgggcg gccctcggcg acgacatcgc
  1339501 gaaagcgcgc cgacccgcct agcgcgatga tgtgcaatcc ggtgttatcg aggatacggg
  1339561 caagaaactg atgggcaatc gtcaggtcgc cgttgacctt ggagatcagg gcggcgtcga
  1339621 acttggcgtc ccagcggcag atcgttacgt ccagcaacag cggcaggatg actaacattg
  1339681 gcagaagggc aatggcgagc agccggtatc gcagggaacg ggcaggggga ccagcaccgc
  1339741 gatcgtcagg ttcaggcagc ccagctcgcc aagttgcggt cgatcgtctt gcgggaaatc
  1339801 ccaaggcgca gcgccgcctc gtcgcgctgg cctgagcacg aggccaggac gttcaatatg
  1339861 tgttggcgtt cgacgtctgc gagtgtcacg tccccggcat tttccagctt gccagtcgaa
  1339921 aaggcgaact cttccgggaa gcggccgagg ataagggtcc gctcgatcat atttcgcaat
  1339981 tcgcgcacat tgcctggcca gctataggca aggagcgcct tgcgcgtttc ggcgctgatc
  1340041 ggcactggcg gcacaccgag ttgccgcgca agttttgcca tgaaaagttc ggcgagctcg
  1340101 agcgtatcgt tctcgcgctc cttcagtggc ggcaggtgaa tctccatgac attgatgcga
  1340161 aagaagatat cggcgcgaaa acggccgtcc tggacggcct tttcgagctc ggcattgggt
  1340221 cgcaaagacg aaacgcagat cgaccggaag ctcgcgctcg gaaccgatgg gccgcacttt
  1340281 ccggtcttcg aggacgcgca gcagtttagt ctgcgtcgcc gcgggcaact cgccgatttc
  1340341 gtcgaggaag agcgtgccgc catgagcatg gaggaacagt ccctctcaat cgcgggacgc
  1340401 cccggtgaat gcgcatttca agtggccgaa agctcgctct ctatcatatc cggcggaatg
  1340461 gcaccgcagt tgaccggcac gaacggtttg gcggcgcgat cagaaaccgc gtgtagcgag
  1340521 cgcgcggcaa cttccttgcc cgtgccggat tggccggtca gcagcaccga agtgggtagc
  1340581 ggtgccaccc ttgctatcgt ttcccggaca cgggcgatcg cggacgattt accgatcagg
  1340641 cggtcgcgaa gcagcatatg gtcggacgct gcccttaact cgtaacgcta gttctctcaa
  1340701 ggaggagcgc tgtactgatt tcgcattagc tcggattagc aatcttacgt tgtgacccac
  1340761 tccgtatatt atcaagttta aagaaagggg gtgccctgca aatgacagtt gcgtctgaag
  1340821 cgtttgctcg ggtattggaa acctcgatac tgcgtcttgc gctcgacgac agcgataaat
  1340881 cccacctcgg atctctcggc ttcattccaa ggcgttaccc cgcgcatgcc gtgattaccc
  1340941 ggcagggaga cgaggaggat cgcatcttcg tcgtccattc cggttggggc tgcatctgca
  1341001 ccaatctgat caatggcgag cggcagatcc tcgatttccc gctgaaagga gaggttgtag
  1341061 cctctcgagc cttcgagggc gaaggtttgg aatcattcac ggcacacacc gaggtcatgc
  1341121 tattcgaggc gcccgccaag tcgatctcgg caggcctcgc ccattccacg agccttgccg
  1341181 ctggcctgct cggggcgatc gcccgcgaaa aagcgattct ttctcagcac ttgacaaatc
  1341241 ttggccgaag aagtgccttg gtccgtaccg cccattttct cctcgagctg ggtacgcgcc
  1341301 tggagaaggc ggaggctgca aaaagccatg ggtttgaatg ccccctaacc caatatgatc
  1341361 ttgcggccgc actcgggata accgcgattc atgtcaaccg gatgctgcgc gaattgagac
  1341421 agcggcgcta cgtggatttc cgccagggtt ccgttcgttt gctgaacaaa gaaggcctcg
  1341481 agcatttcgc agattttgat ccaggttacc tccgtttgcc cggcgagaca tgaaatgcga
  1341541 gtgcgagatg gaagggttga gcgtgagcgc tacgaacagt ccatcttcct ttgctgattg
  1341601 agagcgcgag ataagctccg tcatcgacag gagtggaacc ggatggttgg agaccgcgct
  1341661 ggcgccatgc ttggagtcat ggatgaagcc aggcacgagc ctgccggcgg atcgaagtga
  1341721 tcaccgggcg acgccagcgg cgaaattgga ccgacgagga gaaggcgcgg atccttgcgg
  1341781 agagcgctga acccggagtg aacatctcgg ctgttgcctg gcgttcgggc gtcaatcgcg
  1341841 gcttgctgaa tgtctggcgc cgcgaagccg ggctgacctc tcgacgatcc gagcaagcct
  1341901 gcgcacagca ggcgatgttc gtgccggtga cagtggttgc agaacgaacg cttcaccaga
  1341961 gcgcgtcgtc ggttatcgct tccgtcgctt ccgttcgatg aaatccctgg ccctgacgag
  1342021 gaagagttcc ttgttcgtgg gcagtgcgcg cggcggagag actttcgctg tgctcgcatc
  1342081 actggtcaac acggcaaagc ctaacggcgt ggatcctgaa gtctggcttg ccgatgtgcg
  1342141 ggaacgcatc atctccggca aagtgaaggc caaccggatg gaaagcctct tgccgtgggc
  1342201 ttggaaggcc gaacgcgagg gcattacaga tcaggagcga cgggcggcat gacacagaac
  1342261 cccaagagga cgacggcacg accggactga ctgtccggag gccctgaacc tgccgatgga
  1342321 aacgaccgag catcgggccg tacagaccat cgttgcggaa tataacccca tctcggcgag
  1342381 cctcgccgaa acgccgaaag accaccggcc caggttcacc aggatcgatg atcagacctt
  1342441 taatgccatg gacctgggac gtctgctttc tgatgggaac cgggttcgcg ccgaagctgt
  1342501 ggcggcccgt cattcgcggc catgccgcca ccggcgacat catcgcgcca atccgcaagg
  1342561 tcagcgagac aaaaggacca gctacccata aggatgctgc tgccgtcgcc gaggcgctcg
  1342621 tcaatattcg aagctacttc atgccaaggc gcaagcagaa gttctaaaac agcggacggc
  1342681 tcctcctgcg tcaacagacg aaggccgtgg gatgctcgtc gcgctcacgg ttgagcctaa
  1342741 ctcaaaatgg ttgcagtgtg agccactcga aatagagtaa cctacaattg ctccgttttg
  1342801 attacatttc ctatctcgag gcgaaataat gtcgcgtatt aacgtatgtt aatgaacgtt
  1342861 cgcggtcaaa agcctattct cgttttctat tggggattgg cgctttacag gcgccctttc
  1342921 aaaaatgaca ttttttaagt ggcggttgac gtgaaccgtt cagccgcacc tgctcaccta
  1342981 tttgcgcccg actaatgttg cggtgggggt gtaccatgca ttcattgact cgaattcacg
  1343041 aaaatgccgc gctcgaagta cataggctga gctcatccgg tcctggtaag gcaactagtg
  1343101 aaacgcataa caacacggca gcaagctcgg ctctgctcct gttggacaac cgaacgctcg
  1343161 atagggaatg cctctcccag tgtctcgtgc tgcatggtat gggcatgcaa gtcttagcct
  1343221 atggttcaat tgatgaatgg cggaaggata aagaacttca tccgcccatc gcggcaatcc
  1343281 tgttgaacat cggtggtcga aaggctgtcg ataccagcaa tgcggccgaa atctcggatc
  1343341 tggtaaggga atttgacccg acccccgtcg ttctcctatc cgattgggat gaactgcctc
  1343401 aaatcctcag ggcactcgag tgtggggtca ggggctatat accatcctcg atcggctttg
  1343461 acgtctgtgt gcaagccgtc aatctggcgc gagccggcgg gatattcgtc cccgccagca
  1343521 gcgtcctgac cacacgaatt gacattgtcg ctggcgggga ggtgtcacgg cccatgacag
  1343581 ggatgttcac gcagcgccag gaagaagtca tccaagcgct gaggcgcggc aaggcgaaca
  1343641 agatcattgc ctacgagctc aatctgcgtg agagcacggt aaaagtccac atccggaaca
  1343701 tcatgaaaaa gctgaaggct acgaaccgga ctgaggtcgc ttacaagctc agcgatatgt
  1343761 tcgtcgccga gggcggagca cgggacaagc cgggactgcc gcaatcagga tcctgttaat
  1343821 ggttccaaca attggcggtt cgcaaggcgc ctccggcagt tcgagatcgt ctcttgctct
  1343881 tggtcggctt ctcgctcgaa catgagacac cgtcttcgtc tgcgacttgc tgaatgttcg
  1343941 cttgtccaga ttgccgcagc ctcaagcctg cggcgggacc cggcccgtgt agtgcgcagg
  1344001 ttagtccttg ccggcaccct ccgtcttttt ctcccggttt gtggacgggt cgcttcgtgc
  1344061 cgaaggagca tcggcgtctc tggtaccggg ttcgtccgct tggtccggca gcggaacggg
  1344121 ttcgaaatcc acctccggtg gtactgccgt ccgccgggat gacgtttgct gttcggcgag
  1344181 tttgccgtca ctcattgccg tattcccgta ttcctttcga gtcgcgatct gaaccaaccg
  1344241 caatcggtaa ggttccacgc caacggggag agcgtttgat ggcctaccga atcgtcaacg
  1344301 ccaaccaccc cgatccgatg ctcaagcgga agccccgaag agcaaggata atctggcatt
  1344361 cagcgcgtca gcgtagagcg gcccggtcgc tcgccgccat cgctacgcct cctaatgcaa
  1344421 ctttgttgca aaacttcagt atttatttgc cgggcttggc cttacctttc gcgttgtttc
  1344481 cgcccttacc gcccttcgtt ccatttccac ccttgccgcc ctttgcgcta ttcccgcccc
  1344541 tgccgccctt tccgacgttc gagccgccgc cggatgccgc gatggcagca gaggtgaggc
  1344601 tggttgaaag caacatggtg acagcaggtg gcgtgattgc cgcgaagcgg ccacaagctt
  1344661 ttgaaacctc gcgtctgtct tcctcggcgg gtgaatttac tttccgatgc tcttccaatg
  1344721 ctcatcctcc agttggatgc gctagttcta cagaaatttc taatgatctt ggatataatt
  1344781 ctctatacgg gtcagatcgc taatacttcg acgacatctg caccagctgc ctcttctcag
  1344841 agctactcgg aggcgttgct ttgattagag tgaaagttcg aagtgtaaac cgcgacaccc
  1344901 ctgctttccc ggttcgacag ggcgtctccg atcatcagat aagctgcaat cgtcaacact
  1344961 gataaaagca caatgctcaa ggggaggccg gtggatgctc tctgttccgg cagtccaaaa
  1345021 tcgtctctgt cgcgcatcaa ccaagtcctc tttgacacca cgtccgcaag gcactgtcgt
  1345081 cagccgagag agcctcagcg ctgcctagaa gggacaatgc aaggcagcgc tgaggaactc
  1345141 actcacacga gcggctgacg agggggccgc tcgggggtga caactccaat ttgcgtcgat
  1345201 ggtttccgtc tgcgacctgc taggaccttt gcgcccatga ggctcagacc aaagtccgag
  1345261 agatgactaa cccaaatgaa ctgggaaccg caggatccct ccagcgttcc gtgctattca
  1345321 atgcgcgagg ggcgaatatg gaagcggtca cgatactgct cgccgacgac gaagcgatat
  1345381 tgctcttgga tttcgaaagt acgctcaccg acgccggatt tctcgtcacc gcggtatcga
  1345441 gtggagcgaa agcgatcgag ttattgaagt ctggggccgc aatcgatggc gtggtcacgg
  1345501 acatacgctt ttgccaacct cctgacggct ggcaagtcgc gcgtgtggct cgcgaaattg
  1345561 atccgaacat gccgatcgtc tacatcagcg ggcacgctgc cctcgaatgg gcgtcaaacg
  1345621 gggttccaga cagcataata ctcgaaaagc cgtttacgtc agctcaactt ataacggctg
  1345681 tttcccagct gctcaacgct agaccacctc gcgctcctcc gagtgatgcc taatcggaga
  1345741 gaggagcgaa ttggtcaacc tccggctgcg acgtgttggc tggcacgttc cggaacaatc
  1345801 ctcgtttttg agagcggcaa tttcaggccg gctccggtag cggctgctgg ggaaggggac
  1345861 tgtctccact gccatcatcg tcatccgccc accgccctga tcagccaccg ccaaaagcct
  1345921 cttttggcgc actctcccgg cgtgagcttc ccacaccggc aacggcactc gcctgaataa
  1345981 gctggtcaca tatatcgtga cctatattgc cggcctttct ctctgccgta ttctagtcgc
  1346041 gcaacctggt gccgatttca caatcgaggc gatgaatgtc gctcggtggg tgatccaccg
  1346101 gccgaaggtc gcacctttgt caaccggtta tgtgagggta aagcaatgaa acggcttatc
  1346161 gctgtatcgc ttcttggggt ggcatacttg gttgcaacgc cgcttatggc aatcaccgtc
  1346221 tttgaagatg gtggcaaggc ttacgcggat agccgcgacg tcgggcacaa aaaaggtgac
  1346281 aaacagggca actgaaagcg ctgttcctag gtgattcctg aaataaagac cgcccgcgcc
  1346341 gggtgacctg cgcgggcact acgaaacagg ttggggacct tgttccgctt tccaaatttc
  1346401 aagctttcaa gcttgtcgcg gcttccattc gggccggtgc tcgaagcaga accagtcagg
  1346461 gtcgccgcgg ccgacggcga aaccaaagcc accccatttg gtgcagccag gatgctcgca
  1346521 gtaattgaca taagggccag cctcgtagtg gggcttcgcg ccctgtttgt cactcatctg
  1346581 cttgatcctt ctccccggcc ggcgccaaat tgctgctcga atgcctgttc ccaattcggg
  1346641 tggcaggagg cgctgacgtg cttcaggggc tcgaaatggt atcgcgcgag cagggcggcc
  1346701 gagattatcc gcgccatttc cttgcgggcg ccttctgctt tcagccgatc gcgatcgcag
  1346761 gcggctcgcc gcaattcaag ggggatcgcg tagagcgtct gcgtaacgaa tggagcgatc
  1346821 gccggagacc gcagcaccgt ctcgacatcg aagatggcaa acgctccgaa ggattcggca
  1346881 attcccttgg cgagttcctg gacgccgcgc acctctacgg gacggcgata ctggtcgagg
  1346941 ccggcatagg cccgcctttg gtgcggcggc attaccgcaa gatcgacttc aatcgcggtt
  1347001 cctatctcat cggcaagtgt tcgcatgacg cgcgtctttc tcgttttcgc tcctgattga
  1347061 tggaatggcg ccgcatcgcc gtcgaatgtt cctaatatgt tctctcagcc gaaagagtca
  1347121 attcggcttt tcgcgggcct gtgctaatgg tcagagcatc ctcgaagaag ccccgcgacg
  1347181 ttgccccgaa tgatcccatg ccggcgcgca tcgatccctg ccttgccact ctcgtggaca
  1347241 agccccccat cggccccgac tgggcctatg aggtaaagtg ggacgtgtgt ggataccggc
  1347301 tggcagtgca catcgagcct ggccgggtgc gggttctcac gcgcggcggc tacgattgga
  1347361 ccgatcgctt tccgtcgatc gccgatgacg cgcggcgcct tgccgtcaag acagccattc
  1347421 tcgacgggga ggcggttgtt ctgaacgatc agggccgctc ggatttcggc atgctgcaac
  1347481 gggctctcgg gcgcttgtcg tcagcagtcg aagccggtgc gatcgtcttc tatgcctttg
  1347541 acgttcttta cctcgatggc cgcgacgtgc gccgtttgcc gctgcgcgag cgtcggcggc
  1347601 tgcttgagcc gctcgtcgca ggccgggaag gggccgttcg cctgtcggaa gaagttcagg
  1347661 ctgatggcga cgcgttcttc agcgtcgcgt gcgcacatgg gctcgaaggc attatcgcca
  1347721 agcacgtcga gaagccttat agctccggcc gcggcgagtg gtggcagaag atcacttgca
  1347781 aacgccggga tagctttgtt atcgtaggct ttgagccgtc caccgtgcct ggccacctgg
  1347841 gccggcttct gctcgccgct cgcaagaatg acgacctggt ctacctcggg gctgcggcac
  1347901 gggctggtcg cacgatctat cacgcgagct gcgcaacgtc ctcgcatcgg tcgttgcgaa
  1347961 aaaaccggca gtgagccttc ggcggaagaa tgctgtcttc accgagccgg tgctcgttgc
  1348021 agacgttgaa tatcgcgcct ggaccgacga tggaaagctg cgacatgcgt cgttcaaggg
  1348081 gatcagggag cgggacgatg atgtggagat ttattctctg gaacattagt ggtgaattcc
  1348141 ggccgcagcg agtttacgcc agacgttggt tctcgaaagc tgccggttga ctttcgacaa
  1348201 gcgcttcgct acctgtggtg gctaataccc ataaaattta ccagtaattt tttatcggaa
  1348261 agggcgctcg atgatcagaa gcgtcgttga gattattgcc gcgattttta tcaattcggt
  1348321 tggagtggcg ctggctgcta tcgggatcga gtcagtggac tatggtagtt tttttcaatt
  1348381 gcttctcgtt atatctgctg ccattgtttt gagcgcaatg gccgtctggg ccgctttgcg
  1348441 cattttcgat caagactatc catatcgcct tggctgatct gcgcgccgct ttgtttttcg
  1348501 gttcgcgcct ggaccgagga tggaaagctg cgaaatgcgc gttcaaacgg atcagggctc
  1348561 tggcggatga ttttaccgta tttgcgctac catagcgagg cgaaccgccg ttcctctacg
  1348621 caatcatata taaaactata tatatcaagc gccaacctat ggtggcacac tccgtgcgtc
  1348681 atcgataagt gggggaagcg ttcatgcccg aaataccaaa tgaagtgccg tcaaagagcg
  1348741 acgatgatcg gcgggaattt ctgaaaagtt gtggtcgctt tgcgattgta acacctccgg
  1348801 ccgtaacaat gctgctctca accagcctaa cgtcaaatgc aatcgccaag tctggcggcg
  1348861 gcggaggcgg cgggaaagtt aaaggcaaca acggctgggg taacggccca gatccaacga
  1348921 acccaggcag ctcccatggc ggtggcgttt cacagggcgg tcccggcgcg ggcaattcgc
  1348981 aaagcggcac caagaccggc ggagctcgtt agctcagtct ctatgccgct tcggaaaaaa
  1349041 cggccgtcaa cggactgagc cgtcgacggc acgaagtcgc agcattgtcg gctgctactc
  1349101 ccccgtttgt gggtttcttg cctcttcgcc aggcgctcgt tcttcattct tggaggccgg
  1349161 cgcttacgct ccgtcttgcg gcccgcccaa ccaatccttt gtacctgccg tcttcgcctg
  1349221 atcaccggtt ccggtgggcg ctacggtggt ctgcccgttt tgttgataac cggctccggt
  1349281 ctcgccgcta cgctgctcat tccatttaag ctggccccga agattttctt gagattctgc
  1349341 ctcgggtggt tttcccctgc cagaccagct ggaagacgtg ccatcgccgg aggcgatccc
  1349401 gtattcgggt gggtcttcga ttgtcttctt ggcaggaggg gtcttagagt tatcggtcat
  1349461 gacgatctcc actgttgcgc gttgttggat ttttgtcggg cgaacccggg ttctctgttg
  1349521 aaccgtcgtc aggtcgtaca gaagggtgcg gcgtgatcgt ctcctgcatg attagttcac
  1349581 cgaacctgac attcctttca gtcacgctca ggaacgtcat gaagctatca ggctgttcgg
  1349641 tcaaaactac cctacgtttt aatgatacgc gctattctac tatcgcaagt tgtaattgga
  1349701 aacccgacac cagcgtggaa tttgtagggt cggagcgatc gcatccatcg ttcaagggcg
  1349761 tcagggagcg gccgacgaag cgaccaaaca tcaccttggt tgatgcgttg gagggcggct
  1349821 atccggcatt gaacacctca gcccgaacta gatctttgtt gacgcgttaa ggagagcacc
  1349881 gatttgcggg agacctgaca gtgaaccaaa ttctttttcg aatggctgat ttcctttctc
  1349941 ggccgccagg cttctatttc atgatcgtgg cgatgattgt cagcaccgcc ttggtgcctt
  1350001 tcggtctgac aaacgtgatc acatatgctc tgtcagtcgc tgcaatagtg atcaccagcg
  1350061 tcgttttaat ccaaggctat cgagacacgg cggcaattca cgccaagctc gatgaaatca
  1350121 tcgtctcgat gcgtgaaact cggaacgagg tggtcggcct agagcacgaa caaccagagc
  1350181 gcatcgccgc ggcagtcgag cgtctcgaag cggaagctgc gggtcaagcc agagctggaa
  1350241 tatcgcacct cgaccgatga tggaaagctg cggaacgctt ccttcaaagg cataaggccg
  1350301 aaagatgatg acgcgagggt gttcgagccg acctagcctg aaaaccccaa atgcaaatcc
  1350361 gagtgaccgc gtcccgaaat aaatcccgaa ctgaccttct ggacatgcaa tattagggct
  1350421 tccagcaaat tagccctctc tcctgggggc aagtggtaga ttccaagacg ggaagctccg
  1350481 gcttgcatcg ttcaggggca tcagggagcg ggaagacgag gctcccattt acgagctacg
  1350541 gccgcactgc ctctgctgag ctattcgcta ccggtctcct gaactggcgc aacgtgaaat
  1350601 atcccgcgac gccactgata accggcgtga tcgcgccaaa ataagtccaa ggtctcgctg
  1350661 cttccccagc accgtcaaag taggtgacta tttcgatagc ggcagcagtg gtcagcacgg
  1350721 ccagcgccaa ttccagcaag taaacctctg taagaccgcg aacctcgccc agaaaccgtt
  1350781 ggggagcaaa tgtagcgaca acgatggcag cgaaggtcgc ccttacccat ggcgcgatcg
  1350841 gaagttcgcc tactggtatt tcgtggtggt aggcgacttc agagagttgc aaccatgcca
  1350901 agcccggcgc ccagggtcag tgcgataagg ttcaatgcga atgccttggc ccagttcatt
  1350961 tccgctccat ggatgcgcga tggcgactgg atgaccgcgg ttcttccacc cgcaaaatcg
  1351021 ttcggtaaca ttcttcggtg aggcaatagg ggggggcagt ttttcatttc gcccgacacc
  1351081 gacgctttga tggcttttgc ccatgtcggc gcgcccctta tggtcgatag cttcgccggc
  1351141 ggtggtggag cctcgatcgg catcgagatt gcgctcggcc gctcgccgga cctcgccatc
  1351201 aaccacgatc ctgatgcgct ggcgctgcac gcggcaagcc atccagagac gcatcacctc
  1351261 tctgagaacg tctatcgggt cgatccgctt gatcatctga agggcaagca catcggcctc
  1351321 gcctggttct ctcctcgagc gcatccagaa gagcggcgac cgcgtcgatg tcgtcatcat
  1351381 ggagaacgtc gaggagttca aggatcatgg gccgctggtc gcgaccgatc gcgggctgat
  1351441 gccgtaccct gagcgccgcg gccagaattt cgagaaatgg tgcaagagct gcggcggttc
  1351501 ggcggcaaag tcgagtttca cgagatgcgc gccggcgact atggcgctcc gacgatccgc
  1351561 aagcggctgt tcgtaatcat ccggttcgac ggcaagccga ttgtctggcc cgaacccacg
  1351621 cacggtaagc tgaggacccg gatgtgatct ccggcaacaa gctgccgtgg cgtaccgcag
  1351681 ctgaatgcat tgactgttcc ctgccttgcc cgtcgatctt cgcaagctcg gccgagatct
  1351741 gggccgaaca ccaactccgc gccgtccggc cgctggcgga cgccacgatg gcgcgcgtgg
  1351801 cacgcggcat gaagcgctat gtgctcgagg cggagcgacc tttcatgtca atctgacgca
  1351861 cggggacgaa ccgaggatct caacaagcgt tcaacgtcat cacccgtggc gcatcgaggg
  1351921 gaggaggcgg tggtgacgcc ctatgtcgcc tcctactata gccatactaa tggtcgctcg
  1351981 gagcgcaggt cgaacctcgg cgaacgaatc gcgaccatcc caacggagaa ccgtcacgcg
  1352041 cttatcgctc cggtgctgac ggcggcgcaa cagggcggtt ccgttcgccg ggtcgatgct
  1352101 ccacatcaca cgatcaccgc cagcaacaag gatcagaact cagatatcgt gccgaggctc
  1352161 gtgggctgcg gcggacgggc agggcaaagc cgacctcgcg gcggtgacga accgacggga
  1352221 acgatcacgg ccaaggcgga tggctgcgtt gcggtcgcct tccttgcgca aaacaactat
  1352281 cttgagcctg gccatgatgc gcgcgaacca ctgtcgacaa tcgtcggcag ggtcagcacg
  1352341 cagagcccaa tagttgcttt catagcccag cacaatggtg attcgcgccc cgatggtagc
  1352401 gaggccgctc ggcccgggcg tgattcgggc gaaccattag ccaccatgac acaatccgga
  1352461 agccagcaga gcctcgtctc cgcatttgtg gctcgccaat tcggcaactc aaccggccat
  1352521 gcggacgacg aaccaaccgc caccgttatg gcgggcggtg atggcaagtc gcagctcgtc
  1352581 acaccatacc tgcaggcata ctacggaaca ggcgacggtc aggtcgagag cgagccgatg
  1352641 cggactgtta ccacgaagaa ccgccaccgc catgtcgaag cgactatcag tgctccaccg
  1352701 ttaaccgaag cgcaggccga gcgcgcactg caagttgccg aattcatgcg cgtctccctc
  1352761 cgcaacgtgc cggttcacgg gctgcgccgt gcctacgtga agctgaagcg cggcgaatac
  1352821 gagaacatca acaaggcatt cattcccctc ccggccgagc ttgcagccat ggccaatgct
  1352881 gaatgccgtc tcatccgcga ggaccgcatt cgcaagcagg aaaggctgag ggcgatcgag
  1352941 gactcggtca gccgaacgct tcccagctca catgggctca tggacctgcg cgtcacccaa
  1353001 cgtgagcgcg ccatcgagtt ggcggaaaag ggttttgtca gggtggccga aggtgttgac
  1353061 catctggaat tcgcccacct cgccaaatcg cgggaactgc cggccggttc tcgccatctc
  1353121 tggtcaccga tcgccgtccg catcaaccgc agcaggatcc agacaaagct gaacgttcag
  1353181 cccccgccgg tgtcgccgga gcgcgccgcc gagctcgccc gcatgttggc gcttcctgat
  1353241 gtcagccagg tcaccgccga acagatggcg tatcgcggcg aggtgaaggc cgacatcgaa
  1353301 gccgctgaac cggtcgacca ggagcgcgcg gcatgaccat ccagcaccgt acagtcgaca
  1353361 tcgaggctgc gtccgagctc tggaaggaag acttgtcggc ttcccagatc gcgaagcgct
  1353421 tcggtgtgtc tcgcaacgtc atcgtaggga tcgcatttcg aaatcgcgcg ttcttccctt
  1353481 cgaggccgcg agctcgcaac tgccgaccgc acgagagcaa gagagctccg cggaaggaca
  1353541 actgcaatgc gcgaccgcag gcccgatacc acaatcatcc ctccccacaa atatgacctg
  1353601 gagcgactgc cgttcgccaa gtgcctctta gaattgaggc ccggcgagtg cgtttggccc
  1353661 atcaacgacg gcagcccctt cctgttctgt gcagccaaga ctgcggggaa atactgccag
  1353721 caccatcaat ccagagcata tgcagcccat cgcattacga agagggaaaa atgaagagat
  1353781 cacgttggta tccaatccga gttgcgcccg gatataagcg catggagtcc atcatcgagc
  1353841 ggaactgccg caaggacggg ttcgacatct tcatgccgtc attctacacg gagttgaggc
  1353901 atcaccggac gaaacagatc tccagaagcg gttcccgttc ctggttggtt atgccttcgt
  1353961 gaacctgccg agactgaatt tcgaaaagtt gcgcggggtc gatggagtcg tgtgtttcct
  1354021 ccgcggtgcc aactatgggc cgctcgaatt cccggcgcca cgatcgaatc cctatttcgc
  1354081 caagcacgag cgccgtcagt ccgtcttcta cgagcagata catcacctcc gtggtcaact
  1354141 ccggaagatc atgccgaagg gccggaaagc ccgcgtttcc atagtcgacc aggcggaaag
  1354201 gggtatagat tctctaagcg cgcagattaa gagcgggtac aaaaaatcat cagtgaattg
  1354261 aacaacctta ctgctgacca tcaggttgaa aatctccgcc atatcggttt cctgaagtga
  1354321 tctgtggctg ttcagttgcg gacctcgatt aaagggagca ctcgccgggc cttaggggag
  1354381 aactcaccgc tccacgcctg ggctgcattc tgccaatttt cccggttgga tgatcaatga
  1354441 tcctgactgt tgaactcgaa aaggccgagc atcccggggt tgcactatgc tttgaccgcg
  1354501 agggactgga tctcttgata gccaagctcg agactctgcg aaataggcca gaccacatgc
  1354561 atctgatgac gccatcatgg gcaggcgacg ctctcaatga agaaaaggaa ggtggcgagc
  1354621 gatacgagat tgtgaaaagc ttgcgacttg tgcgagttcc gtaaaggctg tcgcactcgg
  1354681 cgcctaggag aaatgcggcc caaaatctat tggcccaatt tacctctgct gcggttagct
  1354741 cttggttttc gacgtgacca cgtaaattgc atctccgacc gtgataacgg cctcggccac
  1354801 gtcgtctgaa atttcgatat tgaactcgtc ctcaatcatc atgacgattt gagcgacttc
  1354861 gagagagtcg gcgccgaggt catccactat ggacgcgtcg tccacagcat gggcagggtc
  1354921 aacgcccaac tgctcgatga ttattgctct tacacgacta gcagcgttcg cgctggagtt
  1354981 ttccaccgat gtcctccctt agagcatgat cacacttatc cgccgtcacg gctcagccgg
  1355041 ccgtcacata agcatagtca tcgcttttct ttattccaat actctcgcac catcgcaggc
  1355101 agggcaactg gtaagccgcg tggttcaaaa cgacgaaaga ccaggttcaa atctccggcc
  1355161 tgcaaccaac acacaatgcg gccaccacgt ctcatcttag aggcgtctga ggaaccactt
  1355221 ccggtacatc gggcggcacc tcattctctg gaacgaacca caggatactc accacgatag
  1355281 cgatgagaac gcagatgagt acgaggaagg caacgccggc tttgtccatg cattattagc
  1355341 agtttcgaat gtgagcaatt cgaggcgatg ccaatcatca ctttcgcgtc gagcagccgg
  1355401 tagctcgcca gcctcggtcg caggtcccaa tcctgtcgcc gcaaccaatc tcacgggaag
  1355461 ggcacgggta gtggactgtt ctgacttctt catccagggc tcaccgggca gttattgctc
  1355521 agtatgcacc gtgaacttcg gagcgtcttc gccggcccct tctgcaagga actcgagcag
  1355581 caccgaaatt aagaactccg cggcctcttt gttcaccaaa aggtctatgg tgcccaggtc
  1355641 ggtctcaaga ttgaggcgcc caatcaatgg ctctgacgaa attgtctgga attcactgtc
  1355701 taacaagcgg ttttcttcca gctctgacat tttcccctcc tgcttagaac gacacgatgc
  1355761 gcaggagttc tgttgattgg caaccaatct agttttgcga tgaccgcaag gacccaacct
  1355821 agctcgctgt aagctcccgg acgcgaaggg gaggcaccaa ccgcagatcg gcacaaccag
  1355881 tttcgaggcg atgcctcacg agattggaaa ggccccgcag ccgtatggcg ctaagccggg
  1355941 tcattggttc accgcatggg ggccgacttt cccgagcaag atcaggtcgg cggatagtta
  1356001 tccgagaaga tcggggttcg tgcctggtcg tcctgtccgg accataagca gccccgccgc
  1356061 cgtgatggtg agcggggctt gcctccatgt ccaagcccta ccgcgtcgta aagctcaaca
  1356121 ctggggagca agacatggac gcggtcctga acgagtgggc ggccaaggga tattggctca
  1356181 atcacgtggt ccggaactcg acctacgact tgagggctga tcttttcttc actcagctga
  1356241 tcgcaaagag cagccacacc agcgtgcacg cagaaacgat gatcatcacg accgccattg
  1356301 cttcaagtgc cttgtgcatc actcttccca gagcatttcc atgatttctt caggcggctc
  1356361 cttcacctgg agagtgacgg aggcgccgtt tttgatcgag caggtgacga gtgtagtgct
  1356421 ccgctgccct tcgacccgtt ggaagtgcat gaccgtgtcc atgttgacga agattggtcc
  1356481 attgttgtcg tgcagttcta gccacatggt tagcgtcctc tcgacgattc gaccgctcgg
  1356541 gtaagtatag cagaggggtg atcgaatggg gcgctaccgc gtcgtcgaat agatgcgcgg
  1356601 ttagtgcaat gtcagcatcg cgaaaaggat gatggccgca agaacgacga ggagaaggat
  1356661 agtaccttct ttcatggcgt tgttactcct gccccagctt agaatatggg gaatctgcag
  1356721 ttcgtcatcc atgcgacgcc tgatcaaatc tcgactatga ggccttggtg catcagttct
  1356781 gtaacgttta cagaactggc attgagagcc tcatcggtat caacatattt atctgaggta
  1356841 aggcacaaga atacggccac cgccctgccg ccttcagcat tcacgtctgg ccgatcaatc
  1356901 gtcacgcctt gatacgtgcc ttgaggtatg gcgtgtccgc ggatctcgca atctccgaga
  1356961 gcttcaaggt taatcaggtg tttagccatg caggcgtttc ctcttttgac ggggctttga
  1357021 cggaagaatg gccaaagcgc aactttctga tgaggtgaaa acctacattg tgcaagcctt
  1357081 ggcatgttgt gacagtccat ctgtcgtggc ggcggcagtc aagaaggagt acggcgccga
  1357141 cgtcagccga cagcttgtcg agagccatga cccgaacaag aaggcaggat cgggcttagc
  1357201 gcgaaagtgg aagacactct tcgaagagac ccgcaagacc ttcctagagg atagcgccat
  1357261 catcgccatc agtccccagg cggtccggct acgcgctctg cagcgcatgg cagagaaggc
  1357321 ggaaacggca atgcgtttcc ctttgtagat ctgcgtggat tgccgttttc cgagagcgcc
  1357381 ctctcggtcg atgatgagag agttggtgat tgctgcgtca gagcgctgga tgtgtttgcc
  1357441 ttctggaaga aataaactgc tgcggcggcc gccgctaaga caagcgacca gaataaccca
  1357501 ggtcttatgg tccccctcaa atgtgacacc cactaaaatg aaacacgagc gagagtggaa
  1357561 gtcgaggacg gtctgcgcta tctatgattt cctcgtgctg ccttaatcgc ttcgaagacg
  1357621 ggaaccatcg caacccgcca aggcaatcag ccgaccagcg ttcacgcctt ttaaacgagg
  1357681 gacttctgga atgggtataa tctggaccat catcatcggc tttatcgcgg gtatcgtggc
  1357741 caagctcatc gtgcccggcg aaaacgagcc aaagggcttc attctaacga cgatcctggg
  1357801 aatcgtaggg gcctttgtcg cctcctatct ggggcaggca ttggggtggt acaacgccaa
  1357861 cgagggtgcc ggcttcatcg gagctattgt aggagctgtg atcgtcttgc tcgtatgggg
  1357921 cgccgtcgcc cggcgtgcct aggacttcac taagcagaaa ggaaccgaca atggcttcgt
  1357981 ctcgcaacac catgccgtcg ctagcggctc tattgggtct gctcgcggtc gctggttacc
  1358041 agaaccgcga taagctcgga cagatctttc aggatgcaaa ggggggcgcc cagaacagcg
  1358101 gcggaattct cggcgaactc ggcaagatgt ttggcggctc cgaggaaggc tcgctcagca
  1358161 agggcgtggg agaacttgtc gatgcattca agaacggcgg acaccgggag gcggcagact
  1358221 cctgggtaag cgccgaagag cgatctcagg gcatttcgcc cgagcaggtc gaatcttcga
  1358281 tcggcaagga tacgctccag gatctggccg caaagaccgg cctggactac aacgaactgc
  1358341 tgaagcgcct ttcgacatcg atcccggacg cggtggacac gatgaccccg aacggccagt
  1358401 tgcctgagac cgatgaggaa gtccttggcc gatcccgcgg ccccactctg ggctagaggt
  1358461 tggttgacgg accggttgcg ctgttccgga ggccctagtt gttcaggctc gatccgcgat
  1358521 ccgtgccgca gtcaaggcga caccgtcggc tatgcggctg cgggcgatcg acgagtaacc
  1358581 catgcggaag aagcggcacg gaccgtcgtc cttggggaag aacggcgatc cggattctat
  1358641 aagcacccct tccaaccgca atgcgttcat cagcagatcc gcatcgaggt catccggccc
  1358701 ttcgatccag aaggaggtgc cgccgaaagc cgccgacccg gcgatccgca agccggcatc
  1358761 ccgaagtgct gccgccatga tgatgtgccg gcgatgatat tcctcgcgca tgcggtgcag
  1358821 cacggcatca tagtggccga gtgccaggaa ataggcggcc gttctctgga ggtgccccgg
  1358881 cggatggcgt agcatcagcg cgcgaagcgc ccgcgcctcc cggatcacgg cggccggcgc
  1358941 caccagataa ccgagccgca gaccgggaaa cagcgacttg gaaaaactgc cgatatagaa
  1359001 gacgcgtccg ctgcggtcga aggccttgag agccggggat gggggcgcca gaaagctcat
  1359061 ctcgaactca taatcgtctt cgacgattat gaagtccttc gaggcagcgg cttcgagcaa
  1359121 tgcagcacgc cggtcgagcg gcatcgtcgc cccggtagga gaatgatggc tgggcgtaac
  1359181 gaataccgca tcgaccttat cgggaagagc ggtgggcggc aggccttcct tgtcgacatc
  1359241 gatgacggtg acttcggcgc cgctcaagcg gagcgaggcg ctcatgtcgg gatgacatgg
  1359301 attctcgcag accgcgtgtg agccctggcg caacagcagt tggatgacga tccacagggc
  1359361 gttttgcgcg ccgaccgtca cgaggatctc gtcggggctc gcacgaatgc cgcgccccgg
  1359421 caatgtacgc gagcagatat agttgacaag ttggacgtca tccgatgccg cgaaatcgcc
  1359481 cgccatcagt tcgaaatcct ctcgcccgag cgcccggcgc gcgcagtcgc gccatgcggt
  1359541 gaggtcgaac agcgatggat ccatctggcc gtagaggaac gggtaggggt aggcgcgcca
  1359601 gtcgaggggt ttgcgcatct gcttggccac tatgaaggtc gagcacaact tggccgacca
  1359661 gtcgatcgta tcggcttcag tgtgcgcggc ccctattgca atgcctgtcg tcggtggctt
  1359721 gccggcgaca cggtagccgc tgcgcttctc cgcctcgata tagccttgcg aggcgagctc
  1359781 ctgataggcg agcgtcacgg tgatccgcga aatgttcaga taggccgcaa gcttgcggct
  1359841 ggaagggagc cgggcacccg ctgccaggcg gccggacaat accgcggaca cgatggtttc
  1359901 ccggatctgc gcctgcaagc ccgcatggcc cgttcggtcc agaaagaaga tcgtttcgga
  1359961 taccgtcgag cccaccattc acatcaccca tggcctcctc caaactggac tcatctaact
  1360021 tcttatctgg atataaggca atccgagagg caggcatatt tctattcctc aagcaaagac
  1360081 cgtcatcaca gtgcggcccg accccgcaat aagcggggcg acagaaccaa gagggaaacg
  1360141 aaatgattca ctacagaaaa ttcaagctta tatccggcgc ccttgcgata gcgaccgggc
  1360201 tgttagccgg ctttgcggcc cgggcggaaa ccagtgtcgt cgtcggctac cagcagatcg
  1360261 tcggcccgtt catttcggca atcgcggatg gccgcttcga tgccgcagcc aaggaggccg
  1360321 gctactcgat cgattggcgc cagttcagct cgggaggcga catttcgacg gcgcttgcat
  1360381 cgggtaatgt gccgatcggc gttatcggtt cgaccggtac gacagccgcc gcgacccgcg
  1360441 gcgtcgagct cgaacttttc tggatcctcg acaatatcgg caaatcggaa gcgcttgtcg
  1360501 cacgcgaggg atccggcatc gcaaagccgg aagatctgat aggaaagaat gtcggcgttc
  1360561 ccttcgtgtc gacctctcac ttccatctgc tggtcggcct gggagaggtc tggaaaatcg
  1360621 atccgcggga agtgaacatc ctcaacatga agccgccgca gatcgtcgcc gcctggcagc
  1360681 gcggcgatat cgacgccgcc tatgtctggc cgccggccct ttcggagctc ctgaaaacgg
  1360741 gtaaggtgat ctcggattcc gaggcggtcg gcgcggcgag cgtgcccaca ttcgacggcc
  1360801 tcgtggtcga taagaaatgg gccgaggaaa atccggattt catggcggcc ttcaccaggg
  1360861 tgctcgccga gtcctatgcc gatttcaagg ccaatggaag cggctggacg gcggactcgc
  1360921 cggaggtgca gggcatggtc aagttgatcg gcggcgacgc cgagggtatc gtccaggccc
  1360981 tcaaccttct atccttcccg accgccgagg aacaggtctc cgacaggtgg cttggcggcg
  1361041 gtgccgtccg ggcactggag gcgagcgcca ggtttctggt cgagcagaag cagatcgaca
  1361101 atgcgctcga cgattacgcg cccttcgtca acagcgccta cgcgaaagaa gtctccaagt
  1361161 agcggaagcg cgctcccggc tgctgcgcgc tgtgcgtgtc cgggagcatc gctgctgccc
  1361221 tcgatacagc actttccagg aaggcccgcg acatggaaac gctcaacgtc agcaatgtca
  1361281 atttgaccta tcccggtctt tattcggacc aggcggtcat cgcgctcaag ggcgtgaatc
  1361341 tcgagatcaa gagcggcgac ttcgtcgtcg cgctcggtgc atcgggctgc ggcaagacca
  1361401 cgctcctcaa cctgatggca ggtttcatgg cgccgagcgc cggggagatc acgctcggtg
  1361461 agcgccgcat caccggtccc ggcgccgacc gaggcgttgt ttttcagaag cacgcgctgc
  1361521 tcccctggct caatgtcatc gacaataccg agttcgggct caagctcagg ggtgtcgaca
  1361581 aggcaacaag gcgggaggtg gcgacgcgaa acctcgcgct cgtcgggctg caggatttcc
  1361641 accggcacat gatctaccac ctttccggcg gcatgcagca gcgcgtcggc atcgcccgcg
  1361701 cgctcacctg cgatccggcg atgctgctca tggacgagcc catggccgcc ctcgatgcct
  1361761 tgacgcggga gaccatccag gaactgctgc tgaaggtctg gcagctcacc aacaagatgt
  1361821 tcttcttcat tacccacagc gtcgaggagg cgctgttcct cggctccagg ctgatcgtga
  1361881 tgtcgccccg accgggtcgc atcacccata cctacgagct cgatttcaac aaacgcttcc
  1361941 tggagaacgg ccatgcacgc gcaatcaaat ccagccgcga cttcatcgac atgcgtgaac
  1362001 aaatcctcgg catcatctac ggggacgagc gccagtccgg taacccggag ctcctccatg
  1362061 cttgagggcg tcgtcaagag caaacccgtt cggccgggac gaatctacgg cgcaccgggc
  1362121 gacgggatga gcggccatat cagcctgttg actgcgctgg tgctgatcgc gttttggctg
  1362181 ctcgtgacgg agatgggctg gatcaaaccg ctgttcctgc cgtcgccgct cgcagtctgg
  1362241 gacaagttcg tcatagcact gacggaaggg gtctccaact ccaccttggc gcagcacacg
  1362301 ctggcgagcc tcggccgggt gttcggagcc tttctgcttg cgctcgtcac ggcagtcccg
  1362361 gtgggcattc tcatgggcgt caatcgggtg gtgcgggggc ttttcgaccc catcatcgaa
  1362421 ttctaccgcc cgctgccgcc gctcgcttat ctgccgctga tcatcatctg gctcggcatc
  1362481 ggcgaattcc cgaaagtttt cctgatctat ctggcgatct ttgcgccgat ggcgatcgcc
  1362541 gccagagccg gtgtgcgctc ggtctcgacg gaacagattc atgccgccta tgccatgggc
  1362601 gcgactcggg cacaggtgat cgggcatgtg atcatgaagg ctgcgttgcc ggagatattc
  1362661 accggtatgc gcatcgggat cggcgtcggc tggaccacgc tggtcgcggc cgaaatggtg
  1362721 gccgcccatc gtggactcgg cttcatggtg ctgaatgcag ccgaatatct cgccagcgat
  1362781 acggtcatca tggggatcgt cgtcatcggc gtgttcgcct tcgccttcga cctcatgatc
  1362841 cgctacctcg aaaagacgct cattccctgg aagggcaaag tgtgatggcc gccgatcggc
  1362901 agtagtcggc gccgccccgg atagcctcga ttcaagcatt ttaacgggcc tatggccgcc
  1362961 cgaccggcga agccatgccc cgacatgaac aaaggaattt cgacatgacc gccgaggacc
  1363021 tcgcagagct tttcgacgcc ttcaacagac acgacatcga tagtgtcatg gcatttttcg
  1363081 ccgccgactg tgtcttcaac gccgttgccg ggccggaggc ctgcggcaag cgcatcgtcg
  1363141 gcgccgaggc gattgccgat gccttttccg gtgtatgggc ggcaatgccg gacgctcatt
  1363201 gggatcatca cagccatttc gtccatggag accgcggggt ctccgaatgg accttctcgg
  1363261 ggaccaatgc ggacggcacg cgcatcgtcg cggaaggctg cgatctcttc acgcttcgcg
  1363321 acggcaagat cgtccgcaag caggcattcc gaaaaaaccg gccgctcatc gagccgcagc
  1363381 cgagatactg agcgccttga gggcaggatc acgacatgga acaccagctg gccagaccga
  1363441 tcgcatcgcg caagcccttc gacccgacct atgatccgat ccgcgcgccc aatccgggcg
  1363501 agggcaagga ctatgcgccg acctattgga ttggcacggc cggcaaaccg ccttccgacg
  1363561 acggccccgt cacatgcgat atggacgtcg acgtcgctat cgtcggctcc ggatatacgg
  1363621 ggctctcctg cgcgatccat ctcgcccgcg agcacggcat aaaggcgacg gttctcgagg
  1363681 caaacggcgt tgcctggggc tgcagcaccc gcaatggtgg ccaggcgcag atctccgcag
  1363741 ggcgcctcaa gcgctcgcaa tggatcgagc gatggggcgt cgatatcgcc aaaaaactgc
  1363801 acgtcgagat cagcgaagcc ttcgatctct tccgagacct gatccgttca cccgaaatcg
  1363861 actgcgatgc tcaggacggc ggccacctct atatcgcaca tcgcgacaag gtgatgccgg
  1363921 cgctcgaaag cgagtcgcgg ctcctcaacg aggtcttcgg ctaccgttcg cgcatcgtcg
  1363981 ggcgagagga ggtccaccgg gacttcgtcc gcgacgagga ggccaagggg gctatgtacg
  1364041 aaccggacgg gatggggatc cacgcagcca agctcgcctt cggatacctc aatctggcgc
  1364101 gcaagctcgg tgcgcgggtc catacggcga gccccgttct cacctgcgac tggaaaaacg
  1364161 gcgcctatca cctgtctacg ccgggcggca ccgttcgtgc acgcgccgtc tgcattgcga
  1364221 cggcgggcta tacctcgccg gatctccata gtttgacgcg gcaccggctc atgccgatcc
  1364281 tctccaactc gatcgtcacc cgtccgctga acgaggaaga gcgctccgaa ctgaacttca
  1364341 agacgcggat accgctcaca gatacacgca cgctgcggca ctattacagg ataatgccgg
  1364401 acggccgcgt gcagatcggc agccgcagcg ccataaccgg ccgcgatgcg gtgaatccca
  1364461 aacatctcgg tcggcttctc gaagggctct accgaaagtt cccggtcctg aagggaatca
  1364521 cgatcgacta ctcctggtgg ggctgggtcg atgtcagcca cgacatgatg ccacgcatct
  1364581 tccggcccga tccgaagcag ccgctgttct acgcgatggg ctatggcggc aacggcgtca
  1364641 tgtattccgc ccaggcggga cgtcgaatgg cacagatggt tgcgggccag ggcggcgccc
  1364701 tcgatctgcc gatcttcacg tcgccgctgc cgagccatgg actgctcacg ccgttcagac
  1364761 gcctcggcca gtggggcatg tatcgctggt actatctcaa agacgagatc ctgtaaccgt
  1364821 gcgcgggtca gaacgtttgc gcgagcttgc gtgccgccga ctgaagcacg ggcacgtagc
  1364881 gcttggagtc gtcgagcgtc atgcgggctt tcggggcgtg gcaggcaagc gacgcaacca
  1364941 cccttccgtt tctgtcgaat acgggaaccg cgatggctat caggccgatc atgaactctt
  1365001 cccggtcggt gctgtagcca tcgcgcaaaa tctctgcgaa ctcgctctcc agcgcgtcgg
  1365061 cagacatgat cgttgcaggc gtgaatcttt caaaggtcag cgaggccagc agcttctgcc
  1365121 tttgctgcac atccatatgc gcaagcaaca atttgccgct ggcggtgcag tgaagcggca
  1365181 cgcgcgaacc gggctcgaga tgtactcgga gcggccagtc ggattcaacg cgcgccagat
  1365241 atatcgcgtc gcagccggag cgcgtcacga aattgcatgt ctcacgcgtc acatcgacga
  1365301 cctgcttcaa tatggcgtgc cgctgggtcc ccacgcccga accgacgatg gtcaggccca
  1365361 tcttgaacag gcgcgggccg accgaatagt ggcgtctgtc aggttcgcga aagaggaatc
  1365421 cttcctcgac caggcgctgg cacagcctgt gcagcgtggc cctgggcatg tcgatcctct
  1365481 ccgcaagatc gttcagcgtg accggctttt cggaaagtcc gacgacttcg atcaggctga
  1365541 ggctgcgcgt aacggccgaa ttcggcgtct cgattttatc gtccatcctc attcctttgt
  1365601 ctcacttatt gagattcaat ttgggtacaa tcgctatcat atagctaatc ttacctcaat
  1365661 atctcattca gtaggatatt tcatctcaga aaaattgaca catcgcgctc cttatctctt
  1365721 ttgtgggatg agggaggagc cgaacgtgaa cgaagcgcaa tttgattaca tcgtggtcgg
  1365781 tgccggctct tcgggctgca ccgttgccgc acgtctctcg gaagacggca ggttccgtgt
  1365841 tgctctcgtc gaagcggggc cgaaagacac cagcccctgg attcacttgc cgctcggtta
  1365901 cggcaagacg atgtgggatg agcgcatcaa ctggaagctt tacaccgagc ccgatcccaa
  1365961 catgaacggc cgacgcatct attggccgcg cggcaaggtt ctggggggct gctcggcgat
  1366021 caacggtctg attgccatcc ggggacaggc cgaggactat gacgactggg cgcgctacgg
  1366081 cggggatcag tggaactatc gcaacgtcct gccccatttc cgtaagtccg aatccttcgc
  1366141 gggcgccgca aaccccgagt tccacggcaa gcacgggccg atctgcgtcg ctccgatccg
  1366201 ccaccgtcat ccgctgatcg acgcattcat cggctcggcc aatcagcttg gcatcccctg
  1366261 caacgatgat ttcaacggtc cgtcgcagga aggcgtgggc tactacagcc tgacgaccag
  1366321 aaacggaatg cgcagcagcg cggcggtggg ttatctccgc ccggcaaaac ggcggagcaa
  1366381 ccttacgatc gtcacggaag cgctggtcac gaaagtccgc tttgaggggc gccgggcgca
  1366441 gggcatcgac tacactacaa atggtcgcaa gatgagcatg aatgcgcggc gtggcgtcat
  1366501 ccttagcgcg ggcgccgtgc atacaccgca cctgatgatg ctgtccggca tcggaccggc
  1366561 cgcgcatctc aaggctcacg gcatcgacgt cgtggcggac atgcctggcg ttggtgctaa
  1366621 tctgcgagat cacctgcagc tccggcttat ctatcgctgc aacagaccca tcaccacgaa
  1366681 tgacgaactg aacagtctga ccggcaaggt gaaaatcgga ctgcaatggt tgctgacgcg
  1366741 aactggaccc cttgccgtcg gcatcaacca gggtgggctc ttcgccaggg tcatgcccga
  1366801 tgcgacgcga cccgacgttc aatttcatgt cgccacactt tccgcggaca tggccggagg
  1366861 aaaagtccat cccttctccg gctttaccat gtcggtctgt cagctccggc ccgagagcca
  1366921 cggcaccatt cggctggcct gcgcggaccc cacgacaccg ccgctgatac acgccaatta
  1366981 tctcgacgcc gaactcgacc gtcagattgc gatcggcggc atcagactgg cccgccgcat
  1367041 cgcgcgcaca ggtccgctga gccagctcgt aacccgcgaa gaactgccgg gcgagtccgt
  1367101 cgacagcaag gaaggaattc tcgatttcgc gcgccagaac ggcgcaacga tcttccatcc
  1367161 aacgagcaca tgccgaatgg gccaggacga cgatgcggat gcagtggtcc gccccgacct
  1367221 gaaagtgaga ggcttcgacg gcctttggat cgcggattgt tcggtgatgc ccaccatcgt
  1367281 gtcgggaaac accaacctgc cggcaatcat gatcggagag aaactgtcga gctcaattct
  1367341 gaactgaaat ccgacattgg gaggagacca tgttgaatac cgctgggagc accagggaaa
  1367401 gtgaagtgag gcgtgtcgtt ttcgcgtctc tgataggcgc aacgatcgaa tggtatgact
  1367461 tcttcttgta cggcgtgatt gccggcatcg ttttcaatca gctgtatttc ccgtcgcacg
  1367521 acccgctcgt ttcgatggtg ctggcctatg cgacctttgc cgtaggtttc gtcgcccgtc
  1367581 cgctcggcgg catcgtattc ggacatttcg gcgacaaact cggccgcaag cagatgctcg
  1367641 tactcaccat tctgatcatg ggggtggcga ccgtgctgat cggcgttctg cccacctacg
  1367701 agcagattgg tgtggcagcc cccatactgc tgctcatcct gcgtatcgca caaggcatcg
  1367761 gcattggcgg cgaatggggc ggcgcagtcc tcatggccta cgaattcgca cctgaagaca
  1367821 agcgcggcta ctatgcatcg atcccgcaga tcggccttgc gatcggattg tgcctgtcgt
  1367881 ccggcgtggt ggcgctcctc agtcttctcc ccgaagcagc cttcatgtcc tggggctggc
  1367941 gcactgcttt catcggctcg gtcgtcctta tcgtcgtcgg cctttacatc cggctgaagg
  1368001 ttgccgaaac accggatttc gccagcgtca aggaagagcg acaggagctc aagatcccgt
  1368061 tcgtggagct catccgcacc tatcctcgca atatactgct cggcatgggt gcccgctata
  1368121 tcgatggagt tttcttcaac gtattcgccg tcttctcgat cgtctatctt tccaagcatg
  1368181 tgcaggtgga ccgcacgacg gcattgtggc tcgtatgcct ctctgcactc gtcatggtcg
  1368241 tgacaattcc gctgttcggc aagttgtccg atcgatgggg gcgtccgaaa acctacgcca
  1368301 taggcagtct tctgctggcg ctggtcacct tcccggcctt catgctcatg ggaagcggga
  1368361 gcctgccgtt gatcgcactc gctctgatcg tgccgttcgg catcatctac gcaatgtgct
