locus-tag	class	description
FCN51_RS00005	COG0629	single-stranded DNA binding
FCN51_RS00060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FCN51_RS00085	COG3550	peptidyl-serine autophosphorylation
FCN51_RS00170	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FCN51_RS00255	COG1196	nuclear chromosome segregation
FCN51_RS00320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FCN51_RS00445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FCN51_RS00445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FCN51_RS00470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FCN51_RS00540	COG0745	RESPONSE REGULATOR receiver
FCN51_RS00545	COG0587	DNA-directed DNA polymerase activity
FCN51_RS00550	COG0210	DNA helicase
FCN51_RS00645	COG0776	regulation of translation
FCN51_RS00655	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FCN51_RS00720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FCN51_RS00740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FCN51_RS00820	COG0194	GDP metabolic process
FCN51_RS00865	COG2176	DNA-directed DNA polymerase activity
FCN51_RS00890	COG3750	Belongs to the UPF0335 family
FCN51_RS00895	COG0840	transmembrane signaling receptor activity
FCN51_RS00900	COG1749	Flagellar hook protein flgE
FCN51_RS00905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FCN51_RS00915	COG1987	bacterial-type flagellum assembly
FCN51_RS00935	COG1815	bacterial-type flagellum-dependent cell motility
FCN51_RS00940	COG1558	bacterial-type flagellum-dependent cell motility
FCN51_RS00945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FCN51_RS00975	COG4786	Flagellar basal body rod
FCN51_RS00980	COG4786	Flagellar basal body rod
FCN51_RS00990	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FCN51_RS01005	COG1766	The M ring may be actively involved in energy transduction
FCN51_RS01010	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FCN51_RS01020	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FCN51_RS01030	COG1338	Plays a role in the flagellum-specific transport system
FCN51_RS01040	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FCN51_RS01055	COG1706	bacterial-type flagellum-dependent cell motility
FCN51_RS01060	COG3951	Flagellar rod assembly protein muramidase FlgJ
FCN51_RS01085	COG1157	protein secretion by the type III secretion system
FCN51_RS01100	COG1360	Flagellar Motor Protein
FCN51_RS01105	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FCN51_RS01115	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FCN51_RS01125	COG0776	regulation of translation
FCN51_RS01235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FCN51_RS01455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FCN51_RS01485	COG3550	peptidyl-serine autophosphorylation
FCN51_RS01575	COG1857	crispr-associated protein
FCN51_RS01595	COG0557	exoribonuclease II activity
FCN51_RS01650	COG0840	transmembrane signaling receptor activity
FCN51_RS01700	COG4974	Belongs to the 'phage' integrase family
FCN51_RS01710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FCN51_RS01725	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FCN51_RS01885	COG0187	DNA topoisomerase II activity
FCN51_RS01890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FCN51_RS01920	COG0306	phosphate transporter
FCN51_RS01970	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FCN51_RS01980	COG0675	Transposase, IS605 OrfB family
FCN51_RS02040	COG0745	RESPONSE REGULATOR receiver
FCN51_RS02045	COG2201	protein-glutamate methylesterase activity
FCN51_RS02050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FCN51_RS02055	COG0835	chemotaxis
FCN51_RS02060	COG0643	Histidine kinase
FCN51_RS02060	COG2198	Histidine kinase
FCN51_RS02065	COG0745	RESPONSE REGULATOR receiver
FCN51_RS02105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FCN51_RS02110	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FCN51_RS02115	COG0592	DNA-directed DNA polymerase activity
FCN51_RS02120	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FCN51_RS02125	COG0187	DNA topoisomerase II activity
FCN51_RS02130	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FCN51_RS02135	COG0504	CTP synthase activity
FCN51_RS02145	COG0149	triose-phosphate isomerase activity
FCN51_RS02155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FCN51_RS02165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FCN51_RS02170	COG0134	indole-3-glycerol-phosphate synthase activity
FCN51_RS02175	COG0315	cyclic pyranopterin monophosphate synthase activity
FCN51_RS02180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FCN51_RS02185	COG0508	dehydrogenase complex catalyzes the overall conversion of
FCN51_RS02185	COG0022	dehydrogenase e1 component
FCN51_RS02190	COG0508	dehydrogenase complex catalyzes the overall conversion of
FCN51_RS02195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FCN51_RS02200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FCN51_RS02215	COG1546	Belongs to the CinA family
FCN51_RS02230	COG0861	Integral membrane protein TerC family
FCN51_RS02235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FCN51_RS02240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FCN51_RS02245	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FCN51_RS02255	COG0047	phosphoribosylformylglycinamidine synthase activity
FCN51_RS02260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FCN51_RS02265	COG0271	Belongs to the BolA IbaG family
FCN51_RS02270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FCN51_RS02285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FCN51_RS02295	COG0628	permease
FCN51_RS02300	COG2897	thiosulfate sulfurtransferase activity
FCN51_RS02305	COG0626	cystathionine gamma-synthase activity
FCN51_RS02310	COG0606	chelatase, subunit chli
FCN51_RS02315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FCN51_RS02325	COG3474	cytochrome
FCN51_RS02330	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FCN51_RS02335	COG0077	Prephenate dehydratase
FCN51_RS02335	COG1605	Chorismate mutase
FCN51_RS02340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FCN51_RS02345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FCN51_RS02350	COG1278	Cold shock
FCN51_RS02385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FCN51_RS02395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FCN51_RS02400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FCN51_RS02405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FCN51_RS02425	COG1663	tetraacyldisaccharide 4'-kinase activity
FCN51_RS02430	COG1519	Transferase
FCN51_RS02440	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FCN51_RS02455	COG0175	sulfate reduction
FCN51_RS02460	COG0175	sulfate reduction
FCN51_RS02470	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FCN51_RS02475	COG0602	queuosine metabolic process
FCN51_RS02480	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FCN51_RS02490	COG0579	oxidoreductase
FCN51_RS02495	COG1764	response to oxidative stress
FCN51_RS02500	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FCN51_RS02505	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FCN51_RS02510	COG0259	pyridoxamine-phosphate oxidase activity
FCN51_RS02540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FCN51_RS02545	COG1686	Belongs to the peptidase S11 family
FCN51_RS02550	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FCN51_RS02555	COG2951	lytic endotransglycosylase activity
FCN51_RS02570	COG0531	amino acid
FCN51_RS02575	COG1968	undecaprenyl-diphosphatase activity
FCN51_RS02595	COG2890	protein-(glutamine-N5) methyltransferase activity
FCN51_RS02605	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FCN51_RS02610	COG0124	histidyl-tRNA synthetase
FCN51_RS02615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FCN51_RS02625	COG2070	2-Nitropropane dioxygenase
FCN51_RS02630	COG0527	aspartate kinase activity
FCN51_RS02635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FCN51_RS02640	COG2706	6-phosphogluconolactonase activity
FCN51_RS02660	COG1040	competence protein
FCN51_RS02665	COG2226	methyltransferase
FCN51_RS02670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FCN51_RS02690	COG0321	lipoyl(octanoyl) transferase activity
FCN51_RS02700	COG0271	Belongs to the BolA IbaG family
FCN51_RS02705	COG0484	heat shock protein binding
FCN51_RS02720	COG0076	glutamate decarboxylase activity
