locus-tag	class	description
FCN51_RS00005	ENOG4108UUM	single-stranded DNA-binding protein
FCN51_RS00060	ENOG4107QHF	type ii secretion system protein e
FCN51_RS00100	ENOG4105CZX	twitching motility protein
FCN51_RS00170	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FCN51_RS00255	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
FCN51_RS00265	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
FCN51_RS00320	ENOG4105C7H	Helicase, RecD TraA family
FCN51_RS00445	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FCN51_RS00470	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FCN51_RS00540	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FCN51_RS00545	ENOG4105C0B	DNA polymerase III (alpha subunit)
FCN51_RS00550	ENOG4105C4R	Atp-dependent dna helicase
FCN51_RS00645	ENOG4105K70	DNA-binding protein
FCN51_RS00655	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FCN51_RS00720	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCN51_RS00740	ENOG4107RZZ	dna polymerase iii epsilon subunit
FCN51_RS00755	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
FCN51_RS00820	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FCN51_RS00865	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FCN51_RS00890	ENOG4105Y2X	UPF0335 protein
FCN51_RS00895	ENOG4105UT3	Methyl-accepting chemotaxis
FCN51_RS00900	ENOG4105BZE	flagellar hook protein, FlgE
FCN51_RS00905	ENOG4105D00	flagellar biosynthetic protein flhB
FCN51_RS00915	ENOG4105VS8	Flagellar biosynthetic protein fliq
FCN51_RS00935	ENOG4105SFI	flagellar basal-body rod protein
FCN51_RS00940	ENOG4108ZC9	flagellar basal-body rod protein flgc
FCN51_RS00945	ENOG4107W75	Flagellin
FCN51_RS00975	ENOG4105KTQ	flagellar basal-body rod protein
FCN51_RS00980	ENOG4105CGA	flagellar basal-body rod protein FlgG
FCN51_RS00990	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FCN51_RS01005	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FCN51_RS01010	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FCN51_RS01020	ENOG4105DD5	Flagellar motor switch protein
FCN51_RS01030	ENOG4105CN7	Flagellar biosynthetic protein FliP
FCN51_RS01040	ENOG4105D7B	Flagellar biosynthesis protein flha
FCN51_RS01055	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FCN51_RS01060	ENOG41065XG	Chemotactic signal-response protein CheL
FCN51_RS01085	ENOG4108JIR	Flagellum-specific ATP synthase
FCN51_RS01100	ENOG4105ER2	Ompa motb domain protein
FCN51_RS01105	ENOG4107RD7	Flagellar Motor Protein, MotA
FCN51_RS01115	ENOG4105W00	Flagellar hook capping protein
FCN51_RS01235	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
FCN51_RS01420	ENOG4105ENG	CRISPR-associated protein, Csy1 family
FCN51_RS01455	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FCN51_RS01575	ENOG41060M0	Crispr-associated protein, cse4 family
FCN51_RS01595	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FCN51_RS01650	ENOG4105UT3	Methyl-accepting chemotaxis
FCN51_RS01675	ENOG4105CG5	Glycosyl transferase (Group 1
FCN51_RS01700	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCN51_RS01710	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FCN51_RS01725	ENOG4105CEC	DNA methylase N-4 N-6
FCN51_RS01740	ENOG4105M6W	Crispr-associated protein, Csy3 family
FCN51_RS01765	ENOG4105ENG	CRISPR-associated protein, Csy1 family
FCN51_RS01885	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FCN51_RS01890	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FCN51_RS01920	ENOG4107QXV	Phosphate transporter
FCN51_RS01970	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
FCN51_RS01980	ENOG4105D7V	transposase
FCN51_RS02035	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
FCN51_RS02040	ENOG4108VYJ	response regulator receiver protein
FCN51_RS02045	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FCN51_RS02050	ENOG4105BZU	Histidine kinase
FCN51_RS02055	ENOG4108V3W	Chemotaxis protein, CheW
FCN51_RS02060	ENOG4105CBS	Chea signal transduction histidine kinase
FCN51_RS02065	ENOG4108VYJ	response regulator receiver protein
FCN51_RS02075	ENOG4105C8Q	Methyl-accepting chemotaxis
FCN51_RS02105	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCN51_RS02110	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FCN51_RS02115	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FCN51_RS02120	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FCN51_RS02125	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FCN51_RS02130	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FCN51_RS02135	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FCN51_RS02145	ENOG4105CP7	Triose-phosphate isomerase
FCN51_RS02155	ENOG4105CRQ	synthase (Component I)
FCN51_RS02160	ENOG4105DDQ	anthranilate synthase
FCN51_RS02165	ENOG4107QYG	anthranilate phosphoribosyltransferase
FCN51_RS02170	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FCN51_RS02175	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCN51_RS02180	ENOG4108JYK	Dehydrogenase
FCN51_RS02185	ENOG4105CPP	Dehydrogenase, E1 component
FCN51_RS02190	ENOG4105C7S	Dehydrogenase
FCN51_RS02195	ENOG4107QN2	dihydrolipoyl dehydrogenase
FCN51_RS02200	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FCN51_RS02215	ENOG4107TH8	cina domain protein
FCN51_RS02225	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
FCN51_RS02230	ENOG4108ZCF	integral membrane protein
FCN51_RS02235	ENOG4105C83	adenylosuccinate lyase
FCN51_RS02240	ENOG4107QPR	SAICAR synthetase
FCN51_RS02245	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
FCN51_RS02255	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
FCN51_RS02260	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
FCN51_RS02285	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FCN51_RS02295	ENOG4105IPI	Membrane
FCN51_RS02300	ENOG4105KHC	sulfurtransferase
FCN51_RS02305	ENOG4105C28	cystathionine
FCN51_RS02310	ENOG4105C0P	Mg chelatase subunit ChlI
FCN51_RS02315	ENOG4108JQ1	Dehydrogenase
FCN51_RS02325	ENOG4105XUA	cytochrome c
FCN51_RS02330	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FCN51_RS02335	ENOG4105CQC	Prephenate dehydratase
FCN51_RS02340	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FCN51_RS02345	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FCN51_RS02350	ENOG4105VEQ	Cold shock protein
FCN51_RS02385	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FCN51_RS02395	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FCN51_RS02400	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FCN51_RS02405	ENOG4105HHA	aminodeoxychorismate lyase
FCN51_RS02425	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FCN51_RS02430	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FCN51_RS02440	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
FCN51_RS02455	ENOG4105C11	sulfate adenylyltransferase), subunit 2
FCN51_RS02460	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
FCN51_RS02470	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FCN51_RS02475	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FCN51_RS02480	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
FCN51_RS02490	ENOG4105DWT	malate dehydrogenase (quinone)
FCN51_RS02495	ENOG4108Z9K	Osmotically inducible protein
FCN51_RS02500	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FCN51_RS02505	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
FCN51_RS02510	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
FCN51_RS02540	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FCN51_RS02545	ENOG4105DZ1	carboxypeptidase
FCN51_RS02550	ENOG4105K6T	rare lipoprotein A
FCN51_RS02555	ENOG4105CVE	Lytic murein transglycosylase
FCN51_RS02570	ENOG4105CUB	amino acid
FCN51_RS02575	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FCN51_RS02595	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FCN51_RS02605	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FCN51_RS02610	ENOG4105CUT	histidyl-tRNA synthetase
FCN51_RS02615	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FCN51_RS02625	ENOG4105EA8	2-Nitropropane dioxygenase
FCN51_RS02630	ENOG4105CFH	Aspartokinase
FCN51_RS02635	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FCN51_RS02640	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
FCN51_RS02655	ENOG4105VW4	glutaredoxin 3
FCN51_RS02660	ENOG4105MJ2	Competence protein
FCN51_RS02665	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FCN51_RS02670	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCN51_RS02690	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FCN51_RS02700	ENOG4105M85	Bola protein