  1368421 acggccccga agcggcactg ttctccgacc ttttcgacgt taaggtccgc tataccggca
  1368481 tttccttcgt ctatcagttc tccggcatct tcgccagcgg catcacgcca atcatcgcga
  1368541 ccttccttat cagctatggc gacggctcgc cctggctgct ggccgcctac gtggtgtttg
  1368601 cggctcttgt ttcgatggtt tcggcgatgc tcatacgtcc ggtttcgcaa atgcgtacca
  1368661 ccctgccgca taagccgttg cgcccatcac ccgttcacac aagctaagga aacagccatg
  1368721 aaaatgacca ccgaagaagc cttcgtcaaa gtcctccaga tgcacggcat cgagcatgct
  1368781 ttcggcatca tcggctcggc gatgatgccc gtatcggatc tctttccgaa ggcgggcatc
  1368841 aaattctggg actgcgccca tgagaccaat gccggcatga tggcggatgg cttcagccgg
  1368901 gccaccggga ccatgtcgat ggcgatcggc cagaacggtc ccggcgtcac cggcttcatc
  1368961 accgccatga agacggccta ctggaatcac acgccgctgc tgatggttac gccgcaggcg
  1369021 gccaacaaga cgatcgggca gggcggcttc caggaagtcg accagatggc catgttcgag
  1369081 gagatggtct gctatcagga agaggtgcgg gacccgagcc gcattcctga agtcctgaac
  1369141 cgagtcatcg agaaggcctg gcggggttgt gcgccggcgc agatcaacat ccccagggat
  1369201 ttctggacgc atgtgatcga cgtggatctg ccgcgtatcg tccgcttcga gcggccggcc
  1369261 ggcggaccgg cggcgatcgc gcaggcggcc cggctgcttt cggaggcgaa attcccggtc
  1369321 attctcaatg gcgccggtgt cgtcatcggc aatgcaattc aggaatcgat ggcgctcgcc
  1369381 gaacggctga atgcaccggt gtgctgcgga tatcagcata acgacgcctt tccgggcagc
  1369441 catcgcctgt cggtcgggcc gcttggctat aacggctcga aggcggcgat ggaactgatc
  1369501 agcaaggccg atgtcgtgct ggcattgggc acgcggctca accctttctc gacgctgccg
  1369561 ggctatggca tcgactactg gccgaagaat gcgtccatca tacaggtcga catcaatccc
  1369621 gaccggatcg gcttgacgaa gaaggtgacg gtcgggattt gcggcgacgc gaaacaggtg
  1369681 gcgcagcaga tccttcagca gcttgccccc gtcgccggcg aagcaagccg cgaggaacgc
  1369741 aaggcgctgg tccaccagac gcgctcggcg tggctgcagc agctctcttc gatggaccac
  1369801 gaggatgacg atccgggtac ggagtggaac gttggggcgc gccaacggga gcccgatcgc
  1369861 atgtcgccgc gccaggtctg gcgcgcgatc caggccgtgc ttccgaaaga ggcgatcatc
  1369921 tccaccgaca tcggcaacaa ctgcgccatc ggcaacgcct atccgagttt cgagcagggc
  1369981 agaaagtatc tggctcccgg catgttcggc ccctgcggct atggcttccc gtcgatcgtg
  1370041 ggcgccaaga tcggctgccc ggatgtgccg gtcgtcggct ttgccggcga cggcgccttc
  1370101 ggcatctcga tgaacgagat gacgtcgatc ggccgcgagg gatggccggc catcaccatg
  1370161 gtaatcttcc ggaactacca gtggggtgcc gagaaacgca atacgacgct ctggtacgac
  1370221 aacaacttcg taggcaccga gctcaatccg aacctgagct acgccaaggt tgcggacggc
  1370281 tccgggctca aagggatcac cgtcgacacg ccggccgcac tcaaggaggc gctttcgaag
  1370341 gcgatcgagg accaggccag gggtatcacc accttcgtcg aggtcattct caatcaggaa
  1370401 ctcggcgagc ccttccggcg cgacgcgatg aagaaaccgg tggcggtggc gggcatcgat
  1370461 cgggccgata tgcagcccca gagccgcagg tagtcctgca tgcgcgatat ccggcggcct
  1370521 ctgccgccgg gcacactcaa cgggaagaat agatggacgc gatctccaga accgagcgac
  1370581 cgaagcaatc ccccaaagcc gtcctgtcga cctatggccc cggcctcctg gtgacggcgg
  1370641 ccgtcgccat ggctgctcag ttcctctccg agcactatgg ggcgccggcc atgctgatgg
  1370701 cgctgctgct cgggatcgcg ttccacttcc tggcggaaga gggacgatgc gtcgccggca
  1370761 tcgaactctc ggcaaaactg gtgctcagga tcggcgtcgc gctgctcggt atgcgcatca
  1370821 gcgtcgatct gctgatcggc ctcggcgcgg gcaccatcct cctccttgta tcggcgattg
  1370881 ctgcgaccat cctgttcggc ctcgtggccg cccggctgct tggccggggc tggcgccttg
  1370941 ctctcctcac aagcggcgcg gttgccatct gcggagcctc ggcggccatg gccatcgcgt
  1371001 cggtgctgcc tcgcaacgag ttttccgaac gcaacctgat ctttaccgtc ctgtcggtga
  1371061 ccgtgctcag tacgctcgcc atgatcggat acccgatcgt cgccgaatat ctcgggcttg
  1371121 atggccaggc gaccgggata ttccttggcg gcacgatcca tgatgtcgcc caggtcgtgg
  1371181 gcgccggctt ttcggtgtca ccggaggcgg gcgagacggc gacgctcgtc aagctcatcc
  1371241 gcgtgacgat gcttgcacca gtcgtcctca tcttctcggt cgcgctgcgc ggcgttccgc
  1371301 aggagggcac ctcgatagga aggcgcgccc cgctcgtccc cggcttcgtg ctggcgtttc
  1371361 tcatactcgc gggtttcaac tccgccggtc tggtgcccgt cctggtgagc gaaatcggaa
  1371421 tggaaatctc gcggtgggcg ctgctggcgg ggatcgtggc cgtcggcatg aagacatctc
  1371481 tgcgtcgcgt ccttgaggtt ggcggggatg ccgtcgcact cgtcgtcgcc gaaacgctgt
  1371541 tcatcgccgt cttcattctt gtcggcatga attatctggg acacagctga tgaaacctct
  1371601 cgaccggatt atcgaaacgg caaggaaagc cccgcgacac attgttctct ccgaagggga
  1371661 ggacccgcgg atcgtcgccg gcgccgtacg tgcgaggcgg gaatgtctgg cggagatcac
  1371721 gctcgtcgga aaccgcgagg tggtcatgca caggctcgca gctctggatg caaacccgcg
  1371781 agaattccgg gtggaggacc cgtcctcctc gtcgctcacc gacggtttcg cggcttcctt
  1371841 tctcgacctc agaaggagca aaggcgtcga cgaggccgcg gctcgggtgg cggtgctcac
  1371901 gccactgaac ttcgccgcga tgatggtgag ggaagggctg gccgacggaa ccgtcggcgg
  1371961 tgcggtcgcg accaccgccg ataccgtgcg cgccgccctg caggtgatcg gtagggcgcc
  1372021 cggcgtcggg ctcgtctcca gcttctttct gatgatgctc tgcgaaccgc atcacgcccg
  1372081 caagggtgcc ttcgtcttcg ccgattgcgg actggtggtg gatcccgatg caggcggcct
  1372141 tgccgacatc gcgcttatgt ccgcgaaatc ctatgagcag cttgccggcg agcgggctaa
  1372201 agtcgccatg ctctctttct cgaccggcgg cagcgccgct catgagcgcg tttcgaaggt
  1372261 cgtcgaggcc acccgcatgg cgcgatgcgc tgagcccgat ctcgttatag acggggaatt
  1372321 gcagttcgac agcgccttcg tcgaagccgt ctccctgacc aaggcgccgc aatccgcgtt
  1372381 gcgcggggag gccaatgttt tcgtgttccc gaatctcgac gcggcaaata tcggttacaa
  1372441 gatcgcccag cggatcggcg gagcgacggc gatcgggcca attctgcagg gactggcacg
  1372501 gccggccaac gatctttcgc ggggctgcag tgccgacgac gtcttccaca tgattgcggt
  1372561 tacagtcgtc caggggcgtg aggacaactc caccgtttcc gaaaggcgtc aaaacgtcac
  1372621 ataatgcaaa aagtgtatta tgcagccttt gcaatatttg cgacatccct tgcggcctgt
  1372681 cgcgaatatt gcaacattgt cggcatgtcc agatcagcga actcccgggc gctcgcgccg
  1372741 cgccgtcatg aggaaattct aaggcgcctc gctgccgaag gctcggtgag catcgcggag
  1372801 ctttccgccc atttcgacgt ctcgcgtgag acgatccgcc gcgatatgaa gttgctggct
  1372861 gaccgcggcc agctcgacgt ggtgcatggc ggggccacat tgttcgagcc gatcgagccg
  1372921 gcgttggttc accgaagcga ggaaaacgcc accgccaagg cagctattgg cctcaaagcc
  1372981 gccgaactgg tgaaggacgg catggtcgtg ttcctcgatt caggcacgac cacgcttgcc
  1373041 gttgcccatg cgctagacgg gcttcgcgac ctgaccgtct gcaccacggg ccttgccatc
  1373101 gcactgcata tgtgccggca accgcgcgcc cgggtccata tgctgggcgg cgagatcgat
  1373161 cctgcggagg aggcggcagt cggcctggac gcgctggagg cgatcggccg ctttcgggtc
  1373221 gatatcgcct ttctcggtgg gggcgggctt tccccggacg gcgaggtgac cgatttcacg
  1373281 cgcaatggcg ccgagcagcg ctcgcgcatg atcgccatgg ccggcaaagc ctatttcgtc
  1373341 ctggacagct cgaagttcgg aaggctgacg ccacttcgca tacccgggtt tcatcaggcg
  1373401 gccggtgtca tcgtagatgc gccgccagcg ccgacgatct cggaagcgct cgagcggaaa
  1373461 gggccacggg tgatcgtcgc caccagatga atgttgcata atgttgcaat tcatgttgcg
  1373521 ttttgcggat ggccaactat cctgaagcca gtcaatcggg aggatggttc atgccgcagg
  1373581 aatttccaac gcaggcgcgc gtcgttatta tcggcggcgg tatcataggc tgttcggttg
  1373641 cctatcatct cacacagctt ggctggaccg acgttgtcct ccttgaacag ggtcaactca
  1373701 gcggtggaac cacctggcat gctgcgggtc tcgtcggaca gttgcgcagc catgccaaca
  1373761 tgaccggcct catccggtat tcgacgcagc tctacagcga gctcgaggca gagacaggtc
  1373821 ttgcgaccgg atggaagaat tgtggctcgc ttgccgtcgc ccgcacggcc gaccgcatga
  1373881 ccgtgctgaa gcggaccgcc gcctcggccc gggcccaagg ggtcgccgtc gaggtgattt
  1373941 cgccccgcga agcagccgat ctctggccgg tgatggcggt agaggatctc gtcggcgccg
  1374001 tctggctccc gggagacggc aaggccaatc cgacggacct cacgcagtcc ctggccaagg
  1374061 gcgcgcgcaa tcgcggtgcc cgtattatcg agcgggtgcg cgtgaccggg ataacggcca
  1374121 aggacgggac ggtccgcgga gtcgagacgg atcggggcag catcgccgct gaaatcgtcg
  1374181 tcaattgcgc cggccaatgg gcgcgcaagg tcgggctgat gtgcggcgtg accgtaccgc
  1374241 tgcactccgc cgaacacatg tatatcgtca cgggcaagat cgagggcgtg catccggacc
  1374301 tgcctgtact gcgcgatccc gatggctaca tctatttcaa ggaggaggtc ggcggtctcg
  1374361 tcatgggcgg cttcgagccg gaggccaagc cctggggcat gaacggcatt ccggacgatt
  1374421 tcgaattcgc attgctggaa gatgactggg accagttcga agtcctcatg cagaatgcac
  1374481 ttatacgggt accgcaactc gaaacggcgg aggttagaaa gttctacaac ggtccggaaa
  1374541 gcttcacccc ggacaacaat ttcatcctcg gtgaggcacc ggaactgcgc aacttctatg
  1374601 tcggtgccgg cttcaactcc atggggatcg ccagtgccgg aggcgccggg cgggcgcttg
  1374661 cggagtggat cgtcaatggt gctccgacga tcgatctctg gccggtggac attcgccgtt
  1374721 tcgcgcgctt caacaacaat ccacgctggc tgcatgatcg ggtgaaggaa acgcttggcc
  1374781 tgcattatgc catgccatgg ccgaaccgcg agttgcacac ggcacggccc ttccggcgct
  1374841 cgccgcttta cgaccggctt gcctcaaggg gtgcgtgttt tgggtcgaag atgggttggg
  1374901 agcgcgccaa ctggttcgcc gaagcgggcc aggaagcgga aacggactac gccttcggtc
  1374961 gccagaattg gcacgaagcg gtaaagcgtg agatgagggc gacgcgccag gccgctggaa
  1375021 tctttgatca aacctctttc gccaaattgc tcgtgcaggg gcgggatgca gcaaaggctc
  1375081 tcaaccgcat ctgcgccgcc gatattgatg tcgagatcgg ccgttcaata tacaccggca
  1375141 tgctcaacgc gcgcggcggc tatgaaagcg acctgacggt gatgcggctt gcacccgatc
  1375201 ggttcctcat cgtgaccgga tcggcacaag ccgtgcacga tgcagactgg atacgcagaa
  1375261 atatcccggt ggatgcgcat gtcaccctga ccgatgtgac gtcgtcctat gccgtgctgg
  1375321 cgctgatggg gccgaacgcg cgcgacatcc tcggacggat cacctctgcc gatctttcga
  1375381 acgcgggttt tcccttctcg accatatgtg agatcgacat cggctatgcg acggccttcg
  1375441 ccaaccgcat gacctatgtc ggcgaactcg gctgggagct gatcgtaccc agcgaattcg
  1375501 cggtgggcgt gtatgaggcg ctacacgagg ctggtcgtga cctcgggctc atcgattgcg
  1375561 gctattacgc tctcgaggca ctgcgtatcg agaaaggctt ccgtgcctgg agccgcgagt
  1375621 tgacgcccga catcaatccc tatgaagcgg ggctcgcctt tgccgtatcg ctcgacaagc
  1375681 cgggtggctt catcggccgc gaggcattgg tccgcgccag gcaggccggc ccccctgtca
  1375741 agcggatcgt gcagttcacc ttggatgatg cagagccgat gctttggggc ggcgaactca
  1375801 tcctgcgcga cggcaagccc gtcggcgagg tcaggtcggc tgcctatggc cacacgcttg
  1375861 gtcgctcggt ggcactcgga ctcatcgaac atgatgaagg cgtcggccgg gagttcatcg
  1375921 gaaacgggca tttcgagatc gatcttgcag gtgaccgcca gtccgccacc gctcacctga
  1375981 agtgccccta cgacccgaag tccgagcgcg taagggtaga tgctgatgaa ccgcgggcgg
  1376041 cagcctgagg ttcacttctc cgccagggag cgggcgatct cgaagaaggc gcgcacgagc
  1376101 tttccgccgc tgcgctcctt caggcagatc agagcctcgt ccatcagcat ctcagctcct
  1376161 ataatttcga tcggggcgag acgtccgtcc cgaccgaatt cggcagcgga gacaaagccg
  1376221 acaccggccc cggccgcgac gatctccctc acggcctcac gaccttccgc ttcgatggcc
  1376281 ggcttcagcg cgacaccggc ggcggcggca aagtcctcga gcttctgccg cgtcttcgaa
  1376341 ccccgctcgc gcatgaccag cggctggccc gcgagttcct cgagactgac attgctgcgg
  1376401 caggcgatcg gatgttccgt cgacgcgaat gcgatgatcg gcgtggagtt cagtttgacg
  1376461 atgtcgaatt cccggctttc gggaatctcg ccgagaacgc cgatgtccgc ctcgtaggaa
  1376521 tagagacttg tgatgaccgt ttccgtgttg ccggccctca gcgagatctg caccgtcgga
  1376581 tatttcttgc gaaaggcggc aaggatgtgc agcagatgat gggcggcgtc ggcgacgatg
  1376641 cgaagtgttc ccgcgcgcag cgcgcgcgat tccgaaagca gatcgagcgc ctgctgttcg
  1376701 gtgtcgaaca tgcgccgggt gatctccagc aactggtggc cagcctgggt cagcgtcacc
  1376761 tgcttcttgt tccggttgaa gaggaggacg tcatattcct cctccagctt tcggacctgg
  1376821 tccgatacgg ctggctgggt gaggaacaaa gcctctgccg cccgggaaaa gcctccacag
  1376881 accgcaacat tatggaacgc gcgaagctgg acatagcgca tgggatgggg tccaatcata
  1376941 agctcatcta atgaaacgat agaaacgaac gatttgattt atgtaaagag aaaagtgacg
  1377001 gtcagccgga atgatttccg gagcgattga aaatgactgt cattactctc tcgctgcatc
  1377061 tcgccggcgc gaccgtgctg ctgctttacg ccgtgcatct cgtccgtagc ggcgtcgaga
  1377121 acgcctatgg gccttctctg aagcgtgtgc tggcgaaagg aggggagcgc cgcgtttacg
  1377181 ccgccgcgag cggcacggcc cttgccgtcc tgttgcaaag ctccaccgca gtggcgatgc
  1377241 ttgcctccgg ccttgccgca agcggctatc tcacgctgaa caccagccta gccgttctgc
  1377301 ttggagcgga tttcggctcg gcgctggtgg tccgtgtcct atcgttcgat ctcggctgga
  1377361 tgtcgccgct gctgcttgcg gccggtgggc tttgttacct gaagggaaga accgacaaat
  1377421 ttcacgaaat cgggcgcatg ctgctcggta tcgccttcgt cctcatgtcg ctgaagctga
  1377481 tcggcgaggc gacagtgccg ttgaagagga gcgaagtgct gcctgctatc gtcgggtatc
  1377541 tcgccgaaga ccaggtgatg tccttcgtcg ccgcggcgct cttcacctgg atcgttcatt
  1377601 cgagcgtcgc agttctgatc ctcatcctcg gtttcgccgc acagggactt ctgccgatcg
  1377661 aggcgggcct gccgttgatc ctcggagcga atctcggcag tggaatgatc gccatttggc
  1377721 tgacacgcgg ctttccagcc gaggcgcgac gcgtggcggc gggcaacttc ctcttccggg
  1377781 cgcttggcgc cgcgatcacc ttaccggtct gcggtgtttt ggcgggccgc attcaggctc
  1377841 tgggcaccac ccctgcggag cagctcgtcc attttcatct ggtcttcaat gcctgcctgg
  1377901 tgctcatttg ccttccgctt tcgcagcttg ctgccggcgc cgtctcgtca ctcgtgaagt
  1377961 cggaccctgg acgcttcgac gataacgacc cgctcgccgg tcgcatcagc gctctggacg
  1378021 aggggttgct cgacagcccc gatgccgctc tcgccgcggc aacgcgcgag gtgctgttca
  1378081 tgggtgaaat ggtcgagcgg atgctttgtc cggtaatgga gcttctggag catccaaatc
  1378141 gaagaaagct tgaagagatc cgccgtctcg acgagcacgt caatcgcgcc caccgcggta
  1378201 tcaagctcta tctcgcagcg atcaaccgcg gcgtgcttga tgagccccag tctcggaagg
  1378261 gagttgagtt gatcgatatc gcgatcaacc tcgagcatgc cggggacatc gtctccaaga
  1378321 cccttgtgga aatcgtccgc gacaagctgg agaacggcaa cagcttttcc aatgaaggct
  1378381 ggaccgagct caaaatgctt catgccagcg tgcgcgacaa tatgcgtctc gcattcaatc
  1378441 tgctggtttc gggcgacccg gccatggcgc gcaggctcgt gcgcgagaag gagcgagtgc
  1378501 gtgggctcgt gcgcgaaagt cgcgaaaggc acctggcgag gctgcgggca gggcgccccg
  1378561 aaagcgtcga gtccagcaat atgcacctcg aaatcgcgcg cgcgctcaag gaggtgaatt
  1378621 ctcttctcgc aacgcttgcc tatcccattc tgaagcagag aggcgatctg ctcgaaagcc
  1378681 ggctcaggct ggcgaaggta tcataagcag aaactatgcg tgaatataaa atatcgattt
  1378741 tacagataca ttccggcccg ccatcctcgc ccccatcccg gcagttctca gaggagagaa
  1378801 accagatgcc agcagatgca aagacgaata atgctctcga agcgccgaga ttgggagagc
  1378861 catacctgct gacgccggga ccgctcacga cagctttttc cgtcaaggag gcaatgctgc
  1378921 gcgactgggg ttcctgggac ggcgacttcc gggcgatgac ggccgagctg agacgcgaac
  1378981 tgcttgcgat cgccgaagat gagaccggcg agttcgattg cgtcccgatg cagggcagcg
  1379041 gatccttttc ggtcgaggcg atgctcggca gcttcgttcc ccgcgatggc aaggtcctgg
  1379101 tgctgatgaa cggcgcctac ggccagcgca tcgcccagac gctcaaatat ctaggccgtg
  1379161 cttatgtcgc ggtcgacaag ggcgactata tgcctccgcg cggcagcgag gtcgcagctg
  1379221 ccctcgacgc cgatcccgca attacccatg tggtcgtcgt ccattgcgag acgagttccg
  1379281 gaattctcaa ccctctcaag gaaatttccg aggcggtcta cagccgcggc cgcaagctgc
  1379341 tggtcgacag catgagcgcc tttggagcgg tgcctgccgg tgtccttgac ttccgttacg
  1379401 aggcaatcgt ttcctcggcg aacaaatgca tcgaaggcgt gccgggcttc ggctttgtcc
  1379461 tcgcgcgcaa atcggaactg gaggcagcga aggaccgcag ccactccttg agtctcgacg
  1379521 ttcatgcgca atgggcatac ttgaacaaaa cgggccaatg gcgcttcact ccgccgaccc
  1379581 acgtcgtcgc ggccttcctt gaagcgctgc ggctgcatcg caaggagggc ggtgttgccg
  1379641 ggcgcgggtc ccgttatgcg cagaaccgcg acataatggt ttccggcatg cgccaacttg
  1379701 gcttcgagac gttgcttggc gaccagtggc tctcgccgat catcgtgacc ttcttcagcc
  1379761 ccgcccatcc gaatttcaag ttcgagcgct tctacgagct gatgaaggcg agggggttca
  1379821 tcatctatcc cggcaagctt accgtcgtcg acagcttccg cattggctgc atcggccaga
  1379881 tggacggcca tgtgatgcgc aaggtggtcg ctggtgccgc cgaaagcctt gctgagatgg
  1379941 gggtcgattc cgccgcgccg ccggcgctgg cccttgccga gcgcgcccgc ctcgccgcct
  1380001 gacgaacatc ctcctaggag cacaacagat gaaccagatg tccaaaattt cggtaacggt
  1380061 taatggccgc cgctatccat ggccccgcgt tccggcaatt gcgatctgcc tcgacgggtg
  1380121 cgagcccgcc tatctcgatg cggcgatgga ggcgggattg atgcccgccc tcaagcgcat
  1380181 caaggaacgc ggtgccgtgc ggctggcgca cagcgtcatt ccgagcttca caaatcccaa
  1380241 caatctttcg atcgcaacgg gaactccgcc ggccgtccac gggatctgcg gcaactacct
  1380301 ttacgagcct gcgacgggcg aagaggtgat gatgaacgac ccgaagttcc ttcgcgcgcc
  1380361 gaccattttc caggccttct acgacgccgg cgcgcgggtc gcggtcgtca cggcgaagga
  1380421 taagcttcgc gcgcttctcg gaaaggggct tcgtttcgac gaagaacgcg cgatctgctt
  1380481 ctcgtctgaa aaatcggaca aggcgacgcc cgaggaacat ggcatcgaca atgcctcggg
  1380541 ctggctcggc cggccggttc cggaagtcta ttcggcagcg ctttcggaat tcgtcttcgc
  1380601 tgcgggcgtg aaactgctca aggagttcca ccccgacatc atgtatctga ccacgacgga
  1380661 ctatgttcag cacaaatacg ctcccggcgt agcggaggcc aacgcctttt acgcgatgtt
  1380721 cgatcgctac ctgtcagagc tggacggact aggagcggcc atcgtcgtca ccgctgatca
  1380781 cggcatgaag ccgaagcaca aggcggacgg ctcgcccgac gtcatctatg tccaggacct
  1380841 gctcgatgag tggttgggcg aggaagcggc ccgtgtcatc ctgccgatca ccgatccata
  1380901 tgtcgtgcac cacggcgcgc tcggatcctt cgccaccgcc tatctccccg ggcaatgcga
  1380961 ccgcggagag atcatcgatc ggctaaaggc gctcgatggc atcgacgtcg tgctggaccg
  1381021 cgaagaggca tgccgaaggt ttgagctccc ggaggatcgc atcggcgaca ttgtcctcgt
  1381081 ttcgtccgaa aacaagacac tcggcaccag cgagcaccgc cacgacctgg cggcactgga
  1381141 cgagccgttg cgctcccatg gcggcctcac agagcaggag gttcccttca tcgtcaaccg
  1381201 ggtgctgccc gatctcccgg gcgctccttg tcttcgcaac ttcgatgcgt tcttctacgc
  1381261 tgttgcggca gcggcgttga tcagtgcgga ggacgcgata tgacgaagcc ggaggtctca
  1381321 atcgccgtgc gccacgaacc gatgcgtatc gccgggcagc tgatagatac ggacgaccgc
  1381381 atagaagtgc gttatccctg gaacaacacc gtcgtcggga ccgtgcccgc cggccgggcc
  1381441 gagcacgccc gcgaagcctt tgctatcgcg gccgcctatc agccgaagct tacgcgctat
  1381501 gagcgccaga aaatcctgct gactgcggcg gaaacgcttg cgtcccgcaa ggaggagatt
  1381561 tccgacgtca tcacgctcga gctcggcatt tcgaagacgg actcacttta tgaagtgggg
  1381621 cgcgctttcg atgtcttcac gctggccggc cagatgtgca ttcatgatga cggcgagata
  1381681 ttttcctgcg acctcacacc ccacggaaag gctcgcaaga ttttcacgac gcgcgaaccc
  1381741 ctgaccgcga tctcggccat tacaccgttc aatcacccgc tgaacatggt ggcccacaaa
  1381801 gtcgccccag ccattgcaac gaacaactgt gtcgtggtga agccgacgga actcacgccg
  1381861 ataacggcac tgttgctcgc cgatattctt tacgaggccg gtttgccgcc ggagatgcta
  1381921 tccgtcgtga ccggctggcc ggcggacatc ggcatggaaa tgatcacaaa cccgtatatc
  1381981 gatcttgtaa cctttaccgg cagcgttccg gtcgggaaac tgatcgccgc caacgcgcat
  1382041 tacaagcgtc aggtgctcga acttggcggc aacgatccgc tgatcatcct caacgacctt
  1382101 tccgacgacg atcttgccag ggcggccgac cttgccgtcg ccggggcaac gaagaattcc
  1382161 ggtcagcgct gcacggccgt taaacgtatt ctctgccagg agagcgtcgc cgaccgtttc
  1382221 gtacctatgg ttctcgagcg cgcaaaacgc ctgcgcttcg gcgatccgat ggatcgttca
  1382281 accgatctcg gaaccgtcat ccatgaaaag gcggcagcgc ttttcgaaga gcgggtcctg
  1382341 agtgcggccg gggagggcgc cgacatcctt taccacccgg gtcgaagcgg tgcgctcctg
  1382401 ccgccgatcg tcgtggatcg ggtccctcac cattctgatc tcgtgctgga ggagaccttc
  1382461 ggtccgatca tcccgatcgt gcgggttccc gacgatgatg aggcaaccat tgccctgtcg
  1382521 aactccacgg ccttcggtct ctcctccggc gtctgcacca atgattatcg cagaatgcag
  1382581 aaatacattg ccgggctgaa ggtcggaacg gtcaacgtct gggaggttcc cggctatcgc
  1382641 atcgaaatgt cgcccttcgg cggtatcaag gactccggga acggctacaa ggaaggggtg
  1382701 atcgaggcga tgaaaagctt caccaacgtt aagacgtttt cgctgccttg gccgtgagga
  1382761 aatccgcttc gcgcgttata taggagcggc ctgttgccgc tcctttttat ttttgggcga
  1382821 agcaagctcg gtatagctac agctgatagt tatataaaat aaatagattt tacttatcga
  1382881 tccatccccc gcaaatttgc caggcaggcc ggatttccag gcgcgaaagt cgccaccacc
  1382941 gccgcaaaag agcttgccaa ttcgaatgcc aacaaaaggg gaattagcat gccgttctca
  1383001 aaggcctttc tgggcgccgc gaccgccttc cttctcgcat ccaccgccgc ctatgccgaa
  1383061 gccgaactta cggtctacac gtctgtcgag gcggttgacc tcgaccgtta caaggagact
  1383121 ttcgagaagg ctcaccccga catcaagatc aactgggtcc gcgactcgac aggcgtgatg
  1383181 accgccaagc tactggcgga gaaggataat ccgcaggcgg acgttgtgtg gggcgtggct
  1383241 gcgacatcgc tgctgctcct gaagtccgag ggcatgctcg aaccctatgc cccgaagaat
  1383301 gtcgaggccc tggatccgag attcgtcgat ggcgacaagc cgccgagctg ggtagggatg
  1383361 gacgcatatg tggcggctct ctgctacaac acggtggagg ccgagaagct cggcctgacg
  1383421 ccgccaacca gctggaagga tctgaccaag cccgaataca agggtcacgt cgtgatgccc
  1383481 aaccccaatt cctccggaac aggcttcctc gacgtctccg cctggcttca gacgttcggc
  1383541 gaagaggaag cctggtcctt catggacgcc ctgcacgaga acattgccgc ctatacccat
  1383601 tcgggttcca agccttgcaa gatggcagcg tccggcgaaa ccgtcatcgg cgtctccttt
  1383661 gagtttccgg gcgccaaggc gaaaacgtcg ggcgcgccga tcgacatcat ttttcccgct
  1383721 gaaggatcgg gctgggaagc agaggccacg gcgatcattg caggaacggc caatctcgag
  1383781 gcggcgaaaa cgctggtcga ctggtcgatc agcaaggaag ccaacgagat gtacaatgtc
  1383841 ggttatgcag tcgtggctta tccgggagtc gccaagccga tcgagaatct tcccgacgac
  1383901 gttgccgaga agatgatcga gaacgacttc gagtgggccg cgaacaaccg tgcccgtatt
  1383961 ctgaaggaat ggcagaagcg ttacgacgca aagtccgagc ccaagtcctg agctggtgat
  1384021 ccgtcgggaa cgctcggttc gagagcgtcc ccgtcaagcc tcatcgaatg ccgtgcggaa
  1384081 ttgtggaggc cctcagagca ttttcgtgtt cggagaaaaa cgggaatgct caggagccag
  1384141 gagcttgcgg atgaaacatg caacagcccc agcggaaccg gccatgcccg tgtccgccaa
  1384201 ccgtcagagc gaaagacgac cattcctcga aatcagcggg ctgtggaaag cctatggcga
  1384261 tttcgtcgcg ctacgagaca tagacctcca ggtgaaggag ggtgaattcg tctgtttcct
  1384321 cgggccctcg ggctgcggga aaactacgct tctgcgcgcc atcgccgggt tggacataca
  1384381 gtctcgaggc gccatccgcc aagccggaca ggatatctcg cgcctgccgc cggcacagcg
  1384441 cgactatggc atcgtcttcc agtcctacgc gctctttccg aatctcacga tcgaaaagaa
  1384501 catcgcattc ggactcgaaa atatcggccg gcctcgccgc gaaatagcct cgcgcgtctc
  1384561 cgaccttctg gacctcgtcg gcttgagcag ccaaggacgg aaatacccgg ctcaactatc
  1384621 cggcggtcag cagcagcgcg tagcgcttgc ccgcgccatg gcgatttctc ccgggctcct
  1384681 gcttctcgac gagcctctgt cggcgctcga cgcgaaggtg cgcgtccacc tgaggcatga
  1384741 gatcaaggag ctgcagcgca agcttggtgt caccacgatc atggttacgc acgaccagga
  1384801 agaagcgctg tccatggccg accgcatcgt cgtgatgaac cagggtggta tcgaacaggt
  1384861 tggaacgccg actgagatct atcgccatcc gagaacgctt ttcgtcgccg acttcatcgg
  1384921 ggagaccaac cagtttcccg caacggtcgg taagggcgcg caggtcgaaa tagggcacac
  1384981 tcggtttgcc tgtgcggaac acctgttgcc cgccggtgcg gcggtcgttg ccgcggtccg
  1385041 gccggcggat atcattccgc acggcgccga cgcccaccgg gcaaccgggc tcgaggccgt
  1385101 gggcaacgcc gacaatctaa tcgacgcaca tgtggaggat atggaatttc tcggcatgtt
  1385161 ctggcgcaca cggctctcag ccccgcgtct gaaggagacg cctctcgtgg cggatttctc
  1385221 tacgaacgcg gttcgccggc tttgcatcga gatcggcagc gccatccagg ttgaaattcc
  1385281 gcaggagcgt ctgctcctat ttgcaaaggc ctgatccgaa tgacgcttgc tgtcgatttc
  1385341 cttccgcccg gccgagccct tcgccagcag atttccgacg atgacaggct caagcgcgca
  1385401 gtcatgttcg tcgtcggcat ctatctggtt atcgcgcttg caataccgct tttcgtgatg
  1385461 ctgtcgaaat cgctttccac gtacacgttc gatcttcatc aatttgagtt ccaggtgagt
  1385521 gacgagagcg gaggagggtg gagcgaccct gttacggctg cggcgctcaa cacagccatc
  1385581 gccgcctttc ccgaaagcga tctcgaggcc ggtgccgacg gaaggctgca ggcggccaaa
  1385641 ctctttgcag atttcagttt ccgcagcccg gtcagatacc gcatccgcgg cacgagcgaa
  1385701 gaggcgcact tccttgccgg ctcgcaactg gtgcgcggga ccgagtggaa ggaatatgac
  1385761 agcaaccatt tccggcgcgt gatgctgcgg ccatcgcgct cggtcgggct ctccaacttc
  1385821 acggaatatt tttcgacgcc gtcactcgtc cgctcaatca agaattcggt gatgattgcg
  1385881 ttaatcagca cggcagtcac cctcaccgtc gccttcggcc tcgcctatgc cctgaacaga
  1385941 agccggatgc gggggaaggg ggcgttcaag ctcattgtca cgatcccgat cctcgtgccg
  1386001 tctctcttgc ccggtatcgc gctggtgtat ctgttcggca atcagggcgt cttcaaggat
  1386061 ttgctgctcg ggcattcgat ctatggtccg ctcggcatcg tcgtgggctc ggtgttcttc
  1386121 actttgccgc atgcctttct gatcatttcg acggcgctgt cggtcgccga tgcccgtcac
  1386181 tacgaggcgg caacgtcact tcgtgcaagc aggtggcgga ccttctggac cgttaccgtg
  1386241 cccggcgccc gctacggcct gatctccgcc gccttcgtcg ttttcacgct ggtcatcacc
  1386301 gatttcgggc tgcccaaggt catcggcggg caatatggca tgctcgcagt cgacatctac
  1386361 aagcaggtca tcggccagca gaatttcgaa atgggcgccg tcgtctcggt catcctgctg
  1386421 atccctgcat tcctcgcatt cgccgtcgat cgcatgacgc agcgccggca agtggcgctg
  1386481 ctctccgcac gcgcagtacc cttcgagccg aaaccacgac gcggtttcga tgcggcttgt
  1386541 ttcgccttct gctcactggt cgcaatcttc gtgctcggca tgatcggtat gtgccaggtc
  1386601 gcggcgctcg tgaaattctg gccttacgat ctcagcctgt cgctgcgcaa ctatgccttc
  1386661 gacctcatgg atggcggcgg ctgggatgcc tattacaatt cgatccggct cgctctcatg
  1386721 actgctgtca ttggatcgct gatcgtgttc accggtgcct atatggtcga aaaaaccaag
  1386781 ggtttcggct tgggccgagg tgcattccac atgcttgcca tgttgcccat ggccgtaccg
  1386841 ggcatggttc tgggtcttgc ctacatcttc ttcttcaaca acccgggaaa cccgttgcac
  1386901 ggtatctacg gcacgatggc catcctggta ttatgcaccg tcacgcattt ctataccgtc
  1386961 gcccatctga ccgccctcac ggcgctcaag cagttggatc cggaattcga ggccgtggcc
  1387021 gactcattga agataccgtt ctacaagctc ttcttccggg tcaccttgcc ggtgtgcctg
  1387081 ccggccctgc tcgagatcgc gatctatctc ttcgtcaacg cgatgacgac tgtctcggcg
  1387141 gtcgtgttcc tctatgccac ggatacgaag cttgcttcgg tagcgatcct caacatggac
  1387201 gatgcaggcg acatagcccc ggcggccgcg atgggcatga tgatctttta taccaacgtg
  1387261 gcggcaaaac tgctccacgc agtcgtagcg cggctgcttc ttgcccgcac acagggctgg
  1387321 cggcaggtgg cgcagaccgc ggtgccagcg tgagtgtgga caccctattc ccgctgcttt
  1387381 caccagcttc gacacggtga agttgacgcc gcatcgcgct cgcgcgcctg tttcgaacag
  1387441 tctttcaccg cgatctgctg cttgccatgc gactgtccca tcgccgcacc gacgtggttc
  1387501 gcataattgt ctctgctgtg cgggtcgatg gcggcgaccg gagcggcaag gatcaagccg
  1387561 gccgcgctgc cggccgcagc ggctgctccc gtcgttcccg caatgagatg gtccccgagg
  1387621 cccatccggc tgtcggtcaa cggctgacct tcggagatgc gtgcaccgat gagccggacg
  1387681 acttccgggg attctgcgaa cttgccgtga tgcatgccgt cgccggcctt caccttggtc
  1387741 agatcgataa cggtgatctc gttgtccgcc agttcctgct tgtagggatc ggcctccggg
  1387801 tcgatcgaac caagccgggg aatgtcgccc cagaccctgc gagagaaggc tagcgcccgg
  1387861 tcgtcgcggg atacaaacag ggtaaaccgc ggatgctgcc tgcccatgtc ctcgatttgc
  1387921 gaacggaaga cgtcgacatc gacatccgga gccgcaagca tcacgttctt gaatttttcc
  1387981 ggcaggccgt cattgcggat ggccatctgg cgaagcgcct cgagcgtgag ccagttcccc
  1388041 atggaatgcg cgaggatcga tacctccttc acctctttat ccgcggccag atactggaaa
  1388101 agcgattcga gtgcgttgcg ggtgtagttg gtgctttcgc ggtcgtagcc ataggcaagc
  1388161 aggctgcccc gcgacggcca tgtcaccagg acaggggcgc tgtggacgcc ggaatcatgg
  1388221 acgatctgag cgaagcggta gacggagtcc tcgaagcggt tgttgaagcc gtggatgaac
  1388281 acgagcacac tgcggtcggg gcttttccgg actgtggtgt tgagccagtc cttggctcca
  1388341 tccctggtca ggtcgtccgc cttcaaagtc gcgaaatcgg tggctggatt ggacggcaat
  1388401 ttcttcggcc aggcaacctc tccggccttg cggacaggcg ggatcgagac ggtgatgttc
  1388461 gcgaaggccg gtgcgcgggc tcgttctccc gtaaacatct ctccggccac ctccgaacgg
  1388521 ccgcgggtgg tggtgatcag catgtcgacc cggctcgctg tgggcgcgct gtcggcgaca
  1388581 ggcgtcagca cgcctttggg atgcccgccg cagccggaaa gagcggcaat tgccaggcaa
  1388641 aggatcatcc gctgaaggcg aaccacagga actgatgagg cgacaagaaa atcgcggctg
  1388701 cgtcgattgg ccaacacgta ctccgatctg cggaaaatgc gaatttatca atgatagact
  1388761 ccgaaagtgc agcgcccgcg gtctgccgag ccgcgttcgc ggcggcgaca ggcgtgagcg
  1388821 accggccacc ccggcatcgg cgaaactcta tgtgcggacg gagcgaaacg ctcgtaacat
  1388881 cgggtatgct ctgttgcaca agccgttgaa gatccttcgt gcggcgaggc tttcaaaggg
  1388941 ttcagcgacg gtcggtcaca gcggatttca gaagctcggc ttcgatgccg gccgcatccg
  1389001 gcacgggcac tccagccttg cgaagcgagg cgatcatgcg aatgctgtct ttcggctgaa
  1389061 tgttgcgctt ccggttctcg ttgatgatgt cgcggatgta ttccggtcgt atcttcgtga
  1389121 agatcgttcc ctcgcgccgg gcatcgtcga tcagtccagc ctcggcatag attgcggccg
  1389181 ctacgatatg gaacagagga aacttctgca ggtcggcttt tcggatcagg ctcaccgcct
  1389241 ttgcatgatc gtcaagcatg taggcggcaa gcgcgcgtgt cccgtgataa taggccgcac
  1389301 cgccaggatt cagcgcaagc gccctgtcga gcaaatccgc gccccgcttc cattgcccgc
  1389361 acagtgcaag ccgagttccg aactctgcca gcagttccgt atcgttcgga ttggtcgcca
  1389421 gtgcctcttc gccggcctcc agcgcctccg caagttgctg attgaagaac aacgcggtca
  1389481 ttagggattg aagcgcgcgc gtattgtccg gttcaagctc gattgcacgg cgggcagcgt
  1389541 ggagcgcccg ttccattggc tctcgctgag ccgggttcag gttatatcgg aagcggtctt
  1389601 catcgagata ggcgatggac aacatggccc atgccgtcgc ataggccggg tagcgggcga
  1389661 cggcgctttc caggcaggcg cgtgcactca gatgggcttc cggactgagt tcggcgcgat
  1389721 aggcataaaa tcgaagggtg cagtcgtaga cgccaaggtc gtccggcgga ggcttggccg
  1389781 tcacagcctg cgcaatgatg ccgtagggct gggcaacggc cgtggcgacc ttgcttgcaa
  1389841 cgtcggactg gatggcgaaa agttctcgcg tggtcagatc gtcatcgtaa ttctgcgacc
  1389901 agagtatcgc gccgtcagac gtgtcgacaa gccgtgccgt cacccgaacc cgtgggcctg
  1389961 acaccctgac gccgccagcg agcaggtagc gagcgccgag cccgccacgc acctcggacg
  1390021 cctgcacttc cggtgcaagc gatttcgacg tttcccgccc gaacaccctg atttctttga
  1390081 accggggcag cgcggtcagc agttcctccg tcaatccgac ggtatagagc tcggactgtg
  1390141 ggccatcacc cagattggcg aagggcgcta ttaccagggt cggctcgtca ggcaccgcgc
  1390201 tgaagccgga ctgtctcgta ccggctatga aacggtcggt tgcccaatac gtcagcaccg
  1390261 cagtaattac gacaccgacg aggccggcaa ggatcggtaa tggggtccgc agcctgcctt
  1390321 gcgccggccg ctcgtcggag ttttctgccg cggcttcctt gcgacccgtg accgccgcat
  1390381 cgttccatgc gaaagacgga gcatagccgc ctttcggaat atctatcctg atgggatcgc
  1390441 cctgtccggc gaccagataa tagcgctcga gcgtgcgtct caggcgcccc gcttcgatgc
  1390501 ggacaactgg atcgtcctgg gtgaaggtgt cgctgcgctt gaatacctcg atcgcgacgg
  1390561 tatagccctt caggcgatgt gcacggccag ctatcgcttc ttctacgacg aaggtgagaa
  1390621 acgcggcgcc acgcccggct ttcggaaatt caggactgga aatgacccgt gcaagctgcg
  1390681 cacgaatctc gtccggcccc ggcaacggat agggcagggg ctccgcgccc ccggatccgt
  1390741 gtgtcacagc ggtgaccatt acttgctccc ctcacgcccg gaggcgcagc aatcgcagat
  1390801 tttattggcg tgcccgcgtg taacctacgc cacgaagacc gcaccgtcca gaaagatacc
  1390861 aagccttcat gaacgttatt gttgagttgg atcgattcac tactgtattc actggtacgt
  1390921 atcgaggcgt gtagattact gttacatact tgttttctgg tgctgcaggt tcaacatccc
  1390981 gacttccaga acccaccggg cgcgatgata ggaacagaga cattctctat ctgtgcgtgc
  1391041 tcaaccactc atcgcaagcc ggaaggaagt ccgagatgct cacgaaacgc gatctgcttc
  1391101 acgctgctgc gatagccgcc gcggtggccg ccacggcggc gaggtccacc ccagcaattg
  1391161 cccaggacaa agccggatgg cccagcgtgc tggaggccaa ggatattgcc gaggaagggc
  1391221 tcatctatgg cttgccgctg gtgatgaatt acgcggtcat gcaggagttc gcagtcgaca
  1391281 gaaactcggg gcagttcaag gcacctttca acgaaatcaa caacatgcac catgtcgcga
  1391341 cccccgcgga cactgcaatc ataacgccga acagcgatac cccttactcg tttgtgtggc
  1391401 tggatttgcg cgccgagccg atggttctct cggttccggc gatcgataag gaccgatact
  1391461 attcgatcca gctcatcgac ggcaacacct ataacttcgg ctatatcggc acgcgcgcca
  1391521 cgggcaccga gccgggcgac tatctggtgg tcggccccga ctggaagggt gaaacgcccg
  1391581 ccggtatcaa gaaggtcttc agatcgacga cgccgttcac gtttaccgct atccgcacgc
  1391641 agctcttcaa ccgcaacgac atgccgaggg tcgagaaaat tcaggctggc tacaccgcgc
  1391701 agcctctctc cgctttcctg aaacaaccgg ctccgcccgc atcgccgaaa atcgacttcc
  1391761 ttccagccac cactgcaggg atcaaggaca acttcttccg atatctcgat gcgtccctgc
  1391821 aattcgttcc tgagacgtca agggacaagg ccatccgcgc gagactcgct aagattggca
  1391881 ttggtccggg aaagaccttc gagttcgagg atctgtcgct cgaacacaag gacgcaattc
  1391941 gcgtggccat gaagcagggc aatgacaaag tcgacaaatg gctgaccaac ggaaacaaaa
  1392001 atatcaacgg ctggaacatc ggctcgttct tcggtgacga agccttcttc aacggtgatt
  1392061 ggatgatgcg ggccggggct gccaagggcg gtctctatgg aaatgatgcc gttgaagcca
  1392121 tgtaccccta cacccgaacg gacacgaccg gcgagccgct cgacggcagc aagcacaagt
  1392181 acacaatcac cttcgcaccc ggccagttgc ctccggtaaa tgcgttctgg tccgtcacga
  1392241 tgtacgacgg caagagccag ttcctggtca agaacccgat cgatcgctac ctcatcaact
  1392301 ctccgatgtt gccggggatg aaaagggcgc cggatggttc gctgacgctg tacattcaaa
  1392361 aggacagccc cggtgcggac aaggaggcaa attggcttcc agccccggat ggcacgattt
  1392421 atctcgtgat gcgcctgtac tggccgaagc ctacgccacc ctcgattttg ccggcgggcg
  1392481 aggggacatg gcagccgccc ggcgtgaaac gggtctcgta gaggcgcaca tgaattcctg
  1392541 agatgcccag gagcgccgaa gcaccgtcgg acagccataa gtcccgcata ttctgtgcgg
  1392601 caggttaggc cggcgcgcct cgcgacggaa aggtgtagcg gccctagtcg cgctgcctcc
  1392661 caaaaccgga gcgttcgggc atggtgcgct accgacggaa aaccgccggg ccaccgtggc
  1392721 ccggcaagcg tgggagccat atcatgggat acgacgttgc tttcacgaaa cgatgctttc
  1392781 cggcccgtgt cggactgatc gacgaactcg ccgcccgtaa cgaaagcttt cgcgatctct
  1392841 gttatgactt cgccaccgcg gaggaagtga gactggcatg ggagacagcg tccggacccg
  1392901 agaaggacga gcgtcacgct gagtctgtgg aacttgtaga ctgccttcgg accgagatcg
  1392961 aggcggcgct cgatgacgcc gccgtcgtgc cgtttcagcg ccggcggact taacgagccg
  1393021 acaagggcag ggccctgcat catcgaacgc attcccgaga ttcctcttca aagccggcga
  1393081 ccagaggttt gtaacttttt gactttccgt gcgttttgtc gagcgtagtg cacaatgttg
  1393141 gaccgtgatt tgaccgacac cgggtggagg aagatcaatg acgatgaatg actggcgcgc
  1393201 cgacctgcgc ctcgggctcg aaaacctggt cgatgccgcg gtcgttgccg gtgcgcacca
  1393261 acgggatgtt tacgcagcca tccttgacga agtcgaacgc cttcggctcg cctacgagcg
  1393321 agatcccgat ccggccgacg atctcagtga acagatcgtc gaagaaccgt ccaacaactg
  1393381 gcctgcggcc gagcaggact gagtcggaac tcgggatggc cgtgggtctg ttcctgttcc
  1393441 tgccggcatt cggtcagcgt caaacaagtt ccataacata cgttatgcga tgaatccatg
  1393501 tagccgggta cattctattt ccaagtgcga catgccaata aaaacaaagg cttcgccctg
  1393561 gagatttttg gatgtcgcag tgctatttgc agctcaccct tcccgatcgc cgacgcgtgc
  1393621 atcagcttct cgaacgcaag gtgccgattg ctgagatcgc ccgccaactc ggtcggcatc
  1393681 gatcgacgat ctatcgtgaa ctgaagcgca atacctttca tgatgccgag tttccggaat
  1393741 acagcggcta ttacagcggt attgccaacg acatctcgaa ggagcgtcgg cgacggctgc
  1393801 gcaagctcag ccgccacgcg caattacgcg aactggtcat cgagcagctg aaggcacttt
  1393861 ggtcgccgga gcagatcgcc ggccgtctgc ttgccgatgg tgtgagcgcc gtccgcgtct
  1393921 gcaccgagac gatctatcgc ttcatctata gcaaggaaga ttatgcgctg gagctctatc
  1393981 agcatctgcc ggaaggccgt cgtaagcgcc gcccacgccg ctcccgcaaa ccccgtgacg
  1394041 gctcgatccc gttggactgc aggatcagcc aacgccctga tttcattgcc gatcgctctc
  1394101 agttcggcca ctgggagggt gatctcctga tcttccggcg cgaccttggt gaagccaatg
  1394161 tcacctcgct ggtcgagcgc aagagccgct acacggtgat gatcaagaat ggcagccgtc
  1394221 actctcgtcc gctcatcgac aagatcatcg atgccttctc accgctaccc gcctttgccc
  1394281 ggcagagctt caccttcgac cgtggtaccg agtttcgcgg tttcaaggct ttggaagatg
  1394341 gactcggcgc caggagctgg ttttgcgatc cgaattcacc gtggcagaaa ggcgcggtcg
  1394401 agaacaccaa caagcgcatc cgtcgctttg tgccgagcga tacggacctg tccgccgtca
  1394461 accagccgca actggtcgcc ctcgcccacc atctcaattc actgcccagg aagtgccttg
  1394521 gttaccgcac gcccgccgag gtcttcatgg cccatttgcg cgactgcggg taatccccta
  1394581 ccctccaccc gtcattgttg cacttggatt agattctcca ccgcaaagtt aaagtgtcct
  1394641 gtttctgcaa tgtaagaatg tcactctccc cgggtttaga tgacctggga gattgcggat
  1394701 gggattgatt gcgatgagcg agcgtgatct gcagcggatt gaggttttgt cgaaggtcat
  1394761 cgatggtcgg atgacgctgg taacggccgc tcatgttctg gggttaagca cgcgccaggt
  1394821 gcgtcgactg ctggagcgga tccggacgga tggtgccgca tcgatccggc acaaggcgat
  1394881 cggtcggcca tcgaacaacc ggatcagcga cggcgttcgg gattatgcag tgacgctggt
  1394941 tcgcgaacgc tatgccgact ttggtccgac gctagcggcg gagaagcttg ccgagcgcga
  1395001 tggcttgcgg gtgtcgcgcg agaccttgcg caaatggatg tcggaggccg gactttggct
  1395061 gtcgcgcaag cagcggcgca ccttccacca gccacgattg cgacgcgagg cctatggcga
  1395121 gctggtgcag atcgatggat cggagcaccg ctggttcgag gatcgcggtg atccatgctc
  1395181 gctgctggtg ttcatcgatg atgcgaccgg caagctgatg cagttgcgtt tcgtgcgctc
  1395241 ggaaagtgcg ttcagctatt tcgaggcgct ggagctttat ctcaaaaatc atggtgctcc
  1395301 ggtcgccttc tattccgaca agcattccgt gttccgggtg gcgaagaaag acgccaaggg
  1395361 cggccagggc atgacccagt tcgggcgtgc gctttcagag ctaaacattg agattctttg
  1395421 tgcaaattcg agccaggcga agggtcgggt cgagcggatg aaccggacgc tgcaggaccg
  1395481 tttgattaag gacctgcgcc tggagggcat ctgtggcatg gacgacggca acgccttcct
  1395541 gcctcggttc atggagggct ataaccggca gtttgccatt acccctgccc gacctgatga
  1395601 tctgcaccgg tcgctgaatc ttgccccgga tcggctcaag gagatcctgt gcaaacgcga
  1395661 gcagcgctac gtcggtgcgc agctgacgtt ttcgttcgag cgccagcgga tcatgcttga
  1395721 ggagaccgag gtgacgcgcg ggctggtcgg tcgctatgtc gagacctacg cctatgccga
  1395781 cggccggctc gatgtgcggt ggaaaggcca ttgcctgccc taccgggtat tcgacaagga
  1395841 ccagcgggtg acgcatgcgg cgatcaccga gaacaagcgg ctcggtgatg tcctggccta
  1395901 catcaaggcg cgccaggacg agcggccggc gccgaaggtg aagaccaaca gcgagaagat
  1395961 cggctaccga ccgcgtggcc gcaagccggg caagcggacg gatttcacca acgatccagc
  1396021 ggtcattgcc cgacggcgac aagcgctctc tgagctcgat gcggcggaat gactggctgc
  1396081 tgcaactgtc aaagctaaag ccgatgggtg cgtctcaccc gccccctccc ttcccttgca
  1396141 acccgatcca gccggtccgg tcgggggctt ggctcagtgc cagtggggat gtcgcgtgtc
  1396201 gcatttctaa atggttggtg aggcacccaa agtgacattt caactttgcg ccggagcgga
  1396261 catttcaacc ttgccgccac acccatgtag ccgggtacat tctatttcca agtgcgacat
  1396321 tccaataaat aattcctgcc atcctcgtcg agccgacctg gcgtatggcg cggcttcggg
  1396381 aaggccggtg tcgcccggcg tcagacatcc ttgagaagtc gaagcgcatc atagatcgca
  1396441 gcatgcgtgt tgcgcgccgc gaccgcatct ccgatgcgga aaagctggaa ctggccgtcg
  1396501 gggttgcgga cgacggattg cggttcgccg gcaatcagtc gctcatggtc gatctcaccc
  1396561 cggttgctgg aaaagggctt cagctcgaaa tagaggtcat cgagcggaat ggtcccgtgg
  1396621 ttgacaacca cctggtcgaa ggtctgctgc cgggcgatac cgccgtaatc gctgcccaca
  1396681 tgggcaacca gttgattgcc gctcctctcg accgcctcga gacggtaggt gacggtaaag
  1396741 gtcacatcca gcttctgcag ggaacgcatg tagggcacca ggttcattgc catgacctca
  1396801 ggcgcgaagg agcgatccgg ggtcatgatt tcgacccttg caccggcact ggcgagaaac
  1396861 tcggcggcct gcagggctgc atggtccccg gcatcgtcga agatcaagac attggtaccc
  1396921 ggcttgacgt cgccggaaat aatgtcccag gcggacacga cgagctcgtt gccctttgaa
  1396981 agtacttccg tgtgcggaag cccacctgtg gcgatgatga cgacgtcggg tcgttccgcc
  1397041 cggatggtct ccgcttccgc ccatgtgttg aaatgaaagg tgacgccgag tttctcgcat
  1397101 tggcccatgc gccaatcgat aatgctgatc atttcccggc ggcgcggact ctgcgcggtc
  1397161 aggcgaacct ggccgcccgg atcgcttgcc gcctcgaaaa cgacgacttc atgaccacgc
  1397221 tcaccggcta cacgcgcggc ttccagaccg gctggcccgg tgccgacgat gaccaccttc
  1397281 ctgcggcggt ctgccttggc gatgctatgc ggcatcgtca actcccgccc ggtcgccgca
