locus-tag	class	description
AM1_RS00070	COG0616	signal peptide processing
AM1_RS00075	COG0697	spore germination
AM1_RS00080	COG2233	PERMEase
AM1_RS00110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AM1_RS00130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM1_RS00130	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AM1_RS00145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM1_RS00155	COG2197	response regulator
AM1_RS00170	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AM1_RS00175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM1_RS00185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM1_RS00200	COG3659	wide pore channel activity
AM1_RS00210	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS00220	COG0802	atpase or kinase
AM1_RS00230	COG2203	Gaf domain
AM1_RS00230	COG0840	transmembrane signaling receptor activity
AM1_RS00235	COG0702	epimerase
AM1_RS00305	COG3328	transposase activity
AM1_RS00320	COG1217	gtp-binding protein TYPA
AM1_RS00325	COG0784	Response regulator, receiver
AM1_RS00325	COG2205	protein histidine kinase activity
AM1_RS00330	COG3706	GGDEF domain
AM1_RS00330	COG2203	Gaf domain
AM1_RS00330	COG4251	negative regulation of phosphorylation
AM1_RS00330	COG5001	Diguanylate cyclase
AM1_RS00335	COG0432	Pfam Uncharacterised protein family UPF0047
AM1_RS00340	COG1840	ABC-type Fe3 transport system, periplasmic component
AM1_RS00350	COG1196	nuclear chromosome segregation
AM1_RS00350	COG3264	Mechanosensitive ion channel
AM1_RS00370	COG0598	Magnesium transport protein CorA
AM1_RS00390	COG0457	Tetratricopeptide repeat
AM1_RS00390	COG0705	Rhomboid family
AM1_RS00400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM1_RS00455	COG3328	transposase activity
AM1_RS00485	COG3536	Protein conserved in bacteria
AM1_RS00490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM1_RS00500	COG0315	cyclic pyranopterin monophosphate synthase activity
AM1_RS00525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM1_RS00535	COG1595	DNA-templated transcription, initiation
AM1_RS00560	COG5433	transposase activity
AM1_RS00580	COG0513	Belongs to the DEAD box helicase family
AM1_RS00585	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM1_RS00590	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM1_RS00595	COG1260	myo-inositol-1-phosphate synthase
AM1_RS00605	COG1131	(ABC) transporter
AM1_RS00615	COG0837	glucose binding
AM1_RS00625	COG0366	Alpha amylase catalytic
AM1_RS00645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM1_RS00655	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AM1_RS00675	COG0436	Aminotransferase
AM1_RS00680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM1_RS00695	COG4638	Rieske (2fe-2S)
AM1_RS00710	COG0025	NhaP-type Na H and K H
AM1_RS00725	COG3903	Transcriptional regulator
AM1_RS00725	COG2319	Wd-40 repeat
AM1_RS00735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM1_RS00740	COG0848	biopolymer transport protein
AM1_RS00750	COG0811	peptide transport
AM1_RS00755	COG2319	Wd-40 repeat
AM1_RS00755	COG3903	Transcriptional regulator
AM1_RS00765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM1_RS00770	COG0581	inorganic phosphate transmembrane transporter activity
AM1_RS00775	COG0573	inorganic phosphate transmembrane transporter activity
AM1_RS00780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM1_RS00795	COG1943	Transposase
AM1_RS00805	COG1366	Belongs to the anti-sigma-factor antagonist family
AM1_RS00830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM1_RS00890	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS00905	COG0300	oxidoreductase activity
AM1_RS00915	COG1017	nitric oxide dioxygenase activity
AM1_RS00915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM1_RS00935	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM1_RS00945	COG2205	protein histidine kinase activity
AM1_RS00945	COG0784	Response regulator, receiver
AM1_RS00945	COG5002	protein histidine kinase activity
AM1_RS00965	COG0745	RESPONSE REGULATOR receiver
AM1_RS00965	COG2205	protein histidine kinase activity
AM1_RS00965	COG4191	Histidine kinase
AM1_RS00980	COG1716	ATPase activity
AM1_RS00980	COG5001	Diguanylate cyclase
AM1_RS01060	COG0582	viral genome integration into host DNA
AM1_RS01075	COG3608	succinylglutamate desuccinylase aspartoacylase
AM1_RS01075	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM1_RS01100	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AM1_RS01140	COG1222	aaa ATPase
AM1_RS01160	COG2197	response regulator
AM1_RS01165	COG4191	Histidine kinase
AM1_RS01225	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM1_RS01230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM1_RS01240	COG0784	Response regulator, receiver
AM1_RS01365	COG0072	phenylalanine-tRNA ligase activity
AM1_RS01365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM1_RS01380	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AM1_RS01415	COG1515	deoxyribonuclease V activity
AM1_RS01435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM1_RS01455	COG0672	)-iron permease
AM1_RS01515	COG0175	sulfate reduction
AM1_RS01550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM1_RS01565	COG0534	Mate efflux family protein
AM1_RS01575	COG2066	Belongs to the glutaminase family
AM1_RS01625	COG0438	transferase activity, transferring glycosyl groups
AM1_RS01640	COG0438	transferase activity, transferring glycosyl groups
AM1_RS01670	COG1132	(ABC) transporter
AM1_RS01675	COG0297	glycogen (starch) synthase activity
AM1_RS01700	COG0745	RESPONSE REGULATOR receiver
AM1_RS01705	COG5002	protein histidine kinase activity
AM1_RS01730	COG1960	acyl-CoA dehydrogenase activity
AM1_RS01735	COG0542	response to heat
AM1_RS01745	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM1_RS01755	COG0529	Catalyzes the synthesis of activated sulfate
AM1_RS01765	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AM1_RS01770	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM1_RS01780	COG0019	diaminopimelate decarboxylase activity
AM1_RS01785	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AM1_RS01790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM1_RS01805	COG1459	type II secretion system
AM1_RS01815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM1_RS01820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM1_RS01825	COG0443	Heat shock 70 kDa protein
AM1_RS01830	COG0484	heat shock protein binding
AM1_RS01840	COG1162	GTPase activity
AM1_RS01860	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM1_RS01865	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM1_RS01905	COG1882	Formate acetyltransferase
AM1_RS01910	COG0574	Belongs to the PEP-utilizing enzyme family
AM1_RS01910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM1_RS01915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM1_RS01920	COG1454	alcohol dehydrogenase
AM1_RS01920	COG1012	belongs to the aldehyde dehydrogenase family
AM1_RS01925	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AM1_RS01935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM1_RS01955	COG0723	plastoquinol--plastocyanin reductase activity
AM1_RS01965	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM1_RS01970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM1_RS02020	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AM1_RS02025	COG5398	heme oxygenase
AM1_RS02030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM1_RS02040	COG0784	Response regulator, receiver
AM1_RS02040	COG2198	Histidine kinase
AM1_RS02040	COG2205	protein histidine kinase activity
AM1_RS02055	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM1_RS02090	COG2346	COG2346, Truncated hemoglobins
AM1_RS02105	COG3335	DDE superfamily endonuclease
AM1_RS02165	COG1484	DNA-dependent DNA replication
AM1_RS02170	COG4584	PFAM Integrase catalytic
AM1_RS02235	COG2197	response regulator
AM1_RS02240	COG4585	Histidine kinase
AM1_RS02245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM1_RS02275	COG0657	acetylesterase activity
AM1_RS02280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM1_RS02285	COG1191	sigma factor activity
AM1_RS02300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM1_RS02315	COG4372	Transposase
AM1_RS02320	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AM1_RS02320	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AM1_RS02390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM1_RS02420	COG1192	Involved in chromosome partitioning
AM1_RS02425	COG0583	DNA-binding transcription factor activity
AM1_RS02440	COG0501	Belongs to the peptidase M48B family
AM1_RS02450	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM1_RS02460	COG2203	Gaf domain
AM1_RS02460	COG5001	Diguanylate cyclase
AM1_RS02460	COG4251	negative regulation of phosphorylation
AM1_RS02460	COG3706	GGDEF domain
AM1_RS02475	COG0724	RNA recognition motif
AM1_RS02505	COG0110	maltose O-acetyltransferase activity
AM1_RS02510	COG0438	transferase activity, transferring glycosyl groups
AM1_RS02530	COG5001	Diguanylate cyclase
AM1_RS02535	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM1_RS02540	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM1_RS02550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM1_RS02555	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AM1_RS02565	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM1_RS02575	COG0483	inositol monophosphate 1-phosphatase activity
AM1_RS02585	COG3273	potassium ion transport
AM1_RS02585	COG0471	metal ion transport
AM1_RS02590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM1_RS02595	COG0798	PFAM Bile acid sodium symporter
AM1_RS02600	COG0789	Transcriptional regulator
AM1_RS02610	COG0751	glycine-tRNA ligase activity
AM1_RS02615	COG0612	Peptidase, M16
AM1_RS02625	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM1_RS02630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM1_RS02635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM1_RS02640	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM1_RS02650	COG2124	cytochrome p450
AM1_RS02660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM1_RS02660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM1_RS02665	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM1_RS02695	COG0408	coproporphyrinogen oxidase activity
AM1_RS02705	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AM1_RS02715	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AM1_RS02720	COG0501	Belongs to the peptidase M48B family
AM1_RS02740	COG0739	heme binding
AM1_RS02745	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AM1_RS02745	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AM1_RS02750	COG1496	oxidoreductase activity
AM1_RS02780	COG0583	DNA-binding transcription factor activity
AM1_RS02785	COG1741	Belongs to the pirin family
AM1_RS02795	COG0784	Response regulator, receiver
AM1_RS02795	COG2205	protein histidine kinase activity
AM1_RS02800	COG0589	response to stress
AM1_RS02805	COG0126	phosphoglycerate kinase activity
AM1_RS02830	COG0124	histidyl-tRNA synthetase
AM1_RS02850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM1_RS02855	COG0577	efflux transmembrane transporter activity
AM1_RS02855	COG1136	(ABC) transporter
AM1_RS02860	COG1136	(ABC) transporter
AM1_RS02880	COG0416	fatty acid biosynthetic process
AM1_RS02885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM1_RS02890	COG0697	spore germination
AM1_RS02895	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM1_RS02900	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM1_RS02905	COG0517	IMP dehydrogenase activity
AM1_RS02905	COG1125	glycine betaine transport
AM1_RS02920	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AM1_RS02930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM1_RS02945	COG0484	heat shock protein binding
AM1_RS02950	COG1994	Peptidase M50
AM1_RS02965	COG0390	transport system, permease component
AM1_RS02970	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AM1_RS03010	COG1662	PFAM IS1 transposase
AM1_RS03020	COG1487	ribonuclease activity
AM1_RS03055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM1_RS03060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM1_RS03065	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM1_RS03065	COG0022	dehydrogenase e1 component
AM1_RS03080	COG2226	methyltransferase
AM1_RS03090	COG0515	serine threonine protein kinase
AM1_RS03110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM1_RS03130	COG3328	transposase activity
AM1_RS03145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM1_RS03150	COG4251	negative regulation of phosphorylation
AM1_RS03150	COG5001	Diguanylate cyclase
AM1_RS03150	COG3706	GGDEF domain
AM1_RS03150	COG2203	Gaf domain
AM1_RS03160	COG1672	PFAM Archaeal ATPase
AM1_RS03160	COG2319	Wd-40 repeat
AM1_RS03175	COG0318	PFAM AMP-dependent synthetase and ligase
AM1_RS03200	COG4221	oxidoreductase activity
AM1_RS03200	COG3321	synthase
AM1_RS03200	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS03200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM1_RS03205	COG0156	8-amino-7-oxononanoate synthase activity
AM1_RS03215	COG4221	oxidoreductase activity
AM1_RS03270	COG1662	PFAM IS1 transposase
AM1_RS03280	COG0587	DNA-directed DNA polymerase activity
AM1_RS03290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM1_RS03295	COG0814	amino acid
AM1_RS03400	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AM1_RS03415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM1_RS03420	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM1_RS03435	COG2363	Small membrane protein
AM1_RS03445	COG1361	Conserved repeat domain
AM1_RS03465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM1_RS03475	COG1515	deoxyribonuclease V activity
AM1_RS03510	COG1615	UPF0182 protein
AM1_RS03520	COG0646	methionine synthase
AM1_RS03520	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM1_RS03550	COG0431	NADPH-dependent FMN reductase
AM1_RS03565	COG0438	transferase activity, transferring glycosyl groups
AM1_RS03585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM1_RS03590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM1_RS03600	COG1122	ATPase activity
AM1_RS03605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM1_RS03630	COG0753	catalase activity
AM1_RS03645	COG1309	transcriptional regulator
AM1_RS03655	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM1_RS03665	COG2124	cytochrome p450
AM1_RS03680	COG0745	RESPONSE REGULATOR receiver
AM1_RS03690	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM1_RS03695	COG1672	PFAM Archaeal ATPase
AM1_RS03695	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AM1_RS03710	COG1233	COG1233 Phytoene dehydrogenase and related
AM1_RS03735	COG0612	Peptidase, M16
AM1_RS03745	COG3011	Protein conserved in bacteria
AM1_RS03765	COG0768	penicillin binding
AM1_RS03775	COG0275	rRNA processing
AM1_RS03780	COG5398	heme oxygenase
AM1_RS03795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM1_RS03805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM1_RS03810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM1_RS03845	COG3659	wide pore channel activity
AM1_RS03850	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM1_RS03855	COG0830	nickel cation binding
AM1_RS03885	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AM1_RS03890	COG0175	sulfate reduction
AM1_RS03925	COG2226	methyltransferase
AM1_RS03955	COG0356	it plays a direct role in the translocation of protons across the membrane
AM1_RS03965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM1_RS03970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM1_RS03975	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM1_RS03980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM1_RS03985	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM1_RS03990	COG0473	3-isopropylmalate dehydrogenase activity
AM1_RS03995	COG4636	protein conserved in cyanobacteria
AM1_RS04020	COG0066	3-isopropylmalate dehydratase activity
AM1_RS04030	COG0784	Response regulator, receiver
AM1_RS04045	COG0840	transmembrane signaling receptor activity
AM1_RS04045	COG2203	Gaf domain
AM1_RS04050	COG0643	Histidine kinase
AM1_RS04050	COG2198	Histidine kinase
AM1_RS04050	COG0784	Response regulator, receiver
AM1_RS04065	COG0004	ammonium transporteR
AM1_RS04075	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM1_RS04080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM1_RS04095	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AM1_RS04100	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AM1_RS04115	COG0779	Required for maturation of 30S ribosomal subunits
AM1_RS04120	COG0195	Participates in both transcription termination and antitermination
AM1_RS04125	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM1_RS04160	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM1_RS04175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM1_RS04180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM1_RS04205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM1_RS04210	COG0469	pyruvate kinase activity
AM1_RS04215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM1_RS04230	COG2217	Heavy metal translocating P-type atpase
AM1_RS04245	COG2831	hemolysin activation secretion protein
AM1_RS04250	COG2205	protein histidine kinase activity
AM1_RS04270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM1_RS04310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM1_RS04325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM1_RS04330	COG1136	(ABC) transporter
