locus-tag	class	description
AAJCM20276_RS00040	COG0318	PFAM AMP-dependent synthetase and ligase
AAJCM20276_RS00045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAJCM20276_RS00050	COG0156	8-amino-7-oxononanoate synthase activity
AAJCM20276_RS00055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_RS00105	COG3093	addiction module antidote protein HigA
AAJCM20276_RS00150	COG0582	viral genome integration into host DNA
AAJCM20276_RS00155	COG0519	Catalyzes the synthesis of GMP from XMP
AAJCM20276_RS00155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AAJCM20276_RS00175	COG3293	Transposase
AAJCM20276_RS00180	COG0246	Mannitol dehydrogenase
AAJCM20276_RS00190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAJCM20276_RS00255	COG1881	PFAM PEBP family protein
AAJCM20276_RS00265	COG1278	Cold shock
AAJCM20276_RS00285	COG1271	oxidase subunit
AAJCM20276_RS00290	COG1294	oxidase, subunit
AAJCM20276_RS00320	COG1393	Belongs to the ArsC family
AAJCM20276_RS00325	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_RS00330	COG4993	Dehydrogenase
AAJCM20276_RS00350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AAJCM20276_RS00360	COG0488	(ABC) transporter
AAJCM20276_RS00370	COG2091	lysine biosynthetic process via aminoadipic acid
AAJCM20276_RS00385	COG2814	Major facilitator Superfamily
AAJCM20276_RS00390	COG1566	PFAM secretion protein HlyD family protein
AAJCM20276_RS00425	COG0431	NADPH-dependent FMN reductase
AAJCM20276_RS00440	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AAJCM20276_RS00455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AAJCM20276_RS00480	COG0859	PFAM glycosyl transferase family 9
AAJCM20276_RS00485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AAJCM20276_RS00490	COG1959	2 iron, 2 sulfur cluster binding
AAJCM20276_RS00495	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AAJCM20276_RS00500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAJCM20276_RS00505	COG1120	ATPase activity
AAJCM20276_RS00525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AAJCM20276_RS00530	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AAJCM20276_RS00535	COG1104	cysteine desulfurase activity
AAJCM20276_RS00545	COG0482	sulfurtransferase activity
AAJCM20276_RS00565	COG1505	serine-type exopeptidase activity
AAJCM20276_RS00570	COG0582	viral genome integration into host DNA
AAJCM20276_RS00575	COG3311	Transcriptional regulator
AAJCM20276_RS00580	COG1569	PIN domain
AAJCM20276_RS00640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AAJCM20276_RS00650	COG0424	maF-like protein
AAJCM20276_RS00655	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AAJCM20276_RS00660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AAJCM20276_RS00665	COG1981	membrane
AAJCM20276_RS00700	COG2814	Major facilitator Superfamily
AAJCM20276_RS00710	COG0436	Aminotransferase
AAJCM20276_RS00715	COG1914	H( )-stimulated, divalent metal cation uptake system
AAJCM20276_RS00720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAJCM20276_RS00760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AAJCM20276_RS00765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AAJCM20276_RS00795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AAJCM20276_RS00865	COG0357	Ribosomal RNA small subunit methyltransferase G
AAJCM20276_RS00870	COG0445	tRNA wobble uridine modification
AAJCM20276_RS00875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AAJCM20276_RS00880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AAJCM20276_RS00905	COG4232	protein-disulfide reductase activity
AAJCM20276_RS00910	COG1643	Atp-dependent helicase
AAJCM20276_RS00920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AAJCM20276_RS00925	COG2205	protein histidine kinase activity
AAJCM20276_RS00930	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_RS00940	COG0443	Heat shock 70 kDa protein
AAJCM20276_RS00945	COG0484	heat shock protein binding
AAJCM20276_RS00970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAJCM20276_RS00975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AAJCM20276_RS00995	COG0702	epimerase
AAJCM20276_RS01000	COG1733	regulation of RNA biosynthetic process
AAJCM20276_RS01015	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AAJCM20276_RS01020	COG0343	queuine tRNA-ribosyltransferase activity
AAJCM20276_RS01040	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AAJCM20276_RS01045	COG0596	Alpha beta hydrolase
AAJCM20276_RS01045	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAJCM20276_RS01050	COG0022	dehydrogenase e1 component
AAJCM20276_RS01055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AAJCM20276_RS01065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AAJCM20276_RS01070	COG0805	protein transport
AAJCM20276_RS01075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAJCM20276_RS01105	COG0297	glycogen (starch) synthase activity
AAJCM20276_RS01125	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AAJCM20276_RS01130	COG1660	Displays ATPase and GTPase activities
AAJCM20276_RS01140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAJCM20276_RS01145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AAJCM20276_RS01155	COG0408	coproporphyrinogen oxidase activity
AAJCM20276_RS01160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AAJCM20276_RS01175	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AAJCM20276_RS01205	COG0402	S-adenosylhomocysteine deaminase activity
AAJCM20276_RS01240	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAJCM20276_RS01250	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AAJCM20276_RS01255	COG1138	Cytochrome C-type biogenesis protein
AAJCM20276_RS01260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAJCM20276_RS01265	COG3088	subunit of a heme lyase
AAJCM20276_RS01275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAJCM20276_RS01280	COG2813	Specifically methylates the guanine in position
AAJCM20276_RS01280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAJCM20276_RS01290	COG0513	Belongs to the DEAD box helicase family
AAJCM20276_RS01310	COG1959	2 iron, 2 sulfur cluster binding
AAJCM20276_RS01325	COG3128	pkhd-type hydroxylase
AAJCM20276_RS01350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AAJCM20276_RS01355	COG2070	2-Nitropropane dioxygenase
AAJCM20276_RS01365	COG0129	dihydroxy-acid dehydratase activity
AAJCM20276_RS01370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AAJCM20276_RS01380	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS01385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAJCM20276_RS01410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAJCM20276_RS01425	COG1742	UPF0060 membrane protein
AAJCM20276_RS01430	COG0602	queuosine metabolic process
AAJCM20276_RS01435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AAJCM20276_RS01465	COG0284	orotidine-5'-phosphate decarboxylase activity
AAJCM20276_RS01470	COG0135	phosphoribosylanthranilate isomerase activity
AAJCM20276_RS01480	COG0582	viral genome integration into host DNA
AAJCM20276_RS01495	COG0210	DNA helicase
AAJCM20276_RS01520	COG0210	DNA helicase
AAJCM20276_RS01535	COG2072	flavoprotein involved in K transport
AAJCM20276_RS01540	COG0431	NADPH-dependent FMN reductase
AAJCM20276_RS01580	COG1959	2 iron, 2 sulfur cluster binding
AAJCM20276_RS01590	COG3256	nitric oxide reductase
AAJCM20276_RS01595	COG3189	MarR family transcriptional regulator
AAJCM20276_RS01645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AAJCM20276_RS01680	COG5489	Protein of unknown function (DUF736)
AAJCM20276_RS01685	COG1476	TRANSCRIPTIONal
AAJCM20276_RS01730	COG0741	lytic transglycosylase activity
AAJCM20276_RS01765	COG4962	Type ii secretion system protein e
AAJCM20276_RS01780	COG3451	type IV secretory pathway VirB4
AAJCM20276_RS01815	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS01845	COG0625	glutathione transferase activity
AAJCM20276_RS01865	COG0596	Alpha beta hydrolase
AAJCM20276_RS01870	COG2226	methyltransferase
AAJCM20276_RS01950	COG0450	alkyl hydroperoxide reductase
AAJCM20276_RS01960	COG4988	ABC transporter
AAJCM20276_RS01965	COG1132	(ABC) transporter
AAJCM20276_RS01970	COG1271	oxidase subunit
AAJCM20276_RS01975	COG1294	oxidase, subunit
AAJCM20276_RS02000	COG3290	protein histidine kinase activity
AAJCM20276_RS02010	COG1595	DNA-templated transcription, initiation
AAJCM20276_RS02035	COG2801	Transposase and inactivated derivatives
AAJCM20276_RS02060	COG3547	Transposase (IS116 IS110 IS902 family)
AAJCM20276_RS02160	COG2271	Major facilitator Superfamily
AAJCM20276_RS02175	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS02225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAJCM20276_RS02290	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AAJCM20276_RS02295	COG0587	DNA-directed DNA polymerase activity
AAJCM20276_RS02310	COG0210	DNA helicase
AAJCM20276_RS02325	COG1201	RNA secondary structure unwinding
AAJCM20276_RS02445	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AAJCM20276_RS02570	COG2963	transposase activity
AAJCM20276_RS02625	COG0564	pseudouridine synthase activity
AAJCM20276_RS02635	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AAJCM20276_RS02640	COG0667	Aldo Keto reductase
AAJCM20276_RS02645	COG1420	regulation of RNA biosynthetic process
AAJCM20276_RS02675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AAJCM20276_RS02695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AAJCM20276_RS02700	COG0351	phosphomethylpyrimidine kinase
AAJCM20276_RS02700	COG0352	thiamine-phosphate diphosphorylase activity
AAJCM20276_RS02720	COG0802	atpase or kinase
AAJCM20276_RS02725	COG2887	Belongs to the helicase family. UvrD subfamily
AAJCM20276_RS02730	COG1074	ATP-dependent DNA helicase activity
AAJCM20276_RS02755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AAJCM20276_RS02760	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AAJCM20276_RS02770	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAJCM20276_RS02775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAJCM20276_RS02795	COG2875	Belongs to the precorrin methyltransferase family
AAJCM20276_RS02810	COG2099	Precorrin-6x reductase
AAJCM20276_RS02840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AAJCM20276_RS02865	COG0560	Phosphoserine phosphatase
AAJCM20276_RS02865	COG3830	Belongs to the UPF0237 family
AAJCM20276_RS02870	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AAJCM20276_RS02875	COG0028	Belongs to the TPP enzyme family
AAJCM20276_RS02890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AAJCM20276_RS02895	COG3293	Transposase
AAJCM20276_RS02905	COG2963	transposase activity
AAJCM20276_RS02910	COG3436	PFAM IS66 Orf2 family protein
AAJCM20276_RS02955	COG0436	Aminotransferase
AAJCM20276_RS02970	COG0511	ligase activity, forming carbon-carbon bonds
AAJCM20276_RS02975	COG4221	oxidoreductase activity
AAJCM20276_RS02980	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AAJCM20276_RS02985	COG1984	allophanate hydrolase subunit 2
