TPANIC_0029 PWY-6386 UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) TPANIC_0029 PWY-6387 UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) TPANIC_0038 PWY-7310 D-glucosaminate degradation TPANIC_0053 PWY-6545 pyrimidine deoxyribonucleotides de novo biosynthesis III TPANIC_0053 PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I TPANIC_0053 PWY-7198 pyrimidine deoxyribonucleotides de novo biosynthesis IV TPANIC_0053 PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP TPANIC_0053 PWY-7220 adenosine deoxyribonucleotides de novo biosynthesis II TPANIC_0053 PWY-7222 guanosine deoxyribonucleotides de novo biosynthesis II TPANIC_0053 PWY-7226 guanosine deoxyribonucleotides de novo biosynthesis I TPANIC_0053 PWY-7227 adenosine deoxyribonucleotides de novo biosynthesis TPANIC_0055 PWY-6339 syringate degradation TPANIC_0057 PWY-6339 syringate degradation TPANIC_0090 PWY-6386 UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) TPANIC_0090 PWY-6387 UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) TPANIC_0094 PWY-1281 sulfoacetaldehyde degradation I TPANIC_0094 PWY-5482 pyruvate fermentation to acetate II TPANIC_0094 PWY-5485 pyruvate fermentation to acetate IV TPANIC_0094 PWY-5497 purine nucleobases degradation II (anaerobic) TPANIC_0094 PWY-6637 sulfolactate degradation II TPANIC_0104 PWY-5381 pyridine nucleotide cycling (plants) TPANIC_0104 PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation TPANIC_0104 PWY-6596 adenosine nucleotides degradation I TPANIC_0104 PWY-6606 guanosine nucleotides degradation II TPANIC_0104 PWY-6607 guanosine nucleotides degradation I TPANIC_0104 PWY-6608 guanosine nucleotides degradation III TPANIC_0104 PWY-7185 UTP and CTP dephosphorylation I TPANIC_0108 PWY-1042 glycolysis IV (plant cytosol) TPANIC_0108 PWY-1861 formaldehyde assimilation II (RuMP Cycle) TPANIC_0108 PWY-5484 glycolysis II (from fructose 6-phosphate) TPANIC_0108 PWY-7385 1,3-propanediol biosynthesis (engineered) TPANIC_0115 PWY-6910 hydroxymethylpyrimidine salvage TPANIC_0115 PWY-7356 thiamin salvage IV (yeast) TPANIC_0115 PWY-7357 thiamin formation from pyrithiamine and oxythiamine (yeast) TPANIC_0122 PWY-7383 anaerobic energy metabolism (invertebrates, cytosol) TPANIC_0168 PWY-1622 formaldehyde assimilation I (serine pathway) TPANIC_0168 PWY-5484 glycolysis II (from fructose 6-phosphate) TPANIC_0170 PWY-6151 S-adenosyl-L-methionine cycle I TPANIC_0170 PWY-6153 autoinducer AI-2 biosynthesis I TPANIC_0170 PWY-6154 autoinducer AI-2 biosynthesis II (Vibrio) TPANIC_0254 PWY-7219 adenosine ribonucleotides de novo biosynthesis TPANIC_0256 PWY-5269 cardiolipin biosynthesis II TPANIC_0256 PWY-5668 cardiolipin biosynthesis I TPANIC_0264 PWY-7180 2'-deoxy-α-D-ribose 1-phosphate degradation TPANIC_0274 PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP TPANIC_0279 PWY-7205 CMP phosphorylation TPANIC_0288 PWY-1269 CMP-3-deoxy-D-manno-octulosonate biosynthesis I TPANIC_0288 PWY-5111 CMP-3-deoxy-D-manno-octulosonate biosynthesis II (from D-arabinose 5-phosphate) TPANIC_0305 PWY-7176 UTP and CTP de novo biosynthesis TPANIC_0305 PWY-7177 UTP and CTP dephosphorylation II TPANIC_0305 PWY-7185 UTP and CTP dephosphorylation I TPANIC_0329 PWY-1622 formaldehyde assimilation I (serine pathway) TPANIC_0329 PWY-181 photorespiration TPANIC_0329 PWY-2161 folate polyglutamylation TPANIC_0329 PWY-2201 folate transformations I TPANIC_0329 PWY-3661 glycine betaine degradation I TPANIC_0329 PWY-3661-1 glycine betaine degradation II (mammalian) TPANIC_0329 PWY-3841 folate transformations II TPANIC_0329 PWY-5497 purine nucleobases degradation II (anaerobic) TPANIC_0340 