  1397341 ttgtggatgc agtaggccgc cccgccctga tagatgcggt cgagacagta gttcgcgccg
  1397401 acgcaggggc gaatatcatc ctcccgcttt tcgacgatct tgcgaacgag gtgcgggtcg
  1397461 gtcatgtggg cgcgcgtcat cccgaccatg tcgatcttgc cggaggcgat cgcgtggcgg
  1397521 gcagtcgcga cgtcggggat tttcgcggca tggaacgttg gaaagtccgt ggccgctcgg
  1397581 atctctcctg cgaaatcgag atgcggcgaa ttggccatgc cctggatggg gatcacgtcg
  1397641 gtcaggccgg cgtccgtatc gatatggccc ctgatcacgt tcaggtaatc gataagcccg
  1397701 ctttccttca ggcgttttga gatttctagg ccctccgcct tgcccgtccc gccgggaaga
  1397761 cattcgtcgg ccgtataacg cacgcccagg atgaaatcgt ctccaacgcg cgttcggatc
  1397821 gccctcagca cgtcgaaaca gaagcgcata cggttgtcga gcgacccgcc ataaggcccg
  1397881 tcgagttcgt tggtcagcgg cgacgcgaac tggtcgagca ggtggccgta tgcctccagc
  1397941 tcaacgccat ccataccgcc ggccttcatg cgttcggccg cgtcggcaaa atccttgatt
  1398001 atcctctcga tgtcccagtc ttcgatcttt tttggaaagg cgcggtgcga ggcttcccgg
  1398061 agatgcgagg gggcgacgac cggaagccaa tcccccttgt cccaacgcgt ccggcggccg
  1398121 agatgggtaa gctgaatcat gatcgccgca ccctgctcgt gcacagcgtc ggtcatttcc
  1398181 ctgatccacg gcacgatctc gtccttatag gcgagcagat tgttgaacac cggaggactg
  1398241 tctctcgaga tggccgcgga gcccgcagtc atcgtcagtg ccaccccccc tttcgcgcgc
  1398301 tcaacggtgt aggcgcgata acgcgccttc ggcatgccat cctccggata ggcgggctca
  1398361 tgcgcggtta cgatgatgcg attgcggagg gtcagatgct tgagctgata gggttgcaaa
  1398421 aggggatcat tcgacatctg ccaggctccg gttaaatacg tccgcaagaa gtagcccgga
  1398481 atgtacactt gtgtcaagaa agagaccata aatgtcacct gagttgacat gcatgtacat
  1398541 tttgcttgcg atacgtccct ccgtttgtta ggaagcaatt atggagcaga ccatgaacga
  1398601 tagtggttgg cgtggttcac cggatgtttg gctcggggcg gcttacgagt ctcttctgga
  1398661 ggcgggtgtc gatgcggtga agatccagcc gctggcaaag aagctcaatc tttcgcggac
  1398721 aagcttctac tggttcttca aagaccggga agaattgctc gatgcgctcg tcatacgatg
  1398781 gcgtgagaaa aacaccggca atctcatcaa gcaggccgaa gcttacgccg agacggtcgc
  1398841 cgaggcgatg ctgaacgttt tcgattgctg gctggatagc agcctgttcg actcgcagtt
  1398901 cgagtttgcc gtgagaagct gggccattca gtcgcccgaa atactcgcag aggtccagag
  1398961 agcagatcag cagcggcttg aggcactcac gcgcatgttc ctgcgatttg ggcagaacga
  1399021 ggcccgagcc gatgtgcgcg cgcgcacgat ctatctcgta cagatcggct acatttctat
  1399081 gcagacgaag gaggacacca ccgtccgcat gaagcgcatc ccggaatatg tggaaatctt
  1399141 cactggacaa gcgccggagc agagagagct cgaccgcttt ttcgccaggc atggctactc
  1399201 ggacagcaaa aaaggcgctt gaggatgggc gaggcattgc cttgctgaag ggattatagc
  1399261 cggtctcagg atatcggctg gtgtgagact gtgttccagg atctgatcga gcgggtaagc
  1399321 ggcatcctgc tcctttaata atgtgccgca gcaagaaatg ggaacagcct aatgaacaaa
  1399381 ctgcttgcgt ctacatgtct catgctttgc ctcacggcgg gagcatcggc gtcgaatgct
  1399441 gccgaatgtg ggagcgtcac catcgccagc atgaactggc agagtgccga ggtcctctcg
  1399501 aacctggaca agttcattct caacgaaggt tacgggtgca gcgccgagat aacgattggc
  1399561 gataccgtgc cgacaattac ctccatggcg gagaaaggtc agcccgatat agcacccgaa
  1399621 gcctggatcg acctcctgcc cgacgtcgtc aagaaggggc aggacgacgg tcgtatcgtc
  1399681 acggtcggtt ccccgttgcc ggatggcggc gtgcagggct ggtggattcc gaagtatctt
  1399741 gccgacgccc acccggatat caaaacaatc ggcgacgctc tgaagcaccc cgagctcttc
  1399801 cccgcccccg aggattcgag caagggcgct ctgctgaacg gaccgcaggg ctggggcggc
  1399861 acagtcgtga cgacgcagct tttcaacgcg ttcgacggcg agaaagccgg attcaccctg
  1399921 atcgataccg gctctgccgc cggcctggat ggcgccatcg ccaaggcgta tgagcgcaag
  1399981 gaaggtcttt ttacctatta ctggtccccg actgccctcc tcggcaaata cgagatggtc
  1400041 aagctcgagc ccggcgttcc gcacgactcg gccgagtgga agcgctgcaa cacggtagcg
  1400101 gattgccccg atcccaaacc gaacgcatgg cccgtcgaca cgatcgtgac gctggtcgcc
  1400161 aagccctttt ccgagcgggt cggccccgag gtgatggatt atctgaccaa gaggtcctgg
  1400221 agcaacgaga ccgtcagcaa gttgatggcc tggatgaccg acaatcaggc aagcggtgaa
  1400281 gaaggtgcga agcgcttcct cgaagagaac caagacatgt ggtcgaagtg ggtctcgccc
  1400341 gaggccgcgg agaagatcaa agccgcgctc tgaactttga ataaaccact tccggaggca
  1400401 gtttcaccct ctcctgcagt gctccagact aagcagtgga tgcggcttgc accggtcgcc
  1400461 gcattcactg ccgaggacaa gaaatcaagg cgcggaacaa gttgggccgg ctgtccattt
  1400521 gatgttcatg aagatcatcg tttttgccgc agcatccctg acgatggggc tcactgccac
  1400581 cgccctcgcc gaggaacttc aaccggaagc gataaacact gctccgatcg cgtccattgc
  1400641 accggaacgg ccgccgaagg aatcgcctca cccggatccc gccatcgtcc atctccaggt
  1400701 tcttctggat agggcgggct cgtctcccgg agtgatagac ggctactatg gcgagaacgt
  1400761 cactaaggcg attgccggtt tcgaggccat gcagaagctt cccaccgatg ggaagttgga
  1400821 tcccgaggtg gtgagccggc tttcggagga caagcccgct atacaatcct atgtcatcac
  1400881 cgaagaggac accaaggatc tcgtctctga cattcccaac gattactctg aacaagcgga
  1400941 aatggacaat ctcggatata agagcgtcga agagagactg tccgagcgct ttcacatgga
  1401001 cgtcgacctc ctcaagactt tgaacccgaa ttcgtcgttc gataccggag aaacggtgtg
  1401061 ggttgcgatg cccggcgctc cgaaggaggg cgtggtcaag aggatagaag tgcgcaaacg
  1401121 atcgggccag gtcctggcat tcgccgaaga cggtgcgccg atcgccgtgt atcccgcctc
  1401181 catcggcagc gaagcgtcac cctcgccgag cggcagacac aaggtaaaag gcgtcgctcg
  1401241 gatgccccca tacgtctacg atccggaagt caacttccag caggccgaca acaacaagcc
  1401301 cctgacgctg cccaaaggtc cgaacaatcc ggttggaacc gtgtggatcg atctgacgaa
  1401361 gcctacctac ggcattcacg gcacgcccga gccgtccctc atcgacaagg ctcagtcgca
  1401421 cggatgcgtc cgcctgacca actgggacgc agaggaactt gccgagatgg tcaaaccggg
  1401481 ggtgatcacc gagttcacgg actgaaccgt ccacgacacc ggcccccgga agtaaaaccc
  1401541 tgccggttcg ccagcatttg gcacccggag cgggccttcg tcagatagtt gaagcggcgg
  1401601 taaaaaccgc cagctgagcc tcaaatgcac gtttgtatcc gggccgggct tcgccgcggg
  1401661 cgacgtatgc agcgaggttc ggatagtcct ccagcatgcc cgatcctttc gacctgagaa
  1401721 gcaccgacac catcaggagg tcgccggcgc tgaaaagacc atcgagccat tcggcctcgc
  1401781 caagccggtc ggaaagcgca ccgagccgct ttccgatgct gtccttgagg aaccgcagac
  1401841 gctgttcgta ccagggttcg tcgcgctcga atatcctggc gaggtcgtga tcaaagatcg
  1401901 gcggttccac cgtgttgagt gcggcgaaca tccatgtgat ggcgcgcgct ctggcatttg
  1401961 ggtcgtccgg cagcaggccc gcatggtttt ctgcgatatg caagacgatt gcccccgact
  1402021 cgaacaacgc caggtcgcct tcttcatagg tcggaatctg cccgaaagga tgaagcgcga
  1402081 aatgggctgg ttgcttcatc tcctcgaagg aaagaagacg aacgtcgtaa ggctgaccca
  1402141 cttcttcgag tgcccagcga acgcgcatgt cgcgggccag tcccttcccg cgatcgggcg
  1402201 accgttcaaa ggcggtaatc gtgatagtca tcgctgttct ccatagctcg tctgtttcga
  1402261 agacgagtgg ctgaaggcga ttccgacagc catgcccgag atgtcctggt atcccggtct
  1402321 agtgcgcacc cggctgacgt ttggccgccg aggctaccgc gacgaatgcc gctataccga
  1402381 tcgcacccag gcaggcattg gccatcaggg cgacattggt gccgaaccgt tccatcagga
  1402441 cggaaaagac aaagggggcc atggcggctg cagccagccg agcggcggcc atccggcccg
  1402501 taatggctcc atagccggag gatccgaaca gccagagcgg aagcgagccc tgcgcaatgc
  1402561 tgttgatgcc cgatccaaga ccgaggcaaa tcgcgaaagc cacggccccg ggtagccatg
  1402621 tcccggaaag accgagtacg acgacaccgg cgacgatcag cacggccgat agcgtcgcga
  1402681 gcatgggcgg cagcaggtta gcgcctagcg tcatgttgat cagcctgctc agaacttgag
  1402741 acggtccgaa cagcgaccct atcacgacgg ctgccggccc gaacccgatt gctccgagca
  1402801 tcggtaccat atgtgtcaat attgctgaaa gggtgaaccc ctggagggca aaggcccatg
  1402861 aaacaaggag catgccccgc cgcctcaccc gtgttggaag cgctccggcg atagcctctc
  1402921 catcgatgcg agaacgttcg accgccccgt gcttcctgct tcgcagaatc cagtaatgca
  1402981 gtggaagaca gatgagcagg ttcaaccccg cataggcgac gtagatctca cgccatgaga
  1403041 gaagctcact caggttcacg gcaatcggcc agaagatcgt cgaggcgaaa cccccgatca
  1403101 gcgtcagata ggtgatactg cgcgaggcca tcttggggcg gacttccacg agcgtcgcaa
  1403161 aggctgcctg atattgcacc atgccggacg ccacctccaa aagaacgatg gctatggcga
  1403221 acaccggcat cgaaggagac catgcgcaca ataaaagcgc cacggcggag acggccgaac
  1403281 caaaagtcat gatcgtcgcg gcaccgaacc gatccatcca accgcccatg atcggagccg
  1403341 aaaggccgcc caccagcaac gaagcggaga acacggcaaa cacttgctcg acagtctggc
  1403401 caaggtcgcg cgccattccg ggcgcaagga tgctgaagct gtagtaaagc gttccgtagc
  1403461 cgacgatctg ggtgagcccg agtgcggcga cgatgcctgc ggggattccg gacttcattc
  1403521 agagggtccc gctttcatcc gaggctggcg atgtcgaacg acacgacgcc cgttcattca
  1403581 gtgatgcccg cacgctgggg tgcccgacgc agcagtcctc catcaggaat gtcacgaggt
  1403641 ccgcaagagc gtcgtagcgg gcgctgtaaa cgatcgaacg tgattcgcgc ctctgcgcaa
  1403701 ccaatccggc cctctccagt tccttcaggt ggaacgatac attcgaggga gagacaccca
  1403761 ccttctcggc aatcgcaccc gcggccatgc cgcccggacc cgttacgacg agcgttctga
  1403821 cgatcccaag tcgggtctcc tgcgacaggg cggcaaagga cagacgggca cgcggctcat
  1403881 ccatgtttca atgatcctaa aacaattcaa acgtctacta gccgaacttg cagcgctcgg
  1403941 caagtccgag ggagatcgcc gtttccctgc atcaagtcca gatcggcgca aaccatggaa
  1404001 cgatccgcgt gccgatcggt tttcacacat ctggttagag ataacggaga ctacaatgaa
  1404061 agtgatcgcc acagttctga cagccatttc gatcgccggc ctcgtgtccg gtacagccac
  1404121 ggccgcctgc aaggatggga cttctacgga caccaccgcc tccatcaatg ccgaaaagcc
  1404181 ggggatagcc aaggacggga ccactgcccc gcttgagacc gagaataatg ccgccagcaa
  1404241 ggacggcgag accatgccat tggcaaacca gcagggcgga ggcgacaaga acctcgccac
  1404301 gtcgcagcag gacgcagaag cgcagcagac gggtgagcag gcagcagccg cgaaagcgga
  1404361 tgattgcgtt gtagaatagg tagcggccac aataggtcac tgataggcca aggcaacgta
  1404421 acggagggcc gcgttctctc cctcgcccca tctcttgaca gagatcagcg acgcgtctgc
  1404481 ggcccggggg aagtcttttg agccaaggac ttggtttggc tggattcccg cgacgagcac
  1404541 aggagtaatg gcgttgggag cgggcgcgga tcgcttctcg gcgcctctgc tcgggaggaa
  1404601 aacgtcagcc cggatgcctg tgaatgggat cgacccaata gacctcctcc ggcttttcca
  1404661 ccggttccac atcggtgatg ttgaccacca ccgcctcatt gtcagaccgc acgagcacgc
  1404721 attcgagcac gtcggcggga tcggcattga tttcctggtg cggcacaaaa ggtggtacga
  1404781 agatgaagtc gcccggcccg gcttccgcga catattcaag cctatcgccc cagcgcatgc
  1404841 gcgccttgcc gcgaacgacg aagatcacgc tttcaagcgg cccatggtga tgcacgcctg
  1404901 tcttggcatt cggctggatc gccaccgttc cggcccagat tttctgggcg ccgacacggg
  1404961 cgtggttgat ggcggcctgc cgatacatgc ccggtgtctg ggccgtgttg tcatcgagtt
  1405021 ggtccccttt gatcacgcga acaccgttat gcttccaccg atcctcccca tgatcgtgat
  1405081 gttcgggatg ttgaagatga tccgacattc tgcgtctccg tttttcgcaa ctggaagctt
  1405141 ggtgtatttc aacctggact accacggaaa cctacccgcg attcaccgtg tagagcacca
  1405201 ttggttcgct cactccgcgc aatgaaaact cgccgagcgg cgaaagcccc tcgcgtgacg
  1405261 ccggtctgca gacgttgacg aagtcggccg agaccagagc gtcgttattg gtggtcttgc
  1405321 agatcgtgca gatgcggctg acttcgttga cggccggtcc gacgacggtg aaatcgagcc
  1405381 ggttccggct ccctatattg ccgtagaaga ccgtacctaa gtggaggctg acataaaggc
  1405441 cggtggaagg ctcgccccgc gcgccgcgcc gccggttgag atgatcgagg tctctgcgca
  1405501 attcgcgctc ggtctgaagc gcgcgggaag cggcggccgt cagatcgggc cctttgaaga
  1405561 tagcaagcac gccgtcgccg atcagcttca gcacgtttcc gccgttgcga tggagcgcgc
  1405621 cgatgacaac cgaggaatag tcgttgagga gcggaatgat ctgttccggc cgggcggcat
  1405681 ccatgatggc cgtgtagtcc ttcaggtcgg acagccagat gatcgcgtcg atcgtctcgg
  1405741 cctgcccgcg cgcgacctgt ccgtcaatga cgcggctggc cgcatcctgg ccgagataga
  1405801 cgcgcgccag agttttgacg attcgaatgc tgccgacgct tttcaacgcg agcgcgagcg
  1405861 tcggcagaag ccggcgcagc agcgcgagct gatcctcggc gaatccatcg ggctcgtctg
  1405921 tgccccagac agaatagaag gcatccatgg cgccgatgct gcccttgcgg gtgaagcgct
  1405981 cgatgtgaaa gatcacatcg gtacacccct cttccctcaa ctccggcagg cgataaaaat
  1406041 cgaccggcgc gcccttgccg atctcccgtc gcaactcgct ctcacccgtt tgccgcaaat
  1406101 ggttgaatgc cgaactttcc cacgtctcac gaacattccc gctgtcgctc gacgagtagg
  1406161 tctggagcgg tcgcgggccg ttatcctgtg cccgccactc gaaggcgtgc ccctcgaatt
  1406221 ccggatgcag tgtgtccatg aggcccatcg cgtaggaaat cgggatgccg gccctgctgc
  1406281 agcgttcgca gaaggcgcgg aacatctggt tcggctcgtc gccgcgcagc ccggcattgg
  1406341 ccagccagcg gagaatatcg atctcttcgt cctgcatcta tccaacttca aatcgaaggc
  1406401 caatcgttag cgtcgattcc atctgtcgcc tagagcaatt tcggattcca ggggttcggc
  1406461 agaccgttgt cgtaaaaaag ccatccagga attcaaaagg cgcttgacct tcccattgtt
  1406521 ggaaggatta tcaagggtgc agtttggaaa ggacgttccg atgactgcac tgaaacagac
  1406581 cgaaaaatcc acatcgcttc cgatgtcctt cgatttcgac atcgaaggta tgacgtgtgc
  1406641 ctcatgtgta cgacgcgtcg aaaaggccat cgccgcggtg ccgggcgtcg cttctgcgaa
  1406701 cgtcaacctg gccacggagc gcgcgacggt tcagttcaat ggagtgcccg aaacgacatc
  1406761 cgtgctccgc gcggtcgaga aagccggcta cgcgccgagg atcgtaaccg aggaaatcca
  1406821 gatcgaaggc atgacttgcg cttcgtgtgt ttcccgcgtc gagaaggcgc tgaaggccgt
  1406881 tcccggcgtt gccgatgcat ccgtgaacct tgccacggag aaggcgaccg tgcggctggt
  1406941 ttccggaagc gccgagattt cggccctcgc ggccgcggtc aaaggggcgg gctacggtat
  1407001 tcggaaggcg acgcctgccg aagccatgaa ggaagatgtg gatcaccgca cagccgagct
  1407061 ccgctctctg aaatccgcag tgacgatttc gtcgctgatg acccttccgc ttttcctgct
  1407121 cgaaatggga tcgcacttca ttcccggcgt ccatgacttc atcatgggca cgatcggtat
  1407181 gcgcaacaat ctctatcttc aatttgcgct cgccacgctc gtcctgttcg gaccggggct
  1407241 gcgcttcttc aggaagggcg tgccgaactt gctgcgctgg acacccgaca tgaactcgct
  1407301 ggtcgttctc gggacgaccg cagcctgggg ctattccgtc gtgacgactt tcgttcccgc
  1407361 gatactgccc tccgggacgg cgaacgtcta ttacgaggct gccgccgtga tcgtcacctt
  1407421 gattctcgtc ggccgctatc tcgagtcgcg ggcaaaaggc cgcaccagtc aggccatcaa
  1407481 gcgtctcgtc gggctgcagc cgaagacggc cttcgttttg catagcggcg aattcgtcga
  1407541 gactgagatc actgaggtcg taaccggtga cgtgatccgg atccggccgg gtgagaagat
  1407601 ccccgtggac ggcacagtca cggacggcag ctcctatgtg gatgagtcga tgattaccgg
  1407661 tgagcctgtt cccgttcaaa aagccacgga cagtgctgtg atcggcggta cgatcaacaa
  1407721 gaccggctcc atcaccttca aggccaccaa ggtcggcagc gacacactgc tggcgcagat
  1407781 catcagactg gtcgaagccg ctcagggctc gaagctgccg atccaggcgc tggtggacag
  1407841 agttaccgca tggttcgtcc cggtggtaat cctggcggca ttgctgacct ttgctgcctg
  1407901 gtacgtgctt ggcccctccc ctgcgctctc gttcgccctc gtgaatgccg tagcggtcct
  1407961 catcatcgcc tgcccatgtg ccatgggcct ggcgacgccg acctcgatca tggtcggcac
  1408021 cggccgcgcg gcggagctcg gcatcctttt ccgcaaaggg gaggctctac agagccttcg
  1408081 cgacgccgac gtcgtcgcgg tcgataagac agggacgttg acgaagggcc gtcccgagct
  1408141 gaccgatctc gtcgccgctg agggttttga gccggacgaa gtgctctgcc ttgtcgcaag
  1408201 cctcgaaacg ctttcggaac acccgatcgc ggaggcaatc gtgtcggcgg cgaagtccag
  1408261 ggggatagca acggttgccg tcagcgcctt tgaagcgacg ccgggatttg gcgtaagcgg
  1408321 gactgtttcc ggacggcggg tgctcgtcgg cgccgaccgc gcgctcgtca agaacggaat
  1408381 agatattacc ggcttcgcag atgaagcgga acgcctcggc agcggcggca aatcaccgct
  1408441 ctatgcggcc atcgacgggc ggctggcggc gatcgtcgcg gtttcggacc cggtcaagga
  1408501 aagcacacct caggcaatca aatccctgca tgcactcggc ttgaaagtgg cgatggtcac
  1408561 cggagacaac cgccgcactg ccgaggcgat tgccaaaaag ctcggcatcg atgaggtcgt
  1408621 cgccgaggtg ctgccggaag gcaaggtgga cgcggtgaga aagctccgtc agggcggccg
  1408681 ctcggtcgcc ttcatcggcg acggcatcaa tgatgcgccg gctctggccg aagcggatgt
  1408741 tggcatcgcc gtgggcaccg gaaccgatat cgccattgaa agcgccgatg tcgtgctgat
  1408801 gtcaggagac ttgaacggcg ttgcgaaggc gctcgcgctc agcaaggcaa cgatccgcaa
  1408861 catcaagcag aacctgttct gggccttcgt ctataacatc agtctggtgc ccgtcgcggc
  1408921 cggcgttctt taccccgtga acggcaccct gctctcgccg atctttgcgg cggcggccat
  1408981 ggcgatgtcg agcgtctttg ttcttggcaa tgcgctgcgg ctgaaatcgt tcgatccggc
  1409041 ctagggcaac tccaggaaag gtgcgtagcg gtttttcgtc cggagttgcg gaaaacaaga
  1409101 ggttagaaag tttccgtgat tggagaaaag cggagatgct ttaggcgcgt ccggtcacac
  1409161 gcgggacgcc cgttctgaag aaaggagaaa gacatgaata tcggcgaagc ctcgaaagta
  1409221 agcggcgtct cctcgaaaat gatccgctat tacgaacaga tcggcctgat cagccctgcc
  1409281 gtcaggaccg cctccagcta tcggacctat ggcgacaacg acgtccacac gcttcgtttc
  1409341 atccgtcggg cacgcgatct cggattttcg gtggagcaga tcaaggagct gcttgccctg
  1409401 tggcgcgatc gttccagggc gagttcggac gtgaaggctg tcgctctgga gcacattgca
  1409461 gaactcgaac gcaagattgc agcgatccag gacatgacgc gaaccctcaa gcatctcgcc
  1409521 agccattgtc acggcgacgg ccgtccggat tgtccgatca tcgaagaaat ggccaagggc
  1409581 ggcggagctg ctaaaaccga aatcaatccc cgcttcggcg tcgcgtcgtt gaagtaagcg
  1409641 cccgttcgaa gaggcgcagc agatatcctt gctcgaaatc ctgaatgctg ggcatcagca
  1409701 gcctctttgg cggctttcgg aatgcatcat gcagccgcag gtaaatccac ctgcccaccc
  1409761 ctgcaagcac agctggcaag cgggaacaag accggctgtc cggcaattgt gcagctgaga
  1409821 acgaggttct cctgccgacg gacgccccgg tcggcgtcca tcgatttcag gagtcaagcg
  1409881 atgaaaattg cgcagatcgc accccttgca gaacgcgtcc cgccgaagct ttacggaggg
  1409941 acggagcgaa tcgtccattg ccttaccgaa gagctcgtta agctgggcca tgacgtgacc
  1410001 ctctttgcca gcggcgattc gctcaccagt gccgaactgg tgccctgttg cgatgttgca
  1410061 ctcagactta atccgaaggt gcgcgatttc cttccgcatc atgtggccat gctggaagaa
  1410121 gtccgccgcc gcgcgcatca attcgatatt ctgcatttcc atatcgagtt cctgcatttc
  1410181 cccctcatca aggatttcgc cggcaagacg gtgacgacgc ttcacacgcg cctcgatctg
  1410241 tcggacgtgc atcccttcta tctggccttt ccggatgtcc cgctggtttc catttcggag
  1410301 caccaacgaa cgccgatgcc gccggtcaac tggagaggca cggtgctgca tgggttggac
  1410361 ccgaccgttc tgccgttcaa ggaaaggccg tccggagctt acctggcctt tctggggcgg
  1410421 atttcgccgg agaaaggccc cgatcgggcg atcgagatcg ccgtgcgggc aggcatgcct
  1410481 ctgaagatcg ccgcgaaagt cgacgctcag gacagagact attgggattc ggttgtcgag
  1410541 ccactgatcc ggaggcattc caatgtcgaa tatgtcgggg aaatcggcga aagccagaag
  1410601 gcggactttc tcggcaatgc ggctgcactc ctcttcccga taaactggcc ggaaccgttt
  1410661 ggcctcgtca tgatcgaatc catggcgtgc ggcacgccgg tgcttgcctt ccgttacggc
  1410721 tcggcgccgg aggtgatcga tgacggcgtt tcggggatcc tggtcgacac ggtggaacag
  1410781 gccgtcaagc gccttgaccg agtgctggga ctcaaccggc ggaaggtacg ggagagcttc
  1410841 gagaagcggt tcaccacgga ccggatgacg cgggattata tagacatcta tcgaagtctg
  1410901 ccgagcatcc gagcaccagc tgaccctacg ccggaggagg agccgaagaa agtggggctc
  1410961 gaggcggcgt gaggaacacg cccgacgcga acaatgcatt cgcgtcaggc gttatccgtc
  1411021 catgaaggct cgcctcctag ataccgtgcg ctatggcgat cggcgcgaca gagctccgtc
  1411081 gatcggcgct ctggcagacg cgttggtggc cggtgcggcc cgggctgagc cattgtcgct
  1411141 gggagaattg ttgcttctga taggcgaccg gagtttcggc gcggtcctcg ttctggcggc
  1411201 cggtgcaaat ctgtctccgg cggggttgat cccggcggcg tccactctgc tggctgttgt
  1411261 cgtcgtcttc gtctcgctgc agcttgtcgc gggcctgcgg catatctgga taccccactc
  1411321 tctgcgccgg aagaagctgt cccctcggct tgtcgagggg acaggacgga cgatgaagac
  1411381 gtggtcgcgc tggctcgatc cgtggctgac gcgcggactg cgcccgttgt cggaacctcc
  1411441 cttcgaccgg ctcgccggtt tgatctgcgt gcttctcgcc gtgccagttc cgctcctgga
  1411501 attcgtcccc ttcgtcacga atgttccgat gacgatcgtt gccgtattcg gcctggggct
  1411561 attggtcaga aacgggttcc tgctggcgct tggcttcgct gccagtcttg cagccgccta
  1411621 tttcgcctat aggcttctca cgctgtgatg gcgccgctgg gttactgtcg ccaaaccggc
  1411681 ttttcgctcc gatgggtaaa aagggcaata catcaaagtc gcaatgaacc gggaacgtcc
  1411741 ccgagcccgg aacgttttcg atccatatgg cagccggctg gcgttctaaa atctaaaaat
  1411801 tggagttcag caatggaacg gacgaacgca cgtaaacttg caaccgagta cctgcgcctc
  1411861 ggcggccatc gccgggtcgt gatcgacgat aaccagacat cggtcagaaa ctgggaaaac
  1411921 gagcctgccg aagcggacgc cttctggagg agaaatatcg aaacgctgcc gccggagatg
  1411981 cagcgcgaag tcgaactgct tcttccgacc atcaatcgtg cctgagtcga ttggagtgag
  1412041 atccggaaag ccgatggatg cacctgcgga agcgatgaac atgaatcccg gcccagagcc
  1412101 gttgaatttg gcgccatgcg ccgcctctga ttggtggacg cagcaccgtg gcgactcgcc
  1412161 cgtagttgcg accgccattc acgatggtca tgctgttcga gacgcggtgc agcgtctctg
  1412221 cgcgcttgat gaggcggaac gcctgcgcga ggaagacccc ttcacagagt ttttgatccg
  1412281 cgacttctca aaccggatcg tcgtccaccg ctcccgtttc gaagtcgaca tcaatcgtcc
  1412341 ccgcgcaggc gcggtctatc tgcggccgga gcaggcctgg ggtctcgacg tctgggcgga
  1412401 ggagccgccg caggccgttg tcgatgcatc gctttccatg cacgacgaat attacgagat
  1412461 gctgaaatcg tttctcgctg gcatcgaacg ttgccacggg cgcttcgtcg tcctcgacgt
  1412521 gcatagctac aaccatcgcc gtgccggacg aaaagcggag gctgcgcccg ccgcggatgc
  1412581 tccggatatc aatatcggca ccatctccat ggaccgtcga aaatgggcgt gcgtcgtcga
  1412641 tgatttcatg gcggcgttgc gctccttcga ttttccgggc ggatcgctgg acgtgcgtga
  1412701 gaacgtcgct tttcagggcc ggggcgaaca gacgcgggtg agtaggccgg agggatttca
  1412761 cctgccggcc tctcgtagaa cggtgcgtga acctctcgat tcacaccgct cccatcaggc
  1412821 aaacaggttc gttccgaacg cctgccagtg tacgaagagg ccccgattat ctcgagcaag
  1412881 ttgccgcaag aactgcgaag cccgagtttt gtggaaccga aagcgcttgt actttcgcat
  1412941 aatccaggcc ttgagcttcc gattgatgta gtcagccaga gagaacaggg ccgaacgact
  1413001 gaaccgccca taataggcaa tccatccccg caggagcgga ttgatctgtt tggcgatttc
  1413061 agccagcgtc cccggcgttt gccgcggaat gttcaagctc ttgatcgtgg cccgcatcga
  1413121 ctttagcgcc gtcgggctgg ccgccggggt gtagccgcag aagaactcat cctgctgcgc
  1413181 cgtcgccacc tgtcgcggcc ggaattggta tccaaggaag tcaaatttga cggtcggata
  1413241 ccttttccga cgccgattat ctttgcagta gacgatctgg gtcttgatcg gatgcatctg
  1413301 aagtccgcat tctgccagcc gggcttgaag cgcagccttg agggcctgtg cttcttgctc
  1413361 ggtccggcag tgcacgagac catcatcggc ataccgacac catggaagat cagggtgcgt
  1413421 ccgagtcatc cagacgtcga acgcgtaatg caggaagaga ttcgagagga ttgggctgac
  1413481 cacgccccct tgcggggtac cacgtgtgcg ctcaatgact gctccgttct tttccatggg
  1413541 cgcgaccagc catctttcga tgtagagcag agcccagttg catttgacgt gctttctgac
  1413601 cgccttcagc aagagatcat gcggaagatt gtcaaacagc cctttgatgt cgaattccag
  1413661 aacccaatcg tacttccagc accgctgacg cgtcacccca acggcatcca acgccgattt
  1413721 tcccggcctg tatccgtagg agtccggaag aaagagggaa tccaaatccg gctcaatcat
  1413781 ctgcttgacc accatctgcg cgatccgatc gctgaccgtg ggcacaccca aaaccctttc
  1413841 gccaccagtc ttcttcggaa tggagacggc gcgcaccggt ggcggaaagt aggtcccgga
  1413901 cgacatccga ttccagatct tgtagagatt tctcgcaagg tctttctcga acatctccaa
  1413961 ggtctcaccg tccactccgg ctgcgccatg gttggctttg accgctttgt aagcttcgta
  1414021 cacttgccgc ttctcaattc gaaacggctt gtctgtcgta tctatcgaag tcatcctgtt
  1414081 tccagttgtt ccaagcaata cgaccacctg atccgacccc tttgctccga ccccattaca
  1414141 gggtcctcaa cgctcatacg gatcggtccg ccccagtctc ctgcatcggt actctcgcct
  1414201 tgcggtttgc tccgcttggg cttctccctt ggcatcagga gcctggttcc tgcagttccg
  1414261 cgtgaaagcc tgtgtccgac tcacgccccc tctacgccgg tcgccacccg cccagtcatc
  1414321 aggcgcctgg cgggcttatc ccaggatgac gaaacggtcc tggtttcgac gacgcttgaa
  1414381 tttcttaacg acgcgtcttc ggagggttca ctttcgttcg tctttcggac acgcacctgc
  1414441 tcggatctcg tccgaacttt tcatccgacg ctcaccacca cgactcttta ccgcagcagc
  1414501 tcggactggt ttgagacccg ctcctgaaag ccgatcccgg agggccatcc tccatcattc
  1414561 acacagcttt acgacacagt gtcagttcat actgaactcc ttccgtgcct ctgcagcaca
  1414621 ctttcatcca tgaacacttc cccgaaacag gctgtgcgat cgccgtcgag ttcaagaaat
  1414681 tcttcatgga ggaatggaca ggcgagccgc ggccagaagc gctggtggcg ttgaggagaa
  1414741 tgctcgccgc gacgctgccc gttctcgttg aagcattgaa ggcggaacga tgaagctagc
  1414801 gcgcgcatcg atccaggccg aagcgaacca tcccgattgg ctggcggagg cgcttgcggc
  1414861 gatccatgca gggaaagccg tacgccagga attcgcaggc ggcgggcgcc ttcacatcga
  1414921 tagggccctg ccctttctct gcgtgcacct tgccggcgat gccgcacctg ttgcccgcga
  1414981 aatcgtccgt gcaaacgcct cccacctgct cgcgccggat gctgccacgg cgaagcccct
  1415041 cgtcacagcc attggagaat tgctcgagcg tcgcttcggc gccttcatgg ttctcgatat
  1415101 cggcgaactg gcaaaagacg agctcctgac cgacaagtct cctttcctgc cgcccttcaa
  1415161 ggtcgatgtt atggcggacc gccggcgaaa tatccaaccc gcagcaaagg cctttatcga
  1415221 cgccgtcgag gcgaccctgg cgcagttccg cacgccgcgt gtcgagcgtc acgaatggca
  1415281 ggcgtatcgg gaagaagaag cactcgatct gccattccct tcgatgcggg ttcgtttcgc
  1415341 gcctatctat cggcagcctg actccggtca ggttttcccg gaactacgcg agcggctgat
  1415401 cgccaccatt ttcgacgccg ccctgcacgc ctttgctgcc ttcgcgaagg cgacgggcag
  1415461 cctcgaattt ccctctcacc gcgcgctcgg cagaagagct ttcatcgatg ccgtggaacg
  1415521 aacggaccgc agcatcgatg aggtcgcctc gagtttcgat tttctcctcg ccgtcacgcc
  1415581 cataaacgcg gaagccgcct ggagcgagtt tgcggctggc ggcttcgcgc gttcgccgcg
  1415641 attcctctac cggccgttgg tcatcgaaat cgagaacgcg aagaagatgc ttttctcgat
  1415701 ccccttcgat catctcgaag acccggtgct ttaccaactc tatcgtgaaa agcagcagga
  1415761 gctggatctg cagctatcga tgctctccgc ccgcgagacg aagaaattcg tcgaatatag
  1415821 tcgcgccctg tacggcccgg tcgagccgaa tctgctgcga gcagccgaaa acatcctgga
  1415881 ccaaagccga aatctcgccg gttacccggc ggcacccgca gccgaactgc gcgccgacag
  1415941 ccatgtcatc gagaagaggg cgcgccagat gatcgacgcc tatgcacagc gctatgccgg
  1416001 attcgaagcg cttgtggaga tacgcgacga tctacccgcc ggcttgctgg tttcaggtaa
  1416061 acgactgttc atcgcgcgaa gcaccagcat ggcgcccgat cgcgtcgaac cgatcctcag
  1416121 ccacgagatt ggcgttcacc tcctgaccta ctttaacggc tcggcgcagg gccttagact
  1416181 gtttcgctcg ggtctcgccg gatatgaagg gatgcaggag ggccttgccg tcttttcgga
  1416241 gtatctttcc ggggggatga cgggcgagcg attgcgtctc cttgccgccc gtgtgaccgc
  1416301 ctgcgccgca atgcttgagg gcgcgtccct gccggaagtc tatcatcggc tggtagatga
  1416361 tcacggcttc cgagaagcag acgctttcaa cgttgtcgtg cgcatctatc gcggcggagg
  1416421 tctcgccaag gatgcgatct acctgcgagg gcttctgcaa ctgctcgatc acctggcagg
  1416481 tggaggcgca ctcgagccct tctggatggg caagatcgcc gcctctcatt tcgatgtcat
  1416541 gcaggaactg cacgcccgtg ggctgctccg cggcccgtcg gtcctcccgc tttttctcga
  1416601 tagtccagaa gcgtcgtcgc ggcttgccag aacgtgcgag cggatggctc cactcgattt
  1416661 gctgcagcaa taggagcggc caacatgcgc atggcctttt tcgtcaactc catcgaaggc
  1416721 gaagcatcgt attacacgac gacttggctg gcgcttgcgg cactcgcacg cggccatgag
  1416781 gtctgctacg tcacgccggg cgatttcgtg ttgcgccagg acgacagcct gctgatccgt
  1416841 gcaacgacgc tgaggggcac gaagccgaaa aaacccgaga cgttcctcgc cgcgctccaa
  1416901 ggcaaacagg ccgagatcgt tacgctcgat ctgcgcgagg tacaggtgct tttcctgcgc
  1416961 aatgatccgt ccgaagacgc agatacgcgt ccctgggcgg tctatgtcgg cacgaatttc
  1417021 gggcgtctcg ccgctgcacg tggcgtaatc gtcgtgaacg atcccgacgg cttgtcgctt
  1417081 gcgcagaaca agctctactt ccaggagttt ccagagatca tccggccgac cagcctgatt
  1417141 tccagaagca tcgaggagat ccgcagcttc cttgcggatc acccgggcgg ggccattctg
  1417201 aagccgttgc aagggtccgg cggcaaaaac gtgttcaaga tcgattccaa ggacgagacc
  1417261 aatctcaacc agatcttcga ggttgccagc gatggcggat acctgatcgc gcaaacctat
  1417321 attcccgacg cggtcgcagg cgatatccgc ctctttttgc tgaatggaaa accgctcgag
  1417381 cgcaatggcg tttacgcggc cttcaggcgc gtccctgcca aaggcgacgt tcgctcgaac
  1417441 atgcatgcga gcggcaccgc ggaagccgcg acaatcacgc cagagatcct cgagatcgcg
  1417501 gaacggctcc gtccaaagct gatcgaagac ggcatgttcc tggtgggtct cgacatcgtc
  1417561 ggggacaagg tgctcgaagc caatgtcttc acgccgggcg gcctccccga aattgcagcg
  1417621 attcatggtg tggacttcag cgaggacatc atcattgcac tggagaacaa attgcggatt
  1417681 caggagctct atcgcgggaa ggttcagaac cgaacgcttg cgatcctttg atgggcgccg
  1417741 gcttgggacg atctgtggat gtcccgacca gagcgtctcg ccgacaataa aagtgagttt
  1417801 acaaaagtaa tataatatga ttttttctct tcagctgcgc ggagagcagc attctttggg
  1417861 aggaaatcat gaaactcatg aaggcacttg cgagtgcaac gatccttgct gcctgcactt
  1417921 tcggcagcgc ttcggccgcg gatctcgtcg tcggcttttc tcagatcgga tcggagtccg
  1417981 gctggcgcgc agccgagacg acgctgacga aacagcaggc agaagagcgc ggcatcgacc
  1418041 tcaaatttgc cgatgcgcag cagaaacagg aaaaccagat caaggcaatc cgttccttta
  1418101 tcgcccaggg cgtgaacgcg attcttctgg ccccggtcgt ggcgaccggc tgggatgaag
  1418161 tgctggaaga ggcgaaggat gcggaaatcc cggtcatact gctcgaccga accgtcgacg
  1418221 cttcaaagga tctttatctg actgcagtca cgtccgatct cgttcacgaa ggcagcgtgg
  1418281 ccggcaaatg gcttgtcgac accgttgcgg gcaagccgtg caacgtcgtc gaactccagg
  1418341 gcaccaccgg ctcctcgccg gccatcgacc gcaagaaggg ctttgagcag gcgctctccg
  1418401 gcaacgacaa tctgaagatc gtgcgtagcc agacaggcga tttcacccgc acgaagggca
  1418461 aggaagtgat ggaaagcttc ctcaaggccg aggacggcgg caagaacatc tgtgcgctct
  1418521 acgcccataa cgacgatatg gcggtgggcg cgatccaggc gatcaaggaa gccggcctga
  1418581 agcccggcaa ggacatcctc gtcgtctcaa tcgacgctgt gcccgacatc ttccaggcta
  1418641 tggccgccgg agaagcaaat gcgacggtcg agctcacgcc aaacatggca ggccctgcct
  1418701 tcgatgcact tgcagcctac ctcaaggacg gcaaagagcc tccgaagtgg atccagacgg
  1418761 aatcgaagct ctacacccag gccgacgatc cgatgaaggt ctacgaagaa aagaagggtc
  1418821 tcggttactg acctcgctta cggcccgcgg cgggtgtcgc gggccgttca acgaacggac
  1418881 gcctgcgcgt tcgtcggacg cgatccagag acggtatcca tgcagaccaa cagcgacaac
  1418941 atcctttcag ccgtccggat cgaaaagggc ttccccggca caaaggcgct cgacaaggtc
  1419001 gatctgcatc tgcggcgcgg cgaggtccac gcgctgctgg gtgagaacgg cgccggcaaa
  1419061 tcgacgctca tcaaatgtct gacgggtgcc tatcgccggg atggcggcag catcctcctc
  1419121 gacggagccg aggtggaccc ccgcgacacc ttcgaagccc agaggcttgg catcgggacc
  1419181 gtctaccagg aggtcaacct gctgccgaat ctcacggttg cggagaacct ctatctgggg
  1419241 cgacagccgc gccgtttcgg catggtggac acgcgcagca tgaaccgcaa ggcgcgcgaa
  1419301 ctgctggcgg agtacgaact cgatatcgac gttacccgcg atcttgcgag ctattccgtg
  1419361 gcgatccagc aggtcgttgc catcgcccgg gcagtggatc tttccggcaa ggtactgatc
  1419421 ctggacgagc cgaccgcaag tctcgatgcg cacgaggtgg agatgctctt ccggatcgtg
  1419481 cggcgcctca agaagcgcgg actcggcatc atcttcatca cccacttcct cgaacaggtc
  1419541 tatgccattt cggaccgcat caccgttttg cggaacggac aattggttgg cacgcgagag
  1419601 gcgagagaac tcgacagacg cgaattgatc gccatgatga tcggccggga actggcgacg
  1419661 gaaatccagt ccgtccatcc cgatgcggtc gagggcgaac cacgctacac cttcaggaac
  1419721 tatggccgcc gaggcaaaat agatcccttc gatctcgatg tccgcgccgg cgaagtcgtt
  1419781 ggcatggcgg gcctgctcgg ctcggggcgc acggaaaccg cagaaatcct cttcggtgct
  1419841 catcgcgccg acagcggtac ggccaaggtc gatggccgga cagtcgacct ttcctcaccg
  1419901 cgcgccgcca tccggcagaa gttcggcttc tgcccggaag accgcaagac cgccggcatc
  1419961 gtcggcgacc tctccgtgcg cgagaacatc gtcctcgcct tgcaggcaag gcgcggctgg
  1420021 acccggccga tcccgcgtgt ggagcagaac cggctcgcgg acctctacat ccgggcactc
  1420081 gatatccgaa ccgccgatcg cgagaagccg ataaagctcc tttccggcgg caatcagcag
  1420141 aaggccattc tcgcccgttg gctcgcgacc gaaccggact tgcttatcct cgatgagccc
  1420201 acgcgcggca tcgacgtcgg cgcgcatgcg gaaatcatca ggcttatcga aagcctgcgg
  1420261 gaaaaaggca tgtcgctcat cgtcatctca tcggaaatag aagagctcgt agcctacagc
  1420321 acgcgggtcg tcgtgcttcg agatcacgcc cacgtcgccg aactcaatgg agctcaattg
  1420381 acggcacatc ggatcgtcga agcgatcgct gcgaccaatg ggaggaaagc ctcgtgatgc
  1420441 cgatcatgcg gacctatgcc ggccggctgc tgcctcagtg cattgcgcta gtgataattg
  1420501 taatagcgat ttcaatcgtc tttcccggtt ttctaaactt gcagatccaa aatggccgtc
  1420561 tgtatggcag cctcatcgat attctcaacc gcggtgcgcc ggtcgttctt ctggcgattg
  1420621 ggatgacggt cgtcatcgcc accaagggga tcgatctttc cgtcggtgcg gttatggcga
  1420681 tctgcggcgc ggttgccgcg tcgctgatca cgtcaggaca ttcgcttgcc gagaccctgc
  1420741 tcgccacgct cgcaatcggt atcctctgcg gcatatggaa cggggtcctc gtagcctttc
  1420801 tcgacatcca gccgatcatc gccacgctcg tgctgatggt ggccggacgc ggcatagccc
  1420861 agctcatcac cgagggaacc attctcacct tcaacgagcc cggcctgatc tttatcggca
  1420921 gcggttcctt tatcggtttg cccatgccga tcgtgatctg gctggtgttc ggtctgctcg
  1420981 tggccgttct ggttcggcgg accgcacttg gcatgctgat tgaagcgatc ggcatcaacc
  1421041 gtcaggcaag tacgctctcg ggcgtgctca cgccggtcct tctcgtggcg gcttatgtgc
  1421101 tgtccggcct ttgtgcggcg atcgccggca tcattgccgc cgccgacatc aggggcgccg
  1421161 atgcgaacaa tgccgggctc tggctggaac tcgacgccat actggcggtg gtcgtcggcg
  1421221 gaacatcgct gctcggcggc cggttcagca ttgcggcctc ggtgcttggt gccatcatca
  1421281 tccaggcgat caacacaggc attctcctgt ccggcttccc gcccgagttc aacctcatca
  1421341 tcaaggcggc gatcatcatc ttcatcctgg tgctccagtc accgcgcttc cgcacggcat
  1421401 tctcgtttct gagcatcccg ggggcagccg gcaagccgac cgagcgagaa gcgaaatgaa
  1421461 gcagaaatat ctaccactta cggcgacgat cctgatcttt gtcttaagtt atgcgctctg
  1421521 cgccgcgcag tacccgaaca tactgtcgac tcgcgtgatc gggaacctcc tgaccgataa
  1421581 cgcatttctg ggaatcgccg ccgtcggcat gaccttcgtc atcctttcgg gtggcatcga
  1421641 cctgtccatc ggagcggtga tcgcgtttgc cggcgtcttt ctggcggtcg tgctggagca
  1421701 tggcagcatg catccactcg tcgccttcgc gcttcttctg accatcacga cgcttttcgg
  1421761 agcgctgatg ggggcaatca tccactacct cgaaatgccg gccttcatcg tcacgctcgc
  1421821 cggcatgttc ctcgcgcgcg gcatggcctt cgtgctgtcg atcgattcca taccgatcaa
  1421881 gcaccccttc tacgggacgt taaaaagcct ctattacaag ctgcccggcg gcgggcgcat
  1421941 cactctgatc ggcggcttga tgctgctcgt cttcgcaatc ggcattctca ttgcacacag
  1422001 gacccgcttc ggcacgaata tctatgcgct cggcggcggt acggcgacgg cgaagctcat
  1422061 gggcgttccg gtcgcggcta ccacggtcag gatctatgcg ctatcggggc tcctcgcggg
  1422121 gttgtccggc atcgttttct ctctctacac ctcggctgga tattcgctgg ccgctgtcgg
  1422181 cgtcgagctg gatgccatca cggccgtcgt catcggtggg acgctgctta ccggtggatc
  1422241 cggctttgtc gccggaacgc tcgtcggcat cctcatccag ggtctcatcc agacctacat
  1422301 caccttcgac ggtacgctct cgagctggtg gaccaaaatc ctgatcgggc tcctgctctt
  1422361 tgccttcatc ctgctgcaga aggggatcat tcacctgtcg cgccccgaac gacagcgggc
  1422421 ctagccgcag gagcgggcga gatgccgggg gccttcggta ctcaacgcgg aaagcgcacg
  1422481 agccatagac tggttgtcga cgaactcggg caggcagtgg ttggtggtga gttttctgtc
  1422541 ggcgacacgc ttccgggcga caccgacctt gccgcacgct tcaacgtttc gcgtacagta
  1422601 ttgcgtgaag cgatgaagac gctggccgcc aaaggcctgg tcgttccacg tgcccgcatc
  1422661 ggtacacggg tgctgccaaa agcacactgg aatctcttcg acagcgacgt gctcacatgg
  1422721 catttcggtg cgggtgtcga tgagaagttt ctgcgtcatg tgagtgaagt tcgcctggcg
  1422781 ctcgaaccct atgcggctgc ccttgcggcg cgccgcgcca gcgatgccga tatcgccagg
  1422841 atgatgcggc tcgccgtcgc catgggcgat gccggccaca gccctcacac gctggcgcag
  1422901 gccgatctcg agttccacct ccgcctcctc gaggcctcgc tcaacccgtt catgcgaacg
  1422961 gtcggcagcc tgatcgaagc ggcgctgatc ggcgtatttc agctgacgag cccgacggcc
  1423021 gatgaaacgg agatcgaccg tgtcgcgatc gcgcatatcc gtatcgtcga ggaaatcagg
  1423081 cgccgcaacg aggatggcgc gcgccgagcg atggagcacg tgatccgtgt cggccaggag
  1423141 cggctgatct tgaatctcaa ggagcggcag ggctgacggt acgcggaatg gcccctcatc
  1423201 cggacttccg gcaaccttct ccccgcaggc ggggcgaagc ggacccgtgg cgcgctacct
  1423261 cctttggcca gcagcggaga ggacggagca aacgcggctt cccccttctt cccgtcacga
  1423321 cggggagaag gtcgcggcag cgggatgagg ggctgcgcga ggcgcgaatt tctcgctctc
  1423381 atgcgctctc ccgattccga gcctgttgcc cgtttccgcg tcgaagaggt gcaactgagc
  1423441 cggatctata gcaagaccaa tcagctctcc gcccaccgcc gcggagcgtc cggtctccac
  1423501 gaccatcagt tccggttgag tcgcggacgt gatgtaggtg gccgaaccgg tcgactcgac
  1423561 gacaccgaca ggaatgtcga gggcgccctg acccgcaccg acgatgcgga tatgctccgg
  1423621 ccgaattccg acggtcaccg acgctcccgc tggaacggtt tcgacaagcg cgagccttgc
  1423681 ctgtgtcgcg ccaaggtcga gcgcgagatg tctgccatct tgctccacca ccgccgggat
  1423741 gaagttcatc gccggcgaac cgatgaaccc ggcaacgaag cggttcgcag gtcggtcgta
  1423801 aaggtcgagc ggacggccct gctgttcgat gatgccatcg cgcatgacaa caacatggtc
  1423861 cgccatggtc atcgcctcga tttgatcgtg cgtcacatag acggaggtcg ccccgagtcg
  1423921 gtcatgcagc gcgcggatct ccttgcgcat atggacgcgc aatgccgcgt cgagattgga
  1423981 caagggctcg tcgaaaagaa acgccttcgg atggcggatg atcgcgcggc tcatagccac
  1424041 acgctggcgt tgtccgccgg aaagctcgcg cggataccgc ttcatgaggt gtgaaaggcc
  1424101 ggtggtcgtc gccacctcgg ccgccgccct tagtgcctcc gcctttttca cgccgcggat
  1424161 gcgcaagctg taggtcaggt tctcctccac ggtcatgtgc ggatagagcg cataggactg
  1424221 gaaaaccatt gcgacgtcgc gcttgcgcgg cggaacgtcg ttcatccgcg ccccggcgat
  1424281 cttcatctca ccggctgaaa tcttctcgag cccggccagc gaccgcagga gcgtggactt
  1424341 gccgcagccg gaaggtccga ccagagcgac gaaggttccc tcctcgatcg ccagatcgat
  1424401 gttcttgagt gcatgatagg agccgtagaa cttgttgacg ccgtttagct cgatctgaag
  1424461 ggtcatttga gggctcctga agtgaggccg gacacaatgc ggcgctgcaa gaggataaag
  1424521 gcggcaagga tgggcgtcac atagatcgtg gcataggcca tgatgttgtt ccattcattg
  1424581 gtgttcggcc ccatgaaggt attcaggcca acgcttgcgg gctgcaactc gacagcctgg
  1424641 atcatcgatt tcgaatagac gaattcgccg aaggcttgca tgaagataag gatcgcgctg
  1424701 acgagaatcc cgttgcgggc gagcggcagc acgatgttga agaaggcacc aatgcgtgaa
  1424761 ttgccgtcga cgagagccgc ttcttcgagt tccatcggca cgctcatgaa agtagcgcgg
  1424821 acaagaacca cgaaaaaggg catgcttttg gcagcaatcg ccaggatgac ggcaaggcgc
  1424881 ggcgtgtcaa ggaggcccac ctgcgagaag ccgacgaaaa tcggcgtcac catcagcgag
  1424941 gcgggcagca cctggagcat gaggattaga aacaggccga tatcgaccca gacattgcga
  1425001 tagcgcgcaa gcacataggc gcatccgacg ccgagcacgg cgatcagcgc cacggagccg
  1425061 aaggcgatga cgagcgaatt ccagagatac cggcccatgt tgcggctctc ccagacatgg
  1425121 gcgtagatgc tccattgcgg ctcgctgggc caaaacttcg gcggggtcgc gaacatcgcc
  1425181 gagccggtct tcagcgcggt gatgtacatc cagtaaagcg ggaagagata gatggccgcg
  1425241 agcaccaacg cgacagccag catcaagcgg ttgcggaaag cgtcactcat cctctgacct
  1425301 catggcgcgt tgagcggaca taaacgacgg aggcgaacat cacgaagacg atcatgatca
  1425361 ccgagatcgt cgcacccttg gcaaaatcat actggcggaa ggaaaggtcc caggcccagt
  1425421 attgcgtgac attggacgta ttgttcggcc ctccggacgt gattgcggcg aagagatcga
  1425481 attgctgcag cgtgaagatg agtccgagcg cgacgatggc gccgatcgtc gaacgcatca
  1425541 tcggcagggt aatcgtccag aagcgttgaa acgcgttggc accatccagt tcggccgcct
  1425601 cgtagaggtc cttcggaatg cctgaaaggc cgaccgaaag caggatcatg ttgaacgacg
  1425661 tgcccaacca gatattggcg atgatgaccg cccaaagaga atggctcgga tccgatcgcc
  1425721 agaagatgtt gccggagatc acacccgttt cgcgcagcag aaagttgagt acgccgaagt
  1425781 cgcccgacag aatccagttc cagatggcgc ccacgacgag gccgggcatg acccaggaga
  1425841 cgaggaagag gccgcgaagc caggacgcac cggggaaact gacccagaag aagagcgcaa
  1425901 gaccgaagcc aataagaaac tggcccgcga tcgaggccgt cacgaagatg gcggtattga
  1425961 ggagaatggg ccaggtttca ggctggccga aaaggtcgat ataattcttg aagcccacga
  1426021 acggccgcga aaagctgccg aggctgaaca tgtcgacctc ctggaagctc atcacgacgt
  1426081 tgtagacgag cggcagcccg gaaagaacga acaggaaggc gagcggcaag ctcacgaggc
  1426141 cgacatcaaa gcccctgcca tccgtgatgc tggataaaat tctcttcatt tgcgatcacc
  1426201 tgtccgttga gccgctgatg gtgcggacta cagcgctgcg caccatcagc gcgcaacatg