FCN51_RS02705	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FCN51_RS02720	ENOG4105DY8	decarboxylase
FCN51_RS02725	ENOG4105DHU	Bile acid
FCN51_RS02740	ENOG4107NKQ	Flavinator of succinate dehydrogenase
FCN51_RS02745	ENOG4105CB5	ATP-dependent DNA helicase recG
FCN51_RS02755	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FCN51_RS02775	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FCN51_RS02785	ENOG4105W0E	50S ribosomal protein L33
FCN51_RS02790	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FCN51_RS02795	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FCN51_RS02800	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
FCN51_RS02810	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FCN51_RS02815	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FCN51_RS02820	ENOG4108ZAF	Molybdopterin
FCN51_RS02825	ENOG4105M00	molybdopterin converting factor, subunit 1
FCN51_RS02840	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FCN51_RS02845	ENOG4108IGT	Dipeptidase
FCN51_RS02860	ENOG4105CFU	surface antigen
FCN51_RS02870	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCN51_RS02880	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FCN51_RS02885	ENOG4105C37	(CBS) domain
FCN51_RS02890	ENOG4108R9S	DSBA oxidoreductase
FCN51_RS02915	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
FCN51_RS02920	ENOG4105M4E	phosphohistidine phosphatase, SixA
FCN51_RS02935	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FCN51_RS02940	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FCN51_RS02945	ENOG4105EAH	synthase
FCN51_RS02955	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FCN51_RS02960	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FCN51_RS02970	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FCN51_RS02975	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FCN51_RS02985	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FCN51_RS02990	ENOG41082FS	50S ribosomal protein L31
FCN51_RS02995	ENOG4108ZNX	Heat shock protein
FCN51_RS03015	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FCN51_RS03020	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FCN51_RS03025	ENOG4105W5Q	DNA repair protein (RadC
FCN51_RS03030	ENOG4105W5Q	DNA repair protein (RadC
FCN51_RS03040	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
FCN51_RS03045	ENOG4105DC7	peptidase M24
FCN51_RS03050	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FCN51_RS03060	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FCN51_RS03065	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FCN51_RS03100	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FCN51_RS03105	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FCN51_RS03110	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FCN51_RS03115	ENOG41082BR	50S ribosomal protein L35
FCN51_RS03120	ENOG4105DEI	Mannitol dehydrogenase
FCN51_RS03125	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
FCN51_RS03140	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
FCN51_RS03145	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FCN51_RS03150	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FCN51_RS03175	ENOG4105CAK	Cell division ATP-binding protein ftsE
FCN51_RS03190	ENOG4105C4W	S-formylglutathione hydrolase
FCN51_RS03195	ENOG4105FFC	UPF0187 protein
FCN51_RS03200	ENOG4108VJ1	Transcriptional regulator (CarD family
FCN51_RS03205	ENOG4105RQ9	TPR repeat-containing protein
FCN51_RS03215	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FCN51_RS03220	ENOG4105CBX	hi0933 family
FCN51_RS03230	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
FCN51_RS03235	ENOG4107QMS	site-determining protein
FCN51_RS03240	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
FCN51_RS03245	ENOG4108WYP	Transcriptional regulator
FCN51_RS03250	ENOG4105BZ1	(ABC) transporter
FCN51_RS03270	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
FCN51_RS03275	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FCN51_RS03280	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FCN51_RS03285	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FCN51_RS03290	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FCN51_RS03295	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FCN51_RS03300	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FCN51_RS03310	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCN51_RS03315	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FCN51_RS03325	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FCN51_RS03330	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FCN51_RS03335	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FCN51_RS03340	ENOG4105C7B	Threonine dehydratase
FCN51_RS03345	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FCN51_RS03355	ENOG4105CN1	protease
FCN51_RS03365	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FCN51_RS03370	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FCN51_RS03380	ENOG4105BZ1	(ABC) transporter
FCN51_RS03385	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FCN51_RS03395	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FCN51_RS03420	ENOG4105CEC	DNA methylase N-4 N-6
FCN51_RS03425	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FCN51_RS03435	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FCN51_RS03440	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FCN51_RS03445	ENOG4105BZS	acriflavin resistance protein
FCN51_RS03455	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FCN51_RS03470	ENOG4105D7T	ABC transporter
FCN51_RS03475	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
FCN51_RS03485	ENOG4108ZT0	50S ribosomal protein l17
FCN51_RS03490	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FCN51_RS03495	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FCN51_RS03500	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FCN51_RS03505	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FCN51_RS03515	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FCN51_RS03520	ENOG41084HQ	50S ribosomal protein L30
FCN51_RS03525	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FCN51_RS03530	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FCN51_RS03535	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FCN51_RS03540	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FCN51_RS03545	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FCN51_RS03550	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FCN51_RS03555	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FCN51_RS03560	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FCN51_RS03565	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FCN51_RS03570	ENOG41083MP	50s ribosomal protein l29
FCN51_RS03575	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FCN51_RS03580	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FCN51_RS03585	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FCN51_RS03590	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FCN51_RS03595	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FCN51_RS03600	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FCN51_RS03605	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FCN51_RS03610	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FCN51_RS03615	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FCN51_RS03620	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FCN51_RS03625	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FCN51_RS03630	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FCN51_RS03635	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FCN51_RS03640	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FCN51_RS03645	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FCN51_RS03650	ENOG4108VZM	50s ribosomal protein L10
FCN51_RS03655	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FCN51_RS03660	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FCN51_RS03665	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FCN51_RS03695	ENOG4105CSH	Transporter
FCN51_RS03705	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FCN51_RS03735	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FCN51_RS03770	ENOG41060IM	Heme exporter protein
FCN51_RS03775	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
FCN51_RS03780	ENOG4105DA4	cytochrome c-type biogenesis protein
FCN51_RS03785	ENOG4107QX9	Thiol disulfide interChange protein
FCN51_RS03790	ENOG4105KWW	Biogenesis protein
FCN51_RS03815	ENOG4105DSW	Fusaric acid resistance protein