PWY-2161 folate polyglutamylation TPANIC_0341 PWY-6386 UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) TPANIC_0341 PWY-6387 UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) TPANIC_0342 PWY-7205 CMP phosphorylation TPANIC_0345 PWY-5265 peptidoglycan biosynthesis II (staphylococci) TPANIC_0345 PWY-6470 peptidoglycan biosynthesis V (β-lactam resistance) TPANIC_0345 PWY-6471 peptidoglycan biosynthesis IV (Enterococcus faecium) TPANIC_0354 PWY-6545 pyrimidine deoxyribonucleotides de novo biosynthesis III TPANIC_0354 PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I TPANIC_0354 PWY-7187 pyrimidine deoxyribonucleotides de novo biosynthesis II TPANIC_0354 PWY-7197 pyrimidine deoxyribonucleotide phosphorylation TPANIC_0354 PWY-7198 pyrimidine deoxyribonucleotides de novo biosynthesis IV TPANIC_0354 PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP TPANIC_0357 PWY-6987 lipoate biosynthesis and incorporation III (Bacillus) TPANIC_0357 PWY-7381 lipoate biosynthesis and incorporation (glycine cleavage system, yeast) TPANIC_0358 PWY-5067 glycogen biosynthesis II (from UDP-D-Glucose) TPANIC_0358 PWY-622 starch biosynthesis TPANIC_0371 PWY-7560 methylerythritol phosphate pathway II TPANIC_0386 PWY-6386 UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) TPANIC_0386 PWY-6387 UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) TPANIC_0402 PWY-7219 adenosine ribonucleotides de novo biosynthesis TPANIC_0406 PWY-6386 UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) TPANIC_0406 PWY-6387 UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) TPANIC_0413 PWY-6749 CMP-legionaminate biosynthesis I TPANIC_0418 PWY-3821 galactose degradation III TPANIC_0418 PWY-6317 galactose degradation I (Leloir pathway) TPANIC_0418 PWY-6527 stachyose degradation TPANIC_0419 PWY-5381 pyridine nucleotide cycling (plants) TPANIC_0419 PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation TPANIC_0419 PWY-6596 adenosine nucleotides degradation I TPANIC_0419 PWY-6606 guanosine nucleotides degradation II TPANIC_0419 PWY-6607 guanosine nucleotides degradation I TPANIC_0419 PWY-6608 guanosine nucleotides degradation III TPANIC_0419 PWY-7185 UTP and CTP dephosphorylation I TPANIC_0426 PWY-7219 adenosine ribonucleotides de novo biosynthesis TPANIC_0427 PWY-7219 adenosine ribonucleotides de novo biosynthesis TPANIC_0431 PWY-3961 phosphopantothenate biosynthesis II TPANIC_0438 PWY-7206 pyrimidine deoxyribonucleotides dephosphorylation TPANIC_0441 PWY-5083 NAD/NADH phosphorylation and dephosphorylation TPANIC_0441 PWY-7268 NAD/NADP-NADH/NADPH cytosolic interconversion (yeast) TPANIC_0441 PWY-7269 NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast) TPANIC_0446 PWY-7560 methylerythritol phosphate pathway II TPANIC_0475 PWY-3801 sucrose degradation II (sucrose synthase) TPANIC_0475 PWY-5054 sorbitol biosynthesis I TPANIC_0475 PWY-5384 sucrose degradation IV (sucrose phosphorylase) TPANIC_0475 PWY-5514 UDP-N-acetyl-D-galactosamine biosynthesis II TPANIC_0475 PWY-5659 GDP-mannose biosynthesis TPANIC_0475 PWY-6142 gluconeogenesis II (Methanobacterium thermoautotrophicum) TPANIC_0475 PWY-621 sucrose degradation III (sucrose invertase) TPANIC_0475 PWY-622 starch biosynthesis TPANIC_0475 PWY-6531 mannitol cycle TPANIC_0475 PWY-6981 chitin biosynthesis TPANIC_0475 PWY-7238 sucrose biosynthesis II TPANIC_0475 PWY-7347 sucrose biosynthesis III TPANIC_0475 PWY-7385 1,3-propanediol biosynthesis (engineered) TPANIC_0476 PWY-5482 pyruvate fermentation to acetate II TPANIC_0476 PWY-5485 pyruvate fermentation to acetate IV TPANIC_0476 PWY-5497 purine nucleobases degradation II (anaerobic) TPANIC_0477 