  1426261 cagtgtgcgg cggcgacccc ggccgaagcc ggagatcgcc tctctcggga gaaaatgcgg
  1426321 ggacggatcg tcgcgacaac ccgccgatga attccgctca ccgtttcggt ggcgcggtgg
  1426381 gtcagccaag aaccgccttg atcttctccg ccgcctggtc gagcgcttcc ttcgagctca
  1426441 tctgcccggt aagcgccgcc tggatggcgt cctggatcgc cttggagatc ttgggccatg
  1426501 cgggatgggg gccacgcggc ttggcatatt tcagctgctc cacgaagacc tggagagccg
  1426561 cgtccttttt cggctcgccc gtcgccggaa tggcgatgtc cgaacgaggc ggcagttgtc
  1426621 cgaagtcctt gaacatccgg tcgtcctggg aaacgaaata ttcgaggacc ttgaaggcct
  1426681 cttccggatg ctcggtgttc gcaaagatcg cccaattgaa atcgcccatg gccgaagagc
  1426741 gttcagcgcc ggcctgcggc acgggcatca gcgcgacgcc ccaatcgaac ttcgcttcct
  1426801 cgagcatgcg gtcgagttcc caggggccgg aaatcgccat ggccgcgttg ccggaattga
  1426861 aggtaccggt ggcgtcccat tggctgcgtg tcagcgtgtc cggcgaggca agcttctcgt
  1426921 cgatgatcgt cttccagacg tcgagcgcct tgaccgcgcc ttcggaattg atgttgtcgt
  1426981 aaccaccccc ggccatctgc gcccagggca gaaactggaa tgtcccctcc tcgttggcct
  1427041 ttgccgaaaa ggtgatgccg tagacgttct gagcggggtc gctcagcttg cgtgccgcct
  1427101 cgaccagttc gtcccaggtt tgcggaggct tgttcgggtc cagacctttc gccttgaaca
  1427161 tgtccttgtt gtaataaagg gcgatcgtgt tggtcgcctt ggggataccg taatatttcc
  1427221 cgtcccaggt cacggaggcg agcggcccct tgaaatagtt ctccggcttt acgacggagg
  1427281 acttcgcgat catgtcgctc agatcgagaa acgcgccgcg agacgcaaag agcgcgtgtt
  1427341 cgggattgtc gacggcgatg atgtccggcg cttgtccggt cgaataagcc cgcatggctt
  1427401 cgctgaccac gtcatcgaac tggatctgcc gatactcgac tttaataccg gagttcagct
  1427461 cgttgaaatc ctttatcaag ttcggtgccg gctgaatgtc tcgatcaagc gaccagactc
  1427521 tgatcgttac gtcctcggcg cttgcgccaa aggttgacaa ggaaacgctg gcgagcgcga
  1427581 atgcgcccag cattgcatat tttcggatac ccatggactc ctcctctttt gggttttccc
  1427641 gcgaccggcg cccccttacc ggccgtcggg catgcctcag gcccggtcgg ccacgaagtc
  1427701 gccgccgcgg ctgcctttca ggtaattcag agcatgcacc tgccccgtca tctccagtgc
  1427761 atcgcgatag accggatcgt gccatccttc gatgtcgatg gatccggacc agcccgcgag
  1427821 ccgaagctcg gagatgatgt cggtccagtt gctgtcgccg aagccgggtg tgcgcatgaa
  1427881 gacgaatttt tctttgccga agatgccgtg ctcgcgaatg acgtcccagc ggatcgtcgc
  1427941 gtccttgccg tgcacatgaa agatcttgtg cgcccattta cggatttgcg gcagcgggtc
  1428001 gatcagatag accatctggt ggcaaggctc ccactcgatg ccgatgttgt cgtcgggcgt
  1428061 ttcgttgaag atcagctccc aggcatccgg attgtgggcg atattccagt cgcccgttgc
  1428121 ccagttgcca tccatggcgc aattctcgaa agcgatcttc acgcccttgt ccgcggcgcg
  1428181 ctgagcgagc tcgctccaga ccttgcggta gcgcggcagg ctgtcggtca atggccggtt
  1428241 acggatgcgt ccggtgaagc cggcgacgca tgtcgcgccg aaatgatggg cgttgtcgat
  1428301 gcaatccttc cagccttgca gcgtctgcag atcgatgtcg gtttcctcca gcggattgcc
  1428361 gaacatcccg agcgtcgaga tcgtgatgtc gcggtcgccg atcgcgtcgc ggcagcgctt
  1428421 gccgagttcg gcaagatcct gtccgttggt ggtctgccaa aagaacggct cgaagctttc
  1428481 aaagcccaga tcggcgatct cgccgatgcg cttcgcggcc tcgcccttgg tggcgctgac
  1428541 catggtcccg atacggatgg atttggctgg attgctcatt atatgcctca ctcaaattgt
  1428601 aacgcgctgc cgggtccggg cgctttcgat cgccgcgaac accattgcaa ggctgttgat
  1428661 attgtcgtcg ccaaccgtct ccggcttggt gccggtacgt accgccgcaa caaaatcggc
  1428721 gatcacgctc gcatgcccct gcgtctcacg ggggtcagcc gggtcgggaa tttcgatggg
  1428781 ggcaagagga cggaagaacc cttcgctgcc ggcgacacgg ttcgcactga gcgcctcggc
  1428841 gccatcccag agcagcgtgc cttcggttcc gaggatgcgc cattcgctct cccagctcgt
  1428901 attggcgcct tcggcacacc aggatccgcg ataggtgaag gtcacatcgt cggcaagttc
  1428961 gaaaatcgca gttgcagccg cgccatgcgt gtaccaggag ccccgcggat tttcttcgtg
  1429021 gcaatagacg gcgagcggcg tcttgtcggc gatgaaccga gcggcatcga aggtgtggat
  1429081 cgccatatcg agaagcagca cgtgctccat ttcttcgcga aaaccgccga aatgtgcgcc
  1429141 gatgaagaag tcgcaatgga tggccgtcag gtcgccgatc gccccgcttt cgataaagcg
  1429201 gcggatgcgg cgtatgccgg cgatgaaacg gcggttctgt acgatcgcat gtatcctgcc
  1429261 cgcattgccg gcgagctcga tcaattcacg agccgcttcc agtgacgccg ccatcggctt
  1429321 ttcgctcagc acatggcagc catgacggag tgcggtcgcg acgacgtcgc ggcgcgcggc
  1429381 cggaatgact atgtcgaaga ggatgtcggg tgccgtttcc gtcagcacgg catcgagatc
  1429441 cgaaccgata acggcatctt cgatttcaaa ttccgccgcg agcgcacggg cggcctccgg
  1429501 attcacgtcg acgagcccga cgacccggat tatcgactga agttcgcggt ccgcggcaat
  1429561 cgccttgagc caacctctgg ccatagctcc gcacccgcaa agaactgcgc gaaaaatcac
  1429621 tattctcctc ccgcaaaccg gcgtttccgg cttgtcttgg tctccgtaaa cgtttacgga
  1429681 actatgcgga ctttccgaaa catgtcaata gggatttcag aagttcggtc ggaatgagga
  1429741 aaggcgggct gatggtgctc gctcgcccac cgggtctcac aatatcttcg atcccgtcaa
  1429801 tcgctagtat attcgagtga gccggccggt ggagaagtag gaaaacgctc cgcatgaagg
  1429861 gaattcggcg cctggcgcaa catctcgata tttcgatcgg aacggtttcg cgtgcattga
  1429921 acggccgccc cgacgttaac gaggagacgc gcaggcgggt cctcgaagcg gccgagaagc
  1429981 tcggctatgt gccgaaccag tcgggccgca gcctgaggca gggcaccacc aacatcattg
  1430041 gcttcatgat gcagaccggc acggagatca ccggccaagg cgacaccttc ttcatgagtg
  1430101 tcttcgacgg cgtgcaggcg gtcttcgcca ggcataagct cgacctcgtc gccctgctct
  1430161 gctcgtccga ggaggatcag agcgattacc tgcgccgcgt cgttgcgcgc ggtttcgccg
  1430221 acggcctgat cctctcggcc acgcagcggc acgatccgcg tatcgagtat ctggccgaac
  1430281 gcaacatccc cttcattacc ctcggccgaa gcctcacgga tgtcgggcgg ccctggctgg
  1430341 atctcgattt cgagggaatg gctcagatcg cgatcgaccg tctcgtcgcc cgtggacatc
  1430401 gccgtatcgc ggtcacccgc ccccatgacg acgccaatct cggctacatc ttcgtcgacc
  1430461 gctgccgcga agcgctcgcc gcgcatggcc tcactctgga ggaggagctg atcttccgat
  1430521 cgacgccgaa cgaaaccggt ggctatcaga tcgcacgcga actcctgaag ctcgaggacc
  1430581 ggccgacggc tgccttgctc gtcaacgaga cgatcgccat cggattttac cagggccttt
  1430641 ccgaagccgg cgtcaggccc ggccgcgaca tcgcggtgat cgggcgctac agcccgcatg
  1430701 cgcattttct ttcgccgccg ctcacctgtt tccgtctgtc gctgcgcgac ctcggcatag
  1430761 cgcttgcgga gacgctgctt tccactatgc cgactttcca ggagcattac ccgcaggcgt
  1430821 tgacaaatgc ggtctggccg atggagctca tcgaaggcga aagcgacggc tttcgcgtca
  1430881 atggcgacga aagtcgcggc tgacataggc ggcggcgcaa gggatcattt cggcaatccg
  1430941 caggtttgaa gcttgctgca tggttcctca aaccgggaac tgattgcagg atgagtcatg
  1431001 gagcacgcaa accgctacgc ggattcggcg cttggacgcc cgagcgccgt agcgaacccg
  1431061 ccggctgcag tccggattgg tgactgctcc tgaaaggaga tcccatgcgt ggatttatct
  1431121 tccttttggc cgggttgtcc gcaacgacgg ccctagccca cgacgctccg aatggttggc
  1431181 agtatccgag cgcctgctgt tcgacgatgg attgccgcaa ggtcgcacaa aacgacatca
  1431241 gcgagcgacc gcagggctac atcgtcagag ccaccggcga agtcctgccc tacgccgaca
  1431301 gcagggtccg tatgtcgccc gatggcgaat accactggtg ctccgcgtcg ggcaaagcct
  1431361 atgggaagac aatctgcctg ttcgtacccc caagagcata ctgactgttg cggtaaaccg
  1431421 gcgccgtcaa agcacccgcg ctccctcgac caggagcgcg gcgcgatggc gggcaaggcg
  1431481 tcagcgggga tcggctgagc cgagcttgtc gtccagggtc gacaagatcc ggtatgcggc
  1431541 cttgacgcga gcagcgatcg ggtaatttct gttcgcgagc atcacgatgc cgattcgctc
  1431601 ggccgggacg aaggctgtat aggcgccgaa cccgttggtc gatccggttt tgttgatcca
  1431661 aatatctttg cgcggcgcag acggcggaac gatcttgtca accttgctcg gctcgagagc
  1431721 catccgggcg gaattgccgg tcagcaagtc gtcgagtttt ggcggataag cgtacatctc
  1431781 ccatccgagg ccctgcgtca tggggcctac cttgaaataa ccggtatgcg ttgcggtgat
  1431841 cgcgtgccgt agcatttctt ccaggccggt atcgtcgatg cttgcctcta cgaagcgaag
  1431901 caagtcggca gcggtcgtct tcacgccata ggcttgcgag tcgaagacac cgcgcgtaac
  1431961 ccggatcggt ttgccggcct tcgaatagcc ataagcataa tcgtccatcc gatcgtctgg
  1432021 aacgctgatg aaggtgctct tcagtgccag tccccgaatg accgtctcct ccatcagatc
  1432081 ggcgaagggc gcgcccatgc ttttggcggc gagatagccg aacagaccta tgctcggatt
  1432141 ggaatagagc ctgtacgttc ctgcggcgta ggtcgggcgc cagcttttga agtattcgat
  1432201 catgctctcc tcaccggaga ccgcgtccgg aaactgcaaa ggcagtccgc cggccgcata
  1432261 ggtgcccaga tcgagaagtc tgatttcatc gaatggcgtt ccggatagcg ccgggagata
  1432321 tttgctggcc ggctctgcta aactcaaatt gccgcgcgct tcagcgtagg cggcgagcgt
  1432381 cgcagtgaag gtcttgctga tcgatccgat ttcgaacatc gtatcgtccg tgaccttctt
  1432441 cccgccctcc ttcgacgcca ggccatagtt gaagacgtat ctcttgccgc tcacggtcac
  1432501 cgcgacagcc atgccgggca cgccgttttc ctccatgagg ggccggatag cctcgtccac
  1432561 tacgcgtgcc agctgccctt catcaccttg ccctgctgcg tgagcgccgc ctccgcagga
  1432621 gagcagagcg atcgcagcca ttccagttgc tccgatggaa attttagtca tcacggatac
  1432681 atagacctcg cgtttgttgt tgcctgctct taggcgatca agccgaagag gcattcggac
  1432741 gagagatgca tatgagctcc gtacgcctcc gacaaacgac gatattttgc acgagccatt
  1432801 agaaaaattc aggctcactc cgctagaaat agagggtcat gacgatatcc tgatcgaaat
  1432861 cctcgaaacc cttgccgaag atattgagcc cgcccgggtt ctcggctttc tcgtcaatgc
  1432921 cgatgcgaaa gcggatcgaa tgatgatccg gaatgccgac agaatttatc ggatgcgtcg
  1432981 agaccattgc cccgccgcgg aacgaaccgg aagccagccg attagatgtg aaaggcaccc
  1433041 agattgtgtg tcggggccgc cactgtcatg atggtcagag gcatcctctc aagggtgggg
  1433101 attcacgacc ggacggagca tctcgcgcat ggcttggtcc ttcagaatcg gaacgatcgc
  1433161 cggcactgct attcgcgtgc acgtgacctt cgcgctgctt ctgatctgga tatggctgac
  1433221 gcactaccgg atcggcggca cggtggcggc gatggagggg attgctttta tcgtcgctgt
  1433281 ctttgtttgc gtcgtgctcc acgagttcgg ccacatagct gccgcccgcc gcttcggcat
  1433341 taagacgccg gacataacgc tgctgccgat cggcggcgtc gcccggctcg agcgaatgcc
  1433401 ggaggagccc ggccaggaat tcatgatcgc tatcgcaggc cctctggtca atgtggcgat
  1433461 tgccggggtg ctcgtcgcga tcctcggcag ctatacggca atggggcaat tagctgacgt
  1433521 cgaggacccg cagagcggtt ttctcgccag gcttgccggc gtcaatgtct tcctcgtgct
  1433581 cttcaatatg atccccgcct tcccgatgga cggcggtcgc gtgttgcgcg cggcgctcgc
  1433641 atcccggctt agctggtcgc gtgcgaccca gatcgcggca accatcggac aggggcttgc
  1433701 cttcgtcttc ggcttcgccg gcctgttcta caatccgctg ctgatcttca tcgcgatttt
  1433761 cgtctatctg gccgcaacgg ccgaagccca aaacgcccag atccgcgagg tctccagcag
  1433821 cgtcatgatt gccgatgtga tgattaccga attcacgacc ctcgatcgct cggcaacgat
  1433881 agatgaagcc atcgacacat tgctcgccac gacacagcgg gagtttccag tggtcgatct
  1433941 tgccggccat ttcgaggggc tgctgacacg cgacgacatg atccggacac tcaaggaaaa
  1434001 aggtgctgcg acaccggtgg tcgctgcgat gcgccgggac gtgcccacca ttcatcatcg
  1434061 caaacgcttg gaggagagcc tgcggctcat gcaagaatcc cattcgcctg cggtcgcggt
  1434121 cgtcgacggc tcgaatcgcc tcgtcggatt gatgacacac gagacgatcg gcgagatgat
  1434181 gatggtgcgt gcagccgccg ccggccgctt tcgattcgga cacctgcggc agaccggaag
  1434241 ccgagggtaa agtccaggtc ggatggaacc gaatccatgc tttggagttc ggacgatatc
  1434301 ttgcaggcgc tgaagcgctt cgaatcgctg catgtcttcc gatgagccgg cccttgatcc
  1434361 ggccgtgctt ggaggcgcat gcatcatgca gtccgggttg aatcatgctc gtgacggttg
  1434421 aagtcatcac gatcgttctg gtcgcgatcg caacagcact ggcccttgcc cacgcactgg
  1434481 agtggcccgg caaactgcgc ctgccgaagg aacagtatct ggcgattcag gcgatctact
  1434541 atccgggttt cacaattggc ggcgtggccg agccgctgtc gctactcttt accgccgcac
  1434601 tcctcgtcct catgccgaga ggcacgccgg ccttttggat gacggtcggc gcattgatcg
  1434661 gcctgcttgc aatgcatgcc acctattgga tcctgacgca tccggtaaac aacttctggc
  1434721 tcaaggacac gcaactggca aaaaccagcg gacggttttt cgcagtgggc accgttcgcg
  1434781 ccaagtctgt tcctgaaagc gaagactgga ccgccctccg ggatcgctgg gagcgatcgc
  1434841 atgtcgtgcg ggccgctttc ggtttcgtca gcctggtcat gctcgcaacg gcaatagctc
  1434901 tctgacagga tttcccgcgc agtgcattct gctgacggga gcgtcgaaaa cgaacatcgg
  1434961 ggaaacacga tgtctacgca ctatctcaaa tacgcgctca atctcctgat cagcctggtg
  1435021 atcatgtatc tcgtgatgtt cacgatgatc gacggaatca acgacttcta caacaacccc
  1435081 aacatgttct acatggccat catgatggtc gcgccgatgg ccatgctgat gctcctgatg
  1435141 atggccccga tgtatccgag aaagaggttg aacctcgccc tccacctcgc cttcgccatt
  1435201 ctcttcatcg cagctttcac cttcatgcgc atgcagacct tcgtcggtga cgcgcagttt
  1435261 ttgcgttcca tgatcccgca ccattctggc gccatcctga tgtgccggga gtcctcgctg
  1435321 gccgaccccg agatcgccgc cttgtgtgaa cgcatcatcg actcgcagaa gcgtgagata
  1435381 gccgagatga acagaatcct ggcctgctac taacgcgctg ctaaatagaa cgggatcagc
  1435441 aaaaccgcat tttctcatcc cgctctagcc gctgcccagc cgcggtgcca gcagggcgac
  1435501 tgagatcgaa ccgaagccga ggaccttcag cgccgcaaca gccatgtgac cggtctccca
  1435561 tctgaggcgt accgcttcga aatccgccgg tatcggaccc ggctgccacg tggccagtat
  1435621 ggcgtttgcc ggcgcgacga gcgtgaacca cgctgccagg ccgcctgcga agaagccccc
  1435681 accggcgagc gcgaaccaga aagcaggccg ctcgttggaa agcagatagg aaaggaagca
  1435741 cgtagccaat atcgtcgcaa catcgagcgg cccgccgacc ttcgcaaaaa gtgcgaactg
  1435801 gccgttgaag acggttgcct cgcgccatag ttccggcgac cagacgaaca accgcggcgg
  1435861 tgcctccaga acatgggcga aggagggacc aaggctgagt gcgccgagca gcaatgatag
  1435921 aagacctgca agataaacga ccatggtccg tccttgcgcg tgtaacgcca gccagaattc
  1435981 caactttgcc gacaggtaag tgttccagga aaaacggaaa ccagccgctc tcgctgatct
  1436041 cacggaatgt tgttgatcca ggcctcactg cagccgccct tgtgccggta tgatccgcaa
  1436101 agaacggaga tcgtcaatgc acgcgaagat gccccgggtc ctgctggccg gcttgctgtt
  1436161 tctccttgta cccagccaag gtttcggcct cgacctgccg cgctcgaatc atcctgtatt
  1436221 cgaccgggtc gtcacgcttg tcgtcgacaa tttccatgat cccgctgctc tcgacggttt
  1436281 tggcgcagcg gttcggcggg aactcgatga cggccaacca ttgaactcag aaagcccggg
  1436341 gccccgggtc gataccgcta tcgagaggat cctcgcaagt ctcgaggcct cgcacacggc
  1436401 ccgcttcaag caggatacga tcgcatatta cgaacttgcc gacatattcc ggtttgctat
  1436461 tcgccacgac atggagcggc tgttcccgcc ggatggcgcg gcgacctatg ccggggtagg
  1436521 catggtcacc cggatggaaa acgggctgcg gttcgtaagc gacgtctatg acggctcgcc
  1436581 tgcggacaag gccggcatac gcgttggcga cgaagttctt tcggtggatg gcgcgccgta
  1436641 tcgcgagatc gattcctttc gagacaggat cggacgaacg gtggagatcc gccttcggcg
  1436701 cgaggcggac gcgcaacctt ttaaggccac ggtcgctgtg gagcgcttgc ggcccttgcc
  1436761 caccttcgaa aaggctatcg acaaaagcgt caccctccac gaagaggggg gacggagcat
  1436821 cggttatctc cgtctatgga cgctttccag tcccgatggg ctcgatatcg tggcgcgcga
  1436881 acttgccaca ggtcgcctca aggatgccga tggcgtcatc gtcgatctgc gcggccggtg
  1436941 gggcggcggc ccacccgacg cggcggagct cttcgtcggc gacacgccca acttccggct
  1437001 gattgcgcgc ggcagcaagg acatgctggc aaatgtacgc tggcgccgtc cggtcgtcgc
  1437061 catcatagac gagggctcta gaagcggcct cgaacttttc gcctatgcgc tgaagtccaa
  1437121 tggaatcccg cttgtgggga cgcgcacggc aggcgctctt cttgccggcc gcgcctatct
  1437181 cctgccggac gacagcattc tggagcttgc agtatcggac gcggtgatcg atgacgatgt
  1437241 gcgactggaa gggcgcggcg tcgaaccgga cattattgct accttccccc tgccttacgc
  1437301 cgccggccgc gacccgcagc gcgaagctgc ctttgaagaa atgcggcgaa cccttgccaa
  1437361 agactgaagc ggcgatcggt ttcctggacc gtcgcacccc tcgactattc gctttgccgg
  1437421 aagtttcgga ttcggtcgaa gagcactgca agaacgatgg cgccgccgat gaaggcgcct
  1437481 tgccagaatg cgttaatgcc aagcaggccg aggctattgc ggatcacctc gatcagcgcg
  1437541 gctcctatca gggcgccgga cgccgtaccg acgccacccg ccagattggc cccgccgatc
  1437601 acggcagcag cgatgacctg aagttccatt cctgcgccga tattggtggt caccgccccg
  1437661 agccagccgg tctggacgat gccggcgatg ccggcggcca acgcagagat catgtatacg
  1437721 atgaccttga tccgcctgac cggaacgccg gtgagccttg ctgcatgctc gttgccaccg
  1437781 attgcgaaaa catagcggcc gaacttcgtc cagcgcagca cgaagccggt cacgagcgcc
  1437841 aggacaatca tatagagaac cggattggcg atgccgaaga accatgcgcc gccgcccagc
  1437901 gcgagcagcg catcgtggtc cggtccgaac tcgaagacaa ccgtattgtt ggatgcgacc
  1437961 atcgccaggc tgcgtgcgat cgagagcatg ccgagcgtga tcacgaacgg cggaaagccg
  1438021 agataggcta tcatgacgcc attgaaggct ccggccaaca aagccgtgcc gatcgaggcg
  1438081 gcaattccca cctcgatgcc gtagccggca tgcatgacga cggcaagcac catactgctc
  1438141 aggcaaagga ccgatcccac cgacagatcg atgccgccgg tgatgatgac cagcgtcatc
  1438201 ccaagcgcga tgattgcgac aaaggtgaaa ttccgcgtga tgttatagag gtttttggct
  1438261 gtggcgaagg agtcggtagc gacagacagg aagagacagg cgagaatgac ggcgataaga
  1438321 acccagaacg cctgacttgc gaacaggaac gagagccatc cccggtccct ctgaccgact
  1438381 gcccgatcga gcgtaattgc catggccaac cttcactttc gttgagaatg gttcatacct
  1438441 gttcgatggc accggtgatc aaaccggtca cttcctccgg agagctctgc tcgatcgcct
  1438501 tatcggcgac cttcctgccc cgtcgcatga cgattacgcg gtcggcgacg gtaaagacgt
  1438561 ccggcatgcg gtggctgatc agcacgacgg cgatgccgcg atcgcgcagc gcccggatca
  1438621 ggttgaggac ttccgcaacc tgccgcaccg aaatcgccgc cgtcggctcg tccatcagca
  1438681 cgatcttggc atcagacagc atcgtacgcg cgattgccac cgcctgcctt tgaccgcccg
  1438741 acatctgccg gacgaagtcg cgcggcggcg tctccgactt cagttccttg aaaatctctc
  1438801 cggcgcggcg gtacatcgct ttgtaatcga gaatgctcaa gggcccgatc ccgcgcctga
  1438861 tctcccgtcc caggaagaca ttagccgcag cggttaaatt gtcgcagagc gccaggtcct
  1438921 gataaacgat ctctatgccg tgctgccgtg cctccacggg gcggtgaagt acgatttcgg
  1438981 caccgtcgag ccgcattgtg ccctggctcg gcctgaagtt gccagcaatc atcttgacca
  1439041 gcgtggactt gccggcgccg ttgtcgccca tgagcccgac cacttcgcca cggttaagcg
  1439101 aaagcgatac atcggttacc gcctgaatcg cgccgaaatg cttggaaatg ttgacgagtt
  1439161 cgagaactgc cacagccgat tagcctcccg aagcagcggg ccgccttctc gatcgctcac
  1439221 ccgctcccgc actcttcccg gcaaggcgac catcaccatt tacgcaaatg cgcaggaatg
  1439281 cgtcaatcaa tagtcctaca aatgaccccg catatacgcg aaacatatat tgtaatacaa
  1439341 atattcgttg acgcgccgtt cacgcggata ttagctagtc ttcgggagga gagcatgctg
  1439401 atacttgctc ttggggcaca gggcaggatc aggcggcact cacagcgact ctgcttgacg
  1439461 aactgcgcgc gaattgccgc tcttcaatgc ctcgatcgat tgccgtcggc tgtgcatagt
  1439521 cgcagctaag cctgaaattt tcgtgattta aggcgcgggc acacgagtgc ccgcttgttt
  1439581 caagggagga aggaatgagg aaggcactat tgcttgccgt tgccgctctg gcactcagcg
  1439641 ccggaacgac catggcccag aagaaacagc tcgtcattgt ggtgaagggg ctcgacaatc
  1439701 ccttctttga agccatcaac cagggttgcc agaaatggaa caaggaaaat ccggactccg
  1439761 aatacgaatg tttctacaca ggcccggctt caacttccga tgaggcaggc gaggcccaga
  1439821 tcgtccagga catgctgggc aaagctgaaa ccgccgccat cgccatctcg ccgtccaatg
  1439881 cgaaactcat cgcccagacg ctgaaaacct caaaccctac cgtcccggtg atgaccgtgg
  1439941 atgcggatct cgcggccgag gattcggccc tgcgcaaaac atatctggga accgacaact
  1440001 acctgatggg ctaccgcatc ggcgagtaca tcaagaaagc caagcccgat ggcggcaaga
  1440061 tctgcaccat cgagggtaac ccgggggccg acaacattct gcggcgcgcc cagggcatgc
  1440121 gcgacgcgct gaccggccag aaggacctgg cggagctcaa gggcgaaggc ggctggaccg
  1440181 aagtggccgg ttgccccgtc ttcaccaatg acgacggcgc caagggcgtg caggcgatga
  1440241 cggacatcct tgccgccaac cccgacctgg acgctttcgg gatcatgggg ggatggccgc
  1440301 tgttcggcgc gccgcagccc tatcgcgacc tgttcaggcc ggtggccgac aagatcgcca
  1440361 agaacgaatt cgtcatcggt gccgccgaca cgatcggcga ggaggtcgcg atcgcgcggg
  1440421 aaggattggt caccgctctg gttggacagc ggccgttcga aatgggctat aaggcacctc
  1440481 aggtgatgct cgacctgatc gccggtaaac ctgtcgaaga cccggtcttt accggcctcg
  1440541 acgagtgcac aaaagagacc gcggacacct gcattcagaa atagccggcc aaagccgaca
  1440601 ccctgcggcg cgcggcgccg cagggtgtcg ggccaaactc agtggttcag atctgccagt
  1440661 ctgcatcgag cgcataggct ctaatgtaat cgatcttcat ttctgacccg tcgacgagcc
  1440721 catcattcgg cgtgccggcc atgccgccga cggcaaggtt gacgagcatg tacatcgggt
  1440781 cgtgcatatc ggcaggggta tcggcgcgtg caatcgccgc atcgtcgaaa taccagacga
  1440841 tttcttcctc cgtccaaagc acaccatagg tatggaagcc gcttgcgtcg gccaccttca
  1440901 ccgcattttc gatgctggcc ctcgagcccg tttcgttgga atgcaccgtg gtaatcacgg
  1440961 tgttggagtc ctgtccgcgc atttccacca catcgagttc cggcggccag gatccgtcgg
  1441021 cgggcagcag ccagaaggca ggccaaacgc catggtcgtc cggcatgtcc gcacgcattt
  1441081 cgaaataacc gtaggtctga gcgaaggacg agtgggtcgt cagcatgccg gacgtgtaat
  1441141 catagccgtt gatctcggcc tggatcgcct ccgatgccgg ggccgccgtg atcgtcagca
  1441201 cgccgttact gacggaaaac gggttggcgg aagcagtcgg cgcgtagctc ggattgatat
  1441261 accattgctg ctcgccattg ctggaaagtg tcgcgccctt ttccggcgcc caccagtatt
  1441321 tcgcgtccca gacaccgctt gtgccgtttc gcagatcgag cgtattgaac tcgtcggaaa
  1441381 aggtctgcga caggacggaa cggtcgagac tgagcctgaa ttggcgcgcc tccagttcgt
  1441441 ctgccgtcgt gttcgcgaag accaggctct cgccatcagc gagatgaagc cggagatccg
  1441501 cgccttcctg cgcgacattg gccagaacct gctcgaacga tgtgaagccg taatcgtcga
  1441561 ggcggataat gtcatcatag ttgaaatcgg tgatcaggtc gcttccgttg ccccgcgcga
  1441621 acacgaaggt gtcggcgccg ccagccccga tcaagacgtc gttgccgccg cggccgtcga
  1441681 tcgtttggct gcccgaaccg cctttaatga tgttatccgt ctcattgccg aaagcggaac
  1441741 ggccgtttcc agtgacggta aggttctcga aattctccgg aagcgtatag ctcatccacg
  1441801 tgtttatcgt gtcaacgccc tcgccggctg cctcgaaggc ccggttgatc gaggaataga
  1441861 gataatagat atcgtcgcct cgaccgccga tcatcgttac gttcacggaa ctgtcgcccc
  1441921 agatggaatc attgccggcg gtgccataaa gtgttggtcc tgacccggtg gcggaaaacc
  1441981 acgccgtcga actgccgctg tagtaaagcg gcgttccaac cgcgttcagt atggttctgc
  1442041 tcatcgaact ttctccagtt gattgatggt tttcctccgc tcacgatgcc tcctctcgtt
  1442101 tattctagag cgccctgtcg cgcatataac cccaaagagt tggggggcgg tgcggaacaa
  1442161 agccgcgatg gaggcgtttc ttggagttga cggcggccgc ggagggaaca tgcacggcgc
  1442221 agaaattcta cctaaaggtg tgtttgacga cgaaacaagt ttacacgagc ctgactttcg
  1442281 agccgtgctc gacgcgttga ctgtggccgt gtatgccacc gacgcggagg gggtcgtcac
  1442341 ctattgcaat gctgcagctg cagccatcgc cggacgcgag ccggaactgg gaaaggatcg
  1442401 gtggtgcgtc agctggcagc tgcgacggcc ggacggatca ccgcttccgc acgaacagtg
  1442461 cccaatggca cgtgcactga aggaaaggcg gccgatcagg ggcgaagaac tgatcgcggt
  1442521 tcggccgaac ggcgccgcgg ttccgcttct gccccaccca acgccgatgt tcgatgccgc
  1442581 tggcgcattg accggagcgg tcaatgtcct catcgatctc agcaacacca aggacatgga
  1442641 gcgaagctcc cgttacctcg ccgcgatcgt tgagtcatcg gacgatgcga ttgtcgcgaa
  1442701 ggacctaaac ggaatcatca ccagctggaa tcgtggtgcc gagcggcttt tcggctacac
  1442761 ggccgaagac gttatcggaa aatcgatcac catcctcata ccccaggacc ggctgagcga
  1442821 ggagcccggc atcctcgaac gcatccgtag aggggataaa gttgaccatt tcgagacgaa
  1442881 acggcgtcgc aaggacggga gtttgataga catttcgctc accgtttctc ccgtcagaga
  1442941 tgctaccggg cgcatcgtcg gcgcttccaa gatcgctcgc gacgtcaccg agaccaagcg
  1443001 cgcggcagaa gcattgtcag atcgctttcg cgagcaggcg gcgttgtatc gcttcacgga
  1443061 aagagtgcag cgtaccaagc ggatcgaaga cgtcttcgag gccgcgctgg acgcgatcct
  1443121 ggaagcgttg agctgtgacc gcgcctccat tctgctgttc gatccctccg ggaccatgcg
  1443181 ttttgtggct tcgcggggtc tttcagaggc ctatcagagc gctgtcgacg ggcactcgcc
  1443241 ctgggcttcg ggcgcaagcg aacccgaacc gatcttcgtc gaaaatgtag acagtacgga
  1443301 catgtcgcgg gcgttgaagg aggccattgc ccaggagggt atcggcgctc tcggcttttt
  1443361 ccctctggtc ctggacggaa agctcatcgg caagttcatg acctattacg acgagccgca
  1443421 ccggtttgcg gaatccgaaa tcggcgtagc ggtgaccatc gcacggcaac taggtttcag
  1443481 ccttcagcgc atggaaaccg aaaatgcgcg ccgtcaggca gaggaacgct tgcgccgtaa
  1443541 cgaggcgaac gaaagagcgc gcgcaggcga attggccgcg ataatggaag cggtcccggc
  1443601 tctgatctgg attgcgcgca cgcctgattg ccacgtcatc agcggaaaca agagctctta
  1443661 cgaaatgctg cggctgccgc atgacagcaa cctgtctctg tcggctcctc cgggcgagcg
  1443721 ccccaccaac ttccgcgtat tctccggcgg acgcgcactg tcacccgatg aactgccggt
  1443781 acaaagggca gcacgcggcg aggaagtgcg gaacttcgag gaggaggtgt ggtttgagga
  1443841 cggaagctcc cgatatattt tcggaaacgc aacgccgttg cgtgacgccg caggcgaagt
  1443901 gatcggcgcc gtcgccgcct cggtcgacat aaccgagcgc aggcaggcgg aagaggcact
  1443961 tcaggaaagc gaacggcgcc tgcagctggc gctggatgct ggacatatgg gcgcctggga
  1444021 atggaacctt ggaacggatg aggtgatctg gtcacccggg ctcgaggctc tgcaccgtct
  1444081 cgagcgtggt agcttcggaa gaacgcttgc agatttcaag cgcaacgttc atccggacga
  1444141 tctccccttg atcgatcgcg agatagccaa agccgtcgag accaaaggag actaccacgt
  1444201 cgtctaccgt gcgcgcctgc tcgacgggac cgtccgctgg atggaagcct tcgcgcaatt
  1444261 ttcaccgagc aacggtccat cgaggcgatt gatcggcgtc tgcatggaca tcacggaacg
  1444321 cagggaggcc gaagcgcagc gcaatctctt ggtggccgaa ctcagccacc gcgtgaaaaa
  1444381 tacgcttgca atcgtcggct cgattgctcg acagaccttc tcgaccagtc cagacgcgcg
  1444441 cacggcgcac cgttcgttcg atgcgcgcat cagggcgctt gcgcaaacac acactcgcct
  1444501 cgccgaggcg agttggtccg gcgtttcctt gcagaccgtg ctgtacgacg aactggcccc
  1444561 ctatcaggat gacggcagga ccaatgtcaa gcttcaaggg ccgacagcaa tgttgccgcc
  1444621 caagcatgcg ctcacccttg gcatggcggc gcatgagctt gccaccaatg ccgcgaaaca
  1444681 cggggcactt tccgtcaaga gcggcaaagt ggatatcgag tgggtggttg acgtggacac
  1444741 cgatcggctt cggatctgct ggcgcgagtc gggcgggccg cccgttgtca cacccgcgca
  1444801 caatggattc ggtcgactgc tgctcgagcg tgtcctggct tcggatcttg gcggcgaagt
  1444861 gcacctcgaa ttcaagccgc aggggctggt ttgtacgatc gatgttccgt atccgcgcgg
  1444921 ggctccggga tgaatgcggg caaccgatgc cgggtgctcg tcgtcgagga cgagtttctt
  1444981 gttgcgcttc agatcgaagc cgatctcctc gcggccggct atatggtggt cggccccttc
  1445041 accagccttg cccagtctat ctccgccgcc cgcgcgcacc ccttcgacat tgcgaccctg
  1445101 gatctcaatc tgcgtgggga gttcgcctat ccgcttgtcg acgaactcgt cgatcgcaag
  1445161 gtgcccgttc tgctgttgac cggctatgcg gcgcacgatc tgccggaacg ctttcgtgca
  1445221 ttgcctcgtc tggcaaagcc tttcgacggc acgcagctca tccggaagat aagcgacata
  1445281 taccccgtct catgacgccc cggccggcgc gttggccggc cagggcgtga tcattaatca
  1445341 cccgccgcga agttcacatt tcggtgggca ggaaatggga aaccggcacc tgcagggcgc
  1445401 cggcgacgcg cttgagcttc gctggactga agtctgtgcc gttctcgatg tcgttgattt
  1445461 cgacgacggc gaggccgcag gtgacggcga gatcctcgat gctgtagccg accgcttcac
  1445521 gcgcggcctt gacgcgagcg gcgatgtcgc cgttcgggac aagcgcagct tccttgtggg
  1445581 caatattgga gtgtgaaata gacataaatg tctccttctc ttggcatgaa aattcttgcg
  1445641 aattttgctg ttgagtacgg gtcgacaagc gtcgctgcat ggttcctgca ccgaaattgg
  1445701 ttcaaggaga acatgcagca gattaaagtg ctgcaacgac cttctgcgtc tgaagacgcg
  1445761 gcgctgcagg acgacggtaa cgttttatgt catcgctgta acatggacaa gccgaaatcg
  1445821 agcttgtaca ccgccggcgc cagcgagggc ctggaaggct tcccagaatt ctccggttgc
  1445881 aaagaagtga ttcggcgcgc aggcggcgaa gcgtgaccgg ccgccggttg cgcggatgtc
  1445941 agaggccgag cgaataacgc tgggaacctg aatatcacaa aagtttactg gaatagataa
  1446001 gccgccccta cttgtccccc aatgccgccg caccgcatga aatcgcaaat acaatcaatg
  1446061 ggtcgcgtgc cgcgcaaccc gggcggccat taccgcatcc cgccgtgagt acgccttgtg
  1446121 tcagccgccg cggcccaaaa tccggttttc agcaggcgtt attgtccata cattcagtat
  1446181 atgttgattt ctaatttagc tttatttcag cacttttgga tttcgagcgg cgtgtttgct
  1446241 ttcagaccgg gcattgcccc gtggcgcctg ccctcaccgg cagattgttc cagccgcaga
  1446301 gtcagcctcg aaaatatgaa ggccgcctcg tctgttcctg cagcgtgcag gggcaagcgc
  1446361 cagatatacc gacctgactg atttggcatg cggtgcatgc cgagatggag gaaactggac
  1446421 atgaaaaacc agaccggcaa aaggaagaag gatcgaacgc ccgccgcacc accggaagtc
  1446481 agcaatattt ggcagcagtt cgagatgatg cgccacgcct tcgccgcctc gccggtactg
  1446541 aagcccatcc tgtggctgac caccgggagc ttcgccgtca tcgtcgccac cgcgatcggg
  1446601 caggtcgttc tgaaccgctg gtaccggccc ttcttcgatg cgattgaacg gcgggacatc
  1446661 aacagtttct tttatcagct catgttgttc gtcgcgatcg ccggcgtcct cctggtcttc
  1446721 aacgtcggtc agcagtggct caatcagatg gtgcgcttga agctgcgcga gggactgaca
  1446781 ctggatctga tcaacgaatg gatgcggcct cgacgcgcct ttcgacttgc aaatgccggc
  1446841 acgatcggag tgaacccgga tcagcggatg caggaggatg cggggcatct cgcagatctt
  1446901 acgaccgggc tcggtttcgg cctcgtgcaa tcctcgatca tgctcatatc tttcgtcggc
  1446961 gtcctatggt ccctctcagc cggttttgcc ttcgatatcg gcggacagaa gctcgaaatt
  1447021 cctggttata tggtgtgggc ggcaattctc tatgccggtt cggcatcgtg gttgagctgg
  1447081 ctggtcggac gccgaatgat cgtcttgaac ggcgagcgct acgcccgtga ggccgacctg
  1447141 cgcttttcca tgatgcatgc caacgagcat atagacggca tatcgcttgc gggcggagag
  1447201 gccggcgaac gccggcgcct gcaactcgat cttgcttcgg tcctcgtcgc cacacgcaac
  1447261 atattccgcg ccgagatcaa tcttgcctgg gtccaggacg gctacggctg ggtcacggtc
  1447321 gtcgccccca tcctcgttgc cgcgcccgtc tatttcgcgg gaaacatcag tttcggcggc
  1447381 ctgatgatgg cggttggcgc cttcaaccag gtgcattcgt cgctcaaatg gttcgtggcc
  1447441 aatgtcagcg cgatcaccga ctggcgggcg acgctgctgc gcgtcgcggc cttccgtcgc
  1447501 gccctcgtcg cggcggatac cctgcatggc gacgaaaaac gcatcgaatt cgtcgagaac
  1447561 gacagggatg tgatgacgct tgataatctg gaggtcgtct ccccctcggg cagaaccagt
  1447621 ttggccgagt cccggatcga aattgccccc ggccagaggg ttaacatcat cggtgatcca
  1447681 catgccggga agacgctgct tttccgggcc gtggcggggc tatggccctg gggaagcggc
  1447741 cgcgtgggaa tgccggcggg cgaggccgtg gccttcattc cacgcgcacc ctatttcccc
  1447801 cgtggccggc tcagggatgc gcttgcctat ccgcacgctg acgaatttgc ggattcagtc
  1447861 ctcgtaagcg cactttcaaa ggtcggtctc gatcatctgg caacctcgct gaacagagag
  1447921 gcacgttggg agcgtgaact cggcgaagat gatcagcgcc tcctggcatt tgctcgactg
  1447981 ctggtgcaaa agccccgctg ggtggtcatc gacgaggcgc tcgagagcat ggacagcgat
  1448041 gcgctgaaac gcgcgctttc gattttcgag gtcgacctgc gggagaccgc ggtcatcaag
  1448101 atcggccgca cgccgcggaa cggcgggttg ttttcccgcg tgattcgtat cgtcaaggac
  1448161 gcggatgccc cagccctcaa accggtgcgc ctaggaggcg gggtcgccga attggagttg
  1448221 gcggcgcgca gcgcgccttg aggtctgcgg gtatcaaacg ccccgcttat tgccccaaat
  1448281 gaggacatgc aactgcggca gcacccgcgc ctcgaaccat ccgtcctcaa ttgtcgcgtc
  1448341 gaccagccaa cgcatccgct ccatcacacc ctcgagatcg atcggcgcat ccttgtcgtc
  1448401 ggagggcggc ggcgtatggt tgccaggctg cagatagacg ggcagatgcg ggtggcgcgc
  1448461 ggctgcagcc cttgcatagg cataatccgc ctcgtcgaaa accacgaact tcaacacggt
  1448521 ctgcggcttg cctgcagcca ttcgcaggca gacgtcgaag gcctgccaat ccgtctccat
  1448581 cccgctcgag ggcggttttg gactgagtac cagcacatcg agttcggcga accactcccg
  1448641 ggcgatcgag ccctgcgtct ccagcgcgaa ccggtagccg ttccggtgcc cgcggccgat
  1448701 cagatcgccg aacggctgta tagccggatt tccgcccgac agcgaaacca tcaccgcctc
  1448761 gccccgggac agccgaacga tttcctgcca gaccgcctcc gtcgacatcg cgtgccattc
  1448821 atgccggtaa ctgctctcga cggcatgcag gctgtcgcac caggaacagc ggtaatcgca
  1448881 gccgccgctc ctgacgaata ccgtcgggag gcctatcagc actccctcgc cctggatcgt
  1448941 cggtccgaat atctcgctca cgcggatctc gtcggatcgg acgttcgtca tggccggtat
  1449001 tccgcccagg tctttgccgt ctcgctgacg cgaacggccg ttgtttcgaa aagacgagcc
  1449061 ttgcaccatt cgtagaaatg ccgtgccaga cattccgccg tcacccggtc gtgcccgagc
  1449121 acgtcgttca ggtggcggtg gtcaaaggcc tcatcgatat acgtcttcag aggcgcaagc
  1449181 tcgtgatagt cgcgcacgaa accatgctcg ttcaacgttt cgcccgaaag ctcgacctcg
  1449241 acgatgtagt tgtgcccgtg cagccgcgcg cattgatgct cgggaggcag gttcttcaac
  1449301 tgatgcgagg cggagaaatg gaattccttg gtgatgcgaa acattattcc acctcctccg
  1449361 ctacgaagga tccggtcacg gtgacccaga aatcggcatc gtcatacgcc gtcggatcgg
  1449421 cgacatcggc caggtgaaag gcttcccgac gctcgacgca ggtgccgcaa cgcccgcaat
  1449481 ggcgggcacc gcccttgtag caggaccatg tctctgcaaa gggcgtgccg tacctggatc
  1449541 cgtcggcgac gatctccgcc ttcgccacgt tcacataggg cgcatagagc cccacatccg
  1449601 catatccatc gagcgcatgg ttctgcatcg cctggaaagc atcgatgaaa cccggccggc
  1449661 agtcgggata gatgaaatgg tcgccgccat gcacggcggt cgcgaccgca tcggccttgc
  1449721 gggctgcggc gaccccgaag gcaatggcga gcatgatggc gttgcggttc ggcaccaccg
  1449781 tggtcttcat cgtctcttcg gcatagtggc cgtccggcac gtccacctcg tcggtgagcg
  1449841 cggaaccggt gagatggcgg ccgatctccc ttatgtcgat gatctggtgc ggaacgccga
  1449901 ggcgtcgggc gcaaacggcg gcgaaatcca gttccttgcg gtgccgctga ccgtagtcga
  1449961 acgacaggag gcagacgagt tcctgttcag ccgcgacctt gtgcgcgagc gaaacggaat
  1450021 ccaatccgcc ggagcagatt acgattgtct tcatgacagc tgtccttgtt ttgaccgggt
  1450081 aggctgcgac cggagtgtta cctgagcgcc ttttaggtca aagtggacgg cttgtgaatg
  1450141 gcccgtgcgg aaagacacga agtttgtctc acggccggta aggccccccc aacgccgggc
  1450201 tttagccgga atgcgtcatt gcgcgcccgt ccatgttctc gtaacgttcc ggtcggctga
  1450261 aaaggcaacc atatgcagca ggcaaattca cacgatcgac acctggacaa catccccttg
  1450321 gcggtcgggg tgatcatcct gaccgttctg gcactttcgt tgggcgacgc gctgatcaag
  1450381 atgtccagtg gcagcttcgt catctggcag atatttgtca tccgctcgat gattgcgatc
  1450441 cccgtgttgc tcctgattct gatcatggcg gcacccgaca cgttgcgtat gccagatgac
  1450501 cttgtctgga tcattttgcg cagtctgatg ctagtagcaa tgtgggtctg ctattacgtg
  1450561 tccctaccaa agttgacact ttcggccgct gcggctgcct attacacgct gcccatcttc
  1450621 atcacccttt tttccgccct gttcatcggc agcaagattt cgcaaaaagg ctggctcgcc
  1450681 gtctttgctg gattttcggg cgtggtcttg atcctgcgcc ccaaggccgg cgacttcaac
  1450741 gcatacgctg tcttaccgct tgcctcggcg atgctctatg cggcagcgat gatcctgaca
  1450801 cgcaccagat gccgcaacca acacccggtc attttgtcgc tggcgctgaa cgccgccttt
  1450861 gtcatcgtcg gtgtggcggc cgcgagcctg atcccgctgc tacccgacac ggcacggcag
  1450921 ggctttttgc ttgcgccctg ggcggcgatg ggatggagcg aatggatttc gatgatgctt
  1450981 ttggctggtg taatcctgac cggcagcatc ggtgcggcta tcgcctatca gaacggcccg
  1451041 cctgccatga tcggtgcctt cgacttcgct tatgtcggat tcgctgtcat ttgggggatc
  1451101 gttttcttcg ctgaggtgcc ggacacgagt tccgtactcg gcattggctt gattgtcagc
  1451161 gcggggatat tgtccctgcg ccaataaccg tatcgtcagt tagtgactgg ttccgtcacc
  1451221 aaactctcgc cacgtcacgg atctccaaag cggccgggcg aacgcagcac cttcccgcat
  1451281 gccggccgcc agcgcgacca ggcaggtgct tgaacgatcg tttcactgcc tcactgaaac
  1451341 agcgaaacga aacattacgc gctggcctca tccctcgctg aggatgaggc ccttcgtcag
  1451401 ttccagcgcc tgccgctcaa acagactgcg atagatgccg cccttgacgc ggatgagcgc
  1451461 gccgtggtcg ccttcttccg caatgcggcc gcgatcgaac accagtagcc ggtcaagcgc
  1451521 gcgcaccgtc gaaagacggt gtgcgaccac cagcgtcgtg cgccccgtca tcagccgctc
  1451581 catcgcctgc tggatcagca cctcagactc cgaatcgagg ctcgacgtcg cctcatcgag
  1451641 gatgaggatc ggcgcatccg ccagaaatgc acgagcgatc gccacgcgct ggcgctcgcc
  1451701 gccggaaagc ttcaccccgc gttcgccgac gagcgtggcg tagcctttcg gcaattcggt
  1451761 gatgaaatca tgagcgctcg caagcctcgc cgcttcctcg atgtcacgct gcgtcgctcc
  1451821 cggccgtgca taggcgatat tctcggcaag cgagcggtga aacagaatcg gctcctgctg
  1451881 cacgatggcg atctgctggc gcagcgacgc ctgcgtgaag tcggcgatgt tctgcccgtc
  1451941 gatgcggatc tcaccggcat tcagatcgtg gagacgctgg atcagcttga tgaacgtcgt
  1452001 cttgcccgag ccggaatgcc cgacgagacc gacgcgttcg cccgccgcta tgcttaccga
  1452061 gaagccctgg taaagtggtg cacgatgcgc tccgtagtga aaggtcacgt cgcggaactc
  1452121 aatcccgcct tcggtgatgc ggatgggctt tgcgccgggg cggtcctcca cgccgagcga
  1452181 ctgatcgtga atggcgacga gttcctccat gtcgttgatc gagcgctgca ggttgcggat
  1452241 atgcatgccc acttcgcgca gatagccctg caggatgaag aatgaggtca gcacgaaggt
  1452301 gatatcgcct gcggtcgcct gccctctggc ccagagaagg agagcgaagc cgatcaccgc
  1452361 ggcacgcaga accagcagca ttgcaccctg tgcggtgccg ttgagcgtac cgcgcgacca
  1452421 ggtgcgccgg gtccggttct cccatttgcg cagaaccttg gcgaggcgcg cgtcttcgcg
  1452481 tccctccgct ccgaaagcct tcacgacggg gttgcagctg accgcatcgg caagcgcgcc
  1452541 gccgagccgg gtgtcccagc tattggcaag gctcgccatc ggcgccacat agccgagcga
  1452601 cagggaaacg gtgacgacga taaagacgat cgagccgaga ccgatgatca cccccatcat
  1452661 cggccagtac caggccatca gcgccgtgga accgaccagc atgaccacgg acgggaaaag
  1452721 cgccacgagg agcgtgtcgt tcaacagatc gagcgcccac atgccgcgcg tcactttgcg
  1452781 gaccgtcgag ccggcgaagc tgttggcgtg ccagtcactg gaaaaccgct ggatgtgatg
  1452841 gaaggctgct gccgcgatgt cggacatcat cttcagcgtc aggctgacga tccccatgaa
  1452901 ggtcacgtgc ctgagcacga tcgcgccaag cgacaaggcc atcaacatca tgaaggccgc
  1452961 cattgccgca ttccaggcga tctcgtcact ggccgccccg gaaaccacgg catcgaccag
  1453021 ccggccggaa tatagcggcg tgagcacatc ggcaagcgtc gaaaacagca ccgcggtcag
  1453081 aagagcggcc agccgcaccg gttgcctctt ccaatgtgcc caggagaatc ggaaaacgct
  1453141 gagaaaggcg cggttgcgcg ccgtgaaacg ggtgaatgcc ataggatttg cccggtggcg
  1453201 cgagcgcacc ggcctcaaaa tctggaaaac atgaaaatgc cgtcggggaa aagatcagaa
  1453261 cggcatcagc ggatcgccgg cttctgaata agaagcggtg gggcgacgac gattcctgat
  1453321 tgctgcgaag aagcgcgaac gcttacgtca cagggtcagg atcgtgggcc cgccccgtag
  1453381 ggagaagaaa atgcctgcat cgtaacctcc ctgatctgac tgccggagga ctgcttatag
  1453441 ttgaggtcag cgcgcacgcc aagcgtcggt attgcgtttc atgaaaagca gaacggggat
  1453501 gctgcatgtt tgcaacactt tcccgagtgt tgcggagcat gctcaattgc gttgcggtat
  1453561 gagaagccga ttatggccgt gtccaggcgg cgaagttgtt gaatatcccg cgattttata
  1453621 gaactttcac aatctgttgg aaatttcgcc gctattcatt gcgaagcctg ccacgttttc
  1453681 aaagttcaga atcatccttt gaggttgccc gtgcagaaca acaacatcct cgtcgtcggc
  1453741 ggagccggct atataggctc gcatacctgc ctccagctcg cggcaaaggg gtaccaaccg
  1453801 gtcgtttacg acaacctctc caacggtcat gaggaattcg tcaaatgggg agttctcgaa
  1453861 aagggcgata ttcgcgacag gcagcgcctt gacgaagttc ttgcccggca caagccacgg
  1453921 gcgatcctgc atttcgcggc catgatcgag gtgggggagt cggtcaagga tccggccgcc
  1453981 ttctacgaca acaatgtcat cggcaccctg acactgcttt cagcggcgct ggcggcgggc
  1454041 atcgatgcct tcgttttctc ctccacctgc gcgacctacg gtctgcccga cagcgtgccg
  1454101 atgaacgaga cgcacaagca ggcgcctatc aatccctatg gccgcaccaa atggatttgc
  1454161 gagcaggcgc tgaaagatta tgatcattat aaggggctgc gctccgtaat cctgcgctat
  1454221 ttcaatgctg caggcgccga tttcgagggc cgcatcggcg agtggcatga gcccgagacc
  1454281 catgcgatcc cgctggccat cgatgcggca ctcggccgcc gcgagggctt caaggtcttc
  1454341 ggaaccgact acgacacccg cgacggaacc tgcgtacgcg actatatcca cgtcctcgac
  1454401 ctggcagatg cccatgtacg cgccgtcgac tatctgctgg agggcggcga gagcgtcgcg
  1454461 ctcaatctcg gaaccggcac cggtacaacg gtgaaggaac tgttgaacgc gatcgaagac
  1454521 gtggcaggcc ggtcgttcaa tatcggctat gcggagcgcc gcgaaggtga ttcgaccacg
  1454581 ctggtggcga ataatgacaa ggcacgcgag gtcctcggct gggagccgca atacgatctc
  1454641 gcagcgataa ccaggtctgc ctggaactgg cattcgcgca gaaaccaggg cgcctgactt
  1454701 tcccagagcg gctggccgcg ctgtcggaac gtttaggcag cccggccatc ttttcgaaat
  1454761 cgtcctattc cgccgcacgc ccggcaaggc ccccggcaac ccgccgggcg ttgccccgcc
  1454821 gcatcagcgg gcgctcgagc atcatgtatg ccgcaatccc gatgagcgtt cccgaaagga
  1454881 cggccatgaa catcgttgcc ggcgcgccga gatcgatctc cagggccacc ttagccacga
  1454941 ccgatatcgc aaaagtgtgc cagagataga tggaatagga ggcgtcgccg agaagcgccg
  1455001 gcagcggcac cctccgtacg cagccattcg cctccagcga aaggacgccg aggacgagca
  1455061 gcacggcaag cggtccggtt atcagctcgt cgaaaggcag agcgagcaag ccgatgagag
  1455121 cgaagccgcc gagcgagcag gccatcagag cggaaccgac cgccaacggc ggtaccctgc
  1455181 ccttcagcca gaactccgcg atgatcatgc cggcgacgaa ctcaagaatg atcggccgcg
