locus-tag	class	description
A0U92_RS00030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A0U92_RS00035	COG0805	protein transport
A0U92_RS00040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A0U92_RS00050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A0U92_RS00055	COG0022	dehydrogenase e1 component
A0U92_RS00065	COG1028	Short-chain dehydrogenase reductase Sdr
A0U92_RS00075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A0U92_RS00090	COG1393	Belongs to the ArsC family
A0U92_RS00110	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A0U92_RS00125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A0U92_RS00145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A0U92_RS00155	COG0488	(ABC) transporter
A0U92_RS00185	COG4993	Dehydrogenase
A0U92_RS00195	COG1957	nucleoside hydrolase
A0U92_RS00200	COG0251	oxidation-reduction process
A0U92_RS00205	COG0604	alcohol dehydrogenase
A0U92_RS00225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A0U92_RS00245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0U92_RS00270	COG0495	leucyl-tRNA aminoacylation
A0U92_RS00295	COG0018	arginyl-trna synthetase
A0U92_RS00305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A0U92_RS00310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A0U92_RS00330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A0U92_RS00335	COG2070	2-Nitropropane dioxygenase
A0U92_RS00345	COG0129	dihydroxy-acid dehydratase activity
A0U92_RS00355	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A0U92_RS00360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A0U92_RS00360	COG2857	Cytochrome c1
A0U92_RS00365	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A0U92_RS00375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A0U92_RS00385	COG3047	cAMP biosynthetic process
A0U92_RS00395	COG0628	permease
A0U92_RS00405	COG2897	thiosulfate sulfurtransferase activity
A0U92_RS00415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A0U92_RS00425	COG2814	Major facilitator Superfamily
A0U92_RS00455	COG2837	iron assimilation
A0U92_RS00470	COG2223	nitrite transmembrane transporter activity
A0U92_RS00480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0U92_RS00480	COG2146	nitrite reductase [NAD(P)H] activity
A0U92_RS00485	COG0243	molybdopterin cofactor binding
A0U92_RS00495	COG1116	anion transmembrane transporter activity
A0U92_RS00495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0U92_RS00565	COG0515	serine threonine protein kinase
A0U92_RS00610	COG1199	ATP-dependent helicase activity
A0U92_RS00630	COG0753	catalase activity
A0U92_RS00640	COG1012	belongs to the aldehyde dehydrogenase family
A0U92_RS00655	COG1194	a g-specific adenine glycosylase
A0U92_RS00665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A0U92_RS00710	COG1797	cobyrinic acid a,c-diamide synthase activity
A0U92_RS00720	COG1492	cobalamin metabolic process
A0U92_RS00740	COG1289	transmembrane transporter activity
A0U92_RS00755	COG0196	riboflavin kinase activity
A0U92_RS00760	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
A0U92_RS00765	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
A0U92_RS00770	COG0235	Class ii aldolase
A0U92_RS00775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A0U92_RS00790	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A0U92_RS00795	COG0081	regulation of translation
A0U92_RS00800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A0U92_RS00805	COG0222	ribosome binding
A0U92_RS00810	COG0085	RNA polymerase activity
A0U92_RS00815	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A0U92_RS00820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A0U92_RS00825	COG0049	tRNA binding
A0U92_RS00830	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A0U92_RS00835	COG0051	transcription antitermination factor activity, RNA binding
A0U92_RS00840	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A0U92_RS00845	COG0088	Forms part of the polypeptide exit tunnel
A0U92_RS00850	COG0089	rRNA binding
A0U92_RS00855	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A0U92_RS00860	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A0U92_RS00865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A0U92_RS00870	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A0U92_RS00875	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A0U92_RS00880	COG0255	Belongs to the universal ribosomal protein uL29 family
A0U92_RS00885	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A0U92_RS00890	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A0U92_RS00895	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A0U92_RS00900	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A0U92_RS00905	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A0U92_RS00910	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A0U92_RS00915	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A0U92_RS00920	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A0U92_RS00925	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A0U92_RS00930	COG1841	ribosomal large subunit assembly
A0U92_RS00935	COG0200	Binds to the 23S rRNA
A0U92_RS00940	COG0201	protein transport
A0U92_RS00945	COG0563	adenylate kinase activity
A0U92_RS00950	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A0U92_RS00955	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A0U92_RS00960	COG0202	RNA polymerase activity
A0U92_RS00965	COG0203	ribosomal protein L17
A0U92_RS00980	COG1116	anion transmembrane transporter activity
A0U92_RS00990	COG5487	UPF0391 membrane protein
A0U92_RS01010	COG0159	tryptophan synthase activity
A0U92_RS01015	COG0133	tryptophan synthase activity
A0U92_RS01020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A0U92_RS01040	COG0583	DNA-binding transcription factor activity
A0U92_RS01060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A0U92_RS01060	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A0U92_RS01065	COG0194	GDP metabolic process
A0U92_RS01070	COG0300	oxidoreductase activity
A0U92_RS01075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A0U92_RS01180	COG0564	pseudouridine synthase activity
A0U92_RS01190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A0U92_RS01195	COG0667	Aldo Keto reductase
A0U92_RS01200	COG1420	regulation of RNA biosynthetic process
A0U92_RS01235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A0U92_RS01250	COG0469	pyruvate kinase activity
A0U92_RS01255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A0U92_RS01260	COG0351	phosphomethylpyrimidine kinase
A0U92_RS01260	COG0352	thiamine-phosphate diphosphorylase activity
A0U92_RS01265	COG0745	RESPONSE REGULATOR receiver
A0U92_RS01280	COG0802	atpase or kinase
A0U92_RS01285	COG2887	Belongs to the helicase family. UvrD subfamily
A0U92_RS01290	COG1074	ATP-dependent DNA helicase activity
A0U92_RS01310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A0U92_RS01315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A0U92_RS01325	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0U92_RS01330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A0U92_RS01345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A0U92_RS01365	COG0560	Phosphoserine phosphatase
A0U92_RS01365	COG3830	Belongs to the UPF0237 family
A0U92_RS01370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A0U92_RS01375	COG0028	Belongs to the TPP enzyme family
A0U92_RS01385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A0U92_RS01430	COG0167	dihydroorotate dehydrogenase activity
A0U92_RS01440	COG3128	pkhd-type hydroxylase
A0U92_RS01445	COG4774	siderophore transport
A0U92_RS01460	COG0848	biopolymer transport protein
A0U92_RS01480	COG3842	ATPase activity
A0U92_RS01485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A0U92_RS01490	COG1176	ABC-type spermidine putrescine transport system, permease component I
A0U92_RS01495	COG1177	transmembrane transport
A0U92_RS01500	COG0583	DNA-binding transcription factor activity
A0U92_RS01505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A0U92_RS01525	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A0U92_RS01535	COG0303	'Molybdopterin
A0U92_RS01540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A0U92_RS01550	COG0148	phosphopyruvate hydratase activity
A0U92_RS01565	COG3660	Nucleoside-diphosphate-sugar epimerase
A0U92_RS01600	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
A0U92_RS01610	COG0232	Belongs to the dGTPase family. Type 2 subfamily
A0U92_RS01620	COG0531	amino acid
A0U92_RS01625	COG4302	ethanolamine ammonia-lyase activity
A0U92_RS01630	COG4303	Ethanolamine ammonia lyase large subunit
A0U92_RS01640	COG1942	4-Oxalocrotonate Tautomerase
A0U92_RS01645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A0U92_RS01665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A0U92_RS01675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0U92_RS01680	COG0347	Belongs to the P(II) protein family
A0U92_RS01705	COG0228	four-way junction DNA binding
A0U92_RS01710	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A0U92_RS01715	COG0336	Belongs to the RNA methyltransferase TrmD family
A0U92_RS01720	COG0335	large ribosomal subunit rRNA binding
A0U92_RS01735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A0U92_RS01745	COG0745	RESPONSE REGULATOR receiver
A0U92_RS01755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A0U92_RS01760	COG0581	inorganic phosphate transmembrane transporter activity
A0U92_RS01770	COG3042	response to heat
A0U92_RS01785	COG0312	modulator of DNA gyrase
A0U92_RS01790	COG0612	Peptidase, M16
A0U92_RS01805	COG0443	Heat shock 70 kDa protein
A0U92_RS01810	COG2203	Gaf domain
A0U92_RS01810	COG3706	GGDEF domain
A0U92_RS01810	COG4251	negative regulation of phosphorylation
A0U92_RS01810	COG5001	Diguanylate cyclase
A0U92_RS01815	COG3511	phospholipase C
A0U92_RS01830	COG1032	radical SAM domain protein
A0U92_RS01840	COG0066	3-isopropylmalate dehydratase activity
A0U92_RS01845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A0U92_RS01865	COG1573	uracil-dna glycosylase
A0U92_RS01870	COG0741	lytic transglycosylase activity
A0U92_RS01885	COG0489	protein tyrosine kinase activity
A0U92_RS01905	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A0U92_RS01930	COG1612	heme a metabolic process