FCN51_RS02725	COG0385	Bile acid
FCN51_RS02735	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FCN51_RS02740	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FCN51_RS02755	COG2022	thiamine diphosphate biosynthetic process
FCN51_RS02775	COG0148	phosphopyruvate hydratase activity
FCN51_RS02785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FCN51_RS02790	COG0303	'Molybdopterin
FCN51_RS02795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FCN51_RS02800	COG4106	trans-aconitate 2-methyltransferase activity
FCN51_RS02800	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FCN51_RS02810	COG0156	8-amino-7-oxononanoate synthase activity
FCN51_RS02815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FCN51_RS02820	COG0314	molybdopterin synthase activity
FCN51_RS02825	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FCN51_RS02840	COG0322	excinuclease ABC activity
FCN51_RS02860	COG0729	surface antigen
FCN51_RS02870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FCN51_RS02880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FCN51_RS02890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FCN51_RS02915	COG1605	Chorismate mutase
FCN51_RS02915	COG0287	Prephenate dehydrogenase
FCN51_RS02920	COG2062	phosphohistidine phosphatase, SixA
FCN51_RS02935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FCN51_RS02940	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FCN51_RS02945	COG0142	geranyltranstransferase activity
FCN51_RS02955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FCN51_RS02960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FCN51_RS02960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FCN51_RS02970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FCN51_RS02975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FCN51_RS02985	COG1970	mechanosensitive ion channel activity
FCN51_RS02990	COG0254	rRNA binding
FCN51_RS02995	COG0071	Belongs to the small heat shock protein (HSP20) family
FCN51_RS03015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FCN51_RS03020	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FCN51_RS03025	COG2003	Belongs to the UPF0758 family
FCN51_RS03030	COG2003	Belongs to the UPF0758 family
FCN51_RS03040	COG2264	protein methyltransferase activity
FCN51_RS03045	COG0006	proline dipeptidase activity
FCN51_RS03050	COG0473	3-isopropylmalate dehydrogenase activity
FCN51_RS03060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FCN51_RS03065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FCN51_RS03090	COG0747	negative chemotaxis
FCN51_RS03100	COG0072	phenylalanine-tRNA ligase activity
FCN51_RS03100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FCN51_RS03105	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FCN51_RS03110	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FCN51_RS03115	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FCN51_RS03120	COG0246	Mannitol dehydrogenase
FCN51_RS03125	COG2010	Cytochrome c
FCN51_RS03125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FCN51_RS03145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FCN51_RS03150	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FCN51_RS03175	COG2884	Cell division ATP-binding protein ftsE
FCN51_RS03190	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FCN51_RS03195	COG3781	membrane
FCN51_RS03200	COG1329	Transcriptional regulator
FCN51_RS03205	COG0457	Tetratricopeptide repeat
FCN51_RS03205	COG0859	PFAM glycosyl transferase family 9
FCN51_RS03215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FCN51_RS03220	COG2081	HI0933 family
FCN51_RS03230	COG0850	regulation of cytokinetic process
FCN51_RS03240	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FCN51_RS03245	COG1802	Transcriptional regulator
FCN51_RS03250	COG1132	(ABC) transporter
FCN51_RS03270	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FCN51_RS03280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FCN51_RS03285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FCN51_RS03290	COG0359	binds to the 23S rRNA
FCN51_RS03295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FCN51_RS03300	COG0360	Binds together with S18 to 16S ribosomal RNA
FCN51_RS03310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FCN51_RS03315	COG0358	DNA primase activity
FCN51_RS03325	COG0505	Belongs to the CarA family
FCN51_RS03330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FCN51_RS03335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FCN51_RS03340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FCN51_RS03345	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FCN51_RS03355	COG0793	Belongs to the peptidase S41A family
FCN51_RS03365	COG1051	belongs to the nudix hydrolase family
FCN51_RS03370	COG2814	Major facilitator Superfamily
FCN51_RS03380	COG1132	(ABC) transporter
FCN51_RS03385	COG0617	tRNA 3'-terminal CCA addition
FCN51_RS03395	COG0714	Associated with various cellular activities
FCN51_RS03420	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FCN51_RS03425	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FCN51_RS03430	COG3237	CsbD-like
FCN51_RS03435	COG0477	Major facilitator Superfamily
FCN51_RS03440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FCN51_RS03445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FCN51_RS03455	COG1538	Outer membrane efflux protein
FCN51_RS03460	COG5487	UPF0391 membrane protein
FCN51_RS03470	COG1116	anion transmembrane transporter activity
FCN51_RS03475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FCN51_RS03485	COG0203	ribosomal protein L17
FCN51_RS03490	COG0202	RNA polymerase activity
FCN51_RS03495	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FCN51_RS03500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FCN51_RS03505	COG0563	adenylate kinase activity
FCN51_RS03515	COG0200	Binds to the 23S rRNA
FCN51_RS03520	COG1841	ribosomal large subunit assembly
FCN51_RS03525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FCN51_RS03530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FCN51_RS03535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FCN51_RS03540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FCN51_RS03545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FCN51_RS03550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FCN51_RS03555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FCN51_RS03560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FCN51_RS03565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FCN51_RS03570	COG0255	Belongs to the universal ribosomal protein uL29 family
FCN51_RS03575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FCN51_RS03580	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FCN51_RS03585	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FCN51_RS03590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FCN51_RS03595	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FCN51_RS03600	COG0089	rRNA binding
FCN51_RS03605	COG0088	Forms part of the polypeptide exit tunnel
FCN51_RS03610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FCN51_RS03615	COG0051	transcription antitermination factor activity, RNA binding
FCN51_RS03620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FCN51_RS03625	COG0049	tRNA binding
FCN51_RS03630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FCN51_RS03635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FCN51_RS03640	COG0085	RNA polymerase activity
FCN51_RS03645	COG0222	ribosome binding
FCN51_RS03650	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FCN51_RS03655	COG0081	regulation of translation
FCN51_RS03660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FCN51_RS03695	COG0477	Major facilitator Superfamily
FCN51_RS03705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FCN51_RS03735	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FCN51_RS03770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FCN51_RS03775	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FCN51_RS03780	COG1138	Cytochrome C-type biogenesis protein
FCN51_RS03785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FCN51_RS03790	COG3088	subunit of a heme lyase
FCN51_RS03815	COG1289	transmembrane transporter activity
FCN51_RS03840	COG1121	(ABC) transporter
FCN51_RS03855	COG0248	Ppx GppA phosphatase