FCN51_RS03840	ENOG4105FDK	ABC transporter
FCN51_RS03860	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FCN51_RS03870	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FCN51_RS03875	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FCN51_RS03880	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FCN51_RS03885	ENOG4105DJV	ribulose-phosphate 3-epimerase
FCN51_RS03910	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FCN51_RS03915	ENOG4105E2X	shikimate dehydrogenase
FCN51_RS03935	ENOG4105CH7	arginosuccinase
FCN51_RS03950	ENOG4105CMR	udp-glucose 4-epimerase
FCN51_RS03955	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
FCN51_RS03965	ENOG4105YVS	arsR family transcriptional regulator
FCN51_RS03970	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FCN51_RS03975	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
FCN51_RS04015	ENOG4107RGH	Aldehyde dehydrogenase
FCN51_RS04025	ENOG4108RCM	Nitroreductase
FCN51_RS04045	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
FCN51_RS04050	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FCN51_RS04055	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FCN51_RS04060	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
FCN51_RS04075	ENOG4105CA0	peroxidase
FCN51_RS04080	ENOG4105CEC	DNA methylase N-4 N-6
FCN51_RS04090	ENOG4105GCF	PGAM
FCN51_RS04095	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FCN51_RS04105	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FCN51_RS04110	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FCN51_RS04115	ENOG4105D6S	protein involved in catabolism of external DNA
FCN51_RS04130	ENOG4105DK7	lysyl-tRNA synthetase
FCN51_RS04135	ENOG4105CEV	competence damage-inducible protein
FCN51_RS04140	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FCN51_RS04145	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCN51_RS04155	ENOG4105D49	3-dehydroquinate synthase
FCN51_RS04170	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FCN51_RS04175	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
FCN51_RS04180	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FCN51_RS04185	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
FCN51_RS04190	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCN51_RS04235	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FCN51_RS04250	ENOG4107QN2	dihydrolipoyl dehydrogenase
FCN51_RS04255	ENOG4105C7S	Dehydrogenase
FCN51_RS04265	ENOG4105D6Z	AFG1 family ATPase
FCN51_RS04275	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
FCN51_RS04280	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FCN51_RS04285	ENOG4105CXT	aspartate transcarbamylase
FCN51_RS04290	ENOG4105CD3	dihydroorotase
FCN51_RS04295	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FCN51_RS04300	ENOG4105C79	DNA protecting protein DprA
FCN51_RS04310	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FCN51_RS04315	ENOG4105CN1	protease
FCN51_RS04335	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FCN51_RS04350	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FCN51_RS04355	ENOG4107AQZ	Membrane
FCN51_RS04360	ENOG4105C8S	subunit m
FCN51_RS04365	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FCN51_RS04375	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FCN51_RS04380	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FCN51_RS04385	ENOG4105DTN	riboflavin biosynthesis protein ribF
FCN51_RS04390	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
FCN51_RS04395	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
FCN51_RS04400	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
FCN51_RS04420	ENOG4105C8Y	Acetylornithine aminotransferase
FCN51_RS04425	ENOG4105DBV	ornithine carbamoyltransferase
FCN51_RS04435	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FCN51_RS04445	ENOG4105CQ7	ATP-dependent helicase
FCN51_RS04455	ENOG4105CV8	reductase
FCN51_RS04465	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FCN51_RS04470	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
FCN51_RS04475	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FCN51_RS04500	ENOG4108WBT	adenosyltransferase
FCN51_RS04530	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCN51_RS04555	ENOG4105C85	amino acid
FCN51_RS04570	ENOG4107Y5K	Resolvase
FCN51_RS04600	ENOG4105CY3	ABC transporter, permease
FCN51_RS04605	ENOG4105DHJ	ABC, transporter
FCN51_RS04610	ENOG4105EGS	Mechanosensitive ion channel
FCN51_RS04625	ENOG4107SZR	mannose-6-phosphate isomerase
FCN51_RS04630	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FCN51_RS04635	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FCN51_RS04650	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FCN51_RS04660	ENOG4105C2X	Arabinose 5-phosphate isomerase
FCN51_RS04675	ENOG4108IUZ	ABC transporter
FCN51_RS04680	ENOG4105QVC	MOSC domain-containing protein
FCN51_RS04690	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
FCN51_RS04700	ENOG4108ZNX	Heat shock protein
FCN51_RS04715	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FCN51_RS04720	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FCN51_RS04730	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FCN51_RS04735	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
FCN51_RS04740	ENOG4105CAS	nag kinase
FCN51_RS04745	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FCN51_RS04750	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FCN51_RS04755	ENOG41087PG	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FCN51_RS04760	ENOG4105VG0	50S ribosomal protein l34
FCN51_RS04770	ENOG4108UYE	Lactoylglutathione lyase
FCN51_RS04775	ENOG4105GYT	Protein of unknown function (DUF1009)
FCN51_RS04780	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCN51_RS04785	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FCN51_RS04790	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCN51_RS04800	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FCN51_RS04805	ENOG4105DZP	Membrane-associated zinc metalloprotease
FCN51_RS04810	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FCN51_RS04820	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FCN51_RS04825	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FCN51_RS04830	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FCN51_RS04835	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FCN51_RS04840	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FCN51_RS04845	ENOG4105C3F	Signal peptidase i
FCN51_RS04850	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
FCN51_RS04855	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FCN51_RS04860	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FCN51_RS04865	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FCN51_RS04875	ENOG4107B2H	carbonic anhydrase
FCN51_RS04885	ENOG4105C1J	atp-dependent rna helicase
FCN51_RS04890	ENOG4105DWV	Homoserine O-trans-acetylase
FCN51_RS04895	ENOG4105DWV	Homoserine O-trans-acetylase
FCN51_RS04900	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FCN51_RS04915	ENOG4105DZG	Dehydrogenase
FCN51_RS04925	ENOG4105C5F	glutamine synthetase
FCN51_RS04930	ENOG4108YZA	Nitrogen regulatory protein pii
FCN51_RS04955	ENOG4105CAY	ferredoxin--nadp reductase
FCN51_RS04960	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FCN51_RS04970	ENOG4105CI3	gtp-binding protein typa
FCN51_RS04990	ENOG4105CA9	Pyruvate kinase
FCN51_RS05000	ENOG4105D06	uba thif-type nad fad binding protein
FCN51_RS05030	ENOG4105EPD	Oligopeptide transporter, Opt family
FCN51_RS05045	ENOG4105EV9	Alpha Beta Hydrolase
FCN51_RS05050	ENOG4105DZ0	fad dependent oxidoreductase
FCN51_RS05055	ENOG4105PGM	cation diffusion facilitator family transporter
FCN51_RS05070	ENOG4105CKI	cobalamin synthesis protein
FCN51_RS05080	ENOG4105CEP	NADH dehydrogenase
FCN51_RS05090	ENOG4105VN1	Heat shock protein
FCN51_RS05095	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
FCN51_RS05100	ENOG4105CPP	Dehydrogenase, E1 component
FCN51_RS05105	ENOG4107R0V	Pyruvate dehydrogenase
FCN51_RS05115	ENOG4105CJ3	phosphate transporter
FCN51_RS05120	ENOG4105CSR	polyphosphate kinase 2
FCN51_RS05135	ENOG4105TW1	Carbohydrate-selective porin OprB
FCN51_RS05165	ENOG4105TPV	
FCN51_RS05180	ENOG4105CHR	reductase
FCN51_RS05185	ENOG4105C1G	acyl-Coa dehydrogenase
FCN51_RS05195	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
FCN51_RS05220	ENOG4105C9K	Endothelin-converting enzyme 1
FCN51_RS05260	ENOG4105EMU	Dehydrogenase
FCN51_RS05265	ENOG4105KPV	Transcriptional regulator