AM1_RS04360	COG0564	pseudouridine synthase activity
AM1_RS04385	COG1136	(ABC) transporter
AM1_RS04410	COG0457	Tetratricopeptide repeat
AM1_RS04410	COG0463	Glycosyl transferase, family 2
AM1_RS04415	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AM1_RS04420	COG4251	negative regulation of phosphorylation
AM1_RS04435	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AM1_RS04460	COG1045	serine acetyltransferase
AM1_RS04480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AM1_RS04490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM1_RS04500	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AM1_RS04500	COG0617	tRNA 3'-terminal CCA addition
AM1_RS04500	COG0517	IMP dehydrogenase activity
AM1_RS04505	COG4597	amino acid ABC transporter
AM1_RS04510	COG0765	amino acid transport
AM1_RS04515	COG1126	abc transporter atp-binding protein
AM1_RS04525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM1_RS04545	COG0438	transferase activity, transferring glycosyl groups
AM1_RS04550	COG0438	transferase activity, transferring glycosyl groups
AM1_RS04605	COG0495	leucyl-tRNA aminoacylation
AM1_RS04615	COG3657	addiction module killer protein
AM1_RS04620	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM1_RS04665	COG0583	DNA-binding transcription factor activity
AM1_RS04680	COG1672	PFAM Archaeal ATPase
AM1_RS04680	COG2319	Wd-40 repeat
AM1_RS04685	COG2203	Gaf domain
AM1_RS04685	COG3706	GGDEF domain
AM1_RS04685	COG4251	negative regulation of phosphorylation
AM1_RS04685	COG5001	Diguanylate cyclase
AM1_RS04695	COG0424	maF-like protein
AM1_RS04710	COG0024	Methionine aminopeptidase
AM1_RS04720	COG1968	undecaprenyl-diphosphatase activity
AM1_RS04740	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM1_RS04745	COG1799	cell septum assembly
AM1_RS04750	COG0277	FAD linked oxidase domain protein
AM1_RS04775	COG3239	Fatty acid desaturase
AM1_RS04785	COG1054	Belongs to the UPF0176 family
AM1_RS04795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM1_RS04800	COG0456	acetyltransferase
AM1_RS04805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM1_RS04830	COG0653	protein targeting
AM1_RS04840	COG2095	MarC family integral membrane protein
AM1_RS04855	COG1446	asparaginase
AM1_RS04865	COG2226	methyltransferase
AM1_RS04870	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AM1_RS04900	COG3541	Predicted nucleotidyltransferase
AM1_RS04915	COG0840	transmembrane signaling receptor activity
AM1_RS04935	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AM1_RS04945	COG1575	Belongs to the MenA family. Type 1 subfamily
AM1_RS04950	COG0484	heat shock protein binding
AM1_RS04955	COG0702	epimerase
AM1_RS04960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM1_RS04970	COG0322	excinuclease ABC activity
AM1_RS04980	COG0297	glycogen (starch) synthase activity
AM1_RS04990	COG1309	transcriptional regulator
AM1_RS05015	COG1649	PFAM Uncharacterised BCR, COG1649
AM1_RS05030	COG0735	belongs to the Fur family
AM1_RS05065	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM1_RS05070	COG1420	regulation of RNA biosynthetic process
AM1_RS05105	COG0501	Belongs to the peptidase M48B family
AM1_RS05115	COG0776	regulation of translation
AM1_RS05120	COG0575	Belongs to the CDS family
AM1_RS05130	COG0745	RESPONSE REGULATOR receiver
AM1_RS05135	COG2172	sigma factor antagonist activity
AM1_RS05140	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AM1_RS05145	COG1051	belongs to the nudix hydrolase family
AM1_RS05150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM1_RS05155	COG0456	acetyltransferase
AM1_RS05160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM1_RS05200	COG1331	Highly conserved protein containing a thioredoxin domain
AM1_RS05225	COG1671	Belongs to the UPF0178 family
AM1_RS05245	COG0625	glutathione transferase activity
AM1_RS05265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM1_RS05305	COG0523	cobalamin synthesis protein
AM1_RS05340	COG5635	Nacht domain
AM1_RS05340	COG2319	Wd-40 repeat
AM1_RS05365	COG1252	NADH dehydrogenase
AM1_RS05420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM1_RS05425	COG0719	Fe-S assembly protein
AM1_RS05430	COG0396	ATPase activity
AM1_RS05435	COG0719	Fe-S assembly protein
AM1_RS05460	COG1309	transcriptional regulator
AM1_RS05465	COG0625	glutathione transferase activity
AM1_RS05540	COG4221	oxidoreductase activity
AM1_RS05545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM1_RS05550	COG1376	ErfK ybiS ycfS ynhG family protein
AM1_RS05555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM1_RS05560	COG0254	rRNA binding
AM1_RS05565	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM1_RS05570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM1_RS05575	COG0101	tRNA pseudouridine synthase activity
AM1_RS05580	COG0203	ribosomal protein L17
AM1_RS05585	COG0202	RNA polymerase activity
AM1_RS05590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM1_RS05595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM1_RS05600	COG0646	methionine synthase
AM1_RS05600	COG1410	methionine synthase
AM1_RS05620	COG0584	glycerophosphoryl diester phosphodiesterase
AM1_RS05630	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AM1_RS05635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM1_RS05645	COG2827	Endonuclease containing a URI domain
AM1_RS05655	COG3012	SEC-C Motif Domain Protein
AM1_RS05685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM1_RS05690	COG2264	protein methyltransferase activity
AM1_RS05720	COG3266	domain, Protein
AM1_RS05720	COG2911	Protein conserved in bacteria
AM1_RS05720	COG1361	Conserved repeat domain
AM1_RS05725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM1_RS05735	COG4956	integral membrane protein (PIN domain superfamily)
AM1_RS05810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS05820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS05825	COG1803	Methylglyoxal synthase
AM1_RS05825	COG1597	lipid kinase activity
AM1_RS05865	COG2207	Transcriptional regulator
AM1_RS05890	COG0667	Aldo Keto reductase
AM1_RS05900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM1_RS05905	COG1073	alpha beta
AM1_RS05945	COG1309	transcriptional regulator
AM1_RS05950	COG1454	alcohol dehydrogenase
AM1_RS05955	COG1012	belongs to the aldehyde dehydrogenase family
AM1_RS05990	COG0159	tryptophan synthase activity
AM1_RS06005	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM1_RS06015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM1_RS06050	COG0606	chelatase, subunit chli
AM1_RS06055	COG3063	Type IV pilus biogenesis stability protein PilW
AM1_RS06060	COG4172	Belongs to the ABC transporter superfamily
AM1_RS06065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM1_RS06075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM1_RS06080	COG2045	Belongs to the ComB family
AM1_RS06100	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM1_RS06105	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AM1_RS06110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM1_RS06115	COG0339	signal peptide processing
AM1_RS06120	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS06120	COG0515	serine threonine protein kinase
AM1_RS06125	COG0840	transmembrane signaling receptor activity
AM1_RS06125	COG2203	Gaf domain
AM1_RS06130	COG0784	Response regulator, receiver
AM1_RS06130	COG2205	protein histidine kinase activity
AM1_RS06140	COG0303	'Molybdopterin
AM1_RS06150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM1_RS06150	COG0426	domain, Protein
AM1_RS06155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM1_RS06155	COG0426	domain, Protein
AM1_RS06170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM1_RS06195	COG0114	fumarate hydratase activity
AM1_RS06220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM1_RS06225	COG1196	nuclear chromosome segregation
AM1_RS06225	COG3264	Mechanosensitive ion channel
AM1_RS06235	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM1_RS06240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM1_RS06260	COG1473	amidohydrolase
AM1_RS06290	COG2308	Evidence 4 Homologs of previously reported genes of
AM1_RS06300	COG5001	Diguanylate cyclase
AM1_RS06300	COG5002	protein histidine kinase activity
AM1_RS06305	COG0709	Synthesizes selenophosphate from selenide and ATP
AM1_RS06345	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AM1_RS06350	COG2319	Wd-40 repeat
AM1_RS06350	COG3903	Transcriptional regulator
AM1_RS06355	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AM1_RS06360	COG0546	phosphoglycolate phosphatase activity
AM1_RS06375	COG0512	Glutamine amidotransferase of anthranilate synthase
AM1_RS06380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM1_RS06385	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM1_RS06395	COG0047	phosphoribosylformylglycinamidine synthase activity
AM1_RS06400	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM1_RS06405	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM1_RS06415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM1_RS06415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM1_RS06430	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM1_RS06445	COG1278	Cold shock
AM1_RS06450	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AM1_RS06455	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AM1_RS06465	COG0489	protein tyrosine kinase activity
AM1_RS06470	COG0772	Belongs to the SEDS family
AM1_RS06485	COG0539	negative regulation of cytoplasmic translation
AM1_RS06490	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AM1_RS06525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM1_RS06550	COG2205	protein histidine kinase activity
AM1_RS06610	COG0745	RESPONSE REGULATOR receiver
AM1_RS06645	COG0762	integral membrane protein
AM1_RS06650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM1_RS06665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM1_RS06680	COG0174	glutamine synthetase
AM1_RS06690	COG0784	Response regulator, receiver
AM1_RS06690	COG5002	protein histidine kinase activity
AM1_RS06715	COG2239	Acts as a magnesium transporter
AM1_RS06725	COG0191	fructose-bisphosphate aldolase activity
AM1_RS06730	COG0739	heme binding
AM1_RS06735	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM1_RS06740	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AM1_RS06760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM1_RS06805	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AM1_RS06810	COG1063	alcohol dehydrogenase
AM1_RS06820	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AM1_RS06825	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AM1_RS06835	COG0509	glycine decarboxylation via glycine cleavage system
AM1_RS06840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM1_RS06865	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AM1_RS06870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM1_RS06915	COG1733	regulation of RNA biosynthetic process
AM1_RS06935	COG0784	Response regulator, receiver
AM1_RS06935	COG2205	protein histidine kinase activity
AM1_RS06975	COG4585	Histidine kinase
AM1_RS06980	COG2197	response regulator
AM1_RS06995	COG2226	methyltransferase
AM1_RS07010	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AM1_RS07035	COG0515	serine threonine protein kinase
AM1_RS07035	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS07065	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS07065	COG0515	serine threonine protein kinase
AM1_RS07070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM1_RS07105	COG1126	abc transporter atp-binding protein
AM1_RS07110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM1_RS07130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS07135	COG1136	(ABC) transporter
AM1_RS07175	COG0625	glutathione transferase activity
AM1_RS07180	COG1733	regulation of RNA biosynthetic process
AM1_RS07225	COG0604	alcohol dehydrogenase
AM1_RS07235	COG1024	Enoyl-CoA hydratase
AM1_RS07235	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM1_RS07240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM1_RS07245	COG4221	oxidoreductase activity
AM1_RS07265	COG4251	negative regulation of phosphorylation
AM1_RS07265	COG3706	GGDEF domain
AM1_RS07265	COG2203	Gaf domain
AM1_RS07265	COG5001	Diguanylate cyclase
AM1_RS07270	COG1049	propionate catabolic process, 2-methylcitrate cycle
AM1_RS07305	COG0135	phosphoribosylanthranilate isomerase activity
AM1_RS07310	COG0745	RESPONSE REGULATOR receiver
AM1_RS07315	COG0167	dihydroorotate dehydrogenase activity
AM1_RS07330	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AM1_RS07340	COG0574	Belongs to the PEP-utilizing enzyme family
AM1_RS07340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM1_RS07345	COG0589	response to stress
AM1_RS07360	COG1305	Transglutaminase-like
AM1_RS07380	COG3854	ATPases associated with a variety of cellular activities
AM1_RS07390	COG5002	protein histidine kinase activity
AM1_RS07400	COG2072	flavoprotein involved in K transport
AM1_RS07405	COG1166	arginine decarboxylase activity
AM1_RS07415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM1_RS07425	COG0067	glutamate synthase
AM1_RS07425	COG0070	glutamate synthase
AM1_RS07425	COG0069	glutamate synthase activity
AM1_RS07445	COG0121	glutamine amidotransferase
AM1_RS07460	COG1404	Belongs to the peptidase S8 family
AM1_RS07475	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM1_RS07480	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM1_RS07510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM1_RS07515	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AM1_RS07525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM1_RS07540	COG1032	radical SAM domain protein
AM1_RS07560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM1_RS07565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM1_RS07580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM1_RS07585	COG0513	Belongs to the DEAD box helicase family
AM1_RS07590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM1_RS07595	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AM1_RS07600	COG1530	ribonuclease E activity
AM1_RS07605	COG0412	Dienelactone hydrolase
AM1_RS07610	COG1725	Transcriptional regulator
AM1_RS07615	COG2304	oxidoreductase activity
AM1_RS07630	COG0612	Peptidase, M16
AM1_RS07645	COG0571	ribonuclease III activity
AM1_RS07650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM1_RS07655	COG0484	heat shock protein binding
AM1_RS07660	COG0037	tRNA processing
AM1_RS07665	COG0745	RESPONSE REGULATOR receiver
AM1_RS07675	COG1011	Hydrolase
AM1_RS07690	COG0784	Response regulator, receiver
AM1_RS07695	COG4251	negative regulation of phosphorylation
AM1_RS07700	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM1_RS07715	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AM1_RS07725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AM1_RS07735	COG0180	Tryptophanyl-tRNA synthetase
AM1_RS07740	COG5002	protein histidine kinase activity
AM1_RS07750	COG0285	dihydrofolate synthase activity
AM1_RS07775	COG1132	(ABC) transporter
AM1_RS07780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM1_RS07785	COG2010	Cytochrome c
AM1_RS07805	COG1819	glycosyl
AM1_RS07820	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM1_RS07825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM1_RS07850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM1_RS07885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM1_RS07890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM1_RS07905	COG0243	molybdopterin cofactor binding
AM1_RS07950	COG4451	ribulose bisphosphate carboxylase, small
AM1_RS07950	COG0464	growth
AM1_RS07960	COG4451	ribulose bisphosphate carboxylase, small
AM1_RS07970	COG1850	ribulose-bisphosphate carboxylase activity
AM1_RS07975	COG0454	-acetyltransferase
AM1_RS07990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM1_RS08010	COG0051	transcription antitermination factor activity, RNA binding
AM1_RS08015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM1_RS08020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM1_RS08025	COG0049	tRNA binding
AM1_RS08030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM1_RS08035	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AM1_RS08040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM1_RS08045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM1_RS08050	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM1_RS08065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM1_RS08070	COG0745	RESPONSE REGULATOR receiver
AM1_RS08080	COG1333	cytochrome c biogenesis protein
AM1_RS08090	COG0772	Belongs to the SEDS family
AM1_RS08105	COG3659	wide pore channel activity
AM1_RS08125	COG1136	(ABC) transporter
AM1_RS08170	COG0659	secondary active sulfate transmembrane transporter activity
AM1_RS08175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS08180	COG2217	Heavy metal translocating P-type atpase
AM1_RS08200	COG2321	neutral zinc metallopeptidase
AM1_RS08230	COG2203	Gaf domain
AM1_RS08230	COG3706	GGDEF domain
AM1_RS08230	COG4251	negative regulation of phosphorylation
AM1_RS08230	COG5001	Diguanylate cyclase
AM1_RS08250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM1_RS08255	COG0217	transcriptional regulatory protein
AM1_RS08265	COG2884	Cell division ATP-binding protein ftsE
AM1_RS08270	COG2177	Part of the ABC transporter FtsEX involved in
AM1_RS08290	COG2815	serine threonine protein kinase
AM1_RS08290	COG0515	serine threonine protein kinase