FCN51_RS03860	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FCN51_RS03870	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FCN51_RS03875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FCN51_RS03885	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FCN51_RS03905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FCN51_RS03910	COG0237	dephospho-CoA kinase activity
FCN51_RS03915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FCN51_RS03935	COG0165	Argininosuccinate lyase
FCN51_RS03940	COG0019	diaminopimelate decarboxylase activity
FCN51_RS03950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FCN51_RS03955	COG3591	Belongs to the peptidase S1B family
FCN51_RS03965	COG0640	Transcriptional regulator
FCN51_RS03970	COG1902	pentaerythritol trinitrate reductase activity
FCN51_RS03975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FCN51_RS04025	COG0778	Nitroreductase
FCN51_RS04045	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FCN51_RS04050	COG2857	Cytochrome c1
FCN51_RS04050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FCN51_RS04055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FCN51_RS04060	COG0408	coproporphyrinogen oxidase activity
FCN51_RS04080	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FCN51_RS04090	COG0406	alpha-ribazole phosphatase activity
FCN51_RS04095	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FCN51_RS04105	COG0181	hydroxymethylbilane synthase activity
FCN51_RS04110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FCN51_RS04115	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FCN51_RS04130	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FCN51_RS04135	COG1546	Belongs to the CinA family
FCN51_RS04135	COG1058	Belongs to the CinA family
FCN51_RS04140	COG0825	malonyl-CoA metabolic process
FCN51_RS04145	COG4974	Belongs to the 'phage' integrase family
FCN51_RS04155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FCN51_RS04160	COG2885	chlorophyll binding
FCN51_RS04160	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FCN51_RS04170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FCN51_RS04175	COG0688	phosphatidylethanolamine metabolic process
FCN51_RS04180	COG1183	phosphatidylcholine synthase activity
FCN51_RS04185	COG3260	NADH ubiquinone oxidoreductase 20
FCN51_RS04235	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FCN51_RS04255	COG0508	dehydrogenase complex catalyzes the overall conversion of
FCN51_RS04265	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FCN51_RS04270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FCN51_RS04275	COG2333	competence protein COMEC
FCN51_RS04275	COG0658	competence protein
FCN51_RS04280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FCN51_RS04285	COG0540	Belongs to the ATCase OTCase family
FCN51_RS04290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FCN51_RS04295	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FCN51_RS04300	COG0758	DNA mediated transformation
FCN51_RS04305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FCN51_RS04310	COG0557	exoribonuclease II activity
FCN51_RS04315	COG0793	Belongs to the peptidase S41A family
FCN51_RS04325	COG2885	chlorophyll binding
FCN51_RS04325	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FCN51_RS04330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FCN51_RS04335	COG1959	2 iron, 2 sulfur cluster binding
FCN51_RS04350	COG0187	DNA topoisomerase II activity
FCN51_RS04355	COG5006	permease, DMT superfamily
FCN51_RS04365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FCN51_RS04375	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FCN51_RS04380	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FCN51_RS04385	COG0196	riboflavin kinase activity
FCN51_RS04390	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FCN51_RS04395	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FCN51_RS04400	COG0235	Class ii aldolase
FCN51_RS04405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FCN51_RS04420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FCN51_RS04425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FCN51_RS04435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FCN51_RS04445	COG1643	Atp-dependent helicase
FCN51_RS04455	COG0656	L-ascorbic acid biosynthetic process
FCN51_RS04465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FCN51_RS04475	COG0009	L-threonylcarbamoyladenylate synthase
FCN51_RS04500	COG2096	Adenosyltransferase
FCN51_RS04530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FCN51_RS04555	COG1113	amino acid transport
FCN51_RS04570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FCN51_RS04600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FCN51_RS04605	COG1127	ABC transporter
FCN51_RS04610	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FCN51_RS04610	COG3264	Mechanosensitive ion channel
FCN51_RS04620	COG0305	Participates in initiation and elongation during chromosome replication
FCN51_RS04625	COG2942	2-epimerase
FCN51_RS04630	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FCN51_RS04630	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FCN51_RS04635	COG0194	GDP metabolic process
FCN51_RS04650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FCN51_RS04660	COG0517	IMP dehydrogenase activity
FCN51_RS04660	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FCN51_RS04675	COG1137	ATPase activity
FCN51_RS04680	COG0633	Ferredoxin
FCN51_RS04680	COG3217	Mosc domain protein beta barrel domain protein
FCN51_RS04690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FCN51_RS04710	COG0242	peptide deformylase activity
FCN51_RS04715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FCN51_RS04720	COG0101	tRNA pseudouridine synthase activity
FCN51_RS04730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FCN51_RS04735	COG2171	N-acyltransferase activity
FCN51_RS04740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FCN51_RS04745	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FCN51_RS04750	COG0706	membrane insertase activity
FCN51_RS04755	COG0594	ribonuclease P activity
FCN51_RS04760	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FCN51_RS04770	COG0346	lactoylglutathione lyase activity
FCN51_RS04775	COG3494	Protein of unknown function (DUF1009)
FCN51_RS04780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FCN51_RS04785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FCN51_RS04790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FCN51_RS04805	COG0750	zinc metalloprotease
FCN51_RS04810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FCN51_RS04820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FCN51_RS04825	COG0233	cytoplasmic translational termination
FCN51_RS04830	COG0528	UMP kinase activity
FCN51_RS04835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FCN51_RS04840	COG0571	ribonuclease III activity
FCN51_RS04845	COG0681	Belongs to the peptidase S26 family
FCN51_RS04850	COG0736	holo-[acyl-carrier-protein] synthase activity
FCN51_RS04855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FCN51_RS04860	COG1758	RNA polymerase activity
FCN51_RS04885	COG0513	Belongs to the DEAD box helicase family
FCN51_RS04890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FCN51_RS04890	COG2813	Specifically methylates the guanine in position
FCN51_RS04895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FCN51_RS04900	COG0481	GTPase activity
FCN51_RS04915	COG4993	Dehydrogenase
FCN51_RS04950	COG0538	isocitrate dehydrogenase activity
FCN51_RS04955	COG0492	ferredoxin-NADP+ reductase activity
FCN51_RS04960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FCN51_RS04990	COG0469	pyruvate kinase activity
FCN51_RS05000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FCN51_RS05030	COG1297	OPT oligopeptide transporter protein
FCN51_RS05045	COG0596	Alpha beta hydrolase
FCN51_RS05050	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FCN51_RS05060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FCN51_RS05070	COG0523	cobalamin synthesis protein
FCN51_RS05080	COG1252	NADH dehydrogenase
FCN51_RS05090	COG0071	Belongs to the small heat shock protein (HSP20) family
FCN51_RS05100	COG0022	dehydrogenase e1 component
FCN51_RS05105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FCN51_RS05115	COG0306	phosphate transporter
FCN51_RS05180	COG1028	Short-chain dehydrogenase reductase Sdr