A0U92_RS01940	COG2814	Major facilitator Superfamily
A0U92_RS01950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A0U92_RS01955	COG1289	transmembrane transporter activity
A0U92_RS01970	COG0473	3-isopropylmalate dehydrogenase activity
A0U92_RS01975	COG2818	Glycosylase
A0U92_RS02000	COG1217	gtp-binding protein TYPA
A0U92_RS02045	COG0126	phosphoglycerate kinase activity
A0U92_RS02070	COG0156	8-amino-7-oxononanoate synthase activity
A0U92_RS02080	COG2733	membrane
A0U92_RS02090	COG1959	2 iron, 2 sulfur cluster binding
A0U92_RS02095	COG0719	Fe-S assembly protein
A0U92_RS02100	COG0396	ATPase activity
A0U92_RS02105	COG0719	Fe-S assembly protein
A0U92_RS02110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A0U92_RS02120	COG2151	metal-sulfur cluster biosynthetic enzyme
A0U92_RS02125	COG0316	Belongs to the HesB IscA family
A0U92_RS02140	COG1309	transcriptional regulator
A0U92_RS02165	COG2010	Cytochrome c
A0U92_RS02175	COG1028	Short-chain dehydrogenase reductase Sdr
A0U92_RS02195	COG2130	NADP-dependent
A0U92_RS02220	COG0583	DNA-binding transcription factor activity
A0U92_RS02265	COG1678	Uncharacterized ACR, COG1678
A0U92_RS02270	COG4221	oxidoreductase activity
A0U92_RS02275	COG2326	polyphosphate kinase activity
A0U92_RS02285	COG0583	DNA-binding transcription factor activity
A0U92_RS02310	COG1597	lipid kinase activity
A0U92_RS02325	COG1671	Belongs to the UPF0178 family
A0U92_RS02330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A0U92_RS02340	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
A0U92_RS02350	COG4786	Flagellar basal body rod
A0U92_RS02365	COG0778	Nitroreductase
A0U92_RS02370	COG0477	Major facilitator Superfamily
A0U92_RS02385	COG0004	ammonium transporteR
A0U92_RS02395	COG0069	glutamate synthase activity
A0U92_RS02400	COG2218	PFAM glutamate synthase alpha subunit domain protein
A0U92_RS02405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A0U92_RS02420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0U92_RS02425	COG4311	Sarcosine oxidase, delta subunit
A0U92_RS02430	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0U92_RS02430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A0U92_RS02445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A0U92_RS02455	COG4303	Ethanolamine ammonia lyase large subunit
A0U92_RS02465	COG4176	ABC-type proline glycine betaine transport system permease component
A0U92_RS02470	COG4175	Glycine betaine
A0U92_RS02470	COG3448	diguanylate cyclase activity
A0U92_RS02475	COG2113	Glycine betaine
A0U92_RS02490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A0U92_RS02500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A0U92_RS02510	COG1301	dicarboxylic acid transport
A0U92_RS02515	COG1322	Protein conserved in bacteria
A0U92_RS02520	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A0U92_RS02535	COG1285	pathogenesis
A0U92_RS02540	COG4191	Histidine kinase
A0U92_RS02545	COG4566	intracellular signal transduction
A0U92_RS02595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0U92_RS02600	COG2368	4-hydroxyphenylacetate
A0U92_RS02625	COG4638	Rieske (2fe-2S)
A0U92_RS02640	COG0154	amidase activity
A0U92_RS02650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A0U92_RS02670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0U92_RS02680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0U92_RS02690	COG1012	belongs to the aldehyde dehydrogenase family
A0U92_RS02705	COG4638	Rieske (2fe-2S)
A0U92_RS02745	COG0583	DNA-binding transcription factor activity
A0U92_RS02770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0U92_RS02770	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0U92_RS02775	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A0U92_RS02780	COG3422	double-strand break repair
A0U92_RS02880	COG3177	Filamentation induced by cAMP protein fic
A0U92_RS02890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A0U92_RS02985	COG2983	Belongs to the UPF0260 family
A0U92_RS03015	COG2755	lipolytic protein G-D-S-L family
A0U92_RS03015	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A0U92_RS03030	COG0492	ferredoxin-NADP+ reductase activity
A0U92_RS03035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A0U92_RS03040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0U92_RS03050	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A0U92_RS03050	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A0U92_RS03050	COG0506	proline dehydrogenase activity
A0U92_RS03055	COG0655	NAD(P)H dehydrogenase (quinone) activity
A0U92_RS03070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A0U92_RS03080	COG0625	glutathione transferase activity
A0U92_RS03095	COG2249	NAD(P)H dehydrogenase (quinone) activity
A0U92_RS03170	COG0667	Aldo Keto reductase
A0U92_RS03175	COG1228	amidohydrolase
A0U92_RS03185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0U92_RS03185	COG1116	anion transmembrane transporter activity
A0U92_RS03210	COG0583	DNA-binding transcription factor activity
A0U92_RS03215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0U92_RS03220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0U92_RS03250	COG1116	anion transmembrane transporter activity
A0U92_RS03255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0U92_RS03260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0U92_RS03265	COG1960	acyl-CoA dehydrogenase activity
A0U92_RS03305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0U92_RS03310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0U92_RS03320	COG1609	Transcriptional regulator
A0U92_RS03325	COG2271	Major facilitator Superfamily
A0U92_RS03330	COG3265	gluconokinase activity
A0U92_RS03335	COG0129	dihydroxy-acid dehydratase activity
A0U92_RS03340	COG0800	Aldolase
A0U92_RS03355	COG4993	Dehydrogenase
A0U92_RS03600	COG0616	signal peptide processing
A0U92_RS03640	COG4386	tail sheath protein
A0U92_RS03685	COG3778	Protein conserved in bacteria
A0U92_RS03750	COG0740	serine-type endopeptidase activity
A0U92_RS03760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A0U92_RS03765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A0U92_RS03770	COG1766	The M ring may be actively involved in energy transduction
A0U92_RS03775	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A0U92_RS03785	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A0U92_RS03790	COG2204	response regulator
A0U92_RS03795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A0U92_RS03805	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A0U92_RS03810	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A0U92_RS03815	COG1137	ATPase activity
A0U92_RS03870	COG3525	Glycosyl hydrolase, family 20, catalytic domain
A0U92_RS03880	COG0101	tRNA pseudouridine synthase activity
A0U92_RS03885	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A0U92_RS03890	COG0242	peptide deformylase activity
A0U92_RS03920	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A0U92_RS03945	COG4774	siderophore transport
A0U92_RS03955	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
A0U92_RS03970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
A0U92_RS03975	COG0574	Belongs to the PEP-utilizing enzyme family
A0U92_RS03975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A0U92_RS03980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A0U92_RS03985	COG0497	DNA recombination
A0U92_RS03990	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A0U92_RS04005	COG0849	cell division
A0U92_RS04015	COG1181	Belongs to the D-alanine--D-alanine ligase family
A0U92_RS04020	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A0U92_RS04025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A0U92_RS04030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A0U92_RS04040	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A0U92_RS04045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A0U92_RS04050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A0U92_RS04055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A0U92_RS04070	COG0275	rRNA processing
A0U92_RS04075	COG2001	Belongs to the MraZ family
A0U92_RS04095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0U92_RS04100	COG4774	siderophore transport
A0U92_RS04105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A0U92_RS04110	COG0110	maltose O-acetyltransferase activity
A0U92_RS04115	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A0U92_RS04120	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A0U92_RS04130	COG0047	phosphoribosylformylglycinamidine synthase activity
A0U92_RS04135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A0U92_RS04140	COG0271	Belongs to the BolA IbaG family
A0U92_RS04145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A0U92_RS04155	COG0792	nuclease activity
A0U92_RS04160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A0U92_RS04165	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A0U92_RS04170	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A0U92_RS04175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A0U92_RS04180	COG3541	Predicted nucleotidyltransferase
A0U92_RS04190	COG0138	bifunctional purine biosynthesis protein purh
A0U92_RS04195	COG0439	Biotin carboxylase
A0U92_RS04200	COG0511	ligase activity, forming carbon-carbon bonds
A0U92_RS04205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A0U92_RS04210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A0U92_RS04215	COG1295	ribonuclease BN
A0U92_RS04225	COG0521	Mo-molybdopterin cofactor biosynthetic process
A0U92_RS04255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0U92_RS04265	COG0181	hydroxymethylbilane synthase activity
A0U92_RS04270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A0U92_RS04295	COG0583	DNA-binding transcription factor activity
A0U92_RS04305	COG0004	ammonium transporteR
A0U92_RS04330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0U92_RS04335	COG0840	transmembrane signaling receptor activity
A0U92_RS04340	COG0784	Response regulator, receiver
A0U92_RS04340	COG0643	Histidine kinase
A0U92_RS04340	COG2198	Histidine kinase
A0U92_RS04345	COG2198	Histidine kinase
A0U92_RS04345	COG0643	Histidine kinase
A0U92_RS04350	COG0835	chemotaxis