FCN51_RS05305	ENOG4105EEQ	Na H antiporter
FCN51_RS05425	ENOG4105C72	UPF0176 protein
FCN51_RS05560	ENOG4105E0K	tonB-dependent siderophore receptor
FCN51_RS05705	ENOG4105C26	Dehydrogenase
FCN51_RS05750	ENOG410630Q	Methylamine utilization
FCN51_RS05780	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FCN51_RS05810	ENOG4105E0X	reductase
FCN51_RS05815	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FCN51_RS05835	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FCN51_RS05840	ENOG4105RD7	BadF BadG BcrA BcrD
FCN51_RS05845	ENOG4105E2D	ec 3.2.1.52
FCN51_RS05850	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
FCN51_RS05855	ENOG4105EHG	Permease protein
FCN51_RS05865	ENOG4105D05	Receptor
FCN51_RS05870	ENOG4105EEQ	Na H antiporter
FCN51_RS05880	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
FCN51_RS05920	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FCN51_RS05965	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FCN51_RS05975	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
FCN51_RS05980	ENOG4105E4C	Lytic transglycosylase catalytic
FCN51_RS05990	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FCN51_RS06005	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FCN51_RS06025	ENOG410901P	UPF0249 protein
FCN51_RS06040	ENOG4105DHP	deoxycytidine triphosphate deaminase
FCN51_RS06045	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FCN51_RS06060	ENOG4107QR9	Iron-sulfur cluster binding protein
FCN51_RS06065	ENOG4107R5T	Cysteine-rich domain
FCN51_RS06080	ENOG4105C7K	acetolactate synthase
FCN51_RS06100	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FCN51_RS06110	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FCN51_RS06115	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FCN51_RS06120	ENOG4105C3G	gtp-binding protein
FCN51_RS06125	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FCN51_RS06140	ENOG4105C9M	aspartyl-trna synthetase
FCN51_RS06155	ENOG4105C88	aminopeptidase
FCN51_RS06170	ENOG4105JHE	Major Facilitator Superfamily
FCN51_RS06175	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCN51_RS06180	ENOG4105CR4	methylisocitrate lyase
FCN51_RS06185	ENOG4105BZN	citrate synthase
FCN51_RS06190	ENOG4105DXD	2-methylcitrate dehydratase
FCN51_RS06220	ENOG4105EXC	Acyl-transferase
FCN51_RS06295	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FCN51_RS06305	ENOG4105DXN	mazG family
FCN51_RS06310	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FCN51_RS06315	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
FCN51_RS06330	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
FCN51_RS06340	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
FCN51_RS06345	ENOG4105C37	(CBS) domain
FCN51_RS06350	ENOG4105D6F	Phosphatase
FCN51_RS06370	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
FCN51_RS06375	ENOG4105BZU	Histidine kinase
FCN51_RS06380	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCN51_RS06385	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FCN51_RS06390	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
FCN51_RS06400	ENOG4107EFR	Flavocytochrome c
FCN51_RS06405	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FCN51_RS06410	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FCN51_RS06415	ENOG4107QUT	magnesium and cobalt transport protein CorA
FCN51_RS06435	ENOG41090R7	Ferric uptake
FCN51_RS06445	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FCN51_RS06450	ENOG4108WRK	Transcriptional regulator
FCN51_RS06460	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
FCN51_RS06465	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FCN51_RS06470	ENOG4105DXC	membrane
FCN51_RS06485	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FCN51_RS06490	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FCN51_RS06495	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FCN51_RS06500	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FCN51_RS06505	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FCN51_RS06510	ENOG4105CFG	Acts as a chaperone (By similarity)
FCN51_RS06515	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FCN51_RS06520	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FCN51_RS06525	ENOG4105EB3	Histidine kinase
FCN51_RS06535	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FCN51_RS06540	ENOG4108UJU	UPF0301 protein
FCN51_RS06545	ENOG4105CSR	polyphosphate kinase 2
FCN51_RS06560	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FCN51_RS06565	ENOG4105DZ1	carboxypeptidase
FCN51_RS06570	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FCN51_RS06580	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
FCN51_RS06585	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
FCN51_RS06605	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FCN51_RS06610	ENOG4105EIE	fructose-bisphosphate aldolase
FCN51_RS06635	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FCN51_RS06640	ENOG4105D48	metallophosphoesterase
FCN51_RS06655	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FCN51_RS06670	ENOG4107SFH	ImpB mucB samB family
FCN51_RS06675	ENOG4105C85	amino acid
FCN51_RS06715	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FCN51_RS06725	ENOG4108FN7	Aldo keto reductase
FCN51_RS06740	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
FCN51_RS06745	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
FCN51_RS06750	ENOG4108K4C	ec 3.1.3.12
FCN51_RS06775	ENOG4107RTZ	reductase
FCN51_RS06790	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FCN51_RS06805	ENOG4108V1U	phospholipid-binding protein
FCN51_RS06815	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FCN51_RS06820	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FCN51_RS06825	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FCN51_RS06835	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
FCN51_RS06850	ENOG4108YYQ	gCN5-related N-acetyltransferase
FCN51_RS06855	ENOG4105C5H	ABC transporter
FCN51_RS06865	ENOG4105F0N	pyrophosphate phospho-hydrolase
FCN51_RS06870	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
FCN51_RS06885	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
FCN51_RS06890	ENOG4105D3R	alkyl hydroperoxide reductase
FCN51_RS06930	ENOG4105FBD	synthase
FCN51_RS06935	ENOG4105FE1	phytoene synthase
FCN51_RS06965	ENOG4105Y49	secretion protein, HlyD family
FCN51_RS06990	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FCN51_RS07005	ENOG4108ZZ3	UPF0260 protein
FCN51_RS07075	ENOG4108IUZ	ABC transporter
FCN51_RS07080	ENOG4105C0Z	ABC transporter
FCN51_RS07100	ENOG4105BZU	Histidine kinase
FCN51_RS07110	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
FCN51_RS07150	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FCN51_RS07155	ENOG4105BZS	acriflavin resistance protein
FCN51_RS07160	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FCN51_RS07170	ENOG4107FQ9	ethanolamine ammonia-lyase
FCN51_RS07175	ENOG4105CPD	ethanolamine ammonia-lyase
FCN51_RS07180	ENOG4108R6W	Transcriptional regulator, ARAC family
FCN51_RS07185	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
FCN51_RS07200	ENOG4108I5D	sulfate abc transporter
FCN51_RS07205	ENOG4105ECW	sulfate abc transporter
FCN51_RS07210	ENOG4108IJ6	ABC transporter
FCN51_RS07215	ENOG4105C85	amino acid
FCN51_RS07235	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
FCN51_RS07240	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FCN51_RS07245	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FCN51_RS07250	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FCN51_RS07255	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FCN51_RS07260	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FCN51_RS07265	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FCN51_RS07295	ENOG4107R1I	NAD-dependent malic enzyme
FCN51_RS07305	ENOG4108RHM	integral membrane protein
FCN51_RS07310	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FCN51_RS07325	ENOG4105DP0	ferredoxin-NADP reductase
FCN51_RS07330	ENOG4105DC8	reductase
FCN51_RS07335	ENOG4105CD3	dihydroorotase
FCN51_RS07345	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FCN51_RS07355	ENOG4105ESV	Glycosyl transferase, family 4
FCN51_RS07370	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FCN51_RS07385	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
FCN51_RS07390	ENOG4105CCU	oxidase (Subunit III)
FCN51_RS07405	ENOG4105HFZ	Membrane
FCN51_RS07425	ENOG4108RG0	uracil-dna glycosylase
FCN51_RS07435	ENOG4105DSW	Fusaric acid resistance protein