FCN51_RS05185	COG1960	acyl-CoA dehydrogenase activity
FCN51_RS05240	COG1607	acyl-coa hydrolase
FCN51_RS05255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FCN51_RS05260	COG4221	oxidoreductase activity
FCN51_RS05265	COG1959	2 iron, 2 sulfur cluster binding
FCN51_RS05560	COG4774	siderophore transport
FCN51_RS05705	COG1012	belongs to the aldehyde dehydrogenase family
FCN51_RS05780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FCN51_RS05810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FCN51_RS05815	COG0415	Belongs to the DNA photolyase family
FCN51_RS05835	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FCN51_RS05840	COG2971	BadF BadG BcrA BcrD
FCN51_RS05845	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FCN51_RS05850	COG1120	ATPase activity
FCN51_RS05855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FCN51_RS05865	COG4771	TonB-dependent receptor
FCN51_RS05870	COG0025	NhaP-type Na H and K H
FCN51_RS05880	COG1028	Short-chain dehydrogenase reductase Sdr
FCN51_RS05920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FCN51_RS05965	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FCN51_RS05975	COG1573	uracil-dna glycosylase
FCN51_RS05980	COG0741	lytic transglycosylase activity
FCN51_RS05985	COG1253	flavin adenine dinucleotide binding
FCN51_RS05990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FCN51_RS06005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FCN51_RS06025	COG3394	polysaccharide catabolic process
FCN51_RS06040	COG0717	Belongs to the dCTP deaminase family
FCN51_RS06045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FCN51_RS06050	COG0697	spore germination
FCN51_RS06060	COG1139	Iron-sulfur cluster binding protein
FCN51_RS06065	COG0247	lactate metabolic process
FCN51_RS06100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FCN51_RS06105	COG0799	negative regulation of ribosome biogenesis
FCN51_RS06110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FCN51_RS06115	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FCN51_RS06120	COG0012	GTP binding
FCN51_RS06125	COG0193	aminoacyl-tRNA hydrolase activity
FCN51_RS06130	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FCN51_RS06140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FCN51_RS06155	COG2309	aminopeptidase activity
FCN51_RS06165	COG2319	Wd-40 repeat
FCN51_RS06170	COG2814	Major facilitator Superfamily
FCN51_RS06175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FCN51_RS06180	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FCN51_RS06185	COG0372	Belongs to the citrate synthase family
FCN51_RS06190	COG2079	MmgE PrpD family protein
FCN51_RS06295	COG0326	Molecular chaperone. Has ATPase activity
FCN51_RS06305	COG3956	TIGRFAM MazG family protein
FCN51_RS06310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FCN51_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
FCN51_RS06330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FCN51_RS06340	COG0604	alcohol dehydrogenase
FCN51_RS06345	COG1253	flavin adenine dinucleotide binding
FCN51_RS06370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FCN51_RS06380	COG0745	RESPONSE REGULATOR receiver
FCN51_RS06385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FCN51_RS06390	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FCN51_RS06400	COG1053	succinate dehydrogenase
FCN51_RS06405	COG0159	tryptophan synthase activity
FCN51_RS06410	COG0133	tryptophan synthase activity
FCN51_RS06415	COG0598	Magnesium transport protein CorA
FCN51_RS06425	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FCN51_RS06445	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FCN51_RS06450	COG1396	sequence-specific DNA binding
FCN51_RS06460	COG0752	glycyl-tRNA synthetase alpha subunit
FCN51_RS06470	COG0697	spore germination
FCN51_RS06485	COG0138	bifunctional purine biosynthesis protein purh
FCN51_RS06490	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FCN51_RS06495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FCN51_RS06500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FCN51_RS06505	COG0484	heat shock protein binding
FCN51_RS06510	COG0443	Heat shock 70 kDa protein
FCN51_RS06515	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FCN51_RS06520	COG0745	RESPONSE REGULATOR receiver
FCN51_RS06525	COG2205	protein histidine kinase activity
FCN51_RS06535	COG1660	Displays ATPase and GTPase activities
FCN51_RS06540	COG1678	Uncharacterized ACR, COG1678
FCN51_RS06545	COG2326	polyphosphate kinase activity
FCN51_RS06560	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FCN51_RS06565	COG1686	Belongs to the peptidase S11 family
FCN51_RS06570	COG0024	Methionine aminopeptidase
FCN51_RS06580	COG1509	lysine 2,3-aminomutase activity
FCN51_RS06605	COG0352	thiamine-phosphate diphosphorylase activity
FCN51_RS06635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FCN51_RS06640	COG1692	metallophosphoesterase
FCN51_RS06655	COG0167	dihydroorotate dehydrogenase activity
FCN51_RS06670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FCN51_RS06705	COG0612	Peptidase, M16
FCN51_RS06715	COG0556	nucleotide-excision repair
FCN51_RS06725	COG0667	Aldo Keto reductase
FCN51_RS06740	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FCN51_RS06745	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FCN51_RS06750	COG1877	trehalose-phosphatase activity
FCN51_RS06775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FCN51_RS06790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FCN51_RS06805	COG1881	PFAM PEBP family protein
FCN51_RS06815	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FCN51_RS06820	COG0343	queuine tRNA-ribosyltransferase activity
FCN51_RS06825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FCN51_RS06835	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FCN51_RS06855	COG0488	(ABC) transporter
FCN51_RS06865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FCN51_RS06870	COG3384	dioxygenase
FCN51_RS06885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FCN51_RS06890	COG0450	alkyl hydroperoxide reductase
FCN51_RS06900	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FCN51_RS06910	COG0287	Prephenate dehydrogenase
FCN51_RS06920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FCN51_RS06930	COG1562	ergosterol biosynthetic process
FCN51_RS06935	COG1562	ergosterol biosynthetic process
FCN51_RS06940	COG1233	COG1233 Phytoene dehydrogenase and related
FCN51_RS06965	COG1566	PFAM secretion protein HlyD family protein
FCN51_RS06990	COG3842	ATPase activity
FCN51_RS07005	COG2983	Belongs to the UPF0260 family
FCN51_RS07045	COG0789	Transcriptional regulator
FCN51_RS07075	COG1137	ATPase activity
FCN51_RS07080	COG0411	ABC transporter
FCN51_RS07100	COG0784	Response regulator, receiver
FCN51_RS07100	COG2205	protein histidine kinase activity
FCN51_RS07110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FCN51_RS07145	COG1278	Cold shock
FCN51_RS07150	COG1538	Outer membrane efflux protein
FCN51_RS07160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FCN51_RS07170	COG4302	ethanolamine ammonia-lyase activity
FCN51_RS07175	COG4303	Ethanolamine ammonia lyase large subunit
FCN51_RS07180	COG2207	Transcriptional regulator
FCN51_RS07185	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FCN51_RS07205	COG4208	sulfate ABC transporter
FCN51_RS07210	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FCN51_RS07215	COG1113	amino acid transport
FCN51_RS07230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FCN51_RS07235	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FCN51_RS07240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FCN51_RS07245	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FCN51_RS07250	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FCN51_RS07255	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FCN51_RS07260	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FCN51_RS07265	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FCN51_RS07295	COG0281	malic enzyme
FCN51_RS07305	COG0586	Pfam SNARE associated Golgi protein
FCN51_RS07310	COG1028	Short-chain dehydrogenase reductase Sdr
FCN51_RS07335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FCN51_RS07355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FCN51_RS07370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FCN51_RS07385	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FCN51_RS07405	COG0670	Belongs to the BI1 family