PWY-5514 UDP-N-acetyl-D-galactosamine biosynthesis II TPANIC_0477 PWY-6855 chitin degradation I (archaea) TPANIC_0477 PWY-6906 chitin derivatives degradation TPANIC_0478 PWY-7268 NAD/NADP-NADH/NADPH cytosolic interconversion (yeast) TPANIC_0505 PWY-2722 trehalose degradation IV TPANIC_0505 PWY-5661-1 TPANIC_0505|TPANIC_0505|REF_bcmhgsc:TPANIC_0505|GeneID:15851791 TPANIC_0505 PWY-621 sucrose degradation III (sucrose invertase) TPANIC_0512 PWY-7560 methylerythritol phosphate pathway II TPANIC_0518 PWY-6898 thiamin salvage III TPANIC_0518 PWY-6907 thiamin diphosphate biosynthesis III (Staphylococcus) TPANIC_0518 PWY-6908 thiamin diphosphate biosynthesis IV (eukaryotes) TPANIC_0523 PWY-5265 peptidoglycan biosynthesis II (staphylococci) TPANIC_0523 PWY-6385 peptidoglycan biosynthesis III (mycobacteria) TPANIC_0523 PWY-6470 peptidoglycan biosynthesis V (β-lactam resistance) TPANIC_0523 PWY-6471 peptidoglycan biosynthesis IV (Enterococcus faecium) TPANIC_0528 PWY-7219 adenosine ribonucleotides de novo biosynthesis TPANIC_0529 PWY-7219 adenosine ribonucleotides de novo biosynthesis TPANIC_0537 PWY-1042 glycolysis IV (plant cytosol) TPANIC_0537 PWY-5484 glycolysis II (from fructose 6-phosphate) TPANIC_0537 PWY-6142 gluconeogenesis II (Methanobacterium thermoautotrophicum) TPANIC_0537 PWY-7003 glycerol degradation to butanol TPANIC_0538 PWY-1042 glycolysis IV (plant cytosol) TPANIC_0538 PWY-5484 glycolysis II (from fructose 6-phosphate) TPANIC_0538 PWY-6886 1-butanol autotrophic biosynthesis TPANIC_0538 PWY-6901 superpathway of glucose and xylose degradation TPANIC_0538 PWY-7003 glycerol degradation to butanol TPANIC_0542 PWY-1042 glycolysis IV (plant cytosol) TPANIC_0542 PWY-1861 formaldehyde assimilation II (RuMP Cycle) TPANIC_0542 PWY-5484 glycolysis II (from fructose 6-phosphate) TPANIC_0542 PWY-7385 1,3-propanediol biosynthesis (engineered) TPANIC_0547 PWY-7560 methylerythritol phosphate pathway II TPANIC_0560 PWY-1861 formaldehyde assimilation II (RuMP Cycle) TPANIC_0560 PWY-5723 Rubisco shunt TPANIC_0560 PWY-6891 thiazole biosynthesis II (Bacillus) TPANIC_0560 PWY-6892 thiazole biosynthesis I (E. coli) TPANIC_0560 PWY-6901 superpathway of glucose and xylose degradation TPANIC_0560 PWY-7560 methylerythritol phosphate pathway II TPANIC_0568 PWY-2221 Entner-Doudoroff pathway III (semi-phosphorylative) TPANIC_0568 PWY-6507 4-deoxy-L-threo-hex-4-enopyranuronate degradation TPANIC_0568 PWY-7242 D-fructuronate degradation TPANIC_0568 PWY-7310 D-glucosaminate degradation TPANIC_0595 PWY-7219 adenosine ribonucleotides de novo biosynthesis TPANIC_0601 PWY-7560 methylerythritol phosphate pathway II TPANIC_0614 PWY-6823 molybdenum cofactor biosynthesis TPANIC_0614 PWY-6891 thiazole biosynthesis II (Bacillus) TPANIC_0614 PWY-6892 thiazole biosynthesis I (E. coli) TPANIC_0614 PWY-7250 [2Fe-2S] iron-sulfur cluster biosynthesis TPANIC_0616 PWY-1861 formaldehyde assimilation II (RuMP Cycle) TPANIC_0616 PWY-5723 Rubisco shunt TPANIC_0628 PWY-5381 pyridine nucleotide cycling (plants) TPANIC_0637 PWY-2781 cis-zeatin biosynthesis TPANIC_0642 PWY-6749 CMP-legionaminate biosynthesis I TPANIC_0644 PWY-5188 tetrapyrrole biosynthesis I (from glutamate) TPANIC_0647 PWY-6281 L-selenocysteine biosynthesis II (archaea and eukaryotes) TPANIC_0662 PWY-1042 glycolysis IV (plant cytosol) TPANIC_0662 PWY-1861 formaldehyde assimilation II (RuMP Cycle) TPANIC_0662 PWY-5484 glycolysis II (from fructose 6-phosphate) TPANIC_0662 PWY-6142 gluconeogenesis II (Methanobacterium thermoautotrophicum) TPANIC_0662 PWY-7385 1,3-propanediol biosynthesis (engineered) TPANIC_0667 PWY-7193 pyrimidine ribonucleosides