FCN51_RS07440	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FCN51_RS07450	ENOG4105C2C	drug resistance transporter, Bcr CflA
FCN51_RS07460	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
FCN51_RS07465	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FCN51_RS07485	ENOG4105CJN	penicillin-binding protein
FCN51_RS07490	ENOG4105CNI	cell division protein FtsW
FCN51_RS07530	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
FCN51_RS07535	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FCN51_RS07540	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FCN51_RS07555	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FCN51_RS07560	ENOG4105CAT	Cytidine monophosphate kinase
FCN51_RS07565	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FCN51_RS07575	ENOG4105KRF	dihydroneopterin aldolase
FCN51_RS07580	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
FCN51_RS07585	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FCN51_RS07590	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FCN51_RS07595	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FCN51_RS07615	ENOG4105CE4	GlcNAc 6-P deacetylase
FCN51_RS07620	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
FCN51_RS07625	ENOG4105DJ9	glucan biosynthesis protein
FCN51_RS07630	ENOG4105F4R	Transcriptional regulator mode
FCN51_RS07645	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FCN51_RS07655	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FCN51_RS07675	ENOG4105BZA	Phosphoglycerate kinase
FCN51_RS07705	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
FCN51_RS07710	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FCN51_RS07715	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FCN51_RS07720	ENOG4105W8H	transhydrogenase (subunit alpha
FCN51_RS07725	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FCN51_RS07735	ENOG4105C26	Dehydrogenase
FCN51_RS07740	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FCN51_RS07755	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FCN51_RS07765	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
FCN51_RS07775	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
FCN51_RS07805	ENOG4105K63	Thioredoxin
FCN51_RS07810	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCN51_RS07815	ENOG4105W49	UPF0434 protein
FCN51_RS07825	ENOG4105CZQ	inner membrane transport protein YdhC
FCN51_RS07835	ENOG4108UPT	UPF0178 protein
FCN51_RS07845	ENOG4108UHJ	MAF-like protein
FCN51_RS07850	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FCN51_RS07855	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
FCN51_RS07860	ENOG4108YXA	Membrane
FCN51_RS07875	ENOG4108URH	decarboxylase
FCN51_RS07895	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FCN51_RS07900	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FCN51_RS07905	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FCN51_RS07910	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
FCN51_RS07915	ENOG4107QJE	Chromosome Partitioning Protein
FCN51_RS07920	ENOG4105FA0	parb-like partition protein
FCN51_RS07940	ENOG4105M0C	cytoplasmic protein
FCN51_RS07950	ENOG41069NU	Nitroreductase
FCN51_RS07955	ENOG4105K59	histidine triad (HIT) protein
FCN51_RS07960	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
FCN51_RS07965	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FCN51_RS07970	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FCN51_RS07975	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FCN51_RS07980	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FCN51_RS07995	ENOG4107S6X	Glycosyl transferase, family 2
FCN51_RS08015	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCN51_RS08035	ENOG4105II7	pyrroline-5-carboxylate reductase
FCN51_RS08050	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FCN51_RS08065	ENOG4105D8X	mechanosensitive ion channel
FCN51_RS08075	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
FCN51_RS08080	ENOG4105EIN	peptidylprolyl cis-trans isomerase
FCN51_RS08085	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FCN51_RS08090	ENOG4105CDY	transcriptional regulatory protein
FCN51_RS08095	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FCN51_RS08100	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FCN51_RS08105	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FCN51_RS08110	ENOG4107YD3	Thioesterase
FCN51_RS08115	ENOG4105E02	MotA TolQ exbB proton channel
FCN51_RS08120	ENOG4108ZZF	transport protein (ExbD)
FCN51_RS08130	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FCN51_RS08135	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FCN51_RS08145	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FCN51_RS08150	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FCN51_RS08160	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FCN51_RS08165	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
FCN51_RS08170	ENOG4108E87	P-loop hydrolase UPF0079
FCN51_RS08185	ENOG4105K63	Thioredoxin
FCN51_RS08195	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FCN51_RS08205	ENOG4105C8N	cysteinyl-tRNA synthetase
FCN51_RS08215	ENOG4105DHZ	alpha beta
FCN51_RS08220	ENOG4105C3J	Cysteine desulfurase
FCN51_RS08225	ENOG4105C3J	Cysteine desulfurase
FCN51_RS08235	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FCN51_RS08245	ENOG4105E2K	Glycosyl transferase (Group 1
FCN51_RS08255	ENOG4105CNU	cell division protein FtsK
FCN51_RS08260	ENOG4108RT7	Glycosyl transferase, family 2
FCN51_RS08290	ENOG4108TGR	phosphatase
FCN51_RS08295	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
FCN51_RS08300	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FCN51_RS08320	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FCN51_RS08330	ENOG4108UUM	single-stranded DNA-binding protein
FCN51_RS08335	ENOG4106H78	methyltransferase
FCN51_RS08340	ENOG4105FE9	pseudouridine synthase
FCN51_RS08345	ENOG4108Z86	Glutamine amidotransferase
FCN51_RS08350	ENOG4108Z6B	deaminase
FCN51_RS08355	ENOG4105C0H	protease
FCN51_RS08360	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FCN51_RS08370	ENOG4105D4P	Coproporphyrinogen iii oxidase
FCN51_RS08380	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FCN51_RS08385	ENOG4105TPV	
FCN51_RS08390	ENOG4105C10	Electron transfer flavoprotein
FCN51_RS08450	ENOG4105C8T	Leucyl-tRNA synthetase
FCN51_RS08455	ENOG4105TXM	Domain of unknown function (DUF3576)
FCN51_RS08475	ENOG4105CEN	a g-specific adenine glycosylase
FCN51_RS08480	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FCN51_RS08485	ENOG4105CSM	endonuclease III
FCN51_RS08490	ENOG4105BZ1	(ABC) transporter
FCN51_RS08500	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FCN51_RS08505	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FCN51_RS08510	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FCN51_RS08515	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FCN51_RS08525	ENOG4108JPW	Aminotransferase
FCN51_RS08535	ENOG4105TW1	Carbohydrate-selective porin OprB
FCN51_RS08550	ENOG4105TW1	Carbohydrate-selective porin OprB
FCN51_RS08575	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FCN51_RS08580	ENOG4105C54	Major Facilitator superfamily
FCN51_RS08585	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FCN51_RS08590	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FCN51_RS08595	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FCN51_RS08605	ENOG4107U9T	Pfam:Ribonuclease_BN
FCN51_RS08610	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FCN51_RS08620	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
FCN51_RS08625	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
FCN51_RS08630	ENOG4107QM5	aconitate hydratase
FCN51_RS08635	ENOG4105CDA	abc transporter atp-binding protein
FCN51_RS08645	ENOG4105EXG	Transcriptional regulator
FCN51_RS08655	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
FCN51_RS08665	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FCN51_RS08680	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FCN51_RS08685	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FCN51_RS08695	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FCN51_RS08700	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FCN51_RS08710	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
FCN51_RS08715	ENOG4107GFK	fumarate
FCN51_RS08730	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
FCN51_RS08770	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
FCN51_RS08780	ENOG4105C01	Dihydroxy-acid dehydratase
FCN51_RS08785	ENOG4105C8U	phosphate abc transporter