  1455241 tataggtcag catcaacgta ccgtcgaagg ttgcgacacg gccggcgatg acaagcgcca
  1455301 ggaaaaggcc ggacatggcg ggcagccgcc agttgcgcgg caagacgagg gagccggcga
  1455361 agaccaggta gaagagcatc tcgaaattca gcgtccagcc ttgcacgagc acaggccaga
  1455421 cttctccgct gctcggagag cgcgccggca cgaagaacag cgacgccagg acatgttcca
  1455481 ggctaaggac cagattggga aacagacccg ccagcgcccc cgcgaccatt acggcggtcg
  1455541 cgagccaata gaccggcacg atgcggcgcg cacgatccct gatgaattcc agtggtgtca
  1455601 ccggccgacg gtcgctgatg acccacatga tgaagccgct tatgacgaag aagacgtcga
  1455661 cgccggcggc accgatcgtg aaatgatggc cggttttctc cgccgcgtgg aagaaaacaa
  1455721 cggcgagtgc cgccgcggcg cggagatatt gtatgccgta gatcgtcttc aacggttttc
  1455781 cccgggtcgc tgcatcatcg gagtgaaggc ccgtccgtag ggtgcgggat gaagctgcgg
  1455841 cggccaaggc aatgccgcca cccggcggcg cgggatcgtc agcttcccag cggtgaagta
  1455901 caggaggaag gaaccgatat ggtagggcgt gaggatatcg atctccacga aggcgcgcac
  1455961 caaaagcagt gctccaacac cgaagaggac catcgattcc gggtcgcaat cctccgaaag
  1456021 caggcgcttc agctgcccga agaaagtcat ggccagcacc attgtcagca gaacaagccc
  1456081 gatgagaccc gtctccacag ccgtctctat gaaggtgttg tggaaatgaa agccggcgcg
  1456141 cgagccgata tagaactcct cccatagccg ctcggcttcg gagaagccct gcacccaata
  1456201 agcctgatag ccgatgccga cgaggggcga cgcctttgcc gcctcgatgc cctgctgcca
  1456261 gagataggtg cggccggtca gcgtcgagtc cttgccgaaa gcgccgagga tcatatcgat
  1456321 gccgccggcg tagattattg ccacggcagc cacgccgccg aacaccgatg cggcggtgaa
  1456381 gaggatcttt ctgctcgcgg gacgcaaggt cgtgatcgcg cgcatgccga ggcagaggcc
  1456441 gatgaccgct gccgtcgtca gcaccgacgt tgccgattgc gacatgagga ggcaataggc
  1456501 ggcaagcaat ccgccgcccc ctgccgcgcc catccagagg cctctttcgc cgagaacaaa
  1456561 aacggcggcg aaagcgaaat agatgccgag cgaggcgtag aagcccaact ggttcttcga
  1456621 tgcgaacgca ccgacaaagc tataggtgcc atccagggga tcgtaatgat acgagccgaa
  1456681 gagcagcgaa tagaggagca cgatcgcaac gcctgcaatc atgccgcgcg tcagcgtgcg
  1456741 gatgtcgatc gtacgcattg cgatgagagc gcagacgacg tggctcagat attgtattcc
  1456801 cgtccgcagc gacagcgatg gcgccgccga ccagaagatc gtgaggcagg cgaagatggt
  1456861 gaacgacagg atccagagat agctggcata gttgccgaga acctttcggt agtcgacaag
  1456921 gaccagcggc agccacaggc cataataggc gagaatcgaa acctgtccga agcgcgccga
  1456981 ataggcgaag acgaagaccg acagggccaa ggcgaaggtg ccgaagacgt cattcgctcc
  1457041 aggtctgaca aggctcgcct tggatattct catgccggcc tcaccgcatc gccgccaatg
  1457101 ccgtattcac tttgatgacg tccccaggca gcactggggt gttctcatcg gccgcgatct
  1457161 cggtcggctt cccatccttg tcgcgaatga tggaataggt gatctgggct gcctgctgtt
  1457221 cgagctgggc cgcgtccgcc gactgcagca gcgcctctgt catgagatcc cggctggtgc
  1457281 cgagcttcaa ggccagcgta tcgagttcgg cttcggtgtt ctgcagttcc tgcgcaagtt
  1457341 gcgcatccca gtcgttgcgc agattcgttt cgtcctgcgc cgccttgctc gcatcctgtt
  1457401 tcgctttcag cgatgcggtg tcgatatcca gcagggaggc ctgcacgtcc gccacccgtt
  1457461 gctcgaggga aagcttgcgc tgactcagcg caagcccttt ctcggcaagg ctgtcgacct
  1457521 tgtcgcgatc ctcggtggca agctccaatt ggcgcgcctg cgtttcagcc ttctttgcga
  1457581 gcgcttcgat ctcgctttga agaagggacc tcagatcggc gagagcatcg agctgacgct
  1457641 tctggcgctt gtcgcgcgat tccataaggg cggtttcgct ggcgagcagt tcgtcggcac
  1457701 ccggtacatt cttgagctcc tcgggcatcc cgatcgagtc acgcttgccg atttcggcct
  1457761 gcaggcgcgc tcggcgaatg aggagacggc tgcgttccgc aacctgtaca gccgattccc
  1457821 cgctcgcatt gatgtagtcg cgtgcaaacc gctggccgtt gtcggcccgc cgcagccctc
  1457881 ccccgagact gacggccttc aggaccgtca tgttgggagc gtaaggatat tcgccaggcg
  1457941 tctgaacctc tccggagaga tagaccggtc gatattgcgc catctccacc gatgcggagg
  1458001 gccgatccct gagaccgaag agcttctgca tctttacgcc gatctcttcg gccacttcgg
  1458061 ctgtcgtctt gcctgaggca ggcagttcgc cgacgaaagg cagggaaatg cttcccgatg
  1458121 caccaaccgt ataatcgccg ctgacggcgg accaatcgcg gaccgcacct tcggcggtct
  1458181 gccactcggc gacgcgaacc cggagtttgt ccataacgcc gagccgatat tcgtcggcgc
  1458241 gcgccagcga tgtcgcggaa gcggcgagag ccgccatgag caccaggcgg gttaaacagg
  1458301 aagccatgcg ggaaccagcg gatgcccctg gtagtctgtt cgattgcatt ttgggatatt
  1458361 tccgttgctc agcgttaccc gtctagggct cacgccaaga tttcagtagc tgccgcggga
  1458421 gaggcagacg gcaggaatcg ttttgaatac aatgacaaaa tcgaccaaaa gcgaccagtt
  1458481 ctggacatat tgcgtgtcga aagcaacgcg cgtggcgtag gacacatcat tgcgcccact
  1458541 gatttgccag aggcccgtca gaccaggccg cgagcgcaga taaaattcgg cagccgaatc
  1458601 gtagagttca agttcgtctt cgaccacagg acgcgggccg acgacactca tttcaccgcg
  1458661 gatgatgttg aggagctgcg gcagctcgtc gagactgagc ttgcgcagga cggccccgac
  1458721 cacggtcacg cgcggatcgt tctgaagctt gcgagtggcg caccattcct cgtaagcgtc
  1458781 gggattggcc ttgaaatagt cttcgaggat ctggtcaccc ctctccatca tcgtacgaaa
  1458841 tttaaggcac ttgaacgact ggccgttgtg accgattcgg cgatgcccat agaagacacg
  1458901 gccgccgtcg gagaacttga cgagggccat gatgagcagg aagagcggac tgaagagtag
  1458961 aagggccacg gaggcggcaa caatgtcgaa actgcgtttt gccatacccc cgatcggtcg
  1459021 gactgccccg gtatcatcgg ggataaaaaa cggcgaactg gccgagcgag tcgcggactt
  1459081 catagagatg actccattta ggttggcgat tgtcggtccc gtgggacgcg ggctgatcta
  1459141 acgcgagtgt atggtcagat tttgtttttt gaaggcggaa taatggcaag ccgcagcgtc
  1459201 cttgcccgga gagggatttc agccggcgcg atcgcgaaat attgcaaaga gttaattttg
  1459261 gcgagcggca aactagcgct aggatagttc ccgattgcat cacgcgagga aaacatcgtt
  1459321 atgattaatc acttataata ataaagtatt gtaatagacg catcattctt gcactgcggc
  1459381 gggccccaag cggcggcgaa agaaattgac gcgcggcaag tttgaccggt tttttgcatc
  1459441 gcaacatttt attgcgccgc acatttttgg aaccgtgctg tgccaatggt tgtaataaaa
  1459501 gttgatcgaa aaatgtgccg gatcgcgaac tgggagaggc agcattccag accgagtgcc
  1459561 caatgcccca acaaaattag gggtcgccca gctgacggag ctgctcgccc ttcattacgg
  1459621 gtggaaagga ggaacttatc gccggttgca cccgtttgat tcgtgcggaa tagagcgaat
  1459681 gcctaaagac gacggaaaga attccgatgt atgctcaatt tcaacaatgc agcgtttcca
  1459741 ggttgaagag aaaagcggcg gctaatatag tgggtaggca ggaggagagg gcaacaactc
  1459801 ttatgacgct tccaatcgca gacccgaagg cagggtagcg ccatgtttgc accgcgtgtt
  1459861 tttgtaagca tgatcggcgc cttggcggca tttgccgttg caacctatta tttaaacggt
  1459921 tcgctcgcct cgacggcgat ccagaccctg atctgtgccg tcctcatgca ggtaggttat
  1459981 tttgccgcca tccttttcct ggtatggaag gaagcgcgcg agcgccgcag ggtttccttg
  1460041 cagaagccgt tcgtgacggc tgaggctgcc aatgacgaga agcagtccgg aaaagtcccg
  1460101 ctgcgccggc tgaaccggcc tcatcatttc aattcctgag aagctccgcc caggcgtata
  1460161 actccttcgc acctgcgaaa aaattcgttt cccgacgcgt ttgcgacatg atcgccgggc
  1460221 atggtccctt cagcgtcgcg ccgctggcgt ggcttggata gctgtagaac cttgaattgc
  1460281 tgcatgattt cgtgctgagc aatccgttct cgacgaacat gcaaacgccg gaatcgcgcc
  1460341 ggcggataac ccgctggagg gctcacatga ccgcagccgt gccgacaaat gtctgcataa
  1460401 tcatcgccgc gaagaacgcc gccgacacca ttgcccgtgc ggtctcctcg gcgcttgccg
  1460461 agccggaggc ggcggaagtg gtcgtcatcg atgacggctc gaccgatgac agtgctgcgg
  1460521 tcgcgcgcgc tgcagatgat ggctccggcc ggctgaacgt cgttcgcttc gaggaaaatc
  1460581 gcggcccggc ggcggcacgt aatcatgcaa tcgagatttc gaagtctcag cttcttggcg
  1460641 tgctcgacgc ggatgatttc ctcttccccg gccggctgcg ccagttgctt tcgcaggagg
  1460701 gctgggactt catcgccgat aatatcgcct ttatcgatgc cgcgcaggcg gcaaacgcac
  1460761 aagccagtat cgatcgcttc gcccctgctc ctcggctcat cgatcttgtc ggcttcatcg
  1460821 agggaaacat ttcgcgccgc ggcgtgcggc gcggagaaat cggattcctg aagccgttga
  1460881 tgcggcgcgc cttcctcgac cagcatggcc tgcgctataa cgagactttg cgcctcggcg
  1460941 aagattacga cctctacgct cgcgcgctgg cgaagggcgc acgctacaag atcatccaca
  1461001 gctgcggcta tgccgcggtc gtgcgcggcg actcgctgag cggcagtcat cgaaccatcg
  1461061 acttgaagcg tctctatgag gccgatcgtg caattctcgc cggaaacaag ctgagcaacg
  1461121 acgccgaagc agccctacgc cgacacgagc gacacatccg ggaccgctac gaactgcgcc
  1461181 attttctcga tctcaagaac cagcggggct tcgctcgtgc aatcagctat gccctgaccc
  1461241 acccagcggc tctgccggcg atcctgggtg gcatccttgc ggataagacc gagcgttttc
  1461301 gtccgtcccg cgcgccggct ccccttgccc tcggcggaac gggcgatgtc cgctatctgc
  1461361 tcgaggcctt ggccatggat cagcctcaaa aatagtcccg gcggatgcct tcgagcacca
  1461421 cctggaaacg ctccttgcgc tccgccagcg cgctgtcctt gcttaattgc ggcgtggcac
  1461481 ggctggcatg ccacagcgcc agggccgagg gggcggcgag aacgcgcttt gctgcaccgc
  1461541 gcaaggaact gtgtcggggc gctcgctccg caacgacgac atctccgtca atattccgtc
  1461601 ggttgggatc ctccggccgc ggctccttcg gctcgaaatc cattccccag aaacgggagc
  1461661 ctttgatcac cgcttccgct cgcgtcgaca ccggcacccg ccgcggtcga taagtgacgc
  1461721 cgagggtctg cgcccaatcg ttccatttga agctgttgat actgttcgat gtgctgaccg
  1461781 cggtccaggg aacgcggaac gcgtcggcca gaatggcgcc gtgcatggac tcggcgacga
  1461841 tcagttccga ttgcgcgatc tttcgaatga cgtccttcgc ctccccgcgc ggatcgatgt
  1461901 agttgagccc aaccacatca cagatcgcag gccacaaccc ggcgatcgcc gattcccagt
  1461961 gcggcacgaa gcttcgcttg tatatcttgc ctagatcctg aaattcaggg agatccgcaa
  1462021 ccattacggc aggatcgatg atgccgagct ctggcgccac gccgactttt gcagccgtta
  1462081 acggaccccg gaccgaccga atatcccatt cctgacgatc gctcatatcc ggcagcgtgc
  1462141 cgtagccgaa tccgctgccg atgacgagct tgtgcgtccc ctccggaaga agggcgcgat
  1462201 tcaagaccgt gccaaccccg acgagcagcg tctcggggtg aatctcgcga aaacccggca
  1462261 acaggaagtc ccagagccac aggttgaggt catcaccgaa atttccgtgc tgggattccc
  1462321 aataatacgg cttcatgacc gtctccgttt gaagtgtgtg gggcgacacg acagccaccg
  1462381 gcgtcgaatg ccatcgttcg ctttccgggt ctcgccagtg ctaacccggt caggtcggaa
  1462441 gtgaggttca gcgagacagc ttgccgacgg caagttcggc ggcgctgccg agcaatcgcg
  1462501 ggtctcgcca cagccagcgg gcaagaagat cgaattgcgg caatttcctg ctctttatcc
  1462561 ggcgtgcctg gctccagagc gcctgccgac gcgccgtatg cttgtaagag cgaatcgccg
  1462621 ccattgcctt gggcctgttc tgatatcggc cttcgagcgt gtcgagtgcg acccatgtgt
  1462681 tgaactgctg cttcaggaac tgaggcgaat cgttgtcgat cgaatgaaag atgttcagtc
  1462741 cctcgccgcg gactgcaccc gccgcatcgc aaagcacgac gcgcttggct gccagtacgc
  1462801 aatcgcagaa gaagagtacg tcttcggccg caagcttgag cgcggcttcg aaacgggcgg
  1462861 tttcgaaaag cttgcgccct atgaccatgc aggacatgtg gaggaagctc caatccttca
  1462921 gcatgacgtc ctgaagctcg ggaagttcga cgacgagcgg gtcttccgaa aggcgcgtga
  1462981 ccatctcgct tttttcgagg tccgcgaccc cgaaatgata atagaaggcg tcgccaccgg
  1463041 tgatcgaagc ccaatagcag tcggcgtcga aacgcgtcat gctctgatag gcattcagga
  1463101 ggtgatccgg cgtccagaca tcgtcggaat caaggaaagc gacgaactcg cttcctgcag
  1463161 gaacattgtc gaggccggta ttgcgcgcgc cacccggccc agcattgggc tggcggacga
  1463221 ccgtgatgcg cacttcctgc tccgaagtaa gcccgacaag ctcgtccgca accggatagg
  1463281 gggactgatc gtcgattatg agaacgtgga aatcctcgaa cgtctgggca aaaacggatg
  1463341 ccagcgcccg gcggaggata cccggctcct tttggtagta cggaatgaca actgtcagct
  1463401 tcgccatctt ttcgcccctg cggcttctct aaaaagagtc tgcgtggtct cctcccatcg
  1463461 ggttgcggcc gtatatctag agtttgtcct ttgcatttcc tccctcaaag gacttcacgg
  1463521 aatcttcttc aatgacccca accgttaacg caaaaaccgt aacgcgcaat gtcggctgga
  1463581 gcgttctctc caagacaggg acattcgggc ttaaatttgt cacggtaccg attctggcgc
  1463641 gcattctgtc ccccgaggaa ttcggcgcgg tcgctgtggc gctcacggtg gtgcagtttc
  1463701 tcgcgatgat cggcggcgcc gggctcacct ccgcgctcgt catccagcat gaagaggaaa
  1463761 tggaaaccgt acactcggtc ttctgggcaa acctcgcgat cgcgctcatg atggcgcttg
  1463821 gattgttcgt ttttgccgag ccgctggcca cgctgctcgg cgcgccggag gcaagttacc
  1463881 tgctcaagat aatgagcctg ctcatcccgc tgcagctcag cggagacgtc gcctattcgc
  1463941 tgctggtccg gcggatgaat tttcgcaagg atgccgtctg gagcatgatc tcggaatcac
  1464001 tcggcgccgt gattgccgtc ctcctcgcac tgcttggttt tggcatctgg tcgctgatcg
  1464061 cccagctttt cgtctcggcg ctggtgcgcc tgtccgggct ctacgctgtt tcccgatacg
  1464121 ctccgcgctt cgtcttctcc atgcaacgcg ttgtggcact gagccgcttc agtttcggga
  1464181 tgatgggttc cgagatcgcg aatttcataa ccttccaatc accgatgatc gtcatatccc
  1464241 gttatcttgg gctctccgac gctggcgcct attcggcagc aaaccgcttc gccagtatcc
  1464301 ctaatcaggt cgtactctcc gccgtcatgg gcgtgctgtt tcccaccttc ggccagatga
  1464361 tgcatgatcg cgagcggcgc tcgcaggcgc tgatgctcag cacccaggtg acgaccgttc
  1464421 tgctggcccc gatgatgttc ggcctttggg cgctggccga gccggcgatg ctcgttcttt
  1464481 tcggaagaca gtgggcctat gcctggcccg tcctcggtct tctcgcgctt tcaaagggca
  1464541 ttctcactcc ctgcagtaca ttcatcccct atctgaaggg tgtcggaaag ggagcggtcc
  1464601 tgttctggtg ggcgctgatt cgggcggccg cgacgacggg ggcggtcgcc tacggggcaa
  1464661 tcaacggttc gctgatcgag gccatgatct ggctgtgcat cgtcaatacc gttacgcttg
  1464721 tcggatattc atgggtggtt tttcgtgccg acgatacacc cttcctcaag gggcttttcc
  1464781 tatccagccg gccgatgatc gcagcgctgc tgatggccct tgtcgttcgt ttcatgctcg
  1464841 agcggttcgg cgcccacctt ccaaacgccg ctctccagat gatcgccggg gcggccatcg
  1464901 gcggcgcgat ttatacggtt ctgatccttc tgacggagcg atccctgttg cggaggcttt
  1464961 tggacatgat gcgggcacgc aaatcgagag ccgctctggc gggagccggc gagtagccgg
  1465021 acacgtctgg cttcggagga gcaccgccgg tccgaccggc cttttgttgc tgctacaaac
  1465081 gagccgcgga acggtttgcc tcatgccgcg tttccgctcc agtggcaaca acacggattt
  1465141 ttcgagatga aaggtattat tctctggttg atgggcgtgc ccctcatcgt cattatcctg
  1465201 ctctacatgt tcgttttctg aatgcgcagc tccgccaatc atccgactgg cgccgaagca
  1465261 agccgatttg cacgtggcag ggcttttccc catgcttttg acggatgtgg atggcaccca
  1465321 tctgggctag cctgttcggg ttggctgggc tggaagggga tggggcatga ccgccaccat
  1465381 aagcgctagg atcatctgcg gcagatgcgt gccctgcgcg ttgccaaagt tccggagcgc
  1465441 ttattgttgc ggcttcccag ccgctcgcct ttccgcggcc gaaggcgctg gaaccgcgga
  1465501 tcccatcatt ggcaagcccg gtcggagcca atttcgttga aatcgcgagc gcgagcgctt
  1465561 ccaatttaat taataaggat ggtgtataga cgatgtgaac cgaagccgag ttgctagaga
  1465621 ccgcagacga gagacgatga tcttagaatt ctggatcctg tgcgctattg ctactgccgt
  1465681 tatcgcggcg gtcagaggcg gtcatagtct gttttggttg cttatcggct gcatcctcgg
  1465741 gcccatcgga attgttgcag cgatcttcgt gccttccctg aaagcgaaag acccgtcggt
  1465801 tgccgcaaaa cggcagggtg aggtcgatga gctcgcaagg ccgctgcgcg aaaccgacac
  1465861 aaaggcggtc tcggtcaagt cgaaagatca ttagagcagc cggcccgggt tgcccgctcc
  1465921 ccgagtcggg aatttgctct tcggtcagaa gaatctcttc actgatcccg gcgccgctga
  1465981 cctcgctccg cttgccccaa cctcgccgca tttggcgcca cgactaatcc attcggaacc
  1466041 ggtgccgaaa aatattacgt actgccggaa agatttcagt ctctgaaatt caactaccgg
  1466101 ttaccccaag tttttgtggg agacaggttc cgcaacatgc ggcgaaacca ggatttatcg
  1466161 cgcaggcagg ccccctccgg aacgccggca atattgcggg cgctcgccat tttggtgcgc
  1466221 tgcagcatga ttcggttcaa ttttctgctg caacgccata ttttttctaa gggcgtgccc
  1466281 tagtttctct tctgcgggcc gcggtctgct ctgttgaaac ggctgccgca aggcgctgcc
  1466341 cgatagggag tgactgaaat cgtgagtatg gacgcgaatg tctcggcgcg catcaacctg
  1466401 atgcgtattc tgctgatctc cggcatcgta ttcgtgcacg tcccgtacaa tccgcagtgg
  1466461 agcccatttc tgggcaacta cggcatgctg gactggattc gcgtcttcct cggcgaaagc
  1466521 ctgttccgga tcggtgttcc ctgcctgagc gcgatctccg gctatctcct atttcggcgt
  1466581 ggcctggccg gtttcgacta ttggaagaca ctgaagacca aggcgcggac cgttctcctg
  1466641 ccgttcctta tctggagcgg ctcctttttt gtggtggtct atgccatcca gtaccagggc
  1466701 ctcggcttcg gctatctgcc agacacaatc agtgcgacgc cgcgccagtg gctgagcatg
  1466761 gccttcgcgc tcgaggcaac gcccgtcaac ctgccactgt atttcctgcg cgacctcatg
  1466821 ctctgtgtcc tgctttcgcc cattctggcg ttgctggtga gccgttatcc gcgcgtgacg
  1466881 ctgcttgctc tgctcgccta tgcgatcctg ccgctgccaa acgggatttt tctcaagaag
  1466941 tccattttgt tcggcttctc ggcaggcatc tatgcgagcc tgcatggcgt gaacatcaaa
  1467001 gcgcttgatc gctatgccgg gccgatcgcg gccggattcc tggcgatagc cgtcgcgatc
  1467061 gccgtcggcc tctattacac cggtccggat ttcccgctgt ggctcgacat ggcgctccgc
  1467121 ctgacgtcga ttgccggtat catcggctcc tgggcaattt cgcaactgct cgttcgtacg
  1467181 cgcctcggcg gcaggttggg gcgcggaagc gggctaagct tctggatctt ctgcggtcac
  1467241 tatccgttgc tcgtcctgtt ctggatgatc tggaaccgca ccgggctcag ctactacccg
  1467301 ctcttctact tcaccgcgcc gctcatcgcg attgcgatcc tcgtcgcgtc tcacaatctc
  1467361 gtacagcgcc tggcgccgga cctgcttgca gtgcttaccg gcagccggac gggtgcgaaa
  1467421 cgaatacccg tgccggcgcc gcaaggcgcg caagctggct attcgccaca gcaaaggtaa
  1467481 cgaccatgac aaacgatcgc tatacacgca tcgcccgtct cgccttcatc gcaacgcttc
  1467541 ccttcgttgg gcttgtcagt gccgccgcgg cgcaggaagg cgccaacggc acctccttca
  1467601 aggacgattt cgacagtctc gatacgcgca tctggtacgt ctcggacgga tggaacaatg
  1467661 gcgggcacca gaattgcact tggtcgaaga aacaggtgaa aacggtcgat ggcattctgg
  1467721 agctgacctt ccaggagaag aaggtaaagg accgcaattt cgcctgcggc gaagtccaga
  1467781 cgcgcaagcg cttcggctac ggcacctatg aggcgagaat aaaggcggcc gacggctccg
  1467841 ggctgaactc tgccttcttc acctatatcg gcccggccga taagaagccg catgatgaaa
  1467901 tcgatttcga ggtactcgga aagaatacgg cgaaggtcca gatcaaccag tatgtgtcgg
  1467961 cgacgggcgg caacgaattc ctcgccgatg ttccgggcgg cgccaatcag ggtttcaacg
  1468021 attacgcctt cgtctgggag aagaaccgca tccgctacta cgtcaatggc gaactggttc
  1468081 acgaagtaac cgatccggcg aaaatcccgg tcaacgccca gaaaatcttc ttcagcctct
  1468141 gggggacgga cacgctcacc gactggatgg gtaccttctc ctacaaggag ccgacgaaac
  1468201 tgcaggtcga tcgcgttgct ttcacggcag ccggcgacaa atgtcagttc gccgagtcgg
  1468261 tggcttgcca gctcgagcgg gcagcgtccg aataatgctc gtctctcggt aattattcaa
  1468321 tttgttgcag tgcacaaaga attgaactaa gctcggcctc gggctgggca agaaaacgga
  1468381 cgttttcatg ctgcagatac tctatctggc acaggatctt gccgatcccg cagtgcgccg
  1468441 gagaaccctc acgctcgtca cgggcggcgc acgcgtgacg ctcgccggct ttcgccgcgg
  1468501 cgccaatccg ctcgcagcca tcgacggcgt cgagcccatc gaactcggga ccaccgccga
  1468561 cggccgtttc ggccagcgga tcggtgccgt cgtccgcgct tgcatgtctc tgaaaagcag
  1468621 gctcgcacac gttcccaagc ccgacttgat catcgcgcgc aacctggaga tgcttgcact
  1468681 agccaggagg gccgtcgccg ttttcggcgg cacggttccg atcgtttacg aatgcctgga
  1468741 cattcatcgc ctaatgctcc gccaggacat ggtcgggcgc actttgcgag cggccgaagg
  1468801 ccagctcggc aaggacgttc gcttgctgat caccagctcc ccggccttcg tcgagcacta
  1468861 ttttcgcccc atttccagca tcggcgctcc gccgatgctg ctcgaaaaca aggttcttga
  1468921 actcgatggc atctccgaac ctaaagccgc accggcggta tgcccagcgc ccggtgcgcc
  1468981 ttggaagatc ggctggttcg gggcgttgcg ctgccggagg tcactcgcac ttctggccga
  1469041 gttctcgcgc aggatgaacg gccgcttcga ggtcgttctg cgcggccggc cagcctactc
  1469101 cgagttcgag gatttcgacg gcttcgttac gaacgagccc ttcatgcgtt tcgcaggcgc
  1469161 ctatcgcaac ccagaagacc tcgcagatat ctatggcgag gtccatttca cctgggcgat
  1469221 cgacttcttc gaggaaggcc agaattctgc ctggctgctg ccgaaccgtc tctatgaagg
  1469281 ctgccgccac ggccgagttc ccatctcgat gaaagggacg gagactgctc gtttcctatc
  1469341 cgtgcggggc atcggtctcg ttcttgaaga agccgacgcc gacagcctcg acacagtcct
  1469401 cggctcactg tctccgcaga gctatgccga cgccgcagaa cgcatcagcc gctgcaatcc
  1469461 cggatcctgg atattcagcc gcgccgattg cgaagccctg gtgcggcaac tggcggcgct
  1469521 taccgtggag acgcggcagc acgttcccat agtcgcgacg gcgggggccc gccacaatga
  1469581 aggtggtttc ttatgaactc cgaagaactg acgtccacgt cgagccttat cgtcataccg
  1469641 tgcctcgacg aagcttcgca tatcgaggcg ctgatcgaaa agctgcgtcc ggcgctcacg
  1469701 cctttgaacg cgcagatcgt cattgccgac ggcggcagca ccgacgggac gcgcgatatc
  1469761 gcccgccgtc tggctacaga ggatccgcgg gtgctcttcc tcgacaatcc gaagcgcata
  1469821 cagagcgctg caatcaatcg tgccgttgcg gaactgggtg ccgacagcga ctacctgatc
  1469881 cgcatcgacg cccatggcac ctacccggac gattattgcg aacggctcgt cgaggatgca
  1469941 ctggcgaccg gcgcggattc ggttgtggtc gccatgcaga cagtcggttt cagcaccttc
  1470001 cagaaggcga cggcattcgc gcagaactcc aaactcggca atggcggttc caagcaccgc
  1470061 acgggcgccg tcggccactg ggccgaacat ggccatcatg cgctgatgcg catcgaagcc
  1470121 ttcaaggctg ttgggggata tgacgagtcc ttcagccaca atgaagacgc ggaactcgac
  1470181 tatcggctcg gcaaagcggg ctaccggatc tggatgaccg atagaaccag tatggtttac
  1470241 tacccgcgtg cgaagatcgt ccctctgttc cggcaatatt tcggctatgg ccgcggccgc
  1470301 gcaaagaact ttctcaagca tcgcgccatg ccggggctga ggcagatggt gccgcttgcg
  1470361 gtcgcacccg tcgttttcgg agcgcttctc gcgatcgtca actggatggc cgttttgcca
  1470421 gccggcgttt gggcaggggc gtgccttggt tacggcgtct ggatggcgct tggtcagcga
  1470481 aacccctatg gtccgctggc cgcggttgcg gctatggtca tgcatctcgc ctggtctgcc
  1470541 ggtttctggc gcgagctcct cgactttcgc cgcagggtgg cgtgatggcg agcgaaaccc
  1470601 tgcacataga tatcggcgtc tgcacgtatc ggcggccgga gcttgccgaa acgcttcgct
  1470661 cattggcctc gatgaaagtg ccggagcgta cagatattcg cgtcatcatc gccgacaacg
  1470721 atacggatcc gagcgccaga ggtctggtcg aaggccttcg gccgcaaatg ccgttcgaaa
  1470781 tcctctacgt ccattgcccc cattcgaaca tctcgatcgc gcgcaattgc tgtctcgata
  1470841 acagcacagg agatttcctc gcctttctgg acgacgacga gacggtatcg ggcgactggc
  1470901 tggtccgcct tctggatacc gcgcgcggca ccggcgctgc cgccgtgctt ggcccggtaa
  1470961 aggcgcacta tgcggctacg gctcccggct ggatgcgcgg cggtgatttc cattcgacgc
  1471021 tgccggtctg ggtgaaggga gaaatccgca ccgggtacac atgcaatgcg ctgctcaagc
  1471081 gcgatgcgcc ctcgctcctc ggccggcgct tcaagctggc gctcggcaag agcggaggcg
  1471141 aggacacgga cttcttcgcc gggatgcacc aggcgggcgg aacaatcgcc ttttcgccgg
  1471201 aagcctgggt ccatgaaccg gtaccggaaa acagggcatc gcttgcctgg cttgcgaagc
  1471261 ggcgtttccg ttccgggcag acacatggtc gtcttttggc cgaaaagtcg aacggcctac
  1471321 gtcaggcctg gaacgtttgt cttgcctgcg ccaaatcagg cttttgcgca actgccgcgc
  1471381 ttctctgctt tccttcggca gcgaggcgct accggtttgt acttcgcggc gtgctgcatg
  1471441 ccggcgtcat cagcggcctg ctcggactta aggaaatcga gcaatacggc gcccgtgagg
  1471501 tgacctcgcc atgagcgctc ctctgagcat ccccgacgtc acattcgtcg ttgccgccta
  1471561 caattcggca gacacgatca tgcgcgcaat cgaaagcgcc ctgtctcagg aaggcgtcac
  1471621 ggtcgaagtt atcgtggtcg acgactgctc tacggacgcg acgccggcac ttgtggcagc
  1471681 gatccgggac ttgcgcgtcc ggctgatcgc gctcgaccgc aaccgtgggc ccggcggcgc
  1471741 acgcaacgcc ggtatcgggg cggcacgcgg caagtggatc gcggttctcg attcggacga
  1471801 tacggtccgg ccggaccggc tcaggcgcat gatagagcga gcggattcgg ccggagcaca
  1471861 gatcgcggtc gataatattg atgtcgtttc gctcggcggg ggcagtctca ggatgttccc
  1471921 cgaagcgcag ctcgcccgca tgccgcagct tacacttccc gcttttatcg ggtcgaacat
  1471981 actctttcga tccgagcaca atttcggcta catgaaaccg gtcttcgagc gccgcttcct
  1472041 cgaaaatcat ggacttcgtt tcgacgagac gctccgcatc ggcgaggact atatcctgct
  1472101 tgcatcggcg cttgcctgtg gcgggcgctg cgcggtcgag ccctcggccg gctatatcta
  1472161 tcatatccgc gagggctcca tctcgcgtgt gctgcggctc gagcatatag acgccatgat
  1472221 cgccgccgac gaggcgtttc tgcagcgctt cgcgctcgac gcccaggcac aggaaatgca
  1472281 gcgcaaacgt atgcgcggct tccgtcaggc tcgctccttt ctggtccttg tcgatcagtt
  1472341 gaaaaagaga tcgttggccg gcgcgttcaa aaccgcactg gccgacccgc tcgcactccg
  1472401 gcatctcggc atgccgattg ctgcccgatt gcgccgcctt gccgcgcgat tgctgcatcc
  1472461 tccgtcccat gcccccatga cggcggtgga acgatcgccg ttgggcgacg acccccacac
  1472521 aagcaaagga tgattcaatg aaccatgtca ggaccgtcag aaaagcagtt attccagttg
  1472581 caggcaacgg gaccaggttc cttcccgcga caaaggcagt gccgaaggag atgttgacga
  1472641 tcgtcgaccg gccggtggtt caatatgccg tggacgaggc ccgccaggcc gggatcgagc
  1472701 atattgtctt cgtcaccagc cggaacaagc aggtgatcga ggatcatttc gacgacgcgc
  1472761 cggagctcat ctcttcgctt tcgcgctctg gcaaaaaggc tcagatttcc gaactcgaag
  1472821 ccatgcttcc ggcagcaggt tcggtcagct ttacgcgcca gcaagccccg ctcggcctcg
  1472881 gacatgcggt gtggtgcgcg cgcgacctga tcggcgacga gcccttcgca cttctgctgc
  1472941 cggacatggt ctcgttcggc gcgcgcggtt gccttgccgg cctcatggac ctttacaacg
  1473001 aagccggcgg caatgtcgtc ggtgtcgagc aatgtgcgcc cgaggaagcg tcgaaatacg
  1473061 ggatcgtcgg caagggcgag acggtccggc acggtttcgc cgtgaccgag atggtcgaaa
  1473121 agcccgccgc cggaaaggca ccgtccaact actatctcaa tggccgctac atcctgcagc
  1473181 cggaaatctt ctcgatcctg gcacaccaga cgcgcggcgc cggcaacgaa atccagctga
  1473241 ccgatggcat gctgacgctt tcgcagtcgc agtccttcca cgcgcatccc tatgaaggcc
  1473301 gtaccttcga ttgtggcgcg aagcagggct tcatcgaggc caacgtcgcc ttcgcacttg
  1473361 cgcgtgcgga tataggcgac ctcgtttttg aatccgtccg cgacatggtt ctgtctcacg
  1473421 aaagccgcat ccgcgcggca taaacggcgg cttccgacgg ttcttgcatg ttgctcagaa
  1473481 gcgcacagca gtctgagcaa catgcagaag caacatcgta aagcgcgcaa cgtgaactct
  1473541 atcgacgcgc tctgagagac cgccggtaca aggaccggaa aagcagatga acagaacggc
  1473601 ccccatgaaa caaagaagcg ttcccttgag cagcatcatg cccagcgaag aacagtccga
  1473661 cggctttatc gaccttgacc ggcttgtagc cgccgtcttc cgtcgcgccc ggctcgtgac
  1473721 cgcattcgtc gttctcttca tcgcactggg ggccgcttat ctcctgtttg ccacgcccta
  1473781 ttacacgtcg atgacgcaga tccttctcga cgagaacctg tccaaatacg ccgaagagga
  1473841 gcctgtcccg gtaaacagcc agatgctgga tacgcagatc gcaagtgcgg tcgaaatcct
  1473901 caagtcgggc gaactcgcgc ttcgcgtcgt cgacaagctc aagctttcgg aaaacgaaac
  1473961 catcctcaat ccgccgcgct cgcccgtcga cgtcgtgaag gaatggctga agacggccac
  1474021 cggactcttt gcgggcggac ctgaagtaac cgaggcggca gcgcgcaacg gccggcggca
  1474081 gaaagctgcc gcgatcatcc agcaatcgct tgcggtcgag cgtgtttcgc gaagctcggt
  1474141 cgtcgccgtg gcttttcgct cgagcgatcc ggtgcttgcg gcgaccatcg cgcgtggata
  1474201 tgccagcgca tatctgacag accagctgaa cgccaatttc gaagctacgg aacgcgcatc
  1474261 cgtctggctg caggaacggc ttacggatct tcagcaacgc tcgcaggccg ccgcgctgga
  1474321 agtcgcacac tacagggccg agaacggttt gacggctgcg cggggcgagt tgatgtccga
  1474381 gcagcaaatg gccgacctca acagccagct catcgttgcc caggccgaca cggcaagtgc
  1474441 ctccgcccgc tacaatcagt acaagtcgat cgtcgaccag gggccggaaa acgcagtgaa
  1474501 gaacgccacc atctcctcca aggagggtga caattcggta atccgcgacc tgaggacgcg
  1474561 ctatctcacc gtcggtaagc gcgagcgcga agtctccgac aatttcggcg ccgaccaccc
  1474621 gcaagcggtc tcgctccgca ccgaacagga ggatgtggcc cgtcagatct accaggaact
  1474681 gcagcagctc actgcaagct ataagaacga atacgaggtc gctcagtcgc gcgaggcatc
  1474741 gctcaggaaa agcatccagg ggattgccgg caaaacctcc gactcgagcg agcaactcgt
  1474801 gcaattgaga gagctggaac agaaagccgc ggccctgaag acgctctacg agtcttatct
  1474861 cggacgctac gaacaggcga ctcagcagca aaccttcccg atcgccaagg ctcgtgtcat
  1474921 ttccgaagcg ggcgtgcccg tgtcaccgtc gagcccaaaa aaaaccatga cgctggcgct
  1474981 ttcggcggtg ctcggcctga tggtcggcgg tgcatacgcg gccttcctcg aattccgcga
  1475041 acggaccttc cgcctggagg gcgacgtacg ctcgatcctc ggccatcgtt cgttcggcta
  1475101 cgttccgctt ctcggcacgc gcatcaagaa gaaggcgcaa ctcgttcacg cacatttcgg
  1475161 ttcggtgaag agagccgacg aagcggtgga caatacgatg ccgttccagc gattgtcgcg
  1475221 catcgtggtc gatgcgccgc ggtcgacctt cgcggagacc tttcgcaacg ccaagcttgc
  1475281 ctgcgaccag atgctggcgg gcagtgaaag ccgcgtgatc gccatcgcat cggcccttcc
  1475341 ggatgagggg aaatcgatca ttgccgcaaa cttcgccgcg cttctggccg cgagcggcaa
  1475401 gcggaccctg ctcatcgatg ccgacatacg caagcctggc ctgacgcaga tgattacgcc
  1475461 tgccccgcgc accgggctgg tggaaacgct gaccggagaa gccacctggc ccgccgggat
  1475521 caaggtggac cagcgtacga aactggcaat ccttccggcc ggcggtgcat cgcaccagcg
  1475581 ccaccagagt aacgagctgc ttgcctcgcc gggcatggcg aacctgatcg agaacgcgcg
  1475641 caacgccttc gactatgtcg tcgtcgacct tgcggcgctc gcccccgtcg tcgacgcgaa
  1475701 agcctttgcg ccgctggccg acggcatcct cttcgtggtc gagtggggaa gaacgccttc
  1475761 gcgcctcgtg cgcgatctgc tcaactcgga accgctgatc aattcgaaag tgctaggtgt
  1475821 gatcctcaac aagacggaca tgaacgagct gggcaaatac agcgatttcg acggggcaga
  1475881 aaagtaccgc caccgctacg gcaaatacta catagaaaac agtttcacgg acaatcagaa
  1475941 caccgccgct tgatcaaagc gcagtgctcg cctgaaggta gccgacgcgc gggtgcttgg
  1476001 gtctgctcac actaatcctc ccaccagtgg tggaaatggt ggactggccc ccgcccctgc
  1476061 ccgatcttca atcggccgga cgcggaaatt gcggcatgca gataggtttt ggcggcgttt
  1476121 gccgcttcga ccagcggcgc acctcttgca aggccggcgg caattgccgc cgacagggtg
  1476181 cagccggtgc catggtcgtt ctgcgtctcg acccttgccg ccggaagacg gacaaaagtc
  1476241 tgtccgtcga agaagaggtc ggttgcctgg tcgttcttca ggtgtccgcc cttgaccagc
  1476301 accgaatgtg cacccgaccg catgatcgct tccgcctggc gcgccatctc cgcctcctcc
  1476361 tcggcaaccg cgcgccccgt tatgagtgcg gcctcggcga gattgggcgt ggcgacgatc
  1476421 gccagcggta gcaactcgtc tatgagcgcg gcaacggcgt ccggccgaag aagcgtgtcg
  1476481 ccggaagtcg caaccatcac cggatcgacg acggccagct tcccgaaccg gcgcaatcca
  1476541 tcggcgatgg cggcaatcgt ttcccgacgc gagaccatgc cgatcttcac ggcgcccaca
  1476601 tcgagatcgg agaagacggc gtcgatctga gcggacacga tctcggccga aacatcttcg
  1476661 accgcagaaa cgcctttggt gttctgggcc gtgatcgcgg tgatcacgct ggcgccgtag
  1476721 acgccgagcg cagaaaaggt cttgagatcc gcctgaatgc cggcgcctcc gcccgaatcc
  1476781 gatccggcga tggtaagagc gatcgccgtc atgcccgtcc atccttttta cgagaatgcg
  1476841 tcacgcttgc tttgagtaga gggggaaagg acgtcatcga tcggtctccg gacgggatat
  1476901 caagaaaccc aggctgagcg acgaaaggcg aacttgccgc gggcggccct caatccgttc
  1476961 ctacgccggc atgacccgga tcaggttcaa gggtccggtt caacaccatc tcagcaccgc
  1477021 ccggtgctcc cctcggaaag cgctatctat gaggtgcggc agcgccatgt caacgcgacc
  1477081 tcgcaaaagc tattgagact ggcgcttccc gctggccggg tcgtattttc cgccaagcga
  1477141 cagactacga tgcgcttatt tctcctgtag gcgccagccg ctcgtttcct cctcgaaatc
  1477201 ggtagcaatt gcgctatggt tagcgaaatt ttgcctaaca aaggaacgag ccatgagcct
  1477261 gcgcattaac gacactgccc ctgatttcac tgccgagaca acgcagggta cgatcaactt
  1477321 ccatgaatgg atcggcgacg gctgggctgt tctcttctcc catccgaaga atttcacccc
  1477381 cgtctgcacg acggagctcg gcgcgatggc cgggatcgag ccggagttcc ggaagcgcgg
  1477441 cgtaaagatc atcggtatct cggtggatcc ggtcgaaagt cacaccaaat ggaagaacga
  1477501 catcaaggtg gcaaccggct tcgatgtcga ctatccgctg atcggcgacc gcgatctgaa
  1477561 ggtggcaaag ctttacgaca tgctgcccgc cggcgccggc gacacgtccg agggccgaac
  1477621 gcctgcggac aacgccacgg tgcgttcggt ctatgtcatc ggcccggata agaagatcaa
  1477681 gctgatcctc acctatccga tgaccacagg ccgtaacttc aacgagatac tgcgcgccat
  1477741 tgactcgatc caactcactg cccggcatca ggtggcaacg cccgccaact ggcagcaggg
  1477801 cgacgacgtc atcatcacgg cggccgtttc caacgaagat gccgttcaac gcttcggctc
  1477861 cttcgacacc gtgcttccct acctgcggaa gacgaaacaa ccgacggcct aaacatagcc
  1477921 atccaggcca gaaggaaaaa tgatgggcgc accgaatctg caagattggt gcgcccttgc
  1477981 tccattttac gaatgtattg ccttaactcg ctttggccac gccgatgatc tctgacaaaa
  1478041 ccccgtgtaa cgcatcacga tagccattgc gtgccgacgg cccgctttca tccgaggtca
  1478101 tgactacagt cagactcaag gtcgggacga cgtagagcat ctggccgcca tagccccacc
  1478161 cataatacac agcctcgtcg ccgatccggc gcatgaacca accatatcca taaccgtcac
  1478221 ctgtgaaacg cgactccgtt cgcggctgcc acgaaagctc gatccaatcg gccgggacga
  1478281 cctgccgtcc ctcgggagtg cggccgcgat tacggtagag ttcgccgaag gcaaggagcg
  1478341 atcgcgcgct catcgccatc tggttgccac ccaaatagat accttgcgga tcgcgatccc
  1478401 aggccccgat gcggaaacct tccaatggag cgagccattc gcgcgcaagc tccagtgtcg
  1478461 acttgccgcc gaccttggtc agtattgccg aaagcagatg cgtggaagcg gtcgaataga
  1478521 gcatccggcc tccgggctcg tcgtcgaagg gctgtgccag ggcaaaacgt acccagttgc
  1478581 ggctcgagac ccaacggcca tagttcggcc ccgacatccg ccccaggccc gcttgcatcg
  1478641 agagcaggtt gccgatcgtg atctcgttga tccgcgggtc gggctgcggc gggagttccg
  1478701 ccttgaggag cgccgcgatc ttctgctcgg gcccgtcgag cagccccttg tcgatcgcaa
  1478761 tccccaccag tgcggatatg atcgacttgg acgccgattt tatgttggtc gactccgatg
  1478821 tcgtgtggcc tcgataaccc ttttccgcga tcgtctcgcc gtgctgggca acgataaccg
  1478881 ccctcagggg cttcagctcg tccctggtcg ccaggctcgt caccagggtc gcgacggccg
  1478941 accgatcctg cgcggctgcg accgggagga aactgaggag tgcaaggaaa atgacgacaa
  1479001 gcctgatcat gcgttccacc tagtgcgtgg tttcctttga tcgtacgcga ttaagggaca
  1479061 aaaatcaggc ggcaagtcaa agtgctgcgg cgacggtagc gccaagggaa acgagcccag
  1479121 accgacccta aaatgcggat aagggtagtt cggcctttcg ctgctgtttt cctacctttc
  1479181 ggtcttgcca acgaaatcgg ccgggttctg gtacttcacg gtttgcaggt gctcgcagta
  1479241 gagaaccagt tcaccttcgt tcttgaagac ttggtagctg gcgcgaatga ggccgaggtc
  1479301 tttgtaacgg ggcaccttct ccatgttggt ccggatcgtg taaatcgtgt caccgatgaa
  1479361 gaccggcttg ataaagcgca gcttgtcgta gccgtaggaa aaagcgttca cgcagttggt
  1479421 cgcgacgagg ccgagaccgg ccgagaacac gaaggcgccg gcgacgaggc gacggccaaa
  1479481 tattccttcc cgttccgcga acatccgatc ctgaacataa ggatggatat cgatgacaag
  1479541 tgtattgaag agatggctat cgctctcgcc gatcgtccga cgcagcgacc ggatacgctg
  1479601 accgatgggc caatcttcat agaaccagtt ttccgcgttc cacacgggca gagcggcgtg
  1479661 atcgtccggc atgtcggcgg gatgcgtcga cgaaactccg acggtgggca taaactcatc
  1479721 cataatcagc acctgcgtaa aaaggtcggt tgaaaagcgg atctcccggc ctctgcgccc
  1479781 atggggggga gaagcctggt ttggtgctat tggaccgcgg acgtcccata gaccagatca
  1479841 ggcaaccaaa gcgacagttg cggaaacatg ctcagcacga tgagaagggc catcatcatc
  1479901 gccagatagg gcagcacctc gcgtgcatag gccatcatcg gcaccttcag caccatggac
  1479961 gaaatataca tcagcccccc aaccggcggt gtaataccgg caatggtcag attggtgatg
  1480021 aagacgatgc cgaaatgcac gcgatcgatg cctacgccgt cgatgagagg aatcagcatc
  1480081 ggcgtgagga tgatcagcgc cgccgatccc tcgattgccg tcccgatgac gatcagcagc
  1480141 acgttgatga ggagcagcat caggagcggg ttgtccgtcg cttcgccgag ccagcccgac
  1480201 atggcctgcg gcacctgctc ccaggcgaga tagaaaccga aggctgccgc cgcgcagatc
  1480261 atgatcatca ccacggctga atcgcgtaca gcttcggcca aaacctccgg aatctggcgg
  1480321 acggtgaact cccggtagcc gaacacagcg acaaagagca cgtacacgac gaccacggca
  1480381 ccggcttcgg tggtcgtgaa aagaccgtac cgcgtacccg cgaagatcac caccgggatc
  1480441 gacagcgccc agaggccgtc gatcagcgcc cgggtcgcct ccgcgcgggt ggcgcgctgc
  1480501 ttgcgcagcg gtttgtagtc acgcttgcgg gcgatgaaat aggtggtcac catcagcccg
  1480561 gctgccagaa ggaggccggg caccaccccc gccgcgaaga gccggccgat ggaagtctcc
  1480621 gccagaaagc cataaacgat caggccgatg gagggcggaa taaggctggt gatgatggcc
  1480681 gccgaggacg tgatgaccgc agcgaaggcg cggctatagc ctctttcaga catctcgacg
  1480741 ccgagcgttt tggcgagcat cgccgcatcg gcattcgcag acgcagtaag gccgccgagc
  1480801 aaggtgccga gtaccgtgca catctgcgcc agcgcgccgg tcatgtggcc gaccagcacg
  1480861 tctgcaagcg tcaacaaacg ccgggtgatg ccggatgcgt tcatgataca gccggcaagc
  1480921 acaaatagcg gcagggccaa cagggatacg gattgagtgc cctccgccac ttcttgcgcg
  1480981 aagttggcca gcgggatcat gtccatattg atgagaaaga aggccagcgc cccgatcgcc
  1481041 atggcccagg tgatcggcgt cgacagcaag aacagcacga cgaccagaag cgaggggccg
  1481101 gcgagatgca acagggtcat atcagcgatt ccggatttcg atgcagccgg acagaccaag
  1481161 gcctttcggc gataaggtgc tggaaaagca ttccggcaga agcgagcgac agcggcgcgt
  1481221 aggacagggc gcgcgacagg tcgagcgcga tcgtatgcac atggcgggac gtccatgcct
  1481281 gccaggcgaa aaggatcgtc atgaccatga agaagagcgc cagcagcaga tagttgaacc
  1481341 aggcgactgc tttctgccag ccgtcaggca gggccgcgac aagcacatcg attgcggcgt
  1481401 gggtgccgag acggacgcca gccaccgcgc cgaagaacac gagataggca aaggccatca
  1481461 tagccagttc ataggtccag aaggccggct gagggaatac gtaacggctg gccacccccc
  1481521 agaggatcga gaacacgacg acgattagcg ccacgacgcc gaccgcctca tcggcgcggc
  1481581 gcaggctgat gagggggata gtctcctccg gcgagcgtga gatttccata atgcctcgaa
  1481641 ctgttgaagg gctgacggag cgggccacgg ccgcgcaatc gagaacgcgg ccgcgcctga
  1481701 acggaacttt tattgcttca tcgccttctg tacctgctcg tagatgccgg gcgttatatt
  1481761 cggaaccttg tcgtaggcgg cccgggaggc ctcgatgaaa gccggaatgt cgacatcggt
  1481821 cacgatctcg acgccggagg cagagagctg ctttgcatag gcgtcatccg tttccagtgt
  1481881 catctgcgtc aattcactgg cgatcgcccg cccttcctcg aggaggatct tttgaaggtc
  1481941 ttcgggaagg ccgttgaaga actggctgga ggctacccag gcggtgaaca tgatctgatg
  1482001 gccggtcttc gaaatgactt tgcgggtctc gttcaatttc gccccggcta ttgagccgaa
  1482061 aggcccttcg gctgcgtcga cgacgccggt ctgaagcgca ttgtagacgt ccccccacgg
  1482121 caattccgtc ggccttgcgc cgtagttgcc gaaggtcgcc atcatgatcg gcgacgaggg
  1482181 tacgcgaatg gtcacgccgg cgagatcagc cggcgagcga accggcttgt tggaaatgat
  1482241 gtgacggtag ccgaagaggc cgttcggcat gatgatcttg ataccacgcg cttccagctt
  1482301 gccggaaagt tccttgtaga gatccgatgc gaagaggcgc tccgtcgcgg ccagatccgg
  1482361 atagacatag ggaccggcaa ggatagacag atccggaacg aactggccaa gctgaccata
  1482421 gtcggtggca ctgagcagac tcgcgccgct catgaccatc tcgttgacct tcttttgcgc
  1482481 accaagctga tcacccgtca tcacggtgat cgcgattcgc ccgccggagc gttcaccaac
  1482541 acgctcggcg taagtcttca tcgctttgat gatcggctcg ttcggattca cctgcgaggt
  1482601 cgagaaccgc aggctgtatt cctgcgcact ggcaatgccg cagaacgaca gggcagccat
  1482661 tgcggccgca gcgatcaggg tcttcatgct ctcctccttc ttccggactc cctgccggaa
  1482721 cgcacgatat gtgaataatc tattcacaaa tgaacttcta acgtcaagtg acgattgtct
  1482781 ctcagggcgc cgagatacgg gaaacggcac aatttcacac cgcaacggcc gtggatggtg
  1482841 cggcgcttac agtggtgctg tggcagcgat tctgtttcga acgtccgtga atggatcctc
  1482901 gggtcaagcc cgaggatgac ggcgggaggg gttggcccac gaaccagccg agcgacgtac
  1482961 gtgtaccgag ccgtcgatga tttgcatttt gcgcggtcgc gggtggtcgc ccgtcgtgga
  1483021 aaattgccgc aacgtacctc tctctatcgt gcccggatcg ctcgcctcgt catcctcggg
  1483081 caagccgagg gtcaagccct ggatagcggt gggaggggtt ggcccacgaa accggccgag
  1483141 cgaggtacgt gtgccgagcc ctcgatcatt tgcattgcag cgcggccggg ggcagtcgca
  1483201 cgtcatgcga agattgccgc aacgtgcctc tctatcgtgc ccggattcct cccgtcgtca
  1483261 tccacggggc gactccggtc gtcatccccg ggctcttccg ttgtcgttcg catactcctc
  1483321 cggtcgtcat cctcgggctt gacccgagga tccacacgca agcatcacaa cgacggtttt
  1483381 gctcgcatca gccgcgaaac gtataatcct caatcgactt ttccttcatc tcaatcgaga
  1483441 atccgggtcg ggacggcggc atataggcag cgtcgctgat gacgcacgga tccaggaagt
  1483501 gctcgtgcag gtggtcgaca tattcgatga cccggccgtc tttcgtaccg gaaacggcga
  1483561 cgtagtcgat catcgacagg tgctgcacat attcgcagag accgacccca ccggcgtgcg
  1483621 gccatacggg aagcccgtat ttggcagcga tcagaagcac ggccagaacc tcgttgagcc
  1483681 cacccatccg gcaggaatcg atctgcacga tgtcgatcgc accctcggcg atgaactgct
  1483741 tgaacatgat acggttctgg cacatctcac cggttgcgac cttgaccggc ccgatcgcct
  1483801 cgcggatctt gcgatgcccg gctacgtcgt cggggctcgt cggctcctcg atgaagaagg
  1483861 gtttggcgaa agcgagcttc tgcacccagt cgatcgcctc gccgacttcc cagacctggt
  1483921 tcgcgtcgat catcagatat ctgtcggggc cgatcacttc acgggcgatc ctcaaccggc
  1483981 gcatatcgtc ggcgagatcg cggccgactt tcatcttgat atggttgaag cctgcgtcga
  1484041 ctgcctcctg cgcaagccgc cggagcttct cgtcgtcata accgagccaa cccgccgagg
  1484101 tcgtgtagca gggatagccc tccttctcga gcgcggcgat ccggtcggcc ttgccggttt