AM1_RS08325	COG1666	GTP binding
AM1_RS08330	COG1012	belongs to the aldehyde dehydrogenase family
AM1_RS08345	COG0516	GMP reductase activity
AM1_RS08350	COG3118	belongs to the thioredoxin family
AM1_RS08360	COG0784	Response regulator, receiver
AM1_RS08360	COG5002	protein histidine kinase activity
AM1_RS08360	COG2205	protein histidine kinase activity
AM1_RS08380	COG0693	protein deglycase activity
AM1_RS08390	COG0737	Belongs to the 5'-nucleotidase family
AM1_RS08400	COG0436	Aminotransferase
AM1_RS08415	COG0540	Belongs to the ATCase OTCase family
AM1_RS08425	COG1122	ATPase activity
AM1_RS08440	COG3594	Acyltransferase
AM1_RS08450	COG2226	methyltransferase
AM1_RS08460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM1_RS08465	COG0438	transferase activity, transferring glycosyl groups
AM1_RS08485	COG2226	methyltransferase
AM1_RS08510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM1_RS08520	COG2244	polysaccharide biosynthetic process
AM1_RS08525	COG0489	protein tyrosine kinase activity
AM1_RS08525	COG3206	protein involved in exopolysaccharide biosynthesis
AM1_RS08530	COG0438	transferase activity, transferring glycosyl groups
AM1_RS08545	COG2850	peptidyl-arginine hydroxylation
AM1_RS08550	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AM1_RS08575	COG1473	amidohydrolase
AM1_RS08610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM1_RS08615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM1_RS08630	COG0360	Binds together with S18 to 16S ribosomal RNA
AM1_RS08635	COG2199	diguanylate cyclase activity
AM1_RS08635	COG3287	FIST C domain
AM1_RS08635	COG2200	EAL domain
AM1_RS08655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AM1_RS08660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM1_RS08665	COG1546	Belongs to the CinA family
AM1_RS08665	COG1058	Belongs to the CinA family
AM1_RS08675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM1_RS08680	COG0488	(ABC) transporter
AM1_RS08690	COG0456	acetyltransferase
AM1_RS08695	COG0542	response to heat
AM1_RS08710	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM1_RS08730	COG0037	tRNA processing
AM1_RS08750	COG0352	thiamine-phosphate diphosphorylase activity
AM1_RS08760	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM1_RS08775	COG1858	cytochrome C peroxidase
AM1_RS08780	COG0784	Response regulator, receiver
AM1_RS08780	COG5002	protein histidine kinase activity
AM1_RS08805	COG0434	BtpA family
AM1_RS08810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM1_RS08815	COG0494	nUDIX hydrolase
AM1_RS08820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM1_RS08840	COG3596	GTP binding
AM1_RS08875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM1_RS08880	COG0501	Belongs to the peptidase M48B family
AM1_RS08920	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AM1_RS08995	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AM1_RS09000	COG1819	glycosyl
AM1_RS09015	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AM1_RS09030	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM1_RS09040	COG0668	transmembrane transport
AM1_RS09045	COG0017	Asparaginyl-tRNA synthetase
AM1_RS09055	COG0297	glycogen (starch) synthase activity
AM1_RS09060	COG0724	RNA recognition motif
AM1_RS09075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM1_RS09080	COG3977	Valine--pyruvate aminotransferase
AM1_RS09110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM1_RS09145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM1_RS09150	COG1007	ATP synthesis coupled electron transport
AM1_RS09160	COG0644	oxidoreductase
AM1_RS09170	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM1_RS09175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM1_RS09185	COG0742	ribosomal rna small subunit methyltransferase
AM1_RS09210	COG0443	Heat shock 70 kDa protein
AM1_RS09225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM1_RS09230	COG0460	homoserine dehydrogenase
AM1_RS09255	COG0456	acetyltransferase
AM1_RS09265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM1_RS09270	COG0616	signal peptide processing
AM1_RS09280	COG2207	Transcriptional regulator
AM1_RS09300	COG0702	epimerase
AM1_RS09310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM1_RS09320	COG0747	negative chemotaxis
AM1_RS09330	COG0793	Belongs to the peptidase S41A family
AM1_RS09340	COG1858	cytochrome C peroxidase
AM1_RS09350	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM1_RS09360	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM1_RS09425	COG1640	4-alpha-glucanotransferase
AM1_RS09430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM1_RS09450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS09455	COG0735	belongs to the Fur family
AM1_RS09470	COG0572	uridine kinase
AM1_RS09475	COG0058	SHG alpha-glucan phosphorylase activity
AM1_RS09480	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM1_RS09490	COG2267	carboxylic ester hydrolase activity
AM1_RS09495	COG0440	acetolactate synthase activity
AM1_RS09510	COG0439	Biotin carboxylase
AM1_RS09520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM1_RS09525	COG0542	response to heat
AM1_RS09535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM1_RS09550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS09565	COG0475	glutathione-regulated potassium exporter activity
AM1_RS09575	COG0039	L-malate dehydrogenase activity
AM1_RS09605	COG2267	carboxylic ester hydrolase activity
AM1_RS09620	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM1_RS09620	COG1024	Enoyl-CoA hydratase
AM1_RS09625	COG0183	Belongs to the thiolase family
AM1_RS09630	COG1960	acyl-CoA dehydrogenase activity
AM1_RS09635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM1_RS09635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM1_RS09660	COG2062	phosphohistidine phosphatase, SixA
AM1_RS09665	COG0372	Belongs to the citrate synthase family
AM1_RS09670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AM1_RS09675	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM1_RS09695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM1_RS09725	COG0537	adenosine 5'-monophosphoramidase activity
AM1_RS09735	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM1_RS09740	COG0629	single-stranded DNA binding
AM1_RS09745	COG0151	Belongs to the GarS family
AM1_RS09775	COG1131	(ABC) transporter
AM1_RS09775	COG1716	ATPase activity
AM1_RS09775	COG0842	Transport permease protein
AM1_RS09780	COG0515	serine threonine protein kinase
AM1_RS09780	COG2815	serine threonine protein kinase
AM1_RS09785	COG1253	flavin adenine dinucleotide binding
AM1_RS09790	COG1178	ABC-type Fe3 transport system permease component
AM1_RS09795	COG0445	tRNA wobble uridine modification
AM1_RS09820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM1_RS09825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM1_RS09845	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM1_RS09845	COG0517	IMP dehydrogenase activity
AM1_RS09850	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AM1_RS09855	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AM1_RS09860	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM1_RS09960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM1_RS09970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM1_RS09985	COG2072	flavoprotein involved in K transport
AM1_RS10010	COG2144	transferase activity, transferring acyl groups
AM1_RS10045	COG0438	transferase activity, transferring glycosyl groups
AM1_RS10055	COG2197	response regulator
AM1_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS10105	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM1_RS10120	COG0625	glutathione transferase activity
AM1_RS10145	COG0583	DNA-binding transcription factor activity
AM1_RS10160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM1_RS10250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM1_RS10255	COG1494	fructose-1,6-bisphosphatase
AM1_RS10265	COG1662	PFAM IS1 transposase
AM1_RS10280	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM1_RS10280	COG0456	acetyltransferase
AM1_RS10290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM1_RS10300	COG0515	serine threonine protein kinase
AM1_RS10300	COG3266	domain, Protein
AM1_RS10305	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AM1_RS10310	COG0156	8-amino-7-oxononanoate synthase activity
AM1_RS10325	COG4172	Belongs to the ABC transporter superfamily
AM1_RS10335	COG0728	peptidoglycan biosynthetic process
AM1_RS10340	COG0728	peptidoglycan biosynthetic process
AM1_RS10355	COG4221	oxidoreductase activity
AM1_RS10360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM1_RS10370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM1_RS10395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM1_RS10415	COG1127	ABC transporter
AM1_RS10430	COG0442	prolyl-tRNA aminoacylation
AM1_RS10450	COG0387	Pfam Sodium calcium exchanger
AM1_RS10475	COG0740	serine-type endopeptidase activity
AM1_RS10480	COG0740	serine-type endopeptidase activity
AM1_RS10505	COG1846	Transcriptional regulator
AM1_RS10505	COG0456	acetyltransferase
AM1_RS10510	COG0564	pseudouridine synthase activity
AM1_RS10515	COG0613	PHP domain protein
AM1_RS10525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS10530	COG1489	DNA binding
AM1_RS10540	COG0602	queuosine metabolic process
AM1_RS10545	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM1_RS10555	COG1040	competence protein
AM1_RS10560	COG0574	Belongs to the PEP-utilizing enzyme family
AM1_RS10560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM1_RS10570	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM1_RS10585	COG0739	heme binding
AM1_RS10595	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AM1_RS10610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM1_RS10615	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM1_RS10630	COG0714	Associated with various cellular activities
AM1_RS10650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM1_RS10655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AM1_RS10660	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AM1_RS10690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM1_RS10695	COG0631	protein serine/threonine phosphatase activity
AM1_RS10700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM1_RS10725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM1_RS10750	COG1716	ATPase activity
AM1_RS10750	COG5001	Diguanylate cyclase
AM1_RS10760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM1_RS10820	COG2176	DNA-directed DNA polymerase activity
AM1_RS10845	COG5433	transposase activity
AM1_RS10870	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM1_RS10875	COG0563	adenylate kinase activity
AM1_RS10880	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AM1_RS10890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM1_RS10900	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AM1_RS10915	COG2154	pterin-4-alpha-carbinolamine dehydratase
AM1_RS10920	COG0357	Ribosomal RNA small subunit methyltransferase G
AM1_RS10925	COG3128	pkhd-type hydroxylase
AM1_RS10935	COG0415	Belongs to the DNA photolyase family
AM1_RS10950	COG3693	PFAM glycoside hydrolase, family 10
AM1_RS10970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS10985	COG0443	Heat shock 70 kDa protein
AM1_RS11005	COG0351	phosphomethylpyrimidine kinase
AM1_RS11060	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM1_RS11070	COG2885	chlorophyll binding
AM1_RS11075	COG2885	chlorophyll binding
AM1_RS11090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM1_RS11100	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AM1_RS11105	COG0842	Transport permease protein
AM1_RS11105	COG1131	(ABC) transporter
AM1_RS11105	COG1716	ATPase activity
AM1_RS11110	COG0312	modulator of DNA gyrase
AM1_RS11115	COG0312	modulator of DNA gyrase
AM1_RS11120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM1_RS11125	COG0438	transferase activity, transferring glycosyl groups
AM1_RS11190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM1_RS11225	COG3001	Fructosamine kinase
AM1_RS11240	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM1_RS11255	COG3118	belongs to the thioredoxin family
AM1_RS11260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM1_RS11265	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM1_RS11285	COG0714	Associated with various cellular activities
AM1_RS11290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AM1_RS11300	COG2205	protein histidine kinase activity
AM1_RS11305	COG2319	Wd-40 repeat
AM1_RS11305	COG1672	PFAM Archaeal ATPase
AM1_RS11310	COG0515	serine threonine protein kinase
AM1_RS11340	COG0587	DNA-directed DNA polymerase activity
AM1_RS11345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM1_RS11350	COG4245	von Willebrand factor, type A
AM1_RS11375	COG0705	Rhomboid family
AM1_RS11400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM1_RS11410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM1_RS11425	COG0667	Aldo Keto reductase
AM1_RS11440	COG0464	growth
AM1_RS11450	COG2020	methyltransferase activity
AM1_RS11475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM1_RS11480	COG1695	Transcriptional regulator
AM1_RS11520	COG0431	NADPH-dependent FMN reductase
AM1_RS11530	COG0475	glutathione-regulated potassium exporter activity
AM1_RS11530	COG0589	response to stress
AM1_RS11535	COG1716	ATPase activity
AM1_RS11545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM1_RS11545	COG0140	phosphoribosyl-ATP diphosphatase activity
AM1_RS11560	COG3118	belongs to the thioredoxin family
AM1_RS11565	COG0358	DNA primase activity
AM1_RS11585	COG1902	pentaerythritol trinitrate reductase activity
AM1_RS11590	COG2010	Cytochrome c
AM1_RS11600	COG1858	cytochrome C peroxidase
AM1_RS11610	COG1566	PFAM secretion protein HlyD family protein
AM1_RS11620	COG1136	(ABC) transporter
AM1_RS11620	COG0577	efflux transmembrane transporter activity
AM1_RS11650	COG1595	DNA-templated transcription, initiation
AM1_RS11665	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM1_RS11725	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM1_RS11730	COG1509	lysine 2,3-aminomutase activity
AM1_RS11735	COG2720	vancomycin resistance protein
AM1_RS11770	COG4115	mRNA cleavage
AM1_RS11800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM1_RS11805	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM1_RS11815	COG0525	valine-tRNA ligase activity
AM1_RS11820	COG0724	RNA recognition motif
AM1_RS11825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM1_RS11830	COG1047	Peptidyl-prolyl cis-trans
AM1_RS11845	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM1_RS11845	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM1_RS11850	COG0436	Aminotransferase
AM1_RS11875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM1_RS11890	COG4447	cellulose binding
AM1_RS11895	COG1773	rubredoxin
AM1_RS11900	COG0012	GTP binding
AM1_RS11905	COG1982	Orn Lys Arg decarboxylase major
AM1_RS11920	COG0363	glucosamine-6-phosphate deaminase activity
AM1_RS11925	COG1716	ATPase activity
AM1_RS11930	COG0515	serine threonine protein kinase
AM1_RS11935	COG1073	alpha beta
AM1_RS11955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM1_RS11980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM1_RS11980	COG4651	solute:proton antiporter activity
AM1_RS11985	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM1_RS11990	COG1234	tRNA 3'-trailer cleavage
AM1_RS11995	COG0196	riboflavin kinase activity
AM1_RS12000	COG0714	Associated with various cellular activities
AM1_RS12010	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AM1_RS12035	COG1104	cysteine desulfurase activity
AM1_RS12135	COG0741	lytic transglycosylase activity
AM1_RS12135	COG0739	heme binding
AM1_RS12135	COG1196	nuclear chromosome segregation
AM1_RS12150	COG5001	Diguanylate cyclase
AM1_RS12150	COG1716	ATPase activity
AM1_RS12155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM1_RS12165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM1_RS12185	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM1_RS12195	COG1252	NADH dehydrogenase
AM1_RS12200	COG0450	alkyl hydroperoxide reductase
AM1_RS12205	COG0463	Glycosyl transferase, family 2
AM1_RS12220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM1_RS12235	COG2226	methyltransferase
AM1_RS12285	COG0726	polysaccharide deacetylase
AM1_RS12305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM1_RS12310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AM1_RS12320	COG0640	Transcriptional regulator
AM1_RS12335	COG2852	Protein conserved in bacteria
AM1_RS12350	COG2197	response regulator
AM1_RS12360	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AM1_RS12370	COG0393	Putative heavy-metal-binding
AM1_RS12410	COG0247	lactate metabolic process
AM1_RS12415	COG0277	FAD linked oxidase domain protein
AM1_RS12430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM1_RS12445	COG4115	mRNA cleavage
AM1_RS12480	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM1_RS12515	COG0497	DNA recombination
AM1_RS12535	COG0237	dephospho-CoA kinase activity
AM1_RS12605	COG1053	succinate dehydrogenase
AM1_RS12620	COG1309	transcriptional regulator
AM1_RS12625	COG3152	Membrane
AM1_RS12635	COG2267	carboxylic ester hydrolase activity
AM1_RS12640	COG2723	6-phospho-beta-galactosidase activity
AM1_RS12645	COG0515	serine threonine protein kinase
AM1_RS12645	COG3266	domain, Protein
AM1_RS12670	COG2954	triphosphatase activity
AM1_RS12680	COG5002	protein histidine kinase activity