AAJCM20276_RS02990	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AAJCM20276_RS02995	COG0697	spore germination
AAJCM20276_RS03000	COG2271	Major facilitator Superfamily
AAJCM20276_RS03040	COG0133	tryptophan synthase activity
AAJCM20276_RS03045	COG0159	tryptophan synthase activity
AAJCM20276_RS03050	COG0484	heat shock protein binding
AAJCM20276_RS03205	COG2983	Belongs to the UPF0260 family
AAJCM20276_RS03250	COG0492	ferredoxin-NADP+ reductase activity
AAJCM20276_RS03255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AAJCM20276_RS03270	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AAJCM20276_RS03270	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AAJCM20276_RS03270	COG0506	proline dehydrogenase activity
AAJCM20276_RS03275	COG0655	NAD(P)H dehydrogenase (quinone) activity
AAJCM20276_RS03280	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS03295	COG0307	riboflavin synthase, alpha
AAJCM20276_RS03300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AAJCM20276_RS03300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AAJCM20276_RS03305	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AAJCM20276_RS03315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAJCM20276_RS03320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AAJCM20276_RS03365	COG3293	Transposase
AAJCM20276_RS03380	COG1252	NADH dehydrogenase
AAJCM20276_RS03400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAJCM20276_RS03400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAJCM20276_RS03405	COG0509	glycine decarboxylation via glycine cleavage system
AAJCM20276_RS03410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AAJCM20276_RS03415	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AAJCM20276_RS03420	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AAJCM20276_RS03440	COG0776	regulation of translation
AAJCM20276_RS03475	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AAJCM20276_RS03495	COG2096	Adenosyltransferase
AAJCM20276_RS03520	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AAJCM20276_RS03530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AAJCM20276_RS03555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AAJCM20276_RS03560	COG1758	RNA polymerase activity
AAJCM20276_RS03565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AAJCM20276_RS03570	COG0736	holo-[acyl-carrier-protein] synthase activity
AAJCM20276_RS03575	COG0681	Belongs to the peptidase S26 family
AAJCM20276_RS03580	COG0571	ribonuclease III activity
AAJCM20276_RS03585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AAJCM20276_RS03590	COG0528	UMP kinase activity
AAJCM20276_RS03595	COG0233	cytoplasmic translational termination
AAJCM20276_RS03600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AAJCM20276_RS03605	COG0575	Belongs to the CDS family
AAJCM20276_RS03610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AAJCM20276_RS03615	COG0750	zinc metalloprotease
AAJCM20276_RS03620	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAJCM20276_RS03630	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAJCM20276_RS03635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AAJCM20276_RS03640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAJCM20276_RS03645	COG3494	Protein of unknown function (DUF1009)
AAJCM20276_RS03665	COG0346	lactoylglutathione lyase activity
AAJCM20276_RS03675	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AAJCM20276_RS03680	COG0594	ribonuclease P activity
AAJCM20276_RS03685	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AAJCM20276_RS03690	COG0706	membrane insertase activity
AAJCM20276_RS03695	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AAJCM20276_RS03700	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AAJCM20276_RS03715	COG0670	Belongs to the BI1 family
AAJCM20276_RS03735	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AAJCM20276_RS03755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AAJCM20276_RS03770	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AAJCM20276_RS03780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AAJCM20276_RS03800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AAJCM20276_RS03825	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AAJCM20276_RS03830	COG1396	sequence-specific DNA binding
AAJCM20276_RS03840	COG0629	single-stranded DNA binding
AAJCM20276_RS03845	COG2010	Cytochrome c
AAJCM20276_RS03845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AAJCM20276_RS03860	COG0326	Molecular chaperone. Has ATPase activity
AAJCM20276_RS03870	COG0488	(ABC) transporter
AAJCM20276_RS03875	COG0784	Response regulator, receiver
AAJCM20276_RS03925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAJCM20276_RS03945	COG1271	oxidase subunit
AAJCM20276_RS03950	COG1294	oxidase, subunit
AAJCM20276_RS03965	COG0243	molybdopterin cofactor binding
AAJCM20276_RS03970	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AAJCM20276_RS03975	COG0746	molybdenum cofactor guanylyltransferase activity
AAJCM20276_RS03975	COG0315	cyclic pyranopterin monophosphate synthase activity
AAJCM20276_RS03985	COG0314	molybdopterin synthase activity
AAJCM20276_RS03990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AAJCM20276_RS04025	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AAJCM20276_RS04035	COG4786	Flagellar basal body rod
AAJCM20276_RS04040	COG4786	Flagellar basal body rod
AAJCM20276_RS04050	COG0778	Nitroreductase
AAJCM20276_RS04055	COG0477	Major facilitator Superfamily
AAJCM20276_RS04085	COG1322	Protein conserved in bacteria
AAJCM20276_RS04090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAJCM20276_RS04115	COG1877	trehalose-phosphatase activity
AAJCM20276_RS04120	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AAJCM20276_RS04140	COG0542	response to heat
AAJCM20276_RS04165	COG3038	cytochrome b561
AAJCM20276_RS04185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AAJCM20276_RS04205	COG2072	flavoprotein involved in K transport
AAJCM20276_RS04230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAJCM20276_RS04235	COG1116	anion transmembrane transporter activity
AAJCM20276_RS04240	COG0864	Transcriptional regulator
AAJCM20276_RS04250	COG3665	Urea carboxylase-associated protein
AAJCM20276_RS04270	COG2072	flavoprotein involved in K transport
AAJCM20276_RS04285	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAJCM20276_RS04295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AAJCM20276_RS04305	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS04310	COG1126	abc transporter atp-binding protein
AAJCM20276_RS04355	COG0538	isocitrate dehydrogenase activity
AAJCM20276_RS04375	COG0328	RNA-DNA hybrid ribonuclease activity
AAJCM20276_RS04380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AAJCM20276_RS04385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AAJCM20276_RS04395	COG0405	Gamma-glutamyltransferase
AAJCM20276_RS04425	COG3956	TIGRFAM MazG family protein
AAJCM20276_RS04435	COG1733	regulation of RNA biosynthetic process
AAJCM20276_RS04465	COG2207	Transcriptional regulator
AAJCM20276_RS04470	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_RS04475	COG3118	belongs to the thioredoxin family
AAJCM20276_RS04480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AAJCM20276_RS04485	COG2835	tetraacyldisaccharide 4'-kinase activity
AAJCM20276_RS04495	COG1032	radical SAM domain protein
AAJCM20276_RS04530	COG1596	polysaccharide export
AAJCM20276_RS04535	COG3750	Belongs to the UPF0335 family
AAJCM20276_RS04540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AAJCM20276_RS04555	COG0406	alpha-ribazole phosphatase activity
AAJCM20276_RS04560	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AAJCM20276_RS04565	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AAJCM20276_RS04600	COG4988	ABC transporter
AAJCM20276_RS04605	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AAJCM20276_RS04615	COG0514	ATP-dependent DNA helicase (RecQ)
AAJCM20276_RS04635	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AAJCM20276_RS04645	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_RS04660	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_RS04670	COG5002	protein histidine kinase activity
AAJCM20276_RS04725	COG2175	clavaminate synthase activity
AAJCM20276_RS04730	COG1113	amino acid transport
AAJCM20276_RS04740	COG2963	transposase activity
AAJCM20276_RS04750	COG1116	anion transmembrane transporter activity
AAJCM20276_RS04755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAJCM20276_RS04785	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS04795	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS04810	COG2132	Multicopper oxidase
AAJCM20276_RS04815	COG2814	Major facilitator Superfamily
AAJCM20276_RS04885	COG0740	serine-type endopeptidase activity
AAJCM20276_RS04900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AAJCM20276_RS04905	COG1766	The M ring may be actively involved in energy transduction
AAJCM20276_RS04910	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AAJCM20276_RS04920	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AAJCM20276_RS04925	COG2204	response regulator
AAJCM20276_RS04930	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AAJCM20276_RS04940	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AAJCM20276_RS04950	COG3293	Transposase
AAJCM20276_RS04960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AAJCM20276_RS04965	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AAJCM20276_RS04970	COG1137	ATPase activity
AAJCM20276_RS05025	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AAJCM20276_RS05060	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AAJCM20276_RS05065	COG1335	isochorismatase
AAJCM20276_RS05070	COG1744	ABC transporter substrate-binding protein PnrA-like
AAJCM20276_RS05075	COG3845	ABC transporter
AAJCM20276_RS05085	COG1079	Belongs to the binding-protein-dependent transport system permease family
AAJCM20276_RS05095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAJCM20276_RS05095	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AAJCM20276_RS05100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAJCM20276_RS05100	COG1372	Participates in initiation and elongation during chromosome replication
AAJCM20276_RS05110	COG2244	polysaccharide biosynthetic process
AAJCM20276_RS05125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AAJCM20276_RS05135	COG2351	hydroxyisourate hydrolase activity
AAJCM20276_RS05150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AAJCM20276_RS05180	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS05200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAJCM20276_RS05205	COG0402	S-adenosylhomocysteine deaminase activity
AAJCM20276_RS05270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAJCM20276_RS05280	COG0181	hydroxymethylbilane synthase activity