  1484161 cggcccgccg caaaatctcg atcgcctcgt cgcgggtaag cacatccgtg atgtaacggt
  1484221 agtcgacgat gtcggcgatc tcttccgccg acatctcgct gacgagccgc cataccggct
  1484281 tgccggcgtc cttcgcaagg aggtcccaga tcgcgttgac gattgccccg gtcgcaagat
  1484341 ggattgcgcc cttttcgggt ccgatccagc gcaactggct gtcgctggtc aggtgccgcc
  1484401 agaagcgacc gggatgtttc agaatatctc caatgtcctg accgacgacg agatgccgca
  1484461 tggcctggat agccatgcag cagacgtcat tgccgcgccc gatggtgaag gtgaggccgt
  1484521 gccccgccag ccctgggcga tcggtatcga ggatgacgta ggccgccgaa tagtccgggt
  1484581 ccgggttcat ggcatccgag ccatcaaggc ttgcggaggt cgggaagcgc aggtcgaaga
  1484641 cgcgcaggtc tgttatgcgg gtcatatttg ctccgatggt cctgcagcgc cgcgcgtctg
  1484701 acagacgtgc aaatgagagg cgctgcagga atatgatgct gccgaatcag tcgtccgcgc
  1484761 gtacgcgttg tttctggctg ccgaggccct cgatgccgag ctctaccacg tcgcctgcct
  1484821 tcagatagcg cggtggcttc atgcccatgc cgacgcccgg cggcgtgccg gtggaaatga
  1484881 cgtcaccagg gtgcagcgac atgaactggg agaggtagga gacgagatag gcgacgccgt
  1484941 agaccatcgt cttcgtcgag ccgtcctgca tcgtctcgcc attgaccttc agccacattg
  1485001 cgaggttttg cgggtcctcg acctcgtcct tggttacgag ccacggtccg gtgggcccaa
  1485061 aggtgtcgca ggacttgccc ttcgtccatt gaccatgacg ctcggtctgg aatgcgcgtt
  1485121 ccgaaacgtc gtgaacggtg caatagccgg cgacataatc gagtgcctct gcttcgctca
  1485181 catatttcgc cgtcctgccg atgacgatgc cgagttccac ttcccagtcg gtcttttccg
  1485241 aaccgcgcgg caggatcagg tcgtcgttcg gcccgacgat agccgaggtg gccttcatga
  1485301 aaataatcgg ttccggcgga acggtcgcgc cggtttcggc ggcgtggtcg gaatagttga
  1485361 gaccgatgca gatgaacttg ccggtgcctg cgacgcaggg tccgagtctc ggattaccgt
  1485421 tgacggcagg cagcgcctcg acatcgagct tcgccagttc ggtgagcttg ctcggatcga
  1485481 gggcgccggc ggcgagatcg ggcacctggc cggaaagatc gcggatgatg ccgtcggaac
  1485541 cgagaagacc cggcttttcc tggcccggtt cgccataacg aagaaacttc atgtgctttt
  1485601 tccctgatga acgttcaaat ggtccagccg ccatctatgg cataggcctg acccgaggtg
  1485661 taagttgcgc cggcgagata tacggcgaga tcggcgattt cttcgggcgt tccgagacga
  1485721 cccatcggtt ggcgggagat gaaggccgca cgcgcagtct cgtagtctcc ctgcgcccgc
  1485781 atgcggctct cgagcgacgg gctttcgacc gttccggggc agattgcgtt gcagcggatg
  1485841 ccgtcaccca cgtaatcggc agcaacggct ttcgtcagcc cgatgaccgc cgccttcgtc
  1485901 acgccatagg cgaagcggtt cggcacgccc tttatgctgg aagccacgga agccatgttg
  1485961 atgatcgaac cgtccttgcg tgcgatcatg ccgggcagga ccgcgcggat ggtacgaatc
  1486021 atcgacttga cgtttaggtc gaaggcgaag tcgagatcct cgtccttcat cgtgagtacc
  1486081 gagccagcat ggacgaagcc ggcgcagttg aaaagcacgt cgacggcacc ggtctcggtg
  1486141 atcagcgcct cgaccgcggc ggtgtcgagg acatccagcc gatgggtgct gatacccgcc
  1486201 tcgcctccga agctgccaag ggcgtcggtg ttgatatccg tcgcgtgaac cttggcaccg
  1486261 gctctggcga aggcgagtgc ggttgcgcgc cctatcccct gcgccgcagc tgtgacgagg
  1486321 acgacctttc cggcaaggtt cgctgtcatt ggatggttcc ttcagatttg cgttcgacga
  1486381 tcagaatgtg atcggcggcg agaacgacct cgccgcgttg attgatgacc tcgcaccgct
  1486441 cgacgacacg gccggccgcc ggccgcttcg gatcatcttc cttggcggcg atggtgaccc
  1486501 gtgtgcggat cgtatcgccg atgtggacgg ggcggacgaa tcgcagacgg tcataaccgt
  1486561 aggagaaagc gacgggattg atcaaggagg cggtgagccc cacgccgata gagaagatca
  1486621 tggtaccatg ggcaatgcgc tgcccgccgg gcagcgtctt ggcgaactcc gaatccatat
  1486681 gatgcgggaa gaagtcgccc gtatgcccgg catggacgac aaagtccgtt tccgtgatcg
  1486741 tacgcccgct cgtcagccgc acatgcccct gtatataatc ctcgaaatag atcgtctgct
  1486801 cgctcatttt cacttttccg ttgaaagcgc cgggatcggc gttgccggtc gggcgctcga
  1486861 ctgataggcg gcctcgacca gggccatcgt tcgccatgcg tcctcgaccg accctatgag
  1486921 ttcatcatca tcgcccgacg catggcgctg tatgttggcc atccggttgg caaaggcatc
  1486981 cggaaaccac gaaccttcaa gcggcactgg gacccattcg ctgcaatccg agggccgaat
  1487041 ccacagctcg tccggctcgc cccgcggata atcgagattg acgccgagct tgacataggc
  1487101 ggcacccctt gtccctgaga tccgaaactc gcaggcctga aatttccgcc cgtaaccgtg
  1487161 atcgtgattg accgaaagta cgcagcgcac cctctcgcca taatcgagga tcgcggccgt
  1487221 gcgggtctgc gccacatcgt ggttcggatg gccgatggac ttggcgtgaa cgccctgcgg
  1487281 atcacccagg aggtcgcgga cgaggtccag gtaatggatg gaatgcatcg caatctcgat
  1487341 gcgcggcagt cccttcagaa acggccagag accccaaggc gttgccagtg ccaaccaggc
  1487401 gtcgaaatcg accacctctc cgagatagcc tctggcgatg gcgtccttga gtgcaatcat
  1487461 catcggtgcg aagcggagct gaaagttcac tgccgcctta atctgccgcg cgcggcagat
  1487521 ttcaaggata tccgttgccg ctgcaagatt gccgcccatc ggcttctgaa tcagcgcgaa
  1487581 ggagccctcg ggcagtttcg agagaatggg gacgtgtgca gccggcggcg tcgcaagatc
  1487641 gaacaccgcg ttttccgccg ccaccgcttc ctcttcggtc gcaaatgccc ggatgtccca
  1487701 ctgctgggca agcgccgccg ccttttcccc gtccgggtcg aatatgccgg ccaccgggaa
  1487761 gccagccttc ctgtaggccg gaagatgcgc gtcgccgacg atgctgcctg caccgaagat
  1487821 cacgatggga cgcgggttcg ccggcttcgg ccaccattgc cggagagagg agggaatgaa
  1487881 ggcttcagtc atgatggaag acttcctcca tcatcgccca ccactcgccc tccttgcggg
  1487941 taacaagcgg tttctggcag ggcatgcaca ccgaccacca ttcctgattt ttcggatgcg
  1488001 ccgccatctt tgccatgtcg gcatcgaagt cctgaccgac atactcccaa tagccgaaga
  1488061 gaaggttttc cggctccttg aggaagatcg agtagttggt gatgttgcat tcgctgatca
  1488121 gcgcgaggat atccggccag acggccgcat gcagcctctt gtattccgcc agtttcgccg
  1488181 actcaagccc gatcaccatt cccattctct gcatgaccgt tcccttctac cggcgaaact
  1488241 cgcgggtgaa ctcggcgacc gagcgcgctt tgaccgcttc ccaatcccac gcaattccga
  1488301 tgcccggatc ggaaggcgcg attgccctgc cctcgcggat ctccattccc ttctgcgtca
  1488361 gatcgtcgag ctgcggaata tattcgacat attttccgtt gggcacggcg cagacgaggc
  1488421 tcacatgcag ttccatcagg aaatgcgggc agacgggaat gtcgaaggcc tccgccgcat
  1488481 gggccacttt cagccagggc gtgatgccgc cgatccgcgc cacatccacc tgcacgatcg
  1488541 agcaggcccc cttctgcatg tattcacgga aatggcggat cgaatagatg gattcgccaa
  1488601 cggcgatcgg cgtcgatgtc gaccgcgtca ggcgaatatg accatcgaga tcatcggccg
  1488661 gcagcggctc ctcgatccag gcgagatcga gctcccgcag ccgcgcggca cggcggatcg
  1488721 cctcgtcgac ggtgaagccc tgattgcaat cggtcatgat ctcgaaaccg tcgccaagtg
  1488781 ccgcgcgcat ggcggcgagc cggtcgtagt cctctgcccc gctcggcttg ccgatcttga
  1488841 ccttcgatcc cgagaagccc ttggccttcg cctgcaatgc atcctcgacg agagcctgtt
  1488901 tttcgatgtg cagccagccg ccttcggtgg tgtaaagcgg gcagctctcc ttcgcgccgc
  1488961 cggccagttt ccagagcggc agtttctgct ttctcgcccg caaatcccaa agggccgtgt
  1489021 cgacggcggc aagcgccagc gccgtaatgg cgccgatggt cgtcgcatgc gtcgcaaact
  1489081 ccatcttgtg ccaaagcgcc tcgatgcaat ccgcatcctc cccgatcagc atcggtacga
  1489141 gatgatcgga taggagccgc atgacggacg acccgccggt gccgatcgta tagctgtagc
  1489201 cggtgcccgc cgcgccgtcg gaatcggtga tcgtgacgat cggcgtttcc tggcttacga
  1489261 agctctggat cgcatcggtg cgtttgacct tcggcggaag atccaccatc cgcagttcta
  1489321 ttctctcaat cctcgccatg tcagcctgcc aaagcctttc ccgtttcgcc gtcgaagaga
  1489381 tgcgcccggg agagatcgag gctcatgcgc accttctccc ccgagcgcaa cggccgcggg
  1489441 ttcagcatgc gcgagaccca atcccgcccg ttgaattgcg tgaagacgag cgtttcgttc
  1489501 cccaagggtt cggtgatcgt gaccggaagc tcgagctcgt ggaccgcatc cgcatcgccc
  1489561 gcatggaggc catgcccgga aggatagatg tcgtcgggcc gaaggccgaa ggtcactttc
  1489621 tgtccttcgc gcagcgaaga gcggaagcgc ggcggaaccg gcaggctcgc tccagtcgta
  1489681 aaggcgagct ttccgtccgt cagcaccgcc tcctccatgt tcatcggagg cgaaccgatg
  1489741 aagccggcga caaacttggt ggccgggcgg cggaagacat cctccggcgt gcccacctgt
  1489801 tcgatatgcc cgtcgcgcat gatgacgatc cggtcggaaa gcgtcatcgc ctcgacctga
  1489861 tcatgggtga catagatcat cgtcgcctgc atgcgggcgt gcagcttctt tatctccgtt
  1489921 cgaacctggg tcctgagctt ggcatcgagg ttcgacagcg gctcgtcgaa gaggaagacg
  1489981 tccggctggc gcacgatcgc ccgccccatc gcaacgcgct ggcgctggcc gcccgacagt
  1490041 tgcgaaggcc ggcgttcgag gaggtgaccg aggtcgagta tggctgccgc ttcgtcgaca
  1490101 cgggtcttga tctcgtcggc ggaacgcccg gcgatcttca gagaaaaccc catgttctcg
  1490161 gcgacggtca tatgcgggta gagcgcatag gattggaaga ccatcgagat gttgcgtgcc
  1490221 cgtggaggca gatcgttgac cttgcgcccg ccgatctcga tcgcgccgcc gctgacctcc
  1490281 tcgagccccg cgatcatgcg cagcgtcgtc gacttgccgc agcccgaagg tccgaccagc
  1490341 gcgatgaact cgcggtcctt cacctcgaga tcgatgccgt gcacgacctc cagcgcgccg
  1490401 tagcgcttga cgagtttcct gagggtaacg ggcgccatgg acgattatcc tttcaccgcg
  1490461 ccgaaggtca ggcccgagac gaggtgcttc tgaatgataa aggtgagggt caacgcggga
  1490521 acgatcatca caaccgcaag cgcgcacatg ccgcgccagt cgatggtgaa ttcggcagta
  1490581 tagtcgagga gccccaccgg cagggtcttg gagttgacgg agcgtgtgat ctgcgaagcg
  1490641 agggcatatt cgttccagga cgtcaggaag gcgaagatgc cggctgaagc aatgccgggg
  1490701 ccggccagcg gaaactccac ctgccagaag gcctgccagg gagtgcagcc gtcgatctgt
  1490761 gcggcctccg cgagatcctt cggcacctga cggaaaaagc cgtcgatcag ccagatcgtg
  1490821 aagggaacgt tcagcgcgac ataggtgagg atcagcgaga aatgcgtgtc gatgatgccg
  1490881 gtgcgggcat agagcatgaa gagcggcagg gacagcgcaa tgcccggcac tgcgcgcgtc
  1490941 agcatgaagc cgaggaagat cgccgatttc gccttgaaac ggtaccgtgc gaaagcatag
  1491001 ccgccggaaa ggccgatcgc gagtgcgatg acggtggagg tgaccgagac gatgagcgaa
  1491061 ttgcggaaat aatcccagac cgggacgcct ccctggccgg cacccgaaaa cattgcccgg
  1491121 taggcgtcga gagagagcgt ctcgggaatc cagaccggcg gcttcgccat gatctctaca
  1491181 gtcggccgca acgatgaaag cacgatccag aggcccggca ggcagatcac ggccatcgcg
  1491241 aggaaaagcc ccacgaagtg cgccgccttc aggagtcgcc ggcgcaggcg atgggatgcg
  1491301 ttcgtatcca ttaccactcg gctccgatct gctggcgcgc cgcggcgagc ttgcggaaga
  1491361 aatacaccgt gaagacgatc gagagcagga tggccacata ggccatggcg ttggccaatc
  1491421 ccatgcgggc gtcgccatag gcggtacggc cgacgagggt ccagagcagc tctgtgcgct
  1491481 tggccggacc gccatccgtc atgatcttga cgatatcgta ggcgcgcgcg acatcgagcg
  1491541 aacggatcgt catcgcgatg aaggcgaagg gcatcagata gggccaggtg acgtagcgga
  1491601 aggtttgcca gggcgtgcag ccatcgacat gcgccgcttc gaccggatcc ttcggcatgg
  1491661 cgagaaggcc ggcgaggatg aggatcgcga agaccgccgt cgacgaccag acctcggcaa
  1491721 cgatgataga gaagagcgcg agattgccgt cgatcagcca ggggatagcg cggtcgctca
  1491781 ggcctagcga ctgcagcgca ttgttgacga agccgatatt gtcgttgaac agaaatttga
  1491841 actggaagcc cacgagtacc ggcgaaaaca tcatcggaaa catcatcgcc gttcgcagaa
  1491901 tacgctggcc gcgcgtcgcc ttgttgacga gcagcgccaa accgaggcca agaagcattt
  1491961 cggcgttgag agcgatcgta agcaggagca ccgtccggcc gaatgcgacc cagaactcgg
  1492021 cattggtgag cacgttcacg tagttcctga agccgatgaa tacccaaagc gtgtcgggct
  1492081 ttgtcagccg gaacggcgta aagctggagt agagcgaaaa catcagcggc agcacgatga
  1492141 agactgccag aacgatgaag gccggaagca gcagaagcgt aggtgctgac aatttcgaga
  1492201 gcttcatcgg agatccacta aaaaggtgaa gatgcagaac ggcgccggct cggccggcgc
  1492261 cgttctcgca atttgtgcta gagcttgccg gcgtcttcga ggatgccggt cgccttttcg
  1492321 gcggcagcat cgagcgcttc cttcgacgtc ttgtcgccga ggatggccgc ctgaagctcc
  1492381 ggatagacgg cattggatat ctcgatccac tcggccgtct gcggaaccgg gaaggcgtgc
  1492441 tttgctgcct cctggaaggc ctgcagcacc tcggtcttgt aggcgtcgcc ctcggcggcc
  1492501 ttgatgttgt gatcccatac ggcgctgcgg gtcggaagag ggccggctgc ggattcgagc
  1492561 atctggctgt cttcgttggt cagccaccag acgagcgagg cggctgcctc cttgctcccg
  1492621 caggactccg ttaccgaaaa gccgtgatgc ccggaccagc cggtgcgctt gccggacgac
  1492681 ccggccggct gaaccttcac cccgacattg ccggcaacct tcgaggattt cggatcgttg
  1492741 aagaaggacg cccagccagg ccagtcgaga ttgaccgcga tcgagcccga agcgaagccc
  1492801 tggccgagat cgtcccagag atagttggtg gtgcccggcg gaaccgcttt gcttttgtag
  1492861 agcttgacga accaatcgag ggcgcgcacg cccgcttccg aattgaacgc cggtcggccg
  1492921 tccttgtcga gatattctcc accctcggcg accagcatct cgtagaagcg gccgttgatc
  1492981 gcttcctcct tgccggcgaa ctgcgtgccg tagaagttcg gcggcgcggc gaagaattcc
  1493041 gcctgatcgc tcacctgagc ccaggtgtcg ggcggtgcga gatcatagcc gtacttggcc
  1493101 ttgaactcgg ccttcttcgc ctcgtcctga taaaggctct tctggtaata gagtgccgag
  1493161 acgtcgaatt gcgcccgcgg cagcatgaca agcttgccct cgagcgtcga ggcatcgatc
  1493221 acggccggca cgaacctggc gacctcctcg gacgggacga ggccgaaaag atcggcgtag
  1493281 atatccggat attgcggtgc gaatgaggaa tgattcgaac cgatgcacca ggtgatgccg
  1493341 ccggtggcga tgtcggattt gatctccttg tcgagttcga agtggttctt cttcgacaga
  1493401 atgttgacct tggcgccggt cgccttctcc cattcgccga tgcgctcgta gagcttttca
  1493461 tattgctggc cgccaatcag cttggcgtcg atggtaacac cctcgaactt gcccggcagg
  1493521 tcagcggcac ttgccgcccc catagcgcag acaagcatga ttacaccggc cgatacgccg
  1493581 gaaagcagcc tgttcattgc atctcctccg ctgaacacac ccttctcctg gggcgtgagt
  1493641 cctcatccgt gagaaactaa tttatataca aacaacaaat ttattcccgg tcaagggcgg
  1493701 ttccctttcg tctcccgttt tttatgcgta tatggttctt tatattcatt ggagatgacg
  1493761 cggaatggac agtgaagagt ccgacaagta tcgcgcgccg gcgctggata aggggctcga
  1493821 cattctggag ctgctcgcca gcgtggacgg cggcctcacc caggcggaaa tctcaaagag
  1493881 gctgaaccgc agtccgaacg agttctaccg catgctcgac aggctcgtgc gccgaggcta
  1493941 tgtgacgcgg atcgatggcg acctttattc gctgacgctg aagctcttcg gcctggcgca
  1494001 gctgcatgca ccggtgcgca ggctcgtttc cttcgccacg ccgctgatgc gcgagctggc
  1494061 gcagcgctca aagcaggcca accagcttgc ggtcttcgac cgcggttcgg cggtcgtgat
  1494121 cgcccagcag gaagcccctg actattgggg catttcgatc cgcgtcggct cgcatatcag
  1494181 cttgttcgat accggatcgg gccacgttct gctggcgttc cgttcgccgg aagaacggga
  1494241 gatgatgatc tccgaacatg ttcgcagcag agacgagatc aatctcactc cggaattcta
  1494301 cgcccgtctc gaccagatcc gcgagcgcgg ctatgagatg atggcaagcg cgcagaccgc
  1494361 cggcgtctac aacctgtctg ctccgatcct cagctcggac gggcgcagcc tcgcggcgct
  1494421 cacctgcccc tatatttccc tggtgaacaa tccttcggcg cccgacatta ccgagacaat
  1494481 atcgctcttg ctcaagaccg cgtcgcagct ttcggcgctg gcgggtgctg atgttgcaca
  1494541 aggctgaagc gtattctcat ctgaatgaac ctatgtggaa ctctgatcgc ctgaagagga
  1494601 ggagcagcct tgatcatcga cacgcacctg catctgatcg acaaatccgc gttgagctat
  1494661 ccctggcttg gcggcgtccc cgcactcgat cgcgattttc tctattcggc ctatgcggca
  1494721 gaagcaaagc gtgtcggcat tgccgcttcg ctgcacatgg aagtcgacgt cgaggcgggt
  1494781 cagatcgaac gcgaaacgag cgagattgcg cgtctgtcgc gtgagccggg aagccttctg
  1494841 aggggcgcga tcgccgcctg ccggccagaa gacgacggct ttgccgccta tctcgagcgc
  1494901 caggaagcga acgccttcgt ccggggattc aggcgggtgc tgcacgtcgt tgccgacgat
  1494961 ctttcggaac agcctctttt ccgcgaaaac atcaggcgcc tttcagcgac gcgcttcacc
  1495021 ttcgatctgt gcgtgctgcc gcaccagatc ccgaaagcga cggctcttgc cgacctcgcg
  1495081 ccggaagtcc gtttcgttct cgatcattgc ggcgtcccgg acatcaaggg ccgggcggag
  1495141 cacccctggc gcgagcatat gaccgaaatc gcccgccggc cgaatgtgac tgcgaagatt
  1495201 tccggggtga tcgcctatgc cgaggaagat tggacgcttg cctcgatccg cccctatgtc
  1495261 gagcacacga tcgccgcttt cggctgggac cgtattgtct ggggcagtga ctggccggtc
  1495321 tgcacgcttg gcggcaacct gtcgacctgg gttgcggcga cccatgccct catcgaaggc
  1495381 tgcagcctcg atgagcggac gaagctgctt tcgggcaatg cacgccggat atggaatcta
  1495441 ggctgacggc attacagctc tggcgggtgc attcatcccc cgcatctctg tgcacgtcac
  1495501 aggattgagg gagagcaaac cgtgccgggt gccgccgtca tgatgcgccg cggtggcgtt
  1495561 ccagcgcctc gaaatgattg gtgatctcct cgccggtcgc gatccacacg tcgccctttt
  1495621 cctggacgtg gcgaaggaaa tcacgaagga gatgccagcg catcggacgg cctgacacct
  1495681 gcgggtgcag gacgagcgtc gtgacgccgc cccaggcatg ggtggcctcg aattcgtcga
  1495741 tccagagcga caggacggct tcgcggccga agagcggcct cgggctcgca cggctggaca
  1495801 tgccgaaatt ccaatcgtcg aatgcgaagt tgatgggaat ctccacgggg cccggcatgc
  1495861 cgtccgatgc ggcgtgccgg tacggcagga tgtcgtcgcg aaacgaactc gaatagcgga
  1495921 tgcccgatct ggcgagatag gcgatgagct cgggaaaatt ctcccccgag ggcgcgcgat
  1495981 agccgaccgg acgtttgccg aatacccgtt gcagcgcatc gaaaccgcga tcgatttcct
  1496041 cgaatgtctc gtccagccgg tcgcgatccg gcatcttgtg aagatagcca tggtgaccga
  1496101 tctcatgtcc ggccctcagg atcgtctcgc aagcttcggg gtgcgcaagc gcggtccagc
  1496161 cgggcgtgaa gaatgtggcc ttcaacccca gttcgtccat cagtccgacg atcctggcga
  1496221 tgccgacacg cgcgtcgtaa ccgccatggg acgtggtcac catgcggtcg atgttggagg
  1496281 ggctgttgcc gatccatgcc gtttcggcgt caacgtcgaa gccgatgaag acggcgcttc
  1496341 tcgcgccgtt aggccaggtc atcgccgggg tccgcggcgc cttattgagc gggcgcggcg
  1496401 tcaggtcgta ggtcatggca aggtcctcag caaaagacag gacgcctgtc gccgtcgccg
  1496461 gcgagcagtg cttccagagc acggcagtca ttcaggtttt cgatttcggc gagcatccgc
  1496521 cagagcctgt ccgcctgctc cggttcgatg ctcatcgcgg cgagcgcgtc gaacttggca
  1496581 tgaatggcgg ccggctgcat cggcctttcg gccgagccgg tcgcgcgtgg taccgtcttt
  1496641 gacacgcgcg taccatcctt gaacagaagc gtgacgatcg gctcgtccag cggctgcatt
  1496701 gtatcgtcca cctcaagaag catgccatcc atgacggctt gcacgcgggg atcggcgcgc
  1496761 cggtcggccg cataggatgc aagcccggcc gtgccgaaaa cgcaacgcgc ggcgagcgcg
  1496821 tatgggaggc tcatttgcgc ggctgccatg gcgccgctct ccctggcgcc gcacatgccc
  1496881 atcagcatgg cgctcaaacg caactcgatc ctgtcgatcg ccgccgcatc gcggcccgac
  1496941 tccgacaaaa gatcgtcaag cgcatccacc gcggagtggg caccgcggca ggaggcatag
  1497001 ggtttgagga ccgcgcgctt cactttccag ctctcgccga gcccctcgca caggttctgc
  1497061 ggctcgcagg catccttgtt gaacgctcgg aagaacccgc cccagacatc ttcgaagacc
  1497121 ctggaagggc ctgcaaggcc ctcccccgcc aaccgcgccg cgagcaagcc gccttcggcc
  1497181 gcccggcccg catggacctt cttggcctgc gatccatcat ggatgaaggc ccagaggccc
  1497241 gaggaaaaac ttgtggcgag cgtgatcgca tcgcgcgtgg cgagactgcc gaagccggaa
  1497301 agcctggcaa cggccgcagc agccgcaagc gcgccgcagg tgcccgtcga gtgccatcca
  1497361 agtccgttgt gactgtcgta tccacccgcc gcttcgagaa cacgccggcc cacctcgtaa
  1497421 cctgcgacga cgctggcgat cagttccctt cctgatacgg ggccgggaac ctcggagatc
  1497481 gcggcaagaa ccgcggggat gaccacggcg cccgaatggt cgcatccgcc ggaatcgtcg
  1497541 agctcgaggg catgggccgc gacaccgttg acgagcgccg catcccgggc ggaagtgcga
  1497601 ccgccggtcc cccagatcag cgcgccgccc ggcgtgccgg ccgtgcggcg ggcgatggcg
  1497661 gcttccgcgg aacatgcgcc ggccagtgcc gcgccgatcg tatccgcaac gtgtactttc
  1497721 gtcttctcca cgacatcgtc gggaagtgtc tcgaagctga tcttcgagac gaagtaggcc
  1497781 agcctgtcga ccggcgcgtg ggcctgaacg cgggacatgg aactgctcat tttcttgtca
  1497841 cggagggata gccgcggcgg tggccctggc agttctgccg gggccatggg acgaccgccc
  1497901 tactgcgccg gttcaccgtt gatgtaaatg ccatcgagca aggtgccttc gaggccgtat
  1497961 ttggcgaaga tcgccttgta ttcccctgat tgcatcagcg ccttcagcgc tgcggcatag
  1498021 gcatcgcgca gttccgcgtc ctttttggca aagcctatgc cctggtacac cgtcgtgaag
  1498081 ggctcgccga cgacggcata ggtgtccttt tcgaggtcca tgaggtaggg cagcgtttct
  1498141 gaaccctgga ccgcggcatc gagccggccc tgcttcaact gagcacgggc gtcggcggag
  1498201 ccttccgtgc cgacgacctt gatcgcgccc agccccttgg cttcgcaatt ggcagcgctc
  1498261 cacttcgccg tctcgtccgg gaaggaggtg cggcggctca tgccgacggt cttgccgcag
  1498321 aaatcggtga gcgtcttgaa ctcgtccttg cggccgaagg acgtatagaa ctgcgcgccg
  1498381 gacttcatgt aatcgacgaa atcgagcgtc tcgcggcgct tcggcaggtc gctcatgccg
  1498441 ctatgaatca ggtcgacgcg accggtcgtc agcgacgaga tcatctgctc gaagccgata
  1498501 ttcgtccatt cgacggtggt gccgagttct ttggcgagcg ccagaccgag atcgatgtcg
  1498561 acgcccttca gttcgtttgt ggccgggtcg acatattcca tcggcgggta gttcggctgg
  1498621 ttggcggcga cgaccttccc ggccgtcttg atccgctccg gcaagccggc tgcactggca
  1498681 gaggttgcgg cgaggcatgc gacggtgagc gctgcgatat gcttgttcat gtggttcccc
  1498741 atctttgtct ggttcgatgc gaaggcttcg tgcgaagccg catttctgtt cctcagctat
  1498801 gaacggcttt gatgaactcc tccgtccggg cacttttcgg ggtgctgaga acctccgatg
  1498861 ccaagcctgt ttcgaccacc ttgccggtct ccatgaaggt gacggtattt gccacgttgc
  1498921 gggcaaagcc gagttcatgg gtgacgacga tcatcgtcat tccggaggcg gcgagatccc
  1498981 tcatcacgtc gaggacttcc gacaccagtt ccggatcgag cgccgacgtc ggctcgtcga
  1499041 agagaatgag atccggccgc atgcccatgg cgcgggcgat cgcaacgcgc tgctgctggc
  1499101 cgccggaaag ttcggatgga tagtggtccg ccttgtccgc aagccccacc cgctccagca
  1499161 gcgccgaggc tctggagcgc gcttccttca ccggctcgcc gagcacgtgc accggaccct
  1499221 cgatgatgtt ttccagggcg gtcttgtgcg ggaaaaggtt gaagcgctga aagaccatgc
  1499281 cgatccgccg cctttggcgc gaaatctccg catcgctgat ctcgtggaga ttgttgccct
  1499341 cgcgccggta gccgatcaac tcgtcgttga cccagatccc tccgccgtcc atccgctcca
  1499401 gcaggttgat gcagcgcaaa agcgtgctct tccccgaacc ggagggaccg atgatgcagc
  1499461 tcacttctcc gcgggcgacc tccaggctca ccttgtcgag cgcgcggaaa gtgccgtagt
  1499521 tctttgtgac gtcgattgct ttgacgagaa tatcctggtt catgaccgac ctcacatgga
  1499581 cgagcgtatc gatttcgaac cgcggccgaa atagcgctcg atatagtgct ggccgaccga
  1499641 gagcacggaa acgacgagca ggtaccagaa gctcgccacc agcagcagtt cgagcacgcg
  1499701 ggtattggcg aaatagatga tctgggcgtt gtgcaggatc tcggaatact ggatgacgct
  1499761 cgcgagcgac gtcagcttca ccatgccgat cacctcgttg ccgaccggcg gcaccatcac
  1499821 gcgcatggcc tgcggcagga cgatacggcg cagcatcatc atctgggtca tgccgatcgt
  1499881 gcgcgcggcc tcgtactggc cgctgtcgac tgacagaagt ccgctgcgca ccacctccga
  1499941 cgtataggcg ccctgcgaaa ggccgagacc gagaacggcg gccacgaagg gcgtcatgac
  1500001 gtcgaccgtc cggaattcaa acagtccggg aatgccgagc gtcggaaaga tcagcgcgag
  1500061 gttgaaccac agcatcagtt gcagcagcgc cggcgccccc cgaaagaccc aaacatagcc
  1500121 gatggcgatc gacgacagca ccggattgcc cgaaatccgc atgatggcga tgacgacgcc
  1500181 gagaacgatg ccgactccca tggcggcgat ggtcatcagc aaggtgttgt agaggcctgc
  1500241 gaggatcgcc ggggcaaaga ggaaatcgcg gacgtagctc cattcgatct ggccgacgct
  1500301 gaatgcccgc acgaggccgg caagcagcaa gagcacgatg ccagccgcaa ccattctgcc
  1500361 gatgtgacgc ttgggcacca gtttaaggtg ggcgatctcg tatttggcgt cggtggggga
  1500421 agacgtcaga tttgccacat tcatcgacgt cgctcctcct ctacgtcgct cttcggaccc
  1500481 gcaaaggccg ccccgccgga tggggcggca gcaaaggccc ggcattcggc aagtgccgtt
  1500541 tcgaaacggg cgatctgctc gcgaaccctt tccggcgcgg ttgcgccgta tccggtgcgg
  1500601 ctcgcaagcg ccttgtcgag tgtgagcgct gcgagcatcc cggcgtgaag acgcggatcg
  1500661 atcttcgcca ggtcgtcggg ggtcagcccg gcaagatcat gaccgcgctc ttcgcagtag
  1500721 cggaccacgg ccccggtaat ctcgtgcgct tccgcaaagg gcacgtcccg tccgaccagc
  1500781 cagtcggcga cttcggtcgc cagggtgaag cccttcggcg cttcctcccg cagtttctcc
  1500841 acgtcgaatt ccagcgtccc caccatgccg gcaaaggccg gcaggaccag gtcgagaatg
  1500901 tcgatcgtct cgaacaggct gcgcttgtct tcggcaaggt cgcgattata ggcgagcggc
  1500961 atcgccttca tggtcgccag gaacccggca atgttgccga tcagcgtgcc ggacatgccg
  1501021 cgcgtcagtt cggcgacgtc gggattcttc ttctgcggca tgatcgagga acctgtggaa
  1501081 taggcatcat cgagccgcac ccagctgaac tgtttggagc tccaaaggca gatttcctcc
  1501141 gcaagccggg agagatccac cgccaccagc gagcagatga agagaaactc cgcgacatgg
  1501201 tcgcgcgctg cgacagcatc gatggagttc tcgcacgcgg ccgaatagcc gagatcgacg
  1501261 gcggaaaggt cgggacggcg ggcaatgccc gatcccgcta gcgcggccgc gccaagcggc
  1501321 gaccgatcga atcggcggtc ccaatccgcg aaacgctgaa ggtcgcgcag cagcgactgc
  1501381 gcatgcgcca tgaggtggtg cccgagcacg accggctggg ccggctggag atgagtaaag
  1501441 ccgggcatta ccgtttccgt atgccgggat gcctgctccg tcagcgcttc ctcgacggcg
  1501501 ataatgcctc gggaaagctc ccgcgccata cgccgtagat aaaggcgcgt attgttcgca
  1501561 gtctgatcgt tgcgggaacg tccggcgcga agcttgccgc caagggcgcc gaggcgcgcc
  1501621 atcagcaggc gttcgagaaa ggtatgcaga tcctcgtcag cggcaatcgg cttctcatgg
  1501681 ccggcaccga catcggtttc gatcgcttcc agggctgctc gtatcgcgga gaattcgccc
  1501741 tcgtcaagga cgccggcgcg cttcaattcc gaagcatgag cgcgcgaccc cgcaatatcc
  1501801 tctctgtaaa ggcgaaagta agagctcggc gcgcgtgaca gatttgcaag cgcttcggac
  1501861 ggtccggact tgaatcgtcc accccagagc tgagtgggtt cagccatttt cgttcccttt
  1501921 atttgttcaa tcttttcgag aggctcccat gggccgcatt cgcccgcaag cgaagttatt
  1501981 tcaccagcct atgacaaaaa cgactagcct tgaccggagc acttatttag ggtttgcgca
  1502041 gaaaaccggg gcggatcgga gagaattgcc tcgcaagata gagcgggatg cgggcagaaa
  1502101 accgcgcaca cctttcctca tccccgctct cgcatcggct tgacctatcg gagggatttt
  1502161 catggcctcg ggacggcggc gcctgccttc gaccacagca cttcaggtcc tgcttgcggt
  1502221 ggccgaaagg ggctcgacga gcgctgccgc cgaaagcacg tcgctctcgc aaagcgccgt
  1502281 cagcaagcaa ttgctggcgc ttgaagcgct gatcggcagt tccgccttcg cccggacatc
  1502341 gcgcggcatg atcccgaccg aggtcggctc gatctatatc gaacaggcgc gcattgcctt
  1502401 gaaggcaatt gaggacgccg cgctgcgggt cgcgcgcctg aagccggggc cgcgcgttct
  1502461 tcgcctgcag gtgccgccca tcttcggaga ccgatggttg ctgccgcgct tccttcgttt
  1502521 caccgagcaa caccccgaga tcgaggtgca gttcaccacc ttcgtgtctc cgacccagtc
  1502581 cgagacgccc gatgcgatat tccgattcct gaccgaaccc ttgccgggcg aggagaccag
  1502641 ctacctcttc gggcgcgagg ttctggtcgt cagcgcccct tcctactggg agaagaacgg
  1502701 aactccggaa accatcgagg agctggcgga tggcgtcatg ctcgagcatc cgcaaacgcc
  1502761 gttgcactgg cactatttcg ccgatagcca cggaaagcgc gaactccccg tgcgccacac
  1502821 gacgcgcttc ggctattaca ccatggtgat ccgcgcggcg cttgccggac agggaatggc
  1502881 cttgatcccg cgcggcctta tcctcgacga ccttgccgcc ggaaagctcg tcaatccgaa
  1502941 cggcttcgga tatcgaagcg aatacggcta ctggttcgca aagccgcggg acattgcacc
  1503001 aagtgcgtcc atgcgcattt tcgaaacatg gctgatggcg gaagcggaag gcatgggcga
  1503061 ttgacggatc gtgatctaag ggaagaagaa agactgcggc cctgcgatcc ggaattctag
  1503121 cgcatcgcga tacgcgccga caaacgagag ctccaacgcc atcatccatc tcacagcggc
  1503181 cgtcataaac tcaaagatga atctcaacag gcctagcggg ccggctcagt tcgcaagctg
  1503241 cacaagcgcc tcgccgtcga gccggaagaa gagcttgtcc gttttgcatg cgccgccgag
  1503301 ctcttcatag aaggcgagaa gcctggcatt ctccgcgtct gcggtccaat cgatgcgcga
  1503361 gagtccccgt tgcgtcgcca cgctggcaag cttctgcatc agggcccggc cgaggcctcg
  1503421 gccccgctgg gatccggcga catagagttc cttgagaaat agccccggct tcagccctgg
  1503481 cccgggatag atccccgaaa accccgcaaa accgaggatg cgatgctgtt cctcggcaac
  1503541 caggatttcg gcgccccggg gcatggcttt aagcccggcg atgatctcgg agcgaggcgg
  1503601 acaagccacc cggtaatgcg cctgcatttc ctccatcagg atcgcgagcg ccggcagggc
  1503661 cggatcatct ggctgcagca ggcggattgg tagcatcaca gattccgttt tatcggctca
  1503721 actcgagcgc gccgccaccc aattgtgcca atcctcctcg ctgccgttga agacgttgag
  1503781 atcgatccgc ccctcgacgc cgtgggacag acccgaaccc gaatattgcc agaacaccca
  1503841 tttgcgtccg ggataaacct tggacggatg ggccgcgacc gagcgcagcc agaagggatg
  1503901 attgggaaac gcgccctgca gattgtcgcg gtagaagtca ggcgcggtgt agatgatcgg
  1503961 gcgctggccg taatgccgct ccagcttgtc catgaagacc tgcatctttt cgagcacccg
  1504021 ctcgcgcgag gggcgccgtt tgcagctcga ctcaccgttc cattcgacat cgatcacggg
  1504081 gggaagcgcg gtcggatccc gcggcacgtt gcgaatgaac cagtcagcct gctcgccggc
  1504141 cgtgcggcac cagtagaaga agtgataggc gccgcgtttc agtccggctt cgttcgcccg
  1504201 gcgccagttc ttcttgaaca tgggatcgag atgatcgccg ccatcggtcg ccttgatata
  1504261 ggcgaagttg gcgccctggc tgcgcagctt cgcccagttt atgtctccct gccaacgcga
  1504321 aacgtcgacg ccatgaacgg ccattttgcg cggtgatctc ttgccgaagt tgatcggatg
  1504381 ggcatcacgg aagctgtggc tgtaaacgcg tgtgcggccg ccccgaggcc ccgcgggatt
  1504441 ttccggagcg agcatcgcaa gcggacgctc ggcgggcacg ggcatgccga cggtcctctg
  1504501 cgcggacgta aaagcctggg gctccggcac cggccccgcc caggcgagcg cctccggcgc
  1504561 gcttttcgcg gcaacggcgc tgacttccgc tgacggaacc ggacttgccg gacgcacgga
  1504621 gctcgtcgtc tcccgcgagg gacgatcacc cccgaagccg cagcccgaca gtaccagacc
  1504681 aaatatgacg atcgctgaaa caactgaaaa atgacgcatg aggacccgca cgcaatacaa
  1504741 aaagccgacg gcgcatgtgc cgccaggacc cactgacgag acttgctaac gggaaattac
  1504801 caaaaaagat tgaatccatt ctttacgagg gccgcggcgg cagtggaaca agacggcgcg
  1504861 gcataaccct tctccccgtc aaaacgggga gaagtggcgg catccgtatg atggcccggc
  1504921 cagcggcttg tttcagcgaa aactctcgca gaacagccga ttgagttctt cggccacgag
  1504981 gcttggcctc tcgccgcgct tgagcccttc gttcaggcga tccgaacccg cctgctggaa
  1505041 tgccatatag ccgtcatggc gcggccggag ccaggcagcc tcgagcgtcg cccgggtcgc
  1505101 gcggtagaaa tcatgcgtcg ccgcattgac cgtctcgtcc tgccaggcgg cgccatggcc
  1505161 gggctggccg ccgcaggcgg cgtagatacc ccgctgcacg tcgccgctcg ccacccaata
  1505221 ggcaaaatcg atcgcctgct ccggcgcctt cgaaaaggcg gataccgcaa tgcccgtccc
  1505281 gccgagagcc gagccgaccg gtcctgccgc gccgatttca ggaatatcgc cgaagcggat
  1505341 gagcgccggc cgaaagcccg ccatcgagta gctgacatag ccgtagatga gcggcgcgca
  1505401 ggcaaaggcg gacccctttt ccgccatcgc ctcgaaggct gcgatcggat ccatgtcgaa
  1505461 gcagtccggg tcgaccaggg ctgcgatctc cttcagcagc tcgattgcag cggcacccgt
  1505521 ttcggcatcg acgagctcgc cctgcccgtt gctgcggcag ggccgcccca gattgccgca
  1505581 gagggtgaag aagctcatca gcgaatgggg cgggcgaagc ggcagaacga cgccgcctga
  1505641 acgcgccagg tccagcacct cccgccaggt ccggaggcgc tcggtccgat ccggccgcca
  1505701 ggcctgcacc tgggtcgcgg catcgatcgg aaaggcccat tggcgggcgt tccattcgta
  1505761 gctgcgatag gaggggccga cacttgccgc cgagagagcc tgccgatcgg cctcacgccc
  1505821 gggcacgtcc agcggaagca ggcagttttc gctggtgatc tggccgacat gcggatgatc
  1505881 tatgacgatc aggtcgtaat cccttgcaag aacttccacc ggaaacgtct cgaagtcctg
  1505941 aagcgaccgc ttctcccatt ggatctcgac gcccgacgtc tcctgccagg cccgcgagca
  1506001 ggccaccatc gggtcgtagc cgcgcgggtg gttccaggtc attcccttga ggacgaggtt
  1506061 cacaggccga actcctctct gatcgatgcg ccgtgctcgc cgatccgtgg cgccgcgcgc
  1506121 tcgacgctcg gccggcggcc attgatccgc agcggcgaac gcgtggtcgt aatcgacacg
  1506181 tcgtcttcgc gcatcaccgt ctgcagcatg tcgaggacct gaaaaccctc gctatccaag
  1506241 agttcgttcc aatcgagcac gcgcgcgcac catatgtcgg ccggctccag caccgcgagc
  1506301 cattcgtcca aggtgcgttc cgcgattcgc gcggcaatca gcgccttgat ggggtcgcgc
  1506361 tcggtgaacc acgcggaggg atcgtcgcga tagggcgcga gcgcgtcgat ctgcaacagg
  1506421 tctgccagct tcgggatcgg cgtcatcgcg atcgcgagaa agccgtcgct tgccgcgtaa
  1506481 accccgtagg gcgcggaaag ataagcatgc gcgcttcgga acgccgaccg cttcggcagc
  1506541 cggcggccgt cattgagatg agtcgtgagg acctcgaact ggaaatcgac cagcgcctcg
  1506601 aggaggctcg tttccaccag gcttccttta cccgaaatgc cccgccgcac caatgccgcg
  1506661 agaatccctt gagcagcggc ggcgccggcc agcatatcgc cgatggcgag cccgaaggga
  1506721 accggcccct gcccttcgtc gccgttcagc cacatgacgc ccgagcgcgc ctgcgccagc
  1506781 aggtcctggc cgggacgctt cagccagggg ccttcttcgc catagccgct gatcgaggca
  1506841 taaaccatgc gcggattgat cgccctgacc gcttcgtaat ccagccccag cctttcgatg
  1506901 acgcccggcc ggaaattctg gatcatcacg tccgccttgg cgagaagccg cttcagcgcc
  1506961 gcgaggtcgt cttcgttctt gagatcgatc gcgaggcttt ccttggcgcg attgatggcg
  1507021 tggaagatgg tggaatcgcc gccgatctcc gtgtcgctca aataaagccg ccgggaaaga
  1507081 tcgccgccgt ccggccgctc gatcttgatg acgcgcgcgc cgagatccat cagccgcagc
  1507141 gaacagtaag ggccggaaag aaactggctc atgtcgacca cgacaaggcc ggcaagcggc
  1507201 aattcggact ctgttgtcat gcgtagctac tctttccctg cggcaatctc gaacaagatg
  1507261 tcattcttat ttgaatatat agttcacata tagattattt tgacaagccg cgagtggagt
  1507321 aaaagagcct cgccagcccg aggacttggg ccggcaggat tcctgtgaca gcaggaatga
  1507381 ggggaagctc aggcgcatcg ccctacatct aaaatgctgg cgatagccgt atcggacatg
  1507441 tagaagacgt gctgacgcac ggcactggcg tcgggaatgg cggatcggca acgggaaatg
  1507501 tgaatgaaac ctcacgccgg cgagggctca cgagcgacgg atttcggtag cggcgctgcg
  1507561 cctcaggggc gccgaacgac ctttgccgtc cagatcaccg agtggaagcg ggagcctttc
  1507621 gaacgatatt tccccgacag gcacttccac ttccttccga tgaatctcgg cgaacacgag
  1507681 ttcgagcgcg tctggaagcc gcgaattctc gccgagagca gcgccgagat actcgcctgg
  1507741 gggccggagc taccaggccc gctggatgcg ctggccaaag cgcggaacat tcctgttact
  1507801 ttcattgagg acggcttcct tcgttcggcc aggccgagcg ccagccgcac gcctcccctc
  1507861 tctctggccc tcgacagcaa ggcgatctat ttcgactgcc ggcatccctc gcagctcgag
  1507921 gagctgttgg gaacctacga tttcgaggcg gatgcggaat tgatgacgcg cgcgcgcgcc
  1507981 ggcatcgcgc ttctcaccga aagcggcatc agcaaatata atggcggccg gcagcggacg
  1508041 gccgaagagg tttacggcga gaagacgcgc aagcgtgttc tggttgtcgg ccaggtggag
  1508101 gacgatgctt ccgtccgcta cggctgcctc agccggatga ccaacaacga cctggtgcgg
  1508161 ctcgcggcct cagagcagcc ggacgcccag atcctctaca agccgcatcc ggacgtgctg
  1508221 agccgcgtgc ggccggcaag gtccgatccc gcggaagtcg cgcacctttg caccctggtc
  1508281 accgagagcc tgccgcttgc ggaggcgctg cgcaccgtcg atcacgtcta tacgatcacc
  1508341 tcgctcgcgg gtttcgaggc gcttatccgc ggcatcgagg tcagcaccgc cggctgtccc
  1508401 ttctattccg gatgggggct gacggacgac cgccagccta acccgcgccg cgggcggcgc
  1508461 ttgagcatcg aggcgctttt cgcgggcgcc tatctgcttt atccttgcta tttcgacccc
  1508521 gagaccggag aacgatcatc attcgaagca accgtcgcga cactcagaag tcagctggaa
  1508581 gagccgcagg gccttgcccg gccgcggccg gcctggcgcg cctgggggcc ctatggcctc
  1508641 ctcggctggc gccacctgct gccgcccttc gtcacgcccg tgatccgcaa gataggcagt
  1508701 gaccgcgatg tcgaagactt cagggccgat ccgatccgct tcttccgcac cctctccgac
  1508761 cggaagttcc gcgtcatcgg ccgtattctc tatccgttcg ggtgattgag atggagtacg
  1508821 tcgccaccca tctccgtgtc gtcgccgcgc tgctggtacg ggaaatgtcg acacgcttcg
  1508881 gctcgaaacc cggcggctat gtctgggcgc tgctcgatcc cgccgcccac atcctgctga
  1508941 tgacctcgat cttccaggcg atcgcacata cgccagcgct cggcacaagc ttcgcgctgt
  1509001 tcttcgccac aggctatatc gccttccagt tctaccaggc gatgaacggc tatctgaacg
  1509061 ccgcggtcaa ggccaacaag gcgctgctca gctatccgaa tgtcgcgcct atcgacacga
  1509121 tcgtcgcgcg cttcgtcctg cagatgggca cgacatcgct ggtcgccttc atcgtgctcg
  1509181 gcacgatcgt cgccaccatg cgggtcgata ccgaccttca ctggccctcg atcctggagg
  1509241 ccatcgcgct cgcctgcctt ttcggcctcg gcgtggcctt gatcaactgc gtgctcttcc
  1509301 tcaaatatcc gctctacgag caggtcttcg gcatagtcaa ccggccgctc tttctcatct
  1509361 cgggcgtctt cttcctgccc gactcgattc cggcacccta tcgcgagctg gtgctcatca
  1509421 atccgctcgt tcatatcatc atgggcttcc gcaagggctt ctacccggag tatcgggcaa
  1509481 tcgggctcga tatggactac ctctacggaa tcgcatttct gacattgttt gccgggatgc
  1509541 tggtcttcac cctttccaga aagacgctga gaaacgaatg atccggttcg agcaggcgac
  1509601 gaaatacgcc cgcaccaagg gcatcaagaa gccgatcatc gaagatgcct cgctgacact
  1509661 caaccgcggc aagagcgtcg gcctgctcgg ccgcaacggc gccggcaaat cgacgctgct
  1509721 gcggctgatc gccggcgcga tcaagctcga cggcggtcga atcatccgcc gcggcaagat
  1509781 ttcctggccg ctcggattcg ccggcagctt ccagagctcg atgaccggcg aacagaatgt
  1509841 gcgtttcgtc gcccgtatct acggtgtgaa tacagagcaa ctgatcgcct atgtcgagga
  1509901 ttttgcagag cttggcccct tcttcaaggc gccggtcggc acctattcct ccggaatgaa
  1509961 ggcgcgcctt gcctttgggt tgagcatggg cgtcaacttc gactattatc tcgtcgacga
  1510021 aatcaccgcc gttggtgata caaattttaa gaagaagtgt caggctgtat tcgaaactag
  1510081 gctacaggac tcggatgtgg tcatggtctc gcacagcacc ggtacgatcc gcgactattg
  1510141 cgattgcggt gtggtgctgg aaaaaggcaa gatgacctat tatgagaatg tcgaagacgc
  1510201 aatacgcgcg cacgacaaga acatgaagga aagctaaatg gcggcaagca aagacgcggc
  1510261 tgtgaacaag gctgattccg cgcaagccgc cgggaaggac gtgtcggcaa cggccgcggc
  1510321 gaaaagcaag ggcatagcgg ttctcgaagg gcttctcggc aaggaaagcg cgccggtcat
  1510381 ccccctgccg ggacgccaaa aggcctttcc ccccaagaag acaggctgga aagccggctg
  1510441 gctcaagaag ctccgctggc gtcacgcgat catcggcggc accttcctgg gtcttgttgc
  1510501 cgttcccgcg acgcttgctt cgctctacat ggccttcatc gccgccgacc agtatcacag
  1510561 caccacgtct tttgccgtgc gcagcatcga gggcggcgtt tcaagcgaca tcctgggaat
  1510621 gttcacacag gcatccggcg gcagcacggt ttcggatagc tatatcctca tggattatat
  1510681 cctgagcgag cgcatggcgg cggacgcgga ccgccggttc aagctggaag acgtctacgc
  1510741 gacgcgcgga ctggactatt tctacggtat cggctccgaa ttgccgatcg aggataagct
  1510801 cgactattgg cgcgacatgg tgaacgtcaa tttcgaccac gcctccggca tcatgcaggt
  1510861 aaccgtcaag gcctttgaac cgcggcaggc gcgtgagatc gcgaaattca tcgtggacca
  1510921 gagcgacaac ctcgtgaaca gcctctcgct ctccgcccgc aacgacgtgc tgcgtgcggc
  1510981 gcaggacgaa gtgcttgcgg gcgaagcgcg gctttccaaa gcgcgcgcgg cactgcgcga
  1511041 ctatcgcgac aaatcgcagg aaatcagtcc ggaagagggg gcaaagcttg ccgttcagct
  1511101 catcggatcg ctggagcagc agctgacgca gctcaatgcc gatcttgcga cggccaagag
  1511161 ccagatgggc gaagacacgc cccgaatccg tgtcctcaag acgcgcatag agagcctgga
  1511221 gcagcagctc gacgtggagc gccaacgcct gggcgccggc gaaaagtccg cggccggaaa
  1511281 cgaccccaat tcaccggatg tcgcgggtcg catcgccgag ttcgaggaat tggagacgga
  1511341 gcgcgagttc gcggaacgtg cctatacggc agcgttggga tcgctggaga aggcacgcat
  1511401 cgacgcaaac aaccgccagc gctatctggc acttttcatc gagccgacgc tttcggaact
  1511461 tgctcagtat ccggcgcgcc tgctgaactc gtttctggtg atgctgggac tactatttgc
  1511521 ctggggcatc ggcgtgatgg gatattataa catccgcgat cgggcgtagc tgctgcggca
  1511581 ccccgccgcc gccggtttcg acgtgcggcg agcttcccgt tctcaggcga ctccggcgcg
  1511641 cagcagatcg tgaatatgca ggatgccgac cggtgcgccc gcatcgccga cgaggaagag
  1511701 cacggtgatc ttgtgttctt ccataaactc catggccgca ctggccagca cgtcgcggct
  1511761 gaggacacgc gggttgtgcg acattatggc ctcgaccggt tgcgccagga ggtccgccgt
  1511821 catgtggcgg cgcatatcgc cgtcggtgat gacgccgacc agctttccgc tttcatcgac
  1511881 gatgccgacg acgccgaagc ccttggccga catctcgatg accgcctcgc tcatcgggcg
  1511941 accgacaggg agcaacggca tctgcccggc gccatgcgcc agctcatgga cgaggcgcag
  1512001 ctgcgcgccc agcttgccgc ccggatggaa ggtcttgaag tcctcggcag agaagccgcg
  1512061 ccgctccagc agcgcgattg ccagtgcatc gccgatggcg agctgaagca ttgccgaggt
  1512121 cgtcggcgcc agaccgtgcg gacaagcctc cggcaccttc ggcagcacga gcgcgacttc
  1512181 ggagttgcgc gcaagcgtgc tctcgcggtt ggaacagatc gaaatgatcg gcaccttgaa
  1512241 acgcttggca taggtcagca tgttggcgag ttccgccgtc tcgcccgacc aggaaagcag
  1512301 gaccaatgca tcctgcgcgg tgatcatgcc gagatcgcca tggctcgcct cggtcggatg
  1512361 gacgaaatag gccgaggtgc cggtggatgc gagcgtggct gcgatcttgc ggccgatgtg
  1512421 accgctcttg ccgacacccg aaacgacgac gcggccatct ccatcaccca tcagttcgac
  1512481 cgcattgaca agggcgtccg cgaaggtttc gtcgctcgac agatggtcgg caagcgccct
  1512541 gatgccgttc gtcgccgtcg ccaacgtcct gccgatcgac tccagcacgg tgacaccggc
  1512601 atttccatcc gctttcgcct gcataaatgc gttcaacggt ttttcctttt cgctattccg
  1512661 tggagtcggt tgaccggatt atccacctaa acagaagtat tcgtggcggc gcactggcgc
  1512721 tgtcatacag ctccttaaac agagaaggaa gtgaatgcgg ctgcgactag tgtcttcgtc
  1512781 ccaaaagatt cgtcgtggat gtgcgtatta gacgcattcg tcaagcattg aacgatgcct
  1512841 gttaggtcca taaagactgg gcgagacggg gtggccagaa gccaactaac ctgcctcgaa
  1512901 gccggcaaca gcgccgtcca tgcatctatg aagctcggcc cggagttcct atccacgcaa
  1512961 ttctggtcta attggtccct aatcgtccga acgaacactg caggagtggt taaatggcaa
  1513021 ttttggtaac aggtggcgcc ggatacatcg ggagccacat ggtttggtgc cttctcgacg