FCN51_RS07425	COG1573	uracil-dna glycosylase
FCN51_RS07435	COG1289	transmembrane transporter activity
FCN51_RS07440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FCN51_RS07450	COG2814	Major facilitator Superfamily
FCN51_RS07460	COG1612	heme a metabolic process
FCN51_RS07465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FCN51_RS07485	COG0768	penicillin binding
FCN51_RS07490	COG0772	Belongs to the SEDS family
FCN51_RS07525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FCN51_RS07530	COG1420	regulation of RNA biosynthetic process
FCN51_RS07535	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FCN51_RS07540	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FCN51_RS07555	COG0539	negative regulation of cytoplasmic translation
FCN51_RS07560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FCN51_RS07565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FCN51_RS07575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FCN51_RS07585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FCN51_RS07590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FCN51_RS07615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FCN51_RS07625	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FCN51_RS07645	COG0405	Gamma-glutamyltransferase
FCN51_RS07650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FCN51_RS07655	COG0156	8-amino-7-oxononanoate synthase activity
FCN51_RS07665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FCN51_RS07675	COG0126	phosphoglycerate kinase activity
FCN51_RS07690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FCN51_RS07700	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FCN51_RS07710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FCN51_RS07715	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FCN51_RS07720	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FCN51_RS07725	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FCN51_RS07735	COG1012	belongs to the aldehyde dehydrogenase family
FCN51_RS07740	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FCN51_RS07755	COG1570	exodeoxyribonuclease VII activity
FCN51_RS07765	COG0456	acetyltransferase
FCN51_RS07775	COG0778	Nitroreductase
FCN51_RS07800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FCN51_RS07810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FCN51_RS07815	COG2835	tetraacyldisaccharide 4'-kinase activity
FCN51_RS07825	COG2814	Major facilitator Superfamily
FCN51_RS07835	COG1671	Belongs to the UPF0178 family
FCN51_RS07845	COG0424	maF-like protein
FCN51_RS07850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FCN51_RS07855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FCN51_RS07875	COG1611	Belongs to the LOG family
FCN51_RS07895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FCN51_RS07900	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FCN51_RS07905	COG0445	tRNA wobble uridine modification
FCN51_RS07910	COG0357	Ribosomal RNA small subunit methyltransferase G
FCN51_RS07915	COG1192	Involved in chromosome partitioning
FCN51_RS07920	COG1475	DNA binding
FCN51_RS07950	COG0778	Nitroreductase
FCN51_RS07960	COG0140	phosphoribosyl-ATP diphosphatase activity
FCN51_RS07965	COG0107	imidazoleglycerol-phosphate synthase activity
FCN51_RS07970	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FCN51_RS07975	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FCN51_RS07980	COG0131	Imidazoleglycerol-phosphate dehydratase
FCN51_RS07995	COG1216	Glycosyl transferase, family 2
FCN51_RS08015	COG0776	regulation of translation
FCN51_RS08065	COG0668	transmembrane transport
FCN51_RS08075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FCN51_RS08080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FCN51_RS08085	COG0653	protein targeting
FCN51_RS08090	COG0217	transcriptional regulatory protein
FCN51_RS08095	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FCN51_RS08100	COG0632	four-way junction helicase activity
FCN51_RS08105	COG2255	four-way junction helicase activity
FCN51_RS08110	COG0824	Thioesterase
FCN51_RS08120	COG0848	biopolymer transport protein
FCN51_RS08130	COG0823	Involved in the tonB-independent uptake of proteins
FCN51_RS08135	COG2885	chlorophyll binding
FCN51_RS08145	COG0037	tRNA processing
FCN51_RS08150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FCN51_RS08160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FCN51_RS08165	COG0745	RESPONSE REGULATOR receiver
FCN51_RS08170	COG0802	atpase or kinase
FCN51_RS08175	COG2887	Belongs to the helicase family. UvrD subfamily
FCN51_RS08190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FCN51_RS08195	COG0285	dihydrofolate synthase activity
FCN51_RS08205	COG0215	cysteine-tRNA ligase activity
FCN51_RS08215	COG2945	thiolester hydrolase activity
FCN51_RS08225	COG1104	cysteine desulfurase activity
FCN51_RS08235	COG0482	sulfurtransferase activity
FCN51_RS08245	COG0438	transferase activity, transferring glycosyl groups
FCN51_RS08250	COG0564	pseudouridine synthase activity
FCN51_RS08255	COG1674	ftsk spoiiie
FCN51_RS08265	COG1091	dTDP-4-dehydrorhamnose reductase activity
FCN51_RS08270	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FCN51_RS08290	COG0406	alpha-ribazole phosphatase activity
FCN51_RS08295	COG0312	modulator of DNA gyrase
FCN51_RS08300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FCN51_RS08320	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FCN51_RS08330	COG0629	single-stranded DNA binding
FCN51_RS08335	COG0742	ribosomal rna small subunit methyltransferase
FCN51_RS08340	COG1187	pseudouridine synthase activity
FCN51_RS08345	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FCN51_RS08350	COG0590	tRNA wobble adenosine to inosine editing
FCN51_RS08355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FCN51_RS08360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FCN51_RS08370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FCN51_RS08450	COG0495	leucyl-tRNA aminoacylation
FCN51_RS08475	COG1194	a g-specific adenine glycosylase
FCN51_RS08480	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FCN51_RS08485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FCN51_RS08490	COG1132	(ABC) transporter
FCN51_RS08500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FCN51_RS08505	COG0154	amidase activity
FCN51_RS08510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FCN51_RS08515	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FCN51_RS08525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FCN51_RS08575	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FCN51_RS08580	COG2814	Major facilitator Superfamily
FCN51_RS08585	COG0439	Biotin carboxylase
FCN51_RS08590	COG0511	ligase activity, forming carbon-carbon bonds
FCN51_RS08595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FCN51_RS08605	COG1295	ribonuclease BN
FCN51_RS08625	COG4133	protoheme IX ABC transporter activity
FCN51_RS08635	COG1126	abc transporter atp-binding protein
FCN51_RS08640	COG0765	amino acid transport
FCN51_RS08655	COG0542	response to heat
FCN51_RS08665	COG0779	Required for maturation of 30S ribosomal subunits
FCN51_RS08680	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FCN51_RS08685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FCN51_RS08690	COG1522	sequence-specific DNA binding
FCN51_RS08695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FCN51_RS08700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FCN51_RS08715	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FCN51_RS08715	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FCN51_RS08730	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FCN51_RS08745	COG0489	protein tyrosine kinase activity
FCN51_RS08780	COG0129	dihydroxy-acid dehydratase activity
FCN51_RS08785	COG0573	inorganic phosphate transmembrane transporter activity
FCN51_RS08795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FCN51_RS08800	COG0704	Plays a role in the regulation of phosphate uptake
FCN51_RS08815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FCN51_RS08820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FCN51_RS08835	COG0513	Belongs to the DEAD box helicase family
FCN51_RS08845	COG0346	lactoylglutathione lyase activity
