LOCUS       NC_017348               2993 bp    DNA     circular CON 08-JUN-2013
DEFINITION  Staphylococcus aureus subsp. aureus LGA251 plasmid pLGA251,
            complete sequence.
ACCESSION   NC_017348
VERSION     NC_017348.1  GI:387781658
DBLINK      Project: 159391
            BioProject: PRJNA159391
KEYWORDS    complete genome; complete replicon.
SOURCE      Staphylococcus aureus subsp. aureus LGA251
  ORGANISM  Staphylococcus aureus subsp. aureus LGA251
            Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcus.
REFERENCE   1
  AUTHORS   Garcia-Alvarez,L., Holden,M.T., Lindsay,H., Webb,C.R., Brown,D.F.,
            Curran,M.D., Walpole,E., Brooks,K., Pickard,D.J., Teale,C.,
            Parkhill,J., Bentley,S.D., Edwards,G.F., Girvan,E.K., Kearns,A.M.,
            Pichon,B., Hill,R.L., Larsen,A.R., Skov,R.L., Peacock,S.J.,
            Maskell,D.J. and Holmes,M.A.
  TITLE     Meticillin-resistant Staphylococcus aureus with a novel mecA
            homologue in human and bovine populations in the UK and Denmark: a
            descriptive study
  JOURNAL   Lancet Infect Dis 11 (8), 595-603 (2011)
   PUBMED   21641281
REFERENCE   2  (bases 1 to 2993)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 2993)
  AUTHORS   Holden,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-FEB-2011) to the INSDC. Holden M., Pathogen
            Sequencing Unit, The Wellcome Trust Sanger Institute, Wellcome
            Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UNITED KINGDOM
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to FR821780.
            Accession number for main chromosome in this genome project:
            FR821779.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2993
                     /organism="Staphylococcus aureus subsp. aureus LGA251"
                     /mol_type="genomic DNA"
                     /strain="LGA251"
                     /sub_species="aureus"
                     /db_xref="taxon:985006"
                     /plasmid="pLGA251"
     gene            89..670
                     /locus_tag="SARLGA251_p010"
                     /db_xref="GeneID:12228606"
     CDS             89..670
                     /locus_tag="SARLGA251_p010"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_005754014.1"
                     /db_xref="GI:387781659"
                     /db_xref="GeneID:12228606"
                     /translation="MNAIQNNISLKKILVVSLSILTILSMVLNFNFKEAQAQNKNTIA
                     DKNVETLNEKEIEKELNYIYGKIIILDKDGTAKDVNLENAKSRYGYVPEGFQKLKNDI
                     ENKKKTSSISPRAVGGNYKNSADCFYSEVLNSYGELLTGNIITAVFEDVKAKNLKGVA
                     KKLAKIGIKGNLAGIAATMVSKDVQCNLKYGLL"
     sig_peptide     89..199
                     /locus_tag="SARLGA251_p010"
                     /note="Signal peptide predicted for pSARLGA251_010 by
                     SignalP 2.0 HMM (Signal peptide probability 0.999) with
                     cleavage site probability 0.994 between residues 37 and
                     38"
     gene            complement(1633..2568)
                     /locus_tag="SARLGA251_p020"
                     /db_xref="GeneID:12228605"
     CDS             complement(1633..2568)
                     /locus_tag="SARLGA251_p020"
                     /inference="protein motif:HMMPfam:PF01446"
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="YP_005754015.1"
                     /db_xref="GI:387781660"
                     /db_xref="GeneID:12228605"
                     /translation="MTKSGKQRPWREKKIDNVSYADILEILKIKKAYNVKQCGNVLEF
                     KPTDEGYLKLHKTWFCKSKLCPVCNWRRAMKNSYQAQKVIEEVIKEKPKARWLFLTLS
                     TKNAIDGDTLEQSLKHLTKAFDKLSRYKKVKQNLVGFMRSTEVTVNKNDGSYNQHMHV
                     LLCVENAYFRKKENYITQEEWVNLWQKALQVDYRPVANIKAIKPNQKGDKDIESAIKE
                     TSKYSVKSSDFLTDDDEKNQEIVSDLEKGLYRKRMLSYGGLLKQKHKILNLDDAEDGN
                     LINTSDEDKTTDEEAKAHSITAIWNFEKQNYYLRH"
     misc_feature    complement(1642..2349)