AAJCM20276_RS05285	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AAJCM20276_RS05315	COG0004	ammonium transporteR
AAJCM20276_RS05340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_RS05345	COG0840	transmembrane signaling receptor activity
AAJCM20276_RS05355	COG0643	Histidine kinase
AAJCM20276_RS05355	COG2198	Histidine kinase
AAJCM20276_RS05360	COG0835	chemotaxis
AAJCM20276_RS05365	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AAJCM20276_RS05370	COG2201	protein-glutamate methylesterase activity
AAJCM20276_RS05375	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_RS05380	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AAJCM20276_RS05390	COG0488	(ABC) transporter
AAJCM20276_RS05395	COG0105	UTP biosynthetic process
AAJCM20276_RS05415	COG2706	6-phosphogluconolactonase activity
AAJCM20276_RS05420	COG0281	malic enzyme
AAJCM20276_RS05430	COG0215	cysteine-tRNA ligase activity
AAJCM20276_RS05450	COG5492	domain, Protein
AAJCM20276_RS05450	COG3583	domain protein
AAJCM20276_RS05450	COG1621	beta-fructofuranosidase activity
AAJCM20276_RS05475	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAJCM20276_RS05475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AAJCM20276_RS05485	COG1760	l-serine dehydratase
AAJCM20276_RS05490	COG4638	Rieske (2fe-2S)
AAJCM20276_RS05505	COG1902	pentaerythritol trinitrate reductase activity
AAJCM20276_RS05505	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAJCM20276_RS05510	COG0247	lactate metabolic process
AAJCM20276_RS05510	COG2181	nitrate reductase activity
AAJCM20276_RS05525	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AAJCM20276_RS05530	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AAJCM20276_RS05555	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS05590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AAJCM20276_RS05595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAJCM20276_RS05595	COG3153	acetyltransferase
AAJCM20276_RS05610	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_RS05620	COG0675	Transposase, IS605 OrfB family
AAJCM20276_RS05630	COG4175	Glycine betaine
AAJCM20276_RS05670	COG1113	amino acid transport
AAJCM20276_RS05675	COG3588	fructose-bisphosphate aldolase
AAJCM20276_RS05680	COG3961	Belongs to the TPP enzyme family
AAJCM20276_RS05685	COG0247	lactate metabolic process
AAJCM20276_RS05690	COG1139	Iron-sulfur cluster binding protein
AAJCM20276_RS05725	COG0052	Belongs to the universal ribosomal protein uS2 family
AAJCM20276_RS05730	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AAJCM20276_RS05735	COG1381	Involved in DNA repair and RecF pathway recombination
AAJCM20276_RS05750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAJCM20276_RS05775	COG3261	NADH dehydrogenase
AAJCM20276_RS05775	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AAJCM20276_RS05780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_RS05785	COG1183	phosphatidylcholine synthase activity
AAJCM20276_RS05790	COG0688	phosphatidylethanolamine metabolic process
AAJCM20276_RS05810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAJCM20276_RS05835	COG2884	Cell division ATP-binding protein ftsE
AAJCM20276_RS05855	COG2081	HI0933 family
AAJCM20276_RS05860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AAJCM20276_RS05865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AAJCM20276_RS05875	COG0628	permease
AAJCM20276_RS05950	COG0667	Aldo Keto reductase
AAJCM20276_RS05965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AAJCM20276_RS05970	COG0778	Nitroreductase
AAJCM20276_RS05980	COG5564	TIM-barrel signal transduction protein
AAJCM20276_RS05985	COG5441	Belongs to the UPF0261 family
AAJCM20276_RS05995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AAJCM20276_RS06010	COG2837	iron assimilation
AAJCM20276_RS06015	COG2814	Major facilitator Superfamily
AAJCM20276_RS06045	COG0101	tRNA pseudouridine synthase activity
AAJCM20276_RS06050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AAJCM20276_RS06055	COG0242	peptide deformylase activity
AAJCM20276_RS06075	COG3145	DNA-N1-methyladenine dioxygenase activity
AAJCM20276_RS06095	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AAJCM20276_RS06125	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AAJCM20276_RS06140	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AAJCM20276_RS06145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AAJCM20276_RS06145	COG0574	Belongs to the PEP-utilizing enzyme family
AAJCM20276_RS06150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AAJCM20276_RS06155	COG0497	DNA recombination
AAJCM20276_RS06160	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAJCM20276_RS06175	COG0849	cell division
AAJCM20276_RS06180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AAJCM20276_RS06185	COG1181	Belongs to the D-alanine--D-alanine ligase family
AAJCM20276_RS06190	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AAJCM20276_RS06195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AAJCM20276_RS06200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AAJCM20276_RS06210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AAJCM20276_RS06215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AAJCM20276_RS06220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AAJCM20276_RS06225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AAJCM20276_RS06240	COG0275	rRNA processing
AAJCM20276_RS06245	COG2001	Belongs to the MraZ family
AAJCM20276_RS06255	COG0657	acetylesterase activity
AAJCM20276_RS06265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAJCM20276_RS06270	COG4774	siderophore transport
AAJCM20276_RS06280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AAJCM20276_RS06285	COG0110	maltose O-acetyltransferase activity
AAJCM20276_RS06290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AAJCM20276_RS06295	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AAJCM20276_RS06305	COG0047	phosphoribosylformylglycinamidine synthase activity
AAJCM20276_RS06310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AAJCM20276_RS06315	COG0271	Belongs to the BolA IbaG family
AAJCM20276_RS06320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AAJCM20276_RS06330	COG0792	nuclease activity
AAJCM20276_RS06335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAJCM20276_RS06340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AAJCM20276_RS06345	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AAJCM20276_RS06350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AAJCM20276_RS06355	COG3541	Predicted nucleotidyltransferase
AAJCM20276_RS06365	COG0138	bifunctional purine biosynthesis protein purh
AAJCM20276_RS06370	COG0439	Biotin carboxylase
AAJCM20276_RS06375	COG0511	ligase activity, forming carbon-carbon bonds
AAJCM20276_RS06380	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AAJCM20276_RS06395	COG1295	ribonuclease BN
AAJCM20276_RS06405	COG0521	Mo-molybdopterin cofactor biosynthetic process
AAJCM20276_RS06445	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AAJCM20276_RS06465	COG2205	protein histidine kinase activity
AAJCM20276_RS06475	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AAJCM20276_RS06485	COG0113	porphobilinogen synthase activity
AAJCM20276_RS06500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAJCM20276_RS06525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAJCM20276_RS06530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AAJCM20276_RS06530	COG2010	Cytochrome c
AAJCM20276_RS06545	COG0477	Major facilitator Superfamily
AAJCM20276_RS06555	COG0723	plastoquinol--plastocyanin reductase activity
AAJCM20276_RS06580	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AAJCM20276_RS06590	COG0424	maF-like protein
AAJCM20276_RS06595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AAJCM20276_RS06600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AAJCM20276_RS06605	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AAJCM20276_RS06625	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AAJCM20276_RS06630	COG3158	transport of potassium into the cell
AAJCM20276_RS06635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AAJCM20276_RS06665	COG1054	Belongs to the UPF0176 family
AAJCM20276_RS06670	COG0667	Aldo Keto reductase
AAJCM20276_RS06730	COG0552	protein localization to endoplasmic reticulum
AAJCM20276_RS06735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AAJCM20276_RS06740	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AAJCM20276_RS06755	COG0431	NADPH-dependent FMN reductase
AAJCM20276_RS06760	COG5001	Diguanylate cyclase
AAJCM20276_RS06770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AAJCM20276_RS06795	COG0481	GTPase activity
AAJCM20276_RS06800	COG2244	polysaccharide biosynthetic process
AAJCM20276_RS06805	COG0778	Nitroreductase
AAJCM20276_RS06810	COG0277	FAD linked oxidase domain protein
AAJCM20276_RS06815	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AAJCM20276_RS06825	COG0025	NhaP-type Na H and K H
AAJCM20276_RS06835	COG0484	heat shock protein binding
AAJCM20276_RS06845	COG0772	Belongs to the SEDS family
AAJCM20276_RS06850	COG0768	penicillin binding
AAJCM20276_RS06880	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AAJCM20276_RS06885	COG0193	aminoacyl-tRNA hydrolase activity
AAJCM20276_RS06890	COG0012	GTP binding
AAJCM20276_RS06895	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AAJCM20276_RS06900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AAJCM20276_RS06905	COG0799	negative regulation of ribosome biogenesis
AAJCM20276_RS06915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AAJCM20276_RS06920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AAJCM20276_RS06925	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AAJCM20276_RS06935	COG0505	Belongs to the CarA family
AAJCM20276_RS06945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAJCM20276_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_RS06975	COG0010	Belongs to the arginase family
AAJCM20276_RS06985	COG1610	YqeY-like protein
AAJCM20276_RS06990	COG0358	DNA primase activity
AAJCM20276_RS06995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AAJCM20276_RS07005	COG0360	Binds together with S18 to 16S ribosomal RNA
AAJCM20276_RS07010	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AAJCM20276_RS07015	COG0359	binds to the 23S rRNA
AAJCM20276_RS07020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AAJCM20276_RS07025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAJCM20276_RS07030	COG0527	aspartate kinase activity
AAJCM20276_RS07035	COG2070	2-Nitropropane dioxygenase
AAJCM20276_RS07045	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AAJCM20276_RS07050	COG0124	histidyl-tRNA synthetase
AAJCM20276_RS07055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AAJCM20276_RS07060	COG3706	GGDEF domain
AAJCM20276_RS07100	COG1530	ribonuclease E activity
AAJCM20276_RS07105	COG0556	nucleotide-excision repair