FCN51_RS08850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FCN51_RS08855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FCN51_RS08860	COG0552	protein localization to endoplasmic reticulum
FCN51_RS08870	COG0356	it plays a direct role in the translocation of protons across the membrane
FCN51_RS08875	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FCN51_RS08880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FCN51_RS08885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FCN51_RS08890	COG0463	Glycosyl transferase, family 2
FCN51_RS08895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FCN51_RS08905	COG2995	paraquat-inducible protein a
FCN51_RS08910	COG3008	intermembrane lipid transfer
FCN51_RS08920	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FCN51_RS08935	COG1410	methionine synthase
FCN51_RS08935	COG0646	methionine synthase
FCN51_RS08980	COG3008	intermembrane lipid transfer
FCN51_RS08980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FCN51_RS08985	COG1127	ABC transporter
FCN51_RS08990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FCN51_RS08995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FCN51_RS09000	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FCN51_RS09005	COG1185	polyribonucleotide nucleotidyltransferase activity
FCN51_RS09020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FCN51_RS09025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FCN51_RS09030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FCN51_RS09050	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FCN51_RS09055	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FCN51_RS09060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FCN51_RS09065	COG0509	glycine decarboxylation via glycine cleavage system
FCN51_RS09070	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FCN51_RS09070	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FCN51_RS09090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FCN51_RS09100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FCN51_RS09150	COG1846	Transcriptional regulator
FCN51_RS09155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FCN51_RS09160	COG2080	2 iron, 2 sulfur cluster binding
FCN51_RS09165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FCN51_RS09165	COG2010	Cytochrome c
FCN51_RS09170	COG2309	aminopeptidase activity
FCN51_RS09175	COG1335	isochorismatase
FCN51_RS09180	COG0596	Alpha beta hydrolase
FCN51_RS09185	COG3473	Maleate cis-trans isomerase
FCN51_RS09190	COG2271	Major facilitator Superfamily
FCN51_RS09200	COG0583	DNA-binding transcription factor activity
FCN51_RS09245	COG0450	alkyl hydroperoxide reductase
FCN51_RS09250	COG0640	Transcriptional regulator
FCN51_RS09255	COG2818	Glycosylase
FCN51_RS09265	COG1393	Belongs to the ArsC family
FCN51_RS09290	COG3961	Belongs to the TPP enzyme family
FCN51_RS09295	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FCN51_RS09300	COG0829	nickel cation binding
FCN51_RS09305	COG0831	urea catabolic process
FCN51_RS09310	COG0832	Belongs to the urease beta subunit family
FCN51_RS09315	COG0804	urea catabolic process
FCN51_RS09320	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FCN51_RS09325	COG0830	nickel cation binding
FCN51_RS09330	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FCN51_RS09345	COG0745	RESPONSE REGULATOR receiver
FCN51_RS09350	COG0784	Response regulator, receiver
FCN51_RS09350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FCN51_RS09350	COG2198	Histidine kinase
FCN51_RS09350	COG2205	protein histidine kinase activity
FCN51_RS09360	COG0559	Belongs to the binding-protein-dependent transport system permease family
FCN51_RS09370	COG0411	ABC transporter
FCN51_RS09375	COG0410	ABC transporter
FCN51_RS09395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FCN51_RS09400	COG3158	transport of potassium into the cell
FCN51_RS09410	COG1063	alcohol dehydrogenase
FCN51_RS09435	COG3265	gluconokinase activity
FCN51_RS09440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FCN51_RS09445	COG0363	glucosamine-6-phosphate deaminase activity
FCN51_RS09455	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FCN51_RS09460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FCN51_RS09475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FCN51_RS09490	COG1742	UPF0060 membrane protein
FCN51_RS09525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FCN51_RS09545	COG0741	lytic transglycosylase activity
FCN51_RS09545	COG1196	nuclear chromosome segregation
FCN51_RS09545	COG0739	heme binding
FCN51_RS09550	COG2814	Major facilitator Superfamily
FCN51_RS09565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FCN51_RS09565	COG0519	Catalyzes the synthesis of GMP from XMP
FCN51_RS09585	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FCN51_RS09600	COG0735	belongs to the Fur family
FCN51_RS09610	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FCN51_RS09615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FCN51_RS09620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FCN51_RS09625	COG1024	Enoyl-CoA hydratase
FCN51_RS09630	COG1584	GPR1 FUN34 yaaH family protein
FCN51_RS09635	COG1289	transmembrane transporter activity
FCN51_RS09660	COG1797	cobyrinic acid a,c-diamide synthase activity
FCN51_RS09675	COG1492	cobalamin metabolic process
FCN51_RS09680	COG0778	Nitroreductase
FCN51_RS09695	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FCN51_RS09700	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FCN51_RS09710	COG2814	Major facilitator Superfamily
FCN51_RS09745	COG1301	dicarboxylic acid transport
FCN51_RS09765	COG0848	biopolymer transport protein
FCN51_RS09775	COG4774	siderophore transport
FCN51_RS09790	COG3128	pkhd-type hydroxylase
FCN51_RS09805	COG1012	belongs to the aldehyde dehydrogenase family
FCN51_RS09810	COG3842	ATPase activity
FCN51_RS09815	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FCN51_RS09820	COG1176	ABC-type spermidine putrescine transport system, permease component I
FCN51_RS09825	COG1177	transmembrane transport
FCN51_RS09850	COG1012	belongs to the aldehyde dehydrogenase family
FCN51_RS09870	COG4638	Rieske (2fe-2S)
FCN51_RS09895	COG0235	Class ii aldolase
FCN51_RS09900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FCN51_RS09905	COG0154	amidase activity
FCN51_RS09910	COG1846	Transcriptional regulator
FCN51_RS09925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FCN51_RS09925	COG1648	precorrin-2 dehydrogenase activity
FCN51_RS09930	COG0277	FAD linked oxidase domain protein
FCN51_RS09940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FCN51_RS09945	COG2011	ABC-type metal ion transport system permease component
FCN51_RS09955	COG3620	sequence-specific DNA binding
FCN51_RS09965	COG3145	DNA-N1-methyladenine dioxygenase activity
FCN51_RS09990	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FCN51_RS10000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FCN51_RS10005	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FCN51_RS10015	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FCN51_RS10025	COG0284	orotidine-5'-phosphate decarboxylase activity
FCN51_RS10030	COG0135	phosphoribosylanthranilate isomerase activity
FCN51_RS10045	COG1953	Uracil, thiamine, allantoin
FCN51_RS10065	COG0493	'glutamate synthase
FCN51_RS10080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FCN51_RS10090	COG1942	4-Oxalocrotonate Tautomerase
FCN51_RS10110	COG1113	amino acid transport
FCN51_RS10125	COG1271	oxidase subunit
FCN51_RS10130	COG1294	oxidase, subunit
FCN51_RS10155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FCN51_RS10155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FCN51_RS10160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FCN51_RS10165	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FCN51_RS10170	COG1120	ATPase activity
FCN51_RS10175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FCN51_RS10180	COG0564	pseudouridine synthase activity
FCN51_RS10185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FCN51_RS10195	COG1494	fructose-1,6-bisphosphatase
FCN51_RS10205	COG0436	Aminotransferase
FCN51_RS10215	COG0740	serine-type endopeptidase activity
FCN51_RS10225	COG0535	radical SAM domain protein
FCN51_RS10235	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
FCN51_RS10240	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FCN51_RS10265	COG0708	Exodeoxyribonuclease III