AM1_RS12685	COG1981	membrane
AM1_RS12690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM1_RS12705	COG1196	nuclear chromosome segregation
AM1_RS12715	COG0489	protein tyrosine kinase activity
AM1_RS12725	COG0489	protein tyrosine kinase activity
AM1_RS12725	COG3206	protein involved in exopolysaccharide biosynthesis
AM1_RS12745	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AM1_RS12750	COG3250	beta-galactosidase activity
AM1_RS12755	COG3291	Pkd domain containing protein
AM1_RS12775	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS12775	COG0515	serine threonine protein kinase
AM1_RS12780	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS12780	COG0515	serine threonine protein kinase
AM1_RS12805	COG0457	Tetratricopeptide repeat
AM1_RS12830	COG0010	Belongs to the arginase family
AM1_RS12835	COG0375	protein maturation
AM1_RS12855	COG1116	anion transmembrane transporter activity
AM1_RS12865	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM1_RS12870	COG3266	domain, Protein
AM1_RS12870	COG0515	serine threonine protein kinase
AM1_RS12885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM1_RS12910	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
AM1_RS12925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM1_RS12930	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM1_RS12940	COG0717	Belongs to the dCTP deaminase family
AM1_RS12945	COG3751	2OG-Fe(II) oxygenase superfamily
AM1_RS12950	COG2099	Precorrin-6x reductase
AM1_RS12955	COG1716	ATPase activity
AM1_RS12955	COG5001	Diguanylate cyclase
AM1_RS12960	COG0335	large ribosomal subunit rRNA binding
AM1_RS12970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM1_RS12975	COG0250	Participates in transcription elongation, termination and antitermination
AM1_RS12980	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AM1_RS12985	COG0081	regulation of translation
AM1_RS12990	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM1_RS12995	COG0222	ribosome binding
AM1_RS13000	COG1799	cell septum assembly
AM1_RS13015	COG0842	Transport permease protein
AM1_RS13015	COG1716	ATPase activity
AM1_RS13015	COG1131	(ABC) transporter
AM1_RS13025	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM1_RS13030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM1_RS13035	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM1_RS13040	COG3409	Peptidoglycan-binding domain 1 protein
AM1_RS13040	COG3429	Glucose-6-phosphate dehydrogenase subunit
AM1_RS13050	COG1797	cobyrinic acid a,c-diamide synthase activity
AM1_RS13060	COG0632	four-way junction helicase activity
AM1_RS13080	COG0596	Alpha beta hydrolase
AM1_RS13100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AM1_RS13100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM1_RS13110	COG2119	membrane
AM1_RS13115	COG2119	membrane
AM1_RS13140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM1_RS13150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM1_RS13160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM1_RS13180	COG0163	prenyltransferase activity
AM1_RS13200	COG0504	CTP synthase activity
AM1_RS13205	COG1940	carbohydrate kinase activity
AM1_RS13210	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AM1_RS13240	COG1253	flavin adenine dinucleotide binding
AM1_RS13250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM1_RS13295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM1_RS13310	COG4243	Vitamin k epoxide reductase
AM1_RS13315	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM1_RS13320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AM1_RS13330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM1_RS13350	COG0601	transmembrane transport
AM1_RS13355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM1_RS13415	COG0515	serine threonine protein kinase
AM1_RS13415	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS13420	COG1175	transmembrane transport
AM1_RS13470	COG1131	(ABC) transporter
AM1_RS13505	COG0038	chloride channel
AM1_RS13515	COG1011	Hydrolase
AM1_RS13535	COG2223	nitrite transmembrane transporter activity
AM1_RS13540	COG3659	wide pore channel activity
AM1_RS13545	COG0243	molybdopterin cofactor binding
AM1_RS13550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM1_RS13555	COG0778	Nitroreductase
AM1_RS13615	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AM1_RS13625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM1_RS13670	COG2166	iron-sulfur cluster assembly
AM1_RS13675	COG0523	cobalamin synthesis protein
AM1_RS13740	COG3220	belongs to the UPF0276 family
AM1_RS13765	COG0523	cobalamin synthesis protein
AM1_RS13775	COG2197	response regulator
AM1_RS13805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM1_RS13840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM1_RS13850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM1_RS13850	COG4451	ribulose bisphosphate carboxylase, small
AM1_RS13855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM1_RS13865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM1_RS13870	COG0302	gtp cyclohydrolase
AM1_RS13875	COG0523	cobalamin synthesis protein
AM1_RS13910	COG3657	addiction module killer protein
AM1_RS13940	COG0523	cobalamin synthesis protein
AM1_RS13945	COG0113	porphobilinogen synthase activity
AM1_RS13950	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM1_RS13950	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM1_RS13955	COG1121	(ABC) transporter
AM1_RS13960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM1_RS13990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM1_RS13995	COG1472	Belongs to the glycosyl hydrolase 3 family
AM1_RS14020	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM1_RS14025	COG0321	lipoyl(octanoyl) transferase activity
AM1_RS14030	COG0314	molybdopterin synthase activity
AM1_RS14045	COG0706	membrane insertase activity
AM1_RS14055	COG0594	ribonuclease P activity
AM1_RS14060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM1_RS14065	COG0592	DNA-directed DNA polymerase activity
AM1_RS14080	COG0463	Glycosyl transferase, family 2
AM1_RS14085	COG0745	RESPONSE REGULATOR receiver
AM1_RS14090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM1_RS14095	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AM1_RS14100	COG2211	Major facilitator Superfamily
AM1_RS14110	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS14130	COG1012	belongs to the aldehyde dehydrogenase family
AM1_RS14145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM1_RS14165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM1_RS14180	COG4251	negative regulation of phosphorylation
AM1_RS14190	COG1994	Peptidase M50
AM1_RS14195	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM1_RS14210	COG2027	D-alanyl-D-alanine carboxypeptidase
AM1_RS14275	COG0681	Belongs to the peptidase S26 family
AM1_RS14285	COG0129	dihydroxy-acid dehydratase activity
AM1_RS14300	COG2319	Wd-40 repeat
AM1_RS14300	COG3903	Transcriptional regulator
AM1_RS14305	COG0824	Thioesterase
AM1_RS14335	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM1_RS14340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM1_RS14350	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM1_RS14360	COG3842	ATPase activity
AM1_RS14365	COG0515	serine threonine protein kinase
AM1_RS14365	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS14370	COG0629	single-stranded DNA binding
AM1_RS14375	COG0628	permease
AM1_RS14380	COG0752	glycyl-tRNA synthetase alpha subunit
AM1_RS14410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM1_RS14425	COG0316	Belongs to the HesB IscA family
AM1_RS14460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM1_RS14465	COG2274	protein secretion by the type I secretion system
AM1_RS14495	COG4978	Transcriptional regulator
AM1_RS14495	COG0789	Transcriptional regulator
AM1_RS14510	COG3266	domain, Protein
AM1_RS14510	COG0515	serine threonine protein kinase
AM1_RS14530	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AM1_RS14530	COG2273	Hydrolase Family 16
AM1_RS14535	COG0438	transferase activity, transferring glycosyl groups
AM1_RS14540	COG0659	secondary active sulfate transmembrane transporter activity
AM1_RS14545	COG0475	glutathione-regulated potassium exporter activity
AM1_RS14550	COG1006	Multisubunit Na H antiporter MnhC subunit
AM1_RS14555	COG0651	ATP synthesis coupled electron transport
AM1_RS14595	COG2146	nitrite reductase [NAD(P)H] activity
AM1_RS14600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM1_RS14610	COG0515	serine threonine protein kinase
AM1_RS14625	COG0459	protein refolding
AM1_RS14645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM1_RS14670	COG0492	ferredoxin-NADP+ reductase activity
AM1_RS14695	COG0745	RESPONSE REGULATOR receiver
AM1_RS14700	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM1_RS14705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM1_RS14710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS14720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS14740	COG0745	RESPONSE REGULATOR receiver
AM1_RS14745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM1_RS14745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM1_RS14750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM1_RS14775	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM1_RS14775	COG0596	Alpha beta hydrolase
AM1_RS14785	COG3852	Histidine kinase
AM1_RS14790	COG0492	ferredoxin-NADP+ reductase activity
AM1_RS14800	COG3903	Transcriptional regulator
AM1_RS14800	COG2319	Wd-40 repeat
AM1_RS14840	COG3328	transposase activity
AM1_RS14845	COG3328	transposase activity
AM1_RS14850	COG3328	transposase activity
AM1_RS14890	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM1_RS14945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM1_RS14970	COG0251	oxidation-reduction process
AM1_RS14985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM1_RS14985	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM1_RS15015	COG0028	Belongs to the TPP enzyme family
AM1_RS15025	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AM1_RS15040	COG0469	pyruvate kinase activity
AM1_RS15045	COG1959	2 iron, 2 sulfur cluster binding
AM1_RS15085	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AM1_RS15090	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM1_RS15100	COG5002	protein histidine kinase activity
AM1_RS15100	COG5001	Diguanylate cyclase
AM1_RS15105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM1_RS15115	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM1_RS15120	COG0649	NAD binding
AM1_RS15140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM1_RS15155	COG2211	Major facilitator Superfamily
AM1_RS15160	COG1722	exodeoxyribonuclease VII activity
AM1_RS15165	COG1570	exodeoxyribonuclease VII activity
AM1_RS15170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM1_RS15175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM1_RS15180	COG1120	ATPase activity
AM1_RS15185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM1_RS15190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM1_RS15200	COG0492	ferredoxin-NADP+ reductase activity
AM1_RS15215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM1_RS15270	COG3588	fructose-bisphosphate aldolase
AM1_RS15280	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM1_RS15315	COG2207	Transcriptional regulator
AM1_RS15320	COG4771	TonB-dependent receptor
AM1_RS15340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM1_RS15370	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM1_RS15380	COG4607	ABC-type enterochelin transport system periplasmic component
AM1_RS15400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM1_RS15435	COG0783	Belongs to the Dps family
AM1_RS15440	COG0848	biopolymer transport protein
AM1_RS15445	COG0811	peptide transport
AM1_RS15455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM1_RS15460	COG1120	ATPase activity
AM1_RS15465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM1_RS15480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM1_RS15515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AM1_RS15520	COG0052	Belongs to the universal ribosomal protein uS2 family
AM1_RS15525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM1_RS15555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM1_RS15560	COG0768	penicillin binding
AM1_RS15565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM1_RS15590	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AM1_RS15595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM1_RS15600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM1_RS15605	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM1_RS15610	COG0740	serine-type endopeptidase activity
AM1_RS15615	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM1_RS15625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM1_RS15635	COG5002	protein histidine kinase activity
AM1_RS15635	COG5001	Diguanylate cyclase
AM1_RS15640	COG1193	negative regulation of DNA recombination
AM1_RS15660	COG0745	RESPONSE REGULATOR receiver
AM1_RS15665	COG0789	Transcriptional regulator
AM1_RS15680	COG2205	protein histidine kinase activity
AM1_RS15690	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM1_RS15705	COG0288	reversible hydration of carbon dioxide
AM1_RS15715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM1_RS15755	COG0745	RESPONSE REGULATOR receiver
AM1_RS15790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM1_RS15795	COG0581	inorganic phosphate transmembrane transporter activity
AM1_RS15800	COG0573	inorganic phosphate transmembrane transporter activity
AM1_RS15805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM1_RS15810	COG0640	Transcriptional regulator
AM1_RS15835	COG4249	Peptidase C14 caspase catalytic subunit p20
AM1_RS15835	COG2319	Wd-40 repeat
AM1_RS15840	COG5001	Diguanylate cyclase
AM1_RS15840	COG4251	negative regulation of phosphorylation
AM1_RS15840	COG3706	GGDEF domain
AM1_RS15840	COG2203	Gaf domain
AM1_RS15850	COG3540	Alkaline phosphatase
AM1_RS15895	COG1748	Saccharopine dehydrogenase
AM1_RS15900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM1_RS15910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM1_RS15925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM1_RS15930	COG0318	PFAM AMP-dependent synthetase and ligase
AM1_RS15930	COG0204	Acyl-transferase
AM1_RS15940	COG0242	peptide deformylase activity
AM1_RS15970	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AM1_RS15975	COG0010	Belongs to the arginase family
AM1_RS15985	COG0154	amidase activity
AM1_RS15995	COG0004	ammonium transporteR
AM1_RS16000	COG0004	ammonium transporteR
AM1_RS16050	COG2385	sporulation resulting in formation of a cellular spore
AM1_RS16080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM1_RS16085	COG3540	Alkaline phosphatase
AM1_RS16135	COG2124	cytochrome p450
AM1_RS16145	COG2815	serine threonine protein kinase
AM1_RS16145	COG0515	serine threonine protein kinase
AM1_RS16150	COG2204	response regulator
AM1_RS16155	COG4191	Histidine kinase
AM1_RS16155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM1_RS16160	COG0784	Response regulator, receiver
AM1_RS16160	COG3437	response regulator, receiver
AM1_RS16165	COG4251	negative regulation of phosphorylation
AM1_RS16165	COG5001	Diguanylate cyclase
AM1_RS16165	COG3706	GGDEF domain
AM1_RS16165	COG2203	Gaf domain
AM1_RS16170	COG0116	Belongs to the methyltransferase superfamily
AM1_RS16175	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM1_RS16185	COG0822	iron-sulfur transferase activity
AM1_RS16195	COG0371	Dehydrogenase
AM1_RS16200	COG0436	Aminotransferase
AM1_RS16205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM1_RS16210	COG0569	domain protein
AM1_RS16215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM1_RS16225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM1_RS16230	COG0406	alpha-ribazole phosphatase activity
AM1_RS16260	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM1_RS16265	COG0268	Binds directly to 16S ribosomal RNA
AM1_RS16270	COG0084	hydrolase, TatD family'
AM1_RS16275	COG0085	RNA polymerase activity
AM1_RS16280	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM1_RS16285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM1_RS16290	COG2267	carboxylic ester hydrolase activity
AM1_RS16295	COG0534	Mate efflux family protein
AM1_RS16305	COG2022	thiamine diphosphate biosynthetic process
AM1_RS16320	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM1_RS16355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM1_RS16365	COG2226	methyltransferase
AM1_RS16395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM1_RS16435	COG0673	inositol 2-dehydrogenase activity
AM1_RS16465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM1_RS16470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM1_RS16475	COG0799	negative regulation of ribosome biogenesis
AM1_RS16495	COG0628	permease
AM1_RS16510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM1_RS16520	COG0515	serine threonine protein kinase
AM1_RS16520	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS16525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM1_RS16530	COG1215	transferase activity, transferring glycosyl groups
AM1_RS16540	COG3769	mannosylglycerate metabolic process
AM1_RS16550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM1_RS16570	COG2045	Belongs to the ComB family
AM1_RS16575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM1_RS16590	COG1732	Glycine betaine
AM1_RS16605	COG2082	Precorrin-8x methylmutase