                     /locus_tag="SARLGA251_p020"
                     /note="Replication protein; Region: Rep_1; pfam01446"
                     /db_xref="CDD:216507"
ORIGIN      
        1 aaaaacttgt tcatattaaa ctcctttgtt tttatgtgtt aatattatat tgaatttatt
       61 taaataacaa aacaaggggg catttacaat gaatgcaatt caaaacaata tatcactaaa
      121 aaagatttta gtagtatctt taagtatttt aaccatactt tcaatggtct tgaattttaa
      181 tttcaaagaa gctcaagccc aaaacaaaaa taccatcgca gataaaaacg ttgaaacttt
      241 aaacgaaaaa gaaatcgaaa aagaactaaa ctacatatat ggcaaaatta ttattttaga
      301 taaagacgga acagctaaag atgttaatct agaaaatgcc aaatctcgat atggatatgt
      361 tcctgaagga ttccaaaaac taaaaaacga catagagaat aaaaagaaaa ctagttcaat
      421 atcacctaga gcagttggtg gaaactacaa aaatagcgct gactgtttct attctgaagt
      481 tttaaactca tatggagaac ttttaaccgg aaacataatc acagcggttt ttgaagatgt
      541 taaagccaaa aacttaaagg gcgtagcaaa aaaattagct aaaattggca taaaaggaaa
      601 cctagctgga atcgcagcta caatggtttc aaaggatgta caatgtaacc ttaaatacgg
      661 gttactttag ataatattta ttccaattgc tttattgacg ttgagcctcg gaacccttaa
      721 caatcccaaa acttgtcgaa tggtcggctt aatagctcac gctataccga cattcgtcta
      781 caagtttagt taagggttct tctcaacttc aataaatttt ctcggcataa atgcatgttt
      841 gattatgcgt gtaactatac cttaaataaa acattaatta tgcactgatt tactaattat
      901 tatcccttac tttcattcac actataatca acaccttaat tctaaatatc tgaagtaatc
      961 gtaattttta atcctaataa aattcgtgac tatcttagtt aaactctgtt taattaagat
     1021 tttttatttt tcgttatcca aaagacgcat ttacatactt aaaaatgcgt cgagctaaaa
     1081 ccaaaattta cgtgtaataa tcgaatatac ttattttgca ttttaagggg gtatttagaa
     1141 cgaactttaa aaatatatag ttttatacct gtatcatctt atttgtttct taaaacgcac
     1201 atatgagcca aataaatata ttctgatttt ataatcaaaa attcgatcaa acccaatgtc
     1261 gatttttcgg acactgccca tttacatgca aattaaaaat tagcataaaa tcctttaaaa
     1321 cttccccatg tttttataaa ttcctgcagg gcgcttttta tcaaaaatcg agaattttta
     1381 atttttctct aagaattccg taagagcata aggagaattt gctatcattc aaaaatgata
     1441 ggtctggcaa agccagacat tccaagggtt ttaagtaatt ttaaagtgat atcataaaaa
     1501 gctgtactgt cacacttttg tgacacaata tattgcgttt gtcacagttt tgtgacacta
     1561 catacagcat ttgtcacaaa aataagacag tactttttta caaaaaatca ataaaaaaga
     1621 catcagtcat cactaatgtc ttaaataata attttgcttt tcaaaattcc aaattgccgt
     1681 aattgaatgt gcttttgctt cttcatctgt tgttttatct tcatcacttg tattaattaa
     1741 attaccatct tcagcatcgt ctaagtttaa aattttatgt ttttgtttaa gcaatccacc
     1801 ataactcaac atacgttttc ggtataaacc tttttctaaa tcacttacaa tttcttgatt
     1861 tttttcgtca tcgtcagtta aaaaatcaga tgacttaacc gaatattttg atgtctcttt
     1921 gattgccgat tcaatatctt tatcgccttt ttgattaggt ttaattgctt taatatttgc
     1981 aacaggtcga taatcaactt gtaatgcttt ttgccataaa ttaacccatt cttcttgagt
     2041 tatataattc tctttttttc taaaatatgc attttcaaca cataacaaaa cgtgcatatg
     2101 ctgattataa ctaccgtcat ttttattaac ggtaacttct gttgaacgca taaatccaac
     2161 aagattttgt ttaacctttt tatatctact caacttatca aatgctttag ttagatgctt
     2221 caaactttgt tctaaagtat ctccatctat cgcatttttt gttgaaagtg ttaaaaacaa
     2281 ccaacgtgct tttggctttt ccttaattac ttcttcaatc actttttgag cttgataact
     2341 atttttcata gcacgcctcc aattacaaac tggacatagc tttgatttac aaaaccacgt
     2401 cttatgtaat ttcaaataac cttcatcggt cggcttgaat tctaagacgt taccacattg
     2461 ttttacgtta taagcctttt ttatttttaa aatttcaagt atatctgcat agcttacatt
     2521 atctattttc ttttctctcc atgggcgttg tttcccactt ttcgtcatat cttttaacgt
     2581 tttattatct tgattttcgg ttatacttct agtagtatta tattgcatat aaaaagaccc
     2641 ccagtattat ttaagattcg acaccttaat aatataactg gggtttttta ttgtcaaatt
     2701 ttcctttcac gcacaaaaac acgtttaaac gctgtaatat caacagttac agatatatat
     2761 ataaaatcga gttatttcta tatagtatca agacaagaag aaactcgttc acactcgttt
     2821 caaaaaaaac aatctatccc ttcttctttt tatgcccctc taaacctaaa taaattaatg
     2881 tgaaaaccaa tgaataaata aaactttcta aaaagtcaaa aggattatca aataaaattg
     2941 aattaacaaa attaaatatt aaaaatacag ataataaaat aatcaaaaag taa
//