FCN51_RS08790	ENOG4105E2Z	phosphate ABC transporter (Permease
FCN51_RS08795	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FCN51_RS08815	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FCN51_RS08820	ENOG4108UJD	30S ribosomal protein S9
FCN51_RS08835	ENOG4105C1J	atp-dependent rna helicase
FCN51_RS08850	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FCN51_RS08855	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FCN51_RS08860	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FCN51_RS08865	ENOG4107PQ6	Inherit from NOG: atp synthase
FCN51_RS08890	ENOG4105CKK	Glycosyl transferase, family 2
FCN51_RS08895	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
FCN51_RS08905	ENOG4105F1S	paraquat-inducible protein a
FCN51_RS08910	ENOG4105DY2	Paraquat-inducible protein b
FCN51_RS08920	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FCN51_RS08935	ENOG4105C3R	Methionine synthase
FCN51_RS08980	ENOG4105DY2	Paraquat-inducible protein b
FCN51_RS08985	ENOG4105DHJ	ABC, transporter
FCN51_RS08995	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FCN51_RS09000	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FCN51_RS09005	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FCN51_RS09020	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FCN51_RS09025	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FCN51_RS09030	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FCN51_RS09040	ENOG4105EXG	Transcriptional regulator
FCN51_RS09050	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
FCN51_RS09055	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
FCN51_RS09060	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FCN51_RS09065	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FCN51_RS09070	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FCN51_RS09090	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
FCN51_RS09100	ENOG4105C5X	domain protein
FCN51_RS09150	ENOG4108VHT	MarR family transcriptional regulator
FCN51_RS09155	ENOG4105MSY	salicylate hydroxylase
FCN51_RS09160	ENOG4108XHQ	(2Fe-2S)-binding domain protein
FCN51_RS09165	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
FCN51_RS09175	ENOG4108UAU	isochorismatase
FCN51_RS09185	ENOG4105RE0	Asp Glu hydantoin racemase
FCN51_RS09190	ENOG4105CSP	Major Facilitator Superfamily
FCN51_RS09245	ENOG4105D3R	alkyl hydroperoxide reductase
FCN51_RS09250	ENOG41080HT	Transcriptional regulator, arsr family
FCN51_RS09255	ENOG4108R3E	Dna-3-methyladenine glycosylase i
FCN51_RS09265	ENOG4105KUZ	arsenate reductase
FCN51_RS09270	ENOG4108UQY	Iron-storage protein
FCN51_RS09300	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
FCN51_RS09305	ENOG4108YZ9	Urea amidohydrolase subunit gamma
FCN51_RS09310	ENOG4105KI2	Urea amidohydrolase subunit beta
FCN51_RS09315	ENOG4105CQM	Urea amidohydrolase subunit alpha
FCN51_RS09320	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
FCN51_RS09325	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
FCN51_RS09330	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
FCN51_RS09345	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCN51_RS09350	ENOG4105BZU	Histidine kinase
FCN51_RS09360	ENOG4105C32	Amino acid ABC transporter (Permease)
FCN51_RS09370	ENOG4105C0Z	ABC transporter
FCN51_RS09375	ENOG4108IV0	ABC, transporter
FCN51_RS09395	ENOG4105CSA	Coproporphyrinogen iii oxidase
FCN51_RS09400	ENOG4105DFH	Transport of potassium into the cell (By similarity)
FCN51_RS09405	ENOG4105DFA	alanine racemase domain protein
FCN51_RS09410	ENOG4105CPQ	Dehydrogenase
FCN51_RS09415	ENOG4105CMQ	Chloride channel
FCN51_RS09435	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
FCN51_RS09440	ENOG4105E66	phosphoriboisomerase A
FCN51_RS09445	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
FCN51_RS09450	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
FCN51_RS09455	ENOG4108J5G	6-phosphogluconate dehydrogenase
FCN51_RS09460	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FCN51_RS09475	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FCN51_RS09490	ENOG4105KK4	UPF0060 membrane protein
FCN51_RS09515	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FCN51_RS09525	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FCN51_RS09540	ENOG4105DAA	L-lactate
FCN51_RS09545	ENOG4105E4C	Lytic transglycosylase catalytic
FCN51_RS09550	ENOG4107QNK	)-transporter
FCN51_RS09565	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FCN51_RS09570	ENOG4105C6T	cysteine synthase
FCN51_RS09585	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
FCN51_RS09600	ENOG4105MYN	Zinc uptake regulation protein
FCN51_RS09610	ENOG4105D5T	phosphonate abc transporter
FCN51_RS09615	ENOG4105FAV	ABC, transporter
FCN51_RS09620	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
FCN51_RS09625	ENOG4105CGU	Enoyl-CoA hydratase
FCN51_RS09630	ENOG4106HK8	GPR1 FUN34 yaaH family protein
FCN51_RS09635	ENOG4105DSW	Fusaric acid resistance protein
FCN51_RS09660	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FCN51_RS09670	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FCN51_RS09675	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FCN51_RS09680	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
FCN51_RS09690	ENOG4105EFT	decarboxylase
FCN51_RS09695	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
FCN51_RS09700	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
FCN51_RS09710	ENOG4105F27	Major Facilitator
FCN51_RS09745	ENOG4105CK2	sodium dicarboxylate symporter
FCN51_RS09765	ENOG4108ZZF	transport protein (ExbD)
FCN51_RS09775	ENOG4108IU3	tonb-dependent siderophore receptor
FCN51_RS09790	ENOG4107E2E	PKHD-type hydroxylase
FCN51_RS09805	ENOG4105C26	Dehydrogenase
FCN51_RS09810	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FCN51_RS09815	ENOG4107TYH	extracellular solute-binding protein family 1
FCN51_RS09820	ENOG4105D81	ABC transporter, permease
FCN51_RS09825	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
FCN51_RS09840	ENOG4105JHE	Major Facilitator Superfamily
FCN51_RS09850	ENOG4105C26	Dehydrogenase
FCN51_RS09870	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
FCN51_RS09880	ENOG4105CHR	reductase
FCN51_RS09895	ENOG4105MP9	class II Aldolase
FCN51_RS09900	ENOG4108VQN	4-hydroxyphenylacetate 3-monooxygenase reductase
FCN51_RS09905	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FCN51_RS09910	ENOG41090MY	MarR family Transcriptional regulator
FCN51_RS09925	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FCN51_RS09930	ENOG4105CQB	FAD linked oxidase domain protein
FCN51_RS09935	ENOG4105D01	(LipO)protein
FCN51_RS09940	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FCN51_RS09945	ENOG4108UMI	ABC transporter, permease
FCN51_RS09955	ENOG41067QW	Transcriptional regulator
FCN51_RS09965	ENOG4105CF1	Alkylated DNA repair protein
FCN51_RS09990	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
FCN51_RS10000	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FCN51_RS10005	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FCN51_RS10015	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FCN51_RS10025	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FCN51_RS10030	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FCN51_RS10045	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
FCN51_RS10050	ENOG4105CD3	dihydroorotase
FCN51_RS10065	ENOG4105BZ8	glutamate synthase
FCN51_RS10070	ENOG4107SJI	Dehydrogenase
FCN51_RS10075	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
FCN51_RS10090	ENOG41090U3	tautomerase
FCN51_RS10110	ENOG4105C85	amino acid
FCN51_RS10125	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FCN51_RS10130	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FCN51_RS10140	ENOG4105CSH	Transporter
FCN51_RS10155	ENOG4105C2M	dna polymerase I
FCN51_RS10160	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FCN51_RS10165	ENOG4105CNG	UPF0061 protein
FCN51_RS10170	ENOG4105E0A	ABC, transporter
FCN51_RS10175	ENOG4105EHG	Permease protein
FCN51_RS10185	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FCN51_RS10190	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FCN51_RS10195	ENOG4105CBT	Fructose-1,6-bisphosphatase
FCN51_RS10200	ENOG4105D6E	homoserine dehydrogenase
FCN51_RS10205	ENOG4105CHM	Aminotransferase
FCN51_RS10215	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FCN51_RS10225	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
FCN51_RS10230	ENOG4105Z85	coenzyme PQQ synthesis
FCN51_RS10235	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