AM1_RS16620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM1_RS16630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM1_RS16650	COG0483	inositol monophosphate 1-phosphatase activity
AM1_RS16660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM1_RS16675	COG0300	oxidoreductase activity
AM1_RS16690	COG0735	belongs to the Fur family
AM1_RS16695	COG0678	peroxiredoxin activity
AM1_RS16700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM1_RS16705	COG0723	plastoquinol--plastocyanin reductase activity
AM1_RS16745	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AM1_RS16760	COG3328	transposase activity
AM1_RS16815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM1_RS16830	COG3128	pkhd-type hydroxylase
AM1_RS16835	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM1_RS16840	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM1_RS16850	COG4251	negative regulation of phosphorylation
AM1_RS16850	COG3706	GGDEF domain
AM1_RS16850	COG5001	Diguanylate cyclase
AM1_RS16850	COG2203	Gaf domain
AM1_RS16855	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AM1_RS16870	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AM1_RS16875	COG0589	response to stress
AM1_RS16880	COG0659	secondary active sulfate transmembrane transporter activity
AM1_RS16885	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM1_RS16905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM1_RS16910	COG0745	RESPONSE REGULATOR receiver
AM1_RS16925	COG0861	Integral membrane protein TerC family
AM1_RS16945	COG0105	UTP biosynthetic process
AM1_RS16950	COG0671	phosphoesterase, PA-phosphatase related
AM1_RS16975	COG0784	Response regulator, receiver
AM1_RS16975	COG2198	Histidine kinase
AM1_RS16975	COG0643	Histidine kinase
AM1_RS16980	COG0840	transmembrane signaling receptor activity
AM1_RS16990	COG0745	RESPONSE REGULATOR receiver
AM1_RS16995	COG0784	Response regulator, receiver
AM1_RS17005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM1_RS17015	COG1876	peptidase activity
AM1_RS17020	COG0515	serine threonine protein kinase
AM1_RS17020	COG3266	domain, Protein
AM1_RS17025	COG4948	Mandelate Racemase Muconate Lactonizing
AM1_RS17030	COG0318	PFAM AMP-dependent synthetase and ligase
AM1_RS17045	COG1396	sequence-specific DNA binding
AM1_RS17060	COG3239	Fatty acid desaturase
AM1_RS17135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM1_RS17150	COG1132	(ABC) transporter
AM1_RS17180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM1_RS17185	COG0552	protein localization to endoplasmic reticulum
AM1_RS17190	COG2208	phosphoserine phosphatase activity
AM1_RS17200	COG0006	proline dipeptidase activity
AM1_RS17210	COG0730	response to heat
AM1_RS17220	COG0308	aminopeptidase N
AM1_RS17245	COG0432	Pfam Uncharacterised protein family UPF0047
AM1_RS17300	COG1940	carbohydrate kinase activity
AM1_RS17330	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM1_RS17340	COG2226	methyltransferase
AM1_RS17360	COG2319	Wd-40 repeat
AM1_RS17360	COG3903	Transcriptional regulator
AM1_RS17380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM1_RS17390	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM1_RS17420	COG3263	regulation of cellular component size
AM1_RS17425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM1_RS17440	COG2197	response regulator
AM1_RS17445	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM1_RS17450	COG2198	Histidine kinase
AM1_RS17450	COG0784	Response regulator, receiver
AM1_RS17450	COG2205	protein histidine kinase activity
AM1_RS17460	COG0701	Predicted permease
AM1_RS17470	COG0343	queuine tRNA-ribosyltransferase activity
AM1_RS17485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM1_RS17485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM1_RS17490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM1_RS17545	COG1201	RNA secondary structure unwinding
AM1_RS17550	COG4251	negative regulation of phosphorylation
AM1_RS17560	COG0784	Response regulator, receiver
AM1_RS17565	COG5001	Diguanylate cyclase
AM1_RS17565	COG5002	protein histidine kinase activity
AM1_RS17570	COG0484	heat shock protein binding
AM1_RS17580	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM1_RS17585	COG2081	HI0933 family
AM1_RS17590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM1_RS17600	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AM1_RS17610	COG2010	Cytochrome c
AM1_RS17615	COG2010	Cytochrome c
AM1_RS17620	COG2010	Cytochrome c
AM1_RS17630	COG2329	Antibiotic biosynthesis monooxygenase
AM1_RS17635	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS17645	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AM1_RS17665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM1_RS17715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM1_RS17740	COG0515	serine threonine protein kinase
AM1_RS17740	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS17755	COG0745	RESPONSE REGULATOR receiver
AM1_RS17760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM1_RS17765	COG1194	a g-specific adenine glycosylase
AM1_RS17800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS17805	COG2091	lysine biosynthetic process via aminoadipic acid
AM1_RS17810	COG0426	domain, Protein
AM1_RS17810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM1_RS17835	COG0511	ligase activity, forming carbon-carbon bonds
AM1_RS17840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM1_RS17850	COG0745	RESPONSE REGULATOR receiver
AM1_RS17855	COG3932	Exopolysaccharide synthesis, ExoD
AM1_RS17860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM1_RS17880	COG0181	hydroxymethylbilane synthase activity
AM1_RS17890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM1_RS17895	COG0205	6-phosphofructokinase activity
AM1_RS17900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM1_RS17910	COG3903	Transcriptional regulator
AM1_RS17910	COG2319	Wd-40 repeat
AM1_RS17915	COG0515	serine threonine protein kinase
AM1_RS17925	COG0792	nuclease activity
AM1_RS17935	COG0747	negative chemotaxis
AM1_RS17940	COG0633	Ferredoxin
AM1_RS17980	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM1_RS17985	COG1555	photosystem II stabilization
AM1_RS17995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM1_RS18010	COG0330	HflC and HflK could
AM1_RS18045	COG0501	Belongs to the peptidase M48B family
AM1_RS18050	COG0148	phosphopyruvate hydratase activity
AM1_RS18055	COG0346	lactoylglutathione lyase activity
AM1_RS18060	COG3659	wide pore channel activity
AM1_RS18065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM1_RS18070	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM1_RS18075	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AM1_RS18090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM1_RS18095	COG0483	inositol monophosphate 1-phosphatase activity
AM1_RS18100	COG0484	heat shock protein binding
AM1_RS18105	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AM1_RS18110	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM1_RS18135	COG0436	Aminotransferase
AM1_RS18140	COG1842	Phage shock protein A
AM1_RS18150	COG0667	Aldo Keto reductase
AM1_RS18155	COG0372	Belongs to the citrate synthase family
AM1_RS18195	COG0596	Alpha beta hydrolase
AM1_RS18220	COG0384	phenazine biosynthesis protein PhzF
AM1_RS18230	COG0438	transferase activity, transferring glycosyl groups
AM1_RS18275	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
AM1_RS18280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM1_RS18285	COG0515	serine threonine protein kinase
AM1_RS18305	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AM1_RS18310	COG5322	oxidoreductase activity
AM1_RS18330	COG2226	methyltransferase
AM1_RS18345	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM1_RS18355	COG0745	RESPONSE REGULATOR receiver
AM1_RS18360	COG4581	dead DEAH box helicase
AM1_RS18365	COG0643	Histidine kinase
AM1_RS18365	COG2198	Histidine kinase
AM1_RS18370	COG0840	transmembrane signaling receptor activity
AM1_RS18390	COG1573	uracil-dna glycosylase
AM1_RS18405	COG0750	zinc metalloprotease
AM1_RS18410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM1_RS18415	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AM1_RS18430	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AM1_RS18435	COG0215	cysteine-tRNA ligase activity
AM1_RS18450	COG1716	ATPase activity
AM1_RS18450	COG5001	Diguanylate cyclase
AM1_RS18460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM1_RS18465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM1_RS18475	COG3328	transposase activity
AM1_RS18535	COG3265	gluconokinase activity
AM1_RS18545	COG1121	(ABC) transporter
AM1_RS18550	COG0228	four-way junction DNA binding
AM1_RS18560	COG1702	phosphate starvation-inducible protein PhoH
AM1_RS18575	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM1_RS18580	COG0336	Belongs to the RNA methyltransferase TrmD family
AM1_RS18585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM1_RS18630	COG0702	epimerase
AM1_RS18645	COG2183	response to ionizing radiation
AM1_RS18665	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM1_RS18705	COG0006	proline dipeptidase activity
AM1_RS18710	COG0438	transferase activity, transferring glycosyl groups
AM1_RS18715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM1_RS18720	COG0456	acetyltransferase
AM1_RS18725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM1_RS18750	COG0697	spore germination
AM1_RS18765	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM1_RS18770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM1_RS18825	COG0697	spore germination
AM1_RS18830	COG2124	cytochrome p450
AM1_RS18845	COG0347	Belongs to the P(II) protein family
AM1_RS18860	COG2084	Dehydrogenase
AM1_RS18875	COG0583	DNA-binding transcription factor activity
AM1_RS18905	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM1_RS18910	COG1285	pathogenesis
AM1_RS18935	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AM1_RS18935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM1_RS18995	COG1366	Belongs to the anti-sigma-factor antagonist family
AM1_RS19025	COG2340	Cysteine-rich secretory protein family
AM1_RS19030	COG2304	oxidoreductase activity
AM1_RS19035	COG0640	Transcriptional regulator
AM1_RS19040	COG2912	Transglutaminase-like superfamily
AM1_RS19050	COG5002	protein histidine kinase activity
AM1_RS19060	COG0557	exoribonuclease II activity
AM1_RS19065	COG0704	Plays a role in the regulation of phosphate uptake
AM1_RS19135	COG0137	argininosuccinate synthase activity
AM1_RS19145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM1_RS19160	COG1077	Cell shape determining protein MreB Mrl
AM1_RS19165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AM1_RS19185	COG1492	cobalamin metabolic process
AM1_RS19195	COG3956	TIGRFAM MazG family protein
AM1_RS19305	COG2720	vancomycin resistance protein
AM1_RS19320	COG0166	Belongs to the GPI family
AM1_RS19325	COG1716	ATPase activity
AM1_RS19335	COG2205	protein histidine kinase activity
AM1_RS19340	COG3022	response to hydroperoxide
AM1_RS19370	COG0784	Response regulator, receiver
AM1_RS19370	COG5002	protein histidine kinase activity
AM1_RS19370	COG2198	Histidine kinase
AM1_RS19385	COG1132	(ABC) transporter
AM1_RS19420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM1_RS19420	COG2022	thiamine diphosphate biosynthetic process
AM1_RS19435	COG4249	Peptidase C14 caspase catalytic subunit p20
AM1_RS19435	COG2319	Wd-40 repeat
AM1_RS19480	COG2197	response regulator
AM1_RS19525	COG2203	Gaf domain
AM1_RS19525	COG3706	GGDEF domain
AM1_RS19525	COG4251	negative regulation of phosphorylation
AM1_RS19525	COG5001	Diguanylate cyclase
AM1_RS19530	COG0072	phenylalanine-tRNA ligase activity
AM1_RS19530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM1_RS19550	COG0515	serine threonine protein kinase
AM1_RS19555	COG0515	serine threonine protein kinase
AM1_RS19555	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS19560	COG0515	serine threonine protein kinase
AM1_RS19565	COG0515	serine threonine protein kinase
AM1_RS19575	COG0515	serine threonine protein kinase
AM1_RS19580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM1_RS19605	COG2890	protein-(glutamine-N5) methyltransferase activity
AM1_RS19615	COG0686	Belongs to the AlaDH PNT family
AM1_RS19635	COG2852	Protein conserved in bacteria
AM1_RS19655	COG3210	domain, Protein
AM1_RS19660	COG0612	Peptidase, M16
AM1_RS19670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM1_RS19675	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS19680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM1_RS19685	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM1_RS19695	COG1691	(AIR) carboxylase
AM1_RS19705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM1_RS19710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM1_RS19715	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
AM1_RS19725	COG1187	pseudouridine synthase activity
AM1_RS19730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM1_RS19745	COG0134	indole-3-glycerol-phosphate synthase activity
AM1_RS19750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM1_RS19755	COG0517	IMP dehydrogenase activity
AM1_RS19755	COG1994	Peptidase M50
AM1_RS19765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS19775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM1_RS19780	COG0284	orotidine-5'-phosphate decarboxylase activity
AM1_RS19785	COG2003	Belongs to the UPF0758 family
AM1_RS19790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM1_RS19805	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM1_RS19805	COG3264	Mechanosensitive ion channel
AM1_RS19810	COG1304	FMN binding
AM1_RS19820	COG0210	DNA helicase
AM1_RS19835	COG0531	amino acid
AM1_RS19855	COG0746	molybdenum cofactor guanylyltransferase activity
AM1_RS19860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM1_RS19865	COG0583	DNA-binding transcription factor activity
AM1_RS19875	COG0149	triose-phosphate isomerase activity
AM1_RS19885	COG1132	(ABC) transporter
AM1_RS19890	COG1196	nuclear chromosome segregation
AM1_RS19890	COG0741	lytic transglycosylase activity
AM1_RS19890	COG0739	heme binding
AM1_RS19940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM1_RS19940	COG1333	cytochrome c biogenesis protein
AM1_RS19975	COG0459	protein refolding
AM1_RS19980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM1_RS19985	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AM1_RS19995	COG0165	Argininosuccinate lyase
AM1_RS20005	COG0395	ABC-type sugar transport system, permease component
AM1_RS20020	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM1_RS20035	COG1214	PFAM Peptidase M22, glycoprotease
AM1_RS20040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM1_RS20050	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AM1_RS20055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM1_RS20055	COG0519	Catalyzes the synthesis of GMP from XMP
AM1_RS20065	COG2202	Pas domain
AM1_RS20065	COG2205	protein histidine kinase activity
AM1_RS20120	COG0534	Mate efflux family protein
AM1_RS20130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM1_RS20150	COG1132	(ABC) transporter
AM1_RS20160	COG3258	Cytochrome c
AM1_RS20175	COG0805	protein transport
AM1_RS20205	COG0793	Belongs to the peptidase S41A family
AM1_RS20210	COG1346	cytolysis
AM1_RS20215	COG1380	Effector of murein hydrolase LrgA
AM1_RS20220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM1_RS20285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM1_RS20315	COG2319	Wd-40 repeat
AM1_RS20315	COG1672	PFAM Archaeal ATPase
AM1_RS20320	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS20375	COG0519	Catalyzes the synthesis of GMP from XMP
AM1_RS20390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM1_RS20395	COG0187	DNA topoisomerase II activity
AM1_RS20395	COG1372	Participates in initiation and elongation during chromosome replication
AM1_RS20410	COG0170	dolichyl monophosphate biosynthetic process
AM1_RS20425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AM1_RS20430	COG0023	Translation Initiation Factor
AM1_RS20460	COG0788	formyltetrahydrofolate deformylase activity
AM1_RS20485	COG1070	Carbohydrate kinase
AM1_RS20560	COG5001	Diguanylate cyclase
AM1_RS20560	COG1716	ATPase activity
AM1_RS20565	COG0018	arginyl-trna synthetase
AM1_RS20575	COG2226	methyltransferase
AM1_RS20580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM1_RS20585	COG0515	serine threonine protein kinase
AM1_RS20585	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS20605	COG1316	TRANSCRIPTIONal
AM1_RS20615	COG1063	alcohol dehydrogenase
AM1_RS20625	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AM1_RS20635	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM1_RS20640	COG0539	negative regulation of cytoplasmic translation
AM1_RS20645	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM1_RS20660	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AM1_RS20670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM1_RS20675	COG2046	Belongs to the sulfate adenylyltransferase family
AM1_RS20685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM1_RS20695	COG1490	D-aminoacyl-tRNA deacylase activity
AM1_RS20700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM1_RS20710	COG3706	GGDEF domain
AM1_RS20710	COG5001	Diguanylate cyclase
AM1_RS20710	COG2203	Gaf domain
AM1_RS20710	COG4251	negative regulation of phosphorylation
AM1_RS20720	COG3240	lipase activity
AM1_RS20735	COG1215	transferase activity, transferring glycosyl groups