A0U92_RS04355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A0U92_RS04360	COG2201	protein-glutamate methylesterase activity
A0U92_RS04365	COG0745	RESPONSE REGULATOR receiver
A0U92_RS04370	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
A0U92_RS04380	COG0488	(ABC) transporter
A0U92_RS04385	COG0105	UTP biosynthetic process
A0U92_RS04400	COG2706	6-phosphogluconolactonase activity
A0U92_RS04405	COG0281	malic enzyme
A0U92_RS04415	COG0215	cysteine-tRNA ligase activity
A0U92_RS04450	COG0438	transferase activity, transferring glycosyl groups
A0U92_RS04490	COG5492	domain, Protein
A0U92_RS04490	COG1621	beta-fructofuranosidase activity
A0U92_RS04490	COG3583	domain protein
A0U92_RS04515	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0U92_RS04515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A0U92_RS04525	COG1760	l-serine dehydratase
A0U92_RS04545	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0U92_RS04545	COG1902	pentaerythritol trinitrate reductase activity
A0U92_RS04550	COG0247	lactate metabolic process
A0U92_RS04550	COG2181	nitrate reductase activity
A0U92_RS04565	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A0U92_RS04570	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A0U92_RS04615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A0U92_RS04620	COG3153	acetyltransferase
A0U92_RS04620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0U92_RS04635	COG1012	belongs to the aldehyde dehydrogenase family
A0U92_RS04640	COG4176	ABC-type proline glycine betaine transport system permease component
A0U92_RS04645	COG4175	Glycine betaine
A0U92_RS04670	COG4774	siderophore transport
A0U92_RS04685	COG1113	amino acid transport
A0U92_RS04690	COG3588	fructose-bisphosphate aldolase
A0U92_RS04695	COG3961	Belongs to the TPP enzyme family
A0U92_RS04700	COG0247	lactate metabolic process
A0U92_RS04705	COG1139	Iron-sulfur cluster binding protein
A0U92_RS04740	COG0052	Belongs to the universal ribosomal protein uS2 family
A0U92_RS04745	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A0U92_RS04750	COG1381	Involved in DNA repair and RecF pathway recombination
A0U92_RS04765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A0U92_RS04790	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A0U92_RS04790	COG3261	NADH dehydrogenase
A0U92_RS04795	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0U92_RS04805	COG0688	phosphatidylethanolamine metabolic process
A0U92_RS04820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0U92_RS04845	COG2884	Cell division ATP-binding protein ftsE
A0U92_RS04865	COG2081	HI0933 family
A0U92_RS04870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A0U92_RS04875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A0U92_RS04885	COG0628	permease
A0U92_RS04890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A0U92_RS04895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A0U92_RS04910	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A0U92_RS04915	COG1127	ABC transporter
A0U92_RS04920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0U92_RS04925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A0U92_RS04945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A0U92_RS04950	COG0583	DNA-binding transcription factor activity
A0U92_RS04955	COG4771	TonB-dependent receptor
A0U92_RS04970	COG0668	transmembrane transport
A0U92_RS04975	COG1714	RDD family
A0U92_RS04980	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A0U92_RS04985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A0U92_RS04990	COG0653	protein targeting
A0U92_RS04995	COG0217	transcriptional regulatory protein
A0U92_RS05010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A0U92_RS05025	COG2877	3-deoxy-8-phosphooctulonate synthase activity
A0U92_RS05030	COG0504	CTP synthase activity
A0U92_RS05040	COG0149	triose-phosphate isomerase activity
A0U92_RS05055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A0U92_RS05060	COG0633	Ferredoxin
A0U92_RS05060	COG3217	Mosc domain protein beta barrel domain protein
A0U92_RS05065	COG0306	phosphate transporter
A0U92_RS05090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0U92_RS05115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A0U92_RS05120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A0U92_RS05125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A0U92_RS05140	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A0U92_RS05155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A0U92_RS05195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A0U92_RS05200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A0U92_RS05205	COG4206	TonB-dependent receptor
A0U92_RS05215	COG0583	DNA-binding transcription factor activity
A0U92_RS05235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A0U92_RS05240	COG0830	nickel cation binding
A0U92_RS05250	COG0804	urea catabolic process
A0U92_RS05255	COG0832	Belongs to the urease beta subunit family
A0U92_RS05260	COG0831	urea catabolic process
A0U92_RS05265	COG0829	nickel cation binding
A0U92_RS05280	COG0358	DNA primase activity
A0U92_RS05285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A0U92_RS05295	COG0360	Binds together with S18 to 16S ribosomal RNA
A0U92_RS05300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A0U92_RS05305	COG0359	binds to the 23S rRNA
A0U92_RS05310	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A0U92_RS05315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0U92_RS05320	COG0527	aspartate kinase activity
A0U92_RS05325	COG2070	2-Nitropropane dioxygenase
A0U92_RS05335	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A0U92_RS05340	COG0124	histidyl-tRNA synthetase
A0U92_RS05345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A0U92_RS05390	COG1530	ribonuclease E activity
A0U92_RS05395	COG0556	nucleotide-excision repair
A0U92_RS05400	COG5001	Diguanylate cyclase
A0U92_RS05400	COG3300	MHYT domain
A0U92_RS05405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A0U92_RS05410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A0U92_RS05425	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A0U92_RS05440	COG4558	Periplasmic binding protein
A0U92_RS05445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0U92_RS05450	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A0U92_RS05460	COG1028	Short-chain dehydrogenase reductase Sdr
A0U92_RS05465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0U92_RS05485	COG3293	Transposase
A0U92_RS05490	COG2353	YceI-like domain
A0U92_RS05495	COG3384	dioxygenase
A0U92_RS05500	COG0583	DNA-binding transcription factor activity
A0U92_RS05515	COG0259	pyridoxamine-phosphate oxidase activity
A0U92_RS05520	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A0U92_RS05525	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A0U92_RS05530	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A0U92_RS05535	COG0604	alcohol dehydrogenase
A0U92_RS05555	COG1902	pentaerythritol trinitrate reductase activity
A0U92_RS05570	COG4974	Belongs to the 'phage' integrase family
A0U92_RS05580	COG0745	RESPONSE REGULATOR receiver
A0U92_RS05585	COG5002	protein histidine kinase activity
A0U92_RS05585	COG0784	Response regulator, receiver
A0U92_RS05585	COG2198	Histidine kinase
A0U92_RS05595	COG0559	Belongs to the binding-protein-dependent transport system permease family
A0U92_RS05605	COG0411	ABC transporter
A0U92_RS05625	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A0U92_RS05630	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A0U92_RS05645	COG0742	ribosomal rna small subunit methyltransferase
A0U92_RS05650	COG1187	pseudouridine synthase activity
A0U92_RS05655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A0U92_RS05660	COG0590	tRNA wobble adenosine to inosine editing
A0U92_RS05665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0U92_RS05700	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A0U92_RS05715	COG0840	transmembrane signaling receptor activity
A0U92_RS05730	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A0U92_RS05730	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A0U92_RS05745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A0U92_RS05750	COG0564	pseudouridine synthase activity
A0U92_RS05780	COG0513	Belongs to the DEAD box helicase family
A0U92_RS05795	COG2814	Major facilitator Superfamily
A0U92_RS05805	COG0477	Major facilitator Superfamily
A0U92_RS05810	COG4993	Dehydrogenase
A0U92_RS05820	COG0114	fumarate hydratase activity
A0U92_RS05830	COG0840	transmembrane signaling receptor activity
A0U92_RS05835	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A0U92_RS05845	COG4774	siderophore transport
A0U92_RS05865	COG1663	tetraacyldisaccharide 4'-kinase activity
A0U92_RS05870	COG1519	Transferase
A0U92_RS05875	COG1012	belongs to the aldehyde dehydrogenase family
A0U92_RS05905	COG1028	Short-chain dehydrogenase reductase Sdr
A0U92_RS05915	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0U92_RS05925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A0U92_RS05930	COG4208	sulfate ABC transporter
A0U92_RS05935	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A0U92_RS05970	COG1045	serine acetyltransferase
A0U92_RS05980	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A0U92_RS05995	COG1177	transmembrane transport
A0U92_RS06025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0U92_RS06030	COG0747	negative chemotaxis
A0U92_RS06040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A0U92_RS06040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A0U92_RS06080	COG1028	Short-chain dehydrogenase reductase Sdr
A0U92_RS06105	COG1160	GTP binding
A0U92_RS06130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0U92_RS06135	COG1393	Belongs to the ArsC family
A0U92_RS06140	COG1278	Cold shock
A0U92_RS06185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0U92_RS06195	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A0U92_RS06195	COG3608	succinylglutamate desuccinylase aspartoacylase
A0U92_RS06200	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A0U92_RS06200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A0U92_RS06210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A0U92_RS06215	COG0402	S-adenosylhomocysteine deaminase activity