salvage I TPANIC_0670 PWY-6386 UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) TPANIC_0670 PWY-6387 UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) TPANIC_0673 PWY-5188 tetrapyrrole biosynthesis I (from glutamate) TPANIC_0681 PWY-7383 anaerobic energy metabolism (invertebrates, cytosol) TPANIC_0732 PWY-1722 formate reduction to 5,10-methylenetetrahydrofolate TPANIC_0732 PWY-2201 folate transformations I TPANIC_0732 PWY-3841 folate transformations II TPANIC_0732 PWY-5030 L-histidine degradation III TPANIC_0732 PWY-5497 purine nucleobases degradation II (anaerobic) TPANIC_0732 PWY-6613 tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate TPANIC_0734 PWY-4202 arsenate detoxification I (glutaredoxin) TPANIC_0734 PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation TPANIC_0734 PWY-6608 guanosine nucleotides degradation III TPANIC_0734 PWY-6609 adenine and adenosine salvage III TPANIC_0734 PWY-6611 adenine and adenosine salvage V TPANIC_0734 PWY-6620 guanine and guanosine salvage TPANIC_0734 PWY-6627 salinosporamide A biosynthesis TPANIC_0734 PWY-6644 fluoroacetate and fluorothreonine biosynthesis TPANIC_0734 PWY-7179 purine deoxyribonucleosides degradation I TPANIC_0734 PWY-7179-1 purine deoxyribonucleosides degradation TPANIC_0735 PWY-101 photosynthesis light reactions TPANIC_0735 PWY-7230 ubiquinol-6 biosynthesis from 4-aminobenzoate (eukaryotic) TPANIC_0741 PWY-5381 pyridine nucleotide cycling (plants) TPANIC_0741 PWY-5653 NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde TPANIC_0746 PWY-241 C4 photosynthetic carbon assimilation cycle, NADP-ME type TPANIC_0746 PWY-6549 L-glutamine biosynthesis III TPANIC_0746 PWY-7115 C4 photosynthetic carbon assimilation cycle, NAD-ME type TPANIC_0746 PWY-7117 C4 photosynthetic carbon assimilation cycle, PEPCK type TPANIC_0780 PWY-5381 pyridine nucleotide cycling (plants) TPANIC_0780 PWY-5653 NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde TPANIC_0794 PWY-5041 S-adenosyl-L-methionine cycle II TPANIC_0794 PWY-5912 2'-deoxymugineic acid phytosiderophore biosynthesis TPANIC_0797 PWY-3341 L-proline biosynthesis III TPANIC_0797 PWY-4981 L-proline biosynthesis II (from arginine) TPANIC_0797 PWY-6344 L-ornithine degradation II (Stickland reaction) TPANIC_0817 PWY-1042 glycolysis IV (plant cytosol) TPANIC_0817 PWY-1622 formaldehyde assimilation I (serine pathway) TPANIC_0817 PWY-2221 Entner-Doudoroff pathway III (semi-phosphorylative) TPANIC_0817 PWY-5484 glycolysis II (from fructose 6-phosphate) TPANIC_0817 PWY-5723 Rubisco shunt TPANIC_0817 PWY-6142 gluconeogenesis II (Methanobacterium thermoautotrophicum) TPANIC_0817 PWY-6886 1-butanol autotrophic biosynthesis TPANIC_0817 PWY-6901 superpathway of glucose and xylose degradation TPANIC_0817 PWY-7003 glycerol degradation to butanol TPANIC_0817 PWY-7124 ethylene biosynthesis V (engineered) TPANIC_0817 PWY-7218 photosynthetic 3-hydroxybutanoate biosynthesis (engineered) TPANIC_0824 PWY-6891 thiazole biosynthesis II (Bacillus) TPANIC_0824 PWY-6892 thiazole biosynthesis I (E. coli) TPANIC_0824 PWY-7560 methylerythritol phosphate pathway II TPANIC_0828 PWY-6012 acyl carrier protein metabolism I TPANIC_0828 PWY-6012-1 acyl carrier protein metabolism II (mammalian) TPANIC_0844 PWY-1042 glycolysis IV (plant cytosol) TPANIC_0844 PWY-5484 glycolysis II (from fructose 6-phosphate) TPANIC_0844 PWY-6901 superpathway of glucose and xylose degradation TPANIC_0844 PWY-7003 glycerol degradation to butanol TPANIC_0861 PWY-6749 CMP-legionaminate biosynthesis I TPANIC_0885 PWY-6545 pyrimidine deoxyribonucleotides de novo biosynthesis III TPANIC_0885 PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I TPANIC_0885 PWY-7187 pyrimidine deoxyribonucleotides de novo biosynthesis II TPANIC_0885 PWY-7206 pyrimidine deoxyribonucleotides dephosphorylation TPANIC_0888 PWY-5523 5,6-dimethylbenzimidazole biosynthesis TPANIC_0888 PWY-6167 flavin biosynthesis II (archaea) TPANIC_0888 PWY-6168 flavin biosynthesis III (fungi) TPANIC_0903 PWY-6386 UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) TPANIC_0903 PWY-6387 UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) TPANIC_0908 PWY-6829 tRNA methylation (yeast) TPANIC_0908 PWY-7285 methylwyosine biosynthesis TPANIC_0908 PWY-7286 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis TPANIC_0945 PWY-1861 formaldehyde assimilation II (RuMP Cycle) TPANIC_0945 PWY-5723 Rubisco shunt TPANIC_0977 PWY-5663 tetrahydrobiopterin biosynthesis I TPANIC_0977 PWY-5664 tetrahydrobiopterin biosynthesis II TPANIC_0977 PWY-6147 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I TPANIC_0977 PWY-6703 preQ0 biosynthesis TPANIC_0977 PWY-6983 tetrahydrobiopterin biosynthesis III TPANIC_0977 PWY-7442 drosopterin and aurodrosopterin biosynthesis TPANIC_1007 PWY-6545 pyrimidine deoxyribonucleotides de novo biosynthesis III TPANIC_1008 PWY-6545 pyrimidine deoxyribonucleotides de novo biosynthesis III TPANIC_1008 PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I TPANIC_1008 PWY-7198 pyrimidine deoxyribonucleotides de novo biosynthesis IV TPANIC_1008 PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP TPANIC_1008 PWY-7220 adenosine deoxyribonucleotides de novo biosynthesis II TPANIC_1008 PWY-7222 guanosine deoxyribonucleotides de novo biosynthesis II TPANIC_1008 PWY-7226 guanosine deoxyribonucleotides de novo biosynthesis I TPANIC_1008 PWY-7227 adenosine deoxyribonucleotides de novo biosynthesis TPANIC_1009 PWY-5667 CDP-diacylglycerol biosynthesis I TPANIC_1009 PWY-5981 CDP-diacylglycerol biosynthesis III TPANIC_1010 PWY-6545 pyrimidine deoxyribonucleotides de novo biosynthesis III TPANIC_1010 PWY-7176 UTP and CTP de novo biosynthesis TPANIC_1010 PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I TPANIC_1010 PWY-7187 pyrimidine deoxyribonucleotides de novo biosynthesis II TPANIC_1010 PWY-7197 pyrimidine deoxyribonucleotide phosphorylation TPANIC_1010 PWY-7198 pyrimidine deoxyribonucleotides de novo biosynthesis IV TPANIC_1010 PWY-7205 CMP phosphorylation TPANIC_1010 PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP TPANIC_1010 PWY-7220 adenosine deoxyribonucleotides de novo biosynthesis II TPANIC_1010 PWY-7221 guanosine ribonucleotides de novo biosynthesis TPANIC_1010 PWY-7222 guanosine deoxyribonucleotides de novo biosynthesis II TPANIC_1010 PWY-7224 purine deoxyribonucleosides salvage TPANIC_1010 PWY-7226 guanosine deoxyribonucleotides de novo biosynthesis I TPANIC_1010 PWY-7227 adenosine deoxyribonucleotides de novo biosynthesis TPANIC_1020 PWY-5921 glutaminyl-tRNAgln biosynthesis via transamidation TPANIC_1027 PWY-4202 arsenate detoxification I (glutaredoxin) TPANIC_1027 PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation TPANIC_1027 PWY-6608 guanosine nucleotides degradation III TPANIC_1027 PWY-6609 adenine and adenosine salvage III TPANIC_1027 PWY-6611 adenine and adenosine salvage V TPANIC_1027 PWY-6620 guanine and guanosine salvage TPANIC_1027 PWY-6627 salinosporamide A biosynthesis TPANIC_1027 PWY-6644 fluoroacetate and fluorothreonine biosynthesis TPANIC_1027 PWY-7179 purine deoxyribonucleosides degradation I TPANIC_1027 PWY-7179-1 purine deoxyribonucleosides degradation TPANIC_1039 PWY-6605 adenine and adenosine salvage II TPANIC_1039 PWY-6610 adenine and adenosine salvage IV