AM1_RS20750	COG0857	belongs to the CobB CobQ family
AM1_RS20760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM1_RS20770	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM1_RS20785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS20800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS20810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM1_RS20815	COG0662	Cupin 2, conserved barrel domain protein
AM1_RS20815	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM1_RS20835	COG0259	pyridoxamine-phosphate oxidase activity
AM1_RS20875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM1_RS20885	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AM1_RS20905	COG2319	Wd-40 repeat
AM1_RS20905	COG1672	PFAM Archaeal ATPase
AM1_RS20925	COG0515	serine threonine protein kinase
AM1_RS20930	COG0583	DNA-binding transcription factor activity
AM1_RS20935	COG0157	Belongs to the NadC ModD family
AM1_RS20940	COG1845	cytochrome c oxidase, subunit III
AM1_RS20945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM1_RS20950	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM1_RS20960	COG0109	protoheme IX farnesyltransferase activity
AM1_RS20965	COG1131	(ABC) transporter
AM1_RS20990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM1_RS21000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM1_RS21005	COG1381	Involved in DNA repair and RecF pathway recombination
AM1_RS21015	COG0438	transferase activity, transferring glycosyl groups
AM1_RS21015	COG0297	glycogen (starch) synthase activity
AM1_RS21020	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM1_RS21040	COG1543	Belongs to the glycosyl hydrolase 57 family
AM1_RS21045	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM1_RS21050	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AM1_RS21055	COG2894	cell division
AM1_RS21060	COG0850	regulation of cytokinetic process
AM1_RS21070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM1_RS21080	COG0601	transmembrane transport
AM1_RS21085	COG4166	transmembrane transport
AM1_RS21095	COG1587	Uroporphyrinogen-III synthase
AM1_RS21105	COG1595	DNA-templated transcription, initiation
AM1_RS21120	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM1_RS21125	COG3239	Fatty acid desaturase
AM1_RS21130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM1_RS21135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM1_RS21135	COG0758	DNA mediated transformation
AM1_RS21140	COG0242	peptide deformylase activity
AM1_RS21145	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AM1_RS21150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AM1_RS21155	COG0793	Belongs to the peptidase S41A family
AM1_RS21160	COG1078	dGTPase activity
AM1_RS21170	COG0328	RNA-DNA hybrid ribonuclease activity
AM1_RS21175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM1_RS21185	COG1836	PFAM Integral membrane protein DUF92
AM1_RS21200	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AM1_RS21285	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM1_RS21290	COG0088	Forms part of the polypeptide exit tunnel
AM1_RS21295	COG0089	rRNA binding
AM1_RS21300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AM1_RS21305	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM1_RS21310	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AM1_RS21315	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AM1_RS21320	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM1_RS21325	COG0255	Belongs to the universal ribosomal protein uL29 family
AM1_RS21330	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AM1_RS21335	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AM1_RS21340	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AM1_RS21345	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AM1_RS21350	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AM1_RS21355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM1_RS21360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AM1_RS21365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM1_RS21370	COG0200	Binds to the 23S rRNA
AM1_RS21375	COG0201	protein transport
AM1_RS21380	COG0563	adenylate kinase activity
AM1_RS21385	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM1_RS21445	COG4566	intracellular signal transduction
AM1_RS21450	COG2897	thiosulfate sulfurtransferase activity
AM1_RS21455	COG5635	Nacht domain
AM1_RS21455	COG2319	Wd-40 repeat
AM1_RS21465	COG2852	Protein conserved in bacteria
AM1_RS21475	COG1672	PFAM Archaeal ATPase
AM1_RS21475	COG2319	Wd-40 repeat
AM1_RS21480	COG4453	Protein conserved in bacteria
AM1_RS21490	COG1609	Transcriptional regulator
AM1_RS21555	COG2255	four-way junction helicase activity
AM1_RS21560	COG1690	Belongs to the RtcB family
AM1_RS21565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM1_RS21590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM1_RS21595	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM1_RS21605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS21625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM1_RS21630	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AM1_RS21635	COG1104	cysteine desulfurase activity
AM1_RS21645	COG5001	Diguanylate cyclase
AM1_RS21760	COG2264	protein methyltransferase activity
AM1_RS21780	COG0113	porphobilinogen synthase activity
AM1_RS21790	COG0133	tryptophan synthase activity
AM1_RS21815	COG0557	exoribonuclease II activity
AM1_RS21820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM1_RS21845	COG1064	alcohol dehydrogenase
AM1_RS21860	COG1324	tolerance protein
AM1_RS21880	COG1562	ergosterol biosynthetic process
AM1_RS21885	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AM1_RS21885	COG0493	'glutamate synthase
AM1_RS21895	COG2226	methyltransferase
AM1_RS21935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM1_RS21945	COG0640	Transcriptional regulator
AM1_RS21950	COG3118	belongs to the thioredoxin family
AM1_RS21955	COG1902	pentaerythritol trinitrate reductase activity
AM1_RS21970	COG1879	ABC-type sugar transport system periplasmic component
AM1_RS21975	COG1657	PFAM Prenyltransferase squalene oxidase
AM1_RS21990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM1_RS21995	COG0793	Belongs to the peptidase S41A family
AM1_RS22000	COG0438	transferase activity, transferring glycosyl groups
AM1_RS22005	COG1429	ligase activity, forming nitrogen-metal bonds
AM1_RS22010	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AM1_RS22020	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM1_RS22030	COG0612	Peptidase, M16
AM1_RS22035	COG0612	Peptidase, M16
AM1_RS22045	COG0489	protein tyrosine kinase activity
AM1_RS22045	COG3206	protein involved in exopolysaccharide biosynthesis
AM1_RS22080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM1_RS22090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM1_RS22155	COG0352	thiamine-phosphate diphosphorylase activity
AM1_RS22160	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM1_RS22170	COG3063	Type IV pilus biogenesis stability protein PilW
AM1_RS22175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM1_RS22180	COG0271	Belongs to the BolA IbaG family
AM1_RS22195	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM1_RS22205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM1_RS22205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM1_RS22215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM1_RS22220	COG0848	biopolymer transport protein
AM1_RS22225	COG0811	peptide transport
AM1_RS22235	COG0824	Thioesterase
AM1_RS22240	COG1672	PFAM Archaeal ATPase
AM1_RS22245	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AM1_RS22250	COG0681	Belongs to the peptidase S26 family
AM1_RS22255	COG0142	geranyltranstransferase activity
AM1_RS22260	COG0492	ferredoxin-NADP+ reductase activity
AM1_RS22270	COG0572	uridine kinase
AM1_RS22275	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM1_RS22280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM1_RS22290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS22300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM1_RS22305	COG0589	response to stress
AM1_RS22350	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AM1_RS22365	COG0586	Pfam SNARE associated Golgi protein
AM1_RS22400	COG2084	Dehydrogenase
AM1_RS22445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AM1_RS22450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM1_RS22455	COG1121	(ABC) transporter
AM1_RS22505	COG3063	Type IV pilus biogenesis stability protein PilW
AM1_RS22540	COG0793	Belongs to the peptidase S41A family
AM1_RS22550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AM1_RS22565	COG0723	plastoquinol--plastocyanin reductase activity
AM1_RS22570	COG2203	Gaf domain
AM1_RS22570	COG3706	GGDEF domain
AM1_RS22570	COG4251	negative regulation of phosphorylation
AM1_RS22570	COG5001	Diguanylate cyclase
AM1_RS22580	COG5001	Diguanylate cyclase
AM1_RS22580	COG5002	protein histidine kinase activity
AM1_RS22585	COG2234	aminopeptidase activity
AM1_RS22615	COG2319	Wd-40 repeat
AM1_RS22615	COG1672	PFAM Archaeal ATPase
AM1_RS22635	COG0604	alcohol dehydrogenase
AM1_RS22640	COG4191	Histidine kinase
AM1_RS22680	COG3237	CsbD-like
AM1_RS22685	COG5433	transposase activity
AM1_RS22710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM1_RS22715	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AM1_RS22785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM1_RS22800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM1_RS22805	COG0402	S-adenosylhomocysteine deaminase activity
AM1_RS22820	COG1136	(ABC) transporter
AM1_RS22820	COG0577	efflux transmembrane transporter activity
AM1_RS22825	COG1136	(ABC) transporter
AM1_RS22845	COG1555	photosystem II stabilization
AM1_RS22850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM1_RS22855	COG0517	IMP dehydrogenase activity
AM1_RS22855	COG1994	Peptidase M50
AM1_RS22860	COG0589	response to stress
AM1_RS22870	COG5002	protein histidine kinase activity
AM1_RS22880	COG3781	membrane
AM1_RS22895	COG0643	Histidine kinase
AM1_RS22895	COG0784	Response regulator, receiver
AM1_RS22895	COG2198	Histidine kinase
AM1_RS22905	COG5002	protein histidine kinase activity
AM1_RS22915	COG0668	transmembrane transport
AM1_RS22955	COG2205	protein histidine kinase activity
AM1_RS22975	COG1090	epimerase
AM1_RS22985	COG2201	protein-glutamate methylesterase activity
AM1_RS22990	COG0643	Histidine kinase
AM1_RS22990	COG0784	Response regulator, receiver
AM1_RS22990	COG2198	Histidine kinase
AM1_RS22995	COG0840	transmembrane signaling receptor activity
AM1_RS23005	COG0784	Response regulator, receiver
AM1_RS23010	COG3437	response regulator, receiver
AM1_RS23015	COG2226	methyltransferase
AM1_RS23025	COG0398	Pfam SNARE associated Golgi protein
AM1_RS23030	COG0398	Pfam SNARE associated Golgi protein
AM1_RS23065	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM1_RS23075	COG1361	Conserved repeat domain
AM1_RS23075	COG3266	domain, Protein
AM1_RS23075	COG2911	Protein conserved in bacteria
AM1_RS23080	COG0745	RESPONSE REGULATOR receiver
AM1_RS23090	COG1620	l-lactate permease
AM1_RS23110	COG0829	nickel cation binding
AM1_RS23115	COG0831	urea catabolic process
AM1_RS23125	COG0832	Belongs to the urease beta subunit family
AM1_RS23130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM1_RS23130	COG2205	protein histidine kinase activity
AM1_RS23140	COG0804	urea catabolic process
AM1_RS23190	COG1132	(ABC) transporter
AM1_RS23195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM1_RS23200	COG0033	Phosphoglucomutase
AM1_RS23225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM1_RS23250	COG2205	protein histidine kinase activity
AM1_RS23250	COG2198	Histidine kinase
AM1_RS23250	COG0784	Response regulator, receiver
AM1_RS23255	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AM1_RS23260	COG0009	L-threonylcarbamoyladenylate synthase
AM1_RS23265	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AM1_RS23290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM1_RS23300	COG5002	protein histidine kinase activity
AM1_RS23310	COG5433	transposase activity
AM1_RS23315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM1_RS23320	COG0514	ATP-dependent DNA helicase (RecQ)
AM1_RS23340	COG2124	cytochrome p450
AM1_RS23375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM1_RS23380	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AM1_RS23385	COG1116	anion transmembrane transporter activity
AM1_RS23385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM1_RS23390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM1_RS23395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM1_RS23400	COG0745	RESPONSE REGULATOR receiver
AM1_RS23405	COG5002	protein histidine kinase activity
AM1_RS23460	COG3266	domain, Protein
AM1_RS23460	COG0515	serine threonine protein kinase
AM1_RS23480	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AM1_RS23485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM1_RS23500	COG1077	Cell shape determining protein MreB Mrl
AM1_RS23505	COG1175	transmembrane transport
AM1_RS23515	COG1716	ATPase activity
AM1_RS23520	COG0505	Belongs to the CarA family
AM1_RS23525	COG0596	Alpha beta hydrolase
AM1_RS23535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM1_RS23545	COG1366	Belongs to the anti-sigma-factor antagonist family
AM1_RS23555	COG0673	inositol 2-dehydrogenase activity
AM1_RS23565	COG0783	Belongs to the Dps family
AM1_RS23575	COG3937	granule-associated protein
AM1_RS23595	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS23595	COG0515	serine threonine protein kinase
AM1_RS23635	COG3268	Saccharopine dehydrogenase
AM1_RS23645	COG3657	addiction module killer protein
AM1_RS23650	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM1_RS23655	COG0756	dUTP diphosphatase activity
AM1_RS23665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM1_RS23675	COG5001	Diguanylate cyclase
AM1_RS23675	COG1716	ATPase activity
AM1_RS23680	COG1196	nuclear chromosome segregation
AM1_RS23680	COG3264	Mechanosensitive ion channel
AM1_RS23700	COG1073	alpha beta
AM1_RS23730	COG2032	superoxide dismutase activity
AM1_RS23765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM1_RS23775	COG3659	wide pore channel activity
AM1_RS23795	COG0501	Belongs to the peptidase M48B family
AM1_RS23805	COG0481	GTPase activity
AM1_RS23810	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM1_RS23830	COG5002	protein histidine kinase activity
AM1_RS23835	COG0745	RESPONSE REGULATOR receiver
AM1_RS23845	COG0786	glutamate:sodium symporter activity
AM1_RS23850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM1_RS23885	COG0714	Associated with various cellular activities
AM1_RS23890	COG0714	Associated with various cellular activities
AM1_RS23980	COG0438	transferase activity, transferring glycosyl groups
AM1_RS23985	COG3903	Transcriptional regulator
AM1_RS23985	COG2319	Wd-40 repeat
AM1_RS24000	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM1_RS24015	COG2205	protein histidine kinase activity
AM1_RS24015	COG5002	protein histidine kinase activity
AM1_RS24015	COG0784	Response regulator, receiver
AM1_RS24050	COG0668	transmembrane transport
AM1_RS24095	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AM1_RS24105	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM1_RS24110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM1_RS24120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM1_RS24135	COG0583	DNA-binding transcription factor activity
AM1_RS24185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM1_RS24195	COG2259	Doxx family
AM1_RS24200	COG0305	Participates in initiation and elongation during chromosome replication
AM1_RS24200	COG1372	Participates in initiation and elongation during chromosome replication
AM1_RS24200	COG1372	Participates in initiation and elongation during chromosome replication
AM1_RS24200	COG0305	Participates in initiation and elongation during chromosome replication
AM1_RS24205	COG0359	binds to the 23S rRNA
AM1_RS24250	COG3266	domain, Protein
AM1_RS24250	COG0515	serine threonine protein kinase
AM1_RS24260	COG1187	pseudouridine synthase activity
AM1_RS24265	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AM1_RS24270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM1_RS24280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM1_RS24285	COG1799	cell septum assembly
AM1_RS24290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM1_RS24300	COG3842	ATPase activity
AM1_RS24310	COG0596	Alpha beta hydrolase
AM1_RS24320	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM1_RS24325	COG0739	heme binding
AM1_RS24345	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM1_RS24350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM1_RS24360	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM1_RS24365	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM1_RS24370	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AM1_RS24375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM1_RS24375	COG4451	ribulose bisphosphate carboxylase, small
AM1_RS24380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM1_RS24385	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM1_RS24390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM1_RS24395	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM1_RS24420	COG1597	lipid kinase activity
AM1_RS24420	COG1803	Methylglyoxal synthase
AM1_RS24480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AM1_RS24495	COG1444	tRNA N-acetyltransferase activity