A0U92_RS06225	COG0850	regulation of cytokinetic process
A0U92_RS06230	COG2894	cell division
A0U92_RS06235	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
A0U92_RS06245	COG1764	response to oxidative stress
A0U92_RS06265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A0U92_RS06280	COG3590	peptidase
A0U92_RS06310	COG0463	Glycosyl transferase, family 2
A0U92_RS06315	COG0398	Pfam SNARE associated Golgi protein
A0U92_RS06325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A0U92_RS06335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A0U92_RS06340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A0U92_RS06360	COG0535	radical SAM domain protein
A0U92_RS06370	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
A0U92_RS06375	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A0U92_RS06400	COG2995	paraquat-inducible protein a
A0U92_RS06425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0U92_RS06430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0U92_RS06445	COG2189	Belongs to the N(4) N(6)-methyltransferase family
A0U92_RS06450	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A0U92_RS06460	COG0477	Major facilitator Superfamily
A0U92_RS06470	COG1793	dna ligase
A0U92_RS06480	COG1201	RNA secondary structure unwinding
A0U92_RS06495	COG0752	glycyl-tRNA synthetase alpha subunit
A0U92_RS06505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A0U92_RS06510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0U92_RS06515	COG0525	valine-tRNA ligase activity
A0U92_RS06535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A0U92_RS06545	COG0837	glucose binding
A0U92_RS06550	COG4221	oxidoreductase activity
A0U92_RS06555	COG0456	acetyltransferase
A0U92_RS06570	COG1566	PFAM secretion protein HlyD family protein
A0U92_RS06590	COG2132	Multicopper oxidase
A0U92_RS06615	COG4964	Belongs to the GSP D family
A0U92_RS06680	COG0714	Associated with various cellular activities
A0U92_RS06690	COG0617	tRNA 3'-terminal CCA addition
A0U92_RS06695	COG1132	(ABC) transporter
A0U92_RS06700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A0U92_RS06705	COG2264	protein methyltransferase activity
A0U92_RS06710	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0U92_RS06715	COG0154	amidase activity
A0U92_RS06720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0U92_RS06725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A0U92_RS06735	COG2199	diguanylate cyclase activity
A0U92_RS06740	COG2171	N-acyltransferase activity
A0U92_RS06745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A0U92_RS06755	COG0438	transferase activity, transferring glycosyl groups
A0U92_RS06765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A0U92_RS06780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A0U92_RS06780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A0U92_RS06805	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A0U92_RS06815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0U92_RS06820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A0U92_RS06825	COG0372	Belongs to the citrate synthase family
A0U92_RS06830	COG2079	MmgE PrpD family protein
A0U92_RS06835	COG1396	sequence-specific DNA binding
A0U92_RS06835	COG3800	Transcriptional regulator
A0U92_RS06855	COG1858	cytochrome C peroxidase
A0U92_RS06875	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
A0U92_RS06895	COG0606	chelatase, subunit chli
A0U92_RS06900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0U92_RS06905	COG0483	inositol monophosphate 1-phosphatase activity
A0U92_RS06910	COG3474	cytochrome
A0U92_RS06915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
A0U92_RS06920	COG0077	Prephenate dehydratase
A0U92_RS06920	COG1605	Chorismate mutase
A0U92_RS06925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A0U92_RS06930	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A0U92_RS06935	COG1278	Cold shock
A0U92_RS06960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A0U92_RS06965	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A0U92_RS06970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A0U92_RS06975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A0U92_RS06990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A0U92_RS07000	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A0U92_RS07005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A0U92_RS07010	COG1196	nuclear chromosome segregation
A0U92_RS07010	COG0741	lytic transglycosylase activity
A0U92_RS07010	COG0739	heme binding
A0U92_RS07015	COG0861	Integral membrane protein TerC family
A0U92_RS07030	COG1648	precorrin-2 dehydrogenase activity
A0U92_RS07030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A0U92_RS07035	COG5328	Belongs to the UPF0262 family
A0U92_RS07055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A0U92_RS07060	COG0134	indole-3-glycerol-phosphate synthase activity
A0U92_RS07075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A0U92_RS07080	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0U92_RS07080	COG0022	dehydrogenase e1 component
A0U92_RS07085	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0U92_RS07090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A0U92_RS07110	COG0697	spore germination
A0U92_RS07115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0U92_RS07120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A0U92_RS07125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A0U92_RS07135	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A0U92_RS07145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A0U92_RS07190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A0U92_RS07195	COG1459	type II secretion system
A0U92_RS07250	COG3511	phospholipase C
A0U92_RS07305	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A0U92_RS07335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A0U92_RS07400	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
A0U92_RS07410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A0U92_RS07415	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A0U92_RS07420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A0U92_RS07445	COG1289	transmembrane transporter activity
A0U92_RS07460	COG0539	negative regulation of cytoplasmic translation
A0U92_RS07480	COG0019	diaminopimelate decarboxylase activity
A0U92_RS07500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A0U92_RS07520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A0U92_RS07525	COG0295	cytidine deaminase activity
A0U92_RS07535	COG1584	GPR1 FUN34 yaaH family protein
A0U92_RS07550	COG1132	(ABC) transporter
A0U92_RS07555	COG0438	transferase activity, transferring glycosyl groups
A0U92_RS07565	COG0432	Pfam Uncharacterised protein family UPF0047
A0U92_RS07595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A0U92_RS07610	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A0U92_RS07630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A0U92_RS07650	COG0356	it plays a direct role in the translocation of protons across the membrane
A0U92_RS07655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A0U92_RS07660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A0U92_RS07665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A0U92_RS07670	COG0463	Glycosyl transferase, family 2
A0U92_RS07675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A0U92_RS07695	COG3293	Transposase
A0U92_RS07715	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A0U92_RS07715	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A0U92_RS07720	COG1494	fructose-1,6-bisphosphatase
A0U92_RS07730	COG0436	Aminotransferase
A0U92_RS07740	COG2271	Major facilitator Superfamily
A0U92_RS07765	COG0390	transport system, permease component
A0U92_RS07770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A0U92_RS07790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A0U92_RS07795	COG0237	dephospho-CoA kinase activity
A0U92_RS07825	COG0321	lipoyl(octanoyl) transferase activity
A0U92_RS07850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A0U92_RS07880	COG1573	uracil-dna glycosylase
A0U92_RS07900	COG0175	sulfate reduction
A0U92_RS07905	COG0175	sulfate reduction
A0U92_RS07915	COG2226	methyltransferase
A0U92_RS07925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A0U92_RS07955	COG1304	FMN binding
A0U92_RS07970	COG0745	RESPONSE REGULATOR receiver
A0U92_RS07995	COG0457	Tetratricopeptide repeat
A0U92_RS07995	COG0859	PFAM glycosyl transferase family 9
A0U92_RS08000	COG0659	secondary active sulfate transmembrane transporter activity
A0U92_RS08015	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A0U92_RS08030	COG0534	Mate efflux family protein
A0U92_RS08050	COG1706	bacterial-type flagellum-dependent cell motility
A0U92_RS08070	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A0U92_RS08105	COG2999	glutathione oxidoreductase activity
A0U92_RS08110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A0U92_RS08115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0U92_RS08120	COG1127	ABC transporter
A0U92_RS08125	COG3008	intermembrane lipid transfer
A0U92_RS08125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A0U92_RS08140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0U92_RS08155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A0U92_RS08160	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A0U92_RS08165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0U92_RS08175	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A0U92_RS08185	COG0793	Belongs to the peptidase S41A family
A0U92_RS08195	COG1051	belongs to the nudix hydrolase family
A0U92_RS08210	COG0438	transferase activity, transferring glycosyl groups
A0U92_RS08230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A0U92_RS08250	COG0045	succinate-CoA ligase (ADP-forming) activity
A0U92_RS08255	COG0604	alcohol dehydrogenase
A0U92_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
A0U92_RS08255	COG3321	synthase
A0U92_RS08260	COG0596	Alpha beta hydrolase
A0U92_RS08270	COG2719	SpoVR family
A0U92_RS08275	COG2718	Belongs to the UPF0229 family
A0U92_RS08280	COG2766	serine protein kinase
A0U92_RS08290	COG0084	hydrolase, TatD family'