AAJCM20276_RS07120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AAJCM20276_RS07125	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AAJCM20276_RS07130	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AAJCM20276_RS07150	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_RS07165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAJCM20276_RS07175	COG2353	YceI-like domain
AAJCM20276_RS07185	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS07205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAJCM20276_RS07210	COG2814	Major facilitator Superfamily
AAJCM20276_RS07220	COG0259	pyridoxamine-phosphate oxidase activity
AAJCM20276_RS07225	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AAJCM20276_RS07230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AAJCM20276_RS07235	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AAJCM20276_RS07240	COG0604	alcohol dehydrogenase
AAJCM20276_RS07255	COG1902	pentaerythritol trinitrate reductase activity
AAJCM20276_RS07270	COG4974	Belongs to the 'phage' integrase family
AAJCM20276_RS07280	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_RS07305	COG0411	ABC transporter
AAJCM20276_RS07325	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS07340	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AAJCM20276_RS07345	COG0830	nickel cation binding
AAJCM20276_RS07355	COG0804	urea catabolic process
AAJCM20276_RS07360	COG0832	Belongs to the urease beta subunit family
AAJCM20276_RS07365	COG0831	urea catabolic process
AAJCM20276_RS07370	COG0829	nickel cation binding
AAJCM20276_RS07380	COG0248	Ppx GppA phosphatase
AAJCM20276_RS07415	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AAJCM20276_RS07420	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AAJCM20276_RS07425	COG0668	transmembrane transport
AAJCM20276_RS07435	COG0180	Tryptophanyl-tRNA synthetase
AAJCM20276_RS07450	COG0545	Peptidyl-prolyl cis-trans isomerase
AAJCM20276_RS07455	COG0137	argininosuccinate synthase activity
AAJCM20276_RS07465	COG0024	Methionine aminopeptidase
AAJCM20276_RS07480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AAJCM20276_RS07485	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AAJCM20276_RS07490	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AAJCM20276_RS07510	COG0513	Belongs to the DEAD box helicase family
AAJCM20276_RS07535	COG0564	pseudouridine synthase activity
AAJCM20276_RS07540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AAJCM20276_RS07550	COG2814	Major facilitator Superfamily
AAJCM20276_RS07565	COG4993	Dehydrogenase
AAJCM20276_RS07580	COG0114	fumarate hydratase activity
AAJCM20276_RS07585	COG0840	transmembrane signaling receptor activity
AAJCM20276_RS07590	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AAJCM20276_RS07600	COG4774	siderophore transport
AAJCM20276_RS07615	COG1663	tetraacyldisaccharide 4'-kinase activity
AAJCM20276_RS07620	COG1519	Transferase
AAJCM20276_RS07640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AAJCM20276_RS07645	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AAJCM20276_RS07650	COG0372	Belongs to the citrate synthase family
AAJCM20276_RS07655	COG2079	MmgE PrpD family protein
AAJCM20276_RS07660	COG1396	sequence-specific DNA binding
AAJCM20276_RS07660	COG3800	Transcriptional regulator
AAJCM20276_RS07705	COG2022	thiamine diphosphate biosynthetic process
AAJCM20276_RS07730	COG0564	pseudouridine synthase activity
AAJCM20276_RS07735	COG1674	ftsk spoiiie
AAJCM20276_RS07740	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AAJCM20276_RS07765	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS07770	COG1289	transmembrane transporter activity
AAJCM20276_RS07775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAJCM20276_RS07780	COG0540	Belongs to the ATCase OTCase family
AAJCM20276_RS07785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AAJCM20276_RS07790	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AAJCM20276_RS07795	COG0758	DNA mediated transformation
AAJCM20276_RS07800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AAJCM20276_RS07805	COG0557	exoribonuclease II activity
AAJCM20276_RS07810	COG0793	Belongs to the peptidase S41A family
AAJCM20276_RS07820	COG2885	chlorophyll binding
AAJCM20276_RS07820	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AAJCM20276_RS07825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AAJCM20276_RS07830	COG1959	2 iron, 2 sulfur cluster binding
AAJCM20276_RS07845	COG0187	DNA topoisomerase II activity
AAJCM20276_RS07855	COG0302	gtp cyclohydrolase
AAJCM20276_RS07860	COG2967	ApaG domain
AAJCM20276_RS07875	COG1215	transferase activity, transferring glycosyl groups
AAJCM20276_RS07890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAJCM20276_RS07930	COG0657	acetylesterase activity
AAJCM20276_RS07935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAJCM20276_RS07940	COG0717	Belongs to the dCTP deaminase family
AAJCM20276_RS07985	COG2204	response regulator
AAJCM20276_RS07990	COG1923	regulation of RNA biosynthetic process
AAJCM20276_RS07995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AAJCM20276_RS08010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AAJCM20276_RS08015	COG0450	alkyl hydroperoxide reductase
AAJCM20276_RS08020	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS08030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AAJCM20276_RS08040	COG0783	Belongs to the Dps family
AAJCM20276_RS08050	COG0142	geranyltranstransferase activity
AAJCM20276_RS08060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AAJCM20276_RS08070	COG1450	Type ii and iii secretion system protein
AAJCM20276_RS08105	COG2062	phosphohistidine phosphatase, SixA
AAJCM20276_RS08110	COG1605	Chorismate mutase
AAJCM20276_RS08110	COG0287	Prephenate dehydrogenase
AAJCM20276_RS08115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AAJCM20276_RS08125	COG1929	Belongs to the glycerate kinase type-1 family
AAJCM20276_RS08130	COG1607	acyl-coa hydrolase
AAJCM20276_RS08145	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AAJCM20276_RS08150	COG0632	four-way junction helicase activity
AAJCM20276_RS08155	COG2255	four-way junction helicase activity
AAJCM20276_RS08160	COG0824	Thioesterase
AAJCM20276_RS08170	COG0848	biopolymer transport protein
AAJCM20276_RS08180	COG0823	Involved in the tonB-independent uptake of proteins
AAJCM20276_RS08185	COG2885	chlorophyll binding
AAJCM20276_RS08195	COG0037	tRNA processing
AAJCM20276_RS08210	COG1045	serine acetyltransferase
AAJCM20276_RS08215	COG2814	Major facilitator Superfamily
AAJCM20276_RS08235	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS08240	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AAJCM20276_RS08245	COG0459	protein refolding
AAJCM20276_RS08255	COG1196	nuclear chromosome segregation
AAJCM20276_RS08260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AAJCM20276_RS08290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AAJCM20276_RS08300	COG2885	chlorophyll binding
AAJCM20276_RS08300	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AAJCM20276_RS08305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AAJCM20276_RS08320	COG0825	malonyl-CoA metabolic process
AAJCM20276_RS08325	COG1058	Belongs to the CinA family
AAJCM20276_RS08325	COG1546	Belongs to the CinA family
AAJCM20276_RS08330	COG0494	nUDIX hydrolase
AAJCM20276_RS08345	COG1862	Preprotein translocase
AAJCM20276_RS08370	COG0728	peptidoglycan biosynthetic process
AAJCM20276_RS08385	COG4993	Dehydrogenase
AAJCM20276_RS08390	COG4993	Dehydrogenase
AAJCM20276_RS08440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AAJCM20276_RS08445	COG0352	thiamine-phosphate diphosphorylase activity
AAJCM20276_RS08470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AAJCM20276_RS08475	COG1692	metallophosphoesterase
AAJCM20276_RS08490	COG2814	Major facilitator Superfamily
AAJCM20276_RS08495	COG0546	phosphoglycolate phosphatase activity
AAJCM20276_RS08500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AAJCM20276_RS08505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AAJCM20276_RS08510	COG0697	spore germination
AAJCM20276_RS08540	COG0546	phosphoglycolate phosphatase activity
AAJCM20276_RS08550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAJCM20276_RS08555	COG2003	Belongs to the UPF0758 family
AAJCM20276_RS08565	COG2308	Evidence 4 Homologs of previously reported genes of
AAJCM20276_RS08575	COG0596	Alpha beta hydrolase
AAJCM20276_RS08580	COG0076	glutamate decarboxylase activity
AAJCM20276_RS08595	COG0484	heat shock protein binding
AAJCM20276_RS08600	COG0271	Belongs to the BolA IbaG family
AAJCM20276_RS08635	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AAJCM20276_RS08640	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AAJCM20276_RS08645	COG2814	Major facilitator Superfamily
AAJCM20276_RS08650	COG0494	nUDIX hydrolase
AAJCM20276_RS08665	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AAJCM20276_RS08690	COG0254	rRNA binding
AAJCM20276_RS08695	COG1970	mechanosensitive ion channel activity
AAJCM20276_RS08710	COG1346	cytolysis
AAJCM20276_RS08720	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AAJCM20276_RS08725	COG2224	Isocitrate lyase
AAJCM20276_RS08730	COG1396	sequence-specific DNA binding
AAJCM20276_RS08730	COG3800	Transcriptional regulator
AAJCM20276_RS08735	COG1113	amino acid transport
AAJCM20276_RS08750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AAJCM20276_RS08755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AAJCM20276_RS08760	COG3585	molybdate ion transport
AAJCM20276_RS08765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAJCM20276_RS08770	COG0165	Argininosuccinate lyase
AAJCM20276_RS08785	COG3293	Transposase
AAJCM20276_RS08805	COG0531	amino acid
AAJCM20276_RS08810	COG1968	undecaprenyl-diphosphatase activity
AAJCM20276_RS08835	COG2951	lytic endotransglycosylase activity
AAJCM20276_RS08840	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AAJCM20276_RS08845	COG1686	Belongs to the peptidase S11 family
AAJCM20276_RS08850	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AAJCM20276_RS08860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAJCM20276_RS08865	COG0084	hydrolase, TatD family'
AAJCM20276_RS08875	COG2766	serine protein kinase
AAJCM20276_RS08880	COG2718	Belongs to the UPF0229 family
AAJCM20276_RS08885	COG2719	SpoVR family
AAJCM20276_RS08895	COG0596	Alpha beta hydrolase
AAJCM20276_RS08900	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_RS08900	COG0604	alcohol dehydrogenase
AAJCM20276_RS08900	COG3321	synthase
AAJCM20276_RS08905	COG0045	succinate-CoA ligase (ADP-forming) activity
AAJCM20276_RS08930	COG3206	protein involved in exopolysaccharide biosynthesis
AAJCM20276_RS08930	COG0489	protein tyrosine kinase activity
AAJCM20276_RS08965	COG1051	belongs to the nudix hydrolase family
AAJCM20276_RS08975	COG0793	Belongs to the peptidase S41A family