FCN51_RS10270	COG0316	Belongs to the HesB IscA family
FCN51_RS10275	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FCN51_RS10280	COG0018	arginyl-trna synthetase
FCN51_RS10290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FCN51_RS10295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FCN51_RS10300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FCN51_RS10305	COG0805	protein transport
FCN51_RS10310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FCN51_RS10320	COG4232	protein-disulfide reductase activity
FCN51_RS10505	COG1783	phage Terminase large subunit
FCN51_RS10600	COG2856	Zn peptidase
FCN51_RS10740	COG1289	transmembrane transporter activity
FCN51_RS10745	COG0583	DNA-binding transcription factor activity
FCN51_RS10805	COG1999	signal sequence binding
FCN51_RS10815	COG0028	Belongs to the TPP enzyme family
FCN51_RS10820	COG1028	Short-chain dehydrogenase reductase Sdr
FCN51_RS10835	COG0297	glycogen (starch) synthase activity
FCN51_RS10840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FCN51_RS10845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FCN51_RS10855	COG0300	oxidoreductase activity
FCN51_RS10890	COG4221	oxidoreductase activity
FCN51_RS10900	COG1984	allophanate hydrolase subunit 2
FCN51_RS10905	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FCN51_RS10910	COG0697	spore germination
FCN51_RS10950	COG0583	DNA-binding transcription factor activity
FCN51_RS10960	COG0431	NADPH-dependent FMN reductase
FCN51_RS10970	COG2814	Major facilitator Superfamily
FCN51_RS10975	COG1012	belongs to the aldehyde dehydrogenase family
FCN51_RS10985	COG1252	NADH dehydrogenase
FCN51_RS10990	COG1309	transcriptional regulator
FCN51_RS11015	COG2308	Evidence 4 Homologs of previously reported genes of
FCN51_RS11030	COG0277	FAD linked oxidase domain protein
FCN51_RS11060	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FCN51_RS11070	COG0424	maF-like protein
FCN51_RS11075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FCN51_RS11080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FCN51_RS11085	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FCN51_RS11090	COG1530	ribonuclease E activity
FCN51_RS11095	COG0860	N-Acetylmuramoyl-L-alanine amidase
FCN51_RS11140	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FCN51_RS11145	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FCN51_RS11150	COG0328	RNA-DNA hybrid ribonuclease activity
FCN51_RS11165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FCN51_RS11185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FCN51_RS11190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FCN51_RS11200	COG3850	Histidine kinase
FCN51_RS11200	COG0642	Histidine kinase
FCN51_RS11205	COG0745	RESPONSE REGULATOR receiver
FCN51_RS11215	COG0488	(ABC) transporter
FCN51_RS11220	COG0105	UTP biosynthetic process
FCN51_RS11225	COG1032	radical SAM domain protein
FCN51_RS11230	COG3161	chorismate lyase activity
FCN51_RS11250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FCN51_RS11275	COG0251	oxidation-reduction process
FCN51_RS11280	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FCN51_RS11285	COG0587	DNA-directed DNA polymerase activity
FCN51_RS11290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FCN51_RS11315	COG0052	Belongs to the universal ribosomal protein uS2 family
FCN51_RS11320	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FCN51_RS11325	COG1381	Involved in DNA repair and RecF pathway recombination
FCN51_RS11330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FCN51_RS11335	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FCN51_RS11340	COG0113	porphobilinogen synthase activity
FCN51_RS11345	COG0531	amino acid
FCN51_RS11350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FCN51_RS11355	COG2988	succinylglutamate desuccinylase activity
FCN51_RS11370	COG0513	Belongs to the DEAD box helicase family
FCN51_RS11385	COG0560	Phosphoserine phosphatase
FCN51_RS11390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FCN51_RS11395	COG0028	Belongs to the TPP enzyme family
FCN51_RS11405	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FCN51_RS11415	COG2132	Multicopper oxidase
FCN51_RS11425	COG2217	Heavy metal translocating P-type atpase
FCN51_RS11435	COG1335	isochorismatase
FCN51_RS11440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FCN51_RS11455	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FCN51_RS11475	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FCN51_RS11480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FCN51_RS11480	COG0574	Belongs to the PEP-utilizing enzyme family
FCN51_RS11485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FCN51_RS11490	COG0497	DNA recombination
FCN51_RS11495	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FCN51_RS11500	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FCN51_RS11510	COG0849	cell division
FCN51_RS11515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FCN51_RS11520	COG1181	Belongs to the D-alanine--D-alanine ligase family
FCN51_RS11525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FCN51_RS11530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FCN51_RS11545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FCN51_RS11550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FCN51_RS11560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FCN51_RS11575	COG0275	rRNA processing
FCN51_RS11580	COG2001	Belongs to the MraZ family
FCN51_RS11600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FCN51_RS11605	COG3750	Belongs to the UPF0335 family
FCN51_RS11615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FCN51_RS11620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FCN51_RS11625	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FCN51_RS11630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FCN51_RS11710	COG1061	Type III restriction enzyme res subunit
FCN51_RS11715	COG1002	Type II restriction enzyme, methylase subunits
FCN51_RS11720	COG0582	viral genome integration into host DNA
FCN51_RS11770	COG0723	plastoquinol--plastocyanin reductase activity
FCN51_RS11775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FCN51_RS11775	COG2857	Cytochrome c1
FCN51_RS11780	COG2857	Cytochrome c1
FCN51_RS11780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FCN51_RS11790	COG0307	riboflavin synthase, alpha
FCN51_RS11795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FCN51_RS11795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FCN51_RS11800	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FCN51_RS11830	COG1566	PFAM secretion protein HlyD family protein
FCN51_RS11860	COG0521	Mo-molybdopterin cofactor biosynthetic process
FCN51_RS11870	COG0302	gtp cyclohydrolase
FCN51_RS11875	COG2967	ApaG domain
FCN51_RS11890	COG0494	nUDIX hydrolase
FCN51_RS11915	COG4974	Belongs to the 'phage' integrase family
FCN51_RS11935	COG0004	ammonium transporteR
FCN51_RS11975	COG0459	protein refolding
FCN51_RS11980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FCN51_RS11985	COG0412	Dienelactone hydrolase
FCN51_RS11990	COG1278	Cold shock
FCN51_RS11995	COG1199	ATP-dependent helicase activity
FCN51_RS12000	COG0483	inositol monophosphate 1-phosphatase activity
FCN51_RS12005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FCN51_RS12020	COG0586	Pfam SNARE associated Golgi protein
FCN51_RS12025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FCN51_RS12035	COG0347	Belongs to the P(II) protein family
FCN51_RS12040	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FCN51_RS12055	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FCN51_RS12065	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FCN51_RS12105	COG0463	Glycosyl transferase, family 2
FCN51_RS12110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FCN51_RS12110	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FCN51_RS12135	COG2204	response regulator
FCN51_RS12140	COG1923	regulation of RNA biosynthetic process
FCN51_RS12145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FCN51_RS12150	COG1051	belongs to the nudix hydrolase family
FCN51_RS12160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FCN51_RS12180	COG0659	secondary active sulfate transmembrane transporter activity