A0U92_RS08295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0U92_RS08305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A0U92_RS08310	COG1686	Belongs to the peptidase S11 family
A0U92_RS08315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A0U92_RS08320	COG2951	lytic endotransglycosylase activity
A0U92_RS08345	COG1968	undecaprenyl-diphosphatase activity
A0U92_RS08350	COG0531	amino acid
A0U92_RS08365	COG0165	Argininosuccinate lyase
A0U92_RS08370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A0U92_RS08375	COG3585	molybdate ion transport
A0U92_RS08380	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A0U92_RS08385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A0U92_RS08405	COG1113	amino acid transport
A0U92_RS08410	COG1396	sequence-specific DNA binding
A0U92_RS08410	COG3800	Transcriptional regulator
A0U92_RS08415	COG2224	Isocitrate lyase
A0U92_RS08420	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A0U92_RS08425	COG1380	Effector of murein hydrolase LrgA
A0U92_RS08430	COG1346	cytolysis
A0U92_RS08440	COG1970	mechanosensitive ion channel activity
A0U92_RS08445	COG0254	rRNA binding
A0U92_RS08470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A0U92_RS08485	COG0494	nUDIX hydrolase
A0U92_RS08490	COG2814	Major facilitator Superfamily
A0U92_RS08495	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
A0U92_RS08500	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A0U92_RS08520	COG1215	transferase activity, transferring glycosyl groups
A0U92_RS08535	COG0271	Belongs to the BolA IbaG family
A0U92_RS08540	COG0484	heat shock protein binding
A0U92_RS08555	COG0076	glutamate decarboxylase activity
A0U92_RS08560	COG0596	Alpha beta hydrolase
A0U92_RS08570	COG2308	Evidence 4 Homologs of previously reported genes of
A0U92_RS08580	COG2003	Belongs to the UPF0758 family
A0U92_RS08585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A0U92_RS08590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A0U92_RS08595	COG0546	phosphoglycolate phosphatase activity
A0U92_RS08625	COG0697	spore germination
A0U92_RS08630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A0U92_RS08635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A0U92_RS08640	COG0546	phosphoglycolate phosphatase activity
A0U92_RS08650	COG1692	metallophosphoesterase
A0U92_RS08655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A0U92_RS08680	COG0352	thiamine-phosphate diphosphorylase activity
A0U92_RS08685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A0U92_RS08710	COG2308	Evidence 4 Homologs of previously reported genes of
A0U92_RS08710	COG2307	Protein conserved in bacteria
A0U92_RS08735	COG4993	Dehydrogenase
A0U92_RS08740	COG4993	Dehydrogenase
A0U92_RS08795	COG1862	Preprotein translocase
A0U92_RS08810	COG0494	nUDIX hydrolase
A0U92_RS08815	COG1546	Belongs to the CinA family
A0U92_RS08815	COG1058	Belongs to the CinA family
A0U92_RS08820	COG0825	malonyl-CoA metabolic process
A0U92_RS08825	COG4974	Belongs to the 'phage' integrase family
A0U92_RS08835	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A0U92_RS08840	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A0U92_RS08840	COG2885	chlorophyll binding
A0U92_RS08850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A0U92_RS08865	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
A0U92_RS08870	COG1509	lysine 2,3-aminomutase activity
A0U92_RS08880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A0U92_RS08885	COG1196	nuclear chromosome segregation
A0U92_RS08900	COG0459	protein refolding
A0U92_RS08905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A0U92_RS08910	COG0583	DNA-binding transcription factor activity
A0U92_RS08925	COG2814	Major facilitator Superfamily
A0U92_RS08945	COG0037	tRNA processing
A0U92_RS08955	COG2885	chlorophyll binding
A0U92_RS08960	COG0823	Involved in the tonB-independent uptake of proteins
A0U92_RS08970	COG0848	biopolymer transport protein
A0U92_RS08980	COG0824	Thioesterase
A0U92_RS08985	COG2255	four-way junction helicase activity
A0U92_RS08990	COG0632	four-way junction helicase activity
A0U92_RS08995	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A0U92_RS09010	COG1607	acyl-coa hydrolase
A0U92_RS09030	COG1929	Belongs to the glycerate kinase type-1 family
A0U92_RS09040	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A0U92_RS09045	COG1605	Chorismate mutase
A0U92_RS09045	COG0287	Prephenate dehydrogenase
A0U92_RS09050	COG2062	phosphohistidine phosphatase, SixA
A0U92_RS09080	COG1450	Type ii and iii secretion system protein
A0U92_RS09095	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A0U92_RS09100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A0U92_RS09115	COG0142	geranyltranstransferase activity
A0U92_RS09130	COG0783	Belongs to the Dps family
A0U92_RS09140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A0U92_RS09145	COG0583	DNA-binding transcription factor activity
A0U92_RS09150	COG0450	alkyl hydroperoxide reductase
A0U92_RS09155	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A0U92_RS09180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A0U92_RS09185	COG1923	regulation of RNA biosynthetic process
A0U92_RS09190	COG2204	response regulator
A0U92_RS09240	COG0717	Belongs to the dCTP deaminase family
A0U92_RS09245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A0U92_RS09250	COG0657	acetylesterase activity
A0U92_RS09290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0U92_RS09310	COG2967	ApaG domain
A0U92_RS09315	COG0302	gtp cyclohydrolase
A0U92_RS09325	COG0187	DNA topoisomerase II activity
A0U92_RS09345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A0U92_RS09350	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A0U92_RS09350	COG2885	chlorophyll binding
A0U92_RS09360	COG0793	Belongs to the peptidase S41A family
A0U92_RS09365	COG0557	exoribonuclease II activity
A0U92_RS09370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A0U92_RS09375	COG0758	DNA mediated transformation
A0U92_RS09380	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A0U92_RS09385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A0U92_RS09390	COG0540	Belongs to the ATCase OTCase family
A0U92_RS09395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0U92_RS09400	COG1289	transmembrane transporter activity
A0U92_RS09405	COG0583	DNA-binding transcription factor activity
A0U92_RS09420	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A0U92_RS09425	COG1674	ftsk spoiiie
A0U92_RS09430	COG0564	pseudouridine synthase activity
A0U92_RS09450	COG2022	thiamine diphosphate biosynthetic process
A0U92_RS09485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A0U92_RS09495	COG1185	polyribonucleotide nucleotidyltransferase activity
A0U92_RS09505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A0U92_RS09510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A0U92_RS09515	COG1196	nuclear chromosome segregation
A0U92_RS09515	COG0739	heme binding
A0U92_RS09515	COG0741	lytic transglycosylase activity
A0U92_RS09525	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A0U92_RS09530	COG1686	Belongs to the peptidase S11 family
A0U92_RS09535	COG2890	protein-(glutamine-N5) methyltransferase activity
A0U92_RS09545	COG0277	FAD linked oxidase domain protein
A0U92_RS09575	COG1999	signal sequence binding
A0U92_RS09605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A0U92_RS09610	COG1702	phosphate starvation-inducible protein PhoH
A0U92_RS09615	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A0U92_RS09635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A0U92_RS09650	COG0746	molybdenum cofactor guanylyltransferase activity
A0U92_RS09650	COG0315	cyclic pyranopterin monophosphate synthase activity
A0U92_RS09660	COG0243	molybdopterin cofactor binding
A0U92_RS09675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A0U92_RS09685	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A0U92_RS09690	COG0268	Binds directly to 16S ribosomal RNA
A0U92_RS09695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A0U92_RS09700	COG2226	methyltransferase
A0U92_RS09710	COG0756	dUTP diphosphatase activity
A0U92_RS09720	COG1116	anion transmembrane transporter activity
A0U92_RS09730	COG0612	Peptidase, M16
A0U92_RS09735	COG1028	Short-chain dehydrogenase reductase Sdr
A0U92_RS09740	COG3264	Mechanosensitive ion channel
A0U92_RS09740	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
A0U92_RS09745	COG1297	OPT oligopeptide transporter protein
A0U92_RS09760	COG2217	Heavy metal translocating P-type atpase
A0U92_RS09780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0U92_RS09785	COG1621	beta-fructofuranosidase activity
A0U92_RS09825	COG1414	Transcriptional regulator
A0U92_RS09830	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A0U92_RS09835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A0U92_RS09850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A0U92_RS09870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A0U92_RS09875	COG5373	membrane
A0U92_RS09875	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A0U92_RS09890	COG0779	Required for maturation of 30S ribosomal subunits
A0U92_RS09900	COG0542	response to heat
A0U92_RS09910	COG0583	DNA-binding transcription factor activity
A0U92_RS09915	COG0765	amino acid transport
A0U92_RS09920	COG1126	abc transporter atp-binding protein
A0U92_RS09925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A0U92_RS09930	COG4133	protoheme IX ABC transporter activity
A0U92_RS09935	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A0U92_RS09940	COG1253	flavin adenine dinucleotide binding
A0U92_RS09945	COG0535	radical SAM domain protein
A0U92_RS09950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A0U92_RS09970	COG3394	polysaccharide catabolic process
A0U92_RS09980	COG2945	thiolester hydrolase activity
A0U92_RS09985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A0U92_RS10000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A0U92_RS10005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A0U92_RS10010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A0U92_RS10025	COG0024	Methionine aminopeptidase
A0U92_RS10040	COG0137	argininosuccinate synthase activity