AAJCM20276_RS08985	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AAJCM20276_RS08995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAJCM20276_RS09000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AAJCM20276_RS09005	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AAJCM20276_RS09015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAJCM20276_RS09030	COG3008	intermembrane lipid transfer
AAJCM20276_RS09030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AAJCM20276_RS09035	COG1127	ABC transporter
AAJCM20276_RS09040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AAJCM20276_RS09045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AAJCM20276_RS09050	COG2999	glutathione oxidoreductase activity
AAJCM20276_RS09090	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AAJCM20276_RS09110	COG1706	bacterial-type flagellum-dependent cell motility
AAJCM20276_RS09130	COG0534	Mate efflux family protein
AAJCM20276_RS09145	COG1121	(ABC) transporter
AAJCM20276_RS09165	COG0659	secondary active sulfate transmembrane transporter activity
AAJCM20276_RS09170	COG0457	Tetratricopeptide repeat
AAJCM20276_RS09170	COG0859	PFAM glycosyl transferase family 9
AAJCM20276_RS09195	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_RS09230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AAJCM20276_RS09240	COG2226	methyltransferase
AAJCM20276_RS09250	COG0175	sulfate reduction
AAJCM20276_RS09255	COG0175	sulfate reduction
AAJCM20276_RS09275	COG1573	uracil-dna glycosylase
AAJCM20276_RS09305	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AAJCM20276_RS09330	COG0321	lipoyl(octanoyl) transferase activity
AAJCM20276_RS09360	COG0237	dephospho-CoA kinase activity
AAJCM20276_RS09365	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAJCM20276_RS09385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AAJCM20276_RS09390	COG0390	transport system, permease component
AAJCM20276_RS09415	COG2271	Major facilitator Superfamily
AAJCM20276_RS09425	COG0436	Aminotransferase
AAJCM20276_RS09435	COG1494	fructose-1,6-bisphosphatase
AAJCM20276_RS09440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AAJCM20276_RS09440	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AAJCM20276_RS09460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AAJCM20276_RS09465	COG0463	Glycosyl transferase, family 2
AAJCM20276_RS09470	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AAJCM20276_RS09475	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AAJCM20276_RS09480	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAJCM20276_RS09485	COG0356	it plays a direct role in the translocation of protons across the membrane
AAJCM20276_RS09505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AAJCM20276_RS09525	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AAJCM20276_RS09570	COG0432	Pfam Uncharacterised protein family UPF0047
AAJCM20276_RS09585	COG1132	(ABC) transporter
AAJCM20276_RS09595	COG1584	GPR1 FUN34 yaaH family protein
AAJCM20276_RS09610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AAJCM20276_RS09630	COG0019	diaminopimelate decarboxylase activity
AAJCM20276_RS09640	COG0463	Glycosyl transferase, family 2
AAJCM20276_RS09650	COG0539	negative regulation of cytoplasmic translation
AAJCM20276_RS09665	COG1289	transmembrane transporter activity
AAJCM20276_RS09690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAJCM20276_RS09700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAJCM20276_RS09710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AAJCM20276_RS09745	COG2165	general secretion pathway protein
AAJCM20276_RS09755	COG1459	type II secretion system
AAJCM20276_RS09760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AAJCM20276_RS09820	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AAJCM20276_RS09830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AAJCM20276_RS09840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AAJCM20276_RS09845	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AAJCM20276_RS09850	COG3800	Transcriptional regulator
AAJCM20276_RS09850	COG1396	sequence-specific DNA binding
AAJCM20276_RS09855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AAJCM20276_RS09860	COG0022	dehydrogenase e1 component
AAJCM20276_RS09860	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAJCM20276_RS09865	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAJCM20276_RS09870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAJCM20276_RS09880	COG0134	indole-3-glycerol-phosphate synthase activity
AAJCM20276_RS09885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AAJCM20276_RS09910	COG5328	Belongs to the UPF0262 family
AAJCM20276_RS09915	COG1648	precorrin-2 dehydrogenase activity
AAJCM20276_RS09915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AAJCM20276_RS09935	COG0861	Integral membrane protein TerC family
AAJCM20276_RS09940	COG0739	heme binding
AAJCM20276_RS09940	COG0741	lytic transglycosylase activity
AAJCM20276_RS09940	COG1196	nuclear chromosome segregation
AAJCM20276_RS09950	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AAJCM20276_RS09985	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AAJCM20276_RS10010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AAJCM20276_RS10015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AAJCM20276_RS10020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AAJCM20276_RS10025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AAJCM20276_RS10070	COG2249	NAD(P)H dehydrogenase (quinone) activity
AAJCM20276_RS10075	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS10090	COG2072	flavoprotein involved in K transport
AAJCM20276_RS10105	COG2144	transferase activity, transferring acyl groups
AAJCM20276_RS10130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AAJCM20276_RS10165	COG1278	Cold shock
AAJCM20276_RS10170	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AAJCM20276_RS10175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAJCM20276_RS10180	COG0077	Prephenate dehydratase
AAJCM20276_RS10180	COG1605	Chorismate mutase
AAJCM20276_RS10185	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AAJCM20276_RS10195	COG0483	inositol monophosphate 1-phosphatase activity
AAJCM20276_RS10200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAJCM20276_RS10205	COG0606	chelatase, subunit chli
AAJCM20276_RS10220	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AAJCM20276_RS10240	COG1858	cytochrome C peroxidase
AAJCM20276_RS10305	COG4964	Belongs to the GSP D family
AAJCM20276_RS10310	COG3293	Transposase
AAJCM20276_RS10340	COG2132	Multicopper oxidase
AAJCM20276_RS10350	COG1566	PFAM secretion protein HlyD family protein
AAJCM20276_RS10375	COG0837	glucose binding
AAJCM20276_RS10385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AAJCM20276_RS10400	COG0525	valine-tRNA ligase activity
AAJCM20276_RS10405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAJCM20276_RS10415	COG3293	Transposase
AAJCM20276_RS10430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AAJCM20276_RS10440	COG0752	glycyl-tRNA synthetase alpha subunit
AAJCM20276_RS10495	COG0789	Transcriptional regulator
AAJCM20276_RS10510	COG0477	Major facilitator Superfamily
AAJCM20276_RS10520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AAJCM20276_RS10525	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AAJCM20276_RS10535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAJCM20276_RS10540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AAJCM20276_RS10565	COG2995	paraquat-inducible protein a
AAJCM20276_RS10610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AAJCM20276_RS10615	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AAJCM20276_RS10625	COG0535	radical SAM domain protein
AAJCM20276_RS10640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AAJCM20276_RS10645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAJCM20276_RS10655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AAJCM20276_RS10680	COG3590	peptidase
AAJCM20276_RS10695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AAJCM20276_RS10700	COG1764	response to oxidative stress
AAJCM20276_RS10710	COG3511	phospholipase C
AAJCM20276_RS10715	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AAJCM20276_RS10720	COG2894	cell division
AAJCM20276_RS10725	COG0850	regulation of cytokinetic process
AAJCM20276_RS10735	COG0402	S-adenosylhomocysteine deaminase activity
AAJCM20276_RS10740	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAJCM20276_RS10755	COG3608	succinylglutamate desuccinylase aspartoacylase
AAJCM20276_RS10755	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AAJCM20276_RS10765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAJCM20276_RS10805	COG1278	Cold shock
AAJCM20276_RS10810	COG1393	Belongs to the ArsC family
AAJCM20276_RS10815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AAJCM20276_RS10840	COG1160	GTP binding
AAJCM20276_RS10845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AAJCM20276_RS10875	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_RS10905	COG3306	glycosyltransferase involved in LPS biosynthesis
AAJCM20276_RS10925	COG2267	carboxylic ester hydrolase activity
AAJCM20276_RS10935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAJCM20276_RS10935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAJCM20276_RS10945	COG0747	negative chemotaxis
AAJCM20276_RS10950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAJCM20276_RS10965	COG4608	Belongs to the ABC transporter superfamily
AAJCM20276_RS10975	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AAJCM20276_RS10995	COG1045	serine acetyltransferase
AAJCM20276_RS11025	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AAJCM20276_RS11030	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AAJCM20276_RS11035	COG4208	sulfate ABC transporter
AAJCM20276_RS11040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AAJCM20276_RS11050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AAJCM20276_RS11060	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_RS11090	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_RS11095	COG1120	ATPase activity
AAJCM20276_RS11120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAJCM20276_RS11120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AAJCM20276_RS11130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AAJCM20276_RS11140	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_RS11150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AAJCM20276_RS11155	COG2171	N-acyltransferase activity
AAJCM20276_RS11160	COG2199	diguanylate cyclase activity
AAJCM20276_RS11170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AAJCM20276_RS11175	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAJCM20276_RS11180	COG0154	amidase activity
AAJCM20276_RS11185	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAJCM20276_RS11190	COG2264	protein methyltransferase activity