AM1_RS24510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM1_RS24540	COG1606	tRNA processing
AM1_RS24545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AM1_RS24555	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AM1_RS24585	COG0123	including yeast histone deacetylase and acetoin utilization protein
AM1_RS24605	COG4249	Peptidase C14 caspase catalytic subunit p20
AM1_RS24605	COG2319	Wd-40 repeat
AM1_RS24615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM1_RS24620	COG1480	7TM receptor with intracellular HD hydrolase
AM1_RS24635	COG0516	GMP reductase activity
AM1_RS24635	COG0517	IMP dehydrogenase activity
AM1_RS24650	COG3118	belongs to the thioredoxin family
AM1_RS24670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS24715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM1_RS24735	COG0617	tRNA 3'-terminal CCA addition
AM1_RS24760	COG4977	sequence-specific DNA binding
AM1_RS24760	COG1917	Cupin 2, conserved barrel domain protein
AM1_RS24765	COG2319	Wd-40 repeat
AM1_RS24765	COG3903	Transcriptional regulator
AM1_RS24795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM1_RS24800	COG0515	serine threonine protein kinase
AM1_RS24800	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS24815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS24820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM1_RS24830	COG2135	peptidase activity
AM1_RS24835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM1_RS24855	COG0347	Belongs to the P(II) protein family
AM1_RS24865	COG0450	alkyl hydroperoxide reductase
AM1_RS24875	COG0194	GDP metabolic process
AM1_RS24880	COG2052	Domain of unknown function (DUF370)
AM1_RS24885	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AM1_RS24910	COG0528	UMP kinase activity
AM1_RS24915	COG0233	cytoplasmic translational termination
AM1_RS24925	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AM1_RS24945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM1_RS24950	COG0193	aminoacyl-tRNA hydrolase activity
AM1_RS24960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM1_RS24970	COG0346	lactoylglutathione lyase activity
AM1_RS24980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM1_RS24985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM1_RS24990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM1_RS25000	COG2048	Heterodisulfide reductase, subunit B
AM1_RS25010	COG2205	protein histidine kinase activity
AM1_RS25010	COG3437	response regulator, receiver
AM1_RS25010	COG3850	Histidine kinase
AM1_RS25010	COG4999	Histidine kinase
AM1_RS25015	COG0556	nucleotide-excision repair
AM1_RS25055	COG5002	protein histidine kinase activity
AM1_RS25075	COG1234	tRNA 3'-trailer cleavage
AM1_RS25090	COG0297	glycogen (starch) synthase activity
AM1_RS25100	COG0438	transferase activity, transferring glycosyl groups
AM1_RS25105	COG0438	transferase activity, transferring glycosyl groups
AM1_RS25110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM1_RS25115	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM1_RS25125	COG0793	Belongs to the peptidase S41A family
AM1_RS25135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AM1_RS25140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM1_RS25145	COG0724	RNA recognition motif
AM1_RS25150	COG0482	sulfurtransferase activity
AM1_RS25165	COG1022	Amp-dependent synthetase and ligase
AM1_RS25175	COG1429	ligase activity, forming nitrogen-metal bonds
AM1_RS25200	COG1994	Peptidase M50
AM1_RS25200	COG0517	IMP dehydrogenase activity
AM1_RS25205	COG0095	Lipoate-protein ligase
AM1_RS25220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM1_RS25225	COG0189	ligase activity
AM1_RS25230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM1_RS25265	COG4279	zinc finger
AM1_RS25280	COG1215	transferase activity, transferring glycosyl groups
AM1_RS25295	COG0514	ATP-dependent DNA helicase (RecQ)
AM1_RS25320	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM1_RS25330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM1_RS25330	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AM1_RS25345	COG0577	efflux transmembrane transporter activity
AM1_RS25355	COG4399	Belongs to the UPF0754 family
AM1_RS25360	COG1131	(ABC) transporter
AM1_RS25365	COG0631	protein serine/threonine phosphatase activity
AM1_RS25370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM1_RS25375	COG3937	granule-associated protein
AM1_RS25380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM1_RS25395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM1_RS25395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM1_RS25425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM1_RS25435	COG5002	protein histidine kinase activity
AM1_RS25435	COG5001	Diguanylate cyclase
AM1_RS25440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM1_RS25460	COG0628	permease
AM1_RS25470	COG0003	Pfam Anion-transporting ATPase
AM1_RS25475	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS25480	COG0825	malonyl-CoA metabolic process
AM1_RS25485	COG0300	oxidoreductase activity
AM1_RS25490	COG0302	gtp cyclohydrolase
AM1_RS25505	COG2205	protein histidine kinase activity
AM1_RS25505	COG0784	Response regulator, receiver
AM1_RS25525	COG0418	dihydroorotase activity
AM1_RS25535	COG2994	toxin metabolic process
AM1_RS25560	COG0668	transmembrane transport
AM1_RS25605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM1_RS25625	COG2204	response regulator
AM1_RS25715	COG2319	Wd-40 repeat
AM1_RS25715	COG1672	PFAM Archaeal ATPase
AM1_RS25720	COG2205	protein histidine kinase activity
AM1_RS25720	COG5002	protein histidine kinase activity
AM1_RS25720	COG0784	Response regulator, receiver
AM1_RS25725	COG0121	glutamine amidotransferase
AM1_RS25730	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM1_RS25735	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AM1_RS25740	COG0443	Heat shock 70 kDa protein
AM1_RS25745	COG0484	heat shock protein binding
AM1_RS25760	COG3046	protein related to deoxyribodipyrimidine photolyase
AM1_RS25780	COG0515	serine threonine protein kinase
AM1_RS25790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM1_RS25800	COG2205	protein histidine kinase activity
AM1_RS25800	COG0784	Response regulator, receiver
AM1_RS25800	COG5002	protein histidine kinase activity
AM1_RS25810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM1_RS25845	COG1216	Glycosyl transferase, family 2
AM1_RS25875	COG1132	(ABC) transporter
AM1_RS25880	COG1215	transferase activity, transferring glycosyl groups
AM1_RS25885	COG1045	serine acetyltransferase
AM1_RS25905	COG0438	transferase activity, transferring glycosyl groups
AM1_RS25910	COG0438	transferase activity, transferring glycosyl groups
AM1_RS25925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM1_RS25935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM1_RS25960	COG0316	Belongs to the HesB IscA family
AM1_RS25965	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AM1_RS25965	COG0662	Cupin 2, conserved barrel domain protein
AM1_RS25985	COG2385	sporulation resulting in formation of a cellular spore
AM1_RS25990	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AM1_RS26000	COG1131	(ABC) transporter
AM1_RS26010	COG0473	3-isopropylmalate dehydrogenase activity
AM1_RS26020	COG0515	serine threonine protein kinase
AM1_RS26020	COG3266	domain, Protein
AM1_RS26030	COG1494	fructose-1,6-bisphosphatase
AM1_RS26035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM1_RS26040	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM1_RS26050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM1_RS26060	COG0367	asparagine synthase
AM1_RS26120	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM1_RS26125	COG0138	bifunctional purine biosynthesis protein purh
AM1_RS26130	COG2124	cytochrome p450
AM1_RS26145	COG4991	sh3 domain protein
AM1_RS26145	COG3064	Membrane
AM1_RS26145	COG0515	serine threonine protein kinase
AM1_RS26150	COG1801	Protein of unknown function DUF72
AM1_RS26155	COG0488	(ABC) transporter
AM1_RS26165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM1_RS26170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM1_RS26180	COG0107	imidazoleglycerol-phosphate synthase activity
AM1_RS26200	COG3394	polysaccharide catabolic process
AM1_RS26210	COG1032	radical SAM domain protein
AM1_RS26220	COG0523	cobalamin synthesis protein
AM1_RS26390	COG1073	alpha beta
AM1_RS26495	COG0739	heme binding
AM1_RS26565	COG4251	negative regulation of phosphorylation
AM1_RS26575	COG0784	Response regulator, receiver
AM1_RS26580	COG4251	negative regulation of phosphorylation
AM1_RS26585	COG1846	Transcriptional regulator
AM1_RS26590	COG0697	spore germination
AM1_RS26600	COG1950	PFAM Membrane protein of
AM1_RS26605	COG0435	Glutathione S-transferase
AM1_RS26615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM1_RS26620	COG0776	regulation of translation
AM1_RS26680	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM1_RS26685	COG1185	polyribonucleotide nucleotidyltransferase activity
AM1_RS26690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM1_RS26700	COG4251	negative regulation of phosphorylation
AM1_RS26715	COG0326	Molecular chaperone. Has ATPase activity
AM1_RS26730	COG0431	NADPH-dependent FMN reductase
AM1_RS26740	COG0515	serine threonine protein kinase
AM1_RS26740	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS26760	COG1160	GTP binding
AM1_RS26780	COG0483	inositol monophosphate 1-phosphatase activity
AM1_RS26785	COG4178	(ABC) transporter
AM1_RS26835	COG1733	regulation of RNA biosynthetic process
AM1_RS26845	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM1_RS26845	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM1_RS26865	COG2988	succinylglutamate desuccinylase activity
AM1_RS26870	COG3706	GGDEF domain
AM1_RS26900	COG2319	Wd-40 repeat
AM1_RS26900	COG3903	Transcriptional regulator
AM1_RS26940	COG0004	ammonium transporteR
AM1_RS26960	COG1662	PFAM IS1 transposase
AM1_RS27005	COG0410	ABC transporter
AM1_RS27010	COG0411	ABC transporter
AM1_RS27030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM1_RS27090	COG0716	FMN binding
AM1_RS27095	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AM1_RS27100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM1_RS27105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM1_RS27110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM1_RS27125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM1_RS27135	COG2133	pyrroloquinoline quinone binding
AM1_RS27140	COG2319	Wd-40 repeat
AM1_RS27140	COG3903	Transcriptional regulator
AM1_RS27150	COG2165	general secretion pathway protein
AM1_RS27205	COG1271	oxidase subunit
AM1_RS27245	COG1131	(ABC) transporter
AM1_RS27260	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM1_RS27290	COG0438	transferase activity, transferring glycosyl groups
AM1_RS27300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM1_RS27310	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM1_RS27320	COG0405	Gamma-glutamyltransferase
AM1_RS27345	COG0076	glutamate decarboxylase activity
AM1_RS27375	COG4191	Histidine kinase
AM1_RS27390	COG2205	protein histidine kinase activity
AM1_RS27390	COG0784	Response regulator, receiver
AM1_RS27395	COG3903	Transcriptional regulator
AM1_RS27395	COG2319	Wd-40 repeat
AM1_RS27415	COG0644	oxidoreductase
AM1_RS27440	COG0604	alcohol dehydrogenase
AM1_RS27455	COG2909	trisaccharide binding
AM1_RS27460	COG2909	trisaccharide binding
AM1_RS27560	COG4977	sequence-specific DNA binding
AM1_RS27620	COG0702	epimerase
AM1_RS27635	COG0582	viral genome integration into host DNA
AM1_RS27645	COG0582	viral genome integration into host DNA
AM1_RS27675	COG0534	Mate efflux family protein
AM1_RS27680	COG0783	Belongs to the Dps family
AM1_RS27695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM1_RS27710	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS27745	COG0475	glutathione-regulated potassium exporter activity
AM1_RS27760	COG1484	DNA-dependent DNA replication
AM1_RS27765	COG4584	PFAM Integrase catalytic
AM1_RS27830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS27840	COG0776	regulation of translation
AM1_RS27870	COG4227	nucleotidyltransferase activity
AM1_RS27885	COG4974	Belongs to the 'phage' integrase family
AM1_RS27940	COG3063	Type IV pilus biogenesis stability protein PilW
AM1_RS27955	COG5001	Diguanylate cyclase
AM1_RS27955	COG4251	negative regulation of phosphorylation
AM1_RS27955	COG3706	GGDEF domain
AM1_RS27955	COG2203	Gaf domain
AM1_RS27995	COG1252	NADH dehydrogenase
AM1_RS28000	COG4221	oxidoreductase activity
AM1_RS28025	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
AM1_RS28050	COG3903	Transcriptional regulator
AM1_RS28050	COG2319	Wd-40 repeat
AM1_RS28055	COG2319	Wd-40 repeat
AM1_RS28055	COG3903	Transcriptional regulator
AM1_RS28090	COG1917	Cupin 2, conserved barrel domain protein
AM1_RS28090	COG4977	sequence-specific DNA binding
AM1_RS28110	COG4584	PFAM Integrase catalytic
AM1_RS28115	COG1484	DNA-dependent DNA replication
AM1_RS28125	COG3328	transposase activity
AM1_RS28210	COG0698	ribose 5-phosphate isomerase
AM1_RS28225	COG2165	general secretion pathway protein
AM1_RS28290	COG1309	transcriptional regulator
AM1_RS28295	COG4585	Histidine kinase
AM1_RS28330	COG0515	serine threonine protein kinase
AM1_RS28355	COG0640	Transcriptional regulator
AM1_RS28360	COG2198	Histidine kinase
AM1_RS28360	COG0784	Response regulator, receiver
AM1_RS28360	COG2205	protein histidine kinase activity
AM1_RS28375	COG2197	response regulator
AM1_RS28395	COG2197	response regulator
AM1_RS28400	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM1_RS28400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM1_RS28410	COG1917	Cupin 2, conserved barrel domain protein
AM1_RS28410	COG4977	sequence-specific DNA binding
AM1_RS28415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM1_RS28420	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AM1_RS28425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM1_RS28430	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM1_RS28455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM1_RS28465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM1_RS28470	COG0745	RESPONSE REGULATOR receiver
AM1_RS28475	COG3850	Histidine kinase
AM1_RS28475	COG4999	Histidine kinase
AM1_RS28475	COG2205	protein histidine kinase activity
AM1_RS28475	COG3437	response regulator, receiver
AM1_RS28480	COG0589	response to stress
AM1_RS28485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM1_RS28490	COG0589	response to stress
AM1_RS28535	COG0697	spore germination
AM1_RS28540	COG0189	ligase activity
AM1_RS28565	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AM1_RS28585	COG0493	'glutamate synthase
AM1_RS28595	COG0784	Response regulator, receiver
AM1_RS28595	COG2198	Histidine kinase
AM1_RS28595	COG5002	protein histidine kinase activity
AM1_RS28600	COG2205	protein histidine kinase activity
AM1_RS28600	COG0784	Response regulator, receiver
AM1_RS28615	COG0306	phosphate transporter
AM1_RS28620	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS28625	COG0515	serine threonine protein kinase
AM1_RS28625	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS28630	COG0070	glutamate synthase
AM1_RS28630	COG0069	glutamate synthase activity
AM1_RS28630	COG0067	glutamate synthase
AM1_RS28650	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AM1_RS28660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM1_RS28665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM1_RS28670	COG5002	protein histidine kinase activity
AM1_RS28675	COG3659	wide pore channel activity
AM1_RS28680	COG0588	phosphoglycerate mutase activity
AM1_RS28690	COG0667	Aldo Keto reductase
AM1_RS28705	COG1132	(ABC) transporter
AM1_RS28715	COG1819	glycosyl
AM1_RS28735	COG0745	RESPONSE REGULATOR receiver
AM1_RS28740	COG1254	Belongs to the acylphosphatase family
AM1_RS28745	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM1_RS28905	COG1484	DNA-dependent DNA replication
AM1_RS28910	COG4584	PFAM Integrase catalytic
AM1_RS28920	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM1_RS28925	COG4191	Histidine kinase
AM1_RS28940	COG0739	heme binding
AM1_RS29020	COG2226	methyltransferase
AM1_RS29045	COG0668	transmembrane transport
AM1_RS29065	COG0724	RNA recognition motif
AM1_RS29080	COG1309	transcriptional regulator
AM1_RS29140	COG0724	RNA recognition motif
AM1_RS29170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM1_RS29210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM1_RS29215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM1_RS29220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM1_RS29240	COG0724	RNA recognition motif
AM1_RS29295	COG5001	Diguanylate cyclase
AM1_RS29295	COG1716	ATPase activity
AM1_RS29320	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS29325	COG4221	oxidoreductase activity
AM1_RS29345	COG1169	isochorismate synthase
AM1_RS29350	COG1902	pentaerythritol trinitrate reductase activity
AM1_RS29385	COG3744	PilT protein domain protein
AM1_RS29390	COG0582	viral genome integration into host DNA
AM1_RS29425	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM1_RS29440	COG0783	Belongs to the Dps family
AM1_RS29455	COG0390	transport system, permease component
AM1_RS29460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM1_RS29470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM1_RS29490	COG1120	ATPase activity