  1513081 cgcacgaaga cgttgttgtc cttgatcgtc tctccactgg gtttcgctgg gcggtagcgc
  1513141 cggaagccaa attttatgaa ggcgatatcg gcgattctga gcttctgaac aggatttttg
  1513201 ctagccatga tattgaagca atcatccact ttgccgggtc agtcgtggtt cccgagtctg
  1513261 tcgccgatcc tttgacgtac tatgataata acacggtcaa gtcacgggcg ctgatcgcgt
  1513321 cagcagtgaa agccaaaatc aagtattttg ttttttcttc gaccgcagcc gtctatggta
  1513381 ctccagacgg aaacggcccg gtcaatgaag ccgcgccttt acggccggaa tcgccgtatg
  1513441 gttcgtccaa gctgatgacc gagataatgc tcaaggacgc ggcgtttgct catgacatca
  1513501 catacacggt gctgcgctat tttaacgtcg cgggcgcaga cgttcatggg cgcacaggcc
  1513561 aatcaaccgc aggcgctacg cacctaatca aggtcgcctg cgaagctgca ttggggaaac
  1513621 gcaacggaat tgacgtttac ggcgccgatt atcccactcc tgatggcact tgcatccgtg
  1513681 actttatcca cgtcaccgac ctggtaaacg cacatttaag ggccctggag cggatgcggg
  1513741 caggaggcag ctccattgtc gcgaactgcg gatatggccg aggcttttca gttctggacg
  1513801 tcttgcatca ggtgaagcaa gcatccggcg tcgacttccc cgtaagaatt gtcgagaggc
  1513861 gcccgggtga tgctgtatcc gttgtggcag atccgatgag gattacccga gaacttgcct
  1513921 gggagccttg ccacgatgac cttaacttca tcgtacgaac ctcgctggat tgggagtctc
  1513981 gtttaagccg gagaaataca tattaaaacc agcaagagtg cccttgttgt caaactatgt
  1514041 cttctccgca gatccacggc agggaacagt cgaaaggccg tcgcgaaaat gaccacagca
  1514101 tttgtctttg ggctaagccc ttggaaggac ttcattagaa gctggcttcc cgaagaaagg
  1514161 atatattgcc aaaagcggac aatttcctgg ctggaatttc acgcggtctg ggcaccgttg
  1514221 atattagtat caaaggatcc gaaaatatac gtatggggct acaagcaccc tcccttcatc
  1514281 gaaaggttct caaggctaag tcgcgttaat ctcatccgaa tagaagacgg attcattcgc
  1514341 tcagttgctt tgggcgccag caaggcgcca ccactttctc tttgcttcga ttctcctgtc
  1514401 ctttactacg atcccagctc acagtcgaca cttgaacgcc tcatagagac ctaccacttt
  1514461 tcggcggacc cagctctgct gttgcgagca cgaacgggaa tgaaccgctt ggtcagcagc
  1514521 cggttgagca agtacaacac gtcccaagac gttgatgtcc accgtatcta cggcccgaaa
  1514581 gactgcaagc gaatactggt tctcggtcaa gtagaggatg acatgtcgat catcaagggc
  1514641 tgttcgcgcc tgatgactaa caacgacctc gtccgtctcg ccgttcaaga gaatcccggt
  1514701 gcacaagtaa tctacaagcc ccatccggaa gtattacacg gcaccagact cgcccgatcg
  1514761 agtccggaag aggttagacc aatcgcgcag gttctcgatg acgacattgc tttggcggat
  1514821 gccttcgaaa caatcgatca cgtttatacg atcacctcac tctcgggatt cgaagcgctg
  1514881 ataagaggaa taaaggtaac ttgccttggc atgccgttct atgcgggttg gggacttact
  1514941 gatgatcgcc aatcctgctt gcgccgctcg gcgaagcgta gcgtggaaga ggtgttcgct
  1515001 gcagcctatc tactctatcc caaatatttc catccgcatg agaagaagat gatttcattt
  1515061 gaagaggcgc tggaacttct ccattccatg aaacacgctt cggctactcc ctaaattccc
  1515121 tggacacggt ctgctccgtt atgtttgaaa tcactggggc gagttgcgtg tgatcgtctt
  1515181 cggcagtcga tccaaaaaga cgagcatccg ccagaaccgc taaaaaccgc cagaaccgtt
  1515241 catccgtata cgctcttcac gattcattgc ctctggtcgc acttgttcag aaaaacgaac
  1515301 tcgcggcggt catgcgtgtc tacccaaaat gggctatgtg acaaccaagc cgccgtctga
  1515361 tatttatggc agcttatagt tgctcgaaaa cgcatgcatt ttttattcat tttcaccatt
  1515421 ttttttggcc ggaaacgtcc cggctcccgg aggaaatcat ggctacaatt acgtatcatt
  1515481 tcccagcagg actttaccca aatcaataca acccaccgtt gagtggcgtc agcgttaacc
  1515541 cgtcctttgg cgagctcgtg gacatgagca cggggagtcg ctcaaccact accagcactt
  1515601 cggtgcttta tcggctcgac aacggtctca agatgaagct cgtgggcacg gggttcagtt
  1515661 ttgacgcgag tggcgatgcc gtcggaggaa caatcacatc gattgaggtt cttctgaaca
  1515721 acggcacggg attgatacaa acaattagcg ggctgaatat ttcgcttgaa cttttccaag
  1515781 acgcatcggc cgcgttcgat agttctggac tcgagagttg gctcgcgagc ggcaacgata
  1515841 cgatcaacgg ctccctcggt aatgatgaaa tctgggggcg ccttggaaac gatgtcctca
  1515901 acggcaatgc gggtaatgac cttgtcacag gcggcggcgg tgcagacacc tacgatggag
  1515961 gagccggttt tgatattctg aacttccagg acgcttatga ctccccgaca gcgataagag
  1516021 gcatcaacct caacgccacg gccgggaccg tcgttgatca gttcggtttt tcggaaacct
  1516081 tccagaattt cgaggaattc agaggaaccc agttctcgga ctcgatgatg gggtcctcgg
  1516141 tcgatgagac gttttttggg tttggcggac gcgacaatat caatggtggt gccggcatcg
  1516201 acaccgttcg atacgaccgc gatttccagc gaggcgccac aaagggtgtg agcatcgatc
  1516261 tcagtaccgg tattgcgacc gacggctttg gatctcgaga tactctcacc agcatcgaga
  1516321 atatccgagc aactgaattc aaggatacaa tcgtcggcag ttcggcagcc aacttcctcc
  1516381 gcacgttcgc gggcaatgat tcaatcaatg gcggtggcgg ctcagacaac atgcgcggcg
  1516441 gcataggaaa cgatacgtat ttcgtagaca acaccggcga tatcgttgac gaagccgccg
  1516501 actcgggcgc gggtacggac accgttcaat ccacagtctc gttcaatctc ggcaacaccg
  1516561 cggtcgccaa aggtggcgtg gagaaccttg tgctccttgg caccgggaac ataaacggca
  1516621 ccggcaatgc cttgaacaac accctgagtg gcaataccgg caacaacact ttcagcggct
  1516681 ttgccggcaa cgatacaatt gacgggggcc tcggcaacga cctgatcaat gggggcctcg
  1516741 gcaatgacag cctgaccggc ggagccggct tagacacatt taatttcagc aacgctctgg
  1516801 atgccacgaa caacgtcgac acgatcaacg ggttcgttgt cgcggatgat acgatccgat
  1516861 tggaaaatgc ggtctttacg gggatcgtcg gtaccggcac gttgactgcg gcgcagttcg
  1516921 taacgaatac cactggccta gctgctgacg ccgacgaccg aattatttat gatagcgaca
  1516981 ccggaaggct gctctacgac agcgatggcg acggagcggg cggttctgtt catttcgcca
  1517041 cggtcggcac gaacctcggc atgactgcga gcgatttctt tgttgtgtag ttattcgagc
  1517101 aggaaggccc tcttcatcct tggagaaggc ccccaccatc ctctggtgaa gtgatggcgt
  1517161 catgtaatat ttgtgatgac gcagaccagt tgcgtgtgct tctcccgccg gcagtcaatc
  1517221 cttgtcaggc gcgcgtccgg gaaataccgc cagaatgagg cgagccacgc agcgggcctc
  1517281 atcaccgtga gatgactatg cccgtcgtcg taacaggcga tgacgtgata ctgcagcgcc
  1517341 gctgcactcg cgcaattctc aagaaccctg gtgacgttcc aaggcgtgaa gtgctcaagc
  1517401 acgtctgcag aacaaacaac atccgcttta ggcaagcgat cctgggttac atcagcctgc
  1517461 acgaattcga cattctcagg tcggccgcca aacttcggag acaaggccca gtcgacggcg
  1517521 aagaccttct ccaggtcctc cgcggtggaa agagagaaag ccccgttccc gcaaccgacc
  1517581 tcgaccagcg tctttggttt tgccttcagg atcgacgcct tctcggcgac aagccagttg
  1517641 tttacctggt aagcatcgtt ttcgtcgtgc agctcctgat aatattttgc gcgcattttt
  1517701 gtcgaccgct cgcacggcgt gtctacatcg tctagaatgt atgtagacgg gtcatcgacc
  1517761 cgccaatcca attcgaaaag tagcttcgcc tgccgtgttt ctgattccag cagtgcgtta
  1517821 tgcatcgcaa cagacatttc ccctcccgag cgtttttgat cgttagcctt cagtagcgaa
  1517881 gagtgaagaa aacgcaaagc aagtgtgttg ttgttggtcg ttttgggtaa cgaaaaacgg
  1517941 cgctcgaaac ggaatgatct acagatcaaa cgagccttgc gcttttgtgg gttgacaatg
  1518001 acggccagct tctgaatttt cccggcgctt tcaatgacag aaaggtcgct tccctatgcg
  1518061 gtatgagcaa cccgccctgg tccggaactc ggctgccgag tccccggtcc ttaccgtact
  1518121 gataacgatc agggtcgcag cacattacga catgatcgag cggcttcgct tcaggtcgtt
  1518181 agacactcgg atgcccgact ctgtgacctt ccttgtaatt gacgagggct ccagctttga
  1518241 ggacgcagaa cgattgaagg ccgcatgtgc cgagatcggg ttcgactacg ttcgccacaa
  1518301 caccgagaag gacctgttct gcctcgcagg cgcccgaaac atcggcgctt cactgtcccg
  1518361 ttcgcaattc atcatgttcg aggatgtcga cctttttcct tatcccggtt tctatcagga
  1518421 cattatcgac gagatccacg ttcaggggct cgatacgcac tcgaaccgct tccttactgt
  1518481 cccctgcctc tatctgagcg aacaagcgac cgaggcggcc cttgctggaa cgctatcgaa
  1518541 gaatgaaatt cttcacgacc acctgactgg cgggccgctt gttgatttcg ccctacccgc
  1518601 cagttcggcg ctcgttatca accgcatgtt ttatctgtcg atcggcggct cgaacgatca
  1518661 gttcaagggt tgggggctgg aagatctgga actcgcctac cggctgacgc gtggcaccaa
  1518721 caagttcatg tctccgaagg accatcgttg gctcatcgaa ggtggatacg cccacaaccc
  1518781 aacttatcga ggttggcgcg cacagttccg cttgcatggc gagcttctcg cccgcaaatc
  1518841 gatctacatc tttcacgccc accacccgag agacacggcc tggcgcaacc cggaactcca
  1518901 tcgggcaaac aaagctatat ttcagagcag caatgagtcc ttcgacgcca agggccacac
  1518961 attgccctct ctgccggatg ccaagcgcgg ccggtcgttg atattcgggc gcggcacctt
  1519021 cgcctataac cccgctctcc tgcctttgtg gggcgatctc gaggtgaagg ggtatcaaga
  1519081 cttccaggag cgggacatca tcgagcatgt ccgcgccaac ggcatcaacc gggtgatttt
  1519141 cacaaacccc tacgccaatg acatgcggct ttccgtttac aaccgagtgc gatcggcggg
  1519201 aattcccttc tacgtcgttg agcgtggcgc gcttaccgac tccatgttca ttgacgatac
  1519261 cggcttttgc tgtgagagca cgcgctatcg ccgcgagcac tggcctgcag aacttgacgc
  1519321 cggtcgtctg cggcgggtgc aggattacat ttcggccgaa acttcctcgg gctcggctct
  1519381 tgaaaaacag ggtgagcgca tcggcgcacg tgccgcgctt caaaaactcg gcatcccgcc
  1519441 gcaaaagaag gtcctgtttg ttcctttcca atcccgctcg gacacgaccg tcaatcactt
  1519501 cgccggcccg atcggatcat tcgataactt cgttgacctc gttcgggacg tgacaaagag
  1519561 gctgccaccc gattgggtgg tggtcttcaa aaagcatccg ctttcgtcag ttcaagagac
  1519621 cgtccccggc gccatcgacg tcggcaacat gcacatcaag gacctgatgg aactcacgga
  1519681 ttacgttctg cttatgaact ccggcgtagg cgtcctgtct atcctgttcg accggccgtg
  1519741 catctatacc gcccaagcct tctatgctga cgacgctctg aaccgtggcg catccaaggc
  1519801 tggcgacgtc ctgcgccttc ttaaagaggg cttcaccgtc gaccaagaca gccggctccg
  1519861 gttcttgtcc tacttactcg aagatttcta cagcttcggc aaattcacgg tcaccgagaa
  1519921 gtcgtacacg gacaacgcta ctctctcgat aacagagagg attgactact accgcgtaaa
  1519981 cctccttggt gcgcgcgtcc tcgacaccga cgaccgcgag cggatcctca accccaatgc
  1520041 tcccatctac gatcttttcc gtgagtggat acggagtaat aagcacacag agcggcaggc
  1520101 ttccccatct ggagcccccc aaagtgcgga tgaggcctcg cgcaaaggac ggagtgcgtt
  1520161 tcacgccaag aggtatcagg aggccgccct catgtttgac gccgcctgct cgatacagcc
  1520221 caatagagca acccattacc gcgcagccgc cgaggcgctt ttcgcaatgg ggaacaggaa
  1520281 catcgccctt tcacgtctcg aaaaagcgcg cctcctcgcc cccgacaaca agtcaatcaa
  1520341 gcgccggata cgtgagatga agaggccgcc cttccttcag ttcctctcga agcccttccc
  1520401 catagcaaag gattagggtt attctcgact acccaacaag tatgacgaca cgaggccccg
  1520461 cgccgacgag ataataaacg aggagtttta gcatacctcc tccgcgttca atggagacag
  1520521 cgggcaacgc atgcaggttc atgcgccaca tacctacttg catttcccgt agtcgcctgc
  1520581 gcccttctct ccgagatcgg catctgctcg ctatcgatcg ccgcctaccg tcatcgtgtt
  1520641 ttctgctgcc tatactctat acgggataat tcgtcctcaa ctgaagaaag cgatcacctt
  1520701 cgaagaagcg ctcgaacttc tgcactcgat gaaacgcgcg gcagttgccg cggcctgata
  1520761 ggtcacgctc caagcctatc ctcccgtatc tcccgcgtcg acgtcgtcaa cagcgccagc
  1520821 cccgcaactg cgcagacgag agcgaactcg ataacgtatc ccttgtccag tccgtaggcg
  1520881 cggtattccg ggtagatgct tgccctgaac cacatgatga tgtgcacgag cgggttatag
  1520941 agaatgaaat cgcggaaagg gtgcgggagc gagtccggca ggaaaaagac gcccgatacc
  1521001 atgaagagcg ggcggttgat gatgccgaag atctgctcgt agagcggaaa ccgggcgaac
  1521061 atcacgatgt tgatggtgcc catgccgagg cccagcaggg cggcagcacc cgcggcctcg
  1521121 atcatgccgg caatgtccat cggctgggcg acgccgctga gttcgaggat catcacgaga
  1521181 atgaggatcg tcaccagcgt atcggtcatg agctgcagga taaagcgcga aacgattgca
  1521241 tcgaaggggc tgacgatcgg ataggagaag agcgccttat tggccttcac cgtgccggcc
  1521301 atgaaggaag acatgcgctg atagaaggcg aagggcagat atccgctcgc aaagaacagc
  1521361 ggaaagctca agcccagtgc cggcgtcctg gcgatcgcct ggaagatcac cgtcatcatc
  1521421 gccacatgag cgacagggtc gaagatagcc cagaggtacc cgcccggttt cgagccgaag
  1521481 cgcgtcgaca tttcccgcac gatgagtgcc gccgtcaccc ggagatgttg ttgaattagc
  1521541 ttcacgtccc gcctcgatcg gatttatcga tggatgcggg gtgcttgctg cccctcatcc
  1521601 ggcctgccgg ccaccttctc cccgcaggcg gggcgaagga gacttgcggc gccctctgag
  1521661 cttccatctc accgtttgag gggagaagtt catcctcgag ttcggacccg agacaggggc
  1521721 attccgcttt cgccgccata ttccacaatc cgccgttgct ggcaaatccc tggcgtcgca
  1521781 gccaggcgca caaagaagac cgcctcgatc cattacgatc agggcggcca ggcggaccca
  1521841 ctgggaggtg agttcctttc gctcagcgcc cgccctcgag ttcggcgagg aaagcgctca
  1521901 gctccttttg ctcaacaccc acaagatggc ctttttccgg ataggcgccg gtgcggacgt
  1521961 cggacgcgaa ttcgcggaag gcggcgatgc gctcctgctg caggcggtcg tattcggcgg
  1522021 cgaagttgcg gtaggtcctg gcgtggcgcg gatagtggcc gcgattgctc cccagcacgt
  1522081 cctcggcgaa gagatattgt gcgtcgcagc ccgttcccgc tcccatcgac agcatcagca
  1522141 tcgaggagcg ggcgctgatc gcggcggcga tgccgtccgg caccacctcg atctcggccg
  1522201 caaatgcccc tgcctcttcc agcgccttcg tctggcgcca gacctcgagc gcgcttgcgg
  1522261 ccgtggtgcc gacggcgcga aaaccgccgg tccaggttgc cttggaggga atcagcccga
  1522321 catggccgca gacgggtacc ccctcctcgc gcattcgccg gacagtcgag aggctggccg
  1522381 cgcaatagac ggcatcgcca cccgccttca gcgcctggaa cgcggcgcgc atatagtctt
  1522441 ccgtcgtgac gtagtctcca tattcgagcc ccggaaaggc gaagacggaa ggggccgcct
  1522501 cgcgaaaggc gggcccgagc aaggccggcg gcaccgatac gaggtctatc cccgccttct
  1522561 ccgcggcatc cgcctcttcc agcgtcacga cgcgcagcat ggtgagctgg cgccttcctt
  1522621 tcatcgacag gagatcggct acggtgggtc ggcggtgtct catgacatgc tcctgaattg
  1522681 gaaaggcaga gcgcggctgc gctcaggcgg ccagcagctt cttgagcctg atttcgggtg
  1522741 acgcaagggc ctgcggatcc ggcttcgcgc cggcggcaat cagcatttcg gccaggcgta
  1522801 tatcgcgggc gacggcattg ccggggccga tgccgcttgc ggcgatcagc cggccttcgc
  1522861 catcgagatg gaagaggatg aaggccccct cctccagttc gcggcggacg gtcgcggcgg
  1522921 tgccttcggc gaggcccgat atctgcagcg taagctcata ctgatccgac cagaaccacg
  1522981 gcacgctggc gatatgttcg cccgcgccca tcaggttggc cgcggcgagc gccccctggt
  1523041 cctgggcatt gcgccaggct tcgagccgca cccgccgtcc gccataatgc gaaagcggaa
  1523101 aggagcagca gtcgccggcg gcaagaatgt cggggtccga ggtgcaaagc ctctcgtcga
  1523161 cggcgatgcc gttatcgatc atgaggcccg cagcctcggc gagctcgctg ttcggcactg
  1523221 cgccgacgcc gacgacaaca agatcggcgt caatcctgcc gcccacggcc agcaggaggc
  1523281 ttgcgccgtc tgcgccttcc tcgatggcgg cgatgccggc gccgcagatg atctccacgc
  1523341 cttcctgccg gtgccgctca gcgacgacgg cggcgatctc ctccggtacg ccgcgggaga
  1523401 gaatgcgcgg ctggccttcc acaagcacga cctcggcgcc aagcctgcgg gccgttgcgg
  1523461 caagctccag tccgatgaag ccgccgccga tgatggcgag cttgaggccg ggcgcgagtg
  1523521 cggcgcggat cgtcagcgca tcggcatgcg tcctcagcat gcggatgcgc gcggagttgc
  1523581 cgggcatgcc cgggagcgcg cgcggccggg cgccggtggc aagcagcagc cggtcatagg
  1523641 cgaaggatcg cccgtccgaa agcgtgacgg tcttccgtgc acgtccgatg gcctcgaccg
  1523701 cggtgccggt cagcaccgca atcttcgcct cgcgatagcg ctcgggcgcc gcaacgaatt
  1523761 tcggcgctgc ggcagcggcc aggccatcct tcgaaagcgg cggccgctca tatggaagga
  1523821 gcggctcggc gccgatcagg gtgatctctc cgtcaaagcc tttctccctg agcgcgaagg
  1523881 ctgcccgcgc gccacattcg ccggcgccga cgatcacgat ctgcctcatg ttctcctccg
  1523941 tttgcggccg ggtttcttgt ctacgggccc ctcgccgggt ttgccccttg cctcggtcgt
  1524001 catcctcggg cttgaccgga ggatccattc acaagcgacc cagtctcaag accatctggg
  1524061 catttcgcgc gatcaccctg cacacacgcg tcgtccacct cgcccggttg gtatgccttg
  1524121 cacgtggatc ctcgggtcaa gcccgaggat gacgacctgg ggggtcaagc ccgaggatga
  1524181 cgacttgcgg gtcaggcccg agggtgacga cttggtggac gaccagaaca cgaggatgat
  1524241 ccagaggaag acgttccgcg acgccaatca caacagacct aagacagacc gataaaaacg
  1524301 ctgccggcct ccaccttgac cggataggtc ctgagattga cgcagacggg ggcgcccttg
  1524361 gcctggccgg tcttgtagtt gaagcggccg ttatgcttcg gacattcgat gatgtcgtcc
  1524421 atcaccaggc cgtcggcgag atggatctgc tcatgcgtgc agagcccgtc cgtcgcgaaa
  1524481 tactcgtcgt cggggctgcg gtagacggca aaggtgcgtc cctcatggtc gaaacggatg
  1524541 acgtcctcct cgtcgatctc gtcggccgcg cagacctcga cccagttcga gctcatggtt
  1524601 tcctccttca atggtgattg gtaagcctcg gtccgcttac tcggcggcag aaacgagccg
  1524661 gtcgttgtgc agctcttcgc gatagggcct cgccgtcggc ggcaattcgc gtttcaggaa
  1524721 ataatcctcg ttgcgcagct gccggaggaa tgccgggatc atctcacggt agccgtgaag
  1524781 gatcgaaggg ttcgccgccg gcaggtcgtg cctgatcatg gcgtgcagcc tcggcagcgc
  1524841 gtggtagggc accatcggga acatgtgatg ctccacatgg tagttcatgt tccagtaaac
  1524901 gaagcggctg accgggttca tatagacggt gcggctgttc agacggtggt cggtcacgtt
  1524961 gtcggcaagc ccgccatgct gcaggaggcc ggtcattata tggtgccacg cgccgtagag
  1525021 ccgcggcagg ccgataagca ccagcggcag gattgagccg agatagagcg agagcccgat
  1525081 cgtcgccaga tagatggcaa gccagatgcg ggcgacgcgg atcgccttcg gctgctccgt
  1525141 ttccggaatg aaagtctttt cagcggcgct gatcacgccg aaggcgtttc tgaccatgtc
  1525201 gaccacggca tgccagacat cgatgatgcc gaagatgttg agcacgaggc gcagcagatc
  1525261 cggcggccgc atgaccgcga tctcagggtc acggccgacg atcacggtat cggtgtgatg
  1525321 gcgcgtgtgg ctccagcgcc aggtcacggg attgcgcatg atcatgaagc aggcgatctg
  1525381 gtagacgacg tcgttcatcc acatcgtctt gaaagccgtg ccatggccgc attcatgcca
  1525441 gcggctgtcg gaagcggagc cgtaaagcac gccataggcc aggaagaacg gcaccgccca
  1525501 caggctgccc cagaaataga tgccgaaacc gccgagaagg acgagacttc cgagccagat
  1525561 cgcggtatcg cggatggcgg gtccatcctc gcgcttcatc agctctttca tctgcttgcg
  1525621 gggaatttcc gtgtggtacc actcggccgc ggcgaggccg cttgcaacgg ctgcctcggc
  1525681 atcgcggccg agcaggctgt agtcgcgctt ggtcggaact gtcgtcattc cctgcccccc
  1525741 ctgcggtgcc gcgactctcg tgagatgcgc aaggccgctg cagcctttga acagctccca
  1525801 ctcccgatcg gcgccttcat tcgatgttcc gaggatagtt gactttcgac ggttctcaat
  1525861 gcagtgatga tatattctat caaattcttg catgcgacta cgtcacctgt gagggaatag
  1525921 tttcacggag gagacatgac gagacggccg acgattgcgg atctggcccg cgcatcaggc
  1525981 gtgagcgttg caacggtcga tcgcgtgctg aacggccgtc atccggtgcg cgaggaaacg
  1526041 gcgcgccgcg tctacgatgc ggcgaaggcg atcggctacc acgcggtcgg cctgcttcgc
  1526101 caacgggttt tcgaggacct gccgcaattt cggctcggct ttctcctgca gaagccggag
  1526161 caatcattct acaaggcgct cgcaaaggag atcgaaaacg cggcccttgc ggtgacgcat
  1526221 gtgcgtgccg ttccgcaggt ggatttcgtc gcaagctcca cgccgcaagg gatcatcgaa
  1526281 aagttgaagg ccatggcggc gcgcaatcag gcgatcgccc tggtgtcgcc ggattatccg
  1526341 gccgtgaccg ccgcggtcga ggacctcagg gatcgcggca ttcccgtcgt cgcactgctt
  1526401 tccgactttg ccgccggcgt gcgcgaggcc tatgtgggcc tcaacaatca gaaggtcggc
  1526461 agaacggcgg catggatgat cgccaaggcg gcgaagcgtc cgggaaaggt cgccgccttc
  1526521 gtcggcagcc accgcttcca tggacacgag ctgcgcgaga tcggctttcg ttcgtatttt
  1526581 cgcgaaaacg cacccgagtt cgaagtcctc gacacgatgg tgaacctcga cacgcccgag
  1526641 atcacccatg aggcaacgct cgatctcctg caacgccacc ccgatgtcct cggtttctac
  1526701 gtctgtggcg gcggcatgga gggtgccatt tcggcgatcc gggaggaaag gctcgagggc
  1526761 aagctgctcg tggtcgtcaa cgagctgacg ccggaatcgc gcgcggcact cgccgatgaa
  1526821 acattgctta tggcgatctc gacgcccgcc tcggcattgg cccgggaatc ggtgagcctg
  1526881 atgatcggcg cgatcgaccg ggaggccgcg agcgtgcccg gccaaacctt cctgcccttc
  1526941 gacatctaca cgcccgagaa catctgagcc gcgaaagacg tttgcgaaat cgcgctttat
  1527001 ggaaaacgat agcgaatcaa aggctttcac aaccaggaga gtgcgatgcg gcgcgtcata
  1527061 ctttgtgtac tgggtgctgc cgcgctcgcg gtcaccgcaa ttgccattct gcccagcctg
  1527121 atttccagcg attggatgcg tgccgaactc ggcaggcaat tgtcgtccgc gaccggcagc
  1527181 tcgatcgcgt tcaacggccc cgtcaagttc tccgccttcc cctctctggc ggtcgtggcc
  1527241 aaagatgtga cgctttccgc ggaggctcaa ggggtgactg cggagtttgc ggaggtcacc
  1527301 ggctcggtgg cattttcctc cctttgggcg gatcggctgc gcatcgagga gatcagtgtg
  1527361 gatcggccgg tcataattct tgacgaaaag gcggcggatg aaacgacgcc ggtacaagaa
  1527421 ggcagcggag aggcccgctc gagcgacccg cttcccgatc tcgccgcgct gctcgaacga
  1527481 agcgccatcg actcggtctc gatcacctcc ggcacgttca tacggcgaag cgcagcacgc
  1527541 cgcgaagagg tcgtttccga tgtcgagctg acgctatcta ttcccgatat cgatgacacc
  1527601 ttctctcttt ccgcgtcggc ccgcatgggg gaactgacct acgaggccag cttcacaata
  1527661 tcgaccttgc gttccttgct gggacgccag cctgcggacc tcgacctgac ggtcgaggca
  1527721 gaccccgctc ccgcgccggg gctgaccagc ctttcggcca gcggacaagt gaccctgaac
  1527781 gcgaatggca gctatcagat ccgcggcggt aaagtcgaaa ccggggaaca ggctttcggg
  1527841 ctgaacgcgc tcttcgtgcc cggcaagcgt gcgcgtttcc ttgccgatct cgacgcggac
  1527901 aggctcgacc tgacgccgtt cgtcgatacc acgccggcag cgtcgccgtc gaaagtgctc
  1527961 tctacaggca cgaaaacgga cgccggcaat cgggtaggct tgcagttcct ggccagcttc
  1528021 gatgccgatg tgagcatcaa cgcggctgct atcaccttcg gcgagatgtc cgcgtcggat
  1528081 gtttccgtct cggccgaact caaggacgga aacttggcag tggaactcgg acagttgggc
  1528141 atcgatgccg gtgtcgtgac cgcagacgtc gctacggacg tgcgctccgg cgatcctgtc
  1528201 ttccggggcc gtctctccag cgagggtctc gacataggca gtctttcagc cctcgcggat
  1528261 cgatccgtcc cggtttccgg agccctgacc atcgacgccg atttcgcctt tcgcggtctt
  1528321 gacgcggact ccatccgaaa gacgatcgat ctgaccggga cggtcggcct gcgcgatgca
  1528381 agcttcgcac tgccccttgc cgatgaagcg atgcaggagg tgaaggcgaa gaagatctcg
  1528441 gcccggatcg aaagccttcg caaaccggtg cgcttggagg gccggctgga atggcgcaac
  1528501 aagccggttg acgtggatct gcaaattccc gctgcagata ctctgctgac gggcgatctc
  1528561 gcctcccagg gcatcccgct caagctccaa atgcagatgc cggacgcacg cctgtctctc
  1528621 gatggcagag cggcactgcc ggggacctat gccggaaggc tcgatttttc ggttgccgac
  1528681 ctctctgcct tcctttcggg cttcgggcag agcggtgcgg agagcatcgg cccgctggcg
  1528741 ttcagcggca acgtcgtttc aggcgcgcac ggcgtttctt tcgacaaggc ctccgtttcc
  1528801 gtcaacggca tcgaagccaa gggcaacggc tccgtggaat tcgcgacgcc gctgaagatc
  1528861 gagacgtcgc tagacttcgc ggaactggat cttgcgcggc tcgcgggagc gggcgcaccc
  1528921 gcgcctcagc cgaaagccaa agcaaaagcg aaggcggtta taggcgccga cgttccgctg
  1528981 gatctttcat ctctccgatc ggtcgatgcg acgatcggga tcaatgccga aaagctcggt
  1529041 tatggcagag tctttgccgg gccggtcacc accatgctgg tcgtctccga aggcgtcgca
  1529101 agcctgacgc tgcctgaaag tccgttttac ggcggacatg ttgtcgcgag cctgaaggca
  1529161 gacggctcgc agccggagcc atctatcgcc ttccaggcct ccatctcgcg cgcttcgtcc
  1529221 gcgccgttgc tgaccgacat ggcgggtttc agatatctcg agggcgcatt gaacgcccgg
  1529281 ttcgacgtga ccggtgcggg cggcacgacc aagacgctcg cgaaatcgct gcagggcacc
  1529341 gcggaggtaa ccttcgcgga tggcgccatt cgcggcatcg acatcgccga tgtctacaac
  1529401 aacctcgtgc ggctgatgtc gtccggcttc aaacaggacg acagcaaagc gaccaccttc
  1529461 accgaacttg gggcctcctt tgccatcgag ggtggcgtcg cgcgcaccga ggatattaag
  1529521 cttgtcggcc cgctggtccg catgaccggg aagggcgcgg ccgacctcgc gcaaagcacc
  1529581 ctgaacttcc ggctggaacc ccgcatcgtc gcctcgcttc aaggccaggg cgccgaaatc
  1529641 tccaccgacg gcgtcggcgt ccccgtcgtg gtcgaaggca gcttcgccgc acctcgcatc
  1529701 tacccggacc tttcggactt gctgaagaat cccgatgccg cactggcaaa gctcaaggat
  1529761 ttcggactgc cgatcgacaa gttgccgatt ggcgacctcc ttaacggaga cggcgccggc
  1529821 gcagccgtta aggatttgct cggcggcacg ctggacgagg cgctaaaaga caaggctttc
  1529881 aaacaagaag aacagcagct ctcgatcgag gagatcatcg gtggcgatcc tgcacccaag
  1529941 cccgacgagg cggctgcaga agtcccccca aacgaggaag cggccaaagc cgacgcacca
  1530001 accgaacaac cggcaaacgg aacggaagag ccaagtgagg aggccgatgg tccaatggag
  1530061 ggttttttca agcagctcct gcggtagcgg gagcgaccga acctctcccc gaacgcagcg
  1530121 accgcatggt gcgtaaccta atcggggaaa cgatacttga agtgttcgat ctcggcgccg
  1530181 aatagccgtt cgacgcgttc ccggtcgccg ggtttataat aactgcgaat atccggcctc
  1530241 cttgggttcg ccttcgctct ggtcaggaat cgttcatcaa aaggcagccc gagcctgtcg
  1530301 catacgtggc gtagatcttc cgagaggcgc tcctgccgac ctacgaaatc aacaacaact
  1530361 tcgtcgttct tggtgtagag ctgccacgac ttccaattaa tacgctcctt ctcggctgca
  1530421 cctgcttcga tcaggcagag catttgcgag aagctcggcc gggtatcggc cttcctgtag
  1530481 tgccaattgt aaagagaaac agccctctcg aacgggtttc gcacgaagca aaatttgaaa
  1530541 taatgtttcc aggcagaggg atcgaaggct tcgatttcgc ttgcgctcga atgatccgcg
  1530601 agcctgcctg caaaacgccg gctgagagcg agaccggcca aggaatcgac actgtggttg
  1530661 cggatgaggg tttgagcgat cttaagtgga gacaggtgac agaacatagc aatcagcgcc
  1530721 agccgattgg ctttggctcc attcccgagt gcatccttcc aggacccaag ttgcagatcc
  1530781 catggtccga attcgcgagc aagataggca gaaaccgtgc tgccggcggt tttcggtacg
  1530841 tggatgaaaa tgaacttatg gcgatgggat ataatcactg cctggccact cctcagccgg
  1530901 aaaggtcgaa accgcctgtc accgaaggcg aagacagcag caaacttacg agatgcctcc
  1530961 cgtatctgaa tcctatgcac gatctcggct ccagcaagtc ccggcgggtg ggatcaaggg
  1531021 ttttccgcgc tgcaccttca ctcccgtgcg cagccccacc ccattcaaga tcaacactcg
  1531081 acgatcaagc tgattcctaa ggacgatgcg caatgaggaa gcgggctgac ccaggcggat
  1531141 ttgccgactg tgtcagttgc tcatccacct tgctcgcctg tagggcctcg agcaccagct
  1531201 aagtggcatc ggctcctgca gtcaattcca aaaagccacc ttggatgttg tggaggcgag
  1531261 cgtagacgcc gtccgggcgg cgcgcgagtt cctcgtgcgt cccctcctcg acgaccagcc
  1531321 cctcgttcat cacgacgatc ttgtcggcat taacgaccgt ggaaagccgg tgagcgatca
  1531381 caatgacggt gcggccgctc atcgcttgat ctagtgcctt ctggacagct gcttccgatt
  1531441 ccgtatcaag agccgaggta gcctcgtcca aaagcagaat gggcgcgttg cggacgagcg
  1531501 ctcgcgcgat cgagagacgc tggcgctggc cgccggatag cgtcataccc tgttccccca
  1531561 caggtgtatc gtacccctgt ggctgcgcga gtatgaaatc atgcgcatag gcaagccggg
  1531621 ccgcttcctc tacttgcgcg tccgtcgctt cgggccggcc gtagcggatg ttatcgcgga
  1531681 tagaaccttc aaagaggtaa gcttgttgtg agacataggc gagcccgttg cgcagagact
  1531741 gcttggtaac agcggctatg tcttgcccgt cgatcaggat cacacccgtt tgtggatcgt
  1531801 agaagcgtgg aatgaggctg atgatcgtcg atttgccggc tccagaaggg ccaacaagcg
  1531861 cggtggtctt gccaccttcc gccaggaaac taactccctt aagcacctcc tcgccatcgc
  1531921 catatgagaa ccgcacgtgg cgaaactcga cggtcgcttc ggtgatggcc agtcgactcg
  1531981 caccgggcag gtcccgttga tgcgggacag tgtctagaat ttcgtaaagc atgcgggcgt
  1532041 taacggcagc gcgctctagg gacacctgca ggcgagccaa gcgtcgcacc gggtcgtatg
  1532101 ccaggagaag cgccgttaca aaggcgaaca aggcacccgg ggccacgttg ctgtagatgg
  1532161 tgcggaaggc cgcataggca agcacgcccg aaatcgccag gcccgcaaag gtctccgtca
  1532221 agggcgccgt ccgttcgctc aagcgcgcga tgcggttggc gcggttctcc gcgcccttta
  1532281 tgatcccttc gaccttgcgg cccaactcgt cttccatcgt gaaggctttg acaatggaaa
  1532341 tgccctggat ggtttcctgc atcgcgccta gcacgcggct gttggcctcg accgcttcgc
  1532401 gcgtcgccag acgcagccgc ctcgaaatgt accgaagccc caggagcaac ggaggcgctc
  1532461 ccaagaaggt gataagcgag agcagccagt ccttgcttat catcacgccg acaagaccga
  1532521 ccagagtcag gacatcgcgg gcgaccgacg taactgtcat gttgagcacg tcgcggatgc
  1532581 cggagatgtt ctggttaatc ttggcggtga ggtgcgcgga gcgcttttcc tggaaaaagc
  1532641 caatgctcaa cgccatcaga tgcgtataaa gccggcgctt atagcttgcg acgatgctgt
  1532701 tgccaatttt tgataaagcc acggcttgcc cataagtcgc caggcctctc agcacaaagg
  1532761 cagcaaatat cgagaagcag acgaatagaa cgacgtcgcc gcgcttgttg gcgaaggctt
  1532821 cattgaccac agtttcactg acccacgccg tgaaagccgt cgttgcagcc acgaccatca
  1532881 ggcaggcaat ggcaaaggca tatccgcgga tatggtcgcg gccgttttcg gcaatgacgc
  1532941 gccttaggat cccagtgatc gtttcggtat caacttcgcg ctcttttcga tccttgacgt
  1533001 tcaaatagtc ccgtccccgc aatcacgcat gcgtgcccgt gtactggcgc cgtccccggg
  1533061 tctctatagt gccttgtgac cactttgacc agccgcctcc cttctgcaac ttcacaggct
  1533121 ttcagtgcta acgaggtcgg aagccacccg ctctgccatg acttcctttt caatgttttc
  1533181 cgtgcgggcg aggcttccgc ttcgtgtgag cgagacttca gaggcccttc cgcaatttct
  1533241 tgatgtcaga ctgaaatttg tgcacttata caggagccat tatcctgaac ctgatcgaaa
  1533301 gcacgagaat ttgttcgagg ggataaagtc cgccatacat tggcggctcg ctaaaaaact
  1533361 gaggaattcg aatcctgaca gagctgcaag gcacttggtg ctggcggcta caggacgcgg
  1533421 ggcagacgtt tccagagcga ggcgcgctgt aggatttctc gtggcagaca aaaggtactc
  1533481 ggacgcccgc acgatttgcc gggagcatat atcgacaggc gatccatccg gcttttggcg
  1533541 gcattacgag agcttcgttg acgagctcgc aagctcctgc cgacagcaag aagtgtctgg
  1533601 ctcgagaatc aagattgctc tgttcaacga tacagacttc aggatcaata tcggatgcag
  1533661 gctgaccagc cagggtctca agcaacaaat tctagatgcg ttccccgcgg ctgagattac
  1533721 gtccatcggt ttcaacttcg cagccttcag aaaggagttc ccgaactcca catccgctgg
  1533781 aggatatgaa ctctcggaca ttgagacccg actttccact gcatatggcg aagacgctgt
  1533841 tgaccatata acggccgccg atttcgtgat ccttcagcca gagggatcgt tggaccacag
  1533901 gacaacggca gaagggcttg caaccttctt cactcctatt cttaccgcca ggaagctagg
  1533961 gaagccattt gctgtattga acggaacgat accaatctac gaaggcgaac gatcggacta
  1534021 tctcaaagga ctctttcgcg aactcggcca tgtggccgca cgcgacgaaa tctcggcgga
  1534081 gtattacggg atcgaatttc tggcggatgc tgcatttctt cggatatcgc cggcgcccgt
  1534141 cgcggatcgc gatggttgcc tgataaccac gggcgccaga aacaatgccg aagaagacgt
  1534201 cgaaattcta aaagctgcac tgaagatttg cgaggcgtgg aagcttcggc ctgttgttct
  1534261 tacgcatgca gttgaacgat tctctccata tgaggcagag atcatcgacc gtggcggcat
  1534321 ctttgctgag acagcaagca ttgaacgtgc tgccgagaca atttcaactt gccgacttca
  1534381 cattggtggc cgatatcata tggcgatctt cagtctcctc tgtaacgttc cttctctcct
  1534441 gttcgatgtt aagacccaca agaatcaatg gcttgaacga tactctcctc tgataacgct
  1534501 tgtgcatccg cacacggacc tcgatgccgc ggcagccgcg gtgctgagcg gtggcgtatc
  1534561 gcagggacat ccggcatcaa cgggcgcgga gaaatacggt cttttcctga aacgcgctat
  1534621 ggctgaacag ccgctatagg cggtcccccg ttcgacggcg agcggtcaat cacagcggcg
  1534681 cgcgcgttcc gaactatcgc cattggcggt aatgcgaggc agatagcggc ctaaccgcaa
  1534741 tcggcgagat cgtggtcgtc cgcccctcca ccgcccagtt cagaattgca tttgcctcgg
  1534801 catgcatctt tgctctgatc tcggcccgtt ccacttcact gcagacgaat tgcagcggta
  1534861 tacgttcaaa tgcgctgagt acgccctgct tgaggtccgc atcgggatcg tccctgagcc
  1534921 gttgtgttgc aaggactttc accagaaact caagggtcgc gacccgcaat ccgtcatctt
  1534981 cgaaatgcaa acttccgccc cccggtgact acaccttgac cggagattaa cagcggcgct
  1535041 tgtcagtggc aattcggatt tacaatatac gaagtataag attgaacgcg gcgcaatatt
  1535101 cttggacgga gaactgtctc acgtgtggac gagtaccggc cgccgcccgc tcagcgactc
  1535161 gcagcctgga cgctatctcg catcatgctc agcacgggtc ggaagagtgc tgagagactt
  1535221 tccgcacctt tcgccgacag gtgatctccg tccttataaa gaacggtgcc ttttcgcata
  1535281 acatgacacc tggaggcgtc gcagatttcg ctcatcggat cgacaaccaa ggctccgctc
  1535341 aacttggccg catccgccaa gacccgccgg gccaaggctt ggcgcctgtt ggtgtattca
  1535401 acagaaggag ctatatcgag cgagcgtcca gacgcggccg ctcgtgcgag ggcctcggga
  1535461 acgtcgaatc ccatctccgg tacatccatc accagaatcg ccttcgatcc ctgcccagcg
  1535521 agcttggtca aagtcgcatc aagtcccttc ctgaccggaa tagaccaatc ggtccgggag
  1535581 ggtgcgacgc cagggtcaaa gaagatgccc tgacccggaa gctcttctcg gtggacgtac
  1535641 ttgggccaat agcccaccat gaaaacaaag gcgaactttc tcttctcgat tagcgacatc
  1535701 actgcggaat tgtgatcgac gcatctcttg accgcccccg gaggagcgaa atccgtatct
  1535761 ggcaagggcg ggcacgatcc acgcccaacg aacatgcccg atatacccaa ttggcgagcg
  1535821 gcaagatcta tcgcaggagc gatcgcagcg gcatgagaat ctccccacac gagaaaccgc
  1535881 ggctcgcctg cagtctcgac tccgacccga cagatcttcc ctctccttat ctgaaccggt
  1535941 gtcagacctt ctccatttga atcagtgaaa caccgcttag aggagaaggg gctctcatca
  1536001 taggtggctt ggtaaagcgt tcgggccttt tcgggcaacc tttggggaat gccttccaaa
  1536061 tcattgacaa tgaaaccgaa ggcgaccgca aatgaaatag cagcgctact cacgccgacg
  1536121 atcgcgacac gcgaggatgc cagcacgcca taccgcgcgg gctgctcgac caacctccat
  1536181 gaaatgtagg cgagcgcgaa ggacattgcc acggcggtca gcgcccatcc ggttgtcagt
  1536241 tcgtgaccaa ggccatagcg caagtacacg attatgggcc aatgccagag gtagagagag
  1536301 tatgagatgc gtccgatgaa gaccgaaacg ggattaccca gtaagcgccc tatcgctccg
  1536361 cctcgacagt gtgcgtggat cacaagggcc gtaccgaggc agggcactgc ggcataaata
  1536421 ccgggaaagg gcatatcagg agaatagagg aaaacggcca ggagaactac cagaagtccg
  1536481 agtgccgcca atgcctgtga gccgcggtgc ccataagccg agatcggcgc aatggcaaca
  1536541 aggactccga tcagcaactc ccaaacgcga aaatgcagca agtagaatgc tttttccggc
  1536601 gagtgcacaa tcccccaagt gcttgccccg aaggacaaga gcgcaaccgc caacacgatt
  1536661 gcgcgaatgt gcccacgtgc aaatttgaag gctagaaaaa ccgcgacggg aaaaatcagg
  1536721 taaaactgct cttccacaga cagagaccag gtatgaagca atggcttcat ctctgaggag
  1536781 agatcgaaat agccgctctc gcttcggaac agaatgttcg atgtaaataa ggcagcggct
  1536841 tgtacgctat cgccgaaata ccgaaactcc tgcggcatga gcaaaaacca tgccgcaacg
  1536901 accgaaacgg cgatcatcga gaacaatgcc gggaagatgc gcctcatccg ccgaaggtag
  1536961 aacgacgcaa agctgaagct gccacgctcg aggtcggtga ggatgatcct cgccatgaaa
  1537021 aacccggaca agacaaaaaa gacgtcgacc ccgacgaacc cgcctgagaa cgaactgaag
  1537081 cctgcgtgaa agaggagcac aggcaagatc gccacagctc gcaaaccgtc caggtccggg
  1537141 cgatagtcga agtctcggtg aatcactgcc aaacgcgttc ccatttccgt gatggactgc
  1537201 caaagccaaa gcggcgtttt aagtccacct tcgatcatac ggtgtgctct cctcggaggc
  1537261 tggctcgtca accatctccg ggcggcacca tttgacttag gccacgccgg cacgcagaag
  1537321 atcgtggacg tgcaagatgc ccgacggccg gccaacgtca tcgaccagaa acagcaccgt
  1537381 gatcttttgc gattgcatca tttccatggc tgcactggcc agcattccag gcgtaatcac
  1537441 gcgaggcatg tgcgacatca cggtctcgac ggtgaggagc aaaagatttt gtgacatgtg
  1537501 gcgccgcaaa tcgccgtcgg taatgacacc gacaagctca ccgtcgccac caacgacgcc
  1537561 gacgaccccg aaacccttgc aagacatctg aatgactgct tcgctcatcg gactgccgat
  1537621 cggcaaaagt ggcacagcct cacccgaatg ggccagttca tgggcgagca gcaactgcga
  1537681 accgagcttg ccgcccggat gaaacgtctt gaagtcctcg gccgaaaacc ccctccgctc
  1537741 aagcaaggct attgcaaaag catcccccac cgccaactgc agtattgcag acgtggtcgg
  1537801 agctagacca tgtgggcatg cctccggcac tttcggcaga atcactggga tcgtggagtt
  1537861 gcgagcgatt gtgctgtcgg cattcgacgt gacggaaatg accgggacat tgaagcgctt
  1537921 ggcgtaagtg agcacgttcc cgagttcgac cgtctcaccg gaccatgaaa ggaggatgag
  1537981 caaatcctcg gcggtgatca tgccgagatc gccgtgactt gcttccgtcg gatgcacgaa
  1538041 ataggcggac gtaccggtag aagctagcgt cgcggcgatc ttgcgtccga tgtgcccgct
  1538101 cttgccaaca cccgccacaa cgacccggcc acgcttggag gcgacgagtt cgatggcatc
  1538161 gacaaaacta cggcgcaagg ccgcattctc ctccagacag gccgccagcg catggattcc
  1538221 gtcggcggca gtggcgatcg tacgactgat cgacgccagt attgggtcac tcacaaccac
  1538281 gttcatttct tgactgtccg caattatcga cgaccagtgc taaaggcgtc gcttaccgtt
  1538341 gaagtcttcg aaatcaaatc aagatggcta aattgtgcga tttgcgggta tttcacactt
  1538401 tctgaagcgt gatcgacaga agaattgaga aaattgcaat accggctccg cttctaatcg
  1538461 atgaccgacg gcgaatggac acgtagcctg tcttgtgcga gacaaaagat gtaagtccct
  1538521 taagtgactc tcgcctgact agctgttcaa tggaatttcg cgatgacgat tgaacctgaa
  1538581 gcgcttgaaa aactgcgaga aaagcaccgc cgctggctct cacgactcgg tattgtcgac
  1538641 aagccgtggc tgattctcgg ttccgcgccg tcccccacga ttccgccgga cctgattgga
  1538701 cattgcgcac gcgttgacgt caataacgct ggcaagacgg ccaatgcact gggtctccca
  1538761 cccgccgatt tgacgtttcg aaagcgcaag aaatcgtggg aagagcatcc ctatgtaagg
  1538821 acgagaggcc ttctatggct tcatacgaag tctatctggg tgatgtacct gaaacttctg
  1538881 gcaatgccgc aggttcgcta caagagcctg atgcgcgcca ccaaagctga gcgagaagcg
  1538941 atcgtcaacg tggtgagcgg cgggcttccc tctgatatcg gagaagtcgg caaggtgacg
  1539001 aatggagttg ccgccctgtg ctacgcactt ttcatgggag tgccgtccgt gacgcttgcc
  1539061 gggttctcag tcaccaagat gggccattct tacgacgaca agggcagaat tcgccggcag
  1539121 attgccgaag acaccttcgt tctaaggcgt ttgagagatc gaggaaatgt cttcacgacg
  1539181 gagctggaac tctctgagca tatcggcctc cctttcattc gcgacagaga agacatcatt
  1539241 cgcaacatgg gcggcgcgat cggcgccaac ccggctcagt ggaagtccgc ccaaatatag
  1539301 gcaaaagtgt atgtgtcgcc cgggcgcccg gcgttgtaag gaactgagac gatcgtcggc
  1539361 ttggcgtcgg cgatcctgac gggcatgagt tgcagtaggc ccgtaatgcg cggaggaatc
  1539421 tccgctcgcc tcttaccttc tgccgaccag gccgccaaaa ttcgaccggg gggaaggtgt
  1539481 ctctccgcct cctgagaaaa tccggtcagg atgatcgggg tatcgggaaa ctgaatcctg
  1539541 agattacccg ccacgatcct gtcgtcgacc acgatggcga cccggggcgg acccggatca
  1539601 gcgcgcacca tgcgggcaaa accgctgtaa ggcgtgtgcg cgaaggaata atcgccaatc
  1539661 attggtccga caaagaccct tgcccaaagc atcacgatga cgccgacgga gaggatgccc
  1539721 gaaatcgaaa aaaatgccgg caggcgccgg gcaggatcca ggccggcggc atcgattttc
  1539781 agcgtcagat aaagtgggag aagcgcagta aaaagcgcca accacttcgc acggatatgg
  1539841 gtcgcatcca ttgctacgac gataaacgct atcatgagga agcaggcgac aatcatcctg
  1539901 ccgacgaccc tcgtccatag gctctcggcg cacaggattt tcccaacatc cgcgtagaag
  1539961 atcaatccga agacggcaaa ggtcagtgcg acgcccttga gggccgcaac cgcgagcgaa
  1540021 acaaggcctt ggatcgcgtg cggcagcagc gcgctgtctg ccccctcctt catctcagcg
  1540081 acagtgacac cggtggcatg tccgagatta ttgacgaccc agtaggcatg gggtgccacg
  1540141 atgactgcgc aaaccgcaac tgaggcgagc acccgccagt cgaacagata tttgcgcagc
  1540201 ttcgcctctg gcaggatggc gagcagtgcc gccagcggca agataacgaa attgtatttc
  1540261 gaaatcgccc cgagccccac agcaacaccg acaagcaagt agtggccaac ctttggtggg
  1540321 ttctttagcg cacggaaaaa gccgtaaagg aacagcgaca cggcaaatag cgcggcgacg
  1540381 gtgtgggata aatcgcgctg tgacagcagg aaaaccggtg ggagcgtgag gacgcccagc
  1540441 accgccaccg ccggagcgag cggactgctg gagagaaggc gggccgtaag gccgtagagt
  1540501 aggaggaaga ggaacagaag accgtttttc aaaatggcga gcgacgcgac ggagatacca
  1540561 aatagagcca cgactccata ttgaagccaa ttgtagaagg gcggctggcc tccgtatccg
  1540621 agcagcagat attgtgagag tagtgcttgc tcggattcgt ctatctcaag cgagtccggt
  1540681 ctaagaactt tcaggatgac gctcagcagg caatagccgg cgatcagaac gtataagaga
  1540741 tccggtcttc gaaccagcag actgcgcatt cttcccccat cgccctcgcc cgcattggtg
  1540801 gcaatatcgc gggccagcga caaagctact aggcgaagtt cgtggaaatt gccagacgcc
  1540861 ctcctgtgga cgacggacaa ccaaccacat cgttccgctg cccgaggctt cacgccgccg
  1540921 ccttttttgg ttacacctgg taatgggttg agacgcaaat caaacgtcag ttgaaatcgt
  1540981 ttcgccgctt agaggatcaa gccagaccaa cgacgttttg aagcctaccc atactcggag
  1541041 gtgtaatgac gcaaggtgct catatttaca tcggcttcga cagcaaggaa gtcgtcgcct
  1541101 accatgttct ttgccaaagt attctggaaa agagctccat cccggttacg ttcacgccca
  1541161 tatcgctgaa caatgtcgag aatattttta cgcgcgagcg gaatcctctc caatcaaccg
  1541221 agttttcctt ttcgcggttc ctggtgcctt atctaagccg ttatgagggc tggtcgcttt
  1541281 tcgccgactg cgacatgctc atgcggactg acatcgccca gttgtgggag ttgagagacg
  1541341 atcgctatgc agcgatgtgc gtaaaacacg actacattcc gaaagtcgaa acgaagttcc
  1541401 tgggccaggt ccaaaccaag tacgaaaaga agaactggtc gagcgtgatc ctgttcaata
  1541461 acgctaagtg ccgaaagctc gatttggatt acgtcaatac tgcgtctgga cttgagttgc
  1541521 atcagttcaa atggcttgat tccgacgacc tgatcggcga actccccgca agttggaatt
  1541581 ggctcgtaaa cgagtacgaa tattcaccgg atgcaaagct tgtccatttc acagatggag
  1541641 ggccttactt cgatgagtat aagaacgatg actacgccga ggaatggttc gctacacgtg
  1541701 atcgtgtact tcatgtaacg cagcgctcgg cttaatggcg cgacacccat aagccagttt
  1541761 catcggggcg gcggcgacca actaaccgcc tcacgccccg atgtggtgct gcgatacagc
  1541821 ttcggtgctt taacgtcagc taacgcaatc ccagctcaag cgtcactcag ctttggcgaa
  1541881 ggtggcgtcg tagccaaacc ccatcccgac aagagccgag ataggcgagt ggtttacgac
  1541941 ctcgataccg ctttcggcgg ctatgttccg tgtcatgatg agatggtcga cgatccgctt