AAJCM20276_RS11195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AAJCM20276_RS11200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAJCM20276_RS11205	COG1518	maintenance of DNA repeat elements
AAJCM20276_RS11220	COG1857	crispr-associated protein
AAJCM20276_RS11235	COG1203	CRISPR-associated helicase, Cas3
AAJCM20276_RS11240	COG1132	(ABC) transporter
AAJCM20276_RS11245	COG0617	tRNA 3'-terminal CCA addition
AAJCM20276_RS11255	COG0714	Associated with various cellular activities
AAJCM20276_RS11275	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AAJCM20276_RS11285	COG1185	polyribonucleotide nucleotidyltransferase activity
AAJCM20276_RS11295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AAJCM20276_RS11300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AAJCM20276_RS11305	COG0739	heme binding
AAJCM20276_RS11305	COG0741	lytic transglycosylase activity
AAJCM20276_RS11305	COG1196	nuclear chromosome segregation
AAJCM20276_RS11315	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AAJCM20276_RS11320	COG1686	Belongs to the peptidase S11 family
AAJCM20276_RS11325	COG2890	protein-(glutamine-N5) methyltransferase activity
AAJCM20276_RS11335	COG0277	FAD linked oxidase domain protein
AAJCM20276_RS11365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AAJCM20276_RS11370	COG1702	phosphate starvation-inducible protein PhoH
AAJCM20276_RS11375	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AAJCM20276_RS11400	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AAJCM20276_RS11410	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AAJCM20276_RS11415	COG0268	Binds directly to 16S ribosomal RNA
AAJCM20276_RS11420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AAJCM20276_RS11425	COG2226	methyltransferase
AAJCM20276_RS11435	COG0756	dUTP diphosphatase activity
AAJCM20276_RS11445	COG1116	anion transmembrane transporter activity
AAJCM20276_RS11455	COG0612	Peptidase, M16
AAJCM20276_RS11460	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_RS11465	COG1511	domain protein
AAJCM20276_RS11465	COG3264	Mechanosensitive ion channel
AAJCM20276_RS11470	COG1297	OPT oligopeptide transporter protein
AAJCM20276_RS11485	COG2217	Heavy metal translocating P-type atpase
AAJCM20276_RS11505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAJCM20276_RS11510	COG1621	beta-fructofuranosidase activity
AAJCM20276_RS11525	COG1032	radical SAM domain protein
AAJCM20276_RS11545	COG1414	Transcriptional regulator
AAJCM20276_RS11555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AAJCM20276_RS11570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AAJCM20276_RS11590	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AAJCM20276_RS11595	COG5373	membrane
AAJCM20276_RS11595	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AAJCM20276_RS11610	COG0779	Required for maturation of 30S ribosomal subunits
AAJCM20276_RS11620	COG0542	response to heat
AAJCM20276_RS11630	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS11635	COG0765	amino acid transport
AAJCM20276_RS11640	COG1126	abc transporter atp-binding protein
AAJCM20276_RS11645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AAJCM20276_RS11650	COG4133	protoheme IX ABC transporter activity
AAJCM20276_RS11655	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAJCM20276_RS11660	COG1253	flavin adenine dinucleotide binding
AAJCM20276_RS11665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AAJCM20276_RS11685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AAJCM20276_RS11690	COG3394	polysaccharide catabolic process
AAJCM20276_RS11700	COG2945	thiolester hydrolase activity
AAJCM20276_RS11705	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AAJCM20276_RS11715	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AAJCM20276_RS11715	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AAJCM20276_RS11730	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AAJCM20276_RS11745	COG0523	cobalamin synthesis protein
AAJCM20276_RS11760	COG0590	tRNA wobble adenosine to inosine editing
AAJCM20276_RS11770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AAJCM20276_RS11775	COG1187	pseudouridine synthase activity
AAJCM20276_RS11780	COG0742	ribosomal rna small subunit methyltransferase
AAJCM20276_RS11795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AAJCM20276_RS11800	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AAJCM20276_RS11810	COG4206	TonB-dependent receptor
AAJCM20276_RS11815	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AAJCM20276_RS11820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AAJCM20276_RS11860	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AAJCM20276_RS11865	COG0386	Belongs to the glutathione peroxidase family
AAJCM20276_RS11875	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAJCM20276_RS11890	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AAJCM20276_RS11895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAJCM20276_RS11900	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AAJCM20276_RS11965	COG0306	phosphate transporter
AAJCM20276_RS11970	COG0633	Ferredoxin
AAJCM20276_RS11970	COG3217	Mosc domain protein beta barrel domain protein
AAJCM20276_RS11975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AAJCM20276_RS11985	COG0149	triose-phosphate isomerase activity
AAJCM20276_RS12000	COG0504	CTP synthase activity
AAJCM20276_RS12005	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AAJCM20276_RS12015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AAJCM20276_RS12025	COG0217	transcriptional regulatory protein
AAJCM20276_RS12030	COG0653	protein targeting
AAJCM20276_RS12035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAJCM20276_RS12040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AAJCM20276_RS12045	COG1714	RDD family
AAJCM20276_RS12050	COG0668	transmembrane transport
AAJCM20276_RS12065	COG4771	TonB-dependent receptor
AAJCM20276_RS12070	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS12075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAJCM20276_RS12105	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AAJCM20276_RS12115	COG1127	ABC transporter
AAJCM20276_RS12120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AAJCM20276_RS12145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AAJCM20276_RS12150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AAJCM20276_RS12160	COG3293	Transposase
AAJCM20276_RS12165	COG2003	Belongs to the UPF0758 family
AAJCM20276_RS12170	COG2814	Major facilitator Superfamily
AAJCM20276_RS12175	COG1566	PFAM secretion protein HlyD family protein
AAJCM20276_RS12205	COG1987	bacterial-type flagellum assembly
AAJCM20276_RS12210	COG1677	Flagellar hook-basal body complex protein FliE
AAJCM20276_RS12215	COG1558	bacterial-type flagellum-dependent cell motility
AAJCM20276_RS12220	COG1815	bacterial-type flagellum-dependent cell motility
AAJCM20276_RS12230	COG1338	Plays a role in the flagellum-specific transport system
AAJCM20276_RS12235	COG1136	(ABC) transporter
AAJCM20276_RS12245	COG0442	prolyl-tRNA aminoacylation
AAJCM20276_RS12260	COG0493	'glutamate synthase
AAJCM20276_RS12280	COG1953	Uracil, thiamine, allantoin
AAJCM20276_RS12295	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AAJCM20276_RS12305	COG1007	ATP synthesis coupled electron transport
AAJCM20276_RS12325	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_RS12330	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AAJCM20276_RS12335	COG1034	ATP synthesis coupled electron transport
AAJCM20276_RS12345	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AAJCM20276_RS12350	COG0649	NAD binding
AAJCM20276_RS12355	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_RS12360	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_RS12365	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_RS12375	COG0776	regulation of translation
AAJCM20276_RS12385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AAJCM20276_RS12390	COG0740	serine-type endopeptidase activity
AAJCM20276_RS12395	COG0544	peptidyl-prolyl cis-trans isomerase activity
AAJCM20276_RS12405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AAJCM20276_RS12405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AAJCM20276_RS12415	COG0513	Belongs to the DEAD box helicase family
AAJCM20276_RS12450	COG2814	Major facilitator Superfamily
AAJCM20276_RS12475	COG3300	MHYT domain
AAJCM20276_RS12475	COG5001	Diguanylate cyclase
AAJCM20276_RS12480	COG3300	MHYT domain
AAJCM20276_RS12480	COG5001	Diguanylate cyclase
AAJCM20276_RS12485	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AAJCM20276_RS12495	COG3265	gluconokinase activity
AAJCM20276_RS12500	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AAJCM20276_RS12505	COG0363	glucosamine-6-phosphate deaminase activity
AAJCM20276_RS12510	COG0561	phosphatase activity
AAJCM20276_RS12515	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AAJCM20276_RS12520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AAJCM20276_RS12535	COG1570	exodeoxyribonuclease VII activity
AAJCM20276_RS12545	COG0179	Fumarylacetoacetate (FAA) hydrolase
AAJCM20276_RS12550	COG1216	Glycosyl transferase, family 2
AAJCM20276_RS12550	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_RS12560	COG1657	PFAM Prenyltransferase squalene oxidase
AAJCM20276_RS12565	COG1233	COG1233 Phytoene dehydrogenase and related
AAJCM20276_RS12570	COG1562	ergosterol biosynthetic process
AAJCM20276_RS12575	COG1562	ergosterol biosynthetic process
AAJCM20276_RS12580	COG2816	NAD+ diphosphatase activity
AAJCM20276_RS12590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AAJCM20276_RS12600	COG0287	Prephenate dehydrogenase
AAJCM20276_RS12620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAJCM20276_RS12630	COG0109	protoheme IX farnesyltransferase activity
AAJCM20276_RS12640	COG2226	methyltransferase
AAJCM20276_RS12650	COG0189	ligase activity
AAJCM20276_RS12660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AAJCM20276_RS12665	COG1360	Flagellar Motor Protein
AAJCM20276_RS12680	COG1522	sequence-specific DNA binding
AAJCM20276_RS12685	COG0492	ferredoxin-NADP+ reductase activity
AAJCM20276_RS12690	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS12695	COG1321	iron dependent repressor
AAJCM20276_RS12730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AAJCM20276_RS12745	COG0616	signal peptide processing
AAJCM20276_RS12750	COG0776	regulation of translation
AAJCM20276_RS12760	COG0662	Cupin 2, conserved barrel domain protein
AAJCM20276_RS12760	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AAJCM20276_RS12780	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AAJCM20276_RS12785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AAJCM20276_RS12795	COG1607	acyl-coa hydrolase
AAJCM20276_RS12800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AAJCM20276_RS12805	COG0354	folic acid binding
AAJCM20276_RS12810	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AAJCM20276_RS12815	COG0242	peptide deformylase activity