AM1_RS29495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM1_RS29500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM1_RS29505	COG0848	biopolymer transport protein
AM1_RS29510	COG0811	peptide transport
AM1_RS29530	COG4771	TonB-dependent receptor
AM1_RS29535	COG2223	nitrite transmembrane transporter activity
AM1_RS29540	COG1132	(ABC) transporter
AM1_RS29540	COG2375	cellular response to nickel ion
AM1_RS29545	COG1132	(ABC) transporter
AM1_RS29580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM1_RS29595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM1_RS29665	COG2119	membrane
AM1_RS29680	COG1132	(ABC) transporter
AM1_RS29735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM1_RS29750	COG0604	alcohol dehydrogenase
AM1_RS29750	COG3321	synthase
AM1_RS29750	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS29755	COG2226	methyltransferase
AM1_RS29755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM1_RS29755	COG3433	isochorismatase activity
AM1_RS29790	COG2226	methyltransferase
AM1_RS29855	COG1192	Involved in chromosome partitioning
AM1_RS29860	COG1475	DNA binding
AM1_RS29890	COG0582	viral genome integration into host DNA
AM1_RS29895	COG1484	DNA-dependent DNA replication
AM1_RS29900	COG4584	PFAM Integrase catalytic
AM1_RS29905	COG0582	viral genome integration into host DNA
AM1_RS29930	COG0735	belongs to the Fur family
AM1_RS29935	COG2119	membrane
AM1_RS29955	COG2814	Major facilitator Superfamily
AM1_RS29960	COG4774	siderophore transport
AM1_RS29975	COG0288	reversible hydration of carbon dioxide
AM1_RS30015	COG2994	toxin metabolic process
AM1_RS30040	COG1024	Enoyl-CoA hydratase
AM1_RS30040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM1_RS30045	COG2319	Wd-40 repeat
AM1_RS30045	COG3903	Transcriptional regulator
AM1_RS30055	COG0450	alkyl hydroperoxide reductase
AM1_RS30065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM1_RS30070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM1_RS30115	COG1475	DNA binding
AM1_RS30145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM1_RS30185	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM1_RS30275	COG0776	regulation of translation
AM1_RS30280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS30350	COG3328	transposase activity
AM1_RS30420	COG1484	DNA-dependent DNA replication
AM1_RS30425	COG4584	PFAM Integrase catalytic
AM1_RS30435	COG1484	DNA-dependent DNA replication
AM1_RS30450	COG4584	PFAM Integrase catalytic
AM1_RS30455	COG1484	DNA-dependent DNA replication
AM1_RS30515	COG1192	Involved in chromosome partitioning
AM1_RS30520	COG1475	DNA binding
AM1_RS30645	COG1960	acyl-CoA dehydrogenase activity
AM1_RS30750	COG0776	regulation of translation
AM1_RS30755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS30775	COG0823	Involved in the tonB-independent uptake of proteins
AM1_RS30845	COG0523	cobalamin synthesis protein
AM1_RS30860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM1_RS30865	COG0848	biopolymer transport protein
AM1_RS30870	COG0811	peptide transport
AM1_RS30875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM1_RS30880	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM1_RS30910	COG0625	glutathione transferase activity
AM1_RS30915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM1_RS30945	COG0735	belongs to the Fur family
AM1_RS30955	COG0523	cobalamin synthesis protein
AM1_RS30965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM1_RS30975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM1_RS30985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM1_RS30990	COG0640	Transcriptional regulator
AM1_RS31015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM1_RS31030	COG0215	cysteine-tRNA ligase activity
AM1_RS31035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM1_RS31055	COG0302	gtp cyclohydrolase
AM1_RS31065	COG4942	peptidase
AM1_RS31075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM1_RS31105	COG4974	Belongs to the 'phage' integrase family
AM1_RS31145	COG0582	viral genome integration into host DNA
AM1_RS31155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM1_RS31160	COG0572	uridine kinase
AM1_RS31205	COG3328	transposase activity
AM1_RS31440	COG0515	serine threonine protein kinase
AM1_RS31440	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM1_RS31445	COG0515	serine threonine protein kinase
AM1_RS31445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM1_RS31470	COG0515	serine threonine protein kinase
AM1_RS31470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM1_RS31590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS31605	COG2815	serine threonine protein kinase
AM1_RS31605	COG0515	serine threonine protein kinase
AM1_RS31630	COG2124	cytochrome p450
AM1_RS31635	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS31650	COG3903	Transcriptional regulator
AM1_RS31650	COG2319	Wd-40 repeat
AM1_RS31665	COG1525	nuclease
AM1_RS31675	COG3422	double-strand break repair
AM1_RS31685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM1_RS31700	COG2319	Wd-40 repeat
AM1_RS31700	COG5635	Nacht domain
AM1_RS31705	COG0582	viral genome integration into host DNA
AM1_RS31745	COG4974	Belongs to the 'phage' integrase family
AM1_RS31880	COG1525	nuclease
AM1_RS31885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM1_RS31915	COG3093	addiction module antidote protein HigA
AM1_RS31930	COG1484	DNA-dependent DNA replication
AM1_RS31935	COG4584	PFAM Integrase catalytic
AM1_RS31945	COG3547	Transposase (IS116 IS110 IS902 family)
AM1_RS31980	COG2319	Wd-40 repeat
AM1_RS31980	COG3903	Transcriptional regulator
AM1_RS32010	COG3547	Transposase (IS116 IS110 IS902 family)
AM1_RS32020	COG1662	PFAM IS1 transposase
AM1_RS32035	COG1799	cell septum assembly
AM1_RS32045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM1_RS32050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM1_RS32130	COG2198	Histidine kinase
AM1_RS32130	COG0784	Response regulator, receiver
AM1_RS32130	COG2205	protein histidine kinase activity
AM1_RS32140	COG4585	Histidine kinase
AM1_RS32145	COG2197	response regulator
AM1_RS32150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM1_RS32170	COG0784	Response regulator, receiver
AM1_RS32170	COG2198	Histidine kinase
AM1_RS32170	COG5002	protein histidine kinase activity
AM1_RS32280	COG0724	RNA recognition motif
AM1_RS32285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM1_RS32295	COG0583	DNA-binding transcription factor activity
AM1_RS32310	COG0583	DNA-binding transcription factor activity
AM1_RS32325	COG1309	transcriptional regulator
AM1_RS32365	COG1484	DNA-dependent DNA replication
AM1_RS32370	COG4584	PFAM Integrase catalytic
AM1_RS32385	COG0724	RNA recognition motif
AM1_RS32400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM1_RS32405	COG4584	PFAM Integrase catalytic
AM1_RS32410	COG1484	DNA-dependent DNA replication
AM1_RS32430	COG2045	Belongs to the ComB family
AM1_RS32435	COG0745	RESPONSE REGULATOR receiver
AM1_RS32455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM1_RS32495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM1_RS32505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM1_RS32510	COG5398	heme oxygenase
AM1_RS32605	COG0582	viral genome integration into host DNA
AM1_RS32755	COG1012	belongs to the aldehyde dehydrogenase family
AM1_RS32835	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM1_RS32840	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM1_RS32845	COG5398	heme oxygenase
AM1_RS33040	COG0596	Alpha beta hydrolase
AM1_RS33070	COG1413	lyase activity
AM1_RS33130	COG1192	Involved in chromosome partitioning
AM1_RS33135	COG1475	DNA binding
AM1_RS33170	COG1216	Glycosyl transferase, family 2
AM1_RS33205	COG0745	RESPONSE REGULATOR receiver
AM1_RS33210	COG5002	protein histidine kinase activity
AM1_RS33315	COG0776	regulation of translation
AM1_RS33320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS33330	COG2318	DinB family
AM1_RS33365	COG0776	regulation of translation
AM1_RS33470	COG0724	RNA recognition motif
AM1_RS33500	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM1_RS33510	COG0745	RESPONSE REGULATOR receiver
AM1_RS33580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS33690	COG1484	DNA-dependent DNA replication
AM1_RS33760	COG1662	PFAM IS1 transposase
AM1_RS33795	COG0322	excinuclease ABC activity
AM1_RS33805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM1_RS33810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS33860	COG3657	addiction module killer protein
AM1_RS33925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM1_RS33950	COG1192	Involved in chromosome partitioning
AM1_RS34000	COG0205	6-phosphofructokinase activity
AM1_RS34005	COG0409	Hydrogenase expression formation protein
AM1_RS34010	COG0071	Belongs to the small heat shock protein (HSP20) family
AM1_RS34020	COG1136	(ABC) transporter
AM1_RS34050	COG0574	Belongs to the PEP-utilizing enzyme family
AM1_RS34050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM1_RS34070	COG0475	glutathione-regulated potassium exporter activity
AM1_RS34100	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM1_RS34125	COG0726	polysaccharide deacetylase
AM1_RS34130	COG0589	response to stress
AM1_RS34135	COG0778	Nitroreductase
AM1_RS34140	COG0589	response to stress
AM1_RS34175	COG1034	ATP synthesis coupled electron transport
AM1_RS34180	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM1_RS34185	COG0517	IMP dehydrogenase activity
AM1_RS34200	COG3259	Nickel-dependent hydrogenase
AM1_RS34205	COG0298	carbon dioxide binding
AM1_RS34210	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM1_RS34225	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM1_RS34230	COG0375	protein maturation
AM1_RS34250	COG0309	Hydrogenase expression formation protein (HypE)
AM1_RS34260	COG0058	SHG alpha-glucan phosphorylase activity
AM1_RS34265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS34285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM1_RS34325	COG4974	Belongs to the 'phage' integrase family
AM1_RS34365	COG4584	PFAM Integrase catalytic
AM1_RS34370	COG1484	DNA-dependent DNA replication
AM1_RS34380	COG0589	response to stress
AM1_RS34395	COG0702	epimerase
AM1_RS34420	COG2226	methyltransferase
AM1_RS34430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM1_RS34470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM1_RS34480	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM1_RS34480	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM1_RS34480	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM1_RS34480	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AM1_RS34485	COG0582	viral genome integration into host DNA
AM1_RS34505	COG1902	pentaerythritol trinitrate reductase activity
AM1_RS34535	COG0724	RNA recognition motif
AM1_RS34550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM1_RS34620	COG0582	viral genome integration into host DNA
AM1_RS34845	COG4584	PFAM Integrase catalytic
AM1_RS34850	COG1484	DNA-dependent DNA replication
AM1_RS34860	COG1484	DNA-dependent DNA replication
AM1_RS34905	COG1192	Involved in chromosome partitioning
AM1_RS34925	COG0557	exoribonuclease II activity
AM1_RS34945	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS34950	COG1733	regulation of RNA biosynthetic process
AM1_RS34975	COG3903	Transcriptional regulator
AM1_RS34975	COG2319	Wd-40 repeat
AM1_RS34980	COG4974	Belongs to the 'phage' integrase family
AM1_RS35025	COG3214	Protein conserved in bacteria
AM1_RS35040	COG0557	exoribonuclease II activity
AM1_RS35050	COG3422	double-strand break repair
AM1_RS35225	COG1484	DNA-dependent DNA replication
AM1_RS35230	COG4584	PFAM Integrase catalytic
AM1_RS35390	COG1595	DNA-templated transcription, initiation
AM1_RS35395	COG2161	toxin-antitoxin pair type II binding
AM1_RS35415	COG4804	nuclease activity
AM1_RS35485	COG2340	Cysteine-rich secretory protein family
AM1_RS35555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM1_RS35565	COG1192	Involved in chromosome partitioning
AM1_RS35575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM1_RS35585	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM1_RS35590	COG0583	DNA-binding transcription factor activity
AM1_RS35630	COG0640	Transcriptional regulator
AM1_RS35635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM1_RS35645	COG5433	transposase activity
AM1_RS35700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM1_RS35710	COG0523	cobalamin synthesis protein
AM1_RS35720	COG0735	belongs to the Fur family
AM1_RS35730	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM1_RS35760	COG0515	serine threonine protein kinase
AM1_RS35760	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS35790	COG1902	pentaerythritol trinitrate reductase activity
AM1_RS35800	COG0501	Belongs to the peptidase M48B family
AM1_RS35805	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM1_RS35835	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM1_RS35845	COG0745	RESPONSE REGULATOR receiver
AM1_RS35900	COG0515	serine threonine protein kinase
AM1_RS35900	COG2815	serine threonine protein kinase
AM1_RS35905	COG2319	Wd-40 repeat
AM1_RS35905	COG3903	Transcriptional regulator
AM1_RS36015	COG4584	PFAM Integrase catalytic
AM1_RS36020	COG1484	DNA-dependent DNA replication
AM1_RS36110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM1_RS36135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS36240	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM1_RS36245	COG2319	Wd-40 repeat
AM1_RS36280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM1_RS36285	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM1_RS36290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM1_RS36305	COG1192	Involved in chromosome partitioning
AM1_RS36360	COG0004	ammonium transporteR
AM1_RS36385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM1_RS36405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS36485	COG0739	heme binding
AM1_RS36510	COG1028	Short-chain dehydrogenase reductase Sdr
AM1_RS36530	COG0300	oxidoreductase activity
AM1_RS36535	COG0300	oxidoreductase activity
AM1_RS36575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM1_RS36625	COG0515	serine threonine protein kinase
AM1_RS36625	COG1357	PFAM Pentapeptide repeats (8 copies)
AM1_RS36635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM1_RS36650	COG4584	PFAM Integrase catalytic
AM1_RS36655	COG1484	DNA-dependent DNA replication
AM1_RS36680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM1_RS36825	COG4249	Peptidase C14 caspase catalytic subunit p20
AM1_RS36825	COG2319	Wd-40 repeat
AM1_RS36825	COG2319	Wd-40 repeat
AM1_RS36825	COG4249	Peptidase C14 caspase catalytic subunit p20
AM1_RS36840	COG3903	Transcriptional regulator
AM1_RS36840	COG2319	Wd-40 repeat
AM1_RS36875	COG1484	DNA-dependent DNA replication
AM1_RS37090	COG3063	Type IV pilus biogenesis stability protein PilW
AM1_RS37095	COG5001	Diguanylate cyclase
AM1_RS37095	COG4251	negative regulation of phosphorylation
AM1_RS37095	COG3706	GGDEF domain
AM1_RS37095	COG2203	Gaf domain
AM1_RS37100	COG4974	Belongs to the 'phage' integrase family
AM1_RS37105	COG4249	Peptidase C14 caspase catalytic subunit p20
AM1_RS37105	COG2319	Wd-40 repeat
AM1_RS37125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM1_RS37145	COG4581	dead DEAH box helicase
AM1_RS37170	COG1192	Involved in chromosome partitioning
AM1_RS37175	COG4584	PFAM Integrase catalytic
AM1_RS37180	COG1484	DNA-dependent DNA replication
AM1_RS37250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM1_RS37315	COG0739	heme binding
AM1_RS37410	COG0784	Response regulator, receiver
AM1_RS37410	COG5002	protein histidine kinase activity
AM1_RS37420	COG2223	nitrite transmembrane transporter activity
AM1_RS37440	COG2204	response regulator
AM1_RS37445	COG4251	negative regulation of phosphorylation
AM1_RS37465	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM1_RS37485	COG2205	protein histidine kinase activity
AM1_RS37485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM1_RS37490	COG2205	protein histidine kinase activity
AM1_RS37490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM1_RS37495	COG2319	Wd-40 repeat
AM1_RS37495	COG5635	Nacht domain
AM1_RS37540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM1_RS37540	COG4191	Histidine kinase
AM1_RS37560	COG0732	type I restriction modification DNA specificity domain
AM1_RS37615	COG0584	glycerophosphoryl diester phosphodiesterase
AM1_RS37625	COG0515	serine threonine protein kinase
AM1_RS37625	COG3266	domain, Protein
AM1_RS37635	COG5002	protein histidine kinase activity
AM1_RS37645	COG2720	vancomycin resistance protein
AM1_RS37655	COG4251	negative regulation of phosphorylation
AM1_RS37685	COG1051	belongs to the nudix hydrolase family
AM1_RS37705	COG2197	response regulator
AM1_RS37715	COG0745	RESPONSE REGULATOR receiver
AM1_RS37740	COG3300	MHYT domain
AM1_RS37740	COG5001	Diguanylate cyclase
AM1_RS37785	COG0784	Response regulator, receiver
AM1_RS37785	COG2205	protein histidine kinase activity
AM1_RS37795	COG0515	serine threonine protein kinase
AM1_RS37795	COG3266	domain, Protein
AM1_RS37840	COG0784	Response regulator, receiver
AM1_RS37840	COG5002	protein histidine kinase activity
AM1_RS37940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM1_RS37965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM1_RS37965	COG0515	serine threonine protein kinase
AM1_RS37975	COG0739	heme binding
AM1_RS38010	COG0657	acetylesterase activity
AM1_RS38055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM1_RS38075	COG0739	heme binding
AM1_RS38120	COG0739	heme binding