FCN51_RS12185	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FCN51_RS12190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FCN51_RS12200	COG0367	asparagine synthase
FCN51_RS12205	COG0438	transferase activity, transferring glycosyl groups
FCN51_RS12230	COG1160	GTP binding
FCN51_RS12240	COG3572	ergothioneine biosynthetic process
FCN51_RS12260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FCN51_RS12265	COG0564	pseudouridine synthase activity
FCN51_RS12290	COG0228	four-way junction DNA binding
FCN51_RS12295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FCN51_RS12300	COG0336	Belongs to the RNA methyltransferase TrmD family
FCN51_RS12305	COG0335	large ribosomal subunit rRNA binding
FCN51_RS12310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FCN51_RS12315	COG0066	3-isopropylmalate dehydratase activity
FCN51_RS12320	COG0473	3-isopropylmalate dehydrogenase activity
FCN51_RS12325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FCN51_RS12330	COG0242	peptide deformylase activity
FCN51_RS12340	COG1846	Transcriptional regulator
FCN51_RS12345	COG0745	RESPONSE REGULATOR receiver
FCN51_RS12350	COG2205	protein histidine kinase activity
FCN51_RS12365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FCN51_RS12370	COG0416	fatty acid biosynthetic process
FCN51_RS12375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FCN51_RS12380	COG0776	regulation of translation
FCN51_RS12410	COG0776	regulation of translation
FCN51_RS12415	COG4957	zinc ion binding
FCN51_RS12420	COG0583	DNA-binding transcription factor activity
FCN51_RS12425	COG0492	ferredoxin-NADP+ reductase activity
FCN51_RS12430	COG1522	sequence-specific DNA binding
FCN51_RS12450	COG2226	methyltransferase
FCN51_RS12460	COG0109	protoheme IX farnesyltransferase activity
FCN51_RS12475	COG0312	modulator of DNA gyrase
FCN51_RS12480	COG0612	Peptidase, M16
FCN51_RS12505	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FCN51_RS12510	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FCN51_RS12520	COG5265	(ABC) transporter
FCN51_RS12530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FCN51_RS12540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FCN51_RS12550	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FCN51_RS12555	COG2733	membrane
FCN51_RS12565	COG0719	Fe-S assembly protein
FCN51_RS12570	COG0396	ATPase activity
FCN51_RS12575	COG0719	Fe-S assembly protein
FCN51_RS12580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FCN51_RS12590	COG2151	metal-sulfur cluster biosynthetic enzyme
FCN51_RS12595	COG0316	Belongs to the HesB IscA family
FCN51_RS12600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FCN51_RS12605	COG0513	Belongs to the DEAD box helicase family
FCN51_RS12615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FCN51_RS12615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FCN51_RS12625	COG0544	peptidyl-prolyl cis-trans isomerase activity
FCN51_RS12630	COG0740	serine-type endopeptidase activity
FCN51_RS12635	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FCN51_RS12645	COG0776	regulation of translation
FCN51_RS12665	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FCN51_RS12670	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FCN51_RS12675	COG0649	NAD binding
FCN51_RS12680	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FCN51_RS12690	COG1034	ATP synthesis coupled electron transport
FCN51_RS12695	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FCN51_RS12700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FCN51_RS12710	COG0713	ATP synthesis coupled electron transport
FCN51_RS12720	COG1007	ATP synthesis coupled electron transport
FCN51_RS12730	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FCN51_RS12740	COG0442	prolyl-tRNA aminoacylation
FCN51_RS12750	COG1136	(ABC) transporter
FCN51_RS12755	COG0386	Belongs to the glutathione peroxidase family
FCN51_RS12770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FCN51_RS12775	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FCN51_RS12780	COG0546	phosphoglycolate phosphatase activity
FCN51_RS12805	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FCN51_RS12820	COG0156	8-amino-7-oxononanoate synthase activity
FCN51_RS12830	COG0318	PFAM AMP-dependent synthetase and ligase
FCN51_RS12910	COG3551	Protein conserved in bacteria
FCN51_RS12915	COG2207	Transcriptional regulator
FCN51_RS12940	COG1570	exodeoxyribonuclease VII activity
FCN51_RS12950	COG2963	transposase activity
FCN51_RS12960	COG4372	Transposase
FCN51_RS13035	COG0745	RESPONSE REGULATOR receiver
FCN51_RS13040	COG0642	Histidine kinase
FCN51_RS13065	COG4774	siderophore transport
FCN51_RS13110	COG2814	Major facilitator Superfamily
FCN51_RS13125	COG1028	Short-chain dehydrogenase reductase Sdr
FCN51_RS13135	COG1028	Short-chain dehydrogenase reductase Sdr
FCN51_RS13150	COG0028	Belongs to the TPP enzyme family
FCN51_RS13170	COG1285	pathogenesis
FCN51_RS13180	COG3685	Protein conserved in bacteria
FCN51_RS13190	COG1064	alcohol dehydrogenase
FCN51_RS13205	COG0583	DNA-binding transcription factor activity
FCN51_RS13210	COG0488	(ABC) transporter
FCN51_RS13230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FCN51_RS13240	COG2985	domain, Protein
FCN51_RS13250	COG0252	asparaginase activity
FCN51_RS13265	COG4774	siderophore transport
FCN51_RS13270	COG3128	pkhd-type hydroxylase
FCN51_RS13275	COG4988	ABC transporter
FCN51_RS13280	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FCN51_RS13285	COG1271	oxidase subunit
FCN51_RS13290	COG1294	oxidase, subunit
FCN51_RS13310	COG0668	transmembrane transport
FCN51_RS13325	COG1032	radical SAM domain protein
FCN51_RS13335	COG1289	transmembrane transporter activity
FCN51_RS13340	COG1566	PFAM secretion protein HlyD family protein
FCN51_RS13355	COG1695	Transcriptional regulator
FCN51_RS13370	COG0477	Major facilitator Superfamily
FCN51_RS13395	COG3511	phospholipase C
FCN51_RS13410	COG0671	phosphoesterase, PA-phosphatase related
FCN51_RS13415	COG2070	2-Nitropropane dioxygenase
FCN51_RS13420	COG4608	Belongs to the ABC transporter superfamily
FCN51_RS13475	COG2337	Toxic component of a toxin-antitoxin (TA) module
FCN51_RS13480	COG2336	PFAM SpoVT AbrB
FCN51_RS13510	COG1271	oxidase subunit
FCN51_RS13515	COG1294	oxidase, subunit
FCN51_RS13585	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FCN51_RS13595	COG1012	belongs to the aldehyde dehydrogenase family
FCN51_RS13600	COG2072	flavoprotein involved in K transport
FCN51_RS13620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FCN51_RS13620	COG2146	nitrite reductase [NAD(P)H] activity
FCN51_RS13630	COG2223	nitrite transmembrane transporter activity
FCN51_RS13640	COG0642	Histidine kinase
FCN51_RS13645	COG0745	RESPONSE REGULATOR receiver
FCN51_RS13730	COG1902	pentaerythritol trinitrate reductase activity
FCN51_RS13735	COG3077	Addiction module antitoxin, RelB DinJ family
FCN51_RS13740	COG2026	Addiction module toxin, RelE StbE family
FCN51_RS13755	COG2963	transposase activity
FCN51_RS13765	COG4372	Transposase
FCN51_RS13795	COG3189	MarR family transcriptional regulator
FCN51_RS13845	COG1309	transcriptional regulator
FCN51_RS13850	COG1979	alcohol dehydrogenase
FCN51_RS13855	COG1012	belongs to the aldehyde dehydrogenase family
FCN51_RS13875	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
FCN51_RS13885	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FCN51_RS13900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FCN51_RS13910	COG2072	flavoprotein involved in K transport
FCN51_RS13915	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FCN51_RS13930	COG0583	DNA-binding transcription factor activity
FCN51_RS13970	COG4974	Belongs to the 'phage' integrase family
FCN51_RS14005	COG4716	Myosin-crossreactive antigen
FCN51_RS14015	COG2026	Addiction module toxin, RelE StbE family
FCN51_RS14020	COG3077	Addiction module antitoxin, RelB DinJ family
FCN51_RS14060	COG2072	flavoprotein involved in K transport
FCN51_RS14075	COG2144	transferase activity, transferring acyl groups
FCN51_RS14100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FCN51_RS14110	COG0583	DNA-binding transcription factor activity
FCN51_RS14195	COG1959	2 iron, 2 sulfur cluster binding
FCN51_RS14200	COG1017	nitric oxide dioxygenase activity
FCN51_RS14200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FCN51_RS14205	COG3256	nitric oxide reductase
FCN51_RS14210	COG3189	MarR family transcriptional regulator