AAJCM20276_RS12825	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AAJCM20276_RS12840	COG1722	exodeoxyribonuclease VII activity
AAJCM20276_RS12865	COG1940	carbohydrate kinase activity
AAJCM20276_RS12870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AAJCM20276_RS12875	COG0316	Belongs to the HesB IscA family
AAJCM20276_RS12880	COG2151	metal-sulfur cluster biosynthetic enzyme
AAJCM20276_RS12890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AAJCM20276_RS12895	COG0719	Fe-S assembly protein
AAJCM20276_RS12900	COG0396	ATPase activity
AAJCM20276_RS12905	COG0719	Fe-S assembly protein
AAJCM20276_RS12910	COG1959	2 iron, 2 sulfur cluster binding
AAJCM20276_RS12920	COG2733	membrane
AAJCM20276_RS12940	COG0156	8-amino-7-oxononanoate synthase activity
AAJCM20276_RS12960	COG0126	phosphoglycerate kinase activity
AAJCM20276_RS13155	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AAJCM20276_RS13260	COG5484	DNA packaging
AAJCM20276_RS13260	COG3728	DNA packaging
AAJCM20276_RS13295	COG1061	Type III restriction enzyme res subunit
AAJCM20276_RS13445	COG2205	protein histidine kinase activity
AAJCM20276_RS13475	COG2223	nitrite transmembrane transporter activity
AAJCM20276_RS13485	COG2146	nitrite reductase [NAD(P)H] activity
AAJCM20276_RS13485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AAJCM20276_RS13490	COG0243	molybdopterin cofactor binding
AAJCM20276_RS13500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AAJCM20276_RS13500	COG1116	anion transmembrane transporter activity
AAJCM20276_RS13515	COG0803	Belongs to the bacterial solute-binding protein 9 family
AAJCM20276_RS13530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AAJCM20276_RS13535	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AAJCM20276_RS13545	COG5265	(ABC) transporter
AAJCM20276_RS13565	COG2226	methyltransferase
AAJCM20276_RS13565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAJCM20276_RS13565	COG0596	Alpha beta hydrolase
AAJCM20276_RS13595	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AAJCM20276_RS13595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AAJCM20276_RS13600	COG0737	Belongs to the 5'-nucleotidase family
AAJCM20276_RS13605	COG3572	ergothioneine biosynthetic process
AAJCM20276_RS13615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AAJCM20276_RS13625	COG0513	Belongs to the DEAD box helicase family
AAJCM20276_RS13630	COG4106	trans-aconitate 2-methyltransferase activity
AAJCM20276_RS13630	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AAJCM20276_RS13640	COG0156	8-amino-7-oxononanoate synthase activity
AAJCM20276_RS13650	COG0314	molybdopterin synthase activity
AAJCM20276_RS13655	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AAJCM20276_RS13665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AAJCM20276_RS13670	COG0322	excinuclease ABC activity
AAJCM20276_RS13685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAJCM20276_RS13705	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_RS13730	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AAJCM20276_RS13745	COG1216	Glycosyl transferase, family 2
AAJCM20276_RS13745	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_RS13760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAJCM20276_RS13775	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AAJCM20276_RS13780	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AAJCM20276_RS13785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AAJCM20276_RS13790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AAJCM20276_RS13795	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AAJCM20276_RS13800	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AAJCM20276_RS13805	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAJCM20276_RS13825	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AAJCM20276_RS13840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AAJCM20276_RS13850	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AAJCM20276_RS13855	COG1053	succinate dehydrogenase
AAJCM20276_RS13860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AAJCM20276_RS13875	COG2824	Alkylphosphonate utilization operon protein PhnA
AAJCM20276_RS13885	COG3920	Histidine kinase
AAJCM20276_RS13885	COG2202	Pas domain
AAJCM20276_RS13895	COG0488	(ABC) transporter
AAJCM20276_RS13905	COG0628	permease
AAJCM20276_RS13945	COG0006	proline dipeptidase activity
AAJCM20276_RS13950	COG0473	3-isopropylmalate dehydrogenase activity
AAJCM20276_RS14000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AAJCM20276_RS14005	COG0072	phenylalanine-tRNA ligase activity
AAJCM20276_RS14005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAJCM20276_RS14010	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AAJCM20276_RS14015	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AAJCM20276_RS14040	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AAJCM20276_RS14045	COG2203	Gaf domain
AAJCM20276_RS14045	COG3706	GGDEF domain
AAJCM20276_RS14045	COG5001	Diguanylate cyclase
AAJCM20276_RS14045	COG4251	negative regulation of phosphorylation
AAJCM20276_RS14065	COG0612	Peptidase, M16
AAJCM20276_RS14070	COG0312	modulator of DNA gyrase
AAJCM20276_RS14080	COG2755	lipolytic protein G-D-S-L family
AAJCM20276_RS14080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AAJCM20276_RS14090	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AAJCM20276_RS14095	COG1454	alcohol dehydrogenase
AAJCM20276_RS14100	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AAJCM20276_RS14100	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AAJCM20276_RS14105	COG0194	GDP metabolic process
AAJCM20276_RS14110	COG0300	oxidoreductase activity
AAJCM20276_RS14115	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAJCM20276_RS14175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AAJCM20276_RS14220	COG0415	Belongs to the DNA photolyase family
AAJCM20276_RS14255	COG1566	PFAM secretion protein HlyD family protein
AAJCM20276_RS14315	COG0586	Pfam SNARE associated Golgi protein
AAJCM20276_RS14320	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_RS14325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAJCM20276_RS14335	COG0140	phosphoribosyl-ATP diphosphatase activity
AAJCM20276_RS14340	COG0107	imidazoleglycerol-phosphate synthase activity
AAJCM20276_RS14345	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AAJCM20276_RS14350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AAJCM20276_RS14360	COG0131	Imidazoleglycerol-phosphate dehydratase
AAJCM20276_RS14365	COG3300	MHYT domain
AAJCM20276_RS14365	COG5001	Diguanylate cyclase
AAJCM20276_RS14390	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AAJCM20276_RS14415	COG1199	ATP-dependent helicase activity
AAJCM20276_RS14460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AAJCM20276_RS14505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AAJCM20276_RS14510	COG0531	amino acid
AAJCM20276_RS14515	COG1253	flavin adenine dinucleotide binding
AAJCM20276_RS14520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AAJCM20276_RS14525	COG1671	Belongs to the UPF0178 family
AAJCM20276_RS14540	COG1597	lipid kinase activity
AAJCM20276_RS14550	COG2326	polyphosphate kinase activity
AAJCM20276_RS14555	COG4221	oxidoreductase activity
AAJCM20276_RS14560	COG1678	Uncharacterized ACR, COG1678
AAJCM20276_RS14585	COG1217	gtp-binding protein TYPA
AAJCM20276_RS14615	COG2818	Glycosylase
AAJCM20276_RS14620	COG0473	3-isopropylmalate dehydrogenase activity
AAJCM20276_RS14630	COG1335	isochorismatase
AAJCM20276_RS14640	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS14645	COG1289	transmembrane transporter activity
AAJCM20276_RS14650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AAJCM20276_RS14660	COG2814	Major facilitator Superfamily
AAJCM20276_RS14675	COG1612	heme a metabolic process
AAJCM20276_RS14705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AAJCM20276_RS14730	COG0489	protein tyrosine kinase activity
AAJCM20276_RS14745	COG0741	lytic transglycosylase activity
AAJCM20276_RS14750	COG1573	uracil-dna glycosylase
AAJCM20276_RS14765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AAJCM20276_RS14770	COG0066	3-isopropylmalate dehydratase activity
AAJCM20276_RS14780	COG0778	Nitroreductase
AAJCM20276_RS14785	COG3042	response to heat
AAJCM20276_RS14795	COG0581	inorganic phosphate transmembrane transporter activity
AAJCM20276_RS14800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AAJCM20276_RS14810	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_RS14820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AAJCM20276_RS14830	COG0335	large ribosomal subunit rRNA binding
AAJCM20276_RS14835	COG0336	Belongs to the RNA methyltransferase TrmD family
AAJCM20276_RS14840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AAJCM20276_RS14845	COG0228	four-way junction DNA binding
AAJCM20276_RS14880	COG0347	Belongs to the P(II) protein family
AAJCM20276_RS14885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AAJCM20276_RS14895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAJCM20276_RS14910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AAJCM20276_RS14915	COG1942	4-Oxalocrotonate Tautomerase
AAJCM20276_RS14925	COG4303	Ethanolamine ammonia lyase large subunit
AAJCM20276_RS14930	COG4302	ethanolamine ammonia-lyase activity
AAJCM20276_RS14935	COG0531	amino acid
AAJCM20276_RS14945	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AAJCM20276_RS14955	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AAJCM20276_RS14965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AAJCM20276_RS14990	COG3660	Nucleoside-diphosphate-sugar epimerase
AAJCM20276_RS14995	COG0148	phosphopyruvate hydratase activity
AAJCM20276_RS15005	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AAJCM20276_RS15010	COG0303	'Molybdopterin
AAJCM20276_RS15025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AAJCM20276_RS15030	COG0285	dihydrofolate synthase activity
AAJCM20276_RS15045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AAJCM20276_RS15055	COG1177	transmembrane transport
AAJCM20276_RS15060	COG1176	ABC-type spermidine putrescine transport system, permease component I
AAJCM20276_RS15065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AAJCM20276_RS15070	COG3842	ATPase activity
AAJCM20276_RS15095	COG0848	biopolymer transport protein
AAJCM20276_RS15110	COG4774	siderophore transport
AAJCM20276_RS15115	COG3128	pkhd-type hydroxylase
AAJCM20276_RS15125	COG0167	dihydroorotate dehydrogenase activity
AAJCM20276_RS15130	COG5487	UPF0391 membrane protein
AAJCM20276_RS15140	COG1116	anion transmembrane transporter activity
AAJCM20276_RS15155	COG0203	ribosomal protein L17
AAJCM20276_RS15160	COG0202	RNA polymerase activity
AAJCM20276_RS15165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AAJCM20276_RS15170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AAJCM20276_RS15175	COG0563	adenylate kinase activity
AAJCM20276_RS15180	COG0201	protein transport
AAJCM20276_RS15185	COG0200	Binds to the 23S rRNA
AAJCM20276_RS15190	COG1841	ribosomal large subunit assembly
AAJCM20276_RS15195	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AAJCM20276_RS15200	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AAJCM20276_RS15205	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AAJCM20276_RS15210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AAJCM20276_RS15215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AAJCM20276_RS15220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AAJCM20276_RS15225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AAJCM20276_RS15230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AAJCM20276_RS15235	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AAJCM20276_RS15240	COG0255	Belongs to the universal ribosomal protein uL29 family
AAJCM20276_RS15245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AAJCM20276_RS15250	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AAJCM20276_RS15255	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AAJCM20276_RS15260	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AAJCM20276_RS15265	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AAJCM20276_RS15270	COG0089	rRNA binding
AAJCM20276_RS15275	COG0088	Forms part of the polypeptide exit tunnel
AAJCM20276_RS15280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AAJCM20276_RS15285	COG0051	transcription antitermination factor activity, RNA binding
AAJCM20276_RS15290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AAJCM20276_RS15295	COG0049	tRNA binding
AAJCM20276_RS15300	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AAJCM20276_RS15305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAJCM20276_RS15315	COG0085	RNA polymerase activity
AAJCM20276_RS15320	COG0222	ribosome binding
AAJCM20276_RS15325	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AAJCM20276_RS15330	COG0081	regulation of translation
AAJCM20276_RS15335	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AAJCM20276_RS15350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAJCM20276_RS15355	COG0235	Class ii aldolase
AAJCM20276_RS15360	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AAJCM20276_RS15365	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AAJCM20276_RS15370	COG0196	riboflavin kinase activity
AAJCM20276_RS15380	COG4716	Myosin-crossreactive antigen
AAJCM20276_RS15410	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_RS15415	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_RS15420	COG0649	NAD binding
AAJCM20276_RS15420	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_RS15440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AAJCM20276_RS15445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_RS15450	COG0839	Belongs to the complex I subunit 6 family
AAJCM20276_RS15455	COG0713	ATP synthesis coupled electron transport
AAJCM20276_RS15470	COG1007	ATP synthesis coupled electron transport
AAJCM20276_RS15475	COG0517	IMP dehydrogenase activity
AAJCM20276_RS15475	COG0516	GMP reductase activity
AAJCM20276_RS15495	COG4993	Dehydrogenase
AAJCM20276_RS15505	COG2010	Cytochrome c
AAJCM20276_RS15540	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AAJCM20276_RS15545	COG2943	transferase activity, transferring hexosyl groups
AAJCM20276_RS15560	COG0658	competence protein
AAJCM20276_RS15560	COG2333	competence protein COMEC
AAJCM20276_RS15580	COG0483	inositol monophosphate 1-phosphatase activity
AAJCM20276_RS15585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AAJCM20276_RS15600	COG0776	regulation of translation
AAJCM20276_RS15605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AAJCM20276_RS15610	COG0416	fatty acid biosynthetic process
AAJCM20276_RS15615	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AAJCM20276_RS15635	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_RS15650	COG0242	peptide deformylase activity
AAJCM20276_RS15655	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AAJCM20276_RS15705	COG0646	methionine synthase
AAJCM20276_RS15705	COG1410	methionine synthase
AAJCM20276_RS15710	COG3293	Transposase
AAJCM20276_RS15725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AAJCM20276_RS15730	COG0492	ferredoxin-NADP+ reductase activity
AAJCM20276_RS15735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_RS15740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AAJCM20276_RS15745	COG2814	Major facilitator Superfamily
AAJCM20276_RS15765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AAJCM20276_RS15775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AAJCM20276_RS15785	COG0598	Magnesium transport protein CorA
AAJCM20276_RS15800	COG1091	dTDP-4-dehydrorhamnose reductase activity
AAJCM20276_RS15810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AAJCM20276_RS15835	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS15840	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_RS15855	COG0523	cobalamin synthesis protein
AAJCM20276_RS15865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AAJCM20276_RS15870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAJCM20276_RS15880	COG2814	Major facilitator Superfamily
AAJCM20276_RS15895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AAJCM20276_RS15905	COG2897	thiosulfate sulfurtransferase activity
AAJCM20276_RS15915	COG0628	permease
AAJCM20276_RS15930	COG3047	cAMP biosynthetic process
AAJCM20276_RS15935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAJCM20276_RS15945	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AAJCM20276_RS15955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AAJCM20276_RS15980	COG2814	Major facilitator Superfamily
AAJCM20276_RS16015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AAJCM20276_RS16025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AAJCM20276_RS16035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AAJCM20276_RS16040	COG2113	Glycine betaine
AAJCM20276_RS16045	COG4175	Glycine betaine
AAJCM20276_RS16045	COG3448	diguanylate cyclase activity
AAJCM20276_RS16050	COG4176	ABC-type proline glycine betaine transport system permease component
AAJCM20276_RS16070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AAJCM20276_RS16085	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAJCM20276_RS16085	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AAJCM20276_RS16090	COG4311	Sarcosine oxidase, delta subunit
AAJCM20276_RS16095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_RS16110	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AAJCM20276_RS16115	COG2218	PFAM glutamate synthase alpha subunit domain protein
AAJCM20276_RS16120	COG0069	glutamate synthase activity
AAJCM20276_RS16130	COG0004	ammonium transporteR
AAJCM20276_RS16135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_RS16170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AAJCM20276_RS16285	COG0583	DNA-binding transcription factor activity
AAJCM20276_RS16355	COG0439	Biotin carboxylase
AAJCM20276_RS16365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AAJCM20276_RS16370	COG1984	allophanate hydrolase subunit 2
AAJCM20276_RS16380	COG2271	Major facilitator Superfamily
AAJCM20276_RS16390	COG2271	Major facilitator Superfamily
AAJCM20276_RS16405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAJCM20276_RS16450	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_RS16495	COG4735	regulation of single-species biofilm formation
AAJCM20276_RS16515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AAJCM20276_RS16605	COG3550	peptidyl-serine autophosphorylation
AAJCM20276_RS16655	COG2755	lipolytic protein G-D-S-L family
AAJCM20276_RS16655	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AAJCM20276_RS16670	COG0251	oxidation-reduction process
AAJCM20276_RS16675	COG0604	alcohol dehydrogenase
AAJCM20276_RS16700	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AAJCM20276_RS16745	COG0495	leucyl-tRNA aminoacylation
AAJCM20276_RS16760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AAJCM20276_RS16765	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AAJCM20276_RS16775	COG0018	arginyl-trna synthetase
AAJCM20276_RS16795	COG1368	sulfuric ester hydrolase activity
AAJCM20276_RS16800	COG2226	methyltransferase
AAJCM20276_RS16810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAJCM20276_RS16815	COG0318	PFAM AMP-dependent synthetase and ligase
AAJCM20276_RS16910	COG0656	L-ascorbic acid biosynthetic process
AAJCM20276_RS16920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AAJCM20276_RS16930	COG2814	Major facilitator Superfamily
AAJCM20276_RS16940	COG0009	L-threonylcarbamoyladenylate synthase
AAJCM20276_RS16960	COG0305	Participates in initiation and elongation during chromosome replication
AAJCM20276_RS16975	COG1289	transmembrane transporter activity
AAJCM20276_RS16990	COG1492	cobalamin metabolic process
AAJCM20276_RS17000	COG1797	cobyrinic acid a,c-diamide synthase activity
AAJCM20276_RS17030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AAJCM20276_RS17040	COG1194	a g-specific adenine glycosylase
AAJCM20276_RS17055	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_RS17060	COG0753	catalase activity
AAJCM20276_RS17080	COG1960	acyl-CoA dehydrogenase activity
AAJCM20276_RS17085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AAJCM20276_RS17090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAJCM20276_RS17095	COG1116	anion transmembrane transporter activity
AAJCM20276_RS17120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_RS17180	COG3547	Transposase (IS116 IS110 IS902 family)
AAJCM20276_RS17205	COG1216	Glycosyl transferase, family 2
AAJCM20276_RS17230	COG3436	PFAM IS66 Orf2 family protein
AAJCM20276_RS17295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AAJCM20276_RS17320	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AAJCM20276_RS17400	COG4372	Transposase
AAJCM20276_RS17405	COG3436	PFAM IS66 Orf2 family protein
AAJCM20276_RS17465	COG1476	TRANSCRIPTIONal
AAJCM20276_RS17545	COG1192	Involved in chromosome partitioning
AAJCM20276_RS17610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AAJCM20276_RS17730	COG3831	ATPase activity
AAJCM20276_RS17855	COG3344	reverse transcriptase
AAJCM20276_RS17900	COG2184	nucleotidyltransferase activity
AAJCM20276_RS17935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AAJCM20276_RS17945	COG3547	Transposase (IS116 IS110 IS902 family)
AAJCM20276_RS18005	COG2132	Multicopper oxidase
AAJCM20276_RS18015	COG1937	Protein conserved in bacteria
AAJCM20276_RS18040	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AAJCM20276_RS18130	COG0789	Transcriptional regulator
AAJCM20276_RS18175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AAJCM20276_RS18230	COG4644	lycopene metabolic process
AAJCM20276_RS18275	COG4115	mRNA cleavage
AAJCM20276_RS18280	COG2161	toxin-antitoxin pair type II binding