FCN51_RS10240	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
FCN51_RS10265	ENOG4105CGK	Exodeoxyribonuclease III
FCN51_RS10270	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
FCN51_RS10275	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FCN51_RS10280	ENOG4105C75	arginyL-tRNA synthetase
FCN51_RS10290	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
FCN51_RS10295	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FCN51_RS10300	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
FCN51_RS10305	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FCN51_RS10310	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FCN51_RS10320	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FCN51_RS10505	ENOG4108N0N	Phage Terminase Large Subunit
FCN51_RS10600	ENOG41068WC	Domain of unknown function (DUF955)
FCN51_RS10740	ENOG4105DSW	Fusaric acid resistance protein
FCN51_RS10745	ENOG4107RSM	transcriptional regulator
FCN51_RS10820	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FCN51_RS10835	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FCN51_RS10840	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FCN51_RS10845	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FCN51_RS10870	ENOG4105CHM	Aminotransferase
FCN51_RS10880	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FCN51_RS10900	ENOG4107R7A	Allophanate hydrolase subunit 2
FCN51_RS10905	ENOG4105E7W	lamb ycsf family protein
FCN51_RS10950	ENOG4105CC0	LysR family Transcriptional regulator
FCN51_RS10955	ENOG4105EUB	pirin domain protein
FCN51_RS10960	ENOG4108YYH	Nadph-dependent fmn reductase
FCN51_RS10970	ENOG4105F27	Major Facilitator
FCN51_RS10975	ENOG4105C26	Dehydrogenase
FCN51_RS10985	ENOG4105CEP	NADH dehydrogenase
FCN51_RS10990	ENOG4108WUH	Transcriptional regulator, TetR family
FCN51_RS11005	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FCN51_RS11030	ENOG4105CXG	d-lactate dehydrogenase
FCN51_RS11060	ENOG4105VYE	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
FCN51_RS11070	ENOG4108Z03	MAF-like protein
FCN51_RS11075	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FCN51_RS11080	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FCN51_RS11085	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FCN51_RS11090	ENOG4105C03	ribonuclease
FCN51_RS11095	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
FCN51_RS11140	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FCN51_RS11145	ENOG4105CUV	Homoserine Kinase
FCN51_RS11150	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FCN51_RS11165	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FCN51_RS11185	ENOG4105C22	threonyL-tRNA synthetase
FCN51_RS11190	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FCN51_RS11200	ENOG41062D9	Histidine kinase
FCN51_RS11205	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FCN51_RS11215	ENOG4105C5H	ABC transporter
FCN51_RS11220	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FCN51_RS11225	ENOG4105EPH	radical SAM domain protein
FCN51_RS11250	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
FCN51_RS11255	ENOG4105CHM	Aminotransferase
FCN51_RS11260	ENOG4105CHM	Aminotransferase
FCN51_RS11275	ENOG4105M4H	endoribonuclease L-psp
FCN51_RS11280	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
FCN51_RS11285	ENOG4105C0B	DNA polymerase III (alpha subunit)
FCN51_RS11290	ENOG4105CRQ	synthase (Component I)
FCN51_RS11315	ENOG4105CE9	30S ribosomal protein S2
FCN51_RS11320	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FCN51_RS11325	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
FCN51_RS11330	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FCN51_RS11335	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
FCN51_RS11340	ENOG4105D52	delta-aminolevulinic acid dehydratase
FCN51_RS11345	ENOG4105CUB	amino acid
FCN51_RS11350	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FCN51_RS11355	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
FCN51_RS11370	ENOG4105C1J	atp-dependent rna helicase
FCN51_RS11385	ENOG4105EAC	phosphoserine phosphatase
FCN51_RS11390	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FCN51_RS11395	ENOG4105C7K	acetolactate synthase
FCN51_RS11400	ENOG4108ZP8	Acetolactate synthase small subunit
FCN51_RS11405	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FCN51_RS11415	ENOG4105E3B	Multicopper oxidase
FCN51_RS11425	ENOG4105C59	p-type ATPase
FCN51_RS11435	ENOG4108RWI	nicotinamidase
FCN51_RS11440	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FCN51_RS11455	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
FCN51_RS11475	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FCN51_RS11480	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FCN51_RS11485	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FCN51_RS11490	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FCN51_RS11495	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FCN51_RS11500	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCN51_RS11510	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FCN51_RS11515	ENOG4108UFP	Essential cell division protein (By similarity)
FCN51_RS11520	ENOG4105CPF	Cell wall formation (By similarity)
FCN51_RS11525	ENOG4105D4A	Cell wall formation (By similarity)
FCN51_RS11530	ENOG4105DFU	Cell wall formation (By similarity)
FCN51_RS11545	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FCN51_RS11550	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FCN51_RS11560	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FCN51_RS11575	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FCN51_RS11580	ENOG4107YUR	Cell division protein mraZ
FCN51_RS11600	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
FCN51_RS11605	ENOG4105Y2X	UPF0335 protein
FCN51_RS11615	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FCN51_RS11620	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FCN51_RS11625	ENOG4105K46	50S ribosomal protein l27
FCN51_RS11630	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FCN51_RS11710	ENOG4105F6A	helicase
FCN51_RS11715	ENOG4105D85	methylase
FCN51_RS11720	ENOG4105DFP	Integrase
FCN51_RS11770	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FCN51_RS11775	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FCN51_RS11780	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FCN51_RS11790	ENOG4108R6K	riboflavin synthase, subunit alpha
FCN51_RS11795	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FCN51_RS11800	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FCN51_RS11830	ENOG4105Y49	secretion protein, HlyD family
FCN51_RS11860	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FCN51_RS11870	ENOG4105EUJ	GTP cyclohydrolase i
FCN51_RS11875	ENOG4105NWN	ApaG protein
FCN51_RS11890	ENOG4105M6F	mutator MutT protein
FCN51_RS11910	ENOG4105C25	Primosomal protein n'
FCN51_RS11915	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCN51_RS11935	ENOG4105BZU	Histidine kinase
FCN51_RS11975	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FCN51_RS11980	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FCN51_RS11995	ENOG4105DVT	helicase
FCN51_RS12000	ENOG4105ECY	inositol monophosphatase
FCN51_RS12005	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FCN51_RS12025	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
FCN51_RS12030	ENOG4105D7W	serine acetyltransferase
FCN51_RS12035	ENOG4108YZA	Nitrogen regulatory protein pii
FCN51_RS12040	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FCN51_RS12055	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FCN51_RS12065	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
FCN51_RS12110	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FCN51_RS12135	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FCN51_RS12140	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
FCN51_RS12145	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FCN51_RS12160	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FCN51_RS12175	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
FCN51_RS12180	ENOG4105CHH	sulfate transporter
FCN51_RS12185	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FCN51_RS12190	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FCN51_RS12195	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
FCN51_RS12200	ENOG4105CAQ	asparagine synthetase
FCN51_RS12205	ENOG4107TYR	Glycosyl Transferase
FCN51_RS12225	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FCN51_RS12230	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FCN51_RS12240	ENOG4105D1K	glutamate--cysteine ligase