A0U92_RS10045	COG0545	Peptidyl-prolyl cis-trans isomerase
A0U92_RS10060	COG0180	Tryptophanyl-tRNA synthetase
A0U92_RS10065	COG1058	Belongs to the CinA family
A0U92_RS10065	COG1546	Belongs to the CinA family
A0U92_RS10070	COG0668	transmembrane transport
A0U92_RS10075	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A0U92_RS10080	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A0U92_RS10115	COG0248	Ppx GppA phosphatase
A0U92_RS10140	COG0010	Belongs to the arginase family
A0U92_RS10155	COG1028	Short-chain dehydrogenase reductase Sdr
A0U92_RS10170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0U92_RS10180	COG0505	Belongs to the CarA family
A0U92_RS10190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A0U92_RS10195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A0U92_RS10200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A0U92_RS10210	COG0799	negative regulation of ribosome biogenesis
A0U92_RS10215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A0U92_RS10220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A0U92_RS10225	COG0012	GTP binding
A0U92_RS10230	COG0193	aminoacyl-tRNA hydrolase activity
A0U92_RS10235	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A0U92_RS10265	COG0768	penicillin binding
A0U92_RS10270	COG0772	Belongs to the SEDS family
A0U92_RS10285	COG0484	heat shock protein binding
A0U92_RS10290	COG0025	NhaP-type Na H and K H
A0U92_RS10300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A0U92_RS10305	COG0277	FAD linked oxidase domain protein
A0U92_RS10310	COG2244	polysaccharide biosynthetic process
A0U92_RS10315	COG0481	GTPase activity
A0U92_RS10325	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A0U92_RS10340	COG0431	NADPH-dependent FMN reductase
A0U92_RS10355	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A0U92_RS10360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A0U92_RS10365	COG0552	protein localization to endoplasmic reticulum
A0U92_RS10385	COG1749	Flagellar hook protein flgE
A0U92_RS10425	COG0667	Aldo Keto reductase
A0U92_RS10440	COG1054	Belongs to the UPF0176 family
A0U92_RS10470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A0U92_RS10475	COG3158	transport of potassium into the cell
A0U92_RS10480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A0U92_RS10495	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A0U92_RS10500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A0U92_RS10505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A0U92_RS10510	COG0424	maF-like protein
A0U92_RS10520	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
A0U92_RS10600	COG0315	cyclic pyranopterin monophosphate synthase activity
A0U92_RS10615	COG0723	plastoquinol--plastocyanin reductase activity
A0U92_RS10620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A0U92_RS10630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A0U92_RS10655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A0U92_RS10670	COG0113	porphobilinogen synthase activity
A0U92_RS10680	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
A0U92_RS10690	COG2205	protein histidine kinase activity
A0U92_RS10710	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
A0U92_RS10740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A0U92_RS10760	COG0514	ATP-dependent DNA helicase (RecQ)
A0U92_RS10770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A0U92_RS10775	COG4988	ABC transporter
A0U92_RS10800	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A0U92_RS10805	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A0U92_RS10825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A0U92_RS10830	COG3750	Belongs to the UPF0335 family
A0U92_RS10835	COG2072	flavoprotein involved in K transport
A0U92_RS10855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A0U92_RS10870	COG2351	hydroxyisourate hydrolase activity
A0U92_RS10880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A0U92_RS10885	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A0U92_RS10890	COG2244	polysaccharide biosynthetic process
A0U92_RS10900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0U92_RS10900	COG1372	Participates in initiation and elongation during chromosome replication
A0U92_RS10905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0U92_RS10905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A0U92_RS10915	COG1079	Belongs to the binding-protein-dependent transport system permease family
A0U92_RS10925	COG3845	ABC transporter
A0U92_RS10930	COG1744	ABC transporter substrate-binding protein PnrA-like
A0U92_RS10935	COG1335	isochorismatase
A0U92_RS10940	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A0U92_RS10990	COG2814	Major facilitator Superfamily
A0U92_RS11010	COG1596	polysaccharide export
A0U92_RS11040	COG1032	radical SAM domain protein
A0U92_RS11050	COG2835	tetraacyldisaccharide 4'-kinase activity
A0U92_RS11055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A0U92_RS11065	COG1028	Short-chain dehydrogenase reductase Sdr
A0U92_RS11070	COG2207	Transcriptional regulator
A0U92_RS11090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A0U92_RS11105	COG3956	TIGRFAM MazG family protein
A0U92_RS11120	COG1116	anion transmembrane transporter activity
A0U92_RS11125	COG1136	(ABC) transporter
A0U92_RS11135	COG0442	prolyl-tRNA aminoacylation
A0U92_RS11150	COG0493	'glutamate synthase
A0U92_RS11170	COG1953	Uracil, thiamine, allantoin
A0U92_RS11185	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A0U92_RS11195	COG1007	ATP synthesis coupled electron transport
A0U92_RS11215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0U92_RS11220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A0U92_RS11225	COG1034	ATP synthesis coupled electron transport
A0U92_RS11235	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
A0U92_RS11240	COG0649	NAD binding
A0U92_RS11245	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0U92_RS11250	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0U92_RS11255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0U92_RS11265	COG0776	regulation of translation
A0U92_RS11275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A0U92_RS11280	COG0740	serine-type endopeptidase activity
A0U92_RS11285	COG0544	peptidyl-prolyl cis-trans isomerase activity
A0U92_RS11295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A0U92_RS11295	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A0U92_RS11305	COG0513	Belongs to the DEAD box helicase family
A0U92_RS11310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A0U92_RS11330	COG2814	Major facilitator Superfamily
A0U92_RS11355	COG3300	MHYT domain
A0U92_RS11355	COG5001	Diguanylate cyclase
A0U92_RS11360	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
A0U92_RS11380	COG2837	iron assimilation
A0U92_RS11390	COG0436	Aminotransferase
A0U92_RS11395	COG0347	Belongs to the P(II) protein family
A0U92_RS11410	COG0405	Gamma-glutamyltransferase
A0U92_RS11420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A0U92_RS11425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A0U92_RS11430	COG0328	RNA-DNA hybrid ribonuclease activity
A0U92_RS11450	COG0538	isocitrate dehydrogenase activity
A0U92_RS11500	COG1126	abc transporter atp-binding protein
A0U92_RS11505	COG0583	DNA-binding transcription factor activity
A0U92_RS11515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A0U92_RS11525	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A0U92_RS11535	COG2072	flavoprotein involved in K transport
A0U92_RS11555	COG3665	Urea carboxylase-associated protein
A0U92_RS11565	COG0864	Transcriptional regulator
A0U92_RS11570	COG1116	anion transmembrane transporter activity
A0U92_RS11575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0U92_RS11580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0U92_RS11600	COG0438	transferase activity, transferring glycosyl groups
A0U92_RS11605	COG1215	transferase activity, transferring glycosyl groups
A0U92_RS11615	COG2003	Belongs to the UPF0758 family
A0U92_RS11620	COG2814	Major facilitator Superfamily
A0U92_RS11625	COG1566	PFAM secretion protein HlyD family protein
A0U92_RS11645	COG1684	flagellar biosynthetic protein fliR
A0U92_RS11650	COG1987	bacterial-type flagellum assembly
A0U92_RS11655	COG1677	Flagellar hook-basal body complex protein FliE
A0U92_RS11660	COG1558	bacterial-type flagellum-dependent cell motility
A0U92_RS11665	COG1815	bacterial-type flagellum-dependent cell motility
A0U92_RS11675	COG1338	Plays a role in the flagellum-specific transport system
A0U92_RS11680	COG3265	gluconokinase activity
A0U92_RS11685	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A0U92_RS11690	COG0363	glucosamine-6-phosphate deaminase activity
A0U92_RS11695	COG0561	phosphatase activity
A0U92_RS11700	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A0U92_RS11705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A0U92_RS11720	COG1570	exodeoxyribonuclease VII activity
A0U92_RS11730	COG0179	Fumarylacetoacetate (FAA) hydrolase
A0U92_RS11735	COG0438	transferase activity, transferring glycosyl groups
A0U92_RS11735	COG1216	Glycosyl transferase, family 2
A0U92_RS11745	COG1657	PFAM Prenyltransferase squalene oxidase
A0U92_RS11750	COG1233	COG1233 Phytoene dehydrogenase and related
A0U92_RS11755	COG1562	ergosterol biosynthetic process
A0U92_RS11760	COG1562	ergosterol biosynthetic process
A0U92_RS11775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0U92_RS11785	COG0287	Prephenate dehydrogenase
A0U92_RS11800	COG0582	viral genome integration into host DNA
A0U92_RS11880	COG0109	protoheme IX farnesyltransferase activity
A0U92_RS11890	COG2226	methyltransferase
A0U92_RS11905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A0U92_RS11910	COG1360	Flagellar Motor Protein
A0U92_RS11925	COG1522	sequence-specific DNA binding
A0U92_RS11930	COG0492	ferredoxin-NADP+ reductase activity
A0U92_RS11935	COG0583	DNA-binding transcription factor activity
A0U92_RS11940	COG1321	iron dependent repressor
A0U92_RS11955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A0U92_RS11985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0U92_RS11990	COG4957	zinc ion binding
A0U92_RS11995	COG0616	signal peptide processing