  1542001 ttgggccgcg acgattcccg aataggcctt atcggttgtt tcgtagtatc tcggctcatc
  1542061 ggcattactg agatcgatcc ccacgaagcc gatcgagcgg ggcctccagg caacggcaaa
  1542121 ctgtgcggct gaaaccgcga ccgagcctgc ctggaaaatg ccggcaaagg ggtcttcgga
  1542181 aaagccgacg tcgccgtcct cgctcagcct cacatacggc agcttacgca ggtccgcggt
  1542241 gtcccgacgt gccaccccgt acggctttcg cacgttatcg atcaatacga tcggcctgtc
  1542301 tcgcagccat gtgcgatcca actcgcagat cgcccttatg acgctcacag acatcagaca
  1542361 gacgcatccg gcaggaatcc gcttcacgag atcgaagtgt ctccatatga accgttcgtc
  1542421 ttcgattgct atcgccagag gctttgctat tacgctggga aaaaggtgta gcgccccgtt
  1542481 caagagaagg caggaagacc cgtctgcacg ggtcagatcg catcgtgcca cggaggggcc
  1542541 ggagccgacg ataagcacat tcgccggctt ttcttccagg gcgcgcaacg ggctcgtgag
  1542601 acgtcctacc aactcgcctc gatactggat cgtgccgtct cgatcagcgg gtgcaagctc
  1542661 gagcttgagt ccgggaaacc aatcctgaac atgagccctg gaacgaccca ggaggaggcg
  1542721 aaccgcgatc ttgatgcagg aacgtgaaaa tggacgattt gaaatcattg atttctctaa
  1542781 cgcaggcgtt gagtgagcaa aacgacgcag gcaaatatgc aaagtactag cggtttgaac
  1542841 cgctccacaa cggaatgcct aattcctccg aaaccggcgg atccgccgtg aaaatggggt
  1542901 gcccctcact gatcagtttg gaaacgagga atttgtccat ttgaacatga agacgcgtca
  1542961 aacccgttga attgtagacg tgaccgcttg agttcggatt tattcccgtg acgataacag
  1543021 cgggtgctcc gttgtagagg gcaaaaagga ccgcgttcat accgttcgag cacttggaat
  1543081 cggcgtccat ctcgagggag cgcaactcag ccacacgatc cagcaacgcc atccgttcat
  1543141 atcgatcgac gatctccagt cgatcgtatt tatagtcgaa cgctcgcaaa ccttcctcca
  1543201 gacgcgcgcg atcgtccttg cgccagagaa atacgtagag cgtccctgta cgctgccctt
  1543261 tcagcacacg cctgacctcg atcgcgttcg cagtggttcc ttcgacctgg ttgaacatca
  1543321 tcatggtaat atccggcgca tcaacgcccc acttggcgat gaccgattgc gagccgttca
  1543381 cggtaatgat cctgaagctc tcgtcgaatc cggccggcct attggagaca ggcgcggatc
  1543441 ctacaaccac gacggggcta ttgaaccgaa agggtgctgc cggtggatcc ggccgcatga
  1543501 tgcggtactt cagattccgg tatatgcgct tacgcgcgtc ggagatccat gatcccattt
  1543561 gtcctcacca gaaaatcggt actcgtcaat tcgatgctat ttacgccttc gttttcttca
  1543621 aaaacttcgg cttcagccga cgtaaaaatt cgtcggtcga ccgcaacacg tttgttagag
  1543681 atatcaactt gtctacttgt gcatcggtct ggttcagacg cgatgacaag acttctgcga
  1543741 tcgtcgaaga gatttccgca gcgggcaact ccgggaacct tgaagcaagc gatgcgtaac
  1543801 tgtttgtggc gataccaccg cgcatcgtca acttgtccac tctttcgaaa agtcgcaaga
  1543861 agacctgctc gaacgtccaa tcgtggacag cgaccacccg ccacttttcg ctccgctttg
  1543921 ccgagaatcc cgccaggatg atctttgccg gaagcgcctg gtcgaccagc catagggcga
  1543981 tggcgaagcc gctcgtgggg actttggcct gtgggtaaaa atcagcgcag aagccggtca
  1544041 aatccagatg tcccgtgggc gtccccaagt aatcggagct tgtgttcaat ctctcgctcg
  1544101 ccgccagacg aatgttcatg atgcccagga atgcctgcgg cgcgaacagc ttgacgacgt
  1544161 cagcgacctc ttggcggtag acgatatttg cgcctcccgg ttgagcgcgt gaaatcagca
  1544221 aggagtggcc ggaaaattgt tcatcaagaa ccttgtagac cttgttgaag aatacaaaga
  1544281 gggccgtcgg cgggtattcg gcctgaagtt ccttgacgtt aacctgatcg ctgttagcca
  1544341 cgaggataac gtgtgaatac ctcgagaaca aagcacgcca ttgctccgct gtcgtcaaat
  1544401 tctccgtggt tccagaggcg ggaaagtcca tgttcactca tcccaacttc agcgtgcttt
  1544461 cggcgcgcga tttctccatg ctaccgaggc ttggattcca agttcggctc tctccttcta
  1544521 taaaggtgat gtattacaaa tcaaagccgg catgctagtt cggaaggtgc atggtcaaag
  1544581 gtttggaaag tcccttctgc gccgactggg gtgaagggca cgaaggagag ccgttcgatg
  1544641 tttagagacc aaggggcgta gatgtttgga ctgaaggcta aacggcatct tacgagagaa
  1544701 cttgctatca cacctccgtc aggggagttg aaccgacacg ggatcgcaat tgtcgcctgc
  1544761 gtcaaaaacg aggccagtta cattgcggag tgggtgcgct ttcaccaagc agttggtgtt
  1544821 cgacatttcc atctctacga tgacggctcg actgatggaa cggtcgagct gcttcagcgg
  1544881 tcgctgaccg gccaagaact gaccgtcgtc ccttggaaaa tgcgcatgcg ggatgaaaaa
  1544941 agtggtgagt tcttgaacgg acagacgatt gctttcgccc atgcgatctt aaacttcggc
  1545001 ggtaaatatg agcgtatggc tttcatcgac gttgatgaat tcttattgcc caagaaaggt
  1545061 cgaacgttag aagaggcatt acgaggagcc agcggatttc ctaacatctc tttaccctgg
  1545121 catatgttcg gccatagcgg tcatgtctcg cgaccagcag ggcctgtatg cctcaattac
  1545181 aaaatgcggg tctccgatcc catgcagcag aacctcgacg caagcaattt caaatgcatt
  1545241 gtcgatccgg tcgaagtcac gaaagttggc gtgcatcatt ttcaaacacg ttcctacggc
  1545301 gacgaaaccg caaatgattc ggggatggtg gtgccaaaga aaaagcggaa ggctgccgaa
  1545361 ttttactccg cagagttcct gcagctcaat cactattatg cgaaatcgat cgaggagctg
  1545421 aaggaaaaga cagacagagg ttggtctttc gatggttctg cagagaaata ccggaataaa
  1545481 gtcacttcca ccatcacgta tatcgaagcg aacgccatcg aagaccggag catgatcgat
  1545541 tttgtcgacc agaatgggat cgatctcggc cactgattct aagccaaggc gaggagcggg
  1545601 tggaaaacaa gcgtcatatc ggagctaaag tttgcaagat aacgacgaca caacggtaaa
  1545661 aacgtccaac acgagctgcg tgtgggctgt ggcagaaagc aaggcaggaa cgcttacgca
  1545721 gtgccttggc gtgggaaaac aattccatcg tgagccagtg gtcaagttga tcagtcggac
  1545781 tcgcggcttg agaaaattgt tcgaacccag attgtttcgc aaaaaggaac agcgtcccga
  1545841 gctcgtaatc tcctgcggtt tccgcgctga accggcagtc ctcgacataa aggcggccta
  1545901 tggcggcaag cctgtaacag tgcacctcca acgtccgcgc atcgaagggt atgatctcgt
  1545961 tttcgtctct cgtcacgact gggtcgatga attgaaccgg ctcccaaact atcactcgat
  1546021 ggtcggcgta ccgcatcaga ttacctgggc gcggctcgcg cctcttagag atgccgcccg
  1546081 cagacgattt tcgccggacg gccgcccgat agtcgccgtc ttcgtaggcg gctcaaatgg
  1546141 cgcatatgtt tacgacgaca gaacccatca aaacataaag ggcgcaatcg aacaattgga
  1546201 gaaagagggc tggcgcatcg ttgtatcagt ctcacgtaga tctgaagacc acactcagca
  1546261 agccttgtcg acactgaaca gcgaaagcat cgctgtttgg gacaggcgaa gcgagaaccc
  1546321 ctacctcgac tacatggcag ccgctgacgc gttcgtcatt gcaaaggact cgatcacgat
  1546381 gccctgcgag gccctggcga cgggcaagcc tgtctttaca ctcgagttaa cccacgtcgc
  1546441 gggtccgcgg ctggacaagt tcgagcgcta tcaccgggac ctgcatgaaa ctttgcagct
  1546501 gacccggccg tttgagggaa agatcgaacc ctacagctac gaaccgctcg atgaaacgcg
  1546561 ccgcatcgcc tcggtaattc gttccaagct cgaccttcag taagacccta agtgcggccg
  1546621 cacgattatt cgcgccagtg ttccgccacc caaggtgtcg gacggatgta atgtcgcaag
  1546681 tactgaagcg gtcccttgtt cttcctttgc ttcgcatcga agactcccgc gatgtgttcg
  1546741 aacactgtct tgcggggacc cttagttccg aatcggccct ctaccgcgtg ctgtggatgc
  1546801 agaccgcgcg gaaaaatcac gacacgtgca tcatgcggca gacgtggcgc aaagaagtaa
  1546861 ttgagcggaa atggccagcg gcagtcctgg cgaaaatgga gaacccattt ccgaggaaag
  1546921 aactttatcc ccccaggcgc cttgcggctt acgaagcgct gttcgtaacg gtactcgtcg
  1546981 gccacgctct gtggatcgga ccggaacttg tcctgcagcg gcacgagttt tccaaccgga
  1547041 aagcggaaga gggaggtttg cccgaggcgc tcaaagggtg tggtttggtt tctcgccagt
  1547101 attatgtcgt ccgcctcccc tatatcgaag aaaacatcca gcgacgacac gatcacgaga
  1547161 tcaagatcga gaaaaagcac cgggcccttc agtcctccca aggtcggccc ccagagccgc
  1547221 gccttgggcc atatgcctct cgtgttggtc ggcatgctct ccacgtcgag tggcggcaag
  1547281 tcttcgcaaa gtatcgcggg gttcaggcct gcgcgactat cggtaaaaca ggtgaaggtg
  1547341 aaaggcggcg tgatgttgcg agcaaccatc gcgtacagcc ggttaataaa gggggctcca
  1547401 tattttgtgc cccaattgat gcagatgact tgcttcacgc cgccacttgc tgccaaaacg
  1547461 cttgtggtca tttgctccat tcccagttgc tgcacacttc ttgcagccgt cgatcctaaa
  1547521 tccgctagca ggcgtgccga catgggcaca aagactgaac aagcgcgtgc atcgcaagac
  1547581 cctattactt gcaagccgcg ccttcgccaa ggcggtgcga caattcaaaa ttccccagaa
  1547641 acgacggcca actgccgcgc gcctgcttca ctgtctacaa gtgattcccc tccgtcaacg
  1547701 cacgcgttgc accgaatgat accgtccagt ttgtggctag aaatggacgc tggagtgtcc
  1547761 gatctcagct ccgagttcac cggaaagccg ccttgccgct tctggagcag cggctggcga
  1547821 catgctgtgg acctgtttaa cggccgcttt tgggcataga gctacctgcc gtctgccgcg
  1547881 ttgcgccgat tttgctatct tgcctcgtct gttctggtct ggccaccatc atcaaggggt
  1547941 gcacggtcag attttttgag cacgcccttg accttgccat cgttggaagc tccacattcg
  1548001 gtcaagtcag ataaaaggag acttttcgat gtatcacctc aacgtagaag acatgacctg
  1548061 cggccactgc gtcgccacga tcgagaaggc cgtcaaaacc gtcgaccgga acgccagggt
  1548121 cgccgtcgac ctggaggcga aaaccgcctc catcgaatcc ggagtcgcat ccgaggcttt
  1548181 catggccgcg atcgaagagg ctgggtacag agcctccttc aagaaatcct gctgcagcca
  1548241 tgtcggttga cgccgcggtt ttagccgcga cagcaaggca cgctccgccg cggcgggcgc
  1548301 gtgccttggc aaccgcctga cgattgacat ctcctgactt gcagtcctcg aggaatgaga
  1548361 atgtttcaga tcacattgca aaagatgctg attctggccc gtctggcgat cgtcgtgtca
  1548421 ctgacggctt actcattgcc ggctgcctct gcctccatgc atggcggctg gtcaaacacc
  1548481 gaaattgcgc aatcgggcga tcaccacgat gaaacgaaga ttggcgggca ttcgcacgac
  1548541 gatcagaagt cgtctccgga cgatgcaaag aagcttgtga agaccgaatg ctgcaccggc
  1548601 ttctgcgtca gcatggcgat cgtcgcacaa gcgggttccg accgcagacc gcgcgtggcc
  1548661 tccatccgca aattcgccga tgacgcccgg ccgaagggcg aactgcctcc cctgcaccgc
  1548721 ccttcgagta tctgaataga tctcacccgt tctcttacgg gtccaacgcg cgtttgcgag
  1548781 catgatttct ctcatgcgcc gctgcaacct cctatttgga taaaaccatg aaacaattgt
  1548841 tcttcgtggc cgccctgtcg cttcttgcga gcggatgcgc cgccacattg cctcccgatg
  1548901 tcattgcgtc gggcgacctt gccgcctccc agtctcaggt ccgccccctc agatatgcga
  1548961 gcccggtttc aggatacacc caccgcgttc cggtcgatcc ccagccgtgg ggcaaccgga
  1549021 acgacgcaca aactccggaa ggagacgcgt catgatgaga gccaatgtca aacgggctgc
  1549081 ggccctcgcc ctgccacttg tgctcggcgg ctgcgtgtcc gcgagcgaat atgcagcgaa
  1549141 gaacgccggg ttctccgcgg tcgaggccaa gactgccgag gccgtaagaa agcagacggt
  1549201 ctggatacag aaccagcagc acgcacgtgt cgtatccgac cgcgtgaaga cgctgatggc
  1549261 taagaaagcg atcgatgtcg agacggcggt tcaggtggca ctcctcaaca acagggggct
  1549321 gcaagccgcc tacgccgact tgggggattc cgctgccgat gcctggcaat cgacgatgct
  1549381 cgtcaatccg acggtctcgg tcggcctgac cgggatcggc acgccgggcc tcgaagcatt
  1549441 caagtcggtc gaaggcatga tcgccaacaa catcctggcg ctcgccacgc gagaacggga
  1549501 catcgcaatc gccgacaccc gtttcaggca ggcacagttg aacgcggcac tgcgcaccct
  1549561 gcagctcgcc gccgacacgc ggcgcgcctg gatcaatgcg gttgccgcct gggaaacggt
  1549621 ggcccagctc aaccaggcgc aggccgcagc cgacgcagcg tccgagcttg cccaggagct
  1549681 tggcaagagc ggcgcactca cgaaagaggg gcaggcccgc gagcatgttt tctctgccga
  1549741 actggcgggg cagacggcaa aggcgaggct ggaggcaagg ctcgccaagg aagagctgac
  1549801 gcggctgatg ggcctgtggg gttcgggtat cgactatcag gttccgaacc gtctgccgcc
  1549861 gttgccgaag ggaataatga agcgcgaccc gatcgaggcg gaagcattgc agcgccgcgt
  1549921 cgatctgcag atggcgaagc tcgacctcga agcgaccgcg agatcctaca agctgacgga
  1549981 agcgacccgc tacgtcacgg acctcgaact cctcacggga ttcgagaccg agcgggaact
  1550041 cgaggacggc gacatcagga gcgaaacgac cggacaggcc gaactcgaat tcgtcattcc
  1550101 gatcttcgac agcggcagag cccgcatgcg caaggcggaa cttgcctata tgcgggcggc
  1550161 gaacctcctc gcggagaagg ccgtcaacgt ccgctcggaa gcgcgctcgg cctatcaggc
  1550221 ctaccgcgcc aactacgaca ttgcccggca ctaccgcaag agcgtcgtgc cgctgcgcac
  1550281 caggatcgcg gaggaatccc tcctcacata caacgcgatg atcaccaaca ccttcgagct
  1550341 gctcgccgac agccgcgaga aggtcaatgc gaacctgctg gccgtcaacg ccaagcgcga
  1550401 cttctggctg gccgaagcca atctcgcccc cgccgtctac ggcggcggcg cgggtgccgc
  1550461 cgccgtcgaa atcgaagtcg cggcagccgc cgagagcggt ggtggcggcc actgagaaag
  1550521 gaacaggcca tgttcaacag aagacaacta ctcggcgcga gcgccgccct ggtatcgacc
  1550581 gccacctggg cgaagtcgtc caatatgggg ctgccggaag ccgccgtgat ggagacggcg
  1550641 gagacccagc cgccgctaaa gcccacctcc ggccccggct acaacccggt ggtcacgctc
  1550701 aacggctgga ccctgcccta ccggatgaac aacggcgtca aggaattcca tctggtcgcc
  1550761 gagccggtcg agcgtgagat ggccgagggc atgaccgcct atctctgggg ctataacggc
  1550821 cagtcgccgg gtccgacgat cgaggcggtc gaaggcgacc gggtccgcat cttcgtcacc
  1550881 aacaagttgc cggagcacac gacgatccat tggcacggca tgatcctgcc gtccggcatg
  1550941 gacggggtcg gcgggctgtc gcagccgcac atccccgtcg gcaagacctt cgtctacgag
  1551001 ttcgatctcg tgaagtcggg caccttcatg taccacccgc attccgacga gatggtgcag
  1551061 atggcgatgg ggatgatggg tttcttcgtg atccatccca aggacccgaa gttcatgccc
  1551121 gtcgaccggg acttcgtctt cctgctcaac gcctacgaca tcgatcccgg ctcctacgtg
  1551181 ccgcgcgtca tggaaatgac cgacttcaac atgtggtgct ggaacagcag gatattcccg
  1551241 gacatcagcc cgctcgtggt ctccaagaac gaccgcgtgc gggtacgggt cggcaacctc
  1551301 accatgacca accacccgat ccacatgcac ggctacgact tcgaggtcac ctgcaccgac
  1551361 ggcggctggg tccgcccgga ggcgcgatgg ccggaggtca gcatcgacat tccggtcggc
  1551421 gcgatgcggg cctacgagtt cgacgccaga tacgagggcg attgggcgat ccactgccac
  1551481 aagtcgcacc acacgatgaa cgccatggga catgacattc cgaccttcat cggcgtcgac
  1551541 aaatcgaagg tcgcagagaa gatcaggaag ctccgcccgg aatacatgcc gatgggcacc
  1551601 aaaggcatgg ccgacatggg cgagatggaa atggagattc ccgaaaacac cataccgatg
  1551661 atgaccggat ggggaccgca cggtccgatc gaaatgggcg gcatgttctc ggtcgtcaag
  1551721 gtgcgcgagg gcatttccgc gggcgattac tctgatcccg gctggtacga aaacccgccc
  1551781 ggaacgcagg cgtgggagtg gacgggcaaa ctccccgacg cgatcaaagc caaggacgcc
  1551841 aagacccaga tcacgccgaa acatggaaac cacggctgat ccagcatgcc gatgttcaac
  1551901 caacctaagg atcacacaat gaaagctcat atcttcggac ttctcgtcgc ggcgctcgcc
  1551961 accccggcgc tcgcttccgg cagtcacgag ggcggtcatg gcgaagccat ggctgtcggc
  1552021 gagcccggca agaaagcaag cgccacccgg acaattgagg tcacgatgaa ggagacggac
  1552081 gacggccgga tgatcttcac gccatcgacc ttcaaggtca gcaagggcca gaccatccgc
  1552141 ttcgcgatca agaacgccgg cgggctcgat cacgagttcg tgctcgacca ggaggacaag
  1552201 atcatggagc acaaggcggt gatggagaag ttcccggaga tggagcacga cgatccgaac
  1552261 gccatccgtc tcgccgccgg agagtccggc gagatcatct ggaagttcac gaacgacggc
  1552321 acgttcaaga tcgcttgcct ggtgccgggt cactacgacg tgggcatgca cggcgacgtc
  1552381 accgttgcca agaagtgacc atcgaaagga gtccaacatg aaatgcctca tcaagctcac
  1552441 gctcgccact gcgctcgccg tcggaacagc ctacggcgcg ctcgcacagg agttcacaaa
  1552501 ggccaccgtc aagaaggtcg atgtcaaggc gaagaaggtc acgttaatcc atgaggagct
  1552561 caagaacctc aacatgccgg cgatgacgat ggtgtttcgc gctcaggacg agacgatgct
  1552621 ggagaagctg aaggaaggtg cgaatgttga attcgttgcc cagcgcgtca acggcaggct
  1552681 gactgtgacg gaggtcaagt aagtcacagg acgcggccgg cgttcggccg cttccctctt
  1552741 gttcttggcc gacacctcgc cgtggatgtc cggttcagat cttatgcaat aagatcgacg
  1552801 cgtctcgtcc ttgtctctcc atccggggtt tatttgcaaa cctcgggaag acgcatcgcc
  1552861 ggcttttttt ggcagcctga cgaaagaaac gacagataaa cttccgtgcg ctggcaccgc
  1552921 ctgggcctgg tcttggtatc tgcgtgcatt cttaatatgc ctaccctaga gctatgatta
  1552981 tccaaatccc acccaacaca agatggctgt tagattaggc gaaaaggaaa tcggccttcg
  1553041 aaaactgcgc ggcgctgagg gtgccaatag ggtcgtccac aaggatggag aatacgcgac
  1553101 cgacggagtc gttgcccttg ataagcacgt cgccgcccgt ggtgtcataa gcaaagacag
  1553161 tgccgttggc accggaactg gaatagcgag tcacccctag gttctcgata actaggatgt
  1553221 cgaagccgtc ctggaaatcc ataaccgaat cctgaccgct gagcgtgggc gttcctttaa
  1553281 agacaaagcg atcggaatca gccccgcccc aaagtatgtc gcttcccgcc tcacccacga
  1553341 gggtgtcttt ccctgcgtca ccgcgcacga tatcgttgcc attgccgcca tatatcaagt
  1553401 cattgccgtt gccgccgtgg aggatgtcgg cacctgcttc gcccgacagg atgtcatcgc
  1553461 cgtcatcccc gtatgccaga tcgttgccgg cgcccactgc gatcttatcc ttgccgacgc
  1553521 caccataggc gacgtcgatg ccgccctcgg agtccagcac gtcatttcca tcgccaccgt
  1553581 caaggaagtt atccccattg ccgccgtcga cgatgtcgtc ccctataccg ccatagacct
  1553641 tgtcgttgcc cgcctggcct ttcaacgcat cattgccctc ttcaccatag atcgtatcat
  1553701 tgccggcgcc gccaccgacc gcctgctgcg tgagtttccc ggttgcggga tttattcggt
  1553761 tattgaaacc atcattgccc gagccggcgt atatgacgtc gtcgccatcg cctgcgtcga
  1553821 tgtattcttc gcccgcgcca ccatagatcg tgtcgtgtcc tcggccgccg agtatctggt
  1553881 catgaccgtc gccgcccttc acaatatcgt tgccgttgcc accatcaaag gtgtcgttgc
  1553941 ctaatccgcc atccagggtg tcgtcgccta agccgccttc aagacgatca ttgccatcgc
  1554001 cgccttcggc ataatcgtta ccgagaccag cattgatgaa gtcgttgccg gatccaccga
  1554061 aaattctgtc attgccggca tcgccataga ggtaatcgtc gccctcgtag ccccagatga
  1554121 cgtcgtcagc gagaaaaccg cggatcgtgt cggccagatt ggttcccttt agaatcataa
  1554181 agaagtcctc tagccacttg gcggacagcg gataaatcga aagggcgcca acggatctga
  1554241 gggccgaaat cgccggcccg aagatactct gcgttgtaca agagaaagtt accaatacta
  1554301 cttaatttag aaatactcaa tcactttcaa ctctgctttt tcgatctctc gagcgatcaa
  1554361 agagcccagg attgctttct cgcatctgtc gattgggagt taaggtaccg cgttcgcact
  1554421 tcgggcaatc atggcgaaac tctagtggcc gcaagggttt agcgctccgg tttatcttgg
  1554481 cgcggtaccg ctgatcgccg aagttctgcc gagcacgcca cctgctcctt ctgttgccct
  1554541 ttcggatgcg ggtaacgcgt atcgtccagc cgcggtatta atcggaaagc tcgtaggtgg
  1554601 ccggcgcgat ctgatcaccg attttcatcg gtcggaattc gacgtcatcg atcttgcgac
  1554661 gatcgatgcg gacgcgacct ggagcggaaa ccagagcttc aattacattg gcggtaatgc
  1554721 ctggtaagct caacttccgc tccgggatca tatcgggcga cgtcaatggc gatggccagg
  1554781 ctgatttaca aagcaaggtg aacggcgtca cgagccttcg ggtaggcgat tcctgtgatt
  1554841 gcagccccac ttaacattcc tgagcagctt ccaacagaag gtggcttagg tgccgcttac
  1554901 gtgaaccgca gcgagacccg cgatctccgc cgggatcgcg ggtcctgggg caaatagtca
  1554961 gaaacgaaaa gcctcttctc acaggactct ggtcatcggt gatttgcgtg gcatcgccaa
  1555021 aacacctcgc gcaagtcgcc tcggcaacag gatgcacgcc gaagcgccag atcacgcggc
  1555081 tgccctaggg ggtcgatgaa cttcggcagt tcgtcgacgg cagtgatgcc gccggcgtcg
  1555141 aaagcttcct cgaggtcgta agacgcggta agatccgcga cctaacggag atcacatcgc
  1555201 cggttagtgg acggatctga tagctttccg ccttgattgc gcgccgcctt cagccgcctc
  1555261 gcgacatcgc cttcttgaac cgaacgccaa caccaccgcc attctcccgg atgaattcta
  1555321 ttccagcttc ctgaaatgcc gtgatgatac tcgtgagatt attgctgatg ggtacatgag
  1555381 ctccacgttc aaaatcagca atcgtctggc gggacacctt agctgctttt gcaagttctg
  1555441 cttggctcca acccagcatg gctcgcgcgc cacggcattg ctccgttgta agaaaatggc
  1555501 tatccaaggc aaactttctg attgacttct atcattttgt aagaaaaatt accgccagtg
  1555561 atcgaacagg tgcgggaaca cctgttcgat ctgaccacaa ccaagctgtc aggagctcgg
  1555621 atcatggctg attccgacaa tagcagaact ttgcccgcgg tcacccgggg ggatttccat
  1555681 tcctttgtcg ctgcttcttt aacctcagat ccggagcctt cccgattgtt ggacgcgtcg
  1555741 ccggacgcgt gcgatgacga tccggcgttg gaagtctggc gtgagtggtg cgtcgcacgg
  1555801 gagcgtctgg tccaatcgtg cgttaaacaa cagcggctcg agacaaagct ctttgcaacg
  1555861 gtcggctcgc ggctcaccgc acccgaagcc tggaaggccg ccgataagga aatcggatat
  1555921 agcgaggccg tggaggcgga gggacgtgcg gcgaccgccg agggcatcgt ggcggacacc
  1555981 ttgtggaaga cgccggcaca gtcgctcgcc ggcgcaaccg ccaagctcca tgccatcgtc
  1556041 agcaaatggc agccatccgt caccagcgac gagtatccgt ggccacaact gcgcgccgtc
  1556101 atcgccgacc tgctgaagat cgatgcggag atgtcgtttc accgaaacgg gcttcaccgg
  1556161 ctggcggtgc ccgaaacgca cggagcatct cgagggggct gaggagatgg cgcaagacag
  1556221 cgcggagacg attgccagag ttcttcggtc ccggattgtt cattggttcg catcggtttt
  1556281 gaagaaatcc accactttaa gatcgagggc ggccgcaagc ttctccagca tctcgatcgt
  1556341 gggattgtat tcttcacgct ccagcatgcc gatgtaggtg cggtgaacat tcgcccgcag
  1556401 ccccagttcc tcctggctca gctggcggtc gttcctggca attctcagat ttcgtgcaac
  1556461 ggtttctcgg actttcataa ccagagtggt cctgccatgt agcgtattca tctacagagt
  1556521 atactctaca aaagtgaaat ccggatcttt gtggccgacg gctgaacgcg aaatggggag
  1556581 cgccccagcg cggcgatgcc ggctgcggca aaactcaaaa aagagggaac ttcaaaatgc
  1556641 aaattcaaag caggttttgt tcacatcggc ttgccgcatt gctgatctcg ctcaccttct
  1556701 ggagcggtct tccagggcct ggccatgcgc aggaggagct ccggatcgcg acatcgtaca
  1556761 agctgatgac actcgatccg cattacgcaa atctcaacga aaacacctcg ctgctctccc
  1556821 atatctacga acgtctggtc taccaggatg accgtctcga tctgcaaccg ggtctggccg
  1556881 tctcctggcg cgcggtgtcg gacaggcagt gggagttcaa gcttcgcgag aatgtccgct
  1556941 tccatgacgg ctcgcccttg acggcggacg acgtcgtcta cacgatcgag cgcatacgcg
  1557001 atttcctcaa atccccgagc ggcggcttcc ggtcctatct gaccggcatc gaatcggtgt
  1557061 cggcacccga tcccctcacc gtcgtcatca acaccaaggg caatatcccc aacctgccgc
  1557121 tgtcgttctc gtcgatcttt gtgatgaacc ggccggcaca ggggttccag actaccgaag
  1557181 agctcaatgc cggcagggcc ggccaccctc cggtcggcac agggccgtat acattcgaaa
  1557241 gctggagttc cggcgaggtg ctgaagctcg ccaggaacga tgattactgg ggcggcaggc
  1557301 ctgcatggcc gcaggtaacg tttcgggtca tcgaaagccc ggctgcccgc gtggcggcac
  1557361 tcagcaccgg cgaagtcgac ctggcggatg ctattcccgc acgcgacgtt gcctctttga
  1557421 agcagcgcgg cgccaggata gccagcgtcg gcgcggcgcg gatcaacttc ctgcagttcg
  1557481 acgtggagcg agacaggctt cccggcgtga ccgataagtc cggcgagccg atcgccaatc
  1557541 cgttcaagga cgccttggtc cgtcgtgcgc tcgccatggc caccgatcgc ggaattctgg
  1557601 tcgacaagat cctctcgggc tatggcacgg ccgcagccca gctctttccc ggcggcttgc
  1557661 cgggtacctc ggaaaccttg cagccggagg ctccgaagta tgacgaagcc aaggcgcttc
  1557721 tcgcaaaggc tggtttccct gacggtttca acctcattct cgccggacct gccgggcgtt
  1557781 atcccggcga cggcgagagc cttcaggcga ttgcgcaaag ctgggcccgc atcggagtaa
  1557841 aggtgcagcc ggcggcggcg ccgttttcgg ttttcaatac aaagcgtgcc gccggcgact
  1557901 atgccgtctg gtacggcggc gcttccggcg aagcggtgga catcatcctc cacgctctgc
  1557961 tggcctcacc ggaccctgaa agcgggaacg gcgccttgaa cttcgggcat tatcgcaacc
  1558021 aggctttcga cgcgatgctc gcaagggcgg aaagcatcca ggagggccct gagcgcaaca
  1558081 aggcgctcgc cgaagcgacc gagttcgtga tggccgatca gccgatcata ccgctttacc
  1558141 acttccatca catcgtcggc tacggcccgc gcgttgcctc ctatgcgatg catccccgcg
  1558201 gctggaccac ggcgatgcag acgcttgccg cgacggagta agcgatcatg cccctgattt
  1558261 ctgttgtcct cggcaggctg tcgcaagcct tcctgctcct catcgccatg tcgctgatcg
  1558321 gcttcattgg cgtccacagc gtcggcaatc cggtcttcaa tgtcgtcaac atcgaaaccg
  1558381 ccacgccgga ggatatccgc caggccacga tcgcgctcgg cctcgatcag ccgatctggc
  1558441 gccagtacct gcttttcatc aacaatgtcg tgcgcggaaa cttcggcacc tcatatatct
  1558501 atcatctgcc ggccttcgcg ctggtcatga gcaagctgcc ggcgaccctg gagctcgcat
  1558561 gcgtcgccat gcttatcgcg gcgccggttg gaaccggcct cgggctgctc gccggccggc
  1558621 ggagcggcac gatcttcgac cggacggtcc tcagatcgag cgtcttcgcg ctgagtatcc
  1558681 cgtcattctg gctgagcatg atgctcatcc tgctcggcgc catcctgaca ggctggtttc
  1558741 catccggcgg ccgcggcacg acggcgcggt tccttggcca ggagtggagt tttctgaccg
  1558801 ggaacgggct ctggcacatg gtccttcctg ccctggcgct ggcgataccg aacgtcgcct
  1558861 tgatcgcgcg gctttcgcga tcgggcacga tcgaagtcga gaacctggac ttcacgcggt
  1558921 tttgtcgcgc gaaagggctg tcctcccgaa ggatcctgct tcgccacacg cttccaaaca
  1558981 tcagcgtgcc gatcgtgaca atcatcggcc tgcaatttgg cggcatgctc gcttttgccg
  1559041 tggtcgtgga aacgatcttc tcgtggccgg gcgtcggcaa acttctgatc gactccatcc
  1559101 agctcctcga ccggccagtg gtgatggcga cgctgacctt cattgccgtc gccttcgtcg
  1559161 cgctgaatgc cctcgtcgac ttgttctatg ccgtgctcga cccgcgcgtg cgcctgtctt
  1559221 catgaaaggt gacccgtcat gaaagcccaa atcgtaagcg cgcttaagag gcgccgacac
  1559281 ggaccggtcc tgaccgcgtc caagctgctg ctggcaagct acatcctggt tgccatcgct
  1559341 gcacccctaa tcgcgccgca aaacccctat gacccgctgc agatctacgg ctgggaggcg
  1559401 tcctcgccac ccggtacacg tggcagcggc ggctatctct acctgcttgg aaccgacggt
  1559461 ctcggccgag acatcgtcag caccattctc tacggcctgc ggatcagcct ggtggtgtcg
  1559521 atcgtcagta gcgcgctcgc ggcgctgatc gggctgaccg ccggcgtcag tgccgcatat
  1559581 ttcgggaaat gggtcgacat cgcgattatg cggctggtcg accttcagct cagcctgccg
  1559641 acgatcctga ttgcgctcat cgccatcgtc acgctcgggc cgggcataga ccgtatcatc
  1559701 ctggcgttga tcatcgcgca atgggcgacc tatgcccgga tcgcccgcgg cgtcgcactc
  1559761 agcgaagcga acaagcctta catggatgcg gcccgcttga tgcggctgcc aacgtcccgg
  1559821 atcatcttcc gccacctgct tccgaacagc atcgcgcccg ccgtcacctt gataccgatc
  1559881 gaggtcggcc atgccgtcgc actcgaggcg accctctcct ttcttgggct gggcgtcccg
  1559941 atcgacaagc cctcgctcgg ctcagcggtc gcaaacgggt tccagtacct cctgaccggc
  1560001 caatactgga tcagcctgtt cccgggcctc gccctcttcg gcctgatcgc cagcatcaat
  1560061 ctcgtcggcg aagacgttcg ccgcagcctc gatccaagga accatccgct atgacagtgg
  1560121 aacacgtgac gacacccctg ctgcgggtgc agaaccttgg ccttcgccat gtctcgggct
  1560181 cggccacaac accaatcctg tccgacgtga gtttcgaact cgggcgaggc gagatcctcg
  1560241 gcatcatcgg cgagtccggc gccggcaaat cgaccgtcgg caatgccatc ctcgggctgc
  1560301 tttcgcccga gttccagcaa acctccggaa caatcgagtt cgatggcaag gcgatcgacg
  1560361 gcatgactgc cgacgagcgc cagacgcttc gaggacggcg gatatcggcg atcttccagg
  1560421 accacaccgc ctcgctcgat ccgctgatga gcgtcggcgc ccaagtcgaa gaaacctgcc
  1560481 ttacgctcga cagctcgctt tccaagcgcg aggcgcgtgc tcgcgcgatt gatttgcttg
  1560541 cccgtgtcgg cattcccgaa ccggagcggc gataccgcaa ttacccgcac cagttctccg
  1560601 gcgggcagag gcaacgcgtc gtcatcgcca ttgcgcttgc cggctctccc gacatcatca
  1560661 tcgccgacga gccgacgtcg gcgctcgatg cgacggttca gaagcaggtt ctggaacttc
  1560721 taaagatact tgtcgacgaa accggtgtct cgatcatcct cgtcacccac gacatgggcg
  1560781 tgatctccga aatcaccaac cgggttctcg tcatgcgaaa gggccaggtg gtcgaagcgg
  1560841 accgcacagc caccattctc gatcagcccc gccacgacta tacgaagaag ctgcttgccg
  1560901 ccgtcccaag gcttcgcatc ccgacacgca ctgtcaaggc ggaagatgat ggcggccaag
  1560961 caggctcttc cgccatagac ggcgaccaga acccgcttct ggtcgcggaa ggcctttcga
  1561021 aacagttcgc gccgcagggt tttgcttggg gcatcggccg gggcaagccg agattcggcc
  1561081 tgcgcgacgt cggcatccgg ctgccgcgcg ggtcgatcac cgggatcgtc ggcgagagcg
  1561141 gcagtggaaa gacgaccttc ggccgcatcc tcgcgggcct cgatacggca ccgaccggca
  1561201 ggatcacgat cggggaacac gccttcaacg tttcgcgaag tggccgccgc agcggtcttc
  1561261 tcggccgcgt ccagatgatc ttccaggatc catccgtctc cctcaacccc cgcatgacca
  1561321 tcggcgagac gctcgatgaa agcatccgct tcggcgggag gaccggctcc agcaaagagc
  1561381 cggcggacct ggccgcaatg atggatcggc ttggtctgcc gcgaagcctg ctcgcccgcc
  1561441 atccgcatca gctctccggt ggccaaaagc agcgtgtctg tatcgctcgc gccctgttgg
  1561501 cacggcctga gatcatcgtc gcggacgagc cgacgtccgc gctcgacgtc tcggttcagg
  1561561 ccgagatcgt cggtctcctg aaggacacga tcgcggagcg ggcgatgaca atggtcttca
  1561621 tctcccatga cctcgcgatc gttcaagcga tgtgcagctc cgtcttcatc ttcaaggacg
  1561681 gccggatcga ggatttcggg cccaccgagt tcatcttctc gcgatccgac aatccctaca
  1561741 cccgcgccct catcaacgcc cgaccccagc ggttcacatg ctgagcggcg cggcacgcct
  1561801 caccgacagg atccaggctg agacagccaa attttcgaaa cgcgcacgca tagccacaga
  1561861 aggtcacctc aatgaatgac aggttcacat tggccgtaac cggccaatcg ctcatcaagc
  1561921 acgatatccg cgacattcct gctcctgcct tccgtgaggt tcagtccctc cttcgccagg
  1561981 cggatctttc tttcaccaac ttcgagggaa cgatcctcgg tacgcacggg ggttggccgc
  1562041 tcaaaggttc gttcttcggg tgcagcgacc cggccgttct cgatgcactt ggcgccatcg
  1562101 gctttcaggc attgtccctt tcgaacaatc atgccttcga cctcggacca tccggggtgc
  1562161 tttcgacgct ggaggaggtg gagaaacgag gctttttcca tgccggtctc ggccgcaacg
  1562221 cgcgagaagt ctcgcgtgca agcatcgcca cgatcaacca acgccgtatt gccctcgttg
  1562281 cgatggacgg gggccccgga cccgatttca tgtatgccgc ggacgcggac gaaaatcgcc
  1562341 ccgaacgccc cggtgtgaac cggcttcgtc tttcacagct cctcgaggtc gacgatctcg
  1562401 cgtttgagca gatccgggcg gttcgcgaca agatcggcta cactgcgatc gacctcgcca
  1562461 atgacagcca gccggacgat ccgccgcgcc tcgacccgca ggctgaggtc gctatcgccc
  1562521 gctctgtctt caaacggtcc gaccggtacg gacgcggtgt aaggatagat gaggtcgaca
  1562581 tggcaagaaa ccttgccgca atcgcctctg cagccaggga cagcgcactg gtgatcgcct
  1562641 atctccatca tcatcactgg gcttccgact ggtatcagct gcccgaatgg gtgagcggtg
  1562701 tggccaaacg atgcatcgac gcaggcgcgt ccatgtttgt cagtcacggc gcgccggtgc
  1562761 tgcaaccggt cgaaatctat cgaggccggc caatcttcta cagcctgggc aatttcatct
  1562821 tccatgtcca atcggagaag tcgacctgga ccgcagcgga agtctgggaa agtgtcgtcg
  1562881 gggtttgctc ctttgccagc gacaacagcc tcatcaacat cagcttccat cccgtcgtca
  1562941 tcggcggcga gcatggattg gaggacgggg tgttggaacg tcggctggtt ccacagcttg
  1563001 taaccggaga cagcgcggtc aggatccttg gccggcttca ggagcaatcg gcgcgactgg
  1563061 gcgcgcatat agaaatctcc ggcaatgtcg gcaggctgca agcgcggtag tggaccggcg
  1563121 gcgtcggatc tggcgccgcc attcttgtgg gttgttccgg ccacggccga gcaccggcgg
  1563181 ccgcctccgt gtggcgaaca cggcaaccgt tgcaaacgag gaaattaatg cgaacgcgcg
  1563241 acgagctggt cagccggttt ttccggtacg tggccattga gagccagagt aacggtcact
  1563301 ctgcgtccct gccctcctcc cccggccagt tcgagcttgc ctccttgctg gccgaggagt
  1563361 tgcggatgct cgggatcgag gacgtcgtgc tcgatcagca ggcgattgtg accggcgtga
  1563421 agcgtggcac caggcccaat gcgccaagga tcgggttcat cgcgcatctc gatacggtcg
  1563481 atgtcggcct ttctgccatt atccggccgc aaattctccg gttcgaaggc acggaccttt
  1563541 gcctcaaccc tcaggaggac atctggctgc gcgttgccga acacccggaa ctcctcgcct
  1563601 ggtcggggga agacatcatc gtcagcgacg gcaccagcgt gctcggagcg gacaacaagg
  1563661 cggcgatcgc ggtcatcatg acacttctcg cccggctcga tgcgcaaggc gcccacggcg
  1563721 acgtcttcgt cgccttcgtg ccggacgagg aaatcggtct gcgcggcgcc aaggcgctcg
  1563781 atctggcgcg ctttgcatgt gacttcgcct acacgatcga ttgttgcgag ctcggcgaag
  1563841 tcgtgctcga gaccttcaac gccgcatcgg ctgaaatcat ctttaccggc gtcagcgcgc
  1563901 acccgatggc cgcaaagggc accctcgtga accccctttt gatggcgctg gacttcgtct
  1563961 cgcactttga tcgcaaggat acacctgaat gcacgcagga tcggcaaggg ttcttctggt
  1564021 tcaaagagct tgttgcgcat gacagcaagg caacactcaa cgtgctggtt cgcgacttcg
  1564081 atgcggcaga attcgaacgg cgcaagcagc agctccttgc cataacggcg ctggtcaacg
  1564141 cgcactatcc ctccggccgc gtcgagtgcc ggttgaccga cacctaccac aatatcggcc
  1564201 gccgcctgcg cgacgacagc cgcccgggaa cgctgttgtt ccaggctttc gacgcgctcg
  1564261 ggattgaaca aaagcgcatt ccgatgcgcg gcggcaccga tggcgccgtc ctctcggccc
  1564321 ggggaatacc gacgccgaac ttcttcaccg gcgcctacaa cttccattcc cgatttgaat
  1564381 tcctgccggt ctcagctttc gaaaagtcgt tcgaggttgc agccatgctt tgcaaactgg
  1564441 cggcgcagga tgaggcgttg gccgaccgct aacagaacgc gccgcccgtg acggctcgtt
  1564501 atggaattgc ccagaagcgc cacaggatgc caatgcataa tccttctgtg ggacccagat
  1564561 ggacgcctgc gcaccggcgg ttgtggcgga ttctgccgac ggttccgagg gagtggaagt
  1564621 gcggcgcccc gcggcgagcg gagcgccctt gggctggtca gcgggaccag atgagcttgt
  1564681 gctcgccctt gtcgccttgg acgagagagg cgtagaccgg agccgtgaag gacggatcgt
  1564741 cgagcttgag cgagaggtat tctgctcccg tttcgcgggc ggtgcgggtc cagcctgctc
  1564801 cgaactcgac accccctgcg gtgacgcgga agtcgggggc gcggtcgttg ccgcggtcgc
  1564861 agggcctgat ggtggccttg acgttgaggg tgagggtctt gatggtgccc gcataggcgc
  1564921 cggtttcgtc gcgggtgaag gtgccgatct gagccattgt cgtatctcct gaggttgttc
  1564981 gaagccgccc gatgcggcct cgatggcggt cgaaaggcga cggattgggc ggaatgcatc
  1565041 cgcaggaccg cagcgcgagc gaaggacggc ggcagccgag cttgttggct cgcgaggaat
  1565101 gaccgcttgc ggtcagggga agaaggtcgg cggagccgtt gcaggccagg gccggtccgg
  1565161 tgccagacca gcccataaga gaggccgtat cgggggctct cgcggcgtca gcagagaacg
  1565221 acgtgattga tcggtgtctc ctcataagca tgatcagcgc cgccgctcaa ccaggcgcga
  1565281 ggtcccgcgc agtatctttc cagagcggca ggcagggtcc ttgcggcact ttcccagaac
  1565341 cgtcacgctc gcgccgtgtc gaagcgacag gttctccgtc agaacgccga ctagttcgga
  1565401 gcctccggcg aagcagagat gcatcattgc ccgatcacgg atgccagacc gcatcgcgag
  1565461 gtcgggcgca ttgagaatcg cgcaaacctc ttacatccgc ggatgagctt ctggtgatgg
  1565521 cgcttagtcg ggatcgcctg gactcggccg atctactcca gggcagaggg caccttttgc
  1565581 tcgaggtagc gcatgaacgc cctgatagcg gcgaaccgca cgttacgcgt tgccgcgccg
  1565641 ttgcggcgat cctttggtgc ctcagattgc cgggagtata gacaatccgc gcgatctcgt
  1565701 tcgcagttag atgtagggaa cgggtcgact ggtggcccgc ttgagatctg cgggcggtat
  1565761 gttcgtgccg aggatcctcc gcctgcatga agcaagcaac gatgcgccat ggcgtttgcg
  1565821 cttcggctgc cgggagcaac catgtgagaa ccgttgcagc acgaaagtgg tcctcgtctc
  1565881 gctccgctgc aatgcgcgcg aacgcacgaa gataccgttc ggcgtcgtca agcttgtaac
  1565941 cgagcgcacc gcgcggagta agatagcggg tgacgtcagc gctcattatg gcaacctccc
  1566001 gccatgtggc tgcgaaattt cggacaggag cccgatatct accttggcgt agagcgcggt
  1566061 cgtcgatgga aaacggtgac gcaacactgc tccaacgccg gcaaggcttg cgccgttacg
  1566121 cagcatcgcg gtcgccaccg agtggcgcag cacatgcgca cctcgatgga cactttcgat
  1566181 tcccgctctg tctagtgcgt gacacacgat actgagtggg cggatcggtg caatatccgt
  1566241 tatcactggc gtcgacgtac tgcgcggcct tgcccgctca atgtgggcga gaatggcgtc
  1566301 gacgacttcc tggggcagcg gaagccattc ctcgcgccgg actccaatga cgacggccgc
  1566361 caccagagcg ttgcactcgc gcagatacct gacgaatggt gcggcaagcg ccctgtggca
  1566421 cggacagtat cggtaccctg gaacacggat gcagatgcgc tcaaaccagc ggcaagtgtt
  1566481 tcgacgtcga agccggcggt gctcgcccaa tcgccttact atgccaatag gcgcaccacc
  1566541 tcagctattg tcggggccgc ataattccgc tgaacaagcc agtgcttgac catcggcatg
  1566601 tggttgcagc caattgatcc gaacatcggc actccggcga tgtctgcgtt ttcgctttat
  1566661 tactctgttt tcctcgattt gcttgttggt gccggggaag tccggcgtgt cgaacaaatc
  1566721 ggaggttcca aatcccttcc agcggtagcg agcgacctgt ctgttcccga tcttccaaga
  1566781 gagcagcaag gttgcggttc ggatgttgtg ggctcaggga gatggtggcc cgggcggcgg
  1566841 gagggatgat ggccctggct gcggcgctga tcatgcttat gaggagacac cgatcaatca
  1566901 cgtcgttctc tgctgacgcc gcgagagccc ccgatacggc ctctcttatg ggctggtctg
  1566961 gcaccggacc ggccctggcc tgcaacggct ccgccgacct tcttcccctg accgcaagcg
  1567021 gtcattcctc gcgagccaac aagctcggct gccgccgtcc ttcgctcgcg ctgcggtcct
  1567081 gcggatgcat tccgcccaat ccgtcgcctt tcgaccgcca tcgaggccgc atcgggcggc
  1567141 ttcgaacaac ctcaggagat acgacaatgg ctcagatcgg caccttcacc cgcgacgaaa
  1567201 ccggcgccta tgcgggcacc atcaagaccc tcaccctcaa cgtcaaggcc accatcaggc
  1567261 cctgcgaccg cggcaacgac cgcgcccccg acttccgcgt caccgcaggg ggtgtcgagt
  1567321 tcggagcagg ctggacccgc accgcccgcg aaacgggagc agaatacctc tcgctcaagc
  1567381 tcgacgatcc gtccttcacg gctccggtct acgcctctct cgtccaaggc gacaagggcg
  1567441 agcacaagct catctggtcc cgctgaccag cccaagggcg ctccgctcgc cgcggggcgc
  1567501 cgcacttcca ctccctcggg attatcggag cagaatccgc cacaacgaca aatccggcct
  1567561 tcagcgactg gcactgcgca aatccccctc tctgcacaat cagttgtttt gcggtaaccc
  1567621 gctagaagtt gaacttggtg ccgcctggca gaagcgctcc agcgagagcg atcgcgacta
  1567681 cctctcggtc aagctcgatg cccctagctt cccggctccg atctacgcga cgctcgcgga
  1567741 agttgatgga agacgatcca tgaccccgcc ttctcgcgat gcacgccacg gtcgtcgcag
  1567801 gcagcaagag aagcggtgga agatcgaagg cctgtgcacc gagagctaca gaagcgccgc
  1567861 gagcgggctc gtttgccacg aagcggcaat gtatgtgatt acggatgacg acctgcacct
  1567921 tggtgtcttt cccgttcgta gttccggacc aggtggattg atccgcttgt ttgacggcgt
  1567981 attgccccag tcgcatgacg agcggaagaa gcagaaaccc gacctggaag cacttaccct
  1568041 aatcccccca cagtgatctt tcttttggcg ctctcctcgc ctttggttca gggttgcagc
  1568101 gcgacaacca agatgagacg cgtattgcct cacccaagag tgttcccaga gaataatgcc
  1568161 gttgcctcac tcggatgttc tcgaatgcct cacgggttgt tccgatcgtg tccccgcacc
  1568221 tggtgcaggt gacggaggta gcgaagccgc tcgcgagcgc gccctcaata gcgctgtagc
  1568281 gagcgggcgg cttcgcgggc ggtcatcatg ttttgcgtag ggtcgggttg tcgaaggcca
  1568341 acctggcggt atgagcgcgg atgccgaacc ggtattggtc ggtaacgatc tcactgcacg
  1568401 acctctacga tttgcgtctg ccgcgcgaca tcggcgaatg gcccgaacac cagcgcattg
  1568461 gcctgtgtac tgcgccagat cttcattcga cgctgcacgg tccgaatgag gcggtcggga
  1568521 tacacgccgg ggtatttgac ctgcaagcgt tcaagcaact ctcgcgaagt tcgccaaggc
  1568581 tccgcctcga accattcctc gagttcggca gtgacggcga gtagaggatc gggcctccgc
  1568641 cgctctcgct tggccgctgg cttggagcgg gcagtcggtt tcacttcacc accacgccaa
  1568701 gcaatccgta agccagacag aaagtcttcg agcggtaatg cctcgccgtc ggtggcaggc
  1568761 gaaccatcag gcttgtcagc aatttcgacc aatctcgttt gtgccaggcg tatgtcgcgg
  1568821 agcagccgga ccggatcgag tgtcaggtac atcgccttga gccgaaggca tgtatcctcc
  1568881 ggcgtgcgtg ggtcgtcaag cagccgctga tagggcgtgg cgggacgatg atagcgcttg
  1568941 accaccttgg ctccgtcacg gtgcttttct ttcagcttga atgatggctg aaagaaattc
  1569001 acgaacaacc gcattgacga ataaagcttg gccagttccc gagtggctcg cagcccctcg
  1569061 aagcgtcggt atccaacgat cttgcgcacg atcgcgccat tcttctgctc gacaaatgcc
  1569121 tgatcattct ttcggtaggg gcggcaacgg gtgagctcga tattatcgcg caagcaatac
  1569181 tcatgaacac tctcgttcat gaatacactg tcgttgtcgg tgtcgaagcc cagcagcggg
  1569241 aacggcagca acttgcgcag ttcggccaac gcagtgatca gtaccgtttg ctcgcgaacc
  1569301 agcagcggcg cgcattccgt ccagcccgtg gctatatcgg tcaacaccag cgtttgagag
  1569361 aaggcacccc tcgcgtacgg gccggaatga gaaacgagat cagcctcgac aaagccgggt
  1569421 gcggggtcat cccaatccga gaaggttcga acgggaacac tacgccgtat cgctgttgac
  1569481 cctttccggc gccgcggacc cgtggcgctc gctttgatct ccttgaggac ccgatcaatc
  1569541 gtcgctgggc tcatcgccaa gagttgccgg cgcgtctcgc aattcatatc gccgtgtcca
  1569601 tgacgttcca tcgcttcgat cagtgttggc aacagggggt gtagtcgctt gccgcaaatt
  1569661 cgatccgacg cctcccaaac accgacgagc gctgcccgca cgtcatcgcc gtaaacccgg
  1569721 cgccctggcc gaggaccacc cttcgccggt tcgcggtctc ctcgcagcag tcgcatcgca
  1569781 tgcttgcggt gaaagcccgt gagcgccacg aactcgtcta acatcctcgc cttctcggcc
  1569841 cgcccaccta atacatagcg acaactgatc gccgcaacca attccgcacg tgtcgccatg
  1569901 cttaccttcc tcatcacagc tcccgaggtt gattcgtcgg gagcaattta gatgaggcaa
  1569961 taacccattc tcagggagca gttcaggcga ggcaatgcgg atctcagcca gattgtcgct
  1570021 ctacacaggg tcaaggtcca atcgaaaaag gggtgtcttg ctcgggctcg acgcgtgcgg
  1570081 caccgtatgc gccgctccaa gaattgtcga cctctcattc attcttgatc cgctcgcggc
  1570141 ggaatttgct ccaggtcaat attgaagatg cggtcgtggc tggacaggag ctgcggttgt
  1570201 ttcagcgtgg caacaagcgg catatcgaca atgccgtcat tcgttacccg ccttcggcgg
  1570261 ttttaaacgg tcaattccat gacgccgatt gcgatcgagc ggttcgatct cggtgccatc
  1570321 cgacgttggg tgttgccgcc ttcgatcctg gtcgccaacg tctttcgatg aaggtggtca
  1570381 agctagagcc gcctgattac acatcctcag catcactctg agaagaggct tcaccttcgt
  1570441 cggacttcag ccggcggctg agttcgacca acgccccgag caagagcgcg cgtttctcat
  1570501 atcgcaaacc cgccttgacg atcaggccgc ctaacgcgat tttctcccgc gtgtccttct
  1570561 tgcgggcatc agatgtcatc gctctcgcca tccgatcaaa cctcgccatg gccgccctga
  1570621 gccgcgccag acgcgaccgt cgctgttgcc gtgctgggta tgccgtcttc aacccgcttc
  1570681 ctgcctccga tcgaagccgc aagctctccc cgaaagcgtc ttgcgagatg ctcaaacgca
  1570741 tcctgaagct ctgtctcgtc gatctcgatt tcgcccagtc ctgccttcag cgcaatgcgg
  1570801 ccgatgcgct cggcttcgcg ggtttccgcc tgtttcaact gctcctggag cttgccgatc
  1570861 tcttcgcgaa ttttcgagga gggtttcttc attccgtctg tctccctggc tgacatagct
  1570921 tgtctttctg caagccattt ttcggatcag a
//