FCN51_RS12260	ENOG4105D1H	recombination factor protein RarA
FCN51_RS12265	ENOG4105EI2	Pseudouridine synthase
FCN51_RS12290	ENOG4105K5M	30s ribosomal protein S16
FCN51_RS12295	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FCN51_RS12300	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FCN51_RS12305	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FCN51_RS12310	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FCN51_RS12315	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FCN51_RS12320	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FCN51_RS12325	ENOG4105K5G	30S ribosomal protein S21
FCN51_RS12330	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FCN51_RS12340	ENOG41090HR	transcriptional regulator
FCN51_RS12345	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FCN51_RS12350	ENOG4105E0F	Histidine kinase
FCN51_RS12365	ENOG41082R8	50S ribosomal protein l32
FCN51_RS12370	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FCN51_RS12375	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FCN51_RS12380	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCN51_RS12385	ENOG4105WJX	transcriptional regulator MERR family
FCN51_RS12400	ENOG4105CJR	Integral membrane protein (MviN
FCN51_RS12410	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FCN51_RS12420	ENOG4108PZW	LysR family Transcriptional regulator
FCN51_RS12425	ENOG4105C3M	thioredoxin reductase
FCN51_RS12430	ENOG4105F7P	transcriptional regulator AsnC family
FCN51_RS12450	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FCN51_RS12455	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FCN51_RS12460	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FCN51_RS12475	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
FCN51_RS12480	ENOG4105C1V	Peptidase, M16
FCN51_RS12485	ENOG4105D98	threonine synthase
FCN51_RS12495	ENOG4105CTD	carboxy-peptidase
FCN51_RS12505	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FCN51_RS12510	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
FCN51_RS12520	ENOG4108JJ7	ABC transporter
FCN51_RS12530	ENOG4105KDC	50s ribosomal protein l28
FCN51_RS12540	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FCN51_RS12550	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
FCN51_RS12555	ENOG4106BRA	Membrane
FCN51_RS12575	ENOG4105JRK	feS assembly protein SufD
FCN51_RS12580	ENOG4105C9B	Cysteine desulfurase
FCN51_RS12590	ENOG4105VG1	fes assembly suf system protein
FCN51_RS12595	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
FCN51_RS12600	ENOG4107QS4	23S rRNA
FCN51_RS12605	ENOG4105C1J	atp-dependent rna helicase
FCN51_RS12615	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FCN51_RS12625	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FCN51_RS12630	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FCN51_RS12635	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FCN51_RS12640	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FCN51_RS12645	ENOG4105K70	DNA-binding protein
FCN51_RS12665	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCN51_RS12670	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FCN51_RS12675	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCN51_RS12680	ENOG4105GKE	subunit e
FCN51_RS12685	ENOG4107QIZ	NADH dehydrogenase
FCN51_RS12695	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FCN51_RS12700	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCN51_RS12705	ENOG4105DF2	NADH dehydrogenase subunit j
FCN51_RS12710	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCN51_RS12715	ENOG4105D65	subunit l
FCN51_RS12720	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FCN51_RS12725	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FCN51_RS12730	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FCN51_RS12740	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FCN51_RS12750	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FCN51_RS12770	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FCN51_RS12775	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FCN51_RS12780	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FCN51_RS12805	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
FCN51_RS12820	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FCN51_RS12830	ENOG4107RCI	amp-dependent synthetase and ligase
FCN51_RS12915	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
FCN51_RS12940	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FCN51_RS12950	ENOG41061A5	transposase
FCN51_RS12960	ENOG4105E5H	Transposase
FCN51_RS12990	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FCN51_RS13035	ENOG4105ETX	regulatoR
FCN51_RS13040	ENOG4105DHQ	Histidine kinase
FCN51_RS13070	ENOG4108VN5	Inherit from COG: PepSY-associated TM helix
FCN51_RS13110	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FCN51_RS13125	ENOG4105CHR	reductase
FCN51_RS13135	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
FCN51_RS13150	ENOG4105CFN	oxalyl-CoA decarboxylase
FCN51_RS13170	ENOG4108302	MgtC SapB transporter
FCN51_RS13180	ENOG4108Z9Z	response to DNA damage stimulus
FCN51_RS13190	ENOG4105DQ4	alcohol dehydrogenase
FCN51_RS13195	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FCN51_RS13205	ENOG4105DDW	LysR family Transcriptional regulator
FCN51_RS13210	ENOG4105C5H	ABC transporter
FCN51_RS13230	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FCN51_RS13245	ENOG4105CEB	Aspartate aminotransferase
FCN51_RS13250	ENOG4105HDK	L-asparaginase
FCN51_RS13265	ENOG4108ESX	Receptor
FCN51_RS13270	ENOG4107E2E	PKHD-type hydroxylase
FCN51_RS13275	ENOG4108JJ9	ABC, transporter
FCN51_RS13280	ENOG4108JJ8	(ABC) transporter
FCN51_RS13285	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FCN51_RS13290	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FCN51_RS13310	ENOG4105D64	Mechanosensitive ion channel
FCN51_RS13335	ENOG4108MI0	Resistance protein
FCN51_RS13340	ENOG4105J12	Multidrug resistance protein mdtN
FCN51_RS13355	ENOG4105NTW	Transcriptional regulator
FCN51_RS13370	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FCN51_RS13415	ENOG4105EA8	2-Nitropropane dioxygenase
FCN51_RS13420	ENOG4108JQ7	(ABC) transporter
FCN51_RS13475	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
FCN51_RS13480	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
FCN51_RS13510	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FCN51_RS13515	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FCN51_RS13575	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FCN51_RS13585	ENOG4105ETS	cytosine purines uracil thiamine allantoin
FCN51_RS13595	ENOG4105C26	Dehydrogenase
FCN51_RS13600	ENOG4105H3G	oxidoreductase
FCN51_RS13620	ENOG4107QZF	nitrite reductase NADPH large subunit
FCN51_RS13640	ENOG4105DHQ	Histidine kinase
FCN51_RS13645	ENOG4105ETX	regulatoR
FCN51_RS13690	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
FCN51_RS13695	ENOG4105XMH	SpoVT AbrB domain protein
FCN51_RS13730	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FCN51_RS13740	ENOG4105K4U	addiction module toxin, RelE StbE family
FCN51_RS13745	ENOG4105EEQ	Na H antiporter
FCN51_RS13755	ENOG41061A5	transposase
FCN51_RS13765	ENOG4105E5H	Transposase
FCN51_RS13795	ENOG4105K78	MarR family Transcriptional regulator
FCN51_RS13845	ENOG4108WUH	Transcriptional regulator, TetR family
FCN51_RS13850	ENOG4108I6A	alcohol dehydrogenase
FCN51_RS13855	ENOG4105C26	Dehydrogenase
FCN51_RS13875	ENOG41060A7	DNA polymerase beta domain protein region
FCN51_RS13885	ENOG4105CVR	type I restriction-modification system
FCN51_RS13910	ENOG4105H3G	oxidoreductase
FCN51_RS13915	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
FCN51_RS13930	ENOG4105DZ2	Transcriptional regulator
FCN51_RS13935	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FCN51_RS13940	ENOG4105EQR	Transposase IS116 IS110 IS902
FCN51_RS13970	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FCN51_RS14005	ENOG4105CCI	Myosin-Cross-Reactive Antigen
FCN51_RS14015	ENOG4105K4U	addiction module toxin, RelE StbE family
FCN51_RS14055	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FCN51_RS14060	ENOG4105H3G	oxidoreductase
FCN51_RS14070	ENOG4108TJN	glycosyl transferase group 1
FCN51_RS14100	ENOG4107SQD	Transcriptional regulator, GntR family
FCN51_RS14110	ENOG4106NZI	LysR family Transcriptional regulator
FCN51_RS14200	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FCN51_RS14210	ENOG4105K78	MarR family Transcriptional regulator