A0U92_RS12000	COG0776	regulation of translation
A0U92_RS12010	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
A0U92_RS12010	COG0662	Cupin 2, conserved barrel domain protein
A0U92_RS12030	COG0629	single-stranded DNA binding
A0U92_RS12040	COG1396	sequence-specific DNA binding
A0U92_RS12045	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A0U92_RS12075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A0U92_RS12095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A0U92_RS12115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A0U92_RS12130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A0U92_RS12150	COG0670	Belongs to the BI1 family
A0U92_RS12170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A0U92_RS12175	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A0U92_RS12180	COG0706	membrane insertase activity
A0U92_RS12190	COG0594	ribonuclease P activity
A0U92_RS12195	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A0U92_RS12205	COG0346	lactoylglutathione lyase activity
A0U92_RS12210	COG3594	Acyltransferase
A0U92_RS12215	COG3494	Protein of unknown function (DUF1009)
A0U92_RS12220	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A0U92_RS12225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A0U92_RS12230	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A0U92_RS12240	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A0U92_RS12245	COG0750	zinc metalloprotease
A0U92_RS12250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A0U92_RS12255	COG0575	Belongs to the CDS family
A0U92_RS12260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A0U92_RS12265	COG0233	cytoplasmic translational termination
A0U92_RS12270	COG0528	UMP kinase activity
A0U92_RS12275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A0U92_RS12280	COG0571	ribonuclease III activity
A0U92_RS12285	COG0681	Belongs to the peptidase S26 family
A0U92_RS12290	COG0736	holo-[acyl-carrier-protein] synthase activity
A0U92_RS12295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A0U92_RS12300	COG1758	RNA polymerase activity
A0U92_RS12330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A0U92_RS12340	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
A0U92_RS12365	COG2096	Adenosyltransferase
A0U92_RS12385	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A0U92_RS12420	COG0776	regulation of translation
A0U92_RS12425	COG3754	Rhamnan synthesis protein F
A0U92_RS12450	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A0U92_RS12455	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A0U92_RS12460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A0U92_RS12465	COG0509	glycine decarboxylation via glycine cleavage system
A0U92_RS12470	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A0U92_RS12470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A0U92_RS12485	COG1012	belongs to the aldehyde dehydrogenase family
A0U92_RS12490	COG1252	NADH dehydrogenase
A0U92_RS12540	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A0U92_RS12545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A0U92_RS12580	COG3609	addiction module antidote protein, CC2985 family
A0U92_RS12605	COG2801	Transposase and inactivated derivatives
A0U92_RS12640	COG4774	siderophore transport
A0U92_RS12645	COG4974	Belongs to the 'phage' integrase family
A0U92_RS12690	COG2207	Transcriptional regulator
A0U92_RS12705	COG0464	growth
A0U92_RS12715	COG3451	type IV secretory pathway VirB4
A0U92_RS12720	COG3451	type IV secretory pathway VirB4
A0U92_RS12735	COG3451	type IV secretory pathway VirB4
A0U92_RS12750	COG4962	Type ii secretion system protein e
A0U92_RS12795	COG1335	isochorismatase
A0U92_RS12805	COG0741	lytic transglycosylase activity
A0U92_RS12815	COG4959	Type IV secretory pathway protease TraF
A0U92_RS12845	COG1794	racemase activity, acting on amino acids and derivatives
A0U92_RS12890	COG4974	Belongs to the 'phage' integrase family
A0U92_RS12920	COG0741	lytic transglycosylase activity
A0U92_RS12920	COG1196	nuclear chromosome segregation
A0U92_RS12920	COG0739	heme binding
A0U92_RS12960	COG0784	Response regulator, receiver
A0U92_RS12965	COG0488	(ABC) transporter
A0U92_RS12975	COG0326	Molecular chaperone. Has ATPase activity
A0U92_RS13050	COG2010	Cytochrome c
A0U92_RS13050	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A0U92_RS13055	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A0U92_RS13060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A0U92_RS13070	COG1607	acyl-coa hydrolase
A0U92_RS13075	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A0U92_RS13080	COG0354	folic acid binding
A0U92_RS13085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A0U92_RS13090	COG0242	peptide deformylase activity
A0U92_RS13100	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A0U92_RS13105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A0U92_RS13115	COG1722	exodeoxyribonuclease VII activity
A0U92_RS13125	COG1940	carbohydrate kinase activity
A0U92_RS13130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A0U92_RS13160	COG2321	neutral zinc metallopeptidase
A0U92_RS13170	COG0542	response to heat
A0U92_RS13185	COG5487	UPF0391 membrane protein
A0U92_RS13195	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
A0U92_RS13200	COG1877	trehalose-phosphatase activity
A0U92_RS13225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0U92_RS13235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0U92_RS13255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A0U92_RS13260	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A0U92_RS13270	COG5265	(ABC) transporter
A0U92_RS13285	COG0156	8-amino-7-oxononanoate synthase activity
A0U92_RS13295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A0U92_RS13295	COG4106	trans-aconitate 2-methyltransferase activity
A0U92_RS13300	COG0513	Belongs to the DEAD box helicase family
A0U92_RS13305	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A0U92_RS13310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A0U92_RS13315	COG3572	ergothioneine biosynthetic process
A0U92_RS13320	COG0737	Belongs to the 5'-nucleotidase family
A0U92_RS13325	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A0U92_RS13325	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A0U92_RS13330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A0U92_RS13335	COG0314	molybdopterin synthase activity
A0U92_RS13340	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A0U92_RS13350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A0U92_RS13355	COG0322	excinuclease ABC activity
A0U92_RS13385	COG0745	RESPONSE REGULATOR receiver
A0U92_RS13410	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A0U92_RS13415	COG1216	Glycosyl transferase, family 2
A0U92_RS13415	COG0438	transferase activity, transferring glycosyl groups
A0U92_RS13430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A0U92_RS13450	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A0U92_RS13455	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A0U92_RS13460	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A0U92_RS13465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A0U92_RS13470	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A0U92_RS13475	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A0U92_RS13480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A0U92_RS13485	COG0477	Major facilitator Superfamily
A0U92_RS13500	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A0U92_RS13515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A0U92_RS13525	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A0U92_RS13530	COG1053	succinate dehydrogenase
A0U92_RS13535	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A0U92_RS13550	COG2824	Alkylphosphonate utilization operon protein PhnA
A0U92_RS13570	COG0488	(ABC) transporter
A0U92_RS13585	COG0628	permease
A0U92_RS13605	COG0415	Belongs to the DNA photolyase family
A0U92_RS13635	COG1566	PFAM secretion protein HlyD family protein
A0U92_RS13680	COG0586	Pfam SNARE associated Golgi protein
A0U92_RS13685	COG1028	Short-chain dehydrogenase reductase Sdr
A0U92_RS13690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0U92_RS13700	COG0140	phosphoribosyl-ATP diphosphatase activity
A0U92_RS13705	COG0107	imidazoleglycerol-phosphate synthase activity
A0U92_RS13710	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A0U92_RS13715	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A0U92_RS13725	COG0131	Imidazoleglycerol-phosphate dehydratase
A0U92_RS13730	COG3300	MHYT domain
A0U92_RS13730	COG5001	Diguanylate cyclase
A0U92_RS13755	COG0438	transferase activity, transferring glycosyl groups
A0U92_RS13765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A0U92_RS13780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0U92_RS13800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A0U92_RS13805	COG0531	amino acid
A0U92_RS13810	COG1253	flavin adenine dinucleotide binding
A0U92_RS13830	COG2801	Transposase and inactivated derivatives
A0U92_RS13885	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A0U92_RS13890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0U92_RS13890	COG0072	phenylalanine-tRNA ligase activity
A0U92_RS13895	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
A0U92_RS13900	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A0U92_RS13940	COG0473	3-isopropylmalate dehydrogenase activity
A0U92_RS13970	COG1012	belongs to the aldehyde dehydrogenase family
A0U92_RS13990	COG1414	Transcriptional regulator
A0U92_RS14000	COG0477	Major facilitator Superfamily
A0U92_RS14015	COG2267	carboxylic ester hydrolase activity
A0U92_RS14040	COG2723	6-phospho-beta-galactosidase activity
A0U92_RS14100	COG3511	phospholipase C
A0U92_RS14105	COG3511	phospholipase C
A0U92_RS14130	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
A0U92_RS14150	COG2333	competence protein COMEC
A0U92_RS14150	COG0658	competence protein
A0U92_RS14170	COG0483	inositol monophosphate 1-phosphatase activity
A0U92_RS14175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A0U92_RS14190	COG0776	regulation of translation
A0U92_RS14195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A0U92_RS14200	COG0416	fatty acid biosynthetic process
A0U92_RS14205	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A0U92_RS14225	COG0745	RESPONSE REGULATOR receiver
A0U92_RS14240	COG0242	peptide deformylase activity
A0U92_RS14245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A0U92_RS14295	COG0646	methionine synthase
A0U92_RS14295	COG1410	methionine synthase
A0U92_RS14300	COG2132	Multicopper oxidase
A0U92_RS14310	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A0U92_RS14315	COG0492	ferredoxin-NADP+ reductase activity
A0U92_RS14320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0U92_RS14325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A0U92_RS14345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A0U92_RS14360	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A0U92_RS14365	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A0U92_RS14375	COG0598	Magnesium transport protein CorA
A0U92_RS14385	COG1091	dTDP-4-dehydrorhamnose reductase activity
A0U92_RS14395	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A0U92_RS14430	COG0583	DNA-binding transcription factor activity
A0U92_RS14465	COG3451	type IV secretory pathway VirB4
A0U92_RS14490	COG5489	Protein of unknown function (DUF736)
A0U92_RS14545	COG4974	Belongs to the 'phage' integrase family
A0U92_RS14550	COG0517	IMP dehydrogenase activity
A0U92_RS14555	COG0789	Transcriptional regulator
A0U92_RS14630	COG2132	Multicopper oxidase
A0U92_RS14640	COG1937	Protein conserved in bacteria
A0U92_RS14655	COG3436	PFAM IS66 Orf2 family protein
A0U92_RS14660	COG4372	Transposase
A0U92_RS14675	COG4974	Belongs to the 'phage' integrase family
A0U92_RS14690	COG0523	cobalamin synthesis protein
A0U92_RS14705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A0U92_RS14755	COG2271	Major facilitator Superfamily
A0U92_RS14765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A0U92_RS14810	COG0583	DNA-binding transcription factor activity
A0U92_RS14835	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A0U92_RS14840	COG1984	allophanate hydrolase subunit 2
A0U92_RS14845	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A0U92_RS14885	COG2814	Major facilitator Superfamily
A0U92_RS14910	COG4974	Belongs to the 'phage' integrase family
A0U92_RS14915	COG4774	siderophore transport
A0U92_RS14945	COG0848	biopolymer transport protein
A0U92_RS14975	COG4774	siderophore transport
A0U92_RS15025	COG3838	Conjugal transfer protein Trbc
A0U92_RS15045	COG5489	Protein of unknown function (DUF736)
A0U92_RS15070	COG4774	siderophore transport
A0U92_RS15090	COG1595	DNA-templated transcription, initiation
A0U92_RS15095	COG0745	RESPONSE REGULATOR receiver
A0U92_RS15100	COG2205	protein histidine kinase activity
A0U92_RS15105	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
A0U92_RS15110	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A0U92_RS15115	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A0U92_RS15130	COG3158	transport of potassium into the cell
A0U92_RS15220	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A0U92_RS15225	COG0343	queuine tRNA-ribosyltransferase activity
A0U92_RS15245	COG4774	siderophore transport
A0U92_RS15260	COG0778	Nitroreductase
A0U92_RS15265	COG5564	TIM-barrel signal transduction protein
A0U92_RS15270	COG5441	Belongs to the UPF0261 family
A0U92_RS15285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0U92_RS15300	COG0179	Fumarylacetoacetate (FAA) hydrolase
A0U92_RS15330	COG1024	Enoyl-CoA hydratase
A0U92_RS15335	COG0028	Belongs to the TPP enzyme family
A0U92_RS15360	COG0464	growth
A0U92_RS15380	COG1335	isochorismatase
A0U92_RS15395	COG0625	glutathione transferase activity
A0U92_RS15405	COG1595	DNA-templated transcription, initiation
A0U92_RS15410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0U92_RS15415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0U92_RS15420	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
A0U92_RS15425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A0U92_RS15465	COG0235	Class ii aldolase
A0U92_RS15490	COG0765	amino acid transport
A0U92_RS15505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0U92_RS15620	COG0400	carboxylic ester hydrolase activity
A0U92_RS15625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A0U92_RS15630	COG0640	Transcriptional regulator
A0U92_RS15705	COG4974	Belongs to the 'phage' integrase family
A0U92_RS15770	COG0656	L-ascorbic acid biosynthetic process
A0U92_RS15780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A0U92_RS15790	COG2814	Major facilitator Superfamily
A0U92_RS15800	COG0009	L-threonylcarbamoyladenylate synthase
A0U92_RS15815	COG1280	lysine exporter protein (LysE YggA)
A0U92_RS15820	COG4774	siderophore transport
A0U92_RS15830	COG0305	Participates in initiation and elongation during chromosome replication
A0U92_RS15835	COG4716	Myosin-crossreactive antigen
A0U92_RS15855	COG1294	oxidase, subunit
A0U92_RS15860	COG1271	oxidase subunit
A0U92_RS15865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A0U92_RS15870	COG4988	ABC transporter
A0U92_RS15880	COG0450	alkyl hydroperoxide reductase
A0U92_RS15900	COG0583	DNA-binding transcription factor activity
A0U92_RS15915	COG0625	glutathione transferase activity
A0U92_RS15950	COG0235	Class ii aldolase
A0U92_RS15970	COG0154	amidase activity
A0U92_RS15975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0U92_RS15995	COG4638	Rieske (2fe-2S)
A0U92_RS16000	COG1960	acyl-CoA dehydrogenase activity
A0U92_RS16005	COG1012	belongs to the aldehyde dehydrogenase family
A0U92_RS16030	COG2217	Heavy metal translocating P-type atpase
A0U92_RS16050	COG3128	pkhd-type hydroxylase
A0U92_RS16075	COG0135	phosphoribosylanthranilate isomerase activity
A0U92_RS16080	COG0284	orotidine-5'-phosphate decarboxylase activity
A0U92_RS16110	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A0U92_RS16115	COG0602	queuosine metabolic process
A0U92_RS16120	COG1742	UPF0060 membrane protein
A0U92_RS16135	COG1959	2 iron, 2 sulfur cluster binding
A0U92_RS16145	COG1121	(ABC) transporter
A0U92_RS16150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A0U92_RS16160	COG3128	pkhd-type hydroxylase
A0U92_RS16180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0U92_RS16200	COG0859	PFAM glycosyl transferase family 9
A0U92_RS16205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A0U92_RS16210	COG1959	2 iron, 2 sulfur cluster binding
A0U92_RS16220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0U92_RS16225	COG1120	ATPase activity
A0U92_RS16240	COG0456	acetyltransferase
A0U92_RS16245	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A0U92_RS16255	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A0U92_RS16260	COG1104	cysteine desulfurase activity
A0U92_RS16270	COG0482	sulfurtransferase activity
A0U92_RS16290	COG1505	serine-type exopeptidase activity
A0U92_RS16330	COG0424	maF-like protein
A0U92_RS16335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A0U92_RS16340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A0U92_RS16345	COG1981	membrane
A0U92_RS16390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A0U92_RS16395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A0U92_RS16405	COG1129	ABC transporter
A0U92_RS16425	COG0784	Response regulator, receiver
A0U92_RS16425	COG5002	protein histidine kinase activity
A0U92_RS16425	COG2198	Histidine kinase
A0U92_RS16435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0U92_RS16440	COG1914	H( )-stimulated, divalent metal cation uptake system
A0U92_RS16445	COG0436	Aminotransferase
A0U92_RS16460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A0U92_RS16510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A0U92_RS16550	COG0357	Ribosomal RNA small subunit methyltransferase G
A0U92_RS16555	COG0445	tRNA wobble uridine modification
A0U92_RS16560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A0U92_RS16565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A0U92_RS16590	COG4232	protein-disulfide reductase activity
A0U92_RS16595	COG1643	Atp-dependent helicase
A0U92_RS16605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A0U92_RS16610	COG0642	Histidine kinase
A0U92_RS16615	COG0745	RESPONSE REGULATOR receiver
A0U92_RS16620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A0U92_RS16625	COG0443	Heat shock 70 kDa protein
A0U92_RS16630	COG0484	heat shock protein binding
A0U92_RS16650	COG1294	oxidase, subunit
A0U92_RS16655	COG1271	oxidase subunit
A0U92_RS16680	COG1278	Cold shock
A0U92_RS16690	COG1881	PFAM PEBP family protein
A0U92_RS16725	COG0318	PFAM AMP-dependent synthetase and ligase
A0U92_RS16735	COG0156	8-amino-7-oxononanoate synthase activity
A0U92_RS16740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0U92_RS16780	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A0U92_RS16815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0U92_RS16835	COG0246	Mannitol dehydrogenase
A0U92_RS16840	COG1136	(ABC) transporter
A0U92_RS16855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A0U92_RS16855	COG0519	Catalyzes the synthesis of GMP from XMP
A0U92_RS16860	COG1695	Transcriptional regulator
A0U92_RS16880	COG0402	S-adenosylhomocysteine deaminase activity
A0U92_RS16915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A0U92_RS16920	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
A0U92_RS16925	COG1138	Cytochrome C-type biogenesis protein
A0U92_RS16930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A0U92_RS16935	COG3088	subunit of a heme lyase
A0U92_RS16945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A0U92_RS16950	COG2813	Specifically methylates the guanine in position
A0U92_RS16950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A0U92_RS16960	COG0513	Belongs to the DEAD box helicase family
A0U92_RS16965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A0U92_RS16975	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A0U92_RS16990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A0U92_RS16995	COG0408	coproporphyrinogen oxidase activity
A0U92_RS17010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A0U92_RS17020	COG1660	Displays ATPase and GTPase activities
A0U92_RS17050	COG0297	glycogen (starch) synthase activity
A0U92_RS17060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes